A0A3B3V2F1_9TELE Loading...

Ribonucleoside-diphosphate reductase subunit M2

AlphaFold DB , UniProt , Accession A0A3B3V2F1, Species 9TELE (Poecilia latipinna, sailfin molly), Gene n/a, Length 393 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	37.4	Very low	30.5	Very low	254 Å²	254	158 Å²	158	100%	1.251	83%	0.831	S	S	*	*				0	138	0	-94.9	172.2	159.7	0	0	108.4
2	S	30.8	Very low	30.5	Very low	125 Å²	125	152 Å²	152	87%	0.874	82%	0.821	S	S	*	*			trans	-61.8	151.3	-152.8	-65.6	0	0	0	0	119.5
3	F	27.5	Very low	30.4	Very low	197 Å²	197	159.7 Å²	159.7	86%	0.864	83%	0.831	S	S	*	*			trans	-50.6	160.2	149.9	-88.1	-114.1	0	0	0	113.2
4	I	34.7	Very low	30.2	Very low	138 Å²	138	156.6 Å²	156.6	71%	0.708	83%	0.829	S	S	*	*				152.2	126.3	118	-78.2	-169.4	0	0	0	114.8
5	K	31.9	Very low	31.1	Very low	198 Å²	198	154.3 Å²	154.3	86%	0.861	83%	0.827	S	S	*	*			trans	77.7	130.3	143.5	-83.5	167.9	-173.7	176.9	0	125
6	A	31.2	Very low	30.9	Very low	80 Å²	80	155.8 Å²	155.8	66%	0.661	83%	0.834	S	S	*	*			trans	-87.5	167.1	165.1	0	0	0	0	0	114.1
7	L	27.5	Very low	30.8	Very low	140 Å²	140	153 Å²	153	73%	0.733	83%	0.829	S	S	*	*			trans	94	123.9	134.7	-116.1	83.4	0	0	0	122.4
8	K	29.4	Very low	31	Very low	172 Å²	172	151.8 Å²	151.8	75%	0.748	83%	0.827	S	S	*	*			trans	83.5	124.8	134.3	-92.4	179.5	-165.7	173.5	0	122.1
9	M	28.7	Very low	30.9	Very low	158 Å²	158	154.1 Å²	154.1	78%	0.778	83%	0.829	S	S	*	*				160.9	115.2	107.5	-86.9	-147.6	170.5	0	0	111.2
10	L	27.5	Very low	30.9	Very low	155 Å²	155	153.8 Å²	153.8	81%	0.812	83%	0.826	S	S	*	*				75.5	117.1	98.8	-82.1	161.4	0	0	0	116.5
11	S	28.9	Very low	31	Very low	121 Å²	121	155.4 Å²	155.4	85%	0.846	83%	0.829	S	S	*	*				163.8	134.7	119.1	-177.1	0	0	0	0	112.8
12	A	30.7	Very low	31.1	Very low	86 Å²	86	152.1 Å²	152.1	71%	0.711	81%	0.81	S	S	*	*			trans	-76.9	158.7	177.4	0	0	0	0	0	114.3
13	R	28.3	Very low	31.3	Very low	252 Å²	252	152.4 Å²	152.4	95%	0.951	81%	0.807	S	S	*	*			trans	-160.2	132.9	143.2	-97.4	-179	-170.2	-166.7	1.2	110.6
14	S	28.7	Very low	31.6	Very low	116 Å²	116	151.9 Å²	151.9	81%	0.811	81%	0.813	S	S	*	*			trans	-110.2	-166.9	166.5	-51.1	0	0	0	0	108.7
15	P	42.6	Very low	31.5	Very low	123 Å²	123	149.1 Å²	149.1	80%	0.799	82%	0.818	S	S	*	*				-119.4	167.4	-77.5	37.2	-20.8	0	0	0	112.9
16	L	28.7	Very low	31.6	Very low	178 Å²	178	144.7 Å²	144.7	93%	0.932	81%	0.812	S	S	*	*			trans	-154	144.2	168.5	-83.9	162.2	0	0	0	106.9
17	S	29	Very low	31.8	Very low	108 Å²	108	150 Å²	150	76%	0.755	82%	0.823	S	S	*	*			cis	-171.5	144.6	-20.9	167.1	0	0	0	0	103.9
18	V	34.8	Very low	32	Very low	132 Å²	132	151.5 Å²	151.5	80%	0.8	83%	0.831	S	S	*	*			trans	-58.4	134.9	173.7	177.2	0	0	0	0	111.6
19	K	29.2	Very low	32.1	Very low	195 Å²	195	150.9 Å²	150.9	85%	0.848	84%	0.836	S	S	*	*			trans	-170	135.8	140.3	-106.7	172.1	-174.2	-175	0	112.5
20	N	29.4	Very low	32.4	Very low	147 Å²	147	151.2 Å²	151.2	79%	0.786	84%	0.84	S	S	*	*			trans	101.9	69.8	166.6	-62.1	3.5	0	0	0	117.7
21	Q	34.6	Very low	32.5	Very low	188 Å²	188	152.3 Å²	152.3	88%	0.879	84%	0.844	S	S	*	*			trans	-65.3	149	134.1	-86.3	171.4	-25	0	0	109.3
22	Q	39.4	Very low	32.7	Very low	185 Å²	185	153 Å²	153	86%	0.864	84%	0.843	S	S	*	*			trans	90.1	76.3	-178	-58.3	-178.8	-24	0	0	116.3
23	T	34.2	Very low	32.8	Very low	131 Å²	131	156.9 Å²	156.9	80%	0.804	85%	0.851	S	S	*	*			trans	177.3	80.2	138.6	27.1	0	0	0	0	110.5
24	L	33.6	Very low	32.9	Very low	187 Å²	187	152.3 Å²	152.3	98%	0.979	85%	0.846	S	S	*	*	S	Bend	trans	-156.6	42.7	166.1	-109.3	143.3	0	0	0	110.3
25	G	32.8	Very low	33.4	Very low	79 Å²	79	156.6 Å²	156.6	81%	0.814	85%	0.849	S	S	*	*	S	Bend	trans	-133.6	23.9	-176.3	0	0	0	0	0	114.3
26	S	34.5	Very low	33	Very low	105 Å²	105	159.2 Å²	159.2	73%	0.734	85%	0.851	S	S	*	*	S	Bend	trans	-147.6	29.4	-173.3	68.1	0	0	0	0	115.9
27	Q	34.6	Very low	33.3	Very low	191 Å²	191	158.5 Å²	158.5	89%	0.893	85%	0.848	S	S	*	*	S	Bend	trans	-138.8	35.3	176.5	-78.3	-167.7	-32.5	0	0	114.8
28	L	33.4	Very low	33.5	Very low	172 Å²	172	159.6 Å²	159.6	90%	0.901	85%	0.851	S	S	*	*	S	Bend	trans	-122.4	4.4	172.4	-88	160.6	0	0	0	115.2
29	D	31.4	Very low	33.2	Very low	159 Å²	159	158.8 Å²	158.8	85%	0.85	85%	0.848	S	S	*	*	S	Bend	trans	-98.4	7.5	-173.7	-82.2	-15.2	0	0	0	116
30	N	34.1	Very low	33.4	Very low	165 Å²	165	155.3 Å²	155.3	88%	0.882	85%	0.845	S	S	*	*			trans	-136	63.4	-178.6	-86.6	-19.9	0	0	0	114
31	M	29.2	Very low	33.8	Very low	179 Å²	179	153.8 Å²	153.8	88%	0.882	85%	0.846	S	S	*	*			trans	-124.4	95.3	158.7	-75.3	-174.6	71.6	0	0	109.9
32	T	33	Very low	33.7	Very low	136 Å²	136	153 Å²	153	83%	0.834	85%	0.847	S	S	*	*	P	Polyproline II helix	trans	-76.7	121.3	164.2	38.8	0	0	0	0	109.1
33	L	33.2	Very low	33.6	Very low	166 Å²	166	150.8 Å²	150.8	87%	0.869	84%	0.841	S	S	*	*	P	Polyproline II helix	trans	-84.9	124.1	170	-82.6	158.8	0	0	0	109.5
34	D	29.6	Very low	33.5	Very low	157 Å²	157	148 Å²	148	84%	0.84	83%	0.827	S	S	*	*	P	Polyproline II helix	trans	-61.4	137.8	178.7	-73.3	-46.7	0	0	0	112.7	E36	D34-E36 PolarHBondContact O-N 3.13Å
35	K	40.4	Very low	33.7	Very low	205 Å²	205	141.6 Å²	141.6	89%	0.891	80%	0.796	S	S	*	*			trans	-84.3	94.9	171.7	-76.5	-179.9	175.4	177.1	0	109.4
36	E	34.2	Very low	34	Very low	178 Å²	178	148.6 Å²	148.6	83%	0.832	80%	0.798	S	S	*	*			trans	-158.4	93.6	161.3	-115.1	171.9	-161.4	0	0	109.1	D34	D34-E36 PolarHBondContact O-N 3.13Å
37	N	34.6	Very low	34.2	Very low	164 Å²	164	146 Å²	146	88%	0.877	78%	0.777	S	S	*	*			trans	150.9	67.3	156.1	-78.2	-32	0	0	0	111.1
38	T	33.4	Very low	34.4	Very low	131 Å²	131	140.3 Å²	140.3	80%	0.804	75%	0.753	S	S	*	*			trans	-123.8	118.9	166.1	-41.2	0	0	0	0	108.1
39	P	29.2	Very low	34.7	Very low	114 Å²	114	135.2 Å²	135.2	74%	0.74	74%	0.736	S	S	*	*			trans	-65.4	137.8	172.5	25.6	-29.8	0	0	0	109.5
40	P	33.3	Very low	35.3	Very low	122 Å²	122	128.9 Å²	128.9	79%	0.792	70%	0.704	S	S	*	*	S	Bend	trans	-81.9	143.1	-175.2	31.2	-31.1	0	0	0	111.9
41	S	37.3	Very low	35.5	Very low	116 Å²	116	127.1 Å²	127.1	81%	0.811	69%	0.688	S	S	*	*			trans	83.7	67	165.9	74.8	0	0	0	0	119.2
42	L	32.8	Very low	36.2	Very low	170 Å²	170	121.5 Å²	121.5	89%	0.89	66%	0.664	S	S	*	*			trans	-137	61.3	150.3	-90.2	166.3	0	0	0	108.1
43	N	36.8	Very low	36.6	Very low	139 Å²	139	115.8 Å²	115.8	74%	0.743	63%	0.63	S	S	*	*			trans	-157.7	78.3	-178.8	-97.6	-28.6	0	0	0	113.5
44	S	32.2	Very low	37	Very low	73 Å²	73	115.8 Å²	115.8	51%	0.51	62%	0.619	S	S	.	*	S	Bend	trans	-149.5	-36.3	154.3	53.3	0	0	0	0	111.5
45	T	38.1	Very low	37.6	Very low	53 Å²	53	115.7 Å²	115.7	33%	0.325	61%	0.611	S	S	.	*	S	Bend	trans	-76	-42.3	-173.2	-26.1	0	0	0	0	113.8	V47 L48 F198	T45-V47 PolarHBondContact O-N 3.16Å; T45-L48 PolarHBondContact O-N 3.03Å; T45-L48 VanDerWaalsContact O-N 3.1Å; T45-F198 HydrophobicContact CG2-CB 4.44Å
46	R	39.2	Very low	38.1	Very low	225 Å²	225	110.4 Å²	110.4	85%	0.849	59%	0.591	S	S	*	*	H	α-helix	trans	-62.7	-18.7	177.9	-142.6	177.5	-175.2	179.1	2.8	113.3
47	V	38.9	Very low	38.6	Very low	51 Å²	51	103.9 Å²	103.9	31%	0.309	56%	0.561	S	S	.	*	H	α-helix	trans	-86.6	-21.9	-179.1	-178.4	0	0	0	0	112	T45 K51	T45-V47 PolarHBondContact O-N 3.16Å; V47-K51 HydrophobicContact CG1-CD 3.93Å; V47-K51 HydrophobicContact CG1-CG 4.24Å; V47-K51 VanDerWaalsContact O-CB 3.31Å; V47-K51 WeakPolarHBondContact O-CB 3.26Å; V47-K51 WeakPolarHBondContact O-CG 3.25Å; V47-K51 PolarHBondContact O-N 3.01Å
48	L	38.1	Very low	39	Very low	71 Å²	71	100 Å²	100	37%	0.372	55%	0.546	S	S	.	.	H	α-helix	trans	-83.5	-42.2	-173.5	-86.4	154.6	0	0	0	113.4	T45 S50 K51 T52	T45-L48 PolarHBondContact O-N 3.03Å; T45-L48 VanDerWaalsContact O-N 3.1Å; L48-S50 VanDerWaalsContact C-N 3.32Å; L48-S50 PolarHBondContact O-N 2.89Å; L48-K51 PolarHBondContact O-N 3.39Å; L48-T52 PolarHBondContact O-N 3.48Å; L48-T52 PolarHBondContact O-OG1 3.18Å
49	A	39.2	Very low	39.4	Very low	66 Å²	66	102.1 Å²	102.1	55%	0.545	55%	0.547	S	S	.	.	H	α-helix	trans	-60.1	-44.8	170.6	0	0	0	0	0	110.6	K51 T52 A53	A49-K51 PolarHBondContact O-N 2.74Å; A49-T52 PolarHBondContact O-N 3.49Å; A49-A53 WeakPolarHBondContact O-CB 3.38Å; A49-A53 PolarHBondContact O-N 3.18Å; A49-A53 VanDerWaalsContact O-N 3.08Å
50	S	45.5	Very low	40.1	Very low	25 Å²	25	98.8 Å²	98.8	18%	0.175	53%	0.529	C	S	.	.	H	α-helix	trans	-70.3	-27.6	178.3	101	0	0	0	0	113.5	L48 R54	L48-S50 VanDerWaalsContact C-N 3.32Å; L48-S50 PolarHBondContact O-N 2.89Å; S50-R54 WeakPolarHBondContact O-CA 3.34Å; S50-R54 WeakPolarHBondContact O-CB 3.34Å; S50-R54 VanDerWaalsContact O-CD 3.29Å; S50-R54 WeakPolarHBondContact O-CD 3.2Å; S50-R54 WeakPolarHBondContact O-CG 3.31Å; S50-R54 PolarHBondContact O-N 2.87Å; S50-R54 VanDerWaalsContact OG-CZ 3.31Å; S50-R54 PolarHBondContact OG-NH1 3.46Å
51	K	38.3	Very low	40.2	Very low	128 Å²	128	96 Å²	96	56%	0.557	52%	0.516	S	S	*	.	H	α-helix	trans	-71.8	-36.1	175.3	-87.2	175.2	179.1	174.2	0	112.9	V47 L48 A49 K55	V47-K51 HydrophobicContact CG1-CD 3.93Å; V47-K51 HydrophobicContact CG1-CG 4.24Å; V47-K51 VanDerWaalsContact O-CB 3.31Å; V47-K51 WeakPolarHBondContact O-CB 3.26Å; V47-K51 WeakPolarHBondContact O-CG 3.25Å; V47-K51 PolarHBondContact O-N 3.01Å; L48-K51 PolarHBondContact O-N 3.39Å; A49-K51 PolarHBondContact O-N 2.74Å; K51-K55 VanDerWaalsContact O-CB 3.27Å; K51-K55 WeakPolarHBondContact O-CB 3.46Å; K51-K55 PolarHBondContact O-N 2.75Å
52	T	41.9	Very low	40.4	Very low	61 Å²	61	96.6 Å²	96.6	37%	0.374	52%	0.517	S	S	.	.	H	α-helix	trans	-73.7	-46.5	178.2	-51.7	0	0	0	0	110.3	L48 A49 K55 I56 Q202	L48-T52 PolarHBondContact O-N 3.48Å; L48-T52 PolarHBondContact O-OG1 3.18Å; A49-T52 PolarHBondContact O-N 3.49Å; T52-K55 PolarHBondContact O-N 2.98Å; T52-I56 HydrophobicContact CG2-CD1 4.32Å; T52-I56 WeakPolarHBondContact O-CG1 3.47Å; T52-I56 PolarHBondContact O-N 3.43Å; T52-Q202 PolarHBondContact OG1-NE2 3.17Å
53	A	42.3	Very low	40.6	Very low	16 Å²	16	95 Å²	95	13%	0.132	51%	0.51	C	S	.	.	H	α-helix	trans	-55	-57.6	169.7	0	0	0	0	0	110.5	A49 K55 I56 F57 E147	A49-A53 WeakPolarHBondContact O-CB 3.38Å; A49-A53 PolarHBondContact O-N 3.18Å; A49-A53 VanDerWaalsContact O-N 3.08Å; A53-K55 VanDerWaalsContact C-N 3.28Å; A53-K55 PolarHBondContact O-N 2.88Å; A53-K55 VanDerWaalsContact O-N 3.17Å; A53-I56 WeakPolarHBondContact O-CB 3.38Å; A53-I56 PolarHBondContact O-N 3.09Å; A53-F57 HydrophobicContact CB-CD2 4.04Å; A53-F57 HydrophobicContact CB-CE2 3.92Å; A53-F57 WeakPolarHBondContact O-CD2 3.28Å; A53-F57 PolarHBondContact O-N 2.98Å; A53-E147 WeakPolarHBondContact CB-OE1 3.47Å
54	R	42.6	Very low	41	Very low	167 Å²	167	93 Å²	93	63%	0.63	51%	0.513	S	S	*	.	H	α-helix	trans	-59.2	-32.4	-179.3	-74.9	168.9	-173.1	169	2.3	114.1	S50 F57 S58	S50-R54 WeakPolarHBondContact O-CA 3.34Å; S50-R54 WeakPolarHBondContact O-CB 3.34Å; S50-R54 VanDerWaalsContact O-CD 3.29Å; S50-R54 WeakPolarHBondContact O-CD 3.2Å; S50-R54 WeakPolarHBondContact O-CG 3.31Å; S50-R54 PolarHBondContact O-N 2.87Å; S50-R54 VanDerWaalsContact OG-CZ 3.31Å; S50-R54 PolarHBondContact OG-NH1 3.46Å; R54-F57 PolarHBondContact O-N 3.29Å; R54-S58 WeakPolarHBondContact O-CA 3.41Å; R54-S58 WeakPolarHBondContact O-CB 3.37Å; R54-S58 PolarHBondContact O-N 3.24Å; R54-S58 PolarHBondContact O-OG 3.32Å
55	K	41.6	Very low	41.8	Very low	154 Å²	154	92.8 Å²	92.8	67%	0.67	51%	0.508	S	S	*	.	H	α-helix	trans	-69.6	-40.3	178.1	-160.4	176.9	-176.4	-173.5	0	110.7	K51 T52 A53 S58	K51-K55 VanDerWaalsContact O-CB 3.27Å; K51-K55 WeakPolarHBondContact O-CB 3.46Å; K51-K55 PolarHBondContact O-N 2.75Å; T52-K55 PolarHBondContact O-N 2.98Å; A53-K55 VanDerWaalsContact C-N 3.28Å; A53-K55 PolarHBondContact O-N 2.88Å; A53-K55 VanDerWaalsContact O-N 3.17Å; K55-S58 PolarHBondContact O-OG 3.45Å
56	I	51	Low	41.9	Very low	94 Å²	94	99.9 Å²	99.9	48%	0.482	53%	0.534	S	S	.	.	H	α-helix	trans	-66.2	-41.9	173.5	-63.6	168	0	0	0	110.7	T52 A53	T52-I56 HydrophobicContact CG2-CD1 4.32Å; T52-I56 WeakPolarHBondContact O-CG1 3.47Å; T52-I56 PolarHBondContact O-N 3.43Å; A53-I56 WeakPolarHBondContact O-CB 3.38Å; A53-I56 PolarHBondContact O-N 3.09Å
57	F	44.1	Very low	42.5	Very low	42 Å²	42	93.4 Å²	93.4	18%	0.184	51%	0.512	C	S	.	.	H	α-helix	trans	-77	-23.1	178	-66.3	-68.6	0	0	0	114.2	A53 R54 E59 A60 E147 I218	A53-F57 HydrophobicContact CB-CD2 4.04Å; A53-F57 HydrophobicContact CB-CE2 3.92Å; A53-F57 WeakPolarHBondContact O-CD2 3.28Å; A53-F57 PolarHBondContact O-N 2.98Å; R54-F57 PolarHBondContact O-N 3.29Å; F57-E59 VanDerWaalsContact C-N 3.33Å; F57-E59 PolarHBondContact O-N 2.82Å; F57-A60 CarbonylContact O-C 3.55Å; F57-A60 WeakPolarHBondContact O-CA 3.42Å; F57-A60 VanDerWaalsContact O-CB 3.28Å; F57-A60 WeakPolarHBondContact O-CB 3.47Å; F57-A60 PolarHBondContact O-N 2.77Å; F57-E147 WeakPolarHBondContact CE2-OE2 3.35Å; F57-I218 HydrophobicContact CE1-CG2 4.33Å
58	S	43.2	Very low	43.2	Very low	82 Å²	82	93.3 Å²	93.3	57%	0.573	51%	0.514	S	S	*	.	H	α-helix	trans	-72.4	-26.5	177.5	73.2	0	0	0	0	113.2	R54 K55 A60	R54-S58 WeakPolarHBondContact O-CA 3.41Å; R54-S58 WeakPolarHBondContact O-CB 3.37Å; R54-S58 PolarHBondContact O-N 3.24Å; R54-S58 PolarHBondContact O-OG 3.32Å; K55-S58 PolarHBondContact O-OG 3.45Å; S58-A60 PolarHBondContact O-N 2.85Å
59	E	41.3	Very low	44	Very low	175 Å²	175	94.9 Å²	94.9	82%	0.818	53%	0.531	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.5	-10.7	168.4	-70.3	-176.6	172.1	0	0	111.5	F57	F57-E59 VanDerWaalsContact C-N 3.33Å; F57-E59 PolarHBondContact O-N 2.82Å
60	A	44.3	Very low	45	Very low	44 Å²	44	94.3 Å²	94.3	36%	0.364	52%	0.523	S	S	.	.	T	Hydrogen-bonded Turn	trans	-104.4	38.1	179.1	0	0	0	0	0	114	F57 S58 R221	F57-A60 CarbonylContact O-C 3.55Å; F57-A60 WeakPolarHBondContact O-CA 3.42Å; F57-A60 VanDerWaalsContact O-CB 3.28Å; F57-A60 WeakPolarHBondContact O-CB 3.47Å; F57-A60 PolarHBondContact O-N 2.77Å; S58-A60 PolarHBondContact O-N 2.85Å; A60-R221 PolarHBondContact O-NH2 3.44Å; A60-R221 VanDerWaalsContact O-NH2 3.11Å
61	A	36.3	Very low	45.6	Very low	64 Å²	64	94.5 Å²	94.5	53%	0.529	52%	0.521	S	S	.	.			trans	-47.6	153.7	175.4	0	0	0	0	0	114.1	N63 R221	A61-N63 PolarHBondContact O-N 3.42Å; A61-R221 PolarHBondContact O-NH2 3.02Å
62	P	40.3	Very low	46.7	Very low	128 Å²	128	94.2 Å²	94.2	83%	0.831	52%	0.522	S	S	*	.			trans	-83.9	78.2	-157.5	35	-34.5	0	0	0	111.4
63	N	37.8	Very low	48.5	Very low	137 Å²	137	98.2 Å²	98.2	73%	0.733	54%	0.536	S	S	*	.			trans	-89.4	120.1	153.9	-77.4	-32.1	0	0	0	107.5	A61 V65 R221	A61-N63 PolarHBondContact O-N 3.42Å; N63-V65 PolarHBondContact O-N 2.77Å; N63-R221 PolarHBondContact O-NH1 2.78Å
64	A	45	Very low	50.7	Low	97 Å²	97	97.8 Å²	97.8	80%	0.802	53%	0.531	S	S	*	.			trans	-38.5	122.8	178.5	0	0	0	0	0	110.4	K66	A64-K66 PolarHBondContact O-N 3.49Å
65	V	49.1	Very low	53	Low	68 Å²	68	92.5 Å²	92.5	41%	0.412	52%	0.519	S	S	.	.			trans	-52.4	116.2	173.1	179.1	0	0	0	0	106.5	N63 K67	N63-V65 PolarHBondContact O-N 2.77Å; V65-K67 VanDerWaalsContact C-N 3.32Å; V65-K67 PolarHBondContact O-N 3.21Å
66	K	40.4	Very low	55.4	Low	203 Å²	203	85.2 Å²	85.2	88%	0.883	49%	0.487	S	S	*	.			trans	-63.2	98.1	173.1	-97.3	-176.4	172.8	-179.5	0	106.7	A64 S68	A64-K66 PolarHBondContact O-N 3.49Å; K66-S68 PolarHBondContact O-N 2.64Å
67	K	50.6	Low	57.4	Low	88 Å²	88	81.3 Å²	81.3	38%	0.383	47%	0.467	S	S	.	.			trans	-57.6	129.9	171.2	-69.3	-177.2	179.4	-179.2	0	107.7	V65 E72	V65-K67 VanDerWaalsContact C-N 3.32Å; V65-K67 PolarHBondContact O-N 3.21Å; K67-E72 HydrophobicContact CB-CG 4.16Å; K67-E72 HydrophobicContact CD-CG 4.48Å
68	S	55.5	Low	59.5	Low	50 Å²	50	85.9 Å²	85.9	35%	0.35	49%	0.487	S	S	.	.			trans	-67.7	151.3	169.7	61.2	0	0	0	0	109.2	K66 S70 E71 E72	K66-S68 PolarHBondContact O-N 2.64Å; S68-S70 PolarHBondContact O-N 3.45Å; S68-S70 PolarHBondContact OG-OG 3.41Å; S68-E71 PolarHBondContact N-OE2 2.91Å; S68-E71 PolarHBondContact O-N 3.48Å; S68-E71 VanDerWaalsContact OG-CG 3.28Å; S68-E71 WeakPolarHBondContact OG-CG 3.19Å; S68-E71 PolarHBondContact OG-OE2 3.11Å; S68-E71 VanDerWaalsContact OG-OE2 3.11Å; S68-E72 PolarHBondContact O-N 2.92Å
69	S	54.7	Low	61.5	Low	104 Å²	104	89 Å²	89	73%	0.727	49%	0.492	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.4	-24.2	-178.8	56.8	0	0	0	0	113.4
70	S	58.5	Low	63.2	Low	53 Å²	53	83.6 Å²	83.6	37%	0.371	47%	0.469	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.1	-28.6	174.3	45.9	0	0	0	0	114	S68 E72 E73 N286	S68-S70 PolarHBondContact O-N 3.45Å; S68-S70 PolarHBondContact OG-OG 3.41Å; S70-E72 VanDerWaalsContact C-N 3.33Å; S70-E73 PolarHBondContact O-N 3.42Å; S70-N286 PolarHBondContact O-ND2 3.06Å
71	E	59.2	Low	64.6	Low	30 Å²	30	85.9 Å²	85.9	14%	0.14	48%	0.48	C	S	.	.	G	3₁₀ helix	trans	-76.1	-22.7	177.9	-76	170.4	148.5	0	0	112.5	S68 E73 E74 L77	S68-E71 PolarHBondContact N-OE2 2.91Å; S68-E71 PolarHBondContact O-N 3.48Å; S68-E71 VanDerWaalsContact OG-CG 3.28Å; S68-E71 WeakPolarHBondContact OG-CG 3.19Å; S68-E71 PolarHBondContact OG-OE2 3.11Å; S68-E71 VanDerWaalsContact OG-OE2 3.11Å; E71-E73 PolarHBondContact O-N 3Å; E71-E74 PolarHBondContact O-N 3.37Å; E71-L77 HydrophobicContact CB-CD1 4.47Å
72	E	60.5	Low	66.3	Low	121 Å²	121	93.7 Å²	93.7	57%	0.565	50%	0.496	S	S	*	.	G	3₁₀ helix	trans	-71	-18.3	174.8	-65.3	-173.3	167.7	0	0	113	K67 S68 S70	K67-E72 HydrophobicContact CB-CG 4.16Å; K67-E72 HydrophobicContact CD-CG 4.48Å; S68-E72 PolarHBondContact O-N 2.92Å; S70-E72 VanDerWaalsContact C-N 3.33Å
73	E	79.4	Confident	67.9	Low	146 Å²	146	88.8 Å²	88.8	68%	0.682	46%	0.461	S	S	*	.	G	3₁₀ helix	trans	-88.3	-13.7	176.9	-63.6	-168.1	160.3	0	0	113.3	S70 E71 P75	S70-E73 PolarHBondContact O-N 3.42Å; E71-E73 PolarHBondContact O-N 3Å; E73-P75 WeakPolarHBondContact O-CD 3.45Å
74	E	89.7	Confident	69.6	Low	6 Å²	6	91.4 Å²	91.4	3%	0.028	47%	0.466	C	S	.	.			trans	-68.7	121.1	-178.3	-70	-62	159.4	0	0	111.6	E71 L76 L77 K78 L284 V285 N286	E71-E74 PolarHBondContact O-N 3.37Å; E74-L76 PolarHBondContact O-N 3.01Å; E74-L76 VanDerWaalsContact O-N 3.1Å; E74-L77 HydrophobicContact CB-CB 4.1Å; E74-L77 HydrophobicContact CB-CD1 3.98Å; E74-L77 HydrophobicContact CB-CG 3.89Å; E74-L77 HydrophobicContact CG-CD1 4.2Å; E74-L77 PolarHBondContact O-N 2.86Å; E74-K78 PolarHBondContact O-N 2.64Å; E74-L284 HydrophobicContact CG-CD2 4.39Å; E74-V285 PolarHBondContact OE2-N 2.85Å; E74-N286 WeakPolarHBondContact OE1-CA 3.44Å; E74-N286 WeakPolarHBondContact OE1-CB 3.45Å; E74-N286 PolarHBondContact OE1-N 3.1Å; E74-N286 PolarHBondContact OE1-ND2 2.91Å
75	P	90.9	Very high	71.3	Confident	57 Å²	57	91.6 Å²	91.6	37%	0.37	46%	0.457	S	S	.	.	T	Hydrogen-bonded Turn	trans	-57.2	-31.1	-179.7	-25.4	34.3	0	0	0	113.4	E73 V285	E73-P75 WeakPolarHBondContact O-CD 3.45Å; P75-V285 HydrophobicContact CG-CG2 4.16Å
76	L	92.1	Very high	73.2	Confident	1 Å²	1	90.4 Å²	90.4	1%	0.005	45%	0.448	C	S	.	.	T	Hydrogen-bonded Turn	trans	-70.8	-29	179.5	-64.3	177.4	0	0	0	113.5	E74 V157 Q158 V159 Y225 M280 H283 L284	E74-L76 PolarHBondContact O-N 3.01Å; E74-L76 VanDerWaalsContact O-N 3.1Å; L76-V157 WeakPolarHBondContact O-CA 3.49Å; L76-Q158 PolarHBondContact O-N 3.21Å; L76-V159 HydrophobicContact CD2-CG2 3.92Å; L76-Y225 HydrophobicContact CD1-CE1 4.3Å; L76-M280 HydrophobicContact CD1-CE 3.71Å; L76-M280 WeakPolarHBondContact CD1-O 3.32Å; L76-M280 HydrophobicContact CD2-CE 3.71Å; L76-M280 HydrophobicContact CG-CE 4.19Å; L76-H283 HydrophobicContact CD1-CB 3.8Å; L76-H283 HydrophobicContact CD2-CB 3.98Å; L76-H283 HydrophobicContact CG-CB 4.08Å; L76-L284 HydrophobicContact CD1-CD2 4Å; L76-L284 HydrophobicContact CD1-CG 4.32Å
77	L	92.3	Very high	75.4	Confident	11 Å²	11	87.4 Å²	87.4	6%	0.058	44%	0.435	C	S	.	.	T	Hydrogen-bonded Turn	trans	-110.2	-11.1	-168.9	-50.9	-177.9	0	0	0	113	E71 E74 E156 V157 Q158 Y225	E71-L77 HydrophobicContact CB-CD1 4.47Å; E74-L77 HydrophobicContact CB-CB 4.1Å; E74-L77 HydrophobicContact CB-CD1 3.98Å; E74-L77 HydrophobicContact CB-CG 3.89Å; E74-L77 HydrophobicContact CG-CD1 4.2Å; E74-L77 PolarHBondContact O-N 2.86Å; L77-E156 HydrophobicContact CD2-CB 4.33Å; L77-V157 HydrophobicContact CD2-CG2 4.35Å; L77-Q158 WeakPolarHBondContact O-CG 3.46Å; L77-Y225 HydrophobicContact CD1-CD1 4.31Å; L77-Y225 HydrophobicContact CD1-CG 4.02Å; L77-Y225 HydrophobicContact CD2-CD1 4.21Å; L77-Y225 HydrophobicContact CD2-CD2 3.99Å; L77-Y225 HydrophobicContact CD2-CE1 4.36Å; L77-Y225 HydrophobicContact CD2-CE2 4.16Å; L77-Y225 HydrophobicContact CD2-CG 4.02Å
78	K	88.6	Confident	77.4	Confident	138 Å²	138	88 Å²	88	60%	0.6	45%	0.448	S	S	*	.	S	Bend	trans	-68.2	129.5	178.8	-172.7	174.8	-170.9	170.8	0	111.1	E74 N80 Q158	E74-K78 PolarHBondContact O-N 2.64Å; K78-N80 PolarHBondContact O-N 3.38Å; K78-Q158 WeakPolarHBondContact O-CB 3.42Å; K78-Q158 VanDerWaalsContact O-CG 3.32Å; K78-Q158 WeakPolarHBondContact O-CG 3.44Å
79	E	84.4	Confident	79.3	Confident	147 Å²	147	86.7 Å²	86.7	69%	0.687	44%	0.437	S	S	*	.			trans	-55.4	131.9	178.6	-69	-175.1	-178.9	0	0	111.7	P81	E79-P81 VanDerWaalsContact C-CD 3.46Å; E79-P81 WeakPolarHBondContact O-CD 3.46Å
80	N	76.9	Confident	81.1	Confident	63 Å²	63	87 Å²	87	34%	0.337	43%	0.427	S	S	.	.			trans	-123.8	70.1	180	-165.8	-6.8	0	0	0	110.8	K78 R82 R83	K78-N80 PolarHBondContact O-N 3.38Å; N80-R82 PolarHBondContact O-N 3.22Å; N80-R83 WeakPolarHBondContact ND2-CD 3.35Å; N80-R83 PolarHBondContact O-N 3.47Å
81	P	74.8	Confident	82.9	Confident	91 Å²	91	87 Å²	87	59%	0.591	42%	0.419	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.3	-7.5	-172.3	27.1	-35.8	0	0	0	114	E79 F84	E79-P81 VanDerWaalsContact C-CD 3.46Å; E79-P81 WeakPolarHBondContact O-CD 3.46Å; P81-F84 VanDerWaalsContact O-CE2 3.3Å; P81-F84 WeakPolarHBondContact O-CE2 3.46Å
82	R	71.6	Confident	84.7	Confident	229 Å²	229	91.9 Å²	91.9	86%	0.864	44%	0.442	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101.5	3.5	-176.3	-66.6	-172.4	-115.6	176.2	-2.1	113.8	N80	N80-R82 PolarHBondContact O-N 3.22Å
83	R	73.5	Confident	86.5	Confident	25 Å²	25	89 Å²	89	9%	0.094	43%	0.43	C	S	.	.			trans	-117.8	69	-171.5	-158.3	173.4	-172.2	-154.3	-8.7	113.4	N80 P88 T160 E161	N80-R83 WeakPolarHBondContact ND2-CD 3.35Å; N80-R83 PolarHBondContact O-N 3.47Å; R83-P88 PolarHBondContact NH2-O 2.8Å; R83-P88 VanDerWaalsContact NH2-O 3.16Å; R83-T160 WeakPolarHBondContact CD-OG1 3.49Å; R83-T160 WeakPolarHBondContact CG-OG1 3.45Å; R83-E161 IonicContact CZ-OE1 3.67Å; R83-E161 IonicContact CZ-OE2 2.67Å; R83-E161 VanDerWaalsContact CZ-OE2 3.27Å; R83-E161 IonicContact NH1-OE1 2.76Å; R83-E161 PolarHBondContact NH1-OE1 2.99Å; R83-E161 IonicContact NH1-OE2 3.82Å; R83-E161 PolarHBondContact NH1-OE2 3.5Å; R83-E161 IonicContact NH2-OE1 2.99Å; R83-E161 PolarHBondContact NH2-OE1 3.06Å; R83-E161 IonicContact NH2-OE2 3.53Å; R83-E161 PolarHBondContact NH2-OE2 2.75Å
84	F	73.3	Confident	87.4	Confident	191 Å²	191	82 Å²	82	84%	0.838	40%	0.397	S	S	*	.			trans	-89.1	-12.9	170.5	-67.9	-76	0	0	0	113.5	P81	P81-F84 VanDerWaalsContact O-CE2 3.3Å; P81-F84 WeakPolarHBondContact O-CE2 3.46Å
85	V	82.2	Confident	87.7	Confident	102 Å²	102	83.9 Å²	83.9	62%	0.618	40%	0.404	S	S	*	.	S	Bend	trans	-107.3	136.3	176.9	-66.7	0	0	0	0	109.4	F87	V85-F87 WeakPolarHBondContact CG2-O 3.27Å
86	I	87.6	Confident	88	Confident	43 Å²	43	87.4 Å²	87.4	22%	0.221	42%	0.416	C	S	.	.			trans	-67.9	-37.3	-177.1	-174.3	60.7	0	0	0	112	P88 I89 W95 T160 E161	I86-P88 CarbonylContact O-C 3.57Å; I86-I89 HydrophobicContact CD1-CD1 4.13Å; I86-I89 HydrophobicContact CG1-CD1 3.81Å; I86-W95 HydrophobicContact CD1-CE3 4.13Å; I86-W95 HydrophobicContact CD1-CH2 4.19Å; I86-W95 HydrophobicContact CD1-CZ3 3.65Å; I86-W95 HydrophobicContact CG1-CE3 4.47Å; I86-W95 HydrophobicContact CG1-CH2 3.8Å; I86-W95 HydrophobicContact CG1-CZ2 4.48Å; I86-W95 HydrophobicContact CG1-CZ3 3.8Å; I86-T160 HydrophobicContact CD1-CG2 3.7Å; I86-E161 HydrophobicContact CD1-CG 4.24Å
87	F	87.7	Confident	88.3	Confident	140 Å²	140	89 Å²	89	61%	0.614	42%	0.424	S	S	*	.	P	Polyproline II helix	trans	-88.5	146.1	179.1	-72.7	-73.9	0	0	0	112.6	V85 I89	V85-F87 WeakPolarHBondContact CG2-O 3.27Å; F87-I89 HydrophobicContact CD1-CD1 4.39Å; F87-I89 HydrophobicContact CD1-CG1 4.06Å; F87-I89 HydrophobicContact CE1-CD1 4.28Å; F87-I89 HydrophobicContact CE1-CG1 3.9Å
88	P	92.3	Very high	88.5	Confident	101 Å²	101	90.1 Å²	90.1	66%	0.656	43%	0.428	S	S	*	.	S	Bend	cis	-73.2	148.3	-5.6	30.6	-34.7	0	0	0	112.6	R83 I86 Q90	R83-P88 PolarHBondContact NH2-O 2.8Å; R83-P88 VanDerWaalsContact NH2-O 3.16Å; I86-P88 CarbonylContact O-C 3.57Å; P88-Q90 PolarHBondContact O-N 3.43Å
89	I	94.9	Very high	88.9	Confident	22 Å²	22	87.6 Å²	87.6	11%	0.113	42%	0.417	C	S	.	.	P	Polyproline II helix	trans	-65.6	132.5	174.4	-57.6	-60.2	0	0	0	108.9	I86 F87 H92 W95 E161	I86-I89 HydrophobicContact CD1-CD1 4.13Å; I86-I89 HydrophobicContact CG1-CD1 3.81Å; F87-I89 HydrophobicContact CD1-CD1 4.39Å; F87-I89 HydrophobicContact CD1-CG1 4.06Å; F87-I89 HydrophobicContact CE1-CD1 4.28Å; F87-I89 HydrophobicContact CE1-CG1 3.9Å; I89-H92 PolarHBondContact O-CE1 3.48Å; I89-W95 HydrophobicContact CD1-CD2 3.7Å; I89-W95 HydrophobicContact CD1-CE3 4.1Å; I89-W95 HydrophobicContact CD1-CG 3.93Å; I89-W95 HydrophobicContact CD1-CZ2 4.32Å; I89-W95 HydrophobicContact CG1-CG 4.3Å; I89-W95 HydrophobicContact CG2-CB 3.86Å; I89-W95 HydrophobicContact CG2-CG 4.14Å; I89-E161 HydrophobicContact CD1-CG 4.41Å; I89-E161 HydrophobicContact CG2-CG 4.3Å
90	Q	93	Very high	89.4	Confident	111 Å²	111	85.3 Å²	85.3	52%	0.519	40%	0.404	S	S	.	.	S	Bend	trans	-106.2	-46.3	178.8	-65.7	-178.1	-3	0	0	110.1	P88 H92 E161	P88-Q90 PolarHBondContact O-N 3.43Å; Q90-H92 PolarHBondContact O-ND1 2.81Å; Q90-E161 PolarHBondContact N-OE1 3.23Å
91	Y	95.8	Very high	90.2	Very high	53 Å²	53	82.5 Å²	82.5	21%	0.208	39%	0.39	C	S	.	.			trans	-102.4	86.4	179.2	-66.1	-90.4	0	0	0	110.1	D93 I94 W95 V159 E161 H283	Y91-D93 VanDerWaalsContact C-N 3.34Å; Y91-D93 PolarHBondContact O-N 2.96Å; Y91-I94 HydrophobicContact CD1-CD1 3.92Å; Y91-I94 HydrophobicContact CG-CD1 3.9Å; Y91-I94 PolarHBondContact O-N 3.46Å; Y91-W95 WeakPolarHBondContact O-CB 3.35Å; Y91-W95 PolarHBondContact O-N 3.27Å; Y91-V159 HydrophobicContact CD2-CG1 3.49Å; Y91-V159 VanDerWaalsContact CD2-CG1 3.49Å; Y91-V159 HydrophobicContact CD2-CG2 4.35Å; Y91-V159 HydrophobicContact CE2-CG1 3.87Å; Y91-V159 HydrophobicContact CE2-CG2 3.86Å; Y91-V159 HydrophobicContact CG-CG1 4.14Å; Y91-E161 PolarHBondContact N-OE1 3.45Å; Y91-H283 AromaticContact CD1-CE1 3.69Å; Y91-H283 AromaticContact CE1-CE1 3.9Å; Y91-H283 AromaticContact CE1-ND1 3.82Å
92	H	97.3	Very high	91.2	Very high	131 Å²	131	81.5 Å²	81.5	61%	0.606	38%	0.378	S	S	*	.	H	α-helix	trans	-67.7	-34.2	-174.4	-69.5	75.6	0	0	0	112.8	I89 Q90 W95 Q96	I89-H92 PolarHBondContact O-CE1 3.48Å; Q90-H92 PolarHBondContact O-ND1 2.81Å; H92-W95 PolarHBondContact O-N 2.75Å; H92-Q96 WeakPolarHBondContact O-CB 3.48Å; H92-Q96 PolarHBondContact O-N 3.01Å
93	D	97.7	Very high	92.1	Very high	60 Å²	60	73.5 Å²	73.5	32%	0.321	36%	0.36	S	S	.	.	H	α-helix	trans	-65.2	-46	174.7	54.2	-14.3	0	0	0	112.2	Y91 Q96 M97 L279 H283	Y91-D93 VanDerWaalsContact C-N 3.34Å; Y91-D93 PolarHBondContact O-N 2.96Å; D93-Q96 PolarHBondContact O-N 3.42Å; D93-M97 PolarHBondContact O-N 3.18Å; D93-M97 VanDerWaalsContact O-N 3.13Å; D93-L279 HydrophobicContact CB-CD1 4.49Å; D93-L279 HydrophobicContact CB-CD2 4.49Å; D93-H283 IonicContact OD1-NE2 2.64Å; D93-H283 IonicContact OD2-CD2 3.13Å; D93-H283 IonicContact OD2-CE1 3.26Å; D93-H283 PolarHBondContact OD2-CE1 3.07Å; D93-H283 IonicContact OD2-NE2 3.58Å; D93-H283 PolarHBondContact OD2-NE2 3.17Å
94	I	97.9	Very high	92.9	Very high	0 Å²	0	73 Å²	73	0%	0	36%	0.361	C	S	.	.	H	α-helix	trans	-63	-44.7	174.2	-61.1	-177.5	0	0	0	110	Y91 Q96 M97 Y98 V159 E161 A162 F276 L279 M280	Y91-I94 HydrophobicContact CD1-CD1 3.92Å; Y91-I94 HydrophobicContact CG-CD1 3.9Å; Y91-I94 PolarHBondContact O-N 3.46Å; I94-Q96 VanDerWaalsContact C-N 3.32Å; I94-Q96 PolarHBondContact O-N 3.49Å; I94-M97 WeakPolarHBondContact O-CB 3.4Å; I94-M97 PolarHBondContact O-N 3.33Å; I94-Y98 PolarHBondContact O-N 3.36Å; I94-V159 HydrophobicContact CD1-CG1 4.36Å; I94-E161 HydrophobicContact CB-CB 4.12Å; I94-E161 HydrophobicContact CG2-CB 3.63Å; I94-A162 HydrophobicContact CG2-CB 3.93Å; I94-F276 HydrophobicContact CG2-CE2 3.81Å; I94-F276 HydrophobicContact CG2-CZ 4.09Å; I94-L279 HydrophobicContact CG1-CD2 4.01Å; I94-L279 HydrophobicContact CG1-CG 4.45Å; I94-M280 HydrophobicContact CD1-SD 4.1Å
95	W	97.7	Very high	93.9	Very high	45 Å²	45	68 Å²	68	17%	0.17	34%	0.338	C	S	.	.	H	α-helix	trans	-63.1	-37.6	177.6	-171	-113.5	0	0	0	112.8	I86 I89 Y91 H92 M97 Y98 K99 E161 C164	I86-W95 HydrophobicContact CD1-CE3 4.13Å; I86-W95 HydrophobicContact CD1-CH2 4.19Å; I86-W95 HydrophobicContact CD1-CZ3 3.65Å; I86-W95 HydrophobicContact CG1-CE3 4.47Å; I86-W95 HydrophobicContact CG1-CH2 3.8Å; I86-W95 HydrophobicContact CG1-CZ2 4.48Å; I86-W95 HydrophobicContact CG1-CZ3 3.8Å; I89-W95 HydrophobicContact CD1-CD2 3.7Å; I89-W95 HydrophobicContact CD1-CE3 4.1Å; I89-W95 HydrophobicContact CD1-CG 3.93Å; I89-W95 HydrophobicContact CD1-CZ2 4.32Å; I89-W95 HydrophobicContact CG1-CG 4.3Å; I89-W95 HydrophobicContact CG2-CB 3.86Å; I89-W95 HydrophobicContact CG2-CG 4.14Å; Y91-W95 WeakPolarHBondContact O-CB 3.35Å; Y91-W95 PolarHBondContact O-N 3.27Å; H92-W95 PolarHBondContact O-N 2.75Å; W95-M97 VanDerWaalsContact C-N 3.34Å; W95-Y98 HydrophobicContact CD2-CD1 4.03Å; W95-Y98 AromaticContact CE3-CD1 3.62Å; W95-Y98 HydrophobicContact CE3-CD1 3.62Å; W95-Y98 HydrophobicContact CE3-CE1 4.36Å; W95-Y98 HydrophobicContact CE3-CG 4.28Å; W95-Y98 AromaticContact CH2-CD1 3.58Å; W95-Y98 HydrophobicContact CH2-CD1 3.58Å; W95-Y98 AromaticContact CH2-CE1 3.45Å; W95-Y98 HydrophobicContact CH2-CE1 3.45Å; W95-Y98 VanDerWaalsContact CH2-CE1 3.45Å; W95-Y98 AromaticContact CZ2-CD1 3.99Å; W95-Y98 HydrophobicContact CZ2-CD1 3.99Å; W95-Y98 AromaticContact CZ2-CE1 3.95Å; W95-Y98 HydrophobicContact CZ2-CE1 3.95Å; W95-Y98 AromaticContact CZ3-CD1 3.38Å; W95-Y98 HydrophobicContact CZ3-CD1 3.38Å; W95-Y98 AromaticContact CZ3-CE1 3.69Å; W95-Y98 HydrophobicContact CZ3-CE1 3.69Å; W95-Y98 HydrophobicContact CZ3-CG 4.18Å; W95-Y98 WeakPolarHBondContact O-CB 3.27Å; W95-Y98 PolarHBondContact O-N 3.43Å; W95-K99 VanDerWaalsContact CZ2-CE 3.46Å; W95-K99 WeakPolarHBondContact O-CG 3.4Å; W95-K99 PolarHBondContact O-N 2.86Å; W95-E161 HydrophobicContact CB-CG 4.16Å; W95-E161 HydrophobicContact CE3-CB 4.23Å; W95-E161 HydrophobicContact CE3-CG 4.03Å; W95-C164 HydrophobicContact CZ3-CB 3.91Å
96	Q	97.5	Very high	94.6	Very high	132 Å²	132	63.1 Å²	63.1	62%	0.617	31%	0.309	S	S	*	.	H	α-helix	trans	-64.2	-39.2	176.1	-173.2	-179.9	8.1	0	0	111.6	H92 D93 I94 K99 K100	H92-Q96 WeakPolarHBondContact O-CB 3.48Å; H92-Q96 PolarHBondContact O-N 3.01Å; D93-Q96 PolarHBondContact O-N 3.42Å; I94-Q96 VanDerWaalsContact C-N 3.32Å; I94-Q96 PolarHBondContact O-N 3.49Å; Q96-K99 PolarHBondContact O-N 2.94Å; Q96-K100 WeakPolarHBondContact O-CB 3.36Å; Q96-K100 PolarHBondContact O-N 3.03Å
97	M	96.9	Very high	95.1	Very high	35 Å²	35	63 Å²	63	17%	0.172	31%	0.31	C	S	.	.	H	α-helix	trans	-62.3	-42.4	172.1	-69.9	-67	102.3	0	0	111.5	D93 I94 W95 K99 K100 A101 F165 L272 F276 L279	D93-M97 PolarHBondContact O-N 3.18Å; D93-M97 VanDerWaalsContact O-N 3.13Å; I94-M97 WeakPolarHBondContact O-CB 3.4Å; I94-M97 PolarHBondContact O-N 3.33Å; W95-M97 VanDerWaalsContact C-N 3.34Å; M97-K99 PolarHBondContact O-N 3.17Å; M97-K100 HydrophobicContact CE-CD 4.05Å; M97-K100 WeakPolarHBondContact O-CB 3.47Å; M97-K100 PolarHBondContact O-N 2.56Å; M97-A101 PolarHBondContact O-N 3.12Å; M97-F165 HydrophobicContact CB-CD2 3.93Å; M97-F165 HydrophobicContact CB-CE2 3.9Å; M97-L272 HydrophobicContact SD-CD1 3.86Å; M97-F276 HydrophobicContact CB-CD2 3.85Å; M97-F276 HydrophobicContact CB-CE2 4.33Å; M97-F276 HydrophobicContact CG-CD2 4.24Å; M97-L279 HydrophobicContact CG-CD2 3.69Å
98	Y	97.9	Very high	95.5	Very high	34 Å²	34	56.4 Å²	56.4	13%	0.133	28%	0.282	C	S	.	.	H	α-helix	trans	-59.5	-46.3	174.6	163.7	-105.2	0	0	0	111.5	I94 W95 K100 A101 E102 C164 F168	I94-Y98 PolarHBondContact O-N 3.36Å; W95-Y98 HydrophobicContact CD2-CD1 4.03Å; W95-Y98 AromaticContact CE3-CD1 3.62Å; W95-Y98 HydrophobicContact CE3-CD1 3.62Å; W95-Y98 HydrophobicContact CE3-CE1 4.36Å; W95-Y98 HydrophobicContact CE3-CG 4.28Å; W95-Y98 AromaticContact CH2-CD1 3.58Å; W95-Y98 HydrophobicContact CH2-CD1 3.58Å; W95-Y98 AromaticContact CH2-CE1 3.45Å; W95-Y98 HydrophobicContact CH2-CE1 3.45Å; W95-Y98 VanDerWaalsContact CH2-CE1 3.45Å; W95-Y98 AromaticContact CZ2-CD1 3.99Å; W95-Y98 HydrophobicContact CZ2-CD1 3.99Å; W95-Y98 AromaticContact CZ2-CE1 3.95Å; W95-Y98 HydrophobicContact CZ2-CE1 3.95Å; W95-Y98 AromaticContact CZ3-CD1 3.38Å; W95-Y98 HydrophobicContact CZ3-CD1 3.38Å; W95-Y98 AromaticContact CZ3-CE1 3.69Å; W95-Y98 HydrophobicContact CZ3-CE1 3.69Å; W95-Y98 HydrophobicContact CZ3-CG 4.18Å; W95-Y98 WeakPolarHBondContact O-CB 3.27Å; W95-Y98 PolarHBondContact O-N 3.43Å; Y98-K100 VanDerWaalsContact C-N 3.3Å; Y98-K100 PolarHBondContact O-N 3.36Å; Y98-A101 WeakPolarHBondContact O-CB 3.23Å; Y98-A101 PolarHBondContact O-N 3.2Å; Y98-A101 VanDerWaalsContact O-N 3.16Å; Y98-E102 WeakPolarHBondContact O-CB 3.42Å; Y98-E102 PolarHBondContact O-N 3.42Å; Y98-E102 PolarHBondContact OH-OE1 3.3Å; Y98-C164 HydrophobicContact CD1-CB 4.4Å; Y98-C164 HydrophobicContact CD2-CB 3.86Å; Y98-C164 WeakPolarHBondContact CD2-O 3.34Å; Y98-C164 HydrophobicContact CE2-CB 4.04Å; Y98-C164 HydrophobicContact CG-CB 4.05Å; Y98-F168 HydrophobicContact CD2-CB 4.34Å; Y98-F168 HydrophobicContact CE2-CB 4.14Å
