A0A2K5XVC0_MANLE Loading...

Ezrin

AlphaFold DB , UniProt , Accession A0A2K5XVC0, Species MANLE (Mandrillus leucophaeus, Drill), Gene EZR, Length 586 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M68.3Low91Very high232 Ų23273.4 Ų73.4100%1.14338%0.376SS*.  0153.50-59.4175.9-171.600108.8
2P74.4Confident91.5Very high89 Ų8970.6 Ų70.658%0.57836%0.361SS*.PPolyproline II helixtrans-59145.8165.8-16.530.5000109.9P22P2-P22 HydrophobicContact CB-CG 4.01Å
3K85.9Confident91.5Very high181 Ų18170.2 Ų70.279%0.78736%0.36SS*.PPolyproline II helixtrans-77.1133.4169.1-70.8-171.3177-174.70108.9P22K3-P22 VanDerWaalsContact O-CG 3.29Å; K3-P22 WeakPolarHBondContact O-CG 3.27Å
4P92.3Very high91.7Very high76 Ų7668.1 Ų68.149%0.49436%0.359SS..PPolyproline II helixtrans-63.6155.6171.426.9-33.2000110.9A19P4-A19 HydrophobicContact CB-CB 4Å
5I94.6Very high92.1Very high44 Ų4470.5 Ų70.523%0.22637%0.367CS..EExtended strand (participates in β ladder)trans-113.2117.2175-57174.8000107.2A19 I20 P22 L76I5-A19 WeakPolarHBondContact O-CA 3.17Å; I5-I20 HydrophobicContact CB-CG1 3.92Å; I5-I20 HydrophobicContact CG2-CG1 4.39Å; I5-I20 PolarHBondContact N-O 3.3Å; I5-I20 PolarHBondContact O-N 2.72Å; I5-P22 HydrophobicContact CD1-CB 4.29Å; I5-P22 HydrophobicContact CD1-CG 4.29Å; I5-P22 HydrophobicContact CG1-CG 4.43Å; I5-L76 HydrophobicContact CG2-CD1 3.53Å; I5-L76 HydrophobicContact CG2-CG 3.97Å
6N96.6Very high92.3Very high76 Ų7667.9 Ų67.941%0.40635%0.353SS..EExtended strand (participates in β ladder)trans-74.4138.8176.9-57-30.4000110.1N74 P75 L76N6-N74 WeakPolarHBondContact CB-OD1 3.31Å; N6-N74 PolarHBondContact ND2-OD1 3.48Å; N6-P75 HydrophobicContact CB-CB 3.89Å; N6-P75 WeakPolarHBondContact O-CA 3.21Å; N6-L76 PolarHBondContact O-N 2.84Å
7V97.3Very high92.5Very high1 Ų170.6 Ų70.61%0.00636%0.364CS..EExtended strand (participates in β ladder)trans-132.5137.1-178.6-179.20000109.2V9 E17 F18 I20 L29 L76 F78V7-V9 HydrophobicContact CG1-CG2 3.97Å; V7-E17 WeakPolarHBondContact O-CA 3.47Å; V7-F18 PolarHBondContact N-O 2.96Å; V7-F18 PolarHBondContact O-N 2.83Å; V7-I20 HydrophobicContact CG2-CB 4.42Å; V7-I20 HydrophobicContact CG2-CD1 3.76Å; V7-I20 HydrophobicContact CG2-CG1 3.73Å; V7-I20 HydrophobicContact CG2-CG2 3.95Å; V7-L29 HydrophobicContact CG1-CD1 4.06Å; V7-L29 HydrophobicContact CG1-CD2 4.38Å; V7-L76 HydrophobicContact CG2-CB 4.45Å; V7-F78 HydrophobicContact CG1-CD2 3.53Å; V7-F78 HydrophobicContact CG1-CE2 3.69Å
8R98.2Very high92.6Very high72 Ų7269.7 Ų69.727%0.27236%0.357SS..EExtended strand (participates in β ladder)trans-112.6131.9166.7-176.9-178.8-64-162.95.5108.9E15 L16 E17 P75 L76 F78R8-E15 WeakPolarHBondContact CD-OE2 3.45Å; R8-E15 IonicContact CZ-OE2 3.77Å; R8-E15 IonicContact NE-OE2 2.6Å; R8-E15 IonicContact NH1-OE2 3.59Å; R8-E15 PolarHBondContact NH1-OE2 3.17Å; R8-L16 CarbonylContact C-O 3.57Å; R8-L16 WeakPolarHBondContact CA-O 3.16Å; R8-E17 HydrophobicContact CB-CG 4.17Å; R8-E17 HydrophobicContact CG-CG 4.08Å; R8-E17 IonicContact CZ-OE1 3.64Å; R8-E17 IonicContact NE-OE1 2.79Å; R8-E17 PolarHBondContact NE-OE1 3.11Å; R8-E17 IonicContact NH2-OE1 3.63Å; R8-E17 PolarHBondContact NH2-OE1 3.38Å; R8-P75 HydrophobicContact CB-CB 4.18Å; R8-P75 HydrophobicContact CB-CG 3.81Å; R8-L76 PolarHBondContact N-O 3.05Å; R8-F78 PolarHBondContact O-N 2.8Å
9V98.3Very high92.8Very high0 Ų069.3 Ų69.30%037%0.365CS..EExtended strand (participates in β ladder)trans-121.5110173.3-173.60000109.3V7 L16 F18 L29 V33 L47 F78 F80V7-V9 HydrophobicContact CG1-CG2 3.97Å; V9-L16 HydrophobicContact CB-CB 4.44Å; V9-L16 PolarHBondContact N-O 3.23Å; V9-L16 PolarHBondContact O-N 3.08Å; V9-F18 HydrophobicContact CG2-CE1 4.27Å; V9-F18 HydrophobicContact CG2-CZ 4.2Å; V9-L29 HydrophobicContact CG2-CD1 4.4Å; V9-V33 HydrophobicContact CB-CG2 4.04Å; V9-V33 HydrophobicContact CG1-CG1 4.1Å; V9-V33 HydrophobicContact CG1-CG2 3.85Å; V9-V33 HydrophobicContact CG2-CG2 3.77Å; V9-L47 HydrophobicContact CG1-CD2 3.45Å; V9-L47 VanDerWaalsContact CG1-CD2 3.45Å; V9-L47 HydrophobicContact CG2-CD2 4.37Å; V9-F78 WeakPolarHBondContact CA-O 3.33Å; V9-F78 HydrophobicContact CG2-CB 4.31Å; V9-F80 HydrophobicContact CG1-CB 3.92Å
10T98.2Very high92.9Very high35 Ų3566.3 Ų66.322%0.21535%0.349CS..EExtended strand (participates in β ladder)trans-92.4120.8176.1-48.10000109.3E15 F78 K79 F80T10-E15 HydrophobicContact CG2-CG 4.14Å; T10-E15 WeakPolarHBondContact CG2-OE1 3.49Å; T10-E15 PolarHBondContact OG1-OE1 2.74Å; T10-F78 PolarHBondContact N-O 3.31Å; T10-K79 CarbonylContact O-C 3.57Å; T10-K79 WeakPolarHBondContact O-CA 3.49Å; T10-F80 PolarHBondContact O-N 2.92Å
11T97.3Very high93Very high1 Ų167.6 Ų67.61%0.00635%0.354CS..  trans-82.6-146.5172.667.40000109.7D13 A14 I37 F80 R81T11-D13 PolarHBondContact OG1-N 3.24Å; T11-D13 PolarHBondContact OG1-OD1 2.69Å; T11-A14 PolarHBondContact N-O 3.46Å; T11-A14 PolarHBondContact OG1-N 2.87Å; T11-A14 PolarHBondContact OG1-O 3.27Å; T11-I37 HydrophobicContact CG2-CG2 4.48Å; T11-F80 HydrophobicContact CG2-CB 4.18Å; T11-F80 HydrophobicContact CG2-CD1 4.4Å; T11-R81 PolarHBondContact O-NH1 2.87Å
12M96.1Very high94.2Very high40 Ų4058.8 Ų58.820%0.19731%0.313CS..SBendtrans-90.4-14.1164.5-64.8-55.3-44.200113.3R81 L101 L104 Q105 E108M12-R81 PolarHBondContact SD-NE 3.07Å; M12-R81 PolarHBondContact SD-NH2 2.83Å; M12-L101 HydrophobicContact CB-CD2 3.79Å; M12-L101 HydrophobicContact CG-CD2 4.05Å; M12-L104 HydrophobicContact CB-CB 3.53Å; M12-L104 HydrophobicContact CB-CD1 3.71Å; M12-L104 HydrophobicContact CB-CG 4.28Å; M12-L104 HydrophobicContact CE-CB 4.04Å; M12-L104 HydrophobicContact CG-CB 3.88Å; M12-Q105 HydrophobicContact CE-CB 4.45Å; M12-Q105 HydrophobicContact CG-CB 4.15Å; M12-Q105 HydrophobicContact SD-CB 3.73Å; M12-Q105 HydrophobicContact SD-CG 4.24Å; M12-E108 HydrophobicContact CE-CB 4.05Å; M12-E108 WeakPolarHBondContact CE-OE2 3.45Å
13D92.3Very high95.2Very high66 Ų6659.2 Ų59.235%0.35331%0.311SS..SBendtrans-143-6.3-162.363.5-29.6000114.8T11 K100 L101 L104T11-D13 PolarHBondContact OG1-N 3.24Å; T11-D13 PolarHBondContact OG1-OD1 2.69Å; D13-K100 VanDerWaalsContact OD2-CE 3.25Å; D13-K100 WeakPolarHBondContact OD2-CE 3.35Å; D13-K100 IonicContact OD2-NZ 3.16Å; D13-K100 PolarHBondContact OD2-NZ 2.8Å; D13-L101 WeakPolarHBondContact OD1-CD2 3.38Å; D13-L104 HydrophobicContact CB-CD1 3.86Å
14A94.6Very high95.7Very high41 Ų4151.4 Ų51.434%0.33928%0.279SS..  trans-148.5157.8-179.800000111.7T11T11-A14 PolarHBondContact N-O 3.46Å; T11-A14 PolarHBondContact OG1-N 2.87Å; T11-A14 PolarHBondContact OG1-O 3.27Å
15E96.6Very high95.9Very high104 Ų10449.9 Ų49.949%0.48627%0.268SS..EExtended strand (participates in β ladder)trans-114.7131.6163-54.8-142.2119.200109.1R8 T10R8-E15 WeakPolarHBondContact CD-OE2 3.45Å; R8-E15 IonicContact CZ-OE2 3.77Å; R8-E15 IonicContact NE-OE2 2.6Å; R8-E15 IonicContact NH1-OE2 3.59Å; R8-E15 PolarHBondContact NH1-OE2 3.17Å; T10-E15 HydrophobicContact CG2-CG 4.14Å; T10-E15 WeakPolarHBondContact CG2-OE1 3.49Å; T10-E15 PolarHBondContact OG1-OE1 2.74Å
16L96.3Very high96Very high28 Ų2847.8 Ų47.815%0.14726%0.257CS..EExtended strand (participates in β ladder)trans-112.9120.1177-54.7178.7000109R8 V9 F18 V33 T36 I37R8-L16 CarbonylContact C-O 3.57Å; R8-L16 WeakPolarHBondContact CA-O 3.16Å; V9-L16 HydrophobicContact CB-CB 4.44Å; V9-L16 PolarHBondContact N-O 3.23Å; V9-L16 PolarHBondContact O-N 3.08Å; L16-F18 HydrophobicContact CB-CD1 4.34Å; L16-F18 HydrophobicContact CB-CE1 4.07Å; L16-V33 HydrophobicContact CD1-CG1 4.2Å; L16-T36 HydrophobicContact CD1-CG2 3.88Å; L16-T36 HydrophobicContact CD2-CG2 3.8Å; L16-T36 HydrophobicContact CG-CG2 4.48Å; L16-I37 HydrophobicContact CD1-CG2 4.2Å
17E96.1Very high96.1Very high115 Ų11546.5 Ų46.554%0.53725%0.248SC..EExtended strand (participates in β ladder)trans-111131.3172.3-67.2-156.814900111.5V7 R8V7-E17 WeakPolarHBondContact O-CA 3.47Å; R8-E17 HydrophobicContact CB-CG 4.17Å; R8-E17 HydrophobicContact CG-CG 4.08Å; R8-E17 IonicContact CZ-OE1 3.64Å; R8-E17 IonicContact NE-OE1 2.79Å; R8-E17 PolarHBondContact NE-OE1 3.11Å; R8-E17 IonicContact NH2-OE1 3.63Å; R8-E17 PolarHBondContact NH2-OE1 3.38Å
18F94.4Very high96.1Very high53 Ų5351.5 Ų51.523%0.23227%0.271CS..EExtended strand (participates in β ladder)trans-158.9163174.750.1-87.8000112.1V7 V9 L16 I20 L29 Q32 V33V7-F18 PolarHBondContact N-O 2.96Å; V7-F18 PolarHBondContact O-N 2.83Å; V9-F18 HydrophobicContact CG2-CE1 4.27Å; V9-F18 HydrophobicContact CG2-CZ 4.2Å; L16-F18 HydrophobicContact CB-CD1 4.34Å; L16-F18 HydrophobicContact CB-CE1 4.07Å; F18-I20 HydrophobicContact CD2-CG2 3.96Å; F18-I20 HydrophobicContact CE2-CG2 3.89Å; F18-L29 HydrophobicContact CE2-CD1 3.41Å; F18-L29 VanDerWaalsContact CE2-CD1 3.41Å; F18-L29 HydrophobicContact CZ-CD1 3.48Å; F18-L29 VanDerWaalsContact CZ-CD1 3.48Å; F18-Q32 HydrophobicContact CD2-CG 4.44Å; F18-Q32 HydrophobicContact CE1-CG 4.5Å; F18-Q32 HydrophobicContact CE2-CB 4.48Å; F18-Q32 HydrophobicContact CE2-CG 3.96Å; F18-Q32 HydrophobicContact CZ-CB 4.47Å; F18-Q32 HydrophobicContact CZ-CG 4Å; F18-V33 HydrophobicContact CE1-CG2 4.33Å; F18-V33 HydrophobicContact CZ-CG2 4Å
19A95.4Very high96Very high62 Ų6248.1 Ų48.151%0.51226%0.258SS..EExtended strand (participates in β ladder)trans-93.8128177.100000111.2P4 I5P4-A19 HydrophobicContact CB-CB 4Å; I5-A19 WeakPolarHBondContact O-CA 3.17Å
20I95.7Very high96Very high10 Ų1048.4 Ų48.45%0.05126%0.26CS..EExtended strand (participates in β ladder)trans-103.8160.7170.172.3171.5000111.4I5 V7 F18 T24 L29 V65I5-I20 HydrophobicContact CB-CG1 3.92Å; I5-I20 HydrophobicContact CG2-CG1 4.39Å; I5-I20 PolarHBondContact N-O 3.3Å; I5-I20 PolarHBondContact O-N 2.72Å; V7-I20 HydrophobicContact CG2-CB 4.42Å; V7-I20 HydrophobicContact CG2-CD1 3.76Å; V7-I20 HydrophobicContact CG2-CG1 3.73Å; V7-I20 HydrophobicContact CG2-CG2 3.95Å; F18-I20 HydrophobicContact CD2-CG2 3.96Å; F18-I20 HydrophobicContact CE2-CG2 3.89Å; I20-T24 HydrophobicContact CB-CG2 4.08Å; I20-T24 HydrophobicContact CD1-CG2 4.36Å; I20-T24 HydrophobicContact CG2-CG2 4.29Å; I20-L29 HydrophobicContact CG2-CD1 4.2Å; I20-V65 HydrophobicContact CD1-CB 3.84Å; I20-V65 HydrophobicContact CD1-CG1 3.97Å; I20-V65 HydrophobicContact CD1-CG2 4.02Å
21Q95.1Very high96Very high94 Ų9449 Ų4944%0.43926%0.261SS..PPolyproline II helixtrans-86.9152.4173.9-66.6-65.2-21.300110.7N23 T24Q21-N23 WeakPolarHBondContact CB-OD1 3.44Å; Q21-N23 PolarHBondContact O-N 3.4Å; Q21-T24 PolarHBondContact N-OG1 2.73Å; Q21-T24 VanDerWaalsContact N-OG1 3.12Å; Q21-T24 VanDerWaalsContact O-CB 3.29Å; Q21-T24 WeakPolarHBondContact O-CB 3.41Å; Q21-T24 PolarHBondContact O-N 2.78Å; Q21-T24 PolarHBondContact O-OG1 3.17Å; Q21-T24 VanDerWaalsContact O-OG1 3.11Å
22P92.8Very high96Very high46 Ų4653.5 Ų53.530%0.29928%0.283SS..THydrogen-bonded Turntrans-60.3-14.9179.6-27.837000115.7P2 K3 I5 S66P2-P22 HydrophobicContact CB-CG 4.01Å; K3-P22 VanDerWaalsContact O-CG 3.29Å; K3-P22 WeakPolarHBondContact O-CG 3.27Å; I5-P22 HydrophobicContact CD1-CB 4.29Å; I5-P22 HydrophobicContact CD1-CG 4.29Å; I5-P22 HydrophobicContact CG1-CG 4.43Å; P22-S66 PolarHBondContact O-OG 2.76Å
23N94.3Very high96Very high98 Ų9851.6 Ų51.652%0.52427%0.273SS..THydrogen-bonded Turntrans-95.4-7.3174.965.6-24.9000114.5Q21 T25Q21-N23 WeakPolarHBondContact CB-OD1 3.44Å; Q21-N23 PolarHBondContact O-N 3.4Å; N23-T25 PolarHBondContact O-N 3.32Å
24T96.5Very high96.3Very high18 Ų1848.9 Ų48.911%0.1126%0.259CS..  trans-57.7131.1-176.5-64.10000111.9I20 Q21 Q28 L29 K64 V65I20-T24 HydrophobicContact CB-CG2 4.08Å; I20-T24 HydrophobicContact CD1-CG2 4.36Å; I20-T24 HydrophobicContact CG2-CG2 4.29Å; Q21-T24 PolarHBondContact N-OG1 2.73Å; Q21-T24 VanDerWaalsContact N-OG1 3.12Å; Q21-T24 VanDerWaalsContact O-CB 3.29Å; Q21-T24 WeakPolarHBondContact O-CB 3.41Å; Q21-T24 PolarHBondContact O-N 2.78Å; Q21-T24 PolarHBondContact O-OG1 3.17Å; Q21-T24 VanDerWaalsContact O-OG1 3.11Å; T24-Q28 HydrophobicContact CG2-CB 3.79Å; T24-L29 HydrophobicContact CG2-CB 4.46Å; T24-K64 CarbonylContact O-C 3.47Å; T24-K64 WeakPolarHBondContact O-CA 3.42Å; T24-V65 PolarHBondContact O-N 3.49Å
25T97.6Very high96.3Very high43 Ų4354.3 Ų54.326%0.26428%0.275SS..BIsolated β-bridgetrans-81.9161177.6680000112.3N23 K27 Q28 L29 K63N23-T25 PolarHBondContact O-N 3.32Å; T25-K27 PolarHBondContact O-N 2.85Å; T25-Q28 PolarHBondContact O-N 3.31Å; T25-Q28 WeakPolarHBondContact OG1-CG 3.46Å; T25-Q28 PolarHBondContact OG1-N 3.05Å; T25-Q28 VanDerWaalsContact OG1-N 3.1Å; T25-Q28 PolarHBondContact OG1-OE1 2.78Å; T25-L29 PolarHBondContact O-N 2.72Å; T25-K63 CarbonylContact C-O 3.58Å
26G96.8Very high96.3Very high0 Ų052.9 Ų52.90%027%0.273CS..Hα-helixtrans-60-34.8171.800000112.3F30 K63G26-F30 VanDerWaalsContact O-CB 3.22Å; G26-F30 WeakPolarHBondContact O-CB 3.14Å; G26-F30 PolarHBondContact O-N 3.48Å; G26-K63 PolarHBondContact N-O 3.04Å
27K97.6Very high96.2Very high50 Ų5053.1 Ų53.122%0.21727%0.274CS..Hα-helixtrans-61.7-49.8172.3-167.5175.6-170.4-77.40110.9T25 L29 F30 D31 L61 E495 P496T25-K27 PolarHBondContact O-N 2.85Å; K27-L29 VanDerWaalsContact C-N 3.34Å; K27-L29 PolarHBondContact O-N 3.25Å; K27-F30 PolarHBondContact O-N 2.57Å; K27-F30 VanDerWaalsContact O-N 3.16Å; K27-D31 WeakPolarHBondContact CG-OD1 2.97Å; K27-D31 WeakPolarHBondContact CG-OD2 3.07Å; K27-D31 IonicContact NZ-OD1 2.66Å; K27-D31 PolarHBondContact NZ-OD1 3.01Å; K27-D31 IonicContact NZ-OD2 2.86Å; K27-D31 PolarHBondContact NZ-OD2 2.88Å; K27-D31 VanDerWaalsContact O-CB 3.28Å; K27-D31 WeakPolarHBondContact O-CB 3.32Å; K27-D31 PolarHBondContact O-N 2.92Å; K27-L61 HydrophobicContact CB-CB 4.05Å; K27-L61 PolarHBondContact N-O 2.82Å; K27-E495 WeakPolarHBondContact CE-O 3.4Å; K27-E495 PolarHBondContact NZ-O 3.33Å; K27-P496 HydrophobicContact CD-CB 4.39Å
28Q97.5Very high96.2Very high105 Ų10549.8 Ų49.849%0.49127%0.271SS..Hα-helixtrans-60.5-40.9179.3-74.1169.9-3400113T24 T25 Q32T24-Q28 HydrophobicContact CG2-CB 3.79Å; T25-Q28 PolarHBondContact O-N 3.31Å; T25-Q28 WeakPolarHBondContact OG1-CG 3.46Å; T25-Q28 PolarHBondContact OG1-N 3.05Å; T25-Q28 VanDerWaalsContact OG1-N 3.1Å; T25-Q28 PolarHBondContact OG1-OE1 2.78Å; Q28-Q32 WeakPolarHBondContact O-CB 3.27Å; Q28-Q32 PolarHBondContact O-N 3.45Å; Q28-Q32 VanDerWaalsContact O-N 3.12Å
29L97.6Very high96.3Very high1 Ų147.5 Ų47.51%0.00526%0.261CS..Hα-helixtrans-65.7-41.3175174.457.9000111.8V7 V9 F18 I20 T24 T25 K27 V33 L47 L59 V65 F78V7-L29 HydrophobicContact CG1-CD1 4.06Å; V7-L29 HydrophobicContact CG1-CD2 4.38Å; V9-L29 HydrophobicContact CG2-CD1 4.4Å; F18-L29 HydrophobicContact CE2-CD1 3.41Å; F18-L29 VanDerWaalsContact CE2-CD1 3.41Å; F18-L29 HydrophobicContact CZ-CD1 3.48Å; F18-L29 VanDerWaalsContact CZ-CD1 3.48Å; I20-L29 HydrophobicContact CG2-CD1 4.2Å; T24-L29 HydrophobicContact CG2-CB 4.46Å; T25-L29 PolarHBondContact O-N 2.72Å; K27-L29 VanDerWaalsContact C-N 3.34Å; K27-L29 PolarHBondContact O-N 3.25Å; L29-V33 WeakPolarHBondContact O-CG2 3.44Å; L29-V33 PolarHBondContact O-N 3.01Å; L29-L47 HydrophobicContact CD2-CD1 4.09Å; L29-L47 HydrophobicContact CG-CD1 3.74Å; L29-L59 HydrophobicContact CD2-CD2 3.88Å; L29-L59 HydrophobicContact CG-CD2 4.45Å; L29-V65 HydrophobicContact CB-CG2 4.03Å; L29-V65 HydrophobicContact CD2-CG1 4.1Å; L29-V65 HydrophobicContact CD2-CG2 3.75Å; L29-F78 HydrophobicContact CD2-CD2 4.4Å; L29-F78 HydrophobicContact CD2-CE1 4.42Å; L29-F78 HydrophobicContact CD2-CE2 4.08Å; L29-F78 HydrophobicContact CD2-CZ 4.11Å
30F98.1Very high96.4Very high7 Ų748.8 Ų48.83%0.03125%0.253CS..Hα-helixtrans-69.1-47.9178.3179-84.9000112.3G26 K27 Q32 V33 V34 V42 F45 L47 L61 F80G26-F30 VanDerWaalsContact O-CB 3.22Å; G26-F30 WeakPolarHBondContact O-CB 3.14Å; G26-F30 PolarHBondContact O-N 3.48Å; K27-F30 PolarHBondContact O-N 2.57Å; K27-F30 VanDerWaalsContact O-N 3.16Å; F30-Q32 VanDerWaalsContact C-N 3.26Å; F30-Q32 PolarHBondContact O-N 2.86Å; F30-V33 WeakPolarHBondContact O-CB 3.38Å; F30-V33 PolarHBondContact O-N 2.99Å; F30-V33 VanDerWaalsContact O-N 3.07Å; F30-V34 HydrophobicContact CD1-CG1 4.15Å; F30-V34 HydrophobicContact CD1-CG2 4.41Å; F30-V34 HydrophobicContact CE1-CG1 3.66Å; F30-V34 HydrophobicContact CE1-CG2 4.22Å; F30-V34 HydrophobicContact CE2-CG1 4.26Å; F30-V34 HydrophobicContact CZ-CG1 3.73Å; F30-V34 PolarHBondContact O-N 2.8Å; F30-V42 HydrophobicContact CE1-CB 3.78Å; F30-V42 HydrophobicContact CE1-CG1 3.9Å; F30-V42 HydrophobicContact CZ-CB 3.98Å; F30-V42 HydrophobicContact CZ-CG1 4.36Å; F30-F45 HydrophobicContact CE2-CB 4.17Å; F30-F45 HydrophobicContact CZ-CB 4.28Å; F30-L47 HydrophobicContact CB-CD1 4.13Å; F30-L47 HydrophobicContact CD2-CD1 4.45Å; F30-L47 HydrophobicContact CD2-CG 4.28Å; F30-L61 HydrophobicContact CB-CD2 3.75Å; F30-L61 HydrophobicContact CD2-CD2 4.33Å; F30-L61 HydrophobicContact CG-CD2 4.03Å; F30-F80 HydrophobicContact CD2-CE2 4.2Å; F30-F80 HydrophobicContact CE2-CD2 4.47Å; F30-F80 AromaticContact CE2-CE2 3.67Å; F30-F80 HydrophobicContact CE2-CE2 3.67Å; F30-F80 HydrophobicContact CZ-CE2 4.21Å
31D97.6Very high96.4Very high46 Ų4648.3 Ų48.325%0.24625%0.25CS..Hα-helixtrans-56.5-40.5177.3-71-0.3000111K27 K35K27-D31 WeakPolarHBondContact CG-OD1 2.97Å; K27-D31 WeakPolarHBondContact CG-OD2 3.07Å; K27-D31 IonicContact NZ-OD1 2.66Å; K27-D31 PolarHBondContact NZ-OD1 3.01Å; K27-D31 IonicContact NZ-OD2 2.86Å; K27-D31 PolarHBondContact NZ-OD2 2.88Å; K27-D31 VanDerWaalsContact O-CB 3.28Å; K27-D31 WeakPolarHBondContact O-CB 3.32Å; K27-D31 PolarHBondContact O-N 2.92Å; D31-K35 VanDerWaalsContact O-CB 3.32Å; D31-K35 WeakPolarHBondContact O-CB 3.23Å; D31-K35 VanDerWaalsContact O-CG 3.29Å; D31-K35 WeakPolarHBondContact O-CG 3.4Å; D31-K35 PolarHBondContact O-N 2.95Å
32Q96.7Very high96.5Very high97 Ų9746.4 Ų46.445%0.45325%0.245SC..Hα-helixtrans-61.2-46.8174.7-177.5616000111.8F18 Q28 F30 T36F18-Q32 HydrophobicContact CD2-CG 4.44Å; F18-Q32 HydrophobicContact CE1-CG 4.5Å; F18-Q32 HydrophobicContact CE2-CB 4.48Å; F18-Q32 HydrophobicContact CE2-CG 3.96Å; F18-Q32 HydrophobicContact CZ-CB 4.47Å; F18-Q32 HydrophobicContact CZ-CG 4Å; Q28-Q32 WeakPolarHBondContact O-CB 3.27Å; Q28-Q32 PolarHBondContact O-N 3.45Å; Q28-Q32 VanDerWaalsContact O-N 3.12Å; F30-Q32 VanDerWaalsContact C-N 3.26Å; F30-Q32 PolarHBondContact O-N 2.86Å; Q32-T36 PolarHBondContact NE2-OG1 2.77Å; Q32-T36 WeakPolarHBondContact O-CB 3.5Å; Q32-T36 PolarHBondContact O-N 2.88Å; Q32-T36 PolarHBondContact O-OG1 3.13Å
33V97.4Very high96.6Very high0 Ų046.3 Ų46.30%024%0.238CC..Hα-helixtrans-62.2-51.3179.7171.20000110.9V9 L16 F18 L29 F30 K35 T36 I37 L47 F80V9-V33 HydrophobicContact CB-CG2 4.04Å; V9-V33 HydrophobicContact CG1-CG1 4.1Å; V9-V33 HydrophobicContact CG1-CG2 3.85Å; V9-V33 HydrophobicContact CG2-CG2 3.77Å; L16-V33 HydrophobicContact CD1-CG1 4.2Å; F18-V33 HydrophobicContact CE1-CG2 4.33Å; F18-V33 HydrophobicContact CZ-CG2 4Å; L29-V33 WeakPolarHBondContact O-CG2 3.44Å; L29-V33 PolarHBondContact O-N 3.01Å; F30-V33 WeakPolarHBondContact O-CB 3.38Å; F30-V33 PolarHBondContact O-N 2.99Å; F30-V33 VanDerWaalsContact O-N 3.07Å; V33-K35 PolarHBondContact O-N 3.05Å; V33-T36 PolarHBondContact O-N 3.44Å; V33-I37 WeakPolarHBondContact O-CG1 3.36Å; V33-I37 PolarHBondContact O-N 3.29Å; V33-L47 HydrophobicContact CG2-CD2 4.49Å; V33-F80 HydrophobicContact CG1-CB 4.41Å; V33-F80 HydrophobicContact CG1-CD2 3.66Å; V33-F80 HydrophobicContact CG1-CE2 4.05Å; V33-F80 HydrophobicContact CG1-CG 4.07Å
34V97.1Very high96.8Very high8 Ų841.8 Ų41.85%0.04821%0.214CC..Hα-helixtrans-67.9-34.9-175.2-58.40000112.3F30 I37 G38 L39 V42 F80F30-V34 HydrophobicContact CD1-CG1 4.15Å; F30-V34 HydrophobicContact CD1-CG2 4.41Å; F30-V34 HydrophobicContact CE1-CG1 3.66Å; F30-V34 HydrophobicContact CE1-CG2 4.22Å; F30-V34 HydrophobicContact CE2-CG1 4.26Å; F30-V34 HydrophobicContact CZ-CG1 3.73Å; F30-V34 PolarHBondContact O-N 2.8Å; V34-I37 PolarHBondContact O-N 2.74Å; V34-G38 PolarHBondContact O-N 3.12Å; V34-L39 HydrophobicContact CB-CB 4.43Å; V34-L39 HydrophobicContact CG1-CD2 4.34Å; V34-L39 PolarHBondContact O-N 2.81Å; V34-V42 HydrophobicContact CB-CG1 4.16Å; V34-V42 HydrophobicContact CG1-CG1 4.17Å; V34-V42 HydrophobicContact CG2-CG1 3.88Å; V34-F80 HydrophobicContact CG1-CE2 3.6Å; V34-F80 HydrophobicContact CG1-CZ 3.67Å
35K95.9Very high96.8Very high155 Ų15541.6 Ų41.667%0.67421%0.212SC*.Hα-helixtrans-64.9-42.7171.1-74.4-174.2176.4-162.50112.1D31 V33 I37 G38D31-K35 VanDerWaalsContact O-CB 3.32Å; D31-K35 WeakPolarHBondContact O-CB 3.23Å; D31-K35 VanDerWaalsContact O-CG 3.29Å; D31-K35 WeakPolarHBondContact O-CG 3.4Å; D31-K35 PolarHBondContact O-N 2.95Å; V33-K35 PolarHBondContact O-N 3.05Å; K35-I37 PolarHBondContact O-N 3.37Å; K35-G38 PolarHBondContact O-N 3.45Å
36T95.8Very high96.8Very high75 Ų7540 Ų4046%0.4620%0.203SC..Hα-helixtrans-63.2-25.4177.9-67.60000113.3L16 Q32 V33L16-T36 HydrophobicContact CD1-CG2 3.88Å; L16-T36 HydrophobicContact CD2-CG2 3.8Å; L16-T36 HydrophobicContact CG-CG2 4.48Å; Q32-T36 PolarHBondContact NE2-OG1 2.77Å; Q32-T36 WeakPolarHBondContact O-CB 3.5Å; Q32-T36 PolarHBondContact O-N 2.88Å; Q32-T36 PolarHBondContact O-OG1 3.13Å; V33-T36 PolarHBondContact O-N 3.44Å
37I95.6Very high96.9Very high32 Ų3240 Ų4016%0.16420%0.204CC..THydrogen-bonded Turntrans-1053.4176.868.8176.6000114.5T11 L16 V33 V34 K35 L39 F80 L101T11-I37 HydrophobicContact CG2-CG2 4.48Å; L16-I37 HydrophobicContact CD1-CG2 4.2Å; V33-I37 WeakPolarHBondContact O-CG1 3.36Å; V33-I37 PolarHBondContact O-N 3.29Å; V34-I37 PolarHBondContact O-N 2.74Å; K35-I37 PolarHBondContact O-N 3.37Å; I37-L39 VanDerWaalsContact C-N 3.35Å; I37-L39 HydrophobicContact CD1-CB 3.97Å; I37-L39 HydrophobicContact CD1-CD1 4.25Å; I37-L39 HydrophobicContact CG1-CB 3.81Å; I37-L39 PolarHBondContact O-N 3.38Å; I37-F80 HydrophobicContact CD1-CD1 4.35Å; I37-F80 HydrophobicContact CD1-CE1 3.87Å; I37-F80 HydrophobicContact CD1-CZ 4.25Å; I37-L101 HydrophobicContact CD1-CD1 4.02Å
38G95.2Very high96.8Very high45 Ų4540.5 Ų40.546%0.46421%0.207SC..THydrogen-bonded Turntrans70.620179.500000115.9V34 K35 Q95V34-G38 PolarHBondContact O-N 3.12Å; K35-G38 PolarHBondContact O-N 3.45Å; G38-Q95 PolarHBondContact O-NE2 2.86Å
39L96.8Very high96.8Very high6 Ų636.3 Ų36.33%0.03119%0.186CC..  trans-92.7124.9-174.4-171.3148.3000112.1V34 I37 V42 F45 F80 I97 L101V34-L39 HydrophobicContact CB-CB 4.43Å; V34-L39 HydrophobicContact CG1-CD2 4.34Å; V34-L39 PolarHBondContact O-N 2.81Å; I37-L39 VanDerWaalsContact C-N 3.35Å; I37-L39 HydrophobicContact CD1-CB 3.97Å; I37-L39 HydrophobicContact CD1-CD1 4.25Å; I37-L39 HydrophobicContact CG1-CB 3.81Å; I37-L39 PolarHBondContact O-N 3.38Å; L39-V42 HydrophobicContact CD2-CG1 4.2Å; L39-F45 HydrophobicContact CD1-CD2 4.07Å; L39-F45 HydrophobicContact CD1-CE2 3.6Å; L39-F45 HydrophobicContact CD1-CZ 3.87Å; L39-F45 HydrophobicContact CD2-CD2 3.82Å; L39-F45 HydrophobicContact CD2-CE2 3.99Å; L39-F45 HydrophobicContact CG-CE2 4.37Å; L39-F80 HydrophobicContact CD1-CE1 4.41Å; L39-I97 HydrophobicContact CB-CG2 4.22Å; L39-I97 HydrophobicContact CD1-CG1 4.5Å; L39-I97 HydrophobicContact CD1-CG2 4.5Å; L39-I97 HydrophobicContact CG-CG2 4.49Å; L39-L101 HydrophobicContact CD1-CD1 3.82Å
40R96.1Very high96.6Very high89 Ų8939.4 Ų39.434%0.33621%0.205SC..  trans-106.5-23.4178.6-62.2178.563177.72.3113.3V42 E301 M305R40-V42 PolarHBondContact O-N 3.39Å; R40-E301 IonicContact CZ-OE1 3.4Å; R40-E301 IonicContact NE-OE1 2.61Å; R40-E301 IonicContact NH2-OE1 3.39Å; R40-E301 PolarHBondContact NH2-OE1 3.03Å; R40-M305 HydrophobicContact CB-CE 3.61Å; R40-M305 HydrophobicContact CB-SD 3.97Å; R40-M305 VanDerWaalsContact CZ-CG 3.48Å
41E96.7Very high96.3Very high0 Ų039.4 Ų39.40%021%0.205CC..  trans-76.146.3177.7-61.4171.7-95.800112.9W43 Y44 F45 I94 Q95 T98 M305E41-W43 HydrophobicContact CB-CH2 4.16Å; E41-W43 HydrophobicContact CB-CZ2 3.92Å; E41-W43 HydrophobicContact CG-CH2 3.93Å; E41-W43 HydrophobicContact CG-CZ2 3.81Å; E41-W43 PolarHBondContact O-N 2.67Å; E41-Y44 HydrophobicContact CB-CD2 4.15Å; E41-Y44 HydrophobicContact CB-CE2 4.27Å; E41-Y44 PolarHBondContact O-N 3.47Å; E41-F45 WeakPolarHBondContact O-CD2 3.44Å; E41-I94 HydrophobicContact CG-CB 4.45Å; E41-I94 HydrophobicContact CG-CD1 4.49Å; E41-I94 PolarHBondContact OE1-N 2.85Å; E41-I94 PolarHBondContact OE2-N 3.04Å; E41-Q95 WeakPolarHBondContact OE1-CB 3.42Å; E41-Q95 WeakPolarHBondContact OE1-CG 3.22Å; E41-Q95 PolarHBondContact OE1-N 2.8Å; E41-T98 HydrophobicContact CB-CG2 4.03Å; E41-T98 HydrophobicContact CG-CG2 4.49Å; E41-T98 WeakPolarHBondContact OE1-CB 3.22Å; E41-T98 WeakPolarHBondContact OE1-CG2 3.41Å; E41-T98 PolarHBondContact OE1-OG1 2.93Å; E41-M305 HydrophobicContact CG-CE 3.54Å
42V96.5Very high95.9Very high53 Ų5341 Ų4132%0.32121%0.214SC..G310 helixtrans-57.2-25.3-169.7-66.40000114.2F30 V34 L39 R40 Y44 F45F30-V42 HydrophobicContact CE1-CB 3.78Å; F30-V42 HydrophobicContact CE1-CG1 3.9Å; F30-V42 HydrophobicContact CZ-CB 3.98Å; F30-V42 HydrophobicContact CZ-CG1 4.36Å; V34-V42 HydrophobicContact CB-CG1 4.16Å; V34-V42 HydrophobicContact CG1-CG1 4.17Å; V34-V42 HydrophobicContact CG2-CG1 3.88Å; L39-V42 HydrophobicContact CD2-CG1 4.2Å; R40-V42 PolarHBondContact O-N 3.39Å; V42-Y44 PolarHBondContact O-N 2.63Å; V42-F45 PolarHBondContact O-N 3.25Å
43W95.4Very high95.5Very high44 Ų4442.4 Ų42.417%0.16722%0.219CC..G310 helixtrans-66.9-18.3-172.954.678.9000114.3E41 F84 L290 R293 V302 M305E41-W43 HydrophobicContact CB-CH2 4.16Å; E41-W43 HydrophobicContact CB-CZ2 3.92Å; E41-W43 HydrophobicContact CG-CH2 3.93Å; E41-W43 HydrophobicContact CG-CZ2 3.81Å; E41-W43 PolarHBondContact O-N 2.67Å; W43-F84 WeakPolarHBondContact O-CD2 3.4Å; W43-L290 HydrophobicContact CB-CD2 4.09Å; W43-L290 HydrophobicContact CG-CD2 4.03Å; W43-R293 VanDerWaalsContact CE3-NH1 3.34Å; W43-V302 HydrophobicContact CH2-CG2 4.19Å; W43-M305 HydrophobicContact CH2-CE 4.13Å; W43-M305 HydrophobicContact CH2-SD 4.4Å
44Y97.7Very high95Very high4 Ų445 Ų452%0.01625%0.245CC..G310 helixtrans-80-25.1172.1-62.5-58.9000113.7E41 V42 K83 F84 P86 E92 L93 T98 F102E41-Y44 HydrophobicContact CB-CD2 4.15Å; E41-Y44 HydrophobicContact CB-CE2 4.27Å; E41-Y44 PolarHBondContact O-N 3.47Å; V42-Y44 PolarHBondContact O-N 2.63Å; Y44-K83 PolarHBondContact O-N 3.32Å; Y44-F84 PolarHBondContact O-N 2.69Å; Y44-P86 HydrophobicContact CE1-CB 4.42Å; Y44-E92 WeakPolarHBondContact OH-CB 3.3Å; Y44-E92 PolarHBondContact OH-O 3.32Å; Y44-E92 PolarHBondContact OH-OE2 2.96Å; Y44-E92 VanDerWaalsContact OH-OE2 3.09Å; Y44-L93 HydrophobicContact CD2-CD2 4.49Å; Y44-L93 HydrophobicContact CE2-CD2 3.95Å; Y44-T98 HydrophobicContact CD2-CG2 4.22Å; Y44-F102 HydrophobicContact CD1-CE2 4.34Å; Y44-F102 AromaticContact CD1-CZ 3.97Å; Y44-F102 HydrophobicContact CD1-CZ 3.97Å; Y44-F102 AromaticContact CD2-CE2 3.75Å; Y44-F102 HydrophobicContact CD2-CE2 3.75Å; Y44-F102 HydrophobicContact CD2-CZ 4.22Å; Y44-F102 HydrophobicContact CE2-CE2 4.43Å; Y44-F102 AromaticContact CG-CE2 3.7Å; Y44-F102 HydrophobicContact CG-CE2 3.7Å; Y44-F102 AromaticContact CG-CZ 3.7Å; Y44-F102 HydrophobicContact CG-CZ 3.7Å
45F98.1Very high94.5Very high14 Ų1448.3 Ų48.36%0.06126%0.259CS..EExtended strand (participates in β ladder)trans-103.2165.6-160.4-64.6-87.1000114.3F30 L39 E41 V42 F80 R81 A82 T98 L101 F102F30-F45 HydrophobicContact CE2-CB 4.17Å; F30-F45 HydrophobicContact CZ-CB 4.28Å; L39-F45 HydrophobicContact CD1-CD2 4.07Å; L39-F45 HydrophobicContact CD1-CE2 3.6Å; L39-F45 HydrophobicContact CD1-CZ 3.87Å; L39-F45 HydrophobicContact CD2-CD2 3.82Å; L39-F45 HydrophobicContact CD2-CE2 3.99Å; L39-F45 HydrophobicContact CG-CE2 4.37Å; E41-F45 WeakPolarHBondContact O-CD2 3.44Å; V42-F45 PolarHBondContact O-N 3.25Å; F45-F80 HydrophobicContact CB-CE1 3.96Å; F45-F80 HydrophobicContact CB-CE2 3.8Å; F45-F80 HydrophobicContact CB-CZ 3.39Å; F45-F80 HydrophobicContact CD1-CD1 4.01Å; F45-F80 AromaticContact CD1-CE1 3.32Å; F45-F80 HydrophobicContact CD1-CE1 3.32Å; F45-F80 AromaticContact CD1-CZ 3.71Å; F45-F80 HydrophobicContact CD1-CZ 3.71Å; F45-F80 HydrophobicContact CD2-CE1 4.42Å; F45-F80 HydrophobicContact CD2-CZ 4.21Å; F45-F80 AromaticContact CE1-CE1 3.92Å; F45-F80 HydrophobicContact CE1-CE1 3.92Å; F45-F80 AromaticContact CG-CE1 3.64Å; F45-F80 HydrophobicContact CG-CE1 3.64Å; F45-F80 HydrophobicContact CG-CE2 4.37Å; F45-F80 AromaticContact CG-CZ 3.49Å; F45-F80 HydrophobicContact CG-CZ 3.49Å; F45-F80 VanDerWaalsContact CG-CZ 3.49Å; F45-R81 WeakPolarHBondContact CA-O 3.22Å; F45-A82 HydrophobicContact CD1-CB 4.27Å; F45-A82 HydrophobicContact CE1-CB 4.08Å; F45-T98 HydrophobicContact CE2-CG2 3.93Å; F45-T98 HydrophobicContact CZ-CG2 4.09Å; F45-L101 HydrophobicContact CE1-CB 4.01Å; F45-L101 HydrophobicContact CE1-CD1 4.07Å; F45-L101 HydrophobicContact CZ-CB 4.21Å; F45-L101 HydrophobicContact CZ-CD1 4.34Å; F45-F102 HydrophobicContact CE2-CE2 4.38Å; F45-F102 HydrophobicContact CZ-CD2 4.17Å; F45-F102 HydrophobicContact CZ-CE2 4.04Å
46G97.4Very high94.3Very high8 Ų844.2 Ų44.28%0.08225%0.249CC..EExtended strand (participates in β ladder)trans-157.7170.2169.100000111.8R81G46-R81 PolarHBondContact N-O 3.14Å; G46-R81 PolarHBondContact O-N 3.49Å; G46-R81 VanDerWaalsContact O-N 3.11Å
47L97.9Very high94.1Very high2 Ų242.1 Ų42.11%0.0124%0.236CC..EExtended strand (participates in β ladder)trans-99.3117.2169.2-69.7167.6000109V9 L29 F30 V33 L59 F78 F80V9-L47 HydrophobicContact CG1-CD2 3.45Å; V9-L47 VanDerWaalsContact CG1-CD2 3.45Å; V9-L47 HydrophobicContact CG2-CD2 4.37Å; L29-L47 HydrophobicContact CD2-CD1 4.09Å; L29-L47 HydrophobicContact CG-CD1 3.74Å; F30-L47 HydrophobicContact CB-CD1 4.13Å; F30-L47 HydrophobicContact CD2-CD1 4.45Å; F30-L47 HydrophobicContact CD2-CG 4.28Å; V33-L47 HydrophobicContact CG2-CD2 4.49Å; L47-L59 HydrophobicContact CB-CB 3.96Å; L47-L59 HydrophobicContact CB-CD2 4.03Å; L47-L59 HydrophobicContact CD1-CD2 3.73Å; L47-L59 WeakPolarHBondContact O-CB 3.41Å; L47-L59 PolarHBondContact O-N 3Å; L47-F78 HydrophobicContact CB-CD1 4.18Å; L47-F78 HydrophobicContact CD2-CB 4.18Å; L47-F80 HydrophobicContact CD2-CB 4.08Å; L47-F80 HydrophobicContact CD2-CD2 3.96Å; L47-F80 HydrophobicContact CG-CD2 4.46Å
48Q96.9Very high94Very high59 Ų5942.8 Ų42.828%0.27624%0.236SC..EExtended strand (participates in β ladder)trans-95.7139.8174-170.6-172.877.700109.8T57 W58 F78 K79Q48-T57 CarbonylContact C-O 3.59Å; Q48-T57 VanDerWaalsContact CA-O 3.28Å; Q48-T57 WeakPolarHBondContact CA-O 3.49Å; Q48-W58 HydrophobicContact CB-CD2 4.47Å; Q48-W58 HydrophobicContact CB-CE3 3.97Å; Q48-W58 HydrophobicContact CB-CH2 4.39Å; Q48-W58 HydrophobicContact CB-CZ3 3.92Å; Q48-F78 CarbonylContact O-C 3.49Å; Q48-F78 VanDerWaalsContact O-CA 3.27Å; Q48-F78 WeakPolarHBondContact O-CA 3.38Å; Q48-K79 PolarHBondContact N-O 2.84Å; Q48-K79 PolarHBondContact O-N 3.02Å
49Y96Very high94.1Very high17 Ų1741.3 Ų41.37%0.06722%0.217CC..EExtended strand (participates in β ladder)trans-138.9165.1174.765.5-81.1000111D51 P56 T57 L59 Q68 V70 F78Y49-D51 HydrophobicContact CE2-CB 4.09Å; Y49-P56 CarbonylContact O-C 3.56Å; Y49-P56 WeakPolarHBondContact O-CA 3.49Å; Y49-T57 WeakPolarHBondContact CD1-O 3.4Å; Y49-T57 HydrophobicContact CE1-CG2 3.87Å; Y49-T57 HydrophobicContact CE2-CG2 4.27Å; Y49-T57 PolarHBondContact N-O 2.98Å; Y49-T57 PolarHBondContact O-N 2.6Å; Y49-T57 VanDerWaalsContact OH-CG2 3.26Å; Y49-T57 WeakPolarHBondContact OH-CG2 3.28Å; Y49-L59 HydrophobicContact CD1-CB 4.29Å; Y49-L59 HydrophobicContact CE1-CB 4.25Å; Y49-L59 HydrophobicContact CE1-CD1 4.39Å; Y49-Q68 PolarHBondContact OH-O 3.11Å; Y49-V70 HydrophobicContact CD2-CB 4.02Å; Y49-V70 HydrophobicContact CD2-CG1 3.91Å; Y49-V70 HydrophobicContact CD2-CG2 3.81Å; Y49-V70 HydrophobicContact CE2-CB 4.28Å; Y49-V70 HydrophobicContact CE2-CG2 3.84Å; Y49-V70 HydrophobicContact CG-CG1 4.33Å; Y49-V70 HydrophobicContact CG-CG2 4.28Å; Y49-F78 HydrophobicContact CD1-CD1 4.27Å; Y49-F78 AromaticContact CD1-CE1 3.96Å; Y49-F78 HydrophobicContact CD1-CE1 3.96Å; Y49-F78 HydrophobicContact CG-CD1 4.32Å; Y49-F78 AromaticContact CG-CE1 4Å; Y49-F78 HydrophobicContact CG-CE1 4Å
50V93.9Very high94Very high66 Ų6645.6 Ų45.640%0.424%0.236SC..EExtended strand (participates in β ladder)trans-94.4128.2168.8-176.50000108.6R71V50-R71 VanDerWaalsContact O-CB 3.26Å; V50-R71 WeakPolarHBondContact O-CB 3.27Å; V50-R71 PolarHBondContact O-N 2.82Å
51D90.8Very high93.9Very high7 Ų744 Ų444%0.03723%0.234CC..BIsolated β-bridgetrans-79171.3177.876.5-3.3000112.6Y49 K53 G54 F55 E69 R275Y49-D51 HydrophobicContact CE2-CB 4.09Å; D51-K53 PolarHBondContact O-N 2.84Å; D51-K53 VanDerWaalsContact OD1-CA 3.28Å; D51-K53 WeakPolarHBondContact OD1-CA 3.47Å; D51-K53 WeakPolarHBondContact OD1-CB 3.49Å; D51-K53 PolarHBondContact OD1-N 2.77Å; D51-G54 PolarHBondContact O-N 3.42Å; D51-G54 PolarHBondContact OD1-N 2.92Å; D51-F55 PolarHBondContact N-O 2.88Å; D51-F55 PolarHBondContact OD1-N 2.92Å; D51-E69 CarbonylContact C-O 3.49Å; D51-E69 VanDerWaalsContact CA-O 3.3Å; D51-E69 WeakPolarHBondContact CA-O 3.03Å; D51-E69 WeakPolarHBondContact CB-O 3.41Å; D51-R275 IonicContact OD2-CZ 3.73Å; D51-R275 IonicContact OD2-NH1 2.65Å; D51-R275 PolarHBondContact OD2-NH1 3.44Å; D51-R275 IonicContact OD2-NH2 2.98Å; D51-R275 PolarHBondContact OD2-NH2 2.8Å
52N90.4Very high93.7Very high81 Ų8147.1 Ų47.143%0.43325%0.251SS..THydrogen-bonded Turntrans-61.3-2.7174.7-72.3-72.2000114.2E69 V70 K72N52-E69 PolarHBondContact N-O 3.18Å; N52-E69 PolarHBondContact ND2-O 3.34Å; N52-V70 PolarHBondContact ND2-O 3.39Å; N52-K72 PolarHBondContact OD1-N 3.04Å
53K88Confident93.7Very high125 Ų12549 Ų4954%0.54326%0.255SS..THydrogen-bonded Turntrans-110.67.6177-55.6-174.8-179.787.10112.2D51 F55 E69D51-K53 PolarHBondContact O-N 2.84Å; D51-K53 VanDerWaalsContact OD1-CA 3.28Å; D51-K53 WeakPolarHBondContact OD1-CA 3.47Å; D51-K53 WeakPolarHBondContact OD1-CB 3.49Å; D51-K53 PolarHBondContact OD1-N 2.77Å; K53-F55 HydrophobicContact CB-CD2 3.78Å; K53-F55 HydrophobicContact CB-CE2 4.03Å; K53-F55 WeakPolarHBondContact O-CD2 3.45Å; K53-F55 VanDerWaalsContact O-CE2 3.31Å; K53-F55 WeakPolarHBondContact O-CE2 3.46Å; K53-E69 IonicContact NZ-OE1 3.5Å; K53-E69 IonicContact NZ-OE2 3.07Å; K53-E69 PolarHBondContact NZ-OE2 2.75Å
54G88Confident93.7Very high54 Ų5452.2 Ų52.256%0.55727%0.27SS*.SBendtrans82.410.4175.800000115.5D51D51-G54 PolarHBondContact O-N 3.42Å; D51-G54 PolarHBondContact OD1-N 2.92Å
55F86.3Confident93.6Very high78 Ų7852.1 Ų52.134%0.34227%0.269SS..  trans-102.9139.6-174.9-66-84.9000113D51 K53 T57D51-F55 PolarHBondContact N-O 2.88Å; D51-F55 PolarHBondContact OD1-N 2.92Å; K53-F55 HydrophobicContact CB-CD2 3.78Å; K53-F55 HydrophobicContact CB-CE2 4.03Å; K53-F55 WeakPolarHBondContact O-CD2 3.45Å; K53-F55 VanDerWaalsContact O-CE2 3.31Å; K53-F55 WeakPolarHBondContact O-CE2 3.46Å; F55-T57 PolarHBondContact O-OG1 3.02Å
56P90.5Very high93.3Very high70 Ų7054.7 Ų54.746%0.45529%0.289SS..EExtended strand (participates in β ladder)trans-66.1134.317228.2-34.2000111.1Y49Y49-P56 CarbonylContact O-C 3.56Å; Y49-P56 WeakPolarHBondContact O-CA 3.49Å
57T91.5Very high93.1Very high30 Ų3057.7 Ų57.718%0.18431%0.313CS..EExtended strand (participates in β ladder)trans-145143-170.1-480000110.3Q48 Y49 F55 R275Q48-T57 CarbonylContact C-O 3.59Å; Q48-T57 VanDerWaalsContact CA-O 3.28Å; Q48-T57 WeakPolarHBondContact CA-O 3.49Å; Y49-T57 WeakPolarHBondContact CD1-O 3.4Å; Y49-T57 HydrophobicContact CE1-CG2 3.87Å; Y49-T57 HydrophobicContact CE2-CG2 4.27Å; Y49-T57 PolarHBondContact N-O 2.98Å; Y49-T57 PolarHBondContact O-N 2.6Å; Y49-T57 VanDerWaalsContact OH-CG2 3.26Å; Y49-T57 WeakPolarHBondContact OH-CG2 3.28Å; F55-T57 PolarHBondContact O-OG1 3.02Å; T57-R275 PolarHBondContact OG1-NH2 3.45Å
58W94.9Very high92.9Very high46 Ų4658.3 Ų58.317%0.17432%0.316CS..EExtended strand (participates in β ladder)trans-89.3134.6172-65.2104.4000110.6Q48 R81 K83Q48-W58 HydrophobicContact CB-CD2 4.47Å; Q48-W58 HydrophobicContact CB-CE3 3.97Å; Q48-W58 HydrophobicContact CB-CH2 4.39Å; Q48-W58 HydrophobicContact CB-CZ3 3.92Å; W58-R81 HydrophobicContact CH2-CB 3.89Å; W58-R81 HydrophobicContact CZ3-CB 4.25Å; W58-K83 HydrophobicContact CD2-CB 4.41Å; W58-K83 HydrophobicContact CD2-CD 4Å; W58-K83 HydrophobicContact CD2-CG 4.08Å; W58-K83 HydrophobicContact CE3-CB 4.33Å; W58-K83 HydrophobicContact CE3-CD 4.35Å; W58-K83 HydrophobicContact CE3-CG 4.46Å; W58-K83 HydrophobicContact CG-CD 4.2Å; W58-K83 HydrophobicContact CH2-CB 3.65Å; W58-K83 HydrophobicContact CH2-CG 4.22Å; W58-K83 HydrophobicContact CZ2-CB 3.74Å; W58-K83 HydrophobicContact CZ2-CG 3.83Å; W58-K83 HydrophobicContact CZ3-CB 3.96Å
59L95.8Very high92.6Very high14 Ų1460.6 Ų60.67%0.07333%0.326CS..PPolyproline II helixtrans-65.2133.2174.1-173.571.1000110.1L29 L47 Y49 V65 F78L29-L59 HydrophobicContact CD2-CD2 3.88Å; L29-L59 HydrophobicContact CG-CD2 4.45Å; L47-L59 HydrophobicContact CB-CB 3.96Å; L47-L59 HydrophobicContact CB-CD2 4.03Å; L47-L59 HydrophobicContact CD1-CD2 3.73Å; L47-L59 WeakPolarHBondContact O-CB 3.41Å; L47-L59 PolarHBondContact O-N 3Å; Y49-L59 HydrophobicContact CD1-CB 4.29Å; Y49-L59 HydrophobicContact CE1-CB 4.25Å; Y49-L59 HydrophobicContact CE1-CD1 4.39Å; L59-V65 HydrophobicContact CD1-CG1 4.39Å; L59-V65 HydrophobicContact CD1-CG2 4.44Å; L59-V65 HydrophobicContact CD2-CG2 4.48Å; L59-F78 HydrophobicContact CD1-CE1 4.09Å; L59-F78 HydrophobicContact CD2-CE1 4.34Å
60K94.3Very high92.4Very high97 Ų9760.4 Ų60.442%0.42233%0.327SS..PPolyproline II helixtrans-89.8127.1175.2-54.5-173.9176.2-169.90109.8D62 K63 Q68K60-D62 VanDerWaalsContact C-N 3.33Å; K60-D62 WeakPolarHBondContact CB-OD1 3.4Å; K60-D62 PolarHBondContact O-N 2.59Å; K60-K63 HydrophobicContact CB-CG 4.42Å; K60-K63 HydrophobicContact CD-CD 4.42Å; K60-K63 PolarHBondContact O-N 2.85Å; K60-Q68 VanDerWaalsContact CB-OE1 3.29Å; K60-Q68 PolarHBondContact O-NE2 3.16Å
61L94.5Very high92.3Very high55 Ų5563.7 Ų63.729%0.28833%0.332SS..THydrogen-bonded Turntrans-70.6-31.6-174.4-54.8-175000112.1K27 F30 K63K27-L61 HydrophobicContact CB-CB 4.05Å; K27-L61 PolarHBondContact N-O 2.82Å; F30-L61 HydrophobicContact CB-CD2 3.75Å; F30-L61 HydrophobicContact CD2-CD2 4.33Å; F30-L61 HydrophobicContact CG-CD2 4.03Å; L61-K63 VanDerWaalsContact C-N 3.26Å; L61-K63 PolarHBondContact O-N 3.44Å
62D93.6Very high92.2Very high66 Ų6672.2 Ų72.235%0.35337%0.369SS..THydrogen-bonded Turntrans-74.5-3.6-179.372-59.3000114.8K60K60-D62 VanDerWaalsContact C-N 3.33Å; K60-D62 WeakPolarHBondContact CB-OD1 3.4Å; K60-D62 PolarHBondContact O-N 2.59Å
63K95.1Very high92.3Very high93 Ų9371.6 Ų71.640%0.40436%0.364SS..SBendtrans-126.4149.9-174.1-53.3-158.3-172.4-500112.9T25 G26 K60 L61 V65 Q68T25-K63 CarbonylContact C-O 3.58Å; G26-K63 PolarHBondContact N-O 3.04Å; K60-K63 HydrophobicContact CB-CG 4.42Å; K60-K63 HydrophobicContact CD-CD 4.42Å; K60-K63 PolarHBondContact O-N 2.85Å; L61-K63 VanDerWaalsContact C-N 3.26Å; L61-K63 PolarHBondContact O-N 3.44Å; K63-V65 PolarHBondContact O-N 3.01Å; K63-Q68 HydrophobicContact CB-CG 4.12Å; K63-Q68 PolarHBondContact O-NE2 3.01Å; K63-Q68 VanDerWaalsContact O-NE2 3.11Å
64K96.2Very high92.5Very high111 Ų11171.5 Ų71.548%0.48337%0.369SS..BIsolated β-bridgetrans-56.3135172.6-63.1-178.6175174.30110.4T24 S66 A67 Q68T24-K64 CarbonylContact O-C 3.47Å; T24-K64 WeakPolarHBondContact O-CA 3.42Å; K64-S66 VanDerWaalsContact C-N 3.26Å; K64-S66 PolarHBondContact O-N 3.28Å; K64-A67 HydrophobicContact CB-CB 4.08Å; K64-A67 PolarHBondContact O-N 2.87Å; K64-Q68 WeakPolarHBondContact O-CG 3.23Å
65V94.9Very high92.8Very high2 Ų270 Ų701%0.01235%0.35CS..G310 helixtrans-58.8-42.4-179.2-178.70000110.7I20 T24 L29 L59 K63 A67 Q68 F78I20-V65 HydrophobicContact CD1-CB 3.84Å; I20-V65 HydrophobicContact CD1-CG1 3.97Å; I20-V65 HydrophobicContact CD1-CG2 4.02Å; T24-V65 PolarHBondContact O-N 3.49Å; L29-V65 HydrophobicContact CB-CG2 4.03Å; L29-V65 HydrophobicContact CD2-CG1 4.1Å; L29-V65 HydrophobicContact CD2-CG2 3.75Å; L59-V65 HydrophobicContact CD1-CG1 4.39Å; L59-V65 HydrophobicContact CD1-CG2 4.44Å; L59-V65 HydrophobicContact CD2-CG2 4.48Å; K63-V65 PolarHBondContact O-N 3.01Å; V65-A67 PolarHBondContact O-N 3.05Å; V65-A67 VanDerWaalsContact O-N 3.12Å; V65-Q68 PolarHBondContact O-N 3.34Å; V65-F78 HydrophobicContact CG1-CE1 4.47Å; V65-F78 HydrophobicContact CG1-CE2 4.36Å; V65-F78 HydrophobicContact CG1-CZ 3.65Å
66S92.5Very high93.3Very high68 Ų6867.2 Ų67.248%0.47634%0.338SS..G310 helixtrans-58.8-18.817553.20000115.1P22 K64P22-S66 PolarHBondContact O-OG 2.76Å; K64-S66 VanDerWaalsContact C-N 3.26Å; K64-S66 PolarHBondContact O-N 3.28Å
67A93.8Very high93.6Very high71 Ų7167 Ų6759%0.58733%0.331SS*.G310 helixtrans-102.111.8-175.900000114K64 V65K64-A67 HydrophobicContact CB-CB 4.08Å; K64-A67 PolarHBondContact O-N 2.87Å; V65-A67 PolarHBondContact O-N 3.05Å; V65-A67 VanDerWaalsContact O-N 3.12Å
68Q92.8Very high93.9Very high15 Ų1565.8 Ų65.87%0.0732%0.323CS..SBendtrans-113.423.1-172.2-65.3-170.462.800114.7Y49 K60 K63 K64 V65 V70Y49-Q68 PolarHBondContact OH-O 3.11Å; K60-Q68 VanDerWaalsContact CB-OE1 3.29Å; K60-Q68 PolarHBondContact O-NE2 3.16Å; K63-Q68 HydrophobicContact CB-CG 4.12Å; K63-Q68 PolarHBondContact O-NE2 3.01Å; K63-Q68 VanDerWaalsContact O-NE2 3.11Å; K64-Q68 WeakPolarHBondContact O-CG 3.23Å; V65-Q68 PolarHBondContact O-N 3.34Å; Q68-V70 HydrophobicContact CB-CG2 4.5Å; Q68-V70 PolarHBondContact O-N 2.73Å; Q68-V70 VanDerWaalsContact O-N 3.09Å
69E91.1Very high94.1Very high106 Ų10668.1 Ų68.150%0.49533%0.334SS..  trans53.229.2178.6-60.3-172.3-14700115D51 N52 K53D51-E69 CarbonylContact C-O 3.49Å; D51-E69 VanDerWaalsContact CA-O 3.3Å; D51-E69 WeakPolarHBondContact CA-O 3.03Å; D51-E69 WeakPolarHBondContact CB-O 3.41Å; N52-E69 PolarHBondContact N-O 3.18Å; N52-E69 PolarHBondContact ND2-O 3.34Å; K53-E69 IonicContact NZ-OE1 3.5Å; K53-E69 IonicContact NZ-OE2 3.07Å; K53-E69 PolarHBondContact NZ-OE2 2.75Å
70V92.1Very high94.2Very high13 Ų1367.5 Ų67.58%0.07933%0.331CS..BIsolated β-bridgetrans-56.3138171.8-170.30000110Y49 N52 Q68 K72 L76 F78Y49-V70 HydrophobicContact CD2-CB 4.02Å; Y49-V70 HydrophobicContact CD2-CG1 3.91Å; Y49-V70 HydrophobicContact CD2-CG2 3.81Å; Y49-V70 HydrophobicContact CE2-CB 4.28Å; Y49-V70 HydrophobicContact CE2-CG2 3.84Å; Y49-V70 HydrophobicContact CG-CG1 4.33Å; Y49-V70 HydrophobicContact CG-CG2 4.28Å; N52-V70 PolarHBondContact ND2-O 3.39Å; Q68-V70 HydrophobicContact CB-CG2 4.5Å; Q68-V70 PolarHBondContact O-N 2.73Å; Q68-V70 VanDerWaalsContact O-N 3.09Å; V70-K72 PolarHBondContact O-N 2.94Å; V70-L76 HydrophobicContact CG1-CB 4.45Å; V70-L76 HydrophobicContact CG1-CD1 4.45Å; V70-L76 HydrophobicContact CG1-CD2 4.08Å; V70-F78 HydrophobicContact CG1-CE1 4.49Å; V70-F78 HydrophobicContact CG1-CZ 4.01Å; V70-F78 HydrophobicContact CG2-CE1 4.33Å; V70-F78 HydrophobicContact CG2-CZ 4.05Å
71R92.3Very high94.4Very high135 Ų13564 Ų6451%0.50932%0.316SS..  trans-56129.4177.6-171.2168.7-178.9-133.29.6110.2V50 E73 L76V50-R71 VanDerWaalsContact O-CB 3.26Å; V50-R71 WeakPolarHBondContact O-CB 3.27Å; V50-R71 PolarHBondContact O-N 2.82Å; R71-E73 VanDerWaalsContact C-N 3.35Å; R71-E73 WeakPolarHBondContact CD-OE1 3.44Å; R71-E73 HydrophobicContact CG-CG 4.33Å; R71-E73 WeakPolarHBondContact CG-OE1 3.46Å; R71-E73 IonicContact CZ-OE1 3.67Å; R71-E73 IonicContact NE-OE1 2.77Å; R71-E73 PolarHBondContact NE-OE1 2.92Å; R71-E73 IonicContact NH1-OE1 2.84Å; R71-E73 PolarHBondContact NH1-OE1 2.83Å; R71-E73 PolarHBondContact O-N 2.84Å; R71-L76 VanDerWaalsContact O-CD2 3.3Å; R71-L76 WeakPolarHBondContact O-CD2 3.28Å
