A0A2K5XFW2_MANLE Loading...

Solute carrier family 11 member 2

AlphaFold DB , UniProt , Accession A0A2K5XFW2, Species MANLE (Mandrillus leucophaeus, Drill), Gene SLC11A2, Length 568 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	34.3	Very low	26.9	Very low	233 Å²	233	155.2 Å²	155.2	100%	1.148	83%	0.828	S	S	*	*				0	113.4	0	-69.2	148.3	174.9	0	0	105.6
2	V	27.7	Very low	26.9	Very low	124 Å²	124	156.1 Å²	156.1	75%	0.752	83%	0.833	S	S	*	*				64.3	98.3	58.4	-173.3	0	0	0	0	107
3	L	27.1	Very low	26.7	Very low	170 Å²	170	152.6 Å²	152.6	89%	0.89	83%	0.828	S	S	*	*				57.9	132.6	84.4	-64.2	166.8	0	0	0	111.6
4	G	26	Very low	26.7	Very low	69 Å²	69	152.2 Å²	152.2	71%	0.711	83%	0.833	S	S	*	*			cis	178.2	-165.4	-1.6	0	0	0	0	0	110.7
5	L	30.1	Very low	26.5	Very low	169 Å²	169	149.9 Å²	149.9	89%	0.885	83%	0.832	S	S	*	*			trans	0.7	132.2	160.9	-78.4	156.8	0	0	0	119
6	E	26.7	Very low	26.4	Very low	195 Å²	195	144.8 Å²	144.8	91%	0.911	82%	0.823	S	S	*	*				-144.8	160.3	127.3	-132.6	-176.2	141.4	0	0	111.8
7	Q	26.1	Very low	26.3	Very low	165 Å²	165	144.6 Å²	144.6	77%	0.771	82%	0.82	S	S	*	*			trans	-134.7	138.6	-167.6	174.2	-175.4	-1.4	0	0	107.6
8	K	24.6	Very low	26.3	Very low	207 Å²	207	146.7 Å²	146.7	90%	0.9	82%	0.821	S	S	*	*			trans	-142.8	131.9	168.7	-145.7	162.9	-169.2	169.2	0	114
9	M	24.2	Very low	26.2	Very low	138 Å²	138	143.5 Å²	143.5	68%	0.68	82%	0.824	S	S	*	*			trans	-116.8	156.3	178.2	167.6	176.2	156.6	0	0	107.6	D11	M9-D11 WeakPolarHBondContact CE-OD1 3.41Å
10	S	24.2	Very low	26.1	Very low	115 Å²	115	146.5 Å²	146.5	80%	0.804	83%	0.83	S	S	*	*			trans	-148.3	123.1	171.8	53.5	0	0	0	0	109.1
11	D	25.2	Very low	26	Very low	122 Å²	122	145.8 Å²	145.8	65%	0.652	84%	0.835	S	S	*	*			trans	-81.9	161.7	-177.7	-60.4	-76.3	0	0	0	113.6	M9	M9-D11 WeakPolarHBondContact CE-OD1 3.41Å
12	D	26.6	Very low	25.5	Very low	166 Å²	166	138.7 Å²	138.7	89%	0.888	81%	0.813	S	S	*	*			trans	167.5	146	140.9	-92.4	-25.8	0	0	0	108.9
13	S	24.9	Very low	25.3	Very low	111 Å²	111	138.3 Å²	138.3	78%	0.776	82%	0.815	S	S	*	*			cis	-155.6	-170.6	0.7	52.3	0	0	0	0	110.5
14	V	25.6	Very low	25.1	Very low	147 Å²	147	138.5 Å²	138.5	89%	0.891	82%	0.816	S	S	*	*			trans	-125.3	136	-158	175.5	0	0	0	0	116.6
15	S	24.8	Very low	25	Very low	118 Å²	118	138.9 Å²	138.9	83%	0.825	82%	0.82	S	S	*	*			trans	-170.1	166	154.7	57.4	0	0	0	0	110
16	G	23.9	Very low	24.7	Very low	67 Å²	67	137.5 Å²	137.5	69%	0.691	82%	0.818	S	S	*	*			cis	118.8	124.2	-8.6	0	0	0	0	0	114.3
17	D	25.6	Very low	24.6	Very low	143 Å²	143	133.9 Å²	133.9	77%	0.765	81%	0.81	S	S	*	*			cis	-165.8	173.2	-10.4	-147.6	-57	0	0	0	111.4
18	H	25.3	Very low	24.5	Very low	182 Å²	182	132.9 Å²	132.9	84%	0.843	81%	0.81	S	S	*	*			trans	68.1	141.7	163.2	-71.8	1.6	0	0	0	122.3
19	G	24.5	Very low	24.6	Very low	85 Å²	85	128.6 Å²	128.6	88%	0.876	80%	0.803	S	S	*	*			trans	147.9	115.8	154.4	0	0	0	0	0	117.8
20	E	25	Very low	24.6	Very low	203 Å²	203	129.4 Å²	129.4	95%	0.949	82%	0.815	S	S	*	*			trans	-104.8	142.8	168.5	-69.6	-177.1	99.4	0	0	112.5
21	S	24	Very low	24.7	Very low	133 Å²	133	129.1 Å²	129.1	93%	0.93	81%	0.813	S	S	*	*			trans	-169.1	-179.5	144	-149.2	0	0	0	0	112.2
22	A	24.1	Very low	24.7	Very low	83 Å²	83	128.2 Å²	128.2	69%	0.686	82%	0.816	S	S	*	*			trans	-125.1	159.5	-155.3	0	0	0	0	0	118
23	C	22.2	Very low	24.9	Very low	116 Å²	116	127.3 Å²	127.3	78%	0.784	81%	0.811	S	S	*	*			trans	83.4	131	147.9	-73.9	0	0	0	0	123.5
24	L	23.4	Very low	25.3	Very low	174 Å²	174	127.1 Å²	127.1	91%	0.911	81%	0.807	S	S	*	*			trans	67.8	112.3	154.2	-94.5	71.2	0	0	0	120.6
25	G	23.2	Very low	25.4	Very low	77 Å²	77	125.8 Å²	125.8	79%	0.794	81%	0.805	S	S	*	*			trans	165.8	93	164.1	0	0	0	0	0	115.1
26	T	24	Very low	25.6	Very low	140 Å²	140	127.2 Å²	127.2	86%	0.859	80%	0.802	S	S	*	*			trans	-37.3	149.7	166.4	47.8	0	0	0	0	115.3
27	V	25.1	Very low	25.8	Very low	120 Å²	120	129.7 Å²	129.7	73%	0.727	81%	0.806	S	S	*	*			cis	-166.1	173.8	23.5	97.3	0	0	0	0	113.3
28	N	25.2	Very low	25.9	Very low	144 Å²	144	134.7 Å²	134.7	77%	0.77	81%	0.814	S	S	*	*			trans	73.9	123.4	169.3	-74.7	-14	0	0	0	119.8
29	P	26.8	Very low	26	Very low	116 Å²	116	131 Å²	131	75%	0.753	81%	0.809	S	S	*	*			trans	-93.7	139	169.1	35.8	-30.8	0	0	0	112.8
30	V	24.1	Very low	26.5	Very low	155 Å²	155	131.7 Å²	131.7	94%	0.939	80%	0.798	S	S	*	*			trans	-102.1	111.2	157.9	176.5	0	0	0	0	107.4
31	S	25.8	Very low	26.7	Very low	109 Å²	109	124.7 Å²	124.7	76%	0.762	78%	0.78	S	S	*	*			trans	-116.9	136.3	174.9	58.2	0	0	0	0	110.3
32	S	25.4	Very low	27.1	Very low	103 Å²	103	124.6 Å²	124.6	72%	0.72	77%	0.769	S	S	*	*			trans	-91.4	179.2	-166.8	49.5	0	0	0	0	114.7
33	N	30.7	Very low	27.3	Very low	147 Å²	147	124.8 Å²	124.8	79%	0.786	77%	0.765	S	S	*	*			trans	77.2	153.2	175.2	-61.2	-18.2	0	0	0	115
34	P	32.3	Very low	27.9	Very low	107 Å²	107	126.8 Å²	126.8	70%	0.695	76%	0.763	S	S	*	*			cis	-121.6	161.5	17.4	41.2	-29.1	0	0	0	116.9
35	S	28.1	Very low	28.5	Very low	119 Å²	119	126.2 Å²	126.2	83%	0.832	76%	0.756	S	S	*	*			trans	-84.7	113.9	161.1	40	0	0	0	0	110.7
36	L	28	Very low	29.1	Very low	149 Å²	149	131.5 Å²	131.5	78%	0.78	75%	0.753	S	S	*	*	P	Polyproline II helix	trans	-96.1	154.8	170	-85.6	153.6	0	0	0	110.8
37	P	29.6	Very low	30	Very low	118 Å²	118	130.7 Å²	130.7	77%	0.766	74%	0.738	S	S	*	*	P	Polyproline II helix	trans	-66.2	147.3	-177.3	-19.5	32.3	0	0	0	113.2	S39	P37-S39 PolarHBondContact O-N 2.8Å
38	R	27.3	Very low	30.8	Very low	249 Å²	249	126.5 Å²	126.5	94%	0.94	72%	0.716	S	S	*	*	P	Polyproline II helix	trans	-67	128.7	168.8	-78.9	179.6	169.3	162.7	-4.3	110.5
39	S	27.6	Very low	32	Very low	105 Å²	105	122.4 Å²	122.4	73%	0.734	70%	0.696	S	S	*	*	P	Polyproline II helix	trans	-65	144.6	158	-172.9	0	0	0	0	109.4	P37 G41	P37-S39 PolarHBondContact O-N 2.8Å; S39-G41 PolarHBondContact O-N 3.47Å
40	P	35	Very low	33.2	Very low	98 Å²	98	118.4 Å²	118.4	64%	0.636	67%	0.666	S	S	*	*	P	Polyproline II helix	trans	-65.3	132.9	176.8	26.8	-34.3	0	0	0	111
41	G	29.8	Very low	34.7	Very low	56 Å²	56	112 Å²	112	58%	0.577	63%	0.626	S	S	*	*			trans	-90.8	1.8	-176.6	0	0	0	0	0	114.7	S39 S43	S39-G41 PolarHBondContact O-N 3.47Å; G41-S43 PolarHBondContact O-N 3.06Å; G41-S43 VanDerWaalsContact O-N 3.1Å
42	D	32.5	Very low	36.1	Very low	132 Å²	132	112.1 Å²	112.1	71%	0.706	62%	0.618	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.1	0	-164.3	-47	-39.7	0	0	0	113.9
43	S	27.8	Very low	37.7	Very low	86 Å²	86	115.7 Å²	115.7	60%	0.601	62%	0.623	S	S	*	*	T	Hydrogen-bonded Turn	trans	-94.6	-7.3	-177.8	56.9	0	0	0	0	114.9	G41 F47	G41-S43 PolarHBondContact O-N 3.06Å; G41-S43 VanDerWaalsContact O-N 3.1Å; S43-F47 WeakPolarHBondContact O-CD2 3.41Å
44	E	34.7	Very low	39.7	Very low	158 Å²	158	113.3 Å²	113.3	74%	0.738	61%	0.606	S	S	*	*	S	Bend	trans	-92.1	-32.4	179.9	-64.5	-154.5	135.3	0	0	114.3	Y46 F47 A48	E44-Y46 VanDerWaalsContact C-N 3.32Å; E44-Y46 PolarHBondContact O-N 2.92Å; E44-F47 PolarHBondContact O-N 3.45Å; E44-F47 VanDerWaalsContact O-N 3.09Å; E44-A48 PolarHBondContact O-N 2.86Å
45	E	35.7	Very low	41.7	Very low	163 Å²	163	109.7 Å²	109.7	76%	0.762	58%	0.581	S	S	*	*	G	3₁₀ helix	trans	-56.9	-42	-176.3	-79.3	-160.5	129.5	0	0	113.2	F47 A48	E45-F47 PolarHBondContact O-N 3.16Å; E45-F47 VanDerWaalsContact O-N 3.11Å; E45-A48 PolarHBondContact O-N 2.98Å
46	Y	36.4	Very low	43.8	Very low	188 Å²	188	108 Å²	108	74%	0.737	57%	0.569	S	S	*	*	G	3₁₀ helix	trans	-65	-15.8	-178.2	-79.3	-86.1	0	0	0	114.2	E44	E44-Y46 VanDerWaalsContact C-N 3.32Å; E44-Y46 PolarHBondContact O-N 2.92Å
47	F	41.3	Very low	46.1	Very low	122 Å²	122	103 Å²	103	54%	0.535	54%	0.543	S	S	.	.	G	3₁₀ helix	trans	-114.6	5.2	-175.4	-61.2	-87.2	0	0	0	113.8	S43 E44 E45 T49	S43-F47 WeakPolarHBondContact O-CD2 3.41Å; E44-F47 PolarHBondContact O-N 3.45Å; E44-F47 VanDerWaalsContact O-N 3.09Å; E45-F47 PolarHBondContact O-N 3.16Å; E45-F47 VanDerWaalsContact O-N 3.11Å; F47-T49 PolarHBondContact O-N 3.48Å
48	A	41.8	Very low	48	Very low	32 Å²	32	98.7 Å²	98.7	26%	0.264	52%	0.515	S	S	.	.			trans	-61.9	103.7	-177.4	0	0	0	0	0	113.1	E44 E45 N52 R408	E44-A48 PolarHBondContact O-N 2.86Å; E45-A48 PolarHBondContact O-N 2.98Å; A48-N52 WeakPolarHBondContact CB-ND2 3.42Å; A48-R408 PolarHBondContact O-NH2 2.96Å
49	T	51.5	Low	49.7	Very low	58 Å²	58	96 Å²	96	36%	0.356	51%	0.512	S	S	.	.			trans	-61.9	154.3	179.5	37.1	0	0	0	0	112.4	F47 F51 N52	F47-T49 PolarHBondContact O-N 3.48Å; T49-F51 PolarHBondContact O-N 3.48Å; T49-N52 PolarHBondContact O-N 3.39Å; T49-N52 PolarHBondContact O-OD1 3.38Å; T49-N52 PolarHBondContact OG1-OD1 3.36Å
50	Y	52.8	Low	51.4	Low	32 Å²	32	93.9 Å²	93.9	13%	0.125	49%	0.491	C	S	.	.	T	Hydrogen-bonded Turn	trans	-52.3	-7.4	176.7	-65.8	-91.2	0	0	0	115.8	F196 D200 Y392	Y50-F196 WeakPolarHBondContact OH-CZ 3.25Å; Y50-D200 HydrophobicContact CE1-CB 3.79Å; Y50-D200 WeakPolarHBondContact CE1-OD1 3.5Å; Y50-D200 PolarHBondContact OH-OD2 3.13Å; Y50-D200 VanDerWaalsContact OH-OD2 3.07Å; Y50-Y392 AromaticContact CD1-CE1 3.89Å; Y50-Y392 HydrophobicContact CD1-CE1 3.89Å; Y50-Y392 HydrophobicContact CD2-CD1 4.49Å; Y50-Y392 AromaticContact CD2-CE1 3.82Å; Y50-Y392 HydrophobicContact CD2-CE1 3.82Å; Y50-Y392 AromaticContact CE1-CE1 3.58Å; Y50-Y392 HydrophobicContact CE1-CE1 3.58Å; Y50-Y392 AromaticContact CE1-CZ 3.77Å; Y50-Y392 WeakPolarHBondContact CE1-OH 3.19Å; Y50-Y392 HydrophobicContact CE2-CD1 4.22Å; Y50-Y392 AromaticContact CE2-CE1 3.53Å; Y50-Y392 HydrophobicContact CE2-CE1 3.53Å; Y50-Y392 AromaticContact CG-CE1 3.99Å; Y50-Y392 HydrophobicContact CG-CE1 3.99Å; Y50-Y392 AromaticContact CZ-CE1 3.39Å; Y50-Y392 AromaticContact CZ-CZ 3.89Å
51	F	55.4	Low	52.2	Low	21 Å²	21	97.6 Å²	97.6	9%	0.092	50%	0.5	C	S	.	.	T	Hydrogen-bonded Turn	trans	-114.8	20	-179.4	-51.1	-38.7	0	0	0	113.4	T49 K54 L204 A274 K277 F396	T49-F51 PolarHBondContact O-N 3.48Å; F51-K54 HydrophobicContact CB-CG 4.41Å; F51-K54 WeakPolarHBondContact O-CG 3.39Å; F51-L204 HydrophobicContact CD1-CD1 4.16Å; F51-L204 HydrophobicContact CE1-CD1 4.03Å; F51-A274 WeakPolarHBondContact CE2-O 3.45Å; F51-A274 WeakPolarHBondContact CZ-O 3.17Å; F51-K277 HydrophobicContact CD2-CB 4.23Å; F51-K277 HydrophobicContact CE2-CB 4.16Å; F51-F396 AromaticContact CE2-CE1 3.67Å; F51-F396 HydrophobicContact CE2-CE1 3.67Å; F51-F396 AromaticContact CE2-CZ 3.7Å; F51-F396 HydrophobicContact CE2-CZ 3.7Å; F51-F396 HydrophobicContact CZ-CE1 4.11Å; F51-F396 AromaticContact CZ-CZ 3.64Å; F51-F396 HydrophobicContact CZ-CZ 3.64Å
52	N	55.4	Low	53.4	Low	112 Å²	112	105.2 Å²	105.2	60%	0.599	51%	0.513	S	S	*	.	S	Bend	trans	-67.5	-47.3	171.9	-79.2	19	0	0	0	110.8	A48 T49 K54	A48-N52 WeakPolarHBondContact CB-ND2 3.42Å; T49-N52 PolarHBondContact O-N 3.39Å; T49-N52 PolarHBondContact O-OD1 3.38Å; T49-N52 PolarHBondContact OG1-OD1 3.36Å; N52-K54 PolarHBondContact O-N 3.27Å
53	E	57.5	Low	54.4	Low	177 Å²	177	102.1 Å²	102.1	83%	0.827	50%	0.501	S	S	*	.	S	Bend	trans	-89	82.7	164	-71.9	-165.1	128.4	0	0	110.6
54	K	72.4	Confident	56.1	Low	98 Å²	98	103.3 Å²	103.3	43%	0.426	51%	0.508	S	S	.	.	P	Polyproline II helix	trans	-70	134.2	169.4	-60	179.2	-170.4	141.2	0	110	F51 N52 S56 S278 Q280	F51-K54 HydrophobicContact CB-CG 4.41Å; F51-K54 WeakPolarHBondContact O-CG 3.39Å; N52-K54 PolarHBondContact O-N 3.27Å; K54-S56 PolarHBondContact O-N 3.5Å; K54-S278 WeakPolarHBondContact CA-O 3.48Å; K54-Q280 HydrophobicContact CB-CG 3.36Å; K54-Q280 HydrophobicContact CD-CG 4.19Å; K54-Q280 HydrophobicContact CG-CG 4.41Å; K54-Q280 PolarHBondContact O-NE2 2.86Å
55	I	75.6	Confident	58.1	Low	31 Å²	31	99 Å²	99	16%	0.159	49%	0.488	C	S	.	.	B	Isolated β-bridge	trans	-66.4	122.3	177.4	-68.1	153.5	0	0	0	109.4	L204 R205 S278 R279 Q280	I55-L204 HydrophobicContact CD1-CD2 3.56Å; I55-R205 HydrophobicContact CD1-CG 3.98Å; I55-R205 HydrophobicContact CG1-CG 4.45Å; I55-S278 PolarHBondContact N-O 3.46Å; I55-S278 VanDerWaalsContact N-O 3.09Å; I55-R279 VanDerWaalsContact CD1-CZ 3.48Å; I55-Q280 PolarHBondContact O-N 2.69Å
56	S	71.1	Confident	60.4	Low	84 Å²	84	92 Å²	92	59%	0.587	46%	0.456	S	S	*	.	P	Polyproline II helix	trans	-70.8	138.7	170.6	47.1	0	0	0	0	110.6	K54	K54-S56 PolarHBondContact O-N 3.5Å
57	I	76.7	Confident	62.6	Low	44 Å²	44	90.7 Å²	90.7	23%	0.226	46%	0.455	C	S	.	.	P	Polyproline II helix	trans	-84.1	136.7	175.1	-58.1	171.9	0	0	0	107.9	E59 K69 F73 Q280 V281	I57-E59 PolarHBondContact O-N 2.93Å; I57-K69 HydrophobicContact CG2-CG 4.34Å; I57-F73 HydrophobicContact CD1-CE1 3.9Å; I57-F73 HydrophobicContact CD1-CE2 3.88Å; I57-F73 HydrophobicContact CD1-CZ 3.3Å; I57-F73 HydrophobicContact CG1-CE2 4.4Å; I57-F73 HydrophobicContact CG1-CZ 4.17Å; I57-F73 HydrophobicContact CG2-CE2 4.35Å; I57-Q280 WeakPolarHBondContact CD1-O 3.3Å; I57-Q280 WeakPolarHBondContact CG1-O 3.35Å; I57-V281 HydrophobicContact CD1-CG2 4.19Å
58	P	69.4	Low	64.6	Low	27 Å²	27	92.3 Å²	92.3	18%	0.175	46%	0.457	C	S	.	.	P	Polyproline II helix	trans	-66.3	117.3	169	27.3	-32.4	0	0	0	109.9	E60 R68 K69 A72	P58-E60 PolarHBondContact O-N 3.42Å; P58-R68 HydrophobicContact CG-CG 4.28Å; P58-K69 HydrophobicContact CG-CG 4.26Å; P58-K69 WeakPolarHBondContact O-CE 3.4Å; P58-A72 VanDerWaalsContact CD-CB 3.5Å; P58-A72 HydrophobicContact CG-CB 4.22Å
59	E	63.3	Low	66.5	Low	192 Å²	192	91.6 Å²	91.6	90%	0.897	45%	0.448	S	S	*	.	P	Polyproline II helix	trans	-66.2	126.3	167.1	-68.2	-179.8	-168.2	0	0	109.1	I57	I57-E59 PolarHBondContact O-N 2.93Å
60	E	63.6	Low	68.2	Low	60 Å²	60	89.8 Å²	89.8	28%	0.28	44%	0.436	S	S	.	.			trans	-139	117.1	176.6	-64.9	-176.4	154.4	0	0	106.9	P58 Y62 S66 R68	P58-E60 PolarHBondContact O-N 3.42Å; E60-Y62 PolarHBondContact O-N 3.42Å; E60-S66 WeakPolarHBondContact OE2-CB 3.43Å; E60-S66 PolarHBondContact OE2-OG 2.99Å; E60-R68 WeakPolarHBondContact OE1-CD 3.41Å; E60-R68 IonicContact OE1-CZ 2.7Å; E60-R68 IonicContact OE1-NE 3.25Å; E60-R68 IonicContact OE1-NH1 3.56Å; E60-R68 PolarHBondContact OE1-NH1 3.21Å
61	E	51.4	Low	69.7	Low	177 Å²	177	97 Å²	97	83%	0.827	46%	0.463	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.3	124.3	178.3	-75.8	-167.5	117.2	0	0	110.7
62	Y	54.5	Low	71	Confident	215 Å²	215	96.4 Å²	96.4	84%	0.843	46%	0.462	S	S	*	.	T	Hydrogen-bonded Turn	trans	51	62.2	166.1	-54.7	-73	0	0	0	117.6	E60	E60-Y62 PolarHBondContact O-N 3.42Å
63	S	55.2	Low	72.4	Confident	67 Å²	67	91.1 Å²	91.1	47%	0.469	43%	0.434	S	S	.	.			trans	-115.5	139.9	150.4	-177.3	0	0	0	0	112	F65	S63-F65 PolarHBondContact O-N 3Å; S63-F65 PolarHBondContact OG-N 3.42Å; S63-F65 PolarHBondContact OG-O 3.45Å
64	C	62.4	Low	73.8	Confident	111 Å²	111	84 Å²	84	75%	0.75	40%	0.403	S	S	*	.	S	Bend	trans	-67	-24.4	172	-173.6	0	0	0	0	112.2	K294	C64-K294 PolarHBondContact O-NZ 3.01Å
65	F	76.5	Confident	74.6	Confident	69 Å²	69	79.4 Å²	79.4	30%	0.303	38%	0.384	S	S	.	.			trans	-159.3	129.2	178.1	179.6	-103.5	0	0	0	110.5	S63 F67 L70 Y295 I298	S63-F65 PolarHBondContact O-N 3Å; S63-F65 PolarHBondContact OG-N 3.42Å; S63-F65 PolarHBondContact OG-O 3.45Å; F65-F67 HydrophobicContact CD1-CE2 4.38Å; F65-F67 HydrophobicContact CE1-CD1 4.02Å; F65-F67 HydrophobicContact CE1-CD2 4.04Å; F65-F67 AromaticContact CE1-CE1 3.84Å; F65-F67 HydrophobicContact CE1-CE1 3.84Å; F65-F67 AromaticContact CE1-CE2 3.86Å; F65-F67 HydrophobicContact CE1-CE2 3.86Å; F65-F67 HydrophobicContact CE1-CG 4.12Å; F65-F67 AromaticContact CE1-CZ 3.76Å; F65-F67 HydrophobicContact CE1-CZ 3.76Å; F65-F67 HydrophobicContact CZ-CD1 4.4Å; F65-F67 HydrophobicContact CZ-CE1 4.31Å; F65-L70 HydrophobicContact CE2-CD2 4.49Å; F65-L70 HydrophobicContact CZ-CD2 4Å; F65-Y295 AromaticContact CD2-CE1 3.81Å; F65-Y295 HydrophobicContact CD2-CE1 3.81Å; F65-Y295 HydrophobicContact CE2-CD1 4.4Å; F65-Y295 AromaticContact CE2-CE1 3.89Å; F65-Y295 HydrophobicContact CE2-CE1 3.89Å; F65-I298 HydrophobicContact CD2-CD1 4.33Å; F65-I298 HydrophobicContact CE2-CD1 3.97Å
66	S	83.4	Confident	75.2	Confident	15 Å²	15	78 Å²	78	11%	0.105	38%	0.376	C	S	.	.			trans	-124	126.4	175.8	168.8	0	0	0	0	110.1	E60 R68 K69 L70 Y295	E60-S66 WeakPolarHBondContact OE2-CB 3.43Å; E60-S66 PolarHBondContact OE2-OG 2.99Å; S66-R68 PolarHBondContact O-N 3.17Å; S66-R68 PolarHBondContact OG-N 3.2Å; S66-K69 PolarHBondContact O-N 2.85Å; S66-K69 PolarHBondContact OG-N 3.44Å; S66-L70 PolarHBondContact O-N 3.23Å; S66-Y295 PolarHBondContact N-OH 3.17Å
67	F	83.9	Confident	76.2	Confident	160 Å²	160	74 Å²	74	70%	0.702	35%	0.348	S	S	*	.	H	α-helix	trans	-64.6	-28.5	172.7	-75	-81.3	0	0	0	112.1	F65 L70 W71	F65-F67 HydrophobicContact CD1-CE2 4.38Å; F65-F67 HydrophobicContact CE1-CD1 4.02Å; F65-F67 HydrophobicContact CE1-CD2 4.04Å; F65-F67 AromaticContact CE1-CE1 3.84Å; F65-F67 HydrophobicContact CE1-CE1 3.84Å; F65-F67 AromaticContact CE1-CE2 3.86Å; F65-F67 HydrophobicContact CE1-CE2 3.86Å; F65-F67 HydrophobicContact CE1-CG 4.12Å; F65-F67 AromaticContact CE1-CZ 3.76Å; F65-F67 HydrophobicContact CE1-CZ 3.76Å; F65-F67 HydrophobicContact CZ-CD1 4.4Å; F65-F67 HydrophobicContact CZ-CE1 4.31Å; F67-L70 PolarHBondContact O-N 3.04Å; F67-W71 WeakPolarHBondContact O-CB 3.49Å; F67-W71 PolarHBondContact O-N 3.08Å
68	R	82.9	Confident	76.8	Confident	156 Å²	156	74.2 Å²	74.2	59%	0.589	35%	0.348	S	S	*	.	H	α-helix	trans	-71.5	-42	175.9	-167	-159.7	-174.8	-171.1	-1.2	111.2	P58 E60 S66 W71 A72	P58-R68 HydrophobicContact CG-CG 4.28Å; E60-R68 WeakPolarHBondContact OE1-CD 3.41Å; E60-R68 IonicContact OE1-CZ 2.7Å; E60-R68 IonicContact OE1-NE 3.25Å; E60-R68 IonicContact OE1-NH1 3.56Å; E60-R68 PolarHBondContact OE1-NH1 3.21Å; S66-R68 PolarHBondContact O-N 3.17Å; S66-R68 PolarHBondContact OG-N 3.2Å; R68-W71 PolarHBondContact O-N 2.81Å; R68-A72 PolarHBondContact O-N 3.07Å
69	K	82.1	Confident	77.8	Confident	18 Å²	18	73.1 Å²	73.1	8%	0.078	34%	0.341	C	S	.	.	H	α-helix	trans	-63.2	-43.8	169	-73.2	-167.6	-178.4	-176.3	0	111.3	I57 P58 S66 W71 A72 F73 E291 Y295	I57-K69 HydrophobicContact CG2-CG 4.34Å; P58-K69 HydrophobicContact CG-CG 4.26Å; P58-K69 WeakPolarHBondContact O-CE 3.4Å; S66-K69 PolarHBondContact O-N 2.85Å; S66-K69 PolarHBondContact OG-N 3.44Å; K69-W71 PolarHBondContact O-N 2.92Å; K69-A72 WeakPolarHBondContact O-CA 3.35Å; K69-A72 WeakPolarHBondContact O-CB 3.35Å; K69-A72 PolarHBondContact O-N 3.08Å; K69-A72 VanDerWaalsContact O-N 3.08Å; K69-F73 VanDerWaalsContact O-CD2 3.29Å; K69-F73 WeakPolarHBondContact O-CD2 3.12Å; K69-F73 PolarHBondContact O-N 3.16Å; K69-E291 WeakPolarHBondContact CD-OE1 3.41Å; K69-E291 IonicContact NZ-OE1 3.56Å; K69-E291 PolarHBondContact NZ-OE1 3.12Å; K69-E291 IonicContact NZ-OE2 2.66Å; K69-E291 PolarHBondContact NZ-OE2 3.06Å; K69-Y295 HydrophobicContact CB-CE1 4.22Å; K69-Y295 HydrophobicContact CB-CE2 3.87Å; K69-Y295 HydrophobicContact CD-CE2 4.05Å
70	L	85.8	Confident	79.2	Confident	20 Å²	20	64 Å²	64	11%	0.105	30%	0.298	C	S	.	.	H	α-helix	trans	-55.1	-50.9	175.4	179	64.4	0	0	0	110.7	F65 S66 F67 A72 F73 T74 Y295 I298	F65-L70 HydrophobicContact CE2-CD2 4.49Å; F65-L70 HydrophobicContact CZ-CD2 4Å; S66-L70 PolarHBondContact O-N 3.23Å; F67-L70 PolarHBondContact O-N 3.04Å; L70-A72 VanDerWaalsContact C-N 3.28Å; L70-A72 PolarHBondContact O-N 2.88Å; L70-F73 CarbonylContact O-C 3.59Å; L70-F73 WeakPolarHBondContact O-CA 3.4Å; L70-F73 PolarHBondContact O-N 3.5Å; L70-T74 PolarHBondContact O-N 3.01Å; L70-T74 PolarHBondContact O-OG1 2.97Å; L70-Y295 HydrophobicContact CB-CD1 3.97Å; L70-Y295 HydrophobicContact CB-CE1 4.1Å; L70-Y295 HydrophobicContact CD1-CD1 4Å; L70-I298 HydrophobicContact CD1-CG2 4.12Å
71	W	85.6	Confident	80.6	Confident	182 Å²	182	61.2 Å²	61.2	69%	0.689	29%	0.285	S	S	*	.	H	α-helix	trans	-61.4	-32.5	176.7	-173	-100.8	0	0	0	113.5	F67 R68 K69 R205	F67-W71 WeakPolarHBondContact O-CB 3.49Å; F67-W71 PolarHBondContact O-N 3.08Å; R68-W71 PolarHBondContact O-N 2.81Å; K69-W71 PolarHBondContact O-N 2.92Å; W71-R205 PolarHBondContact O-NH2 2.99Å
72	A	83	Confident	82.4	Confident	9 Å²	9	52.8 Å²	52.8	7%	0.074	25%	0.245	C	C	.	.	H	α-helix	trans	-64.3	-39.3	172	0	0	0	0	0	112	P58 R68 K69 L70 R205 R279	P58-A72 VanDerWaalsContact CD-CB 3.5Å; P58-A72 HydrophobicContact CG-CB 4.22Å; R68-A72 PolarHBondContact O-N 3.07Å; K69-A72 WeakPolarHBondContact O-CA 3.35Å; K69-A72 WeakPolarHBondContact O-CB 3.35Å; K69-A72 PolarHBondContact O-N 3.08Å; K69-A72 VanDerWaalsContact O-N 3.08Å; L70-A72 VanDerWaalsContact C-N 3.28Å; L70-A72 PolarHBondContact O-N 2.88Å; A72-R205 PolarHBondContact O-NH2 3.49Å; A72-R279 PolarHBondContact O-NE 3.31Å
73	F	84.1	Confident	84.1	Confident	2 Å²	2	42.5 Å²	42.5	1%	0.009	21%	0.205	C	C	.	.	H	α-helix	trans	-73.3	-43.5	173.7	-79.1	-76.1	0	0	0	112.9	I57 K69 L70 G75 P76 R279 V281 A292 Y295 F296	I57-F73 HydrophobicContact CD1-CE1 3.9Å; I57-F73 HydrophobicContact CD1-CE2 3.88Å; I57-F73 HydrophobicContact CD1-CZ 3.3Å; I57-F73 HydrophobicContact CG1-CE2 4.4Å; I57-F73 HydrophobicContact CG1-CZ 4.17Å; I57-F73 HydrophobicContact CG2-CE2 4.35Å; K69-F73 VanDerWaalsContact O-CD2 3.29Å; K69-F73 WeakPolarHBondContact O-CD2 3.12Å; K69-F73 PolarHBondContact O-N 3.16Å; L70-F73 CarbonylContact O-C 3.59Å; L70-F73 WeakPolarHBondContact O-CA 3.4Å; L70-F73 PolarHBondContact O-N 3.5Å; F73-G75 PolarHBondContact O-N 3.03Å; F73-P76 VanDerWaalsContact O-CD 3.27Å; F73-P76 WeakPolarHBondContact O-CD 3.3Å; F73-R279 HydrophobicContact CD1-CB 4.42Å; F73-R279 HydrophobicContact CD1-CG 4.14Å; F73-R279 HydrophobicContact CE1-CB 4.37Å; F73-R279 PolarHBondContact O-NE 3.26Å; F73-R279 VanDerWaalsContact O-NE 3.17Å; F73-R279 PolarHBondContact O-NH2 3.46Å; F73-R279 VanDerWaalsContact O-NH2 3.17Å; F73-V281 HydrophobicContact CE1-CG2 4.4Å; F73-A292 HydrophobicContact CE1-CB 3.71Å; F73-A292 HydrophobicContact CZ-CB 3.7Å; F73-Y295 HydrophobicContact CD2-CD1 4.48Å; F73-Y295 AromaticContact CD2-CD2 3.56Å; F73-Y295 HydrophobicContact CD2-CD2 3.56Å; F73-Y295 HydrophobicContact CD2-CE2 4.45Å; F73-Y295 AromaticContact CD2-CG 3.58Å; F73-Y295 HydrophobicContact CD2-CG 3.58Å; F73-Y295 AromaticContact CE2-CD2 3.42Å; F73-Y295 HydrophobicContact CE2-CD2 3.42Å; F73-Y295 VanDerWaalsContact CE2-CD2 3.42Å; F73-Y295 HydrophobicContact CE2-CE2 4.21Å; F73-Y295 AromaticContact CE2-CG 3.94Å; F73-Y295 HydrophobicContact CE2-CG 3.94Å; F73-Y295 HydrophobicContact CG-CG 4.31Å; F73-Y295 HydrophobicContact CZ-CD2 4.36Å; F73-F296 HydrophobicContact CD1-CD1 4.17Å; F73-F296 HydrophobicContact CD1-CD2 4.14Å; F73-F296 AromaticContact CD1-CE1 3.77Å; F73-F296 HydrophobicContact CD1-CE1 3.77Å; F73-F296 AromaticContact CD1-CE2 3.75Å; F73-F296 HydrophobicContact CD1-CE2 3.75Å; F73-F296 HydrophobicContact CD1-CG 4.36Å; F73-F296 AromaticContact CD1-CZ 3.58Å; F73-F296 HydrophobicContact CD1-CZ 3.58Å; F73-F296 HydrophobicContact CE1-CD2 4.21Å; F73-F296 AromaticContact CE1-CE2 3.7Å; F73-F296 HydrophobicContact CE1-CE2 3.7Å; F73-F296 AromaticContact CE1-CZ 3.91Å; F73-F296 HydrophobicContact CE1-CZ 3.91Å
74	T	87.8	Confident	85.8	Confident	26 Å²	26	39.5 Å²	39.5	16%	0.16	18%	0.184	C	C	.	.			trans	-45.7	126.5	-177.2	-61	0	0	0	0	113	L70 F78 R205 R279 E299	L70-T74 PolarHBondContact O-N 3.01Å; L70-T74 PolarHBondContact O-OG1 2.97Å; T74-F78 HydrophobicContact CG2-CD2 3.91Å; T74-F78 HydrophobicContact CG2-CE2 3.83Å; T74-R205 PolarHBondContact O-NH1 3.41Å; T74-R279 PolarHBondContact O-NH2 2.97Å; T74-E299 WeakPolarHBondContact CA-OE1 3.42Å
75	G	87.5	Confident	87.3	Confident	3 Å²	3	34.3 Å²	34.3	3%	0.031	15%	0.148	C	C	.	.	S	Bend	trans	153.2	-71.7	-177.8	0	0	0	0	0	111.1	F73 G77 F78 L79 E208 E299	F73-G75 PolarHBondContact O-N 3.03Å; G75-G77 VanDerWaalsContact C-N 3.3Å; G75-G77 PolarHBondContact O-N 3.22Å; G75-F78 PolarHBondContact O-N 3.23Å; G75-L79 WeakPolarHBondContact O-CD1 3.38Å; G75-L79 PolarHBondContact O-N 3.41Å; G75-E208 WeakPolarHBondContact CA-OE1 3.41Å; G75-E299 WeakPolarHBondContact CA-OE1 3.37Å; G75-E299 PolarHBondContact N-OE1 3.27Å
76	P	89.1	Confident	88	Confident	1 Å²	1	31 Å²	31	1%	0.006	13%	0.134	C	C	.	.	H	α-helix	trans	-52.7	-36.4	-175	-34.3	43	0	0	0	116.3	F73 M80 L275 F296	F73-P76 VanDerWaalsContact O-CD 3.27Å; F73-P76 WeakPolarHBondContact O-CD 3.3Å; P76-M80 WeakPolarHBondContact O-CB 3.32Å; P76-M80 PolarHBondContact O-N 3.47Å; P76-L275 HydrophobicContact CB-CB 3.81Å; P76-L275 HydrophobicContact CG-CB 4.39Å; P76-F296 HydrophobicContact CB-CE1 4.25Å; P76-F296 HydrophobicContact CG-CE1 3.99Å
77	G	91	Very high	88.3	Confident	0 Å²	0	30.3 Å²	30.3	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-70.5	-36.3	177.4	0	0	0	0	0	112.9	G75 M80 S81 E299 A303	G75-G77 VanDerWaalsContact C-N 3.3Å; G75-G77 PolarHBondContact O-N 3.22Å; G77-M80 PolarHBondContact O-N 3.25Å; G77-S81 WeakPolarHBondContact O-CB 3.19Å; G77-S81 PolarHBondContact O-N 3.1Å; G77-E299 WeakPolarHBondContact CA-OE1 3.28Å; G77-E299 PolarHBondContact N-OE1 3.4Å; G77-A303 VanDerWaalsContact O-CB 3.3Å; G77-A303 WeakPolarHBondContact O-CB 3.39Å
78	F	90.9	Very high	88.5	Confident	49 Å²	49	22.7 Å²	22.7	22%	0.215	10%	0.096	C	C	.	.	H	α-helix	trans	-73.6	-33.8	174.3	-76.6	-84.9	0	0	0	112.6	T74 G75 M80 S81 I215 I302 A303	T74-F78 HydrophobicContact CG2-CD2 3.91Å; T74-F78 HydrophobicContact CG2-CE2 3.83Å; G75-F78 PolarHBondContact O-N 3.23Å; F78-M80 VanDerWaalsContact C-N 3.35Å; F78-S81 PolarHBondContact O-N 3.17Å; F78-S81 PolarHBondContact O-OG 2.96Å; F78-I215 HydrophobicContact CB-CD1 4.24Å; F78-I215 HydrophobicContact CD1-CD1 4.06Å; F78-I302 HydrophobicContact CZ-CG2 4.09Å; F78-A303 HydrophobicContact CD1-CB 3.99Å; F78-A303 HydrophobicContact CD2-CB 4.22Å; F78-A303 HydrophobicContact CE1-CB 4.19Å; F78-A303 HydrophobicContact CE2-CB 4.4Å; F78-A303 HydrophobicContact CG-CB 4.02Å; F78-A303 HydrophobicContact CZ-CB 4.4Å
79	L	89.9	Confident	89	Confident	4 Å²	4	15.3 Å²	15.3	2%	0.021	7%	0.068	C	C	.	.	H	α-helix	trans	-66.6	-38.3	170.6	-89.3	66.4	0	0	0	111.5	G75 L207 E208 F211 L275 T389	G75-L79 WeakPolarHBondContact O-CD1 3.38Å; G75-L79 PolarHBondContact O-N 3.41Å; L79-L207 HydrophobicContact CD2-CD2 4.26Å; L79-E208 HydrophobicContact CD1-CB 4.45Å; L79-E208 HydrophobicContact CD1-CG 3.92Å; L79-F211 HydrophobicContact CD1-CB 4.13Å; L79-F211 HydrophobicContact CD1-CD2 3.54Å; L79-F211 HydrophobicContact CD1-CE2 4.19Å; L79-F211 HydrophobicContact CD1-CG 4.14Å; L79-F211 HydrophobicContact CD2-CD2 4.05Å; L79-F211 HydrophobicContact CD2-CE2 3.85Å; L79-F211 HydrophobicContact CG-CD2 3.54Å; L79-F211 HydrophobicContact CG-CE2 3.68Å; L79-F211 HydrophobicContact CG-CG 4.27Å; L79-L275 HydrophobicContact CB-CD1 3.57Å; L79-L275 HydrophobicContact CD2-CD1 4.28Å; L79-L275 HydrophobicContact CD2-CD2 3.83Å; L79-T389 WeakPolarHBondContact O-CG2 3.36Å
80	M	92	Very high	89.5	Confident	0 Å²	0	14.6 Å²	14.6	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-67.3	-36	174	172.2	-83.6	-62.6	0	0	112.6	P76 G77 F78 I82 A83 Y84 Q119 N268 H272 L304	P76-M80 WeakPolarHBondContact O-CB 3.32Å; P76-M80 PolarHBondContact O-N 3.47Å; G77-M80 PolarHBondContact O-N 3.25Å; F78-M80 VanDerWaalsContact C-N 3.35Å; M80-I82 PolarHBondContact O-N 3.08Å; M80-A83 PolarHBondContact O-N 3.5Å; M80-Y84 HydrophobicContact SD-CD2 4.31Å; M80-Y84 HydrophobicContact SD-CE2 3.75Å; M80-Q119 HydrophobicContact CE-CB 4.27Å; M80-Q119 HydrophobicContact CE-CG 4.38Å; M80-Q119 HydrophobicContact CG-CG 4.23Å; M80-Q119 HydrophobicContact SD-CB 4.22Å; M80-Q119 HydrophobicContact SD-CG 3.67Å; M80-N268 WeakPolarHBondContact CG-OD1 3.21Å; M80-N268 PolarHBondContact O-ND2 3.36Å; M80-N268 PolarHBondContact O-OD1 2.85Å; M80-H272 HydrophobicContact CB-CB 4.09Å; M80-H272 HydrophobicContact CG-CB 3.76Å; M80-L304 HydrophobicContact CE-CD1 3.87Å; M80-L304 HydrophobicContact CE-CD2 4.28Å; M80-L304 HydrophobicContact CE-CG 3.89Å; M80-L304 HydrophobicContact SD-CD1 4.05Å; M80-L304 HydrophobicContact SD-CD2 3.83Å; M80-L304 HydrophobicContact SD-CG 4.08Å
81	S	92.9	Very high	89.7	Confident	1 Å²	1	13.6 Å²	13.6	1%	0.007	6%	0.06	C	C	.	.	T	Hydrogen-bonded Turn	trans	-78	0.2	-177.2	81.4	0	0	0	0	114.8	G77 F78 S307	G77-S81 WeakPolarHBondContact O-CB 3.19Å; G77-S81 PolarHBondContact O-N 3.1Å; F78-S81 PolarHBondContact O-N 3.17Å; F78-S81 PolarHBondContact O-OG 2.96Å; S81-S307 WeakPolarHBondContact CB-OG 3.18Å; S81-S307 PolarHBondContact O-OG 2.94Å; S81-S307 PolarHBondContact OG-OG 3.04Å
82	I	90.6	Very high	89.9	Confident	0 Å²	0	5.1 Å²	5.1	0%	0	3%	0.028	C	C	.	.	T	Hydrogen-bonded Turn	trans	-75.8	-38.2	171.6	-81.6	162.6	0	0	0	111.8	M80 Y84 L85 D86 F211 I215 S385 T389	M80-I82 PolarHBondContact O-N 3.08Å; I82-Y84 PolarHBondContact O-N 3.07Å; I82-L85 CarbonylContact O-C 3.6Å; I82-L85 WeakPolarHBondContact O-CA 3.17Å; I82-L85 PolarHBondContact O-N 3.49Å; I82-D86 PolarHBondContact O-N 3Å; I82-F211 HydrophobicContact CD1-CB 3.79Å; I82-F211 HydrophobicContact CD1-CD1 3.17Å; I82-F211 HydrophobicContact CD1-CE1 3.77Å; I82-F211 HydrophobicContact CD1-CG 3.7Å; I82-I215 HydrophobicContact CD1-CD1 4.08Å; I82-I215 HydrophobicContact CD1-CG1 4.25Å; I82-I215 HydrophobicContact CG1-CD1 3.87Å; I82-I215 HydrophobicContact CG1-CG1 3.88Å; I82-S385 WeakPolarHBondContact CG2-OG 3.42Å; I82-T389 HydrophobicContact CB-CG2 4.21Å; I82-T389 HydrophobicContact CG2-CG2 3.92Å
83	A	88.7	Confident	90.4	Very high	0 Å²	0	4.7 Å²	4.7	0%	0	3%	0.025	C	C	.	.	T	Hydrogen-bonded Turn	trans	-79.9	40.5	170.9	0	0	0	0	0	111.9	M80 M265 N268	M80-A83 PolarHBondContact O-N 3.5Å; A83-M265 HydrophobicContact CB-SD 3.74Å; A83-N268 HydrophobicContact CB-CB 4.04Å; A83-N268 WeakPolarHBondContact CB-ND2 3.18Å; A83-N268 PolarHBondContact O-ND2 3.27Å
84	Y	91.8	Very high	90.8	Very high	4 Å²	4	4.6 Å²	4.6	2%	0.016	2%	0.024	C	C	.	.	T	Hydrogen-bonded Turn	trans	-136.4	-0.8	164.3	-74.9	-103.1	0	0	0	110.4	M80 I82 N89 G115 Q119 V263 N268 L304 N311	M80-Y84 HydrophobicContact SD-CD2 4.31Å; M80-Y84 HydrophobicContact SD-CE2 3.75Å; I82-Y84 PolarHBondContact O-N 3.07Å; Y84-N89 PolarHBondContact O-ND2 3.01Å; Y84-N89 PolarHBondContact O-OD1 3.45Å; Y84-G115 WeakPolarHBondContact OH-CA 3.42Å; Y84-Q119 HydrophobicContact CE2-CG 4.47Å; Y84-V263 HydrophobicContact CD1-CG1 3.96Å; Y84-V263 WeakPolarHBondContact CD1-O 2.99Å; Y84-V263 HydrophobicContact CE1-CG1 3.79Å; Y84-V263 WeakPolarHBondContact CE1-O 3.06Å; Y84-V263 VanDerWaalsContact CZ-O 3.3Å; Y84-V263 PolarHBondContact OH-O 2.84Å; Y84-N268 WeakPolarHBondContact CE2-ND2 3.41Å; Y84-L304 HydrophobicContact CD1-CD2 3.75Å; Y84-L304 HydrophobicContact CD2-CD2 3.39Å; Y84-L304 HydrophobicContact CE1-CD2 3.8Å; Y84-L304 HydrophobicContact CE2-CD2 3.46Å; Y84-L304 VanDerWaalsContact CE2-CD2 3.46Å; Y84-L304 HydrophobicContact CG-CD2 3.57Å; Y84-N311 PolarHBondContact O-ND2 3.41Å; Y84-N311 PolarHBondContact O-OD1 3.47Å
85	L	93.3	Very high	90.9	Very high	1 Å²	1	4.4 Å²	4.4	1%	0.005	2%	0.021	C	C	.	.	S	Bend	trans	-137	13.2	-172	-64	176.6	0	0	0	111.1	I82 I90 I215 M218 S307 I310 N311 A382	I82-L85 CarbonylContact O-C 3.6Å; I82-L85 WeakPolarHBondContact O-CA 3.17Å; I82-L85 PolarHBondContact O-N 3.49Å; L85-I90 WeakPolarHBondContact O-CD1 3.24Å; L85-I215 HydrophobicContact CD1-CG2 4.38Å; L85-M218 HydrophobicContact CB-CE 3.97Å; L85-M218 HydrophobicContact CB-SD 4.09Å; L85-M218 HydrophobicContact CD1-CE 3.95Å; L85-S307 WeakPolarHBondContact CD1-OG 3.3Å; L85-I310 HydrophobicContact CD1-CD1 3.81Å; L85-I310 HydrophobicContact CD2-CB 3.74Å; L85-I310 HydrophobicContact CD2-CD1 3.96Å; L85-I310 HydrophobicContact CD2-CG1 4.45Å; L85-I310 HydrophobicContact CD2-CG2 3.71Å; L85-N311 WeakPolarHBondContact CD2-OD1 3.46Å; L85-A382 WeakPolarHBondContact O-CB 3.5Å
86	D	91.6	Very high	91	Very high	1 Å²	1	4.2 Å²	4.2	1%	0.005	2%	0.02	C	C	.	.	S	Bend	trans	-72.4	164.1	174.7	62.9	-80.7	0	0	0	111.1	I82 G88 N89 I90 M265	I82-D86 PolarHBondContact O-N 3Å; D86-G88 VanDerWaalsContact C-N 3.26Å; D86-G88 PolarHBondContact O-N 2.93Å; D86-G88 VanDerWaalsContact OD2-CA 3.29Å; D86-G88 WeakPolarHBondContact OD2-CA 3.5Å; D86-G88 PolarHBondContact OD2-N 3.12Å; D86-N89 PolarHBondContact O-N 3.1Å; D86-N89 VanDerWaalsContact OD1-CB 3.24Å; D86-N89 WeakPolarHBondContact OD1-CB 3.45Å; D86-N89 PolarHBondContact OD2-N 3.48Å; D86-I90 WeakPolarHBondContact O-CG1 3.38Å; D86-I90 PolarHBondContact O-N 3.23Å; D86-M265 HydrophobicContact CB-CE 4.46Å; D86-M265 WeakPolarHBondContact OD1-CE 3.33Å; D86-M265 WeakPolarHBondContact OD2-CE 3.49Å
87	P	90.3	Very high	91.1	Very high	0 Å²	0	4.2 Å²	4.2	0%	0	2%	0.019	C	C	.	.	H	α-helix	trans	-58.5	-32.5	179.1	-27.1	37.2	0	0	0	114.5	I90 E91 I356 A382	P87-I90 PolarHBondContact O-N 2.9Å; P87-E91 WeakPolarHBondContact O-CB 3.45Å; P87-E91 PolarHBondContact O-N 2.95Å; P87-I356 HydrophobicContact CB-CD1 3.99Å; P87-A382 HydrophobicContact CG-CB 4.34Å
88	G	88.6	Confident	91	Very high	0 Å²	0	4.9 Å²	4.9	0%	0	3%	0.025	C	C	.	.	H	α-helix	trans	-65.8	-43.2	179.1	0	0	0	0	0	112.4	D86 E91 S92 N443	D86-G88 VanDerWaalsContact C-N 3.26Å; D86-G88 PolarHBondContact O-N 2.93Å; D86-G88 VanDerWaalsContact OD2-CA 3.29Å; D86-G88 WeakPolarHBondContact OD2-CA 3.5Å; D86-G88 PolarHBondContact OD2-N 3.12Å; G88-E91 PolarHBondContact O-N 3.5Å; G88-S92 PolarHBondContact O-N 3.26Å; G88-S92 VanDerWaalsContact O-N 3.08Å; G88-N443 PolarHBondContact O-ND2 2.99Å; G88-N443 PolarHBondContact O-OD1 3.36Å
89	N	91.6	Very high	90.8	Very high	0 Å²	0	4.9 Å²	4.9	0%	0	3%	0.029	C	C	.	.	H	α-helix	trans	-66.2	-47.7	174	-165.6	-53.2	0	0	0	112.3	Y84 D86 E91 S92 D93 A262 V263 N311	Y84-N89 PolarHBondContact O-ND2 3.01Å; Y84-N89 PolarHBondContact O-OD1 3.45Å; D86-N89 PolarHBondContact O-N 3.1Å; D86-N89 VanDerWaalsContact OD1-CB 3.24Å; D86-N89 WeakPolarHBondContact OD1-CB 3.45Å; D86-N89 PolarHBondContact OD2-N 3.48Å; N89-E91 PolarHBondContact O-N 3.34Å; N89-S92 PolarHBondContact O-N 3.11Å; N89-S92 VanDerWaalsContact O-N 3.12Å; N89-D93 PolarHBondContact O-N 3.05Å; N89-A262 HydrophobicContact CB-CB 4.5Å; N89-A262 PolarHBondContact ND2-O 3.45Å; N89-V263 WeakPolarHBondContact ND2-CA 3.38Å; N89-N311 PolarHBondContact OD1-ND2 3.03Å
90	I	92.9	Very high	90.7	Very high	3 Å²	3	4.8 Å²	4.8	2%	0.015	3%	0.029	C	C	.	.	H	α-helix	trans	-59.4	-35.8	176.3	-66.6	168.1	0	0	0	111.7	L85 D86 P87 D93 L94 F222 V314 W375 I379 A382	L85-I90 WeakPolarHBondContact O-CD1 3.24Å; D86-I90 WeakPolarHBondContact O-CG1 3.38Å; D86-I90 PolarHBondContact O-N 3.23Å; P87-I90 PolarHBondContact O-N 2.9Å; I90-D93 PolarHBondContact O-N 2.88Å; I90-L94 WeakPolarHBondContact O-CB 3.34Å; I90-L94 PolarHBondContact O-N 3.36Å; I90-F222 HydrophobicContact CD1-CE2 3.99Å; I90-F222 HydrophobicContact CD1-CZ 3.96Å; I90-V314 HydrophobicContact CG2-CG1 4.21Å; I90-V314 HydrophobicContact CG2-CG2 4.46Å; I90-W375 HydrophobicContact CG2-CH2 3.65Å; I90-W375 HydrophobicContact CG2-CZ2 4.33Å; I90-W375 HydrophobicContact CG2-CZ3 4.41Å; I90-I379 HydrophobicContact CB-CD1 4.49Å; I90-I379 HydrophobicContact CD1-CD1 4.26Å; I90-I379 HydrophobicContact CG2-CD1 3.69Å; I90-A382 HydrophobicContact CD1-CB 3.66Å
91	E	90.8	Very high	90.6	Very high	0 Å²	0	4.9 Å²	4.9	0%	0	3%	0.03	C	C	.	.	H	α-helix	trans	-69.7	-41.4	174.9	-169.9	133.4	-123.8	0	0	112.7	P87 G88 N89 D93 L94 Q95 D355 I356 N439	P87-E91 WeakPolarHBondContact O-CB 3.45Å; P87-E91 PolarHBondContact O-N 2.95Å; G88-E91 PolarHBondContact O-N 3.5Å; N89-E91 PolarHBondContact O-N 3.34Å; E91-D93 VanDerWaalsContact C-N 3.29Å; E91-D93 PolarHBondContact O-N 3.32Å; E91-L94 PolarHBondContact O-N 2.72Å; E91-Q95 WeakPolarHBondContact O-CB 3.41Å; E91-Q95 VanDerWaalsContact O-CG 3.29Å; E91-Q95 WeakPolarHBondContact O-CG 3.48Å; E91-Q95 PolarHBondContact O-N 3.13Å; E91-D355 WeakPolarHBondContact OE1-CA 3.42Å; E91-D355 WeakPolarHBondContact OE1-CB 3.14Å; E91-I356 HydrophobicContact CB-CD1 4.11Å; E91-I356 HydrophobicContact CB-CG1 4.03Å; E91-I356 HydrophobicContact CG-CG1 4.3Å; E91-I356 PolarHBondContact OE1-N 2.84Å; E91-N439 WeakPolarHBondContact CB-ND2 3.32Å; E91-N439 WeakPolarHBondContact CG-ND2 3.1Å; E91-N439 WeakPolarHBondContact OE2-CB 3.45Å; E91-N439 PolarHBondContact OE2-ND2 3.23Å
92	S	89.9	Confident	90.5	Very high	3 Å²	3	5.9 Å²	5.9	2%	0.021	3%	0.034	C	C	.	.	H	α-helix	trans	-63.1	-36.8	172.9	-170.5	0	0	0	0	112.1	G88 N89 S96 G258 I259	G88-S92 PolarHBondContact O-N 3.26Å; G88-S92 VanDerWaalsContact O-N 3.08Å; N89-S92 PolarHBondContact O-N 3.11Å; N89-S92 VanDerWaalsContact O-N 3.12Å; S92-S96 WeakPolarHBondContact O-CB 3.2Å; S92-S96 PolarHBondContact O-N 3.33Å; S92-G258 VanDerWaalsContact OG-C 3.23Å; S92-I259 PolarHBondContact OG-N 3.25Å
93	D	92.6	Very high	90.4	Very high	1 Å²	1	9 Å²	9	1%	0.005	5%	0.048	C	C	.	.	H	α-helix	trans	-69.6	-47.8	177.6	-90.4	-15.4	0	0	0	112.1	N89 I90 E91 Q95 S96 G97 N311 V314 V315	N89-D93 PolarHBondContact O-N 3.05Å; I90-D93 PolarHBondContact O-N 2.88Å; E91-D93 VanDerWaalsContact C-N 3.29Å; E91-D93 PolarHBondContact O-N 3.32Å; D93-Q95 VanDerWaalsContact C-N 3.31Å; D93-Q95 PolarHBondContact O-N 2.93Å; D93-S96 PolarHBondContact O-N 3.47Å; D93-S96 PolarHBondContact O-OG 2.98Å; D93-G97 PolarHBondContact O-N 3.49Å; D93-N311 WeakPolarHBondContact OD2-CA 3.24Å; D93-N311 WeakPolarHBondContact OD2-CB 3.4Å; D93-N311 VanDerWaalsContact OD2-CG 3.25Å; D93-N311 PolarHBondContact OD2-ND2 3.3Å; D93-V314 HydrophobicContact CB-CB 4.38Å; D93-V314 HydrophobicContact CB-CG1 3.95Å; D93-V315 HydrophobicContact CB-CG2 3.57Å; D93-V315 VanDerWaalsContact CG-CG2 3.47Å; D93-V315 WeakPolarHBondContact OD1-CG2 3.5Å
94	L	92.1	Very high	90.5	Very high	0 Å²	0	9 Å²	9	0%	0	5%	0.048	C	C	.	.	H	α-helix	trans	-63.7	-38.1	-179.7	80.1	87.3	0	0	0	111.6	I90 E91 G97 A98 V314 F318 V354 I356 W375	I90-L94 WeakPolarHBondContact O-CB 3.34Å; I90-L94 PolarHBondContact O-N 3.36Å; E91-L94 PolarHBondContact O-N 2.72Å; L94-G97 PolarHBondContact O-N 3.04Å; L94-A98 PolarHBondContact O-N 3.26Å; L94-V314 HydrophobicContact CB-CG1 3.99Å; L94-F318 HydrophobicContact CB-CB 4.24Å; L94-F318 HydrophobicContact CB-CD1 3.88Å; L94-F318 HydrophobicContact CB-CD2 3.64Å; L94-F318 HydrophobicContact CB-CE1 4.19Å; L94-F318 HydrophobicContact CB-CE2 3.97Å; L94-F318 HydrophobicContact CB-CG 3.62Å; L94-F318 HydrophobicContact CB-CZ 4.24Å; L94-F318 HydrophobicContact CD1-CD1 4.23Å; L94-F318 HydrophobicContact CD1-CE1 4.34Å; L94-F318 WeakPolarHBondContact O-CB 3.35Å; L94-V354 HydrophobicContact CD1-CB 3.93Å; L94-V354 HydrophobicContact CD1-CG1 3.49Å; L94-V354 VanDerWaalsContact CD1-CG1 3.49Å; L94-I356 HydrophobicContact CD2-CG1 3.89Å; L94-W375 HydrophobicContact CD2-CH2 4.04Å; L94-W375 HydrophobicContact CD2-CZ2 3.86Å
95	Q	90	Very high	90.5	Very high	21 Å²	21	8.9 Å²	8.9	10%	0.098	5%	0.047	C	C	.	.	H	α-helix	trans	-66.7	-42.6	173.6	-73.4	-178.2	4.9	0	0	112.3	E91 D93 G97 A98 V99 V354 D440	E91-Q95 WeakPolarHBondContact O-CB 3.41Å; E91-Q95 VanDerWaalsContact O-CG 3.29Å; E91-Q95 WeakPolarHBondContact O-CG 3.48Å; E91-Q95 PolarHBondContact O-N 3.13Å; D93-Q95 VanDerWaalsContact C-N 3.31Å; D93-Q95 PolarHBondContact O-N 2.93Å; Q95-G97 VanDerWaalsContact C-N 3.27Å; Q95-G97 PolarHBondContact O-N 3.45Å; Q95-A98 PolarHBondContact O-N 3.29Å; Q95-V99 WeakPolarHBondContact O-CB 3.45Å; Q95-V99 WeakPolarHBondContact O-CG2 3.21Å; Q95-V99 PolarHBondContact O-N 3.14Å; Q95-V354 WeakPolarHBondContact CG-O 3.42Å; Q95-V354 PolarHBondContact NE2-O 2.85Å; Q95-D440 PolarHBondContact NE2-OD1 3.45Å; Q95-D440 PolarHBondContact NE2-OD2 3.06Å
96	S	89.9	Confident	90.5	Very high	0 Å²	0	12.1 Å²	12.1	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-59.8	-39.9	177.3	81.1	0	0	0	0	112.1	S92 D93 A100	S92-S96 WeakPolarHBondContact O-CB 3.2Å; S92-S96 PolarHBondContact O-N 3.33Å; D93-S96 PolarHBondContact O-N 3.47Å; D93-S96 PolarHBondContact O-OG 2.98Å; S96-A100 WeakPolarHBondContact O-CB 3.37Å; S96-A100 PolarHBondContact O-N 3.49Å
97	G	90.6	Very high	90.5	Very high	0 Å²	0	13.1 Å²	13.1	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-62	-49.9	172.7	0	0	0	0	0	111.9	D93 L94 Q95 V99 G101 A319	D93-G97 PolarHBondContact O-N 3.49Å; L94-G97 PolarHBondContact O-N 3.04Å; Q95-G97 VanDerWaalsContact C-N 3.27Å; Q95-G97 PolarHBondContact O-N 3.45Å; G97-V99 PolarHBondContact O-N 3.24Å; G97-G101 WeakPolarHBondContact O-CA 3.37Å; G97-G101 PolarHBondContact O-N 2.96Å; G97-A319 WeakPolarHBondContact O-CA 3.33Å
98	A	89	Confident	90.6	Very high	14 Å²	14	13.2 Å²	13.2	12%	0.116	7%	0.065	C	C	.	.	H	α-helix	trans	-64	-40.6	-179.6	0	0	0	0	0	114	L94 Q95 F322 V354	L94-A98 PolarHBondContact O-N 3.26Å; Q95-A98 PolarHBondContact O-N 3.29Å; A98-F322 HydrophobicContact CB-CB 3.92Å; A98-V354 HydrophobicContact CB-CB 4.16Å; A98-V354 HydrophobicContact CB-CG2 3.51Å
99	V	87.5	Confident	90.9	Very high	49 Å²	49	14.9 Å²	14.9	30%	0.297	7%	0.074	S	C	.	.	H	α-helix	trans	-88.1	-28.5	-172.3	175.8	0	0	0	0	113.3	Q95 G97 P251 Q252 Q255	Q95-V99 WeakPolarHBondContact O-CB 3.45Å; Q95-V99 WeakPolarHBondContact O-CG2 3.21Å; Q95-V99 PolarHBondContact O-N 3.14Å; G97-V99 PolarHBondContact O-N 3.24Å; V99-P251 HydrophobicContact CG1-CB 4.15Å; V99-Q252 HydrophobicContact CG1-CG 4.4Å; V99-Q252 PolarHBondContact O-NE2 3.21Å; V99-Q255 HydrophobicContact CB-CG 4.27Å; V99-Q255 HydrophobicContact CG1-CG 4.19Å; V99-Q255 HydrophobicContact CG2-CG 4.47Å
100	A	87.7	Confident	91	Very high	2 Å²	2	19.1 Å²	19.1	2%	0.017	10%	0.096	C	C	.	.	H	α-helix	trans	-127.5	-9.2	-174.5	0	0	0	0	0	114.8	S96 K103 L104 Q252 F323	S96-A100 WeakPolarHBondContact O-CB 3.37Å; S96-A100 PolarHBondContact O-N 3.49Å; A100-K103 WeakPolarHBondContact O-CB 3.2Å; A100-K103 WeakPolarHBondContact O-CG 3.33Å; A100-K103 PolarHBondContact O-N 3.32Å; A100-L104 HydrophobicContact CB-CD1 3.44Å; A100-L104 VanDerWaalsContact CB-CD1 3.44Å; A100-L104 HydrophobicContact CB-CD2 4.43Å; A100-L104 HydrophobicContact CB-CG 3.53Å; A100-Q252 HydrophobicContact CB-CB 4.47Å; A100-Q252 HydrophobicContact CB-CG 3.81Å; A100-F323 VanDerWaalsContact C-CE2 3.49Å
101	G	89.7	Confident	91	Very high	3 Å²	3	19.2 Å²	19.2	3%	0.031	10%	0.097	C	C	.	.	G	3₁₀ helix	trans	61.8	-148.5	-172.6	0	0	0	0	0	111.2	G97 K103 F323	G97-G101 WeakPolarHBondContact O-CA 3.37Å; G97-G101 PolarHBondContact O-N 2.96Å; G101-K103 PolarHBondContact O-N 2.98Å; G101-F323 VanDerWaalsContact N-CD2 3.3Å
102	F	90.6	Very high	91.2	Very high	21 Å²	21	19.7 Å²	19.7	9%	0.092	10%	0.1	C	C	.	.	G	3₁₀ helix	trans	-64	-2.7	179.9	-50.4	-72	0	0	0	115	L104 L105 P231 Q235 V236 G239 A319 E320	F102-L104 PolarHBondContact O-N 3.04Å; F102-L105 HydrophobicContact CB-CD1 4.06Å; F102-L105 HydrophobicContact CD1-CD1 4.05Å; F102-P231 HydrophobicContact CE1-CB 4.16Å; F102-P231 HydrophobicContact CZ-CB 4.17Å; F102-Q235 HydrophobicContact CB-CB 4.5Å; F102-Q235 HydrophobicContact CD2-CB 3.56Å; F102-Q235 HydrophobicContact CD2-CG 4.45Å; F102-Q235 HydrophobicContact CE2-CB 3.91Å; F102-Q235 HydrophobicContact CG-CB 3.99Å; F102-V236 HydrophobicContact CD1-CG2 3.81Å; F102-V236 HydrophobicContact CE1-CG2 3.65Å; F102-G239 WeakPolarHBondContact O-CA 3.27Å; F102-A319 HydrophobicContact CD1-CB 3.93Å; F102-A319 HydrophobicContact CE1-CB 3.69Å; F102-A319 HydrophobicContact CE2-CB 4.32Å; F102-A319 HydrophobicContact CG-CB 4.34Å; F102-A319 HydrophobicContact CZ-CB 3.9Å; F102-E320 HydrophobicContact CZ-CB 4.3Å
103	K	88.9	Confident	91.4	Very high	66 Å²	66	23.7 Å²	23.7	29%	0.287	12%	0.121	S	C	.	.	G	3₁₀ helix	trans	-70.2	-22.6	-171.8	-65	-178.3	-173.7	179.2	0	115.3	A100 G101 W106 S246	A100-K103 WeakPolarHBondContact O-CB 3.2Å; A100-K103 WeakPolarHBondContact O-CG 3.33Å; A100-K103 PolarHBondContact O-N 3.32Å; G101-K103 PolarHBondContact O-N 2.98Å; K103-W106 PolarHBondContact O-NE1 3.26Å; K103-W106 VanDerWaalsContact O-NE1 3.15Å; K103-S246 PolarHBondContact NZ-O 3.04Å
104	L	90.4	Very high	91.4	Very high	1 Å²	1	25 Å²	25	1%	0.005	13%	0.129	C	C	.	.	G	3₁₀ helix	trans	-99.5	-1.5	-176.6	-59.5	179.2	0	0	0	113.6	A100 F102 W106 I107 L108 Q255 A256 I259	A100-L104 HydrophobicContact CB-CD1 3.44Å; A100-L104 VanDerWaalsContact CB-CD1 3.44Å; A100-L104 HydrophobicContact CB-CD2 4.43Å; A100-L104 HydrophobicContact CB-CG 3.53Å; F102-L104 PolarHBondContact O-N 3.04Å; L104-W106 VanDerWaalsContact C-N 3.27Å; L104-W106 PolarHBondContact O-N 3.41Å; L104-I107 HydrophobicContact CD2-CD1 3.87Å; L104-I107 WeakPolarHBondContact O-CA 3.32Å; L104-I107 WeakPolarHBondContact O-CB 3.45Å; L104-I107 PolarHBondContact O-N 2.81Å; L104-L108 PolarHBondContact O-N 3.29Å; L104-Q255 HydrophobicContact CD1-CB 4.03Å; L104-A256 HydrophobicContact CD2-CB 4.07Å; L104-I259 HydrophobicContact CB-CD1 3.7Å; L104-I259 HydrophobicContact CD1-CD1 4.07Å; L104-I259 HydrophobicContact CG-CD1 4.46Å
105	L	92.6	Very high	91.4	Very high	0 Å²	0	25 Å²	25	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-58.8	-32.9	180	-75.5	172.2	0	0	0	113.7	F102 I107 L108 L109 V236 M240 V312 V315	F102-L105 HydrophobicContact CB-CD1 4.06Å; F102-L105 HydrophobicContact CD1-CD1 4.05Å; L105-I107 VanDerWaalsContact C-N 3.29Å; L105-I107 PolarHBondContact O-N 3.49Å; L105-L108 HydrophobicContact CD2-CD2 4.31Å; L105-L108 PolarHBondContact O-N 3.44Å; L105-L109 WeakPolarHBondContact O-CB 3.43Å; L105-L109 PolarHBondContact O-N 2.87Å; L105-V236 HydrophobicContact CD1-CB 4.5Å; L105-V236 HydrophobicContact CD1-CG1 4.07Å; L105-M240 HydrophobicContact CB-CG 3.92Å; L105-M240 HydrophobicContact CD1-CG 4.2Å; L105-V312 HydrophobicContact CD2-CG1 4.48Å; L105-V312 HydrophobicContact CD2-CG2 4.23Å; L105-V315 HydrophobicContact CD2-CB 3.77Å; L105-V315 HydrophobicContact CD2-CG1 3.58Å; L105-V315 HydrophobicContact CD2-CG2 4.38Å; L105-V315 HydrophobicContact CG-CG1 4.05Å
106	W	92.4	Very high	91.7	Very high	70 Å²	70	25 Å²	25	27%	0.265	13%	0.13	S	C	.	.	H	α-helix	trans	-69.1	-26.1	173.1	73	-86.6	0	0	0	112.9	K103 L104 L110 G239 M240 P243	K103-W106 PolarHBondContact O-NE1 3.26Å; K103-W106 VanDerWaalsContact O-NE1 3.15Å; L104-W106 VanDerWaalsContact C-N 3.27Å; L104-W106 PolarHBondContact O-N 3.41Å; W106-L110 HydrophobicContact CZ3-CD2 4.09Å; W106-L110 VanDerWaalsContact O-CB 3.26Å; W106-L110 WeakPolarHBondContact O-CB 3.32Å; W106-L110 PolarHBondContact O-N 2.85Å; W106-G239 WeakPolarHBondContact CB-O 3.43Å; W106-G239 PolarHBondContact N-O 2.92Å; W106-M240 WeakPolarHBondContact CA-O 3.34Å; W106-M240 VanDerWaalsContact CB-O 3.27Å; W106-M240 WeakPolarHBondContact CB-O 3.43Å; W106-P243 HydrophobicContact CD2-CB 3.8Å; W106-P243 HydrophobicContact CE3-CB 3.95Å; W106-P243 HydrophobicContact CG-CB 4.24Å; W106-P243 HydrophobicContact CH2-CB 4.49Å; W106-P243 HydrophobicContact CZ2-CB 4.36Å; W106-P243 HydrophobicContact CZ3-CB 4.29Å
107	I	92.1	Very high	91.8	Very high	22 Å²	22	28.5 Å²	28.5	11%	0.113	15%	0.148	C	C	.	.	H	α-helix	trans	-76.9	-42.6	174.9	-55.1	-169	0	0	0	109.8	L104 L105 L109 L110 A111 A256 V260	L104-I107 HydrophobicContact CD2-CD1 3.87Å; L104-I107 WeakPolarHBondContact O-CA 3.32Å; L104-I107 WeakPolarHBondContact O-CB 3.45Å; L104-I107 PolarHBondContact O-N 2.81Å; L105-I107 VanDerWaalsContact C-N 3.29Å; L105-I107 PolarHBondContact O-N 3.49Å; I107-L109 VanDerWaalsContact C-N 3.33Å; I107-L109 PolarHBondContact O-N 2.89Å; I107-L110 PolarHBondContact O-N 2.67Å; I107-A111 WeakPolarHBondContact O-CB 3.41Å; I107-A111 PolarHBondContact O-N 2.91Å; I107-A256 HydrophobicContact CD1-CB 3.58Å; I107-V260 HydrophobicContact CG2-CG2 4.06Å