99	K	97.1	Very high	95.7	Very high	85 Å²	85	58.5 Å²	58.5	37%	0.37	28%	0.283	S	S	.	.	H	α-helix	trans	-64.4	-33.9	176.9	-69.6	-56.7	-174.7	-180	0	113.2	W95 Q96 M97 E102 A103	W95-K99 VanDerWaalsContact CZ2-CE 3.46Å; W95-K99 WeakPolarHBondContact O-CG 3.4Å; W95-K99 PolarHBondContact O-N 2.86Å; Q96-K99 PolarHBondContact O-N 2.94Å; M97-K99 PolarHBondContact O-N 3.17Å; K99-E102 WeakPolarHBondContact CD-OE2 3.35Å; K99-E102 WeakPolarHBondContact CE-OE2 3.36Å; K99-E102 IonicContact NZ-OE1 3.47Å; K99-E102 IonicContact NZ-OE2 2.6Å; K99-E102 PolarHBondContact NZ-OE2 3.46Å; K99-A103 WeakPolarHBondContact O-CB 3.33Å; K99-A103 PolarHBondContact O-N 3.29Å
100	K	93.3	Very high	95.6	Very high	98 Å²	98	61.8 Å²	61.8	43%	0.426	30%	0.298	S	S	.	.	H	α-helix	trans	-65.8	-40.5	172.8	-173.5	179.3	170	-160.4	0	111.4	Q96 M97 Y98 S104 L272	Q96-K100 WeakPolarHBondContact O-CB 3.36Å; Q96-K100 PolarHBondContact O-N 3.03Å; M97-K100 HydrophobicContact CE-CD 4.05Å; M97-K100 WeakPolarHBondContact O-CB 3.47Å; M97-K100 PolarHBondContact O-N 2.56Å; Y98-K100 VanDerWaalsContact C-N 3.3Å; Y98-K100 PolarHBondContact O-N 3.36Å; K100-S104 PolarHBondContact O-N 3.45Å; K100-S104 PolarHBondContact O-OG 2.98Å; K100-L272 HydrophobicContact CD-CD1 3.69Å; K100-L272 HydrophobicContact CG-CD1 4.18Å; K100-L272 HydrophobicContact CG-CD2 4.29Å
101	A	93.9	Very high	95.7	Very high	5 Å²	5	56.9 Å²	56.9	4%	0.041	28%	0.276	C	S	.	.	H	α-helix	trans	-65.4	-49.9	174.8	0	0	0	0	0	111	M97 Y98 A103 S104 F105 F165 F168 L272	M97-A101 PolarHBondContact O-N 3.12Å; Y98-A101 WeakPolarHBondContact O-CB 3.23Å; Y98-A101 PolarHBondContact O-N 3.2Å; Y98-A101 VanDerWaalsContact O-N 3.16Å; A101-A103 VanDerWaalsContact C-N 3.31Å; A101-A103 PolarHBondContact O-N 2.93Å; A101-S104 WeakPolarHBondContact O-CA 3.4Å; A101-S104 WeakPolarHBondContact O-CB 3.35Å; A101-S104 PolarHBondContact O-N 3.19Å; A101-F105 PolarHBondContact O-N 3.4Å; A101-F165 HydrophobicContact CB-CD2 4.4Å; A101-F165 HydrophobicContact CB-CE2 3.97Å; A101-F168 HydrophobicContact CB-CD1 3.69Å; A101-F168 HydrophobicContact CB-CE1 4.05Å; A101-F168 WeakPolarHBondContact O-CE1 3.04Å; A101-L272 VanDerWaalsContact CA-CD2 3.49Å; A101-L272 HydrophobicContact CB-CD2 3.66Å
102	E	95.7	Very high	95.7	Very high	70 Å²	70	59.2 Å²	59.2	33%	0.327	29%	0.292	S	S	.	.	H	α-helix	trans	-56.6	-42	178.5	-173.1	180	-128.9	0	0	112.2	Y98 K99 S104 F105 F168	Y98-E102 WeakPolarHBondContact O-CB 3.42Å; Y98-E102 PolarHBondContact O-N 3.42Å; Y98-E102 PolarHBondContact OH-OE1 3.3Å; K99-E102 WeakPolarHBondContact CD-OE2 3.35Å; K99-E102 WeakPolarHBondContact CE-OE2 3.36Å; K99-E102 IonicContact NZ-OE1 3.47Å; K99-E102 IonicContact NZ-OE2 2.6Å; K99-E102 PolarHBondContact NZ-OE2 3.46Å; E102-S104 PolarHBondContact O-N 3.31Å; E102-F105 WeakPolarHBondContact O-CB 3.37Å; E102-F105 PolarHBondContact O-N 3.38Å; E102-F168 HydrophobicContact CB-CE2 4.47Å
103	A	91.4	Very high	95.6	Very high	60 Å²	60	54 Å²	54	50%	0.496	27%	0.268	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67.2	-16.3	176.5	0	0	0	0	0	113.9	K99 A101	K99-A103 WeakPolarHBondContact O-CB 3.33Å; K99-A103 PolarHBondContact O-N 3.29Å; A101-A103 VanDerWaalsContact C-N 3.31Å; A101-A103 PolarHBondContact O-N 2.93Å
104	S	90.3	Very high	95.4	Very high	15 Å²	15	55.3 Å²	55.3	11%	0.105	28%	0.282	C	S	.	.	T	Hydrogen-bonded Turn	trans	-97.2	0.1	-177.2	-55.9	0	0	0	0	113.2	K100 A101 E102 W106 R268	K100-S104 PolarHBondContact O-N 3.45Å; K100-S104 PolarHBondContact O-OG 2.98Å; A101-S104 WeakPolarHBondContact O-CA 3.4Å; A101-S104 WeakPolarHBondContact O-CB 3.35Å; A101-S104 PolarHBondContact O-N 3.19Å; E102-S104 PolarHBondContact O-N 3.31Å; S104-W106 PolarHBondContact O-N 2.88Å; S104-R268 PolarHBondContact O-NH2 3.46Å
105	F	94.1	Very high	95.3	Very high	85 Å²	85	61.3 Å²	61.3	37%	0.373	31%	0.308	S	S	.	.			trans	-46.1	134.6	-179.6	-179.2	-104.8	0	0	0	113.6	A101 E102 T107 F168 M172 I175 R369	A101-F105 PolarHBondContact O-N 3.4Å; E102-F105 WeakPolarHBondContact O-CB 3.37Å; E102-F105 PolarHBondContact O-N 3.38Å; F105-T107 HydrophobicContact CE1-CG2 3.73Å; F105-T107 HydrophobicContact CZ-CG2 3.65Å; F105-F168 HydrophobicContact CB-CZ 3.86Å; F105-F168 HydrophobicContact CD2-CE2 4.15Å; F105-F168 AromaticContact CD2-CZ 3.86Å; F105-F168 HydrophobicContact CD2-CZ 3.86Å; F105-F168 HydrophobicContact CG-CZ 4.34Å; F105-M172 HydrophobicContact CD2-SD 3.93Å; F105-M172 HydrophobicContact CE2-SD 4.42Å; F105-I175 HydrophobicContact CE2-CD1 3.95Å; F105-R369 PolarHBondContact O-NH1 3.31Å; F105-R369 PolarHBondContact O-NH2 3.39Å
106	W	96.9	Very high	95.2	Very high	0 Å²	0	59.1 Å²	59.1	0%	0	30%	0.3	C	S	.	.			trans	-149	161.5	174.5	61.5	-77.9	0	0	0	109.9	S104 E110 V111 M172 I175 H176 M179 L265 I266 R268 D269	S104-W106 PolarHBondContact O-N 2.88Å; W106-E110 WeakPolarHBondContact CA-OE1 3.5Å; W106-V111 HydrophobicContact CE3-CG2 4.44Å; W106-V111 HydrophobicContact CZ3-CG2 4.05Å; W106-M172 HydrophobicContact CD2-CE 4.33Å; W106-M172 HydrophobicContact CG-CE 4.09Å; W106-I175 HydrophobicContact CD2-CG2 4.37Å; W106-I175 HydrophobicContact CE3-CG2 4.2Å; W106-I175 HydrophobicContact CH2-CG2 4.02Å; W106-I175 HydrophobicContact CZ2-CG2 4.22Å; W106-I175 HydrophobicContact CZ3-CG2 4.02Å; W106-I175 WeakPolarHBondContact O-CD1 3.42Å; W106-H176 AromaticContact CZ2-CD2 3.56Å; W106-H176 AromaticContact CZ2-NE2 3.94Å; W106-M179 HydrophobicContact CH2-CB 4.11Å; W106-M179 HydrophobicContact CH2-CG 4.04Å; W106-M179 HydrophobicContact CZ3-CB 4.5Å; W106-M179 HydrophobicContact CZ3-CG 4.27Å; W106-M179 HydrophobicContact CZ3-SD 4.2Å; W106-L265 HydrophobicContact CD2-CB 4.03Å; W106-L265 HydrophobicContact CD2-CD1 3.69Å; W106-L265 HydrophobicContact CD2-CG 4.41Å; W106-L265 HydrophobicContact CE3-CD1 3.61Å; W106-L265 HydrophobicContact CG-CB 4.46Å; W106-L265 HydrophobicContact CG-CD1 4.1Å; W106-L265 HydrophobicContact CH2-CB 4.43Å; W106-L265 HydrophobicContact CZ2-CB 3.89Å; W106-L265 HydrophobicContact CZ3-CD1 4.1Å; W106-I266 HydrophobicContact CH2-CD1 4.36Å; W106-I266 HydrophobicContact CH2-CG1 3.94Å; W106-I266 HydrophobicContact CZ2-CG1 3.67Å; W106-R268 VanDerWaalsContact CD1-NH2 3.3Å; W106-D269 PolarHBondContact NE1-OD2 3.2Å
107	T	97.3	Very high	95.1	Very high	41 Å²	41	55.4 Å²	55.4	25%	0.252	28%	0.284	S	S	.	.			trans	-119.7	158.3	174.2	79	0	0	0	0	112.4	F105 E109 E110	F105-T107 HydrophobicContact CE1-CG2 3.73Å; F105-T107 HydrophobicContact CZ-CG2 3.65Å; T107-E109 WeakPolarHBondContact CB-OE2 3.36Å; T107-E109 PolarHBondContact O-N 3.04Å; T107-E109 PolarHBondContact OG1-OE2 3.39Å; T107-E110 PolarHBondContact N-OE1 2.76Å; T107-E110 WeakPolarHBondContact O-CB 3.46Å; T107-E110 PolarHBondContact O-N 3.01Å
108	A	97.1	Very high	95	Very high	2 Å²	2	60.8 Å²	60.8	2%	0.017	31%	0.309	C	S	.	.	G	3₁₀ helix	trans	-59.3	-29.4	-178.5	0	0	0	0	0	112.7	E110 V111 E178 M179	A108-E110 PolarHBondContact O-N 2.88Å; A108-V111 PolarHBondContact O-N 3Å; A108-V111 VanDerWaalsContact O-N 3.13Å; A108-E178 HydrophobicContact CB-CG 4.09Å; A108-M179 HydrophobicContact CB-SD 4.15Å
109	E	96.2	Very high	95	Very high	144 Å²	144	61.5 Å²	61.5	67%	0.673	31%	0.313	S	S	*	.	G	3₁₀ helix	trans	-67.7	-17.8	177.1	-60.1	79.8	-175.3	0	0	114	T107 V111	T107-E109 WeakPolarHBondContact CB-OE2 3.36Å; T107-E109 PolarHBondContact O-N 3.04Å; T107-E109 PolarHBondContact OG1-OE2 3.39Å; E109-V111 PolarHBondContact O-N 3.15Å
110	E	93.2	Very high	95.1	Very high	91 Å²	91	58.5 Å²	58.5	43%	0.425	30%	0.299	S	S	.	.	G	3₁₀ helix	trans	-70.2	-14.1	173	-67.4	176.8	-127.9	0	0	112.1	W106 T107 A108 R369	W106-E110 WeakPolarHBondContact CA-OE1 3.5Å; T107-E110 PolarHBondContact N-OE1 2.76Å; T107-E110 WeakPolarHBondContact O-CB 3.46Å; T107-E110 PolarHBondContact O-N 3.01Å; A108-E110 PolarHBondContact O-N 2.88Å; E110-R369 IonicContact OE1-NH2 3.21Å; E110-R369 IonicContact OE2-NH2 3.11Å; E110-R369 PolarHBondContact OE2-NH2 3.28Å; E110-R369 VanDerWaalsContact OE2-NH2 3.07Å
111	V	94.9	Very high	95.2	Very high	9 Å²	9	59.3 Å²	59.3	6%	0.055	30%	0.304	C	S	.	.	S	Bend	trans	-95.9	108.7	-177.2	-176.3	0	0	0	0	110.8	W106 A108 E109 L113 M179 G258 F261 L265	W106-V111 HydrophobicContact CE3-CG2 4.44Å; W106-V111 HydrophobicContact CZ3-CG2 4.05Å; A108-V111 PolarHBondContact O-N 3Å; A108-V111 VanDerWaalsContact O-N 3.13Å; E109-V111 PolarHBondContact O-N 3.15Å; V111-L113 HydrophobicContact CG1-CD2 3.79Å; V111-L113 HydrophobicContact CG1-CG 4.47Å; V111-L113 PolarHBondContact O-N 3.22Å; V111-M179 HydrophobicContact CB-CE 4.11Å; V111-M179 HydrophobicContact CB-SD 3.8Å; V111-M179 HydrophobicContact CG1-CE 3.92Å; V111-M179 HydrophobicContact CG1-SD 4.11Å; V111-M179 HydrophobicContact CG2-SD 3.66Å; V111-G258 WeakPolarHBondContact CG1-O 3.37Å; V111-F261 HydrophobicContact CG1-CD1 4.3Å; V111-F261 HydrophobicContact CG2-CD1 4.15Å; V111-F261 HydrophobicContact CG2-CE1 4.29Å; V111-L265 HydrophobicContact CG2-CD1 4.25Å
112	D	94.6	Very high	95.3	Very high	102 Å²	102	63.1 Å²	63.1	55%	0.545	33%	0.331	S	S	.	.			trans	-77	110.8	175.4	179	17.7	0	0	0	111.8	S114	D112-S114 VanDerWaalsContact CG-OG 3.27Å; D112-S114 WeakPolarHBondContact OD1-CB 3.15Å; D112-S114 PolarHBondContact OD1-N 2.64Å; D112-S114 PolarHBondContact OD1-OG 3.11Å; D112-S114 PolarHBondContact OD2-OG 3.49Å; D112-S114 VanDerWaalsContact OD2-OG 3.12Å
113	L	96.4	Very high	95.3	Very high	20 Å²	20	60.3 Å²	60.3	11%	0.105	32%	0.318	C	S	.	.			trans	-97.3	4.4	175.8	-57.2	-175	0	0	0	113.7	V111 K115 D116 M179 L182 L183 T186	V111-L113 HydrophobicContact CG1-CD2 3.79Å; V111-L113 HydrophobicContact CG1-CG 4.47Å; V111-L113 PolarHBondContact O-N 3.22Å; L113-K115 PolarHBondContact O-N 3.27Å; L113-K115 VanDerWaalsContact O-N 3.13Å; L113-D116 PolarHBondContact O-N 2.68Å; L113-D116 VanDerWaalsContact O-N 3.08Å; L113-M179 HydrophobicContact CD1-CE 4.04Å; L113-M179 HydrophobicContact CD2-CE 4.17Å; L113-M179 HydrophobicContact CG-CE 4.42Å; L113-L182 HydrophobicContact CD1-CD2 3.93Å; L113-L182 HydrophobicContact CD1-CG 3.74Å; L113-L183 HydrophobicContact CD1-CD2 4.25Å; L113-L183 HydrophobicContact CD2-CD2 3.73Å; L113-T186 HydrophobicContact CB-CG2 4.43Å; L113-T186 HydrophobicContact CD1-CG2 4.41Å
114	S	94.1	Very high	95.6	Very high	88 Å²	88	64.2 Å²	64.2	62%	0.615	32%	0.324	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.5	-30	-170.9	63.4	0	0	0	0	114.2	D112	D112-S114 VanDerWaalsContact CG-OG 3.27Å; D112-S114 WeakPolarHBondContact OD1-CB 3.15Å; D112-S114 PolarHBondContact OD1-N 2.64Å; D112-S114 PolarHBondContact OD1-OG 3.11Å; D112-S114 PolarHBondContact OD2-OG 3.49Å; D112-S114 VanDerWaalsContact OD2-OG 3.12Å
115	K	94.8	Very high	95.9	Very high	126 Å²	126	68.9 Å²	68.9	55%	0.548	35%	0.348	S	S	.	.	T	Hydrogen-bonded Turn	trans	-92.4	-20.1	179.6	-64	-179.5	-175.7	172	0	113.2	L113 L117 Q118 H119 P257	L113-K115 PolarHBondContact O-N 3.27Å; L113-K115 VanDerWaalsContact O-N 3.13Å; K115-L117 VanDerWaalsContact C-N 3.3Å; K115-L117 PolarHBondContact O-N 2.88Å; K115-Q118 PolarHBondContact O-N 3.31Å; K115-H119 PolarHBondContact O-CD2 3.15Å; K115-H119 VanDerWaalsContact O-CD2 3.26Å; K115-H119 PolarHBondContact O-N 3.26Å; K115-P257 HydrophobicContact CB-CG 4.13Å
116	D	96	Very high	96.1	Very high	0 Å²	0	69.2 Å²	69.2	0%	0	35%	0.353	C	S	.	.	H	α-helix	trans	-66.6	-33.9	-169.8	-79	-125.7	0	0	0	112.3	L113 Q118 H119 W120 Y187 M256 P257 G258 L259	L113-D116 PolarHBondContact O-N 2.68Å; L113-D116 VanDerWaalsContact O-N 3.08Å; D116-Q118 VanDerWaalsContact C-N 3.31Å; D116-Q118 PolarHBondContact O-N 3.44Å; D116-H119 CarbonylContact O-C 3.59Å; D116-H119 WeakPolarHBondContact O-CB 3.43Å; D116-H119 PolarHBondContact O-N 3.33Å; D116-H119 VanDerWaalsContact O-N 3.14Å; D116-W120 WeakPolarHBondContact O-CB 3.3Å; D116-W120 PolarHBondContact O-N 3.35Å; D116-Y187 HydrophobicContact CB-CE1 3.6Å; D116-Y187 PolarHBondContact OD1-OH 3.35Å; D116-M256 HydrophobicContact CB-CE 4Å; D116-P257 WeakPolarHBondContact OD2-CD 3.27Å; D116-P257 WeakPolarHBondContact OD2-CG 3Å; D116-G258 VanDerWaalsContact CG-N 3.32Å; D116-G258 WeakPolarHBondContact OD1-CA 3.44Å; D116-G258 PolarHBondContact OD1-N 3.05Å; D116-G258 VanDerWaalsContact OD1-N 3.16Å; D116-G258 WeakPolarHBondContact OD2-CA 3.16Å; D116-G258 PolarHBondContact OD2-N 3.45Å; D116-L259 PolarHBondContact OD1-N 3.41Å
117	L	94.8	Very high	96.1	Very high	53 Å²	53	69.7 Å²	69.7	28%	0.277	36%	0.355	S	S	.	.	H	α-helix	trans	-63.4	-39	179.8	-172.3	61.5	0	0	0	112.2	K115 H119 W120 E121	K115-L117 VanDerWaalsContact C-N 3.3Å; K115-L117 PolarHBondContact O-N 2.88Å; L117-H119 VanDerWaalsContact C-N 3.34Å; L117-W120 WeakPolarHBondContact O-CB 3.33Å; L117-W120 PolarHBondContact O-N 2.93Å; L117-E121 WeakPolarHBondContact O-CG 3.21Å; L117-E121 PolarHBondContact O-N 3.05Å
118	Q	96	Very high	96	Very high	149 Å²	149	70.9 Å²	70.9	70%	0.696	36%	0.355	S	S	*	.	H	α-helix	trans	-65	-41.1	174.9	-176.3	-177.5	3.3	0	0	111.1	K115 D116 S122	K115-Q118 PolarHBondContact O-N 3.31Å; D116-Q118 VanDerWaalsContact C-N 3.31Å; D116-Q118 PolarHBondContact O-N 3.44Å; Q118-S122 PolarHBondContact O-N 3.47Å
119	H	97.6	Very high	95.9	Very high	49 Å²	49	76 Å²	76	23%	0.227	38%	0.375	C	S	.	.	H	α-helix	trans	-64.2	-45.7	175.9	-77.6	-121.4	0	0	0	110.7	K115 D116 L117 E121 S122 L123 M256	K115-H119 PolarHBondContact O-CD2 3.15Å; K115-H119 VanDerWaalsContact O-CD2 3.26Å; K115-H119 PolarHBondContact O-N 3.26Å; D116-H119 CarbonylContact O-C 3.59Å; D116-H119 WeakPolarHBondContact O-CB 3.43Å; D116-H119 PolarHBondContact O-N 3.33Å; D116-H119 VanDerWaalsContact O-N 3.14Å; L117-H119 VanDerWaalsContact C-N 3.34Å; H119-E121 VanDerWaalsContact C-N 3.34Å; H119-E121 PolarHBondContact O-N 3.08Å; H119-S122 WeakPolarHBondContact O-CA 3.39Å; H119-S122 WeakPolarHBondContact O-CB 3.47Å; H119-S122 PolarHBondContact O-N 2.93Å; H119-S122 PolarHBondContact O-OG 3.07Å; H119-L123 WeakPolarHBondContact O-CG 3.41Å; H119-L123 PolarHBondContact O-N 3.41Å; H119-M256 HydrophobicContact CB-SD 3.53Å; H119-M256 VanDerWaalsContact CB-SD 3.53Å; H119-M256 PolarHBondContact ND1-N 3.34Å
120	W	97.6	Very high	95.9	Very high	21 Å²	21	69.3 Å²	69.3	8%	0.08	34%	0.344	C	S	.	.	H	α-helix	trans	-54.7	-47.6	178.9	179.6	-107.9	0	0	0	112.2	D116 L117 S122 L123 R128 I131 Y187 I188 M256	D116-W120 WeakPolarHBondContact O-CB 3.3Å; D116-W120 PolarHBondContact O-N 3.35Å; L117-W120 WeakPolarHBondContact O-CB 3.33Å; L117-W120 PolarHBondContact O-N 2.93Å; W120-S122 PolarHBondContact O-N 3.47Å; W120-L123 HydrophobicContact CE3-CD1 3.86Å; W120-L123 HydrophobicContact CZ3-CD1 4.31Å; W120-L123 WeakPolarHBondContact O-CB 3.33Å; W120-L123 PolarHBondContact O-N 3.45Å; W120-R128 HydrophobicContact CD2-CG 3.99Å; W120-R128 VanDerWaalsContact CE2-CD 3.46Å; W120-R128 HydrophobicContact CE3-CG 4.06Å; W120-R128 HydrophobicContact CH2-CB 3.62Å; W120-R128 HydrophobicContact CH2-CG 3.87Å; W120-R128 WeakPolarHBondContact CH2-O 3.43Å; W120-R128 HydrophobicContact CZ2-CB 3.72Å; W120-R128 HydrophobicContact CZ2-CG 3.79Å; W120-R128 HydrophobicContact CZ3-CB 4.12Å; W120-R128 HydrophobicContact CZ3-CG 4Å; W120-R128 WeakPolarHBondContact O-CD 3.5Å; W120-I131 HydrophobicContact CH2-CB 4.44Å; W120-I131 HydrophobicContact CH2-CG2 4.49Å; W120-I131 HydrophobicContact CZ3-CB 3.89Å; W120-I131 HydrophobicContact CZ3-CD1 4.24Å; W120-I131 HydrophobicContact CZ3-CG2 3.78Å; W120-Y187 HydrophobicContact CD2-CG 4.16Å; W120-Y187 HydrophobicContact CE3-CD2 4.25Å; W120-Y187 HydrophobicContact CE3-CG 4.14Å; W120-Y187 HydrophobicContact CZ3-CD2 4.32Å; W120-Y187 PolarHBondContact NE1-O 3.39Å; W120-I188 HydrophobicContact CH2-CD1 4.29Å; W120-I188 HydrophobicContact CZ2-CD1 3.7Å; W120-M256 HydrophobicContact CB-CE 4.11Å; W120-M256 HydrophobicContact CB-SD 4.26Å; W120-M256 HydrophobicContact CE3-CE 4.01Å
121	E	95.6	Very high	96	Very high	115 Å²	115	65.2 Å²	65.2	54%	0.537	33%	0.325	S	S	.	.	H	α-helix	trans	-64.7	-24.9	178	-70.5	175.9	176.1	0	0	112.6	L117 H119 K189	L117-E121 WeakPolarHBondContact O-CG 3.21Å; L117-E121 PolarHBondContact O-N 3.05Å; H119-E121 VanDerWaalsContact C-N 3.34Å; H119-E121 PolarHBondContact O-N 3.08Å; E121-K189 IonicContact OE1-NZ 2.77Å; E121-K189 PolarHBondContact OE1-NZ 3.18Å
122	S	96.3	Very high	96	Very high	86 Å²	86	64.9 Å²	64.9	60%	0.601	32%	0.323	S	S	*	.	H	α-helix	trans	-86.5	-12.1	177.1	78.1	0	0	0	0	115	Q118 H119 W120	Q118-S122 PolarHBondContact O-N 3.47Å; H119-S122 WeakPolarHBondContact O-CA 3.39Å; H119-S122 WeakPolarHBondContact O-CB 3.47Å; H119-S122 PolarHBondContact O-N 2.93Å; H119-S122 PolarHBondContact O-OG 3.07Å; W120-S122 PolarHBondContact O-N 3.47Å
123	L	97	Very high	95.9	Very high	10 Å²	10	60.8 Å²	60.8	5%	0.052	30%	0.3	C	S	.	.	S	Bend	trans	-68.6	162	179.8	-69	179.6	0	0	0	111.8	H119 W120 E127 R128 I131 L255 M256	H119-L123 WeakPolarHBondContact O-CG 3.41Å; H119-L123 PolarHBondContact O-N 3.41Å; W120-L123 HydrophobicContact CE3-CD1 3.86Å; W120-L123 HydrophobicContact CZ3-CD1 4.31Å; W120-L123 WeakPolarHBondContact O-CB 3.33Å; W120-L123 PolarHBondContact O-N 3.45Å; L123-E127 HydrophobicContact CB-CB 4.2Å; L123-E127 HydrophobicContact CD2-CB 4.45Å; L123-R128 HydrophobicContact CB-CG 3.81Å; L123-R128 HydrophobicContact CD1-CG 4.28Å; L123-R128 PolarHBondContact O-NH1 2.93Å; L123-I131 HydrophobicContact CD1-CD1 3.58Å; L123-L255 HydrophobicContact CD2-CD1 3.93Å; L123-L255 HydrophobicContact CD2-CD2 4.46Å; L123-M256 HydrophobicContact CD1-CG 4.24Å; L123-M256 HydrophobicContact CD1-SD 3.94Å
124	K	97.1	Very high	95.7	Very high	143 Å²	143	59.9 Å²	59.9	62%	0.622	30%	0.296	S	S	*	.			trans	-75.8	156.6	168.3	-60.7	175.4	-175.4	175.2	0	110.7	D126 E127 R128	K124-D126 VanDerWaalsContact C-N 3.27Å; K124-D126 PolarHBondContact O-N 3.18Å; K124-E127 HydrophobicContact CB-CG 4.12Å; K124-E127 PolarHBondContact N-OE2 3.44Å; K124-E127 WeakPolarHBondContact O-CB 3.42Å; K124-E127 PolarHBondContact O-N 3.38Å; K124-R128 PolarHBondContact O-N 2.97Å
125	D	96.9	Very high	95.7	Very high	113 Å²	113	55.9 Å²	55.9	60%	0.604	27%	0.267	S	S	*	.	H	α-helix	trans	-55.7	-42.9	177.7	-62.1	9.9	0	0	0	111.6	E127 R128 Y129	D125-E127 VanDerWaalsContact C-N 3.33Å; D125-E127 PolarHBondContact O-N 3.45Å; D125-R128 PolarHBondContact O-N 3.02Å; D125-R128 IonicContact OD1-CZ 3.83Å; D125-R128 IonicContact OD1-NH1 3.07Å; D125-R128 IonicContact OD1-NH2 3.05Å; D125-R128 PolarHBondContact OD1-NH2 3.21Å; D125-Y129 VanDerWaalsContact O-CB 3.3Å; D125-Y129 WeakPolarHBondContact O-CB 3.4Å; D125-Y129 PolarHBondContact O-N 2.99Å
126	D	96.8	Very high	95.4	Very high	92 Å²	92	49.9 Å²	49.9	49%	0.492	24%	0.242	S	C	.	.	H	α-helix	trans	-62.2	-37.3	176.4	-71.3	-13	0	0	0	112.9	K124 F130 L316	K124-D126 VanDerWaalsContact C-N 3.27Å; K124-D126 PolarHBondContact O-N 3.18Å; D126-F130 WeakPolarHBondContact O-CB 3.42Å; D126-F130 PolarHBondContact O-N 2.97Å; D126-L316 HydrophobicContact CB-CB 4.27Å; D126-L316 HydrophobicContact CB-CD2 3.88Å
127	E	97.1	Very high	95	Very high	9 Å²	9	50 Å²	50	4%	0.042	24%	0.242	C	C	.	.	H	α-helix	trans	-71.9	-43.1	179	-64.3	174	141.8	0	0	110.7	L123 K124 D125 F130 I131 R253 I317	L123-E127 HydrophobicContact CB-CB 4.2Å; L123-E127 HydrophobicContact CD2-CB 4.45Å; K124-E127 HydrophobicContact CB-CG 4.12Å; K124-E127 PolarHBondContact N-OE2 3.44Å; K124-E127 WeakPolarHBondContact O-CB 3.42Å; K124-E127 PolarHBondContact O-N 3.38Å; D125-E127 VanDerWaalsContact C-N 3.33Å; D125-E127 PolarHBondContact O-N 3.45Å; E127-F130 PolarHBondContact O-N 3.34Å; E127-I131 WeakPolarHBondContact O-CB 3.48Å; E127-I131 WeakPolarHBondContact O-CD1 3.43Å; E127-I131 VanDerWaalsContact O-CG1 3.23Å; E127-I131 WeakPolarHBondContact O-CG1 3.42Å; E127-I131 PolarHBondContact O-N 3.33Å; E127-R253 IonicContact OE1-CZ 3.27Å; E127-R253 IonicContact OE1-NH1 3.19Å; E127-R253 PolarHBondContact OE1-NH1 3.28Å; E127-R253 IonicContact OE1-NH2 2.73Å; E127-R253 PolarHBondContact OE1-NH2 3.4Å; E127-I317 HydrophobicContact CB-CG2 4.41Å; E127-I317 HydrophobicContact CG-CG2 4.28Å
128	R	96.8	Very high	94.8	Very high	66 Å²	66	47.4 Å²	47.4	25%	0.249	23%	0.229	C	C	.	.	H	α-helix	trans	-61.6	-44.7	173.6	-70.1	-162.4	-60.7	-83.1	-2.8	111.2	W120 L123 K124 D125 F130 I131 S132	W120-R128 HydrophobicContact CD2-CG 3.99Å; W120-R128 VanDerWaalsContact CE2-CD 3.46Å; W120-R128 HydrophobicContact CE3-CG 4.06Å; W120-R128 HydrophobicContact CH2-CB 3.62Å; W120-R128 HydrophobicContact CH2-CG 3.87Å; W120-R128 WeakPolarHBondContact CH2-O 3.43Å; W120-R128 HydrophobicContact CZ2-CB 3.72Å; W120-R128 HydrophobicContact CZ2-CG 3.79Å; W120-R128 HydrophobicContact CZ3-CB 4.12Å; W120-R128 HydrophobicContact CZ3-CG 4Å; W120-R128 WeakPolarHBondContact O-CD 3.5Å; L123-R128 HydrophobicContact CB-CG 3.81Å; L123-R128 HydrophobicContact CD1-CG 4.28Å; L123-R128 PolarHBondContact O-NH1 2.93Å; K124-R128 PolarHBondContact O-N 2.97Å; D125-R128 PolarHBondContact O-N 3.02Å; D125-R128 IonicContact OD1-CZ 3.83Å; D125-R128 IonicContact OD1-NH1 3.07Å; D125-R128 IonicContact OD1-NH2 3.05Å; D125-R128 PolarHBondContact OD1-NH2 3.21Å; R128-F130 PolarHBondContact O-N 3.4Å; R128-I131 PolarHBondContact O-N 2.98Å; R128-S132 WeakPolarHBondContact O-CB 3.26Å; R128-S132 PolarHBondContact O-N 3.06Å; R128-S132 PolarHBondContact O-OG 3.49Å; R128-S132 VanDerWaalsContact O-OG 3.13Å
129	Y	94.6	Very high	94.4	Very high	111 Å²	111	41.4 Å²	41.4	44%	0.435	21%	0.205	S	C	.	.	H	α-helix	trans	-58.3	-47.8	176.2	179	-92.5	0	0	0	111.4	D125 S132 H133 L312 L316	D125-Y129 VanDerWaalsContact O-CB 3.3Å; D125-Y129 WeakPolarHBondContact O-CB 3.4Å; D125-Y129 PolarHBondContact O-N 2.99Å; Y129-S132 PolarHBondContact O-OG 2.91Å; Y129-S132 VanDerWaalsContact O-OG 3.1Å; Y129-H133 AromaticContact CD2-CE1 3.44Å; Y129-H133 VanDerWaalsContact CD2-CE1 3.44Å; Y129-H133 WeakPolarHBondContact CD2-CE1 3.44Å; Y129-H133 AromaticContact CD2-ND1 3.83Å; Y129-H133 AromaticContact CE2-CE1 3.08Å; Y129-H133 WeakPolarHBondContact CE2-CE1 3.47Å; Y129-H133 AromaticContact CE2-ND1 3.76Å; Y129-H133 AromaticContact CE2-NE2 3.38Å; Y129-H133 WeakPolarHBondContact CE2-NE2 3.21Å; Y129-H133 AromaticContact CZ-CD2 3.95Å; Y129-H133 AromaticContact CZ-CE1 3.59Å; Y129-H133 AromaticContact CZ-NE2 3.53Å; Y129-H133 WeakPolarHBondContact O-CB 3.45Å; Y129-H133 PolarHBondContact O-N 3.36Å; Y129-H133 PolarHBondContact O-ND1 2.86Å; Y129-H133 PolarHBondContact OH-NE2 2.97Å; Y129-L312 HydrophobicContact CD1-CD1 4.1Å; Y129-L312 HydrophobicContact CE1-CD1 3.7Å; Y129-L316 HydrophobicContact CD1-CD1 3.97Å; Y129-L316 HydrophobicContact CE1-CD1 4.31Å
130	F	95.6	Very high	93.7	Very high	2 Å²	2	39.8 Å²	39.8	1%	0.009	20%	0.2	C	C	.	.	H	α-helix	trans	-59.7	-51.6	177.4	-177.6	-86.4	0	0	0	111.7	D126 E127 R128 H133 V134 A246 L308 L312 V314 L316 I317	D126-F130 WeakPolarHBondContact O-CB 3.42Å; D126-F130 PolarHBondContact O-N 2.97Å; E127-F130 PolarHBondContact O-N 3.34Å; R128-F130 PolarHBondContact O-N 3.4Å; F130-H133 PolarHBondContact O-N 3.07Å; F130-V134 HydrophobicContact CD1-CG2 4.08Å; F130-V134 HydrophobicContact CE1-CG2 3.62Å; F130-V134 HydrophobicContact CE2-CG2 4.48Å; F130-V134 HydrophobicContact CZ-CG2 3.84Å; F130-V134 WeakPolarHBondContact O-CG2 3.5Å; F130-V134 PolarHBondContact O-N 3.21Å; F130-A246 HydrophobicContact CE1-CB 3.73Å; F130-A246 HydrophobicContact CZ-CB 3.7Å; F130-L308 HydrophobicContact CZ-CD2 4.35Å; F130-L312 HydrophobicContact CD2-CD1 4.3Å; F130-L312 HydrophobicContact CD2-CD2 4.29Å; F130-L312 HydrophobicContact CD2-CG 3.76Å; F130-L312 HydrophobicContact CE2-CD2 4.34Å; F130-L312 HydrophobicContact CE2-CG 3.97Å; F130-L312 WeakPolarHBondContact CE2-O 3.47Å; F130-V314 HydrophobicContact CE2-CB 4.42Å; F130-V314 HydrophobicContact CE2-CG1 3.93Å; F130-V314 HydrophobicContact CZ-CG1 3.98Å; F130-L316 HydrophobicContact CB-CB 4.09Å; F130-L316 HydrophobicContact CB-CD1 4.37Å; F130-L316 HydrophobicContact CD2-CB 4.23Å; F130-L316 HydrophobicContact CD2-CD1 4.25Å; F130-I317 HydrophobicContact CB-CG2 3.77Å; F130-I317 HydrophobicContact CD1-CD1 4.01Å; F130-I317 HydrophobicContact CD1-CG1 4.34Å; F130-I317 HydrophobicContact CD1-CG2 3.51Å; F130-I317 HydrophobicContact CD2-CG2 4.46Å; F130-I317 HydrophobicContact CE1-CD1 3.61Å; F130-I317 HydrophobicContact CE1-CG1 4.3Å; F130-I317 HydrophobicContact CE1-CG2 4.25Å; F130-I317 HydrophobicContact CG-CG2 3.65Å; F130-I317 HydrophobicContact CZ-CD1 3.93Å; F130-I317 HydrophobicContact CZ-CG1 4.47Å
131	I	96.3	Very high	93.1	Very high	5 Å²	5	39.3 Å²	39.3	3%	0.026	20%	0.2	C	C	.	.	H	α-helix	trans	-64.4	-44.6	-176.7	-65.9	163.4	0	0	0	111	W120 L123 E127 R128 H133 V134 L135 L250 L259	W120-I131 HydrophobicContact CH2-CB 4.44Å; W120-I131 HydrophobicContact CH2-CG2 4.49Å; W120-I131 HydrophobicContact CZ3-CB 3.89Å; W120-I131 HydrophobicContact CZ3-CD1 4.24Å; W120-I131 HydrophobicContact CZ3-CG2 3.78Å; L123-I131 HydrophobicContact CD1-CD1 3.58Å; E127-I131 WeakPolarHBondContact O-CB 3.48Å; E127-I131 WeakPolarHBondContact O-CD1 3.43Å; E127-I131 VanDerWaalsContact O-CG1 3.23Å; E127-I131 WeakPolarHBondContact O-CG1 3.42Å; E127-I131 PolarHBondContact O-N 3.33Å; R128-I131 PolarHBondContact O-N 2.98Å; I131-H133 VanDerWaalsContact C-N 3.3Å; I131-H133 PolarHBondContact O-N 2.93Å; I131-V134 PolarHBondContact O-N 2.97Å; I131-L135 HydrophobicContact CG2-CD1 3.91Å; I131-L135 HydrophobicContact CG2-CG 4.29Å; I131-L135 WeakPolarHBondContact O-CG 3.31Å; I131-L135 PolarHBondContact O-N 3.4Å; I131-L250 HydrophobicContact CD1-CD1 3.57Å; I131-L250 HydrophobicContact CG1-CD1 3.8Å; I131-L259 HydrophobicContact CG2-CD2 3.78Å
132	S	94.2	Very high	92.4	Very high	3 Å²	3	34 Å²	34	2%	0.021	18%	0.175	C	C	.	.	H	α-helix	trans	-61.9	-38.9	-178.9	66.9	0	0	0	0	112.2	R128 Y129 A136	R128-S132 WeakPolarHBondContact O-CB 3.26Å; R128-S132 PolarHBondContact O-N 3.06Å; R128-S132 PolarHBondContact O-OG 3.49Å; R128-S132 VanDerWaalsContact O-OG 3.13Å; Y129-S132 PolarHBondContact O-OG 2.91Å; Y129-S132 VanDerWaalsContact O-OG 3.1Å; S132-A136 WeakPolarHBondContact O-CB 3.28Å; S132-A136 PolarHBondContact O-N 3Å
133	H	91.6	Very high	91.9	Very high	15 Å²	15	31.5 Å²	31.5	7%	0.069	16%	0.162	C	C	.	.	H	α-helix	trans	-75	-34.1	178.7	-72.8	62.3	0	0	0	112.6	Y129 F130 I131 F137 L312	Y129-H133 AromaticContact CD2-CE1 3.44Å; Y129-H133 VanDerWaalsContact CD2-CE1 3.44Å; Y129-H133 WeakPolarHBondContact CD2-CE1 3.44Å; Y129-H133 AromaticContact CD2-ND1 3.83Å; Y129-H133 AromaticContact CE2-CE1 3.08Å; Y129-H133 WeakPolarHBondContact CE2-CE1 3.47Å; Y129-H133 AromaticContact CE2-ND1 3.76Å; Y129-H133 AromaticContact CE2-NE2 3.38Å; Y129-H133 WeakPolarHBondContact CE2-NE2 3.21Å; Y129-H133 AromaticContact CZ-CD2 3.95Å; Y129-H133 AromaticContact CZ-CE1 3.59Å; Y129-H133 AromaticContact CZ-NE2 3.53Å; Y129-H133 WeakPolarHBondContact O-CB 3.45Å; Y129-H133 PolarHBondContact O-N 3.36Å; Y129-H133 PolarHBondContact O-ND1 2.86Å; Y129-H133 PolarHBondContact OH-NE2 2.97Å; F130-H133 PolarHBondContact O-N 3.07Å; I131-H133 VanDerWaalsContact C-N 3.3Å; I131-H133 PolarHBondContact O-N 2.93Å; H133-F137 WeakPolarHBondContact O-CB 3.47Å; H133-F137 PolarHBondContact O-N 3.28Å; H133-L312 HydrophobicContact CB-CD1 3.75Å; H133-L312 HydrophobicContact CB-CD2 3.65Å; H133-L312 HydrophobicContact CB-CG 4.37Å
134	V	93.3	Very high	91.2	Very high	2 Å²	2	31.6 Å²	31.6	1%	0.012	16%	0.163	C	C	.	.	H	α-helix	trans	-63	-46.2	170.9	167.5	0	0	0	0	110.8	F130 I131 A136 F137 F138 I247 L312	F130-V134 HydrophobicContact CD1-CG2 4.08Å; F130-V134 HydrophobicContact CE1-CG2 3.62Å; F130-V134 HydrophobicContact CE2-CG2 4.48Å; F130-V134 HydrophobicContact CZ-CG2 3.84Å; F130-V134 WeakPolarHBondContact O-CG2 3.5Å; F130-V134 PolarHBondContact O-N 3.21Å; I131-V134 PolarHBondContact O-N 2.97Å; V134-A136 VanDerWaalsContact C-N 3.34Å; V134-A136 PolarHBondContact O-N 3.41Å; V134-F137 WeakPolarHBondContact O-CB 3.43Å; V134-F137 PolarHBondContact O-N 3.41Å; V134-F138 HydrophobicContact CG1-CD2 3.65Å; V134-F138 HydrophobicContact CG1-CE2 3.31Å; V134-F138 HydrophobicContact CG1-CZ 4.23Å; V134-F138 VanDerWaalsContact O-CD2 3.3Å; V134-F138 WeakPolarHBondContact O-CD2 3.3Å; V134-F138 PolarHBondContact O-N 3.01Å; V134-I247 HydrophobicContact CG1-CD1 4.24Å; V134-L312 HydrophobicContact CG2-CD2 3.6Å
135	L	93.6	Very high	90.6	Very high	3 Å²	3	25.1 Å²	25.1	2%	0.016	14%	0.135	C	C	.	.	H	α-helix	trans	-63	-40.8	178	-69.5	173.9	0	0	0	112.1	I131 F137 F138 A139 Y180 L183 I184 Y187 L259	I131-L135 HydrophobicContact CG2-CD1 3.91Å; I131-L135 HydrophobicContact CG2-CG 4.29Å; I131-L135 WeakPolarHBondContact O-CG 3.31Å; I131-L135 PolarHBondContact O-N 3.4Å; L135-F137 VanDerWaalsContact C-N 3.31Å; L135-F137 PolarHBondContact O-N 3.19Å; L135-F138 PolarHBondContact O-N 3.38Å; L135-A139 WeakPolarHBondContact O-CB 3.21Å; L135-A139 PolarHBondContact O-N 3.19Å; L135-Y180 HydrophobicContact CD2-CD1 3.82Å; L135-Y180 HydrophobicContact CD2-CE1 4.32Å; L135-L183 HydrophobicContact CD1-CB 4.05Å; L135-L183 HydrophobicContact CD2-CB 4.14Å; L135-L183 HydrophobicContact CD2-CD1 3.82Å; L135-I184 HydrophobicContact CB-CD1 4.14Å; L135-I184 HydrophobicContact CB-CG1 3.77Å; L135-I184 HydrophobicContact CD1-CG1 4.4Å; L135-Y187 HydrophobicContact CD1-CD2 3.74Å; L135-Y187 HydrophobicContact CD1-CE2 3.92Å; L135-L259 HydrophobicContact CD2-CD1 3.87Å
136	A	88.8	Confident	90.1	Very high	1 Å²	1	20.7 Å²	20.7	1%	0.008	11%	0.111	C	C	.	.	H	α-helix	trans	-62.6	-39.1	175.9	0	0	0	0	0	112.3	S132 V134 A140 L197 A200	S132-A136 WeakPolarHBondContact O-CB 3.28Å; S132-A136 PolarHBondContact O-N 3Å; V134-A136 VanDerWaalsContact C-N 3.34Å; V134-A136 PolarHBondContact O-N 3.41Å; A136-A140 WeakPolarHBondContact O-CB 3.11Å; A136-A140 PolarHBondContact O-N 3.47Å; A136-L197 HydrophobicContact CB-CB 3.89Å; A136-L197 HydrophobicContact CB-CD2 3.86Å; A136-L197 HydrophobicContact CB-CG 4.43Å; A136-L197 WeakPolarHBondContact CB-O 3.35Å; A136-A200 HydrophobicContact CB-CB 4.08Å
137	F	87.6	Confident	89.5	Confident	1 Å²	1	19.1 Å²	19.1	0%	0.004	10%	0.101	C	C	.	.	H	α-helix	trans	-62.8	-46.6	173.4	167.9	-106.9	0	0	0	112	H133 V134 L135 A140 S141 V207 K210 F240 F307	H133-F137 WeakPolarHBondContact O-CB 3.47Å; H133-F137 PolarHBondContact O-N 3.28Å; V134-F137 WeakPolarHBondContact O-CB 3.43Å; V134-F137 PolarHBondContact O-N 3.41Å; L135-F137 VanDerWaalsContact C-N 3.31Å; L135-F137 PolarHBondContact O-N 3.19Å; F137-A140 PolarHBondContact O-N 3.5Å; F137-S141 WeakPolarHBondContact CD2-OG 3.44Å; F137-S141 WeakPolarHBondContact CE2-OG 3.4Å; F137-S141 WeakPolarHBondContact CZ-OG 3.48Å; F137-S141 WeakPolarHBondContact O-CB 3.32Å; F137-S141 PolarHBondContact O-N 3.34Å; F137-S141 PolarHBondContact O-OG 3.47Å; F137-V207 HydrophobicContact CB-CG2 3.94Å; F137-V207 HydrophobicContact CD2-CB 4.32Å; F137-V207 HydrophobicContact CD2-CG1 3.99Å; F137-V207 HydrophobicContact CD2-CG2 3.97Å; F137-V207 HydrophobicContact CG-CG2 4.42Å; F137-K210 HydrophobicContact CD2-CD 4.19Å; F137-K210 HydrophobicContact CE1-CD 4.28Å; F137-K210 HydrophobicContact CE2-CB 3.92Å; F137-K210 HydrophobicContact CE2-CD 3.26Å; F137-K210 HydrophobicContact CE2-CG 4.25Å; F137-K210 HydrophobicContact CZ-CD 3.33Å; F137-F240 HydrophobicContact CD1-CE1 4.5Å; F137-F240 AromaticContact CE1-CD1 3.63Å; F137-F240 HydrophobicContact CE1-CD1 3.63Å; F137-F240 AromaticContact CE1-CE1 3.63Å; F137-F240 HydrophobicContact CE1-CE1 3.63Å; F137-F240 HydrophobicContact CZ-CD1 4.17Å; F137-F240 AromaticContact CZ-CE1 3.88Å; F137-F240 HydrophobicContact CZ-CE1 3.88Å; F137-F307 HydrophobicContact CB-CZ 4.11Å; F137-F307 HydrophobicContact CD1-CE1 4.36Å; F137-F307 HydrophobicContact CD1-CZ 4.2Å; F137-F307 HydrophobicContact CD2-CZ 4.46Å; F137-F307 HydrophobicContact CG-CE2 4.48Å; F137-F307 AromaticContact CG-CZ 3.98Å; F137-F307 HydrophobicContact CG-CZ 3.98Å