72K88.8Confident94.6Very high187 Ų18761.6 Ų61.681%0.81330%0.303SS*.  trans-74.982.8-173.1-67.9-177.7-179.3178.80112.1N52 V70N52-K72 PolarHBondContact OD1-N 3.04Å; V70-K72 PolarHBondContact O-N 2.94Å
73E91.9Very high94.7Very high68 Ų6860.1 Ų60.132%0.31829%0.294SS..  trans-116.5167.6175.9-70.4167.2-158.100110.8R71 P75 L76 Q77R71-E73 VanDerWaalsContact C-N 3.35Å; R71-E73 WeakPolarHBondContact CD-OE1 3.44Å; R71-E73 HydrophobicContact CG-CG 4.33Å; R71-E73 WeakPolarHBondContact CG-OE1 3.46Å; R71-E73 IonicContact CZ-OE1 3.67Å; R71-E73 IonicContact NE-OE1 2.77Å; R71-E73 PolarHBondContact NE-OE1 2.92Å; R71-E73 IonicContact NH1-OE1 2.84Å; R71-E73 PolarHBondContact NH1-OE1 2.83Å; R71-E73 PolarHBondContact O-N 2.84Å; E73-P75 CarbonylContact C-O 3.6Å; E73-P75 WeakPolarHBondContact CB-O 3.41Å; E73-L76 WeakPolarHBondContact O-CD2 3.36Å; E73-Q77 WeakPolarHBondContact OE2-CG 3.49Å
74N91.9Very high94.8Very high123 Ų12356.5 Ų56.566%0.65828%0.278SS*.SBendtrans-137.6106.1175.8179.727.7000109.1N6N6-N74 WeakPolarHBondContact CB-OD1 3.31Å; N6-N74 PolarHBondContact ND2-OD1 3.48Å
75P95Very high94.9Very high23 Ų2352.4 Ų52.415%0.14926%0.26CS..SBendcis-69.9161.3-2.729-33.8000113.5N6 R8 E73 Q77N6-P75 HydrophobicContact CB-CB 3.89Å; N6-P75 WeakPolarHBondContact O-CA 3.21Å; R8-P75 HydrophobicContact CB-CB 4.18Å; R8-P75 HydrophobicContact CB-CG 3.81Å; E73-P75 CarbonylContact C-O 3.6Å; E73-P75 WeakPolarHBondContact CB-O 3.41Å; P75-Q77 PolarHBondContact O-NE2 3.06Å
76L96.3Very high95Very high18 Ų1852.5 Ų52.59%0.09426%0.261CS..EExtended strand (participates in β ladder)trans-66.5130.9167.6-65.4-179.2000110I5 N6 V7 R8 V70 R71 E73 F78I5-L76 HydrophobicContact CG2-CD1 3.53Å; I5-L76 HydrophobicContact CG2-CG 3.97Å; N6-L76 PolarHBondContact O-N 2.84Å; V7-L76 HydrophobicContact CG2-CB 4.45Å; R8-L76 PolarHBondContact N-O 3.05Å; V70-L76 HydrophobicContact CG1-CB 4.45Å; V70-L76 HydrophobicContact CG1-CD1 4.45Å; V70-L76 HydrophobicContact CG1-CD2 4.08Å; R71-L76 VanDerWaalsContact O-CD2 3.3Å; R71-L76 WeakPolarHBondContact O-CD2 3.28Å; E73-L76 WeakPolarHBondContact O-CD2 3.36Å; L76-F78 HydrophobicContact CB-CE2 3.8Å
77Q97.3Very high95Very high67 Ų6750.1 Ų50.131%0.31324%0.242SC..EExtended strand (participates in β ladder)trans-94125.3-173.9-58.7-61.6-32.600112.7E73 P75E73-Q77 WeakPolarHBondContact OE2-CG 3.49Å; P75-Q77 PolarHBondContact O-NE2 3.06Å
78F98.1Very high95.1Very high3 Ų347.8 Ų47.81%0.01322%0.22CC..EExtended strand (participates in β ladder)trans-130.1145.3170-60-95.6000111.2V7 R8 V9 T10 L29 L47 Q48 Y49 L59 V65 V70 L76V7-F78 HydrophobicContact CG1-CD2 3.53Å; V7-F78 HydrophobicContact CG1-CE2 3.69Å; R8-F78 PolarHBondContact O-N 2.8Å; V9-F78 WeakPolarHBondContact CA-O 3.33Å; V9-F78 HydrophobicContact CG2-CB 4.31Å; T10-F78 PolarHBondContact N-O 3.31Å; L29-F78 HydrophobicContact CD2-CD2 4.4Å; L29-F78 HydrophobicContact CD2-CE1 4.42Å; L29-F78 HydrophobicContact CD2-CE2 4.08Å; L29-F78 HydrophobicContact CD2-CZ 4.11Å; L47-F78 HydrophobicContact CB-CD1 4.18Å; L47-F78 HydrophobicContact CD2-CB 4.18Å; Q48-F78 CarbonylContact O-C 3.49Å; Q48-F78 VanDerWaalsContact O-CA 3.27Å; Q48-F78 WeakPolarHBondContact O-CA 3.38Å; Y49-F78 HydrophobicContact CD1-CD1 4.27Å; Y49-F78 AromaticContact CD1-CE1 3.96Å; Y49-F78 HydrophobicContact CD1-CE1 3.96Å; Y49-F78 HydrophobicContact CG-CD1 4.32Å; Y49-F78 AromaticContact CG-CE1 4Å; Y49-F78 HydrophobicContact CG-CE1 4Å; L59-F78 HydrophobicContact CD1-CE1 4.09Å; L59-F78 HydrophobicContact CD2-CE1 4.34Å; V65-F78 HydrophobicContact CG1-CE1 4.47Å; V65-F78 HydrophobicContact CG1-CE2 4.36Å; V65-F78 HydrophobicContact CG1-CZ 3.65Å; V70-F78 HydrophobicContact CG1-CE1 4.49Å; V70-F78 HydrophobicContact CG1-CZ 4.01Å; V70-F78 HydrophobicContact CG2-CE1 4.33Å; V70-F78 HydrophobicContact CG2-CZ 4.05Å; L76-F78 HydrophobicContact CB-CE2 3.8Å
79K98.2Very high95.3Very high95 Ų9547.1 Ų47.141%0.41322%0.217SC..EExtended strand (participates in β ladder)trans-105.4124.1166.6-63.8-172175.1-168.50109.5T10 Q48 R81T10-K79 CarbonylContact O-C 3.57Å; T10-K79 WeakPolarHBondContact O-CA 3.49Å; Q48-K79 PolarHBondContact N-O 2.84Å; Q48-K79 PolarHBondContact O-N 3.02Å; K79-R81 HydrophobicContact CB-CG 4.09Å
80F98.4Very high95.4Very high1 Ų144 Ų440%0.00421%0.21CC..EExtended strand (participates in β ladder)trans-80.1122.6165.4-171.9-97.1000108.2V9 T10 T11 F30 V33 V34 I37 L39 F45 L47 L101V9-F80 HydrophobicContact CG1-CB 3.92Å; T10-F80 PolarHBondContact O-N 2.92Å; T11-F80 HydrophobicContact CG2-CB 4.18Å; T11-F80 HydrophobicContact CG2-CD1 4.4Å; F30-F80 HydrophobicContact CD2-CE2 4.2Å; F30-F80 HydrophobicContact CE2-CD2 4.47Å; F30-F80 AromaticContact CE2-CE2 3.67Å; F30-F80 HydrophobicContact CE2-CE2 3.67Å; F30-F80 HydrophobicContact CZ-CE2 4.21Å; V33-F80 HydrophobicContact CG1-CB 4.41Å; V33-F80 HydrophobicContact CG1-CD2 3.66Å; V33-F80 HydrophobicContact CG1-CE2 4.05Å; V33-F80 HydrophobicContact CG1-CG 4.07Å; V34-F80 HydrophobicContact CG1-CE2 3.6Å; V34-F80 HydrophobicContact CG1-CZ 3.67Å; I37-F80 HydrophobicContact CD1-CD1 4.35Å; I37-F80 HydrophobicContact CD1-CE1 3.87Å; I37-F80 HydrophobicContact CD1-CZ 4.25Å; L39-F80 HydrophobicContact CD1-CE1 4.41Å; F45-F80 HydrophobicContact CB-CE1 3.96Å; F45-F80 HydrophobicContact CB-CE2 3.8Å; F45-F80 HydrophobicContact CB-CZ 3.39Å; F45-F80 HydrophobicContact CD1-CD1 4.01Å; F45-F80 AromaticContact CD1-CE1 3.32Å; F45-F80 HydrophobicContact CD1-CE1 3.32Å; F45-F80 AromaticContact CD1-CZ 3.71Å; F45-F80 HydrophobicContact CD1-CZ 3.71Å; F45-F80 HydrophobicContact CD2-CE1 4.42Å; F45-F80 HydrophobicContact CD2-CZ 4.21Å; F45-F80 AromaticContact CE1-CE1 3.92Å; F45-F80 HydrophobicContact CE1-CE1 3.92Å; F45-F80 AromaticContact CG-CE1 3.64Å; F45-F80 HydrophobicContact CG-CE1 3.64Å; F45-F80 HydrophobicContact CG-CE2 4.37Å; F45-F80 AromaticContact CG-CZ 3.49Å; F45-F80 HydrophobicContact CG-CZ 3.49Å; F45-F80 VanDerWaalsContact CG-CZ 3.49Å; L47-F80 HydrophobicContact CD2-CB 4.08Å; L47-F80 HydrophobicContact CD2-CD2 3.96Å; L47-F80 HydrophobicContact CG-CD2 4.46Å; F80-L101 HydrophobicContact CD1-CD1 4.14Å; F80-L101 HydrophobicContact CE1-CD1 3.78Å
81R98Very high95.3Very high25 Ų2550.1 Ų50.19%0.09424%0.237CC..EExtended strand (participates in β ladder)trans-148.7148.9-172.5-73.5-66.4-175.6-85.516.6110.5T11 M12 F45 G46 W58 K79 K83 E108T11-R81 PolarHBondContact O-NH1 2.87Å; M12-R81 PolarHBondContact SD-NE 3.07Å; M12-R81 PolarHBondContact SD-NH2 2.83Å; F45-R81 WeakPolarHBondContact CA-O 3.22Å; G46-R81 PolarHBondContact N-O 3.14Å; G46-R81 PolarHBondContact O-N 3.49Å; G46-R81 VanDerWaalsContact O-N 3.11Å; W58-R81 HydrophobicContact CH2-CB 3.89Å; W58-R81 HydrophobicContact CZ3-CB 4.25Å; K79-R81 HydrophobicContact CB-CG 4.09Å; R81-K83 PolarHBondContact O-N 2.78Å; R81-E108 IonicContact CZ-OE2 2.8Å; R81-E108 IonicContact NE-OE2 2.72Å; R81-E108 PolarHBondContact NE-OE2 3.05Å; R81-E108 IonicContact NH2-OE1 2.72Å; R81-E108 IonicContact NH2-OE2 3.34Å; R81-E108 PolarHBondContact NH2-OE2 2.95Å
82A97.6Very high95.4Very high4 Ų445 Ų453%0.03322%0.219CC..EExtended strand (participates in β ladder)trans-63.8123.5165.200000109.1F45 F102 Q105F45-A82 HydrophobicContact CD1-CB 4.27Å; F45-A82 HydrophobicContact CE1-CB 4.08Å; A82-F102 HydrophobicContact CB-CD1 4.13Å; A82-F102 HydrophobicContact CB-CE1 3.61Å; A82-F102 HydrophobicContact CB-CE2 4.41Å; A82-F102 HydrophobicContact CB-CZ 3.78Å; A82-Q105 PolarHBondContact O-NE2 2.85Å
83K96.3Very high95.8Very high35 Ų3537 Ų3715%0.15219%0.185CC..SBendtrans-98.3-33.4177.8177.2-175.1168.3-153.90111.1Y44 W58 R81 Q282 L283Y44-K83 PolarHBondContact O-N 3.32Å; W58-K83 HydrophobicContact CD2-CB 4.41Å; W58-K83 HydrophobicContact CD2-CD 4Å; W58-K83 HydrophobicContact CD2-CG 4.08Å; W58-K83 HydrophobicContact CE3-CB 4.33Å; W58-K83 HydrophobicContact CE3-CD 4.35Å; W58-K83 HydrophobicContact CE3-CG 4.46Å; W58-K83 HydrophobicContact CG-CD 4.2Å; W58-K83 HydrophobicContact CH2-CB 3.65Å; W58-K83 HydrophobicContact CH2-CG 4.22Å; W58-K83 HydrophobicContact CZ2-CB 3.74Å; W58-K83 HydrophobicContact CZ2-CG 3.83Å; W58-K83 HydrophobicContact CZ3-CB 3.96Å; R81-K83 PolarHBondContact O-N 2.78Å; K83-Q282 PolarHBondContact NZ-O 3.27Å; K83-L283 HydrophobicContact CG-CD2 4.1Å
84F97.9Very high96Very high17 Ų1734.8 Ų34.88%0.07518%0.175CC..SBendtrans-121.9152.4177.1-54.5-73.3000109.1W43 Y44 F102 L283 L290W43-F84 WeakPolarHBondContact O-CD2 3.4Å; Y44-F84 PolarHBondContact O-N 2.69Å; F84-F102 WeakPolarHBondContact O-CZ 3.11Å; F84-L283 HydrophobicContact CE1-CD2 4.09Å; F84-L290 HydrophobicContact CB-CD1 3.6Å; F84-L290 HydrophobicContact CD2-CD1 4.33Å; F84-L290 HydrophobicContact CG-CD1 3.98Å
85F98Very high96.1Very high24 Ų2431 Ų3111%0.10515%0.153CC..  trans-114155.5-178.2-75-104.2000110.4F102 V106 Y201 R294F85-F102 HydrophobicContact CD1-CD1 4.1Å; F85-F102 AromaticContact CD1-CE1 3.66Å; F85-F102 HydrophobicContact CD1-CE1 3.66Å; F85-F102 HydrophobicContact CE1-CD1 4.15Å; F85-F102 AromaticContact CE1-CE1 4Å; F85-F102 HydrophobicContact CE1-CE1 4Å; F85-F102 HydrophobicContact CG-CE1 4.08Å; F85-V106 HydrophobicContact CE1-CG2 3.98Å; F85-Y201 AromaticContact CD1-CE1 3.92Å; F85-Y201 HydrophobicContact CD1-CE1 3.92Å; F85-Y201 HydrophobicContact CD1-CE2 4.22Å; F85-Y201 AromaticContact CD1-CZ 3.67Å; F85-Y201 HydrophobicContact CE1-CE2 4.24Å; F85-R294 PolarHBondContact O-NH2 2.75Å
86P96.6Very high96.1Very high4 Ų432.4 Ų32.43%0.02616%0.16CC..  trans-61.9158165.829.1-36.1000111Y44 V89 E92 L93Y44-P86 HydrophobicContact CE1-CB 4.42Å; P86-V89 HydrophobicContact CG-CB 4.35Å; P86-V89 HydrophobicContact CG-CG1 3.63Å; P86-E92 WeakPolarHBondContact CA-OE2 3.42Å; P86-E92 HydrophobicContact CB-CB 3.69Å; P86-E92 HydrophobicContact CB-CG 4.27Å; P86-L93 HydrophobicContact CB-CD2 4.38Å; P86-L93 HydrophobicContact CG-CD2 4.04Å; P86-L93 HydrophobicContact CG-CG 4.37Å
87E93.8Very high96.1Very high19 Ų1933.2 Ų33.29%0.08916%0.164CC..SBendtrans-72-53.9160.7-73.1174.5-129.500109.2E92 A222 L223 Y291 R294 R295 R517E87-E92 WeakPolarHBondContact CA-OE1 3.37Å; E87-E92 WeakPolarHBondContact CB-OE1 3.45Å; E87-E92 PolarHBondContact N-OE1 2.91Å; E87-A222 HydrophobicContact CG-CB 3.97Å; E87-L223 HydrophobicContact CB-CD2 4.11Å; E87-L223 HydrophobicContact CG-CD2 3.71Å; E87-Y291 WeakPolarHBondContact OE1-CD2 3.44Å; E87-R294 WeakPolarHBondContact OE1-CD 3.37Å; E87-R294 IonicContact OE1-CZ 3.61Å; E87-R294 IonicContact OE1-NE 3.44Å; E87-R294 IonicContact OE1-NH1 2.69Å; E87-R294 PolarHBondContact OE1-NH1 2.99Å; E87-R295 IonicContact OE1-CZ 2.6Å; E87-R295 IonicContact OE1-NH1 2.96Å; E87-R295 PolarHBondContact OE1-NH1 2.82Å; E87-R295 IonicContact OE1-NH2 2.68Å; E87-R295 IonicContact OE2-CZ 3.77Å; E87-R295 IonicContact OE2-NH1 3.63Å; E87-R295 PolarHBondContact OE2-NH1 3.46Å; E87-R295 IonicContact OE2-NH2 2.71Å; E87-R295 PolarHBondContact OE2-NH2 3.02Å; E87-R517 PolarHBondContact O-NH1 2.94Å; E87-R517 PolarHBondContact O-NH2 3.41Å
88D95.1Very high96.1Very high22 Ų2230 Ų3012%0.11815%0.149CC..  trans-123.7118.6171.1-152.5-47000112.6A90 E91 E92 Q196 R517 K523D88-A90 PolarHBondContact O-N 3.35Å; D88-A90 VanDerWaalsContact O-N 3.17Å; D88-A90 PolarHBondContact OD1-N 3.18Å; D88-E91 PolarHBondContact O-N 3.15Å; D88-E92 PolarHBondContact N-OE1 2.72Å; D88-E92 WeakPolarHBondContact O-CB 3.38Å; D88-E92 PolarHBondContact O-N 3.05Å; D88-Q196 PolarHBondContact OD1-NE2 3.21Å; D88-Q196 PolarHBondContact OD1-OE1 3Å; D88-R517 VanDerWaalsContact CB-NH2 3.34Å; D88-R517 IonicContact OD1-NH2 3.7Å; D88-R517 IonicContact OD2-CZ 2.76Å; D88-R517 IonicContact OD2-NE 2.67Å; D88-R517 IonicContact OD2-NH2 3.37Å; D88-R517 PolarHBondContact OD2-NH2 3Å; D88-K523 IonicContact OD2-NZ 3.84Å; D88-K523 PolarHBondContact OD2-NZ 2.89Å
89V96.6Very high96.1Very high0 Ų030.3 Ų30.30%015%0.15CC..Hα-helixtrans-60.7-26.2-176.4-590000113.5P86 L93 L189 L192 K193 Q196 Y201P86-V89 HydrophobicContact CG-CB 4.35Å; P86-V89 HydrophobicContact CG-CG1 3.63Å; V89-L93 HydrophobicContact CB-CD1 3.97Å; V89-L93 HydrophobicContact CB-CG 4.4Å; V89-L93 HydrophobicContact CG1-CD1 4.31Å; V89-L93 WeakPolarHBondContact O-CG 3.38Å; V89-L189 HydrophobicContact CG2-CD1 4.46Å; V89-L192 HydrophobicContact CB-CB 4.21Å; V89-L192 HydrophobicContact CG1-CB 4.21Å; V89-L192 HydrophobicContact CG2-CB 3.97Å; V89-K193 HydrophobicContact CG2-CB 4.33Å; V89-K193 HydrophobicContact CG2-CG 3.65Å; V89-Q196 HydrophobicContact CG1-CB 4.26Å; V89-Q196 HydrophobicContact CG2-CG 4.46Å; V89-Q196 VanDerWaalsContact N-OE1 3.11Å; V89-Y201 VanDerWaalsContact CG1-OH 3.25Å; V89-Y201 WeakPolarHBondContact CG1-OH 3.46Å
90A93.4Very high96.1Very high42 Ų4229.5 Ų29.535%0.34715%0.147SC..Hα-helixtrans-78.1-26.5-176.900000113.6D88 K193D88-A90 PolarHBondContact O-N 3.35Å; D88-A90 VanDerWaalsContact O-N 3.17Å; D88-A90 PolarHBondContact OD1-N 3.18Å; A90-K193 HydrophobicContact CB-CD 4.12Å; A90-K193 HydrophobicContact CB-CG 4.23Å
91E91.1Very high96.1Very high141 Ų14129.6 Ų29.666%0.65915%0.147SC*.Hα-helixtrans-102.8-20.9-175.3-61-62.3147.400112.9D88 K306D88-E91 PolarHBondContact O-N 3.15Å; E91-K306 PolarHBondContact O-NZ 2.93Å
92E94.4Very high96.1Very high27 Ų2728.4 Ų28.413%0.12614%0.143CC..Hα-helixtrans-109.8-23.1-169.4-84.4-175.5-113.200116.3Y44 P86 E87 D88 R294Y44-E92 WeakPolarHBondContact OH-CB 3.3Å; Y44-E92 PolarHBondContact OH-O 3.32Å; Y44-E92 PolarHBondContact OH-OE2 2.96Å; Y44-E92 VanDerWaalsContact OH-OE2 3.09Å; P86-E92 WeakPolarHBondContact CA-OE2 3.42Å; P86-E92 HydrophobicContact CB-CB 3.69Å; P86-E92 HydrophobicContact CB-CG 4.27Å; E87-E92 WeakPolarHBondContact CA-OE1 3.37Å; E87-E92 WeakPolarHBondContact CB-OE1 3.45Å; E87-E92 PolarHBondContact N-OE1 2.91Å; D88-E92 PolarHBondContact N-OE1 2.72Å; D88-E92 WeakPolarHBondContact O-CB 3.38Å; D88-E92 PolarHBondContact O-N 3.05Å; E92-R294 IonicContact OE1-CZ 3.84Å; E92-R294 IonicContact OE1-NE 2.75Å; E92-R294 PolarHBondContact OE1-NE 3Å; E92-R294 VanDerWaalsContact OE1-NE 3.1Å; E92-R294 IonicContact OE1-NH2 3.83Å; E92-R294 IonicContact OE2-CZ 2.78Å; E92-R294 IonicContact OE2-NE 3.17Å; E92-R294 PolarHBondContact OE2-NE 3.47Å; E92-R294 IonicContact OE2-NH2 2.76Å; E92-R294 PolarHBondContact OE2-NH2 2.95Å
93L96.7Very high96.2Very high19 Ų1928.7 Ų28.710%0.09914%0.143CC..  trans-91.9116.3-179.1-56.5-174.6000109.3Y44 P86 V89 T98 Q99 F102 L192Y44-L93 HydrophobicContact CD2-CD2 4.49Å; Y44-L93 HydrophobicContact CE2-CD2 3.95Å; P86-L93 HydrophobicContact CB-CD2 4.38Å; P86-L93 HydrophobicContact CG-CD2 4.04Å; P86-L93 HydrophobicContact CG-CG 4.37Å; V89-L93 HydrophobicContact CB-CD1 3.97Å; V89-L93 HydrophobicContact CB-CG 4.4Å; V89-L93 HydrophobicContact CG1-CD1 4.31Å; V89-L93 WeakPolarHBondContact O-CG 3.38Å; L93-T98 HydrophobicContact CD2-CG2 4.1Å; L93-Q99 HydrophobicContact CB-CG 4.36Å; L93-Q99 HydrophobicContact CD1-CG 4.12Å; L93-F102 HydrophobicContact CD1-CB 4.3Å; L93-F102 HydrophobicContact CD1-CD2 4.2Å; L93-F102 HydrophobicContact CD1-CG 4.34Å; L93-F102 HydrophobicContact CD2-CD2 3.77Å; L93-F102 HydrophobicContact CD2-CE2 3.74Å; L93-L192 HydrophobicContact CD1-CD1 3.9Å
94I95.5Very high96.3Very high22 Ų2228.8 Ų28.811%0.11315%0.145CC..  trans-101.6-43.9-166.4-53.8167000112.1E41 V302 M305 K306 A309E41-I94 HydrophobicContact CG-CB 4.45Å; E41-I94 HydrophobicContact CG-CD1 4.49Å; E41-I94 PolarHBondContact OE1-N 2.85Å; E41-I94 PolarHBondContact OE2-N 3.04Å; I94-V302 HydrophobicContact CD1-CG1 3.98Å; I94-M305 HydrophobicContact CD1-CB 4.38Å; I94-M305 HydrophobicContact CD1-CE 4.22Å; I94-M305 HydrophobicContact CG2-CB 4Å; I94-M305 WeakPolarHBondContact CG2-O 3.33Å; I94-K306 HydrophobicContact CD1-CG 3.9Å; I94-K306 HydrophobicContact CG1-CG 3.94Å; I94-K306 HydrophobicContact CG2-CG 4.12Å; I94-A309 HydrophobicContact CG2-CB 3.74Å; I94-A309 VanDerWaalsContact O-CB 3.24Å; I94-A309 WeakPolarHBondContact O-CB 3.35Å
95Q94.9Very high96.3Very high42 Ų4229.5 Ų29.520%0.19615%0.149CC..SBendtrans-102.2142.1-175.7-56.5-179-91.500112.4G38 E41 I97 T98 Q99 M305G38-Q95 PolarHBondContact O-NE2 2.86Å; E41-Q95 WeakPolarHBondContact OE1-CB 3.42Å; E41-Q95 WeakPolarHBondContact OE1-CG 3.22Å; E41-Q95 PolarHBondContact OE1-N 2.8Å; Q95-I97 HydrophobicContact CB-CG2 4.02Å; Q95-I97 PolarHBondContact O-N 2.68Å; Q95-I97 VanDerWaalsContact O-N 3.16Å; Q95-T98 WeakPolarHBondContact O-CB 3.42Å; Q95-T98 PolarHBondContact O-N 3.25Å; Q95-Q99 PolarHBondContact O-N 3.33Å; Q95-M305 HydrophobicContact CG-CE 4.45Å
96D94.7Very high96.3Very high53 Ų5328.4 Ų28.428%0.28314%0.144SC..Hα-helixtrans-53.8-37.7175.8-57.9-32.7000112.6Q99 K100 K316D96-Q99 PolarHBondContact O-N 3.49Å; D96-K100 WeakPolarHBondContact O-CB 3.32Å; D96-K100 PolarHBondContact O-N 3.2Å; D96-K316 IonicContact OD2-NZ 2.8Å; D96-K316 PolarHBondContact OD2-NZ 2.95Å
97I96.2Very high96.4Very high35 Ų3530.5 Ų30.518%0.17915%0.153CC..Hα-helixtrans-65.6-44.2177.5-176.659.7000112.4L39 Q95 Q99 K100 L101L39-I97 HydrophobicContact CB-CG2 4.22Å; L39-I97 HydrophobicContact CD1-CG1 4.5Å; L39-I97 HydrophobicContact CD1-CG2 4.5Å; L39-I97 HydrophobicContact CG-CG2 4.49Å; Q95-I97 HydrophobicContact CB-CG2 4.02Å; Q95-I97 PolarHBondContact O-N 2.68Å; Q95-I97 VanDerWaalsContact O-N 3.16Å; I97-Q99 VanDerWaalsContact C-N 3.33Å; I97-Q99 PolarHBondContact O-N 2.93Å; I97-K100 HydrophobicContact CD1-CD 4.44Å; I97-K100 PolarHBondContact O-N 2.93Å; I97-L101 HydrophobicContact CD1-CD1 4.43Å; I97-L101 HydrophobicContact CD1-CG 4.26Å; I97-L101 HydrophobicContact CG1-CD1 4.4Å; I97-L101 WeakPolarHBondContact O-CG 3.24Å; I97-L101 PolarHBondContact O-N 3.25Å
98T97.4Very high96.6Very high0 Ų033.5 Ų33.50%017%0.167CC..Hα-helixtrans-60-48.5175.1-57.50000110E41 Y44 F45 L93 Q95 K100 L101 F102E41-T98 HydrophobicContact CB-CG2 4.03Å; E41-T98 HydrophobicContact CG-CG2 4.49Å; E41-T98 WeakPolarHBondContact OE1-CB 3.22Å; E41-T98 WeakPolarHBondContact OE1-CG2 3.41Å; E41-T98 PolarHBondContact OE1-OG1 2.93Å; Y44-T98 HydrophobicContact CD2-CG2 4.22Å; F45-T98 HydrophobicContact CE2-CG2 3.93Å; F45-T98 HydrophobicContact CZ-CG2 4.09Å; L93-T98 HydrophobicContact CD2-CG2 4.1Å; Q95-T98 WeakPolarHBondContact O-CB 3.42Å; Q95-T98 PolarHBondContact O-N 3.25Å; T98-K100 PolarHBondContact O-N 2.9Å; T98-L101 PolarHBondContact O-N 3.2Å; T98-F102 HydrophobicContact CG2-CD2 3.92Å; T98-F102 HydrophobicContact CG2-CE2 4.04Å; T98-F102 WeakPolarHBondContact O-CD2 3.44Å; T98-F102 PolarHBondContact O-N 3.47Å
99Q97.7Very high96.8Very high9 Ų932.7 Ų32.74%0.04216%0.163CC..Hα-helixtrans-62.5-42.7-178.5-151.9-148-83.700111.7L93 Q95 D96 I97 F102 F103 D185 M188 L189 L192L93-Q99 HydrophobicContact CB-CG 4.36Å; L93-Q99 HydrophobicContact CD1-CG 4.12Å; Q95-Q99 PolarHBondContact O-N 3.33Å; D96-Q99 PolarHBondContact O-N 3.49Å; I97-Q99 VanDerWaalsContact C-N 3.33Å; I97-Q99 PolarHBondContact O-N 2.93Å; Q99-F102 PolarHBondContact O-N 3.48Å; Q99-F103 WeakPolarHBondContact O-CB 3.39Å; Q99-F103 PolarHBondContact O-N 3.26Å; Q99-D185 PolarHBondContact NE2-O 2.87Å; Q99-M188 VanDerWaalsContact NE2-CB 3.31Å; Q99-L189 HydrophobicContact CG-CD1 4.17Å; Q99-L189 VanDerWaalsContact NE2-N 3.13Å; Q99-L192 HydrophobicContact CG-CD1 4.17Å
100K98.1Very high96.9Very high78 Ų7832.8 Ų32.834%0.33916%0.164SC..Hα-helixtrans-61-45.6174.3-177.8-168.8-176.3-164.30112.1D13 D96 I97 T98 F103 L104 M188D13-K100 VanDerWaalsContact OD2-CE 3.25Å; D13-K100 WeakPolarHBondContact OD2-CE 3.35Å; D13-K100 IonicContact OD2-NZ 3.16Å; D13-K100 PolarHBondContact OD2-NZ 2.8Å; D96-K100 WeakPolarHBondContact O-CB 3.32Å; D96-K100 PolarHBondContact O-N 3.2Å; I97-K100 HydrophobicContact CD1-CD 4.44Å; I97-K100 PolarHBondContact O-N 2.93Å; T98-K100 PolarHBondContact O-N 2.9Å; K100-F103 PolarHBondContact O-N 2.86Å; K100-L104 HydrophobicContact CG-CD1 4.12Å; K100-L104 WeakPolarHBondContact O-CB 3.48Å; K100-L104 VanDerWaalsContact O-CG 3.31Å; K100-L104 WeakPolarHBondContact O-CG 3.5Å; K100-L104 PolarHBondContact O-N 3.15Å; K100-M188 HydrophobicContact CB-CE 4.01Å; K100-M188 HydrophobicContact CB-SD 3.98Å; K100-M188 HydrophobicContact CG-CE 4.34Å; K100-M188 HydrophobicContact CG-SD 3.96Å
101L98.4Very high97.1Very high3 Ų331.4 Ų31.42%0.01615%0.151CC..Hα-helixtrans-66.4-40.4178.6-69.9179.4000112M12 D13 I37 L39 F45 F80 I97 T98 Q105M12-L101 HydrophobicContact CB-CD2 3.79Å; M12-L101 HydrophobicContact CG-CD2 4.05Å; D13-L101 WeakPolarHBondContact OD1-CD2 3.38Å; I37-L101 HydrophobicContact CD1-CD1 4.02Å; L39-L101 HydrophobicContact CD1-CD1 3.82Å; F45-L101 HydrophobicContact CE1-CB 4.01Å; F45-L101 HydrophobicContact CE1-CD1 4.07Å; F45-L101 HydrophobicContact CZ-CB 4.21Å; F45-L101 HydrophobicContact CZ-CD1 4.34Å; F80-L101 HydrophobicContact CD1-CD1 4.14Å; F80-L101 HydrophobicContact CE1-CD1 3.78Å; I97-L101 HydrophobicContact CD1-CD1 4.43Å; I97-L101 HydrophobicContact CD1-CG 4.26Å; I97-L101 HydrophobicContact CG1-CD1 4.4Å; I97-L101 WeakPolarHBondContact O-CG 3.24Å; I97-L101 PolarHBondContact O-N 3.25Å; T98-L101 PolarHBondContact O-N 3.2Å; L101-Q105 WeakPolarHBondContact O-CB 3.5Å; L101-Q105 PolarHBondContact O-N 2.92Å
102F98.6Very high97.4Very high0 Ų027.2 Ų27.20%014%0.137CC..Hα-helixtrans-61.7-49.9171.4-92.9-75.1000111.8Y44 F45 A82 F84 F85 L93 T98 Q99 L104 Q105 V106 L192Y44-F102 HydrophobicContact CD1-CE2 4.34Å; Y44-F102 AromaticContact CD1-CZ 3.97Å; Y44-F102 HydrophobicContact CD1-CZ 3.97Å; Y44-F102 AromaticContact CD2-CE2 3.75Å; Y44-F102 HydrophobicContact CD2-CE2 3.75Å; Y44-F102 HydrophobicContact CD2-CZ 4.22Å; Y44-F102 HydrophobicContact CE2-CE2 4.43Å; Y44-F102 AromaticContact CG-CE2 3.7Å; Y44-F102 HydrophobicContact CG-CE2 3.7Å; Y44-F102 AromaticContact CG-CZ 3.7Å; Y44-F102 HydrophobicContact CG-CZ 3.7Å; F45-F102 HydrophobicContact CE2-CE2 4.38Å; F45-F102 HydrophobicContact CZ-CD2 4.17Å; F45-F102 HydrophobicContact CZ-CE2 4.04Å; A82-F102 HydrophobicContact CB-CD1 4.13Å; A82-F102 HydrophobicContact CB-CE1 3.61Å; A82-F102 HydrophobicContact CB-CE2 4.41Å; A82-F102 HydrophobicContact CB-CZ 3.78Å; F84-F102 WeakPolarHBondContact O-CZ 3.11Å; F85-F102 HydrophobicContact CD1-CD1 4.1Å; F85-F102 AromaticContact CD1-CE1 3.66Å; F85-F102 HydrophobicContact CD1-CE1 3.66Å; F85-F102 HydrophobicContact CE1-CD1 4.15Å; F85-F102 AromaticContact CE1-CE1 4Å; F85-F102 HydrophobicContact CE1-CE1 4Å; F85-F102 HydrophobicContact CG-CE1 4.08Å; L93-F102 HydrophobicContact CD1-CB 4.3Å; L93-F102 HydrophobicContact CD1-CD2 4.2Å; L93-F102 HydrophobicContact CD1-CG 4.34Å; L93-F102 HydrophobicContact CD2-CD2 3.77Å; L93-F102 HydrophobicContact CD2-CE2 3.74Å; T98-F102 HydrophobicContact CG2-CD2 3.92Å; T98-F102 HydrophobicContact CG2-CE2 4.04Å; T98-F102 WeakPolarHBondContact O-CD2 3.44Å; T98-F102 PolarHBondContact O-N 3.47Å; Q99-F102 PolarHBondContact O-N 3.48Å; F102-L104 VanDerWaalsContact C-N 3.35Å; F102-L104 PolarHBondContact O-N 2.98Å; F102-Q105 PolarHBondContact O-N 3.2Å; F102-V106 WeakPolarHBondContact O-CB 3.39Å; F102-V106 VanDerWaalsContact O-CG2 3.25Å; F102-V106 WeakPolarHBondContact O-CG2 3.42Å; F102-V106 PolarHBondContact O-N 3.16Å; F102-L192 HydrophobicContact CB-CD1 3.91Å; F102-L192 HydrophobicContact CB-CD2 4.27Å
103F98.7Very high97.5Very high11 Ų1128.4 Ų28.45%0.04814%0.144CC..Hα-helixtrans-54.2-50178158.8-103.3000111.4Q99 K100 K107 A129 A132 M188 Y191 L192Q99-F103 WeakPolarHBondContact O-CB 3.39Å; Q99-F103 PolarHBondContact O-N 3.26Å; K100-F103 PolarHBondContact O-N 2.86Å; F103-K107 HydrophobicContact CE2-CD 4.31Å; F103-K107 HydrophobicContact CZ-CD 3.99Å; F103-K107 WeakPolarHBondContact O-CB 3.39Å; F103-K107 PolarHBondContact O-N 2.87Å; F103-A129 HydrophobicContact CE2-CB 4.22Å; F103-A129 HydrophobicContact CZ-CB 4.02Å; F103-A132 HydrophobicContact CE1-CB 4.31Å; F103-A132 HydrophobicContact CE2-CB 4.48Å; F103-A132 HydrophobicContact CZ-CB 3.91Å; F103-M188 HydrophobicContact CB-CB 3.95Å; F103-M188 HydrophobicContact CB-CG 4.18Å; F103-M188 HydrophobicContact CB-SD 4.32Å; F103-M188 HydrophobicContact CD1-CB 4.21Å; F103-M188 HydrophobicContact CD1-CG 3.5Å; F103-M188 VanDerWaalsContact CD1-CG 3.5Å; F103-M188 HydrophobicContact CD1-SD 3.45Å; F103-M188 WeakPolarHBondContact CD1-SD 3.46Å; F103-M188 HydrophobicContact CD2-CB 4.08Å; F103-M188 HydrophobicContact CD2-CG 4.01Å; F103-M188 HydrophobicContact CE1-CG 3.79Å; F103-M188 HydrophobicContact CE1-SD 3.95Å; F103-M188 HydrophobicContact CE2-CG 4.25Å; F103-M188 HydrophobicContact CG-CB 3.82Å; F103-M188 HydrophobicContact CG-CG 3.62Å; F103-M188 HydrophobicContact CG-SD 4.01Å; F103-M188 HydrophobicContact CZ-CG 4.16Å; F103-Y191 AromaticContact CD2-CD1 3.68Å; F103-Y191 HydrophobicContact CD2-CD1 3.68Å; F103-Y191 HydrophobicContact CD2-CD2 4.11Å; F103-Y191 HydrophobicContact CD2-CE1 4.33Å; F103-Y191 AromaticContact CD2-CG 3.6Å; F103-Y191 HydrophobicContact CD2-CG 3.6Å; F103-Y191 HydrophobicContact CE2-CD1 4.03Å; F103-Y191 AromaticContact CE2-CD2 3.61Å; F103-Y191 HydrophobicContact CE2-CD2 3.61Å; F103-Y191 HydrophobicContact CE2-CE2 4.11Å; F103-Y191 AromaticContact CE2-CG 3.58Å; F103-Y191 HydrophobicContact CE2-CG 3.58Å; F103-L192 HydrophobicContact CB-CD1 4.15Å; F103-L192 HydrophobicContact CB-CG 4.27Å
104L98.4Very high97.5Very high37 Ų3734.7 Ų34.719%0.19417%0.173CC..Hα-helixtrans-66.3-39.9-179.5-68.5172.6000112.5M12 D13 K100 F102 K107 E108M12-L104 HydrophobicContact CB-CB 3.53Å; M12-L104 HydrophobicContact CB-CD1 3.71Å; M12-L104 HydrophobicContact CB-CG 4.28Å; M12-L104 HydrophobicContact CE-CB 4.04Å; M12-L104 HydrophobicContact CG-CB 3.88Å; D13-L104 HydrophobicContact CB-CD1 3.86Å; K100-L104 HydrophobicContact CG-CD1 4.12Å; K100-L104 WeakPolarHBondContact O-CB 3.48Å; K100-L104 VanDerWaalsContact O-CG 3.31Å; K100-L104 WeakPolarHBondContact O-CG 3.5Å; K100-L104 PolarHBondContact O-N 3.15Å; F102-L104 VanDerWaalsContact C-N 3.35Å; F102-L104 PolarHBondContact O-N 2.98Å; L104-K107 PolarHBondContact O-N 3.34Å; L104-E108 PolarHBondContact O-N 2.99Å
105Q98.5Very high97.7Very high32 Ų3234.6 Ų34.615%0.1517%0.173CC..Hα-helixtrans-69.2-40.7178.9-175.4174.8-44.700112.2M12 A82 L101 F102 K107 E108 G109M12-Q105 HydrophobicContact CE-CB 4.45Å; M12-Q105 HydrophobicContact CG-CB 4.15Å; M12-Q105 HydrophobicContact SD-CB 3.73Å; M12-Q105 HydrophobicContact SD-CG 4.24Å; A82-Q105 PolarHBondContact O-NE2 2.85Å; L101-Q105 WeakPolarHBondContact O-CB 3.5Å; L101-Q105 PolarHBondContact O-N 2.92Å; F102-Q105 PolarHBondContact O-N 3.2Å; Q105-K107 VanDerWaalsContact C-N 3.34Å; Q105-E108 WeakPolarHBondContact O-CB 3.31Å; Q105-E108 PolarHBondContact O-N 3.22Å; Q105-G109 PolarHBondContact O-N 2.79Å
106V98.6Very high97.8Very high1 Ų132.7 Ų32.71%0.00616%0.164CC..Hα-helixtrans-68.1-38176.1175.60000110.1F85 F102 G109 I110 I115 Y191 L192 A195 Y201F85-V106 HydrophobicContact CE1-CG2 3.98Å; F102-V106 WeakPolarHBondContact O-CB 3.39Å; F102-V106 VanDerWaalsContact O-CG2 3.25Å; F102-V106 WeakPolarHBondContact O-CG2 3.42Å; F102-V106 PolarHBondContact O-N 3.16Å; V106-G109 PolarHBondContact O-N 3.35Å; V106-I110 HydrophobicContact CG1-CD1 3.9Å; V106-I110 WeakPolarHBondContact O-CG1 3.44Å; V106-I110 PolarHBondContact O-N 2.64Å; V106-I115 HydrophobicContact CG1-CD1 4.49Å; V106-Y191 HydrophobicContact CG1-CE1 4.24Å; V106-L192 HydrophobicContact CB-CD2 4.02Å; V106-L192 HydrophobicContact CG1-CD2 4.36Å; V106-L192 HydrophobicContact CG2-CD2 3.82Å; V106-A195 HydrophobicContact CG1-CB 3.71Å; V106-Y201 HydrophobicContact CG1-CD2 4.02Å; V106-Y201 HydrophobicContact CG1-CE2 3.96Å; V106-Y201 HydrophobicContact CG2-CD2 4.27Å; V106-Y201 HydrophobicContact CG2-CE2 3.65Å
107K98.5Very high98Very high47 Ų4730.2 Ų30.220%0.20415%0.15CC..Hα-helixtrans-65.8-36.7172.2-166.3-17880.471.40112.5F103 L104 Q105 L111 A129 Y191F103-K107 HydrophobicContact CE2-CD 4.31Å; F103-K107 HydrophobicContact CZ-CD 3.99Å; F103-K107 WeakPolarHBondContact O-CB 3.39Å; F103-K107 PolarHBondContact O-N 2.87Å; L104-K107 PolarHBondContact O-N 3.34Å; Q105-K107 VanDerWaalsContact C-N 3.34Å; K107-L111 HydrophobicContact CD-CD1 4.42Å; K107-L111 HydrophobicContact CG-CD1 3.81Å; K107-L111 HydrophobicContact CG-CG 4.24Å; K107-L111 VanDerWaalsContact O-CB 3.29Å; K107-L111 WeakPolarHBondContact O-CB 2.92Å; K107-L111 WeakPolarHBondContact O-CD1 3.05Å; K107-L111 WeakPolarHBondContact O-CG 3.34Å; K107-L111 PolarHBondContact O-N 3.29Å; K107-A129 HydrophobicContact CD-CB 3.78Å; K107-Y191 WeakPolarHBondContact CA-OH 3.19Å; K107-Y191 HydrophobicContact CB-CE1 4.24Å; K107-Y191 HydrophobicContact CD-CE2 4.5Å; K107-Y191 HydrophobicContact CG-CE2 4.3Å
108E97.9Very high98.1Very high83 Ų8328.8 Ų28.839%0.38814%0.143SC..Hα-helixtrans-57.1-55.4170-179.8177.5-155.200109.6M12 R81 L104 Q105 I110 L111 S112M12-E108 HydrophobicContact CE-CB 4.05Å; M12-E108 WeakPolarHBondContact CE-OE2 3.45Å; R81-E108 IonicContact CZ-OE2 2.8Å; R81-E108 IonicContact NE-OE2 2.72Å; R81-E108 PolarHBondContact NE-OE2 3.05Å; R81-E108 IonicContact NH2-OE1 2.72Å; R81-E108 IonicContact NH2-OE2 3.34Å; R81-E108 PolarHBondContact NH2-OE2 2.95Å; L104-E108 PolarHBondContact O-N 2.99Å; Q105-E108 WeakPolarHBondContact O-CB 3.31Å; Q105-E108 PolarHBondContact O-N 3.22Å; E108-I110 PolarHBondContact O-N 3.32Å; E108-L111 PolarHBondContact O-N 3.22Å; E108-S112 WeakPolarHBondContact O-CB 3.35Å; E108-S112 PolarHBondContact O-N 3.29Å; E108-S112 PolarHBondContact O-OG 2.82Å
109G98Very high98.1Very high4 Ų429 Ų294%0.04114%0.144CC..Hα-helixtrans-63.4-35-176.900000115.1Q105 V106 S112 E114 I115Q105-G109 PolarHBondContact O-N 2.79Å; V106-G109 PolarHBondContact O-N 3.35Å; G109-S112 WeakPolarHBondContact CA-OG 3.26Å; G109-S112 PolarHBondContact O-OG 2.99Å; G109-S112 VanDerWaalsContact O-OG 3.13Å; G109-E114 PolarHBondContact O-N 3.13Å; G109-I115 PolarHBondContact O-N 3.45Å
110I98.6Very high98.1Very high3 Ų329.9 Ų29.92%0.01515%0.149CC..Hα-helixtrans-71.4-47.8174.3-71.2171.1000110.5V106 E108 S112 D113 I115 C117 L125 P154 Y191 A195 L198V106-I110 HydrophobicContact CG1-CD1 3.9Å; V106-I110 WeakPolarHBondContact O-CG1 3.44Å; V106-I110 PolarHBondContact O-N 2.64Å; E108-I110 PolarHBondContact O-N 3.32Å; I110-S112 PolarHBondContact O-N 2.81Å; I110-D113 PolarHBondContact O-N 3.06Å; I110-D113 VanDerWaalsContact O-N 3.11Å; I110-I115 HydrophobicContact CG1-CB 3.92Å; I110-I115 HydrophobicContact CG1-CD1 4.41Å; I110-I115 HydrophobicContact CG1-CG2 3.96Å; I110-C117 HydrophobicContact CG2-CB 3.81Å; I110-L125 HydrophobicContact CD1-CD1 3.77Å; I110-P154 HydrophobicContact CG2-CG 4.21Å; I110-P154 WeakPolarHBondContact O-CG 3.46Å; I110-Y191 HydrophobicContact CD1-CE1 4.32Å; I110-A195 HydrophobicContact CD1-CB 4.02Å; I110-L198 HydrophobicContact CD1-CD1 3.63Å; I110-L198 HydrophobicContact CG1-CD1 4.11Å
111L98.2Very high98.1Very high13 Ų1327 Ų277%0.06814%0.137CC..Hα-helixtrans-66.9-26.4-177.4-68.2175000113.1K107 E108 D113 R151 L152K107-L111 HydrophobicContact CD-CD1 4.42Å; K107-L111 HydrophobicContact CG-CD1 3.81Å; K107-L111 HydrophobicContact CG-CG 4.24Å; K107-L111 VanDerWaalsContact O-CB 3.29Å; K107-L111 WeakPolarHBondContact O-CB 2.92Å; K107-L111 WeakPolarHBondContact O-CD1 3.05Å; K107-L111 WeakPolarHBondContact O-CG 3.34Å; K107-L111 PolarHBondContact O-N 3.29Å; E108-L111 PolarHBondContact O-N 3.22Å; L111-D113 VanDerWaalsContact C-N 3.35Å; L111-R151 HydrophobicContact CD1-CG 4.34Å; L111-R151 WeakPolarHBondContact CD1-O 3.15Å; L111-R151 HydrophobicContact CD2-CG 4.33Å; L111-R151 PolarHBondContact O-NE 3.5Å; L111-R151 PolarHBondContact O-NH2 3.47Å; L111-L152 VanDerWaalsContact CD2-C 3.43Å
112S97.5Very high98.1Very high53 Ų5327 Ų2737%0.37114%0.138SC..THydrogen-bonded Turntrans-84.2-2.2175.263.10000114.5E108 G109 I110 E114E108-S112 WeakPolarHBondContact O-CB 3.35Å; E108-S112 PolarHBondContact O-N 3.29Å; E108-S112 PolarHBondContact O-OG 2.82Å; G109-S112 WeakPolarHBondContact CA-OG 3.26Å; G109-S112 PolarHBondContact O-OG 2.99Å; G109-S112 VanDerWaalsContact O-OG 3.13Å; I110-S112 PolarHBondContact O-N 2.81Å; S112-E114 PolarHBondContact O-N 2.87Å; S112-E114 WeakPolarHBondContact OG-CG 3.47Å; S112-E114 PolarHBondContact OG-N 3.03Å
113D96.9Very high98.1Very high52 Ų5227 Ų2728%0.27814%0.138SC..THydrogen-bonded Turntrans58.120.5-169.4-75.6-71000114I110 L111 I115 P154 R156I110-D113 PolarHBondContact O-N 3.06Å; I110-D113 VanDerWaalsContact O-N 3.11Å; L111-D113 VanDerWaalsContact C-N 3.35Å; D113-I115 VanDerWaalsContact C-N 3.31Å; D113-P154 VanDerWaalsContact OD2-CB 3.22Å; D113-P154 WeakPolarHBondContact OD2-CB 3.3Å; D113-R156 IonicContact OD1-CZ 3.81Å; D113-R156 VanDerWaalsContact OD1-CZ 3.22Å; D113-R156 IonicContact OD1-NE 3.81Å; D113-R156 PolarHBondContact OD1-NE 2.71Å; D113-R156 IonicContact OD1-NH2 2.74Å; D113-R156 PolarHBondContact OD1-NH2 2.71Å
114E96.8Very high98.1Very high150 Ų15026.4 Ų26.470%0.70114%0.136SC*.SBendtrans-67.7-33.7165.4-76.1-173.2176.400111.7G109 S112 M200G109-E114 PolarHBondContact O-N 3.13Å; S112-E114 PolarHBondContact O-N 2.87Å; S112-E114 WeakPolarHBondContact OG-CG 3.47Å; S112-E114 PolarHBondContact OG-N 3.03Å; E114-M200 WeakPolarHBondContact O-CE 3.35Å
115I98.3Very high98.1Very high20 Ų2024.8 Ų24.810%0.10313%0.127CC..SBendtrans-110.5113.1171.3-57.4174.9000106.9V106 G109 I110 D113 C117 L198 M200V106-I115 HydrophobicContact CG1-CD1 4.49Å; G109-I115 PolarHBondContact O-N 3.45Å; I110-I115 HydrophobicContact CG1-CB 3.92Å; I110-I115 HydrophobicContact CG1-CD1 4.41Å; I110-I115 HydrophobicContact CG1-CG2 3.96Å; D113-I115 VanDerWaalsContact C-N 3.31Å; I115-C117 PolarHBondContact O-N 2.86Å; I115-L198 HydrophobicContact CG2-CB 4.33Å; I115-L198 HydrophobicContact CG2-CD1 4Å; I115-M200 HydrophobicContact CG2-CB 4.22Å
116Y98.4Very high98.1Very high3 Ų323.3 Ų23.31%0.01212%0.12CC..  trans-59.1137172.8171.7-94.3000110.9P118 R156 M200 L234 N550 H554Y116-P118 HydrophobicContact CE1-CB 4.46Å; Y116-R156 VanDerWaalsContact CE2-NH1 3.27Å; Y116-M200 VanDerWaalsContact CB-SD 3.55Å; Y116-M200 PolarHBondContact N-SD 2.74Å; Y116-L234 HydrophobicContact CD1-CD1 3.89Å; Y116-L234 HydrophobicContact CD1-CD2 3.93Å; Y116-L234 HydrophobicContact CE1-CD1 4.09Å; Y116-L234 HydrophobicContact CG-CD1 4.36Å; Y116-L234 HydrophobicContact CG-CD2 4.08Å; Y116-N550 HydrophobicContact CD2-CB 3.45Å; Y116-N550 VanDerWaalsContact CD2-CB 3.45Å; Y116-N550 HydrophobicContact CE2-CB 3.78Å; Y116-N550 HydrophobicContact CG-CB 4.04Å; Y116-H554 HydrophobicContact CE1-CB 3.56Å; Y116-H554 AromaticContact CE1-CG 3.57Å; Y116-H554 AromaticContact CE1-ND1 3.76Å; Y116-H554 AromaticContact CZ-CG 3.95Å; Y116-H554 WeakPolarHBondContact OH-CB 3.44Å
117C98.4Very high98Very high0 Ų023.2 Ų23.20%012%0.12CC..  trans-143.9126.9177.8-173.10000109.4I110 I115 R156 L198I110-C117 HydrophobicContact CG2-CB 3.81Å; I115-C117 PolarHBondContact O-N 2.86Å; C117-R156 PolarHBondContact O-NH1 2.95Å; C117-R156 VanDerWaalsContact O-NH1 3.07Å; C117-R156 PolarHBondContact O-NH2 2.91Å; C117-L198 HydrophobicContact CB-CD1 4.02Å; C117-L198 HydrophobicContact CB-CD2 4.4Å
118P98Very high98.1Very high5 Ų521.2 Ų21.23%0.03211%0.111CC..  trans-70.4156.8179.830.1-35.5000111.7Y116 E120 T121 A122Y116-P118 HydrophobicContact CE1-CB 4.46Å; P118-E120 PolarHBondContact O-N 3.49Å; P118-T121 PolarHBondContact O-N 3.44Å; P118-A122 WeakPolarHBondContact O-CB 3.42Å; P118-A122 PolarHBondContact O-N 2.93Å
119P97.9Very high98.1Very high4 Ų417.7 Ų17.73%0.02610%0.096CC..Hα-helixtrans-53.9-48.9-171.6-29.937.4000115.3A122 V123 V157 L538P119-A122 WeakPolarHBondContact O-CB 3.48Å; P119-A122 PolarHBondContact O-N 2.98Å; P119-V123 WeakPolarHBondContact O-CG2 3.48Å; P119-V123 PolarHBondContact O-N 3.35Å; P119-V157 HydrophobicContact CB-CG1 3.92Å; P119-V157 HydrophobicContact CG-CG1 4.46Å; P119-L538 HydrophobicContact CB-CD1 3.86Å
120E97.3Very high98.1Very high29 Ų2917.5 Ų17.514%0.1369%0.094CC..Hα-helixtrans-58.2-48.5178.439.6-93.7-11400112.2P118 A122 V123 L124 L534 S535 R542P118-E120 PolarHBondContact O-N 3.49Å; E120-A122 VanDerWaalsContact C-N 3.34Å; E120-A122 PolarHBondContact O-N 3.37Å; E120-V123 PolarHBondContact O-N 3.01Å; E120-L124 PolarHBondContact O-N 3.13Å; E120-L124 VanDerWaalsContact O-N 3.13Å; E120-L534 HydrophobicContact CB-CB 3.85Å; E120-S535 VanDerWaalsContact OE1-CB 3.24Å; E120-S535 WeakPolarHBondContact OE1-CB 3.44Å; E120-S535 PolarHBondContact OE1-OG 2.88Å; E120-R542 IonicContact OE2-CZ 2.8Å; E120-R542 IonicContact OE2-NH2 3.39Å; E120-R542 PolarHBondContact OE2-NH2 2.89Å
121T98.3Very high98.1Very high16 Ų1617.4 Ų17.410%0.0989%0.094CC..Hα-helixtrans-65.4-38.1175.8-54.30000111.5P118 V123 L124 L125 I194 L198P118-T121 PolarHBondContact O-N 3.44Å; T121-V123 PolarHBondContact O-N 3.46Å; T121-L124 PolarHBondContact O-N 3.29Å; T121-L125 HydrophobicContact CG2-CD1 3.89Å; T121-L125 HydrophobicContact CG2-CG 4.08Å; T121-L125 VanDerWaalsContact O-CB 3.26Å; T121-L125 WeakPolarHBondContact O-CB 3.44Å; T121-L125 VanDerWaalsContact O-CG 3.22Å; T121-L125 WeakPolarHBondContact O-CG 3.45Å; T121-L125 PolarHBondContact O-N 2.7Å; T121-I194 HydrophobicContact CG2-CG2 3.64Å; T121-L198 HydrophobicContact CG2-CD2 4.26Å
122A98.3Very high98Very high3 Ų317.3 Ų17.33%0.02510%0.095CC..Hα-helixtrans-61.9-41.917800000112.4P118 P119 E120 G126 I153 P154 V157P118-A122 WeakPolarHBondContact O-CB 3.42Å; P118-A122 PolarHBondContact O-N 2.93Å; P119-A122 WeakPolarHBondContact O-CB 3.48Å; P119-A122 PolarHBondContact O-N 2.98Å; E120-A122 VanDerWaalsContact C-N 3.34Å; E120-A122 PolarHBondContact O-N 3.37Å; A122-G126 PolarHBondContact O-N 3.3Å; A122-I153 HydrophobicContact CB-CG2 4.2Å; A122-I153 WeakPolarHBondContact O-CG2 3.45Å; A122-P154 HydrophobicContact CB-CG 4.44Å; A122-V157 HydrophobicContact CB-CG1 4.49Å; A122-V157 HydrophobicContact CB-CG2 4.08Å
123V98.1Very high98Very high0 Ų019.9 Ų19.90%010%0.099CC..Hα-helixtrans-67.1-44.2175.9178.10000111.5P119 E120 T121 G126 S127 I153 W168 I172 L534 L538P119-V123 WeakPolarHBondContact O-CG2 3.48Å; P119-V123 PolarHBondContact O-N 3.35Å; E120-V123 PolarHBondContact O-N 3.01Å; T121-V123 PolarHBondContact O-N 3.46Å; V123-G126 WeakPolarHBondContact O-CA 3.44Å; V123-G126 PolarHBondContact O-N 2.82Å; V123-G126 VanDerWaalsContact O-N 3.16Å; V123-S127 PolarHBondContact O-N 2.92Å; V123-I153 HydrophobicContact CG2-CG2 4.41Å; V123-W168 HydrophobicContact CG2-CE3 4.15Å; V123-W168 HydrophobicContact CG2-CZ3 3.55Å; V123-I172 HydrophobicContact CG1-CG1 4.04Å; V123-L534 HydrophobicContact CB-CD1 4.38Å; V123-L534 HydrophobicContact CB-CD2 3.86Å; V123-L534 HydrophobicContact CG1-CD1 4.38Å; V123-L534 HydrophobicContact CG1-CD2 3.51Å; V123-L538 HydrophobicContact CG2-CD1 4.07Å
124L98.4Very high97.9Very high0 Ų020.5 Ų20.50%010%0.1CC..Hα-helixtrans-61.5-48.1178.3-175.356.2000111E120 T121 G126 S127 Y128 I194 V527 Q530 L531 L534E120-L124 PolarHBondContact O-N 3.13Å; E120-L124 VanDerWaalsContact O-N 3.13Å; T121-L124 PolarHBondContact O-N 3.29Å; L124-G126 VanDerWaalsContact C-N 3.31Å; L124-G126 PolarHBondContact O-N 3.07Å; L124-S127 PolarHBondContact O-N 3.35Å; L124-S127 VanDerWaalsContact O-N 3.13Å; L124-S127 PolarHBondContact O-OG 3.27Å; L124-Y128 HydrophobicContact CD1-CD2 4.26Å; L124-Y128 HydrophobicContact CD1-CE2 3.73Å; L124-Y128 HydrophobicContact CD2-CE2 4.4Å; L124-Y128 HydrophobicContact CG-CD2 4.15Å; L124-Y128 HydrophobicContact CG-CE2 3.77Å; L124-Y128 VanDerWaalsContact O-CD2 3.28Å; L124-Y128 WeakPolarHBondContact O-CD2 3.44Å; L124-Y128 PolarHBondContact O-N 3.15Å; L124-Y128 VanDerWaalsContact O-N 3.12Å; L124-I194 HydrophobicContact CD2-CD1 3.94Å; L124-I194 HydrophobicContact CG-CD1 4.3Å; L124-V527 HydrophobicContact CD2-CG1 4.31Å; L124-Q530 HydrophobicContact CD1-CB 4.11Å; L124-Q530 HydrophobicContact CD2-CB 4.04Å; L124-L531 HydrophobicContact CB-CD2 4.31Å; L124-L531 HydrophobicContact CD2-CD2 3.68Å; L124-L531 HydrophobicContact CD2-CG 3.86Å; L124-L534 HydrophobicContact CB-CD1 3.73Å; L124-L534 HydrophobicContact CD1-CD1 4.46Å
125L98.7Very high97.9Very high2 Ų213.9 Ų13.91%0.017%0.071CC..Hα-helixtrans-58.8-40.6172.6-73.1-178.5000112I110 T121 S127 Y128 A129 Y191 I194 A195I110-L125 HydrophobicContact CD1-CD1 3.77Å; T121-L125 HydrophobicContact CG2-CD1 3.89Å; T121-L125 HydrophobicContact CG2-CG 4.08Å; T121-L125 VanDerWaalsContact O-CB 3.26Å; T121-L125 WeakPolarHBondContact O-CB 3.44Å; T121-L125 VanDerWaalsContact O-CG 3.22Å; T121-L125 WeakPolarHBondContact O-CG 3.45Å; T121-L125 PolarHBondContact O-N 2.7Å; L125-S127 VanDerWaalsContact C-N 3.33Å; L125-S127 PolarHBondContact O-N 3.09Å; L125-Y128 PolarHBondContact O-N 3Å; L125-A129 WeakPolarHBondContact O-CB 3.39Å; L125-A129 PolarHBondContact O-N 3.38Å; L125-Y191 HydrophobicContact CB-CD2 3.96Å; L125-Y191 HydrophobicContact CB-CE2 3.53Å; L125-Y191 HydrophobicContact CD2-CD1 4.04Å; L125-Y191 HydrophobicContact CD2-CD2 3.76Å; L125-Y191 HydrophobicContact CD2-CE1 4.21Å; L125-Y191 HydrophobicContact CD2-CE2 3.98Å; L125-Y191 HydrophobicContact CD2-CG 3.77Å; L125-Y191 VanDerWaalsContact CD2-O 3.25Å; L125-Y191 WeakPolarHBondContact CD2-O 3.4Å; L125-Y191 HydrophobicContact CG-CD2 4.43Å; L125-Y191 HydrophobicContact CG-CE2 4.22Å; L125-Y191 WeakPolarHBondContact O-CD2 3.29Å; L125-Y191 WeakPolarHBondContact O-CE2 3.46Å; L125-I194 HydrophobicContact CD2-CB 3.91Å; L125-I194 HydrophobicContact CD2-CG2 3.86Å; L125-I194 HydrophobicContact CG-CG2 4.24Å; L125-A195 HydrophobicContact CD1-CB 4.36Å; L125-A195 HydrophobicContact CD2-CB 4.46Å
126G98.3Very high97.8Very high1 Ų116 Ų161%0.018%0.083CC..Hα-helixtrans-54.5-46.9172.300000112.3A122 V123 L124 A129 V130A122-G126 PolarHBondContact O-N 3.3Å; V123-G126 WeakPolarHBondContact O-CA 3.44Å; V123-G126 PolarHBondContact O-N 2.82Å; V123-G126 VanDerWaalsContact O-N 3.16Å; L124-G126 VanDerWaalsContact C-N 3.31Å; L124-G126 PolarHBondContact O-N 3.07Å; G126-A129 PolarHBondContact O-N 3.3Å; G126-V130 WeakPolarHBondContact O-CG2 3.38Å; G126-V130 PolarHBondContact O-N 3.49Å
127S98.3Very high97.7Very high0 Ų017.9 Ų17.90%09%0.09CC..Hα-helixtrans-65.3-39178.673.40000113.7V123 L124 L125 A129 V130 Q131 W175 H179V123-S127 PolarHBondContact O-N 2.92Å; L124-S127 PolarHBondContact O-N 3.35Å; L124-S127 VanDerWaalsContact O-N 3.13Å; L124-S127 PolarHBondContact O-OG 3.27Å; L125-S127 VanDerWaalsContact C-N 3.33Å; L125-S127 PolarHBondContact O-N 3.09Å; S127-A129 VanDerWaalsContact C-N 3.34Å; S127-V130 PolarHBondContact O-N 3.21Å; S127-Q131 PolarHBondContact O-N 2.97Å; S127-W175 VanDerWaalsContact CB-CB 3.48Å; S127-H179 PolarHBondContact OG-NE2 3.44Å
128Y98.6Very high97.5Very high4 Ų421 Ų212%0.01611%0.107CC..Hα-helixtrans-64.6-37.9172.1-77.2-66.6000112L124 L125 V130 Q131 A132 H179 M182 E190 I194L124-Y128 HydrophobicContact CD1-CD2 4.26Å; L124-Y128 HydrophobicContact CD1-CE2 3.73Å; L124-Y128 HydrophobicContact CD2-CE2 4.4Å; L124-Y128 HydrophobicContact CG-CD2 4.15Å; L124-Y128 HydrophobicContact CG-CE2 3.77Å; L124-Y128 VanDerWaalsContact O-CD2 3.28Å; L124-Y128 WeakPolarHBondContact O-CD2 3.44Å; L124-Y128 PolarHBondContact O-N 3.15Å; L124-Y128 VanDerWaalsContact O-N 3.12Å; L125-Y128 PolarHBondContact O-N 3Å; Y128-V130 VanDerWaalsContact C-N 3.33Å; Y128-V130 PolarHBondContact O-N 3.35Å; Y128-Q131 PolarHBondContact O-N 3.11Å; Y128-A132 WeakPolarHBondContact O-CB 3.39Å; Y128-A132 PolarHBondContact O-N 3.47Å; Y128-H179 AromaticContact CD1-CE1 3.77Å; Y128-H179 AromaticContact CD1-NE2 3.79Å; Y128-H179 AromaticContact CE1-CE1 3.27Å; Y128-H179 WeakPolarHBondContact CE1-CE1 3.47Å; Y128-H179 AromaticContact CE1-ND1 3.45Å; Y128-H179 WeakPolarHBondContact CE1-ND1 3.16Å; Y128-H179 AromaticContact CE1-NE2 3.78Å; Y128-H179 AromaticContact CE2-CE1 3.79Å; Y128-H179 AromaticContact CG-NE2 3.95Å; Y128-H179 AromaticContact CZ-CE1 3.28Å; Y128-H179 AromaticContact CZ-ND1 3.85Å; Y128-H179 AromaticContact CZ-NE2 3.94Å; Y128-M182 HydrophobicContact CD1-SD 4.08Å; Y128-M182 HydrophobicContact CE1-CE 3.95Å; Y128-M182 HydrophobicContact CE1-SD 3.83Å; Y128-E190 HydrophobicContact CD1-CB 4.01Å; Y128-E190 HydrophobicContact CE1-CB 3.67Å; Y128-E190 HydrophobicContact CE1-CG 4.36Å; Y128-I194 HydrophobicContact CD2-CD1 4.11Å; Y128-I194 HydrophobicContact CE2-CD1 3.52Å
