A0A2K6EDA5_MACNE Loading...

Eukaryotic translation initiation factor 3 subunit E

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.

AlphaFold DB , UniProt , Accession A0A2K6EDA5, Species MACNE (Macaca nemestrina, Pig-tailed macaque), Gene EIF3E, Length 496 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	27.5	Very low	23.6	Very low	228 Å²	228	163.5 Å²	163.5	100%	1.123	82%	0.819	S	S	*	*				0	109.2	0	-83.5	177.4	174.8	0	0	107.3
2	R	22.2	Very low	23.9	Very low	202 Å²	202	160 Å²	160	76%	0.762	82%	0.817	S	S	*	*				72.4	124.7	111.8	-70.9	-175.2	178.7	-173.2	3.1	111.5
3	R	22.7	Very low	23.8	Very low	204 Å²	204	154.5 Å²	154.5	77%	0.77	81%	0.811	S	S	*	*			cis	-175.5	143.3	27.6	-121.3	169.1	-167.1	-169.6	2.1	110.5
4	C	22.4	Very low	24.1	Very low	109 Å²	109	151 Å²	151	74%	0.736	80%	0.802	S	S	*	*			trans	-58.7	168.2	145.9	-63.3	0	0	0	0	111.4
5	P	29.9	Very low	23.9	Very low	113 Å²	113	153.5 Å²	153.5	73%	0.734	80%	0.803	S	S	*	*				-132.9	129.4	107.1	13.8	7.5	0	0	0	111.8
6	L	23.5	Very low	23.8	Very low	147 Å²	147	153.3 Å²	153.3	77%	0.77	80%	0.802	S	S	*	*				72.3	106.3	86.8	-78.5	147.1	0	0	0	112.8
7	L	23.2	Very low	23.7	Very low	155 Å²	155	150.7 Å²	150.7	81%	0.812	80%	0.8	S	S	*	*				73.9	117.6	74.6	-94	155.5	0	0	0	115
8	A	23.1	Very low	23.7	Very low	89 Å²	89	149.4 Å²	149.4	74%	0.736	80%	0.801	S	S	*	*				173.1	105.5	127.3	0	0	0	0	0	109.2
9	R	22.3	Very low	23.6	Very low	227 Å²	227	148.1 Å²	148.1	86%	0.857	80%	0.799	S	S	*	*				83	120.5	91.5	-82.8	-172	-176.4	-162.2	1.2	113.8
10	L	22	Very low	23.6	Very low	171 Å²	171	148.6 Å²	148.6	90%	0.895	80%	0.8	S	S	*	*				173.6	115.6	117.1	-88.4	154.7	0	0	0	111
11	N	20.8	Very low	23.7	Very low	153 Å²	153	146 Å²	146	82%	0.818	79%	0.791	S	S	*	*			trans	-85.7	169.8	152	-104.4	0.5	0	0	0	107.8
12	P	28	Very low	23.4	Very low	122 Å²	122	147.5 Å²	147.5	79%	0.792	79%	0.785	S	S	*	*			cis	-143.6	-176.6	29.7	33.3	-8	0	0	0	116.8
13	A	22.1	Very low	23.4	Very low	89 Å²	89	146.1 Å²	146.1	74%	0.736	79%	0.786	S	S	*	*			trans	-51.9	175.7	-179.4	0	0	0	0	0	116.2
14	P	28.3	Very low	23.5	Very low	105 Å²	105	145.3 Å²	145.3	68%	0.682	79%	0.794	S	S	*	*				-154.3	178	56.9	33.5	-6.7	0	0	0	118.5
15	F	21	Very low	23.5	Very low	188 Å²	188	151.1 Å²	151.1	83%	0.825	80%	0.8	S	S	*	*			trans	88.1	132	154.1	-82.1	-77.5	0	0	0	122.9
16	L	22.6	Very low	23.2	Very low	151 Å²	151	151.1 Å²	151.1	79%	0.791	80%	0.803	S	S	*	*			trans	96.2	87.5	149.9	-68	153	0	0	0	118.7
17	S	22	Very low	23.3	Very low	109 Å²	109	150.4 Å²	150.4	76%	0.762	81%	0.805	S	S	*	*			trans	-49.2	145.5	142.3	15	0	0	0	0	112.5
18	P	23.7	Very low	23.2	Very low	127 Å²	127	146.4 Å²	146.4	83%	0.825	80%	0.801	S	S	*	*				-129.5	160.6	128.1	33.2	-20.4	0	0	0	112.8
19	V	21.6	Very low	23.1	Very low	125 Å²	125	147.4 Å²	147.4	76%	0.758	80%	0.802	S	S	*	*			trans	-83.3	151.5	-169.7	159.7	0	0	0	0	111.8
20	L	23.6	Very low	23.2	Very low	157 Å²	157	142.4 Å²	142.4	82%	0.822	80%	0.797	S	S	*	*			trans	92.4	160.7	165.2	-64.2	148.6	0	0	0	118.4
21	P	25.1	Very low	23.2	Very low	95 Å²	95	140.6 Å²	140.6	62%	0.617	80%	0.797	S	S	*	*			cis	-129	158.1	-49.4	32.7	-16.7	0	0	0	111.5	H23	P21-H23 PolarHBondContact O-N 3.4Å
22	W	22.5	Very low	23.2	Very low	260 Å²	260	138 Å²	138	99%	0.985	79%	0.791	S	S	*	*			trans	-67.8	93.8	170.8	-81.5	52.9	0	0	0	110.1
23	H	21.8	Very low	22.9	Very low	172 Å²	172	142.3 Å²	142.3	80%	0.796	80%	0.798	S	S	*	*			trans	-103.5	103.6	162.7	-107.3	25.7	0	0	0	108	P21 R25	P21-H23 PolarHBondContact O-N 3.4Å; H23-R25 PolarHBondContact O-N 3.1Å; H23-R25 VanDerWaalsContact O-N 3.16Å
24	M	24.3	Very low	23	Very low	188 Å²	188	144.3 Å²	144.3	93%	0.926	80%	0.8	S	S	*	*			trans	-71.8	103.5	170	-136.1	171.5	-177.3	0	0	107.5	S26	M24-S26 PolarHBondContact O-N 3.37Å
25	R	22.7	Very low	22.7	Very low	231 Å²	231	142.4 Å²	142.4	87%	0.872	80%	0.8	S	S	*	*			trans	-69	113.1	171.2	-89.5	-174.7	-178.7	-154.6	0.1	109.3	H23 T27	H23-R25 PolarHBondContact O-N 3.1Å; H23-R25 VanDerWaalsContact O-N 3.16Å; R25-T27 PolarHBondContact O-N 3.43Å
26	S	24.2	Very low	22.8	Very low	113 Å²	113	137.8 Å²	137.8	79%	0.79	80%	0.797	S	S	*	*			trans	-47.8	122.2	147.5	158.2	0	0	0	0	110.8	M24	M24-S26 PolarHBondContact O-N 3.37Å
27	T	24	Very low	22.8	Very low	131 Å²	131	137 Å²	137	80%	0.804	80%	0.798	S	S	*	*			trans	-141.1	103.6	149.5	48.7	0	0	0	0	107.7	R25	R25-T27 PolarHBondContact O-N 3.43Å
28	G	21.4	Very low	22.9	Very low	71 Å²	71	138.2 Å²	138.2	73%	0.732	80%	0.796	S	S	*	*			trans	-74.4	156.6	165.7	0	0	0	0	0	111.7
29	S	22.2	Very low	23	Very low	110 Å²	110	142.6 Å²	142.6	77%	0.769	80%	0.803	S	S	*	*			trans	-157	102.9	146.3	-159.6	0	0	0	0	111
30	V	23.1	Very low	23.2	Very low	122 Å²	122	142.7 Å²	142.7	74%	0.739	80%	0.803	S	S	*	*			trans	63.8	112.2	131.7	-172	0	0	0	0	119.3
31	C	22	Very low	23.3	Very low	134 Å²	134	140.1 Å²	140.1	91%	0.905	79%	0.79	S	S	*	*				-150.9	112.7	111.3	-146.3	0	0	0	0	111.2
32	S	21.4	Very low	23.4	Very low	98 Å²	98	141.6 Å²	141.6	69%	0.685	80%	0.797	S	S	*	*			trans	-104.3	130.8	176	-46.2	0	0	0	0	108.6
33	F	21.6	Very low	23.5	Very low	212 Å²	212	133.9 Å²	133.9	93%	0.93	78%	0.782	S	S	*	*			trans	176.4	116.7	158.6	-111.1	-87.5	0	0	0	103.4
34	V	24.1	Very low	23.9	Very low	131 Å²	131	129 Å²	129	79%	0.794	77%	0.765	S	S	*	*			cis	-157.7	135.8	42.5	164.4	0	0	0	0	107.8
35	G	21.6	Very low	24.2	Very low	66 Å²	66	123.7 Å²	123.7	68%	0.68	74%	0.74	S	S	*	*			trans	-92.9	160.3	165.2	0	0	0	0	0	112.3
36	A	23.6	Very low	24.4	Very low	91 Å²	91	116.5 Å²	116.5	75%	0.752	73%	0.725	S	S	*	*			trans	86.8	99.6	167.1	0	0	0	0	0	117.2
37	T	23.3	Very low	24.7	Very low	134 Å²	134	117.6 Å²	117.6	82%	0.822	72%	0.722	S	S	*	*				-173.5	138.6	111.5	27.3	0	0	0	0	111.8
38	N	23.9	Very low	25	Very low	135 Å²	135	117.9 Å²	117.9	72%	0.722	71%	0.712	S	S	*	*			trans	77.9	95	154.5	-69.8	-12.6	0	0	0	122.1	V40	N38-V40 PolarHBondContact O-N 2.82Å
39	K	25.4	Very low	25.5	Very low	219 Å²	219	119.2 Å²	119.2	95%	0.952	70%	0.698	S	S	*	*	T	Hydrogen-bonded Turn	trans	-40.8	36	155.9	-90.5	177.6	169.6	178.4	0	118.9
40	V	25.1	Very low	25.8	Very low	126 Å²	126	116.2 Å²	116.2	76%	0.764	68%	0.684	S	S	*	*	T	Hydrogen-bonded Turn	trans	-116.3	-4.1	-179.7	-174.2	0	0	0	0	114.1	N38	N38-V40 PolarHBondContact O-N 2.82Å
41	L	26.8	Very low	26.4	Very low	104 Å²	104	117.4 Å²	117.4	55%	0.545	68%	0.679	S	S	.	*			trans	-90.4	-3	-169.9	-93.7	129.3	0	0	0	117.8	S43 T44 D45	L41-S43 VanDerWaalsContact C-N 3.27Å; L41-S43 PolarHBondContact O-N 3.21Å; L41-T44 PolarHBondContact O-N 3.12Å; L41-T44 PolarHBondContact O-OG1 3.28Å; L41-T44 VanDerWaalsContact O-OG1 3.07Å; L41-D45 PolarHBondContact O-N 3.41Å
42	V	27.1	Very low	27.3	Very low	126 Å²	126	113.2 Å²	113.2	76%	0.764	65%	0.647	S	S	*	*	H	α-helix	trans	-68.2	-23	-169.7	-177.2	0	0	0	0	113.7
43	S	25.1	Very low	28.5	Very low	98 Å²	98	110.1 Å²	110.1	69%	0.685	63%	0.627	S	S	*	*	H	α-helix	trans	-92.6	-15.8	-179.3	-57.4	0	0	0	0	114.4	L41 S46	L41-S43 VanDerWaalsContact C-N 3.27Å; L41-S43 PolarHBondContact O-N 3.21Å; S43-S46 PolarHBondContact O-OG 3.49Å
44	T	29.9	Very low	29.9	Very low	70 Å²	70	107.1 Å²	107.1	43%	0.429	62%	0.616	S	S	.	*	H	α-helix	trans	-87	-31.3	176	42.9	0	0	0	0	111.8	L41 S46 L47 F48	L41-T44 PolarHBondContact O-N 3.12Å; L41-T44 PolarHBondContact O-OG1 3.28Å; L41-T44 VanDerWaalsContact O-OG1 3.07Å; T44-S46 PolarHBondContact O-N 3.49Å; T44-L47 PolarHBondContact O-N 2.99Å; T44-F48 WeakPolarHBondContact O-CD2 3.46Å; T44-F48 PolarHBondContact O-N 2.88Å; T44-F48 VanDerWaalsContact O-N 3.09Å
45	D	29.5	Very low	31.5	Very low	75 Å²	75	104 Å²	104	40%	0.401	59%	0.591	S	S	.	*	H	α-helix	trans	-66.8	-36.4	-177.9	-71.3	-16.4	0	0	0	112.4	L41 L47 F48 F49	L41-D45 PolarHBondContact O-N 3.41Å; D45-L47 PolarHBondContact O-N 3.47Å; D45-F48 CarbonylContact O-C 3.53Å; D45-F48 PolarHBondContact O-N 3.19Å; D45-F48 VanDerWaalsContact O-N 3.15Å; D45-F49 VanDerWaalsContact O-CD2 3.29Å; D45-F49 WeakPolarHBondContact O-CD2 3.42Å; D45-F49 PolarHBondContact O-N 3.09Å
46	S	27.4	Very low	33.2	Very low	81 Å²	81	102.1 Å²	102.1	57%	0.566	57%	0.565	S	S	*	*	H	α-helix	trans	-66.7	-34.6	179.5	53.2	0	0	0	0	113.9	S43 T44 G50	S43-S46 PolarHBondContact O-OG 3.49Å; T44-S46 PolarHBondContact O-N 3.49Å; S46-G50 PolarHBondContact O-N 3.44Å
47	L	30.1	Very low	35.3	Very low	136 Å²	136	98.3 Å²	98.3	71%	0.712	53%	0.532	S	S	*	.	H	α-helix	trans	-76.3	-28.3	172.1	-87	158.3	0	0	0	112.5	T44 D45	T44-L47 PolarHBondContact O-N 2.99Å; D45-L47 PolarHBondContact O-N 3.47Å
48	F	31.5	Very low	37.4	Very low	137 Å²	137	93.4 Å²	93.4	60%	0.601	50%	0.502	S	S	*	.	H	α-helix	trans	-70.9	-43.1	172	-98.8	-94.4	0	0	0	111.6	T44 D45 G50 K51 M52	T44-F48 WeakPolarHBondContact O-CD2 3.46Å; T44-F48 PolarHBondContact O-N 2.88Å; T44-F48 VanDerWaalsContact O-N 3.09Å; D45-F48 CarbonylContact O-C 3.53Å; D45-F48 PolarHBondContact O-N 3.19Å; D45-F48 VanDerWaalsContact O-N 3.15Å; F48-G50 VanDerWaalsContact C-N 3.33Å; F48-G50 PolarHBondContact O-N 3.31Å; F48-K51 PolarHBondContact O-N 2.9Å; F48-M52 WeakPolarHBondContact O-CG 3.42Å; F48-M52 PolarHBondContact O-N 3.45Å
49	F	31.1	Very low	39.6	Very low	99 Å²	99	92.1 Å²	92.1	43%	0.434	50%	0.499	S	S	.	.	H	α-helix	trans	-61.4	-38.3	175.8	-92.5	-88.3	0	0	0	112.6	D45 K51 M52 A53	D45-F49 VanDerWaalsContact O-CD2 3.29Å; D45-F49 WeakPolarHBondContact O-CD2 3.42Å; D45-F49 PolarHBondContact O-N 3.09Å; F49-K51 VanDerWaalsContact C-N 3.33Å; F49-K51 PolarHBondContact O-N 3.26Å; F49-M52 VanDerWaalsContact CA-CE 3.46Å; F49-M52 HydrophobicContact CB-CE 4.14Å; F49-M52 HydrophobicContact CD1-CE 3.81Å; F49-M52 HydrophobicContact CD2-CE 3.8Å; F49-M52 HydrophobicContact CE1-CE 4.15Å; F49-M52 HydrophobicContact CE2-CE 4.13Å; F49-M52 HydrophobicContact CG-CE 3.63Å; F49-M52 HydrophobicContact CZ-CE 4.29Å; F49-M52 PolarHBondContact O-N 3.07Å; F49-A53 PolarHBondContact O-N 3.18Å
50	G	27.9	Very low	41.8	Very low	46 Å²	46	87.4 Å²	87.4	47%	0.474	48%	0.475	S	S	.	.	H	α-helix	trans	-62.5	-34.2	175.7	0	0	0	0	0	114.4	S46 F48	S46-G50 PolarHBondContact O-N 3.44Å; F48-G50 VanDerWaalsContact C-N 3.33Å; F48-G50 PolarHBondContact O-N 3.31Å
51	K	35.8	Very low	44	Very low	148 Å²	148	81.8 Å²	81.8	64%	0.643	44%	0.441	S	S	*	.	H	α-helix	trans	-79.6	-23.8	175.6	-77.1	-174.7	175.4	-176	0	113.5	F48 F49 Y55	F48-K51 PolarHBondContact O-N 2.9Å; F49-K51 VanDerWaalsContact C-N 3.33Å; F49-K51 PolarHBondContact O-N 3.26Å; K51-Y55 WeakPolarHBondContact O-CD2 3.19Å
52	M	41.6	Very low	46.1	Very low	45 Å²	45	78.5 Å²	78.5	22%	0.222	43%	0.428	C	S	.	.	H	α-helix	trans	-74.4	-31.2	180	-71.7	-174	-65.9	0	0	112.3	F48 F49	F48-M52 WeakPolarHBondContact O-CG 3.42Å; F48-M52 PolarHBondContact O-N 3.45Å; F49-M52 VanDerWaalsContact CA-CE 3.46Å; F49-M52 HydrophobicContact CB-CE 4.14Å; F49-M52 HydrophobicContact CD1-CE 3.81Å; F49-M52 HydrophobicContact CD2-CE 3.8Å; F49-M52 HydrophobicContact CE1-CE 4.15Å; F49-M52 HydrophobicContact CE2-CE 4.13Å; F49-M52 HydrophobicContact CG-CE 3.63Å; F49-M52 HydrophobicContact CZ-CE 4.29Å; F49-M52 PolarHBondContact O-N 3.07Å
53	A	45.5	Very low	48.5	Very low	34 Å²	34	79.8 Å²	79.8	28%	0.281	43%	0.426	S	S	.	.	G	3₁₀ helix	trans	-74.5	-20.7	176.5	0	0	0	0	0	114.2	F49 Y55 D56 Y83	F49-A53 PolarHBondContact O-N 3.18Å; A53-Y55 PolarHBondContact O-N 3.49Å; A53-D56 PolarHBondContact O-N 3.46Å; A53-Y83 HydrophobicContact CB-CE1 4.25Å
54	E	52.6	Low	50.7	Low	149 Å²	149	76.8 Å²	76.8	70%	0.696	40%	0.4	S	S	*	.	G	3₁₀ helix	trans	-69.1	-20.9	-178.1	-74.3	-174.4	155.8	0	0	113.4
55	Y	56.6	Low	52.9	Low	66 Å²	66	74.4 Å²	74.4	26%	0.259	39%	0.385	S	S	.	.	G	3₁₀ helix	trans	-100.4	5.3	-177.6	-60.6	-69.1	0	0	0	113.9	K51 A53 L57 P342 V369	K51-Y55 WeakPolarHBondContact O-CD2 3.19Å; A53-Y55 PolarHBondContact O-N 3.49Å; Y55-L57 WeakPolarHBondContact O-CD1 3.45Å; Y55-L57 PolarHBondContact O-N 3.14Å; Y55-L57 VanDerWaalsContact O-N 3.09Å; Y55-P342 VanDerWaalsContact CE1-CD 3.42Å; Y55-P342 HydrophobicContact CE1-CG 3.94Å; Y55-P342 HydrophobicContact CE2-CG 4.37Å; Y55-V369 HydrophobicContact CD2-CG2 3.82Å; Y55-V369 HydrophobicContact CE2-CG2 4.26Å; Y55-V369 HydrophobicContact CG-CG2 4.19Å
56	D	58.4	Low	54.9	Low	25 Å²	25	73.8 Å²	73.8	13%	0.134	38%	0.381	C	S	.	.			trans	-74.6	105.7	-179.3	-75.3	-36.8	0	0	0	111.6	A53 T58 Y83	A53-D56 PolarHBondContact O-N 3.46Å; D56-T58 VanDerWaalsContact C-N 3.26Å; D56-T58 PolarHBondContact O-N 3.47Å; D56-Y83 WeakPolarHBondContact OD2-CE2 3.29Å; D56-Y83 PolarHBondContact OD2-OH 2.94Å
57	L	66.9	Low	57.1	Low	11 Å²	11	76.5 Å²	76.5	6%	0.058	38%	0.379	C	S	.	.			trans	-83	-4.4	179.8	-74.5	134.9	0	0	0	113.2	Y55 T59 R60 I61 H303	Y55-L57 WeakPolarHBondContact O-CD1 3.45Å; Y55-L57 PolarHBondContact O-N 3.14Å; Y55-L57 VanDerWaalsContact O-N 3.09Å; L57-T59 VanDerWaalsContact C-N 3.28Å; L57-T59 PolarHBondContact O-N 2.84Å; L57-R60 PolarHBondContact O-N 3.2Å; L57-I61 HydrophobicContact CB-CD1 3.65Å; L57-I61 HydrophobicContact CB-CG1 4.16Å; L57-I61 WeakPolarHBondContact O-CB 3.32Å; L57-I61 WeakPolarHBondContact O-CG1 3.22Å; L57-I61 PolarHBondContact O-N 3.37Å; L57-H303 HydrophobicContact CD2-CB 3.15Å
58	T	67.4	Low	59.1	Low	32 Å²	32	70.4 Å²	70.4	20%	0.196	35%	0.347	C	S	.	.	H	α-helix	trans	-58.6	-39.7	-172.8	-45.6	0	0	0	0	111.9	D56 A62 L73 L77	D56-T58 VanDerWaalsContact C-N 3.26Å; D56-T58 PolarHBondContact O-N 3.47Å; T58-A62 WeakPolarHBondContact O-CB 3.44Å; T58-A62 PolarHBondContact O-N 3.48Å; T58-L73 HydrophobicContact CG2-CB 4.11Å; T58-L73 HydrophobicContact CG2-CD1 4.35Å; T58-L77 HydrophobicContact CG2-CD1 3.71Å
59	T	68.8	Low	61	Low	107 Å²	107	64 Å²	64	66%	0.656	32%	0.319	S	S	*	.	H	α-helix	trans	-65.2	-41.7	176.8	54.7	0	0	0	0	111.8	L57 H63	L57-T59 VanDerWaalsContact C-N 3.28Å; L57-T59 PolarHBondContact O-N 2.84Å; T59-H63 PolarHBondContact O-CE1 2.91Å; T59-H63 PolarHBondContact O-ND1 2.82Å
60	R	71.9	Confident	63.2	Low	121 Å²	121	59.8 Å²	59.8	46%	0.457	30%	0.302	S	S	.	.	H	α-helix	trans	-73.4	-40.5	179.8	-169	174.9	-68.7	175.1	0.5	112	L57 H63 F64 H303	L57-R60 PolarHBondContact O-N 3.2Å; R60-H63 PolarHBondContact O-N 3.13Å; R60-F64 HydrophobicContact CG-CE2 4.44Å; R60-F64 WeakPolarHBondContact O-CD2 3.27Å; R60-F64 WeakPolarHBondContact O-CE2 3.48Å; R60-H303 WeakPolarHBondContact CD-ND1 3.49Å
61	I	72.8	Confident	65.5	Low	8 Å²	8	59.2 Å²	59.2	4%	0.041	29%	0.286	C	S	.	.	H	α-helix	trans	-68.6	-37.5	176.9	-69	171	0	0	0	110.4	L57 H63 F64 L65 Y307	L57-I61 HydrophobicContact CB-CD1 3.65Å; L57-I61 HydrophobicContact CB-CG1 4.16Å; L57-I61 WeakPolarHBondContact O-CB 3.32Å; L57-I61 WeakPolarHBondContact O-CG1 3.22Å; L57-I61 PolarHBondContact O-N 3.37Å; I61-H63 PolarHBondContact O-N 3.17Å; I61-F64 PolarHBondContact O-N 2.94Å; I61-L65 HydrophobicContact CG2-CD1 3.46Å; I61-L65 VanDerWaalsContact CG2-CD1 3.46Å; I61-L65 HydrophobicContact CG2-CG 3.99Å; I61-L65 WeakPolarHBondContact O-CG 3.32Å; I61-L65 PolarHBondContact O-N 3.16Å; I61-Y307 HydrophobicContact CD1-CE2 4.01Å
62	A	70.5	Confident	67.4	Low	34 Å²	34	54.6 Å²	54.6	28%	0.281	27%	0.271	S	S	.	.	H	α-helix	trans	-58	-30.8	178.1	0	0	0	0	0	113.3	T58 F64 L65 V70	T58-A62 WeakPolarHBondContact O-CB 3.44Å; T58-A62 PolarHBondContact O-N 3.48Å; A62-F64 PolarHBondContact O-N 3.31Å; A62-L65 PolarHBondContact O-N 3.03Å; A62-V70 HydrophobicContact CB-CG1 3.6Å
63	H	77.1	Confident	68.8	Low	153 Å²	153	52.9 Å²	52.9	71%	0.708	26%	0.263	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.2	-20.7	175.7	-73.9	79.5	0	0	0	113.5	T59 R60 I61	T59-H63 PolarHBondContact O-CE1 2.91Å; T59-H63 PolarHBondContact O-ND1 2.82Å; R60-H63 PolarHBondContact O-N 3.13Å; I61-H63 PolarHBondContact O-N 3.17Å
64	F	71.6	Confident	70.1	Confident	36 Å²	36	52.8 Å²	52.8	16%	0.158	26%	0.257	C	S	.	.	T	Hydrogen-bonded Turn	trans	-105.2	2.5	-179.5	-56.4	-71.4	0	0	0	112.8	R60 I61 A62 T263 W264 H267 W268 C301	R60-F64 HydrophobicContact CG-CE2 4.44Å; R60-F64 WeakPolarHBondContact O-CD2 3.27Å; R60-F64 WeakPolarHBondContact O-CE2 3.48Å; I61-F64 PolarHBondContact O-N 2.94Å; A62-F64 PolarHBondContact O-N 3.31Å; F64-T263 HydrophobicContact CD1-CG2 3.94Å; F64-T263 HydrophobicContact CE1-CG2 3.86Å; F64-W264 AromaticContact CD1-CD1 3.72Å; F64-W264 AromaticContact CD1-NE1 3.82Å; F64-H267 HydrophobicContact CB-CB 4.19Å; F64-H267 AromaticContact CD2-CD2 3.95Å; F64-H267 AromaticContact CD2-CE1 3.67Å; F64-H267 AromaticContact CD2-NE2 3.45Å; F64-H267 WeakPolarHBondContact CD2-NE2 3.47Å; F64-H267 AromaticContact CG-CE1 3.79Å; F64-H267 AromaticContact CG-ND1 3.95Å; F64-H267 AromaticContact CG-NE2 3.94Å; F64-W268 PolarHBondContact O-NE1 3.07Å; F64-C301 WeakPolarHBondContact CZ-SG 3.33Å
65	L	75	Confident	71	Confident	20 Å²	20	50.8 Å²	50.8	11%	0.105	25%	0.248	C	C	.	.	S	Bend	trans	-113.4	157.1	-177.9	-67.8	176.6	0	0	0	112.4	I61 A62 L69 V70 L73 H267 W268 F271	I61-L65 HydrophobicContact CG2-CD1 3.46Å; I61-L65 VanDerWaalsContact CG2-CD1 3.46Å; I61-L65 HydrophobicContact CG2-CG 3.99Å; I61-L65 WeakPolarHBondContact O-CG 3.32Å; I61-L65 PolarHBondContact O-N 3.16Å; A62-L65 PolarHBondContact O-N 3.03Å; L65-L69 HydrophobicContact CB-CB 4.46Å; L65-L69 HydrophobicContact CD2-CD1 4.35Å; L65-V70 HydrophobicContact CB-CG1 4.26Å; L65-V70 HydrophobicContact CD1-CG1 4.31Å; L65-L73 HydrophobicContact CD1-CD1 3.76Å; L65-H267 HydrophobicContact CD2-CB 4.4Å; L65-W268 HydrophobicContact CD2-CG 4.36Å; L65-F271 HydrophobicContact CD1-CE2 3.69Å; L65-F271 HydrophobicContact CD1-CZ 3.49Å; L65-F271 VanDerWaalsContact CD1-CZ 3.49Å; L65-F271 HydrophobicContact CD2-CD2 4.23Å; L65-F271 HydrophobicContact CD2-CE2 3.37Å; L65-F271 HydrophobicContact CD2-CZ 3.9Å; L65-F271 HydrophobicContact CG-CE2 4.17Å; L65-F271 HydrophobicContact CG-CZ 4.36Å
66	D	72.5	Confident	71.7	Confident	61 Å²	61	49.5 Å²	49.5	33%	0.326	24%	0.244	S	C	.	.			trans	-72.2	150.6	169.2	-103.9	-8.4	0	0	0	111.7	H68 L69 V70 Y190 W268	D66-H68 PolarHBondContact O-N 3.33Å; D66-H68 VanDerWaalsContact O-N 3.08Å; D66-L69 HydrophobicContact CB-CD1 4.37Å; D66-L69 HydrophobicContact CB-CG 4.49Å; D66-L69 PolarHBondContact O-N 3.41Å; D66-V70 PolarHBondContact O-N 3.28Å; D66-Y190 PolarHBondContact OD2-OH 3.3Å; D66-W268 HydrophobicContact CB-CH2 4.01Å; D66-W268 HydrophobicContact CB-CZ2 3.83Å; D66-W268 WeakPolarHBondContact OD2-CH2 3.47Å
67	R	73.2	Confident	72.3	Confident	138 Å²	138	48.9 Å²	48.9	52%	0.521	24%	0.241	S	C	.	.	T	Hydrogen-bonded Turn	trans	-54.2	-30.6	-179.2	-65.5	-177.7	172.2	91.5	-4.1	113.6	V70 F71 L95 T99	R67-V70 WeakPolarHBondContact O-CG2 3.48Å; R67-F71 WeakPolarHBondContact O-CD2 3.13Å; R67-F71 VanDerWaalsContact O-CE2 3.24Å; R67-F71 WeakPolarHBondContact O-CE2 3.29Å; R67-L95 HydrophobicContact CB-CD1 4.19Å; R67-L95 HydrophobicContact CG-CD1 4.06Å; R67-T99 HydrophobicContact CB-CG2 4.08Å
68	H	72.3	Confident	72.3	Confident	8 Å²	8	49.5 Å²	49.5	4%	0.037	25%	0.246	C	C	.	.	T	Hydrogen-bonded Turn	trans	-79.4	-28.2	178.5	-72.2	-111.4	0	0	0	112.9	D66 F71 P72 Y190 Y195 L229	D66-H68 PolarHBondContact O-N 3.33Å; D66-H68 VanDerWaalsContact O-N 3.08Å; H68-F71 PolarHBondContact O-N 2.81Å; H68-P72 WeakPolarHBondContact O-CD 3.41Å; H68-Y190 HydrophobicContact CB-CE1 4.45Å; H68-Y190 AromaticContact CD2-CE1 3.7Å; H68-Y190 PolarHBondContact CE1-O 3.05Å; H68-Y195 AromaticContact ND1-CE1 3.73Å; H68-Y195 AromaticContact ND1-CZ 3.79Å; H68-Y195 PolarHBondContact ND1-OH 2.96Å; H68-L229 HydrophobicContact CB-CD1 3.72Å; H68-L229 HydrophobicContact CB-CD2 4.45Å
69	L	72.5	Confident	72.6	Confident	2 Å²	2	53.4 Å²	53.4	1%	0.01	27%	0.269	C	S	.	.	T	Hydrogen-bonded Turn	trans	-79.9	-17.2	-178.7	-68.4	175.5	0	0	0	113.4	L65 D66 P72 I228 L229 W268	L65-L69 HydrophobicContact CB-CB 4.46Å; L65-L69 HydrophobicContact CD2-CD1 4.35Å; D66-L69 HydrophobicContact CB-CD1 4.37Å; D66-L69 HydrophobicContact CB-CG 4.49Å; D66-L69 PolarHBondContact O-N 3.41Å; L69-P72 WeakPolarHBondContact O-CD 3.36Å; L69-I228 HydrophobicContact CD2-CB 4.08Å; L69-I228 HydrophobicContact CD2-CG2 3.5Å; L69-L229 HydrophobicContact CD2-CD1 4.48Å; L69-L229 HydrophobicContact CD2-CD2 3.93Å; L69-L229 HydrophobicContact CD2-CG 3.88Å; L69-W268 HydrophobicContact CD1-CD2 4.04Å; L69-W268 HydrophobicContact CD1-CE3 4.04Å; L69-W268 HydrophobicContact CD1-CH2 4.31Å; L69-W268 HydrophobicContact CD1-CZ2 4.24Å; L69-W268 HydrophobicContact CD1-CZ3 4.21Å
70	V	77.3	Confident	72.4	Confident	12 Å²	12	51.6 Å²	51.6	7%	0.073	25%	0.253	C	S	.	.	H	α-helix	trans	-79	-17.9	172.1	-77.6	0	0	0	0	112.8	A62 L65 D66 R67 L73 L74 L95	A62-V70 HydrophobicContact CB-CG1 3.6Å; L65-V70 HydrophobicContact CB-CG1 4.26Å; L65-V70 HydrophobicContact CD1-CG1 4.31Å; D66-V70 PolarHBondContact O-N 3.28Å; R67-V70 WeakPolarHBondContact O-CG2 3.48Å; V70-L73 PolarHBondContact O-N 2.84Å; V70-L74 WeakPolarHBondContact O-CB 3.3Å; V70-L74 WeakPolarHBondContact O-CG 3.32Å; V70-L74 PolarHBondContact O-N 2.93Å; V70-L95 HydrophobicContact CB-CD2 4.47Å; V70-L95 HydrophobicContact CG2-CD1 4.39Å; V70-L95 HydrophobicContact CG2-CD2 3.45Å; V70-L95 VanDerWaalsContact CG2-CD2 3.45Å
71	F	74.7	Confident	71.9	Confident	33 Å²	33	53 Å²	53	15%	0.145	26%	0.264	C	S	.	.	H	α-helix	trans	-63.7	-48	178.2	-67.2	-60.5	0	0	0	113.7	R67 H68 L73 L74 E75 L95 L96 M101	R67-F71 WeakPolarHBondContact O-CD2 3.13Å; R67-F71 VanDerWaalsContact O-CE2 3.24Å; R67-F71 WeakPolarHBondContact O-CE2 3.29Å; H68-F71 PolarHBondContact O-N 2.81Å; F71-L73 PolarHBondContact O-N 2.92Å; F71-L74 PolarHBondContact O-N 3.29Å; F71-E75 WeakPolarHBondContact O-CB 3.17Å; F71-E75 PolarHBondContact O-N 2.78Å; F71-L95 HydrophobicContact CD1-CD2 4.03Å; F71-L95 HydrophobicContact CE1-CD2 3.49Å; F71-L95 VanDerWaalsContact CE1-CD2 3.49Å; F71-L95 HydrophobicContact CE1-CG 4.09Å; F71-L95 HydrophobicContact CE2-CD2 4.45Å; F71-L95 HydrophobicContact CZ-CD2 3.73Å; F71-L95 HydrophobicContact CZ-CG 4Å; F71-L96 HydrophobicContact CE1-CD2 3.69Å; F71-L96 HydrophobicContact CE1-CG 3.76Å; F71-L96 HydrophobicContact CZ-CD2 3.61Å; F71-L96 HydrophobicContact CZ-CG 4.03Å; F71-M101 HydrophobicContact CD2-CE 3.63Å; F71-M101 HydrophobicContact CE1-CE 4.49Å; F71-M101 HydrophobicContact CE2-CE 3.15Å; F71-M101 HydrophobicContact CZ-CE 3.66Å
72	P	75.3	Confident	71.4	Confident	51 Å²	51	53.6 Å²	53.6	33%	0.331	27%	0.267	S	S	.	.	H	α-helix	trans	-58.5	-35.5	174.5	-25.3	34.9	0	0	0	113.1	H68 L69 F76 F374	H68-P72 WeakPolarHBondContact O-CD 3.41Å; L69-P72 WeakPolarHBondContact O-CD 3.36Å; P72-F76 WeakPolarHBondContact O-CB 3.46Å; P72-F76 PolarHBondContact O-N 3.48Å; P72-F374 HydrophobicContact CB-CZ 4.18Å
73	L	72.7	Confident	70.9	Confident	9 Å²	9	56.3 Å²	56.3	5%	0.047	27%	0.271	C	S	.	.	H	α-helix	trans	-67.8	-43.9	176.8	-63.1	179.5	0	0	0	111.7	T58 L65 V70 F71 F76 L77 F271 F374 F375	T58-L73 HydrophobicContact CG2-CB 4.11Å; T58-L73 HydrophobicContact CG2-CD1 4.35Å; L65-L73 HydrophobicContact CD1-CD1 3.76Å; V70-L73 PolarHBondContact O-N 2.84Å; F71-L73 PolarHBondContact O-N 2.92Å; L73-F76 PolarHBondContact O-N 2.87Å; L73-L77 WeakPolarHBondContact O-CG 3.48Å; L73-L77 PolarHBondContact O-N 3.45Å; L73-F271 HydrophobicContact CD1-CZ 4.14Å; L73-F374 HydrophobicContact CD2-CB 3.8Å; L73-F374 HydrophobicContact CD2-CD1 3.48Å; L73-F374 VanDerWaalsContact CD2-CD1 3.48Å; L73-F374 HydrophobicContact CD2-CD2 4.47Å; L73-F374 HydrophobicContact CD2-CE1 4.13Å; L73-F374 HydrophobicContact CD2-CG 3.67Å; L73-F375 HydrophobicContact CD2-CE2 4.1Å; L73-F375 HydrophobicContact CD2-CZ 4.11Å
74	L	72.1	Confident	70.5	Confident	32 Å²	32	53.5 Å²	53.5	17%	0.168	26%	0.261	C	S	.	.	H	α-helix	trans	-68.2	-34.6	176.8	-70.3	174.8	0	0	0	112.2	V70 F71 L77 S78 L88 K92 L95	V70-L74 WeakPolarHBondContact O-CB 3.3Å; V70-L74 WeakPolarHBondContact O-CG 3.32Å; V70-L74 PolarHBondContact O-N 2.93Å; F71-L74 PolarHBondContact O-N 3.29Å; L74-L77 HydrophobicContact CD2-CD1 4.3Å; L74-L77 PolarHBondContact O-N 3.15Å; L74-S78 PolarHBondContact O-N 3.09Å; L74-S78 PolarHBondContact O-OG 3.41Å; L74-L88 HydrophobicContact CB-CD2 4.45Å; L74-L88 HydrophobicContact CD2-CG 4.47Å; L74-K92 HydrophobicContact CB-CG 4.2Å; L74-K92 HydrophobicContact CD1-CG 3.98Å; L74-L95 HydrophobicContact CD1-CD2 4.06Å
75	E	71	Confident	70.1	Confident	108 Å²	108	57.7 Å²	57.7	51%	0.505	28%	0.281	S	S	.	.	H	α-helix	trans	-66.3	-42	174.5	-165.4	63.1	-162.2	0	0	111.5	F71 L77 S78 V79 K92	F71-E75 WeakPolarHBondContact O-CB 3.17Å; F71-E75 PolarHBondContact O-N 2.78Å; E75-L77 VanDerWaalsContact C-N 3.34Å; E75-L77 PolarHBondContact O-N 3.2Å; E75-S78 WeakPolarHBondContact O-CB 3.39Å; E75-S78 PolarHBondContact O-N 3.18Å; E75-V79 WeakPolarHBondContact O-CG2 3.11Å; E75-V79 PolarHBondContact O-N 3.43Å; E75-K92 IonicContact OE2-NZ 2.65Å; E75-K92 PolarHBondContact OE2-NZ 3.48Å
76	F	71.2	Confident	69.8	Low	39 Å²	39	63.5 Å²	63.5	17%	0.171	31%	0.305	C	S	.	.	H	α-helix	trans	-62.8	-41	174.2	179.4	-102.1	0	0	0	112.7	P72 L73 S78 V79 K80 N372 F374 V377	P72-F76 WeakPolarHBondContact O-CB 3.46Å; P72-F76 PolarHBondContact O-N 3.48Å; L73-F76 PolarHBondContact O-N 2.87Å; F76-S78 VanDerWaalsContact C-N 3.31Å; F76-S78 PolarHBondContact O-N 3.35Å; F76-V79 PolarHBondContact O-N 2.8Å; F76-K80 HydrophobicContact CD1-CG 4.31Å; F76-K80 HydrophobicContact CE1-CG 3.97Å; F76-K80 HydrophobicContact CE2-CG 4.39Å; F76-K80 HydrophobicContact CZ-CD 4.43Å; F76-K80 HydrophobicContact CZ-CG 4.03Å; F76-K80 WeakPolarHBondContact O-CG 3.38Å; F76-K80 PolarHBondContact O-N 2.76Å; F76-N372 WeakPolarHBondContact CE1-O 3.42Å; F76-F374 HydrophobicContact CB-CD2 3.46Å; F76-F374 VanDerWaalsContact CB-CD2 3.46Å; F76-F374 HydrophobicContact CB-CE2 3.9Å; F76-F374 HydrophobicContact CB-CG 4.48Å; F76-F374 HydrophobicContact CD1-CB 3.92Å; F76-F374 AromaticContact CD1-CD2 3.96Å; F76-F374 HydrophobicContact CD1-CD2 3.96Å; F76-F374 HydrophobicContact CD1-CG 4.45Å; F76-F374 AromaticContact CD2-CD2 3.67Å; F76-F374 HydrophobicContact CD2-CD2 3.67Å; F76-F374 HydrophobicContact CD2-CE2 4.29Å; F76-F374 HydrophobicContact CE1-CB 4.11Å; F76-F374 HydrophobicContact CE2-CD2 4.33Å; F76-F374 HydrophobicContact CG-CB 4.3Å; F76-F374 AromaticContact CG-CD2 3.44Å; F76-F374 HydrophobicContact CG-CD2 3.44Å; F76-F374 VanDerWaalsContact CG-CD2 3.44Å; F76-F374 HydrophobicContact CG-CE2 4.24Å; F76-F374 HydrophobicContact CG-CG 4.35Å; F76-V377 HydrophobicContact CE2-CG2 4.37Å; F76-V377 HydrophobicContact CZ-CG2 4.12Å
77	L	71.6	Confident	69.7	Low	12 Å²	12	66.3 Å²	66.3	6%	0.063	32%	0.317	C	S	.	.	H	α-helix	trans	-64.1	-35.1	174.3	-74.6	163.8	0	0	0	112.3	T58 L73 L74 E75 K80 E81 Y83 L88	T58-L77 HydrophobicContact CG2-CD1 3.71Å; L73-L77 WeakPolarHBondContact O-CG 3.48Å; L73-L77 PolarHBondContact O-N 3.45Å; L74-L77 HydrophobicContact CD2-CD1 4.3Å; L74-L77 PolarHBondContact O-N 3.15Å; E75-L77 VanDerWaalsContact C-N 3.34Å; E75-L77 PolarHBondContact O-N 3.2Å; L77-K80 PolarHBondContact O-N 3.17Å; L77-E81 PolarHBondContact O-N 3.29Å; L77-Y83 HydrophobicContact CD2-CE2 4.44Å; L77-L88 HydrophobicContact CB-CD1 3.66Å
78	S	67.5	Low	69.5	Low	24 Å²	24	60.6 Å²	60.6	17%	0.168	30%	0.297	C	S	.	.	H	α-helix	trans	-61.2	-46.8	171.2	-72	0	0	0	0	112	L74 E75 F76 K80 E81 L88 K92	L74-S78 PolarHBondContact O-N 3.09Å; L74-S78 PolarHBondContact O-OG 3.41Å; E75-S78 WeakPolarHBondContact O-CB 3.39Å; E75-S78 PolarHBondContact O-N 3.18Å; F76-S78 VanDerWaalsContact C-N 3.31Å; F76-S78 PolarHBondContact O-N 3.35Å; S78-K80 PolarHBondContact O-N 2.99Å; S78-E81 PolarHBondContact O-N 3.28Å; S78-L88 WeakPolarHBondContact OG-CD2 3.46Å; S78-K92 PolarHBondContact OG-NZ 3.18Å
79	V	72.9	Confident	69.4	Low	113 Å²	113	60.9 Å²	60.9	69%	0.685	30%	0.298	S	S	*	.	H	α-helix	trans	-65.6	-28.8	-179.7	173.7	0	0	0	0	112.1	E75 F76	E75-V79 WeakPolarHBondContact O-CG2 3.11Å; E75-V79 PolarHBondContact O-N 3.43Å; F76-V79 PolarHBondContact O-N 2.8Å
80	K	65	Low	69.4	Low	70 Å²	70	64.9 Å²	64.9	30%	0.304	32%	0.317	S	S	.	.	H	α-helix	trans	-84.2	-12.2	-179.9	-74.5	-73.7	-169.3	166.6	0	114.2	F76 L77 S78 I82 V371	F76-K80 HydrophobicContact CD1-CG 4.31Å; F76-K80 HydrophobicContact CE1-CG 3.97Å; F76-K80 HydrophobicContact CE2-CG 4.39Å; F76-K80 HydrophobicContact CZ-CD 4.43Å; F76-K80 HydrophobicContact CZ-CG 4.03Å; F76-K80 WeakPolarHBondContact O-CG 3.38Å; F76-K80 PolarHBondContact O-N 2.76Å; L77-K80 PolarHBondContact O-N 3.17Å; S78-K80 PolarHBondContact O-N 2.99Å; K80-I82 HydrophobicContact CB-CD1 3.96Å; K80-I82 HydrophobicContact CB-CG1 3.93Å; K80-I82 PolarHBondContact O-N 2.87Å; K80-I82 VanDerWaalsContact O-N 3.09Å; K80-V371 WeakPolarHBondContact CE-O 3.34Å; K80-V371 PolarHBondContact NZ-O 3.39Å
81	E	62.1	Low	69.1	Low	150 Å²	150	66 Å²	66	70%	0.701	33%	0.331	S	S	*	.	T	Hydrogen-bonded Turn	trans	49.9	32.5	178.2	-62.7	-178.3	174.3	0	0	114.5	L77 S78 Y83	L77-E81 PolarHBondContact O-N 3.29Å; S78-E81 PolarHBondContact O-N 3.28Å; E81-Y83 VanDerWaalsContact C-N 3.33Å
82	I	61.1	Low	68.9	Low	21 Å²	21	65 Å²	65	11%	0.108	33%	0.327	C	S	.	.			trans	-73.2	-31	-179.5	-58.3	170.9	0	0	0	110.8	K80 N372	K80-I82 HydrophobicContact CB-CD1 3.96Å; K80-I82 HydrophobicContact CB-CG1 3.93Å; K80-I82 PolarHBondContact O-N 2.87Å; K80-I82 VanDerWaalsContact O-N 3.09Å; I82-N372 HydrophobicContact CD1-CB 4.1Å
83	Y	60.6	Low	68.7	Low	90 Å²	90	64.2 Å²	64.2	35%	0.353	32%	0.319	S	S	.	.	S	Bend	trans	-113.2	162.1	177.7	-66.1	-83.4	0	0	0	111.6	A53 D56 L77 E81 E85	A53-Y83 HydrophobicContact CB-CE1 4.25Å; D56-Y83 WeakPolarHBondContact OD2-CE2 3.29Å; D56-Y83 PolarHBondContact OD2-OH 2.94Å; L77-Y83 HydrophobicContact CD2-CE2 4.44Å; E81-Y83 VanDerWaalsContact C-N 3.33Å; Y83-E85 PolarHBondContact O-N 3.39Å; Y83-E85 VanDerWaalsContact O-N 3.15Å
84	N	67.8	Low	68.7	Low	94 Å²	94	68.9 Å²	68.9	50%	0.503	34%	0.344	S	S	.	.			trans	-59.9	118.4	171.5	-165.4	-6.6	0	0	0	109.6	K86 E87 L88	N84-K86 PolarHBondContact O-N 3.02Å; N84-E87 HydrophobicContact CB-CG 4.48Å; N84-E87 PolarHBondContact O-N 3.11Å; N84-L88 PolarHBondContact O-N 3.48Å
85	E	63.9	Low	68.7	Low	125 Å²	125	69.1 Å²	69.1	58%	0.584	35%	0.346	S	S	*	.	H	α-helix	trans	-52.7	-32.4	-174.3	-162.7	-172.7	173.3	0	0	112	Y83 L88 L89	Y83-E85 PolarHBondContact O-N 3.39Å; Y83-E85 VanDerWaalsContact O-N 3.15Å; E85-L88 PolarHBondContact O-N 3.28Å; E85-L89 HydrophobicContact CG-CD1 3.9Å; E85-L89 HydrophobicContact CG-CG 4.34Å; E85-L89 VanDerWaalsContact O-CB 3.24Å; E85-L89 WeakPolarHBondContact O-CB 3.42Å; E85-L89 WeakPolarHBondContact O-CD1 3.26Å; E85-L89 WeakPolarHBondContact O-CG 3.3Å; E85-L89 PolarHBondContact O-N 2.86Å
86	K	67.8	Low	68.6	Low	141 Å²	141	64.3 Å²	64.3	61%	0.613	32%	0.323	S	S	*	.	H	α-helix	trans	-67.2	-40.7	179.6	-63	-176	-179.4	-177.5	0	114	N84 L88 Q90 L112	N84-K86 PolarHBondContact O-N 3.02Å; K86-L88 VanDerWaalsContact C-N 3.35Å; K86-Q90 WeakPolarHBondContact O-CB 3.32Å; K86-Q90 VanDerWaalsContact O-CG 3.28Å; K86-Q90 WeakPolarHBondContact O-CG 3.43Å; K86-Q90 PolarHBondContact O-N 2.78Å; K86-L112 HydrophobicContact CB-CD1 4.32Å
87	E	70.5	Confident	68.2	Low	120 Å²	120	64.5 Å²	64.5	56%	0.561	33%	0.33	S	S	*	.	H	α-helix	trans	-71.7	-36.6	178.9	-69.2	176.8	-174.2	0	0	110.5	N84 Q90 G91	N84-E87 HydrophobicContact CB-CG 4.48Å; N84-E87 PolarHBondContact O-N 3.11Å; E87-Q90 PolarHBondContact O-N 2.81Å; E87-G91 PolarHBondContact O-N 3.06Å
88	L	70.8	Confident	68	Low	19 Å²	19	69.4 Å²	69.4	10%	0.099	36%	0.356	C	S	.	.	H	α-helix	trans	-71.7	-39	177.7	-160.3	149.4	0	0	0	111.6	L74 L77 S78 N84 E85 K86 G91 K92	L74-L88 HydrophobicContact CB-CD2 4.45Å; L74-L88 HydrophobicContact CD2-CG 4.47Å; L77-L88 HydrophobicContact CB-CD1 3.66Å; S78-L88 WeakPolarHBondContact OG-CD2 3.46Å; N84-L88 PolarHBondContact O-N 3.48Å; E85-L88 PolarHBondContact O-N 3.28Å; K86-L88 VanDerWaalsContact C-N 3.35Å; L88-G91 PolarHBondContact O-N 3.45Å; L88-K92 HydrophobicContact CD2-CD 4.01Å; L88-K92 VanDerWaalsContact CD2-CE 3.48Å; L88-K92 HydrophobicContact CD2-CG 4.22Å; L88-K92 WeakPolarHBondContact O-CG 3.24Å; L88-K92 PolarHBondContact O-N 2.76Å
89	L	69.8	Low	67.9	Low	14 Å²	14	68.9 Å²	68.9	7%	0.073	35%	0.351	C	S	.	.	H	α-helix	trans	-66.1	-35.8	171.8	-74.7	168.4	0	0	0	112.1	E85 K92 L93 V108 L112	E85-L89 HydrophobicContact CG-CD1 3.9Å; E85-L89 HydrophobicContact CG-CG 4.34Å; E85-L89 VanDerWaalsContact O-CB 3.24Å; E85-L89 WeakPolarHBondContact O-CB 3.42Å; E85-L89 WeakPolarHBondContact O-CD1 3.26Å; E85-L89 WeakPolarHBondContact O-CG 3.3Å; E85-L89 PolarHBondContact O-N 2.86Å; L89-K92 HydrophobicContact CD2-CD 4.42Å; L89-K92 PolarHBondContact O-N 3.14Å; L89-L93 VanDerWaalsContact O-CB 3.3Å; L89-L93 WeakPolarHBondContact O-CB 3.26Å; L89-L93 PolarHBondContact O-N 3.49Å; L89-V108 HydrophobicContact CD2-CG1 3.96Å; L89-L112 HydrophobicContact CB-CD1 3.68Å; L89-L112 HydrophobicContact CD1-CD1 4.17Å
90	Q	71.3	Confident	67.4	Low	85 Å²	85	65.8 Å²	65.8	40%	0.397	33%	0.331	S	S	.	.	H	α-helix	trans	-64.2	-45.3	170.7	-78.4	174.2	-7.5	0	0	111.6	K86 E87 K92 L93 D94 L112	K86-Q90 WeakPolarHBondContact O-CB 3.32Å; K86-Q90 VanDerWaalsContact O-CG 3.28Å; K86-Q90 WeakPolarHBondContact O-CG 3.43Å; K86-Q90 PolarHBondContact O-N 2.78Å; E87-Q90 PolarHBondContact O-N 2.81Å; Q90-K92 VanDerWaalsContact C-N 3.34Å; Q90-K92 PolarHBondContact O-N 3.45Å; Q90-L93 WeakPolarHBondContact O-CB 3.14Å; Q90-L93 PolarHBondContact O-N 3.28Å; Q90-L93 VanDerWaalsContact O-N 3.09Å; Q90-D94 PolarHBondContact O-N 3.4Å; Q90-L112 HydrophobicContact CG-CD1 4.36Å; Q90-L112 HydrophobicContact CG-CD2 3.73Å
91	G	71.3	Confident	67.2	Low	36 Å²	36	63.2 Å²	63.2	37%	0.371	32%	0.32	S	S	.	.	H	α-helix	trans	-62.1	-38.2	174.2	0	0	0	0	0	113.2	E87 L88 L93 L95	E87-G91 PolarHBondContact O-N 3.06Å; L88-G91 PolarHBondContact O-N 3.45Å; G91-L93 VanDerWaalsContact C-N 3.34Å; G91-L95 WeakPolarHBondContact O-CB 3.48Å; G91-L95 PolarHBondContact O-N 3.35Å; G91-L95 VanDerWaalsContact O-N 3.11Å
92	K	70.4	Confident	67.3	Low	13 Å²	13	56.8 Å²	56.8	6%	0.057	29%	0.291	C	S	.	.	H	α-helix	trans	-61.5	-43.1	170.8	-78	178.8	177.3	-179.8	0	110.9	L74 E75 S78 L88 L89 Q90 L95 L96 V108	L74-K92 HydrophobicContact CB-CG 4.2Å; L74-K92 HydrophobicContact CD1-CG 3.98Å; E75-K92 IonicContact OE2-NZ 2.65Å; E75-K92 PolarHBondContact OE2-NZ 3.48Å; S78-K92 PolarHBondContact OG-NZ 3.18Å; L88-K92 HydrophobicContact CD2-CD 4.01Å; L88-K92 VanDerWaalsContact CD2-CE 3.48Å; L88-K92 HydrophobicContact CD2-CG 4.22Å; L88-K92 WeakPolarHBondContact O-CG 3.24Å; L88-K92 PolarHBondContact O-N 2.76Å; L89-K92 HydrophobicContact CD2-CD 4.42Å; L89-K92 PolarHBondContact O-N 3.14Å; Q90-K92 VanDerWaalsContact C-N 3.34Å; Q90-K92 PolarHBondContact O-N 3.45Å; K92-L95 PolarHBondContact O-N 3.28Å; K92-L96 HydrophobicContact CB-CD1 4.48Å; K92-L96 WeakPolarHBondContact O-CB 3.39Å; K92-L96 WeakPolarHBondContact O-CD1 3.38Å; K92-L96 WeakPolarHBondContact O-CG 3.46Å; K92-L96 PolarHBondContact O-N 3.12Å; K92-V108 HydrophobicContact CB-CG1 4.3Å
93	L	70.8	Confident	67.7	Low	34 Å²	34	59.4 Å²	59.4	18%	0.178	31%	0.305	C	S	.	.	H	α-helix	trans	-66.9	-42.5	-178.7	-164.7	163.5	0	0	0	111.7	L89 Q90 G91 L96 S97 V108 Y109 L112	L89-L93 VanDerWaalsContact O-CB 3.3Å; L89-L93 WeakPolarHBondContact O-CB 3.26Å; L89-L93 PolarHBondContact O-N 3.49Å; Q90-L93 WeakPolarHBondContact O-CB 3.14Å; Q90-L93 PolarHBondContact O-N 3.28Å; Q90-L93 VanDerWaalsContact O-N 3.09Å; G91-L93 VanDerWaalsContact C-N 3.34Å; L93-L96 CarbonylContact O-C 3.57Å; L93-L96 PolarHBondContact O-N 2.91Å; L93-S97 WeakPolarHBondContact O-CB 3.31Å; L93-S97 PolarHBondContact O-N 3.47Å; L93-V108 HydrophobicContact CB-CG1 4.33Å; L93-Y109 HydrophobicContact CD1-CD2 3.65Å; L93-Y109 HydrophobicContact CD1-CE2 4.33Å; L93-Y109 HydrophobicContact CD1-CG 4.48Å; L93-L112 HydrophobicContact CD1-CD2 3.9Å
94	D	73.1	Confident	67.9	Low	107 Å²	107	61.4 Å²	61.4	57%	0.572	32%	0.316	S	S	*	.	H	α-helix	trans	-62.8	-44.8	175.9	-73.1	-10.4	0	0	0	111	Q90 L96 S97	Q90-D94 PolarHBondContact O-N 3.4Å; D94-L96 VanDerWaalsContact C-N 3.34Å; D94-L96 PolarHBondContact O-N 3.26Å; D94-S97 PolarHBondContact O-N 3.12Å; D94-S97 PolarHBondContact O-OG 2.97Å
95	L	72.8	Confident	67.8	Low	37 Å²	37	57.1 Å²	57.1	19%	0.194	29%	0.294	C	S	.	.	H	α-helix	trans	-64.5	-37.8	175	-171.8	72.7	0	0	0	112.4	R67 V70 F71 L74 G91 K92 S97 T99	R67-L95 HydrophobicContact CB-CD1 4.19Å; R67-L95 HydrophobicContact CG-CD1 4.06Å; V70-L95 HydrophobicContact CB-CD2 4.47Å; V70-L95 HydrophobicContact CG2-CD1 4.39Å; V70-L95 HydrophobicContact CG2-CD2 3.45Å; V70-L95 VanDerWaalsContact CG2-CD2 3.45Å; F71-L95 HydrophobicContact CD1-CD2 4.03Å; F71-L95 HydrophobicContact CE1-CD2 3.49Å; F71-L95 VanDerWaalsContact CE1-CD2 3.49Å; F71-L95 HydrophobicContact CE1-CG 4.09Å; F71-L95 HydrophobicContact CE2-CD2 4.45Å; F71-L95 HydrophobicContact CZ-CD2 3.73Å; F71-L95 HydrophobicContact CZ-CG 4Å; L74-L95 HydrophobicContact CD1-CD2 4.06Å; G91-L95 WeakPolarHBondContact O-CB 3.48Å; G91-L95 PolarHBondContact O-N 3.35Å; G91-L95 VanDerWaalsContact O-N 3.11Å; K92-L95 PolarHBondContact O-N 3.28Å; L95-S97 VanDerWaalsContact C-N 3.32Å; L95-T99 PolarHBondContact O-N 3.26Å; L95-T99 PolarHBondContact O-OG1 3.23Å