138	F	90.4	Very high	89	Confident	0 Å²	0	19.2 Å²	19.2	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-61.4	-51.1	177.9	-76.8	-52.9	0	0	0	112.2	V134 L135 A140 S141 D142 Y180 F240 F244 I247	V134-F138 HydrophobicContact CG1-CD2 3.65Å; V134-F138 HydrophobicContact CG1-CE2 3.31Å; V134-F138 HydrophobicContact CG1-CZ 4.23Å; V134-F138 VanDerWaalsContact O-CD2 3.3Å; V134-F138 WeakPolarHBondContact O-CD2 3.3Å; V134-F138 PolarHBondContact O-N 3.01Å; L135-F138 PolarHBondContact O-N 3.38Å; F138-A140 PolarHBondContact O-N 2.89Å; F138-A140 VanDerWaalsContact O-N 3.11Å; F138-S141 PolarHBondContact O-N 3.3Å; F138-D142 PolarHBondContact O-N 3.13Å; F138-D142 VanDerWaalsContact O-N 3.11Å; F138-Y180 HydrophobicContact CB-CD1 3.75Å; F138-Y180 HydrophobicContact CB-CD2 3.72Å; F138-Y180 HydrophobicContact CB-CE1 3.6Å; F138-Y180 HydrophobicContact CB-CE2 3.57Å; F138-Y180 HydrophobicContact CB-CG 3.81Å; F138-Y180 VanDerWaalsContact CB-CZ 3.48Å; F138-Y180 HydrophobicContact CD1-CE1 4.43Å; F138-Y180 HydrophobicContact CD1-CE2 4.33Å; F138-Y180 AromaticContact CD1-CZ 3.86Å; F138-Y180 WeakPolarHBondContact CD1-OH 2.99Å; F138-Y180 HydrophobicContact CD2-CD1 4.17Å; F138-Y180 AromaticContact CD2-CE1 3.46Å; F138-Y180 HydrophobicContact CD2-CE1 3.46Å; F138-Y180 VanDerWaalsContact CD2-CE1 3.46Å; F138-Y180 AromaticContact CD2-CZ 3.73Å; F138-Y180 HydrophobicContact CE2-CE1 4.16Å; F138-Y180 HydrophobicContact CG-CD1 4.26Å; F138-Y180 AromaticContact CG-CE1 3.62Å; F138-Y180 HydrophobicContact CG-CE1 3.62Å; F138-Y180 HydrophobicContact CG-CE2 4.01Å; F138-Y180 AromaticContact CG-CZ 3.46Å; F138-Y180 VanDerWaalsContact CG-CZ 3.46Å; F138-F240 AromaticContact CD1-CD1 3.53Å; F138-F240 HydrophobicContact CD1-CD1 3.53Å; F138-F240 AromaticContact CD1-CE1 3.67Å; F138-F240 HydrophobicContact CD1-CE1 3.67Å; F138-F240 HydrophobicContact CD1-CG 4.39Å; F138-F240 HydrophobicContact CE1-CB 3.98Å; F138-F240 AromaticContact CE1-CD1 3.3Å; F138-F240 HydrophobicContact CE1-CD1 3.3Å; F138-F240 AromaticContact CE1-CE1 3.96Å; F138-F240 HydrophobicContact CE1-CE1 3.96Å; F138-F240 AromaticContact CE1-CG 3.88Å; F138-F240 HydrophobicContact CE1-CG 3.88Å; F138-F244 HydrophobicContact CE1-CD1 4.21Å; F138-F244 AromaticContact CE1-CE1 3.63Å; F138-F244 HydrophobicContact CE1-CE1 3.63Å; F138-F244 HydrophobicContact CE1-CZ 4.1Å; F138-F244 HydrophobicContact CE2-CE1 4.42Å; F138-F244 AromaticContact CZ-CD1 3.66Å; F138-F244 HydrophobicContact CZ-CD1 3.66Å; F138-F244 AromaticContact CZ-CE1 3.48Å; F138-F244 HydrophobicContact CZ-CE1 3.48Å; F138-F244 VanDerWaalsContact CZ-CE1 3.48Å; F138-F244 HydrophobicContact CZ-CZ 4.36Å; F138-I247 HydrophobicContact CE2-CD1 3.95Å
139	A	87.6	Confident	88.4	Confident	23 Å²	23	16 Å²	16	19%	0.19	9%	0.09	C	C	.	.	H	α-helix	trans	-57.1	-32.7	-179.9	0	0	0	0	0	113.2	L135 I184	L135-A139 WeakPolarHBondContact O-CB 3.21Å; L135-A139 PolarHBondContact O-N 3.19Å; A139-I184 HydrophobicContact CB-CD1 3.99Å
140	A	83.6	Confident	88	Confident	15 Å²	15	14 Å²	14	12%	0.124	9%	0.089	C	C	.	.	H	α-helix	trans	-77.6	-35.7	175	0	0	0	0	0	113.5	A136 F137 F138 I201 V207	A136-A140 WeakPolarHBondContact O-CB 3.11Å; A136-A140 PolarHBondContact O-N 3.47Å; F137-A140 PolarHBondContact O-N 3.5Å; F138-A140 PolarHBondContact O-N 2.89Å; F138-A140 VanDerWaalsContact O-N 3.11Å; A140-I201 HydrophobicContact CB-CD1 3.96Å; A140-I201 HydrophobicContact CB-CG1 3.72Å; A140-V207 HydrophobicContact CB-CG1 4.44Å
141	S	83.7	Confident	87.3	Confident	11 Å²	11	18.7 Å²	18.7	8%	0.077	11%	0.111	C	C	.	.	H	α-helix	trans	-78	-41	-171.1	-59	0	0	0	0	112.5	F137 F138 G143 I144 V145	F137-S141 WeakPolarHBondContact CD2-OG 3.44Å; F137-S141 WeakPolarHBondContact CE2-OG 3.4Å; F137-S141 WeakPolarHBondContact CZ-OG 3.48Å; F137-S141 WeakPolarHBondContact O-CB 3.32Å; F137-S141 PolarHBondContact O-N 3.34Å; F137-S141 PolarHBondContact O-OG 3.47Å; F138-S141 PolarHBondContact O-N 3.3Å; S141-G143 PolarHBondContact O-N 3.37Å; S141-I144 WeakPolarHBondContact O-CA 3.33Å; S141-I144 WeakPolarHBondContact O-CB 3.45Å; S141-I144 PolarHBondContact O-N 3.21Å; S141-V145 PolarHBondContact O-N 2.91Å
142	D	82.4	Confident	86.7	Confident	3 Å²	3	19.5 Å²	19.5	2%	0.016	11%	0.113	C	C	.	.	H	α-helix	trans	-60.3	-34.3	178.8	-63.8	-0.9	0	0	0	111.3	F138 I144 V145 N146 H176 S177 Y180	F138-D142 PolarHBondContact O-N 3.13Å; F138-D142 VanDerWaalsContact O-N 3.11Å; D142-I144 VanDerWaalsContact C-N 3.32Å; D142-I144 PolarHBondContact O-N 2.98Å; D142-V145 PolarHBondContact O-N 3.41Å; D142-N146 VanDerWaalsContact O-CB 3.27Å; D142-N146 WeakPolarHBondContact O-CB 3.14Å; D142-N146 PolarHBondContact O-N 3.4Å; D142-H176 WeakPolarHBondContact OD2-CB 3.33Å; D142-S177 WeakPolarHBondContact CB-OG 3.39Å; D142-Y180 WeakPolarHBondContact OD2-CD2 3.47Å; D142-Y180 WeakPolarHBondContact OD2-CE2 3.37Å
143	G	84.2	Confident	86.5	Confident	33 Å²	33	19.4 Å²	19.4	34%	0.34	11%	0.113	S	C	.	.	H	α-helix	trans	-59.7	-40.7	172.6	0	0	0	0	0	113.1	S141 E147	S141-G143 PolarHBondContact O-N 3.37Å; G143-E147 WeakPolarHBondContact O-CG 3.38Å; G143-E147 PolarHBondContact O-N 2.85Å; G143-E147 VanDerWaalsContact O-N 3.15Å
144	I	83.5	Confident	86.3	Confident	13 Å²	13	20.1 Å²	20.1	7%	0.067	12%	0.118	C	C	.	.	H	α-helix	trans	-70.9	-42.1	178.4	-61.8	169.7	0	0	0	110.6	S141 D142 N146 E147 N148 I201 A211 A214 I215 I218	S141-I144 WeakPolarHBondContact O-CA 3.33Å; S141-I144 WeakPolarHBondContact O-CB 3.45Å; S141-I144 PolarHBondContact O-N 3.21Å; D142-I144 VanDerWaalsContact C-N 3.32Å; D142-I144 PolarHBondContact O-N 2.98Å; I144-N146 VanDerWaalsContact C-N 3.33Å; I144-N146 PolarHBondContact O-N 3.1Å; I144-E147 PolarHBondContact O-N 3.35Å; I144-N148 PolarHBondContact O-N 3.04Å; I144-N148 VanDerWaalsContact O-N 3.12Å; I144-I201 HydrophobicContact CD1-CD1 3.95Å; I144-I201 HydrophobicContact CG1-CD1 4.48Å; I144-A211 HydrophobicContact CD1-CB 3.61Å; I144-A214 HydrophobicContact CG2-CB 4.11Å; I144-I215 HydrophobicContact CD1-CD1 4.19Å; I144-I215 HydrophobicContact CD1-CG1 4.33Å; I144-I215 HydrophobicContact CG2-CG1 3.92Å; I144-I218 HydrophobicContact CG2-CD1 3.56Å; I144-I218 WeakPolarHBondContact O-CD1 3.32Å
145	V	83.4	Confident	86	Confident	6 Å²	6	26 Å²	26	4%	0.036	15%	0.145	C	C	.	.	H	α-helix	trans	-58.3	-47.1	175.8	169.3	0	0	0	0	110.4	S141 D142 E147 N148 L149 E173 F232 V235 E236	S141-V145 PolarHBondContact O-N 2.91Å; D142-V145 PolarHBondContact O-N 3.41Å; V145-E147 PolarHBondContact O-N 2.83Å; V145-N148 WeakPolarHBondContact O-CB 3.49Å; V145-N148 PolarHBondContact O-N 3.31Å; V145-N148 VanDerWaalsContact O-N 3.15Å; V145-L149 HydrophobicContact CG1-CD1 4.13Å; V145-L149 WeakPolarHBondContact O-CG 3.41Å; V145-L149 PolarHBondContact O-N 3.49Å; V145-E173 HydrophobicContact CG1-CG 4.31Å; V145-F232 HydrophobicContact CG1-CE2 3.97Å; V145-F232 HydrophobicContact CG1-CZ 4.22Å; V145-V235 HydrophobicContact CG2-CG1 3.78Å; V145-E236 WeakPolarHBondContact CG1-OE1 3.46Å
146	N	86.8	Confident	85.8	Confident	20 Å²	20	27.5 Å²	27.5	11%	0.107	15%	0.152	C	C	.	.	H	α-helix	trans	-63.9	-41.2	-179.4	-158.1	-19.4	0	0	0	112.1	D142 I144 N148 L149 V150 E173 N174	D142-N146 VanDerWaalsContact O-CB 3.27Å; D142-N146 WeakPolarHBondContact O-CB 3.14Å; D142-N146 PolarHBondContact O-N 3.4Å; I144-N146 VanDerWaalsContact C-N 3.33Å; I144-N146 PolarHBondContact O-N 3.1Å; N146-N148 VanDerWaalsContact C-N 3.33Å; N146-N148 PolarHBondContact O-N 3.4Å; N146-L149 PolarHBondContact O-N 3.26Å; N146-V150 WeakPolarHBondContact O-CG2 3.45Å; N146-V150 PolarHBondContact O-N 3.4Å; N146-E173 HydrophobicContact CB-CB 4.47Å; N146-N174 PolarHBondContact ND2-OD1 3.38Å
147	E	85.1	Confident	86	Confident	60 Å²	60	27.4 Å²	27.4	28%	0.28	15%	0.152	S	C	.	.	H	α-helix	trans	-58.5	-43	172.7	-76.5	-177.1	170.4	0	0	111.8	A53 F57 G143 I144 V145 L149 E151	A53-E147 WeakPolarHBondContact CB-OE1 3.47Å; F57-E147 WeakPolarHBondContact CE2-OE2 3.35Å; G143-E147 WeakPolarHBondContact O-CG 3.38Å; G143-E147 PolarHBondContact O-N 2.85Å; G143-E147 VanDerWaalsContact O-N 3.15Å; I144-E147 PolarHBondContact O-N 3.35Å; V145-E147 PolarHBondContact O-N 2.83Å; E147-L149 PolarHBondContact O-N 3.13Å; E147-E151 VanDerWaalsContact O-CB 3.31Å; E147-E151 WeakPolarHBondContact O-CB 3.36Å; E147-E151 WeakPolarHBondContact O-CG 3.5Å; E147-E151 PolarHBondContact O-N 3.17Å
148	N	85.2	Confident	86.2	Confident	10 Å²	10	29.1 Å²	29.1	5%	0.053	16%	0.16	C	C	.	.	H	α-helix	trans	-60.6	-46.4	175.2	-174.4	49.5	0	0	0	112.8	I144 V145 N146 R152 F153 I218 F232	I144-N148 PolarHBondContact O-N 3.04Å; I144-N148 VanDerWaalsContact O-N 3.12Å; V145-N148 WeakPolarHBondContact O-CB 3.49Å; V145-N148 PolarHBondContact O-N 3.31Å; V145-N148 VanDerWaalsContact O-N 3.15Å; N146-N148 VanDerWaalsContact C-N 3.33Å; N146-N148 PolarHBondContact O-N 3.4Å; N148-R152 WeakPolarHBondContact O-CA 3.25Å; N148-R152 WeakPolarHBondContact O-CB 3.14Å; N148-R152 PolarHBondContact O-N 2.78Å; N148-F153 PolarHBondContact O-N 3.18Å; N148-I218 HydrophobicContact CB-CD1 3.66Å; N148-I218 HydrophobicContact CB-CG1 3.68Å; N148-I218 HydrophobicContact CB-CG2 4.39Å; N148-F232 WeakPolarHBondContact ND2-CD2 3.39Å
149	L	85.6	Confident	86.3	Confident	0 Å²	0	29.4 Å²	29.4	0%	0	16%	0.162	C	C	.	.	I	π-helix	trans	-62.9	-46.2	-177.7	-73.4	172.7	0	0	0	111.6	V145 N146 E147 F153 T154 Y166 Q169 I170 E173 F232	V145-L149 HydrophobicContact CG1-CD1 4.13Å; V145-L149 WeakPolarHBondContact O-CG 3.41Å; V145-L149 PolarHBondContact O-N 3.49Å; N146-L149 PolarHBondContact O-N 3.26Å; E147-L149 PolarHBondContact O-N 3.13Å; L149-F153 HydrophobicContact CD2-CD2 4.11Å; L149-T154 VanDerWaalsContact O-CB 3.32Å; L149-T154 WeakPolarHBondContact O-CB 3.28Å; L149-T154 PolarHBondContact O-N 3.34Å; L149-T154 PolarHBondContact O-OG1 3.27Å; L149-Y166 HydrophobicContact CD2-CD1 3.68Å; L149-Y166 HydrophobicContact CD2-CE1 3.95Å; L149-Q169 HydrophobicContact CD1-CG 3.7Å; L149-I170 HydrophobicContact CB-CD1 4.13Å; L149-I170 HydrophobicContact CB-CG1 3.77Å; L149-I170 HydrophobicContact CD1-CG1 4.07Å; L149-E173 HydrophobicContact CD1-CG 4.04Å; L149-F232 HydrophobicContact CD1-CZ 4.35Å; L149-F232 HydrophobicContact CD2-CE1 4.26Å; L149-F232 HydrophobicContact CD2-CE2 4.1Å; L149-F232 HydrophobicContact CD2-CZ 3.58Å; L149-F232 HydrophobicContact CG-CE2 4.21Å; L149-F232 HydrophobicContact CG-CZ 4Å
150	V	85.7	Confident	86.6	Confident	67 Å²	67	29.6 Å²	29.6	41%	0.406	16%	0.16	S	C	.	.	I	π-helix	trans	-72.3	-49.4	-176.8	173.5	0	0	0	0	111.5	N146 I170	N146-V150 WeakPolarHBondContact O-CG2 3.45Å; N146-V150 PolarHBondContact O-N 3.4Å; V150-I170 HydrophobicContact CG2-CD1 3.82Å; V150-I170 HydrophobicContact CG2-CG1 4.17Å; V150-I170 HydrophobicContact CG2-CG2 4.25Å
151	E	81.1	Confident	87.2	Confident	101 Å²	101	28.9 Å²	28.9	47%	0.472	15%	0.154	S	C	.	.	I	π-helix	trans	-79.7	-27.6	-172.3	-63.9	-164.8	162.6	0	0	112.9	E147	E147-E151 VanDerWaalsContact O-CB 3.31Å; E147-E151 WeakPolarHBondContact O-CB 3.36Å; E147-E151 WeakPolarHBondContact O-CG 3.5Å; E147-E151 PolarHBondContact O-N 3.17Å
152	R	84.1	Confident	87.8	Confident	22 Å²	22	28.3 Å²	28.3	8%	0.083	15%	0.151	C	C	.	.	I	π-helix	trans	-117.9	-73	-173.5	-58.5	-138.2	64.9	169.9	-0.4	113.5	N148 T154 Q155 E156 I218	N148-R152 WeakPolarHBondContact O-CA 3.25Å; N148-R152 WeakPolarHBondContact O-CB 3.14Å; N148-R152 PolarHBondContact O-N 2.78Å; R152-T154 VanDerWaalsContact C-N 3.35Å; R152-T154 PolarHBondContact O-N 3.18Å; R152-Q155 PolarHBondContact O-N 2.99Å; R152-E156 IonicContact CZ-OE1 3.75Å; R152-E156 IonicContact NE-OE1 2.74Å; R152-E156 PolarHBondContact NE-OE1 3.44Å; R152-E156 IonicContact NH2-OE1 3.06Å; R152-E156 PolarHBondContact NH2-OE1 2.82Å; R152-E156 WeakPolarHBondContact O-CB 3.49Å; R152-E156 WeakPolarHBondContact O-CG 3.47Å; R152-E156 PolarHBondContact O-N 3.37Å; R152-I218 WeakPolarHBondContact CD-O 3.49Å; R152-I218 HydrophobicContact CG-CG2 4.41Å; R152-I218 PolarHBondContact NH1-O 3.28Å; R152-I218 VanDerWaalsContact NH1-O 3.15Å
153	F	88.7	Confident	88.3	Confident	1 Å²	1	32.6 Å²	32.6	0%	0.004	17%	0.167	C	C	.	.	I	π-helix	trans	-62.4	-40.3	-166.1	-72.4	-8.1	0	0	0	113.4	N148 L149 Q155 E156 V157 Y166 Y225 R228 V229 F232	N148-F153 PolarHBondContact O-N 3.18Å; L149-F153 HydrophobicContact CD2-CD2 4.11Å; F153-Q155 VanDerWaalsContact C-N 3.28Å; F153-Q155 PolarHBondContact O-N 3.26Å; F153-E156 PolarHBondContact O-N 3.45Å; F153-V157 WeakPolarHBondContact O-CB 3.43Å; F153-V157 WeakPolarHBondContact O-CG2 3.32Å; F153-V157 PolarHBondContact O-N 3.33Å; F153-Y166 HydrophobicContact CB-CE1 4.42Å; F153-Y166 HydrophobicContact CB-CE2 4.09Å; F153-Y166 HydrophobicContact CD2-CE1 4.24Å; F153-Y225 HydrophobicContact CD1-CD2 4.49Å; F153-Y225 HydrophobicContact CD1-CE2 4.02Å; F153-Y225 HydrophobicContact CE1-CD2 4.45Å; F153-Y225 HydrophobicContact CE1-CE2 4.2Å; F153-R228 HydrophobicContact CE1-CB 3.98Å; F153-R228 HydrophobicContact CZ-CB 4.22Å; F153-V229 HydrophobicContact CZ-CG2 4.42Å; F153-F232 HydrophobicContact CD2-CD1 4.39Å; F153-F232 HydrophobicContact CD2-CG 4.36Å; F153-F232 HydrophobicContact CE2-CB 3.61Å; F153-F232 AromaticContact CE2-CD1 3.66Å; F153-F232 HydrophobicContact CE2-CD1 3.66Å; F153-F232 AromaticContact CE2-CD2 3.78Å; F153-F232 HydrophobicContact CE2-CD2 3.78Å; F153-F232 HydrophobicContact CE2-CE1 4.23Å; F153-F232 HydrophobicContact CE2-CE2 4.32Å; F153-F232 AromaticContact CE2-CG 3.4Å; F153-F232 HydrophobicContact CE2-CG 3.4Å; F153-F232 VanDerWaalsContact CE2-CG 3.4Å; F153-F232 HydrophobicContact CZ-CB 3.8Å; F153-F232 HydrophobicContact CZ-CD2 4.49Å; F153-F232 HydrophobicContact CZ-CG 4.1Å
154	T	87.7	Confident	88.9	Confident	30 Å²	30	32.8 Å²	32.8	18%	0.184	16%	0.163	C	C	.	.	H	α-helix	trans	-68.3	-29.8	177.9	-49.2	0	0	0	0	112.4	L149 R152 R163	L149-T154 VanDerWaalsContact O-CB 3.32Å; L149-T154 WeakPolarHBondContact O-CB 3.28Å; L149-T154 PolarHBondContact O-N 3.34Å; L149-T154 PolarHBondContact O-OG1 3.27Å; R152-T154 VanDerWaalsContact C-N 3.35Å; R152-T154 PolarHBondContact O-N 3.18Å; T154-R163 PolarHBondContact O-NE 3.03Å
155	Q	86.5	Confident	89.5	Confident	125 Å²	125	32.2 Å²	32.2	58%	0.584	16%	0.16	S	C	*	.	H	α-helix	trans	-80.3	-38.6	178.4	-58.3	-57.1	-37	0	0	112.4	R152 F153 Q158	R152-Q155 PolarHBondContact O-N 2.99Å; F153-Q155 VanDerWaalsContact C-N 3.28Å; F153-Q155 PolarHBondContact O-N 3.26Å; Q155-Q158 PolarHBondContact O-NE2 2.83Å
156	E	90.2	Very high	90.2	Very high	35 Å²	35	32 Å²	32	16%	0.164	16%	0.158	C	C	.	.	H	α-helix	trans	-76.2	-46.7	-176.8	-73.9	173.8	-155.6	0	0	112.1	L77 R152 F153 Q158 Y225 R228	L77-E156 HydrophobicContact CD2-CB 4.33Å; R152-E156 IonicContact CZ-OE1 3.75Å; R152-E156 IonicContact NE-OE1 2.74Å; R152-E156 PolarHBondContact NE-OE1 3.44Å; R152-E156 IonicContact NH2-OE1 3.06Å; R152-E156 PolarHBondContact NH2-OE1 2.82Å; R152-E156 WeakPolarHBondContact O-CB 3.49Å; R152-E156 WeakPolarHBondContact O-CG 3.47Å; R152-E156 PolarHBondContact O-N 3.37Å; F153-E156 PolarHBondContact O-N 3.45Å; E156-Q158 PolarHBondContact O-N 2.76Å; E156-Q158 PolarHBondContact O-NE2 3.03Å; E156-Y225 WeakPolarHBondContact OE2-CD2 3.48Å; E156-R228 IonicContact OE1-CZ 3.62Å; E156-R228 IonicContact OE1-NH2 2.76Å; E156-R228 IonicContact OE2-CZ 3.36Å; E156-R228 IonicContact OE2-NE 3.53Å; E156-R228 IonicContact OE2-NH2 3.96Å; E156-R228 PolarHBondContact OE2-NH2 3.42Å
157	V	92.8	Very high	90.7	Very high	0 Å²	0	33 Å²	33	0%	0	17%	0.172	C	C	.	.			trans	-72.9	127.3	-178	178.4	0	0	0	0	110	L76 L77 F153 V159 A162 R163 Y166 Y225 M280	L76-V157 WeakPolarHBondContact O-CA 3.49Å; L77-V157 HydrophobicContact CD2-CG2 4.35Å; F153-V157 WeakPolarHBondContact O-CB 3.43Å; F153-V157 WeakPolarHBondContact O-CG2 3.32Å; F153-V157 PolarHBondContact O-N 3.33Å; V157-V159 HydrophobicContact CG1-CB 4.25Å; V157-A162 HydrophobicContact CG1-CB 3.69Å; V157-R163 VanDerWaalsContact O-CZ 3.26Å; V157-R163 PolarHBondContact O-NE 2.98Å; V157-R163 PolarHBondContact O-NH2 2.9Å; V157-Y166 HydrophobicContact CB-CE2 4.36Å; V157-Y166 HydrophobicContact CG2-CE2 4.03Å; V157-Y225 HydrophobicContact CG2-CE2 3.82Å; V157-Y225 VanDerWaalsContact CG2-OH 3.28Å; V157-Y225 WeakPolarHBondContact CG2-OH 3.47Å; V157-M280 HydrophobicContact CG1-CE 4.07Å; V157-M280 HydrophobicContact CG2-CE 4.25Å
158	Q	91.8	Very high	91.2	Very high	37 Å²	37	31.6 Å²	31.6	17%	0.173	17%	0.166	C	C	.	.			trans	-102.5	-9.2	-177.1	-56.6	-55.9	-54.4	0	0	113.1	L76 L77 K78 Q155 E156 T160 R163	L76-Q158 PolarHBondContact O-N 3.21Å; L77-Q158 WeakPolarHBondContact O-CG 3.46Å; K78-Q158 WeakPolarHBondContact O-CB 3.42Å; K78-Q158 VanDerWaalsContact O-CG 3.32Å; K78-Q158 WeakPolarHBondContact O-CG 3.44Å; Q155-Q158 PolarHBondContact O-NE2 2.83Å; E156-Q158 PolarHBondContact O-N 2.76Å; E156-Q158 PolarHBondContact O-NE2 3.03Å; Q158-T160 PolarHBondContact O-N 2.86Å; Q158-R163 VanDerWaalsContact NE2-NH2 3.11Å
159	V	92.9	Very high	91.8	Very high	6 Å²	6	31.2 Å²	31.2	4%	0.036	16%	0.164	C	C	.	.			trans	-74.1	120.4	177.4	175.8	0	0	0	0	110.1	L76 Y91 I94 V157 E161 A162 R163	L76-V159 HydrophobicContact CD2-CG2 3.92Å; Y91-V159 HydrophobicContact CD2-CG1 3.49Å; Y91-V159 VanDerWaalsContact CD2-CG1 3.49Å; Y91-V159 HydrophobicContact CD2-CG2 4.35Å; Y91-V159 HydrophobicContact CE2-CG1 3.87Å; Y91-V159 HydrophobicContact CE2-CG2 3.86Å; Y91-V159 HydrophobicContact CG-CG1 4.14Å; I94-V159 HydrophobicContact CD1-CG1 4.36Å; V157-V159 HydrophobicContact CG1-CB 4.25Å; V159-E161 HydrophobicContact CG1-CB 4.36Å; V159-E161 VanDerWaalsContact CG1-OE2 3.32Å; V159-E161 WeakPolarHBondContact CG1-OE2 3.39Å; V159-E161 PolarHBondContact O-N 2.91Å; V159-A162 HydrophobicContact CB-CB 4.2Å; V159-A162 HydrophobicContact CG1-CB 4.29Å; V159-A162 PolarHBondContact O-N 3.49Å; V159-R163 PolarHBondContact O-N 3.29Å
160	T	93.3	Very high	92.3	Very high	26 Å²	26	32.6 Å²	32.6	16%	0.16	17%	0.171	C	C	.	.	H	α-helix	trans	-60.9	-42.2	-175	-44.9	0	0	0	0	112.4	R83 I86 Q158 A162 R163 C164	R83-T160 WeakPolarHBondContact CD-OG1 3.49Å; R83-T160 WeakPolarHBondContact CG-OG1 3.45Å; I86-T160 HydrophobicContact CD1-CG2 3.7Å; Q158-T160 PolarHBondContact O-N 2.86Å; T160-A162 VanDerWaalsContact C-N 3.28Å; T160-A162 PolarHBondContact O-N 2.85Å; T160-R163 WeakPolarHBondContact O-CB 3.5Å; T160-R163 PolarHBondContact O-N 2.97Å; T160-C164 PolarHBondContact O-N 3.3Å; T160-C164 PolarHBondContact O-SG 2.95Å; T160-C164 VanDerWaalsContact O-SG 3.4Å
161	E	95.8	Very high	92.9	Very high	0 Å²	0	31.5 Å²	31.5	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-60.6	-39.1	178.1	-62.2	91.9	149.3	0	0	112	R83 I86 I89 Q90 Y91 I94 W95 V159 C164 F165	R83-E161 IonicContact CZ-OE1 3.67Å; R83-E161 IonicContact CZ-OE2 2.67Å; R83-E161 VanDerWaalsContact CZ-OE2 3.27Å; R83-E161 IonicContact NH1-OE1 2.76Å; R83-E161 PolarHBondContact NH1-OE1 2.99Å; R83-E161 IonicContact NH1-OE2 3.82Å; R83-E161 PolarHBondContact NH1-OE2 3.5Å; R83-E161 IonicContact NH2-OE1 2.99Å; R83-E161 PolarHBondContact NH2-OE1 3.06Å; R83-E161 IonicContact NH2-OE2 3.53Å; R83-E161 PolarHBondContact NH2-OE2 2.75Å; I86-E161 HydrophobicContact CD1-CG 4.24Å; I89-E161 HydrophobicContact CD1-CG 4.41Å; I89-E161 HydrophobicContact CG2-CG 4.3Å; Q90-E161 PolarHBondContact N-OE1 3.23Å; Y91-E161 PolarHBondContact N-OE1 3.45Å; I94-E161 HydrophobicContact CB-CB 4.12Å; I94-E161 HydrophobicContact CG2-CB 3.63Å; W95-E161 HydrophobicContact CB-CG 4.16Å; W95-E161 HydrophobicContact CE3-CB 4.23Å; W95-E161 HydrophobicContact CE3-CG 4.03Å; V159-E161 HydrophobicContact CG1-CB 4.36Å; V159-E161 VanDerWaalsContact CG1-OE2 3.32Å; V159-E161 WeakPolarHBondContact CG1-OE2 3.39Å; V159-E161 PolarHBondContact O-N 2.91Å; E161-C164 WeakPolarHBondContact O-CB 3.43Å; E161-C164 PolarHBondContact O-N 3.23Å; E161-F165 PolarHBondContact O-N 2.95Å; E161-F165 VanDerWaalsContact O-N 3.15Å
162	A	96.1	Very high	93.6	Very high	0 Å²	0	26.8 Å²	26.8	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-71.3	-36.5	178.2	0	0	0	0	0	111.5	I94 V157 V159 T160 C164 F165 Y166 F276 M280	I94-A162 HydrophobicContact CG2-CB 3.93Å; V157-A162 HydrophobicContact CG1-CB 3.69Å; V159-A162 HydrophobicContact CB-CB 4.2Å; V159-A162 HydrophobicContact CG1-CB 4.29Å; V159-A162 PolarHBondContact O-N 3.49Å; T160-A162 VanDerWaalsContact C-N 3.28Å; T160-A162 PolarHBondContact O-N 2.85Å; A162-C164 VanDerWaalsContact C-N 3.3Å; A162-C164 PolarHBondContact O-N 2.98Å; A162-F165 WeakPolarHBondContact O-CB 3.41Å; A162-F165 PolarHBondContact O-N 3.32Å; A162-Y166 WeakPolarHBondContact O-CD2 3.43Å; A162-Y166 PolarHBondContact O-N 3.18Å; A162-F276 HydrophobicContact CB-CZ 4.04Å; A162-M280 HydrophobicContact CB-CE 3.97Å; A162-M280 HydrophobicContact CB-SD 4Å
163	R	94.3	Very high	94.2	Very high	92 Å²	92	25.8 Å²	25.8	35%	0.347	14%	0.142	S	C	.	.	H	α-helix	trans	-62.9	-35.6	171.4	-71.8	-174.2	173.9	170.1	4.6	112.6	T154 V157 Q158 V159 T160 G167	T154-R163 PolarHBondContact O-NE 3.03Å; V157-R163 VanDerWaalsContact O-CZ 3.26Å; V157-R163 PolarHBondContact O-NE 2.98Å; V157-R163 PolarHBondContact O-NH2 2.9Å; Q158-R163 VanDerWaalsContact NE2-NH2 3.11Å; V159-R163 PolarHBondContact O-N 3.29Å; T160-R163 WeakPolarHBondContact O-CB 3.5Å; T160-R163 PolarHBondContact O-N 2.97Å; R163-G167 PolarHBondContact O-N 3.01Å
164	C	95.7	Very high	94.5	Very high	38 Å²	38	29.8 Å²	29.8	26%	0.257	16%	0.164	S	C	.	.	H	α-helix	trans	-63.4	-43.9	173	-68	0	0	0	0	111.4	W95 Y98 T160 E161 A162 G167 F168	W95-C164 HydrophobicContact CZ3-CB 3.91Å; Y98-C164 HydrophobicContact CD1-CB 4.4Å; Y98-C164 HydrophobicContact CD2-CB 3.86Å; Y98-C164 WeakPolarHBondContact CD2-O 3.34Å; Y98-C164 HydrophobicContact CE2-CB 4.04Å; Y98-C164 HydrophobicContact CG-CB 4.05Å; T160-C164 PolarHBondContact O-N 3.3Å; T160-C164 PolarHBondContact O-SG 2.95Å; T160-C164 VanDerWaalsContact O-SG 3.4Å; E161-C164 WeakPolarHBondContact O-CB 3.43Å; E161-C164 PolarHBondContact O-N 3.23Å; A162-C164 VanDerWaalsContact C-N 3.3Å; A162-C164 PolarHBondContact O-N 2.98Å; C164-G167 PolarHBondContact O-N 3.21Å; C164-F168 PolarHBondContact O-N 3.02Å; C164-F168 VanDerWaalsContact O-N 3.14Å
165	F	97.7	Very high	95	Very high	1 Å²	1	29.3 Å²	29.3	0%	0.004	16%	0.16	C	C	.	.	H	α-helix	trans	-59.2	-54.2	173.9	-171.3	-79.8	0	0	0	111.5	M97 A101 E161 A162 G167 F168 Q169 L272 F276	M97-F165 HydrophobicContact CB-CD2 3.93Å; M97-F165 HydrophobicContact CB-CE2 3.9Å; A101-F165 HydrophobicContact CB-CD2 4.4Å; A101-F165 HydrophobicContact CB-CE2 3.97Å; E161-F165 PolarHBondContact O-N 2.95Å; E161-F165 VanDerWaalsContact O-N 3.15Å; A162-F165 WeakPolarHBondContact O-CB 3.41Å; A162-F165 PolarHBondContact O-N 3.32Å; F165-G167 VanDerWaalsContact C-N 3.31Å; F165-G167 PolarHBondContact O-N 2.86Å; F165-F168 PolarHBondContact O-N 3.45Å; F165-Q169 HydrophobicContact CD1-CB 4.45Å; F165-Q169 HydrophobicContact CE1-CB 4.29Å; F165-Q169 PolarHBondContact O-N 2.94Å; F165-L272 HydrophobicContact CE2-CD2 4.5Å; F165-L272 HydrophobicContact CE2-CG 4.26Å; F165-L272 HydrophobicContact CZ-CG 4.18Å; F165-F276 HydrophobicContact CB-CD2 4.28Å; F165-F276 HydrophobicContact CB-CE1 4.02Å; F165-F276 HydrophobicContact CB-CE2 3.65Å; F165-F276 HydrophobicContact CB-CZ 3.51Å; F165-F276 HydrophobicContact CD1-CB 4.17Å; F165-F276 AromaticContact CD1-CD1 3.26Å; F165-F276 HydrophobicContact CD1-CD1 3.26Å; F165-F276 AromaticContact CD1-CD2 3.77Å; F165-F276 HydrophobicContact CD1-CD2 3.77Å; F165-F276 AromaticContact CD1-CE1 3.43Å; F165-F276 HydrophobicContact CD1-CE1 3.43Å; F165-F276 VanDerWaalsContact CD1-CE1 3.43Å; F165-F276 AromaticContact CD1-CE2 3.91Å; F165-F276 HydrophobicContact CD1-CE2 3.91Å; F165-F276 AromaticContact CD1-CG 3.44Å; F165-F276 HydrophobicContact CD1-CG 3.44Å; F165-F276 VanDerWaalsContact CD1-CG 3.44Å; F165-F276 AromaticContact CD1-CZ 3.76Å; F165-F276 HydrophobicContact CD1-CZ 3.76Å; F165-F276 AromaticContact CD2-CD2 3.52Å; F165-F276 HydrophobicContact CD2-CD2 3.52Å; F165-F276 AromaticContact CD2-CE2 3.71Å; F165-F276 HydrophobicContact CD2-CE2 3.71Å; F165-F276 AromaticContact CD2-CG 3.97Å; F165-F276 HydrophobicContact CD2-CG 3.97Å; F165-F276 HydrophobicContact CD2-CZ 4.32Å; F165-F276 HydrophobicContact CE1-CB 3.52Å; F165-F276 AromaticContact CE1-CD1 3.42Å; F165-F276 HydrophobicContact CE1-CD1 3.42Å; F165-F276 VanDerWaalsContact CE1-CD1 3.42Å; F165-F276 AromaticContact CE1-CD2 3.94Å; F165-F276 HydrophobicContact CE1-CD2 3.94Å; F165-F276 HydrophobicContact CE1-CE1 4.09Å; F165-F276 AromaticContact CE1-CG 3.33Å; F165-F276 HydrophobicContact CE1-CG 3.33Å; F165-F276 HydrophobicContact CE2-CB 3.98Å; F165-F276 AromaticContact CE2-CD2 3.71Å; F165-F276 HydrophobicContact CE2-CD2 3.71Å; F165-F276 HydrophobicContact CE2-CE2 4.37Å; F165-F276 AromaticContact CE2-CG 3.87Å; F165-F276 HydrophobicContact CE2-CG 3.87Å; F165-F276 AromaticContact CG-CD1 3.89Å; F165-F276 HydrophobicContact CG-CD1 3.89Å; F165-F276 AromaticContact CG-CD2 3.57Å; F165-F276 HydrophobicContact CG-CD2 3.57Å; F165-F276 AromaticContact CG-CE1 3.8Å; F165-F276 HydrophobicContact CG-CE1 3.8Å; F165-F276 AromaticContact CG-CE2 3.46Å; F165-F276 HydrophobicContact CG-CE2 3.46Å; F165-F276 VanDerWaalsContact CG-CE2 3.46Å; F165-F276 AromaticContact CG-CG 3.78Å; F165-F276 HydrophobicContact CG-CG 3.78Å; F165-F276 AromaticContact CG-CZ 3.59Å; F165-F276 HydrophobicContact CG-CZ 3.59Å; F165-F276 HydrophobicContact CZ-CB 3.41Å; F165-F276 VanDerWaalsContact CZ-CB 3.41Å; F165-F276 HydrophobicContact CZ-CD1 4.15Å; F165-F276 AromaticContact CZ-CD2 3.92Å; F165-F276 HydrophobicContact CZ-CD2 3.92Å; F165-F276 AromaticContact CZ-CG 3.56Å; F165-F276 HydrophobicContact CZ-CG 3.56Å
166	Y	97.1	Very high	95.5	Very high	2 Å²	2	23.4 Å²	23.4	1%	0.008	13%	0.132	C	C	.	.	H	α-helix	trans	-61.9	-36.9	-179.1	-71.1	-48.1	0	0	0	113.1	L149 F153 V157 A162 F168 Q169 I170 F276	L149-Y166 HydrophobicContact CD2-CD1 3.68Å; L149-Y166 HydrophobicContact CD2-CE1 3.95Å; F153-Y166 HydrophobicContact CB-CE1 4.42Å; F153-Y166 HydrophobicContact CB-CE2 4.09Å; F153-Y166 HydrophobicContact CD2-CE1 4.24Å; V157-Y166 HydrophobicContact CB-CE2 4.36Å; V157-Y166 HydrophobicContact CG2-CE2 4.03Å; A162-Y166 WeakPolarHBondContact O-CD2 3.43Å; A162-Y166 PolarHBondContact O-N 3.18Å; Y166-F168 VanDerWaalsContact C-N 3.27Å; Y166-F168 PolarHBondContact O-N 2.92Å; Y166-Q169 PolarHBondContact O-N 2.94Å; Y166-I170 WeakPolarHBondContact O-CB 3.47Å; Y166-I170 WeakPolarHBondContact O-CD1 3.19Å; Y166-I170 VanDerWaalsContact O-CG1 3.24Å; Y166-I170 WeakPolarHBondContact O-CG1 3.47Å; Y166-I170 PolarHBondContact O-N 3.48Å; Y166-F276 HydrophobicContact CD1-CE1 4.12Å; Y166-F276 AromaticContact CE1-CD1 3.95Å; Y166-F276 HydrophobicContact CE1-CD1 3.95Å; Y166-F276 AromaticContact CE1-CE1 3.65Å; Y166-F276 HydrophobicContact CE1-CE1 3.65Å; Y166-F276 HydrophobicContact CE2-CE1 4.12Å; Y166-F276 AromaticContact CZ-CE1 3.66Å
167	G	96.4	Very high	95.7	Very high	39 Å²	39	23 Å²	23	40%	0.402	13%	0.133	S	C	.	.	H	α-helix	trans	-61.3	-37.7	174.5	0	0	0	0	0	112.6	R163 C164 F165 A171	R163-G167 PolarHBondContact O-N 3.01Å; C164-G167 PolarHBondContact O-N 3.21Å; F165-G167 VanDerWaalsContact C-N 3.31Å; F165-G167 PolarHBondContact O-N 2.86Å; G167-A171 PolarHBondContact O-N 2.69Å
168	F	97.2	Very high	95.8	Very high	32 Å²	32	27.7 Å²	27.7	14%	0.14	16%	0.155	C	C	.	.	H	α-helix	trans	-74.4	-41	175	-166	-90.7	0	0	0	112.1	Y98 A101 E102 F105 C164 F165 Y166 I170 A171 M172	Y98-F168 HydrophobicContact CD2-CB 4.34Å; Y98-F168 HydrophobicContact CE2-CB 4.14Å; A101-F168 HydrophobicContact CB-CD1 3.69Å; A101-F168 HydrophobicContact CB-CE1 4.05Å; A101-F168 WeakPolarHBondContact O-CE1 3.04Å; E102-F168 HydrophobicContact CB-CE2 4.47Å; F105-F168 HydrophobicContact CB-CZ 3.86Å; F105-F168 HydrophobicContact CD2-CE2 4.15Å; F105-F168 AromaticContact CD2-CZ 3.86Å; F105-F168 HydrophobicContact CD2-CZ 3.86Å; F105-F168 HydrophobicContact CG-CZ 4.34Å; C164-F168 PolarHBondContact O-N 3.02Å; C164-F168 VanDerWaalsContact O-N 3.14Å; F165-F168 PolarHBondContact O-N 3.45Å; Y166-F168 VanDerWaalsContact C-N 3.27Å; Y166-F168 PolarHBondContact O-N 2.92Å; F168-I170 PolarHBondContact O-N 3.33Å; F168-A171 WeakPolarHBondContact O-CB 3.38Å; F168-A171 PolarHBondContact O-N 3.33Å; F168-A171 VanDerWaalsContact O-N 3.11Å; F168-M172 HydrophobicContact CD1-CG 3.89Å; F168-M172 HydrophobicContact CE1-CG 3.52Å; F168-M172 HydrophobicContact CE1-SD 3.9Å; F168-M172 HydrophobicContact CZ-CG 4.22Å; F168-M172 HydrophobicContact CZ-SD 4.03Å; F168-M172 PolarHBondContact O-N 3.47Å
169	Q	97.5	Very high	96.1	Very high	2 Å²	2	25.9 Å²	25.9	1%	0.009	15%	0.147	C	C	.	.	H	α-helix	trans	-55.1	-51.3	173.3	179.3	170.6	6.3	0	0	110.5	L149 F165 Y166 A171 M172 E173 E236 H273	L149-Q169 HydrophobicContact CD1-CG 3.7Å; F165-Q169 HydrophobicContact CD1-CB 4.45Å; F165-Q169 HydrophobicContact CE1-CB 4.29Å; F165-Q169 PolarHBondContact O-N 2.94Å; Y166-Q169 PolarHBondContact O-N 2.94Å; Q169-A171 PolarHBondContact O-N 2.91Å; Q169-M172 CarbonylContact O-C 3.49Å; Q169-M172 WeakPolarHBondContact O-CA 3.26Å; Q169-M172 PolarHBondContact O-N 2.97Å; Q169-E173 HydrophobicContact CG-CG 4.27Å; Q169-E173 WeakPolarHBondContact O-CG 2.94Å; Q169-E173 PolarHBondContact O-N 2.74Å; Q169-E236 PolarHBondContact NE2-OE1 2.92Å; Q169-H273 VanDerWaalsContact NE2-CG 3.31Å; Q169-H273 PolarHBondContact NE2-ND1 2.94Å
170	I	96.5	Very high	96.3	Very high	29 Å²	29	25.9 Å²	25.9	15%	0.149	15%	0.146	C	C	.	.	H	α-helix	trans	-54.3	-40.1	176.4	-70.9	160.2	0	0	0	111.9	L149 V150 Y166 F168 N174	L149-I170 HydrophobicContact CB-CD1 4.13Å; L149-I170 HydrophobicContact CB-CG1 3.77Å; L149-I170 HydrophobicContact CD1-CG1 4.07Å; V150-I170 HydrophobicContact CG2-CD1 3.82Å; V150-I170 HydrophobicContact CG2-CG1 4.17Å; V150-I170 HydrophobicContact CG2-CG2 4.25Å; Y166-I170 WeakPolarHBondContact O-CB 3.47Å; Y166-I170 WeakPolarHBondContact O-CD1 3.19Å; Y166-I170 VanDerWaalsContact O-CG1 3.24Å; Y166-I170 WeakPolarHBondContact O-CG1 3.47Å; Y166-I170 PolarHBondContact O-N 3.48Å; F168-I170 PolarHBondContact O-N 3.33Å; I170-N174 PolarHBondContact O-N 2.57Å; I170-N174 PolarHBondContact O-ND2 2.93Å
171	A	96.9	Very high	96.2	Very high	43 Å²	43	26.9 Å²	26.9	36%	0.355	16%	0.155	S	C	.	.	H	α-helix	trans	-64.9	-42.6	176.6	0	0	0	0	0	111.6	G167 F168 Q169 N174 I175	G167-A171 PolarHBondContact O-N 2.69Å; F168-A171 WeakPolarHBondContact O-CB 3.38Å; F168-A171 PolarHBondContact O-N 3.33Å; F168-A171 VanDerWaalsContact O-N 3.11Å; Q169-A171 PolarHBondContact O-N 2.91Å; A171-N174 WeakPolarHBondContact O-CB 3.44Å; A171-N174 PolarHBondContact O-N 3.12Å; A171-I175 PolarHBondContact O-N 3.09Å
172	M	97	Very high	96.2	Very high	3 Å²	3	30.1 Å²	30.1	2%	0.015	17%	0.171	C	C	.	.	H	α-helix	trans	-67.9	-40.3	177	-66	-50.4	-51.1	0	0	112.8	F105 W106 F168 Q169 N174 I175 H176	F105-M172 HydrophobicContact CD2-SD 3.93Å; F105-M172 HydrophobicContact CE2-SD 4.42Å; W106-M172 HydrophobicContact CD2-CE 4.33Å; W106-M172 HydrophobicContact CG-CE 4.09Å; F168-M172 HydrophobicContact CD1-CG 3.89Å; F168-M172 HydrophobicContact CE1-CG 3.52Å; F168-M172 HydrophobicContact CE1-SD 3.9Å; F168-M172 HydrophobicContact CZ-CG 4.22Å; F168-M172 HydrophobicContact CZ-SD 4.03Å; F168-M172 PolarHBondContact O-N 3.47Å; Q169-M172 CarbonylContact O-C 3.49Å; Q169-M172 WeakPolarHBondContact O-CA 3.26Å; Q169-M172 PolarHBondContact O-N 2.97Å; M172-N174 PolarHBondContact O-N 2.92Å; M172-I175 HydrophobicContact CE-CB 4.4Å; M172-I175 HydrophobicContact CE-CD1 4.07Å; M172-I175 HydrophobicContact CE-CG2 4.38Å; M172-I175 CarbonylContact O-C 3.55Å; M172-I175 WeakPolarHBondContact O-CA 3.42Å; M172-I175 WeakPolarHBondContact O-CB 3.36Å; M172-I175 PolarHBondContact O-N 3.04Å; M172-I175 HydrophobicContact SD-CD1 3.83Å; M172-H176 PolarHBondContact O-CD2 3.42Å; M172-H176 PolarHBondContact O-N 2.9Å
173	E	95.7	Very high	96.3	Very high	0 Å²	0	30.1 Å²	30.1	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-57	-35.2	174.2	-66.1	-53.2	145	0	0	112.3	V145 N146 L149 Q169 H176 S177 H273	V145-E173 HydrophobicContact CG1-CG 4.31Å; N146-E173 HydrophobicContact CB-CB 4.47Å; L149-E173 HydrophobicContact CD1-CG 4.04Å; Q169-E173 HydrophobicContact CG-CG 4.27Å; Q169-E173 WeakPolarHBondContact O-CG 2.94Å; Q169-E173 PolarHBondContact O-N 2.74Å; E173-H176 PolarHBondContact O-N 3.4Å; E173-S177 WeakPolarHBondContact O-CB 3.28Å; E173-S177 PolarHBondContact O-N 2.79Å; E173-S177 PolarHBondContact O-OG 3.23Å; E173-H273 IonicContact OE1-CE1 2.61Å; E173-H273 PolarHBondContact OE1-CE1 3.14Å; E173-H273 IonicContact OE1-ND1 2.74Å; E173-H273 PolarHBondContact OE1-ND1 3.46Å
174	N	96.1	Very high	96.3	Very high	86 Å²	86	25.8 Å²	25.8	46%	0.46	16%	0.155	S	C	.	.	H	α-helix	trans	-68.2	-38.6	174.8	-69.8	-49	0	0	0	111.9	N146 I170 A171 M172 S177 E178	N146-N174 PolarHBondContact ND2-OD1 3.38Å; I170-N174 PolarHBondContact O-N 2.57Å; I170-N174 PolarHBondContact O-ND2 2.93Å; A171-N174 WeakPolarHBondContact O-CB 3.44Å; A171-N174 PolarHBondContact O-N 3.12Å; M172-N174 PolarHBondContact O-N 2.92Å; N174-S177 PolarHBondContact O-N 3.35Å; N174-E178 WeakPolarHBondContact O-CB 3.49Å; N174-E178 PolarHBondContact O-N 2.89Å
175	I	97.3	Very high	96.1	Very high	20 Å²	20	27.8 Å²	27.8	10%	0.103	16%	0.163	C	C	.	.	H	α-helix	trans	-68.7	-38.8	176	-68.5	157.8	0	0	0	110.3	F105 W106 A171 M172 E178 M179	F105-I175 HydrophobicContact CE2-CD1 3.95Å; W106-I175 HydrophobicContact CD2-CG2 4.37Å; W106-I175 HydrophobicContact CE3-CG2 4.2Å; W106-I175 HydrophobicContact CH2-CG2 4.02Å; W106-I175 HydrophobicContact CZ2-CG2 4.22Å; W106-I175 HydrophobicContact CZ3-CG2 4.02Å; W106-I175 WeakPolarHBondContact O-CD1 3.42Å; A171-I175 PolarHBondContact O-N 3.09Å; M172-I175 HydrophobicContact CE-CB 4.4Å; M172-I175 HydrophobicContact CE-CD1 4.07Å; M172-I175 HydrophobicContact CE-CG2 4.38Å; M172-I175 CarbonylContact O-C 3.55Å; M172-I175 WeakPolarHBondContact O-CA 3.42Å; M172-I175 WeakPolarHBondContact O-CB 3.36Å; M172-I175 PolarHBondContact O-N 3.04Å; M172-I175 HydrophobicContact SD-CD1 3.83Å; I175-E178 PolarHBondContact O-N 3.05Å; I175-M179 WeakPolarHBondContact O-CB 3.47Å; I175-M179 PolarHBondContact O-N 2.94Å