129A98.4Very high97.2Very high9 Ų928.4 Ų28.47%0.07414%0.139CC..Hα-helixtrans-67.5-32175.600000112.9F103 K107 L125 G126 S127 K133 Y191F103-A129 HydrophobicContact CE2-CB 4.22Å; F103-A129 HydrophobicContact CZ-CB 4.02Å; K107-A129 HydrophobicContact CD-CB 3.78Å; L125-A129 WeakPolarHBondContact O-CB 3.39Å; L125-A129 PolarHBondContact O-N 3.38Å; G126-A129 PolarHBondContact O-N 3.3Å; S127-A129 VanDerWaalsContact C-N 3.34Å; A129-K133 WeakPolarHBondContact O-CB 3.37Å; A129-K133 PolarHBondContact O-N 2.82Å; A129-K133 VanDerWaalsContact O-N 3.1Å; A129-Y191 HydrophobicContact CB-CD2 4.23Å; A129-Y191 HydrophobicContact CB-CE2 4.07Å
130V98.1Very high97Very high1 Ų135.3 Ų35.31%0.00617%0.171CC..Hα-helixtrans-67.3-50.1171.2177.60000110.5G126 S127 Y128 A132 K133 F134 Y146 L147 L152 I172 H176G126-V130 WeakPolarHBondContact O-CG2 3.38Å; G126-V130 PolarHBondContact O-N 3.49Å; S127-V130 PolarHBondContact O-N 3.21Å; Y128-V130 VanDerWaalsContact C-N 3.33Å; Y128-V130 PolarHBondContact O-N 3.35Å; V130-A132 VanDerWaalsContact C-N 3.29Å; V130-A132 PolarHBondContact O-N 3.45Å; V130-K133 PolarHBondContact O-N 2.96Å; V130-K133 VanDerWaalsContact O-N 3.07Å; V130-F134 HydrophobicContact CG1-CD2 3.71Å; V130-F134 HydrophobicContact CG1-CE2 4.28Å; V130-F134 WeakPolarHBondContact O-CD2 3.41Å; V130-F134 PolarHBondContact O-N 3.03Å; V130-Y146 HydrophobicContact CG1-CE2 4.3Å; V130-L147 HydrophobicContact CG1-CD2 3.82Å; V130-L147 HydrophobicContact CG2-CD1 4.22Å; V130-L147 HydrophobicContact CG2-CD2 3.79Å; V130-L152 HydrophobicContact CG2-CD1 3.72Å; V130-L152 HydrophobicContact CG2-CD2 3.72Å; V130-L152 HydrophobicContact CG2-CG 4.37Å; V130-I172 HydrophobicContact CG2-CG2 3.87Å; V130-H176 HydrophobicContact CG1-CB 4.22Å; V130-H176 VanDerWaalsContact CG1-CE1 3.46Å; V130-H176 WeakPolarHBondContact CG1-CE1 3.49Å; V130-H176 VanDerWaalsContact CG1-ND1 3.31Å; V130-H176 WeakPolarHBondContact CG1-ND1 3.36Å
131Q98.1Very high96.8Very high0 Ų038.8 Ų38.80%019%0.194CC..Hα-helixtrans-57.3-41.7175.7-178.271.921.700111.7S127 Y128 K133 G135 D136 H176 H179 M182 A187S127-Q131 PolarHBondContact O-N 2.97Å; Y128-Q131 PolarHBondContact O-N 3.11Å; Q131-K133 VanDerWaalsContact C-N 3.34Å; Q131-K133 PolarHBondContact O-N 3.27Å; Q131-G135 VanDerWaalsContact O-CA 3.27Å; Q131-G135 WeakPolarHBondContact O-CA 3.39Å; Q131-G135 PolarHBondContact O-N 2.78Å; Q131-D136 PolarHBondContact NE2-OD1 2.89Å; Q131-H176 PolarHBondContact OE1-CD2 2.99Å; Q131-H176 PolarHBondContact OE1-NE2 3.49Å; Q131-H179 HydrophobicContact CB-CB 3.99Å; Q131-H179 HydrophobicContact CG-CB 3.76Å; Q131-H179 PolarHBondContact NE2-O 2.89Å; Q131-M182 HydrophobicContact CG-CB 4.22Å; Q131-M182 PolarHBondContact NE2-O 3.49Å; Q131-A187 HydrophobicContact CB-CB 4.06Å; Q131-A187 HydrophobicContact CG-CB 3.81Å
132A97.8Very high96.7Very high11 Ų1139.1 Ų39.19%0.09119%0.194CC..Hα-helixtrans-63.2-35.9176.400000113.1F103 Y128 V130 K184 A187 M188F103-A132 HydrophobicContact CE1-CB 4.31Å; F103-A132 HydrophobicContact CE2-CB 4.48Å; F103-A132 HydrophobicContact CZ-CB 3.91Å; Y128-A132 WeakPolarHBondContact O-CB 3.39Å; Y128-A132 PolarHBondContact O-N 3.47Å; V130-A132 VanDerWaalsContact C-N 3.29Å; V130-A132 PolarHBondContact O-N 3.45Å; A132-K184 WeakPolarHBondContact O-CD 3.32Å; A132-K184 WeakPolarHBondContact O-CG 3.26Å; A132-A187 HydrophobicContact CB-CB 4.12Å; A132-M188 HydrophobicContact CB-CG 3.63Å
133K96.3Very high96.4Very high108 Ų10845 Ų4547%0.4722%0.219SC..Hα-helixtrans-79.7-57.3178.8-173.5174.9-174-179.20111.9A129 V130 Q131 E150 K184A129-K133 WeakPolarHBondContact O-CB 3.37Å; A129-K133 PolarHBondContact O-N 2.82Å; A129-K133 VanDerWaalsContact O-N 3.1Å; V130-K133 PolarHBondContact O-N 2.96Å; V130-K133 VanDerWaalsContact O-N 3.07Å; Q131-K133 VanDerWaalsContact C-N 3.34Å; Q131-K133 PolarHBondContact O-N 3.27Å; K133-E150 WeakPolarHBondContact CD-OE2 3.16Å; K133-E150 IonicContact NZ-OE1 2.75Å; K133-E150 PolarHBondContact NZ-OE1 3.31Å; K133-E150 IonicContact NZ-OE2 2.76Å; K133-E150 PolarHBondContact NZ-OE2 3.13Å; K133-K184 PolarHBondContact O-NZ 3.46Å
134F96.2Very high96Very high65 Ų6550.5 Ų50.529%0.28526%0.257SS..Hα-helixtrans-88.1-35.2-169.6-63.9-86.1000112.5V130 L147 E150 K184V130-F134 HydrophobicContact CG1-CD2 3.71Å; V130-F134 HydrophobicContact CG1-CE2 4.28Å; V130-F134 WeakPolarHBondContact O-CD2 3.41Å; V130-F134 PolarHBondContact O-N 3.03Å; F134-L147 HydrophobicContact CD2-CD2 4.47Å; F134-L147 HydrophobicContact CE2-CD2 3.83Å; F134-L147 HydrophobicContact CZ-CD2 4.33Å; F134-E150 HydrophobicContact CE2-CG 4.39Å; F134-E150 HydrophobicContact CZ-CG 4.43Å; F134-K184 PolarHBondContact O-NZ 3.22Å
135G95.9Very high95.7Very high10 Ų1052.2 Ų52.210%0.10328%0.275CS..  trans81.9-174.2-163.300000110.8Q131 Y137 H176Q131-G135 VanDerWaalsContact O-CA 3.27Å; Q131-G135 WeakPolarHBondContact O-CA 3.39Å; Q131-G135 PolarHBondContact O-N 2.78Å; G135-Y137 PolarHBondContact O-N 3.48Å; G135-H176 PolarHBondContact O-NE2 2.92Å
136D95.6Very high95.5Very high64 Ų6454 Ų5434%0.34228%0.282SS..SBendtrans-42.6131.8-171.6-80.413.3000115.5Q131 N138 R180 G181Q131-D136 PolarHBondContact NE2-OD1 2.89Å; D136-N138 PolarHBondContact O-N 2.71Å; D136-N138 VanDerWaalsContact O-N 3.15Å; D136-R180 HydrophobicContact CB-CG 4.32Å; D136-R180 VanDerWaalsContact OD2-CG 3.26Å; D136-R180 WeakPolarHBondContact OD2-CG 3.23Å; D136-G181 PolarHBondContact OD1-N 3.24Å; D136-G181 PolarHBondContact OD2-N 3.34Å
137Y96.4Very high95.3Very high44 Ų4454 Ų5417%0.17328%0.282CS..  trans-61.8114.9173.8179.4-108.8000112.6G135 K139 H142 Y146 Q173 H176 A177G135-Y137 PolarHBondContact O-N 3.48Å; Y137-K139 HydrophobicContact CE1-CB 4.38Å; Y137-H142 HydrophobicContact CD2-CB 3.84Å; Y137-H142 AromaticContact CD2-ND1 3.53Å; Y137-H142 HydrophobicContact CE2-CB 3.57Å; Y137-Y146 HydrophobicContact CE2-CE1 4.49Å; Y137-Q173 HydrophobicContact CD2-CG 4.1Å; Y137-Q173 HydrophobicContact CE2-CG 3.52Å; Y137-Q173 PolarHBondContact OH-OE1 3.45Å; Y137-Q173 VanDerWaalsContact OH-OE1 3.09Å; Y137-H176 AromaticContact CD2-ND1 3.8Å; Y137-A177 HydrophobicContact CD1-CB 3.76Å; Y137-A177 HydrophobicContact CE1-CB 4.49Å; Y137-A177 HydrophobicContact CG-CB 4.29Å
138N93.7Very high95Very high66 Ų6656.4 Ų56.435%0.35330%0.299SS..  trans-116.3118.1167.1-177.5-1000111D136 E140 V141 H142D136-N138 PolarHBondContact O-N 2.71Å; D136-N138 VanDerWaalsContact O-N 3.15Å; N138-E140 PolarHBondContact O-N 2.97Å; N138-E140 VanDerWaalsContact O-N 3.14Å; N138-E140 WeakPolarHBondContact OD1-CB 3.46Å; N138-E140 PolarHBondContact OD1-N 2.81Å; N138-V141 HydrophobicContact CB-CG2 4.44Å; N138-V141 PolarHBondContact O-N 3.41Å; N138-H142 PolarHBondContact N-ND1 2.95Å; N138-H142 WeakPolarHBondContact O-CB 3.48Å; N138-H142 PolarHBondContact O-N 2.78Å
139K93.4Very high94.6Very high160 Ų16060.7 Ų60.770%0.69633%0.329SS*.THydrogen-bonded Turntrans-58.5-20.8176.1-173.4178.4179.4-179.10114.1Y137 K143Y137-K139 HydrophobicContact CE1-CB 4.38Å; K139-K143 PolarHBondContact O-NZ 3.36Å
140E93.1Very high94.4Very high149 Ų14962 Ų6270%0.69633%0.334SS*.THydrogen-bonded Turntrans-75.7-34.2175.8-64.6177.4160.200112.3N138 K143N138-E140 PolarHBondContact O-N 2.97Å; N138-E140 VanDerWaalsContact O-N 3.14Å; N138-E140 WeakPolarHBondContact OD1-CB 3.46Å; N138-E140 PolarHBondContact OD1-N 2.81Å; E140-K143 WeakPolarHBondContact O-CE 3.47Å; E140-K143 PolarHBondContact O-NZ 2.91Å
141V93.1Very high94.1Very high102 Ų10268.7 Ų68.762%0.61836%0.359SS*.THydrogen-bonded Turntrans-97.6-49.5-177.2-179.10000111.1N138 K143N138-V141 HydrophobicContact CB-CG2 4.44Å; N138-V141 PolarHBondContact O-N 3.41Å; V141-K143 PolarHBondContact O-N 2.84Å
142H95.1Very high93.8Very high23 Ų2369.8 Ų69.811%0.10637%0.365CS..  trans-84.392.1-179.2-56.1145.8000109.9Y137 N138 Y146Y137-H142 HydrophobicContact CD2-CB 3.84Å; Y137-H142 AromaticContact CD2-ND1 3.53Å; Y137-H142 HydrophobicContact CE2-CB 3.57Å; N138-H142 PolarHBondContact N-ND1 2.95Å; N138-H142 WeakPolarHBondContact O-CB 3.48Å; N138-H142 PolarHBondContact O-N 2.78Å; H142-Y146 HydrophobicContact CB-CD1 4.09Å; H142-Y146 HydrophobicContact CB-CD2 3.81Å; H142-Y146 HydrophobicContact CB-CE1 4.18Å; H142-Y146 HydrophobicContact CB-CE2 3.89Å; H142-Y146 HydrophobicContact CB-CG 3.91Å; H142-Y146 AromaticContact CD2-CD2 3.72Å; H142-Y146 AromaticContact CG-CD2 3.77Å; H142-Y146 AromaticContact CG-CE2 3.75Å
143K92.5Very high93.7Very high125 Ų12569.7 Ų69.754%0.54336%0.362SS..  trans-83164.9170.7-54.4-53.2179-166.20110.8K139 E140 V141 G145 Y146K139-K143 PolarHBondContact O-NZ 3.36Å; E140-K143 WeakPolarHBondContact O-CE 3.47Å; E140-K143 PolarHBondContact O-NZ 2.91Å; V141-K143 PolarHBondContact O-N 2.84Å; K143-G145 PolarHBondContact O-N 3.34Å; K143-Y146 WeakPolarHBondContact O-CB 3.43Å; K143-Y146 WeakPolarHBondContact O-CD1 3.45Å; K143-Y146 PolarHBondContact O-N 2.76Å; K143-Y146 VanDerWaalsContact O-N 3.13Å
144S90.7Very high93.7Very high116 Ų11664.6 Ų64.681%0.81134%0.34SS*.THydrogen-bonded Turntrans-52139171.8-175.60000110.7
145G90.9Very high93.7Very high36 Ų3666.2 Ų66.237%0.37135%0.349SS..THydrogen-bonded Turntrans84.1-0.2-173.400000116.2K143 L147 S148K143-G145 PolarHBondContact O-N 3.34Å; G145-L147 PolarHBondContact O-N 3.47Å; G145-L147 VanDerWaalsContact O-N 3.07Å; G145-S148 WeakPolarHBondContact CA-OG 3.07Å; G145-S148 WeakPolarHBondContact O-CB 3.22Å; G145-S148 PolarHBondContact O-N 2.83Å; G145-S148 PolarHBondContact O-OG 2.86Å
146Y94.6Very high93.8Very high39 Ų3966.9 Ų66.915%0.15335%0.348CS..THydrogen-bonded Turntrans-63.9-10.7176.682.8-67.8000114.6V130 Y137 H142 K143 Q173 H176V130-Y146 HydrophobicContact CG1-CE2 4.3Å; Y137-Y146 HydrophobicContact CE2-CE1 4.49Å; H142-Y146 HydrophobicContact CB-CD1 4.09Å; H142-Y146 HydrophobicContact CB-CD2 3.81Å; H142-Y146 HydrophobicContact CB-CE1 4.18Å; H142-Y146 HydrophobicContact CB-CE2 3.89Å; H142-Y146 HydrophobicContact CB-CG 3.91Å; H142-Y146 AromaticContact CD2-CD2 3.72Å; H142-Y146 AromaticContact CG-CD2 3.77Å; H142-Y146 AromaticContact CG-CE2 3.75Å; K143-Y146 WeakPolarHBondContact O-CB 3.43Å; K143-Y146 WeakPolarHBondContact O-CD1 3.45Å; K143-Y146 PolarHBondContact O-N 2.76Å; K143-Y146 VanDerWaalsContact O-N 3.13Å; Y146-Q173 HydrophobicContact CE1-CB 4.23Å; Y146-Q173 HydrophobicContact CE1-CG 3.91Å; Y146-H176 AromaticContact CZ-ND1 3.9Å; Y146-H176 PolarHBondContact OH-ND1 3.15Å
147L94.9Very high93.9Very high1 Ų163.9 Ų63.91%0.00533%0.332CS..THydrogen-bonded Turntrans-1062175.7-59.5178.5000112.8V130 F134 G145 S149 E150 L152 E169 I172V130-L147 HydrophobicContact CG1-CD2 3.82Å; V130-L147 HydrophobicContact CG2-CD1 4.22Å; V130-L147 HydrophobicContact CG2-CD2 3.79Å; F134-L147 HydrophobicContact CD2-CD2 4.47Å; F134-L147 HydrophobicContact CE2-CD2 3.83Å; F134-L147 HydrophobicContact CZ-CD2 4.33Å; G145-L147 PolarHBondContact O-N 3.47Å; G145-L147 VanDerWaalsContact O-N 3.07Å; L147-S149 PolarHBondContact O-N 2.9Å; L147-S149 VanDerWaalsContact O-N 3.16Å; L147-E150 HydrophobicContact CD2-CG 4.35Å; L147-E150 WeakPolarHBondContact O-CB 3.36Å; L147-E150 PolarHBondContact O-N 2.86Å; L147-L152 HydrophobicContact CB-CD1 4.06Å; L147-L152 HydrophobicContact CD1-CD1 3.86Å; L147-L152 HydrophobicContact CD2-CD1 4.18Å; L147-L152 HydrophobicContact CG-CD1 4.24Å; L147-E169 VanDerWaalsContact C-CD 3.49Å; L147-E169 VanDerWaalsContact C-OE2 3.27Å; L147-E169 WeakPolarHBondContact CA-OE2 3.5Å; L147-E169 HydrophobicContact CB-CB 4.29Å; L147-E169 HydrophobicContact CB-CG 3.79Å; L147-E169 WeakPolarHBondContact CB-OE2 3.48Å; L147-E169 HydrophobicContact CD1-CB 4.46Å; L147-E169 PolarHBondContact N-OE2 3.16Å; L147-I172 HydrophobicContact CD1-CB 4.47Å; L147-I172 HydrophobicContact CD1-CG2 4.25Å
148S91.5Very high93.8Very high51 Ų5164.3 Ų64.336%0.35734%0.336SS..THydrogen-bonded Turntrans-72.6-7.1-175.3-56.60000115.1G145 R165 E169G145-S148 WeakPolarHBondContact CA-OG 3.07Å; G145-S148 WeakPolarHBondContact O-CB 3.22Å; G145-S148 PolarHBondContact O-N 2.83Å; G145-S148 PolarHBondContact O-OG 2.86Å; S148-R165 VanDerWaalsContact C-NH2 3.26Å; S148-R165 PolarHBondContact O-NH1 3.02Å; S148-R165 VanDerWaalsContact O-NH1 3.13Å; S148-R165 PolarHBondContact O-NH2 3.09Å; S148-E169 WeakPolarHBondContact CA-OE1 3.37Å; S148-E169 WeakPolarHBondContact CB-OE1 3.35Å; S148-E169 PolarHBondContact N-OE1 3Å; S148-E169 PolarHBondContact N-OE2 2.84Å; S148-E169 VanDerWaalsContact N-OE2 3.11Å; S148-E169 VanDerWaalsContact OG-CD 3.31Å; S148-E169 PolarHBondContact OG-OE1 2.87Å; S148-E169 PolarHBondContact OG-OE2 2.69Å
149S91.1Very high93.9Very high94 Ų9465 Ų6566%0.65734%0.34SS*.THydrogen-bonded Turntrans-84.7-17.2164.153.40000113.7L147L147-S149 PolarHBondContact O-N 2.9Å; L147-S149 VanDerWaalsContact O-N 3.16Å
150E92.8Very high94Very high36 Ų3657.6 Ų57.617%0.16831%0.308CS..  trans-95.5145.6-164.5-54.3-54.4120.800113.7K133 F134 L147 L152 R165K133-E150 WeakPolarHBondContact CD-OE2 3.16Å; K133-E150 IonicContact NZ-OE1 2.75Å; K133-E150 PolarHBondContact NZ-OE1 3.31Å; K133-E150 IonicContact NZ-OE2 2.76Å; K133-E150 PolarHBondContact NZ-OE2 3.13Å; F134-E150 HydrophobicContact CE2-CG 4.39Å; F134-E150 HydrophobicContact CZ-CG 4.43Å; L147-E150 HydrophobicContact CD2-CG 4.35Å; L147-E150 WeakPolarHBondContact O-CB 3.36Å; L147-E150 PolarHBondContact O-N 2.86Å; E150-L152 HydrophobicContact CB-CD1 4.04Å; E150-L152 HydrophobicContact CB-CD2 3.7Å; E150-L152 HydrophobicContact CB-CG 3.63Å; E150-L152 HydrophobicContact CG-CD2 4.36Å; E150-R165 PolarHBondContact O-NH2 3.31Å
151R93.2Very high94.2Very high142 Ų14250.8 Ų50.854%0.53628%0.276SS..  trans-102.9105.2163.2-176.3179.8177.7164.50.9107.7L111L111-R151 HydrophobicContact CD1-CG 4.34Å; L111-R151 WeakPolarHBondContact CD1-O 3.15Å; L111-R151 HydrophobicContact CD2-CG 4.33Å; L111-R151 PolarHBondContact O-NE 3.5Å; L111-R151 PolarHBondContact O-NH2 3.47Å
152L90.1Very high94.3Very high24 Ų2452.5 Ų52.513%0.12628%0.275CS..  trans-110.4-22.7-169.6-61.3175000114.1L111 V130 L147 E150 I172L111-L152 VanDerWaalsContact CD2-C 3.43Å; V130-L152 HydrophobicContact CG2-CD1 3.72Å; V130-L152 HydrophobicContact CG2-CD2 3.72Å; V130-L152 HydrophobicContact CG2-CG 4.37Å; L147-L152 HydrophobicContact CB-CD1 4.06Å; L147-L152 HydrophobicContact CD1-CD1 3.86Å; L147-L152 HydrophobicContact CD2-CD1 4.18Å; L147-L152 HydrophobicContact CG-CD1 4.24Å; E150-L152 HydrophobicContact CB-CD1 4.04Å; E150-L152 HydrophobicContact CB-CD2 3.7Å; E150-L152 HydrophobicContact CB-CG 3.63Å; E150-L152 HydrophobicContact CG-CD2 4.36Å; L152-I172 HydrophobicContact CB-CD1 3.83Å; L152-I172 HydrophobicContact CD1-CD1 3.99Å; L152-I172 HydrophobicContact CD1-CG2 4.13Å
153I96.1Very high94.3Very high8 Ų852.8 Ų52.84%0.04128%0.278CS..SBendtrans-133.8159.3177.252175000110.9A122 V123 V157 M158 W168 I172A122-I153 HydrophobicContact CB-CG2 4.2Å; A122-I153 WeakPolarHBondContact O-CG2 3.45Å; V123-I153 HydrophobicContact CG2-CG2 4.41Å; I153-V157 HydrophobicContact CD1-CG1 4.29Å; I153-M158 HydrophobicContact CD1-CG 3.53Å; I153-M158 HydrophobicContact CD1-SD 4.42Å; I153-M158 HydrophobicContact CG1-CG 3.73Å; I153-M158 HydrophobicContact CG1-SD 4.2Å; I153-W168 HydrophobicContact CD1-CB 4.45Å; I153-W168 HydrophobicContact CD1-CD2 3.46Å; I153-W168 VanDerWaalsContact CD1-CD2 3.46Å; I153-W168 HydrophobicContact CD1-CE3 3.56Å; I153-W168 HydrophobicContact CD1-CG 3.91Å; I153-W168 HydrophobicContact CD1-CH2 4.14Å; I153-W168 HydrophobicContact CD1-CZ2 4.04Å; I153-W168 HydrophobicContact CD1-CZ3 3.92Å; I153-I172 HydrophobicContact CG2-CD1 4.33Å
154P97.4Very high94.4Very high1 Ų150.2 Ų50.21%0.00627%0.272CS..  trans-68.4151.8177.1-12.626.8000111.8I110 D113 A122 R156 V157 M158I110-P154 HydrophobicContact CG2-CG 4.21Å; I110-P154 WeakPolarHBondContact O-CG 3.46Å; D113-P154 VanDerWaalsContact OD2-CB 3.22Å; D113-P154 WeakPolarHBondContact OD2-CB 3.3Å; A122-P154 HydrophobicContact CB-CG 4.44Å; P154-R156 VanDerWaalsContact C-N 3.31Å; P154-R156 PolarHBondContact O-N 2.88Å; P154-V157 HydrophobicContact CB-CG2 4.31Å; P154-V157 HydrophobicContact CG-CG2 4.05Å; P154-V157 WeakPolarHBondContact O-CB 3.47Å; P154-V157 PolarHBondContact O-N 3.36Å; P154-M158 PolarHBondContact O-N 3.37Å
155Q96.2Very high94.5Very high99 Ų9949.9 Ų49.946%0.46325%0.253SS..Hα-helixtrans-61.9-39.9-176.7-173.162.946.600111.4V157 M158 D159Q155-V157 PolarHBondContact O-N 3.03Å; Q155-V157 VanDerWaalsContact O-N 3.16Å; Q155-M158 WeakPolarHBondContact O-CB 3.24Å; Q155-M158 PolarHBondContact O-N 3.06Å; Q155-D159 PolarHBondContact NE2-OD1 3.16Å; Q155-D159 VanDerWaalsContact O-CG 3.27Å; Q155-D159 PolarHBondContact O-N 3.36Å
156R97.2Very high94.6Very high25 Ų2552.8 Ų52.89%0.09426%0.26CS..Hα-helixtrans-52.5-34.7172.6171.4-176.353.578.812.9113.4D113 Y116 C117 P154 Q160 T548 D551D113-R156 IonicContact OD1-CZ 3.81Å; D113-R156 VanDerWaalsContact OD1-CZ 3.22Å; D113-R156 IonicContact OD1-NE 3.81Å; D113-R156 PolarHBondContact OD1-NE 2.71Å; D113-R156 IonicContact OD1-NH2 2.74Å; D113-R156 PolarHBondContact OD1-NH2 2.71Å; Y116-R156 VanDerWaalsContact CE2-NH1 3.27Å; C117-R156 PolarHBondContact O-NH1 2.95Å; C117-R156 VanDerWaalsContact O-NH1 3.07Å; C117-R156 PolarHBondContact O-NH2 2.91Å; P154-R156 VanDerWaalsContact C-N 3.31Å; P154-R156 PolarHBondContact O-N 2.88Å; R156-Q160 WeakPolarHBondContact O-CB 3.48Å; R156-Q160 WeakPolarHBondContact O-CG 3.41Å; R156-Q160 PolarHBondContact O-N 3.44Å; R156-Q160 PolarHBondContact O-NE2 2.62Å; R156-T548 WeakPolarHBondContact CD-OG1 3.36Å; R156-T548 HydrophobicContact CG-CG2 3.78Å; R156-D551 IonicContact CZ-OD1 3.39Å; R156-D551 IonicContact NH1-OD1 3.51Å; R156-D551 PolarHBondContact NH1-OD1 2.66Å
157V97.4Very high94.6Very high0 Ų055 Ų550%027%0.272CS..Hα-helixtrans-75.8-38.8180176.90000110.7P119 A122 I153 P154 Q155 H161 W168P119-V157 HydrophobicContact CB-CG1 3.92Å; P119-V157 HydrophobicContact CG-CG1 4.46Å; A122-V157 HydrophobicContact CB-CG1 4.49Å; A122-V157 HydrophobicContact CB-CG2 4.08Å; I153-V157 HydrophobicContact CD1-CG1 4.29Å; P154-V157 HydrophobicContact CB-CG2 4.31Å; P154-V157 HydrophobicContact CG-CG2 4.05Å; P154-V157 WeakPolarHBondContact O-CB 3.47Å; P154-V157 PolarHBondContact O-N 3.36Å; Q155-V157 PolarHBondContact O-N 3.03Å; Q155-V157 VanDerWaalsContact O-N 3.16Å; V157-H161 PolarHBondContact O-ND1 2.94Å; V157-W168 HydrophobicContact CG1-CH2 3.84Å; V157-W168 HydrophobicContact CG1-CZ2 4.31Å; V157-W168 WeakPolarHBondContact O-CZ2 3.46Å
158M95.4Very high94.6Very high53 Ų5355.2 Ų55.226%0.26127%0.273SS..Hα-helixtrans-64.9-49.1173.4-60.7-172.177.300111.3I153 P154 Q155 Q160 H161I153-M158 HydrophobicContact CD1-CG 3.53Å; I153-M158 HydrophobicContact CD1-SD 4.42Å; I153-M158 HydrophobicContact CG1-CG 3.73Å; I153-M158 HydrophobicContact CG1-SD 4.2Å; P154-M158 PolarHBondContact O-N 3.37Å; Q155-M158 WeakPolarHBondContact O-CB 3.24Å; Q155-M158 PolarHBondContact O-N 3.06Å; M158-Q160 VanDerWaalsContact C-N 3.3Å; M158-Q160 PolarHBondContact O-N 3.21Å; M158-H161 PolarHBondContact O-N 3.08Å
159D95.4Very high94.8Very high82 Ų8253.5 Ų53.544%0.43926%0.259SS..Hα-helixtrans-60.7-38.8-175.2-66.9-19.4000112.2Q155 H161 K546Q155-D159 PolarHBondContact NE2-OD1 3.16Å; Q155-D159 VanDerWaalsContact O-CG 3.27Å; Q155-D159 PolarHBondContact O-N 3.36Å; D159-H161 VanDerWaalsContact C-N 3.32Å; D159-H161 PolarHBondContact O-N 3Å; D159-K546 WeakPolarHBondContact O-CD 3.41Å; D159-K546 WeakPolarHBondContact O-CE 3.3Å; D159-K546 PolarHBondContact O-NZ 3.09Å
160Q95.9Very high94.9Very high3 Ų353 Ų531%0.01425%0.249CC..THydrogen-bonded Turntrans-81.94.2-176.183179.7-89.700115.3R156 M158 D543 K546 D551R156-Q160 WeakPolarHBondContact O-CB 3.48Å; R156-Q160 WeakPolarHBondContact O-CG 3.41Å; R156-Q160 PolarHBondContact O-N 3.44Å; R156-Q160 PolarHBondContact O-NE2 2.62Å; M158-Q160 VanDerWaalsContact C-N 3.3Å; M158-Q160 PolarHBondContact O-N 3.21Å; Q160-D543 PolarHBondContact O-N 3.45Å; Q160-K546 HydrophobicContact CB-CB 3.95Å; Q160-D551 PolarHBondContact NE2-OD1 3.2Å; Q160-D551 VanDerWaalsContact NE2-OD1 3.14Å
161H96.8Very high95Very high7 Ų753.8 Ų53.83%0.03225%0.251CS..BIsolated β-bridgetrans-126.4147.7172.3-56.980.4000111.8V157 M158 D159 L163 W168 L538 A541 R542V157-H161 PolarHBondContact O-ND1 2.94Å; M158-H161 PolarHBondContact O-N 3.08Å; D159-H161 VanDerWaalsContact C-N 3.32Å; D159-H161 PolarHBondContact O-N 3Å; H161-L163 HydrophobicContact CB-CD1 4.24Å; H161-L163 HydrophobicContact CB-CG 4.21Å; H161-L163 PolarHBondContact O-N 3.2Å; H161-W168 HydrophobicContact CB-CH2 4.23Å; H161-W168 HydrophobicContact CB-CZ2 3.76Å; H161-W168 AromaticContact CG-CH2 3.95Å; H161-W168 AromaticContact CG-CZ2 3.93Å; H161-W168 AromaticContact ND1-CH2 3.71Å; H161-W168 AromaticContact ND1-CZ2 3.78Å; H161-L538 PolarHBondContact CD2-O 3.33Å; H161-A541 CarbonylContact C-O 3.59Å; H161-A541 VanDerWaalsContact CA-O 3.3Å; H161-A541 WeakPolarHBondContact CA-O 3.3Å; H161-A541 HydrophobicContact CB-CB 4.45Å; H161-R542 PolarHBondContact NE2-NE 3.16Å
162K94.7Very high95.2Very high137 Ų13747.1 Ų47.160%0.59623%0.226SC*.SBendtrans-84.654.2179.5-67.7161.9-178.9149.20110.5A541 D543K162-A541 PolarHBondContact N-O 3.24Å; K162-D543 VanDerWaalsContact CE-OD2 3.27Å; K162-D543 WeakPolarHBondContact CE-OD2 3.47Å; K162-D543 VanDerWaalsContact NZ-CG 3.29Å; K162-D543 IonicContact NZ-OD1 3.1Å; K162-D543 PolarHBondContact NZ-OD1 2.87Å; K162-D543 IonicContact NZ-OD2 2.75Å
163L95.1Very high95.5Very high30 Ų3048.2 Ų48.216%0.15723%0.23CC..  trans-121.5138.6-177.9-63.6176.6000110.9H161 Q167 W168 L538 A541H161-L163 HydrophobicContact CB-CD1 4.24Å; H161-L163 HydrophobicContact CB-CG 4.21Å; H161-L163 PolarHBondContact O-N 3.2Å; L163-Q167 HydrophobicContact CB-CB 4.29Å; L163-Q167 HydrophobicContact CD2-CB 4.27Å; L163-W168 HydrophobicContact CB-CD2 4.42Å; L163-W168 HydrophobicContact CD1-CD2 4.04Å; L163-W168 HydrophobicContact CD1-CE3 4.1Å; L163-W168 HydrophobicContact CD1-CH2 4Å; L163-W168 HydrophobicContact CD1-CZ2 3.92Å; L163-W168 HydrophobicContact CD1-CZ3 4.07Å; L163-L538 HydrophobicContact CD1-CD2 4.29Å; L163-A541 HydrophobicContact CD1-CB 4.23Å; L163-A541 HydrophobicContact CD2-CB 3.77Å; L163-A541 HydrophobicContact CG-CB 3.82Å
164T94.3Very high95.5Very high70 Ų7051.7 Ų51.743%0.42925%0.252SS..  trans-72.4167.7170.471.20000111.1D166 Q167 W168T164-D166 VanDerWaalsContact C-N 3.3Å; T164-D166 PolarHBondContact O-N 2.82Å; T164-D166 PolarHBondContact OG1-N 2.84Å; T164-Q167 PolarHBondContact O-N 2.8Å; T164-Q167 WeakPolarHBondContact OG1-CG 3.49Å; T164-Q167 PolarHBondContact OG1-N 2.9Å; T164-W168 PolarHBondContact O-N 2.99Å; T164-W168 VanDerWaalsContact O-N 3.15Å
165R92.6Very high95.5Very high109 Ų10952.7 Ų52.741%0.41126%0.255SS..Hα-helixtrans-56.1-47.8172.2-175-178.8-176.614617.3111.1S148 E150 Q167 W168 E169S148-R165 VanDerWaalsContact C-NH2 3.26Å; S148-R165 PolarHBondContact O-NH1 3.02Å; S148-R165 VanDerWaalsContact O-NH1 3.13Å; S148-R165 PolarHBondContact O-NH2 3.09Å; E150-R165 PolarHBondContact O-NH2 3.31Å; R165-Q167 VanDerWaalsContact C-N 3.29Å; R165-Q167 PolarHBondContact O-N 3.36Å; R165-W168 WeakPolarHBondContact O-CA 3.27Å; R165-W168 WeakPolarHBondContact O-CB 3.47Å; R165-W168 PolarHBondContact O-N 3.4Å; R165-E169 WeakPolarHBondContact CD-OE1 3.24Å; R165-E169 HydrophobicContact CG-CG 4.48Å; R165-E169 WeakPolarHBondContact CG-OE1 3.26Å; R165-E169 IonicContact CZ-OE1 2.77Å; R165-E169 IonicContact NE-OE1 2.59Å; R165-E169 PolarHBondContact NE-OE1 2.91Å; R165-E169 PolarHBondContact O-N 3.22Å
166D93.1Very high95.5Very high97 Ų9748 Ų4852%0.51923%0.233SC..Hα-helixtrans-60.4-40.8-177.4-34.8-32.9000110.9T164 W168 E169 D170T164-D166 VanDerWaalsContact C-N 3.3Å; T164-D166 PolarHBondContact O-N 2.82Å; T164-D166 PolarHBondContact OG1-N 2.84Å; D166-W168 VanDerWaalsContact C-N 3.31Å; D166-W168 PolarHBondContact O-N 2.9Å; D166-E169 PolarHBondContact O-N 2.89Å; D166-E169 VanDerWaalsContact O-N 3.12Å; D166-D170 PolarHBondContact O-N 3.05Å
167Q94.8Very high95.5Very high85 Ų8548.6 Ų48.640%0.39724%0.244SC..Hα-helixtrans-66.1-28.4174.6-71.3174.2-32.300113.6L163 T164 R165 R171L163-Q167 HydrophobicContact CB-CB 4.29Å; L163-Q167 HydrophobicContact CD2-CB 4.27Å; T164-Q167 PolarHBondContact O-N 2.8Å; T164-Q167 WeakPolarHBondContact OG1-CG 3.49Å; T164-Q167 PolarHBondContact OG1-N 2.9Å; R165-Q167 VanDerWaalsContact C-N 3.29Å; R165-Q167 PolarHBondContact O-N 3.36Å; Q167-R171 VanDerWaalsContact O-CG 3.29Å; Q167-R171 WeakPolarHBondContact O-CG 3.42Å; Q167-R171 PolarHBondContact O-N 3.28Å
168W95.8Very high95.4Very high6 Ų653.4 Ų53.42%0.02327%0.266CS..Hα-helixtrans-73.2-40.1169.1-74.7115.7000111.7V123 I153 V157 H161 L163 T164 R165 D166 R171 I172 L538V123-W168 HydrophobicContact CG2-CE3 4.15Å; V123-W168 HydrophobicContact CG2-CZ3 3.55Å; I153-W168 HydrophobicContact CD1-CB 4.45Å; I153-W168 HydrophobicContact CD1-CD2 3.46Å; I153-W168 VanDerWaalsContact CD1-CD2 3.46Å; I153-W168 HydrophobicContact CD1-CE3 3.56Å; I153-W168 HydrophobicContact CD1-CG 3.91Å; I153-W168 HydrophobicContact CD1-CH2 4.14Å; I153-W168 HydrophobicContact CD1-CZ2 4.04Å; I153-W168 HydrophobicContact CD1-CZ3 3.92Å; V157-W168 HydrophobicContact CG1-CH2 3.84Å; V157-W168 HydrophobicContact CG1-CZ2 4.31Å; V157-W168 WeakPolarHBondContact O-CZ2 3.46Å; H161-W168 HydrophobicContact CB-CH2 4.23Å; H161-W168 HydrophobicContact CB-CZ2 3.76Å; H161-W168 AromaticContact CG-CH2 3.95Å; H161-W168 AromaticContact CG-CZ2 3.93Å; H161-W168 AromaticContact ND1-CH2 3.71Å; H161-W168 AromaticContact ND1-CZ2 3.78Å; L163-W168 HydrophobicContact CB-CD2 4.42Å; L163-W168 HydrophobicContact CD1-CD2 4.04Å; L163-W168 HydrophobicContact CD1-CE3 4.1Å; L163-W168 HydrophobicContact CD1-CH2 4Å; L163-W168 HydrophobicContact CD1-CZ2 3.92Å; L163-W168 HydrophobicContact CD1-CZ3 4.07Å; T164-W168 PolarHBondContact O-N 2.99Å; T164-W168 VanDerWaalsContact O-N 3.15Å; R165-W168 WeakPolarHBondContact O-CA 3.27Å; R165-W168 WeakPolarHBondContact O-CB 3.47Å; R165-W168 PolarHBondContact O-N 3.4Å; D166-W168 VanDerWaalsContact C-N 3.31Å; D166-W168 PolarHBondContact O-N 2.9Å; W168-R171 PolarHBondContact O-N 3.32Å; W168-I172 WeakPolarHBondContact O-CB 3.23Å; W168-I172 VanDerWaalsContact O-CG1 3.28Å; W168-I172 WeakPolarHBondContact O-CG1 3.41Å; W168-I172 PolarHBondContact O-N 3.34Å; W168-L538 HydrophobicContact CH2-CD2 3.85Å; W168-L538 HydrophobicContact CZ3-CD2 3.6Å
169E94.8Very high95.5Very high15 Ų1550.9 Ų50.97%0.0725%0.254CS..Hα-helixtrans-64.4-43.7176.5-67.7-173.6-151.400111.6L147 S148 R165 D166 I172 Q173L147-E169 VanDerWaalsContact C-CD 3.49Å; L147-E169 VanDerWaalsContact C-OE2 3.27Å; L147-E169 WeakPolarHBondContact CA-OE2 3.5Å; L147-E169 HydrophobicContact CB-CB 4.29Å; L147-E169 HydrophobicContact CB-CG 3.79Å; L147-E169 WeakPolarHBondContact CB-OE2 3.48Å; L147-E169 HydrophobicContact CD1-CB 4.46Å; L147-E169 PolarHBondContact N-OE2 3.16Å; S148-E169 WeakPolarHBondContact CA-OE1 3.37Å; S148-E169 WeakPolarHBondContact CB-OE1 3.35Å; S148-E169 PolarHBondContact N-OE1 3Å; S148-E169 PolarHBondContact N-OE2 2.84Å; S148-E169 VanDerWaalsContact N-OE2 3.11Å; S148-E169 VanDerWaalsContact OG-CD 3.31Å; S148-E169 PolarHBondContact OG-OE1 2.87Å; S148-E169 PolarHBondContact OG-OE2 2.69Å; R165-E169 WeakPolarHBondContact CD-OE1 3.24Å; R165-E169 HydrophobicContact CG-CG 4.48Å; R165-E169 WeakPolarHBondContact CG-OE1 3.26Å; R165-E169 IonicContact CZ-OE1 2.77Å; R165-E169 IonicContact NE-OE1 2.59Å; R165-E169 PolarHBondContact NE-OE1 2.91Å; R165-E169 PolarHBondContact O-N 3.22Å; D166-E169 PolarHBondContact O-N 2.89Å; D166-E169 VanDerWaalsContact O-N 3.12Å; E169-I172 PolarHBondContact O-N 2.96Å; E169-Q173 WeakPolarHBondContact O-CB 3.46Å; E169-Q173 PolarHBondContact O-N 2.85Å
170D93.6Very high95.4Very high84 Ų8456.2 Ų56.245%0.44927%0.268SS..Hα-helixtrans-58.7-48.9174.8-75.2-23.4000111.6D166 I172 Q173 V174D166-D170 PolarHBondContact O-N 3.05Å; D170-I172 PolarHBondContact O-N 3.03Å; D170-Q173 WeakPolarHBondContact O-CB 3.24Å; D170-Q173 PolarHBondContact O-N 2.84Å; D170-V174 PolarHBondContact O-N 3.11Å
171R95.1Very high95.2Very high53 Ų5357.5 Ų57.520%0.228%0.282CS..Hα-helixtrans-61.1-45.8177.7-75.4177.5-177.1-86.213.3111.8Q167 W168 Q173 V174 W175 E537Q167-R171 VanDerWaalsContact O-CG 3.29Å; Q167-R171 WeakPolarHBondContact O-CG 3.42Å; Q167-R171 PolarHBondContact O-N 3.28Å; W168-R171 PolarHBondContact O-N 3.32Å; R171-Q173 VanDerWaalsContact C-N 3.29Å; R171-Q173 PolarHBondContact O-N 3.31Å; R171-V174 PolarHBondContact O-N 3.48Å; R171-W175 VanDerWaalsContact O-CD1 3.24Å; R171-W175 PolarHBondContact O-N 2.96Å; R171-E537 IonicContact NH1-OE2 3.62Å; R171-E537 PolarHBondContact NH1-OE2 3.44Å; R171-E537 PolarHBondContact NH2-O 3.41Å
172I96.9Very high95Very high2 Ų259 Ų591%0.0129%0.289CS..Hα-helixtrans-67.3-32.9177.6-64.2165.4000110.7V123 V130 L147 L152 I153 W168 E169 D170 W175 H176V123-I172 HydrophobicContact CG1-CG1 4.04Å; V130-I172 HydrophobicContact CG2-CG2 3.87Å; L147-I172 HydrophobicContact CD1-CB 4.47Å; L147-I172 HydrophobicContact CD1-CG2 4.25Å; L152-I172 HydrophobicContact CB-CD1 3.83Å; L152-I172 HydrophobicContact CD1-CD1 3.99Å; L152-I172 HydrophobicContact CD1-CG2 4.13Å; I153-I172 HydrophobicContact CG2-CD1 4.33Å; W168-I172 WeakPolarHBondContact O-CB 3.23Å; W168-I172 VanDerWaalsContact O-CG1 3.28Å; W168-I172 WeakPolarHBondContact O-CG1 3.41Å; W168-I172 PolarHBondContact O-N 3.34Å; E169-I172 PolarHBondContact O-N 2.96Å; D170-I172 PolarHBondContact O-N 3.03Å; I172-W175 PolarHBondContact O-N 3.29Å; I172-H176 VanDerWaalsContact O-CB 3.26Å; I172-H176 WeakPolarHBondContact O-CB 3.4Å; I172-H176 PolarHBondContact O-N 3.41Å
173Q96.7Very high94.9Very high47 Ų4754.9 Ų54.922%0.2227%0.273CS..Hα-helixtrans-67.2-33.8174.6-177.8-99.4-103.100112.7Y137 Y146 E169 D170 R171 A177Y137-Q173 HydrophobicContact CD2-CG 4.1Å; Y137-Q173 HydrophobicContact CE2-CG 3.52Å; Y137-Q173 PolarHBondContact OH-OE1 3.45Å; Y137-Q173 VanDerWaalsContact OH-OE1 3.09Å; Y146-Q173 HydrophobicContact CE1-CB 4.23Å; Y146-Q173 HydrophobicContact CE1-CG 3.91Å; E169-Q173 WeakPolarHBondContact O-CB 3.46Å; E169-Q173 PolarHBondContact O-N 2.85Å; D170-Q173 WeakPolarHBondContact O-CB 3.24Å; D170-Q173 PolarHBondContact O-N 2.84Å; R171-Q173 VanDerWaalsContact C-N 3.29Å; R171-Q173 PolarHBondContact O-N 3.31Å; Q173-A177 PolarHBondContact O-N 3.06Å
174V96.1Very high94.9Very high81 Ų8157.6 Ų57.649%0.49128%0.284SS..Hα-helixtrans-63.1-51.3171.7170.60000110D170 R171 H176 A177 E178D170-V174 PolarHBondContact O-N 3.11Å; R171-V174 PolarHBondContact O-N 3.48Å; V174-H176 VanDerWaalsContact C-N 3.29Å; V174-H176 PolarHBondContact O-N 2.83Å; V174-A177 WeakPolarHBondContact O-CB 3.45Å; V174-A177 PolarHBondContact O-N 3.11Å; V174-A177 VanDerWaalsContact O-N 3.14Å; V174-E178 PolarHBondContact O-N 2.8Å
175W96.8Very high94.8Very high21 Ų2156.3 Ų56.38%0.0827%0.274CS..Hα-helixtrans-68.7-25.1179-69107000113.8S127 R171 I172 E178 H179 Q530 T533 L534S127-W175 VanDerWaalsContact CB-CB 3.48Å; R171-W175 VanDerWaalsContact O-CD1 3.24Å; R171-W175 PolarHBondContact O-N 2.96Å; I172-W175 PolarHBondContact O-N 3.29Å; W175-E178 HydrophobicContact CE3-CB 4.41Å; W175-E178 HydrophobicContact CE3-CG 4.1Å; W175-E178 HydrophobicContact CZ3-CG 4.25Å; W175-E178 WeakPolarHBondContact O-CB 3.42Å; W175-E178 PolarHBondContact O-N 2.96Å; W175-H179 PolarHBondContact O-CD2 3.38Å; W175-H179 PolarHBondContact O-NE2 3.12Å; W175-Q530 HydrophobicContact CE3-CG 4.32Å; W175-Q530 HydrophobicContact CH2-CB 4.4Å; W175-Q530 HydrophobicContact CH2-CG 4.27Å; W175-Q530 HydrophobicContact CZ3-CB 4.15Å; W175-Q530 HydrophobicContact CZ3-CG 3.67Å; W175-T533 HydrophobicContact CH2-CG2 4.05Å; W175-T533 HydrophobicContact CZ2-CG2 3.83Å; W175-L534 HydrophobicContact CD2-CD1 4.42Å; W175-L534 HydrophobicContact CZ2-CD1 4.49Å; W175-L534 HydrophobicContact CZ2-CG 3.96Å; W175-L534 VanDerWaalsContact NE1-CD2 3.27Å
176H97.6Very high94.9Very high0 Ų053.5 Ų53.50%027%0.268CS..Hα-helixtrans-66-39.9170.3176.4-153.6000111.8V130 Q131 G135 Y137 Y146 I172 V174 E178 H179V130-H176 HydrophobicContact CG1-CB 4.22Å; V130-H176 VanDerWaalsContact CG1-CE1 3.46Å; V130-H176 WeakPolarHBondContact CG1-CE1 3.49Å; V130-H176 VanDerWaalsContact CG1-ND1 3.31Å; V130-H176 WeakPolarHBondContact CG1-ND1 3.36Å; Q131-H176 PolarHBondContact OE1-CD2 2.99Å; Q131-H176 PolarHBondContact OE1-NE2 3.49Å; G135-H176 PolarHBondContact O-NE2 2.92Å; Y137-H176 AromaticContact CD2-ND1 3.8Å; Y146-H176 AromaticContact CZ-ND1 3.9Å; Y146-H176 PolarHBondContact OH-ND1 3.15Å; I172-H176 VanDerWaalsContact O-CB 3.26Å; I172-H176 WeakPolarHBondContact O-CB 3.4Å; I172-H176 PolarHBondContact O-N 3.41Å; V174-H176 VanDerWaalsContact C-N 3.29Å; V174-H176 PolarHBondContact O-N 2.83Å; H176-E178 VanDerWaalsContact C-N 3.26Å; H176-E178 PolarHBondContact O-N 3.36Å; H176-H179 PolarHBondContact O-N 3.2Å; H176-H179 VanDerWaalsContact O-N 3.11Å
177A96.7Very high95.2Very high39 Ų3948.9 Ų48.932%0.32224%0.243SC..Hα-helixtrans-64.1-30.9177.800000112.9Y137 Q173 V174 H179 R180Y137-A177 HydrophobicContact CD1-CB 3.76Å; Y137-A177 HydrophobicContact CE1-CB 4.49Å; Y137-A177 HydrophobicContact CG-CB 4.29Å; Q173-A177 PolarHBondContact O-N 3.06Å; V174-A177 WeakPolarHBondContact O-CB 3.45Å; V174-A177 PolarHBondContact O-N 3.11Å; V174-A177 VanDerWaalsContact O-N 3.14Å; A177-H179 PolarHBondContact O-N 2.9Å; A177-R180 WeakPolarHBondContact O-CB 3.27Å; A177-R180 PolarHBondContact O-N 3.36Å
178E96Very high95.3Very high100 Ų10045.6 Ų45.647%0.46723%0.228SC..THydrogen-bonded Turntrans-64.5-22.8173.9-80.9-65.3121.700113.8V174 W175 H176 R180 R526V174-E178 PolarHBondContact O-N 2.8Å; W175-E178 HydrophobicContact CE3-CB 4.41Å; W175-E178 HydrophobicContact CE3-CG 4.1Å; W175-E178 HydrophobicContact CZ3-CG 4.25Å; W175-E178 WeakPolarHBondContact O-CB 3.42Å; W175-E178 PolarHBondContact O-N 2.96Å; H176-E178 VanDerWaalsContact C-N 3.26Å; H176-E178 PolarHBondContact O-N 3.36Å; E178-R180 VanDerWaalsContact C-N 3.29Å; E178-R180 PolarHBondContact O-N 2.85Å; E178-R526 PolarHBondContact O-NH2 2.8Å; E178-R526 IonicContact OE2-NH2 2.9Å; E178-R526 PolarHBondContact OE2-NH2 3.39Å; E178-R526 VanDerWaalsContact OE2-NH2 3.08Å
179H96.4Very high95.4Very high1 Ų146.5 Ų46.51%0.00523%0.233CC..THydrogen-bonded Turntrans-88.26179.8-57.6-43.9000113.7S127 Y128 Q131 W175 H176 A177 G181 M182S127-H179 PolarHBondContact OG-NE2 3.44Å; Y128-H179 AromaticContact CD1-CE1 3.77Å; Y128-H179 AromaticContact CD1-NE2 3.79Å; Y128-H179 AromaticContact CE1-CE1 3.27Å; Y128-H179 WeakPolarHBondContact CE1-CE1 3.47Å; Y128-H179 AromaticContact CE1-ND1 3.45Å; Y128-H179 WeakPolarHBondContact CE1-ND1 3.16Å; Y128-H179 AromaticContact CE1-NE2 3.78Å; Y128-H179 AromaticContact CE2-CE1 3.79Å; Y128-H179 AromaticContact CG-NE2 3.95Å; Y128-H179 AromaticContact CZ-CE1 3.28Å; Y128-H179 AromaticContact CZ-ND1 3.85Å; Y128-H179 AromaticContact CZ-NE2 3.94Å; Q131-H179 HydrophobicContact CB-CB 3.99Å; Q131-H179 HydrophobicContact CG-CB 3.76Å; Q131-H179 PolarHBondContact NE2-O 2.89Å; W175-H179 PolarHBondContact O-CD2 3.38Å; W175-H179 PolarHBondContact O-NE2 3.12Å; H176-H179 PolarHBondContact O-N 3.2Å; H176-H179 VanDerWaalsContact O-N 3.11Å; A177-H179 PolarHBondContact O-N 2.9Å; H179-G181 PolarHBondContact O-N 3.39Å; H179-M182 WeakPolarHBondContact O-CB 3.3Å; H179-M182 PolarHBondContact O-N 3.2Å
180R94.4Very high95.6Very high193 Ų19347.6 Ų47.673%0.72824%0.238SC*.THydrogen-bonded Turntrans-51.7131.3179.9-171.3-178.3-178.6-1741.1112.1D136 A177 E178D136-R180 HydrophobicContact CB-CG 4.32Å; D136-R180 VanDerWaalsContact OD2-CG 3.26Å; D136-R180 WeakPolarHBondContact OD2-CG 3.23Å; A177-R180 WeakPolarHBondContact O-CB 3.27Å; A177-R180 PolarHBondContact O-N 3.36Å; E178-R180 VanDerWaalsContact C-N 3.29Å; E178-R180 PolarHBondContact O-N 2.85Å
181G90.6Very high95.8Very high30 Ų3043.8 Ų43.831%0.30922%0.218SC..THydrogen-bonded Turntrans90.2-8.3-174.600000114D136 H179 R320D136-G181 PolarHBondContact OD1-N 3.24Å; D136-G181 PolarHBondContact OD2-N 3.34Å; H179-G181 PolarHBondContact O-N 3.39Å; G181-R320 PolarHBondContact O-NH1 3.45Å; G181-R320 PolarHBondContact O-NH2 3.13Å; G181-R320 VanDerWaalsContact O-NH2 3.16Å
182M93.8Very high96Very high38 Ų3841.3 Ų41.319%0.18721%0.208CC..  trans-79.9125.1179.5-169.8173.4-64.700111.7Y128 Q131 H179 N186 A187 E190Y128-M182 HydrophobicContact CD1-SD 4.08Å; Y128-M182 HydrophobicContact CE1-CE 3.95Å; Y128-M182 HydrophobicContact CE1-SD 3.83Å; Q131-M182 HydrophobicContact CG-CB 4.22Å; Q131-M182 PolarHBondContact NE2-O 3.49Å; H179-M182 WeakPolarHBondContact O-CB 3.3Å; H179-M182 PolarHBondContact O-N 3.2Å; M182-N186 HydrophobicContact CG-CB 3.94Å; M182-A187 HydrophobicContact CG-CB 4.15Å; M182-A187 VanDerWaalsContact SD-CA 3.59Å; M182-A187 HydrophobicContact SD-CB 3.83Å; M182-E190 HydrophobicContact CE-CG 4.45Å; M182-E190 HydrophobicContact SD-CG 4.34Å
183L92.1Very high96.1Very high51 Ų5142.3 Ų42.327%0.26721%0.212SC..  trans-61147.2172.4-65.7174.8000111D185 N186 A187L183-D185 PolarHBondContact O-N 3.48Å; L183-N186 HydrophobicContact CB-CB 4.33Å; L183-N186 PolarHBondContact O-N 3.33Å; L183-A187 PolarHBondContact O-N 3.34Å
184K94.5Very high96.1Very high88 Ų8840.4 Ų40.438%0.38320%0.204SC..Hα-helixtrans-54.9-41.5179.9-65.4-173.5174.4-162.50111.9A132 K133 F134 A187 M188A132-K184 WeakPolarHBondContact O-CD 3.32Å; A132-K184 WeakPolarHBondContact O-CG 3.26Å; K133-K184 PolarHBondContact O-NZ 3.46Å; F134-K184 PolarHBondContact O-NZ 3.22Å; K184-A187 PolarHBondContact O-N 3.41Å; K184-M188 WeakPolarHBondContact O-CG 3.4Å; K184-M188 PolarHBondContact O-N 2.9Å
185D93.5Very high96.3Very high42 Ų4236.6 Ų36.623%0.22518%0.18CC..Hα-helixtrans-67.8-40.7178.9-44.8-53.4000111.6Q99 L183 A187 M188 L189Q99-D185 PolarHBondContact NE2-O 2.87Å; L183-D185 PolarHBondContact O-N 3.48Å; D185-A187 PolarHBondContact O-N 2.97Å; D185-M188 HydrophobicContact CB-CE 4.38Å; D185-M188 PolarHBondContact O-N 2.79Å; D185-M188 WeakPolarHBondContact OD1-CE 3.28Å; D185-L189 PolarHBondContact O-N 3.35Å
186N94.6Very high96.3Very high51 Ų5135.7 Ų35.727%0.27318%0.177SC..Hα-helixtrans-64.8-37.6172.4-71.5-10.5000111.8M182 L183 L189 E190 K313M182-N186 HydrophobicContact CG-CB 3.94Å; L183-N186 HydrophobicContact CB-CB 4.33Å; L183-N186 PolarHBondContact O-N 3.33Å; N186-L189 WeakPolarHBondContact O-CB 3.42Å; N186-L189 PolarHBondContact O-N 3.42Å; N186-L189 VanDerWaalsContact O-N 3.09Å; N186-E190 WeakPolarHBondContact O-CG 3.4Å; N186-E190 PolarHBondContact O-N 2.8Å; N186-K313 VanDerWaalsContact OD1-CE 3.31Å; N186-K313 WeakPolarHBondContact OD1-CE 3.49Å; N186-K313 PolarHBondContact OD1-NZ 3.07Å
187A97.9Very high96.3Very high0 Ų036.7 Ų36.70%018%0.183CC..Hα-helixtrans-66.2-37.8176.500000112.4Q131 A132 M182 L183 K184 D185 L189 Y191Q131-A187 HydrophobicContact CB-CB 4.06Å; Q131-A187 HydrophobicContact CG-CB 3.81Å; A132-A187 HydrophobicContact CB-CB 4.12Å; M182-A187 HydrophobicContact CG-CB 4.15Å; M182-A187 VanDerWaalsContact SD-CA 3.59Å; M182-A187 HydrophobicContact SD-CB 3.83Å; L183-A187 PolarHBondContact O-N 3.34Å; K184-A187 PolarHBondContact O-N 3.41Å; D185-A187 PolarHBondContact O-N 2.97Å; A187-L189 VanDerWaalsContact C-N 3.28Å; A187-L189 PolarHBondContact O-N 3.21Å; A187-Y191 WeakPolarHBondContact O-CB 3.36Å; A187-Y191 PolarHBondContact O-N 2.84Å
188M98.4Very high96.4Very high15 Ų1535.3 Ų35.37%0.07417%0.17CC..Hα-helixtrans-64.7-31.3170-68.6-170.1-65.300112.4Q99 K100 F103 A132 K184 D185 L192Q99-M188 VanDerWaalsContact NE2-CB 3.31Å; K100-M188 HydrophobicContact CB-CE 4.01Å; K100-M188 HydrophobicContact CB-SD 3.98Å; K100-M188 HydrophobicContact CG-CE 4.34Å; K100-M188 HydrophobicContact CG-SD 3.96Å; F103-M188 HydrophobicContact CB-CB 3.95Å; F103-M188 HydrophobicContact CB-CG 4.18Å; F103-M188 HydrophobicContact CB-SD 4.32Å; F103-M188 HydrophobicContact CD1-CB 4.21Å; F103-M188 HydrophobicContact CD1-CG 3.5Å; F103-M188 VanDerWaalsContact CD1-CG 3.5Å; F103-M188 HydrophobicContact CD1-SD 3.45Å; F103-M188 WeakPolarHBondContact CD1-SD 3.46Å; F103-M188 HydrophobicContact CD2-CB 4.08Å; F103-M188 HydrophobicContact CD2-CG 4.01Å; F103-M188 HydrophobicContact CE1-CG 3.79Å; F103-M188 HydrophobicContact CE1-SD 3.95Å; F103-M188 HydrophobicContact CE2-CG 4.25Å; F103-M188 HydrophobicContact CG-CB 3.82Å; F103-M188 HydrophobicContact CG-CG 3.62Å; F103-M188 HydrophobicContact CG-SD 4.01Å; F103-M188 HydrophobicContact CZ-CG 4.16Å; A132-M188 HydrophobicContact CB-CG 3.63Å; K184-M188 WeakPolarHBondContact O-CG 3.4Å; K184-M188 PolarHBondContact O-N 2.9Å; D185-M188 HydrophobicContact CB-CE 4.38Å; D185-M188 PolarHBondContact O-N 2.79Å; D185-M188 WeakPolarHBondContact OD1-CE 3.28Å; M188-L192 WeakPolarHBondContact O-CG 3.14Å; M188-L192 PolarHBondContact O-N 2.79Å
189L97.4Very high96.5Very high25 Ų2531.7 Ų31.713%0.13115%0.153CC..Hα-helixtrans-76.2-45.3178.7-170.861.3000111.6V89 Q99 D185 N186 A187 Y191 L192 K193V89-L189 HydrophobicContact CG2-CD1 4.46Å; Q99-L189 HydrophobicContact CG-CD1 4.17Å; Q99-L189 VanDerWaalsContact NE2-N 3.13Å; D185-L189 PolarHBondContact O-N 3.35Å; N186-L189 WeakPolarHBondContact O-CB 3.42Å; N186-L189 PolarHBondContact O-N 3.42Å; N186-L189 VanDerWaalsContact O-N 3.09Å; A187-L189 VanDerWaalsContact C-N 3.28Å; A187-L189 PolarHBondContact O-N 3.21Å; L189-Y191 VanDerWaalsContact C-N 3.32Å; L189-Y191 PolarHBondContact O-N 2.95Å; L189-L192 CarbonylContact O-C 3.47Å; L189-L192 PolarHBondContact O-N 3.4Å; L189-K193 HydrophobicContact CG-CD 4.09Å; L189-K193 HydrophobicContact CG-CG 4.42Å; L189-K193 WeakPolarHBondContact O-CG 3.4Å; L189-K193 PolarHBondContact O-N 2.95Å
190E98Very high96.6Very high38 Ų3832.6 Ų32.618%0.17816%0.157CC..Hα-helixtrans-63.5-37.4176.1-67-54.8145.500111.9Y128 M182 N186 L192 K193 I194Y128-E190 HydrophobicContact CD1-CB 4.01Å; Y128-E190 HydrophobicContact CE1-CB 3.67Å; Y128-E190 HydrophobicContact CE1-CG 4.36Å; M182-E190 HydrophobicContact CE-CG 4.45Å; M182-E190 HydrophobicContact SD-CG 4.34Å; N186-E190 WeakPolarHBondContact O-CG 3.4Å; N186-E190 PolarHBondContact O-N 2.8Å; E190-L192 VanDerWaalsContact C-N 3.33Å; E190-L192 PolarHBondContact O-N 2.81Å; E190-K193 PolarHBondContact O-N 2.74Å; E190-K193 IonicContact OE1-NZ 3.29Å; E190-K193 PolarHBondContact OE1-NZ 3.31Å; E190-K193 IonicContact OE2-NZ 2.74Å; E190-K193 PolarHBondContact OE2-NZ 2.86Å; E190-I194 WeakPolarHBondContact O-CG1 3.48Å; E190-I194 PolarHBondContact O-N 2.88Å; E190-I194 VanDerWaalsContact O-N 3.09Å