108	L	93.4	Very high	92	Very high	1 Å²	1	29 Å²	29	1%	0.005	15%	0.15	C	C	.	.	H	α-helix	trans	-55.9	-47	169.9	173.8	63	0	0	0	111.5	L104 L105 A111 T112 I259 V263 F308 N311 V312 V315	L104-L108 PolarHBondContact O-N 3.29Å; L105-L108 HydrophobicContact CD2-CD2 4.31Å; L105-L108 PolarHBondContact O-N 3.44Å; L108-A111 PolarHBondContact O-N 3.29Å; L108-T112 WeakPolarHBondContact O-CB 3.17Å; L108-T112 PolarHBondContact O-N 2.85Å; L108-T112 PolarHBondContact O-OG1 3.45Å; L108-I259 HydrophobicContact CB-CG2 4.13Å; L108-I259 HydrophobicContact CD1-CG2 4.23Å; L108-V263 HydrophobicContact CD1-CG2 3.77Å; L108-F308 HydrophobicContact CD2-CD2 4.48Å; L108-F308 HydrophobicContact CD2-CE2 4.23Å; L108-F308 HydrophobicContact CG-CD2 4.16Å; L108-F308 HydrophobicContact CG-CE2 3.97Å; L108-N311 HydrophobicContact CD1-CB 4.04Å; L108-N311 HydrophobicContact CD2-CB 3.76Å; L108-N311 HydrophobicContact CG-CB 4.41Å; L108-V312 HydrophobicContact CD2-CG2 4.11Å; L108-V315 HydrophobicContact CD2-CG2 3.94Å
109	L	94.9	Very high	92.2	Very high	36 Å²	36	28.4 Å²	28.4	19%	0.188	15%	0.145	C	C	.	.	H	α-helix	trans	-60.4	-46.4	175.4	175.8	59	0	0	0	111.8	L105 I107 T112 L113 F241 F308	L105-L109 WeakPolarHBondContact O-CB 3.43Å; L105-L109 PolarHBondContact O-N 2.87Å; I107-L109 VanDerWaalsContact C-N 3.33Å; I107-L109 PolarHBondContact O-N 2.89Å; L109-T112 PolarHBondContact O-N 3.36Å; L109-L113 HydrophobicContact CD1-CD1 4Å; L109-L113 HydrophobicContact CD1-CG 4.19Å; L109-L113 HydrophobicContact CG-CD1 4.09Å; L109-L113 WeakPolarHBondContact O-CB 3.44Å; L109-L113 VanDerWaalsContact O-CG 3.26Å; L109-L113 WeakPolarHBondContact O-CG 3.03Å; L109-L113 PolarHBondContact O-N 2.83Å; L109-F241 HydrophobicContact CD2-CD1 4.37Å; L109-F241 HydrophobicContact CD2-CE1 4.14Å; L109-F308 HydrophobicContact CB-CE2 3.78Å; L109-F308 HydrophobicContact CB-CZ 3.79Å; L109-F308 HydrophobicContact CD1-CE1 3.96Å; L109-F308 HydrophobicContact CD1-CE2 4.03Å; L109-F308 HydrophobicContact CD1-CZ 3.63Å; L109-F308 HydrophobicContact CG-CZ 4.2Å
110	L	93.1	Very high	92.6	Very high	89 Å²	89	30 Å²	30	47%	0.466	15%	0.146	S	C	.	.	H	α-helix	trans	-65.8	-42.4	179	-178.5	60.2	0	0	0	112	W106 I107 L113 V114	W106-L110 HydrophobicContact CZ3-CD2 4.09Å; W106-L110 VanDerWaalsContact O-CB 3.26Å; W106-L110 WeakPolarHBondContact O-CB 3.32Å; W106-L110 PolarHBondContact O-N 2.85Å; I107-L110 PolarHBondContact O-N 2.67Å; L110-L113 PolarHBondContact O-N 3.12Å; L110-V114 HydrophobicContact CD1-CG2 4.29Å; L110-V114 WeakPolarHBondContact O-CB 3.38Å; L110-V114 VanDerWaalsContact O-CG2 3.27Å; L110-V114 WeakPolarHBondContact O-CG2 3.36Å; L110-V114 PolarHBondContact O-N 3.02Å
111	A	92.3	Very high	92.9	Very high	4 Å²	4	30.3 Å²	30.3	3%	0.033	15%	0.147	C	C	.	.	H	α-helix	trans	-63.6	-41.9	176.8	0	0	0	0	0	111.1	I107 L108 V114 G115 I259 V260 V263	I107-A111 WeakPolarHBondContact O-CB 3.41Å; I107-A111 PolarHBondContact O-N 2.91Å; L108-A111 PolarHBondContact O-N 3.29Å; A111-V114 PolarHBondContact O-N 3.38Å; A111-G115 PolarHBondContact O-N 2.82Å; A111-I259 HydrophobicContact CB-CG2 4.36Å; A111-V260 HydrophobicContact CB-CG2 4.26Å; A111-V263 HydrophobicContact CB-CB 3.99Å; A111-V263 HydrophobicContact CB-CG1 3.76Å; A111-V263 HydrophobicContact CB-CG2 4.45Å
112	T	94.6	Very high	93.1	Very high	11 Å²	11	30.1 Å²	30.1	7%	0.067	15%	0.146	C	C	.	.	H	α-helix	trans	-66.6	-42.2	175.8	-51.7	0	0	0	0	111.6	L108 L109 G115 L116 L304 F308	L108-T112 WeakPolarHBondContact O-CB 3.17Å; L108-T112 PolarHBondContact O-N 2.85Å; L108-T112 PolarHBondContact O-OG1 3.45Å; L109-T112 PolarHBondContact O-N 3.36Å; T112-G115 PolarHBondContact O-N 3.46Å; T112-L116 WeakPolarHBondContact O-CB 3.37Å; T112-L116 PolarHBondContact O-N 3Å; T112-L304 HydrophobicContact CG2-CB 4.38Å; T112-F308 HydrophobicContact CG2-CB 4.1Å
113	L	94.4	Very high	93.3	Very high	87 Å²	87	29.3 Å²	29.3	46%	0.455	14%	0.143	S	C	.	.	H	α-helix	trans	-61.7	-47.8	175.3	-75.3	170.4	0	0	0	111.2	L109 L110 G115 L116 L117	L109-L113 HydrophobicContact CD1-CD1 4Å; L109-L113 HydrophobicContact CD1-CG 4.19Å; L109-L113 HydrophobicContact CG-CD1 4.09Å; L109-L113 WeakPolarHBondContact O-CB 3.44Å; L109-L113 VanDerWaalsContact O-CG 3.26Å; L109-L113 WeakPolarHBondContact O-CG 3.03Å; L109-L113 PolarHBondContact O-N 2.83Å; L110-L113 PolarHBondContact O-N 3.12Å; L113-G115 VanDerWaalsContact C-N 3.33Å; L113-G115 PolarHBondContact O-N 2.89Å; L113-L116 WeakPolarHBondContact O-CB 3.27Å; L113-L116 PolarHBondContact O-N 3.26Å; L113-L117 VanDerWaalsContact O-CG 3.27Å; L113-L117 WeakPolarHBondContact O-CG 3.33Å; L113-L117 PolarHBondContact O-N 3.29Å
114	V	92.7	Very high	93.5	Very high	29 Å²	29	28.2 Å²	28.2	18%	0.176	14%	0.137	C	C	.	.	H	α-helix	trans	-60.4	-42.9	174.9	168.8	0	0	0	0	111.1	L110 A111 L116 L117 L118 I264 L483	L110-V114 HydrophobicContact CD1-CG2 4.29Å; L110-V114 WeakPolarHBondContact O-CB 3.38Å; L110-V114 VanDerWaalsContact O-CG2 3.27Å; L110-V114 WeakPolarHBondContact O-CG2 3.36Å; L110-V114 PolarHBondContact O-N 3.02Å; A111-V114 PolarHBondContact O-N 3.38Å; V114-L116 PolarHBondContact O-N 3.25Å; V114-L117 WeakPolarHBondContact O-CB 3.27Å; V114-L117 PolarHBondContact O-N 3.44Å; V114-L117 VanDerWaalsContact O-N 3.11Å; V114-L118 HydrophobicContact CG1-CD1 3.93Å; V114-L118 HydrophobicContact CG1-CG 4.38Å; V114-L118 WeakPolarHBondContact O-CB 3.35Å; V114-L118 WeakPolarHBondContact O-CG 2.96Å; V114-L118 PolarHBondContact O-N 2.85Å; V114-I264 HydrophobicContact CB-CD1 4.43Å; V114-I264 HydrophobicContact CG1-CD1 3.84Å; V114-L483 HydrophobicContact CG1-CD1 3.81Å; V114-L483 HydrophobicContact CG1-CD2 3.52Å; V114-L483 HydrophobicContact CG1-CG 4.32Å
115	G	93.3	Very high	93.7	Very high	0 Å²	0	28.1 Å²	28.1	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-54.8	-49.9	172.4	0	0	0	0	0	112.1	Y84 A111 T112 L113 L117 L118 Q119	Y84-G115 WeakPolarHBondContact OH-CA 3.42Å; A111-G115 PolarHBondContact O-N 2.82Å; T112-G115 PolarHBondContact O-N 3.46Å; L113-G115 VanDerWaalsContact C-N 3.33Å; L113-G115 PolarHBondContact O-N 2.89Å; G115-L117 VanDerWaalsContact C-N 3.31Å; G115-L117 PolarHBondContact O-N 3.29Å; G115-L118 WeakPolarHBondContact O-CB 3.16Å; G115-L118 PolarHBondContact O-N 2.86Å; G115-Q119 VanDerWaalsContact O-CB 3.28Å; G115-Q119 WeakPolarHBondContact O-CB 3.33Å; G115-Q119 WeakPolarHBondContact O-CG 3.38Å; G115-Q119 PolarHBondContact O-N 3.37Å
116	L	95.2	Very high	93.7	Very high	21 Å²	21	28.2 Å²	28.2	11%	0.11	14%	0.138	C	C	.	.	H	α-helix	trans	-58.3	-38.8	173.8	172.1	64.4	0	0	0	112.5	T112 L113 V114 R120 F297 L304	T112-L116 WeakPolarHBondContact O-CB 3.37Å; T112-L116 PolarHBondContact O-N 3Å; L113-L116 WeakPolarHBondContact O-CB 3.27Å; L113-L116 PolarHBondContact O-N 3.26Å; V114-L116 PolarHBondContact O-N 3.25Å; L116-R120 VanDerWaalsContact O-CB 3.31Å; L116-R120 WeakPolarHBondContact O-CB 3.28Å; L116-R120 PolarHBondContact O-N 2.99Å; L116-F297 HydrophobicContact CD1-CE2 4.18Å; L116-F297 HydrophobicContact CG-CE2 4.32Å; L116-L304 HydrophobicContact CB-CD1 3.76Å; L116-L304 HydrophobicContact CD1-CD1 3.98Å; L116-L304 HydrophobicContact CG-CD1 4.47Å
117	L	93.4	Very high	93.7	Very high	72 Å²	72	25.3 Å²	25.3	38%	0.377	13%	0.127	S	C	.	.	H	α-helix	trans	-67.3	-41.4	176.6	-55	-160.8	0	0	0	111.8	L113 V114 G115 R120 L121 W476	L113-L117 VanDerWaalsContact O-CG 3.27Å; L113-L117 WeakPolarHBondContact O-CG 3.33Å; L113-L117 PolarHBondContact O-N 3.29Å; V114-L117 WeakPolarHBondContact O-CB 3.27Å; V114-L117 PolarHBondContact O-N 3.44Å; V114-L117 VanDerWaalsContact O-N 3.11Å; G115-L117 VanDerWaalsContact C-N 3.31Å; G115-L117 PolarHBondContact O-N 3.29Å; L117-R120 WeakPolarHBondContact O-CB 3.39Å; L117-R120 PolarHBondContact O-N 3.45Å; L117-L121 PolarHBondContact O-N 3.35Å; L117-W476 HydrophobicContact CB-CH2 4.01Å; L117-W476 HydrophobicContact CB-CZ3 3.95Å; L117-W476 HydrophobicContact CD1-CH2 3.82Å; L117-W476 HydrophobicContact CD1-CZ3 3.99Å; L117-W476 HydrophobicContact CD2-CH2 4.09Å; L117-W476 HydrophobicContact CG-CH2 4.15Å; L117-W476 HydrophobicContact CG-CZ3 4.44Å
118	L	93.1	Very high	93.8	Very high	11 Å²	11	25.3 Å²	25.3	6%	0.058	13%	0.128	C	C	.	.	H	α-helix	trans	-67.3	-44.7	176.6	-75.5	172.2	0	0	0	111.9	V114 G115 R120 L121 A122 I264 M269 L454 L483	V114-L118 HydrophobicContact CG1-CD1 3.93Å; V114-L118 HydrophobicContact CG1-CG 4.38Å; V114-L118 WeakPolarHBondContact O-CB 3.35Å; V114-L118 WeakPolarHBondContact O-CG 2.96Å; V114-L118 PolarHBondContact O-N 2.85Å; G115-L118 WeakPolarHBondContact O-CB 3.16Å; G115-L118 PolarHBondContact O-N 2.86Å; L118-R120 VanDerWaalsContact C-N 3.29Å; L118-R120 PolarHBondContact O-N 3.43Å; L118-L121 WeakPolarHBondContact O-CA 3.32Å; L118-L121 WeakPolarHBondContact O-CB 3.45Å; L118-L121 PolarHBondContact O-N 3.19Å; L118-A122 PolarHBondContact O-N 3.2Å; L118-A122 VanDerWaalsContact O-N 3.09Å; L118-I264 HydrophobicContact CD1-CD1 4.19Å; L118-I264 HydrophobicContact CD1-CG2 3.54Å; L118-M269 HydrophobicContact CB-CE 3.62Å; L118-M269 HydrophobicContact CD2-CE 4.3Å; L118-M269 HydrophobicContact CG-CE 4.48Å; L118-M269 VanDerWaalsContact O-CE 3.32Å; L118-M269 WeakPolarHBondContact O-CE 3.46Å; L118-L454 HydrophobicContact CD1-CD1 3.63Å; L118-L454 HydrophobicContact CD2-CD1 3.69Å; L118-L454 HydrophobicContact CD2-CG 3.98Å; L118-L454 HydrophobicContact CG-CD1 4.33Å; L118-L483 HydrophobicContact CD1-CD2 4.09Å; L118-L483 HydrophobicContact CD2-CD2 3.94Å; L118-L483 HydrophobicContact CG-CD2 4.08Å
119	Q	94.8	Very high	93.6	Very high	2 Å²	2	26.7 Å²	26.7	1%	0.009	14%	0.137	C	C	.	.	H	α-helix	trans	-64.7	-33.4	176.1	-72.2	-68.9	6.6	0	0	111.9	M80 Y84 G115 L121 A122 A123 N268 H272	M80-Q119 HydrophobicContact CE-CB 4.27Å; M80-Q119 HydrophobicContact CE-CG 4.38Å; M80-Q119 HydrophobicContact CG-CG 4.23Å; M80-Q119 HydrophobicContact SD-CB 4.22Å; M80-Q119 HydrophobicContact SD-CG 3.67Å; Y84-Q119 HydrophobicContact CE2-CG 4.47Å; G115-Q119 VanDerWaalsContact O-CB 3.28Å; G115-Q119 WeakPolarHBondContact O-CB 3.33Å; G115-Q119 WeakPolarHBondContact O-CG 3.38Å; G115-Q119 PolarHBondContact O-N 3.37Å; Q119-L121 VanDerWaalsContact C-N 3.3Å; Q119-L121 PolarHBondContact O-N 3.07Å; Q119-A122 WeakPolarHBondContact O-CB 3.28Å; Q119-A122 PolarHBondContact O-N 2.83Å; Q119-A123 PolarHBondContact O-N 3.11Å; Q119-N268 VanDerWaalsContact NE2-CG 3.3Å; Q119-N268 PolarHBondContact NE2-ND2 2.85Å; Q119-H272 PolarHBondContact O-CE1 3.37Å; Q119-H272 PolarHBondContact O-ND1 3.01Å; Q119-H272 PolarHBondContact OE1-ND1 2.93Å
120	R	94.4	Very high	93.3	Very high	81 Å²	81	25.1 Å²	25.1	31%	0.306	13%	0.13	S	C	.	.	H	α-helix	trans	-62.3	-34.6	168.8	-172.7	-170.1	-172.6	-174.3	2.9	112.3	L116 L117 L118 R124 F297	L116-R120 VanDerWaalsContact O-CB 3.31Å; L116-R120 WeakPolarHBondContact O-CB 3.28Å; L116-R120 PolarHBondContact O-N 2.99Å; L117-R120 WeakPolarHBondContact O-CB 3.39Å; L117-R120 PolarHBondContact O-N 3.45Å; L118-R120 VanDerWaalsContact C-N 3.29Å; L118-R120 PolarHBondContact O-N 3.43Å; R120-R124 VanDerWaalsContact O-CB 3.3Å; R120-R124 WeakPolarHBondContact O-CB 3.18Å; R120-R124 WeakPolarHBondContact O-CD 3.47Å; R120-R124 WeakPolarHBondContact O-CG 3.26Å; R120-R124 PolarHBondContact O-N 2.94Å; R120-R124 VanDerWaalsContact O-N 3.07Å; R120-F297 HydrophobicContact CB-CD2 4.1Å; R120-F297 HydrophobicContact CB-CE2 4.43Å; R120-F297 HydrophobicContact CG-CD2 3.68Å; R120-F297 HydrophobicContact CG-CE2 4.21Å; R120-F297 HydrophobicContact CG-CG 4.4Å
121	L	93.8	Very high	93.2	Very high	9 Å²	9	22.1 Å²	22.1	5%	0.047	11%	0.114	C	C	.	.	H	α-helix	trans	-69	-38.3	173.1	-63.6	-177.4	0	0	0	111.4	L117 L118 Q119 R124 L125 I457 T461	L117-L121 PolarHBondContact O-N 3.35Å; L118-L121 WeakPolarHBondContact O-CA 3.32Å; L118-L121 WeakPolarHBondContact O-CB 3.45Å; L118-L121 PolarHBondContact O-N 3.19Å; Q119-L121 VanDerWaalsContact C-N 3.3Å; Q119-L121 PolarHBondContact O-N 3.07Å; L121-R124 PolarHBondContact O-N 3.3Å; L121-L125 PolarHBondContact O-N 2.97Å; L121-I457 HydrophobicContact CB-CG1 4.5Å; L121-T461 HydrophobicContact CB-CG2 4.19Å
122	A	94.8	Very high	93.2	Very high	0 Å²	0	22.2 Å²	22.2	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-61.8	-51.7	175.5	0	0	0	0	0	112.8	L118 Q119 R124 L125 G126 M269 H272 S273 I457	L118-A122 PolarHBondContact O-N 3.2Å; L118-A122 VanDerWaalsContact O-N 3.09Å; Q119-A122 WeakPolarHBondContact O-CB 3.28Å; Q119-A122 PolarHBondContact O-N 2.83Å; A122-R124 VanDerWaalsContact C-N 3.35Å; A122-R124 PolarHBondContact O-N 2.94Å; A122-L125 PolarHBondContact O-N 3.03Å; A122-G126 PolarHBondContact O-N 3.41Å; A122-M269 WeakPolarHBondContact CB-O 3.47Å; A122-H272 HydrophobicContact CB-CB 4.35Å; A122-S273 WeakPolarHBondContact O-CA 3.31Å; A122-S273 WeakPolarHBondContact O-CB 3.34Å; A122-I457 VanDerWaalsContact CA-CD1 3.4Å; A122-I457 HydrophobicContact CB-CD1 3.54Å
123	A	94.4	Very high	93.1	Very high	4 Å²	4	21.7 Å²	21.7	3%	0.033	11%	0.11	C	C	.	.	H	α-helix	trans	-56.5	-47.9	174.7	0	0	0	0	0	111.6	Q119 L125 G126 V127 V276	Q119-A123 PolarHBondContact O-N 3.11Å; A123-L125 VanDerWaalsContact C-N 3.35Å; A123-L125 PolarHBondContact O-N 3.16Å; A123-G126 PolarHBondContact O-N 3.08Å; A123-V127 WeakPolarHBondContact O-CB 3.36Å; A123-V127 VanDerWaalsContact O-CG2 3.26Å; A123-V127 WeakPolarHBondContact O-CG2 3.36Å; A123-V127 PolarHBondContact O-N 3.37Å; A123-V276 HydrophobicContact CB-CG1 3.99Å
124	R	94.4	Very high	93.1	Very high	42 Å²	42	17.5 Å²	17.5	16%	0.158	9%	0.089	C	C	.	.	H	α-helix	trans	-62	-38.8	-179.5	-73.8	174.9	75.2	-120.4	-5.8	112.9	R120 L121 A122 V128 N293 M467 F470 N472	R120-R124 VanDerWaalsContact O-CB 3.3Å; R120-R124 WeakPolarHBondContact O-CB 3.18Å; R120-R124 WeakPolarHBondContact O-CD 3.47Å; R120-R124 WeakPolarHBondContact O-CG 3.26Å; R120-R124 PolarHBondContact O-N 2.94Å; R120-R124 VanDerWaalsContact O-N 3.07Å; L121-R124 PolarHBondContact O-N 3.3Å; A122-R124 VanDerWaalsContact C-N 3.35Å; A122-R124 PolarHBondContact O-N 2.94Å; R124-V128 VanDerWaalsContact O-CB 3.28Å; R124-V128 WeakPolarHBondContact O-CB 3.45Å; R124-V128 WeakPolarHBondContact O-CG2 3.39Å; R124-V128 PolarHBondContact O-N 3.45Å; R124-N293 WeakPolarHBondContact CA-OD1 3.45Å; R124-N293 VanDerWaalsContact CG-OD1 3.28Å; R124-N293 WeakPolarHBondContact CG-OD1 3.42Å; R124-M467 HydrophobicContact CB-CE 4.21Å; R124-F470 PolarHBondContact NH2-O 3.31Å; R124-N472 PolarHBondContact NH1-OD1 3.18Å
125	L	94.1	Very high	93.1	Very high	0 Å²	0	18.5 Å²	18.5	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-61.8	-49	175.8	-173	68.2	0	0	0	111	L121 A122 A123 T129 L133 V136 I457 F460 T461 V466 M467	L121-L125 PolarHBondContact O-N 2.97Å; A122-L125 PolarHBondContact O-N 3.03Å; A123-L125 VanDerWaalsContact C-N 3.35Å; A123-L125 PolarHBondContact O-N 3.16Å; L125-T129 HydrophobicContact CD1-CG2 3.81Å; L125-T129 HydrophobicContact CG-CG2 4.48Å; L125-T129 WeakPolarHBondContact O-CB 3.46Å; L125-T129 WeakPolarHBondContact O-CG2 3.36Å; L125-T129 PolarHBondContact O-N 3.26Å; L125-T129 PolarHBondContact O-OG1 3.11Å; L125-L133 HydrophobicContact CD2-CB 4.15Å; L125-L133 HydrophobicContact CD2-CD1 3.58Å; L125-L133 HydrophobicContact CD2-CG 4.47Å; L125-V136 HydrophobicContact CD2-CG2 4.39Å; L125-V136 HydrophobicContact CG-CG2 4.49Å; L125-I457 HydrophobicContact CD2-CG1 4.42Å; L125-F460 HydrophobicContact CD1-CB 4.01Å; L125-F460 HydrophobicContact CD2-CB 4.49Å; L125-T461 HydrophobicContact CB-CG2 3.93Å; L125-T461 HydrophobicContact CD1-CG2 4.16Å; L125-V466 HydrophobicContact CD1-CG1 4.05Å; L125-M467 HydrophobicContact CD1-SD 3.79Å
126	G	92.5	Very high	93.1	Very high	2 Å²	2	18.7 Å²	18.7	2%	0.021	9%	0.092	C	C	.	.	H	α-helix	trans	-63.8	-41.8	179.6	0	0	0	0	0	113.8	A122 A123 G130 L131 S273	A122-G126 PolarHBondContact O-N 3.41Å; A123-G126 PolarHBondContact O-N 3.08Å; G126-G130 WeakPolarHBondContact O-CA 3.45Å; G126-G130 PolarHBondContact O-N 3.27Å; G126-L131 WeakPolarHBondContact CA-O 3.18Å; G126-S273 WeakPolarHBondContact CA-O 3.5Å
127	V	92.7	Very high	92.9	Very high	8 Å²	8	17.7 Å²	17.7	5%	0.048	9%	0.087	C	C	.	.	H	α-helix	trans	-69.9	-45.1	179.4	174.5	0	0	0	0	112.1	A123 V276 V289 A292 F296	A123-V127 WeakPolarHBondContact O-CB 3.36Å; A123-V127 VanDerWaalsContact O-CG2 3.26Å; A123-V127 WeakPolarHBondContact O-CG2 3.36Å; A123-V127 PolarHBondContact O-N 3.37Å; V127-V276 HydrophobicContact CG2-CB 3.91Å; V127-V276 HydrophobicContact CG2-CG1 4.36Å; V127-V276 HydrophobicContact CG2-CG2 4.04Å; V127-V289 HydrophobicContact CG1-CG1 4.36Å; V127-A292 HydrophobicContact CG1-CB 3.96Å; V127-F296 HydrophobicContact CG2-CD2 3.54Å; V127-F296 HydrophobicContact CG2-CE2 3.56Å
128	V	92.8	Very high	92.8	Very high	22 Å²	22	16.5 Å²	16.5	13%	0.133	8%	0.08	C	C	.	.	H	α-helix	trans	-75.2	-50.6	-175.8	173.8	0	0	0	0	111.5	R124 V289 M467 F470	R124-V128 VanDerWaalsContact O-CB 3.28Å; R124-V128 WeakPolarHBondContact O-CB 3.45Å; R124-V128 WeakPolarHBondContact O-CG2 3.39Å; R124-V128 PolarHBondContact O-N 3.45Å; V128-V289 HydrophobicContact CG2-CG1 3.9Å; V128-M467 HydrophobicContact CB-CE 4.4Å; V128-M467 HydrophobicContact CB-SD 4.31Å; V128-M467 HydrophobicContact CG1-SD 4.33Å; V128-M467 HydrophobicContact CG2-CE 4.29Å; V128-F470 HydrophobicContact CG1-CB 4.18Å; V128-F470 HydrophobicContact CG1-CD2 4.01Å; V128-F470 HydrophobicContact CG1-CG 4.44Å; V128-F470 HydrophobicContact CG2-CB 3.8Å; V128-F470 HydrophobicContact CG2-CD2 4.03Å; V128-F470 HydrophobicContact CG2-CG 3.9Å
129	T	89.8	Confident	92.7	Very high	30 Å²	30	23.1 Å²	23.1	18%	0.184	10%	0.104	C	C	.	.	H	α-helix	trans	-80.2	-24.3	-176.2	68.7	0	0	0	0	112.7	L125 L131 V466 M467	L125-T129 HydrophobicContact CD1-CG2 3.81Å; L125-T129 HydrophobicContact CG-CG2 4.48Å; L125-T129 WeakPolarHBondContact O-CB 3.46Å; L125-T129 WeakPolarHBondContact O-CG2 3.36Å; L125-T129 PolarHBondContact O-N 3.26Å; L125-T129 PolarHBondContact O-OG1 3.11Å; T129-L131 PolarHBondContact O-N 2.65Å; T129-L131 PolarHBondContact OG1-N 2.9Å; T129-L131 PolarHBondContact OG1-O 3.09Å; T129-V466 HydrophobicContact CG2-CG1 3.59Å; T129-M467 HydrophobicContact CG2-SD 4.4Å
130	G	88.7	Confident	92.3	Very high	4 Å²	4	24.3 Å²	24.3	4%	0.041	11%	0.109	C	C	.	.	S	Bend	trans	74.7	4	-168.1	0	0	0	0	0	115.1	G126 K277 R283	G126-G130 WeakPolarHBondContact O-CA 3.45Å; G126-G130 PolarHBondContact O-N 3.27Å; G130-K277 VanDerWaalsContact O-CE 3.26Å; G130-K277 WeakPolarHBondContact O-CE 3.07Å; G130-R283 VanDerWaalsContact CA-NH2 3.33Å
131	L	90.4	Very high	92	Very high	25 Å²	25	20.8 Å²	20.8	13%	0.131	10%	0.096	C	C	.	.	S	Bend	trans	-119.6	140.7	-177.2	-58.8	174.6	0	0	0	109.5	G126 T129 E135 V136	G126-L131 WeakPolarHBondContact CA-O 3.18Å; T129-L131 PolarHBondContact O-N 2.65Å; T129-L131 PolarHBondContact OG1-N 2.9Å; T129-L131 PolarHBondContact OG1-O 3.09Å; L131-E135 WeakPolarHBondContact CA-OE2 3.22Å; L131-E135 HydrophobicContact CB-CB 3.99Å; L131-E135 HydrophobicContact CD2-CB 4.24Å; L131-V136 HydrophobicContact CB-CG2 3.8Å; L131-V136 HydrophobicContact CD1-CG2 4.4Å
132	H	92.7	Very high	91.8	Very high	6 Å²	6	22.9 Å²	22.9	3%	0.028	11%	0.11	C	C	.	.			trans	-78.8	161.4	171	51.5	78.7	0	0	0	111.3	A134 E135 V136 S273 A274 K277 F396	H132-A134 PolarHBondContact O-N 3.35Å; H132-E135 IonicContact CD2-OE2 3.19Å; H132-E135 PolarHBondContact CD2-OE2 3.09Å; H132-E135 IonicContact CE1-OE2 3.8Å; H132-E135 IonicContact CG-OE2 3.31Å; H132-E135 VanDerWaalsContact CG-OE2 3.31Å; H132-E135 PolarHBondContact N-OE2 3.28Å; H132-E135 IonicContact ND1-OE2 3.71Å; H132-E135 IonicContact NE2-OE1 3.95Å; H132-E135 IonicContact NE2-OE2 3.5Å; H132-E135 WeakPolarHBondContact O-CB 3.41Å; H132-E135 PolarHBondContact O-N 2.98Å; H132-V136 PolarHBondContact O-N 3.06Å; H132-V136 VanDerWaalsContact O-N 3.15Å; H132-S273 WeakPolarHBondContact CB-OG 3.07Å; H132-A274 HydrophobicContact CB-CB 3.7Å; H132-K277 HydrophobicContact CB-CD 4.33Å; H132-K277 PolarHBondContact CD2-NZ 3.06Å; H132-K277 VanDerWaalsContact CD2-NZ 3.28Å; H132-F396 PolarHBondContact CE1-O 2.94Å; H132-F396 AromaticContact NE2-CD1 3.79Å
133	L	93.5	Very high	91.5	Very high	0 Å²	0	30.3 Å²	30.3	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-51	-40	-172.5	-178	60.3	0	0	0	112.8	L125 V136 C137 Y270 S273 P456 I457 F460	L125-L133 HydrophobicContact CD2-CB 4.15Å; L125-L133 HydrophobicContact CD2-CD1 3.58Å; L125-L133 HydrophobicContact CD2-CG 4.47Å; L133-V136 PolarHBondContact O-N 3.01Å; L133-C137 WeakPolarHBondContact O-CB 3.05Å; L133-C137 PolarHBondContact O-N 3.4Å; L133-C137 PolarHBondContact O-SG 2.96Å; L133-Y270 HydrophobicContact CB-CD1 3.72Å; L133-Y270 HydrophobicContact CB-CE1 3.97Å; L133-Y270 HydrophobicContact CB-CG 4.47Å; L133-Y270 HydrophobicContact CD2-CD1 3.8Å; L133-Y270 HydrophobicContact CD2-CD2 4.33Å; L133-Y270 HydrophobicContact CD2-CE1 3.54Å; L133-Y270 HydrophobicContact CD2-CE2 4.11Å; L133-Y270 HydrophobicContact CD2-CG 4.18Å; L133-Y270 HydrophobicContact CG-CD1 3.79Å; L133-Y270 HydrophobicContact CG-CE1 3.51Å; L133-S273 PolarHBondContact N-OG 3.06Å; L133-P456 HydrophobicContact CD1-CB 4.3Å; L133-I457 HydrophobicContact CD1-CB 4.03Å; L133-I457 HydrophobicContact CD1-CG1 4.12Å; L133-I457 HydrophobicContact CD2-CB 3.99Å; L133-I457 HydrophobicContact CD2-CD1 3.97Å; L133-I457 HydrophobicContact CD2-CG1 4.21Å; L133-F460 HydrophobicContact CD1-CD2 3.97Å
134	A	93.5	Very high	91.4	Very high	0 Å²	0	35 Å²	35	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-66.7	-36.2	177	0	0	0	0	0	114.3	H132 H138 Y270 F396 G400 F401	H132-A134 PolarHBondContact O-N 3.35Å; A134-H138 WeakPolarHBondContact O-CB 3.36Å; A134-H138 PolarHBondContact O-N 3.43Å; A134-Y270 HydrophobicContact CB-CD1 3.97Å; A134-Y270 HydrophobicContact CB-CE1 4.38Å; A134-F396 WeakPolarHBondContact CB-O 3.48Å; A134-G400 CarbonylContact O-C 3.58Å; A134-F401 HydrophobicContact CB-CD2 3.49Å; A134-F401 VanDerWaalsContact CB-CD2 3.49Å; A134-F401 HydrophobicContact CB-CE2 3.61Å; A134-F401 HydrophobicContact CB-CG 4.3Å; A134-F401 HydrophobicContact CB-CZ 4.48Å
135	E	92.9	Very high	91.2	Very high	49 Å²	49	34 Å²	34	23%	0.229	17%	0.169	C	C	.	.	H	α-helix	trans	-67.4	-37.7	173.2	-75.7	163.4	134.7	0	0	111	L131 H132 H138 R139 K277	L131-E135 WeakPolarHBondContact CA-OE2 3.22Å; L131-E135 HydrophobicContact CB-CB 3.99Å; L131-E135 HydrophobicContact CD2-CB 4.24Å; H132-E135 IonicContact CD2-OE2 3.19Å; H132-E135 PolarHBondContact CD2-OE2 3.09Å; H132-E135 IonicContact CE1-OE2 3.8Å; H132-E135 IonicContact CG-OE2 3.31Å; H132-E135 VanDerWaalsContact CG-OE2 3.31Å; H132-E135 PolarHBondContact N-OE2 3.28Å; H132-E135 IonicContact ND1-OE2 3.71Å; H132-E135 IonicContact NE2-OE1 3.95Å; H132-E135 IonicContact NE2-OE2 3.5Å; H132-E135 WeakPolarHBondContact O-CB 3.41Å; H132-E135 PolarHBondContact O-N 2.98Å; E135-H138 PolarHBondContact O-N 3.12Å; E135-R139 WeakPolarHBondContact O-CG 3.42Å; E135-R139 PolarHBondContact O-N 3.46Å; E135-K277 IonicContact OE1-NZ 2.89Å; E135-K277 PolarHBondContact OE1-NZ 3.49Å; E135-K277 IonicContact OE2-NZ 2.67Å; E135-K277 PolarHBondContact OE2-NZ 3.26Å
136	V	92.3	Very high	91.2	Very high	4 Å²	4	35.8 Å²	35.8	2%	0.024	18%	0.176	C	C	.	.	H	α-helix	trans	-68.2	-46.4	176.3	-175.9	0	0	0	0	110.5	L125 L131 H132 L133 H138 R139 Q140 F460 V466	L125-V136 HydrophobicContact CD2-CG2 4.39Å; L125-V136 HydrophobicContact CG-CG2 4.49Å; L131-V136 HydrophobicContact CB-CG2 3.8Å; L131-V136 HydrophobicContact CD1-CG2 4.4Å; H132-V136 PolarHBondContact O-N 3.06Å; H132-V136 VanDerWaalsContact O-N 3.15Å; L133-V136 PolarHBondContact O-N 3.01Å; V136-H138 PolarHBondContact O-N 3.37Å; V136-R139 PolarHBondContact O-N 3.4Å; V136-Q140 HydrophobicContact CG1-CG 4.17Å; V136-Q140 WeakPolarHBondContact O-CB 3.23Å; V136-Q140 WeakPolarHBondContact O-CG 3.42Å; V136-Q140 PolarHBondContact O-N 3.19Å; V136-F460 HydrophobicContact CB-CD2 4.31Å; V136-F460 HydrophobicContact CG1-CB 4.02Å; V136-F460 HydrophobicContact CG1-CD1 3.8Å; V136-F460 HydrophobicContact CG1-CD2 3.65Å; V136-F460 HydrophobicContact CG1-CE1 4.23Å; V136-F460 HydrophobicContact CG1-CE2 4.05Å; V136-F460 HydrophobicContact CG1-CG 3.53Å; V136-F460 HydrophobicContact CG1-CZ 4.34Å; V136-V466 HydrophobicContact CG1-CG1 4.3Å
137	C	91.8	Very high	91.2	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-52.7	-40.3	170.6	-73.4	0	0	0	0	112	L133 Y141 F401	L133-C137 WeakPolarHBondContact O-CB 3.05Å; L133-C137 PolarHBondContact O-N 3.4Å; L133-C137 PolarHBondContact O-SG 2.96Å; C137-Y141 HydrophobicContact CB-CD2 4.02Å; C137-Y141 HydrophobicContact CB-CE2 4.43Å; C137-Y141 WeakPolarHBondContact O-CB 3.4Å; C137-Y141 PolarHBondContact O-N 3.13Å; C137-F401 HydrophobicContact CB-CD1 4.11Å; C137-F401 HydrophobicContact CB-CE1 3.46Å; C137-F401 VanDerWaalsContact CB-CE1 3.46Å; C137-F401 HydrophobicContact CB-CZ 3.84Å
138	H	91.6	Very high	91.3	Very high	48 Å²	48	42.5 Å²	42.5	22%	0.222	21%	0.209	C	C	.	.	H	α-helix	trans	-65.5	-39.5	-179.1	-174.7	117.1	0	0	0	113.9	A134 E135 V136 R146 G400 F401	A134-H138 WeakPolarHBondContact O-CB 3.36Å; A134-H138 PolarHBondContact O-N 3.43Å; E135-H138 PolarHBondContact O-N 3.12Å; V136-H138 PolarHBondContact O-N 3.37Å; H138-R146 PolarHBondContact CD2-NH1 2.89Å; H138-R146 VanDerWaalsContact CE1-CZ 3.47Å; H138-R146 PolarHBondContact CE1-NH1 3.17Å; H138-R146 VanDerWaalsContact CE1-NH1 3.27Å; H138-R146 PolarHBondContact CE1-NH2 2.94Å; H138-R146 PolarHBondContact NE2-NH1 3.45Å; H138-R146 PolarHBondContact O-NH1 3.12Å; H138-G400 WeakPolarHBondContact CB-O 3.06Å; H138-G400 PolarHBondContact ND1-O 3.01Å; H138-F401 PolarHBondContact ND1-O 2.77Å
139	R	90.3	Very high	91.3	Very high	150 Å²	150	41.4 Å²	41.4	57%	0.566	20%	0.203	S	C	*	.	H	α-helix	trans	-77	-32.7	-179.4	-66.6	177.6	-174.1	-143.8	1.7	112.5	E135 V136	E135-R139 WeakPolarHBondContact O-CG 3.42Å; E135-R139 PolarHBondContact O-N 3.46Å; V136-R139 PolarHBondContact O-N 3.4Å
140	Q	87.7	Confident	91.5	Very high	26 Å²	26	42.4 Å²	42.4	12%	0.121	20%	0.204	C	C	.	.	H	α-helix	trans	-100.1	-31.6	-169.6	-64.2	-69	-22.2	0	0	114.2	V136 F460 Y555	V136-Q140 HydrophobicContact CG1-CG 4.17Å; V136-Q140 WeakPolarHBondContact O-CB 3.23Å; V136-Q140 WeakPolarHBondContact O-CG 3.42Å; V136-Q140 PolarHBondContact O-N 3.19Å; Q140-F460 HydrophobicContact CB-CD1 4.44Å; Q140-F460 HydrophobicContact CB-CE1 3.41Å; Q140-F460 VanDerWaalsContact CB-CE1 3.41Å; Q140-F460 HydrophobicContact CB-CZ 3.65Å; Q140-F460 HydrophobicContact CG-CD1 4.2Å; Q140-F460 HydrophobicContact CG-CE1 3.63Å; Q140-F460 HydrophobicContact CG-CZ 4.2Å; Q140-Y555 PolarHBondContact NE2-OH 2.99Å
141	Y	88	Confident	91.7	Very high	7 Å²	7	46.5 Å²	46.5	3%	0.027	22%	0.224	C	C	.	.	S	Bend	trans	-94.2	137.5	178.3	-67.7	-54.7	0	0	0	112.8	C137 L149 P456 F460 L525	C137-Y141 HydrophobicContact CB-CD2 4.02Å; C137-Y141 HydrophobicContact CB-CE2 4.43Å; C137-Y141 WeakPolarHBondContact O-CB 3.4Å; C137-Y141 PolarHBondContact O-N 3.13Å; Y141-L149 HydrophobicContact CD2-CD2 3.85Å; Y141-L149 HydrophobicContact CE2-CD2 3.7Å; Y141-P456 HydrophobicContact CE2-CB 4.06Å; Y141-P456 HydrophobicContact CE2-CG 4.09Å; Y141-F460 HydrophobicContact CD2-CZ 4.15Å; Y141-F460 HydrophobicContact CE1-CZ 4.46Å; Y141-F460 AromaticContact CE2-CE2 3.87Å; Y141-F460 HydrophobicContact CE2-CE2 3.87Å; Y141-F460 AromaticContact CE2-CZ 3.64Å; Y141-F460 HydrophobicContact CE2-CZ 3.64Å; Y141-F460 AromaticContact CZ-CZ 3.81Å; Y141-L525 HydrophobicContact CE1-CD2 3.98Å; Y141-L525 HydrophobicContact CE2-CD2 4.43Å
142	P	89.1	Confident	91.9	Very high	53 Å²	53	46.8 Å²	46.8	34%	0.344	23%	0.225	S	C	.	.			trans	-66.4	157.8	175.2	27.5	-32.9	0	0	0	111.8	V144 P145 R146	P142-V144 VanDerWaalsContact C-N 3.31Å; P142-V144 PolarHBondContact O-N 3.39Å; P142-P145 HydrophobicContact CG-CG 4.07Å; P142-P145 WeakPolarHBondContact O-CD 3.44Å; P142-R146 WeakPolarHBondContact O-CB 3.46Å; P142-R146 PolarHBondContact O-N 2.74Å
143	K	89.4	Confident	91.9	Very high	157 Å²	157	46.7 Å²	46.7	68%	0.683	23%	0.225	S	C	*	.	H	α-helix	trans	-47	-43.8	-166.7	-66.7	-179	179.7	178.8	0	114.9	I147	K143-I147 WeakPolarHBondContact O-CD1 3.22Å; K143-I147 VanDerWaalsContact O-CG1 3.25Å; K143-I147 WeakPolarHBondContact O-CG1 3.19Å; K143-I147 PolarHBondContact O-N 3.35Å; K143-I147 VanDerWaalsContact O-N 3.08Å
144	V	91.5	Very high	91.8	Very high	102 Å²	102	47.4 Å²	47.4	62%	0.618	23%	0.228	S	C	*	.	H	α-helix	trans	-71.7	-59.8	-175.4	173	0	0	0	0	112	P142 R146 I147 I148	P142-V144 VanDerWaalsContact C-N 3.31Å; P142-V144 PolarHBondContact O-N 3.39Å; V144-R146 PolarHBondContact O-N 3.26Å; V144-R146 VanDerWaalsContact O-N 3.16Å; V144-I147 PolarHBondContact O-N 2.94Å; V144-I147 VanDerWaalsContact O-N 3.07Å; V144-I148 HydrophobicContact CG1-CD1 3.93Å; V144-I148 WeakPolarHBondContact O-CG1 3.41Å; V144-I148 PolarHBondContact O-N 3.12Å; V144-I148 VanDerWaalsContact O-N 3.08Å
145	P	90.6	Very high	91.7	Very high	20 Å²	20	50.9 Å²	50.9	13%	0.13	25%	0.246	C	C	.	.	H	α-helix	trans	-49.9	-38.2	170.1	-33.1	37.9	0	0	0	114.2	P142 I148 L149 F521 Y524	P142-P145 HydrophobicContact CG-CG 4.07Å; P142-P145 WeakPolarHBondContact O-CD 3.44Å; P145-I148 PolarHBondContact O-N 3.11Å; P145-L149 WeakPolarHBondContact O-CB 3.36Å; P145-L149 PolarHBondContact O-N 2.74Å; P145-F521 HydrophobicContact CB-CE2 4.04Å; P145-F521 WeakPolarHBondContact O-CZ 3.27Å; P145-Y524 HydrophobicContact CB-CE1 3.84Å; P145-Y524 HydrophobicContact CG-CE1 3.76Å
146	R	92.6	Very high	91.6	Very high	39 Å²	39	48.6 Å²	48.6	15%	0.147	24%	0.235	C	C	.	.	H	α-helix	trans	-62.4	-42.3	177.5	-176	-178	71.4	-179.2	22.7	113.3	H138 P142 V144 W150 F401	H138-R146 PolarHBondContact CD2-NH1 2.89Å; H138-R146 VanDerWaalsContact CE1-CZ 3.47Å; H138-R146 PolarHBondContact CE1-NH1 3.17Å; H138-R146 VanDerWaalsContact CE1-NH1 3.27Å; H138-R146 PolarHBondContact CE1-NH2 2.94Å; H138-R146 PolarHBondContact NE2-NH1 3.45Å; H138-R146 PolarHBondContact O-NH1 3.12Å; P142-R146 WeakPolarHBondContact O-CB 3.46Å; P142-R146 PolarHBondContact O-N 2.74Å; V144-R146 PolarHBondContact O-N 3.26Å; V144-R146 VanDerWaalsContact O-N 3.16Å; R146-W150 WeakPolarHBondContact O-CB 3.49Å; R146-W150 PolarHBondContact O-N 3.27Å; R146-F401 HydrophobicContact CG-CD1 3.91Å; R146-F401 PolarHBondContact NE-O 3.36Å
147	I	93.7	Very high	91.5	Very high	84 Å²	84	48.4 Å²	48.4	43%	0.431	24%	0.235	S	C	.	.	H	α-helix	trans	-74	-37.7	-179.9	-69.7	164.5	0	0	0	111	K143 V144 W150 L151	K143-I147 WeakPolarHBondContact O-CD1 3.22Å; K143-I147 VanDerWaalsContact O-CG1 3.25Å; K143-I147 WeakPolarHBondContact O-CG1 3.19Å; K143-I147 PolarHBondContact O-N 3.35Å; K143-I147 VanDerWaalsContact O-N 3.08Å; V144-I147 PolarHBondContact O-N 2.94Å; V144-I147 VanDerWaalsContact O-N 3.07Å; I147-W150 PolarHBondContact O-N 2.92Å; I147-L151 PolarHBondContact O-N 2.92Å
148	I	94	Very high	91.5	Very high	66 Å²	66	49.8 Å²	49.8	34%	0.338	24%	0.241	S	C	.	.	H	α-helix	trans	-64.4	-44.1	173.8	-58.9	167.6	0	0	0	110	V144 P145 W150 L151 M152 F521	V144-I148 HydrophobicContact CG1-CD1 3.93Å; V144-I148 WeakPolarHBondContact O-CG1 3.41Å; V144-I148 PolarHBondContact O-N 3.12Å; V144-I148 VanDerWaalsContact O-N 3.08Å; P145-I148 PolarHBondContact O-N 3.11Å; I148-W150 PolarHBondContact O-N 3.28Å; I148-L151 PolarHBondContact O-N 3.23Å; I148-M152 WeakPolarHBondContact O-CG 3.25Å; I148-M152 PolarHBondContact O-N 3.23Å; I148-F521 HydrophobicContact CB-CE1 4.08Å; I148-F521 HydrophobicContact CB-CE2 4.28Å; I148-F521 HydrophobicContact CB-CZ 3.91Å; I148-F521 HydrophobicContact CG2-CD1 3.62Å; I148-F521 HydrophobicContact CG2-CD2 4.35Å; I148-F521 HydrophobicContact CG2-CE1 3.49Å; I148-F521 VanDerWaalsContact CG2-CE1 3.49Å; I148-F521 HydrophobicContact CG2-CE2 4.24Å; I148-F521 HydrophobicContact CG2-CG 4.08Å; I148-F521 HydrophobicContact CG2-CZ 3.82Å
149	L	93.3	Very high	91.4	Very high	0 Å²	0	47.5 Å²	47.5	0%	0	23%	0.231	C	C	.	.	H	α-helix	trans	-63.3	-40.3	177	-174.9	54.2	0	0	0	112.2	Y141 P145 V153 F401 F452 P456 F521 L525	Y141-L149 HydrophobicContact CD2-CD2 3.85Å; Y141-L149 HydrophobicContact CE2-CD2 3.7Å; P145-L149 WeakPolarHBondContact O-CB 3.36Å; P145-L149 PolarHBondContact O-N 2.74Å; L149-V153 HydrophobicContact CD1-CG2 4.46Å; L149-V153 WeakPolarHBondContact O-CG2 3.31Å; L149-V153 PolarHBondContact O-N 3.04Å; L149-V153 VanDerWaalsContact O-N 3.16Å; L149-F401 HydrophobicContact CB-CE1 4Å; L149-F401 HydrophobicContact CD2-CE1 3.77Å; L149-F401 HydrophobicContact CD2-CZ 4.02Å; L149-F401 HydrophobicContact CG-CE1 3.63Å; L149-F401 HydrophobicContact CG-CZ 3.75Å; L149-F452 HydrophobicContact CD1-CB 3.61Å; L149-F452 HydrophobicContact CD1-CD1 4.06Å; L149-F452 HydrophobicContact CD1-CG 4.15Å; L149-P456 HydrophobicContact CD2-CG 3.97Å; L149-F521 HydrophobicContact CB-CE1 4.39Å; L149-F521 HydrophobicContact CB-CZ 4.06Å; L149-L525 HydrophobicContact CD1-CD1 4.28Å
150	W	94.2	Very high	91.3	Very high	51 Å²	51	40.4 Å²	40.4	19%	0.193	20%	0.204	C	C	.	.	H	α-helix	trans	-58.1	-52.1	171.8	169.7	60.7	0	0	0	111.8	R146 I147 I148 M152 V153 E154 M398 F401 L402	R146-W150 WeakPolarHBondContact O-CB 3.49Å; R146-W150 PolarHBondContact O-N 3.27Å; I147-W150 PolarHBondContact O-N 2.92Å; I148-W150 PolarHBondContact O-N 3.28Å; W150-M152 VanDerWaalsContact C-N 3.3Å; W150-M152 PolarHBondContact O-N 3.19Å; W150-V153 PolarHBondContact O-N 2.67Å; W150-V153 VanDerWaalsContact O-N 3.14Å; W150-E154 HydrophobicContact CZ2-CB 4.37Å; W150-E154 HydrophobicContact CZ2-CG 4.03Å; W150-E154 PolarHBondContact NE1-OE2 2.74Å; W150-E154 WeakPolarHBondContact O-CB 3.46Å; W150-E154 PolarHBondContact O-N 2.89Å; W150-M398 HydrophobicContact CZ2-CE 4.42Å; W150-F401 HydrophobicContact CB-CB 3.71Å; W150-F401 HydrophobicContact CB-CD1 4Å; W150-F401 HydrophobicContact CB-CD2 4.35Å; W150-F401 HydrophobicContact CB-CG 3.8Å; W150-F401 HydrophobicContact CG-CB 3.93Å; W150-F401 HydrophobicContact CG-CG 4.36Å; W150-L402 HydrophobicContact CD2-CD1 3.86Å; W150-L402 HydrophobicContact CD2-CD2 4Å; W150-L402 HydrophobicContact CD2-CG 4.07Å; W150-L402 HydrophobicContact CE3-CD1 4.19Å; W150-L402 HydrophobicContact CE3-CD2 4.1Å; W150-L402 HydrophobicContact CG-CD1 4.47Å; W150-L402 HydrophobicContact CG-CD2 4.18Å; W150-L402 HydrophobicContact CG-CG 4.22Å; W150-L402 HydrophobicContact CH2-CD1 4.14Å; W150-L402 HydrophobicContact CZ2-CD1 3.81Å; W150-L402 HydrophobicContact CZ3-CD1 4.31Å
151	L	93.5	Very high	91.4	Very high	89 Å²	89	39.1 Å²	39.1	47%	0.466	20%	0.199	S	C	.	.	H	α-helix	trans	-58.4	-41.6	-178.5	-175	117.3	0	0	0	112	I147 I148 E154 L155	I147-L151 PolarHBondContact O-N 2.92Å; I148-L151 PolarHBondContact O-N 3.23Å; L151-E154 PolarHBondContact O-N 3.05Å; L151-L155 HydrophobicContact CD2-CD1 3.9Å; L151-L155 HydrophobicContact CG-CD1 4.29Å; L151-L155 WeakPolarHBondContact O-CB 3.16Å; L151-L155 VanDerWaalsContact O-CG 3.24Å; L151-L155 WeakPolarHBondContact O-CG 3.36Å; L151-L155 PolarHBondContact O-N 3.4Å
152	M	93.1	Very high	91.5	Very high	32 Å²	32	39.8 Å²	39.8	16%	0.158	20%	0.202	C	C	.	.	H	α-helix	trans	-61.7	-44.5	175.8	-72.6	-60.6	-174.9	0	0	112.6	I148 W150 L155 A156 Q449 F452 Y518	I148-M152 WeakPolarHBondContact O-CG 3.25Å; I148-M152 PolarHBondContact O-N 3.23Å; W150-M152 VanDerWaalsContact C-N 3.3Å; W150-M152 PolarHBondContact O-N 3.19Å; M152-L155 PolarHBondContact O-N 3.15Å; M152-A156 PolarHBondContact O-N 2.91Å; M152-Q449 VanDerWaalsContact CB-OE1 3.32Å; M152-Q449 PolarHBondContact O-OE1 3.06Å; M152-Q449 VanDerWaalsContact O-OE1 3.08Å; M152-F452 HydrophobicContact CB-CB 4.49Å; M152-F452 HydrophobicContact CB-CD2 3.61Å; M152-F452 HydrophobicContact CB-CE2 3.93Å; M152-F452 HydrophobicContact CB-CG 4Å; M152-F452 HydrophobicContact CE-CE2 4.22Å; M152-F452 HydrophobicContact CE-CZ 4.16Å; M152-F452 HydrophobicContact CG-CD2 3.85Å; M152-F452 HydrophobicContact CG-CE1 4.47Å; M152-F452 HydrophobicContact CG-CE2 3.62Å; M152-F452 HydrophobicContact CG-CG 4.34Å; M152-F452 HydrophobicContact CG-CZ 3.98Å; M152-F452 HydrophobicContact SD-CD2 4.34Å; M152-F452 HydrophobicContact SD-CE2 3.7Å; M152-F452 HydrophobicContact SD-CZ 4.22Å; M152-Y518 HydrophobicContact CE-CD2 4.49Å
153	V	92.6	Very high	91.5	Very high	3 Å²	3	37.3 Å²	37.3	2%	0.018	19%	0.186	C	C	.	.	H	α-helix	trans	-71.6	-36	178.6	-179.2	0	0	0	0	111.8	L149 W150 L155 A156 I157 Y270 V397	L149-V153 HydrophobicContact CD1-CG2 4.46Å; L149-V153 WeakPolarHBondContact O-CG2 3.31Å; L149-V153 PolarHBondContact O-N 3.04Å; L149-V153 VanDerWaalsContact O-N 3.16Å; W150-V153 PolarHBondContact O-N 2.67Å; W150-V153 VanDerWaalsContact O-N 3.14Å; V153-L155 VanDerWaalsContact C-N 3.35Å; V153-A156 WeakPolarHBondContact O-CB 3.38Å; V153-A156 PolarHBondContact O-N 3.06Å; V153-I157 HydrophobicContact CG1-CD1 4.14Å; V153-I157 WeakPolarHBondContact O-CD1 3.44Å; V153-I157 WeakPolarHBondContact O-CG1 3.44Å; V153-I157 PolarHBondContact O-N 3.16Å; V153-Y270 HydrophobicContact CB-CE2 4.38Å; V153-Y270 HydrophobicContact CG1-CD2 3.81Å; V153-Y270 HydrophobicContact CG1-CE2 3.72Å; V153-Y270 HydrophobicContact CG1-CG 4.43Å; V153-Y270 HydrophobicContact CG2-CE2 3.62Å; V153-V397 HydrophobicContact CB-CG1 4.2Å; V153-V397 HydrophobicContact CG1-CB 4.39Å; V153-V397 HydrophobicContact CG1-CG1 3.88Å; V153-V397 HydrophobicContact CG1-CG2 3.6Å
154	E	91.8	Very high	91.6	Very high	16 Å²	16	29.9 Å²	29.9	8%	0.075	15%	0.154	C	C	.	.	H	α-helix	trans	-65.2	-38.6	174.2	-155.4	76.7	-143	0	0	111	W150 L151 I157 I158 M398	W150-E154 HydrophobicContact CZ2-CB 4.37Å; W150-E154 HydrophobicContact CZ2-CG 4.03Å; W150-E154 PolarHBondContact NE1-OE2 2.74Å; W150-E154 WeakPolarHBondContact O-CB 3.46Å; W150-E154 PolarHBondContact O-N 2.89Å; L151-E154 PolarHBondContact O-N 3.05Å; E154-I157 PolarHBondContact O-N 3.31Å; E154-I158 HydrophobicContact CG-CD1 4.38Å; E154-I158 WeakPolarHBondContact O-CD1 3.33Å; E154-I158 VanDerWaalsContact O-CG1 3.32Å; E154-I158 WeakPolarHBondContact O-CG1 3.49Å; E154-I158 PolarHBondContact O-N 3.03Å; E154-M398 WeakPolarHBondContact OE2-CG 3.38Å
155	L	91.1	Very high	91.5	Very high	73 Å²	73	25 Å²	25	38%	0.382	12%	0.124	S	C	.	.	H	α-helix	trans	-63.2	-37.8	171.4	-74.5	168.3	0	0	0	112.6	L151 M152 V153 I157 G159	L151-L155 HydrophobicContact CD2-CD1 3.9Å; L151-L155 HydrophobicContact CG-CD1 4.29Å; L151-L155 WeakPolarHBondContact O-CB 3.16Å; L151-L155 VanDerWaalsContact O-CG 3.24Å; L151-L155 WeakPolarHBondContact O-CG 3.36Å; L151-L155 PolarHBondContact O-N 3.4Å; M152-L155 PolarHBondContact O-N 3.15Å; V153-L155 VanDerWaalsContact C-N 3.35Å; L155-I157 VanDerWaalsContact C-N 3.32Å; L155-G159 PolarHBondContact O-N 3.02Å
156	A	91.3	Very high	91.5	Very high	0 Å²	0	24.2 Å²	24.2	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-64.3	-36.8	173.6	0	0	0	0	0	112.3	M152 V153 G159 S160 Q446 Q449	M152-A156 PolarHBondContact O-N 2.91Å; V153-A156 WeakPolarHBondContact O-CB 3.38Å; V153-A156 PolarHBondContact O-N 3.06Å; A156-G159 PolarHBondContact O-N 3.07Å; A156-S160 PolarHBondContact O-N 3.09Å; A156-S160 VanDerWaalsContact O-N 3.13Å; A156-Q446 PolarHBondContact O-NE2 2.86Å; A156-Q446 PolarHBondContact O-OE1 3.24Å; A156-Q449 HydrophobicContact CB-CB 3.8Å; A156-Q449 HydrophobicContact CB-CG 3.87Å
157	I	90.9	Very high	91.4	Very high	1 Å²	1	22.4 Å²	22.4	1%	0.005	11%	0.112	C	C	.	.	H	α-helix	trans	-70.3	-48.4	177	-68.4	159.7	0	0	0	110.6	V153 E154 L155 G159 S160 D161 H267 V397	V153-I157 HydrophobicContact CG1-CD1 4.14Å; V153-I157 WeakPolarHBondContact O-CD1 3.44Å; V153-I157 WeakPolarHBondContact O-CG1 3.44Å; V153-I157 PolarHBondContact O-N 3.16Å; E154-I157 PolarHBondContact O-N 3.31Å; L155-I157 VanDerWaalsContact C-N 3.32Å; I157-G159 PolarHBondContact O-N 2.93Å; I157-S160 WeakPolarHBondContact O-CB 3.29Å; I157-S160 PolarHBondContact O-N 3Å; I157-S160 VanDerWaalsContact O-N 3.12Å; I157-D161 WeakPolarHBondContact O-CB 3.32Å; I157-D161 PolarHBondContact O-N 3.41Å; I157-H267 HydrophobicContact CD1-CB 4.22Å; I157-H267 HydrophobicContact CG1-CB 3.49Å; I157-H267 VanDerWaalsContact CG1-CB 3.49Å; I157-V397 HydrophobicContact CD1-CB 4.05Å; I157-V397 HydrophobicContact CD1-CG1 4.25Å; I157-V397 HydrophobicContact CD1-CG2 3.9Å
158	I	90.3	Very high	91.3	Very high	28 Å²	28	18.4 Å²	18.4	14%	0.144	9%	0.091	C	C	.	.	H	α-helix	trans	-58.4	-36.2	174	-67.6	159.1	0	0	0	110.9	E154 D161 M162 I418	E154-I158 HydrophobicContact CG-CD1 4.38Å; E154-I158 WeakPolarHBondContact O-CD1 3.33Å; E154-I158 VanDerWaalsContact O-CG1 3.32Å; E154-I158 WeakPolarHBondContact O-CG1 3.49Å; E154-I158 PolarHBondContact O-N 3.03Å; I158-D161 WeakPolarHBondContact O-CB 3.24Å; I158-D161 PolarHBondContact O-N 2.69Å; I158-M162 WeakPolarHBondContact O-CG 3.28Å; I158-M162 PolarHBondContact O-N 3.08Å; I158-I418 HydrophobicContact CD1-CG2 3.86Å; I158-I418 HydrophobicContact CG1-CG2 4.22Å; I158-I418 HydrophobicContact CG2-CG2 3.95Å
159	G	89.6	Confident	91.2	Very high	1 Å²	1	15.3 Å²	15.3	1%	0.01	8%	0.076	C	C	.	.	H	α-helix	trans	-59.7	-50.1	173.5	0	0	0	0	0	112.4	L155 A156 I157 D161 M162 Q163	L155-G159 PolarHBondContact O-N 3.02Å; A156-G159 PolarHBondContact O-N 3.07Å; I157-G159 PolarHBondContact O-N 2.93Å; G159-D161 VanDerWaalsContact C-N 3.34Å; G159-D161 PolarHBondContact O-N 2.94Å; G159-M162 PolarHBondContact O-N 3.42Å; G159-Q163 WeakPolarHBondContact O-CG 3.36Å; G159-Q163 PolarHBondContact O-N 3.11Å
160	S	89.3	Confident	91.1	Very high	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-60.5	-43.3	176.2	-167.6	0	0	0	0	111.8	A156 I157 M162 Q163 E164 H267 Q446	A156-S160 PolarHBondContact O-N 3.09Å; A156-S160 VanDerWaalsContact O-N 3.13Å; I157-S160 WeakPolarHBondContact O-CB 3.29Å; I157-S160 PolarHBondContact O-N 3Å; I157-S160 VanDerWaalsContact O-N 3.12Å; S160-M162 VanDerWaalsContact C-N 3.27Å; S160-M162 PolarHBondContact O-N 3.38Å; S160-Q163 WeakPolarHBondContact O-CB 3.27Å; S160-Q163 PolarHBondContact O-N 3.32Å; S160-E164 VanDerWaalsContact O-CD 3.28Å; S160-E164 VanDerWaalsContact O-CG 3.29Å; S160-E164 WeakPolarHBondContact O-CG 3.36Å; S160-E164 PolarHBondContact O-N 3.12Å; S160-E164 PolarHBondContact OG-OE1 3.21Å; S160-H267 PolarHBondContact OG-CE1 3.16Å; S160-Q446 VanDerWaalsContact N-NE2 3.17Å
161	D	90.3	Very high	91	Very high	0 Å²	0	13 Å²	13	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-54.7	-41.7	177.3	-159.2	-51.9	0	0	0	111.4	I157 I158 G159 V165 R416 A419	I157-D161 WeakPolarHBondContact O-CB 3.32Å; I157-D161 PolarHBondContact O-N 3.41Å; I158-D161 WeakPolarHBondContact O-CB 3.24Å; I158-D161 PolarHBondContact O-N 2.69Å; G159-D161 VanDerWaalsContact C-N 3.34Å; G159-D161 PolarHBondContact O-N 2.94Å; D161-V165 VanDerWaalsContact O-CG2 3.3Å; D161-V165 WeakPolarHBondContact O-CG2 3.33Å; D161-V165 PolarHBondContact O-N 2.85Å; D161-V165 VanDerWaalsContact O-N 3.14Å; D161-R416 IonicContact OD1-CZ 2.77Å; D161-R416 IonicContact OD1-NE 3.72Å; D161-R416 PolarHBondContact OD1-NE 3.27Å; D161-R416 IonicContact OD1-NH1 3.12Å; D161-R416 IonicContact OD1-NH2 2.76Å; D161-R416 PolarHBondContact OD1-NH2 2.97Å; D161-R416 IonicContact OD2-CZ 3.59Å; D161-R416 IonicContact OD2-NE 3.04Å; D161-R416 PolarHBondContact OD2-NE 3.23Å; D161-R416 IonicContact OD2-NH2 2.73Å; D161-R416 PolarHBondContact OD2-NH2 2.87Å; D161-A419 HydrophobicContact CB-CB 3.63Å; D161-A419 VanDerWaalsContact CG-CB 3.42Å; D161-A419 WeakPolarHBondContact OD1-CB 3.25Å
162	M	89.4	Confident	91	Very high	21 Å²	21	9.8 Å²	9.8	10%	0.103	5%	0.05	C	C	.	.	H	α-helix	trans	-66.2	-43.2	173.7	-68.7	177.1	64	0	0	112.7	I158 G159 S160 E164 V165 I166 A419 P422 M438 L442	I158-M162 WeakPolarHBondContact O-CG 3.28Å; I158-M162 PolarHBondContact O-N 3.08Å; G159-M162 PolarHBondContact O-N 3.42Å; S160-M162 VanDerWaalsContact C-N 3.27Å; S160-M162 PolarHBondContact O-N 3.38Å; M162-E164 VanDerWaalsContact C-N 3.32Å; M162-E164 PolarHBondContact O-N 2.73Å; M162-V165 PolarHBondContact O-N 3.32Å; M162-I166 WeakPolarHBondContact O-CD1 3.12Å; M162-I166 WeakPolarHBondContact O-CG1 3.36Å; M162-I166 PolarHBondContact O-N 2.88Å; M162-A419 HydrophobicContact CG-CB 3.74Å; M162-P422 HydrophobicContact CE-CB 4.11Å; M162-P422 HydrophobicContact CE-CG 3.93Å; M162-P422 HydrophobicContact SD-CG 3.96Å; M162-M438 HydrophobicContact CE-CE 3.89Å; M162-M438 HydrophobicContact CE-CG 4.33Å; M162-M438 HydrophobicContact CE-SD 3.52Å; M162-M438 VanDerWaalsContact CE-SD 3.52Å; M162-L442 HydrophobicContact CB-CD1 3.64Å; M162-L442 HydrophobicContact CE-CD1 4.38Å; M162-L442 HydrophobicContact SD-CD2 4.41Å
163	Q	89.9	Confident	90.9	Very high	1 Å²	1	8.8 Å²	8.8	1%	0.005	5%	0.046	C	C	.	.	H	α-helix	trans	-62.6	-39.4	178.7	-56.9	-177.7	-93.4	0	0	111.6	G159 S160 I166 G167 N439 L442 N443	G159-Q163 WeakPolarHBondContact O-CG 3.36Å; G159-Q163 PolarHBondContact O-N 3.11Å; S160-Q163 WeakPolarHBondContact O-CB 3.27Å; S160-Q163 PolarHBondContact O-N 3.32Å; Q163-I166 PolarHBondContact O-N 3.49Å; Q163-G167 PolarHBondContact O-N 3.2Å; Q163-N439 WeakPolarHBondContact CB-OD1 3.29Å; Q163-N439 WeakPolarHBondContact CG-OD1 3.16Å; Q163-N439 PolarHBondContact NE2-OD1 3.17Å; Q163-L442 HydrophobicContact CG-CB 3.68Å; Q163-L442 HydrophobicContact CG-CD1 3.67Å; Q163-L442 HydrophobicContact CG-CG 4.28Å; Q163-N443 PolarHBondContact NE2-OD1 2.99Å
164	E	89.8	Confident	90.7	Very high	0 Å²	0	8.7 Å²	8.7	0%	0	5%	0.045	C	C	.	.	H	α-helix	trans	-60.8	-44.8	174.2	-71.2	153.3	-160.4	0	0	112.8	S160 M162 S168 S386 T387 R416	S160-E164 VanDerWaalsContact O-CD 3.28Å; S160-E164 VanDerWaalsContact O-CG 3.29Å; S160-E164 WeakPolarHBondContact O-CG 3.36Å; S160-E164 PolarHBondContact O-N 3.12Å; S160-E164 PolarHBondContact OG-OE1 3.21Å; M162-E164 VanDerWaalsContact C-N 3.32Å; M162-E164 PolarHBondContact O-N 2.73Å; E164-S168 VanDerWaalsContact O-CB 3.26Å; E164-S168 WeakPolarHBondContact O-CB 3.16Å; E164-S168 PolarHBondContact O-N 3.29Å; E164-S168 PolarHBondContact O-OG 3.44Å; E164-S386 PolarHBondContact OE1-OG 3.37Å; E164-T387 WeakPolarHBondContact OE2-CA 3.29Å; E164-T387 PolarHBondContact OE2-N 3.16Å; E164-R416 IonicContact OE2-CZ 3.75Å; E164-R416 IonicContact OE2-NH1 2.81Å; E164-R416 IonicContact OE2-NH2 2.88Å; E164-R416 PolarHBondContact OE2-NH2 3.45Å