176	H	96.9	Very high	96	Very high	0 Å²	0	29.4 Å²	29.4	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-61.8	-48.1	173.8	-62	-178.8	0	0	0	110.9	W106 D142 M172 E173 E178 M179 Y180 D269 E270	W106-H176 AromaticContact CZ2-CD2 3.56Å; W106-H176 AromaticContact CZ2-NE2 3.94Å; D142-H176 WeakPolarHBondContact OD2-CB 3.33Å; M172-H176 PolarHBondContact O-CD2 3.42Å; M172-H176 PolarHBondContact O-N 2.9Å; E173-H176 PolarHBondContact O-N 3.4Å; H176-E178 VanDerWaalsContact C-N 3.3Å; H176-E178 PolarHBondContact O-N 3.32Å; H176-M179 WeakPolarHBondContact O-CB 3.35Å; H176-M179 PolarHBondContact O-N 3.43Å; H176-M179 VanDerWaalsContact O-N 3.09Å; H176-Y180 HydrophobicContact CB-CE2 4.28Å; H176-Y180 WeakPolarHBondContact O-CD2 3.46Å; H176-Y180 PolarHBondContact O-N 3.03Å; H176-D269 IonicContact CE1-OD2 3.53Å; H176-D269 IonicContact NE2-OD2 3.7Å; H176-D269 PolarHBondContact NE2-OD2 3.1Å; H176-E270 IonicContact CE1-OE1 3.72Å; H176-E270 PolarHBondContact CE1-OE1 3.01Å; H176-E270 VanDerWaalsContact CE1-OE1 3.26Å; H176-E270 IonicContact ND1-OE1 2.57Å; H176-E270 PolarHBondContact ND1-OE1 2.85Å
177	S	94	Very high	95.9	Very high	26 Å²	26	29.5 Å²	29.5	18%	0.182	17%	0.174	C	C	.	.	H	α-helix	trans	-57.6	-41.1	175.6	-67.1	0	0	0	0	112.6	D142 E173 N174 S181	D142-S177 WeakPolarHBondContact CB-OG 3.39Å; E173-S177 WeakPolarHBondContact O-CB 3.28Å; E173-S177 PolarHBondContact O-N 2.79Å; E173-S177 PolarHBondContact O-OG 3.23Å; N174-S177 PolarHBondContact O-N 3.35Å; S177-S181 WeakPolarHBondContact O-CB 3.34Å; S177-S181 PolarHBondContact O-N 3.19Å; S177-S181 VanDerWaalsContact O-N 3.09Å; S177-S181 PolarHBondContact O-OG 3Å
178	E	96.3	Very high	95.8	Very high	99 Å²	99	27.9 Å²	27.9	46%	0.463	16%	0.156	S	C	.	.	H	α-helix	trans	-64.1	-47.2	173.7	175.7	170.8	-143.1	0	0	111.4	A108 N174 I175 H176 Y180 S181 L182	A108-E178 HydrophobicContact CB-CG 4.09Å; N174-E178 WeakPolarHBondContact O-CB 3.49Å; N174-E178 PolarHBondContact O-N 2.89Å; I175-E178 PolarHBondContact O-N 3.05Å; H176-E178 VanDerWaalsContact C-N 3.3Å; H176-E178 PolarHBondContact O-N 3.32Å; E178-Y180 PolarHBondContact O-N 2.98Å; E178-S181 WeakPolarHBondContact O-CB 3.43Å; E178-S181 PolarHBondContact O-N 3.37Å; E178-L182 WeakPolarHBondContact O-CB 3.08Å; E178-L182 PolarHBondContact O-N 3.22Å
179	M	97.6	Very high	95.6	Very high	0 Å²	0	32.5 Å²	32.5	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-59.6	-47	179.6	-170.2	67.2	-112.4	0	0	111.6	W106 A108 V111 L113 I175 H176 S181 L182 L183 I266	W106-M179 HydrophobicContact CH2-CB 4.11Å; W106-M179 HydrophobicContact CH2-CG 4.04Å; W106-M179 HydrophobicContact CZ3-CB 4.5Å; W106-M179 HydrophobicContact CZ3-CG 4.27Å; W106-M179 HydrophobicContact CZ3-SD 4.2Å; A108-M179 HydrophobicContact CB-SD 4.15Å; V111-M179 HydrophobicContact CB-CE 4.11Å; V111-M179 HydrophobicContact CB-SD 3.8Å; V111-M179 HydrophobicContact CG1-CE 3.92Å; V111-M179 HydrophobicContact CG1-SD 4.11Å; V111-M179 HydrophobicContact CG2-SD 3.66Å; L113-M179 HydrophobicContact CD1-CE 4.04Å; L113-M179 HydrophobicContact CD2-CE 4.17Å; L113-M179 HydrophobicContact CG-CE 4.42Å; I175-M179 WeakPolarHBondContact O-CB 3.47Å; I175-M179 PolarHBondContact O-N 2.94Å; H176-M179 WeakPolarHBondContact O-CB 3.35Å; H176-M179 PolarHBondContact O-N 3.43Å; H176-M179 VanDerWaalsContact O-N 3.09Å; M179-S181 VanDerWaalsContact C-N 3.33Å; M179-S181 PolarHBondContact O-N 3.12Å; M179-L182 HydrophobicContact CE-CB 4.4Å; M179-L182 HydrophobicContact CE-CD2 4Å; M179-L182 HydrophobicContact CE-CG 4.44Å; M179-L182 PolarHBondContact O-N 2.94Å; M179-L183 HydrophobicContact CE-CD1 4.23Å; M179-L183 HydrophobicContact CE-CD2 3.97Å; M179-L183 HydrophobicContact CE-CG 3.72Å; M179-L183 HydrophobicContact CG-CD1 4.34Å; M179-L183 VanDerWaalsContact O-CG 3.27Å; M179-L183 WeakPolarHBondContact O-CG 3.32Å; M179-L183 PolarHBondContact O-N 3.45Å; M179-I266 HydrophobicContact CG-CD1 4.32Å
180	Y	96.2	Very high	95.4	Very high	5 Å²	5	35.8 Å²	35.8	2%	0.02	19%	0.193	C	C	.	.	H	α-helix	trans	-63.8	-38.9	176.2	-68.7	-55.5	0	0	0	112.4	L135 F138 D142 H176 E178 L182 L183 I184 I266	L135-Y180 HydrophobicContact CD2-CD1 3.82Å; L135-Y180 HydrophobicContact CD2-CE1 4.32Å; F138-Y180 HydrophobicContact CB-CD1 3.75Å; F138-Y180 HydrophobicContact CB-CD2 3.72Å; F138-Y180 HydrophobicContact CB-CE1 3.6Å; F138-Y180 HydrophobicContact CB-CE2 3.57Å; F138-Y180 HydrophobicContact CB-CG 3.81Å; F138-Y180 VanDerWaalsContact CB-CZ 3.48Å; F138-Y180 HydrophobicContact CD1-CE1 4.43Å; F138-Y180 HydrophobicContact CD1-CE2 4.33Å; F138-Y180 AromaticContact CD1-CZ 3.86Å; F138-Y180 WeakPolarHBondContact CD1-OH 2.99Å; F138-Y180 HydrophobicContact CD2-CD1 4.17Å; F138-Y180 AromaticContact CD2-CE1 3.46Å; F138-Y180 HydrophobicContact CD2-CE1 3.46Å; F138-Y180 VanDerWaalsContact CD2-CE1 3.46Å; F138-Y180 AromaticContact CD2-CZ 3.73Å; F138-Y180 HydrophobicContact CE2-CE1 4.16Å; F138-Y180 HydrophobicContact CG-CD1 4.26Å; F138-Y180 AromaticContact CG-CE1 3.62Å; F138-Y180 HydrophobicContact CG-CE1 3.62Å; F138-Y180 HydrophobicContact CG-CE2 4.01Å; F138-Y180 AromaticContact CG-CZ 3.46Å; F138-Y180 VanDerWaalsContact CG-CZ 3.46Å; D142-Y180 WeakPolarHBondContact OD2-CD2 3.47Å; D142-Y180 WeakPolarHBondContact OD2-CE2 3.37Å; H176-Y180 HydrophobicContact CB-CE2 4.28Å; H176-Y180 WeakPolarHBondContact O-CD2 3.46Å; H176-Y180 PolarHBondContact O-N 3.03Å; E178-Y180 PolarHBondContact O-N 2.98Å; Y180-L182 VanDerWaalsContact C-N 3.35Å; Y180-L183 HydrophobicContact CD1-CD1 4.16Å; Y180-L183 PolarHBondContact O-N 2.73Å; Y180-I184 WeakPolarHBondContact O-CG1 3.43Å; Y180-I184 PolarHBondContact O-N 3.01Å; Y180-I266 HydrophobicContact CE1-CD1 3.94Å; Y180-I266 HydrophobicContact CE2-CD1 3.99Å; Y180-I266 WeakPolarHBondContact OH-CG2 3.38Å
181	S	92.7	Very high	95.1	Very high	48 Å²	48	38.6 Å²	38.6	34%	0.336	21%	0.214	S	C	.	.	H	α-helix	trans	-63.2	-42.3	175	-60.4	0	0	0	0	111.5	S177 E178 M179 I184 D185	S177-S181 WeakPolarHBondContact O-CB 3.34Å; S177-S181 PolarHBondContact O-N 3.19Å; S177-S181 VanDerWaalsContact O-N 3.09Å; S177-S181 PolarHBondContact O-OG 3Å; E178-S181 WeakPolarHBondContact O-CB 3.43Å; E178-S181 PolarHBondContact O-N 3.37Å; M179-S181 VanDerWaalsContact C-N 3.33Å; M179-S181 PolarHBondContact O-N 3.12Å; S181-I184 PolarHBondContact O-N 2.94Å; S181-D185 VanDerWaalsContact O-CB 3.32Å; S181-D185 WeakPolarHBondContact O-CB 3.2Å; S181-D185 PolarHBondContact O-N 3.46Å
182	L	95.3	Very high	94.8	Very high	67 Å²	67	40.2 Å²	40.2	35%	0.351	22%	0.222	S	C	.	.	H	α-helix	trans	-65.1	-40.9	177.1	-178.4	63.8	0	0	0	111.9	L113 E178 M179 Y180 D185 T186	L113-L182 HydrophobicContact CD1-CD2 3.93Å; L113-L182 HydrophobicContact CD1-CG 3.74Å; E178-L182 WeakPolarHBondContact O-CB 3.08Å; E178-L182 PolarHBondContact O-N 3.22Å; M179-L182 HydrophobicContact CE-CB 4.4Å; M179-L182 HydrophobicContact CE-CD2 4Å; M179-L182 HydrophobicContact CE-CG 4.44Å; M179-L182 PolarHBondContact O-N 2.94Å; Y180-L182 VanDerWaalsContact C-N 3.35Å; L182-D185 PolarHBondContact O-N 3.03Å; L182-T186 VanDerWaalsContact O-CB 3.29Å; L182-T186 WeakPolarHBondContact O-CB 3.43Å; L182-T186 PolarHBondContact O-N 3.4Å; L182-T186 PolarHBondContact O-OG1 3.14Å
183	L	97	Very high	94.5	Very high	1 Å²	1	44 Å²	44	1%	0.005	24%	0.24	C	C	.	.	H	α-helix	trans	-60.7	-48.5	174.5	-70	164.8	0	0	0	111	L113 L135 M179 Y180 D185 T186 Y187 L259	L113-L183 HydrophobicContact CD1-CD2 4.25Å; L113-L183 HydrophobicContact CD2-CD2 3.73Å; L135-L183 HydrophobicContact CD1-CB 4.05Å; L135-L183 HydrophobicContact CD2-CB 4.14Å; L135-L183 HydrophobicContact CD2-CD1 3.82Å; M179-L183 HydrophobicContact CE-CD1 4.23Å; M179-L183 HydrophobicContact CE-CD2 3.97Å; M179-L183 HydrophobicContact CE-CG 3.72Å; M179-L183 HydrophobicContact CG-CD1 4.34Å; M179-L183 VanDerWaalsContact O-CG 3.27Å; M179-L183 WeakPolarHBondContact O-CG 3.32Å; M179-L183 PolarHBondContact O-N 3.45Å; Y180-L183 HydrophobicContact CD1-CD1 4.16Å; Y180-L183 PolarHBondContact O-N 2.73Å; L183-D185 PolarHBondContact O-N 3.15Å; L183-T186 PolarHBondContact O-N 3.48Å; L183-Y187 HydrophobicContact CB-CD2 4.46Å; L183-Y187 HydrophobicContact CB-CE2 3.99Å; L183-Y187 HydrophobicContact CD2-CE2 3.81Å; L183-Y187 WeakPolarHBondContact CD2-OH 3.38Å; L183-Y187 WeakPolarHBondContact O-CB 3.35Å; L183-Y187 WeakPolarHBondContact O-CD2 3.48Å; L183-Y187 PolarHBondContact O-N 2.96Å; L183-L259 HydrophobicContact CD1-CD1 3.91Å; L183-L259 HydrophobicContact CD2-CB 4.44Å; L183-L259 HydrophobicContact CD2-CD1 4.26Å
184	I	94.2	Very high	94.3	Very high	1 Å²	1	46.7 Å²	46.7	1%	0.005	25%	0.25	C	S	.	.	H	α-helix	trans	-60.7	-46.4	176.8	-69.8	169.4	0	0	0	110.8	L135 A139 Y180 S181 T186 Y187 I188 R194 F198	L135-I184 HydrophobicContact CB-CD1 4.14Å; L135-I184 HydrophobicContact CB-CG1 3.77Å; L135-I184 HydrophobicContact CD1-CG1 4.4Å; A139-I184 HydrophobicContact CB-CD1 3.99Å; Y180-I184 WeakPolarHBondContact O-CG1 3.43Å; Y180-I184 PolarHBondContact O-N 3.01Å; S181-I184 PolarHBondContact O-N 2.94Å; I184-T186 VanDerWaalsContact C-N 3.28Å; I184-T186 PolarHBondContact O-N 3.06Å; I184-Y187 PolarHBondContact O-N 2.78Å; I184-I188 HydrophobicContact CG2-CG1 4.25Å; I184-I188 VanDerWaalsContact O-CB 3.28Å; I184-I188 WeakPolarHBondContact O-CB 3.48Å; I184-I188 WeakPolarHBondContact O-CG1 3.45Å; I184-I188 PolarHBondContact O-N 3.42Å; I184-R194 HydrophobicContact CG2-CG 3.84Å; I184-F198 HydrophobicContact CB-CE1 4.22Å; I184-F198 HydrophobicContact CB-CZ 4.19Å; I184-F198 HydrophobicContact CD1-CD1 4.19Å; I184-F198 HydrophobicContact CD1-CE1 3.75Å; I184-F198 HydrophobicContact CG2-CE1 4Å; I184-F198 HydrophobicContact CG2-CE2 4.31Å; I184-F198 HydrophobicContact CG2-CZ 3.78Å
185	D	93.1	Very high	93.9	Very high	79 Å²	79	47.3 Å²	47.3	42%	0.422	25%	0.25	S	S	.	.	H	α-helix	trans	-61.2	-39.2	-179.7	-161.9	73.9	0	0	0	112.1	S181 L182 L183 R194	S181-D185 VanDerWaalsContact O-CB 3.32Å; S181-D185 WeakPolarHBondContact O-CB 3.2Å; S181-D185 PolarHBondContact O-N 3.46Å; L182-D185 PolarHBondContact O-N 3.03Å; L183-D185 PolarHBondContact O-N 3.15Å; D185-R194 IonicContact OD1-CZ 3.27Å; D185-R194 IonicContact OD1-NE 3.16Å; D185-R194 IonicContact OD1-NH1 2.69Å; D185-R194 PolarHBondContact OD1-NH1 3.3Å; D185-R194 IonicContact OD1-NH2 3.39Å
186	T	94.9	Very high	93.5	Very high	35 Å²	35	51.2 Å²	51.2	22%	0.215	26%	0.264	C	S	.	.	H	α-helix	trans	-69.7	-43.5	179.8	-58.1	0	0	0	0	111.9	L113 L182 L183 I184	L113-T186 HydrophobicContact CB-CG2 4.43Å; L113-T186 HydrophobicContact CD1-CG2 4.41Å; L182-T186 VanDerWaalsContact O-CB 3.29Å; L182-T186 WeakPolarHBondContact O-CB 3.43Å; L182-T186 PolarHBondContact O-N 3.4Å; L182-T186 PolarHBondContact O-OG1 3.14Å; L183-T186 PolarHBondContact O-N 3.48Å; I184-T186 VanDerWaalsContact C-N 3.28Å; I184-T186 PolarHBondContact O-N 3.06Å
187	Y	95.8	Very high	92.9	Very high	5 Å²	5	51.2 Å²	51.2	2%	0.02	27%	0.265	C	S	.	.	H	α-helix	trans	-86.5	-34.3	-172.6	-56.3	-21.6	0	0	0	112.9	D116 W120 L135 L183 I184 M256 L259	D116-Y187 HydrophobicContact CB-CE1 3.6Å; D116-Y187 PolarHBondContact OD1-OH 3.35Å; W120-Y187 HydrophobicContact CD2-CG 4.16Å; W120-Y187 HydrophobicContact CE3-CD2 4.25Å; W120-Y187 HydrophobicContact CE3-CG 4.14Å; W120-Y187 HydrophobicContact CZ3-CD2 4.32Å; W120-Y187 PolarHBondContact NE1-O 3.39Å; L135-Y187 HydrophobicContact CD1-CD2 3.74Å; L135-Y187 HydrophobicContact CD1-CE2 3.92Å; L183-Y187 HydrophobicContact CB-CD2 4.46Å; L183-Y187 HydrophobicContact CB-CE2 3.99Å; L183-Y187 HydrophobicContact CD2-CE2 3.81Å; L183-Y187 WeakPolarHBondContact CD2-OH 3.38Å; L183-Y187 WeakPolarHBondContact O-CB 3.35Å; L183-Y187 WeakPolarHBondContact O-CD2 3.48Å; L183-Y187 PolarHBondContact O-N 2.96Å; I184-Y187 PolarHBondContact O-N 2.78Å; Y187-M256 HydrophobicContact CD1-CE 4.18Å; Y187-M256 HydrophobicContact CD2-CE 4.36Å; Y187-M256 HydrophobicContact CE1-CE 3.63Å; Y187-M256 HydrophobicContact CE2-CE 3.81Å; Y187-L259 WeakPolarHBondContact OH-CB 3.45Å
188	I	94.8	Very high	92.3	Very high	5 Å²	5	53.4 Å²	53.4	3%	0.026	27%	0.271	C	S	.	.			trans	-103.3	94.2	-172.7	-48	-57.7	0	0	0	109.5	W120 I184 E193 R194 L197	W120-I188 HydrophobicContact CH2-CD1 4.29Å; W120-I188 HydrophobicContact CZ2-CD1 3.7Å; I184-I188 HydrophobicContact CG2-CG1 4.25Å; I184-I188 VanDerWaalsContact O-CB 3.28Å; I184-I188 WeakPolarHBondContact O-CB 3.48Å; I184-I188 WeakPolarHBondContact O-CG1 3.45Å; I184-I188 PolarHBondContact O-N 3.42Å; I188-E193 HydrophobicContact CG2-CB 3.77Å; I188-E193 HydrophobicContact CG2-CG 3.71Å; I188-R194 HydrophobicContact CG2-CB 4.21Å; I188-R194 PolarHBondContact O-NE 2.96Å; I188-R194 PolarHBondContact O-NH2 3.01Å; I188-L197 HydrophobicContact CD1-CD1 4.19Å; I188-L197 HydrophobicContact CG1-CD1 3.87Å; I188-L197 HydrophobicContact CG2-CD1 4.39Å
189	K	91.2	Very high	91.7	Very high	128 Å²	128	49.9 Å²	49.9	56%	0.557	26%	0.255	S	S	*	.			trans	-72.1	-31.2	-179.1	-66.3	-178.3	-173	166.2	0	112.9	E121 P191	E121-K189 IonicContact OE1-NZ 2.77Å; E121-K189 PolarHBondContact OE1-NZ 3.18Å; K189-P191 WeakPolarHBondContact O-CD 3.47Å
190	D	93.1	Very high	90.8	Very high	71 Å²	71	49.9 Å²	49.9	38%	0.38	26%	0.255	S	S	.	.			trans	-76.4	119.4	179.8	177.4	37.2	0	0	0	111.2	S192 E193 R194	D190-S192 PolarHBondContact O-N 2.8Å; D190-S192 PolarHBondContact OD1-N 3.26Å; D190-S192 PolarHBondContact OD2-OG 2.85Å; D190-E193 HydrophobicContact CB-CB 4.07Å; D190-E193 PolarHBondContact O-N 3.39Å; D190-E193 PolarHBondContact OD2-N 3.12Å; D190-R194 WeakPolarHBondContact O-CB 3.47Å; D190-R194 PolarHBondContact O-N 3.49Å
191	P	91	Very high	89.8	Confident	88 Å²	88	52.2 Å²	52.2	57%	0.571	27%	0.268	S	S	*	.	H	α-helix	trans	-61.4	-30.4	178.8	-23.7	34.9	0	0	0	113.5	K189 R194 E195	K189-P191 WeakPolarHBondContact O-CD 3.47Å; P191-R194 PolarHBondContact O-N 3.25Å; P191-E195 PolarHBondContact O-N 2.71Å
192	S	91.4	Very high	89.2	Confident	77 Å²	77	55.5 Å²	55.5	54%	0.538	28%	0.277	S	S	.	.	H	α-helix	trans	-73.3	-42.7	-178.1	86.1	0	0	0	0	112	D190 R194 E195 Y196	D190-S192 PolarHBondContact O-N 2.8Å; D190-S192 PolarHBondContact OD1-N 3.26Å; D190-S192 PolarHBondContact OD2-OG 2.85Å; S192-R194 VanDerWaalsContact C-N 3.32Å; S192-R194 PolarHBondContact O-N 3.42Å; S192-E195 PolarHBondContact O-N 3Å; S192-Y196 PolarHBondContact O-N 3.29Å
193	E	90.5	Very high	88.4	Confident	84 Å²	84	54.5 Å²	54.5	39%	0.393	27%	0.274	S	S	.	.	H	α-helix	trans	-61.4	-41.3	170.1	-172.3	178.4	-174.2	0	0	111.3	I188 D190 E195 Y196 L197	I188-E193 HydrophobicContact CG2-CB 3.77Å; I188-E193 HydrophobicContact CG2-CG 3.71Å; D190-E193 HydrophobicContact CB-CB 4.07Å; D190-E193 PolarHBondContact O-N 3.39Å; D190-E193 PolarHBondContact OD2-N 3.12Å; E193-E195 PolarHBondContact O-N 3.36Å; E193-Y196 WeakPolarHBondContact O-CB 3.31Å; E193-Y196 PolarHBondContact O-N 2.97Å; E193-L197 HydrophobicContact CG-CD1 4.18Å; E193-L197 WeakPolarHBondContact O-CG 3.32Å; E193-L197 PolarHBondContact O-N 3.37Å
194	R	90.1	Very high	87.5	Confident	56 Å²	56	55 Å²	55	21%	0.211	28%	0.277	C	S	.	.	H	α-helix	trans	-60.7	-45.7	177	-161.9	-174.1	-58	164.9	1.7	112.2	I184 D185 I188 D190 P191 S192 Y196 L197 F198	I184-R194 HydrophobicContact CG2-CG 3.84Å; D185-R194 IonicContact OD1-CZ 3.27Å; D185-R194 IonicContact OD1-NE 3.16Å; D185-R194 IonicContact OD1-NH1 2.69Å; D185-R194 PolarHBondContact OD1-NH1 3.3Å; D185-R194 IonicContact OD1-NH2 3.39Å; I188-R194 HydrophobicContact CG2-CB 4.21Å; I188-R194 PolarHBondContact O-NE 2.96Å; I188-R194 PolarHBondContact O-NH2 3.01Å; D190-R194 WeakPolarHBondContact O-CB 3.47Å; D190-R194 PolarHBondContact O-N 3.49Å; P191-R194 PolarHBondContact O-N 3.25Å; S192-R194 VanDerWaalsContact C-N 3.32Å; S192-R194 PolarHBondContact O-N 3.42Å; R194-Y196 VanDerWaalsContact C-N 3.33Å; R194-Y196 PolarHBondContact O-N 3.08Å; R194-L197 PolarHBondContact O-N 3.22Å; R194-F198 HydrophobicContact CG-CD2 3.81Å; R194-F198 HydrophobicContact CG-CE2 3.4Å; R194-F198 VanDerWaalsContact CG-CE2 3.4Å; R194-F198 HydrophobicContact CG-CZ 4.18Å; R194-F198 VanDerWaalsContact O-CD2 3.29Å; R194-F198 WeakPolarHBondContact O-CD2 3.45Å; R194-F198 PolarHBondContact O-N 2.98Å
195	E	88	Confident	87	Confident	98 Å²	98	60.1 Å²	60.1	46%	0.458	31%	0.31	S	S	.	.	H	α-helix	trans	-63.9	-38.6	176	-177.1	172.5	-164.2	0	0	111.9	P191 S192 E193 N199	P191-E195 PolarHBondContact O-N 2.71Å; S192-E195 PolarHBondContact O-N 3Å; E193-E195 PolarHBondContact O-N 3.36Å; E195-N199 PolarHBondContact O-N 3.17Å; E195-N199 PolarHBondContact O-ND2 3.02Å
196	Y	88.6	Confident	86.1	Confident	102 Å²	102	57.8 Å²	57.8	40%	0.4	30%	0.3	S	S	.	.	H	α-helix	trans	-60.6	-44.9	175.1	173.3	-96.6	0	0	0	112.2	S192 E193 R194 N199 T203 L204	S192-Y196 PolarHBondContact O-N 3.29Å; E193-Y196 WeakPolarHBondContact O-CB 3.31Å; E193-Y196 PolarHBondContact O-N 2.97Å; R194-Y196 VanDerWaalsContact C-N 3.33Å; R194-Y196 PolarHBondContact O-N 3.08Å; Y196-N199 PolarHBondContact O-N 3.25Å; Y196-T203 HydrophobicContact CD2-CG2 3.94Å; Y196-T203 HydrophobicContact CE2-CG2 4.04Å; Y196-T203 PolarHBondContact O-OG1 3.21Å; Y196-L204 HydrophobicContact CE1-CD2 4.15Å; Y196-L204 VanDerWaalsContact OH-CD2 3.26Å; Y196-L204 WeakPolarHBondContact OH-CD2 3.4Å
197	L	85.4	Confident	85.4	Confident	1 Å²	1	56.2 Å²	56.2	1%	0.005	29%	0.29	C	S	.	.	H	α-helix	trans	-70.4	-41.9	180	-68.3	172.5	0	0	0	112	A136 I188 E193 R194 N199 A200	A136-L197 HydrophobicContact CB-CB 3.89Å; A136-L197 HydrophobicContact CB-CD2 3.86Å; A136-L197 HydrophobicContact CB-CG 4.43Å; A136-L197 WeakPolarHBondContact CB-O 3.35Å; I188-L197 HydrophobicContact CD1-CD1 4.19Å; I188-L197 HydrophobicContact CG1-CD1 3.87Å; I188-L197 HydrophobicContact CG2-CD1 4.39Å; E193-L197 HydrophobicContact CG-CD1 4.18Å; E193-L197 WeakPolarHBondContact O-CG 3.32Å; E193-L197 PolarHBondContact O-N 3.37Å; R194-L197 PolarHBondContact O-N 3.22Å; L197-N199 PolarHBondContact O-N 3.33Å; L197-A200 WeakPolarHBondContact O-CB 3.3Å; L197-A200 PolarHBondContact O-N 3.03Å
198	F	82.3	Confident	85	Confident	71 Å²	71	61 Å²	61	31%	0.311	31%	0.311	S	S	.	.	H	α-helix	trans	-65	-22.1	176	-74.9	-45.6	0	0	0	113.5	T45 I184 R194 A200	T45-F198 HydrophobicContact CG2-CB 4.44Å; I184-F198 HydrophobicContact CB-CE1 4.22Å; I184-F198 HydrophobicContact CB-CZ 4.19Å; I184-F198 HydrophobicContact CD1-CD1 4.19Å; I184-F198 HydrophobicContact CD1-CE1 3.75Å; I184-F198 HydrophobicContact CG2-CE1 4Å; I184-F198 HydrophobicContact CG2-CE2 4.31Å; I184-F198 HydrophobicContact CG2-CZ 3.78Å; R194-F198 HydrophobicContact CG-CD2 3.81Å; R194-F198 HydrophobicContact CG-CE2 3.4Å; R194-F198 VanDerWaalsContact CG-CE2 3.4Å; R194-F198 HydrophobicContact CG-CZ 4.18Å; R194-F198 VanDerWaalsContact O-CD2 3.29Å; R194-F198 WeakPolarHBondContact O-CD2 3.45Å; R194-F198 PolarHBondContact O-N 2.98Å; F198-A200 VanDerWaalsContact C-N 3.32Å
199	N	83	Confident	84.7	Confident	26 Å²	26	65 Å²	65	14%	0.139	33%	0.328	C	S	.	.	T	Hydrogen-bonded Turn	trans	-94.2	21.9	174.5	-67.6	-54.8	0	0	0	113.1	E195 Y196 L197 I201 Q202 T203	E195-N199 PolarHBondContact O-N 3.17Å; E195-N199 PolarHBondContact O-ND2 3.02Å; Y196-N199 PolarHBondContact O-N 3.25Å; L197-N199 PolarHBondContact O-N 3.33Å; N199-I201 PolarHBondContact O-N 2.79Å; N199-Q202 PolarHBondContact O-N 3.47Å; N199-T203 HydrophobicContact CB-CG2 4.01Å; N199-T203 PolarHBondContact O-N 3.3Å; N199-T203 PolarHBondContact O-OG1 2.98Å; N199-T203 VanDerWaalsContact O-OG1 3.06Å
200	A	77.9	Confident	84.6	Confident	0 Å²	0	59 Å²	59	0%	0	30%	0.302	C	S	.	.	H	α-helix	trans	-46.6	-37.8	-175	0	0	0	0	0	115.3	A136 L197 F198 Q202 T203 L204 V207	A136-A200 HydrophobicContact CB-CB 4.08Å; L197-A200 WeakPolarHBondContact O-CB 3.3Å; L197-A200 PolarHBondContact O-N 3.03Å; F198-A200 VanDerWaalsContact C-N 3.32Å; A200-Q202 PolarHBondContact O-N 3.02Å; A200-T203 VanDerWaalsContact CA-OG1 3.25Å; A200-T203 WeakPolarHBondContact CA-OG1 3.2Å; A200-T203 PolarHBondContact N-OG1 3Å; A200-T203 PolarHBondContact O-N 3.1Å; A200-L204 HydrophobicContact CB-CD1 3.91Å; A200-L204 HydrophobicContact CB-CG 4.4Å; A200-L204 WeakPolarHBondContact O-CA 2.93Å; A200-L204 VanDerWaalsContact O-CB 3.31Å; A200-L204 WeakPolarHBondContact O-CB 3.47Å; A200-L204 PolarHBondContact O-N 3.3Å; A200-V207 HydrophobicContact CB-CB 4.47Å; A200-V207 HydrophobicContact CB-CG1 4.15Å; A200-V207 HydrophobicContact CB-CG2 4.3Å
201	I	76	Confident	84.4	Confident	54 Å²	54	55.8 Å²	55.8	28%	0.277	29%	0.285	S	S	.	.	H	α-helix	trans	-60	-35.6	178.3	-61.2	172.3	0	0	0	111.5	A140 I144 N199 V207 A211	A140-I201 HydrophobicContact CB-CD1 3.96Å; A140-I201 HydrophobicContact CB-CG1 3.72Å; I144-I201 HydrophobicContact CD1-CD1 3.95Å; I144-I201 HydrophobicContact CG1-CD1 4.48Å; N199-I201 PolarHBondContact O-N 2.79Å; I201-V207 HydrophobicContact CG1-CG1 4.2Å; I201-A211 HydrophobicContact CG1-CB 4.36Å; I201-A211 HydrophobicContact CG2-CB 4.23Å
202	Q	80.6	Confident	84.3	Confident	116 Å²	116	55.5 Å²	55.5	54%	0.542	28%	0.279	S	S	.	.	H	α-helix	trans	-90.8	-29.4	-179.7	-60.9	-175.5	2.1	0	0	112.3	T52 N199 A200	T52-Q202 PolarHBondContact OG1-NE2 3.17Å; N199-Q202 PolarHBondContact O-N 3.47Å; A200-Q202 PolarHBondContact O-N 3.02Å
203	T	77.7	Confident	84.4	Confident	47 Å²	47	53.1 Å²	53.1	29%	0.288	26%	0.258	S	S	.	.	H	α-helix	trans	-98.2	-25.4	-171	57.7	0	0	0	0	113.8	Y196 N199 A200	Y196-T203 HydrophobicContact CD2-CG2 3.94Å; Y196-T203 HydrophobicContact CE2-CG2 4.04Å; Y196-T203 PolarHBondContact O-OG1 3.21Å; N199-T203 HydrophobicContact CB-CG2 4.01Å; N199-T203 PolarHBondContact O-N 3.3Å; N199-T203 PolarHBondContact O-OG1 2.98Å; N199-T203 VanDerWaalsContact O-OG1 3.06Å; A200-T203 VanDerWaalsContact CA-OG1 3.25Å; A200-T203 WeakPolarHBondContact CA-OG1 3.2Å; A200-T203 PolarHBondContact N-OG1 3Å; A200-T203 PolarHBondContact O-N 3.1Å
204	L	77.8	Confident	84.4	Confident	10 Å²	10	49.7 Å²	49.7	5%	0.052	24%	0.244	C	C	.	.			trans	-115.2	107.5	-176.1	-62.2	178	0	0	0	111.2	Y196 A200 C206 V207 K208	Y196-L204 HydrophobicContact CE1-CD2 4.15Å; Y196-L204 VanDerWaalsContact OH-CD2 3.26Å; Y196-L204 WeakPolarHBondContact OH-CD2 3.4Å; A200-L204 HydrophobicContact CB-CD1 3.91Å; A200-L204 HydrophobicContact CB-CG 4.4Å; A200-L204 WeakPolarHBondContact O-CA 2.93Å; A200-L204 VanDerWaalsContact O-CB 3.31Å; A200-L204 WeakPolarHBondContact O-CB 3.47Å; A200-L204 PolarHBondContact O-N 3.3Å; L204-C206 PolarHBondContact O-N 3.31Å; L204-C206 VanDerWaalsContact O-N 3.14Å; L204-V207 HydrophobicContact CB-CB 4.05Å; L204-V207 HydrophobicContact CB-CG2 3.84Å; L204-V207 HydrophobicContact CD1-CG2 3.97Å; L204-V207 PolarHBondContact O-N 2.88Å; L204-V207 VanDerWaalsContact O-N 3.12Å; L204-K208 PolarHBondContact O-N 2.98Å
205	P	83.1	Confident	84.2	Confident	109 Å²	109	49 Å²	49	71%	0.708	24%	0.244	S	C	*	.	H	α-helix	trans	-56.2	-32.7	-179.9	-27.4	35.1	0	0	0	114.2	K208 K209	P205-K208 WeakPolarHBondContact O-CB 3.27Å; P205-K208 PolarHBondContact O-N 3.48Å; P205-K209 PolarHBondContact O-N 3.18Å
206	C	75.3	Confident	84.4	Confident	30 Å²	30	48.6 Å²	48.6	20%	0.203	25%	0.245	C	C	.	.	H	α-helix	trans	-71.4	-35.7	-179.6	61.8	0	0	0	0	113.2	L204 F307 A311	L204-C206 PolarHBondContact O-N 3.31Å; L204-C206 VanDerWaalsContact O-N 3.14Å; C206-F307 HydrophobicContact CB-CD2 4.02Å; C206-F307 HydrophobicContact CB-CE2 4.35Å; C206-A311 HydrophobicContact CB-CB 3.22Å
207	V	80.9	Confident	84.4	Confident	2 Å²	2	45.7 Å²	45.7	1%	0.012	23%	0.234	C	C	.	.	H	α-helix	trans	-70.1	-41.4	172.1	173.8	0	0	0	0	109.9	F137 A140 A200 I201 L204 K209 K210 A211 F307	F137-V207 HydrophobicContact CB-CG2 3.94Å; F137-V207 HydrophobicContact CD2-CB 4.32Å; F137-V207 HydrophobicContact CD2-CG1 3.99Å; F137-V207 HydrophobicContact CD2-CG2 3.97Å; F137-V207 HydrophobicContact CG-CG2 4.42Å; A140-V207 HydrophobicContact CB-CG1 4.44Å; A200-V207 HydrophobicContact CB-CB 4.47Å; A200-V207 HydrophobicContact CB-CG1 4.15Å; A200-V207 HydrophobicContact CB-CG2 4.3Å; I201-V207 HydrophobicContact CG1-CG1 4.2Å; L204-V207 HydrophobicContact CB-CB 4.05Å; L204-V207 HydrophobicContact CB-CG2 3.84Å; L204-V207 HydrophobicContact CD1-CG2 3.97Å; L204-V207 PolarHBondContact O-N 2.88Å; L204-V207 VanDerWaalsContact O-N 3.12Å; V207-K209 VanDerWaalsContact C-N 3.34Å; V207-K209 PolarHBondContact O-N 3.43Å; V207-K210 PolarHBondContact O-N 3.34Å; V207-A211 WeakPolarHBondContact O-CB 3.12Å; V207-A211 PolarHBondContact O-N 3.4Å; V207-F307 HydrophobicContact CG2-CE2 4.47Å
208	K	86.9	Confident	84.2	Confident	106 Å²	106	46.1 Å²	46.1	46%	0.461	24%	0.236	S	C	.	.	H	α-helix	trans	-56.1	-44.4	178.8	-173.3	177.9	177	-179.3	0	112.7	L204 P205 K210 A211 D212	L204-K208 PolarHBondContact O-N 2.98Å; P205-K208 WeakPolarHBondContact O-CB 3.27Å; P205-K208 PolarHBondContact O-N 3.48Å; K208-K210 PolarHBondContact O-N 3.49Å; K208-A211 PolarHBondContact O-N 3.02Å; K208-D212 WeakPolarHBondContact CE-OD2 3.35Å; K208-D212 WeakPolarHBondContact CG-OD2 3.38Å; K208-D212 VanDerWaalsContact O-CB 3.3Å; K208-D212 WeakPolarHBondContact O-CB 3.47Å; K208-D212 PolarHBondContact O-N 3.31Å
209	K	88.6	Confident	84.1	Confident	89 Å²	89	45 Å²	45	39%	0.387	25%	0.245	S	C	.	.	H	α-helix	trans	-60.2	-43	-179.6	-171	178.5	-173.8	178.1	0	112.7	P205 V207 W213 I303 E306	P205-K209 PolarHBondContact O-N 3.18Å; V207-K209 VanDerWaalsContact C-N 3.34Å; V207-K209 PolarHBondContact O-N 3.43Å; K209-W213 PolarHBondContact O-N 3.45Å; K209-W213 VanDerWaalsContact O-N 3.13Å; K209-I303 HydrophobicContact CD-CG1 4.5Å; K209-E306 VanDerWaalsContact NZ-CD 3.35Å; K209-E306 IonicContact NZ-OE1 2.56Å; K209-E306 PolarHBondContact NZ-OE1 3.13Å; K209-E306 IonicContact NZ-OE2 2.9Å; K209-E306 PolarHBondContact NZ-OE2 3.35Å
210	K	88.4	Confident	84.2	Confident	3 Å²	3	46 Å²	46	1%	0.013	25%	0.25	C	C	.	.	H	α-helix	trans	-66	-46.8	175.1	-78.5	-175.7	171.8	-173.5	0	111.7	F137 V207 K208 W213 A214 F239 I303 E304 F307	F137-K210 HydrophobicContact CD2-CD 4.19Å; F137-K210 HydrophobicContact CE1-CD 4.28Å; F137-K210 HydrophobicContact CE2-CB 3.92Å; F137-K210 HydrophobicContact CE2-CD 3.26Å; F137-K210 HydrophobicContact CE2-CG 4.25Å; F137-K210 HydrophobicContact CZ-CD 3.33Å; V207-K210 PolarHBondContact O-N 3.34Å; K208-K210 PolarHBondContact O-N 3.49Å; K210-W213 PolarHBondContact O-N 3.22Å; K210-A214 PolarHBondContact O-N 3.47Å; K210-F239 HydrophobicContact CB-CE2 4.5Å; K210-F239 PolarHBondContact NZ-O 2.98Å; K210-I303 HydrophobicContact CB-CG2 4.45Å; K210-I303 HydrophobicContact CD-CG2 4.49Å; K210-I303 HydrophobicContact CG-CG2 3.4Å; K210-I303 VanDerWaalsContact CG-CG2 3.4Å; K210-E304 WeakPolarHBondContact CE-OE2 3.31Å; K210-E304 IonicContact NZ-OE1 2.75Å; K210-E304 IonicContact NZ-OE2 2.69Å; K210-E304 PolarHBondContact NZ-OE2 2.95Å; K210-F307 HydrophobicContact CD-CD2 4.48Å; K210-F307 HydrophobicContact CD-CG 4.37Å
211	A	88	Confident	84.3	Confident	3 Å²	3	51.1 Å²	51.1	3%	0.025	27%	0.269	C	S	.	.	H	α-helix	trans	-59.6	-48.3	177.9	0	0	0	0	0	111.6	I144 I201 V207 K208 W213 A214 I215	I144-A211 HydrophobicContact CD1-CB 3.61Å; I201-A211 HydrophobicContact CG1-CB 4.36Å; I201-A211 HydrophobicContact CG2-CB 4.23Å; V207-A211 WeakPolarHBondContact O-CB 3.12Å; V207-A211 PolarHBondContact O-N 3.4Å; K208-A211 PolarHBondContact O-N 3.02Å; A211-W213 VanDerWaalsContact C-N 3.3Å; A211-W213 PolarHBondContact O-N 2.94Å; A211-A214 PolarHBondContact O-N 2.91Å; A211-I215 HydrophobicContact CB-CD1 4.46Å; A211-I215 WeakPolarHBondContact O-CB 3.01Å; A211-I215 WeakPolarHBondContact O-CD1 3.07Å; A211-I215 WeakPolarHBondContact O-CG1 3.45Å; A211-I215 PolarHBondContact O-N 2.87Å
212	D	90.6	Very high	84.8	Confident	81 Å²	81	55.9 Å²	55.9	43%	0.433	30%	0.295	S	S	.	.	H	α-helix	trans	-60.5	-39.7	178.4	-72.8	-12.8	0	0	0	111.2	K208 N216	K208-D212 WeakPolarHBondContact CE-OD2 3.35Å; K208-D212 WeakPolarHBondContact CG-OD2 3.38Å; K208-D212 VanDerWaalsContact O-CB 3.3Å; K208-D212 WeakPolarHBondContact O-CB 3.47Å; K208-D212 PolarHBondContact O-N 3.31Å; D212-N216 VanDerWaalsContact O-CB 3.23Å; D212-N216 WeakPolarHBondContact O-CB 3.3Å; D212-N216 PolarHBondContact O-N 3.48Å
213	W	92.8	Very high	85.3	Confident	28 Å²	28	50.6 Å²	50.6	11%	0.106	27%	0.271	C	S	.	.	H	α-helix	trans	-63	-47.5	174.8	-174.1	97.4	0	0	0	111.7	K209 K210 A211 N216 W217 A231 A234 V235 F239 I296 A300 I303	K209-W213 PolarHBondContact O-N 3.45Å; K209-W213 VanDerWaalsContact O-N 3.13Å; K210-W213 PolarHBondContact O-N 3.22Å; A211-W213 VanDerWaalsContact C-N 3.3Å; A211-W213 PolarHBondContact O-N 2.94Å; W213-N216 PolarHBondContact O-N 2.9Å; W213-W217 AromaticContact CD2-CD1 3.68Å; W213-W217 AromaticContact CD2-NE1 3.64Å; W213-W217 AromaticContact CE2-CD1 3.76Å; W213-W217 AromaticContact CE2-NE1 3.22Å; W213-W217 AromaticContact CE3-CD1 3.6Å; W213-W217 AromaticContact CE3-NE1 3.96Å; W213-W217 AromaticContact CH2-CD1 3.76Å; W213-W217 AromaticContact CH2-NE1 3.62Å; W213-W217 AromaticContact CZ2-CD1 3.82Å; W213-W217 AromaticContact CZ2-NE1 3.24Å; W213-W217 AromaticContact CZ3-CD1 3.64Å; W213-W217 AromaticContact CZ3-NE1 3.96Å; W213-W217 AromaticContact NE1-NE1 3.68Å; W213-W217 PolarHBondContact O-N 3.23Å; W213-A231 HydrophobicContact CH2-CB 3.98Å; W213-A231 HydrophobicContact CZ3-CB 4.39Å; W213-A234 HydrophobicContact CH2-CB 4.04Å; W213-V235 HydrophobicContact CE3-CG2 4.38Å; W213-V235 HydrophobicContact CZ3-CG2 3.76Å; W213-F239 HydrophobicContact CB-CZ 4.36Å; W213-F239 AromaticContact CD2-CE2 3.95Å; W213-F239 HydrophobicContact CD2-CE2 3.95Å; W213-F239 AromaticContact CD2-CZ 3.64Å; W213-F239 HydrophobicContact CD2-CZ 3.64Å; W213-F239 HydrophobicContact CE3-CD2 4.42Å; W213-F239 AromaticContact CE3-CE2 3.27Å; W213-F239 HydrophobicContact CE3-CE2 3.27Å; W213-F239 AromaticContact CE3-CZ 3.43Å; W213-F239 HydrophobicContact CE3-CZ 3.43Å; W213-F239 VanDerWaalsContact CE3-CZ 3.43Å; W213-F239 HydrophobicContact CG-CZ 4.08Å; W213-F239 HydrophobicContact CH2-CZ 4.49Å; W213-F239 AromaticContact CZ3-CE2 3.71Å; W213-F239 HydrophobicContact CZ3-CE2 3.71Å; W213-F239 AromaticContact CZ3-CZ 3.9Å; W213-F239 HydrophobicContact CZ3-CZ 3.9Å; W213-I296 HydrophobicContact CH2-CG2 4.06Å; W213-I296 HydrophobicContact CZ2-CG2 3.86Å; W213-A300 HydrophobicContact CH2-CB 4.31Å; W213-A300 HydrophobicContact CZ2-CB 4.18Å; W213-I303 HydrophobicContact CB-CD1 3.98Å; W213-I303 VanDerWaalsContact CD1-CD1 3.48Å; W213-I303 HydrophobicContact CG-CD1 3.77Å
214	A	89.6	Confident	86	Confident	12 Å²	12	50.1 Å²	50.1	10%	0.099	27%	0.27	C	S	.	.	H	α-helix	trans	-64.5	-50.4	179.6	0	0	0	0	0	111.4	I144 K210 A211 N216 W217 I218 V235	I144-A214 HydrophobicContact CG2-CB 4.11Å; K210-A214 PolarHBondContact O-N 3.47Å; A211-A214 PolarHBondContact O-N 2.91Å; A214-N216 PolarHBondContact O-N 3.27Å; A214-W217 PolarHBondContact O-N 3.42Å; A214-I218 WeakPolarHBondContact O-CG1 3.11Å; A214-I218 PolarHBondContact O-N 3.37Å; A214-V235 HydrophobicContact CB-CG2 4.21Å
215	I	87.6	Confident	86.7	Confident	40 Å²	40	49.8 Å²	49.8	21%	0.205	27%	0.268	C	S	.	.	H	α-helix	trans	-57.3	-39	178.3	-68.3	166	0	0	0	111.1	I144 A211 W217 I218 G219	I144-I215 HydrophobicContact CD1-CD1 4.19Å; I144-I215 HydrophobicContact CD1-CG1 4.33Å; I144-I215 HydrophobicContact CG2-CG1 3.92Å; A211-I215 HydrophobicContact CB-CD1 4.46Å; A211-I215 WeakPolarHBondContact O-CB 3.01Å; A211-I215 WeakPolarHBondContact O-CD1 3.07Å; A211-I215 WeakPolarHBondContact O-CG1 3.45Å; A211-I215 PolarHBondContact O-N 2.87Å; I215-W217 VanDerWaalsContact C-N 3.3Å; I215-W217 PolarHBondContact O-N 2.96Å; I215-I218 PolarHBondContact O-N 3.06Å; I215-G219 PolarHBondContact O-N 3.22Å
216	N	91.3	Very high	87.3	Confident	91 Å²	91	44.8 Å²	44.8	49%	0.487	24%	0.236	S	C	.	.	H	α-helix	trans	-58.6	-41.6	175.6	177.8	67.8	0	0	0	111.7	D212 W213 A214 N220	D212-N216 VanDerWaalsContact O-CB 3.23Å; D212-N216 WeakPolarHBondContact O-CB 3.3Å; D212-N216 PolarHBondContact O-N 3.48Å; W213-N216 PolarHBondContact O-N 2.9Å; A214-N216 PolarHBondContact O-N 3.27Å; N216-N220 WeakPolarHBondContact O-CB 3.31Å; N216-N220 PolarHBondContact O-N 2.86Å