191Y98.8Very high96.8Very high5 Ų523.9 Ų23.92%0.0212%0.124CC..Hα-helixtrans-53.8-49.6167.9-173.6-72.8000111.4F103 V106 K107 I110 L125 A129 A187 L189 A195F103-Y191 AromaticContact CD2-CD1 3.68Å; F103-Y191 HydrophobicContact CD2-CD1 3.68Å; F103-Y191 HydrophobicContact CD2-CD2 4.11Å; F103-Y191 HydrophobicContact CD2-CE1 4.33Å; F103-Y191 AromaticContact CD2-CG 3.6Å; F103-Y191 HydrophobicContact CD2-CG 3.6Å; F103-Y191 HydrophobicContact CE2-CD1 4.03Å; F103-Y191 AromaticContact CE2-CD2 3.61Å; F103-Y191 HydrophobicContact CE2-CD2 3.61Å; F103-Y191 HydrophobicContact CE2-CE2 4.11Å; F103-Y191 AromaticContact CE2-CG 3.58Å; F103-Y191 HydrophobicContact CE2-CG 3.58Å; V106-Y191 HydrophobicContact CG1-CE1 4.24Å; K107-Y191 WeakPolarHBondContact CA-OH 3.19Å; K107-Y191 HydrophobicContact CB-CE1 4.24Å; K107-Y191 HydrophobicContact CD-CE2 4.5Å; K107-Y191 HydrophobicContact CG-CE2 4.3Å; I110-Y191 HydrophobicContact CD1-CE1 4.32Å; L125-Y191 HydrophobicContact CB-CD2 3.96Å; L125-Y191 HydrophobicContact CB-CE2 3.53Å; L125-Y191 HydrophobicContact CD2-CD1 4.04Å; L125-Y191 HydrophobicContact CD2-CD2 3.76Å; L125-Y191 HydrophobicContact CD2-CE1 4.21Å; L125-Y191 HydrophobicContact CD2-CE2 3.98Å; L125-Y191 HydrophobicContact CD2-CG 3.77Å; L125-Y191 VanDerWaalsContact CD2-O 3.25Å; L125-Y191 WeakPolarHBondContact CD2-O 3.4Å; L125-Y191 HydrophobicContact CG-CD2 4.43Å; L125-Y191 HydrophobicContact CG-CE2 4.22Å; L125-Y191 WeakPolarHBondContact O-CD2 3.29Å; L125-Y191 WeakPolarHBondContact O-CE2 3.46Å; A129-Y191 HydrophobicContact CB-CD2 4.23Å; A129-Y191 HydrophobicContact CB-CE2 4.07Å; A187-Y191 WeakPolarHBondContact O-CB 3.36Å; A187-Y191 PolarHBondContact O-N 2.84Å; L189-Y191 VanDerWaalsContact C-N 3.32Å; L189-Y191 PolarHBondContact O-N 2.95Å; Y191-A195 HydrophobicContact CD1-CB 4.34Å; Y191-A195 HydrophobicContact CE1-CB 4.25Å; Y191-A195 WeakPolarHBondContact O-CB 3.46Å; Y191-A195 PolarHBondContact O-N 2.78Å
192L98.7Very high97.1Very high0 Ų023 Ų230%012%0.115CC..Hα-helixtrans-68.8-36.8-179.6-76.1171.6000112.8V89 L93 Q99 F102 F103 V106 M188 L189 E190 I194 A195 Q196V89-L192 HydrophobicContact CB-CB 4.21Å; V89-L192 HydrophobicContact CG1-CB 4.21Å; V89-L192 HydrophobicContact CG2-CB 3.97Å; L93-L192 HydrophobicContact CD1-CD1 3.9Å; Q99-L192 HydrophobicContact CG-CD1 4.17Å; F102-L192 HydrophobicContact CB-CD1 3.91Å; F102-L192 HydrophobicContact CB-CD2 4.27Å; F103-L192 HydrophobicContact CB-CD1 4.15Å; F103-L192 HydrophobicContact CB-CG 4.27Å; V106-L192 HydrophobicContact CB-CD2 4.02Å; V106-L192 HydrophobicContact CG1-CD2 4.36Å; V106-L192 HydrophobicContact CG2-CD2 3.82Å; M188-L192 WeakPolarHBondContact O-CG 3.14Å; M188-L192 PolarHBondContact O-N 2.79Å; L189-L192 CarbonylContact O-C 3.47Å; L189-L192 PolarHBondContact O-N 3.4Å; E190-L192 VanDerWaalsContact C-N 3.33Å; E190-L192 PolarHBondContact O-N 2.81Å; L192-I194 VanDerWaalsContact C-N 3.3Å; L192-I194 PolarHBondContact O-N 3.39Å; L192-A195 PolarHBondContact O-N 3.48Å; L192-Q196 WeakPolarHBondContact O-CB 3.47Å; L192-Q196 PolarHBondContact O-N 2.94Å
193K98.4Very high97.3Very high23 Ų2322.1 Ų22.110%0.111%0.111CC..Hα-helixtrans-64.9-34178.4-75171.263.6-125.60112.3V89 A90 L189 E190 Q196 E520V89-K193 HydrophobicContact CG2-CB 4.33Å; V89-K193 HydrophobicContact CG2-CG 3.65Å; A90-K193 HydrophobicContact CB-CD 4.12Å; A90-K193 HydrophobicContact CB-CG 4.23Å; L189-K193 HydrophobicContact CG-CD 4.09Å; L189-K193 HydrophobicContact CG-CG 4.42Å; L189-K193 WeakPolarHBondContact O-CG 3.4Å; L189-K193 PolarHBondContact O-N 2.95Å; E190-K193 PolarHBondContact O-N 2.74Å; E190-K193 IonicContact OE1-NZ 3.29Å; E190-K193 PolarHBondContact OE1-NZ 3.31Å; E190-K193 IonicContact OE2-NZ 2.74Å; E190-K193 PolarHBondContact OE2-NZ 2.86Å; K193-Q196 WeakPolarHBondContact O-CG 3.13Å; K193-E520 HydrophobicContact CB-CG 4.28Å; K193-E520 WeakPolarHBondContact CE-OE2 3.29Å; K193-E520 IonicContact NZ-OE1 2.88Å; K193-E520 PolarHBondContact NZ-OE1 3.03Å; K193-E520 IonicContact NZ-OE2 2.65Å; K193-E520 PolarHBondContact NZ-OE2 3.48Å
194I98.4Very high97.5Very high8 Ų820.9 Ų20.94%0.04111%0.105CC..Hα-helixtrans-78.6-43.1172-64.9168.5000110.6T121 L124 L125 Y128 E190 L192 Q196 D197 E520 V527T121-I194 HydrophobicContact CG2-CG2 3.64Å; L124-I194 HydrophobicContact CD2-CD1 3.94Å; L124-I194 HydrophobicContact CG-CD1 4.3Å; L125-I194 HydrophobicContact CD2-CB 3.91Å; L125-I194 HydrophobicContact CD2-CG2 3.86Å; L125-I194 HydrophobicContact CG-CG2 4.24Å; Y128-I194 HydrophobicContact CD2-CD1 4.11Å; Y128-I194 HydrophobicContact CE2-CD1 3.52Å; E190-I194 WeakPolarHBondContact O-CG1 3.48Å; E190-I194 PolarHBondContact O-N 2.88Å; E190-I194 VanDerWaalsContact O-N 3.09Å; L192-I194 VanDerWaalsContact C-N 3.3Å; L192-I194 PolarHBondContact O-N 3.39Å; I194-Q196 VanDerWaalsContact C-N 3.34Å; I194-Q196 PolarHBondContact O-N 2.86Å; I194-D197 PolarHBondContact O-N 3.36Å; I194-E520 HydrophobicContact CG1-CG 4.25Å; I194-V527 HydrophobicContact CD1-CG1 3.9Å; I194-V527 HydrophobicContact CD1-CG2 4.16Å; I194-V527 HydrophobicContact CG1-CG1 3.98Å
195A98.6Very high97.6Very high0 Ų018.6 Ų18.60%09%0.094CC..Hα-helixtrans-68.7-27.3-176.700000114V106 I110 L125 Y191 L192 D197 L198 Y201V106-A195 HydrophobicContact CG1-CB 3.71Å; I110-A195 HydrophobicContact CD1-CB 4.02Å; L125-A195 HydrophobicContact CD1-CB 4.36Å; L125-A195 HydrophobicContact CD2-CB 4.46Å; Y191-A195 HydrophobicContact CD1-CB 4.34Å; Y191-A195 HydrophobicContact CE1-CB 4.25Å; Y191-A195 WeakPolarHBondContact O-CB 3.46Å; Y191-A195 PolarHBondContact O-N 2.78Å; L192-A195 PolarHBondContact O-N 3.48Å; A195-D197 PolarHBondContact O-N 2.72Å; A195-L198 HydrophobicContact CB-CD1 4.5Å; A195-L198 WeakPolarHBondContact O-CB 3.2Å; A195-L198 PolarHBondContact O-N 2.88Å; A195-Y201 HydrophobicContact CB-CD2 4.49Å; A195-Y201 VanDerWaalsContact O-CB 3.31Å; A195-Y201 WeakPolarHBondContact O-CB 3.39Å; A195-Y201 VanDerWaalsContact O-CD2 3.25Å; A195-Y201 WeakPolarHBondContact O-CD2 3.44Å
196Q98.1Very high97.8Very high3 Ų317.1 Ų17.11%0.0149%0.086CC..THydrogen-bonded Turntrans-64.2-23.6179.166.9173.8-1500113.8D88 V89 L192 K193 I194 Y201 K564D88-Q196 PolarHBondContact OD1-NE2 3.21Å; D88-Q196 PolarHBondContact OD1-OE1 3Å; V89-Q196 HydrophobicContact CG1-CB 4.26Å; V89-Q196 HydrophobicContact CG2-CG 4.46Å; V89-Q196 VanDerWaalsContact N-OE1 3.11Å; L192-Q196 WeakPolarHBondContact O-CB 3.47Å; L192-Q196 PolarHBondContact O-N 2.94Å; K193-Q196 WeakPolarHBondContact O-CG 3.13Å; I194-Q196 VanDerWaalsContact C-N 3.34Å; I194-Q196 PolarHBondContact O-N 2.86Å; Q196-Y201 HydrophobicContact CB-CD1 4.01Å; Q196-Y201 HydrophobicContact CB-CE1 3.65Å; Q196-Y201 HydrophobicContact CB-CE2 4.28Å; Q196-Y201 HydrophobicContact CB-CG 4.48Å; Q196-K564 PolarHBondContact O-NZ 3.25Å
197D98.1Very high98Very high21 Ų2118.9 Ų18.911%0.1129%0.092CC..THydrogen-bonded Turntrans-83.1-13.2-178.5-63.9-20.1000113.4I194 A195 T519 E520 K564 Y565I194-D197 PolarHBondContact O-N 3.36Å; A195-D197 PolarHBondContact O-N 2.72Å; D197-T519 HydrophobicContact CB-CG2 4.01Å; D197-T519 WeakPolarHBondContact OD2-CA 3.32Å; D197-T519 WeakPolarHBondContact OD2-CB 3.48Å; D197-E520 PolarHBondContact OD2-N 2.95Å; D197-K564 WeakPolarHBondContact O-CB 3.21Å; D197-K564 WeakPolarHBondContact O-CD 3.36Å; D197-Y565 VanDerWaalsContact OD1-CE2 3.26Å; D197-Y565 WeakPolarHBondContact OD1-CE2 3.28Å; D197-Y565 PolarHBondContact OD1-OH 2.82Å; D197-Y565 VanDerWaalsContact OD1-OH 3.05Å
198L98.3Very high98Very high9 Ų919.1 Ų19.15%0.0479%0.093CC..SBendtrans-61.2137.8175-64.1174.9000110.3I110 I115 C117 T121 A195 M200 Y201 K564I110-L198 HydrophobicContact CD1-CD1 3.63Å; I110-L198 HydrophobicContact CG1-CD1 4.11Å; I115-L198 HydrophobicContact CG2-CB 4.33Å; I115-L198 HydrophobicContact CG2-CD1 4Å; C117-L198 HydrophobicContact CB-CD1 4.02Å; C117-L198 HydrophobicContact CB-CD2 4.4Å; T121-L198 HydrophobicContact CG2-CD2 4.26Å; A195-L198 HydrophobicContact CB-CD1 4.5Å; A195-L198 WeakPolarHBondContact O-CB 3.2Å; A195-L198 PolarHBondContact O-N 2.88Å; L198-M200 PolarHBondContact O-N 2.9Å; L198-M200 VanDerWaalsContact O-N 3.15Å; L198-Y201 WeakPolarHBondContact O-CB 3.39Å; L198-Y201 PolarHBondContact O-N 2.65Å; L198-K564 PolarHBondContact O-NZ 3.28Å
199E97.9Very high98Very high24 Ų2422 Ų2211%0.11211%0.106CC..THydrogen-bonded Turntrans-60.4-33.9-169.3-56.996.2130.600112.5I203 L234 H554E199-I203 WeakPolarHBondContact O-CD1 3.49Å; E199-L234 HydrophobicContact CB-CB 4.06Å; E199-L234 HydrophobicContact CB-CD2 4.25Å; E199-L234 HydrophobicContact CG-CB 4.26Å; E199-H554 IonicContact OE1-CE1 2.73Å; E199-H554 IonicContact OE1-CG 3.86Å; E199-H554 IonicContact OE1-ND1 2.82Å; E199-H554 PolarHBondContact OE1-ND1 3.34Å; E199-H554 IonicContact OE2-ND1 3.22Å
200M98.2Very high97.9Very high20 Ų2020.9 Ų20.910%0.09910%0.1CC..THydrogen-bonded Turntrans-88.1-8.3178.8-57-172.164.900114.5E114 I115 Y116 L198 G202 I203 Y205 K233 L234E114-M200 WeakPolarHBondContact O-CE 3.35Å; I115-M200 HydrophobicContact CG2-CB 4.22Å; Y116-M200 VanDerWaalsContact CB-SD 3.55Å; Y116-M200 PolarHBondContact N-SD 2.74Å; L198-M200 PolarHBondContact O-N 2.9Å; L198-M200 VanDerWaalsContact O-N 3.15Å; M200-G202 PolarHBondContact O-N 2.73Å; M200-I203 PolarHBondContact O-N 3.16Å; M200-Y205 HydrophobicContact CB-CE2 4.47Å; M200-Y205 HydrophobicContact CE-CE2 3.87Å; M200-Y205 WeakPolarHBondContact CG-OH 3.5Å; M200-K233 HydrophobicContact CE-CB 4.42Å; M200-K233 HydrophobicContact CE-CD 4.49Å; M200-L234 HydrophobicContact CG-CD2 3.54Å; M200-L234 HydrophobicContact SD-CD2 3.77Å
201Y98.3Very high97.8Very high10 Ų1024.6 Ų24.64%0.03912%0.116CC..THydrogen-bonded Turntrans-63.3128-175.5171.2-81.1000112.1F85 V89 V106 A195 Q196 L198 I203 K564F85-Y201 AromaticContact CD1-CE1 3.92Å; F85-Y201 HydrophobicContact CD1-CE1 3.92Å; F85-Y201 HydrophobicContact CD1-CE2 4.22Å; F85-Y201 AromaticContact CD1-CZ 3.67Å; F85-Y201 HydrophobicContact CE1-CE2 4.24Å; V89-Y201 VanDerWaalsContact CG1-OH 3.25Å; V89-Y201 WeakPolarHBondContact CG1-OH 3.46Å; V106-Y201 HydrophobicContact CG1-CD2 4.02Å; V106-Y201 HydrophobicContact CG1-CE2 3.96Å; V106-Y201 HydrophobicContact CG2-CD2 4.27Å; V106-Y201 HydrophobicContact CG2-CE2 3.65Å; A195-Y201 HydrophobicContact CB-CD2 4.49Å; A195-Y201 VanDerWaalsContact O-CB 3.31Å; A195-Y201 WeakPolarHBondContact O-CB 3.39Å; A195-Y201 VanDerWaalsContact O-CD2 3.25Å; A195-Y201 WeakPolarHBondContact O-CD2 3.44Å; Q196-Y201 HydrophobicContact CB-CD1 4.01Å; Q196-Y201 HydrophobicContact CB-CE1 3.65Å; Q196-Y201 HydrophobicContact CB-CE2 4.28Å; Q196-Y201 HydrophobicContact CB-CG 4.48Å; L198-Y201 WeakPolarHBondContact O-CB 3.39Å; L198-Y201 PolarHBondContact O-N 2.65Å; Y201-I203 VanDerWaalsContact C-N 3.27Å; Y201-I203 WeakPolarHBondContact O-CG1 3.22Å; Y201-I203 PolarHBondContact O-N 2.89Å; Y201-K564 PolarHBondContact O-NZ 2.8Å; Y201-K564 VanDerWaalsContact O-NZ 3.07Å
202G96.6Very high97.7Very high12 Ų1230.6 Ų30.612%0.12414%0.142CC..THydrogen-bonded Turntrans80.2-4.5176.300000115.3M200M200-G202 PolarHBondContact O-N 2.73Å
203I97.8Very high97.5Very high19 Ų1932 Ų3210%0.09716%0.156CC..  trans-91.1120.7-167.1-48.7-162.7000111.8E199 M200 Y201 Y205 D221 Y228E199-I203 WeakPolarHBondContact O-CD1 3.49Å; M200-I203 PolarHBondContact O-N 3.16Å; Y201-I203 VanDerWaalsContact C-N 3.27Å; Y201-I203 WeakPolarHBondContact O-CG1 3.22Å; Y201-I203 PolarHBondContact O-N 2.89Å; I203-Y205 HydrophobicContact CB-CD2 4.36Å; I203-Y205 HydrophobicContact CB-CE2 3.75Å; I203-Y205 HydrophobicContact CG2-CD1 4.4Å; I203-Y205 HydrophobicContact CG2-CD2 4.13Å; I203-Y205 HydrophobicContact CG2-CE1 4.12Å; I203-Y205 HydrophobicContact CG2-CE2 3.79Å; I203-Y205 HydrophobicContact CG2-CG 4.41Å; I203-Y205 WeakPolarHBondContact O-CD2 3.43Å; I203-Y205 PolarHBondContact O-N 3.45Å; I203-D221 HydrophobicContact CG1-CB 4.14Å; I203-Y228 WeakPolarHBondContact CD1-OH 3.16Å
204N97.3Very high97.5Very high25 Ų2533.1 Ų33.113%0.13417%0.165CC..EExtended strand (participates in β ladder)trans-88.3103.7169.7-81-108.3000109.9F206 V220 R279 L283N204-F206 HydrophobicContact CB-CE2 3.72Å; N204-F206 HydrophobicContact CB-CZ 4.06Å; N204-F206 WeakPolarHBondContact O-CD2 3.22Å; N204-F206 WeakPolarHBondContact O-CE2 3.26Å; N204-V220 HydrophobicContact CB-CB 4.38Å; N204-V220 PolarHBondContact N-O 2.93Å; N204-V220 PolarHBondContact O-N 3.49Å; N204-R279 PolarHBondContact OD1-NH2 2.91Å; N204-L283 HydrophobicContact CB-CD1 3.91Å; N204-L283 WeakPolarHBondContact OD1-CD1 3.34Å
205Y97.4Very high97.4Very high40 Ų4037 Ų3716%0.15718%0.183CC..EExtended strand (participates in β ladder)trans-80.7137.5177.5-62.9-93.3000112.8M200 I203 W217 L218 Y228 K233M200-Y205 HydrophobicContact CB-CE2 4.47Å; M200-Y205 HydrophobicContact CE-CE2 3.87Å; M200-Y205 WeakPolarHBondContact CG-OH 3.5Å; I203-Y205 HydrophobicContact CB-CD2 4.36Å; I203-Y205 HydrophobicContact CB-CE2 3.75Å; I203-Y205 HydrophobicContact CG2-CD1 4.4Å; I203-Y205 HydrophobicContact CG2-CD2 4.13Å; I203-Y205 HydrophobicContact CG2-CE1 4.12Å; I203-Y205 HydrophobicContact CG2-CE2 3.79Å; I203-Y205 HydrophobicContact CG2-CG 4.41Å; I203-Y205 WeakPolarHBondContact O-CD2 3.43Å; I203-Y205 PolarHBondContact O-N 3.45Å; Y205-W217 HydrophobicContact CD1-CB 4.24Å; Y205-L218 CarbonylContact C-O 3.46Å; Y205-L218 WeakPolarHBondContact CA-O 3.19Å; Y205-Y228 HydrophobicContact CD1-CE2 4.45Å; Y205-Y228 HydrophobicContact CE1-CD1 4.41Å; Y205-Y228 HydrophobicContact CE1-CD2 4.26Å; Y205-Y228 HydrophobicContact CE1-CE1 4.08Å; Y205-Y228 AromaticContact CE1-CE2 3.97Å; Y205-Y228 HydrophobicContact CE1-CE2 3.97Å; Y205-Y228 AromaticContact CE1-CZ 3.89Å; Y205-K233 HydrophobicContact CD1-CD 4.28Å; Y205-K233 HydrophobicContact CD1-CG 4.2Å; Y205-K233 HydrophobicContact CE1-CB 3.84Å; Y205-K233 HydrophobicContact CE1-CD 4.34Å; Y205-K233 HydrophobicContact CE1-CG 3.98Å; Y205-K233 PolarHBondContact OH-O 3.26Å
206F97.4Very high97.4Very high12 Ų1237.1 Ų37.15%0.05318%0.183CC..EExtended strand (participates in β ladder)trans-134.7137.2174.3-61.1-76.1000111.8N204 I208 W217 L218 V220 I276 R279 I280 L283N204-F206 HydrophobicContact CB-CE2 3.72Å; N204-F206 HydrophobicContact CB-CZ 4.06Å; N204-F206 WeakPolarHBondContact O-CD2 3.22Å; N204-F206 WeakPolarHBondContact O-CE2 3.26Å; F206-I208 PolarHBondContact O-N 2.9Å; F206-W217 CarbonylContact O-C 3.55Å; F206-W217 WeakPolarHBondContact O-CA 3.39Å; F206-L218 HydrophobicContact CB-CB 4.45Å; F206-L218 PolarHBondContact N-O 2.88Å; F206-L218 PolarHBondContact O-N 3.35Å; F206-V220 HydrophobicContact CD2-CG2 4.02Å; F206-V220 HydrophobicContact CE2-CB 4.47Å; F206-V220 HydrophobicContact CE2-CG2 3.93Å; F206-I276 HydrophobicContact CB-CG2 4.4Å; F206-I276 HydrophobicContact CD1-CG2 3.78Å; F206-I276 HydrophobicContact CG-CG2 4.37Å; F206-R279 HydrophobicContact CE1-CB 4.48Å; F206-R279 HydrophobicContact CE1-CG 3.93Å; F206-R279 HydrophobicContact CZ-CG 3.87Å; F206-I280 HydrophobicContact CB-CD1 4.03Å; F206-I280 HydrophobicContact CB-CG1 4.31Å; F206-I280 HydrophobicContact CD1-CD1 4.42Å; F206-I280 HydrophobicContact CD1-CG1 3.98Å; F206-I280 HydrophobicContact CD2-CD1 4.26Å; F206-I280 HydrophobicContact CD2-CG1 3.66Å; F206-I280 HydrophobicContact CE1-CG1 4.25Å; F206-I280 HydrophobicContact CE2-CG1 3.92Å; F206-I280 HydrophobicContact CG-CD1 3.96Å; F206-I280 HydrophobicContact CG-CG1 3.68Å; F206-I280 HydrophobicContact CZ-CG1 4.23Å; F206-L283 HydrophobicContact CE2-CD1 3.92Å; F206-L283 HydrophobicContact CZ-CD1 3.57Å
207E97.6Very high97.5Very high88 Ų8838.6 Ų38.641%0.41119%0.189SC..EExtended strand (participates in β ladder)trans-71.7124.6171.1-61.5-172.8125.700110.5W217 K230 P272E207-W217 HydrophobicContact CB-CZ3 4.48Å; E207-W217 HydrophobicContact CG-CE3 3.91Å; E207-W217 HydrophobicContact CG-CH2 3.53Å; E207-W217 HydrophobicContact CG-CZ2 4.28Å; E207-W217 HydrophobicContact CG-CZ3 3.34Å; E207-K230 IonicContact OE1-NZ 3.64Å; E207-K230 PolarHBondContact OE1-NZ 3.11Å; E207-P272 VanDerWaalsContact O-CD 3.27Å; E207-P272 WeakPolarHBondContact O-CD 3.25Å
208I98.1Very high97.5Very high4 Ų437.6 Ų37.62%0.02118%0.184CC..EExtended strand (participates in β ladder)trans-135.4167.2178.561.6153.1000110.7F206 L216 L218 I227 F269 Y270 F583F206-I208 PolarHBondContact O-N 2.9Å; I208-L216 HydrophobicContact CD1-CB 4.41Å; I208-L216 HydrophobicContact CG1-CB 4.09Å; I208-L216 WeakPolarHBondContact CG1-O 3.4Å; I208-L216 PolarHBondContact N-O 3.12Å; I208-L216 PolarHBondContact O-N 2.88Å; I208-L216 VanDerWaalsContact O-O 3.11Å; I208-L218 HydrophobicContact CD1-CB 3.94Å; I208-L218 HydrophobicContact CG1-CB 4.09Å; I208-L218 HydrophobicContact CG2-CB 3.94Å; I208-I227 HydrophobicContact CD1-CD1 4.21Å; I208-F269 HydrophobicContact CB-CB 4.39Å; I208-F269 HydrophobicContact CB-CD2 3.8Å; I208-F269 HydrophobicContact CB-CE2 4.44Å; I208-F269 HydrophobicContact CB-CG 4.3Å; I208-F269 HydrophobicContact CD1-CB 3.93Å; I208-F269 HydrophobicContact CD1-CD1 4.41Å; I208-F269 HydrophobicContact CD1-CD2 4.28Å; I208-F269 HydrophobicContact CD1-CG 3.97Å; I208-F269 HydrophobicContact CG2-CD2 3.41Å; I208-F269 VanDerWaalsContact CG2-CD2 3.41Å; I208-F269 HydrophobicContact CG2-CE2 3.56Å; I208-F269 HydrophobicContact CG2-CG 4.23Å; I208-F269 HydrophobicContact CG2-CZ 4.44Å; I208-Y270 CarbonylContact C-O 3.51Å; I208-Y270 WeakPolarHBondContact CA-O 3.35Å; I208-F583 HydrophobicContact CD1-CE2 4.02Å; I208-F583 HydrophobicContact CD1-CZ 4.21Å
209K98.3Very high97.5Very high76 Ų7637.2 Ų37.233%0.3318%0.181SC..EExtended strand (participates in β ladder)trans-130144.8168.5-68.8174.3175.6-86.10111.1G213 T214 E215 F269 Y270K209-G213 WeakPolarHBondContact CD-O 3.3Å; K209-G213 WeakPolarHBondContact CG-O 3.41Å; K209-G213 PolarHBondContact NZ-O 2.7Å; K209-T214 VanDerWaalsContact CA-O 3.28Å; K209-T214 WeakPolarHBondContact CA-O 3.31Å; K209-E215 WeakPolarHBondContact CE-OE1 3.39Å; K209-E215 IonicContact NZ-OE1 3.26Å; K209-E215 PolarHBondContact NZ-OE1 2.93Å; K209-F269 CarbonylContact O-C 3.53Å; K209-F269 WeakPolarHBondContact O-CA 3.45Å; K209-F269 WeakPolarHBondContact O-CB 3.38Å; K209-Y270 PolarHBondContact N-O 3.12Å; K209-Y270 PolarHBondContact O-N 3.24Å
210N96.8Very high97.5Very high2 Ų236 Ų361%0.01118%0.176CC..  trans-77.5-172.8168.472.52.3000110.9K212 G213 T214 L216 F583 L586N210-K212 VanDerWaalsContact C-N 3.29Å; N210-K212 PolarHBondContact O-N 2.75Å; N210-K212 WeakPolarHBondContact OD1-CB 3.43Å; N210-K212 PolarHBondContact OD1-N 2.87Å; N210-K212 VanDerWaalsContact OD1-N 3.11Å; N210-G213 PolarHBondContact O-N 3.17Å; N210-G213 PolarHBondContact OD1-N 2.92Å; N210-G213 VanDerWaalsContact OD1-N 3.08Å; N210-T214 PolarHBondContact OD1-N 2.89Å; N210-T214 VanDerWaalsContact OD1-N 3.17Å; N210-L216 HydrophobicContact CB-CD1 4.36Å; N210-F583 HydrophobicContact CB-CD1 4.03Å; N210-F583 HydrophobicContact CB-CE1 3.36Å; N210-F583 HydrophobicContact CB-CE2 4.21Å; N210-F583 HydrophobicContact CB-CZ 3.47Å; N210-F583 VanDerWaalsContact CB-CZ 3.47Å; N210-F583 PolarHBondContact ND2-O 3.36Å; N210-L586 PolarHBondContact ND2-OXT 2.73Å
211K95.3Very high97.5Very high116 Ų11635.4 Ų35.450%0.50417%0.173SC..THydrogen-bonded Turntrans-67.9-24.9-178.8-64.5176.9-172.685.10113.5Y270 E584K211-Y270 HydrophobicContact CG-CE2 4.27Å; K211-E584 VanDerWaalsContact CB-OE2 3.23Å; K211-E584 WeakPolarHBondContact CB-OE2 3.46Å; K211-E584 WeakPolarHBondContact CG-OE1 3.4Å; K211-E584 WeakPolarHBondContact CG-OE2 3.32Å; K211-E584 PolarHBondContact N-OE2 2.75Å; K211-E584 IonicContact NZ-OE1 3.47Å; K211-E584 PolarHBondContact NZ-OE1 3.36Å
212K95.4Very high97.4Very high131 Ų13135.2 Ų35.257%0.5717%0.174SC*.THydrogen-bonded Turntrans-77.1-23.5174.3-70.1159.8162.8169.60113.3N210 E584 A585 L586N210-K212 VanDerWaalsContact C-N 3.29Å; N210-K212 PolarHBondContact O-N 2.75Å; N210-K212 WeakPolarHBondContact OD1-CB 3.43Å; N210-K212 PolarHBondContact OD1-N 2.87Å; N210-K212 VanDerWaalsContact OD1-N 3.11Å; K212-E584 WeakPolarHBondContact CD-O 3.28Å; K212-E584 WeakPolarHBondContact CE-O 2.96Å; K212-E584 PolarHBondContact NZ-O 2.83Å; K212-A585 PolarHBondContact NZ-O 3.34Å; K212-L586 WeakPolarHBondContact CD-OXT 3.39Å; K212-L586 PolarHBondContact NZ-OXT 2.83Å
213G95.2Very high97.3Very high29 Ų2935.3 Ų35.330%0.29917%0.171SC..  trans100.43-176.800000115.1K209 N210 E215K209-G213 WeakPolarHBondContact CD-O 3.3Å; K209-G213 WeakPolarHBondContact CG-O 3.41Å; K209-G213 PolarHBondContact NZ-O 2.7Å; N210-G213 PolarHBondContact O-N 3.17Å; N210-G213 PolarHBondContact OD1-N 2.92Å; N210-G213 VanDerWaalsContact OD1-N 3.08Å; G213-E215 PolarHBondContact O-N 2.75Å
214T97.8Very high97.2Very high47 Ų4734.4 Ų34.429%0.28817%0.166SC..  trans-51.8133.1174.1-54.70000110.2K209 N210 L216 L586K209-T214 VanDerWaalsContact CA-O 3.28Å; K209-T214 WeakPolarHBondContact CA-O 3.31Å; N210-T214 PolarHBondContact OD1-N 2.89Å; N210-T214 VanDerWaalsContact OD1-N 3.17Å; T214-L216 HydrophobicContact CG2-CD2 4.03Å; T214-L216 HydrophobicContact CG2-CG 4.14Å; T214-L586 WeakPolarHBondContact CB-O 3.36Å; T214-L586 WeakPolarHBondContact CG2-O 3.49Å; T214-L586 VanDerWaalsContact OG1-C 3.32Å; T214-L586 PolarHBondContact OG1-O 2.75Å; T214-L586 PolarHBondContact OG1-OXT 2.67Å
215E98.1Very high97.3Very high90 Ų9033.2 Ų33.242%0.42116%0.16SC..EExtended strand (participates in β ladder)trans-82.1122.7179.1-49.8-129.6145.700110.8K209 G213 K230K209-E215 WeakPolarHBondContact CE-OE1 3.39Å; K209-E215 IonicContact NZ-OE1 3.26Å; K209-E215 PolarHBondContact NZ-OE1 2.93Å; G213-E215 PolarHBondContact O-N 2.75Å; E215-K230 HydrophobicContact CB-CB 4.41Å; E215-K230 HydrophobicContact CB-CD 3.9Å; E215-K230 HydrophobicContact CB-CG 4.36Å; E215-K230 IonicContact OE2-NZ 3.05Å; E215-K230 PolarHBondContact OE2-NZ 2.83Å
216L98.3Very high97.3Very high2 Ų231.3 Ų31.31%0.0115%0.153CC..EExtended strand (participates in β ladder)trans-136.2160.1-175.5-61.4171.9000110.1I208 N210 T214 I227 Y228 F583 L586I208-L216 HydrophobicContact CD1-CB 4.41Å; I208-L216 HydrophobicContact CG1-CB 4.09Å; I208-L216 WeakPolarHBondContact CG1-O 3.4Å; I208-L216 PolarHBondContact N-O 3.12Å; I208-L216 PolarHBondContact O-N 2.88Å; I208-L216 VanDerWaalsContact O-O 3.11Å; N210-L216 HydrophobicContact CB-CD1 4.36Å; T214-L216 HydrophobicContact CG2-CD2 4.03Å; T214-L216 HydrophobicContact CG2-CG 4.14Å; L216-I227 HydrophobicContact CB-CG2 4.22Å; L216-I227 HydrophobicContact CD1-CG2 4.07Å; L216-Y228 WeakPolarHBondContact CA-O 3.44Å; L216-Y228 WeakPolarHBondContact CD2-O 3.23Å; L216-F583 HydrophobicContact CD1-CD2 4.05Å; L216-F583 HydrophobicContact CD1-CE2 3.58Å; L216-F583 HydrophobicContact CD1-CZ 4.29Å; L216-L586 HydrophobicContact CD1-CB 4.37Å; L216-L586 HydrophobicContact CD1-CD1 4Å; L216-L586 HydrophobicContact CD2-CB 4.47Å; L216-L586 HydrophobicContact CD2-CD1 3.98Å
217W98.4Very high97.4Very high34 Ų3430.8 Ų30.813%0.12915%0.15CC..EExtended strand (participates in β ladder)trans-100.7135.2165.9-58.795.7000110.5Y205 F206 E207 I227 Y228 K230 K233Y205-W217 HydrophobicContact CD1-CB 4.24Å; F206-W217 CarbonylContact O-C 3.55Å; F206-W217 WeakPolarHBondContact O-CA 3.39Å; E207-W217 HydrophobicContact CB-CZ3 4.48Å; E207-W217 HydrophobicContact CG-CE3 3.91Å; E207-W217 HydrophobicContact CG-CH2 3.53Å; E207-W217 HydrophobicContact CG-CZ2 4.28Å; E207-W217 HydrophobicContact CG-CZ3 3.34Å; W217-I227 WeakPolarHBondContact O-CA 3.41Å; W217-Y228 HydrophobicContact CB-CD2 4.28Å; W217-Y228 PolarHBondContact N-O 3.01Å; W217-Y228 PolarHBondContact O-N 2.77Å; W217-K230 HydrophobicContact CZ2-CD 4.42Å; W217-K230 PolarHBondContact NE1-O 3.35Å; W217-K233 VanDerWaalsContact CZ2-NZ 3.29Å
218L98.6Very high97.4Very high0 Ų026.7 Ų26.70%013%0.131CC..EExtended strand (participates in β ladder)trans-94.9117.8161.2176.971.3000108.4Y205 F206 I208 V220 L225 I227 F269 I280Y205-L218 CarbonylContact C-O 3.46Å; Y205-L218 WeakPolarHBondContact CA-O 3.19Å; F206-L218 HydrophobicContact CB-CB 4.45Å; F206-L218 PolarHBondContact N-O 2.88Å; F206-L218 PolarHBondContact O-N 3.35Å; I208-L218 HydrophobicContact CD1-CB 3.94Å; I208-L218 HydrophobicContact CG1-CB 4.09Å; I208-L218 HydrophobicContact CG2-CB 3.94Å; L218-V220 HydrophobicContact CD2-CG2 4Å; L218-V220 HydrophobicContact CG-CG2 4.08Å; L218-L225 HydrophobicContact CD1-CB 4.27Å; L218-L225 HydrophobicContact CD1-CD2 4.28Å; L218-I227 HydrophobicContact CD1-CD1 3.62Å; L218-F269 HydrophobicContact CD2-CE1 3.85Å; L218-F269 HydrophobicContact CD2-CE2 4.17Å; L218-F269 HydrophobicContact CD2-CZ 3.48Å; L218-F269 VanDerWaalsContact CD2-CZ 3.48Å; L218-I280 HydrophobicContact CD2-CD1 4.15Å; L218-I280 HydrophobicContact CD2-CG2 3.95Å
219G98.4Very high97.4Very high0 Ų030.1 Ų30.10%015%0.147CC..EExtended strand (participates in β ladder)trans-88.9130.7162.800000110.5L225 N226G219-L225 WeakPolarHBondContact O-CA 3.34Å; G219-N226 PolarHBondContact N-O 2.93Å; G219-N226 PolarHBondContact O-N 2.69Å
220V98.4Very high97.3Very high0 Ų029.4 Ų29.40%014%0.144CC..EExtended strand (participates in β ladder)trans-114.7120.2170.7-173.10000108.4N204 F206 L218 L225 W242 I280 L283N204-V220 HydrophobicContact CB-CB 4.38Å; N204-V220 PolarHBondContact N-O 2.93Å; N204-V220 PolarHBondContact O-N 3.49Å; F206-V220 HydrophobicContact CD2-CG2 4.02Å; F206-V220 HydrophobicContact CE2-CB 4.47Å; F206-V220 HydrophobicContact CE2-CG2 3.93Å; L218-V220 HydrophobicContact CD2-CG2 4Å; L218-V220 HydrophobicContact CG-CG2 4.08Å; V220-L225 HydrophobicContact CB-CD2 4.19Å; V220-L225 HydrophobicContact CG1-CD2 3.99Å; V220-L225 HydrophobicContact CG2-CD2 3.79Å; V220-W242 HydrophobicContact CG1-CH2 4.08Å; V220-W242 HydrophobicContact CG1-CZ2 3.99Å; V220-I280 HydrophobicContact CG2-CG2 4.42Å; V220-L283 HydrophobicContact CG1-CB 4.1Å
221D97.3Very high97.3Very high6 Ų635.1 Ų35.13%0.03217%0.174CC..  trans-138.2-174-177.769.132.8000112.5I203 L223 G224 N226 W242 N287I203-D221 HydrophobicContact CG1-CB 4.14Å; D221-L223 VanDerWaalsContact C-N 3.27Å; D221-L223 PolarHBondContact O-N 2.91Å; D221-L223 VanDerWaalsContact OD1-CA 3.3Å; D221-L223 WeakPolarHBondContact OD1-CA 3.23Å; D221-L223 WeakPolarHBondContact OD1-CB 3.1Å; D221-L223 PolarHBondContact OD1-N 3.48Å; D221-G224 PolarHBondContact N-O 2.84Å; D221-G224 PolarHBondContact OD1-N 3.48Å; D221-N226 PolarHBondContact OD2-ND2 2.66Å; D221-W242 WeakPolarHBondContact O-CZ2 3.37Å; D221-W242 PolarHBondContact O-NE1 3.11Å; D221-N287 WeakPolarHBondContact O-CB 3.43Å
222A96.5Very high97.4Very high7 Ų730.4 Ų30.46%0.05816%0.155CC..SBendtrans-72.1-16.9-18000000114.1E87E87-A222 HydrophobicContact CG-CB 3.97Å
223L95.2Very high97.5Very high13 Ų1327.1 Ų27.17%0.06814%0.141CC..SBendtrans-103.3-17.7-174.1-58.8170.1000113E87 D221 E514 Y565 L568 R572E87-L223 HydrophobicContact CB-CD2 4.11Å; E87-L223 HydrophobicContact CG-CD2 3.71Å; D221-L223 VanDerWaalsContact C-N 3.27Å; D221-L223 PolarHBondContact O-N 2.91Å; D221-L223 VanDerWaalsContact OD1-CA 3.3Å; D221-L223 WeakPolarHBondContact OD1-CA 3.23Å; D221-L223 WeakPolarHBondContact OD1-CB 3.1Å; D221-L223 PolarHBondContact OD1-N 3.48Å; L223-E514 HydrophobicContact CD2-CB 3.97Å; L223-Y565 HydrophobicContact CD1-CE1 4.47Å; L223-L568 HydrophobicContact CD1-CD1 3.79Å; L223-R572 PolarHBondContact O-NH1 3.06Å; L223-R572 PolarHBondContact O-NH2 3.19Å
224G96.1Very high97.6Very high0 Ų026 Ų260%013%0.127CC..EExtended strand (participates in β ladder)trans159.2-146.317500000114.9D221 F240 W242D221-G224 PolarHBondContact N-O 2.84Å; D221-G224 PolarHBondContact OD1-N 3.48Å; G224-F240 WeakPolarHBondContact CA-O 3.18Å; G224-W242 WeakPolarHBondContact O-CZ2 3.35Å
225L98.3Very high97.6Very high0 Ų024 Ų240%012%0.116CC..EExtended strand (participates in β ladder)trans-117.8129.9172.3-62.1179.9000109.4L218 G219 V220 G239 F240 W242 I245 I257L218-L225 HydrophobicContact CD1-CB 4.27Å; L218-L225 HydrophobicContact CD1-CD2 4.28Å; G219-L225 WeakPolarHBondContact O-CA 3.34Å; V220-L225 HydrophobicContact CB-CD2 4.19Å; V220-L225 HydrophobicContact CG1-CD2 3.99Å; V220-L225 HydrophobicContact CG2-CD2 3.79Å; L225-G239 WeakPolarHBondContact O-CA 3.4Å; L225-F240 HydrophobicContact CB-CB 4.49Å; L225-F240 PolarHBondContact N-O 3.13Å; L225-F240 PolarHBondContact O-N 3.07Å; L225-W242 HydrophobicContact CD1-CH2 4.48Å; L225-W242 HydrophobicContact CD1-CZ3 4.36Å; L225-W242 HydrophobicContact CD2-CH2 3.49Å; L225-W242 VanDerWaalsContact CD2-CH2 3.49Å; L225-W242 HydrophobicContact CD2-CZ2 4.11Å; L225-W242 HydrophobicContact CD2-CZ3 4.16Å; L225-W242 HydrophobicContact CG-CH2 3.8Å; L225-W242 HydrophobicContact CG-CZ2 4.47Å; L225-W242 HydrophobicContact CG-CZ3 4.01Å; L225-I245 HydrophobicContact CD1-CD1 3.71Å; L225-I245 HydrophobicContact CG-CD1 4.06Å; L225-I257 HydrophobicContact CD1-CD1 3.46Å; L225-I257 VanDerWaalsContact CD1-CD1 3.46Å; L225-I257 HydrophobicContact CD1-CG1 4.5Å
226N98.4Very high97.6Very high1 Ų120.3 Ų20.31%0.00510%0.099CC..EExtended strand (participates in β ladder)trans-123.9143.2179-45.8-47.8000109.9G219 D221 Y228 P236 I238G219-N226 PolarHBondContact N-O 2.93Å; G219-N226 PolarHBondContact O-N 2.69Å; D221-N226 PolarHBondContact OD2-ND2 2.66Å; N226-Y228 HydrophobicContact CB-CE2 3.77Å; N226-P236 HydrophobicContact CB-CB 3.87Å; N226-I238 CarbonylContact C-O 3.56Å; N226-I238 WeakPolarHBondContact CA-O 3.45Å
227I98.6Very high97.6Very high0 Ų023.8 Ų23.80%011%0.114CC..EExtended strand (participates in β ladder)trans-110.5137.8177.5-48.1-60.7000110I208 L216 W217 L218 P236 K237 I238 F267 F583I208-I227 HydrophobicContact CD1-CD1 4.21Å; L216-I227 HydrophobicContact CB-CG2 4.22Å; L216-I227 HydrophobicContact CD1-CG2 4.07Å; W217-I227 WeakPolarHBondContact O-CA 3.41Å; L218-I227 HydrophobicContact CD1-CD1 3.62Å; I227-P236 CarbonylContact O-C 3.58Å; I227-P236 WeakPolarHBondContact O-CA 3.44Å; I227-K237 PolarHBondContact O-N 2.93Å; I227-I238 HydrophobicContact CB-CB 4.24Å; I227-I238 HydrophobicContact CG1-CB 4.34Å; I227-I238 PolarHBondContact N-O 3.35Å; I227-F267 HydrophobicContact CD1-CZ 3.8Å; I227-F267 HydrophobicContact CG1-CZ 4.4Å; I227-F583 HydrophobicContact CD1-CD2 4.38Å; I227-F583 HydrophobicContact CD1-CE2 4.22Å; I227-F583 HydrophobicContact CG1-CD2 4.02Å; I227-F583 HydrophobicContact CG1-CE2 4.33Å; I227-F583 HydrophobicContact CG2-CD2 3.94Å; I227-F583 HydrophobicContact CG2-CE2 4.02Å
228Y98.6Very high97.5Very high3 Ų322.4 Ų22.41%0.01211%0.109CC..EExtended strand (participates in β ladder)trans-129.9150.8179-44.1-117.8000110.7I203 Y205 L216 W217 N226 D232 K233 P236I203-Y228 WeakPolarHBondContact CD1-OH 3.16Å; Y205-Y228 HydrophobicContact CD1-CE2 4.45Å; Y205-Y228 HydrophobicContact CE1-CD1 4.41Å; Y205-Y228 HydrophobicContact CE1-CD2 4.26Å; Y205-Y228 HydrophobicContact CE1-CE1 4.08Å; Y205-Y228 AromaticContact CE1-CE2 3.97Å; Y205-Y228 HydrophobicContact CE1-CE2 3.97Å; Y205-Y228 AromaticContact CE1-CZ 3.89Å; L216-Y228 WeakPolarHBondContact CA-O 3.44Å; L216-Y228 WeakPolarHBondContact CD2-O 3.23Å; W217-Y228 HydrophobicContact CB-CD2 4.28Å; W217-Y228 PolarHBondContact N-O 3.01Å; W217-Y228 PolarHBondContact O-N 2.77Å; N226-Y228 HydrophobicContact CB-CE2 3.77Å; Y228-D232 WeakPolarHBondContact CB-O 3.43Å; Y228-K233 WeakPolarHBondContact CE1-O 3.5Å; Y228-P236 HydrophobicContact CD1-CB 3.96Å; Y228-P236 HydrophobicContact CE1-CB 3.66Å; Y228-P236 HydrophobicContact CE1-CG 4.07Å; Y228-P236 HydrophobicContact CE2-CB 4.23Å; Y228-P236 HydrophobicContact CG-CB 4.36Å
229E97.7Very high97.5Very high76 Ų7622.4 Ų22.436%0.35511%0.109SC..EExtended strand (participates in β ladder)trans-66.1158.3167.5-75.8154.5-152.900110.9D231 D232 K237E229-D231 PolarHBondContact O-N 2.81Å; E229-D231 VanDerWaalsContact O-N 3.12Å; E229-D232 PolarHBondContact O-N 3.46Å; E229-D232 VanDerWaalsContact O-O 3.09Å; E229-K237 HydrophobicContact CG-CG 4.36Å; E229-K237 IonicContact OE1-NZ 3.23Å; E229-K237 PolarHBondContact OE1-NZ 3.36Å; E229-K237 IonicContact OE2-NZ 3.13Å; E229-K237 PolarHBondContact OE2-NZ 2.77Å
230K96.3Very high97.4Very high61 Ų6122.7 Ų22.727%0.26511%0.111SC..THydrogen-bonded Turntrans-55.2-35.7-174.3-171.565.5177.6-151.50113.7E207 E215 W217E207-K230 IonicContact OE1-NZ 3.64Å; E207-K230 PolarHBondContact OE1-NZ 3.11Å; E215-K230 HydrophobicContact CB-CB 4.41Å; E215-K230 HydrophobicContact CB-CD 3.9Å; E215-K230 HydrophobicContact CB-CG 4.36Å; E215-K230 IonicContact OE2-NZ 3.05Å; E215-K230 PolarHBondContact OE2-NZ 2.83Å; W217-K230 HydrophobicContact CZ2-CD 4.42Å; W217-K230 PolarHBondContact NE1-O 3.35Å
231D96.6Very high97.3Very high121 Ų12122.7 Ų22.765%0.64711%0.111SC*.THydrogen-bonded Turntrans-99.7-5.5-168.5-55.1-33.3000113.7E229 H549E229-D231 PolarHBondContact O-N 2.81Å; E229-D231 VanDerWaalsContact O-N 3.12Å; D231-H549 PolarHBondContact O-CD2 3.37Å; D231-H549 PolarHBondContact O-NE2 2.98Å
232D97.4Very high97.1Very high18 Ų1822.4 Ų22.410%0.09611%0.109CC..  trans-123.8123.8177.5-174-11.7000110Y228 E229 L234 T235 I553Y228-D232 WeakPolarHBondContact CB-O 3.43Å; E229-D232 PolarHBondContact O-N 3.46Å; E229-D232 VanDerWaalsContact O-O 3.09Å; D232-L234 PolarHBondContact OD1-N 3.25Å; D232-T235 PolarHBondContact OD1-N 2.98Å; D232-T235 PolarHBondContact OD1-OG1 3.46Å; D232-T235 WeakPolarHBondContact OD2-CB 3.39Å; D232-T235 PolarHBondContact OD2-OG1 3.02Å; D232-I553 HydrophobicContact CB-CD1 4.09Å
233K97.4Very high96.9Very high62 Ų6222.9 Ų22.927%0.2711%0.112SC..SBendtrans-111.6-5.9174.7-72.6-177.2177.6176.80113.9M200 Y205 W217 Y228M200-K233 HydrophobicContact CE-CB 4.42Å; M200-K233 HydrophobicContact CE-CD 4.49Å; Y205-K233 HydrophobicContact CD1-CD 4.28Å; Y205-K233 HydrophobicContact CD1-CG 4.2Å; Y205-K233 HydrophobicContact CE1-CB 3.84Å; Y205-K233 HydrophobicContact CE1-CD 4.34Å; Y205-K233 HydrophobicContact CE1-CG 3.98Å; Y205-K233 PolarHBondContact OH-O 3.26Å; W217-K233 VanDerWaalsContact CZ2-NZ 3.29Å; Y228-K233 WeakPolarHBondContact CE1-O 3.5Å
234L97.3Very high96.9Very high4 Ų423.1 Ų23.12%0.02111%0.113CC..SBendtrans-91-42.5178.9-50.8-172.4000110.3Y116 E199 M200 D232 P236 N550 I553 H554Y116-L234 HydrophobicContact CD1-CD1 3.89Å; Y116-L234 HydrophobicContact CD1-CD2 3.93Å; Y116-L234 HydrophobicContact CE1-CD1 4.09Å; Y116-L234 HydrophobicContact CG-CD1 4.36Å; Y116-L234 HydrophobicContact CG-CD2 4.08Å; E199-L234 HydrophobicContact CB-CB 4.06Å; E199-L234 HydrophobicContact CB-CD2 4.25Å; E199-L234 HydrophobicContact CG-CB 4.26Å; M200-L234 HydrophobicContact CG-CD2 3.54Å; M200-L234 HydrophobicContact SD-CD2 3.77Å; D232-L234 PolarHBondContact OD1-N 3.25Å; L234-P236 WeakPolarHBondContact O-CD 3.4Å; L234-N550 HydrophobicContact CD1-CB 4.29Å; L234-N550 WeakPolarHBondContact CD1-O 3.33Å; L234-I553 HydrophobicContact CB-CG2 3.97Å; L234-I553 HydrophobicContact CD1-CB 4.15Å; L234-I553 HydrophobicContact CD1-CG2 4Å; L234-I553 HydrophobicContact CG-CG2 4.25Å; L234-H554 HydrophobicContact CD1-CB 3.88Å
235T97.8Very high96.8Very high7 Ų723.4 Ų23.44%0.04311%0.114CC..SBendtrans-101.395.9-176.1-24.40000111.2D232 K237 N557 T567D232-T235 PolarHBondContact OD1-N 2.98Å; D232-T235 PolarHBondContact OD1-OG1 3.46Å; D232-T235 WeakPolarHBondContact OD2-CB 3.39Å; D232-T235 PolarHBondContact OD2-OG1 3.02Å; T235-K237 WeakPolarHBondContact O-CE 3.49Å; T235-N557 PolarHBondContact OG1-ND2 3.33Å; T235-T567 HydrophobicContact CG2-CG2 4.13Å
236P97.9Very high96.4Very high11 Ų1127.4 Ų27.47%0.07113%0.129CC..  trans-63152.5166.529-35000110.1N226 I227 Y228 L234 T567 I571N226-P236 HydrophobicContact CB-CB 3.87Å; I227-P236 CarbonylContact O-C 3.58Å; I227-P236 WeakPolarHBondContact O-CA 3.44Å; Y228-P236 HydrophobicContact CD1-CB 3.96Å; Y228-P236 HydrophobicContact CE1-CB 3.66Å; Y228-P236 HydrophobicContact CE1-CG 4.07Å; Y228-P236 HydrophobicContact CE2-CB 4.23Å; Y228-P236 HydrophobicContact CG-CB 4.36Å; L234-P236 WeakPolarHBondContact O-CD 3.4Å; P236-T567 HydrophobicContact CG-CG2 4.11Å; P236-I571 HydrophobicContact CB-CD1 3.65Å; P236-I571 HydrophobicContact CG-CD1 3.66Å; P236-I571 WeakPolarHBondContact O-CG2 3.35Å
237K97.4Very high96.2Very high75 Ų7529.1 Ų29.133%0.32614%0.139SC..SBendtrans-108.9-29.7-179.1-51.2-53.917889.10113I227 E229 T235 I571I227-K237 PolarHBondContact O-N 2.93Å; E229-K237 HydrophobicContact CG-CG 4.36Å; E229-K237 IonicContact OE1-NZ 3.23Å; E229-K237 PolarHBondContact OE1-NZ 3.36Å; E229-K237 IonicContact OE2-NZ 3.13Å; E229-K237 PolarHBondContact OE2-NZ 2.77Å; T235-K237 WeakPolarHBondContact O-CE 3.49Å; K237-I571 WeakPolarHBondContact O-CG2 3.36Å
238I97.9Very high96Very high5 Ų529.6 Ų29.63%0.02614%0.141CC..EExtended strand (participates in β ladder)trans-139.1136.8-177.9-54175000108.7N226 I227 F240 R579 E582 F583 L586N226-I238 CarbonylContact C-O 3.56Å; N226-I238 WeakPolarHBondContact CA-O 3.45Å; I227-I238 HydrophobicContact CB-CB 4.24Å; I227-I238 HydrophobicContact CG1-CB 4.34Å; I227-I238 PolarHBondContact N-O 3.35Å; I238-F240 HydrophobicContact CG2-CE2 3.83Å; I238-F240 HydrophobicContact CG2-CZ 3.88Å; I238-R579 HydrophobicContact CG2-CB 3.82Å; I238-R579 HydrophobicContact CG2-CG 4.19Å; I238-R579 WeakPolarHBondContact CG2-O 3.36Å; I238-E582 HydrophobicContact CD1-CB 3.89Å; I238-F583 VanDerWaalsContact CD1-CA 3.43Å; I238-F583 HydrophobicContact CD1-CB 3.77Å; I238-F583 VanDerWaalsContact CD1-N 3.31Å; I238-L586 HydrophobicContact CD1-CD1 4.08Å
239G97.2Very high95.8Very high0 Ų031.5 Ų31.50%016%0.155CC..EExtended strand (participates in β ladder)trans-132.2144.4179.400000114.1L225 I571 R579L225-G239 WeakPolarHBondContact O-CA 3.4Å; G239-I571 PolarHBondContact N-O 3.43Å; G239-R579 WeakPolarHBondContact O-CD 3.37Å; G239-R579 PolarHBondContact O-NH1 3.45Å
240F96.7Very high95.6Very high6 Ų630.5 Ų30.53%0.02615%0.15CC..EExtended strand (participates in β ladder)trans-127.1111.5173.2-57.1-79.3000108.9G224 L225 I238 F267 T576 R579 I580G224-F240 WeakPolarHBondContact CA-O 3.18Å; L225-F240 HydrophobicContact CB-CB 4.49Å; L225-F240 PolarHBondContact N-O 3.13Å; L225-F240 PolarHBondContact O-N 3.07Å; I238-F240 HydrophobicContact CG2-CE2 3.83Å; I238-F240 HydrophobicContact CG2-CZ 3.88Å; F240-F267 HydrophobicContact CD2-CD1 4.49Å; F240-F267 HydrophobicContact CD2-CE1 4.36Å; F240-F267 HydrophobicContact CE2-CD1 4.33Å; F240-F267 HydrophobicContact CE2-CD2 4.35Å; F240-F267 HydrophobicContact CE2-CE1 4.21Å; F240-F267 HydrophobicContact CE2-CE2 4.21Å; F240-F267 HydrophobicContact CE2-CG 4.44Å; F240-F267 HydrophobicContact CE2-CZ 4.17Å; F240-F267 HydrophobicContact CZ-CD2 4.47Å; F240-T576 HydrophobicContact CD1-CG2 4Å; F240-T576 HydrophobicContact CE1-CG2 4Å; F240-R579 HydrophobicContact CE1-CB 3.66Å; F240-R579 HydrophobicContact CZ-CB 3.88Å; F240-I580 HydrophobicContact CE1-CG1 3.88Å; F240-I580 HydrophobicContact CZ-CG1 3.8Å
241P95.8Very high95.5Very high0 Ų034 Ų340%017%0.171CC..EExtended strand (participates in β ladder)trans-66.9155.8174.430.4-35.3000110.6S243 E244P241-S243 PolarHBondContact O-N 3.09Å; P241-E244 HydrophobicContact CG-CB 4.16Å; P241-E244 HydrophobicContact CG-CG 3.82Å; P241-E244 PolarHBondContact O-N 3.19Å
242W95.1Very high95.3Very high0 Ų032.4 Ų32.40%016%0.162CC..G310 helixtrans-58.5-31.7176.5-69.4121.5000112.6V220 D221 G224 L225 E244 I245 I248 C284 N287 H288 Y291V220-W242 HydrophobicContact CG1-CH2 4.08Å; V220-W242 HydrophobicContact CG1-CZ2 3.99Å; D221-W242 WeakPolarHBondContact O-CZ2 3.37Å; D221-W242 PolarHBondContact O-NE1 3.11Å; G224-W242 WeakPolarHBondContact O-CZ2 3.35Å; L225-W242 HydrophobicContact CD1-CH2 4.48Å; L225-W242 HydrophobicContact CD1-CZ3 4.36Å; L225-W242 HydrophobicContact CD2-CH2 3.49Å; L225-W242 VanDerWaalsContact CD2-CH2 3.49Å; L225-W242 HydrophobicContact CD2-CZ2 4.11Å; L225-W242 HydrophobicContact CD2-CZ3 4.16Å; L225-W242 HydrophobicContact CG-CH2 3.8Å; L225-W242 HydrophobicContact CG-CZ2 4.47Å; L225-W242 HydrophobicContact CG-CZ3 4.01Å; W242-E244 PolarHBondContact O-N 3.19Å; W242-E244 VanDerWaalsContact O-N 3.14Å; W242-I245 HydrophobicContact CE3-CD1 3.69Å; W242-I245 HydrophobicContact CZ3-CD1 3.83Å; W242-I245 PolarHBondContact O-N 2.95Å; W242-I245 VanDerWaalsContact O-N 3.09Å; W242-I248 HydrophobicContact CZ3-CD1 3.97Å; W242-C284 HydrophobicContact CH2-CB 3.58Å; W242-C284 HydrophobicContact CZ3-CB 3.87Å; W242-N287 HydrophobicContact CZ2-CB 3.68Å; W242-H288 HydrophobicContact CD2-CB 4.2Å; W242-H288 HydrophobicContact CE3-CB 3.98Å; W242-Y291 HydrophobicContact CB-CD1 3.44Å; W242-Y291 VanDerWaalsContact CB-CD1 3.44Å; W242-Y291 HydrophobicContact CB-CD2 3.79Å; W242-Y291 HydrophobicContact CB-CE1 3.67Å; W242-Y291 HydrophobicContact CB-CE2 3.99Å; W242-Y291 HydrophobicContact CB-CG 3.51Å; W242-Y291 AromaticContact CD1-CD2 3.6Å; W242-Y291 AromaticContact CD1-CG 3.76Å; W242-Y291 HydrophobicContact CG-CD1 4.36Å; W242-Y291 HydrophobicContact CG-CD2 4.1Å; W242-Y291 AromaticContact CG-CG 3.96Å; W242-Y291 HydrophobicContact CG-CG 3.96Å
243S92.2Very high95.1Very high18 Ų1836.6 Ų36.613%0.12618%0.18CC..G310 helixtrans-63.4-8.5173.150.10000115.9P241 I260 Y291P241-S243 PolarHBondContact O-N 3.09Å; S243-I260 WeakPolarHBondContact O-CD1 3.48Å; S243-Y291 WeakPolarHBondContact CB-OH 3.14Å; S243-Y291 PolarHBondContact OG-OH 3.05Å
244E93.7Very high95Very high18 Ų1837.9 Ų37.98%0.08419%0.186CC..G310 helixtrans-99.5-2.7172.9-77.9-179.9-158.300113.6P241 W242 P259 I260 R512 T576 R579P241-E244 HydrophobicContact CG-CB 4.16Å; P241-E244 HydrophobicContact CG-CG 3.82Å; P241-E244 PolarHBondContact O-N 3.19Å; W242-E244 PolarHBondContact O-N 3.19Å; W242-E244 VanDerWaalsContact O-N 3.14Å; E244-P259 CarbonylContact O-C 3.51Å; E244-P259 VanDerWaalsContact O-CA 3.23Å; E244-P259 WeakPolarHBondContact O-CA 3.35Å; E244-I260 PolarHBondContact O-N 3.44Å; E244-R512 IonicContact OE1-NH1 2.74Å; E244-R512 IonicContact OE1-NH2 2.6Å; E244-T576 PolarHBondContact OE2-OG1 2.94Å; E244-R579 IonicContact OE1-CZ 4Å; E244-R579 IonicContact OE1-NH1 2.71Å; E244-R579 IonicContact OE1-NH2 3.29Å; E244-R579 PolarHBondContact OE1-NH2 3.09Å; E244-R579 IonicContact OE2-CZ 2.91Å; E244-R579 IonicContact OE2-NH1 2.71Å; E244-R579 PolarHBondContact OE2-NH1 2.78Å; E244-R579 IonicContact OE2-NH2 3.18Å; E244-R579 PolarHBondContact OE2-NH2 2.7Å; E244-R579 VanDerWaalsContact OE2-NH2 3.12Å
245I93.7Very high95.1Very high5 Ų537.7 Ų37.73%0.02619%0.185CC..EExtended strand (participates in β ladder)trans-109.4123.3-169.3-63.2167.8000111.4L225 W242 I248 I257 L503L225-I245 HydrophobicContact CD1-CD1 3.71Å; L225-I245 HydrophobicContact CG-CD1 4.06Å; W242-I245 HydrophobicContact CE3-CD1 3.69Å; W242-I245 HydrophobicContact CZ3-CD1 3.83Å; W242-I245 PolarHBondContact O-N 2.95Å; W242-I245 VanDerWaalsContact O-N 3.09Å; I245-I248 HydrophobicContact CG2-CD1 3.85Å; I245-I248 HydrophobicContact CG2-CG1 3.68Å; I245-I257 HydrophobicContact CD1-CG2 4.4Å; I245-I257 HydrophobicContact CG1-CG2 4.04Å; I245-I257 HydrophobicContact CG2-CG2 3.82Å; I245-L503 HydrophobicContact CG2-CD1 4.15Å
246R91.4Very high95Very high84 Ų8438.2 Ų38.232%0.31719%0.187SC..EExtended strand (participates in β ladder)trans-94.8-43.8178.7-179.8180-77.2115.6-0.7113.5K258 P259 I260R246-K258 WeakPolarHBondContact CB-O 3.26Å; R246-K258 PolarHBondContact N-O 3.31Å; R246-P259 PolarHBondContact NH1-O 3.44Å; R246-I260 HydrophobicContact CB-CG1 3.97Å; R246-I260 PolarHBondContact NH1-O 2.9Å; R246-I260 PolarHBondContact NH2-O 2.81Å
247N92.9Very high95Very high38 Ų3837.9 Ų37.920%0.20319%0.185CC..EExtended strand (participates in β ladder)trans-150.1142.9-170.2-176-82.3000110.1I257 K258N247-I257 WeakPolarHBondContact O-CA 3.48Å; N247-K258 HydrophobicContact CB-CB 4.13Å; N247-K258 HydrophobicContact CB-CD 4.37Å; N247-K258 HydrophobicContact CB-CG 4.32Å; N247-K258 PolarHBondContact N-O 2.89Å; N247-K258 PolarHBondContact O-N 2.86Å
