A0A3B3TNP4_9TELE Loading...

Caspase 2, apoptosis-related cysteine peptidase

AlphaFold DB , UniProt , Accession A0A3B3TNP4, Species 9TELE (Poecilia latipinna, sailfin molly), Gene n/a, Length 460 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M39.5Very low68.2Low241 Ų241100.2 Ų100.2100%1.18750%0.501SS*.  0140.30-75169.2-97.900107.1
2L42.7Very low69.4Low173 Ų173103.8 Ų103.891%0.90651%0.511SS*.  trans-74.4134.8170.1-70.9160.7000108C4L2-C4 PolarHBondContact O-N 2.75Å
3E48.5Very low70.4Confident156 Ų15696.7 Ų96.773%0.72948%0.479SS*.  trans-71.4112.6176.5-66-165140.400109.5G5E3-G5 PolarHBondContact O-N 3.42Å
4C55.7Low71.6Confident136 Ų13690.2 Ų90.292%0.91945%0.447SS*.  trans-88109.3179.4-170.40000110.2L2L2-C4 PolarHBondContact O-N 2.75Å
5G65.1Low72.5Confident8 Ų894.4 Ų94.48%0.08246%0.456CS..SBendtrans116.7-172.8179.200000113.5E3 G70E3-G5 PolarHBondContact O-N 3.42Å; G5-G70 CarbonylContact C-O 3.57Å; G5-G70 CarbonylContact O-C 3.13Å
6M86.1Confident73.2Confident3 Ų3100 Ų1002%0.01547%0.471CS..SBendtrans-69.5147.3179.2-179.4-175.7-70.500111.6D10 K11 L14 L66 P67 G70 A73 F74M6-D10 HydrophobicContact CG-CB 3.95Å; M6-D10 HydrophobicContact SD-CB 4.18Å; M6-K11 HydrophobicContact CB-CG 3.98Å; M6-K11 HydrophobicContact CG-CG 4.09Å; M6-K11 WeakPolarHBondContact O-CE 3.25Å; M6-K11 PolarHBondContact O-NZ 2.79Å; M6-K11 HydrophobicContact SD-CG 4.16Å; M6-L14 HydrophobicContact CE-CD1 3.72Å; M6-L14 HydrophobicContact SD-CD1 3.68Å; M6-L66 HydrophobicContact CE-CB 4.14Å; M6-P67 PolarHBondContact N-O 3.29Å; M6-P67 VanDerWaalsContact N-O 3.11Å; M6-G70 VanDerWaalsContact CA-O 3.26Å; M6-G70 WeakPolarHBondContact CA-O 3.19Å; M6-G70 PolarHBondContact N-O 3.41Å; M6-A73 HydrophobicContact CE-CB 4.05Å; M6-F74 HydrophobicContact CE-CB 3.89Å; M6-F74 HydrophobicContact CG-CB 4.07Å; M6-F74 HydrophobicContact SD-CB 4.04Å; M6-F74 HydrophobicContact SD-CD2 4.19Å
7L82.8Confident73.9Confident57 Ų5795.1 Ų95.130%0.29845%0.448SS..  trans-57.9140.7176.5-64.1171.8000111.6R9 D10 K11L7-R9 VanDerWaalsContact C-N 3.29Å; L7-R9 HydrophobicContact CB-CG 4.41Å; L7-R9 PolarHBondContact O-N 3.1Å; L7-D10 HydrophobicContact CB-CB 4.45Å; L7-D10 WeakPolarHBondContact CB-OD2 3.41Å; L7-D10 WeakPolarHBondContact O-CB 3.2Å; L7-D10 PolarHBondContact O-N 2.81Å; L7-K11 PolarHBondContact O-N 3.18Å
8E78.6Confident74.6Confident102 Ų10292.5 Ų92.548%0.47744%0.442SS..Hα-helixtrans-67.1-27.8-170.3-162.160.3-149.100113.7D10 K11 K12 R15E8-D10 PolarHBondContact O-N 3.48Å; E8-K11 VanDerWaalsContact OE2-CD 3.3Å; E8-K11 WeakPolarHBondContact OE2-CD 3.41Å; E8-K11 WeakPolarHBondContact OE2-CE 3.44Å; E8-K11 IonicContact OE2-NZ 3.93Å; E8-K11 PolarHBondContact OE2-NZ 2.85Å; E8-K12 VanDerWaalsContact O-CB 3.28Å; E8-K12 WeakPolarHBondContact O-CB 3.27Å; E8-K12 PolarHBondContact O-N 3.23Å; E8-R15 IonicContact OE1-CZ 2.75Å; E8-R15 IonicContact OE1-NH1 3.23Å; E8-R15 PolarHBondContact OE1-NH1 3.36Å; E8-R15 IonicContact OE1-NH2 3.23Å
9R81.5Confident74.9Confident174 Ų17491.2 Ų91.266%0.65745%0.448SS*.Hα-helixtrans-59.6-38.7171.178.6-175.1-175.1-174.7-4.5111.4L7 K12 A13L7-R9 VanDerWaalsContact C-N 3.29Å; L7-R9 HydrophobicContact CB-CG 4.41Å; L7-R9 PolarHBondContact O-N 3.1Å; R9-K12 WeakPolarHBondContact O-CB 3.41Å; R9-K12 PolarHBondContact O-N 2.9Å; R9-A13 PolarHBondContact O-N 3.42Å
10D85.1Confident75.5Confident15 Ų1589.2 Ų89.28%0.0844%0.441CS..Hα-helixtrans-84.1-37.8-173.1-64.4-34.2000109.6M6 L7 E8 K12 A13 L14 F74M6-D10 HydrophobicContact CG-CB 3.95Å; M6-D10 HydrophobicContact SD-CB 4.18Å; L7-D10 HydrophobicContact CB-CB 4.45Å; L7-D10 WeakPolarHBondContact CB-OD2 3.41Å; L7-D10 WeakPolarHBondContact O-CB 3.2Å; L7-D10 PolarHBondContact O-N 2.81Å; E8-D10 PolarHBondContact O-N 3.48Å; D10-K12 VanDerWaalsContact C-N 3.26Å; D10-K12 PolarHBondContact O-N 2.88Å; D10-A13 PolarHBondContact O-N 3.17Å; D10-L14 PolarHBondContact O-N 3.07Å; D10-F74 HydrophobicContact CB-CB 3.96Å; D10-F74 HydrophobicContact CB-CD1 3.79Å; D10-F74 HydrophobicContact CB-CD2 3.69Å; D10-F74 HydrophobicContact CB-CE1 4.09Å; D10-F74 HydrophobicContact CB-CE2 3.99Å; D10-F74 HydrophobicContact CB-CG 3.55Å; D10-F74 HydrophobicContact CB-CZ 4.16Å; D10-F74 VanDerWaalsContact CG-CD1 3.49Å; D10-F74 VanDerWaalsContact OD1-CE1 3.3Å; D10-F74 WeakPolarHBondContact OD1-CE1 3.46Å
11K84.7Confident76.1Confident37 Ų3785 Ų8516%0.16142%0.42CS..Hα-helixtrans-55.2-41.4163.7-59.7-157.3-161.778.40111.7M6 L7 E8 R15 P67M6-K11 HydrophobicContact CB-CG 3.98Å; M6-K11 HydrophobicContact CG-CG 4.09Å; M6-K11 WeakPolarHBondContact O-CE 3.25Å; M6-K11 PolarHBondContact O-NZ 2.79Å; M6-K11 HydrophobicContact SD-CG 4.16Å; L7-K11 PolarHBondContact O-N 3.18Å; E8-K11 VanDerWaalsContact OE2-CD 3.3Å; E8-K11 WeakPolarHBondContact OE2-CD 3.41Å; E8-K11 WeakPolarHBondContact OE2-CE 3.44Å; E8-K11 IonicContact OE2-NZ 3.93Å; E8-K11 PolarHBondContact OE2-NZ 2.85Å; K11-R15 WeakPolarHBondContact O-CB 3.3Å; K11-R15 VanDerWaalsContact O-CG 3.3Å; K11-R15 WeakPolarHBondContact O-CG 3.36Å; K11-R15 PolarHBondContact O-N 3.14Å; K11-P67 HydrophobicContact CD-CB 4.07Å; K11-P67 HydrophobicContact CG-CB 4.22Å
12K82.4Confident78.3Confident144 Ų14474.7 Ų74.763%0.62637%0.372SS*.Hα-helixtrans-68-38.1179.5-172.1-179.5-179.8-175.20111.9E8 R9 D10 R16E8-K12 VanDerWaalsContact O-CB 3.28Å; E8-K12 WeakPolarHBondContact O-CB 3.27Å; E8-K12 PolarHBondContact O-N 3.23Å; R9-K12 WeakPolarHBondContact O-CB 3.41Å; R9-K12 PolarHBondContact O-N 2.9Å; D10-K12 VanDerWaalsContact C-N 3.26Å; D10-K12 PolarHBondContact O-N 2.88Å; K12-R16 VanDerWaalsContact O-CB 3.3Å; K12-R16 WeakPolarHBondContact O-CB 3.49Å; K12-R16 PolarHBondContact O-N 3.33Å
13A82.9Confident80.2Confident11 Ų1174.1 Ų74.19%0.09136%0.362CS..Hα-helixtrans-62.8-49.2173.300000111.9R9 D10 R15 R16 N17 F74 I93R9-A13 PolarHBondContact O-N 3.42Å; D10-A13 PolarHBondContact O-N 3.17Å; A13-R15 PolarHBondContact O-N 3.26Å; A13-R16 PolarHBondContact O-N 3.41Å; A13-N17 PolarHBondContact O-N 2.89Å; A13-N17 VanDerWaalsContact O-N 3.12Å; A13-F74 HydrophobicContact CB-CE2 4.37Å; A13-F74 HydrophobicContact CB-CZ 4.39Å; A13-I93 HydrophobicContact CB-CG2 4.25Å
14L86.9Confident82Confident6 Ų671.6 Ų71.63%0.03135%0.35CS..Hα-helixtrans-61.4-44.3175.9-68.3-176.1000112.5M6 D10 R16 N17 S18 L21 L63 F74 F77 I93M6-L14 HydrophobicContact CE-CD1 3.72Å; M6-L14 HydrophobicContact SD-CD1 3.68Å; D10-L14 PolarHBondContact O-N 3.07Å; L14-R16 PolarHBondContact O-N 3.33Å; L14-N17 PolarHBondContact O-N 2.91Å; L14-S18 WeakPolarHBondContact O-CA 3.44Å; L14-S18 WeakPolarHBondContact O-CB 3.49Å; L14-S18 PolarHBondContact O-N 3.45Å; L14-L21 HydrophobicContact CD2-CD1 4.12Å; L14-L63 HydrophobicContact CD2-CD2 4.34Å; L14-F74 HydrophobicContact CD1-CD2 4.32Å; L14-F74 HydrophobicContact CD2-CD2 4.4Å; L14-F74 HydrophobicContact CD2-CE2 4.2Å; L14-F74 HydrophobicContact CG-CD2 4.14Å; L14-F74 HydrophobicContact CG-CE2 4.12Å; L14-F77 HydrophobicContact CD2-CD1 4.12Å; L14-F77 HydrophobicContact CD2-CE1 3.85Å; L14-I93 HydrophobicContact CD2-CD1 3.99Å
15R84.7Confident83.7Confident153 Ų15365.4 Ų65.458%0.57731%0.308SS*.Hα-helixtrans-59.7-45.9175.5-76.4177.9-174.3139.30.7111.9E8 K11 A13 N17 S18E8-R15 IonicContact OE1-CZ 2.75Å; E8-R15 IonicContact OE1-NH1 3.23Å; E8-R15 PolarHBondContact OE1-NH1 3.36Å; E8-R15 IonicContact OE1-NH2 3.23Å; K11-R15 WeakPolarHBondContact O-CB 3.3Å; K11-R15 VanDerWaalsContact O-CG 3.3Å; K11-R15 WeakPolarHBondContact O-CG 3.36Å; K11-R15 PolarHBondContact O-N 3.14Å; A13-R15 PolarHBondContact O-N 3.26Å; R15-N17 VanDerWaalsContact C-N 3.34Å; R15-N17 PolarHBondContact O-N 3.01Å; R15-S18 WeakPolarHBondContact O-CB 3.45Å; R15-S18 PolarHBondContact O-N 3.43Å; R15-S18 PolarHBondContact O-OG 2.9Å
16R83.3Confident84.8Confident184 Ų18469 Ų6969%0.69433%0.328SS*.Hα-helixtrans-60.4-41.6-179.1-175.1179.8-171.8170.33.6112.4K12 A13 L14K12-R16 VanDerWaalsContact O-CB 3.3Å; K12-R16 WeakPolarHBondContact O-CB 3.49Å; K12-R16 PolarHBondContact O-N 3.33Å; A13-R16 PolarHBondContact O-N 3.41Å; L14-R16 PolarHBondContact O-N 3.33Å
17N85.4Confident85Confident17 Ų1769.1 Ų69.19%0.09133%0.329CS..Hα-helixtrans-94.5-0.9-176.7-65.8-23.6000113.6A13 L14 R15 A19 V20 L21 L92 I93A13-N17 PolarHBondContact O-N 2.89Å; A13-N17 VanDerWaalsContact O-N 3.12Å; L14-N17 PolarHBondContact O-N 2.91Å; R15-N17 VanDerWaalsContact C-N 3.34Å; R15-N17 PolarHBondContact O-N 3.01Å; N17-A19 VanDerWaalsContact C-N 3.29Å; N17-A19 PolarHBondContact O-N 2.84Å; N17-A19 VanDerWaalsContact O-N 3.15Å; N17-V20 WeakPolarHBondContact O-CB 3.46Å; N17-V20 PolarHBondContact O-N 2.99Å; N17-L21 HydrophobicContact CB-CD1 3.94Å; N17-L21 HydrophobicContact CB-CG 4.23Å; N17-L21 WeakPolarHBondContact O-CG 3.38Å; N17-L21 PolarHBondContact O-N 3.01Å; N17-L92 HydrophobicContact CB-CD2 4.35Å; N17-L92 HydrophobicContact CB-CG 4.47Å; N17-L92 PolarHBondContact ND2-O 3.4Å; N17-I93 WeakPolarHBondContact ND2-CA 3.34Å
18S86.3Confident85.1Confident48 Ų4868.9 Ų68.934%0.33633%0.328SS..Hα-helixtrans-51.3-40.3-174.659.50000114.3L14 R15 V20 L21 C22L14-S18 WeakPolarHBondContact O-CA 3.44Å; L14-S18 WeakPolarHBondContact O-CB 3.49Å; L14-S18 PolarHBondContact O-N 3.45Å; R15-S18 WeakPolarHBondContact O-CB 3.45Å; R15-S18 PolarHBondContact O-N 3.43Å; R15-S18 PolarHBondContact O-OG 2.9Å; S18-V20 VanDerWaalsContact C-N 3.25Å; S18-V20 PolarHBondContact O-N 3.24Å; S18-L21 PolarHBondContact O-N 3.46Å; S18-C22 VanDerWaalsContact O-CB 3.32Å; S18-C22 WeakPolarHBondContact O-CB 3.3Å; S18-C22 PolarHBondContact O-N 3.15Å; S18-C22 PolarHBondContact O-SG 3.37Å
19A81.7Confident85.5Confident67 Ų6769.9 Ų69.955%0.55433%0.333SS*.Hα-helixtrans-67.8-22179.100000114.1N17 K23N17-A19 VanDerWaalsContact C-N 3.29Å; N17-A19 PolarHBondContact O-N 2.84Å; N17-A19 VanDerWaalsContact O-N 3.15Å; A19-K23 WeakPolarHBondContact O-CD 3.25Å; A19-K23 WeakPolarHBondContact O-CG 3.43Å
20V86Confident85.9Confident52 Ų5266.5 Ų66.532%0.31533%0.327SS..Hα-helixtrans-88.4-47.3172.7-174.90000109.5N17 S18 C22 K23 Q24 L92N17-V20 WeakPolarHBondContact O-CB 3.46Å; N17-V20 PolarHBondContact O-N 2.99Å; S18-V20 VanDerWaalsContact C-N 3.25Å; S18-V20 PolarHBondContact O-N 3.24Å; V20-C22 PolarHBondContact O-N 3.11Å; V20-K23 PolarHBondContact O-N 3.39Å; V20-Q24 HydrophobicContact CG1-CG 4.3Å; V20-Q24 PolarHBondContact O-N 3.46Å; V20-L92 HydrophobicContact CB-CD2 3.87Å; V20-L92 HydrophobicContact CG1-CD2 3.6Å; V20-L92 HydrophobicContact CG2-CD2 4.29Å
21L87.8Confident86.2Confident0 Ų065.8 Ų65.80%032%0.324CS..Hα-helixtrans-58.1-47.9179.1-63.2167.1000111.4L14 N17 S18 K23 Q24 L25 L63 L89 I93L14-L21 HydrophobicContact CD2-CD1 4.12Å; N17-L21 HydrophobicContact CB-CD1 3.94Å; N17-L21 HydrophobicContact CB-CG 4.23Å; N17-L21 WeakPolarHBondContact O-CG 3.38Å; N17-L21 PolarHBondContact O-N 3.01Å; S18-L21 PolarHBondContact O-N 3.46Å; L21-K23 PolarHBondContact O-N 3.08Å; L21-Q24 PolarHBondContact O-N 2.92Å; L21-L25 WeakPolarHBondContact O-CB 3.49Å; L21-L25 PolarHBondContact O-N 2.89Å; L21-L63 HydrophobicContact CB-CD1 3.65Å; L21-L63 HydrophobicContact CB-CD2 4.36Å; L21-L63 HydrophobicContact CD1-CD2 4.02Å; L21-L89 HydrophobicContact CD2-CB 3.97Å; L21-L89 HydrophobicContact CD2-CD1 4.18Å; L21-L89 HydrophobicContact CD2-CD2 4.14Å; L21-L89 HydrophobicContact CD2-CG 4.32Å; L21-I93 HydrophobicContact CD1-CD1 4Å; L21-I93 HydrophobicContact CD1-CG1 4.29Å; L21-I93 HydrophobicContact CD2-CD1 3.88Å; L21-I93 HydrophobicContact CD2-CG1 4.4Å
22C86.6Confident86.5Confident25 Ų2564.2 Ų64.217%0.16932%0.317CS..Hα-helixtrans-60.6-11.1175.5-69.90000115.1S18 V20S18-C22 VanDerWaalsContact O-CB 3.32Å; S18-C22 WeakPolarHBondContact O-CB 3.3Å; S18-C22 PolarHBondContact O-N 3.15Å; S18-C22 PolarHBondContact O-SG 3.37Å; V20-C22 PolarHBondContact O-N 3.11Å
23K81.6Confident86.9Confident162 Ų16261.8 Ų61.870%0.70431%0.308SS*.Hα-helixtrans-110.2-29.5179.6-67.3-178.5-177.5178.10114A19 V20 L21A19-K23 WeakPolarHBondContact O-CD 3.25Å; A19-K23 WeakPolarHBondContact O-CG 3.43Å; V20-K23 PolarHBondContact O-N 3.39Å; L21-K23 PolarHBondContact O-N 3.08Å
24Q86.8Confident87.2Confident103 Ų10362.6 Ų62.648%0.48131%0.312SS..Hα-helixtrans-114.8-17.7-172.4-67.6-177.1-17.700113.6V20 L21 V26 L89V20-Q24 HydrophobicContact CG1-CG 4.3Å; V20-Q24 PolarHBondContact O-N 3.46Å; L21-Q24 PolarHBondContact O-N 2.92Å; Q24-V26 PolarHBondContact O-N 2.95Å; Q24-L89 HydrophobicContact CB-CD2 3.9Å
25L90.9Very high87.4Confident5 Ų562.3 Ų62.33%0.02631%0.311CS..  trans-66.6125.8173.6-17466.8000109.8L21 V27 L31 S59 L62 L63 F77 L81 L89L21-L25 WeakPolarHBondContact O-CB 3.49Å; L21-L25 PolarHBondContact O-N 2.89Å; L25-V27 HydrophobicContact CD2-CG2 3.78Å; L25-V27 HydrophobicContact CG-CG2 3.89Å; L25-L31 HydrophobicContact CD1-CD2 4.2Å; L25-S59 PolarHBondContact O-OG 3.02Å; L25-L62 HydrophobicContact CD2-CD2 4.27Å; L25-L63 HydrophobicContact CD2-CG 4.48Å; L25-F77 HydrophobicContact CD1-CE2 4.26Å; L25-F77 HydrophobicContact CD1-CZ 4.12Å; L25-F77 HydrophobicContact CD2-CE2 4.35Å; L25-F77 HydrophobicContact CD2-CZ 4.16Å; L25-L81 HydrophobicContact CD1-CD2 3.53Å; L25-L89 HydrophobicContact CB-CD1 4.04Å; L25-L89 HydrophobicContact CD1-CD1 3.83Å
26V89.3Confident87.6Confident84 Ų8458.1 Ų58.151%0.50930%0.298SS..  trans-95.1105.4166.4-177.90000106.5Q24 D28 Q86Q24-V26 PolarHBondContact O-N 2.95Å; V26-D28 HydrophobicContact CG1-CB 4.23Å; V26-D28 PolarHBondContact O-N 3.03Å; V26-Q86 PolarHBondContact O-NE2 3.48Å
27V88.9Confident87.9Confident6 Ų653.5 Ų53.54%0.03630%0.299CS..  trans-88.995.5167.5-177.50000107.4L25 L31 I32 I49 R58 L62L25-V27 HydrophobicContact CD2-CG2 3.78Å; L25-V27 HydrophobicContact CG-CG2 3.89Å; V27-L31 HydrophobicContact CB-CD2 4.41Å; V27-L31 HydrophobicContact CG1-CD2 4.45Å; V27-L31 HydrophobicContact CG2-CD2 4.1Å; V27-I32 HydrophobicContact CG1-CD1 3.71Å; V27-I32 HydrophobicContact CG1-CG1 3.7Å; V27-I49 HydrophobicContact CG1-CG2 3.81Å; V27-R58 HydrophobicContact CB-CB 3.88Å; V27-R58 HydrophobicContact CG1-CB 4.19Å; V27-R58 HydrophobicContact CG2-CB 4.36Å; V27-L62 HydrophobicContact CG1-CD2 4.27Å; V27-L62 HydrophobicContact CG2-CB 4.4Å; V27-L62 HydrophobicContact CG2-CD2 3.74Å
28D86.1Confident88Confident52 Ų5257.2 Ų57.228%0.27832%0.319SS..  trans-103.9-177.9173.469.1-5000111.2V26 L30 L31 I32V26-D28 HydrophobicContact CG1-CB 4.23Å; V26-D28 PolarHBondContact O-N 3.03Å; D28-L30 VanDerWaalsContact C-N 3.32Å; D28-L30 PolarHBondContact OD1-N 2.9Å; D28-L31 VanDerWaalsContact OD1-CB 3.31Å; D28-L31 WeakPolarHBondContact OD1-CB 3.47Å; D28-L31 PolarHBondContact OD1-N 3.18Å; D28-I32 WeakPolarHBondContact O-CG1 3.39Å; D28-I32 PolarHBondContact O-N 2.95Å
29E87.6Confident88Confident123 Ų12357.8 Ų57.858%0.57533%0.333SS*.Hα-helixtrans-67.7-33.6-178.9-154.2-176.8145.400112I32 Q33 M50E29-I32 PolarHBondContact O-N 3.4Å; E29-Q33 WeakPolarHBondContact O-CB 3.2Å; E29-Q33 VanDerWaalsContact O-CG 3.24Å; E29-Q33 WeakPolarHBondContact O-CG 3.5Å; E29-Q33 PolarHBondContact O-N 3.04Å; E29-Q33 PolarHBondContact OE1-NE2 3.24Å; E29-M50 HydrophobicContact CB-CE 4.25Å
30L88.1Confident88.4Confident103 Ų10355.2 Ų55.254%0.53931%0.31SS..Hα-helixtrans-67.7-46.7179.8-64.8173.3000111.7D28 I32 Q33 S34 T84D28-L30 VanDerWaalsContact C-N 3.32Å; D28-L30 PolarHBondContact OD1-N 2.9Å; L30-I32 PolarHBondContact O-N 2.96Å; L30-Q33 PolarHBondContact O-N 3.35Å; L30-S34 PolarHBondContact O-N 2.93Å; L30-S34 PolarHBondContact O-OG 3.17Å; L30-T84 HydrophobicContact CB-CG2 4.01Å
31L91.4Very high88.5Confident0 Ų053.1 Ų53.10%030%0.296CS..Hα-helixtrans-57-40.3175.7-168.478.6000111.3L25 V27 D28 L35 L62 A80 T84L25-L31 HydrophobicContact CD1-CD2 4.2Å; V27-L31 HydrophobicContact CB-CD2 4.41Å; V27-L31 HydrophobicContact CG1-CD2 4.45Å; V27-L31 HydrophobicContact CG2-CD2 4.1Å; D28-L31 VanDerWaalsContact OD1-CB 3.31Å; D28-L31 WeakPolarHBondContact OD1-CB 3.47Å; D28-L31 PolarHBondContact OD1-N 3.18Å; L31-L35 VanDerWaalsContact O-CG 3.27Å; L31-L35 WeakPolarHBondContact O-CG 3.42Å; L31-L35 PolarHBondContact O-N 2.93Å; L31-L62 HydrophobicContact CD2-CD2 3.74Å; L31-A80 HydrophobicContact CD1-CB 3.72Å; L31-T84 HydrophobicContact CB-CG2 3.96Å; L31-T84 HydrophobicContact CD1-CG2 4.08Å
32I91.8Very high88.7Confident4 Ų456.5 Ų56.52%0.02132%0.317CS..Hα-helixtrans-73.8-41.8-179.1-68.2-66.1000111.2V27 D28 E29 L30 L35 Q36 L41 A46 I49 M50 L62V27-I32 HydrophobicContact CG1-CD1 3.71Å; V27-I32 HydrophobicContact CG1-CG1 3.7Å; D28-I32 WeakPolarHBondContact O-CG1 3.39Å; D28-I32 PolarHBondContact O-N 2.95Å; E29-I32 PolarHBondContact O-N 3.4Å; L30-I32 PolarHBondContact O-N 2.96Å; I32-L35 PolarHBondContact O-N 3.21Å; I32-Q36 WeakPolarHBondContact O-CG 3.28Å; I32-Q36 PolarHBondContact O-N 2.7Å; I32-L41 HydrophobicContact CD1-CD1 3.65Å; I32-A46 HydrophobicContact CG2-CB 3.37Å; I32-I49 HydrophobicContact CD1-CB 4.44Å; I32-I49 HydrophobicContact CD1-CD1 4Å; I32-I49 HydrophobicContact CD1-CG2 4.01Å; I32-M50 HydrophobicContact CG1-SD 4.17Å; I32-L62 HydrophobicContact CD1-CD1 4.5Å
33Q90.2Very high88.7Confident93 Ų9362.1 Ų62.144%0.43534%0.341SS..Hα-helixtrans-61.5-44.2174.7-75.4176.214.800112.2E29 L30 L35 Q36 A37E29-Q33 WeakPolarHBondContact O-CB 3.2Å; E29-Q33 VanDerWaalsContact O-CG 3.24Å; E29-Q33 WeakPolarHBondContact O-CG 3.5Å; E29-Q33 PolarHBondContact O-N 3.04Å; E29-Q33 PolarHBondContact OE1-NE2 3.24Å; L30-Q33 PolarHBondContact O-N 3.35Å; Q33-L35 VanDerWaalsContact C-N 3.35Å; Q33-L35 PolarHBondContact O-N 3.32Å; Q33-Q36 PolarHBondContact O-N 3.49Å; Q33-Q36 VanDerWaalsContact O-N 3.17Å; Q33-A37 PolarHBondContact O-N 3.12Å
34S89.1Confident88.9Confident27 Ų2759.4 Ų59.419%0.18933%0.334CS..Hα-helixtrans-59.1-44.5174.3-67.50000111.8L30 Q36 A37 D38 E83L30-S34 PolarHBondContact O-N 2.93Å; L30-S34 PolarHBondContact O-OG 3.17Å; S34-Q36 VanDerWaalsContact C-N 3.3Å; S34-Q36 PolarHBondContact O-N 2.93Å; S34-A37 PolarHBondContact O-N 3.31Å; S34-D38 PolarHBondContact O-N 3.25Å; S34-D38 VanDerWaalsContact O-N 3.08Å; S34-E83 WeakPolarHBondContact CB-OE2 3.28Å; S34-E83 PolarHBondContact OG-OE2 3.45Å
35L91.1Very high88.9Confident0 Ų056.6 Ų56.60%032%0.322CS..Hα-helixtrans-69.1-23.3177.3-70.7173.6000113.9L31 I32 Q33 I40 L41 L62 L66 S76 F77 A80L31-L35 VanDerWaalsContact O-CG 3.27Å; L31-L35 WeakPolarHBondContact O-CG 3.42Å; L31-L35 PolarHBondContact O-N 2.93Å; I32-L35 PolarHBondContact O-N 3.21Å; Q33-L35 VanDerWaalsContact C-N 3.35Å; Q33-L35 PolarHBondContact O-N 3.32Å; L35-I40 HydrophobicContact CD2-CB 4.33Å; L35-I40 HydrophobicContact CD2-CG2 4.28Å; L35-I40 WeakPolarHBondContact O-CA 3.48Å; L35-I40 WeakPolarHBondContact O-CB 3.42Å; L35-I40 PolarHBondContact O-N 2.57Å; L35-L41 HydrophobicContact CB-CD1 3.73Å; L35-L41 HydrophobicContact CB-CG 3.96Å; L35-L41 HydrophobicContact CD1-CD1 3.95Å; L35-L41 PolarHBondContact O-N 2.9Å; L35-L62 HydrophobicContact CD1-CD1 3.79Å; L35-L62 HydrophobicContact CD1-CD2 4.16Å; L35-L66 HydrophobicContact CD1-CD2 4.48Å; L35-L66 HydrophobicContact CD2-CD2 4.28Å; L35-S76 WeakPolarHBondContact CD2-OG 3.41Å; L35-F77 HydrophobicContact CD1-CD2 4.42Å; L35-F77 HydrophobicContact CD2-CB 4.31Å; L35-A80 HydrophobicContact CD2-CB 4.44Å; L35-A80 HydrophobicContact CG-CB 4.32Å
36Q90.6Very high88.8Confident65 Ų6556.7 Ų56.730%0.30432%0.323SS..Hα-helixtrans-78-38.7170-73.5176.1-94.800111.7I32 Q33 S34 G39 L41 A46I32-Q36 WeakPolarHBondContact O-CG 3.28Å; I32-Q36 PolarHBondContact O-N 2.7Å; Q33-Q36 PolarHBondContact O-N 3.49Å; Q33-Q36 VanDerWaalsContact O-N 3.17Å; S34-Q36 VanDerWaalsContact C-N 3.3Å; S34-Q36 PolarHBondContact O-N 2.93Å; Q36-G39 WeakPolarHBondContact O-CA 3.25Å; Q36-G39 PolarHBondContact O-N 3.35Å; Q36-L41 HydrophobicContact CG-CB 4.06Å; Q36-A46 HydrophobicContact CG-CB 4.22Å
37A88.1Confident88.7Confident88 Ų8858.6 Ų58.673%0.72733%0.326SS*.Hα-helixtrans-63.2-40.2177.700000112.1Q33 S34 G39Q33-A37 PolarHBondContact O-N 3.12Å; S34-A37 PolarHBondContact O-N 3.31Å; A37-G39 PolarHBondContact O-N 3.04Å
38D87.9Confident88.6Confident95 Ų9560.7 Ų60.751%0.50834%0.339SS..THydrogen-bonded Turntrans-74.50.2172-77.7-15000113.7S34 I40 S76S34-D38 PolarHBondContact O-N 3.25Å; S34-D38 VanDerWaalsContact O-N 3.08Å; D38-I40 HydrophobicContact CB-CG1 3.94Å; D38-I40 PolarHBondContact O-N 2.95Å; D38-S76 VanDerWaalsContact CB-OG 3.27Å; D38-S76 WeakPolarHBondContact CB-OG 3.46Å; D38-S76 WeakPolarHBondContact OD2-CB 3.49Å; D38-S76 PolarHBondContact OD2-OG 2.94Å
39G85.7Confident88.7Confident60 Ų6058.2 Ų58.262%0.61933%0.326SS*.THydrogen-bonded Turntrans71.111.7179.500000115.3Q36 A37Q36-G39 WeakPolarHBondContact O-CA 3.25Å; Q36-G39 PolarHBondContact O-N 3.35Å; A37-G39 PolarHBondContact O-N 3.04Å
40I90.3Very high88.7Confident13 Ų1355.1 Ų55.17%0.06731%0.312CS..SBendtrans-77.1-31.2-178.2-56.3-51.4000111.5L35 D38 L66 R69 A73 S76L35-I40 HydrophobicContact CD2-CB 4.33Å; L35-I40 HydrophobicContact CD2-CG2 4.28Å; L35-I40 WeakPolarHBondContact O-CA 3.48Å; L35-I40 WeakPolarHBondContact O-CB 3.42Å; L35-I40 PolarHBondContact O-N 2.57Å; D38-I40 HydrophobicContact CB-CG1 3.94Å; D38-I40 PolarHBondContact O-N 2.95Å; I40-L66 HydrophobicContact CG2-CD2 3.78Å; I40-R69 HydrophobicContact CG2-CB 3.7Å; I40-R69 HydrophobicContact CG2-CG 4.06Å; I40-R69 WeakPolarHBondContact O-CD 3.34Å; I40-R69 WeakPolarHBondContact O-CG 3.44Å; I40-A73 HydrophobicContact CD1-CB 4.12Å; I40-A73 HydrophobicContact CG2-CB 3.8Å; I40-S76 WeakPolarHBondContact CG1-OG 3.18Å
41L89.7Confident88.7Confident7 Ų754.2 Ų54.24%0.03732%0.32CS..SBendtrans-118.4142.3173.6-63.4178.1000110.9I32 L35 Q36 M45 I49 L62I32-L41 HydrophobicContact CD1-CD1 3.65Å; L35-L41 HydrophobicContact CB-CD1 3.73Å; L35-L41 HydrophobicContact CB-CG 3.96Å; L35-L41 HydrophobicContact CD1-CD1 3.95Å; L35-L41 PolarHBondContact O-N 2.9Å; Q36-L41 HydrophobicContact CG-CB 4.06Å; L41-M45 HydrophobicContact CD2-CB 4.41Å; L41-I49 HydrophobicContact CD1-CD1 3.93Å; L41-I49 HydrophobicContact CD2-CD1 4.12Å; L41-L62 HydrophobicContact CD1-CD1 4.01Å; L41-L62 HydrophobicContact CD2-CD1 4.37Å
42T90.2Very high88.7Confident71 Ų7156.4 Ų56.444%0.43633%0.33SS..  trans-90.7162.1165.673.20000110.5N44 M45 A46T42-N44 PolarHBondContact O-N 2.75Å; T42-M45 HydrophobicContact CG2-CE 3.87Å; T42-M45 HydrophobicContact CG2-SD 4.15Å; T42-M45 CarbonylContact O-C 3.53Å; T42-M45 WeakPolarHBondContact O-CA 3.39Å; T42-M45 WeakPolarHBondContact O-CB 3.3Å; T42-M45 PolarHBondContact O-N 3.44Å; T42-M45 WeakPolarHBondContact OG1-CE 3.41Å; T42-M45 WeakPolarHBondContact OG1-CG 3.48Å; T42-M45 PolarHBondContact OG1-SD 2.93Å; T42-A46 PolarHBondContact O-N 2.88Å
43E86.6Confident88.1Confident144 Ų14463.5 Ų63.567%0.67336%0.363SS*.Hα-helixtrans-51.5-52.9179.6-168166.4-142.400113.1M45 A46 E47E43-M45 PolarHBondContact O-N 3.49Å; E43-M45 VanDerWaalsContact O-N 3.16Å; E43-A46 WeakPolarHBondContact O-CA 3.35Å; E43-A46 WeakPolarHBondContact O-CB 3.43Å; E43-A46 PolarHBondContact O-N 2.99Å; E43-E47 WeakPolarHBondContact O-CG 3.4Å; E43-E47 PolarHBondContact O-N 3.46Å
44N86.5Confident88Confident105 Ų10561.9 Ų61.956%0.56136%0.359SS*.Hα-helixtrans-56.2-33.3173.9-178.8-24.9000113T42 T48T42-N44 PolarHBondContact O-N 2.75Å; N44-T48 VanDerWaalsContact O-CB 3.24Å; N44-T48 WeakPolarHBondContact O-CB 3.13Å; N44-T48 PolarHBondContact O-N 3.04Å; N44-T48 PolarHBondContact O-OG1 3.46Å; N44-T48 PolarHBondContact OD1-OG1 3.42Å
45M87.8Confident87.8Confident44 Ų4463.9 Ų63.922%0.21737%0.373CS..Hα-helixtrans-74-37.6175.7-60.7168.9-163.400111.9L41 T42 E43 T48 I49 R69L41-M45 HydrophobicContact CD2-CB 4.41Å; T42-M45 HydrophobicContact CG2-CE 3.87Å; T42-M45 HydrophobicContact CG2-SD 4.15Å; T42-M45 CarbonylContact O-C 3.53Å; T42-M45 WeakPolarHBondContact O-CA 3.39Å; T42-M45 WeakPolarHBondContact O-CB 3.3Å; T42-M45 PolarHBondContact O-N 3.44Å; T42-M45 WeakPolarHBondContact OG1-CE 3.41Å; T42-M45 WeakPolarHBondContact OG1-CG 3.48Å; T42-M45 PolarHBondContact OG1-SD 2.93Å; E43-M45 PolarHBondContact O-N 3.49Å; E43-M45 VanDerWaalsContact O-N 3.16Å; M45-T48 PolarHBondContact O-N 2.7Å; M45-I49 WeakPolarHBondContact O-CD1 3.32Å; M45-I49 WeakPolarHBondContact O-CG1 3.3Å; M45-I49 PolarHBondContact O-N 3.35Å; M45-R69 PolarHBondContact SD-NH2 3.26Å
46A87.9Confident87.5Confident7 Ų769.4 Ų69.46%0.05840%0.399CS..Hα-helixtrans-62.3-48.5172.100000111.1I32 Q36 T42 E43 T48 I49 M50I32-A46 HydrophobicContact CG2-CB 3.37Å; Q36-A46 HydrophobicContact CG-CB 4.22Å; T42-A46 PolarHBondContact O-N 2.88Å; E43-A46 WeakPolarHBondContact O-CA 3.35Å; E43-A46 WeakPolarHBondContact O-CB 3.43Å; E43-A46 PolarHBondContact O-N 2.99Å; A46-T48 PolarHBondContact O-N 2.86Å; A46-I49 PolarHBondContact O-N 3.38Å; A46-M50 WeakPolarHBondContact O-CB 2.98Å; A46-M50 WeakPolarHBondContact O-CG 3.4Å; A46-M50 PolarHBondContact O-N 2.92Å
47E87.5Confident87.3Confident123 Ų12370.4 Ų70.458%0.57540%0.403SS*.Hα-helixtrans-55.5-50.7172.8-68178.1141.500111.4E43 I49 M50 A51E43-E47 WeakPolarHBondContact O-CG 3.4Å; E43-E47 PolarHBondContact O-N 3.46Å; E47-I49 VanDerWaalsContact C-N 3.28Å; E47-I49 PolarHBondContact O-N 3.37Å; E47-M50 PolarHBondContact O-N 3.15Å; E47-A51 VanDerWaalsContact O-CB 3.22Å; E47-A51 WeakPolarHBondContact O-CB 3.42Å; E47-A51 PolarHBondContact O-N 3.42Å
48T87.1Confident87.4Confident50 Ų5069.7 Ų69.731%0.30738%0.381SS..Hα-helixtrans-60.2-35.1178.8-64.10000112.6N44 M45 A46N44-T48 VanDerWaalsContact O-CB 3.24Å; N44-T48 WeakPolarHBondContact O-CB 3.13Å; N44-T48 PolarHBondContact O-N 3.04Å; N44-T48 PolarHBondContact O-OG1 3.46Å; N44-T48 PolarHBondContact OD1-OG1 3.42Å; M45-T48 PolarHBondContact O-N 2.7Å; A46-T48 PolarHBondContact O-N 2.86Å
49I88.7Confident87.5Confident0 Ų065.2 Ų65.20%036%0.357CS..Hα-helixtrans-72.2-50.6174.6-68.5159.6000109.8V27 I32 L41 M45 A46 E47 A51 E52 R58 R61 L62 L65V27-I49 HydrophobicContact CG1-CG2 3.81Å; I32-I49 HydrophobicContact CD1-CB 4.44Å; I32-I49 HydrophobicContact CD1-CD1 4Å; I32-I49 HydrophobicContact CD1-CG2 4.01Å; L41-I49 HydrophobicContact CD1-CD1 3.93Å; L41-I49 HydrophobicContact CD2-CD1 4.12Å; M45-I49 WeakPolarHBondContact O-CD1 3.32Å; M45-I49 WeakPolarHBondContact O-CG1 3.3Å; M45-I49 PolarHBondContact O-N 3.35Å; A46-I49 PolarHBondContact O-N 3.38Å; E47-I49 VanDerWaalsContact C-N 3.28Å; E47-I49 PolarHBondContact O-N 3.37Å; I49-A51 VanDerWaalsContact C-N 3.34Å; I49-A51 PolarHBondContact O-N 2.94Å; I49-E52 WeakPolarHBondContact O-CB 3.31Å; I49-E52 PolarHBondContact O-N 3.31Å; I49-R58 HydrophobicContact CG2-CB 4.2Å; I49-R58 WeakPolarHBondContact O-CG 3.26Å; I49-R61 HydrophobicContact CG1-CB 4.38Å; I49-R61 HydrophobicContact CG1-CG 3.93Å; I49-L62 HydrophobicContact CD1-CB 4.35Å; I49-L62 HydrophobicContact CD1-CD1 4.03Å; I49-L65 HydrophobicContact CD1-CD1 3.89Å; I49-L65 HydrophobicContact CG1-CD1 3.93Å
50M87.1Confident87.6Confident58 Ų5869 Ų6929%0.28635%0.353SS..Hα-helixtrans-68.6-31.4-173.2-68.3-62.9-84.300113.2E29 I32 A46 E47 E52 R58E29-M50 HydrophobicContact CB-CE 4.25Å; I32-M50 HydrophobicContact CG1-SD 4.17Å; A46-M50 WeakPolarHBondContact O-CB 2.98Å; A46-M50 WeakPolarHBondContact O-CG 3.4Å; A46-M50 PolarHBondContact O-N 2.92Å; E47-M50 PolarHBondContact O-N 3.15Å; M50-E52 PolarHBondContact O-N 2.84Å; M50-E52 VanDerWaalsContact O-N 3.17Å; M50-R58 PolarHBondContact O-NE 3.02Å; M50-R58 VanDerWaalsContact O-NE 3.08Å; M50-R58 PolarHBondContact O-NH2 3.31Å
51A88.3Confident87.5Confident84 Ų8472.2 Ų72.269%0.69436%0.364SS*.THydrogen-bonded Turntrans-63.1-14.8174.700000114.2E47 I49E47-A51 VanDerWaalsContact O-CB 3.22Å; E47-A51 WeakPolarHBondContact O-CB 3.42Å; E47-A51 PolarHBondContact O-N 3.42Å; I49-A51 VanDerWaalsContact C-N 3.34Å; I49-A51 PolarHBondContact O-N 2.94Å
52E89.9Confident87.5Confident46 Ų4671.9 Ų71.922%0.21536%0.362CS..SBendtrans-63.3142.3176.5-78.1-72.9-167.300112.6I49 M50 T54 K57 R58 R61I49-E52 WeakPolarHBondContact O-CB 3.31Å; I49-E52 PolarHBondContact O-N 3.31Å; M50-E52 PolarHBondContact O-N 2.84Å; M50-E52 VanDerWaalsContact O-N 3.17Å; E52-T54 PolarHBondContact O-N 2.88Å; E52-K57 HydrophobicContact CB-CB 3.86Å; E52-K57 HydrophobicContact CG-CB 4.09Å; E52-K57 WeakPolarHBondContact OE2-CD 3.46Å; E52-R58 HydrophobicContact CB-CG 3.82Å; E52-R58 PolarHBondContact O-NE 3.48Å; E52-R58 VanDerWaalsContact O-NE 3.1Å; E52-R58 PolarHBondContact O-NH2 3.33Å; E52-R61 HydrophobicContact CG-CB 4.5Å
53Q80.9Confident87.5Confident154 Ų15469.4 Ų69.472%0.7235%0.346SS*.SBendtrans-73-21.9-167.1-66.1161.3-19.300114.4
54T86.4Confident87.6Confident58 Ų5865.7 Ų65.736%0.35633%0.331SS..SBendtrans-137.8149.9-177.574.20000111.1E52 Q56 K57 R58E52-T54 PolarHBondContact O-N 2.88Å; T54-Q56 PolarHBondContact O-N 2.95Å; T54-K57 PolarHBondContact O-N 2.97Å; T54-K57 WeakPolarHBondContact OG1-CG 3.18Å; T54-K57 PolarHBondContact OG1-N 3.43Å; T54-R58 WeakPolarHBondContact O-CG 3.46Å; T54-R58 PolarHBondContact O-N 3.38Å
55S85.1Confident87.5Confident69 Ų6961.7 Ų61.748%0.48331%0.31SS..Hα-helixtrans-55.2-33.4176.550.80000113.2R58 S59S55-R58 PolarHBondContact O-N 2.9Å; S55-S59 WeakPolarHBondContact O-CB 3.27Å; S55-S59 PolarHBondContact O-N 2.67Å; S55-S59 PolarHBondContact O-OG 3.28Å
56Q85.6Confident87.5Confident116 Ų11659.6 Ų59.654%0.54230%0.299SS..Hα-helixtrans-67-42.2176-64.3167.6-12.500111.6T54 S59 W60T54-Q56 PolarHBondContact O-N 2.95Å; Q56-S59 PolarHBondContact O-N 3.11Å; Q56-W60 WeakPolarHBondContact O-CB 3.48Å; Q56-W60 PolarHBondContact O-N 2.99Å
57K85.9Confident87.5Confident87 Ų8760.7 Ų60.738%0.37831%0.305SS..Hα-helixtrans-65.9-43.2172.9-71.7-171.4-176.3-175.80111.7E52 T54 S59 W60 R61E52-K57 HydrophobicContact CB-CB 3.86Å; E52-K57 HydrophobicContact CG-CB 4.09Å; E52-K57 WeakPolarHBondContact OE2-CD 3.46Å; T54-K57 PolarHBondContact O-N 2.97Å; T54-K57 WeakPolarHBondContact OG1-CG 3.18Å; T54-K57 PolarHBondContact OG1-N 3.43Å; K57-S59 VanDerWaalsContact C-N 3.34Å; K57-S59 PolarHBondContact O-N 3.28Å; K57-W60 PolarHBondContact O-N 3.08Å; K57-R61 VanDerWaalsContact O-CB 3.28Å; K57-R61 WeakPolarHBondContact O-CB 3.3Å; K57-R61 PolarHBondContact O-N 2.71Å