217	W	88.8	Confident	88.3	Confident	41 Å²	41	45.5 Å²	45.5	16%	0.155	24%	0.236	C	C	.	.	H	α-helix	trans	-70.6	-30.8	177.6	-71.3	109.6	0	0	0	113.9	W213 A214 I215 A223 E227 R228 A231 I296	W213-W217 AromaticContact CD2-CD1 3.68Å; W213-W217 AromaticContact CD2-NE1 3.64Å; W213-W217 AromaticContact CE2-CD1 3.76Å; W213-W217 AromaticContact CE2-NE1 3.22Å; W213-W217 AromaticContact CE3-CD1 3.6Å; W213-W217 AromaticContact CE3-NE1 3.96Å; W213-W217 AromaticContact CH2-CD1 3.76Å; W213-W217 AromaticContact CH2-NE1 3.62Å; W213-W217 AromaticContact CZ2-CD1 3.82Å; W213-W217 AromaticContact CZ2-NE1 3.24Å; W213-W217 AromaticContact CZ3-CD1 3.64Å; W213-W217 AromaticContact CZ3-NE1 3.96Å; W213-W217 AromaticContact NE1-NE1 3.68Å; W213-W217 PolarHBondContact O-N 3.23Å; A214-W217 PolarHBondContact O-N 3.42Å; I215-W217 VanDerWaalsContact C-N 3.3Å; I215-W217 PolarHBondContact O-N 2.96Å; W217-A223 HydrophobicContact CE3-CB 4.19Å; W217-A223 HydrophobicContact CZ3-CB 4.04Å; W217-E227 HydrophobicContact CZ3-CB 4.09Å; W217-R228 WeakPolarHBondContact O-CD 3.44Å; W217-A231 HydrophobicContact CB-CB 3.89Å; W217-A231 HydrophobicContact CD2-CB 3.52Å; W217-A231 HydrophobicContact CE3-CB 4.02Å; W217-A231 HydrophobicContact CG-CB 3.43Å; W217-A231 VanDerWaalsContact CG-CB 3.43Å; W217-I296 HydrophobicContact CH2-CD1 3.67Å; W217-I296 HydrophobicContact CH2-CG1 3.7Å; W217-I296 HydrophobicContact CZ2-CD1 4.08Å; W217-I296 HydrophobicContact CZ2-CG1 3.69Å; W217-I296 HydrophobicContact CZ2-CG2 4.33Å; W217-I296 HydrophobicContact CZ3-CD1 4.23Å
218	I	80.9	Confident	88.9	Confident	10 Å²	10	45.9 Å²	45.9	5%	0.051	24%	0.238	C	C	.	.	H	α-helix	trans	-65.8	-52.7	173.1	-56.4	173.8	0	0	0	109.7	F57 I144 N148 R152 A214 I215	F57-I218 HydrophobicContact CE1-CG2 4.33Å; I144-I218 HydrophobicContact CG2-CD1 3.56Å; I144-I218 WeakPolarHBondContact O-CD1 3.32Å; N148-I218 HydrophobicContact CB-CD1 3.66Å; N148-I218 HydrophobicContact CB-CG1 3.68Å; N148-I218 HydrophobicContact CB-CG2 4.39Å; R152-I218 WeakPolarHBondContact CD-O 3.49Å; R152-I218 HydrophobicContact CG-CG2 4.41Å; R152-I218 PolarHBondContact NH1-O 3.28Å; R152-I218 VanDerWaalsContact NH1-O 3.15Å; A214-I218 WeakPolarHBondContact O-CG1 3.11Å; A214-I218 PolarHBondContact O-N 3.37Å; I215-I218 PolarHBondContact O-N 3.06Å
219	G	80.4	Confident	89.3	Confident	48 Å²	48	40.8 Å²	40.8	50%	0.495	22%	0.216	S	C	.	.	H	α-helix	trans	-78.1	-16.5	-175	0	0	0	0	0	115.2	I215 R221	I215-G219 PolarHBondContact O-N 3.22Å; G219-R221 PolarHBondContact O-N 3.5Å
220	N	85.4	Confident	89.8	Confident	45 Å²	45	36.6 Å²	36.6	24%	0.241	20%	0.197	C	C	.	.			trans	-72.5	100.6	-176.6	-173.7	-4.9	0	0	0	111.5	N216 N222 A223	N216-N220 WeakPolarHBondContact O-CB 3.31Å; N216-N220 PolarHBondContact O-N 2.86Å; N220-N222 VanDerWaalsContact C-N 3.27Å; N220-N222 PolarHBondContact O-N 3Å; N220-N222 WeakPolarHBondContact OD1-CA 3.47Å; N220-N222 WeakPolarHBondContact OD1-CB 3.21Å; N220-N222 PolarHBondContact OD1-N 3.29Å; N220-A223 HydrophobicContact CB-CB 4.23Å; N220-A223 PolarHBondContact O-N 3.11Å; N220-A223 PolarHBondContact OD1-N 3.21Å
221	R	80	Confident	90.1	Very high	108 Å²	108	36.5 Å²	36.5	41%	0.408	20%	0.197	S	C	.	.	T	Hydrogen-bonded Turn	trans	-72	-17	176.7	-62.4	-172.6	179.2	-150.3	1.7	113.9	A60 A61 N63 G219	A60-R221 PolarHBondContact O-NH2 3.44Å; A60-R221 VanDerWaalsContact O-NH2 3.11Å; A61-R221 PolarHBondContact O-NH2 3.02Å; N63-R221 PolarHBondContact O-NH1 2.78Å; G219-R221 PolarHBondContact O-N 3.5Å
222	N	87.2	Confident	90.4	Very high	155 Å²	155	36.8 Å²	36.8	83%	0.829	20%	0.198	S	C	*	.	T	Hydrogen-bonded Turn	trans	-89.6	-15.5	179.4	-62.5	-28	0	0	0	112.7	N220	N220-N222 VanDerWaalsContact C-N 3.27Å; N220-N222 PolarHBondContact O-N 3Å; N220-N222 WeakPolarHBondContact OD1-CA 3.47Å; N220-N222 WeakPolarHBondContact OD1-CB 3.21Å; N220-N222 PolarHBondContact OD1-N 3.29Å
223	A	89.8	Confident	90.7	Very high	5 Å²	5	32.9 Å²	32.9	4%	0.041	18%	0.177	C	C	.	.	S	Bend	trans	-70.4	139.6	172.5	0	0	0	0	0	109.9	W217 N220 E227 R228	W217-A223 HydrophobicContact CE3-CB 4.19Å; W217-A223 HydrophobicContact CZ3-CB 4.04Å; N220-A223 HydrophobicContact CB-CB 4.23Å; N220-A223 PolarHBondContact O-N 3.11Å; N220-A223 PolarHBondContact OD1-N 3.21Å; A223-E227 WeakPolarHBondContact CA-OE2 3.36Å; A223-E227 HydrophobicContact CB-CB 4.42Å; A223-R228 HydrophobicContact CB-CG 4.06Å; A223-R228 PolarHBondContact O-NH1 3.35Å
224	S	92.6	Very high	90.8	Very high	37 Å²	37	31.6 Å²	31.6	26%	0.259	17%	0.172	S	C	.	.			trans	-69.1	159.8	168.7	60.8	0	0	0	0	111	G226 E227 R228	S224-G226 PolarHBondContact O-N 2.92Å; S224-E227 PolarHBondContact N-OE2 3.37Å; S224-E227 PolarHBondContact O-N 2.83Å; S224-E227 VanDerWaalsContact OG-CG 3.31Å; S224-E227 WeakPolarHBondContact OG-CG 3.41Å; S224-E227 PolarHBondContact OG-N 3.27Å; S224-E227 PolarHBondContact OG-OE2 3.39Å; S224-R228 PolarHBondContact O-N 3.2Å; S224-R228 VanDerWaalsContact O-N 3.12Å
225	Y	92.6	Very high	91	Very high	3 Å²	3	31.6 Å²	31.6	1%	0.012	17%	0.171	C	C	.	.	H	α-helix	trans	-55	-40.6	171	175.8	-97.5	0	0	0	111.9	L76 L77 F153 E156 V157 E227 R228 V229 L284	L76-Y225 HydrophobicContact CD1-CE1 4.3Å; L77-Y225 HydrophobicContact CD1-CD1 4.31Å; L77-Y225 HydrophobicContact CD1-CG 4.02Å; L77-Y225 HydrophobicContact CD2-CD1 4.21Å; L77-Y225 HydrophobicContact CD2-CD2 3.99Å; L77-Y225 HydrophobicContact CD2-CE1 4.36Å; L77-Y225 HydrophobicContact CD2-CE2 4.16Å; L77-Y225 HydrophobicContact CD2-CG 4.02Å; F153-Y225 HydrophobicContact CD1-CD2 4.49Å; F153-Y225 HydrophobicContact CD1-CE2 4.02Å; F153-Y225 HydrophobicContact CE1-CD2 4.45Å; F153-Y225 HydrophobicContact CE1-CE2 4.2Å; E156-Y225 WeakPolarHBondContact OE2-CD2 3.48Å; V157-Y225 HydrophobicContact CG2-CE2 3.82Å; V157-Y225 VanDerWaalsContact CG2-OH 3.28Å; V157-Y225 WeakPolarHBondContact CG2-OH 3.47Å; Y225-E227 PolarHBondContact O-N 3.23Å; Y225-R228 PolarHBondContact O-N 3.31Å; Y225-V229 HydrophobicContact CD1-CG2 3.87Å; Y225-V229 HydrophobicContact CD2-CG2 4.34Å; Y225-V229 HydrophobicContact CE1-CG2 3.39Å; Y225-V229 HydrophobicContact CE2-CG2 3.91Å; Y225-V229 HydrophobicContact CG-CG2 4.33Å; Y225-V229 VanDerWaalsContact CZ-CG2 3.4Å; Y225-V229 WeakPolarHBondContact O-CG2 3.32Å; Y225-V229 PolarHBondContact O-N 3.16Å; Y225-L284 HydrophobicContact CD1-CD1 4.1Å; Y225-L284 HydrophobicContact CD1-CD2 3.55Å; Y225-L284 HydrophobicContact CD1-CG 4.34Å; Y225-L284 HydrophobicContact CE1-CD1 4.33Å; Y225-L284 HydrophobicContact CE1-CD2 3.82Å; Y225-L284 HydrophobicContact CE1-CG 4.39Å
226	G	95.1	Very high	91.1	Very high	4 Å²	4	29.9 Å²	29.9	4%	0.041	16%	0.162	C	C	.	.	H	α-helix	trans	-62.6	-40.7	179.2	0	0	0	0	0	114.2	S224 V229 V230 L284	S224-G226 PolarHBondContact O-N 2.92Å; G226-V229 PolarHBondContact O-N 3.05Å; G226-V230 WeakPolarHBondContact O-CG2 2.9Å; G226-V230 PolarHBondContact O-N 3.33Å; G226-L284 VanDerWaalsContact CA-CD1 3.44Å
227	E	96.1	Very high	91.1	Very high	44 Å²	44	26 Å²	26	21%	0.206	14%	0.144	C	C	.	.	H	α-helix	trans	-65.1	-40.9	173.5	-70.3	163.3	131.8	0	0	111.7	W217 A223 S224 Y225 V230 A231 P288 T292 I296	W217-E227 HydrophobicContact CZ3-CB 4.09Å; A223-E227 WeakPolarHBondContact CA-OE2 3.36Å; A223-E227 HydrophobicContact CB-CB 4.42Å; S224-E227 PolarHBondContact N-OE2 3.37Å; S224-E227 PolarHBondContact O-N 2.83Å; S224-E227 VanDerWaalsContact OG-CG 3.31Å; S224-E227 WeakPolarHBondContact OG-CG 3.41Å; S224-E227 PolarHBondContact OG-N 3.27Å; S224-E227 PolarHBondContact OG-OE2 3.39Å; Y225-E227 PolarHBondContact O-N 3.23Å; E227-V230 PolarHBondContact O-N 3.15Å; E227-A231 PolarHBondContact O-N 3.46Å; E227-P288 HydrophobicContact CG-CB 3.88Å; E227-P288 HydrophobicContact CG-CG 4.41Å; E227-T292 HydrophobicContact CG-CG2 3.93Å; E227-T292 WeakPolarHBondContact OE1-CG2 3.48Å; E227-I296 HydrophobicContact CB-CD1 4.2Å; E227-I296 HydrophobicContact CG-CD1 4.44Å
228	R	94.7	Very high	91.3	Very high	10 Å²	10	24.1 Å²	24.1	4%	0.038	14%	0.137	C	C	.	.	H	α-helix	trans	-64.5	-39.1	176.6	-69.8	-166.9	-67.2	-87.8	-5.9	112.4	F153 E156 W217 A223 S224 Y225 V230 A231 F232	F153-R228 HydrophobicContact CE1-CB 3.98Å; F153-R228 HydrophobicContact CZ-CB 4.22Å; E156-R228 IonicContact OE1-CZ 3.62Å; E156-R228 IonicContact OE1-NH2 2.76Å; E156-R228 IonicContact OE2-CZ 3.36Å; E156-R228 IonicContact OE2-NE 3.53Å; E156-R228 IonicContact OE2-NH2 3.96Å; E156-R228 PolarHBondContact OE2-NH2 3.42Å; W217-R228 WeakPolarHBondContact O-CD 3.44Å; A223-R228 HydrophobicContact CB-CG 4.06Å; A223-R228 PolarHBondContact O-NH1 3.35Å; S224-R228 PolarHBondContact O-N 3.2Å; S224-R228 VanDerWaalsContact O-N 3.12Å; Y225-R228 PolarHBondContact O-N 3.31Å; R228-V230 VanDerWaalsContact C-N 3.33Å; R228-V230 PolarHBondContact O-N 2.69Å; R228-A231 PolarHBondContact O-N 2.72Å; R228-F232 VanDerWaalsContact O-CB 3.31Å; R228-F232 WeakPolarHBondContact O-CB 3.39Å; R228-F232 PolarHBondContact O-N 2.94Å
229	V	96.1	Very high	91.9	Very high	0 Å²	0	23.8 Å²	23.8	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-61.8	-41.9	175.2	169.8	0	0	0	0	111	F153 Y225 G226 F232 A233 A277 F281	F153-V229 HydrophobicContact CZ-CG2 4.42Å; Y225-V229 HydrophobicContact CD1-CG2 3.87Å; Y225-V229 HydrophobicContact CD2-CG2 4.34Å; Y225-V229 HydrophobicContact CE1-CG2 3.39Å; Y225-V229 HydrophobicContact CE2-CG2 3.91Å; Y225-V229 HydrophobicContact CG-CG2 4.33Å; Y225-V229 VanDerWaalsContact CZ-CG2 3.4Å; Y225-V229 WeakPolarHBondContact O-CG2 3.32Å; Y225-V229 PolarHBondContact O-N 3.16Å; G226-V229 PolarHBondContact O-N 3.05Å; V229-F232 PolarHBondContact O-N 3.4Å; V229-A233 WeakPolarHBondContact O-CB 3.43Å; V229-A233 PolarHBondContact O-N 3.11Å; V229-A277 HydrophobicContact CG1-CB 4.36Å; V229-A277 WeakPolarHBondContact CG1-O 3.5Å; V229-F281 HydrophobicContact CG1-CB 3.94Å; V229-F281 HydrophobicContact CG1-CD2 4.33Å
230	V	97.3	Very high	92.2	Very high	0 Å²	0	21.6 Å²	21.6	0%	0	11%	0.112	C	C	.	.	H	α-helix	trans	-65.3	-44.2	175.7	172.7	0	0	0	0	111.2	G226 E227 R228 F232 A233 A234 F281 V293 I296 I297 L339	G226-V230 WeakPolarHBondContact O-CG2 2.9Å; G226-V230 PolarHBondContact O-N 3.33Å; E227-V230 PolarHBondContact O-N 3.15Å; R228-V230 VanDerWaalsContact C-N 3.33Å; R228-V230 PolarHBondContact O-N 2.69Å; V230-F232 VanDerWaalsContact C-N 3.31Å; V230-F232 PolarHBondContact O-N 3.16Å; V230-A233 PolarHBondContact O-N 3.46Å; V230-A234 PolarHBondContact O-N 3.23Å; V230-F281 HydrophobicContact CG2-CD2 3.74Å; V230-F281 HydrophobicContact CG2-CE2 3.43Å; V230-F281 VanDerWaalsContact CG2-CE2 3.43Å; V230-F281 HydrophobicContact CG2-CZ 4.17Å; V230-V293 HydrophobicContact CG1-CG1 3.89Å; V230-V293 HydrophobicContact CG2-CG1 4.3Å; V230-V293 HydrophobicContact CG2-CG2 4.11Å; V230-I296 HydrophobicContact CB-CD1 4.38Å; V230-I296 HydrophobicContact CG1-CB 4.11Å; V230-I296 HydrophobicContact CG1-CD1 4.18Å; V230-I296 HydrophobicContact CG1-CG2 3.95Å; V230-I297 HydrophobicContact CG1-CD1 4.11Å; V230-I297 HydrophobicContact CG1-CG1 4.37Å; V230-L339 HydrophobicContact CG1-CD1 4.35Å; V230-L339 HydrophobicContact CG2-CD1 4.36Å
231	A	96.1	Very high	92.5	Very high	2 Å²	2	19.8 Å²	19.8	2%	0.017	10%	0.103	C	C	.	.	H	α-helix	trans	-61.7	-41.7	176.9	0	0	0	0	0	111.5	W213 W217 E227 R228 A234 V235 I296	W213-A231 HydrophobicContact CH2-CB 3.98Å; W213-A231 HydrophobicContact CZ3-CB 4.39Å; W217-A231 HydrophobicContact CB-CB 3.89Å; W217-A231 HydrophobicContact CD2-CB 3.52Å; W217-A231 HydrophobicContact CE3-CB 4.02Å; W217-A231 HydrophobicContact CG-CB 3.43Å; W217-A231 VanDerWaalsContact CG-CB 3.43Å; E227-A231 PolarHBondContact O-N 3.46Å; R228-A231 PolarHBondContact O-N 2.72Å; A231-A234 WeakPolarHBondContact O-CB 3.48Å; A231-A234 PolarHBondContact O-N 3.35Å; A231-V235 PolarHBondContact O-N 3.01Å; A231-I296 HydrophobicContact CB-CG2 4.09Å
232	F	94.4	Very high	93.2	Very high	8 Å²	8	14.6 Å²	14.6	4%	0.035	8%	0.084	C	C	.	.	H	α-helix	trans	-63.6	-46.6	175.9	-173.3	-105.8	0	0	0	112.3	V145 N148 L149 F153 R228 V229 V230 A234 V235 E236 A277	V145-F232 HydrophobicContact CG1-CE2 3.97Å; V145-F232 HydrophobicContact CG1-CZ 4.22Å; N148-F232 WeakPolarHBondContact ND2-CD2 3.39Å; L149-F232 HydrophobicContact CD1-CZ 4.35Å; L149-F232 HydrophobicContact CD2-CE1 4.26Å; L149-F232 HydrophobicContact CD2-CE2 4.1Å; L149-F232 HydrophobicContact CD2-CZ 3.58Å; L149-F232 HydrophobicContact CG-CE2 4.21Å; L149-F232 HydrophobicContact CG-CZ 4Å; F153-F232 HydrophobicContact CD2-CD1 4.39Å; F153-F232 HydrophobicContact CD2-CG 4.36Å; F153-F232 HydrophobicContact CE2-CB 3.61Å; F153-F232 AromaticContact CE2-CD1 3.66Å; F153-F232 HydrophobicContact CE2-CD1 3.66Å; F153-F232 AromaticContact CE2-CD2 3.78Å; F153-F232 HydrophobicContact CE2-CD2 3.78Å; F153-F232 HydrophobicContact CE2-CE1 4.23Å; F153-F232 HydrophobicContact CE2-CE2 4.32Å; F153-F232 AromaticContact CE2-CG 3.4Å; F153-F232 HydrophobicContact CE2-CG 3.4Å; F153-F232 VanDerWaalsContact CE2-CG 3.4Å; F153-F232 HydrophobicContact CZ-CB 3.8Å; F153-F232 HydrophobicContact CZ-CD2 4.49Å; F153-F232 HydrophobicContact CZ-CG 4.1Å; R228-F232 VanDerWaalsContact O-CB 3.31Å; R228-F232 WeakPolarHBondContact O-CB 3.39Å; R228-F232 PolarHBondContact O-N 2.94Å; V229-F232 PolarHBondContact O-N 3.4Å; V230-F232 VanDerWaalsContact C-N 3.31Å; V230-F232 PolarHBondContact O-N 3.16Å; F232-A234 PolarHBondContact O-N 3Å; F232-V235 WeakPolarHBondContact O-CB 3.5Å; F232-V235 PolarHBondContact O-N 3.24Å; F232-E236 HydrophobicContact CD1-CG 4.04Å; F232-E236 HydrophobicContact CE1-CG 3.75Å; F232-E236 HydrophobicContact CE2-CG 4.41Å; F232-E236 WeakPolarHBondContact CE2-OE1 3.49Å; F232-E236 HydrophobicContact CG-CG 4.49Å; F232-E236 HydrophobicContact CZ-CG 3.94Å; F232-E236 WeakPolarHBondContact CZ-OE1 3.5Å; F232-E236 WeakPolarHBondContact O-CG 3.2Å; F232-E236 PolarHBondContact O-N 3.41Å; F232-A277 HydrophobicContact CD1-CB 4.2Å
233	A	95.3	Very high	93.5	Very high	0 Å²	0	7.2 Å²	7.2	0%	0	4%	0.044	C	C	.	.	H	α-helix	trans	-59.1	-30.7	174.2	0	0	0	0	0	112.4	V229 V230 G237 A277 L335	V229-A233 WeakPolarHBondContact O-CB 3.43Å; V229-A233 PolarHBondContact O-N 3.11Å; V230-A233 PolarHBondContact O-N 3.46Å; A233-G237 WeakPolarHBondContact O-CA 3.33Å; A233-G237 PolarHBondContact O-N 3.11Å; A233-A277 HydrophobicContact CB-CB 3.77Å; A233-L335 HydrophobicContact CB-CD1 4.08Å; A233-L335 HydrophobicContact CB-CD2 4.38Å
234	A	95.9	Very high	93.8	Very high	0 Å²	0	7.7 Å²	7.7	0%	0	5%	0.045	C	C	.	.	H	α-helix	trans	-73.5	-32.8	173.7	0	0	0	0	0	113.1	W213 V230 A231 F232 I238 F239 I297 A300	W213-A234 HydrophobicContact CH2-CB 4.04Å; V230-A234 PolarHBondContact O-N 3.23Å; A231-A234 WeakPolarHBondContact O-CB 3.48Å; A231-A234 PolarHBondContact O-N 3.35Å; F232-A234 PolarHBondContact O-N 3Å; A234-I238 HydrophobicContact CB-CD1 4.28Å; A234-I238 WeakPolarHBondContact O-CA 3.44Å; A234-I238 VanDerWaalsContact O-CB 3.26Å; A234-I238 WeakPolarHBondContact O-CB 3.26Å; A234-I238 PolarHBondContact O-N 3.49Å; A234-F239 PolarHBondContact O-N 3.4Å; A234-F239 VanDerWaalsContact O-N 3.09Å; A234-I297 HydrophobicContact CB-CD1 3.95Å; A234-A300 HydrophobicContact CB-CB 3.91Å
235	V	93	Very high	94	Very high	13 Å²	13	5.9 Å²	5.9	8%	0.079	3%	0.033	C	C	.	.	I	π-helix	trans	-63.5	-57.5	171.9	177.5	0	0	0	0	109.7	V145 W213 A214 A231 F232 G237 F239 F240	V145-V235 HydrophobicContact CG2-CG1 3.78Å; W213-V235 HydrophobicContact CE3-CG2 4.38Å; W213-V235 HydrophobicContact CZ3-CG2 3.76Å; A214-V235 HydrophobicContact CB-CG2 4.21Å; A231-V235 PolarHBondContact O-N 3.01Å; F232-V235 WeakPolarHBondContact O-CB 3.5Å; F232-V235 PolarHBondContact O-N 3.24Å; V235-G237 PolarHBondContact O-N 2.93Å; V235-F239 HydrophobicContact CB-CD2 4.36Å; V235-F239 HydrophobicContact CG1-CD2 4.39Å; V235-F239 HydrophobicContact CG2-CD2 4.02Å; V235-F239 HydrophobicContact CG2-CE2 4.28Å; V235-F239 WeakPolarHBondContact O-CB 3.31Å; V235-F239 PolarHBondContact O-N 2.88Å; V235-F240 HydrophobicContact CG1-CE2 4.28Å; V235-F240 WeakPolarHBondContact O-CD2 3.42Å
236	E	90.6	Very high	94.2	Very high	3 Å²	3	5.8 Å²	5.8	1%	0.014	3%	0.032	C	C	.	.	I	π-helix	trans	-62.6	-41.3	-177.6	-58.2	-84.5	154.2	0	0	111.7	V145 Q169 F232 H273 C274	V145-E236 WeakPolarHBondContact CG1-OE1 3.46Å; Q169-E236 PolarHBondContact NE2-OE1 2.92Å; F232-E236 HydrophobicContact CD1-CG 4.04Å; F232-E236 HydrophobicContact CE1-CG 3.75Å; F232-E236 HydrophobicContact CE2-CG 4.41Å; F232-E236 WeakPolarHBondContact CE2-OE1 3.49Å; F232-E236 HydrophobicContact CG-CG 4.49Å; F232-E236 HydrophobicContact CZ-CG 3.94Å; F232-E236 WeakPolarHBondContact CZ-OE1 3.5Å; F232-E236 WeakPolarHBondContact O-CG 3.2Å; F232-E236 PolarHBondContact O-N 3.41Å; E236-H273 HydrophobicContact CG-CB 4.42Å; E236-H273 WeakPolarHBondContact OE2-CB 3.34Å; E236-H273 IonicContact OE2-CG 3.91Å; E236-H273 IonicContact OE2-ND1 3.71Å; E236-H273 PolarHBondContact OE2-ND1 3.23Å; E236-H273 VanDerWaalsContact OE2-ND1 3.11Å; E236-C274 HydrophobicContact CB-CB 4.22Å
237	G	90.1	Very high	94.2	Very high	11 Å²	11	5.9 Å²	5.9	11%	0.113	3%	0.032	C	C	.	.	I	π-helix	trans	-95.7	-29.1	-170.2	0	0	0	0	0	116.1	A233 V235 S241 V331	A233-G237 WeakPolarHBondContact O-CA 3.33Å; A233-G237 PolarHBondContact O-N 3.11Å; V235-G237 PolarHBondContact O-N 2.93Å; G237-S241 WeakPolarHBondContact O-CB 3.44Å; G237-V331 WeakPolarHBondContact O-CG1 3.46Å
238	I	94.9	Very high	94.2	Very high	0 Å²	0	4.2 Å²	4.2	0%	0	2%	0.024	C	C	.	.	I	π-helix	trans	-111.9	-50.6	-174.2	-60.6	174.7	0	0	0	111.3	A234 F240 S241 I297 A300 V301 E304 I328 A332 L335	A234-I238 HydrophobicContact CB-CD1 4.28Å; A234-I238 WeakPolarHBondContact O-CA 3.44Å; A234-I238 VanDerWaalsContact O-CB 3.26Å; A234-I238 WeakPolarHBondContact O-CB 3.26Å; A234-I238 PolarHBondContact O-N 3.49Å; I238-F240 PolarHBondContact O-N 3.2Å; I238-F240 VanDerWaalsContact O-N 3.12Å; I238-S241 WeakPolarHBondContact O-CB 3.27Å; I238-S241 PolarHBondContact O-N 2.88Å; I238-S241 PolarHBondContact O-OG 3.06Å; I238-I297 HydrophobicContact CD1-CD1 4.09Å; I238-I297 HydrophobicContact CD1-CG2 3.85Å; I238-A300 HydrophobicContact CD1-CB 4.38Å; I238-A300 HydrophobicContact CG2-CB 4.36Å; I238-V301 HydrophobicContact CD1-CG2 4.29Å; I238-V301 HydrophobicContact CG2-CG2 4.3Å; I238-E304 HydrophobicContact CG2-CB 4.18Å; I238-E304 HydrophobicContact CG2-CG 4.39Å; I238-I328 HydrophobicContact CG2-CG2 4.13Å; I238-A332 HydrophobicContact CD1-CB 3.91Å; I238-L335 HydrophobicContact CD1-CD2 3.93Å; I238-L335 HydrophobicContact CG1-CD2 4.08Å
239	F	92.1	Very high	94.3	Very high	4 Å²	4	6.8 Å²	6.8	2%	0.018	3%	0.033	C	C	.	.	I	π-helix	trans	-64.9	-18.4	-172.8	-77.6	-10.7	0	0	0	115.5	K210 W213 A234 V235 A300 I303 E304	K210-F239 HydrophobicContact CB-CE2 4.5Å; K210-F239 PolarHBondContact NZ-O 2.98Å; W213-F239 HydrophobicContact CB-CZ 4.36Å; W213-F239 AromaticContact CD2-CE2 3.95Å; W213-F239 HydrophobicContact CD2-CE2 3.95Å; W213-F239 AromaticContact CD2-CZ 3.64Å; W213-F239 HydrophobicContact CD2-CZ 3.64Å; W213-F239 HydrophobicContact CE3-CD2 4.42Å; W213-F239 AromaticContact CE3-CE2 3.27Å; W213-F239 HydrophobicContact CE3-CE2 3.27Å; W213-F239 AromaticContact CE3-CZ 3.43Å; W213-F239 HydrophobicContact CE3-CZ 3.43Å; W213-F239 VanDerWaalsContact CE3-CZ 3.43Å; W213-F239 HydrophobicContact CG-CZ 4.08Å; W213-F239 HydrophobicContact CH2-CZ 4.49Å; W213-F239 AromaticContact CZ3-CE2 3.71Å; W213-F239 HydrophobicContact CZ3-CE2 3.71Å; W213-F239 AromaticContact CZ3-CZ 3.9Å; W213-F239 HydrophobicContact CZ3-CZ 3.9Å; A234-F239 PolarHBondContact O-N 3.4Å; A234-F239 VanDerWaalsContact O-N 3.09Å; V235-F239 HydrophobicContact CB-CD2 4.36Å; V235-F239 HydrophobicContact CG1-CD2 4.39Å; V235-F239 HydrophobicContact CG2-CD2 4.02Å; V235-F239 HydrophobicContact CG2-CE2 4.28Å; V235-F239 WeakPolarHBondContact O-CB 3.31Å; V235-F239 PolarHBondContact O-N 2.88Å; F239-A300 HydrophobicContact CD1-CB 4.29Å; F239-A300 HydrophobicContact CE1-CB 3.74Å; F239-A300 WeakPolarHBondContact CE1-O 3.45Å; F239-A300 HydrophobicContact CZ-CB 4.31Å; F239-I303 HydrophobicContact CE1-CB 4.08Å; F239-I303 HydrophobicContact CE1-CG2 4.05Å; F239-I303 HydrophobicContact CZ-CB 4.49Å; F239-I303 HydrophobicContact CZ-CD1 4.26Å; F239-I303 HydrophobicContact CZ-CG2 4.29Å; F239-E304 WeakPolarHBondContact CA-OE2 3.33Å; F239-E304 VanDerWaalsContact O-OE2 3.05Å
240	F	86.9	Confident	94.2	Very high	1 Å²	1	6.8 Å²	6.8	0%	0.004	3%	0.034	C	C	.	.	T	Hydrogen-bonded Turn	trans	-103.4	-15.3	174.7	-60.8	-47.6	0	0	0	113.5	F137 F138 V235 I238 G242 S243 F244	F137-F240 HydrophobicContact CD1-CE1 4.5Å; F137-F240 AromaticContact CE1-CD1 3.63Å; F137-F240 HydrophobicContact CE1-CD1 3.63Å; F137-F240 AromaticContact CE1-CE1 3.63Å; F137-F240 HydrophobicContact CE1-CE1 3.63Å; F137-F240 HydrophobicContact CZ-CD1 4.17Å; F137-F240 AromaticContact CZ-CE1 3.88Å; F137-F240 HydrophobicContact CZ-CE1 3.88Å; F138-F240 AromaticContact CD1-CD1 3.53Å; F138-F240 HydrophobicContact CD1-CD1 3.53Å; F138-F240 AromaticContact CD1-CE1 3.67Å; F138-F240 HydrophobicContact CD1-CE1 3.67Å; F138-F240 HydrophobicContact CD1-CG 4.39Å; F138-F240 HydrophobicContact CE1-CB 3.98Å; F138-F240 AromaticContact CE1-CD1 3.3Å; F138-F240 HydrophobicContact CE1-CD1 3.3Å; F138-F240 AromaticContact CE1-CE1 3.96Å; F138-F240 HydrophobicContact CE1-CE1 3.96Å; F138-F240 AromaticContact CE1-CG 3.88Å; F138-F240 HydrophobicContact CE1-CG 3.88Å; V235-F240 HydrophobicContact CG1-CE2 4.28Å; V235-F240 WeakPolarHBondContact O-CD2 3.42Å; I238-F240 PolarHBondContact O-N 3.2Å; I238-F240 VanDerWaalsContact O-N 3.12Å; F240-G242 PolarHBondContact O-N 3.01Å; F240-S243 PolarHBondContact O-N 3.03Å; F240-F244 HydrophobicContact CB-CD2 3.97Å; F240-F244 HydrophobicContact CB-CE1 4.38Å; F240-F244 HydrophobicContact CB-CE2 3.43Å; F240-F244 VanDerWaalsContact CB-CE2 3.43Å; F240-F244 HydrophobicContact CB-CZ 3.67Å; F240-F244 HydrophobicContact CG-CE2 4.42Å; F240-F244 HydrophobicContact CG-CZ 4.31Å; F240-F244 WeakPolarHBondContact O-CD2 3.47Å; F240-F244 WeakPolarHBondContact O-CG 3.36Å; F240-F244 PolarHBondContact O-N 3.06Å
241	S	92	Very high	94.1	Very high	7 Å²	7	9.5 Å²	9.5	5%	0.049	5%	0.045	C	C	.	.	H	α-helix	trans	-58.6	-46.1	-168.4	64.5	0	0	0	0	113.5	G237 I238 F244 A245	G237-S241 WeakPolarHBondContact O-CB 3.44Å; I238-S241 WeakPolarHBondContact O-CB 3.27Å; I238-S241 PolarHBondContact O-N 2.88Å; I238-S241 PolarHBondContact O-OG 3.06Å; S241-F244 PolarHBondContact O-N 3.4Å; S241-A245 PolarHBondContact O-N 3.15Å
242	G	94.1	Very high	94	Very high	0 Å²	0	14.3 Å²	14.3	0%	0	7%	0.066	C	C	.	.	H	α-helix	trans	-75.6	-32	-177.3	0	0	0	0	0	112.7	F240 A245 A246 E304 M324	F240-G242 PolarHBondContact O-N 3.01Å; G242-A245 PolarHBondContact O-N 3.33Å; G242-A246 VanDerWaalsContact O-CB 3.31Å; G242-A246 WeakPolarHBondContact O-CB 3.38Å; G242-A246 PolarHBondContact O-N 3.03Å; G242-E304 PolarHBondContact N-OE1 3.45Å; G242-M324 VanDerWaalsContact O-CE 3.3Å; G242-M324 WeakPolarHBondContact O-CE 3.34Å
243	S	94.9	Very high	94	Very high	0 Å²	0	18.5 Å²	18.5	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-63.7	-43.2	170.8	-65.6	0	0	0	0	111.8	F240 A246 I247	F240-S243 PolarHBondContact O-N 3.03Å; S243-A246 WeakPolarHBondContact O-CB 3.24Å; S243-A246 PolarHBondContact O-N 3Å; S243-I247 PolarHBondContact O-N 3.42Å
244	F	95.3	Very high	94	Very high	14 Å²	14	21.1 Å²	21.1	6%	0.061	11%	0.108	C	C	.	.	H	α-helix	trans	-61.6	-45.5	174	-65.7	-30.7	0	0	0	111.9	F138 F240 S241 A246 I247 F248 N263 I266 E270	F138-F244 HydrophobicContact CE1-CD1 4.21Å; F138-F244 AromaticContact CE1-CE1 3.63Å; F138-F244 HydrophobicContact CE1-CE1 3.63Å; F138-F244 HydrophobicContact CE1-CZ 4.1Å; F138-F244 HydrophobicContact CE2-CE1 4.42Å; F138-F244 AromaticContact CZ-CD1 3.66Å; F138-F244 HydrophobicContact CZ-CD1 3.66Å; F138-F244 AromaticContact CZ-CE1 3.48Å; F138-F244 HydrophobicContact CZ-CE1 3.48Å; F138-F244 VanDerWaalsContact CZ-CE1 3.48Å; F138-F244 HydrophobicContact CZ-CZ 4.36Å; F240-F244 HydrophobicContact CB-CD2 3.97Å; F240-F244 HydrophobicContact CB-CE1 4.38Å; F240-F244 HydrophobicContact CB-CE2 3.43Å; F240-F244 VanDerWaalsContact CB-CE2 3.43Å; F240-F244 HydrophobicContact CB-CZ 3.67Å; F240-F244 HydrophobicContact CG-CE2 4.42Å; F240-F244 HydrophobicContact CG-CZ 4.31Å; F240-F244 WeakPolarHBondContact O-CD2 3.47Å; F240-F244 WeakPolarHBondContact O-CG 3.36Å; F240-F244 PolarHBondContact O-N 3.06Å; S241-F244 PolarHBondContact O-N 3.4Å; F244-A246 VanDerWaalsContact C-N 3.27Å; F244-A246 PolarHBondContact O-N 3.06Å; F244-I247 PolarHBondContact O-N 3.38Å; F244-F248 WeakPolarHBondContact O-CD2 3.4Å; F244-F248 PolarHBondContact O-N 3.3Å; F244-N263 WeakPolarHBondContact CD1-OD1 3.48Å; F244-I266 HydrophobicContact CE1-CG2 4.18Å; F244-I266 HydrophobicContact CZ-CG2 4.06Å; F244-E270 HydrophobicContact CE2-CB 3.95Å; F244-E270 HydrophobicContact CE2-CG 3.78Å; F244-E270 HydrophobicContact CZ-CB 4.3Å; F244-E270 HydrophobicContact CZ-CG 3.63Å
245	A	95.9	Very high	94	Very high	0 Å²	0	22.5 Å²	22.5	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-61.4	-36.8	175.6	0	0	0	0	0	112.4	S241 G242 F248 W249 M324 Y327 F351 M354	S241-A245 PolarHBondContact O-N 3.15Å; G242-A245 PolarHBondContact O-N 3.33Å; A245-F248 PolarHBondContact O-N 3Å; A245-W249 PolarHBondContact O-N 2.9Å; A245-M324 HydrophobicContact CB-CE 4.18Å; A245-Y327 HydrophobicContact CB-CD1 3.96Å; A245-Y327 HydrophobicContact CB-CE1 3.53Å; A245-F351 HydrophobicContact CB-CD2 4.34Å; A245-F351 HydrophobicContact CB-CE2 4.36Å; A245-M354 HydrophobicContact CB-SD 4.02Å
246	A	96.8	Very high	94.2	Very high	0 Å²	0	21.9 Å²	21.9	0%	0	11%	0.112	C	C	.	.	H	α-helix	trans	-66.4	-37.6	175.9	0	0	0	0	0	112.9	F130 G242 S243 F244 W249 L250 I317 M319 M324	F130-A246 HydrophobicContact CE1-CB 3.73Å; F130-A246 HydrophobicContact CZ-CB 3.7Å; G242-A246 VanDerWaalsContact O-CB 3.31Å; G242-A246 WeakPolarHBondContact O-CB 3.38Å; G242-A246 PolarHBondContact O-N 3.03Å; S243-A246 WeakPolarHBondContact O-CB 3.24Å; S243-A246 PolarHBondContact O-N 3Å; F244-A246 VanDerWaalsContact C-N 3.27Å; F244-A246 PolarHBondContact O-N 3.06Å; A246-W249 WeakPolarHBondContact O-CB 3.5Å; A246-W249 PolarHBondContact O-N 2.74Å; A246-L250 PolarHBondContact O-N 3.5Å; A246-I317 HydrophobicContact CB-CD1 3.68Å; A246-M319 HydrophobicContact CB-SD 4.18Å; A246-M324 HydrophobicContact CB-CE 4.43Å
247	I	96.5	Very high	94.5	Very high	6 Å²	6	24.2 Å²	24.2	3%	0.031	13%	0.127	C	C	.	.	H	α-helix	trans	-72.7	-37.6	174.3	-65.4	168.1	0	0	0	110.7	V134 F138 S243 F244 W249 L250 K251 L259 T260 N263	V134-I247 HydrophobicContact CG1-CD1 4.24Å; F138-I247 HydrophobicContact CE2-CD1 3.95Å; S243-I247 PolarHBondContact O-N 3.42Å; F244-I247 PolarHBondContact O-N 3.38Å; I247-W249 PolarHBondContact O-N 3.45Å; I247-L250 WeakPolarHBondContact O-CA 3.25Å; I247-L250 VanDerWaalsContact O-CB 3.29Å; I247-L250 WeakPolarHBondContact O-CB 3.21Å; I247-L250 PolarHBondContact O-N 3Å; I247-K251 PolarHBondContact O-N 3.22Å; I247-K251 VanDerWaalsContact O-N 3.11Å; I247-L259 HydrophobicContact CD1-CD1 4.3Å; I247-L259 HydrophobicContact CG2-CD2 4.42Å; I247-L259 HydrophobicContact CG2-CG 4Å; I247-T260 HydrophobicContact CG2-CG2 4Å; I247-N263 HydrophobicContact CB-CB 4.27Å; I247-N263 HydrophobicContact CD1-CB 4.46Å; I247-N263 WeakPolarHBondContact CD1-OD1 3.47Å; I247-N263 HydrophobicContact CG2-CB 3.55Å; I247-N263 VanDerWaalsContact CG2-CG 3.5Å
248	F	95.6	Very high	94.8	Very high	9 Å²	9	23.8 Å²	23.8	4%	0.039	12%	0.123	C	C	.	.	H	α-helix	trans	-62.2	-29.6	172.4	-77.8	-52.1	0	0	0	113.6	F244 A245 L250 K251 K252 N263 E264 F353 M354 I357	F244-F248 WeakPolarHBondContact O-CD2 3.4Å; F244-F248 PolarHBondContact O-N 3.3Å; A245-F248 PolarHBondContact O-N 3Å; F248-L250 VanDerWaalsContact C-N 3.31Å; F248-L250 PolarHBondContact O-N 3.34Å; F248-K251 HydrophobicContact CD1-CD 4.35Å; F248-K251 WeakPolarHBondContact O-CB 3.49Å; F248-K251 PolarHBondContact O-N 3.14Å; F248-K252 PolarHBondContact O-N 3.5Å; F248-N263 WeakPolarHBondContact CE2-ND2 3.11Å; F248-N263 WeakPolarHBondContact CZ-ND2 3.19Å; F248-E264 HydrophobicContact CE1-CG 3.52Å; F248-E264 HydrophobicContact CZ-CG 4.03Å; F248-F353 HydrophobicContact CB-CD2 3.97Å; F248-F353 HydrophobicContact CB-CE2 3.86Å; F248-M354 HydrophobicContact CB-SD 3.91Å; F248-M354 HydrophobicContact CD2-CE 3.73Å; F248-M354 HydrophobicContact CD2-SD 3.54Å; F248-M354 VanDerWaalsContact CD2-SD 3.54Å; F248-M354 HydrophobicContact CE2-CE 4.06Å; F248-M354 HydrophobicContact CE2-SD 4.42Å; F248-M354 HydrophobicContact CG-SD 4.02Å; F248-I357 HydrophobicContact CB-CD1 3.73Å; F248-I357 HydrophobicContact CD1-CD1 3.38Å; F248-I357 HydrophobicContact CD1-CG1 4.36Å; F248-I357 HydrophobicContact CD1-CG2 3.87Å; F248-I357 HydrophobicContact CE1-CD1 4.16Å; F248-I357 HydrophobicContact CE1-CG2 3.46Å; F248-I357 VanDerWaalsContact CE1-CG2 3.46Å; F248-I357 HydrophobicContact CG-CD1 3.71Å; F248-I357 HydrophobicContact CZ-CG2 3.91Å
249	W	96.2	Very high	94.9	Very high	64 Å²	64	23.9 Å²	23.9	24%	0.242	12%	0.123	C	C	.	.	H	α-helix	trans	-62.5	-37.8	169.6	171.4	-107.9	0	0	0	112.5	A245 A246 I247 K251 K252 R253 I317 M319 F353	A245-W249 PolarHBondContact O-N 2.9Å; A246-W249 WeakPolarHBondContact O-CB 3.5Å; A246-W249 PolarHBondContact O-N 2.74Å; I247-W249 PolarHBondContact O-N 3.45Å; W249-K251 VanDerWaalsContact C-N 3.32Å; W249-K252 HydrophobicContact CE3-CD 4.11Å; W249-K252 HydrophobicContact CZ3-CD 3.93Å; W249-K252 WeakPolarHBondContact O-CB 3.47Å; W249-K252 PolarHBondContact O-N 3.19Å; W249-R253 WeakPolarHBondContact O-CG 3.22Å; W249-R253 PolarHBondContact O-N 2.78Å; W249-I317 PolarHBondContact NE1-O 3.3Å; W249-M319 HydrophobicContact CB-CE 4.08Å; W249-M319 HydrophobicContact CB-CG 4.09Å; W249-M319 HydrophobicContact CB-SD 3.56Å; W249-M319 VanDerWaalsContact CB-SD 3.56Å; W249-M319 VanDerWaalsContact CD1-CG 3.45Å; W249-M319 HydrophobicContact CD2-CG 3.84Å; W249-M319 HydrophobicContact CD2-SD 4.46Å; W249-M319 HydrophobicContact CG-CE 4.42Å; W249-M319 HydrophobicContact CG-CG 3.52Å; W249-M319 HydrophobicContact CG-SD 3.69Å; W249-F353 HydrophobicContact CB-CZ 4.23Å; W249-F353 HydrophobicContact CE3-CD1 4.4Å; W249-F353 AromaticContact CE3-CE1 3.91Å; W249-F353 HydrophobicContact CE3-CE1 3.91Å; W249-F353 HydrophobicContact CE3-CZ 4.44Å
250	L	95.4	Very high	95.1	Very high	1 Å²	1	24 Å²	24	1%	0.005	13%	0.125	C	C	.	.	H	α-helix	trans	-64.9	-37.9	172.8	-57	176.6	0	0	0	111.6	I131 A246 I247 F248 K252 R253 G254 L255 L259 T260 I317	I131-L250 HydrophobicContact CD1-CD1 3.57Å; I131-L250 HydrophobicContact CG1-CD1 3.8Å; A246-L250 PolarHBondContact O-N 3.5Å; I247-L250 WeakPolarHBondContact O-CA 3.25Å; I247-L250 VanDerWaalsContact O-CB 3.29Å; I247-L250 WeakPolarHBondContact O-CB 3.21Å; I247-L250 PolarHBondContact O-N 3Å; F248-L250 VanDerWaalsContact C-N 3.31Å; F248-L250 PolarHBondContact O-N 3.34Å; L250-K252 PolarHBondContact O-N 3.33Å; L250-R253 CarbonylContact O-C 3.6Å; L250-R253 WeakPolarHBondContact O-CA 3.37Å; L250-R253 WeakPolarHBondContact O-CB 3.31Å; L250-R253 PolarHBondContact O-N 3.41Å; L250-G254 PolarHBondContact O-N 3.46Å; L250-G254 VanDerWaalsContact O-N 3.15Å; L250-L255 HydrophobicContact CB-CB 4.42Å; L250-L255 HydrophobicContact CD2-CD1 4.46Å; L250-L255 PolarHBondContact O-N 3.32Å; L250-L259 HydrophobicContact CD1-CD2 4.16Å; L250-T260 HydrophobicContact CB-CG2 4.26Å; L250-I317 HydrophobicContact CD2-CG2 4.47Å
251	K	94.8	Very high	95.6	Very high	56 Å²	56	28 Å²	28	24%	0.243	14%	0.142	C	C	.	.	H	α-helix	trans	-59.3	-45.8	172.9	-173	175.3	171.9	173.9	0	111.5	I247 F248 W249 R253 G254 T260 E264 I357	I247-K251 PolarHBondContact O-N 3.22Å; I247-K251 VanDerWaalsContact O-N 3.11Å; F248-K251 HydrophobicContact CD1-CD 4.35Å; F248-K251 WeakPolarHBondContact O-CB 3.49Å; F248-K251 PolarHBondContact O-N 3.14Å; W249-K251 VanDerWaalsContact C-N 3.32Å; K251-R253 PolarHBondContact O-N 2.83Å; K251-R253 VanDerWaalsContact O-N 3.15Å; K251-G254 PolarHBondContact O-N 2.98Å; K251-T260 HydrophobicContact CB-CG2 3.72Å; K251-E264 IonicContact NZ-OE1 3.37Å; K251-E264 PolarHBondContact NZ-OE1 3.26Å; K251-E264 IonicContact NZ-OE2 2.7Å; K251-E264 PolarHBondContact NZ-OE2 3.37Å; K251-I357 HydrophobicContact CD-CD1 4.47Å
252	K	93.6	Very high	95.8	Very high	103 Å²	103	27.7 Å²	27.7	45%	0.448	14%	0.14	S	C	.	.	H	α-helix	trans	-57.3	-29.3	175.6	-168.3	177.3	-166.4	171.6	0	112.2	F248 W249 L250 D352 F353	F248-K252 PolarHBondContact O-N 3.5Å; W249-K252 HydrophobicContact CE3-CD 4.11Å; W249-K252 HydrophobicContact CZ3-CD 3.93Å; W249-K252 WeakPolarHBondContact O-CB 3.47Å; W249-K252 PolarHBondContact O-N 3.19Å; L250-K252 PolarHBondContact O-N 3.33Å; K252-D352 IonicContact NZ-OD1 2.64Å; K252-D352 PolarHBondContact NZ-OD1 2.96Å; K252-D352 IonicContact NZ-OD2 3.8Å; K252-D352 PolarHBondContact NZ-OD2 3.03Å; K252-F353 HydrophobicContact CD-CB 3.95Å; K252-F353 HydrophobicContact CD-CD1 3.85Å; K252-F353 HydrophobicContact CD-CG 4.15Å
253	R	95	Very high	95.9	Very high	96 Å²	96	27.9 Å²	27.9	36%	0.362	14%	0.141	S	C	.	.	T	Hydrogen-bonded Turn	trans	-87.7	-3.3	176.7	-65.9	174.5	57.6	-163.2	-5.8	114.2	E127 W249 L250 K251 L255 I317	E127-R253 IonicContact OE1-CZ 3.27Å; E127-R253 IonicContact OE1-NH1 3.19Å; E127-R253 PolarHBondContact OE1-NH1 3.28Å; E127-R253 IonicContact OE1-NH2 2.73Å; E127-R253 PolarHBondContact OE1-NH2 3.4Å; W249-R253 WeakPolarHBondContact O-CG 3.22Å; W249-R253 PolarHBondContact O-N 2.78Å; L250-R253 CarbonylContact O-C 3.6Å; L250-R253 WeakPolarHBondContact O-CA 3.37Å; L250-R253 WeakPolarHBondContact O-CB 3.31Å; L250-R253 PolarHBondContact O-N 3.41Å; K251-R253 PolarHBondContact O-N 2.83Å; K251-R253 VanDerWaalsContact O-N 3.15Å; R253-L255 HydrophobicContact CB-CD1 3.94Å; R253-L255 HydrophobicContact CB-CG 4.06Å; R253-I317 PolarHBondContact NH1-O 3.39Å