96	L	67.8	Low	67.8	Low	7 Å²	7	51.8 Å²	51.8	4%	0.037	27%	0.269	C	S	.	.	H	α-helix	trans	-72	-25.8	176.2	-75.9	164.7	0	0	0	112.3	F71 K92 L93 D94 D98 T99 M101 F104 A105 V108	F71-L96 HydrophobicContact CE1-CD2 3.69Å; F71-L96 HydrophobicContact CE1-CG 3.76Å; F71-L96 HydrophobicContact CZ-CD2 3.61Å; F71-L96 HydrophobicContact CZ-CG 4.03Å; K92-L96 HydrophobicContact CB-CD1 4.48Å; K92-L96 WeakPolarHBondContact O-CB 3.39Å; K92-L96 WeakPolarHBondContact O-CD1 3.38Å; K92-L96 WeakPolarHBondContact O-CG 3.46Å; K92-L96 PolarHBondContact O-N 3.12Å; L93-L96 CarbonylContact O-C 3.57Å; L93-L96 PolarHBondContact O-N 2.91Å; D94-L96 VanDerWaalsContact C-N 3.34Å; D94-L96 PolarHBondContact O-N 3.26Å; L96-D98 VanDerWaalsContact C-N 3.25Å; L96-D98 PolarHBondContact O-N 3.39Å; L96-T99 WeakPolarHBondContact CA-OG1 3.41Å; L96-T99 PolarHBondContact O-N 3.21Å; L96-T99 PolarHBondContact O-OG1 3.39Å; L96-M101 HydrophobicContact CD2-CB 4.15Å; L96-M101 HydrophobicContact CD2-CE 3.92Å; L96-F104 HydrophobicContact CD2-CB 4.09Å; L96-A105 HydrophobicContact CB-CB 3.92Å; L96-V108 HydrophobicContact CD1-CB 4.14Å; L96-V108 HydrophobicContact CD1-CG2 3.77Å
97	S	63.4	Low	67.9	Low	43 Å²	43	49.1 Å²	49.1	30%	0.301	26%	0.261	S	S	.	.	H	α-helix	trans	-70.8	-25.6	-178.8	78.7	0	0	0	0	113.2	L93 D94 L95 K124	L93-S97 WeakPolarHBondContact O-CB 3.31Å; L93-S97 PolarHBondContact O-N 3.47Å; D94-S97 PolarHBondContact O-N 3.12Å; D94-S97 PolarHBondContact O-OG 2.97Å; L95-S97 VanDerWaalsContact C-N 3.32Å; S97-K124 PolarHBondContact O-NZ 3.4Å; S97-K124 VanDerWaalsContact O-NZ 3.12Å
98	D	66.6	Low	67.7	Low	115 Å²	115	44.3 Å²	44.3	62%	0.615	24%	0.24	S	C	*	.	S	Bend	trans	-91.9	-14.9	175.9	-76.6	-14.2	0	0	0	113.2	L96	L96-D98 VanDerWaalsContact C-N 3.25Å; L96-D98 PolarHBondContact O-N 3.39Å
99	T	65.8	Low	67.5	Low	12 Å²	12	46.1 Å²	46.1	7%	0.074	25%	0.246	C	C	.	.	S	Bend	trans	-102.2	148.2	175.6	57.9	0	0	0	0	110.5	R67 L95 L96 M101	R67-T99 HydrophobicContact CB-CG2 4.08Å; L95-T99 PolarHBondContact O-N 3.26Å; L95-T99 PolarHBondContact O-OG1 3.23Å; L96-T99 WeakPolarHBondContact CA-OG1 3.41Å; L96-T99 PolarHBondContact O-N 3.21Å; L96-T99 PolarHBondContact O-OG1 3.39Å; T99-M101 PolarHBondContact O-N 3.42Å
100	N	61.8	Low	67.5	Low	48 Å²	48	49.5 Å²	49.5	26%	0.257	26%	0.261	S	S	.	.	S	Bend	trans	-78.8	15.7	-177.8	-68.5	-32.8	0	0	0	113.3	V102 V128 E191	N100-V102 WeakPolarHBondContact O-CG2 3.26Å; N100-V102 PolarHBondContact O-N 3.3Å; N100-V128 HydrophobicContact CB-CG1 4.08Å; N100-V128 HydrophobicContact CB-CG2 4.13Å; N100-E191 HydrophobicContact CB-CB 4.24Å; N100-E191 PolarHBondContact ND2-OE2 3.41Å
101	M	61.1	Low	67.4	Low	17 Å²	17	51 Å²	51	8%	0.084	27%	0.271	C	S	.	.			trans	-80.3	63.6	172.8	-66.7	-160.6	-60.3	0	0	111.3	F71 L96 T99 D103 F104 A105 E191	F71-M101 HydrophobicContact CD2-CE 3.63Å; F71-M101 HydrophobicContact CE1-CE 4.49Å; F71-M101 HydrophobicContact CE2-CE 3.15Å; F71-M101 HydrophobicContact CZ-CE 3.66Å; L96-M101 HydrophobicContact CD2-CB 4.15Å; L96-M101 HydrophobicContact CD2-CE 3.92Å; T99-M101 PolarHBondContact O-N 3.42Å; M101-D103 PolarHBondContact O-N 2.95Å; M101-F104 HydrophobicContact CB-CB 4.44Å; M101-F104 HydrophobicContact CB-CD2 4.38Å; M101-F104 PolarHBondContact O-N 3.25Å; M101-F104 HydrophobicContact SD-CD2 4.23Å; M101-A105 PolarHBondContact O-N 3.1Å; M101-E191 WeakPolarHBondContact CG-O 3.38Å
102	V	64.3	Low	67.2	Low	14 Å²	14	50.7 Å²	50.7	9%	0.085	26%	0.261	C	S	.	.	H	α-helix	trans	-64.1	-29.3	-174.1	-130.3	0	0	0	0	112.3	N100 A105 M106 L121 K124 R125 V128	N100-V102 WeakPolarHBondContact O-CG2 3.26Å; N100-V102 PolarHBondContact O-N 3.3Å; V102-A105 PolarHBondContact O-N 3.23Å; V102-M106 VanDerWaalsContact O-CG 3.26Å; V102-M106 WeakPolarHBondContact O-CG 3.27Å; V102-M106 PolarHBondContact O-N 3.19Å; V102-L121 HydrophobicContact CG1-CD2 4.37Å; V102-K124 HydrophobicContact CG1-CB 4.2Å; V102-R125 HydrophobicContact CB-CB 4.33Å; V102-R125 HydrophobicContact CG1-CB 4.28Å; V102-R125 HydrophobicContact CG2-CB 4.47Å; V102-V128 HydrophobicContact CG2-CB 4.34Å; V102-V128 HydrophobicContact CG2-CG1 4.37Å; V102-V128 HydrophobicContact CG2-CG2 4.28Å
103	D	69.3	Low	66.9	Low	76 Å²	76	55.7 Å²	55.7	41%	0.406	28%	0.28	S	S	.	.	H	α-helix	trans	-71.7	-41.5	-179.8	-70.7	-9.6	0	0	0	111.9	M101 M106 D107 R125	M101-D103 PolarHBondContact O-N 2.95Å; D103-M106 HydrophobicContact CB-CE 4.41Å; D103-M106 PolarHBondContact O-N 2.95Å; D103-M106 WeakPolarHBondContact OD1-CE 3.35Å; D103-D107 PolarHBondContact O-N 2.71Å; D103-R125 IonicContact OD1-CZ 3.19Å; D103-R125 IonicContact OD1-NE 2.81Å; D103-R125 PolarHBondContact OD1-NE 3.41Å; D103-R125 IonicContact OD1-NH2 3.74Å; D103-R125 PolarHBondContact OD1-NH2 3.22Å; D103-R125 IonicContact OD2-CZ 3.55Å; D103-R125 IonicContact OD2-NH2 2.7Å; D103-R125 PolarHBondContact OD2-NH2 3.36Å; D103-R125 VanDerWaalsContact OD2-NH2 3.12Å
104	F	65.4	Low	66.3	Low	133 Å²	133	59.5 Å²	59.5	58%	0.583	31%	0.31	S	S	*	.	H	α-helix	trans	-68.5	-38.2	172.2	-77.2	-82.8	0	0	0	112.1	L96 M101 M106 D107 V108	L96-F104 HydrophobicContact CD2-CB 4.09Å; M101-F104 HydrophobicContact CB-CB 4.44Å; M101-F104 HydrophobicContact CB-CD2 4.38Å; M101-F104 PolarHBondContact O-N 3.25Å; M101-F104 HydrophobicContact SD-CD2 4.23Å; F104-M106 VanDerWaalsContact C-N 3.28Å; F104-M106 PolarHBondContact O-N 3.05Å; F104-D107 PolarHBondContact O-N 3.18Å; F104-V108 WeakPolarHBondContact O-CG2 3.17Å; F104-V108 PolarHBondContact O-N 3.37Å
105	A	65.5	Low	65.2	Low	4 Å²	4	60.4 Å²	60.4	3%	0.033	32%	0.315	C	S	.	.	H	α-helix	trans	-59.1	-40.5	173.8	0	0	0	0	0	111.8	L96 M101 V102 Y109 L121	L96-A105 HydrophobicContact CB-CB 3.92Å; M101-A105 PolarHBondContact O-N 3.1Å; V102-A105 PolarHBondContact O-N 3.23Å; A105-Y109 VanDerWaalsContact O-CB 3.26Å; A105-Y109 WeakPolarHBondContact O-CB 3.21Å; A105-Y109 PolarHBondContact O-N 3.01Å; A105-L121 HydrophobicContact CB-CD2 4.48Å
106	M	65	Low	64.1	Low	13 Å²	13	65.5 Å²	65.5	6%	0.064	34%	0.342	C	S	.	.	H	α-helix	trans	-65.7	-39.8	176.7	-75.6	-171.3	-63.3	0	0	112.4	V102 D103 F104 Y109 K110 I117 L121	V102-M106 VanDerWaalsContact O-CG 3.26Å; V102-M106 WeakPolarHBondContact O-CG 3.27Å; V102-M106 PolarHBondContact O-N 3.19Å; D103-M106 HydrophobicContact CB-CE 4.41Å; D103-M106 PolarHBondContact O-N 2.95Å; D103-M106 WeakPolarHBondContact OD1-CE 3.35Å; F104-M106 VanDerWaalsContact C-N 3.28Å; F104-M106 PolarHBondContact O-N 3.05Å; M106-Y109 PolarHBondContact O-N 3.13Å; M106-K110 VanDerWaalsContact O-CG 3.27Å; M106-K110 WeakPolarHBondContact O-CG 3.17Å; M106-K110 PolarHBondContact O-N 3.21Å; M106-I117 HydrophobicContact CG-CD1 4.49Å; M106-I117 HydrophobicContact CG-CG2 3.74Å; M106-I117 HydrophobicContact SD-CD1 3.93Å; M106-I117 HydrophobicContact SD-CG2 3.75Å; M106-L121 HydrophobicContact CG-CB 4.47Å
107	D	69.9	Low	63.4	Low	84 Å²	84	66.8 Å²	66.8	45%	0.449	35%	0.348	S	S	.	.	H	α-helix	trans	-73.7	-38.1	179.8	-71.7	-16.6	0	0	0	112.2	D103 F104 Y109 K110 N111	D103-D107 PolarHBondContact O-N 2.71Å; F104-D107 PolarHBondContact O-N 3.18Å; D107-Y109 VanDerWaalsContact C-N 3.34Å; D107-Y109 PolarHBondContact O-N 2.95Å; D107-K110 PolarHBondContact O-N 3.49Å; D107-K110 IonicContact OD1-NZ 3.53Å; D107-K110 PolarHBondContact OD1-NZ 3.27Å; D107-N111 PolarHBondContact O-N 2.87Å; D107-N111 PolarHBondContact O-ND2 3.46Å; D107-N111 PolarHBondContact O-OD1 2.93Å
108	V	66.1	Low	63.3	Low	20 Å²	20	66.4 Å²	66.4	12%	0.121	35%	0.345	C	S	.	.	H	α-helix	trans	-63.7	-39.7	171.5	172.4	0	0	0	0	111.3	L89 K92 L93 L96 F104 N111 L112	L89-V108 HydrophobicContact CD2-CG1 3.96Å; K92-V108 HydrophobicContact CB-CG1 4.3Å; L93-V108 HydrophobicContact CB-CG1 4.33Å; L96-V108 HydrophobicContact CD1-CB 4.14Å; L96-V108 HydrophobicContact CD1-CG2 3.77Å; F104-V108 WeakPolarHBondContact O-CG2 3.17Å; F104-V108 PolarHBondContact O-N 3.37Å; V108-N111 PolarHBondContact O-N 2.96Å; V108-L112 WeakPolarHBondContact O-CB 3.38Å; V108-L112 PolarHBondContact O-N 3.37Å
109	Y	66.1	Low	63	Low	56 Å²	56	67.6 Å²	67.6	22%	0.22	35%	0.347	C	S	.	.	H	α-helix	trans	-63.9	-43	176.5	-166.2	-82.8	0	0	0	112.1	L93 A105 M106 D107 N111 L112 Y113 P118 L121	L93-Y109 HydrophobicContact CD1-CD2 3.65Å; L93-Y109 HydrophobicContact CD1-CE2 4.33Å; L93-Y109 HydrophobicContact CD1-CG 4.48Å; A105-Y109 VanDerWaalsContact O-CB 3.26Å; A105-Y109 WeakPolarHBondContact O-CB 3.21Å; A105-Y109 PolarHBondContact O-N 3.01Å; M106-Y109 PolarHBondContact O-N 3.13Å; D107-Y109 VanDerWaalsContact C-N 3.34Å; D107-Y109 PolarHBondContact O-N 2.95Å; Y109-N111 VanDerWaalsContact C-N 3.32Å; Y109-N111 PolarHBondContact O-N 3.44Å; Y109-L112 PolarHBondContact O-N 3.5Å; Y109-Y113 HydrophobicContact CD1-CD2 4.46Å; Y109-Y113 HydrophobicContact CD2-CD2 4.3Å; Y109-Y113 HydrophobicContact CE1-CD2 4.05Å; Y109-Y113 AromaticContact CE2-CD2 3.85Å; Y109-Y113 HydrophobicContact CE2-CD2 3.85Å; Y109-Y113 HydrophobicContact CE2-CE2 4.12Å; Y109-Y113 AromaticContact CZ-CD2 3.72Å; Y109-Y113 PolarHBondContact O-N 2.99Å; Y109-P118 HydrophobicContact CD1-CG 4.11Å; Y109-P118 HydrophobicContact CD2-CG 4.2Å; Y109-P118 HydrophobicContact CE1-CG 3.53Å; Y109-P118 HydrophobicContact CE2-CG 3.67Å; Y109-P118 HydrophobicContact CG-CG 4.43Å; Y109-P118 WeakPolarHBondContact OH-CG 3.32Å; Y109-L121 HydrophobicContact CD2-CD1 4.35Å; Y109-L121 HydrophobicContact CG-CD1 4.49Å
110	K	70.3	Confident	63	Low	86 Å²	86	70 Å²	70	37%	0.374	37%	0.368	S	S	.	.	H	α-helix	trans	-61.3	-41	174.5	-74	171.1	-166.7	160.1	0	111.8	M106 D107 L112 S114 I117	M106-K110 VanDerWaalsContact O-CG 3.27Å; M106-K110 WeakPolarHBondContact O-CG 3.17Å; M106-K110 PolarHBondContact O-N 3.21Å; D107-K110 PolarHBondContact O-N 3.49Å; D107-K110 IonicContact OD1-NZ 3.53Å; D107-K110 PolarHBondContact OD1-NZ 3.27Å; K110-L112 VanDerWaalsContact C-N 3.31Å; K110-L112 PolarHBondContact O-N 3.44Å; K110-S114 WeakPolarHBondContact O-CA 3.31Å; K110-S114 PolarHBondContact O-N 3.46Å; K110-I117 HydrophobicContact CG-CG1 4.44Å
111	N	69.4	Low	63.1	Low	117 Å²	117	68.9 Å²	68.9	63%	0.626	36%	0.362	S	S	*	.	H	α-helix	trans	-66.8	-33.9	178	-68.5	-13.4	0	0	0	112.1	D107 V108 Y109	D107-N111 PolarHBondContact O-N 2.87Å; D107-N111 PolarHBondContact O-ND2 3.46Å; D107-N111 PolarHBondContact O-OD1 2.93Å; V108-N111 PolarHBondContact O-N 2.96Å; Y109-N111 VanDerWaalsContact C-N 3.32Å; Y109-N111 PolarHBondContact O-N 3.44Å
112	L	66.3	Low	63.4	Low	29 Å²	29	74.8 Å²	74.8	15%	0.152	38%	0.383	C	S	.	.	H	α-helix	trans	-79.7	-40.9	-177.6	-170.4	72.3	0	0	0	113.4	K86 L89 Q90 L93 V108 Y109 K110	K86-L112 HydrophobicContact CB-CD1 4.32Å; L89-L112 HydrophobicContact CB-CD1 3.68Å; L89-L112 HydrophobicContact CD1-CD1 4.17Å; Q90-L112 HydrophobicContact CG-CD1 4.36Å; Q90-L112 HydrophobicContact CG-CD2 3.73Å; L93-L112 HydrophobicContact CD1-CD2 3.9Å; V108-L112 WeakPolarHBondContact O-CB 3.38Å; V108-L112 PolarHBondContact O-N 3.37Å; Y109-L112 PolarHBondContact O-N 3.5Å; K110-L112 VanDerWaalsContact C-N 3.31Å; K110-L112 PolarHBondContact O-N 3.44Å
113	Y	64.6	Low	64.1	Low	118 Å²	118	79.5 Å²	79.5	46%	0.463	40%	0.404	S	S	.	.	H	α-helix	trans	-114.6	-9.8	-171.9	-69.4	-68.8	0	0	0	115.2	Y109 D115	Y109-Y113 HydrophobicContact CD1-CD2 4.46Å; Y109-Y113 HydrophobicContact CD2-CD2 4.3Å; Y109-Y113 HydrophobicContact CE1-CD2 4.05Å; Y109-Y113 AromaticContact CE2-CD2 3.85Å; Y109-Y113 HydrophobicContact CE2-CD2 3.85Å; Y109-Y113 HydrophobicContact CE2-CE2 4.12Å; Y109-Y113 AromaticContact CZ-CD2 3.72Å; Y109-Y113 PolarHBondContact O-N 2.99Å; Y113-D115 PolarHBondContact O-N 2.89Å
114	S	57.2	Low	64.2	Low	114 Å²	114	80.7 Å²	80.7	80%	0.797	41%	0.406	S	S	*	.			trans	50.2	13.5	-176.7	-76.5	0	0	0	0	115.6	K110	K110-S114 WeakPolarHBondContact O-CA 3.31Å; K110-S114 PolarHBondContact O-N 3.46Å
115	D	49.8	Very low	64.6	Low	126 Å²	126	79.5 Å²	79.5	67%	0.674	40%	0.397	S	S	*	.	S	Bend	trans	-126	160.6	-178.3	-117.2	-17.3	0	0	0	111	Y113	Y113-D115 PolarHBondContact O-N 2.89Å
116	D	49.5	Very low	65.2	Low	143 Å²	143	83.6 Å²	83.6	77%	0.765	42%	0.422	S	S	*	.	P	Polyproline II helix	trans	-53.2	143.5	-164.6	-100.5	-35.3	0	0	0	115.7	P118	D116-P118 WeakPolarHBondContact O-CD 3.23Å
117	I	55	Low	65.9	Low	34 Å²	34	86.2 Å²	86.2	17%	0.174	44%	0.439	C	S	.	.	P	Polyproline II helix	trans	-54.9	124	-178.2	-58.3	159.6	0	0	0	110.7	M106 K110 H119 L121	M106-I117 HydrophobicContact CG-CD1 4.49Å; M106-I117 HydrophobicContact CG-CG2 3.74Å; M106-I117 HydrophobicContact SD-CD1 3.93Å; M106-I117 HydrophobicContact SD-CG2 3.75Å; K110-I117 HydrophobicContact CG-CG1 4.44Å; I117-H119 PolarHBondContact O-N 3.36Å; I117-L121 HydrophobicContact CG2-CB 4.27Å
118	P	59.6	Low	66.3	Low	35 Å²	35	82.8 Å²	82.8	23%	0.227	42%	0.421	C	S	.	.	P	Polyproline II helix	trans	-53.6	134.1	175.7	-28.3	32.9	0	0	0	112.9	Y109 D116 A120 L121 R122	Y109-P118 HydrophobicContact CD1-CG 4.11Å; Y109-P118 HydrophobicContact CD2-CG 4.2Å; Y109-P118 HydrophobicContact CE1-CG 3.53Å; Y109-P118 HydrophobicContact CE2-CG 3.67Å; Y109-P118 HydrophobicContact CG-CG 4.43Å; Y109-P118 WeakPolarHBondContact OH-CG 3.32Å; D116-P118 WeakPolarHBondContact O-CD 3.23Å; P118-A120 PolarHBondContact O-N 3.49Å; P118-A120 VanDerWaalsContact O-N 3.1Å; P118-L121 HydrophobicContact CB-CD1 4.5Å; P118-L121 HydrophobicContact CG-CD1 4.26Å; P118-L121 PolarHBondContact O-N 2.8Å; P118-R122 PolarHBondContact O-N 3.09Å
119	H	60.3	Low	66.8	Low	141 Å²	141	84.8 Å²	84.8	65%	0.653	43%	0.433	S	S	*	.	H	α-helix	trans	-54.7	-32	177.4	-169.8	-84.3	0	0	0	112.6	I117 L121 R122 E123	I117-H119 PolarHBondContact O-N 3.36Å; H119-L121 PolarHBondContact O-N 3.11Å; H119-R122 PolarHBondContact O-N 3.34Å; H119-E123 WeakPolarHBondContact O-CB 3.48Å; H119-E123 PolarHBondContact O-N 2.93Å
120	A	66.2	Low	67.6	Low	63 Å²	63	84.3 Å²	84.3	52%	0.521	44%	0.441	S	S	.	.	H	α-helix	trans	-61.5	-36.9	175.9	0	0	0	0	0	113.5	P118 K124	P118-A120 PolarHBondContact O-N 3.49Å; P118-A120 VanDerWaalsContact O-N 3.1Å; A120-K124 WeakPolarHBondContact O-CB 3.05Å; A120-K124 WeakPolarHBondContact O-CG 3.36Å; A120-K124 PolarHBondContact O-N 3.18Å
121	L	64.9	Low	67.9	Low	24 Å²	24	84.6 Å²	84.6	13%	0.126	44%	0.443	C	S	.	.	H	α-helix	trans	-74.2	-33.1	176.3	-72.6	171	0	0	0	111.4	V102 A105 M106 Y109 I117 P118 H119 R125	V102-L121 HydrophobicContact CG1-CD2 4.37Å; A105-L121 HydrophobicContact CB-CD2 4.48Å; M106-L121 HydrophobicContact CG-CB 4.47Å; Y109-L121 HydrophobicContact CD2-CD1 4.35Å; Y109-L121 HydrophobicContact CG-CD1 4.49Å; I117-L121 HydrophobicContact CG2-CB 4.27Å; P118-L121 HydrophobicContact CB-CD1 4.5Å; P118-L121 HydrophobicContact CG-CD1 4.26Å; P118-L121 PolarHBondContact O-N 2.8Å; H119-L121 PolarHBondContact O-N 3.11Å; L121-R125 WeakPolarHBondContact O-CB 3.36Å; L121-R125 PolarHBondContact O-N 3.23Å
122	R	67.4	Low	68.3	Low	141 Å²	141	81.1 Å²	81.1	53%	0.532	42%	0.424	S	S	.	.	H	α-helix	trans	-68.8	-38.2	175.1	-163.6	179.3	-69.2	-175.9	0.4	111.8	P118 H119 R125 T126	P118-R122 PolarHBondContact O-N 3.09Å; H119-R122 PolarHBondContact O-N 3.34Å; R122-R125 WeakPolarHBondContact O-CB 3.41Å; R122-R125 PolarHBondContact O-N 2.99Å; R122-T126 PolarHBondContact O-N 3.36Å; R122-T126 VanDerWaalsContact O-N 3.1Å; R122-T126 PolarHBondContact O-OG1 3.45Å
123	E	77.6	Confident	68.9	Low	113 Å²	113	86.3 Å²	86.3	53%	0.528	45%	0.446	S	S	.	.	H	α-helix	trans	-68.4	-44.7	174.8	-170.9	173.1	-171.2	0	0	111.8	H119 R125 T126 T127	H119-E123 WeakPolarHBondContact O-CB 3.48Å; H119-E123 PolarHBondContact O-N 2.93Å; E123-R125 VanDerWaalsContact C-N 3.26Å; E123-R125 PolarHBondContact O-N 2.98Å; E123-T126 WeakPolarHBondContact CA-OG1 3.37Å; E123-T126 PolarHBondContact O-N 3.41Å; E123-T126 VanDerWaalsContact O-N 3.11Å; E123-T126 PolarHBondContact O-OG1 3.07Å; E123-T127 PolarHBondContact O-N 2.9Å; E123-T127 PolarHBondContact O-OG1 3.13Å
124	K	72.1	Confident	69.7	Low	101 Å²	101	86.7 Å²	86.7	44%	0.439	45%	0.452	S	S	.	.	H	α-helix	trans	-56.8	-39.4	170.4	-80.1	-173.4	173	-171.1	0	111.9	S97 V102 A120 T126 T127 V128	S97-K124 PolarHBondContact O-NZ 3.4Å; S97-K124 VanDerWaalsContact O-NZ 3.12Å; V102-K124 HydrophobicContact CG1-CB 4.2Å; A120-K124 WeakPolarHBondContact O-CB 3.05Å; A120-K124 WeakPolarHBondContact O-CG 3.36Å; A120-K124 PolarHBondContact O-N 3.18Å; K124-T126 PolarHBondContact O-N 3.16Å; K124-T127 WeakPolarHBondContact CA-OG1 3.43Å; K124-T127 PolarHBondContact O-N 3.49Å; K124-T127 PolarHBondContact O-OG1 3.04Å; K124-V128 WeakPolarHBondContact O-CB 3.22Å; K124-V128 WeakPolarHBondContact O-CG2 3.46Å; K124-V128 PolarHBondContact O-N 3.24Å
125	R	73.3	Confident	70.7	Confident	107 Å²	107	82.7 Å²	82.7	40%	0.404	42%	0.421	S	S	.	.	H	α-helix	trans	-61.7	-45.2	174.9	-167.9	-176	-165.2	-165	2.9	111.8	V102 D103 L121 R122 E123 T127 V128 V129	V102-R125 HydrophobicContact CB-CB 4.33Å; V102-R125 HydrophobicContact CG1-CB 4.28Å; V102-R125 HydrophobicContact CG2-CB 4.47Å; D103-R125 IonicContact OD1-CZ 3.19Å; D103-R125 IonicContact OD1-NE 2.81Å; D103-R125 PolarHBondContact OD1-NE 3.41Å; D103-R125 IonicContact OD1-NH2 3.74Å; D103-R125 PolarHBondContact OD1-NH2 3.22Å; D103-R125 IonicContact OD2-CZ 3.55Å; D103-R125 IonicContact OD2-NH2 2.7Å; D103-R125 PolarHBondContact OD2-NH2 3.36Å; D103-R125 VanDerWaalsContact OD2-NH2 3.12Å; L121-R125 WeakPolarHBondContact O-CB 3.36Å; L121-R125 PolarHBondContact O-N 3.23Å; R122-R125 WeakPolarHBondContact O-CB 3.41Å; R122-R125 PolarHBondContact O-N 2.99Å; E123-R125 VanDerWaalsContact C-N 3.26Å; E123-R125 PolarHBondContact O-N 2.98Å; R125-T127 PolarHBondContact O-N 3.15Å; R125-V128 PolarHBondContact O-N 2.81Å; R125-V129 HydrophobicContact CG-CG2 4.36Å; R125-V129 WeakPolarHBondContact O-CB 3.4Å; R125-V129 WeakPolarHBondContact O-CG2 3.34Å; R125-V129 PolarHBondContact O-N 3.13Å
126	T	78.6	Confident	72	Confident	90 Å²	90	81.2 Å²	81.2	55%	0.552	41%	0.41	S	S	*	.	H	α-helix	trans	-65.3	-37	178.4	41.1	0	0	0	0	112.9	R122 E123 K124 A130	R122-T126 PolarHBondContact O-N 3.36Å; R122-T126 VanDerWaalsContact O-N 3.1Å; R122-T126 PolarHBondContact O-OG1 3.45Å; E123-T126 WeakPolarHBondContact CA-OG1 3.37Å; E123-T126 PolarHBondContact O-N 3.41Å; E123-T126 VanDerWaalsContact O-N 3.11Å; E123-T126 PolarHBondContact O-OG1 3.07Å; K124-T126 PolarHBondContact O-N 3.16Å; T126-A130 VanDerWaalsContact O-CB 3.24Å; T126-A130 WeakPolarHBondContact O-CB 3.4Å; T126-A130 PolarHBondContact O-N 3.13Å
127	T	80.8	Confident	73.4	Confident	68 Å²	68	77.2 Å²	77.2	42%	0.417	40%	0.397	S	S	.	.	H	α-helix	trans	-70.3	-43.9	176.7	54.9	0	0	0	0	111.9	E123 K124 R125 A130 Q131	E123-T127 PolarHBondContact O-N 2.9Å; E123-T127 PolarHBondContact O-OG1 3.13Å; K124-T127 WeakPolarHBondContact CA-OG1 3.43Å; K124-T127 PolarHBondContact O-N 3.49Å; K124-T127 PolarHBondContact O-OG1 3.04Å; R125-T127 PolarHBondContact O-N 3.15Å; T127-A130 PolarHBondContact O-N 2.72Å; T127-Q131 WeakPolarHBondContact O-CG 3.43Å; T127-Q131 PolarHBondContact O-N 3.28Å
128	V	76.5	Confident	74.4	Confident	12 Å²	12	80.9 Å²	80.9	7%	0.073	41%	0.413	C	S	.	.	H	α-helix	trans	-61.7	-45.6	175.4	172.2	0	0	0	0	110.5	N100 V102 K124 R125 A130 Q131 L132 F188	N100-V128 HydrophobicContact CB-CG1 4.08Å; N100-V128 HydrophobicContact CB-CG2 4.13Å; V102-V128 HydrophobicContact CG2-CB 4.34Å; V102-V128 HydrophobicContact CG2-CG1 4.37Å; V102-V128 HydrophobicContact CG2-CG2 4.28Å; K124-V128 WeakPolarHBondContact O-CB 3.22Å; K124-V128 WeakPolarHBondContact O-CG2 3.46Å; K124-V128 PolarHBondContact O-N 3.24Å; R125-V128 PolarHBondContact O-N 2.81Å; V128-A130 VanDerWaalsContact C-N 3.33Å; V128-A130 PolarHBondContact O-N 3.41Å; V128-Q131 PolarHBondContact O-N 3.38Å; V128-L132 WeakPolarHBondContact O-CB 3.19Å; V128-L132 PolarHBondContact O-N 2.98Å; V128-F188 HydrophobicContact CG1-CE1 4.41Å; V128-F188 HydrophobicContact CG1-CZ 3.72Å; V128-F188 VanDerWaalsContact O-CZ 3.29Å; V128-F188 WeakPolarHBondContact O-CZ 3.34Å
129	V	77.9	Confident	74.8	Confident	62 Å²	62	79.3 Å²	79.3	38%	0.376	40%	0.403	S	S	.	.	H	α-helix	trans	-66.6	-34	177.6	172.8	0	0	0	0	112	R125 L132 K133	R125-V129 HydrophobicContact CG-CG2 4.36Å; R125-V129 WeakPolarHBondContact O-CB 3.4Å; R125-V129 WeakPolarHBondContact O-CG2 3.34Å; R125-V129 PolarHBondContact O-N 3.13Å; V129-L132 PolarHBondContact O-N 2.76Å; V129-K133 WeakPolarHBondContact O-CG 3.38Å; V129-K133 PolarHBondContact O-N 3.03Å
130	A	82.5	Confident	75.4	Confident	46 Å²	46	77.2 Å²	77.2	38%	0.38	39%	0.394	S	S	.	.	H	α-helix	trans	-67.1	-43.9	174.8	0	0	0	0	0	111.7	T126 T127 V128 L132 K133 Q134	T126-A130 VanDerWaalsContact O-CB 3.24Å; T126-A130 WeakPolarHBondContact O-CB 3.4Å; T126-A130 PolarHBondContact O-N 3.13Å; T127-A130 PolarHBondContact O-N 2.72Å; V128-A130 VanDerWaalsContact C-N 3.33Å; V128-A130 PolarHBondContact O-N 3.41Å; A130-L132 VanDerWaalsContact C-N 3.34Å; A130-K133 PolarHBondContact O-N 3.44Å; A130-Q134 WeakPolarHBondContact O-CG 3.35Å; A130-Q134 PolarHBondContact O-N 2.86Å
131	Q	76.6	Confident	75.7	Confident	92 Å²	92	77.7 Å²	77.7	43%	0.43	39%	0.391	S	S	.	.	H	α-helix	trans	-62.1	-41.5	173.9	-72.8	176.7	-6.1	0	0	111.3	T127 V128 K133 Q134 L135 F188	T127-Q131 WeakPolarHBondContact O-CG 3.43Å; T127-Q131 PolarHBondContact O-N 3.28Å; V128-Q131 PolarHBondContact O-N 3.38Å; Q131-K133 VanDerWaalsContact C-N 3.34Å; Q131-K133 PolarHBondContact O-N 3.27Å; Q131-Q134 PolarHBondContact O-N 2.82Å; Q131-L135 WeakPolarHBondContact O-CB 3.43Å; Q131-L135 WeakPolarHBondContact O-CD1 3.27Å; Q131-L135 PolarHBondContact O-N 2.95Å; Q131-F188 HydrophobicContact CB-CE2 3.95Å; Q131-F188 HydrophobicContact CB-CZ 3.95Å
132	L	76.8	Confident	75.8	Confident	44 Å²	44	76.9 Å²	76.9	23%	0.23	39%	0.387	C	S	.	.	H	α-helix	trans	-56.4	-49.1	175.1	-162	152.3	0	0	0	110.9	V128 V129 A130 Q136 F188	V128-L132 WeakPolarHBondContact O-CB 3.19Å; V128-L132 PolarHBondContact O-N 2.98Å; V129-L132 PolarHBondContact O-N 2.76Å; A130-L132 VanDerWaalsContact C-N 3.34Å; L132-Q136 WeakPolarHBondContact O-CB 3.4Å; L132-Q136 PolarHBondContact O-N 3.39Å; L132-F188 HydrophobicContact CB-CD1 4.38Å; L132-F188 HydrophobicContact CB-CE1 3.53Å; L132-F188 HydrophobicContact CB-CZ 4.21Å; L132-F188 HydrophobicContact CD1-CE1 3.97Å; L132-F188 HydrophobicContact CG-CD1 4.33Å; L132-F188 HydrophobicContact CG-CE1 3.82Å
133	K	79.3	Confident	75.8	Confident	139 Å²	139	72 Å²	72	60%	0.604	37%	0.373	S	S	*	.	H	α-helix	trans	-65.8	-38.6	-179.4	-73.7	178.7	-179.7	-178.1	0	112.8	V129 A130 Q131 A137	V129-K133 WeakPolarHBondContact O-CG 3.38Å; V129-K133 PolarHBondContact O-N 3.03Å; A130-K133 PolarHBondContact O-N 3.44Å; Q131-K133 VanDerWaalsContact C-N 3.34Å; Q131-K133 PolarHBondContact O-N 3.27Å; K133-A137 WeakPolarHBondContact O-CB 3.43Å; K133-A137 PolarHBondContact O-N 2.78Å
134	Q	81.8	Confident	75.4	Confident	126 Å²	126	72.1 Å²	72.1	59%	0.589	37%	0.372	S	S	*	.	H	α-helix	trans	-65.1	-52.1	176.1	-74.9	176.9	-12.8	0	0	111.2	A130 Q131 Q136 A137 E138	A130-Q134 WeakPolarHBondContact O-CG 3.35Å; A130-Q134 PolarHBondContact O-N 2.86Å; Q131-Q134 PolarHBondContact O-N 2.82Å; Q134-Q136 VanDerWaalsContact C-N 3.3Å; Q134-Q136 PolarHBondContact O-N 3.22Å; Q134-A137 PolarHBondContact O-N 3Å; Q134-A137 VanDerWaalsContact O-N 3.17Å; Q134-E138 WeakPolarHBondContact O-CG 3.25Å; Q134-E138 PolarHBondContact O-N 3.4Å
135	L	78.9	Confident	75	Confident	29 Å²	29	70.9 Å²	70.9	15%	0.152	37%	0.368	C	S	.	.	H	α-helix	trans	-63.4	-36.3	178.4	-77.8	153.1	0	0	0	112	Q131 E138 T139 R184 Y185 F188	Q131-L135 WeakPolarHBondContact O-CB 3.43Å; Q131-L135 WeakPolarHBondContact O-CD1 3.27Å; Q131-L135 PolarHBondContact O-N 2.95Å; L135-E138 PolarHBondContact O-N 3.28Å; L135-T139 VanDerWaalsContact O-CB 3.28Å; L135-T139 WeakPolarHBondContact O-CB 3.41Å; L135-T139 PolarHBondContact O-N 2.99Å; L135-T139 PolarHBondContact O-OG1 3.36Å; L135-R184 HydrophobicContact CD2-CB 4.28Å; L135-Y185 HydrophobicContact CB-CD2 3.97Å; L135-F188 HydrophobicContact CD1-CB 4.2Å; L135-F188 HydrophobicContact CD1-CD1 4.41Å; L135-F188 HydrophobicContact CD1-CD2 4.01Å; L135-F188 HydrophobicContact CD1-CG 3.93Å
136	Q	76.4	Confident	74.4	Confident	96 Å²	96	66.8 Å²	66.8	45%	0.449	35%	0.354	S	S	.	.	H	α-helix	trans	-65	-42.1	175	-173.4	176.2	8.4	0	0	111.2	L132 Q134 T139 E140 Y185	L132-Q136 WeakPolarHBondContact O-CB 3.4Å; L132-Q136 PolarHBondContact O-N 3.39Å; Q134-Q136 VanDerWaalsContact C-N 3.3Å; Q134-Q136 PolarHBondContact O-N 3.22Å; Q136-T139 CarbonylContact O-C 3.55Å; Q136-T139 PolarHBondContact O-N 2.88Å; Q136-E140 WeakPolarHBondContact O-CB 3.26Å; Q136-E140 PolarHBondContact O-N 3.02Å; Q136-Y185 HydrophobicContact CB-CE2 4.28Å
137	A	78.8	Confident	73.6	Confident	58 Å²	58	69.1 Å²	69.1	48%	0.479	36%	0.358	S	S	.	.	H	α-helix	trans	-66.2	-36.2	176.2	0	0	0	0	0	112.5	K133 Q134 T139 P141	K133-A137 WeakPolarHBondContact O-CB 3.43Å; K133-A137 PolarHBondContact O-N 2.78Å; Q134-A137 PolarHBondContact O-N 3Å; Q134-A137 VanDerWaalsContact O-N 3.17Å; A137-T139 VanDerWaalsContact C-N 3.33Å; A137-P141 WeakPolarHBondContact O-CD 3.33Å
138	E	75.9	Confident	72.8	Confident	111 Å²	111	69.7 Å²	69.7	52%	0.519	36%	0.359	S	S	.	.	H	α-helix	trans	-69.7	-30.5	173.9	-70.8	175.6	-173.6	0	0	112.6	Q134 L135 P141 T181	Q134-E138 WeakPolarHBondContact O-CG 3.25Å; Q134-E138 PolarHBondContact O-N 3.4Å; L135-E138 PolarHBondContact O-N 3.28Å; E138-P141 WeakPolarHBondContact O-CD 3.45Å; E138-T181 HydrophobicContact CB-CG2 4.08Å
139	T	69.1	Low	71.9	Confident	2 Å²	2	73.1 Å²	73.1	1%	0.012	38%	0.381	C	S	.	.	H	α-helix	trans	-92.1	-14.7	-178.9	-47.5	0	0	0	0	112.3	L135 Q136 A137 I142 V143 Y185	L135-T139 VanDerWaalsContact O-CB 3.28Å; L135-T139 WeakPolarHBondContact O-CB 3.41Å; L135-T139 PolarHBondContact O-N 2.99Å; L135-T139 PolarHBondContact O-OG1 3.36Å; Q136-T139 CarbonylContact O-C 3.55Å; Q136-T139 PolarHBondContact O-N 2.88Å; A137-T139 VanDerWaalsContact C-N 3.33Å; T139-I142 HydrophobicContact CG2-CB 4.19Å; T139-I142 HydrophobicContact CG2-CD1 4.26Å; T139-I142 CarbonylContact O-C 3.55Å; T139-I142 WeakPolarHBondContact O-CA 3.01Å; T139-I142 VanDerWaalsContact O-CB 3.23Å; T139-I142 WeakPolarHBondContact O-CB 3.4Å; T139-I142 PolarHBondContact O-N 3.41Å; T139-V143 HydrophobicContact CG2-CG2 4.18Å; T139-V143 WeakPolarHBondContact O-CG2 3.41Å; T139-V143 PolarHBondContact O-N 3.38Å; T139-Y185 HydrophobicContact CG2-CD1 3.74Å; T139-Y185 HydrophobicContact CG2-CE1 4.11Å; T139-Y185 HydrophobicContact CG2-CG 4.1Å
140	E	73.1	Confident	70.9	Confident	97 Å²	97	76.3 Å²	76.3	45%	0.453	39%	0.392	S	S	.	.	H	α-helix	trans	-59.2	-42.3	179.8	-162.9	-174	155.9	0	0	113.7	Q136 I142 V143 K144	Q136-E140 WeakPolarHBondContact O-CB 3.26Å; Q136-E140 PolarHBondContact O-N 3.02Å; E140-I142 PolarHBondContact O-N 3.38Å; E140-V143 PolarHBondContact O-N 3.34Å; E140-K144 HydrophobicContact CG-CD 4.45Å; E140-K144 WeakPolarHBondContact O-CB 3.28Å; E140-K144 WeakPolarHBondContact O-CG 3.44Å; E140-K144 PolarHBondContact O-N 3.33Å; E140-K144 IonicContact OE1-NZ 2.67Å; E140-K144 PolarHBondContact OE1-NZ 2.89Å
141	P	71.5	Confident	69.7	Low	73 Å²	73	74.5 Å²	74.5	47%	0.474	38%	0.376	S	S	.	.	H	α-helix	trans	-61.9	-35.7	171.8	-19.3	32.2	0	0	0	111.4	A137 E138 M145	A137-P141 WeakPolarHBondContact O-CD 3.33Å; E138-P141 WeakPolarHBondContact O-CD 3.45Å; P141-M145 WeakPolarHBondContact O-CG 3.08Å; P141-M145 PolarHBondContact O-N 3.32Å
142	I	67.3	Low	68.9	Low	8 Å²	8	72 Å²	72	4%	0.041	37%	0.367	C	S	.	.	H	α-helix	trans	-67.7	-47.5	179.9	-54	175.4	0	0	0	109.8	T139 E140 K144 M145 F146 Y178 T181 L182	T139-I142 HydrophobicContact CG2-CB 4.19Å; T139-I142 HydrophobicContact CG2-CD1 4.26Å; T139-I142 CarbonylContact O-C 3.55Å; T139-I142 WeakPolarHBondContact O-CA 3.01Å; T139-I142 VanDerWaalsContact O-CB 3.23Å; T139-I142 WeakPolarHBondContact O-CB 3.4Å; T139-I142 PolarHBondContact O-N 3.41Å; E140-I142 PolarHBondContact O-N 3.38Å; I142-K144 PolarHBondContact O-N 3.29Å; I142-M145 WeakPolarHBondContact O-CB 3.14Å; I142-M145 PolarHBondContact O-N 3.28Å; I142-M145 VanDerWaalsContact O-N 3.15Å; I142-F146 HydrophobicContact CG2-CD2 3.8Å; I142-F146 HydrophobicContact CG2-CE2 3.36Å; I142-F146 WeakPolarHBondContact O-CD2 3.24Å; I142-F146 PolarHBondContact O-N 3.17Å; I142-Y178 HydrophobicContact CD1-CD1 3.73Å; I142-Y178 HydrophobicContact CD1-CG 4.35Å; I142-Y178 HydrophobicContact CG1-CD1 3.76Å; I142-Y178 HydrophobicContact CG1-CE1 4.47Å; I142-Y178 HydrophobicContact CG1-CG 4.44Å; I142-T181 HydrophobicContact CD1-CG2 4.45Å; I142-L182 HydrophobicContact CG2-CD1 3.85Å
143	V	68.3	Low	68.1	Low	39 Å²	39	79 Å²	79	24%	0.236	39%	0.391	C	S	.	.	H	α-helix	trans	-61.5	-43.5	177.2	176	0	0	0	0	111.4	T139 E140 M145 F146 E147 Y201	T139-V143 HydrophobicContact CG2-CG2 4.18Å; T139-V143 WeakPolarHBondContact O-CG2 3.41Å; T139-V143 PolarHBondContact O-N 3.38Å; E140-V143 PolarHBondContact O-N 3.34Å; V143-M145 PolarHBondContact O-N 3.27Å; V143-F146 CarbonylContact O-C 3.57Å; V143-F146 WeakPolarHBondContact O-CA 3.47Å; V143-F146 PolarHBondContact O-N 2.79Å; V143-E147 HydrophobicContact CG1-CG 4.29Å; V143-E147 PolarHBondContact O-N 2.87Å; V143-Y201 HydrophobicContact CG2-CE1 4.22Å
144	K	68.7	Low	67.1	Low	114 Å²	114	75.4 Å²	75.4	50%	0.496	38%	0.376	S	S	.	.	H	α-helix	trans	-59.4	-30.7	176.2	-79.4	170.5	170.5	160.1	0	113	E140 I142 F146	E140-K144 HydrophobicContact CG-CD 4.45Å; E140-K144 WeakPolarHBondContact O-CB 3.28Å; E140-K144 WeakPolarHBondContact O-CG 3.44Å; E140-K144 PolarHBondContact O-N 3.33Å; E140-K144 IonicContact OE1-NZ 2.67Å; E140-K144 PolarHBondContact OE1-NZ 2.89Å; I142-K144 PolarHBondContact O-N 3.29Å; K144-F146 VanDerWaalsContact C-N 3.34Å
145	M	62.8	Low	65.7	Low	75 Å²	75	70.3 Å²	70.3	37%	0.369	35%	0.352	S	S	.	.	H	α-helix	trans	-77.8	-22.8	177.2	-59.8	-87	-92.3	0	0	112.2	P141 I142 V143 H172	P141-M145 WeakPolarHBondContact O-CG 3.08Å; P141-M145 PolarHBondContact O-N 3.32Å; I142-M145 WeakPolarHBondContact O-CB 3.14Å; I142-M145 PolarHBondContact O-N 3.28Å; I142-M145 VanDerWaalsContact O-N 3.15Å; V143-M145 PolarHBondContact O-N 3.27Å; M145-H172 HydrophobicContact CE-CB 3.39Å; M145-H172 VanDerWaalsContact CE-CG 3.5Å; M145-H172 WeakPolarHBondContact CE-ND1 3.44Å; M145-H172 PolarHBondContact SD-ND1 3.23Å
146	F	60.4	Low	64.7	Low	22 Å²	22	76.1 Å²	76.1	10%	0.096	38%	0.379	C	S	.	.	H	α-helix	trans	-90.1	-24.2	175.4	-72.5	-66	0	0	0	113.7	I142 V143 K144 D148 T152 M155 L168 L182 L208	I142-F146 HydrophobicContact CG2-CD2 3.8Å; I142-F146 HydrophobicContact CG2-CE2 3.36Å; I142-F146 WeakPolarHBondContact O-CD2 3.24Å; I142-F146 PolarHBondContact O-N 3.17Å; V143-F146 CarbonylContact O-C 3.57Å; V143-F146 WeakPolarHBondContact O-CA 3.47Å; V143-F146 PolarHBondContact O-N 2.79Å; K144-F146 VanDerWaalsContact C-N 3.34Å; F146-D148 PolarHBondContact O-N 3.02Å; F146-T152 PolarHBondContact O-OG1 3.36Å; F146-M155 HydrophobicContact CD1-CE 3.73Å; F146-M155 HydrophobicContact CD1-SD 4.05Å; F146-M155 HydrophobicContact CE1-CE 3.45Å; F146-M155 VanDerWaalsContact CE1-CE 3.45Å; F146-M155 HydrophobicContact CE1-SD 4.07Å; F146-L168 HydrophobicContact CE1-CD2 4.41Å; F146-L182 HydrophobicContact CE2-CD1 3.94Å; F146-L208 HydrophobicContact CE1-CD1 3.77Å; F146-L208 HydrophobicContact CZ-CD1 3.66Å
147	E	62.5	Low	63.7	Low	139 Å²	139	75.7 Å²	75.7	65%	0.65	39%	0.386	S	S	*	.	S	Bend	trans	-68	-15.7	173.9	-80.3	-176	163.1	0	0	113.2	V143 P149	V143-E147 HydrophobicContact CG1-CG 4.29Å; V143-E147 PolarHBondContact O-N 2.87Å; E147-P149 VanDerWaalsContact O-CD 3.28Å; E147-P149 WeakPolarHBondContact O-CD 3.34Å
148	D	64	Low	62.3	Low	80 Å²	80	75 Å²	75	43%	0.428	38%	0.376	S	S	.	.			trans	-66	115.8	174.2	-87.3	-26.5	0	0	0	110.9	F146 E150 T151 T152	F146-D148 PolarHBondContact O-N 3.02Å; D148-E150 PolarHBondContact O-N 3.35Å; D148-E150 VanDerWaalsContact O-N 3.17Å; D148-T151 VanDerWaalsContact CB-OG1 3.25Å; D148-T151 WeakPolarHBondContact CB-OG1 3.16Å; D148-T151 PolarHBondContact O-N 2.73Å; D148-T151 PolarHBondContact O-OG1 2.83Å; D148-T151 VanDerWaalsContact O-OG1 3.09Å; D148-T152 PolarHBondContact O-N 2.97Å; D148-T152 PolarHBondContact O-OG1 3.05Å
149	P	57.3	Low	61.3	Low	84 Å²	84	81.4 Å²	81.4	55%	0.545	40%	0.395	S	S	.	.	H	α-helix	trans	-71.6	-14	-169.4	26.5	-34	0	0	0	114.1	E147 R153	E147-P149 VanDerWaalsContact O-CD 3.28Å; E147-P149 WeakPolarHBondContact O-CD 3.34Å; P149-R153 WeakPolarHBondContact O-CB 3.19Å; P149-R153 VanDerWaalsContact O-CG 3.28Å; P149-R153 WeakPolarHBondContact O-CG 3.43Å; P149-R153 PolarHBondContact O-N 3.41Å
150	E	57.7	Low	60.3	Low	128 Å²	128	86.5 Å²	86.5	60%	0.598	42%	0.423	S	S	*	.	H	α-helix	trans	-73.4	-39.8	170.1	-80.7	-160.1	153.8	0	0	111.6	D148 Q154 K171	D148-E150 PolarHBondContact O-N 3.35Å; D148-E150 VanDerWaalsContact O-N 3.17Å; E150-Q154 WeakPolarHBondContact O-CB 3.34Å; E150-Q154 VanDerWaalsContact O-CG 3.31Å; E150-Q154 WeakPolarHBondContact O-CG 3.33Å; E150-Q154 PolarHBondContact O-N 3.28Å; E150-K171 IonicContact OE2-NZ 3.98Å
151	T	57.5	Low	59.4	Low	8 Å²	8	83 Å²	83	5%	0.049	41%	0.412	C	S	.	.	H	α-helix	trans	-70.6	-43.7	-178.9	-10.6	0	0	0	0	110.4	D148 R153 Q154 M155 L168	D148-T151 VanDerWaalsContact CB-OG1 3.25Å; D148-T151 WeakPolarHBondContact CB-OG1 3.16Å; D148-T151 PolarHBondContact O-N 2.73Å; D148-T151 PolarHBondContact O-OG1 2.83Å; D148-T151 VanDerWaalsContact O-OG1 3.09Å; T151-R153 PolarHBondContact O-N 3.25Å; T151-Q154 PolarHBondContact O-N 3.27Å; T151-M155 HydrophobicContact CG2-CE 4.22Å; T151-M155 WeakPolarHBondContact O-CB 3.29Å; T151-M155 WeakPolarHBondContact O-CG 3.43Å; T151-M155 PolarHBondContact O-N 3.33Å; T151-L168 HydrophobicContact CG2-CD1 4.23Å
152	T	59.7	Low	58.7	Low	40 Å²	40	88.8 Å²	88.8	25%	0.245	43%	0.425	C	S	.	.	H	α-helix	trans	-65.1	-37.4	177.5	-5.7	0	0	0	0	112.7	F146 D148 Q156	F146-T152 PolarHBondContact O-OG1 3.36Å; D148-T152 PolarHBondContact O-N 2.97Å; D148-T152 PolarHBondContact O-OG1 3.05Å; T152-Q156 WeakPolarHBondContact O-CG 3.42Å; T152-Q156 PolarHBondContact O-N 2.97Å
153	R	59.5	Low	58.3	Low	192 Å²	192	94.6 Å²	94.6	73%	0.725	45%	0.453	S	S	*	.	H	α-helix	trans	-71.6	-36.8	175.9	-76.5	178.8	179.2	-179.4	1.9	112.4	P149 T151 Q156 S157	P149-R153 WeakPolarHBondContact O-CB 3.19Å; P149-R153 VanDerWaalsContact O-CG 3.28Å; P149-R153 WeakPolarHBondContact O-CG 3.43Å; P149-R153 PolarHBondContact O-N 3.41Å; T151-R153 PolarHBondContact O-N 3.25Å; R153-Q156 PolarHBondContact O-N 2.78Å; R153-S157 PolarHBondContact O-N 3.02Å; R153-S157 VanDerWaalsContact O-N 3.14Å; R153-S157 PolarHBondContact O-OG 2.79Å
154	Q	57.7	Low	57.9	Low	63 Å²	63	92.8 Å²	92.8	29%	0.294	44%	0.443	S	S	.	.	H	α-helix	trans	-72.9	-28.8	175.8	-72.5	-166.1	18.4	0	0	113	E150 T151 Q156 S157 T158 Y167	E150-Q154 WeakPolarHBondContact O-CB 3.34Å; E150-Q154 VanDerWaalsContact O-CG 3.31Å; E150-Q154 WeakPolarHBondContact O-CG 3.33Å; E150-Q154 PolarHBondContact O-N 3.28Å; T151-Q154 PolarHBondContact O-N 3.27Å; Q154-Q156 VanDerWaalsContact C-N 3.32Å; Q154-Q156 PolarHBondContact O-N 3.33Å; Q154-S157 WeakPolarHBondContact CA-OG 3.48Å; Q154-S157 PolarHBondContact O-N 3.37Å; Q154-S157 PolarHBondContact O-OG 3.3Å; Q154-S157 VanDerWaalsContact O-OG 3.07Å; Q154-T158 WeakPolarHBondContact O-CB 3.29Å; Q154-T158 PolarHBondContact O-N 3.3Å; Q154-T158 PolarHBondContact O-OG1 2.85Å; Q154-Y167 VanDerWaalsContact CD-OH 3.31Å; Q154-Y167 PolarHBondContact NE2-OH 3.03Å; Q154-Y167 PolarHBondContact OE1-OH 3.05Å
155	M	53.6	Low	57.4	Low	18 Å²	18	90.2 Å²	90.2	9%	0.089	43%	0.431	C	S	.	.	H	α-helix	trans	-63.1	-35.2	169.2	-75.4	175.1	-176.8	0	0	113.1	F146 T151 L164 L168	F146-M155 HydrophobicContact CD1-CE 3.73Å; F146-M155 HydrophobicContact CD1-SD 4.05Å; F146-M155 HydrophobicContact CE1-CE 3.45Å; F146-M155 VanDerWaalsContact CE1-CE 3.45Å; F146-M155 HydrophobicContact CE1-SD 4.07Å; T151-M155 HydrophobicContact CG2-CE 4.22Å; T151-M155 WeakPolarHBondContact O-CB 3.29Å; T151-M155 WeakPolarHBondContact O-CG 3.43Å; T151-M155 PolarHBondContact O-N 3.33Å; M155-L164 HydrophobicContact CB-CD1 4.37Å; M155-L164 HydrophobicContact CB-CD2 4.42Å; M155-L164 HydrophobicContact CE-CD2 4.43Å; M155-L164 HydrophobicContact CG-CD1 3.82Å; M155-L164 HydrophobicContact CG-CD2 3.68Å; M155-L164 HydrophobicContact CG-CG 4.24Å; M155-L168 HydrophobicContact CE-CD1 3.76Å; M155-L168 HydrophobicContact CE-CD2 3.62Å; M155-L168 HydrophobicContact CE-CG 4.3Å
156	Q	57	Low	57.4	Low	152 Å²	152	91 Å²	91	71%	0.71	44%	0.437	S	S	*	.	H	α-helix	trans	-79.2	-27.8	176.7	-69	176.7	-0.3	0	0	112.7	T152 R153 Q154	T152-Q156 WeakPolarHBondContact O-CG 3.42Å; T152-Q156 PolarHBondContact O-N 2.97Å; R153-Q156 PolarHBondContact O-N 2.78Å; Q154-Q156 VanDerWaalsContact C-N 3.32Å; Q154-Q156 PolarHBondContact O-N 3.33Å