58R90.4Very high87.4Confident73 Ų7361.5 Ų61.528%0.27531%0.307SS..Hα-helixtrans-55.1-49.3173.7-62.3-173-176.5138.412.1111.5V27 I49 M50 E52 T54 S55 R61 L62V27-R58 HydrophobicContact CB-CB 3.88Å; V27-R58 HydrophobicContact CG1-CB 4.19Å; V27-R58 HydrophobicContact CG2-CB 4.36Å; I49-R58 HydrophobicContact CG2-CB 4.2Å; I49-R58 WeakPolarHBondContact O-CG 3.26Å; M50-R58 PolarHBondContact O-NE 3.02Å; M50-R58 VanDerWaalsContact O-NE 3.08Å; M50-R58 PolarHBondContact O-NH2 3.31Å; E52-R58 HydrophobicContact CB-CG 3.82Å; E52-R58 PolarHBondContact O-NE 3.48Å; E52-R58 VanDerWaalsContact O-NE 3.1Å; E52-R58 PolarHBondContact O-NH2 3.33Å; T54-R58 WeakPolarHBondContact O-CG 3.46Å; T54-R58 PolarHBondContact O-N 3.38Å; S55-R58 PolarHBondContact O-N 2.9Å; R58-R61 PolarHBondContact O-N 2.69Å; R58-L62 WeakPolarHBondContact O-CB 3.4Å; R58-L62 PolarHBondContact O-N 3.07Å
59S89.4Confident87.2Confident1 Ų162.8 Ų62.81%0.00731%0.306CS..Hα-helixtrans-60.6-48.1178.4-59.40000112.3L25 S55 Q56 K57 L62 L63L25-S59 PolarHBondContact O-OG 3.02Å; S55-S59 WeakPolarHBondContact O-CB 3.27Å; S55-S59 PolarHBondContact O-N 2.67Å; S55-S59 PolarHBondContact O-OG 3.28Å; Q56-S59 PolarHBondContact O-N 3.11Å; K57-S59 VanDerWaalsContact C-N 3.34Å; K57-S59 PolarHBondContact O-N 3.28Å; S59-L62 PolarHBondContact O-N 3.29Å; S59-L63 WeakPolarHBondContact O-CB 3.45Å; S59-L63 WeakPolarHBondContact O-CD1 3.45Å; S59-L63 WeakPolarHBondContact O-CG 3.09Å; S59-L63 PolarHBondContact O-N 2.89Å
60W87.4Confident86.9Confident138 Ų13863.6 Ų63.652%0.52331%0.314SS..Hα-helixtrans-62.7-42.9176.8-179.684.2000112.3Q56 K57 L62 L63 L64Q56-W60 WeakPolarHBondContact O-CB 3.48Å; Q56-W60 PolarHBondContact O-N 2.99Å; K57-W60 PolarHBondContact O-N 3.08Å; W60-L62 PolarHBondContact O-N 2.96Å; W60-L63 PolarHBondContact O-N 3.38Å; W60-L64 HydrophobicContact CH2-CD2 3.75Å; W60-L64 HydrophobicContact CZ2-CD2 4.19Å; W60-L64 HydrophobicContact CZ3-CD2 3.99Å; W60-L64 WeakPolarHBondContact O-CB 3.27Å; W60-L64 PolarHBondContact O-N 2.91Å
61R88.3Confident86.5Confident81 Ų8163.9 Ų63.931%0.30632%0.32SS..Hα-helixtrans-62.5-42.9178.5-168.264.9171.8176.7-4111.4I49 E52 K57 R58 L64 L65I49-R61 HydrophobicContact CG1-CB 4.38Å; I49-R61 HydrophobicContact CG1-CG 3.93Å; E52-R61 HydrophobicContact CG-CB 4.5Å; K57-R61 VanDerWaalsContact O-CB 3.28Å; K57-R61 WeakPolarHBondContact O-CB 3.3Å; K57-R61 PolarHBondContact O-N 2.71Å; R58-R61 PolarHBondContact O-N 2.69Å; R61-L64 PolarHBondContact O-N 3.17Å; R61-L65 HydrophobicContact CG-CD1 4.24Å; R61-L65 WeakPolarHBondContact O-CD1 3.37Å; R61-L65 VanDerWaalsContact O-CG 3.23Å; R61-L65 WeakPolarHBondContact O-CG 3.24Å; R61-L65 PolarHBondContact O-N 3Å
62L90.6Very high86.4Confident0 Ų065.2 Ų65.20%031%0.313CS..Hα-helixtrans-62.7-48.6174.3177.858.2000111.8L25 V27 L31 I32 L35 L41 I49 R58 S59 W60 L64 L65 L66 F77L25-L62 HydrophobicContact CD2-CD2 4.27Å; V27-L62 HydrophobicContact CG1-CD2 4.27Å; V27-L62 HydrophobicContact CG2-CB 4.4Å; V27-L62 HydrophobicContact CG2-CD2 3.74Å; L31-L62 HydrophobicContact CD2-CD2 3.74Å; I32-L62 HydrophobicContact CD1-CD1 4.5Å; L35-L62 HydrophobicContact CD1-CD1 3.79Å; L35-L62 HydrophobicContact CD1-CD2 4.16Å; L41-L62 HydrophobicContact CD1-CD1 4.01Å; L41-L62 HydrophobicContact CD2-CD1 4.37Å; I49-L62 HydrophobicContact CD1-CB 4.35Å; I49-L62 HydrophobicContact CD1-CD1 4.03Å; R58-L62 WeakPolarHBondContact O-CB 3.4Å; R58-L62 PolarHBondContact O-N 3.07Å; S59-L62 PolarHBondContact O-N 3.29Å; W60-L62 PolarHBondContact O-N 2.96Å; L62-L64 VanDerWaalsContact C-N 3.27Å; L62-L64 PolarHBondContact O-N 3.22Å; L62-L65 PolarHBondContact O-N 2.94Å; L62-L66 HydrophobicContact CD1-CD1 3.96Å; L62-L66 HydrophobicContact CD1-CD2 4.3Å; L62-L66 HydrophobicContact CD1-CG 3.84Å; L62-L66 HydrophobicContact CG-CD1 3.85Å; L62-L66 HydrophobicContact CG-CG 4.23Å; L62-L66 WeakPolarHBondContact O-CG 3.39Å; L62-L66 PolarHBondContact O-N 3.28Å; L62-F77 HydrophobicContact CD2-CE2 4.21Å
63L90.1Very high86.3Confident19 Ų1963 Ų6310%0.09930%0.302CS..Hα-helixtrans-65.5-26.2179.4-68.6164.3000113.5L14 L21 L25 S59 W60 P67 F77L14-L63 HydrophobicContact CD2-CD2 4.34Å; L21-L63 HydrophobicContact CB-CD1 3.65Å; L21-L63 HydrophobicContact CB-CD2 4.36Å; L21-L63 HydrophobicContact CD1-CD2 4.02Å; L25-L63 HydrophobicContact CD2-CG 4.48Å; S59-L63 WeakPolarHBondContact O-CB 3.45Å; S59-L63 WeakPolarHBondContact O-CD1 3.45Å; S59-L63 WeakPolarHBondContact O-CG 3.09Å; S59-L63 PolarHBondContact O-N 2.89Å; W60-L63 PolarHBondContact O-N 3.38Å; L63-P67 WeakPolarHBondContact O-CD 3.21Å; L63-F77 HydrophobicContact CD2-CZ 4.39Å
64L88Confident86.8Confident66 Ų6657 Ų5735%0.34627%0.274SS..Hα-helixtrans-73.8-30.6172.1-179.165.7000112.6W60 R61 L62W60-L64 HydrophobicContact CH2-CD2 3.75Å; W60-L64 HydrophobicContact CZ2-CD2 4.19Å; W60-L64 HydrophobicContact CZ3-CD2 3.99Å; W60-L64 WeakPolarHBondContact O-CB 3.27Å; W60-L64 PolarHBondContact O-N 2.91Å; R61-L64 PolarHBondContact O-N 3.17Å; L62-L64 VanDerWaalsContact C-N 3.27Å; L62-L64 PolarHBondContact O-N 3.22Å
65L86.2Confident86.9Confident22 Ų2260.6 Ų60.612%0.11529%0.286CS..Hα-helixtrans-87.3-44.4-176.5-68.5167.1000112.2I49 R61 L62 K68I49-L65 HydrophobicContact CD1-CD1 3.89Å; I49-L65 HydrophobicContact CG1-CD1 3.93Å; R61-L65 HydrophobicContact CG-CD1 4.24Å; R61-L65 WeakPolarHBondContact O-CD1 3.37Å; R61-L65 VanDerWaalsContact O-CG 3.23Å; R61-L65 WeakPolarHBondContact O-CG 3.24Å; R61-L65 PolarHBondContact O-N 3Å; L62-L65 PolarHBondContact O-N 2.94Å; L65-K68 WeakPolarHBondContact O-CB 3.41Å; L65-K68 PolarHBondContact O-N 2.96Å
66L87.5Confident87.2Confident0 Ų057.6 Ų57.60%027%0.266CS..G310 helixtrans-48.2-46.7-175.9-79.4168000114.7M6 L35 I40 L62 K68 R69 F77M6-L66 HydrophobicContact CE-CB 4.14Å; L35-L66 HydrophobicContact CD1-CD2 4.48Å; L35-L66 HydrophobicContact CD2-CD2 4.28Å; I40-L66 HydrophobicContact CG2-CD2 3.78Å; L62-L66 HydrophobicContact CD1-CD1 3.96Å; L62-L66 HydrophobicContact CD1-CD2 4.3Å; L62-L66 HydrophobicContact CD1-CG 3.84Å; L62-L66 HydrophobicContact CG-CD1 3.85Å; L62-L66 HydrophobicContact CG-CG 4.23Å; L62-L66 WeakPolarHBondContact O-CG 3.39Å; L62-L66 PolarHBondContact O-N 3.28Å; L66-K68 PolarHBondContact O-N 3.25Å; L66-R69 PolarHBondContact O-N 3.44Å; L66-F77 HydrophobicContact CD1-CB 4.17Å; L66-F77 HydrophobicContact CD1-CD1 4.03Å; L66-F77 HydrophobicContact CD1-CD2 3.57Å; L66-F77 HydrophobicContact CD1-CE1 4.3Å; L66-F77 HydrophobicContact CD1-CE2 3.87Å; L66-F77 HydrophobicContact CD1-CG 3.65Å; L66-F77 HydrophobicContact CD1-CZ 4.23Å; L66-F77 HydrophobicContact CD2-CB 4.18Å
67P87.2Confident87.5Confident29 Ų2952.1 Ų52.119%0.18824%0.24CC..G310 helixtrans-59.8-16.3-179.5-26.436.4000115.3M6 K11 L63M6-P67 PolarHBondContact N-O 3.29Å; M6-P67 VanDerWaalsContact N-O 3.11Å; K11-P67 HydrophobicContact CD-CB 4.07Å; K11-P67 HydrophobicContact CG-CB 4.22Å; L63-P67 WeakPolarHBondContact O-CD 3.21Å
68K85.1Confident87.7Confident140 Ų14048.5 Ų48.561%0.60923%0.226SC*.G310 helixtrans-95.81.4-178.6-52.5-176.8-176.3-1780113.5L65 L66L65-K68 WeakPolarHBondContact O-CB 3.41Å; L65-K68 PolarHBondContact O-N 2.96Å; L66-K68 PolarHBondContact O-N 3.25Å
69R83Confident87.7Confident78 Ų7847.2 Ų47.229%0.29423%0.228SC..SBendtrans-103.525.9-169.4-56.2-60.7170.9-156.1-6.7115.5I40 M45 L66 A73I40-R69 HydrophobicContact CG2-CB 3.7Å; I40-R69 HydrophobicContact CG2-CG 4.06Å; I40-R69 WeakPolarHBondContact O-CD 3.34Å; I40-R69 WeakPolarHBondContact O-CG 3.44Å; M45-R69 PolarHBondContact SD-NH2 3.26Å; L66-R69 PolarHBondContact O-N 3.44Å; R69-A73 HydrophobicContact CB-CB 3.73Å
70G82.3Confident87.7Confident16 Ų1647.2 Ų47.217%0.16523%0.228CC..  trans83.3-178.6179.400000113.9G5 M6 A73G5-G70 CarbonylContact C-O 3.57Å; G5-G70 CarbonylContact O-C 3.13Å; M6-G70 VanDerWaalsContact CA-O 3.26Å; M6-G70 WeakPolarHBondContact CA-O 3.19Å; M6-G70 PolarHBondContact N-O 3.41Å; G70-A73 WeakPolarHBondContact O-CB 3.28Å
71P80.1Confident87.9Confident64 Ų6440.6 Ų40.642%0.41620%0.203SC..SBendtrans-66.9-44.1-172.624.4-33.1000112.8A73P71-A73 PolarHBondContact O-N 2.84Å
72E84.8Confident87.9Confident113 Ų11341.1 Ų41.153%0.52821%0.207SC..THydrogen-bonded Turntrans-65.9-19.5-175.8-53.7-46.9125.100113.9F74 Q75 S76E72-F74 PolarHBondContact O-N 3.28Å; E72-Q75 PolarHBondContact O-N 3.38Å; E72-S76 PolarHBondContact O-N 3.39Å
73A88.9Confident87.8Confident0 Ų047 Ų470%024%0.235CC..Hα-helixtrans-56.2-26.9-176.300000114.3M6 I40 R69 G70 P71 F77M6-A73 HydrophobicContact CE-CB 4.05Å; I40-A73 HydrophobicContact CD1-CB 4.12Å; I40-A73 HydrophobicContact CG2-CB 3.8Å; R69-A73 HydrophobicContact CB-CB 3.73Å; G70-A73 WeakPolarHBondContact O-CB 3.28Å; P71-A73 PolarHBondContact O-N 2.84Å; A73-F77 VanDerWaalsContact O-CB 3.25Å; A73-F77 WeakPolarHBondContact O-CB 3.35Å; A73-F77 PolarHBondContact O-N 2.91Å
74F89.9Confident87.7Confident28 Ų2847.2 Ų47.212%0.12324%0.237CC..Hα-helixtrans-77.7-41.1175.1-177.8-105000112.2M6 D10 A13 L14 E72 C78 I93M6-F74 HydrophobicContact CE-CB 3.89Å; M6-F74 HydrophobicContact CG-CB 4.07Å; M6-F74 HydrophobicContact SD-CB 4.04Å; M6-F74 HydrophobicContact SD-CD2 4.19Å; D10-F74 HydrophobicContact CB-CB 3.96Å; D10-F74 HydrophobicContact CB-CD1 3.79Å; D10-F74 HydrophobicContact CB-CD2 3.69Å; D10-F74 HydrophobicContact CB-CE1 4.09Å; D10-F74 HydrophobicContact CB-CE2 3.99Å; D10-F74 HydrophobicContact CB-CG 3.55Å; D10-F74 HydrophobicContact CB-CZ 4.16Å; D10-F74 VanDerWaalsContact CG-CD1 3.49Å; D10-F74 VanDerWaalsContact OD1-CE1 3.3Å; D10-F74 WeakPolarHBondContact OD1-CE1 3.46Å; A13-F74 HydrophobicContact CB-CE2 4.37Å; A13-F74 HydrophobicContact CB-CZ 4.39Å; L14-F74 HydrophobicContact CD1-CD2 4.32Å; L14-F74 HydrophobicContact CD2-CD2 4.4Å; L14-F74 HydrophobicContact CD2-CE2 4.2Å; L14-F74 HydrophobicContact CG-CD2 4.14Å; L14-F74 HydrophobicContact CG-CE2 4.12Å; E72-F74 PolarHBondContact O-N 3.28Å; F74-C78 WeakPolarHBondContact O-CB 3.2Å; F74-C78 PolarHBondContact O-N 2.97Å; F74-C78 PolarHBondContact O-SG 3.32Å; F74-I93 HydrophobicContact CE2-CG2 3.55Å; F74-I93 HydrophobicContact CZ-CG2 3.41Å; F74-I93 VanDerWaalsContact CZ-CG2 3.41Å
75Q89.2Confident87.8Confident132 Ų13252.5 Ų52.562%0.61726%0.259SS*.Hα-helixtrans-70-44179.4-174.8168.5-62.300110.9E72 C78 S79E72-Q75 PolarHBondContact O-N 3.38Å; Q75-C78 CarbonylContact O-C 3.54Å; Q75-C78 WeakPolarHBondContact O-CA 3.34Å; Q75-C78 WeakPolarHBondContact O-CB 3.37Å; Q75-C78 PolarHBondContact O-N 3.42Å; Q75-C78 VanDerWaalsContact O-N 3.15Å; Q75-S79 PolarHBondContact O-N 2.92Å; Q75-S79 PolarHBondContact O-OG 3.44Å
76S91.1Very high88Confident7 Ų752 Ų525%0.04926%0.257CS..Hα-helixtrans-56.4-50171.91720000111.9L35 D38 I40 E72 C78 S79 A80L35-S76 WeakPolarHBondContact CD2-OG 3.41Å; D38-S76 VanDerWaalsContact CB-OG 3.27Å; D38-S76 WeakPolarHBondContact CB-OG 3.46Å; D38-S76 WeakPolarHBondContact OD2-CB 3.49Å; D38-S76 PolarHBondContact OD2-OG 2.94Å; I40-S76 WeakPolarHBondContact CG1-OG 3.18Å; E72-S76 PolarHBondContact O-N 3.39Å; S76-C78 VanDerWaalsContact C-N 3.29Å; S76-C78 PolarHBondContact O-N 2.77Å; S76-S79 WeakPolarHBondContact O-CB 3.39Å; S76-S79 PolarHBondContact O-N 3.42Å; S76-A80 PolarHBondContact O-N 3.32Å
77F93Very high87.9Confident0 Ų055.8 Ų55.80%027%0.274CS..Hα-helixtrans-59.7-38.5174.3179.9-118000112.7L14 L25 L35 L62 L63 L66 A73 S79 A80 L81 I93L14-F77 HydrophobicContact CD2-CD1 4.12Å; L14-F77 HydrophobicContact CD2-CE1 3.85Å; L25-F77 HydrophobicContact CD1-CE2 4.26Å; L25-F77 HydrophobicContact CD1-CZ 4.12Å; L25-F77 HydrophobicContact CD2-CE2 4.35Å; L25-F77 HydrophobicContact CD2-CZ 4.16Å; L35-F77 HydrophobicContact CD1-CD2 4.42Å; L35-F77 HydrophobicContact CD2-CB 4.31Å; L62-F77 HydrophobicContact CD2-CE2 4.21Å; L63-F77 HydrophobicContact CD2-CZ 4.39Å; L66-F77 HydrophobicContact CD1-CB 4.17Å; L66-F77 HydrophobicContact CD1-CD1 4.03Å; L66-F77 HydrophobicContact CD1-CD2 3.57Å; L66-F77 HydrophobicContact CD1-CE1 4.3Å; L66-F77 HydrophobicContact CD1-CE2 3.87Å; L66-F77 HydrophobicContact CD1-CG 3.65Å; L66-F77 HydrophobicContact CD1-CZ 4.23Å; L66-F77 HydrophobicContact CD2-CB 4.18Å; A73-F77 VanDerWaalsContact O-CB 3.25Å; A73-F77 WeakPolarHBondContact O-CB 3.35Å; A73-F77 PolarHBondContact O-N 2.91Å; F77-S79 VanDerWaalsContact C-N 3.31Å; F77-S79 PolarHBondContact O-N 3.48Å; F77-A80 PolarHBondContact O-N 2.6Å; F77-L81 HydrophobicContact CD1-CD1 4.09Å; F77-L81 HydrophobicContact CD2-CG 4.45Å; F77-L81 HydrophobicContact CE1-CD1 3.68Å; F77-L81 HydrophobicContact CE1-CG 4.31Å; F77-L81 HydrophobicContact CE2-CD1 4.39Å; F77-L81 HydrophobicContact CE2-CD2 4.24Å; F77-L81 HydrophobicContact CE2-CG 4.13Å; F77-L81 HydrophobicContact CZ-CD1 3.85Å; F77-L81 HydrophobicContact CZ-CD2 4.13Å; F77-L81 HydrophobicContact CZ-CG 4.06Å; F77-L81 WeakPolarHBondContact O-CB 3.23Å; F77-L81 VanDerWaalsContact O-CG 3.3Å; F77-L81 WeakPolarHBondContact O-CG 3.36Å; F77-L81 PolarHBondContact O-N 3.25Å; F77-I93 HydrophobicContact CE1-CD1 4.03Å
78C90.1Very high87.9Confident12 Ų1259.4 Ų59.48%0.08129%0.288CS..Hα-helixtrans-67.2-26.7174-73.90000114F74 Q75 S76 K82 Y90F74-C78 WeakPolarHBondContact O-CB 3.2Å; F74-C78 PolarHBondContact O-N 2.97Å; F74-C78 PolarHBondContact O-SG 3.32Å; Q75-C78 CarbonylContact O-C 3.54Å; Q75-C78 WeakPolarHBondContact O-CA 3.34Å; Q75-C78 WeakPolarHBondContact O-CB 3.37Å; Q75-C78 PolarHBondContact O-N 3.42Å; Q75-C78 VanDerWaalsContact O-N 3.15Å; S76-C78 VanDerWaalsContact C-N 3.29Å; S76-C78 PolarHBondContact O-N 2.77Å; C78-K82 WeakPolarHBondContact O-CG 3.36Å; C78-Y90 HydrophobicContact CB-CD2 3.72Å; C78-Y90 HydrophobicContact CB-CE2 3.84Å
79S88.9Confident88.1Confident46 Ų4652.7 Ų52.732%0.32226%0.259SS..Hα-helixtrans-76-48.7171.1-63.70000111.2Q75 S76 F77 L81 K82 E83Q75-S79 PolarHBondContact O-N 2.92Å; Q75-S79 PolarHBondContact O-OG 3.44Å; S76-S79 WeakPolarHBondContact O-CB 3.39Å; S76-S79 PolarHBondContact O-N 3.42Å; F77-S79 VanDerWaalsContact C-N 3.31Å; F77-S79 PolarHBondContact O-N 3.48Å; S79-L81 VanDerWaalsContact C-N 3.25Å; S79-L81 PolarHBondContact O-N 3.1Å; S79-K82 WeakPolarHBondContact O-CA 3.33Å; S79-K82 WeakPolarHBondContact O-CB 3.45Å; S79-K82 PolarHBondContact O-N 3.22Å; S79-E83 PolarHBondContact O-N 3.24Å
80A91.1Very high88.3Confident0 Ų051.7 Ų51.70%026%0.256CS..Hα-helixtrans-59.5-34.1178.800000112.5L31 L35 S76 F77 K82 E83 T84L31-A80 HydrophobicContact CD1-CB 3.72Å; L35-A80 HydrophobicContact CD2-CB 4.44Å; L35-A80 HydrophobicContact CG-CB 4.32Å; S76-A80 PolarHBondContact O-N 3.32Å; F77-A80 PolarHBondContact O-N 2.6Å; A80-K82 VanDerWaalsContact C-N 3.26Å; A80-K82 PolarHBondContact O-N 3.01Å; A80-E83 PolarHBondContact O-N 3.32Å; A80-T84 PolarHBondContact O-N 3.02Å; A80-T84 PolarHBondContact O-OG1 2.91Å
81L91.3Very high88.4Confident0 Ų053.3 Ų53.30%026%0.261CS..Hα-helixtrans-64.5-23.9171-77.4177.2000114.1L25 F77 S79 Q86 Q87 L89 I93L25-L81 HydrophobicContact CD1-CD2 3.53Å; F77-L81 HydrophobicContact CD1-CD1 4.09Å; F77-L81 HydrophobicContact CD2-CG 4.45Å; F77-L81 HydrophobicContact CE1-CD1 3.68Å; F77-L81 HydrophobicContact CE1-CG 4.31Å; F77-L81 HydrophobicContact CE2-CD1 4.39Å; F77-L81 HydrophobicContact CE2-CD2 4.24Å; F77-L81 HydrophobicContact CE2-CG 4.13Å; F77-L81 HydrophobicContact CZ-CD1 3.85Å; F77-L81 HydrophobicContact CZ-CD2 4.13Å; F77-L81 HydrophobicContact CZ-CG 4.06Å; F77-L81 WeakPolarHBondContact O-CB 3.23Å; F77-L81 VanDerWaalsContact O-CG 3.3Å; F77-L81 WeakPolarHBondContact O-CG 3.36Å; F77-L81 PolarHBondContact O-N 3.25Å; S79-L81 VanDerWaalsContact C-N 3.25Å; S79-L81 PolarHBondContact O-N 3.1Å; L81-Q86 HydrophobicContact CD2-CB 3.8Å; L81-Q86 CarbonylContact O-C 3.57Å; L81-Q86 WeakPolarHBondContact O-CA 3.36Å; L81-Q86 WeakPolarHBondContact O-CB 3.48Å; L81-Q86 PolarHBondContact O-N 3.18Å; L81-Q87 PolarHBondContact O-N 2.84Å; L81-L89 HydrophobicContact CD1-CB 4.27Å; L81-L89 HydrophobicContact CD2-CB 4.2Å; L81-L89 HydrophobicContact CD2-CD1 4.26Å; L81-I93 HydrophobicContact CD1-CD1 3.98Å
82K87.3Confident88.7Confident91 Ų9153.5 Ų53.540%0.39626%0.258SS..Hα-helixtrans-86.9-41.5175.5-62.1176.3-175.7174.40111.2C78 S79 A80 T84 E85 Y90C78-K82 WeakPolarHBondContact O-CG 3.36Å; S79-K82 WeakPolarHBondContact O-CA 3.33Å; S79-K82 WeakPolarHBondContact O-CB 3.45Å; S79-K82 PolarHBondContact O-N 3.22Å; A80-K82 VanDerWaalsContact C-N 3.26Å; A80-K82 PolarHBondContact O-N 3.01Å; K82-T84 VanDerWaalsContact C-N 3.26Å; K82-T84 PolarHBondContact O-N 2.94Å; K82-E85 PolarHBondContact O-N 3.06Å; K82-E85 VanDerWaalsContact O-N 3.11Å; K82-Y90 VanDerWaalsContact CE-CD2 3.43Å; K82-Y90 VanDerWaalsContact CE-CE1 3.47Å; K82-Y90 HydrophobicContact CG-CG 4.41Å; K82-Y90 PolarHBondContact NZ-OH 3.43Å
83E88.2Confident88.8Confident125 Ų12548.3 Ų48.358%0.58423%0.234SC*.Hα-helixtrans-62-33177.2-69.9167.2-169.700112.4S34 S79 A80 E85S34-E83 WeakPolarHBondContact CB-OE2 3.28Å; S34-E83 PolarHBondContact OG-OE2 3.45Å; S79-E83 PolarHBondContact O-N 3.24Å; A80-E83 PolarHBondContact O-N 3.32Å; E83-E85 VanDerWaalsContact C-N 3.34Å
84T89.6Confident88.3Confident22 Ų2250.7 Ų50.714%0.13525%0.254CS..THydrogen-bonded Turntrans-91.917.6175.157.10000114.2L30 L31 A80 K82 Q86L30-T84 HydrophobicContact CB-CG2 4.01Å; L31-T84 HydrophobicContact CB-CG2 3.96Å; L31-T84 HydrophobicContact CD1-CG2 4.08Å; A80-T84 PolarHBondContact O-N 3.02Å; A80-T84 PolarHBondContact O-OG1 2.91Å; K82-T84 VanDerWaalsContact C-N 3.26Å; K82-T84 PolarHBondContact O-N 2.94Å; T84-Q86 WeakPolarHBondContact O-CG 3.41Å; T84-Q86 PolarHBondContact O-N 2.9Å; T84-Q86 PolarHBondContact OG1-NE2 2.94Å
85E88.4Confident87.2Confident177 Ų17756 Ų5683%0.82728%0.279SS*.THydrogen-bonded Turntrans60.88-179.4-53.2-169.8162.500115.7K82 E83 Q87K82-E85 PolarHBondContact O-N 3.06Å; K82-E85 VanDerWaalsContact O-N 3.11Å; E83-E85 VanDerWaalsContact C-N 3.34Å; E85-Q87 PolarHBondContact O-N 3.34Å
86Q90.5Very high85.6Confident13 Ų1351.9 Ų51.96%0.06127%0.265CS..  trans-78.434.1179-60-175.280.800113.6V26 L81 T84 H88 L89 Y90V26-Q86 PolarHBondContact O-NE2 3.48Å; L81-Q86 HydrophobicContact CD2-CB 3.8Å; L81-Q86 CarbonylContact O-C 3.57Å; L81-Q86 WeakPolarHBondContact O-CA 3.36Å; L81-Q86 WeakPolarHBondContact O-CB 3.48Å; L81-Q86 PolarHBondContact O-N 3.18Å; T84-Q86 WeakPolarHBondContact O-CG 3.41Å; T84-Q86 PolarHBondContact O-N 2.9Å; T84-Q86 PolarHBondContact OG1-NE2 2.94Å; Q86-H88 PolarHBondContact O-N 2.94Å; Q86-H88 VanDerWaalsContact O-N 3.07Å; Q86-L89 HydrophobicContact CB-CD1 4.36Å; Q86-L89 WeakPolarHBondContact O-CB 3.42Å; Q86-L89 PolarHBondContact O-N 3.21Å; Q86-Y90 PolarHBondContact O-N 3.05Å
87Q86.4Confident83.5Confident79 Ų7956.7 Ų56.737%0.36930%0.296SS..Hα-helixtrans-50.3-36.6-176.9-179.764.53800113.2L81 E85 L89 Y90 D91L81-Q87 PolarHBondContact O-N 2.84Å; E85-Q87 PolarHBondContact O-N 3.34Å; Q87-L89 VanDerWaalsContact C-N 3.25Å; Q87-L89 PolarHBondContact O-N 3.22Å; Q87-Y90 WeakPolarHBondContact O-CB 3.38Å; Q87-Y90 PolarHBondContact O-N 2.87Å; Q87-Y90 VanDerWaalsContact O-N 3.14Å; Q87-D91 PolarHBondContact NE2-OD2 2.74Å; Q87-D91 PolarHBondContact O-N 3.16Å
88H87Confident81.3Confident104 Ų10464.9 Ų64.948%0.48133%0.334SS..Hα-helixtrans-60.7-29.817871.2-79.7000113.9Q86 L92Q86-H88 PolarHBondContact O-N 2.94Å; Q86-H88 VanDerWaalsContact O-N 3.07Å; H88-L92 WeakPolarHBondContact O-CB 3.46Å; H88-L92 PolarHBondContact O-N 2.98Å; H88-L92 VanDerWaalsContact O-N 3.17Å
89L88.8Confident78.6Confident0 Ų076.2 Ų76.20%038%0.375CS..Hα-helixtrans-80.5-37.2175.1-57.6-178.1000111.6L21 Q24 L25 L81 Q86 Q87 L92 I93L21-L89 HydrophobicContact CD2-CB 3.97Å; L21-L89 HydrophobicContact CD2-CD1 4.18Å; L21-L89 HydrophobicContact CD2-CD2 4.14Å; L21-L89 HydrophobicContact CD2-CG 4.32Å; Q24-L89 HydrophobicContact CB-CD2 3.9Å; L25-L89 HydrophobicContact CB-CD1 4.04Å; L25-L89 HydrophobicContact CD1-CD1 3.83Å; L81-L89 HydrophobicContact CD1-CB 4.27Å; L81-L89 HydrophobicContact CD2-CB 4.2Å; L81-L89 HydrophobicContact CD2-CD1 4.26Å; Q86-L89 HydrophobicContact CB-CD1 4.36Å; Q86-L89 WeakPolarHBondContact O-CB 3.42Å; Q86-L89 PolarHBondContact O-N 3.21Å; Q87-L89 VanDerWaalsContact C-N 3.25Å; Q87-L89 PolarHBondContact O-N 3.22Å; L89-L92 PolarHBondContact O-N 3.2Å; L89-I93 WeakPolarHBondContact O-CD1 3.4Å; L89-I93 VanDerWaalsContact O-CG1 3.25Å; L89-I93 WeakPolarHBondContact O-CG1 3.47Å; L89-I93 PolarHBondContact O-N 3.08Å; L89-I93 VanDerWaalsContact O-N 3.08Å
90Y87.8Confident76Confident57 Ų5780.5 Ų80.522%0.22439%0.394CS..Hα-helixtrans-58.7-47.9170.9167.5-93000110.7C78 K82 Q86 Q87 L92 I93 A94C78-Y90 HydrophobicContact CB-CD2 3.72Å; C78-Y90 HydrophobicContact CB-CE2 3.84Å; K82-Y90 VanDerWaalsContact CE-CD2 3.43Å; K82-Y90 VanDerWaalsContact CE-CE1 3.47Å; K82-Y90 HydrophobicContact CG-CG 4.41Å; K82-Y90 PolarHBondContact NZ-OH 3.43Å; Q86-Y90 PolarHBondContact O-N 3.05Å; Q87-Y90 WeakPolarHBondContact O-CB 3.38Å; Q87-Y90 PolarHBondContact O-N 2.87Å; Q87-Y90 VanDerWaalsContact O-N 3.14Å; Y90-L92 PolarHBondContact O-N 3.17Å; Y90-I93 PolarHBondContact O-N 2.84Å; Y90-A94 HydrophobicContact CE1-CB 4.1Å; Y90-A94 HydrophobicContact CE2-CB 4.2Å; Y90-A94 VanDerWaalsContact O-CB 3.27Å; Y90-A94 WeakPolarHBondContact O-CB 3.4Å; Y90-A94 PolarHBondContact O-N 3.1Å
91D84.4Confident73.2Confident49 Ų4985.9 Ų85.926%0.26243%0.432SS..Hα-helixtrans-64-40.6179-80.7-54000112.3Q87 I93 A94 Q95Q87-D91 PolarHBondContact NE2-OD2 2.74Å; Q87-D91 PolarHBondContact O-N 3.16Å; D91-I93 VanDerWaalsContact C-N 3.27Å; D91-I93 PolarHBondContact O-N 3.09Å; D91-A94 PolarHBondContact O-N 3.14Å; D91-Q95 HydrophobicContact CB-CG 4.48Å; D91-Q95 VanDerWaalsContact CG-NE2 3.32Å; D91-Q95 WeakPolarHBondContact O-CB 3.47Å; D91-Q95 VanDerWaalsContact O-CG 3.25Å; D91-Q95 WeakPolarHBondContact O-CG 3.36Å; D91-Q95 PolarHBondContact O-N 3.4Å; D91-Q95 PolarHBondContact OD1-NE2 3.07Å
92L86.4Confident70.3Confident68 Ų6897.7 Ų97.736%0.35648%0.476SS..Hα-helixtrans-59.9-35.2173.9-179.666.2000113.1N17 V20 H88 L89 Y90N17-L92 HydrophobicContact CB-CD2 4.35Å; N17-L92 HydrophobicContact CB-CG 4.47Å; N17-L92 PolarHBondContact ND2-O 3.4Å; V20-L92 HydrophobicContact CB-CD2 3.87Å; V20-L92 HydrophobicContact CG1-CD2 3.6Å; V20-L92 HydrophobicContact CG2-CD2 4.29Å; H88-L92 WeakPolarHBondContact O-CB 3.46Å; H88-L92 PolarHBondContact O-N 2.98Å; H88-L92 VanDerWaalsContact O-N 3.17Å; L89-L92 PolarHBondContact O-N 3.2Å; Y90-L92 PolarHBondContact O-N 3.17Å
93I86.5Confident67.8Low4 Ų4102.3 Ų102.32%0.02150%0.499CS..Hα-helixtrans-79.5-45.2177.9-66.8165.9000111.3A13 L14 N17 L21 F74 F77 L81 L89 Y90 D91A13-I93 HydrophobicContact CB-CG2 4.25Å; L14-I93 HydrophobicContact CD2-CD1 3.99Å; N17-I93 WeakPolarHBondContact ND2-CA 3.34Å; L21-I93 HydrophobicContact CD1-CD1 4Å; L21-I93 HydrophobicContact CD1-CG1 4.29Å; L21-I93 HydrophobicContact CD2-CD1 3.88Å; L21-I93 HydrophobicContact CD2-CG1 4.4Å; F74-I93 HydrophobicContact CE2-CG2 3.55Å; F74-I93 HydrophobicContact CZ-CG2 3.41Å; F74-I93 VanDerWaalsContact CZ-CG2 3.41Å; F77-I93 HydrophobicContact CE1-CD1 4.03Å; L81-I93 HydrophobicContact CD1-CD1 3.98Å; L89-I93 WeakPolarHBondContact O-CD1 3.4Å; L89-I93 VanDerWaalsContact O-CG1 3.25Å; L89-I93 WeakPolarHBondContact O-CG1 3.47Å; L89-I93 PolarHBondContact O-N 3.08Å; L89-I93 VanDerWaalsContact O-N 3.08Å; Y90-I93 PolarHBondContact O-N 2.84Å; D91-I93 VanDerWaalsContact C-N 3.27Å; D91-I93 PolarHBondContact O-N 3.09Å
94A77.4Confident64.9Low51 Ų51102.4 Ų102.442%0.42151%0.509SS..Hα-helixtrans-78.4-34.7-172.700000113.3Y90 D91 S96Y90-A94 HydrophobicContact CE1-CB 4.1Å; Y90-A94 HydrophobicContact CE2-CB 4.2Å; Y90-A94 VanDerWaalsContact O-CB 3.27Å; Y90-A94 WeakPolarHBondContact O-CB 3.4Å; Y90-A94 PolarHBondContact O-N 3.1Å; D91-A94 PolarHBondContact O-N 3.14Å; A94-S96 PolarHBondContact O-N 3.04Å; A94-S96 VanDerWaalsContact O-N 3.1Å
95Q67.4Low61.9Low139 Ų139109 Ų10965%0.6554%0.538SS*.THydrogen-bonded Turntrans-84.431.1-175.3-57.7-175.524.200113.7D91 P97D91-Q95 HydrophobicContact CB-CG 4.48Å; D91-Q95 VanDerWaalsContact CG-NE2 3.32Å; D91-Q95 WeakPolarHBondContact O-CB 3.47Å; D91-Q95 VanDerWaalsContact O-CG 3.25Å; D91-Q95 WeakPolarHBondContact O-CG 3.36Å; D91-Q95 PolarHBondContact O-N 3.4Å; D91-Q95 PolarHBondContact OD1-NE2 3.07Å; Q95-P97 WeakPolarHBondContact O-CD 3.42Å
96S56Low59.1Low46 Ų46107 Ų10732%0.32254%0.537SS..  trans-112.157.1177.380.80000115.3A94A94-S96 PolarHBondContact O-N 3.04Å; A94-S96 VanDerWaalsContact O-N 3.1Å
97P47.3Very low56Low107 Ų107112 Ų11270%0.69556%0.564SS**  trans-68167.2165.633.7-34.8000111Q95 R99Q95-P97 WeakPolarHBondContact O-CD 3.42Å; P97-R99 PolarHBondContact O-N 2.94Å
98E46.9Very low53.2Low173 Ų173113.7 Ų113.781%0.80858%0.584SS**  trans-70.7122.5-171.5-56.7-170.8139.700112.9
99R33.3Very low50.4Low250 Ų250116.2 Ų116.294%0.94360%0.599SS**  trans-110.981.7159.4-97.8-171.3171.2-175.2-0.8109.9P97P97-R99 PolarHBondContact O-N 2.94Å
100N34.3Very low47.5Very low135 Ų135124.8 Ų124.872%0.72264%0.639SS**  trans-74.9161.3154.4-89.8-24.7000109.9
101S32.9Very low44.4Very low113 Ų113126.8 Ų126.879%0.7967%0.667SS**  trans59.992.6160.2-53.20000117.7
102R28.5Very low41.5Very low248 Ų248131.9 Ų131.994%0.93669%0.69SS**  -163.6132.9124.9-106.8159-159.3-159.62.6112.2
103E35.2Very low38.4Very low188 Ų188135.9 Ų135.988%0.87970%0.704SS**  trans-73143.7162.4-57.6142.4124.700109.1
104T27.7Very low35.4Very low128 Ų128141.6 Ų141.679%0.78574%0.739SS**  trans-142.499155.842.30000109.3
105H26.9Very low33Very low159 Ų159145.2 Ų145.274%0.73676%0.758SS**  trans-61.2136157.3-139.1-95000108.4D107H105-D107 IonicContact CE1-OD1 3.42Å; H105-D107 PolarHBondContact CE1-OD1 2.91Å; H105-D107 VanDerWaalsContact CE1-OD1 3.29Å; H105-D107 IonicContact CE1-OD2 3.16Å; H105-D107 PolarHBondContact CE1-OD2 3.24Å; H105-D107 IonicContact CG-OD2 3.64Å; H105-D107 IonicContact ND1-OD1 2.75Å; H105-D107 PolarHBondContact ND1-OD1 3Å; H105-D107 IonicContact ND1-OD2 3.24Å; H105-D107 PolarHBondContact ND1-OD2 2.77Å
106V29.1Very low30.9Very low135 Ų135147.3 Ų147.382%0.81877%0.768SS**  trans-142.8117.8164.2-175.40000107.6
107D26.6Very low29.3Very low118 Ų118152.4 Ų152.463%0.63179%0.787SS**  trans-92.1173.2-170.7-70.4-82.6000114.6H105H105-D107 IonicContact CE1-OD1 3.42Å; H105-D107 PolarHBondContact CE1-OD1 2.91Å; H105-D107 VanDerWaalsContact CE1-OD1 3.29Å; H105-D107 IonicContact CE1-OD2 3.16Å; H105-D107 PolarHBondContact CE1-OD2 3.24Å; H105-D107 IonicContact CG-OD2 3.64Å; H105-D107 IonicContact ND1-OD1 2.75Å; H105-D107 PolarHBondContact ND1-OD1 3Å; H105-D107 IonicContact ND1-OD2 3.24Å; H105-D107 PolarHBondContact ND1-OD2 2.77Å
108C26.9Very low28.1Very low115 Ų115154.6 Ų154.678%0.77779%0.785SS**  trans-73.2156.2-166.3-45.60000116.3
109I28.5Very low27.1Very low157 Ų157149.8 Ų149.881%0.80577%0.771SS**  trans-133.794.9149.6-61.5-176.5000106.8
110Q26.4Very low26.6Very low181 Ų181146.3 Ų146.385%0.84677%0.765SS**  77.9153.8104.4-69.6-176.8-0.100116.1
111A24.3Very low26.2Very low98 Ų98151.5 Ų151.581%0.8178%0.775SS**  trans-153.4143.4-166.700000115.1
112E21.9Very low26.2Very low157 Ų157151.4 Ų151.473%0.73477%0.771SS**  trans-162.5157.8165-72.4-149.2157.100108.6
113K22.3Very low26Very low152 Ų152146.8 Ų146.866%0.66176%0.76SS**  cis-160.5143.4-12.3-114176.6-167141.40111.3
114V23.7Very low25.5Very low124 Ų124146 Ų14675%0.75275%0.754SS**  18.6126.8123.5-178.20000116.9
115P27.3Very low25.4Very low126 Ų126146.9 Ų146.982%0.81875%0.751SS**  -144.8169.475.339.4-21000119.4
116E22.2Very low25.2Very low183 Ų183149.8 Ų149.886%0.85576%0.755SS**  trans-103.7162.9-178.9-56.5175.7103.900113.9
117E22.8Very low25Very low154 Ų154147.7 Ų147.772%0.7275%0.747SS**  trans164.8159.3140.9-92-158.4164.900108.3
118K22.8Very low25Very low152 Ų152149.8 Ų149.866%0.66176%0.758SS**  cis-159178.7-3.2-124.5179.3-168133.20107.3
119S25.1Very low24.8Very low72 Ų72147.4 Ų147.450%0.50375%0.753SS.*  cis-155.3152.51.9-147.70000112.6
120Q24.3Very low24.7Very low178 Ų178148.3 Ų148.383%0.83275%0.754SS**  trans45.6134.1135.8-67.8167.7-14.500124.6
121R24.5Very low24.7Very low244 Ų244149.4 Ų149.492%0.92175%0.75SS**  trans-89.4174.1160.4-98.7179.1-177.3-179.41.9109.8
122P32.8Very low24.7Very low110 Ų110151.1 Ų151.171%0.71475%0.751SS**  -160.1176.25643.6-19.9000121
123E24.2Very low25Very low151 Ų151149 Ų14971%0.70675%0.754SS**  trans34.3157.3140.5-64.1-169.8134.200123.3
124K26.1Very low25.1Very low172 Ų172149.1 Ų149.175%0.74876%0.761SS**  cis168.7154.3-17-98.6175.4-174.8158.80106.1
125M23.8Very low25.8Very low146 Ų146148.9 Ų148.972%0.71976%0.762SS**  trans113.7117.2133.4-158.9163.370.400122
126R23.8Very low25.9Very low221 Ų221151.4 Ų151.483%0.83476%0.76SS**  trans63.1159.8151.7-74172.5-173.9178.80.5118.7
127S25.1Very low26.4Very low91 Ų91148 Ų14864%0.63675%0.753SS**  cis-164.8-174.4-20.355.50000110.9
128N25.9Very low26.6Very low161 Ų161146.8 Ų146.886%0.86176%0.757SS**  trans82.8154.1175-45.81.9000114.6
129G23.7Very low26.8Very low66 Ų66147.5 Ų147.568%0.6876%0.763SS**  cis158.5143.6-10.400000113.1
130E25.8Very low26.8Very low176 Ų176151.8 Ų151.882%0.82278%0.775SS**  trans67.2160.2170.6-56.4-160.5110.600118.3
131R27Very low26.8Very low203 Ų203151 Ų15177%0.76677%0.771SS**  cis-165.1158.8-35-110.9-178.2167.8-166.6-2.6109.8
132T24.5Very low26.8Very low135 Ų135149.6 Ų149.683%0.82877%0.767SS**  trans62.6155.2158.739.70000118.9
133S26.6Very low26.3Very low113 Ų113149 Ų14979%0.7977%0.772SS**  cis-159.9167.8-8.442.10000112.7
134L25.9Very low26.6Very low154 Ų154146.2 Ų146.281%0.80678%0.775SS**  trans-73.9-179.5172.8-70.4170.9000112.7
135P37.4Very low26.7Very low119 Ų119148.4 Ų148.477%0.77378%0.784SS**  cis-145.5-174.418.344.6-23.7000119.6
136F29.7Very low26.8Very low178 Ų178153.1 Ų153.178%0.78179%0.794SS**  trans-69.7169.1165-75.6-96.5000113.3
137P32.6Very low27Very low111 Ų111147.2 Ų147.272%0.72179%0.792SS**  -125.9-174.587.842.5-35.6000111.5