248I95.2Very high94.9Very high9 Ų938 Ų385%0.04619%0.186CC..EExtended strand (participates in β ladder)trans-131.7124.8-178.3-55.4-177.3000108.5W242 I245 F255 I257 L281 C284 L503W242-I248 HydrophobicContact CZ3-CD1 3.97Å; I245-I248 HydrophobicContact CG2-CD1 3.85Å; I245-I248 HydrophobicContact CG2-CG1 3.68Å; I248-F255 HydrophobicContact CG2-CD1 4.41Å; I248-F255 HydrophobicContact CG2-CE1 3.3Å; I248-F255 HydrophobicContact CG2-CE2 4.47Å; I248-F255 HydrophobicContact CG2-CZ 3.33Å; I248-I257 HydrophobicContact CG1-CG1 4.23Å; I248-I257 HydrophobicContact CG2-CG1 4.1Å; I248-L281 HydrophobicContact CB-CD1 4.03Å; I248-L281 HydrophobicContact CG2-CD1 3.71Å; I248-L281 WeakPolarHBondContact O-CD1 3.41Å; I248-C284 HydrophobicContact CD1-CB 3.45Å; I248-C284 VanDerWaalsContact CD1-CB 3.45Å; I248-L503 HydrophobicContact CD1-CD1 3.63Å; I248-L503 HydrophobicContact CG1-CD1 3.68Å
249S94.1Very high94.7Very high44 Ų4438.2 Ų38.231%0.30819%0.187SC..EExtended strand (participates in β ladder)trans-146.4166.5-177.363.40000111.2V256S249-V256 PolarHBondContact N-O 3Å; S249-V256 PolarHBondContact O-N 2.96Å; S249-V256 VanDerWaalsContact O-O 3.12Å; S249-V256 PolarHBondContact OG-O 3.41Å
250F94.6Very high94.4Very high55 Ų5540.6 Ų40.624%0.24120%0.2CC..EExtended strand (participates in β ladder)trans-148.1156171.165-101.6000111.2K254 F255 L274 N277 K278 L281F250-K254 CarbonylContact C-O 3.54Å; F250-K254 VanDerWaalsContact CA-O 3.23Å; F250-K254 WeakPolarHBondContact CA-O 3.19Å; F250-K254 WeakPolarHBondContact CB-O 3.17Å; F250-F255 HydrophobicContact CB-CD2 3.63Å; F250-F255 HydrophobicContact CB-CE2 4.18Å; F250-F255 HydrophobicContact CB-CG 4.3Å; F250-F255 HydrophobicContact CD1-CD2 4.25Å; F250-F255 AromaticContact CD1-CE2 3.98Å; F250-F255 HydrophobicContact CD1-CE2 3.98Å; F250-F255 HydrophobicContact CG-CD2 4.33Å; F250-L274 HydrophobicContact CD2-CD1 4.04Å; F250-L274 HydrophobicContact CE2-CD1 3.53Å; F250-L274 HydrophobicContact CZ-CD1 4.47Å; F250-N277 HydrophobicContact CB-CB 4.05Å; F250-N277 HydrophobicContact CD1-CB 3.88Å; F250-N277 HydrophobicContact CD2-CB 3.92Å; F250-N277 HydrophobicContact CE1-CB 4.33Å; F250-N277 HydrophobicContact CE2-CB 4.42Å; F250-N277 HydrophobicContact CG-CB 3.67Å; F250-K278 HydrophobicContact CE1-CG 4.18Å; F250-K278 HydrophobicContact CE2-CG 4.23Å; F250-K278 HydrophobicContact CZ-CB 4.48Å; F250-K278 HydrophobicContact CZ-CG 3.5Å; F250-L281 HydrophobicContact CD1-CB 4.09Å; F250-L281 HydrophobicContact CD1-CD2 4.05Å; F250-L281 HydrophobicContact CE1-CB 3.9Å; F250-L281 HydrophobicContact CE1-CD2 3.56Å; F250-L281 HydrophobicContact CE1-CG 4.35Å
251N92.6Very high94.2Very high135 Ų13543.4 Ų43.472%0.72222%0.215SC*.EExtended strand (participates in β ladder)trans-135.4121.6168.1-170.98000109.3K253 K254N251-K253 PolarHBondContact O-N 3.21Å; N251-K254 PolarHBondContact N-O 3.4Å; N251-K254 PolarHBondContact O-N 3.42Å
252D92Very high93.9Very high86 Ų8652 Ų5246%0.4625%0.252SS..THydrogen-bonded Turntrans41.7-107.7-165-17944.4000113N277D252-N277 PolarHBondContact O-ND2 2.84Å
253K94.5Very high93.7Very high106 Ų10660.7 Ų60.746%0.46129%0.29SS..THydrogen-bonded Turntrans-86.8-25.5178.8-71.2171.3-174.9175.50113.9N251 F255 Y270 A271 N277N251-K253 PolarHBondContact O-N 3.21Å; K253-F255 PolarHBondContact O-N 2.94Å; K253-Y270 WeakPolarHBondContact O-CA 3.35Å; K253-A271 WeakPolarHBondContact CB-O 3.48Å; K253-A271 WeakPolarHBondContact CG-O 3.4Å; K253-A271 PolarHBondContact O-N 3.28Å; K253-N277 WeakPolarHBondContact CA-ND2 3.28Å; K253-N277 PolarHBondContact O-ND2 2.95Å
254K95.9Very high93.8Very high90 Ų9060.4 Ų60.439%0.39129%0.289SS..EExtended strand (participates in β ladder)trans-77.5120.1-177.2-173.1-174.2-177.5-173.80110.2F250 N251 V256 V268 Y270F250-K254 CarbonylContact C-O 3.54Å; F250-K254 VanDerWaalsContact CA-O 3.23Å; F250-K254 WeakPolarHBondContact CA-O 3.19Å; F250-K254 WeakPolarHBondContact CB-O 3.17Å; N251-K254 PolarHBondContact N-O 3.4Å; N251-K254 PolarHBondContact O-N 3.42Å; K254-V256 HydrophobicContact CD-CG2 4.23Å; K254-V256 HydrophobicContact CG-CG2 4.14Å; K254-V268 HydrophobicContact CD-CG1 4.35Å; K254-V268 VanDerWaalsContact CE-CG1 3.45Å; K254-V268 HydrophobicContact CG-CG1 3.98Å; K254-Y270 HydrophobicContact CB-CD1 4.06Å; K254-Y270 HydrophobicContact CB-CE1 3.83Å; K254-Y270 HydrophobicContact CD-CE1 4.38Å; K254-Y270 HydrophobicContact CG-CD1 4.35Å; K254-Y270 HydrophobicContact CG-CE1 3.8Å
255F97.9Very high93.9Very high0 Ų062 Ų620%030%0.301CS..EExtended strand (participates in β ladder)trans-99.4143.6171.3-152.6-93.6000109.3I248 F250 K253 I257 V268 F269 N277 I280 L281I248-F255 HydrophobicContact CG2-CD1 4.41Å; I248-F255 HydrophobicContact CG2-CE1 3.3Å; I248-F255 HydrophobicContact CG2-CE2 4.47Å; I248-F255 HydrophobicContact CG2-CZ 3.33Å; F250-F255 HydrophobicContact CB-CD2 3.63Å; F250-F255 HydrophobicContact CB-CE2 4.18Å; F250-F255 HydrophobicContact CB-CG 4.3Å; F250-F255 HydrophobicContact CD1-CD2 4.25Å; F250-F255 AromaticContact CD1-CE2 3.98Å; F250-F255 HydrophobicContact CD1-CE2 3.98Å; F250-F255 HydrophobicContact CG-CD2 4.33Å; K253-F255 PolarHBondContact O-N 2.94Å; F255-I257 HydrophobicContact CD1-CD1 3.93Å; F255-I257 HydrophobicContact CD1-CG1 3.91Å; F255-I257 HydrophobicContact CE1-CD1 3.81Å; F255-I257 HydrophobicContact CE1-CG1 3.73Å; F255-V268 WeakPolarHBondContact O-CA 3.46Å; F255-F269 HydrophobicContact CB-CD1 4.28Å; F255-F269 HydrophobicContact CB-CD2 3.75Å; F255-F269 HydrophobicContact CB-CE1 3.95Å; F255-F269 HydrophobicContact CB-CE2 3.35Å; F255-F269 HydrophobicContact CB-CG 4.19Å; F255-F269 HydrophobicContact CB-CZ 3.46Å; F255-F269 VanDerWaalsContact CB-CZ 3.46Å; F255-F269 HydrophobicContact CD1-CD1 4.35Å; F255-F269 AromaticContact CD1-CE1 3.39Å; F255-F269 HydrophobicContact CD1-CE1 3.39Å; F255-F269 HydrophobicContact CD1-CE2 4.01Å; F255-F269 AromaticContact CD1-CZ 3.17Å; F255-F269 HydrophobicContact CD1-CZ 3.17Å; F255-F269 HydrophobicContact CD2-CE2 4.28Å; F255-F269 HydrophobicContact CD2-CZ 4.07Å; F255-F269 HydrophobicContact CE1-CE1 4.1Å; F255-F269 AromaticContact CE1-CZ 3.81Å; F255-F269 HydrophobicContact CE1-CZ 3.81Å; F255-F269 HydrophobicContact CG-CD2 4.49Å; F255-F269 AromaticContact CG-CE1 3.91Å; F255-F269 HydrophobicContact CG-CE1 3.91Å; F255-F269 AromaticContact CG-CE2 3.66Å; F255-F269 HydrophobicContact CG-CE2 3.66Å; F255-F269 AromaticContact CG-CZ 3.31Å; F255-F269 HydrophobicContact CG-CZ 3.31Å; F255-F269 PolarHBondContact N-O 3.26Å; F255-F269 PolarHBondContact O-N 3.13Å; F255-N277 HydrophobicContact CD2-CB 4.04Å; F255-N277 WeakPolarHBondContact CD2-OD1 3.25Å; F255-N277 HydrophobicContact CE2-CB 4.43Å; F255-I280 HydrophobicContact CD2-CG2 4.49Å; F255-I280 HydrophobicContact CE1-CG2 3.99Å; F255-I280 HydrophobicContact CE2-CB 3.93Å; F255-I280 HydrophobicContact CE2-CG2 3.72Å; F255-I280 HydrophobicContact CZ-CB 4.12Å; F255-I280 HydrophobicContact CZ-CG2 3.42Å; F255-I280 VanDerWaalsContact CZ-CG2 3.42Å; F255-L281 HydrophobicContact CE2-CB 4.29Å; F255-L281 HydrophobicContact CZ-CB 4.42Å
256V97.1Very high94Very high17 Ų1764.6 Ų64.610%0.10332%0.315CS..EExtended strand (participates in β ladder)trans-138.5117.7-175.6-174.60000109.4S249 K254 K258 D266 V268S249-V256 PolarHBondContact N-O 3Å; S249-V256 PolarHBondContact O-N 2.96Å; S249-V256 VanDerWaalsContact O-O 3.12Å; S249-V256 PolarHBondContact OG-O 3.41Å; K254-V256 HydrophobicContact CD-CG2 4.23Å; K254-V256 HydrophobicContact CG-CG2 4.14Å; V256-K258 HydrophobicContact CG1-CG 4.49Å; V256-D266 HydrophobicContact CG1-CB 3.99Å; V256-D266 WeakPolarHBondContact CG1-OD2 3.49Å; V256-V268 HydrophobicContact CG1-CG2 4.31Å; V256-V268 HydrophobicContact CG2-CG2 4.29Å
257I96.9Very high94.3Very high5 Ų560.8 Ų60.83%0.02630%0.3CS..EExtended strand (participates in β ladder)trans-112.1122175.4-68.6154.8000107.5L225 I245 N247 I248 F255 F267 F269L225-I257 HydrophobicContact CD1-CD1 3.46Å; L225-I257 VanDerWaalsContact CD1-CD1 3.46Å; L225-I257 HydrophobicContact CD1-CG1 4.5Å; I245-I257 HydrophobicContact CD1-CG2 4.4Å; I245-I257 HydrophobicContact CG1-CG2 4.04Å; I245-I257 HydrophobicContact CG2-CG2 3.82Å; N247-I257 WeakPolarHBondContact O-CA 3.48Å; I248-I257 HydrophobicContact CG1-CG1 4.23Å; I248-I257 HydrophobicContact CG2-CG1 4.1Å; F255-I257 HydrophobicContact CD1-CD1 3.93Å; F255-I257 HydrophobicContact CD1-CG1 3.91Å; F255-I257 HydrophobicContact CE1-CD1 3.81Å; F255-I257 HydrophobicContact CE1-CG1 3.73Å; I257-F267 HydrophobicContact CB-CB 4.2Å; I257-F267 HydrophobicContact CB-CD1 3.98Å; I257-F267 HydrophobicContact CD1-CD1 3.52Å; I257-F267 HydrophobicContact CD1-CE1 3.74Å; I257-F267 HydrophobicContact CG1-CD1 4.35Å; I257-F267 HydrophobicContact CG2-CD1 4.35Å; I257-F267 PolarHBondContact N-O 3.4Å; I257-F267 PolarHBondContact O-N 3.16Å; I257-F269 HydrophobicContact CD1-CE1 3.82Å
258K95.3Very high94.5Very high77 Ų7759.4 Ų59.434%0.33529%0.293SS..EExtended strand (participates in β ladder)trans-96.6122.3178.6-53.3-167.3161.3-81.40109.1R246 N247 V256 D266R246-K258 WeakPolarHBondContact CB-O 3.26Å; R246-K258 PolarHBondContact N-O 3.31Å; N247-K258 HydrophobicContact CB-CB 4.13Å; N247-K258 HydrophobicContact CB-CD 4.37Å; N247-K258 HydrophobicContact CB-CG 4.32Å; N247-K258 PolarHBondContact N-O 2.89Å; N247-K258 PolarHBondContact O-N 2.86Å; V256-K258 HydrophobicContact CG1-CG 4.49Å; K258-D266 WeakPolarHBondContact CG-OD1 3.43Å; K258-D266 IonicContact NZ-OD1 2.78Å; K258-D266 PolarHBondContact NZ-OD1 2.88Å; K258-D266 IonicContact NZ-OD2 3.4Å; K258-D266 PolarHBondContact NZ-OD2 2.87Å
259P94.3Very high94.7Very high9 Ų959 Ų596%0.05829%0.291CS..EExtended strand (participates in β ladder)trans-69.9165.4177.627.4-33.2000112.6E244 R246 A264 P265 T576E244-P259 CarbonylContact O-C 3.51Å; E244-P259 VanDerWaalsContact O-CA 3.23Å; E244-P259 WeakPolarHBondContact O-CA 3.35Å; R246-P259 PolarHBondContact NH1-O 3.44Å; P259-A264 HydrophobicContact CB-CB 4.29Å; P259-A264 HydrophobicContact CG-CB 3.69Å; P259-P265 WeakPolarHBondContact CD-O 3.19Å; P259-P265 WeakPolarHBondContact CG-O 3.18Å; P259-T576 HydrophobicContact CB-CG2 3.86Å
260I91.2Very high94.9Very high50 Ų5061 Ų6126%0.25629%0.293SS..SBendtrans-70.9-39170.1-65.2-171.2000110.5S243 E244 R246 K262S243-I260 WeakPolarHBondContact O-CD1 3.48Å; E244-I260 PolarHBondContact O-N 3.44Å; R246-I260 HydrophobicContact CB-CG1 3.97Å; R246-I260 PolarHBondContact NH1-O 2.9Å; R246-I260 PolarHBondContact NH2-O 2.81Å; I260-K262 PolarHBondContact O-N 3.26Å
261D90.8Very high94.9Very high66 Ų6658.5 Ų58.535%0.35328%0.282SS..SBendtrans-64.5117.3170.2179.917.4000110.6K263 A264D261-K263 PolarHBondContact O-N 3.49Å; D261-K263 WeakPolarHBondContact OD1-CB 3.46Å; D261-K263 PolarHBondContact OD1-N 3.28Å; D261-A264 HydrophobicContact CB-CB 4.14Å; D261-A264 PolarHBondContact O-N 3.12Å; D261-A264 PolarHBondContact OD2-N 2.65Å
262K90Very high94.9Very high179 Ų17955.1 Ų55.178%0.77827%0.267SS*.THydrogen-bonded Turntrans-73.8-9177.9-64.2-178.4179.7178.80113.2I260I260-K262 PolarHBondContact O-N 3.26Å
263K91.3Very high94.8Very high184 Ų18458.1 Ų58.180%0.827%0.272SS*.THydrogen-bonded Turntrans-92-20.7175.4-57.4175-178.31760112.7D261D261-K263 PolarHBondContact O-N 3.49Å; D261-K263 WeakPolarHBondContact OD1-CB 3.46Å; D261-K263 PolarHBondContact OD1-N 3.28Å
264A93.8Very high94.6Very high11 Ų1156.2 Ų56.29%0.09127%0.267CS..SBendtrans-76.5144.2174.100000110.8P259 D261 T576 K577P259-A264 HydrophobicContact CB-CB 4.29Å; P259-A264 HydrophobicContact CG-CB 3.69Å; D261-A264 HydrophobicContact CB-CB 4.14Å; D261-A264 PolarHBondContact O-N 3.12Å; D261-A264 PolarHBondContact OD2-N 2.65Å; A264-T576 HydrophobicContact CB-CG2 4.44Å; A264-K577 HydrophobicContact CB-CB 4.19Å
265P95.6Very high94.2Very high52 Ų5256 Ų5634%0.33826%0.264SS..PPolyproline II helixtrans-66.9161.9175.829.1-34.9000111.7P259 F267 K577 I580P259-P265 WeakPolarHBondContact CD-O 3.19Å; P259-P265 WeakPolarHBondContact CG-O 3.18Å; P265-F267 PolarHBondContact O-N 2.88Å; P265-K577 HydrophobicContact CG-CG 4.39Å; P265-I580 HydrophobicContact CG-CB 4.23Å; P265-I580 HydrophobicContact CG-CD1 4.15Å; P265-I580 HydrophobicContact CG-CG2 3.9Å; P265-I580 VanDerWaalsContact O-CD1 3.24Å; P265-I580 WeakPolarHBondContact O-CD1 3.18Å
266D96.8Very high93.9Very high60 Ų6058 Ų5832%0.32127%0.274SS..PPolyproline II helixtrans-60.8127.8166.7-78.6-4.3000109.5V256 K258 V268V256-D266 HydrophobicContact CG1-CB 3.99Å; V256-D266 WeakPolarHBondContact CG1-OD2 3.49Å; K258-D266 WeakPolarHBondContact CG-OD1 3.43Å; K258-D266 IonicContact NZ-OD1 2.78Å; K258-D266 PolarHBondContact NZ-OD1 2.88Å; K258-D266 IonicContact NZ-OD2 3.4Å; K258-D266 PolarHBondContact NZ-OD2 2.87Å; D266-V268 HydrophobicContact CB-CG2 4.07Å
267F97.5Very high93.7Very high4 Ų457.2 Ų57.22%0.01827%0.269CS..EExtended strand (participates in β ladder)trans-75.7123169.4174.1-130.1000108.9I227 F240 I257 P265 F269 I580 F583I227-F267 HydrophobicContact CD1-CZ 3.8Å; I227-F267 HydrophobicContact CG1-CZ 4.4Å; F240-F267 HydrophobicContact CD2-CD1 4.49Å; F240-F267 HydrophobicContact CD2-CE1 4.36Å; F240-F267 HydrophobicContact CE2-CD1 4.33Å; F240-F267 HydrophobicContact CE2-CD2 4.35Å; F240-F267 HydrophobicContact CE2-CE1 4.21Å; F240-F267 HydrophobicContact CE2-CE2 4.21Å; F240-F267 HydrophobicContact CE2-CG 4.44Å; F240-F267 HydrophobicContact CE2-CZ 4.17Å; F240-F267 HydrophobicContact CZ-CD2 4.47Å; I257-F267 HydrophobicContact CB-CB 4.2Å; I257-F267 HydrophobicContact CB-CD1 3.98Å; I257-F267 HydrophobicContact CD1-CD1 3.52Å; I257-F267 HydrophobicContact CD1-CE1 3.74Å; I257-F267 HydrophobicContact CG1-CD1 4.35Å; I257-F267 HydrophobicContact CG2-CD1 4.35Å; I257-F267 PolarHBondContact N-O 3.4Å; I257-F267 PolarHBondContact O-N 3.16Å; P265-F267 PolarHBondContact O-N 2.88Å; F267-F269 AromaticContact CE1-CD1 3.93Å; F267-F269 HydrophobicContact CE1-CD1 3.93Å; F267-F269 HydrophobicContact CE1-CE1 4.19Å; F267-F269 AromaticContact CZ-CD1 3.92Å; F267-F269 HydrophobicContact CZ-CD1 3.92Å; F267-I580 HydrophobicContact CB-CD1 3.81Å; F267-I580 HydrophobicContact CB-CG1 3.98Å; F267-I580 HydrophobicContact CD2-CG1 4.22Å; F267-I580 HydrophobicContact CG-CG1 4.41Å; F267-F583 HydrophobicContact CD2-CD1 4.13Å; F267-F583 HydrophobicContact CD2-CE1 4.38Å; F267-F583 HydrophobicContact CD2-CG 4.43Å; F267-F583 HydrophobicContact CE2-CB 4.37Å; F267-F583 AromaticContact CE2-CD1 3.57Å; F267-F583 HydrophobicContact CE2-CD1 3.57Å; F267-F583 AromaticContact CE2-CD2 3.84Å; F267-F583 HydrophobicContact CE2-CD2 3.84Å; F267-F583 AromaticContact CE2-CE1 3.66Å; F267-F583 HydrophobicContact CE2-CE1 3.66Å; F267-F583 AromaticContact CE2-CE2 3.93Å; F267-F583 HydrophobicContact CE2-CE2 3.93Å; F267-F583 AromaticContact CE2-CG 3.65Å; F267-F583 HydrophobicContact CE2-CG 3.65Å; F267-F583 AromaticContact CE2-CZ 3.85Å; F267-F583 HydrophobicContact CE2-CZ 3.85Å; F267-F583 HydrophobicContact CZ-CD2 4.34Å; F267-F583 HydrophobicContact CZ-CE2 4.2Å; F267-F583 HydrophobicContact CZ-CZ 4.3Å
268V97.8Very high93.5Very high8 Ų862.3 Ų62.35%0.04829%0.291CS..EExtended strand (participates in β ladder)trans-135126.6-168173.20000110.5K254 F255 V256 D266 Y270 F583K254-V268 HydrophobicContact CD-CG1 4.35Å; K254-V268 VanDerWaalsContact CE-CG1 3.45Å; K254-V268 HydrophobicContact CG-CG1 3.98Å; F255-V268 WeakPolarHBondContact O-CA 3.46Å; V256-V268 HydrophobicContact CG1-CG2 4.31Å; V256-V268 HydrophobicContact CG2-CG2 4.29Å; D266-V268 HydrophobicContact CB-CG2 4.07Å; V268-Y270 HydrophobicContact CG1-CE2 4.21Å; V268-F583 WeakPolarHBondContact O-CE1 3.35Å
269F98.2Very high93.3Very high0 Ų063.5 Ų63.50%029%0.293CS..EExtended strand (participates in β ladder)trans-137.4171172.365.7-101.4000111.1I208 K209 L218 F255 I257 F267 I280 F583I208-F269 HydrophobicContact CB-CB 4.39Å; I208-F269 HydrophobicContact CB-CD2 3.8Å; I208-F269 HydrophobicContact CB-CE2 4.44Å; I208-F269 HydrophobicContact CB-CG 4.3Å; I208-F269 HydrophobicContact CD1-CB 3.93Å; I208-F269 HydrophobicContact CD1-CD1 4.41Å; I208-F269 HydrophobicContact CD1-CD2 4.28Å; I208-F269 HydrophobicContact CD1-CG 3.97Å; I208-F269 HydrophobicContact CG2-CD2 3.41Å; I208-F269 VanDerWaalsContact CG2-CD2 3.41Å; I208-F269 HydrophobicContact CG2-CE2 3.56Å; I208-F269 HydrophobicContact CG2-CG 4.23Å; I208-F269 HydrophobicContact CG2-CZ 4.44Å; K209-F269 CarbonylContact O-C 3.53Å; K209-F269 WeakPolarHBondContact O-CA 3.45Å; K209-F269 WeakPolarHBondContact O-CB 3.38Å; L218-F269 HydrophobicContact CD2-CE1 3.85Å; L218-F269 HydrophobicContact CD2-CE2 4.17Å; L218-F269 HydrophobicContact CD2-CZ 3.48Å; L218-F269 VanDerWaalsContact CD2-CZ 3.48Å; F255-F269 HydrophobicContact CB-CD1 4.28Å; F255-F269 HydrophobicContact CB-CD2 3.75Å; F255-F269 HydrophobicContact CB-CE1 3.95Å; F255-F269 HydrophobicContact CB-CE2 3.35Å; F255-F269 HydrophobicContact CB-CG 4.19Å; F255-F269 HydrophobicContact CB-CZ 3.46Å; F255-F269 VanDerWaalsContact CB-CZ 3.46Å; F255-F269 HydrophobicContact CD1-CD1 4.35Å; F255-F269 AromaticContact CD1-CE1 3.39Å; F255-F269 HydrophobicContact CD1-CE1 3.39Å; F255-F269 HydrophobicContact CD1-CE2 4.01Å; F255-F269 AromaticContact CD1-CZ 3.17Å; F255-F269 HydrophobicContact CD1-CZ 3.17Å; F255-F269 HydrophobicContact CD2-CE2 4.28Å; F255-F269 HydrophobicContact CD2-CZ 4.07Å; F255-F269 HydrophobicContact CE1-CE1 4.1Å; F255-F269 AromaticContact CE1-CZ 3.81Å; F255-F269 HydrophobicContact CE1-CZ 3.81Å; F255-F269 HydrophobicContact CG-CD2 4.49Å; F255-F269 AromaticContact CG-CE1 3.91Å; F255-F269 HydrophobicContact CG-CE1 3.91Å; F255-F269 AromaticContact CG-CE2 3.66Å; F255-F269 HydrophobicContact CG-CE2 3.66Å; F255-F269 AromaticContact CG-CZ 3.31Å; F255-F269 HydrophobicContact CG-CZ 3.31Å; F255-F269 PolarHBondContact N-O 3.26Å; F255-F269 PolarHBondContact O-N 3.13Å; I257-F269 HydrophobicContact CD1-CE1 3.82Å; F267-F269 AromaticContact CE1-CD1 3.93Å; F267-F269 HydrophobicContact CE1-CD1 3.93Å; F267-F269 HydrophobicContact CE1-CE1 4.19Å; F267-F269 AromaticContact CZ-CD1 3.92Å; F267-F269 HydrophobicContact CZ-CD1 3.92Å; F269-I280 HydrophobicContact CE2-CD1 4.02Å; F269-I280 HydrophobicContact CZ-CD1 4.23Å; F269-I280 HydrophobicContact CZ-CG2 4.39Å; F269-F583 HydrophobicContact CB-CE1 4.46Å; F269-F583 HydrophobicContact CB-CZ 3.9Å
270Y98Very high93.4Very high88 Ų8863 Ų6335%0.34529%0.29SS..EExtended strand (participates in β ladder)trans-123120-178.3-58.7-92.5000110.3I208 K209 K211 K253 K254 V268I208-Y270 CarbonylContact C-O 3.51Å; I208-Y270 WeakPolarHBondContact CA-O 3.35Å; K209-Y270 PolarHBondContact N-O 3.12Å; K209-Y270 PolarHBondContact O-N 3.24Å; K211-Y270 HydrophobicContact CG-CE2 4.27Å; K253-Y270 WeakPolarHBondContact O-CA 3.35Å; K254-Y270 HydrophobicContact CB-CD1 4.06Å; K254-Y270 HydrophobicContact CB-CE1 3.83Å; K254-Y270 HydrophobicContact CD-CE1 4.38Å; K254-Y270 HydrophobicContact CG-CD1 4.35Å; K254-Y270 HydrophobicContact CG-CE1 3.8Å; V268-Y270 HydrophobicContact CG1-CE2 4.21Å
271A96.3Very high93.5Very high2 Ų262.3 Ų62.32%0.01729%0.287CS..  trans-94148.4170.500000110.1K253 R273 I276 N277K253-A271 WeakPolarHBondContact CB-O 3.48Å; K253-A271 WeakPolarHBondContact CG-O 3.4Å; K253-A271 PolarHBondContact O-N 3.28Å; A271-R273 VanDerWaalsContact C-N 3.25Å; A271-R273 PolarHBondContact O-N 2.91Å; A271-R273 VanDerWaalsContact O-N 3.17Å; A271-I276 HydrophobicContact CB-CB 4.27Å; A271-I276 HydrophobicContact CB-CG2 3.97Å; A271-N277 WeakPolarHBondContact CB-OD1 3.44Å
272P92.7Very high93.6Very high64 Ų6462.6 Ų62.642%0.41629%0.286SS..SBendtrans-69.5-17.2-172.123.6-31.7000114.6E207 I276E207-P272 VanDerWaalsContact O-CD 3.27Å; E207-P272 WeakPolarHBondContact O-CD 3.25Å; P272-I276 HydrophobicContact CG-CD1 3.83Å
273R89.9Confident93.8Very high148 Ų14854.1 Ų54.156%0.55825%0.249SC*.SBendtrans-144.5135.9-176.1-54.7-178.9-175.4176.82.4112.1A271 R275 I276 N277A271-R273 VanDerWaalsContact C-N 3.25Å; A271-R273 PolarHBondContact O-N 2.91Å; A271-R273 VanDerWaalsContact O-N 3.17Å; R273-R275 PolarHBondContact O-N 3.02Å; R273-I276 HydrophobicContact CB-CD1 4.04Å; R273-I276 HydrophobicContact CB-CG1 4.31Å; R273-I276 HydrophobicContact CG-CD1 4.32Å; R273-I276 WeakPolarHBondContact O-CB 3.42Å; R273-I276 PolarHBondContact O-N 2.96Å; R273-N277 PolarHBondContact O-N 3.45Å
274L89Confident94.1Very high67 Ų6745.4 Ų45.435%0.35121%0.211SC..Hα-helixtrans-48-34172.8173.662.6000114.4F250 I276 N277 K278F250-L274 HydrophobicContact CD2-CD1 4.04Å; F250-L274 HydrophobicContact CE2-CD1 3.53Å; F250-L274 HydrophobicContact CZ-CD1 4.47Å; L274-I276 VanDerWaalsContact C-N 3.3Å; L274-I276 PolarHBondContact O-N 2.91Å; L274-N277 PolarHBondContact O-N 3.43Å; L274-K278 PolarHBondContact O-N 2.87Å; L274-K278 VanDerWaalsContact O-N 3.09Å
275R87.3Confident94Very high86 Ų8645.8 Ų45.833%0.32521%0.211SC..Hα-helixtrans-60.3-39.1175.2-170.3-163.1-171.1106.316.4112.3D51 T57 R273 K278 R279D51-R275 IonicContact OD2-CZ 3.73Å; D51-R275 IonicContact OD2-NH1 2.65Å; D51-R275 PolarHBondContact OD2-NH1 3.44Å; D51-R275 IonicContact OD2-NH2 2.98Å; D51-R275 PolarHBondContact OD2-NH2 2.8Å; T57-R275 PolarHBondContact OG1-NH2 3.45Å; R273-R275 PolarHBondContact O-N 3.02Å; R275-K278 PolarHBondContact O-N 3.41Å; R275-R279 PolarHBondContact O-N 2.76Å
276I91.3Very high93.9Very high41 Ų4143.7 Ų43.721%0.2120%0.199CC..Hα-helixtrans-68.3-46.8-178.7-64.6166000108.9F206 A271 P272 R273 L274 K278 R279 I280F206-I276 HydrophobicContact CB-CG2 4.4Å; F206-I276 HydrophobicContact CD1-CG2 3.78Å; F206-I276 HydrophobicContact CG-CG2 4.37Å; A271-I276 HydrophobicContact CB-CB 4.27Å; A271-I276 HydrophobicContact CB-CG2 3.97Å; P272-I276 HydrophobicContact CG-CD1 3.83Å; R273-I276 HydrophobicContact CB-CD1 4.04Å; R273-I276 HydrophobicContact CB-CG1 4.31Å; R273-I276 HydrophobicContact CG-CD1 4.32Å; R273-I276 WeakPolarHBondContact O-CB 3.42Å; R273-I276 PolarHBondContact O-N 2.96Å; L274-I276 VanDerWaalsContact C-N 3.3Å; L274-I276 PolarHBondContact O-N 2.91Å; I276-K278 VanDerWaalsContact C-N 3.27Å; I276-K278 PolarHBondContact O-N 3.05Å; I276-R279 CarbonylContact O-C 3.52Å; I276-R279 WeakPolarHBondContact O-CA 3.25Å; I276-R279 PolarHBondContact O-N 3.44Å; I276-I280 HydrophobicContact CG2-CD1 3.74Å; I276-I280 HydrophobicContact CG2-CG1 4.16Å; I276-I280 WeakPolarHBondContact O-CG1 3.2Å; I276-I280 PolarHBondContact O-N 3.47Å
277N93.6Very high93.9Very high0 Ų041 Ų410%019%0.185CC..Hα-helixtrans-56.2-39173.2-74.8-18.1000112.9F250 D252 K253 F255 A271 R273 L274 R279 I280 L281F250-N277 HydrophobicContact CB-CB 4.05Å; F250-N277 HydrophobicContact CD1-CB 3.88Å; F250-N277 HydrophobicContact CD2-CB 3.92Å; F250-N277 HydrophobicContact CE1-CB 4.33Å; F250-N277 HydrophobicContact CE2-CB 4.42Å; F250-N277 HydrophobicContact CG-CB 3.67Å; D252-N277 PolarHBondContact O-ND2 2.84Å; K253-N277 WeakPolarHBondContact CA-ND2 3.28Å; K253-N277 PolarHBondContact O-ND2 2.95Å; F255-N277 HydrophobicContact CD2-CB 4.04Å; F255-N277 WeakPolarHBondContact CD2-OD1 3.25Å; F255-N277 HydrophobicContact CE2-CB 4.43Å; A271-N277 WeakPolarHBondContact CB-OD1 3.44Å; R273-N277 PolarHBondContact O-N 3.45Å; L274-N277 PolarHBondContact O-N 3.43Å; N277-R279 PolarHBondContact O-N 2.96Å; N277-I280 PolarHBondContact O-N 3.17Å; N277-L281 WeakPolarHBondContact O-CB 3.43Å; N277-L281 PolarHBondContact O-N 3.42Å
278K91.9Very high93.7Very high112 Ų11241.1 Ų41.149%0.48719%0.186SC..Hα-helixtrans-63.7-35171.8-75175.1179177.80113.6F250 L274 R275 I276 Q282F250-K278 HydrophobicContact CE1-CG 4.18Å; F250-K278 HydrophobicContact CE2-CG 4.23Å; F250-K278 HydrophobicContact CZ-CB 4.48Å; F250-K278 HydrophobicContact CZ-CG 3.5Å; L274-K278 PolarHBondContact O-N 2.87Å; L274-K278 VanDerWaalsContact O-N 3.09Å; R275-K278 PolarHBondContact O-N 3.41Å; I276-K278 VanDerWaalsContact C-N 3.27Å; I276-K278 PolarHBondContact O-N 3.05Å; K278-Q282 WeakPolarHBondContact O-CB 3.24Å; K278-Q282 WeakPolarHBondContact O-CG 3.4Å; K278-Q282 PolarHBondContact O-N 2.68Å
279R92Very high93.4Very high102 Ų10246.4 Ų46.439%0.38521%0.21SC..Hα-helixtrans-74.5-43.7174.2177.7172.8165-163.4-5.7111.7N204 F206 R275 I276 N277 Q282 L283N204-R279 PolarHBondContact OD1-NH2 2.91Å; F206-R279 HydrophobicContact CE1-CB 4.48Å; F206-R279 HydrophobicContact CE1-CG 3.93Å; F206-R279 HydrophobicContact CZ-CG 3.87Å; R275-R279 PolarHBondContact O-N 2.76Å; I276-R279 CarbonylContact O-C 3.52Å; I276-R279 WeakPolarHBondContact O-CA 3.25Å; I276-R279 PolarHBondContact O-N 3.44Å; N277-R279 PolarHBondContact O-N 2.96Å; R279-Q282 PolarHBondContact O-N 3.28Å; R279-L283 HydrophobicContact CG-CD1 3.89Å; R279-L283 WeakPolarHBondContact O-CG 3.2Å; R279-L283 PolarHBondContact O-N 2.85Å; R279-L283 VanDerWaalsContact O-N 3.11Å
280I95.6Very high93.2Very high0 Ų047 Ų470%021%0.213CC..Hα-helixtrans-57.8-55.5177.1-64.6169.6000109.3F206 L218 V220 F255 F269 I276 N277 Q282 L283 C284F206-I280 HydrophobicContact CB-CD1 4.03Å; F206-I280 HydrophobicContact CB-CG1 4.31Å; F206-I280 HydrophobicContact CD1-CD1 4.42Å; F206-I280 HydrophobicContact CD1-CG1 3.98Å; F206-I280 HydrophobicContact CD2-CD1 4.26Å; F206-I280 HydrophobicContact CD2-CG1 3.66Å; F206-I280 HydrophobicContact CE1-CG1 4.25Å; F206-I280 HydrophobicContact CE2-CG1 3.92Å; F206-I280 HydrophobicContact CG-CD1 3.96Å; F206-I280 HydrophobicContact CG-CG1 3.68Å; F206-I280 HydrophobicContact CZ-CG1 4.23Å; L218-I280 HydrophobicContact CD2-CD1 4.15Å; L218-I280 HydrophobicContact CD2-CG2 3.95Å; V220-I280 HydrophobicContact CG2-CG2 4.42Å; F255-I280 HydrophobicContact CD2-CG2 4.49Å; F255-I280 HydrophobicContact CE1-CG2 3.99Å; F255-I280 HydrophobicContact CE2-CB 3.93Å; F255-I280 HydrophobicContact CE2-CG2 3.72Å; F255-I280 HydrophobicContact CZ-CB 4.12Å; F255-I280 HydrophobicContact CZ-CG2 3.42Å; F255-I280 VanDerWaalsContact CZ-CG2 3.42Å; F269-I280 HydrophobicContact CE2-CD1 4.02Å; F269-I280 HydrophobicContact CZ-CD1 4.23Å; F269-I280 HydrophobicContact CZ-CG2 4.39Å; I276-I280 HydrophobicContact CG2-CD1 3.74Å; I276-I280 HydrophobicContact CG2-CG1 4.16Å; I276-I280 WeakPolarHBondContact O-CG1 3.2Å; I276-I280 PolarHBondContact O-N 3.47Å; N277-I280 PolarHBondContact O-N 3.17Å; I280-Q282 VanDerWaalsContact C-N 3.27Å; I280-Q282 PolarHBondContact O-N 2.71Å; I280-L283 PolarHBondContact O-N 2.93Å; I280-C284 PolarHBondContact O-N 3.12Å; I280-C284 PolarHBondContact O-SG 3.36Å
281L94.8Very high93Very high34 Ų3443 Ų4318%0.17820%0.197CC..Hα-helixtrans-53.4-44.3-179.9179.565.6000112.3I248 F250 F255 N277 L283 C284 M285I248-L281 HydrophobicContact CB-CD1 4.03Å; I248-L281 HydrophobicContact CG2-CD1 3.71Å; I248-L281 WeakPolarHBondContact O-CD1 3.41Å; F250-L281 HydrophobicContact CD1-CB 4.09Å; F250-L281 HydrophobicContact CD1-CD2 4.05Å; F250-L281 HydrophobicContact CE1-CB 3.9Å; F250-L281 HydrophobicContact CE1-CD2 3.56Å; F250-L281 HydrophobicContact CE1-CG 4.35Å; F255-L281 HydrophobicContact CE2-CB 4.29Å; F255-L281 HydrophobicContact CZ-CB 4.42Å; N277-L281 WeakPolarHBondContact O-CB 3.43Å; N277-L281 PolarHBondContact O-N 3.42Å; L281-L283 VanDerWaalsContact C-N 3.27Å; L281-L283 PolarHBondContact O-N 3.36Å; L281-C284 PolarHBondContact O-N 2.97Å; L281-M285 HydrophobicContact CD1-CG 4.11Å; L281-M285 HydrophobicContact CD1-SD 4.09Å; L281-M285 HydrophobicContact CD2-SD 4.35Å; L281-M285 HydrophobicContact CG-CG 4.33Å; L281-M285 HydrophobicContact CG-SD 3.81Å; L281-M285 WeakPolarHBondContact O-CB 3.48Å; L281-M285 WeakPolarHBondContact O-CG 3.25Å; L281-M285 PolarHBondContact O-N 3.29Å
282Q92.1Very high92.6Very high73 Ų7343.5 Ų43.534%0.34120%0.199SC..Hα-helixtrans-73.9-12-179.1-71.2-78.8-80.300114.8K83 K278 R279 I280 M285K83-Q282 PolarHBondContact NZ-O 3.27Å; K278-Q282 WeakPolarHBondContact O-CB 3.24Å; K278-Q282 WeakPolarHBondContact O-CG 3.4Å; K278-Q282 PolarHBondContact O-N 2.68Å; R279-Q282 PolarHBondContact O-N 3.28Å; I280-Q282 VanDerWaalsContact C-N 3.27Å; I280-Q282 PolarHBondContact O-N 2.71Å; Q282-M285 PolarHBondContact NE2-SD 3.24Å; Q282-M285 VanDerWaalsContact NE2-SD 3.45Å
283L94.8Very high92.5Very high1 Ų144.4 Ų44.41%0.00519%0.194CC..Hα-helixtrans-93.8-41.9169-72.5166.7000111K83 F84 N204 F206 V220 R279 I280 L281 G286 N287K83-L283 HydrophobicContact CG-CD2 4.1Å; F84-L283 HydrophobicContact CE1-CD2 4.09Å; N204-L283 HydrophobicContact CB-CD1 3.91Å; N204-L283 WeakPolarHBondContact OD1-CD1 3.34Å; F206-L283 HydrophobicContact CE2-CD1 3.92Å; F206-L283 HydrophobicContact CZ-CD1 3.57Å; V220-L283 HydrophobicContact CG1-CB 4.1Å; R279-L283 HydrophobicContact CG-CD1 3.89Å; R279-L283 WeakPolarHBondContact O-CG 3.2Å; R279-L283 PolarHBondContact O-N 2.85Å; R279-L283 VanDerWaalsContact O-N 3.11Å; I280-L283 PolarHBondContact O-N 2.93Å; L281-L283 VanDerWaalsContact C-N 3.27Å; L281-L283 PolarHBondContact O-N 3.36Å; L283-G286 PolarHBondContact O-N 3.01Å; L283-N287 WeakPolarHBondContact O-CB 3.27Å; L283-N287 PolarHBondContact O-N 3.14Å; L283-N287 PolarHBondContact O-ND2 3.29Å
284C96.3Very high92.5Very high0 Ų040.1 Ų40.10%018%0.178CC..Hα-helixtrans-63.3-43.2176.7-55.80000111.8W242 I248 I280 L281 G286 H288W242-C284 HydrophobicContact CH2-CB 3.58Å; W242-C284 HydrophobicContact CZ3-CB 3.87Å; I248-C284 HydrophobicContact CD1-CB 3.45Å; I248-C284 VanDerWaalsContact CD1-CB 3.45Å; I280-C284 PolarHBondContact O-N 3.12Å; I280-C284 PolarHBondContact O-SG 3.36Å; L281-C284 PolarHBondContact O-N 2.97Å; C284-G286 PolarHBondContact O-N 3.44Å; C284-H288 WeakPolarHBondContact O-CB 3.26Å; C284-H288 PolarHBondContact O-N 2.75Å
285M92.9Very high92.4Very high19 Ų1938.2 Ų38.29%0.09417%0.166CC..Hα-helixtrans-55.1-53.2175.1-77170.153.800111.9L281 Q282 H288 E289 Y499 A501 L503L281-M285 HydrophobicContact CD1-CG 4.11Å; L281-M285 HydrophobicContact CD1-SD 4.09Å; L281-M285 HydrophobicContact CD2-SD 4.35Å; L281-M285 HydrophobicContact CG-CG 4.33Å; L281-M285 HydrophobicContact CG-SD 3.81Å; L281-M285 WeakPolarHBondContact O-CB 3.48Å; L281-M285 WeakPolarHBondContact O-CG 3.25Å; L281-M285 PolarHBondContact O-N 3.29Å; Q282-M285 PolarHBondContact NE2-SD 3.24Å; Q282-M285 VanDerWaalsContact NE2-SD 3.45Å; M285-H288 PolarHBondContact O-N 2.74Å; M285-E289 WeakPolarHBondContact O-CB 3.33Å; M285-E289 PolarHBondContact O-N 2.59Å; M285-Y499 HydrophobicContact CE-CD1 4.29Å; M285-A501 HydrophobicContact CE-CB 3.58Å; M285-A501 HydrophobicContact CG-CB 4.08Å; M285-A501 HydrophobicContact SD-CB 4Å; M285-L503 HydrophobicContact CG-CD2 4.48Å
286G93.5Very high92.4Very high8 Ų838.1 Ų38.18%0.08217%0.168CC..Hα-helixtrans-75.4-33.6-174.900000114.3L283 C284 E289 L290L283-G286 PolarHBondContact O-N 3.01Å; C284-G286 PolarHBondContact O-N 3.44Å; G286-E289 PolarHBondContact O-N 3.09Å; G286-L290 WeakPolarHBondContact O-CG 3.47Å; G286-L290 PolarHBondContact O-N 3.38Å
287N95.9Very high92.2Very high4 Ų441.1 Ų41.12%0.02119%0.19CC..Hα-helixtrans-66.1-41.7171.3-76.3-61.9000111D221 W242 L283 L290 Y291D221-N287 WeakPolarHBondContact O-CB 3.43Å; W242-N287 HydrophobicContact CZ2-CB 3.68Å; L283-N287 WeakPolarHBondContact O-CB 3.27Å; L283-N287 PolarHBondContact O-N 3.14Å; L283-N287 PolarHBondContact O-ND2 3.29Å; N287-L290 PolarHBondContact O-N 2.74Å; N287-Y291 VanDerWaalsContact O-CB 3.24Å; N287-Y291 WeakPolarHBondContact O-CB 3.34Å; N287-Y291 PolarHBondContact O-N 2.86Å
288H93.7Very high92Very high7 Ų744.1 Ų44.13%0.03221%0.206CC..Hα-helixtrans-64.8-41.2174-176.1-73.2000112.2W242 C284 M285 L290 Y291 M292 L503W242-H288 HydrophobicContact CD2-CB 4.2Å; W242-H288 HydrophobicContact CE3-CB 3.98Å; C284-H288 WeakPolarHBondContact O-CB 3.26Å; C284-H288 PolarHBondContact O-N 2.75Å; M285-H288 PolarHBondContact O-N 2.74Å; H288-L290 VanDerWaalsContact C-N 3.34Å; H288-L290 PolarHBondContact O-N 3.17Å; H288-Y291 PolarHBondContact O-N 3.35Å; H288-M292 WeakPolarHBondContact CE1-CG 3.3Å; H288-M292 WeakPolarHBondContact O-CB 3.41Å; H288-M292 VanDerWaalsContact O-CG 3.3Å; H288-M292 WeakPolarHBondContact O-CG 3.31Å; H288-M292 PolarHBondContact O-N 2.87Å; H288-L503 HydrophobicContact CB-CD1 4.26Å; H288-L503 HydrophobicContact CB-CD2 4.27Å
289E91.9Very high92Very high119 Ų11942.3 Ų42.356%0.55621%0.205SC*.Hα-helixtrans-58.6-44.5175.8-172.8178.4171.900111.5M285 G286 R293M285-E289 WeakPolarHBondContact O-CB 3.33Å; M285-E289 PolarHBondContact O-N 2.59Å; G286-E289 PolarHBondContact O-N 3.09Å; E289-R293 WeakPolarHBondContact O-CB 3.42Å; E289-R293 PolarHBondContact O-N 3.37Å
290L93.5Very high92Very high12 Ų1243.6 Ų43.66%0.06322%0.218CC..Hα-helixtrans-69.2-42.3174.9-69.8173.1000113W43 F84 G286 N287 H288 M292 R293 R294W43-L290 HydrophobicContact CB-CD2 4.09Å; W43-L290 HydrophobicContact CG-CD2 4.03Å; F84-L290 HydrophobicContact CB-CD1 3.6Å; F84-L290 HydrophobicContact CD2-CD1 4.33Å; F84-L290 HydrophobicContact CG-CD1 3.98Å; G286-L290 WeakPolarHBondContact O-CG 3.47Å; G286-L290 PolarHBondContact O-N 3.38Å; N287-L290 PolarHBondContact O-N 2.74Å; H288-L290 VanDerWaalsContact C-N 3.34Å; H288-L290 PolarHBondContact O-N 3.17Å; L290-M292 VanDerWaalsContact C-N 3.28Å; L290-M292 PolarHBondContact O-N 3.12Å; L290-R293 WeakPolarHBondContact O-CB 3.21Å; L290-R293 PolarHBondContact O-N 2.77Å; L290-R293 VanDerWaalsContact O-N 3.12Å; L290-R294 WeakPolarHBondContact O-CD 3.34Å; L290-R294 WeakPolarHBondContact O-CG 3.36Å; L290-R294 PolarHBondContact O-N 2.95Å
291Y92.9Very high91.8Very high3 Ų347.9 Ų47.91%0.01224%0.238CC..Hα-helixtrans-57.2-41.4174.6178.3-87.4000112E87 W242 S243 N287 H288 R295 E514E87-Y291 WeakPolarHBondContact OE1-CD2 3.44Å; W242-Y291 HydrophobicContact CB-CD1 3.44Å; W242-Y291 VanDerWaalsContact CB-CD1 3.44Å; W242-Y291 HydrophobicContact CB-CD2 3.79Å; W242-Y291 HydrophobicContact CB-CE1 3.67Å; W242-Y291 HydrophobicContact CB-CE2 3.99Å; W242-Y291 HydrophobicContact CB-CG 3.51Å; W242-Y291 AromaticContact CD1-CD2 3.6Å; W242-Y291 AromaticContact CD1-CG 3.76Å; W242-Y291 HydrophobicContact CG-CD1 4.36Å; W242-Y291 HydrophobicContact CG-CD2 4.1Å; W242-Y291 AromaticContact CG-CG 3.96Å; W242-Y291 HydrophobicContact CG-CG 3.96Å; S243-Y291 WeakPolarHBondContact CB-OH 3.14Å; S243-Y291 PolarHBondContact OG-OH 3.05Å; N287-Y291 VanDerWaalsContact O-CB 3.24Å; N287-Y291 WeakPolarHBondContact O-CB 3.34Å; N287-Y291 PolarHBondContact O-N 2.86Å; H288-Y291 PolarHBondContact O-N 3.35Å; Y291-R295 VanDerWaalsContact CE2-NH2 3.29Å; Y291-R295 VanDerWaalsContact CZ-CZ 3.4Å; Y291-R295 VanDerWaalsContact CZ-NE 3.3Å; Y291-R295 PolarHBondContact O-N 2.9Å; Y291-R295 PolarHBondContact O-NH1 2.87Å; Y291-R295 PolarHBondContact OH-NE 2.84Å; Y291-E514 WeakPolarHBondContact CE2-OE1 3.49Å; Y291-E514 PolarHBondContact OH-OE1 2.6Å
292M89.6Confident91.7Very high13 Ų1346.5 Ų46.56%0.06423%0.231CC..Hα-helixtrans-71.7-34.7174.8-73.8-63.2-58.200113H288 L290 R295 K296 S504 I508H288-M292 WeakPolarHBondContact CE1-CG 3.3Å; H288-M292 WeakPolarHBondContact O-CB 3.41Å; H288-M292 VanDerWaalsContact O-CG 3.3Å; H288-M292 WeakPolarHBondContact O-CG 3.31Å; H288-M292 PolarHBondContact O-N 2.87Å; L290-M292 VanDerWaalsContact C-N 3.28Å; L290-M292 PolarHBondContact O-N 3.12Å; M292-R295 PolarHBondContact O-N 3.11Å; M292-K296 WeakPolarHBondContact O-CG 3.15Å; M292-S504 WeakPolarHBondContact CE-O 3.39Å; M292-I508 HydrophobicContact CE-CD1 4.16Å; M292-I508 HydrophobicContact CE-CG1 3.53Å; M292-I508 HydrophobicContact SD-CD1 3.94Å; M292-I508 HydrophobicContact SD-CG1 3.74Å
293R89.6Confident91.7Very high84 Ų8448 Ų4832%0.31724%0.238SC..Hα-helixtrans-63.3-43.6174.5178.7173.7169.5174.6-8.7111.3W43 E289 L290 R295 K296W43-R293 VanDerWaalsContact CE3-NH1 3.34Å; E289-R293 WeakPolarHBondContact O-CB 3.42Å; E289-R293 PolarHBondContact O-N 3.37Å; L290-R293 WeakPolarHBondContact O-CB 3.21Å; L290-R293 PolarHBondContact O-N 2.77Å; L290-R293 VanDerWaalsContact O-N 3.12Å; R293-R295 VanDerWaalsContact C-N 3.26Å; R293-R295 PolarHBondContact O-N 2.87Å; R293-K296 PolarHBondContact O-N 2.88Å
294R89.4Confident91.7Very high57 Ų5753.4 Ų53.422%0.21526%0.263CS..Hα-helixtrans-64.3-25.3178.3-67.9158.3-175.6141.20.3114.4F85 E87 E92 L290 K296F85-R294 PolarHBondContact O-NH2 2.75Å; E87-R294 WeakPolarHBondContact OE1-CD 3.37Å; E87-R294 IonicContact OE1-CZ 3.61Å; E87-R294 IonicContact OE1-NE 3.44Å; E87-R294 IonicContact OE1-NH1 2.69Å; E87-R294 PolarHBondContact OE1-NH1 2.99Å; E92-R294 IonicContact OE1-CZ 3.84Å; E92-R294 IonicContact OE1-NE 2.75Å; E92-R294 PolarHBondContact OE1-NE 3Å; E92-R294 VanDerWaalsContact OE1-NE 3.1Å; E92-R294 IonicContact OE1-NH2 3.83Å; E92-R294 IonicContact OE2-CZ 2.78Å; E92-R294 IonicContact OE2-NE 3.17Å; E92-R294 PolarHBondContact OE2-NE 3.47Å; E92-R294 IonicContact OE2-NH2 2.76Å; E92-R294 PolarHBondContact OE2-NH2 2.95Å; L290-R294 WeakPolarHBondContact O-CD 3.34Å; L290-R294 WeakPolarHBondContact O-CG 3.36Å; L290-R294 PolarHBondContact O-N 2.95Å; R294-K296 VanDerWaalsContact C-N 3.31Å
295R88.3Confident91.5Very high28 Ų2853.6 Ų53.611%0.10626%0.264CS..THydrogen-bonded Turntrans-93.18.7179.4-73.1160.2-173.573.86.6113E87 Y291 M292 R293 E514E87-R295 IonicContact OE1-CZ 2.6Å; E87-R295 IonicContact OE1-NH1 2.96Å; E87-R295 PolarHBondContact OE1-NH1 2.82Å; E87-R295 IonicContact OE1-NH2 2.68Å; E87-R295 IonicContact OE2-CZ 3.77Å; E87-R295 IonicContact OE2-NH1 3.63Å; E87-R295 PolarHBondContact OE2-NH1 3.46Å; E87-R295 IonicContact OE2-NH2 2.71Å; E87-R295 PolarHBondContact OE2-NH2 3.02Å; Y291-R295 VanDerWaalsContact CE2-NH2 3.29Å; Y291-R295 VanDerWaalsContact CZ-CZ 3.4Å; Y291-R295 VanDerWaalsContact CZ-NE 3.3Å; Y291-R295 PolarHBondContact O-N 2.9Å; Y291-R295 PolarHBondContact O-NH1 2.87Å; Y291-R295 PolarHBondContact OH-NE 2.84Å; M292-R295 PolarHBondContact O-N 3.11Å; R293-R295 VanDerWaalsContact C-N 3.26Å; R293-R295 PolarHBondContact O-N 2.87Å; R295-E514 IonicContact CZ-OE2 3.71Å; R295-E514 IonicContact NE-OE2 3.98Å; R295-E514 IonicContact NH2-OE1 3.18Å; R295-E514 IonicContact NH2-OE2 2.6Å; R295-E514 PolarHBondContact NH2-OE2 3.37Å
296K87.6Confident91.6Very high84 Ų8455.2 Ų55.237%0.36527%0.271SS..SBendtrans-116.7157.4169.7-66.2175.7-176.4-172.80108.7M292 R293 R294 E506M292-K296 WeakPolarHBondContact O-CG 3.15Å; R293-K296 PolarHBondContact O-N 2.88Å; R294-K296 VanDerWaalsContact C-N 3.31Å; K296-E506 WeakPolarHBondContact CE-O 3.31Å; K296-E506 PolarHBondContact NZ-O 3.19Å
297P86.9Confident91.6Very high103 Ų10357 Ų5767%0.66928%0.284SS*.PPolyproline II helixtrans-57.9144.8174.1-23.334.3000111.7T299P297-T299 PolarHBondContact O-N 2.94Å
298D89.1Confident91.4Very high64 Ų6461.1 Ų61.134%0.34230%0.303SS..PPolyproline II helixtrans-52.2137.9174.1-82.7-28.8000110.9V302 Q303 K306D298-V302 HydrophobicContact CB-CB 4.08Å; D298-V302 HydrophobicContact CB-CG1 3.88Å; D298-V302 VanDerWaalsContact CG-CG1 3.45Å; D298-V302 WeakPolarHBondContact OD1-CG1 3.24Å; D298-Q303 HydrophobicContact CB-CG 3.72Å; D298-Q303 PolarHBondContact O-NE2 3.07Å; D298-K306 IonicContact OD1-NZ 3.58Å; D298-K306 WeakPolarHBondContact OD2-CE 3.22Å; D298-K306 IonicContact OD2-NZ 3.12Å; D298-K306 PolarHBondContact OD2-NZ 3.39Å
299T91.1Very high91.2Very high73 Ų7361.9 Ų61.945%0.44831%0.311SS..PPolyproline II helixtrans-66.7159174.262.80000110.7P297 E301 V302 Q303P297-T299 PolarHBondContact O-N 2.94Å; T299-E301 PolarHBondContact O-N 3.16Å; T299-V302 PolarHBondContact O-N 3.22Å; T299-V302 WeakPolarHBondContact OG1-CG2 3.24Å; T299-V302 PolarHBondContact OG1-N 2.82Å; T299-Q303 WeakPolarHBondContact O-CG 3.32Å; T299-Q303 PolarHBondContact O-N 3.28Å
300I92.3Very high91.1Very high130 Ų13064.3 Ų64.367%0.66732%0.315SS*.Hα-helixtrans-52.9-41.2178.9-61.1174000111Q303 Q304I300-Q303 PolarHBondContact O-N 3.19Å; I300-Q304 HydrophobicContact CG2-CG 4.42Å; I300-Q304 WeakPolarHBondContact O-CB 3.39Å; I300-Q304 VanDerWaalsContact O-CG 3.3Å; I300-Q304 WeakPolarHBondContact O-CG 3.37Å; I300-Q304 PolarHBondContact O-N 2.62Å
301E91.1Very high91Very high90 Ų9070.6 Ų70.642%0.42134%0.344SS..Hα-helixtrans-61.4-45.3175.6-166.1-168.3-177.400112.5R40 T299 Q303 Q304 M305R40-E301 IonicContact CZ-OE1 3.4Å; R40-E301 IonicContact NE-OE1 2.61Å; R40-E301 IonicContact NH2-OE1 3.39Å; R40-E301 PolarHBondContact NH2-OE1 3.03Å; T299-E301 PolarHBondContact O-N 3.16Å; E301-Q303 VanDerWaalsContact C-N 3.33Å; E301-Q303 PolarHBondContact O-N 3.38Å; E301-Q304 PolarHBondContact O-N 2.93Å; E301-M305 HydrophobicContact CG-SD 4.23Å; E301-M305 WeakPolarHBondContact O-CB 3.5Å; E301-M305 VanDerWaalsContact O-CG 3.3Å; E301-M305 WeakPolarHBondContact O-CG 3.29Å; E301-M305 PolarHBondContact O-N 2.82Å
302V92.9Very high90.9Very high4 Ų474.5 Ų74.52%0.02436%0.362CS..Hα-helixtrans-65.3-38.8177.7175.40000111W43 I94 D298 T299 M305 K306W43-V302 HydrophobicContact CH2-CG2 4.19Å; I94-V302 HydrophobicContact CD1-CG1 3.98Å; D298-V302 HydrophobicContact CB-CB 4.08Å; D298-V302 HydrophobicContact CB-CG1 3.88Å; D298-V302 VanDerWaalsContact CG-CG1 3.45Å; D298-V302 WeakPolarHBondContact OD1-CG1 3.24Å; T299-V302 PolarHBondContact O-N 3.22Å; T299-V302 WeakPolarHBondContact OG1-CG2 3.24Å; T299-V302 PolarHBondContact OG1-N 2.82Å; V302-M305 PolarHBondContact O-N 2.85Å; V302-K306 HydrophobicContact CG1-CD 4.16Å; V302-K306 HydrophobicContact CG1-CG 4.41Å; V302-K306 WeakPolarHBondContact O-CB 3.32Å; V302-K306 WeakPolarHBondContact O-CG 3.35Å; V302-K306 PolarHBondContact O-N 3.1Å
303Q92.3Very high90.7Very high105 Ų10577.7 Ų77.749%0.49138%0.376SS..Hα-helixtrans-64.1-41.5175.6-65.5-178.131.800111.5D298 T299 I300 E301 K306 A307D298-Q303 HydrophobicContact CB-CG 3.72Å; D298-Q303 PolarHBondContact O-NE2 3.07Å; T299-Q303 WeakPolarHBondContact O-CG 3.32Å; T299-Q303 PolarHBondContact O-N 3.28Å; I300-Q303 PolarHBondContact O-N 3.19Å; E301-Q303 VanDerWaalsContact C-N 3.33Å; E301-Q303 PolarHBondContact O-N 3.38Å; Q303-K306 PolarHBondContact O-N 3.44Å; Q303-A307 WeakPolarHBondContact O-CB 3.46Å; Q303-A307 PolarHBondContact O-N 3.4Å
304Q94Very high90.7Very high115 Ų11579 Ų7954%0.53739%0.385SS..Hα-helixtrans-63.7-46.6173.4-74.6170.5-24.300111.6I300 E301 K306 A307 Q308I300-Q304 HydrophobicContact CG2-CG 4.42Å; I300-Q304 WeakPolarHBondContact O-CB 3.39Å; I300-Q304 VanDerWaalsContact O-CG 3.3Å; I300-Q304 WeakPolarHBondContact O-CG 3.37Å; I300-Q304 PolarHBondContact O-N 2.62Å; E301-Q304 PolarHBondContact O-N 2.93Å; Q304-K306 PolarHBondContact O-N 2.88Å; Q304-A307 WeakPolarHBondContact O-CB 3.29Å; Q304-A307 PolarHBondContact O-N 3.35Å; Q304-A307 VanDerWaalsContact O-N 3.14Å; Q304-Q308 WeakPolarHBondContact O-CB 3.02Å; Q304-Q308 PolarHBondContact O-N 2.97Å
305M93.3Very high90.8Very high4 Ų481.8 Ų81.82%0.0240%0.401CS..Hα-helixtrans-59.5-44.2175.4-71.8172.459.100111.7R40 E41 W43 I94 Q95 E301 V302 A307 A309R40-M305 HydrophobicContact CB-CE 3.61Å; R40-M305 HydrophobicContact CB-SD 3.97Å; R40-M305 VanDerWaalsContact CZ-CG 3.48Å; E41-M305 HydrophobicContact CG-CE 3.54Å; W43-M305 HydrophobicContact CH2-CE 4.13Å; W43-M305 HydrophobicContact CH2-SD 4.4Å; I94-M305 HydrophobicContact CD1-CB 4.38Å; I94-M305 HydrophobicContact CD1-CE 4.22Å; I94-M305 HydrophobicContact CG2-CB 4Å; I94-M305 WeakPolarHBondContact CG2-O 3.33Å; Q95-M305 HydrophobicContact CG-CE 4.45Å; E301-M305 HydrophobicContact CG-SD 4.23Å; E301-M305 WeakPolarHBondContact O-CB 3.5Å; E301-M305 VanDerWaalsContact O-CG 3.3Å; E301-M305 WeakPolarHBondContact O-CG 3.29Å; E301-M305 PolarHBondContact O-N 2.82Å; V302-M305 PolarHBondContact O-N 2.85Å; M305-A307 VanDerWaalsContact C-N 3.34Å; M305-A307 PolarHBondContact O-N 3.07Å; M305-A309 VanDerWaalsContact O-CB 3.29Å; M305-A309 WeakPolarHBondContact O-CB 3.4Å; M305-A309 PolarHBondContact O-N 3Å