165	V	90.7	Very high	90.8	Very high	0 Å²	0	10.9 Å²	10.9	0%	0	6%	0.057	C	C	.	.	H	α-helix	trans	-70.2	-41.7	179.2	171.1	0	0	0	0	111.2	D161 M162 A169 V186 I420 T423	D161-V165 VanDerWaalsContact O-CG2 3.3Å; D161-V165 WeakPolarHBondContact O-CG2 3.33Å; D161-V165 PolarHBondContact O-N 2.85Å; D161-V165 VanDerWaalsContact O-N 3.14Å; M162-V165 PolarHBondContact O-N 3.32Å; V165-A169 VanDerWaalsContact O-CB 3.24Å; V165-A169 WeakPolarHBondContact O-CB 3.03Å; V165-A169 PolarHBondContact O-N 2.82Å; V165-V186 HydrophobicContact CG1-CB 4.31Å; V165-V186 HydrophobicContact CG1-CG1 3.88Å; V165-V186 HydrophobicContact CG1-CG2 4.05Å; V165-I420 HydrophobicContact CG1-CG1 4.25Å; V165-I420 HydrophobicContact CG2-CD1 4.49Å; V165-I420 HydrophobicContact CG2-CG1 3.9Å; V165-T423 HydrophobicContact CG1-CG2 3.91Å
166	I	89.6	Confident	90.7	Very high	4 Å²	4	8.2 Å²	8.2	2%	0.021	4%	0.044	C	C	.	.	H	α-helix	trans	-59	-55	174.1	-65.8	160.1	0	0	0	110.1	M162 Q163 S168 A169 I170 T423 M438 L442	M162-I166 WeakPolarHBondContact O-CD1 3.12Å; M162-I166 WeakPolarHBondContact O-CG1 3.36Å; M162-I166 PolarHBondContact O-N 2.88Å; Q163-I166 PolarHBondContact O-N 3.49Å; I166-S168 PolarHBondContact O-N 3.13Å; I166-A169 PolarHBondContact O-N 3.43Å; I166-I170 HydrophobicContact CG2-CD1 3.69Å; I166-I170 HydrophobicContact CG2-CG1 4.46Å; I166-I170 WeakPolarHBondContact O-CB 3.25Å; I166-I170 WeakPolarHBondContact O-CG1 3.47Å; I166-I170 PolarHBondContact O-N 2.72Å; I166-T423 HydrophobicContact CG1-CG2 3.77Å; I166-M438 HydrophobicContact CD1-CE 3.64Å; I166-M438 HydrophobicContact CD1-CG 4.45Å; I166-M438 HydrophobicContact CG1-CE 4.06Å; I166-L442 HydrophobicContact CD1-CD1 4.09Å
167	G	91.4	Very high	90.4	Very high	0 Å²	0	10.9 Å²	10.9	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-60	-44.3	-178.5	0	0	0	0	0	112.9	Q163 I170 A171 I379	Q163-G167 PolarHBondContact O-N 3.2Å; G167-I170 PolarHBondContact O-N 2.94Å; G167-A171 WeakPolarHBondContact O-CB 3.43Å; G167-A171 PolarHBondContact O-N 3.14Å; G167-I379 WeakPolarHBondContact O-CG2 3.16Å
168	S	92.3	Very high	89.9	Confident	0 Å²	0	12.6 Å²	12.6	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-63.8	-41.5	177	-58.2	0	0	0	0	112.2	E164 I166 A171 I172	E164-S168 VanDerWaalsContact O-CB 3.26Å; E164-S168 WeakPolarHBondContact O-CB 3.16Å; E164-S168 PolarHBondContact O-N 3.29Å; E164-S168 PolarHBondContact O-OG 3.44Å; I166-S168 PolarHBondContact O-N 3.13Å; S168-A171 PolarHBondContact O-N 3.48Å; S168-I172 WeakPolarHBondContact O-CD1 3.41Å; S168-I172 VanDerWaalsContact O-CG1 3.25Å; S168-I172 WeakPolarHBondContact O-CG1 3.42Å; S168-I172 PolarHBondContact O-N 3.44Å
169	A	91.5	Very high	89.8	Confident	2 Å²	2	21.5 Å²	21.5	2%	0.017	11%	0.11	C	C	.	.	H	α-helix	trans	-67	-39.9	177.4	0	0	0	0	0	112.6	V165 I166 I172 N173 V186	V165-A169 VanDerWaalsContact O-CB 3.24Å; V165-A169 WeakPolarHBondContact O-CB 3.03Å; V165-A169 PolarHBondContact O-N 2.82Å; I166-A169 PolarHBondContact O-N 3.43Å; A169-I172 PolarHBondContact O-N 3.27Å; A169-N173 WeakPolarHBondContact O-CB 3.44Å; A169-N173 PolarHBondContact O-N 3.21Å; A169-V186 HydrophobicContact CB-CG2 3.64Å
170	I	89.8	Confident	89.8	Confident	1 Å²	1	24.1 Å²	24.1	1%	0.005	12%	0.123	C	C	.	.	H	α-helix	trans	-61.3	-46.4	173.1	-73.7	171.9	0	0	0	110.7	I166 G167 I172 N173 L174 L182 I356 Y357 T436	I166-I170 HydrophobicContact CG2-CD1 3.69Å; I166-I170 HydrophobicContact CG2-CG1 4.46Å; I166-I170 WeakPolarHBondContact O-CB 3.25Å; I166-I170 WeakPolarHBondContact O-CG1 3.47Å; I166-I170 PolarHBondContact O-N 2.72Å; G167-I170 PolarHBondContact O-N 2.94Å; I170-I172 PolarHBondContact O-N 3.21Å; I170-N173 PolarHBondContact O-N 3.11Å; I170-L174 HydrophobicContact CG2-CD1 4.07Å; I170-L174 WeakPolarHBondContact O-CG 3.48Å; I170-L174 PolarHBondContact O-N 3.48Å; I170-L182 HydrophobicContact CG1-CD2 3.96Å; I170-I356 HydrophobicContact CD1-CB 4.48Å; I170-I356 HydrophobicContact CG2-CB 4.38Å; I170-I356 HydrophobicContact CG2-CG2 3.81Å; I170-Y357 HydrophobicContact CG2-CD2 4.14Å; I170-Y357 HydrophobicContact CG2-CG 4.45Å; I170-T436 HydrophobicContact CD1-CG2 4.12Å
171	A	93.3	Very high	89.7	Confident	0 Å²	0	26.7 Å²	26.7	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-60.8	-44.9	177.1	0	0	0	0	0	112.3	G167 S168 N173 L174 L175 A376 I379 L380	G167-A171 WeakPolarHBondContact O-CB 3.43Å; G167-A171 PolarHBondContact O-N 3.14Å; S168-A171 PolarHBondContact O-N 3.48Å; A171-N173 VanDerWaalsContact C-N 3.34Å; A171-N173 PolarHBondContact O-N 3.28Å; A171-L174 PolarHBondContact O-N 2.74Å; A171-L175 WeakPolarHBondContact O-CB 3.38Å; A171-L175 VanDerWaalsContact O-CG 3.22Å; A171-L175 WeakPolarHBondContact O-CG 3.45Å; A171-L175 PolarHBondContact O-N 3.13Å; A171-A376 WeakPolarHBondContact CB-O 3.44Å; A171-I379 HydrophobicContact CB-CB 4.18Å; A171-I379 HydrophobicContact CB-CG2 3.99Å; A171-L380 HydrophobicContact CB-CB 3.89Å; A171-L380 HydrophobicContact CB-CD1 4.39Å
172	I	93.3	Very high	89.6	Confident	22 Å²	22	27.6 Å²	27.6	11%	0.113	15%	0.145	C	C	.	.	H	α-helix	trans	-61.8	-41.7	176.3	-69.4	162.6	0	0	0	111.1	S168 A169 I170 S176 I180 I188 L380	S168-I172 WeakPolarHBondContact O-CD1 3.41Å; S168-I172 VanDerWaalsContact O-CG1 3.25Å; S168-I172 WeakPolarHBondContact O-CG1 3.42Å; S168-I172 PolarHBondContact O-N 3.44Å; A169-I172 PolarHBondContact O-N 3.27Å; I170-I172 PolarHBondContact O-N 3.21Å; I172-S176 VanDerWaalsContact O-CB 3.25Å; I172-S176 WeakPolarHBondContact O-CB 3.27Å; I172-S176 PolarHBondContact O-N 2.88Å; I172-S176 PolarHBondContact O-OG 2.86Å; I172-I180 HydrophobicContact CG2-CB 4.17Å; I172-I180 HydrophobicContact CG2-CD1 3.79Å; I172-I180 HydrophobicContact CG2-CG2 3.84Å; I172-I188 HydrophobicContact CD1-CB 4.1Å; I172-I188 HydrophobicContact CD1-CG2 3.73Å; I172-I188 HydrophobicContact CG2-CD1 4.13Å; I172-L380 HydrophobicContact CG1-CD1 4.24Å
173	N	90.6	Very high	89.6	Confident	12 Å²	12	32.4 Å²	32.4	6%	0.064	16%	0.162	C	C	.	.	H	α-helix	trans	-61.4	-49.4	176.8	178.9	-92.8	0	0	0	111.6	A169 I170 A171 S176 V177 G178 I180 L182 Y357	A169-N173 WeakPolarHBondContact O-CB 3.44Å; A169-N173 PolarHBondContact O-N 3.21Å; I170-N173 PolarHBondContact O-N 3.11Å; A171-N173 VanDerWaalsContact C-N 3.34Å; A171-N173 PolarHBondContact O-N 3.28Å; N173-S176 PolarHBondContact O-N 2.73Å; N173-S176 PolarHBondContact O-OG 3.07Å; N173-V177 PolarHBondContact O-N 3.03Å; N173-G178 PolarHBondContact O-N 2.79Å; N173-I180 PolarHBondContact ND2-O 2.98Å; N173-L182 HydrophobicContact CB-CD2 3.7Å; N173-Y357 VanDerWaalsContact OD1-CE2 3.25Å; N173-Y357 WeakPolarHBondContact OD1-CE2 3.38Å
174	L	89.8	Confident	89.6	Confident	1 Å²	1	32.8 Å²	32.8	1%	0.005	17%	0.166	C	C	.	.	H	α-helix	trans	-59.8	-49.4	176.4	-72.5	170.8	0	0	0	112.3	I170 A171 S176 V177 Y357 V361 L372 A376	I170-L174 HydrophobicContact CG2-CD1 4.07Å; I170-L174 WeakPolarHBondContact O-CG 3.48Å; I170-L174 PolarHBondContact O-N 3.48Å; A171-L174 PolarHBondContact O-N 2.74Å; L174-S176 PolarHBondContact O-N 2.77Å; L174-V177 PolarHBondContact O-N 3.4Å; L174-Y357 HydrophobicContact CD1-CD2 4.29Å; L174-Y357 HydrophobicContact CD2-CD2 3.66Å; L174-Y357 HydrophobicContact CD2-CE2 3.56Å; L174-Y357 HydrophobicContact CG-CD2 3.82Å; L174-Y357 HydrophobicContact CG-CE2 4.02Å; L174-V361 HydrophobicContact CD2-CG2 4.07Å; L174-L372 HydrophobicContact CB-CD2 4.14Å; L174-L372 HydrophobicContact CD2-CD1 4.46Å; L174-L372 HydrophobicContact CD2-CD2 4.18Å; L174-L372 HydrophobicContact CD2-CG 4.32Å; L174-A376 HydrophobicContact CB-CB 3.81Å; L174-A376 HydrophobicContact CD1-CB 4.24Å
175	L	92.3	Very high	89.6	Confident	62 Å²	62	32.8 Å²	32.8	33%	0.325	17%	0.166	S	C	.	.	H	α-helix	trans	-60	-32.6	177.1	-70.5	169.3	0	0	0	112.5	A171 V177 Y373 A376 V377 L380	A171-L175 WeakPolarHBondContact O-CB 3.38Å; A171-L175 VanDerWaalsContact O-CG 3.22Å; A171-L175 WeakPolarHBondContact O-CG 3.45Å; A171-L175 PolarHBondContact O-N 3.13Å; L175-V177 VanDerWaalsContact C-N 3.29Å; L175-V177 PolarHBondContact O-N 3.02Å; L175-Y373 HydrophobicContact CD2-CD1 4.3Å; L175-A376 HydrophobicContact CD2-CB 3.94Å; L175-A376 HydrophobicContact CG-CB 3.81Å; L175-V377 HydrophobicContact CD2-CG2 4Å; L175-L380 HydrophobicContact CD1-CD2 3.9Å
176	S	89.8	Confident	89.6	Confident	16 Å²	16	32.9 Å²	32.9	11%	0.112	17%	0.167	C	C	.	.	T	Hydrogen-bonded Turn	trans	-79.7	-6.8	177.8	79.9	0	0	0	0	114.4	I172 N173 L174 G178 R179 I180	I172-S176 VanDerWaalsContact O-CB 3.25Å; I172-S176 WeakPolarHBondContact O-CB 3.27Å; I172-S176 PolarHBondContact O-N 2.88Å; I172-S176 PolarHBondContact O-OG 2.86Å; N173-S176 PolarHBondContact O-N 2.73Å; N173-S176 PolarHBondContact O-OG 3.07Å; L174-S176 PolarHBondContact O-N 2.77Å; S176-G178 VanDerWaalsContact C-N 3.32Å; S176-G178 PolarHBondContact OG-N 3.27Å; S176-R179 WeakPolarHBondContact O-CB 3.35Å; S176-R179 WeakPolarHBondContact O-CG 3.48Å; S176-R179 PolarHBondContact O-N 3.35Å; S176-R179 PolarHBondContact OG-N 3.4Å; S176-R179 VanDerWaalsContact OG-N 3.16Å; S176-I180 PolarHBondContact OG-N 2.96Å
177	V	84.3	Confident	89.6	Confident	56 Å²	56	36.3 Å²	36.3	34%	0.339	18%	0.184	S	C	.	.	T	Hydrogen-bonded Turn	trans	55.6	46.8	-168.1	-159.9	0	0	0	0	111.2	N173 L174 L175 R179 P340 Y373	N173-V177 PolarHBondContact O-N 3.03Å; L174-V177 PolarHBondContact O-N 3.4Å; L175-V177 VanDerWaalsContact C-N 3.29Å; L175-V177 PolarHBondContact O-N 3.02Å; V177-R179 PolarHBondContact O-N 2.97Å; V177-P340 HydrophobicContact CG1-CG 4.27Å; V177-Y373 HydrophobicContact CG2-CE1 4.12Å; V177-Y373 WeakPolarHBondContact CG2-OH 3.4Å
178	G	81.4	Confident	89.6	Confident	37 Å²	37	40 Å²	40	38%	0.381	20%	0.203	S	C	.	.	T	Hydrogen-bonded Turn	trans	72.6	0.3	-179.6	0	0	0	0	0	116	N173 S176 I180	N173-G178 PolarHBondContact O-N 2.79Å; S176-G178 VanDerWaalsContact C-N 3.32Å; S176-G178 PolarHBondContact OG-N 3.27Å; G178-I180 VanDerWaalsContact C-N 3.3Å; G178-I180 PolarHBondContact O-N 3.25Å
179	R	86.9	Confident	89.5	Confident	215 Å²	215	40.1 Å²	40.1	81%	0.811	20%	0.204	S	C	*	.	S	Bend	trans	-66.4	-30.3	178.1	-69	-172.3	-175.4	112.8	-5.4	113.5	S176 V177	S176-R179 WeakPolarHBondContact O-CB 3.35Å; S176-R179 WeakPolarHBondContact O-CG 3.48Å; S176-R179 PolarHBondContact O-N 3.35Å; S176-R179 PolarHBondContact OG-N 3.4Å; S176-R179 VanDerWaalsContact OG-N 3.16Å; V177-R179 PolarHBondContact O-N 2.97Å
180	I	89.9	Confident	89.2	Confident	57 Å²	57	43.3 Å²	43.3	29%	0.292	22%	0.22	S	C	.	.	S	Bend	trans	-100.2	111.2	173.3	-60.5	173.3	0	0	0	106.9	I172 N173 S176 G178 I188	I172-I180 HydrophobicContact CG2-CB 4.17Å; I172-I180 HydrophobicContact CG2-CD1 3.79Å; I172-I180 HydrophobicContact CG2-CG2 3.84Å; N173-I180 PolarHBondContact ND2-O 2.98Å; S176-I180 PolarHBondContact OG-N 2.96Å; G178-I180 VanDerWaalsContact C-N 3.3Å; G178-I180 PolarHBondContact O-N 3.25Å; I180-I188 HydrophobicContact CD1-CD1 4.08Å; I180-I188 HydrophobicContact CG2-CD1 3.92Å
181	P	88.6	Confident	89	Confident	53 Å²	53	45.9 Å²	45.9	34%	0.344	24%	0.242	S	C	.	.			trans	-66.9	160.4	177.1	29.8	-35.6	0	0	0	110.9	W183 G184 G185	P181-W183 VanDerWaalsContact C-N 3.35Å; P181-W183 HydrophobicContact CG-CD2 4.1Å; P181-W183 VanDerWaalsContact CG-CE2 3.45Å; P181-W183 HydrophobicContact CG-CG 4.41Å; P181-W183 HydrophobicContact CG-CZ2 3.7Å; P181-W183 PolarHBondContact O-N 3.33Å; P181-G184 CarbonylContact O-C 3.56Å; P181-G184 VanDerWaalsContact O-CA 3.28Å; P181-G184 WeakPolarHBondContact O-CA 3.08Å; P181-G184 PolarHBondContact O-N 3.44Å; P181-G185 PolarHBondContact O-N 3.46Å
182	L	86.6	Confident	88.5	Confident	19 Å²	19	46.3 Å²	46.3	10%	0.099	24%	0.244	C	C	.	.	H	α-helix	trans	-57.9	-42.2	-174.4	-67.9	170.9	0	0	0	112.9	I170 N173 G184 G185 V186 V432 L435	I170-L182 HydrophobicContact CG1-CD2 3.96Å; N173-L182 HydrophobicContact CB-CD2 3.7Å; L182-G184 PolarHBondContact O-N 2.78Å; L182-G185 WeakPolarHBondContact O-CA 3.49Å; L182-G185 PolarHBondContact O-N 3.38Å; L182-V186 WeakPolarHBondContact O-CG2 3.21Å; L182-V186 PolarHBondContact O-N 2.8Å; L182-V432 HydrophobicContact CD1-CB 4.21Å; L182-V432 HydrophobicContact CD1-CG1 3.87Å; L182-V432 HydrophobicContact CD1-CG2 3.79Å; L182-L435 HydrophobicContact CB-CD1 4.12Å; L182-L435 HydrophobicContact CD1-CD1 3.67Å; L182-L435 HydrophobicContact CG-CD1 4.48Å
183	W	89.3	Confident	87.7	Confident	123 Å²	123	45.6 Å²	45.6	47%	0.466	24%	0.24	S	C	.	.	H	α-helix	trans	-59.6	-31.9	172.6	65.9	-102.3	0	0	0	113	P181 V186 L187 L424 A427 V428	P181-W183 VanDerWaalsContact C-N 3.35Å; P181-W183 HydrophobicContact CG-CD2 4.1Å; P181-W183 VanDerWaalsContact CG-CE2 3.45Å; P181-W183 HydrophobicContact CG-CG 4.41Å; P181-W183 HydrophobicContact CG-CZ2 3.7Å; P181-W183 PolarHBondContact O-N 3.33Å; W183-V186 PolarHBondContact O-N 3.23Å; W183-L187 HydrophobicContact CE3-CD1 3.85Å; W183-L187 HydrophobicContact CZ3-CD1 3.94Å; W183-L187 WeakPolarHBondContact O-CG 3.43Å; W183-L187 PolarHBondContact O-N 3.4Å; W183-L424 HydrophobicContact CB-CD1 3.85Å; W183-A427 HydrophobicContact CB-CB 4.09Å; W183-V428 HydrophobicContact CB-CG2 3.65Å; W183-V428 HydrophobicContact CG-CG2 4.07Å
184	G	89.9	Confident	87.2	Confident	9 Å²	9	50.2 Å²	50.2	9%	0.093	26%	0.26	C	S	.	.	H	α-helix	trans	-69.6	-39.4	173.3	0	0	0	0	0	111.9	P181 L182 L187 I188	P181-G184 CarbonylContact O-C 3.56Å; P181-G184 VanDerWaalsContact O-CA 3.28Å; P181-G184 WeakPolarHBondContact O-CA 3.08Å; P181-G184 PolarHBondContact O-N 3.44Å; L182-G184 PolarHBondContact O-N 2.78Å; G184-L187 PolarHBondContact O-N 2.88Å; G184-I188 WeakPolarHBondContact O-CD1 3.45Å; G184-I188 VanDerWaalsContact O-CG1 3.27Å; G184-I188 WeakPolarHBondContact O-CG1 3.41Å; G184-I188 PolarHBondContact O-N 3Å
185	G	90.5	Very high	86.7	Confident	0 Å²	0	53.7 Å²	53.7	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-59.9	-44.8	169.9	0	0	0	0	0	112.5	P181 L182 L187 I188 T189	P181-G185 PolarHBondContact O-N 3.46Å; L182-G185 WeakPolarHBondContact O-CA 3.49Å; L182-G185 PolarHBondContact O-N 3.38Å; G185-L187 VanDerWaalsContact C-N 3.27Å; G185-L187 PolarHBondContact O-N 2.81Å; G185-I188 PolarHBondContact O-N 3.49Å; G185-T189 PolarHBondContact O-N 3.29Å; G185-T189 VanDerWaalsContact O-N 3.07Å
186	V	90.1	Very high	86	Confident	2 Å²	2	51 Å²	51	1%	0.012	27%	0.267	C	S	.	.	H	α-helix	trans	-64.2	-27.4	176	173.8	0	0	0	0	112.8	V165 A169 L182 W183 T189 I420 T423 L424 A427	V165-V186 HydrophobicContact CG1-CB 4.31Å; V165-V186 HydrophobicContact CG1-CG1 3.88Å; V165-V186 HydrophobicContact CG1-CG2 4.05Å; A169-V186 HydrophobicContact CB-CG2 3.64Å; L182-V186 WeakPolarHBondContact O-CG2 3.21Å; L182-V186 PolarHBondContact O-N 2.8Å; W183-V186 PolarHBondContact O-N 3.23Å; V186-T189 PolarHBondContact O-OG1 2.97Å; V186-I420 HydrophobicContact CG1-CG2 3.91Å; V186-T423 HydrophobicContact CG1-CG2 4.45Å; V186-T423 HydrophobicContact CG2-CG2 4.04Å; V186-L424 HydrophobicContact CB-CD1 4.4Å; V186-L424 HydrophobicContact CG1-CB 3.89Å; V186-L424 HydrophobicContact CG1-CD1 4.11Å; V186-A427 HydrophobicContact CG2-CB 4.4Å
187	L	90.8	Very high	85.3	Confident	75 Å²	75	52 Å²	52	39%	0.393	27%	0.271	S	S	.	.	H	α-helix	trans	-80.7	-28.6	170.3	-69.5	177	0	0	0	112.8	W183 G184 G185 I190 L424	W183-L187 HydrophobicContact CE3-CD1 3.85Å; W183-L187 HydrophobicContact CZ3-CD1 3.94Å; W183-L187 WeakPolarHBondContact O-CG 3.43Å; W183-L187 PolarHBondContact O-N 3.4Å; G184-L187 PolarHBondContact O-N 2.88Å; G185-L187 VanDerWaalsContact C-N 3.27Å; G185-L187 PolarHBondContact O-N 2.81Å; L187-I190 HydrophobicContact CD2-CD1 3.84Å; L187-I190 WeakPolarHBondContact O-CB 3.4Å; L187-I190 PolarHBondContact O-N 2.79Å; L187-L424 HydrophobicContact CD2-CD1 4.3Å; L187-L424 HydrophobicContact CD2-CD2 3.96Å; L187-L424 HydrophobicContact CG-CD1 4.2Å
188	I	90.9	Very high	85.1	Confident	77 Å²	77	55.2 Å²	55.2	40%	0.395	28%	0.281	S	S	.	.	H	α-helix	trans	-72.4	-30	176.7	-70.6	161.5	0	0	0	111.6	I172 I180 G184 G185 I190 A191	I172-I188 HydrophobicContact CD1-CB 4.1Å; I172-I188 HydrophobicContact CD1-CG2 3.73Å; I172-I188 HydrophobicContact CG2-CD1 4.13Å; I180-I188 HydrophobicContact CD1-CD1 4.08Å; I180-I188 HydrophobicContact CG2-CD1 3.92Å; G184-I188 WeakPolarHBondContact O-CD1 3.45Å; G184-I188 VanDerWaalsContact O-CG1 3.27Å; G184-I188 WeakPolarHBondContact O-CG1 3.41Å; G184-I188 PolarHBondContact O-N 3Å; G185-I188 PolarHBondContact O-N 3.49Å; I188-I190 PolarHBondContact O-N 2.93Å; I188-A191 WeakPolarHBondContact O-CB 3.45Å; I188-A191 PolarHBondContact O-N 3.42Å
189	T	89.5	Confident	84.8	Confident	3 Å²	3	55.3 Å²	55.3	2%	0.018	27%	0.272	C	S	.	.	H	α-helix	trans	-61.5	-25.5	172.9	57.6	0	0	0	0	112.5	G185 V186 A191 D192	G185-T189 PolarHBondContact O-N 3.29Å; G185-T189 VanDerWaalsContact O-N 3.07Å; V186-T189 PolarHBondContact O-OG1 2.97Å; T189-A191 PolarHBondContact O-N 2.72Å; T189-D192 WeakPolarHBondContact O-CB 3.41Å; T189-D192 PolarHBondContact O-N 2.9Å
190	I	86.3	Confident	84	Confident	69 Å²	69	46.1 Å²	46.1	35%	0.354	24%	0.239	S	C	.	.	H	α-helix	trans	-56.2	-26.1	171.3	-54.9	171.9	0	0	0	111.4	L187 I188 F194 I420	L187-I190 HydrophobicContact CD2-CD1 3.84Å; L187-I190 WeakPolarHBondContact O-CB 3.4Å; L187-I190 PolarHBondContact O-N 2.79Å; I188-I190 PolarHBondContact O-N 2.93Å; I190-F194 HydrophobicContact CG2-CE2 4.23Å; I190-F194 WeakPolarHBondContact O-CD2 3.41Å; I190-I420 HydrophobicContact CD1-CG2 4.49Å; I190-I420 HydrophobicContact CG1-CD1 3.78Å; I190-I420 HydrophobicContact CG1-CG2 4.49Å
191	A	85.4	Confident	83.4	Confident	55 Å²	55	52.2 Å²	52.2	46%	0.455	26%	0.264	S	S	.	.	H	α-helix	trans	-72.7	-32.3	172.9	0	0	0	0	0	113.8	I188 T189 T193 F194 V195	I188-A191 WeakPolarHBondContact O-CB 3.45Å; I188-A191 PolarHBondContact O-N 3.42Å; T189-A191 PolarHBondContact O-N 2.72Å; A191-T193 PolarHBondContact O-N 3.07Å; A191-F194 PolarHBondContact O-N 3.41Å; A191-F194 VanDerWaalsContact O-N 3.16Å; A191-V195 PolarHBondContact O-N 2.89Å; A191-V195 VanDerWaalsContact O-N 3.11Å
192	D	81.9	Confident	82.7	Confident	9 Å²	9	55 Å²	55	5%	0.048	27%	0.268	C	S	.	.	H	α-helix	trans	-60.5	-32.6	177.3	72.6	29.7	0	0	0	112.2	T189 F194 V195 F196 Q384 T387	T189-D192 WeakPolarHBondContact O-CB 3.41Å; T189-D192 PolarHBondContact O-N 2.9Å; D192-F194 VanDerWaalsContact C-N 3.31Å; D192-F194 PolarHBondContact O-N 2.93Å; D192-V195 CarbonylContact O-C 3.59Å; D192-V195 WeakPolarHBondContact O-CA 3.5Å; D192-V195 WeakPolarHBondContact O-CB 3.47Å; D192-V195 PolarHBondContact O-N 3.13Å; D192-F196 PolarHBondContact O-N 2.92Å; D192-Q384 PolarHBondContact OD2-NE2 3.12Å; D192-T387 WeakPolarHBondContact OD1-CG2 3.49Å
193	T	77.3	Confident	82.2	Confident	7 Å²	7	55.6 Å²	55.6	4%	0.043	28%	0.279	C	S	.	.	H	α-helix	trans	-66.9	-37.3	-178.8	-63.2	0	0	0	0	110.5	A191 L197 V412 R416	A191-T193 PolarHBondContact O-N 3.07Å; T193-L197 HydrophobicContact CG2-CD1 4.38Å; T193-L197 VanDerWaalsContact O-CD1 3.32Å; T193-L197 WeakPolarHBondContact O-CD1 3.44Å; T193-L197 VanDerWaalsContact O-CG 3.24Å; T193-L197 WeakPolarHBondContact O-CG 3.5Å; T193-L197 PolarHBondContact O-N 3.3Å; T193-L197 VanDerWaalsContact O-N 3.14Å; T193-V412 HydrophobicContact CG2-CG1 3.42Å; T193-V412 VanDerWaalsContact CG2-CG1 3.42Å; T193-R416 HydrophobicContact CG2-CG 4.14Å
194	F	80.2	Confident	81.7	Confident	110 Å²	110	50.9 Å²	50.9	48%	0.482	26%	0.263	S	S	.	.	H	α-helix	trans	-72.2	-34	170.8	-65.8	-75.9	0	0	0	112.7	I190 A191 D192 L197 F198 F409	I190-F194 HydrophobicContact CG2-CE2 4.23Å; I190-F194 WeakPolarHBondContact O-CD2 3.41Å; A191-F194 PolarHBondContact O-N 3.41Å; A191-F194 VanDerWaalsContact O-N 3.16Å; D192-F194 VanDerWaalsContact C-N 3.31Å; D192-F194 PolarHBondContact O-N 2.93Å; F194-L197 PolarHBondContact O-N 2.69Å; F194-F198 WeakPolarHBondContact O-CB 3.21Å; F194-F198 PolarHBondContact O-N 3.33Å; F194-F409 HydrophobicContact CD1-CE2 4.47Å; F194-F409 AromaticContact CE1-CE2 3.99Å; F194-F409 HydrophobicContact CE1-CE2 3.99Å; F194-F409 HydrophobicContact CE1-CZ 4.2Å
195	V	79.7	Confident	81.4	Confident	74 Å²	74	54.8 Å²	54.8	45%	0.448	28%	0.275	S	S	.	.	H	α-helix	trans	-64.3	-43.8	174.3	174.6	0	0	0	0	110.9	A191 D192 F198 L199	A191-V195 PolarHBondContact O-N 2.89Å; A191-V195 VanDerWaalsContact O-N 3.11Å; D192-V195 CarbonylContact O-C 3.59Å; D192-V195 WeakPolarHBondContact O-CA 3.5Å; D192-V195 WeakPolarHBondContact O-CB 3.47Å; D192-V195 PolarHBondContact O-N 3.13Å; V195-F198 WeakPolarHBondContact O-CB 3.42Å; V195-F198 PolarHBondContact O-N 3.22Å; V195-L199 HydrophobicContact CG1-CD1 3.89Å; V195-L199 HydrophobicContact CG1-CG 4.4Å; V195-L199 VanDerWaalsContact O-CG 3.31Å; V195-L199 WeakPolarHBondContact O-CG 3.35Å; V195-L199 PolarHBondContact O-N 3.2Å
196	F	76.4	Confident	81.2	Confident	5 Å²	5	61 Å²	61	2%	0.022	30%	0.302	C	S	.	.	H	α-helix	trans	-60.1	-49.6	174.1	170.6	-120.8	0	0	0	112.2	Y50 D192 F198 L199 D200 M388 T391 Y392 V412	Y50-F196 WeakPolarHBondContact OH-CZ 3.25Å; D192-F196 PolarHBondContact O-N 2.92Å; F196-F198 PolarHBondContact O-N 2.95Å; F196-L199 PolarHBondContact O-N 3.2Å; F196-D200 PolarHBondContact O-N 2.91Å; F196-M388 HydrophobicContact CB-CG 4.13Å; F196-M388 HydrophobicContact CD2-CB 3.89Å; F196-M388 HydrophobicContact CD2-CG 3.45Å; F196-M388 VanDerWaalsContact CD2-CG 3.45Å; F196-M388 HydrophobicContact CD2-SD 3.85Å; F196-M388 HydrophobicContact CE2-CB 4.01Å; F196-M388 HydrophobicContact CE2-CG 4.09Å; F196-M388 HydrophobicContact CG-CG 3.96Å; F196-T391 VanDerWaalsContact CE1-OG1 3.25Å; F196-T391 WeakPolarHBondContact CE1-OG1 3.36Å; F196-Y392 HydrophobicContact CE2-CD2 4.48Å; F196-Y392 AromaticContact CE2-CE2 3.75Å; F196-Y392 HydrophobicContact CE2-CE2 3.75Å; F196-Y392 AromaticContact CE2-CZ 3.75Å; F196-Y392 HydrophobicContact CZ-CE1 4.26Å; F196-Y392 HydrophobicContact CZ-CE2 4.09Å; F196-Y392 AromaticContact CZ-CZ 3.92Å; F196-V412 HydrophobicContact CE1-CG2 4.32Å
197	L	75.3	Confident	80.8	Confident	36 Å²	36	61.3 Å²	61.3	19%	0.188	30%	0.303	C	S	.	.	H	α-helix	trans	-60.8	-28.1	177.3	-72.6	163.2	0	0	0	113	T193 F194 F409	T193-L197 HydrophobicContact CG2-CD1 4.38Å; T193-L197 VanDerWaalsContact O-CD1 3.32Å; T193-L197 WeakPolarHBondContact O-CD1 3.44Å; T193-L197 VanDerWaalsContact O-CG 3.24Å; T193-L197 WeakPolarHBondContact O-CG 3.5Å; T193-L197 PolarHBondContact O-N 3.3Å; T193-L197 VanDerWaalsContact O-N 3.14Å; F194-L197 PolarHBondContact O-N 2.69Å; L197-F409 HydrophobicContact CD1-CD2 3.66Å; L197-F409 HydrophobicContact CD1-CE2 4.03Å
198	F	79.9	Confident	80.7	Confident	125 Å²	125	58.6 Å²	58.6	55%	0.548	29%	0.289	S	S	.	.	H	α-helix	trans	-74.9	-42.8	171.4	-176.9	-103.7	0	0	0	111.9	F194 V195 F196 K201 Y202	F194-F198 WeakPolarHBondContact O-CB 3.21Å; F194-F198 PolarHBondContact O-N 3.33Å; V195-F198 WeakPolarHBondContact O-CB 3.42Å; V195-F198 PolarHBondContact O-N 3.22Å; F196-F198 PolarHBondContact O-N 2.95Å; F198-K201 PolarHBondContact O-N 3.13Å; F198-Y202 AromaticContact CD1-CE2 3.89Å; F198-Y202 HydrophobicContact CD1-CE2 3.89Å; F198-Y202 HydrophobicContact CD2-CE2 4.44Å; F198-Y202 HydrophobicContact CE1-CD2 4.45Å; F198-Y202 AromaticContact CE1-CE2 3.49Å; F198-Y202 HydrophobicContact CE1-CE2 3.49Å; F198-Y202 VanDerWaalsContact CE1-CE2 3.49Å; F198-Y202 AromaticContact CE1-CZ 3.99Å; F198-Y202 HydrophobicContact CE2-CE2 4.09Å; F198-Y202 HydrophobicContact CG-CE2 4.35Å; F198-Y202 AromaticContact CZ-CE2 3.61Å; F198-Y202 HydrophobicContact CZ-CE2 3.61Å; F198-Y202 AromaticContact CZ-CZ 3.83Å; F198-Y202 WeakPolarHBondContact CZ-OH 3.29Å; F198-Y202 VanDerWaalsContact O-CD2 3.24Å; F198-Y202 WeakPolarHBondContact O-CD2 3.43Å
199	L	75.5	Confident	80.6	Confident	38 Å²	38	58 Å²	58	20%	0.199	30%	0.295	C	S	.	.	H	α-helix	trans	-67.8	-34.4	-179.5	-73.3	170	0	0	0	113.8	V195 F196 K201 Y202 F210 M388	V195-L199 HydrophobicContact CG1-CD1 3.89Å; V195-L199 HydrophobicContact CG1-CG 4.4Å; V195-L199 VanDerWaalsContact O-CG 3.31Å; V195-L199 WeakPolarHBondContact O-CG 3.35Å; V195-L199 PolarHBondContact O-N 3.2Å; F196-L199 PolarHBondContact O-N 3.2Å; L199-K201 PolarHBondContact O-N 3.47Å; L199-Y202 PolarHBondContact O-N 2.89Å; L199-F210 HydrophobicContact CD1-CD1 3.73Å; L199-F210 HydrophobicContact CD1-CE1 3.44Å; L199-F210 VanDerWaalsContact CD1-CE1 3.44Å; L199-F210 HydrophobicContact CD1-CG 4.47Å; L199-F210 HydrophobicContact CD1-CZ 3.98Å; L199-M388 HydrophobicContact CD1-SD 4.48Å
200	D	70.2	Confident	80.6	Confident	23 Å²	23	60.9 Å²	60.9	12%	0.123	31%	0.308	C	S	.	.	H	α-helix	trans	-42.4	-52.4	170.8	172	-4.4	0	0	0	111	Y50 F196 Y202 G203 R408	Y50-D200 HydrophobicContact CE1-CB 3.79Å; Y50-D200 WeakPolarHBondContact CE1-OD1 3.5Å; Y50-D200 PolarHBondContact OH-OD2 3.13Å; Y50-D200 VanDerWaalsContact OH-OD2 3.07Å; F196-D200 PolarHBondContact O-N 2.91Å; D200-Y202 PolarHBondContact O-N 2.89Å; D200-G203 PolarHBondContact O-N 3.25Å; D200-R408 IonicContact OD1-NH1 2.86Å; D200-R408 PolarHBondContact OD1-NH1 2.71Å; D200-R408 VanDerWaalsContact OD2-CD 3.25Å; D200-R408 WeakPolarHBondContact OD2-CD 3.47Å; D200-R408 IonicContact OD2-CZ 3.48Å; D200-R408 IonicContact OD2-NE 3.61Å; D200-R408 IonicContact OD2-NH1 2.77Å; D200-R408 PolarHBondContact OD2-NH1 3.36Å
201	K	76.1	Confident	80.6	Confident	185 Å²	185	57.6 Å²	57.6	80%	0.804	29%	0.291	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.6	-14.4	-175.3	-165.6	170.4	-177.9	175.3	0	114.7	F198 L199	F198-K201 PolarHBondContact O-N 3.13Å; L199-K201 PolarHBondContact O-N 3.47Å
202	Y	74.5	Confident	80.9	Confident	110 Å²	110	56.2 Å²	56.2	43%	0.431	28%	0.281	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89	-7.7	-176.9	-77	-87.5	0	0	0	115	F198 L199 D200 K206	F198-Y202 AromaticContact CD1-CE2 3.89Å; F198-Y202 HydrophobicContact CD1-CE2 3.89Å; F198-Y202 HydrophobicContact CD2-CE2 4.44Å; F198-Y202 HydrophobicContact CE1-CD2 4.45Å; F198-Y202 AromaticContact CE1-CE2 3.49Å; F198-Y202 HydrophobicContact CE1-CE2 3.49Å; F198-Y202 VanDerWaalsContact CE1-CE2 3.49Å; F198-Y202 AromaticContact CE1-CZ 3.99Å; F198-Y202 HydrophobicContact CE2-CE2 4.09Å; F198-Y202 HydrophobicContact CG-CE2 4.35Å; F198-Y202 AromaticContact CZ-CE2 3.61Å; F198-Y202 HydrophobicContact CZ-CE2 3.61Å; F198-Y202 AromaticContact CZ-CZ 3.83Å; F198-Y202 WeakPolarHBondContact CZ-OH 3.29Å; F198-Y202 VanDerWaalsContact O-CD2 3.24Å; F198-Y202 WeakPolarHBondContact O-CD2 3.43Å; L199-Y202 PolarHBondContact O-N 2.89Å; D200-Y202 PolarHBondContact O-N 2.89Å; Y202-K206 WeakPolarHBondContact O-CD 3.26Å; Y202-K206 PolarHBondContact O-NZ 3.41Å
203	G	77.3	Confident	81.5	Confident	32 Å²	32	61.4 Å²	61.4	33%	0.33	30%	0.304	S	S	.	.			trans	90.5	152.7	170	0	0	0	0	0	114.9	D200 R205 K206 L207	D200-G203 PolarHBondContact O-N 3.25Å; G203-R205 VanDerWaalsContact C-N 3.34Å; G203-R205 PolarHBondContact O-N 3.08Å; G203-R205 VanDerWaalsContact O-N 3.12Å; G203-K206 PolarHBondContact O-N 3.44Å; G203-L207 PolarHBondContact O-N 3.23Å
204	L	78.3	Confident	82.3	Confident	25 Å²	25	61.6 Å²	61.6	13%	0.131	31%	0.305	C	S	.	.	H	α-helix	trans	-53	-42	-162.4	-161.6	110	0	0	0	114.4	F51 I55 K206 L207 E208 R279	F51-L204 HydrophobicContact CD1-CD1 4.16Å; F51-L204 HydrophobicContact CE1-CD1 4.03Å; I55-L204 HydrophobicContact CD1-CD2 3.56Å; L204-K206 PolarHBondContact O-N 3.47Å; L204-L207 WeakPolarHBondContact O-CB 3.4Å; L204-L207 PolarHBondContact O-N 2.74Å; L204-E208 WeakPolarHBondContact CD2-OE1 3.4Å; L204-E208 VanDerWaalsContact O-CG 3.32Å; L204-E208 WeakPolarHBondContact O-CG 3.22Å; L204-E208 PolarHBondContact O-N 3.25Å; L204-R279 VanDerWaalsContact CD2-NH1 3.33Å
205	R	83.9	Confident	82.9	Confident	90 Å²	90	56.7 Å²	56.7	34%	0.34	28%	0.283	S	S	.	.	H	α-helix	trans	-66.9	-30.5	-179.8	-76.8	-50.8	-151.1	168.9	6	114.7	I55 W71 A72 T74 G203 E208 A209	I55-R205 HydrophobicContact CD1-CG 3.98Å; I55-R205 HydrophobicContact CG1-CG 4.45Å; W71-R205 PolarHBondContact O-NH2 2.99Å; A72-R205 PolarHBondContact O-NH2 3.49Å; T74-R205 PolarHBondContact O-NH1 3.41Å; G203-R205 VanDerWaalsContact C-N 3.34Å; G203-R205 PolarHBondContact O-N 3.08Å; G203-R205 VanDerWaalsContact O-N 3.12Å; R205-E208 WeakPolarHBondContact CD-OE2 3.28Å; R205-E208 IonicContact CZ-OE2 2.71Å; R205-E208 IonicContact NE-OE2 2.79Å; R205-E208 IonicContact NH1-OE2 3.73Å; R205-E208 PolarHBondContact NH1-OE2 3Å; R205-A209 PolarHBondContact O-N 3.3Å
206	K	85.5	Confident	83.7	Confident	132 Å²	132	56.9 Å²	56.9	57%	0.574	29%	0.285	S	S	*	.	H	α-helix	trans	-80.1	-35.5	177.9	-61.7	-176.9	-161.3	143	0	110.9	Y202 G203 L204 A209 F210	Y202-K206 WeakPolarHBondContact O-CD 3.26Å; Y202-K206 PolarHBondContact O-NZ 3.41Å; G203-K206 PolarHBondContact O-N 3.44Å; L204-K206 PolarHBondContact O-N 3.47Å; K206-A209 PolarHBondContact O-N 3.4Å; K206-F210 PolarHBondContact O-N 3.36Å
207	L	82.8	Confident	84.6	Confident	7 Å²	7	58.6 Å²	58.6	4%	0.037	29%	0.294	C	S	.	.	H	α-helix	trans	-61.4	-47.6	171.3	-173.2	107.6	0	0	0	111.3	L79 G203 L204 A209 F210 F211 Y392	L79-L207 HydrophobicContact CD2-CD2 4.26Å; G203-L207 PolarHBondContact O-N 3.23Å; L204-L207 WeakPolarHBondContact O-CB 3.4Å; L204-L207 PolarHBondContact O-N 2.74Å; L207-A209 VanDerWaalsContact C-N 3.31Å; L207-A209 PolarHBondContact O-N 3.33Å; L207-F210 PolarHBondContact O-N 2.88Å; L207-F211 HydrophobicContact CD1-CE2 4.45Å; L207-F211 HydrophobicContact CD2-CD2 4.2Å; L207-F211 HydrophobicContact CD2-CE2 3.7Å; L207-F211 HydrophobicContact CG-CD2 4.07Å; L207-F211 HydrophobicContact CG-CE2 3.76Å; L207-F211 WeakPolarHBondContact O-CD2 3.46Å; L207-F211 PolarHBondContact O-N 3.04Å; L207-Y392 VanDerWaalsContact CD1-OH 3.31Å; L207-Y392 WeakPolarHBondContact CD1-OH 3.06Å; L207-Y392 HydrophobicContact CD2-CE2 4.05Å; L207-Y392 WeakPolarHBondContact CD2-OH 3.38Å
208	E	87.6	Confident	85.6	Confident	19 Å²	19	56.9 Å²	56.9	9%	0.089	29%	0.285	C	S	.	.	H	α-helix	trans	-56.4	-41.4	172.5	-73.9	172.7	170.9	0	0	112.6	G75 L79 L204 R205 G212 R279	G75-E208 WeakPolarHBondContact CA-OE1 3.41Å; L79-E208 HydrophobicContact CD1-CB 4.45Å; L79-E208 HydrophobicContact CD1-CG 3.92Å; L204-E208 WeakPolarHBondContact CD2-OE1 3.4Å; L204-E208 VanDerWaalsContact O-CG 3.32Å; L204-E208 WeakPolarHBondContact O-CG 3.22Å; L204-E208 PolarHBondContact O-N 3.25Å; R205-E208 WeakPolarHBondContact CD-OE2 3.28Å; R205-E208 IonicContact CZ-OE2 2.71Å; R205-E208 IonicContact NE-OE2 2.79Å; R205-E208 IonicContact NH1-OE2 3.73Å; R205-E208 PolarHBondContact NH1-OE2 3Å; E208-G212 PolarHBondContact O-N 3.17Å; E208-R279 VanDerWaalsContact CD-NH2 3.33Å; E208-R279 IonicContact OE1-CZ 2.94Å; E208-R279 VanDerWaalsContact OE1-CZ 3.25Å; E208-R279 IonicContact OE1-NH1 3.1Å; E208-R279 PolarHBondContact OE1-NH1 3.18Å; E208-R279 IonicContact OE1-NH2 2.76Å; E208-R279 PolarHBondContact OE1-NH2 3Å; E208-R279 IonicContact OE2-NH2 3.15Å; E208-R279 PolarHBondContact OE2-NH2 2.83Å; E208-R279 VanDerWaalsContact OE2-NH2 3.12Å
209	A	88.6	Confident	86.3	Confident	65 Å²	65	52.5 Å²	52.5	54%	0.537	27%	0.271	S	S	.	.	H	α-helix	trans	-68.7	-36.9	176.5	0	0	0	0	0	113.1	R205 K206 L207 G212 F213	R205-A209 PolarHBondContact O-N 3.3Å; K206-A209 PolarHBondContact O-N 3.4Å; L207-A209 VanDerWaalsContact C-N 3.31Å; L207-A209 PolarHBondContact O-N 3.33Å; A209-G212 PolarHBondContact O-N 3.48Å; A209-F213 PolarHBondContact O-N 3.45Å
210	F	89.3	Confident	87.4	Confident	63 Å²	63	56.5 Å²	56.5	28%	0.276	29%	0.293	S	S	.	.	H	α-helix	trans	-65.1	-41.8	175.2	-179.4	-116.2	0	0	0	111.8	L199 K206 L207 F213 L214 M388	L199-F210 HydrophobicContact CD1-CD1 3.73Å; L199-F210 HydrophobicContact CD1-CE1 3.44Å; L199-F210 VanDerWaalsContact CD1-CE1 3.44Å; L199-F210 HydrophobicContact CD1-CG 4.47Å; L199-F210 HydrophobicContact CD1-CZ 3.98Å; K206-F210 PolarHBondContact O-N 3.36Å; L207-F210 PolarHBondContact O-N 2.88Å; F210-F213 HydrophobicContact CD2-CD1 4.36Å; F210-F213 HydrophobicContact CE2-CD1 4.41Å; F210-F213 WeakPolarHBondContact O-CB 3.34Å; F210-F213 PolarHBondContact O-N 3.37Å; F210-L214 HydrophobicContact CD1-CD1 4.31Å; F210-L214 HydrophobicContact CE1-CD1 3.83Å; F210-L214 HydrophobicContact CE1-CG 4.45Å; F210-L214 HydrophobicContact CZ-CD1 4.08Å; F210-L214 HydrophobicContact CZ-CD2 4.35Å; F210-L214 HydrophobicContact CZ-CG 4.34Å; F210-L214 PolarHBondContact O-N 2.88Å; F210-M388 HydrophobicContact CD1-CE 3.97Å; F210-M388 HydrophobicContact CD1-SD 4.34Å; F210-M388 HydrophobicContact CE1-CE 3.56Å; F210-M388 HydrophobicContact CE1-SD 4.09Å
211	F	88.1	Confident	88.6	Confident	0 Å²	0	56.1 Å²	56.1	0%	0	29%	0.291	C	S	.	.	H	α-helix	trans	-62.4	-44	172	-77.1	-57.1	0	0	0	112.8	L79 I82 L207 F213 L214 I215 M388 Y392	L79-F211 HydrophobicContact CD1-CB 4.13Å; L79-F211 HydrophobicContact CD1-CD2 3.54Å; L79-F211 HydrophobicContact CD1-CE2 4.19Å; L79-F211 HydrophobicContact CD1-CG 4.14Å; L79-F211 HydrophobicContact CD2-CD2 4.05Å; L79-F211 HydrophobicContact CD2-CE2 3.85Å; L79-F211 HydrophobicContact CG-CD2 3.54Å; L79-F211 HydrophobicContact CG-CE2 3.68Å; L79-F211 HydrophobicContact CG-CG 4.27Å; I82-F211 HydrophobicContact CD1-CB 3.79Å; I82-F211 HydrophobicContact CD1-CD1 3.17Å; I82-F211 HydrophobicContact CD1-CE1 3.77Å; I82-F211 HydrophobicContact CD1-CG 3.7Å; L207-F211 HydrophobicContact CD1-CE2 4.45Å; L207-F211 HydrophobicContact CD2-CD2 4.2Å; L207-F211 HydrophobicContact CD2-CE2 3.7Å; L207-F211 HydrophobicContact CG-CD2 4.07Å; L207-F211 HydrophobicContact CG-CE2 3.76Å; L207-F211 WeakPolarHBondContact O-CD2 3.46Å; L207-F211 PolarHBondContact O-N 3.04Å; F211-F213 PolarHBondContact O-N 3.35Å; F211-L214 PolarHBondContact O-N 3.01Å; F211-L214 VanDerWaalsContact O-N 3.16Å; F211-I215 WeakPolarHBondContact O-CG1 3.25Å; F211-I215 PolarHBondContact O-N 3.13Å; F211-M388 HydrophobicContact CD1-CE 3.96Å; F211-M388 HydrophobicContact CE1-CB 3.81Å; F211-M388 HydrophobicContact CE1-CE 3.42Å; F211-M388 VanDerWaalsContact CE1-CE 3.42Å; F211-M388 HydrophobicContact CE1-CG 4.46Å; F211-M388 HydrophobicContact CE1-SD 4.07Å; F211-M388 HydrophobicContact CZ-CB 3.53Å; F211-M388 HydrophobicContact CZ-CE 4.05Å; F211-M388 HydrophobicContact CZ-CG 4.4Å; F211-M388 HydrophobicContact CZ-SD 4.07Å; F211-Y392 HydrophobicContact CE2-CE2 4.3Å; F211-Y392 HydrophobicContact CZ-CE2 4.29Å
212	G	91.2	Very high	89.5	Confident	25 Å²	25	47.4 Å²	47.4	26%	0.258	25%	0.253	S	S	.	.	H	α-helix	trans	-58	-34.9	172.9	0	0	0	0	0	113.2	E208 A209 T216	E208-G212 PolarHBondContact O-N 3.17Å; A209-G212 PolarHBondContact O-N 3.48Å; G212-T216 WeakPolarHBondContact O-CB 3.48Å; G212-T216 PolarHBondContact O-N 3.2Å; G212-T216 PolarHBondContact O-OG1 3.17Å
213	F	93.7	Very high	90.6	Very high	118 Å²	118	42.8 Å²	42.8	52%	0.518	24%	0.239	S	C	.	.	H	α-helix	trans	-67.9	-44.4	173.5	170.2	-104.1	0	0	0	112.6	A209 F210 F211 T216 I217	A209-F213 PolarHBondContact O-N 3.45Å; F210-F213 HydrophobicContact CD2-CD1 4.36Å; F210-F213 HydrophobicContact CE2-CD1 4.41Å; F210-F213 WeakPolarHBondContact O-CB 3.34Å; F210-F213 PolarHBondContact O-N 3.37Å; F211-F213 PolarHBondContact O-N 3.35Å; F213-T216 WeakPolarHBondContact O-CB 3.39Å; F213-T216 PolarHBondContact O-N 3.32Å; F213-I217 HydrophobicContact CD1-CD1 4.17Å; F213-I217 HydrophobicContact CE1-CD1 3.62Å; F213-I217 HydrophobicContact CE2-CD1 4.27Å; F213-I217 HydrophobicContact CZ-CD1 3.69Å; F213-I217 HydrophobicContact CZ-CG1 4.39Å; F213-I217 PolarHBondContact O-N 3.27Å
214	L	93.5	Very high	91.5	Very high	12 Å²	12	46.6 Å²	46.6	6%	0.063	24%	0.244	C	C	.	.	H	α-helix	trans	-63.1	-42.6	175.6	-65.4	178.4	0	0	0	112.3	F210 F211 T216 I217 M218 A381 M388	F210-L214 HydrophobicContact CD1-CD1 4.31Å; F210-L214 HydrophobicContact CE1-CD1 3.83Å; F210-L214 HydrophobicContact CE1-CG 4.45Å; F210-L214 HydrophobicContact CZ-CD1 4.08Å; F210-L214 HydrophobicContact CZ-CD2 4.35Å; F210-L214 HydrophobicContact CZ-CG 4.34Å; F210-L214 PolarHBondContact O-N 2.88Å; F211-L214 PolarHBondContact O-N 3.01Å; F211-L214 VanDerWaalsContact O-N 3.16Å; L214-T216 VanDerWaalsContact C-N 3.29Å; L214-T216 PolarHBondContact O-N 2.99Å; L214-I217 HydrophobicContact CD2-CD1 4.45Å; L214-I217 WeakPolarHBondContact O-CB 3.35Å; L214-I217 PolarHBondContact O-N 3.01Å; L214-M218 PolarHBondContact O-N 3.1Å; L214-A381 HydrophobicContact CD2-CB 4.31Å; L214-M388 HydrophobicContact CD1-CE 3.76Å
215	I	94	Very high	92.2	Very high	7 Å²	7	45.5 Å²	45.5	4%	0.036	24%	0.238	C	C	.	.	H	α-helix	trans	-61.5	-39.1	173.6	-62	165.5	0	0	0	110.7	F78 I82 L85 F211 M218 A219 V306 I310	F78-I215 HydrophobicContact CB-CD1 4.24Å; F78-I215 HydrophobicContact CD1-CD1 4.06Å; I82-I215 HydrophobicContact CD1-CD1 4.08Å; I82-I215 HydrophobicContact CD1-CG1 4.25Å; I82-I215 HydrophobicContact CG1-CD1 3.87Å; I82-I215 HydrophobicContact CG1-CG1 3.88Å; L85-I215 HydrophobicContact CD1-CG2 4.38Å; F211-I215 WeakPolarHBondContact O-CG1 3.25Å; F211-I215 PolarHBondContact O-N 3.13Å; I215-M218 HydrophobicContact CG1-CE 4.25Å; I215-M218 PolarHBondContact O-N 2.81Å; I215-A219 WeakPolarHBondContact O-CB 3.47Å; I215-A219 PolarHBondContact O-N 3.46Å; I215-V306 HydrophobicContact CG2-CG1 4.08Å; I215-I310 HydrophobicContact CG2-CD1 4.46Å
216	T	95.5	Very high	92.8	Very high	78 Å²	78	42.5 Å²	42.5	48%	0.479	23%	0.227	S	C	.	.	H	α-helix	trans	-65.6	-37.3	176.2	-57.7	0	0	0	0	111.9	G212 F213 L214 L220	G212-T216 WeakPolarHBondContact O-CB 3.48Å; G212-T216 PolarHBondContact O-N 3.2Å; G212-T216 PolarHBondContact O-OG1 3.17Å; F213-T216 WeakPolarHBondContact O-CB 3.39Å; F213-T216 PolarHBondContact O-N 3.32Å; L214-T216 VanDerWaalsContact C-N 3.29Å; L214-T216 PolarHBondContact O-N 2.99Å; T216-L220 HydrophobicContact CG2-CD1 4Å; T216-L220 HydrophobicContact CG2-CG 4.47Å; T216-L220 WeakPolarHBondContact O-CB 3.49Å; T216-L220 VanDerWaalsContact O-CG 3.25Å; T216-L220 WeakPolarHBondContact O-CG 3.41Å; T216-L220 PolarHBondContact O-N 2.66Å; T216-L220 VanDerWaalsContact O-N 3.07Å
217	I	96.4	Very high	93.2	Very high	40 Å²	40	41 Å²	41	21%	0.205	23%	0.229	C	C	.	.	H	α-helix	trans	-59.9	-53.5	171.9	-69.6	171	0	0	0	109.9	F213 L214 A219 L220 T221 V377 A381	F213-I217 HydrophobicContact CD1-CD1 4.17Å; F213-I217 HydrophobicContact CE1-CD1 3.62Å; F213-I217 HydrophobicContact CE2-CD1 4.27Å; F213-I217 HydrophobicContact CZ-CD1 3.69Å; F213-I217 HydrophobicContact CZ-CG1 4.39Å; F213-I217 PolarHBondContact O-N 3.27Å; L214-I217 HydrophobicContact CD2-CD1 4.45Å; L214-I217 WeakPolarHBondContact O-CB 3.35Å; L214-I217 PolarHBondContact O-N 3.01Å; I217-A219 VanDerWaalsContact C-N 3.32Å; I217-A219 PolarHBondContact O-N 3.29Å; I217-L220 PolarHBondContact O-N 3.35Å; I217-T221 HydrophobicContact CG2-CG2 4.03Å; I217-T221 WeakPolarHBondContact O-CG2 3.3Å; I217-T221 PolarHBondContact O-N 3.33Å; I217-T221 PolarHBondContact O-OG1 3.09Å; I217-V377 HydrophobicContact CG2-CG1 3.86Å; I217-A381 HydrophobicContact CB-CB 4.2Å; I217-A381 HydrophobicContact CG2-CB 3.81Å
218	M	95.3	Very high	93.7	Very high	0 Å²	0	42.5 Å²	42.5	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-57.4	-43.4	-179.6	-68.8	-171.9	-77.4	0	0	112.4	L85 L214 I215 L220 T221 F222 I310 A381 A382	L85-M218 HydrophobicContact CB-CE 3.97Å; L85-M218 HydrophobicContact CB-SD 4.09Å; L85-M218 HydrophobicContact CD1-CE 3.95Å; L214-M218 PolarHBondContact O-N 3.1Å; I215-M218 HydrophobicContact CG1-CE 4.25Å; I215-M218 PolarHBondContact O-N 2.81Å; M218-L220 VanDerWaalsContact C-N 3.31Å; M218-L220 PolarHBondContact O-N 3.3Å; M218-T221 WeakPolarHBondContact CA-OG1 3.34Å; M218-T221 PolarHBondContact O-N 2.65Å; M218-T221 PolarHBondContact O-OG1 3.43Å; M218-F222 HydrophobicContact CB-CD2 3.98Å; M218-F222 HydrophobicContact CB-CE2 3.84Å; M218-F222 HydrophobicContact CG-CE2 3.98Å; M218-F222 WeakPolarHBondContact O-CB 3.41Å; M218-F222 WeakPolarHBondContact O-CD2 3.49Å; M218-F222 PolarHBondContact O-N 3.38Å; M218-F222 HydrophobicContact SD-CE2 4.46Å; M218-I310 HydrophobicContact CB-CD1 4.4Å; M218-A381 HydrophobicContact CG-CB 3.91Å; M218-A382 WeakPolarHBondContact SD-CA 3.39Å; M218-A382 HydrophobicContact SD-CB 3.64Å
219	A	96.3	Very high	93.9	Very high	33 Å²	33	42.3 Å²	42.3	27%	0.273	24%	0.238	S	C	.	.	H	α-helix	trans	-61.3	-37.3	176.1	0	0	0	0	0	113	I215 I217 G223 I310	I215-A219 WeakPolarHBondContact O-CB 3.47Å; I215-A219 PolarHBondContact O-N 3.46Å; I217-A219 VanDerWaalsContact C-N 3.32Å; I217-A219 PolarHBondContact O-N 3.29Å; A219-G223 WeakPolarHBondContact O-CA 3.43Å; A219-G223 PolarHBondContact O-N 3.02Å; A219-G223 VanDerWaalsContact O-N 3.13Å; A219-I310 HydrophobicContact CB-CD1 4.04Å; A219-I310 HydrophobicContact CB-CG1 4.24Å
220	L	96.9	Very high	94.1	Very high	123 Å²	123	46.9 Å²	46.9	64%	0.644	25%	0.246	S	C	*	.	H	α-helix	trans	-77.7	-39.7	178	-70.1	172	0	0	0	112.6	T216 I217 M218 Y224	T216-L220 HydrophobicContact CG2-CD1 4Å; T216-L220 HydrophobicContact CG2-CG 4.47Å; T216-L220 WeakPolarHBondContact O-CB 3.49Å; T216-L220 VanDerWaalsContact O-CG 3.25Å; T216-L220 WeakPolarHBondContact O-CG 3.41Å; T216-L220 PolarHBondContact O-N 2.66Å; T216-L220 VanDerWaalsContact O-N 3.07Å; I217-L220 PolarHBondContact O-N 3.35Å; M218-L220 VanDerWaalsContact C-N 3.31Å; M218-L220 PolarHBondContact O-N 3.3Å; L220-Y224 VanDerWaalsContact O-CB 3.29Å; L220-Y224 WeakPolarHBondContact O-CB 3.35Å; L220-Y224 PolarHBondContact O-N 3.31Å
221	T	96.1	Very high	94.3	Very high	14 Å²	14	44 Å²	44	9%	0.086	23%	0.234	C	C	.	.	H	α-helix	trans	-69.5	-54.2	179.8	54.1	0	0	0	0	111.3	I217 M218 G223 Y224 E225 I374 V377 G378	I217-T221 HydrophobicContact CG2-CG2 4.03Å; I217-T221 WeakPolarHBondContact O-CG2 3.3Å; I217-T221 PolarHBondContact O-N 3.33Å; I217-T221 PolarHBondContact O-OG1 3.09Å; M218-T221 WeakPolarHBondContact CA-OG1 3.34Å; M218-T221 PolarHBondContact O-N 2.65Å; M218-T221 PolarHBondContact O-OG1 3.43Å; T221-G223 VanDerWaalsContact C-N 3.31Å; T221-G223 PolarHBondContact O-N 3Å; T221-Y224 WeakPolarHBondContact O-CB 3.36Å; T221-Y224 PolarHBondContact O-N 3.11Å; T221-Y224 VanDerWaalsContact O-N 3.17Å; T221-E225 PolarHBondContact O-N 2.87Å; T221-E225 VanDerWaalsContact O-N 3.12Å; T221-I374 WeakPolarHBondContact CB-O 3.33Å; T221-I374 HydrophobicContact CG2-CG2 4Å; T221-I374 WeakPolarHBondContact CG2-O 3.38Å; T221-V377 HydrophobicContact CG2-CB 4.38Å; T221-V377 HydrophobicContact CG2-CG1 4.13Å; T221-G378 VanDerWaalsContact OG1-CA 3.32Å; T221-G378 WeakPolarHBondContact OG1-CA 3.49Å
222	F	95.8	Very high	94.5	Very high	3 Å²	3	45.9 Å²	45.9	1%	0.013	25%	0.247	C	C	.	.	H	α-helix	trans	-72.6	-27.8	-178.6	-54.2	-51.7	0	0	0	111.9	I90 M218 E225 Y226 I310 F313 V314 W375 I379	I90-F222 HydrophobicContact CD1-CE2 3.99Å; I90-F222 HydrophobicContact CD1-CZ 3.96Å; M218-F222 HydrophobicContact CB-CD2 3.98Å; M218-F222 HydrophobicContact CB-CE2 3.84Å; M218-F222 HydrophobicContact CG-CE2 3.98Å; M218-F222 WeakPolarHBondContact O-CB 3.41Å; M218-F222 WeakPolarHBondContact O-CD2 3.49Å; M218-F222 PolarHBondContact O-N 3.38Å; M218-F222 HydrophobicContact SD-CE2 4.46Å; F222-E225 PolarHBondContact O-N 3.45Å; F222-Y226 PolarHBondContact O-N 2.94Å; F222-I310 HydrophobicContact CB-CG2 4.26Å; F222-I310 HydrophobicContact CD2-CG2 3.53Å; F222-I310 HydrophobicContact CE2-CG2 4.32Å; F222-I310 HydrophobicContact CG-CG2 4.3Å; F222-F313 HydrophobicContact CB-CB 4.45Å; F222-V314 HydrophobicContact CB-CG2 4.36Å; F222-V314 HydrophobicContact CD1-CG2 4.29Å; F222-V314 HydrophobicContact CD2-CG2 4.47Å; F222-V314 HydrophobicContact CG-CG2 4.13Å; F222-W375 AromaticContact CD1-CE3 3.82Å; F222-W375 HydrophobicContact CD1-CE3 3.82Å; F222-W375 AromaticContact CD1-CZ3 3.76Å; F222-W375 HydrophobicContact CD1-CZ3 3.76Å; F222-W375 HydrophobicContact CE1-CD2 4.38Å; F222-W375 AromaticContact CE1-CE3 3.5Å; F222-W375 HydrophobicContact CE1-CE3 3.5Å; F222-W375 VanDerWaalsContact CE1-CE3 3.5Å; F222-W375 HydrophobicContact CE1-CH2 4.38Å; F222-W375 AromaticContact CE1-CZ3 3.47Å; F222-W375 HydrophobicContact CE1-CZ3 3.47Å; F222-W375 VanDerWaalsContact CE1-CZ3 3.47Å; F222-W375 HydrophobicContact CZ-CZ3 4.49Å; F222-I379 HydrophobicContact CZ-CD1 4.24Å
223	G	96.3	Very high	94.5	Very high	13 Å²	13	49.3 Å²	49.3	13%	0.134	26%	0.256	C	S	.	.	H	α-helix	trans	-66.7	-36.4	168.5	0	0	0	0	0	113.6	A219 T221 Y226 V227	A219-G223 WeakPolarHBondContact O-CA 3.43Å; A219-G223 PolarHBondContact O-N 3.02Å; A219-G223 VanDerWaalsContact O-N 3.13Å; T221-G223 VanDerWaalsContact C-N 3.31Å; T221-G223 PolarHBondContact O-N 3Å; G223-Y226 PolarHBondContact O-N 3.38Å; G223-V227 WeakPolarHBondContact O-CG2 3.18Å; G223-V227 PolarHBondContact O-N 3.37Å
224	Y	96	Very high	94.4	Very high	111 Å²	111	48.3 Å²	48.3	44%	0.435	26%	0.264	S	S	.	.	H	α-helix	trans	-65	-44	173	178.5	-88.5	0	0	0	111.7	L220 T221 Y226 V227 T228 I374	L220-Y224 VanDerWaalsContact O-CB 3.29Å; L220-Y224 WeakPolarHBondContact O-CB 3.35Å; L220-Y224 PolarHBondContact O-N 3.31Å; T221-Y224 WeakPolarHBondContact O-CB 3.36Å; T221-Y224 PolarHBondContact O-N 3.11Å; T221-Y224 VanDerWaalsContact O-N 3.17Å; Y224-Y226 PolarHBondContact O-N 3.23Å; Y224-V227 PolarHBondContact O-N 2.69Å; Y224-T228 WeakPolarHBondContact CE1-OG1 3.39Å; Y224-T228 VanDerWaalsContact O-CB 3.29Å; Y224-T228 WeakPolarHBondContact O-CB 3.45Å; Y224-T228 PolarHBondContact O-N 3.07Å; Y224-T228 PolarHBondContact O-OG1 2.98Å; Y224-I374 HydrophobicContact CD1-CD1 3.47Å; Y224-I374 VanDerWaalsContact CD1-CD1 3.47Å; Y224-I374 HydrophobicContact CD1-CG2 4.06Å; Y224-I374 HydrophobicContact CE1-CD1 3.43Å; Y224-I374 VanDerWaalsContact CE1-CD1 3.43Å; Y224-I374 HydrophobicContact CG-CD1 4.09Å
225	E	94.3	Very high	94.3	Very high	2 Å²	2	52.6 Å²	52.6	1%	0.009	28%	0.284	C	S	.	.	H	α-helix	trans	-58.1	-48.1	174.2	-64.5	-50	126.6	0	0	111.1	T221 F222 V227 T228 V229 V317 A371 I374	T221-E225 PolarHBondContact O-N 2.87Å; T221-E225 VanDerWaalsContact O-N 3.12Å; F222-E225 PolarHBondContact O-N 3.45Å; E225-V227 PolarHBondContact O-N 3.44Å; E225-T228 PolarHBondContact O-N 2.95Å; E225-T228 VanDerWaalsContact O-N 3.09Å; E225-V229 WeakPolarHBondContact O-CB 3.42Å; E225-V229 VanDerWaalsContact O-CG2 3.29Å; E225-V229 WeakPolarHBondContact O-CG2 3.37Å; E225-V229 PolarHBondContact O-N 3.06Å; E225-V317 HydrophobicContact CB-CG1 4.41Å; E225-V317 HydrophobicContact CB-CG2 3.91Å; E225-A371 WeakPolarHBondContact OE1-CA 3.42Å; E225-A371 WeakPolarHBondContact OE2-CB 3.43Å; E225-I374 WeakPolarHBondContact OE1-CG2 3.22Å
226	Y	95.6	Very high	94.2	Very high	28 Å²	28	52.5 Å²	52.5	11%	0.11	28%	0.283	C	S	.	.	H	α-helix	trans	-57.6	-43.8	177.5	-173.8	-94	0	0	0	112.9	F222 G223 Y224 T228 K230 P231 Q233 F313	F222-Y226 PolarHBondContact O-N 2.94Å; G223-Y226 PolarHBondContact O-N 3.38Å; Y224-Y226 PolarHBondContact O-N 3.23Å; Y226-T228 VanDerWaalsContact C-N 3.32Å; Y226-T228 PolarHBondContact O-N 3.43Å; Y226-K230 PolarHBondContact O-N 2.97Å; Y226-P231 HydrophobicContact CD2-CG 3.57Å; Y226-P231 HydrophobicContact CE2-CG 3.43Å; Y226-P231 VanDerWaalsContact CE2-CG 3.43Å; Y226-P231 HydrophobicContact CG-CG 4.24Å; Y226-P231 WeakPolarHBondContact O-CD 3.47Å; Y226-Q233 VanDerWaalsContact CZ-NE2 3.34Å; Y226-Q233 VanDerWaalsContact OH-CD 3.23Å; Y226-Q233 PolarHBondContact OH-NE2 3.2Å; Y226-Q233 PolarHBondContact OH-OE1 3.41Å; Y226-F313 AromaticContact CD1-CD1 3.85Å; Y226-F313 HydrophobicContact CD1-CD1 3.85Å; Y226-F313 AromaticContact CD1-CE1 3.91Å; Y226-F313 HydrophobicContact CD1-CE1 3.91Å; Y226-F313 HydrophobicContact CD2-CB 4.15Å; Y226-F313 AromaticContact CD2-CD1 3.58Å; Y226-F313 HydrophobicContact CD2-CD1 3.58Å; Y226-F313 HydrophobicContact CD2-CE1 4.42Å; Y226-F313 HydrophobicContact CD2-CG 4.22Å; Y226-F313 HydrophobicContact CE1-CD1 4.2Å; Y226-F313 HydrophobicContact CE1-CE1 4.11Å; Y226-F313 AromaticContact CE2-CD1 3.92Å; Y226-F313 HydrophobicContact CE2-CD1 3.92Å; Y226-F313 HydrophobicContact CG-CB 4.33Å; Y226-F313 AromaticContact CG-CD1 3.52Å; Y226-F313 HydrophobicContact CG-CD1 3.52Å; Y226-F313 HydrophobicContact CG-CE1 4.07Å; Y226-F313 HydrophobicContact CG-CG 4.11Å