138T26.4Very low27.1Very low130 Ų130155 Ų15580%0.79881%0.808SS**  cis-146.5-159.85.4-26.10000109.8
139Q26.9Very low27.4Very low167 Ų167153.3 Ų153.378%0.7880%0.804SS**  trans-134.2164.7169.4-63.8165.8-101.300110.4
140E25.5Very low27.4Very low161 Ų161158.4 Ų158.475%0.75281%0.809SS**  -161.1157.2124.6-121.5177.5-140.900112.2Y142E140-Y142 PolarHBondContact OE2-OH 3.02Å
141E23.6Very low27.6Very low163 Ų163155.4 Ų155.476%0.76280%0.803SS**  trans-119.5147-176.1-60.1177.9104.300111.7
142Y24.6Very low27.7Very low213 Ų213154.9 Ų154.984%0.83581%0.809SS**  trans-144.3154.2156.5-71.6-69.9000111.9E140E140-Y142 PolarHBondContact OE2-OH 3.02Å
143A23.7Very low28Very low98 Ų98153.2 Ų153.281%0.8180%0.803SS**  trans-118.7145.7-15600000117
144A30.7Very low28.3Very low93 Ų93156.6 Ų156.677%0.76981%0.809SS**  trans33.4130147.700000122.2
145K27.1Very low28.5Very low218 Ų218158.3 Ų158.395%0.94881%0.812SS**  trans-158.4158.8141.6-109.2144.3-168.5169.20114.8
146R25.8Very low28.1Very low245 Ų245160.8 Ų160.893%0.92581%0.812SS**  trans-58.2150.5-167-86.5174.6163.6157.9-7.1117.1
147A28Very low28.1Very low96 Ų96157 Ų15779%0.79381%0.807SS**  trans-44.7156.9166.600000118
148R27.1Very low28Very low254 Ų254159.3 Ų159.396%0.95881%0.813SS**  trans-149.8154.1144.5-111.4174.4-174.3170.21.5110.9
149T31.9Very low28.4Very low127 Ų127159.6 Ų159.678%0.77981%0.809SS**  trans-86.6134.6-177.247.80000112.6
150H25.6Very low29.2Very low172 Ų172154.8 Ų154.880%0.79680%0.798SS**  -168.7145.6128.6-119.8-79.7000113.2
151T29.7Very low30.3Very low113 Ų113151.7 Ų151.769%0.69379%0.786SS**  trans31.392.8157.6-43.10000117.9S153T151-S153 PolarHBondContact O-N 3.17Å; T151-S153 VanDerWaalsContact O-N 3.13Å
152E28.7Very low31.8Very low193 Ų193147.6 Ų147.690%0.90278%0.776SS**  trans-71101.6158.3-72.2-177.6156.300109.8M154E152-M154 PolarHBondContact O-N 3.15Å
153S30Very low33.8Very low99 Ų99139.3 Ų139.369%0.69275%0.748SS**  trans-69.6108.3158.249.80000108.2T151 E155T151-S153 PolarHBondContact O-N 3.17Å; T151-S153 VanDerWaalsContact O-N 3.13Å; S153-E155 PolarHBondContact O-N 3.5Å; S153-E155 VanDerWaalsContact O-N 3.08Å
154M33.2Very low36.2Very low185 Ų185138.4 Ų138.491%0.91173%0.729SS**  trans-57.4114.2175.9-78.4-176.9163.500110.5E152 F156E152-M154 PolarHBondContact O-N 3.15Å; M154-F156 PolarHBondContact O-N 2.71Å
155E29.8Very low38.3Very low189 Ų189138.9 Ų138.988%0.88373%0.727SS**  trans-67.6115.2171.8-67-169.113800109.4S153 S157S153-E155 PolarHBondContact O-N 3.5Å; S153-E155 VanDerWaalsContact O-N 3.08Å; E155-S157 PolarHBondContact O-N 2.95Å
156F30Very low41.1Very low172 Ų172131.9 Ų131.975%0.75470%0.702SS**  trans-79.290.7-176.4-161.3-82.9000109.7M154M154-F156 PolarHBondContact O-N 2.71Å
157S28.6Very low44Very low97 Ų97124.1 Ų124.168%0.67868%0.683SS**  trans-58.1139.6177.1-1690000111.3E155 D159E155-S157 PolarHBondContact O-N 2.95Å; S157-D159 VanDerWaalsContact C-N 3.27Å; S157-D159 PolarHBondContact O-N 3.48Å; S157-D159 VanDerWaalsContact O-N 3.09Å
158L32Very low47Very low161 Ų161119.6 Ų119.684%0.84365%0.646SS**SBendtrans-8112.2-158.8-71.3167.5000116.1A160L158-A160 PolarHBondContact O-N 3.16Å
159D35Very low50Low135 Ų135110.5 Ų110.572%0.72262%0.616SS**  trans-83.256174.7-76.2-39.5000112.6S157 D161 S162S157-D159 VanDerWaalsContact C-N 3.27Å; S157-D159 PolarHBondContact O-N 3.48Å; S157-D159 VanDerWaalsContact O-N 3.09Å; D159-D161 PolarHBondContact O-N 2.94Å; D159-S162 PolarHBondContact O-N 2.91Å
160A43.6Very low52.8Low67 Ų67108.2 Ų108.255%0.55460%0.604SS**THydrogen-bonded Turntrans-64.8-9.4-174.300000115.5L158L158-A160 PolarHBondContact O-N 3.16Å
161D47.4Very low55.9Low95 Ų95100.5 Ų100.551%0.50857%0.569SS.*THydrogen-bonded Turntrans-80.7-16-177.5-106.55.7000113.5D159 K388 R389D159-D161 PolarHBondContact O-N 2.94Å; D161-K388 IonicContact OD2-NZ 3.87Å; D161-K388 PolarHBondContact OD2-NZ 2.76Å; D161-R389 WeakPolarHBondContact O-CG 3.46Å
162S56.4Low58.9Low78 Ų7897.6 Ų97.655%0.54556%0.556SS.*SBendtrans-80.1149.8-175.6-71.80000114.4D159D159-S162 PolarHBondContact O-N 2.91Å
163P66.1Low61.8Low38 Ų3891.8 Ų91.825%0.24754%0.535CS..PPolyproline II helixtrans-61.7145.5166.1-19.731.8000112S165 V218 V222P163-S165 PolarHBondContact O-N 3Å; P163-S165 VanDerWaalsContact O-N 3.13Å; P163-V218 HydrophobicContact CG-CG1 3.55Å; P163-V222 HydrophobicContact CB-CG2 3.78Å; P163-V222 HydrophobicContact CG-CG2 4.14Å
164I73.7Confident64.7Low80 Ų8093.1 Ų93.141%0.4153%0.534SS..PPolyproline II helixtrans-61.2117.8-177.4-68.4177.4000110.9T166 N398 T399 R402I164-T166 HydrophobicContact CG2-CG2 4.49Å; I164-T166 WeakPolarHBondContact CG2-OG1 3.48Å; I164-N398 PolarHBondContact O-ND2 3.05Å; I164-N398 VanDerWaalsContact O-ND2 3.1Å; I164-T399 HydrophobicContact CD1-CG2 3.71Å; I164-R402 PolarHBondContact O-NE 2.93Å
165S73.8Confident67.5Low102 Ų10286.2 Ų86.271%0.71350%0.499SS*.  trans-105.71.7-174.857.30000113.9P163P163-S165 PolarHBondContact O-N 3Å; P163-S165 VanDerWaalsContact O-N 3.13Å
166T85.7Confident70.4Confident72 Ų7278.1 Ų78.144%0.44246%0.461SS..PPolyproline II helixtrans-59.6134.317949.70000110.6I164 R402I164-T166 HydrophobicContact CG2-CG2 4.49Å; I164-T166 WeakPolarHBondContact CG2-OG1 3.48Å; T166-R402 VanDerWaalsContact O-CD 3.29Å; T166-R402 WeakPolarHBondContact O-CD 3.4Å; T166-R402 PolarHBondContact O-NH1 2.76Å
167P88.3Confident73.3Confident81 Ų8174.7 Ų74.753%0.52645%0.45SS..PPolyproline II helixtrans-65.3142.9-172.126.5-35000111.4L169 E229P167-L169 PolarHBondContact O-N 3.42Å; P167-L169 VanDerWaalsContact O-N 3.17Å; P167-E229 VanDerWaalsContact CA-OE2 3.3Å; P167-E229 WeakPolarHBondContact CA-OE2 3.48Å
168V91.3Very high76.3Confident2 Ų273.4 Ų73.41%0.01244%0.441CS..PPolyproline II helixtrans-53.4123.3176177.50000109.6V226 E229 L230 R402 P454 K455V168-V226 HydrophobicContact CG2-CG2 3.88Å; V168-E229 HydrophobicContact CB-CB 4.05Å; V168-E229 HydrophobicContact CG2-CB 3.58Å; V168-E229 HydrophobicContact CG2-CG 4.48Å; V168-E229 PolarHBondContact N-OE2 2.84Å; V168-L230 HydrophobicContact CG1-CD2 3.88Å; V168-L230 HydrophobicContact CG1-CG 4.4Å; V168-L230 HydrophobicContact CG2-CG 4.49Å; V168-R402 HydrophobicContact CG2-CG 3.89Å; V168-P454 HydrophobicContact CG1-CB 3.71Å; V168-P454 HydrophobicContact CG1-CG 4.21Å; V168-K455 WeakPolarHBondContact O-CE 3.49Å; V168-K455 PolarHBondContact O-NZ 2.91Å
169L89.1Confident79.1Confident63 Ų6368.3 Ų68.333%0.3341%0.413SS..PPolyproline II helixtrans-68.3142.9-177.1-60.6-179000111.1P167 R402 R406 P454P167-L169 PolarHBondContact O-N 3.42Å; P167-L169 VanDerWaalsContact O-N 3.17Å; L169-R402 PolarHBondContact N-O 3.33Å; L169-R402 VanDerWaalsContact N-O 3.12Å; L169-R406 HydrophobicContact CB-CG 4.28Å; L169-P454 WeakPolarHBondContact O-CB 3.48Å; L169-P454 WeakPolarHBondContact O-CG 3.49Å
170P90.2Very high81.6Confident79 Ų7963.4 Ų63.451%0.51339%0.388SS..PPolyproline II helixtrans-73.4150.5178.731.2-35.4000112.2R406 P454 K455P170-R406 WeakPolarHBondContact O-CB 3.43Å; P170-P454 CarbonylContact C-O 3.51Å; P170-P454 WeakPolarHBondContact CA-O 3.47Å; P170-K455 HydrophobicContact CB-CB 4.11Å; P170-K455 HydrophobicContact CB-CD 4.45Å
171C91.9Very high83.7Confident10 Ų1068.6 Ų68.67%0.06840%0.399CS..PPolyproline II helixtrans-71.5135169.7-179.30000110.7F453 P454C171-F453 HydrophobicContact CB-CB 4.48Å; C171-P454 HydrophobicContact CB-CG 4.39Å; C171-P454 PolarHBondContact N-O 3.11Å
172A91.1Very high85.6Confident51 Ų5171.1 Ų71.142%0.42141%0.407SS..PPolyproline II helixtrans-71141.5171.600000110.7D174 F175 Y176A172-D174 VanDerWaalsContact C-N 3.33Å; A172-D174 PolarHBondContact O-N 2.86Å; A172-F175 HydrophobicContact CB-CB 4.13Å; A172-F175 WeakPolarHBondContact O-CB 3.39Å; A172-F175 PolarHBondContact O-N 2.74Å; A172-Y176 PolarHBondContact O-N 3.01Å; A172-Y176 VanDerWaalsContact O-N 3.09Å
173P89.7Confident87.4Confident72 Ų7267.6 Ų67.647%0.46838%0.382SS..Hα-helixtrans-57-42.9177.1-27.636.3000113.4F175 Y176 L177 Y456P173-F175 VanDerWaalsContact C-N 3.29Å; P173-F175 PolarHBondContact O-N 2.88Å; P173-Y176 PolarHBondContact O-N 2.87Å; P173-L177 WeakPolarHBondContact O-CB 3.34Å; P173-L177 VanDerWaalsContact O-CG 3.3Å; P173-L177 WeakPolarHBondContact O-CG 3.41Å; P173-L177 PolarHBondContact O-N 3.21Å; P173-Y456 HydrophobicContact CB-CE2 4.09Å; P173-Y456 HydrophobicContact CG-CE2 4.42Å
174D91.1Very high88.7Confident126 Ų12666.2 Ų66.267%0.67437%0.372SS*.Hα-helixtrans-65.9-33.9-179.1-53.2-42.4000112.1A172 S178A172-D174 VanDerWaalsContact C-N 3.33Å; A172-D174 PolarHBondContact O-N 2.86Å; D174-S178 WeakPolarHBondContact O-CB 3.24Å; D174-S178 PolarHBondContact O-N 3.47Å; D174-S178 VanDerWaalsContact O-N 3.11Å; D174-S178 PolarHBondContact O-OG 2.88Å
175F92.5Very high89.6Confident40 Ų4070.1 Ų70.118%0.17538%0.382CS..Hα-helixtrans-67-45.2174.3-172.6-88000111.3A172 P173 S178 H179 R406 D407 Y451 F453A172-F175 HydrophobicContact CB-CB 4.13Å; A172-F175 WeakPolarHBondContact O-CB 3.39Å; A172-F175 PolarHBondContact O-N 2.74Å; P173-F175 VanDerWaalsContact C-N 3.29Å; P173-F175 PolarHBondContact O-N 2.88Å; F175-S178 WeakPolarHBondContact CA-OG 3.45Å; F175-S178 PolarHBondContact O-N 3.29Å; F175-S178 PolarHBondContact O-OG 3.4Å; F175-H179 AromaticContact CD2-CE1 3.62Å; F175-H179 AromaticContact CD2-ND1 3.72Å; F175-H179 HydrophobicContact CE1-CB 4.4Å; F175-H179 AromaticContact CE1-ND1 3.8Å; F175-H179 AromaticContact CE2-CE1 3.21Å; F175-H179 WeakPolarHBondContact CE2-CE1 3.45Å; F175-H179 AromaticContact CE2-ND1 3.49Å; F175-H179 WeakPolarHBondContact CE2-ND1 3.5Å; F175-H179 AromaticContact CE2-NE2 3.77Å; F175-H179 AromaticContact CG-ND1 3.96Å; F175-H179 AromaticContact CZ-CD2 4Å; F175-H179 AromaticContact CZ-CE1 3.58Å; F175-H179 AromaticContact CZ-CG 3.78Å; F175-H179 AromaticContact CZ-ND1 3.5Å; F175-H179 AromaticContact CZ-NE2 3.89Å; F175-H179 PolarHBondContact O-N 3.25Å; F175-H179 PolarHBondContact O-ND1 2.92Å; F175-R406 WeakPolarHBondContact CD1-O 3.4Å; F175-D407 HydrophobicContact CD2-CB 4.4Å; F175-D407 HydrophobicContact CE2-CB 4.23Å; F175-D407 WeakPolarHBondContact CE2-O 3.35Å; F175-D407 VanDerWaalsContact CZ-C 3.5Å; F175-D407 HydrophobicContact CZ-CB 4.46Å; F175-D407 WeakPolarHBondContact CZ-O 3.2Å; F175-Y451 AromaticContact CE1-CD1 3.72Å; F175-Y451 HydrophobicContact CE1-CD1 3.72Å; F175-Y451 AromaticContact CE1-CE1 3.86Å; F175-Y451 HydrophobicContact CE1-CE1 3.86Å; F175-Y451 HydrophobicContact CE1-CG 4.3Å; F175-Y451 AromaticContact CZ-CD1 3.87Å; F175-Y451 HydrophobicContact CZ-CD1 3.87Å; F175-Y451 AromaticContact CZ-CE1 3.51Å; F175-Y451 HydrophobicContact CZ-CE1 3.51Å; F175-F453 HydrophobicContact CD1-CE1 4.16Å; F175-F453 HydrophobicContact CE1-CE1 4.06Å
176Y90.7Very high90.4Very high20 Ų2065.5 Ų65.58%0.07835%0.349CS..Hα-helixtrans-59.3-49.9173.4175.1-90.8000111.3A172 P173 S178 H179 C180 F453 Y456A172-Y176 PolarHBondContact O-N 3.01Å; A172-Y176 VanDerWaalsContact O-N 3.09Å; P173-Y176 PolarHBondContact O-N 2.87Å; Y176-S178 VanDerWaalsContact C-N 3.26Å; Y176-S178 PolarHBondContact O-N 3.31Å; Y176-H179 PolarHBondContact O-N 3.26Å; Y176-C180 HydrophobicContact CD1-CB 4.2Å; Y176-C180 HydrophobicContact CD2-CB 3.97Å; Y176-C180 HydrophobicContact CE1-CB 3.89Å; Y176-C180 VanDerWaalsContact CE1-SG 3.59Å; Y176-C180 HydrophobicContact CE2-CB 3.65Å; Y176-C180 HydrophobicContact CG-CB 4.24Å; Y176-C180 WeakPolarHBondContact O-CB 3.37Å; Y176-C180 PolarHBondContact O-N 3.45Å; Y176-C180 PolarHBondContact O-SG 3.4Å; Y176-F453 HydrophobicContact CD2-CB 4.15Å; Y176-F453 AromaticContact CD2-CD1 3.87Å; Y176-F453 HydrophobicContact CD2-CD1 3.87Å; Y176-F453 AromaticContact CD2-CD2 3.65Å; Y176-F453 HydrophobicContact CD2-CD2 3.65Å; Y176-F453 HydrophobicContact CD2-CE1 4.1Å; Y176-F453 AromaticContact CD2-CE2 3.9Å; Y176-F453 HydrophobicContact CD2-CE2 3.9Å; Y176-F453 AromaticContact CD2-CG 3.64Å; Y176-F453 HydrophobicContact CD2-CG 3.64Å; Y176-F453 HydrophobicContact CD2-CZ 4.11Å; Y176-F453 AromaticContact CE2-CD2 3.78Å; Y176-F453 HydrophobicContact CE2-CD2 3.78Å; Y176-F453 HydrophobicContact CE2-CE2 4.01Å; Y176-F453 HydrophobicContact CE2-CG 4.2Å; Y176-Y456 HydrophobicContact CD1-CD1 4Å; Y176-Y456 AromaticContact CD1-CE1 3.26Å; Y176-Y456 HydrophobicContact CD1-CE1 3.26Å; Y176-Y456 HydrophobicContact CD1-CE2 4.22Å; Y176-Y456 AromaticContact CD1-CZ 3.38Å; Y176-Y456 WeakPolarHBondContact CD1-OH 3.3Å; Y176-Y456 AromaticContact CD2-CD1 3.63Å; Y176-Y456 HydrophobicContact CD2-CD1 3.63Å; Y176-Y456 AromaticContact CD2-CE1 3.74Å; Y176-Y456 HydrophobicContact CD2-CE1 3.74Å; Y176-Y456 HydrophobicContact CD2-CG 4.3Å; Y176-Y456 HydrophobicContact CE1-CD1 4.23Å; Y176-Y456 AromaticContact CE1-CE1 3.36Å; Y176-Y456 HydrophobicContact CE1-CE1 3.36Å; Y176-Y456 AromaticContact CE1-CZ 3.82Å; Y176-Y456 AromaticContact CE2-CD1 3.87Å; Y176-Y456 HydrophobicContact CE2-CD1 3.87Å; Y176-Y456 AromaticContact CE2-CE1 3.83Å; Y176-Y456 HydrophobicContact CE2-CE1 3.83Å; Y176-Y456 AromaticContact CG-CD1 3.7Å; Y176-Y456 HydrophobicContact CG-CD1 3.7Å; Y176-Y456 HydrophobicContact CG-CD2 4.47Å; Y176-Y456 AromaticContact CG-CE1 3.46Å; Y176-Y456 HydrophobicContact CG-CE1 3.46Å; Y176-Y456 VanDerWaalsContact CG-CE1 3.46Å; Y176-Y456 HydrophobicContact CG-CE2 4.28Å; Y176-Y456 HydrophobicContact CG-CG 4.2Å; Y176-Y456 AromaticContact CG-CZ 3.78Å; Y176-Y456 AromaticContact CZ-CE1 3.65Å
177L90.4Very high90.6Very high99 Ų9963.9 Ų63.952%0.51834%0.338SS..Hα-helixtrans-63.5-28.9-175.4-71.8171.7000113.7P173P173-L177 WeakPolarHBondContact O-CB 3.34Å; P173-L177 VanDerWaalsContact O-CG 3.3Å; P173-L177 WeakPolarHBondContact O-CG 3.41Å; P173-L177 PolarHBondContact O-N 3.21Å
178S91.6Very high90.8Very high70 Ų7060.9 Ų60.949%0.4932%0.319SS..Hα-helixtrans-77.8-41.7174.941.60000113D174 F175 Y176D174-S178 WeakPolarHBondContact O-CB 3.24Å; D174-S178 PolarHBondContact O-N 3.47Å; D174-S178 VanDerWaalsContact O-N 3.11Å; D174-S178 PolarHBondContact O-OG 2.88Å; F175-S178 WeakPolarHBondContact CA-OG 3.45Å; F175-S178 PolarHBondContact O-N 3.29Å; F175-S178 PolarHBondContact O-OG 3.4Å; Y176-S178 VanDerWaalsContact C-N 3.26Å; Y176-S178 PolarHBondContact O-N 3.31Å
179H91.8Very high90.8Very high55 Ų5564.2 Ų64.226%0.25534%0.342SS..Hα-helixtrans-96.7-28.9-170.3-61.579.9000114.9F175 Y176 K181 Q182 S183 Y451 F453F175-H179 AromaticContact CD2-CE1 3.62Å; F175-H179 AromaticContact CD2-ND1 3.72Å; F175-H179 HydrophobicContact CE1-CB 4.4Å; F175-H179 AromaticContact CE1-ND1 3.8Å; F175-H179 AromaticContact CE2-CE1 3.21Å; F175-H179 WeakPolarHBondContact CE2-CE1 3.45Å; F175-H179 AromaticContact CE2-ND1 3.49Å; F175-H179 WeakPolarHBondContact CE2-ND1 3.5Å; F175-H179 AromaticContact CE2-NE2 3.77Å; F175-H179 AromaticContact CG-ND1 3.96Å; F175-H179 AromaticContact CZ-CD2 4Å; F175-H179 AromaticContact CZ-CE1 3.58Å; F175-H179 AromaticContact CZ-CG 3.78Å; F175-H179 AromaticContact CZ-ND1 3.5Å; F175-H179 AromaticContact CZ-NE2 3.89Å; F175-H179 PolarHBondContact O-N 3.25Å; F175-H179 PolarHBondContact O-ND1 2.92Å; Y176-H179 PolarHBondContact O-N 3.26Å; H179-K181 PolarHBondContact O-N 2.91Å; H179-Q182 PolarHBondContact O-N 2.84Å; H179-S183 PolarHBondContact O-N 3.39Å; H179-S183 VanDerWaalsContact O-N 3.17Å; H179-S183 PolarHBondContact O-OG 2.85Å; H179-Y451 HydrophobicContact CB-CD2 4.2Å; H179-Y451 HydrophobicContact CB-CE2 3.95Å; H179-Y451 AromaticContact CD2-CE2 3.98Å; H179-Y451 AromaticContact CD2-CZ 3.74Å; H179-Y451 PolarHBondContact CD2-OH 2.88Å; H179-F453 HydrophobicContact CB-CE1 4.48Å; H179-F453 HydrophobicContact CB-CZ 4.32Å
180C87.2Confident91.1Very high31 Ų3163.4 Ų63.421%0.20934%0.341CS..THydrogen-bonded Turntrans-61.9-14.2-169.566.80000116.1Y176 S183 F453Y176-C180 HydrophobicContact CD1-CB 4.2Å; Y176-C180 HydrophobicContact CD2-CB 3.97Å; Y176-C180 HydrophobicContact CE1-CB 3.89Å; Y176-C180 VanDerWaalsContact CE1-SG 3.59Å; Y176-C180 HydrophobicContact CE2-CB 3.65Å; Y176-C180 HydrophobicContact CG-CB 4.24Å; Y176-C180 WeakPolarHBondContact O-CB 3.37Å; Y176-C180 PolarHBondContact O-N 3.45Å; Y176-C180 PolarHBondContact O-SG 3.4Å; C180-S183 WeakPolarHBondContact CA-OG 3.38Å; C180-F453 HydrophobicContact CB-CE2 4.21Å; C180-F453 HydrophobicContact CB-CZ 4.22Å
181K87.3Confident91.2Very high177 Ų17760.1 Ų60.177%0.7732%0.318SS*.THydrogen-bonded Turntrans-85.2-24.1177.8-66176.6-176.5168.90113.4H179H179-K181 PolarHBondContact O-N 2.91Å
182Q87.6Confident91.4Very high148 Ų14859.7 Ų59.769%0.69232%0.315SS*.THydrogen-bonded Turntrans-105.1-29.6-175.8-65-178.9-4.500111.6H179H179-Q182 PolarHBondContact O-N 2.84Å
183S93.5Very high91.8Very high3 Ų357.9 Ų57.92%0.02130%0.298CS..SBendtrans-70.4179.1174.569.50000114.2H179 C180 K448 D449H179-S183 PolarHBondContact O-N 3.39Å; H179-S183 VanDerWaalsContact O-N 3.17Å; H179-S183 PolarHBondContact O-OG 2.85Å; C180-S183 WeakPolarHBondContact CA-OG 3.38Å; S183-K448 WeakPolarHBondContact O-CD 3.44Å; S183-K448 PolarHBondContact O-NZ 3.38Å; S183-D449 CarbonylContact C-O 3.58Å; S183-D449 VanDerWaalsContact CA-O 3.24Å; S183-D449 WeakPolarHBondContact CA-O 3.5Å; S183-D449 VanDerWaalsContact CB-O 3.24Å; S183-D449 WeakPolarHBondContact CB-O 3.4Å
184Y94.2Very high92.2Very high9 Ų954.4 Ų54.44%0.03528%0.275CS..  trans-58.9152.2156.8-68-80000111.2P306 D370 L446 C447 K448 D449 L450Y184-P306 HydrophobicContact CD1-CG 4.36Å; Y184-P306 HydrophobicContact CD2-CB 4.21Å; Y184-P306 HydrophobicContact CD2-CG 4.35Å; Y184-P306 HydrophobicContact CE2-CB 4.33Å; Y184-P306 HydrophobicContact CG-CB 4.34Å; Y184-P306 HydrophobicContact CG-CG 4.06Å; Y184-D370 HydrophobicContact CE1-CB 4.17Å; Y184-D370 PolarHBondContact OH-OD1 3.2Å; Y184-L446 HydrophobicContact CE2-CB 4.09Å; Y184-L446 HydrophobicContact CE2-CD1 4.5Å; Y184-L446 HydrophobicContact CE2-CD2 3.8Å; Y184-L446 HydrophobicContact CE2-CG 4.34Å; Y184-L446 VanDerWaalsContact OH-CA 3.25Å; Y184-L446 WeakPolarHBondContact OH-CA 3.29Å; Y184-C447 PolarHBondContact OH-N 3.23Å; Y184-K448 HydrophobicContact CD1-CD 4.48Å; Y184-K448 HydrophobicContact CD2-CB 3.95Å; Y184-K448 HydrophobicContact CE1-CB 4.45Å; Y184-K448 HydrophobicContact CE2-CB 3.85Å; Y184-K448 WeakPolarHBondContact CE2-O 3.22Å; Y184-K448 HydrophobicContact CG-CB 4.3Å; Y184-D449 WeakPolarHBondContact CD2-O 3.44Å; Y184-D449 PolarHBondContact N-O 3.22Å; Y184-L450 HydrophobicContact CD2-CB 4.04Å; Y184-L450 HydrophobicContact CD2-CD1 4.12Å; Y184-L450 HydrophobicContact CE2-CB 4.38Å
185R92.2Very high92.5Very high162 Ų16248.4 Ų48.461%0.61124%0.243SC*.  trans-67.7128.2165.1178.9-172.8171.8154.26108.1N187 D262R185-N187 VanDerWaalsContact CZ-OD1 3.25Å; R185-N187 PolarHBondContact NE-OD1 2.64Å; R185-N187 PolarHBondContact NH2-OD1 3.35Å; R185-D262 WeakPolarHBondContact CD-OD1 3.39Å; R185-D262 WeakPolarHBondContact CG-OD1 3.36Å; R185-D262 IonicContact NE-OD1 3.77Å; R185-D262 PolarHBondContact NE-OD1 3.18Å; R185-D262 IonicContact NE-OD2 3.85Å; R185-D262 WeakPolarHBondContact O-CB 3.27Å
186M92Very high92.8Very high5 Ų546.5 Ų46.53%0.02524%0.235CC..  trans-147.266.4179.7-70.9-63.8-67.900108.8R191 Y232 D262 P306 L450 Y451 L452 F453M186-R191 HydrophobicContact CE-CB 4.35Å; M186-R191 HydrophobicContact CE-CG 4.37Å; M186-Y232 WeakPolarHBondContact CE-OH 3.46Å; M186-D262 HydrophobicContact SD-CB 4.09Å; M186-P306 HydrophobicContact SD-CG 3.82Å; M186-L450 HydrophobicContact CG-CD1 4.17Å; M186-L450 HydrophobicContact SD-CD1 4.15Å; M186-Y451 WeakPolarHBondContact CG-O 3.48Å; M186-L452 HydrophobicContact CE-CD2 4.09Å; M186-F453 HydrophobicContact CB-CD2 4.01Å
187N89.8Confident93.2Very high39 Ų3945.6 Ų45.621%0.20923%0.231CC..  trans-134.80.1-172.473.78.3000115.6R185 D262 P458R185-N187 VanDerWaalsContact CZ-OD1 3.25Å; R185-N187 PolarHBondContact NE-OD1 2.64Å; R185-N187 PolarHBondContact NH2-OD1 3.35Å; N187-D262 PolarHBondContact N-OD2 3.48Å; N187-P458 HydrophobicContact CB-CG 4.39Å
188S91.8Very high93.5Very high17 Ų1740.9 Ų40.912%0.11921%0.207CC..  trans-65.6155.2165.743.90000112.1P190 R191 D262S188-P190 CarbonylContact C-O 3.47Å; S188-P190 WeakPolarHBondContact CB-O 3.12Å; S188-P190 CarbonylContact O-C 3.3Å; S188-P190 PolarHBondContact OG-O 2.83Å; S188-R191 WeakPolarHBondContact O-CA 3.48Å; S188-R191 VanDerWaalsContact O-CG 3.29Å; S188-R191 WeakPolarHBondContact O-CG 2.98Å; S188-R191 PolarHBondContact O-N 2.98Å; S188-D262 WeakPolarHBondContact CB-OD2 3.44Å; S188-D262 PolarHBondContact N-OD2 3.32Å; S188-D262 WeakPolarHBondContact OG-CB 3.5Å; S188-D262 PolarHBondContact OG-N 2.82Å; S188-D262 PolarHBondContact OG-OD2 3.17Å
189S91.6Very high93.6Very high73 Ų7337.6 Ų37.651%0.5118%0.183SC..SBendtrans-135.2113.2171.2-171.40000107.9D231S189-D231 WeakPolarHBondContact CA-OD2 3.48Å; S189-D231 VanDerWaalsContact CB-OD2 3.3Å; S189-D231 WeakPolarHBondContact CB-OD2 3.44Å; S189-D231 PolarHBondContact OG-OD2 2.91Å
190P94.3Very high93.6Very high45 Ų4535.3 Ų35.329%0.29217%0.173SC..SBendcis-62.1150-3.429-35.9000112.7S188 G192 D231 H233 V261S188-P190 CarbonylContact C-O 3.47Å; S188-P190 WeakPolarHBondContact CB-O 3.12Å; S188-P190 CarbonylContact O-C 3.3Å; S188-P190 PolarHBondContact OG-O 2.83Å; P190-G192 PolarHBondContact O-N 3.34Å; P190-D231 CarbonylContact C-O 3.55Å; P190-D231 WeakPolarHBondContact CA-O 3.5Å; P190-D231 WeakPolarHBondContact CB-O 3.44Å; P190-H233 HydrophobicContact CB-CB 4.48Å; P190-H233 HydrophobicContact CG-CB 4.45Å; P190-V261 HydrophobicContact CG-CG1 4.1Å; P190-V261 WeakPolarHBondContact O-CG1 3.42Å
191R93.9Very high93.7Very high11 Ų1137.4 Ų37.44%0.04219%0.186CC..  trans-65.6-22.7176.7-96.2110.686.6-142.1-15.7112.9M186 S188 L230 D231 Y232 D262 S263 L452M186-R191 HydrophobicContact CE-CB 4.35Å; M186-R191 HydrophobicContact CE-CG 4.37Å; S188-R191 WeakPolarHBondContact O-CA 3.48Å; S188-R191 VanDerWaalsContact O-CG 3.29Å; S188-R191 WeakPolarHBondContact O-CG 2.98Å; S188-R191 PolarHBondContact O-N 2.98Å; R191-L230 VanDerWaalsContact NH1-C 3.34Å; R191-L230 PolarHBondContact NH1-O 3.15Å; R191-L230 PolarHBondContact NH2-O 2.91Å; R191-D231 PolarHBondContact N-O 2.69Å; R191-Y232 HydrophobicContact CB-CE2 4.43Å; R191-D262 PolarHBondContact O-N 3.03Å; R191-S263 PolarHBondContact O-N 2.87Å; R191-S263 VanDerWaalsContact O-N 3.13Å; R191-S263 PolarHBondContact O-OG 2.99Å; R191-L452 VanDerWaalsContact CZ-O 3.28Å; R191-L452 PolarHBondContact NE-O 3.03Å; R191-L452 PolarHBondContact NH2-O 3.08Å
192G96.2Very high93.8Very high0 Ų029.6 Ų29.60%015%0.152CC..EExtended strand (participates in β ladder)trans-176.1177.8-179.400000113.7P190 Y232 H233 S263P190-G192 PolarHBondContact O-N 3.34Å; G192-Y232 VanDerWaalsContact O-CA 3.31Å; G192-Y232 WeakPolarHBondContact O-CA 3.46Å; G192-H233 PolarHBondContact O-N 3.09Å; G192-S263 WeakPolarHBondContact CA-O 3.49Å
193F97.9Very high93.8Very high13 Ų1326.1 Ų26.16%0.05714%0.138CC..EExtended strand (participates in β ladder)trans-100.4142.7163.9-64-78.1000109.7H233 F252 E257 H258 V261 C264 V265F193-H233 HydrophobicContact CD1-CB 3.75Å; F193-H233 AromaticContact CD1-CD2 3.9Å; F193-H233 HydrophobicContact CE1-CB 3.86Å; F193-H233 AromaticContact CE1-CD2 4Å; F193-F252 HydrophobicContact CB-CE2 3.65Å; F193-F252 HydrophobicContact CB-CZ 3.67Å; F193-E257 HydrophobicContact CE2-CB 3.48Å; F193-E257 VanDerWaalsContact CE2-CB 3.48Å; F193-E257 HydrophobicContact CZ-CB 3.47Å; F193-E257 VanDerWaalsContact CZ-CB 3.47Å; F193-E257 HydrophobicContact CZ-CG 4.25Å; F193-H258 AromaticContact CD2-CE1 3.95Å; F193-H258 AromaticContact CD2-ND1 3.67Å; F193-V261 HydrophobicContact CD2-CG1 4.19Å; F193-V261 HydrophobicContact CD2-CG2 3.86Å; F193-V261 HydrophobicContact CE2-CB 4.46Å; F193-V261 HydrophobicContact CE2-CG1 3.63Å; F193-V261 HydrophobicContact CE2-CG2 3.93Å; F193-V261 HydrophobicContact CZ-CG1 4.21Å; F193-C264 WeakPolarHBondContact O-CA 3.15Å; F193-V265 PolarHBondContact O-N 3.35Å
194A98.3Very high93.2Very high0 Ų030.4 Ų30.40%017%0.167CC..EExtended strand (participates in β ladder)trans-122.3112177.700000110.4F227 Y232 H233 V234 S235 V265A194-F227 HydrophobicContact CB-CB 4.21Å; A194-F227 HydrophobicContact CB-CG 4.41Å; A194-Y232 HydrophobicContact CB-CD1 4.26Å; A194-Y232 HydrophobicContact CB-CG 4.33Å; A194-H233 PolarHBondContact N-O 3.31Å; A194-V234 HydrophobicContact CB-CB 4.35Å; A194-V234 HydrophobicContact CB-CG1 4.1Å; A194-V234 HydrophobicContact CB-CG2 4.11Å; A194-V234 CarbonylContact O-C 3.57Å; A194-V234 WeakPolarHBondContact O-CA 3.48Å; A194-S235 PolarHBondContact O-N 3.24Å; A194-S235 PolarHBondContact O-OG 3.19Å; A194-V265 CarbonylContact C-O 3.04Å; A194-V265 WeakPolarHBondContact CA-O 3.49Å; A194-V265 HydrophobicContact CB-CB 3.9Å; A194-V265 HydrophobicContact CB-CG1 4.45Å
195L98.6Very high92.7Very high0 Ų035.6 Ų35.60%020%0.204CC..EExtended strand (participates in β ladder)trans-86.6126.7170.6177.255.4000109.2I197 I249 F252 V265 V266 S267L195-I197 HydrophobicContact CD1-CD1 4.43Å; L195-I197 HydrophobicContact CD1-CG1 3.92Å; L195-I197 HydrophobicContact CD2-CD1 4.19Å; L195-I197 HydrophobicContact CD2-CG1 4.41Å; L195-I197 HydrophobicContact CG-CD1 4.43Å; L195-I197 HydrophobicContact CG-CG1 4.09Å; L195-I249 HydrophobicContact CD2-CG1 4.06Å; L195-F252 HydrophobicContact CB-CD1 4.34Å; L195-F252 HydrophobicContact CB-CD2 3.75Å; L195-F252 HydrophobicContact CB-CE1 4.24Å; L195-F252 HydrophobicContact CB-CE2 3.64Å; L195-F252 HydrophobicContact CB-CG 4.09Å; L195-F252 HydrophobicContact CB-CZ 3.89Å; L195-F252 HydrophobicContact CD2-CB 3.99Å; L195-F252 HydrophobicContact CD2-CD1 4.37Å; L195-F252 HydrophobicContact CD2-CD2 4.34Å; L195-F252 HydrophobicContact CD2-CG 4Å; L195-F252 HydrophobicContact CG-CD2 4.46Å; L195-V265 PolarHBondContact N-O 3.07Å; L195-V266 HydrophobicContact CD2-CG1 4.39Å; L195-V266 CarbonylContact O-C 3.46Å; L195-V266 WeakPolarHBondContact O-CA 3.49Å; L195-S267 PolarHBondContact O-N 2.7Å
196V98.5Very high92.1Very high0 Ų030.5 Ų30.50%019%0.193CC..EExtended strand (participates in β ladder)trans-120.5118.1168.1-175.50000108D220 L223 V234 S235 V236 H237 S267 L269V196-D220 HydrophobicContact CG1-CB 3.85Å; V196-L223 HydrophobicContact CG1-CD1 4.36Å; V196-L223 HydrophobicContact CG2-CB 4.32Å; V196-V234 HydrophobicContact CG2-CG1 3.92Å; V196-S235 PolarHBondContact N-O 3.2Å; V196-V236 HydrophobicContact CB-CG1 4.35Å; V196-V236 HydrophobicContact CB-CG2 4.19Å; V196-V236 HydrophobicContact CG1-CG1 4.4Å; V196-V236 HydrophobicContact CG2-CG2 4.49Å; V196-V236 CarbonylContact O-C 3.57Å; V196-V236 WeakPolarHBondContact O-CA 3.36Å; V196-H237 PolarHBondContact O-N 3.5Å; V196-S267 WeakPolarHBondContact CA-O 3.35Å; V196-L269 HydrophobicContact CG1-CD1 4.3Å
197I98.2Very high91.6Very high1 Ų130.6 Ų30.61%0.00520%0.195CC..EExtended strand (participates in β ladder)trans-108.9122.6169.7-58.9179.7000107.8L195 H237 L240 M245 C248 I249 S267 L268 L269L195-I197 HydrophobicContact CD1-CD1 4.43Å; L195-I197 HydrophobicContact CD1-CG1 3.92Å; L195-I197 HydrophobicContact CD2-CD1 4.19Å; L195-I197 HydrophobicContact CD2-CG1 4.41Å; L195-I197 HydrophobicContact CG-CD1 4.43Å; L195-I197 HydrophobicContact CG-CG1 4.09Å; I197-H237 WeakPolarHBondContact CA-O 3.41Å; I197-L240 HydrophobicContact CD1-CD1 4.24Å; I197-L240 HydrophobicContact CG1-CD1 4.41Å; I197-L240 HydrophobicContact CG2-CB 4.47Å; I197-L240 HydrophobicContact CG2-CD1 4.1Å; I197-L240 HydrophobicContact CG2-CG 4.45Å; I197-M245 HydrophobicContact CD1-CB 4.45Å; I197-M245 HydrophobicContact CG2-CE 4.02Å; I197-M245 HydrophobicContact CG2-CG 4.08Å; I197-C248 HydrophobicContact CD1-CB 4.27Å; I197-I249 HydrophobicContact CD1-CD1 4.28Å; I197-I249 HydrophobicContact CD1-CG1 4.01Å; I197-S267 PolarHBondContact N-O 3.48Å; I197-L268 HydrophobicContact CB-CD2 3.89Å; I197-L268 HydrophobicContact CD1-CD2 3.92Å; I197-L268 HydrophobicContact CG1-CD2 4.06Å; I197-L269 PolarHBondContact O-N 3.13Å
198S96.9Very high90.8Very high0 Ų034 Ų340%022%0.219CC..EExtended strand (participates in β ladder)trans-128.899.3-174-172.80000110.8G216 D220 H237 R238 D239S198-G216 PolarHBondContact OG-O 2.7Å; S198-D220 WeakPolarHBondContact CB-OD2 3.27Å; S198-D220 PolarHBondContact OG-OD2 2.92Å; S198-H237 PolarHBondContact N-O 2.64Å; S198-R238 WeakPolarHBondContact O-CA 3.26Å; S198-D239 PolarHBondContact O-N 3.43Å
199N94.4Very high90Very high0 Ų036.7 Ų36.70%025%0.249CC..  trans-91.4106.6176.3-70.6-1.2000108.4F202 R213 D239 L240 M245 L269 S270 Y278 T280N199-F202 HydrophobicContact CB-CE1 4.15Å; N199-F202 HydrophobicContact CB-CE2 4.38Å; N199-F202 HydrophobicContact CB-CZ 3.68Å; N199-R213 WeakPolarHBondContact O-CD 3.45Å; N199-R213 PolarHBondContact O-NH1 3.48Å; N199-D239 PolarHBondContact OD1-N 2.78Å; N199-L240 PolarHBondContact ND2-O 3.18Å; N199-L240 PolarHBondContact OD1-N 3.1Å; N199-M245 PolarHBondContact ND2-SD 3.05Å; N199-M245 VanDerWaalsContact ND2-SD 3.39Å; N199-L269 PolarHBondContact N-O 3.02Å; N199-S270 WeakPolarHBondContact CB-OG 3.5Å; N199-Y278 PolarHBondContact ND2-O 3.06Å; N199-T280 HydrophobicContact CB-CG2 3.96Å
200V90.5Very high89.5Confident7 Ų734.8 Ų34.84%0.04223%0.233CC..  trans-103.7-49.1-176.9177.40000109.9P212 R213 E217 D239V200-P212 CarbonylContact O-C 3.19Å; V200-R213 PolarHBondContact O-N 3.28Å; V200-E217 HydrophobicContact CG1-CG 4.03Å; V200-E217 HydrophobicContact CG2-CG 4.24Å; V200-D239 WeakPolarHBondContact CA-OD1 3.39Å; V200-D239 PolarHBondContact N-OD1 2.88Å
201T90.4Very high88.8Confident76 Ų7638.9 Ų38.947%0.46625%0.252SS..  trans-101.7146.8176.573.90000111D239 T280T201-D239 WeakPolarHBondContact CB-OD2 3.37Å; T201-D239 PolarHBondContact N-OD1 3.09Å; T201-D239 PolarHBondContact OG1-OD2 2.66Å; T201-T280 WeakPolarHBondContact O-CG2 3.48Å