254	G	94.8	Very high	95.8	Very high	55 Å²	55	29.8 Å²	29.8	57%	0.567	15%	0.15	S	C	*	.	T	Hydrogen-bonded Turn	trans	71.7	30.7	-178.4	0	0	0	0	0	114	L250 K251	L250-G254 PolarHBondContact O-N 3.46Å; L250-G254 VanDerWaalsContact O-N 3.15Å; K251-G254 PolarHBondContact O-N 2.98Å
255	L	96.3	Very high	95.8	Very high	29 Å²	29	29.6 Å²	29.6	15%	0.152	15%	0.15	C	C	.	.			trans	-109.1	151	-176.5	-59.9	172.7	0	0	0	111.6	L123 L250 R253 T260	L123-L255 HydrophobicContact CD2-CD1 3.93Å; L123-L255 HydrophobicContact CD2-CD2 4.46Å; L250-L255 HydrophobicContact CB-CB 4.42Å; L250-L255 HydrophobicContact CD2-CD1 4.46Å; L250-L255 PolarHBondContact O-N 3.32Å; R253-L255 HydrophobicContact CB-CD1 3.94Å; R253-L255 HydrophobicContact CB-CG 4.06Å; L255-T260 WeakPolarHBondContact O-CG2 3.38Å
256	M	97.3	Very high	95.8	Very high	0 Å²	0	29.6 Å²	29.6	0%	0	15%	0.15	C	C	.	.			trans	50.8	65.6	171.1	-52.3	-61.3	-63.6	0	0	113.2	D116 H119 W120 L123 Y187 G258 L259 T260	D116-M256 HydrophobicContact CB-CE 4Å; H119-M256 HydrophobicContact CB-SD 3.53Å; H119-M256 VanDerWaalsContact CB-SD 3.53Å; H119-M256 PolarHBondContact ND1-N 3.34Å; W120-M256 HydrophobicContact CB-CE 4.11Å; W120-M256 HydrophobicContact CB-SD 4.26Å; W120-M256 HydrophobicContact CE3-CE 4.01Å; L123-M256 HydrophobicContact CD1-CG 4.24Å; L123-M256 HydrophobicContact CD1-SD 3.94Å; Y187-M256 HydrophobicContact CD1-CE 4.18Å; Y187-M256 HydrophobicContact CD2-CE 4.36Å; Y187-M256 HydrophobicContact CE1-CE 3.63Å; Y187-M256 HydrophobicContact CE2-CE 3.81Å; M256-G258 VanDerWaalsContact C-N 3.34Å; M256-G258 PolarHBondContact O-N 3.39Å; M256-L259 HydrophobicContact CB-CB 3.71Å; M256-L259 HydrophobicContact CB-CD2 4.01Å; M256-L259 HydrophobicContact CB-CG 4.45Å; M256-L259 HydrophobicContact CG-CD2 4.32Å; M256-L259 PolarHBondContact O-N 2.92Å; M256-T260 WeakPolarHBondContact O-CG2 3.24Å; M256-T260 PolarHBondContact O-N 3Å; M256-T260 PolarHBondContact O-OG1 3.23Å
257	P	96.1	Very high	95.6	Very high	52 Å²	52	30.8 Å²	30.8	34%	0.338	16%	0.158	S	C	.	.	H	α-helix	trans	-60.3	-38.8	-172.1	23.4	-32.5	0	0	0	113.5	K115 D116 T260 F261	K115-P257 HydrophobicContact CB-CG 4.13Å; D116-P257 WeakPolarHBondContact OD2-CD 3.27Å; D116-P257 WeakPolarHBondContact OD2-CG 3Å; P257-T260 WeakPolarHBondContact CA-OG1 3.29Å; P257-T260 PolarHBondContact O-OG1 2.68Å; P257-T260 VanDerWaalsContact O-OG1 3.13Å; P257-F261 WeakPolarHBondContact O-CB 3.35Å; P257-F261 PolarHBondContact O-N 3.1Å
258	G	96.3	Very high	95.4	Very high	2 Å²	2	33.5 Å²	33.5	2%	0.021	17%	0.168	C	C	.	.	H	α-helix	trans	-68.7	-44.2	175.9	0	0	0	0	0	113.2	V111 D116 M256 T260 F261 S262	V111-G258 WeakPolarHBondContact CG1-O 3.37Å; D116-G258 VanDerWaalsContact CG-N 3.32Å; D116-G258 WeakPolarHBondContact OD1-CA 3.44Å; D116-G258 PolarHBondContact OD1-N 3.05Å; D116-G258 VanDerWaalsContact OD1-N 3.16Å; D116-G258 WeakPolarHBondContact OD2-CA 3.16Å; D116-G258 PolarHBondContact OD2-N 3.45Å; M256-G258 VanDerWaalsContact C-N 3.34Å; M256-G258 PolarHBondContact O-N 3.39Å; G258-T260 PolarHBondContact O-N 3.23Å; G258-F261 PolarHBondContact O-N 3.06Å; G258-S262 WeakPolarHBondContact O-CB 3.45Å; G258-S262 PolarHBondContact O-N 3.37Å; G258-S262 PolarHBondContact O-OG 3.42Å
259	L	97.6	Very high	95.4	Very high	2 Å²	2	33.4 Å²	33.4	1%	0.01	17%	0.168	C	C	.	.	H	α-helix	trans	-58	-47.3	172.5	177.6	60.7	0	0	0	111.7	D116 I131 L135 L183 Y187 I247 L250 M256 S262 N263	D116-L259 PolarHBondContact OD1-N 3.41Å; I131-L259 HydrophobicContact CG2-CD2 3.78Å; L135-L259 HydrophobicContact CD2-CD1 3.87Å; L183-L259 HydrophobicContact CD1-CD1 3.91Å; L183-L259 HydrophobicContact CD2-CB 4.44Å; L183-L259 HydrophobicContact CD2-CD1 4.26Å; Y187-L259 WeakPolarHBondContact OH-CB 3.45Å; I247-L259 HydrophobicContact CD1-CD1 4.3Å; I247-L259 HydrophobicContact CG2-CD2 4.42Å; I247-L259 HydrophobicContact CG2-CG 4Å; L250-L259 HydrophobicContact CD1-CD2 4.16Å; M256-L259 HydrophobicContact CB-CB 3.71Å; M256-L259 HydrophobicContact CB-CD2 4.01Å; M256-L259 HydrophobicContact CB-CG 4.45Å; M256-L259 HydrophobicContact CG-CD2 4.32Å; M256-L259 PolarHBondContact O-N 2.92Å; L259-S262 PolarHBondContact O-OG 3.31Å; L259-N263 VanDerWaalsContact O-CB 3.24Å; L259-N263 WeakPolarHBondContact O-CB 3.41Å; L259-N263 PolarHBondContact O-N 3.13Å
260	T	96.4	Very high	95.3	Very high	8 Å²	8	30.5 Å²	30.5	5%	0.049	16%	0.157	C	C	.	.	H	α-helix	trans	-71.9	-35.3	-175.8	55.2	0	0	0	0	112.1	I247 L250 K251 L255 M256 P257 G258 N263 E264	I247-T260 HydrophobicContact CG2-CG2 4Å; L250-T260 HydrophobicContact CB-CG2 4.26Å; K251-T260 HydrophobicContact CB-CG2 3.72Å; L255-T260 WeakPolarHBondContact O-CG2 3.38Å; M256-T260 WeakPolarHBondContact O-CG2 3.24Å; M256-T260 PolarHBondContact O-N 3Å; M256-T260 PolarHBondContact O-OG1 3.23Å; P257-T260 WeakPolarHBondContact CA-OG1 3.29Å; P257-T260 PolarHBondContact O-OG1 2.68Å; P257-T260 VanDerWaalsContact O-OG1 3.13Å; G258-T260 PolarHBondContact O-N 3.23Å; T260-N263 PolarHBondContact O-N 3.38Å; T260-E264 WeakPolarHBondContact O-CG 3.45Å; T260-E264 PolarHBondContact O-N 3.47Å; T260-E264 VanDerWaalsContact O-N 3.08Å
261	F	95.9	Very high	95.1	Very high	84 Å²	84	31.8 Å²	31.8	37%	0.368	17%	0.171	S	C	.	.	H	α-helix	trans	-68.3	-46	174.6	179.9	-116.6	0	0	0	112.5	V111 P257 G258 N263 E264 L265	V111-F261 HydrophobicContact CG1-CD1 4.3Å; V111-F261 HydrophobicContact CG2-CD1 4.15Å; V111-F261 HydrophobicContact CG2-CE1 4.29Å; P257-F261 WeakPolarHBondContact O-CB 3.35Å; P257-F261 PolarHBondContact O-N 3.1Å; G258-F261 PolarHBondContact O-N 3.06Å; F261-N263 VanDerWaalsContact C-N 3.28Å; F261-N263 PolarHBondContact O-N 3.35Å; F261-E264 WeakPolarHBondContact O-CB 3.34Å; F261-E264 PolarHBondContact O-N 2.9Å; F261-E264 VanDerWaalsContact O-N 3.11Å; F261-L265 HydrophobicContact CD1-CD1 4.45Å; F261-L265 HydrophobicContact CE1-CD1 3.93Å; F261-L265 HydrophobicContact CZ-CD1 4.06Å; F261-L265 HydrophobicContact CZ-CD2 4.47Å; F261-L265 HydrophobicContact CZ-CG 4.45Å; F261-L265 PolarHBondContact O-N 3.49Å
262	S	96.3	Very high	95.1	Very high	1 Å²	1	29.6 Å²	29.6	1%	0.007	16%	0.161	C	C	.	.	H	α-helix	trans	-60.5	-39.5	173.6	49.3	0	0	0	0	111.8	G258 L259 E264 L265 I266	G258-S262 WeakPolarHBondContact O-CB 3.45Å; G258-S262 PolarHBondContact O-N 3.37Å; G258-S262 PolarHBondContact O-OG 3.42Å; L259-S262 PolarHBondContact O-OG 3.31Å; S262-E264 VanDerWaalsContact C-N 3.3Å; S262-E264 PolarHBondContact O-N 2.94Å; S262-L265 PolarHBondContact O-N 2.95Å; S262-L265 VanDerWaalsContact O-N 3.13Å; S262-I266 WeakPolarHBondContact O-CG1 3.39Å; S262-I266 PolarHBondContact O-N 3.39Å
263	N	96.4	Very high	95.2	Very high	3 Å²	3	24.9 Å²	24.9	2%	0.016	14%	0.141	C	C	.	.	H	α-helix	trans	-61	-33.9	173.8	-178.3	88.2	0	0	0	113.2	F244 I247 F248 L259 T260 F261 S267	F244-N263 WeakPolarHBondContact CD1-OD1 3.48Å; I247-N263 HydrophobicContact CB-CB 4.27Å; I247-N263 HydrophobicContact CD1-CB 4.46Å; I247-N263 WeakPolarHBondContact CD1-OD1 3.47Å; I247-N263 HydrophobicContact CG2-CB 3.55Å; I247-N263 VanDerWaalsContact CG2-CG 3.5Å; F248-N263 WeakPolarHBondContact CE2-ND2 3.11Å; F248-N263 WeakPolarHBondContact CZ-ND2 3.19Å; L259-N263 VanDerWaalsContact O-CB 3.24Å; L259-N263 WeakPolarHBondContact O-CB 3.41Å; L259-N263 PolarHBondContact O-N 3.13Å; T260-N263 PolarHBondContact O-N 3.38Å; F261-N263 VanDerWaalsContact C-N 3.28Å; F261-N263 PolarHBondContact O-N 3.35Å; N263-S267 WeakPolarHBondContact O-CB 3.35Å; N263-S267 PolarHBondContact O-N 2.93Å; N263-S267 PolarHBondContact O-OG 3.17Å
264	E	93.8	Very high	95.2	Very high	41 Å²	41	20.6 Å²	20.6	19%	0.192	13%	0.126	C	C	.	.	H	α-helix	trans	-63.3	-42.3	172.6	-74.6	172.9	-107.4	0	0	112.5	F248 K251 T260 F261 S262 S267 R268	F248-E264 HydrophobicContact CE1-CG 3.52Å; F248-E264 HydrophobicContact CZ-CG 4.03Å; K251-E264 IonicContact NZ-OE1 3.37Å; K251-E264 PolarHBondContact NZ-OE1 3.26Å; K251-E264 IonicContact NZ-OE2 2.7Å; K251-E264 PolarHBondContact NZ-OE2 3.37Å; T260-E264 WeakPolarHBondContact O-CG 3.45Å; T260-E264 PolarHBondContact O-N 3.47Å; T260-E264 VanDerWaalsContact O-N 3.08Å; F261-E264 WeakPolarHBondContact O-CB 3.34Å; F261-E264 PolarHBondContact O-N 2.9Å; F261-E264 VanDerWaalsContact O-N 3.11Å; S262-E264 VanDerWaalsContact C-N 3.3Å; S262-E264 PolarHBondContact O-N 2.94Å; E264-S267 PolarHBondContact O-OG 3.16Å; E264-R268 WeakPolarHBondContact O-CB 3.4Å; E264-R268 PolarHBondContact O-N 2.91Å
265	L	95.1	Very high	95.2	Very high	10 Å²	10	20.9 Å²	20.9	5%	0.052	11%	0.114	C	C	.	.	H	α-helix	trans	-68.3	-48.5	179.6	-60.3	175.9	0	0	0	110.8	W106 V111 F261 S262 R268 D269	W106-L265 HydrophobicContact CD2-CB 4.03Å; W106-L265 HydrophobicContact CD2-CD1 3.69Å; W106-L265 HydrophobicContact CD2-CG 4.41Å; W106-L265 HydrophobicContact CE3-CD1 3.61Å; W106-L265 HydrophobicContact CG-CB 4.46Å; W106-L265 HydrophobicContact CG-CD1 4.1Å; W106-L265 HydrophobicContact CH2-CB 4.43Å; W106-L265 HydrophobicContact CZ2-CB 3.89Å; W106-L265 HydrophobicContact CZ3-CD1 4.1Å; V111-L265 HydrophobicContact CG2-CD1 4.25Å; F261-L265 HydrophobicContact CD1-CD1 4.45Å; F261-L265 HydrophobicContact CE1-CD1 3.93Å; F261-L265 HydrophobicContact CZ-CD1 4.06Å; F261-L265 HydrophobicContact CZ-CD2 4.47Å; F261-L265 HydrophobicContact CZ-CG 4.45Å; F261-L265 PolarHBondContact O-N 3.49Å; S262-L265 PolarHBondContact O-N 2.95Å; S262-L265 VanDerWaalsContact O-N 3.13Å; L265-R268 WeakPolarHBondContact O-CB 3.21Å; L265-R268 PolarHBondContact O-N 3.4Å; L265-D269 VanDerWaalsContact O-CG 3.27Å; L265-D269 PolarHBondContact O-N 2.91Å; L265-D269 VanDerWaalsContact O-N 3.17Å
266	I	95.5	Very high	95.3	Very high	0 Å²	0	19.6 Å²	19.6	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-66.9	-50	-177.9	-61.8	165.5	0	0	0	110.7	W106 M179 Y180 F244 S262 R268 D269 E270	W106-I266 HydrophobicContact CH2-CD1 4.36Å; W106-I266 HydrophobicContact CH2-CG1 3.94Å; W106-I266 HydrophobicContact CZ2-CG1 3.67Å; M179-I266 HydrophobicContact CG-CD1 4.32Å; Y180-I266 HydrophobicContact CE1-CD1 3.94Å; Y180-I266 HydrophobicContact CE2-CD1 3.99Å; Y180-I266 WeakPolarHBondContact OH-CG2 3.38Å; F244-I266 HydrophobicContact CE1-CG2 4.18Å; F244-I266 HydrophobicContact CZ-CG2 4.06Å; S262-I266 WeakPolarHBondContact O-CG1 3.39Å; S262-I266 PolarHBondContact O-N 3.39Å; I266-R268 PolarHBondContact O-N 3.21Å; I266-R268 VanDerWaalsContact O-N 3.13Å; I266-D269 WeakPolarHBondContact O-CA 3.46Å; I266-D269 WeakPolarHBondContact O-CB 3.41Å; I266-D269 PolarHBondContact O-N 2.93Å; I266-E270 HydrophobicContact CG2-CG 4.12Å; I266-E270 WeakPolarHBondContact O-CG 3.45Å; I266-E270 PolarHBondContact O-N 2.91Å
267	S	93.1	Very high	95.3	Very high	25 Å²	25	19.7 Å²	19.7	18%	0.175	11%	0.108	C	C	.	.	H	α-helix	trans	-61.8	-26.9	-179.5	62.9	0	0	0	0	113.8	N263 E264 G271	N263-S267 WeakPolarHBondContact O-CB 3.35Å; N263-S267 PolarHBondContact O-N 2.93Å; N263-S267 PolarHBondContact O-OG 3.17Å; E264-S267 PolarHBondContact O-OG 3.16Å; S267-G271 PolarHBondContact O-N 3.29Å; S267-G271 VanDerWaalsContact O-N 3.1Å
268	R	92.8	Very high	95.4	Very high	63 Å²	63	17.3 Å²	17.3	24%	0.238	9%	0.093	C	C	.	.	H	α-helix	trans	-69	-44.7	170.8	175.9	-154.5	66.9	-163.1	-2.5	111.3	S104 W106 E264 L265 I266 G271 L272	S104-R268 PolarHBondContact O-NH2 3.46Å; W106-R268 VanDerWaalsContact CD1-NH2 3.3Å; E264-R268 WeakPolarHBondContact O-CB 3.4Å; E264-R268 PolarHBondContact O-N 2.91Å; L265-R268 WeakPolarHBondContact O-CB 3.21Å; L265-R268 PolarHBondContact O-N 3.4Å; I266-R268 PolarHBondContact O-N 3.21Å; I266-R268 VanDerWaalsContact O-N 3.13Å; R268-G271 PolarHBondContact O-N 2.84Å; R268-L272 PolarHBondContact O-N 3.21Å
269	D	95.3	Very high	95.4	Very high	6 Å²	6	18.3 Å²	18.3	3%	0.032	10%	0.097	C	C	.	.	H	α-helix	trans	-63.6	-48.7	179.4	-65	-11.3	0	0	0	110.2	W106 H176 L265 I266 G271 L272 H273	W106-D269 PolarHBondContact NE1-OD2 3.2Å; H176-D269 IonicContact CE1-OD2 3.53Å; H176-D269 IonicContact NE2-OD2 3.7Å; H176-D269 PolarHBondContact NE2-OD2 3.1Å; L265-D269 VanDerWaalsContact O-CG 3.27Å; L265-D269 PolarHBondContact O-N 2.91Å; L265-D269 VanDerWaalsContact O-N 3.17Å; I266-D269 WeakPolarHBondContact O-CA 3.46Å; I266-D269 WeakPolarHBondContact O-CB 3.41Å; I266-D269 PolarHBondContact O-N 2.93Å; D269-G271 VanDerWaalsContact C-N 3.27Å; D269-G271 PolarHBondContact O-N 3.36Å; D269-L272 CarbonylContact O-C 3.51Å; D269-L272 WeakPolarHBondContact O-CA 3.47Å; D269-L272 WeakPolarHBondContact O-CB 3.4Å; D269-L272 PolarHBondContact O-N 3.4Å; D269-H273 PolarHBondContact O-CD2 2.86Å; D269-H273 VanDerWaalsContact O-CD2 3.29Å; D269-H273 VanDerWaalsContact O-CG 3.23Å; D269-H273 PolarHBondContact O-N 2.88Å
270	E	93.8	Very high	95.4	Very high	3 Å²	3	18.2 Å²	18.2	1%	0.014	10%	0.097	C	C	.	.	H	α-helix	trans	-58.5	-38.1	175.1	-62.8	-45.8	101.1	0	0	112.6	H176 F244 I266 L272 H273 C274	H176-E270 IonicContact CE1-OE1 3.72Å; H176-E270 PolarHBondContact CE1-OE1 3.01Å; H176-E270 VanDerWaalsContact CE1-OE1 3.26Å; H176-E270 IonicContact ND1-OE1 2.57Å; H176-E270 PolarHBondContact ND1-OE1 2.85Å; F244-E270 HydrophobicContact CE2-CB 3.95Å; F244-E270 HydrophobicContact CE2-CG 3.78Å; F244-E270 HydrophobicContact CZ-CB 4.3Å; F244-E270 HydrophobicContact CZ-CG 3.63Å; I266-E270 HydrophobicContact CG2-CG 4.12Å; I266-E270 WeakPolarHBondContact O-CG 3.45Å; I266-E270 PolarHBondContact O-N 2.91Å; E270-L272 VanDerWaalsContact C-N 3.32Å; E270-L272 PolarHBondContact O-N 3.13Å; E270-H273 PolarHBondContact O-N 3.28Å; E270-H273 IonicContact OE1-CE1 3.85Å; E270-H273 IonicContact OE1-ND1 3.4Å; E270-H273 PolarHBondContact OE1-ND1 3.44Å; E270-C274 VanDerWaalsContact O-CB 3.28Å; E270-C274 WeakPolarHBondContact O-CB 3.41Å; E270-C274 PolarHBondContact O-N 3.26Å
271	G	91.8	Very high	95.5	Very high	29 Å²	29	17.8 Å²	17.8	30%	0.299	10%	0.095	S	C	.	.	H	α-helix	trans	-60.1	-42.7	172.4	0	0	0	0	0	112.1	S267 R268 D269 D275	S267-G271 PolarHBondContact O-N 3.29Å; S267-G271 VanDerWaalsContact O-N 3.1Å; R268-G271 PolarHBondContact O-N 2.84Å; D269-G271 VanDerWaalsContact C-N 3.27Å; D269-G271 PolarHBondContact O-N 3.36Å; G271-D275 VanDerWaalsContact O-CG 3.31Å; G271-D275 PolarHBondContact O-N 3.32Å
272	L	93.8	Very high	95.5	Very high	9 Å²	9	19.4 Å²	19.4	5%	0.047	10%	0.101	C	C	.	.	H	α-helix	trans	-69.9	-37	177.3	-178.2	62.3	0	0	0	112.5	M97 K100 A101 F165 R268 D269 E270 D275 F276	M97-L272 HydrophobicContact SD-CD1 3.86Å; K100-L272 HydrophobicContact CD-CD1 3.69Å; K100-L272 HydrophobicContact CG-CD1 4.18Å; K100-L272 HydrophobicContact CG-CD2 4.29Å; A101-L272 VanDerWaalsContact CA-CD2 3.49Å; A101-L272 HydrophobicContact CB-CD2 3.66Å; F165-L272 HydrophobicContact CE2-CD2 4.5Å; F165-L272 HydrophobicContact CE2-CG 4.26Å; F165-L272 HydrophobicContact CZ-CG 4.18Å; R268-L272 PolarHBondContact O-N 3.21Å; D269-L272 CarbonylContact O-C 3.51Å; D269-L272 WeakPolarHBondContact O-CA 3.47Å; D269-L272 WeakPolarHBondContact O-CB 3.4Å; D269-L272 PolarHBondContact O-N 3.4Å; E270-L272 VanDerWaalsContact C-N 3.32Å; E270-L272 PolarHBondContact O-N 3.13Å; L272-D275 WeakPolarHBondContact O-CB 3.49Å; L272-D275 PolarHBondContact O-N 3.14Å; L272-F276 WeakPolarHBondContact O-CB 3.45Å; L272-F276 PolarHBondContact O-N 2.94Å
273	H	95.9	Very high	95.5	Very high	4 Å²	4	21.8 Å²	21.8	2%	0.019	11%	0.112	C	C	.	.	H	α-helix	trans	-65.6	-41.9	175.2	-60	165	0	0	0	111.4	Q169 E173 E236 D269 E270 F276 A277	Q169-H273 VanDerWaalsContact NE2-CG 3.31Å; Q169-H273 PolarHBondContact NE2-ND1 2.94Å; E173-H273 IonicContact OE1-CE1 2.61Å; E173-H273 PolarHBondContact OE1-CE1 3.14Å; E173-H273 IonicContact OE1-ND1 2.74Å; E173-H273 PolarHBondContact OE1-ND1 3.46Å; E236-H273 HydrophobicContact CG-CB 4.42Å; E236-H273 WeakPolarHBondContact OE2-CB 3.34Å; E236-H273 IonicContact OE2-CG 3.91Å; E236-H273 IonicContact OE2-ND1 3.71Å; E236-H273 PolarHBondContact OE2-ND1 3.23Å; E236-H273 VanDerWaalsContact OE2-ND1 3.11Å; D269-H273 PolarHBondContact O-CD2 2.86Å; D269-H273 VanDerWaalsContact O-CD2 3.29Å; D269-H273 VanDerWaalsContact O-CG 3.23Å; D269-H273 PolarHBondContact O-N 2.88Å; E270-H273 PolarHBondContact O-N 3.28Å; E270-H273 IonicContact OE1-CE1 3.85Å; E270-H273 IonicContact OE1-ND1 3.4Å; E270-H273 PolarHBondContact OE1-ND1 3.44Å; H273-F276 WeakPolarHBondContact O-CB 3.46Å; H273-F276 PolarHBondContact O-N 2.94Å; H273-A277 PolarHBondContact O-N 3.29Å
274	C	95.7	Very high	95.5	Very high	6 Å²	6	21.9 Å²	21.9	4%	0.041	11%	0.113	C	C	.	.	H	α-helix	trans	-63	-45.5	173.7	-172.9	0	0	0	0	112	E236 E270 F276 A277 C278	E236-C274 HydrophobicContact CB-CB 4.22Å; E270-C274 VanDerWaalsContact O-CB 3.28Å; E270-C274 WeakPolarHBondContact O-CB 3.41Å; E270-C274 PolarHBondContact O-N 3.26Å; C274-F276 PolarHBondContact O-N 2.94Å; C274-A277 PolarHBondContact O-N 3.22Å; C274-C278 PolarHBondContact O-N 2.95Å; C274-C278 PolarHBondContact O-SG 3.19Å; C274-C278 VanDerWaalsContact O-SG 3.34Å
275	D	95.1	Very high	95.5	Very high	62 Å²	62	24.4 Å²	24.4	33%	0.332	13%	0.131	S	C	.	.	H	α-helix	trans	-55.4	-42.6	172.6	-78.6	-15.1	0	0	0	110.9	G271 L272 C278 L279	G271-D275 VanDerWaalsContact O-CG 3.31Å; G271-D275 PolarHBondContact O-N 3.32Å; L272-D275 WeakPolarHBondContact O-CB 3.49Å; L272-D275 PolarHBondContact O-N 3.14Å; D275-C278 WeakPolarHBondContact O-CB 3.3Å; D275-C278 PolarHBondContact O-N 3.5Å; D275-L279 PolarHBondContact O-N 2.99Å
276	F	97.5	Very high	95.4	Very high	1 Å²	1	27.7 Å²	27.7	0%	0.004	15%	0.148	C	C	.	.	H	α-helix	trans	-66.9	-43.4	179.2	-173.1	-103.1	0	0	0	112.1	I94 M97 A162 F165 Y166 L272 H273 C274 C278 L279 M280	I94-F276 HydrophobicContact CG2-CE2 3.81Å; I94-F276 HydrophobicContact CG2-CZ 4.09Å; M97-F276 HydrophobicContact CB-CD2 3.85Å; M97-F276 HydrophobicContact CB-CE2 4.33Å; M97-F276 HydrophobicContact CG-CD2 4.24Å; A162-F276 HydrophobicContact CB-CZ 4.04Å; F165-F276 HydrophobicContact CB-CD2 4.28Å; F165-F276 HydrophobicContact CB-CE1 4.02Å; F165-F276 HydrophobicContact CB-CE2 3.65Å; F165-F276 HydrophobicContact CB-CZ 3.51Å; F165-F276 HydrophobicContact CD1-CB 4.17Å; F165-F276 AromaticContact CD1-CD1 3.26Å; F165-F276 HydrophobicContact CD1-CD1 3.26Å; F165-F276 AromaticContact CD1-CD2 3.77Å; F165-F276 HydrophobicContact CD1-CD2 3.77Å; F165-F276 AromaticContact CD1-CE1 3.43Å; F165-F276 HydrophobicContact CD1-CE1 3.43Å; F165-F276 VanDerWaalsContact CD1-CE1 3.43Å; F165-F276 AromaticContact CD1-CE2 3.91Å; F165-F276 HydrophobicContact CD1-CE2 3.91Å; F165-F276 AromaticContact CD1-CG 3.44Å; F165-F276 HydrophobicContact CD1-CG 3.44Å; F165-F276 VanDerWaalsContact CD1-CG 3.44Å; F165-F276 AromaticContact CD1-CZ 3.76Å; F165-F276 HydrophobicContact CD1-CZ 3.76Å; F165-F276 AromaticContact CD2-CD2 3.52Å; F165-F276 HydrophobicContact CD2-CD2 3.52Å; F165-F276 AromaticContact CD2-CE2 3.71Å; F165-F276 HydrophobicContact CD2-CE2 3.71Å; F165-F276 AromaticContact CD2-CG 3.97Å; F165-F276 HydrophobicContact CD2-CG 3.97Å; F165-F276 HydrophobicContact CD2-CZ 4.32Å; F165-F276 HydrophobicContact CE1-CB 3.52Å; F165-F276 AromaticContact CE1-CD1 3.42Å; F165-F276 HydrophobicContact CE1-CD1 3.42Å; F165-F276 VanDerWaalsContact CE1-CD1 3.42Å; F165-F276 AromaticContact CE1-CD2 3.94Å; F165-F276 HydrophobicContact CE1-CD2 3.94Å; F165-F276 HydrophobicContact CE1-CE1 4.09Å; F165-F276 AromaticContact CE1-CG 3.33Å; F165-F276 HydrophobicContact CE1-CG 3.33Å; F165-F276 HydrophobicContact CE2-CB 3.98Å; F165-F276 AromaticContact CE2-CD2 3.71Å; F165-F276 HydrophobicContact CE2-CD2 3.71Å; F165-F276 HydrophobicContact CE2-CE2 4.37Å; F165-F276 AromaticContact CE2-CG 3.87Å; F165-F276 HydrophobicContact CE2-CG 3.87Å; F165-F276 AromaticContact CG-CD1 3.89Å; F165-F276 HydrophobicContact CG-CD1 3.89Å; F165-F276 AromaticContact CG-CD2 3.57Å; F165-F276 HydrophobicContact CG-CD2 3.57Å; F165-F276 AromaticContact CG-CE1 3.8Å; F165-F276 HydrophobicContact CG-CE1 3.8Å; F165-F276 AromaticContact CG-CE2 3.46Å; F165-F276 HydrophobicContact CG-CE2 3.46Å; F165-F276 VanDerWaalsContact CG-CE2 3.46Å; F165-F276 AromaticContact CG-CG 3.78Å; F165-F276 HydrophobicContact CG-CG 3.78Å; F165-F276 AromaticContact CG-CZ 3.59Å; F165-F276 HydrophobicContact CG-CZ 3.59Å; F165-F276 HydrophobicContact CZ-CB 3.41Å; F165-F276 VanDerWaalsContact CZ-CB 3.41Å; F165-F276 HydrophobicContact CZ-CD1 4.15Å; F165-F276 AromaticContact CZ-CD2 3.92Å; F165-F276 HydrophobicContact CZ-CD2 3.92Å; F165-F276 AromaticContact CZ-CG 3.56Å; F165-F276 HydrophobicContact CZ-CG 3.56Å; Y166-F276 HydrophobicContact CD1-CE1 4.12Å; Y166-F276 AromaticContact CE1-CD1 3.95Å; Y166-F276 HydrophobicContact CE1-CD1 3.95Å; Y166-F276 AromaticContact CE1-CE1 3.65Å; Y166-F276 HydrophobicContact CE1-CE1 3.65Å; Y166-F276 HydrophobicContact CE2-CE1 4.12Å; Y166-F276 AromaticContact CZ-CE1 3.66Å; L272-F276 WeakPolarHBondContact O-CB 3.45Å; L272-F276 PolarHBondContact O-N 2.94Å; H273-F276 WeakPolarHBondContact O-CB 3.46Å; H273-F276 PolarHBondContact O-N 2.94Å; C274-F276 PolarHBondContact O-N 2.94Å; F276-C278 VanDerWaalsContact C-N 3.26Å; F276-C278 PolarHBondContact O-N 2.99Å; F276-L279 WeakPolarHBondContact O-CA 3.08Å; F276-L279 WeakPolarHBondContact O-CB 3.38Å; F276-L279 PolarHBondContact O-N 3.49Å; F276-M280 HydrophobicContact CD1-CG 3.95Å; F276-M280 HydrophobicContact CE1-CG 3.58Å; F276-M280 HydrophobicContact CE1-SD 3.87Å; F276-M280 HydrophobicContact CE2-SD 4.25Å; F276-M280 HydrophobicContact CZ-CG 3.91Å; F276-M280 HydrophobicContact CZ-SD 3.6Å; F276-M280 VanDerWaalsContact CZ-SD 3.6Å; F276-M280 WeakPolarHBondContact O-CG 3.44Å; F276-M280 PolarHBondContact O-N 3.32Å
277	A	97.1	Very high	95.4	Very high	2 Å²	2	32.1 Å²	32.1	2%	0.017	17%	0.168	C	C	.	.	H	α-helix	trans	-57.9	-41.5	173.4	0	0	0	0	0	111.3	V229 F232 A233 H273 C274 L279 M280 F281	V229-A277 HydrophobicContact CG1-CB 4.36Å; V229-A277 WeakPolarHBondContact CG1-O 3.5Å; F232-A277 HydrophobicContact CD1-CB 4.2Å; A233-A277 HydrophobicContact CB-CB 3.77Å; H273-A277 PolarHBondContact O-N 3.29Å; C274-A277 PolarHBondContact O-N 3.22Å; A277-L279 PolarHBondContact O-N 3.37Å; A277-M280 PolarHBondContact O-N 2.84Å; A277-F281 WeakPolarHBondContact O-CB 3.3Å; A277-F281 PolarHBondContact O-N 2.91Å
278	C	97.4	Very high	95.5	Very high	2 Å²	2	31.5 Å²	31.5	1%	0.014	16%	0.163	C	C	.	.	H	α-helix	trans	-64.4	-37.9	173.7	-65.5	0	0	0	0	112.6	C274 D275 F276 F281 K282 L335 E338 L339	C274-C278 PolarHBondContact O-N 2.95Å; C274-C278 PolarHBondContact O-SG 3.19Å; C274-C278 VanDerWaalsContact O-SG 3.34Å; D275-C278 WeakPolarHBondContact O-CB 3.3Å; D275-C278 PolarHBondContact O-N 3.5Å; F276-C278 VanDerWaalsContact C-N 3.26Å; F276-C278 PolarHBondContact O-N 2.99Å; C278-F281 WeakPolarHBondContact O-CB 3.48Å; C278-F281 PolarHBondContact O-N 3.46Å; C278-K282 WeakPolarHBondContact O-CG 3.14Å; C278-K282 PolarHBondContact O-N 3.4Å; C278-L335 WeakPolarHBondContact SG-CD1 2.88Å; C278-E338 HydrophobicContact CB-CB 4.38Å; C278-L339 HydrophobicContact CB-CD2 4.35Å
279	L	97.8	Very high	95.7	Very high	23 Å²	23	32.5 Å²	32.5	12%	0.12	18%	0.178	C	C	.	.	H	α-helix	trans	-64	-45.6	173.8	-179.5	61.6	0	0	0	111.6	D93 I94 M97 D275 F276 A277 F281 K282 H283	D93-L279 HydrophobicContact CB-CD1 4.49Å; D93-L279 HydrophobicContact CB-CD2 4.49Å; I94-L279 HydrophobicContact CG1-CD2 4.01Å; I94-L279 HydrophobicContact CG1-CG 4.45Å; M97-L279 HydrophobicContact CG-CD2 3.69Å; D275-L279 PolarHBondContact O-N 2.99Å; F276-L279 WeakPolarHBondContact O-CA 3.08Å; F276-L279 WeakPolarHBondContact O-CB 3.38Å; F276-L279 PolarHBondContact O-N 3.49Å; A277-L279 PolarHBondContact O-N 3.37Å; L279-F281 VanDerWaalsContact C-N 3.27Å; L279-F281 PolarHBondContact O-N 3.35Å; L279-K282 WeakPolarHBondContact O-CB 3.09Å; L279-K282 PolarHBondContact O-N 3.5Å; L279-K282 VanDerWaalsContact O-N 3.13Å; L279-H283 PolarHBondContact O-CD2 3.11Å; L279-H283 PolarHBondContact O-N 3.01Å
280	M	97.6	Very high	95.7	Very high	0 Å²	0	34.7 Å²	34.7	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-60.4	-40.2	175.1	-65.3	-54.5	-63.1	0	0	111.1	L76 I94 V157 A162 F276 A277 K282 H283 L284	L76-M280 HydrophobicContact CD1-CE 3.71Å; L76-M280 WeakPolarHBondContact CD1-O 3.32Å; L76-M280 HydrophobicContact CD2-CE 3.71Å; L76-M280 HydrophobicContact CG-CE 4.19Å; I94-M280 HydrophobicContact CD1-SD 4.1Å; V157-M280 HydrophobicContact CG1-CE 4.07Å; V157-M280 HydrophobicContact CG2-CE 4.25Å; A162-M280 HydrophobicContact CB-CE 3.97Å; A162-M280 HydrophobicContact CB-SD 4Å; F276-M280 HydrophobicContact CD1-CG 3.95Å; F276-M280 HydrophobicContact CE1-CG 3.58Å; F276-M280 HydrophobicContact CE1-SD 3.87Å; F276-M280 HydrophobicContact CE2-SD 4.25Å; F276-M280 HydrophobicContact CZ-CG 3.91Å; F276-M280 HydrophobicContact CZ-SD 3.6Å; F276-M280 VanDerWaalsContact CZ-SD 3.6Å; F276-M280 WeakPolarHBondContact O-CG 3.44Å; F276-M280 PolarHBondContact O-N 3.32Å; A277-M280 PolarHBondContact O-N 2.84Å; M280-K282 VanDerWaalsContact C-N 3.34Å; M280-K282 PolarHBondContact O-N 3.22Å; M280-H283 PolarHBondContact O-N 3.21Å; M280-L284 PolarHBondContact O-N 3.21Å
281	F	97.4	Very high	95.9	Very high	0 Å²	0	42.4 Å²	42.4	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-62.1	-39.2	174.4	-170.6	-97.9	0	0	0	112.7	V229 V230 A277 C278 L279 H283 L284 K287 P288 V293 L339 F341	V229-F281 HydrophobicContact CG1-CB 3.94Å; V229-F281 HydrophobicContact CG1-CD2 4.33Å; V230-F281 HydrophobicContact CG2-CD2 3.74Å; V230-F281 HydrophobicContact CG2-CE2 3.43Å; V230-F281 VanDerWaalsContact CG2-CE2 3.43Å; V230-F281 HydrophobicContact CG2-CZ 4.17Å; A277-F281 WeakPolarHBondContact O-CB 3.3Å; A277-F281 PolarHBondContact O-N 2.91Å; C278-F281 WeakPolarHBondContact O-CB 3.48Å; C278-F281 PolarHBondContact O-N 3.46Å; L279-F281 VanDerWaalsContact C-N 3.27Å; L279-F281 PolarHBondContact O-N 3.35Å; F281-H283 VanDerWaalsContact C-N 3.31Å; F281-H283 PolarHBondContact O-N 2.97Å; F281-L284 HydrophobicContact CD2-CD1 4.01Å; F281-L284 WeakPolarHBondContact O-CB 3.14Å; F281-L284 PolarHBondContact O-N 2.95Å; F281-L284 VanDerWaalsContact O-N 3.17Å; F281-K287 HydrophobicContact CD1-CD 4.43Å; F281-K287 HydrophobicContact CE1-CD 3.84Å; F281-K287 HydrophobicContact CE1-CG 4.17Å; F281-K287 HydrophobicContact CZ-CB 4.07Å; F281-K287 HydrophobicContact CZ-CD 4.25Å; F281-K287 HydrophobicContact CZ-CG 4.13Å; F281-K287 VanDerWaalsContact O-CE 3.27Å; F281-K287 WeakPolarHBondContact O-CE 3.39Å; F281-P288 HydrophobicContact CE2-CG 3.71Å; F281-P288 HydrophobicContact CZ-CG 4.04Å; F281-V293 HydrophobicContact CZ-CG2 4.35Å; F281-L339 HydrophobicContact CB-CD2 3.84Å; F281-L339 HydrophobicContact CD1-CB 4.35Å; F281-L339 HydrophobicContact CD1-CD2 3.72Å; F281-L339 HydrophobicContact CD2-CD2 4.29Å; F281-L339 HydrophobicContact CE1-CB 4.41Å; F281-L339 HydrophobicContact CE1-CD2 4.36Å; F281-L339 WeakPolarHBondContact CE1-O 3.44Å; F281-L339 HydrophobicContact CG-CD2 3.69Å; F281-F341 AromaticContact CE1-CE2 3.65Å; F281-F341 HydrophobicContact CE1-CE2 3.65Å; F281-F341 HydrophobicContact CE1-CZ 4.07Å; F281-F341 AromaticContact CZ-CE2 3.78Å; F281-F341 HydrophobicContact CZ-CE2 3.78Å; F281-F341 AromaticContact CZ-CZ 3.96Å; F281-F341 HydrophobicContact CZ-CZ 3.96Å
282	K	97	Very high	96.1	Very high	117 Å²	117	42.9 Å²	42.9	51%	0.509	23%	0.23	S	C	.	.	H	α-helix	trans	-61	-40.1	176.7	-74.4	166.4	-173.8	167.3	0	112	C278 L279 M280 L284 K287 E338	C278-K282 WeakPolarHBondContact O-CG 3.14Å; C278-K282 PolarHBondContact O-N 3.4Å; L279-K282 WeakPolarHBondContact O-CB 3.09Å; L279-K282 PolarHBondContact O-N 3.5Å; L279-K282 VanDerWaalsContact O-N 3.13Å; M280-K282 VanDerWaalsContact C-N 3.34Å; M280-K282 PolarHBondContact O-N 3.22Å; K282-L284 PolarHBondContact O-N 2.96Å; K282-K287 PolarHBondContact O-NZ 3.49Å; K282-E338 WeakPolarHBondContact CE-O 3.21Å
283	H	96.3	Very high	96.3	Very high	51 Å²	51	42.5 Å²	42.5	24%	0.236	23%	0.228	C	C	.	.	T	Hydrogen-bonded Turn	trans	-71.7	-8	177.6	-81.4	-71	0	0	0	114.7	L76 Y91 D93 L279 M280 F281	L76-H283 HydrophobicContact CD1-CB 3.8Å; L76-H283 HydrophobicContact CD2-CB 3.98Å; L76-H283 HydrophobicContact CG-CB 4.08Å; Y91-H283 AromaticContact CD1-CE1 3.69Å; Y91-H283 AromaticContact CE1-CE1 3.9Å; Y91-H283 AromaticContact CE1-ND1 3.82Å; D93-H283 IonicContact OD1-NE2 2.64Å; D93-H283 IonicContact OD2-CD2 3.13Å; D93-H283 IonicContact OD2-CE1 3.26Å; D93-H283 PolarHBondContact OD2-CE1 3.07Å; D93-H283 IonicContact OD2-NE2 3.58Å; D93-H283 PolarHBondContact OD2-NE2 3.17Å; L279-H283 PolarHBondContact O-CD2 3.11Å; L279-H283 PolarHBondContact O-N 3.01Å; M280-H283 PolarHBondContact O-N 3.21Å; F281-H283 VanDerWaalsContact C-N 3.31Å; F281-H283 PolarHBondContact O-N 2.97Å
284	L	95.5	Very high	96.3	Very high	6 Å²	6	44 Å²	44	3%	0.031	24%	0.237	C	C	.	.			trans	-72.7	136.5	172.9	-69	170.6	0	0	0	112.1	E74 L76 Y225 G226 M280 F281 K282 K287	E74-L284 HydrophobicContact CG-CD2 4.39Å; L76-L284 HydrophobicContact CD1-CD2 4Å; L76-L284 HydrophobicContact CD1-CG 4.32Å; Y225-L284 HydrophobicContact CD1-CD1 4.1Å; Y225-L284 HydrophobicContact CD1-CD2 3.55Å; Y225-L284 HydrophobicContact CD1-CG 4.34Å; Y225-L284 HydrophobicContact CE1-CD1 4.33Å; Y225-L284 HydrophobicContact CE1-CD2 3.82Å; Y225-L284 HydrophobicContact CE1-CG 4.39Å; G226-L284 VanDerWaalsContact CA-CD1 3.44Å; M280-L284 PolarHBondContact O-N 3.21Å; F281-L284 HydrophobicContact CD2-CD1 4.01Å; F281-L284 WeakPolarHBondContact O-CB 3.14Å; F281-L284 PolarHBondContact O-N 2.95Å; F281-L284 VanDerWaalsContact O-N 3.17Å; K282-L284 PolarHBondContact O-N 2.96Å; L284-K287 HydrophobicContact CB-CG 4.18Å; L284-K287 PolarHBondContact O-NZ 3.1Å
285	V	94.5	Very high	96.4	Very high	94 Å²	94	50.5 Å²	50.5	57%	0.57	27%	0.265	S	S	*	.	S	Bend	trans	-80.4	-53.7	173.5	179.9	0	0	0	0	109.4	E74 P75 K287	E74-V285 PolarHBondContact OE2-N 2.85Å; P75-V285 HydrophobicContact CG-CG2 4.16Å; V285-K287 PolarHBondContact O-N 3.38Å
286	N	93.3	Very high	96.5	Very high	78 Å²	78	47.9 Å²	47.9	42%	0.417	25%	0.25	S	S	.	.	S	Bend	trans	-94.1	81	-179.2	-55.6	-71.5	0	0	0	110.2	S70 E74	S70-N286 PolarHBondContact O-ND2 3.06Å; E74-N286 WeakPolarHBondContact OE1-CA 3.44Å; E74-N286 WeakPolarHBondContact OE1-CB 3.45Å; E74-N286 PolarHBondContact OE1-N 3.1Å; E74-N286 PolarHBondContact OE1-ND2 2.91Å
287	K	95.1	Very high	96.5	Very high	94 Å²	94	47.9 Å²	47.9	41%	0.409	25%	0.25	S	S	.	.	P	Polyproline II helix	trans	-72.5	142.7	176.8	-66.2	177.9	172.7	71.4	0	110.9	F281 K282 L284 V285	F281-K287 HydrophobicContact CD1-CD 4.43Å; F281-K287 HydrophobicContact CE1-CD 3.84Å; F281-K287 HydrophobicContact CE1-CG 4.17Å; F281-K287 HydrophobicContact CZ-CB 4.07Å; F281-K287 HydrophobicContact CZ-CD 4.25Å; F281-K287 HydrophobicContact CZ-CG 4.13Å; F281-K287 VanDerWaalsContact O-CE 3.27Å; F281-K287 WeakPolarHBondContact O-CE 3.39Å; K282-K287 PolarHBondContact O-NZ 3.49Å; L284-K287 HydrophobicContact CB-CG 4.18Å; L284-K287 PolarHBondContact O-NZ 3.1Å; V285-K287 PolarHBondContact O-N 3.38Å
288	P	95.4	Very high	96.6	Very high	11 Å²	11	53.3 Å²	53.3	7%	0.071	27%	0.271	C	S	.	.	P	Polyproline II helix	trans	-60.7	152.3	172.6	25.4	-34.1	0	0	0	111.5	E227 F281 V293	E227-P288 HydrophobicContact CG-CB 3.88Å; E227-P288 HydrophobicContact CG-CG 4.41Å; F281-P288 HydrophobicContact CE2-CG 3.71Å; F281-P288 HydrophobicContact CZ-CG 4.04Å; P288-V293 HydrophobicContact CB-CG2 4.25Å; P288-V293 HydrophobicContact CG-CG2 3.72Å
289	P	96	Very high	96.6	Very high	85 Å²	85	56.1 Å²	56.1	55%	0.552	29%	0.285	S	S	*	.	P	Polyproline II helix	trans	-57.4	146.7	177.1	-23.5	33.4	0	0	0	112.3	E291 T292 V293	P289-E291 PolarHBondContact O-N 3.27Å; P289-E291 VanDerWaalsContact O-N 3.13Å; P289-T292 WeakPolarHBondContact O-CB 3.34Å; P289-T292 PolarHBondContact O-N 2.96Å; P289-V293 PolarHBondContact O-N 2.69Å; P289-V293 VanDerWaalsContact O-N 3.09Å
290	A	96.3	Very high	96.5	Very high	51 Å²	51	55 Å²	55	42%	0.421	28%	0.28	S	S	.	.	H	α-helix	trans	-55.1	-34.5	179.4	0	0	0	0	0	113.1	V293 T294 F341	A290-V293 PolarHBondContact O-N 3.45Å; A290-T294 VanDerWaalsContact O-CB 3.26Å; A290-T294 WeakPolarHBondContact O-CB 3.45Å; A290-T294 PolarHBondContact O-N 3.3Å; A290-T294 PolarHBondContact O-OG1 3.49Å; A290-F341 HydrophobicContact CB-CD1 3.62Å; A290-F341 HydrophobicContact CB-CE1 3.59Å
291	E	97.1	Very high	96.5	Very high	165 Å²	165	55 Å²	55	77%	0.771	28%	0.28	S	S	*	.	H	α-helix	trans	-63.6	-43.9	176.1	-173.8	178.8	179.1	0	0	111.9	P289 T294 K295	P289-E291 PolarHBondContact O-N 3.27Å; P289-E291 VanDerWaalsContact O-N 3.13Å; E291-T294 PolarHBondContact O-N 3.25Å; E291-K295 WeakPolarHBondContact O-CB 3.38Å; E291-K295 PolarHBondContact O-N 2.99Å
292	T	96.3	Very high	96.5	Very high	40 Å²	40	59.9 Å²	59.9	25%	0.245	30%	0.303	C	S	.	.	H	α-helix	trans	-62.9	-48.3	176.2	-57.4	0	0	0	0	111	E227 P289 T294 K295 I296	E227-T292 HydrophobicContact CG-CG2 3.93Å; E227-T292 WeakPolarHBondContact OE1-CG2 3.48Å; P289-T292 WeakPolarHBondContact O-CB 3.34Å; P289-T292 PolarHBondContact O-N 2.96Å; T292-T294 VanDerWaalsContact C-N 3.35Å; T292-T294 PolarHBondContact O-N 3.15Å; T292-K295 WeakPolarHBondContact O-CB 3.38Å; T292-K295 PolarHBondContact O-N 3.21Å; T292-I296 HydrophobicContact CG2-CD1 4.16Å; T292-I296 WeakPolarHBondContact O-CG1 3.34Å; T292-I296 PolarHBondContact O-N 2.75Å