157	S	54.8	Low	57.6	Low	86 Å²	86	92.5 Å²	92.5	60%	0.601	44%	0.442	S	S	*	.	H	α-helix	trans	-83.2	-31.9	179.1	65.2	0	0	0	0	113.7	R153 Q154	R153-S157 PolarHBondContact O-N 3.02Å; R153-S157 VanDerWaalsContact O-N 3.14Å; R153-S157 PolarHBondContact O-OG 2.79Å; Q154-S157 WeakPolarHBondContact CA-OG 3.48Å; Q154-S157 PolarHBondContact O-N 3.37Å; Q154-S157 PolarHBondContact O-OG 3.3Å; Q154-S157 VanDerWaalsContact O-OG 3.07Å
158	T	50.4	Low	57.6	Low	43 Å²	43	86.2 Å²	86.2	26%	0.264	41%	0.413	S	S	.	.			trans	-98	103	-174.9	-54.3	0	0	0	0	109.8	Q154 D160 M163	Q154-T158 WeakPolarHBondContact O-CB 3.29Å; Q154-T158 PolarHBondContact O-N 3.3Å; Q154-T158 PolarHBondContact O-OG1 2.85Å; T158-D160 PolarHBondContact O-N 2.65Å; T158-M163 HydrophobicContact CG2-CB 4.24Å
159	R	53.6	Low	57.5	Low	246 Å²	246	84 Å²	84	93%	0.928	41%	0.406	S	S	*	.			trans	-74	-9.7	178	-83.3	-177.5	167.3	-178.3	-4.4	114.4
160	D	49.2	Very low	57.8	Low	109 Å²	109	86.9 Å²	86.9	58%	0.583	42%	0.417	S	S	*	.			trans	-100.2	107.2	-176.6	-69.6	-39.6	0	0	0	111.7	T158 R162 M163 L164	T158-D160 PolarHBondContact O-N 2.65Å; D160-R162 PolarHBondContact O-N 2.87Å; D160-R162 VanDerWaalsContact O-N 3.12Å; D160-M163 PolarHBondContact O-N 2.7Å; D160-L164 PolarHBondContact O-N 3.42Å
161	G	53.5	Low	57.9	Low	23 Å²	23	86 Å²	86	24%	0.237	41%	0.411	C	S	.	.	H	α-helix	trans	-59.1	-23.8	-176.8	0	0	0	0	0	115.1	F165 V207	G161-F165 WeakPolarHBondContact O-CB 3.47Å; G161-F165 PolarHBondContact O-N 2.91Å; G161-V207 WeakPolarHBondContact CA-O 3.42Å
162	R	56.8	Low	57.7	Low	195 Å²	195	88.6 Å²	88.6	74%	0.736	42%	0.422	S	S	*	.	H	α-helix	trans	-73.4	-46.3	175.5	-96.3	-178.1	179.2	175.9	-0.2	113.4	D160 L164 F165 D166	D160-R162 PolarHBondContact O-N 2.87Å; D160-R162 VanDerWaalsContact O-N 3.12Å; R162-L164 PolarHBondContact O-N 2.85Å; R162-F165 PolarHBondContact O-N 3.46Å; R162-D166 PolarHBondContact O-N 2.81Å
163	M	58.4	Low	57.4	Low	130 Å²	130	89 Å²	89	64%	0.64	43%	0.434	S	S	*	.	H	α-helix	trans	-68.5	-29.3	178.4	-65.5	-152.5	79.3	0	0	111.6	T158 D160 Y167	T158-M163 HydrophobicContact CG2-CB 4.24Å; D160-M163 PolarHBondContact O-N 2.7Å; M163-Y167 WeakPolarHBondContact O-CB 3.46Å; M163-Y167 PolarHBondContact O-N 3Å
164	L	60.8	Low	57.2	Low	2 Å²	2	81.1 Å²	81.1	1%	0.01	41%	0.405	C	S	.	.	H	α-helix	trans	-70.3	-40.4	172.9	-161.7	83.7	0	0	0	111.8	M155 D160 R162 Y167 L168 V207	M155-L164 HydrophobicContact CB-CD1 4.37Å; M155-L164 HydrophobicContact CB-CD2 4.42Å; M155-L164 HydrophobicContact CE-CD2 4.43Å; M155-L164 HydrophobicContact CG-CD1 3.82Å; M155-L164 HydrophobicContact CG-CD2 3.68Å; M155-L164 HydrophobicContact CG-CG 4.24Å; D160-L164 PolarHBondContact O-N 3.42Å; R162-L164 PolarHBondContact O-N 2.85Å; L164-Y167 PolarHBondContact O-N 2.87Å; L164-L168 HydrophobicContact CG-CD1 4.08Å; L164-L168 WeakPolarHBondContact O-CB 3.39Å; L164-L168 WeakPolarHBondContact O-CD1 3.47Å; L164-L168 PolarHBondContact O-N 3.34Å; L164-V207 HydrophobicContact CD2-CG1 3.55Å
165	F	58.2	Low	57.3	Low	59 Å²	59	85.4 Å²	85.4	26%	0.259	42%	0.419	S	S	.	.	H	α-helix	trans	-63.1	-44.9	174.5	-170.9	-90	0	0	0	111.7	G161 R162 L168 A169 F174 L179	G161-F165 WeakPolarHBondContact O-CB 3.47Å; G161-F165 PolarHBondContact O-N 2.91Å; R162-F165 PolarHBondContact O-N 3.46Å; F165-L168 PolarHBondContact O-N 3.12Å; F165-A169 VanDerWaalsContact O-CB 3.29Å; F165-A169 WeakPolarHBondContact O-CB 3.37Å; F165-A169 PolarHBondContact O-N 3.32Å; F165-F174 HydrophobicContact CD2-CD1 4.19Å; F165-F174 HydrophobicContact CD2-CE1 4.44Å; F165-F174 AromaticContact CE2-CD1 3.75Å; F165-F174 HydrophobicContact CE2-CD1 3.75Å; F165-F174 HydrophobicContact CE2-CE1 4.06Å; F165-F174 HydrophobicContact CZ-CD1 4.4Å; F165-L179 HydrophobicContact CE2-CD1 4.19Å
166	D	62.6	Low	57.7	Low	91 Å²	91	91.1 Å²	91.1	49%	0.487	45%	0.445	S	S	.	.	H	α-helix	trans	-65.4	-39.1	176.3	-68.1	-19.5	0	0	0	111.3	R162 L168 A169 D170	R162-D166 PolarHBondContact O-N 2.81Å; D166-L168 PolarHBondContact O-N 3.02Å; D166-A169 PolarHBondContact O-N 2.59Å; D166-D170 VanDerWaalsContact O-CB 3.3Å; D166-D170 WeakPolarHBondContact O-CB 3.41Å; D166-D170 VanDerWaalsContact O-CG 3.28Å; D166-D170 PolarHBondContact O-N 3.43Å
167	Y	64.5	Low	58.3	Low	54 Å²	54	89.8 Å²	89.8	21%	0.212	44%	0.439	C	S	.	.	H	α-helix	trans	-64.7	-37.8	175	-176.9	-103	0	0	0	112.8	Q154 M163 L164 K171	Q154-Y167 VanDerWaalsContact CD-OH 3.31Å; Q154-Y167 PolarHBondContact NE2-OH 3.03Å; Q154-Y167 PolarHBondContact OE1-OH 3.05Å; M163-Y167 WeakPolarHBondContact O-CB 3.46Å; M163-Y167 PolarHBondContact O-N 3Å; L164-Y167 PolarHBondContact O-N 2.87Å; Y167-K171 HydrophobicContact CE1-CD 4.09Å; Y167-K171 HydrophobicContact CE2-CD 3.95Å; Y167-K171 HydrophobicContact CE2-CG 4.25Å; Y167-K171 WeakPolarHBondContact O-CB 3.23Å; Y167-K171 PolarHBondContact O-N 2.93Å; Y167-K171 WeakPolarHBondContact OH-CD 3.45Å; Y167-K171 WeakPolarHBondContact OH-CE 3.21Å; Y167-K171 PolarHBondContact OH-NZ 3.26Å
168	L	62.2	Low	59.1	Low	8 Å²	8	90.4 Å²	90.4	4%	0.042	43%	0.429	C	S	.	.	H	α-helix	trans	-75.2	-32	174.5	-93.6	77	0	0	0	112	F146 T151 M155 L164 F165 D166 H172 G173 F174 L208	F146-L168 HydrophobicContact CE1-CD2 4.41Å; T151-L168 HydrophobicContact CG2-CD1 4.23Å; M155-L168 HydrophobicContact CE-CD1 3.76Å; M155-L168 HydrophobicContact CE-CD2 3.62Å; M155-L168 HydrophobicContact CE-CG 4.3Å; L164-L168 HydrophobicContact CG-CD1 4.08Å; L164-L168 WeakPolarHBondContact O-CB 3.39Å; L164-L168 WeakPolarHBondContact O-CD1 3.47Å; L164-L168 PolarHBondContact O-N 3.34Å; F165-L168 PolarHBondContact O-N 3.12Å; D166-L168 PolarHBondContact O-N 3.02Å; L168-H172 WeakPolarHBondContact O-CA 3.41Å; L168-H172 WeakPolarHBondContact O-CB 3.32Å; L168-H172 PolarHBondContact O-N 3.09Å; L168-G173 PolarHBondContact O-N 2.95Å; L168-F174 HydrophobicContact CB-CB 3.96Å; L168-F174 HydrophobicContact CB-CD2 4.42Å; L168-F174 HydrophobicContact CB-CG 4.17Å; L168-F174 HydrophobicContact CD2-CD2 4.04Å; L168-F174 HydrophobicContact CD2-CE2 4.21Å; L168-F174 HydrophobicContact CD2-CG 4.49Å; L168-F174 WeakPolarHBondContact O-CB 3.25Å; L168-F174 PolarHBondContact O-N 3.32Å; L168-L208 HydrophobicContact CD2-CD2 3.88Å
169	A	62.4	Low	60	Low	32 Å²	32	89 Å²	89	26%	0.264	42%	0.42	S	S	.	.	H	α-helix	trans	-65.7	-45.2	172.6	0	0	0	0	0	111	F165 D166 G173	F165-A169 VanDerWaalsContact O-CB 3.29Å; F165-A169 WeakPolarHBondContact O-CB 3.37Å; F165-A169 PolarHBondContact O-N 3.32Å; D166-A169 PolarHBondContact O-N 2.59Å; A169-G173 WeakPolarHBondContact O-CA 3.42Å; A169-G173 PolarHBondContact O-N 3.08Å
170	D	63.5	Low	61	Low	145 Å²	145	80.2 Å²	80.2	78%	0.775	39%	0.391	S	S	*	.	H	α-helix	trans	-72.6	-39.7	-177.1	-76.1	-14.3	0	0	0	113	D166	D166-D170 VanDerWaalsContact O-CB 3.3Å; D166-D170 WeakPolarHBondContact O-CB 3.41Å; D166-D170 VanDerWaalsContact O-CG 3.28Å; D166-D170 PolarHBondContact O-N 3.43Å
171	K	59.5	Low	62.3	Low	110 Å²	110	76.3 Å²	76.3	48%	0.478	37%	0.371	S	S	.	.	H	α-helix	trans	-84.6	-29.1	-179.9	-78.9	-154.5	169.3	-175.2	0	114.4	E150 Y167	E150-K171 IonicContact OE2-NZ 3.98Å; Y167-K171 HydrophobicContact CE1-CD 4.09Å; Y167-K171 HydrophobicContact CE2-CD 3.95Å; Y167-K171 HydrophobicContact CE2-CG 4.25Å; Y167-K171 WeakPolarHBondContact O-CB 3.23Å; Y167-K171 PolarHBondContact O-N 2.93Å; Y167-K171 WeakPolarHBondContact OH-CD 3.45Å; Y167-K171 WeakPolarHBondContact OH-CE 3.21Å; Y167-K171 PolarHBondContact OH-NZ 3.26Å
172	H	54.5	Low	63.4	Low	63 Å²	63	75.5 Å²	75.5	29%	0.292	36%	0.361	S	S	.	.	H	α-helix	trans	-136.1	-0.7	-163.1	-76.7	-72.6	0	0	0	114.9	M145 L168	M145-H172 HydrophobicContact CE-CB 3.39Å; M145-H172 VanDerWaalsContact CE-CG 3.5Å; M145-H172 WeakPolarHBondContact CE-ND1 3.44Å; M145-H172 PolarHBondContact SD-ND1 3.23Å; L168-H172 WeakPolarHBondContact O-CA 3.41Å; L168-H172 WeakPolarHBondContact O-CB 3.32Å; L168-H172 PolarHBondContact O-N 3.09Å
173	G	52.9	Low	64.4	Low	47 Å²	47	68.2 Å²	68.2	49%	0.485	33%	0.334	S	S	.	.			trans	65.4	40	179.1	0	0	0	0	0	112.6	L168 A169 R175	L168-G173 PolarHBondContact O-N 2.95Å; A169-G173 WeakPolarHBondContact O-CA 3.42Å; A169-G173 PolarHBondContact O-N 3.08Å; G173-R175 PolarHBondContact O-N 3.06Å
174	F	56	Low	65.4	Low	28 Å²	28	69 Å²	69	12%	0.123	33%	0.33	C	S	.	.			trans	-64	128.3	-176.3	-160.4	-96.5	0	0	0	112	F165 L168 L179 L208	F165-F174 HydrophobicContact CD2-CD1 4.19Å; F165-F174 HydrophobicContact CD2-CE1 4.44Å; F165-F174 AromaticContact CE2-CD1 3.75Å; F165-F174 HydrophobicContact CE2-CD1 3.75Å; F165-F174 HydrophobicContact CE2-CE1 4.06Å; F165-F174 HydrophobicContact CZ-CD1 4.4Å; L168-F174 HydrophobicContact CB-CB 3.96Å; L168-F174 HydrophobicContact CB-CD2 4.42Å; L168-F174 HydrophobicContact CB-CG 4.17Å; L168-F174 HydrophobicContact CD2-CD2 4.04Å; L168-F174 HydrophobicContact CD2-CE2 4.21Å; L168-F174 HydrophobicContact CD2-CG 4.49Å; L168-F174 WeakPolarHBondContact O-CB 3.25Å; L168-F174 PolarHBondContact O-N 3.32Å; F174-L179 HydrophobicContact CE1-CD1 3.91Å; F174-L179 HydrophobicContact CE1-CD2 3.91Å; F174-L179 HydrophobicContact CE1-CG 3.62Å; F174-L179 HydrophobicContact CZ-CD2 3.84Å; F174-L179 HydrophobicContact CZ-CG 3.88Å; F174-L208 HydrophobicContact CD1-CD2 4.06Å; F174-L208 HydrophobicContact CE1-CD2 3.4Å; F174-L208 VanDerWaalsContact CE1-CD2 3.4Å; F174-L208 HydrophobicContact CE2-CD2 4.16Å; F174-L208 HydrophobicContact CZ-CD2 3.47Å; F174-L208 VanDerWaalsContact CZ-CD2 3.47Å
175	R	57.9	Low	66.3	Low	152 Å²	152	69.6 Å²	69.6	57%	0.574	33%	0.332	S	S	*	.			trans	-116	149	179.4	-66.9	-174.6	179.4	-173.9	0.1	111	G173 E177 Y178	G173-R175 PolarHBondContact O-N 3.06Å; R175-E177 HydrophobicContact CB-CB 4.36Å; R175-E177 IonicContact NH1-OE2 3.71Å; R175-E177 PolarHBondContact O-N 3.28Å; R175-E177 VanDerWaalsContact O-N 3.1Å; R175-Y178 HydrophobicContact CB-CD2 3.9Å; R175-Y178 HydrophobicContact CB-CE2 4.07Å; R175-Y178 HydrophobicContact CG-CE2 4.4Å; R175-Y178 PolarHBondContact O-N 3.44Å
176	Q	63.5	Low	67.2	Low	139 Å²	139	66.8 Å²	66.8	65%	0.65	32%	0.32	S	S	*	.	H	α-helix	trans	-56.5	-23.9	172.7	-167.9	170.2	8.8	0	0	113	Y178 L179 D180	Q176-Y178 VanDerWaalsContact C-N 3.34Å; Q176-Y178 PolarHBondContact O-N 3.31Å; Q176-L179 WeakPolarHBondContact O-CB 3.38Å; Q176-L179 PolarHBondContact O-N 2.96Å; Q176-D180 PolarHBondContact O-N 2.84Å
177	E	70	Confident	68	Low	123 Å²	123	68 Å²	68	58%	0.575	32%	0.321	S	S	*	.	H	α-helix	trans	-61	-38.2	173.9	-64.2	172	166	0	0	112.4	R175 L179 D180 T181	R175-E177 HydrophobicContact CB-CB 4.36Å; R175-E177 IonicContact NH1-OE2 3.71Å; R175-E177 PolarHBondContact O-N 3.28Å; R175-E177 VanDerWaalsContact O-N 3.1Å; E177-L179 VanDerWaalsContact C-N 3.31Å; E177-L179 PolarHBondContact O-N 3.18Å; E177-D180 PolarHBondContact O-N 3.01Å; E177-T181 PolarHBondContact O-N 2.77Å; E177-T181 PolarHBondContact O-OG1 3.24Å; E177-T181 VanDerWaalsContact O-OG1 3.1Å
178	Y	70.7	Confident	68.8	Low	99 Å²	99	66.1 Å²	66.1	39%	0.388	31%	0.314	S	S	.	.	H	α-helix	trans	-70.3	-28.4	178.2	-64.1	-66.6	0	0	0	112.7	I142 R175 Q176 L182	I142-Y178 HydrophobicContact CD1-CD1 3.73Å; I142-Y178 HydrophobicContact CD1-CG 4.35Å; I142-Y178 HydrophobicContact CG1-CD1 3.76Å; I142-Y178 HydrophobicContact CG1-CE1 4.47Å; I142-Y178 HydrophobicContact CG1-CG 4.44Å; R175-Y178 HydrophobicContact CB-CD2 3.9Å; R175-Y178 HydrophobicContact CB-CE2 4.07Å; R175-Y178 HydrophobicContact CG-CE2 4.4Å; R175-Y178 PolarHBondContact O-N 3.44Å; Q176-Y178 VanDerWaalsContact C-N 3.34Å; Q176-Y178 PolarHBondContact O-N 3.31Å; Y178-L182 WeakPolarHBondContact O-CB 3.22Å; Y178-L182 PolarHBondContact O-N 2.97Å
179	L	69.8	Low	69.4	Low	14 Å²	14	66.4 Å²	66.4	7%	0.073	32%	0.315	C	S	.	.	H	α-helix	trans	-69.2	-39.8	173.9	-71.1	168.8	0	0	0	111.4	F165 F174 Q176 E177 L182 Y183 F205 L208 V209	F165-L179 HydrophobicContact CE2-CD1 4.19Å; F174-L179 HydrophobicContact CE1-CD1 3.91Å; F174-L179 HydrophobicContact CE1-CD2 3.91Å; F174-L179 HydrophobicContact CE1-CG 3.62Å; F174-L179 HydrophobicContact CZ-CD2 3.84Å; F174-L179 HydrophobicContact CZ-CG 3.88Å; Q176-L179 WeakPolarHBondContact O-CB 3.38Å; Q176-L179 PolarHBondContact O-N 2.96Å; E177-L179 VanDerWaalsContact C-N 3.31Å; E177-L179 PolarHBondContact O-N 3.18Å; L179-L182 PolarHBondContact O-N 3.31Å; L179-Y183 WeakPolarHBondContact O-CB 3.3Å; L179-Y183 PolarHBondContact O-N 3.32Å; L179-F205 HydrophobicContact CB-CD2 4.39Å; L179-F205 HydrophobicContact CB-CE2 4Å; L179-F205 HydrophobicContact CD2-CD2 4.01Å; L179-F205 HydrophobicContact CD2-CE2 4.33Å; L179-F205 WeakPolarHBondContact O-CE2 3.2Å; L179-L208 HydrophobicContact CD2-CB 3.92Å; L179-L208 HydrophobicContact CD2-CD2 4.35Å; L179-V209 HydrophobicContact CD1-CG2 4.03Å; L179-V209 HydrophobicContact CD2-CG2 4.11Å
180	D	74.4	Confident	70.1	Confident	61 Å²	61	66.1 Å²	66.1	33%	0.326	31%	0.307	S	S	.	.	H	α-helix	trans	-68.6	-41.2	176.5	-167.4	44.2	0	0	0	111.2	Q176 E177 Y183 R184	Q176-D180 PolarHBondContact O-N 2.84Å; E177-D180 PolarHBondContact O-N 3.01Å; D180-Y183 PolarHBondContact O-N 3.47Å; D180-R184 VanDerWaalsContact O-CG 3.31Å; D180-R184 WeakPolarHBondContact O-CG 3.31Å; D180-R184 PolarHBondContact O-N 3.47Å; D180-R184 IonicContact OD1-NE 3.14Å; D180-R184 IonicContact OD2-CZ 3.69Å; D180-R184 IonicContact OD2-NE 3.04Å; D180-R184 PolarHBondContact OD2-NE 2.93Å; D180-R184 VanDerWaalsContact OD2-NE 3.13Å; D180-R184 IonicContact OD2-NH2 3.03Å; D180-R184 PolarHBondContact OD2-NH2 3.42Å
181	T	76.4	Confident	70.7	Confident	28 Å²	28	61.5 Å²	61.5	17%	0.172	28%	0.281	C	S	.	.	H	α-helix	trans	-62.5	-43.3	173.5	-52.3	0	0	0	0	111.7	E138 I142 E177 Y183 R184 Y185	E138-T181 HydrophobicContact CB-CG2 4.08Å; I142-T181 HydrophobicContact CD1-CG2 4.45Å; E177-T181 PolarHBondContact O-N 2.77Å; E177-T181 PolarHBondContact O-OG1 3.24Å; E177-T181 VanDerWaalsContact O-OG1 3.1Å; T181-Y183 VanDerWaalsContact C-N 3.34Å; T181-Y183 PolarHBondContact O-N 3.45Å; T181-R184 PolarHBondContact O-N 3.3Å; T181-Y185 WeakPolarHBondContact O-CB 3.44Å; T181-Y185 PolarHBondContact O-N 2.74Å
182	L	75.7	Confident	71.2	Confident	5 Å²	5	58.2 Å²	58.2	3%	0.026	27%	0.271	C	S	.	.	H	α-helix	trans	-65.6	-36.5	177	-172.9	139.3	0	0	0	112	I142 F146 Y178 L179 Y185 A186 Y201 F205	I142-L182 HydrophobicContact CG2-CD1 3.85Å; F146-L182 HydrophobicContact CE2-CD1 3.94Å; Y178-L182 WeakPolarHBondContact O-CB 3.22Å; Y178-L182 PolarHBondContact O-N 2.97Å; L179-L182 PolarHBondContact O-N 3.31Å; L182-Y185 PolarHBondContact O-N 3.4Å; L182-A186 VanDerWaalsContact O-CB 3.3Å; L182-A186 WeakPolarHBondContact O-CB 3.33Å; L182-A186 PolarHBondContact O-N 3.4Å; L182-Y201 HydrophobicContact CD1-CD1 4.43Å; L182-Y201 WeakPolarHBondContact CD2-O 3.42Å; L182-F205 HydrophobicContact CD2-CB 3.89Å; L182-F205 HydrophobicContact CD2-CD2 4.23Å
183	Y	78.1	Confident	72	Confident	43 Å²	43	56.4 Å²	56.4	17%	0.169	27%	0.27	C	S	.	.	H	α-helix	trans	-66.3	-43.8	173.5	-178.3	-100.5	0	0	0	112.1	L179 D180 T181 Y185 A186 K187 L202 F205 S218	L179-Y183 WeakPolarHBondContact O-CB 3.3Å; L179-Y183 PolarHBondContact O-N 3.32Å; D180-Y183 PolarHBondContact O-N 3.47Å; T181-Y183 VanDerWaalsContact C-N 3.34Å; T181-Y183 PolarHBondContact O-N 3.45Å; Y183-Y185 VanDerWaalsContact C-N 3.32Å; Y183-Y185 PolarHBondContact O-N 2.78Å; Y183-A186 PolarHBondContact O-N 3.19Å; Y183-K187 WeakPolarHBondContact O-CB 3.21Å; Y183-K187 PolarHBondContact O-N 2.85Å; Y183-L202 HydrophobicContact CD2-CD2 4.44Å; Y183-F205 HydrophobicContact CD2-CE1 4.37Å; Y183-F205 HydrophobicContact CD2-CE2 4.5Å; Y183-F205 HydrophobicContact CD2-CZ 4.26Å; Y183-S218 PolarHBondContact OH-OG 3Å
184	R	79.3	Confident	73.1	Confident	147 Å²	147	57.5 Å²	57.5	56%	0.555	27%	0.265	S	S	*	.	H	α-helix	trans	-62.1	-41.1	174.3	-70.1	175.5	-164.6	-175.4	3.9	111.4	L135 D180 T181 K187 F188	L135-R184 HydrophobicContact CD2-CB 4.28Å; D180-R184 VanDerWaalsContact O-CG 3.31Å; D180-R184 WeakPolarHBondContact O-CG 3.31Å; D180-R184 PolarHBondContact O-N 3.47Å; D180-R184 IonicContact OD1-NE 3.14Å; D180-R184 IonicContact OD2-CZ 3.69Å; D180-R184 IonicContact OD2-NE 3.04Å; D180-R184 PolarHBondContact OD2-NE 2.93Å; D180-R184 VanDerWaalsContact OD2-NE 3.13Å; D180-R184 IonicContact OD2-NH2 3.03Å; D180-R184 PolarHBondContact OD2-NH2 3.42Å; T181-R184 PolarHBondContact O-N 3.3Å; R184-K187 PolarHBondContact O-N 3.48Å; R184-F188 WeakPolarHBondContact O-CB 3.4Å; R184-F188 PolarHBondContact O-N 3.29Å
185	Y	80.3	Confident	74.1	Confident	13 Å²	13	57.8 Å²	57.8	5%	0.051	27%	0.265	C	S	.	.	H	α-helix	trans	-65.1	-44.8	175.5	-175.8	-115.3	0	0	0	111.9	L135 Q136 T139 T181 L182 Y183 K187 F188 Q189 Y201	L135-Y185 HydrophobicContact CB-CD2 3.97Å; Q136-Y185 HydrophobicContact CB-CE2 4.28Å; T139-Y185 HydrophobicContact CG2-CD1 3.74Å; T139-Y185 HydrophobicContact CG2-CE1 4.11Å; T139-Y185 HydrophobicContact CG2-CG 4.1Å; T181-Y185 WeakPolarHBondContact O-CB 3.44Å; T181-Y185 PolarHBondContact O-N 2.74Å; L182-Y185 PolarHBondContact O-N 3.4Å; Y183-Y185 VanDerWaalsContact C-N 3.32Å; Y183-Y185 PolarHBondContact O-N 2.78Å; Y185-K187 VanDerWaalsContact C-N 3.34Å; Y185-K187 PolarHBondContact O-N 3.47Å; Y185-F188 PolarHBondContact O-N 3.03Å; Y185-Q189 HydrophobicContact CD1-CG 4.25Å; Y185-Q189 HydrophobicContact CD2-CG 4.46Å; Y185-Q189 HydrophobicContact CE1-CG 4Å; Y185-Q189 HydrophobicContact CE2-CG 4.22Å; Y185-Q189 WeakPolarHBondContact O-CG 3.34Å; Y185-Q189 PolarHBondContact O-N 3.3Å; Y185-Q189 PolarHBondContact OH-NE2 2.78Å; Y185-Y201 HydrophobicContact CD1-CD2 4.11Å; Y185-Y201 AromaticContact CD1-CE2 3.96Å; Y185-Y201 HydrophobicContact CD1-CE2 3.96Å; Y185-Y201 HydrophobicContact CE1-CD2 4.06Å; Y185-Y201 HydrophobicContact CE1-CE1 4.47Å; Y185-Y201 AromaticContact CE1-CE2 3.45Å; Y185-Y201 HydrophobicContact CE1-CE2 3.45Å; Y185-Y201 VanDerWaalsContact CE1-CE2 3.45Å; Y185-Y201 AromaticContact CE1-CZ 3.69Å
186	A	77.2	Confident	74.9	Confident	1 Å²	1	53.3 Å²	53.3	1%	0.008	26%	0.257	C	S	.	.	H	α-helix	trans	-61.5	-41.9	175.9	0	0	0	0	0	111.9	L182 Y183 F188 Q189 Y190 L202	L182-A186 VanDerWaalsContact O-CB 3.3Å; L182-A186 WeakPolarHBondContact O-CB 3.33Å; L182-A186 PolarHBondContact O-N 3.4Å; Y183-A186 PolarHBondContact O-N 3.19Å; A186-F188 VanDerWaalsContact C-N 3.33Å; A186-F188 PolarHBondContact O-N 3.47Å; A186-Q189 PolarHBondContact O-N 3.44Å; A186-Y190 WeakPolarHBondContact O-CB 3.42Å; A186-Y190 PolarHBondContact O-N 3.24Å; A186-L202 HydrophobicContact CB-CD2 4Å; A186-L202 HydrophobicContact CB-CG 4.12Å
187	K	79.8	Confident	75.4	Confident	117 Å²	117	47.2 Å²	47.2	51%	0.509	23%	0.231	S	C	.	.	H	α-helix	trans	-60.4	-44.2	173.7	-172.2	-174.9	179.5	-159.5	0	111.4	Y183 R184 Y185 Y190 E191	Y183-K187 WeakPolarHBondContact O-CB 3.21Å; Y183-K187 PolarHBondContact O-N 2.85Å; R184-K187 PolarHBondContact O-N 3.48Å; Y185-K187 VanDerWaalsContact C-N 3.34Å; Y185-K187 PolarHBondContact O-N 3.47Å; K187-Y190 PolarHBondContact O-N 3.01Å; K187-E191 WeakPolarHBondContact CE-OE1 3.4Å; K187-E191 IonicContact NZ-OE1 3.46Å; K187-E191 WeakPolarHBondContact O-CG 3.29Å; K187-E191 PolarHBondContact O-N 3.4Å
188	F	80	Confident	75.6	Confident	13 Å²	13	41.3 Å²	41.3	6%	0.057	20%	0.204	C	C	.	.	H	α-helix	trans	-67	-39.5	179.1	-164.3	-91	0	0	0	112.3	V128 Q131 L132 L135 R184 Y185 A186 Y190 E191 C192	V128-F188 HydrophobicContact CG1-CE1 4.41Å; V128-F188 HydrophobicContact CG1-CZ 3.72Å; V128-F188 VanDerWaalsContact O-CZ 3.29Å; V128-F188 WeakPolarHBondContact O-CZ 3.34Å; Q131-F188 HydrophobicContact CB-CE2 3.95Å; Q131-F188 HydrophobicContact CB-CZ 3.95Å; L132-F188 HydrophobicContact CB-CD1 4.38Å; L132-F188 HydrophobicContact CB-CE1 3.53Å; L132-F188 HydrophobicContact CB-CZ 4.21Å; L132-F188 HydrophobicContact CD1-CE1 3.97Å; L132-F188 HydrophobicContact CG-CD1 4.33Å; L132-F188 HydrophobicContact CG-CE1 3.82Å; L135-F188 HydrophobicContact CD1-CB 4.2Å; L135-F188 HydrophobicContact CD1-CD1 4.41Å; L135-F188 HydrophobicContact CD1-CD2 4.01Å; L135-F188 HydrophobicContact CD1-CG 3.93Å; R184-F188 WeakPolarHBondContact O-CB 3.4Å; R184-F188 PolarHBondContact O-N 3.29Å; Y185-F188 PolarHBondContact O-N 3.03Å; A186-F188 VanDerWaalsContact C-N 3.33Å; A186-F188 PolarHBondContact O-N 3.47Å; F188-Y190 VanDerWaalsContact C-N 3.34Å; F188-E191 PolarHBondContact O-N 3.33Å; F188-C192 WeakPolarHBondContact CE1-SG 3Å; F188-C192 WeakPolarHBondContact O-CB 3.44Å; F188-C192 PolarHBondContact O-N 3.43Å; F188-C192 PolarHBondContact O-SG 3.25Å
189	Q	75	Confident	75.8	Confident	15 Å²	15	37.1 Å²	37.1	7%	0.07	19%	0.19	C	C	.	.	H	α-helix	trans	-63.2	-39.9	173.6	-73.3	-69.3	-18	0	0	111.9	Y185 A186 C192 G193 N194 A198	Y185-Q189 HydrophobicContact CD1-CG 4.25Å; Y185-Q189 HydrophobicContact CD2-CG 4.46Å; Y185-Q189 HydrophobicContact CE1-CG 4Å; Y185-Q189 HydrophobicContact CE2-CG 4.22Å; Y185-Q189 WeakPolarHBondContact O-CG 3.34Å; Y185-Q189 PolarHBondContact O-N 3.3Å; Y185-Q189 PolarHBondContact OH-NE2 2.78Å; A186-Q189 PolarHBondContact O-N 3.44Å; Q189-C192 PolarHBondContact O-N 2.63Å; Q189-G193 PolarHBondContact O-N 2.92Å; Q189-G193 VanDerWaalsContact O-N 3.15Å; Q189-N194 PolarHBondContact O-N 3.01Å; Q189-N194 VanDerWaalsContact OE1-CB 3.3Å; Q189-N194 PolarHBondContact OE1-ND2 2.99Å; Q189-A198 HydrophobicContact CB-CB 4.34Å
190	Y	78.6	Confident	75.9	Confident	25 Å²	25	42 Å²	42	10%	0.098	21%	0.212	C	C	.	.	H	α-helix	trans	-63.8	-46.8	174	-178.7	-97.2	0	0	0	111.6	D66 H68 A186 K187 F188 C192 G193 Y195 A225 L229	D66-Y190 PolarHBondContact OD2-OH 3.3Å; H68-Y190 HydrophobicContact CB-CE1 4.45Å; H68-Y190 AromaticContact CD2-CE1 3.7Å; H68-Y190 PolarHBondContact CE1-O 3.05Å; A186-Y190 WeakPolarHBondContact O-CB 3.42Å; A186-Y190 PolarHBondContact O-N 3.24Å; K187-Y190 PolarHBondContact O-N 3.01Å; F188-Y190 VanDerWaalsContact C-N 3.34Å; Y190-C192 PolarHBondContact O-N 2.88Å; Y190-G193 PolarHBondContact O-N 3.5Å; Y190-Y195 AromaticContact CD2-CD1 3.8Å; Y190-Y195 HydrophobicContact CD2-CD1 3.8Å; Y190-Y195 HydrophobicContact CD2-CE1 4.06Å; Y190-Y195 AromaticContact CE2-CD1 4Å; Y190-Y195 HydrophobicContact CE2-CD1 4Å; Y190-Y195 HydrophobicContact CE2-CE1 4.07Å; Y190-A225 HydrophobicContact CE2-CB 3.78Å; Y190-A225 VanDerWaalsContact OH-CB 3.27Å; Y190-A225 WeakPolarHBondContact OH-CB 2.97Å; Y190-L229 HydrophobicContact CE2-CD1 3.83Å
191	E	76.1	Confident	75.9	Confident	49 Å²	49	41.1 Å²	41.1	23%	0.229	21%	0.205	C	C	.	.	H	α-helix	trans	-63.5	-28.7	176.3	-72.8	176.2	-175.1	0	0	113	N100 M101 K187 F188 G193	N100-E191 HydrophobicContact CB-CB 4.24Å; N100-E191 PolarHBondContact ND2-OE2 3.41Å; M101-E191 WeakPolarHBondContact CG-O 3.38Å; K187-E191 WeakPolarHBondContact CE-OE1 3.4Å; K187-E191 IonicContact NZ-OE1 3.46Å; K187-E191 WeakPolarHBondContact O-CG 3.29Å; K187-E191 PolarHBondContact O-N 3.4Å; F188-E191 PolarHBondContact O-N 3.33Å; E191-G193 VanDerWaalsContact C-N 3.34Å
192	C	69.3	Low	75.7	Confident	40 Å²	40	40.2 Å²	40.2	27%	0.27	20%	0.199	S	C	.	.	T	Hydrogen-bonded Turn	trans	-83.4	-6.7	175.1	-66.4	0	0	0	0	113.6	F188 Q189 Y190	F188-C192 WeakPolarHBondContact CE1-SG 3Å; F188-C192 WeakPolarHBondContact O-CB 3.44Å; F188-C192 PolarHBondContact O-N 3.43Å; F188-C192 PolarHBondContact O-SG 3.25Å; Q189-C192 PolarHBondContact O-N 2.63Å; Y190-C192 PolarHBondContact O-N 2.88Å
193	G	70.9	Confident	75.6	Confident	25 Å²	25	44.9 Å²	44.9	26%	0.258	22%	0.217	S	C	.	.	T	Hydrogen-bonded Turn	trans	87.5	13.3	176.8	0	0	0	0	0	115.7	Q189 Y190 E191 Y195	Q189-G193 PolarHBondContact O-N 2.92Å; Q189-G193 VanDerWaalsContact O-N 3.15Å; Y190-G193 PolarHBondContact O-N 3.5Å; E191-G193 VanDerWaalsContact C-N 3.34Å; G193-Y195 WeakPolarHBondContact O-CD2 3.07Å; G193-Y195 WeakPolarHBondContact O-CE2 3.3Å; G193-Y195 PolarHBondContact O-N 3.28Å
194	N	75.9	Confident	75.1	Confident	71 Å²	71	44.8 Å²	44.8	38%	0.38	22%	0.217	S	C	.	.			trans	-94.5	82.3	174.9	-170.2	8	0	0	0	111.1	Q189 S196 A198	Q189-N194 PolarHBondContact O-N 3.01Å; Q189-N194 VanDerWaalsContact OE1-CB 3.3Å; Q189-N194 PolarHBondContact OE1-ND2 2.99Å; N194-S196 PolarHBondContact OD1-OG 3.02Å; N194-A198 WeakPolarHBondContact O-CB 3.27Å; N194-A198 PolarHBondContact O-N 3.25Å
195	Y	76.6	Confident	74.7	Confident	34 Å²	34	38.1 Å²	38.1	13%	0.133	19%	0.192	C	C	.	.	H	α-helix	trans	-75.5	-24.1	-171.5	-46.3	-65.6	0	0	0	114.1	H68 Y190 G193 A199 L229 M230	H68-Y195 AromaticContact ND1-CE1 3.73Å; H68-Y195 AromaticContact ND1-CZ 3.79Å; H68-Y195 PolarHBondContact ND1-OH 2.96Å; Y190-Y195 AromaticContact CD2-CD1 3.8Å; Y190-Y195 HydrophobicContact CD2-CD1 3.8Å; Y190-Y195 HydrophobicContact CD2-CE1 4.06Å; Y190-Y195 AromaticContact CE2-CD1 4Å; Y190-Y195 HydrophobicContact CE2-CD1 4Å; Y190-Y195 HydrophobicContact CE2-CE1 4.07Å; G193-Y195 WeakPolarHBondContact O-CD2 3.07Å; G193-Y195 WeakPolarHBondContact O-CE2 3.3Å; G193-Y195 PolarHBondContact O-N 3.28Å; Y195-A199 VanDerWaalsContact O-CB 3.31Å; Y195-A199 WeakPolarHBondContact O-CB 3.38Å; Y195-A199 PolarHBondContact O-N 3.26Å; Y195-L229 HydrophobicContact CD1-CB 4.23Å; Y195-L229 HydrophobicContact CD1-CD1 3.66Å; Y195-L229 HydrophobicContact CD2-CB 3.83Å; Y195-L229 HydrophobicContact CE1-CB 4.43Å; Y195-L229 HydrophobicContact CE1-CD1 3.35Å; Y195-L229 HydrophobicContact CE1-CG 4.41Å; Y195-L229 HydrophobicContact CE2-CB 4.02Å; Y195-L229 HydrophobicContact CE2-CD1 4.25Å; Y195-L229 HydrophobicContact CG-CB 3.93Å; Y195-L229 HydrophobicContact CG-CD1 4.23Å; Y195-M230 HydrophobicContact CD2-CE 4.39Å
196	S	74.9	Confident	74	Confident	57 Å²	57	41.1 Å²	41.1	40%	0.399	20%	0.204	S	C	.	.	H	α-helix	trans	-73.1	-49	-178.1	45.6	0	0	0	0	110.5	N194 A198 A199 E200	N194-S196 PolarHBondContact OD1-OG 3.02Å; S196-A198 VanDerWaalsContact C-N 3.32Å; S196-A198 PolarHBondContact O-N 2.95Å; S196-A199 PolarHBondContact O-N 2.95Å; S196-E200 PolarHBondContact O-N 3.43Å; S196-E200 VanDerWaalsContact O-N 3.12Å
197	G	74.2	Confident	73.5	Confident	11 Å²	11	42.7 Å²	42.7	11%	0.113	21%	0.213	C	C	.	.	H	α-helix	trans	-59.4	-44.7	172.5	0	0	0	0	0	111.2	A199 E200 Y201	G197-A199 PolarHBondContact O-N 2.94Å; G197-E200 PolarHBondContact O-N 3.09Å; G197-Y201 VanDerWaalsContact C-CD2 3.48Å; G197-Y201 WeakPolarHBondContact O-CD2 3.45Å; G197-Y201 PolarHBondContact O-N 3.14Å
198	A	75.6	Confident	72.7	Confident	0 Å²	0	37.2 Å²	37.2	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-60.8	-41.6	177.6	0	0	0	0	0	112.8	Q189 N194 S196 Y201 L202	Q189-A198 HydrophobicContact CB-CB 4.34Å; N194-A198 WeakPolarHBondContact O-CB 3.27Å; N194-A198 PolarHBondContact O-N 3.25Å; S196-A198 VanDerWaalsContact C-N 3.32Å; S196-A198 PolarHBondContact O-N 2.95Å; A198-Y201 PolarHBondContact O-N 3.4Å; A198-L202 VanDerWaalsContact O-CB 3.3Å; A198-L202 WeakPolarHBondContact O-CB 3.27Å; A198-L202 WeakPolarHBondContact O-CG 3.23Å; A198-L202 PolarHBondContact O-N 3.39Å
199	A	72.9	Confident	71.9	Confident	11 Å²	11	37.3 Å²	37.3	9%	0.091	19%	0.191	C	C	.	.	H	α-helix	trans	-62.7	-42.9	177.4	0	0	0	0	0	112.1	Y195 S196 G197 Y203	Y195-A199 VanDerWaalsContact O-CB 3.31Å; Y195-A199 WeakPolarHBondContact O-CB 3.38Å; Y195-A199 PolarHBondContact O-N 3.26Å; S196-A199 PolarHBondContact O-N 2.95Å; G197-A199 PolarHBondContact O-N 2.94Å; A199-Y203 VanDerWaalsContact O-CB 3.26Å; A199-Y203 WeakPolarHBondContact O-CB 3.27Å; A199-Y203 PolarHBondContact O-N 3.24Å
200	E	73.3	Confident	71.1	Confident	117 Å²	117	38.8 Å²	38.8	55%	0.547	20%	0.202	S	C	.	.	H	α-helix	trans	-65.9	-46.6	175.9	-70.4	-179.1	-178.9	0	0	111.7	S196 G197 L202 Y203 F204	S196-E200 PolarHBondContact O-N 3.43Å; S196-E200 VanDerWaalsContact O-N 3.12Å; G197-E200 PolarHBondContact O-N 3.09Å; E200-L202 VanDerWaalsContact C-N 3.35Å; E200-L202 PolarHBondContact O-N 2.84Å; E200-Y203 WeakPolarHBondContact O-CB 3.26Å; E200-Y203 PolarHBondContact O-N 2.95Å; E200-F204 HydrophobicContact CB-CE2 4.12Å; E200-F204 WeakPolarHBondContact O-CD2 3.4Å; E200-F204 WeakPolarHBondContact O-CG 3.34Å; E200-F204 PolarHBondContact O-N 3.49Å
201	Y	72.9	Confident	69.9	Low	42 Å²	42	42.3 Å²	42.3	17%	0.165	24%	0.236	C	C	.	.	H	α-helix	trans	-62.9	-40.1	177.4	-66	-51.9	0	0	0	112.3	V143 L182 Y185 G197 A198 F204 F205	V143-Y201 HydrophobicContact CG2-CE1 4.22Å; L182-Y201 HydrophobicContact CD1-CD1 4.43Å; L182-Y201 WeakPolarHBondContact CD2-O 3.42Å; Y185-Y201 HydrophobicContact CD1-CD2 4.11Å; Y185-Y201 AromaticContact CD1-CE2 3.96Å; Y185-Y201 HydrophobicContact CD1-CE2 3.96Å; Y185-Y201 HydrophobicContact CE1-CD2 4.06Å; Y185-Y201 HydrophobicContact CE1-CE1 4.47Å; Y185-Y201 AromaticContact CE1-CE2 3.45Å; Y185-Y201 HydrophobicContact CE1-CE2 3.45Å; Y185-Y201 VanDerWaalsContact CE1-CE2 3.45Å; Y185-Y201 AromaticContact CE1-CZ 3.69Å; G197-Y201 VanDerWaalsContact C-CD2 3.48Å; G197-Y201 WeakPolarHBondContact O-CD2 3.45Å; G197-Y201 PolarHBondContact O-N 3.14Å; A198-Y201 PolarHBondContact O-N 3.4Å; Y201-F204 HydrophobicContact CD1-CD2 4.49Å; Y201-F204 PolarHBondContact O-N 3.32Å; Y201-F205 WeakPolarHBondContact O-CB 3.32Å; Y201-F205 PolarHBondContact O-N 3.38Å
202	L	73.7	Confident	68.7	Low	8 Å²	8	45.8 Å²	45.8	4%	0.042	26%	0.261	C	S	.	.	H	α-helix	trans	-71.7	-30.6	175.5	-69	173.7	0	0	0	112.3	Y183 A186 A198 E200 R206 K223	Y183-L202 HydrophobicContact CD2-CD2 4.44Å; A186-L202 HydrophobicContact CB-CD2 4Å; A186-L202 HydrophobicContact CB-CG 4.12Å; A198-L202 VanDerWaalsContact O-CB 3.3Å; A198-L202 WeakPolarHBondContact O-CB 3.27Å; A198-L202 WeakPolarHBondContact O-CG 3.23Å; A198-L202 PolarHBondContact O-N 3.39Å; E200-L202 VanDerWaalsContact C-N 3.35Å; E200-L202 PolarHBondContact O-N 2.84Å; L202-R206 VanDerWaalsContact O-CB 3.29Å; L202-R206 WeakPolarHBondContact O-CB 3.47Å; L202-R206 PolarHBondContact O-N 3.35Å; L202-K223 HydrophobicContact CB-CB 4.23Å; L202-K223 HydrophobicContact CD1-CB 4.45Å
203	Y	73.2	Confident	67.9	Low	103 Å²	103	47.2 Å²	47.2	40%	0.404	27%	0.266	S	S	.	.	H	α-helix	trans	-64	-45.8	169.5	-179.1	-97.6	0	0	0	111	A199 E200 R206 V207	A199-Y203 VanDerWaalsContact O-CB 3.26Å; A199-Y203 WeakPolarHBondContact O-CB 3.27Å; A199-Y203 PolarHBondContact O-N 3.24Å; E200-Y203 WeakPolarHBondContact O-CB 3.26Å; E200-Y203 PolarHBondContact O-N 2.95Å; Y203-R206 WeakPolarHBondContact O-CB 3.26Å; Y203-R206 PolarHBondContact O-N 2.9Å; Y203-V207 HydrophobicContact CD1-CG2 4.37Å; Y203-V207 HydrophobicContact CE1-CG2 3.98Å; Y203-V207 WeakPolarHBondContact O-CG2 3.3Å; Y203-V207 PolarHBondContact O-N 3.33Å
204	F	68.4	Low	67.3	Low	42 Å²	42	57.4 Å²	57.4	18%	0.184	30%	0.296	C	S	.	.	H	α-helix	trans	-63.9	-46.1	175.9	-63.7	-46.9	0	0	0	111.9	E200 Y201 R206 V207 L208	E200-F204 HydrophobicContact CB-CE2 4.12Å; E200-F204 WeakPolarHBondContact O-CD2 3.4Å; E200-F204 WeakPolarHBondContact O-CG 3.34Å; E200-F204 PolarHBondContact O-N 3.49Å; Y201-F204 HydrophobicContact CD1-CD2 4.49Å; Y201-F204 PolarHBondContact O-N 3.32Å; F204-R206 PolarHBondContact O-N 2.85Å; F204-V207 PolarHBondContact O-N 3.11Å; F204-V207 VanDerWaalsContact O-N 3.15Å; F204-L208 WeakPolarHBondContact O-CB 3.38Å; F204-L208 WeakPolarHBondContact O-CD1 3.24Å; F204-L208 PolarHBondContact O-N 2.95Å; F204-L208 VanDerWaalsContact O-N 3.1Å
205	F	69.2	Low	66.6	Low	7 Å²	7	56.8 Å²	56.8	3%	0.031	29%	0.293	C	S	.	.	H	α-helix	trans	-53.7	-40.4	173.8	-174.7	-97.3	0	0	0	111.4	L179 L182 Y183 Y201 L208 V209 N215	L179-F205 HydrophobicContact CB-CD2 4.39Å; L179-F205 HydrophobicContact CB-CE2 4Å; L179-F205 HydrophobicContact CD2-CD2 4.01Å; L179-F205 HydrophobicContact CD2-CE2 4.33Å; L179-F205 WeakPolarHBondContact O-CE2 3.2Å; L182-F205 HydrophobicContact CD2-CB 3.89Å; L182-F205 HydrophobicContact CD2-CD2 4.23Å; Y183-F205 HydrophobicContact CD2-CE1 4.37Å; Y183-F205 HydrophobicContact CD2-CE2 4.5Å; Y183-F205 HydrophobicContact CD2-CZ 4.26Å; Y201-F205 WeakPolarHBondContact O-CB 3.32Å; Y201-F205 PolarHBondContact O-N 3.38Å; F205-L208 PolarHBondContact O-N 2.91Å; F205-V209 HydrophobicContact CD1-CG2 4.12Å; F205-V209 HydrophobicContact CD2-CG2 4.08Å; F205-V209 HydrophobicContact CE1-CB 4.46Å; F205-V209 HydrophobicContact CE1-CG2 3.89Å; F205-V209 HydrophobicContact CE2-CG2 3.84Å; F205-V209 HydrophobicContact CG-CG2 4.22Å; F205-V209 HydrophobicContact CZ-CG2 3.75Å; F205-V209 VanDerWaalsContact O-CB 3.32Å; F205-V209 WeakPolarHBondContact O-CB 3.5Å; F205-V209 WeakPolarHBondContact O-CG2 3.19Å; F205-V209 PolarHBondContact O-N 3.44Å; F205-N215 HydrophobicContact CE1-CB 4.28Å; F205-N215 HydrophobicContact CZ-CB 4.06Å
206	R	65.9	Low	66.1	Low	76 Å²	76	56 Å²	56	29%	0.287	29%	0.294	S	S	.	.	H	α-helix	trans	-67.6	-42	178.1	174.6	-178.9	166.3	-149.6	-15.9	113.7	L202 Y203 F204 L208 D239 R242	L202-R206 VanDerWaalsContact O-CB 3.29Å; L202-R206 WeakPolarHBondContact O-CB 3.47Å; L202-R206 PolarHBondContact O-N 3.35Å; Y203-R206 WeakPolarHBondContact O-CB 3.26Å; Y203-R206 PolarHBondContact O-N 2.9Å; F204-R206 PolarHBondContact O-N 2.85Å; R206-L208 PolarHBondContact O-N 3.45Å; R206-D239 IonicContact NH1-OD1 3.18Å; R206-D239 PolarHBondContact NH1-OD1 3.47Å; R206-R242 VanDerWaalsContact NH2-NE 3.16Å
207	V	67.7	Low	66	Low	33 Å²	33	54.6 Å²	54.6	20%	0.2	28%	0.281	C	S	.	.	H	α-helix	trans	-68.4	-29.4	-180	179.8	0	0	0	0	110.7	G161 L164 Y203 F204	G161-V207 WeakPolarHBondContact CA-O 3.42Å; L164-V207 HydrophobicContact CD2-CG1 3.55Å; Y203-V207 HydrophobicContact CD1-CG2 4.37Å; Y203-V207 HydrophobicContact CE1-CG2 3.98Å; Y203-V207 WeakPolarHBondContact O-CG2 3.3Å; Y203-V207 PolarHBondContact O-N 3.33Å; F204-V207 PolarHBondContact O-N 3.11Å; F204-V207 VanDerWaalsContact O-N 3.15Å
208	L	63.2	Low	66	Low	2 Å²	2	56.6 Å²	56.6	1%	0.01	29%	0.294	C	S	.	.	H	α-helix	trans	-84.9	-30	-178.5	-93.5	133.9	0	0	0	115.1	F146 L168 F174 L179 F204 F205 R206	F146-L208 HydrophobicContact CE1-CD1 3.77Å; F146-L208 HydrophobicContact CZ-CD1 3.66Å; L168-L208 HydrophobicContact CD2-CD2 3.88Å; F174-L208 HydrophobicContact CD1-CD2 4.06Å; F174-L208 HydrophobicContact CE1-CD2 3.4Å; F174-L208 VanDerWaalsContact CE1-CD2 3.4Å; F174-L208 HydrophobicContact CE2-CD2 4.16Å; F174-L208 HydrophobicContact CZ-CD2 3.47Å; F174-L208 VanDerWaalsContact CZ-CD2 3.47Å; L179-L208 HydrophobicContact CD2-CB 3.92Å; L179-L208 HydrophobicContact CD2-CD2 4.35Å; F204-L208 WeakPolarHBondContact O-CB 3.38Å; F204-L208 WeakPolarHBondContact O-CD1 3.24Å; F204-L208 PolarHBondContact O-N 2.95Å; F204-L208 VanDerWaalsContact O-N 3.1Å; F205-L208 PolarHBondContact O-N 2.91Å; R206-L208 PolarHBondContact O-N 3.45Å
209	V	61.6	Low	65.9	Low	16 Å²	16	56.8 Å²	56.8	10%	0.097	30%	0.295	C	S	.	.	S	Bend	trans	-94.5	130.4	-172.9	175.4	0	0	0	0	111	L179 F205 D213	L179-V209 HydrophobicContact CD1-CG2 4.03Å; L179-V209 HydrophobicContact CD2-CG2 4.11Å; F205-V209 HydrophobicContact CD1-CG2 4.12Å; F205-V209 HydrophobicContact CD2-CG2 4.08Å; F205-V209 HydrophobicContact CE1-CB 4.46Å; F205-V209 HydrophobicContact CE1-CG2 3.89Å; F205-V209 HydrophobicContact CE2-CG2 3.84Å; F205-V209 HydrophobicContact CG-CG2 4.22Å; F205-V209 HydrophobicContact CZ-CG2 3.75Å; F205-V209 VanDerWaalsContact O-CB 3.32Å; F205-V209 WeakPolarHBondContact O-CB 3.5Å; F205-V209 WeakPolarHBondContact O-CG2 3.19Å; F205-V209 PolarHBondContact O-N 3.44Å; V209-D213 HydrophobicContact CG1-CB 3.91Å
210	P	58.9	Low	66.1	Low	46 Å²	46	57 Å²	57	30%	0.299	30%	0.295	S	S	.	.			trans	-60.6	144	169.5	-20.6	32.2	0	0	0	111.6	T212 D213	P210-T212 PolarHBondContact O-N 3.27Å; P210-D213 PolarHBondContact O-N 3.25Å
211	A	52.8	Low	66.5	Low	99 Å²	99	52.7 Å²	52.7	82%	0.818	27%	0.273	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.4	6.7	-178.1	0	0	0	0	0	115.9
212	T	51.8	Low	66.9	Low	122 Å²	122	51.5 Å²	51.5	75%	0.748	27%	0.274	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101.7	-9.1	-174.6	50.7	0	0	0	0	114.2	P210	P210-T212 PolarHBondContact O-N 3.27Å
213	D	53.3	Low	67.3	Low	70 Å²	70	51.7 Å²	51.7	37%	0.374	27%	0.274	S	S	.	.	S	Bend	trans	-86.7	145.4	-175.3	-79.4	-15.6	0	0	0	113.6	V209 P210 N215 A216	V209-D213 HydrophobicContact CG1-CB 3.91Å; P210-D213 PolarHBondContact O-N 3.25Å; D213-N215 PolarHBondContact O-N 2.81Å; D213-A216 VanDerWaalsContact O-CB 3.27Å; D213-A216 WeakPolarHBondContact O-CB 3.22Å; D213-A216 PolarHBondContact O-N 3.02Å
214	R	57.5	Low	67.7	Low	238 Å²	238	46.8 Å²	46.8	90%	0.898	26%	0.255	S	S	*	.	H	α-helix	trans	-53.9	-23.9	180	-167.9	161.8	74.7	170.1	3.2	113.8
215	N	61.3	Low	68.3	Low	58 Å²	58	44.8 Å²	44.8	31%	0.31	25%	0.246	S	C	.	.	H	α-helix	trans	-92.3	-6.6	-179	-64.7	-3.6	0	0	0	113.6	F205 D213 S218 S219	F205-N215 HydrophobicContact CE1-CB 4.28Å; F205-N215 HydrophobicContact CZ-CB 4.06Å; D213-N215 PolarHBondContact O-N 2.81Å; N215-S218 PolarHBondContact O-N 3.19Å; N215-S219 WeakPolarHBondContact O-CB 3.49Å; N215-S219 PolarHBondContact O-N 2.86Å; N215-S219 PolarHBondContact O-OG 2.96Å
216	A	64.9	Low	68.8	Low	18 Å²	18	44.4 Å²	44.4	15%	0.149	25%	0.245	C	C	.	.	H	α-helix	trans	-65	-41.3	178.2	0	0	0	0	0	111.7	D213 S219 L220	D213-A216 VanDerWaalsContact O-CB 3.27Å; D213-A216 WeakPolarHBondContact O-CB 3.22Å; D213-A216 PolarHBondContact O-N 3.02Å; A216-S219 WeakPolarHBondContact CA-OG 3.42Å; A216-S219 PolarHBondContact O-OG 3.35Å; A216-L220 WeakPolarHBondContact O-CG 3.4Å; A216-L220 PolarHBondContact O-N 3.24Å; A216-L220 VanDerWaalsContact O-N 3.09Å