202F88.9Confident88.1Confident13 Ų1341.6 Ų41.66%0.05727%0.272CS..  trans-130.3139.2-179-66-98.2000107.8N199 S204 A207 L210 R213 S270 H271 T280N199-F202 HydrophobicContact CB-CE1 4.15Å; N199-F202 HydrophobicContact CB-CE2 4.38Å; N199-F202 HydrophobicContact CB-CZ 3.68Å; F202-S204 PolarHBondContact O-N 3.01Å; F202-S204 VanDerWaalsContact O-N 3.17Å; F202-A207 HydrophobicContact CB-CB 4.38Å; F202-L210 HydrophobicContact CB-CB 4.06Å; F202-L210 HydrophobicContact CD1-CB 4.08Å; F202-L210 HydrophobicContact CD1-CD1 3.58Å; F202-L210 HydrophobicContact CD1-CG 4.5Å; F202-L210 HydrophobicContact CE1-CD1 3.95Å; F202-L210 HydrophobicContact CG-CB 3.97Å; F202-L210 HydrophobicContact CG-CD1 4.32Å; F202-R213 HydrophobicContact CE2-CG 3.96Å; F202-S270 WeakPolarHBondContact CZ-OG 3.5Å; F202-H271 AromaticContact CD2-CD2 3.91Å; F202-H271 AromaticContact CE1-CD2 3.95Å; F202-H271 AromaticContact CE2-CD2 3.48Å; F202-H271 VanDerWaalsContact CE2-CD2 3.48Å; F202-H271 WeakPolarHBondContact CE2-CD2 3.49Å; F202-H271 AromaticContact CE2-NE2 4Å; F202-H271 HydrophobicContact CZ-CB 4.4Å; F202-H271 AromaticContact CZ-CD2 3.51Å; F202-T280 HydrophobicContact CD1-CG2 4.49Å
203D86.6Confident87.6Confident75 Ų7542 Ų4240%0.40127%0.273SS..  trans-69.5114.1-179.1162.836.3000109.8C205 S206 A207 T280D203-C205 PolarHBondContact O-N 3.16Å; D203-C205 VanDerWaalsContact O-N 3.1Å; D203-C205 WeakPolarHBondContact OD1-CB 3.43Å; D203-C205 PolarHBondContact OD1-N 3.07Å; D203-S206 WeakPolarHBondContact CB-OG 3.22Å; D203-S206 PolarHBondContact O-N 3.39Å; D203-S206 VanDerWaalsContact OD2-CB 3.28Å; D203-S206 WeakPolarHBondContact OD2-CB 3.23Å; D203-S206 PolarHBondContact OD2-N 3.38Å; D203-S206 PolarHBondContact OD2-OG 2.8Å; D203-A207 WeakPolarHBondContact O-CA 3.48Å; D203-A207 WeakPolarHBondContact O-CB 3.38Å; D203-A207 PolarHBondContact O-N 3.36Å; D203-T280 PolarHBondContact N-O 3.27Å
204S82.5Confident86.4Confident92 Ų9247.9 Ų47.964%0.64330%0.299SS*.THydrogen-bonded Turntrans-65.8-11.8-178.7-500000114.1F202F202-S204 PolarHBondContact O-N 3.01Å; F202-S204 VanDerWaalsContact O-N 3.17Å
205C83.1Confident85.3Confident118 Ų11848.1 Ų48.180%0.79730%0.301SS*.THydrogen-bonded Turntrans-82.5-42.9173.9-60.40000112.4D203D203-C205 PolarHBondContact O-N 3.16Å; D203-C205 VanDerWaalsContact O-N 3.1Å; D203-C205 WeakPolarHBondContact OD1-CB 3.43Å; D203-C205 PolarHBondContact OD1-N 3.07Å
206S80.5Confident84.3Confident56 Ų5648.1 Ų48.139%0.39230%0.301SS..THydrogen-bonded Turntrans-92.8-27.1179.755.20000114.2D203 D281D203-S206 WeakPolarHBondContact CB-OG 3.22Å; D203-S206 PolarHBondContact O-N 3.39Å; D203-S206 VanDerWaalsContact OD2-CB 3.28Å; D203-S206 WeakPolarHBondContact OD2-CB 3.23Å; D203-S206 PolarHBondContact OD2-N 3.38Å; D203-S206 PolarHBondContact OD2-OG 2.8Å; S206-D281 WeakPolarHBondContact OG-CA 3.43Å
207A80.2Confident83.8Confident7 Ų752.4 Ų52.46%0.05832%0.321CS..  trans-125.752.2-177.200000113.6F202 D203 G209 L210F202-A207 HydrophobicContact CB-CB 4.38Å; D203-A207 WeakPolarHBondContact O-CA 3.48Å; D203-A207 WeakPolarHBondContact O-CB 3.38Å; D203-A207 PolarHBondContact O-N 3.36Å; A207-G209 PolarHBondContact O-N 3.26Å; A207-L210 HydrophobicContact CB-CB 4.23Å; A207-L210 HydrophobicContact CB-CD1 4.04Å; A207-L210 HydrophobicContact CB-CG 4.21Å; A207-L210 PolarHBondContact O-N 3.41Å
208P73.1Confident83.3Confident111 Ų11154.1 Ų54.172%0.72133%0.332SS*.THydrogen-bonded Turntrans-63.7-4.7-174.227.1-36.9000115.9
209G74.6Confident83Confident73 Ų7354.2 Ų54.275%0.75333%0.332SS*.THydrogen-bonded Turntrans-104.75.9174.200000114.9A207A207-G209 PolarHBondContact O-N 3.26Å
210L81.8Confident82.9Confident32 Ų3254.2 Ų54.217%0.16833%0.332CS..  trans-112.399.3-178.2-63.8-171.5000111.1F202 A207 H271 Y278F202-L210 HydrophobicContact CB-CB 4.06Å; F202-L210 HydrophobicContact CD1-CB 4.08Å; F202-L210 HydrophobicContact CD1-CD1 3.58Å; F202-L210 HydrophobicContact CD1-CG 4.5Å; F202-L210 HydrophobicContact CE1-CD1 3.95Å; F202-L210 HydrophobicContact CG-CB 3.97Å; F202-L210 HydrophobicContact CG-CD1 4.32Å; A207-L210 HydrophobicContact CB-CB 4.23Å; A207-L210 HydrophobicContact CB-CD1 4.04Å; A207-L210 HydrophobicContact CB-CG 4.21Å; A207-L210 PolarHBondContact O-N 3.41Å; L210-H271 HydrophobicContact CD1-CB 4.48Å; L210-H271 HydrophobicContact CD2-CB 4.04Å; L210-Y278 HydrophobicContact CD1-CD1 3.87Å; L210-Y278 HydrophobicContact CD1-CD2 4.05Å; L210-Y278 HydrophobicContact CD1-CE1 4.45Å; L210-Y278 HydrophobicContact CD1-CG 3.64Å; L210-Y278 HydrophobicContact CD2-CD2 4.12Å; L210-Y278 HydrophobicContact CD2-CE2 4.12Å
211D78.9Confident83.1Confident131 Ų13156.3 Ų56.370%0.70134%0.341SS*.  trans-63.7145.5178.4-82.9-50.7000112.9R213 H271D211-R213 PolarHBondContact O-N 3.36Å; D211-H271 PolarHBondContact O-NE2 3.49Å
212P80.4Confident83.3Confident69 Ų6953.4 Ų53.445%0.44832%0.324SS..  trans-57.4125.6176.2-25.934.8000113V200 K214V200-P212 CarbonylContact O-C 3.19Å; P212-K214 PolarHBondContact O-N 3.11Å
213R84.4Confident83.6Confident7 Ų752.8 Ų52.83%0.02632%0.321CS..  trans-7858.9-178-68.7173.171-98.55112.1N199 V200 F202 D211 G215 G216 L269 S270 H271 Q312 R385N199-R213 WeakPolarHBondContact O-CD 3.45Å; N199-R213 PolarHBondContact O-NH1 3.48Å; V200-R213 PolarHBondContact O-N 3.28Å; F202-R213 HydrophobicContact CE2-CG 3.96Å; D211-R213 PolarHBondContact O-N 3.36Å; R213-G215 PolarHBondContact O-N 3.33Å; R213-G216 PolarHBondContact O-N 3.48Å; R213-L269 PolarHBondContact NH1-O 3.3Å; R213-S270 PolarHBondContact NE-O 3.24Å; R213-S270 PolarHBondContact NH2-O 2.96Å; R213-H271 WeakPolarHBondContact CG-NE2 3.21Å; R213-Q312 PolarHBondContact NH2-O 2.9Å; R213-R385 PolarHBondContact O-NH1 3.38Å; R213-R385 PolarHBondContact O-NH2 2.86Å
214K74.6Confident84.1Confident138 Ų13853.8 Ų53.860%0.632%0.319SS*.THydrogen-bonded Turntrans-45.1123.4172.9-65.1178.4-179.1175.50111.6P212 R385 T387P212-K214 PolarHBondContact O-N 3.11Å; K214-R385 VanDerWaalsContact O-CZ 3.28Å; K214-R385 PolarHBondContact O-NH1 3.13Å; K214-R385 PolarHBondContact O-NH2 3.45Å; K214-T387 HydrophobicContact CB-CG2 4.3Å
215G74.9Confident84.8Confident4 Ų454 Ų544%0.04131%0.308CS..THydrogen-bonded Turntrans96.7-2.2-176.400000114.9R213 E217 V218R213-G215 PolarHBondContact O-N 3.33Å; G215-E217 VanDerWaalsContact C-N 3.27Å; G215-E217 VanDerWaalsContact C-OE2 3.25Å; G215-E217 VanDerWaalsContact CA-OE2 3.24Å; G215-E217 WeakPolarHBondContact CA-OE2 3.49Å; G215-E217 PolarHBondContact N-OE2 3Å; G215-V218 WeakPolarHBondContact O-CB 3.44Å; G215-V218 PolarHBondContact O-N 3.26Å
216G76.9Confident85.4Confident0 Ų048.4 Ų48.40%027%0.271CS..Hα-helixtrans-73.6-22.9174.900000112.7S198 R213 V218 D219 D220S198-G216 PolarHBondContact OG-O 2.7Å; R213-G216 PolarHBondContact O-N 3.48Å; G216-V218 PolarHBondContact O-N 3.4Å; G216-D219 WeakPolarHBondContact O-CB 3.37Å; G216-D219 PolarHBondContact O-N 3.47Å; G216-D220 PolarHBondContact O-N 3.14Å; G216-D220 VanDerWaalsContact O-N 3.07Å
217E87Confident86.2Confident91 Ų9145.9 Ų45.943%0.42525%0.252SS..Hα-helixtrans-61.5-27.5169-4692137.800111.8V200 G215 E221V200-E217 HydrophobicContact CG1-CG 4.03Å; V200-E217 HydrophobicContact CG2-CG 4.24Å; G215-E217 VanDerWaalsContact C-N 3.27Å; G215-E217 VanDerWaalsContact C-OE2 3.25Å; G215-E217 VanDerWaalsContact CA-OE2 3.24Å; G215-E217 WeakPolarHBondContact CA-OE2 3.49Å; G215-E217 PolarHBondContact N-OE2 3Å; E217-E221 WeakPolarHBondContact O-CB 3.21Å
218V88Confident87Confident37 Ų3749 Ų4922%0.22427%0.271CS..Hα-helixtrans-76.9-42.4174.7-173.80000109.9P163 G215 G216 V222P163-V218 HydrophobicContact CG-CG1 3.55Å; G215-V218 WeakPolarHBondContact O-CB 3.44Å; G215-V218 PolarHBondContact O-N 3.26Å; G216-V218 PolarHBondContact O-N 3.4Å; V218-V222 HydrophobicContact CG1-CG2 4.32Å; V218-V222 VanDerWaalsContact O-CB 3.28Å; V218-V222 WeakPolarHBondContact O-CB 3.09Å; V218-V222 WeakPolarHBondContact O-CG2 3.24Å; V218-V222 PolarHBondContact O-N 2.86Å
219D90.6Very high88Confident2 Ų246.3 Ų46.31%0.01125%0.249CC..Hα-helixtrans-61.6-49.3179.8-66.8-42.4000111.8G216 E221 V222 L223 L269 G390 S391 I394G216-D219 WeakPolarHBondContact O-CB 3.37Å; G216-D219 PolarHBondContact O-N 3.47Å; D219-E221 PolarHBondContact O-N 3.12Å; D219-V222 PolarHBondContact O-N 2.93Å; D219-L223 WeakPolarHBondContact O-CG 3.4Å; D219-L223 PolarHBondContact O-N 3.33Å; D219-L269 HydrophobicContact CB-CD1 3.8Å; D219-G390 VanDerWaalsContact OD1-CA 3.25Å; D219-G390 WeakPolarHBondContact OD1-CA 3.4Å; D219-S391 PolarHBondContact OD1-N 2.84Å; D219-S391 PolarHBondContact OD2-N 2.91Å; D219-I394 HydrophobicContact CB-CB 4.33Å; D219-I394 HydrophobicContact CB-CG1 4.22Å; D219-I394 HydrophobicContact CB-CG2 4Å; D219-I394 WeakPolarHBondContact OD1-CB 3.18Å
220D93.3Very high89Confident0 Ų042.9 Ų42.90%021%0.213CC..Hα-helixtrans-69.8-32.7-177.967.849.6000113.6V196 S198 G216 R224 V236 R238 L269V196-D220 HydrophobicContact CG1-CB 3.85Å; S198-D220 WeakPolarHBondContact CB-OD2 3.27Å; S198-D220 PolarHBondContact OG-OD2 2.92Å; G216-D220 PolarHBondContact O-N 3.14Å; G216-D220 VanDerWaalsContact O-N 3.07Å; D220-R224 VanDerWaalsContact O-CB 3.26Å; D220-R224 WeakPolarHBondContact O-CB 3.5Å; D220-R224 PolarHBondContact O-N 3.27Å; D220-V236 HydrophobicContact CB-CG1 4.16Å; D220-R238 VanDerWaalsContact CG-NE 3.34Å; D220-R238 IonicContact OD1-CZ 3.14Å; D220-R238 VanDerWaalsContact OD1-CZ 3.31Å; D220-R238 IonicContact OD1-NE 2.74Å; D220-R238 PolarHBondContact OD1-NE 3.4Å; D220-R238 IonicContact OD1-NH2 2.71Å; D220-R238 PolarHBondContact OD1-NH2 2.89Å; D220-R238 IonicContact OD2-CZ 3.19Å; D220-R238 IonicContact OD2-NE 3.85Å; D220-R238 PolarHBondContact OD2-NE 2.95Å; D220-R238 IonicContact OD2-NH2 3.93Å; D220-L269 HydrophobicContact CB-CD1 4.04Å
221E94.3Very high89.7Confident51 Ų5143.8 Ų43.824%0.23822%0.218CC..Hα-helixtrans-72.6-35.2174.5176.662.3-172.900111.9E217 D219 R224 K225E217-E221 WeakPolarHBondContact O-CB 3.21Å; D219-E221 PolarHBondContact O-N 3.12Å; E221-R224 VanDerWaalsContact CD-NH2 3.26Å; E221-R224 IonicContact OE1-CZ 3.64Å; E221-R224 IonicContact OE1-NE 2.83Å; E221-R224 IonicContact OE1-NH2 3.57Å; E221-R224 PolarHBondContact OE1-NH2 2.99Å; E221-R224 IonicContact OE2-CZ 2.9Å; E221-R224 VanDerWaalsContact OE2-CZ 3.27Å; E221-R224 IonicContact OE2-NE 3.24Å; E221-R224 PolarHBondContact OE2-NE 3.5Å; E221-R224 IonicContact OE2-NH2 3.11Å; E221-R224 PolarHBondContact OE2-NH2 2.94Å; E221-K225 WeakPolarHBondContact O-CG 3.33Å; E221-K225 PolarHBondContact O-N 3.26Å; E221-K225 WeakPolarHBondContact OE1-CE 3.3Å; E221-K225 IonicContact OE1-NZ 3.05Å; E221-K225 PolarHBondContact OE1-NZ 3.41Å; E221-K225 VanDerWaalsContact OE1-NZ 3.16Å
222V94.4Very high90.5Very high15 Ų1537.9 Ų37.99%0.09119%0.186CC..Hα-helixtrans-63.3-48.8171.5161.50000110.5P163 V218 D219 K225 V226 I394 N398P163-V222 HydrophobicContact CB-CG2 3.78Å; P163-V222 HydrophobicContact CG-CG2 4.14Å; V218-V222 HydrophobicContact CG1-CG2 4.32Å; V218-V222 VanDerWaalsContact O-CB 3.28Å; V218-V222 WeakPolarHBondContact O-CB 3.09Å; V218-V222 WeakPolarHBondContact O-CG2 3.24Å; V218-V222 PolarHBondContact O-N 2.86Å; D219-V222 PolarHBondContact O-N 2.93Å; V222-K225 PolarHBondContact O-N 2.9Å; V222-V226 PolarHBondContact O-N 3Å; V222-I394 HydrophobicContact CG1-CG2 4.14Å; V222-N398 HydrophobicContact CG1-CB 3.48Å; V222-N398 VanDerWaalsContact CG1-CB 3.48Å; V222-N398 VanDerWaalsContact CG1-CG 3.47Å
223L96.3Very high91.4Very high0 Ų039.6 Ų39.60%019%0.188CC..Hα-helixtrans-62.8-42.3176.2-67.9-177000111.7V196 D219 K225 V226 F227 L269 I394 L397V196-L223 HydrophobicContact CG1-CD1 4.36Å; V196-L223 HydrophobicContact CG2-CB 4.32Å; D219-L223 WeakPolarHBondContact O-CG 3.4Å; D219-L223 PolarHBondContact O-N 3.33Å; L223-K225 VanDerWaalsContact C-N 3.35Å; L223-K225 PolarHBondContact O-N 2.99Å; L223-V226 PolarHBondContact O-N 3.49Å; L223-F227 HydrophobicContact CB-CD2 4.19Å; L223-F227 HydrophobicContact CB-CE2 4.17Å; L223-F227 HydrophobicContact CD2-CE2 3.87Å; L223-F227 HydrophobicContact CD2-CZ 4.49Å; L223-F227 HydrophobicContact CG-CE2 4.47Å; L223-F227 WeakPolarHBondContact O-CB 3.43Å; L223-F227 WeakPolarHBondContact O-CD2 3.29Å; L223-F227 PolarHBondContact O-N 2.77Å; L223-L269 HydrophobicContact CD1-CD1 4.13Å; L223-L269 HydrophobicContact CD1-CD2 3.95Å; L223-I394 HydrophobicContact CD1-CD1 4.17Å; L223-I394 HydrophobicContact CD1-CG2 4.48Å; L223-I394 HydrophobicContact CD2-CD1 4.4Å; L223-I394 HydrophobicContact CD2-CG2 3.91Å; L223-I394 HydrophobicContact CG-CG2 3.92Å; L223-L397 HydrophobicContact CD2-CD2 4.4Å
224R97Very high92Very high95 Ų9540.6 Ų40.636%0.35820%0.195SC..Hα-helixtrans-57.9-46.3176.3-169.5-172.869.181.4-1.2111.5D220 E221 T228 V234 V236D220-R224 VanDerWaalsContact O-CB 3.26Å; D220-R224 WeakPolarHBondContact O-CB 3.5Å; D220-R224 PolarHBondContact O-N 3.27Å; E221-R224 VanDerWaalsContact CD-NH2 3.26Å; E221-R224 IonicContact OE1-CZ 3.64Å; E221-R224 IonicContact OE1-NE 2.83Å; E221-R224 IonicContact OE1-NH2 3.57Å; E221-R224 PolarHBondContact OE1-NH2 2.99Å; E221-R224 IonicContact OE2-CZ 2.9Å; E221-R224 VanDerWaalsContact OE2-CZ 3.27Å; E221-R224 IonicContact OE2-NE 3.24Å; E221-R224 PolarHBondContact OE2-NE 3.5Å; E221-R224 IonicContact OE2-NH2 3.11Å; E221-R224 PolarHBondContact OE2-NH2 2.94Å; R224-T228 VanDerWaalsContact O-CB 3.29Å; R224-T228 WeakPolarHBondContact O-CB 3.4Å; R224-T228 PolarHBondContact O-N 2.78Å; R224-T228 PolarHBondContact O-OG1 2.74Å; R224-V234 HydrophobicContact CG-CB 4.35Å; R224-V234 HydrophobicContact CG-CG1 4.27Å; R224-V236 HydrophobicContact CB-CG2 3.98Å; R224-V236 HydrophobicContact CG-CG2 3.88Å
225K95.9Very high93.1Very high98 Ų9835.2 Ų35.243%0.42618%0.175SC..Hα-helixtrans-62.3-55.6177.3-75.6169.2178.6152.60111.8E221 V222 L223 F227 T228 E229E221-K225 WeakPolarHBondContact O-CG 3.33Å; E221-K225 PolarHBondContact O-N 3.26Å; E221-K225 WeakPolarHBondContact OE1-CE 3.3Å; E221-K225 IonicContact OE1-NZ 3.05Å; E221-K225 PolarHBondContact OE1-NZ 3.41Å; E221-K225 VanDerWaalsContact OE1-NZ 3.16Å; V222-K225 PolarHBondContact O-N 2.9Å; L223-K225 VanDerWaalsContact C-N 3.35Å; L223-K225 PolarHBondContact O-N 2.99Å; K225-F227 PolarHBondContact O-N 2.84Å; K225-T228 PolarHBondContact O-N 2.65Å; K225-E229 WeakPolarHBondContact O-CG 3.29Å; K225-E229 PolarHBondContact O-N 2.77Å
226V96.1Very high94.2Very high0 Ų037.1 Ų37.10%019%0.185CC..Hα-helixtrans-65.1-38.5-173.376.50000112.2V168 V222 L223 E229 L230 L401 R402V168-V226 HydrophobicContact CG2-CG2 3.88Å; V222-V226 PolarHBondContact O-N 3Å; L223-V226 PolarHBondContact O-N 3.49Å; V226-E229 PolarHBondContact O-N 2.79Å; V226-L230 HydrophobicContact CG2-CD1 4.21Å; V226-L230 WeakPolarHBondContact O-CB 3.31Å; V226-L230 WeakPolarHBondContact O-CD1 3.36Å; V226-L230 VanDerWaalsContact O-CG 3.22Å; V226-L230 WeakPolarHBondContact O-CG 3.26Å; V226-L230 PolarHBondContact O-N 2.84Å; V226-L401 HydrophobicContact CG1-CD1 4.27Å; V226-L401 HydrophobicContact CG2-CB 3.92Å; V226-L401 HydrophobicContact CG2-CD1 4.4Å; V226-R402 HydrophobicContact CG2-CG 3.95Å
227F97.4Very high95.2Very high2 Ų240.7 Ų40.71%0.00920%0.202CC..Hα-helixtrans-72.7-32.2175.8-67.9-51.6000113.1A194 L223 K225 L230 D231 Y232 V234 V265 F310 L401A194-F227 HydrophobicContact CB-CB 4.21Å; A194-F227 HydrophobicContact CB-CG 4.41Å; L223-F227 HydrophobicContact CB-CD2 4.19Å; L223-F227 HydrophobicContact CB-CE2 4.17Å; L223-F227 HydrophobicContact CD2-CE2 3.87Å; L223-F227 HydrophobicContact CD2-CZ 4.49Å; L223-F227 HydrophobicContact CG-CE2 4.47Å; L223-F227 WeakPolarHBondContact O-CB 3.43Å; L223-F227 WeakPolarHBondContact O-CD2 3.29Å; L223-F227 PolarHBondContact O-N 2.77Å; K225-F227 PolarHBondContact O-N 2.84Å; F227-L230 HydrophobicContact CD1-CD1 4Å; F227-L230 HydrophobicContact CE1-CD1 4.34Å; F227-L230 CarbonylContact O-C 3.55Å; F227-L230 VanDerWaalsContact O-C 3.3Å; F227-L230 WeakPolarHBondContact O-CA 3.12Å; F227-L230 PolarHBondContact O-N 2.9Å; F227-D231 PolarHBondContact O-N 2.83Å; F227-Y232 HydrophobicContact CB-CD2 4.46Å; F227-Y232 HydrophobicContact CB-CG 4.48Å; F227-Y232 HydrophobicContact CD1-CD2 4.34Å; F227-Y232 WeakPolarHBondContact O-CB 3.31Å; F227-Y232 PolarHBondContact O-N 2.97Å; F227-V234 HydrophobicContact CB-CG2 3.77Å; F227-V265 HydrophobicContact CD1-CG2 4.26Å; F227-V265 HydrophobicContact CD2-CG1 4.28Å; F227-V265 HydrophobicContact CE1-CG1 4.13Å; F227-V265 HydrophobicContact CE1-CG2 4.06Å; F227-V265 HydrophobicContact CE2-CG1 3.75Å; F227-V265 HydrophobicContact CZ-CG1 3.7Å; F227-V265 HydrophobicContact CZ-CG2 4.46Å; F227-F310 HydrophobicContact CE1-CE2 4.23Å; F227-F310 HydrophobicContact CE2-CD2 4.47Å; F227-F310 AromaticContact CZ-CD2 3.9Å; F227-F310 HydrophobicContact CZ-CD2 3.9Å; F227-F310 AromaticContact CZ-CE2 3.62Å; F227-F310 HydrophobicContact CZ-CE2 3.62Å; F227-L401 HydrophobicContact CE1-CD1 4.07Å; F227-L401 HydrophobicContact CZ-CD1 4.27Å
228T96.3Very high95.7Very high74 Ų7442.5 Ų42.545%0.45421%0.205SC..Hα-helixtrans-65.4-41.4171.1-55.70000111.3R224 K225 L230 D231R224-T228 VanDerWaalsContact O-CB 3.29Å; R224-T228 WeakPolarHBondContact O-CB 3.4Å; R224-T228 PolarHBondContact O-N 2.78Å; R224-T228 PolarHBondContact O-OG1 2.74Å; K225-T228 PolarHBondContact O-N 2.65Å; T228-L230 PolarHBondContact O-N 3.17Å; T228-D231 WeakPolarHBondContact O-CA 3.37Å; T228-D231 PolarHBondContact O-N 3.07Å
229E94.7Very high96.1Very high54 Ų5443.3 Ų43.325%0.25221%0.208SC..Hα-helixtrans-68.5-22.7174.3-70.4174.8-112.600113.2P167 V168 K225 V226 D231 R402P167-E229 VanDerWaalsContact CA-OE2 3.3Å; P167-E229 WeakPolarHBondContact CA-OE2 3.48Å; V168-E229 HydrophobicContact CB-CB 4.05Å; V168-E229 HydrophobicContact CG2-CB 3.58Å; V168-E229 HydrophobicContact CG2-CG 4.48Å; V168-E229 PolarHBondContact N-OE2 2.84Å; K225-E229 WeakPolarHBondContact O-CG 3.29Å; K225-E229 PolarHBondContact O-N 2.77Å; V226-E229 PolarHBondContact O-N 2.79Å; E229-D231 VanDerWaalsContact C-N 3.26Å; E229-R402 VanDerWaalsContact CD-NH1 3.25Å; E229-R402 IonicContact OE1-CZ 2.84Å; E229-R402 IonicContact OE1-NH1 2.74Å; E229-R402 PolarHBondContact OE1-NH1 3.38Å; E229-R402 IonicContact OE1-NH2 3.77Å; E229-R402 PolarHBondContact OE1-NH2 3.49Å; E229-R402 IonicContact OE2-NH1 3.15Å; E229-R402 PolarHBondContact OE2-NH1 3.17Å
230L95.4Very high96.4Very high0 Ų044.9 Ų44.90%022%0.216CC..THydrogen-bonded Turntrans-86.615.8167.9-67.3164000112.8V168 R191 V226 F227 T228 Y232 L401 A405 L452 P454V168-L230 HydrophobicContact CG1-CD2 3.88Å; V168-L230 HydrophobicContact CG1-CG 4.4Å; V168-L230 HydrophobicContact CG2-CG 4.49Å; R191-L230 VanDerWaalsContact NH1-C 3.34Å; R191-L230 PolarHBondContact NH1-O 3.15Å; R191-L230 PolarHBondContact NH2-O 2.91Å; V226-L230 HydrophobicContact CG2-CD1 4.21Å; V226-L230 WeakPolarHBondContact O-CB 3.31Å; V226-L230 WeakPolarHBondContact O-CD1 3.36Å; V226-L230 VanDerWaalsContact O-CG 3.22Å; V226-L230 WeakPolarHBondContact O-CG 3.26Å; V226-L230 PolarHBondContact O-N 2.84Å; F227-L230 HydrophobicContact CD1-CD1 4Å; F227-L230 HydrophobicContact CE1-CD1 4.34Å; F227-L230 CarbonylContact O-C 3.55Å; F227-L230 VanDerWaalsContact O-C 3.3Å; F227-L230 WeakPolarHBondContact O-CA 3.12Å; F227-L230 PolarHBondContact O-N 2.9Å; T228-L230 PolarHBondContact O-N 3.17Å; L230-Y232 VanDerWaalsContact C-N 3.29Å; L230-Y232 HydrophobicContact CB-CD2 3.8Å; L230-Y232 HydrophobicContact CB-CE2 3.91Å; L230-Y232 VanDerWaalsContact O-CD2 3.24Å; L230-Y232 WeakPolarHBondContact O-CD2 3.37Å; L230-Y232 WeakPolarHBondContact O-CE2 3.39Å; L230-Y232 PolarHBondContact O-N 3.3Å; L230-L401 HydrophobicContact CD1-CB 4.46Å; L230-L401 HydrophobicContact CD1-CD1 4.39Å; L230-L401 HydrophobicContact CD1-CD2 4.33Å; L230-A405 HydrophobicContact CD2-CB 3.98Å; L230-L452 HydrophobicContact CD1-CD1 4.09Å; L230-L452 HydrophobicContact CD2-CB 4.16Å; L230-L452 HydrophobicContact CD2-CD1 4.25Å; L230-P454 HydrophobicContact CD2-CB 4.18Å
231D96.1Very high96.6Very high51 Ų5147.8 Ų47.827%0.27323%0.234SC..THydrogen-bonded Turntrans54.638.8177.3-165.431.7000114.1S189 P190 R191 F227 T228 E229S189-D231 WeakPolarHBondContact CA-OD2 3.48Å; S189-D231 VanDerWaalsContact CB-OD2 3.3Å; S189-D231 WeakPolarHBondContact CB-OD2 3.44Å; S189-D231 PolarHBondContact OG-OD2 2.91Å; P190-D231 CarbonylContact C-O 3.55Å; P190-D231 WeakPolarHBondContact CA-O 3.5Å; P190-D231 WeakPolarHBondContact CB-O 3.44Å; R191-D231 PolarHBondContact N-O 2.69Å; F227-D231 PolarHBondContact O-N 2.83Å; T228-D231 WeakPolarHBondContact O-CA 3.37Å; T228-D231 PolarHBondContact O-N 3.07Å; E229-D231 VanDerWaalsContact C-N 3.26Å
232Y97.3Very high96.8Very high7 Ų745.3 Ų45.33%0.02722%0.222CC..EExtended strand (participates in β ladder)trans-94.9140.9164.6-69.4-104.1000109.6M186 R191 G192 A194 F227 L230 V234 S263 V265 M308M186-Y232 WeakPolarHBondContact CE-OH 3.46Å; R191-Y232 HydrophobicContact CB-CE2 4.43Å; G192-Y232 VanDerWaalsContact O-CA 3.31Å; G192-Y232 WeakPolarHBondContact O-CA 3.46Å; A194-Y232 HydrophobicContact CB-CD1 4.26Å; A194-Y232 HydrophobicContact CB-CG 4.33Å; F227-Y232 HydrophobicContact CB-CD2 4.46Å; F227-Y232 HydrophobicContact CB-CG 4.48Å; F227-Y232 HydrophobicContact CD1-CD2 4.34Å; F227-Y232 WeakPolarHBondContact O-CB 3.31Å; F227-Y232 PolarHBondContact O-N 2.97Å; L230-Y232 VanDerWaalsContact C-N 3.29Å; L230-Y232 HydrophobicContact CB-CD2 3.8Å; L230-Y232 HydrophobicContact CB-CE2 3.91Å; L230-Y232 VanDerWaalsContact O-CD2 3.24Å; L230-Y232 WeakPolarHBondContact O-CD2 3.37Å; L230-Y232 WeakPolarHBondContact O-CE2 3.39Å; L230-Y232 PolarHBondContact O-N 3.3Å; Y232-V234 PolarHBondContact O-N 3.48Å; Y232-S263 VanDerWaalsContact CE1-OG 3.23Å; Y232-S263 WeakPolarHBondContact CE1-OG 3.13Å; Y232-S263 PolarHBondContact OH-OG 2.78Å; Y232-V265 HydrophobicContact CD1-CG2 3.98Å; Y232-V265 HydrophobicContact CE1-CG2 3.62Å; Y232-M308 HydrophobicContact CE1-CE 4.18Å; Y232-M308 WeakPolarHBondContact OH-CE 3.37Å
233H97.6Very high96.9Very high105 Ų10549.7 Ų49.749%0.48624%0.242SC..EExtended strand (participates in β ladder)trans-79.9104166.9-175.292.4000109P190 G192 F193 A194P190-H233 HydrophobicContact CB-CB 4.48Å; P190-H233 HydrophobicContact CG-CB 4.45Å; G192-H233 PolarHBondContact O-N 3.09Å; F193-H233 HydrophobicContact CD1-CB 3.75Å; F193-H233 AromaticContact CD1-CD2 3.9Å; F193-H233 HydrophobicContact CE1-CB 3.86Å; F193-H233 AromaticContact CE1-CD2 4Å; A194-H233 PolarHBondContact N-O 3.31Å
234V98.3Very high97Very high28 Ų2850.8 Ų50.817%0.1725%0.253CS..EExtended strand (participates in β ladder)trans-91.4126-172.2-163.90000112.2A194 V196 R224 F227 Y232 V236A194-V234 HydrophobicContact CB-CB 4.35Å; A194-V234 HydrophobicContact CB-CG1 4.1Å; A194-V234 HydrophobicContact CB-CG2 4.11Å; A194-V234 CarbonylContact O-C 3.57Å; A194-V234 WeakPolarHBondContact O-CA 3.48Å; V196-V234 HydrophobicContact CG2-CG1 3.92Å; R224-V234 HydrophobicContact CG-CB 4.35Å; R224-V234 HydrophobicContact CG-CG1 4.27Å; F227-V234 HydrophobicContact CB-CG2 3.77Å; Y232-V234 PolarHBondContact O-N 3.48Å; V234-V236 HydrophobicContact CG1-CG2 4.01Å
235S97.9Very high97Very high26 Ų2646.3 Ų46.318%0.18224%0.236CC..EExtended strand (participates in β ladder)trans-108.7111.5168.253.40000110.1A194 V196A194-S235 PolarHBondContact O-N 3.24Å; A194-S235 PolarHBondContact O-OG 3.19Å; V196-S235 PolarHBondContact N-O 3.2Å
236V98.1Very high97.1Very high43 Ų4344.9 Ų44.926%0.26123%0.228SC..EExtended strand (participates in β ladder)trans-99.6126.8177-172.80000109.7V196 D220 R224 V234 R238V196-V236 HydrophobicContact CB-CG1 4.35Å; V196-V236 HydrophobicContact CB-CG2 4.19Å; V196-V236 HydrophobicContact CG1-CG1 4.4Å; V196-V236 HydrophobicContact CG2-CG2 4.49Å; V196-V236 CarbonylContact O-C 3.57Å; V196-V236 WeakPolarHBondContact O-CA 3.36Å; D220-V236 HydrophobicContact CB-CG1 4.16Å; R224-V236 HydrophobicContact CB-CG2 3.98Å; R224-V236 HydrophobicContact CG-CG2 3.88Å; V234-V236 HydrophobicContact CG1-CG2 4.01Å; V236-R238 HydrophobicContact CG1-CG 4.45Å
237H98.1Very high97.2Very high76 Ų7647.9 Ų47.935%0.35225%0.246SC..EExtended strand (participates in β ladder)trans-121.4134173.2-59.7-93.3000109V196 I197 S198 L240 C248V196-H237 PolarHBondContact O-N 3.5Å; I197-H237 WeakPolarHBondContact CA-O 3.41Å; S198-H237 PolarHBondContact N-O 2.64Å; H237-L240 HydrophobicContact CB-CD1 3.78Å; H237-L240 HydrophobicContact CB-CG 4.17Å; H237-C248 VanDerWaalsContact CD2-SG 3.52Å
238R96.9Very high97.2Very high128 Ų12848.6 Ų48.648%0.48325%0.251SS..EExtended strand (participates in β ladder)trans-113.6153.1179.2-60.5-164.5-177105-3.9112S198 D220 V236 L240S198-R238 WeakPolarHBondContact O-CA 3.26Å; D220-R238 VanDerWaalsContact CG-NE 3.34Å; D220-R238 IonicContact OD1-CZ 3.14Å; D220-R238 VanDerWaalsContact OD1-CZ 3.31Å; D220-R238 IonicContact OD1-NE 2.74Å; D220-R238 PolarHBondContact OD1-NE 3.4Å; D220-R238 IonicContact OD1-NH2 2.71Å; D220-R238 PolarHBondContact OD1-NH2 2.89Å; D220-R238 IonicContact OD2-CZ 3.19Å; D220-R238 IonicContact OD2-NE 3.85Å; D220-R238 PolarHBondContact OD2-NE 2.95Å; D220-R238 IonicContact OD2-NH2 3.93Å; V236-R238 HydrophobicContact CG1-CG 4.45Å; R238-L240 VanDerWaalsContact C-N 3.33Å; R238-L240 PolarHBondContact O-N 3.25Å
239D96.5Very high97.3Very high54 Ų5445.1 Ų45.129%0.28923%0.23SC..SBendtrans51.342.5168.6-63-14.6000115.5S198 N199 V200 T201 T280S198-D239 PolarHBondContact O-N 3.43Å; N199-D239 PolarHBondContact OD1-N 2.78Å; V200-D239 WeakPolarHBondContact CA-OD1 3.39Å; V200-D239 PolarHBondContact N-OD1 2.88Å; T201-D239 WeakPolarHBondContact CB-OD2 3.37Å; T201-D239 PolarHBondContact N-OD1 3.09Å; T201-D239 PolarHBondContact OG1-OD2 2.66Å; D239-T280 VanDerWaalsContact CA-CG2 3.46Å; D239-T280 HydrophobicContact CB-CG2 3.97Å; D239-T280 WeakPolarHBondContact O-CG2 3.31Å; D239-T280 PolarHBondContact O-OG1 2.74Å; D239-T280 VanDerWaalsContact O-OG1 3.04Å
240L97.6Very high97.4Very high35 Ų3545.3 Ų45.318%0.18323%0.231CC..  trans-80.9132.7-179.5-64.2-173.4000112.7I197 N199 H237 R238 M245 C248 G279 T280I197-L240 HydrophobicContact CD1-CD1 4.24Å; I197-L240 HydrophobicContact CG1-CD1 4.41Å; I197-L240 HydrophobicContact CG2-CB 4.47Å; I197-L240 HydrophobicContact CG2-CD1 4.1Å; I197-L240 HydrophobicContact CG2-CG 4.45Å; N199-L240 PolarHBondContact ND2-O 3.18Å; N199-L240 PolarHBondContact OD1-N 3.1Å; H237-L240 HydrophobicContact CB-CD1 3.78Å; H237-L240 HydrophobicContact CB-CG 4.17Å; R238-L240 VanDerWaalsContact C-N 3.33Å; R238-L240 PolarHBondContact O-N 3.25Å; L240-M245 HydrophobicContact CB-CB 4.47Å; L240-M245 HydrophobicContact CB-CG 3.47Å; L240-M245 VanDerWaalsContact CB-CG 3.47Å; L240-M245 HydrophobicContact CD1-CG 4.23Å; L240-C248 HydrophobicContact CD1-CB 3.91Å; L240-G279 WeakPolarHBondContact O-CA 3.3Å; L240-T280 PolarHBondContact O-N 3.2Å; L240-T280 PolarHBondContact O-OG1 2.95Å
241T97.5Very high97.5Very high61 Ų6149.9 Ų49.937%0.37426%0.255SS..  trans-61.5160164.7630000110.5Q243 G244 M245 T280 D281T241-Q243 PolarHBondContact O-N 3.25Å; T241-Q243 VanDerWaalsContact O-N 3.16Å; T241-G244 CarbonylContact O-C 3.47Å; T241-G244 WeakPolarHBondContact O-CA 3.5Å; T241-G244 PolarHBondContact O-N 2.93Å; T241-G244 PolarHBondContact OG1-N 3.2Å; T241-M245 WeakPolarHBondContact O-CG 3.15Å; T241-M245 PolarHBondContact O-N 3.47Å; T241-T280 PolarHBondContact N-OG1 3.06Å; T241-T280 VanDerWaalsContact N-OG1 3.14Å; T241-D281 HydrophobicContact CG2-CB 4Å
242A96.5Very high97.5Very high0 Ų047.8 Ų47.80%024%0.244CC..Hα-helixtrans-59.1-34.3-177.600000112.2R246 D281 Q283 I285A242-R246 WeakPolarHBondContact O-CG 3.47Å; A242-R246 PolarHBondContact O-N 3.41Å; A242-D281 VanDerWaalsContact N-CG 3.33Å; A242-D281 PolarHBondContact N-OD1 3.31Å; A242-D281 PolarHBondContact N-OD2 3.07Å; A242-D281 VanDerWaalsContact N-OD2 3.17Å; A242-Q283 HydrophobicContact CB-CB 3.61Å; A242-I285 HydrophobicContact CB-CD1 4.2Å; A242-I285 HydrophobicContact CB-CG1 3.94Å; A242-I285 WeakPolarHBondContact O-CD1 3.44Å
243Q97.4Very high97.4Very high107 Ų10748 Ų4850%0.525%0.246SC..Hα-helixtrans-73.4-34.7174.2-167.95723.900113T241 T247T241-Q243 PolarHBondContact O-N 3.25Å; T241-Q243 VanDerWaalsContact O-N 3.16Å; Q243-T247 WeakPolarHBondContact O-CB 3.43Å; Q243-T247 PolarHBondContact O-N 3.37Å; Q243-T247 PolarHBondContact O-OG1 3.37Å
244G98.1Very high97.2Very high22 Ų2250.5 Ų50.523%0.22725%0.251CS..Hα-helixtrans-62.7-44.6171.300000112.3T241 T247 C248T241-G244 CarbonylContact O-C 3.47Å; T241-G244 WeakPolarHBondContact O-CA 3.5Å; T241-G244 PolarHBondContact O-N 2.93Å; T241-G244 PolarHBondContact OG1-N 3.2Å; G244-T247 PolarHBondContact O-N 2.92Å; G244-C248 VanDerWaalsContact O-CB 3.27Å; G244-C248 WeakPolarHBondContact O-CB 3.34Å; G244-C248 PolarHBondContact O-N 3.03Å
245M98.1Very high96.9Very high1 Ų151.8 Ų51.81%0.00525%0.253CS..Hα-helixtrans-61.5-46.9175-66.8177.673.500112.1I197 N199 L240 T241 T247 C248 I249 I277 I285I197-M245 HydrophobicContact CD1-CB 4.45Å; I197-M245 HydrophobicContact CG2-CE 4.02Å; I197-M245 HydrophobicContact CG2-CG 4.08Å; N199-M245 PolarHBondContact ND2-SD 3.05Å; N199-M245 VanDerWaalsContact ND2-SD 3.39Å; L240-M245 HydrophobicContact CB-CB 4.47Å; L240-M245 HydrophobicContact CB-CG 3.47Å; L240-M245 VanDerWaalsContact CB-CG 3.47Å; L240-M245 HydrophobicContact CD1-CG 4.23Å; T241-M245 WeakPolarHBondContact O-CG 3.15Å; T241-M245 PolarHBondContact O-N 3.47Å; M245-T247 PolarHBondContact O-N 3.5Å; M245-C248 PolarHBondContact O-N 3.47Å; M245-I249 WeakPolarHBondContact O-CB 3.33Å; M245-I249 WeakPolarHBondContact O-CG1 3.37Å; M245-I249 PolarHBondContact O-N 3.25Å; M245-I277 HydrophobicContact CE-CD1 3.58Å; M245-I277 HydrophobicContact CE-CG1 4.16Å; M245-I285 HydrophobicContact CB-CD1 3.41Å; M245-I285 VanDerWaalsContact CB-CD1 3.41Å; M245-I285 HydrophobicContact CE-CD1 4.13Å; M245-I285 HydrophobicContact CG-CD1 4.23Å; M245-I285 HydrophobicContact SD-CD1 3.88Å