293	V	97.4	Very high	96.4	Very high	0 Å²	0	55.1 Å²	55.1	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-58	-49.6	177.3	176.5	0	0	0	0	110.5	V230 F281 P288 P289 A290 K295 I296 I297 L336 L339 F341	V230-V293 HydrophobicContact CG1-CG1 3.89Å; V230-V293 HydrophobicContact CG2-CG1 4.3Å; V230-V293 HydrophobicContact CG2-CG2 4.11Å; F281-V293 HydrophobicContact CZ-CG2 4.35Å; P288-V293 HydrophobicContact CB-CG2 4.25Å; P288-V293 HydrophobicContact CG-CG2 3.72Å; P289-V293 PolarHBondContact O-N 2.69Å; P289-V293 VanDerWaalsContact O-N 3.09Å; A290-V293 PolarHBondContact O-N 3.45Å; V293-K295 VanDerWaalsContact C-N 3.28Å; V293-K295 PolarHBondContact O-N 3.11Å; V293-I296 PolarHBondContact O-N 3.29Å; V293-I297 HydrophobicContact CG1-CG1 4.46Å; V293-I297 WeakPolarHBondContact O-CG1 3.39Å; V293-I297 PolarHBondContact O-N 2.67Å; V293-L336 HydrophobicContact CG1-CD2 4.19Å; V293-L339 HydrophobicContact CG1-CD1 4.22Å; V293-F341 HydrophobicContact CB-CD2 4.43Å; V293-F341 HydrophobicContact CB-CE2 4.05Å; V293-F341 HydrophobicContact CB-CZ 4.15Å; V293-F341 HydrophobicContact CG1-CD2 3.79Å; V293-F341 HydrophobicContact CG1-CE2 3.68Å; V293-F341 HydrophobicContact CG1-CG 4.49Å; V293-F341 HydrophobicContact CG1-CZ 4.3Å; V293-F341 HydrophobicContact CG2-CE1 4.46Å; V293-F341 HydrophobicContact CG2-CE2 3.82Å; V293-F341 HydrophobicContact CG2-CZ 3.69Å
294	T	97.3	Very high	96.4	Very high	35 Å²	35	52.7 Å²	52.7	22%	0.215	27%	0.271	C	S	.	.	H	α-helix	trans	-58.1	-42.2	178.2	-60	0	0	0	0	111.2	A290 E291 T292 I297 R298 V344	A290-T294 VanDerWaalsContact O-CB 3.26Å; A290-T294 WeakPolarHBondContact O-CB 3.45Å; A290-T294 PolarHBondContact O-N 3.3Å; A290-T294 PolarHBondContact O-OG1 3.49Å; E291-T294 PolarHBondContact O-N 3.25Å; T292-T294 VanDerWaalsContact C-N 3.35Å; T292-T294 PolarHBondContact O-N 3.15Å; T294-I297 PolarHBondContact O-N 3.06Å; T294-R298 HydrophobicContact CG2-CG 4.19Å; T294-R298 WeakPolarHBondContact O-CB 3.4Å; T294-R298 VanDerWaalsContact O-CG 3.25Å; T294-R298 WeakPolarHBondContact O-CG 3.41Å; T294-R298 PolarHBondContact O-N 3.3Å; T294-V344 HydrophobicContact CG2-CG2 3.77Å
295	K	97.6	Very high	96.4	Very high	144 Å²	144	53.8 Å²	53.8	63%	0.626	28%	0.276	S	S	*	.	H	α-helix	trans	-62.2	-46.7	177.6	-175.7	178.5	178.6	-178.3	0	111.5	E291 T292 V293 I297 R298 N299	E291-K295 WeakPolarHBondContact O-CB 3.38Å; E291-K295 PolarHBondContact O-N 2.99Å; T292-K295 WeakPolarHBondContact O-CB 3.38Å; T292-K295 PolarHBondContact O-N 3.21Å; V293-K295 VanDerWaalsContact C-N 3.28Å; V293-K295 PolarHBondContact O-N 3.11Å; K295-I297 PolarHBondContact O-N 3.15Å; K295-R298 PolarHBondContact O-N 3.06Å; K295-N299 PolarHBondContact O-N 3.49Å; K295-N299 PolarHBondContact O-ND2 2.85Å
296	I	97.3	Very high	96.4	Very high	6 Å²	6	53 Å²	53	3%	0.031	27%	0.266	C	S	.	.	H	α-helix	trans	-58.1	-50.3	178.6	-64.4	169.8	0	0	0	110.1	W213 W217 E227 V230 A231 T292 V293 R298 N299 A300	W213-I296 HydrophobicContact CH2-CG2 4.06Å; W213-I296 HydrophobicContact CZ2-CG2 3.86Å; W217-I296 HydrophobicContact CH2-CD1 3.67Å; W217-I296 HydrophobicContact CH2-CG1 3.7Å; W217-I296 HydrophobicContact CZ2-CD1 4.08Å; W217-I296 HydrophobicContact CZ2-CG1 3.69Å; W217-I296 HydrophobicContact CZ2-CG2 4.33Å; W217-I296 HydrophobicContact CZ3-CD1 4.23Å; E227-I296 HydrophobicContact CB-CD1 4.2Å; E227-I296 HydrophobicContact CG-CD1 4.44Å; V230-I296 HydrophobicContact CB-CD1 4.38Å; V230-I296 HydrophobicContact CG1-CB 4.11Å; V230-I296 HydrophobicContact CG1-CD1 4.18Å; V230-I296 HydrophobicContact CG1-CG2 3.95Å; A231-I296 HydrophobicContact CB-CG2 4.09Å; T292-I296 HydrophobicContact CG2-CD1 4.16Å; T292-I296 WeakPolarHBondContact O-CG1 3.34Å; T292-I296 PolarHBondContact O-N 2.75Å; V293-I296 PolarHBondContact O-N 3.29Å; I296-R298 PolarHBondContact O-N 2.95Å; I296-N299 PolarHBondContact O-N 3.08Å; I296-A300 PolarHBondContact O-N 2.79Å
297	I	97.7	Very high	96.5	Very high	1 Å²	1	49.5 Å²	49.5	1%	0.005	25%	0.247	C	C	.	.	H	α-helix	trans	-62.7	-44.3	-179.8	-63.1	-54.7	0	0	0	111.9	V230 A234 I238 V293 T294 K295 N299 A300 V301 A332 L335 L336	V230-I297 HydrophobicContact CG1-CD1 4.11Å; V230-I297 HydrophobicContact CG1-CG1 4.37Å; A234-I297 HydrophobicContact CB-CD1 3.95Å; I238-I297 HydrophobicContact CD1-CD1 4.09Å; I238-I297 HydrophobicContact CD1-CG2 3.85Å; V293-I297 HydrophobicContact CG1-CG1 4.46Å; V293-I297 WeakPolarHBondContact O-CG1 3.39Å; V293-I297 PolarHBondContact O-N 2.67Å; T294-I297 PolarHBondContact O-N 3.06Å; K295-I297 PolarHBondContact O-N 3.15Å; I297-N299 PolarHBondContact O-N 3.11Å; I297-A300 PolarHBondContact O-N 3.3Å; I297-V301 HydrophobicContact CG2-CG2 4.46Å; I297-V301 WeakPolarHBondContact O-CG2 3.46Å; I297-V301 PolarHBondContact O-N 2.89Å; I297-A332 HydrophobicContact CG2-CB 3.87Å; I297-L335 HydrophobicContact CD1-CD2 3.72Å; I297-L335 HydrophobicContact CD1-CG 4.31Å; I297-L336 HydrophobicContact CB-CD2 4.32Å; I297-L336 HydrophobicContact CG1-CD2 3.93Å; I297-L336 HydrophobicContact CG1-CG 4.39Å; I297-L336 HydrophobicContact CG2-CD1 4.24Å; I297-L336 HydrophobicContact CG2-CD2 4.43Å; I297-L336 HydrophobicContact CG2-CG 4.16Å
298	R	97.9	Very high	96.5	Very high	116 Å²	116	45 Å²	45	44%	0.438	23%	0.228	S	C	.	.	H	α-helix	trans	-62.1	-42.6	178.2	-73.7	-176.9	72.4	155.9	5.3	112.5	T294 K295 I296 A300 V301 E302	T294-R298 HydrophobicContact CG2-CG 4.19Å; T294-R298 WeakPolarHBondContact O-CB 3.4Å; T294-R298 VanDerWaalsContact O-CG 3.25Å; T294-R298 WeakPolarHBondContact O-CG 3.41Å; T294-R298 PolarHBondContact O-N 3.3Å; K295-R298 PolarHBondContact O-N 3.06Å; I296-R298 PolarHBondContact O-N 2.95Å; R298-A300 VanDerWaalsContact C-N 3.29Å; R298-A300 PolarHBondContact O-N 2.61Å; R298-V301 PolarHBondContact O-N 3.47Å; R298-E302 WeakPolarHBondContact O-CG 3.48Å; R298-E302 PolarHBondContact O-N 2.96Å
299	N	97.1	Very high	96.3	Very high	61 Å²	61	45.1 Å²	45.1	33%	0.326	23%	0.228	S	C	.	.	H	α-helix	trans	-61.4	-40.8	175.5	-80.5	-94.6	0	0	0	111	K295 I296 I297 E302 I303	K295-N299 PolarHBondContact O-N 3.49Å; K295-N299 PolarHBondContact O-ND2 2.85Å; I296-N299 PolarHBondContact O-N 3.08Å; I297-N299 PolarHBondContact O-N 3.11Å; N299-E302 PolarHBondContact O-N 3.36Å; N299-I303 WeakPolarHBondContact O-CD1 3.48Å; N299-I303 VanDerWaalsContact O-CG1 3.27Å; N299-I303 WeakPolarHBondContact O-CG1 3.46Å; N299-I303 PolarHBondContact O-N 3.36Å; N299-I303 VanDerWaalsContact O-N 3.17Å
300	A	96.7	Very high	95.9	Very high	0 Å²	0	46.3 Å²	46.3	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-63.7	-43.6	176.7	0	0	0	0	0	112.2	W213 A234 I238 F239 I296 I297 R298 I303 E304	W213-A300 HydrophobicContact CH2-CB 4.31Å; W213-A300 HydrophobicContact CZ2-CB 4.18Å; A234-A300 HydrophobicContact CB-CB 3.91Å; I238-A300 HydrophobicContact CD1-CB 4.38Å; I238-A300 HydrophobicContact CG2-CB 4.36Å; F239-A300 HydrophobicContact CD1-CB 4.29Å; F239-A300 HydrophobicContact CE1-CB 3.74Å; F239-A300 WeakPolarHBondContact CE1-O 3.45Å; F239-A300 HydrophobicContact CZ-CB 4.31Å; I296-A300 PolarHBondContact O-N 2.79Å; I297-A300 PolarHBondContact O-N 3.3Å; R298-A300 VanDerWaalsContact C-N 3.29Å; R298-A300 PolarHBondContact O-N 2.61Å; A300-I303 PolarHBondContact O-N 3.03Å; A300-E304 WeakPolarHBondContact O-CB 3.09Å; A300-E304 PolarHBondContact O-N 2.99Å
301	V	97.7	Very high	95.5	Very high	1 Å²	1	45.8 Å²	45.8	1%	0.006	23%	0.226	C	C	.	.	H	α-helix	trans	-60.7	-46.8	176.3	170.2	0	0	0	0	111.9	I238 I297 R298 I303 E304 Q305 I328 E329 A332 Y345	I238-V301 HydrophobicContact CD1-CG2 4.29Å; I238-V301 HydrophobicContact CG2-CG2 4.3Å; I297-V301 HydrophobicContact CG2-CG2 4.46Å; I297-V301 WeakPolarHBondContact O-CG2 3.46Å; I297-V301 PolarHBondContact O-N 2.89Å; R298-V301 PolarHBondContact O-N 3.47Å; V301-I303 VanDerWaalsContact C-N 3.32Å; V301-I303 PolarHBondContact O-N 3.42Å; V301-E304 PolarHBondContact O-N 3.39Å; V301-Q305 HydrophobicContact CG1-CG 4.13Å; V301-Q305 WeakPolarHBondContact O-CB 3.43Å; V301-Q305 VanDerWaalsContact O-CG 3.3Å; V301-Q305 WeakPolarHBondContact O-CG 3.29Å; V301-Q305 PolarHBondContact O-N 2.82Å; V301-I328 HydrophobicContact CB-CG2 4.38Å; V301-I328 HydrophobicContact CG1-CG2 3.99Å; V301-I328 HydrophobicContact CG2-CG2 4.26Å; V301-E329 HydrophobicContact CG1-CG 4.34Å; V301-A332 HydrophobicContact CG2-CB 3.32Å; V301-Y345 WeakPolarHBondContact CB-OH 3.49Å; V301-Y345 HydrophobicContact CG1-CE1 4.47Å; V301-Y345 HydrophobicContact CG1-CE2 4.38Å; V301-Y345 WeakPolarHBondContact CG1-OH 3.47Å; V301-Y345 HydrophobicContact CG2-CE2 4.05Å
302	E	96.8	Very high	95.3	Very high	102 Å²	102	38.1 Å²	38.1	48%	0.477	19%	0.19	S	C	.	.	H	α-helix	trans	-60	-43.3	-179.5	-73.6	168.8	-167.4	0	0	111.5	R298 N299 E306	R298-E302 WeakPolarHBondContact O-CG 3.48Å; R298-E302 PolarHBondContact O-N 2.96Å; N299-E302 PolarHBondContact O-N 3.36Å; E302-E306 WeakPolarHBondContact O-CB 3.45Å; E302-E306 PolarHBondContact O-N 3.27Å; E302-E306 VanDerWaalsContact O-N 3.07Å
303	I	95.4	Very high	95.2	Very high	16 Å²	16	37 Å²	37	8%	0.082	18%	0.184	C	C	.	.	H	α-helix	trans	-64.9	-42.9	176.5	-66.1	168	0	0	0	111.1	K209 K210 W213 F239 N299 A300 V301 E306 F307	K209-I303 HydrophobicContact CD-CG1 4.5Å; K210-I303 HydrophobicContact CB-CG2 4.45Å; K210-I303 HydrophobicContact CD-CG2 4.49Å; K210-I303 HydrophobicContact CG-CG2 3.4Å; K210-I303 VanDerWaalsContact CG-CG2 3.4Å; W213-I303 HydrophobicContact CB-CD1 3.98Å; W213-I303 VanDerWaalsContact CD1-CD1 3.48Å; W213-I303 HydrophobicContact CG-CD1 3.77Å; F239-I303 HydrophobicContact CE1-CB 4.08Å; F239-I303 HydrophobicContact CE1-CG2 4.05Å; F239-I303 HydrophobicContact CZ-CB 4.49Å; F239-I303 HydrophobicContact CZ-CD1 4.26Å; F239-I303 HydrophobicContact CZ-CG2 4.29Å; N299-I303 WeakPolarHBondContact O-CD1 3.48Å; N299-I303 VanDerWaalsContact O-CG1 3.27Å; N299-I303 WeakPolarHBondContact O-CG1 3.46Å; N299-I303 PolarHBondContact O-N 3.36Å; N299-I303 VanDerWaalsContact O-N 3.17Å; A300-I303 PolarHBondContact O-N 3.03Å; V301-I303 VanDerWaalsContact C-N 3.32Å; V301-I303 PolarHBondContact O-N 3.42Å; I303-E306 PolarHBondContact O-N 2.77Å; I303-F307 WeakPolarHBondContact O-CB 3.34Å; I303-F307 PolarHBondContact O-N 3.5Å
304	E	96.1	Very high	95.1	Very high	0 Å²	0	37 Å²	37	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-66.3	-41.4	179.9	-177.2	61.3	-166.7	0	0	112.3	K210 I238 F239 G242 A300 V301 F307 L308 I328	K210-E304 WeakPolarHBondContact CE-OE2 3.31Å; K210-E304 IonicContact NZ-OE1 2.75Å; K210-E304 IonicContact NZ-OE2 2.69Å; K210-E304 PolarHBondContact NZ-OE2 2.95Å; I238-E304 HydrophobicContact CG2-CB 4.18Å; I238-E304 HydrophobicContact CG2-CG 4.39Å; F239-E304 WeakPolarHBondContact CA-OE2 3.33Å; F239-E304 VanDerWaalsContact O-OE2 3.05Å; G242-E304 PolarHBondContact N-OE1 3.45Å; A300-E304 WeakPolarHBondContact O-CB 3.09Å; A300-E304 PolarHBondContact O-N 2.99Å; V301-E304 PolarHBondContact O-N 3.39Å; E304-F307 PolarHBondContact O-N 2.89Å; E304-L308 PolarHBondContact O-N 3.43Å; E304-L308 VanDerWaalsContact O-N 3.14Å; E304-L308 VanDerWaalsContact OE1-CD1 3.26Å; E304-L308 WeakPolarHBondContact OE1-CD1 3.33Å; E304-I328 HydrophobicContact CB-CD1 4.41Å; E304-I328 HydrophobicContact CB-CG2 3.97Å; E304-I328 HydrophobicContact CG-CB 4.47Å; E304-I328 HydrophobicContact CG-CD1 3.68Å; E304-I328 HydrophobicContact CG-CG1 3.8Å; E304-I328 HydrophobicContact CG-CG2 3.77Å
305	Q	96.4	Very high	95	Very high	29 Å²	29	42 Å²	42	14%	0.136	20%	0.202	C	C	.	.	H	α-helix	trans	-62.6	-47.5	175.9	-72.6	-175.9	-12.2	0	0	111.2	V301 F307 L308 T309 K325 I328 E329	V301-Q305 HydrophobicContact CG1-CG 4.13Å; V301-Q305 WeakPolarHBondContact O-CB 3.43Å; V301-Q305 VanDerWaalsContact O-CG 3.3Å; V301-Q305 WeakPolarHBondContact O-CG 3.29Å; V301-Q305 PolarHBondContact O-N 2.82Å; Q305-F307 VanDerWaalsContact C-N 3.3Å; Q305-F307 PolarHBondContact O-N 3.22Å; Q305-L308 PolarHBondContact O-N 2.94Å; Q305-T309 WeakPolarHBondContact O-CB 3.43Å; Q305-T309 WeakPolarHBondContact O-CG2 3.23Å; Q305-T309 PolarHBondContact O-N 3.13Å; Q305-T309 PolarHBondContact O-OG1 2.99Å; Q305-K325 HydrophobicContact CB-CG 4.18Å; Q305-K325 HydrophobicContact CG-CB 4.23Å; Q305-K325 HydrophobicContact CG-CG 3.93Å; Q305-K325 PolarHBondContact NE2-O 2.83Å; Q305-I328 HydrophobicContact CB-CD1 4.49Å; Q305-I328 HydrophobicContact CG-CB 4.41Å; Q305-I328 HydrophobicContact CG-CD1 3.86Å; Q305-I328 HydrophobicContact CG-CG2 4.35Å; Q305-E329 PolarHBondContact NE2-OE1 2.91Å
306	E	94.6	Very high	94.8	Very high	77 Å²	77	36.8 Å²	36.8	36%	0.36	18%	0.181	S	C	.	.	H	α-helix	trans	-59.1	-42.1	176	-179.6	-177.1	152.8	0	0	111.6	K209 E302 I303 L308 D310 A311	K209-E306 VanDerWaalsContact NZ-CD 3.35Å; K209-E306 IonicContact NZ-OE1 2.56Å; K209-E306 PolarHBondContact NZ-OE1 3.13Å; K209-E306 IonicContact NZ-OE2 2.9Å; K209-E306 PolarHBondContact NZ-OE2 3.35Å; E302-E306 WeakPolarHBondContact O-CB 3.45Å; E302-E306 PolarHBondContact O-N 3.27Å; E302-E306 VanDerWaalsContact O-N 3.07Å; I303-E306 PolarHBondContact O-N 2.77Å; E306-L308 VanDerWaalsContact C-N 3.34Å; E306-L308 PolarHBondContact O-N 2.99Å; E306-D310 HydrophobicContact CG-CB 4.4Å; E306-D310 WeakPolarHBondContact O-CB 3.48Å; E306-D310 PolarHBondContact O-N 2.86Å; E306-A311 PolarHBondContact O-N 3.48Å
307	F	93.7	Very high	94.8	Very high	5 Å²	5	36.6 Å²	36.6	2%	0.022	18%	0.18	C	C	.	.	I	π-helix	trans	-57.8	-45.8	178	-179.7	-107.9	0	0	0	111.8	F137 C206 V207 K210 I303 E304 Q305 L312	F137-F307 HydrophobicContact CB-CZ 4.11Å; F137-F307 HydrophobicContact CD1-CE1 4.36Å; F137-F307 HydrophobicContact CD1-CZ 4.2Å; F137-F307 HydrophobicContact CD2-CZ 4.46Å; F137-F307 HydrophobicContact CG-CE2 4.48Å; F137-F307 AromaticContact CG-CZ 3.98Å; F137-F307 HydrophobicContact CG-CZ 3.98Å; C206-F307 HydrophobicContact CB-CD2 4.02Å; C206-F307 HydrophobicContact CB-CE2 4.35Å; V207-F307 HydrophobicContact CG2-CE2 4.47Å; K210-F307 HydrophobicContact CD-CD2 4.48Å; K210-F307 HydrophobicContact CD-CG 4.37Å; I303-F307 WeakPolarHBondContact O-CB 3.34Å; I303-F307 PolarHBondContact O-N 3.5Å; E304-F307 PolarHBondContact O-N 2.89Å; Q305-F307 VanDerWaalsContact C-N 3.3Å; Q305-F307 PolarHBondContact O-N 3.22Å; F307-L312 HydrophobicContact CZ-CB 4.49Å; F307-L312 HydrophobicContact CZ-CD2 4.06Å; F307-L312 CarbonylContact O-C 3.58Å; F307-L312 WeakPolarHBondContact O-CA 3.47Å; F307-L312 PolarHBondContact O-N 2.64Å
308	L	95.2	Very high	94.7	Very high	0 Å²	0	39.2 Å²	39.2	0%	0	21%	0.208	C	C	.	.	I	π-helix	trans	-95.5	-7.1	-173.1	-68.7	176.9	0	0	0	115.7	F130 E304 Q305 E306 P313 V314 M324 I328	F130-L308 HydrophobicContact CZ-CD2 4.35Å; E304-L308 PolarHBondContact O-N 3.43Å; E304-L308 VanDerWaalsContact O-N 3.14Å; E304-L308 VanDerWaalsContact OE1-CD1 3.26Å; E304-L308 WeakPolarHBondContact OE1-CD1 3.33Å; Q305-L308 PolarHBondContact O-N 2.94Å; E306-L308 VanDerWaalsContact C-N 3.34Å; E306-L308 PolarHBondContact O-N 2.99Å; L308-P313 CarbonylContact O-C 3.52Å; L308-P313 WeakPolarHBondContact O-CA 3.35Å; L308-V314 HydrophobicContact CB-CG1 3.94Å; L308-V314 HydrophobicContact CD2-CG1 3.97Å; L308-V314 HydrophobicContact CG-CG1 4.38Å; L308-V314 PolarHBondContact O-N 3.3Å; L308-M324 HydrophobicContact CB-CG 3.96Å; L308-M324 HydrophobicContact CD1-CE 4.32Å; L308-M324 HydrophobicContact CD1-CG 3.93Å; L308-M324 HydrophobicContact CD1-SD 3.89Å; L308-I328 HydrophobicContact CD1-CD1 4.35Å
309	T	92.1	Very high	94.6	Very high	13 Å²	13	34.4 Å²	34.4	8%	0.08	19%	0.19	C	C	.	.	I	π-helix	trans	-112.7	-27.3	176	72.5	0	0	0	0	114.2	Q305 P313 C321 K325	Q305-T309 WeakPolarHBondContact O-CB 3.43Å; Q305-T309 WeakPolarHBondContact O-CG2 3.23Å; Q305-T309 PolarHBondContact O-N 3.13Å; Q305-T309 PolarHBondContact O-OG1 2.99Å; T309-P313 WeakPolarHBondContact O-CG 3.35Å; T309-C321 HydrophobicContact CG2-CB 3.73Å; T309-K325 HydrophobicContact CG2-CD 4.16Å; T309-K325 HydrophobicContact CG2-CG 3.72Å; T309-K325 WeakPolarHBondContact OG1-CE 3.43Å
310	D	88.4	Confident	94.6	Very high	110 Å²	110	35.1 Å²	35.1	59%	0.588	19%	0.194	S	C	*	.	I	π-helix	trans	-115.9	-55.2	-171.4	-57	-9.4	0	0	0	110.6	E306 P313	E306-D310 HydrophobicContact CG-CB 4.4Å; E306-D310 WeakPolarHBondContact O-CB 3.48Å; E306-D310 PolarHBondContact O-N 2.86Å; D310-P313 WeakPolarHBondContact O-CG 3.38Å
311	A	87.8	Confident	94.7	Very high	41 Å²	41	36.5 Å²	36.5	34%	0.339	20%	0.203	S	C	.	.	I	π-helix	trans	-77.9	-47.1	-175	0	0	0	0	0	114.1	C206 E306	C206-A311 HydrophobicContact CB-CB 3.22Å; E306-A311 PolarHBondContact O-N 3.48Å
312	L	91	Very high	94.6	Very high	3 Å²	3	41.5 Å²	41.5	2%	0.016	23%	0.23	C	C	.	.	S	Bend	trans	-128.4	74.6	175.4	-165.8	63.6	0	0	0	109.1	Y129 F130 H133 V134 F307 V314 L316	Y129-L312 HydrophobicContact CD1-CD1 4.1Å; Y129-L312 HydrophobicContact CE1-CD1 3.7Å; F130-L312 HydrophobicContact CD2-CD1 4.3Å; F130-L312 HydrophobicContact CD2-CD2 4.29Å; F130-L312 HydrophobicContact CD2-CG 3.76Å; F130-L312 HydrophobicContact CE2-CD2 4.34Å; F130-L312 HydrophobicContact CE2-CG 3.97Å; F130-L312 WeakPolarHBondContact CE2-O 3.47Å; H133-L312 HydrophobicContact CB-CD1 3.75Å; H133-L312 HydrophobicContact CB-CD2 3.65Å; H133-L312 HydrophobicContact CB-CG 4.37Å; V134-L312 HydrophobicContact CG2-CD2 3.6Å; F307-L312 HydrophobicContact CZ-CB 4.49Å; F307-L312 HydrophobicContact CZ-CD2 4.06Å; F307-L312 CarbonylContact O-C 3.58Å; F307-L312 WeakPolarHBondContact O-CA 3.47Å; F307-L312 PolarHBondContact O-N 2.64Å; L312-V314 PolarHBondContact O-N 2.85Å; L312-L316 HydrophobicContact CD1-CD1 4.35Å
313	P	94.3	Very high	94.7	Very high	17 Å²	17	40.1 Å²	40.1	11%	0.11	23%	0.225	C	C	.	.			trans	-64.3	126.1	-168.4	-26.6	38.7	0	0	0	112.8	L308 T309 D310 K315 L316	L308-P313 CarbonylContact O-C 3.52Å; L308-P313 WeakPolarHBondContact O-CA 3.35Å; T309-P313 WeakPolarHBondContact O-CG 3.35Å; D310-P313 WeakPolarHBondContact O-CG 3.38Å; P313-K315 HydrophobicContact CB-CD 4.04Å; P313-K315 HydrophobicContact CB-CG 3.67Å; P313-K315 PolarHBondContact O-N 3.4Å; P313-L316 VanDerWaalsContact O-CB 3.32Å; P313-L316 WeakPolarHBondContact O-CB 3.24Å; P313-L316 WeakPolarHBondContact O-CD1 3.48Å; P313-L316 WeakPolarHBondContact O-CG 3.14Å; P313-L316 PolarHBondContact O-N 3.18Å
314	V	95.1	Very high	94.8	Very high	0 Å²	0	39.4 Å²	39.4	0%	0	22%	0.221	C	C	.	.	G	3₁₀ helix	trans	-62.5	-12.4	177.6	-63.6	0	0	0	0	114.1	F130 L308 L312 L316 I317 G318 M319 M324	F130-V314 HydrophobicContact CE2-CB 4.42Å; F130-V314 HydrophobicContact CE2-CG1 3.93Å; F130-V314 HydrophobicContact CZ-CG1 3.98Å; L308-V314 HydrophobicContact CB-CG1 3.94Å; L308-V314 HydrophobicContact CD2-CG1 3.97Å; L308-V314 HydrophobicContact CG-CG1 4.38Å; L308-V314 PolarHBondContact O-N 3.3Å; L312-V314 PolarHBondContact O-N 2.85Å; V314-L316 PolarHBondContact O-N 3.09Å; V314-I317 WeakPolarHBondContact O-CG1 3.42Å; V314-I317 PolarHBondContact O-N 3.15Å; V314-G318 PolarHBondContact O-N 2.81Å; V314-M319 HydrophobicContact CB-CB 3.93Å; V314-M319 HydrophobicContact CB-SD 4.49Å; V314-M319 HydrophobicContact CG2-CB 3.95Å; V314-M319 PolarHBondContact O-N 3.46Å; V314-M319 VanDerWaalsContact O-N 3.1Å; V314-M324 HydrophobicContact CG1-CE 3.86Å; V314-M324 HydrophobicContact CG1-CG 4.2Å; V314-M324 HydrophobicContact CG2-CB 3.93Å; V314-M324 HydrophobicContact CG2-CG 4.35Å
315	K	95.8	Very high	94.9	Very high	140 Å²	140	42.4 Å²	42.4	61%	0.609	23%	0.234	S	C	*	.	G	3₁₀ helix	trans	-57.7	-25.9	168.6	68.7	-177.6	-180	-174.8	0	112.8	P313 I317 G318 M319	P313-K315 HydrophobicContact CB-CD 4.04Å; P313-K315 HydrophobicContact CB-CG 3.67Å; P313-K315 PolarHBondContact O-N 3.4Å; K315-I317 PolarHBondContact O-N 3Å; K315-G318 PolarHBondContact O-N 3.45Å; K315-M319 WeakPolarHBondContact CA-O 3.44Å
316	L	94.8	Very high	94.9	Very high	35 Å²	35	47.9 Å²	47.9	18%	0.183	25%	0.253	C	S	.	.	G	3₁₀ helix	trans	-61.2	-30.3	178.2	-67	169.5	0	0	0	112.3	D126 Y129 F130 L312 P313 V314	D126-L316 HydrophobicContact CB-CB 4.27Å; D126-L316 HydrophobicContact CB-CD2 3.88Å; Y129-L316 HydrophobicContact CD1-CD1 3.97Å; Y129-L316 HydrophobicContact CE1-CD1 4.31Å; F130-L316 HydrophobicContact CB-CB 4.09Å; F130-L316 HydrophobicContact CB-CD1 4.37Å; F130-L316 HydrophobicContact CD2-CB 4.23Å; F130-L316 HydrophobicContact CD2-CD1 4.25Å; L312-L316 HydrophobicContact CD1-CD1 4.35Å; P313-L316 VanDerWaalsContact O-CB 3.32Å; P313-L316 WeakPolarHBondContact O-CB 3.24Å; P313-L316 WeakPolarHBondContact O-CD1 3.48Å; P313-L316 WeakPolarHBondContact O-CG 3.14Å; P313-L316 PolarHBondContact O-N 3.18Å; V314-L316 PolarHBondContact O-N 3.09Å
317	I	95.9	Very high	95.1	Very high	1 Å²	1	45 Å²	45	1%	0.005	24%	0.239	C	C	.	.	G	3₁₀ helix	trans	-102.6	10.7	175.2	57.9	168.6	0	0	0	112.9	E127 F130 A246 W249 L250 R253 V314 K315 M319	E127-I317 HydrophobicContact CB-CG2 4.41Å; E127-I317 HydrophobicContact CG-CG2 4.28Å; F130-I317 HydrophobicContact CB-CG2 3.77Å; F130-I317 HydrophobicContact CD1-CD1 4.01Å; F130-I317 HydrophobicContact CD1-CG1 4.34Å; F130-I317 HydrophobicContact CD1-CG2 3.51Å; F130-I317 HydrophobicContact CD2-CG2 4.46Å; F130-I317 HydrophobicContact CE1-CD1 3.61Å; F130-I317 HydrophobicContact CE1-CG1 4.3Å; F130-I317 HydrophobicContact CE1-CG2 4.25Å; F130-I317 HydrophobicContact CG-CG2 3.65Å; F130-I317 HydrophobicContact CZ-CD1 3.93Å; F130-I317 HydrophobicContact CZ-CG1 4.47Å; A246-I317 HydrophobicContact CB-CD1 3.68Å; W249-I317 PolarHBondContact NE1-O 3.3Å; L250-I317 HydrophobicContact CD2-CG2 4.47Å; R253-I317 PolarHBondContact NH1-O 3.39Å; V314-I317 WeakPolarHBondContact O-CG1 3.42Å; V314-I317 PolarHBondContact O-N 3.15Å; K315-I317 PolarHBondContact O-N 3Å; I317-M319 HydrophobicContact CD1-CG 4.11Å; I317-M319 HydrophobicContact CD1-SD 3.68Å; I317-M319 HydrophobicContact CG1-CG 4.13Å; I317-M319 HydrophobicContact CG1-SD 4.31Å
318	G	95.3	Very high	95.3	Very high	57 Å²	57	44.8 Å²	44.8	59%	0.588	24%	0.238	S	C	*	.	T	Hydrogen-bonded Turn	trans	80.8	19.2	177.6	0	0	0	0	0	115.5	V314 K315	V314-G318 PolarHBondContact O-N 2.81Å; K315-G318 PolarHBondContact O-N 3.45Å
319	M	97.3	Very high	95.4	Very high	14 Å²	14	46.7 Å²	46.7	7%	0.069	25%	0.247	C	C	.	.			trans	-91.7	158.3	172.4	-64.1	-179.1	77.4	0	0	112.1	A246 W249 V314 K315 I317 M324 F351 F353	A246-M319 HydrophobicContact CB-SD 4.18Å; W249-M319 HydrophobicContact CB-CE 4.08Å; W249-M319 HydrophobicContact CB-CG 4.09Å; W249-M319 HydrophobicContact CB-SD 3.56Å; W249-M319 VanDerWaalsContact CB-SD 3.56Å; W249-M319 VanDerWaalsContact CD1-CG 3.45Å; W249-M319 HydrophobicContact CD2-CG 3.84Å; W249-M319 HydrophobicContact CD2-SD 4.46Å; W249-M319 HydrophobicContact CG-CE 4.42Å; W249-M319 HydrophobicContact CG-CG 3.52Å; W249-M319 HydrophobicContact CG-SD 3.69Å; V314-M319 HydrophobicContact CB-CB 3.93Å; V314-M319 HydrophobicContact CB-SD 4.49Å; V314-M319 HydrophobicContact CG2-CB 3.95Å; V314-M319 PolarHBondContact O-N 3.46Å; V314-M319 VanDerWaalsContact O-N 3.1Å; K315-M319 WeakPolarHBondContact CA-O 3.44Å; I317-M319 HydrophobicContact CD1-CG 4.11Å; I317-M319 HydrophobicContact CD1-SD 3.68Å; I317-M319 HydrophobicContact CG1-CG 4.13Å; I317-M319 HydrophobicContact CG1-SD 4.31Å; M319-M324 HydrophobicContact CE-CE 3.77Å; M319-M324 HydrophobicContact SD-CE 4.23Å; M319-F351 HydrophobicContact CE-CD1 4.45Å; M319-F351 HydrophobicContact CE-CE1 3.78Å; M319-F351 HydrophobicContact CE-CE2 3.99Å; M319-F351 HydrophobicContact CE-CZ 3.52Å; M319-F353 HydrophobicContact CE-CZ 4.07Å
320	N	97.3	Very high	95.7	Very high	77 Å²	77	48.5 Å²	48.5	41%	0.412	25%	0.254	S	S	.	.			trans	-87.2	124.3	176.1	-178.9	-66.5	0	0	0	111	D322 M323 M324	N320-D322 PolarHBondContact O-N 2.92Å; N320-D322 WeakPolarHBondContact OD1-CA 3.33Å; N320-D322 WeakPolarHBondContact OD1-CB 3.44Å; N320-D322 PolarHBondContact OD1-N 3.25Å; N320-M323 HydrophobicContact CB-CB 4.1Å; N320-M323 HydrophobicContact CB-CG 3.91Å; N320-M323 HydrophobicContact CB-SD 3.85Å; N320-M323 PolarHBondContact O-N 3.09Å; N320-M323 PolarHBondContact OD1-N 2.86Å; N320-M324 PolarHBondContact O-N 3.33Å
321	C	96.9	Very high	96.1	Very high	28 Å²	28	43.4 Å²	43.4	19%	0.189	23%	0.227	C	C	.	.	H	α-helix	trans	-62.3	-38.6	-179.1	-66.5	0	0	0	0	113.2	T309 M324 K325	T309-C321 HydrophobicContact CG2-CB 3.73Å; C321-M324 WeakPolarHBondContact O-CB 3.07Å; C321-M324 PolarHBondContact O-N 3.34Å; C321-K325 WeakPolarHBondContact O-CG 3.35Å; C321-K325 PolarHBondContact O-N 2.89Å
322	D	97.4	Very high	96.5	Very high	107 Å²	107	41.4 Å²	41.4	57%	0.572	21%	0.211	S	C	*	.	H	α-helix	trans	-68.3	-37.9	179	-58.2	-42.2	0	0	0	111.3	N320 M324 K325 R326	N320-D322 PolarHBondContact O-N 2.92Å; N320-D322 WeakPolarHBondContact OD1-CA 3.33Å; N320-D322 WeakPolarHBondContact OD1-CB 3.44Å; N320-D322 PolarHBondContact OD1-N 3.25Å; D322-M324 VanDerWaalsContact C-N 3.33Å; D322-K325 PolarHBondContact O-N 2.83Å; D322-R326 WeakPolarHBondContact O-CG 3.37Å; D322-R326 PolarHBondContact O-N 2.77Å
323	M	97.5	Very high	96.8	Very high	73 Å²	73	41.3 Å²	41.3	36%	0.36	21%	0.21	S	C	.	.	H	α-helix	trans	-63.6	-40.6	171.5	-65.8	179.1	71.6	0	0	111.1	N320 K325 R326 Y327 P350 F351	N320-M323 HydrophobicContact CB-CB 4.1Å; N320-M323 HydrophobicContact CB-CG 3.91Å; N320-M323 HydrophobicContact CB-SD 3.85Å; N320-M323 PolarHBondContact O-N 3.09Å; N320-M323 PolarHBondContact OD1-N 2.86Å; M323-K325 PolarHBondContact O-N 3.49Å; M323-R326 PolarHBondContact O-N 3.42Å; M323-Y327 WeakPolarHBondContact O-CB 3.49Å; M323-Y327 PolarHBondContact O-N 3.47Å; M323-P350 HydrophobicContact CB-CB 4.14Å; M323-P350 HydrophobicContact CB-CG 4.29Å; M323-P350 HydrophobicContact CE-CB 3.88Å; M323-P350 WeakPolarHBondContact CE-O 3.37Å; M323-P350 HydrophobicContact CG-CB 4.35Å; M323-P350 WeakPolarHBondContact O-CG 3.47Å; M323-F351 HydrophobicContact CB-CE1 3.7Å; M323-F351 HydrophobicContact CB-CZ 3.99Å; M323-F351 HydrophobicContact CE-CD1 4.05Å; M323-F351 HydrophobicContact CE-CE1 4.02Å
324	M	97.8	Very high	96.9	Very high	0 Å²	0	45.8 Å²	45.8	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-61.8	-43.7	175.2	-176.6	55.6	79.2	0	0	111.8	G242 A245 A246 L308 V314 M319 N320 C321 D322 R326 Y327 I328 F351	G242-M324 VanDerWaalsContact O-CE 3.3Å; G242-M324 WeakPolarHBondContact O-CE 3.34Å; A245-M324 HydrophobicContact CB-CE 4.18Å; A246-M324 HydrophobicContact CB-CE 4.43Å; L308-M324 HydrophobicContact CB-CG 3.96Å; L308-M324 HydrophobicContact CD1-CE 4.32Å; L308-M324 HydrophobicContact CD1-CG 3.93Å; L308-M324 HydrophobicContact CD1-SD 3.89Å; V314-M324 HydrophobicContact CG1-CE 3.86Å; V314-M324 HydrophobicContact CG1-CG 4.2Å; V314-M324 HydrophobicContact CG2-CB 3.93Å; V314-M324 HydrophobicContact CG2-CG 4.35Å; M319-M324 HydrophobicContact CE-CE 3.77Å; M319-M324 HydrophobicContact SD-CE 4.23Å; N320-M324 PolarHBondContact O-N 3.33Å; C321-M324 WeakPolarHBondContact O-CB 3.07Å; C321-M324 PolarHBondContact O-N 3.34Å; D322-M324 VanDerWaalsContact C-N 3.33Å; M324-R326 VanDerWaalsContact C-N 3.35Å; M324-R326 PolarHBondContact O-N 2.59Å; M324-Y327 WeakPolarHBondContact O-CB 3.4Å; M324-Y327 PolarHBondContact O-N 2.96Å; M324-Y327 HydrophobicContact SD-CD1 4.13Å; M324-I328 HydrophobicContact CG-CD1 3.98Å; M324-I328 WeakPolarHBondContact O-CD1 3.28Å; M324-I328 VanDerWaalsContact O-CG1 3.32Å; M324-I328 WeakPolarHBondContact O-CG1 3.43Å; M324-I328 PolarHBondContact O-N 2.98Å; M324-I328 HydrophobicContact SD-CD1 4.33Å; M324-I328 HydrophobicContact SD-CG1 4.32Å; M324-F351 HydrophobicContact CB-CZ 4.44Å; M324-F351 HydrophobicContact CE-CE2 4.15Å; M324-F351 HydrophobicContact CE-CZ 4.33Å; M324-F351 HydrophobicContact SD-CE2 4.15Å
325	K	97.9	Very high	96.9	Very high	64 Å²	64	46 Å²	46	28%	0.278	23%	0.226	S	C	.	.	H	α-helix	trans	-57.3	-46.8	175	-70.3	-173.2	-178.8	-172.2	0	112.2	Q305 T309 C321 D322 M323 Y327 I328 E329	Q305-K325 HydrophobicContact CB-CG 4.18Å; Q305-K325 HydrophobicContact CG-CB 4.23Å; Q305-K325 HydrophobicContact CG-CG 3.93Å; Q305-K325 PolarHBondContact NE2-O 2.83Å; T309-K325 HydrophobicContact CG2-CD 4.16Å; T309-K325 HydrophobicContact CG2-CG 3.72Å; T309-K325 WeakPolarHBondContact OG1-CE 3.43Å; C321-K325 WeakPolarHBondContact O-CG 3.35Å; C321-K325 PolarHBondContact O-N 2.89Å; D322-K325 PolarHBondContact O-N 2.83Å; M323-K325 PolarHBondContact O-N 3.49Å; K325-Y327 VanDerWaalsContact C-N 3.32Å; K325-Y327 PolarHBondContact O-N 2.94Å; K325-I328 PolarHBondContact O-N 3.33Å; K325-E329 WeakPolarHBondContact O-CG 3.49Å; K325-E329 PolarHBondContact O-N 2.99Å; K325-E329 VanDerWaalsContact O-N 3.08Å
326	R	97.7	Very high	97	Very high	144 Å²	144	39.4 Å²	39.4	54%	0.543	20%	0.197	S	C	.	.	H	α-helix	trans	-64	-35.9	177.8	-68.2	178.7	101.7	-175.7	3.9	112.5	D322 M323 M324 E329 F330 P350	D322-R326 WeakPolarHBondContact O-CG 3.37Å; D322-R326 PolarHBondContact O-N 2.77Å; M323-R326 PolarHBondContact O-N 3.42Å; M324-R326 VanDerWaalsContact C-N 3.35Å; M324-R326 PolarHBondContact O-N 2.59Å; R326-E329 PolarHBondContact O-N 3.44Å; R326-F330 WeakPolarHBondContact O-CB 3.45Å; R326-F330 PolarHBondContact O-N 3.15Å; R326-P350 HydrophobicContact CB-CG 4.19Å
327	Y	97.8	Very high	97.1	Very high	16 Å²	16	42 Å²	42	6%	0.063	21%	0.211	C	C	.	.	H	α-helix	trans	-65.3	-45.6	175.6	176.2	-104.8	0	0	0	112	A245 M323 M324 K325 E329 F330 V331 F351 M354	A245-Y327 HydrophobicContact CB-CD1 3.96Å; A245-Y327 HydrophobicContact CB-CE1 3.53Å; M323-Y327 WeakPolarHBondContact O-CB 3.49Å; M323-Y327 PolarHBondContact O-N 3.47Å; M324-Y327 WeakPolarHBondContact O-CB 3.4Å; M324-Y327 PolarHBondContact O-N 2.96Å; M324-Y327 HydrophobicContact SD-CD1 4.13Å; K325-Y327 VanDerWaalsContact C-N 3.32Å; K325-Y327 PolarHBondContact O-N 2.94Å; Y327-E329 VanDerWaalsContact C-N 3.29Å; Y327-E329 PolarHBondContact O-N 3.02Å; Y327-F330 HydrophobicContact CD2-CD1 4.29Å; Y327-F330 HydrophobicContact CE2-CD1 4.33Å; Y327-F330 WeakPolarHBondContact O-CB 3.29Å; Y327-F330 PolarHBondContact O-N 3.07Å; Y327-F330 VanDerWaalsContact O-N 3.15Å; Y327-V331 HydrophobicContact CD1-CG2 4.39Å; Y327-V331 HydrophobicContact CD2-CG2 4.47Å; Y327-V331 HydrophobicContact CE1-CG2 3.87Å; Y327-V331 HydrophobicContact CE2-CG2 3.98Å; Y327-V331 WeakPolarHBondContact O-CG2 3.28Å; Y327-V331 PolarHBondContact O-N 3.36Å; Y327-F351 HydrophobicContact CD1-CD2 4.12Å; Y327-F351 AromaticContact CD1-CE2 3.96Å; Y327-F351 HydrophobicContact CD1-CE2 3.96Å; Y327-F351 AromaticContact CD2-CD2 3.57Å; Y327-F351 HydrophobicContact CD2-CD2 3.57Å; Y327-F351 HydrophobicContact CD2-CE2 4.12Å; Y327-F351 HydrophobicContact CE2-CD2 4.26Å; Y327-F351 AromaticContact CG-CD2 3.49Å; Y327-F351 HydrophobicContact CG-CD2 3.49Å; Y327-F351 VanDerWaalsContact CG-CD2 3.49Å; Y327-F351 AromaticContact CG-CE2 3.54Å; Y327-F351 HydrophobicContact CG-CE2 3.54Å; Y327-M354 HydrophobicContact CE2-CB 4.44Å; Y327-M354 HydrophobicContact CE2-CG 4.02Å; Y327-M354 WeakPolarHBondContact OH-CE 3.18Å
328	I	97.7	Very high	97	Very high	0 Å²	0	44.6 Å²	44.6	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-60	-42.2	176.7	-62.9	156.3	0	0	0	110.5	I238 V301 E304 Q305 L308 M324 K325 V331 A332	I238-I328 HydrophobicContact CG2-CG2 4.13Å; V301-I328 HydrophobicContact CB-CG2 4.38Å; V301-I328 HydrophobicContact CG1-CG2 3.99Å; V301-I328 HydrophobicContact CG2-CG2 4.26Å; E304-I328 HydrophobicContact CB-CD1 4.41Å; E304-I328 HydrophobicContact CB-CG2 3.97Å; E304-I328 HydrophobicContact CG-CB 4.47Å; E304-I328 HydrophobicContact CG-CD1 3.68Å; E304-I328 HydrophobicContact CG-CG1 3.8Å; E304-I328 HydrophobicContact CG-CG2 3.77Å; Q305-I328 HydrophobicContact CB-CD1 4.49Å; Q305-I328 HydrophobicContact CG-CB 4.41Å; Q305-I328 HydrophobicContact CG-CD1 3.86Å; Q305-I328 HydrophobicContact CG-CG2 4.35Å; L308-I328 HydrophobicContact CD1-CD1 4.35Å; M324-I328 HydrophobicContact CG-CD1 3.98Å; M324-I328 WeakPolarHBondContact O-CD1 3.28Å; M324-I328 VanDerWaalsContact O-CG1 3.32Å; M324-I328 WeakPolarHBondContact O-CG1 3.43Å; M324-I328 PolarHBondContact O-N 2.98Å; M324-I328 HydrophobicContact SD-CD1 4.33Å; M324-I328 HydrophobicContact SD-CG1 4.32Å; K325-I328 PolarHBondContact O-N 3.33Å; I328-V331 PolarHBondContact O-N 3.42Å; I328-A332 WeakPolarHBondContact O-CB 3.34Å; I328-A332 PolarHBondContact O-N 3.39Å
329	E	98.3	Very high	97	Very high	41 Å²	41	42.1 Å²	42.1	19%	0.192	20%	0.196	C	C	.	.	H	α-helix	trans	-62.8	-41.6	174.9	-71.3	172.3	178.6	0	0	112.8	V301 Q305 K325 R326 Y327 A332 D333 Y345 S347	V301-E329 HydrophobicContact CG1-CG 4.34Å; Q305-E329 PolarHBondContact NE2-OE1 2.91Å; K325-E329 WeakPolarHBondContact O-CG 3.49Å; K325-E329 PolarHBondContact O-N 2.99Å; K325-E329 VanDerWaalsContact O-N 3.08Å; R326-E329 PolarHBondContact O-N 3.44Å; Y327-E329 VanDerWaalsContact C-N 3.29Å; Y327-E329 PolarHBondContact O-N 3.02Å; E329-A332 PolarHBondContact O-N 3.49Å; E329-D333 WeakPolarHBondContact O-CB 3.43Å; E329-D333 PolarHBondContact O-N 3.15Å; E329-Y345 HydrophobicContact CB-CD1 4.11Å; E329-Y345 HydrophobicContact CB-CD2 4Å; E329-Y345 HydrophobicContact CB-CG 3.68Å; E329-Y345 HydrophobicContact CG-CD1 3.56Å; E329-Y345 HydrophobicContact CG-CD2 4.15Å; E329-Y345 HydrophobicContact CG-CE1 3.95Å; E329-Y345 HydrophobicContact CG-CE2 4.48Å; E329-Y345 HydrophobicContact CG-CG 3.68Å; E329-S347 PolarHBondContact OE2-OG 3.16Å