306K93.7Very high90.7Very high53 Ų5384.5 Ų84.523%0.2341%0.413CS..Hα-helixtrans-67.6-30.5175.2-74.5-178.7177.9178.40112.4E91 I94 D298 V302 Q303 Q304 R310E91-K306 PolarHBondContact O-NZ 2.93Å; I94-K306 HydrophobicContact CD1-CG 3.9Å; I94-K306 HydrophobicContact CG1-CG 3.94Å; I94-K306 HydrophobicContact CG2-CG 4.12Å; D298-K306 IonicContact OD1-NZ 3.58Å; D298-K306 WeakPolarHBondContact OD2-CE 3.22Å; D298-K306 IonicContact OD2-NZ 3.12Å; D298-K306 PolarHBondContact OD2-NZ 3.39Å; V302-K306 HydrophobicContact CG1-CD 4.16Å; V302-K306 HydrophobicContact CG1-CG 4.41Å; V302-K306 WeakPolarHBondContact O-CB 3.32Å; V302-K306 WeakPolarHBondContact O-CG 3.35Å; V302-K306 PolarHBondContact O-N 3.1Å; Q303-K306 PolarHBondContact O-N 3.44Å; Q304-K306 PolarHBondContact O-N 2.88Å; K306-R310 WeakPolarHBondContact O-CB 3.47Å; K306-R310 VanDerWaalsContact O-CG 3.3Å; K306-R310 WeakPolarHBondContact O-CG 3.47Å; K306-R310 PolarHBondContact O-N 3.02Å; K306-R310 PolarHBondContact O-NE 3.33Å
307A93.5Very high90.7Very high45 Ų4585.2 Ų85.237%0.37242%0.418SS..Hα-helixtrans-68.4-55.8172.400000110.6Q303 Q304 M305 A309 R310 E311Q303-A307 WeakPolarHBondContact O-CB 3.46Å; Q303-A307 PolarHBondContact O-N 3.4Å; Q304-A307 WeakPolarHBondContact O-CB 3.29Å; Q304-A307 PolarHBondContact O-N 3.35Å; Q304-A307 VanDerWaalsContact O-N 3.14Å; M305-A307 VanDerWaalsContact C-N 3.34Å; M305-A307 PolarHBondContact O-N 3.07Å; A307-A309 PolarHBondContact O-N 3.07Å; A307-R310 PolarHBondContact O-N 3Å; A307-R310 VanDerWaalsContact O-N 3.09Å; A307-E311 PolarHBondContact O-N 3.49Å
308Q92.7Very high90.8Very high90 Ų9083 Ų8342%0.42140%0.4SS..Hα-helixtrans-52.8-50.7177.7-179.7-178.5-4.900112Q304 R310 E311 E312Q304-Q308 WeakPolarHBondContact O-CB 3.02Å; Q304-Q308 PolarHBondContact O-N 2.97Å; Q308-R310 VanDerWaalsContact C-N 3.3Å; Q308-R310 PolarHBondContact O-N 3.44Å; Q308-E311 PolarHBondContact O-N 3.28Å; Q308-E311 VanDerWaalsContact O-N 3.14Å; Q308-E312 HydrophobicContact CG-CG 4.37Å; Q308-E312 VanDerWaalsContact CG-OE1 3.25Å; Q308-E312 WeakPolarHBondContact CG-OE1 3.45Å; Q308-E312 PolarHBondContact NE2-OE1 3.39Å; Q308-E312 WeakPolarHBondContact O-CB 3.31Å; Q308-E312 WeakPolarHBondContact O-CG 3.46Å; Q308-E312 PolarHBondContact O-N 2.88Å
309A90.3Very high90.8Very high23 Ų2386 Ų8619%0.1941%0.413CS..Hα-helixtrans-64.2-31.7-179.700000113.4I94 M305 A307 K313I94-A309 HydrophobicContact CG2-CB 3.74Å; I94-A309 VanDerWaalsContact O-CB 3.24Å; I94-A309 WeakPolarHBondContact O-CB 3.35Å; M305-A309 VanDerWaalsContact O-CB 3.29Å; M305-A309 WeakPolarHBondContact O-CB 3.4Å; M305-A309 PolarHBondContact O-N 3Å; A307-A309 PolarHBondContact O-N 3.07Å; A309-K313 WeakPolarHBondContact O-CB 3.46Å; A309-K313 PolarHBondContact O-N 3.03Å
310R89.9Confident90.5Very high170 Ų17086.1 Ų86.164%0.64241%0.405SS*.Hα-helixtrans-72.6-37.9173.4-77177.9-66.1-173.61.6111.9K306 A307 Q308 H314K306-R310 WeakPolarHBondContact O-CB 3.47Å; K306-R310 VanDerWaalsContact O-CG 3.3Å; K306-R310 WeakPolarHBondContact O-CG 3.47Å; K306-R310 PolarHBondContact O-N 3.02Å; K306-R310 PolarHBondContact O-NE 3.33Å; A307-R310 PolarHBondContact O-N 3Å; A307-R310 VanDerWaalsContact O-N 3.09Å; Q308-R310 VanDerWaalsContact C-N 3.3Å; Q308-R310 PolarHBondContact O-N 3.44Å; R310-H314 VanDerWaalsContact O-CB 3.23Å; R310-H314 WeakPolarHBondContact O-CB 3.33Å; R310-H314 PolarHBondContact O-N 3.29Å
311E91.6Very high90.3Very high145 Ų14584.7 Ų84.768%0.67840%0.395SS*.Hα-helixtrans-66.7-49.1175.9-174.1166.4-159.100111.4A307 Q308 K313 H314 Q315A307-E311 PolarHBondContact O-N 3.49Å; Q308-E311 PolarHBondContact O-N 3.28Å; Q308-E311 VanDerWaalsContact O-N 3.14Å; E311-K313 VanDerWaalsContact C-N 3.34Å; E311-K313 PolarHBondContact O-N 3.49Å; E311-H314 PolarHBondContact O-N 3.36Å; E311-Q315 WeakPolarHBondContact O-CB 3.49Å; E311-Q315 PolarHBondContact O-N 3.26Å
312E89.2Confident90.2Very high84 Ų8486.8 Ų86.839%0.39341%0.405SS..Hα-helixtrans-57.6-44.1173.4-71.9176-16700111.8Q308 Q315 K316Q308-E312 HydrophobicContact CG-CG 4.37Å; Q308-E312 VanDerWaalsContact CG-OE1 3.25Å; Q308-E312 WeakPolarHBondContact CG-OE1 3.45Å; Q308-E312 PolarHBondContact NE2-OE1 3.39Å; Q308-E312 WeakPolarHBondContact O-CB 3.31Å; Q308-E312 WeakPolarHBondContact O-CG 3.46Å; Q308-E312 PolarHBondContact O-N 2.88Å; E312-Q315 PolarHBondContact O-N 2.87Å; E312-K316 WeakPolarHBondContact O-CB 3.46Å; E312-K316 VanDerWaalsContact O-CG 3.27Å; E312-K316 WeakPolarHBondContact O-CG 3.31Å; E312-K316 PolarHBondContact O-N 3.45Å
313K86.6Confident90Very high81 Ų8192.6 Ų92.635%0.35244%0.435SS..Hα-helixtrans-66.7-38.8177.7-171.9164.6-170.8159.80112.6N186 A309 E311 Q317N186-K313 VanDerWaalsContact OD1-CE 3.31Å; N186-K313 WeakPolarHBondContact OD1-CE 3.49Å; N186-K313 PolarHBondContact OD1-NZ 3.07Å; A309-K313 WeakPolarHBondContact O-CB 3.46Å; A309-K313 PolarHBondContact O-N 3.03Å; E311-K313 VanDerWaalsContact C-N 3.34Å; E311-K313 PolarHBondContact O-N 3.49Å; K313-Q317 WeakPolarHBondContact O-CB 3.32Å; K313-Q317 PolarHBondContact O-N 3.36Å; K313-Q317 VanDerWaalsContact O-N 3.11Å
314H89.4Confident89.7Confident110 Ų11090.9 Ų90.951%0.50943%0.427SS..Hα-helixtrans-66.7-42.3174.5-178.2-110.2000111.5R310 E311 Q317 L318R310-H314 VanDerWaalsContact O-CB 3.23Å; R310-H314 WeakPolarHBondContact O-CB 3.33Å; R310-H314 PolarHBondContact O-N 3.29Å; E311-H314 PolarHBondContact O-N 3.36Å; H314-Q317 WeakPolarHBondContact O-CB 3.41Å; H314-Q317 PolarHBondContact O-N 3.11Å; H314-Q317 VanDerWaalsContact O-N 3.14Å; H314-L318 PolarHBondContact O-N 3.34Å
315Q90.6Very high89.6Confident117 Ų11789.9 Ų89.955%0.54743%0.429SS..Hα-helixtrans-63.7-47177.6-173631000111.7E311 E312 Q317 L318 E319E311-Q315 WeakPolarHBondContact O-CB 3.49Å; E311-Q315 PolarHBondContact O-N 3.26Å; E312-Q315 PolarHBondContact O-N 2.87Å; Q315-Q317 PolarHBondContact O-N 3.34Å; Q315-L318 PolarHBondContact O-N 3.14Å; Q315-E319 WeakPolarHBondContact O-CB 3.32Å; Q315-E319 PolarHBondContact O-N 3.48Å
316K87.2Confident89.4Confident84 Ų8493.2 Ų93.237%0.36544%0.444SS..Hα-helixtrans-55.7-36.8171.6-72.2172-177.9-174.10112.3D96 E312 R320D96-K316 IonicContact OD2-NZ 2.8Å; D96-K316 PolarHBondContact OD2-NZ 2.95Å; E312-K316 WeakPolarHBondContact O-CB 3.46Å; E312-K316 VanDerWaalsContact O-CG 3.27Å; E312-K316 WeakPolarHBondContact O-CG 3.31Å; E312-K316 PolarHBondContact O-N 3.45Å; K316-R320 WeakPolarHBondContact O-CB 3.46Å; K316-R320 PolarHBondContact O-N 3.25Å; K316-R320 VanDerWaalsContact O-N 3.11Å
317Q86.4Confident89.1Confident99 Ų9996.6 Ų96.646%0.46346%0.459SS..Hα-helixtrans-71.9-41.4178-176.9171.9-12.700112.2K313 H314 Q315 Q321K313-Q317 WeakPolarHBondContact O-CB 3.32Å; K313-Q317 PolarHBondContact O-N 3.36Å; K313-Q317 VanDerWaalsContact O-N 3.11Å; H314-Q317 WeakPolarHBondContact O-CB 3.41Å; H314-Q317 PolarHBondContact O-N 3.11Å; H314-Q317 VanDerWaalsContact O-N 3.14Å; Q315-Q317 PolarHBondContact O-N 3.34Å; Q317-Q321 WeakPolarHBondContact O-CB 3.48Å; Q317-Q321 VanDerWaalsContact O-CG 3.31Å; Q317-Q321 WeakPolarHBondContact O-CG 3.45Å; Q317-Q321 PolarHBondContact O-N 3.09Å
318L89.9Confident88.9Confident57 Ų57100.3 Ų100.330%0.29847%0.467SS..Hα-helixtrans-64.4-47.7174.6-73.1176.4000111.9H314 Q315 R320 Q321 Q322H314-L318 PolarHBondContact O-N 3.34Å; Q315-L318 PolarHBondContact O-N 3.14Å; L318-R320 VanDerWaalsContact C-N 3.31Å; L318-R320 PolarHBondContact O-N 3.14Å; L318-Q321 PolarHBondContact O-N 3.32Å; L318-Q321 VanDerWaalsContact O-N 3.11Å; L318-Q322 WeakPolarHBondContact O-CG 3.39Å; L318-Q322 PolarHBondContact O-N 3.47Å
319E89.3Confident88.8Confident128 Ų128104.1 Ų104.160%0.59848%0.478SS*.Hα-helixtrans-55.8-46.7176.2-175.2-172.3177.300110.8Q315 Q321 Q322 L323Q315-E319 WeakPolarHBondContact O-CB 3.32Å; Q315-E319 PolarHBondContact O-N 3.48Å; E319-Q321 PolarHBondContact O-N 3.42Å; E319-Q322 PolarHBondContact O-N 2.81Å; E319-L323 WeakPolarHBondContact O-CB 3.39Å; E319-L323 PolarHBondContact O-N 2.8Å
320R84.1Confident88.7Confident74 Ų74110.9 Ų110.928%0.27950%0.498SS..Hα-helixtrans-63.9-40175.5179.9175.9163-161-12.6112.8G181 K316 L318 Q322 L323 E324G181-R320 PolarHBondContact O-NH1 3.45Å; G181-R320 PolarHBondContact O-NH2 3.13Å; G181-R320 VanDerWaalsContact O-NH2 3.16Å; K316-R320 WeakPolarHBondContact O-CB 3.46Å; K316-R320 PolarHBondContact O-N 3.25Å; K316-R320 VanDerWaalsContact O-N 3.11Å; L318-R320 VanDerWaalsContact C-N 3.31Å; L318-R320 PolarHBondContact O-N 3.14Å; R320-Q322 VanDerWaalsContact C-N 3.32Å; R320-Q322 PolarHBondContact O-N 3.06Å; R320-L323 PolarHBondContact O-N 2.94Å; R320-E324 HydrophobicContact CG-CG 4.39Å; R320-E324 IonicContact CZ-OE1 2.68Å; R320-E324 IonicContact NE-OE1 2.75Å; R320-E324 PolarHBondContact NE-OE1 3.07Å; R320-E324 IonicContact NH2-OE1 2.66Å; R320-E324 PolarHBondContact NH2-OE1 3.09Å; R320-E324 WeakPolarHBondContact O-CB 3.43Å; R320-E324 WeakPolarHBondContact O-CG 3.45Å; R320-E324 PolarHBondContact O-N 2.99Å
321Q88.1Confident88.7Confident100 Ų100105.9 Ų105.947%0.46748%0.482SS..Hα-helixtrans-64.4-37.4176.4-77.3176-2.600111.9Q317 L318 E319 T325Q317-Q321 WeakPolarHBondContact O-CB 3.48Å; Q317-Q321 VanDerWaalsContact O-CG 3.31Å; Q317-Q321 WeakPolarHBondContact O-CG 3.45Å; Q317-Q321 PolarHBondContact O-N 3.09Å; L318-Q321 PolarHBondContact O-N 3.32Å; L318-Q321 VanDerWaalsContact O-N 3.11Å; E319-Q321 PolarHBondContact O-N 3.42Å; Q321-T325 WeakPolarHBondContact O-CB 3.27Å; Q321-T325 PolarHBondContact O-N 3.03Å; Q321-T325 PolarHBondContact O-OG1 2.88Å
322Q90.5Very high88.7Confident134 Ų134102.1 Ų102.163%0.62647%0.469SS*.Hα-helixtrans-64.4-48172.2-67.8172.114.500110.8L318 E319 R320 E324 T325 E326L318-Q322 WeakPolarHBondContact O-CG 3.39Å; L318-Q322 PolarHBondContact O-N 3.47Å; E319-Q322 PolarHBondContact O-N 2.81Å; R320-Q322 VanDerWaalsContact C-N 3.32Å; R320-Q322 PolarHBondContact O-N 3.06Å; Q322-E324 PolarHBondContact O-N 2.73Å; Q322-T325 PolarHBondContact O-N 3.46Å; Q322-E326 WeakPolarHBondContact O-CB 3.39Å; Q322-E326 PolarHBondContact O-N 3.44Å
323L88.1Confident88.9Confident126 Ų126102 Ų10266%0.6647%0.474SS*.Hα-helixtrans-58.8-44.8177-168.886000112.4E319 R320 T325 K327E319-L323 WeakPolarHBondContact O-CB 3.39Å; E319-L323 PolarHBondContact O-N 2.8Å; R320-L323 PolarHBondContact O-N 2.94Å; L323-T325 VanDerWaalsContact C-N 3.33Å; L323-T325 PolarHBondContact O-N 2.97Å; L323-K327 VanDerWaalsContact O-CB 3.26Å; L323-K327 WeakPolarHBondContact O-CB 3.39Å; L323-K327 PolarHBondContact O-N 3.08Å
324E86.4Confident89Confident70 Ų70104.1 Ų104.133%0.32749%0.485SS..Hα-helixtrans-67-33.5177.1-76.8-173.4-163.100112.6R320 Q322 K328R320-E324 HydrophobicContact CG-CG 4.39Å; R320-E324 IonicContact CZ-OE1 2.68Å; R320-E324 IonicContact NE-OE1 2.75Å; R320-E324 PolarHBondContact NE-OE1 3.07Å; R320-E324 IonicContact NH2-OE1 2.66Å; R320-E324 PolarHBondContact NH2-OE1 3.09Å; R320-E324 WeakPolarHBondContact O-CB 3.43Å; R320-E324 WeakPolarHBondContact O-CG 3.45Å; R320-E324 PolarHBondContact O-N 2.99Å; Q322-E324 PolarHBondContact O-N 2.73Å; E324-K328 WeakPolarHBondContact O-CB 3.35Å; E324-K328 WeakPolarHBondContact O-CD 3.37Å; E324-K328 VanDerWaalsContact O-CG 3.26Å; E324-K328 WeakPolarHBondContact O-CG 3.34Å; E324-K328 PolarHBondContact O-N 2.75Å
325T90.3Very high89.1Confident93 Ų93106.6 Ų106.657%0.57149%0.49SS*.Hα-helixtrans-71.7-44.7176.8-58.40000111.1Q321 Q322 L323 K328 R329Q321-T325 WeakPolarHBondContact O-CB 3.27Å; Q321-T325 PolarHBondContact O-N 3.03Å; Q321-T325 PolarHBondContact O-OG1 2.88Å; Q322-T325 PolarHBondContact O-N 3.46Å; L323-T325 VanDerWaalsContact C-N 3.33Å; L323-T325 PolarHBondContact O-N 2.97Å; T325-K328 PolarHBondContact O-N 3.25Å; T325-R329 WeakPolarHBondContact O-CB 2.92Å; T325-R329 PolarHBondContact O-N 3.44Å
326E89.6Confident89.2Confident74 Ų74106.2 Ų106.235%0.34649%0.488SS..Hα-helixtrans-63-40.3173.7174.761.2-175.300111.5Q322 R329 R330Q322-E326 WeakPolarHBondContact O-CB 3.39Å; Q322-E326 PolarHBondContact O-N 3.44Å; E326-R329 WeakPolarHBondContact O-CB 3.48Å; E326-R329 PolarHBondContact O-N 2.9Å; E326-R330 WeakPolarHBondContact O-CG 3.37Å; E326-R330 PolarHBondContact O-N 3.23Å; E326-R330 IonicContact OE1-CZ 3.12Å; E326-R330 IonicContact OE1-NE 2.75Å; E326-R330 PolarHBondContact OE1-NE 2.71Å; E326-R330 IonicContact OE1-NH2 2.7Å; E326-R330 PolarHBondContact OE1-NH2 3.1Å
327K88.3Confident89.4Confident124 Ų124108.7 Ų108.754%0.53950%0.499SS..Hα-helixtrans-61.5-46.9174.5-170.8174.9-170.1-69.40111.7L323 R329 R330 E331L323-K327 VanDerWaalsContact O-CB 3.26Å; L323-K327 WeakPolarHBondContact O-CB 3.39Å; L323-K327 PolarHBondContact O-N 3.08Å; K327-R329 VanDerWaalsContact C-N 3.31Å; K327-R329 PolarHBondContact O-N 2.73Å; K327-R330 PolarHBondContact O-N 2.66Å; K327-E331 IonicContact NZ-OE1 2.66Å; K327-E331 PolarHBondContact NZ-OE1 2.95Å; K327-E331 WeakPolarHBondContact O-CG 3.3Å; K327-E331 PolarHBondContact O-N 3.26Å
328K88.7Confident89.7Confident124 Ų124108.7 Ų108.754%0.53950%0.499SS..Hα-helixtrans-59.6-40.7174-74.4164.4-174.7162.90111.9E324 T325 E331 T332E324-K328 WeakPolarHBondContact O-CB 3.35Å; E324-K328 WeakPolarHBondContact O-CD 3.37Å; E324-K328 VanDerWaalsContact O-CG 3.26Å; E324-K328 WeakPolarHBondContact O-CG 3.34Å; E324-K328 PolarHBondContact O-N 2.75Å; T325-K328 PolarHBondContact O-N 3.25Å; K328-E331 PolarHBondContact O-N 2.89Å; K328-T332 PolarHBondContact O-N 2.74Å; K328-T332 PolarHBondContact O-OG1 2.9Å
329R90.4Very high89.9Confident170 Ų170111.5 Ų111.564%0.64251%0.51SS*.Hα-helixtrans-64.9-37.8177.4-169-178.3-172179.63.7112.7T325 E326 K327 T332 V333T325-R329 WeakPolarHBondContact O-CB 2.92Å; T325-R329 PolarHBondContact O-N 3.44Å; E326-R329 WeakPolarHBondContact O-CB 3.48Å; E326-R329 PolarHBondContact O-N 2.9Å; K327-R329 VanDerWaalsContact C-N 3.31Å; K327-R329 PolarHBondContact O-N 2.73Å; R329-T332 PolarHBondContact O-OG1 3.28Å; R329-V333 WeakPolarHBondContact O-CG2 3.37Å; R329-V333 PolarHBondContact O-N 2.89Å; R329-V333 VanDerWaalsContact O-N 3.09Å
330R89Confident90Very high164 Ų164111 Ų11162%0.61951%0.51SS*.Hα-helixtrans-66.8-45.1172.4-69.5177.4-170.5-161.43.1111.2E326 K327 T332 V333 E334E326-R330 WeakPolarHBondContact O-CG 3.37Å; E326-R330 PolarHBondContact O-N 3.23Å; E326-R330 IonicContact OE1-CZ 3.12Å; E326-R330 IonicContact OE1-NE 2.75Å; E326-R330 PolarHBondContact OE1-NE 2.71Å; E326-R330 IonicContact OE1-NH2 2.7Å; E326-R330 PolarHBondContact OE1-NH2 3.1Å; K327-R330 PolarHBondContact O-N 2.66Å; R330-T332 VanDerWaalsContact C-N 3.29Å; R330-T332 PolarHBondContact O-N 3.37Å; R330-V333 PolarHBondContact O-N 3.48Å; R330-E334 VanDerWaalsContact O-CB 3.28Å; R330-E334 WeakPolarHBondContact O-CB 3.15Å; R330-E334 PolarHBondContact O-N 3.34Å
331E89.8Confident90.4Very high65 Ų65111.8 Ų111.830%0.30452%0.517SS..Hα-helixtrans-60.9-32.7176.2-72.6172.9-158.800113.2K327 K328 R335K327-E331 IonicContact NZ-OE1 2.66Å; K327-E331 PolarHBondContact NZ-OE1 2.95Å; K327-E331 WeakPolarHBondContact O-CG 3.3Å; K327-E331 PolarHBondContact O-N 3.26Å; K328-E331 PolarHBondContact O-N 2.89Å; E331-R335 WeakPolarHBondContact O-CD 3.34Å; E331-R335 VanDerWaalsContact O-CG 3.25Å; E331-R335 WeakPolarHBondContact O-CG 3.24Å; E331-R335 PolarHBondContact O-N 3.48Å
332T91.7Very high90.6Very high66 Ų66114.1 Ų114.141%0.40552%0.522SS..Hα-helixtrans-74-47.417352.30000112.1K328 R329 R330 E334 R335 E336K328-T332 PolarHBondContact O-N 2.74Å; K328-T332 PolarHBondContact O-OG1 2.9Å; R329-T332 PolarHBondContact O-OG1 3.28Å; R330-T332 VanDerWaalsContact C-N 3.29Å; R330-T332 PolarHBondContact O-N 3.37Å; T332-E334 VanDerWaalsContact C-N 3.27Å; T332-E334 PolarHBondContact O-N 2.98Å; T332-R335 PolarHBondContact O-N 3.08Å; T332-R335 VanDerWaalsContact O-N 3.17Å; T332-E336 WeakPolarHBondContact O-CG 3.14Å; T332-E336 PolarHBondContact O-N 3.17Å
333V91.8Very high90.8Very high81 Ų81112.2 Ų112.249%0.49151%0.513SS..Hα-helixtrans-62.9-34.2179170.40000111.9R329 R330 K337R329-V333 WeakPolarHBondContact O-CG2 3.37Å; R329-V333 PolarHBondContact O-N 2.89Å; R329-V333 VanDerWaalsContact O-N 3.09Å; R330-V333 PolarHBondContact O-N 3.48Å; V333-K337 VanDerWaalsContact O-CB 3.23Å; V333-K337 WeakPolarHBondContact O-CB 3.48Å; V333-K337 PolarHBondContact O-N 3.04Å
334E89.4Confident91Very high126 Ų126112 Ų11259%0.58951%0.507SS*.Hα-helixtrans-66.7-42.2175-173.2160.1-128.700111.9R330 T332 K337 E338R330-E334 VanDerWaalsContact O-CB 3.28Å; R330-E334 WeakPolarHBondContact O-CB 3.15Å; R330-E334 PolarHBondContact O-N 3.34Å; T332-E334 VanDerWaalsContact C-N 3.27Å; T332-E334 PolarHBondContact O-N 2.98Å; E334-K337 PolarHBondContact O-N 3.12Å; E334-E338 PolarHBondContact O-N 3.26Å
335R91.9Very high91.3Very high163 Ų163113.3 Ų113.362%0.61551%0.513SS*.Hα-helixtrans-67.2-41.9174.2-70.4171.8-167.517210112.9E331 T332 K337 E338 Q339E331-R335 WeakPolarHBondContact O-CD 3.34Å; E331-R335 VanDerWaalsContact O-CG 3.25Å; E331-R335 WeakPolarHBondContact O-CG 3.24Å; E331-R335 PolarHBondContact O-N 3.48Å; T332-R335 PolarHBondContact O-N 3.08Å; T332-R335 VanDerWaalsContact O-N 3.17Å; R335-K337 VanDerWaalsContact C-N 3.29Å; R335-K337 PolarHBondContact O-N 2.83Å; R335-E338 PolarHBondContact O-N 2.84Å; R335-Q339 WeakPolarHBondContact O-CB 3.38Å; R335-Q339 PolarHBondContact O-N 3.27Å
336E92.7Very high91.5Very high109 Ų109113.8 Ų113.851%0.50951%0.509SS..Hα-helixtrans-60.6-41174.2-72.8166-17500110.8T332 Q339 M340T332-E336 WeakPolarHBondContact O-CG 3.14Å; T332-E336 PolarHBondContact O-N 3.17Å; E336-Q339 PolarHBondContact O-N 3.27Å; E336-M340 WeakPolarHBondContact O-CB 3.36Å; E336-M340 WeakPolarHBondContact O-CG 3.36Å; E336-M340 PolarHBondContact O-N 3.39Å
337K92.2Very high91.7Very high136 Ų136115 Ų11559%0.59152%0.517SS*.Hα-helixtrans-66.2-42.3174.3-176.9-173.4174-167.30112.5V333 E334 R335 Q339 M341V333-K337 VanDerWaalsContact O-CB 3.23Å; V333-K337 WeakPolarHBondContact O-CB 3.48Å; V333-K337 PolarHBondContact O-N 3.04Å; E334-K337 PolarHBondContact O-N 3.12Å; R335-K337 VanDerWaalsContact C-N 3.29Å; R335-K337 PolarHBondContact O-N 2.83Å; K337-Q339 VanDerWaalsContact C-N 3.33Å; K337-M341 WeakPolarHBondContact O-CB 3.49Å; K337-M341 VanDerWaalsContact O-CG 3.26Å; K337-M341 WeakPolarHBondContact O-CG 3.4Å; K337-M341 PolarHBondContact O-N 2.77Å
338E92Very high91.9Very high99 Ų99113.4 Ų113.446%0.46351%0.513SS..Hα-helixtrans-60-43.3172.6-83.1-164.8-158.500111.9E334 R335 M341 R342E334-E338 PolarHBondContact O-N 3.26Å; R335-E338 PolarHBondContact O-N 2.84Å; E338-M341 PolarHBondContact O-N 3.17Å; E338-R342 WeakPolarHBondContact O-CG 3.5Å; E338-R342 PolarHBondContact O-N 2.79Å; E338-R342 VanDerWaalsContact O-N 3.09Å; E338-R342 IonicContact OE2-CZ 3.55Å; E338-R342 IonicContact OE2-NH2 3.94Å; E338-R342 PolarHBondContact OE2-NH2 3.48Å
339Q92.9Very high92.2Very high115 Ų115112.9 Ų112.954%0.53752%0.515SS..Hα-helixtrans-63.6-50.1177.9-179.1175.4-23.600111.1R335 E336 K337 M341 R342 E343R335-Q339 WeakPolarHBondContact O-CB 3.38Å; R335-Q339 PolarHBondContact O-N 3.27Å; E336-Q339 PolarHBondContact O-N 3.27Å; K337-Q339 VanDerWaalsContact C-N 3.33Å; Q339-M341 PolarHBondContact O-N 2.98Å; Q339-R342 PolarHBondContact O-N 3.07Å; Q339-R342 VanDerWaalsContact O-N 3.1Å; Q339-E343 HydrophobicContact CG-CG 4.4Å; Q339-E343 VanDerWaalsContact CG-OE1 3.29Å; Q339-E343 WeakPolarHBondContact CG-OE1 3.38Å; Q339-E343 PolarHBondContact NE2-OE1 3.2Å; Q339-E343 WeakPolarHBondContact O-CG 3.49Å; Q339-E343 PolarHBondContact O-N 3.19Å
340M92.8Very high92.4Very high119 Ų119111.3 Ų111.359%0.58651%0.509SS*.Hα-helixtrans-60-32.7176.2-74.6-170.9-69.400113E336 K344E336-M340 WeakPolarHBondContact O-CB 3.36Å; E336-M340 WeakPolarHBondContact O-CG 3.36Å; E336-M340 PolarHBondContact O-N 3.39Å; M340-K344 WeakPolarHBondContact O-CB 3.28Å; M340-K344 PolarHBondContact O-N 3.45Å
341M91.9Very high92.5Very high89 Ų89108.7 Ų108.744%0.43851%0.507SS..Hα-helixtrans-65-46.1173.5-79.1-70.7-60.900111.6K337 E338 Q339 K344 E345K337-M341 WeakPolarHBondContact O-CB 3.49Å; K337-M341 VanDerWaalsContact O-CG 3.26Å; K337-M341 WeakPolarHBondContact O-CG 3.4Å; K337-M341 PolarHBondContact O-N 2.77Å; E338-M341 PolarHBondContact O-N 3.17Å; Q339-M341 PolarHBondContact O-N 2.98Å; M341-K344 WeakPolarHBondContact O-CB 3.1Å; M341-K344 PolarHBondContact O-N 2.95Å; M341-E345 WeakPolarHBondContact O-CG 3.38Å; M341-E345 PolarHBondContact O-N 3.04Å
342R93.3Very high92.5Very high150 Ų150111.1 Ų111.157%0.56652%0.518SS*.Hα-helixtrans-65.2-43.8177.3-63.9172.6-157.2-161.77.9111.9E338 Q339 K344 E345 E346E338-R342 WeakPolarHBondContact O-CG 3.5Å; E338-R342 PolarHBondContact O-N 2.79Å; E338-R342 VanDerWaalsContact O-N 3.09Å; E338-R342 IonicContact OE2-CZ 3.55Å; E338-R342 IonicContact OE2-NH2 3.94Å; E338-R342 PolarHBondContact OE2-NH2 3.48Å; Q339-R342 PolarHBondContact O-N 3.07Å; Q339-R342 VanDerWaalsContact O-N 3.1Å; R342-K344 VanDerWaalsContact C-N 3.3Å; R342-K344 PolarHBondContact O-N 3.07Å; R342-E345 PolarHBondContact O-N 3.02Å; R342-E345 VanDerWaalsContact O-N 3.17Å; R342-E346 PolarHBondContact O-N 2.98Å
343E93.3Very high92.6Very high93 Ų93111.1 Ų111.144%0.43552%0.515SS..Hα-helixtrans-61.7-38.5175.7-71.3174.6-172.500111.8Q339 L347Q339-E343 HydrophobicContact CG-CG 4.4Å; Q339-E343 VanDerWaalsContact CG-OE1 3.29Å; Q339-E343 WeakPolarHBondContact CG-OE1 3.38Å; Q339-E343 PolarHBondContact NE2-OE1 3.2Å; Q339-E343 WeakPolarHBondContact O-CG 3.49Å; Q339-E343 PolarHBondContact O-N 3.19Å; E343-L347 WeakPolarHBondContact O-CB 3.46Å; E343-L347 WeakPolarHBondContact O-CG 3.4Å; E343-L347 PolarHBondContact O-N 3.37Å
344K92.4Very high92.5Very high122 Ų122114.3 Ų114.353%0.5352%0.52SS..Hα-helixtrans-65.7-40.4172.8179.6-173.9174.1-171.30112.4M340 M341 R342 L347 M348M340-K344 WeakPolarHBondContact O-CB 3.28Å; M340-K344 PolarHBondContact O-N 3.45Å; M341-K344 WeakPolarHBondContact O-CB 3.1Å; M341-K344 PolarHBondContact O-N 2.95Å; R342-K344 VanDerWaalsContact C-N 3.3Å; R342-K344 PolarHBondContact O-N 3.07Å; K344-L347 PolarHBondContact O-N 3.31Å; K344-M348 WeakPolarHBondContact O-CG 3.27Å; K344-M348 PolarHBondContact O-N 3.1Å
345E92.6Very high92.5Very high97 Ų97113.4 Ų113.445%0.45352%0.516SS..Hα-helixtrans-64.9-44.7176.4-75.1168.1-179.600111.2M341 R342 L347 M348 L349M341-E345 WeakPolarHBondContact O-CG 3.38Å; M341-E345 PolarHBondContact O-N 3.04Å; R342-E345 PolarHBondContact O-N 3.02Å; R342-E345 VanDerWaalsContact O-N 3.17Å; E345-L347 VanDerWaalsContact C-N 3.35Å; E345-L347 PolarHBondContact O-N 3.33Å; E345-M348 HydrophobicContact CG-CE 4.28Å; E345-M348 PolarHBondContact O-N 3.12Å; E345-L349 WeakPolarHBondContact O-CG 3.33Å; E345-L349 PolarHBondContact O-N 2.86Å
346E94.3Very high92.5Very high104 Ų104112.5 Ų112.549%0.48652%0.518SS..Hα-helixtrans-59.3-42.4171.3-76.8-165.7-146.800112.7R342 L349 R350R342-E346 PolarHBondContact O-N 2.98Å; E346-L349 PolarHBondContact O-N 2.65Å; E346-R350 WeakPolarHBondContact O-CG 3.25Å; E346-R350 PolarHBondContact O-N 3.4Å; E346-R350 IonicContact OE2-CZ 2.69Å; E346-R350 IonicContact OE2-NH2 2.69Å; E346-R350 PolarHBondContact OE2-NH2 2.75Å
347L94.6Very high92.4Very high99 Ų99112.7 Ų112.752%0.51852%0.517SS..Hα-helixtrans-64.5-39.8177-83.5163.4000112.3E343 K344 E345 R350 L351E343-L347 WeakPolarHBondContact O-CB 3.46Å; E343-L347 WeakPolarHBondContact O-CG 3.4Å; E343-L347 PolarHBondContact O-N 3.37Å; K344-L347 PolarHBondContact O-N 3.31Å; E345-L347 VanDerWaalsContact C-N 3.35Å; E345-L347 PolarHBondContact O-N 3.33Å; L347-R350 PolarHBondContact O-N 3.06Å; L347-L351 WeakPolarHBondContact O-CB 3.46Å; L347-L351 WeakPolarHBondContact O-CG 3.47Å; L347-L351 PolarHBondContact O-N 3.14Å
348M92.9Very high92.2Very high91 Ų91109.9 Ų109.945%0.44851%0.512SS..Hα-helixtrans-63.9-42.6174.1-74.2-168.7-56.600111.9K344 E345 R350 L351 Q352K344-M348 WeakPolarHBondContact O-CG 3.27Å; K344-M348 PolarHBondContact O-N 3.1Å; E345-M348 HydrophobicContact CG-CE 4.28Å; E345-M348 PolarHBondContact O-N 3.12Å; M348-R350 VanDerWaalsContact C-N 3.34Å; M348-R350 PolarHBondContact O-N 2.91Å; M348-L351 PolarHBondContact O-N 2.89Å; M348-Q352 WeakPolarHBondContact O-CG 3.36Å; M348-Q352 PolarHBondContact O-N 2.78Å
349L94.6Very high92.1Very high112 Ų112109.3 Ų109.359%0.58651%0.508SS*.Hα-helixtrans-62.7-40.3176.8-70.2169.6000111.8E345 E346 Q352 D353E345-L349 WeakPolarHBondContact O-CG 3.33Å; E345-L349 PolarHBondContact O-N 2.86Å; E346-L349 PolarHBondContact O-N 2.65Å; L349-Q352 PolarHBondContact O-N 2.82Å; L349-D353 PolarHBondContact O-N 3.42Å; L349-D353 VanDerWaalsContact O-N 3.08Å
350R94.1Very high92.1Very high138 Ų138109.6 Ų109.652%0.52151%0.507SS..Hα-helixtrans-65.8-40.8173.8-67.6174.9-158.7-1799112E346 L347 M348 Q352 D353 Y354E346-R350 WeakPolarHBondContact O-CG 3.25Å; E346-R350 PolarHBondContact O-N 3.4Å; E346-R350 IonicContact OE2-CZ 2.69Å; E346-R350 IonicContact OE2-NH2 2.69Å; E346-R350 PolarHBondContact OE2-NH2 2.75Å; L347-R350 PolarHBondContact O-N 3.06Å; M348-R350 VanDerWaalsContact C-N 3.34Å; M348-R350 PolarHBondContact O-N 2.91Å; R350-Q352 VanDerWaalsContact C-N 3.34Å; R350-Q352 PolarHBondContact O-N 3.47Å; R350-D353 PolarHBondContact O-N 3.06Å; R350-Y354 WeakPolarHBondContact O-CD2 3.45Å; R350-Y354 PolarHBondContact O-N 3.49Å
351L90.5Very high91.9Very high109 Ų109106.5 Ų106.557%0.57150%0.501SS*.Hα-helixtrans-64.3-37.4176.1-74.7169000112.2L347 M348 Y354 E355L347-L351 WeakPolarHBondContact O-CB 3.46Å; L347-L351 WeakPolarHBondContact O-CG 3.47Å; L347-L351 PolarHBondContact O-N 3.14Å; M348-L351 PolarHBondContact O-N 2.89Å; L351-Y354 PolarHBondContact O-N 2.64Å; L351-E355 PolarHBondContact O-N 3.23Å
352Q91.1Very high91.6Very high116 Ų116108 Ų10854%0.54251%0.507SS..Hα-helixtrans-64-45.4173.6-73.6174.2-14.700111.9M348 L349 R350 Y354 E355 E356M348-Q352 WeakPolarHBondContact O-CG 3.36Å; M348-Q352 PolarHBondContact O-N 2.78Å; L349-Q352 PolarHBondContact O-N 2.82Å; R350-Q352 VanDerWaalsContact C-N 3.34Å; R350-Q352 PolarHBondContact O-N 3.47Å; Q352-Y354 PolarHBondContact O-N 3.02Å; Q352-E355 PolarHBondContact O-N 3.44Å; Q352-E356 PolarHBondContact O-N 2.81Å
353D92.6Very high91.5Very high65 Ų65109 Ų10935%0.34851%0.511SS..Hα-helixtrans-59.6-41.3173.5168.174.2000112.5L349 R350 E356 K357L349-D353 PolarHBondContact O-N 3.42Å; L349-D353 VanDerWaalsContact O-N 3.08Å; R350-D353 PolarHBondContact O-N 3.06Å; D353-E356 PolarHBondContact O-N 3.41Å; D353-K357 WeakPolarHBondContact O-CB 3.41Å; D353-K357 WeakPolarHBondContact O-CD 3.45Å; D353-K357 VanDerWaalsContact O-CG 3.27Å; D353-K357 WeakPolarHBondContact O-CG 3.17Å; D353-K357 PolarHBondContact O-N 3.45Å; D353-K357 WeakPolarHBondContact OD1-CE 3.04Å; D353-K357 IonicContact OD1-NZ 2.75Å; D353-K357 PolarHBondContact OD1-NZ 2.84Å; D353-K357 IonicContact OD2-NZ 3.47Å; D353-K357 PolarHBondContact OD2-NZ 2.82Å
354Y90.2Very high91.3Very high148 Ų148108.8 Ų108.858%0.5851%0.509SS*.Hα-helixtrans-65.9-40.3172.7-77-60.3000112.9R350 L351 Q352 T358R350-Y354 WeakPolarHBondContact O-CD2 3.45Å; R350-Y354 PolarHBondContact O-N 3.49Å; L351-Y354 PolarHBondContact O-N 2.64Å; Q352-Y354 PolarHBondContact O-N 3.02Å; Y354-T358 WeakPolarHBondContact O-CB 3.48Å; Y354-T358 PolarHBondContact O-N 3.4Å; Y354-T358 PolarHBondContact O-OG1 2.83Å
355E89.1Confident91.1Very high108 Ų108107.6 Ų107.651%0.50551%0.508SS..Hα-helixtrans-63.4-43.6174.6-87.9-165.6-148.400112L351 Q352 T358 K359L351-E355 PolarHBondContact O-N 3.23Å; Q352-E355 PolarHBondContact O-N 3.44Å; E355-T358 PolarHBondContact O-N 3.22Å; E355-K359 WeakPolarHBondContact O-CB 3.36Å; E355-K359 WeakPolarHBondContact O-CD 3.48Å; E355-K359 VanDerWaalsContact O-CG 3.22Å; E355-K359 WeakPolarHBondContact O-CG 3.05Å; E355-K359 PolarHBondContact O-N 3.34Å; E355-K359 IonicContact OE2-NZ 2.69Å; E355-K359 PolarHBondContact OE2-NZ 3.06Å
356E92Very high91Very high144 Ų144105.9 Ų105.967%0.67351%0.507SS*.Hα-helixtrans-65.3-43.1177.4-72.7-163.416100111.8Q352 D353 T358 K359 K360Q352-E356 PolarHBondContact O-N 2.81Å; D353-E356 PolarHBondContact O-N 3.41Å; E356-T358 VanDerWaalsContact C-N 3.34Å; E356-T358 PolarHBondContact O-N 3.15Å; E356-K359 PolarHBondContact O-N 2.96Å; E356-K360 VanDerWaalsContact O-CB 3.28Å; E356-K360 WeakPolarHBondContact O-CB 3.47Å; E356-K360 PolarHBondContact O-N 3.47Å
357K91.1Very high90.8Very high112 Ų112105.2 Ų105.249%0.48750%0.504SS..Hα-helixtrans-61.3-41.3173.9-76.2166.2177.9162.40112.1D353 K360 A361D353-K357 WeakPolarHBondContact O-CB 3.41Å; D353-K357 WeakPolarHBondContact O-CD 3.45Å; D353-K357 VanDerWaalsContact O-CG 3.27Å; D353-K357 WeakPolarHBondContact O-CG 3.17Å; D353-K357 PolarHBondContact O-N 3.45Å; D353-K357 WeakPolarHBondContact OD1-CE 3.04Å; D353-K357 IonicContact OD1-NZ 2.75Å; D353-K357 PolarHBondContact OD1-NZ 2.84Å; D353-K357 IonicContact OD2-NZ 3.47Å; D353-K357 PolarHBondContact OD2-NZ 2.82Å; K357-K360 PolarHBondContact O-N 3.01Å; K357-A361 WeakPolarHBondContact O-CB 3.45Å; K357-A361 PolarHBondContact O-N 3.24Å
358T87.6Confident90.4Very high77 Ų77106.5 Ų106.547%0.47251%0.507SS..Hα-helixtrans-65.2-51.1177-55.20000110.6Y354 E355 E356 K360 A361 E362Y354-T358 WeakPolarHBondContact O-CB 3.48Å; Y354-T358 PolarHBondContact O-N 3.4Å; Y354-T358 PolarHBondContact O-OG1 2.83Å; E355-T358 PolarHBondContact O-N 3.22Å; E356-T358 VanDerWaalsContact C-N 3.34Å; E356-T358 PolarHBondContact O-N 3.15Å; T358-K360 PolarHBondContact O-N 2.77Å; T358-A361 PolarHBondContact O-N 3.24Å; T358-A361 VanDerWaalsContact O-N 3.08Å; T358-E362 HydrophobicContact CG2-CG 4.47Å; T358-E362 WeakPolarHBondContact O-CG 3.49Å; T358-E362 PolarHBondContact O-N 2.89Å
359K91.2Very high90.2Very high87 Ų87106.5 Ų106.538%0.37851%0.508SS..Hα-helixtrans-60.5-30.6176.8-69.5162.5-168.1165.90112.8E355 E356 R363E355-K359 WeakPolarHBondContact O-CB 3.36Å; E355-K359 WeakPolarHBondContact O-CD 3.48Å; E355-K359 VanDerWaalsContact O-CG 3.22Å; E355-K359 WeakPolarHBondContact O-CG 3.05Å; E355-K359 PolarHBondContact O-N 3.34Å; E355-K359 IonicContact OE2-NZ 2.69Å; E355-K359 PolarHBondContact OE2-NZ 3.06Å; E356-K359 PolarHBondContact O-N 2.96Å; K359-R363 WeakPolarHBondContact O-CD 3.46Å; K359-R363 VanDerWaalsContact O-CG 3.23Å; K359-R363 WeakPolarHBondContact O-CG 3.39Å; K359-R363 PolarHBondContact O-N 2.98Å
360K91.4Very high89.9Confident121 Ų121106.9 Ų106.953%0.52651%0.507SS..Hα-helixtrans-71.3-45.8173.3-174.1171.9-178.3-69.90111.5E356 K357 T358 R363 E364E356-K360 VanDerWaalsContact O-CB 3.28Å; E356-K360 WeakPolarHBondContact O-CB 3.47Å; E356-K360 PolarHBondContact O-N 3.47Å; K357-K360 PolarHBondContact O-N 3.01Å; T358-K360 PolarHBondContact O-N 2.77Å; K360-R363 PolarHBondContact O-N 2.89Å; K360-E364 WeakPolarHBondContact CE-OE1 3.49Å; K360-E364 IonicContact NZ-OE1 3.58Å; K360-E364 PolarHBondContact NZ-OE1 3.38Å; K360-E364 WeakPolarHBondContact O-CG 3.17Å; K360-E364 PolarHBondContact O-N 2.96Å
361A88.5Confident89.7Confident55 Ų55107 Ų10746%0.45551%0.508SS..Hα-helixtrans-63.7-38.4175.400000112.6K357 T358 E364 L365K357-A361 WeakPolarHBondContact O-CB 3.45Å; K357-A361 PolarHBondContact O-N 3.24Å; T358-A361 PolarHBondContact O-N 3.24Å; T358-A361 VanDerWaalsContact O-N 3.08Å; A361-E364 PolarHBondContact O-N 3.09Å; A361-L365 VanDerWaalsContact O-CB 3.25Å; A361-L365 WeakPolarHBondContact O-CB 3.03Å; A361-L365 PolarHBondContact O-N 3.22Å
362E86.2Confident89.4Confident119 Ų119104.5 Ų104.556%0.55650%0.502SS*.Hα-helixtrans-61.7-42173.5-72.9174.2154.300112.2T358 S366T358-E362 HydrophobicContact CG2-CG 4.47Å; T358-E362 WeakPolarHBondContact O-CG 3.49Å; T358-E362 PolarHBondContact O-N 2.89Å; E362-S366 VanDerWaalsContact O-CB 3.29Å; E362-S366 WeakPolarHBondContact O-CB 3.29Å; E362-S366 PolarHBondContact O-N 2.8Å
363R90.8Very high89.4Confident173 Ų173103.9 Ų103.965%0.65350%0.503SS*.Hα-helixtrans-65.2-47.4174.2-72168-170.2176.84.4111.7K359 K360 L365 S366 E367K359-R363 WeakPolarHBondContact O-CD 3.46Å; K359-R363 VanDerWaalsContact O-CG 3.23Å; K359-R363 WeakPolarHBondContact O-CG 3.39Å; K359-R363 PolarHBondContact O-N 2.98Å; K360-R363 PolarHBondContact O-N 2.89Å; R363-L365 VanDerWaalsContact C-N 3.31Å; R363-L365 PolarHBondContact O-N 3.33Å; R363-S366 PolarHBondContact O-N 3.48Å; R363-S366 VanDerWaalsContact O-N 3.17Å; R363-E367 PolarHBondContact O-N 3.36Å
364E89.9Confident89.1Confident87 Ų87106.5 Ų106.541%0.40751%0.513SS..Hα-helixtrans-61.8-39.1178.3-74.3171.9-171.800112K360 A361 Q368K360-E364 WeakPolarHBondContact CE-OE1 3.49Å; K360-E364 IonicContact NZ-OE1 3.58Å; K360-E364 PolarHBondContact NZ-OE1 3.38Å; K360-E364 WeakPolarHBondContact O-CG 3.17Å; K360-E364 PolarHBondContact O-N 2.96Å; A361-E364 PolarHBondContact O-N 3.09Å; E364-Q368 WeakPolarHBondContact O-CB 3.32Å; E364-Q368 VanDerWaalsContact O-CG 3.27Å; E364-Q368 WeakPolarHBondContact O-CG 3.26Å; E364-Q368 PolarHBondContact O-N 3.34Å
365L88.1Confident88.9Confident97 Ų97104.8 Ų104.851%0.50851%0.513SS..Hα-helixtrans-67-41.8173.1-179.561.4000111.9A361 R363 Q368 I369A361-L365 VanDerWaalsContact O-CB 3.25Å; A361-L365 WeakPolarHBondContact O-CB 3.03Å; A361-L365 PolarHBondContact O-N 3.22Å; R363-L365 VanDerWaalsContact C-N 3.31Å; R363-L365 PolarHBondContact O-N 3.33Å; L365-Q368 PolarHBondContact O-N 2.72Å; L365-I369 HydrophobicContact CD1-CD1 4.23Å; L365-I369 HydrophobicContact CD1-CG1 4.45Å; L365-I369 HydrophobicContact CG-CD1 4.01Å; L365-I369 VanDerWaalsContact O-CG1 3.29Å; L365-I369 WeakPolarHBondContact O-CG1 3.47Å; L365-I369 PolarHBondContact O-N 3.27Å
366S89.4Confident88.6Confident62 Ų62105.5 Ų105.543%0.43452%0.516SS..Hα-helixtrans-63-42.6176.2-170.20000111.9E362 R363 I369 Q370E362-S366 VanDerWaalsContact O-CB 3.29Å; E362-S366 WeakPolarHBondContact O-CB 3.29Å; E362-S366 PolarHBondContact O-N 2.8Å; R363-S366 PolarHBondContact O-N 3.48Å; R363-S366 VanDerWaalsContact O-N 3.17Å; S366-I369 PolarHBondContact O-N 3.17Å; S366-Q370 WeakPolarHBondContact O-CG 3.24Å; S366-Q370 PolarHBondContact O-N 3.19Å
367E90.8Very high88.4Confident90 Ų90103.5 Ų103.542%0.42151%0.507SS..Hα-helixtrans-62.6-41.8171.8-75.6-172.7-137.500112.2R363 Q370 R371R363-E367 PolarHBondContact O-N 3.36Å; E367-Q370 PolarHBondContact O-N 3.32Å; E367-R371 WeakPolarHBondContact O-CB 3.47Å; E367-R371 VanDerWaalsContact O-CG 3.23Å; E367-R371 WeakPolarHBondContact O-CG 3.48Å; E367-R371 PolarHBondContact O-N 3.37Å; E367-R371 IonicContact OE2-CZ 3.23Å; E367-R371 IonicContact OE2-NH2 3.69Å; E367-R371 PolarHBondContact OE2-NH2 2.82Å
368Q86.8Confident88.1Confident125 Ų125103.9 Ų103.958%0.58451%0.51SS*.Hα-helixtrans-62.7-41.5175.7-76.5175.32700111.9E364 L365 R371 A372E364-Q368 WeakPolarHBondContact O-CB 3.32Å; E364-Q368 VanDerWaalsContact O-CG 3.27Å; E364-Q368 WeakPolarHBondContact O-CG 3.26Å; E364-Q368 PolarHBondContact O-N 3.34Å; L365-Q368 PolarHBondContact O-N 2.72Å; Q368-R371 PolarHBondContact O-N 3.26Å; Q368-A372 VanDerWaalsContact O-CB 3.3Å; Q368-A372 WeakPolarHBondContact O-CB 3.36Å; Q368-A372 PolarHBondContact O-N 3.19Å
369I88.4Confident88Confident91 Ų91107.8 Ų107.847%0.46752%0.516SS..Hα-helixtrans-63.5-44.4175.5-69.6164.4000110.7L365 S366 A372 L373L365-I369 HydrophobicContact CD1-CD1 4.23Å; L365-I369 HydrophobicContact CD1-CG1 4.45Å; L365-I369 HydrophobicContact CG-CD1 4.01Å; L365-I369 VanDerWaalsContact O-CG1 3.29Å; L365-I369 WeakPolarHBondContact O-CG1 3.47Å; L365-I369 PolarHBondContact O-N 3.27Å; S366-I369 PolarHBondContact O-N 3.17Å; I369-A372 PolarHBondContact O-N 3.27Å; I369-L373 HydrophobicContact CG2-CD1 4.06Å; I369-L373 WeakPolarHBondContact O-CG 3.35Å; I369-L373 PolarHBondContact O-N 3.4Å
370Q88.9Confident87.7Confident121 Ų121109.4 Ų109.457%0.56552%0.523SS*.Hα-helixtrans-62.5-43.7176.3-75.2-173.5-13.800112.5S366 E367 L373 Q374S366-Q370 WeakPolarHBondContact O-CG 3.24Å; S366-Q370 PolarHBondContact O-N 3.19Å; E367-Q370 PolarHBondContact O-N 3.32Å; Q370-L373 PolarHBondContact O-N 3.43Å; Q370-Q374 WeakPolarHBondContact O-CG 3.25Å; Q370-Q374 PolarHBondContact O-N 2.75Å
371R89.1Confident87.4Confident140 Ų140110.8 Ų110.853%0.52853%0.525SS..Hα-helixtrans-65.6-37.9176.2-67172.9-156.5-166.58.6112E367 Q368 Q374 L375E367-R371 WeakPolarHBondContact O-CB 3.47Å; E367-R371 VanDerWaalsContact O-CG 3.23Å; E367-R371 WeakPolarHBondContact O-CG 3.48Å; E367-R371 PolarHBondContact O-N 3.37Å; E367-R371 IonicContact OE2-CZ 3.23Å; E367-R371 IonicContact OE2-NH2 3.69Å; E367-R371 PolarHBondContact OE2-NH2 2.82Å; Q368-R371 PolarHBondContact O-N 3.26Å; R371-Q374 PolarHBondContact O-N 2.81Å; R371-L375 WeakPolarHBondContact O-CB 3.44Å; R371-L375 VanDerWaalsContact O-CG 3.29Å; R371-L375 WeakPolarHBondContact O-CG 3.31Å; R371-L375 PolarHBondContact O-N 3.33Å
372A85.3Confident87.1Confident56 Ų56111 Ų11146%0.46353%0.528SS..Hα-helixtrans-64-43.9175.900000111.8Q368 I369 L375 E376Q368-A372 VanDerWaalsContact O-CB 3.3Å; Q368-A372 WeakPolarHBondContact O-CB 3.36Å; Q368-A372 PolarHBondContact O-N 3.19Å; I369-A372 PolarHBondContact O-N 3.27Å; A372-L375 PolarHBondContact O-N 3.25Å; A372-E376 WeakPolarHBondContact O-CB 3.39Å; A372-E376 PolarHBondContact O-N 3.05Å
373L89.6Confident86.8Confident104 Ų104109.2 Ų109.255%0.54552%0.519SS..Hα-helixtrans-62.8-41.5174.8-72.2166.8000112.2I369 Q370 E376 E377I369-L373 HydrophobicContact CG2-CD1 4.06Å; I369-L373 WeakPolarHBondContact O-CG 3.35Å; I369-L373 PolarHBondContact O-N 3.4Å; Q370-L373 PolarHBondContact O-N 3.43Å; L373-E376 PolarHBondContact O-N 3.43Å; L373-E377 PolarHBondContact O-N 2.97Å
374Q87.9Confident86.5Confident120 Ų120105.7 Ų105.756%0.56151%0.51SS*.Hα-helixtrans-61.9-46.5174.6-75173.2-21.900111.8Q370 R371 E376 E377 E378Q370-Q374 WeakPolarHBondContact O-CG 3.25Å; Q370-Q374 PolarHBondContact O-N 2.75Å; R371-Q374 PolarHBondContact O-N 2.81Å; Q374-E376 VanDerWaalsContact C-N 3.33Å; Q374-E376 PolarHBondContact O-N 2.94Å; Q374-E377 PolarHBondContact O-N 3.04Å; Q374-E378 WeakPolarHBondContact O-CG 3.35Å; Q374-E378 PolarHBondContact O-N 2.6Å
375L85.4Confident86.1Confident111 Ų111106 Ų10658%0.58151%0.512SS*.Hα-helixtrans-65.6-33.6177.2-71.9168.5000112.5R371 A372 R379R371-L375 WeakPolarHBondContact O-CB 3.44Å; R371-L375 VanDerWaalsContact O-CG 3.29Å; R371-L375 WeakPolarHBondContact O-CG 3.31Å; R371-L375 PolarHBondContact O-N 3.33Å; A372-L375 PolarHBondContact O-N 3.25Å; L375-R379 WeakPolarHBondContact O-CB 3.48Å; L375-R379 PolarHBondContact O-N 3.3Å
376E83Confident85.7Confident123 Ų123104 Ų10458%0.57551%0.509SS*.Hα-helixtrans-68.5-40.6173.3-175.4167.5-152.400111.6A372 L373 Q374 R379 K380A372-E376 WeakPolarHBondContact O-CB 3.39Å; A372-E376 PolarHBondContact O-N 3.05Å; L373-E376 PolarHBondContact O-N 3.43Å; Q374-E376 VanDerWaalsContact C-N 3.33Å; Q374-E376 PolarHBondContact O-N 2.94Å; E376-R379 PolarHBondContact O-N 2.77Å; E376-K380 WeakPolarHBondContact O-CB 3.27Å; E376-K380 PolarHBondContact O-N 3.16Å
377E86.7Confident85.4Confident102 Ų102106.2 Ų106.248%0.47751%0.512SS..Hα-helixtrans-67.1-42.6175.4-159.4-172.3163.200112L373 Q374 K380 R381L373-E377 PolarHBondContact O-N 2.97Å; Q374-E377 PolarHBondContact O-N 3.04Å; E377-K380 PolarHBondContact O-N 2.72Å; E377-R381 VanDerWaalsContact O-CG 3.3Å; E377-R381 WeakPolarHBondContact O-CG 3.48Å; E377-R381 PolarHBondContact O-N 2.91Å; E377-R381 IonicContact OE1-CZ 3.76Å; E377-R381 IonicContact OE1-NE 2.77Å; E377-R381 PolarHBondContact OE1-NE 2.81Å; E377-R381 IonicContact OE1-NH2 3.57Å; E377-R381 PolarHBondContact OE1-NH2 3.48Å; E377-R381 IonicContact OE2-NH2 2.66Å
378E85.1Confident85.2Confident120 Ų120108 Ų10856%0.56152%0.515SS*.Hα-helixtrans-61.6-45.4172.5-74.7-177.2167.200111.7Q374 K380 R381 A382Q374-E378 WeakPolarHBondContact O-CG 3.35Å; Q374-E378 PolarHBondContact O-N 2.6Å; E378-K380 VanDerWaalsContact C-N 3.3Å; E378-K380 PolarHBondContact O-N 3.16Å; E378-R381 PolarHBondContact O-N 2.93Å; E378-A382 WeakPolarHBondContact O-CB 3.48Å; E378-A382 PolarHBondContact O-N 2.78Å
379R84.9Confident85Confident160 Ų160106.8 Ų106.860%0.60451%0.512SS*.Hα-helixtrans-60-40.7175.4-165-153.6110.2-170.33.9111.4L375 E376 A382 Q383L375-R379 WeakPolarHBondContact O-CB 3.48Å; L375-R379 PolarHBondContact O-N 3.3Å; E376-R379 PolarHBondContact O-N 2.77Å; R379-A382 PolarHBondContact O-N 2.74Å; R379-Q383 VanDerWaalsContact O-CB 3.31Å; R379-Q383 WeakPolarHBondContact O-CB 3.29Å; R379-Q383 PolarHBondContact O-N 2.79Å
380K85.3Confident84.6Confident120 Ų120108 Ų10852%0.52252%0.516SS..Hα-helixtrans-65.2-46.1178.4-173.3171.8-177.5-68.20111.4E376 E377 E378 A382 Q383 E384E376-K380 WeakPolarHBondContact O-CB 3.27Å; E376-K380 PolarHBondContact O-N 3.16Å; E377-K380 PolarHBondContact O-N 2.72Å; E378-K380 VanDerWaalsContact C-N 3.3Å; E378-K380 PolarHBondContact O-N 3.16Å; K380-A382 PolarHBondContact O-N 2.77Å; K380-Q383 PolarHBondContact O-N 2.6Å; K380-E384 IonicContact NZ-OE1 2.78Å; K380-E384 PolarHBondContact NZ-OE1 3.04Å; K380-E384 WeakPolarHBondContact O-CG 3.3Å; K380-E384 PolarHBondContact O-N 2.76Å
381R85.6Confident84.4Confident150 Ų150105 Ų10557%0.56651%0.512SS*.Hα-helixtrans-61.4-42.8174.6-67.5169.3-175.2-165.54.7112E377 E378 Q383 E384 E385E377-R381 VanDerWaalsContact O-CG 3.3Å; E377-R381 WeakPolarHBondContact O-CG 3.48Å; E377-R381 PolarHBondContact O-N 2.91Å; E377-R381 IonicContact OE1-CZ 3.76Å; E377-R381 IonicContact OE1-NE 2.77Å; E377-R381 PolarHBondContact OE1-NE 2.81Å; E377-R381 IonicContact OE1-NH2 3.57Å; E377-R381 PolarHBondContact OE1-NH2 3.48Å; E377-R381 IonicContact OE2-NH2 2.66Å; E378-R381 PolarHBondContact O-N 2.93Å; R381-Q383 VanDerWaalsContact C-N 3.34Å; R381-E384 PolarHBondContact O-N 3.4Å; R381-E385 PolarHBondContact O-N 3.38Å
382A81.3Confident84Confident61 Ų61102.9 Ų102.950%0.50451%0.511SS..Hα-helixtrans-66.4-34.9176.700000112.6E378 R379 K380 A386E378-A382 WeakPolarHBondContact O-CB 3.48Å; E378-A382 PolarHBondContact O-N 2.78Å; R379-A382 PolarHBondContact O-N 2.74Å; K380-A382 PolarHBondContact O-N 2.77Å; A382-A386 WeakPolarHBondContact O-CB 3.14Å; A382-A386 PolarHBondContact O-N 3.29Å
383Q79.8Confident83.9Confident81 Ų81108.1 Ų108.138%0.37952%0.519SS..Hα-helixtrans-69.4-44.1174.1-172.2179.4-32.600111.3R379 K380 R381 E385 A386 E387R379-Q383 VanDerWaalsContact O-CB 3.31Å; R379-Q383 WeakPolarHBondContact O-CB 3.29Å; R379-Q383 PolarHBondContact O-N 2.79Å; K380-Q383 PolarHBondContact O-N 2.6Å; R381-Q383 VanDerWaalsContact C-N 3.34Å; Q383-E385 VanDerWaalsContact C-N 3.3Å; Q383-E385 PolarHBondContact O-N 2.9Å; Q383-A386 PolarHBondContact O-N 3.47Å; Q383-E387 WeakPolarHBondContact CG-OE1 3.46Å; Q383-E387 PolarHBondContact NE2-OE1 2.75Å; Q383-E387 WeakPolarHBondContact O-CB 3.43Å; Q383-E387 WeakPolarHBondContact O-CG 3.3Å; Q383-E387 PolarHBondContact O-N 3.18Å
384E84.6Confident83.5Confident98 Ų98108 Ų10846%0.45852%0.517SS..Hα-helixtrans-60.7-36.6174.6-73.2168.1-179.800112.3K380 R381 R388K380-E384 IonicContact NZ-OE1 2.78Å; K380-E384 PolarHBondContact NZ-OE1 3.04Å; K380-E384 WeakPolarHBondContact O-CG 3.3Å; K380-E384 PolarHBondContact O-N 2.76Å; R381-E384 PolarHBondContact O-N 3.4Å; E384-R388 PolarHBondContact O-N 3.37Å; E384-R388 VanDerWaalsContact O-N 3.13Å
385E82.9Confident83.3Confident95 Ų95104.9 Ų104.944%0.44451%0.511SS..Hα-helixtrans-72.2-38.7172.7179.1145-115.100113R381 Q383 R388 L389R381-E385 PolarHBondContact O-N 3.38Å; Q383-E385 VanDerWaalsContact C-N 3.3Å; Q383-E385 PolarHBondContact O-N 2.9Å; E385-R388 WeakPolarHBondContact O-CB 3.4Å; E385-R388 PolarHBondContact O-N 3.5Å; E385-R388 IonicContact OE1-CZ 2.81Å; E385-R388 VanDerWaalsContact OE1-CZ 3.29Å; E385-R388 IonicContact OE1-NH1 2.82Å; E385-R388 PolarHBondContact OE1-NH1 3.39Å; E385-R388 IonicContact OE1-NH2 3.24Å; E385-R388 PolarHBondContact OE1-NH2 2.83Å; E385-L389 HydrophobicContact CG-CD1 4.1Å; E385-L389 WeakPolarHBondContact O-CG 3.44Å; E385-L389 PolarHBondContact O-N 2.76Å