246R97.6Very high96.7Very high69 Ų6955.1 Ų55.126%0.2627%0.274SS..Hα-helixtrans-55.8-50.5175.2-76-177.5-174.394.211111.3A242 C248 I249 E250 L284 I285 W289A242-R246 WeakPolarHBondContact O-CG 3.47Å; A242-R246 PolarHBondContact O-N 3.41Å; R246-C248 VanDerWaalsContact C-N 3.32Å; R246-C248 PolarHBondContact O-N 2.74Å; R246-I249 PolarHBondContact O-N 3.05Å; R246-E250 WeakPolarHBondContact O-CB 3.46Å; R246-E250 WeakPolarHBondContact O-CG 3.34Å; R246-E250 PolarHBondContact O-N 2.79Å; R246-L284 PolarHBondContact NH2-O 2.89Å; R246-I285 HydrophobicContact CG-CD1 4.16Å; R246-I285 HydrophobicContact CG-CG1 4.49Å; R246-W289 HydrophobicContact CB-CH2 3.82Å; R246-W289 HydrophobicContact CB-CZ2 4.32Å; R246-W289 HydrophobicContact CB-CZ3 4.39Å; R246-W289 HydrophobicContact CG-CH2 3.73Å; R246-W289 HydrophobicContact CG-CZ2 4.15Å; R246-W289 HydrophobicContact CG-CZ3 3.91Å
247T98Very high96.5Very high63 Ų6356.3 Ų56.339%0.38728%0.277SS..Hα-helixtrans-60.9-40.7179.4-52.30000111.8Q243 G244 M245 N251Q243-T247 WeakPolarHBondContact O-CB 3.43Å; Q243-T247 PolarHBondContact O-N 3.37Å; Q243-T247 PolarHBondContact O-OG1 3.37Å; G244-T247 PolarHBondContact O-N 2.92Å; M245-T247 PolarHBondContact O-N 3.5Å; T247-N251 VanDerWaalsContact O-CB 3.29Å; T247-N251 WeakPolarHBondContact O-CB 3.42Å; T247-N251 PolarHBondContact O-N 3.43Å; T247-N251 PolarHBondContact O-ND2 2.89Å
248C97.9Very high96.3Very high17 Ų1752.7 Ų52.712%0.11526%0.26CS..Hα-helixtrans-64.1-47.1176.9-175.80000112I197 H237 L240 G244 M245 R246 N251 F252I197-C248 HydrophobicContact CD1-CB 4.27Å; H237-C248 VanDerWaalsContact CD2-SG 3.52Å; L240-C248 HydrophobicContact CD1-CB 3.91Å; G244-C248 VanDerWaalsContact O-CB 3.27Å; G244-C248 WeakPolarHBondContact O-CB 3.34Å; G244-C248 PolarHBondContact O-N 3.03Å; M245-C248 PolarHBondContact O-N 3.47Å; R246-C248 VanDerWaalsContact C-N 3.32Å; R246-C248 PolarHBondContact O-N 2.74Å; C248-N251 PolarHBondContact O-N 2.94Å; C248-F252 WeakPolarHBondContact O-CB 3.39Å; C248-F252 PolarHBondContact O-N 2.84Å
249I97.9Very high96Very high0 Ų056 Ų560%027%0.273CS..Hα-helixtrans-63.6-48.8177.5-70.1165.6000110.6L195 I197 M245 R246 N251 F252 C253 L268 W289 V290 A293 F294L195-I249 HydrophobicContact CD2-CG1 4.06Å; I197-I249 HydrophobicContact CD1-CD1 4.28Å; I197-I249 HydrophobicContact CD1-CG1 4.01Å; M245-I249 WeakPolarHBondContact O-CB 3.33Å; M245-I249 WeakPolarHBondContact O-CG1 3.37Å; M245-I249 PolarHBondContact O-N 3.25Å; R246-I249 PolarHBondContact O-N 3.05Å; I249-N251 PolarHBondContact O-N 2.85Å; I249-F252 WeakPolarHBondContact O-CB 3.43Å; I249-F252 PolarHBondContact O-N 2.89Å; I249-F252 VanDerWaalsContact O-N 3.12Å; I249-C253 PolarHBondContact O-N 2.84Å; I249-C253 PolarHBondContact O-SG 3.48Å; I249-L268 HydrophobicContact CD1-CD2 4.49Å; I249-W289 HydrophobicContact CB-CH2 4.28Å; I249-W289 HydrophobicContact CB-CZ3 4.34Å; I249-W289 HydrophobicContact CD1-CZ3 4.15Å; I249-W289 HydrophobicContact CG2-CH2 4.13Å; I249-W289 HydrophobicContact CG2-CZ3 4.12Å; I249-V290 HydrophobicContact CD1-CG1 4.31Å; I249-V290 HydrophobicContact CD1-CG2 4.09Å; I249-A293 HydrophobicContact CG2-CB 4.41Å; I249-F294 HydrophobicContact CG2-CE2 3.91Å; I249-F294 HydrophobicContact CG2-CZ 4.42Å
250E96.5Very high95.8Very high58 Ų5858.7 Ų58.727%0.27129%0.291SS..Hα-helixtrans-58.3-44.7177.5-80.7-173.8-133.100112.8R246 F252 C253 R254 W289R246-E250 WeakPolarHBondContact O-CB 3.46Å; R246-E250 WeakPolarHBondContact O-CG 3.34Å; R246-E250 PolarHBondContact O-N 2.79Å; E250-F252 VanDerWaalsContact C-N 3.31Å; E250-F252 PolarHBondContact O-N 2.67Å; E250-C253 PolarHBondContact O-N 3.44Å; E250-R254 WeakPolarHBondContact O-CB 3.47Å; E250-R254 VanDerWaalsContact O-CG 3.27Å; E250-R254 WeakPolarHBondContact O-CG 3.47Å; E250-R254 PolarHBondContact O-N 2.85Å; E250-R254 VanDerWaalsContact O-N 3.11Å; E250-R254 IonicContact OE2-CZ 3.29Å; E250-R254 IonicContact OE2-NH1 2.71Å; E250-R254 PolarHBondContact OE2-NH1 3.17Å; E250-R254 IonicContact OE2-NH2 3.41Å; E250-R254 PolarHBondContact OE2-NH2 3.34Å; E250-W289 HydrophobicContact CG-CH2 4.31Å; E250-W289 HydrophobicContact CG-CZ2 4.1Å
251N97.2Very high95.7Very high97 Ų9757.2 Ų57.252%0.51928%0.283SS..Hα-helixtrans-64.8-37.2176.7-73.5-18.2000111.6T247 C248 I249 R254T247-N251 VanDerWaalsContact O-CB 3.29Å; T247-N251 WeakPolarHBondContact O-CB 3.42Å; T247-N251 PolarHBondContact O-N 3.43Å; T247-N251 PolarHBondContact O-ND2 2.89Å; C248-N251 PolarHBondContact O-N 2.94Å; I249-N251 PolarHBondContact O-N 2.85Å; N251-R254 PolarHBondContact O-N 2.84Å
252F97.5Very high95.5Very high7 Ų755 Ų553%0.03127%0.269CS..Hα-helixtrans-67-44175-174.4-88.9000111.9F193 L195 C248 I249 E250 R254 R255 H258 C264 V266 F294F193-F252 HydrophobicContact CB-CE2 3.65Å; F193-F252 HydrophobicContact CB-CZ 3.67Å; L195-F252 HydrophobicContact CB-CD1 4.34Å; L195-F252 HydrophobicContact CB-CD2 3.75Å; L195-F252 HydrophobicContact CB-CE1 4.24Å; L195-F252 HydrophobicContact CB-CE2 3.64Å; L195-F252 HydrophobicContact CB-CG 4.09Å; L195-F252 HydrophobicContact CB-CZ 3.89Å; L195-F252 HydrophobicContact CD2-CB 3.99Å; L195-F252 HydrophobicContact CD2-CD1 4.37Å; L195-F252 HydrophobicContact CD2-CD2 4.34Å; L195-F252 HydrophobicContact CD2-CG 4Å; L195-F252 HydrophobicContact CG-CD2 4.46Å; C248-F252 WeakPolarHBondContact O-CB 3.39Å; C248-F252 PolarHBondContact O-N 2.84Å; I249-F252 WeakPolarHBondContact O-CB 3.43Å; I249-F252 PolarHBondContact O-N 2.89Å; I249-F252 VanDerWaalsContact O-N 3.12Å; E250-F252 VanDerWaalsContact C-N 3.31Å; E250-F252 PolarHBondContact O-N 2.67Å; F252-R254 VanDerWaalsContact C-N 3.26Å; F252-R254 PolarHBondContact O-N 3.07Å; F252-R255 WeakPolarHBondContact O-CG 3.35Å; F252-R255 PolarHBondContact O-N 3.22Å; F252-H258 AromaticContact CE1-CE1 3.83Å; F252-H258 AromaticContact CE1-NE2 3.98Å; F252-H258 PolarHBondContact O-CD2 2.94Å; F252-H258 PolarHBondContact O-NE2 3.2Å; F252-C264 HydrophobicContact CE1-CB 4.17Å; F252-C264 HydrophobicContact CZ-CB 4.35Å; F252-V266 HydrophobicContact CE1-CG2 4.19Å; F252-F294 AromaticContact CD1-CE1 3.66Å; F252-F294 HydrophobicContact CD1-CE1 3.66Å; F252-F294 AromaticContact CD1-CZ 3.67Å; F252-F294 HydrophobicContact CD1-CZ 3.67Å; F252-F294 AromaticContact CE1-CE1 3.83Å; F252-F294 HydrophobicContact CE1-CE1 3.83Å; F252-F294 HydrophobicContact CE1-CZ 4.07Å
253C93.9Very high95.5Very high10 Ų1055 Ų557%0.06827%0.269CS..Hα-helixtrans-61.4-32.9176.3-64.60000113I249 E250 A293 F294 C299I249-C253 PolarHBondContact O-N 2.84Å; I249-C253 PolarHBondContact O-SG 3.48Å; E250-C253 PolarHBondContact O-N 3.44Å; C253-A293 PolarHBondContact SG-O 2.77Å; C253-F294 WeakPolarHBondContact SG-CE1 3.28Å; C253-F294 WeakPolarHBondContact SG-CZ 3.47Å; C253-C299 PolarHBondContact O-SG 2.97Å
254R92.9Very high95.5Very high159 Ų15949.9 Ų49.960%0.625%0.245SC*.THydrogen-bonded Turntrans-84.5-0.2-176.7-69.6173.2-174.7137.410.5114.6E250 N251 F252 P256E250-R254 WeakPolarHBondContact O-CB 3.47Å; E250-R254 VanDerWaalsContact O-CG 3.27Å; E250-R254 WeakPolarHBondContact O-CG 3.47Å; E250-R254 PolarHBondContact O-N 2.85Å; E250-R254 VanDerWaalsContact O-N 3.11Å; E250-R254 IonicContact OE2-CZ 3.29Å; E250-R254 IonicContact OE2-NH1 2.71Å; E250-R254 PolarHBondContact OE2-NH1 3.17Å; E250-R254 IonicContact OE2-NH2 3.41Å; E250-R254 PolarHBondContact OE2-NH2 3.34Å; N251-R254 PolarHBondContact O-N 2.84Å; F252-R254 VanDerWaalsContact C-N 3.26Å; F252-R254 PolarHBondContact O-N 3.07Å; R254-P256 WeakPolarHBondContact O-CD 3.26Å
255R93.9Very high95.5Very high54 Ų5448.8 Ų48.820%0.20423%0.234CC..  trans-60.6117.6-178.5-75.3-170.477.9160.44.8112.4F252 E257 H258 L301F252-R255 WeakPolarHBondContact O-CG 3.35Å; F252-R255 PolarHBondContact O-N 3.22Å; R255-E257 WeakPolarHBondContact CB-OE2 3.48Å; R255-E257 IonicContact CZ-OE1 2.78Å; R255-E257 VanDerWaalsContact CZ-OE1 3.27Å; R255-E257 IonicContact NE-OE1 3.17Å; R255-E257 PolarHBondContact NE-OE1 2.75Å; R255-E257 IonicContact NE-OE2 3.21Å; R255-E257 IonicContact NH2-OE1 2.73Å; R255-E257 PolarHBondContact NH2-OE1 2.98Å; R255-E257 PolarHBondContact O-N 2.85Å; R255-H258 WeakPolarHBondContact O-CB 3.33Å; R255-H258 PolarHBondContact O-CD2 3.21Å; R255-H258 PolarHBondContact O-N 2.91Å; R255-L301 WeakPolarHBondContact O-CD1 3.4Å
256P93.1Very high95.5Very high96 Ų9648.8 Ų48.862%0.62323%0.234SC*.G310 helixtrans-61.9-24.5177.625.3-35.2000113.4R254 H258 R259R254-P256 WeakPolarHBondContact O-CD 3.26Å; P256-H258 PolarHBondContact O-N 3.16Å; P256-R259 VanDerWaalsContact O-CB 3.26Å; P256-R259 WeakPolarHBondContact O-CB 3.35Å; P256-R259 PolarHBondContact O-N 2.72Å; P256-R259 VanDerWaalsContact O-N 3.1Å
257E93.8Very high95.6Very high69 Ų6945.5 Ų45.532%0.32222%0.222SC..G310 helixtrans-66.8-17.5178.8-46.397.9110.600113F193 R255 R259 T260 V261F193-E257 HydrophobicContact CE2-CB 3.48Å; F193-E257 VanDerWaalsContact CE2-CB 3.48Å; F193-E257 HydrophobicContact CZ-CB 3.47Å; F193-E257 VanDerWaalsContact CZ-CB 3.47Å; F193-E257 HydrophobicContact CZ-CG 4.25Å; R255-E257 WeakPolarHBondContact CB-OE2 3.48Å; R255-E257 IonicContact CZ-OE1 2.78Å; R255-E257 VanDerWaalsContact CZ-OE1 3.27Å; R255-E257 IonicContact NE-OE1 3.17Å; R255-E257 PolarHBondContact NE-OE1 2.75Å; R255-E257 IonicContact NE-OE2 3.21Å; R255-E257 IonicContact NH2-OE1 2.73Å; R255-E257 PolarHBondContact NH2-OE1 2.98Å; R255-E257 PolarHBondContact O-N 2.85Å; E257-R259 PolarHBondContact O-N 2.78Å; E257-T260 PolarHBondContact O-N 2.87Å; E257-T260 PolarHBondContact O-OG1 2.84Å; E257-V261 PolarHBondContact O-N 3.4Å
258H93.2Very high95.5Very high0 Ų042.5 Ų42.50%020%0.203CC..G310 helixtrans-56.5-20169-76.2-39.5000112.7F193 F252 R255 P256 L301 L302 K305F193-H258 AromaticContact CD2-CE1 3.95Å; F193-H258 AromaticContact CD2-ND1 3.67Å; F252-H258 AromaticContact CE1-CE1 3.83Å; F252-H258 AromaticContact CE1-NE2 3.98Å; F252-H258 PolarHBondContact O-CD2 2.94Å; F252-H258 PolarHBondContact O-NE2 3.2Å; R255-H258 WeakPolarHBondContact O-CB 3.33Å; R255-H258 PolarHBondContact O-CD2 3.21Å; R255-H258 PolarHBondContact O-N 2.91Å; P256-H258 PolarHBondContact O-N 3.16Å; H258-L301 HydrophobicContact CB-CB 3.69Å; H258-L301 HydrophobicContact CB-CD1 4.25Å; H258-L302 HydrophobicContact CB-CD2 3.83Å; H258-L302 HydrophobicContact CB-CG 4.1Å; H258-K305 PolarHBondContact O-NZ 3.22Å
259R91.3Very high95.4Very high198 Ų19841.8 Ų41.875%0.74720%0.198SC*.G310 helixtrans-61.7-40.5172.9-173.3175.3177.8174.4-0.9112.5P256 E257 L301 K305P256-R259 VanDerWaalsContact O-CB 3.26Å; P256-R259 WeakPolarHBondContact O-CB 3.35Å; P256-R259 PolarHBondContact O-N 2.72Å; P256-R259 VanDerWaalsContact O-N 3.1Å; E257-R259 PolarHBondContact O-N 2.78Å; R259-L301 HydrophobicContact CB-CD2 4.32Å; R259-K305 PolarHBondContact O-NZ 3.37Å
260T92Very high95.2Very high110 Ų11041.9 Ų41.968%0.67520%0.199SC*.THydrogen-bonded Turntrans-96.5-20.2-167.644.30000115.1E257E257-T260 PolarHBondContact O-N 2.87Å; E257-T260 PolarHBondContact O-OG1 2.84Å
261V94.6Very high94.7Very high4 Ų441 Ų412%0.02420%0.195CC..SBendtrans-90.3161.7173.1-55.50000111.3P190 F193 E257 K305P190-V261 HydrophobicContact CG-CG1 4.1Å; P190-V261 WeakPolarHBondContact O-CG1 3.42Å; F193-V261 HydrophobicContact CD2-CG1 4.19Å; F193-V261 HydrophobicContact CD2-CG2 3.86Å; F193-V261 HydrophobicContact CE2-CB 4.46Å; F193-V261 HydrophobicContact CE2-CG1 3.63Å; F193-V261 HydrophobicContact CE2-CG2 3.93Å; F193-V261 HydrophobicContact CZ-CG1 4.21Å; E257-V261 PolarHBondContact O-N 3.4Å; V261-K305 WeakPolarHBondContact O-CE 3.41Å; V261-K305 PolarHBondContact O-NZ 3.2Å
262D94.9Very high94.2Very high13 Ų1336.8 Ų36.87%0.0717%0.174CC..SBendtrans-91.1-17.3-177.2-71.9-50.2000114.4R185 M186 N187 S188 R191 K305 P306R185-D262 WeakPolarHBondContact CD-OD1 3.39Å; R185-D262 WeakPolarHBondContact CG-OD1 3.36Å; R185-D262 IonicContact NE-OD1 3.77Å; R185-D262 PolarHBondContact NE-OD1 3.18Å; R185-D262 IonicContact NE-OD2 3.85Å; R185-D262 WeakPolarHBondContact O-CB 3.27Å; M186-D262 HydrophobicContact SD-CB 4.09Å; N187-D262 PolarHBondContact N-OD2 3.48Å; S188-D262 WeakPolarHBondContact CB-OD2 3.44Å; S188-D262 PolarHBondContact N-OD2 3.32Å; S188-D262 WeakPolarHBondContact OG-CB 3.5Å; S188-D262 PolarHBondContact OG-N 2.82Å; S188-D262 PolarHBondContact OG-OD2 3.17Å; R191-D262 PolarHBondContact O-N 3.03Å; D262-K305 VanDerWaalsContact O-CB 3.27Å; D262-K305 WeakPolarHBondContact O-CB 3.37Å; D262-K305 WeakPolarHBondContact O-CG 3.27Å; D262-P306 WeakPolarHBondContact O-CD 3.44Å
263S96.3Very high93.4Very high0 Ų038.6 Ų38.60%019%0.186CC..EExtended strand (participates in β ladder)trans-151.9171.2-170.166.20000114.3R191 G192 Y232R191-S263 PolarHBondContact O-N 2.87Å; R191-S263 VanDerWaalsContact O-N 3.13Å; R191-S263 PolarHBondContact O-OG 2.99Å; G192-S263 WeakPolarHBondContact CA-O 3.49Å; Y232-S263 VanDerWaalsContact CE1-OG 3.23Å; Y232-S263 WeakPolarHBondContact CE1-OG 3.13Å; Y232-S263 PolarHBondContact OH-OG 2.78Å
264C97.1Very high92.7Very high0 Ų043 Ų430%021%0.205CC..EExtended strand (participates in β ladder)trans-138.9154.4163.378.90000113.2F193 F252 L302 P306 M308F193-C264 WeakPolarHBondContact O-CA 3.15Å; F252-C264 HydrophobicContact CE1-CB 4.17Å; F252-C264 HydrophobicContact CZ-CB 4.35Å; C264-L302 HydrophobicContact CB-CD1 4Å; C264-L302 VanDerWaalsContact SG-CD1 3.58Å; C264-P306 PolarHBondContact N-O 2.83Å; C264-M308 PolarHBondContact O-N 2.88Å
265V98.3Very high92.1Very high0 Ų036.7 Ų36.70%019%0.19CC..EExtended strand (participates in β ladder)trans-120140.7171177.40000109.7F193 A194 L195 F227 Y232 M308 F310F193-V265 PolarHBondContact O-N 3.35Å; A194-V265 CarbonylContact C-O 3.04Å; A194-V265 WeakPolarHBondContact CA-O 3.49Å; A194-V265 HydrophobicContact CB-CB 3.9Å; A194-V265 HydrophobicContact CB-CG1 4.45Å; L195-V265 PolarHBondContact N-O 3.07Å; F227-V265 HydrophobicContact CD1-CG2 4.26Å; F227-V265 HydrophobicContact CD2-CG1 4.28Å; F227-V265 HydrophobicContact CE1-CG1 4.13Å; F227-V265 HydrophobicContact CE1-CG2 4.06Å; F227-V265 HydrophobicContact CE2-CG1 3.75Å; F227-V265 HydrophobicContact CZ-CG1 3.7Å; F227-V265 HydrophobicContact CZ-CG2 4.46Å; Y232-V265 HydrophobicContact CD1-CG2 3.98Å; Y232-V265 HydrophobicContact CE1-CG2 3.62Å; V265-M308 CarbonylContact C-O 3.52Å; V265-M308 WeakPolarHBondContact CA-O 3.29Å; V265-M308 HydrophobicContact CG2-CB 4.19Å; V265-M308 HydrophobicContact CG2-CE 3.64Å; V265-M308 HydrophobicContact CG2-SD 4.21Å; V265-F310 HydrophobicContact CG1-CD2 3.82Å; V265-F310 HydrophobicContact CG1-CE2 3.83Å
266V98.2Very high91.7Very high0 Ų034.2 Ų34.20%018%0.181CC..EExtended strand (participates in β ladder)trans-134.8106.8174.7-176.40000109L195 F252 L268 F294 M308 F309 F310L195-V266 HydrophobicContact CD2-CG1 4.39Å; L195-V266 CarbonylContact O-C 3.46Å; L195-V266 WeakPolarHBondContact O-CA 3.49Å; F252-V266 HydrophobicContact CE1-CG2 4.19Å; V266-L268 HydrophobicContact CG1-CD1 4.39Å; V266-L268 HydrophobicContact CG1-CD2 4Å; V266-L268 HydrophobicContact CG1-CG 4.08Å; V266-F294 HydrophobicContact CG1-CE2 4.39Å; V266-F294 HydrophobicContact CG2-CE1 3.86Å; V266-F294 HydrophobicContact CG2-CE2 3.74Å; V266-F294 HydrophobicContact CG2-CZ 3.36Å; V266-M308 PolarHBondContact N-O 2.87Å; V266-F309 HydrophobicContact CB-CD1 3.71Å; V266-F309 HydrophobicContact CB-CE1 3.9Å; V266-F309 HydrophobicContact CG1-CD1 4.13Å; V266-F309 HydrophobicContact CG1-CE1 4.29Å; V266-F309 HydrophobicContact CG2-CD1 4.28Å; V266-F309 HydrophobicContact CG2-CE1 3.97Å; V266-F309 VanDerWaalsContact O-CA 3.3Å; V266-F309 WeakPolarHBondContact O-CA 3.37Å; V266-F310 PolarHBondContact O-N 3.05Å
267S98.3Very high91.7Very high0 Ų029.7 Ų29.70%015%0.152CC..EExtended strand (participates in β ladder)trans-106.5122.8178-52.60000110L195 V196 I197 F310L195-S267 PolarHBondContact O-N 2.7Å; V196-S267 WeakPolarHBondContact CA-O 3.35Å; I197-S267 PolarHBondContact N-O 3.48Å; S267-F310 CarbonylContact C-O 3.25Å; S267-F310 VanDerWaalsContact CA-O 3.3Å; S267-F310 WeakPolarHBondContact CA-O 3.47Å
268L97.2Very high91.6Very high1 Ų129 Ų291%0.00515%0.146CC..EExtended strand (participates in β ladder)trans-120.5109.7-176.8-56.1179.4000108.7I197 I249 V266 I277 L287 V290 F310 I311 Q312I197-L268 HydrophobicContact CB-CD2 3.89Å; I197-L268 HydrophobicContact CD1-CD2 3.92Å; I197-L268 HydrophobicContact CG1-CD2 4.06Å; I249-L268 HydrophobicContact CD1-CD2 4.49Å; V266-L268 HydrophobicContact CG1-CD1 4.39Å; V266-L268 HydrophobicContact CG1-CD2 4Å; V266-L268 HydrophobicContact CG1-CG 4.08Å; L268-I277 HydrophobicContact CB-CD1 3.92Å; L268-I277 HydrophobicContact CD1-CD1 3.66Å; L268-I277 HydrophobicContact CG-CD1 4.3Å; L268-L287 HydrophobicContact CD1-CD2 4.36Å; L268-V290 HydrophobicContact CD1-CG1 4.13Å; L268-V290 HydrophobicContact CD1-CG2 4.39Å; L268-F310 PolarHBondContact N-O 3.35Å; L268-I311 HydrophobicContact CB-CD1 3.97Å; L268-I311 HydrophobicContact CD1-CD1 3.92Å; L268-I311 HydrophobicContact CG-CD1 4.08Å; L268-Q312 PolarHBondContact O-N 3.42Å
269L96Very high91.7Very high1 Ų129 Ų291%0.00515%0.146CC..EExtended strand (participates in β ladder)trans-115.2105.3-175-33.5176.1000108.8V196 I197 N199 R213 D219 D220 L223 Q312 I394V196-L269 HydrophobicContact CG1-CD1 4.3Å; I197-L269 PolarHBondContact O-N 3.13Å; N199-L269 PolarHBondContact N-O 3.02Å; R213-L269 PolarHBondContact NH1-O 3.3Å; D219-L269 HydrophobicContact CB-CD1 3.8Å; D220-L269 HydrophobicContact CB-CD1 4.04Å; L223-L269 HydrophobicContact CD1-CD1 4.13Å; L223-L269 HydrophobicContact CD1-CD2 3.95Å; L269-Q312 WeakPolarHBondContact CA-O 3.48Å; L269-Q312 HydrophobicContact CB-CB 4.25Å; L269-Q312 HydrophobicContact CD2-CB 3.54Å; L269-Q312 HydrophobicContact CD2-CG 4.49Å; L269-Q312 HydrophobicContact CG-CB 4.49Å; L269-I394 HydrophobicContact CD2-CD1 3.99Å; L269-I394 HydrophobicContact CD2-CG1 4.42Å
270S92.8Very high91.8Very high3 Ų320.2 Ų20.22%0.02112%0.115CC..SBendtrans-154.1-171.5-178.3-163.80000111.4N199 F202 R213 Y278 Q312N199-S270 WeakPolarHBondContact CB-OG 3.5Å; F202-S270 WeakPolarHBondContact CZ-OG 3.5Å; R213-S270 PolarHBondContact NE-O 3.24Å; R213-S270 PolarHBondContact NH2-O 2.96Å; S270-Y278 PolarHBondContact OG-O 3.03Å; S270-Q312 PolarHBondContact N-O 2.78Å
271H87.1Confident91.9Very high40 Ų4016.6 Ų16.619%0.1859%0.091CC..  trans-75.8161.1153.8-71.1-59.2000109.8F202 L210 D211 R213 Y278F202-H271 AromaticContact CD2-CD2 3.91Å; F202-H271 AromaticContact CE1-CD2 3.95Å; F202-H271 AromaticContact CE2-CD2 3.48Å; F202-H271 VanDerWaalsContact CE2-CD2 3.48Å; F202-H271 WeakPolarHBondContact CE2-CD2 3.49Å; F202-H271 AromaticContact CE2-NE2 4Å; F202-H271 HydrophobicContact CZ-CB 4.4Å; F202-H271 AromaticContact CZ-CD2 3.51Å; L210-H271 HydrophobicContact CD1-CB 4.48Å; L210-H271 HydrophobicContact CD2-CB 4.04Å; D211-H271 PolarHBondContact O-NE2 3.49Å; R213-H271 WeakPolarHBondContact CG-NE2 3.21Å; H271-Y278 HydrophobicContact CB-CD2 3.73Å; H271-Y278 HydrophobicContact CB-CG 4.43Å; H271-Y278 PolarHBondContact O-N 3.39Å
272G85.6Confident91.7Very high8 Ų817.2 Ų17.28%0.08210%0.098CC..EExtended strand (participates in β ladder)trans-165.6179.7176.500000113.4A276 C314G272-A276 CarbonylContact C-O 3.6Å; G272-A276 WeakPolarHBondContact CA-O 3.43Å; G272-C314 CarbonylContact C-O 3.49Å; G272-C314 WeakPolarHBondContact CA-O 3.42Å
273V80.8Confident91.6Very high44 Ų4421.9 Ų21.927%0.26712%0.12SC..EExtended strand (participates in β ladder)trans-137.8178.5175-64.90000108G275 A276 Y278 L284 C314V273-G275 PolarHBondContact O-N 2.98Å; V273-G275 VanDerWaalsContact O-N 3.09Å; V273-A276 HydrophobicContact CG2-CB 3.93Å; V273-A276 PolarHBondContact N-O 3.04Å; V273-A276 PolarHBondContact O-N 2.86Å; V273-A276 VanDerWaalsContact O-N 3.14Å; V273-Y278 HydrophobicContact CG1-CE2 4.05Å; V273-L284 HydrophobicContact CG2-CD1 4.07Å; V273-L284 HydrophobicContact CG2-CD2 4.17Å; V273-C314 PolarHBondContact N-O 3.01Å
274E79.7Confident91.3Very high103 Ų10324.6 Ų24.648%0.48113%0.134SC..THydrogen-bonded Turntrans-57.9124.3179.8-150.8-161.4153.500111.1A276 R315 K379E274-A276 VanDerWaalsContact C-N 3.26Å; E274-A276 PolarHBondContact O-N 2.92Å; E274-R315 WeakPolarHBondContact CA-O 3.09Å; E274-R315 VanDerWaalsContact CB-O 3.31Å; E274-R315 WeakPolarHBondContact CB-O 3.39Å; E274-R315 PolarHBondContact N-O 2.85Å; E274-K379 HydrophobicContact CG-CB 4.41Å; E274-K379 HydrophobicContact CG-CG 4.32Å; E274-K379 WeakPolarHBondContact OE1-CG 3.36Å; E274-K379 IonicContact OE1-NZ 2.69Å; E274-K379 PolarHBondContact OE1-NZ 2.82Å
275G80.3Confident91.1Very high27 Ų2724.6 Ų24.628%0.27813%0.134SC..THydrogen-bonded Turntrans76.1-5.2178.900000116.3V273 L287V273-G275 PolarHBondContact O-N 2.98Å; V273-G275 VanDerWaalsContact O-N 3.09Å; G275-L287 WeakPolarHBondContact O-CB 3.35Å; G275-L287 WeakPolarHBondContact O-CG 3.3Å; G275-L287 PolarHBondContact O-N 2.95Å
276A86.1Confident90.8Very high2 Ų229.5 Ų29.52%0.01716%0.157CC..EExtended strand (participates in β ladder)trans-143.6153-172.800000114.7G272 V273 E274 L284 I285G272-A276 CarbonylContact C-O 3.6Å; G272-A276 WeakPolarHBondContact CA-O 3.43Å; V273-A276 HydrophobicContact CG2-CB 3.93Å; V273-A276 PolarHBondContact N-O 3.04Å; V273-A276 PolarHBondContact O-N 2.86Å; V273-A276 VanDerWaalsContact O-N 3.14Å; E274-A276 VanDerWaalsContact C-N 3.26Å; E274-A276 PolarHBondContact O-N 2.92Å; A276-L284 HydrophobicContact CB-CB 4.37Å; A276-L284 HydrophobicContact CB-CD1 4.34Å; A276-L284 HydrophobicContact CB-CD2 3.97Å; A276-L284 HydrophobicContact CB-CG 4.47Å; A276-I285 CarbonylContact C-O 3.46Å; A276-I285 VanDerWaalsContact CA-O 3.23Å; A276-I285 WeakPolarHBondContact CA-O 3.29Å; A276-I285 WeakPolarHBondContact CB-O 3.35Å
277I91.4Very high90.4Very high1 Ų129.9 Ų29.91%0.00516%0.159CC..EExtended strand (participates in β ladder)trans-124.1149.6178.961.3179000111.6M245 L268 L284 I285 L287 I311 A313M245-I277 HydrophobicContact CE-CD1 3.58Å; M245-I277 HydrophobicContact CE-CG1 4.16Å; L268-I277 HydrophobicContact CB-CD1 3.92Å; L268-I277 HydrophobicContact CD1-CD1 3.66Å; L268-I277 HydrophobicContact CG-CD1 4.3Å; I277-L284 WeakPolarHBondContact O-CA 3.43Å; I277-I285 HydrophobicContact CG1-CB 4.22Å; I277-I285 PolarHBondContact N-O 3.01Å; I277-I285 PolarHBondContact O-N 3.42Å; I277-L287 HydrophobicContact CD1-CD2 4.16Å; I277-L287 HydrophobicContact CG1-CD2 4.39Å; I277-L287 HydrophobicContact CG2-CD1 4.43Å; I277-L287 HydrophobicContact CG2-CD2 4Å; I277-L287 HydrophobicContact CG2-CG 4.37Å; I277-I311 HydrophobicContact CG2-CG2 4.42Å; I277-A313 HydrophobicContact CG2-CB 3.77Å
278Y92.7Very high90Very high54 Ų5434.1 Ų34.121%0.21218%0.182CC..EExtended strand (participates in β ladder)trans-87.8137.4-179.3-73.2-77000112.9N199 L210 S270 H271 V273 G282 Q283 L284N199-Y278 PolarHBondContact ND2-O 3.06Å; L210-Y278 HydrophobicContact CD1-CD1 3.87Å; L210-Y278 HydrophobicContact CD1-CD2 4.05Å; L210-Y278 HydrophobicContact CD1-CE1 4.45Å; L210-Y278 HydrophobicContact CD1-CG 3.64Å; L210-Y278 HydrophobicContact CD2-CD2 4.12Å; L210-Y278 HydrophobicContact CD2-CE2 4.12Å; S270-Y278 PolarHBondContact OG-O 3.03Å; H271-Y278 HydrophobicContact CB-CD2 3.73Å; H271-Y278 HydrophobicContact CB-CG 4.43Å; H271-Y278 PolarHBondContact O-N 3.39Å; V273-Y278 HydrophobicContact CG1-CE2 4.05Å; Y278-G282 WeakPolarHBondContact CD1-O 3.33Å; Y278-G282 WeakPolarHBondContact CE1-O 3.14Å; Y278-Q283 WeakPolarHBondContact CA-O 3.13Å; Y278-L284 HydrophobicContact CD1-CD2 3.48Å; Y278-L284 VanDerWaalsContact CD1-CD2 3.48Å; Y278-L284 HydrophobicContact CD1-CG 3.98Å; Y278-L284 HydrophobicContact CD2-CD2 3.94Å; Y278-L284 HydrophobicContact CE1-CD1 4.4Å; Y278-L284 HydrophobicContact CE1-CD2 3.48Å; Y278-L284 VanDerWaalsContact CE1-CD2 3.48Å; Y278-L284 HydrophobicContact CE1-CG 3.74Å; Y278-L284 HydrophobicContact CE2-CD2 3.93Å; Y278-L284 HydrophobicContact CG-CD2 3.73Å
279G95.1Very high89.8Confident0 Ų037.5 Ų37.50%020%0.195CC..  trans-75.5167.7155.200000111.8L240 D281 G282 Q283L240-G279 WeakPolarHBondContact O-CA 3.3Å; G279-D281 WeakPolarHBondContact CA-OD1 3.2Å; G279-D281 PolarHBondContact O-N 3.01Å; G279-G282 PolarHBondContact O-N 2.66Å; G279-G282 VanDerWaalsContact O-N 3.07Å; G279-Q283 PolarHBondContact N-O 3.45Å
280T93.8Very high89.7Confident14 Ų1437.5 Ų37.59%0.08619%0.194CC..THydrogen-bonded Turntrans-67.8-13.1177.555.30000114.5N199 T201 F202 D203 D239 L240 T241 G282N199-T280 HydrophobicContact CB-CG2 3.96Å; T201-T280 WeakPolarHBondContact O-CG2 3.48Å; F202-T280 HydrophobicContact CD1-CG2 4.49Å; D203-T280 PolarHBondContact N-O 3.27Å; D239-T280 VanDerWaalsContact CA-CG2 3.46Å; D239-T280 HydrophobicContact CB-CG2 3.97Å; D239-T280 WeakPolarHBondContact O-CG2 3.31Å; D239-T280 PolarHBondContact O-OG1 2.74Å; D239-T280 VanDerWaalsContact O-OG1 3.04Å; L240-T280 PolarHBondContact O-N 3.2Å; L240-T280 PolarHBondContact O-OG1 2.95Å; T241-T280 PolarHBondContact N-OG1 3.06Å; T241-T280 VanDerWaalsContact N-OG1 3.14Å; T280-G282 VanDerWaalsContact C-N 3.32Å
281D94.2Very high89.7Confident33 Ų3338.5 Ų38.518%0.17620%0.199CC..THydrogen-bonded Turntrans-86.17.9171.558-15.3000113.8S206 T241 A242 G279 Q283S206-D281 WeakPolarHBondContact OG-CA 3.43Å; T241-D281 HydrophobicContact CG2-CB 4Å; A242-D281 VanDerWaalsContact N-CG 3.33Å; A242-D281 PolarHBondContact N-OD1 3.31Å; A242-D281 PolarHBondContact N-OD2 3.07Å; A242-D281 VanDerWaalsContact N-OD2 3.17Å; G279-D281 WeakPolarHBondContact CA-OD1 3.2Å; G279-D281 PolarHBondContact O-N 3.01Å; D281-Q283 HydrophobicContact CB-CG 4.39Å; D281-Q283 PolarHBondContact O-N 2.98Å; D281-Q283 VanDerWaalsContact O-N 3.09Å; D281-Q283 PolarHBondContact OD1-N 3.25Å
282G89Confident89.8Confident17 Ų1740.5 Ų40.518%0.17521%0.208CC..SBendtrans68.36-178.100000114.4Y278 G279 T280Y278-G282 WeakPolarHBondContact CD1-O 3.33Å; Y278-G282 WeakPolarHBondContact CE1-O 3.14Å; G279-G282 PolarHBondContact O-N 2.66Å; G279-G282 VanDerWaalsContact O-N 3.07Å; T280-G282 VanDerWaalsContact C-N 3.32Å
283Q93.7Very high90.1Very high111 Ų11140.8 Ų40.852%0.51921%0.21SC..  trans-86.8147.4177.9-61-51.8-5900111A242 Y278 G279 D281A242-Q283 HydrophobicContact CB-CB 3.61Å; Y278-Q283 WeakPolarHBondContact CA-O 3.13Å; G279-Q283 PolarHBondContact N-O 3.45Å; D281-Q283 HydrophobicContact CB-CG 4.39Å; D281-Q283 PolarHBondContact O-N 2.98Å; D281-Q283 VanDerWaalsContact O-N 3.09Å; D281-Q283 PolarHBondContact OD1-N 3.25Å
284L89.9Confident90.6Very high57 Ų5738.7 Ų38.730%0.29820%0.197SC..EExtended strand (participates in β ladder)trans-92.7148.5-177.4-74.2174.1000113.4R246 V273 A276 I277 Y278R246-L284 PolarHBondContact NH2-O 2.89Å; V273-L284 HydrophobicContact CG2-CD1 4.07Å; V273-L284 HydrophobicContact CG2-CD2 4.17Å; A276-L284 HydrophobicContact CB-CB 4.37Å; A276-L284 HydrophobicContact CB-CD1 4.34Å; A276-L284 HydrophobicContact CB-CD2 3.97Å; A276-L284 HydrophobicContact CB-CG 4.47Å; I277-L284 WeakPolarHBondContact O-CA 3.43Å; Y278-L284 HydrophobicContact CD1-CD2 3.48Å; Y278-L284 VanDerWaalsContact CD1-CD2 3.48Å; Y278-L284 HydrophobicContact CD1-CG 3.98Å; Y278-L284 HydrophobicContact CD2-CD2 3.94Å; Y278-L284 HydrophobicContact CE1-CD1 4.4Å; Y278-L284 HydrophobicContact CE1-CD2 3.48Å; Y278-L284 VanDerWaalsContact CE1-CD2 3.48Å; Y278-L284 HydrophobicContact CE1-CG 3.74Å; Y278-L284 HydrophobicContact CE2-CD2 3.93Å; Y278-L284 HydrophobicContact CG-CD2 3.73Å
285I93.4Very high90.9Very high1 Ų133.9 Ų33.91%0.00518%0.175CC..EExtended strand (participates in β ladder)trans-120.4126.1165-57.1177.9000108A242 M245 R246 A276 I277 W289 V290A242-I285 HydrophobicContact CB-CD1 4.2Å; A242-I285 HydrophobicContact CB-CG1 3.94Å; A242-I285 WeakPolarHBondContact O-CD1 3.44Å; M245-I285 HydrophobicContact CB-CD1 3.41Å; M245-I285 VanDerWaalsContact CB-CD1 3.41Å; M245-I285 HydrophobicContact CE-CD1 4.13Å; M245-I285 HydrophobicContact CG-CD1 4.23Å; M245-I285 HydrophobicContact SD-CD1 3.88Å; R246-I285 HydrophobicContact CG-CD1 4.16Å; R246-I285 HydrophobicContact CG-CG1 4.49Å; A276-I285 CarbonylContact C-O 3.46Å; A276-I285 VanDerWaalsContact CA-O 3.23Å; A276-I285 WeakPolarHBondContact CA-O 3.29Å; A276-I285 WeakPolarHBondContact CB-O 3.35Å; I277-I285 HydrophobicContact CG1-CB 4.22Å; I277-I285 PolarHBondContact N-O 3.01Å; I277-I285 PolarHBondContact O-N 3.42Å; I285-W289 HydrophobicContact CG2-CE3 3.68Å; I285-W289 HydrophobicContact CG2-CZ3 4.1Å; I285-V290 HydrophobicContact CG2-CG2 3.96Å
286Q92.4Very high90.7Very high102 Ų10233.1 Ų33.148%0.47716%0.164SC..EExtended strand (participates in β ladder)trans-72.8130.2173.9-59.6-58.8-34.300109.8D288 W289 V290Q286-D288 PolarHBondContact O-N 3.34Å; Q286-W289 WeakPolarHBondContact O-CB 3.48Å; Q286-W289 PolarHBondContact O-N 3.35Å; Q286-W289 VanDerWaalsContact O-N 3.16Å; Q286-V290 PolarHBondContact O-N 3.49Å
287L89.5Confident90.2Very high9 Ų936.2 Ų36.25%0.04719%0.189CC..Hα-helixtrans-64.8-29.5177.5-68.3169.5000111.4L268 G275 I277 W289 V290 F291 I311 F375L268-L287 HydrophobicContact CD1-CD2 4.36Å; G275-L287 WeakPolarHBondContact O-CB 3.35Å; G275-L287 WeakPolarHBondContact O-CG 3.3Å; G275-L287 PolarHBondContact O-N 2.95Å; I277-L287 HydrophobicContact CD1-CD2 4.16Å; I277-L287 HydrophobicContact CG1-CD2 4.39Å; I277-L287 HydrophobicContact CG2-CD1 4.43Å; I277-L287 HydrophobicContact CG2-CD2 4Å; I277-L287 HydrophobicContact CG2-CG 4.37Å; L287-W289 VanDerWaalsContact C-N 3.31Å; L287-W289 PolarHBondContact O-N 3.48Å; L287-V290 WeakPolarHBondContact O-CA 3.25Å; L287-V290 WeakPolarHBondContact O-CB 3.25Å; L287-V290 PolarHBondContact O-N 2.73Å; L287-V290 VanDerWaalsContact O-N 3.07Å; L287-F291 HydrophobicContact CB-CD2 4.46Å; L287-F291 HydrophobicContact CB-CE2 3.85Å; L287-F291 HydrophobicContact CB-CZ 4.19Å; L287-F291 WeakPolarHBondContact O-CD2 3.46Å; L287-F291 VanDerWaalsContact O-CG 3.31Å; L287-F291 WeakPolarHBondContact O-CG 3.46Å; L287-F291 PolarHBondContact O-N 2.87Å; L287-I311 HydrophobicContact CD1-CG2 4.15Å; L287-I311 HydrophobicContact CD2-CD1 4.13Å; L287-I311 HydrophobicContact CD2-CG2 4.29Å; L287-F375 HydrophobicContact CD1-CE1 4.26Å