330	F	97.3	Very high	97	Very high	50 Å²	50	44.7 Å²	44.7	22%	0.219	23%	0.226	C	C	.	.	H	α-helix	trans	-60.3	-44.5	174.8	162.3	-98.8	0	0	0	111.6	R326 Y327 D333 R334 N349	R326-F330 WeakPolarHBondContact O-CB 3.45Å; R326-F330 PolarHBondContact O-N 3.15Å; Y327-F330 HydrophobicContact CD2-CD1 4.29Å; Y327-F330 HydrophobicContact CE2-CD1 4.33Å; Y327-F330 WeakPolarHBondContact O-CB 3.29Å; Y327-F330 PolarHBondContact O-N 3.07Å; Y327-F330 VanDerWaalsContact O-N 3.15Å; F330-D333 PolarHBondContact O-N 2.9Å; F330-R334 PolarHBondContact O-N 3.15Å; F330-N349 HydrophobicContact CD1-CB 3.96Å; F330-N349 HydrophobicContact CD2-CB 4.14Å; F330-N349 HydrophobicContact CE1-CB 3.85Å; F330-N349 HydrophobicContact CE2-CB 4.03Å; F330-N349 HydrophobicContact CG-CB 4.11Å; F330-N349 HydrophobicContact CZ-CB 3.88Å
331	V	96.6	Very high	96.9	Very high	3 Å²	3	42.8 Å²	42.8	2%	0.018	21%	0.214	C	C	.	.	H	α-helix	trans	-63.8	-43.6	176.7	173.5	0	0	0	0	111	G237 Y327 I328 D333 R334 L335	G237-V331 WeakPolarHBondContact O-CG1 3.46Å; Y327-V331 HydrophobicContact CD1-CG2 4.39Å; Y327-V331 HydrophobicContact CD2-CG2 4.47Å; Y327-V331 HydrophobicContact CE1-CG2 3.87Å; Y327-V331 HydrophobicContact CE2-CG2 3.98Å; Y327-V331 WeakPolarHBondContact O-CG2 3.28Å; Y327-V331 PolarHBondContact O-N 3.36Å; I328-V331 PolarHBondContact O-N 3.42Å; V331-D333 PolarHBondContact O-N 2.7Å; V331-R334 WeakPolarHBondContact O-CB 3.28Å; V331-R334 PolarHBondContact O-N 2.9Å; V331-L335 PolarHBondContact O-N 3.32Å
332	A	97.7	Very high	96.9	Very high	0 Å²	0	46.3 Å²	46.3	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-62.5	-40.8	177.6	0	0	0	0	0	112.8	I238 I297 V301 I328 E329 R334 L335 L336 Y345	I238-A332 HydrophobicContact CD1-CB 3.91Å; I297-A332 HydrophobicContact CG2-CB 3.87Å; V301-A332 HydrophobicContact CG2-CB 3.32Å; I328-A332 WeakPolarHBondContact O-CB 3.34Å; I328-A332 PolarHBondContact O-N 3.39Å; E329-A332 PolarHBondContact O-N 3.49Å; A332-R334 VanDerWaalsContact C-N 3.33Å; A332-L335 PolarHBondContact O-N 3.13Å; A332-L336 WeakPolarHBondContact O-CG 2.95Å; A332-L336 PolarHBondContact O-N 2.83Å; A332-Y345 HydrophobicContact CB-CD2 4.37Å; A332-Y345 HydrophobicContact CB-CE2 4.06Å
333	D	97.4	Very high	96.9	Very high	1 Å²	1	45.3 Å²	45.3	1%	0.005	23%	0.23	C	C	.	.	H	α-helix	trans	-64.4	-37.2	174.1	-90.7	-4.4	0	0	0	112.6	E329 F330 V331 L336 L337 K343 V344 Y345 R346	E329-D333 WeakPolarHBondContact O-CB 3.43Å; E329-D333 PolarHBondContact O-N 3.15Å; F330-D333 PolarHBondContact O-N 2.9Å; V331-D333 PolarHBondContact O-N 2.7Å; D333-L336 PolarHBondContact O-N 3.02Å; D333-L337 WeakPolarHBondContact O-CG 3.32Å; D333-L337 PolarHBondContact O-N 3.01Å; D333-L337 VanDerWaalsContact O-N 3.07Å; D333-K343 HydrophobicContact CB-CB 4.32Å; D333-K343 HydrophobicContact CB-CD 4.12Å; D333-K343 HydrophobicContact CB-CG 3.95Å; D333-V344 PolarHBondContact OD1-N 3.38Å; D333-Y345 PolarHBondContact OD1-N 2.77Å; D333-Y345 PolarHBondContact OD2-N 3.38Å; D333-R346 WeakPolarHBondContact OD2-CA 3.34Å; D333-R346 PolarHBondContact OD2-N 2.91Å
334	R	95.2	Very high	96.9	Very high	111 Å²	111	44.3 Å²	44.3	42%	0.419	23%	0.228	S	C	.	.	H	α-helix	trans	-63.3	-46.8	174.4	-169.5	-175	73.2	-160.9	-1.7	110.7	F330 V331 A332 L336 L337 E338	F330-R334 PolarHBondContact O-N 3.15Å; V331-R334 WeakPolarHBondContact O-CB 3.28Å; V331-R334 PolarHBondContact O-N 2.9Å; A332-R334 VanDerWaalsContact C-N 3.33Å; R334-L336 VanDerWaalsContact C-N 3.35Å; R334-L336 PolarHBondContact O-N 3.3Å; R334-L337 WeakPolarHBondContact O-CB 3.47Å; R334-L337 PolarHBondContact O-N 3.48Å; R334-E338 IonicContact NE-OE1 3.44Å; R334-E338 PolarHBondContact O-N 3.18Å
335	L	95.8	Very high	96.8	Very high	4 Å²	4	46.9 Å²	46.9	2%	0.021	24%	0.238	C	C	.	.	H	α-helix	trans	-60.7	-42.9	176.5	178.1	55.3	0	0	0	111.8	A233 I238 C278 I297 V331 A332 L337 E338 L339	A233-L335 HydrophobicContact CB-CD1 4.08Å; A233-L335 HydrophobicContact CB-CD2 4.38Å; I238-L335 HydrophobicContact CD1-CD2 3.93Å; I238-L335 HydrophobicContact CG1-CD2 4.08Å; C278-L335 WeakPolarHBondContact SG-CD1 2.88Å; I297-L335 HydrophobicContact CD1-CD2 3.72Å; I297-L335 HydrophobicContact CD1-CG 4.31Å; V331-L335 PolarHBondContact O-N 3.32Å; A332-L335 PolarHBondContact O-N 3.13Å; L335-L337 VanDerWaalsContact C-N 3.31Å; L335-L337 PolarHBondContact O-N 3.13Å; L335-E338 PolarHBondContact O-N 3.28Å; L335-L339 HydrophobicContact CD1-CD1 4.06Å; L335-L339 HydrophobicContact CD1-CG 4.12Å; L335-L339 HydrophobicContact CG-CD1 4.04Å; L335-L339 WeakPolarHBondContact O-CB 3.47Å; L335-L339 WeakPolarHBondContact O-CG 3.45Å; L335-L339 PolarHBondContact O-N 3.34Å
336	L	97.4	Very high	96.8	Very high	1 Å²	1	53.5 Å²	53.5	1%	0.005	26%	0.261	C	S	.	.	H	α-helix	trans	-58.4	-42.8	175.1	-76.8	167	0	0	0	112	V293 I297 A332 D333 R334 L339 G340 F341 V344	V293-L336 HydrophobicContact CG1-CD2 4.19Å; I297-L336 HydrophobicContact CB-CD2 4.32Å; I297-L336 HydrophobicContact CG1-CD2 3.93Å; I297-L336 HydrophobicContact CG1-CG 4.39Å; I297-L336 HydrophobicContact CG2-CD1 4.24Å; I297-L336 HydrophobicContact CG2-CD2 4.43Å; I297-L336 HydrophobicContact CG2-CG 4.16Å; A332-L336 WeakPolarHBondContact O-CG 2.95Å; A332-L336 PolarHBondContact O-N 2.83Å; D333-L336 PolarHBondContact O-N 3.02Å; R334-L336 VanDerWaalsContact C-N 3.35Å; R334-L336 PolarHBondContact O-N 3.3Å; L336-L339 PolarHBondContact O-N 2.96Å; L336-G340 PolarHBondContact O-N 3.36Å; L336-F341 HydrophobicContact CD2-CB 4.29Å; L336-F341 WeakPolarHBondContact O-CA 3.47Å; L336-F341 PolarHBondContact O-N 2.95Å; L336-V344 HydrophobicContact CD1-CB 4.05Å; L336-V344 HydrophobicContact CD1-CG2 3.6Å
337	L	96.4	Very high	96.6	Very high	91 Å²	91	47.2 Å²	47.2	48%	0.476	24%	0.239	S	C	.	.	H	α-helix	trans	-64.6	-41.7	176	-72.4	173.1	0	0	0	112.4	D333 R334 L335 L339 G340 K343	D333-L337 WeakPolarHBondContact O-CG 3.32Å; D333-L337 PolarHBondContact O-N 3.01Å; D333-L337 VanDerWaalsContact O-N 3.07Å; R334-L337 WeakPolarHBondContact O-CB 3.47Å; R334-L337 PolarHBondContact O-N 3.48Å; L335-L337 VanDerWaalsContact C-N 3.31Å; L335-L337 PolarHBondContact O-N 3.13Å; L337-L339 VanDerWaalsContact C-N 3.29Å; L337-L339 PolarHBondContact O-N 2.7Å; L337-G340 WeakPolarHBondContact O-CA 3.46Å; L337-G340 PolarHBondContact O-N 3.19Å; L337-K343 HydrophobicContact CD1-CD 4.35Å; L337-K343 VanDerWaalsContact CD1-CE 3.42Å; L337-K343 HydrophobicContact CD1-CG 4.03Å; L337-K343 HydrophobicContact CD2-CG 4.22Å; L337-K343 HydrophobicContact CG-CG 4.05Å
338	E	94.1	Very high	96.4	Very high	54 Å²	54	54.1 Å²	54.1	25%	0.252	27%	0.272	S	S	.	.	H	α-helix	trans	-65.4	-33	178.6	-75.5	171.8	-166.2	0	0	112.8	C278 K282 R334 L335 G340	C278-E338 HydrophobicContact CB-CB 4.38Å; K282-E338 WeakPolarHBondContact CE-O 3.21Å; R334-E338 IonicContact NE-OE1 3.44Å; R334-E338 PolarHBondContact O-N 3.18Å; L335-E338 PolarHBondContact O-N 3.28Å; E338-G340 PolarHBondContact O-N 2.97Å
339	L	95.8	Very high	96.3	Very high	6 Å²	6	55.5 Å²	55.5	3%	0.031	28%	0.279	C	S	.	.	T	Hydrogen-bonded Turn	trans	-75.4	-7.4	170.9	-67.9	170.7	0	0	0	113.4	V230 C278 F281 V293 L335 L336 L337 F341	V230-L339 HydrophobicContact CG1-CD1 4.35Å; V230-L339 HydrophobicContact CG2-CD1 4.36Å; C278-L339 HydrophobicContact CB-CD2 4.35Å; F281-L339 HydrophobicContact CB-CD2 3.84Å; F281-L339 HydrophobicContact CD1-CB 4.35Å; F281-L339 HydrophobicContact CD1-CD2 3.72Å; F281-L339 HydrophobicContact CD2-CD2 4.29Å; F281-L339 HydrophobicContact CE1-CB 4.41Å; F281-L339 HydrophobicContact CE1-CD2 4.36Å; F281-L339 WeakPolarHBondContact CE1-O 3.44Å; F281-L339 HydrophobicContact CG-CD2 3.69Å; V293-L339 HydrophobicContact CG1-CD1 4.22Å; L335-L339 HydrophobicContact CD1-CD1 4.06Å; L335-L339 HydrophobicContact CD1-CG 4.12Å; L335-L339 HydrophobicContact CG-CD1 4.04Å; L335-L339 WeakPolarHBondContact O-CB 3.47Å; L335-L339 WeakPolarHBondContact O-CG 3.45Å; L335-L339 PolarHBondContact O-N 3.34Å; L336-L339 PolarHBondContact O-N 2.96Å; L337-L339 VanDerWaalsContact C-N 3.29Å; L337-L339 PolarHBondContact O-N 2.7Å; L339-F341 HydrophobicContact CB-CD2 3.69Å; L339-F341 HydrophobicContact CB-CE2 3.95Å; L339-F341 WeakPolarHBondContact O-CE2 3.43Å
340	G	96	Very high	96.1	Very high	67 Å²	67	55.1 Å²	55.1	69%	0.691	28%	0.28	S	S	*	.	T	Hydrogen-bonded Turn	trans	89.8	18.4	177.6	0	0	0	0	0	115.3	L336 L337 E338	L336-G340 PolarHBondContact O-N 3.36Å; L337-G340 WeakPolarHBondContact O-CA 3.46Å; L337-G340 PolarHBondContact O-N 3.19Å; E338-G340 PolarHBondContact O-N 2.97Å
341	F	96.7	Very high	95.9	Very high	38 Å²	38	53.1 Å²	53.1	17%	0.167	27%	0.272	C	S	.	.			trans	-107	168.3	178.7	-59.7	-80.5	0	0	0	112.2	F281 A290 V293 L336 L339	F281-F341 AromaticContact CE1-CE2 3.65Å; F281-F341 HydrophobicContact CE1-CE2 3.65Å; F281-F341 HydrophobicContact CE1-CZ 4.07Å; F281-F341 AromaticContact CZ-CE2 3.78Å; F281-F341 HydrophobicContact CZ-CE2 3.78Å; F281-F341 AromaticContact CZ-CZ 3.96Å; F281-F341 HydrophobicContact CZ-CZ 3.96Å; A290-F341 HydrophobicContact CB-CD1 3.62Å; A290-F341 HydrophobicContact CB-CE1 3.59Å; V293-F341 HydrophobicContact CB-CD2 4.43Å; V293-F341 HydrophobicContact CB-CE2 4.05Å; V293-F341 HydrophobicContact CB-CZ 4.15Å; V293-F341 HydrophobicContact CG1-CD2 3.79Å; V293-F341 HydrophobicContact CG1-CE2 3.68Å; V293-F341 HydrophobicContact CG1-CG 4.49Å; V293-F341 HydrophobicContact CG1-CZ 4.3Å; V293-F341 HydrophobicContact CG2-CE1 4.46Å; V293-F341 HydrophobicContact CG2-CE2 3.82Å; V293-F341 HydrophobicContact CG2-CZ 3.69Å; L336-F341 HydrophobicContact CD2-CB 4.29Å; L336-F341 WeakPolarHBondContact O-CA 3.47Å; L336-F341 PolarHBondContact O-N 2.95Å; L339-F341 HydrophobicContact CB-CD2 3.69Å; L339-F341 HydrophobicContact CB-CE2 3.95Å; L339-F341 WeakPolarHBondContact O-CE2 3.43Å
342	S	96.9	Very high	95.6	Very high	101 Å²	101	57.2 Å²	57.2	71%	0.706	29%	0.293	S	S	*	.			trans	-82	150.1	177.8	-65.9	0	0	0	0	112
343	K	97.2	Very high	95.1	Very high	87 Å²	87	57.7 Å²	57.7	38%	0.378	30%	0.296	S	S	.	.			trans	-56.2	140.5	171.9	-66.3	-167.2	178.4	-167.2	0	111.8	D333 L337 R346	D333-K343 HydrophobicContact CB-CB 4.32Å; D333-K343 HydrophobicContact CB-CD 4.12Å; D333-K343 HydrophobicContact CB-CG 3.95Å; L337-K343 HydrophobicContact CD1-CD 4.35Å; L337-K343 VanDerWaalsContact CD1-CE 3.42Å; L337-K343 HydrophobicContact CD1-CG 4.03Å; L337-K343 HydrophobicContact CD2-CG 4.22Å; L337-K343 HydrophobicContact CG-CG 4.05Å; K343-R346 HydrophobicContact CB-CG 4.08Å
344	V	96.6	Very high	94.5	Very high	52 Å²	52	58.8 Å²	58.8	32%	0.315	30%	0.301	S	S	.	.	S	Bend	trans	-102	-46	178	170.8	0	0	0	0	110.7	T294 D333 L336	T294-V344 HydrophobicContact CG2-CG2 3.77Å; D333-V344 PolarHBondContact OD1-N 3.38Å; L336-V344 HydrophobicContact CD1-CB 4.05Å; L336-V344 HydrophobicContact CD1-CG2 3.6Å
345	Y	96.6	Very high	93.4	Very high	53 Å²	53	58.8 Å²	58.8	21%	0.208	31%	0.305	C	S	.	.	S	Bend	trans	-90.3	-33.7	-172.5	-59.9	-78.7	0	0	0	112.7	V301 E329 A332 D333 S347	V301-Y345 WeakPolarHBondContact CB-OH 3.49Å; V301-Y345 HydrophobicContact CG1-CE1 4.47Å; V301-Y345 HydrophobicContact CG1-CE2 4.38Å; V301-Y345 WeakPolarHBondContact CG1-OH 3.47Å; V301-Y345 HydrophobicContact CG2-CE2 4.05Å; E329-Y345 HydrophobicContact CB-CD1 4.11Å; E329-Y345 HydrophobicContact CB-CD2 4Å; E329-Y345 HydrophobicContact CB-CG 3.68Å; E329-Y345 HydrophobicContact CG-CD1 3.56Å; E329-Y345 HydrophobicContact CG-CD2 4.15Å; E329-Y345 HydrophobicContact CG-CE1 3.95Å; E329-Y345 HydrophobicContact CG-CE2 4.48Å; E329-Y345 HydrophobicContact CG-CG 3.68Å; A332-Y345 HydrophobicContact CB-CD2 4.37Å; A332-Y345 HydrophobicContact CB-CE2 4.06Å; D333-Y345 PolarHBondContact OD1-N 2.77Å; D333-Y345 PolarHBondContact OD2-N 3.38Å; Y345-S347 PolarHBondContact O-N 2.78Å
346	R	96.5	Very high	91.7	Very high	204 Å²	204	62.7 Å²	62.7	77%	0.77	33%	0.326	S	S	*	.			trans	55.6	34.4	-171.8	-54.7	178.1	-179.9	178.3	-1.2	112.3	D333 K343	D333-R346 WeakPolarHBondContact OD2-CA 3.34Å; D333-R346 PolarHBondContact OD2-N 2.91Å; K343-R346 HydrophobicContact CB-CG 4.08Å
347	S	94.3	Very high	89.9	Confident	12 Å²	12	63.5 Å²	63.5	8%	0.084	33%	0.331	C	S	.	.	P	Polyproline II helix	trans	-80.4	144	179.1	-67	0	0	0	0	110.6	E329 Y345	E329-S347 PolarHBondContact OE2-OG 3.16Å; Y345-S347 PolarHBondContact O-N 2.78Å
348	E	94.5	Very high	87.9	Confident	160 Å²	160	62.4 Å²	62.4	75%	0.748	33%	0.33	S	S	*	.	P	Polyproline II helix	trans	-95.1	155.4	174.2	-65.7	-178.6	167.3	0	0	110	P350	E348-P350 VanDerWaalsContact O-CD 3.25Å; E348-P350 WeakPolarHBondContact O-CD 3.47Å
349	N	94.1	Very high	85.1	Confident	30 Å²	30	65.1 Å²	65.1	16%	0.16	35%	0.346	C	S	.	.	P	Polyproline II helix	trans	-66.5	117.3	176.9	177	22.7	0	0	0	110.4	F330 F351 E355	F330-N349 HydrophobicContact CD1-CB 3.96Å; F330-N349 HydrophobicContact CD2-CB 4.14Å; F330-N349 HydrophobicContact CE1-CB 3.85Å; F330-N349 HydrophobicContact CE2-CB 4.03Å; F330-N349 HydrophobicContact CG-CB 4.11Å; F330-N349 HydrophobicContact CZ-CB 3.88Å; N349-F351 PolarHBondContact ND2-O 3.48Å; N349-F351 PolarHBondContact OD1-N 2.97Å; N349-F351 PolarHBondContact OD1-O 2.76Å; N349-E355 PolarHBondContact ND2-OE1 3.49Å
350	P	94.9	Very high	82.4	Confident	33 Å²	33	69.4 Å²	69.4	21%	0.214	37%	0.366	C	S	.	.			trans	-86.3	-7	179.9	34.2	-31.5	0	0	0	113.3	M323 R326 E348	M323-P350 HydrophobicContact CB-CB 4.14Å; M323-P350 HydrophobicContact CB-CG 4.29Å; M323-P350 HydrophobicContact CE-CB 3.88Å; M323-P350 WeakPolarHBondContact CE-O 3.37Å; M323-P350 HydrophobicContact CG-CB 4.35Å; M323-P350 WeakPolarHBondContact O-CG 3.47Å; R326-P350 HydrophobicContact CB-CG 4.19Å; E348-P350 VanDerWaalsContact O-CD 3.25Å; E348-P350 WeakPolarHBondContact O-CD 3.47Å
351	F	93.9	Very high	79.9	Confident	8 Å²	8	67.6 Å²	67.6	4%	0.035	35%	0.347	C	S	.	.			trans	-111.7	101.2	-173.8	-59.9	-41.5	0	0	0	111.7	A245 M319 M323 M324 Y327 N349 F353 M354	A245-F351 HydrophobicContact CB-CD2 4.34Å; A245-F351 HydrophobicContact CB-CE2 4.36Å; M319-F351 HydrophobicContact CE-CD1 4.45Å; M319-F351 HydrophobicContact CE-CE1 3.78Å; M319-F351 HydrophobicContact CE-CE2 3.99Å; M319-F351 HydrophobicContact CE-CZ 3.52Å; M323-F351 HydrophobicContact CB-CE1 3.7Å; M323-F351 HydrophobicContact CB-CZ 3.99Å; M323-F351 HydrophobicContact CE-CD1 4.05Å; M323-F351 HydrophobicContact CE-CE1 4.02Å; M324-F351 HydrophobicContact CB-CZ 4.44Å; M324-F351 HydrophobicContact CE-CE2 4.15Å; M324-F351 HydrophobicContact CE-CZ 4.33Å; M324-F351 HydrophobicContact SD-CE2 4.15Å; Y327-F351 HydrophobicContact CD1-CD2 4.12Å; Y327-F351 AromaticContact CD1-CE2 3.96Å; Y327-F351 HydrophobicContact CD1-CE2 3.96Å; Y327-F351 AromaticContact CD2-CD2 3.57Å; Y327-F351 HydrophobicContact CD2-CD2 3.57Å; Y327-F351 HydrophobicContact CD2-CE2 4.12Å; Y327-F351 HydrophobicContact CE2-CD2 4.26Å; Y327-F351 AromaticContact CG-CD2 3.49Å; Y327-F351 HydrophobicContact CG-CD2 3.49Å; Y327-F351 VanDerWaalsContact CG-CD2 3.49Å; Y327-F351 AromaticContact CG-CE2 3.54Å; Y327-F351 HydrophobicContact CG-CE2 3.54Å; N349-F351 PolarHBondContact ND2-O 3.48Å; N349-F351 PolarHBondContact OD1-N 2.97Å; N349-F351 PolarHBondContact OD1-O 2.76Å; F351-F353 VanDerWaalsContact C-N 3.25Å; F351-F353 HydrophobicContact CB-CD1 4.08Å; F351-F353 HydrophobicContact CB-CE1 3.63Å; F351-F353 HydrophobicContact CB-CE2 4.21Å; F351-F353 HydrophobicContact CB-CZ 3.7Å; F351-F353 AromaticContact CD1-CE1 3.71Å; F351-F353 HydrophobicContact CD1-CE1 3.71Å; F351-F353 AromaticContact CD1-CZ 3.94Å; F351-F353 HydrophobicContact CD1-CZ 3.94Å; F351-F353 HydrophobicContact CD2-CZ 4.14Å; F351-F353 AromaticContact CG-CE1 3.77Å; F351-F353 HydrophobicContact CG-CE1 3.77Å; F351-F353 HydrophobicContact CG-CE2 4.5Å; F351-F353 AromaticContact CG-CZ 3.67Å; F351-F353 HydrophobicContact CG-CZ 3.67Å; F351-F353 PolarHBondContact O-N 2.76Å; F351-M354 HydrophobicContact CB-CB 4.29Å; F351-M354 HydrophobicContact CB-CG 3.77Å; F351-M354 HydrophobicContact CD2-CG 4.41Å; F351-M354 PolarHBondContact O-N 3.07Å
352	D	89.9	Confident	77.2	Confident	88 Å²	88	72.6 Å²	72.6	47%	0.471	37%	0.369	S	S	.	.	H	α-helix	trans	-53.6	-39.9	174.7	63.4	-22.8	0	0	0	113.1	K252 M354 E355 N356	K252-D352 IonicContact NZ-OD1 2.64Å; K252-D352 PolarHBondContact NZ-OD1 2.96Å; K252-D352 IonicContact NZ-OD2 3.8Å; K252-D352 PolarHBondContact NZ-OD2 3.03Å; D352-M354 VanDerWaalsContact C-N 3.26Å; D352-M354 PolarHBondContact O-N 2.88Å; D352-E355 PolarHBondContact O-N 3.38Å; D352-N356 PolarHBondContact O-N 2.66Å
353	F	87.1	Confident	74.2	Confident	11 Å²	11	71.2 Å²	71.2	5%	0.048	36%	0.356	C	S	.	.	H	α-helix	trans	-67.4	-25.4	-177.5	61.5	-97.2	0	0	0	113.2	F248 W249 K252 M319 F351 E355 N356 I357	F248-F353 HydrophobicContact CB-CD2 3.97Å; F248-F353 HydrophobicContact CB-CE2 3.86Å; W249-F353 HydrophobicContact CB-CZ 4.23Å; W249-F353 HydrophobicContact CE3-CD1 4.4Å; W249-F353 AromaticContact CE3-CE1 3.91Å; W249-F353 HydrophobicContact CE3-CE1 3.91Å; W249-F353 HydrophobicContact CE3-CZ 4.44Å; K252-F353 HydrophobicContact CD-CB 3.95Å; K252-F353 HydrophobicContact CD-CD1 3.85Å; K252-F353 HydrophobicContact CD-CG 4.15Å; M319-F353 HydrophobicContact CE-CZ 4.07Å; F351-F353 VanDerWaalsContact C-N 3.25Å; F351-F353 HydrophobicContact CB-CD1 4.08Å; F351-F353 HydrophobicContact CB-CE1 3.63Å; F351-F353 HydrophobicContact CB-CE2 4.21Å; F351-F353 HydrophobicContact CB-CZ 3.7Å; F351-F353 AromaticContact CD1-CE1 3.71Å; F351-F353 HydrophobicContact CD1-CE1 3.71Å; F351-F353 AromaticContact CD1-CZ 3.94Å; F351-F353 HydrophobicContact CD1-CZ 3.94Å; F351-F353 HydrophobicContact CD2-CZ 4.14Å; F351-F353 AromaticContact CG-CE1 3.77Å; F351-F353 HydrophobicContact CG-CE1 3.77Å; F351-F353 HydrophobicContact CG-CE2 4.5Å; F351-F353 AromaticContact CG-CZ 3.67Å; F351-F353 HydrophobicContact CG-CZ 3.67Å; F351-F353 PolarHBondContact O-N 2.76Å; F353-E355 VanDerWaalsContact C-N 3.28Å; F353-E355 PolarHBondContact O-N 3.34Å; F353-N356 PolarHBondContact O-N 3.18Å; F353-I357 HydrophobicContact CB-CD1 4.4Å; F353-I357 HydrophobicContact CD2-CD1 4.17Å; F353-I357 WeakPolarHBondContact O-CB 3.1Å; F353-I357 VanDerWaalsContact O-CD1 3.27Å; F353-I357 WeakPolarHBondContact O-CD1 3.27Å; F353-I357 WeakPolarHBondContact O-CG1 3.19Å; F353-I357 PolarHBondContact O-N 2.97Å
354	M	83.7	Confident	71.4	Confident	23 Å²	23	71.3 Å²	71.3	11%	0.113	36%	0.361	C	S	.	.	H	α-helix	trans	-69.4	-28.4	176.6	-69.2	-58.9	-54.6	0	0	112.1	A245 F248 Y327 F351 D352 S358	A245-M354 HydrophobicContact CB-SD 4.02Å; F248-M354 HydrophobicContact CB-SD 3.91Å; F248-M354 HydrophobicContact CD2-CE 3.73Å; F248-M354 HydrophobicContact CD2-SD 3.54Å; F248-M354 VanDerWaalsContact CD2-SD 3.54Å; F248-M354 HydrophobicContact CE2-CE 4.06Å; F248-M354 HydrophobicContact CE2-SD 4.42Å; F248-M354 HydrophobicContact CG-SD 4.02Å; Y327-M354 HydrophobicContact CE2-CB 4.44Å; Y327-M354 HydrophobicContact CE2-CG 4.02Å; Y327-M354 WeakPolarHBondContact OH-CE 3.18Å; F351-M354 HydrophobicContact CB-CB 4.29Å; F351-M354 HydrophobicContact CB-CG 3.77Å; F351-M354 HydrophobicContact CD2-CG 4.41Å; F351-M354 PolarHBondContact O-N 3.07Å; D352-M354 VanDerWaalsContact C-N 3.26Å; D352-M354 PolarHBondContact O-N 2.88Å; M354-S358 WeakPolarHBondContact O-CB 3.21Å; M354-S358 PolarHBondContact O-N 3.39Å; M354-S358 PolarHBondContact O-OG 3.01Å
355	E	72.9	Confident	68.6	Low	111 Å²	111	71.1 Å²	71.1	52%	0.519	36%	0.356	S	S	.	.	H	α-helix	trans	-76.6	-44.5	174.6	-71.1	171.9	-162.7	0	0	111.2	N349 D352 F353 I357 S358 L359	N349-E355 PolarHBondContact ND2-OE1 3.49Å; D352-E355 PolarHBondContact O-N 3.38Å; F353-E355 VanDerWaalsContact C-N 3.28Å; F353-E355 PolarHBondContact O-N 3.34Å; E355-I357 PolarHBondContact O-N 2.87Å; E355-S358 PolarHBondContact O-N 2.92Å; E355-L359 WeakPolarHBondContact O-CG 3.47Å; E355-L359 PolarHBondContact O-N 2.7Å
356	N	59.4	Low	65.8	Low	86 Å²	86	74.5 Å²	74.5	46%	0.46	37%	0.372	S	S	.	.	H	α-helix	trans	-64.3	-42.7	-179.4	-65.3	-22.2	0	0	0	112.3	D352 F353 S358 L359 E360	D352-N356 PolarHBondContact O-N 2.66Å; F353-N356 PolarHBondContact O-N 3.18Å; N356-S358 VanDerWaalsContact C-N 3.34Å; N356-S358 PolarHBondContact O-N 3.4Å; N356-L359 WeakPolarHBondContact O-CB 3.32Å; N356-L359 PolarHBondContact O-N 3.35Å; N356-L359 VanDerWaalsContact O-N 3.14Å; N356-E360 PolarHBondContact O-N 2.6Å
357	I	60.2	Low	62.8	Low	19 Å²	19	71.9 Å²	71.9	10%	0.097	37%	0.368	C	S	.	.	H	α-helix	trans	-68.4	-36.5	179.2	-66.5	162.6	0	0	0	111.2	F248 K251 F353 E355 L359 E360 G361	F248-I357 HydrophobicContact CB-CD1 3.73Å; F248-I357 HydrophobicContact CD1-CD1 3.38Å; F248-I357 HydrophobicContact CD1-CG1 4.36Å; F248-I357 HydrophobicContact CD1-CG2 3.87Å; F248-I357 HydrophobicContact CE1-CD1 4.16Å; F248-I357 HydrophobicContact CE1-CG2 3.46Å; F248-I357 VanDerWaalsContact CE1-CG2 3.46Å; F248-I357 HydrophobicContact CG-CD1 3.71Å; F248-I357 HydrophobicContact CZ-CG2 3.91Å; K251-I357 HydrophobicContact CD-CD1 4.47Å; F353-I357 HydrophobicContact CB-CD1 4.4Å; F353-I357 HydrophobicContact CD2-CD1 4.17Å; F353-I357 WeakPolarHBondContact O-CB 3.1Å; F353-I357 VanDerWaalsContact O-CD1 3.27Å; F353-I357 WeakPolarHBondContact O-CD1 3.27Å; F353-I357 WeakPolarHBondContact O-CG1 3.19Å; F353-I357 PolarHBondContact O-N 2.97Å; E355-I357 PolarHBondContact O-N 2.87Å; I357-L359 PolarHBondContact O-N 3.27Å; I357-E360 PolarHBondContact O-N 3.29Å; I357-G361 PolarHBondContact O-N 3.34Å
358	S	54.8	Low	60.2	Low	67 Å²	67	78.9 Å²	78.9	47%	0.469	40%	0.397	S	S	.	.	H	α-helix	trans	-61.7	-27.8	173.6	-64	0	0	0	0	112.7	M354 E355 N356 K362	M354-S358 WeakPolarHBondContact O-CB 3.21Å; M354-S358 PolarHBondContact O-N 3.39Å; M354-S358 PolarHBondContact O-OG 3.01Å; E355-S358 PolarHBondContact O-N 2.92Å; N356-S358 VanDerWaalsContact C-N 3.34Å; N356-S358 PolarHBondContact O-N 3.4Å; S358-K362 WeakPolarHBondContact O-CD 3.11Å; S358-K362 VanDerWaalsContact O-CG 3.24Å; S358-K362 WeakPolarHBondContact O-CG 3.29Å
359	L	35.9	Very low	57.8	Low	112 Å²	112	73.3 Å²	73.3	59%	0.586	37%	0.369	S	S	*	.	H	α-helix	trans	-83.3	-45.1	176.2	-69.7	165.6	0	0	0	111.9	E355 N356 I357 K362 T363	E355-L359 WeakPolarHBondContact O-CG 3.47Å; E355-L359 PolarHBondContact O-N 2.7Å; N356-L359 WeakPolarHBondContact O-CB 3.32Å; N356-L359 PolarHBondContact O-N 3.35Å; N356-L359 VanDerWaalsContact O-N 3.14Å; I357-L359 PolarHBondContact O-N 3.27Å; L359-K362 PolarHBondContact O-N 2.87Å; L359-T363 PolarHBondContact O-N 3.47Å; L359-T363 VanDerWaalsContact O-N 3.1Å; L359-T363 PolarHBondContact O-OG1 3.22Å
360	E	38.2	Very low	55.2	Low	96 Å²	96	74 Å²	74	45%	0.449	38%	0.375	S	S	.	.	H	α-helix	trans	-66.6	-36.5	177.9	-74.6	179.3	179	0	0	113.2	N356 I357 K362 T363 N364	N356-E360 PolarHBondContact O-N 2.6Å; I357-E360 PolarHBondContact O-N 3.29Å; E360-K362 VanDerWaalsContact C-N 3.32Å; E360-T363 PolarHBondContact O-N 2.96Å; E360-T363 PolarHBondContact O-OG1 2.89Å; E360-N364 VanDerWaalsContact O-CB 3.28Å; E360-N364 WeakPolarHBondContact O-CB 3.34Å; E360-N364 PolarHBondContact O-N 3.09Å; E360-N364 PolarHBondContact O-ND2 3.33Å; E360-N364 VanDerWaalsContact O-ND2 3.15Å
361	G	43.3	Very low	52.7	Low	28 Å²	28	75.4 Å²	75.4	29%	0.289	40%	0.395	S	S	.	.	H	α-helix	trans	-67.2	-33.3	174.5	0	0	0	0	0	112.1	I357 F365	I357-G361 PolarHBondContact O-N 3.34Å; G361-F365 WeakPolarHBondContact O-CB 3.31Å; G361-F365 PolarHBondContact O-N 3.32Å
362	K	40.9	Very low	50.2	Low	143 Å²	143	82.4 Å²	82.4	62%	0.622	43%	0.428	S	S	*	.	H	α-helix	trans	-72.2	-36.3	174.6	-76.5	177.3	-175.2	178.5	0	112.7	S358 L359 E360 F366	S358-K362 WeakPolarHBondContact O-CD 3.11Å; S358-K362 VanDerWaalsContact O-CG 3.24Å; S358-K362 WeakPolarHBondContact O-CG 3.29Å; L359-K362 PolarHBondContact O-N 2.87Å; E360-K362 VanDerWaalsContact C-N 3.32Å; K362-F366 VanDerWaalsContact O-CD2 3.31Å; K362-F366 WeakPolarHBondContact O-CD2 3.35Å
363	T	33.7	Very low	47.8	Very low	73 Å²	73	86.6 Å²	86.6	45%	0.448	44%	0.438	S	S	.	.	H	α-helix	trans	-78.6	-50.6	177.5	49.9	0	0	0	0	112	L359 E360 F365 E367	L359-T363 PolarHBondContact O-N 3.47Å; L359-T363 VanDerWaalsContact O-N 3.1Å; L359-T363 PolarHBondContact O-OG1 3.22Å; E360-T363 PolarHBondContact O-N 2.96Å; E360-T363 PolarHBondContact O-OG1 2.89Å; T363-F365 PolarHBondContact O-N 2.66Å; T363-E367 WeakPolarHBondContact O-CB 3.47Å; T363-E367 WeakPolarHBondContact O-CG 3.38Å; T363-E367 PolarHBondContact O-N 3.26Å
364	N	37.2	Very low	45.2	Very low	89 Å²	89	93.5 Å²	93.5	48%	0.476	47%	0.47	S	S	.	.	H	α-helix	trans	-64.8	-36	-176.1	-82.3	-59.8	0	0	0	113.6	E360 K368	E360-N364 VanDerWaalsContact O-CB 3.28Å; E360-N364 WeakPolarHBondContact O-CB 3.34Å; E360-N364 PolarHBondContact O-N 3.09Å; E360-N364 PolarHBondContact O-ND2 3.33Å; E360-N364 VanDerWaalsContact O-ND2 3.15Å; N364-K368 VanDerWaalsContact O-CB 3.28Å; N364-K368 WeakPolarHBondContact O-CB 3.43Å; N364-K368 PolarHBondContact O-N 2.78Å
365	F	39	Very low	43.2	Very low	47 Å²	47	103 Å²	103	21%	0.206	51%	0.505	C	S	.	.	H	α-helix	trans	-77.9	-44.5	-174.2	-170.4	-100.8	0	0	0	112.7	G361 T363 R369	G361-F365 WeakPolarHBondContact O-CB 3.31Å; G361-F365 PolarHBondContact O-N 3.32Å; T363-F365 PolarHBondContact O-N 2.66Å; F365-R369 HydrophobicContact CE2-CG 4.42Å; F365-R369 PolarHBondContact O-N 3.07Å; F365-R369 VanDerWaalsContact O-N 3.15Å
366	F	36.9	Very low	41.6	Very low	124 Å²	124	106.1 Å²	106.1	54%	0.544	52%	0.522	S	S	.	.	H	α-helix	trans	-66.3	-41.1	174	-79.9	-86.4	0	0	0	110.4	K362 V370	K362-F366 VanDerWaalsContact O-CD2 3.31Å; K362-F366 WeakPolarHBondContact O-CD2 3.35Å; F366-V370 HydrophobicContact CB-CG2 4.46Å; F366-V370 HydrophobicContact CD1-CG2 4.31Å; F366-V370 WeakPolarHBondContact O-CB 3.46Å; F366-V370 WeakPolarHBondContact O-CG2 3.49Å; F366-V370 PolarHBondContact O-N 3.14Å
367	E	34.7	Very low	40.9	Very low	149 Å²	149	104.9 Å²	104.9	70%	0.696	53%	0.529	S	S	*	.	H	α-helix	trans	-72.8	-39.9	-177.9	-69.3	178.2	178	0	0	113.5	T363	T363-E367 WeakPolarHBondContact O-CB 3.47Å; T363-E367 WeakPolarHBondContact O-CG 3.38Å; T363-E367 PolarHBondContact O-N 3.26Å
368	K	39.3	Very low	40.3	Very low	159 Å²	159	109.5 Å²	109.5	69%	0.691	56%	0.558	S	S	*	*	H	α-helix	trans	-71.4	-45.6	178.3	-83.6	-175.3	170.5	-179.8	0	113.3	N364	N364-K368 VanDerWaalsContact O-CB 3.28Å; N364-K368 WeakPolarHBondContact O-CB 3.43Å; N364-K368 PolarHBondContact O-N 2.78Å
369	R	42.9	Very low	39.7	Very low	43 Å²	43	113.3 Å²	113.3	16%	0.162	57%	0.57	C	S	.	*	H	α-helix	trans	-82.4	-30.3	-177.4	-80.9	-164.1	-179.9	-175.3	-3.2	114.1	F105 E110 F365 G371 E372 Y373	F105-R369 PolarHBondContact O-NH1 3.31Å; F105-R369 PolarHBondContact O-NH2 3.39Å; E110-R369 IonicContact OE1-NH2 3.21Å; E110-R369 IonicContact OE2-NH2 3.11Å; E110-R369 PolarHBondContact OE2-NH2 3.28Å; E110-R369 VanDerWaalsContact OE2-NH2 3.07Å; F365-R369 HydrophobicContact CE2-CG 4.42Å; F365-R369 PolarHBondContact O-N 3.07Å; F365-R369 VanDerWaalsContact O-N 3.15Å; R369-G371 PolarHBondContact O-N 2.77Å; R369-E372 PolarHBondContact O-N 3.33Å; R369-E372 VanDerWaalsContact O-N 3.09Å; R369-Y373 PolarHBondContact O-N 3.35Å
370	V	40.5	Very low	39.9	Very low	46 Å²	46	111.3 Å²	111.3	28%	0.279	57%	0.565	S	S	.	*	H	α-helix	trans	-64	-29.9	175.2	176.9	0	0	0	0	110.1	F366 E372 Q374	F366-V370 HydrophobicContact CB-CG2 4.46Å; F366-V370 HydrophobicContact CD1-CG2 4.31Å; F366-V370 WeakPolarHBondContact O-CB 3.46Å; F366-V370 WeakPolarHBondContact O-CG2 3.49Å; F366-V370 PolarHBondContact O-N 3.14Å; V370-E372 PolarHBondContact O-N 3.33Å; V370-Q374 HydrophobicContact CG1-CG 3.7Å; V370-Q374 WeakPolarHBondContact O-CB 3.39Å; V370-Q374 VanDerWaalsContact O-CG 3.31Å; V370-Q374 WeakPolarHBondContact O-CG 3.07Å; V370-Q374 PolarHBondContact O-N 3.08Å
371	G	41.6	Very low	40.3	Very low	61 Å²	61	108 Å²	108	63%	0.629	56%	0.558	S	S	*	*	H	α-helix	trans	-63.8	-33.7	171.6	0	0	0	0	0	114.6	R369	R369-G371 PolarHBondContact O-N 2.77Å
372	E	42.8	Very low	40.6	Very low	156 Å²	156	113.4 Å²	113.4	73%	0.729	59%	0.588	S	S	*	*	H	α-helix	trans	-94	-30.5	-176.5	-69.2	-178.6	164.1	0	0	113.3	R369 V370	R369-E372 PolarHBondContact O-N 3.33Å; R369-E372 VanDerWaalsContact O-N 3.09Å; V370-E372 PolarHBondContact O-N 3.33Å
373	Y	39.4	Very low	40.9	Very low	176 Å²	176	111.6 Å²	111.6	69%	0.69	59%	0.589	S	S	*	*	H	α-helix	trans	-101.3	0.6	177.7	-87.3	-90.4	0	0	0	115.2	R369 R375	R369-Y373 PolarHBondContact O-N 3.35Å; Y373-R375 PolarHBondContact O-N 3.13Å
374	Q	32.6	Very low	41.6	Very low	155 Å²	155	113.7 Å²	113.7	72%	0.724	60%	0.597	S	S	*	*			trans	-69	41.5	161.5	-92.5	-172.2	-16.1	0	0	112.6	V370	V370-Q374 HydrophobicContact CG1-CG 3.7Å; V370-Q374 WeakPolarHBondContact O-CB 3.39Å; V370-Q374 VanDerWaalsContact O-CG 3.31Å; V370-Q374 WeakPolarHBondContact O-CG 3.07Å; V370-Q374 PolarHBondContact O-N 3.08Å
375	R	41.2	Very low	41.9	Very low	222 Å²	222	116.2 Å²	116.2	84%	0.838	61%	0.61	S	S	*	*	S	Bend	trans	-111.6	94.8	154.4	-71.3	-169.6	-167.2	178.5	7.1	107.9	Y373	Y373-R375 PolarHBondContact O-N 3.13Å
376	M	39.4	Very low	41.8	Very low	178 Å²	178	118.6 Å²	118.6	88%	0.877	63%	0.629	S	S	*	*	S	Bend	trans	72.3	98.3	159.7	-58.5	-72.7	-74.1	0	0	117.5
377	G	45.5	Very low	42	Very low	59 Å²	59	121.1 Å²	121.1	61%	0.608	64%	0.64	S	S	*	*	S	Bend	trans	100	-4.6	135.7	0	0	0	0	0	119.3
378	V	45.8	Very low	42.5	Very low	116 Å²	116	124.4 Å²	124.4	70%	0.703	65%	0.646	S	S	*	*	S	Bend	trans	-82.4	-19.7	-175.8	-177.5	0	0	0	0	113.3
379	M	42.5	Very low	42.7	Very low	147 Å²	147	123.7 Å²	123.7	72%	0.724	65%	0.649	S	S	*	*	S	Bend	trans	-134.5	9.3	179.6	-65.9	-135.9	-63.6	0	0	115.5
380	S	41.1	Very low	42.8	Very low	70 Å²	70	128.9 Å²	128.9	49%	0.49	68%	0.68	S	S	.	*			trans	-83.6	122.7	-176.5	-48.7	0	0	0	0	111.1
381	G	45.9	Very low	42.6	Very low	28 Å²	28	130.9 Å²	130.9	29%	0.289	70%	0.701	S	S	.	*			trans	-69	157	171	0	0	0	0	0	111.3	T383 D384	G381-T383 PolarHBondContact O-N 3.29Å; G381-D384 PolarHBondContact N-OD2 3.13Å; G381-D384 PolarHBondContact O-N 3.41Å; G381-D384 VanDerWaalsContact O-N 3.13Å
382	P	50	Low	42.5	Very low	141 Å²	141	136.1 Å²	136.1	92%	0.916	72%	0.715	S	S	*	*	T	Hydrogen-bonded Turn	trans	-59	-16.9	-178.9	-21.2	31.3	0	0	0	114.4
383	T	48.2	Very low	42.3	Very low	105 Å²	105	142.1 Å²	142.1	64%	0.644	74%	0.739	S	S	*	*	T	Hydrogen-bonded Turn	trans	-92.1	-13.6	-177.2	49.5	0	0	0	0	114.3	G381 N385 T386	G381-T383 PolarHBondContact O-N 3.29Å; T383-N385 VanDerWaalsContact C-N 3.25Å; T383-N385 PolarHBondContact O-N 3.12Å; T383-T386 PolarHBondContact O-OG1 2.73Å
384	D	47.7	Very low	42.5	Very low	116 Å²	116	140.4 Å²	140.4	62%	0.62	74%	0.741	S	S	*	*	T	Hydrogen-bonded Turn	trans	-78.2	-9.9	-172.9	-72.6	-22	0	0	0	113.6	G381	G381-D384 PolarHBondContact N-OD2 3.13Å; G381-D384 PolarHBondContact O-N 3.41Å; G381-D384 VanDerWaalsContact O-N 3.13Å
385	N	43.8	Very low	43	Very low	142 Å²	142	139.6 Å²	139.6	76%	0.759	74%	0.742	S	S	*	*	T	Hydrogen-bonded Turn	trans	-103.8	33.7	177.9	-72	-18.8	0	0	0	113	T383 F387	T383-N385 VanDerWaalsContact C-N 3.25Å; T383-N385 PolarHBondContact O-N 3.12Å; N385-F387 PolarHBondContact O-N 2.67Å
386	T	37	Very low	43.1	Very low	98 Å²	98	135.1 Å²	135.1	60%	0.601	74%	0.737	S	S	*	*			trans	-90.8	91.3	175.4	-30	0	0	0	0	110.1	T383 R388	T383-T386 PolarHBondContact O-OG1 2.73Å; T386-R388 PolarHBondContact O-N 2.87Å
387	F	40.3	Very low	43.3	Very low	176 Å²	176	132.5 Å²	132.5	77%	0.772	73%	0.729	S	S	*	*			trans	-66.9	115.4	172.8	-156.5	-95.1	0	0	0	109.3	N385 L389	N385-F387 PolarHBondContact O-N 2.67Å; F387-L389 HydrophobicContact CD1-CD1 4.38Å; F387-L389 HydrophobicContact CD1-CG 3.96Å; F387-L389 HydrophobicContact CE1-CD1 4.3Å; F387-L389 HydrophobicContact CE1-CD2 3.84Å; F387-L389 HydrophobicContact CE1-CG 3.75Å
388	R	45.3	Very low	43.2	Very low	219 Å²	219	137.1 Å²	137.1	83%	0.826	74%	0.736	S	S	*	*			trans	-107.3	128.2	171.5	-69.6	-170.4	179.1	-176.7	0.6	109	T386	T386-R388 PolarHBondContact O-N 2.87Å
389	L	44.1	Very low	43	Very low	143 Å²	143	138.5 Å²	138.5	75%	0.749	74%	0.739	S	S	*	*			trans	-96.3	11.8	-176.2	-91.9	163	0	0	0	113.7	F387	F387-L389 HydrophobicContact CD1-CD1 4.38Å; F387-L389 HydrophobicContact CD1-CG 3.96Å; F387-L389 HydrophobicContact CE1-CD1 4.3Å; F387-L389 HydrophobicContact CE1-CD2 3.84Å; F387-L389 HydrophobicContact CE1-CG 3.75Å
390	D	45.4	Very low	43	Very low	153 Å²	153	137.9 Å²	137.9	82%	0.818	74%	0.74	S	S	*	*			trans	-116.5	79.8	-168.6	-41.5	-20.3	0	0	0	108.8
391	A	35.4	Very low	43.2	Very low	87 Å²	87	143.2 Å²	143.2	72%	0.719	76%	0.759	S	S	*	*			trans	-124.2	101.2	164	0	0	0	0	0	107.6
392	D	39	Very low	43	Very low	172 Å²	172	152.8 Å²	152.8	92%	0.92	80%	0.798	S	S	*	*			trans	-67.4	130.9	170.8	-72.6	-37.2	0	0	0	109.2
393	F	39.5	Very low	42.3	Very low	281 Å²	281	153.8 Å²	153.8	100%	1.232	79%	0.787	S	S	*	*			trans	-71	0	-175.2	-95.4	-88.8	0	0	0	114.4

Retrieved 393 of 393 residues in 157.6 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).