386A79.2Confident83Confident55 Ų55102.6 Ų102.646%0.45551%0.509SS..Hα-helixtrans-63.7-43.6174.900000112A382 Q383 R388 L389 E390A382-A386 WeakPolarHBondContact O-CB 3.14Å; A382-A386 PolarHBondContact O-N 3.29Å; Q383-A386 PolarHBondContact O-N 3.47Å; A386-R388 VanDerWaalsContact C-N 3.32Å; A386-R388 PolarHBondContact O-N 3.09Å; A386-L389 PolarHBondContact O-N 2.86Å; A386-E390 WeakPolarHBondContact O-CB 3.49Å; A386-E390 PolarHBondContact O-N 3.45Å
387E83.6Confident82.9Confident108 Ų108100.9 Ų100.951%0.50550%0.503SS..Hα-helixtrans-62.7-37175.2-72.4173.6-160.600111.5Q383 A391Q383-E387 WeakPolarHBondContact CG-OE1 3.46Å; Q383-E387 PolarHBondContact NE2-OE1 2.75Å; Q383-E387 WeakPolarHBondContact O-CB 3.43Å; Q383-E387 WeakPolarHBondContact O-CG 3.3Å; Q383-E387 PolarHBondContact O-N 3.18Å; E387-A391 WeakPolarHBondContact O-CB 3.44Å; E387-A391 PolarHBondContact O-N 2.89Å
388R86.4Confident82.7Confident128 Ų128103.1 Ų103.148%0.48351%0.507SS..Hα-helixtrans-62.3-48.9171.8-165.3-170.979.5-126.1-2.9111.8E384 E385 A386 E390 A391 D392E384-R388 PolarHBondContact O-N 3.37Å; E384-R388 VanDerWaalsContact O-N 3.13Å; E385-R388 WeakPolarHBondContact O-CB 3.4Å; E385-R388 PolarHBondContact O-N 3.5Å; E385-R388 IonicContact OE1-CZ 2.81Å; E385-R388 VanDerWaalsContact OE1-CZ 3.29Å; E385-R388 IonicContact OE1-NH1 2.82Å; E385-R388 PolarHBondContact OE1-NH1 3.39Å; E385-R388 IonicContact OE1-NH2 3.24Å; E385-R388 PolarHBondContact OE1-NH2 2.83Å; A386-R388 VanDerWaalsContact C-N 3.32Å; A386-R388 PolarHBondContact O-N 3.09Å; R388-E390 VanDerWaalsContact C-N 3.31Å; R388-E390 PolarHBondContact O-N 2.85Å; R388-A391 WeakPolarHBondContact O-CB 3.39Å; R388-A391 PolarHBondContact O-N 3.32Å; R388-D392 PolarHBondContact O-N 2.96Å
389L82.1Confident82.5Confident98 Ų98100 Ų10051%0.51350%0.501SS..Hα-helixtrans-65.6-32.9179.9-70.3168.8000112.6E385 A386 R393E385-L389 HydrophobicContact CG-CD1 4.1Å; E385-L389 WeakPolarHBondContact O-CG 3.44Å; E385-L389 PolarHBondContact O-N 2.76Å; A386-L389 PolarHBondContact O-N 2.86Å; L389-R393 WeakPolarHBondContact O-CB 3.38Å; L389-R393 PolarHBondContact O-N 2.88Å
390E80.9Confident82.2Confident117 Ų11797.3 Ų97.355%0.54749%0.494SS..Hα-helixtrans-72.2-37.2173.6-175.2156.5-128.300112.2A386 R388 R393 M394A386-E390 WeakPolarHBondContact O-CB 3.49Å; A386-E390 PolarHBondContact O-N 3.45Å; R388-E390 VanDerWaalsContact C-N 3.31Å; R388-E390 PolarHBondContact O-N 2.85Å; E390-R393 PolarHBondContact O-N 3.37Å; E390-M394 WeakPolarHBondContact O-CB 3.28Å; E390-M394 WeakPolarHBondContact O-CG 3.37Å; E390-M394 PolarHBondContact O-N 3.17Å
391A82.9Confident81.9Confident59 Ų5997.7 Ų97.749%0.48850%0.498SS..Hα-helixtrans-62.5-44.8171.700000112.1E387 R388 R393 M394 A395E387-A391 WeakPolarHBondContact O-CB 3.44Å; E387-A391 PolarHBondContact O-N 2.89Å; R388-A391 WeakPolarHBondContact O-CB 3.39Å; R388-A391 PolarHBondContact O-N 3.32Å; A391-R393 PolarHBondContact O-N 2.76Å; A391-M394 PolarHBondContact O-N 2.89Å; A391-A395 PolarHBondContact O-N 3.3Å
392D80.6Confident81.5Confident95 Ų9596.9 Ų96.951%0.50850%0.5SS..Hα-helixtrans-60.2-44.6174.5-71.7-29.2000111.2R388 M394 A395 A396R388-D392 PolarHBondContact O-N 2.96Å; D392-M394 PolarHBondContact O-N 3.44Å; D392-A395 PolarHBondContact O-N 3.48Å; D392-A396 PolarHBondContact O-N 2.81Å
393R85.1Confident81.2Confident166 Ų16699.4 Ų99.463%0.62651%0.505SS*.Hα-helixtrans-61.8-42.2175.3-178.9-176.6177-163.7-1.1112.3L389 E390 A391 A396 L397L389-R393 WeakPolarHBondContact O-CB 3.38Å; L389-R393 PolarHBondContact O-N 2.88Å; E390-R393 PolarHBondContact O-N 3.37Å; A391-R393 PolarHBondContact O-N 2.76Å; R393-A396 PolarHBondContact O-N 3.26Å; R393-L397 HydrophobicContact CG-CD1 4.33Å; R393-L397 WeakPolarHBondContact O-CG 3.25Å; R393-L397 PolarHBondContact O-N 3.35Å
394M80.8Confident80.9Confident100 Ų100100 Ų10049%0.49351%0.508SS..Hα-helixtrans-65.5-37.3176.8-83.1-110.1-90.100112.4E390 A391 D392 L397 R398E390-M394 WeakPolarHBondContact O-CB 3.28Å; E390-M394 WeakPolarHBondContact O-CG 3.37Å; E390-M394 PolarHBondContact O-N 3.17Å; A391-M394 PolarHBondContact O-N 2.89Å; D392-M394 PolarHBondContact O-N 3.44Å; M394-L397 PolarHBondContact O-N 3.34Å; M394-R398 WeakPolarHBondContact O-CG 3.45Å; M394-R398 PolarHBondContact O-N 2.95Å
395A83.4Confident80.5Confident55 Ų55104.2 Ų104.246%0.45552%0.519SS..Hα-helixtrans-64.7-44.9173.300000111.5A391 D392 L397 R398 A399A391-A395 PolarHBondContact O-N 3.3Å; D392-A395 PolarHBondContact O-N 3.48Å; A395-L397 VanDerWaalsContact C-N 3.34Å; A395-L397 PolarHBondContact O-N 2.95Å; A395-R398 PolarHBondContact O-N 3.37Å; A395-A399 PolarHBondContact O-N 2.86Å; A395-A399 VanDerWaalsContact O-N 3.09Å
396A78.6Confident80.2Confident63 Ų63105.6 Ų105.652%0.52153%0.526SS..Hα-helixtrans-62.7-37.1176.600000113.1D392 R393 K400D392-A396 PolarHBondContact O-N 2.81Å; R393-A396 PolarHBondContact O-N 3.26Å; A396-K400 PolarHBondContact O-N 3.03Å; A396-K400 VanDerWaalsContact O-N 3.1Å
397L81.2Confident79.8Confident88 Ų88105.1 Ų105.146%0.46152%0.522SS..Hα-helixtrans-65.3-46175.8-77.4169.5000112.3R393 M394 A395 A399 K400 E401R393-L397 HydrophobicContact CG-CD1 4.33Å; R393-L397 WeakPolarHBondContact O-CG 3.25Å; R393-L397 PolarHBondContact O-N 3.35Å; M394-L397 PolarHBondContact O-N 3.34Å; A395-L397 VanDerWaalsContact C-N 3.34Å; A395-L397 PolarHBondContact O-N 2.95Å; L397-A399 VanDerWaalsContact C-N 3.34Å; L397-A399 PolarHBondContact O-N 3.5Å; L397-K400 WeakPolarHBondContact O-CB 3.4Å; L397-K400 PolarHBondContact O-N 2.85Å; L397-K400 VanDerWaalsContact O-N 3.13Å; L397-E401 PolarHBondContact O-N 3.49Å
398R83.2Confident79.4Confident149 Ų149103.4 Ų103.456%0.56252%0.519SS*.Hα-helixtrans-62.1-41.8176.6-66.9-179.5-143.3141.27.3112M394 A395 K400 E401 E402M394-R398 WeakPolarHBondContact O-CG 3.45Å; M394-R398 PolarHBondContact O-N 2.95Å; A395-R398 PolarHBondContact O-N 3.37Å; R398-K400 PolarHBondContact O-N 3.43Å; R398-E401 PolarHBondContact O-N 3.03Å; R398-E402 WeakPolarHBondContact O-CB 3.26Å; R398-E402 PolarHBondContact O-N 3.35Å
399A79.6Confident78.7Confident53 Ų53101.2 Ų101.244%0.43852%0.517SS..Hα-helixtrans-61-33.9175.900000112.4A395 L397 L403A395-A399 PolarHBondContact O-N 2.86Å; A395-A399 VanDerWaalsContact O-N 3.09Å; L397-A399 VanDerWaalsContact C-N 3.34Å; L397-A399 PolarHBondContact O-N 3.5Å; A399-L403 WeakPolarHBondContact O-CG 3.49Å; A399-L403 PolarHBondContact O-N 3.18Å
400K78.5Confident78Confident105 Ų105103.4 Ų103.446%0.45752%0.524SS..Hα-helixtrans-68.4-48.6172178-177.2172.6-72.60112.1A396 L397 R398 E402 L403 E404A396-K400 PolarHBondContact O-N 3.03Å; A396-K400 VanDerWaalsContact O-N 3.1Å; L397-K400 WeakPolarHBondContact O-CB 3.4Å; L397-K400 PolarHBondContact O-N 2.85Å; L397-K400 VanDerWaalsContact O-N 3.13Å; R398-K400 PolarHBondContact O-N 3.43Å; K400-E402 VanDerWaalsContact C-N 3.27Å; K400-E402 PolarHBondContact O-N 3.45Å; K400-L403 PolarHBondContact O-N 3.31Å; K400-E404 WeakPolarHBondContact CE-OE1 3.26Å; K400-E404 IonicContact NZ-OE1 3.84Å; K400-E404 PolarHBondContact NZ-OE1 3.49Å; K400-E404 IonicContact NZ-OE2 3.09Å; K400-E404 PolarHBondContact NZ-OE2 3.11Å; K400-E404 PolarHBondContact O-N 2.9Å
401E78.9Confident77.5Confident128 Ų128102.4 Ų102.460%0.59852%0.522SS*.Hα-helixtrans-60-38.5178.9-70.2-178.4140.200111.9L397 R398 E404 R405L397-E401 PolarHBondContact O-N 3.49Å; R398-E401 PolarHBondContact O-N 3.03Å; E401-E404 PolarHBondContact O-N 2.91Å; E401-R405 WeakPolarHBondContact O-CB 3.44Å; E401-R405 PolarHBondContact O-N 2.95Å
402E77.9Confident76.8Confident132 Ų132104.6 Ų104.662%0.61752%0.52SS*.Hα-helixtrans-69.1-35.1179.7-164.2154.1-134.900112.3R398 K400 Q406R398-E402 WeakPolarHBondContact O-CB 3.26Å; R398-E402 PolarHBondContact O-N 3.35Å; K400-E402 VanDerWaalsContact C-N 3.27Å; K400-E402 PolarHBondContact O-N 3.45Å; E402-Q406 WeakPolarHBondContact O-CG 3.48Å; E402-Q406 PolarHBondContact O-N 3.29Å
403L74.4Confident76.2Confident114 Ų114103.4 Ų103.460%0.59752%0.52SS*.Hα-helixtrans-68.2-43.4169.6-75.4167.3000112.5A399 K400 R405 Q406 A407A399-L403 WeakPolarHBondContact O-CG 3.49Å; A399-L403 PolarHBondContact O-N 3.18Å; K400-L403 PolarHBondContact O-N 3.31Å; L403-R405 VanDerWaalsContact C-N 3.28Å; L403-R405 PolarHBondContact O-N 3.39Å; L403-Q406 PolarHBondContact O-N 3.11Å; L403-A407 PolarHBondContact O-N 3.27Å; L403-A407 VanDerWaalsContact O-N 3.09Å
404E73.2Confident75Confident94 Ų94102.6 Ų102.644%0.43952%0.523SS..Hα-helixtrans-63.3-36.3176.9-75.8175.5145.800111.7K400 E401 A407 V408K400-E404 WeakPolarHBondContact CE-OE1 3.26Å; K400-E404 IonicContact NZ-OE1 3.84Å; K400-E404 PolarHBondContact NZ-OE1 3.49Å; K400-E404 IonicContact NZ-OE2 3.09Å; K400-E404 PolarHBondContact NZ-OE2 3.11Å; K400-E404 PolarHBondContact O-N 2.9Å; E401-E404 PolarHBondContact O-N 2.91Å; E404-A407 PolarHBondContact O-N 3.14Å; E404-V408 WeakPolarHBondContact O-CG2 3.48Å; E404-V408 PolarHBondContact O-N 3.4Å
405R77.4Confident74.1Confident186 Ų186103.7 Ų103.770%0.70253%0.527SS*.Hα-helixtrans-65.7-41.9175.9-159.1175.1-168-146.32.1112.4E401 L403 A407 V408 D409E401-R405 WeakPolarHBondContact O-CB 3.44Å; E401-R405 PolarHBondContact O-N 2.95Å; L403-R405 VanDerWaalsContact C-N 3.28Å; L403-R405 PolarHBondContact O-N 3.39Å; R405-A407 VanDerWaalsContact C-N 3.33Å; R405-A407 PolarHBondContact O-N 3.11Å; R405-V408 PolarHBondContact O-N 2.83Å; R405-D409 PolarHBondContact O-N 2.83Å; R405-D409 VanDerWaalsContact O-N 3.13Å
406Q75.3Confident73.3Confident124 Ų124108 Ų10858%0.57954%0.538SS*.Hα-helixtrans-61.5-40.7174.1-71.4171.228.500111.8E402 L403 Q410E402-Q406 WeakPolarHBondContact O-CG 3.48Å; E402-Q406 PolarHBondContact O-N 3.29Å; L403-Q406 PolarHBondContact O-N 3.11Å; Q406-Q410 WeakPolarHBondContact O-CB 3.37Å; Q406-Q410 PolarHBondContact O-N 2.9Å; Q406-Q410 VanDerWaalsContact O-N 3.13Å
407A71.4Confident72.5Confident45 Ų45110.3 Ų110.337%0.37254%0.541SS..Hα-helixtrans-64.5-41.1175.700000112.6L403 E404 R405 Q410 I411L403-A407 PolarHBondContact O-N 3.27Å; L403-A407 VanDerWaalsContact O-N 3.09Å; E404-A407 PolarHBondContact O-N 3.14Å; R405-A407 VanDerWaalsContact C-N 3.33Å; R405-A407 PolarHBondContact O-N 3.11Å; A407-Q410 PolarHBondContact O-N 2.96Å; A407-I411 WeakPolarHBondContact O-CG1 3.44Å; A407-I411 PolarHBondContact O-N 3.18Å; A407-I411 VanDerWaalsContact O-N 3.12Å
408V74.6Confident71.7Confident73 Ų73109.1 Ų109.144%0.44254%0.543SS..Hα-helixtrans-63.4-42.3178165.60000112.3E404 R405 Q410 I411 K412E404-V408 WeakPolarHBondContact O-CG2 3.48Å; E404-V408 PolarHBondContact O-N 3.4Å; R405-V408 PolarHBondContact O-N 2.83Å; V408-Q410 VanDerWaalsContact C-N 3.34Å; V408-I411 PolarHBondContact O-N 3.14Å; V408-K412 PolarHBondContact O-N 3.31Å
409D72.4Confident71Confident82 Ų82105 Ų10544%0.43954%0.541SS..Hα-helixtrans-73.2-28179-69.8-25.9000112.2R405 K412 S413R405-D409 PolarHBondContact O-N 2.83Å; R405-D409 VanDerWaalsContact O-N 3.13Å; D409-K412 IonicContact OD1-NZ 3.94Å; D409-K412 PolarHBondContact OD1-NZ 3.23Å; D409-S413 PolarHBondContact O-N 2.85Å
410Q68.1Low70.4Confident143 Ų143108.5 Ų108.567%0.66855%0.548SS*.Hα-helixtrans-66.4-34.8170.9-1651723300112.6Q406 A407 V408Q406-Q410 WeakPolarHBondContact O-CB 3.37Å; Q406-Q410 PolarHBondContact O-N 2.9Å; Q406-Q410 VanDerWaalsContact O-N 3.13Å; A407-Q410 PolarHBondContact O-N 2.96Å; V408-Q410 VanDerWaalsContact C-N 3.34Å
411I68.9Low69.5Low97 Ų97109.2 Ų109.250%0.49756%0.556SS.*Hα-helixtrans-67.2-48175.3-69.8164.8000111.1A407 V408 S413 Q414 E415A407-I411 WeakPolarHBondContact O-CG1 3.44Å; A407-I411 PolarHBondContact O-N 3.18Å; A407-I411 VanDerWaalsContact O-N 3.12Å; V408-I411 PolarHBondContact O-N 3.14Å; I411-S413 PolarHBondContact O-N 3.14Å; I411-Q414 WeakPolarHBondContact O-CA 3.42Å; I411-Q414 WeakPolarHBondContact O-CB 3.39Å; I411-Q414 PolarHBondContact O-N 3.44Å; I411-E415 PolarHBondContact O-N 3.03Å; I411-E415 VanDerWaalsContact O-N 3.16Å
412K68.9Low69Low104 Ų104105.9 Ų105.945%0.45255%0.551SS.*Hα-helixtrans-56.9-35.2178.2-65.7170.4-165.6157.70112.6V408 D409 Q414 E415 Q416V408-K412 PolarHBondContact O-N 3.31Å; D409-K412 IonicContact OD1-NZ 3.94Å; D409-K412 PolarHBondContact OD1-NZ 3.23Å; K412-Q414 PolarHBondContact O-N 2.72Å; K412-E415 PolarHBondContact O-N 3.36Å; K412-Q416 PolarHBondContact O-N 3.29Å
413S68.1Low68.7Low71 Ų71106.3 Ų106.350%0.49755%0.553SS.*Hα-helixtrans-66.9-22.6176.1-171.60000113.5D409 I411 L417D409-S413 PolarHBondContact O-N 2.85Å; I411-S413 PolarHBondContact O-N 3.14Å; S413-L417 WeakPolarHBondContact O-CD1 3.39Å
414Q59.1Low68.3Low148 Ų148108.7 Ų108.769%0.69256%0.555SS**Hα-helixtrans-83.5-37.6171.5-68.4-170.1-24.400111.9I411 K412 Q416 L417 A418I411-Q414 WeakPolarHBondContact O-CA 3.42Å; I411-Q414 WeakPolarHBondContact O-CB 3.39Å; I411-Q414 PolarHBondContact O-N 3.44Å; K412-Q414 PolarHBondContact O-N 2.72Å; Q414-Q416 VanDerWaalsContact C-N 3.27Å; Q414-Q416 PolarHBondContact O-N 2.9Å; Q414-L417 PolarHBondContact O-N 2.9Å; Q414-A418 PolarHBondContact O-N 2.95Å
415E63.6Low68Low124 Ų124108.5 Ų108.558%0.57956%0.56SS**Hα-helixtrans-60.5-35.4178.5-66-178.4132.300112.4I411 K412 A418 A419I411-E415 PolarHBondContact O-N 3.03Å; I411-E415 VanDerWaalsContact O-N 3.16Å; K412-E415 PolarHBondContact O-N 3.36Å; E415-A418 PolarHBondContact O-N 3.17Å; E415-A419 PolarHBondContact O-N 2.92Å
416Q64.8Low67.5Low146 Ų146102.2 Ų102.268%0.68255%0.548SS*.Hα-helixtrans-65.4-40.3176.4-72.2-172.5-40.700113.4K412 Q414 A418 A419 E420K412-Q416 PolarHBondContact O-N 3.29Å; Q414-Q416 VanDerWaalsContact C-N 3.27Å; Q414-Q416 PolarHBondContact O-N 2.9Å; Q416-A418 VanDerWaalsContact C-N 3.29Å; Q416-A418 PolarHBondContact O-N 3.33Å; Q416-A419 PolarHBondContact O-N 3.44Å; Q416-E420 PolarHBondContact O-N 2.94Å
417L62.5Low67.3Low111 Ų111102.7 Ų102.758%0.58155%0.548SS*.Hα-helixtrans-66.6-30.9175.5-87.586.1000112.4S413 Q414 A419 L421S413-L417 WeakPolarHBondContact O-CD1 3.39Å; Q414-L417 PolarHBondContact O-N 2.9Å; L417-A419 VanDerWaalsContact C-N 3.31Å; L417-L421 PolarHBondContact O-N 3.35Å
418A64.4Low66.7Low62 Ų62105.5 Ų105.551%0.51256%0.556SS.*Hα-helixtrans-67.7-32175.900000112.3Q414 E415 Q416 A422Q414-A418 PolarHBondContact O-N 2.95Å; E415-A418 PolarHBondContact O-N 3.17Å; Q416-A418 VanDerWaalsContact C-N 3.29Å; Q416-A418 PolarHBondContact O-N 3.33Å; A418-A422 PolarHBondContact O-N 2.74Å
419A68.3Low66.2Low62 Ų62104.4 Ų104.451%0.51256%0.555SS.*Hα-helixtrans-69.3-45.1179.100000112.9E415 Q416 L417 L421 A422 E423E415-A419 PolarHBondContact O-N 2.92Å; Q416-A419 PolarHBondContact O-N 3.44Å; L417-A419 VanDerWaalsContact C-N 3.31Å; A419-L421 VanDerWaalsContact C-N 3.34Å; A419-L421 PolarHBondContact O-N 2.95Å; A419-A422 WeakPolarHBondContact O-CB 3.47Å; A419-A422 PolarHBondContact O-N 2.75Å; A419-E423 PolarHBondContact O-N 2.9Å
420E67.5Low66.2Low128 Ų128105.9 Ų105.960%0.59856%0.562SS**Hα-helixtrans-62.2-41177.6-68.3-170.3137.800111.8Q416 A422 E423 Y424Q416-E420 PolarHBondContact O-N 2.94Å; E420-A422 VanDerWaalsContact C-N 3.28Å; E420-A422 PolarHBondContact O-N 3.1Å; E420-E423 PolarHBondContact O-N 3.09Å; E420-Y424 VanDerWaalsContact O-CD2 3.3Å; E420-Y424 WeakPolarHBondContact O-CD2 3.3Å; E420-Y424 PolarHBondContact O-N 3.27Å
421L60.4Low65.9Low119 Ų119105.1 Ų105.162%0.62356%0.562SS**Hα-helixtrans-61.4-35.1175.9-77.8167.3000112.6L417 A419 T425L417-L421 PolarHBondContact O-N 3.35Å; A419-L421 VanDerWaalsContact C-N 3.34Å; A419-L421 PolarHBondContact O-N 2.95Å; L421-T425 WeakPolarHBondContact O-CB 3.45Å; L421-T425 PolarHBondContact O-N 3.28Å; L421-T425 VanDerWaalsContact O-N 3.15Å; L421-T425 PolarHBondContact O-OG1 2.9Å
422A66.9Low65.6Low58 Ų58105.8 Ų105.848%0.47956%0.563SS.*Hα-helixtrans-67.7-38.8175.100000112.3A418 A419 E420 T425 A426A418-A422 PolarHBondContact O-N 2.74Å; A419-A422 WeakPolarHBondContact O-CB 3.47Å; A419-A422 PolarHBondContact O-N 2.75Å; E420-A422 VanDerWaalsContact C-N 3.28Å; E420-A422 PolarHBondContact O-N 3.1Å; A422-T425 PolarHBondContact O-N 3.46Å; A422-A426 PolarHBondContact O-N 2.71Å
423E72.2Confident65.2Low141 Ų141104.2 Ų104.266%0.65956%0.557SS**Hα-helixtrans-65.2-45.2178.8-167.7-177.7163.900112A419 E420 T425 A426 K427A419-E423 PolarHBondContact O-N 2.9Å; E420-E423 PolarHBondContact O-N 3.09Å; E423-T425 VanDerWaalsContact C-N 3.3Å; E423-T425 PolarHBondContact O-N 2.93Å; E423-A426 PolarHBondContact O-N 2.91Å; E423-K427 PolarHBondContact O-N 3.38Å
424Y67Low64.8Low164 Ų164103.9 Ų103.964%0.64356%0.559SS**Hα-helixtrans-62.1-37.5173.9-77.2-72.5000112.3E420 K427 I428E420-Y424 VanDerWaalsContact O-CD2 3.3Å; E420-Y424 WeakPolarHBondContact O-CD2 3.3Å; E420-Y424 PolarHBondContact O-N 3.27Å; Y424-K427 PolarHBondContact O-N 2.9Å; Y424-I428 WeakPolarHBondContact O-CG1 3.33Å; Y424-I428 PolarHBondContact O-N 2.86Å; Y424-I428 VanDerWaalsContact O-N 3.1Å
425T66.8Low64.7Low91 Ų91103.2 Ų103.256%0.55855%0.55SS*.Hα-helixtrans-65-44.3177.1-56.40000111.6L421 A422 E423 K427 I428 A429L421-T425 WeakPolarHBondContact O-CB 3.45Å; L421-T425 PolarHBondContact O-N 3.28Å; L421-T425 VanDerWaalsContact O-N 3.15Å; L421-T425 PolarHBondContact O-OG1 2.9Å; A422-T425 PolarHBondContact O-N 3.46Å; E423-T425 VanDerWaalsContact C-N 3.3Å; E423-T425 PolarHBondContact O-N 2.93Å; T425-K427 VanDerWaalsContact C-N 3.26Å; T425-K427 PolarHBondContact O-N 3.33Å; T425-I428 PolarHBondContact O-N 3.29Å; T425-A429 PolarHBondContact O-N 2.93Å
426A66.3Low64.4Low54 Ų54103.4 Ų103.445%0.44655%0.545SS..Hα-helixtrans-62.6-32.917500000112.7A422 E423 A429 L430A422-A426 PolarHBondContact O-N 2.71Å; E423-A426 PolarHBondContact O-N 2.91Å; A426-A429 PolarHBondContact O-N 3.24Å; A426-L430 PolarHBondContact O-N 2.92Å
427K70.5Confident64.2Low134 Ų134102.5 Ų102.558%0.58354%0.535SS*.Hα-helixtrans-72.3-31.7177.4-161168.8-169.6165.20113.3E423 Y424 T425E423-K427 PolarHBondContact O-N 3.38Å; Y424-K427 PolarHBondContact O-N 2.9Å; T425-K427 VanDerWaalsContact C-N 3.26Å; T425-K427 PolarHBondContact O-N 3.33Å
428I60.5Low63.9Low103 Ų103104.6 Ų104.653%0.52854%0.54SS..Hα-helixtrans-69.2-47.2168.8-66.4166.3000109.4Y424 T425 L430 L431 E432Y424-I428 WeakPolarHBondContact O-CG1 3.33Å; Y424-I428 PolarHBondContact O-N 2.86Å; Y424-I428 VanDerWaalsContact O-N 3.1Å; T425-I428 PolarHBondContact O-N 3.29Å; I428-L430 VanDerWaalsContact C-N 3.31Å; I428-L430 PolarHBondContact O-N 3.09Å; I428-L431 PolarHBondContact O-N 2.92Å; I428-E432 HydrophobicContact CG2-CG 4.49Å; I428-E432 PolarHBondContact O-N 3.48Å
429A64Low63.3Low51 Ų51106.9 Ų106.942%0.42154%0.54SS..Hα-helixtrans-55.7-42.6178.100000112.2T425 A426 L431 E432 E433T425-A429 PolarHBondContact O-N 2.93Å; A426-A429 PolarHBondContact O-N 3.24Å; A429-L431 VanDerWaalsContact C-N 3.32Å; A429-L431 PolarHBondContact O-N 2.86Å; A429-E432 CarbonylContact O-C 3.12Å; A429-E432 PolarHBondContact O-N 3.5Å; A429-E433 WeakPolarHBondContact O-CB 3.31Å; A429-E433 PolarHBondContact O-N 3.46Å
430L71.4Confident62.6Low113 Ų113105.3 Ų105.359%0.59252%0.523SS*.Hα-helixtrans-66-26.7176.3-80.9167000114.6A426 I428 A434A426-L430 PolarHBondContact O-N 2.92Å; I428-L430 VanDerWaalsContact C-N 3.31Å; I428-L430 PolarHBondContact O-N 3.09Å; L430-A434 WeakPolarHBondContact O-CB 3.26Å; L430-A434 PolarHBondContact O-N 2.94Å
431L61.5Low62.1Low127 Ų127106.7 Ų106.767%0.66553%0.529SS*.Hα-helixtrans-79.1-41172.8-71.7170000110.9I428 A429 E433 A434 R435I428-L431 PolarHBondContact O-N 2.92Å; A429-L431 VanDerWaalsContact C-N 3.32Å; A429-L431 PolarHBondContact O-N 2.86Å; L431-E433 PolarHBondContact O-N 2.77Å; L431-A434 PolarHBondContact O-N 2.6Å; L431-R435 PolarHBondContact O-N 2.98Å
432E62.3Low61.8Low111 Ų111106.6 Ų106.652%0.51953%0.534SS..Hα-helixtrans-64.2-28.3169.5-70.6-149.5111.900112.1I428 A429 R435 R436I428-E432 HydrophobicContact CG2-CG 4.49Å; I428-E432 PolarHBondContact O-N 3.48Å; A429-E432 CarbonylContact O-C 3.12Å; A429-E432 PolarHBondContact O-N 3.5Å; E432-R435 CarbonylContact O-C 3.48Å; E432-R435 WeakPolarHBondContact O-CB 3.49Å; E432-R435 IonicContact OE1-NH1 3Å; E432-R436 WeakPolarHBondContact O-CA 3.23Å; E432-R436 WeakPolarHBondContact O-CB 3.4Å; E432-R436 PolarHBondContact O-N 2.88Å
433E62Low61Low70 Ų70111.3 Ų111.333%0.32755%0.546SS..Hα-helixtrans-88.2-18176.6-152.1-163.5168.400112.8A429 L431 R436 R437A429-E433 WeakPolarHBondContact O-CB 3.31Å; A429-E433 PolarHBondContact O-N 3.46Å; L431-E433 PolarHBondContact O-N 2.77Å; E433-R436 HydrophobicContact CG-CB 4.49Å; E433-R436 PolarHBondContact O-N 3.42Å; E433-R437 HydrophobicContact CG-CG 4.29Å; E433-R437 VanDerWaalsContact O-CB 3.28Å; E433-R437 WeakPolarHBondContact O-CB 3.37Å; E433-R437 WeakPolarHBondContact O-CG 3.49Å; E433-R437 PolarHBondContact O-N 3.39Å; E433-R437 IonicContact OE1-CZ 3.08Å; E433-R437 IonicContact OE1-NE 3.87Å; E433-R437 PolarHBondContact OE1-NE 2.93Å; E433-R437 IonicContact OE1-NH2 2.66Å; E433-R437 PolarHBondContact OE1-NH2 3.47Å; E433-R437 IonicContact OE2-NH2 2.84Å
434A59.8Low60Low64 Ų64112.6 Ų112.653%0.52955%0.552SS.*Hα-helixtrans-71.7-36.8162.500000110.8L430 L431 K438L430-A434 WeakPolarHBondContact O-CB 3.26Å; L430-A434 PolarHBondContact O-N 2.94Å; L431-A434 PolarHBondContact O-N 2.6Å; A434-K438 PolarHBondContact O-N 3.35Å
435R56.3Low59.2Low135 Ų135113.1 Ų113.151%0.50955%0.553SS.*Hα-helixtrans-68.6-41.7164.4172.4-173.9151-121.2-26.4110.9L431 E432 K438 E439L431-R435 PolarHBondContact O-N 2.98Å; E432-R435 CarbonylContact O-C 3.48Å; E432-R435 WeakPolarHBondContact O-CB 3.49Å; E432-R435 IonicContact OE1-NH1 3Å; R435-K438 CarbonylContact O-C 3.59Å; R435-K438 VanDerWaalsContact O-CA 3.3Å; R435-K438 WeakPolarHBondContact O-CA 3.42Å; R435-K438 WeakPolarHBondContact O-CB 3.23Å; R435-K438 PolarHBondContact O-N 3.08Å; R435-E439 IonicContact CZ-OE1 3.21Å; R435-E439 VanDerWaalsContact CZ-OE1 3.24Å; R435-E439 IonicContact CZ-OE2 3.64Å; R435-E439 IonicContact NE-OE1 3.45Å; R435-E439 PolarHBondContact NE-OE1 2.91Å; R435-E439 IonicContact NE-OE2 2.8Å; R435-E439 IonicContact NH2-OE1 3.94Å; R435-E439 PolarHBondContact NH2-OE1 3.36Å; R435-E439 IonicContact NH2-OE2 3.78Å; R435-E439 PolarHBondContact NH2-OE2 3.5Å; R435-E439 VanDerWaalsContact NH2-OE2 3.09Å; R435-E439 WeakPolarHBondContact O-CG 3.41Å; R435-E439 PolarHBondContact O-N 3.2Å
436R57.9Low57.3Low127 Ų127114.8 Ų114.848%0.47955%0.554SS.*Hα-helixtrans-74.8-31-175.2-146.1-166.6166.1-123.8-22.6111E432 E433 K438 E439 D440E432-R436 WeakPolarHBondContact O-CA 3.23Å; E432-R436 WeakPolarHBondContact O-CB 3.4Å; E432-R436 PolarHBondContact O-N 2.88Å; E433-R436 HydrophobicContact CG-CB 4.49Å; E433-R436 PolarHBondContact O-N 3.42Å; R436-K438 PolarHBondContact O-N 3Å; R436-E439 HydrophobicContact CG-CB 4.36Å; R436-E439 CarbonylContact O-C 3.45Å; R436-E439 WeakPolarHBondContact O-CA 3.42Å; R436-E439 WeakPolarHBondContact O-CB 3.5Å; R436-E439 PolarHBondContact O-N 3.41Å; R436-D440 WeakPolarHBondContact CD-OD2 3.5Å; R436-D440 WeakPolarHBondContact CG-OD2 3.32Å; R436-D440 IonicContact CZ-OD1 3.86Å; R436-D440 IonicContact CZ-OD2 3.53Å; R436-D440 IonicContact NE-OD1 2.73Å; R436-D440 PolarHBondContact NE-OD1 2.93Å; R436-D440 IonicContact NE-OD2 2.66Å; R436-D440 PolarHBondContact NE-OD2 2.96Å; R436-D440 IonicContact NH1-OD1 2.99Å; R436-D440 IonicContact NH1-OD2 3.16Å; R436-D440 PolarHBondContact NH1-OD2 2.68Å; R436-D440 IonicContact NH2-OD1 3.21Å; R436-D440 PolarHBondContact NH2-OD1 2.86Å; R436-D440 IonicContact NH2-OD2 3.89Å; R436-D440 PolarHBondContact NH2-OD2 3.24Å; R436-D440 VanDerWaalsContact O-CA 3.25Å; R436-D440 WeakPolarHBondContact O-CA 3.34Å; R436-D440 WeakPolarHBondContact O-CB 3.44Å; R436-D440 VanDerWaalsContact O-CG 3.22Å; R436-D440 PolarHBondContact O-N 3.42Å
437R59.9Low54.7Low127 Ų127118 Ų11848%0.47956%0.559SS.*Hα-helixtrans-78.4-0.4165.5-64.3178.3-163.4-173.86.5113.7E433 D440 E441E433-R437 HydrophobicContact CG-CG 4.29Å; E433-R437 VanDerWaalsContact O-CB 3.28Å; E433-R437 WeakPolarHBondContact O-CB 3.37Å; E433-R437 WeakPolarHBondContact O-CG 3.49Å; E433-R437 PolarHBondContact O-N 3.39Å; E433-R437 IonicContact OE1-CZ 3.08Å; E433-R437 IonicContact OE1-NE 3.87Å; E433-R437 PolarHBondContact OE1-NE 2.93Å; E433-R437 IonicContact OE1-NH2 2.66Å; E433-R437 PolarHBondContact OE1-NH2 3.47Å; E433-R437 IonicContact OE2-NH2 2.84Å; R437-D440 WeakPolarHBondContact CA-O 3.49Å; R437-E441 WeakPolarHBondContact O-CG 3.37Å
438K57.1Low52.7Low155 Ų155121.5 Ų121.567%0.67457%0.569SS**Hα-helixtrans-87.9-14.5155.5-87-86.4160.7-111.90112.3A434 R435 R436 E441A434-K438 PolarHBondContact O-N 3.35Å; R435-K438 CarbonylContact O-C 3.59Å; R435-K438 VanDerWaalsContact O-CA 3.3Å; R435-K438 WeakPolarHBondContact O-CA 3.42Å; R435-K438 WeakPolarHBondContact O-CB 3.23Å; R435-K438 PolarHBondContact O-N 3.08Å; R436-K438 PolarHBondContact O-N 3Å; K438-E441 IonicContact NZ-OE2 2.83Å; K438-E441 PolarHBondContact NZ-OE2 2.76Å
439E50Low50.2Low110 Ų110121.3 Ų121.351%0.51458%0.583SS.*Hα-helixtrans-103.4-13.2171.7-60.2166.4178.500112.5R435 R436R435-E439 IonicContact CZ-OE1 3.21Å; R435-E439 VanDerWaalsContact CZ-OE1 3.24Å; R435-E439 IonicContact CZ-OE2 3.64Å; R435-E439 IonicContact NE-OE1 3.45Å; R435-E439 PolarHBondContact NE-OE1 2.91Å; R435-E439 IonicContact NE-OE2 2.8Å; R435-E439 IonicContact NH2-OE1 3.94Å; R435-E439 PolarHBondContact NH2-OE1 3.36Å; R435-E439 IonicContact NH2-OE2 3.78Å; R435-E439 PolarHBondContact NH2-OE2 3.5Å; R435-E439 VanDerWaalsContact NH2-OE2 3.09Å; R435-E439 WeakPolarHBondContact O-CG 3.41Å; R435-E439 PolarHBondContact O-N 3.2Å; R436-E439 HydrophobicContact CG-CB 4.36Å; R436-E439 CarbonylContact O-C 3.45Å; R436-E439 WeakPolarHBondContact O-CA 3.42Å; R436-E439 WeakPolarHBondContact O-CB 3.5Å; R436-E439 PolarHBondContact O-N 3.41Å
440D55.3Low47.5Very low30 Ų30127.1 Ų127.116%0.1660%0.599CS.*  trans-146.758.1-166-61.8-22.9000109.2R436 R437 V442R436-D440 WeakPolarHBondContact CD-OD2 3.5Å; R436-D440 WeakPolarHBondContact CG-OD2 3.32Å; R436-D440 IonicContact CZ-OD1 3.86Å; R436-D440 IonicContact CZ-OD2 3.53Å; R436-D440 IonicContact NE-OD1 2.73Å; R436-D440 PolarHBondContact NE-OD1 2.93Å; R436-D440 IonicContact NE-OD2 2.66Å; R436-D440 PolarHBondContact NE-OD2 2.96Å; R436-D440 IonicContact NH1-OD1 2.99Å; R436-D440 IonicContact NH1-OD2 3.16Å; R436-D440 PolarHBondContact NH1-OD2 2.68Å; R436-D440 IonicContact NH2-OD1 3.21Å; R436-D440 PolarHBondContact NH2-OD1 2.86Å; R436-D440 IonicContact NH2-OD2 3.89Å; R436-D440 PolarHBondContact NH2-OD2 3.24Å; R436-D440 VanDerWaalsContact O-CA 3.25Å; R436-D440 WeakPolarHBondContact O-CA 3.34Å; R436-D440 WeakPolarHBondContact O-CB 3.44Å; R436-D440 VanDerWaalsContact O-CG 3.22Å; R436-D440 PolarHBondContact O-N 3.42Å; R437-D440 WeakPolarHBondContact CA-O 3.49Å; D440-V442 VanDerWaalsContact C-N 3.29Å; D440-V442 HydrophobicContact CB-CG1 3.7Å; D440-V442 WeakPolarHBondContact O-CG1 3.44Å; D440-V442 PolarHBondContact O-N 2.95Å
441E55.7Low44.4Very low156 Ų156128.7 Ų128.773%0.72960%0.603SS**  trans-61.70165.4-70.9-167.343.300107.7R437 K438R437-E441 WeakPolarHBondContact O-CG 3.37Å; K438-E441 IonicContact NZ-OE2 2.83Å; K438-E441 PolarHBondContact NZ-OE2 2.76Å
442V54.8Low42.1Very low117 Ų117127.8 Ų127.871%0.70961%0.614SS**  00049.10000128.8D440D440-V442 VanDerWaalsContact C-N 3.29Å; D440-V442 HydrophobicContact CB-CG1 3.7Å; D440-V442 WeakPolarHBondContact O-CG1 3.44Å; D440-V442 PolarHBondContact O-N 2.95Å
443E49.1Very low40.4Very low157 Ų157130.8 Ų130.873%0.73463%0.628SS**  000-45.1-173.7-121.200132.2
444E53Low39.4Very low169 Ų169134.2 Ų134.279%0.7965%0.649SS**  000-65.5-152.8-70.500129.5
445W48.3Very low38.9Very low174 Ų174138.1 Ų138.166%0.65966%0.661SS**  00052.2-108.5000127.5H447W445-H447 AromaticContact CE3-CE1 3.67Å; W445-H447 AromaticContact CZ3-CE1 3.46Å; W445-H447 VanDerWaalsContact CZ3-CE1 3.46Å; W445-H447 WeakPolarHBondContact CZ3-CE1 3.42Å; W445-H447 AromaticContact CZ3-NE2 3.7Å
446Q27.3Very low38.7Very low127 Ų127139 Ų13959%0.59367%0.674SS**  000-104.8-46.5-5900126.3R448Q446-R448 VanDerWaalsContact C-NH2 3.32Å; Q446-R448 PolarHBondContact O-NH1 2.67Å; Q446-R448 PolarHBondContact O-NH2 3.39Å
447H11.6Very low38.5Very low120 Ų120139.7 Ų139.756%0.55669%0.693SS**  000-19.7-75.1000124.9W445W445-H447 AromaticContact CE3-CE1 3.67Å; W445-H447 AromaticContact CZ3-CE1 3.46Å; W445-H447 VanDerWaalsContact CZ3-CE1 3.46Å; W445-H447 WeakPolarHBondContact CZ3-CE1 3.42Å; W445-H447 AromaticContact CZ3-NE2 3.7Å
448R28.8Very low38.1Very low209 Ų209142.7 Ų142.779%0.78971%0.709SS**  000-4988.5-148.7146.410.7122.7Q446Q446-R448 VanDerWaalsContact C-NH2 3.32Å; Q446-R448 PolarHBondContact O-NH1 2.67Å; Q446-R448 PolarHBondContact O-NH2 3.39Å
449A8.2Very low37.2Very low99 Ų99141.2 Ų141.282%0.81871%0.714SS**  00000000123.9
450K6.9Very low37Very low173 Ų173142.1 Ų142.175%0.75272%0.716SS**  000-133.872.2-114.178.50123.6
451E6.6Very low36.2Very low145 Ų145147.9 Ų147.968%0.67874%0.742SS**  00064.6-63.5-75.400124.3
452A13.9Very low35.2Very low109 Ų109147.5 Ų147.590%0.90174%0.74SS**  00000000123.2
453Q26.5Very low34.3Very low174 Ų174149.9 Ų149.981%0.81375%0.748SS**  000-125.3179.9-98.900124.5
454D41Very low33.4Very low142 Ų142150.7 Ų150.776%0.75975%0.751SS**  000-54.4-24.2000128.3
455D49.5Very low32.2Very low146 Ų146150.1 Ų150.178%0.78175%0.753SS**  000-165.515.2000112.4
456L51.3Low31.3Very low152 Ų152147.8 Ų147.880%0.79676%0.757SS**  000-169.147.2000116.6
457V54.3Low31.4Very low142 Ų142149.3 Ų149.386%0.86177%0.766SS**  00073.90000124
458K50.6Low32.2Very low190 Ų190150 Ų15083%0.82678%0.779SS**  000-140.3-178.2-177179.90116.9
459T38.5Very low32Very low125 Ų125144.6 Ų144.677%0.76778%0.779SS**  000-26.70000117.1
460K46.6Very low34.1Very low128 Ų128145.6 Ų145.656%0.55778%0.778SS**  000-169.4-158.7160-60.30119.2E462K460-E462 WeakPolarHBondContact CE-OE1 3.29Å; K460-E462 IonicContact NZ-OE1 2.89Å; K460-E462 PolarHBondContact NZ-OE1 2.94Å; K460-E462 IonicContact NZ-OE2 2.77Å; K460-E462 PolarHBondContact NZ-OE2 2.85Å
461E36.7Very low35.8Very low151 Ų151142.9 Ų142.971%0.70678%0.778SS**  000-73.5-26.5-59.500121.6
462E36.5Very low37.6Very low149 Ų149141.2 Ų141.270%0.69678%0.779SS**  000-56.189.2-124.300125.3K460K460-E462 WeakPolarHBondContact CE-OE1 3.29Å; K460-E462 IonicContact NZ-OE1 2.89Å; K460-E462 PolarHBondContact NZ-OE1 2.94Å; K460-E462 IonicContact NZ-OE2 2.77Å; K460-E462 PolarHBondContact NZ-OE2 2.85Å
463L34.8Very low39.1Very low167 Ų167141.8 Ų141.887%0.87477%0.774SS**  000-169.559000124.8
464H30.2Very low40.1Very low173 Ų173139 Ų13980%0.80177%0.771SS**  000-126.667.6000123.4
465L28.8Very low40.4Very low157 Ų157138 Ų13882%0.82277%0.772SS**  000-12171.1000116.4
466V29Very low40.3Very low125 Ų125137 Ų13776%0.75877%0.774SS**  00061.70000118.7
467M28.3Very low39.2Very low159 Ų159134.9 Ų134.978%0.78377%0.767SS**  000-63.917356.100122.5
468T29.1Very low38Very low134 Ų134137.5 Ų137.582%0.82276%0.762SS**  000-18.60000117.6
469A25.3Very low36.8Very low96 Ų96136.1 Ų136.179%0.79376%0.759SS**  0176.9000000120.2
470P51.5Low36.8Very low121 Ų121135.4 Ų135.479%0.78676%0.757SS**  cis-128.40-21.432.4-5.6000113
471P43Very low35.9Very low116 Ų116136.3 Ų136.375%0.75377%0.767SS**  00026.82.6000121.9
472P43.4Very low35.4Very low110 Ų110134 Ų13471%0.71477%0.767SS**  00042.8-17.7000116.8
473P46.8Very low34.9Very low120 Ų120135.5 Ų135.578%0.77977%0.768SS**  000291.6000121.5
474P47.5Very low34.5Very low115 Ų115136.3 Ų136.375%0.74777%0.767SS**  0172.3044.2-22000123.5
475P46.1Very low34.6Very low122 Ų122134.5 Ų134.579%0.79277%0.768SS**  trans-143.7152.6177.243.1-26.6000121.7
476P47.3Very low34.8Very low126 Ų126134.3 Ų134.382%0.81876%0.763SS**  trans-152.1-164.8141.943-24.6000114.6
477V29.3Very low34.9Very low107 Ų107135.9 Ų135.965%0.64876%0.761SS**  cis-153.2-168.42.9-93.90000108.1
478Y28.3Very low35.3Very low196 Ų196133.5 Ų133.577%0.76976%0.761SS**  cis-155.4179.410.1-87-52.3000108.4
479E25.8Very low35.7Very low162 Ų162135 Ų13576%0.75776%0.762SS**  cis89.8150.718.1-60.1-173.784.200118.6
480P38.7Very low36.4Very low110 Ų110139 Ų13971%0.71477%0.765SS**  cis-143.2-163.2-19.234.9-9.7000117.8
481L26.7Very low35.6Very low146 Ų146140 Ų14076%0.76476%0.764SS**  trans84172.6166.5-49.8177.3000119.8
482S27.2Very low35.6Very low103 Ų103142.9 Ų142.972%0.7277%0.767SS**  cis-158.4-1809.961.50000114.6
483Y26.5Very low35.3Very low181 Ų181140.3 Ų140.371%0.7176%0.761SS**  trans-153.7177.7-162.5-23.5-78.9000119.9
484H26.7Very low35.3Very low184 Ų184139.4 Ų139.485%0.85276%0.764SS**  trans103.9148.1159.1-54.3-72.5000123.5
485V31Very low35.1Very low135 Ų135141.5 Ų141.582%0.81876%0.763SS**  trans-169.9177.4-17667.70000117.1
486Q32.8Very low35.3Very low153 Ų153139.8 Ų139.872%0.71575%0.752SS**  trans87.9154.6161.4-76.4175.2-82.100123.1
487E31.3Very low34.7Very low157 Ų157138.7 Ų138.773%0.73474%0.743SS**  cis-178.6176.4-18.9-169161.3-125.900115.3
488S37.1Very low35.2Very low110 Ų110136.2 Ų136.277%0.76974%0.739SS**  trans84.7164.9161.983.20000120.9
489L38.3Very low36.2Very low164 Ų164133.5 Ų133.586%0.85973%0.729SS**  cis-164.1-179.4-6.3-127.7174000112.7
490Q39.1Very low37.3Very low180 Ų180131.6 Ų131.684%0.84173%0.733SS**  trans-152.7139-176.5-98.9-176.4-23.300120.1
491D35.5Very low38.1Very low143 Ų143128 Ų12877%0.76571%0.713SS**  77.2146124-13624000132.2
492E41.8Very low40Very low176 Ų176129.2 Ų129.282%0.82272%0.715SS**  trans48.2160151.4-87.4-76.715700130.3
493G37.6Very low42.1Very low56 Ų56125.1 Ų125.158%0.57769%0.685SS**  trans126.7143.4157.400000125.2
494A47.1Very low44.1Very low102 Ų102119.3 Ų119.384%0.84367%0.671SS**  trans-157-179.7-175.600000122.5
495E42.5Very low45.6Very low158 Ų158113.3 Ų113.374%0.73865%0.65SS**  trans100.70157.1-70.3-62.188.800127.1K27K27-E495 WeakPolarHBondContact CE-O 3.4Å; K27-E495 PolarHBondContact NZ-O 3.33Å
496P49.8Very low46.8Very low86 Ų86114 Ų11456%0.55864%0.644SS**  0-171.5048.3-34.7000122.5K27K27-P496 HydrophobicContact CD-CB 4.39Å
497T36.6Very low47.8Very low103 Ų103109.5 Ų109.563%0.63264%0.638SS**  trans-155.7-180-170.558.50000121
498G38.8Very low49Very low55 Ų55104.8 Ų104.857%0.56762%0.617SS**  trans-168.3172.9173.700000117.1
499Y50.1Low49.9Very low139 Ų139107.6 Ų107.655%0.54561%0.611SS.*  trans-139134.4-161.7-68.8-77.7000123.2M285M285-Y499 HydrophobicContact CE-CD1 4.29Å
500S48.7Very low50.7Low122 Ų122105.8 Ų105.885%0.85360%0.602SS**  trans-147.1167137.3-174.70000107.3
501A55.3Low51.7Low35 Ų35100.8 Ų100.829%0.28958%0.582SS.*  trans-145.1111.1-175.700000116.2M285M285-A501 HydrophobicContact CE-CB 3.58Å; M285-A501 HydrophobicContact CG-CB 4.08Å; M285-A501 HydrophobicContact SD-CB 4Å
502E65.5Low53.3Low171 Ų17197.4 Ų97.480%0.79956%0.558SS**  trans-76149.5138.7-62.2-167.612700108.7
503L73.1Confident54.7Low17 Ų1792.6 Ų92.69%0.08954%0.538CS..  trans-93107.8178-60.5-179.3000108.5I245 I248 M285 H288 S505I245-L503 HydrophobicContact CG2-CD1 4.15Å; I248-L503 HydrophobicContact CD1-CD1 3.63Å; I248-L503 HydrophobicContact CG1-CD1 3.68Å; M285-L503 HydrophobicContact CG-CD2 4.48Å; H288-L503 HydrophobicContact CB-CD1 4.26Å; H288-L503 HydrophobicContact CB-CD2 4.27Å; L503-S505 PolarHBondContact O-N 3.42Å
504S66.6Low56.5Low60 Ų6090.5 Ų90.542%0.4251%0.513SS..  trans-61.6123.3-178.8177.30000110.5M292 E506M292-S504 WeakPolarHBondContact CE-O 3.39Å; S504-E506 PolarHBondContact OG-N 3.17Å
505S59.6Low57.9Low58 Ų5888.6 Ų88.641%0.40649%0.487SS..  trans-101.114171.867.20000112.6L503 I508L503-S505 PolarHBondContact O-N 3.42Å; S505-I508 WeakPolarHBondContact O-CG1 3.39Å
506E55.7Low59.9Low149 Ų14988.1 Ų88.170%0.69648%0.482SS*.THydrogen-bonded Turntrans-84.5137.2-176-65.7-171.9141.400111.8K296 S504K296-E506 WeakPolarHBondContact CE-O 3.31Å; K296-E506 PolarHBondContact NZ-O 3.19Å; S504-E506 PolarHBondContact OG-N 3.17Å
507G54.8Low61.8Low58 Ų5885.5 Ų85.560%0.59846%0.461SS*.THydrogen-bonded Turntrans76.419.5179.200000114.8R509G507-R509 PolarHBondContact O-N 3.2Å
508I55Low64.6Low58 Ų5883.4 Ų83.430%0.29745%0.446SS..  trans-65.3116169.2-62.3175.1000108.8M292 S505M292-I508 HydrophobicContact CE-CD1 4.16Å; M292-I508 HydrophobicContact CE-CG1 3.53Å; M292-I508 HydrophobicContact SD-CD1 3.94Å; M292-I508 HydrophobicContact SD-CG1 3.74Å; S505-I508 WeakPolarHBondContact O-CG1 3.39Å
509R55.6Low67.3Low170 Ų17081.7 Ų81.764%0.64242%0.424SS*.  trans-75.8126.7148.2-66.6-178.2176-171.7-1.5106.4G507 D511G507-R509 PolarHBondContact O-N 3.2Å; R509-D511 PolarHBondContact O-N 3.28Å
510D55.2Low69.4Low126 Ų12675.4 Ų75.467%0.67440%0.4SS*.  trans-76.139.7-179.3-162.420.7000112.2R512D510-R512 VanDerWaalsContact C-N 3.32Å; D510-R512 PolarHBondContact O-N 3.22Å; D510-R512 VanDerWaalsContact O-N 3.07Å; D510-R512 IonicContact OD1-NE 2.86Å
511D60Low71.6Confident75 Ų7570.9 Ų70.940%0.40137%0.37SS..  trans-79.182173.5-95.7-48.6000108.3R509 N513R509-D511 PolarHBondContact O-N 3.28Å; D511-N513 WeakPolarHBondContact CB-ND2 3.43Å; D511-N513 PolarHBondContact O-N 3.4Å; D511-N513 PolarHBondContact OD1-ND2 2.88Å
512R70.6Confident73.4Confident72 Ų7273.4 Ų73.427%0.27238%0.375SS..  trans-68.346.1169.6-65.2-178.1167.2-1331.7112.3E244 D510 E514 E515E244-R512 IonicContact OE1-NH1 2.74Å; E244-R512 IonicContact OE1-NH2 2.6Å; D510-R512 VanDerWaalsContact C-N 3.32Å; D510-R512 PolarHBondContact O-N 3.22Å; D510-R512 VanDerWaalsContact O-N 3.07Å; D510-R512 IonicContact OD1-NE 2.86Å; R512-E514 VanDerWaalsContact C-OE2 3.25Å; R512-E514 WeakPolarHBondContact CA-OE2 3.28Å; R512-E514 PolarHBondContact O-N 2.88Å; R512-E514 VanDerWaalsContact O-N 3.17Å; R512-E515 HydrophobicContact CB-CG 4.15Å; R512-E515 WeakPolarHBondContact CD-OE1 3.27Å; R512-E515 IonicContact CZ-OE1 3.84Å; R512-E515 IonicContact NH1-OE1 2.76Å; R512-E515 PolarHBondContact NH1-OE1 2.94Å; R512-E515 WeakPolarHBondContact O-CB 3.36Å; R512-E515 PolarHBondContact O-N 2.84Å
513N70.8Confident74.7Confident75 Ų7569.8 Ų69.840%0.40136%0.357SS..G310 helixtrans-66.4-17.7-174.2-73.2-33.2000112.5D511 E515 K516D511-N513 WeakPolarHBondContact CB-ND2 3.43Å; D511-N513 PolarHBondContact O-N 3.4Å; D511-N513 PolarHBondContact OD1-ND2 2.88Å; N513-E515 PolarHBondContact O-N 3.08Å; N513-K516 PolarHBondContact O-N 2.9Å; N513-K516 PolarHBondContact OD1-NZ 3.44Å
514E74.3Confident75.8Confident11 Ų1171.1 Ų71.15%0.05136%0.364CS..G310 helixtrans-59-32167.167.7-88.8-145.900113.3L223 Y291 R295 R512 K516 R517L223-E514 HydrophobicContact CD2-CB 3.97Å; Y291-E514 WeakPolarHBondContact CE2-OE1 3.49Å; Y291-E514 PolarHBondContact OH-OE1 2.6Å; R295-E514 IonicContact CZ-OE2 3.71Å; R295-E514 IonicContact NE-OE2 3.98Å; R295-E514 IonicContact NH2-OE1 3.18Å; R295-E514 IonicContact NH2-OE2 2.6Å; R295-E514 PolarHBondContact NH2-OE2 3.37Å; R512-E514 VanDerWaalsContact C-OE2 3.25Å; R512-E514 WeakPolarHBondContact CA-OE2 3.28Å; R512-E514 PolarHBondContact O-N 2.88Å; R512-E514 VanDerWaalsContact O-N 3.17Å; E514-K516 PolarHBondContact O-N 2.71Å; E514-R517 PolarHBondContact O-N 3.33Å
515E77.1Confident77.1Confident63 Ų6374.6 Ų74.629%0.29437%0.374SS..G310 helixtrans-72.6-19.8179.4-63.4-179170.900112.1R512 N513 R569R512-E515 HydrophobicContact CB-CG 4.15Å; R512-E515 WeakPolarHBondContact CD-OE1 3.27Å; R512-E515 IonicContact CZ-OE1 3.84Å; R512-E515 IonicContact NH1-OE1 2.76Å; R512-E515 PolarHBondContact NH1-OE1 2.94Å; R512-E515 WeakPolarHBondContact O-CB 3.36Å; R512-E515 PolarHBondContact O-N 2.84Å; N513-E515 PolarHBondContact O-N 3.08Å; E515-R569 VanDerWaalsContact O-CD 3.24Å; E515-R569 WeakPolarHBondContact O-CD 3.45Å; E515-R569 WeakPolarHBondContact O-CG 3.36Å; E515-R569 PolarHBondContact O-NH1 3.36Å
516K84.5Confident78.7Confident148 Ų14876.3 Ų76.364%0.64337%0.372SS*.G310 helixtrans-89.8-2.1178.4-60.1172.9-168.4155.70113.3N513 E514N513-K516 PolarHBondContact O-N 2.9Å; N513-K516 PolarHBondContact OD1-NZ 3.44Å; E514-K516 PolarHBondContact O-N 2.71Å
517R90.3Very high80.6Confident30 Ų3069.3 Ų69.311%0.11334%0.339CS..  trans-67.3145.7-175.1-67.7-177.176.1-162.84.2112.7E87 D88 E514 Y565 R569E87-R517 PolarHBondContact O-NH1 2.94Å; E87-R517 PolarHBondContact O-NH2 3.41Å; D88-R517 VanDerWaalsContact CB-NH2 3.34Å; D88-R517 IonicContact OD1-NH2 3.7Å; D88-R517 IonicContact OD2-CZ 2.76Å; D88-R517 IonicContact OD2-NE 2.67Å; D88-R517 IonicContact OD2-NH2 3.37Å; D88-R517 PolarHBondContact OD2-NH2 3Å; E514-R517 PolarHBondContact O-N 3.33Å; R517-Y565 HydrophobicContact CB-CD1 3.74Å; R517-Y565 HydrophobicContact CB-CD2 4.23Å; R517-Y565 HydrophobicContact CB-CE1 3.97Å; R517-Y565 HydrophobicContact CB-CE2 4.41Å; R517-Y565 HydrophobicContact CB-CG 3.89Å; R517-Y565 VanDerWaalsContact CZ-OH 3.32Å; R517-Y565 PolarHBondContact NH2-OH 3.4Å; R517-Y565 VanDerWaalsContact O-CB 3.24Å; R517-Y565 WeakPolarHBondContact O-CB 3.37Å; R517-R569 PolarHBondContact O-NH1 2.86Å; R517-R569 PolarHBondContact O-NH2 3.1Å
518I94.1Very high82.5Confident60 Ų6071 Ų7131%0.30833%0.331SS..  trans-130.8155.3174.750.3162.4000107.8E522 K523I518-E522 HydrophobicContact CB-CB 4.18Å; I518-E522 HydrophobicContact CB-CG 4.06Å; I518-E522 HydrophobicContact CD1-CG 4.23Å; I518-E522 HydrophobicContact CG2-CG 4.28Å; I518-K523 HydrophobicContact CD1-CG 3.71Å; I518-K523 HydrophobicContact CG1-CG 3.8Å; I518-K523 VanDerWaalsContact O-CE 3.3Å; I518-K523 WeakPolarHBondContact O-CE 3.08Å
519T95.6Very high84.5Confident18 Ų1875.2 Ų75.211%0.1134%0.343CS..  trans-69.9158.3-176.857.40000111.5D197 A521 E522 K523 D563 Y565D197-T519 HydrophobicContact CB-CG2 4.01Å; D197-T519 WeakPolarHBondContact OD2-CA 3.32Å; D197-T519 WeakPolarHBondContact OD2-CB 3.48Å; T519-A521 PolarHBondContact O-N 3.24Å; T519-E522 CarbonylContact O-C 3.52Å; T519-E522 WeakPolarHBondContact O-CA 3.19Å; T519-E522 PolarHBondContact O-N 2.92Å; T519-E522 WeakPolarHBondContact OG1-CB 3.4Å; T519-E522 PolarHBondContact OG1-N 3.36Å; T519-K523 WeakPolarHBondContact O-CG 3.03Å; T519-K523 PolarHBondContact O-N 3.42Å; T519-D563 HydrophobicContact CG2-CB 4.06Å; T519-Y565 HydrophobicContact CG2-CD2 3.93Å; T519-Y565 HydrophobicContact CG2-CE2 4.07Å
520E95.6Very high86.4Confident8 Ų867.5 Ų67.54%0.03731%0.314CS..Hα-helixtrans-56.4-36.2169.8-171.963.3-159.700110.7K193 I194 D197 E522 K523 N524 V527K193-E520 HydrophobicContact CB-CG 4.28Å; K193-E520 WeakPolarHBondContact CE-OE2 3.29Å; K193-E520 IonicContact NZ-OE1 2.88Å; K193-E520 PolarHBondContact NZ-OE1 3.03Å; K193-E520 IonicContact NZ-OE2 2.65Å; K193-E520 PolarHBondContact NZ-OE2 3.48Å; I194-E520 HydrophobicContact CG1-CG 4.25Å; D197-E520 PolarHBondContact OD2-N 2.95Å; E520-E522 PolarHBondContact O-N 3.36Å; E520-K523 PolarHBondContact O-N 2.89Å; E520-N524 HydrophobicContact CG-CB 4.31Å; E520-N524 WeakPolarHBondContact O-CA 3.39Å; E520-N524 WeakPolarHBondContact O-CB 3.45Å; E520-N524 PolarHBondContact O-N 2.95Å; E520-N524 WeakPolarHBondContact OE1-CB 3.23Å; E520-N524 PolarHBondContact OE1-ND2 2.85Å; E520-V527 HydrophobicContact CG-CG2 4.33Å
521A93.4Very high88.4Confident27 Ų2762.8 Ų62.822%0.22329%0.289CS..Hα-helixtrans-67.4-15.5173.700000114.7T519 V527 Q528 L531T519-A521 PolarHBondContact O-N 3.24Å; A521-V527 HydrophobicContact CB-CG1 4.5Å; A521-Q528 WeakPolarHBondContact O-CB 3.22Å; A521-Q528 VanDerWaalsContact O-CG 3.31Å; A521-Q528 WeakPolarHBondContact O-CG 3.42Å; A521-L531 HydrophobicContact CB-CD1 3.89Å