288D88.7Confident89.8Confident89 Ų8941.3 Ų41.348%0.47621%0.213SC..Hα-helixtrans-58.6-38.9172.1-98.6-61.8000113.5Q286 V290 F291 E292 R368Q286-D288 PolarHBondContact O-N 3.34Å; D288-V290 VanDerWaalsContact C-N 3.34Å; D288-F291 PolarHBondContact O-N 2.99Å; D288-E292 VanDerWaalsContact O-CB 3.26Å; D288-E292 WeakPolarHBondContact O-CB 3.34Å; D288-E292 PolarHBondContact O-N 3.02Å; D288-R368 PolarHBondContact O-NH2 2.95Å; D288-R368 VanDerWaalsContact O-NH2 3.07Å; D288-R368 IonicContact OD1-CZ 3.57Å; D288-R368 VanDerWaalsContact OD1-CZ 3.24Å; D288-R368 IonicContact OD1-NH1 2.65Å; D288-R368 PolarHBondContact OD1-NH1 2.9Å; D288-R368 IonicContact OD1-NH2 3.31Å; D288-R368 PolarHBondContact OD1-NH2 3.25Å
289W93.4Very high89.5Confident72 Ų7238.8 Ų38.827%0.27320%0.203SC..Hα-helixtrans-67.3-36.6173.9171.784.3000111.4R246 I249 E250 I285 Q286 L287 A293R246-W289 HydrophobicContact CB-CH2 3.82Å; R246-W289 HydrophobicContact CB-CZ2 4.32Å; R246-W289 HydrophobicContact CB-CZ3 4.39Å; R246-W289 HydrophobicContact CG-CH2 3.73Å; R246-W289 HydrophobicContact CG-CZ2 4.15Å; R246-W289 HydrophobicContact CG-CZ3 3.91Å; I249-W289 HydrophobicContact CB-CH2 4.28Å; I249-W289 HydrophobicContact CB-CZ3 4.34Å; I249-W289 HydrophobicContact CD1-CZ3 4.15Å; I249-W289 HydrophobicContact CG2-CH2 4.13Å; I249-W289 HydrophobicContact CG2-CZ3 4.12Å; E250-W289 HydrophobicContact CG-CH2 4.31Å; E250-W289 HydrophobicContact CG-CZ2 4.1Å; I285-W289 HydrophobicContact CG2-CE3 3.68Å; I285-W289 HydrophobicContact CG2-CZ3 4.1Å; Q286-W289 WeakPolarHBondContact O-CB 3.48Å; Q286-W289 PolarHBondContact O-N 3.35Å; Q286-W289 VanDerWaalsContact O-N 3.16Å; L287-W289 VanDerWaalsContact C-N 3.31Å; L287-W289 PolarHBondContact O-N 3.48Å; W289-A293 WeakPolarHBondContact O-CB 3.35Å; W289-A293 PolarHBondContact O-N 2.96Å
290V94.2Very high89Confident0 Ų042.3 Ų42.30%023%0.226CC..Hα-helixtrans-63.2-50.7173.8-177.20000109.9I249 L268 I285 Q286 L287 D288 E292 A293 F294 F309I249-V290 HydrophobicContact CD1-CG1 4.31Å; I249-V290 HydrophobicContact CD1-CG2 4.09Å; L268-V290 HydrophobicContact CD1-CG1 4.13Å; L268-V290 HydrophobicContact CD1-CG2 4.39Å; I285-V290 HydrophobicContact CG2-CG2 3.96Å; Q286-V290 PolarHBondContact O-N 3.49Å; L287-V290 WeakPolarHBondContact O-CA 3.25Å; L287-V290 WeakPolarHBondContact O-CB 3.25Å; L287-V290 PolarHBondContact O-N 2.73Å; L287-V290 VanDerWaalsContact O-N 3.07Å; D288-V290 VanDerWaalsContact C-N 3.34Å; V290-E292 VanDerWaalsContact C-N 3.32Å; V290-E292 PolarHBondContact O-N 3.13Å; V290-A293 PolarHBondContact O-N 3.02Å; V290-F294 HydrophobicContact CG1-CD2 4.34Å; V290-F294 HydrophobicContact CG1-CE2 4.21Å; V290-F294 VanDerWaalsContact O-CD2 3.29Å; V290-F294 WeakPolarHBondContact O-CD2 3.47Å; V290-F294 PolarHBondContact O-N 2.95Å; V290-F309 HydrophobicContact CG1-CE1 4.29Å
291F92.2Very high88.7Confident25 Ų2544.6 Ų44.611%0.1124%0.238CC..Hα-helixtrans-64.1-36.1-179.9-56.7-43.5000112.3L287 D288 F294 D295 F309 M371 C373 F375L287-F291 HydrophobicContact CB-CD2 4.46Å; L287-F291 HydrophobicContact CB-CE2 3.85Å; L287-F291 HydrophobicContact CB-CZ 4.19Å; L287-F291 WeakPolarHBondContact O-CD2 3.46Å; L287-F291 VanDerWaalsContact O-CG 3.31Å; L287-F291 WeakPolarHBondContact O-CG 3.46Å; L287-F291 PolarHBondContact O-N 2.87Å; D288-F291 PolarHBondContact O-N 2.99Å; F291-F294 PolarHBondContact O-N 2.96Å; F291-D295 PolarHBondContact O-N 2.91Å; F291-F309 HydrophobicContact CD1-CD1 4.05Å; F291-F309 HydrophobicContact CD1-CD2 4.23Å; F291-F309 HydrophobicContact CD1-CE1 4.05Å; F291-F309 HydrophobicContact CD1-CE2 4.23Å; F291-F309 HydrophobicContact CD1-CG 4.15Å; F291-F309 HydrophobicContact CD1-CZ 4.14Å; F291-F309 HydrophobicContact CE1-CB 4.12Å; F291-F309 AromaticContact CE1-CD1 3.87Å; F291-F309 HydrophobicContact CE1-CD1 3.87Å; F291-F309 HydrophobicContact CE1-CD2 4.18Å; F291-F309 HydrophobicContact CE1-CE1 4.35Å; F291-F309 AromaticContact CE1-CG 3.79Å; F291-F309 HydrophobicContact CE1-CG 3.79Å; F291-M371 VanDerWaalsContact O-CE 3.29Å; F291-M371 WeakPolarHBondContact O-CE 3.43Å; F291-C373 HydrophobicContact CE1-CB 4.41Å; F291-C373 WeakPolarHBondContact CE1-SG 3.24Å; F291-C373 HydrophobicContact CZ-CB 4.36Å; F291-F375 HydrophobicContact CE2-CZ 4.43Å; F291-F375 HydrophobicContact CZ-CE1 4.26Å; F291-F375 HydrophobicContact CZ-CZ 4.01Å
292E89.5Confident88.5Confident81 Ų8143 Ų4338%0.37923%0.229SC..Hα-helixtrans-61.6-42.7172.4-178.7169.3-142.300112.4D288 V290 F294 D295 H298D288-E292 VanDerWaalsContact O-CB 3.26Å; D288-E292 WeakPolarHBondContact O-CB 3.34Å; D288-E292 PolarHBondContact O-N 3.02Å; V290-E292 VanDerWaalsContact C-N 3.32Å; V290-E292 PolarHBondContact O-N 3.13Å; E292-F294 PolarHBondContact O-N 2.84Å; E292-F294 VanDerWaalsContact O-N 3.09Å; E292-D295 VanDerWaalsContact O-CB 3.3Å; E292-D295 WeakPolarHBondContact O-CB 3.44Å; E292-D295 PolarHBondContact O-N 3.42Å; E292-H298 WeakPolarHBondContact O-CB 3.47Å; E292-H298 PolarHBondContact O-ND1 3.2Å; E292-H298 VanDerWaalsContact O-ND1 3.15Å; E292-H298 IonicContact OE1-CE1 3.8Å
293A92.1Very high88.3Confident15 Ų1546 Ų4612%0.12424%0.239CC..Hα-helixtrans-63-16.7177.800000114.4I249 C253 W289 V290I249-A293 HydrophobicContact CG2-CB 4.41Å; C253-A293 PolarHBondContact SG-O 2.77Å; W289-A293 WeakPolarHBondContact O-CB 3.35Å; W289-A293 PolarHBondContact O-N 2.96Å; V290-A293 PolarHBondContact O-N 3.02Å
294F92.1Very high87.9Confident0 Ų045.3 Ų45.30%024%0.238CC..THydrogen-bonded Turntrans-107.27174.7-73.2-79.8000113.6I249 F252 C253 V266 V290 F291 E292 L302 K307 F309 M371I249-F294 HydrophobicContact CG2-CE2 3.91Å; I249-F294 HydrophobicContact CG2-CZ 4.42Å; F252-F294 AromaticContact CD1-CE1 3.66Å; F252-F294 HydrophobicContact CD1-CE1 3.66Å; F252-F294 AromaticContact CD1-CZ 3.67Å; F252-F294 HydrophobicContact CD1-CZ 3.67Å; F252-F294 AromaticContact CE1-CE1 3.83Å; F252-F294 HydrophobicContact CE1-CE1 3.83Å; F252-F294 HydrophobicContact CE1-CZ 4.07Å; C253-F294 WeakPolarHBondContact SG-CE1 3.28Å; C253-F294 WeakPolarHBondContact SG-CZ 3.47Å; V266-F294 HydrophobicContact CG1-CE2 4.39Å; V266-F294 HydrophobicContact CG2-CE1 3.86Å; V266-F294 HydrophobicContact CG2-CE2 3.74Å; V266-F294 HydrophobicContact CG2-CZ 3.36Å; V290-F294 HydrophobicContact CG1-CD2 4.34Å; V290-F294 HydrophobicContact CG1-CE2 4.21Å; V290-F294 VanDerWaalsContact O-CD2 3.29Å; V290-F294 WeakPolarHBondContact O-CD2 3.47Å; V290-F294 PolarHBondContact O-N 2.95Å; F291-F294 PolarHBondContact O-N 2.96Å; E292-F294 PolarHBondContact O-N 2.84Å; E292-F294 VanDerWaalsContact O-N 3.09Å; F294-L302 HydrophobicContact CD1-CD1 4.21Å; F294-K307 HydrophobicContact CB-CD 4.27Å; F294-K307 WeakPolarHBondContact O-CD 3.16Å; F294-K307 WeakPolarHBondContact O-CE 3.42Å; F294-F309 HydrophobicContact CB-CZ 3.77Å; F294-F309 AromaticContact CD2-CE1 3.56Å; F294-F309 HydrophobicContact CD2-CE1 3.56Å; F294-F309 AromaticContact CD2-CZ 3.67Å; F294-F309 HydrophobicContact CD2-CZ 3.67Å; F294-F309 AromaticContact CE2-CE1 3.95Å; F294-F309 HydrophobicContact CE2-CE1 3.95Å; F294-F309 HydrophobicContact CE2-CZ 4.43Å; F294-F309 HydrophobicContact CG-CE1 4.12Å; F294-F309 AromaticContact CG-CZ 3.77Å; F294-F309 HydrophobicContact CG-CZ 3.77Å; F294-M371 HydrophobicContact CB-CE 4.16Å; F294-M371 VanDerWaalsContact O-CE 3.29Å; F294-M371 WeakPolarHBondContact O-CE 3.19Å
295D84.4Confident88.1Confident2 Ų244.2 Ų44.21%0.01123%0.231CC..SBendtrans-72.8170.7-178.197.6-11.6000112.6F291 E292 A297 H298 C299 Q367 R368 M371F291-D295 PolarHBondContact O-N 2.91Å; E292-D295 VanDerWaalsContact O-CB 3.3Å; E292-D295 WeakPolarHBondContact O-CB 3.44Å; E292-D295 PolarHBondContact O-N 3.42Å; D295-A297 PolarHBondContact O-N 3.24Å; D295-A297 VanDerWaalsContact O-N 3.17Å; D295-A297 WeakPolarHBondContact OD1-CA 3.31Å; D295-A297 WeakPolarHBondContact OD1-CB 3.42Å; D295-A297 PolarHBondContact OD1-N 3.09Å; D295-H298 PolarHBondContact O-N 3.19Å; D295-H298 IonicContact OD1-CE1 3.67Å; D295-H298 IonicContact OD1-CG 2.69Å; D295-H298 PolarHBondContact OD1-N 3.2Å; D295-H298 IonicContact OD1-ND1 3.82Å; D295-H298 PolarHBondContact OD1-ND1 3.42Å; D295-H298 IonicContact OD2-ND1 3.95Å; D295-C299 PolarHBondContact O-N 2.82Å; D295-Q367 WeakPolarHBondContact CB-O 3Å; D295-R368 HydrophobicContact CB-CG 4.12Å; D295-M371 HydrophobicContact CB-CE 4.11Å
296N77.3Confident88.2Confident10 Ų1044.2 Ų44.25%0.05323%0.231CC..THydrogen-bonded Turntrans-66.3-15.8-175.7-71.4-43.3000113.7Q303 P366 Q367 S369N296-Q303 HydrophobicContact CB-CG 4.08Å; N296-Q303 PolarHBondContact O-NE2 2.75Å; N296-Q303 WeakPolarHBondContact OD1-CA 3.38Å; N296-P366 PolarHBondContact ND2-O 2.9Å; N296-Q367 WeakPolarHBondContact CB-O 3.48Å; N296-Q367 PolarHBondContact N-O 2.63Å; N296-Q367 PolarHBondContact ND2-O 3.32Å; N296-S369 PolarHBondContact ND2-OG 3.16Å
297A75.2Confident88.4Confident67 Ų6739.4 Ų39.455%0.55421%0.209SC*.THydrogen-bonded Turntrans-90.8-43.6175.600000111.7D295D295-A297 PolarHBondContact O-N 3.24Å; D295-A297 VanDerWaalsContact O-N 3.17Å; D295-A297 WeakPolarHBondContact OD1-CA 3.31Å; D295-A297 WeakPolarHBondContact OD1-CB 3.42Å; D295-A297 PolarHBondContact OD1-N 3.09Å
298H84.1Confident88.8Confident108 Ų10839.1 Ų39.150%0.521%0.207SC..THydrogen-bonded Turntrans-85.7-30.2-174.3-61.4100.2000113.7E292 D295 P300E292-H298 WeakPolarHBondContact O-CB 3.47Å; E292-H298 PolarHBondContact O-ND1 3.2Å; E292-H298 VanDerWaalsContact O-ND1 3.15Å; E292-H298 IonicContact OE1-CE1 3.8Å; D295-H298 PolarHBondContact O-N 3.19Å; D295-H298 IonicContact OD1-CE1 3.67Å; D295-H298 IonicContact OD1-CG 2.69Å; D295-H298 PolarHBondContact OD1-N 3.2Å; D295-H298 IonicContact OD1-ND1 3.82Å; D295-H298 PolarHBondContact OD1-ND1 3.42Å; D295-H298 IonicContact OD2-ND1 3.95Å; H298-P300 VanDerWaalsContact C-CD 3.44Å; H298-P300 WeakPolarHBondContact O-CD 3.32Å
299C86Confident89.2Confident1 Ų134.9 Ų34.91%0.00719%0.185CC..  trans-120.470.6174.6-163.10000112C253 D295 L301 L302C253-C299 PolarHBondContact O-SG 2.97Å; D295-C299 PolarHBondContact O-N 2.82Å; C299-L301 PolarHBondContact O-N 3.13Å; C299-L302 PolarHBondContact O-N 2.89Å; C299-L302 VanDerWaalsContact SG-CD1 3.59Å
300P83.4Confident89.4Confident75 Ų7531.5 Ų31.549%0.48717%0.172SC..G310 helixtrans-62.2-18.5-17524.7-35000114.4H298 L302H298-P300 VanDerWaalsContact C-CD 3.44Å; H298-P300 WeakPolarHBondContact O-CD 3.32Å; P300-L302 VanDerWaalsContact C-N 3.28Å; P300-L302 PolarHBondContact O-N 3.14Å
301L88.8Confident89.3Confident61 Ų6131.6 Ų31.632%0.31917%0.172SC..G310 helixtrans-75.9-14.4176.7-57.8-178.9000113.5R255 H258 R259 C299 K305R255-L301 WeakPolarHBondContact O-CD1 3.4Å; H258-L301 HydrophobicContact CB-CB 3.69Å; H258-L301 HydrophobicContact CB-CD1 4.25Å; R259-L301 HydrophobicContact CB-CD2 4.32Å; C299-L301 PolarHBondContact O-N 3.13Å; L301-K305 PolarHBondContact O-NZ 2.86Å
302L88.8Confident89.3Confident1 Ų130.6 Ų30.61%0.00517%0.168CC..G310 helixtrans-11218178.4-61.7179.4000113.6H258 C264 F294 C299 P300 K305 K307H258-L302 HydrophobicContact CB-CD2 3.83Å; H258-L302 HydrophobicContact CB-CG 4.1Å; C264-L302 HydrophobicContact CB-CD1 4Å; C264-L302 VanDerWaalsContact SG-CD1 3.58Å; F294-L302 HydrophobicContact CD1-CD1 4.21Å; C299-L302 PolarHBondContact O-N 2.89Å; C299-L302 VanDerWaalsContact SG-CD1 3.59Å; P300-L302 VanDerWaalsContact C-N 3.28Å; P300-L302 PolarHBondContact O-N 3.14Å; L302-K305 HydrophobicContact CD2-CB 4.45Å; L302-K305 HydrophobicContact CD2-CD 4.05Å; L302-K305 PolarHBondContact O-N 3Å; L302-K307 HydrophobicContact CB-CD 4.15Å; L302-K307 HydrophobicContact CB-CG 4.36Å; L302-K307 HydrophobicContact CD1-CG 4.46Å; L302-K307 PolarHBondContact O-NZ 2.79Å
303Q86.4Confident89Confident80 Ų8026.9 Ų26.937%0.37415%0.151SC..THydrogen-bonded Turntrans-64.2134170.7-71.9176.72.400111.4N296 K305 L365N296-Q303 HydrophobicContact CB-CG 4.08Å; N296-Q303 PolarHBondContact O-NE2 2.75Å; N296-Q303 WeakPolarHBondContact OD1-CA 3.38Å; Q303-K305 PolarHBondContact O-N 3.4Å; Q303-L365 HydrophobicContact CB-CD1 4.33Å
304N84.6Confident88.3Confident95 Ų9527.6 Ų27.651%0.50816%0.155SC..THydrogen-bonded Turntrans60.315.1-176.3-38.4-97.8000114.3D370N304-D370 WeakPolarHBondContact CA-OD2 3.43Å; N304-D370 PolarHBondContact N-OD2 2.72Å
305K93.4Very high87.2Confident35 Ų3528.4 Ų28.415%0.15216%0.158CC..SBendtrans-109.5138.1177.3-68-172.7-171.8179.60110H258 R259 V261 D262 L301 L302 Q303 K307 D370H258-K305 PolarHBondContact O-NZ 3.22Å; R259-K305 PolarHBondContact O-NZ 3.37Å; V261-K305 WeakPolarHBondContact O-CE 3.41Å; V261-K305 PolarHBondContact O-NZ 3.2Å; D262-K305 VanDerWaalsContact O-CB 3.27Å; D262-K305 WeakPolarHBondContact O-CB 3.37Å; D262-K305 WeakPolarHBondContact O-CG 3.27Å; L301-K305 PolarHBondContact O-NZ 2.86Å; L302-K305 HydrophobicContact CD2-CB 4.45Å; L302-K305 HydrophobicContact CD2-CD 4.05Å; L302-K305 PolarHBondContact O-N 3Å; Q303-K305 PolarHBondContact O-N 3.4Å; K305-K307 PolarHBondContact O-N 2.99Å; K305-K307 PolarHBondContact O-NZ 2.96Å; K305-D370 VanDerWaalsContact O-CB 3.31Å; K305-D370 WeakPolarHBondContact O-CB 3.44Å
306P95.8Very high86.1Confident1 Ų129 Ų291%0.00617%0.165CC..  trans-64.9127.9179.125.6-34.1000111.6Y184 M186 D262 C264 D370 L446 L450Y184-P306 HydrophobicContact CD1-CG 4.36Å; Y184-P306 HydrophobicContact CD2-CB 4.21Å; Y184-P306 HydrophobicContact CD2-CG 4.35Å; Y184-P306 HydrophobicContact CE2-CB 4.33Å; Y184-P306 HydrophobicContact CG-CB 4.34Å; Y184-P306 HydrophobicContact CG-CG 4.06Å; M186-P306 HydrophobicContact SD-CG 3.82Å; D262-P306 WeakPolarHBondContact O-CD 3.44Å; C264-P306 PolarHBondContact N-O 2.83Å; P306-D370 CarbonylContact C-O 3.57Å; P306-D370 WeakPolarHBondContact CA-O 3.38Å; P306-L446 HydrophobicContact CB-CD2 4.47Å; P306-L450 HydrophobicContact CB-CD1 3.68Å; P306-L450 HydrophobicContact CB-CD2 3.63Å; P306-L450 HydrophobicContact CB-CG 4.27Å; P306-L450 HydrophobicContact CG-CD1 3.64Å; P306-L450 HydrophobicContact CG-CD2 4.49Å
307K96.3Very high85.1Confident1 Ų135.8 Ų35.80%0.00420%0.201CC..EExtended strand (participates in β ladder)trans-116.8105.2-178.4-68.6169.7-73.5-68.70108.3F294 L302 K305 F309 S369 D370 M371 I372F294-K307 HydrophobicContact CB-CD 4.27Å; F294-K307 WeakPolarHBondContact O-CD 3.16Å; F294-K307 WeakPolarHBondContact O-CE 3.42Å; L302-K307 HydrophobicContact CB-CD 4.15Å; L302-K307 HydrophobicContact CB-CG 4.36Å; L302-K307 HydrophobicContact CD1-CG 4.46Å; L302-K307 PolarHBondContact O-NZ 2.79Å; K305-K307 PolarHBondContact O-N 2.99Å; K305-K307 PolarHBondContact O-NZ 2.96Å; K307-F309 HydrophobicContact CB-CE2 3.93Å; K307-F309 HydrophobicContact CB-CZ 4.48Å; K307-S369 WeakPolarHBondContact CE-O 3.42Å; K307-S369 PolarHBondContact NZ-O 3.06Å; K307-S369 VanDerWaalsContact NZ-O 3.14Å; K307-D370 PolarHBondContact N-O 2.96Å; K307-D370 IonicContact NZ-OD2 2.98Å; K307-M371 HydrophobicContact CB-CG 4.09Å; K307-M371 HydrophobicContact CD-CE 4.28Å; K307-M371 HydrophobicContact CD-CG 4.36Å; K307-M371 VanDerWaalsContact O-CA 3.32Å; K307-M371 WeakPolarHBondContact O-CA 3.19Å; K307-I372 PolarHBondContact O-N 3.41Å
308M97.8Very high84Confident2 Ų239.2 Ų39.21%0.0121%0.206CC..EExtended strand (participates in β ladder)trans-100.7126.1-173.1-67.8164.2-81.100111Y232 C264 V265 V266 F310 I372 L410 L450 L452Y232-M308 HydrophobicContact CE1-CE 4.18Å; Y232-M308 WeakPolarHBondContact OH-CE 3.37Å; C264-M308 PolarHBondContact O-N 2.88Å; V265-M308 CarbonylContact C-O 3.52Å; V265-M308 WeakPolarHBondContact CA-O 3.29Å; V265-M308 HydrophobicContact CG2-CB 4.19Å; V265-M308 HydrophobicContact CG2-CE 3.64Å; V265-M308 HydrophobicContact CG2-SD 4.21Å; V266-M308 PolarHBondContact N-O 2.87Å; M308-F310 HydrophobicContact CB-CE2 3.99Å; M308-F310 HydrophobicContact CB-CZ 4.18Å; M308-I372 HydrophobicContact CB-CG2 4.37Å; M308-I372 HydrophobicContact CG-CG2 3.78Å; M308-L410 HydrophobicContact CG-CD2 3.64Å; M308-L410 HydrophobicContact SD-CD2 3.65Å; M308-L450 HydrophobicContact CG-CD2 3.92Å; M308-L450 HydrophobicContact SD-CD2 3.92Å; M308-L452 HydrophobicContact CE-CD2 4.49Å; M308-L452 HydrophobicContact SD-CD2 4.1Å
309F97.5Very high82.3Confident0 Ų038.1 Ų38.10%020%0.202CC..EExtended strand (participates in β ladder)trans-117.4134177.8-59.2-94000110.9V266 V290 F291 F294 K307 I311 M371 I372 C373 G374V266-F309 HydrophobicContact CB-CD1 3.71Å; V266-F309 HydrophobicContact CB-CE1 3.9Å; V266-F309 HydrophobicContact CG1-CD1 4.13Å; V266-F309 HydrophobicContact CG1-CE1 4.29Å; V266-F309 HydrophobicContact CG2-CD1 4.28Å; V266-F309 HydrophobicContact CG2-CE1 3.97Å; V266-F309 VanDerWaalsContact O-CA 3.3Å; V266-F309 WeakPolarHBondContact O-CA 3.37Å; V290-F309 HydrophobicContact CG1-CE1 4.29Å; F291-F309 HydrophobicContact CD1-CD1 4.05Å; F291-F309 HydrophobicContact CD1-CD2 4.23Å; F291-F309 HydrophobicContact CD1-CE1 4.05Å; F291-F309 HydrophobicContact CD1-CE2 4.23Å; F291-F309 HydrophobicContact CD1-CG 4.15Å; F291-F309 HydrophobicContact CD1-CZ 4.14Å; F291-F309 HydrophobicContact CE1-CB 4.12Å; F291-F309 AromaticContact CE1-CD1 3.87Å; F291-F309 HydrophobicContact CE1-CD1 3.87Å; F291-F309 HydrophobicContact CE1-CD2 4.18Å; F291-F309 HydrophobicContact CE1-CE1 4.35Å; F291-F309 AromaticContact CE1-CG 3.79Å; F291-F309 HydrophobicContact CE1-CG 3.79Å; F294-F309 HydrophobicContact CB-CZ 3.77Å; F294-F309 AromaticContact CD2-CE1 3.56Å; F294-F309 HydrophobicContact CD2-CE1 3.56Å; F294-F309 AromaticContact CD2-CZ 3.67Å; F294-F309 HydrophobicContact CD2-CZ 3.67Å; F294-F309 AromaticContact CE2-CE1 3.95Å; F294-F309 HydrophobicContact CE2-CE1 3.95Å; F294-F309 HydrophobicContact CE2-CZ 4.43Å; F294-F309 HydrophobicContact CG-CE1 4.12Å; F294-F309 AromaticContact CG-CZ 3.77Å; F294-F309 HydrophobicContact CG-CZ 3.77Å; K307-F309 HydrophobicContact CB-CE2 3.93Å; K307-F309 HydrophobicContact CB-CZ 4.48Å; F309-I311 HydrophobicContact CB-CD1 4.4Å; F309-M371 HydrophobicContact CE2-CB 4.25Å; F309-M371 HydrophobicContact CE2-CG 4.1Å; F309-M371 HydrophobicContact CE2-SD 4.41Å; F309-I372 PolarHBondContact N-O 3.4Å; F309-C373 HydrophobicContact CB-CB 4.15Å; F309-C373 VanDerWaalsContact CD2-SG 3.51Å; F309-C373 WeakPolarHBondContact O-CA 3.35Å; F309-G374 PolarHBondContact O-N 3.5Å
310F97.3Very high80.4Confident2 Ų240.8 Ų40.81%0.00922%0.216CC..EExtended strand (participates in β ladder)trans-128.5106.5177.2-57.9-67.3000109.5F227 V265 V266 S267 L268 M308 F393 L397 L410 L414F227-F310 HydrophobicContact CE1-CE2 4.23Å; F227-F310 HydrophobicContact CE2-CD2 4.47Å; F227-F310 AromaticContact CZ-CD2 3.9Å; F227-F310 HydrophobicContact CZ-CD2 3.9Å; F227-F310 AromaticContact CZ-CE2 3.62Å; F227-F310 HydrophobicContact CZ-CE2 3.62Å; V265-F310 HydrophobicContact CG1-CD2 3.82Å; V265-F310 HydrophobicContact CG1-CE2 3.83Å; V266-F310 PolarHBondContact O-N 3.05Å; S267-F310 CarbonylContact C-O 3.25Å; S267-F310 VanDerWaalsContact CA-O 3.3Å; S267-F310 WeakPolarHBondContact CA-O 3.47Å; L268-F310 PolarHBondContact N-O 3.35Å; M308-F310 HydrophobicContact CB-CE2 3.99Å; M308-F310 HydrophobicContact CB-CZ 4.18Å; F310-F393 HydrophobicContact CB-CE1 4.42Å; F310-F393 HydrophobicContact CD1-CZ 4.34Å; F310-L397 HydrophobicContact CB-CD2 4.2Å; F310-L397 HydrophobicContact CD1-CD1 4.23Å; F310-L397 HydrophobicContact CD1-CD2 3.47Å; F310-L397 VanDerWaalsContact CD1-CD2 3.47Å; F310-L397 HydrophobicContact CD2-CD2 4.26Å; F310-L397 HydrophobicContact CE1-CD1 3.79Å; F310-L397 HydrophobicContact CE1-CD2 3.84Å; F310-L397 HydrophobicContact CE1-CG 4.48Å; F310-L397 HydrophobicContact CG-CD2 3.71Å; F310-L397 HydrophobicContact CZ-CD1 4.31Å; F310-L397 HydrophobicContact CZ-CD2 4.37Å; F310-L410 HydrophobicContact CZ-CD1 4.46Å; F310-L410 HydrophobicContact CZ-CD2 4.24Å; F310-L414 HydrophobicContact CE1-CD2 4.38Å
311I93.1Very high78.6Confident2 Ų242.5 Ų42.51%0.0123%0.229CC..EExtended strand (participates in β ladder)trans-108.4102.3-168.8-49.8-58.3000109.8L268 I277 L287 F309 A313 G374 F375 A376L268-I311 HydrophobicContact CB-CD1 3.97Å; L268-I311 HydrophobicContact CD1-CD1 3.92Å; L268-I311 HydrophobicContact CG-CD1 4.08Å; I277-I311 HydrophobicContact CG2-CG2 4.42Å; L287-I311 HydrophobicContact CD1-CG2 4.15Å; L287-I311 HydrophobicContact CD2-CD1 4.13Å; L287-I311 HydrophobicContact CD2-CG2 4.29Å; F309-I311 HydrophobicContact CB-CD1 4.4Å; I311-A313 HydrophobicContact CG2-CB 4.38Å; I311-A313 PolarHBondContact O-N 3.24Å; I311-G374 PolarHBondContact N-O 2.91Å; I311-F375 HydrophobicContact CB-CD1 3.77Å; I311-F375 HydrophobicContact CB-CE1 4.22Å; I311-F375 HydrophobicContact CG1-CD1 3.98Å; I311-F375 HydrophobicContact CG1-CE1 3.92Å; I311-F375 HydrophobicContact CG2-CD1 4.14Å; I311-A376 PolarHBondContact O-N 2.71Å
312Q91Very high76.2Confident3 Ų341.1 Ų41.11%0.01423%0.229CC..EExtended strand (participates in β ladder)trans-97.982.2173.5-176.762.563.200109.7R213 L268 L269 S270 A376 S391 I394R213-Q312 PolarHBondContact NH2-O 2.9Å; L268-Q312 PolarHBondContact O-N 3.42Å; L269-Q312 WeakPolarHBondContact CA-O 3.48Å; L269-Q312 HydrophobicContact CB-CB 4.25Å; L269-Q312 HydrophobicContact CD2-CB 3.54Å; L269-Q312 HydrophobicContact CD2-CG 4.49Å; L269-Q312 HydrophobicContact CG-CB 4.49Å; S270-Q312 PolarHBondContact N-O 2.78Å; Q312-A376 VanDerWaalsContact CD-CB 3.47Å; Q312-A376 VanDerWaalsContact OE1-CB 3.26Å; Q312-S391 PolarHBondContact NE2-OG 2.93Å; Q312-S391 PolarHBondContact OE1-OG 2.85Å; Q312-I394 HydrophobicContact CB-CD1 4.25Å; Q312-I394 HydrophobicContact CB-CG1 4.31Å; Q312-I394 HydrophobicContact CG-CG1 4.27Å
313A84.2Confident74.3Confident3 Ų347.9 Ų47.93%0.02527%0.27CS..SBendtrans-145.9155.9173.400000110.1I277 I311 S377 A383I277-A313 HydrophobicContact CG2-CB 3.77Å; I311-A313 HydrophobicContact CG2-CB 4.38Å; I311-A313 PolarHBondContact O-N 3.24Å; A313-S377 PolarHBondContact O-OG 2.89Å; A313-A383 WeakPolarHBondContact O-CB 3.23Å
314C76.1Confident72Confident31 Ų3151.5 Ų51.521%0.20929%0.287CS..  trans-66.1153.9165.9-56.10000109.9G272 V273 A383G272-C314 CarbonylContact C-O 3.49Å; G272-C314 WeakPolarHBondContact CA-O 3.42Å; V273-C314 PolarHBondContact N-O 3.01Å; C314-A383 PolarHBondContact SG-N 3.27Å; C314-A383 VanDerWaalsContact SG-N 3.37Å
315R69.6Low69.7Low17 Ų1754.2 Ų54.26%0.06430%0.296CS..SBendtrans-126.119.7178.9-66.1169.773.3-172.64.8112.3E274 F375 S377 L378 G380 T381 E441E274-R315 WeakPolarHBondContact CA-O 3.09Å; E274-R315 VanDerWaalsContact CB-O 3.31Å; E274-R315 WeakPolarHBondContact CB-O 3.39Å; E274-R315 PolarHBondContact N-O 2.85Å; R315-F375 VanDerWaalsContact NH1-CB 3.27Å; R315-S377 WeakPolarHBondContact CD-O 3.41Å; R315-S377 WeakPolarHBondContact CD-OG 3.36Å; R315-S377 WeakPolarHBondContact CG-OG 3.17Å; R315-S377 PolarHBondContact NH1-O 3.3Å; R315-L378 WeakPolarHBondContact CB-O 3.19Å; R315-G380 WeakPolarHBondContact O-CA 3.22Å; R315-G380 PolarHBondContact O-N 3.43Å; R315-T381 PolarHBondContact N-O 2.7Å; R315-E441 IonicContact CZ-OE1 3.41Å; R315-E441 VanDerWaalsContact CZ-OE1 3.23Å; R315-E441 IonicContact NH1-OE1 3.19Å; R315-E441 PolarHBondContact NH1-OE1 2.88Å; R315-E441 IonicContact NH1-OE2 2.66Å; R315-E441 IonicContact NH2-OE1 2.69Å; R315-E441 PolarHBondContact NH2-OE1 2.78Å
316G61.8Low66.8Low15 Ų1559.7 Ų59.716%0.15533%0.327CS..SBendtrans156.6-177.7176.800000109.2G380 T381 A382G316-G380 CarbonylContact C-O 3.58Å; G316-G380 VanDerWaalsContact C-O 3.25Å; G316-G380 WeakPolarHBondContact CA-O 3.43Å; G316-T381 CarbonylContact O-C 3.56Å; G316-A382 PolarHBondContact O-N 3.1Å
317D56.2Low64.1Low151 Ų15166.8 Ų66.881%0.80737%0.365SS*.SBendtrans-99.2-2.5-173.1-56.7-38.2000112.9G380D317-G380 PolarHBondContact N-O 2.93Å
318E51Low61.2Low139 Ų13969 Ų6965%0.6539%0.388SS*.BIsolated β-bridgetrans-75.7130.7-175.9-59.4-175.1167.400110.8G380 T381 A382E318-G380 WeakPolarHBondContact CB-O 3.25Å; E318-G380 PolarHBondContact N-O 2.73Å; E318-T381 CarbonylContact O-C 3.5Å; E318-T381 WeakPolarHBondContact O-CA 3.42Å; E318-T381 WeakPolarHBondContact O-CB 3.37Å; E318-A382 PolarHBondContact O-N 3.39Å
319M48.4Very low58.4Low86 Ų8675 Ų7542%0.42443%0.427SS..  trans-92.8131.8174-61.6-171.6-167.900109.5C321 A432M319-C321 PolarHBondContact O-N 3.16Å; M319-A432 HydrophobicContact SD-CB 4.45Å
320D47.9Very low56Low56 Ų5678.8 Ų78.830%0.29947%0.466SS..BIsolated β-bridgetrans-72.7101.1171.2-175.92.9000109.2G322 K437D320-G322 PolarHBondContact O-N 3.13Å; D320-G322 WeakPolarHBondContact OD1-CA 3.42Å; D320-G322 PolarHBondContact OD1-N 3.14Å; D320-K437 HydrophobicContact CB-CB 4.2Å; D320-K437 PolarHBondContact O-N 2.65Å
321C44.8Very low53.2Low112 Ų11290 Ų9076%0.75751%0.508SS*.  trans-68.9-13.1174.3-64.60000112.9M319M319-C321 PolarHBondContact O-N 3.16Å
322G38.6Very low50.6Low31 Ų3196 Ų9632%0.3255%0.545SS..  trans67.3-178.9-168.300000113.4D320D320-G322 PolarHBondContact O-N 3.13Å; D320-G322 WeakPolarHBondContact OD1-CA 3.42Å; D320-G322 PolarHBondContact OD1-N 3.14Å
323V48.9Very low47.8Very low144 Ų144101.1 Ų101.187%0.87358%0.581SS**  trans-136.2151.3167.5-66.90000108.7
324E37.3Very low45Very low156 Ų156106.3 Ų106.373%0.72962%0.617SS**  trans-68.2136.7172.5-60.6-165.6146.400109.9L326E324-L326 PolarHBondContact O-N 2.85Å
325Q37.4Very low43Very low151 Ų151110.2 Ų110.271%0.70664%0.642SS**  trans-77.490.1-179.5-173.7-179.4-13.300109.9D327 G328Q325-D327 WeakPolarHBondContact CG-O 3.38Å; Q325-D327 PolarHBondContact NE2-O 3.26Å; Q325-G328 PolarHBondContact NE2-O 2.83Å
326L31.3Very low40.9Very low151 Ų151115.1 Ų115.179%0.79168%0.679SS**  trans-73.7-30.4-179.5-66.5170000113.3E324E324-L326 PolarHBondContact O-N 2.85Å
327D39.1Very low39.2Very low150 Ų150120.1 Ų120.180%0.80271%0.711SS**SBendtrans-141.2161.6-175.5-86.6-60.9000113.5Q325Q325-D327 WeakPolarHBondContact CG-O 3.38Å; Q325-D327 PolarHBondContact NE2-O 3.26Å
328G36.5Very low37.7Very low48 Ų48121 Ų12150%0.49571%0.71SS.*  trans109.1127.8168.100000114.8Q325Q325-G328 PolarHBondContact NE2-O 2.83Å
329P38.9Very low36.4Very low127 Ų127123.4 Ų123.483%0.82572%0.721SS**  trans-72.8139.1179.830.7-34.9000112R331P329-R331 PolarHBondContact O-N 3.34Å
330G47.3Very low35.3Very low80 Ų80129.6 Ų129.683%0.82574%0.74SS**SBendtrans-75.773.3-179.400000114.6
331R37Very low34.1Very low237 Ų237134.7 Ų134.789%0.89477%0.767SS**SBendtrans-172158.4148-110.1167.2-169.3-131.6-0.2114.6P329P329-R331 PolarHBondContact O-N 3.34Å
332T38.8Very low33.2Very low128 Ų128134.6 Ų134.679%0.78577%0.774SS**  trans-54.2130.1173.3490000114.6
333S32.5Very low32.7Very low111 Ų111136.9 Ų136.978%0.77680%0.797SS**  trans152.6177135.257.90000111.6
334S26.8Very low31.7Very low111 Ų111142 Ų14278%0.77680%0.801SS**  trans91.4154.2-177.3-40.10000113.8
335P32.1Very low31.3Very low113 Ų113143.5 Ų143.573%0.73481%0.808SS**  -127.2176.3-9320.92.4000113.8C337P335-C337 PolarHBondContact O-N 3.3Å
336S27.4Very low31.1Very low121 Ų121141.1 Ų141.185%0.84681%0.814SS**  trans-67.9108.1176.255.40000112.8
337C26.2Very low31.1Very low120 Ų120143.7 Ų143.781%0.81182%0.822SS**  trans-129.675.115746.60000109.6P335P335-C337 PolarHBondContact O-N 3.3Å
338E24.1Very low30.7Very low168 Ų168140.3 Ų140.379%0.78582%0.823SS**  trans-67.4135.4166.2-66.3-164.5163.500110
339Q22.9Very low30.6Very low190 Ų190146.2 Ų146.289%0.88884%0.843SS**  trans-142.6126.9161.2-158159.1-3.400108.5
340R26.1Very low30.5Very low217 Ų217144.3 Ų144.382%0.81984%0.838SS**  trans-105.3132.6179-63-175.9-172.1-177.12.4109.6
341D23Very low29.8Very low163 Ų163146.4 Ų146.487%0.87283%0.83SS**  trans-91.1152.7163-80.4-48.4000111.7
342A26.1Very low30.1Very low109 Ų109141 Ų14190%0.90183%0.826SS**  trans74.8118176.800000118.3
343G26.6Very low30.4Very low79 Ų79144.6 Ų144.681%0.81483%0.825SS**  trans155.265165.800000115.8
344R28.8Very low30.7Very low251 Ų251147.7 Ų147.795%0.94783%0.827SS**  trans-37.7137.3-178.3-80.5179.2170.6159.5-3.7115.9
345E29.4Very low31.6Very low189 Ų189154.3 Ų154.388%0.88384%0.835SS**  trans-64.7149.8160.1-62.3167.3154.900111.6
346A31.5Very low31.9Very low101 Ų101159 Ų15984%0.83584%0.838SS**  trans-153109.416400000108.7
347E32Very low32.9Very low205 Ų205161 Ų16196%0.95884%0.839SS**  trans-77.5151.9177.3-61.6-176.2124.700111.6
348G31.6Very low33.5Very low79 Ų79160.5 Ų160.581%0.81483%0.833SS**  trans-162.1128.5177.100000111.3
349D34Very low34.3Very low172 Ų172155.7 Ų155.792%0.9283%0.828SS**  trans-85.9173-165.2-156.2-1.2000114.2
350A36.3Very low34.8Very low86 Ų86158.1 Ų158.171%0.71183%0.829SS**  trans-107.3162.2-160.300000116.7
351D32.4Very low34.9Very low125 Ų125152.8 Ų152.867%0.66882%0.822SS**  trans-144119.4152.7178.125.6000111.4R353D351-R353 PolarHBondContact O-N 2.81Å
352P44.1Very low35.7Very low124 Ų124156.6 Ų156.681%0.80582%0.824SS**  trans-97.454.9-174.938.4-36.6000114.3
353R44.9Very low36.5Very low203 Ų203158.7 Ų158.777%0.76682%0.819SS**  trans-130.666.8-175.9-66.4-168.3-178.6-157.82.4117.4D351D351-R353 PolarHBondContact O-N 2.81Å
354Q38.8Very low37Very low175 Ų175164.4 Ų164.482%0.81882%0.821SS**  trans-163.8117.3141.1-113.4156.2104.100113.6
355R45.7Very low37.4Very low251 Ų251155.4 Ų155.495%0.94779%0.791SS**  trans-95.1119.4161.1-75.9-172.7175.5-162.2-0.5109.2
356R38.3Very low38.3Very low212 Ų212150.3 Ų150.380%0.878%0.775SS**  trans-135.6161.4157.1-70.7-166.3-178.5-155.90.9108.6
357D48.9Very low39.6Very low162 Ų162152 Ų15287%0.86677%0.765SS**  trans-64.7131-176.6-172.318.4000111.5
358V37.9Very low41.5Very low110 Ų110147 Ų14767%0.66774%0.738SS**  trans-135.398.3179.6-179.60000107.9R360V358-R360 PolarHBondContact O-N 3.31Å
359G41.8Very low43.8Very low66 Ų66143.4 Ų143.468%0.6870%0.7SS**  trans-53.9135.716800000110.2
360R31.6Very low46.5Very low241 Ų241135.6 Ų135.691%0.90966%0.659SS**  trans-32.8120.7-168-85.4-173.8171.8-168.5-1.9112.8V358 R362V358-R360 PolarHBondContact O-N 3.31Å; R360-R362 PolarHBondContact O-N 3.46Å
361P30Very low49.2Very low105 Ų105132 Ų13268%0.68263%0.627SS**  trans-57.6127.517624.1-33000109.1I363P361-I363 PolarHBondContact O-N 2.87Å