217	L	73.3	Confident	69.5	Low	27 Å²	27	42 Å²	42	14%	0.141	24%	0.237	C	C	.	.	H	α-helix	trans	-66.7	-44.6	176.3	-173.4	65.7	0	0	0	111.4	S219 L220 W221 L243 T246 I247	L217-S219 PolarHBondContact O-N 3.5Å; L217-L220 PolarHBondContact O-N 3.45Å; L217-W221 PolarHBondContact O-N 2.92Å; L217-L243 HydrophobicContact CD1-CD1 3.64Å; L217-T246 HydrophobicContact CD1-CG2 4.34Å; L217-I247 HydrophobicContact CD1-CG1 4.02Å
218	S	74.6	Confident	70.1	Confident	53 Å²	53	40.9 Å²	40.9	37%	0.371	23%	0.229	S	C	.	.	H	α-helix	trans	-65.7	-37	-179.6	-163.1	0	0	0	0	112.6	Y183 N215 W221 G222	Y183-S218 PolarHBondContact OH-OG 3Å; N215-S218 PolarHBondContact O-N 3.19Å; S218-W221 PolarHBondContact O-N 3.38Å; S218-G222 PolarHBondContact O-N 3.42Å
219	S	73.8	Confident	70.8	Confident	5 Å²	5	42.3 Å²	42.3	4%	0.035	24%	0.237	C	C	.	.	H	α-helix	trans	-69.2	-35.2	174.6	54.8	0	0	0	0	112.6	N215 A216 L217 G222 K223	N215-S219 WeakPolarHBondContact O-CB 3.49Å; N215-S219 PolarHBondContact O-N 2.86Å; N215-S219 PolarHBondContact O-OG 2.96Å; A216-S219 WeakPolarHBondContact CA-OG 3.42Å; A216-S219 PolarHBondContact O-OG 3.35Å; L217-S219 PolarHBondContact O-N 3.5Å; S219-G222 PolarHBondContact O-N 3.47Å; S219-K223 WeakPolarHBondContact O-CB 3.05Å; S219-K223 PolarHBondContact O-N 3.33Å
220	L	77.2	Confident	71.7	Confident	15 Å²	15	45.8 Å²	45.8	8%	0.079	25%	0.253	C	S	.	.	H	α-helix	trans	-64.1	-42.5	172	-74.8	166.1	0	0	0	112	A216 L217 K223 L224 L243 T246	A216-L220 WeakPolarHBondContact O-CG 3.4Å; A216-L220 PolarHBondContact O-N 3.24Å; A216-L220 VanDerWaalsContact O-N 3.09Å; L217-L220 PolarHBondContact O-N 3.45Å; L220-K223 PolarHBondContact O-N 3.24Å; L220-L224 WeakPolarHBondContact O-CB 3.33Å; L220-L224 PolarHBondContact O-N 3Å; L220-L243 HydrophobicContact CB-CD1 3.95Å; L220-L243 HydrophobicContact CD1-CD1 4.43Å; L220-T246 HydrophobicContact CD1-CG2 4.14Å
221	W	81.9	Confident	72.5	Confident	26 Å²	26	50.4 Å²	50.4	10%	0.098	27%	0.271	C	S	.	.	H	α-helix	trans	-60.9	-48.3	173.9	-75.5	112.8	0	0	0	111.8	L217 S218 K223 L224 A225 L243 I247 W264 L265 W268	L217-W221 PolarHBondContact O-N 2.92Å; S218-W221 PolarHBondContact O-N 3.38Å; W221-K223 VanDerWaalsContact C-N 3.29Å; W221-K223 PolarHBondContact O-N 2.89Å; W221-L224 PolarHBondContact O-N 2.98Å; W221-A225 WeakPolarHBondContact O-CB 3.37Å; W221-A225 PolarHBondContact O-N 2.88Å; W221-L243 HydrophobicContact CD2-CD1 4.4Å; W221-L243 HydrophobicContact CD2-CD2 3.91Å; W221-L243 HydrophobicContact CE3-CD2 3.78Å; W221-L243 HydrophobicContact CH2-CD2 3.85Å; W221-L243 HydrophobicContact CZ2-CD1 4.38Å; W221-L243 HydrophobicContact CZ2-CD2 3.98Å; W221-L243 HydrophobicContact CZ2-CG 4.49Å; W221-L243 HydrophobicContact CZ3-CD2 3.76Å; W221-I247 HydrophobicContact CZ2-CD1 3.97Å; W221-W264 HydrophobicContact CH2-CB 3.83Å; W221-W264 HydrophobicContact CZ2-CB 4.39Å; W221-W264 HydrophobicContact CZ3-CB 4.38Å; W221-L265 HydrophobicContact CH2-CB 4.04Å; W221-L265 HydrophobicContact CH2-CD1 4.16Å; W221-W268 AromaticContact CE3-CD2 3.92Å; W221-W268 HydrophobicContact CE3-CD2 3.92Å; W221-W268 AromaticContact CE3-CE3 3.65Å; W221-W268 HydrophobicContact CE3-CE3 3.65Å; W221-W268 AromaticContact CE3-CH2 3.84Å; W221-W268 HydrophobicContact CE3-CH2 3.84Å; W221-W268 HydrophobicContact CE3-CZ2 4.15Å; W221-W268 AromaticContact CE3-CZ3 3.58Å; W221-W268 HydrophobicContact CE3-CZ3 3.58Å; W221-W268 HydrophobicContact CZ3-CB 4.35Å; W221-W268 AromaticContact CZ3-CD2 3.63Å; W221-W268 HydrophobicContact CZ3-CD2 3.63Å; W221-W268 AromaticContact CZ3-CE3 3.77Å; W221-W268 HydrophobicContact CZ3-CE3 3.77Å; W221-W268 AromaticContact CZ3-CG 3.94Å; W221-W268 HydrophobicContact CZ3-CG 3.94Å; W221-W268 HydrophobicContact CZ3-CH2 4.48Å; W221-W268 HydrophobicContact CZ3-CZ2 4.42Å; W221-W268 HydrophobicContact CZ3-CZ3 4.17Å
222	G	80.3	Confident	73.8	Confident	17 Å²	17	49 Å²	49	18%	0.175	25%	0.25	C	C	.	.	H	α-helix	trans	-62.3	-35.4	177.4	0	0	0	0	0	113.2	S218 S219 S226	S218-G222 PolarHBondContact O-N 3.42Å; S219-G222 PolarHBondContact O-N 3.47Å; G222-S226 WeakPolarHBondContact O-CB 3.5Å; G222-S226 PolarHBondContact O-N 3.44Å; G222-S226 PolarHBondContact O-OG 3.25Å
223	K	81.9	Confident	75	Confident	12 Å²	12	45.8 Å²	45.8	5%	0.052	22%	0.224	C	C	.	.	H	α-helix	trans	-67.4	-49.1	176.7	-171.6	175.2	-167.5	-97.9	0	110.8	L202 S219 L220 W221 A225 S226 E227 D239	L202-K223 HydrophobicContact CB-CB 4.23Å; L202-K223 HydrophobicContact CD1-CB 4.45Å; S219-K223 WeakPolarHBondContact O-CB 3.05Å; S219-K223 PolarHBondContact O-N 3.33Å; L220-K223 PolarHBondContact O-N 3.24Å; W221-K223 VanDerWaalsContact C-N 3.29Å; W221-K223 PolarHBondContact O-N 2.89Å; K223-A225 VanDerWaalsContact C-N 3.31Å; K223-A225 PolarHBondContact O-N 3.39Å; K223-S226 PolarHBondContact O-N 3.4Å; K223-S226 VanDerWaalsContact O-N 3.16Å; K223-E227 WeakPolarHBondContact O-CG 3.36Å; K223-E227 PolarHBondContact O-N 3.15Å; K223-D239 IonicContact NZ-OD1 3.03Å; K223-D239 PolarHBondContact NZ-OD1 3.14Å; K223-D239 IonicContact NZ-OD2 2.87Å; K223-D239 PolarHBondContact NZ-OD2 3.35Å
224	L	81.4	Confident	76.3	Confident	0 Å²	0	47.7 Å²	47.7	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-63.3	-38.9	179.2	-169	144.8	0	0	0	111.2	L220 W221 S226 E227 I228 D239 L240 L243 W268	L220-L224 WeakPolarHBondContact O-CB 3.33Å; L220-L224 PolarHBondContact O-N 3Å; W221-L224 PolarHBondContact O-N 2.98Å; L224-S226 PolarHBondContact O-N 3.01Å; L224-E227 PolarHBondContact O-N 3.25Å; L224-I228 HydrophobicContact CD2-CD1 3.43Å; L224-I228 VanDerWaalsContact CD2-CD1 3.43Å; L224-I228 HydrophobicContact CD2-CG1 4.25Å; L224-I228 HydrophobicContact CG-CD1 4.39Å; L224-I228 VanDerWaalsContact O-CG1 3.29Å; L224-I228 WeakPolarHBondContact O-CG1 3.43Å; L224-I228 PolarHBondContact O-N 3.03Å; L224-D239 HydrophobicContact CD1-CB 4.46Å; L224-L240 HydrophobicContact CD1-CB 3.98Å; L224-L240 HydrophobicContact CD1-CD1 3.98Å; L224-L243 HydrophobicContact CD1-CD2 3.99Å; L224-W268 HydrophobicContact CD2-CB 4.25Å; L224-W268 HydrophobicContact CD2-CD2 4.45Å; L224-W268 HydrophobicContact CD2-CE3 3.46Å; L224-W268 VanDerWaalsContact CD2-CE3 3.46Å; L224-W268 HydrophobicContact CD2-CZ3 4.15Å
225	A	81.4	Confident	77.3	Confident	0 Å²	0	37.6 Å²	37.6	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-60.9	-44.1	173.3	0	0	0	0	0	112.3	Y190 W221 K223 I228 L229 W268	Y190-A225 HydrophobicContact CE2-CB 3.78Å; Y190-A225 VanDerWaalsContact OH-CB 3.27Å; Y190-A225 WeakPolarHBondContact OH-CB 2.97Å; W221-A225 WeakPolarHBondContact O-CB 3.37Å; W221-A225 PolarHBondContact O-N 2.88Å; K223-A225 VanDerWaalsContact C-N 3.31Å; K223-A225 PolarHBondContact O-N 3.39Å; A225-I228 PolarHBondContact O-N 3.13Å; A225-L229 WeakPolarHBondContact O-CD1 3.14Å; A225-L229 VanDerWaalsContact O-CG 3.32Å; A225-L229 WeakPolarHBondContact O-CG 3.33Å; A225-L229 PolarHBondContact O-N 3.36Å; A225-W268 HydrophobicContact CB-CH2 4.08Å; A225-W268 HydrophobicContact CB-CZ3 3.72Å
226	S	80.3	Confident	78.1	Confident	0 Å²	0	34.8 Å²	34.8	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-64.7	-40.6	179.9	-57.8	0	0	0	0	112.2	G222 K223 L224 L229 M230	G222-S226 WeakPolarHBondContact O-CB 3.5Å; G222-S226 PolarHBondContact O-N 3.44Å; G222-S226 PolarHBondContact O-OG 3.25Å; K223-S226 PolarHBondContact O-N 3.4Å; K223-S226 VanDerWaalsContact O-N 3.16Å; L224-S226 PolarHBondContact O-N 3.01Å; S226-L229 PolarHBondContact O-N 3.16Å; S226-M230 PolarHBondContact O-N 3.49Å; S226-M230 VanDerWaalsContact O-N 3.09Å
227	E	79.6	Confident	78.7	Confident	26 Å²	26	35.6 Å²	35.6	12%	0.121	19%	0.187	C	C	.	.	H	α-helix	trans	-69	-38.1	176.8	-69	-72.9	178.9	0	0	112.4	K223 L224 M230 Q231 N232 A236	K223-E227 WeakPolarHBondContact O-CG 3.36Å; K223-E227 PolarHBondContact O-N 3.15Å; L224-E227 PolarHBondContact O-N 3.25Å; E227-M230 PolarHBondContact O-N 3.19Å; E227-Q231 PolarHBondContact O-N 3.49Å; E227-Q231 VanDerWaalsContact O-N 3.16Å; E227-N232 PolarHBondContact O-N 3.2Å; E227-N232 VanDerWaalsContact O-N 3.12Å; E227-N232 WeakPolarHBondContact OE2-CB 3.38Å; E227-N232 PolarHBondContact OE2-ND2 3.47Å; E227-N232 VanDerWaalsContact OE2-ND2 3.11Å; E227-A236 HydrophobicContact CB-CB 4.16Å
228	I	80.1	Confident	79.1	Confident	8 Å²	8	39.4 Å²	39.4	4%	0.041	20%	0.204	C	C	.	.	H	α-helix	trans	-63.2	-43.6	174.6	-69.9	173.2	0	0	0	110.6	L69 L224 A225 M230 Q231 W233 F271 V272	L69-I228 HydrophobicContact CD2-CB 4.08Å; L69-I228 HydrophobicContact CD2-CG2 3.5Å; L224-I228 HydrophobicContact CD2-CD1 3.43Å; L224-I228 VanDerWaalsContact CD2-CD1 3.43Å; L224-I228 HydrophobicContact CD2-CG1 4.25Å; L224-I228 HydrophobicContact CG-CD1 4.39Å; L224-I228 VanDerWaalsContact O-CG1 3.29Å; L224-I228 WeakPolarHBondContact O-CG1 3.43Å; L224-I228 PolarHBondContact O-N 3.03Å; A225-I228 PolarHBondContact O-N 3.13Å; I228-M230 VanDerWaalsContact C-N 3.29Å; I228-M230 PolarHBondContact O-N 3.24Å; I228-Q231 PolarHBondContact O-N 2.94Å; I228-W233 HydrophobicContact CG1-CZ3 4.46Å; I228-W233 HydrophobicContact CG2-CH2 4.28Å; I228-W233 HydrophobicContact CG2-CZ3 4.24Å; I228-F271 HydrophobicContact CD1-CB 4.25Å; I228-F271 HydrophobicContact CG2-CB 4.25Å; I228-F271 HydrophobicContact CG2-CD1 4.24Å; I228-V272 HydrophobicContact CD1-CG2 3.95Å; I228-V272 HydrophobicContact CG1-CG2 3.92Å
229	L	79.4	Confident	79.3	Confident	32 Å²	32	37 Å²	37	17%	0.168	19%	0.187	C	C	.	.	H	α-helix	trans	-68	-30.2	-179.8	-71.1	162.6	0	0	0	112.5	H68 L69 Y190 Y195 A225 S226 Q231	H68-L229 HydrophobicContact CB-CD1 3.72Å; H68-L229 HydrophobicContact CB-CD2 4.45Å; L69-L229 HydrophobicContact CD2-CD1 4.48Å; L69-L229 HydrophobicContact CD2-CD2 3.93Å; L69-L229 HydrophobicContact CD2-CG 3.88Å; Y190-L229 HydrophobicContact CE2-CD1 3.83Å; Y195-L229 HydrophobicContact CD1-CB 4.23Å; Y195-L229 HydrophobicContact CD1-CD1 3.66Å; Y195-L229 HydrophobicContact CD2-CB 3.83Å; Y195-L229 HydrophobicContact CE1-CB 4.43Å; Y195-L229 HydrophobicContact CE1-CD1 3.35Å; Y195-L229 HydrophobicContact CE1-CG 4.41Å; Y195-L229 HydrophobicContact CE2-CB 4.02Å; Y195-L229 HydrophobicContact CE2-CD1 4.25Å; Y195-L229 HydrophobicContact CG-CB 3.93Å; Y195-L229 HydrophobicContact CG-CD1 4.23Å; A225-L229 WeakPolarHBondContact O-CD1 3.14Å; A225-L229 VanDerWaalsContact O-CG 3.32Å; A225-L229 WeakPolarHBondContact O-CG 3.33Å; A225-L229 PolarHBondContact O-N 3.36Å; S226-L229 PolarHBondContact O-N 3.16Å; L229-Q231 VanDerWaalsContact C-N 3.25Å; L229-Q231 PolarHBondContact O-N 3.4Å
230	M	79.2	Confident	79.6	Confident	89 Å²	89	36.9 Å²	36.9	44%	0.438	19%	0.186	S	C	.	.	T	Hydrogen-bonded Turn	trans	-80.1	-2.2	171.5	-75.1	-63.3	-176.6	0	0	114.1	Y195 S226 E227 I228 N232	Y195-M230 HydrophobicContact CD2-CE 4.39Å; S226-M230 PolarHBondContact O-N 3.49Å; S226-M230 VanDerWaalsContact O-N 3.09Å; E227-M230 PolarHBondContact O-N 3.19Å; I228-M230 VanDerWaalsContact C-N 3.29Å; I228-M230 PolarHBondContact O-N 3.24Å; M230-N232 PolarHBondContact O-N 3.02Å
231	Q	77	Confident	79.9	Confident	143 Å²	143	39 Å²	39	67%	0.668	20%	0.2	S	C	*	.	T	Hydrogen-bonded Turn	trans	59.5	28.7	-179	-52.8	-179.1	-0.8	0	0	114	E227 I228 L229 W233	E227-Q231 PolarHBondContact O-N 3.49Å; E227-Q231 VanDerWaalsContact O-N 3.16Å; I228-Q231 PolarHBondContact O-N 2.94Å; L229-Q231 VanDerWaalsContact C-N 3.25Å; L229-Q231 PolarHBondContact O-N 3.4Å; Q231-W233 HydrophobicContact CB-CZ2 3.96Å; Q231-W233 HydrophobicContact CG-CZ2 4.22Å; Q231-W233 VanDerWaalsContact O-CD1 3.26Å; Q231-W233 PolarHBondContact O-N 3.07Å; Q231-W233 PolarHBondContact O-NE1 3.45Å; Q231-W233 VanDerWaalsContact O-NE1 3.15Å
232	N	79.4	Confident	79.7	Confident	70 Å²	70	41.4 Å²	41.4	37%	0.374	21%	0.209	S	C	.	.			trans	-95.5	86	-179.7	-171.4	14.9	0	0	0	110.9	E227 M230 D234 A235 A236	E227-N232 PolarHBondContact O-N 3.2Å; E227-N232 VanDerWaalsContact O-N 3.12Å; E227-N232 WeakPolarHBondContact OE2-CB 3.38Å; E227-N232 PolarHBondContact OE2-ND2 3.47Å; E227-N232 VanDerWaalsContact OE2-ND2 3.11Å; M230-N232 PolarHBondContact O-N 3.02Å; N232-D234 PolarHBondContact O-N 3.29Å; N232-A235 WeakPolarHBondContact ND2-CB 3.06Å; N232-A236 VanDerWaalsContact O-CB 3.31Å; N232-A236 WeakPolarHBondContact O-CB 3.49Å; N232-A236 PolarHBondContact O-N 2.76Å; N232-A236 VanDerWaalsContact O-N 3.13Å
233	W	77.2	Confident	79.8	Confident	55 Å²	55	40.6 Å²	40.6	21%	0.208	20%	0.201	C	C	.	.	H	α-helix	trans	-72.6	-28.4	-167.9	-51.2	109.3	0	0	0	114.7	I228 Q231 M237 F271 N275	I228-W233 HydrophobicContact CG1-CZ3 4.46Å; I228-W233 HydrophobicContact CG2-CH2 4.28Å; I228-W233 HydrophobicContact CG2-CZ3 4.24Å; Q231-W233 HydrophobicContact CB-CZ2 3.96Å; Q231-W233 HydrophobicContact CG-CZ2 4.22Å; Q231-W233 VanDerWaalsContact O-CD1 3.26Å; Q231-W233 PolarHBondContact O-N 3.07Å; Q231-W233 PolarHBondContact O-NE1 3.45Å; Q231-W233 VanDerWaalsContact O-NE1 3.15Å; W233-M237 WeakPolarHBondContact O-CB 3.42Å; W233-M237 PolarHBondContact O-N 3.31Å; W233-F271 VanDerWaalsContact CZ3-O 3.32Å; W233-F271 WeakPolarHBondContact CZ3-O 3.48Å; W233-N275 HydrophobicContact CD2-CB 3.51Å; W233-N275 VanDerWaalsContact CE2-CB 3.43Å; W233-N275 HydrophobicContact CE3-CB 3.94Å; W233-N275 HydrophobicContact CG-CB 3.94Å; W233-N275 HydrophobicContact CH2-CB 4.24Å; W233-N275 WeakPolarHBondContact CH2-ND2 3.48Å; W233-N275 HydrophobicContact CZ2-CB 3.84Å; W233-N275 WeakPolarHBondContact CZ2-ND2 3.42Å; W233-N275 HydrophobicContact CZ3-CB 4.27Å
234	D	80.1	Confident	79.7	Confident	110 Å²	110	42.2 Å²	42.2	59%	0.588	21%	0.208	S	C	*	.	H	α-helix	trans	-71.1	-46	-179.7	-69.7	-37.2	0	0	0	111.5	N232 M237 E238 H276	N232-D234 PolarHBondContact O-N 3.29Å; D234-M237 WeakPolarHBondContact O-CB 3.4Å; D234-M237 PolarHBondContact O-N 2.83Å; D234-E238 PolarHBondContact O-N 2.94Å; D234-H276 IonicContact OD1-CD2 3.53Å; D234-H276 PolarHBondContact OD1-CD2 3.08Å; D234-H276 IonicContact OD1-NE2 3.55Å; D234-H276 PolarHBondContact OD1-NE2 3.46Å
235	A	78.1	Confident	79.7	Confident	25 Å²	25	47.8 Å²	47.8	21%	0.207	23%	0.234	C	C	.	.	H	α-helix	trans	-67.1	-40.3	174.9	0	0	0	0	0	111.4	N232 M237 E238 D239	N232-A235 WeakPolarHBondContact ND2-CB 3.06Å; A235-M237 PolarHBondContact O-N 3.46Å; A235-E238 PolarHBondContact O-N 2.9Å; A235-D239 PolarHBondContact O-N 3.3Å
236	A	79.1	Confident	79.6	Confident	0 Å²	0	50.3 Å²	50.3	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-60.3	-33.6	175.8	0	0	0	0	0	112.5	E227 N232 D239 L240 V272	E227-A236 HydrophobicContact CB-CB 4.16Å; N232-A236 VanDerWaalsContact O-CB 3.31Å; N232-A236 WeakPolarHBondContact O-CB 3.49Å; N232-A236 PolarHBondContact O-N 2.76Å; N232-A236 VanDerWaalsContact O-N 3.13Å; A236-D239 PolarHBondContact O-N 2.9Å; A236-L240 VanDerWaalsContact O-CB 3.24Å; A236-L240 WeakPolarHBondContact O-CB 2.98Å; A236-L240 PolarHBondContact O-N 3.04Å; A236-V272 HydrophobicContact CB-CG1 4.06Å; A236-V272 HydrophobicContact CB-CG2 3.97Å
237	M	77.6	Confident	79.4	Confident	34 Å²	34	50.4 Å²	50.4	17%	0.167	25%	0.25	C	S	.	.	H	α-helix	trans	-66	-42.4	176.1	-175.3	67.5	-160	0	0	112.3	W233 D234 A235 L240 T241 V272 F273 N282	W233-M237 WeakPolarHBondContact O-CB 3.42Å; W233-M237 PolarHBondContact O-N 3.31Å; D234-M237 WeakPolarHBondContact O-CB 3.4Å; D234-M237 PolarHBondContact O-N 2.83Å; A235-M237 PolarHBondContact O-N 3.46Å; M237-L240 PolarHBondContact O-N 3.4Å; M237-T241 HydrophobicContact CE-CG2 4.02Å; M237-T241 WeakPolarHBondContact O-CG2 3.43Å; M237-T241 PolarHBondContact O-N 3.48Å; M237-T241 VanDerWaalsContact O-N 3.1Å; M237-T241 PolarHBondContact O-OG1 3.47Å; M237-V272 HydrophobicContact CB-CG1 4.48Å; M237-F273 HydrophobicContact CE-CE1 3.8Å; M237-F273 HydrophobicContact SD-CD1 4.07Å; M237-F273 HydrophobicContact SD-CE1 3.54Å; M237-F273 VanDerWaalsContact SD-CE1 3.54Å; M237-N282 HydrophobicContact CE-CB 4.21Å; M237-N282 WeakPolarHBondContact CE-ND2 3.48Å
238	E	80.6	Confident	79.2	Confident	107 Å²	107	51.5 Å²	51.5	50%	0.5	26%	0.257	S	S	.	.	H	α-helix	trans	-64.6	-41.4	173.5	-72.9	-165.2	-171	0	0	112	D234 A235 L240 T241 R242	D234-E238 PolarHBondContact O-N 2.94Å; A235-E238 PolarHBondContact O-N 2.9Å; E238-L240 VanDerWaalsContact C-N 3.31Å; E238-T241 PolarHBondContact O-OG1 2.68Å; E238-R242 VanDerWaalsContact O-CG 3.31Å; E238-R242 WeakPolarHBondContact O-CG 3.26Å; E238-R242 PolarHBondContact O-N 3.28Å; E238-R242 IonicContact OE2-CZ 2.7Å; E238-R242 IonicContact OE2-NH1 3.4Å; E238-R242 IonicContact OE2-NH2 3.7Å; E238-R242 PolarHBondContact OE2-NH2 2.83Å
239	D	79.5	Confident	79.1	Confident	2 Å²	2	57.3 Å²	57.3	1%	0.011	29%	0.288	C	S	.	.	H	α-helix	trans	-69.3	-32.7	178.7	-71.9	-29	0	0	0	111.8	R206 K223 L224 A235 A236 R242 L243	R206-D239 IonicContact NH1-OD1 3.18Å; R206-D239 PolarHBondContact NH1-OD1 3.47Å; K223-D239 IonicContact NZ-OD1 3.03Å; K223-D239 PolarHBondContact NZ-OD1 3.14Å; K223-D239 IonicContact NZ-OD2 2.87Å; K223-D239 PolarHBondContact NZ-OD2 3.35Å; L224-D239 HydrophobicContact CD1-CB 4.46Å; A235-D239 PolarHBondContact O-N 3.3Å; A236-D239 PolarHBondContact O-N 2.9Å; D239-R242 PolarHBondContact O-N 2.87Å; D239-R242 IonicContact OD1-NH1 2.74Å; D239-L243 WeakPolarHBondContact O-CB 3.01Å; D239-L243 PolarHBondContact O-N 3.41Å
240	L	81.3	Confident	78.7	Confident	3 Å²	3	58.5 Å²	58.5	2%	0.016	29%	0.294	C	S	.	.	H	α-helix	trans	-65.7	-45.6	175.3	-176.9	71.5	0	0	0	112.1	L224 A236 M237 E238 R242 L243 K244 L265 F273	L224-L240 HydrophobicContact CD1-CB 3.98Å; L224-L240 HydrophobicContact CD1-CD1 3.98Å; A236-L240 VanDerWaalsContact O-CB 3.24Å; A236-L240 WeakPolarHBondContact O-CB 2.98Å; A236-L240 PolarHBondContact O-N 3.04Å; M237-L240 PolarHBondContact O-N 3.4Å; E238-L240 VanDerWaalsContact C-N 3.31Å; L240-R242 VanDerWaalsContact C-N 3.29Å; L240-R242 PolarHBondContact O-N 3.19Å; L240-L243 PolarHBondContact O-N 2.89Å; L240-K244 WeakPolarHBondContact O-CB 3.49Å; L240-K244 PolarHBondContact O-N 3.49Å; L240-L265 HydrophobicContact CD1-CD1 3.54Å; L240-L265 HydrophobicContact CD1-CG 4.26Å; L240-F273 HydrophobicContact CD2-CD1 4.43Å; L240-F273 HydrophobicContact CD2-CE1 3.72Å; L240-F273 HydrophobicContact CD2-CE2 3.83Å; L240-F273 HydrophobicContact CD2-CZ 3.38Å
241	T	82.3	Confident	77.9	Confident	61 Å²	61	59.7 Å²	59.7	37%	0.374	31%	0.312	S	S	.	.	H	α-helix	trans	-62.4	-38.9	177.7	50.6	0	0	0	0	111.7	M237 E238 K244 E245	M237-T241 HydrophobicContact CE-CG2 4.02Å; M237-T241 WeakPolarHBondContact O-CG2 3.43Å; M237-T241 PolarHBondContact O-N 3.48Å; M237-T241 VanDerWaalsContact O-N 3.1Å; M237-T241 PolarHBondContact O-OG1 3.47Å; E238-T241 PolarHBondContact O-OG1 2.68Å; T241-K244 WeakPolarHBondContact O-CB 3.42Å; T241-K244 PolarHBondContact O-N 3.11Å; T241-E245 WeakPolarHBondContact O-CG 3.44Å; T241-E245 PolarHBondContact O-N 2.79Å
242	R	78.1	Confident	77.1	Confident	76 Å²	76	59.1 Å²	59.1	29%	0.287	32%	0.318	S	S	.	.	H	α-helix	trans	-70.9	-38.9	176	-67.9	176.3	-174.9	136.5	7.4	113.1	R206 E238 D239 L240 K244 E245 T246	R206-R242 VanDerWaalsContact NH2-NE 3.16Å; E238-R242 VanDerWaalsContact O-CG 3.31Å; E238-R242 WeakPolarHBondContact O-CG 3.26Å; E238-R242 PolarHBondContact O-N 3.28Å; E238-R242 IonicContact OE2-CZ 2.7Å; E238-R242 IonicContact OE2-NH1 3.4Å; E238-R242 IonicContact OE2-NH2 3.7Å; E238-R242 PolarHBondContact OE2-NH2 2.83Å; D239-R242 PolarHBondContact O-N 2.87Å; D239-R242 IonicContact OD1-NH1 2.74Å; L240-R242 VanDerWaalsContact C-N 3.29Å; L240-R242 PolarHBondContact O-N 3.19Å; R242-K244 VanDerWaalsContact C-N 3.29Å; R242-K244 PolarHBondContact O-N 2.83Å; R242-E245 PolarHBondContact O-N 2.88Å; R242-T246 WeakPolarHBondContact O-CB 3.09Å; R242-T246 PolarHBondContact O-N 2.9Å; R242-T246 PolarHBondContact O-OG1 3.09Å
243	L	81.7	Confident	76.3	Confident	0 Å²	0	57 Å²	57	0%	0	31%	0.308	C	S	.	.	H	α-helix	trans	-62.3	-41.5	174.5	-179.2	59.1	0	0	0	110.4	L217 L220 W221 L224 D239 L240 T246 I247 L265	L217-L243 HydrophobicContact CD1-CD1 3.64Å; L220-L243 HydrophobicContact CB-CD1 3.95Å; L220-L243 HydrophobicContact CD1-CD1 4.43Å; W221-L243 HydrophobicContact CD2-CD1 4.4Å; W221-L243 HydrophobicContact CD2-CD2 3.91Å; W221-L243 HydrophobicContact CE3-CD2 3.78Å; W221-L243 HydrophobicContact CH2-CD2 3.85Å; W221-L243 HydrophobicContact CZ2-CD1 4.38Å; W221-L243 HydrophobicContact CZ2-CD2 3.98Å; W221-L243 HydrophobicContact CZ2-CG 4.49Å; W221-L243 HydrophobicContact CZ3-CD2 3.76Å; L224-L243 HydrophobicContact CD1-CD2 3.99Å; D239-L243 WeakPolarHBondContact O-CB 3.01Å; D239-L243 PolarHBondContact O-N 3.41Å; L240-L243 PolarHBondContact O-N 2.89Å; L243-T246 PolarHBondContact O-N 3.46Å; L243-I247 HydrophobicContact CD1-CD1 3.92Å; L243-I247 HydrophobicContact CD1-CG1 4.3Å; L243-I247 HydrophobicContact CG-CD1 3.86Å; L243-I247 VanDerWaalsContact O-CG1 3.28Å; L243-I247 WeakPolarHBondContact O-CG1 3.24Å; L243-I247 PolarHBondContact O-N 3.43Å; L243-L265 HydrophobicContact CB-CD1 4.33Å; L243-L265 HydrophobicContact CD2-CD1 3.45Å; L243-L265 VanDerWaalsContact CD2-CD1 3.45Å; L243-L265 HydrophobicContact CG-CD1 3.76Å
244	K	79.4	Confident	76.4	Confident	45 Å²	45	56.7 Å²	56.7	20%	0.196	31%	0.314	C	S	.	.	H	α-helix	trans	-57.8	-52.2	172.6	-173.6	-161.2	-178.3	176.9	0	111.8	L240 T241 R242 T246 I247 D248 L265 L286	L240-K244 WeakPolarHBondContact O-CB 3.49Å; L240-K244 PolarHBondContact O-N 3.49Å; T241-K244 WeakPolarHBondContact O-CB 3.42Å; T241-K244 PolarHBondContact O-N 3.11Å; R242-K244 VanDerWaalsContact C-N 3.29Å; R242-K244 PolarHBondContact O-N 2.83Å; K244-T246 VanDerWaalsContact C-N 3.26Å; K244-T246 PolarHBondContact O-N 3.26Å; K244-I247 PolarHBondContact O-N 3.26Å; K244-D248 WeakPolarHBondContact O-CB 3.36Å; K244-D248 PolarHBondContact O-N 3.17Å; K244-L265 HydrophobicContact CB-CD2 4.15Å; K244-L265 HydrophobicContact CG-CD2 4.38Å; K244-L286 HydrophobicContact CD-CD1 3.68Å; K244-L286 HydrophobicContact CD-CG 4.5Å; K244-L286 HydrophobicContact CG-CD1 4.48Å
245	E	82.4	Confident	76.2	Confident	118 Å²	118	56.9 Å²	56.9	55%	0.551	32%	0.322	S	S	*	.	H	α-helix	trans	-58.2	-40	178.2	-74.5	177	177.4	0	0	111.9	T241 R242 D248 N249	T241-E245 WeakPolarHBondContact O-CG 3.44Å; T241-E245 PolarHBondContact O-N 2.79Å; R242-E245 PolarHBondContact O-N 2.88Å; E245-D248 PolarHBondContact O-N 2.72Å; E245-N249 WeakPolarHBondContact O-CB 3.48Å; E245-N249 PolarHBondContact O-N 3.44Å; E245-N249 PolarHBondContact O-ND2 3.05Å
246	T	78.7	Confident	76.2	Confident	52 Å²	52	61.8 Å²	61.8	32%	0.319	34%	0.344	S	S	.	.	H	α-helix	trans	-66.7	-41.8	179	-54	0	0	0	0	111.6	L217 L220 R242 L243 K244 N250	L217-T246 HydrophobicContact CD1-CG2 4.34Å; L220-T246 HydrophobicContact CD1-CG2 4.14Å; R242-T246 WeakPolarHBondContact O-CB 3.09Å; R242-T246 PolarHBondContact O-N 2.9Å; R242-T246 PolarHBondContact O-OG1 3.09Å; L243-T246 PolarHBondContact O-N 3.46Å; K244-T246 VanDerWaalsContact C-N 3.26Å; K244-T246 PolarHBondContact O-N 3.26Å; T246-N250 WeakPolarHBondContact O-CB 3.32Å; T246-N250 PolarHBondContact O-N 2.92Å
247	I	76.4	Confident	76.2	Confident	3 Å²	3	66.9 Å²	66.9	2%	0.015	37%	0.368	C	S	.	.	H	α-helix	trans	-69	-40.4	177.8	-68.3	166.1	0	0	0	111	L217 W221 L243 K244 N250 Q261 R262 L265	L217-I247 HydrophobicContact CD1-CG1 4.02Å; W221-I247 HydrophobicContact CZ2-CD1 3.97Å; L243-I247 HydrophobicContact CD1-CD1 3.92Å; L243-I247 HydrophobicContact CD1-CG1 4.3Å; L243-I247 HydrophobicContact CG-CD1 3.86Å; L243-I247 VanDerWaalsContact O-CG1 3.28Å; L243-I247 WeakPolarHBondContact O-CG1 3.24Å; L243-I247 PolarHBondContact O-N 3.43Å; K244-I247 PolarHBondContact O-N 3.26Å; I247-N250 PolarHBondContact O-N 2.86Å; I247-Q261 HydrophobicContact CD1-CB 4.45Å; I247-R262 HydrophobicContact CG2-CG 3.8Å; I247-L265 HydrophobicContact CD1-CB 4.38Å; I247-L265 HydrophobicContact CD1-CD1 4.37Å; I247-L265 HydrophobicContact CD1-CD2 4.11Å
248	D	76.5	Confident	76.2	Confident	49 Å²	49	65.9 Å²	65.9	26%	0.262	36%	0.364	S	S	.	.	H	α-helix	trans	-72	-31.5	-179.5	-72.5	-12.9	0	0	0	112.1	K244 E245 R262 Q290 Y293	K244-D248 WeakPolarHBondContact O-CB 3.36Å; K244-D248 PolarHBondContact O-N 3.17Å; E245-D248 PolarHBondContact O-N 2.72Å; D248-R262 IonicContact OD1-NE 3.95Å; D248-R262 IonicContact OD1-NH2 3.13Å; D248-Q290 PolarHBondContact OD2-NE2 3.39Å; D248-Y293 PolarHBondContact OD1-OH 3.5Å
249	N	77.1	Confident	76.2	Confident	129 Å²	129	62.8 Å²	62.8	69%	0.69	35%	0.351	S	S	*	.	H	α-helix	trans	-84.4	-9.7	177.2	-68.3	-31.1	0	0	0	113.9	E245 S251	E245-N249 WeakPolarHBondContact O-CB 3.48Å; E245-N249 PolarHBondContact O-N 3.44Å; E245-N249 PolarHBondContact O-ND2 3.05Å; N249-S251 PolarHBondContact O-N 2.9Å
250	N	71.9	Confident	76.3	Confident	57 Å²	57	67.1 Å²	67.1	31%	0.305	37%	0.371	S	S	.	.			trans	-78.7	87.9	-176.8	-170.1	-6.5	0	0	0	112.2	T246 I247 V252 S253	T246-N250 WeakPolarHBondContact O-CB 3.32Å; T246-N250 PolarHBondContact O-N 2.92Å; I247-N250 PolarHBondContact O-N 2.86Å; N250-V252 VanDerWaalsContact C-N 3.33Å; N250-V252 PolarHBondContact O-N 3.47Å; N250-V252 PolarHBondContact OD1-N 3.41Å; N250-S253 PolarHBondContact O-OG 3.29Å
251	S	60.5	Low	76.1	Confident	115 Å²	115	68.6 Å²	68.6	80%	0.804	38%	0.377	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.5	-10.3	179.9	56.8	0	0	0	0	115.1	N249	N249-S251 PolarHBondContact O-N 2.9Å
252	V	60.3	Low	76	Confident	131 Å²	131	67.6 Å²	67.6	79%	0.794	37%	0.367	S	S	*	.	T	Hydrogen-bonded Turn	trans	-99.5	-6.2	-170.8	-169.3	0	0	0	0	112.5	N250	N250-V252 VanDerWaalsContact C-N 3.33Å; N250-V252 PolarHBondContact O-N 3.47Å; N250-V252 PolarHBondContact OD1-N 3.41Å
253	S	64.5	Low	76.2	Confident	26 Å²	26	64 Å²	64	18%	0.182	35%	0.354	C	S	.	.	S	Bend	trans	-84.8	147.3	178.4	61.1	0	0	0	0	112.5	N250 S258	N250-S253 PolarHBondContact O-OG 3.29Å; S253-S258 PolarHBondContact OG-OG 2.9Å
254	S	77.4	Confident	76.3	Confident	48 Å²	48	68 Å²	68	34%	0.336	37%	0.368	S	S	.	.			trans	-61.9	140.4	172.5	66.8	0	0	0	0	110.2	L256 Q257 S258	S254-L256 PolarHBondContact O-N 3.28Å; S254-Q257 PolarHBondContact O-N 3.04Å; S254-Q257 WeakPolarHBondContact OG-CB 3.35Å; S254-Q257 WeakPolarHBondContact OG-CG 3.1Å; S254-Q257 PolarHBondContact OG-N 3.21Å; S254-Q257 PolarHBondContact OG-OE1 3.06Å; S254-S258 PolarHBondContact O-N 3Å; S254-S258 PolarHBondContact O-OG 3.06Å; S254-S258 VanDerWaalsContact O-OG 3.04Å
255	P	75.9	Confident	76.6	Confident	114 Å²	114	65.9 Å²	65.9	74%	0.74	36%	0.359	S	S	*	.	H	α-helix	trans	-55.4	-31.7	-177.1	-28	34.5	0	0	0	114.1	L259	P255-L259 VanDerWaalsContact O-CB 3.31Å; P255-L259 WeakPolarHBondContact O-CB 3.41Å; P255-L259 PolarHBondContact O-N 3.15Å
256	L	79.6	Confident	76.6	Confident	127 Å²	127	60.3 Å²	60.3	67%	0.665	33%	0.333	S	S	*	.	H	α-helix	trans	-66.8	-44	175.6	-179.5	62.8	0	0	0	112.2	S254 L259 Q260	S254-L256 PolarHBondContact O-N 3.28Å; L256-L259 WeakPolarHBondContact O-CB 3.01Å; L256-L259 PolarHBondContact O-N 3.16Å; L256-Q260 PolarHBondContact O-N 3.17Å
257	Q	78.5	Confident	76.7	Confident	108 Å²	108	57.9 Å²	57.9	51%	0.505	32%	0.319	S	S	.	.	H	α-helix	trans	-69.4	-38.3	177.4	-72.8	169.5	-19.4	0	0	111.4	S254 L259 Q260 Q261	S254-Q257 PolarHBondContact O-N 3.04Å; S254-Q257 WeakPolarHBondContact OG-CB 3.35Å; S254-Q257 WeakPolarHBondContact OG-CG 3.1Å; S254-Q257 PolarHBondContact OG-N 3.21Å; S254-Q257 PolarHBondContact OG-OE1 3.06Å; Q257-L259 VanDerWaalsContact C-N 3.3Å; Q257-L259 PolarHBondContact O-N 2.9Å; Q257-Q260 PolarHBondContact O-N 3.05Å; Q257-Q261 WeakPolarHBondContact O-CB 3.31Å; Q257-Q261 VanDerWaalsContact O-CG 3.26Å; Q257-Q261 WeakPolarHBondContact O-CG 3.12Å; Q257-Q261 PolarHBondContact O-N 3.36Å
258	S	77.9	Confident	77	Confident	13 Å²	13	58.1 Å²	58.1	9%	0.091	32%	0.319	C	S	.	.	H	α-helix	trans	-63	-39.8	173.1	-32.6	0	0	0	0	110.9	S253 S254 Q261 R262	S253-S258 PolarHBondContact OG-OG 2.9Å; S254-S258 PolarHBondContact O-N 3Å; S254-S258 PolarHBondContact O-OG 3.06Å; S254-S258 VanDerWaalsContact O-OG 3.04Å; S258-Q261 PolarHBondContact O-N 2.99Å; S258-R262 WeakPolarHBondContact O-CB 3.19Å; S258-R262 VanDerWaalsContact O-CG 3.28Å; S258-R262 WeakPolarHBondContact O-CG 3.24Å; S258-R262 PolarHBondContact O-N 3.49Å
259	L	80.3	Confident	77.1	Confident	42 Å²	42	55.8 Å²	55.8	22%	0.22	31%	0.307	C	S	.	.	H	α-helix	trans	-63	-43.8	175.9	-169.8	72.3	0	0	0	111.5	P255 L256 Q257 R262 T263 A296 M300	P255-L259 VanDerWaalsContact O-CB 3.31Å; P255-L259 WeakPolarHBondContact O-CB 3.41Å; P255-L259 PolarHBondContact O-N 3.15Å; L256-L259 WeakPolarHBondContact O-CB 3.01Å; L256-L259 PolarHBondContact O-N 3.16Å; Q257-L259 VanDerWaalsContact C-N 3.3Å; Q257-L259 PolarHBondContact O-N 2.9Å; L259-R262 PolarHBondContact O-N 3.3Å; L259-T263 WeakPolarHBondContact O-CB 3.34Å; L259-T263 PolarHBondContact O-N 3.33Å; L259-T263 PolarHBondContact O-OG1 2.87Å; L259-A296 HydrophobicContact CD1-CB 3.62Å; L259-A296 HydrophobicContact CG-CB 4.4Å; L259-M300 HydrophobicContact CD2-CG 4.23Å
260	Q	80.8	Confident	77.2	Confident	92 Å²	92	49.9 Å²	49.9	43%	0.43	28%	0.275	S	S	.	.	H	α-helix	trans	-62.4	-44.8	176.1	-173.5	176.1	11.6	0	0	111.6	L256 Q257 R262 T263 W264	L256-Q260 PolarHBondContact O-N 3.17Å; Q257-Q260 PolarHBondContact O-N 3.05Å; Q260-R262 PolarHBondContact O-N 3.38Å; Q260-T263 WeakPolarHBondContact O-CB 3.17Å; Q260-T263 PolarHBondContact O-N 3.1Å; Q260-T263 VanDerWaalsContact O-N 3.12Å; Q260-W264 HydrophobicContact CG-CD2 4.35Å; Q260-W264 HydrophobicContact CG-CZ2 3.92Å; Q260-W264 PolarHBondContact O-N 3.4Å
261	Q	78.3	Confident	77.3	Confident	34 Å²	34	47.5 Å²	47.5	16%	0.159	26%	0.262	C	S	.	.	H	α-helix	trans	-62.3	-41.2	176.7	-71.8	169.7	7.5	0	0	112.2	I247 Q257 S258 T263 W264 L265	I247-Q261 HydrophobicContact CD1-CB 4.45Å; Q257-Q261 WeakPolarHBondContact O-CB 3.31Å; Q257-Q261 VanDerWaalsContact O-CG 3.26Å; Q257-Q261 WeakPolarHBondContact O-CG 3.12Å; Q257-Q261 PolarHBondContact O-N 3.36Å; S258-Q261 PolarHBondContact O-N 2.99Å; Q261-T263 VanDerWaalsContact C-N 3.3Å; Q261-T263 PolarHBondContact O-N 3.46Å; Q261-W264 PolarHBondContact O-N 3.2Å; Q261-L265 WeakPolarHBondContact O-CB 3.08Å; Q261-L265 PolarHBondContact O-N 2.88Å
262	R	80.6	Confident	78	Confident	40 Å²	40	42 Å²	42	15%	0.151	22%	0.224	C	C	.	.	H	α-helix	trans	-63	-39	172.8	-73.4	178.6	179.4	147.3	6.7	111.8	I247 D248 S258 L259 Q260 L265 I266 Y293	I247-R262 HydrophobicContact CG2-CG 3.8Å; D248-R262 IonicContact OD1-NE 3.95Å; D248-R262 IonicContact OD1-NH2 3.13Å; S258-R262 WeakPolarHBondContact O-CB 3.19Å; S258-R262 VanDerWaalsContact O-CG 3.28Å; S258-R262 WeakPolarHBondContact O-CG 3.24Å; S258-R262 PolarHBondContact O-N 3.49Å; L259-R262 PolarHBondContact O-N 3.3Å; Q260-R262 PolarHBondContact O-N 3.38Å; R262-L265 WeakPolarHBondContact O-CB 3.49Å; R262-L265 PolarHBondContact O-N 3.1Å; R262-I266 WeakPolarHBondContact O-CD1 3.36Å; R262-I266 VanDerWaalsContact O-CG1 3.28Å; R262-I266 WeakPolarHBondContact O-CG1 3.06Å; R262-I266 PolarHBondContact O-N 2.99Å; R262-Y293 HydrophobicContact CB-CD1 3.94Å; R262-Y293 HydrophobicContact CB-CE1 3.71Å; R262-Y293 HydrophobicContact CG-CD1 4.17Å; R262-Y293 HydrophobicContact CG-CE1 3.57Å
263	T	82.3	Confident	78.6	Confident	2 Å²	2	35.9 Å²	35.9	1%	0.012	19%	0.186	C	C	.	.	H	α-helix	trans	-62.9	-45.8	177.3	-56.7	0	0	0	0	111	F64 L259 Q260 Q261 L265 I266 H267 M300 C301	F64-T263 HydrophobicContact CD1-CG2 3.94Å; F64-T263 HydrophobicContact CE1-CG2 3.86Å; L259-T263 WeakPolarHBondContact O-CB 3.34Å; L259-T263 PolarHBondContact O-N 3.33Å; L259-T263 PolarHBondContact O-OG1 2.87Å; Q260-T263 WeakPolarHBondContact O-CB 3.17Å; Q260-T263 PolarHBondContact O-N 3.1Å; Q260-T263 VanDerWaalsContact O-N 3.12Å; Q261-T263 VanDerWaalsContact C-N 3.3Å; Q261-T263 PolarHBondContact O-N 3.46Å; T263-L265 VanDerWaalsContact C-N 3.32Å; T263-L265 PolarHBondContact O-N 3.39Å; T263-I266 WeakPolarHBondContact O-CB 3.33Å; T263-I266 PolarHBondContact O-N 3.15Å; T263-H267 PolarHBondContact O-N 3.46Å; T263-H267 PolarHBondContact O-ND1 3.42Å; T263-M300 HydrophobicContact CG2-CB 4.28Å; T263-C301 HydrophobicContact CG2-CB 4.35Å; T263-C301 WeakPolarHBondContact CG2-SG 3.35Å
264	W	84.1	Confident	78.8	Confident	82 Å²	82	35.3 Å²	35.3	31%	0.311	18%	0.181	S	C	.	.	H	α-helix	trans	-62.1	-41.7	173.5	-63.6	-14.5	0	0	0	111.6	F64 W221 Q260 Q261 I266 H267 W268	F64-W264 AromaticContact CD1-CD1 3.72Å; F64-W264 AromaticContact CD1-NE1 3.82Å; W221-W264 HydrophobicContact CH2-CB 3.83Å; W221-W264 HydrophobicContact CZ2-CB 4.39Å; W221-W264 HydrophobicContact CZ3-CB 4.38Å; Q260-W264 HydrophobicContact CG-CD2 4.35Å; Q260-W264 HydrophobicContact CG-CZ2 3.92Å; Q260-W264 PolarHBondContact O-N 3.4Å; Q261-W264 PolarHBondContact O-N 3.2Å; W264-I266 VanDerWaalsContact C-N 3.27Å; W264-I266 PolarHBondContact O-N 3.43Å; W264-H267 PolarHBondContact O-N 3.15Å; W264-H267 VanDerWaalsContact O-N 3.1Å; W264-W268 PolarHBondContact O-N 3.37Å
265	L	83.8	Confident	78.4	Confident	1 Å²	1	36.6 Å²	36.6	1%	0.005	18%	0.184	C	C	.	.	H	α-helix	trans	-59.9	-41.1	178.9	-171.8	70.5	0	0	0	111.1	W221 L240 L243 K244 I247 Q261 R262 T263 H267 W268 S269 Y293	W221-L265 HydrophobicContact CH2-CB 4.04Å; W221-L265 HydrophobicContact CH2-CD1 4.16Å; L240-L265 HydrophobicContact CD1-CD1 3.54Å; L240-L265 HydrophobicContact CD1-CG 4.26Å; L243-L265 HydrophobicContact CB-CD1 4.33Å; L243-L265 HydrophobicContact CD2-CD1 3.45Å; L243-L265 VanDerWaalsContact CD2-CD1 3.45Å; L243-L265 HydrophobicContact CG-CD1 3.76Å; K244-L265 HydrophobicContact CB-CD2 4.15Å; K244-L265 HydrophobicContact CG-CD2 4.38Å; I247-L265 HydrophobicContact CD1-CB 4.38Å; I247-L265 HydrophobicContact CD1-CD1 4.37Å; I247-L265 HydrophobicContact CD1-CD2 4.11Å; Q261-L265 WeakPolarHBondContact O-CB 3.08Å; Q261-L265 PolarHBondContact O-N 2.88Å; R262-L265 WeakPolarHBondContact O-CB 3.49Å; R262-L265 PolarHBondContact O-N 3.1Å; T263-L265 VanDerWaalsContact C-N 3.32Å; T263-L265 PolarHBondContact O-N 3.39Å; L265-H267 PolarHBondContact O-N 3.35Å; L265-W268 PolarHBondContact O-N 2.98Å; L265-S269 WeakPolarHBondContact O-CA 3.35Å; L265-S269 WeakPolarHBondContact O-CB 3.43Å; L265-S269 PolarHBondContact O-N 3.44Å; L265-S269 PolarHBondContact O-OG 2.93Å; L265-S269 VanDerWaalsContact O-OG 3.06Å; L265-Y293 HydrophobicContact CD2-CE1 3.84Å
266	I	82.6	Confident	78	Confident	1 Å²	1	32.7 Å²	32.7	1%	0.005	16%	0.155	C	C	.	.	H	α-helix	trans	-57.8	-49.6	176	-69.6	158.4	0	0	0	110.3	R262 T263 W264 W268 S269 L270 F287 Y293 A296 I297 I304	R262-I266 WeakPolarHBondContact O-CD1 3.36Å; R262-I266 VanDerWaalsContact O-CG1 3.28Å; R262-I266 WeakPolarHBondContact O-CG1 3.06Å; R262-I266 PolarHBondContact O-N 2.99Å; T263-I266 WeakPolarHBondContact O-CB 3.33Å; T263-I266 PolarHBondContact O-N 3.15Å; W264-I266 VanDerWaalsContact C-N 3.27Å; W264-I266 PolarHBondContact O-N 3.43Å; I266-W268 PolarHBondContact O-N 3.1Å; I266-S269 PolarHBondContact O-N 3.39Å; I266-S269 PolarHBondContact O-OG 3.43Å; I266-L270 PolarHBondContact O-N 3.18Å; I266-F287 HydrophobicContact CB-CE1 4Å; I266-F287 HydrophobicContact CB-CZ 4.45Å; I266-F287 HydrophobicContact CG1-CD1 4.19Å; I266-F287 HydrophobicContact CG1-CE1 3.72Å; I266-F287 HydrophobicContact CG2-CD1 4.46Å; I266-F287 HydrophobicContact CG2-CE1 3.72Å; I266-F287 HydrophobicContact CG2-CZ 3.84Å; I266-Y293 HydrophobicContact CD1-CD1 4.03Å; I266-Y293 HydrophobicContact CG1-CD1 3.94Å; I266-A296 HydrophobicContact CD1-CB 4.09Å; I266-I297 HydrophobicContact CD1-CD1 4.41Å; I266-I297 HydrophobicContact CD1-CG1 3.85Å; I266-I304 HydrophobicContact CG2-CB 4.39Å; I266-I304 HydrophobicContact CG2-CD1 4.16Å; I266-I304 HydrophobicContact CG2-CG1 3.9Å; I266-I304 HydrophobicContact CG2-CG2 3.76Å
267	H	81.9	Confident	77.3	Confident	2 Å²	2	31.5 Å²	31.5	1%	0.009	16%	0.156	C	C	.	.	H	α-helix	trans	-63.6	-42.2	-179.7	-70.2	75.7	0	0	0	112.2	F64 L65 T263 W264 L265 L270 F271 C301 H303	F64-H267 HydrophobicContact CB-CB 4.19Å; F64-H267 AromaticContact CD2-CD2 3.95Å; F64-H267 AromaticContact CD2-CE1 3.67Å; F64-H267 AromaticContact CD2-NE2 3.45Å; F64-H267 WeakPolarHBondContact CD2-NE2 3.47Å; F64-H267 AromaticContact CG-CE1 3.79Å; F64-H267 AromaticContact CG-ND1 3.95Å; F64-H267 AromaticContact CG-NE2 3.94Å; L65-H267 HydrophobicContact CD2-CB 4.4Å; T263-H267 PolarHBondContact O-N 3.46Å; T263-H267 PolarHBondContact O-ND1 3.42Å; W264-H267 PolarHBondContact O-N 3.15Å; W264-H267 VanDerWaalsContact O-N 3.1Å; L265-H267 PolarHBondContact O-N 3.35Å; H267-L270 WeakPolarHBondContact O-CB 3.39Å; H267-L270 PolarHBondContact O-N 3.38Å; H267-F271 VanDerWaalsContact O-CD2 3.31Å; H267-F271 WeakPolarHBondContact O-CD2 3.22Å; H267-C301 PolarHBondContact CE1-SG 3.43Å; H267-H303 AromaticContact CD2-NE2 3.85Å; H267-H303 AromaticContact CE1-NE2 3.88Å; H267-H303 AromaticContact NE2-CE1 3.51Å; H267-H303 AromaticContact NE2-NE2 2.9Å; H267-H303 PolarHBondContact NE2-NE2 3.46Å