227	V	94.9	Very high	94.1	Very high	100 Å²	100	53.5 Å²	53.5	61%	0.606	29%	0.285	S	S	*	.	H	α-helix	trans	-71.1	-26.6	177.7	172	0	0	0	0	112.7	G223 Y224 E225 K230	G223-V227 WeakPolarHBondContact O-CG2 3.18Å; G223-V227 PolarHBondContact O-N 3.37Å; Y224-V227 PolarHBondContact O-N 2.69Å; E225-V227 PolarHBondContact O-N 3.44Å; V227-K230 WeakPolarHBondContact O-CE 3.21Å; V227-K230 WeakPolarHBondContact O-CG 3.41Å
228	T	93.4	Very high	93.8	Very high	39 Å²	39	58.3 Å²	58.3	24%	0.239	30%	0.304	C	S	.	.	H	α-helix	trans	-80.7	-47.5	179.7	-62.2	0	0	0	0	111.7	Y224 E225 Y226 F367	Y224-T228 WeakPolarHBondContact CE1-OG1 3.39Å; Y224-T228 VanDerWaalsContact O-CB 3.29Å; Y224-T228 WeakPolarHBondContact O-CB 3.45Å; Y224-T228 PolarHBondContact O-N 3.07Å; Y224-T228 PolarHBondContact O-OG1 2.98Å; E225-T228 PolarHBondContact O-N 2.95Å; E225-T228 VanDerWaalsContact O-N 3.09Å; Y226-T228 VanDerWaalsContact C-N 3.32Å; Y226-T228 PolarHBondContact O-N 3.43Å; T228-F367 HydrophobicContact CG2-CB 4.1Å; T228-F367 HydrophobicContact CG2-CD1 4.22Å; T228-F367 HydrophobicContact CG2-CG 4.42Å
229	V	91.8	Very high	93.4	Very high	14 Å²	14	58.8 Å²	58.8	9%	0.085	31%	0.309	C	S	.	.	H	α-helix	trans	-71	-29.7	178.9	176.8	0	0	0	0	112.1	E225 V317 E320 L363 F367	E225-V229 WeakPolarHBondContact O-CB 3.42Å; E225-V229 VanDerWaalsContact O-CG2 3.29Å; E225-V229 WeakPolarHBondContact O-CG2 3.37Å; E225-V229 PolarHBondContact O-N 3.06Å; V229-V317 HydrophobicContact CB-CG2 4.38Å; V229-V317 HydrophobicContact CG2-CG1 4.18Å; V229-V317 HydrophobicContact CG2-CG2 4.3Å; V229-E320 HydrophobicContact CG1-CB 3.98Å; V229-E320 HydrophobicContact CG1-CG 4.31Å; V229-L363 HydrophobicContact CG2-CD2 4.34Å; V229-F367 HydrophobicContact CB-CE1 4.32Å; V229-F367 HydrophobicContact CB-CZ 4.17Å; V229-F367 HydrophobicContact CG1-CE1 4.48Å; V229-F367 HydrophobicContact CG1-CE2 4.5Å; V229-F367 HydrophobicContact CG1-CZ 3.97Å; V229-F367 HydrophobicContact CG2-CD1 4.26Å; V229-F367 HydrophobicContact CG2-CD2 3.97Å; V229-F367 HydrophobicContact CG2-CE1 4.01Å; V229-F367 HydrophobicContact CG2-CE2 3.72Å; V229-F367 HydrophobicContact CG2-CG 4.26Å; V229-F367 HydrophobicContact CG2-CZ 3.74Å
230	K	92.6	Very high	93.1	Very high	162 Å²	162	58.3 Å²	58.3	70%	0.704	30%	0.302	S	S	*	.			trans	55.4	53.1	177	-58.7	168.9	-172.7	163.6	0	113.4	Y226 V227	Y226-K230 PolarHBondContact O-N 2.97Å; V227-K230 WeakPolarHBondContact O-CE 3.21Å; V227-K230 WeakPolarHBondContact O-CG 3.41Å
231	P	91.9	Very high	92.8	Very high	3 Å²	3	59 Å²	59	2%	0.019	30%	0.3	C	S	.	.			trans	-58.2	148.3	179.1	27.9	-34.4	0	0	0	111.1	F102 Y226 Q233 V236 E320	F102-P231 HydrophobicContact CE1-CB 4.16Å; F102-P231 HydrophobicContact CZ-CB 4.17Å; Y226-P231 HydrophobicContact CD2-CG 3.57Å; Y226-P231 HydrophobicContact CE2-CG 3.43Å; Y226-P231 VanDerWaalsContact CE2-CG 3.43Å; Y226-P231 HydrophobicContact CG-CG 4.24Å; Y226-P231 WeakPolarHBondContact O-CD 3.47Å; P231-Q233 PolarHBondContact O-N 3Å; P231-Q233 PolarHBondContact O-NE2 3.47Å; P231-V236 HydrophobicContact CB-CG2 4.42Å; P231-E320 VanDerWaalsContact CA-OE2 3.32Å; P231-E320 WeakPolarHBondContact CA-OE2 3.19Å; P231-E320 HydrophobicContact CB-CB 3.95Å; P231-E320 HydrophobicContact CB-CG 4.32Å
232	S	92.6	Very high	92.4	Very high	38 Å²	38	61.9 Å²	61.9	27%	0.266	32%	0.317	S	S	.	.			trans	-68.9	99.3	-172.1	47.4	0	0	0	0	112.3	S234 Q235 V236 E320	S232-S234 PolarHBondContact O-N 3.12Å; S232-Q235 WeakPolarHBondContact O-CA 3.03Å; S232-Q235 WeakPolarHBondContact O-CB 3.4Å; S232-Q235 PolarHBondContact O-N 2.89Å; S232-Q235 WeakPolarHBondContact OG-CG 3.42Å; S232-Q235 PolarHBondContact OG-NE2 3.44Å; S232-V236 PolarHBondContact O-N 3.32Å; S232-V236 VanDerWaalsContact O-N 3.17Å; S232-E320 PolarHBondContact N-OE2 3.4Å; S232-E320 PolarHBondContact OG-OE2 3.42Å; S232-E320 VanDerWaalsContact OG-OE2 3.09Å
233	Q	92.5	Very high	91.7	Very high	97 Å²	97	66.1 Å²	66.1	45%	0.453	35%	0.345	S	S	.	.	H	α-helix	trans	-52.7	-32.4	-170.7	-56.4	-60.5	-71.5	0	0	114.5	Y226 P231 V236 L237	Y226-Q233 VanDerWaalsContact CZ-NE2 3.34Å; Y226-Q233 VanDerWaalsContact OH-CD 3.23Å; Y226-Q233 PolarHBondContact OH-NE2 3.2Å; Y226-Q233 PolarHBondContact OH-OE1 3.41Å; P231-Q233 PolarHBondContact O-N 3Å; P231-Q233 PolarHBondContact O-NE2 3.47Å; Q233-V236 PolarHBondContact O-N 3.39Å; Q233-L237 WeakPolarHBondContact O-CB 3.45Å; Q233-L237 WeakPolarHBondContact O-CG 3.25Å; Q233-L237 PolarHBondContact O-N 2.88Å
234	S	91.3	Very high	90.5	Very high	97 Å²	97	68.6 Å²	68.6	68%	0.678	36%	0.361	S	S	*	.	H	α-helix	trans	-65.8	-36.8	174.4	-176.7	0	0	0	0	112.6	S232 K238	S232-S234 PolarHBondContact O-N 3.12Å; S234-K238 WeakPolarHBondContact O-CB 3.04Å; S234-K238 PolarHBondContact O-N 3.36Å
235	Q	90.6	Very high	89.3	Confident	103 Å²	103	65.8 Å²	65.8	48%	0.481	36%	0.356	S	S	.	.	H	α-helix	trans	-73.3	-39.6	174.8	-58.9	-162	64.2	0	0	111.8	F102 S232 K238 G239	F102-Q235 HydrophobicContact CB-CB 4.5Å; F102-Q235 HydrophobicContact CD2-CB 3.56Å; F102-Q235 HydrophobicContact CD2-CG 4.45Å; F102-Q235 HydrophobicContact CE2-CB 3.91Å; F102-Q235 HydrophobicContact CG-CB 3.99Å; S232-Q235 WeakPolarHBondContact O-CA 3.03Å; S232-Q235 WeakPolarHBondContact O-CB 3.4Å; S232-Q235 PolarHBondContact O-N 2.89Å; S232-Q235 WeakPolarHBondContact OG-CG 3.42Å; S232-Q235 PolarHBondContact OG-NE2 3.44Å; Q235-K238 PolarHBondContact O-N 3.38Å; Q235-G239 PolarHBondContact O-N 3.07Å
236	V	92.9	Very high	87.9	Confident	4 Å²	4	69.3 Å²	69.3	2%	0.024	38%	0.381	C	S	.	.	H	α-helix	trans	-57.4	-56.4	174.1	179.9	0	0	0	0	110.3	F102 L105 P231 S232 Q233 K238 G239 M240 V312	F102-V236 HydrophobicContact CD1-CG2 3.81Å; F102-V236 HydrophobicContact CE1-CG2 3.65Å; L105-V236 HydrophobicContact CD1-CB 4.5Å; L105-V236 HydrophobicContact CD1-CG1 4.07Å; P231-V236 HydrophobicContact CB-CG2 4.42Å; S232-V236 PolarHBondContact O-N 3.32Å; S232-V236 VanDerWaalsContact O-N 3.17Å; Q233-V236 PolarHBondContact O-N 3.39Å; V236-K238 VanDerWaalsContact C-N 3.34Å; V236-K238 PolarHBondContact O-N 2.69Å; V236-G239 PolarHBondContact O-N 3.08Å; V236-G239 VanDerWaalsContact O-N 3.13Å; V236-M240 HydrophobicContact CG1-SD 3.89Å; V236-M240 VanDerWaalsContact O-CG 3.3Å; V236-M240 WeakPolarHBondContact O-CG 3.2Å; V236-M240 PolarHBondContact O-N 3.12Å; V236-V312 HydrophobicContact CG1-CG1 4.02Å
237	L	92.6	Very high	86.4	Confident	99 Å²	99	71.4 Å²	71.4	52%	0.518	41%	0.412	S	S	.	.	H	α-helix	trans	-60.6	-40.5	178.8	-73.5	169.6	0	0	0	112.7	Q233 M240 F241	Q233-L237 WeakPolarHBondContact O-CB 3.45Å; Q233-L237 WeakPolarHBondContact O-CG 3.25Å; Q233-L237 PolarHBondContact O-N 2.88Å; L237-M240 PolarHBondContact O-N 3.38Å; L237-F241 HydrophobicContact CD2-CD2 4.5Å; L237-F241 HydrophobicContact CD2-CE2 4.12Å; L237-F241 WeakPolarHBondContact O-CD2 3.31Å; L237-F241 PolarHBondContact O-N 3.48Å
238	K	90.3	Very high	85.5	Confident	141 Å²	141	68.1 Å²	68.1	61%	0.613	39%	0.393	S	S	*	.	H	α-helix	trans	-63.8	-42.3	175.3	-174.3	179.7	-179.7	-177.6	0	111.5	S234 Q235 V236 V242	S234-K238 WeakPolarHBondContact O-CB 3.04Å; S234-K238 PolarHBondContact O-N 3.36Å; Q235-K238 PolarHBondContact O-N 3.38Å; V236-K238 VanDerWaalsContact C-N 3.34Å; V236-K238 PolarHBondContact O-N 2.69Å; K238-V242 HydrophobicContact CG-CB 4.29Å; K238-V242 HydrophobicContact CG-CG2 4.02Å; K238-V242 VanDerWaalsContact O-CB 3.24Å; K238-V242 WeakPolarHBondContact O-CB 3.33Å; K238-V242 PolarHBondContact O-N 2.96Å
239	G	87.7	Confident	84.7	Confident	10 Å²	10	75.5 Å²	75.5	10%	0.103	42%	0.416	C	S	.	.	H	α-helix	trans	-65.2	-34.5	178.1	0	0	0	0	0	113.8	F102 W106 Q235 V236	F102-G239 WeakPolarHBondContact O-CA 3.27Å; W106-G239 WeakPolarHBondContact CB-O 3.43Å; W106-G239 PolarHBondContact N-O 2.92Å; Q235-G239 PolarHBondContact O-N 3.07Å; V236-G239 PolarHBondContact O-N 3.08Å; V236-G239 VanDerWaalsContact O-N 3.13Å
240	M	89.1	Confident	84	Confident	23 Å²	23	78.5 Å²	78.5	11%	0.113	43%	0.434	C	S	.	.	H	α-helix	trans	-71.7	-41.6	176.7	-68.5	165.3	70.8	0	0	113.2	L105 W106 V236 L237 F308 V312	L105-M240 HydrophobicContact CB-CG 3.92Å; L105-M240 HydrophobicContact CD1-CG 4.2Å; W106-M240 WeakPolarHBondContact CA-O 3.34Å; W106-M240 VanDerWaalsContact CB-O 3.27Å; W106-M240 WeakPolarHBondContact CB-O 3.43Å; V236-M240 HydrophobicContact CG1-SD 3.89Å; V236-M240 VanDerWaalsContact O-CG 3.3Å; V236-M240 WeakPolarHBondContact O-CG 3.2Å; V236-M240 PolarHBondContact O-N 3.12Å; L237-M240 PolarHBondContact O-N 3.38Å; M240-F308 HydrophobicContact CE-CE1 3.8Å; M240-F308 HydrophobicContact CE-CZ 3.87Å; M240-V312 HydrophobicContact SD-CG1 4.32Å
241	F	90.7	Very high	83.3	Confident	138 Å²	138	73.6 Å²	73.6	61%	0.605	42%	0.419	S	S	*	.	H	α-helix	trans	-109.3	-12.6	-168.3	-66.3	-68.4	0	0	0	115.4	L109 L237 P243	L109-F241 HydrophobicContact CD2-CD1 4.37Å; L109-F241 HydrophobicContact CD2-CE1 4.14Å; L237-F241 HydrophobicContact CD2-CD2 4.5Å; L237-F241 HydrophobicContact CD2-CE2 4.12Å; L237-F241 WeakPolarHBondContact O-CD2 3.31Å; L237-F241 PolarHBondContact O-N 3.48Å; F241-P243 WeakPolarHBondContact O-CD 3.25Å
242	V	87	Confident	82.9	Confident	74 Å²	74	75.2 Å²	75.2	45%	0.448	43%	0.427	S	S	.	.			trans	-110.6	101	179.2	-172.5	0	0	0	0	110	K238 S244	K238-V242 HydrophobicContact CG-CB 4.29Å; K238-V242 HydrophobicContact CG-CG2 4.02Å; K238-V242 VanDerWaalsContact O-CB 3.24Å; K238-V242 WeakPolarHBondContact O-CB 3.33Å; K238-V242 PolarHBondContact O-N 2.96Å; V242-S244 PolarHBondContact O-N 2.89Å
243	P	81.6	Confident	82.3	Confident	92 Å²	92	78.2 Å²	78.2	60%	0.597	44%	0.439	S	S	*	.			trans	-69	95.1	178.4	28.2	-34.2	0	0	0	110.5	W106 F241	W106-P243 HydrophobicContact CD2-CB 3.8Å; W106-P243 HydrophobicContact CE3-CB 3.95Å; W106-P243 HydrophobicContact CG-CB 4.24Å; W106-P243 HydrophobicContact CH2-CB 4.49Å; W106-P243 HydrophobicContact CZ2-CB 4.36Å; W106-P243 HydrophobicContact CZ3-CB 4.29Å; F241-P243 WeakPolarHBondContact O-CD 3.25Å
244	S	71.1	Confident	81.6	Confident	66 Å²	66	77.8 Å²	77.8	46%	0.462	44%	0.436	S	S	.	.			trans	-149.4	98.5	-177.2	-165.2	0	0	0	0	112.3	V242 S246	V242-S244 PolarHBondContact O-N 2.89Å; S244-S246 VanDerWaalsContact C-N 3.33Å; S244-S246 PolarHBondContact O-N 2.93Å
245	C	70	Confident	81.3	Confident	51 Å²	51	74.7 Å²	74.7	35%	0.345	41%	0.411	S	S	.	.			trans	-92.5	59.1	176.8	-140.7	0	0	0	0	111.2	G247 C248	C245-G247 PolarHBondContact O-N 3.07Å; C245-C248 WeakPolarHBondContact CA-SG 3.3Å; C245-C248 HydrophobicContact CB-CB 3.81Å; C245-C248 WeakPolarHBondContact CB-SG 3.48Å; C245-C248 PolarHBondContact O-N 3.24Å; C245-C248 PolarHBondContact O-SG 3.49Å; C245-C248 VanDerWaalsContact O-SG 3.33Å; C245-C248 WeakPolarHBondContact SG-CB 3.38Å; C245-C248 CovalentContact SG-SG 2.03Å; C245-C248 PolarHBondContact SG-SG 3.26Å
246	S	65.4	Low	80.9	Confident	77 Å²	77	70.6 Å²	70.6	54%	0.538	40%	0.395	S	S	.	.	T	Hydrogen-bonded Turn	trans	-63.3	118	-176.8	55.6	0	0	0	0	111.6	K103 S244 C248	K103-S246 PolarHBondContact NZ-O 3.04Å; S244-S246 VanDerWaalsContact C-N 3.33Å; S244-S246 PolarHBondContact O-N 2.93Å; S246-C248 VanDerWaalsContact C-N 3.34Å; S246-C248 PolarHBondContact O-N 2.84Å
247	G	65.6	Low	80.3	Confident	72 Å²	72	71.5 Å²	71.5	74%	0.742	40%	0.4	S	S	*	.	T	Hydrogen-bonded Turn	trans	72.9	17.3	-179.4	0	0	0	0	0	115.7	C245	C245-G247 PolarHBondContact O-N 3.07Å
248	C	74.1	Confident	79.7	Confident	31 Å²	31	67.7 Å²	67.7	21%	0.209	39%	0.385	C	S	.	.			trans	-66.1	137.7	175.9	-66.5	0	0	0	0	112	C245 S246 Q252	C245-C248 WeakPolarHBondContact CA-SG 3.3Å; C245-C248 HydrophobicContact CB-CB 3.81Å; C245-C248 WeakPolarHBondContact CB-SG 3.48Å; C245-C248 PolarHBondContact O-N 3.24Å; C245-C248 PolarHBondContact O-SG 3.49Å; C245-C248 VanDerWaalsContact O-SG 3.33Å; C245-C248 WeakPolarHBondContact SG-CB 3.38Å; C245-C248 CovalentContact SG-SG 2.03Å; C245-C248 PolarHBondContact SG-SG 3.26Å; S246-C248 VanDerWaalsContact C-N 3.34Å; S246-C248 PolarHBondContact O-N 2.84Å; C248-Q252 HydrophobicContact CB-CB 3.88Å; C248-Q252 HydrophobicContact CB-CG 4.48Å
249	R	77.8	Confident	79.5	Confident	194 Å²	194	61 Å²	61	73%	0.732	36%	0.356	S	S	*	.			trans	-114.8	-176.4	176.6	-61.2	177.8	179.9	171.5	-1.1	109.4	Q252 I253	R249-Q252 PolarHBondContact O-N 3.17Å; R249-Q252 PolarHBondContact O-OE1 3.37Å; R249-I253 PolarHBondContact O-N 3.25Å
250	T	76.4	Confident	79.3	Confident	76 Å²	76	62.2 Å²	62.2	47%	0.466	36%	0.362	S	S	.	.	H	α-helix	trans	-46.6	-47.9	179.9	-11	0	0	0	0	113.7	Q252 I253 E254	T250-Q252 VanDerWaalsContact C-N 3.32Å; T250-Q252 PolarHBondContact O-N 3.06Å; T250-I253 CarbonylContact O-C 3.59Å; T250-I253 WeakPolarHBondContact O-CA 3.45Å; T250-I253 WeakPolarHBondContact O-CB 2.99Å; T250-I253 PolarHBondContact O-N 2.96Å; T250-E254 WeakPolarHBondContact CB-OE1 3.21Å; T250-E254 WeakPolarHBondContact CG2-OE1 3.47Å; T250-E254 WeakPolarHBondContact O-CG 3.21Å; T250-E254 PolarHBondContact O-N 3.16Å
251	P	77.8	Confident	78.8	Confident	59 Å²	59	61.1 Å²	61.1	38%	0.383	36%	0.356	S	S	.	.	H	α-helix	trans	-60.7	-33.8	180	-27.2	37.1	0	0	0	114.9	V99 I253 E254 Q255	V99-P251 HydrophobicContact CG1-CB 4.15Å; P251-I253 VanDerWaalsContact C-N 3.31Å; P251-E254 WeakPolarHBondContact CA-OE2 3.47Å; P251-Q255 WeakPolarHBondContact O-CB 3.44Å; P251-Q255 VanDerWaalsContact O-CG 3.25Å; P251-Q255 WeakPolarHBondContact O-CG 3.44Å; P251-Q255 PolarHBondContact O-N 2.92Å; P251-Q255 VanDerWaalsContact O-N 3.09Å
252	Q	83	Confident	78.5	Confident	38 Å²	38	54.6 Å²	54.6	18%	0.178	33%	0.327	C	S	.	.	H	α-helix	trans	-75.3	-21.7	174.7	-69.6	83	29.3	0	0	112.7	V99 A100 C248 R249 T250 A256	V99-Q252 HydrophobicContact CG1-CG 4.4Å; V99-Q252 PolarHBondContact O-NE2 3.21Å; A100-Q252 HydrophobicContact CB-CB 4.47Å; A100-Q252 HydrophobicContact CB-CG 3.81Å; C248-Q252 HydrophobicContact CB-CB 3.88Å; C248-Q252 HydrophobicContact CB-CG 4.48Å; R249-Q252 PolarHBondContact O-N 3.17Å; R249-Q252 PolarHBondContact O-OE1 3.37Å; T250-Q252 VanDerWaalsContact C-N 3.32Å; T250-Q252 PolarHBondContact O-N 3.06Å; Q252-A256 VanDerWaalsContact O-CB 3.29Å; Q252-A256 WeakPolarHBondContact O-CB 3.41Å; Q252-A256 PolarHBondContact O-N 2.82Å; Q252-A256 VanDerWaalsContact O-N 3.13Å
253	I	80.6	Confident	78.6	Confident	101 Å²	101	51 Å²	51	52%	0.518	31%	0.306	S	S	.	.	H	α-helix	trans	-85.6	-38.5	177.2	-62.9	167.9	0	0	0	110.4	R249 T250 P251 A256 V257	R249-I253 PolarHBondContact O-N 3.25Å; T250-I253 CarbonylContact O-C 3.59Å; T250-I253 WeakPolarHBondContact O-CA 3.45Å; T250-I253 WeakPolarHBondContact O-CB 2.99Å; T250-I253 PolarHBondContact O-N 2.96Å; P251-I253 VanDerWaalsContact C-N 3.31Å; I253-A256 WeakPolarHBondContact O-CB 3.42Å; I253-A256 PolarHBondContact O-N 3.11Å; I253-V257 PolarHBondContact O-N 3.07Å
254	E	78.5	Confident	78.8	Confident	87 Å²	87	46.9 Å²	46.9	41%	0.407	28%	0.279	S	S	.	.	H	α-helix	trans	-59.4	-50.6	170.6	-72.2	148.2	-160.7	0	0	110.3	T250 P251 A256 V257 G258	T250-E254 WeakPolarHBondContact CB-OE1 3.21Å; T250-E254 WeakPolarHBondContact CG2-OE1 3.47Å; T250-E254 WeakPolarHBondContact O-CG 3.21Å; T250-E254 PolarHBondContact O-N 3.16Å; P251-E254 WeakPolarHBondContact CA-OE2 3.47Å; E254-A256 VanDerWaalsContact C-N 3.33Å; E254-A256 PolarHBondContact O-N 3Å; E254-V257 PolarHBondContact O-N 2.99Å; E254-V257 VanDerWaalsContact O-N 3.07Å; E254-G258 PolarHBondContact O-N 3.42Å
255	Q	83.6	Confident	79.7	Confident	33 Å²	33	43.8 Å²	43.8	15%	0.154	26%	0.257	C	S	.	.	H	α-helix	trans	-62	-36.3	173.9	-73.5	-70.2	-28.7	0	0	112.9	V99 L104 P251 V257 G258 I259	V99-Q255 HydrophobicContact CB-CG 4.27Å; V99-Q255 HydrophobicContact CG1-CG 4.19Å; V99-Q255 HydrophobicContact CG2-CG 4.47Å; L104-Q255 HydrophobicContact CD1-CB 4.03Å; P251-Q255 WeakPolarHBondContact O-CB 3.44Å; P251-Q255 VanDerWaalsContact O-CG 3.25Å; P251-Q255 WeakPolarHBondContact O-CG 3.44Å; P251-Q255 PolarHBondContact O-N 2.92Å; P251-Q255 VanDerWaalsContact O-N 3.09Å; Q255-V257 VanDerWaalsContact C-N 3.27Å; Q255-V257 PolarHBondContact O-N 3.48Å; Q255-G258 PolarHBondContact O-N 3.14Å; Q255-I259 WeakPolarHBondContact O-CG1 3.49Å; Q255-I259 PolarHBondContact O-N 2.94Å
256	A	83.7	Confident	80.5	Confident	16 Å²	16	41.4 Å²	41.4	13%	0.132	24%	0.241	C	C	.	.	H	α-helix	trans	-61.6	-33.1	172.9	0	0	0	0	0	113.2	L104 I107 Q252 I253 E254	L104-A256 HydrophobicContact CD2-CB 4.07Å; I107-A256 HydrophobicContact CD1-CB 3.58Å; Q252-A256 VanDerWaalsContact O-CB 3.29Å; Q252-A256 WeakPolarHBondContact O-CB 3.41Å; Q252-A256 PolarHBondContact O-N 2.82Å; Q252-A256 VanDerWaalsContact O-N 3.13Å; I253-A256 WeakPolarHBondContact O-CB 3.42Å; I253-A256 PolarHBondContact O-N 3.11Å; E254-A256 VanDerWaalsContact C-N 3.33Å; E254-A256 PolarHBondContact O-N 3Å
257	V	79.4	Confident	81.7	Confident	23 Å²	23	37.8 Å²	37.8	14%	0.139	22%	0.215	C	C	.	.	H	α-helix	trans	-77.5	-38.3	172.3	171.5	0	0	0	0	111.5	I253 E254 Q255 I259 V260 G261 I490 F494	I253-V257 PolarHBondContact O-N 3.07Å; E254-V257 PolarHBondContact O-N 2.99Å; E254-V257 VanDerWaalsContact O-N 3.07Å; Q255-V257 VanDerWaalsContact C-N 3.27Å; Q255-V257 PolarHBondContact O-N 3.48Å; V257-I259 VanDerWaalsContact C-N 3.33Å; V257-I259 PolarHBondContact O-N 2.97Å; V257-V260 PolarHBondContact O-N 3.02Å; V257-G261 PolarHBondContact O-N 3.43Å; V257-I490 HydrophobicContact CB-CG2 4.24Å; V257-I490 HydrophobicContact CG1-CG2 3.42Å; V257-I490 VanDerWaalsContact CG1-CG2 3.42Å; V257-I490 HydrophobicContact CG2-CD1 4.48Å; V257-I490 HydrophobicContact CG2-CG2 3.72Å; V257-F494 HydrophobicContact CB-CE2 3.91Å; V257-F494 HydrophobicContact CB-CZ 4.15Å; V257-F494 HydrophobicContact CG1-CD2 4.28Å; V257-F494 HydrophobicContact CG1-CE2 3.56Å; V257-F494 HydrophobicContact CG1-CZ 3.98Å; V257-F494 HydrophobicContact CG2-CE2 4.11Å
258	G	80.5	Confident	82.9	Confident	20 Å²	20	34.3 Å²	34.3	21%	0.206	18%	0.18	C	C	.	.	H	α-helix	trans	-51	-50.6	174.2	0	0	0	0	0	112	S92 E254 Q255 V260 G261 A262	S92-G258 VanDerWaalsContact OG-C 3.23Å; E254-G258 PolarHBondContact O-N 3.42Å; Q255-G258 PolarHBondContact O-N 3.14Å; G258-V260 VanDerWaalsContact C-N 3.31Å; G258-V260 PolarHBondContact O-N 3.04Å; G258-G261 PolarHBondContact O-N 2.92Å; G258-G261 VanDerWaalsContact O-N 3.13Å; G258-A262 WeakPolarHBondContact O-CB 3.41Å; G258-A262 PolarHBondContact O-N 3.23Å
259	I	86.2	Confident	83.8	Confident	0 Å²	0	33 Å²	33	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-54	-46.6	174.9	-62.7	164.7	0	0	0	111.1	S92 L104 L108 A111 Q255 V257 G261 A262 V263	S92-I259 PolarHBondContact OG-N 3.25Å; L104-I259 HydrophobicContact CB-CD1 3.7Å; L104-I259 HydrophobicContact CD1-CD1 4.07Å; L104-I259 HydrophobicContact CG-CD1 4.46Å; L108-I259 HydrophobicContact CB-CG2 4.13Å; L108-I259 HydrophobicContact CD1-CG2 4.23Å; A111-I259 HydrophobicContact CB-CG2 4.36Å; Q255-I259 WeakPolarHBondContact O-CG1 3.49Å; Q255-I259 PolarHBondContact O-N 2.94Å; V257-I259 VanDerWaalsContact C-N 3.33Å; V257-I259 PolarHBondContact O-N 2.97Å; I259-G261 PolarHBondContact O-N 3.22Å; I259-A262 PolarHBondContact O-N 3.24Å; I259-V263 HydrophobicContact CG2-CG2 3.96Å; I259-V263 WeakPolarHBondContact O-CB 3.19Å; I259-V263 WeakPolarHBondContact O-CG2 3.42Å; I259-V263 PolarHBondContact O-N 2.89Å
260	V	83.8	Confident	84.6	Confident	36 Å²	36	23.8 Å²	23.8	22%	0.218	14%	0.136	C	C	.	.	H	α-helix	trans	-66.8	-36.7	-178.5	177	0	0	0	0	111.8	I107 A111 V257 G258 I264	I107-V260 HydrophobicContact CG2-CG2 4.06Å; A111-V260 HydrophobicContact CB-CG2 4.26Å; V257-V260 PolarHBondContact O-N 3.02Å; G258-V260 VanDerWaalsContact C-N 3.31Å; G258-V260 PolarHBondContact O-N 3.04Å; V260-I264 HydrophobicContact CG1-CD1 4.12Å; V260-I264 WeakPolarHBondContact O-CB 3.28Å; V260-I264 WeakPolarHBondContact O-CG1 3.29Å; V260-I264 PolarHBondContact O-N 3.25Å
261	G	79	Confident	85.4	Confident	0 Å²	0	20.2 Å²	20.2	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-68.7	-45.4	175.6	0	0	0	0	0	113	V257 G258 I259	V257-G261 PolarHBondContact O-N 3.43Å; G258-G261 PolarHBondContact O-N 2.92Å; G258-G261 VanDerWaalsContact O-N 3.13Å; I259-G261 PolarHBondContact O-N 3.22Å
262	A	83.9	Confident	86.1	Confident	0 Å²	0	17.4 Å²	17.4	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-75.9	-34.6	-177.5	0	0	0	0	0	113.1	N89 G258 I259	N89-A262 HydrophobicContact CB-CB 4.5Å; N89-A262 PolarHBondContact ND2-O 3.45Å; G258-A262 WeakPolarHBondContact O-CB 3.41Å; G258-A262 PolarHBondContact O-N 3.23Å; I259-A262 PolarHBondContact O-N 3.24Å
263	V	87.8	Confident	86.7	Confident	0 Å²	0	15.6 Å²	15.6	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-76	-20.7	176.5	173.9	0	0	0	0	112.5	Y84 N89 L108 A111 I259	Y84-V263 HydrophobicContact CD1-CG1 3.96Å; Y84-V263 WeakPolarHBondContact CD1-O 2.99Å; Y84-V263 HydrophobicContact CE1-CG1 3.79Å; Y84-V263 WeakPolarHBondContact CE1-O 3.06Å; Y84-V263 VanDerWaalsContact CZ-O 3.3Å; Y84-V263 PolarHBondContact OH-O 2.84Å; N89-V263 WeakPolarHBondContact ND2-CA 3.38Å; L108-V263 HydrophobicContact CD1-CG2 3.77Å; A111-V263 HydrophobicContact CB-CB 3.99Å; A111-V263 HydrophobicContact CB-CG1 3.76Å; A111-V263 HydrophobicContact CB-CG2 4.45Å; I259-V263 HydrophobicContact CG2-CG2 3.96Å; I259-V263 WeakPolarHBondContact O-CB 3.19Å; I259-V263 WeakPolarHBondContact O-CG2 3.42Å; I259-V263 PolarHBondContact O-N 2.89Å
264	I	87.4	Confident	87.2	Confident	5 Å²	5	10.8 Å²	10.8	3%	0.026	6%	0.063	C	C	.	.	S	Bend	trans	-117	69.4	-179.9	-47.3	177.7	0	0	0	109.7	V114 L118 V260 L450	V114-I264 HydrophobicContact CB-CD1 4.43Å; V114-I264 HydrophobicContact CG1-CD1 3.84Å; L118-I264 HydrophobicContact CD1-CD1 4.19Å; L118-I264 HydrophobicContact CD1-CG2 3.54Å; V260-I264 HydrophobicContact CG1-CD1 4.12Å; V260-I264 WeakPolarHBondContact O-CB 3.28Å; V260-I264 WeakPolarHBondContact O-CG1 3.29Å; V260-I264 PolarHBondContact O-N 3.25Å; I264-L450 HydrophobicContact CB-CD2 3.94Å; I264-L450 HydrophobicContact CG2-CD2 3.57Å; I264-L450 WeakPolarHBondContact O-CD2 3.46Å
265	M	88.4	Confident	87.8	Confident	1 Å²	1	7 Å²	7	1%	0.005	5%	0.045	C	C	.	.			trans	-62.7	126.1	179.1	-76	-166.7	150.7	0	0	112.8	A83 D86 H267 N268	A83-M265 HydrophobicContact CB-SD 3.74Å; D86-M265 HydrophobicContact CB-CE 4.46Å; D86-M265 WeakPolarHBondContact OD1-CE 3.33Å; D86-M265 WeakPolarHBondContact OD2-CE 3.49Å; M265-H267 PolarHBondContact O-N 2.94Å; M265-H267 PolarHBondContact SD-CE1 3.04Å; M265-N268 HydrophobicContact CB-CB 3.96Å; M265-N268 PolarHBondContact O-N 3.04Å
266	P	87.6	Confident	88.2	Confident	1 Å²	1	5.6 Å²	5.6	1%	0.006	4%	0.039	C	C	.	.	H	α-helix	trans	-65.4	-42.5	-175.9	-17.1	27.7	0	0	0	112.7	N268 M269 Y270 Q446 Q449 L450 A453	P266-N268 VanDerWaalsContact C-N 3.26Å; P266-N268 PolarHBondContact O-N 2.99Å; P266-M269 WeakPolarHBondContact O-CB 3.19Å; P266-M269 PolarHBondContact O-N 3.22Å; P266-Y270 WeakPolarHBondContact O-CD2 3.47Å; P266-Q446 WeakPolarHBondContact CG-O 3.31Å; P266-Q449 HydrophobicContact CB-CB 4.45Å; P266-Q449 HydrophobicContact CG-CB 3.86Å; P266-L450 HydrophobicContact CG-CG 4.41Å; P266-A453 HydrophobicContact CB-CB 3.75Å; P266-A453 VanDerWaalsContact O-CB 3.26Å; P266-A453 WeakPolarHBondContact O-CB 3.46Å
267	H	90.4	Very high	88.4	Confident	0 Å²	0	6.5 Å²	6.5	0%	0	4%	0.04	C	C	.	.	H	α-helix	trans	-63.8	-33.3	-177.9	71.3	-108.8	0	0	0	112.1	I157 S160 M265 M269 Y270 L271 S393	I157-H267 HydrophobicContact CD1-CB 4.22Å; I157-H267 HydrophobicContact CG1-CB 3.49Å; I157-H267 VanDerWaalsContact CG1-CB 3.49Å; S160-H267 PolarHBondContact OG-CE1 3.16Å; M265-H267 PolarHBondContact O-N 2.94Å; M265-H267 PolarHBondContact SD-CE1 3.04Å; H267-M269 PolarHBondContact O-N 3.07Å; H267-Y270 WeakPolarHBondContact O-CB 3.26Å; H267-Y270 PolarHBondContact O-N 3.25Å; H267-L271 PolarHBondContact O-N 2.7Å; H267-L271 VanDerWaalsContact O-N 3.08Å; H267-S393 PolarHBondContact CD2-OG 2.98Å
268	N	91.7	Very high	88.7	Confident	0 Å²	0	5.5 Å²	5.5	0%	0	3%	0.034	C	C	.	.	H	α-helix	trans	-64.7	-26.9	-177.5	-166.6	4.2	0	0	0	111.9	M80 A83 Y84 Q119 M265 P266 Y270 L271 H272	M80-N268 WeakPolarHBondContact CG-OD1 3.21Å; M80-N268 PolarHBondContact O-ND2 3.36Å; M80-N268 PolarHBondContact O-OD1 2.85Å; A83-N268 HydrophobicContact CB-CB 4.04Å; A83-N268 WeakPolarHBondContact CB-ND2 3.18Å; A83-N268 PolarHBondContact O-ND2 3.27Å; Y84-N268 WeakPolarHBondContact CE2-ND2 3.41Å; Q119-N268 VanDerWaalsContact NE2-CG 3.3Å; Q119-N268 PolarHBondContact NE2-ND2 2.85Å; M265-N268 HydrophobicContact CB-CB 3.96Å; M265-N268 PolarHBondContact O-N 3.04Å; P266-N268 VanDerWaalsContact C-N 3.26Å; P266-N268 PolarHBondContact O-N 2.99Å; N268-Y270 VanDerWaalsContact C-N 3.35Å; N268-Y270 PolarHBondContact O-N 3.16Å; N268-L271 PolarHBondContact O-N 2.81Å; N268-H272 WeakPolarHBondContact O-CB 3.41Å; N268-H272 PolarHBondContact O-N 2.84Å
269	M	93	Very high	89.1	Confident	2 Å²	2	4.9 Å²	4.9	1%	0.01	3%	0.025	C	C	.	.	H	α-helix	trans	-64.1	-38.3	171.9	-54.7	-148.1	75.3	0	0	112.6	L118 A122 P266 H267 S273 A453 I457	L118-M269 HydrophobicContact CB-CE 3.62Å; L118-M269 HydrophobicContact CD2-CE 4.3Å; L118-M269 HydrophobicContact CG-CE 4.48Å; L118-M269 VanDerWaalsContact O-CE 3.32Å; L118-M269 WeakPolarHBondContact O-CE 3.46Å; A122-M269 WeakPolarHBondContact CB-O 3.47Å; P266-M269 WeakPolarHBondContact O-CB 3.19Å; P266-M269 PolarHBondContact O-N 3.22Å; H267-M269 PolarHBondContact O-N 3.07Å; M269-S273 WeakPolarHBondContact O-CB 3.43Å; M269-S273 PolarHBondContact O-N 2.86Å; M269-S273 PolarHBondContact O-OG 3.09Å; M269-A453 HydrophobicContact CB-CB 4.15Å; M269-A453 HydrophobicContact CG-CB 4.04Å; M269-A453 HydrophobicContact SD-CB 3.96Å; M269-I457 HydrophobicContact CB-CD1 4.35Å; M269-I457 HydrophobicContact CE-CD1 3.62Å; M269-I457 HydrophobicContact CE-CG2 3.86Å; M269-I457 HydrophobicContact SD-CG2 4.21Å
270	Y	93.9	Very high	89	Confident	1 Å²	1	9.6 Å²	9.6	0%	0.004	5%	0.047	C	C	.	.	H	α-helix	trans	-70.3	-47.3	175	-65.1	-91.4	0	0	0	110.2	L133 A134 V153 P266 H267 N268 S273 A274 V397 F401 F452 A453	L133-Y270 HydrophobicContact CB-CD1 3.72Å; L133-Y270 HydrophobicContact CB-CE1 3.97Å; L133-Y270 HydrophobicContact CB-CG 4.47Å; L133-Y270 HydrophobicContact CD2-CD1 3.8Å; L133-Y270 HydrophobicContact CD2-CD2 4.33Å; L133-Y270 HydrophobicContact CD2-CE1 3.54Å; L133-Y270 HydrophobicContact CD2-CE2 4.11Å; L133-Y270 HydrophobicContact CD2-CG 4.18Å; L133-Y270 HydrophobicContact CG-CD1 3.79Å; L133-Y270 HydrophobicContact CG-CE1 3.51Å; A134-Y270 HydrophobicContact CB-CD1 3.97Å; A134-Y270 HydrophobicContact CB-CE1 4.38Å; V153-Y270 HydrophobicContact CB-CE2 4.38Å; V153-Y270 HydrophobicContact CG1-CD2 3.81Å; V153-Y270 HydrophobicContact CG1-CE2 3.72Å; V153-Y270 HydrophobicContact CG1-CG 4.43Å; V153-Y270 HydrophobicContact CG2-CE2 3.62Å; P266-Y270 WeakPolarHBondContact O-CD2 3.47Å; H267-Y270 WeakPolarHBondContact O-CB 3.26Å; H267-Y270 PolarHBondContact O-N 3.25Å; N268-Y270 VanDerWaalsContact C-N 3.35Å; N268-Y270 PolarHBondContact O-N 3.16Å; Y270-S273 PolarHBondContact O-N 3.36Å; Y270-S273 PolarHBondContact O-OG 3.05Å; Y270-A274 PolarHBondContact O-N 3.48Å; Y270-V397 HydrophobicContact CD1-CG2 4.23Å; Y270-V397 HydrophobicContact CD2-CG2 4.5Å; Y270-V397 HydrophobicContact CG-CG2 3.97Å; Y270-F401 HydrophobicContact CD1-CE2 4.11Å; Y270-F401 AromaticContact CE1-CE2 3.55Å; Y270-F401 HydrophobicContact CE1-CE2 3.55Å; Y270-F401 AromaticContact CE1-CZ 3.71Å; Y270-F401 HydrophobicContact CE1-CZ 3.71Å; Y270-F452 PolarHBondContact OH-O 3.26Å; Y270-A453 HydrophobicContact CD2-CB 4.49Å; Y270-A453 HydrophobicContact CE2-CB 3.78Å
271	L	92.6	Very high	89.1	Confident	1 Å²	1	9.2 Å²	9.2	1%	0.005	5%	0.045	C	C	.	.	H	α-helix	trans	-52.9	-56.9	177.9	-179.9	60.7	0	0	0	112.1	H267 N268 S273 A274 L275 T389 Y392 F396	H267-L271 PolarHBondContact O-N 2.7Å; H267-L271 VanDerWaalsContact O-N 3.08Å; N268-L271 PolarHBondContact O-N 2.81Å; L271-S273 VanDerWaalsContact C-N 3.32Å; L271-S273 PolarHBondContact O-N 3.15Å; L271-A274 CarbonylContact O-C 3.56Å; L271-A274 WeakPolarHBondContact O-CA 3.32Å; L271-A274 WeakPolarHBondContact O-CB 3.43Å; L271-A274 PolarHBondContact O-N 2.65Å; L271-L275 HydrophobicContact CD1-CD1 3.97Å; L271-L275 HydrophobicContact CD1-CD2 4.25Å; L271-L275 HydrophobicContact CD1-CG 3.95Å; L271-L275 HydrophobicContact CD2-CD1 4.35Å; L271-L275 HydrophobicContact CG-CD1 3.74Å; L271-L275 HydrophobicContact CG-CG 4.14Å; L271-L275 WeakPolarHBondContact O-CG 3.11Å; L271-L275 PolarHBondContact O-N 3.01Å; L271-T389 HydrophobicContact CD2-CG2 3.88Å; L271-Y392 HydrophobicContact CD1-CG 4.47Å; L271-F396 HydrophobicContact CD1-CD2 4.17Å; L271-F396 HydrophobicContact CD1-CE2 4.14Å
272	H	94.3	Very high	89.4	Confident	0 Å²	0	12.9 Å²	12.9	0%	0	6%	0.064	C	C	.	.	H	α-helix	trans	-62.6	-38.3	-176.9	-172.1	-165.6	0	0	0	112.6	M80 Q119 A122 N268 A274 L275 V276 S300	M80-H272 HydrophobicContact CB-CB 4.09Å; M80-H272 HydrophobicContact CG-CB 3.76Å; Q119-H272 PolarHBondContact O-CE1 3.37Å; Q119-H272 PolarHBondContact O-ND1 3.01Å; Q119-H272 PolarHBondContact OE1-ND1 2.93Å; A122-H272 HydrophobicContact CB-CB 4.35Å; N268-H272 WeakPolarHBondContact O-CB 3.41Å; N268-H272 PolarHBondContact O-N 2.84Å; H272-A274 PolarHBondContact O-N 3.26Å; H272-L275 PolarHBondContact O-N 2.93Å; H272-V276 PolarHBondContact O-N 2.89Å; H272-S300 PolarHBondContact CE1-OG 2.93Å
273	S	94.7	Very high	89.5	Confident	0 Å²	0	18.8 Å²	18.8	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-63.5	-20.1	174.3	77.1	0	0	0	0	113.7	A122 G126 H132 L133 M269 Y270 L271 V276	A122-S273 WeakPolarHBondContact O-CA 3.31Å; A122-S273 WeakPolarHBondContact O-CB 3.34Å; G126-S273 WeakPolarHBondContact CA-O 3.5Å; H132-S273 WeakPolarHBondContact CB-OG 3.07Å; L133-S273 PolarHBondContact N-OG 3.06Å; M269-S273 WeakPolarHBondContact O-CB 3.43Å; M269-S273 PolarHBondContact O-N 2.86Å; M269-S273 PolarHBondContact O-OG 3.09Å; Y270-S273 PolarHBondContact O-N 3.36Å; Y270-S273 PolarHBondContact O-OG 3.05Å; L271-S273 VanDerWaalsContact C-N 3.32Å; L271-S273 PolarHBondContact O-N 3.15Å; S273-V276 WeakPolarHBondContact O-CG2 3.46Å
274	A	91.9	Very high	89.4	Confident	0 Å²	0	26 Å²	26	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-91.4	-42.4	172.5	0	0	0	0	0	112.9	F51 H132 Y270 L271 H272 V276 K277 F396	F51-A274 WeakPolarHBondContact CE2-O 3.45Å; F51-A274 WeakPolarHBondContact CZ-O 3.17Å; H132-A274 HydrophobicContact CB-CB 3.7Å; Y270-A274 PolarHBondContact O-N 3.48Å; L271-A274 CarbonylContact O-C 3.56Å; L271-A274 WeakPolarHBondContact O-CA 3.32Å; L271-A274 WeakPolarHBondContact O-CB 3.43Å; L271-A274 PolarHBondContact O-N 2.65Å; H272-A274 PolarHBondContact O-N 3.26Å; A274-V276 PolarHBondContact O-N 3.13Å; A274-K277 WeakPolarHBondContact O-CB 3.44Å; A274-K277 WeakPolarHBondContact O-CG 3.34Å; A274-K277 PolarHBondContact O-N 3.01Å; A274-F396 HydrophobicContact CB-CB 4.01Å; A274-F396 HydrophobicContact CB-CD1 3.63Å; A274-F396 HydrophobicContact CB-CD2 3.45Å; A274-F396 VanDerWaalsContact CB-CD2 3.45Å; A274-F396 HydrophobicContact CB-CE1 3.92Å; A274-F396 HydrophobicContact CB-CE2 3.73Å; A274-F396 HydrophobicContact CB-CG 3.4Å; A274-F396 HydrophobicContact CB-CZ 3.97Å
275	L	90.6	Very high	89.4	Confident	7 Å²	7	28.8 Å²	28.8	4%	0.037	14%	0.14	C	C	.	.	H	α-helix	trans	-59.4	-32.8	-178.1	-68.8	173.7	0	0	0	112.9	P76 L79 L271 H272 K277 S278	P76-L275 HydrophobicContact CB-CB 3.81Å; P76-L275 HydrophobicContact CG-CB 4.39Å; L79-L275 HydrophobicContact CB-CD1 3.57Å; L79-L275 HydrophobicContact CD2-CD1 4.28Å; L79-L275 HydrophobicContact CD2-CD2 3.83Å; L271-L275 HydrophobicContact CD1-CD1 3.97Å; L271-L275 HydrophobicContact CD1-CD2 4.25Å; L271-L275 HydrophobicContact CD1-CG 3.95Å; L271-L275 HydrophobicContact CD2-CD1 4.35Å; L271-L275 HydrophobicContact CG-CD1 3.74Å; L271-L275 HydrophobicContact CG-CG 4.14Å; L271-L275 WeakPolarHBondContact O-CG 3.11Å; L271-L275 PolarHBondContact O-N 3.01Å; H272-L275 PolarHBondContact O-N 2.93Å; L275-K277 PolarHBondContact O-N 2.91Å; L275-S278 WeakPolarHBondContact O-CB 3.28Å; L275-S278 PolarHBondContact O-N 3.43Å; L275-S278 VanDerWaalsContact O-N 3.13Å; L275-S278 PolarHBondContact O-OG 2.94Å
276	V	91.6	Very high	89.4	Confident	4 Å²	4	34.6 Å²	34.6	2%	0.024	17%	0.165	C	C	.	.	G	3₁₀ helix	trans	-64.3	-19.4	174	-64.1	0	0	0	0	113.9	A123 V127 H272 S273 A274 S278 F296	A123-V276 HydrophobicContact CB-CG1 3.99Å; V127-V276 HydrophobicContact CG2-CB 3.91Å; V127-V276 HydrophobicContact CG2-CG1 4.36Å; V127-V276 HydrophobicContact CG2-CG2 4.04Å; H272-V276 PolarHBondContact O-N 2.89Å; S273-V276 WeakPolarHBondContact O-CG2 3.46Å; A274-V276 PolarHBondContact O-N 3.13Å; V276-S278 PolarHBondContact O-N 3.14Å; V276-F296 HydrophobicContact CB-CD2 4.44Å; V276-F296 HydrophobicContact CB-CE1 4.27Å; V276-F296 HydrophobicContact CB-CE2 4Å; V276-F296 HydrophobicContact CB-CZ 3.88Å; V276-F296 HydrophobicContact CG1-CD1 3.94Å; V276-F296 HydrophobicContact CG1-CD2 4.15Å; V276-F296 HydrophobicContact CG1-CE1 3.94Å; V276-F296 HydrophobicContact CG1-CE2 4.14Å; V276-F296 HydrophobicContact CG1-CG 4.04Å; V276-F296 HydrophobicContact CG1-CZ 4.02Å
277	K	88.8	Confident	89.4	Confident	35 Å²	35	41.1 Å²	41.1	15%	0.152	20%	0.196	C	C	.	.	G	3₁₀ helix	trans	-70	-9.5	174	-59.3	168.7	68.6	177	0	113	F51 G130 H132 E135 A274 L275 R279	F51-K277 HydrophobicContact CD2-CB 4.23Å; F51-K277 HydrophobicContact CE2-CB 4.16Å; G130-K277 VanDerWaalsContact O-CE 3.26Å; G130-K277 WeakPolarHBondContact O-CE 3.07Å; H132-K277 HydrophobicContact CB-CD 4.33Å; H132-K277 PolarHBondContact CD2-NZ 3.06Å; H132-K277 VanDerWaalsContact CD2-NZ 3.28Å; E135-K277 IonicContact OE1-NZ 2.89Å; E135-K277 PolarHBondContact OE1-NZ 3.49Å; E135-K277 IonicContact OE2-NZ 2.67Å; E135-K277 PolarHBondContact OE2-NZ 3.26Å; A274-K277 WeakPolarHBondContact O-CB 3.44Å; A274-K277 WeakPolarHBondContact O-CG 3.34Å; A274-K277 PolarHBondContact O-N 3.01Å; L275-K277 PolarHBondContact O-N 2.91Å; K277-R279 VanDerWaalsContact C-N 3.32Å; K277-R279 PolarHBondContact O-N 3.02Å
278	S	85.5	Confident	89.3	Confident	2 Å²	2	44 Å²	44	1%	0.014	21%	0.209	C	C	.	.	G	3₁₀ helix	trans	-69.4	-21.9	177.8	63.4	0	0	0	0	114.8	K54 I55 L275 V276	K54-S278 WeakPolarHBondContact CA-O 3.48Å; I55-S278 PolarHBondContact N-O 3.46Å; I55-S278 VanDerWaalsContact N-O 3.09Å; L275-S278 WeakPolarHBondContact O-CB 3.28Å; L275-S278 PolarHBondContact O-N 3.43Å; L275-S278 VanDerWaalsContact O-N 3.13Å; L275-S278 PolarHBondContact O-OG 2.94Å; V276-S278 PolarHBondContact O-N 3.14Å
279	R	88	Confident	89.2	Confident	7 Å²	7	44.1 Å²	44.1	3%	0.026	21%	0.21	C	C	.	.	B	Isolated β-bridge	trans	-99.7	139.7	-179.4	-53.8	-51	-166.3	-106.9	15.7	110.1	I55 A72 F73 T74 L204 E208 K277 V281 F296	I55-R279 VanDerWaalsContact CD1-CZ 3.48Å; A72-R279 PolarHBondContact O-NE 3.31Å; F73-R279 HydrophobicContact CD1-CB 4.42Å; F73-R279 HydrophobicContact CD1-CG 4.14Å; F73-R279 HydrophobicContact CE1-CB 4.37Å; F73-R279 PolarHBondContact O-NE 3.26Å; F73-R279 VanDerWaalsContact O-NE 3.17Å; F73-R279 PolarHBondContact O-NH2 3.46Å; F73-R279 VanDerWaalsContact O-NH2 3.17Å; T74-R279 PolarHBondContact O-NH2 2.97Å; L204-R279 VanDerWaalsContact CD2-NH1 3.33Å; E208-R279 VanDerWaalsContact CD-NH2 3.33Å; E208-R279 IonicContact OE1-CZ 2.94Å; E208-R279 VanDerWaalsContact OE1-CZ 3.25Å; E208-R279 IonicContact OE1-NH1 3.1Å; E208-R279 PolarHBondContact OE1-NH1 3.18Å; E208-R279 IonicContact OE1-NH2 2.76Å; E208-R279 PolarHBondContact OE1-NH2 3Å; E208-R279 IonicContact OE2-NH2 3.15Å; E208-R279 PolarHBondContact OE2-NH2 2.83Å; E208-R279 VanDerWaalsContact OE2-NH2 3.12Å; K277-R279 VanDerWaalsContact C-N 3.32Å; K277-R279 PolarHBondContact O-N 3.02Å; R279-V281 PolarHBondContact O-N 3.27Å; R279-F296 HydrophobicContact CB-CZ 4.03Å; R279-F296 HydrophobicContact CG-CE1 4.07Å; R279-F296 HydrophobicContact CG-CZ 3.7Å
280	Q	84.3	Confident	89.1	Confident	100 Å²	100	53 Å²	53	47%	0.467	24%	0.244	S	C	.	.			trans	-74.3	121.1	174.7	-59.7	-167.3	35.3	0	0	109.7	K54 I55 I57	K54-Q280 HydrophobicContact CB-CG 3.36Å; K54-Q280 HydrophobicContact CD-CG 4.19Å; K54-Q280 HydrophobicContact CG-CG 4.41Å; K54-Q280 PolarHBondContact O-NE2 2.86Å; I55-Q280 PolarHBondContact O-N 2.69Å; I57-Q280 WeakPolarHBondContact CD1-O 3.3Å; I57-Q280 WeakPolarHBondContact CG1-O 3.35Å
281	V	86.1	Confident	89	Confident	27 Å²	27	55.2 Å²	55.2	16%	0.164	25%	0.254	C	S	.	.			trans	-136.5	125.4	177.2	-178.6	0	0	0	0	108.1	I57 F73 R279 R283 E288 V289 A292	I57-V281 HydrophobicContact CD1-CG2 4.19Å; F73-V281 HydrophobicContact CE1-CG2 4.4Å; R279-V281 PolarHBondContact O-N 3.27Å; V281-R283 PolarHBondContact O-N 3.34Å; V281-E288 HydrophobicContact CG1-CB 4.34Å; V281-V289 HydrophobicContact CG1-CG2 4.38Å; V281-A292 HydrophobicContact CG1-CB 3.98Å; V281-A292 HydrophobicContact CG2-CB 3.82Å
282	N	86.1	Confident	88.9	Confident	77 Å²	77	55.2 Å²	55.2	41%	0.412	25%	0.254	S	S	.	.			trans	-75.5	111	176.1	-171.8	-8.6	0	0	0	110.2	N284 N285 E288	N282-N284 VanDerWaalsContact C-N 3.29Å; N282-N284 PolarHBondContact O-N 3.24Å; N282-N284 WeakPolarHBondContact OD1-CB 3.44Å; N282-N284 PolarHBondContact OD1-N 3.31Å; N282-N284 VanDerWaalsContact OD1-N 3.13Å; N282-N285 HydrophobicContact CB-CB 4.32Å; N282-N285 PolarHBondContact O-N 3.43Å; N282-E288 WeakPolarHBondContact CB-OE1 3.44Å; N282-E288 WeakPolarHBondContact CB-OE2 3.43Å; N282-E288 PolarHBondContact N-OE2 2.87Å
283	R	85	Confident	88.8	Confident	124 Å²	124	56.2 Å²	56.2	47%	0.468	26%	0.259	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75.7	-19.9	-176.2	-60.6	173.9	-162	145.7	0.1	112.9	G130 V281 N285	G130-R283 VanDerWaalsContact CA-NH2 3.33Å; V281-R283 PolarHBondContact O-N 3.34Å; R283-N285 VanDerWaalsContact C-N 3.27Å
284	N	85.7	Confident	88.6	Confident	153 Å²	153	60 Å²	60	82%	0.818	28%	0.276	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.4	-27.4	175.4	-59.4	-3.3	0	0	0	110.4	N282 K286	N282-N284 VanDerWaalsContact C-N 3.29Å; N282-N284 PolarHBondContact O-N 3.24Å; N282-N284 WeakPolarHBondContact OD1-CB 3.44Å; N282-N284 PolarHBondContact OD1-N 3.31Å; N282-N284 VanDerWaalsContact OD1-N 3.13Å; N284-K286 PolarHBondContact O-N 3.31Å
285	N	88.1	Confident	88.7	Confident	62 Å²	62	60 Å²	60	33%	0.332	28%	0.276	S	S	.	.			trans	-90.3	102	176.5	-172.6	-4.4	0	0	0	111.7	N282 R283 Q287 E288 V289	N282-N285 HydrophobicContact CB-CB 4.32Å; N282-N285 PolarHBondContact O-N 3.43Å; R283-N285 VanDerWaalsContact C-N 3.27Å; N285-Q287 PolarHBondContact O-N 3.26Å; N285-Q287 VanDerWaalsContact O-N 3.09Å; N285-Q287 WeakPolarHBondContact OD1-CB 3.44Å; N285-Q287 PolarHBondContact OD1-N 3.18Å; N285-E288 HydrophobicContact CB-CB 4.19Å; N285-E288 HydrophobicContact CB-CG 4.25Å; N285-E288 VanDerWaalsContact CB-OE1 3.28Å; N285-E288 WeakPolarHBondContact CB-OE1 3.44Å; N285-E288 WeakPolarHBondContact ND2-CG 3.47Å; N285-E288 PolarHBondContact ND2-OE1 2.94Å; N285-E288 PolarHBondContact O-N 3.03Å; N285-E288 VanDerWaalsContact O-N 3.17Å; N285-V289 PolarHBondContact O-N 3Å; N285-V289 VanDerWaalsContact O-N 3.12Å
286	K	88.1	Confident	88.8	Confident	123 Å²	123	59.8 Å²	59.8	54%	0.535	27%	0.274	S	S	.	.	H	α-helix	trans	-58.5	-23.8	177.5	-59.2	-176.5	-174.1	-176.8	0	113.3	N284 R290 D469 F470	N284-K286 PolarHBondContact O-N 3.31Å; K286-R290 WeakPolarHBondContact O-CB 3.37Å; K286-R290 PolarHBondContact O-N 2.76Å; K286-R290 VanDerWaalsContact O-N 3.17Å; K286-D469 WeakPolarHBondContact CE-OD2 3.46Å; K286-D469 IonicContact NZ-OD2 3.23Å; K286-D469 PolarHBondContact NZ-OD2 3.21Å; K286-F470 HydrophobicContact CB-CZ 4.41Å
287	Q	87.6	Confident	89	Confident	138 Å²	138	62.3 Å²	62.3	65%	0.645	29%	0.285	S	S	*	.	H	α-helix	trans	-74.7	-44.8	176.8	-174.2	167.9	-49.4	0	0	111.9	N285 R290 E291	N285-Q287 PolarHBondContact O-N 3.26Å; N285-Q287 VanDerWaalsContact O-N 3.09Å; N285-Q287 WeakPolarHBondContact OD1-CB 3.44Å; N285-Q287 PolarHBondContact OD1-N 3.18Å; Q287-R290 CarbonylContact O-C 3.57Å; Q287-R290 WeakPolarHBondContact O-CB 3.37Å; Q287-R290 PolarHBondContact O-N 3.46Å; Q287-E291 WeakPolarHBondContact O-CB 3.34Å; Q287-E291 PolarHBondContact O-N 2.89Å
288	E	87.8	Confident	89.2	Confident	60 Å²	60	62.8 Å²	62.8	28%	0.28	29%	0.289	S	S	.	.	H	α-helix	trans	-63.1	-43.7	174.4	-78.7	171.7	-110.9	0	0	111.8	V281 N282 N285 R290 E291 A292	V281-E288 HydrophobicContact CG1-CB 4.34Å; N282-E288 WeakPolarHBondContact CB-OE1 3.44Å; N282-E288 WeakPolarHBondContact CB-OE2 3.43Å; N282-E288 PolarHBondContact N-OE2 2.87Å; N285-E288 HydrophobicContact CB-CB 4.19Å; N285-E288 HydrophobicContact CB-CG 4.25Å; N285-E288 VanDerWaalsContact CB-OE1 3.28Å; N285-E288 WeakPolarHBondContact CB-OE1 3.44Å; N285-E288 WeakPolarHBondContact ND2-CG 3.47Å; N285-E288 PolarHBondContact ND2-OE1 2.94Å; N285-E288 PolarHBondContact O-N 3.03Å; N285-E288 VanDerWaalsContact O-N 3.17Å; E288-R290 PolarHBondContact O-N 3.02Å; E288-E291 PolarHBondContact O-N 3.33Å; E288-E291 VanDerWaalsContact O-N 3.09Å; E288-A292 WeakPolarHBondContact O-CB 3.22Å; E288-A292 PolarHBondContact O-N 3.33Å
289	V	90.4	Very high	89.7	Confident	3 Å²	3	62.8 Å²	62.8	2%	0.018	29%	0.289	C	S	.	.	H	α-helix	trans	-58.2	-38	174.4	175.6	0	0	0	0	110.8	V127 V128 V281 N285 N293 F470	V127-V289 HydrophobicContact CG1-CG1 4.36Å; V128-V289 HydrophobicContact CG2-CG1 3.9Å; V281-V289 HydrophobicContact CG1-CG2 4.38Å; N285-V289 PolarHBondContact O-N 3Å; N285-V289 VanDerWaalsContact O-N 3.12Å; V289-N293 VanDerWaalsContact O-CB 3.31Å; V289-N293 WeakPolarHBondContact O-CB 3.32Å; V289-N293 PolarHBondContact O-N 3.46Å; V289-N293 VanDerWaalsContact O-N 3.17Å; V289-N293 PolarHBondContact O-ND2 2.87Å; V289-F470 HydrophobicContact CB-CE2 4.17Å; V289-F470 HydrophobicContact CB-CZ 3.95Å; V289-F470 HydrophobicContact CG1-CD2 4.13Å; V289-F470 HydrophobicContact CG1-CE1 4.13Å; V289-F470 HydrophobicContact CG1-CE2 3.58Å; V289-F470 HydrophobicContact CG1-CZ 3.58Å
290	R	90.5	Very high	90	Very high	190 Å²	190	62.4 Å²	62.4	72%	0.717	29%	0.287	S	S	*	.	H	α-helix	trans	-72	-35.6	175.2	-172.4	176.7	-179.8	178	-0.2	112.8	K286 Q287 E288 K294 F470	K286-R290 WeakPolarHBondContact O-CB 3.37Å; K286-R290 PolarHBondContact O-N 2.76Å; K286-R290 VanDerWaalsContact O-N 3.17Å; Q287-R290 CarbonylContact O-C 3.57Å; Q287-R290 WeakPolarHBondContact O-CB 3.37Å; Q287-R290 PolarHBondContact O-N 3.46Å; E288-R290 PolarHBondContact O-N 3.02Å; R290-K294 PolarHBondContact O-N 2.91Å; R290-F470 HydrophobicContact CB-CE1 4.36Å
291	E	90.6	Very high	90.6	Very high	46 Å²	46	59.6 Å²	59.6	22%	0.215	28%	0.278	C	S	.	.	H	α-helix	trans	-69.9	-47	177.1	-175.9	170.6	-157.6	0	0	111.5	K69 Q287 E288 N293 K294 Y295	K69-E291 WeakPolarHBondContact CD-OE1 3.41Å; K69-E291 IonicContact NZ-OE1 3.56Å; K69-E291 PolarHBondContact NZ-OE1 3.12Å; K69-E291 IonicContact NZ-OE2 2.66Å; K69-E291 PolarHBondContact NZ-OE2 3.06Å; Q287-E291 WeakPolarHBondContact O-CB 3.34Å; Q287-E291 PolarHBondContact O-N 2.89Å; E288-E291 PolarHBondContact O-N 3.33Å; E288-E291 VanDerWaalsContact O-N 3.09Å; E291-N293 PolarHBondContact O-N 3.44Å; E291-K294 WeakPolarHBondContact O-CA 3.28Å; E291-K294 VanDerWaalsContact O-CB 3.31Å; E291-K294 WeakPolarHBondContact O-CB 3.38Å; E291-K294 PolarHBondContact O-N 3.38Å; E291-Y295 HydrophobicContact CG-CD2 3.78Å; E291-Y295 HydrophobicContact CG-CE2 3.43Å; E291-Y295 VanDerWaalsContact CG-CE2 3.43Å; E291-Y295 WeakPolarHBondContact O-CD2 3.38Å; E291-Y295 PolarHBondContact O-N 3.37Å; E291-Y295 WeakPolarHBondContact OE1-CE2 3.27Å
292	A	90.9	Very high	91	Very high	1 Å²	1	62 Å²	62	1%	0.008	29%	0.289	C	S	.	.	H	α-helix	trans	-58.6	-46.1	174.2	0	0	0	0	0	111.8	F73 V127 V281 E288 K294 Y295 F296	F73-A292 HydrophobicContact CE1-CB 3.71Å; F73-A292 HydrophobicContact CZ-CB 3.7Å; V127-A292 HydrophobicContact CG1-CB 3.96Å; V281-A292 HydrophobicContact CG1-CB 3.98Å; V281-A292 HydrophobicContact CG2-CB 3.82Å; E288-A292 WeakPolarHBondContact O-CB 3.22Å; E288-A292 PolarHBondContact O-N 3.33Å; A292-K294 PolarHBondContact O-N 2.94Å; A292-Y295 PolarHBondContact O-N 3.28Å; A292-F296 HydrophobicContact CB-CD2 4.34Å; A292-F296 HydrophobicContact CB-CE2 4.3Å; A292-F296 VanDerWaalsContact O-CD2 3.25Å; A292-F296 WeakPolarHBondContact O-CD2 3.47Å; A292-F296 PolarHBondContact O-N 2.76Å
293	N	92.1	Very high	91.4	Very high	21 Å²	21	58.3 Å²	58.3	11%	0.112	27%	0.27	C	S	.	.	H	α-helix	trans	-63.2	-19.8	174.5	-81	-55	0	0	0	114	R124 V289 E291 F297	R124-N293 WeakPolarHBondContact CA-OD1 3.45Å; R124-N293 VanDerWaalsContact CG-OD1 3.28Å; R124-N293 WeakPolarHBondContact CG-OD1 3.42Å; V289-N293 VanDerWaalsContact O-CB 3.31Å; V289-N293 WeakPolarHBondContact O-CB 3.32Å; V289-N293 PolarHBondContact O-N 3.46Å; V289-N293 VanDerWaalsContact O-N 3.17Å; V289-N293 PolarHBondContact O-ND2 2.87Å; E291-N293 PolarHBondContact O-N 3.44Å; N293-F297 WeakPolarHBondContact O-CB 3.24Å
294	K	92.1	Very high	91.9	Very high	80 Å²	80	52.5 Å²	52.5	35%	0.348	25%	0.248	S	C	.	.	H	α-helix	trans	-79.3	-49.5	170.8	178.6	-174.9	175.3	-179.7	0	110.8	C64 R290 E291 A292 F297 I298	C64-K294 PolarHBondContact O-NZ 3.01Å; R290-K294 PolarHBondContact O-N 2.91Å; E291-K294 WeakPolarHBondContact O-CA 3.28Å; E291-K294 VanDerWaalsContact O-CB 3.31Å; E291-K294 WeakPolarHBondContact O-CB 3.38Å; E291-K294 PolarHBondContact O-N 3.38Å; A292-K294 PolarHBondContact O-N 2.94Å; K294-F297 PolarHBondContact O-N 3.12Å; K294-I298 HydrophobicContact CG-CD1 3.9Å; K294-I298 WeakPolarHBondContact O-CG1 3.46Å; K294-I298 PolarHBondContact O-N 3.09Å