362R39.5Very low52.2Low243 Ų243126 Ų12692%0.91760%0.595SS**  trans-62.3110.6174.2-73.5-177.2173.5-176.9-2.6107.9R360 K364R360-R362 PolarHBondContact O-N 3.46Å; R362-K364 PolarHBondContact O-N 3.39Å; R362-K364 VanDerWaalsContact O-N 3.09Å
363I41.6Very low54.5Low153 Ų153120.5 Ų120.579%0.78556%0.559SS**  trans-58.6116178-58.5176.6000107.4P361 L365P361-I363 PolarHBondContact O-N 2.87Å; I363-L365 PolarHBondContact O-N 3.45Å
364K38.3Very low56.8Low200 Ų200110.9 Ų110.987%0.8752%0.523SS*.  trans-76.2103173.6-69.9-175.1178.2-1780107.9R362R362-K364 PolarHBondContact O-N 3.39Å; R362-K364 VanDerWaalsContact O-N 3.09Å
365L36.8Very low59.2Low61 Ų61103.1 Ų103.132%0.31949%0.487SS..  trans-63.3147.6163.8-58.4178000108.9Q303 I363Q303-L365 HydrophobicContact CB-CD1 4.33Å; I363-L365 PolarHBondContact O-N 3.45Å
366P47.4Very low60.9Low82 Ų8291.2 Ų91.253%0.53244%0.442SS..  trans-64.3160.1163.332.7-35.8000109.1N296 R368N296-P366 PolarHBondContact ND2-O 2.9Å; P366-R368 PolarHBondContact O-N 3Å
367Q59.6Low62.7Low137 Ų13781.1 Ų81.164%0.6440%0.404SS*.SBendtrans-59-46.7-178.2-73.4172.2-91.900111.7D295 N296D295-Q367 WeakPolarHBondContact CB-O 3Å; N296-Q367 WeakPolarHBondContact CB-O 3.48Å; N296-Q367 PolarHBondContact N-O 2.63Å; N296-Q367 PolarHBondContact ND2-O 3.32Å
368R72.6Confident63.8Low100 Ų10076.2 Ų76.238%0.37738%0.377SS..SBendtrans-105.7111.8175.5-61.5177.5-179.4179.4-2.9110.1D288 D295 P366 M371D288-R368 PolarHBondContact O-NH2 2.95Å; D288-R368 VanDerWaalsContact O-NH2 3.07Å; D288-R368 IonicContact OD1-CZ 3.57Å; D288-R368 VanDerWaalsContact OD1-CZ 3.24Å; D288-R368 IonicContact OD1-NH1 2.65Å; D288-R368 PolarHBondContact OD1-NH1 2.9Å; D288-R368 IonicContact OD1-NH2 3.31Å; D288-R368 PolarHBondContact OD1-NH2 3.25Å; D295-R368 HydrophobicContact CB-CG 4.12Å; P366-R368 PolarHBondContact O-N 3Å; R368-M371 HydrophobicContact CB-SD 4.21Å; R368-M371 HydrophobicContact CG-CE 4.42Å; R368-M371 HydrophobicContact CG-SD 4.4Å
369S80.1Confident65.4Low4 Ų476.9 Ų76.93%0.02837%0.371CS..  trans-144.1167.6168.764.20000111.1N296 K307 M371N296-S369 PolarHBondContact ND2-OG 3.16Å; K307-S369 WeakPolarHBondContact CE-O 3.42Å; K307-S369 PolarHBondContact NZ-O 3.06Å; K307-S369 VanDerWaalsContact NZ-O 3.14Å; S369-M371 PolarHBondContact O-N 3.37Å; S369-M371 VanDerWaalsContact O-N 3.13Å
370D89.5Confident66.2Low8 Ų874.7 Ų74.74%0.04335%0.348CS..SBendtrans6021177.2-30.3-90.3000113.2Y184 N304 K305 P306 K307 S445Y184-D370 HydrophobicContact CE1-CB 4.17Å; Y184-D370 PolarHBondContact OH-OD1 3.2Å; N304-D370 WeakPolarHBondContact CA-OD2 3.43Å; N304-D370 PolarHBondContact N-OD2 2.72Å; K305-D370 VanDerWaalsContact O-CB 3.31Å; K305-D370 WeakPolarHBondContact O-CB 3.44Å; P306-D370 CarbonylContact C-O 3.57Å; P306-D370 WeakPolarHBondContact CA-O 3.38Å; K307-D370 PolarHBondContact N-O 2.96Å; K307-D370 IonicContact NZ-OD2 2.98Å; D370-S445 PolarHBondContact N-O 3.22Å
371M92.9Very high67.7Low9 Ų964.3 Ų64.34%0.04431%0.312CS..EExtended strand (participates in β ladder)trans-100.3141.4176.1-59.3174.9176.400110.8F291 F294 D295 K307 F309 R368 S369 S445F291-M371 VanDerWaalsContact O-CE 3.29Å; F291-M371 WeakPolarHBondContact O-CE 3.43Å; F294-M371 HydrophobicContact CB-CE 4.16Å; F294-M371 VanDerWaalsContact O-CE 3.29Å; F294-M371 WeakPolarHBondContact O-CE 3.19Å; D295-M371 HydrophobicContact CB-CE 4.11Å; K307-M371 HydrophobicContact CB-CG 4.09Å; K307-M371 HydrophobicContact CD-CE 4.28Å; K307-M371 HydrophobicContact CD-CG 4.36Å; K307-M371 VanDerWaalsContact O-CA 3.32Å; K307-M371 WeakPolarHBondContact O-CA 3.19Å; F309-M371 HydrophobicContact CE2-CB 4.25Å; F309-M371 HydrophobicContact CE2-CG 4.1Å; F309-M371 HydrophobicContact CE2-SD 4.41Å; R368-M371 HydrophobicContact CB-SD 4.21Å; R368-M371 HydrophobicContact CG-CE 4.42Å; R368-M371 HydrophobicContact CG-SD 4.4Å; S369-M371 PolarHBondContact O-N 3.37Å; S369-M371 VanDerWaalsContact O-N 3.13Å; M371-S445 WeakPolarHBondContact CA-OG 3.01Å; M371-S445 WeakPolarHBondContact CB-OG 3.44Å; M371-S445 PolarHBondContact N-OG 3.33Å; M371-S445 PolarHBondContact O-N 3.31Å; M371-S445 PolarHBondContact O-OG 3.09Å
372I95.3Very high69.3Low1 Ų160.5 Ų60.51%0.00529%0.29CS..EExtended strand (participates in β ladder)trans-134.6127.8167.6-173.7168.1000109.2K307 M308 F309 L410 L414 F442 T443 L446 L450K307-I372 PolarHBondContact O-N 3.41Å; M308-I372 HydrophobicContact CB-CG2 4.37Å; M308-I372 HydrophobicContact CG-CG2 3.78Å; F309-I372 PolarHBondContact N-O 3.4Å; I372-L410 HydrophobicContact CD1-CD2 4.41Å; I372-L410 HydrophobicContact CD1-CG 4.3Å; I372-L410 HydrophobicContact CG2-CD2 3.83Å; I372-L414 HydrophobicContact CD1-CD1 3.88Å; I372-L414 HydrophobicContact CG1-CD1 4.15Å; I372-F442 HydrophobicContact CD1-CD2 4.33Å; I372-F442 HydrophobicContact CG1-CD2 4.45Å; I372-T443 WeakPolarHBondContact CA-O 3.21Å; I372-L446 HydrophobicContact CB-CD1 4.01Å; I372-L446 HydrophobicContact CB-CD2 4.21Å; I372-L446 HydrophobicContact CB-CG 4Å; I372-L446 HydrophobicContact CD1-CD1 3.84Å; I372-L446 HydrophobicContact CG1-CD1 4.49Å; I372-L446 HydrophobicContact CG2-CD1 4.13Å; I372-L446 HydrophobicContact CG2-CD2 4.21Å; I372-L446 HydrophobicContact CG2-CG 4.38Å; I372-L450 HydrophobicContact CG2-CD2 4.3Å
373C93.7Very high70.5Confident7 Ų749.7 Ų49.75%0.04725%0.252CS..EExtended strand (participates in β ladder)trans-125.2110.5-171.5-55.80000109.8F291 F309 F375 F442 T443F291-C373 HydrophobicContact CE1-CB 4.41Å; F291-C373 WeakPolarHBondContact CE1-SG 3.24Å; F291-C373 HydrophobicContact CZ-CB 4.36Å; F309-C373 HydrophobicContact CB-CB 4.15Å; F309-C373 VanDerWaalsContact CD2-SG 3.51Å; F309-C373 WeakPolarHBondContact O-CA 3.35Å; C373-F375 HydrophobicContact CB-CE2 3.67Å; C373-F375 HydrophobicContact CB-CZ 3.81Å; C373-F375 WeakPolarHBondContact O-CE2 3.3Å; C373-F442 CarbonylContact O-C 3.58Å; C373-F442 WeakPolarHBondContact O-CA 3.38Å; C373-F442 WeakPolarHBondContact O-CB 3.46Å; C373-T443 PolarHBondContact N-O 3.38Å; C373-T443 PolarHBondContact O-N 2.95Å
374G92.7Very high71.5Confident1 Ų144 Ų441%0.0122%0.222CC..EExtended strand (participates in β ladder)trans-92.9130.4170.200000111F309 I311F309-G374 PolarHBondContact O-N 3.5Å; I311-G374 PolarHBondContact N-O 2.91Å
375F89.6Confident72.8Confident13 Ų1337.2 Ų37.26%0.05719%0.191CC..EExtended strand (participates in β ladder)trans-116.1134178.6-56.2-91.9000109.5L287 F291 I311 R315 C373 S377 S440 E441 T443L287-F375 HydrophobicContact CD1-CE1 4.26Å; F291-F375 HydrophobicContact CE2-CZ 4.43Å; F291-F375 HydrophobicContact CZ-CE1 4.26Å; F291-F375 HydrophobicContact CZ-CZ 4.01Å; I311-F375 HydrophobicContact CB-CD1 3.77Å; I311-F375 HydrophobicContact CB-CE1 4.22Å; I311-F375 HydrophobicContact CG1-CD1 3.98Å; I311-F375 HydrophobicContact CG1-CE1 3.92Å; I311-F375 HydrophobicContact CG2-CD1 4.14Å; R315-F375 VanDerWaalsContact NH1-CB 3.27Å; C373-F375 HydrophobicContact CB-CE2 3.67Å; C373-F375 HydrophobicContact CB-CZ 3.81Å; C373-F375 WeakPolarHBondContact O-CE2 3.3Å; F375-S377 VanDerWaalsContact C-N 3.3Å; F375-S377 PolarHBondContact O-N 2.98Å; F375-S440 WeakPolarHBondContact O-CA 3.15Å; F375-S440 WeakPolarHBondContact O-CB 3.41Å; F375-E441 HydrophobicContact CB-CG 4.15Å; F375-E441 HydrophobicContact CD2-CG 4.18Å; F375-E441 PolarHBondContact N-O 3.49Å; F375-E441 PolarHBondContact O-N 2.96Å; F375-T443 HydrophobicContact CE2-CG2 4.44Å
376A81.4Confident74Confident0 Ų037.1 Ų37.10%019%0.191CC..SBendtrans-63.8-34.8-178.700000113.8I311 Q312 A383 F393 S440I311-A376 PolarHBondContact O-N 2.71Å; Q312-A376 VanDerWaalsContact CD-CB 3.47Å; Q312-A376 VanDerWaalsContact OE1-CB 3.26Å; A376-A383 HydrophobicContact CB-CB 4.05Å; A376-F393 HydrophobicContact CB-CB 3.64Å; A376-F393 HydrophobicContact CB-CD1 3.81Å; A376-F393 HydrophobicContact CB-CG 3.78Å; A376-S440 WeakPolarHBondContact O-CA 3.32Å
377S75.1Confident74.6Confident0 Ų037.7 Ų37.70%019%0.193CC..SBendtrans-116.5156.7178.849.50000111.5A313 R315 F375 T381 M439A313-S377 PolarHBondContact O-OG 2.89Å; R315-S377 WeakPolarHBondContact CD-O 3.41Å; R315-S377 WeakPolarHBondContact CD-OG 3.36Å; R315-S377 WeakPolarHBondContact CG-OG 3.17Å; R315-S377 PolarHBondContact NH1-O 3.3Å; F375-S377 VanDerWaalsContact C-N 3.3Å; F375-S377 PolarHBondContact O-N 2.98Å; S377-T381 WeakPolarHBondContact CB-O 3.35Å; S377-T381 PolarHBondContact OG-O 2.77Å; S377-M439 CarbonylContact C-O 3.58Å; S377-M439 WeakPolarHBondContact CA-O 3.48Å
378L72Confident74.6Confident59 Ų5938 Ų3831%0.30919%0.193SC..  trans-66.6169164.4-54.7-174.1000110.7R315 T381 M439 E441R315-L378 WeakPolarHBondContact CB-O 3.19Å; L378-T381 PolarHBondContact N-OG1 2.69Å; L378-T381 PolarHBondContact O-N 3.48Å; L378-T381 PolarHBondContact O-OG1 2.77Å; L378-M439 HydrophobicContact CD1-CB 4.15Å; L378-M439 HydrophobicContact CD1-CG 4.37Å; L378-M439 HydrophobicContact CD2-CB 4.26Å; L378-M439 HydrophobicContact CD2-CG 4.05Å; L378-M439 HydrophobicContact CG-CB 4.08Å; L378-M439 HydrophobicContact CG-CG 4.37Å; L378-M439 WeakPolarHBondContact CG-O 3.48Å; L378-M439 PolarHBondContact N-O 3.24Å; L378-M439 VanDerWaalsContact N-O 3.13Å; L378-E441 HydrophobicContact CD2-CB 3.8Å; L378-E441 HydrophobicContact CD2-CG 4.19Å
379K72Confident74Confident125 Ų12537.2 Ų37.254%0.54319%0.19SC..THydrogen-bonded Turntrans-55.8139.8164.6-69.9169.3161.5-97.60111E274 T381 E441E274-K379 HydrophobicContact CG-CB 4.41Å; E274-K379 HydrophobicContact CG-CG 4.32Å; E274-K379 WeakPolarHBondContact OE1-CG 3.36Å; E274-K379 IonicContact OE1-NZ 2.69Å; E274-K379 PolarHBondContact OE1-NZ 2.82Å; K379-T381 PolarHBondContact O-N 2.78Å; K379-E441 PolarHBondContact N-OE2 2.98Å
380G59.5Low73.7Confident19 Ų1937 Ų3720%0.19619%0.188CC..THydrogen-bonded Turntrans81.6-23.2179.300000115.3R315 G316 D317 E318R315-G380 WeakPolarHBondContact O-CA 3.22Å; R315-G380 PolarHBondContact O-N 3.43Å; G316-G380 CarbonylContact C-O 3.58Å; G316-G380 VanDerWaalsContact C-O 3.25Å; G316-G380 WeakPolarHBondContact CA-O 3.43Å; D317-G380 PolarHBondContact N-O 2.93Å; E318-G380 WeakPolarHBondContact CB-O 3.25Å; E318-G380 PolarHBondContact N-O 2.73Å
381T61.5Low73.4Confident23 Ų2336.7 Ų36.714%0.14119%0.186CC..BIsolated β-bridgetrans-98.3155.1-17165.20000115R315 G316 E318 S377 L378 K379R315-T381 PolarHBondContact N-O 2.7Å; G316-T381 CarbonylContact O-C 3.56Å; E318-T381 CarbonylContact O-C 3.5Å; E318-T381 WeakPolarHBondContact O-CA 3.42Å; E318-T381 WeakPolarHBondContact O-CB 3.37Å; S377-T381 WeakPolarHBondContact CB-O 3.35Å; S377-T381 PolarHBondContact OG-O 2.77Å; L378-T381 PolarHBondContact N-OG1 2.69Å; L378-T381 PolarHBondContact O-N 3.48Å; L378-T381 PolarHBondContact O-OG1 2.77Å; K379-T381 PolarHBondContact O-N 2.78Å
382A65.3Low73Confident26 Ų2637.4 Ų37.422%0.21519%0.189CC..PPolyproline II helixtrans-74.6147.5172.300000111.7G316 E318G316-A382 PolarHBondContact O-N 3.1Å; E318-A382 PolarHBondContact O-N 3.39Å
383A63.6Low72.7Confident16 Ų1637.4 Ų37.413%0.13219%0.189CC..PPolyproline II helixtrans-100.8131.7176.900000111.4A313 C314 A376 E438A313-A383 WeakPolarHBondContact O-CB 3.23Å; C314-A383 PolarHBondContact SG-N 3.27Å; C314-A383 VanDerWaalsContact SG-N 3.37Å; A376-A383 HydrophobicContact CB-CB 4.05Å; A383-E438 WeakPolarHBondContact CA-OE1 3.42Å
384M61.7Low72.6Confident32 Ų3237 Ų3716%0.15819%0.186CC..PPolyproline II helixtrans-90.4149.1-169.7-69.9-60-63.700113.4S391 W392 H433 C436 E438M384-S391 PolarHBondContact O-OG 3.46Å; M384-W392 HydrophobicContact CB-CD2 4.29Å; M384-W392 HydrophobicContact CB-CE3 4.3Å; M384-H433 HydrophobicContact CE-CB 4.31Å; M384-C436 VanDerWaalsContact CE-SG 3.6Å; M384-E438 HydrophobicContact CB-CB 4.2Å; M384-E438 HydrophobicContact CB-CG 4.45Å; M384-E438 HydrophobicContact CG-CB 4.07Å; M384-E438 PolarHBondContact N-OE1 3.25Å
385R66.9Low72.4Confident58 Ų5837.6 Ų37.622%0.21919%0.189CC..EExtended strand (participates in β ladder)trans-155.1132.9-171.3-153.3156.56970.332113R213 K214 S391R213-R385 PolarHBondContact O-NH1 3.38Å; R213-R385 PolarHBondContact O-NH2 2.86Å; K214-R385 VanDerWaalsContact O-CZ 3.28Å; K214-R385 PolarHBondContact O-NH1 3.13Å; K214-R385 PolarHBondContact O-NH2 3.45Å; R385-S391 WeakPolarHBondContact CD-OG 3.34Å; R385-S391 WeakPolarHBondContact CG-OG 3.43Å
386N62.7Low72.5Confident59 Ų5938 Ų3832%0.31619%0.19SC..EExtended strand (participates in β ladder)trans-96.2129.2174.7-177.9-71.9000109.7K388 R389 G390N386-K388 PolarHBondContact O-N 3.04Å; N386-K388 PolarHBondContact OD1-N 3.43Å; N386-R389 HydrophobicContact CB-CB 4.1Å; N386-R389 PolarHBondContact O-N 3.03Å; N386-R389 PolarHBondContact OD1-N 2.97Å; N386-G390 WeakPolarHBondContact CB-O 3.25Å; N386-G390 PolarHBondContact N-O 3.19Å; N386-G390 WeakPolarHBondContact O-CA 3.49Å; N386-G390 PolarHBondContact O-N 3.27Å
387T59.3Low73.2Confident94 Ų9438 Ų3858%0.57719%0.191SC*.THydrogen-bonded Turntrans-68.9-14.7-173.750.40000115.1K214K214-T387 HydrophobicContact CB-CG2 4.3Å
388K59Low74.1Confident145 Ų14538.1 Ų38.163%0.6319%0.191SC*.THydrogen-bonded Turntrans-103.6-37.8172.3-67.1-176.7174.7-175.20113.3D161 N386D161-K388 IonicContact OD2-NZ 3.87Å; D161-K388 PolarHBondContact OD2-NZ 2.76Å; N386-K388 PolarHBondContact O-N 3.04Å; N386-K388 PolarHBondContact OD1-N 3.43Å
389R61.3Low75Confident83 Ų8336 Ų3631%0.31318%0.181SC..THydrogen-bonded Turntrans-100-9.6-167.9-55.1-179.770.1-154.22.7113.9D161 N386 Q395D161-R389 WeakPolarHBondContact O-CG 3.46Å; N386-R389 HydrophobicContact CB-CB 4.1Å; N386-R389 PolarHBondContact O-N 3.03Å; N386-R389 PolarHBondContact OD1-N 2.97Å; R389-Q395 VanDerWaalsContact CB-NE2 3.31Å; R389-Q395 PolarHBondContact O-NE2 3.41Å
390G71.8Confident76.1Confident0 Ų030.1 Ų30.10%016%0.155CC..EExtended strand (participates in β ladder)trans86-167.4-170.700000113.4D219 N386 Q395D219-G390 VanDerWaalsContact OD1-CA 3.25Å; D219-G390 WeakPolarHBondContact OD1-CA 3.4Å; N386-G390 WeakPolarHBondContact CB-O 3.25Å; N386-G390 PolarHBondContact N-O 3.19Å; N386-G390 WeakPolarHBondContact O-CA 3.49Å; N386-G390 PolarHBondContact O-N 3.27Å; G390-Q395 PolarHBondContact O-NE2 2.83Å
391S83.3Confident77.7Confident0 Ų029.2 Ų29.20%015%0.146CC..EExtended strand (participates in β ladder)trans-76146.6178.6-101.40000113.3D219 Q312 M384 R385 I394 Q395D219-S391 PolarHBondContact OD1-N 2.84Å; D219-S391 PolarHBondContact OD2-N 2.91Å; Q312-S391 PolarHBondContact NE2-OG 2.93Å; Q312-S391 PolarHBondContact OE1-OG 2.85Å; M384-S391 PolarHBondContact O-OG 3.46Å; R385-S391 WeakPolarHBondContact CD-OG 3.34Å; R385-S391 WeakPolarHBondContact CG-OG 3.43Å; S391-I394 PolarHBondContact O-N 3.29Å; S391-Q395 WeakPolarHBondContact O-CB 3.42Å; S391-Q395 VanDerWaalsContact O-CG 3.25Å; S391-Q395 WeakPolarHBondContact O-CG 3.18Å; S391-Q395 PolarHBondContact O-N 2.8Å; S391-Q395 PolarHBondContact O-NE2 2.82Å
392W84.8Confident79.3Confident24 Ų2428.4 Ų28.49%0.09114%0.14CC..Hα-helixtrans-63.5-44.9179.3-66.52.6000111.4M384 I394 Q395 E396 R424 E438M384-W392 HydrophobicContact CB-CD2 4.29Å; M384-W392 HydrophobicContact CB-CE3 4.3Å; W392-I394 PolarHBondContact O-N 3.45Å; W392-Q395 PolarHBondContact O-N 3.24Å; W392-E396 PolarHBondContact O-N 3.45Å; W392-R424 HydrophobicContact CD2-CB 4.12Å; W392-R424 HydrophobicContact CE3-CB 3.65Å; W392-R424 HydrophobicContact CE3-CG 4.44Å; W392-R424 VanDerWaalsContact CG-NH1 3.29Å; W392-R424 HydrophobicContact CH2-CB 3.97Å; W392-R424 HydrophobicContact CZ2-CB 4.39Å; W392-R424 HydrophobicContact CZ3-CB 3.57Å; W392-E438 WeakPolarHBondContact CB-OE2 3.04Å; W392-E438 HydrophobicContact CE3-CB 3.85Å; W392-E438 HydrophobicContact CZ3-CB 3.92Å
393F90Very high80.5Confident1 Ų130.2 Ų30.20%0.00415%0.146CC..Hα-helixtrans-58.2-44.8175.4175.5-105.6000113.1F310 A376 E396 L397 V417 I421F310-F393 HydrophobicContact CB-CE1 4.42Å; F310-F393 HydrophobicContact CD1-CZ 4.34Å; A376-F393 HydrophobicContact CB-CB 3.64Å; A376-F393 HydrophobicContact CB-CD1 3.81Å; A376-F393 HydrophobicContact CB-CG 3.78Å; F393-E396 PolarHBondContact O-N 3.14Å; F393-L397 HydrophobicContact CE1-CD2 4.42Å; F393-L397 WeakPolarHBondContact O-CB 3.41Å; F393-L397 PolarHBondContact O-N 3.49Å; F393-V417 HydrophobicContact CD2-CG1 3.82Å; F393-V417 HydrophobicContact CE2-CG1 4.05Å; F393-I421 HydrophobicContact CB-CD1 4.03Å; F393-I421 HydrophobicContact CD2-CD1 4.01Å
394I91.8Very high82Confident0 Ų031.2 Ų31.20%015%0.148CC..Hα-helixtrans-68.3-38.8177.8-57.3-54.5000112.2D219 V222 L223 L269 Q312 S391 W392 N398D219-I394 HydrophobicContact CB-CB 4.33Å; D219-I394 HydrophobicContact CB-CG1 4.22Å; D219-I394 HydrophobicContact CB-CG2 4Å; D219-I394 WeakPolarHBondContact OD1-CB 3.18Å; V222-I394 HydrophobicContact CG1-CG2 4.14Å; L223-I394 HydrophobicContact CD1-CD1 4.17Å; L223-I394 HydrophobicContact CD1-CG2 4.48Å; L223-I394 HydrophobicContact CD2-CD1 4.4Å; L223-I394 HydrophobicContact CD2-CG2 3.91Å; L223-I394 HydrophobicContact CG-CG2 3.92Å; L269-I394 HydrophobicContact CD2-CD1 3.99Å; L269-I394 HydrophobicContact CD2-CG1 4.42Å; Q312-I394 HydrophobicContact CB-CD1 4.25Å; Q312-I394 HydrophobicContact CB-CG1 4.31Å; Q312-I394 HydrophobicContact CG-CG1 4.27Å; S391-I394 PolarHBondContact O-N 3.29Å; W392-I394 PolarHBondContact O-N 3.45Å; I394-N398 VanDerWaalsContact O-CB 3.25Å; I394-N398 WeakPolarHBondContact O-CB 3.41Å; I394-N398 PolarHBondContact O-N 3.43Å
395Q88.3Confident83.6Confident13 Ų1329.8 Ų29.86%0.06114%0.141CC..Hα-helixtrans-61.4-47.7173.6-73.1163.730.900112.1R389 G390 S391 W392 N398 T399R389-Q395 VanDerWaalsContact CB-NE2 3.31Å; R389-Q395 PolarHBondContact O-NE2 3.41Å; G390-Q395 PolarHBondContact O-NE2 2.83Å; S391-Q395 WeakPolarHBondContact O-CB 3.42Å; S391-Q395 VanDerWaalsContact O-CG 3.25Å; S391-Q395 WeakPolarHBondContact O-CG 3.18Å; S391-Q395 PolarHBondContact O-N 2.8Å; S391-Q395 PolarHBondContact O-NE2 2.82Å; W392-Q395 PolarHBondContact O-N 3.24Å; Q395-N398 PolarHBondContact O-N 3.03Å; Q395-T399 WeakPolarHBondContact O-CB 3.33Å; Q395-T399 PolarHBondContact O-N 2.91Å; Q395-T399 PolarHBondContact O-OG1 3.44Å
396E92.1Very high84.8Confident20 Ų2031.7 Ų31.79%0.09315%0.148CC..Hα-helixtrans-71.8-38-178.9-70.2-52.1153.400112.3W392 F393 T399 A400 V417 R420 I421 R424W392-E396 PolarHBondContact O-N 3.45Å; F393-E396 PolarHBondContact O-N 3.14Å; E396-T399 PolarHBondContact O-N 3.02Å; E396-T399 VanDerWaalsContact O-N 3.16Å; E396-A400 WeakPolarHBondContact O-CB 3.29Å; E396-A400 PolarHBondContact O-N 3.28Å; E396-V417 HydrophobicContact CB-CB 4.47Å; E396-V417 HydrophobicContact CB-CG1 4.02Å; E396-V417 HydrophobicContact CB-CG2 4.29Å; E396-R420 HydrophobicContact CG-CB 4.02Å; E396-R420 WeakPolarHBondContact OE2-CD 3.4Å; E396-R420 IonicContact OE2-CZ 3.02Å; E396-R420 IonicContact OE2-NE 3.89Å; E396-R420 IonicContact OE2-NH1 3.86Å; E396-R420 PolarHBondContact OE2-NH1 3.25Å; E396-R420 VanDerWaalsContact OE2-NH1 3.11Å; E396-I421 HydrophobicContact CB-CD1 4.47Å; E396-I421 HydrophobicContact CB-CG1 4.28Å; E396-I421 HydrophobicContact CG-CG1 3.98Å; E396-R424 IonicContact OE1-CZ 2.67Å; E396-R424 VanDerWaalsContact OE1-CZ 3.23Å; E396-R424 IonicContact OE1-NE 3.27Å; E396-R424 PolarHBondContact OE1-NE 2.75Å; E396-R424 IonicContact OE1-NH2 3.27Å; E396-R424 PolarHBondContact OE1-NH2 3.15Å
397L94.4Very high86.3Confident1 Ų131.2 Ų31.21%0.00515%0.146CC..Hα-helixtrans-58.6-48.5172179.463.6000111.2L223 F310 F393 T399 A400 L401 L414 V417L223-L397 HydrophobicContact CD2-CD2 4.4Å; F310-L397 HydrophobicContact CB-CD2 4.2Å; F310-L397 HydrophobicContact CD1-CD1 4.23Å; F310-L397 HydrophobicContact CD1-CD2 3.47Å; F310-L397 VanDerWaalsContact CD1-CD2 3.47Å; F310-L397 HydrophobicContact CD2-CD2 4.26Å; F310-L397 HydrophobicContact CE1-CD1 3.79Å; F310-L397 HydrophobicContact CE1-CD2 3.84Å; F310-L397 HydrophobicContact CE1-CG 4.48Å; F310-L397 HydrophobicContact CG-CD2 3.71Å; F310-L397 HydrophobicContact CZ-CD1 4.31Å; F310-L397 HydrophobicContact CZ-CD2 4.37Å; F393-L397 HydrophobicContact CE1-CD2 4.42Å; F393-L397 WeakPolarHBondContact O-CB 3.41Å; F393-L397 PolarHBondContact O-N 3.49Å; L397-T399 VanDerWaalsContact C-N 3.29Å; L397-T399 PolarHBondContact O-N 2.96Å; L397-A400 PolarHBondContact O-N 3.23Å; L397-L401 HydrophobicContact CD1-CD1 3.97Å; L397-L401 HydrophobicContact CD1-CG 4.17Å; L397-L401 HydrophobicContact CG-CD1 3.92Å; L397-L401 HydrophobicContact CG-CG 4.49Å; L397-L401 WeakPolarHBondContact O-CB 3.22Å; L397-L401 WeakPolarHBondContact O-CG 3.35Å; L397-L401 PolarHBondContact O-N 3.25Å; L397-L414 HydrophobicContact CD1-CD2 4.04Å; L397-V417 HydrophobicContact CB-CG2 4.48Å
398N94.6Very high87.9Confident2 Ų228 Ų281%0.01113%0.126CC..Hα-helixtrans-57.2-42.2173.8171.376.2000112I164 V222 I394 Q395 R402I164-N398 PolarHBondContact O-ND2 3.05Å; I164-N398 VanDerWaalsContact O-ND2 3.1Å; V222-N398 HydrophobicContact CG1-CB 3.48Å; V222-N398 VanDerWaalsContact CG1-CB 3.48Å; V222-N398 VanDerWaalsContact CG1-CG 3.47Å; I394-N398 VanDerWaalsContact O-CB 3.25Å; I394-N398 WeakPolarHBondContact O-CB 3.41Å; I394-N398 PolarHBondContact O-N 3.43Å; Q395-N398 PolarHBondContact O-N 3.03Å; N398-R402 WeakPolarHBondContact O-CB 3.49Å; N398-R402 VanDerWaalsContact O-CG 3.26Å; N398-R402 WeakPolarHBondContact O-CG 3.48Å; N398-R402 PolarHBondContact O-N 2.73Å; N398-R402 WeakPolarHBondContact OD1-CD 3.48Å; N398-R402 PolarHBondContact OD1-NE 2.74Å
399T92.2Very high89.6Confident16 Ų1622.7 Ų22.710%0.09810%0.103CC..Hα-helixtrans-70.8-41.9-178.2-53.90000111.9I164 Q395 E396 L397 L403I164-T399 HydrophobicContact CD1-CG2 3.71Å; Q395-T399 WeakPolarHBondContact O-CB 3.33Å; Q395-T399 PolarHBondContact O-N 2.91Å; Q395-T399 PolarHBondContact O-OG1 3.44Å; E396-T399 PolarHBondContact O-N 3.02Å; E396-T399 VanDerWaalsContact O-N 3.16Å; L397-T399 VanDerWaalsContact C-N 3.29Å; L397-T399 PolarHBondContact O-N 2.96Å; T399-L403 HydrophobicContact CG2-CD1 4Å; T399-L403 VanDerWaalsContact O-CG 3.32Å; T399-L403 WeakPolarHBondContact O-CG 3.46Å; T399-L403 PolarHBondContact O-N 2.97Å
400A93.5Very high91.3Very high0 Ų018.8 Ų18.80%09%0.088CC..Hα-helixtrans-63.5-47.5173.700000111.3E396 L397 R402 L403 H404 M413 V417E396-A400 WeakPolarHBondContact O-CB 3.29Å; E396-A400 PolarHBondContact O-N 3.28Å; L397-A400 PolarHBondContact O-N 3.23Å; A400-R402 PolarHBondContact O-N 3.21Å; A400-L403 PolarHBondContact O-N 3.04Å; A400-H404 VanDerWaalsContact O-CB 3.28Å; A400-H404 WeakPolarHBondContact O-CB 3.39Å; A400-H404 PolarHBondContact O-N 3.45Å; A400-M413 HydrophobicContact CB-CB 4.36Å; A400-V417 HydrophobicContact CB-CG2 3.8Å
401L94.7Very high92.4Very high1 Ų120.1 Ų20.11%0.00510%0.098CC..Hα-helixtrans-61.7-41.7178.2-71.7172.4000112.7V226 F227 L230 L397 A405 L410 M413 L452V226-L401 HydrophobicContact CG1-CD1 4.27Å; V226-L401 HydrophobicContact CG2-CB 3.92Å; V226-L401 HydrophobicContact CG2-CD1 4.4Å; F227-L401 HydrophobicContact CE1-CD1 4.07Å; F227-L401 HydrophobicContact CZ-CD1 4.27Å; L230-L401 HydrophobicContact CD1-CB 4.46Å; L230-L401 HydrophobicContact CD1-CD1 4.39Å; L230-L401 HydrophobicContact CD1-CD2 4.33Å; L397-L401 HydrophobicContact CD1-CD1 3.97Å; L397-L401 HydrophobicContact CD1-CG 4.17Å; L397-L401 HydrophobicContact CG-CD1 3.92Å; L397-L401 HydrophobicContact CG-CG 4.49Å; L397-L401 WeakPolarHBondContact O-CB 3.22Å; L397-L401 WeakPolarHBondContact O-CG 3.35Å; L397-L401 PolarHBondContact O-N 3.25Å; L401-A405 WeakPolarHBondContact O-CB 3.48Å; L401-A405 PolarHBondContact O-N 3.29Å; L401-L410 HydrophobicContact CD2-CD1 4.31Å; L401-M413 HydrophobicContact CD2-CE 3.98Å; L401-M413 HydrophobicContact CD2-SD 4.22Å; L401-L452 HydrophobicContact CD2-CD1 3.57Å
402R93.6Very high92.9Very high5 Ų524 Ų242%0.01912%0.118CC..Hα-helixtrans-66-38.9-179.3-78172.9-179.5-68.2-13.3113.5I164 T166 V168 L169 V226 E229 N398 A400I164-R402 PolarHBondContact O-NE 2.93Å; T166-R402 VanDerWaalsContact O-CD 3.29Å; T166-R402 WeakPolarHBondContact O-CD 3.4Å; T166-R402 PolarHBondContact O-NH1 2.76Å; V168-R402 HydrophobicContact CG2-CG 3.89Å; L169-R402 PolarHBondContact N-O 3.33Å; L169-R402 VanDerWaalsContact N-O 3.12Å; V226-R402 HydrophobicContact CG2-CG 3.95Å; E229-R402 VanDerWaalsContact CD-NH1 3.25Å; E229-R402 IonicContact OE1-CZ 2.84Å; E229-R402 IonicContact OE1-NH1 2.74Å; E229-R402 PolarHBondContact OE1-NH1 3.38Å; E229-R402 IonicContact OE1-NH2 3.77Å; E229-R402 PolarHBondContact OE1-NH2 3.49Å; E229-R402 IonicContact OE2-NH1 3.15Å; E229-R402 PolarHBondContact OE2-NH1 3.17Å; N398-R402 WeakPolarHBondContact O-CB 3.49Å; N398-R402 VanDerWaalsContact O-CG 3.26Å; N398-R402 WeakPolarHBondContact O-CG 3.48Å; N398-R402 PolarHBondContact O-N 2.73Å; N398-R402 WeakPolarHBondContact OD1-CD 3.48Å; N398-R402 PolarHBondContact OD1-NE 2.74Å; A400-R402 PolarHBondContact O-N 3.21Å
403L91.7Very high93.4Very high64 Ų6422.9 Ų22.934%0.33511%0.114SC..Hα-helixtrans-85.4-41.5-176.8-62.4174.5000112.6T399 A400T399-L403 HydrophobicContact CG2-CD1 4Å; T399-L403 VanDerWaalsContact O-CG 3.32Å; T399-L403 WeakPolarHBondContact O-CG 3.46Å; T399-L403 PolarHBondContact O-N 2.97Å; A400-L403 PolarHBondContact O-N 3.04Å
404H94.5Very high93.7Very high38 Ų3822.9 Ų22.918%0.17611%0.114CC..Hα-helixtrans-118.8-9.1-158.8-52.6-38.2000115A400 R406 D407 T408 M413 Q416 R420A400-H404 VanDerWaalsContact O-CB 3.28Å; A400-H404 WeakPolarHBondContact O-CB 3.39Å; A400-H404 PolarHBondContact O-N 3.45Å; H404-R406 PolarHBondContact O-N 3.37Å; H404-D407 PolarHBondContact O-N 2.96Å; H404-D407 VanDerWaalsContact O-N 3.09Å; H404-T408 WeakPolarHBondContact O-CB 3.34Å; H404-T408 PolarHBondContact O-N 2.9Å; H404-M413 HydrophobicContact CB-CG 4.08Å; H404-M413 HydrophobicContact CB-SD 3.98Å; H404-Q416 PolarHBondContact CD2-OE1 3.41Å; H404-Q416 PolarHBondContact NE2-OE1 3.16Å; H404-R420 PolarHBondContact NE2-NH2 2.79Å
405A94.4Very high93.8Very high1 Ų126.5 Ų26.51%0.00814%0.137CC..THydrogen-bonded Turntrans-62.3-12.1178.400000114L230 L401 M413 L452 P454L230-A405 HydrophobicContact CD2-CB 3.98Å; L401-A405 WeakPolarHBondContact O-CB 3.48Å; L401-A405 PolarHBondContact O-N 3.29Å; A405-M413 HydrophobicContact CB-CE 4.22Å; A405-M413 HydrophobicContact CB-SD 4.15Å; A405-M413 PolarHBondContact N-SD 3.42Å; A405-L452 HydrophobicContact CB-CB 4.27Å; A405-L452 HydrophobicContact CB-CD1 4.14Å; A405-P454 HydrophobicContact CB-CG 4.39Å; A405-P454 WeakPolarHBondContact O-CD 3.21Å
406R93.4Very high93.9Very high99 Ų9928.8 Ų28.837%0.37415%0.147SC..THydrogen-bonded Turntrans-79.3-23.5176.460159.7-154.9-1683.2115L169 P170 F175 H404 P454L169-R406 HydrophobicContact CB-CG 4.28Å; P170-R406 WeakPolarHBondContact O-CB 3.43Å; F175-R406 WeakPolarHBondContact CD1-O 3.4Å; H404-R406 PolarHBondContact O-N 3.37Å; R406-P454 HydrophobicContact CB-CG 3.89Å
407D92.7Very high94Very high49 Ų4927.9 Ų27.926%0.26214%0.143SC..THydrogen-bonded Turntrans-144.9-10.4-167.255.520.5000114.4F175 H404F175-D407 HydrophobicContact CD2-CB 4.4Å; F175-D407 HydrophobicContact CE2-CB 4.23Å; F175-D407 WeakPolarHBondContact CE2-O 3.35Å; F175-D407 VanDerWaalsContact CZ-C 3.5Å; F175-D407 HydrophobicContact CZ-CB 4.46Å; F175-D407 WeakPolarHBondContact CZ-O 3.2Å; H404-D407 PolarHBondContact O-N 2.96Å; H404-D407 VanDerWaalsContact O-N 3.09Å
408T94.6Very high93.8Very high25 Ų2529 Ų2915%0.15315%0.149CC..SBendtrans-122.6139.5-174.8-52.60000110.5H404 D412 M413H404-T408 WeakPolarHBondContact O-CB 3.34Å; H404-T408 PolarHBondContact O-N 2.9Å; T408-D412 HydrophobicContact CG2-CB 3.63Å; T408-M413 HydrophobicContact CG2-CG 3.74Å
409H93.8Very high93.4Very high35 Ų3531.2 Ų31.216%0.16217%0.168CC..  trans-81156.3176.463.754.4000111.8S411 D412 M413 D449 L450 Y451H409-S411 VanDerWaalsContact C-N 3.32Å; H409-S411 PolarHBondContact O-N 3.16Å; H409-S411 VanDerWaalsContact O-N 3.16Å; H409-D412 IonicContact CE1-OD1 3.58Å; H409-D412 PolarHBondContact CE1-OD1 2.74Å; H409-D412 IonicContact CE1-OD2 2.78Å; H409-D412 PolarHBondContact ND1-N 3.19Å; H409-D412 IonicContact ND1-OD1 2.77Å; H409-D412 IonicContact NE2-OD1 3.98Å; H409-D412 PolarHBondContact O-N 3.11Å; H409-D412 VanDerWaalsContact O-N 3.11Å; H409-M413 PolarHBondContact O-N 2.98Å; H409-M413 VanDerWaalsContact O-N 3.11Å; H409-D449 HydrophobicContact CB-CB 4.29Å; H409-D449 IonicContact CD2-OD1 3.96Å; H409-L450 CarbonylContact C-O 3.59Å; H409-L450 VanDerWaalsContact CA-O 3.31Å; H409-L450 WeakPolarHBondContact CA-O 3.32Å; H409-Y451 HydrophobicContact CB-CD1 3.94Å; H409-Y451 HydrophobicContact CB-CD2 4.37Å; H409-Y451 HydrophobicContact CB-CE1 3.7Å; H409-Y451 HydrophobicContact CB-CE2 4.15Å; H409-Y451 HydrophobicContact CB-CG 4.27Å; H409-Y451 VanDerWaalsContact N-CE1 3.31Å
410L96.3Very high93.1Very high0 Ų033 Ų330%017%0.172CC..Hα-helixtrans-58.7-35.8-168-173.459.4000114.7M308 F310 I372 L401 D412 M413 L414 L450M308-L410 HydrophobicContact CG-CD2 3.64Å; M308-L410 HydrophobicContact SD-CD2 3.65Å; F310-L410 HydrophobicContact CZ-CD1 4.46Å; F310-L410 HydrophobicContact CZ-CD2 4.24Å; I372-L410 HydrophobicContact CD1-CD2 4.41Å; I372-L410 HydrophobicContact CD1-CG 4.3Å; I372-L410 HydrophobicContact CG2-CD2 3.83Å; L401-L410 HydrophobicContact CD2-CD1 4.31Å; L410-D412 PolarHBondContact O-N 2.73Å; L410-M413 HydrophobicContact CB-CE 4.3Å; L410-M413 HydrophobicContact CD1-CB 4.48Å; L410-M413 HydrophobicContact CD1-CE 3.94Å; L410-M413 PolarHBondContact O-N 3.02Å; L410-L414 HydrophobicContact CD1-CG 4.37Å; L410-L414 HydrophobicContact CG-CD1 4.29Å; L410-L414 HydrophobicContact CG-CG 4.49Å; L410-L414 WeakPolarHBondContact O-CG 3.36Å; L410-L414 PolarHBondContact O-N 3.45Å; L410-L450 HydrophobicContact CB-CB 4.37Å; L410-L450 HydrophobicContact CB-CD2 4.27Å; L410-L450 HydrophobicContact CB-CG 4.26Å; L410-L450 HydrophobicContact CD2-CD2 3.92Å; L410-L450 PolarHBondContact N-O 3.29Å
411S95.1Very high92.6Very high28 Ų2833 Ų3320%0.19617%0.172CC..Hα-helixtrans-57.7-47.5176.6-43.90000112.3H409 L414 V415H409-S411 VanDerWaalsContact C-N 3.32Å; H409-S411 PolarHBondContact O-N 3.16Å; H409-S411 VanDerWaalsContact O-N 3.16Å; S411-L414 WeakPolarHBondContact O-CB 3.32Å; S411-L414 PolarHBondContact O-N 2.94Å; S411-L414 VanDerWaalsContact O-N 3.14Å; S411-V415 WeakPolarHBondContact O-CG2 2.92Å; S411-V415 PolarHBondContact O-N 2.86Å