268	W	82	Confident	76.5	Confident	8 Å²	8	33.9 Å²	33.9	3%	0.03	16%	0.164	C	C	.	.	H	α-helix	trans	-76.2	-35.6	-177.4	-68.8	42.8	0	0	0	111.8	F64 L65 D66 L69 W221 L224 A225 W264 L265 I266 L270 F271	F64-W268 PolarHBondContact O-NE1 3.07Å; L65-W268 HydrophobicContact CD2-CG 4.36Å; D66-W268 HydrophobicContact CB-CH2 4.01Å; D66-W268 HydrophobicContact CB-CZ2 3.83Å; D66-W268 WeakPolarHBondContact OD2-CH2 3.47Å; L69-W268 HydrophobicContact CD1-CD2 4.04Å; L69-W268 HydrophobicContact CD1-CE3 4.04Å; L69-W268 HydrophobicContact CD1-CH2 4.31Å; L69-W268 HydrophobicContact CD1-CZ2 4.24Å; L69-W268 HydrophobicContact CD1-CZ3 4.21Å; W221-W268 AromaticContact CE3-CD2 3.92Å; W221-W268 HydrophobicContact CE3-CD2 3.92Å; W221-W268 AromaticContact CE3-CE3 3.65Å; W221-W268 HydrophobicContact CE3-CE3 3.65Å; W221-W268 AromaticContact CE3-CH2 3.84Å; W221-W268 HydrophobicContact CE3-CH2 3.84Å; W221-W268 HydrophobicContact CE3-CZ2 4.15Å; W221-W268 AromaticContact CE3-CZ3 3.58Å; W221-W268 HydrophobicContact CE3-CZ3 3.58Å; W221-W268 HydrophobicContact CZ3-CB 4.35Å; W221-W268 AromaticContact CZ3-CD2 3.63Å; W221-W268 HydrophobicContact CZ3-CD2 3.63Å; W221-W268 AromaticContact CZ3-CE3 3.77Å; W221-W268 HydrophobicContact CZ3-CE3 3.77Å; W221-W268 AromaticContact CZ3-CG 3.94Å; W221-W268 HydrophobicContact CZ3-CG 3.94Å; W221-W268 HydrophobicContact CZ3-CH2 4.48Å; W221-W268 HydrophobicContact CZ3-CZ2 4.42Å; W221-W268 HydrophobicContact CZ3-CZ3 4.17Å; L224-W268 HydrophobicContact CD2-CB 4.25Å; L224-W268 HydrophobicContact CD2-CD2 4.45Å; L224-W268 HydrophobicContact CD2-CE3 3.46Å; L224-W268 VanDerWaalsContact CD2-CE3 3.46Å; L224-W268 HydrophobicContact CD2-CZ3 4.15Å; A225-W268 HydrophobicContact CB-CH2 4.08Å; A225-W268 HydrophobicContact CB-CZ3 3.72Å; W264-W268 PolarHBondContact O-N 3.37Å; L265-W268 PolarHBondContact O-N 2.98Å; I266-W268 PolarHBondContact O-N 3.1Å; W268-L270 PolarHBondContact O-N 3.26Å; W268-F271 WeakPolarHBondContact O-CB 3.45Å; W268-F271 PolarHBondContact O-N 3.17Å
269	S	79.8	Confident	75.8	Confident	0 Å²	0	33.3 Å²	33.3	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-61.2	-30	173.4	73	0	0	0	0	111.9	L265 I266 F271 V272 F273 F287	L265-S269 WeakPolarHBondContact O-CA 3.35Å; L265-S269 WeakPolarHBondContact O-CB 3.43Å; L265-S269 PolarHBondContact O-N 3.44Å; L265-S269 PolarHBondContact O-OG 2.93Å; L265-S269 VanDerWaalsContact O-OG 3.06Å; I266-S269 PolarHBondContact O-N 3.39Å; I266-S269 PolarHBondContact O-OG 3.43Å; S269-F271 VanDerWaalsContact C-N 3.33Å; S269-F271 PolarHBondContact O-N 3.49Å; S269-V272 PolarHBondContact O-N 3.44Å; S269-F273 WeakPolarHBondContact O-CB 3.38Å; S269-F273 WeakPolarHBondContact O-CD2 3.5Å; S269-F273 VanDerWaalsContact O-CG 3.24Å; S269-F273 WeakPolarHBondContact O-CG 3.46Å; S269-F273 PolarHBondContact O-N 2.86Å; S269-F287 WeakPolarHBondContact OG-CZ 3.29Å
270	L	77.9	Confident	75.1	Confident	4 Å²	4	33 Å²	33	2%	0.021	16%	0.156	C	C	.	.	H	α-helix	trans	-58.8	-43.8	175.9	-154.8	63.7	0	0	0	112.1	I266 H267 W268 V272 F273 F274 F287 I304 Y307	I266-L270 PolarHBondContact O-N 3.18Å; H267-L270 WeakPolarHBondContact O-CB 3.39Å; H267-L270 PolarHBondContact O-N 3.38Å; W268-L270 PolarHBondContact O-N 3.26Å; L270-V272 VanDerWaalsContact C-N 3.31Å; L270-V272 PolarHBondContact O-N 3.41Å; L270-F273 PolarHBondContact O-N 3.46Å; L270-F274 HydrophobicContact CD1-CD2 3.78Å; L270-F274 HydrophobicContact CD1-CE2 3.26Å; L270-F274 HydrophobicContact CD1-CZ 4.25Å; L270-F274 HydrophobicContact CD2-CE2 4.13Å; L270-F274 HydrophobicContact CG-CD2 3.64Å; L270-F274 HydrophobicContact CG-CE2 3.46Å; L270-F274 VanDerWaalsContact CG-CE2 3.46Å; L270-F274 VanDerWaalsContact O-CD2 3.27Å; L270-F274 WeakPolarHBondContact O-CD2 3.39Å; L270-F274 PolarHBondContact O-N 2.99Å; L270-F274 VanDerWaalsContact O-N 3.1Å; L270-F287 HydrophobicContact CD1-CE2 4.48Å; L270-I304 HydrophobicContact CD2-CD1 4.26Å; L270-Y307 HydrophobicContact CD1-CG 4.25Å; L270-Y307 HydrophobicContact CD2-CD1 4.16Å; L270-Y307 HydrophobicContact CD2-CD2 3.45Å; L270-Y307 VanDerWaalsContact CD2-CD2 3.45Å; L270-Y307 HydrophobicContact CD2-CE2 3.88Å; L270-Y307 HydrophobicContact CD2-CG 3.61Å; L270-Y307 HydrophobicContact CG-CG 4.39Å
271	F	74.1	Confident	74.6	Confident	8 Å²	8	30.9 Å²	30.9	4%	0.035	15%	0.148	C	C	.	.	H	α-helix	trans	-59.7	-42.6	176.7	-76	-104.6	0	0	0	111.6	L65 L73 I228 W233 H267 W268 S269 N275 F375	L65-F271 HydrophobicContact CD1-CE2 3.69Å; L65-F271 HydrophobicContact CD1-CZ 3.49Å; L65-F271 VanDerWaalsContact CD1-CZ 3.49Å; L65-F271 HydrophobicContact CD2-CD2 4.23Å; L65-F271 HydrophobicContact CD2-CE2 3.37Å; L65-F271 HydrophobicContact CD2-CZ 3.9Å; L65-F271 HydrophobicContact CG-CE2 4.17Å; L65-F271 HydrophobicContact CG-CZ 4.36Å; L73-F271 HydrophobicContact CD1-CZ 4.14Å; I228-F271 HydrophobicContact CD1-CB 4.25Å; I228-F271 HydrophobicContact CG2-CB 4.25Å; I228-F271 HydrophobicContact CG2-CD1 4.24Å; W233-F271 VanDerWaalsContact CZ3-O 3.32Å; W233-F271 WeakPolarHBondContact CZ3-O 3.48Å; H267-F271 VanDerWaalsContact O-CD2 3.31Å; H267-F271 WeakPolarHBondContact O-CD2 3.22Å; W268-F271 WeakPolarHBondContact O-CB 3.45Å; W268-F271 PolarHBondContact O-N 3.17Å; S269-F271 VanDerWaalsContact C-N 3.33Å; S269-F271 PolarHBondContact O-N 3.49Å; F271-N275 PolarHBondContact O-ND2 3.09Å; F271-F375 HydrophobicContact CB-CE1 4.27Å; F271-F375 AromaticContact CD1-CE1 3.47Å; F271-F375 HydrophobicContact CD1-CE1 3.47Å; F271-F375 VanDerWaalsContact CD1-CE1 3.47Å; F271-F375 AromaticContact CD1-CZ 3.51Å; F271-F375 HydrophobicContact CD1-CZ 3.51Å; F271-F375 HydrophobicContact CD2-CE1 4.2Å; F271-F375 AromaticContact CD2-CZ 3.85Å; F271-F375 HydrophobicContact CD2-CZ 3.85Å; F271-F375 AromaticContact CE1-CE1 3.82Å; F271-F375 HydrophobicContact CE1-CE1 3.82Å; F271-F375 AromaticContact CE1-CZ 3.37Å; F271-F375 HydrophobicContact CE1-CZ 3.37Å; F271-F375 HydrophobicContact CE2-CE1 4.43Å; F271-F375 HydrophobicContact CE2-CE2 4.41Å; F271-F375 AromaticContact CE2-CZ 3.65Å; F271-F375 HydrophobicContact CE2-CZ 3.65Å; F271-F375 AromaticContact CG-CE1 3.71Å; F271-F375 HydrophobicContact CG-CE1 3.71Å; F271-F375 AromaticContact CG-CZ 3.78Å; F271-F375 HydrophobicContact CG-CZ 3.78Å; F271-F375 HydrophobicContact CZ-CE1 4.29Å; F271-F375 HydrophobicContact CZ-CE2 4.32Å; F271-F375 AromaticContact CZ-CZ 3.45Å; F271-F375 HydrophobicContact CZ-CZ 3.45Å; F271-F375 VanDerWaalsContact CZ-CZ 3.45Å
272	V	75.8	Confident	74.2	Confident	0 Å²	0	32.2 Å²	32.2	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-73.1	-43.9	-177.5	-177.7	0	0	0	0	111	I228 A236 M237 S269 L270 H276	I228-V272 HydrophobicContact CD1-CG2 3.95Å; I228-V272 HydrophobicContact CG1-CG2 3.92Å; A236-V272 HydrophobicContact CB-CG1 4.06Å; A236-V272 HydrophobicContact CB-CG2 3.97Å; M237-V272 HydrophobicContact CB-CG1 4.48Å; S269-V272 PolarHBondContact O-N 3.44Å; L270-V272 VanDerWaalsContact C-N 3.31Å; L270-V272 PolarHBondContact O-N 3.41Å; V272-H276 WeakPolarHBondContact O-CB 3.48Å; V272-H276 PolarHBondContact O-N 3.39Å; V272-H276 VanDerWaalsContact O-N 3.16Å
273	F	72.1	Confident	74	Confident	2 Å²	2	30.4 Å²	30.4	1%	0.009	15%	0.149	C	C	.	.	H	α-helix	trans	-77.5	-27.7	-172.3	-67.5	-44.6	0	0	0	114.6	M237 L240 S269 L270 H276 N282 I283 L286	M237-F273 HydrophobicContact CE-CE1 3.8Å; M237-F273 HydrophobicContact SD-CD1 4.07Å; M237-F273 HydrophobicContact SD-CE1 3.54Å; M237-F273 VanDerWaalsContact SD-CE1 3.54Å; L240-F273 HydrophobicContact CD2-CD1 4.43Å; L240-F273 HydrophobicContact CD2-CE1 3.72Å; L240-F273 HydrophobicContact CD2-CE2 3.83Å; L240-F273 HydrophobicContact CD2-CZ 3.38Å; S269-F273 WeakPolarHBondContact O-CB 3.38Å; S269-F273 WeakPolarHBondContact O-CD2 3.5Å; S269-F273 VanDerWaalsContact O-CG 3.24Å; S269-F273 WeakPolarHBondContact O-CG 3.46Å; S269-F273 PolarHBondContact O-N 2.86Å; L270-F273 PolarHBondContact O-N 3.46Å; F273-H276 VanDerWaalsContact O-O 3.09Å; F273-N282 HydrophobicContact CD1-CB 4.47Å; F273-N282 HydrophobicContact CE1-CB 3.74Å; F273-N282 HydrophobicContact CZ-CB 4.06Å; F273-I283 HydrophobicContact CB-CD1 3.39Å; F273-I283 HydrophobicContact CB-CG1 3.44Å; F273-I283 VanDerWaalsContact CB-CG1 3.44Å; F273-I283 HydrophobicContact CD1-CG1 4.42Å; F273-I283 HydrophobicContact CD2-CD1 4.21Å; F273-I283 HydrophobicContact CD2-CG1 3.37Å; F273-I283 HydrophobicContact CE2-CG1 4.13Å; F273-I283 HydrophobicContact CG-CD1 4.1Å; F273-I283 HydrophobicContact CG-CG1 3.54Å; F273-L286 HydrophobicContact CZ-CD1 4.4Å
274	F	69.6	Low	73.5	Confident	14 Å²	14	30.6 Å²	30.6	6%	0.061	15%	0.15	C	C	.	.	H	α-helix	trans	-72.2	-32.4	175.2	-86.5	-67	0	0	0	112.8	L270 Y307 F375 L376	L270-F274 HydrophobicContact CD1-CD2 3.78Å; L270-F274 HydrophobicContact CD1-CE2 3.26Å; L270-F274 HydrophobicContact CD1-CZ 4.25Å; L270-F274 HydrophobicContact CD2-CE2 4.13Å; L270-F274 HydrophobicContact CG-CD2 3.64Å; L270-F274 HydrophobicContact CG-CE2 3.46Å; L270-F274 VanDerWaalsContact CG-CE2 3.46Å; L270-F274 VanDerWaalsContact O-CD2 3.27Å; L270-F274 WeakPolarHBondContact O-CD2 3.39Å; L270-F274 PolarHBondContact O-N 2.99Å; L270-F274 VanDerWaalsContact O-N 3.1Å; F274-Y307 AromaticContact CE2-CD1 3.76Å; F274-Y307 HydrophobicContact CE2-CD1 3.76Å; F274-Y307 HydrophobicContact CE2-CG 4.06Å; F274-Y307 AromaticContact CZ-CD1 3.86Å; F274-Y307 HydrophobicContact CZ-CD1 3.86Å; F274-Y307 HydrophobicContact CZ-CG 4.27Å; F274-F375 HydrophobicContact CB-CB 4.38Å; F274-F375 HydrophobicContact CB-CD1 4.4Å; F274-F375 HydrophobicContact CD2-CB 3.86Å; F274-F375 HydrophobicContact CD2-CD1 4.41Å; F274-F375 HydrophobicContact CD2-CG 4.24Å; F274-F375 HydrophobicContact CE2-CB 4.28Å; F274-F375 HydrophobicContact CG-CB 4.07Å; F274-L376 HydrophobicContact CE1-CD2 3.84Å; F274-L376 HydrophobicContact CZ-CD2 3.97Å
275	N	68.3	Low	73	Confident	75 Å²	75	29.9 Å²	29.9	40%	0.401	15%	0.152	S	C	.	.	H	α-helix	trans	-84.1	-22.5	179.3	-67.8	-37.8	0	0	0	112.8	W233 F271	W233-N275 HydrophobicContact CD2-CB 3.51Å; W233-N275 VanDerWaalsContact CE2-CB 3.43Å; W233-N275 HydrophobicContact CE3-CB 3.94Å; W233-N275 HydrophobicContact CG-CB 3.94Å; W233-N275 HydrophobicContact CH2-CB 4.24Å; W233-N275 WeakPolarHBondContact CH2-ND2 3.48Å; W233-N275 HydrophobicContact CZ2-CB 3.84Å; W233-N275 WeakPolarHBondContact CZ2-ND2 3.42Å; W233-N275 HydrophobicContact CZ3-CB 4.27Å; F271-N275 PolarHBondContact O-ND2 3.09Å
276	H	68.5	Low	72.4	Confident	31 Å²	31	30.5 Å²	30.5	14%	0.144	16%	0.156	C	C	.	.	S	Bend	trans	-94.8	121.1	176.6	-165.9	-83.2	0	0	0	112.5	D234 V272 F273 K278 G279	D234-H276 IonicContact OD1-CD2 3.53Å; D234-H276 PolarHBondContact OD1-CD2 3.08Å; D234-H276 IonicContact OD1-NE2 3.55Å; D234-H276 PolarHBondContact OD1-NE2 3.46Å; V272-H276 WeakPolarHBondContact O-CB 3.48Å; V272-H276 PolarHBondContact O-N 3.39Å; V272-H276 VanDerWaalsContact O-N 3.16Å; F273-H276 VanDerWaalsContact O-O 3.09Å; H276-K278 VanDerWaalsContact C-N 3.27Å; H276-K278 VanDerWaalsContact CE1-CB 3.43Å; H276-K278 WeakPolarHBondContact CE1-CB 3.31Å; H276-K278 PolarHBondContact ND1-N 3.21Å; H276-K278 PolarHBondContact O-N 2.8Å; H276-K278 VanDerWaalsContact O-N 3.17Å; H276-G279 PolarHBondContact ND1-N 3.21Å; H276-G279 PolarHBondContact O-N 2.7Å
277	P	63.6	Low	71.7	Confident	103 Å²	103	30.5 Å²	30.5	67%	0.669	16%	0.156	S	C	*	.	T	Hydrogen-bonded Turn	trans	-65.1	-24.7	-176.2	24.3	-33.4	0	0	0	114.2
278	K	62.9	Low	71.1	Confident	158 Å²	158	31.6 Å²	31.6	69%	0.687	16%	0.161	S	C	*	.	T	Hydrogen-bonded Turn	trans	-91	-4.3	172.2	-44.5	179	177.6	169.8	0	113.9	H276 R280	H276-K278 VanDerWaalsContact C-N 3.27Å; H276-K278 VanDerWaalsContact CE1-CB 3.43Å; H276-K278 WeakPolarHBondContact CE1-CB 3.31Å; H276-K278 PolarHBondContact ND1-N 3.21Å; H276-K278 PolarHBondContact O-N 2.8Å; H276-K278 VanDerWaalsContact O-N 3.17Å; K278-R280 PolarHBondContact O-N 3.42Å
279	G	62.1	Low	70.5	Confident	0 Å²	0	37.4 Å²	37.4	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-67.7	-23.4	177.7	0	0	0	0	0	112.7	H276 D281 N282 I283	H276-G279 PolarHBondContact ND1-N 3.21Å; H276-G279 PolarHBondContact O-N 2.7Å; G279-D281 PolarHBondContact O-N 2.79Å; G279-N282 CarbonylContact O-C 3.59Å; G279-N282 PolarHBondContact O-N 3.29Å; G279-N282 VanDerWaalsContact O-N 3.1Å; G279-I283 PolarHBondContact O-N 3.4Å
280	R	65.4	Low	70.2	Confident	36 Å²	36	39.2 Å²	39.2	14%	0.136	19%	0.193	C	C	.	.	H	α-helix	trans	-62.9	-36.8	-176	-59.6	-176.4	-176.4	177.8	0.7	113.9	K278 I284 D382	K278-R280 PolarHBondContact O-N 3.42Å; R280-I284 PolarHBondContact O-N 3.46Å; R280-D382 IonicContact NH1-OD2 3.82Å; R280-D382 PolarHBondContact NH1-OD2 2.63Å
281	D	69.8	Low	70.1	Confident	48 Å²	48	42.9 Å²	42.9	26%	0.257	22%	0.217	S	C	.	.	H	α-helix	trans	-69.4	-40.8	173.4	-78.9	-33.5	0	0	0	111.3	G279 I283 I284 D285 N315 K320	G279-D281 PolarHBondContact O-N 2.79Å; D281-I283 VanDerWaalsContact C-N 3.32Å; D281-I283 PolarHBondContact O-N 3.25Å; D281-I284 PolarHBondContact O-N 3.47Å; D281-I284 VanDerWaalsContact O-N 3.15Å; D281-D285 PolarHBondContact O-N 3.28Å; D281-N315 PolarHBondContact OD1-ND2 3.49Å; D281-K320 IonicContact OD1-NZ 3.61Å; D281-K320 IonicContact OD2-NZ 2.88Å
282	N	71.4	Confident	70.3	Confident	61 Å²	61	46.4 Å²	46.4	33%	0.326	23%	0.233	S	C	.	.	H	α-helix	trans	-68	-30.9	179	-65.6	-34.4	0	0	0	112.3	M237 F273 G279 I284 D285 L286	M237-N282 HydrophobicContact CE-CB 4.21Å; M237-N282 WeakPolarHBondContact CE-ND2 3.48Å; F273-N282 HydrophobicContact CD1-CB 4.47Å; F273-N282 HydrophobicContact CE1-CB 3.74Å; F273-N282 HydrophobicContact CZ-CB 4.06Å; G279-N282 CarbonylContact O-C 3.59Å; G279-N282 PolarHBondContact O-N 3.29Å; G279-N282 VanDerWaalsContact O-N 3.1Å; N282-I284 VanDerWaalsContact C-N 3.33Å; N282-D285 PolarHBondContact O-N 3.47Å; N282-L286 WeakPolarHBondContact O-CB 3.32Å; N282-L286 PolarHBondContact O-N 3.26Å
283	I	75.4	Confident	70.3	Confident	2 Å²	2	46.4 Å²	46.4	1%	0.01	23%	0.233	C	C	.	.	H	α-helix	trans	-56.8	-50.2	169.4	-75.9	175.2	0	0	0	109.9	F273 G279 D281 D285 L286 F287 A311	F273-I283 HydrophobicContact CB-CD1 3.39Å; F273-I283 HydrophobicContact CB-CG1 3.44Å; F273-I283 VanDerWaalsContact CB-CG1 3.44Å; F273-I283 HydrophobicContact CD1-CG1 4.42Å; F273-I283 HydrophobicContact CD2-CD1 4.21Å; F273-I283 HydrophobicContact CD2-CG1 3.37Å; F273-I283 HydrophobicContact CE2-CG1 4.13Å; F273-I283 HydrophobicContact CG-CD1 4.1Å; F273-I283 HydrophobicContact CG-CG1 3.54Å; G279-I283 PolarHBondContact O-N 3.4Å; D281-I283 VanDerWaalsContact C-N 3.32Å; D281-I283 PolarHBondContact O-N 3.25Å; I283-D285 VanDerWaalsContact C-N 3.33Å; I283-D285 PolarHBondContact O-N 3.1Å; I283-L286 PolarHBondContact O-N 3.37Å; I283-F287 HydrophobicContact CB-CD2 4.41Å; I283-F287 HydrophobicContact CB-CE2 4.47Å; I283-F287 HydrophobicContact CG1-CE2 4.35Å; I283-F287 HydrophobicContact CG2-CD2 3.52Å; I283-F287 HydrophobicContact CG2-CE2 3.8Å; I283-F287 WeakPolarHBondContact O-CB 3.35Å; I283-F287 PolarHBondContact O-N 2.94Å; I283-A311 HydrophobicContact CD1-CB 4.03Å; I283-A311 HydrophobicContact CG2-CB 3.9Å
284	I	71.8	Confident	70.6	Confident	6 Å²	6	47.7 Å²	47.7	3%	0.031	24%	0.24	C	C	.	.	H	α-helix	trans	-63.2	-46.2	-177.5	-64.5	179.8	0	0	0	109.5	R280 D281 N282 L286 L288 V312 N315 V324	R280-I284 PolarHBondContact O-N 3.46Å; D281-I284 PolarHBondContact O-N 3.47Å; D281-I284 VanDerWaalsContact O-N 3.15Å; N282-I284 VanDerWaalsContact C-N 3.33Å; I284-L286 VanDerWaalsContact C-N 3.35Å; I284-L286 PolarHBondContact O-N 3.19Å; I284-L288 WeakPolarHBondContact O-CA 3.45Å; I284-L288 WeakPolarHBondContact O-CB 3.36Å; I284-L288 PolarHBondContact O-N 2.79Å; I284-V312 HydrophobicContact CD1-CG2 4.25Å; I284-V312 HydrophobicContact CG1-CG2 4.05Å; I284-N315 HydrophobicContact CD1-CB 4.14Å; I284-N315 WeakPolarHBondContact CD1-ND2 3.32Å; I284-V324 HydrophobicContact CG2-CB 4.49Å; I284-V324 HydrophobicContact CG2-CG1 4.1Å; I284-V324 HydrophobicContact CG2-CG2 3.62Å
285	D	73.3	Confident	71.1	Confident	67 Å²	67	51 Å²	51	36%	0.358	26%	0.259	S	S	.	.	H	α-helix	trans	-68.4	-36.6	-178	-67	-14.6	0	0	0	112.2	D281 N282 I283 Y289	D281-D285 PolarHBondContact O-N 3.28Å; N282-D285 PolarHBondContact O-N 3.47Å; I283-D285 VanDerWaalsContact C-N 3.33Å; I283-D285 PolarHBondContact O-N 3.1Å; D285-Y289 HydrophobicContact CB-CD2 4.15Å; D285-Y289 WeakPolarHBondContact O-CB 3.43Å; D285-Y289 PolarHBondContact O-N 3.29Å; D285-Y289 VanDerWaalsContact OD1-CD2 3.31Å; D285-Y289 WeakPolarHBondContact OD1-CD2 3.47Å; D285-Y289 WeakPolarHBondContact OD1-CE2 3.4Å
286	L	72.3	Confident	71.6	Confident	15 Å²	15	47.5 Å²	47.5	8%	0.079	24%	0.239	C	C	.	.	H	α-helix	trans	-81.7	-39.6	-176	-166.3	143	0	0	0	113	K244 F273 N282 I283 I284 Y293	K244-L286 HydrophobicContact CD-CD1 3.68Å; K244-L286 HydrophobicContact CD-CG 4.5Å; K244-L286 HydrophobicContact CG-CD1 4.48Å; F273-L286 HydrophobicContact CZ-CD1 4.4Å; N282-L286 WeakPolarHBondContact O-CB 3.32Å; N282-L286 PolarHBondContact O-N 3.26Å; I283-L286 PolarHBondContact O-N 3.37Å; I284-L286 VanDerWaalsContact C-N 3.35Å; I284-L286 PolarHBondContact O-N 3.19Å; L286-Y293 HydrophobicContact CD2-CG 4.47Å
287	F	68.5	Low	72.1	Confident	1 Å²	1	46 Å²	46	0%	0.004	23%	0.233	C	C	.	.	H	α-helix	trans	-86.8	-31.9	-179.7	-62.9	-29.4	0	0	0	113.4	I266 S269 L270 I283 I297 L308	I266-F287 HydrophobicContact CB-CE1 4Å; I266-F287 HydrophobicContact CB-CZ 4.45Å; I266-F287 HydrophobicContact CG1-CD1 4.19Å; I266-F287 HydrophobicContact CG1-CE1 3.72Å; I266-F287 HydrophobicContact CG2-CD1 4.46Å; I266-F287 HydrophobicContact CG2-CE1 3.72Å; I266-F287 HydrophobicContact CG2-CZ 3.84Å; S269-F287 WeakPolarHBondContact OG-CZ 3.29Å; L270-F287 HydrophobicContact CD1-CE2 4.48Å; I283-F287 HydrophobicContact CB-CD2 4.41Å; I283-F287 HydrophobicContact CB-CE2 4.47Å; I283-F287 HydrophobicContact CG1-CE2 4.35Å; I283-F287 HydrophobicContact CG2-CD2 3.52Å; I283-F287 HydrophobicContact CG2-CE2 3.8Å; I283-F287 WeakPolarHBondContact O-CB 3.35Å; I283-F287 PolarHBondContact O-N 2.94Å; F287-I297 HydrophobicContact CB-CD1 4.28Å; F287-I297 HydrophobicContact CD1-CD1 4.42Å; F287-I297 HydrophobicContact CG-CD1 4.38Å; F287-L308 HydrophobicContact CB-CD1 3.7Å; F287-L308 HydrophobicContact CD2-CD1 4.23Å; F287-L308 HydrophobicContact CG-CD1 4.36Å
288	L	68.3	Low	72.5	Confident	24 Å²	24	43.9 Å²	43.9	13%	0.126	21%	0.214	C	C	.	.	H	α-helix	trans	-98.1	-42.8	-173.4	-131.4	85.9	0	0	0	113.5	I284 L308 V324 D327	I284-L288 WeakPolarHBondContact O-CA 3.45Å; I284-L288 WeakPolarHBondContact O-CB 3.36Å; I284-L288 PolarHBondContact O-N 2.79Å; L288-L308 HydrophobicContact CD1-CD1 4.17Å; L288-L308 HydrophobicContact CD1-CD2 3.82Å; L288-V324 HydrophobicContact CD2-CB 4.18Å; L288-V324 HydrophobicContact CD2-CG1 3.56Å; L288-V324 HydrophobicContact CD2-CG2 4.24Å; L288-D327 HydrophobicContact CD2-CB 4.42Å
289	Y	70.4	Confident	73.1	Confident	130 Å²	130	40.8 Å²	40.8	51%	0.51	21%	0.208	S	C	.	.	S	Bend	trans	-83.3	-16.9	-177.3	-66.5	-51	0	0	0	113.6	D285 P291	D285-Y289 HydrophobicContact CB-CD2 4.15Å; D285-Y289 WeakPolarHBondContact O-CB 3.43Å; D285-Y289 PolarHBondContact O-N 3.29Å; D285-Y289 VanDerWaalsContact OD1-CD2 3.31Å; D285-Y289 WeakPolarHBondContact OD1-CD2 3.47Å; D285-Y289 WeakPolarHBondContact OD1-CE2 3.4Å; Y289-P291 VanDerWaalsContact O-CD 3.27Å; Y289-P291 WeakPolarHBondContact O-CD 3.1Å
290	Q	73.3	Confident	73.6	Confident	39 Å²	39	45.4 Å²	45.4	18%	0.182	23%	0.231	C	C	.	.			trans	-101.8	102	179.5	-160.2	160.8	-7.3	0	0	110.9	D248 Q292 Y293 L294	D248-Q290 PolarHBondContact OD2-NE2 3.39Å; Q290-Q292 PolarHBondContact O-N 3.31Å; Q290-Q292 VanDerWaalsContact O-N 3.07Å; Q290-Y293 HydrophobicContact CB-CD2 3.86Å; Q290-Y293 VanDerWaalsContact CD-CE2 3.44Å; Q290-Y293 HydrophobicContact CG-CD2 3.66Å; Q290-Y293 HydrophobicContact CG-CE2 4.01Å; Q290-Y293 PolarHBondContact O-N 2.93Å; Q290-Y293 VanDerWaalsContact O-N 3.09Å; Q290-L294 PolarHBondContact O-N 2.66Å
291	P	75.1	Confident	73.6	Confident	81 Å²	81	43.8 Å²	43.8	53%	0.526	23%	0.225	S	C	.	.	H	α-helix	trans	-64	-22.1	-171.9	24.9	-34.6	0	0	0	113	Y289 L294 N295	Y289-P291 VanDerWaalsContact O-CD 3.27Å; Y289-P291 WeakPolarHBondContact O-CD 3.1Å; P291-L294 PolarHBondContact O-N 3.26Å; P291-N295 WeakPolarHBondContact O-CB 3.45Å; P291-N295 PolarHBondContact O-N 3.27Å; P291-N295 PolarHBondContact O-ND2 3.01Å; P291-N295 PolarHBondContact O-OD1 3.16Å
292	Q	77.6	Confident	73.8	Confident	82 Å²	82	42.3 Å²	42.3	38%	0.383	22%	0.218	S	C	.	.	H	α-helix	trans	-66.3	-36	177.4	-63.8	176.1	3	0	0	112.8	Q290	Q290-Q292 PolarHBondContact O-N 3.31Å; Q290-Q292 VanDerWaalsContact O-N 3.07Å
293	Y	77.1	Confident	74.1	Confident	0 Å²	0	39.5 Å²	39.5	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-81.2	-36.5	176.2	-68.3	-80.1	0	0	0	110.6	D248 R262 L265 I266 L286 Q290 N295 A296 I297	D248-Y293 PolarHBondContact OD1-OH 3.5Å; R262-Y293 HydrophobicContact CB-CD1 3.94Å; R262-Y293 HydrophobicContact CB-CE1 3.71Å; R262-Y293 HydrophobicContact CG-CD1 4.17Å; R262-Y293 HydrophobicContact CG-CE1 3.57Å; L265-Y293 HydrophobicContact CD2-CE1 3.84Å; I266-Y293 HydrophobicContact CD1-CD1 4.03Å; I266-Y293 HydrophobicContact CG1-CD1 3.94Å; L286-Y293 HydrophobicContact CD2-CG 4.47Å; Q290-Y293 HydrophobicContact CB-CD2 3.86Å; Q290-Y293 VanDerWaalsContact CD-CE2 3.44Å; Q290-Y293 HydrophobicContact CG-CD2 3.66Å; Q290-Y293 HydrophobicContact CG-CE2 4.01Å; Q290-Y293 PolarHBondContact O-N 2.93Å; Q290-Y293 VanDerWaalsContact O-N 3.09Å; Y293-N295 VanDerWaalsContact C-N 3.34Å; Y293-N295 PolarHBondContact O-N 3.14Å; Y293-A296 WeakPolarHBondContact O-CB 3.34Å; Y293-A296 PolarHBondContact O-N 3Å; Y293-A296 VanDerWaalsContact O-N 3.11Å; Y293-I297 WeakPolarHBondContact O-CG1 3.4Å; Y293-I297 PolarHBondContact O-N 3.46Å
294	L	79	Confident	74.3	Confident	28 Å²	28	39.4 Å²	39.4	15%	0.147	20%	0.202	C	C	.	.	H	α-helix	trans	-58.9	-44.6	173.2	-172.2	67.1	0	0	0	112	Q290 P291 A296 I297 Q298 V331	Q290-L294 PolarHBondContact O-N 2.66Å; P291-L294 PolarHBondContact O-N 3.26Å; L294-A296 PolarHBondContact O-N 3.48Å; L294-I297 WeakPolarHBondContact O-CB 3.2Å; L294-I297 PolarHBondContact O-N 3.12Å; L294-I297 VanDerWaalsContact O-N 3.16Å; L294-Q298 WeakPolarHBondContact O-CG 3.42Å; L294-Q298 PolarHBondContact O-N 3.11Å; L294-V331 HydrophobicContact CD1-CG1 3.95Å; L294-V331 HydrophobicContact CD1-CG2 3.94Å; L294-V331 HydrophobicContact CD2-CG2 4.2Å
295	N	78.4	Confident	74.6	Confident	85 Å²	85	39.3 Å²	39.3	46%	0.455	20%	0.202	S	C	.	.	H	α-helix	trans	-61.1	-34.8	176.1	-68.5	-10.8	0	0	0	112.2	P291 Y293 T299	P291-N295 WeakPolarHBondContact O-CB 3.45Å; P291-N295 PolarHBondContact O-N 3.27Å; P291-N295 PolarHBondContact O-ND2 3.01Å; P291-N295 PolarHBondContact O-OD1 3.16Å; Y293-N295 VanDerWaalsContact C-N 3.34Å; Y293-N295 PolarHBondContact O-N 3.14Å; N295-T299 WeakPolarHBondContact O-CB 3.27Å; N295-T299 PolarHBondContact O-N 2.94Å; N295-T299 VanDerWaalsContact O-N 3.11Å; N295-T299 PolarHBondContact O-OG1 3.04Å
296	A	79.3	Confident	74.9	Confident	0 Å²	0	36.1 Å²	36.1	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-68.3	-40.4	176.2	0	0	0	0	0	111.8	L259 I266 Y293 L294 T299 M300	L259-A296 HydrophobicContact CD1-CB 3.62Å; L259-A296 HydrophobicContact CG-CB 4.4Å; I266-A296 HydrophobicContact CD1-CB 4.09Å; Y293-A296 WeakPolarHBondContact O-CB 3.34Å; Y293-A296 PolarHBondContact O-N 3Å; Y293-A296 VanDerWaalsContact O-N 3.11Å; L294-A296 PolarHBondContact O-N 3.48Å; A296-T299 PolarHBondContact O-N 3.39Å; A296-T299 PolarHBondContact O-OG1 3.16Å; A296-M300 PolarHBondContact O-N 3.31Å
297	I	78.5	Confident	75.2	Confident	0 Å²	0	35.7 Å²	35.7	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-60.5	-50.4	174	-65.2	168.5	0	0	0	109.5	I266 F287 Y293 L294 T299 C301 I304 L305 L308	I266-I297 HydrophobicContact CD1-CD1 4.41Å; I266-I297 HydrophobicContact CD1-CG1 3.85Å; F287-I297 HydrophobicContact CB-CD1 4.28Å; F287-I297 HydrophobicContact CD1-CD1 4.42Å; F287-I297 HydrophobicContact CG-CD1 4.38Å; Y293-I297 WeakPolarHBondContact O-CG1 3.4Å; Y293-I297 PolarHBondContact O-N 3.46Å; L294-I297 WeakPolarHBondContact O-CB 3.2Å; L294-I297 PolarHBondContact O-N 3.12Å; L294-I297 VanDerWaalsContact O-N 3.16Å; I297-T299 VanDerWaalsContact C-N 3.3Å; I297-T299 PolarHBondContact O-N 3.49Å; I297-C301 CarbonylContact O-C 3.53Å; I297-C301 PolarHBondContact O-N 3.09Å; I297-C301 VanDerWaalsContact O-N 3.14Å; I297-I304 HydrophobicContact CD1-CG2 4.27Å; I297-I304 HydrophobicContact CG1-CG2 4.45Å; I297-L305 HydrophobicContact CG2-CD2 4.08Å; I297-L305 HydrophobicContact CG2-CG 4.37Å; I297-L308 HydrophobicContact CD1-CD1 4.46Å
298	Q	73.6	Confident	75.6	Confident	59 Å²	59	35.8 Å²	35.8	28%	0.276	18%	0.183	S	C	.	.	H	α-helix	trans	-61.7	-31.4	-178.2	-75.6	179.1	-19.6	0	0	114.4	L294 Q334 E335	L294-Q298 WeakPolarHBondContact O-CG 3.42Å; L294-Q298 PolarHBondContact O-N 3.11Å; Q298-Q334 VanDerWaalsContact NE2-OE1 3.15Å; Q298-E335 WeakPolarHBondContact CA-OE1 3.44Å; Q298-E335 HydrophobicContact CG-CG 4.43Å; Q298-E335 WeakPolarHBondContact CG-OE1 3.24Å
299	T	75.6	Confident	76.1	Confident	93 Å²	93	34.7 Å²	34.7	57%	0.571	18%	0.177	S	C	*	.	H	α-helix	trans	-97.2	-39.3	-174.3	46	0	0	0	0	113.8	N295 A296 I297	N295-T299 WeakPolarHBondContact O-CB 3.27Å; N295-T299 PolarHBondContact O-N 2.94Å; N295-T299 VanDerWaalsContact O-N 3.11Å; N295-T299 PolarHBondContact O-OG1 3.04Å; A296-T299 PolarHBondContact O-N 3.39Å; A296-T299 PolarHBondContact O-OG1 3.16Å; I297-T299 VanDerWaalsContact C-N 3.3Å; I297-T299 PolarHBondContact O-N 3.49Å
300	M	71.6	Confident	76.3	Confident	97 Å²	97	28.5 Å²	28.5	48%	0.478	15%	0.153	S	C	.	.	H	α-helix	trans	-114.9	-30.5	-168.9	-61.4	-64.3	-68.4	0	0	113.4	L259 T263 A296	L259-M300 HydrophobicContact CD2-CG 4.23Å; T263-M300 HydrophobicContact CG2-CB 4.28Å; A296-M300 PolarHBondContact O-N 3.31Å
301	C	64.8	Low	76.4	Confident	1 Å²	1	26.7 Å²	26.7	1%	0.007	15%	0.145	C	C	.	.			trans	-142.5	73.4	-165.8	-66.2	0	0	0	0	113.5	F64 T263 H267 I297 H303 I304	F64-C301 WeakPolarHBondContact CZ-SG 3.33Å; T263-C301 HydrophobicContact CG2-CB 4.35Å; T263-C301 WeakPolarHBondContact CG2-SG 3.35Å; H267-C301 PolarHBondContact CE1-SG 3.43Å; I297-C301 CarbonylContact O-C 3.53Å; I297-C301 PolarHBondContact O-N 3.09Å; I297-C301 VanDerWaalsContact O-N 3.14Å; C301-H303 PolarHBondContact O-N 3.37Å; C301-I304 HydrophobicContact CB-CG1 4.13Å; C301-I304 PolarHBondContact O-N 3.12Å
302	P	75.3	Confident	76.4	Confident	18 Å²	18	22.9 Å²	22.9	12%	0.117	12%	0.12	C	C	.	.	T	Hydrogen-bonded Turn	trans	-70.3	-19.6	-178.5	30.3	-36.7	0	0	0	112.9	I304 L305 T338 Y339	P302-I304 PolarHBondContact O-N 3.03Å; P302-L305 WeakPolarHBondContact O-CB 3.01Å; P302-L305 WeakPolarHBondContact O-CG 3.45Å; P302-L305 PolarHBondContact O-N 2.82Å; P302-T338 HydrophobicContact CB-CG2 4.46Å; P302-T338 HydrophobicContact CG-CG2 4.11Å; P302-Y339 HydrophobicContact CB-CG 4.41Å
303	H	77.9	Confident	76.3	Confident	1 Å²	1	19.1 Å²	19.1	1%	0.005	10%	0.102	C	C	.	.	T	Hydrogen-bonded Turn	trans	-71.1	-16.7	-179.9	57.3	-77.4	0	0	0	114.6	L57 R60 H267 C301 L305 R306 Y339	L57-H303 HydrophobicContact CD2-CB 3.15Å; R60-H303 WeakPolarHBondContact CD-ND1 3.49Å; H267-H303 AromaticContact CD2-NE2 3.85Å; H267-H303 AromaticContact CE1-NE2 3.88Å; H267-H303 AromaticContact NE2-CE1 3.51Å; H267-H303 AromaticContact NE2-NE2 2.9Å; H267-H303 PolarHBondContact NE2-NE2 3.46Å; C301-H303 PolarHBondContact O-N 3.37Å; H303-L305 PolarHBondContact O-N 3.37Å; H303-R306 WeakPolarHBondContact O-CB 3.08Å; H303-R306 PolarHBondContact O-N 3.13Å; H303-Y339 HydrophobicContact CB-CE1 4.43Å; H303-Y339 HydrophobicContact CB-CE2 4.12Å
304	I	79.3	Confident	76.1	Confident	0 Å²	0	19.2 Å²	19.2	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-65.6	-22.3	175.1	-63.6	-61.9	0	0	0	111.4	I266 L270 I297 C301 P302 R306 Y307 L308	I266-I304 HydrophobicContact CG2-CB 4.39Å; I266-I304 HydrophobicContact CG2-CD1 4.16Å; I266-I304 HydrophobicContact CG2-CG1 3.9Å; I266-I304 HydrophobicContact CG2-CG2 3.76Å; L270-I304 HydrophobicContact CD2-CD1 4.26Å; I297-I304 HydrophobicContact CD1-CG2 4.27Å; I297-I304 HydrophobicContact CG1-CG2 4.45Å; C301-I304 HydrophobicContact CB-CG1 4.13Å; C301-I304 PolarHBondContact O-N 3.12Å; P302-I304 PolarHBondContact O-N 3.03Å; I304-R306 PolarHBondContact O-N 3.05Å; I304-Y307 HydrophobicContact CD1-CD2 4.24Å; I304-Y307 PolarHBondContact O-N 2.96Å; I304-L308 WeakPolarHBondContact O-CB 3.5Å; I304-L308 PolarHBondContact O-N 3.37Å
305	L	77.1	Confident	75.7	Confident	4 Å²	4	18.4 Å²	18.4	2%	0.021	10%	0.099	C	C	.	.	H	α-helix	trans	-58.1	-30.2	175.1	-69.6	-170.5	0	0	0	113.4	I297 P302 H303 L308 T309 V331 I332 E335 T344	I297-L305 HydrophobicContact CG2-CD2 4.08Å; I297-L305 HydrophobicContact CG2-CG 4.37Å; P302-L305 WeakPolarHBondContact O-CB 3.01Å; P302-L305 WeakPolarHBondContact O-CG 3.45Å; P302-L305 PolarHBondContact O-N 2.82Å; H303-L305 PolarHBondContact O-N 3.37Å; L305-L308 PolarHBondContact O-N 3.26Å; L305-T309 WeakPolarHBondContact O-CB 3.31Å; L305-T309 WeakPolarHBondContact O-CG2 3.4Å; L305-T309 PolarHBondContact O-N 2.94Å; L305-T309 PolarHBondContact O-OG1 2.98Å; L305-V331 HydrophobicContact CD2-CG1 3.79Å; L305-I332 HydrophobicContact CD1-CG1 4.45Å; L305-E335 HydrophobicContact CD1-CB 3.67Å; L305-E335 VanDerWaalsContact CD1-CD 3.42Å; L305-E335 HydrophobicContact CD1-CG 4.06Å; L305-E335 WeakPolarHBondContact CD1-OE2 3.37Å; L305-E335 WeakPolarHBondContact CG-OE2 3.2Å; L305-T344 HydrophobicContact CB-CG2 4.23Å
306	R	80.2	Confident	75	Confident	0 Å²	0	22.6 Å²	22.6	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-60.6	-45.3	173.2	178.8	179	177	-165.1	-9.4	111.7	H303 I304 T309 T310 D341 I343 V369 D373	H303-R306 WeakPolarHBondContact O-CB 3.08Å; H303-R306 PolarHBondContact O-N 3.13Å; I304-R306 PolarHBondContact O-N 3.05Å; R306-T309 PolarHBondContact O-OG1 3.4Å; R306-T310 WeakPolarHBondContact O-CG2 3.36Å; R306-T310 PolarHBondContact O-N 3.35Å; R306-T310 PolarHBondContact O-OG1 3.34Å; R306-D341 WeakPolarHBondContact CD-OD2 3.4Å; R306-D341 WeakPolarHBondContact CG-OD2 3.38Å; R306-D341 IonicContact NE-OD2 3.33Å; R306-I343 HydrophobicContact CG-CD1 3.77Å; R306-V369 PolarHBondContact NH2-O 3.39Å; R306-D373 IonicContact CZ-OD1 3.07Å; R306-D373 IonicContact CZ-OD2 3.82Å; R306-D373 IonicContact NE-OD2 2.95Å; R306-D373 VanDerWaalsContact NH1-CG 3.29Å; R306-D373 IonicContact NH1-OD1 2.82Å; R306-D373 PolarHBondContact NH1-OD1 3.33Å; R306-D373 IonicContact NH1-OD2 2.63Å; R306-D373 PolarHBondContact NH1-OD2 3Å; R306-D373 VanDerWaalsContact NH1-OD2 3.14Å; R306-D373 IonicContact NH2-OD1 3.72Å; R306-D373 PolarHBondContact NH2-OD1 2.95Å; R306-D373 IonicContact NH2-OD2 3.71Å; R306-D373 PolarHBondContact NH2-OD2 3.02Å
307	Y	78.5	Confident	74.1	Confident	7 Å²	7	26.5 Å²	26.5	3%	0.027	13%	0.134	C	C	.	.	H	α-helix	trans	-75.2	-31.7	179.2	-59.6	-65.6	0	0	0	112.2	I61 L270 F274 I304 T310 A311 D373 F375 L376	I61-Y307 HydrophobicContact CD1-CE2 4.01Å; L270-Y307 HydrophobicContact CD1-CG 4.25Å; L270-Y307 HydrophobicContact CD2-CD1 4.16Å; L270-Y307 HydrophobicContact CD2-CD2 3.45Å; L270-Y307 VanDerWaalsContact CD2-CD2 3.45Å; L270-Y307 HydrophobicContact CD2-CE2 3.88Å; L270-Y307 HydrophobicContact CD2-CG 3.61Å; L270-Y307 HydrophobicContact CG-CG 4.39Å; F274-Y307 AromaticContact CE2-CD1 3.76Å; F274-Y307 HydrophobicContact CE2-CD1 3.76Å; F274-Y307 HydrophobicContact CE2-CG 4.06Å; F274-Y307 AromaticContact CZ-CD1 3.86Å; F274-Y307 HydrophobicContact CZ-CD1 3.86Å; F274-Y307 HydrophobicContact CZ-CG 4.27Å; I304-Y307 HydrophobicContact CD1-CD2 4.24Å; I304-Y307 PolarHBondContact O-N 2.96Å; Y307-T310 WeakPolarHBondContact CA-OG1 3.45Å; Y307-T310 PolarHBondContact O-OG1 3.01Å; Y307-A311 WeakPolarHBondContact O-CB 3.5Å; Y307-A311 PolarHBondContact O-N 2.92Å; Y307-D373 WeakPolarHBondContact CE1-OD2 3.36Å; Y307-D373 PolarHBondContact OH-OD2 2.95Å; Y307-D373 VanDerWaalsContact OH-OD2 3.09Å; Y307-F375 HydrophobicContact CE1-CD2 4.48Å; Y307-L376 HydrophobicContact CD1-CD1 4.22Å; Y307-L376 HydrophobicContact CD1-CD2 4.27Å; Y307-L376 HydrophobicContact CD1-CG 4.27Å; Y307-L376 HydrophobicContact CE1-CD1 4Å; Y307-L376 HydrophobicContact CE1-CG 4.18Å
308	L	77.8	Confident	73.4	Confident	3 Å²	3	30.3 Å²	30.3	2%	0.016	16%	0.157	C	C	.	.	H	α-helix	trans	-69.1	-44	176.8	-164.4	156.3	0	0	0	111.1	F287 L288 I297 I304 L305 A311 V312 L328	F287-L308 HydrophobicContact CB-CD1 3.7Å; F287-L308 HydrophobicContact CD2-CD1 4.23Å; F287-L308 HydrophobicContact CG-CD1 4.36Å; L288-L308 HydrophobicContact CD1-CD1 4.17Å; L288-L308 HydrophobicContact CD1-CD2 3.82Å; I297-L308 HydrophobicContact CD1-CD1 4.46Å; I304-L308 WeakPolarHBondContact O-CB 3.5Å; I304-L308 PolarHBondContact O-N 3.37Å; L305-L308 PolarHBondContact O-N 3.26Å; L308-A311 PolarHBondContact O-N 3.3Å; L308-V312 HydrophobicContact CD2-CG2 3.98Å; L308-V312 WeakPolarHBondContact O-CB 3.42Å; L308-V312 VanDerWaalsContact O-CG2 3.26Å; L308-V312 WeakPolarHBondContact O-CG2 3.47Å; L308-V312 PolarHBondContact O-N 3.1Å; L308-L328 HydrophobicContact CD2-CD1 3.26Å; L308-L328 HydrophobicContact CD2-CD2 4.43Å; L308-L328 HydrophobicContact CD2-CG 4.41Å
309	T	77.3	Confident	72.8	Confident	0 Å²	0	38.1 Å²	38.1	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-60.9	-47.4	175.6	44.5	0	0	0	0	112	L305 R306 V312 I313 L328 I332 I343 V347	L305-T309 WeakPolarHBondContact O-CB 3.31Å; L305-T309 WeakPolarHBondContact O-CG2 3.4Å; L305-T309 PolarHBondContact O-N 2.94Å; L305-T309 PolarHBondContact O-OG1 2.98Å; R306-T309 PolarHBondContact O-OG1 3.4Å; T309-V312 PolarHBondContact O-N 3.41Å; T309-I313 WeakPolarHBondContact O-CB 3.43Å; T309-I313 WeakPolarHBondContact O-CD1 3.47Å; T309-I313 VanDerWaalsContact O-CG1 3.25Å; T309-I313 WeakPolarHBondContact O-CG1 3.43Å; T309-I313 PolarHBondContact O-N 3.2Å; T309-L328 HydrophobicContact CG2-CD1 4.28Å; T309-L328 HydrophobicContact CG2-CD2 4.2Å; T309-I332 HydrophobicContact CG2-CD1 3.45Å; T309-I332 VanDerWaalsContact CG2-CD1 3.45Å; T309-I332 HydrophobicContact CG2-CG1 4.36Å; T309-I343 WeakPolarHBondContact OG1-CG2 3.38Å; T309-V347 HydrophobicContact CG2-CG2 4.21Å
310	T	75.6	Confident	72.2	Confident	0 Å²	0	37.3 Å²	37.3	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-63.3	-42.2	176.5	49.3	0	0	0	0	112.3	R306 Y307 I313 T314 I343 L376 F383	R306-T310 WeakPolarHBondContact O-CG2 3.36Å; R306-T310 PolarHBondContact O-N 3.35Å; R306-T310 PolarHBondContact O-OG1 3.34Å; Y307-T310 WeakPolarHBondContact CA-OG1 3.45Å; Y307-T310 PolarHBondContact O-OG1 3.01Å; T310-I313 PolarHBondContact O-N 2.93Å; T310-T314 WeakPolarHBondContact O-CB 3.28Å; T310-T314 VanDerWaalsContact O-CG2 3.29Å; T310-T314 WeakPolarHBondContact O-CG2 3.27Å; T310-T314 PolarHBondContact O-N 3.39Å; T310-T314 PolarHBondContact O-OG1 3.08Å; T310-I343 HydrophobicContact CG2-CD1 4.11Å; T310-I343 HydrophobicContact CG2-CG2 4.11Å; T310-L376 HydrophobicContact CG2-CD1 4.36Å; T310-L376 HydrophobicContact CG2-CD2 4.03Å; T310-L376 WeakPolarHBondContact OG1-CD2 3.33Å; T310-F383 HydrophobicContact CG2-CD2 4.03Å; T310-F383 HydrophobicContact CG2-CE2 3.88Å; T310-F383 HydrophobicContact CG2-CZ 4.48Å
311	A	75.1	Confident	71.8	Confident	1 Å²	1	33.2 Å²	33.2	1%	0.008	15%	0.152	C	C	.	.	H	α-helix	trans	-65.1	-40.6	176.7	0	0	0	0	0	112.9	I283 Y307 L308 T314 N315	I283-A311 HydrophobicContact CD1-CB 4.03Å; I283-A311 HydrophobicContact CG2-CB 3.9Å; Y307-A311 WeakPolarHBondContact O-CB 3.5Å; Y307-A311 PolarHBondContact O-N 2.92Å; L308-A311 PolarHBondContact O-N 3.3Å; A311-T314 PolarHBondContact O-OG1 3.06Å; A311-N315 PolarHBondContact O-N 2.77Å
312	V	75.5	Confident	71.8	Confident	1 Å²	1	38.9 Å²	38.9	1%	0.006	17%	0.173	C	C	.	.	H	α-helix	trans	-66.9	-42.9	176.6	168.9	0	0	0	0	111.1	I284 L308 T309 N315 R321 V324 L328	I284-V312 HydrophobicContact CD1-CG2 4.25Å; I284-V312 HydrophobicContact CG1-CG2 4.05Å; L308-V312 HydrophobicContact CD2-CG2 3.98Å; L308-V312 WeakPolarHBondContact O-CB 3.42Å; L308-V312 VanDerWaalsContact O-CG2 3.26Å; L308-V312 WeakPolarHBondContact O-CG2 3.47Å; L308-V312 PolarHBondContact O-N 3.1Å; T309-V312 PolarHBondContact O-N 3.41Å; V312-N315 PolarHBondContact O-N 2.77Å; V312-R321 HydrophobicContact CG1-CG 4.48Å; V312-R321 WeakPolarHBondContact O-CG 3.38Å; V312-V324 HydrophobicContact CB-CG1 4.49Å; V312-V324 HydrophobicContact CG1-CG1 3.76Å; V312-V324 HydrophobicContact CG2-CG1 3.83Å; V312-L328 HydrophobicContact CB-CD2 3.94Å; V312-L328 HydrophobicContact CG1-CD2 3.81Å; V312-L328 HydrophobicContact CG2-CD2 4.15Å