295	Y	93	Very high	92.4	Very high	1 Å²	1	51.2 Å²	51.2	0%	0.004	24%	0.235	C	C	.	.	H	α-helix	trans	-67.4	-46.8	-177.8	-73.1	-68.4	0	0	0	113	F65 S66 K69 L70 F73 E291 A292 F297 I298 E299	F65-Y295 AromaticContact CD2-CE1 3.81Å; F65-Y295 HydrophobicContact CD2-CE1 3.81Å; F65-Y295 HydrophobicContact CE2-CD1 4.4Å; F65-Y295 AromaticContact CE2-CE1 3.89Å; F65-Y295 HydrophobicContact CE2-CE1 3.89Å; S66-Y295 PolarHBondContact N-OH 3.17Å; K69-Y295 HydrophobicContact CB-CE1 4.22Å; K69-Y295 HydrophobicContact CB-CE2 3.87Å; K69-Y295 HydrophobicContact CD-CE2 4.05Å; L70-Y295 HydrophobicContact CB-CD1 3.97Å; L70-Y295 HydrophobicContact CB-CE1 4.1Å; L70-Y295 HydrophobicContact CD1-CD1 4Å; F73-Y295 HydrophobicContact CD2-CD1 4.48Å; F73-Y295 AromaticContact CD2-CD2 3.56Å; F73-Y295 HydrophobicContact CD2-CD2 3.56Å; F73-Y295 HydrophobicContact CD2-CE2 4.45Å; F73-Y295 AromaticContact CD2-CG 3.58Å; F73-Y295 HydrophobicContact CD2-CG 3.58Å; F73-Y295 AromaticContact CE2-CD2 3.42Å; F73-Y295 HydrophobicContact CE2-CD2 3.42Å; F73-Y295 VanDerWaalsContact CE2-CD2 3.42Å; F73-Y295 HydrophobicContact CE2-CE2 4.21Å; F73-Y295 AromaticContact CE2-CG 3.94Å; F73-Y295 HydrophobicContact CE2-CG 3.94Å; F73-Y295 HydrophobicContact CG-CG 4.31Å; F73-Y295 HydrophobicContact CZ-CD2 4.36Å; E291-Y295 HydrophobicContact CG-CD2 3.78Å; E291-Y295 HydrophobicContact CG-CE2 3.43Å; E291-Y295 VanDerWaalsContact CG-CE2 3.43Å; E291-Y295 WeakPolarHBondContact O-CD2 3.38Å; E291-Y295 PolarHBondContact O-N 3.37Å; E291-Y295 WeakPolarHBondContact OE1-CE2 3.27Å; A292-Y295 PolarHBondContact O-N 3.28Å; Y295-F297 PolarHBondContact O-N 2.99Å; Y295-I298 PolarHBondContact O-N 3.38Å; Y295-I298 VanDerWaalsContact O-N 3.13Å; Y295-E299 WeakPolarHBondContact O-CB 3.38Å; Y295-E299 PolarHBondContact O-N 3.28Å
296	F	93.6	Very high	92.8	Very high	1 Å²	1	50.6 Å²	50.6	0%	0.004	23%	0.234	C	C	.	.	H	α-helix	trans	-60	-32.7	176.3	-73.7	-56.8	0	0	0	112.8	F73 P76 V127 V276 R279 A292 S300	F73-F296 HydrophobicContact CD1-CD1 4.17Å; F73-F296 HydrophobicContact CD1-CD2 4.14Å; F73-F296 AromaticContact CD1-CE1 3.77Å; F73-F296 HydrophobicContact CD1-CE1 3.77Å; F73-F296 AromaticContact CD1-CE2 3.75Å; F73-F296 HydrophobicContact CD1-CE2 3.75Å; F73-F296 HydrophobicContact CD1-CG 4.36Å; F73-F296 AromaticContact CD1-CZ 3.58Å; F73-F296 HydrophobicContact CD1-CZ 3.58Å; F73-F296 HydrophobicContact CE1-CD2 4.21Å; F73-F296 AromaticContact CE1-CE2 3.7Å; F73-F296 HydrophobicContact CE1-CE2 3.7Å; F73-F296 AromaticContact CE1-CZ 3.91Å; F73-F296 HydrophobicContact CE1-CZ 3.91Å; P76-F296 HydrophobicContact CB-CE1 4.25Å; P76-F296 HydrophobicContact CG-CE1 3.99Å; V127-F296 HydrophobicContact CG2-CD2 3.54Å; V127-F296 HydrophobicContact CG2-CE2 3.56Å; V276-F296 HydrophobicContact CB-CD2 4.44Å; V276-F296 HydrophobicContact CB-CE1 4.27Å; V276-F296 HydrophobicContact CB-CE2 4Å; V276-F296 HydrophobicContact CB-CZ 3.88Å; V276-F296 HydrophobicContact CG1-CD1 3.94Å; V276-F296 HydrophobicContact CG1-CD2 4.15Å; V276-F296 HydrophobicContact CG1-CE1 3.94Å; V276-F296 HydrophobicContact CG1-CE2 4.14Å; V276-F296 HydrophobicContact CG1-CG 4.04Å; V276-F296 HydrophobicContact CG1-CZ 4.02Å; R279-F296 HydrophobicContact CB-CZ 4.03Å; R279-F296 HydrophobicContact CG-CE1 4.07Å; R279-F296 HydrophobicContact CG-CZ 3.7Å; A292-F296 HydrophobicContact CB-CD2 4.34Å; A292-F296 HydrophobicContact CB-CE2 4.3Å; A292-F296 VanDerWaalsContact O-CD2 3.25Å; A292-F296 WeakPolarHBondContact O-CD2 3.47Å; A292-F296 PolarHBondContact O-N 2.76Å; F296-S300 VanDerWaalsContact O-CB 3.3Å; F296-S300 WeakPolarHBondContact O-CB 3.42Å; F296-S300 PolarHBondContact O-N 2.87Å; F296-S300 PolarHBondContact O-OG 3.19Å
297	F	94.4	Very high	93.1	Very high	57 Å²	57	44.8 Å²	44.8	25%	0.25	21%	0.209	C	C	.	.	H	α-helix	trans	-70.1	-46.2	173.9	178.2	-116.7	0	0	0	112	L116 R120 N293 K294 Y295 E299 S300 C301	L116-F297 HydrophobicContact CD1-CE2 4.18Å; L116-F297 HydrophobicContact CG-CE2 4.32Å; R120-F297 HydrophobicContact CB-CD2 4.1Å; R120-F297 HydrophobicContact CB-CE2 4.43Å; R120-F297 HydrophobicContact CG-CD2 3.68Å; R120-F297 HydrophobicContact CG-CE2 4.21Å; R120-F297 HydrophobicContact CG-CG 4.4Å; N293-F297 WeakPolarHBondContact O-CB 3.24Å; K294-F297 PolarHBondContact O-N 3.12Å; Y295-F297 PolarHBondContact O-N 2.99Å; F297-E299 VanDerWaalsContact C-N 3.31Å; F297-E299 PolarHBondContact O-N 3.43Å; F297-S300 PolarHBondContact O-N 3.15Å; F297-C301 VanDerWaalsContact CE2-SG 3.59Å; F297-C301 VanDerWaalsContact CZ-SG 3.55Å; F297-C301 PolarHBondContact O-N 3.09Å; F297-C301 PolarHBondContact O-SG 3.43Å
298	I	94.2	Very high	93.5	Very high	45 Å²	45	38.8 Å²	38.8	23%	0.231	18%	0.18	C	C	.	.	H	α-helix	trans	-59.9	-43.2	176.3	-69.2	168	0	0	0	110.8	F65 L70 K294 Y295 C301 I302	F65-I298 HydrophobicContact CD2-CD1 4.33Å; F65-I298 HydrophobicContact CE2-CD1 3.97Å; L70-I298 HydrophobicContact CD1-CG2 4.12Å; K294-I298 HydrophobicContact CG-CD1 3.9Å; K294-I298 WeakPolarHBondContact O-CG1 3.46Å; K294-I298 PolarHBondContact O-N 3.09Å; Y295-I298 PolarHBondContact O-N 3.38Å; Y295-I298 VanDerWaalsContact O-N 3.13Å; I298-C301 WeakPolarHBondContact O-CB 3.31Å; I298-C301 PolarHBondContact O-N 3.17Å; I298-I302 HydrophobicContact CG2-CD1 4.05Å; I298-I302 WeakPolarHBondContact O-CG1 3.42Å; I298-I302 PolarHBondContact O-N 2.97Å; I298-I302 VanDerWaalsContact O-N 3.12Å
299	E	94.3	Very high	93.9	Very high	2 Å²	2	38.6 Å²	38.6	1%	0.009	18%	0.181	C	C	.	.	H	α-helix	trans	-61	-50.6	175	-171.9	-158.3	168.7	0	0	111.8	T74 G75 G77 Y295 F297 C301 I302 A303	T74-E299 WeakPolarHBondContact CA-OE1 3.42Å; G75-E299 WeakPolarHBondContact CA-OE1 3.37Å; G75-E299 PolarHBondContact N-OE1 3.27Å; G77-E299 WeakPolarHBondContact CA-OE1 3.28Å; G77-E299 PolarHBondContact N-OE1 3.4Å; Y295-E299 WeakPolarHBondContact O-CB 3.38Å; Y295-E299 PolarHBondContact O-N 3.28Å; F297-E299 VanDerWaalsContact C-N 3.31Å; F297-E299 PolarHBondContact O-N 3.43Å; E299-C301 VanDerWaalsContact C-N 3.27Å; E299-C301 PolarHBondContact O-N 3.09Å; E299-I302 PolarHBondContact O-N 3.45Å; E299-A303 WeakPolarHBondContact O-CB 3.15Å; E299-A303 PolarHBondContact O-N 3.05Å
300	S	94.9	Very high	94.2	Very high	0 Å²	0	38.6 Å²	38.6	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-58.8	-38.4	177.9	-61	0	0	0	0	112.1	H272 F296 F297 L304	H272-S300 PolarHBondContact CE1-OG 2.93Å; F296-S300 VanDerWaalsContact O-CB 3.3Å; F296-S300 WeakPolarHBondContact O-CB 3.42Å; F296-S300 PolarHBondContact O-N 2.87Å; F296-S300 PolarHBondContact O-OG 3.19Å; F297-S300 PolarHBondContact O-N 3.15Å; S300-L304 WeakPolarHBondContact O-CB 3.49Å; S300-L304 WeakPolarHBondContact O-CG 3.32Å; S300-L304 PolarHBondContact O-N 3.44Å
301	C	96.3	Very high	94.5	Very high	41 Å²	41	29.7 Å²	29.7	28%	0.277	15%	0.147	S	C	.	.	H	α-helix	trans	-61.4	-43.5	173.9	-69	0	0	0	0	112	F297 I298 E299 F305	F297-C301 VanDerWaalsContact CE2-SG 3.59Å; F297-C301 VanDerWaalsContact CZ-SG 3.55Å; F297-C301 PolarHBondContact O-N 3.09Å; F297-C301 PolarHBondContact O-SG 3.43Å; I298-C301 WeakPolarHBondContact O-CB 3.31Å; I298-C301 PolarHBondContact O-N 3.17Å; E299-C301 VanDerWaalsContact C-N 3.27Å; E299-C301 PolarHBondContact O-N 3.09Å; C301-F305 WeakPolarHBondContact O-CB 3.43Å; C301-F305 PolarHBondContact O-N 3.42Å
302	I	95.5	Very high	94.7	Very high	76 Å²	76	27.9 Å²	27.9	39%	0.39	14%	0.139	S	C	.	.	H	α-helix	trans	-68.6	-47.6	180	-66.8	163.7	0	0	0	110.2	F78 I298 E299 F305 V306	F78-I302 HydrophobicContact CZ-CG2 4.09Å; I298-I302 HydrophobicContact CG2-CD1 4.05Å; I298-I302 WeakPolarHBondContact O-CG1 3.42Å; I298-I302 PolarHBondContact O-N 2.97Å; I298-I302 VanDerWaalsContact O-N 3.12Å; E299-I302 PolarHBondContact O-N 3.45Å; I302-F305 PolarHBondContact O-N 3.3Å; I302-V306 WeakPolarHBondContact O-CG2 3.26Å; I302-V306 PolarHBondContact O-N 3.07Å
303	A	94.7	Very high	94.9	Very high	0 Å²	0	30 Å²	30	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-62.9	-48.8	-178.1	0	0	0	0	0	112.1	G77 F78 E299 F305 V306 S307	G77-A303 VanDerWaalsContact O-CB 3.3Å; G77-A303 WeakPolarHBondContact O-CB 3.39Å; F78-A303 HydrophobicContact CD1-CB 3.99Å; F78-A303 HydrophobicContact CD2-CB 4.22Å; F78-A303 HydrophobicContact CE1-CB 4.19Å; F78-A303 HydrophobicContact CE2-CB 4.4Å; F78-A303 HydrophobicContact CG-CB 4.02Å; F78-A303 HydrophobicContact CZ-CB 4.4Å; E299-A303 WeakPolarHBondContact O-CB 3.15Å; E299-A303 PolarHBondContact O-N 3.05Å; A303-F305 VanDerWaalsContact C-N 3.33Å; A303-F305 PolarHBondContact O-N 3.41Å; A303-V306 PolarHBondContact O-N 3.17Å; A303-S307 PolarHBondContact O-N 3.06Å; A303-S307 PolarHBondContact O-OG 3.48Å
304	L	95.3	Very high	95.1	Very high	3 Å²	3	29.1 Å²	29.1	2%	0.016	14%	0.144	C	C	.	.	H	α-helix	trans	-71	-24.6	176.7	-68.4	176.7	0	0	0	113.6	M80 Y84 T112 L116 S300 F308	M80-L304 HydrophobicContact CE-CD1 3.87Å; M80-L304 HydrophobicContact CE-CD2 4.28Å; M80-L304 HydrophobicContact CE-CG 3.89Å; M80-L304 HydrophobicContact SD-CD1 4.05Å; M80-L304 HydrophobicContact SD-CD2 3.83Å; M80-L304 HydrophobicContact SD-CG 4.08Å; Y84-L304 HydrophobicContact CD1-CD2 3.75Å; Y84-L304 HydrophobicContact CD2-CD2 3.39Å; Y84-L304 HydrophobicContact CE1-CD2 3.8Å; Y84-L304 HydrophobicContact CE2-CD2 3.46Å; Y84-L304 VanDerWaalsContact CE2-CD2 3.46Å; Y84-L304 HydrophobicContact CG-CD2 3.57Å; T112-L304 HydrophobicContact CG2-CB 4.38Å; L116-L304 HydrophobicContact CB-CD1 3.76Å; L116-L304 HydrophobicContact CD1-CD1 3.98Å; L116-L304 HydrophobicContact CG-CD1 4.47Å; S300-L304 WeakPolarHBondContact O-CB 3.49Å; S300-L304 WeakPolarHBondContact O-CG 3.32Å; S300-L304 PolarHBondContact O-N 3.44Å; L304-F308 VanDerWaalsContact O-CB 3.24Å; L304-F308 WeakPolarHBondContact O-CB 3.39Å; L304-F308 PolarHBondContact O-N 2.94Å
305	F	96.3	Very high	95.2	Very high	126 Å²	126	25.3 Å²	25.3	55%	0.553	13%	0.127	S	C	*	.	H	α-helix	trans	-69.6	-40	169.7	179.6	-101.7	0	0	0	111.7	C301 I302 A303 F308 I309	C301-F305 WeakPolarHBondContact O-CB 3.43Å; C301-F305 PolarHBondContact O-N 3.42Å; I302-F305 PolarHBondContact O-N 3.3Å; A303-F305 VanDerWaalsContact C-N 3.33Å; A303-F305 PolarHBondContact O-N 3.41Å; F305-F308 PolarHBondContact O-N 3.41Å; F305-I309 HydrophobicContact CE1-CG1 4.09Å; F305-I309 HydrophobicContact CE2-CD1 4.31Å; F305-I309 HydrophobicContact CE2-CG1 4.32Å; F305-I309 HydrophobicContact CZ-CD1 4.04Å; F305-I309 HydrophobicContact CZ-CG1 3.99Å; F305-I309 WeakPolarHBondContact O-CG1 3.24Å; F305-I309 PolarHBondContact O-N 2.93Å; F305-I309 VanDerWaalsContact O-N 3.1Å
306	V	95.8	Very high	95.3	Very high	49 Å²	49	25.3 Å²	25.3	30%	0.297	13%	0.127	S	C	.	.	H	α-helix	trans	-62.4	-46.7	172.9	171.1	0	0	0	0	110.6	I215 I302 A303 I309 I310	I215-V306 HydrophobicContact CG2-CG1 4.08Å; I302-V306 WeakPolarHBondContact O-CG2 3.26Å; I302-V306 PolarHBondContact O-N 3.07Å; A303-V306 PolarHBondContact O-N 3.17Å; V306-I309 PolarHBondContact O-N 2.79Å; V306-I310 HydrophobicContact CG1-CD1 4.39Å; V306-I310 PolarHBondContact O-N 2.95Å
307	S	95.4	Very high	95.4	Very high	1 Å²	1	25.3 Å²	25.3	1%	0.007	13%	0.127	C	C	.	.	H	α-helix	trans	-58.6	-52.5	175.2	-57.2	0	0	0	0	111.1	S81 L85 A303 I309 I310 N311	S81-S307 WeakPolarHBondContact CB-OG 3.18Å; S81-S307 PolarHBondContact O-OG 2.94Å; S81-S307 PolarHBondContact OG-OG 3.04Å; L85-S307 WeakPolarHBondContact CD1-OG 3.3Å; A303-S307 PolarHBondContact O-N 3.06Å; A303-S307 PolarHBondContact O-OG 3.48Å; S307-I309 PolarHBondContact O-N 3.43Å; S307-I309 VanDerWaalsContact O-N 3.08Å; S307-I310 WeakPolarHBondContact O-CA 3.42Å; S307-I310 VanDerWaalsContact O-CB 3.31Å; S307-I310 WeakPolarHBondContact O-CB 3.36Å; S307-I310 PolarHBondContact O-N 3.24Å; S307-N311 VanDerWaalsContact C-OD1 3.26Å; S307-N311 PolarHBondContact O-N 3.42Å; S307-N311 PolarHBondContact O-OD1 2.95Å
308	F	96.1	Very high	95.3	Very high	12 Å²	12	22.6 Å²	22.6	5%	0.053	12%	0.116	C	C	.	.	H	α-helix	trans	-50.6	-39.5	177.7	176.5	-111.1	0	0	0	114.2	L108 L109 T112 M240 L304 F305 I310 N311 V312	L108-F308 HydrophobicContact CD2-CD2 4.48Å; L108-F308 HydrophobicContact CD2-CE2 4.23Å; L108-F308 HydrophobicContact CG-CD2 4.16Å; L108-F308 HydrophobicContact CG-CE2 3.97Å; L109-F308 HydrophobicContact CB-CE2 3.78Å; L109-F308 HydrophobicContact CB-CZ 3.79Å; L109-F308 HydrophobicContact CD1-CE1 3.96Å; L109-F308 HydrophobicContact CD1-CE2 4.03Å; L109-F308 HydrophobicContact CD1-CZ 3.63Å; L109-F308 HydrophobicContact CG-CZ 4.2Å; T112-F308 HydrophobicContact CG2-CB 4.1Å; M240-F308 HydrophobicContact CE-CE1 3.8Å; M240-F308 HydrophobicContact CE-CZ 3.87Å; L304-F308 VanDerWaalsContact O-CB 3.24Å; L304-F308 WeakPolarHBondContact O-CB 3.39Å; L304-F308 PolarHBondContact O-N 2.94Å; F305-F308 PolarHBondContact O-N 3.41Å; F308-I310 VanDerWaalsContact C-N 3.35Å; F308-N311 PolarHBondContact O-N 3.24Å; F308-V312 HydrophobicContact CD1-CG2 4.32Å; F308-V312 HydrophobicContact CD2-CG2 4.11Å; F308-V312 HydrophobicContact CE1-CG2 3.85Å; F308-V312 HydrophobicContact CE2-CG2 3.58Å; F308-V312 HydrophobicContact CG-CG2 4.44Å; F308-V312 HydrophobicContact CZ-CG2 3.44Å; F308-V312 VanDerWaalsContact CZ-CG2 3.44Å; F308-V312 WeakPolarHBondContact O-CB 3.47Å; F308-V312 VanDerWaalsContact O-CG2 3.25Å; F308-V312 WeakPolarHBondContact O-CG2 3.21Å; F308-V312 PolarHBondContact O-N 3.39Å
309	I	96.2	Very high	95.2	Very high	55 Å²	55	20.7 Å²	20.7	28%	0.282	11%	0.106	S	C	.	.	H	α-helix	trans	-65.8	-37.5	176.6	-68.8	-66.4	0	0	0	111.6	F305 V306 S307 F313	F305-I309 HydrophobicContact CE1-CG1 4.09Å; F305-I309 HydrophobicContact CE2-CD1 4.31Å; F305-I309 HydrophobicContact CE2-CG1 4.32Å; F305-I309 HydrophobicContact CZ-CD1 4.04Å; F305-I309 HydrophobicContact CZ-CG1 3.99Å; F305-I309 WeakPolarHBondContact O-CG1 3.24Å; F305-I309 PolarHBondContact O-N 2.93Å; F305-I309 VanDerWaalsContact O-N 3.1Å; V306-I309 PolarHBondContact O-N 2.79Å; S307-I309 PolarHBondContact O-N 3.43Å; S307-I309 VanDerWaalsContact O-N 3.08Å; I309-F313 HydrophobicContact CG2-CD2 4.4Å; I309-F313 HydrophobicContact CG2-CE1 3.89Å; I309-F313 HydrophobicContact CG2-CE2 3.76Å; I309-F313 HydrophobicContact CG2-CZ 3.47Å; I309-F313 VanDerWaalsContact CG2-CZ 3.47Å; I309-F313 WeakPolarHBondContact O-CD1 3.27Å; I309-F313 WeakPolarHBondContact O-CG 3.36Å; I309-F313 PolarHBondContact O-N 2.92Å
310	I	96.3	Very high	95	Very high	3 Å²	3	24.2 Å²	24.2	2%	0.015	12%	0.123	C	C	.	.	H	α-helix	trans	-66	-47.6	174.1	-62	166.9	0	0	0	110.7	L85 I215 M218 A219 F222 V306 S307 F308 V312 F313 V314	L85-I310 HydrophobicContact CD1-CD1 3.81Å; L85-I310 HydrophobicContact CD2-CB 3.74Å; L85-I310 HydrophobicContact CD2-CD1 3.96Å; L85-I310 HydrophobicContact CD2-CG1 4.45Å; L85-I310 HydrophobicContact CD2-CG2 3.71Å; I215-I310 HydrophobicContact CG2-CD1 4.46Å; M218-I310 HydrophobicContact CB-CD1 4.4Å; A219-I310 HydrophobicContact CB-CD1 4.04Å; A219-I310 HydrophobicContact CB-CG1 4.24Å; F222-I310 HydrophobicContact CB-CG2 4.26Å; F222-I310 HydrophobicContact CD2-CG2 3.53Å; F222-I310 HydrophobicContact CE2-CG2 4.32Å; F222-I310 HydrophobicContact CG-CG2 4.3Å; V306-I310 HydrophobicContact CG1-CD1 4.39Å; V306-I310 PolarHBondContact O-N 2.95Å; S307-I310 WeakPolarHBondContact O-CA 3.42Å; S307-I310 VanDerWaalsContact O-CB 3.31Å; S307-I310 WeakPolarHBondContact O-CB 3.36Å; S307-I310 PolarHBondContact O-N 3.24Å; F308-I310 VanDerWaalsContact C-N 3.35Å; I310-V312 VanDerWaalsContact C-N 3.34Å; I310-V312 PolarHBondContact O-N 3.05Å; I310-F313 WeakPolarHBondContact O-CA 3.49Å; I310-F313 WeakPolarHBondContact O-CB 3.29Å; I310-F313 PolarHBondContact O-N 3.4Å; I310-V314 PolarHBondContact O-N 3.02Å
311	N	95.9	Very high	94.6	Very high	4 Å²	4	24.6 Å²	24.6	2%	0.021	13%	0.126	C	C	.	.	H	α-helix	trans	-55.9	-46.6	174.7	-68.7	73.2	0	0	0	111.5	Y84 L85 N89 D93 L108 S307 F308 F313 V314 V315	Y84-N311 PolarHBondContact O-ND2 3.41Å; Y84-N311 PolarHBondContact O-OD1 3.47Å; L85-N311 WeakPolarHBondContact CD2-OD1 3.46Å; N89-N311 PolarHBondContact OD1-ND2 3.03Å; D93-N311 WeakPolarHBondContact OD2-CA 3.24Å; D93-N311 WeakPolarHBondContact OD2-CB 3.4Å; D93-N311 VanDerWaalsContact OD2-CG 3.25Å; D93-N311 PolarHBondContact OD2-ND2 3.3Å; L108-N311 HydrophobicContact CD1-CB 4.04Å; L108-N311 HydrophobicContact CD2-CB 3.76Å; L108-N311 HydrophobicContact CG-CB 4.41Å; S307-N311 VanDerWaalsContact C-OD1 3.26Å; S307-N311 PolarHBondContact O-N 3.42Å; S307-N311 PolarHBondContact O-OD1 2.95Å; F308-N311 PolarHBondContact O-N 3.24Å; N311-F313 VanDerWaalsContact C-N 3.3Å; N311-F313 PolarHBondContact O-N 3.31Å; N311-V314 PolarHBondContact O-N 3Å; N311-V314 VanDerWaalsContact O-N 3.17Å; N311-V315 WeakPolarHBondContact O-CG2 3.42Å; N311-V315 PolarHBondContact O-N 3.12Å
312	V	95.9	Very high	94.1	Very high	7 Å²	7	23 Å²	23	4%	0.042	11%	0.114	C	C	.	.	H	α-helix	trans	-60.6	-36.5	174.1	169.5	0	0	0	0	112.1	L105 L108 V236 M240 F308 I310 S316	L105-V312 HydrophobicContact CD2-CG1 4.48Å; L105-V312 HydrophobicContact CD2-CG2 4.23Å; L108-V312 HydrophobicContact CD2-CG2 4.11Å; V236-V312 HydrophobicContact CG1-CG1 4.02Å; M240-V312 HydrophobicContact SD-CG1 4.32Å; F308-V312 HydrophobicContact CD1-CG2 4.32Å; F308-V312 HydrophobicContact CD2-CG2 4.11Å; F308-V312 HydrophobicContact CE1-CG2 3.85Å; F308-V312 HydrophobicContact CE2-CG2 3.58Å; F308-V312 HydrophobicContact CG-CG2 4.44Å; F308-V312 HydrophobicContact CZ-CG2 3.44Å; F308-V312 VanDerWaalsContact CZ-CG2 3.44Å; F308-V312 WeakPolarHBondContact O-CB 3.47Å; F308-V312 VanDerWaalsContact O-CG2 3.25Å; F308-V312 WeakPolarHBondContact O-CG2 3.21Å; F308-V312 PolarHBondContact O-N 3.39Å; I310-V312 VanDerWaalsContact C-N 3.34Å; I310-V312 PolarHBondContact O-N 3.05Å; V312-S316 WeakPolarHBondContact O-CB 3.34Å; V312-S316 PolarHBondContact O-N 3.41Å; V312-S316 PolarHBondContact O-OG 3.26Å
313	F	95.8	Very high	93.5	Very high	45 Å²	45	24.3 Å²	24.3	20%	0.197	12%	0.117	C	C	.	.	H	α-helix	trans	-62.6	-48.2	173.2	-65.3	-23	0	0	0	111.5	F222 Y226 I309 I310 N311 S316 V317	F222-F313 HydrophobicContact CB-CB 4.45Å; Y226-F313 AromaticContact CD1-CD1 3.85Å; Y226-F313 HydrophobicContact CD1-CD1 3.85Å; Y226-F313 AromaticContact CD1-CE1 3.91Å; Y226-F313 HydrophobicContact CD1-CE1 3.91Å; Y226-F313 HydrophobicContact CD2-CB 4.15Å; Y226-F313 AromaticContact CD2-CD1 3.58Å; Y226-F313 HydrophobicContact CD2-CD1 3.58Å; Y226-F313 HydrophobicContact CD2-CE1 4.42Å; Y226-F313 HydrophobicContact CD2-CG 4.22Å; Y226-F313 HydrophobicContact CE1-CD1 4.2Å; Y226-F313 HydrophobicContact CE1-CE1 4.11Å; Y226-F313 AromaticContact CE2-CD1 3.92Å; Y226-F313 HydrophobicContact CE2-CD1 3.92Å; Y226-F313 HydrophobicContact CG-CB 4.33Å; Y226-F313 AromaticContact CG-CD1 3.52Å; Y226-F313 HydrophobicContact CG-CD1 3.52Å; Y226-F313 HydrophobicContact CG-CE1 4.07Å; Y226-F313 HydrophobicContact CG-CG 4.11Å; I309-F313 HydrophobicContact CG2-CD2 4.4Å; I309-F313 HydrophobicContact CG2-CE1 3.89Å; I309-F313 HydrophobicContact CG2-CE2 3.76Å; I309-F313 HydrophobicContact CG2-CZ 3.47Å; I309-F313 VanDerWaalsContact CG2-CZ 3.47Å; I309-F313 WeakPolarHBondContact O-CD1 3.27Å; I309-F313 WeakPolarHBondContact O-CG 3.36Å; I309-F313 PolarHBondContact O-N 2.92Å; I310-F313 WeakPolarHBondContact O-CA 3.49Å; I310-F313 WeakPolarHBondContact O-CB 3.29Å; I310-F313 PolarHBondContact O-N 3.4Å; N311-F313 VanDerWaalsContact C-N 3.3Å; N311-F313 PolarHBondContact O-N 3.31Å; F313-S316 PolarHBondContact O-N 3Å; F313-V317 WeakPolarHBondContact O-CB 3.5Å; F313-V317 VanDerWaalsContact O-CG2 3.29Å; F313-V317 WeakPolarHBondContact O-CG2 3.46Å; F313-V317 PolarHBondContact O-N 3.4Å
314	V	95.2	Very high	92.9	Very high	3 Å²	3	27.2 Å²	27.2	2%	0.018	15%	0.147	C	C	.	.	H	α-helix	trans	-58.8	-60.5	177.2	176.7	0	0	0	0	110.5	I90 D93 L94 F222 I310 N311 S316 V317 F318 W375	I90-V314 HydrophobicContact CG2-CG1 4.21Å; I90-V314 HydrophobicContact CG2-CG2 4.46Å; D93-V314 HydrophobicContact CB-CB 4.38Å; D93-V314 HydrophobicContact CB-CG1 3.95Å; L94-V314 HydrophobicContact CB-CG1 3.99Å; F222-V314 HydrophobicContact CB-CG2 4.36Å; F222-V314 HydrophobicContact CD1-CG2 4.29Å; F222-V314 HydrophobicContact CD2-CG2 4.47Å; F222-V314 HydrophobicContact CG-CG2 4.13Å; I310-V314 PolarHBondContact O-N 3.02Å; N311-V314 PolarHBondContact O-N 3Å; N311-V314 VanDerWaalsContact O-N 3.17Å; V314-S316 PolarHBondContact O-N 2.96Å; V314-S316 VanDerWaalsContact O-N 3.11Å; V314-V317 PolarHBondContact O-N 2.92Å; V314-V317 VanDerWaalsContact O-N 3.09Å; V314-F318 HydrophobicContact CG1-CD2 4.01Å; V314-F318 HydrophobicContact CG1-CE2 4.25Å; V314-F318 WeakPolarHBondContact O-CD2 3.37Å; V314-F318 PolarHBondContact O-N 3.24Å; V314-F318 VanDerWaalsContact O-N 3.08Å; V314-W375 HydrophobicContact CG1-CH2 4.43Å
315	V	95.1	Very high	92.4	Very high	1 Å²	1	30.4 Å²	30.4	1%	0.006	16%	0.161	C	C	.	.	H	α-helix	trans	-52.9	-41.1	-178.5	178.8	0	0	0	0	111.5	D93 L105 L108 N311 A319	D93-V315 HydrophobicContact CB-CG2 3.57Å; D93-V315 VanDerWaalsContact CG-CG2 3.47Å; D93-V315 WeakPolarHBondContact OD1-CG2 3.5Å; L105-V315 HydrophobicContact CD2-CB 3.77Å; L105-V315 HydrophobicContact CD2-CG1 3.58Å; L105-V315 HydrophobicContact CD2-CG2 4.38Å; L105-V315 HydrophobicContact CG-CG1 4.05Å; L108-V315 HydrophobicContact CD2-CG2 3.94Å; N311-V315 WeakPolarHBondContact O-CG2 3.42Å; N311-V315 PolarHBondContact O-N 3.12Å; V315-A319 WeakPolarHBondContact O-CB 3.21Å; V315-A319 PolarHBondContact O-N 2.98Å
316	S	94.9	Very high	91.9	Very high	0 Å²	0	25.5 Å²	25.5	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-72.7	-36.5	-178.3	-57.4	0	0	0	0	113.9	V312 F313 V314 E320	V312-S316 WeakPolarHBondContact O-CB 3.34Å; V312-S316 PolarHBondContact O-N 3.41Å; V312-S316 PolarHBondContact O-OG 3.26Å; F313-S316 PolarHBondContact O-N 3Å; V314-S316 PolarHBondContact O-N 2.96Å; V314-S316 VanDerWaalsContact O-N 3.11Å; S316-E320 PolarHBondContact O-N 3.43Å; S316-E320 VanDerWaalsContact O-N 3.14Å
317	V	94.5	Very high	91.4	Very high	2 Å²	2	23.5 Å²	23.5	1%	0.012	13%	0.129	C	C	.	.	H	α-helix	trans	-62	-49.7	174.3	158.2	0	0	0	0	110.2	E225 V229 F313 V314 E320 A321 L363	E225-V317 HydrophobicContact CB-CG1 4.41Å; E225-V317 HydrophobicContact CB-CG2 3.91Å; V229-V317 HydrophobicContact CB-CG2 4.38Å; V229-V317 HydrophobicContact CG2-CG1 4.18Å; V229-V317 HydrophobicContact CG2-CG2 4.3Å; F313-V317 WeakPolarHBondContact O-CB 3.5Å; F313-V317 VanDerWaalsContact O-CG2 3.29Å; F313-V317 WeakPolarHBondContact O-CG2 3.46Å; F313-V317 PolarHBondContact O-N 3.4Å; V314-V317 PolarHBondContact O-N 2.92Å; V314-V317 VanDerWaalsContact O-N 3.09Å; V317-E320 PolarHBondContact O-N 2.96Å; V317-A321 WeakPolarHBondContact O-CB 3.29Å; V317-A321 PolarHBondContact O-N 2.99Å; V317-L363 HydrophobicContact CG1-CD1 4.43Å; V317-L363 HydrophobicContact CG1-CD2 3.83Å
318	F	92.6	Very high	90.8	Very high	0 Å²	0	28.3 Å²	28.3	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-73.2	-31.3	-178.3	-73.6	-91.1	0	0	0	112.4	L94 V314 F322 V354 L363 W375	L94-F318 HydrophobicContact CB-CB 4.24Å; L94-F318 HydrophobicContact CB-CD1 3.88Å; L94-F318 HydrophobicContact CB-CD2 3.64Å; L94-F318 HydrophobicContact CB-CE1 4.19Å; L94-F318 HydrophobicContact CB-CE2 3.97Å; L94-F318 HydrophobicContact CB-CG 3.62Å; L94-F318 HydrophobicContact CB-CZ 4.24Å; L94-F318 HydrophobicContact CD1-CD1 4.23Å; L94-F318 HydrophobicContact CD1-CE1 4.34Å; L94-F318 WeakPolarHBondContact O-CB 3.35Å; V314-F318 HydrophobicContact CG1-CD2 4.01Å; V314-F318 HydrophobicContact CG1-CE2 4.25Å; V314-F318 WeakPolarHBondContact O-CD2 3.37Å; V314-F318 PolarHBondContact O-N 3.24Å; V314-F318 VanDerWaalsContact O-N 3.08Å; F318-F322 HydrophobicContact CB-CD2 4.22Å; F318-F322 AromaticContact CD1-CD2 3.51Å; F318-F322 HydrophobicContact CD1-CD2 3.51Å; F318-F322 HydrophobicContact CD1-CE1 4.5Å; F318-F322 AromaticContact CD1-CE2 3.15Å; F318-F322 HydrophobicContact CD1-CE2 3.15Å; F318-F322 HydrophobicContact CD1-CG 4.35Å; F318-F322 AromaticContact CD1-CZ 3.7Å; F318-F322 HydrophobicContact CD1-CZ 3.7Å; F318-F322 HydrophobicContact CE1-CD2 4.23Å; F318-F322 AromaticContact CE1-CE2 3.4Å; F318-F322 HydrophobicContact CE1-CE2 3.4Å; F318-F322 AromaticContact CE1-CZ 3.6Å; F318-F322 HydrophobicContact CE1-CZ 3.6Å; F318-F322 HydrophobicContact CG-CD2 4.23Å; F318-F322 HydrophobicContact CG-CE2 4.12Å; F318-F322 WeakPolarHBondContact O-CB 3.37Å; F318-F322 WeakPolarHBondContact O-CD2 3.36Å; F318-F322 PolarHBondContact O-N 2.74Å; F318-V354 HydrophobicContact CD1-CG1 4.24Å; F318-V354 HydrophobicContact CE1-CG1 4.38Å; F318-L363 HydrophobicContact CE2-CD1 4.38Å; F318-L363 HydrophobicContact CZ-CD1 3.88Å; F318-L363 HydrophobicContact CZ-CG 4.49Å; F318-W375 HydrophobicContact CE2-CE3 4.14Å; F318-W375 AromaticContact CE2-CH2 3.44Å; F318-W375 HydrophobicContact CE2-CH2 3.44Å; F318-W375 VanDerWaalsContact CE2-CH2 3.44Å; F318-W375 HydrophobicContact CE2-CZ2 4.14Å; F318-W375 AromaticContact CE2-CZ3 3.45Å; F318-W375 HydrophobicContact CE2-CZ3 3.45Å; F318-W375 VanDerWaalsContact CE2-CZ3 3.45Å; F318-W375 HydrophobicContact CZ-CD2 4.42Å; F318-W375 HydrophobicContact CZ-CE3 4.2Å; F318-W375 AromaticContact CZ-CH2 3.57Å; F318-W375 HydrophobicContact CZ-CH2 3.57Å; F318-W375 AromaticContact CZ-CZ2 3.77Å; F318-W375 HydrophobicContact CZ-CZ2 3.77Å; F318-W375 AromaticContact CZ-CZ3 3.81Å; F318-W375 HydrophobicContact CZ-CZ3 3.81Å
319	A	92.2	Very high	90.2	Very high	4 Å²	4	31.8 Å²	31.8	3%	0.033	17%	0.168	C	C	.	.	H	α-helix	trans	-60.8	-45.7	170.8	0	0	0	0	0	113.3	G97 F102 V315 F323	G97-A319 WeakPolarHBondContact O-CA 3.33Å; F102-A319 HydrophobicContact CD1-CB 3.93Å; F102-A319 HydrophobicContact CE1-CB 3.69Å; F102-A319 HydrophobicContact CE2-CB 4.32Å; F102-A319 HydrophobicContact CG-CB 4.34Å; F102-A319 HydrophobicContact CZ-CB 3.9Å; V315-A319 WeakPolarHBondContact O-CB 3.21Å; V315-A319 PolarHBondContact O-N 2.98Å; A319-F323 WeakPolarHBondContact O-CB 3.41Å; A319-F323 PolarHBondContact O-N 3.34Å
320	E	91.1	Very high	89.6	Confident	77 Å²	77	29.2 Å²	29.2	36%	0.36	16%	0.155	S	C	.	.	H	α-helix	trans	-77.1	-34.4	-179.1	-163.1	77.6	-124.6	0	0	112	F102 V229 P231 S232 S316 V317	F102-E320 HydrophobicContact CZ-CB 4.3Å; V229-E320 HydrophobicContact CG1-CB 3.98Å; V229-E320 HydrophobicContact CG1-CG 4.31Å; P231-E320 VanDerWaalsContact CA-OE2 3.32Å; P231-E320 WeakPolarHBondContact CA-OE2 3.19Å; P231-E320 HydrophobicContact CB-CB 3.95Å; P231-E320 HydrophobicContact CB-CG 4.32Å; S232-E320 PolarHBondContact N-OE2 3.4Å; S232-E320 PolarHBondContact OG-OE2 3.42Å; S232-E320 VanDerWaalsContact OG-OE2 3.09Å; S316-E320 PolarHBondContact O-N 3.43Å; S316-E320 VanDerWaalsContact O-N 3.14Å; V317-E320 PolarHBondContact O-N 2.96Å
321	A	86.5	Confident	89.1	Confident	7 Å²	7	29.6 Å²	29.6	6%	0.058	16%	0.157	C	C	.	.	H	α-helix	trans	-80.4	-37.3	-177.8	0	0	0	0	0	114.5	V317 K325 F367	V317-A321 WeakPolarHBondContact O-CB 3.29Å; V317-A321 PolarHBondContact O-N 2.99Å; A321-K325 VanDerWaalsContact O-CE 3.31Å; A321-K325 WeakPolarHBondContact O-CE 3.24Å; A321-K325 WeakPolarHBondContact O-CG 3.34Å; A321-F367 HydrophobicContact CB-CE2 4.2Å
322	F	85	Confident	88.6	Confident	9 Å²	9	35.3 Å²	35.3	4%	0.039	18%	0.184	C	C	.	.	H	α-helix	trans	-112.9	-24.2	-168.5	-63.1	-109.3	0	0	0	114.9	A98 F318 G324 K325 L352 V354 V362	A98-F322 HydrophobicContact CB-CB 3.92Å; F318-F322 HydrophobicContact CB-CD2 4.22Å; F318-F322 AromaticContact CD1-CD2 3.51Å; F318-F322 HydrophobicContact CD1-CD2 3.51Å; F318-F322 HydrophobicContact CD1-CE1 4.5Å; F318-F322 AromaticContact CD1-CE2 3.15Å; F318-F322 HydrophobicContact CD1-CE2 3.15Å; F318-F322 HydrophobicContact CD1-CG 4.35Å; F318-F322 AromaticContact CD1-CZ 3.7Å; F318-F322 HydrophobicContact CD1-CZ 3.7Å; F318-F322 HydrophobicContact CE1-CD2 4.23Å; F318-F322 AromaticContact CE1-CE2 3.4Å; F318-F322 HydrophobicContact CE1-CE2 3.4Å; F318-F322 AromaticContact CE1-CZ 3.6Å; F318-F322 HydrophobicContact CE1-CZ 3.6Å; F318-F322 HydrophobicContact CG-CD2 4.23Å; F318-F322 HydrophobicContact CG-CE2 4.12Å; F318-F322 WeakPolarHBondContact O-CB 3.37Å; F318-F322 WeakPolarHBondContact O-CD2 3.36Å; F318-F322 PolarHBondContact O-N 2.74Å; F322-G324 PolarHBondContact O-N 2.98Å; F322-K325 WeakPolarHBondContact O-CG 3.25Å; F322-K325 PolarHBondContact O-N 3.41Å; F322-L352 HydrophobicContact CD1-CD2 3.78Å; F322-L352 HydrophobicContact CE1-CD2 3.92Å; F322-V354 HydrophobicContact CB-CG2 4.35Å; F322-V354 HydrophobicContact CD1-CB 4.33Å; F322-V354 HydrophobicContact CD1-CG1 3.81Å; F322-V354 HydrophobicContact CD1-CG2 3.45Å; F322-V354 VanDerWaalsContact CD1-CG2 3.45Å; F322-V354 HydrophobicContact CE1-CB 4.45Å; F322-V354 HydrophobicContact CE1-CG1 3.52Å; F322-V354 HydrophobicContact CE1-CG2 4Å; F322-V354 HydrophobicContact CG-CG2 4.13Å; F322-V354 HydrophobicContact CZ-CG1 4.04Å; F322-V362 HydrophobicContact CD1-CG1 4.38Å; F322-V362 HydrophobicContact CE1-CB 3.64Å; F322-V362 HydrophobicContact CE1-CG1 3.69Å; F322-V362 HydrophobicContact CE1-CG2 3.71Å; F322-V362 HydrophobicContact CE2-CB 4.4Å; F322-V362 HydrophobicContact CE2-CG1 4.07Å; F322-V362 HydrophobicContact CZ-CB 3.46Å; F322-V362 VanDerWaalsContact CZ-CB 3.46Å; F322-V362 HydrophobicContact CZ-CG1 3.52Å; F322-V362 HydrophobicContact CZ-CG2 4.06Å
323	F	83.9	Confident	88.1	Confident	102 Å²	102	36.9 Å²	36.9	45%	0.447	19%	0.193	S	C	.	.	T	Hydrogen-bonded Turn	trans	-62.1	114.9	-171.9	-175.1	-104.8	0	0	0	111.7	A100 G101 A319	A100-F323 VanDerWaalsContact C-CE2 3.49Å; G101-F323 VanDerWaalsContact N-CD2 3.3Å; A319-F323 WeakPolarHBondContact O-CB 3.41Å; A319-F323 PolarHBondContact O-N 3.34Å
324	G	82	Confident	87.6	Confident	62 Å²	62	34.7 Å²	34.7	64%	0.639	18%	0.184	S	C	*	.	T	Hydrogen-bonded Turn	trans	79.3	15	-178.8	0	0	0	0	0	116	F322	F322-G324 PolarHBondContact O-N 2.98Å
325	K	84.9	Confident	87.1	Confident	69 Å²	69	38.2 Å²	38.2	30%	0.3	21%	0.205	S	C	.	.			trans	-84.3	148	171.1	-53.4	-58.5	179.2	-178.3	0	111.9	A321 F322 V330	A321-K325 VanDerWaalsContact O-CE 3.31Å; A321-K325 WeakPolarHBondContact O-CE 3.24Å; A321-K325 WeakPolarHBondContact O-CG 3.34Å; F322-K325 WeakPolarHBondContact O-CG 3.25Å; F322-K325 PolarHBondContact O-N 3.41Å; K325-V330 HydrophobicContact CB-CG2 4.37Å
326	T	85.6	Confident	86.7	Confident	24 Å²	24	43.8 Å²	43.8	15%	0.147	24%	0.235	C	C	.	.	B	Isolated β-bridge	trans	-102	159.4	168.2	59.2	0	0	0	0	111	E328 Q329 V330 S350	T326-E328 VanDerWaalsContact C-N 3.29Å; T326-E328 PolarHBondContact O-N 2.94Å; T326-Q329 PolarHBondContact O-N 2.99Å; T326-Q329 WeakPolarHBondContact OG1-CG 3.42Å; T326-V330 PolarHBondContact O-N 2.77Å; T326-S350 WeakPolarHBondContact CA-O 3.45Å
327	N	83.8	Confident	86	Confident	6 Å²	6	47 Å²	47	3%	0.032	26%	0.255	C	S	.	.	H	α-helix	trans	-59.4	-40.5	179	-60.9	-63.4	0	0	0	112.1	Q329 V330 V331 P346 D348 S350 L352	N327-Q329 VanDerWaalsContact C-N 3.35Å; N327-Q329 PolarHBondContact O-N 3.32Å; N327-V330 PolarHBondContact O-N 2.76Å; N327-V330 VanDerWaalsContact O-N 3.1Å; N327-V331 WeakPolarHBondContact O-CG2 3.46Å; N327-V331 PolarHBondContact O-N 3.21Å; N327-P346 WeakPolarHBondContact CB-O 3.48Å; N327-D348 WeakPolarHBondContact CB-O 3.34Å; N327-S350 PolarHBondContact N-O 2.84Å; N327-S350 PolarHBondContact ND2-O 2.95Å; N327-S350 PolarHBondContact ND2-OG 3.38Å; N327-L352 WeakPolarHBondContact OD1-CA 3.31Å; N327-L352 WeakPolarHBondContact OD1-CB 3.46Å; N327-L352 WeakPolarHBondContact OD1-CD1 3.49Å
328	E	82.7	Confident	85.2	Confident	102 Å²	102	51.9 Å²	51.9	48%	0.477	29%	0.289	S	S	.	.	H	α-helix	trans	-54.3	-45.1	177.4	-174.5	169.6	-149.8	0	0	113.2	T326 V330 V331 E332 D348 N349	T326-E328 VanDerWaalsContact C-N 3.29Å; T326-E328 PolarHBondContact O-N 2.94Å; E328-V330 VanDerWaalsContact C-N 3.32Å; E328-V330 PolarHBondContact O-N 2.81Å; E328-V331 PolarHBondContact O-N 2.95Å; E328-E332 PolarHBondContact O-N 3.4Å; E328-D348 PolarHBondContact N-O 3.1Å; E328-N349 PolarHBondContact OE2-ND2 3.49Å
329	Q	84	Confident	84.4	Confident	86 Å²	86	53 Å²	53	40%	0.402	30%	0.297	S	S	.	.	H	α-helix	trans	-63.4	-37.4	177.5	-67.8	173	1.8	0	0	112.5	T326 N327 V333	T326-Q329 PolarHBondContact O-N 2.99Å; T326-Q329 WeakPolarHBondContact OG1-CG 3.42Å; N327-Q329 VanDerWaalsContact C-N 3.35Å; N327-Q329 PolarHBondContact O-N 3.32Å; Q329-V333 WeakPolarHBondContact O-CG2 3.48Å; Q329-V333 PolarHBondContact O-N 3.45Å
330	V	84.6	Confident	83.3	Confident	1 Å²	1	58 Å²	58	1%	0.006	33%	0.329	C	S	.	.	H	α-helix	trans	-73	-40.6	179.4	174.2	0	0	0	0	110.7	K325 T326 N327 E328 E332 V333 C334 F345 L352 V362 Y366	K325-V330 HydrophobicContact CB-CG2 4.37Å; T326-V330 PolarHBondContact O-N 2.77Å; N327-V330 PolarHBondContact O-N 2.76Å; N327-V330 VanDerWaalsContact O-N 3.1Å; E328-V330 VanDerWaalsContact C-N 3.32Å; E328-V330 PolarHBondContact O-N 2.81Å; V330-E332 VanDerWaalsContact C-N 3.35Å; V330-E332 PolarHBondContact O-N 3.17Å; V330-V333 PolarHBondContact O-N 3.12Å; V330-C334 WeakPolarHBondContact O-CB 3.44Å; V330-C334 PolarHBondContact O-N 3.17Å; V330-C334 PolarHBondContact O-SG 2.84Å; V330-C334 VanDerWaalsContact O-SG 3.38Å; V330-F345 HydrophobicContact CG1-CD2 3.91Å; V330-F345 HydrophobicContact CG1-CE1 4.5Å; V330-F345 HydrophobicContact CG1-CE2 3.85Å; V330-F345 HydrophobicContact CG1-CG 4.29Å; V330-F345 HydrophobicContact CG1-CZ 4.16Å; V330-L352 HydrophobicContact CG1-CD2 4.42Å; V330-L352 HydrophobicContact CG2-CD2 4.04Å; V330-V362 HydrophobicContact CG1-CG2 3.57Å; V330-Y366 HydrophobicContact CG2-CE2 4.24Å
331	V	84.6	Confident	82.5	Confident	10 Å²	10	55.5 Å²	55.5	6%	0.061	32%	0.317	C	S	.	.	H	α-helix	trans	-60.2	-43.8	173.1	171.9	0	0	0	0	110.8	N327 E328 C334 T335 F345 K347	N327-V331 WeakPolarHBondContact O-CG2 3.46Å; N327-V331 PolarHBondContact O-N 3.21Å; E328-V331 PolarHBondContact O-N 2.95Å; V331-C334 PolarHBondContact O-N 2.96Å; V331-T335 VanDerWaalsContact O-CB 3.26Å; V331-T335 WeakPolarHBondContact O-CB 3.45Å; V331-T335 PolarHBondContact O-N 2.75Å; V331-T335 PolarHBondContact O-OG1 3.18Å; V331-F345 HydrophobicContact CG2-CB 3.66Å; V331-K347 HydrophobicContact CG1-CG 4.36Å
332	E	85.5	Confident	81.4	Confident	124 Å²	124	56.2 Å²	56.2	58%	0.579	32%	0.323	S	S	*	.	H	α-helix	trans	-58.5	-51	177.6	-176	-179	-168	0	0	111.5	E328 V330 T335 N336	E328-E332 PolarHBondContact O-N 3.4Å; V330-E332 VanDerWaalsContact C-N 3.35Å; V330-E332 PolarHBondContact O-N 3.17Å; E332-T335 PolarHBondContact O-N 2.98Å; E332-N336 WeakPolarHBondContact O-CB 2.86Å; E332-N336 PolarHBondContact O-N 2.75Å; E332-N336 PolarHBondContact O-ND2 3.26Å
333	V	86.3	Confident	80.6	Confident	40 Å²	40	59.6 Å²	59.6	24%	0.242	36%	0.361	C	S	.	.	H	α-helix	trans	-63.1	-48.3	178.7	174.2	0	0	0	0	111.6	Q329 V330 T335 N336 T337 C365 Y366	Q329-V333 WeakPolarHBondContact O-CG2 3.48Å; Q329-V333 PolarHBondContact O-N 3.45Å; V330-V333 PolarHBondContact O-N 3.12Å; V333-T335 VanDerWaalsContact C-N 3.29Å; V333-T335 PolarHBondContact O-N 3.05Å; V333-N336 PolarHBondContact O-N 3.03Å; V333-T337 WeakPolarHBondContact O-CB 3.22Å; V333-T337 PolarHBondContact O-N 3.08Å; V333-T337 PolarHBondContact O-OG1 3.28Å; V333-C365 HydrophobicContact CG1-CB 4.35Å; V333-Y366 HydrophobicContact CB-CE1 4.27Å; V333-Y366 HydrophobicContact CB-CE2 4.16Å; V333-Y366 HydrophobicContact CG1-CD1 4.04Å; V333-Y366 HydrophobicContact CG1-CD2 4.03Å; V333-Y366 HydrophobicContact CG1-CE1 4.03Å; V333-Y366 HydrophobicContact CG1-CE2 4.03Å; V333-Y366 HydrophobicContact CG1-CG 4.04Å; V333-Y366 HydrophobicContact CG2-CE1 3.84Å; V333-Y366 HydrophobicContact CG2-CE2 4.5Å
334	C	85.4	Confident	80.2	Confident	0 Å²	0	56.8 Å²	56.8	0%	0	35%	0.35	C	S	.	.	H	α-helix	trans	-59.4	-37.9	176.2	-73.7	0	0	0	0	112.8	V330 V331 S338 S339 A342 C365	V330-C334 WeakPolarHBondContact O-CB 3.44Å; V330-C334 PolarHBondContact O-N 3.17Å; V330-C334 PolarHBondContact O-SG 2.84Å; V330-C334 VanDerWaalsContact O-SG 3.38Å; V331-C334 PolarHBondContact O-N 2.96Å; C334-S338 PolarHBondContact O-N 3.35Å; C334-S339 PolarHBondContact O-N 2.93Å; C334-A342 HydrophobicContact CB-CB 3.85Å; C334-C365 WeakPolarHBondContact CA-SG 3.25Å; C334-C365 HydrophobicContact CB-CB 3.95Å; C334-C365 WeakPolarHBondContact CB-SG 3.38Å; C334-C365 WeakPolarHBondContact SG-CB 3.25Å; C334-C365 CovalentContact SG-SG 2.04Å; C334-C365 PolarHBondContact SG-SG 3.49Å
335	T	84.9	Confident	80.1	Confident	76 Å²	76	54.2 Å²	54.2	47%	0.466	32%	0.321	S	S	.	.	H	α-helix	trans	-67.3	-46.2	177.5	-54.2	0	0	0	0	111.1	V331 E332 V333 T337 S338	V331-T335 VanDerWaalsContact O-CB 3.26Å; V331-T335 WeakPolarHBondContact O-CB 3.45Å; V331-T335 PolarHBondContact O-N 2.75Å; V331-T335 PolarHBondContact O-OG1 3.18Å; E332-T335 PolarHBondContact O-N 2.98Å; V333-T335 VanDerWaalsContact C-N 3.29Å; V333-T335 PolarHBondContact O-N 3.05Å; T335-T337 PolarHBondContact O-N 3.42Å; T335-S338 WeakPolarHBondContact O-CA 3.48Å; T335-S338 PolarHBondContact O-N 2.89Å
336	N	85.7	Confident	79.6	Confident	119 Å²	119	53.9 Å²	53.9	64%	0.636	33%	0.326	S	S	*	.	H	α-helix	trans	-63.5	-39.4	178.1	-74	-31.7	0	0	0	112.3	E332 V333 S338	E332-N336 WeakPolarHBondContact O-CB 2.86Å; E332-N336 PolarHBondContact O-N 2.75Å; E332-N336 PolarHBondContact O-ND2 3.26Å; V333-N336 PolarHBondContact O-N 3.03Å; N336-S338 PolarHBondContact O-N 3.27Å
337	T	79.5	Confident	79.1	Confident	68 Å²	68	60.8 Å²	60.8	42%	0.417	35%	0.354	S	S	.	.	T	Hydrogen-bonded Turn	trans	-72.9	-0.4	172.9	-55.5	0	0	0	0	112.8	V333 T335 S339 C365	V333-T337 WeakPolarHBondContact O-CB 3.22Å; V333-T337 PolarHBondContact O-N 3.08Å; V333-T337 PolarHBondContact O-OG1 3.28Å; T335-T337 PolarHBondContact O-N 3.42Å; T337-S339 PolarHBondContact O-N 3.25Å; T337-C365 PolarHBondContact OG1-O 3.01Å
338	S	77.6	Confident	78.9	Confident	103 Å²	103	64.8 Å²	64.8	72%	0.72	38%	0.375	S	S	*	.	T	Hydrogen-bonded Turn	trans	54.3	36.7	-178.1	-58.8	0	0	0	0	113.6	C334 T335 N336	C334-S338 PolarHBondContact O-N 3.35Å; T335-S338 WeakPolarHBondContact O-CA 3.48Å; T335-S338 PolarHBondContact O-N 2.89Å; N336-S338 PolarHBondContact O-N 3.27Å
339	S	75.6	Confident	78.7	Confident	24 Å²	24	65.5 Å²	65.5	17%	0.168	38%	0.382	C	S	.	.			trans	-70.6	135.2	-176.7	93.2	0	0	0	0	110.8	C334 T337 H341 A342 C365	C334-S339 PolarHBondContact O-N 2.93Å; T337-S339 PolarHBondContact O-N 3.25Å; S339-H341 PolarHBondContact O-N 2.92Å; S339-A342 PolarHBondContact O-N 3.36Å; S339-A342 PolarHBondContact OG-N 3.35Å; S339-C365 PolarHBondContact OG-SG 2.92Å; S339-C365 VanDerWaalsContact OG-SG 3.39Å
340	P	70.4	Confident	78.5	Confident	108 Å²	108	64 Å²	64	70%	0.701	38%	0.381	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.7	1	-179.4	26.6	-32.9	0	0	0	113.4	V177	V177-P340 HydrophobicContact CG1-CG 4.27Å
341	H	73.4	Confident	78.1	Confident	26 Å²	26	69.3 Å²	69.3	12%	0.12	41%	0.414	C	S	.	.	T	Hydrogen-bonded Turn	trans	-117.5	10	-177.3	-59.6	20.9	0	0	0	111.5	S339 G343 L344 V361	S339-H341 PolarHBondContact O-N 2.92Å; H341-G343 PolarHBondContact O-N 2.83Å; H341-L344 WeakPolarHBondContact O-CB 3.28Å; H341-L344 PolarHBondContact O-N 3.49Å; H341-V361 HydrophobicContact CB-CG1 3.71Å; H341-V361 HydrophobicContact CB-CG2 4.08Å
342	A	64.6	Low	77.6	Confident	21 Å²	21	69.8 Å²	69.8	17%	0.174	42%	0.416	C	S	.	.	G	3₁₀ helix	trans	-59.4	-19.3	-179.6	0	0	0	0	0	114.6	C334 S339 L344	C334-A342 HydrophobicContact CB-CB 3.85Å; S339-A342 PolarHBondContact O-N 3.36Å; S339-A342 PolarHBondContact OG-N 3.35Å; A342-L344 VanDerWaalsContact C-N 3.32Å
343	G	66.9	Low	77.1	Confident	81 Å²	81	67.1 Å²	67.1	84%	0.835	42%	0.415	S	S	*	.	G	3₁₀ helix	trans	-81.1	0.1	173.1	0	0	0	0	0	115.5	H341	H341-G343 PolarHBondContact O-N 2.83Å
344	L	76.8	Confident	76.8	Confident	42 Å²	42	65.8 Å²	65.8	22%	0.22	41%	0.407	C	S	.	.	G	3₁₀ helix	trans	-72.2	-26.7	179.9	179.4	59.3	0	0	0	113.5	H341 A342 Y357 K358 V361	H341-L344 WeakPolarHBondContact O-CB 3.28Å; H341-L344 PolarHBondContact O-N 3.49Å; A342-L344 VanDerWaalsContact C-N 3.32Å; L344-Y357 HydrophobicContact CD1-CD1 4.24Å; L344-Y357 HydrophobicContact CD1-CE1 3.72Å; L344-Y357 HydrophobicContact CD2-CD1 3.77Å; L344-Y357 HydrophobicContact CD2-CE1 3.44Å; L344-Y357 VanDerWaalsContact CD2-CE1 3.44Å; L344-Y357 HydrophobicContact CG-CE1 4.24Å; L344-K358 HydrophobicContact CD2-CG 3.92Å; L344-K358 HydrophobicContact CG-CG 4.29Å; L344-V361 HydrophobicContact CD2-CB 4.25Å; L344-V361 HydrophobicContact CD2-CG1 4.33Å; L344-V361 HydrophobicContact CD2-CG2 3.96Å
345	F	78.9	Confident	76.9	Confident	8 Å²	8	66 Å²	66	4%	0.035	41%	0.409	C	S	.	.	S	Bend	trans	-103.2	130.8	-172.9	-52.5	-73.4	0	0	0	110.6	V330 V331 L352 K358 V361 V362	V330-F345 HydrophobicContact CG1-CD2 3.91Å; V330-F345 HydrophobicContact CG1-CE1 4.5Å; V330-F345 HydrophobicContact CG1-CE2 3.85Å; V330-F345 HydrophobicContact CG1-CG 4.29Å; V330-F345 HydrophobicContact CG1-CZ 4.16Å; V331-F345 HydrophobicContact CG2-CB 3.66Å; F345-L352 HydrophobicContact CD1-CD1 3.57Å; F345-L352 HydrophobicContact CD1-CD2 4.5Å; F345-L352 HydrophobicContact CE1-CD1 3.8Å; F345-L352 HydrophobicContact CE1-CD2 4.26Å; F345-K358 HydrophobicContact CE1-CB 3.91Å; F345-K358 HydrophobicContact CE1-CD 4.34Å; F345-K358 HydrophobicContact CE1-CG 3.84Å; F345-K358 HydrophobicContact CZ-CB 4.46Å; F345-V361 HydrophobicContact CE2-CG1 3.77Å; F345-V361 HydrophobicContact CZ-CB 4.24Å; F345-V361 HydrophobicContact CZ-CG1 3.88Å; F345-V362 HydrophobicContact CE1-CG2 4.01Å; F345-V362 HydrophobicContact CE2-CG2 4.19Å; F345-V362 HydrophobicContact CZ-CG2 3.49Å; F345-V362 VanDerWaalsContact CZ-CG2 3.49Å
346	P	74.9	Confident	77	Confident	62 Å²	62	62.5 Å²	62.5	40%	0.403	39%	0.387	S	S	.	.			trans	-65.8	145	175.9	28.7	-34.6	0	0	0	110.4	N327 D348	N327-P346 WeakPolarHBondContact CB-O 3.48Å; P346-D348 PolarHBondContact O-N 2.91Å
347	K	75.8	Confident	77.1	Confident	169 Å²	169	58 Å²	58	74%	0.735	36%	0.361	S	S	*	.	S	Bend	trans	-82	51	-176.9	-64.6	-166.1	179.1	-167.4	0	112.7	V331	V331-K347 HydrophobicContact CG1-CG 4.36Å
348	D	79.2	Confident	77.5	Confident	91 Å²	91	55.3 Å²	55.3	49%	0.487	34%	0.343	S	S	.	.	S	Bend	trans	-111.2	154.7	-174.8	-67.8	-34.7	0	0	0	112.4	N327 E328 P346 S350	N327-D348 WeakPolarHBondContact CB-O 3.34Å; E328-D348 PolarHBondContact N-O 3.1Å; P346-D348 PolarHBondContact O-N 2.91Å; D348-S350 WeakPolarHBondContact CB-OG 3.31Å; D348-S350 PolarHBondContact O-N 3.23Å
349	N	79.3	Confident	78	Confident	116 Å²	116	50.4 Å²	50.4	62%	0.62	31%	0.309	S	S	*	.	S	Bend	trans	-83.8	17.1	172.6	-94.8	-79.6	0	0	0	113.8	E328	E328-N349 PolarHBondContact OE2-ND2 3.49Å
350	S	79.3	Confident	78.6	Confident	55 Å²	55	49.2 Å²	49.2	39%	0.385	30%	0.301	S	S	.	.	S	Bend	trans	-70.5	155.8	168.2	44.7	0	0	0	0	111.5	T326 N327 D348	T326-S350 WeakPolarHBondContact CA-O 3.45Å; N327-S350 PolarHBondContact N-O 2.84Å; N327-S350 PolarHBondContact ND2-O 2.95Å; N327-S350 PolarHBondContact ND2-OG 3.38Å; D348-S350 WeakPolarHBondContact CB-OG 3.31Å; D348-S350 PolarHBondContact O-N 3.23Å
351	T	75.6	Confident	79.4	Confident	112 Å²	112	44.2 Å²	44.2	69%	0.687	27%	0.268	S	S	*	.	B	Isolated β-bridge	trans	-64.8	136.3	167.2	46.2	0	0	0	0	109.8	A353	T351-A353 PolarHBondContact O-N 2.73Å
352	L	74.6	Confident	80.1	Confident	21 Å²	21	43 Å²	43	11%	0.11	26%	0.263	C	S	.	.	P	Polyproline II helix	trans	-65.6	120.5	178.8	172.2	59.2	0	0	0	111	F322 N327 V330 F345 V354 K358 V362	F322-L352 HydrophobicContact CD1-CD2 3.78Å; F322-L352 HydrophobicContact CE1-CD2 3.92Å; N327-L352 WeakPolarHBondContact OD1-CA 3.31Å; N327-L352 WeakPolarHBondContact OD1-CB 3.46Å; N327-L352 WeakPolarHBondContact OD1-CD1 3.49Å; V330-L352 HydrophobicContact CG1-CD2 4.42Å; V330-L352 HydrophobicContact CG2-CD2 4.04Å; F345-L352 HydrophobicContact CD1-CD1 3.57Å; F345-L352 HydrophobicContact CD1-CD2 4.5Å; F345-L352 HydrophobicContact CE1-CD1 3.8Å; F345-L352 HydrophobicContact CE1-CD2 4.26Å; L352-V354 HydrophobicContact CG-CG2 4.19Å; L352-K358 HydrophobicContact CD1-CD 4.46Å; L352-V362 HydrophobicContact CD2-CG2 4.05Å
353	A	74.9	Confident	81.3	Confident	68 Å²	68	42 Å²	42	56%	0.562	26%	0.255	S	S	*	.	P	Polyproline II helix	trans	-73	127.2	164.2	0	0	0	0	0	109	T351 K358	T351-A353 PolarHBondContact O-N 2.73Å; A353-K358 VanDerWaalsContact O-CD 3.3Å; A353-K358 WeakPolarHBondContact O-CD 3.42Å
354	V	79.9	Confident	82.4	Confident	12 Å²	12	38.5 Å²	38.5	7%	0.073	22%	0.218	C	C	.	.			trans	-113.1	132.6	-172.5	-159.9	0	0	0	0	110.4	L94 Q95 A98 F318 F322 L352	L94-V354 HydrophobicContact CD1-CB 3.93Å; L94-V354 HydrophobicContact CD1-CG1 3.49Å; L94-V354 VanDerWaalsContact CD1-CG1 3.49Å; Q95-V354 WeakPolarHBondContact CG-O 3.42Å; Q95-V354 PolarHBondContact NE2-O 2.85Å; A98-V354 HydrophobicContact CB-CB 4.16Å; A98-V354 HydrophobicContact CB-CG2 3.51Å; F318-V354 HydrophobicContact CD1-CG1 4.24Å; F318-V354 HydrophobicContact CE1-CG1 4.38Å; F322-V354 HydrophobicContact CB-CG2 4.35Å; F322-V354 HydrophobicContact CD1-CB 4.33Å; F322-V354 HydrophobicContact CD1-CG1 3.81Å; F322-V354 HydrophobicContact CD1-CG2 3.45Å; F322-V354 VanDerWaalsContact CD1-CG2 3.45Å; F322-V354 HydrophobicContact CE1-CB 4.45Å; F322-V354 HydrophobicContact CE1-CG1 3.52Å; F322-V354 HydrophobicContact CE1-CG2 4Å; F322-V354 HydrophobicContact CG-CG2 4.13Å; F322-V354 HydrophobicContact CZ-CG1 4.04Å; L352-V354 HydrophobicContact CG-CG2 4.19Å
355	D	86.7	Confident	82.9	Confident	5 Å²	5	36.6 Å²	36.6	3%	0.027	21%	0.209	C	C	.	.			trans	-133.2	172.9	173.4	55.2	51.8	0	0	0	109.5	E91 Y357 K358 G359 T436	E91-D355 WeakPolarHBondContact OE1-CA 3.42Å; E91-D355 WeakPolarHBondContact OE1-CB 3.14Å; D355-Y357 PolarHBondContact O-N 3.44Å; D355-Y357 VanDerWaalsContact O-N 3.14Å; D355-Y357 PolarHBondContact OD1-N 3.2Å; D355-Y357 VanDerWaalsContact OD1-N 3.16Å; D355-K358 VanDerWaalsContact OD1-CB 3.32Å; D355-K358 WeakPolarHBondContact OD1-CB 3.27Å; D355-K358 WeakPolarHBondContact OD1-CG 3.45Å; D355-K358 PolarHBondContact OD1-N 3Å; D355-K358 VanDerWaalsContact OD2-CD 3.25Å; D355-K358 WeakPolarHBondContact OD2-CD 3.27Å; D355-K358 VanDerWaalsContact OD2-CE 3.29Å; D355-K358 WeakPolarHBondContact OD2-CE 3.38Å; D355-K358 IonicContact OD2-NZ 2.84Å; D355-K358 PolarHBondContact OD2-NZ 3.29Å; D355-K358 VanDerWaalsContact OD2-NZ 3.1Å; D355-G359 WeakPolarHBondContact O-CA 3.46Å; D355-G359 PolarHBondContact O-N 3.5Å; D355-T436 VanDerWaalsContact CB-CB 3.45Å; D355-T436 HydrophobicContact CB-CG2 3.54Å; D355-T436 VanDerWaalsContact CG-CG2 3.5Å; D355-T436 PolarHBondContact OD2-OG1 2.93Å
356	I	87.9	Confident	83.3	Confident	1 Å²	1	39.7 Å²	39.7	1%	0.005	22%	0.221	C	C	.	.	H	α-helix	trans	-54.2	-35.8	-178.5	-65.6	169	0	0	0	112	P87 E91 L94 I170 G360 W375 I379	P87-I356 HydrophobicContact CB-CD1 3.99Å; E91-I356 HydrophobicContact CB-CD1 4.11Å; E91-I356 HydrophobicContact CB-CG1 4.03Å; E91-I356 HydrophobicContact CG-CG1 4.3Å; E91-I356 PolarHBondContact OE1-N 2.84Å; L94-I356 HydrophobicContact CD2-CG1 3.89Å; I170-I356 HydrophobicContact CD1-CB 4.48Å; I170-I356 HydrophobicContact CG2-CB 4.38Å; I170-I356 HydrophobicContact CG2-CG2 3.81Å; I356-G360 PolarHBondContact O-N 2.95Å; I356-W375 HydrophobicContact CG2-CZ2 4.24Å; I356-W375 PolarHBondContact O-NE1 2.87Å; I356-I379 HydrophobicContact CG2-CB 4.47Å; I356-I379 HydrophobicContact CG2-CD1 3.86Å; I356-I379 HydrophobicContact CG2-CG1 3.82Å; I356-I379 HydrophobicContact CG2-CG2 3.9Å