522E94.1Very high90.1Very high87 Ų8764.7 Ų64.741%0.40730%0.299SS..Hα-helixtrans-100.5-26.9173-173168.9-16500111.7I518 T519 E520 K566I518-E522 HydrophobicContact CB-CB 4.18Å; I518-E522 HydrophobicContact CB-CG 4.06Å; I518-E522 HydrophobicContact CD1-CG 4.23Å; I518-E522 HydrophobicContact CG2-CG 4.28Å; T519-E522 CarbonylContact O-C 3.52Å; T519-E522 WeakPolarHBondContact O-CA 3.19Å; T519-E522 PolarHBondContact O-N 2.92Å; T519-E522 WeakPolarHBondContact OG1-CB 3.4Å; T519-E522 PolarHBondContact OG1-N 3.36Å; E520-E522 PolarHBondContact O-N 3.36Å; E522-K566 VanDerWaalsContact CD-NZ 3.29Å; E522-K566 IonicContact OE1-NZ 2.64Å; E522-K566 PolarHBondContact OE1-NZ 3.15Å; E522-K566 VanDerWaalsContact OE1-NZ 3.16Å; E522-K566 IonicContact OE2-NZ 3.97Å; E522-K566 PolarHBondContact OE2-NZ 2.69Å
523K93.6Very high91.3Very high95 Ų9564.4 Ų64.441%0.41331%0.305SS..Hα-helixtrans-75.2-34.5172-67170.9-178.5171.80113.4D88 I518 T519 E520D88-K523 IonicContact OD2-NZ 3.84Å; D88-K523 PolarHBondContact OD2-NZ 2.89Å; I518-K523 HydrophobicContact CD1-CG 3.71Å; I518-K523 HydrophobicContact CG1-CG 3.8Å; I518-K523 VanDerWaalsContact O-CE 3.3Å; I518-K523 WeakPolarHBondContact O-CE 3.08Å; T519-K523 WeakPolarHBondContact O-CG 3.03Å; T519-K523 PolarHBondContact O-N 3.42Å; E520-K523 PolarHBondContact O-N 2.89Å
524N94.7Very high92.5Very high45 Ų4560.8 Ų60.824%0.24129%0.286CS..  trans-12897.8-159.1-172.9-21.4000111.3E520 R526 V527 Q528E520-N524 HydrophobicContact CG-CB 4.31Å; E520-N524 WeakPolarHBondContact O-CA 3.39Å; E520-N524 WeakPolarHBondContact O-CB 3.45Å; E520-N524 PolarHBondContact O-N 2.95Å; E520-N524 WeakPolarHBondContact OE1-CB 3.23Å; E520-N524 PolarHBondContact OE1-ND2 2.85Å; N524-R526 PolarHBondContact O-N 2.66Å; N524-R526 WeakPolarHBondContact OD1-CB 3.39Å; N524-R526 PolarHBondContact OD1-N 2.86Å; N524-R526 VanDerWaalsContact OD1-N 3.17Å; N524-V527 HydrophobicContact CB-CB 4.23Å; N524-V527 HydrophobicContact CB-CG2 4.24Å; N524-V527 PolarHBondContact O-N 2.89Å; N524-V527 VanDerWaalsContact O-N 3.08Å; N524-V527 PolarHBondContact OD1-N 3.33Å; N524-Q528 PolarHBondContact O-N 3.39Å
525E94Very high93.6Very high133 Ų13362.2 Ų62.262%0.62130%0.297SS*.Hα-helixtrans-54.9-25.4179.7-61.7-175.9179.700114.3R529E525-R529 WeakPolarHBondContact O-CB 3.46Å; E525-R529 WeakPolarHBondContact O-CG 3.34Å; E525-R529 PolarHBondContact O-N 3.44Å; E525-R529 VanDerWaalsContact O-N 3.12Å; E525-R529 PolarHBondContact O-NE 2.97Å; E525-R529 IonicContact OE2-NH2 2.73Å; E525-R529 PolarHBondContact OE2-NH2 3.26Å
526R94.2Very high94.4Very high95 Ų9562.7 Ų62.736%0.35831%0.307SS..Hα-helixtrans-69.1-55176.3-170.2-173.6-174.7-168.81.1109.3E178 N524 Q528 R529 Q530E178-R526 PolarHBondContact O-NH2 2.8Å; E178-R526 IonicContact OE2-NH2 2.9Å; E178-R526 PolarHBondContact OE2-NH2 3.39Å; E178-R526 VanDerWaalsContact OE2-NH2 3.08Å; N524-R526 PolarHBondContact O-N 2.66Å; N524-R526 WeakPolarHBondContact OD1-CB 3.39Å; N524-R526 PolarHBondContact OD1-N 2.86Å; N524-R526 VanDerWaalsContact OD1-N 3.17Å; R526-Q528 VanDerWaalsContact C-N 3.27Å; R526-Q528 PolarHBondContact O-N 2.88Å; R526-R529 PolarHBondContact O-N 2.87Å; R526-Q530 HydrophobicContact CG-CG 4.48Å; R526-Q530 VanDerWaalsContact O-CG 3.27Å; R526-Q530 WeakPolarHBondContact O-CG 3.36Å; R526-Q530 PolarHBondContact O-N 2.95Å
527V94.8Very high94.9Very high1 Ų158.1 Ų58.11%0.00629%0.288CS..Hα-helixtrans-58.7-41.8178.4173.40000110.6L124 I194 E520 A521 N524 R529 Q530 L531L124-V527 HydrophobicContact CD2-CG1 4.31Å; I194-V527 HydrophobicContact CD1-CG1 3.9Å; I194-V527 HydrophobicContact CD1-CG2 4.16Å; I194-V527 HydrophobicContact CG1-CG1 3.98Å; E520-V527 HydrophobicContact CG-CG2 4.33Å; A521-V527 HydrophobicContact CB-CG1 4.5Å; N524-V527 HydrophobicContact CB-CB 4.23Å; N524-V527 HydrophobicContact CB-CG2 4.24Å; N524-V527 PolarHBondContact O-N 2.89Å; N524-V527 VanDerWaalsContact O-N 3.08Å; N524-V527 PolarHBondContact OD1-N 3.33Å; V527-R529 PolarHBondContact O-N 3.3Å; V527-Q530 PolarHBondContact O-N 3.45Å; V527-L531 HydrophobicContact CG1-CD1 3.99Å; V527-L531 HydrophobicContact CG1-CG 4.44Å; V527-L531 WeakPolarHBondContact O-CG 3.48Å; V527-L531 PolarHBondContact O-N 3.37Å
528Q95.8Very high95.1Very high94 Ų9456.7 Ų56.744%0.43928%0.282SS..Hα-helixtrans-57.2-49.8175.6-161.1-175.744.400112.1A521 N524 R526 L531 L532A521-Q528 WeakPolarHBondContact O-CB 3.22Å; A521-Q528 VanDerWaalsContact O-CG 3.31Å; A521-Q528 WeakPolarHBondContact O-CG 3.42Å; N524-Q528 PolarHBondContact O-N 3.39Å; R526-Q528 VanDerWaalsContact C-N 3.27Å; R526-Q528 PolarHBondContact O-N 2.88Å; Q528-L531 PolarHBondContact O-N 2.88Å; Q528-L532 HydrophobicContact CG-CD1 4.34Å; Q528-L532 VanDerWaalsContact O-CG 3.31Å; Q528-L532 WeakPolarHBondContact O-CG 3.39Å; Q528-L532 PolarHBondContact O-N 3.36Å
529R96.3Very high95.1Very high147 Ų14757 Ų5756%0.55529%0.29SS*.Hα-helixtrans-65-37.6177.3-77.8177.9-85171.1-19.5112.9E525 R526 V527 L532 T533E525-R529 WeakPolarHBondContact O-CB 3.46Å; E525-R529 WeakPolarHBondContact O-CG 3.34Å; E525-R529 PolarHBondContact O-N 3.44Å; E525-R529 VanDerWaalsContact O-N 3.12Å; E525-R529 PolarHBondContact O-NE 2.97Å; E525-R529 IonicContact OE2-NH2 2.73Å; E525-R529 PolarHBondContact OE2-NH2 3.26Å; R526-R529 PolarHBondContact O-N 2.87Å; V527-R529 PolarHBondContact O-N 3.3Å; R529-L532 PolarHBondContact O-N 2.98Å; R529-T533 WeakPolarHBondContact O-CB 3.43Å; R529-T533 PolarHBondContact O-N 2.97Å; R529-T533 PolarHBondContact O-OG1 3.31Å
530Q95.6Very high94.8Very high7 Ų764.2 Ų64.23%0.03332%0.322CS..Hα-helixtrans-62.4-47.3176.4-70.5175.4-57.700111.2L124 W175 R526 V527 T533 L534L124-Q530 HydrophobicContact CD1-CB 4.11Å; L124-Q530 HydrophobicContact CD2-CB 4.04Å; W175-Q530 HydrophobicContact CE3-CG 4.32Å; W175-Q530 HydrophobicContact CH2-CB 4.4Å; W175-Q530 HydrophobicContact CH2-CG 4.27Å; W175-Q530 HydrophobicContact CZ3-CB 4.15Å; W175-Q530 HydrophobicContact CZ3-CG 3.67Å; R526-Q530 HydrophobicContact CG-CG 4.48Å; R526-Q530 VanDerWaalsContact O-CG 3.27Å; R526-Q530 WeakPolarHBondContact O-CG 3.36Å; R526-Q530 PolarHBondContact O-N 2.95Å; V527-Q530 PolarHBondContact O-N 3.45Å; Q530-T533 PolarHBondContact O-N 3.25Å; Q530-L534 WeakPolarHBondContact O-CB 3.23Å; Q530-L534 PolarHBondContact O-N 2.94Å
531L96.4Very high94.7Very high28 Ų2864.5 Ų64.515%0.14733%0.326CS..Hα-helixtrans-64.5-41.6177.2-68.9171.9000112.7L124 A521 V527 Q528 L534 S535L124-L531 HydrophobicContact CB-CD2 4.31Å; L124-L531 HydrophobicContact CD2-CD2 3.68Å; L124-L531 HydrophobicContact CD2-CG 3.86Å; A521-L531 HydrophobicContact CB-CD1 3.89Å; V527-L531 HydrophobicContact CG1-CD1 3.99Å; V527-L531 HydrophobicContact CG1-CG 4.44Å; V527-L531 WeakPolarHBondContact O-CG 3.48Å; V527-L531 PolarHBondContact O-N 3.37Å; Q528-L531 PolarHBondContact O-N 2.88Å; L531-L534 PolarHBondContact O-N 3.18Å; L531-S535 WeakPolarHBondContact O-CB 3.29Å; L531-S535 PolarHBondContact O-N 3.4Å
532L96Very high94.8Very high115 Ų11564.8 Ų64.860%0.60232%0.322SS*.Hα-helixtrans-63.7-42.1175.9-72.4169.7000112.4Q528 R529 S535 S536Q528-L532 HydrophobicContact CG-CD1 4.34Å; Q528-L532 VanDerWaalsContact O-CG 3.31Å; Q528-L532 WeakPolarHBondContact O-CG 3.39Å; Q528-L532 PolarHBondContact O-N 3.36Å; R529-L532 PolarHBondContact O-N 2.98Å; L532-S535 PolarHBondContact O-N 2.9Å; L532-S536 PolarHBondContact O-N 3.5Å; L532-S536 VanDerWaalsContact O-N 3.13Å
533T96.7Very high94.8Very high65 Ų6561.6 Ų61.640%0.39931%0.308SS..Hα-helixtrans-63.4-46.4176.1-54.20000110.6W175 R529 Q530 S535 S536 E537W175-T533 HydrophobicContact CH2-CG2 4.05Å; W175-T533 HydrophobicContact CZ2-CG2 3.83Å; R529-T533 WeakPolarHBondContact O-CB 3.43Å; R529-T533 PolarHBondContact O-N 2.97Å; R529-T533 PolarHBondContact O-OG1 3.31Å; Q530-T533 PolarHBondContact O-N 3.25Å; T533-S535 PolarHBondContact O-N 3.26Å; T533-S536 WeakPolarHBondContact O-CB 3.47Å; T533-S536 PolarHBondContact O-N 3.46Å; T533-E537 WeakPolarHBondContact O-CB 3.29Å; T533-E537 PolarHBondContact O-N 2.89Å
534L96.3Very high94.7Very high0 Ų062 Ų620%031%0.311CS..Hα-helixtrans-62.3-41.4176.9-85164.1000113.3E120 V123 L124 W175 Q530 L531 S536 E537 L538E120-L534 HydrophobicContact CB-CB 3.85Å; V123-L534 HydrophobicContact CB-CD1 4.38Å; V123-L534 HydrophobicContact CB-CD2 3.86Å; V123-L534 HydrophobicContact CG1-CD1 4.38Å; V123-L534 HydrophobicContact CG1-CD2 3.51Å; L124-L534 HydrophobicContact CB-CD1 3.73Å; L124-L534 HydrophobicContact CD1-CD1 4.46Å; W175-L534 HydrophobicContact CD2-CD1 4.42Å; W175-L534 HydrophobicContact CZ2-CD1 4.49Å; W175-L534 HydrophobicContact CZ2-CG 3.96Å; W175-L534 VanDerWaalsContact NE1-CD2 3.27Å; Q530-L534 WeakPolarHBondContact O-CB 3.23Å; Q530-L534 PolarHBondContact O-N 2.94Å; L531-L534 PolarHBondContact O-N 3.18Å; L534-S536 VanDerWaalsContact C-N 3.33Å; L534-S536 PolarHBondContact O-N 2.98Å; L534-E537 PolarHBondContact O-N 3.39Å; L534-L538 WeakPolarHBondContact O-CB 3.29Å; L534-L538 WeakPolarHBondContact O-CG 3.37Å; L534-L538 PolarHBondContact O-N 2.61Å
535S95.6Very high94.6Very high40 Ų4067 Ų6728%0.2834%0.338SS..Hα-helixtrans-61.9-43.2176.9-162.40000111.1E120 L531 L532 T533 S539E120-S535 VanDerWaalsContact OE1-CB 3.24Å; E120-S535 WeakPolarHBondContact OE1-CB 3.44Å; E120-S535 PolarHBondContact OE1-OG 2.88Å; L531-S535 WeakPolarHBondContact O-CB 3.29Å; L531-S535 PolarHBondContact O-N 3.4Å; L532-S535 PolarHBondContact O-N 2.9Å; T533-S535 PolarHBondContact O-N 3.26Å; S535-S539 WeakPolarHBondContact O-CB 3.27Å; S535-S539 PolarHBondContact O-N 3.31Å
536S95.3Very high94.7Very high73 Ų7365.4 Ų65.451%0.5133%0.329SS..Hα-helixtrans-61.8-50.4173.2-173.70000112.3L532 T533 L534 L538 S539L532-S536 PolarHBondContact O-N 3.5Å; L532-S536 VanDerWaalsContact O-N 3.13Å; T533-S536 WeakPolarHBondContact O-CB 3.47Å; T533-S536 PolarHBondContact O-N 3.46Å; L534-S536 VanDerWaalsContact C-N 3.33Å; L534-S536 PolarHBondContact O-N 2.98Å; S536-L538 VanDerWaalsContact C-N 3.33Å; S536-L538 PolarHBondContact O-N 3.02Å; S536-S539 PolarHBondContact O-N 3.49Å; S536-S539 PolarHBondContact O-OG 3Å
537E94Very high94.7Very high52 Ų5264.5 Ų64.524%0.24333%0.325CS..Hα-helixtrans-57.2-39.3178.9-95.8-172.8-128.400114.3R171 T533 L534R171-E537 IonicContact NH1-OE2 3.62Å; R171-E537 PolarHBondContact NH1-OE2 3.44Å; R171-E537 PolarHBondContact NH2-O 3.41Å; T533-E537 WeakPolarHBondContact O-CB 3.29Å; T533-E537 PolarHBondContact O-N 2.89Å; L534-E537 PolarHBondContact O-N 3.39Å
538L94.7Very high94.8Very high0 Ų067 Ų670%034%0.34CS..Hα-helixtrans-84.2-28-177.5-66.1176.1000112.3P119 V123 H161 L163 W168 L534 S536 Q540 A541 R542P119-L538 HydrophobicContact CB-CD1 3.86Å; V123-L538 HydrophobicContact CG2-CD1 4.07Å; H161-L538 PolarHBondContact CD2-O 3.33Å; L163-L538 HydrophobicContact CD1-CD2 4.29Å; W168-L538 HydrophobicContact CH2-CD2 3.85Å; W168-L538 HydrophobicContact CZ3-CD2 3.6Å; L534-L538 WeakPolarHBondContact O-CB 3.29Å; L534-L538 WeakPolarHBondContact O-CG 3.37Å; L534-L538 PolarHBondContact O-N 2.61Å; S536-L538 VanDerWaalsContact C-N 3.33Å; S536-L538 PolarHBondContact O-N 3.02Å; L538-Q540 PolarHBondContact O-N 3.5Å; L538-A541 PolarHBondContact O-N 3.37Å; L538-R542 PolarHBondContact O-N 2.99Å; L538-R542 VanDerWaalsContact O-N 3.15Å
539S93.4Very high94.9Very high67 Ų6767.5 Ų67.547%0.46934%0.342SS..Hα-helixtrans-53.1-38.9-18072.20000112.9S535 S536 A541 R542S535-S539 WeakPolarHBondContact O-CB 3.27Å; S535-S539 PolarHBondContact O-N 3.31Å; S536-S539 PolarHBondContact O-N 3.49Å; S536-S539 PolarHBondContact O-OG 3Å; S539-A541 PolarHBondContact O-N 2.96Å; S539-R542 PolarHBondContact O-N 3.43Å
540Q91Very high94.9Very high169 Ų16962.7 Ų62.779%0.7933%0.328SS*.THydrogen-bonded Turntrans-65.6-24.2-179-59.1-178.8700113.6L538L538-Q540 PolarHBondContact O-N 3.5Å
541A92.9Very high95Very high14 Ų1462.4 Ų62.412%0.11633%0.326CS..THydrogen-bonded Turntrans-108.4-3.4-178.100000113.4H161 K162 L163 L538 S539H161-A541 CarbonylContact C-O 3.59Å; H161-A541 VanDerWaalsContact CA-O 3.3Å; H161-A541 WeakPolarHBondContact CA-O 3.3Å; H161-A541 HydrophobicContact CB-CB 4.45Å; K162-A541 PolarHBondContact N-O 3.24Å; L163-A541 HydrophobicContact CD1-CB 4.23Å; L163-A541 HydrophobicContact CD2-CB 3.77Å; L163-A541 HydrophobicContact CG-CB 3.82Å; L538-A541 PolarHBondContact O-N 3.37Å; S539-A541 PolarHBondContact O-N 2.96Å
542R94.6Very high95Very high33 Ų3365.6 Ų65.613%0.12534%0.343CS..BIsolated β-bridgetrans-68.9140.6-174-166.1167.7-72.9-174.7-3111.5E120 H161 L538 S539E120-R542 IonicContact OE2-CZ 2.8Å; E120-R542 IonicContact OE2-NH2 3.39Å; E120-R542 PolarHBondContact OE2-NH2 2.89Å; H161-R542 PolarHBondContact NE2-NE 3.16Å; L538-R542 PolarHBondContact O-N 2.99Å; L538-R542 VanDerWaalsContact O-N 3.15Å; S539-R542 PolarHBondContact O-N 3.43Å
543D94.1Very high95.1Very high21 Ų2161.1 Ų61.111%0.11232%0.319CS..  trans-108.397.3175.3-161.22.2000110.1Q160 K162 N545 K546Q160-D543 PolarHBondContact O-N 3.45Å; K162-D543 VanDerWaalsContact CE-OD2 3.27Å; K162-D543 WeakPolarHBondContact CE-OD2 3.47Å; K162-D543 VanDerWaalsContact NZ-CG 3.29Å; K162-D543 IonicContact NZ-OD1 3.1Å; K162-D543 PolarHBondContact NZ-OD1 2.87Å; K162-D543 IonicContact NZ-OD2 2.75Å; D543-N545 PolarHBondContact O-N 3.13Å; D543-N545 PolarHBondContact OD1-ND2 2.82Å; D543-K546 HydrophobicContact CB-CB 4.48Å; D543-K546 HydrophobicContact CB-CD 4.13Å; D543-K546 HydrophobicContact CB-CG 4.21Å; D543-K546 PolarHBondContact O-N 2.86Å; D543-K546 VanDerWaalsContact OD2-CE 3.32Å; D543-K546 WeakPolarHBondContact OD2-CE 3.36Å
544E92.1Very high95.1Very high103 Ų10359.1 Ų59.148%0.48131%0.305SS..G310 helixtrans-53.7-31.3-173.9-64.9-6694.500113.6K546 R547E544-K546 PolarHBondContact O-N 3.28Å; E544-R547 VanDerWaalsContact CD-NE 3.27Å; E544-R547 WeakPolarHBondContact O-CG 3.25Å; E544-R547 IonicContact OE1-CZ 2.89Å; E544-R547 VanDerWaalsContact OE1-CZ 3.23Å; E544-R547 IonicContact OE1-NE 2.69Å; E544-R547 PolarHBondContact OE1-NE 3.37Å; E544-R547 IonicContact OE1-NH2 3.59Å; E544-R547 PolarHBondContact OE1-NH2 2.97Å; E544-R547 IonicContact OE2-CZ 2.85Å; E544-R547 IonicContact OE2-NE 2.72Å; E544-R547 PolarHBondContact OE2-NE 3.38Å; E544-R547 VanDerWaalsContact OE2-NE 3.13Å; E544-R547 IonicContact OE2-NH2 2.88Å; E544-R547 PolarHBondContact OE2-NH2 3.19Å
545N93.7Very high95.1Very high151 Ų15161.6 Ų61.681%0.80732%0.319SS*.G310 helixtrans-71.3-10179.5-53.3-74.5000114D543D543-N545 PolarHBondContact O-N 3.13Å; D543-N545 PolarHBondContact OD1-ND2 2.82Å
546K95.8Very high95.2Very high99 Ų9962.6 Ų62.643%0.4332%0.319SS..G310 helixtrans-110.14.5-176.4-61.4-172.6-175.9-174.60113.9D159 Q160 D543 E544 T548D159-K546 WeakPolarHBondContact O-CD 3.41Å; D159-K546 WeakPolarHBondContact O-CE 3.3Å; D159-K546 PolarHBondContact O-NZ 3.09Å; Q160-K546 HydrophobicContact CB-CB 3.95Å; D543-K546 HydrophobicContact CB-CB 4.48Å; D543-K546 HydrophobicContact CB-CD 4.13Å; D543-K546 HydrophobicContact CB-CG 4.21Å; D543-K546 PolarHBondContact O-N 2.86Å; D543-K546 VanDerWaalsContact OD2-CE 3.32Å; D543-K546 WeakPolarHBondContact OD2-CE 3.36Å; E544-K546 PolarHBondContact O-N 3.28Å; K546-T548 PolarHBondContact O-N 3.44Å
547R94.1Very high95.2Very high76 Ų7659.5 Ų59.529%0.28730%0.296SS..  trans-59.1125.5172.4-68.7174.4173-138.54.3109.5E544 D551 I552 N555E544-R547 VanDerWaalsContact CD-NE 3.27Å; E544-R547 WeakPolarHBondContact O-CG 3.25Å; E544-R547 IonicContact OE1-CZ 2.89Å; E544-R547 VanDerWaalsContact OE1-CZ 3.23Å; E544-R547 IonicContact OE1-NE 2.69Å; E544-R547 PolarHBondContact OE1-NE 3.37Å; E544-R547 IonicContact OE1-NH2 3.59Å; E544-R547 PolarHBondContact OE1-NH2 2.97Å; E544-R547 IonicContact OE2-CZ 2.85Å; E544-R547 IonicContact OE2-NE 2.72Å; E544-R547 PolarHBondContact OE2-NE 3.38Å; E544-R547 VanDerWaalsContact OE2-NE 3.13Å; E544-R547 IonicContact OE2-NH2 2.88Å; E544-R547 PolarHBondContact OE2-NH2 3.19Å; R547-D551 HydrophobicContact CB-CB 4.33Å; R547-I552 HydrophobicContact CB-CG1 4.34Å; R547-N555 PolarHBondContact NH1-ND2 3.44Å
548T96.8Very high95.3Very high52 Ų5262.6 Ų62.632%0.31931%0.312SS..  trans-79.8167.5173.374.50000110.9R156 K546 N550 D551 I552R156-T548 WeakPolarHBondContact CD-OG1 3.36Å; R156-T548 HydrophobicContact CG-CG2 3.78Å; K546-T548 PolarHBondContact O-N 3.44Å; T548-N550 VanDerWaalsContact C-N 3.25Å; T548-N550 PolarHBondContact O-N 3.13Å; T548-D551 WeakPolarHBondContact CA-OD2 3.21Å; T548-D551 VanDerWaalsContact CB-OD2 3.23Å; T548-D551 WeakPolarHBondContact CB-OD2 3.43Å; T548-D551 WeakPolarHBondContact CG2-OD2 3.34Å; T548-D551 PolarHBondContact N-OD2 3.49Å; T548-D551 WeakPolarHBondContact O-CB 3.35Å; T548-D551 PolarHBondContact O-N 2.95Å; T548-D551 PolarHBondContact OG1-N 2.95Å; T548-D551 PolarHBondContact OG1-OD2 3.26Å; T548-I552 WeakPolarHBondContact O-CG1 3.34Å; T548-I552 PolarHBondContact O-N 3.28Å
549H96.9Very high95.3Very high105 Ų10571.7 Ų71.749%0.48635%0.347SS..Hα-helixtrans-51.8-41.4175.5-172.367.9000113.4D231 I552 I553D231-H549 PolarHBondContact O-CD2 3.37Å; D231-H549 PolarHBondContact O-NE2 2.98Å; H549-I552 PolarHBondContact O-N 3.2Å; H549-I553 WeakPolarHBondContact NE2-CD1 3.34Å; H549-I553 WeakPolarHBondContact O-CG1 3.31Å; H549-I553 PolarHBondContact O-N 3.3Å
550N97.3Very high95.4Very high47 Ų4773.1 Ų73.125%0.25135%0.346SS..Hα-helixtrans-70.1-36.4176.6-70.20.2000112.2Y116 L234 T548 I552 I553 H554Y116-N550 HydrophobicContact CD2-CB 3.45Å; Y116-N550 VanDerWaalsContact CD2-CB 3.45Å; Y116-N550 HydrophobicContact CE2-CB 3.78Å; Y116-N550 HydrophobicContact CG-CB 4.04Å; L234-N550 HydrophobicContact CD1-CB 4.29Å; L234-N550 WeakPolarHBondContact CD1-O 3.33Å; T548-N550 VanDerWaalsContact C-N 3.25Å; T548-N550 PolarHBondContact O-N 3.13Å; N550-I552 VanDerWaalsContact C-N 3.28Å; N550-I552 PolarHBondContact O-N 2.93Å; N550-I553 PolarHBondContact O-N 3.03Å; N550-H554 WeakPolarHBondContact O-CB 3.49Å; N550-H554 PolarHBondContact O-N 3.12Å
551D96.9Very high95.6Very high0 Ų067.6 Ų67.60%033%0.334CS..Hα-helixtrans-62.8-38.7173.5-52.3-76.5000110R156 Q160 R547 T548 N555R156-D551 IonicContact CZ-OD1 3.39Å; R156-D551 IonicContact NH1-OD1 3.51Å; R156-D551 PolarHBondContact NH1-OD1 2.66Å; Q160-D551 PolarHBondContact NE2-OD1 3.2Å; Q160-D551 VanDerWaalsContact NE2-OD1 3.14Å; R547-D551 HydrophobicContact CB-CB 4.33Å; T548-D551 WeakPolarHBondContact CA-OD2 3.21Å; T548-D551 VanDerWaalsContact CB-OD2 3.23Å; T548-D551 WeakPolarHBondContact CB-OD2 3.43Å; T548-D551 WeakPolarHBondContact CG2-OD2 3.34Å; T548-D551 PolarHBondContact N-OD2 3.49Å; T548-D551 WeakPolarHBondContact O-CB 3.35Å; T548-D551 PolarHBondContact O-N 2.95Å; T548-D551 PolarHBondContact OG1-N 2.95Å; T548-D551 PolarHBondContact OG1-OD2 3.26Å; D551-N555 WeakPolarHBondContact O-CB 3.47Å; D551-N555 PolarHBondContact O-N 3.1Å; D551-N555 PolarHBondContact O-ND2 2.66Å
552I97.2Very high95.7Very high95 Ų9570.1 Ų70.149%0.48734%0.341SS..Hα-helixtrans-63.7-50176.8-64.3166.8000111.2R547 T548 H549 N550 H554 N555 E556R547-I552 HydrophobicContact CB-CG1 4.34Å; T548-I552 WeakPolarHBondContact O-CG1 3.34Å; T548-I552 PolarHBondContact O-N 3.28Å; H549-I552 PolarHBondContact O-N 3.2Å; N550-I552 VanDerWaalsContact C-N 3.28Å; N550-I552 PolarHBondContact O-N 2.93Å; I552-H554 PolarHBondContact O-N 3.34Å; I552-N555 PolarHBondContact O-N 3.22Å; I552-E556 PolarHBondContact O-N 3.33Å
553I97.8Very high95.8Very high22 Ų2270 Ų7011%0.11334%0.342CS..Hα-helixtrans-60.4-45.3178.6-67163.6000111.2D232 L234 H549 N550 E556 N557D232-I553 HydrophobicContact CB-CD1 4.09Å; L234-I553 HydrophobicContact CB-CG2 3.97Å; L234-I553 HydrophobicContact CD1-CB 4.15Å; L234-I553 HydrophobicContact CD1-CG2 4Å; L234-I553 HydrophobicContact CG-CG2 4.25Å; H549-I553 WeakPolarHBondContact NE2-CD1 3.34Å; H549-I553 WeakPolarHBondContact O-CG1 3.31Å; H549-I553 PolarHBondContact O-N 3.3Å; N550-I553 PolarHBondContact O-N 3.03Å; I553-E556 PolarHBondContact O-N 3.13Å; I553-N557 PolarHBondContact O-N 2.9Å
554H97.1Very high95.9Very high22 Ų2270 Ų7010%0.10234%0.341CS..Hα-helixtrans-62.9-45.6179.6179.979000111.9Y116 E199 L234 N550 I552 E556 N557 M558Y116-H554 HydrophobicContact CE1-CB 3.56Å; Y116-H554 AromaticContact CE1-CG 3.57Å; Y116-H554 AromaticContact CE1-ND1 3.76Å; Y116-H554 AromaticContact CZ-CG 3.95Å; Y116-H554 WeakPolarHBondContact OH-CB 3.44Å; E199-H554 IonicContact OE1-CE1 2.73Å; E199-H554 IonicContact OE1-CG 3.86Å; E199-H554 IonicContact OE1-ND1 2.82Å; E199-H554 PolarHBondContact OE1-ND1 3.34Å; E199-H554 IonicContact OE2-ND1 3.22Å; L234-H554 HydrophobicContact CD1-CB 3.88Å; N550-H554 WeakPolarHBondContact O-CB 3.49Å; N550-H554 PolarHBondContact O-N 3.12Å; I552-H554 PolarHBondContact O-N 3.34Å; H554-E556 VanDerWaalsContact C-N 3.25Å; H554-E556 PolarHBondContact O-N 3.31Å; H554-N557 PolarHBondContact O-N 3.35Å; H554-M558 WeakPolarHBondContact O-CG 3.43Å; H554-M558 PolarHBondContact O-N 3.48Å
555N95.8Very high96Very high53 Ų5365.4 Ų65.428%0.28332%0.32SS..Hα-helixtrans-59.2-36.9175.1-80.9-70.5000111.9R547 D551 I552 R559R547-N555 PolarHBondContact NH1-ND2 3.44Å; D551-N555 WeakPolarHBondContact O-CB 3.47Å; D551-N555 PolarHBondContact O-N 3.1Å; D551-N555 PolarHBondContact O-ND2 2.66Å; I552-N555 PolarHBondContact O-N 3.22Å; N555-R559 WeakPolarHBondContact O-CB 3.5Å; N555-R559 PolarHBondContact O-N 3.09Å
556E97.1Very high96.1Very high60 Ų6061.7 Ų61.728%0.2830%0.296SS..Hα-helixtrans-70-42.1176.5-17556.6-155.900112.6I552 I553 H554 R559 Q560I552-E556 PolarHBondContact O-N 3.33Å; I553-E556 PolarHBondContact O-N 3.13Å; H554-E556 VanDerWaalsContact C-N 3.25Å; H554-E556 PolarHBondContact O-N 3.31Å; E556-R559 WeakPolarHBondContact O-CB 3.37Å; E556-R559 PolarHBondContact O-N 3.3Å; E556-R559 IonicContact OE1-CZ 3.1Å; E556-R559 IonicContact OE1-NE 2.67Å; E556-R559 PolarHBondContact OE1-NE 3.24Å; E556-R559 IonicContact OE1-NH2 2.6Å; E556-R559 PolarHBondContact OE1-NH2 3.28Å; E556-R559 IonicContact OE2-CZ 2.77Å; E556-R559 IonicContact OE2-NE 2.81Å; E556-R559 PolarHBondContact OE2-NE 3.33Å; E556-R559 IonicContact OE2-NH2 2.69Å; E556-R559 PolarHBondContact OE2-NH2 3.37Å; E556-Q560 WeakPolarHBondContact O-CG 3.42Å; E556-Q560 PolarHBondContact O-N 2.89Å; E556-Q560 PolarHBondContact OE1-NE2 3.42Å
557N96.8Very high96.2Very high8 Ų857.4 Ų57.44%0.04328%0.279CS..Hα-helixtrans-61-45.3174.3-79.7-29.7000111.4T235 I553 H554 R559 Q560 G561 R562T235-N557 PolarHBondContact OG1-ND2 3.33Å; I553-N557 PolarHBondContact O-N 2.9Å; H554-N557 PolarHBondContact O-N 3.35Å; N557-R559 PolarHBondContact O-N 3.16Å; N557-Q560 CarbonylContact O-C 3.59Å; N557-Q560 PolarHBondContact O-N 3.26Å; N557-Q560 VanDerWaalsContact O-N 3.15Å; N557-G561 PolarHBondContact O-N 3.3Å; N557-R562 HydrophobicContact CB-CB 4.12Å; N557-R562 WeakPolarHBondContact O-CB 3.38Å; N557-R562 PolarHBondContact O-N 3.18Å; N557-R562 VanDerWaalsContact OD1-CD 3.24Å; N557-R562 WeakPolarHBondContact OD1-CD 3.48Å; N557-R562 PolarHBondContact OD1-NH1 2.68Å
558M94.6Very high96.2Very high117 Ų11754.4 Ų54.458%0.57627%0.268SS*.Hα-helixtrans-61.1-41.9174.5-70.1-63.8-69.100111.9H554 Q560 G561H554-M558 WeakPolarHBondContact O-CG 3.43Å; H554-M558 PolarHBondContact O-N 3.48Å; M558-Q560 VanDerWaalsContact C-N 3.26Å; M558-Q560 PolarHBondContact O-N 3.44Å; M558-G561 PolarHBondContact O-N 3.13Å
559R95.8Very high96.1Very high191 Ų19155.5 Ų55.572%0.72127%0.267SS*.Hα-helixtrans-61.4-32.7174.7-172.317675.2143.55.6112.8N555 E556 N557 G561N555-R559 WeakPolarHBondContact O-CB 3.5Å; N555-R559 PolarHBondContact O-N 3.09Å; E556-R559 WeakPolarHBondContact O-CB 3.37Å; E556-R559 PolarHBondContact O-N 3.3Å; E556-R559 IonicContact OE1-CZ 3.1Å; E556-R559 IonicContact OE1-NE 2.67Å; E556-R559 PolarHBondContact OE1-NE 3.24Å; E556-R559 IonicContact OE1-NH2 2.6Å; E556-R559 PolarHBondContact OE1-NH2 3.28Å; E556-R559 IonicContact OE2-CZ 2.77Å; E556-R559 IonicContact OE2-NE 2.81Å; E556-R559 PolarHBondContact OE2-NE 3.33Å; E556-R559 IonicContact OE2-NH2 2.69Å; E556-R559 PolarHBondContact OE2-NH2 3.37Å; N557-R559 PolarHBondContact O-N 3.16Å; R559-G561 VanDerWaalsContact C-N 3.3Å
560Q95.8Very high96.1Very high98 Ų9855.5 Ų55.546%0.45827%0.267SS..THydrogen-bonded Turntrans-85.95.2175.4-65.7-176.325.300113.6E556 N557 M558 R562E556-Q560 WeakPolarHBondContact O-CG 3.42Å; E556-Q560 PolarHBondContact O-N 2.89Å; E556-Q560 PolarHBondContact OE1-NE2 3.42Å; N557-Q560 CarbonylContact O-C 3.59Å; N557-Q560 PolarHBondContact O-N 3.26Å; N557-Q560 VanDerWaalsContact O-N 3.15Å; M558-Q560 VanDerWaalsContact C-N 3.26Å; M558-Q560 PolarHBondContact O-N 3.44Å; Q560-R562 VanDerWaalsContact C-N 3.25Å; Q560-R562 HydrophobicContact CB-CG 4.27Å; Q560-R562 PolarHBondContact O-N 3.46Å
561G94.6Very high96Very high52 Ų5254 Ų5454%0.53626%0.258SS..THydrogen-bonded Turntrans68.221.5-179.100000114.3N557 M558 R559N557-G561 PolarHBondContact O-N 3.3Å; M558-G561 PolarHBondContact O-N 3.13Å; R559-G561 VanDerWaalsContact C-N 3.3Å
562R95.8Very high95.9Very high68 Ų6854.7 Ų54.726%0.25726%0.261SS..  trans-85.7146.6177.6-66.7176.8177.91583.4111.4N557 Q560N557-R562 HydrophobicContact CB-CB 4.12Å; N557-R562 WeakPolarHBondContact O-CB 3.38Å; N557-R562 PolarHBondContact O-N 3.18Å; N557-R562 VanDerWaalsContact OD1-CD 3.24Å; N557-R562 WeakPolarHBondContact OD1-CD 3.48Å; N557-R562 PolarHBondContact OD1-NH1 2.68Å; Q560-R562 VanDerWaalsContact C-N 3.25Å; Q560-R562 HydrophobicContact CB-CG 4.27Å; Q560-R562 PolarHBondContact O-N 3.46Å
563D95.5Very high95.7Very high29 Ų2956.5 Ų56.516%0.15527%0.268CS..  trans-135.7179.3162.565.161.3000109.4T519 Y565 K566 T567T519-D563 HydrophobicContact CG2-CB 4.06Å; D563-Y565 PolarHBondContact O-N 2.73Å; D563-Y565 WeakPolarHBondContact OD1-CA 3.39Å; D563-Y565 PolarHBondContact OD1-N 3.18Å; D563-K566 PolarHBondContact O-N 3.42Å; D563-K566 PolarHBondContact OD1-N 3.26Å; D563-K566 WeakPolarHBondContact OD2-CD 3.4Å; D563-K566 WeakPolarHBondContact OD2-CE 3.37Å; D563-K566 WeakPolarHBondContact OD2-CG 3.49Å; D563-K566 IonicContact OD2-NZ 3.19Å; D563-K566 PolarHBondContact OD2-NZ 2.69Å; D563-T567 VanDerWaalsContact O-CB 3.27Å; D563-T567 WeakPolarHBondContact O-CB 3.33Å; D563-T567 PolarHBondContact O-N 3.31Å; D563-T567 PolarHBondContact O-OG1 3.48Å
564K96.1Very high95.4Very high22 Ų2257.3 Ų57.310%0.09628%0.281CS..Hα-helixtrans-52.3-47.8179.3-173169.9-171.5167.20113.2Q196 D197 L198 Y201 L568Q196-K564 PolarHBondContact O-NZ 3.25Å; D197-K564 WeakPolarHBondContact O-CB 3.21Å; D197-K564 WeakPolarHBondContact O-CD 3.36Å; L198-K564 PolarHBondContact O-NZ 3.28Å; Y201-K564 PolarHBondContact O-NZ 2.8Å; Y201-K564 VanDerWaalsContact O-NZ 3.07Å; K564-L568 HydrophobicContact CG-CD1 4.17Å; K564-L568 WeakPolarHBondContact O-CB 3.49Å; K564-L568 WeakPolarHBondContact O-CG 3.41Å; K564-L568 PolarHBondContact O-N 3.24Å
565Y95.5Very high95.2Very high6 Ų660.7 Ų60.72%0.02430%0.3CS..Hα-helixtrans-82-35.4-175.7-54.3-63.6000112.9D197 L223 R517 T519 D563 T567 L568 R569D197-Y565 VanDerWaalsContact OD1-CE2 3.26Å; D197-Y565 WeakPolarHBondContact OD1-CE2 3.28Å; D197-Y565 PolarHBondContact OD1-OH 2.82Å; D197-Y565 VanDerWaalsContact OD1-OH 3.05Å; L223-Y565 HydrophobicContact CD1-CE1 4.47Å; R517-Y565 HydrophobicContact CB-CD1 3.74Å; R517-Y565 HydrophobicContact CB-CD2 4.23Å; R517-Y565 HydrophobicContact CB-CE1 3.97Å; R517-Y565 HydrophobicContact CB-CE2 4.41Å; R517-Y565 HydrophobicContact CB-CG 3.89Å; R517-Y565 VanDerWaalsContact CZ-OH 3.32Å; R517-Y565 PolarHBondContact NH2-OH 3.4Å; R517-Y565 VanDerWaalsContact O-CB 3.24Å; R517-Y565 WeakPolarHBondContact O-CB 3.37Å; T519-Y565 HydrophobicContact CG2-CD2 3.93Å; T519-Y565 HydrophobicContact CG2-CE2 4.07Å; D563-Y565 PolarHBondContact O-N 2.73Å; D563-Y565 WeakPolarHBondContact OD1-CA 3.39Å; D563-Y565 PolarHBondContact OD1-N 3.18Å; Y565-T567 VanDerWaalsContact C-N 3.32Å; Y565-L568 HydrophobicContact CD1-CD1 4.37Å; Y565-L568 PolarHBondContact O-N 3.2Å; Y565-R569 WeakPolarHBondContact O-CB 3.4Å; Y565-R569 WeakPolarHBondContact O-CG 3.32Å; Y565-R569 PolarHBondContact O-N 3.18Å
566K95.6Very high95.2Very high73 Ų7358.8 Ų58.832%0.31729%0.291SS..Hα-helixtrans-61.5-41.8170.7-70.8-178.8-175.684.90110.6E522 D563 Q570E522-K566 VanDerWaalsContact CD-NZ 3.29Å; E522-K566 IonicContact OE1-NZ 2.64Å; E522-K566 PolarHBondContact OE1-NZ 3.15Å; E522-K566 VanDerWaalsContact OE1-NZ 3.16Å; E522-K566 IonicContact OE2-NZ 3.97Å; E522-K566 PolarHBondContact OE2-NZ 2.69Å; D563-K566 PolarHBondContact O-N 3.42Å; D563-K566 PolarHBondContact OD1-N 3.26Å; D563-K566 WeakPolarHBondContact OD2-CD 3.4Å; D563-K566 WeakPolarHBondContact OD2-CE 3.37Å; D563-K566 WeakPolarHBondContact OD2-CG 3.49Å; D563-K566 IonicContact OD2-NZ 3.19Å; D563-K566 PolarHBondContact OD2-NZ 2.69Å; K566-Q570 PolarHBondContact O-N 3.25Å; K566-Q570 VanDerWaalsContact O-N 3.08Å
567T96.3Very high95.1Very high10 Ų1060.7 Ų60.76%0.06130%0.298CS..Hα-helixtrans-68.5-46.3175.6-50.50000111.6T235 P236 D563 Y565 R569 Q570 I571T235-T567 HydrophobicContact CG2-CG2 4.13Å; P236-T567 HydrophobicContact CG-CG2 4.11Å; D563-T567 VanDerWaalsContact O-CB 3.27Å; D563-T567 WeakPolarHBondContact O-CB 3.33Å; D563-T567 PolarHBondContact O-N 3.31Å; D563-T567 PolarHBondContact O-OG1 3.48Å; Y565-T567 VanDerWaalsContact C-N 3.32Å; T567-R569 VanDerWaalsContact C-N 3.31Å; T567-R569 PolarHBondContact O-N 3.23Å; T567-Q570 WeakPolarHBondContact O-CB 3.46Å; T567-Q570 PolarHBondContact O-N 3.28Å; T567-I571 HydrophobicContact CG2-CG2 4.3Å; T567-I571 WeakPolarHBondContact O-CG2 3.39Å; T567-I571 PolarHBondContact O-N 2.81Å
568L95.3Very high95.1Very high13 Ų1364.2 Ų64.27%0.06831%0.314CS..Hα-helixtrans-59.1-38.6175.7-77.1170.2000112.7L223 K564 Y565 I571 R572L223-L568 HydrophobicContact CD1-CD1 3.79Å; K564-L568 HydrophobicContact CG-CD1 4.17Å; K564-L568 WeakPolarHBondContact O-CB 3.49Å; K564-L568 WeakPolarHBondContact O-CG 3.41Å; K564-L568 PolarHBondContact O-N 3.24Å; Y565-L568 HydrophobicContact CD1-CD1 4.37Å; Y565-L568 PolarHBondContact O-N 3.2Å; L568-I571 HydrophobicContact CD2-CD1 4.11Å; L568-R572 WeakPolarHBondContact O-CB 3.49Å; L568-R572 VanDerWaalsContact O-CD 3.23Å; L568-R572 WeakPolarHBondContact O-CD 3.48Å; L568-R572 WeakPolarHBondContact O-CG 3.3Å
569R94.9Very high95.3Very high75 Ų7558.9 Ų58.928%0.28329%0.287SS..Hα-helixtrans-60.4-47.7170.6-83-177.3-78.2-850.9111.6E515 R517 Y565 T567 R572E515-R569 VanDerWaalsContact O-CD 3.24Å; E515-R569 WeakPolarHBondContact O-CD 3.45Å; E515-R569 WeakPolarHBondContact O-CG 3.36Å; E515-R569 PolarHBondContact O-NH1 3.36Å; R517-R569 PolarHBondContact O-NH1 2.86Å; R517-R569 PolarHBondContact O-NH2 3.1Å; Y565-R569 WeakPolarHBondContact O-CB 3.4Å; Y565-R569 WeakPolarHBondContact O-CG 3.32Å; Y565-R569 PolarHBondContact O-N 3.18Å; T567-R569 VanDerWaalsContact C-N 3.31Å; T567-R569 PolarHBondContact O-N 3.23Å; R569-R572 PolarHBondContact O-N 3.28Å
570Q95.4Very high95.3Very high104 Ų10449.9 Ų49.949%0.48625%0.254SS..Hα-helixtrans-61.9-50.2-176.6-173.9176.21.600112.1K566 T567 R572 Q573K566-Q570 PolarHBondContact O-N 3.25Å; K566-Q570 VanDerWaalsContact O-N 3.08Å; T567-Q570 WeakPolarHBondContact O-CB 3.46Å; T567-Q570 PolarHBondContact O-N 3.28Å; Q570-R572 PolarHBondContact O-N 3.34Å; Q570-R572 VanDerWaalsContact O-N 3.16Å; Q570-Q573 WeakPolarHBondContact O-CB 3.5Å; Q570-Q573 WeakPolarHBondContact O-CG 3.45Å; Q570-Q573 PolarHBondContact O-N 3.4Å
571I95.5Very high95.3Very high16 Ų1649.1 Ų49.18%0.08225%0.253CS..THydrogen-bonded Turntrans-72.9-5.8-175.871.5176.1000114.6P236 K237 G239 T567 L568 R579P236-I571 HydrophobicContact CB-CD1 3.65Å; P236-I571 HydrophobicContact CG-CD1 3.66Å; P236-I571 WeakPolarHBondContact O-CG2 3.35Å; K237-I571 WeakPolarHBondContact O-CG2 3.36Å; G239-I571 PolarHBondContact N-O 3.43Å; T567-I571 HydrophobicContact CG2-CG2 4.3Å; T567-I571 WeakPolarHBondContact O-CG2 3.39Å; T567-I571 PolarHBondContact O-N 2.81Å; L568-I571 HydrophobicContact CD2-CD1 4.11Å; I571-R579 VanDerWaalsContact O-CD 3.23Å; I571-R579 WeakPolarHBondContact O-CD 3.45Å
572R95.5Very high95.4Very high15 Ų1550.3 Ų50.36%0.05724%0.244CC..THydrogen-bonded Turntrans-102.6-1.8177.5-69.4174.1-175.7-155.7-8.7112.4L223 L568 R569 Q570 R579L223-R572 PolarHBondContact O-NH1 3.06Å; L223-R572 PolarHBondContact O-NH2 3.19Å; L568-R572 WeakPolarHBondContact O-CB 3.49Å; L568-R572 VanDerWaalsContact O-CD 3.23Å; L568-R572 WeakPolarHBondContact O-CD 3.48Å; L568-R572 WeakPolarHBondContact O-CG 3.3Å; R569-R572 PolarHBondContact O-N 3.28Å; Q570-R572 PolarHBondContact O-N 3.34Å; Q570-R572 VanDerWaalsContact O-N 3.16Å; R572-R579 PolarHBondContact O-NE 2.97Å; R572-R579 PolarHBondContact O-NH2 2.63Å
573Q92.5Very high95.5Very high133 Ų13347 Ų4762%0.62123%0.232SC*.  trans-64.2162.7173.1-65.5-177.94.800111.4Q570 R579Q570-Q573 WeakPolarHBondContact O-CB 3.5Å; Q570-Q573 WeakPolarHBondContact O-CG 3.45Å; Q570-Q573 PolarHBondContact O-N 3.4Å; Q573-R579 VanDerWaalsContact O-CD 3.24Å; Q573-R579 WeakPolarHBondContact O-CD 3.4Å; Q573-R579 PolarHBondContact O-NE 3.36Å
574G92.3Very high95.5Very high39 Ų3947.2 Ų47.240%0.40223%0.232SC..SBendtrans71.6169.9-172.900000113.3R579G574-R579 PolarHBondContact O-NE 2.82Å; G574-R579 PolarHBondContact O-NH2 2.89Å
575N93.6Very high95.4Very high92 Ų9249.5 Ų49.549%0.49226%0.255SS..  trans-79.8161.2177.36271.4000111.4K577 Q578 R579N575-K577 PolarHBondContact O-N 2.91Å; N575-K577 VanDerWaalsContact O-N 3.16Å; N575-K577 WeakPolarHBondContact OD1-CB 3.45Å; N575-K577 PolarHBondContact OD1-N 3.28Å; N575-Q578 WeakPolarHBondContact O-CB 3.21Å; N575-Q578 PolarHBondContact O-N 3.01Å; N575-Q578 PolarHBondContact OD1-N 3.3Å; N575-R579 PolarHBondContact O-N 2.96Å
576T94.6Very high95.3Very high14 Ų1452 Ų529%0.08627%0.269CS..Hα-helixtrans-59-30.3-177.1-44.40000113.2F240 E244 P259 A264 I580F240-T576 HydrophobicContact CD1-CG2 4Å; F240-T576 HydrophobicContact CE1-CG2 4Å; E244-T576 PolarHBondContact OE2-OG1 2.94Å; P259-T576 HydrophobicContact CB-CG2 3.86Å; A264-T576 HydrophobicContact CB-CG2 4.44Å; T576-I580 HydrophobicContact CG2-CD1 4.2Å; T576-I580 WeakPolarHBondContact O-CD1 3.06Å; T576-I580 VanDerWaalsContact O-CG1 3.26Å; T576-I580 WeakPolarHBondContact O-CG1 3.32Å; T576-I580 PolarHBondContact O-N 3Å
577K95.9Very high95.3Very high100 Ų10051 Ų5144%0.43527%0.266SS..Hα-helixtrans-64.5-50.9172.9172.9179.6169.2-175.30111.1A264 P265 N575 R579 I580 D581A264-K577 HydrophobicContact CB-CB 4.19Å; P265-K577 HydrophobicContact CG-CG 4.39Å; N575-K577 PolarHBondContact O-N 2.91Å; N575-K577 VanDerWaalsContact O-N 3.16Å; N575-K577 WeakPolarHBondContact OD1-CB 3.45Å; N575-K577 PolarHBondContact OD1-N 3.28Å; K577-R579 VanDerWaalsContact C-N 3.28Å; K577-R579 PolarHBondContact O-N 3.38Å; K577-I580 WeakPolarHBondContact O-CA 3.21Å; K577-I580 PolarHBondContact O-N 3.45Å; K577-D581 WeakPolarHBondContact CE-OD2 3.46Å; K577-D581 WeakPolarHBondContact CG-OD2 3.18Å; K577-D581 IonicContact NZ-OD2 3.52Å; K577-D581 PolarHBondContact O-N 3.42Å
578Q96.6Very high95.2Very high82 Ų8253.2 Ų53.238%0.38328%0.277SS..Hα-helixtrans-53-47.9179.8-178.8-169.1-27.400111N575 I580 D581 E582N575-Q578 WeakPolarHBondContact O-CB 3.21Å; N575-Q578 PolarHBondContact O-N 3.01Å; N575-Q578 PolarHBondContact OD1-N 3.3Å; Q578-I580 VanDerWaalsContact C-N 3.27Å; Q578-I580 PolarHBondContact O-N 3.19Å; Q578-D581 PolarHBondContact O-N 3.07Å; Q578-D581 VanDerWaalsContact O-N 3.16Å; Q578-E582 WeakPolarHBondContact CG-OE1 3.48Å; Q578-E582 PolarHBondContact NE2-OE1 3.43Å; Q578-E582 WeakPolarHBondContact O-CB 3.18Å; Q578-E582 VanDerWaalsContact O-CG 3.31Å; Q578-E582 WeakPolarHBondContact O-CG 3.3Å; Q578-E582 PolarHBondContact O-N 3.37Å
579R97.3Very high95.2Very high4 Ų455.4 Ų55.42%0.01529%0.288CS..Hα-helixtrans-65-25178.3-76.7-178.2-89.1121.7-2114I238 G239 F240 E244 I571 R572 Q573 G574 N575 K577 F583I238-R579 HydrophobicContact CG2-CB 3.82Å; I238-R579 HydrophobicContact CG2-CG 4.19Å; I238-R579 WeakPolarHBondContact CG2-O 3.36Å; G239-R579 WeakPolarHBondContact O-CD 3.37Å; G239-R579 PolarHBondContact O-NH1 3.45Å; F240-R579 HydrophobicContact CE1-CB 3.66Å; F240-R579 HydrophobicContact CZ-CB 3.88Å; E244-R579 IonicContact OE1-CZ 4Å; E244-R579 IonicContact OE1-NH1 2.71Å; E244-R579 IonicContact OE1-NH2 3.29Å; E244-R579 PolarHBondContact OE1-NH2 3.09Å; E244-R579 IonicContact OE2-CZ 2.91Å; E244-R579 IonicContact OE2-NH1 2.71Å; E244-R579 PolarHBondContact OE2-NH1 2.78Å; E244-R579 IonicContact OE2-NH2 3.18Å; E244-R579 PolarHBondContact OE2-NH2 2.7Å; E244-R579 VanDerWaalsContact OE2-NH2 3.12Å; I571-R579 VanDerWaalsContact O-CD 3.23Å; I571-R579 WeakPolarHBondContact O-CD 3.45Å; R572-R579 PolarHBondContact O-NE 2.97Å; R572-R579 PolarHBondContact O-NH2 2.63Å; Q573-R579 VanDerWaalsContact O-CD 3.24Å; Q573-R579 WeakPolarHBondContact O-CD 3.4Å; Q573-R579 PolarHBondContact O-NE 3.36Å; G574-R579 PolarHBondContact O-NE 2.82Å; G574-R579 PolarHBondContact O-NH2 2.89Å; N575-R579 PolarHBondContact O-N 2.96Å; K577-R579 VanDerWaalsContact C-N 3.28Å; K577-R579 PolarHBondContact O-N 3.38Å; R579-F583 PolarHBondContact O-N 3.07Å
580I96.9Very high95.2Very high3 Ų354.2 Ų54.22%0.01529%0.289CS..Hα-helixtrans-80.4-40.1171.9-65.5165.6000111.2F240 P265 F267 T576 K577 Q578 E582 F583 E584F240-I580 HydrophobicContact CE1-CG1 3.88Å; F240-I580 HydrophobicContact CZ-CG1 3.8Å; P265-I580 HydrophobicContact CG-CB 4.23Å; P265-I580 HydrophobicContact CG-CD1 4.15Å; P265-I580 HydrophobicContact CG-CG2 3.9Å; P265-I580 VanDerWaalsContact O-CD1 3.24Å; P265-I580 WeakPolarHBondContact O-CD1 3.18Å; F267-I580 HydrophobicContact CB-CD1 3.81Å; F267-I580 HydrophobicContact CB-CG1 3.98Å; F267-I580 HydrophobicContact CD2-CG1 4.22Å; F267-I580 HydrophobicContact CG-CG1 4.41Å; T576-I580 HydrophobicContact CG2-CD1 4.2Å; T576-I580 WeakPolarHBondContact O-CD1 3.06Å; T576-I580 VanDerWaalsContact O-CG1 3.26Å; T576-I580 WeakPolarHBondContact O-CG1 3.32Å; T576-I580 PolarHBondContact O-N 3Å; K577-I580 WeakPolarHBondContact O-CA 3.21Å; K577-I580 PolarHBondContact O-N 3.45Å; Q578-I580 VanDerWaalsContact C-N 3.27Å; Q578-I580 PolarHBondContact O-N 3.19Å; I580-E582 VanDerWaalsContact C-N 3.3Å; I580-E582 PolarHBondContact O-N 3.33Å; I580-F583 WeakPolarHBondContact O-CB 3.43Å; I580-F583 PolarHBondContact O-N 2.96Å; I580-E584 PolarHBondContact O-N 2.91Å; I580-E584 VanDerWaalsContact O-N 3.11Å
581D95.4Very high95.2Very high82 Ų8251.1 Ų51.144%0.43928%0.276SS..Hα-helixtrans-63.7-37.7175.3-66.9-21.7000110.6K577 Q578 E584 A585K577-D581 WeakPolarHBondContact CE-OD2 3.46Å; K577-D581 WeakPolarHBondContact CG-OD2 3.18Å; K577-D581 IonicContact NZ-OD2 3.52Å; K577-D581 PolarHBondContact O-N 3.42Å; Q578-D581 PolarHBondContact O-N 3.07Å; Q578-D581 VanDerWaalsContact O-N 3.16Å; D581-E584 CarbonylContact O-C 3.51Å; D581-E584 PolarHBondContact O-N 2.72Å; D581-A585 WeakPolarHBondContact O-CB 3.01Å; D581-A585 PolarHBondContact O-N 2.66Å
582E96.7Very high95.2Very high76 Ų7653.5 Ų53.536%0.35529%0.289SS..Hα-helixtrans-63.2-40.5171-74.1164.9179.700112.5I238 Q578 I580 E584 A585 L586I238-E582 HydrophobicContact CD1-CB 3.89Å; Q578-E582 WeakPolarHBondContact CG-OE1 3.48Å; Q578-E582 PolarHBondContact NE2-OE1 3.43Å; Q578-E582 WeakPolarHBondContact O-CB 3.18Å; Q578-E582 VanDerWaalsContact O-CG 3.31Å; Q578-E582 WeakPolarHBondContact O-CG 3.3Å; Q578-E582 PolarHBondContact O-N 3.37Å; I580-E582 VanDerWaalsContact C-N 3.3Å; I580-E582 PolarHBondContact O-N 3.33Å; E582-E584 VanDerWaalsContact C-N 3.33Å; E582-E584 PolarHBondContact O-N 2.57Å; E582-A585 WeakPolarHBondContact O-CA 3.25Å; E582-A585 VanDerWaalsContact O-CB 3.27Å; E582-A585 WeakPolarHBondContact O-CB 3.47Å; E582-A585 PolarHBondContact O-N 2.84Å; E582-L586 PolarHBondContact O-N 2.83Å
583F97.5Very high95.2Very high0 Ų056.2 Ų56.20%031%0.306CS..Hα-helixtrans-64.5-36.1176.8168.1-95000113I208 N210 L216 I227 I238 F267 V268 F269 R579 I580 A585I208-F583 HydrophobicContact CD1-CE2 4.02Å; I208-F583 HydrophobicContact CD1-CZ 4.21Å; N210-F583 HydrophobicContact CB-CD1 4.03Å; N210-F583 HydrophobicContact CB-CE1 3.36Å; N210-F583 HydrophobicContact CB-CE2 4.21Å; N210-F583 HydrophobicContact CB-CZ 3.47Å; N210-F583 VanDerWaalsContact CB-CZ 3.47Å; N210-F583 PolarHBondContact ND2-O 3.36Å; L216-F583 HydrophobicContact CD1-CD2 4.05Å; L216-F583 HydrophobicContact CD1-CE2 3.58Å; L216-F583 HydrophobicContact CD1-CZ 4.29Å; I227-F583 HydrophobicContact CD1-CD2 4.38Å; I227-F583 HydrophobicContact CD1-CE2 4.22Å; I227-F583 HydrophobicContact CG1-CD2 4.02Å; I227-F583 HydrophobicContact CG1-CE2 4.33Å; I227-F583 HydrophobicContact CG2-CD2 3.94Å; I227-F583 HydrophobicContact CG2-CE2 4.02Å; I238-F583 VanDerWaalsContact CD1-CA 3.43Å; I238-F583 HydrophobicContact CD1-CB 3.77Å; I238-F583 VanDerWaalsContact CD1-N 3.31Å; F267-F583 HydrophobicContact CD2-CD1 4.13Å; F267-F583 HydrophobicContact CD2-CE1 4.38Å; F267-F583 HydrophobicContact CD2-CG 4.43Å; F267-F583 HydrophobicContact CE2-CB 4.37Å; F267-F583 AromaticContact CE2-CD1 3.57Å; F267-F583 HydrophobicContact CE2-CD1 3.57Å; F267-F583 AromaticContact CE2-CD2 3.84Å; F267-F583 HydrophobicContact CE2-CD2 3.84Å; F267-F583 AromaticContact CE2-CE1 3.66Å; F267-F583 HydrophobicContact CE2-CE1 3.66Å; F267-F583 AromaticContact CE2-CE2 3.93Å; F267-F583 HydrophobicContact CE2-CE2 3.93Å; F267-F583 AromaticContact CE2-CG 3.65Å; F267-F583 HydrophobicContact CE2-CG 3.65Å; F267-F583 AromaticContact CE2-CZ 3.85Å; F267-F583 HydrophobicContact CE2-CZ 3.85Å; F267-F583 HydrophobicContact CZ-CD2 4.34Å; F267-F583 HydrophobicContact CZ-CE2 4.2Å; F267-F583 HydrophobicContact CZ-CZ 4.3Å; V268-F583 WeakPolarHBondContact O-CE1 3.35Å; F269-F583 HydrophobicContact CB-CE1 4.46Å; F269-F583 HydrophobicContact CB-CZ 3.9Å; R579-F583 PolarHBondContact O-N 3.07Å; I580-F583 WeakPolarHBondContact O-CB 3.43Å; I580-F583 PolarHBondContact O-N 2.96Å; F583-A585 VanDerWaalsContact C-N 3.27Å
584E95.8Very high95.4Very high33 Ų3350.3 Ų50.315%0.15428%0.282CS..THydrogen-bonded Turntrans-82.2-5.4172.2-55.9-64.9178.200112.3K211 K212 I580 D581 E582K211-E584 VanDerWaalsContact CB-OE2 3.23Å; K211-E584 WeakPolarHBondContact CB-OE2 3.46Å; K211-E584 WeakPolarHBondContact CG-OE1 3.4Å; K211-E584 WeakPolarHBondContact CG-OE2 3.32Å; K211-E584 PolarHBondContact N-OE2 2.75Å; K211-E584 IonicContact NZ-OE1 3.47Å; K211-E584 PolarHBondContact NZ-OE1 3.36Å; K212-E584 WeakPolarHBondContact CD-O 3.28Å; K212-E584 WeakPolarHBondContact CE-O 2.96Å; K212-E584 PolarHBondContact NZ-O 2.83Å; I580-E584 PolarHBondContact O-N 2.91Å; I580-E584 VanDerWaalsContact O-N 3.11Å; D581-E584 CarbonylContact O-C 3.51Å; D581-E584 PolarHBondContact O-N 2.72Å; E582-E584 VanDerWaalsContact C-N 3.33Å; E582-E584 PolarHBondContact O-N 2.57Å
585A95.3Very high95.7Very high70 Ų7051.3 Ų51.358%0.57927%0.272SS*.THydrogen-bonded Turntrans-84.4-29.1173.200000112.7K212 D581 E582 F583K212-A585 PolarHBondContact NZ-O 3.34Å; D581-A585 WeakPolarHBondContact O-CB 3.01Å; D581-A585 PolarHBondContact O-N 2.66Å; E582-A585 WeakPolarHBondContact O-CA 3.25Å; E582-A585 VanDerWaalsContact O-CB 3.27Å; E582-A585 WeakPolarHBondContact O-CB 3.47Å; E582-A585 PolarHBondContact O-N 2.84Å; F583-A585 VanDerWaalsContact C-N 3.27Å
586L92.5Very high95.9Very high59 Ų5947.5 Ų47.531%0.30925%0.252SS..  trans-56.70165.1-56.5174.6000112.2N210 K212 T214 L216 I238 E582N210-L586 PolarHBondContact ND2-OXT 2.73Å; K212-L586 WeakPolarHBondContact CD-OXT 3.39Å; K212-L586 PolarHBondContact NZ-OXT 2.83Å; T214-L586 WeakPolarHBondContact CB-O 3.36Å; T214-L586 WeakPolarHBondContact CG2-O 3.49Å; T214-L586 VanDerWaalsContact OG1-C 3.32Å; T214-L586 PolarHBondContact OG1-O 2.75Å; T214-L586 PolarHBondContact OG1-OXT 2.67Å; L216-L586 HydrophobicContact CD1-CB 4.37Å; L216-L586 HydrophobicContact CD1-CD1 4Å; L216-L586 HydrophobicContact CD2-CB 4.47Å; L216-L586 HydrophobicContact CD2-CD1 3.98Å; I238-L586 HydrophobicContact CD1-CD1 4.08Å; E582-L586 PolarHBondContact O-N 2.83Å

Retrieved 586 of 586 residues in 886 ms (Link to these results)