313	I	75.1	Confident	71.5	Confident	4 Å²	4	44.4 Å²	44.4	2%	0.021	20%	0.197	C	C	.	.	H	α-helix	trans	-68.7	-35.6	-178.5	-71.2	166.1	0	0	0	111.6	T309 T310 R321 V347 F383 N386	T309-I313 WeakPolarHBondContact O-CB 3.43Å; T309-I313 WeakPolarHBondContact O-CD1 3.47Å; T309-I313 VanDerWaalsContact O-CG1 3.25Å; T309-I313 WeakPolarHBondContact O-CG1 3.43Å; T309-I313 PolarHBondContact O-N 3.2Å; T310-I313 PolarHBondContact O-N 2.93Å; I313-R321 PolarHBondContact O-NE 2.94Å; I313-R321 PolarHBondContact O-NH1 3.06Å; I313-R321 PolarHBondContact O-NH2 3.37Å; I313-V347 HydrophobicContact CD1-CG2 4.02Å; I313-F383 HydrophobicContact CB-CD2 3.98Å; I313-F383 HydrophobicContact CB-CE2 3.95Å; I313-F383 HydrophobicContact CD1-CD2 4.46Å; I313-F383 HydrophobicContact CD1-CE2 3.57Å; I313-F383 HydrophobicContact CD1-CZ 4.21Å; I313-F383 HydrophobicContact CG1-CE2 4.34Å; I313-F383 HydrophobicContact CG2-CD2 3.67Å; I313-F383 HydrophobicContact CG2-CE2 3.83Å; I313-N386 HydrophobicContact CG2-CB 3.79Å; I313-N386 WeakPolarHBondContact O-CB 3.28Å
314	T	73.1	Confident	71.3	Confident	2 Å²	2	44.5 Å²	44.5	1%	0.012	20%	0.198	C	C	.	.	H	α-helix	trans	-81.9	-8.3	-180	54.6	0	0	0	0	114.4	T310 A311 K316 C379 D382 F383	T310-T314 WeakPolarHBondContact O-CB 3.28Å; T310-T314 VanDerWaalsContact O-CG2 3.29Å; T310-T314 WeakPolarHBondContact O-CG2 3.27Å; T310-T314 PolarHBondContact O-N 3.39Å; T310-T314 PolarHBondContact O-OG1 3.08Å; A311-T314 PolarHBondContact O-OG1 3.06Å; T314-K316 PolarHBondContact O-N 3.48Å; T314-C379 HydrophobicContact CG2-CB 4.23Å; T314-D382 HydrophobicContact CG2-CB 4.11Å; T314-F383 HydrophobicContact CG2-CB 3.94Å; T314-F383 HydrophobicContact CG2-CD2 4.47Å
315	N	70.2	Confident	70.9	Confident	10 Å²	10	45 Å²	45	5%	0.053	20%	0.2	C	C	.	.			trans	-67.8	125.2	-178.5	-171.9	-13.5	0	0	0	111.6	D281 I284 A311 V312 D317 R321	D281-N315 PolarHBondContact OD1-ND2 3.49Å; I284-N315 HydrophobicContact CD1-CB 4.14Å; I284-N315 WeakPolarHBondContact CD1-ND2 3.32Å; A311-N315 PolarHBondContact O-N 2.77Å; V312-N315 PolarHBondContact O-N 2.77Å; N315-D317 PolarHBondContact O-N 2.94Å; N315-D317 VanDerWaalsContact O-N 3.15Å; N315-D317 PolarHBondContact OD1-N 3.46Å; N315-R321 PolarHBondContact O-NE 3.12Å; N315-R321 PolarHBondContact O-NH2 2.95Å
316	K	62.9	Low	70.8	Confident	174 Å²	174	52.2 Å²	52.2	76%	0.757	23%	0.231	S	C	*	.	S	Bend	trans	-61	-23.5	-174.8	-60.1	-172.4	178.3	-173.1	0	114.3	T314 V318	T314-K316 PolarHBondContact O-N 3.48Å; K316-V318 PolarHBondContact O-N 3.37Å
317	D	62.3	Low	70.7	Confident	82 Å²	82	55.7 Å²	55.7	44%	0.439	25%	0.25	S	S	.	.			trans	-84.8	95.8	-178	-91.5	-19.3	0	0	0	113.9	N315 R319 K320 R321	N315-D317 PolarHBondContact O-N 2.94Å; N315-D317 VanDerWaalsContact O-N 3.15Å; N315-D317 PolarHBondContact OD1-N 3.46Å; D317-R319 PolarHBondContact O-N 3.38Å; D317-R319 VanDerWaalsContact O-N 3.08Å; D317-K320 HydrophobicContact CB-CB 4.35Å; D317-K320 HydrophobicContact CB-CD 4.46Å; D317-K320 HydrophobicContact CB-CG 4.44Å; D317-K320 PolarHBondContact O-N 2.85Å; D317-R321 WeakPolarHBondContact O-CB 3.44Å; D317-R321 PolarHBondContact O-N 3.14Å; D317-R321 VanDerWaalsContact O-N 3.07Å
318	V	62.3	Low	70.8	Confident	80 Å²	80	55.3 Å²	55.3	49%	0.485	25%	0.249	S	C	.	.	H	α-helix	trans	-53.7	-31.4	178.2	-177.6	0	0	0	0	113.4	K316 R322	K316-V318 PolarHBondContact O-N 3.37Å; V318-R322 PolarHBondContact O-N 2.83Å
319	R	62.2	Low	70.9	Confident	222 Å²	222	56 Å²	56	84%	0.838	25%	0.253	S	S	*	.	H	α-helix	trans	-73.4	-49.3	-178.7	-82.1	-173.7	-89.4	-168.9	-5.4	113.3	D317 R321 R322	D317-R319 PolarHBondContact O-N 3.38Å; D317-R319 VanDerWaalsContact O-N 3.08Å; R319-R321 VanDerWaalsContact C-N 3.26Å; R319-R321 PolarHBondContact O-N 3.17Å; R319-R322 PolarHBondContact O-N 2.81Å
320	K	62.3	Low	71	Confident	76 Å²	76	61.4 Å²	61.4	33%	0.33	28%	0.277	S	S	.	.	H	α-helix	trans	-62	-40.7	174.5	-71.1	-175.2	-179.2	179	0	110.1	D281 D317 R322 Q323 V324	D281-K320 IonicContact OD1-NZ 3.61Å; D281-K320 IonicContact OD2-NZ 2.88Å; D317-K320 HydrophobicContact CB-CB 4.35Å; D317-K320 HydrophobicContact CB-CD 4.46Å; D317-K320 HydrophobicContact CB-CG 4.44Å; D317-K320 PolarHBondContact O-N 2.85Å; K320-R322 PolarHBondContact O-N 3.31Å; K320-Q323 PolarHBondContact O-N 3.33Å; K320-V324 WeakPolarHBondContact O-CB 3.42Å; K320-V324 VanDerWaalsContact O-CG2 3.3Å; K320-V324 WeakPolarHBondContact O-CG2 3.48Å; K320-V324 PolarHBondContact O-N 3.48Å
321	R	62.9	Low	71.2	Confident	11 Å²	11	62 Å²	62	4%	0.042	28%	0.28	C	S	.	.	H	α-helix	trans	-53.1	-47.5	178.1	-147.6	-171.6	-79.8	-175.7	-4.8	112.9	V312 I313 N315 D317 R319 Q323 V324 L325 N386 F390	V312-R321 HydrophobicContact CG1-CG 4.48Å; V312-R321 WeakPolarHBondContact O-CG 3.38Å; I313-R321 PolarHBondContact O-NE 2.94Å; I313-R321 PolarHBondContact O-NH1 3.06Å; I313-R321 PolarHBondContact O-NH2 3.37Å; N315-R321 PolarHBondContact O-NE 3.12Å; N315-R321 PolarHBondContact O-NH2 2.95Å; D317-R321 WeakPolarHBondContact O-CB 3.44Å; D317-R321 PolarHBondContact O-N 3.14Å; D317-R321 VanDerWaalsContact O-N 3.07Å; R319-R321 VanDerWaalsContact C-N 3.26Å; R319-R321 PolarHBondContact O-N 3.17Å; R321-Q323 PolarHBondContact O-N 2.95Å; R321-V324 PolarHBondContact O-N 3.24Å; R321-L325 HydrophobicContact CG-CD1 4.09Å; R321-L325 VanDerWaalsContact O-CB 3.22Å; R321-L325 WeakPolarHBondContact O-CB 3.31Å; R321-L325 VanDerWaalsContact O-CD1 3.31Å; R321-L325 WeakPolarHBondContact O-CD1 3.31Å; R321-L325 WeakPolarHBondContact O-CG 3.45Å; R321-L325 PolarHBondContact O-N 2.93Å; R321-N386 PolarHBondContact NH1-OD1 3.37Å; R321-N386 PolarHBondContact NH2-OD1 3.18Å; R321-F390 VanDerWaalsContact CD-CE2 3.48Å; R321-F390 HydrophobicContact CG-CE2 4.46Å; R321-F390 HydrophobicContact CG-CZ 3.94Å
322	R	65.3	Low	71.4	Confident	120 Å²	120	62.3 Å²	62.3	45%	0.453	28%	0.282	S	S	.	.	H	α-helix	trans	-65.6	-31.2	-179.1	-78.3	-176.5	-178.5	172.7	3.5	114.5	V318 R319 K320 E393	V318-R322 PolarHBondContact O-N 2.83Å; R319-R322 PolarHBondContact O-N 2.81Å; K320-R322 PolarHBondContact O-N 3.31Å; R322-E393 IonicContact CZ-OE1 3.27Å; R322-E393 IonicContact NE-OE1 3.46Å; R322-E393 IonicContact NH2-OE1 3.71Å; R322-E393 PolarHBondContact NH2-OE1 3.44Å
323	Q	69.2	Low	71.5	Confident	135 Å²	135	66.3 Å²	66.3	63%	0.631	30%	0.3	S	S	*	.	H	α-helix	trans	-76.5	-49.4	177.1	-69	175.6	-13.7	0	0	110.1	K320 R321 L325 K326	K320-Q323 PolarHBondContact O-N 3.33Å; R321-Q323 PolarHBondContact O-N 2.95Å; Q323-L325 VanDerWaalsContact C-N 3.33Å; Q323-L325 PolarHBondContact O-N 3.4Å; Q323-K326 PolarHBondContact O-N 2.74Å
324	V	72.6	Confident	71.5	Confident	2 Å²	2	71.6 Å²	71.6	1%	0.012	33%	0.325	C	S	.	.	H	α-helix	trans	-62.2	-37.7	-179.5	164	0	0	0	0	112.4	I284 L288 V312 K320 R321 K326 D327 L328	I284-V324 HydrophobicContact CG2-CB 4.49Å; I284-V324 HydrophobicContact CG2-CG1 4.1Å; I284-V324 HydrophobicContact CG2-CG2 3.62Å; L288-V324 HydrophobicContact CD2-CB 4.18Å; L288-V324 HydrophobicContact CD2-CG1 3.56Å; L288-V324 HydrophobicContact CD2-CG2 4.24Å; V312-V324 HydrophobicContact CB-CG1 4.49Å; V312-V324 HydrophobicContact CG1-CG1 3.76Å; V312-V324 HydrophobicContact CG2-CG1 3.83Å; K320-V324 WeakPolarHBondContact O-CB 3.42Å; K320-V324 VanDerWaalsContact O-CG2 3.3Å; K320-V324 WeakPolarHBondContact O-CG2 3.48Å; K320-V324 PolarHBondContact O-N 3.48Å; R321-V324 PolarHBondContact O-N 3.24Å; V324-K326 VanDerWaalsContact C-N 3.27Å; V324-K326 PolarHBondContact O-N 3.12Å; V324-D327 PolarHBondContact O-N 2.91Å; V324-L328 WeakPolarHBondContact O-CB 3.46Å; V324-L328 PolarHBondContact O-N 2.89Å
325	L	71.1	Confident	71.4	Confident	10 Å²	10	72 Å²	72	5%	0.052	33%	0.326	C	S	.	.	H	α-helix	trans	-57.2	-36.7	179.7	-90.4	161.1	0	0	0	113.4	R321 Q323 V329 Y351 F390	R321-L325 HydrophobicContact CG-CD1 4.09Å; R321-L325 VanDerWaalsContact O-CB 3.22Å; R321-L325 WeakPolarHBondContact O-CB 3.31Å; R321-L325 VanDerWaalsContact O-CD1 3.31Å; R321-L325 WeakPolarHBondContact O-CD1 3.31Å; R321-L325 WeakPolarHBondContact O-CG 3.45Å; R321-L325 PolarHBondContact O-N 2.93Å; Q323-L325 VanDerWaalsContact C-N 3.33Å; Q323-L325 PolarHBondContact O-N 3.4Å; L325-V329 WeakPolarHBondContact O-CG2 3.39Å; L325-V329 PolarHBondContact O-N 3.46Å; L325-Y351 HydrophobicContact CD2-CE2 3.74Å; L325-F390 HydrophobicContact CD1-CE1 3.88Å; L325-F390 HydrophobicContact CD1-CE2 4.24Å; L325-F390 HydrophobicContact CD1-CZ 3.47Å; L325-F390 VanDerWaalsContact CD1-CZ 3.47Å
326	K	75.3	Confident	71.2	Confident	156 Å²	156	73.1 Å²	73.1	68%	0.678	34%	0.335	S	S	*	.	H	α-helix	trans	-67.5	-39.8	179.9	-71.2	-173.8	177.6	-175.9	0	112	Q323 V324 K330	Q323-K326 PolarHBondContact O-N 2.74Å; V324-K326 VanDerWaalsContact C-N 3.27Å; V324-K326 PolarHBondContact O-N 3.12Å; K326-K330 WeakPolarHBondContact O-CG 3.44Å; K326-K330 PolarHBondContact O-N 3.11Å
327	D	78.2	Confident	71.6	Confident	73 Å²	73	73.8 Å²	73.8	39%	0.39	33%	0.334	S	S	.	.	H	α-helix	trans	-78.8	-34.4	179.9	-64.1	-32.8	0	0	0	110.9	L288 V324 V329 K330 V331	L288-D327 HydrophobicContact CD2-CB 4.42Å; V324-D327 PolarHBondContact O-N 2.91Å; D327-V329 PolarHBondContact O-N 3.36Å; D327-K330 WeakPolarHBondContact O-CB 3.47Å; D327-K330 PolarHBondContact O-N 3.44Å; D327-K330 IonicContact OD1-NZ 3.73Å; D327-K330 PolarHBondContact OD1-NZ 3.45Å; D327-V331 WeakPolarHBondContact O-CG2 3.24Å; D327-V331 PolarHBondContact O-N 3.29Å
328	L	79.8	Confident	72	Confident	0 Å²	0	73.6 Å²	73.6	0%	0	34%	0.336	C	S	.	.	H	α-helix	trans	-57.6	-48.8	170.1	177.4	57.3	0	0	0	112.3	L308 T309 V312 V324 K330 V331 I332	L308-L328 HydrophobicContact CD2-CD1 3.26Å; L308-L328 HydrophobicContact CD2-CD2 4.43Å; L308-L328 HydrophobicContact CD2-CG 4.41Å; T309-L328 HydrophobicContact CG2-CD1 4.28Å; T309-L328 HydrophobicContact CG2-CD2 4.2Å; V312-L328 HydrophobicContact CB-CD2 3.94Å; V312-L328 HydrophobicContact CG1-CD2 3.81Å; V312-L328 HydrophobicContact CG2-CD2 4.15Å; V324-L328 WeakPolarHBondContact O-CB 3.46Å; V324-L328 PolarHBondContact O-N 2.89Å; L328-K330 VanDerWaalsContact C-N 3.26Å; L328-K330 PolarHBondContact O-N 2.92Å; L328-V331 PolarHBondContact O-N 3.49Å; L328-V331 VanDerWaalsContact O-N 3.14Å; L328-I332 HydrophobicContact CD1-CD1 3.77Å; L328-I332 HydrophobicContact CD1-CG1 4.05Å; L328-I332 HydrophobicContact CD2-CD1 4.42Å; L328-I332 HydrophobicContact CG-CD1 3.73Å; L328-I332 HydrophobicContact CG-CG1 4.42Å; L328-I332 WeakPolarHBondContact O-CG1 3.32Å; L328-I332 PolarHBondContact O-N 3.27Å
329	V	80.8	Confident	72.3	Confident	18 Å²	18	71.2 Å²	71.2	11%	0.109	32%	0.319	C	S	.	.	H	α-helix	trans	-61	-37.2	179.2	171.3	0	0	0	0	111	L325 D327 I332 Q333 V347 Y351 V352	L325-V329 WeakPolarHBondContact O-CG2 3.39Å; L325-V329 PolarHBondContact O-N 3.46Å; D327-V329 PolarHBondContact O-N 3.36Å; V329-I332 PolarHBondContact O-N 3.38Å; V329-Q333 HydrophobicContact CG1-CG 4.39Å; V329-Q333 WeakPolarHBondContact O-CB 3.2Å; V329-Q333 VanDerWaalsContact O-CG 3.29Å; V329-Q333 WeakPolarHBondContact O-CG 3.34Å; V329-Q333 PolarHBondContact O-N 3.11Å; V329-V347 HydrophobicContact CG2-CG1 4.03Å; V329-Y351 HydrophobicContact CG2-CD2 3.75Å; V329-Y351 HydrophobicContact CG2-CG 3.85Å; V329-V352 HydrophobicContact CG1-CG2 4.24Å
330	K	79.6	Confident	72.3	Confident	113 Å²	113	68 Å²	68	49%	0.491	31%	0.311	S	S	.	.	H	α-helix	trans	-64.2	-42.8	174.9	-69.3	172.3	-168.3	158	0	112.3	K326 D327 L328 Q333 Q334	K326-K330 WeakPolarHBondContact O-CG 3.44Å; K326-K330 PolarHBondContact O-N 3.11Å; D327-K330 WeakPolarHBondContact O-CB 3.47Å; D327-K330 PolarHBondContact O-N 3.44Å; D327-K330 IonicContact OD1-NZ 3.73Å; D327-K330 PolarHBondContact OD1-NZ 3.45Å; L328-K330 VanDerWaalsContact C-N 3.26Å; L328-K330 PolarHBondContact O-N 2.92Å; K330-Q333 PolarHBondContact O-N 3.18Å; K330-Q334 VanDerWaalsContact O-CG 3.3Å; K330-Q334 WeakPolarHBondContact O-CG 3.4Å; K330-Q334 PolarHBondContact O-N 3.26Å
331	V	79.4	Confident	72.8	Confident	13 Å²	13	64.4 Å²	64.4	8%	0.079	30%	0.295	C	S	.	.	H	α-helix	trans	-63.9	-44.7	177.7	174.7	0	0	0	0	110.3	L294 L305 D327 L328 Q333 Q334 E335	L294-V331 HydrophobicContact CD1-CG1 3.95Å; L294-V331 HydrophobicContact CD1-CG2 3.94Å; L294-V331 HydrophobicContact CD2-CG2 4.2Å; L305-V331 HydrophobicContact CD2-CG1 3.79Å; D327-V331 WeakPolarHBondContact O-CG2 3.24Å; D327-V331 PolarHBondContact O-N 3.29Å; L328-V331 PolarHBondContact O-N 3.49Å; L328-V331 VanDerWaalsContact O-N 3.14Å; V331-Q333 PolarHBondContact O-N 2.89Å; V331-Q334 WeakPolarHBondContact O-CB 3.43Å; V331-Q334 PolarHBondContact O-N 3.09Å; V331-E335 PolarHBondContact O-N 3.07Å
332	I	79.1	Confident	73.5	Confident	7 Å²	7	63.9 Å²	63.9	4%	0.036	29%	0.293	C	S	.	.	H	α-helix	trans	-62.7	-43.4	177.4	-66.1	167.3	0	0	0	111.1	L305 T309 L328 V329 Q334 E335 S336 V347	L305-I332 HydrophobicContact CD1-CG1 4.45Å; T309-I332 HydrophobicContact CG2-CD1 3.45Å; T309-I332 VanDerWaalsContact CG2-CD1 3.45Å; T309-I332 HydrophobicContact CG2-CG1 4.36Å; L328-I332 HydrophobicContact CD1-CD1 3.77Å; L328-I332 HydrophobicContact CD1-CG1 4.05Å; L328-I332 HydrophobicContact CD2-CD1 4.42Å; L328-I332 HydrophobicContact CG-CD1 3.73Å; L328-I332 HydrophobicContact CG-CG1 4.42Å; L328-I332 WeakPolarHBondContact O-CG1 3.32Å; L328-I332 PolarHBondContact O-N 3.27Å; V329-I332 PolarHBondContact O-N 3.38Å; I332-Q334 VanDerWaalsContact C-N 3.29Å; I332-Q334 PolarHBondContact O-N 3.27Å; I332-E335 CarbonylContact O-C 3.58Å; I332-E335 PolarHBondContact O-N 3.46Å; I332-E335 VanDerWaalsContact O-N 3.13Å; I332-S336 PolarHBondContact O-N 3.3Å; I332-V347 HydrophobicContact CD1-CB 4.15Å; I332-V347 HydrophobicContact CD1-CG1 3.77Å
333	Q	77.1	Confident	74.1	Confident	85 Å²	85	58.1 Å²	58.1	40%	0.397	27%	0.271	S	S	.	.	H	α-helix	trans	-59.9	-41.5	175.9	-80	178.7	-14	0	0	111.9	V329 K330 V331 E335 S336 V352	V329-Q333 HydrophobicContact CG1-CG 4.39Å; V329-Q333 WeakPolarHBondContact O-CB 3.2Å; V329-Q333 VanDerWaalsContact O-CG 3.29Å; V329-Q333 WeakPolarHBondContact O-CG 3.34Å; V329-Q333 PolarHBondContact O-N 3.11Å; K330-Q333 PolarHBondContact O-N 3.18Å; V331-Q333 PolarHBondContact O-N 2.89Å; Q333-E335 VanDerWaalsContact C-N 3.29Å; Q333-E335 PolarHBondContact O-N 3.19Å; Q333-S336 PolarHBondContact O-OG 3.35Å; Q333-V352 HydrophobicContact CG-CG2 4.07Å
334	Q	76.9	Confident	74.5	Confident	115 Å²	115	52.1 Å²	52.1	54%	0.537	24%	0.244	S	C	.	.	H	α-helix	trans	-64.1	-33.9	176.4	-73.6	174.3	-2.4	0	0	112.1	Q298 K330 V331 I332 Y337	Q298-Q334 VanDerWaalsContact NE2-OE1 3.15Å; K330-Q334 VanDerWaalsContact O-CG 3.3Å; K330-Q334 WeakPolarHBondContact O-CG 3.4Å; K330-Q334 PolarHBondContact O-N 3.26Å; V331-Q334 WeakPolarHBondContact O-CB 3.43Å; V331-Q334 PolarHBondContact O-N 3.09Å; I332-Q334 VanDerWaalsContact C-N 3.29Å; I332-Q334 PolarHBondContact O-N 3.27Å; Q334-Y337 WeakPolarHBondContact O-CD1 3.49Å; Q334-Y337 WeakPolarHBondContact O-CE1 3.35Å
335	E	70.4	Confident	74.8	Confident	9 Å²	9	55 Å²	55	4%	0.042	26%	0.257	C	S	.	.	H	α-helix	trans	-97.8	-1.9	-176.7	-68.2	-172.9	-149.1	0	0	114.8	Q298 L305 V331 I332 Q333 Y337 T338 Y339	Q298-E335 WeakPolarHBondContact CA-OE1 3.44Å; Q298-E335 HydrophobicContact CG-CG 4.43Å; Q298-E335 WeakPolarHBondContact CG-OE1 3.24Å; L305-E335 HydrophobicContact CD1-CB 3.67Å; L305-E335 VanDerWaalsContact CD1-CD 3.42Å; L305-E335 HydrophobicContact CD1-CG 4.06Å; L305-E335 WeakPolarHBondContact CD1-OE2 3.37Å; L305-E335 WeakPolarHBondContact CG-OE2 3.2Å; V331-E335 PolarHBondContact O-N 3.07Å; I332-E335 CarbonylContact O-C 3.58Å; I332-E335 PolarHBondContact O-N 3.46Å; I332-E335 VanDerWaalsContact O-N 3.13Å; Q333-E335 VanDerWaalsContact C-N 3.29Å; Q333-E335 PolarHBondContact O-N 3.19Å; E335-Y337 PolarHBondContact O-N 3.43Å; E335-T338 PolarHBondContact O-N 3.01Å; E335-Y339 PolarHBondContact O-N 2.9Å
336	S	66.3	Low	75.4	Confident	34 Å²	34	54.7 Å²	54.7	24%	0.238	26%	0.256	C	S	.	.	T	Hydrogen-bonded Turn	trans	-56.4	-19.1	-179.7	63.1	0	0	0	0	114.7	I332 Q333	I332-S336 PolarHBondContact O-N 3.3Å; Q333-S336 PolarHBondContact O-OG 3.35Å
337	Y	71.5	Confident	75.6	Confident	188 Å²	188	47.4 Å²	47.4	74%	0.737	22%	0.224	S	C	*	.	T	Hydrogen-bonded Turn	trans	-82.5	-26.5	177.9	74.9	-87.1	0	0	0	113.7	Q334 E335	Q334-Y337 WeakPolarHBondContact O-CD1 3.49Å; Q334-Y337 WeakPolarHBondContact O-CE1 3.35Å; E335-Y337 PolarHBondContact O-N 3.43Å
338	T	69.6	Low	75.8	Confident	78 Å²	78	46.4 Å²	46.4	48%	0.479	22%	0.217	S	C	.	.	T	Hydrogen-bonded Turn	trans	-98.2	-37.4	-172.6	-50.6	0	0	0	0	112.3	P302 E335	P302-T338 HydrophobicContact CB-CG2 4.46Å; P302-T338 HydrophobicContact CG-CG2 4.11Å; E335-T338 PolarHBondContact O-N 3.01Å
339	Y	68.1	Low	75.6	Confident	30 Å²	30	47 Å²	47	12%	0.118	22%	0.221	C	C	.	.			trans	-138.5	127.8	-172.6	-173.1	-106.1	0	0	0	111	P302 H303 E335 D341	P302-Y339 HydrophobicContact CB-CG 4.41Å; H303-Y339 HydrophobicContact CB-CE1 4.43Å; H303-Y339 HydrophobicContact CB-CE2 4.12Å; E335-Y339 PolarHBondContact O-N 2.9Å; Y339-D341 HydrophobicContact CD1-CB 4.23Å; Y339-D341 HydrophobicContact CE1-CB 3.46Å; Y339-D341 VanDerWaalsContact CE1-CB 3.46Å
340	K	63.4	Low	75.6	Confident	155 Å²	155	46.3 Å²	46.3	67%	0.674	22%	0.217	S	C	*	.			trans	-123.7	117.6	177.2	-66.9	-167.2	176.2	-165.9	0	109.2
341	D	73.3	Confident	75.5	Confident	0 Å²	0	43.6 Å²	43.6	0%	0	20%	0.204	C	C	.	.			trans	-130.5	145.8	177	-175.5	50.5	0	0	0	108.9	R306 Y339 I343 T344 E345	R306-D341 WeakPolarHBondContact CD-OD2 3.4Å; R306-D341 WeakPolarHBondContact CG-OD2 3.38Å; R306-D341 IonicContact NE-OD2 3.33Å; Y339-D341 HydrophobicContact CD1-CB 4.23Å; Y339-D341 HydrophobicContact CE1-CB 3.46Å; Y339-D341 VanDerWaalsContact CE1-CB 3.46Å; D341-I343 PolarHBondContact O-N 3.04Å; D341-T344 HydrophobicContact CB-CG2 4.36Å; D341-T344 PolarHBondContact N-OG1 3.36Å; D341-T344 PolarHBondContact O-N 3.15Å; D341-T344 VanDerWaalsContact O-N 3.08Å; D341-T344 PolarHBondContact O-OG1 2.94Å; D341-E345 VanDerWaalsContact O-CB 3.27Å; D341-E345 WeakPolarHBondContact O-CB 3.41Å; D341-E345 PolarHBondContact O-N 3.14Å
342	P	76.5	Confident	75.5	Confident	0 Å²	0	45.5 Å²	45.5	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-56	-28.9	-179	-29.6	38.3	0	0	0	113.2	Y55 F346 K362 E365 C366 V369	Y55-P342 VanDerWaalsContact CE1-CD 3.42Å; Y55-P342 HydrophobicContact CE1-CG 3.94Å; Y55-P342 HydrophobicContact CE2-CG 4.37Å; P342-F346 WeakPolarHBondContact O-CB 3.41Å; P342-F346 PolarHBondContact O-N 2.95Å; P342-K362 HydrophobicContact CB-CD 4.47Å; P342-E365 HydrophobicContact CB-CB 4.19Å; P342-C366 VanDerWaalsContact C-SG 3.53Å; P342-C366 PolarHBondContact O-SG 3.36Å; P342-V369 HydrophobicContact CG-CG2 4.47Å
343	I	77.8	Confident	75.4	Confident	0 Å²	0	50 Å²	50	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-75.5	-43.8	177.9	-62.7	164.5	0	0	0	111.5	R306 T309 T310 D341 E345 F346 V347 C366 L370 F383	R306-I343 HydrophobicContact CG-CD1 3.77Å; T309-I343 WeakPolarHBondContact OG1-CG2 3.38Å; T310-I343 HydrophobicContact CG2-CD1 4.11Å; T310-I343 HydrophobicContact CG2-CG2 4.11Å; D341-I343 PolarHBondContact O-N 3.04Å; I343-E345 VanDerWaalsContact C-N 3.34Å; I343-F346 WeakPolarHBondContact O-CB 3.39Å; I343-F346 PolarHBondContact O-N 2.94Å; I343-V347 PolarHBondContact O-N 2.99Å; I343-C366 HydrophobicContact CG1-CB 4.14Å; I343-C366 VanDerWaalsContact CG1-SG 3.53Å; I343-L370 HydrophobicContact CD1-CD1 3.83Å; I343-L370 HydrophobicContact CD1-CG 4.4Å; I343-L370 HydrophobicContact CG1-CD1 4.25Å; I343-F383 HydrophobicContact CG2-CZ 4.14Å
344	T	77.3	Confident	75.4	Confident	8 Å²	8	50.7 Å²	50.7	5%	0.049	24%	0.242	C	C	.	.	H	α-helix	trans	-68.7	-38.7	176.6	58.7	0	0	0	0	110.8	L305 D341 F346 V347 E348	L305-T344 HydrophobicContact CB-CG2 4.23Å; D341-T344 HydrophobicContact CB-CG2 4.36Å; D341-T344 PolarHBondContact N-OG1 3.36Å; D341-T344 PolarHBondContact O-N 3.15Å; D341-T344 VanDerWaalsContact O-N 3.08Å; D341-T344 PolarHBondContact O-OG1 2.94Å; T344-F346 VanDerWaalsContact C-N 3.35Å; T344-V347 PolarHBondContact O-N 3.44Å; T344-E348 PolarHBondContact O-N 3.31Å
345	E	80.2	Confident	75.5	Confident	64 Å²	64	49 Å²	49	30%	0.299	24%	0.236	S	C	.	.	H	α-helix	trans	-66.5	-35.8	175.8	-168.5	174.5	-168.5	0	0	111.5	D341 I343 V347 E348 C349 K362	D341-E345 VanDerWaalsContact O-CB 3.27Å; D341-E345 WeakPolarHBondContact O-CB 3.41Å; D341-E345 PolarHBondContact O-N 3.14Å; I343-E345 VanDerWaalsContact C-N 3.34Å; E345-V347 VanDerWaalsContact C-N 3.34Å; E345-V347 PolarHBondContact O-N 2.77Å; E345-E348 PolarHBondContact O-N 3.14Å; E345-C349 WeakPolarHBondContact O-CB 3.49Å; E345-C349 PolarHBondContact O-N 3.33Å; E345-C349 PolarHBondContact O-SG 3.42Å; E345-C349 VanDerWaalsContact O-SG 3.38Å; E345-K362 HydrophobicContact CB-CD 4.45Å; E345-K362 VanDerWaalsContact CD-CE 3.42Å; E345-K362 HydrophobicContact CG-CD 4.22Å; E345-K362 IonicContact OE1-NZ 2.71Å; E345-K362 WeakPolarHBondContact OE2-CE 3.3Å; E345-K362 IonicContact OE2-NZ 2.95Å; E345-K362 PolarHBondContact OE2-NZ 3.49Å
346	F	82	Confident	75.7	Confident	3 Å²	3	50.1 Å²	50.1	1%	0.013	24%	0.241	C	C	.	.	H	α-helix	trans	-57.5	-46.3	172	170.1	-101.6	0	0	0	112	P342 I343 T344 L350 A359 K362 L363 A387 I391	P342-F346 WeakPolarHBondContact O-CB 3.41Å; P342-F346 PolarHBondContact O-N 2.95Å; I343-F346 WeakPolarHBondContact O-CB 3.39Å; I343-F346 PolarHBondContact O-N 2.94Å; T344-F346 VanDerWaalsContact C-N 3.35Å; F346-L350 HydrophobicContact CE1-CD2 4.41Å; F346-L350 HydrophobicContact CZ-CD2 4.29Å; F346-L350 WeakPolarHBondContact O-CB 3.22Å; F346-L350 PolarHBondContact O-N 3.36Å; F346-A359 HydrophobicContact CD2-CB 4Å; F346-A359 VanDerWaalsContact CD2-O 3.3Å; F346-A359 WeakPolarHBondContact CD2-O 3.46Å; F346-A359 HydrophobicContact CE2-CB 3.88Å; F346-K362 HydrophobicContact CB-CB 4.24Å; F346-K362 HydrophobicContact CD2-CB 4.49Å; F346-L363 HydrophobicContact CE2-CB 4.44Å; F346-L363 HydrophobicContact CE2-CD1 4.37Å; F346-A387 HydrophobicContact CE1-CB 4Å; F346-A387 HydrophobicContact CZ-CB 3.95Å; F346-I391 HydrophobicContact CE2-CD1 3.63Å; F346-I391 HydrophobicContact CE2-CG1 3.99Å; F346-I391 HydrophobicContact CZ-CD1 3.71Å; F346-I391 HydrophobicContact CZ-CG1 3.77Å
347	V	81.3	Confident	76.2	Confident	3 Å²	3	52.1 Å²	52.1	2%	0.018	25%	0.249	C	C	.	.	H	α-helix	trans	-67.2	-38.7	178.3	178.4	0	0	0	0	111	T309 I313 V329 I332 I343 T344 E345 L350 Y351	T309-V347 HydrophobicContact CG2-CG2 4.21Å; I313-V347 HydrophobicContact CD1-CG2 4.02Å; V329-V347 HydrophobicContact CG2-CG1 4.03Å; I332-V347 HydrophobicContact CD1-CB 4.15Å; I332-V347 HydrophobicContact CD1-CG1 3.77Å; I343-V347 PolarHBondContact O-N 2.99Å; T344-V347 PolarHBondContact O-N 3.44Å; E345-V347 VanDerWaalsContact C-N 3.34Å; E345-V347 PolarHBondContact O-N 2.77Å; V347-L350 PolarHBondContact O-N 2.94Å; V347-Y351 HydrophobicContact CG1-CD2 3.92Å; V347-Y351 HydrophobicContact CG1-CE2 4.44Å; V347-Y351 PolarHBondContact O-N 2.84Å
348	E	80.6	Confident	76.5	Confident	51 Å²	51	44 Å²	44	24%	0.238	22%	0.222	C	C	.	.	H	α-helix	trans	-64	-48.1	176	-168.9	177	-177.4	0	0	111.8	T344 E345 L350 V352 N353	T344-E348 PolarHBondContact O-N 3.31Å; E345-E348 PolarHBondContact O-N 3.14Å; E348-L350 VanDerWaalsContact C-N 3.28Å; E348-L350 PolarHBondContact O-N 3.32Å; E348-V352 HydrophobicContact CG-CB 4.29Å; E348-V352 HydrophobicContact CG-CG2 3.99Å; E348-V352 WeakPolarHBondContact O-CA 3.4Å; E348-V352 WeakPolarHBondContact O-CB 3.2Å; E348-V352 WeakPolarHBondContact O-CG2 3.26Å; E348-V352 PolarHBondContact O-N 3.16Å; E348-N353 PolarHBondContact O-N 3.03Å
349	C	77.2	Confident	76.9	Confident	14 Å²	14	40.3 Å²	40.3	10%	0.095	20%	0.199	C	C	.	.	I	π-helix	trans	-59	-39	174.7	-76	0	0	0	0	112.2	E345 F354 D355 A359	E345-C349 WeakPolarHBondContact O-CB 3.49Å; E345-C349 PolarHBondContact O-N 3.33Å; E345-C349 PolarHBondContact O-SG 3.42Å; E345-C349 VanDerWaalsContact O-SG 3.38Å; C349-F354 WeakPolarHBondContact O-CA 3.28Å; C349-F354 PolarHBondContact O-N 3.49Å; C349-D355 PolarHBondContact O-N 3.42Å; C349-D355 VanDerWaalsContact O-N 3.13Å; C349-A359 HydrophobicContact CB-CB 4.42Å
350	L	80.4	Confident	77.2	Confident	3 Å²	3	40.6 Å²	40.6	2%	0.016	20%	0.202	C	C	.	.	I	π-helix	trans	-74.1	-41.8	-177	-175	62.5	0	0	0	113.3	F346 V347 E348 F354 F356 F390 I391	F346-L350 HydrophobicContact CE1-CD2 4.41Å; F346-L350 HydrophobicContact CZ-CD2 4.29Å; F346-L350 WeakPolarHBondContact O-CB 3.22Å; F346-L350 PolarHBondContact O-N 3.36Å; V347-L350 PolarHBondContact O-N 2.94Å; E348-L350 VanDerWaalsContact C-N 3.28Å; E348-L350 PolarHBondContact O-N 3.32Å; L350-F354 WeakPolarHBondContact O-CD1 3.47Å; L350-F356 HydrophobicContact CD1-CD1 4.4Å; L350-F356 HydrophobicContact CD1-CE1 4.1Å; L350-F390 HydrophobicContact CD2-CB 4.18Å; L350-I391 HydrophobicContact CD1-CG1 4.16Å; L350-I391 HydrophobicContact CD2-CG1 4.48Å
351	Y	77.1	Confident	78.1	Confident	55 Å²	55	39 Å²	39	22%	0.216	20%	0.195	C	C	.	.	I	π-helix	trans	-104.2	-19	-172.3	-74	-69.8	0	0	0	115.3	L325 V329 V347 F354	L325-Y351 HydrophobicContact CD2-CE2 3.74Å; V329-Y351 HydrophobicContact CG2-CD2 3.75Å; V329-Y351 HydrophobicContact CG2-CG 3.85Å; V347-Y351 HydrophobicContact CG1-CD2 3.92Å; V347-Y351 HydrophobicContact CG1-CE2 4.44Å; V347-Y351 PolarHBondContact O-N 2.84Å; Y351-F354 WeakPolarHBondContact O-CE2 2.87Å
352	V	79.8	Confident	78.5	Confident	53 Å²	53	40.8 Å²	40.8	32%	0.321	20%	0.203	S	C	.	.	I	π-helix	trans	-104.4	-55.4	-179.1	-169.6	0	0	0	0	110.3	V329 Q333 E348	V329-V352 HydrophobicContact CG1-CG2 4.24Å; Q333-V352 HydrophobicContact CG-CG2 4.07Å; E348-V352 HydrophobicContact CG-CB 4.29Å; E348-V352 HydrophobicContact CG-CG2 3.99Å; E348-V352 WeakPolarHBondContact O-CA 3.4Å; E348-V352 WeakPolarHBondContact O-CB 3.2Å; E348-V352 WeakPolarHBondContact O-CG2 3.26Å; E348-V352 PolarHBondContact O-N 3.16Å
353	N	76.3	Confident	78.6	Confident	103 Å²	103	41.6 Å²	41.6	55%	0.551	21%	0.207	S	C	*	.	I	π-helix	trans	-87.9	-20.3	-174.4	-61.1	-31.3	0	0	0	112.9	E348 D355	E348-N353 PolarHBondContact O-N 3.03Å; N353-D355 HydrophobicContact CB-CB 4.49Å; N353-D355 PolarHBondContact O-N 2.88Å
354	F	77	Confident	78.7	Confident	99 Å²	99	48.3 Å²	48.3	43%	0.434	23%	0.233	S	C	.	.			trans	50.6	34.7	-172.3	-66.7	-85.3	0	0	0	113.1	C349 L350 Y351 T394 I398	C349-F354 WeakPolarHBondContact O-CA 3.28Å; C349-F354 PolarHBondContact O-N 3.49Å; L350-F354 WeakPolarHBondContact O-CD1 3.47Å; Y351-F354 WeakPolarHBondContact O-CE2 2.87Å; F354-T394 HydrophobicContact CD1-CG2 3.99Å; F354-T394 HydrophobicContact CE1-CG2 3.88Å; F354-I398 HydrophobicContact CD1-CD1 4.07Å
355	D	80.2	Confident	78.9	Confident	78 Å²	78	51.7 Å²	51.7	42%	0.417	25%	0.248	S	C	.	.			trans	-93.3	104.6	176.9	-176.5	-1.6	0	0	0	110.5	C349 N353 D357 G358 A359	C349-D355 PolarHBondContact O-N 3.42Å; C349-D355 VanDerWaalsContact O-N 3.13Å; N353-D355 HydrophobicContact CB-CB 4.49Å; N353-D355 PolarHBondContact O-N 2.88Å; D355-D357 PolarHBondContact OD1-N 3.45Å; D355-G358 PolarHBondContact OD1-N 3.28Å; D355-G358 VanDerWaalsContact OD1-N 3.1Å; D355-A359 VanDerWaalsContact O-CB 3.24Å; D355-A359 WeakPolarHBondContact O-CB 3.4Å; D355-A359 PolarHBondContact O-N 2.87Å
356	F	73.1	Confident	78.7	Confident	34 Å²	34	48.7 Å²	48.7	15%	0.149	23%	0.234	C	C	.	.	H	α-helix	trans	-77.7	-25.2	-178.5	-59.5	-72.7	0	0	0	113.7	L350 Q360 I391 T394 F395 I398	L350-F356 HydrophobicContact CD1-CD1 4.4Å; L350-F356 HydrophobicContact CD1-CE1 4.1Å; F356-Q360 WeakPolarHBondContact O-CB 3.34Å; F356-Q360 PolarHBondContact O-N 3.3Å; F356-I391 HydrophobicContact CD1-CG2 3.98Å; F356-T394 HydrophobicContact CE1-CG2 4.21Å; F356-T394 HydrophobicContact CZ-CG2 4.14Å; F356-F395 HydrophobicContact CD1-CD2 4.28Å; F356-F395 AromaticContact CD2-CD2 3.92Å; F356-F395 HydrophobicContact CD2-CD2 3.92Å; F356-F395 HydrophobicContact CD2-CE2 4.33Å; F356-F395 HydrophobicContact CE1-CB 4.26Å; F356-F395 HydrophobicContact CE1-CD2 4.32Å; F356-F395 AromaticContact CE2-CD2 3.97Å; F356-F395 HydrophobicContact CE2-CD2 3.97Å; F356-F395 HydrophobicContact CG-CD2 4.08Å; F356-F395 HydrophobicContact CZ-CB 4.44Å; F356-F395 HydrophobicContact CZ-CD2 4.17Å; F356-I398 HydrophobicContact CE2-CD1 4.25Å; F356-I398 HydrophobicContact CZ-CD1 3.9Å
357	D	78.5	Confident	78.5	Confident	76 Å²	76	52.7 Å²	52.7	41%	0.406	25%	0.253	S	S	.	.	H	α-helix	trans	-78.9	-41.2	177.9	-162.9	61.6	0	0	0	110.7	D355 Q360 K361 K410	D355-D357 PolarHBondContact OD1-N 3.45Å; D357-Q360 PolarHBondContact O-N 2.9Å; D357-K361 PolarHBondContact O-N 3.39Å; D357-K361 IonicContact OD2-NZ 2.76Å; D357-K361 PolarHBondContact OD2-NZ 3.01Å; D357-K410 IonicContact OD1-NZ 3.35Å; D357-K410 PolarHBondContact OD1-NZ 3.06Å
358	G	77.8	Confident	78.1	Confident	17 Å²	17	55.3 Å²	55.3	18%	0.175	27%	0.271	C	S	.	.	H	α-helix	trans	-59.9	-48.6	169.4	0	0	0	0	0	112.1	D355 Q360 K361 K362	D355-G358 PolarHBondContact OD1-N 3.28Å; D355-G358 VanDerWaalsContact OD1-N 3.1Å; G358-Q360 VanDerWaalsContact C-N 3.26Å; G358-Q360 PolarHBondContact O-N 3.42Å; G358-K361 PolarHBondContact O-N 3.36Å; G358-K362 WeakPolarHBondContact O-CB 3.26Å; G358-K362 VanDerWaalsContact O-CG 3.26Å; G358-K362 WeakPolarHBondContact O-CG 3.21Å; G358-K362 PolarHBondContact O-N 3.37Å
359	A	77.4	Confident	77.9	Confident	0 Å²	0	53.3 Å²	53.3	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-58.7	-36.1	178.3	0	0	0	0	0	112.8	F346 C349 D355 K362 L363	F346-A359 HydrophobicContact CD2-CB 4Å; F346-A359 VanDerWaalsContact CD2-O 3.3Å; F346-A359 WeakPolarHBondContact CD2-O 3.46Å; F346-A359 HydrophobicContact CE2-CB 3.88Å; C349-A359 HydrophobicContact CB-CB 4.42Å; D355-A359 VanDerWaalsContact O-CB 3.24Å; D355-A359 WeakPolarHBondContact O-CB 3.4Å; D355-A359 PolarHBondContact O-N 2.87Å; A359-K362 PolarHBondContact O-N 3.1Å; A359-L363 PolarHBondContact O-N 2.99Å
360	Q	74.8	Confident	77.7	Confident	37 Å²	37	52.7 Å²	52.7	17%	0.173	26%	0.258	C	S	.	.	H	α-helix	trans	-72.3	-41	179.2	-171.1	-178.2	-12.7	0	0	112.9	F356 D357 G358 K362 L363 R364 K410	F356-Q360 WeakPolarHBondContact O-CB 3.34Å; F356-Q360 PolarHBondContact O-N 3.3Å; D357-Q360 PolarHBondContact O-N 2.9Å; G358-Q360 VanDerWaalsContact C-N 3.26Å; G358-Q360 PolarHBondContact O-N 3.42Å; Q360-K362 VanDerWaalsContact C-N 3.3Å; Q360-L363 PolarHBondContact O-N 3.38Å; Q360-R364 PolarHBondContact O-N 3.11Å; Q360-K410 PolarHBondContact NE2-O 2.72Å; Q360-K410 VanDerWaalsContact OE1-CD 3.32Å
361	K	81.7	Confident	77.3	Confident	122 Å²	122	55.3 Å²	55.3	53%	0.53	27%	0.274	S	S	.	.	H	α-helix	trans	-60.1	-44.3	172.1	-74	167.1	177.6	146.9	0	110.4	D357 G358 L363 R364 E365	D357-K361 PolarHBondContact O-N 3.39Å; D357-K361 IonicContact OD2-NZ 2.76Å; D357-K361 PolarHBondContact OD2-NZ 3.01Å; G358-K361 PolarHBondContact O-N 3.36Å; K361-L363 VanDerWaalsContact C-N 3.32Å; K361-L363 PolarHBondContact O-N 2.7Å; K361-R364 PolarHBondContact O-N 3.5Å; K361-E365 PolarHBondContact O-N 2.89Å; K361-E365 VanDerWaalsContact O-N 3.12Å
362	K	80.9	Confident	76.8	Confident	37 Å²	37	53.9 Å²	53.9	16%	0.161	27%	0.27	C	S	.	.	H	α-helix	trans	-63.1	-34.3	176.3	-67.2	-74.2	161.4	-173.4	0	112.8	P342 E345 F346 G358 A359 Q360 R364 E365 C366	P342-K362 HydrophobicContact CB-CD 4.47Å; E345-K362 HydrophobicContact CB-CD 4.45Å; E345-K362 VanDerWaalsContact CD-CE 3.42Å; E345-K362 HydrophobicContact CG-CD 4.22Å; E345-K362 IonicContact OE1-NZ 2.71Å; E345-K362 WeakPolarHBondContact OE2-CE 3.3Å; E345-K362 IonicContact OE2-NZ 2.95Å; E345-K362 PolarHBondContact OE2-NZ 3.49Å; F346-K362 HydrophobicContact CB-CB 4.24Å; F346-K362 HydrophobicContact CD2-CB 4.49Å; G358-K362 WeakPolarHBondContact O-CB 3.26Å; G358-K362 VanDerWaalsContact O-CG 3.26Å; G358-K362 WeakPolarHBondContact O-CG 3.21Å; G358-K362 PolarHBondContact O-N 3.37Å; A359-K362 PolarHBondContact O-N 3.1Å; Q360-K362 VanDerWaalsContact C-N 3.3Å; K362-R364 PolarHBondContact O-N 3.49Å; K362-E365 WeakPolarHBondContact CD-OE2 3.3Å; K362-E365 WeakPolarHBondContact CE-OE2 3.32Å; K362-E365 IonicContact NZ-OE2 3Å; K362-E365 PolarHBondContact NZ-OE2 2.93Å; K362-E365 PolarHBondContact O-N 2.83Å; K362-C366 WeakPolarHBondContact O-CB 3.31Å; K362-C366 PolarHBondContact O-N 2.88Å; K362-C366 PolarHBondContact O-SG 3.33Å
363	L	79.8	Confident	76.3	Confident	17 Å²	17	51.9 Å²	51.9	9%	0.089	26%	0.258	C	S	.	.	H	α-helix	trans	-63.8	-39.6	174.9	-162.6	158.7	0	0	0	111.8	F346 A359 Q360 K361 C366 E367 I384 A387 R388 I391	F346-L363 HydrophobicContact CE2-CB 4.44Å; F346-L363 HydrophobicContact CE2-CD1 4.37Å; A359-L363 PolarHBondContact O-N 2.99Å; Q360-L363 PolarHBondContact O-N 3.38Å; K361-L363 VanDerWaalsContact C-N 3.32Å; K361-L363 PolarHBondContact O-N 2.7Å; L363-C366 WeakPolarHBondContact O-CB 3.39Å; L363-C366 PolarHBondContact O-N 3.45Å; L363-E367 PolarHBondContact O-N 3.43Å; L363-I384 HydrophobicContact CD2-CG2 4.43Å; L363-A387 HydrophobicContact CD1-CB 4.1Å; L363-R388 HydrophobicContact CD1-CG 4.37Å; L363-I391 HydrophobicContact CD1-CD1 3.82Å
364	R	80.4	Confident	75.8	Confident	141 Å²	141	50.8 Å²	50.8	53%	0.532	25%	0.248	S	C	.	.	H	α-helix	trans	-65.6	-40.5	174.3	-66.4	-175.8	178.9	-177.1	-0.4	112	Q360 K361 K362 C366 E367 S368 N412	Q360-R364 PolarHBondContact O-N 3.11Å; K361-R364 PolarHBondContact O-N 3.5Å; K362-R364 PolarHBondContact O-N 3.49Å; R364-C366 VanDerWaalsContact C-N 3.34Å; R364-E367 PolarHBondContact O-N 3.39Å; R364-S368 PolarHBondContact O-N 2.95Å; R364-N412 PolarHBondContact NH2-OD1 3.34Å
365	E	80.2	Confident	75.2	Confident	78 Å²	78	46.7 Å²	46.7	36%	0.364	23%	0.23	S	C	.	.	H	α-helix	trans	-63	-41.9	172.7	-68.1	172.8	-170.9	0	0	110.9	P342 K361 K362 E367 S368 V369	P342-E365 HydrophobicContact CB-CB 4.19Å; K361-E365 PolarHBondContact O-N 2.89Å; K361-E365 VanDerWaalsContact O-N 3.12Å; K362-E365 WeakPolarHBondContact CD-OE2 3.3Å; K362-E365 WeakPolarHBondContact CE-OE2 3.32Å; K362-E365 IonicContact NZ-OE2 3Å; K362-E365 PolarHBondContact NZ-OE2 2.93Å; K362-E365 PolarHBondContact O-N 2.83Å; E365-E367 VanDerWaalsContact C-N 3.32Å; E365-E367 PolarHBondContact O-N 2.92Å; E365-S368 PolarHBondContact O-N 2.92Å; E365-S368 PolarHBondContact O-OG 3Å; E365-V369 WeakPolarHBondContact O-CG2 3.43Å; E365-V369 PolarHBondContact O-N 2.86Å; E365-V369 VanDerWaalsContact O-N 3.13Å
366	C	77.6	Confident	74.5	Confident	2 Å²	2	43 Å²	43	1%	0.014	21%	0.21	C	C	.	.	H	α-helix	trans	-58.7	-42	175.3	-68.5	0	0	0	0	111.7	P342 I343 K362 L363 R364 S368 V369 L370	P342-C366 VanDerWaalsContact C-SG 3.53Å; P342-C366 PolarHBondContact O-SG 3.36Å; I343-C366 HydrophobicContact CG1-CB 4.14Å; I343-C366 VanDerWaalsContact CG1-SG 3.53Å; K362-C366 WeakPolarHBondContact O-CB 3.31Å; K362-C366 PolarHBondContact O-N 2.88Å; K362-C366 PolarHBondContact O-SG 3.33Å; L363-C366 WeakPolarHBondContact O-CB 3.39Å; L363-C366 PolarHBondContact O-N 3.45Å; R364-C366 VanDerWaalsContact C-N 3.34Å; C366-S368 VanDerWaalsContact C-N 3.34Å; C366-S368 PolarHBondContact O-N 2.87Å; C366-V369 CarbonylContact O-C 3.56Å; C366-V369 PolarHBondContact O-N 2.92Å; C366-V369 VanDerWaalsContact O-N 3.13Å; C366-L370 HydrophobicContact CB-CD1 3.9Å; C366-L370 WeakPolarHBondContact O-CB 3.37Å; C366-L370 WeakPolarHBondContact O-CD1 3.43Å; C366-L370 PolarHBondContact O-N 2.99Å
367	E	76.2	Confident	74	Confident	87 Å²	87	45.3 Å²	45.3	41%	0.407	23%	0.227	S	C	.	.	H	α-helix	trans	-57.1	-47.9	178.9	-173.3	171.6	-165.5	0	0	111.4	L363 R364 E365 V369 L370 V371 I384	L363-E367 PolarHBondContact O-N 3.43Å; R364-E367 PolarHBondContact O-N 3.39Å; E365-E367 VanDerWaalsContact C-N 3.32Å; E365-E367 PolarHBondContact O-N 2.92Å; E367-V369 VanDerWaalsContact C-N 3.3Å; E367-V369 PolarHBondContact O-N 3.43Å; E367-L370 PolarHBondContact O-N 3.5Å; E367-V371 VanDerWaalsContact O-CG2 3.27Å; E367-V371 WeakPolarHBondContact O-CG2 3.29Å; E367-V371 PolarHBondContact O-N 3.41Å; E367-V371 VanDerWaalsContact O-N 3.11Å; E367-I384 HydrophobicContact CG-CD1 4.1Å
368	S	74.3	Confident	73.5	Confident	57 Å²	57	45.5 Å²	45.5	40%	0.399	24%	0.239	S	C	.	.	H	α-helix	trans	-61.5	-38	176	67.4	0	0	0	0	113.1	R364 E365 C366 N372	R364-S368 PolarHBondContact O-N 2.95Å; E365-S368 PolarHBondContact O-N 2.92Å; E365-S368 PolarHBondContact O-OG 3Å; C366-S368 VanDerWaalsContact C-N 3.34Å; C366-S368 PolarHBondContact O-N 2.87Å; S368-N372 PolarHBondContact O-ND2 2.96Å
369	V	75.9	Confident	72.9	Confident	9 Å²	9	44.7 Å²	44.7	6%	0.055	23%	0.231	C	C	.	.	H	α-helix	trans	-74.5	-34.7	-179.1	168.8	0	0	0	0	111.7	Y55 R306 P342 E365 C366 E367	Y55-V369 HydrophobicContact CD2-CG2 3.82Å; Y55-V369 HydrophobicContact CE2-CG2 4.26Å; Y55-V369 HydrophobicContact CG-CG2 4.19Å; R306-V369 PolarHBondContact NH2-O 3.39Å; P342-V369 HydrophobicContact CG-CG2 4.47Å; E365-V369 WeakPolarHBondContact O-CG2 3.43Å; E365-V369 PolarHBondContact O-N 2.86Å; E365-V369 VanDerWaalsContact O-N 3.13Å; C366-V369 CarbonylContact O-C 3.56Å; C366-V369 PolarHBondContact O-N 2.92Å; C366-V369 VanDerWaalsContact O-N 3.13Å; E367-V369 VanDerWaalsContact C-N 3.3Å; E367-V369 PolarHBondContact O-N 3.43Å