357	Y	88.1	Confident	84	Confident	24 Å²	24	40.2 Å²	40.2	9%	0.094	22%	0.217	C	C	.	.	H	α-helix	trans	-77.5	-55.9	-175.7	178.6	-113.2	0	0	0	111.7	I170 N173 L174 L344 D355 G359 G360 V361 V432	I170-Y357 HydrophobicContact CG2-CD2 4.14Å; I170-Y357 HydrophobicContact CG2-CG 4.45Å; N173-Y357 VanDerWaalsContact OD1-CE2 3.25Å; N173-Y357 WeakPolarHBondContact OD1-CE2 3.38Å; L174-Y357 HydrophobicContact CD1-CD2 4.29Å; L174-Y357 HydrophobicContact CD2-CD2 3.66Å; L174-Y357 HydrophobicContact CD2-CE2 3.56Å; L174-Y357 HydrophobicContact CG-CD2 3.82Å; L174-Y357 HydrophobicContact CG-CE2 4.02Å; L344-Y357 HydrophobicContact CD1-CD1 4.24Å; L344-Y357 HydrophobicContact CD1-CE1 3.72Å; L344-Y357 HydrophobicContact CD2-CD1 3.77Å; L344-Y357 HydrophobicContact CD2-CE1 3.44Å; L344-Y357 VanDerWaalsContact CD2-CE1 3.44Å; L344-Y357 HydrophobicContact CG-CE1 4.24Å; D355-Y357 PolarHBondContact O-N 3.44Å; D355-Y357 VanDerWaalsContact O-N 3.14Å; D355-Y357 PolarHBondContact OD1-N 3.2Å; D355-Y357 VanDerWaalsContact OD1-N 3.16Å; Y357-G359 PolarHBondContact O-N 3.19Å; Y357-G360 PolarHBondContact O-N 3.02Å; Y357-V361 WeakPolarHBondContact O-CG2 3.45Å; Y357-V361 PolarHBondContact O-N 3.29Å; Y357-V361 VanDerWaalsContact O-N 3.13Å; Y357-V432 HydrophobicContact CD1-CG1 3.83Å; Y357-V432 HydrophobicContact CE1-CG1 4.3Å; Y357-V432 HydrophobicContact CG-CG1 4.39Å
358	K	87.3	Confident	84.6	Confident	12 Å²	12	33.1 Å²	33.1	5%	0.052	19%	0.191	C	C	.	.	H	α-helix	trans	-54.7	-38.2	172.1	-72.1	173.6	-169.2	151.2	0	110.8	L344 F345 L352 A353 D355 V361 V362 E433	L344-K358 HydrophobicContact CD2-CG 3.92Å; L344-K358 HydrophobicContact CG-CG 4.29Å; F345-K358 HydrophobicContact CE1-CB 3.91Å; F345-K358 HydrophobicContact CE1-CD 4.34Å; F345-K358 HydrophobicContact CE1-CG 3.84Å; F345-K358 HydrophobicContact CZ-CB 4.46Å; L352-K358 HydrophobicContact CD1-CD 4.46Å; A353-K358 VanDerWaalsContact O-CD 3.3Å; A353-K358 WeakPolarHBondContact O-CD 3.42Å; D355-K358 VanDerWaalsContact OD1-CB 3.32Å; D355-K358 WeakPolarHBondContact OD1-CB 3.27Å; D355-K358 WeakPolarHBondContact OD1-CG 3.45Å; D355-K358 PolarHBondContact OD1-N 3Å; D355-K358 VanDerWaalsContact OD2-CD 3.25Å; D355-K358 WeakPolarHBondContact OD2-CD 3.27Å; D355-K358 VanDerWaalsContact OD2-CE 3.29Å; D355-K358 WeakPolarHBondContact OD2-CE 3.38Å; D355-K358 IonicContact OD2-NZ 2.84Å; D355-K358 PolarHBondContact OD2-NZ 3.29Å; D355-K358 VanDerWaalsContact OD2-NZ 3.1Å; K358-V361 PolarHBondContact O-N 3.18Å; K358-V362 WeakPolarHBondContact O-CG2 3.35Å; K358-V362 PolarHBondContact O-N 2.8Å; K358-E433 WeakPolarHBondContact CE-OE1 3.35Å; K358-E433 IonicContact NZ-OE1 3.81Å; K358-E433 PolarHBondContact NZ-OE1 3.17Å
359	G	87.3	Confident	85.1	Confident	0 Å²	0	32.9 Å²	32.9	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-54.8	-56.4	176.2	0	0	0	0	0	113	D355 Y357 V361 V362 L363	D355-G359 WeakPolarHBondContact O-CA 3.46Å; D355-G359 PolarHBondContact O-N 3.5Å; Y357-G359 PolarHBondContact O-N 3.19Å; G359-V361 VanDerWaalsContact C-N 3.32Å; G359-V361 PolarHBondContact O-N 3.42Å; G359-V362 PolarHBondContact O-N 3.09Å; G359-L363 WeakPolarHBondContact O-CG 3.08Å; G359-L363 PolarHBondContact O-N 2.85Å; G359-L363 VanDerWaalsContact O-N 3.09Å
360	G	88.6	Confident	85.6	Confident	0 Å²	0	29.7 Å²	29.7	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-61.8	-36.1	177.2	0	0	0	0	0	113.8	I356 Y357 G364 L372	I356-G360 PolarHBondContact O-N 2.95Å; Y357-G360 PolarHBondContact O-N 3.02Å; G360-G364 PolarHBondContact O-N 3.41Å; G360-L372 WeakPolarHBondContact O-CB 3.25Å; G360-L372 WeakPolarHBondContact O-CG 3.46Å
361	V	88.3	Confident	86.2	Confident	2 Å²	2	27.2 Å²	27.2	1%	0.012	17%	0.167	C	C	.	.	H	α-helix	trans	-64.8	-47.1	177.1	173.6	0	0	0	0	111.7	L174 H341 L344 F345 Y357 K358 G359 G364 C365	L174-V361 HydrophobicContact CD2-CG2 4.07Å; H341-V361 HydrophobicContact CB-CG1 3.71Å; H341-V361 HydrophobicContact CB-CG2 4.08Å; L344-V361 HydrophobicContact CD2-CB 4.25Å; L344-V361 HydrophobicContact CD2-CG1 4.33Å; L344-V361 HydrophobicContact CD2-CG2 3.96Å; F345-V361 HydrophobicContact CE2-CG1 3.77Å; F345-V361 HydrophobicContact CZ-CB 4.24Å; F345-V361 HydrophobicContact CZ-CG1 3.88Å; Y357-V361 WeakPolarHBondContact O-CG2 3.45Å; Y357-V361 PolarHBondContact O-N 3.29Å; Y357-V361 VanDerWaalsContact O-N 3.13Å; K358-V361 PolarHBondContact O-N 3.18Å; G359-V361 VanDerWaalsContact C-N 3.32Å; G359-V361 PolarHBondContact O-N 3.42Å; V361-G364 CarbonylContact O-C 3.58Å; V361-G364 WeakPolarHBondContact O-CA 3.4Å; V361-G364 PolarHBondContact O-N 2.92Å; V361-C365 PolarHBondContact O-N 2.89Å; V361-C365 PolarHBondContact O-SG 3.17Å
362	V	88.2	Confident	87	Confident	1 Å²	1	23 Å²	23	1%	0.006	14%	0.14	C	C	.	.	H	α-helix	trans	-65.3	-42	178.8	172.7	0	0	0	0	111.3	F322 V330 F345 L352 K358 G359 G364 C365 Y366	F322-V362 HydrophobicContact CD1-CG1 4.38Å; F322-V362 HydrophobicContact CE1-CB 3.64Å; F322-V362 HydrophobicContact CE1-CG1 3.69Å; F322-V362 HydrophobicContact CE1-CG2 3.71Å; F322-V362 HydrophobicContact CE2-CB 4.4Å; F322-V362 HydrophobicContact CE2-CG1 4.07Å; F322-V362 HydrophobicContact CZ-CB 3.46Å; F322-V362 VanDerWaalsContact CZ-CB 3.46Å; F322-V362 HydrophobicContact CZ-CG1 3.52Å; F322-V362 HydrophobicContact CZ-CG2 4.06Å; V330-V362 HydrophobicContact CG1-CG2 3.57Å; F345-V362 HydrophobicContact CE1-CG2 4.01Å; F345-V362 HydrophobicContact CE2-CG2 4.19Å; F345-V362 HydrophobicContact CZ-CG2 3.49Å; F345-V362 VanDerWaalsContact CZ-CG2 3.49Å; L352-V362 HydrophobicContact CD2-CG2 4.05Å; K358-V362 WeakPolarHBondContact O-CG2 3.35Å; K358-V362 PolarHBondContact O-N 2.8Å; G359-V362 PolarHBondContact O-N 3.09Å; V362-G364 PolarHBondContact O-N 3.08Å; V362-C365 PolarHBondContact O-N 2.97Å; V362-Y366 HydrophobicContact CG1-CD2 3.57Å; V362-Y366 HydrophobicContact CG1-CE2 3.74Å; V362-Y366 WeakPolarHBondContact O-CD2 3.42Å; V362-Y366 PolarHBondContact O-N 2.73Å
363	L	89.5	Confident	87.9	Confident	0 Å²	0	26.4 Å²	26.4	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-55.8	-43.4	172.3	-69.9	175.2	0	0	0	111	V229 V317 F318 G359 C365 F367 A371 W375	V229-L363 HydrophobicContact CG2-CD2 4.34Å; V317-L363 HydrophobicContact CG1-CD1 4.43Å; V317-L363 HydrophobicContact CG1-CD2 3.83Å; F318-L363 HydrophobicContact CE2-CD1 4.38Å; F318-L363 HydrophobicContact CZ-CD1 3.88Å; F318-L363 HydrophobicContact CZ-CG 4.49Å; G359-L363 WeakPolarHBondContact O-CG 3.08Å; G359-L363 PolarHBondContact O-N 2.85Å; G359-L363 VanDerWaalsContact O-N 3.09Å; L363-C365 PolarHBondContact O-N 3.31Å; L363-F367 HydrophobicContact CD2-CD2 3.99Å; L363-F367 HydrophobicContact CD2-CE2 4.21Å; L363-F367 PolarHBondContact O-N 3.49Å; L363-A371 HydrophobicContact CB-CB 4.17Å; L363-W375 HydrophobicContact CD1-CB 4.27Å; L363-W375 HydrophobicContact CD1-CD2 4.16Å; L363-W375 HydrophobicContact CD1-CE3 4.14Å; L363-W375 HydrophobicContact CD1-CG 4.23Å
364	G	88.4	Confident	88.9	Confident	7 Å²	7	25.2 Å²	25.2	7%	0.072	14%	0.136	C	C	.	.	H	α-helix	trans	-59.3	-37.4	172.3	0	0	0	0	0	115.2	G360 V361 V362 G368	G360-G364 PolarHBondContact O-N 3.41Å; V361-G364 CarbonylContact O-C 3.58Å; V361-G364 WeakPolarHBondContact O-CA 3.4Å; V361-G364 PolarHBondContact O-N 2.92Å; V362-G364 PolarHBondContact O-N 3.08Å; G364-G368 CarbonylContact O-C 3.23Å; G364-G368 VanDerWaalsContact O-C 3.23Å; G364-G368 WeakPolarHBondContact O-CA 3.21Å; G364-G368 PolarHBondContact O-N 3.34Å
365	C	88.4	Confident	89.7	Confident	3 Å²	3	24.8 Å²	24.8	2%	0.02	13%	0.133	C	C	.	.	H	α-helix	trans	-75.7	-38.6	179.8	-63	0	0	0	0	113.7	V333 C334 T337 S339 V361 V362 L363	V333-C365 HydrophobicContact CG1-CB 4.35Å; C334-C365 WeakPolarHBondContact CA-SG 3.25Å; C334-C365 HydrophobicContact CB-CB 3.95Å; C334-C365 WeakPolarHBondContact CB-SG 3.38Å; C334-C365 WeakPolarHBondContact SG-CB 3.25Å; C334-C365 CovalentContact SG-SG 2.04Å; C334-C365 PolarHBondContact SG-SG 3.49Å; T337-C365 PolarHBondContact OG1-O 3.01Å; S339-C365 PolarHBondContact OG-SG 2.92Å; S339-C365 VanDerWaalsContact OG-SG 3.39Å; V361-C365 PolarHBondContact O-N 2.89Å; V361-C365 PolarHBondContact O-SG 3.17Å; V362-C365 PolarHBondContact O-N 2.97Å; L363-C365 PolarHBondContact O-N 3.31Å
366	Y	87.8	Confident	90.1	Very high	72 Å²	72	24.5 Å²	24.5	28%	0.282	13%	0.132	S	C	.	.	H	α-helix	trans	-90.1	-37.7	-175.7	-80.3	-94.5	0	0	0	113.7	V330 V333 V362	V330-Y366 HydrophobicContact CG2-CE2 4.24Å; V333-Y366 HydrophobicContact CB-CE1 4.27Å; V333-Y366 HydrophobicContact CB-CE2 4.16Å; V333-Y366 HydrophobicContact CG1-CD1 4.04Å; V333-Y366 HydrophobicContact CG1-CD2 4.03Å; V333-Y366 HydrophobicContact CG1-CE1 4.03Å; V333-Y366 HydrophobicContact CG1-CE2 4.03Å; V333-Y366 HydrophobicContact CG1-CG 4.04Å; V333-Y366 HydrophobicContact CG2-CE1 3.84Å; V333-Y366 HydrophobicContact CG2-CE2 4.5Å; V362-Y366 HydrophobicContact CG1-CD2 3.57Å; V362-Y366 HydrophobicContact CG1-CE2 3.74Å; V362-Y366 WeakPolarHBondContact O-CD2 3.42Å; V362-Y366 PolarHBondContact O-N 2.73Å
367	F	89.1	Confident	90.5	Very high	74 Å²	74	27.5 Å²	27.5	33%	0.325	15%	0.15	S	C	.	.	H	α-helix	trans	-113.4	-1.3	-174	-54.3	-78.2	0	0	0	113.1	T228 V229 A321 L363 A371	T228-F367 HydrophobicContact CG2-CB 4.1Å; T228-F367 HydrophobicContact CG2-CD1 4.22Å; T228-F367 HydrophobicContact CG2-CG 4.42Å; V229-F367 HydrophobicContact CB-CE1 4.32Å; V229-F367 HydrophobicContact CB-CZ 4.17Å; V229-F367 HydrophobicContact CG1-CE1 4.48Å; V229-F367 HydrophobicContact CG1-CE2 4.5Å; V229-F367 HydrophobicContact CG1-CZ 3.97Å; V229-F367 HydrophobicContact CG2-CD1 4.26Å; V229-F367 HydrophobicContact CG2-CD2 3.97Å; V229-F367 HydrophobicContact CG2-CE1 4.01Å; V229-F367 HydrophobicContact CG2-CE2 3.72Å; V229-F367 HydrophobicContact CG2-CG 4.26Å; V229-F367 HydrophobicContact CG2-CZ 3.74Å; A321-F367 HydrophobicContact CB-CE2 4.2Å; L363-F367 HydrophobicContact CD2-CD2 3.99Å; L363-F367 HydrophobicContact CD2-CE2 4.21Å; L363-F367 PolarHBondContact O-N 3.49Å; F367-A371 HydrophobicContact CB-CB 4.08Å
368	G	88.9	Confident	90.9	Very high	19 Å²	19	26.4 Å²	26.4	20%	0.196	15%	0.146	C	C	.	.			trans	95	164.7	174.9	0	0	0	0	0	113.7	G364 A370 A371	G364-G368 CarbonylContact O-C 3.23Å; G364-G368 VanDerWaalsContact O-C 3.23Å; G364-G368 WeakPolarHBondContact O-CA 3.21Å; G364-G368 PolarHBondContact O-N 3.34Å; G368-A370 PolarHBondContact O-N 3.24Å; G368-A371 WeakPolarHBondContact O-CB 3.09Å; G368-A371 PolarHBondContact O-N 2.76Å
369	P	88.2	Confident	91.2	Very high	87 Å²	87	25.9 Å²	25.9	57%	0.565	14%	0.143	S	C	*	.	H	α-helix	trans	-62.7	-19.9	-168.8	24.2	-35	0	0	0	114.5	A371 L372 Y373	P369-A371 VanDerWaalsContact C-N 3.33Å; P369-A371 PolarHBondContact O-N 3.49Å; P369-L372 PolarHBondContact O-N 2.96Å; P369-Y373 HydrophobicContact CB-CE2 4.34Å; P369-Y373 WeakPolarHBondContact O-CD2 3.43Å; P369-Y373 PolarHBondContact O-N 3.19Å
370	A	91.2	Very high	91.6	Very high	49 Å²	49	28.1 Å²	28.1	41%	0.405	16%	0.155	S	C	.	.	H	α-helix	trans	-60.3	-42.1	173.4	0	0	0	0	0	112.1	G368 L372 Y373 I374	G368-A370 PolarHBondContact O-N 3.24Å; A370-L372 PolarHBondContact O-N 3.05Å; A370-Y373 PolarHBondContact O-N 3.39Å; A370-I374 WeakPolarHBondContact O-CB 3.38Å; A370-I374 VanDerWaalsContact O-CG1 3.26Å; A370-I374 WeakPolarHBondContact O-CG1 3.45Å; A370-I374 PolarHBondContact O-N 3.13Å
371	A	91.8	Very high	91.9	Very high	2 Å²	2	28.5 Å²	28.5	2%	0.017	16%	0.158	C	C	.	.	H	α-helix	trans	-62.7	-42.2	180	0	0	0	0	0	112.1	E225 L363 F367 G368 P369 Y373 I374 W375	E225-A371 WeakPolarHBondContact OE1-CA 3.42Å; E225-A371 WeakPolarHBondContact OE2-CB 3.43Å; L363-A371 HydrophobicContact CB-CB 4.17Å; F367-A371 HydrophobicContact CB-CB 4.08Å; G368-A371 WeakPolarHBondContact O-CB 3.09Å; G368-A371 PolarHBondContact O-N 2.76Å; P369-A371 VanDerWaalsContact C-N 3.33Å; P369-A371 PolarHBondContact O-N 3.49Å; A371-Y373 PolarHBondContact O-N 2.87Å; A371-I374 PolarHBondContact O-N 3.31Å; A371-W375 VanDerWaalsContact O-CB 3.27Å; A371-W375 WeakPolarHBondContact O-CB 3.35Å; A371-W375 PolarHBondContact O-N 3.2Å
372	L	92.2	Very high	92.2	Very high	23 Å²	23	28.4 Å²	28.4	12%	0.12	16%	0.157	C	C	.	.	H	α-helix	trans	-58.4	-45.9	175.7	-176.3	159.4	0	0	0	111.9	L174 G360 P369 A370 A376	L174-L372 HydrophobicContact CB-CD2 4.14Å; L174-L372 HydrophobicContact CD2-CD1 4.46Å; L174-L372 HydrophobicContact CD2-CD2 4.18Å; L174-L372 HydrophobicContact CD2-CG 4.32Å; G360-L372 WeakPolarHBondContact O-CB 3.25Å; G360-L372 WeakPolarHBondContact O-CG 3.46Å; P369-L372 PolarHBondContact O-N 2.96Å; A370-L372 PolarHBondContact O-N 3.05Å; L372-A376 WeakPolarHBondContact O-CB 3.5Å; L372-A376 PolarHBondContact O-N 3.48Å
373	Y	94	Very high	92.4	Very high	94 Å²	94	28.3 Å²	28.3	37%	0.369	16%	0.157	S	C	.	.	H	α-helix	trans	-71.7	-36.5	178.7	-63.2	-57	0	0	0	112.6	L175 V177 P369 A370 A371 A376 V377	L175-Y373 HydrophobicContact CD2-CD1 4.3Å; V177-Y373 HydrophobicContact CG2-CE1 4.12Å; V177-Y373 WeakPolarHBondContact CG2-OH 3.4Å; P369-Y373 HydrophobicContact CB-CE2 4.34Å; P369-Y373 WeakPolarHBondContact O-CD2 3.43Å; P369-Y373 PolarHBondContact O-N 3.19Å; A370-Y373 PolarHBondContact O-N 3.39Å; A371-Y373 PolarHBondContact O-N 2.87Å; Y373-A376 PolarHBondContact O-N 3.47Å; Y373-V377 WeakPolarHBondContact O-CG2 3.36Å; Y373-V377 PolarHBondContact O-N 2.94Å
374	I	95.8	Very high	92.4	Very high	43 Å²	43	30.8 Å²	30.8	22%	0.221	17%	0.169	C	C	.	.	H	α-helix	trans	-66.6	-44.1	177.5	-72.6	169.6	0	0	0	110.6	T221 Y224 E225 A370 A371 V377 G378	T221-I374 WeakPolarHBondContact CB-O 3.33Å; T221-I374 HydrophobicContact CG2-CG2 4Å; T221-I374 WeakPolarHBondContact CG2-O 3.38Å; Y224-I374 HydrophobicContact CD1-CD1 3.47Å; Y224-I374 VanDerWaalsContact CD1-CD1 3.47Å; Y224-I374 HydrophobicContact CD1-CG2 4.06Å; Y224-I374 HydrophobicContact CE1-CD1 3.43Å; Y224-I374 VanDerWaalsContact CE1-CD1 3.43Å; Y224-I374 HydrophobicContact CG-CD1 4.09Å; E225-I374 WeakPolarHBondContact OE1-CG2 3.22Å; A370-I374 WeakPolarHBondContact O-CB 3.38Å; A370-I374 VanDerWaalsContact O-CG1 3.26Å; A370-I374 WeakPolarHBondContact O-CG1 3.45Å; A370-I374 PolarHBondContact O-N 3.13Å; A371-I374 PolarHBondContact O-N 3.31Å; I374-V377 PolarHBondContact O-N 3.03Å; I374-G378 PolarHBondContact O-N 2.77Å
375	W	95.3	Very high	92.5	Very high	2 Å²	2	30.5 Å²	30.5	1%	0.008	17%	0.165	C	C	.	.	H	α-helix	trans	-53.8	-52.4	168.5	176.3	-105.4	0	0	0	111.5	I90 L94 F222 V314 F318 I356 L363 A371 V377 G378 I379	I90-W375 HydrophobicContact CG2-CH2 3.65Å; I90-W375 HydrophobicContact CG2-CZ2 4.33Å; I90-W375 HydrophobicContact CG2-CZ3 4.41Å; L94-W375 HydrophobicContact CD2-CH2 4.04Å; L94-W375 HydrophobicContact CD2-CZ2 3.86Å; F222-W375 AromaticContact CD1-CE3 3.82Å; F222-W375 HydrophobicContact CD1-CE3 3.82Å; F222-W375 AromaticContact CD1-CZ3 3.76Å; F222-W375 HydrophobicContact CD1-CZ3 3.76Å; F222-W375 HydrophobicContact CE1-CD2 4.38Å; F222-W375 AromaticContact CE1-CE3 3.5Å; F222-W375 HydrophobicContact CE1-CE3 3.5Å; F222-W375 VanDerWaalsContact CE1-CE3 3.5Å; F222-W375 HydrophobicContact CE1-CH2 4.38Å; F222-W375 AromaticContact CE1-CZ3 3.47Å; F222-W375 HydrophobicContact CE1-CZ3 3.47Å; F222-W375 VanDerWaalsContact CE1-CZ3 3.47Å; F222-W375 HydrophobicContact CZ-CZ3 4.49Å; V314-W375 HydrophobicContact CG1-CH2 4.43Å; F318-W375 HydrophobicContact CE2-CE3 4.14Å; F318-W375 AromaticContact CE2-CH2 3.44Å; F318-W375 HydrophobicContact CE2-CH2 3.44Å; F318-W375 VanDerWaalsContact CE2-CH2 3.44Å; F318-W375 HydrophobicContact CE2-CZ2 4.14Å; F318-W375 AromaticContact CE2-CZ3 3.45Å; F318-W375 HydrophobicContact CE2-CZ3 3.45Å; F318-W375 VanDerWaalsContact CE2-CZ3 3.45Å; F318-W375 HydrophobicContact CZ-CD2 4.42Å; F318-W375 HydrophobicContact CZ-CE3 4.2Å; F318-W375 AromaticContact CZ-CH2 3.57Å; F318-W375 HydrophobicContact CZ-CH2 3.57Å; F318-W375 AromaticContact CZ-CZ2 3.77Å; F318-W375 HydrophobicContact CZ-CZ2 3.77Å; F318-W375 AromaticContact CZ-CZ3 3.81Å; F318-W375 HydrophobicContact CZ-CZ3 3.81Å; I356-W375 HydrophobicContact CG2-CZ2 4.24Å; I356-W375 PolarHBondContact O-NE1 2.87Å; L363-W375 HydrophobicContact CD1-CB 4.27Å; L363-W375 HydrophobicContact CD1-CD2 4.16Å; L363-W375 HydrophobicContact CD1-CE3 4.14Å; L363-W375 HydrophobicContact CD1-CG 4.23Å; A371-W375 VanDerWaalsContact O-CB 3.27Å; A371-W375 WeakPolarHBondContact O-CB 3.35Å; A371-W375 PolarHBondContact O-N 3.2Å; W375-V377 PolarHBondContact O-N 3.45Å; W375-G378 WeakPolarHBondContact O-CA 3.33Å; W375-G378 PolarHBondContact O-N 3.5Å; W375-I379 HydrophobicContact CD2-CG1 4.19Å; W375-I379 HydrophobicContact CH2-CD1 4Å; W375-I379 HydrophobicContact CZ2-CD1 3.7Å; W375-I379 HydrophobicContact CZ2-CG1 4.06Å; W375-I379 WeakPolarHBondContact O-CG1 3.2Å; W375-I379 PolarHBondContact O-N 3.25Å
376	A	95.3	Very high	92.4	Very high	0 Å²	0	30.3 Å²	30.3	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-64.7	-34.3	-178	0	0	0	0	0	113.4	A171 L174 L175 L372 Y373 L380	A171-A376 WeakPolarHBondContact CB-O 3.44Å; L174-A376 HydrophobicContact CB-CB 3.81Å; L174-A376 HydrophobicContact CD1-CB 4.24Å; L175-A376 HydrophobicContact CD2-CB 3.94Å; L175-A376 HydrophobicContact CG-CB 3.81Å; L372-A376 WeakPolarHBondContact O-CB 3.5Å; L372-A376 PolarHBondContact O-N 3.48Å; Y373-A376 PolarHBondContact O-N 3.47Å; A376-L380 WeakPolarHBondContact O-CB 3.49Å; A376-L380 PolarHBondContact O-N 3.31Å
377	V	96.5	Very high	92.3	Very high	64 Å²	64	27 Å²	27	39%	0.388	15%	0.152	S	C	.	.	H	α-helix	trans	-65	-40.7	170.7	170.2	0	0	0	0	111.4	L175 I217 T221 Y373 I374 W375 L380 A381	L175-V377 HydrophobicContact CD2-CG2 4Å; I217-V377 HydrophobicContact CG2-CG1 3.86Å; T221-V377 HydrophobicContact CG2-CB 4.38Å; T221-V377 HydrophobicContact CG2-CG1 4.13Å; Y373-V377 WeakPolarHBondContact O-CG2 3.36Å; Y373-V377 PolarHBondContact O-N 2.94Å; I374-V377 PolarHBondContact O-N 3.03Å; W375-V377 PolarHBondContact O-N 3.45Å; V377-L380 PolarHBondContact O-N 2.9Å; V377-A381 PolarHBondContact O-N 3.09Å
378	G	96.1	Very high	92.1	Very high	0 Å²	0	23.9 Å²	23.9	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-61.8	-47.7	175.8	0	0	0	0	0	112.6	T221 I374 W375 L380 A381 A382	T221-G378 VanDerWaalsContact OG1-CA 3.32Å; T221-G378 WeakPolarHBondContact OG1-CA 3.49Å; I374-G378 PolarHBondContact O-N 2.77Å; W375-G378 WeakPolarHBondContact O-CA 3.33Å; W375-G378 PolarHBondContact O-N 3.5Å; G378-L380 VanDerWaalsContact C-N 3.35Å; G378-L380 PolarHBondContact O-N 3.11Å; G378-A381 PolarHBondContact O-N 2.83Å; G378-A382 PolarHBondContact O-N 3.07Å
379	I	95.3	Very high	91.9	Very high	1 Å²	1	23 Å²	23	1%	0.005	13%	0.129	C	C	.	.	H	α-helix	trans	-64.4	-37.7	176.7	-61.6	-64.9	0	0	0	111.8	I90 G167 A171 F222 I356 W375 A382 G383	I90-I379 HydrophobicContact CB-CD1 4.49Å; I90-I379 HydrophobicContact CD1-CD1 4.26Å; I90-I379 HydrophobicContact CG2-CD1 3.69Å; G167-I379 WeakPolarHBondContact O-CG2 3.16Å; A171-I379 HydrophobicContact CB-CB 4.18Å; A171-I379 HydrophobicContact CB-CG2 3.99Å; F222-I379 HydrophobicContact CZ-CD1 4.24Å; I356-I379 HydrophobicContact CG2-CB 4.47Å; I356-I379 HydrophobicContact CG2-CD1 3.86Å; I356-I379 HydrophobicContact CG2-CG1 3.82Å; I356-I379 HydrophobicContact CG2-CG2 3.9Å; W375-I379 HydrophobicContact CD2-CG1 4.19Å; W375-I379 HydrophobicContact CH2-CD1 4Å; W375-I379 HydrophobicContact CZ2-CD1 3.7Å; W375-I379 HydrophobicContact CZ2-CG1 4.06Å; W375-I379 WeakPolarHBondContact O-CG1 3.2Å; W375-I379 PolarHBondContact O-N 3.25Å; I379-A382 WeakPolarHBondContact O-CB 3.42Å; I379-A382 PolarHBondContact O-N 2.84Å; I379-G383 PolarHBondContact O-N 3.48Å
380	L	94.9	Very high	91.8	Very high	48 Å²	48	18.8 Å²	18.8	25%	0.251	10%	0.102	S	C	.	.	H	α-helix	trans	-64.8	-42.2	174.7	-171.1	61.4	0	0	0	111.2	A171 I172 L175 A376 V377 G378 A382 Q384	A171-L380 HydrophobicContact CB-CB 3.89Å; A171-L380 HydrophobicContact CB-CD1 4.39Å; I172-L380 HydrophobicContact CG1-CD1 4.24Å; L175-L380 HydrophobicContact CD1-CD2 3.9Å; A376-L380 WeakPolarHBondContact O-CB 3.49Å; A376-L380 PolarHBondContact O-N 3.31Å; V377-L380 PolarHBondContact O-N 2.9Å; G378-L380 VanDerWaalsContact C-N 3.35Å; G378-L380 PolarHBondContact O-N 3.11Å; L380-A382 VanDerWaalsContact C-N 3.34Å; L380-A382 PolarHBondContact O-N 3.01Å; L380-Q384 HydrophobicContact CD1-CG 4.1Å; L380-Q384 HydrophobicContact CG-CG 4.28Å; L380-Q384 VanDerWaalsContact O-CB 3.3Å; L380-Q384 WeakPolarHBondContact O-CB 3.48Å; L380-Q384 WeakPolarHBondContact O-CG 3.21Å; L380-Q384 PolarHBondContact O-N 3.28Å
381	A	94.8	Very high	91.4	Very high	7 Å²	7	16.8 Å²	16.8	6%	0.058	8%	0.084	C	C	.	.	H	α-helix	trans	-62.4	-40.7	174.8	0	0	0	0	0	112.1	L214 I217 M218 V377 G378 S385	L214-A381 HydrophobicContact CD2-CB 4.31Å; I217-A381 HydrophobicContact CB-CB 4.2Å; I217-A381 HydrophobicContact CG2-CB 3.81Å; M218-A381 HydrophobicContact CG-CB 3.91Å; V377-A381 PolarHBondContact O-N 3.09Å; G378-A381 PolarHBondContact O-N 2.83Å; A381-S385 WeakPolarHBondContact O-CB 3.34Å; A381-S385 PolarHBondContact O-N 3.22Å; A381-S385 PolarHBondContact O-OG 3.36Å
382	A	94.1	Very high	90.9	Very high	0 Å²	0	17 Å²	17	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-58.1	-59.5	173.6	0	0	0	0	0	111.9	L85 P87 I90 M218 G378 I379 L380 Q384 S385 S386	L85-A382 WeakPolarHBondContact O-CB 3.5Å; P87-A382 HydrophobicContact CG-CB 4.34Å; I90-A382 HydrophobicContact CD1-CB 3.66Å; M218-A382 WeakPolarHBondContact SD-CA 3.39Å; M218-A382 HydrophobicContact SD-CB 3.64Å; G378-A382 PolarHBondContact O-N 3.07Å; I379-A382 WeakPolarHBondContact O-CB 3.42Å; I379-A382 PolarHBondContact O-N 2.84Å; L380-A382 VanDerWaalsContact C-N 3.34Å; L380-A382 PolarHBondContact O-N 3.01Å; A382-Q384 PolarHBondContact O-N 2.88Å; A382-S385 PolarHBondContact O-N 2.78Å; A382-S385 VanDerWaalsContact O-N 3.1Å; A382-S385 PolarHBondContact O-OG 3.06Å; A382-S386 PolarHBondContact O-N 2.94Å
383	G	92.3	Very high	90.7	Very high	0 Å²	0	16 Å²	16	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-58.6	-45.7	-178.3	0	0	0	0	0	112.9	I379 S385 S386 T387	I379-G383 PolarHBondContact O-N 3.48Å; G383-S385 VanDerWaalsContact C-N 3.32Å; G383-S385 PolarHBondContact O-N 3.43Å; G383-S386 PolarHBondContact O-N 3.4Å; G383-T387 WeakPolarHBondContact O-CB 3.3Å; G383-T387 PolarHBondContact O-N 3.3Å; G383-T387 PolarHBondContact O-OG1 3.4Å
384	Q	90.6	Very high	90.4	Very high	52 Å²	52	11.5 Å²	11.5	24%	0.243	6%	0.062	C	C	.	.	H	α-helix	trans	-64.2	-35.2	176.1	-65.6	-63.5	-83.5	0	0	112.9	D192 L380 A382 M388	D192-Q384 PolarHBondContact OD2-NE2 3.12Å; L380-Q384 HydrophobicContact CD1-CG 4.1Å; L380-Q384 HydrophobicContact CG-CG 4.28Å; L380-Q384 VanDerWaalsContact O-CB 3.3Å; L380-Q384 WeakPolarHBondContact O-CB 3.48Å; L380-Q384 WeakPolarHBondContact O-CG 3.21Å; L380-Q384 PolarHBondContact O-N 3.28Å; A382-Q384 PolarHBondContact O-N 2.88Å; Q384-M388 WeakPolarHBondContact O-CE 3.29Å
385	S	89.8	Confident	89.9	Confident	0 Å²	0	10 Å²	10	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-68.2	-43.9	175.6	73.5	0	0	0	0	111.9	I82 A381 A382 G383 M388	I82-S385 WeakPolarHBondContact CG2-OG 3.42Å; A381-S385 WeakPolarHBondContact O-CB 3.34Å; A381-S385 PolarHBondContact O-N 3.22Å; A381-S385 PolarHBondContact O-OG 3.36Å; A382-S385 PolarHBondContact O-N 2.78Å; A382-S385 VanDerWaalsContact O-N 3.1Å; A382-S385 PolarHBondContact O-OG 3.06Å; G383-S385 VanDerWaalsContact C-N 3.32Å; G383-S385 PolarHBondContact O-N 3.43Å; S385-M388 PolarHBondContact O-N 2.96Å
386	S	87.8	Confident	89.6	Confident	0 Å²	0	10.3 Å²	10.3	0%	0	6%	0.056	C	C	.	.	H	α-helix	trans	-76	-30.8	-176	-171.6	0	0	0	0	113.4	E164 A382 G383 M388 T389 G390	E164-S386 PolarHBondContact OE1-OG 3.37Å; A382-S386 PolarHBondContact O-N 2.94Å; G383-S386 PolarHBondContact O-N 3.4Å; S386-M388 PolarHBondContact O-N 3.02Å; S386-T389 VanDerWaalsContact CA-OG1 3.29Å; S386-T389 WeakPolarHBondContact CA-OG1 3.41Å; S386-T389 PolarHBondContact O-N 3.2Å; S386-T389 PolarHBondContact O-OG1 3.19Å; S386-G390 PolarHBondContact O-N 3.33Å
387	T	85.5	Confident	89.3	Confident	3 Å²	3	10.3 Å²	10.3	2%	0.018	6%	0.056	C	C	.	.	H	α-helix	trans	-43.3	-42.4	167.2	-79.6	0	0	0	0	113	E164 D192 G383 T391 R416	E164-T387 WeakPolarHBondContact OE2-CA 3.29Å; E164-T387 PolarHBondContact OE2-N 3.16Å; D192-T387 WeakPolarHBondContact OD1-CG2 3.49Å; G383-T387 WeakPolarHBondContact O-CB 3.3Å; G383-T387 PolarHBondContact O-N 3.3Å; G383-T387 PolarHBondContact O-OG1 3.4Å; T387-T391 WeakPolarHBondContact O-CG2 3.32Å; T387-T391 PolarHBondContact O-N 3.18Å; T387-T391 PolarHBondContact O-OG1 2.75Å; T387-R416 PolarHBondContact OG1-NH1 3.42Å
388	M	83.3	Confident	88.9	Confident	7 Å²	7	8 Å²	8	3%	0.034	4%	0.041	C	C	.	.	H	α-helix	trans	-77.7	-38.7	-179.4	-59.3	-176.8	-85.2	0	0	111.5	F196 L199 F210 F211 L214 Q384 S385 S386 T391 Y392	F196-M388 HydrophobicContact CB-CG 4.13Å; F196-M388 HydrophobicContact CD2-CB 3.89Å; F196-M388 HydrophobicContact CD2-CG 3.45Å; F196-M388 VanDerWaalsContact CD2-CG 3.45Å; F196-M388 HydrophobicContact CD2-SD 3.85Å; F196-M388 HydrophobicContact CE2-CB 4.01Å; F196-M388 HydrophobicContact CE2-CG 4.09Å; F196-M388 HydrophobicContact CG-CG 3.96Å; L199-M388 HydrophobicContact CD1-SD 4.48Å; F210-M388 HydrophobicContact CD1-CE 3.97Å; F210-M388 HydrophobicContact CD1-SD 4.34Å; F210-M388 HydrophobicContact CE1-CE 3.56Å; F210-M388 HydrophobicContact CE1-SD 4.09Å; F211-M388 HydrophobicContact CD1-CE 3.96Å; F211-M388 HydrophobicContact CE1-CB 3.81Å; F211-M388 HydrophobicContact CE1-CE 3.42Å; F211-M388 VanDerWaalsContact CE1-CE 3.42Å; F211-M388 HydrophobicContact CE1-CG 4.46Å; F211-M388 HydrophobicContact CE1-SD 4.07Å; F211-M388 HydrophobicContact CZ-CB 3.53Å; F211-M388 HydrophobicContact CZ-CE 4.05Å; F211-M388 HydrophobicContact CZ-CG 4.4Å; F211-M388 HydrophobicContact CZ-SD 4.07Å; L214-M388 HydrophobicContact CD1-CE 3.76Å; Q384-M388 WeakPolarHBondContact O-CE 3.29Å; S385-M388 PolarHBondContact O-N 2.96Å; S386-M388 PolarHBondContact O-N 3.02Å; M388-T391 WeakPolarHBondContact CA-OG1 3.39Å; M388-T391 PolarHBondContact O-OG1 2.92Å; M388-Y392 WeakPolarHBondContact O-CD2 3.25Å; M388-Y392 PolarHBondContact O-N 2.99Å
389	T	85.6	Confident	88.5	Confident	0 Å²	0	10.1 Å²	10.1	0%	0	5%	0.05	C	C	.	.	H	α-helix	trans	-69.7	-34.6	176.1	48.9	0	0	0	0	113.5	L79 I82 L271 S386 S393	L79-T389 WeakPolarHBondContact O-CG2 3.36Å; I82-T389 HydrophobicContact CB-CG2 4.21Å; I82-T389 HydrophobicContact CG2-CG2 3.92Å; L271-T389 HydrophobicContact CD2-CG2 3.88Å; S386-T389 VanDerWaalsContact CA-OG1 3.29Å; S386-T389 WeakPolarHBondContact CA-OG1 3.41Å; S386-T389 PolarHBondContact O-N 3.2Å; S386-T389 PolarHBondContact O-OG1 3.19Å; T389-S393 WeakPolarHBondContact O-CB 3.4Å; T389-S393 PolarHBondContact O-N 3.31Å; T389-S393 PolarHBondContact O-OG 3.38Å
390	G	85.6	Confident	88.2	Confident	0 Å²	0	10.2 Å²	10.2	0%	0	5%	0.052	C	C	.	.	H	α-helix	trans	-62.5	-48.4	172.7	0	0	0	0	0	112	S386 Y392 S393 G394	S386-G390 PolarHBondContact O-N 3.33Å; G390-Y392 PolarHBondContact O-N 3.37Å; G390-S393 WeakPolarHBondContact O-CB 3.32Å; G390-S393 PolarHBondContact O-N 3.24Å; G390-S393 VanDerWaalsContact O-N 3.13Å; G390-G394 PolarHBondContact O-N 3.26Å
391	T	82.6	Confident	87.9	Confident	6 Å²	6	7.9 Å²	7.9	4%	0.037	4%	0.04	C	C	.	.	H	α-helix	trans	-66.5	-35.8	177.5	48.6	0	0	0	0	113.4	F196 T387 M388 Q395 V412	F196-T391 VanDerWaalsContact CE1-OG1 3.25Å; F196-T391 WeakPolarHBondContact CE1-OG1 3.36Å; T387-T391 WeakPolarHBondContact O-CG2 3.32Å; T387-T391 PolarHBondContact O-N 3.18Å; T387-T391 PolarHBondContact O-OG1 2.75Å; M388-T391 WeakPolarHBondContact CA-OG1 3.39Å; M388-T391 PolarHBondContact O-OG1 2.92Å; T391-Q395 PolarHBondContact O-N 3.48Å; T391-Q395 VanDerWaalsContact O-N 3.13Å; T391-V412 HydrophobicContact CG2-CG1 3.94Å; T391-V412 HydrophobicContact CG2-CG2 4.15Å
392	Y	82.4	Confident	87.5	Confident	8 Å²	8	9.9 Å²	9.9	3%	0.031	5%	0.049	C	C	.	.	H	α-helix	trans	-62.3	-42.8	167.6	-79.9	-57.3	0	0	0	112.7	Y50 F196 L207 F211 L271 M388 G390 Q395 F396	Y50-Y392 AromaticContact CD1-CE1 3.89Å; Y50-Y392 HydrophobicContact CD1-CE1 3.89Å; Y50-Y392 HydrophobicContact CD2-CD1 4.49Å; Y50-Y392 AromaticContact CD2-CE1 3.82Å; Y50-Y392 HydrophobicContact CD2-CE1 3.82Å; Y50-Y392 AromaticContact CE1-CE1 3.58Å; Y50-Y392 HydrophobicContact CE1-CE1 3.58Å; Y50-Y392 AromaticContact CE1-CZ 3.77Å; Y50-Y392 WeakPolarHBondContact CE1-OH 3.19Å; Y50-Y392 HydrophobicContact CE2-CD1 4.22Å; Y50-Y392 AromaticContact CE2-CE1 3.53Å; Y50-Y392 HydrophobicContact CE2-CE1 3.53Å; Y50-Y392 AromaticContact CG-CE1 3.99Å; Y50-Y392 HydrophobicContact CG-CE1 3.99Å; Y50-Y392 AromaticContact CZ-CE1 3.39Å; Y50-Y392 AromaticContact CZ-CZ 3.89Å; F196-Y392 HydrophobicContact CE2-CD2 4.48Å; F196-Y392 AromaticContact CE2-CE2 3.75Å; F196-Y392 HydrophobicContact CE2-CE2 3.75Å; F196-Y392 AromaticContact CE2-CZ 3.75Å; F196-Y392 HydrophobicContact CZ-CE1 4.26Å; F196-Y392 HydrophobicContact CZ-CE2 4.09Å; F196-Y392 AromaticContact CZ-CZ 3.92Å; L207-Y392 VanDerWaalsContact CD1-OH 3.31Å; L207-Y392 WeakPolarHBondContact CD1-OH 3.06Å; L207-Y392 HydrophobicContact CD2-CE2 4.05Å; L207-Y392 WeakPolarHBondContact CD2-OH 3.38Å; F211-Y392 HydrophobicContact CE2-CE2 4.3Å; F211-Y392 HydrophobicContact CZ-CE2 4.29Å; L271-Y392 HydrophobicContact CD1-CG 4.47Å; M388-Y392 WeakPolarHBondContact O-CD2 3.25Å; M388-Y392 PolarHBondContact O-N 2.99Å; G390-Y392 PolarHBondContact O-N 3.37Å; Y392-Q395 WeakPolarHBondContact O-CB 3.41Å; Y392-Q395 PolarHBondContact O-N 2.9Å; Y392-F396 HydrophobicContact CD1-CE2 4.33Å; Y392-F396 WeakPolarHBondContact O-CD2 3.38Å; Y392-F396 PolarHBondContact O-N 2.97Å; Y392-F396 VanDerWaalsContact O-N 3.11Å
393	S	88.4	Confident	87.1	Confident	0 Å²	0	15.1 Å²	15.1	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-62.2	-47.3	-180	-59.8	0	0	0	0	111.1	H267 T389 G390 Q395 F396 V397	H267-S393 PolarHBondContact CD2-OG 2.98Å; T389-S393 WeakPolarHBondContact O-CB 3.4Å; T389-S393 PolarHBondContact O-N 3.31Å; T389-S393 PolarHBondContact O-OG 3.38Å; G390-S393 WeakPolarHBondContact O-CB 3.32Å; G390-S393 PolarHBondContact O-N 3.24Å; G390-S393 VanDerWaalsContact O-N 3.13Å; S393-Q395 VanDerWaalsContact C-N 3.31Å; S393-Q395 PolarHBondContact O-N 2.93Å; S393-F396 PolarHBondContact O-N 3.48Å; S393-V397 VanDerWaalsContact O-CB 3.28Å; S393-V397 WeakPolarHBondContact O-CB 3.3Å; S393-V397 VanDerWaalsContact O-CG2 3.27Å; S393-V397 WeakPolarHBondContact O-CG2 3.38Å; S393-V397 PolarHBondContact O-N 3.34Å
394	G	87.6	Confident	86.4	Confident	1 Å²	1	18.8 Å²	18.8	1%	0.01	10%	0.096	C	C	.	.	H	α-helix	trans	-57.9	-40.7	174.4	0	0	0	0	0	112.6	G390 M398	G390-G394 PolarHBondContact O-N 3.26Å; G394-M398 WeakPolarHBondContact O-CB 3.29Å; G394-M398 VanDerWaalsContact O-CG 3.3Å; G394-M398 WeakPolarHBondContact O-CG 3.45Å; G394-M398 PolarHBondContact O-N 3.46Å
395	Q	85.2	Confident	85.4	Confident	11 Å²	11	24.5 Å²	24.5	5%	0.051	12%	0.12	C	C	.	.	H	α-helix	trans	-57	-57.9	173	166.5	151.6	11.5	0	0	112.3	T391 Y392 S393 V397 M398 E399	T391-Q395 PolarHBondContact O-N 3.48Å; T391-Q395 VanDerWaalsContact O-N 3.13Å; Y392-Q395 WeakPolarHBondContact O-CB 3.41Å; Y392-Q395 PolarHBondContact O-N 2.9Å; S393-Q395 VanDerWaalsContact C-N 3.31Å; S393-Q395 PolarHBondContact O-N 2.93Å; Q395-V397 VanDerWaalsContact C-N 3.28Å; Q395-V397 PolarHBondContact O-N 2.97Å; Q395-M398 PolarHBondContact O-N 3.25Å; Q395-E399 WeakPolarHBondContact CG-OE2 3.3Å; Q395-E399 PolarHBondContact NE2-OE1 2.96Å; Q395-E399 VanDerWaalsContact NE2-OE1 3.12Å; Q395-E399 PolarHBondContact NE2-OE2 3.4Å; Q395-E399 WeakPolarHBondContact O-CB 3.14Å; Q395-E399 PolarHBondContact O-N 3.49Å
396	F	87.5	Confident	84.4	Confident	9 Å²	9	28.5 Å²	28.5	4%	0.039	14%	0.135	C	C	.	.	H	α-helix	trans	-68.4	-28.2	-174.9	-61.4	-57	0	0	0	112.9	F51 H132 A134 L271 A274 Y392 S393 G400	F51-F396 AromaticContact CE2-CE1 3.67Å; F51-F396 HydrophobicContact CE2-CE1 3.67Å; F51-F396 AromaticContact CE2-CZ 3.7Å; F51-F396 HydrophobicContact CE2-CZ 3.7Å; F51-F396 HydrophobicContact CZ-CE1 4.11Å; F51-F396 AromaticContact CZ-CZ 3.64Å; F51-F396 HydrophobicContact CZ-CZ 3.64Å; H132-F396 PolarHBondContact CE1-O 2.94Å; H132-F396 AromaticContact NE2-CD1 3.79Å; A134-F396 WeakPolarHBondContact CB-O 3.48Å; L271-F396 HydrophobicContact CD1-CD2 4.17Å; L271-F396 HydrophobicContact CD1-CE2 4.14Å; A274-F396 HydrophobicContact CB-CB 4.01Å; A274-F396 HydrophobicContact CB-CD1 3.63Å; A274-F396 HydrophobicContact CB-CD2 3.45Å; A274-F396 VanDerWaalsContact CB-CD2 3.45Å; A274-F396 HydrophobicContact CB-CE1 3.92Å; A274-F396 HydrophobicContact CB-CE2 3.73Å; A274-F396 HydrophobicContact CB-CG 3.4Å; A274-F396 HydrophobicContact CB-CZ 3.97Å; Y392-F396 HydrophobicContact CD1-CE2 4.33Å; Y392-F396 WeakPolarHBondContact O-CD2 3.38Å; Y392-F396 PolarHBondContact O-N 2.97Å; Y392-F396 VanDerWaalsContact O-N 3.11Å; S393-F396 PolarHBondContact O-N 3.48Å; F396-G400 PolarHBondContact O-N 3.16Å
397	V	90.6	Very high	83.8	Confident	0 Å²	0	31.1 Å²	31.1	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-71.4	-52.8	174.9	166.1	0	0	0	0	110.7	V153 I157 Y270 S393 Q395 E399 G400 F401	V153-V397 HydrophobicContact CB-CG1 4.2Å; V153-V397 HydrophobicContact CG1-CB 4.39Å; V153-V397 HydrophobicContact CG1-CG1 3.88Å; V153-V397 HydrophobicContact CG1-CG2 3.6Å; I157-V397 HydrophobicContact CD1-CB 4.05Å; I157-V397 HydrophobicContact CD1-CG1 4.25Å; I157-V397 HydrophobicContact CD1-CG2 3.9Å; Y270-V397 HydrophobicContact CD1-CG2 4.23Å; Y270-V397 HydrophobicContact CD2-CG2 4.5Å; Y270-V397 HydrophobicContact CG-CG2 3.97Å; S393-V397 VanDerWaalsContact O-CB 3.28Å; S393-V397 WeakPolarHBondContact O-CB 3.3Å; S393-V397 VanDerWaalsContact O-CG2 3.27Å; S393-V397 WeakPolarHBondContact O-CG2 3.38Å; S393-V397 PolarHBondContact O-N 3.34Å; Q395-V397 VanDerWaalsContact C-N 3.28Å; Q395-V397 PolarHBondContact O-N 2.97Å; V397-E399 PolarHBondContact O-N 3.2Å; V397-G400 PolarHBondContact O-N 3.29Å; V397-F401 HydrophobicContact CB-CD2 4.46Å; V397-F401 HydrophobicContact CG1-CD2 3.88Å; V397-F401 HydrophobicContact CG1-CE2 4.24Å; V397-F401 WeakPolarHBondContact O-CB 3.39Å; V397-F401 WeakPolarHBondContact O-CD2 3.39Å; V397-F401 PolarHBondContact O-N 2.73Å
398	M	87.8	Confident	83.1	Confident	15 Å²	15	33.4 Å²	33.4	7%	0.074	16%	0.162	C	C	.	.	H	α-helix	trans	-61.2	-46.8	176.7	-68.5	-169.9	94.8	0	0	112.8	W150 E154 G394 Q395 L402 W406 R411	W150-M398 HydrophobicContact CZ2-CE 4.42Å; E154-M398 WeakPolarHBondContact OE2-CG 3.38Å; G394-M398 WeakPolarHBondContact O-CB 3.29Å; G394-M398 VanDerWaalsContact O-CG 3.3Å; G394-M398 WeakPolarHBondContact O-CG 3.45Å; G394-M398 PolarHBondContact O-N 3.46Å; Q395-M398 PolarHBondContact O-N 3.25Å; M398-L402 WeakPolarHBondContact O-CB 3.32Å; M398-L402 PolarHBondContact O-N 2.75Å; M398-W406 HydrophobicContact CE-CE3 4.02Å; M398-W406 HydrophobicContact CE-CZ3 4.04Å; M398-W406 HydrophobicContact SD-CE3 4.18Å; M398-W406 HydrophobicContact SD-CZ3 4.35Å; M398-R411 HydrophobicContact SD-CG 3.75Å; M398-R411 PolarHBondContact SD-NE 2.93Å; M398-R411 VanDerWaalsContact SD-NE 3.36Å
399	E	86.8	Confident	82.7	Confident	44 Å²	44	38.1 Å²	38.1	21%	0.206	18%	0.182	C	C	.	.	H	α-helix	trans	-67.1	-40.8	-179.3	-83.8	157.4	-151	0	0	111.8	Q395 V397 N403 R411	Q395-E399 WeakPolarHBondContact CG-OE2 3.3Å; Q395-E399 PolarHBondContact NE2-OE1 2.96Å; Q395-E399 VanDerWaalsContact NE2-OE1 3.12Å; Q395-E399 PolarHBondContact NE2-OE2 3.4Å; Q395-E399 WeakPolarHBondContact O-CB 3.14Å; Q395-E399 PolarHBondContact O-N 3.49Å; V397-E399 PolarHBondContact O-N 3.2Å; E399-N403 WeakPolarHBondContact O-CA 3.35Å; E399-N403 PolarHBondContact O-N 2.99Å; E399-N403 VanDerWaalsContact O-N 3.11Å; E399-R411 IonicContact OE1-CZ 3.19Å; E399-R411 IonicContact OE1-NH1 2.74Å; E399-R411 PolarHBondContact OE1-NH1 2.76Å; E399-R411 IonicContact OE1-NH2 2.74Å; E399-R411 PolarHBondContact OE1-NH2 3.39Å
400	G	88.2	Confident	82.4	Confident	3 Å²	3	39.7 Å²	39.7	3%	0.031	20%	0.195	C	C	.	.	H	α-helix	trans	-67.6	-59.4	175.5	0	0	0	0	0	112.5	A134 H138 F396 V397	A134-G400 CarbonylContact O-C 3.58Å; H138-G400 WeakPolarHBondContact CB-O 3.06Å; H138-G400 PolarHBondContact ND1-O 3.01Å; F396-G400 PolarHBondContact O-N 3.16Å; V397-G400 PolarHBondContact O-N 3.29Å
401	F	90.4	Very high	82.1	Confident	0 Å²	0	39.8 Å²	39.8	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-70.6	-37.5	-171	-80.9	-82.1	0	0	0	114.2	A134 C137 H138 R146 L149 W150 Y270 V397	A134-F401 HydrophobicContact CB-CD2 3.49Å; A134-F401 VanDerWaalsContact CB-CD2 3.49Å; A134-F401 HydrophobicContact CB-CE2 3.61Å; A134-F401 HydrophobicContact CB-CG 4.3Å; A134-F401 HydrophobicContact CB-CZ 4.48Å; C137-F401 HydrophobicContact CB-CD1 4.11Å; C137-F401 HydrophobicContact CB-CE1 3.46Å; C137-F401 VanDerWaalsContact CB-CE1 3.46Å; C137-F401 HydrophobicContact CB-CZ 3.84Å; H138-F401 PolarHBondContact ND1-O 2.77Å; R146-F401 HydrophobicContact CG-CD1 3.91Å; R146-F401 PolarHBondContact NE-O 3.36Å; L149-F401 HydrophobicContact CB-CE1 4Å; L149-F401 HydrophobicContact CD2-CE1 3.77Å; L149-F401 HydrophobicContact CD2-CZ 4.02Å; L149-F401 HydrophobicContact CG-CE1 3.63Å; L149-F401 HydrophobicContact CG-CZ 3.75Å; W150-F401 HydrophobicContact CB-CB 3.71Å; W150-F401 HydrophobicContact CB-CD1 4Å; W150-F401 HydrophobicContact CB-CD2 4.35Å; W150-F401 HydrophobicContact CB-CG 3.8Å; W150-F401 HydrophobicContact CG-CB 3.93Å; W150-F401 HydrophobicContact CG-CG 4.36Å; Y270-F401 HydrophobicContact CD1-CE2 4.11Å; Y270-F401 AromaticContact CE1-CE2 3.55Å; Y270-F401 HydrophobicContact CE1-CE2 3.55Å; Y270-F401 AromaticContact CE1-CZ 3.71Å; Y270-F401 HydrophobicContact CE1-CZ 3.71Å; V397-F401 HydrophobicContact CB-CD2 4.46Å; V397-F401 HydrophobicContact CG1-CD2 3.88Å; V397-F401 HydrophobicContact CG1-CE2 4.24Å; V397-F401 WeakPolarHBondContact O-CB 3.39Å; V397-F401 WeakPolarHBondContact O-CD2 3.39Å; V397-F401 PolarHBondContact O-N 2.73Å
402	L	86.6	Confident	81.8	Confident	48 Å²	48	40 Å²	40	25%	0.251	20%	0.197	S	C	.	.	H	α-helix	trans	-104.2	-15.9	-175.3	-54.4	178.4	0	0	0	113.4	W150 M398 L404	W150-L402 HydrophobicContact CD2-CD1 3.86Å; W150-L402 HydrophobicContact CD2-CD2 4Å; W150-L402 HydrophobicContact CD2-CG 4.07Å; W150-L402 HydrophobicContact CE3-CD1 4.19Å; W150-L402 HydrophobicContact CE3-CD2 4.1Å; W150-L402 HydrophobicContact CG-CD1 4.47Å; W150-L402 HydrophobicContact CG-CD2 4.18Å; W150-L402 HydrophobicContact CG-CG 4.22Å; W150-L402 HydrophobicContact CH2-CD1 4.14Å; W150-L402 HydrophobicContact CZ2-CD1 3.81Å; W150-L402 HydrophobicContact CZ3-CD1 4.31Å; M398-L402 WeakPolarHBondContact O-CB 3.32Å; M398-L402 PolarHBondContact O-N 2.75Å; L402-L404 HydrophobicContact CB-CB 3.85Å; L402-L404 HydrophobicContact CD1-CD1 4.46Å; L402-L404 PolarHBondContact O-N 3.32Å
403	N	84.3	Confident	81.8	Confident	111 Å²	111	42.5 Å²	42.5	59%	0.594	21%	0.21	S	C	*	.			trans	54.9	32.4	-167.8	-163.7	13.5	0	0	0	112.2	E399 K405	E399-N403 WeakPolarHBondContact O-CA 3.35Å; E399-N403 PolarHBondContact O-N 2.99Å; E399-N403 VanDerWaalsContact O-N 3.11Å; N403-K405 PolarHBondContact O-N 3.08Å
404	L	77.8	Confident	81.6	Confident	77 Å²	77	46.3 Å²	46.3	40%	0.403	23%	0.23	S	C	.	.			trans	-96.7	97	-173.4	-162.1	161.9	0	0	0	109.6	L402 W406 R411	L402-L404 HydrophobicContact CB-CB 3.85Å; L402-L404 HydrophobicContact CD1-CD1 4.46Å; L402-L404 PolarHBondContact O-N 3.32Å; L404-W406 HydrophobicContact CD2-CB 3.85Å; L404-W406 HydrophobicContact CD2-CG 4.31Å; L404-W406 PolarHBondContact O-N 3.27Å; L404-R411 PolarHBondContact O-NH2 3.43Å
405	K	68.9	Low	81.2	Confident	171 Å²	171	46.7 Å²	46.7	74%	0.743	23%	0.232	S	C	*	.			trans	-71.9	106.7	175.8	-62.5	-174.3	179.1	-173.6	0	109.6	N403	N403-K405 PolarHBondContact O-N 3.08Å
406	W	70	Confident	81.2	Confident	84 Å²	84	46.4 Å²	46.4	32%	0.318	23%	0.231	S	C	.	.			trans	-121.4	158.4	-178.4	-158.9	16.9	0	0	0	111.1	M398 L404 R408 A410 R411 L414	M398-W406 HydrophobicContact CE-CE3 4.02Å; M398-W406 HydrophobicContact CE-CZ3 4.04Å; M398-W406 HydrophobicContact SD-CE3 4.18Å; M398-W406 HydrophobicContact SD-CZ3 4.35Å; L404-W406 HydrophobicContact CD2-CB 3.85Å; L404-W406 HydrophobicContact CD2-CG 4.31Å; L404-W406 PolarHBondContact O-N 3.27Å; W406-R408 PolarHBondContact O-N 3.43Å; W406-A410 HydrophobicContact CD2-CB 4.4Å; W406-A410 HydrophobicContact CZ2-CB 3.8Å; W406-R411 HydrophobicContact CD2-CB 4.2Å; W406-R411 HydrophobicContact CE3-CB 3.62Å; W406-R411 HydrophobicContact CE3-CG 4.09Å; W406-R411 HydrophobicContact CZ3-CB 4.01Å; W406-R411 HydrophobicContact CZ3-CG 4.31Å; W406-L414 HydrophobicContact CH2-CB 3.65Å; W406-L414 HydrophobicContact CH2-CD2 3.59Å; W406-L414 HydrophobicContact CH2-CG 4.14Å; W406-L414 HydrophobicContact CZ3-CB 4.18Å; W406-L414 HydrophobicContact CZ3-CD2 3.85Å
407	S	73.8	Confident	81.1	Confident	55 Å²	55	48.4 Å²	48.4	39%	0.385	25%	0.246	S	C	.	.			trans	-67.7	131.5	172.9	173.7	0	0	0	0	109.7	F409 A410 R411	S407-F409 VanDerWaalsContact C-N 3.26Å; S407-F409 PolarHBondContact O-N 2.79Å; S407-A410 PolarHBondContact O-N 3.03Å; S407-A410 VanDerWaalsContact O-N 3.08Å; S407-R411 PolarHBondContact O-N 3.41Å
408	R	70.9	Confident	81	Confident	52 Å²	52	52.1 Å²	52.1	20%	0.196	27%	0.265	C	S	.	.	H	α-helix	trans	-48.9	-48.7	177.3	-74.9	178.8	-96.5	-161.9	-10.9	111.7	A48 D200 W406 A410 R411 V412	A48-R408 PolarHBondContact O-NH2 2.96Å; D200-R408 IonicContact OD1-NH1 2.86Å; D200-R408 PolarHBondContact OD1-NH1 2.71Å; D200-R408 VanDerWaalsContact OD2-CD 3.25Å; D200-R408 WeakPolarHBondContact OD2-CD 3.47Å; D200-R408 IonicContact OD2-CZ 3.48Å; D200-R408 IonicContact OD2-NE 3.61Å; D200-R408 IonicContact OD2-NH1 2.77Å; D200-R408 PolarHBondContact OD2-NH1 3.36Å; W406-R408 PolarHBondContact O-N 3.43Å; R408-A410 PolarHBondContact O-N 2.99Å; R408-R411 PolarHBondContact O-N 2.94Å; R408-V412 WeakPolarHBondContact O-CB 3.48Å; R408-V412 VanDerWaalsContact O-CG2 3.27Å; R408-V412 WeakPolarHBondContact O-CG2 3.35Å; R408-V412 PolarHBondContact O-N 2.78Å
409	F	75.7	Confident	80.8	Confident	105 Å²	105	51.4 Å²	51.4	46%	0.461	26%	0.261	S	S	.	.	H	α-helix	trans	-56.4	-47.2	179.1	-169.6	-101.4	0	0	0	112.4	F194 L197 S407 I413	F194-F409 HydrophobicContact CD1-CE2 4.47Å; F194-F409 AromaticContact CE1-CE2 3.99Å; F194-F409 HydrophobicContact CE1-CE2 3.99Å; F194-F409 HydrophobicContact CE1-CZ 4.2Å; L197-F409 HydrophobicContact CD1-CD2 3.66Å; L197-F409 HydrophobicContact CD1-CE2 4.03Å; S407-F409 VanDerWaalsContact C-N 3.26Å; S407-F409 PolarHBondContact O-N 2.79Å; F409-I413 HydrophobicContact CD1-CD1 3.73Å; F409-I413 HydrophobicContact CD2-CD1 4.32Å; F409-I413 HydrophobicContact CE1-CD1 3.34Å; F409-I413 HydrophobicContact CE2-CD1 3.97Å; F409-I413 HydrophobicContact CG-CD1 4.21Å; F409-I413 HydrophobicContact CZ-CD1 3.46Å; F409-I413 VanDerWaalsContact CZ-CD1 3.46Å; F409-I413 WeakPolarHBondContact O-CB 3.36Å; F409-I413 VanDerWaalsContact O-CG1 3.32Å; F409-I413 WeakPolarHBondContact O-CG1 3.37Å; F409-I413 PolarHBondContact O-N 3.1Å
410	A	80.2	Confident	80.9	Confident	33 Å²	33	49.8 Å²	49.8	27%	0.273	25%	0.254	S	S	.	.	H	α-helix	trans	-71	-38.5	-178.3	0	0	0	0	0	112.7	W406 S407 R408 L414	W406-A410 HydrophobicContact CD2-CB 4.4Å; W406-A410 HydrophobicContact CZ2-CB 3.8Å; S407-A410 PolarHBondContact O-N 3.03Å; S407-A410 VanDerWaalsContact O-N 3.08Å; R408-A410 PolarHBondContact O-N 2.99Å; A410-L414 PolarHBondContact O-N 3.28Å; A410-L414 VanDerWaalsContact O-N 3.09Å
411	R	77.8	Confident	80.9	Confident	3 Å²	3	54.4 Å²	54.4	1%	0.011	28%	0.277	C	S	.	.	H	α-helix	trans	-61.5	-55.4	174.1	179.7	-176.9	-64.9	130.3	-1.4	111.3	M398 E399 L404 W406 S407 R408 I413 L414 T415	M398-R411 HydrophobicContact SD-CG 3.75Å; M398-R411 PolarHBondContact SD-NE 2.93Å; M398-R411 VanDerWaalsContact SD-NE 3.36Å; E399-R411 IonicContact OE1-CZ 3.19Å; E399-R411 IonicContact OE1-NH1 2.74Å; E399-R411 PolarHBondContact OE1-NH1 2.76Å; E399-R411 IonicContact OE1-NH2 2.74Å; E399-R411 PolarHBondContact OE1-NH2 3.39Å; L404-R411 PolarHBondContact O-NH2 3.43Å; W406-R411 HydrophobicContact CD2-CB 4.2Å; W406-R411 HydrophobicContact CE3-CB 3.62Å; W406-R411 HydrophobicContact CE3-CG 4.09Å; W406-R411 HydrophobicContact CZ3-CB 4.01Å; W406-R411 HydrophobicContact CZ3-CG 4.31Å; S407-R411 PolarHBondContact O-N 3.41Å; R408-R411 PolarHBondContact O-N 2.94Å; R411-I413 VanDerWaalsContact C-N 3.31Å; R411-I413 PolarHBondContact O-N 2.78Å; R411-L414 PolarHBondContact O-N 3.48Å; R411-T415 PolarHBondContact O-N 3Å
412	V	77.8	Confident	80.6	Confident	9 Å²	9	56.5 Å²	56.5	6%	0.055	29%	0.29	C	S	.	.	H	α-helix	trans	-62.1	-40.3	-174.7	170.6	0	0	0	0	110.9	T193 F196 T391 R408 T415 R416	T193-V412 HydrophobicContact CG2-CG1 3.42Å; T193-V412 VanDerWaalsContact CG2-CG1 3.42Å; F196-V412 HydrophobicContact CE1-CG2 4.32Å; T391-V412 HydrophobicContact CG2-CG1 3.94Å; T391-V412 HydrophobicContact CG2-CG2 4.15Å; R408-V412 WeakPolarHBondContact O-CB 3.48Å; R408-V412 VanDerWaalsContact O-CG2 3.27Å; R408-V412 WeakPolarHBondContact O-CG2 3.35Å; R408-V412 PolarHBondContact O-N 2.78Å; V412-T415 PolarHBondContact O-OG1 3.16Å; V412-R416 HydrophobicContact CG1-CG 4.38Å; V412-R416 VanDerWaalsContact O-CB 3.28Å; V412-R416 WeakPolarHBondContact O-CB 3.39Å; V412-R416 VanDerWaalsContact O-CG 3.29Å; V412-R416 WeakPolarHBondContact O-CG 3.36Å; V412-R416 PolarHBondContact O-N 3.14Å
413	I	82.3	Confident	80.5	Confident	62 Å²	62	54.2 Å²	54.2	32%	0.318	28%	0.278	S	S	.	.	H	α-helix	trans	-64.8	-38.5	173.8	-73	175	0	0	0	111.8	F409 R411 S417	F409-I413 HydrophobicContact CD1-CD1 3.73Å; F409-I413 HydrophobicContact CD2-CD1 4.32Å; F409-I413 HydrophobicContact CE1-CD1 3.34Å; F409-I413 HydrophobicContact CE2-CD1 3.97Å; F409-I413 HydrophobicContact CG-CD1 4.21Å; F409-I413 HydrophobicContact CZ-CD1 3.46Å; F409-I413 VanDerWaalsContact CZ-CD1 3.46Å; F409-I413 WeakPolarHBondContact O-CB 3.36Å; F409-I413 VanDerWaalsContact O-CG1 3.32Å; F409-I413 WeakPolarHBondContact O-CG1 3.37Å; F409-I413 PolarHBondContact O-N 3.1Å; R411-I413 VanDerWaalsContact C-N 3.31Å; R411-I413 PolarHBondContact O-N 2.78Å; I413-S417 WeakPolarHBondContact O-CB 3.37Å; I413-S417 PolarHBondContact O-N 2.79Å; I413-S417 PolarHBondContact O-OG 2.98Å
414	L	84.2	Confident	80.7	Confident	80 Å²	80	51 Å²	51	42%	0.419	26%	0.261	S	S	.	.	H	α-helix	trans	-64.8	-51.8	176.6	-174.9	77.1	0	0	0	111.4	W406 A410 R411 S417 I418	W406-L414 HydrophobicContact CH2-CB 3.65Å; W406-L414 HydrophobicContact CH2-CD2 3.59Å; W406-L414 HydrophobicContact CH2-CG 4.14Å; W406-L414 HydrophobicContact CZ3-CB 4.18Å; W406-L414 HydrophobicContact CZ3-CD2 3.85Å; A410-L414 PolarHBondContact O-N 3.28Å; A410-L414 VanDerWaalsContact O-N 3.09Å; R411-L414 PolarHBondContact O-N 3.48Å; L414-S417 PolarHBondContact O-N 3.25Å; L414-I418 HydrophobicContact CD1-CD1 4.13Å; L414-I418 HydrophobicContact CD2-CD1 4.11Å; L414-I418 HydrophobicContact CG-CD1 3.77Å; L414-I418 HydrophobicContact CG-CG1 4.44Å; L414-I418 WeakPolarHBondContact O-CG1 3.34Å; L414-I418 PolarHBondContact O-N 3.3Å
415	T	78.4	Confident	81	Confident	8 Å²	8	51.8 Å²	51.8	5%	0.049	27%	0.265	C	S	.	.	H	α-helix	trans	-63	-46.7	-176.2	58.6	0	0	0	0	111.1	R411 V412 S417 I418 A419	R411-T415 PolarHBondContact O-N 3Å; V412-T415 PolarHBondContact O-OG1 3.16Å; T415-S417 VanDerWaalsContact C-N 3.33Å; T415-S417 PolarHBondContact O-N 2.84Å; T415-I418 PolarHBondContact O-N 2.94Å; T415-I418 VanDerWaalsContact O-N 3.17Å; T415-A419 PolarHBondContact O-N 3.06Å; T415-A419 VanDerWaalsContact O-N 3.12Å