412D95.3Very high92Very high81 Ų8139.5 Ų39.543%0.43320%0.201SC..Hα-helixtrans-72.1-32.3179.1-84.120.9000112.3T408 H409 L410 L414 V415 Q416T408-D412 HydrophobicContact CG2-CB 3.63Å; H409-D412 IonicContact CE1-OD1 3.58Å; H409-D412 PolarHBondContact CE1-OD1 2.74Å; H409-D412 IonicContact CE1-OD2 2.78Å; H409-D412 PolarHBondContact ND1-N 3.19Å; H409-D412 IonicContact ND1-OD1 2.77Å; H409-D412 IonicContact NE2-OD1 3.98Å; H409-D412 PolarHBondContact O-N 3.11Å; H409-D412 VanDerWaalsContact O-N 3.11Å; L410-D412 PolarHBondContact O-N 2.73Å; D412-L414 VanDerWaalsContact C-N 3.28Å; D412-L414 PolarHBondContact O-N 3.38Å; D412-V415 PolarHBondContact O-N 2.76Å; D412-Q416 WeakPolarHBondContact O-CG 3.5Å; D412-Q416 PolarHBondContact O-N 3.09Å
413M95.7Very high91.3Very high1 Ų146.8 Ų46.81%0.00524%0.235CC..Hα-helixtrans-61.2-38.9168.5-69-165.5-77.100111.2A400 L401 H404 A405 T408 H409 L410 Q416 V417 L452A400-M413 HydrophobicContact CB-CB 4.36Å; L401-M413 HydrophobicContact CD2-CE 3.98Å; L401-M413 HydrophobicContact CD2-SD 4.22Å; H404-M413 HydrophobicContact CB-CG 4.08Å; H404-M413 HydrophobicContact CB-SD 3.98Å; A405-M413 HydrophobicContact CB-CE 4.22Å; A405-M413 HydrophobicContact CB-SD 4.15Å; A405-M413 PolarHBondContact N-SD 3.42Å; T408-M413 HydrophobicContact CG2-CG 3.74Å; H409-M413 PolarHBondContact O-N 2.98Å; H409-M413 VanDerWaalsContact O-N 3.11Å; L410-M413 HydrophobicContact CB-CE 4.3Å; L410-M413 HydrophobicContact CD1-CB 4.48Å; L410-M413 HydrophobicContact CD1-CE 3.94Å; L410-M413 PolarHBondContact O-N 3.02Å; M413-Q416 PolarHBondContact O-N 3.11Å; M413-V417 WeakPolarHBondContact O-CG2 3.32Å; M413-V417 PolarHBondContact O-N 3.03Å; M413-L452 HydrophobicContact CE-CD1 4.23Å
414L95.2Very high90.5Very high1 Ų145.9 Ų45.91%0.00523%0.227CC..Hα-helixtrans-72.1-33.6175.2-67.9173.3000112.9F310 I372 L397 L410 S411 D412 Q416 V417 N418 F442F310-L414 HydrophobicContact CE1-CD2 4.38Å; I372-L414 HydrophobicContact CD1-CD1 3.88Å; I372-L414 HydrophobicContact CG1-CD1 4.15Å; L397-L414 HydrophobicContact CD1-CD2 4.04Å; L410-L414 HydrophobicContact CD1-CG 4.37Å; L410-L414 HydrophobicContact CG-CD1 4.29Å; L410-L414 HydrophobicContact CG-CG 4.49Å; L410-L414 WeakPolarHBondContact O-CG 3.36Å; L410-L414 PolarHBondContact O-N 3.45Å; S411-L414 WeakPolarHBondContact O-CB 3.32Å; S411-L414 PolarHBondContact O-N 2.94Å; S411-L414 VanDerWaalsContact O-N 3.14Å; D412-L414 VanDerWaalsContact C-N 3.28Å; D412-L414 PolarHBondContact O-N 3.38Å; L414-Q416 VanDerWaalsContact C-N 3.3Å; L414-Q416 PolarHBondContact O-N 3.15Å; L414-V417 WeakPolarHBondContact O-CB 3.26Å; L414-V417 PolarHBondContact O-N 3.39Å; L414-N418 PolarHBondContact O-N 3.32Å; L414-N418 PolarHBondContact O-OD1 3.43Å; L414-F442 HydrophobicContact CB-CB 4.47Å; L414-F442 HydrophobicContact CB-CD1 3.58Å; L414-F442 HydrophobicContact CB-CD2 4.46Å; L414-F442 HydrophobicContact CB-CE1 3.82Å; L414-F442 HydrophobicContact CB-CG 3.94Å; L414-F442 HydrophobicContact CB-CZ 4.36Å; L414-F442 HydrophobicContact CD1-CB 3.85Å; L414-F442 HydrophobicContact CD1-CD1 4.39Å; L414-F442 HydrophobicContact CD1-CD2 4.06Å; L414-F442 HydrophobicContact CD1-CG 3.86Å
415V93.8Very high89.3Confident77 Ų7748.3 Ų48.347%0.46724%0.238SC..Hα-helixtrans-60.9-39.6168.8174.10000111.1S411 D412 N418 A419 F442S411-V415 WeakPolarHBondContact O-CG2 2.92Å; S411-V415 PolarHBondContact O-N 2.86Å; D412-V415 PolarHBondContact O-N 2.76Å; V415-N418 PolarHBondContact O-N 2.92Å; V415-A419 PolarHBondContact O-N 2.87Å; V415-F442 HydrophobicContact CG2-CE1 3.84Å; V415-F442 HydrophobicContact CG2-CZ 3.93Å
416Q91.6Very high87.9Confident61 Ų6148.4 Ų48.429%0.28524%0.24SC..Hα-helixtrans-69.3-35.1174.5-70.6-175.461.100113.3H404 D412 M413 L414 A419 R420H404-Q416 PolarHBondContact CD2-OE1 3.41Å; H404-Q416 PolarHBondContact NE2-OE1 3.16Å; D412-Q416 WeakPolarHBondContact O-CG 3.5Å; D412-Q416 PolarHBondContact O-N 3.09Å; M413-Q416 PolarHBondContact O-N 3.11Å; L414-Q416 VanDerWaalsContact C-N 3.3Å; L414-Q416 PolarHBondContact O-N 3.15Å; Q416-A419 PolarHBondContact O-N 2.96Å; Q416-R420 WeakPolarHBondContact O-CG 3.48Å; Q416-R420 PolarHBondContact O-N 3.11Å; Q416-R420 VanDerWaalsContact O-N 3.15Å
417V92.8Very high86.7Confident0 Ų053.3 Ų53.30%026%0.26CS..Hα-helixtrans-60.6-50.6171168.70000110.2F393 E396 L397 A400 M413 L414 A419 R420 I421F393-V417 HydrophobicContact CD2-CG1 3.82Å; F393-V417 HydrophobicContact CE2-CG1 4.05Å; E396-V417 HydrophobicContact CB-CB 4.47Å; E396-V417 HydrophobicContact CB-CG1 4.02Å; E396-V417 HydrophobicContact CB-CG2 4.29Å; L397-V417 HydrophobicContact CB-CG2 4.48Å; A400-V417 HydrophobicContact CB-CG2 3.8Å; M413-V417 WeakPolarHBondContact O-CG2 3.32Å; M413-V417 PolarHBondContact O-N 3.03Å; L414-V417 WeakPolarHBondContact O-CB 3.26Å; L414-V417 PolarHBondContact O-N 3.39Å; V417-A419 VanDerWaalsContact C-N 3.31Å; V417-A419 PolarHBondContact O-N 3.38Å; V417-R420 PolarHBondContact O-N 2.96Å; V417-I421 HydrophobicContact CG1-CD1 3.53Å; V417-I421 HydrophobicContact CG1-CG1 4.42Å; V417-I421 WeakPolarHBondContact O-CG1 3.33Å; V417-I421 PolarHBondContact O-N 3.38Å
418N90.8Very high85.2Confident26 Ų2652.6 Ų52.614%0.13926%0.261CS..Hα-helixtrans-55.2-45176.1-75.114.9000112L414 V415 R420 I421 K422 M439 S440L414-N418 PolarHBondContact O-N 3.32Å; L414-N418 PolarHBondContact O-OD1 3.43Å; V415-N418 PolarHBondContact O-N 2.92Å; N418-R420 PolarHBondContact O-N 3.32Å; N418-I421 PolarHBondContact O-N 2.99Å; N418-K422 WeakPolarHBondContact O-CB 3.3Å; N418-K422 PolarHBondContact O-N 3.35Å; N418-M439 HydrophobicContact CB-CE 3.81Å; N418-S440 PolarHBondContact ND2-O 3.18Å; N418-S440 VanDerWaalsContact ND2-O 3.14Å; N418-S440 PolarHBondContact OD1-O 2.89Å; N418-S440 PolarHBondContact OD1-OG 3.26Å
419A85.2Confident83.8Confident48 Ų4854.7 Ų54.740%0.39728%0.275SS..Hα-helixtrans-61-44.4179.500000112.8V415 Q416 V417 K422 E423V415-A419 PolarHBondContact O-N 2.87Å; Q416-A419 PolarHBondContact O-N 2.96Å; V417-A419 VanDerWaalsContact C-N 3.31Å; V417-A419 PolarHBondContact O-N 3.38Å; A419-K422 WeakPolarHBondContact O-CB 3.49Å; A419-K422 PolarHBondContact O-N 2.95Å; A419-E423 PolarHBondContact O-N 2.87Å
420R86.9Confident82.1Confident52 Ų5257.2 Ų57.220%0.19631%0.31CS..Hα-helixtrans-74.8-31179.7-65.2177-166.6159.75.3113.2E396 H404 Q416 V417 N418 E423 R424E396-R420 HydrophobicContact CG-CB 4.02Å; E396-R420 WeakPolarHBondContact OE2-CD 3.4Å; E396-R420 IonicContact OE2-CZ 3.02Å; E396-R420 IonicContact OE2-NE 3.89Å; E396-R420 IonicContact OE2-NH1 3.86Å; E396-R420 PolarHBondContact OE2-NH1 3.25Å; E396-R420 VanDerWaalsContact OE2-NH1 3.11Å; H404-R420 PolarHBondContact NE2-NH2 2.79Å; Q416-R420 WeakPolarHBondContact O-CG 3.48Å; Q416-R420 PolarHBondContact O-N 3.11Å; Q416-R420 VanDerWaalsContact O-N 3.15Å; V417-R420 PolarHBondContact O-N 2.96Å; N418-R420 PolarHBondContact O-N 3.32Å; R420-E423 PolarHBondContact O-N 3.2Å; R420-R424 WeakPolarHBondContact O-CG 3.29Å; R420-R424 PolarHBondContact O-N 3.46Å
421I83.1Confident80.8Confident0 Ų060.5 Ų60.50%033%0.33CS..Hα-helixtrans-67.8-40.6174.2-68.4169000110.2F393 E396 V417 N418 E423 R424 E438 S440F393-I421 HydrophobicContact CB-CD1 4.03Å; F393-I421 HydrophobicContact CD2-CD1 4.01Å; E396-I421 HydrophobicContact CB-CD1 4.47Å; E396-I421 HydrophobicContact CB-CG1 4.28Å; E396-I421 HydrophobicContact CG-CG1 3.98Å; V417-I421 HydrophobicContact CG1-CD1 3.53Å; V417-I421 HydrophobicContact CG1-CG1 4.42Å; V417-I421 WeakPolarHBondContact O-CG1 3.33Å; V417-I421 PolarHBondContact O-N 3.38Å; N418-I421 PolarHBondContact O-N 2.99Å; I421-E423 PolarHBondContact O-N 3.09Å; I421-R424 WeakPolarHBondContact O-CB 3.21Å; I421-R424 PolarHBondContact O-N 3.5Å; I421-E438 HydrophobicContact CG2-CB 4.03Å; I421-E438 HydrophobicContact CG2-CG 4.07Å; I421-E438 WeakPolarHBondContact CG2-O 3.45Å; I421-S440 WeakPolarHBondContact CD1-OG 3.34Å
422K82.8Confident79.3Confident139 Ų13963 Ų6360%0.60435%0.352SS*.Hα-helixtrans-55.6-33.4170.5179.7-176.3174.8-175.40112.9N418 A419 K437 M439N418-K422 WeakPolarHBondContact O-CB 3.3Å; N418-K422 PolarHBondContact O-N 3.35Å; A419-K422 WeakPolarHBondContact O-CB 3.49Å; A419-K422 PolarHBondContact O-N 2.95Å; K422-K437 WeakPolarHBondContact O-CE 3.24Å; K422-K437 PolarHBondContact O-NZ 3.3Å; K422-M439 HydrophobicContact CB-SD 4.17Å
423E77.3Confident77.7Confident157 Ų15763 Ų6373%0.73435%0.35SS*.Hα-helixtrans-77.1-21.9177.9-70.4170.9177.200113.7A419 R420 I421A419-E423 PolarHBondContact O-N 2.87Å; R420-E423 PolarHBondContact O-N 3.2Å; I421-E423 PolarHBondContact O-N 3.09Å
424R75.4Confident76.2Confident46 Ų4666.4 Ų66.417%0.17437%0.365CS..  trans-74.8151.1179.3-71.2169169.2-119.11.4112.7W392 E396 R420 I421 K437W392-R424 HydrophobicContact CD2-CB 4.12Å; W392-R424 HydrophobicContact CE3-CB 3.65Å; W392-R424 HydrophobicContact CE3-CG 4.44Å; W392-R424 VanDerWaalsContact CG-NH1 3.29Å; W392-R424 HydrophobicContact CH2-CB 3.97Å; W392-R424 HydrophobicContact CZ2-CB 4.39Å; W392-R424 HydrophobicContact CZ3-CB 3.57Å; E396-R424 IonicContact OE1-CZ 2.67Å; E396-R424 VanDerWaalsContact OE1-CZ 3.23Å; E396-R424 IonicContact OE1-NE 3.27Å; E396-R424 PolarHBondContact OE1-NE 2.75Å; E396-R424 IonicContact OE1-NH2 3.27Å; E396-R424 PolarHBondContact OE1-NH2 3.15Å; R420-R424 WeakPolarHBondContact O-CG 3.29Å; R420-R424 PolarHBondContact O-N 3.46Å; I421-R424 WeakPolarHBondContact O-CB 3.21Å; I421-R424 PolarHBondContact O-N 3.5Å; R424-K437 WeakPolarHBondContact O-CE 3.24Å; R424-K437 PolarHBondContact O-NZ 3.11Å
425E70.4Confident74.9Confident88 Ų8873.4 Ų73.441%0.41139%0.392SS..  trans-141143.6-179.2-176.3173.1174.700110.9Y427 R435E425-Y427 PolarHBondContact O-N 3.45Å; E425-R435 HydrophobicContact CG-CB 4.46Å; E425-R435 WeakPolarHBondContact OE1-CB 3.35Å; E425-R435 WeakPolarHBondContact OE1-CG 3.28Å; E425-R435 IonicContact OE1-CZ 2.72Å; E425-R435 IonicContact OE1-NE 2.98Å; E425-R435 PolarHBondContact OE1-NE 3.17Å; E425-R435 IonicContact OE1-NH2 3.96Å; E425-R435 PolarHBondContact OE1-NH2 3.03Å
426G63.7Low73.6Confident4 Ų470 Ų704%0.04137%0.371CS..  trans-68.3110.7-17500000113.7A428 H433 H434 R435 C436G426-A428 PolarHBondContact O-N 2.98Å; G426-H433 CarbonylContact C-O 3.52Å; G426-H433 WeakPolarHBondContact CA-O 3.31Å; G426-H434 CarbonylContact O-C 3.42Å; G426-H434 WeakPolarHBondContact O-CA 3.4Å; G426-H434 PolarHBondContact O-ND1 2.82Å; G426-R435 PolarHBondContact O-N 2.88Å; G426-C436 PolarHBondContact N-O 3.08Å
427Y68.1Low72.8Confident201 Ų20169.4 Ų69.479%0.78837%0.368SS*.  trans-99.682.3174.3-160.8-92.9000112.2E425 P429E425-Y427 PolarHBondContact O-N 3.45Å; Y427-P429 HydrophobicContact CD1-CG 4.43Å; Y427-P429 HydrophobicContact CE1-CG 3.91Å; Y427-P429 HydrophobicContact CE2-CG 4.08Å
428A62.5Low72Confident34 Ų3469.6 Ų69.628%0.28137%0.369SS..  trans-140.566.517200000111.7G426 T431 H433 H434G426-A428 PolarHBondContact O-N 2.98Å; A428-T431 WeakPolarHBondContact CB-OG1 3.48Å; A428-T431 PolarHBondContact O-N 3.12Å; A428-T431 VanDerWaalsContact O-N 3.16Å; A428-T431 PolarHBondContact O-OG1 3.42Å; A428-H433 HydrophobicContact CB-CB 4.12Å; A428-H434 WeakPolarHBondContact O-CB 3Å
429P64.4Low71.8Confident70 Ų7071 Ų7146%0.45538%0.375SS..THydrogen-bonded Turntrans-50.4138.1-173.8-27.435.3000114.1Y427 T431Y427-P429 HydrophobicContact CD1-CG 4.43Å; Y427-P429 HydrophobicContact CE1-CG 3.91Å; Y427-P429 HydrophobicContact CE2-CG 4.08Å; P429-T431 VanDerWaalsContact C-N 3.32Å
430G58.3Low71.9Confident87 Ų8768.7 Ų68.790%0.89736%0.356SS*.THydrogen-bonded Turntrans80.74.8-176.600000115.2
431T69.4Low72Confident70 Ų7068.4 Ų68.443%0.42936%0.357SS..SBendtrans-121.9163174.776.20000111.6A428 P429 H433 H434A428-T431 WeakPolarHBondContact CB-OG1 3.48Å; A428-T431 PolarHBondContact O-N 3.12Å; A428-T431 VanDerWaalsContact O-N 3.16Å; A428-T431 PolarHBondContact O-OG1 3.42Å; P429-T431 VanDerWaalsContact C-N 3.32Å; T431-H433 PolarHBondContact O-N 3.04Å; T431-H433 VanDerWaalsContact O-N 3.13Å; T431-H433 PolarHBondContact OG1-N 3.17Å; T431-H434 WeakPolarHBondContact O-CB 3.04Å; T431-H434 PolarHBondContact O-N 3.22Å
432A62.2Low72.5Confident79 Ų7971 Ų7165%0.65337%0.369SS*.THydrogen-bonded Turntrans-61.6-14.8171.700000113.7M319 H434M319-A432 HydrophobicContact SD-CB 4.45Å; A432-H434 VanDerWaalsContact C-N 3.31Å
433H63.2Low72.9Confident82 Ų8267.9 Ų67.938%0.3836%0.361SS..THydrogen-bonded Turntrans-896.6174.9-48.1-67.6000113M384 G426 A428 T431 C436M384-H433 HydrophobicContact CE-CB 4.31Å; G426-H433 CarbonylContact C-O 3.52Å; G426-H433 WeakPolarHBondContact CA-O 3.31Å; A428-H433 HydrophobicContact CB-CB 4.12Å; T431-H433 PolarHBondContact O-N 3.04Å; T431-H433 VanDerWaalsContact O-N 3.13Å; T431-H433 PolarHBondContact OG1-N 3.17Å; H433-C436 PolarHBondContact O-SG 2.9Å
434H64.3Low73.6Confident73 Ų7363.4 Ų63.434%0.33835%0.347SS..SBendtrans-79.8135.7167.3-161.523.2000110.4G426 A428 T431 A432 C436G426-H434 CarbonylContact O-C 3.42Å; G426-H434 WeakPolarHBondContact O-CA 3.4Å; G426-H434 PolarHBondContact O-ND1 2.82Å; A428-H434 WeakPolarHBondContact O-CB 3Å; T431-H434 WeakPolarHBondContact O-CB 3.04Å; T431-H434 PolarHBondContact O-N 3.22Å; A432-H434 VanDerWaalsContact C-N 3.31Å; H434-C436 PolarHBondContact O-N 2.94Å
435R66.3Low74.3Confident148 Ų14863.3 Ų63.356%0.55835%0.354SS*.SBendtrans63-1.1178.5-51.2-159.266.6-144.3-12.4116.1E425 G426E425-R435 HydrophobicContact CG-CB 4.46Å; E425-R435 WeakPolarHBondContact OE1-CB 3.35Å; E425-R435 WeakPolarHBondContact OE1-CG 3.28Å; E425-R435 IonicContact OE1-CZ 2.72Å; E425-R435 IonicContact OE1-NE 2.98Å; E425-R435 PolarHBondContact OE1-NE 3.17Å; E425-R435 IonicContact OE1-NH2 3.96Å; E425-R435 PolarHBondContact OE1-NH2 3.03Å; G426-R435 PolarHBondContact O-N 2.88Å
436C66.8Low75.3Confident6 Ų660.5 Ų60.54%0.04134%0.341CS..  trans-59.6153.5172.670.40000112M384 G426 H433 H434M384-C436 VanDerWaalsContact CE-SG 3.6Å; G426-C436 PolarHBondContact N-O 3.08Å; H433-C436 PolarHBondContact O-SG 2.9Å; H434-C436 PolarHBondContact O-N 2.94Å
437K74.9Confident76.4Confident48 Ų4864.9 Ų64.921%0.20937%0.37CS..BIsolated β-bridgetrans-107.2168.8177.5-56.8-61.1-67179.70110D320 K422 R424D320-K437 HydrophobicContact CB-CB 4.2Å; D320-K437 PolarHBondContact O-N 2.65Å; K422-K437 WeakPolarHBondContact O-CE 3.24Å; K422-K437 PolarHBondContact O-NZ 3.3Å; R424-K437 WeakPolarHBondContact O-CE 3.24Å; R424-K437 PolarHBondContact O-NZ 3.11Å
438E76.6Confident77.5Confident4 Ų460.3 Ų60.32%0.01935%0.354CS..  trans-136.7152.7164.4-179.2176.3-139.200106.2A383 M384 W392 I421A383-E438 WeakPolarHBondContact CA-OE1 3.42Å; M384-E438 HydrophobicContact CB-CB 4.2Å; M384-E438 HydrophobicContact CB-CG 4.45Å; M384-E438 HydrophobicContact CG-CB 4.07Å; M384-E438 PolarHBondContact N-OE1 3.25Å; W392-E438 WeakPolarHBondContact CB-OE2 3.04Å; W392-E438 HydrophobicContact CE3-CB 3.85Å; W392-E438 HydrophobicContact CZ3-CB 3.92Å; I421-E438 HydrophobicContact CG2-CB 4.03Å; I421-E438 HydrophobicContact CG2-CG 4.07Å; I421-E438 WeakPolarHBondContact CG2-O 3.45Å
439M85.6Confident79Confident54 Ų5461.9 Ų61.927%0.26636%0.358SS..  trans-142128.5168.4-172.664.7-173.900109.1S377 L378 N418 K422S377-M439 CarbonylContact C-O 3.58Å; S377-M439 WeakPolarHBondContact CA-O 3.48Å; L378-M439 HydrophobicContact CD1-CB 4.15Å; L378-M439 HydrophobicContact CD1-CG 4.37Å; L378-M439 HydrophobicContact CD2-CB 4.26Å; L378-M439 HydrophobicContact CD2-CG 4.05Å; L378-M439 HydrophobicContact CG-CB 4.08Å; L378-M439 HydrophobicContact CG-CG 4.37Å; L378-M439 WeakPolarHBondContact CG-O 3.48Å; L378-M439 PolarHBondContact N-O 3.24Å; L378-M439 VanDerWaalsContact N-O 3.13Å; N418-M439 HydrophobicContact CB-CE 3.81Å; K422-M439 HydrophobicContact CB-SD 4.17Å
440S88.5Confident80.5Confident1 Ų158.6 Ų58.61%0.00734%0.337CS..  trans-89.2149.9174.150.70000111.5F375 A376 N418 I421F375-S440 WeakPolarHBondContact O-CA 3.15Å; F375-S440 WeakPolarHBondContact O-CB 3.41Å; A376-S440 WeakPolarHBondContact O-CA 3.32Å; N418-S440 PolarHBondContact ND2-O 3.18Å; N418-S440 VanDerWaalsContact ND2-O 3.14Å; N418-S440 PolarHBondContact OD1-O 2.89Å; N418-S440 PolarHBondContact OD1-OG 3.26Å; I421-S440 WeakPolarHBondContact CD1-OG 3.34Å
441E88.9Confident82.3Confident46 Ų4655.5 Ų55.522%0.21530%0.298CS..EExtended strand (participates in β ladder)trans-120.6158168.361.2174.9-129.900110.1R315 F375 L378 K379R315-E441 IonicContact CZ-OE1 3.41Å; R315-E441 VanDerWaalsContact CZ-OE1 3.23Å; R315-E441 IonicContact NH1-OE1 3.19Å; R315-E441 PolarHBondContact NH1-OE1 2.88Å; R315-E441 IonicContact NH1-OE2 2.66Å; R315-E441 IonicContact NH2-OE1 2.69Å; R315-E441 PolarHBondContact NH2-OE1 2.78Å; F375-E441 HydrophobicContact CB-CG 4.15Å; F375-E441 HydrophobicContact CD2-CG 4.18Å; F375-E441 PolarHBondContact N-O 3.49Å; F375-E441 PolarHBondContact O-N 2.96Å; L378-E441 HydrophobicContact CD2-CB 3.8Å; L378-E441 HydrophobicContact CD2-CG 4.19Å; K379-E441 PolarHBondContact N-OE2 2.98Å
442F92.3Very high83.5Confident55 Ų5552.3 Ų52.324%0.24128%0.278CS..EExtended strand (participates in β ladder)trans-135.814916672.4-88.2000110.9I372 C373 L414 V415I372-F442 HydrophobicContact CD1-CD2 4.33Å; I372-F442 HydrophobicContact CG1-CD2 4.45Å; C373-F442 CarbonylContact O-C 3.58Å; C373-F442 WeakPolarHBondContact O-CA 3.38Å; C373-F442 WeakPolarHBondContact O-CB 3.46Å; L414-F442 HydrophobicContact CB-CB 4.47Å; L414-F442 HydrophobicContact CB-CD1 3.58Å; L414-F442 HydrophobicContact CB-CD2 4.46Å; L414-F442 HydrophobicContact CB-CE1 3.82Å; L414-F442 HydrophobicContact CB-CG 3.94Å; L414-F442 HydrophobicContact CB-CZ 4.36Å; L414-F442 HydrophobicContact CD1-CB 3.85Å; L414-F442 HydrophobicContact CD1-CD1 4.39Å; L414-F442 HydrophobicContact CD1-CD2 4.06Å; L414-F442 HydrophobicContact CD1-CG 3.86Å; V415-F442 HydrophobicContact CG2-CE1 3.84Å; V415-F442 HydrophobicContact CG2-CZ 3.93Å
443T91.5Very high85Confident73 Ų7348.6 Ų48.645%0.44825%0.247SC..EExtended strand (participates in β ladder)trans-116.6145.5172.559.80000109.5I372 C373 F375I372-T443 WeakPolarHBondContact CA-O 3.21Å; C373-T443 PolarHBondContact N-O 3.38Å; C373-T443 PolarHBondContact O-N 2.95Å; F375-T443 HydrophobicContact CE2-CG2 4.44Å
444S92.2Very high86.3Confident63 Ų6344.7 Ų44.744%0.44123%0.229SC..EExtended strand (participates in β ladder)trans-135.4135.9-178-174.80000111.2L446S444-L446 WeakPolarHBondContact OG-CG 3.16Å; S444-L446 PolarHBondContact OG-N 3.23Å
445S90.1Very high87Confident44 Ų4446.5 Ų46.531%0.30824%0.236SC..  trans-123.522.3167.662.70000110.5D370 M371D370-S445 PolarHBondContact N-O 3.22Å; M371-S445 WeakPolarHBondContact CA-OG 3.01Å; M371-S445 WeakPolarHBondContact CB-OG 3.44Å; M371-S445 PolarHBondContact N-OG 3.33Å; M371-S445 PolarHBondContact O-N 3.31Å; M371-S445 PolarHBondContact O-OG 3.09Å
446L91.1Very high87.4Confident29 Ų2941.7 Ų41.715%0.15222%0.218CC..  trans-67.7131.2176.6-60.8179.5000110.1Y184 P306 I372 S444 L450Y184-L446 HydrophobicContact CE2-CB 4.09Å; Y184-L446 HydrophobicContact CE2-CD1 4.5Å; Y184-L446 HydrophobicContact CE2-CD2 3.8Å; Y184-L446 HydrophobicContact CE2-CG 4.34Å; Y184-L446 VanDerWaalsContact OH-CA 3.25Å; Y184-L446 WeakPolarHBondContact OH-CA 3.29Å; P306-L446 HydrophobicContact CB-CD2 4.47Å; I372-L446 HydrophobicContact CB-CD1 4.01Å; I372-L446 HydrophobicContact CB-CD2 4.21Å; I372-L446 HydrophobicContact CB-CG 4Å; I372-L446 HydrophobicContact CD1-CD1 3.84Å; I372-L446 HydrophobicContact CG1-CD1 4.49Å; I372-L446 HydrophobicContact CG2-CD1 4.13Å; I372-L446 HydrophobicContact CG2-CD2 4.21Å; I372-L446 HydrophobicContact CG2-CG 4.38Å; S444-L446 WeakPolarHBondContact OG-CG 3.16Å; S444-L446 PolarHBondContact OG-N 3.23Å; L446-L450 HydrophobicContact CD1-CB 3.94Å; L446-L450 HydrophobicContact CD1-CD2 4.08Å; L446-L450 HydrophobicContact CD2-CD2 4.37Å
447C88.3Confident87.5Confident96 Ų9648.1 Ų48.165%0.64925%0.248SC*.SBendtrans-92.84.3176.6-57.20000113.5Y184Y184-C447 PolarHBondContact OH-N 3.23Å
448K90.4Very high86.8Confident105 Ų10547.2 Ų47.246%0.45725%0.247SC..SBendtrans-156.9165.7-178.5-62.7-170.7172.7-162.80111S183 Y184S183-K448 WeakPolarHBondContact O-CD 3.44Å; S183-K448 PolarHBondContact O-NZ 3.38Å; Y184-K448 HydrophobicContact CD1-CD 4.48Å; Y184-K448 HydrophobicContact CD2-CB 3.95Å; Y184-K448 HydrophobicContact CE1-CB 4.45Å; Y184-K448 HydrophobicContact CE2-CB 3.85Å; Y184-K448 WeakPolarHBondContact CE2-O 3.22Å; Y184-K448 HydrophobicContact CG-CB 4.3Å
449D94.3Very high85.8Confident67 Ų6756.4 Ų56.436%0.35829%0.29SS..  trans-66.5143.3170.7-52.7-41.7000111.9S183 Y184 H409 Y451S183-D449 CarbonylContact C-O 3.58Å; S183-D449 VanDerWaalsContact CA-O 3.24Å; S183-D449 WeakPolarHBondContact CA-O 3.5Å; S183-D449 VanDerWaalsContact CB-O 3.24Å; S183-D449 WeakPolarHBondContact CB-O 3.4Å; Y184-D449 WeakPolarHBondContact CD2-O 3.44Å; Y184-D449 PolarHBondContact N-O 3.22Å; H409-D449 HydrophobicContact CB-CB 4.29Å; H409-D449 IonicContact CD2-OD1 3.96Å; D449-Y451 HydrophobicContact CB-CD2 4.17Å; D449-Y451 HydrophobicContact CB-CE2 3.64Å
450L96.1Very high84Confident1 Ų166.4 Ų66.41%0.00533%0.326CS..  trans-118.992.7-177.9179.353000110.8Y184 M186 P306 M308 I372 H409 L410 L446 L452Y184-L450 HydrophobicContact CD2-CB 4.04Å; Y184-L450 HydrophobicContact CD2-CD1 4.12Å; Y184-L450 HydrophobicContact CE2-CB 4.38Å; M186-L450 HydrophobicContact CG-CD1 4.17Å; M186-L450 HydrophobicContact SD-CD1 4.15Å; P306-L450 HydrophobicContact CB-CD1 3.68Å; P306-L450 HydrophobicContact CB-CD2 3.63Å; P306-L450 HydrophobicContact CB-CG 4.27Å; P306-L450 HydrophobicContact CG-CD1 3.64Å; P306-L450 HydrophobicContact CG-CD2 4.49Å; M308-L450 HydrophobicContact CG-CD2 3.92Å; M308-L450 HydrophobicContact SD-CD2 3.92Å; I372-L450 HydrophobicContact CG2-CD2 4.3Å; H409-L450 CarbonylContact C-O 3.59Å; H409-L450 VanDerWaalsContact CA-O 3.31Å; H409-L450 WeakPolarHBondContact CA-O 3.32Å; L410-L450 HydrophobicContact CB-CB 4.37Å; L410-L450 HydrophobicContact CB-CD2 4.27Å; L410-L450 HydrophobicContact CB-CG 4.26Å; L410-L450 HydrophobicContact CD2-CD2 3.92Å; L410-L450 PolarHBondContact N-O 3.29Å; L446-L450 HydrophobicContact CD1-CB 3.94Å; L446-L450 HydrophobicContact CD1-CD2 4.08Å; L446-L450 HydrophobicContact CD2-CD2 4.37Å; L450-L452 HydrophobicContact CD1-CD2 4.4Å; L450-L452 HydrophobicContact CG-CD2 4.5Å
451Y95.8Very high83.8Confident22 Ų2269.7 Ų69.79%0.08634%0.342CS..  trans-95.6142.7169.6-60.5-84000109.9F175 H179 M186 H409 D449 F453F175-Y451 AromaticContact CE1-CD1 3.72Å; F175-Y451 HydrophobicContact CE1-CD1 3.72Å; F175-Y451 AromaticContact CE1-CE1 3.86Å; F175-Y451 HydrophobicContact CE1-CE1 3.86Å; F175-Y451 HydrophobicContact CE1-CG 4.3Å; F175-Y451 AromaticContact CZ-CD1 3.87Å; F175-Y451 HydrophobicContact CZ-CD1 3.87Å; F175-Y451 AromaticContact CZ-CE1 3.51Å; F175-Y451 HydrophobicContact CZ-CE1 3.51Å; H179-Y451 HydrophobicContact CB-CD2 4.2Å; H179-Y451 HydrophobicContact CB-CE2 3.95Å; H179-Y451 AromaticContact CD2-CE2 3.98Å; H179-Y451 AromaticContact CD2-CZ 3.74Å; H179-Y451 PolarHBondContact CD2-OH 2.88Å; M186-Y451 WeakPolarHBondContact CG-O 3.48Å; H409-Y451 HydrophobicContact CB-CD1 3.94Å; H409-Y451 HydrophobicContact CB-CD2 4.37Å; H409-Y451 HydrophobicContact CB-CE1 3.7Å; H409-Y451 HydrophobicContact CB-CE2 4.15Å; H409-Y451 HydrophobicContact CB-CG 4.27Å; H409-Y451 VanDerWaalsContact N-CE1 3.31Å; D449-Y451 HydrophobicContact CB-CD2 4.17Å; D449-Y451 HydrophobicContact CB-CE2 3.64Å; Y451-F453 VanDerWaalsContact CB-CE1 3.47Å; Y451-F453 HydrophobicContact CD2-CE1 4.44Å; Y451-F453 HydrophobicContact CD2-CZ 4.15Å; Y451-F453 HydrophobicContact CG-CE1 4.01Å; Y451-F453 HydrophobicContact CG-CZ 4.09Å
452L94.1Very high83.5Confident2 Ų270.9 Ų70.91%0.0135%0.349CS..  trans-95.1-8-175.3-58.2179.3000113.7M186 R191 L230 M308 L401 A405 M413 L450M186-L452 HydrophobicContact CE-CD2 4.09Å; R191-L452 VanDerWaalsContact CZ-O 3.28Å; R191-L452 PolarHBondContact NE-O 3.03Å; R191-L452 PolarHBondContact NH2-O 3.08Å; L230-L452 HydrophobicContact CD1-CD1 4.09Å; L230-L452 HydrophobicContact CD2-CB 4.16Å; L230-L452 HydrophobicContact CD2-CD1 4.25Å; M308-L452 HydrophobicContact CE-CD2 4.49Å; M308-L452 HydrophobicContact SD-CD2 4.1Å; L401-L452 HydrophobicContact CD2-CD1 3.57Å; A405-L452 HydrophobicContact CB-CB 4.27Å; A405-L452 HydrophobicContact CB-CD1 4.14Å; M413-L452 HydrophobicContact CE-CD1 4.23Å; L450-L452 HydrophobicContact CD1-CD2 4.4Å; L450-L452 HydrophobicContact CG-CD2 4.5Å
453F93.2Very high83Confident1 Ų171.8 Ų71.80%0.00436%0.355CS..  trans39.456.1176.5-56.1-51000115.2C171 F175 Y176 H179 C180 M186 Y451 K455 Y456C171-F453 HydrophobicContact CB-CB 4.48Å; F175-F453 HydrophobicContact CD1-CE1 4.16Å; F175-F453 HydrophobicContact CE1-CE1 4.06Å; Y176-F453 HydrophobicContact CD2-CB 4.15Å; Y176-F453 AromaticContact CD2-CD1 3.87Å; Y176-F453 HydrophobicContact CD2-CD1 3.87Å; Y176-F453 AromaticContact CD2-CD2 3.65Å; Y176-F453 HydrophobicContact CD2-CD2 3.65Å; Y176-F453 HydrophobicContact CD2-CE1 4.1Å; Y176-F453 AromaticContact CD2-CE2 3.9Å; Y176-F453 HydrophobicContact CD2-CE2 3.9Å; Y176-F453 AromaticContact CD2-CG 3.64Å; Y176-F453 HydrophobicContact CD2-CG 3.64Å; Y176-F453 HydrophobicContact CD2-CZ 4.11Å; Y176-F453 AromaticContact CE2-CD2 3.78Å; Y176-F453 HydrophobicContact CE2-CD2 3.78Å; Y176-F453 HydrophobicContact CE2-CE2 4.01Å; Y176-F453 HydrophobicContact CE2-CG 4.2Å; H179-F453 HydrophobicContact CB-CE1 4.48Å; H179-F453 HydrophobicContact CB-CZ 4.32Å; C180-F453 HydrophobicContact CB-CE2 4.21Å; C180-F453 HydrophobicContact CB-CZ 4.22Å; M186-F453 HydrophobicContact CB-CD2 4.01Å; Y451-F453 VanDerWaalsContact CB-CE1 3.47Å; Y451-F453 HydrophobicContact CD2-CE1 4.44Å; Y451-F453 HydrophobicContact CD2-CZ 4.15Å; Y451-F453 HydrophobicContact CG-CE1 4.01Å; Y451-F453 HydrophobicContact CG-CZ 4.09Å; F453-K455 PolarHBondContact O-N 3.18Å; F453-Y456 PolarHBondContact O-N 2.7Å
454P90.3Very high82.5Confident0 Ų071.7 Ų71.70%035%0.349CS..THydrogen-bonded Turntrans-51.8130.3-178.319.6-32.7000114V168 L169 P170 C171 L230 A405 R406 Y456V168-P454 HydrophobicContact CG1-CB 3.71Å; V168-P454 HydrophobicContact CG1-CG 4.21Å; L169-P454 WeakPolarHBondContact O-CB 3.48Å; L169-P454 WeakPolarHBondContact O-CG 3.49Å; P170-P454 CarbonylContact C-O 3.51Å; P170-P454 WeakPolarHBondContact CA-O 3.47Å; C171-P454 HydrophobicContact CB-CG 4.39Å; C171-P454 PolarHBondContact N-O 3.11Å; L230-P454 HydrophobicContact CD2-CB 4.18Å; A405-P454 HydrophobicContact CB-CG 4.39Å; A405-P454 WeakPolarHBondContact O-CD 3.21Å; R406-P454 HydrophobicContact CB-CG 3.89Å; P454-Y456 PolarHBondContact O-N 3.38Å
455K79.4Confident81.9Confident111 Ų11172.3 Ų72.348%0.48334%0.344SS..THydrogen-bonded Turntrans60.211.1170.3-58.8167.9-179.7170.70114.7V168 P170 F453V168-K455 WeakPolarHBondContact O-CE 3.49Å; V168-K455 PolarHBondContact O-NZ 2.91Å; P170-K455 HydrophobicContact CB-CB 4.11Å; P170-K455 HydrophobicContact CB-CD 4.45Å; F453-K455 PolarHBondContact O-N 3.18Å
456Y76Confident81.4Confident48 Ų4874.1 Ų74.119%0.18835%0.346CS..  trans-88.3119.5170.2-178.1-90.3000109.7P173 Y176 F453 P454 P458P173-Y456 HydrophobicContact CB-CE2 4.09Å; P173-Y456 HydrophobicContact CG-CE2 4.42Å; Y176-Y456 HydrophobicContact CD1-CD1 4Å; Y176-Y456 AromaticContact CD1-CE1 3.26Å; Y176-Y456 HydrophobicContact CD1-CE1 3.26Å; Y176-Y456 HydrophobicContact CD1-CE2 4.22Å; Y176-Y456 AromaticContact CD1-CZ 3.38Å; Y176-Y456 WeakPolarHBondContact CD1-OH 3.3Å; Y176-Y456 AromaticContact CD2-CD1 3.63Å; Y176-Y456 HydrophobicContact CD2-CD1 3.63Å; Y176-Y456 AromaticContact CD2-CE1 3.74Å; Y176-Y456 HydrophobicContact CD2-CE1 3.74Å; Y176-Y456 HydrophobicContact CD2-CG 4.3Å; Y176-Y456 HydrophobicContact CE1-CD1 4.23Å; Y176-Y456 AromaticContact CE1-CE1 3.36Å; Y176-Y456 HydrophobicContact CE1-CE1 3.36Å; Y176-Y456 AromaticContact CE1-CZ 3.82Å; Y176-Y456 AromaticContact CE2-CD1 3.87Å; Y176-Y456 HydrophobicContact CE2-CD1 3.87Å; Y176-Y456 AromaticContact CE2-CE1 3.83Å; Y176-Y456 HydrophobicContact CE2-CE1 3.83Å; Y176-Y456 AromaticContact CG-CD1 3.7Å; Y176-Y456 HydrophobicContact CG-CD1 3.7Å; Y176-Y456 HydrophobicContact CG-CD2 4.47Å; Y176-Y456 AromaticContact CG-CE1 3.46Å; Y176-Y456 HydrophobicContact CG-CE1 3.46Å; Y176-Y456 VanDerWaalsContact CG-CE1 3.46Å; Y176-Y456 HydrophobicContact CG-CE2 4.28Å; Y176-Y456 HydrophobicContact CG-CG 4.2Å; Y176-Y456 AromaticContact CG-CZ 3.78Å; Y176-Y456 AromaticContact CZ-CE1 3.65Å; F453-Y456 PolarHBondContact O-N 2.7Å; P454-Y456 PolarHBondContact O-N 3.38Å; Y456-P458 HydrophobicContact CE1-CB 3.81Å; Y456-P458 HydrophobicContact CE1-CG 4.27Å
457Q67.8Low80.7Confident140 Ų14077.4 Ų77.465%0.65436%0.36SS*.  trans-114.1117.8167.3-72.2-178.5-20.500107.7Q459Q457-Q459 PolarHBondContact O-N 3.13Å
458P60.3Low80.1Confident29 Ų2975.9 Ų75.919%0.18834%0.338CS..  trans-65.7118.9175.924.9-31000109.5N187 Y456 Y460N187-P458 HydrophobicContact CB-CG 4.39Å; Y456-P458 HydrophobicContact CE1-CB 3.81Å; Y456-P458 HydrophobicContact CE1-CG 4.27Å; P458-Y460 HydrophobicContact CB-CD2 4.01Å; P458-Y460 HydrophobicContact CB-CE2 3.71Å; P458-Y460 HydrophobicContact CG-CD2 4.11Å; P458-Y460 HydrophobicContact CG-CE2 3.71Å; P458-Y460 PolarHBondContact O-N 3.24Å
459Q56.3Low79.2Confident198 Ų19873.5 Ų73.593%0.92533%0.328SS*.  trans-71119.5169.7-63.7176.83.800108Q457Q457-Q459 PolarHBondContact O-N 3.13Å
460Y47.4Very low77.9Confident263 Ų26374.1 Ų74.1100%1.03133%0.325SS*.  trans-118.10179-84.6-73.2000109.9P458P458-Y460 HydrophobicContact CB-CD2 4.01Å; P458-Y460 HydrophobicContact CB-CE2 3.71Å; P458-Y460 HydrophobicContact CG-CD2 4.11Å; P458-Y460 HydrophobicContact CG-CE2 3.71Å; P458-Y460 PolarHBondContact O-N 3.24Å

Retrieved 460 of 460 residues in 764.8 ms (Link to these results)