370	L	73.4	Confident	72.7	Confident	1 Å²	1	46 Å²	46	1%	0.005	24%	0.238	C	C	.	.	H	α-helix	trans	-71.8	-34.4	176	-89.9	108.8	0	0	0	112.7	I343 C366 E367 N372 D373 L376 L380 F383	I343-L370 HydrophobicContact CD1-CD1 3.83Å; I343-L370 HydrophobicContact CD1-CG 4.4Å; I343-L370 HydrophobicContact CG1-CD1 4.25Å; C366-L370 HydrophobicContact CB-CD1 3.9Å; C366-L370 WeakPolarHBondContact O-CB 3.37Å; C366-L370 WeakPolarHBondContact O-CD1 3.43Å; C366-L370 PolarHBondContact O-N 2.99Å; E367-L370 PolarHBondContact O-N 3.5Å; L370-N372 PolarHBondContact O-N 2.93Å; L370-D373 PolarHBondContact O-N 3.33Å; L370-L376 HydrophobicContact CD2-CB 4.07Å; L370-L376 HydrophobicContact CD2-CD1 4.5Å; L370-L376 HydrophobicContact CG-CB 4.38Å; L370-L376 HydrophobicContact CG-CD1 4.34Å; L370-L380 HydrophobicContact CB-CD1 4.11Å; L370-L380 HydrophobicContact CB-CG 4.31Å; L370-L380 HydrophobicContact CD2-CB 4.5Å; L370-F383 HydrophobicContact CD1-CD1 4.02Å; L370-F383 HydrophobicContact CD1-CE1 4.01Å; L370-F383 HydrophobicContact CD2-CB 4.38Å; L370-F383 HydrophobicContact CD2-CD1 4.21Å; L370-F383 HydrophobicContact CD2-CG 4.35Å
371	V	71.2	Confident	72.7	Confident	59 Å²	59	51.8 Å²	51.8	36%	0.358	27%	0.265	S	S	.	.	H	α-helix	trans	-64.4	-26.6	177.6	173.4	0	0	0	0	112	K80 E367 L380	K80-V371 WeakPolarHBondContact CE-O 3.34Å; K80-V371 PolarHBondContact NZ-O 3.39Å; E367-V371 VanDerWaalsContact O-CG2 3.27Å; E367-V371 WeakPolarHBondContact O-CG2 3.29Å; E367-V371 PolarHBondContact O-N 3.41Å; E367-V371 VanDerWaalsContact O-N 3.11Å; V371-L380 HydrophobicContact CB-CD1 4.44Å; V371-L380 HydrophobicContact CG2-CD1 3.44Å; V371-L380 VanDerWaalsContact CG2-CD1 3.44Å
372	N	66.9	Low	72.6	Confident	25 Å²	25	48.8 Å²	48.8	13%	0.134	25%	0.254	C	S	.	.	T	Hydrogen-bonded Turn	trans	-91.4	-8.4	-175.8	-64.7	-16.5	0	0	0	113.5	F76 I82 S368 L370	F76-N372 WeakPolarHBondContact CE1-O 3.42Å; I82-N372 HydrophobicContact CD1-CB 4.1Å; S368-N372 PolarHBondContact O-ND2 2.96Å; L370-N372 PolarHBondContact O-N 2.93Å
373	D	69.5	Low	72.6	Confident	11 Å²	11	47.1 Å²	47.1	6%	0.059	25%	0.247	C	C	.	.			trans	-94.2	129.2	-178	-99.5	44.2	0	0	0	112.4	R306 Y307 L370 F375 L376 V377	R306-D373 IonicContact CZ-OD1 3.07Å; R306-D373 IonicContact CZ-OD2 3.82Å; R306-D373 IonicContact NE-OD2 2.95Å; R306-D373 VanDerWaalsContact NH1-CG 3.29Å; R306-D373 IonicContact NH1-OD1 2.82Å; R306-D373 PolarHBondContact NH1-OD1 3.33Å; R306-D373 IonicContact NH1-OD2 2.63Å; R306-D373 PolarHBondContact NH1-OD2 3Å; R306-D373 VanDerWaalsContact NH1-OD2 3.14Å; R306-D373 IonicContact NH2-OD1 3.72Å; R306-D373 PolarHBondContact NH2-OD1 2.95Å; R306-D373 IonicContact NH2-OD2 3.71Å; R306-D373 PolarHBondContact NH2-OD2 3.02Å; Y307-D373 WeakPolarHBondContact CE1-OD2 3.36Å; Y307-D373 PolarHBondContact OH-OD2 2.95Å; Y307-D373 VanDerWaalsContact OH-OD2 3.09Å; L370-D373 PolarHBondContact O-N 3.33Å; D373-F375 VanDerWaalsContact C-N 3.33Å; D373-F375 PolarHBondContact O-N 3.41Å; D373-L376 HydrophobicContact CB-CB 3.88Å; D373-L376 HydrophobicContact CB-CD1 3.89Å; D373-L376 HydrophobicContact CB-CG 4.09Å; D373-L376 PolarHBondContact O-N 3.48Å; D373-L376 WeakPolarHBondContact OD2-CD1 3.41Å; D373-V377 VanDerWaalsContact O-CG2 3.29Å; D373-V377 WeakPolarHBondContact O-CG2 3.47Å
374	F	65.4	Low	72.6	Confident	79 Å²	79	47 Å²	47	35%	0.346	25%	0.246	S	C	.	.	T	Hydrogen-bonded Turn	trans	-56.2	-41.1	179.8	-177.7	-105.9	0	0	0	113.7	P72 L73 F76	P72-F374 HydrophobicContact CB-CZ 4.18Å; L73-F374 HydrophobicContact CD2-CB 3.8Å; L73-F374 HydrophobicContact CD2-CD1 3.48Å; L73-F374 VanDerWaalsContact CD2-CD1 3.48Å; L73-F374 HydrophobicContact CD2-CD2 4.47Å; L73-F374 HydrophobicContact CD2-CE1 4.13Å; L73-F374 HydrophobicContact CD2-CG 3.67Å; F76-F374 HydrophobicContact CB-CD2 3.46Å; F76-F374 VanDerWaalsContact CB-CD2 3.46Å; F76-F374 HydrophobicContact CB-CE2 3.9Å; F76-F374 HydrophobicContact CB-CG 4.48Å; F76-F374 HydrophobicContact CD1-CB 3.92Å; F76-F374 AromaticContact CD1-CD2 3.96Å; F76-F374 HydrophobicContact CD1-CD2 3.96Å; F76-F374 HydrophobicContact CD1-CG 4.45Å; F76-F374 AromaticContact CD2-CD2 3.67Å; F76-F374 HydrophobicContact CD2-CD2 3.67Å; F76-F374 HydrophobicContact CD2-CE2 4.29Å; F76-F374 HydrophobicContact CE1-CB 4.11Å; F76-F374 HydrophobicContact CE2-CD2 4.33Å; F76-F374 HydrophobicContact CG-CB 4.3Å; F76-F374 AromaticContact CG-CD2 3.44Å; F76-F374 HydrophobicContact CG-CD2 3.44Å; F76-F374 VanDerWaalsContact CG-CD2 3.44Å; F76-F374 HydrophobicContact CG-CE2 4.24Å; F76-F374 HydrophobicContact CG-CG 4.35Å
375	F	63.3	Low	72.5	Confident	14 Å²	14	45.8 Å²	45.8	6%	0.061	25%	0.247	C	C	.	.	T	Hydrogen-bonded Turn	trans	-85.3	-22.4	-175.8	-61.4	-70.7	0	0	0	114.3	L73 F271 F274 Y307 D373	L73-F375 HydrophobicContact CD2-CE2 4.1Å; L73-F375 HydrophobicContact CD2-CZ 4.11Å; F271-F375 HydrophobicContact CB-CE1 4.27Å; F271-F375 AromaticContact CD1-CE1 3.47Å; F271-F375 HydrophobicContact CD1-CE1 3.47Å; F271-F375 VanDerWaalsContact CD1-CE1 3.47Å; F271-F375 AromaticContact CD1-CZ 3.51Å; F271-F375 HydrophobicContact CD1-CZ 3.51Å; F271-F375 HydrophobicContact CD2-CE1 4.2Å; F271-F375 AromaticContact CD2-CZ 3.85Å; F271-F375 HydrophobicContact CD2-CZ 3.85Å; F271-F375 AromaticContact CE1-CE1 3.82Å; F271-F375 HydrophobicContact CE1-CE1 3.82Å; F271-F375 AromaticContact CE1-CZ 3.37Å; F271-F375 HydrophobicContact CE1-CZ 3.37Å; F271-F375 HydrophobicContact CE2-CE1 4.43Å; F271-F375 HydrophobicContact CE2-CE2 4.41Å; F271-F375 AromaticContact CE2-CZ 3.65Å; F271-F375 HydrophobicContact CE2-CZ 3.65Å; F271-F375 AromaticContact CG-CE1 3.71Å; F271-F375 HydrophobicContact CG-CE1 3.71Å; F271-F375 AromaticContact CG-CZ 3.78Å; F271-F375 HydrophobicContact CG-CZ 3.78Å; F271-F375 HydrophobicContact CZ-CE1 4.29Å; F271-F375 HydrophobicContact CZ-CE2 4.32Å; F271-F375 AromaticContact CZ-CZ 3.45Å; F271-F375 HydrophobicContact CZ-CZ 3.45Å; F271-F375 VanDerWaalsContact CZ-CZ 3.45Å; F274-F375 HydrophobicContact CB-CB 4.38Å; F274-F375 HydrophobicContact CB-CD1 4.4Å; F274-F375 HydrophobicContact CD2-CB 3.86Å; F274-F375 HydrophobicContact CD2-CD1 4.41Å; F274-F375 HydrophobicContact CD2-CG 4.24Å; F274-F375 HydrophobicContact CE2-CB 4.28Å; F274-F375 HydrophobicContact CG-CB 4.07Å; Y307-F375 HydrophobicContact CE1-CD2 4.48Å; D373-F375 VanDerWaalsContact C-N 3.33Å; D373-F375 PolarHBondContact O-N 3.41Å
376	L	65.8	Low	72.3	Confident	0 Å²	0	43.2 Å²	43.2	0%	0	24%	0.236	C	C	.	.	T	Hydrogen-bonded Turn	trans	-96.8	-4.7	-167	-66.6	173.8	0	0	0	113.3	F274 Y307 T310 L370 D373 A378 C379 L380	F274-L376 HydrophobicContact CE1-CD2 3.84Å; F274-L376 HydrophobicContact CZ-CD2 3.97Å; Y307-L376 HydrophobicContact CD1-CD1 4.22Å; Y307-L376 HydrophobicContact CD1-CD2 4.27Å; Y307-L376 HydrophobicContact CD1-CG 4.27Å; Y307-L376 HydrophobicContact CE1-CD1 4Å; Y307-L376 HydrophobicContact CE1-CG 4.18Å; T310-L376 HydrophobicContact CG2-CD1 4.36Å; T310-L376 HydrophobicContact CG2-CD2 4.03Å; T310-L376 WeakPolarHBondContact OG1-CD2 3.33Å; L370-L376 HydrophobicContact CD2-CB 4.07Å; L370-L376 HydrophobicContact CD2-CD1 4.5Å; L370-L376 HydrophobicContact CG-CB 4.38Å; L370-L376 HydrophobicContact CG-CD1 4.34Å; D373-L376 HydrophobicContact CB-CB 3.88Å; D373-L376 HydrophobicContact CB-CD1 3.89Å; D373-L376 HydrophobicContact CB-CG 4.09Å; D373-L376 PolarHBondContact O-N 3.48Å; D373-L376 WeakPolarHBondContact OD2-CD1 3.41Å; L376-A378 VanDerWaalsContact C-N 3.3Å; L376-A378 PolarHBondContact O-N 3.42Å; L376-C379 HydrophobicContact CD2-CB 4.47Å; L376-C379 PolarHBondContact O-N 3.3Å; L376-L380 PolarHBondContact O-N 3.46Å; L376-L380 VanDerWaalsContact O-N 3.17Å
377	V	64.3	Low	72.4	Confident	82 Å²	82	43.1 Å²	43.1	50%	0.497	24%	0.235	S	C	.	.	G	3₁₀ helix	trans	-55.3	-44.4	178.1	-174.4	0	0	0	0	111.7	F76 D373 C379	F76-V377 HydrophobicContact CE2-CG2 4.37Å; F76-V377 HydrophobicContact CZ-CG2 4.12Å; D373-V377 VanDerWaalsContact O-CG2 3.29Å; D373-V377 WeakPolarHBondContact O-CG2 3.47Å; V377-C379 PolarHBondContact O-N 2.95Å
378	A	67.1	Low	72.5	Confident	80 Å²	80	42.2 Å²	42.2	66%	0.661	23%	0.228	S	C	*	.	G	3₁₀ helix	trans	-73.1	-14.2	179.5	0	0	0	0	0	113.9	L376	L376-A378 VanDerWaalsContact C-N 3.3Å; L376-A378 PolarHBondContact O-N 3.42Å
379	C	65.8	Low	72.6	Confident	1 Å²	1	41.8 Å²	41.8	1%	0.007	22%	0.221	C	C	.	.	G	3₁₀ helix	trans	-104.2	-3.3	-175.9	-70.3	0	0	0	0	112.9	T314 L376 V377 F383	T314-C379 HydrophobicContact CG2-CB 4.23Å; L376-C379 HydrophobicContact CD2-CB 4.47Å; L376-C379 PolarHBondContact O-N 3.3Å; V377-C379 PolarHBondContact O-N 2.95Å; C379-F383 WeakPolarHBondContact O-CB 3.45Å; C379-F383 PolarHBondContact O-N 2.95Å
380	L	72.3	Confident	72.6	Confident	28 Å²	28	42 Å²	42	15%	0.147	22%	0.221	C	C	.	.	H	α-helix	trans	-63.1	-54.6	-171.1	-172	155.9	0	0	0	112.2	L370 V371 L376 F383 I384	L370-L380 HydrophobicContact CB-CD1 4.11Å; L370-L380 HydrophobicContact CB-CG 4.31Å; L370-L380 HydrophobicContact CD2-CB 4.5Å; V371-L380 HydrophobicContact CB-CD1 4.44Å; V371-L380 HydrophobicContact CG2-CD1 3.44Å; V371-L380 VanDerWaalsContact CG2-CD1 3.44Å; L376-L380 PolarHBondContact O-N 3.46Å; L376-L380 VanDerWaalsContact O-N 3.17Å; L380-F383 PolarHBondContact O-N 2.88Å; L380-I384 HydrophobicContact CD2-CD1 3.51Å; L380-I384 HydrophobicContact CD2-CG1 4.41Å; L380-I384 HydrophobicContact CG-CD1 4.28Å; L380-I384 WeakPolarHBondContact O-CG1 3.32Å; L380-I384 PolarHBondContact O-N 2.91Å
381	E	75.5	Confident	72.8	Confident	157 Å²	157	42.8 Å²	42.8	73%	0.734	23%	0.225	S	C	*	.	H	α-helix	trans	-65.1	-49.1	-177.3	-65.5	-177.8	174.8	0	0	111.3	F383 I384 E385	E381-F383 VanDerWaalsContact C-N 3.26Å; E381-F383 PolarHBondContact O-N 3.31Å; E381-I384 PolarHBondContact O-N 3.12Å; E381-E385 PolarHBondContact O-N 3.31Å
382	D	78.4	Confident	72.9	Confident	59 Å²	59	40.9 Å²	40.9	32%	0.316	21%	0.212	S	C	.	.	H	α-helix	trans	-54.4	-43.3	174.7	-82.6	-8.2	0	0	0	111.2	R280 T314 N386	R280-D382 IonicContact NH1-OD2 3.82Å; R280-D382 PolarHBondContact NH1-OD2 2.63Å; T314-D382 HydrophobicContact CG2-CB 4.11Å; D382-N386 VanDerWaalsContact O-CB 3.25Å; D382-N386 WeakPolarHBondContact O-CB 3.45Å; D382-N386 VanDerWaalsContact O-CG 3.3Å; D382-N386 PolarHBondContact O-N 2.95Å; D382-N386 PolarHBondContact O-ND2 2.85Å
383	F	80.9	Confident	73.4	Confident	2 Å²	2	40.3 Å²	40.3	1%	0.009	21%	0.209	C	C	.	.	H	α-helix	trans	-67.1	-46.1	-179.1	177.7	-95.9	0	0	0	111.4	T310 I313 T314 I343 L370 C379 L380 E381 E385 N386 A387	T310-F383 HydrophobicContact CG2-CD2 4.03Å; T310-F383 HydrophobicContact CG2-CE2 3.88Å; T310-F383 HydrophobicContact CG2-CZ 4.48Å; I313-F383 HydrophobicContact CB-CD2 3.98Å; I313-F383 HydrophobicContact CB-CE2 3.95Å; I313-F383 HydrophobicContact CD1-CD2 4.46Å; I313-F383 HydrophobicContact CD1-CE2 3.57Å; I313-F383 HydrophobicContact CD1-CZ 4.21Å; I313-F383 HydrophobicContact CG1-CE2 4.34Å; I313-F383 HydrophobicContact CG2-CD2 3.67Å; I313-F383 HydrophobicContact CG2-CE2 3.83Å; T314-F383 HydrophobicContact CG2-CB 3.94Å; T314-F383 HydrophobicContact CG2-CD2 4.47Å; I343-F383 HydrophobicContact CG2-CZ 4.14Å; L370-F383 HydrophobicContact CD1-CD1 4.02Å; L370-F383 HydrophobicContact CD1-CE1 4.01Å; L370-F383 HydrophobicContact CD2-CB 4.38Å; L370-F383 HydrophobicContact CD2-CD1 4.21Å; L370-F383 HydrophobicContact CD2-CG 4.35Å; C379-F383 WeakPolarHBondContact O-CB 3.45Å; C379-F383 PolarHBondContact O-N 2.95Å; L380-F383 PolarHBondContact O-N 2.88Å; E381-F383 VanDerWaalsContact C-N 3.26Å; E381-F383 PolarHBondContact O-N 3.31Å; F383-E385 PolarHBondContact O-N 3.47Å; F383-N386 PolarHBondContact O-N 2.83Å; F383-A387 HydrophobicContact CE1-CB 4.46Å; F383-A387 WeakPolarHBondContact O-CB 3.42Å; F383-A387 PolarHBondContact O-N 3.45Å
384	I	80.5	Confident	73.8	Confident	14 Å²	14	40.1 Å²	40.1	7%	0.072	21%	0.208	C	C	.	.	H	α-helix	trans	-62.4	-45.8	-179.9	-70.3	176.5	0	0	0	110.6	L363 E367 L380 E381 A387 R388	L363-I384 HydrophobicContact CD2-CG2 4.43Å; E367-I384 HydrophobicContact CG-CD1 4.1Å; L380-I384 HydrophobicContact CD2-CD1 3.51Å; L380-I384 HydrophobicContact CD2-CG1 4.41Å; L380-I384 HydrophobicContact CG-CD1 4.28Å; L380-I384 WeakPolarHBondContact O-CG1 3.32Å; L380-I384 PolarHBondContact O-N 2.91Å; E381-I384 PolarHBondContact O-N 3.12Å; I384-A387 PolarHBondContact O-N 3.07Å; I384-R388 HydrophobicContact CG2-CG 4.46Å; I384-R388 VanDerWaalsContact CG2-CZ 3.47Å; I384-R388 VanDerWaalsContact CG2-NE 3.35Å; I384-R388 WeakPolarHBondContact O-CB 3.4Å; I384-R388 WeakPolarHBondContact O-CG 3.19Å; I384-R388 PolarHBondContact O-N 3.42Å
385	E	77.1	Confident	74.3	Confident	116 Å²	116	37.7 Å²	37.7	54%	0.542	20%	0.197	S	C	.	.	H	α-helix	trans	-62.2	-47.1	177.5	-71	-167.6	166.7	0	0	111.5	E381 F383 A387 R388 L389	E381-E385 PolarHBondContact O-N 3.31Å; F383-E385 PolarHBondContact O-N 3.47Å; E385-A387 PolarHBondContact O-N 2.86Å; E385-R388 PolarHBondContact O-N 3.41Å; E385-L389 VanDerWaalsContact O-CG 3.26Å; E385-L389 WeakPolarHBondContact O-CG 3.18Å; E385-L389 PolarHBondContact O-N 3.26Å
386	N	77.8	Confident	74.7	Confident	25 Å²	25	38 Å²	38	13%	0.134	20%	0.201	C	C	.	.	H	α-helix	trans	-65.5	-39	178.9	-78.3	-62.3	0	0	0	112.9	I313 R321 D382 F383 L389 F390	I313-N386 HydrophobicContact CG2-CB 3.79Å; I313-N386 WeakPolarHBondContact O-CB 3.28Å; R321-N386 PolarHBondContact NH1-OD1 3.37Å; R321-N386 PolarHBondContact NH2-OD1 3.18Å; D382-N386 VanDerWaalsContact O-CB 3.25Å; D382-N386 WeakPolarHBondContact O-CB 3.45Å; D382-N386 VanDerWaalsContact O-CG 3.3Å; D382-N386 PolarHBondContact O-N 2.95Å; D382-N386 PolarHBondContact O-ND2 2.85Å; F383-N386 PolarHBondContact O-N 2.83Å; N386-L389 PolarHBondContact O-N 3.21Å; N386-F390 VanDerWaalsContact O-CD2 3.26Å; N386-F390 WeakPolarHBondContact O-CD2 3.35Å; N386-F390 PolarHBondContact O-N 3.5Å
387	A	79.2	Confident	75.1	Confident	0 Å²	0	44.5 Å²	44.5	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-64.3	-44.8	175.9	0	0	0	0	0	110.9	F346 L363 F383 I384 E385 F390 I391	F346-A387 HydrophobicContact CE1-CB 4Å; F346-A387 HydrophobicContact CZ-CB 3.95Å; L363-A387 HydrophobicContact CD1-CB 4.1Å; F383-A387 HydrophobicContact CE1-CB 4.46Å; F383-A387 WeakPolarHBondContact O-CB 3.42Å; F383-A387 PolarHBondContact O-N 3.45Å; I384-A387 PolarHBondContact O-N 3.07Å; E385-A387 PolarHBondContact O-N 2.86Å; A387-F390 PolarHBondContact O-N 2.93Å; A387-I391 VanDerWaalsContact O-CG1 3.31Å; A387-I391 WeakPolarHBondContact O-CG1 3.36Å; A387-I391 PolarHBondContact O-N 2.87Å
388	R	77.1	Confident	75.9	Confident	68 Å²	68	45 Å²	45	26%	0.257	22%	0.224	S	C	.	.	H	α-helix	trans	-57.9	-51.4	173	-72.7	168.5	178.7	-178.4	4.1	110.4	L363 I384 E385 F390 I391 F392 L411 W421	L363-R388 HydrophobicContact CD1-CG 4.37Å; I384-R388 HydrophobicContact CG2-CG 4.46Å; I384-R388 VanDerWaalsContact CG2-CZ 3.47Å; I384-R388 VanDerWaalsContact CG2-NE 3.35Å; I384-R388 WeakPolarHBondContact O-CB 3.4Å; I384-R388 WeakPolarHBondContact O-CG 3.19Å; I384-R388 PolarHBondContact O-N 3.42Å; E385-R388 PolarHBondContact O-N 3.41Å; R388-F390 PolarHBondContact O-N 3.41Å; R388-F390 VanDerWaalsContact O-N 3.13Å; R388-I391 PolarHBondContact O-N 3.48Å; R388-F392 HydrophobicContact CB-CD2 4.48Å; R388-F392 WeakPolarHBondContact O-CD2 3.12Å; R388-F392 PolarHBondContact O-N 3.46Å; R388-L411 HydrophobicContact CB-CD2 4.29Å; R388-L411 VanDerWaalsContact CD-CD2 3.5Å; R388-L411 HydrophobicContact CG-CD2 3.72Å; R388-W421 HydrophobicContact CB-CH2 4.34Å; R388-W421 HydrophobicContact CB-CZ2 3.86Å
389	L	77.1	Confident	76.4	Confident	48 Å²	48	44.7 Å²	44.7	25%	0.251	21%	0.209	S	C	.	.	H	α-helix	trans	-51.6	-40.1	177.1	-71.9	172.1	0	0	0	111.6	E385 N386 E393 W421 L425	E385-L389 VanDerWaalsContact O-CG 3.26Å; E385-L389 WeakPolarHBondContact O-CG 3.18Å; E385-L389 PolarHBondContact O-N 3.26Å; N386-L389 PolarHBondContact O-N 3.21Å; L389-E393 VanDerWaalsContact O-CB 3.23Å; L389-E393 WeakPolarHBondContact O-CB 3.04Å; L389-E393 PolarHBondContact O-N 3.31Å; L389-W421 HydrophobicContact CB-CZ2 4.48Å; L389-W421 HydrophobicContact CD2-CH2 3.96Å; L389-W421 HydrophobicContact CD2-CZ2 3.51Å; L389-W421 HydrophobicContact CG-CZ2 3.89Å; L389-L425 HydrophobicContact CD2-CB 4.16Å; L389-L425 HydrophobicContact CD2-CD1 3.73Å; L389-L425 HydrophobicContact CD2-CG 4.26Å
390	F	76	Confident	76.7	Confident	12 Å²	12	50.4 Å²	50.4	5%	0.053	24%	0.236	C	C	.	.	H	α-helix	trans	-73.9	-42.9	179.7	-83	-48.9	0	0	0	115.9	R321 L325 L350 N386 A387 R388 F392 E393 T394	R321-F390 VanDerWaalsContact CD-CE2 3.48Å; R321-F390 HydrophobicContact CG-CE2 4.46Å; R321-F390 HydrophobicContact CG-CZ 3.94Å; L325-F390 HydrophobicContact CD1-CE1 3.88Å; L325-F390 HydrophobicContact CD1-CE2 4.24Å; L325-F390 HydrophobicContact CD1-CZ 3.47Å; L325-F390 VanDerWaalsContact CD1-CZ 3.47Å; L350-F390 HydrophobicContact CD2-CB 4.18Å; N386-F390 VanDerWaalsContact O-CD2 3.26Å; N386-F390 WeakPolarHBondContact O-CD2 3.35Å; N386-F390 PolarHBondContact O-N 3.5Å; A387-F390 PolarHBondContact O-N 2.93Å; R388-F390 PolarHBondContact O-N 3.41Å; R388-F390 VanDerWaalsContact O-N 3.13Å; F390-F392 PolarHBondContact O-N 3.26Å; F390-E393 PolarHBondContact O-N 2.91Å; F390-T394 WeakPolarHBondContact O-CB 3.39Å; F390-T394 PolarHBondContact O-N 3.36Å; F390-T394 PolarHBondContact O-OG1 3.47Å
391	I	77.8	Confident	76.8	Confident	18 Å²	18	53.1 Å²	53.1	9%	0.092	26%	0.256	C	S	.	.	H	α-helix	trans	-54.9	-48.4	173	-65.8	167.3	0	0	0	108.1	F346 L350 F356 L363 A387 R388 T394 F395	F346-I391 HydrophobicContact CE2-CD1 3.63Å; F346-I391 HydrophobicContact CE2-CG1 3.99Å; F346-I391 HydrophobicContact CZ-CD1 3.71Å; F346-I391 HydrophobicContact CZ-CG1 3.77Å; L350-I391 HydrophobicContact CD1-CG1 4.16Å; L350-I391 HydrophobicContact CD2-CG1 4.48Å; F356-I391 HydrophobicContact CD1-CG2 3.98Å; L363-I391 HydrophobicContact CD1-CD1 3.82Å; A387-I391 VanDerWaalsContact O-CG1 3.31Å; A387-I391 WeakPolarHBondContact O-CG1 3.36Å; A387-I391 PolarHBondContact O-N 2.87Å; R388-I391 PolarHBondContact O-N 3.48Å; I391-T394 PolarHBondContact O-N 2.91Å; I391-F395 VanDerWaalsContact O-CB 3.26Å; I391-F395 WeakPolarHBondContact O-CB 3.28Å; I391-F395 PolarHBondContact O-N 3.43Å
392	F	73.9	Confident	76.9	Confident	19 Å²	19	45.9 Å²	45.9	8%	0.083	22%	0.222	C	C	.	.	H	α-helix	trans	-70.3	-41.4	-178.6	-76.7	-62.7	0	0	0	113.6	R388 F390 T394 F395 C396 L407 L411 W421 L425	R388-F392 HydrophobicContact CB-CD2 4.48Å; R388-F392 WeakPolarHBondContact O-CD2 3.12Å; R388-F392 PolarHBondContact O-N 3.46Å; F390-F392 PolarHBondContact O-N 3.26Å; F392-T394 VanDerWaalsContact C-N 3.27Å; F392-T394 PolarHBondContact O-N 2.99Å; F392-F395 PolarHBondContact O-N 3.32Å; F392-C396 WeakPolarHBondContact O-CB 3.42Å; F392-C396 PolarHBondContact O-N 3.09Å; F392-C396 PolarHBondContact O-SG 2.81Å; F392-L407 HydrophobicContact CD1-CD2 3.53Å; F392-L407 HydrophobicContact CD1-CG 4.13Å; F392-L407 HydrophobicContact CE1-CD1 4.15Å; F392-L407 HydrophobicContact CE1-CD2 3Å; F392-L407 HydrophobicContact CE1-CG 3.38Å; F392-L407 HydrophobicContact CE2-CD2 4.1Å; F392-L407 HydrophobicContact CG-CD2 4.3Å; F392-L407 HydrophobicContact CZ-CD2 3.31Å; F392-L407 HydrophobicContact CZ-CG 3.93Å; F392-L411 HydrophobicContact CD2-CD1 4.39Å; F392-L411 HydrophobicContact CE2-CD1 3.49Å; F392-L411 VanDerWaalsContact CE2-CD1 3.49Å; F392-L411 HydrophobicContact CE2-CD2 3.66Å; F392-L411 HydrophobicContact CE2-CG 3.64Å; F392-L411 HydrophobicContact CZ-CD1 3.69Å; F392-L411 HydrophobicContact CZ-CD2 4.28Å; F392-L411 HydrophobicContact CZ-CG 3.8Å; F392-W421 HydrophobicContact CB-CH2 3.72Å; F392-W421 HydrophobicContact CB-CZ3 3.78Å; F392-W421 HydrophobicContact CD1-CZ3 4.4Å; F392-W421 HydrophobicContact CD2-CE3 4.45Å; F392-W421 AromaticContact CD2-CH2 3.17Å; F392-W421 HydrophobicContact CD2-CH2 3.17Å; F392-W421 HydrophobicContact CD2-CZ2 4.2Å; F392-W421 AromaticContact CD2-CZ3 3.3Å; F392-W421 HydrophobicContact CD2-CZ3 3.3Å; F392-W421 HydrophobicContact CE2-CH2 4.09Å; F392-W421 HydrophobicContact CE2-CZ3 4.06Å; F392-W421 AromaticContact CG-CH2 3.66Å; F392-W421 HydrophobicContact CG-CH2 3.66Å; F392-W421 AromaticContact CG-CZ3 3.52Å; F392-W421 HydrophobicContact CG-CZ3 3.52Å; F392-L425 HydrophobicContact CB-CD1 3.94Å
393	E	76	Confident	77	Confident	14 Å²	14	45 Å²	45	7%	0.065	22%	0.22	C	C	.	.	H	α-helix	trans	-59.6	-42.1	175.1	-169.5	-173.8	179.4	0	0	111.1	R322 L389 F390 R397	R322-E393 IonicContact CZ-OE1 3.27Å; R322-E393 IonicContact NE-OE1 3.46Å; R322-E393 IonicContact NH2-OE1 3.71Å; R322-E393 PolarHBondContact NH2-OE1 3.44Å; L389-E393 VanDerWaalsContact O-CB 3.23Å; L389-E393 WeakPolarHBondContact O-CB 3.04Å; L389-E393 PolarHBondContact O-N 3.31Å; F390-E393 PolarHBondContact O-N 2.91Å; E393-R397 VanDerWaalsContact O-CG 3.32Å; E393-R397 WeakPolarHBondContact O-CG 3.33Å; E393-R397 PolarHBondContact O-N 2.94Å; E393-R397 VanDerWaalsContact O-N 3.16Å; E393-R397 IonicContact OE1-CZ 3.12Å; E393-R397 IonicContact OE1-NE 3.98Å; E393-R397 IonicContact OE1-NH2 2.94Å; E393-R397 PolarHBondContact OE1-NH2 2.88Å; E393-R397 IonicContact OE2-NH2 3.92Å; E393-R397 PolarHBondContact OE2-NH2 2.89Å
394	T	78.1	Confident	76.8	Confident	7 Å²	7	45 Å²	45	4%	0.043	22%	0.221	C	C	.	.	H	α-helix	trans	-67.5	-42.2	177.1	-52.8	0	0	0	0	110.9	F354 F356 F390 I391 F392 C396 R397 I398	F354-T394 HydrophobicContact CD1-CG2 3.99Å; F354-T394 HydrophobicContact CE1-CG2 3.88Å; F356-T394 HydrophobicContact CE1-CG2 4.21Å; F356-T394 HydrophobicContact CZ-CG2 4.14Å; F390-T394 WeakPolarHBondContact O-CB 3.39Å; F390-T394 PolarHBondContact O-N 3.36Å; F390-T394 PolarHBondContact O-OG1 3.47Å; I391-T394 PolarHBondContact O-N 2.91Å; F392-T394 VanDerWaalsContact C-N 3.27Å; F392-T394 PolarHBondContact O-N 2.99Å; T394-C396 PolarHBondContact O-N 3.26Å; T394-R397 PolarHBondContact O-N 2.94Å; T394-I398 HydrophobicContact CG2-CD1 4.2Å; T394-I398 WeakPolarHBondContact O-CG1 3.39Å; T394-I398 PolarHBondContact O-N 3.34Å
395	F	76.8	Confident	76.6	Confident	28 Å²	28	49.1 Å²	49.1	12%	0.123	24%	0.243	C	C	.	.	H	α-helix	trans	-61.4	-44.8	177.1	-167.2	-96.5	0	0	0	112.2	F356 I391 F392 R397 I398 H399 I402 M406	F356-F395 HydrophobicContact CD1-CD2 4.28Å; F356-F395 AromaticContact CD2-CD2 3.92Å; F356-F395 HydrophobicContact CD2-CD2 3.92Å; F356-F395 HydrophobicContact CD2-CE2 4.33Å; F356-F395 HydrophobicContact CE1-CB 4.26Å; F356-F395 HydrophobicContact CE1-CD2 4.32Å; F356-F395 AromaticContact CE2-CD2 3.97Å; F356-F395 HydrophobicContact CE2-CD2 3.97Å; F356-F395 HydrophobicContact CG-CD2 4.08Å; F356-F395 HydrophobicContact CZ-CB 4.44Å; F356-F395 HydrophobicContact CZ-CD2 4.17Å; I391-F395 VanDerWaalsContact O-CB 3.26Å; I391-F395 WeakPolarHBondContact O-CB 3.28Å; I391-F395 PolarHBondContact O-N 3.43Å; F392-F395 PolarHBondContact O-N 3.32Å; F395-R397 VanDerWaalsContact C-N 3.31Å; F395-R397 PolarHBondContact O-N 3.04Å; F395-I398 PolarHBondContact O-N 3.01Å; F395-H399 AromaticContact CD2-CE1 3.75Å; F395-H399 AromaticContact CD2-ND1 3.63Å; F395-H399 HydrophobicContact CE1-CB 4.3Å; F395-H399 AromaticContact CE1-ND1 3.94Å; F395-H399 AromaticContact CE2-CE1 3.41Å; F395-H399 VanDerWaalsContact CE2-CE1 3.41Å; F395-H399 WeakPolarHBondContact CE2-CE1 3.39Å; F395-H399 AromaticContact CE2-ND1 3.52Å; F395-H399 AromaticContact CG-ND1 3.89Å; F395-H399 AromaticContact CZ-CE1 3.85Å; F395-H399 AromaticContact CZ-CG 3.96Å; F395-H399 AromaticContact CZ-ND1 3.67Å; F395-H399 PolarHBondContact O-N 2.85Å; F395-H399 PolarHBondContact O-ND1 3.23Å; F395-H399 VanDerWaalsContact O-ND1 3.12Å; F395-I402 HydrophobicContact CD1-CD1 4.01Å; F395-I402 HydrophobicContact CD1-CG1 4.14Å; F395-I402 HydrophobicContact CD1-CG2 4.36Å; F395-I402 HydrophobicContact CE1-CB 4.41Å; F395-I402 HydrophobicContact CE1-CD1 4.28Å; F395-I402 HydrophobicContact CE1-CG1 3.9Å; F395-I402 HydrophobicContact CE1-CG2 3.89Å; F395-M406 HydrophobicContact CZ-CE 3.9Å
396	C	72.4	Confident	76.5	Confident	19 Å²	19	47.6 Å²	47.6	13%	0.128	24%	0.237	C	C	.	.	H	α-helix	trans	-68.9	-23.3	178.5	-65.9	0	0	0	0	113.9	F392 T394 I402 M444	F392-C396 WeakPolarHBondContact O-CB 3.42Å; F392-C396 PolarHBondContact O-N 3.09Å; F392-C396 PolarHBondContact O-SG 2.81Å; T394-C396 PolarHBondContact O-N 3.26Å; C396-I402 HydrophobicContact CB-CD1 4.14Å; C396-I402 WeakPolarHBondContact SG-CD1 3.37Å; C396-M444 HydrophobicContact CB-CE 3.92Å; C396-M444 HydrophobicContact CB-SD 4.15Å
397	R	73	Confident	76.3	Confident	138 Å²	138	46.9 Å²	46.9	52%	0.521	23%	0.233	S	C	.	.	H	α-helix	trans	-77.2	-26.8	173.8	-73.2	-177.9	-146.8	155.8	2.8	112.8	E393 T394 F395	E393-R397 VanDerWaalsContact O-CG 3.32Å; E393-R397 WeakPolarHBondContact O-CG 3.33Å; E393-R397 PolarHBondContact O-N 2.94Å; E393-R397 VanDerWaalsContact O-N 3.16Å; E393-R397 IonicContact OE1-CZ 3.12Å; E393-R397 IonicContact OE1-NE 3.98Å; E393-R397 IonicContact OE1-NH2 2.94Å; E393-R397 PolarHBondContact OE1-NH2 2.88Å; E393-R397 IonicContact OE2-NH2 3.92Å; E393-R397 PolarHBondContact OE2-NH2 2.89Å; T394-R397 PolarHBondContact O-N 2.94Å; F395-R397 VanDerWaalsContact C-N 3.31Å; F395-R397 PolarHBondContact O-N 3.04Å
398	I	80.5	Confident	76.1	Confident	93 Å²	93	47 Å²	47	48%	0.477	23%	0.234	S	C	.	.	H	α-helix	trans	-92.2	-41.3	-176.8	-59.4	166.2	0	0	0	110.6	F354 F356 T394 F395	F354-I398 HydrophobicContact CD1-CD1 4.07Å; F356-I398 HydrophobicContact CE2-CD1 4.25Å; F356-I398 HydrophobicContact CZ-CD1 3.9Å; T394-I398 HydrophobicContact CG2-CD1 4.2Å; T394-I398 WeakPolarHBondContact O-CG1 3.39Å; T394-I398 PolarHBondContact O-N 3.34Å; F395-I398 PolarHBondContact O-N 3.01Å
399	H	78.3	Confident	76	Confident	72 Å²	72	49.7 Å²	49.7	33%	0.333	25%	0.253	S	S	.	.			trans	-100.1	132.2	-174.4	-59.9	86.3	0	0	0	111.7	F395 I402	F395-H399 AromaticContact CD2-CE1 3.75Å; F395-H399 AromaticContact CD2-ND1 3.63Å; F395-H399 HydrophobicContact CE1-CB 4.3Å; F395-H399 AromaticContact CE1-ND1 3.94Å; F395-H399 AromaticContact CE2-CE1 3.41Å; F395-H399 VanDerWaalsContact CE2-CE1 3.41Å; F395-H399 WeakPolarHBondContact CE2-CE1 3.39Å; F395-H399 AromaticContact CE2-ND1 3.52Å; F395-H399 AromaticContact CG-ND1 3.89Å; F395-H399 AromaticContact CZ-CE1 3.85Å; F395-H399 AromaticContact CZ-CG 3.96Å; F395-H399 AromaticContact CZ-ND1 3.67Å; F395-H399 PolarHBondContact O-N 2.85Å; F395-H399 PolarHBondContact O-ND1 3.23Å; F395-H399 VanDerWaalsContact O-ND1 3.12Å; H399-I402 HydrophobicContact CB-CG1 4.22Å
400	Q	72.7	Confident	75.7	Confident	122 Å²	122	50.4 Å²	50.4	57%	0.57	25%	0.254	S	S	*	.	S	Bend	trans	-83.3	-29.4	175.4	-68.8	-176.1	-7.6	0	0	112.9	V443 M444	Q400-V443 CarbonylContact O-C 3.17Å; Q400-V443 VanDerWaalsContact O-CA 3.32Å; Q400-V443 WeakPolarHBondContact O-CA 3.49Å; Q400-M444 PolarHBondContact O-N 2.94Å
401	C	73.4	Confident	75.4	Confident	85 Å²	85	50.4 Å²	50.4	57%	0.574	26%	0.255	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-124.4	127.8	179.3	-62.7	0	0	0	0	109.3	V442	C401-V442 WeakPolarHBondContact CA-O 3.46Å
402	I	77.9	Confident	74.9	Confident	5 Å²	5	55.3 Å²	55.3	3%	0.026	28%	0.281	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-127.2	129.5	-175.9	-57.5	172.2	0	0	0	108.7	F395 C396 H399 L407 H441 V442	F395-I402 HydrophobicContact CD1-CD1 4.01Å; F395-I402 HydrophobicContact CD1-CG1 4.14Å; F395-I402 HydrophobicContact CD1-CG2 4.36Å; F395-I402 HydrophobicContact CE1-CB 4.41Å; F395-I402 HydrophobicContact CE1-CD1 4.28Å; F395-I402 HydrophobicContact CE1-CG1 3.9Å; F395-I402 HydrophobicContact CE1-CG2 3.89Å; C396-I402 HydrophobicContact CB-CD1 4.14Å; C396-I402 WeakPolarHBondContact SG-CD1 3.37Å; H399-I402 HydrophobicContact CB-CG1 4.22Å; I402-L407 HydrophobicContact CG2-CD1 3.19Å; I402-H441 CarbonylContact O-C 3.55Å; I402-H441 VanDerWaalsContact O-CA 3.27Å; I402-H441 WeakPolarHBondContact O-CA 3.32Å; I402-V442 HydrophobicContact CB-CB 4.34Å; I402-V442 PolarHBondContact N-O 3.49Å; I402-V442 PolarHBondContact O-N 3.31Å
403	S	79.8	Confident	75	Confident	39 Å²	39	56.2 Å²	56.2	27%	0.273	29%	0.286	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-83.8	129.7	173.6	53.9	0	0	0	0	111.1	N405 M406 L407	S403-N405 VanDerWaalsContact C-N 3.3Å; S403-N405 PolarHBondContact O-N 3.31Å; S403-M406 WeakPolarHBondContact OG-CB 3.4Å; S403-L407 PolarHBondContact O-N 3.48Å
404	I	76.7	Confident	75.2	Confident	3 Å²	3	58.6 Å²	58.6	2%	0.015	30%	0.302	C	S	.	.	H	α-helix	trans	-67.3	-33.9	178.9	-64.9	170.5	0	0	0	110.8	L407 A408 P415 E419 I435 G440 V442	I404-L407 WeakPolarHBondContact O-CB 3.29Å; I404-L407 PolarHBondContact O-N 3.42Å; I404-A408 WeakPolarHBondContact O-CB 3.39Å; I404-A408 PolarHBondContact O-N 2.95Å; I404-P415 HydrophobicContact CG2-CB 4.23Å; I404-E419 HydrophobicContact CD1-CG 3.93Å; I404-E419 HydrophobicContact CG2-CG 4.35Å; I404-I435 HydrophobicContact CD1-CG2 4.46Å; I404-G440 WeakPolarHBondContact CG1-O 3.16Å; I404-G440 PolarHBondContact N-O 2.86Å; I404-V442 HydrophobicContact CD1-CG2 4.21Å; I404-V442 HydrophobicContact CG1-CG2 3.99Å
405	N	77.9	Confident	75.2	Confident	101 Å²	101	61.4 Å²	61.4	54%	0.54	32%	0.32	S	S	.	.	H	α-helix	trans	-64.5	-45.1	-179	-62.1	-20.4	0	0	0	112.5	S403 L407 A408 D409	S403-N405 VanDerWaalsContact C-N 3.3Å; S403-N405 PolarHBondContact O-N 3.31Å; N405-L407 PolarHBondContact O-N 2.94Å; N405-A408 PolarHBondContact O-N 2.88Å; N405-D409 WeakPolarHBondContact O-CB 3.43Å; N405-D409 VanDerWaalsContact O-CG 3.29Å; N405-D409 PolarHBondContact O-N 3.32Å
406	M	75.3	Confident	75.3	Confident	84 Å²	84	67 Å²	67	41%	0.414	35%	0.347	S	S	.	.	H	α-helix	trans	-64.8	-29	177.5	-164.2	-179	79.1	0	0	111.6	F395 S403 K410	F395-M406 HydrophobicContact CZ-CE 3.9Å; S403-M406 WeakPolarHBondContact OG-CB 3.4Å; M406-K410 HydrophobicContact CG-CD 4.35Å; M406-K410 VanDerWaalsContact O-CB 3.29Å; M406-K410 WeakPolarHBondContact O-CB 3.45Å; M406-K410 WeakPolarHBondContact O-CG 3.39Å; M406-K410 PolarHBondContact O-N 3.02Å
407	L	73.2	Confident	75.6	Confident	9 Å²	9	71 Å²	71	5%	0.047	36%	0.364	C	S	.	.	H	α-helix	trans	-70.8	-49.5	175.1	-114	137.1	0	0	0	112.2	F392 I402 S403 I404 N405 D409 K410 L411 I422	F392-L407 HydrophobicContact CD1-CD2 3.53Å; F392-L407 HydrophobicContact CD1-CG 4.13Å; F392-L407 HydrophobicContact CE1-CD1 4.15Å; F392-L407 HydrophobicContact CE1-CD2 3Å; F392-L407 HydrophobicContact CE1-CG 3.38Å; F392-L407 HydrophobicContact CE2-CD2 4.1Å; F392-L407 HydrophobicContact CG-CD2 4.3Å; F392-L407 HydrophobicContact CZ-CD2 3.31Å; F392-L407 HydrophobicContact CZ-CG 3.93Å; I402-L407 HydrophobicContact CG2-CD1 3.19Å; S403-L407 PolarHBondContact O-N 3.48Å; I404-L407 WeakPolarHBondContact O-CB 3.29Å; I404-L407 PolarHBondContact O-N 3.42Å; N405-L407 PolarHBondContact O-N 2.94Å; L407-D409 VanDerWaalsContact C-N 3.34Å; L407-D409 PolarHBondContact O-N 2.99Å; L407-K410 PolarHBondContact O-N 3.04Å; L407-L411 HydrophobicContact CD2-CD1 3.91Å; L407-L411 WeakPolarHBondContact O-CB 3.35Å; L407-L411 PolarHBondContact O-N 3.43Å; L407-I422 HydrophobicContact CD1-CD1 4.19Å; L407-I422 HydrophobicContact CD2-CD1 4.25Å; L407-I422 HydrophobicContact CD2-CG1 4.44Å
408	A	75	Confident	75.8	Confident	4 Å²	4	64.4 Å²	64.4	3%	0.033	34%	0.339	C	S	.	.	H	α-helix	trans	-58.8	-46.5	178.3	0	0	0	0	0	111	I404 N405 K410 L411 N412 M413 P415 A418	I404-A408 WeakPolarHBondContact O-CB 3.39Å; I404-A408 PolarHBondContact O-N 2.95Å; N405-A408 PolarHBondContact O-N 2.88Å; A408-K410 VanDerWaalsContact C-N 3.32Å; A408-K410 PolarHBondContact O-N 3.21Å; A408-L411 PolarHBondContact O-N 3.19Å; A408-N412 PolarHBondContact O-N 2.86Å; A408-M413 WeakPolarHBondContact CB-O 3.32Å; A408-M413 PolarHBondContact O-N 3.17Å; A408-M413 VanDerWaalsContact O-N 3.16Å; A408-P415 HydrophobicContact CB-CB 4.49Å; A408-P415 HydrophobicContact CB-CG 4.18Å; A408-A418 HydrophobicContact CB-CB 4.38Å
409	D	75.2	Confident	75.7	Confident	123 Å²	123	62.7 Å²	62.7	66%	0.658	33%	0.329	S	S	*	.	H	α-helix	trans	-63.8	-36.4	177	-69.3	-20.8	0	0	0	112.3	N405 L407 N412	N405-D409 WeakPolarHBondContact O-CB 3.43Å; N405-D409 VanDerWaalsContact O-CG 3.29Å; N405-D409 PolarHBondContact O-N 3.32Å; L407-D409 VanDerWaalsContact C-N 3.34Å; L407-D409 PolarHBondContact O-N 2.99Å; D409-N412 PolarHBondContact O-OD1 3.44Å
410	K	70.5	Confident	75.8	Confident	63 Å²	63	67.9 Å²	67.9	27%	0.274	35%	0.345	S	S	.	.	H	α-helix	trans	-76.4	-30.7	179.8	-77	-179.3	168.7	-82.1	0	113.1	D357 Q360 M406 L407 A408	D357-K410 IonicContact OD1-NZ 3.35Å; D357-K410 PolarHBondContact OD1-NZ 3.06Å; Q360-K410 PolarHBondContact NE2-O 2.72Å; Q360-K410 VanDerWaalsContact OE1-CD 3.32Å; M406-K410 HydrophobicContact CG-CD 4.35Å; M406-K410 VanDerWaalsContact O-CB 3.29Å; M406-K410 WeakPolarHBondContact O-CB 3.45Å; M406-K410 WeakPolarHBondContact O-CG 3.39Å; M406-K410 PolarHBondContact O-N 3.02Å; L407-K410 PolarHBondContact O-N 3.04Å; A408-K410 VanDerWaalsContact C-N 3.32Å; A408-K410 PolarHBondContact O-N 3.21Å
411	L	68.6	Low	76.1	Confident	12 Å²	12	64.1 Å²	64.1	6%	0.063	33%	0.326	C	S	.	.	H	α-helix	trans	-91.5	-3.4	-179.7	-80.4	172.7	0	0	0	113.7	R388 F392 L407 A408 M413 W421	R388-L411 HydrophobicContact CB-CD2 4.29Å; R388-L411 VanDerWaalsContact CD-CD2 3.5Å; R388-L411 HydrophobicContact CG-CD2 3.72Å; F392-L411 HydrophobicContact CD2-CD1 4.39Å; F392-L411 HydrophobicContact CE2-CD1 3.49Å; F392-L411 VanDerWaalsContact CE2-CD1 3.49Å; F392-L411 HydrophobicContact CE2-CD2 3.66Å; F392-L411 HydrophobicContact CE2-CG 3.64Å; F392-L411 HydrophobicContact CZ-CD1 3.69Å; F392-L411 HydrophobicContact CZ-CD2 4.28Å; F392-L411 HydrophobicContact CZ-CG 3.8Å; L407-L411 HydrophobicContact CD2-CD1 3.91Å; L407-L411 WeakPolarHBondContact O-CB 3.35Å; L407-L411 PolarHBondContact O-N 3.43Å; A408-L411 PolarHBondContact O-N 3.19Å; L411-M413 HydrophobicContact CB-CE 3.67Å; L411-M413 HydrophobicContact CB-CG 3.62Å; L411-M413 HydrophobicContact CB-SD 3.76Å; L411-M413 HydrophobicContact CD1-CE 3.81Å; L411-M413 HydrophobicContact CD1-CG 4.43Å; L411-M413 HydrophobicContact CD1-SD 3.57Å; L411-M413 VanDerWaalsContact CD1-SD 3.57Å; L411-M413 HydrophobicContact CD2-CE 4.23Å; L411-M413 HydrophobicContact CG-CE 4.13Å; L411-M413 HydrophobicContact CG-SD 4.28Å; L411-M413 PolarHBondContact O-N 3.42Å; L411-W421 HydrophobicContact CD1-CE3 4.29Å
412	N	67.9	Low	76.3	Confident	121 Å²	121	60.8 Å²	60.8	65%	0.647	30%	0.302	S	S	*	.	T	Hydrogen-bonded Turn	trans	51.7	38	-172	-62.3	11.8	0	0	0	112.3	R364 A408 D409	R364-N412 PolarHBondContact NH2-OD1 3.34Å; A408-N412 PolarHBondContact O-N 2.86Å; D409-N412 PolarHBondContact O-OD1 3.44Å
413	M	74.9	Confident	76.3	Confident	38 Å²	38	63.3 Å²	63.3	19%	0.187	32%	0.318	C	S	.	.	S	Bend	trans	-124.2	162.2	179.7	63	-177.2	48.9	0	0	110.6	A408 L411 E417 A418	A408-M413 WeakPolarHBondContact CB-O 3.32Å; A408-M413 PolarHBondContact O-N 3.17Å; A408-M413 VanDerWaalsContact O-N 3.16Å; L411-M413 HydrophobicContact CB-CE 3.67Å; L411-M413 HydrophobicContact CB-CG 3.62Å; L411-M413 HydrophobicContact CB-SD 3.76Å; L411-M413 HydrophobicContact CD1-CE 3.81Å; L411-M413 HydrophobicContact CD1-CG 4.43Å; L411-M413 HydrophobicContact CD1-SD 3.57Å; L411-M413 VanDerWaalsContact CD1-SD 3.57Å; L411-M413 HydrophobicContact CD2-CE 4.23Å; L411-M413 HydrophobicContact CG-CE 4.13Å; L411-M413 HydrophobicContact CG-SD 4.28Å; L411-M413 PolarHBondContact O-N 3.42Å; M413-E417 HydrophobicContact CB-CB 4.31Å; M413-A418 HydrophobicContact CG-CB 4.01Å; M413-A418 VanDerWaalsContact SD-CA 3.52Å; M413-A418 HydrophobicContact SD-CB 3.79Å
414	T	81.3	Confident	76.2	Confident	65 Å²	65	65.5 Å²	65.5	40%	0.399	33%	0.327	S	S	.	.			trans	-68.5	152.4	175.8	60.1	0	0	0	0	110.8	E416 E417 A418	T414-E416 PolarHBondContact O-N 3.02Å; T414-E417 PolarHBondContact N-OE2 2.69Å; T414-E417 PolarHBondContact O-N 2.92Å; T414-E417 VanDerWaalsContact O-N 3.13Å; T414-E417 WeakPolarHBondContact OG1-CB 3.43Å; T414-E417 VanDerWaalsContact OG1-CG 3.22Å; T414-E417 WeakPolarHBondContact OG1-CG 3.27Å; T414-E417 PolarHBondContact OG1-N 3.3Å; T414-E417 PolarHBondContact OG1-OE2 2.91Å; T414-A418 PolarHBondContact O-N 3.34Å
415	P	78.2	Confident	76.1	Confident	65 Å²	65	65.8 Å²	65.8	42%	0.422	33%	0.328	S	S	.	.	H	α-helix	trans	-55.7	-32.8	177.2	-25.1	33.7	0	0	0	113.3	I404 A408 A418 E419	I404-P415 HydrophobicContact CG2-CB 4.23Å; A408-P415 HydrophobicContact CB-CB 4.49Å; A408-P415 HydrophobicContact CB-CG 4.18Å; P415-A418 PolarHBondContact O-N 2.83Å; P415-E419 WeakPolarHBondContact O-CG 3.39Å; P415-E419 PolarHBondContact O-N 3.01Å
416	E	78.9	Confident	75.9	Confident	145 Å²	145	62.7 Å²	62.7	68%	0.678	31%	0.311	S	S	*	.	H	α-helix	trans	-72.8	-37.8	178.5	-70.3	172.6	149.8	0	0	112.7	T414 E419 R420	T414-E416 PolarHBondContact O-N 3.02Å; E416-E419 PolarHBondContact O-N 2.82Å; E416-R420 PolarHBondContact O-N 3.38Å; E416-R420 VanDerWaalsContact O-N 3.14Å
417	E	78.7	Confident	75.9	Confident	104 Å²	104	67.4 Å²	67.4	49%	0.486	32%	0.324	S	S	.	.	H	α-helix	trans	-69.1	-38.7	172.2	-73.3	166.6	154.9	0	0	111.2	M413 T414 E419 R420 W421	M413-E417 HydrophobicContact CB-CB 4.31Å; T414-E417 PolarHBondContact N-OE2 2.69Å; T414-E417 PolarHBondContact O-N 2.92Å; T414-E417 VanDerWaalsContact O-N 3.13Å; T414-E417 WeakPolarHBondContact OG1-CB 3.43Å; T414-E417 VanDerWaalsContact OG1-CG 3.22Å; T414-E417 WeakPolarHBondContact OG1-CG 3.27Å; T414-E417 PolarHBondContact OG1-N 3.3Å; T414-E417 PolarHBondContact OG1-OE2 2.91Å; E417-E419 VanDerWaalsContact C-N 3.33Å; E417-E419 PolarHBondContact O-N 3.45Å; E417-R420 PolarHBondContact O-N 3.41Å; E417-W421 VanDerWaalsContact O-CB 3.3Å; E417-W421 WeakPolarHBondContact O-CB 3.4Å; E417-W421 PolarHBondContact O-N 3.22Å