416	R	84.3	Confident	81.6	Confident	6 Å²	6	45.2 Å²	45.2	2%	0.023	24%	0.24	C	C	.	.	H	α-helix	trans	-60.5	-40.2	174	-70.7	-75.4	121.9	158.2	-0.6	111.7	D161 E164 T193 T387 V412 I418 A419 I420	D161-R416 IonicContact OD1-CZ 2.77Å; D161-R416 IonicContact OD1-NE 3.72Å; D161-R416 PolarHBondContact OD1-NE 3.27Å; D161-R416 IonicContact OD1-NH1 3.12Å; D161-R416 IonicContact OD1-NH2 2.76Å; D161-R416 PolarHBondContact OD1-NH2 2.97Å; D161-R416 IonicContact OD2-CZ 3.59Å; D161-R416 IonicContact OD2-NE 3.04Å; D161-R416 PolarHBondContact OD2-NE 3.23Å; D161-R416 IonicContact OD2-NH2 2.73Å; D161-R416 PolarHBondContact OD2-NH2 2.87Å; E164-R416 IonicContact OE2-CZ 3.75Å; E164-R416 IonicContact OE2-NH1 2.81Å; E164-R416 IonicContact OE2-NH2 2.88Å; E164-R416 PolarHBondContact OE2-NH2 3.45Å; T193-R416 HydrophobicContact CG2-CG 4.14Å; T387-R416 PolarHBondContact OG1-NH1 3.42Å; V412-R416 HydrophobicContact CG1-CG 4.38Å; V412-R416 VanDerWaalsContact O-CB 3.28Å; V412-R416 WeakPolarHBondContact O-CB 3.39Å; V412-R416 VanDerWaalsContact O-CG 3.29Å; V412-R416 WeakPolarHBondContact O-CG 3.36Å; V412-R416 PolarHBondContact O-N 3.14Å; R416-I418 PolarHBondContact O-N 2.89Å; R416-A419 PolarHBondContact O-N 3.32Å; R416-I420 HydrophobicContact CB-CD1 4.16Å; R416-I420 WeakPolarHBondContact O-CB 3.42Å; R416-I420 WeakPolarHBondContact O-CG1 3.21Å; R416-I420 PolarHBondContact O-N 2.85Å
417	S	87	Confident	82.1	Confident	51 Å²	51	41.8 Å²	41.8	36%	0.357	23%	0.229	S	C	.	.	H	α-helix	trans	-62.4	-41.9	175.6	-63.3	0	0	0	0	112.2	I413 L414 T415 A419 I421	I413-S417 WeakPolarHBondContact O-CB 3.37Å; I413-S417 PolarHBondContact O-N 2.79Å; I413-S417 PolarHBondContact O-OG 2.98Å; L414-S417 PolarHBondContact O-N 3.25Å; T415-S417 VanDerWaalsContact C-N 3.33Å; T415-S417 PolarHBondContact O-N 2.84Å; S417-A419 VanDerWaalsContact C-N 3.31Å; S417-A419 PolarHBondContact O-N 3.34Å; S417-I421 WeakPolarHBondContact O-CB 3.26Å; S417-I421 WeakPolarHBondContact O-CD1 3.44Å; S417-I421 WeakPolarHBondContact O-CG1 3.41Å; S417-I421 PolarHBondContact O-N 3.43Å
418	I	87	Confident	82.5	Confident	77 Å²	77	43 Å²	43	40%	0.395	23%	0.234	S	C	.	.	H	α-helix	trans	-66.6	-32	-179.3	-68.4	169.5	0	0	0	111.9	I158 L414 T415 R416 P422	I158-I418 HydrophobicContact CD1-CG2 3.86Å; I158-I418 HydrophobicContact CG1-CG2 4.22Å; I158-I418 HydrophobicContact CG2-CG2 3.95Å; L414-I418 HydrophobicContact CD1-CD1 4.13Å; L414-I418 HydrophobicContact CD2-CD1 4.11Å; L414-I418 HydrophobicContact CG-CD1 3.77Å; L414-I418 HydrophobicContact CG-CG1 4.44Å; L414-I418 WeakPolarHBondContact O-CG1 3.34Å; L414-I418 PolarHBondContact O-N 3.3Å; T415-I418 PolarHBondContact O-N 2.94Å; T415-I418 VanDerWaalsContact O-N 3.17Å; R416-I418 PolarHBondContact O-N 2.89Å; I418-P422 WeakPolarHBondContact O-CD 3.33Å; I418-P422 VanDerWaalsContact O-CG 3.28Å; I418-P422 WeakPolarHBondContact O-CG 3.49Å
419	A	84.6	Confident	82.7	Confident	0 Å²	0	47.7 Å²	47.7	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-85.9	-38.9	175.8	0	0	0	0	0	113.8	D161 M162 T415 R416 S417 P422 T423	D161-A419 HydrophobicContact CB-CB 3.63Å; D161-A419 VanDerWaalsContact CG-CB 3.42Å; D161-A419 WeakPolarHBondContact OD1-CB 3.25Å; M162-A419 HydrophobicContact CG-CB 3.74Å; T415-A419 PolarHBondContact O-N 3.06Å; T415-A419 VanDerWaalsContact O-N 3.12Å; R416-A419 PolarHBondContact O-N 3.32Å; S417-A419 VanDerWaalsContact C-N 3.31Å; S417-A419 PolarHBondContact O-N 3.34Å; A419-P422 WeakPolarHBondContact O-CD 3.29Å; A419-P422 WeakPolarHBondContact O-CG 3.25Å; A419-T423 WeakPolarHBondContact O-CB 3.37Å; A419-T423 PolarHBondContact O-N 3.41Å; A419-T423 PolarHBondContact O-OG1 3Å
420	I	88.3	Confident	82.1	Confident	11 Å²	11	47.5 Å²	47.5	6%	0.056	26%	0.256	C	S	.	.	H	α-helix	trans	-71.2	-37.6	-179	-69	172.9	0	0	0	111.3	V165 V186 I190 R416 T423 L424	V165-I420 HydrophobicContact CG1-CG1 4.25Å; V165-I420 HydrophobicContact CG2-CD1 4.49Å; V165-I420 HydrophobicContact CG2-CG1 3.9Å; V186-I420 HydrophobicContact CG1-CG2 3.91Å; I190-I420 HydrophobicContact CD1-CG2 4.49Å; I190-I420 HydrophobicContact CG1-CD1 3.78Å; I190-I420 HydrophobicContact CG1-CG2 4.49Å; R416-I420 HydrophobicContact CB-CD1 4.16Å; R416-I420 WeakPolarHBondContact O-CB 3.42Å; R416-I420 WeakPolarHBondContact O-CG1 3.21Å; R416-I420 PolarHBondContact O-N 2.85Å; I420-T423 PolarHBondContact O-N 3.43Å; I420-L424 WeakPolarHBondContact O-CB 3.41Å; I420-L424 PolarHBondContact O-N 2.71Å
421	I	89.6	Confident	81.3	Confident	100 Å²	100	52 Å²	52	51%	0.513	28%	0.276	S	S	.	.	H	α-helix	trans	-57.1	-56	179.1	-72.4	166.6	0	0	0	113.2	S417 T423 L424 L425	S417-I421 WeakPolarHBondContact O-CB 3.26Å; S417-I421 WeakPolarHBondContact O-CD1 3.44Å; S417-I421 WeakPolarHBondContact O-CG1 3.41Å; S417-I421 PolarHBondContact O-N 3.43Å; I421-T423 VanDerWaalsContact C-N 3.34Å; I421-T423 PolarHBondContact O-N 3.25Å; I421-L424 PolarHBondContact O-N 3.05Å; I421-L425 HydrophobicContact CG2-CD1 4.01Å; I421-L425 VanDerWaalsContact O-CG 3.27Å; I421-L425 WeakPolarHBondContact O-CG 3.26Å; I421-L425 PolarHBondContact O-N 3.46Å
422	P	83.8	Confident	80.4	Confident	43 Å²	43	53.7 Å²	53.7	28%	0.279	29%	0.287	S	S	.	.	H	α-helix	trans	-63.5	-40.2	178.4	24.5	-33	0	0	0	111.6	M162 I418 A419 L424 L425 V426	M162-P422 HydrophobicContact CE-CB 4.11Å; M162-P422 HydrophobicContact CE-CG 3.93Å; M162-P422 HydrophobicContact SD-CG 3.96Å; I418-P422 WeakPolarHBondContact O-CD 3.33Å; I418-P422 VanDerWaalsContact O-CG 3.28Å; I418-P422 WeakPolarHBondContact O-CG 3.49Å; A419-P422 WeakPolarHBondContact O-CD 3.29Å; A419-P422 WeakPolarHBondContact O-CG 3.25Å; P422-L424 VanDerWaalsContact C-N 3.35Å; P422-L424 PolarHBondContact O-N 3.41Å; P422-L425 PolarHBondContact O-N 2.92Å; P422-V426 WeakPolarHBondContact O-CG2 3.04Å; P422-V426 PolarHBondContact O-N 3.12Å
423	T	84.1	Confident	79.6	Confident	0 Å²	0	58.6 Å²	58.6	0%	0	31%	0.309	C	S	.	.	H	α-helix	trans	-63.6	-40.1	179.4	-50.6	0	0	0	0	111.9	V165 I166 V186 A419 I420 I421 A427 L435 M438	V165-T423 HydrophobicContact CG1-CG2 3.91Å; I166-T423 HydrophobicContact CG1-CG2 3.77Å; V186-T423 HydrophobicContact CG1-CG2 4.45Å; V186-T423 HydrophobicContact CG2-CG2 4.04Å; A419-T423 WeakPolarHBondContact O-CB 3.37Å; A419-T423 PolarHBondContact O-N 3.41Å; A419-T423 PolarHBondContact O-OG1 3Å; I420-T423 PolarHBondContact O-N 3.43Å; I421-T423 VanDerWaalsContact C-N 3.34Å; I421-T423 PolarHBondContact O-N 3.25Å; T423-A427 VanDerWaalsContact O-CB 3.25Å; T423-A427 WeakPolarHBondContact O-CB 3.34Å; T423-A427 PolarHBondContact O-N 3.13Å; T423-L435 HydrophobicContact CG2-CD2 4.39Å; T423-M438 HydrophobicContact CG2-CE 4.09Å
424	L	87.8	Confident	78.6	Confident	45 Å²	45	60.3 Å²	60.3	24%	0.236	32%	0.315	C	S	.	.	H	α-helix	trans	-69.1	-39.4	175.3	-176.8	64.5	0	0	0	111.8	W183 V186 L187 I420 I421 P422 A427 V428	W183-L424 HydrophobicContact CB-CD1 3.85Å; V186-L424 HydrophobicContact CB-CD1 4.4Å; V186-L424 HydrophobicContact CG1-CB 3.89Å; V186-L424 HydrophobicContact CG1-CD1 4.11Å; L187-L424 HydrophobicContact CD2-CD1 4.3Å; L187-L424 HydrophobicContact CD2-CD2 3.96Å; L187-L424 HydrophobicContact CG-CD1 4.2Å; I420-L424 WeakPolarHBondContact O-CB 3.41Å; I420-L424 PolarHBondContact O-N 2.71Å; I421-L424 PolarHBondContact O-N 3.05Å; P422-L424 VanDerWaalsContact C-N 3.35Å; P422-L424 PolarHBondContact O-N 3.41Å; L424-A427 PolarHBondContact O-N 3.49Å; L424-V428 HydrophobicContact CD1-CG2 4.08Å; L424-V428 HydrophobicContact CG-CG2 4.38Å; L424-V428 WeakPolarHBondContact O-CB 3.19Å; L424-V428 VanDerWaalsContact O-CG2 3.25Å; L424-V428 WeakPolarHBondContact O-CG2 3.22Å; L424-V428 PolarHBondContact O-N 3.4Å
425	L	85.1	Confident	77.6	Confident	92 Å²	92	56.8 Å²	56.8	48%	0.482	30%	0.297	S	S	.	.	H	α-helix	trans	-61.6	-46.6	175.1	-72.8	170	0	0	0	111.1	I421 P422 V428 F429	I421-L425 HydrophobicContact CG2-CD1 4.01Å; I421-L425 VanDerWaalsContact O-CG 3.27Å; I421-L425 WeakPolarHBondContact O-CG 3.26Å; I421-L425 PolarHBondContact O-N 3.46Å; P422-L425 PolarHBondContact O-N 2.92Å; L425-V428 PolarHBondContact O-N 2.93Å; L425-F429 HydrophobicContact CD2-CD2 4.12Å; L425-F429 HydrophobicContact CD2-CE2 3.77Å; L425-F429 WeakPolarHBondContact O-CB 3.38Å; L425-F429 WeakPolarHBondContact O-CD2 3.38Å; L425-F429 PolarHBondContact O-N 2.8Å
426	V	80.5	Confident	76.9	Confident	34 Å²	34	56.8 Å²	56.8	21%	0.206	30%	0.297	C	S	.	.	H	α-helix	trans	-62.2	-46.2	174.4	-179.4	0	0	0	0	110.3	P422 V428 F429 Q430 H434 L435 M438	P422-V426 WeakPolarHBondContact O-CG2 3.04Å; P422-V426 PolarHBondContact O-N 3.12Å; V426-V428 PolarHBondContact O-N 2.74Å; V426-V428 VanDerWaalsContact O-N 3.16Å; V426-F429 PolarHBondContact O-N 3.17Å; V426-Q430 HydrophobicContact CG1-CB 4.1Å; V426-Q430 HydrophobicContact CG1-CG 4.39Å; V426-Q430 WeakPolarHBondContact O-CA 3.36Å; V426-Q430 WeakPolarHBondContact O-CB 3.49Å; V426-Q430 PolarHBondContact O-N 2.93Å; V426-H434 HydrophobicContact CG1-CB 4.16Å; V426-L435 HydrophobicContact CB-CD2 3.84Å; V426-L435 HydrophobicContact CG1-CD2 3.58Å; V426-L435 HydrophobicContact CG1-CG 3.9Å; V426-M438 HydrophobicContact CB-CE 4.42Å; V426-M438 HydrophobicContact CG2-CE 4.42Å; V426-M438 HydrophobicContact CG2-SD 4.05Å
427	A	80.3	Confident	76.1	Confident	12 Å²	12	58.3 Å²	58.3	10%	0.099	32%	0.315	C	S	.	.	H	α-helix	trans	-68.5	-11.1	-179.4	0	0	0	0	0	115.9	W183 V186 T423 L424 L435	W183-A427 HydrophobicContact CB-CB 4.09Å; V186-A427 HydrophobicContact CG2-CB 4.4Å; T423-A427 VanDerWaalsContact O-CB 3.25Å; T423-A427 WeakPolarHBondContact O-CB 3.34Å; T423-A427 PolarHBondContact O-N 3.13Å; L424-A427 PolarHBondContact O-N 3.49Å; A427-L435 HydrophobicContact CB-CD1 3.87Å; A427-L435 HydrophobicContact CB-CD2 4.14Å
428	V	81.9	Confident	75.5	Confident	79 Å²	79	57.1 Å²	57.1	48%	0.479	30%	0.304	S	S	.	.	H	α-helix	trans	-104	-34.8	176.2	168.7	0	0	0	0	112	W183 L424 L425 V426	W183-V428 HydrophobicContact CB-CG2 3.65Å; W183-V428 HydrophobicContact CG-CG2 4.07Å; L424-V428 HydrophobicContact CD1-CG2 4.08Å; L424-V428 HydrophobicContact CG-CG2 4.38Å; L424-V428 WeakPolarHBondContact O-CB 3.19Å; L424-V428 VanDerWaalsContact O-CG2 3.25Å; L424-V428 WeakPolarHBondContact O-CG2 3.22Å; L424-V428 PolarHBondContact O-N 3.4Å; L425-V428 PolarHBondContact O-N 2.93Å; V426-V428 PolarHBondContact O-N 2.74Å; V426-V428 VanDerWaalsContact O-N 3.16Å
429	F	75.4	Confident	75	Confident	151 Å²	151	53.5 Å²	53.5	66%	0.662	29%	0.285	S	S	*	.	H	α-helix	trans	-105.1	-10.7	-174.2	-68	-67.6	0	0	0	114.9	L425 V426	L425-F429 HydrophobicContact CD2-CD2 4.12Å; L425-F429 HydrophobicContact CD2-CE2 3.77Å; L425-F429 WeakPolarHBondContact O-CB 3.38Å; L425-F429 WeakPolarHBondContact O-CD2 3.38Å; L425-F429 PolarHBondContact O-N 2.8Å; V426-F429 PolarHBondContact O-N 3.17Å
430	Q	64.7	Low	74.5	Confident	101 Å²	101	56.3 Å²	56.3	47%	0.472	30%	0.3	S	S	.	.	S	Bend	trans	-134.6	153.7	-177.2	-55.8	-75.1	-103.5	0	0	111.7	V426 H434	V426-Q430 HydrophobicContact CG1-CB 4.1Å; V426-Q430 HydrophobicContact CG1-CG 4.39Å; V426-Q430 WeakPolarHBondContact O-CA 3.36Å; V426-Q430 WeakPolarHBondContact O-CB 3.49Å; V426-Q430 PolarHBondContact O-N 2.93Å; Q430-H434 HydrophobicContact CB-CB 3.75Å; Q430-H434 HydrophobicContact CG-CB 4.39Å
431	D	63.4	Low	74	Confident	127 Å²	127	60.8 Å²	60.8	68%	0.679	32%	0.319	S	S	*	.			trans	-73.6	164.5	177.5	-65.4	-69.1	0	0	0	113.3	E433 H434	D431-E433 PolarHBondContact O-N 3.05Å; D431-H434 WeakPolarHBondContact O-CB 3.45Å; D431-H434 PolarHBondContact O-N 2.92Å
432	V	58.8	Low	73.7	Confident	40 Å²	40	56.3 Å²	56.3	24%	0.242	30%	0.296	C	S	.	.	H	α-helix	trans	-45.7	-40.2	-173.9	-171.3	0	0	0	0	113.8	L182 Y357 H434 L435 T436	L182-V432 HydrophobicContact CD1-CB 4.21Å; L182-V432 HydrophobicContact CD1-CG1 3.87Å; L182-V432 HydrophobicContact CD1-CG2 3.79Å; Y357-V432 HydrophobicContact CD1-CG1 3.83Å; Y357-V432 HydrophobicContact CE1-CG1 4.3Å; Y357-V432 HydrophobicContact CG-CG1 4.39Å; V432-H434 PolarHBondContact O-N 3.35Å; V432-L435 WeakPolarHBondContact O-CB 3.38Å; V432-L435 PolarHBondContact O-N 2.8Å; V432-T436 PolarHBondContact O-N 3.29Å
433	E	59.3	Low	73.5	Confident	111 Å²	111	54.7 Å²	54.7	52%	0.519	29%	0.285	S	S	.	.	H	α-helix	trans	-64.9	-22.9	-176.6	-50.8	-157.1	109.2	0	0	113.5	K358 D431 T436 G437	K358-E433 WeakPolarHBondContact CE-OE1 3.35Å; K358-E433 IonicContact NZ-OE1 3.81Å; K358-E433 PolarHBondContact NZ-OE1 3.17Å; D431-E433 PolarHBondContact O-N 3.05Å; E433-T436 PolarHBondContact O-OG1 3.02Å; E433-G437 PolarHBondContact O-N 2.86Å; E433-G437 VanDerWaalsContact O-N 3.08Å
434	H	62.7	Low	73.3	Confident	98 Å²	98	57.2 Å²	57.2	45%	0.454	30%	0.301	S	S	.	.	H	α-helix	trans	-80.8	-23.6	174.9	-61.8	83.3	0	0	0	112.3	V426 Q430 D431 V432 M438	V426-H434 HydrophobicContact CG1-CB 4.16Å; Q430-H434 HydrophobicContact CB-CB 3.75Å; Q430-H434 HydrophobicContact CG-CB 4.39Å; D431-H434 WeakPolarHBondContact O-CB 3.45Å; D431-H434 PolarHBondContact O-N 2.92Å; V432-H434 PolarHBondContact O-N 3.35Å; H434-M438 WeakPolarHBondContact O-CB 2.97Å; H434-M438 PolarHBondContact O-N 2.86Å
435	L	63.5	Low	73.1	Confident	7 Å²	7	57 Å²	57	4%	0.037	30%	0.299	C	S	.	.	H	α-helix	trans	-75.8	-33.9	171.9	-73	168.2	0	0	0	111.8	L182 T423 V426 A427 V432 M438 N439	L182-L435 HydrophobicContact CB-CD1 4.12Å; L182-L435 HydrophobicContact CD1-CD1 3.67Å; L182-L435 HydrophobicContact CG-CD1 4.48Å; T423-L435 HydrophobicContact CG2-CD2 4.39Å; V426-L435 HydrophobicContact CB-CD2 3.84Å; V426-L435 HydrophobicContact CG1-CD2 3.58Å; V426-L435 HydrophobicContact CG1-CG 3.9Å; A427-L435 HydrophobicContact CB-CD1 3.87Å; A427-L435 HydrophobicContact CB-CD2 4.14Å; V432-L435 WeakPolarHBondContact O-CB 3.38Å; V432-L435 PolarHBondContact O-N 2.8Å; L435-M438 HydrophobicContact CD2-CE 3.85Å; L435-M438 WeakPolarHBondContact O-CB 3.15Å; L435-N439 PolarHBondContact O-N 3.44Å
436	T	62.3	Low	73.1	Confident	8 Å²	8	52.6 Å²	52.6	5%	0.049	28%	0.276	C	S	.	.	H	α-helix	trans	-82.2	-40.7	-179.4	55.5	0	0	0	0	111.6	I170 D355 V432 E433 M438 N439 D440	I170-T436 HydrophobicContact CD1-CG2 4.12Å; D355-T436 VanDerWaalsContact CB-CB 3.45Å; D355-T436 HydrophobicContact CB-CG2 3.54Å; D355-T436 VanDerWaalsContact CG-CG2 3.5Å; D355-T436 PolarHBondContact OD2-OG1 2.93Å; V432-T436 PolarHBondContact O-N 3.29Å; E433-T436 PolarHBondContact O-OG1 3.02Å; T436-M438 PolarHBondContact O-N 3.36Å; T436-N439 WeakPolarHBondContact O-CB 3.46Å; T436-N439 PolarHBondContact O-N 3.07Å; T436-D440 PolarHBondContact O-N 2.89Å
437	G	68.5	Low	73.2	Confident	38 Å²	38	51.4 Å²	51.4	39%	0.392	27%	0.27	S	S	.	.	H	α-helix	trans	-60.3	-23.3	166.6	0	0	0	0	0	114.2	E433 F441	E433-G437 PolarHBondContact O-N 2.86Å; E433-G437 VanDerWaalsContact O-N 3.08Å; G437-F441 PolarHBondContact O-N 3.44Å
438	M	73.8	Confident	73.5	Confident	26 Å²	26	52.7 Å²	52.7	13%	0.128	28%	0.275	C	S	.	.	H	α-helix	trans	-70.4	-33.8	170.6	-178.2	165.5	73.1	0	0	112.3	M162 I166 T423 V426 H434 L435 T436 F441 L442	M162-M438 HydrophobicContact CE-CE 3.89Å; M162-M438 HydrophobicContact CE-CG 4.33Å; M162-M438 HydrophobicContact CE-SD 3.52Å; M162-M438 VanDerWaalsContact CE-SD 3.52Å; I166-M438 HydrophobicContact CD1-CE 3.64Å; I166-M438 HydrophobicContact CD1-CG 4.45Å; I166-M438 HydrophobicContact CG1-CE 4.06Å; T423-M438 HydrophobicContact CG2-CE 4.09Å; V426-M438 HydrophobicContact CB-CE 4.42Å; V426-M438 HydrophobicContact CG2-CE 4.42Å; V426-M438 HydrophobicContact CG2-SD 4.05Å; H434-M438 WeakPolarHBondContact O-CB 2.97Å; H434-M438 PolarHBondContact O-N 2.86Å; L435-M438 HydrophobicContact CD2-CE 3.85Å; L435-M438 WeakPolarHBondContact O-CB 3.15Å; T436-M438 PolarHBondContact O-N 3.36Å; M438-F441 PolarHBondContact O-N 3.13Å; M438-L442 HydrophobicContact CG-CD1 4.09Å; M438-L442 WeakPolarHBondContact O-CD1 3.45Å; M438-L442 WeakPolarHBondContact O-CG 3.18Å; M438-L442 PolarHBondContact O-N 3.47Å
439	N	76.3	Confident	73.9	Confident	1 Å²	1	49.4 Å²	49.4	1%	0.005	25%	0.254	C	S	.	.	H	α-helix	trans	-67.7	-38.9	175.2	-174.4	78.4	0	0	0	112	E91 Q163 L435 T436 F441 L442 N443	E91-N439 WeakPolarHBondContact CB-ND2 3.32Å; E91-N439 WeakPolarHBondContact CG-ND2 3.1Å; E91-N439 WeakPolarHBondContact OE2-CB 3.45Å; E91-N439 PolarHBondContact OE2-ND2 3.23Å; Q163-N439 WeakPolarHBondContact CB-OD1 3.29Å; Q163-N439 WeakPolarHBondContact CG-OD1 3.16Å; Q163-N439 PolarHBondContact NE2-OD1 3.17Å; L435-N439 PolarHBondContact O-N 3.44Å; T436-N439 WeakPolarHBondContact O-CB 3.46Å; T436-N439 PolarHBondContact O-N 3.07Å; N439-F441 VanDerWaalsContact C-N 3.34Å; N439-F441 PolarHBondContact O-N 2.98Å; N439-L442 CarbonylContact O-C 3.5Å; N439-L442 WeakPolarHBondContact O-CA 3.47Å; N439-L442 WeakPolarHBondContact O-CB 3.49Å; N439-L442 PolarHBondContact O-N 3.27Å; N439-L442 VanDerWaalsContact O-N 3.09Å; N439-N443 PolarHBondContact O-N 2.76Å
440	D	74.3	Confident	74.5	Confident	59 Å²	59	42.3 Å²	42.3	32%	0.316	22%	0.223	S	C	.	.	H	α-helix	trans	-60	-45.1	174.9	-65.8	-12.3	0	0	0	111.6	Q95 T436 L442 N443 V444	Q95-D440 PolarHBondContact NE2-OD1 3.45Å; Q95-D440 PolarHBondContact NE2-OD2 3.06Å; T436-D440 PolarHBondContact O-N 2.89Å; D440-L442 VanDerWaalsContact C-N 3.31Å; D440-L442 PolarHBondContact O-N 3.27Å; D440-N443 PolarHBondContact O-N 2.95Å; D440-V444 PolarHBondContact O-N 3.28Å
441	F	78.3	Confident	75.8	Confident	104 Å²	104	37.5 Å²	37.5	46%	0.456	20%	0.201	S	C	.	.	H	α-helix	trans	-61.1	-38.2	173.3	177.7	-96.6	0	0	0	112.4	G437 M438 N439 V444 L445 Y498	G437-F441 PolarHBondContact O-N 3.44Å; M438-F441 PolarHBondContact O-N 3.13Å; N439-F441 VanDerWaalsContact C-N 3.34Å; N439-F441 PolarHBondContact O-N 2.98Å; F441-V444 PolarHBondContact O-N 3.48Å; F441-L445 PolarHBondContact O-N 3.04Å; F441-Y498 HydrophobicContact CE2-CE2 4.45Å
442	L	82.8	Confident	77.2	Confident	6 Å²	6	31.5 Å²	31.5	3%	0.031	17%	0.169	C	C	.	.	H	α-helix	trans	-68.4	-36.7	176.3	-70.1	166.9	0	0	0	112.3	M162 Q163 I166 M438 N439 D440 L445 Q446	M162-L442 HydrophobicContact CB-CD1 3.64Å; M162-L442 HydrophobicContact CE-CD1 4.38Å; M162-L442 HydrophobicContact SD-CD2 4.41Å; Q163-L442 HydrophobicContact CG-CB 3.68Å; Q163-L442 HydrophobicContact CG-CD1 3.67Å; Q163-L442 HydrophobicContact CG-CG 4.28Å; I166-L442 HydrophobicContact CD1-CD1 4.09Å; M438-L442 HydrophobicContact CG-CD1 4.09Å; M438-L442 WeakPolarHBondContact O-CD1 3.45Å; M438-L442 WeakPolarHBondContact O-CG 3.18Å; M438-L442 PolarHBondContact O-N 3.47Å; N439-L442 CarbonylContact O-C 3.5Å; N439-L442 WeakPolarHBondContact O-CA 3.47Å; N439-L442 WeakPolarHBondContact O-CB 3.49Å; N439-L442 PolarHBondContact O-N 3.27Å; N439-L442 VanDerWaalsContact O-N 3.09Å; D440-L442 VanDerWaalsContact C-N 3.31Å; D440-L442 PolarHBondContact O-N 3.27Å; L442-L445 HydrophobicContact CD2-CD2 4.11Å; L442-L445 CarbonylContact O-C 3.44Å; L442-L445 WeakPolarHBondContact O-CA 3.32Å; L442-L445 WeakPolarHBondContact O-CB 3.45Å; L442-L445 PolarHBondContact O-N 3.02Å; L442-Q446 WeakPolarHBondContact O-CG 3.41Å; L442-Q446 PolarHBondContact O-N 2.9Å
443	N	80.8	Confident	78.7	Confident	9 Å²	9	29.6 Å²	29.6	5%	0.048	16%	0.157	C	C	.	.	H	α-helix	trans	-63.6	-40.3	171.4	-83.4	-20.6	0	0	0	112.2	G88 Q163 N439 D440 L445 Q446 S447	G88-N443 PolarHBondContact O-ND2 2.99Å; G88-N443 PolarHBondContact O-OD1 3.36Å; Q163-N443 PolarHBondContact NE2-OD1 2.99Å; N439-N443 PolarHBondContact O-N 2.76Å; D440-N443 PolarHBondContact O-N 2.95Å; N443-L445 VanDerWaalsContact C-N 3.33Å; N443-Q446 PolarHBondContact O-N 3.2Å; N443-S447 PolarHBondContact O-N 3.23Å; N443-S447 VanDerWaalsContact O-N 3.15Å
444	V	78.3	Confident	80.3	Confident	53 Å²	53	24.5 Å²	24.5	32%	0.321	13%	0.134	S	C	.	.	H	α-helix	trans	-63.6	-39.5	171	175.8	0	0	0	0	111.1	D440 F441 S447 L448 F494	D440-V444 PolarHBondContact O-N 3.28Å; F441-V444 PolarHBondContact O-N 3.48Å; V444-S447 WeakPolarHBondContact O-CB 3.39Å; V444-S447 PolarHBondContact O-N 3.33Å; V444-L448 HydrophobicContact CG1-CD1 4.33Å; V444-L448 WeakPolarHBondContact O-CG 3.08Å; V444-L448 PolarHBondContact O-N 3.02Å; V444-F494 HydrophobicContact CG1-CD1 4.17Å; V444-F494 HydrophobicContact CG2-CE1 4.45Å
445	L	83.9	Confident	81.7	Confident	40 Å²	40	19.9 Å²	19.9	21%	0.209	11%	0.112	C	C	.	.	H	α-helix	trans	-60.8	-45.9	174.2	-178.8	65.4	0	0	0	111.7	F441 L442 N443 S447 L448 Q449	F441-L445 PolarHBondContact O-N 3.04Å; L442-L445 HydrophobicContact CD2-CD2 4.11Å; L442-L445 CarbonylContact O-C 3.44Å; L442-L445 WeakPolarHBondContact O-CA 3.32Å; L442-L445 WeakPolarHBondContact O-CB 3.45Å; L442-L445 PolarHBondContact O-N 3.02Å; N443-L445 VanDerWaalsContact C-N 3.33Å; L445-S447 VanDerWaalsContact C-N 3.28Å; L445-S447 PolarHBondContact O-N 3.06Å; L445-L448 PolarHBondContact O-N 3.38Å; L445-L448 VanDerWaalsContact O-N 3.13Å; L445-Q449 HydrophobicContact CD1-CG 4.36Å; L445-Q449 HydrophobicContact CG-CG 4.47Å; L445-Q449 VanDerWaalsContact O-CG 3.29Å; L445-Q449 WeakPolarHBondContact O-CG 3.38Å; L445-Q449 PolarHBondContact O-N 3.38Å
446	Q	85.5	Confident	83.1	Confident	0 Å²	0	19.6 Å²	19.6	0%	0	11%	0.11	C	C	.	.	H	α-helix	trans	-58	-41.9	175.9	-63.1	-56.7	-15.5	0	0	111.7	A156 S160 P266 L442 N443 L448 Q449 L450	A156-Q446 PolarHBondContact O-NE2 2.86Å; A156-Q446 PolarHBondContact O-OE1 3.24Å; S160-Q446 VanDerWaalsContact N-NE2 3.17Å; P266-Q446 WeakPolarHBondContact CG-O 3.31Å; L442-Q446 WeakPolarHBondContact O-CG 3.41Å; L442-Q446 PolarHBondContact O-N 2.9Å; N443-Q446 PolarHBondContact O-N 3.2Å; Q446-L448 PolarHBondContact O-N 2.93Å; Q446-Q449 PolarHBondContact O-N 3.42Å; Q446-Q449 VanDerWaalsContact O-N 3.1Å; Q446-L450 PolarHBondContact O-N 3.18Å
447	S	83.6	Confident	84.5	Confident	10 Å²	10	19.2 Å²	19.2	7%	0.07	11%	0.108	C	C	.	.	H	α-helix	trans	-59.7	-43.8	175.4	-163.2	0	0	0	0	112	N443 V444 L445 Q449 L450 N491	N443-S447 PolarHBondContact O-N 3.23Å; N443-S447 VanDerWaalsContact O-N 3.15Å; V444-S447 WeakPolarHBondContact O-CB 3.39Å; V444-S447 PolarHBondContact O-N 3.33Å; L445-S447 VanDerWaalsContact C-N 3.28Å; L445-S447 PolarHBondContact O-N 3.06Å; S447-Q449 VanDerWaalsContact C-N 3.27Å; S447-Q449 PolarHBondContact O-N 2.84Å; S447-L450 WeakPolarHBondContact O-CB 3.45Å; S447-L450 PolarHBondContact O-N 2.96Å; S447-N491 VanDerWaalsContact O-CG 3.32Å; S447-N491 PolarHBondContact O-ND2 2.99Å; S447-N491 PolarHBondContact O-OD1 3.06Å; S447-N491 VanDerWaalsContact O-OD1 3.09Å
448	L	85.2	Confident	85.7	Confident	39 Å²	39	17.6 Å²	17.6	20%	0.204	9%	0.091	C	C	.	.	H	α-helix	trans	-65.6	-26.5	175.1	-68.8	169.7	0	0	0	113.2	V444 L445 Q446 P451 N491 V495 Y518	V444-L448 HydrophobicContact CG1-CD1 4.33Å; V444-L448 WeakPolarHBondContact O-CG 3.08Å; V444-L448 PolarHBondContact O-N 3.02Å; L445-L448 PolarHBondContact O-N 3.38Å; L445-L448 VanDerWaalsContact O-N 3.13Å; Q446-L448 PolarHBondContact O-N 2.93Å; L448-P451 WeakPolarHBondContact O-CD 3.47Å; L448-N491 WeakPolarHBondContact CA-OD1 3.35Å; L448-N491 HydrophobicContact CD2-CB 4.19Å; L448-N491 PolarHBondContact N-OD1 2.7Å; L448-V495 HydrophobicContact CD2-CG2 3.59Å; L448-Y518 WeakPolarHBondContact O-CE2 3.17Å; L448-Y518 PolarHBondContact O-OH 3.47Å; L448-Y518 VanDerWaalsContact O-OH 3.07Å
449	Q	90.4	Very high	86.5	Confident	10 Å²	10	16.4 Å²	16.4	5%	0.047	9%	0.085	C	C	.	.	H	α-helix	trans	-85	-13.2	179	-62	-61.8	-19.4	0	0	113.5	M152 A156 P266 L445 Q446 S447 P451 F452	M152-Q449 VanDerWaalsContact CB-OE1 3.32Å; M152-Q449 PolarHBondContact O-OE1 3.06Å; M152-Q449 VanDerWaalsContact O-OE1 3.08Å; A156-Q449 HydrophobicContact CB-CB 3.8Å; A156-Q449 HydrophobicContact CB-CG 3.87Å; P266-Q449 HydrophobicContact CB-CB 4.45Å; P266-Q449 HydrophobicContact CG-CB 3.86Å; L445-Q449 HydrophobicContact CD1-CG 4.36Å; L445-Q449 HydrophobicContact CG-CG 4.47Å; L445-Q449 VanDerWaalsContact O-CG 3.29Å; L445-Q449 WeakPolarHBondContact O-CG 3.38Å; L445-Q449 PolarHBondContact O-N 3.38Å; Q446-Q449 PolarHBondContact O-N 3.42Å; Q446-Q449 VanDerWaalsContact O-N 3.1Å; S447-Q449 VanDerWaalsContact C-N 3.27Å; S447-Q449 PolarHBondContact O-N 2.84Å; Q449-P451 VanDerWaalsContact C-CD 3.48Å; Q449-F452 WeakPolarHBondContact O-CB 3.5Å; Q449-F452 PolarHBondContact O-N 3.29Å; Q449-F452 VanDerWaalsContact O-N 3.16Å
450	L	88.4	Confident	87.2	Confident	1 Å²	1	16.3 Å²	16.3	1%	0.005	8%	0.084	C	C	.	.	H	α-helix	trans	-49.4	-48	179.3	-95.7	169.7	0	0	0	115.9	I264 P266 Q446 S447 F452 A453 L454 I487	I264-L450 HydrophobicContact CB-CD2 3.94Å; I264-L450 HydrophobicContact CG2-CD2 3.57Å; I264-L450 WeakPolarHBondContact O-CD2 3.46Å; P266-L450 HydrophobicContact CG-CG 4.41Å; Q446-L450 PolarHBondContact O-N 3.18Å; S447-L450 WeakPolarHBondContact O-CB 3.45Å; S447-L450 PolarHBondContact O-N 2.96Å; L450-F452 PolarHBondContact O-N 3.24Å; L450-F452 VanDerWaalsContact O-N 3.09Å; L450-A453 PolarHBondContact O-N 2.95Å; L450-L454 VanDerWaalsContact O-CB 3.25Å; L450-L454 WeakPolarHBondContact O-CB 3.33Å; L450-L454 PolarHBondContact O-N 3.13Å; L450-I487 HydrophobicContact CB-CG2 3.81Å; L450-I487 HydrophobicContact CD1-CD1 4.49Å; L450-I487 HydrophobicContact CD1-CG2 4.02Å
451	P	91.4	Very high	88	Confident	1 Å²	1	13.5 Å²	13.5	1%	0.006	7%	0.069	C	C	.	.	H	α-helix	trans	-57.4	-29.2	-177.1	-25.5	35.8	0	0	0	112.9	L448 Q449 I455 I487 V522	L448-P451 WeakPolarHBondContact O-CD 3.47Å; Q449-P451 VanDerWaalsContact C-CD 3.48Å; P451-I455 HydrophobicContact CB-CD1 3.84Å; P451-I455 HydrophobicContact CB-CG1 4.43Å; P451-I455 VanDerWaalsContact O-CB 3.23Å; P451-I455 WeakPolarHBondContact O-CB 3.11Å; P451-I455 WeakPolarHBondContact O-CG1 3.4Å; P451-I455 PolarHBondContact O-N 3.39Å; P451-I487 HydrophobicContact CG-CG2 4.49Å; P451-V522 HydrophobicContact CB-CG1 4.04Å; P451-V522 HydrophobicContact CB-CG2 4.18Å; P451-V522 HydrophobicContact CG-CG1 4.49Å
452	F	92.5	Very high	88.4	Confident	1 Å²	1	8.6 Å²	8.6	0%	0.004	5%	0.048	C	C	.	.	H	α-helix	trans	-74.1	-29.7	-176.8	-60.2	-50	0	0	0	113.9	L149 M152 Y270 Q449 L450 P456 Y518 F521 V522 L525	L149-F452 HydrophobicContact CD1-CB 3.61Å; L149-F452 HydrophobicContact CD1-CD1 4.06Å; L149-F452 HydrophobicContact CD1-CG 4.15Å; M152-F452 HydrophobicContact CB-CB 4.49Å; M152-F452 HydrophobicContact CB-CD2 3.61Å; M152-F452 HydrophobicContact CB-CE2 3.93Å; M152-F452 HydrophobicContact CB-CG 4Å; M152-F452 HydrophobicContact CE-CE2 4.22Å; M152-F452 HydrophobicContact CE-CZ 4.16Å; M152-F452 HydrophobicContact CG-CD2 3.85Å; M152-F452 HydrophobicContact CG-CE1 4.47Å; M152-F452 HydrophobicContact CG-CE2 3.62Å; M152-F452 HydrophobicContact CG-CG 4.34Å; M152-F452 HydrophobicContact CG-CZ 3.98Å; M152-F452 HydrophobicContact SD-CD2 4.34Å; M152-F452 HydrophobicContact SD-CE2 3.7Å; M152-F452 HydrophobicContact SD-CZ 4.22Å; Y270-F452 PolarHBondContact OH-O 3.26Å; Q449-F452 WeakPolarHBondContact O-CB 3.5Å; Q449-F452 PolarHBondContact O-N 3.29Å; Q449-F452 VanDerWaalsContact O-N 3.16Å; L450-F452 PolarHBondContact O-N 3.24Å; L450-F452 VanDerWaalsContact O-N 3.09Å; F452-P456 WeakPolarHBondContact O-CD 3.45Å; F452-P456 WeakPolarHBondContact O-CG 3.34Å; F452-Y518 AromaticContact CE2-CD2 3.9Å; F452-Y518 HydrophobicContact CE2-CD2 3.9Å; F452-Y518 AromaticContact CE2-CE2 3.58Å; F452-Y518 HydrophobicContact CE2-CE2 3.58Å; F452-Y518 AromaticContact CZ-CD2 3.63Å; F452-Y518 HydrophobicContact CZ-CD2 3.63Å; F452-Y518 AromaticContact CZ-CE2 3.55Å; F452-Y518 HydrophobicContact CZ-CE2 3.55Å; F452-F521 HydrophobicContact CD1-CD1 4.13Å; F452-F521 AromaticContact CD1-CE1 3.95Å; F452-F521 HydrophobicContact CD1-CE1 3.95Å; F452-F521 AromaticContact CE1-CD1 3.37Å; F452-F521 HydrophobicContact CE1-CD1 3.37Å; F452-F521 AromaticContact CE1-CE1 3.68Å; F452-F521 HydrophobicContact CE1-CE1 3.68Å; F452-F521 HydrophobicContact CE1-CG 4.43Å; F452-F521 AromaticContact CZ-CD1 3.99Å; F452-F521 HydrophobicContact CZ-CD1 3.99Å; F452-V522 HydrophobicContact CE1-CG2 3.67Å; F452-V522 HydrophobicContact CZ-CG2 3.69Å; F452-L525 HydrophobicContact CD1-CD1 3.68Å; F452-L525 HydrophobicContact CE1-CD1 4.1Å
453	A	91.9	Very high	88.6	Confident	0 Å²	0	9.8 Å²	9.8	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-82.3	-44	168.2	0	0	0	0	0	111.7	P266 M269 Y270 L450 I457	P266-A453 HydrophobicContact CB-CB 3.75Å; P266-A453 VanDerWaalsContact O-CB 3.26Å; P266-A453 WeakPolarHBondContact O-CB 3.46Å; M269-A453 HydrophobicContact CB-CB 4.15Å; M269-A453 HydrophobicContact CG-CB 4.04Å; M269-A453 HydrophobicContact SD-CB 3.96Å; Y270-A453 HydrophobicContact CD2-CB 4.49Å; Y270-A453 HydrophobicContact CE2-CB 3.78Å; L450-A453 PolarHBondContact O-N 2.95Å; A453-I457 WeakPolarHBondContact O-CB 3.42Å; A453-I457 WeakPolarHBondContact O-CG2 3.25Å; A453-I457 PolarHBondContact O-N 3.25Å
454	L	91.7	Very high	88.8	Confident	4 Å²	4	18.7 Å²	18.7	2%	0.021	9%	0.087	C	C	.	.	H	α-helix	trans	-78.9	-32.3	-164.9	-171.9	144.4	0	0	0	113.5	L118 L450 I457 L458 L483 V484 I487	L118-L454 HydrophobicContact CD1-CD1 3.63Å; L118-L454 HydrophobicContact CD2-CD1 3.69Å; L118-L454 HydrophobicContact CD2-CG 3.98Å; L118-L454 HydrophobicContact CG-CD1 4.33Å; L450-L454 VanDerWaalsContact O-CB 3.25Å; L450-L454 WeakPolarHBondContact O-CB 3.33Å; L450-L454 PolarHBondContact O-N 3.13Å; L454-I457 WeakPolarHBondContact O-CG2 3.43Å; L454-L458 PolarHBondContact O-N 2.93Å; L454-L483 HydrophobicContact CD1-CD2 4.36Å; L454-L483 HydrophobicContact CD1-CG 4.45Å; L454-V484 HydrophobicContact CD2-CB 4.08Å; L454-V484 HydrophobicContact CD2-CG2 3.4Å; L454-V484 VanDerWaalsContact CD2-CG2 3.4Å; L454-I487 HydrophobicContact CD1-CD1 3.57Å
455	I	92.4	Very high	89.1	Confident	1 Å²	1	20.8 Å²	20.8	1%	0.005	10%	0.102	C	C	.	.	H	α-helix	trans	-73.1	-50.3	176.9	-62	170.5	0	0	0	111.7	P451 I457 L458 T459 V484 V522 L525 C529	P451-I455 HydrophobicContact CB-CD1 3.84Å; P451-I455 HydrophobicContact CB-CG1 4.43Å; P451-I455 VanDerWaalsContact O-CB 3.23Å; P451-I455 WeakPolarHBondContact O-CB 3.11Å; P451-I455 WeakPolarHBondContact O-CG1 3.4Å; P451-I455 PolarHBondContact O-N 3.39Å; I455-I457 VanDerWaalsContact C-N 3.33Å; I455-I457 PolarHBondContact O-N 3.34Å; I455-L458 PolarHBondContact O-N 2.92Å; I455-T459 WeakPolarHBondContact O-CB 3.41Å; I455-T459 PolarHBondContact O-N 3.35Å; I455-T459 PolarHBondContact O-OG1 2.91Å; I455-V484 HydrophobicContact CD1-CG1 4.18Å; I455-V484 HydrophobicContact CG1-CG1 3.78Å; I455-V484 HydrophobicContact CG1-CG2 4.43Å; I455-V522 HydrophobicContact CD1-CG1 4.18Å; I455-L525 HydrophobicContact CB-CB 4.47Å; I455-L525 HydrophobicContact CD1-CB 4.39Å; I455-L525 HydrophobicContact CG2-CB 3.92Å; I455-L525 WeakPolarHBondContact CG2-O 3.48Å; I455-C529 HydrophobicContact CG2-CB 3.63Å
456	P	92.9	Very high	89.1	Confident	0 Å²	0	19.6 Å²	19.6	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-60.5	-39	177.2	-27.4	38.6	0	0	0	113.2	L133 Y141 L149 F452 T459 F460	L133-P456 HydrophobicContact CD1-CB 4.3Å; Y141-P456 HydrophobicContact CE2-CB 4.06Å; Y141-P456 HydrophobicContact CE2-CG 4.09Å; L149-P456 HydrophobicContact CD2-CG 3.97Å; F452-P456 WeakPolarHBondContact O-CD 3.45Å; F452-P456 WeakPolarHBondContact O-CG 3.34Å; P456-T459 WeakPolarHBondContact O-CB 3.41Å; P456-T459 PolarHBondContact O-N 3.21Å; P456-F460 HydrophobicContact CB-CD2 4.2Å; P456-F460 HydrophobicContact CB-CE2 3.86Å; P456-F460 WeakPolarHBondContact O-CD2 3.33Å; P456-F460 WeakPolarHBondContact O-CG 3.4Å; P456-F460 PolarHBondContact O-N 3.44Å
457	I	92.8	Very high	89.2	Confident	0 Å²	0	19.6 Å²	19.6	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-70.3	-37.3	-177.5	-154.5	165.4	0	0	0	112.5	L121 A122 L125 L133 M269 A453 L454 I455 T461	L121-I457 HydrophobicContact CB-CG1 4.5Å; A122-I457 VanDerWaalsContact CA-CD1 3.4Å; A122-I457 HydrophobicContact CB-CD1 3.54Å; L125-I457 HydrophobicContact CD2-CG1 4.42Å; L133-I457 HydrophobicContact CD1-CB 4.03Å; L133-I457 HydrophobicContact CD1-CG1 4.12Å; L133-I457 HydrophobicContact CD2-CB 3.99Å; L133-I457 HydrophobicContact CD2-CD1 3.97Å; L133-I457 HydrophobicContact CD2-CG1 4.21Å; M269-I457 HydrophobicContact CB-CD1 4.35Å; M269-I457 HydrophobicContact CE-CD1 3.62Å; M269-I457 HydrophobicContact CE-CG2 3.86Å; M269-I457 HydrophobicContact SD-CG2 4.21Å; A453-I457 WeakPolarHBondContact O-CB 3.42Å; A453-I457 WeakPolarHBondContact O-CG2 3.25Å; A453-I457 PolarHBondContact O-N 3.25Å; L454-I457 WeakPolarHBondContact O-CG2 3.43Å; I455-I457 VanDerWaalsContact C-N 3.33Å; I455-I457 PolarHBondContact O-N 3.34Å; I457-T461 HydrophobicContact CG1-CG2 4.43Å; I457-T461 WeakPolarHBondContact O-CB 3.24Å; I457-T461 WeakPolarHBondContact O-CG2 3.34Å; I457-T461 PolarHBondContact O-N 2.88Å; I457-T461 PolarHBondContact O-OG1 3.4Å
458	L	91.9	Very high	89.2	Confident	5 Å²	5	22.7 Å²	22.7	3%	0.026	12%	0.118	C	C	.	.	H	α-helix	trans	-67	-39.8	171.5	-177	64.4	0	0	0	111.4	L454 I455 S462 V484 L533	L454-L458 PolarHBondContact O-N 2.93Å; I455-L458 PolarHBondContact O-N 2.92Å; L458-S462 WeakPolarHBondContact O-CB 3.13Å; L458-S462 PolarHBondContact O-N 3.42Å; L458-S462 VanDerWaalsContact O-N 3.11Å; L458-S462 PolarHBondContact O-OG 3.24Å; L458-V484 HydrophobicContact CD2-CG2 3.63Å; L458-L533 HydrophobicContact CD2-CD1 4.26Å; L458-L533 HydrophobicContact CD2-CD2 4.33Å; L458-L533 HydrophobicContact CG-CD2 4.3Å
459	T	90.3	Very high	89.2	Confident	0 Å²	0	26.2 Å²	26.2	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-56.6	-60.3	175.5	-57.9	0	0	0	0	110.4	I455 P456 S462 L463 C529 A532	I455-T459 WeakPolarHBondContact O-CB 3.41Å; I455-T459 PolarHBondContact O-N 3.35Å; I455-T459 PolarHBondContact O-OG1 2.91Å; P456-T459 WeakPolarHBondContact O-CB 3.41Å; P456-T459 PolarHBondContact O-N 3.21Å; T459-S462 PolarHBondContact O-N 2.57Å; T459-L463 HydrophobicContact CG2-CD1 4.13Å; T459-L463 WeakPolarHBondContact O-CG 3.45Å; T459-L463 PolarHBondContact O-N 2.83Å; T459-L463 VanDerWaalsContact O-N 3.11Å; T459-C529 WeakPolarHBondContact OG1-CA 3.4Å; T459-C529 VanDerWaalsContact OG1-CB 3.25Å; T459-C529 WeakPolarHBondContact OG1-CB 3.35Å; T459-C529 PolarHBondContact OG1-SG 2.77Å; T459-A532 HydrophobicContact CG2-CB 3.74Å
460	F	91.3	Very high	89	Confident	0 Å²	0	28 Å²	28	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-70.7	-36.1	-173.9	-60.2	-47.8	0	0	0	113.3	L125 L133 V136 Q140 Y141 P456 S462 L463 V466 M467	L125-F460 HydrophobicContact CD1-CB 4.01Å; L125-F460 HydrophobicContact CD2-CB 4.49Å; L133-F460 HydrophobicContact CD1-CD2 3.97Å; V136-F460 HydrophobicContact CB-CD2 4.31Å; V136-F460 HydrophobicContact CG1-CB 4.02Å; V136-F460 HydrophobicContact CG1-CD1 3.8Å; V136-F460 HydrophobicContact CG1-CD2 3.65Å; V136-F460 HydrophobicContact CG1-CE1 4.23Å; V136-F460 HydrophobicContact CG1-CE2 4.05Å; V136-F460 HydrophobicContact CG1-CG 3.53Å; V136-F460 HydrophobicContact CG1-CZ 4.34Å; Q140-F460 HydrophobicContact CB-CD1 4.44Å; Q140-F460 HydrophobicContact CB-CE1 3.41Å; Q140-F460 VanDerWaalsContact CB-CE1 3.41Å; Q140-F460 HydrophobicContact CB-CZ 3.65Å; Q140-F460 HydrophobicContact CG-CD1 4.2Å; Q140-F460 HydrophobicContact CG-CE1 3.63Å; Q140-F460 HydrophobicContact CG-CZ 4.2Å; Y141-F460 HydrophobicContact CD2-CZ 4.15Å; Y141-F460 HydrophobicContact CE1-CZ 4.46Å; Y141-F460 AromaticContact CE2-CE2 3.87Å; Y141-F460 HydrophobicContact CE2-CE2 3.87Å; Y141-F460 AromaticContact CE2-CZ 3.64Å; Y141-F460 HydrophobicContact CE2-CZ 3.64Å; Y141-F460 AromaticContact CZ-CZ 3.81Å; P456-F460 HydrophobicContact CB-CD2 4.2Å; P456-F460 HydrophobicContact CB-CE2 3.86Å; P456-F460 WeakPolarHBondContact O-CD2 3.33Å; P456-F460 WeakPolarHBondContact O-CG 3.4Å; P456-F460 PolarHBondContact O-N 3.44Å; F460-S462 PolarHBondContact O-N 3.09Å; F460-L463 HydrophobicContact CD1-CD1 4.06Å; F460-L463 PolarHBondContact O-N 3.31Å; F460-V466 HydrophobicContact CB-CG1 4.37Å; F460-V466 HydrophobicContact CD1-CG2 4.49Å; F460-M467 WeakPolarHBondContact O-CG 3.13Å
461	T	90.8	Very high	89	Confident	0 Å²	0	29.2 Å²	29.2	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-71.9	-14.8	174.5	59.3	0	0	0	0	113.5	L121 L125 I457 M467 N472	L121-T461 HydrophobicContact CB-CG2 4.19Å; L125-T461 HydrophobicContact CB-CG2 3.93Å; L125-T461 HydrophobicContact CD1-CG2 4.16Å; I457-T461 HydrophobicContact CG1-CG2 4.43Å; I457-T461 WeakPolarHBondContact O-CB 3.24Å; I457-T461 WeakPolarHBondContact O-CG2 3.34Å; I457-T461 PolarHBondContact O-N 2.88Å; I457-T461 PolarHBondContact O-OG1 3.4Å; T461-M467 HydrophobicContact CG2-CE 4.1Å; T461-M467 HydrophobicContact CG2-SD 4.28Å; T461-N472 WeakPolarHBondContact CB-ND2 3.39Å; T461-N472 PolarHBondContact O-N 3.36Å; T461-N472 PolarHBondContact O-ND2 2.98Å; T461-N472 PolarHBondContact O-OD1 2.98Å; T461-N472 PolarHBondContact OG1-ND2 3.03Å
462	S	88.4	Confident	88.8	Confident	0 Å²	0	29.6 Å²	29.6	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-89.1	-27.8	172.1	-59.7	0	0	0	0	113.4	L458 T459 F460 R464 R477	L458-S462 WeakPolarHBondContact O-CB 3.13Å; L458-S462 PolarHBondContact O-N 3.42Å; L458-S462 VanDerWaalsContact O-N 3.11Å; L458-S462 PolarHBondContact O-OG 3.24Å; T459-S462 PolarHBondContact O-N 2.57Å; F460-S462 PolarHBondContact O-N 3.09Å; S462-R464 PolarHBondContact O-N 2.74Å; S462-R477 PolarHBondContact O-NH2 3.03Å
463	L	86.3	Confident	88.6	Confident	31 Å²	31	31.6 Å²	31.6	16%	0.162	18%	0.177	C	C	.	.			trans	-71.8	118.1	-176.7	-77.8	170.7	0	0	0	112.8	T459 F460 V466 M467 A532	T459-L463 HydrophobicContact CG2-CD1 4.13Å; T459-L463 WeakPolarHBondContact O-CG 3.45Å; T459-L463 PolarHBondContact O-N 2.83Å; T459-L463 VanDerWaalsContact O-N 3.11Å; F460-L463 HydrophobicContact CD1-CD1 4.06Å; F460-L463 PolarHBondContact O-N 3.31Å; L463-V466 HydrophobicContact CB-CB 4.27Å; L463-V466 HydrophobicContact CB-CG2 4.04Å; L463-V466 HydrophobicContact CD1-CG2 4.44Å; L463-V466 PolarHBondContact O-N 3.08Å; L463-V466 VanDerWaalsContact O-N 3.12Å; L463-M467 PolarHBondContact O-N 2.99Å; L463-A532 HydrophobicContact CD1-CB 4.36Å; L463-A532 HydrophobicContact CD2-CB 3.79Å; L463-A532 HydrophobicContact CG-CB 3.89Å
464	R	84.4	Confident	88.3	Confident	196 Å²	196	37.6 Å²	37.6	74%	0.74	21%	0.209	S	C	*	.	H	α-helix	trans	-57.2	-39.8	173.5	-72.9	-174.2	-179.9	-178.9	0.8	114	S462 V466 S468 A471	S462-R464 PolarHBondContact O-N 2.74Å; R464-V466 PolarHBondContact O-N 2.96Å; R464-S468 VanDerWaalsContact O-CA 3.27Å; R464-S468 WeakPolarHBondContact O-CA 3.27Å; R464-S468 PolarHBondContact O-N 3.32Å; R464-A471 HydrophobicContact CG-CB 3.93Å
465	P	84.4	Confident	88	Confident	98 Å²	98	40 Å²	40	64%	0.636	24%	0.235	S	C	*	.	H	α-helix	trans	-61.9	-23.6	175.9	-26	36.1	0	0	0	114.4
466	V	85.1	Confident	87.7	Confident	15 Å²	15	44.4 Å²	44.4	9%	0.091	25%	0.251	C	S	.	.	H	α-helix	trans	-92.7	-46.2	-179.9	179.8	0	0	0	0	111.2	L125 T129 V136 F460 L463 R464	L125-V466 HydrophobicContact CD1-CG1 4.05Å; T129-V466 HydrophobicContact CG2-CG1 3.59Å; V136-V466 HydrophobicContact CG1-CG1 4.3Å; F460-V466 HydrophobicContact CB-CG1 4.37Å; F460-V466 HydrophobicContact CD1-CG2 4.49Å; L463-V466 HydrophobicContact CB-CB 4.27Å; L463-V466 HydrophobicContact CB-CG2 4.04Å; L463-V466 HydrophobicContact CD1-CG2 4.44Å; L463-V466 PolarHBondContact O-N 3.08Å; L463-V466 VanDerWaalsContact O-N 3.12Å; R464-V466 PolarHBondContact O-N 2.96Å
467	M	86.3	Confident	87.4	Confident	0 Å²	0	46.8 Å²	46.8	0%	0	26%	0.26	C	S	.	.	H	α-helix	trans	-97.1	-6.7	-173.1	-63.9	-70.3	-77.7	0	0	114.7	R124 L125 V128 T129 F460 T461 L463 D469 F470 A471	R124-M467 HydrophobicContact CB-CE 4.21Å; L125-M467 HydrophobicContact CD1-SD 3.79Å; V128-M467 HydrophobicContact CB-CE 4.4Å; V128-M467 HydrophobicContact CB-SD 4.31Å; V128-M467 HydrophobicContact CG1-SD 4.33Å; V128-M467 HydrophobicContact CG2-CE 4.29Å; T129-M467 HydrophobicContact CG2-SD 4.4Å; F460-M467 WeakPolarHBondContact O-CG 3.13Å; T461-M467 HydrophobicContact CG2-CE 4.1Å; T461-M467 HydrophobicContact CG2-SD 4.28Å; L463-M467 PolarHBondContact O-N 2.99Å; M467-D469 PolarHBondContact O-N 3.23Å; M467-F470 WeakPolarHBondContact O-CA 3.39Å; M467-F470 WeakPolarHBondContact O-CB 3.38Å; M467-F470 PolarHBondContact O-N 2.98Å; M467-A471 HydrophobicContact CB-CB 4.07Å
468	S	84.1	Confident	87.2	Confident	75 Å²	75	51.4 Å²	51.4	52%	0.524	28%	0.284	S	S	.	.	G	3₁₀ helix	trans	50.6	-135.7	-173.2	-170.2	0	0	0	0	111.2	R464 F470 A471	R464-S468 VanDerWaalsContact O-CA 3.27Å; R464-S468 WeakPolarHBondContact O-CA 3.27Å; R464-S468 PolarHBondContact O-N 3.32Å; S468-F470 PolarHBondContact O-N 3.44Å; S468-A471 PolarHBondContact O-N 3.12Å
469	D	84.7	Confident	87	Confident	113 Å²	113	53.9 Å²	53.9	60%	0.604	31%	0.305	S	S	*	.	G	3₁₀ helix	trans	-58.3	-16.1	176.1	-62.8	-34	0	0	0	114.3	K286 M467	K286-D469 WeakPolarHBondContact CE-OD2 3.46Å; K286-D469 IonicContact NZ-OD2 3.23Å; K286-D469 PolarHBondContact NZ-OD2 3.21Å; M467-D469 PolarHBondContact O-N 3.23Å
470	F	87.8	Confident	86.8	Confident	48 Å²	48	54.5 Å²	54.5	21%	0.211	31%	0.311	C	S	.	.	G	3₁₀ helix	trans	-93.1	12.1	-179.5	-59.5	-82.7	0	0	0	113.7	R124 V128 K286 V289 R290 M467 S468	R124-F470 PolarHBondContact NH2-O 3.31Å; V128-F470 HydrophobicContact CG1-CB 4.18Å; V128-F470 HydrophobicContact CG1-CD2 4.01Å; V128-F470 HydrophobicContact CG1-CG 4.44Å; V128-F470 HydrophobicContact CG2-CB 3.8Å; V128-F470 HydrophobicContact CG2-CD2 4.03Å; V128-F470 HydrophobicContact CG2-CG 3.9Å; K286-F470 HydrophobicContact CB-CZ 4.41Å; V289-F470 HydrophobicContact CB-CE2 4.17Å; V289-F470 HydrophobicContact CB-CZ 3.95Å; V289-F470 HydrophobicContact CG1-CD2 4.13Å; V289-F470 HydrophobicContact CG1-CE1 4.13Å; V289-F470 HydrophobicContact CG1-CE2 3.58Å; V289-F470 HydrophobicContact CG1-CZ 3.58Å; R290-F470 HydrophobicContact CB-CE1 4.36Å; M467-F470 WeakPolarHBondContact O-CA 3.39Å; M467-F470 WeakPolarHBondContact O-CB 3.38Å; M467-F470 PolarHBondContact O-N 2.98Å; S468-F470 PolarHBondContact O-N 3.44Å
471	A	88.1	Confident	86.6	Confident	26 Å²	26	55.5 Å²	55.5	22%	0.215	32%	0.322	C	S	.	.	P	Polyproline II helix	trans	-58.7	149.9	176.1	0	0	0	0	0	113.4	R464 M467 S468 G473	R464-A471 HydrophobicContact CG-CB 3.93Å; M467-A471 HydrophobicContact CB-CB 4.07Å; S468-A471 PolarHBondContact O-N 3.12Å; A471-G473 PolarHBondContact O-N 3.41Å
472	N	87.7	Confident	86.5	Confident	9 Å²	9	60 Å²	60	5%	0.048	35%	0.345	C	S	.	.	P	Polyproline II helix	trans	-63.2	128.5	179.3	-69.7	-17.3	0	0	0	112.6	R124 T461 W476 R477	R124-N472 PolarHBondContact NH1-OD1 3.18Å; T461-N472 WeakPolarHBondContact CB-ND2 3.39Å; T461-N472 PolarHBondContact O-N 3.36Å; T461-N472 PolarHBondContact O-ND2 2.98Å; T461-N472 PolarHBondContact O-OD1 2.98Å; T461-N472 PolarHBondContact OG1-ND2 3.03Å; N472-W476 HydrophobicContact CB-CB 4.07Å; N472-R477 HydrophobicContact CB-CG 4.3Å; N472-R477 PolarHBondContact O-NE 2.81Å
473	G	86.6	Confident	86.5	Confident	43 Å²	43	61.8 Å²	61.8	44%	0.443	35%	0.354	S	S	.	.	P	Polyproline II helix	trans	-68.8	165.1	171.9	0	0	0	0	0	113.3	A471 G475 W476 R477	A471-G473 PolarHBondContact O-N 3.41Å; G473-G475 PolarHBondContact O-N 3.4Å; G473-W476 WeakPolarHBondContact O-CB 3.39Å; G473-W476 PolarHBondContact O-N 2.68Å; G473-R477 PolarHBondContact O-N 3.47Å
474	L	85.9	Confident	86.5	Confident	125 Å²	125	61.1 Å²	61.1	65%	0.654	35%	0.351	S	S	*	.	H	α-helix	trans	-56.4	-41.7	-169.1	-175.3	60.9	0	0	0	114.2	W476 R477 I478	L474-W476 VanDerWaalsContact C-N 3.32Å; L474-W476 PolarHBondContact O-N 2.89Å; L474-R477 WeakPolarHBondContact O-CB 3.44Å; L474-R477 PolarHBondContact O-N 2.91Å; L474-I478 HydrophobicContact CD1-CD1 3.99Å; L474-I478 HydrophobicContact CD1-CG1 4.23Å; L474-I478 HydrophobicContact CG-CD1 3.86Å; L474-I478 HydrophobicContact CG-CG1 4.48Å; L474-I478 WeakPolarHBondContact O-CG1 3.06Å; L474-I478 PolarHBondContact O-N 2.79Å
475	G	86.6	Confident	86.7	Confident	55 Å²	55	57 Å²	57	57%	0.567	34%	0.344	S	S	*	.	H	α-helix	trans	-61.4	-38.4	176.8	0	0	0	0	0	113.3	G473 A479	G473-G475 PolarHBondContact O-N 3.4Å; G475-A479 VanDerWaalsContact O-CB 3.28Å; G475-A479 WeakPolarHBondContact O-CB 3.45Å; G475-A479 PolarHBondContact O-N 3.21Å
476	W	86.3	Confident	86.8	Confident	94 Å²	94	56.4 Å²	56.4	36%	0.356	33%	0.334	S	S	.	.	H	α-helix	trans	-69.6	-38.5	175.3	-81.2	102.9	0	0	0	112.5	L117 N472 G473 L474 G480	L117-W476 HydrophobicContact CB-CH2 4.01Å; L117-W476 HydrophobicContact CB-CZ3 3.95Å; L117-W476 HydrophobicContact CD1-CH2 3.82Å; L117-W476 HydrophobicContact CD1-CZ3 3.99Å; L117-W476 HydrophobicContact CD2-CH2 4.09Å; L117-W476 HydrophobicContact CG-CH2 4.15Å; L117-W476 HydrophobicContact CG-CZ3 4.44Å; N472-W476 HydrophobicContact CB-CB 4.07Å; G473-W476 WeakPolarHBondContact O-CB 3.39Å; G473-W476 PolarHBondContact O-N 2.68Å; L474-W476 VanDerWaalsContact C-N 3.32Å; L474-W476 PolarHBondContact O-N 2.89Å; W476-G480 PolarHBondContact O-N 3.03Å
477	R	85.8	Confident	86.8	Confident	49 Å²	49	55.9 Å²	55.9	19%	0.185	33%	0.331	C	S	.	.	H	α-helix	trans	-60	-47.8	173	-72.7	178.9	164.4	-133.5	-8.6	111.6	S462 N472 G473 L474 G481 A532 L533	S462-R477 PolarHBondContact O-NH2 3.03Å; N472-R477 HydrophobicContact CB-CG 4.3Å; N472-R477 PolarHBondContact O-NE 2.81Å; G473-R477 PolarHBondContact O-N 3.47Å; L474-R477 WeakPolarHBondContact O-CB 3.44Å; L474-R477 PolarHBondContact O-N 2.91Å; R477-G481 PolarHBondContact O-N 3.44Å; R477-A532 PolarHBondContact NH1-O 3.22Å; R477-A532 PolarHBondContact NH2-O 3.47Å; R477-L533 HydrophobicContact CB-CD2 3.62Å; R477-L533 HydrophobicContact CG-CD2 3.83Å; R477-L533 PolarHBondContact NH1-O 3.03Å
478	I	87.7	Confident	86.6	Confident	98 Å²	98	57.3 Å²	57.3	50%	0.503	34%	0.34	S	S	.	.	H	α-helix	trans	-68.2	-50.1	-179.5	-66.3	168.7	0	0	0	111.1	L474 G480 G481 I482	L474-I478 HydrophobicContact CD1-CD1 3.99Å; L474-I478 HydrophobicContact CD1-CG1 4.23Å; L474-I478 HydrophobicContact CG-CD1 3.86Å; L474-I478 HydrophobicContact CG-CG1 4.48Å; L474-I478 WeakPolarHBondContact O-CG1 3.06Å; L474-I478 PolarHBondContact O-N 2.79Å; I478-G480 VanDerWaalsContact C-N 3.34Å; I478-G480 PolarHBondContact O-N 2.89Å; I478-G481 PolarHBondContact O-N 3.1Å; I478-I482 HydrophobicContact CG2-CD1 3.83Å; I478-I482 WeakPolarHBondContact O-CG1 3.03Å; I478-I482 PolarHBondContact O-N 3.47Å
479	A	88.1	Confident	86.7	Confident	56 Å²	56	57 Å²	57	46%	0.463	34%	0.338	S	S	.	.	H	α-helix	trans	-61.2	-41.7	179.6	0	0	0	0	0	112.2	G475 I482 L483	G475-A479 VanDerWaalsContact O-CB 3.28Å; G475-A479 WeakPolarHBondContact O-CB 3.45Å; G475-A479 PolarHBondContact O-N 3.21Å; A479-I482 PolarHBondContact O-N 2.89Å; A479-L483 WeakPolarHBondContact O-CB 3.45Å; A479-L483 PolarHBondContact O-N 3.03Å
480	G	86.5	Confident	86.5	Confident	13 Å²	13	53.9 Å²	53.9	13%	0.134	32%	0.321	C	S	.	.	H	α-helix	trans	-62.4	-44.1	172.9	0	0	0	0	0	112.6	W476 I478 I482 L483 V484	W476-G480 PolarHBondContact O-N 3.03Å; I478-G480 VanDerWaalsContact C-N 3.34Å; I478-G480 PolarHBondContact O-N 2.89Å; G480-I482 PolarHBondContact O-N 3.17Å; G480-L483 WeakPolarHBondContact O-CB 3.26Å; G480-L483 PolarHBondContact O-N 3.35Å; G480-V484 VanDerWaalsContact O-CG2 3.3Å; G480-V484 WeakPolarHBondContact O-CG2 3.42Å; G480-V484 PolarHBondContact O-N 3.49Å
481	G	87.7	Confident	86.2	Confident	21 Å²	21	51.7 Å²	51.7	22%	0.216	31%	0.311	C	S	.	.	H	α-helix	trans	-63.5	-38.5	178	0	0	0	0	0	113.4	R477 I478 L485	R477-G481 PolarHBondContact O-N 3.44Å; I478-G481 PolarHBondContact O-N 3.1Å; G481-L485 WeakPolarHBondContact O-CB 3.48Å; G481-L485 PolarHBondContact O-N 2.99Å
482	I	89.1	Confident	85.8	Confident	94 Å²	94	54.6 Å²	54.6	48%	0.482	32%	0.321	S	S	.	.	H	α-helix	trans	-64.2	-42.8	173.1	-68.4	166.9	0	0	0	110.5	I478 A479 G480 L485 I486	I478-I482 HydrophobicContact CG2-CD1 3.83Å; I478-I482 WeakPolarHBondContact O-CG1 3.03Å; I478-I482 PolarHBondContact O-N 3.47Å; A479-I482 PolarHBondContact O-N 2.89Å; G480-I482 PolarHBondContact O-N 3.17Å; I482-L485 PolarHBondContact O-N 3.45Å; I482-I486 HydrophobicContact CG2-CD1 3.78Å; I482-I486 HydrophobicContact CG2-CG1 4.45Å; I482-I486 WeakPolarHBondContact O-CG1 3.45Å; I482-I486 PolarHBondContact O-N 3.5Å
483	L	87.3	Confident	85.5	Confident	38 Å²	38	60.4 Å²	60.4	20%	0.199	34%	0.344	C	S	.	.	H	α-helix	trans	-64.8	-43.5	177.7	179.4	63	0	0	0	112.7	V114 L118 L454 A479 G480 L485 I486 I487	V114-L483 HydrophobicContact CG1-CD1 3.81Å; V114-L483 HydrophobicContact CG1-CD2 3.52Å; V114-L483 HydrophobicContact CG1-CG 4.32Å; L118-L483 HydrophobicContact CD1-CD2 4.09Å; L118-L483 HydrophobicContact CD2-CD2 3.94Å; L118-L483 HydrophobicContact CG-CD2 4.08Å; L454-L483 HydrophobicContact CD1-CD2 4.36Å; L454-L483 HydrophobicContact CD1-CG 4.45Å; A479-L483 WeakPolarHBondContact O-CB 3.45Å; A479-L483 PolarHBondContact O-N 3.03Å; G480-L483 WeakPolarHBondContact O-CB 3.26Å; G480-L483 PolarHBondContact O-N 3.35Å; L483-L485 VanDerWaalsContact C-N 3.29Å; L483-L485 PolarHBondContact O-N 3.21Å; L483-I486 PolarHBondContact O-N 3.24Å; L483-I487 HydrophobicContact CD1-CD1 3.75Å; L483-I487 HydrophobicContact CD1-CG1 4.28Å; L483-I487 HydrophobicContact CG-CD1 3.98Å; L483-I487 WeakPolarHBondContact O-CG1 3.25Å; L483-I487 PolarHBondContact O-N 3.3Å
484	V	86.9	Confident	84.9	Confident	17 Å²	17	60.4 Å²	60.4	10%	0.103	33%	0.331	C	S	.	.	H	α-helix	trans	-52.4	-51.3	170.4	172.7	0	0	0	0	109.8	L454 I455 L458 G480 I487 C488	L454-V484 HydrophobicContact CD2-CB 4.08Å; L454-V484 HydrophobicContact CD2-CG2 3.4Å; L454-V484 VanDerWaalsContact CD2-CG2 3.4Å; I455-V484 HydrophobicContact CD1-CG1 4.18Å; I455-V484 HydrophobicContact CG1-CG1 3.78Å; I455-V484 HydrophobicContact CG1-CG2 4.43Å; L458-V484 HydrophobicContact CD2-CG2 3.63Å; G480-V484 VanDerWaalsContact O-CG2 3.3Å; G480-V484 WeakPolarHBondContact O-CG2 3.42Å; G480-V484 PolarHBondContact O-N 3.49Å; V484-I487 PolarHBondContact O-N 2.86Å; V484-C488 WeakPolarHBondContact O-CB 3.44Å; V484-C488 PolarHBondContact O-N 2.96Å; V484-C488 PolarHBondContact O-SG 3.48Å
485	L	87.8	Confident	84.4	Confident	111 Å²	111	55.2 Å²	55.2	58%	0.581	31%	0.305	S	S	*	.	H	α-helix	trans	-62.5	-46.8	-175.3	-173.9	153.1	0	0	0	111.3	G481 I482 L483 I487 C488 S489	G481-L485 WeakPolarHBondContact O-CB 3.48Å; G481-L485 PolarHBondContact O-N 2.99Å; I482-L485 PolarHBondContact O-N 3.45Å; L483-L485 VanDerWaalsContact C-N 3.29Å; L483-L485 PolarHBondContact O-N 3.21Å; L485-I487 PolarHBondContact O-N 2.97Å; L485-C488 PolarHBondContact O-N 3.37Å; L485-S489 WeakPolarHBondContact O-CB 3.46Å; L485-S489 PolarHBondContact O-N 2.87Å; L485-S489 PolarHBondContact O-OG 2.94Å; L485-S489 VanDerWaalsContact O-OG 3.07Å
486	I	86.9	Confident	84	Confident	84 Å²	84	55.3 Å²	55.3	43%	0.431	30%	0.295	S	S	.	.	H	α-helix	trans	-58.2	-50.1	177.3	-70.1	166.7	0	0	0	111	I482 L483 C488 S489 I490	I482-I486 HydrophobicContact CG2-CD1 3.78Å; I482-I486 HydrophobicContact CG2-CG1 4.45Å; I482-I486 WeakPolarHBondContact O-CG1 3.45Å; I482-I486 PolarHBondContact O-N 3.5Å; L483-I486 PolarHBondContact O-N 3.24Å; I486-C488 VanDerWaalsContact C-N 3.34Å; I486-C488 PolarHBondContact O-N 2.92Å; I486-S489 PolarHBondContact O-N 3.23Å; I486-I490 HydrophobicContact CG2-CD1 3.75Å; I486-I490 WeakPolarHBondContact O-CG1 3.06Å; I486-I490 PolarHBondContact O-N 3.15Å
487	I	84.1	Confident	83.5	Confident	5 Å²	5	53 Å²	53	3%	0.026	29%	0.29	C	S	.	.	H	α-helix	trans	-64.7	-38.8	-179.2	-70.1	170.1	0	0	0	111.2	L450 P451 L454 L483 V484 L485 N491	L450-I487 HydrophobicContact CB-CG2 3.81Å; L450-I487 HydrophobicContact CD1-CD1 4.49Å; L450-I487 HydrophobicContact CD1-CG2 4.02Å; P451-I487 HydrophobicContact CG-CG2 4.49Å; L454-I487 HydrophobicContact CD1-CD1 3.57Å; L483-I487 HydrophobicContact CD1-CD1 3.75Å; L483-I487 HydrophobicContact CD1-CG1 4.28Å; L483-I487 HydrophobicContact CG-CD1 3.98Å; L483-I487 WeakPolarHBondContact O-CG1 3.25Å; L483-I487 PolarHBondContact O-N 3.3Å; V484-I487 PolarHBondContact O-N 2.86Å; L485-I487 PolarHBondContact O-N 2.97Å; I487-N491 WeakPolarHBondContact O-CB 3.46Å; I487-N491 PolarHBondContact O-N 3.33Å; I487-N491 PolarHBondContact O-ND2 3.48Å
488	C	83.8	Confident	82.8	Confident	30 Å²	30	56.5 Å²	56.5	20%	0.203	30%	0.304	C	S	.	.	H	α-helix	trans	-68.6	-37.5	175.5	-65.4	0	0	0	0	112.2	V484 L485 I486 M492	V484-C488 WeakPolarHBondContact O-CB 3.44Å; V484-C488 PolarHBondContact O-N 2.96Å; V484-C488 PolarHBondContact O-SG 3.48Å; L485-C488 PolarHBondContact O-N 3.37Å; I486-C488 VanDerWaalsContact C-N 3.34Å; I486-C488 PolarHBondContact O-N 2.92Å; C488-M492 VanDerWaalsContact O-CB 3.27Å; C488-M492 WeakPolarHBondContact O-CB 3.44Å; C488-M492 PolarHBondContact O-N 3.23Å
489	S	85.1	Confident	82.1	Confident	67 Å²	67	52.5 Å²	52.5	47%	0.469	29%	0.285	S	S	.	.	H	α-helix	trans	-67.1	-39.8	175.4	-66.3	0	0	0	0	112.6	L485 I486 M492 Y493	L485-S489 WeakPolarHBondContact O-CB 3.46Å; L485-S489 PolarHBondContact O-N 2.87Å; L485-S489 PolarHBondContact O-OG 2.94Å; L485-S489 VanDerWaalsContact O-OG 3.07Å; I486-S489 PolarHBondContact O-N 3.23Å; S489-M492 PolarHBondContact O-N 3.17Å; S489-Y493 PolarHBondContact O-N 3.49Å; S489-Y493 VanDerWaalsContact O-N 3.12Å
490	I	81.1	Confident	81.4	Confident	49 Å²	49	56.5 Å²	56.5	25%	0.251	29%	0.294	S	S	.	.	H	α-helix	trans	-63.8	-49.9	174.7	-70.7	167.2	0	0	0	110.1	V257 I486 M492 Y493 F494	V257-I490 HydrophobicContact CB-CG2 4.24Å; V257-I490 HydrophobicContact CG1-CG2 3.42Å; V257-I490 VanDerWaalsContact CG1-CG2 3.42Å; V257-I490 HydrophobicContact CG2-CD1 4.48Å; V257-I490 HydrophobicContact CG2-CG2 3.72Å; I486-I490 HydrophobicContact CG2-CD1 3.75Å; I486-I490 WeakPolarHBondContact O-CG1 3.06Å; I486-I490 PolarHBondContact O-N 3.15Å; I490-M492 VanDerWaalsContact C-N 3.32Å; I490-M492 PolarHBondContact O-N 2.03Å; I490-Y493 WeakPolarHBondContact O-CB 3.27Å; I490-Y493 PolarHBondContact O-N 3.46Å; I490-Y493 VanDerWaalsContact O-N 3.08Å; I490-F494 HydrophobicContact CG2-CD2 4.15Å; I490-F494 HydrophobicContact CG2-CE2 4.26Å; I490-F494 PolarHBondContact O-N 3.33Å; I490-F494 VanDerWaalsContact O-N 3.07Å
491	N	81.8	Confident	80.7	Confident	2 Å²	2	63 Å²	63	1%	0.011	32%	0.321	C	S	.	.	H	α-helix	trans	-63.5	-35.6	178	-80.8	-51.3	0	0	0	113.2	S447 L448 I487 Y493 F494 V495	S447-N491 VanDerWaalsContact O-CG 3.32Å; S447-N491 PolarHBondContact O-ND2 2.99Å; S447-N491 PolarHBondContact O-OD1 3.06Å; S447-N491 VanDerWaalsContact O-OD1 3.09Å; L448-N491 WeakPolarHBondContact CA-OD1 3.35Å; L448-N491 HydrophobicContact CD2-CB 4.19Å; L448-N491 PolarHBondContact N-OD1 2.7Å; I487-N491 WeakPolarHBondContact O-CB 3.46Å; I487-N491 PolarHBondContact O-N 3.33Å; I487-N491 PolarHBondContact O-ND2 3.48Å; N491-Y493 VanDerWaalsContact C-N 3.3Å; N491-Y493 PolarHBondContact O-N 3.26Å; N491-F494 PolarHBondContact O-N 2.89Å; N491-V495 WeakPolarHBondContact O-CB 3.39Å; N491-V495 VanDerWaalsContact O-CG2 3.31Å; N491-V495 WeakPolarHBondContact O-CG2 3.43Å; N491-V495 PolarHBondContact O-N 3.3Å
492	M	79.2	Confident	80	Confident	86 Å²	86	64 Å²	64	42%	0.424	32%	0.321	S	S	.	.	H	α-helix	trans	-59.3	-41.1	171.9	-179.6	66.1	-169.9	0	0	111.8	C488 S489 I490 V496 L519	C488-M492 VanDerWaalsContact O-CB 3.27Å; C488-M492 WeakPolarHBondContact O-CB 3.44Å; C488-M492 PolarHBondContact O-N 3.23Å; S489-M492 PolarHBondContact O-N 3.17Å; I490-M492 VanDerWaalsContact C-N 3.32Å; I490-M492 PolarHBondContact O-N 2.03Å; M492-V496 HydrophobicContact CE-CG2 3.91Å; M492-V496 WeakPolarHBondContact O-CG2 3.34Å; M492-V496 PolarHBondContact O-N 3.19Å; M492-V496 VanDerWaalsContact O-N 3.13Å; M492-L519 HydrophobicContact CE-CD1 3.96Å; M492-L519 HydrophobicContact SD-CD1 3.43Å; M492-L519 WeakPolarHBondContact SD-CD1 3.43Å; M492-L519 HydrophobicContact SD-CD2 3.46Å; M492-L519 WeakPolarHBondContact SD-CD2 3.46Å; M492-L519 HydrophobicContact SD-CG 4.08Å
493	Y	81.9	Confident	78.9	Confident	131 Å²	131	63.3 Å²	63.3	51%	0.514	34%	0.337	S	S	.	.	H	α-helix	trans	-64.1	-48.8	175.8	174.5	-104.1	0	0	0	111.8	S489 I490 N491 V495 V496 V497	S489-Y493 PolarHBondContact O-N 3.49Å; S489-Y493 VanDerWaalsContact O-N 3.12Å; I490-Y493 WeakPolarHBondContact O-CB 3.27Å; I490-Y493 PolarHBondContact O-N 3.46Å; I490-Y493 VanDerWaalsContact O-N 3.08Å; N491-Y493 VanDerWaalsContact C-N 3.3Å; N491-Y493 PolarHBondContact O-N 3.26Å; Y493-V495 PolarHBondContact O-N 3.42Å; Y493-V496 PolarHBondContact O-N 2.84Å; Y493-V496 VanDerWaalsContact O-N 3.14Å; Y493-V497 HydrophobicContact CD1-CG2 4.38Å; Y493-V497 HydrophobicContact CD2-CG2 4.21Å; Y493-V497 HydrophobicContact CE1-CG2 3.96Å; Y493-V497 HydrophobicContact CE2-CG2 3.76Å; Y493-V497 WeakPolarHBondContact O-CG2 3.45Å; Y493-V497 PolarHBondContact O-N 3.06Å
494	F	73.9	Confident	78.6	Confident	43 Å²	43	68 Å²	68	19%	0.189	36%	0.358	C	S	.	.	H	α-helix	trans	-58.9	-43.4	177.6	-89.9	-95.5	0	0	0	112.7	V257 V444 I490 N491 V496 V497 Y498	V257-F494 HydrophobicContact CB-CE2 3.91Å; V257-F494 HydrophobicContact CB-CZ 4.15Å; V257-F494 HydrophobicContact CG1-CD2 4.28Å; V257-F494 HydrophobicContact CG1-CE2 3.56Å; V257-F494 HydrophobicContact CG1-CZ 3.98Å; V257-F494 HydrophobicContact CG2-CE2 4.11Å; V444-F494 HydrophobicContact CG1-CD1 4.17Å; V444-F494 HydrophobicContact CG2-CE1 4.45Å; I490-F494 HydrophobicContact CG2-CD2 4.15Å; I490-F494 HydrophobicContact CG2-CE2 4.26Å; I490-F494 PolarHBondContact O-N 3.33Å; I490-F494 VanDerWaalsContact O-N 3.07Å; N491-F494 PolarHBondContact O-N 2.89Å; F494-V496 VanDerWaalsContact C-N 3.33Å; F494-V496 PolarHBondContact O-N 2.93Å; F494-V497 PolarHBondContact O-N 3.3Å; F494-Y498 WeakPolarHBondContact O-CB 3.29Å; F494-Y498 PolarHBondContact O-N 3.34Å
495	V	75.7	Confident	78.2	Confident	16 Å²	16	73 Å²	73	10%	0.097	39%	0.387	C	S	.	.	H	α-helix	trans	-59.7	-42.5	175.2	168.5	0	0	0	0	111.6	L448 N491 Y493 V499 S515 Y518 L519	L448-V495 HydrophobicContact CD2-CG2 3.59Å; N491-V495 WeakPolarHBondContact O-CB 3.39Å; N491-V495 VanDerWaalsContact O-CG2 3.31Å; N491-V495 WeakPolarHBondContact O-CG2 3.43Å; N491-V495 PolarHBondContact O-N 3.3Å; Y493-V495 PolarHBondContact O-N 3.42Å; V495-V499 WeakPolarHBondContact O-CB 3.42Å; V495-V499 VanDerWaalsContact O-CG2 3.22Å; V495-V499 WeakPolarHBondContact O-CG2 3.26Å; V495-V499 PolarHBondContact O-N 3.39Å; V495-V499 VanDerWaalsContact O-N 3.13Å; V495-S515 WeakPolarHBondContact CG1-OG 3.48Å; V495-Y518 HydrophobicContact CG2-CD1 4.19Å; V495-Y518 HydrophobicContact CG2-CE1 3.93Å; V495-L519 HydrophobicContact CG1-CD1 4.44Å
496	V	77.1	Confident	77.9	Confident	58 Å²	58	71.2 Å²	71.2	35%	0.352	39%	0.389	S	S	.	.	H	α-helix	trans	-68	-42.9	178.9	170.1	0	0	0	0	112	M492 Y493 F494 Q500	M492-V496 HydrophobicContact CE-CG2 3.91Å; M492-V496 WeakPolarHBondContact O-CG2 3.34Å; M492-V496 PolarHBondContact O-N 3.19Å; M492-V496 VanDerWaalsContact O-N 3.13Å; Y493-V496 PolarHBondContact O-N 2.84Å; Y493-V496 VanDerWaalsContact O-N 3.14Å; F494-V496 VanDerWaalsContact C-N 3.33Å; F494-V496 PolarHBondContact O-N 2.93Å; V496-Q500 VanDerWaalsContact O-CG 3.29Å; V496-Q500 WeakPolarHBondContact O-CG 3.29Å; V496-Q500 PolarHBondContact O-N 2.99Å
497	V	76.4	Confident	77.5	Confident	44 Å²	44	71.7 Å²	71.7	27%	0.267	39%	0.392	S	S	.	.	H	α-helix	trans	-63.1	-51.8	177.7	173.4	0	0	0	0	110.6	Y493 F494 V499 Q500 E501	Y493-V497 HydrophobicContact CD1-CG2 4.38Å; Y493-V497 HydrophobicContact CD2-CG2 4.21Å; Y493-V497 HydrophobicContact CE1-CG2 3.96Å; Y493-V497 HydrophobicContact CE2-CG2 3.76Å; Y493-V497 WeakPolarHBondContact O-CG2 3.45Å; Y493-V497 PolarHBondContact O-N 3.06Å; F494-V497 PolarHBondContact O-N 3.3Å; V497-V499 VanDerWaalsContact C-N 3.3Å; V497-V499 PolarHBondContact O-N 3.27Å; V497-Q500 WeakPolarHBondContact O-CA 3.01Å; V497-Q500 WeakPolarHBondContact O-CB 3.42Å; V497-Q500 PolarHBondContact O-N 3.39Å; V497-E501 PolarHBondContact O-N 2.04Å
498	Y	70.9	Confident	77.4	Confident	123 Å²	123	76.6 Å²	76.6	48%	0.482	41%	0.411	S	S	.	.	H	α-helix	trans	-62.1	-35.9	-177.4	-167.3	-95.3	0	0	0	112.8	F441 F494 Q500 E501	F441-Y498 HydrophobicContact CE2-CE2 4.45Å; F494-Y498 WeakPolarHBondContact O-CB 3.29Å; F494-Y498 PolarHBondContact O-N 3.34Å; Y498-Q500 VanDerWaalsContact C-N 3.32Å; Y498-Q500 PolarHBondContact O-N 3.07Å; Y498-E501 PolarHBondContact O-N 3.27Å
499	V	72.8	Confident	77.4	Confident	15 Å²	15	79 Å²	79	9%	0.091	43%	0.425	C	S	.	.	H	α-helix	trans	-66.8	-32	173.4	169.2	0	0	0	0	112.1	V495 V497 Y508 A511 S515	V495-V499 WeakPolarHBondContact O-CB 3.42Å; V495-V499 VanDerWaalsContact O-CG2 3.22Å; V495-V499 WeakPolarHBondContact O-CG2 3.26Å; V495-V499 PolarHBondContact O-N 3.39Å; V495-V499 VanDerWaalsContact O-N 3.13Å; V497-V499 VanDerWaalsContact C-N 3.3Å; V497-V499 PolarHBondContact O-N 3.27Å; V499-Y508 HydrophobicContact CG1-CD2 3.99Å; V499-Y508 HydrophobicContact CG1-CE2 3.66Å; V499-Y508 WeakPolarHBondContact O-CD2 3.47Å; V499-Y508 WeakPolarHBondContact O-CE2 3.34Å; V499-A511 HydrophobicContact CG2-CB 4.14Å; V499-S515 WeakPolarHBondContact CG2-OG 3.43Å
500	Q	73.4	Confident	77.3	Confident	140 Å²	140	80.3 Å²	80.3	65%	0.654	43%	0.43	S	S	*	.	H	α-helix	trans	-75.1	-26.1	179.1	-73.4	173.2	5.2	0	0	113.7	V496 V497 Y498 L502	V496-Q500 VanDerWaalsContact O-CG 3.29Å; V496-Q500 WeakPolarHBondContact O-CG 3.29Å; V496-Q500 PolarHBondContact O-N 2.99Å; V497-Q500 WeakPolarHBondContact O-CA 3.01Å; V497-Q500 WeakPolarHBondContact O-CB 3.42Å; V497-Q500 PolarHBondContact O-N 3.39Å; Y498-Q500 VanDerWaalsContact C-N 3.32Å; Y498-Q500 PolarHBondContact O-N 3.07Å; Q500-L502 VanDerWaalsContact C-N 3.33Å
501	E	71.9	Confident	77.3	Confident	148 Å²	148	79 Å²	79	69%	0.692	43%	0.426	S	S	*	.	H	α-helix	trans	-79.1	-12.8	178.7	-65.8	-173.6	141.1	0	0	113.8	V497 Y498 G503	V497-E501 PolarHBondContact O-N 2.04Å; Y498-E501 PolarHBondContact O-N 3.27Å; E501-G503 PolarHBondContact O-N 3.43Å
502	L	72.2	Confident	77.4	Confident	44 Å²	44	80.3 Å²	80.3	23%	0.23	44%	0.437	C	S	.	.			trans	-73.6	82.3	-179.9	-70.1	171.4	0	0	0	112.6	Q500 H504 L507 A511	Q500-L502 VanDerWaalsContact C-N 3.33Å; L502-H504 PolarHBondContact O-N 3.02Å; L502-L507 HydrophobicContact CD2-CB 4.4Å; L502-A511 HydrophobicContact CD1-CB 3.28Å
503	G	67.7	Low	77.7	Confident	79 Å²	79	80.9 Å²	80.9	81%	0.814	45%	0.445	S	S	*	.			trans	-60.6	5.9	-179.3	0	0	0	0	0	117.7	E501	E501-G503 PolarHBondContact O-N 3.43Å
504	H	79.4	Confident	77.9	Confident	137 Å²	137	79 Å²	79	63%	0.634	45%	0.447	S	S	*	.	S	Bend	trans	-115.6	118.3	172.2	-75.4	-40.3	0	0	0	111.1	L502 A506 L507 Y508	L502-H504 PolarHBondContact O-N 3.02Å; H504-A506 PolarHBondContact O-N 3.33Å; H504-A506 VanDerWaalsContact O-N 3.08Å; H504-L507 HydrophobicContact CB-CB 4.31Å; H504-L507 HydrophobicContact CB-CD1 4.17Å; H504-L507 HydrophobicContact CB-CG 4.16Å; H504-L507 WeakPolarHBondContact O-CA 3.37Å; H504-L507 PolarHBondContact O-N 3.12Å; H504-Y508 PolarHBondContact O-N 2.96Å
505	V	79.6	Confident	78.4	Confident	120 Å²	120	77.9 Å²	77.9	73%	0.727	45%	0.445	S	S	*	.	H	α-helix	trans	-52.5	-36.2	-177	-176.2	0	0	0	0	113.3	Y508 V509	V505-Y508 PolarHBondContact O-N 3.17Å; V505-V509 WeakPolarHBondContact O-CG2 3.22Å; V505-V509 PolarHBondContact O-N 3.03Å
506	A	80.2	Confident	79	Confident	75 Å²	75	82.1 Å²	82.1	62%	0.62	47%	0.471	S	S	*	.	H	α-helix	trans	-66.6	-43.3	176.4	0	0	0	0	0	112.7	H504 V510	H504-A506 PolarHBondContact O-N 3.33Å; H504-A506 VanDerWaalsContact O-N 3.08Å; A506-V510 WeakPolarHBondContact O-CG2 3.35Å; A506-V510 PolarHBondContact O-N 2.85Å
507	L	79.1	Confident	79.6	Confident	93 Å²	93	82.4 Å²	82.4	49%	0.487	48%	0.479	S	S	.	.	H	α-helix	trans	-68.4	-40.4	175.2	-63.6	-179.4	0	0	0	111	L502 H504 V509 V510 A511	L502-L507 HydrophobicContact CD2-CB 4.4Å; H504-L507 HydrophobicContact CB-CB 4.31Å; H504-L507 HydrophobicContact CB-CD1 4.17Å; H504-L507 HydrophobicContact CB-CG 4.16Å; H504-L507 WeakPolarHBondContact O-CA 3.37Å; H504-L507 PolarHBondContact O-N 3.12Å; L507-V509 PolarHBondContact O-N 3.17Å; L507-V510 PolarHBondContact O-N 3.44Å; L507-A511 VanDerWaalsContact O-CB 3.24Å; L507-A511 WeakPolarHBondContact O-CB 3.5Å; L507-A511 PolarHBondContact O-N 3.13Å
508	Y	81.8	Confident	80.2	Confident	108 Å²	108	81.5 Å²	81.5	42%	0.424	47%	0.471	S	S	.	.	H	α-helix	trans	-55.6	-47.7	174.1	-178.8	-86.3	0	0	0	112	V499 H504 V505 A511 A512	V499-Y508 HydrophobicContact CG1-CD2 3.99Å; V499-Y508 HydrophobicContact CG1-CE2 3.66Å; V499-Y508 WeakPolarHBondContact O-CD2 3.47Å; V499-Y508 WeakPolarHBondContact O-CE2 3.34Å; H504-Y508 PolarHBondContact O-N 2.96Å; V505-Y508 PolarHBondContact O-N 3.17Å; Y508-A511 PolarHBondContact O-N 2.64Å; Y508-A512 WeakPolarHBondContact O-CB 3.38Å; Y508-A512 PolarHBondContact O-N 3Å
509	V	83.5	Confident	81.1	Confident	82 Å²	82	77.9 Å²	77.9	50%	0.497	46%	0.46	S	S	.	.	H	α-helix	trans	-64.2	-44.1	178.2	169.7	0	0	0	0	111.7	V505 L507 A512 V513	V505-V509 WeakPolarHBondContact O-CG2 3.22Å; V505-V509 PolarHBondContact O-N 3.03Å; L507-V509 PolarHBondContact O-N 3.17Å; V509-A512 PolarHBondContact O-N 3.2Å; V509-V513 WeakPolarHBondContact O-CG2 3.31Å; V509-V513 PolarHBondContact O-N 3.44Å
510	V	84.5	Confident	81.9	Confident	94 Å²	94	79.1 Å²	79.1	57%	0.57	48%	0.475	S	S	*	.	H	α-helix	trans	-63.8	-47.8	177.4	172.2	0	0	0	0	111.1	A506 L507 A512 V513 V514	A506-V510 WeakPolarHBondContact O-CG2 3.35Å; A506-V510 PolarHBondContact O-N 2.85Å; L507-V510 PolarHBondContact O-N 3.44Å; V510-A512 PolarHBondContact O-N 2.96Å; V510-V513 PolarHBondContact O-N 3.4Å; V510-V514 WeakPolarHBondContact O-CG2 3.38Å; V510-V514 PolarHBondContact O-N 3.38Å
511	A	81.4	Confident	82.8	Confident	20 Å²	20	73.3 Å²	73.3	17%	0.165	45%	0.448	C	S	.	.	H	α-helix	trans	-64.4	-39	179.3	0	0	0	0	0	112.1	V499 L502 L507 Y508 V514 S515	V499-A511 HydrophobicContact CG2-CB 4.14Å; L502-A511 HydrophobicContact CD1-CB 3.28Å; L507-A511 VanDerWaalsContact O-CB 3.24Å; L507-A511 WeakPolarHBondContact O-CB 3.5Å; L507-A511 PolarHBondContact O-N 3.13Å; Y508-A511 PolarHBondContact O-N 2.64Å; A511-V514 PolarHBondContact O-N 2.98Å; A511-S515 WeakPolarHBondContact O-CB 3.4Å; A511-S515 PolarHBondContact O-N 2.85Å; A511-S515 PolarHBondContact O-OG 3.1Å
512	A	82.1	Confident	83.6	Confident	30 Å²	30	67 Å²	67	25%	0.248	42%	0.419	C	S	.	.	H	α-helix	trans	-62.9	-41.8	174.3	0	0	0	0	0	112	Y508 V509 V510 S515 V516	Y508-A512 WeakPolarHBondContact O-CB 3.38Å; Y508-A512 PolarHBondContact O-N 3Å; V509-A512 PolarHBondContact O-N 3.2Å; V510-A512 PolarHBondContact O-N 2.96Å; A512-S515 PolarHBondContact O-N 3.49Å; A512-V516 WeakPolarHBondContact O-CG2 3.16Å; A512-V516 PolarHBondContact O-N 2.89Å
513	V	86.8	Confident	84.4	Confident	99 Å²	99	71.7 Å²	71.7	60%	0.6	44%	0.438	S	S	*	.	H	α-helix	trans	-64.7	-45.3	175.7	169.8	0	0	0	0	111.6	V509 V510 S515 V516 A517	V509-V513 WeakPolarHBondContact O-CG2 3.31Å; V509-V513 PolarHBondContact O-N 3.44Å; V510-V513 PolarHBondContact O-N 3.4Å; V513-S515 VanDerWaalsContact C-N 3.32Å; V513-S515 PolarHBondContact O-N 3.41Å; V513-V516 PolarHBondContact O-N 3.5Å; V513-A517 WeakPolarHBondContact O-CB 3.03Å; V513-A517 PolarHBondContact O-N 3.35Å
514	V	86.5	Confident	85.5	Confident	92 Å²	92	70.5 Å²	70.5	56%	0.558	41%	0.409	S	S	*	.	H	α-helix	trans	-61.7	-41.9	175.4	172	0	0	0	0	111	V510 A511 A517 Y518	V510-V514 WeakPolarHBondContact O-CG2 3.38Å; V510-V514 PolarHBondContact O-N 3.38Å; A511-V514 PolarHBondContact O-N 2.98Å; V514-A517 PolarHBondContact O-N 3.05Å; V514-Y518 WeakPolarHBondContact O-CB 3.12Å; V514-Y518 PolarHBondContact O-N 3.36Å
515	S	84.6	Confident	86	Confident	19 Å²	19	64 Å²	64	13%	0.133	38%	0.379	C	S	.	.	H	α-helix	trans	-62.9	-46	177.8	-61.9	0	0	0	0	112.1	V495 V499 A511 A512 V513 A517 Y518 L519	V495-S515 WeakPolarHBondContact CG1-OG 3.48Å; V499-S515 WeakPolarHBondContact CG2-OG 3.43Å; A511-S515 WeakPolarHBondContact O-CB 3.4Å; A511-S515 PolarHBondContact O-N 2.85Å; A511-S515 PolarHBondContact O-OG 3.1Å; A512-S515 PolarHBondContact O-N 3.49Å; V513-S515 VanDerWaalsContact C-N 3.32Å; V513-S515 PolarHBondContact O-N 3.41Å; S515-A517 VanDerWaalsContact C-N 3.32Å; S515-A517 PolarHBondContact O-N 3.3Å; S515-Y518 PolarHBondContact O-N 2.88Å; S515-L519 WeakPolarHBondContact O-CB 3.45Å; S515-L519 WeakPolarHBondContact O-CG 3.24Å; S515-L519 PolarHBondContact O-N 3.42Å
516	V	86.9	Confident	86.3	Confident	105 Å²	105	59 Å²	59	64%	0.636	35%	0.352	S	S	*	.	H	α-helix	trans	-63	-38.7	175.9	169.3	0	0	0	0	111.4	A512 V513 G520	A512-V516 WeakPolarHBondContact O-CG2 3.16Å; A512-V516 PolarHBondContact O-N 2.89Å; V513-V516 PolarHBondContact O-N 3.5Å; V516-G520 PolarHBondContact O-N 3.41Å
517	A	89.9	Confident	86.6	Confident	64 Å²	64	59.9 Å²	59.9	53%	0.529	34%	0.339	S	S	.	.	H	α-helix	trans	-66.2	-45.3	175.5	0	0	0	0	0	112.5	V513 V514 S515 F521	V513-A517 WeakPolarHBondContact O-CB 3.03Å; V513-A517 PolarHBondContact O-N 3.35Å; V514-A517 PolarHBondContact O-N 3.05Å; S515-A517 VanDerWaalsContact C-N 3.32Å; S515-A517 PolarHBondContact O-N 3.3Å; A517-F521 WeakPolarHBondContact O-CB 3.45Å; A517-F521 PolarHBondContact O-N 3.08Å
518	Y	89.9	Confident	86.9	Confident	24 Å²	24	56 Å²	56	9%	0.094	32%	0.319	C	S	.	.	H	α-helix	trans	-59.1	-52.4	174.5	162.8	-97.3	0	0	0	111.3	M152 L448 F452 V495 V514 S515 G520 F521 V522	M152-Y518 HydrophobicContact CE-CD2 4.49Å; L448-Y518 WeakPolarHBondContact O-CE2 3.17Å; L448-Y518 PolarHBondContact O-OH 3.47Å; L448-Y518 VanDerWaalsContact O-OH 3.07Å; F452-Y518 AromaticContact CE2-CD2 3.9Å; F452-Y518 HydrophobicContact CE2-CD2 3.9Å; F452-Y518 AromaticContact CE2-CE2 3.58Å; F452-Y518 HydrophobicContact CE2-CE2 3.58Å; F452-Y518 AromaticContact CZ-CD2 3.63Å; F452-Y518 HydrophobicContact CZ-CD2 3.63Å; F452-Y518 AromaticContact CZ-CE2 3.55Å; F452-Y518 HydrophobicContact CZ-CE2 3.55Å; V495-Y518 HydrophobicContact CG2-CD1 4.19Å; V495-Y518 HydrophobicContact CG2-CE1 3.93Å; V514-Y518 WeakPolarHBondContact O-CB 3.12Å; V514-Y518 PolarHBondContact O-N 3.36Å; S515-Y518 PolarHBondContact O-N 2.88Å; Y518-G520 PolarHBondContact O-N 2.95Å; Y518-F521 PolarHBondContact O-N 3.43Å; Y518-F521 VanDerWaalsContact O-N 3.12Å; Y518-V522 HydrophobicContact CD2-CG2 4.23Å; Y518-V522 HydrophobicContact CE1-CG2 4.3Å; Y518-V522 HydrophobicContact CE2-CG2 3.8Å; Y518-V522 WeakPolarHBondContact O-CG2 3.3Å; Y518-V522 PolarHBondContact O-N 2.97Å
519	L	88.1	Confident	87	Confident	48 Å²	48	51.1 Å²	51.1	25%	0.251	30%	0.3	S	S	.	.	H	α-helix	trans	-63.9	-39.6	-179.7	-68	170.8	0	0	0	112.2	M492 V495 S515 F521 V522 F523	M492-L519 HydrophobicContact CE-CD1 3.96Å; M492-L519 HydrophobicContact SD-CD1 3.43Å; M492-L519 WeakPolarHBondContact SD-CD1 3.43Å; M492-L519 HydrophobicContact SD-CD2 3.46Å; M492-L519 WeakPolarHBondContact SD-CD2 3.46Å; M492-L519 HydrophobicContact SD-CG 4.08Å; V495-L519 HydrophobicContact CG1-CD1 4.44Å; S515-L519 WeakPolarHBondContact O-CB 3.45Å; S515-L519 WeakPolarHBondContact O-CG 3.24Å; S515-L519 PolarHBondContact O-N 3.42Å; L519-F521 VanDerWaalsContact C-N 3.3Å; L519-F521 PolarHBondContact O-N 3.09Å; L519-V522 PolarHBondContact O-N 3.43Å; L519-F523 VanDerWaalsContact O-CB 3.27Å; L519-F523 WeakPolarHBondContact O-CB 3.38Å; L519-F523 PolarHBondContact O-N 3.36Å
520	G	90.2	Very high	87	Confident	40 Å²	40	50.3 Å²	50.3	41%	0.412	29%	0.293	S	S	.	.	H	α-helix	trans	-62	-36.9	173.5	0	0	0	0	0	112.7	V516 Y518 Y524	V516-G520 PolarHBondContact O-N 3.41Å; Y518-G520 PolarHBondContact O-N 2.95Å; G520-Y524 WeakPolarHBondContact O-CB 3.35Å; G520-Y524 PolarHBondContact O-N 3.05Å
521	F	91.8	Very high	86.8	Confident	19 Å²	19	48.3 Å²	48.3	8%	0.083	28%	0.278	C	S	.	.	H	α-helix	trans	-75	-40.7	176.9	-172.6	-125.5	0	0	0	112.9	P145 I148 L149 F452 A517 Y518 L519 F523 Y524 L525	P145-F521 HydrophobicContact CB-CE2 4.04Å; P145-F521 WeakPolarHBondContact O-CZ 3.27Å; I148-F521 HydrophobicContact CB-CE1 4.08Å; I148-F521 HydrophobicContact CB-CE2 4.28Å; I148-F521 HydrophobicContact CB-CZ 3.91Å; I148-F521 HydrophobicContact CG2-CD1 3.62Å; I148-F521 HydrophobicContact CG2-CD2 4.35Å; I148-F521 HydrophobicContact CG2-CE1 3.49Å; I148-F521 VanDerWaalsContact CG2-CE1 3.49Å; I148-F521 HydrophobicContact CG2-CE2 4.24Å; I148-F521 HydrophobicContact CG2-CG 4.08Å; I148-F521 HydrophobicContact CG2-CZ 3.82Å; L149-F521 HydrophobicContact CB-CE1 4.39Å; L149-F521 HydrophobicContact CB-CZ 4.06Å; F452-F521 HydrophobicContact CD1-CD1 4.13Å; F452-F521 AromaticContact CD1-CE1 3.95Å; F452-F521 HydrophobicContact CD1-CE1 3.95Å; F452-F521 AromaticContact CE1-CD1 3.37Å; F452-F521 HydrophobicContact CE1-CD1 3.37Å; F452-F521 AromaticContact CE1-CE1 3.68Å; F452-F521 HydrophobicContact CE1-CE1 3.68Å; F452-F521 HydrophobicContact CE1-CG 4.43Å; F452-F521 AromaticContact CZ-CD1 3.99Å; F452-F521 HydrophobicContact CZ-CD1 3.99Å; A517-F521 WeakPolarHBondContact O-CB 3.45Å; A517-F521 PolarHBondContact O-N 3.08Å; Y518-F521 PolarHBondContact O-N 3.43Å; Y518-F521 VanDerWaalsContact O-N 3.12Å; L519-F521 VanDerWaalsContact C-N 3.3Å; L519-F521 PolarHBondContact O-N 3.09Å; F521-F523 VanDerWaalsContact C-N 3.34Å; F521-Y524 HydrophobicContact CD2-CD1 4.24Å; F521-Y524 HydrophobicContact CE2-CD1 4.16Å; F521-Y524 PolarHBondContact O-N 3.06Å; F521-L525 HydrophobicContact CD1-CD1 4.37Å; F521-L525 HydrophobicContact CE1-CD1 3.87Å; F521-L525 HydrophobicContact CE2-CD1 4.4Å; F521-L525 HydrophobicContact CE2-CD2 4.41Å; F521-L525 HydrophobicContact CE2-CG 4.26Å; F521-L525 HydrophobicContact CZ-CD1 3.89Å; F521-L525 HydrophobicContact CZ-CD2 4.36Å; F521-L525 HydrophobicContact CZ-CG 4.22Å; F521-L525 WeakPolarHBondContact O-CG 3.29Å; F521-L525 PolarHBondContact O-N 2.95Å
522	V	90.1	Very high	86.6	Confident	14 Å²	14	47.8 Å²	47.8	9%	0.085	27%	0.274	C	S	.	.	H	α-helix	trans	-60.9	-43.1	171.3	173.5	0	0	0	0	110.7	P451 F452 I455 Y518 L519 L525 G526	P451-V522 HydrophobicContact CB-CG1 4.04Å; P451-V522 HydrophobicContact CB-CG2 4.18Å; P451-V522 HydrophobicContact CG-CG1 4.49Å; F452-V522 HydrophobicContact CE1-CG2 3.67Å; F452-V522 HydrophobicContact CZ-CG2 3.69Å; I455-V522 HydrophobicContact CD1-CG1 4.18Å; Y518-V522 HydrophobicContact CD2-CG2 4.23Å; Y518-V522 HydrophobicContact CE1-CG2 4.3Å; Y518-V522 HydrophobicContact CE2-CG2 3.8Å; Y518-V522 WeakPolarHBondContact O-CG2 3.3Å; Y518-V522 PolarHBondContact O-N 2.97Å; L519-V522 PolarHBondContact O-N 3.43Å; V522-L525 PolarHBondContact O-N 3.14Å; V522-G526 PolarHBondContact O-N 3.11Å
523	F	89.5	Confident	86.3	Confident	143 Å²	143	47.6 Å²	47.6	63%	0.627	27%	0.269	S	S	*	.	H	α-helix	trans	-62	-44.1	174.5	-179.6	-94.8	0	0	0	112	L519 F521 L525 G526 W527	L519-F523 VanDerWaalsContact O-CB 3.27Å; L519-F523 WeakPolarHBondContact O-CB 3.38Å; L519-F523 PolarHBondContact O-N 3.36Å; F521-F523 VanDerWaalsContact C-N 3.34Å; F523-L525 PolarHBondContact O-N 2.98Å; F523-G526 PolarHBondContact O-N 3.03Å; F523-W527 HydrophobicContact CZ-CE3 4.26Å; F523-W527 VanDerWaalsContact O-CB 3.32Å; F523-W527 WeakPolarHBondContact O-CB 3.19Å; F523-W527 PolarHBondContact O-N 3.44Å
524	Y	90.1	Very high	85.5	Confident	55 Å²	55	45 Å²	45	22%	0.216	26%	0.262	C	S	.	.	H	α-helix	trans	-58	-45.7	175.3	168.7	-92.8	0	0	0	112.4	P145 G520 F521 Q528 L546	P145-Y524 HydrophobicContact CB-CE1 3.84Å; P145-Y524 HydrophobicContact CG-CE1 3.76Å; G520-Y524 WeakPolarHBondContact O-CB 3.35Å; G520-Y524 PolarHBondContact O-N 3.05Å; F521-Y524 HydrophobicContact CD2-CD1 4.24Å; F521-Y524 HydrophobicContact CE2-CD1 4.16Å; F521-Y524 PolarHBondContact O-N 3.06Å; Y524-Q528 HydrophobicContact CE1-CG 4.45Å; Y524-Q528 WeakPolarHBondContact O-CG 3.29Å; Y524-Q528 PolarHBondContact O-N 2.9Å; Y524-L546 HydrophobicContact CE2-CD2 3.88Å
525	L	89.1	Confident	84.8	Confident	0 Å²	0	45.1 Å²	45.1	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-67.4	-42.7	176.8	-66.7	175	0	0	0	111.5	Y141 L149 F452 I455 F521 V522 F523 W527 Q528 C529	Y141-L525 HydrophobicContact CE1-CD2 3.98Å; Y141-L525 HydrophobicContact CE2-CD2 4.43Å; L149-L525 HydrophobicContact CD1-CD1 4.28Å; F452-L525 HydrophobicContact CD1-CD1 3.68Å; F452-L525 HydrophobicContact CE1-CD1 4.1Å; I455-L525 HydrophobicContact CB-CB 4.47Å; I455-L525 HydrophobicContact CD1-CB 4.39Å; I455-L525 HydrophobicContact CG2-CB 3.92Å; I455-L525 WeakPolarHBondContact CG2-O 3.48Å; F521-L525 HydrophobicContact CD1-CD1 4.37Å; F521-L525 HydrophobicContact CE1-CD1 3.87Å; F521-L525 HydrophobicContact CE2-CD1 4.4Å; F521-L525 HydrophobicContact CE2-CD2 4.41Å; F521-L525 HydrophobicContact CE2-CG 4.26Å; F521-L525 HydrophobicContact CZ-CD1 3.89Å; F521-L525 HydrophobicContact CZ-CD2 4.36Å; F521-L525 HydrophobicContact CZ-CG 4.22Å; F521-L525 WeakPolarHBondContact O-CG 3.29Å; F521-L525 PolarHBondContact O-N 2.95Å; V522-L525 PolarHBondContact O-N 3.14Å; F523-L525 PolarHBondContact O-N 2.98Å; L525-W527 VanDerWaalsContact C-N 3.32Å; L525-W527 PolarHBondContact O-N 2.68Å; L525-Q528 PolarHBondContact O-N 2.96Å; L525-C529 PolarHBondContact O-N 2.73Å
526	G	87.1	Confident	83.4	Confident	16 Å²	16	49.1 Å²	49.1	17%	0.165	29%	0.285	C	S	.	.	H	α-helix	trans	-59.8	-40.5	176.9	0	0	0	0	0	112.5	V522 F523 C529 L530	V522-G526 PolarHBondContact O-N 3.11Å; F523-G526 PolarHBondContact O-N 3.03Å; G526-C529 WeakPolarHBondContact O-CB 3.46Å; G526-C529 PolarHBondContact O-N 3.13Å; G526-L530 WeakPolarHBondContact O-CG 3.4Å; G526-L530 PolarHBondContact O-N 3.41Å
527	W	86.5	Confident	82	Confident	92 Å²	92	53 Å²	53	35%	0.348	29%	0.294	S	S	.	.	H	α-helix	trans	-59	-48.8	173.8	-179.6	-96.7	0	0	0	112.3	F523 L525 C529 L530 I531 L538	F523-W527 HydrophobicContact CZ-CE3 4.26Å; F523-W527 VanDerWaalsContact O-CB 3.32Å; F523-W527 WeakPolarHBondContact O-CB 3.19Å; F523-W527 PolarHBondContact O-N 3.44Å; L525-W527 VanDerWaalsContact C-N 3.32Å; L525-W527 PolarHBondContact O-N 2.68Å; W527-C529 VanDerWaalsContact C-N 3.27Å; W527-C529 PolarHBondContact O-N 2.8Å; W527-L530 PolarHBondContact O-N 3.04Å; W527-L530 VanDerWaalsContact O-N 3.16Å; W527-I531 PolarHBondContact O-N 3.29Å; W527-I531 VanDerWaalsContact O-N 3.11Å; W527-L538 HydrophobicContact CE3-CD1 4.11Å; W527-L538 HydrophobicContact CH2-CB 3.71Å; W527-L538 HydrophobicContact CH2-CD1 4.36Å; W527-L538 HydrophobicContact CH2-CD2 3.92Å; W527-L538 HydrophobicContact CH2-CG 4.19Å; W527-L538 HydrophobicContact CZ2-CB 3.97Å; W527-L538 WeakPolarHBondContact CZ2-O 3.16Å; W527-L538 HydrophobicContact CZ3-CB 4.11Å; W527-L538 HydrophobicContact CZ3-CD1 3.88Å; W527-L538 HydrophobicContact CZ3-CD2 3.83Å; W527-L538 HydrophobicContact CZ3-CG 4.15Å
528	Q	83.8	Confident	80.4	Confident	13 Å²	13	51.8 Å²	51.8	6%	0.061	28%	0.278	C	S	.	.	H	α-helix	trans	-60.6	-37.1	174.8	-63.7	-61.3	-31.7	0	0	111.9	Y524 L525 A532	Y524-Q528 HydrophobicContact CE1-CG 4.45Å; Y524-Q528 WeakPolarHBondContact O-CG 3.29Å; Y524-Q528 PolarHBondContact O-N 2.9Å; L525-Q528 PolarHBondContact O-N 2.96Å; Q528-A532 PolarHBondContact O-N 3.45Å; Q528-A532 VanDerWaalsContact O-N 3.07Å
529	C	85.3	Confident	78.7	Confident	4 Å²	4	56.1 Å²	56.1	3%	0.027	30%	0.303	C	S	.	.	H	α-helix	trans	-65.9	-41.4	174.3	-170.6	0	0	0	0	112.4	I455 T459 L525 G526 W527 I531 A532 L533	I455-C529 HydrophobicContact CG2-CB 3.63Å; T459-C529 WeakPolarHBondContact OG1-CA 3.4Å; T459-C529 VanDerWaalsContact OG1-CB 3.25Å; T459-C529 WeakPolarHBondContact OG1-CB 3.35Å; T459-C529 PolarHBondContact OG1-SG 2.77Å; L525-C529 PolarHBondContact O-N 2.73Å; G526-C529 WeakPolarHBondContact O-CB 3.46Å; G526-C529 PolarHBondContact O-N 3.13Å; W527-C529 VanDerWaalsContact C-N 3.27Å; W527-C529 PolarHBondContact O-N 2.8Å; C529-I531 VanDerWaalsContact C-N 3.32Å; C529-I531 PolarHBondContact O-N 3.36Å; C529-A532 PolarHBondContact O-N 3.23Å; C529-L533 WeakPolarHBondContact O-CB 3.32Å; C529-L533 WeakPolarHBondContact O-CG 3.38Å; C529-L533 PolarHBondContact O-N 3.18Å
530	L	83.3	Confident	76.3	Confident	65 Å²	65	59.7 Å²	59.7	34%	0.34	33%	0.331	S	S	.	.	H	α-helix	trans	-65	-35.6	178.5	-69.3	166.9	0	0	0	112.4	G526 W527 L533 G534 M535 L538	G526-L530 WeakPolarHBondContact O-CG 3.4Å; G526-L530 PolarHBondContact O-N 3.41Å; W527-L530 PolarHBondContact O-N 3.04Å; W527-L530 VanDerWaalsContact O-N 3.16Å; L530-L533 HydrophobicContact CD2-CD1 4.43Å; L530-L533 PolarHBondContact O-N 2.92Å; L530-G534 PolarHBondContact O-N 3.02Å; L530-M535 HydrophobicContact CD1-CE 4.38Å; L530-M535 VanDerWaalsContact O-N 3.11Å; L530-M535 PolarHBondContact O-N 3.48Å; L530-M535 HydrophobicContact CG-CE 4.42Å; L530-M535 HydrophobicContact CD2-CE 3.92Å; L530-M535 HydrophobicContact CB-CE 4.3Å; L530-L538 HydrophobicContact CB-CD1 3.79Å; L530-L538 HydrophobicContact CD1-CD1 4.13Å
531	I	80.8	Confident	73.9	Confident	52 Å²	52	60.4 Å²	60.4	27%	0.267	34%	0.339	S	S	.	.	H	α-helix	trans	-62.4	-50.8	170.3	-66.3	168.3	0	0	0	110	W527 C529 L533 G534	W527-I531 PolarHBondContact O-N 3.29Å; W527-I531 VanDerWaalsContact O-N 3.11Å; C529-I531 VanDerWaalsContact C-N 3.32Å; C529-I531 PolarHBondContact O-N 3.36Å; I531-L533 VanDerWaalsContact C-N 3.29Å; I531-L533 PolarHBondContact O-N 2.95Å; I531-G534 PolarHBondContact O-N 2.96Å; I531-G534 WeakPolarHBondContact O-CA 3.42Å
532	A	75.8	Confident	71.6	Confident	9 Å²	9	68.4 Å²	68.4	7%	0.074	38%	0.376	C	S	.	.	H	α-helix	trans	-62.1	-31.5	178.2	0	0	0	0	0	114.3	T459 L463 R477 Q528 C529 G534	T459-A532 HydrophobicContact CG2-CB 3.74Å; L463-A532 HydrophobicContact CD1-CB 4.36Å; L463-A532 HydrophobicContact CD2-CB 3.79Å; L463-A532 HydrophobicContact CG-CB 3.89Å; R477-A532 PolarHBondContact NH1-O 3.22Å; R477-A532 PolarHBondContact NH2-O 3.47Å; Q528-A532 PolarHBondContact O-N 3.45Å; Q528-A532 VanDerWaalsContact O-N 3.07Å; C529-A532 PolarHBondContact O-N 3.23Å; A532-G534 PolarHBondContact O-N 2.94Å
533	L	77.1	Confident	68.9	Low	27 Å²	27	74.7 Å²	74.7	14%	0.141	42%	0.415	C	S	.	.	H	α-helix	trans	-72.2	-13.5	173.5	-70.7	167.9	0	0	0	112.8	L458 R477 C529 L530 I531	L458-L533 HydrophobicContact CD2-CD1 4.26Å; L458-L533 HydrophobicContact CD2-CD2 4.33Å; L458-L533 HydrophobicContact CG-CD2 4.3Å; R477-L533 HydrophobicContact CB-CD2 3.62Å; R477-L533 HydrophobicContact CG-CD2 3.83Å; R477-L533 PolarHBondContact NH1-O 3.03Å; C529-L533 WeakPolarHBondContact O-CB 3.32Å; C529-L533 WeakPolarHBondContact O-CG 3.38Å; C529-L533 PolarHBondContact O-N 3.18Å; L530-L533 HydrophobicContact CD2-CD1 4.43Å; L530-L533 PolarHBondContact O-N 2.92Å; I531-L533 VanDerWaalsContact C-N 3.29Å; I531-L533 PolarHBondContact O-N 2.95Å
534	G	70	Confident	66.1	Low	44 Å²	44	72.5 Å²	72.5	45%	0.454	42%	0.416	S	S	.	.	T	Hydrogen-bonded Turn	trans	105.1	20	169.3	0	0	0	0	0	115.6	L530 I531 A532 S536	L530-G534 PolarHBondContact O-N 3.02Å; I531-G534 PolarHBondContact O-N 2.96Å; I531-G534 WeakPolarHBondContact O-CA 3.42Å; A532-G534 PolarHBondContact O-N 2.94Å; G534-S536 VanDerWaalsContact C-N 3.28Å; G534-S536 PolarHBondContact O-N 3.14Å
535	M	71.4	Confident	63.4	Low	95 Å²	95	78.2 Å²	78.2	47%	0.468	44%	0.444	S	S	.	.			trans	-82.4	68.6	177.7	-58.1	-138.1	-50	0	0	111.9	L530 F537 L538	L530-M535 HydrophobicContact CD1-CE 4.38Å; L530-M535 VanDerWaalsContact O-N 3.11Å; L530-M535 PolarHBondContact O-N 3.48Å; L530-M535 HydrophobicContact CG-CE 4.42Å; L530-M535 HydrophobicContact CD2-CE 3.92Å; L530-M535 HydrophobicContact CB-CE 4.3Å; M535-F537 PolarHBondContact O-N 3.22Å; M535-L538 HydrophobicContact CB-CD1 4.22Å; M535-L538 HydrophobicContact CB-CG 4.24Å; M535-L538 HydrophobicContact CE-CD1 3.69Å; M535-L538 HydrophobicContact CE-CG 4.27Å; M535-L538 WeakPolarHBondContact O-CB 3.46Å; M535-L538 PolarHBondContact O-N 2.9Å
536	S	55.7	Low	60.8	Low	102 Å²	102	81 Å²	81	71%	0.713	46%	0.458	S	S	*	.	G	3₁₀ helix	trans	-57	-20	-171.7	-43.6	0	0	0	0	115.6	G534 L538 D539	G534-S536 VanDerWaalsContact C-N 3.28Å; G534-S536 PolarHBondContact O-N 3.14Å; S536-L538 PolarHBondContact O-N 3.03Å; S536-D539 WeakPolarHBondContact O-CB 3.5Å; S536-D539 PolarHBondContact O-N 3.5Å; S536-D539 VanDerWaalsContact O-N 3.12Å
537	F	56.7	Low	58.4	Low	188 Å²	188	81.9 Å²	81.9	83%	0.825	47%	0.468	S	S	*	.	G	3₁₀ helix	trans	-63.9	-20.6	173.5	-175.5	-104.2	0	0	0	113.2	M535 D539	M535-F537 PolarHBondContact O-N 3.22Å; F537-D539 VanDerWaalsContact C-N 3.32Å
538	L	57.2	Low	56.3	Low	37 Å²	37	79.4 Å²	79.4	19%	0.194	46%	0.461	C	S	.	.	G	3₁₀ helix	trans	-79.2	-11.1	175	-58.8	-172.1	0	0	0	113.4	W527 L530 M535 S536 C540	W527-L538 HydrophobicContact CE3-CD1 4.11Å; W527-L538 HydrophobicContact CH2-CB 3.71Å; W527-L538 HydrophobicContact CH2-CD1 4.36Å; W527-L538 HydrophobicContact CH2-CD2 3.92Å; W527-L538 HydrophobicContact CH2-CG 4.19Å; W527-L538 HydrophobicContact CZ2-CB 3.97Å; W527-L538 WeakPolarHBondContact CZ2-O 3.16Å; W527-L538 HydrophobicContact CZ3-CB 4.11Å; W527-L538 HydrophobicContact CZ3-CD1 3.88Å; W527-L538 HydrophobicContact CZ3-CD2 3.83Å; W527-L538 HydrophobicContact CZ3-CG 4.15Å; L530-L538 HydrophobicContact CB-CD1 3.79Å; L530-L538 HydrophobicContact CD1-CD1 4.13Å; M535-L538 HydrophobicContact CB-CD1 4.22Å; M535-L538 HydrophobicContact CB-CG 4.24Å; M535-L538 HydrophobicContact CE-CD1 3.69Å; M535-L538 HydrophobicContact CE-CG 4.27Å; M535-L538 WeakPolarHBondContact O-CB 3.46Å; M535-L538 PolarHBondContact O-N 2.9Å; S536-L538 PolarHBondContact O-N 3.03Å; L538-C540 PolarHBondContact O-N 2.8Å
539	D	52.7	Low	54.1	Low	116 Å²	116	84.1 Å²	84.1	62%	0.62	49%	0.491	S	S	*	.			trans	-77.5	26.4	179.9	-156	22.7	0	0	0	113.1	S536 F537 G541	S536-D539 WeakPolarHBondContact O-CB 3.5Å; S536-D539 PolarHBondContact O-N 3.5Å; S536-D539 VanDerWaalsContact O-N 3.12Å; F537-D539 VanDerWaalsContact C-N 3.32Å; D539-G541 VanDerWaalsContact C-N 3.28Å; D539-G541 PolarHBondContact O-N 2.92Å
540	C	39.2	Very low	51.7	Low	122 Å²	122	86.5 Å²	86.5	82%	0.824	51%	0.511	S	S	*	.			trans	-85.7	62.3	-171.1	-149.9	0	0	0	0	111.1	L538	L538-C540 PolarHBondContact O-N 2.8Å
541	G	39.1	Very low	49.4	Very low	56 Å²	56	88.9 Å²	88.9	58%	0.577	52%	0.52	S	S	*	.			trans	-168.6	53	-170.9	0	0	0	0	0	115.5	D539 T543	D539-G541 VanDerWaalsContact C-N 3.28Å; D539-G541 PolarHBondContact O-N 2.92Å; G541-T543 PolarHBondContact O-N 3.32Å
542	H	42.3	Very low	47.4	Very low	186 Å²	186	90.7 Å²	90.7	86%	0.861	54%	0.535	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.5	45	-168.3	-154.3	-60.9	0	0	0	116.1
543	T	33.4	Very low	45.5	Very low	147 Å²	147	97.2 Å²	97.2	90%	0.902	56%	0.564	S	S	*	*	T	Hydrogen-bonded Turn	trans	-149.1	29	175.5	13.9	0	0	0	0	115.2	G541	G541-T543 PolarHBondContact O-N 3.32Å
544	C	31.1	Very low	43.4	Very low	97 Å²	97	99.4 Å²	99.4	66%	0.655	58%	0.576	S	S	*	*			trans	-138.4	115.9	166.1	-154.8	0	0	0	0	112	L546	C544-L546 HydrophobicContact CB-CD1 4.05Å; C544-L546 VanDerWaalsContact SG-CD1 3.51Å; C544-L546 PolarHBondContact O-N 3.48Å
545	H	34.7	Very low	41.8	Very low	174 Å²	174	102.1 Å²	102.1	81%	0.806	57%	0.573	S	S	*	*			trans	-76.1	67.7	-176.3	-116.3	-69.7	0	0	0	111.7
546	L	34	Very low	40.1	Very low	58 Å²	58	103.2 Å²	103.2	30%	0.304	58%	0.58	S	S	.	*			trans	-74.9	129	169.5	-91.2	68.6	0	0	0	109.7	Y524 C544 L548	Y524-L546 HydrophobicContact CE2-CD2 3.88Å; C544-L546 HydrophobicContact CB-CD1 4.05Å; C544-L546 VanDerWaalsContact SG-CD1 3.51Å; C544-L546 PolarHBondContact O-N 3.48Å; L546-L548 PolarHBondContact O-N 3.29Å
547	G	36.2	Very low	39	Very low	35 Å²	35	102.7 Å²	102.7	36%	0.361	57%	0.569	S	S	.	*	G	3₁₀ helix	trans	-66	-0.9	-159	0	0	0	0	0	118.7	T549 A550	G547-T549 VanDerWaalsContact O-N 3.1Å; G547-T549 PolarHBondContact O-N 2.95Å; G547-A550 PolarHBondContact O-N 3.34Å; G547-A550 VanDerWaalsContact O-N 3.16Å
548	L	41.9	Very low	37.9	Very low	40 Å²	40	98.5 Å²	98.5	21%	0.209	56%	0.555	C	S	.	*	G	3₁₀ helix	trans	-60	-22.5	-176.9	-97.2	76.8	0	0	0	114.1	L546	L546-L548 PolarHBondContact O-N 3.29Å
549	T	38.9	Very low	36.9	Very low	113 Å²	113	99.2 Å²	99.2	69%	0.693	57%	0.566	S	S	*	*	G	3₁₀ helix	trans	-113.7	-1.4	179.6	51.9	0	0	0	0	113.6	G547 Q551	G547-T549 VanDerWaalsContact O-N 3.1Å; G547-T549 PolarHBondContact O-N 2.95Å; T549-Q551 PolarHBondContact O-N 3.3Å
550	A	34.3	Very low	36	Very low	53 Å²	53	99.7 Å²	99.7	44%	0.438	57%	0.566	S	S	.	*	S	Bend	trans	-78.7	-19.7	-163.9	0	0	0	0	0	115.3	G547	G547-A550 PolarHBondContact O-N 3.34Å; G547-A550 VanDerWaalsContact O-N 3.16Å
551	Q	35.3	Very low	35.7	Very low	116 Å²	116	98.8 Å²	98.8	54%	0.542	55%	0.553	S	S	.	*			trans	-142.9	79.9	178.1	-71.3	-164.2	-50.3	0	0	114.4	T549 E553 L554	T549-Q551 PolarHBondContact O-N 3.3Å; Q551-E553 VanDerWaalsContact C-N 3.29Å; Q551-L554 HydrophobicContact CB-CB 3.97Å; Q551-L554 HydrophobicContact CG-CB 4.46Å
552	P	39.4	Very low	35.5	Very low	89 Å²	89	98.8 Å²	98.8	58%	0.578	55%	0.548	S	S	*	.	S	Bend	trans	-64.4	-37.1	154.7	-15.1	30.6	0	0	0	111.1	L554 Y555	P552-L554 PolarHBondContact O-N 3.23Å; P552-Y555 PolarHBondContact O-N 3.24Å
553	E	34.6	Very low	35.1	Very low	147 Å²	147	95.8 Å²	95.8	69%	0.687	54%	0.538	S	S	*	.	H	α-helix	trans	-70.6	-27.9	-170.6	-60.7	-171.3	148.9	0	0	114.1	Q551 Y555 L556 L557	Q551-E553 VanDerWaalsContact C-N 3.29Å; E553-Y555 PolarHBondContact O-N 2.85Å; E553-L556 PolarHBondContact O-N 3.35Å; E553-L557 PolarHBondContact O-N 3.49Å
554	L	34	Very low	34.8	Very low	73 Å²	73	91.7 Å²	91.7	38%	0.382	52%	0.516	S	S	.	.	H	α-helix	trans	-65.4	-23.9	176.4	-158.1	82.7	0	0	0	111.9	Q551 P552 N558	Q551-L554 HydrophobicContact CB-CB 3.97Å; Q551-L554 HydrophobicContact CG-CB 4.46Å; P552-L554 PolarHBondContact O-N 3.23Å; L554-N558 PolarHBondContact O-N 3.46Å; L554-N558 PolarHBondContact O-ND2 2.92Å
555	Y	36.3	Very low	34.7	Very low	101 Å²	101	94.4 Å²	94.4	40%	0.396	52%	0.523	S	S	.	.	H	α-helix	trans	-78.2	-26.8	172.7	-76.9	-92.6	0	0	0	113	Q140 P552 E553	Q140-Y555 PolarHBondContact NE2-OH 2.99Å; P552-Y555 PolarHBondContact O-N 3.24Å; E553-Y555 PolarHBondContact O-N 2.85Å
556	L	34.8	Very low	34.7	Very low	117 Å²	117	92.2 Å²	92.2	61%	0.613	52%	0.521	S	S	*	.	H	α-helix	trans	-74.3	-43.8	169.2	-93.8	121.8	0	0	0	111.5	E553 N558 A559 M560	E553-L556 PolarHBondContact O-N 3.35Å; L556-N558 PolarHBondContact O-N 3.09Å; L556-A559 WeakPolarHBondContact O-CB 3.16Å; L556-A559 PolarHBondContact O-N 3.05Å; L556-M560 PolarHBondContact O-N 2.77Å
557	L	32.1	Very low	34.6	Very low	92 Å²	92	93.7 Å²	93.7	48%	0.482	54%	0.536	S	S	.	.	H	α-helix	trans	-61.1	-42.8	179.4	-77.3	164.4	0	0	0	112.4	E553 A559 M560 D561	E553-L557 PolarHBondContact O-N 3.49Å; L557-A559 PolarHBondContact O-N 3.04Å; L557-M560 PolarHBondContact O-N 2.78Å; L557-M560 VanDerWaalsContact O-N 3.12Å; L557-D561 PolarHBondContact O-N 3Å
558	N	34.3	Very low	34.3	Very low	100 Å²	100	107 Å²	107	54%	0.535	58%	0.576	S	S	.	*	H	α-helix	trans	-67.7	-15.8	175.4	-80.6	-94.5	0	0	0	113.9	L554 L556	L554-N558 PolarHBondContact O-N 3.46Å; L554-N558 PolarHBondContact O-ND2 2.92Å; L556-N558 PolarHBondContact O-N 3.09Å
559	A	36.7	Very low	33.9	Very low	52 Å²	52	110.3 Å²	110.3	43%	0.43	59%	0.594	S	S	.	*	H	α-helix	trans	-81.3	-42.5	168.8	0	0	0	0	0	110.9	L556 L557 D561 A562 D563	L556-A559 WeakPolarHBondContact O-CB 3.16Å; L556-A559 PolarHBondContact O-N 3.05Å; L557-A559 PolarHBondContact O-N 3.04Å; A559-D561 PolarHBondContact O-N 3.17Å; A559-A562 WeakPolarHBondContact O-CB 3.43Å; A559-A562 PolarHBondContact O-N 2.78Å; A559-A562 VanDerWaalsContact O-N 3.13Å; A559-D563 PolarHBondContact O-N 3.01Å
560	M	33.8	Very low	33.6	Very low	126 Å²	126	110.2 Å²	110.2	62%	0.621	59%	0.589	S	S	*	*	H	α-helix	trans	-65.1	-36.1	177.6	-65.3	-177.6	70.7	0	0	113.1	L556 L557 A562 D563 S564	L556-M560 PolarHBondContact O-N 2.77Å; L557-M560 PolarHBondContact O-N 2.78Å; L557-M560 VanDerWaalsContact O-N 3.12Å; M560-A562 VanDerWaalsContact C-N 3.25Å; M560-A562 PolarHBondContact O-N 3.09Å; M560-D563 PolarHBondContact O-N 2.86Å; M560-S564 WeakPolarHBondContact O-CB 3.15Å; M560-S564 PolarHBondContact O-N 2.84Å
561	D	32	Very low	33.6	Very low	102 Å²	102	113.3 Å²	113.3	55%	0.545	60%	0.597	S	S	.	*	H	α-helix	trans	-73.5	-13.8	174.6	-78.1	-29.2	0	0	0	113.7	L557 A559 S564	L557-D561 PolarHBondContact O-N 3Å; A559-D561 PolarHBondContact O-N 3.17Å; D561-S564 PolarHBondContact O-OG 3.47Å
562	A	34.5	Very low	33.5	Very low	57 Å²	57	113.2 Å²	113.2	47%	0.471	60%	0.6	S	S	.	*	H	α-helix	trans	-80.9	-42.2	170.2	0	0	0	0	0	111.4	A559 M560	A559-A562 WeakPolarHBondContact O-CB 3.43Å; A559-A562 PolarHBondContact O-N 2.78Å; A559-A562 VanDerWaalsContact O-N 3.13Å; M560-A562 VanDerWaalsContact C-N 3.25Å; M560-A562 PolarHBondContact O-N 3.09Å
563	D	34.1	Very low	33.1	Very low	122 Å²	122	114.7 Å²	114.7	65%	0.652	60%	0.602	S	S	*	*	H	α-helix	trans	-72	-30.7	177.6	-71.8	-29.3	0	0	0	112.6	A559 M560 L565 V566 S567	A559-D563 PolarHBondContact O-N 3.01Å; M560-D563 PolarHBondContact O-N 2.86Å; D563-L565 VanDerWaalsContact C-N 3.29Å; D563-L565 PolarHBondContact O-N 3.41Å; D563-V566 PolarHBondContact O-N 3.05Å; D563-S567 PolarHBondContact O-OG 2.94Å
564	S	27.8	Very low	33.1	Very low	61 Å²	61	112.5 Å²	112.5	43%	0.427	60%	0.596	S	S	.	*	G	3₁₀ helix	trans	-69	-24.1	179.8	75	0	0	0	0	113.8	M560 D561	M560-S564 WeakPolarHBondContact O-CB 3.15Å; M560-S564 PolarHBondContact O-N 2.84Å; D561-S564 PolarHBondContact O-OG 3.47Å
565	L	29.5	Very low	33	Very low	154 Å²	154	115.4 Å²	115.4	81%	0.806	61%	0.611	S	S	*	*	G	3₁₀ helix	trans	-86.6	-1.8	177.7	-80.1	168.7	0	0	0	114.4	D563	D563-L565 VanDerWaalsContact C-N 3.29Å; D563-L565 PolarHBondContact O-N 3.41Å
566	V	34.6	Very low	32.7	Very low	128 Å²	128	116.5 Å²	116.5	78%	0.776	63%	0.628	S	S	*	*	G	3₁₀ helix	trans	-102	0.6	175.3	-175.6	0	0	0	0	111.7	D563	D563-V566 PolarHBondContact O-N 3.05Å
567	S	32	Very low	32.6	Very low	89 Å²	89	116.4 Å²	116.4	62%	0.622	63%	0.629	S	S	*	*			trans	-137.5	52.8	-173.3	53.7	0	0	0	0	114.9	D563	D563-S567 PolarHBondContact O-OG 2.94Å
568	R	29.3	Very low	32.6	Very low	314 Å²	314	118.6 Å²	118.6	100%	1.185	64%	0.643	S	S	*	*			trans	-152.7	0	162.9	-116.2	171.8	-168.3	-176.2	3.5	114

Retrieved 568 of 568 residues in 197.1 ms (Link to these results)

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