418	A	77.8	Confident	75.7	Confident	0 Å²	0	73.1 Å²	73.1	0%	0	36%	0.355	C	S	.	.	H	α-helix	trans	-60.4	-42.5	173.3	0	0	0	0	0	111.3	A408 M413 T414 P415 W421 I422	A408-A418 HydrophobicContact CB-CB 4.38Å; M413-A418 HydrophobicContact CG-CB 4.01Å; M413-A418 VanDerWaalsContact SD-CA 3.52Å; M413-A418 HydrophobicContact SD-CB 3.79Å; T414-A418 PolarHBondContact O-N 3.34Å; P415-A418 PolarHBondContact O-N 2.83Å; A418-W421 PolarHBondContact O-N 3.21Å; A418-I422 WeakPolarHBondContact O-CB 3.28Å; A418-I422 WeakPolarHBondContact O-CD1 3.49Å; A418-I422 WeakPolarHBondContact O-CG1 3.48Å; A418-I422 PolarHBondContact O-N 3.05Å
419	E	78.3	Confident	75.2	Confident	56 Å²	56	74.3 Å²	74.3	26%	0.262	36%	0.364	S	S	.	.	H	α-helix	trans	-60	-47.8	174.3	-80.6	-171	171.1	0	0	112	I404 P415 E416 E417 W421 I422 V423 S437	I404-E419 HydrophobicContact CD1-CG 3.93Å; I404-E419 HydrophobicContact CG2-CG 4.35Å; P415-E419 WeakPolarHBondContact O-CG 3.39Å; P415-E419 PolarHBondContact O-N 3.01Å; E416-E419 PolarHBondContact O-N 2.82Å; E417-E419 VanDerWaalsContact C-N 3.33Å; E417-E419 PolarHBondContact O-N 3.45Å; E419-W421 VanDerWaalsContact C-N 3.28Å; E419-W421 PolarHBondContact O-N 2.84Å; E419-I422 PolarHBondContact O-N 2.92Å; E419-V423 WeakPolarHBondContact O-CG2 3.46Å; E419-V423 PolarHBondContact O-N 3.48Å; E419-S437 PolarHBondContact OE1-OG 3.23Å
420	R	80.4	Confident	74.7	Confident	182 Å²	182	79.2 Å²	79.2	69%	0.687	37%	0.374	S	S	*	.	H	α-helix	trans	-60.4	-40.8	176.7	-72	-179.5	-174.2	163.7	5.3	111.8	E416 E417 V423 N424	E416-R420 PolarHBondContact O-N 3.38Å; E416-R420 VanDerWaalsContact O-N 3.14Å; E417-R420 PolarHBondContact O-N 3.41Å; R420-V423 PolarHBondContact O-N 3.5Å; R420-N424 PolarHBondContact O-N 2.98Å
421	W	78.6	Confident	74.6	Confident	43 Å²	43	77.8 Å²	77.8	16%	0.163	37%	0.369	C	S	.	.	H	α-helix	trans	-65	-43.5	178.3	-171	87	0	0	0	111.6	R388 L389 F392 L411 E417 A418 E419 V423 N424 L425	R388-W421 HydrophobicContact CB-CH2 4.34Å; R388-W421 HydrophobicContact CB-CZ2 3.86Å; L389-W421 HydrophobicContact CB-CZ2 4.48Å; L389-W421 HydrophobicContact CD2-CH2 3.96Å; L389-W421 HydrophobicContact CD2-CZ2 3.51Å; L389-W421 HydrophobicContact CG-CZ2 3.89Å; F392-W421 HydrophobicContact CB-CH2 3.72Å; F392-W421 HydrophobicContact CB-CZ3 3.78Å; F392-W421 HydrophobicContact CD1-CZ3 4.4Å; F392-W421 HydrophobicContact CD2-CE3 4.45Å; F392-W421 AromaticContact CD2-CH2 3.17Å; F392-W421 HydrophobicContact CD2-CH2 3.17Å; F392-W421 HydrophobicContact CD2-CZ2 4.2Å; F392-W421 AromaticContact CD2-CZ3 3.3Å; F392-W421 HydrophobicContact CD2-CZ3 3.3Å; F392-W421 HydrophobicContact CE2-CH2 4.09Å; F392-W421 HydrophobicContact CE2-CZ3 4.06Å; F392-W421 AromaticContact CG-CH2 3.66Å; F392-W421 HydrophobicContact CG-CH2 3.66Å; F392-W421 AromaticContact CG-CZ3 3.52Å; F392-W421 HydrophobicContact CG-CZ3 3.52Å; L411-W421 HydrophobicContact CD1-CE3 4.29Å; E417-W421 VanDerWaalsContact O-CB 3.3Å; E417-W421 WeakPolarHBondContact O-CB 3.4Å; E417-W421 PolarHBondContact O-N 3.22Å; A418-W421 PolarHBondContact O-N 3.21Å; E419-W421 VanDerWaalsContact C-N 3.28Å; E419-W421 PolarHBondContact O-N 2.84Å; W421-V423 PolarHBondContact O-N 3.45Å; W421-N424 PolarHBondContact O-N 3.49Å; W421-L425 HydrophobicContact CH2-CD1 3.76Å; W421-L425 HydrophobicContact CZ3-CD1 3.95Å; W421-L425 PolarHBondContact O-N 2.9Å
422	I	77.1	Confident	74.4	Confident	14 Å²	14	83 Å²	83	7%	0.072	40%	0.397	C	S	.	.	H	α-helix	trans	-62	-42.7	174.9	-68.5	162.3	0	0	0	111.1	L407 A418 E419 N424 L425 I426 I435 V442	L407-I422 HydrophobicContact CD1-CD1 4.19Å; L407-I422 HydrophobicContact CD2-CD1 4.25Å; L407-I422 HydrophobicContact CD2-CG1 4.44Å; A418-I422 WeakPolarHBondContact O-CB 3.28Å; A418-I422 WeakPolarHBondContact O-CD1 3.49Å; A418-I422 WeakPolarHBondContact O-CG1 3.48Å; A418-I422 PolarHBondContact O-N 3.05Å; E419-I422 PolarHBondContact O-N 2.92Å; I422-N424 VanDerWaalsContact C-N 3.34Å; I422-N424 PolarHBondContact O-N 2.94Å; I422-L425 WeakPolarHBondContact O-CB 3.47Å; I422-L425 PolarHBondContact O-N 3.46Å; I422-I426 HydrophobicContact CG2-CD1 3.76Å; I422-I426 HydrophobicContact CG2-CG1 4.4Å; I422-I426 WeakPolarHBondContact O-CG1 3.45Å; I422-I426 PolarHBondContact O-N 3.41Å; I422-I435 HydrophobicContact CG2-CD1 4.35Å; I422-V442 HydrophobicContact CD1-CG2 4.3Å; I422-V442 HydrophobicContact CG2-CG2 4.44Å
423	V	78.4	Confident	74.5	Confident	59 Å²	59	78.6 Å²	78.6	36%	0.358	38%	0.377	S	S	.	.	H	α-helix	trans	-62.4	-41.9	177.1	171.2	0	0	0	0	111.2	E419 R420 W421 L425 I426 R427 I435	E419-V423 WeakPolarHBondContact O-CG2 3.46Å; E419-V423 PolarHBondContact O-N 3.48Å; R420-V423 PolarHBondContact O-N 3.5Å; W421-V423 PolarHBondContact O-N 3.45Å; V423-L425 VanDerWaalsContact C-N 3.32Å; V423-L425 PolarHBondContact O-N 2.9Å; V423-I426 PolarHBondContact O-N 2.89Å; V423-R427 WeakPolarHBondContact O-CB 3.01Å; V423-R427 PolarHBondContact O-N 3.13Å; V423-I435 HydrophobicContact CG2-CD1 3.65Å
424	N	78.3	Confident	74.6	Confident	85 Å²	85	83.8 Å²	83.8	46%	0.455	40%	0.399	S	S	.	.	H	α-helix	trans	-62.9	-39.3	174.5	-76.4	-19.1	0	0	0	111.7	R420 W421 I422 R427 N428	R420-N424 PolarHBondContact O-N 2.98Å; W421-N424 PolarHBondContact O-N 3.49Å; I422-N424 VanDerWaalsContact C-N 3.34Å; I422-N424 PolarHBondContact O-N 2.94Å; N424-R427 PolarHBondContact O-N 2.85Å; N424-N428 WeakPolarHBondContact O-CB 3.37Å; N424-N428 VanDerWaalsContact O-CG 3.22Å; N424-N428 PolarHBondContact O-N 3.48Å; N424-N428 PolarHBondContact O-ND2 3.3Å
425	L	73.9	Confident	74.3	Confident	9 Å²	9	83.4 Å²	83.4	5%	0.047	39%	0.394	C	S	.	.	H	α-helix	trans	-63.9	-46	174.9	178.7	142.9	0	0	0	111.9	L389 F392 W421 I422 V423 R427 N428 A429 L431	L389-L425 HydrophobicContact CD2-CB 4.16Å; L389-L425 HydrophobicContact CD2-CD1 3.73Å; L389-L425 HydrophobicContact CD2-CG 4.26Å; F392-L425 HydrophobicContact CB-CD1 3.94Å; W421-L425 HydrophobicContact CH2-CD1 3.76Å; W421-L425 HydrophobicContact CZ3-CD1 3.95Å; W421-L425 PolarHBondContact O-N 2.9Å; I422-L425 WeakPolarHBondContact O-CB 3.47Å; I422-L425 PolarHBondContact O-N 3.46Å; V423-L425 VanDerWaalsContact C-N 3.32Å; V423-L425 PolarHBondContact O-N 2.9Å; L425-R427 VanDerWaalsContact C-N 3.33Å; L425-R427 PolarHBondContact O-N 2.98Å; L425-N428 PolarHBondContact O-N 2.92Å; L425-A429 WeakPolarHBondContact O-CB 3.23Å; L425-A429 PolarHBondContact O-N 3.31Å; L425-L431 HydrophobicContact CD2-CD1 4.14Å
426	I	73.6	Confident	74.3	Confident	35 Å²	35	83.2 Å²	83.2	18%	0.179	39%	0.389	C	S	.	.	H	α-helix	trans	-61.1	-43.4	177.3	-70.9	162.6	0	0	0	110.8	I422 V423 N428 R430 L431 A433 I435	I422-I426 HydrophobicContact CG2-CD1 3.76Å; I422-I426 HydrophobicContact CG2-CG1 4.4Å; I422-I426 WeakPolarHBondContact O-CG1 3.45Å; I422-I426 PolarHBondContact O-N 3.41Å; V423-I426 PolarHBondContact O-N 2.89Å; I426-N428 VanDerWaalsContact C-N 3.34Å; I426-N428 PolarHBondContact O-N 2.91Å; I426-R430 WeakPolarHBondContact O-CA 3.43Å; I426-R430 PolarHBondContact O-N 2.94Å; I426-L431 VanDerWaalsContact CG2-O 3.31Å; I426-L431 WeakPolarHBondContact CG2-O 3.44Å; I426-A433 HydrophobicContact CD1-CB 3.73Å; I426-A433 HydrophobicContact CG1-CB 4.07Å; I426-I435 HydrophobicContact CD1-CD1 4.12Å; I426-I435 HydrophobicContact CD1-CG1 4.38Å
427	R	74.3	Confident	73.8	Confident	184 Å²	184	80 Å²	80	69%	0.694	38%	0.383	S	S	*	.	H	α-helix	trans	-63	-40.4	178.7	-171.9	179.2	-75	172.7	-3.3	111.9	V423 N424 L425	V423-R427 WeakPolarHBondContact O-CB 3.01Å; V423-R427 PolarHBondContact O-N 3.13Å; N424-R427 PolarHBondContact O-N 2.85Å; L425-R427 VanDerWaalsContact C-N 3.33Å; L425-R427 PolarHBondContact O-N 2.98Å
428	N	69.5	Low	73.6	Confident	128 Å²	128	85.1 Å²	85.1	68%	0.684	40%	0.403	S	S	*	.	H	α-helix	trans	-78.4	-39.5	-179.8	-69.8	-15.4	0	0	0	112.8	N424 L425 I426	N424-N428 WeakPolarHBondContact O-CB 3.37Å; N424-N428 VanDerWaalsContact O-CG 3.22Å; N424-N428 PolarHBondContact O-N 3.48Å; N424-N428 PolarHBondContact O-ND2 3.3Å; L425-N428 PolarHBondContact O-N 2.92Å; I426-N428 VanDerWaalsContact C-N 3.34Å; I426-N428 PolarHBondContact O-N 2.91Å
429	A	63.9	Low	73.3	Confident	29 Å²	29	91.3 Å²	91.3	24%	0.24	44%	0.436	C	S	.	.	H	α-helix	trans	-87.4	-9.3	-175.7	0	0	0	0	0	114	L425 L431	L425-A429 WeakPolarHBondContact O-CB 3.23Å; L425-A429 PolarHBondContact O-N 3.31Å; A429-L431 VanDerWaalsContact C-N 3.25Å; A429-L431 HydrophobicContact CB-CD1 3.73Å; A429-L431 HydrophobicContact CB-CG 3.86Å; A429-L431 PolarHBondContact O-N 3.33Å
430	R	65	Low	73	Confident	227 Å²	227	89.4 Å²	89.4	86%	0.857	43%	0.431	S	S	*	.	T	Hydrogen-bonded Turn	trans	49.2	47	-174.2	-61.8	-174.8	178	-169.1	-1.8	112	I426	I426-R430 WeakPolarHBondContact O-CA 3.43Å; I426-R430 PolarHBondContact O-N 2.94Å
431	L	68.2	Low	72.9	Confident	32 Å²	32	84.6 Å²	84.6	17%	0.168	42%	0.417	C	S	.	.			trans	-90.4	132.3	176	-70.5	164.7	0	0	0	109.1	L425 I426 A429 A433 M444	L425-L431 HydrophobicContact CD2-CD1 4.14Å; I426-L431 VanDerWaalsContact CG2-O 3.31Å; I426-L431 WeakPolarHBondContact CG2-O 3.44Å; A429-L431 VanDerWaalsContact C-N 3.25Å; A429-L431 HydrophobicContact CB-CD1 3.73Å; A429-L431 HydrophobicContact CB-CG 3.86Å; A429-L431 PolarHBondContact O-N 3.33Å; L431-A433 PolarHBondContact O-N 2.99Å; L431-A433 VanDerWaalsContact O-N 3.11Å; L431-M444 HydrophobicContact CB-CE 3.99Å; L431-M444 HydrophobicContact CD1-CE 4.23Å; L431-M444 HydrophobicContact CD2-CE 4.35Å; L431-M444 HydrophobicContact CG-CE 4.42Å
432	D	64.7	Low	72.8	Confident	121 Å²	121	82.8 Å²	82.8	65%	0.647	41%	0.41	S	S	*	.			trans	-78	98.3	173.6	-65.9	-39.4	0	0	0	108.4	G445	D432-G445 WeakPolarHBondContact O-CA 3.31Å; D432-G445 PolarHBondContact O-N 3.41Å
433	A	70.8	Confident	72.8	Confident	29 Å²	29	84.5 Å²	84.5	24%	0.24	42%	0.421	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-131.7	143.7	-179.9	0	0	0	0	0	110.5	I426 L431 V442 M444	I426-A433 HydrophobicContact CD1-CB 3.73Å; I426-A433 HydrophobicContact CG1-CB 4.07Å; L431-A433 PolarHBondContact O-N 2.99Å; L431-A433 VanDerWaalsContact O-N 3.11Å; A433-V442 HydrophobicContact CB-CG1 4.34Å; A433-M444 HydrophobicContact CB-CE 4.05Å; A433-M444 HydrophobicContact CB-SD 3.48Å; A433-M444 WeakPolarHBondContact CB-SD 3.21Å
434	K	76.3	Confident	72.6	Confident	147 Å²	147	82.9 Å²	82.9	64%	0.639	41%	0.41	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-114.4	124.7	177.7	-165.9	169.2	-178.1	178.5	0	109	V443	K434-V443 PolarHBondContact N-O 3.38Å; K434-V443 PolarHBondContact O-N 3.35Å
435	I	75.9	Confident	72.2	Confident	57 Å²	57	80.5 Å²	80.5	29%	0.292	41%	0.405	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-97.5	115.7	-178.8	-56.7	172.9	0	0	0	108.2	I404 I422 V423 I426 S437 V442	I404-I435 HydrophobicContact CD1-CG2 4.46Å; I422-I435 HydrophobicContact CG2-CD1 4.35Å; V423-I435 HydrophobicContact CG2-CD1 3.65Å; I426-I435 HydrophobicContact CD1-CD1 4.12Å; I426-I435 HydrophobicContact CD1-CG1 4.38Å; I435-S437 PolarHBondContact O-N 3.47Å; I435-V442 HydrophobicContact CG1-CG1 4.26Å; I435-V442 HydrophobicContact CG1-CG2 4.28Å; I435-V442 HydrophobicContact CG2-CG2 4.35Å
436	D	76.9	Confident	71.6	Confident	62 Å²	62	85.8 Å²	85.8	33%	0.332	43%	0.434	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-97.9	79.3	173.9	-69.6	-43.2	0	0	0	109.4	K438 L439 G440 H441	D436-K438 PolarHBondContact O-N 2.98Å; D436-K438 VanDerWaalsContact O-N 3.12Å; D436-L439 PolarHBondContact O-N 2.89Å; D436-L439 VanDerWaalsContact O-N 3.1Å; D436-G440 PolarHBondContact O-N 3.37Å; D436-G440 VanDerWaalsContact O-N 3.09Å; D436-H441 WeakPolarHBondContact CA-O 3.33Å; D436-H441 WeakPolarHBondContact CB-O 3.44Å; D436-H441 PolarHBondContact N-O 3.47Å; D436-H441 PolarHBondContact O-N 2.7Å
437	S	69.8	Low	71.1	Confident	77 Å²	77	90.1 Å²	90.1	54%	0.538	46%	0.457	S	S	.	.	T	Hydrogen-bonded Turn	trans	-57.6	-27.7	-178	-174.8	0	0	0	0	113.1	E419 I435 L439 G440	E419-S437 PolarHBondContact OE1-OG 3.23Å; I435-S437 PolarHBondContact O-N 3.47Å; S437-L439 VanDerWaalsContact C-N 3.35Å; S437-L439 PolarHBondContact O-N 3.34Å; S437-G440 PolarHBondContact O-N 3Å
438	K	73.8	Confident	70.7	Confident	211 Å²	211	84.9 Å²	84.9	92%	0.917	45%	0.454	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.8	-30.8	177.6	-66.6	-174.4	-179.8	-178	0	114.4	D436	D436-K438 PolarHBondContact O-N 2.98Å; D436-K438 VanDerWaalsContact O-N 3.12Å
439	L	71.1	Confident	70.8	Confident	131 Å²	131	82.9 Å²	82.9	69%	0.686	45%	0.446	S	S	*	.	T	Hydrogen-bonded Turn	trans	-106.5	-2.8	179.8	-68.5	169.6	0	0	0	111.7	D436 S437 H441	D436-L439 PolarHBondContact O-N 2.89Å; D436-L439 VanDerWaalsContact O-N 3.1Å; S437-L439 VanDerWaalsContact C-N 3.35Å; S437-L439 PolarHBondContact O-N 3.34Å; L439-H441 VanDerWaalsContact C-N 3.25Å; L439-H441 PolarHBondContact O-CD2 3.02Å; L439-H441 PolarHBondContact O-N 3.37Å
440	G	72.3	Confident	71.6	Confident	16 Å²	16	84.1 Å²	84.1	17%	0.165	45%	0.452	C	S	.	.	T	Hydrogen-bonded Turn	trans	66	28.2	-175.7	0	0	0	0	0	113	I404 D436 S437	I404-G440 WeakPolarHBondContact CG1-O 3.16Å; I404-G440 PolarHBondContact N-O 2.86Å; D436-G440 PolarHBondContact O-N 3.37Å; D436-G440 VanDerWaalsContact O-N 3.09Å; S437-G440 PolarHBondContact O-N 3Å
441	H	78.1	Confident	72.7	Confident	81 Å²	81	77.7 Å²	77.7	38%	0.375	44%	0.44	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-119.2	137.1	-177.6	-67.7	-51.2	0	0	0	112.1	I402 D436 L439	I402-H441 CarbonylContact O-C 3.55Å; I402-H441 VanDerWaalsContact O-CA 3.27Å; I402-H441 WeakPolarHBondContact O-CA 3.32Å; D436-H441 WeakPolarHBondContact CA-O 3.33Å; D436-H441 WeakPolarHBondContact CB-O 3.44Å; D436-H441 PolarHBondContact N-O 3.47Å; D436-H441 PolarHBondContact O-N 2.7Å; L439-H441 VanDerWaalsContact C-N 3.25Å; L439-H441 PolarHBondContact O-CD2 3.02Å; L439-H441 PolarHBondContact O-N 3.37Å
442	V	77.2	Confident	73.6	Confident	4 Å²	4	84.9 Å²	84.9	2%	0.024	47%	0.466	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-101.3	118.7	167.4	-176.2	0	0	0	0	107.6	C401 I402 I404 I422 A433 I435 M444	C401-V442 WeakPolarHBondContact CA-O 3.46Å; I402-V442 HydrophobicContact CB-CB 4.34Å; I402-V442 PolarHBondContact N-O 3.49Å; I402-V442 PolarHBondContact O-N 3.31Å; I404-V442 HydrophobicContact CD1-CG2 4.21Å; I404-V442 HydrophobicContact CG1-CG2 3.99Å; I422-V442 HydrophobicContact CD1-CG2 4.3Å; I422-V442 HydrophobicContact CG2-CG2 4.44Å; A433-V442 HydrophobicContact CB-CG1 4.34Å; I435-V442 HydrophobicContact CG1-CG1 4.26Å; I435-V442 HydrophobicContact CG1-CG2 4.28Å; I435-V442 HydrophobicContact CG2-CG2 4.35Å; V442-M444 HydrophobicContact CG1-SD 4.49Å
443	V	77.6	Confident	74.5	Confident	50 Å²	50	83.8 Å²	83.8	30%	0.303	46%	0.457	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-103.3	117.5	177.5	-177.1	0	0	0	0	108.8	Q400 K434	Q400-V443 CarbonylContact O-C 3.17Å; Q400-V443 VanDerWaalsContact O-CA 3.32Å; Q400-V443 WeakPolarHBondContact O-CA 3.49Å; K434-V443 PolarHBondContact N-O 3.38Å; K434-V443 PolarHBondContact O-N 3.35Å
444	M	73.9	Confident	75.1	Confident	25 Å²	25	86.9 Å²	86.9	12%	0.123	47%	0.467	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-74.1	137.8	175.2	-58.3	-62	-69.8	0	0	109.7	C396 Q400 L431 A433 V442 N446	C396-M444 HydrophobicContact CB-CE 3.92Å; C396-M444 HydrophobicContact CB-SD 4.15Å; Q400-M444 PolarHBondContact O-N 2.94Å; L431-M444 HydrophobicContact CB-CE 3.99Å; L431-M444 HydrophobicContact CD1-CE 4.23Å; L431-M444 HydrophobicContact CD2-CE 4.35Å; L431-M444 HydrophobicContact CG-CE 4.42Å; A433-M444 HydrophobicContact CB-CE 4.05Å; A433-M444 HydrophobicContact CB-SD 3.48Å; A433-M444 WeakPolarHBondContact CB-SD 3.21Å; V442-M444 HydrophobicContact CG1-SD 4.49Å; M444-N446 PolarHBondContact O-N 3.25Å
445	G	69.4	Low	75.8	Confident	35 Å²	35	84 Å²	84	36%	0.361	46%	0.462	S	S	.	.	P	Polyproline II helix	trans	-60	132.8	173.1	0	0	0	0	0	110.2	D432 N447	D432-G445 WeakPolarHBondContact O-CA 3.31Å; D432-G445 PolarHBondContact O-N 3.41Å; G445-N447 PolarHBondContact O-N 2.82Å
446	N	62.5	Low	76.4	Confident	121 Å²	121	85.8 Å²	85.8	65%	0.647	47%	0.471	S	S	*	.			trans	-70.1	107.6	-177.9	-165	9.9	0	0	0	109.9	M444 A448	M444-N446 PolarHBondContact O-N 3.25Å; N446-A448 PolarHBondContact O-N 2.97Å
447	N	63.1	Low	76.8	Confident	125 Å²	125	89 Å²	89	67%	0.668	48%	0.484	S	S	*	.			trans	-77.6	47	176.9	-73.7	-20.2	0	0	0	112.2	G445 V449	G445-N447 PolarHBondContact O-N 2.82Å; N447-V449 PolarHBondContact O-N 2.85Å
448	A	64.1	Low	77.7	Confident	75 Å²	75	92.1 Å²	92.1	62%	0.62	49%	0.488	S	S	*	.			trans	-73.9	93.6	173.5	0	0	0	0	0	109	N446 S450	N446-A448 PolarHBondContact O-N 2.97Å; A448-S450 PolarHBondContact O-N 3.17Å; A448-S450 VanDerWaalsContact O-N 3.07Å
449	V	72.4	Confident	78.4	Confident	86 Å²	86	85.8 Å²	85.8	52%	0.521	47%	0.467	S	S	.	.			trans	-66.2	111.1	171.2	-174.7	0	0	0	0	107.7	N447 Q453 Q454	N447-V449 PolarHBondContact O-N 2.85Å; V449-Q453 HydrophobicContact CG1-CB 4.23Å; V449-Q453 HydrophobicContact CG1-CG 4.5Å; V449-Q454 HydrophobicContact CG1-CG 3.91Å
450	S	80.6	Confident	79.4	Confident	54 Å²	54	87.2 Å²	87.2	38%	0.378	47%	0.467	S	S	.	.			trans	-57.4	136.8	178.1	178	0	0	0	0	110.8	A448 Y452 Q453 Q454	A448-S450 PolarHBondContact O-N 3.17Å; A448-S450 VanDerWaalsContact O-N 3.07Å; S450-Y452 PolarHBondContact O-N 2.98Å; S450-Y452 VanDerWaalsContact O-N 3.12Å; S450-Y452 WeakPolarHBondContact OG-CD2 3.45Å; S450-Y452 PolarHBondContact OG-N 3.45Å; S450-Q453 WeakPolarHBondContact O-CB 3.49Å; S450-Q453 PolarHBondContact O-N 3.44Å; S450-Q454 PolarHBondContact O-N 3Å
451	P	87.5	Confident	80.2	Confident	93 Å²	93	89.2 Å²	89.2	60%	0.604	48%	0.479	S	S	*	.	H	α-helix	trans	-52.8	-34	174.7	-27.3	34.6	0	0	0	113	Q453 Q454 V455	P451-Q453 VanDerWaalsContact C-N 3.32Å; P451-Q453 PolarHBondContact O-N 3.3Å; P451-Q454 PolarHBondContact O-N 3.1Å; P451-V455 WeakPolarHBondContact O-CG2 3.46Å; P451-V455 PolarHBondContact O-N 3.15Å
452	Y	87.2	Confident	80.9	Confident	182 Å²	182	90.6 Å²	90.6	71%	0.714	49%	0.488	S	S	*	.	H	α-helix	trans	-61.3	-39.3	175.6	-63.6	-70.2	0	0	0	112.4	S450 V455 I456	S450-Y452 PolarHBondContact O-N 2.98Å; S450-Y452 VanDerWaalsContact O-N 3.12Å; S450-Y452 WeakPolarHBondContact OG-CD2 3.45Å; S450-Y452 PolarHBondContact OG-N 3.45Å; Y452-V455 PolarHBondContact O-N 3.09Å; Y452-I456 WeakPolarHBondContact O-CD1 3.28Å; Y452-I456 VanDerWaalsContact O-CG1 3.23Å; Y452-I456 WeakPolarHBondContact O-CG1 3.45Å; Y452-I456 PolarHBondContact O-N 3.18Å
453	Q	83.9	Confident	81.6	Confident	98 Å²	98	93.9 Å²	93.9	46%	0.458	51%	0.511	S	S	.	.	H	α-helix	trans	-65.5	-40.2	177.7	-166.7	68.9	8.6	0	0	111.3	V449 S450 P451 V455 I456 E457	V449-Q453 HydrophobicContact CG1-CB 4.23Å; V449-Q453 HydrophobicContact CG1-CG 4.5Å; S450-Q453 WeakPolarHBondContact O-CB 3.49Å; S450-Q453 PolarHBondContact O-N 3.44Å; P451-Q453 VanDerWaalsContact C-N 3.32Å; P451-Q453 PolarHBondContact O-N 3.3Å; Q453-V455 PolarHBondContact O-N 3.45Å; Q453-I456 PolarHBondContact O-N 3.31Å; Q453-E457 PolarHBondContact O-N 3.39Å
454	Q	84.3	Confident	82.3	Confident	95 Å²	95	97.4 Å²	97.4	44%	0.444	52%	0.523	S	S	.	.	H	α-helix	trans	-65.1	-38.9	175.9	-65.2	-176.3	3.2	0	0	112.2	V449 S450 P451 E457 K458	V449-Q454 HydrophobicContact CG1-CG 3.91Å; S450-Q454 PolarHBondContact O-N 3Å; P451-Q454 PolarHBondContact O-N 3.1Å; Q454-E457 PolarHBondContact O-N 3.04Å; Q454-K458 WeakPolarHBondContact O-CG 3.49Å; Q454-K458 PolarHBondContact O-N 3.21Å; Q454-K458 VanDerWaalsContact O-N 3.11Å
455	V	89.9	Confident	83.2	Confident	87 Å²	87	104.6 Å²	104.6	53%	0.527	55%	0.549	S	S	.	.	H	α-helix	trans	-64.6	-42.8	175.1	173.8	0	0	0	0	110.3	P451 Y452 Q453 K458 T459	P451-V455 WeakPolarHBondContact O-CG2 3.46Å; P451-V455 PolarHBondContact O-N 3.15Å; Y452-V455 PolarHBondContact O-N 3.09Å; Q453-V455 PolarHBondContact O-N 3.45Å; V455-K458 PolarHBondContact O-N 3.28Å; V455-T459 VanDerWaalsContact O-CB 3.22Å; V455-T459 WeakPolarHBondContact O-CB 3.41Å; V455-T459 PolarHBondContact O-N 3.4Å; V455-T459 PolarHBondContact O-OG1 2.75Å
456	I	88.4	Confident	84.3	Confident	94 Å²	94	106.4 Å²	106.4	48%	0.482	56%	0.556	S	S	.	*	H	α-helix	trans	-62.8	-45.9	177.4	-68.6	163.1	0	0	0	110.8	Y452 Q453 K458 T459 K460	Y452-I456 WeakPolarHBondContact O-CD1 3.28Å; Y452-I456 VanDerWaalsContact O-CG1 3.23Å; Y452-I456 WeakPolarHBondContact O-CG1 3.45Å; Y452-I456 PolarHBondContact O-N 3.18Å; Q453-I456 PolarHBondContact O-N 3.31Å; I456-K458 PolarHBondContact O-N 3.47Å; I456-T459 PolarHBondContact O-N 2.92Å; I456-K460 VanDerWaalsContact O-CB 3.27Å; I456-K460 WeakPolarHBondContact O-CB 3.47Å; I456-K460 PolarHBondContact O-N 3.1Å
457	E	86.6	Confident	85.6	Confident	128 Å²	128	106.3 Å²	106.3	60%	0.598	55%	0.551	S	S	*	*	H	α-helix	trans	-59.6	-46.7	178.5	-80.4	-176.4	169.2	0	0	112.3	Q453 Q454	Q453-E457 PolarHBondContact O-N 3.39Å; Q454-E457 PolarHBondContact O-N 3.04Å
458	K	86.8	Confident	87	Confident	144 Å²	144	104.3 Å²	104.3	63%	0.626	54%	0.539	S	S	*	.	H	α-helix	trans	-63.1	-47	176.4	-70.8	178.6	-179.5	177.9	0	111	Q454 V455 I456 K460 S461 L462	Q454-K458 WeakPolarHBondContact O-CG 3.49Å; Q454-K458 PolarHBondContact O-N 3.21Å; Q454-K458 VanDerWaalsContact O-N 3.11Å; V455-K458 PolarHBondContact O-N 3.28Å; I456-K458 PolarHBondContact O-N 3.47Å; K458-K460 PolarHBondContact O-N 3.3Å; K458-S461 PolarHBondContact O-N 3.3Å; K458-S461 PolarHBondContact O-OG 3.26Å; K458-L462 VanDerWaalsContact O-CD1 3.24Å; K458-L462 WeakPolarHBondContact O-CD1 3.43Å; K458-L462 PolarHBondContact O-N 3.43Å
459	T	90.3	Very high	88.3	Confident	77 Å²	77	105.7 Å²	105.7	47%	0.472	54%	0.536	S	S	.	.	H	α-helix	trans	-68.8	-33.2	-176	-53	0	0	0	0	112.7	V455 I456 S461 L462 S463	V455-T459 VanDerWaalsContact O-CB 3.22Å; V455-T459 WeakPolarHBondContact O-CB 3.41Å; V455-T459 PolarHBondContact O-N 3.4Å; V455-T459 PolarHBondContact O-OG1 2.75Å; I456-T459 PolarHBondContact O-N 2.92Å; T459-S461 VanDerWaalsContact C-N 3.33Å; T459-S461 PolarHBondContact O-N 2.69Å; T459-L462 PolarHBondContact O-N 3.49Å; T459-S463 WeakPolarHBondContact O-CB 3.39Å; T459-S463 PolarHBondContact O-N 2.94Å
460	K	91.2	Very high	89.3	Confident	161 Å²	161	104.3 Å²	104.3	70%	0.7	53%	0.533	S	S	*	.	H	α-helix	trans	-61	-41.7	179.7	-167.6	172.4	-174	176.5	0	112.1	I456 K458 F464	I456-K460 VanDerWaalsContact O-CB 3.27Å; I456-K460 WeakPolarHBondContact O-CB 3.47Å; I456-K460 PolarHBondContact O-N 3.1Å; K458-K460 PolarHBondContact O-N 3.3Å; K460-F464 PolarHBondContact O-N 3.41Å; K460-F464 VanDerWaalsContact O-N 3.15Å
461	S	89.6	Confident	89.8	Confident	59 Å²	59	106 Å²	106	41%	0.413	54%	0.536	S	S	.	.	H	α-helix	trans	-67.1	-39.9	176.5	74.7	0	0	0	0	112.4	K458 T459 R465	K458-S461 PolarHBondContact O-N 3.3Å; K458-S461 PolarHBondContact O-OG 3.26Å; T459-S461 VanDerWaalsContact C-N 3.33Å; T459-S461 PolarHBondContact O-N 2.69Å; S461-R465 WeakPolarHBondContact O-CB 3.25Å; S461-R465 WeakPolarHBondContact O-CG 3.18Å; S461-R465 PolarHBondContact O-N 2.93Å; S461-R465 VanDerWaalsContact O-N 3.09Å
462	L	92.6	Very high	90	Very high	109 Å²	109	106 Å²	106	57%	0.571	53%	0.531	S	S	*	.	H	α-helix	trans	-66.7	-48.3	176.1	-89.9	100.2	0	0	0	111.6	K458 T459 F464 R465 S466	K458-L462 VanDerWaalsContact O-CD1 3.24Å; K458-L462 WeakPolarHBondContact O-CD1 3.43Å; K458-L462 PolarHBondContact O-N 3.43Å; T459-L462 PolarHBondContact O-N 3.49Å; L462-F464 VanDerWaalsContact C-N 3.31Å; L462-F464 PolarHBondContact O-N 3.44Å; L462-R465 PolarHBondContact O-N 3.15Å; L462-R465 VanDerWaalsContact O-N 3.14Å; L462-S466 WeakPolarHBondContact O-CB 3.31Å; L462-S466 PolarHBondContact O-N 3.09Å; L462-S466 PolarHBondContact O-OG 2.94Å
463	S	92	Very high	90.2	Very high	73 Å²	73	102 Å²	102	51%	0.51	52%	0.521	S	S	.	.	H	α-helix	trans	-55.8	-46.2	179.2	174.3	0	0	0	0	111.4	T459 S466 Q467	T459-S463 WeakPolarHBondContact O-CB 3.39Å; T459-S463 PolarHBondContact O-N 2.94Å; S463-S466 PolarHBondContact O-N 3.01Å; S463-Q467 WeakPolarHBondContact O-CB 3.36Å; S463-Q467 PolarHBondContact O-N 2.67Å
464	F	93	Very high	90.4	Very high	125 Å²	125	103.1 Å²	103.1	55%	0.548	53%	0.526	S	S	.	.	H	α-helix	trans	-64.4	-43.3	176.6	-174.1	-99.7	0	0	0	112.7	K460 L462 Q467 M468	K460-F464 PolarHBondContact O-N 3.41Å; K460-F464 VanDerWaalsContact O-N 3.15Å; L462-F464 VanDerWaalsContact C-N 3.31Å; L462-F464 PolarHBondContact O-N 3.44Å; F464-Q467 PolarHBondContact O-N 3.17Å; F464-M468 HydrophobicContact CE1-CG 4.09Å; F464-M468 HydrophobicContact CE2-CE 4.32Å; F464-M468 HydrophobicContact CZ-CE 3.89Å; F464-M468 HydrophobicContact CZ-CG 4.18Å; F464-M468 PolarHBondContact O-N 3.21Å
465	R	91.1	Very high	90.6	Very high	176 Å²	176	105.2 Å²	105.2	66%	0.664	53%	0.534	S	S	*	.	H	α-helix	trans	-63.4	-42.4	176.4	-76.6	179.7	179.8	-172.6	1.2	112	S461 L462 M468 L469	S461-R465 WeakPolarHBondContact O-CB 3.25Å; S461-R465 WeakPolarHBondContact O-CG 3.18Å; S461-R465 PolarHBondContact O-N 2.93Å; S461-R465 VanDerWaalsContact O-N 3.09Å; L462-R465 PolarHBondContact O-N 3.15Å; L462-R465 VanDerWaalsContact O-N 3.14Å; R465-M468 PolarHBondContact O-N 3.24Å; R465-L469 WeakPolarHBondContact O-CB 3.35Å; R465-L469 WeakPolarHBondContact O-CD1 3.34Å; R465-L469 WeakPolarHBondContact O-CG 3.49Å; R465-L469 PolarHBondContact O-N 3.28Å
466	S	92.6	Very high	90.3	Very high	73 Å²	73	107.7 Å²	107.7	51%	0.51	54%	0.538	S	S	.	.	H	α-helix	trans	-62.5	-41.8	176.3	-67.6	0	0	0	0	111.7	L462 S463 L469 A470	L462-S466 WeakPolarHBondContact O-CB 3.31Å; L462-S466 PolarHBondContact O-N 3.09Å; L462-S466 PolarHBondContact O-OG 2.94Å; S463-S466 PolarHBondContact O-N 3.01Å; S466-L469 PolarHBondContact O-N 3.16Å; S466-A470 WeakPolarHBondContact O-CB 3.28Å; S466-A470 PolarHBondContact O-N 3.07Å
467	Q	91.6	Very high	90	Very high	118 Å²	118	108.4 Å²	108.4	55%	0.551	54%	0.542	S	S	*	.	H	α-helix	trans	-65.9	-41.6	176.4	-168.1	174.2	6.5	0	0	112	S463 F464 A470 M471	S463-Q467 WeakPolarHBondContact O-CB 3.36Å; S463-Q467 PolarHBondContact O-N 2.67Å; F464-Q467 PolarHBondContact O-N 3.17Å; Q467-A470 PolarHBondContact O-N 3.07Å; Q467-M471 PolarHBondContact O-N 3.49Å
468	M	91.8	Very high	89.6	Confident	83 Å²	83	106.9 Å²	106.9	41%	0.409	54%	0.538	S	S	.	.	H	α-helix	trans	-67.1	-38.1	174.7	-83.7	-56.7	171.8	0	0	113.2	F464 R465 M471 N472	F464-M468 HydrophobicContact CE1-CG 4.09Å; F464-M468 HydrophobicContact CE2-CE 4.32Å; F464-M468 HydrophobicContact CZ-CE 3.89Å; F464-M468 HydrophobicContact CZ-CG 4.18Å; F464-M468 PolarHBondContact O-N 3.21Å; R465-M468 PolarHBondContact O-N 3.24Å; M468-M471 PolarHBondContact O-N 2.9Å; M468-M471 HydrophobicContact SD-SD 4.29Å; M468-N472 WeakPolarHBondContact O-CB 2.94Å; M468-N472 VanDerWaalsContact O-CG 3.22Å; M468-N472 PolarHBondContact O-N 3.3Å; M468-N472 PolarHBondContact O-ND2 3.03Å
469	L	91.9	Very high	89	Confident	104 Å²	104	106.5 Å²	106.5	55%	0.545	54%	0.538	S	S	.	.	H	α-helix	trans	-62.3	-44.1	173.5	-82	158.6	0	0	0	111	R465 S466 N472 I473	R465-L469 WeakPolarHBondContact O-CB 3.35Å; R465-L469 WeakPolarHBondContact O-CD1 3.34Å; R465-L469 WeakPolarHBondContact O-CG 3.49Å; R465-L469 PolarHBondContact O-N 3.28Å; S466-L469 PolarHBondContact O-N 3.16Å; L469-N472 PolarHBondContact O-N 3.4Å; L469-I473 WeakPolarHBondContact O-CB 3.2Å; L469-I473 WeakPolarHBondContact O-CG1 3.38Å; L469-I473 PolarHBondContact O-N 2.97Å
470	A	91.7	Very high	87.8	Confident	57 Å²	57	107.2 Å²	107.2	47%	0.471	54%	0.539	S	S	.	.	H	α-helix	trans	-58.9	-48.3	175.5	0	0	0	0	0	111.7	S466 Q467 N472 I473 E474	S466-A470 WeakPolarHBondContact O-CB 3.28Å; S466-A470 PolarHBondContact O-N 3.07Å; Q467-A470 PolarHBondContact O-N 3.07Å; A470-N472 VanDerWaalsContact C-N 3.34Å; A470-N472 PolarHBondContact O-N 3.05Å; A470-I473 PolarHBondContact O-N 3.35Å; A470-E474 WeakPolarHBondContact O-CB 3.15Å; A470-E474 PolarHBondContact O-N 3.46Å
471	M	91.9	Very high	86.3	Confident	90 Å²	90	102.6 Å²	102.6	44%	0.443	53%	0.527	S	S	.	.	H	α-helix	trans	-61	-39.7	175.8	-77.3	-174.5	151.8	0	0	113.1	Q467 M468 E474 K475	Q467-M471 PolarHBondContact O-N 3.49Å; M468-M471 PolarHBondContact O-N 2.9Å; M468-M471 HydrophobicContact SD-SD 4.29Å; M471-E474 PolarHBondContact O-N 3.01Å; M471-K475 WeakPolarHBondContact O-CG 3.47Å; M471-K475 PolarHBondContact O-N 3.14Å
472	N	91.3	Very high	84.8	Confident	93 Å²	93	109.9 Å²	109.9	50%	0.497	55%	0.546	S	S	.	.	H	α-helix	trans	-70.7	-37.7	179.1	-75.2	-22.7	0	0	0	112.1	M468 L469 A470 K475 K476	M468-N472 WeakPolarHBondContact O-CB 2.94Å; M468-N472 VanDerWaalsContact O-CG 3.22Å; M468-N472 PolarHBondContact O-N 3.3Å; M468-N472 PolarHBondContact O-ND2 3.03Å; L469-N472 PolarHBondContact O-N 3.4Å; A470-N472 VanDerWaalsContact C-N 3.34Å; A470-N472 PolarHBondContact O-N 3.05Å; N472-K475 PolarHBondContact O-N 3.19Å; N472-K476 WeakPolarHBondContact O-CB 3.14Å; N472-K476 PolarHBondContact O-N 3.12Å
473	I	90.9	Very high	82.9	Confident	99 Å²	99	109.1 Å²	109.1	51%	0.508	55%	0.55	S	S	.	.	H	α-helix	trans	-64.6	-44.6	174.2	-71.1	166.2	0	0	0	109.9	L469 A470 K475 K476 L477	L469-I473 WeakPolarHBondContact O-CB 3.2Å; L469-I473 WeakPolarHBondContact O-CG1 3.38Å; L469-I473 PolarHBondContact O-N 2.97Å; A470-I473 PolarHBondContact O-N 3.35Å; I473-K475 PolarHBondContact O-N 3.23Å; I473-K476 PolarHBondContact O-N 3.23Å; I473-L477 HydrophobicContact CG2-CD1 3.6Å; I473-L477 HydrophobicContact CG2-CG 4.46Å; I473-L477 WeakPolarHBondContact O-CB 3.36Å; I473-L477 WeakPolarHBondContact O-CG 3.45Å; I473-L477 PolarHBondContact O-N 3.24Å
474	E	89.5	Confident	80.9	Confident	120 Å²	120	113.6 Å²	113.6	56%	0.561	56%	0.562	S	S	*	*	H	α-helix	trans	-60.4	-45.1	176.5	-171.2	-179	-176.3	0	0	112	A470 M471 K476 L477 N478	A470-E474 WeakPolarHBondContact O-CB 3.15Å; A470-E474 PolarHBondContact O-N 3.46Å; M471-E474 PolarHBondContact O-N 3.01Å; E474-K476 PolarHBondContact O-N 3.1Å; E474-L477 PolarHBondContact O-N 2.84Å; E474-N478 WeakPolarHBondContact O-CB 3.48Å; E474-N478 PolarHBondContact O-N 2.91Å
475	K	87.2	Confident	78.8	Confident	139 Å²	139	110.6 Å²	110.6	60%	0.604	56%	0.561	S	S	*	*	H	α-helix	trans	-62.7	-41.5	174.4	-76.3	179.5	-179.6	178.4	0	112.8	M471 N472 I473 N478 Q479	M471-K475 WeakPolarHBondContact O-CG 3.47Å; M471-K475 PolarHBondContact O-N 3.14Å; N472-K475 PolarHBondContact O-N 3.19Å; I473-K475 PolarHBondContact O-N 3.23Å; K475-N478 PolarHBondContact O-N 3.46Å; K475-Q479 PolarHBondContact O-N 3.3Å
476	K	84.6	Confident	76.5	Confident	140 Å²	140	106.1 Å²	106.1	61%	0.609	55%	0.554	S	S	*	*	H	α-helix	trans	-67.3	-41.7	179.1	-172.1	180	179.9	-177	0	111.6	N472 I473 E474 Q479 N480	N472-K476 WeakPolarHBondContact O-CB 3.14Å; N472-K476 PolarHBondContact O-N 3.12Å; I473-K476 PolarHBondContact O-N 3.23Å; E474-K476 PolarHBondContact O-N 3.1Å; K476-Q479 PolarHBondContact O-N 3.04Å; K476-N480 PolarHBondContact O-N 2.92Å
477	L	82.9	Confident	74.3	Confident	109 Å²	109	110.4 Å²	110.4	57%	0.571	57%	0.572	S	S	*	*	H	α-helix	trans	-62.6	-43.1	174.1	-80.6	158.2	0	0	0	111.2	I473 E474 Q479 N480 S481	I473-L477 HydrophobicContact CG2-CD1 3.6Å; I473-L477 HydrophobicContact CG2-CG 4.46Å; I473-L477 WeakPolarHBondContact O-CB 3.36Å; I473-L477 WeakPolarHBondContact O-CG 3.45Å; I473-L477 PolarHBondContact O-N 3.24Å; E474-L477 PolarHBondContact O-N 2.84Å; L477-Q479 VanDerWaalsContact C-N 3.33Å; L477-Q479 PolarHBondContact O-N 2.94Å; L477-N480 PolarHBondContact O-N 2.79Å; L477-S481 PolarHBondContact O-N 2.94Å; L477-S481 PolarHBondContact O-OG 3.21Å
478	N	78.3	Confident	72.3	Confident	96 Å²	96	114.5 Å²	114.5	51%	0.513	58%	0.582	S	S	.	*	H	α-helix	trans	-68.8	-27	176.1	-80.1	-14.7	0	0	0	114	E474 K475 S481 R482	E474-N478 WeakPolarHBondContact O-CB 3.48Å; E474-N478 PolarHBondContact O-N 2.91Å; K475-N478 PolarHBondContact O-N 3.46Å; N478-S481 VanDerWaalsContact CA-OG 3.32Å; N478-S481 WeakPolarHBondContact CA-OG 3.42Å; N478-S481 PolarHBondContact O-OG 3.39Å; N478-S481 VanDerWaalsContact O-OG 3.09Å; N478-R482 WeakPolarHBondContact O-CG 3.19Å; N478-R482 PolarHBondContact O-N 2.75Å
479	Q	72.4	Confident	70.2	Confident	135 Å²	135	114.1 Å²	114.1	63%	0.631	59%	0.592	S	S	*	*	H	α-helix	trans	-73.5	-43.2	170.5	-85.5	-179.1	-17.9	0	0	111.5	K475 K476 L477 S481 R482 S483	K475-Q479 PolarHBondContact O-N 3.3Å; K476-Q479 PolarHBondContact O-N 3.04Å; L477-Q479 VanDerWaalsContact C-N 3.33Å; L477-Q479 PolarHBondContact O-N 2.94Å; Q479-S481 PolarHBondContact O-N 3.45Å; Q479-R482 PolarHBondContact O-N 3.05Å; Q479-S483 WeakPolarHBondContact O-CB 3.48Å; Q479-S483 PolarHBondContact O-N 3.44Å; Q479-S483 PolarHBondContact O-OG 3.4Å
480	N	66.1	Low	67.9	Low	92 Å²	92	115.1 Å²	115.1	49%	0.492	60%	0.603	S	S	.	*	H	α-helix	trans	-63.5	-40.6	176.8	-88.5	14.6	0	0	0	111.8	K476 L477 R482 S483 E484	K476-N480 PolarHBondContact O-N 2.92Å; L477-N480 PolarHBondContact O-N 2.79Å; N480-R482 VanDerWaalsContact C-N 3.3Å; N480-R482 PolarHBondContact O-N 3.38Å; N480-S483 WeakPolarHBondContact O-CA 3.29Å; N480-S483 WeakPolarHBondContact O-CB 3.3Å; N480-S483 PolarHBondContact O-N 3.27Å; N480-E484 PolarHBondContact O-N 3.39Å
481	S	59.9	Low	65.7	Low	64 Å²	64	120.6 Å²	120.6	45%	0.448	62%	0.619	S	S	.	*	H	α-helix	trans	-66.8	-28.9	175.5	58.3	0	0	0	0	113.3	L477 N478 Q479	L477-S481 PolarHBondContact O-N 2.94Å; L477-S481 PolarHBondContact O-OG 3.21Å; N478-S481 VanDerWaalsContact CA-OG 3.32Å; N478-S481 WeakPolarHBondContact CA-OG 3.42Å; N478-S481 PolarHBondContact O-OG 3.39Å; N478-S481 VanDerWaalsContact O-OG 3.09Å; Q479-S481 PolarHBondContact O-N 3.45Å
482	R	57.1	Low	63.3	Low	213 Å²	213	123.8 Å²	123.8	80%	0.804	64%	0.638	S	S	*	*	H	α-helix	trans	-75	-24.3	168.2	-80.3	-176.1	169.2	-174.4	-2.8	113.8	N478 Q479 N480	N478-R482 WeakPolarHBondContact O-CG 3.19Å; N478-R482 PolarHBondContact O-N 2.75Å; Q479-R482 PolarHBondContact O-N 3.05Å; N480-R482 VanDerWaalsContact C-N 3.3Å; N480-R482 PolarHBondContact O-N 3.38Å
483	S	54	Low	60.7	Low	93 Å²	93	125.2 Å²	125.2	65%	0.65	65%	0.654	S	S	*	*	H	α-helix	trans	-83.9	-25.9	179.3	-50.5	0	0	0	0	112.4	Q479 N480	Q479-S483 WeakPolarHBondContact O-CB 3.48Å; Q479-S483 PolarHBondContact O-N 3.44Å; Q479-S483 PolarHBondContact O-OG 3.4Å; N480-S483 WeakPolarHBondContact O-CA 3.29Å; N480-S483 WeakPolarHBondContact O-CB 3.3Å; N480-S483 PolarHBondContact O-N 3.27Å
484	E	49.5	Very low	58.3	Low	167 Å²	167	123.4 Å²	123.4	78%	0.78	66%	0.661	S	S	*	*	S	Bend	trans	-82.6	-9.7	173.8	-77.4	-176.7	160	0	0	113.6	N480 P486	N480-E484 PolarHBondContact O-N 3.39Å; E484-P486 VanDerWaalsContact O-CD 3.28Å; E484-P486 WeakPolarHBondContact O-CD 3.39Å
485	A	49.6	Very low	55.9	Low	62 Å²	62	127 Å²	127	51%	0.512	68%	0.675	S	S	.	*	S	Bend	trans	-77.7	111.2	168.3	0	0	0	0	0	108.8
486	P	42.8	Very low	53.4	Low	82 Å²	82	134.3 Å²	134.3	53%	0.532	70%	0.701	S	S	.	*			trans	-73	139.2	-177.3	-0.5	17	0	0	0	109.4	E484 W488	E484-P486 VanDerWaalsContact O-CD 3.28Å; E484-P486 WeakPolarHBondContact O-CD 3.39Å; P486-W488 PolarHBondContact O-N 3Å
487	N	45.1	Very low	51.9	Low	163 Å²	163	134.1 Å²	134.1	87%	0.872	71%	0.705	S	S	*	*	T	Hydrogen-bonded Turn	trans	-62.9	20	-171.8	-124.9	11.4	0	0	0	116.1
488	W	50.4	Low	50.3	Low	203 Å²	203	135.4 Å²	135.4	77%	0.769	71%	0.712	S	S	*	*	T	Hydrogen-bonded Turn	trans	-99.6	-10.1	178.3	66	-99.8	0	0	0	114.1	P486 T490	P486-W488 PolarHBondContact O-N 3Å; W488-T490 VanDerWaalsContact C-N 3.34Å; W488-T490 PolarHBondContact O-N 2.82Å
489	A	47.3	Very low	48.7	Very low	75 Å²	75	137.6 Å²	137.6	62%	0.62	72%	0.723	S	S	*	*	S	Bend	trans	-86.6	10	-173.8	0	0	0	0	0	115.4
490	T	44	Very low	47.3	Very low	125 Å²	125	137.7 Å²	137.7	77%	0.767	73%	0.729	S	S	*	*	S	Bend	trans	-120.2	41	178.2	52.1	0	0	0	0	113.1	W488	W488-T490 VanDerWaalsContact C-N 3.34Å; W488-T490 PolarHBondContact O-N 2.82Å
491	Q	45.4	Very low	46.1	Very low	173 Å²	173	140.6 Å²	140.6	81%	0.808	74%	0.744	S	S	*	*	S	Bend	trans	-123.6	137	151.6	-84.4	-178.7	-11.6	0	0	107.9
492	D	41.2	Very low	45.2	Very low	157 Å²	157	145.7 Å²	145.7	84%	0.84	76%	0.763	S	S	*	*			trans	81.1	86.4	177.6	-60.5	-18.6	0	0	0	118.1
493	S	37.4	Very low	44.4	Very low	122 Å²	122	140.9 Å²	140.9	85%	0.853	76%	0.761	S	S	*	*				-173.5	81.3	119.2	28.3	0	0	0	0	110.8
494	G	39.9	Very low	43.6	Very low	62 Å²	62	144.5 Å²	144.5	64%	0.639	77%	0.769	S	S	*	*			trans	-80	160.6	141.1	0	0	0	0	0	109.1
495	F	38	Very low	43.1	Very low	195 Å²	195	142.7 Å²	142.7	86%	0.855	77%	0.768	S	S	*	*			trans	76.3	113.3	-169.9	-57.4	-83.8	0	0	0	112.1
496	Y	36.5	Very low	42.5	Very low	293 Å²	293	150 Å²	150	100%	1.149	79%	0.791	S	S	*	*			cis	-149.5	0	28	-116.8	-90.2	0	0	0	110.5

Retrieved 496 of 496 residues in 233.1 ms (Link to these results)

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