A0A3B3VCU2_9TELE Loading...

Fascin

AlphaFold DB , UniProt , Accession A0A3B3VCU2, Species 9TELE (Poecilia latipinna, sailfin molly), Gene n/a, Length 498 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M33.4Very low27Very low239 Ų239125.3 Ų125.3100%1.17781%0.806SS**  01020-77.4-177.5-170.200108.2
2T21.4Very low27.9Very low145 Ų145126.3 Ų126.389%0.8980%0.8SS**  trans-168.8102.6156.421.70000105.5
3T26.9Very low29.2Very low134 Ų134125 Ų12582%0.82278%0.78SS**  trans-66.1127.917242.30000109.9
4N23.4Very low31Very low156 Ų156121.3 Ų121.383%0.83475%0.751SS**  trans-156.278.7159.2-93.2-20.8000109.3
5G23.9Very low33.4Very low84 Ų84121.5 Ų121.587%0.86674%0.74SS**  trans-112.262.5158.100000107.6A7G5-A7 PolarHBondContact O-N 2.58Å
6S22.4Very low36.2Very low84 Ų84114.9 Ų114.959%0.58770%0.699SS**  trans-70.1111167.536.20000107.2N8S6-N8 PolarHBondContact O-N 3.41Å
7A28.2Very low39.2Very low100 Ų100112.7 Ų112.783%0.82668%0.679SS**  trans-62.784.1166.400000108.5G5 G9G5-A7 PolarHBondContact O-N 2.58Å; A7-G9 PolarHBondContact O-N 2.99Å
8N26.8Very low42Very low160 Ų160106.4 Ų106.486%0.85664%0.641SS**  trans-86.790166.6-91.3-0.8000108.2S6S6-N8 PolarHBondContact O-N 3.41Å
9G26Very low44.8Very low57 Ų57100.8 Ų100.859%0.58861%0.608SS**SBendtrans-171.8111.8166.200000104.9A7 S11A7-G9 PolarHBondContact O-N 2.99Å; G9-S11 VanDerWaalsContact C-N 3.26Å; G9-S11 PolarHBondContact O-N 3.34Å
10T29.5Very low47.3Very low134 Ų13495.8 Ų95.882%0.82258%0.577SS**  trans-49.491.6172.842.70000109.5D12T10-D12 PolarHBondContact O-N 3.48Å
11S35Very low49.6Very low85 Ų8591.3 Ų91.359%0.59455%0.55SS**  trans-67.985155.71480000104.1G9 M13G9-S11 VanDerWaalsContact C-N 3.26Å; G9-S11 PolarHBondContact O-N 3.34Å; S11-M13 PolarHBondContact O-N 3.39Å
12D38.2Very low52.6Low138 Ų13880.1 Ų80.174%0.73850%0.495SS*.  trans-52.799.3151.7-86-19.4000104.2T10 L14T10-D12 PolarHBondContact O-N 3.48Å; D12-L14 PolarHBondContact O-N 3.23Å
13M45Very low56Low109 Ų10975.8 Ų75.854%0.53747%0.47SS..  trans-55.4113.9174.2-77.9178101.500105.1S11 Q15 S221S11-M13 PolarHBondContact O-N 3.39Å; M13-Q15 PolarHBondContact O-N 2.98Å; M13-S221 VanDerWaalsContact CE-O 3.27Å; M13-S221 WeakPolarHBondContact CE-O 3.11Å
14L53.5Low59.2Low73 Ų7371.4 Ų71.438%0.38245%0.451SS..  trans-51.2114.2-179.8-102.1124.8000108.1D12 I16 M142D12-L14 PolarHBondContact O-N 3.23Å; L14-I16 PolarHBondContact O-N 3.05Å; L14-I16 VanDerWaalsContact O-N 3.07Å; L14-M142 HydrophobicContact CD2-CB 4.38Å; L14-M142 HydrophobicContact CD2-CE 4.16Å; L14-M142 HydrophobicContact CD2-SD 4.36Å
15Q67.7Low62.4Low125 Ų12568.7 Ų68.758%0.58444%0.437SS*.  trans-60.7114163.4-84.8-170.7-25.800106.5M13 Q17 T51M13-Q15 PolarHBondContact O-N 2.98Å; Q15-Q17 PolarHBondContact O-N 3.18Å; Q15-T51 HydrophobicContact CB-CG2 3.97Å; Q15-T51 HydrophobicContact CG-CG2 4.25Å
16I77.3Confident65.8Low16 Ų1666.9 Ų66.98%0.08241%0.405CS..  trans-72.4105.9-176.7-64.5155.1000107.4L14 F18 T51 L52 M142 F219L14-I16 PolarHBondContact O-N 3.05Å; L14-I16 VanDerWaalsContact O-N 3.07Å; I16-F18 HydrophobicContact CG2-CD1 4.15Å; I16-T51 WeakPolarHBondContact O-CA 3.45Å; I16-L52 PolarHBondContact O-N 3.03Å; I16-M142 HydrophobicContact CG1-CE 4.3Å; I16-M142 HydrophobicContact CG2-CE 4.38Å; I16-F219 HydrophobicContact CD1-CB 4.03Å; I16-F219 HydrophobicContact CD1-CD1 3.36Å; I16-F219 HydrophobicContact CD1-CD2 4.27Å; I16-F219 HydrophobicContact CD1-CE1 3.82Å; I16-F219 HydrophobicContact CD1-CG 3.63Å; I16-F219 HydrophobicContact CD1-CZ 4.46Å; I16-F219 HydrophobicContact CG1-CD1 4.31Å; I16-F219 HydrophobicContact CG1-CE1 4.29Å; I16-F219 HydrophobicContact CG2-CD1 4.45Å; I16-F219 HydrophobicContact CG2-CD2 4.12Å; I16-F219 HydrophobicContact CG2-CE1 4Å; I16-F219 HydrophobicContact CG2-CE2 3.65Å; I16-F219 HydrophobicContact CG2-CZ 3.58Å
17Q87Confident69.3Low77 Ų7763.3 Ų63.336%0.3638%0.379SS..EExtended strand (participates in β ladder)trans-93.3135.2171.1-68-176.3-11.600109.6Q15 I49 W50 A141Q15-Q17 PolarHBondContact O-N 3.18Å; Q17-I49 HydrophobicContact CB-CG2 3.94Å; Q17-I49 HydrophobicContact CG-CG2 4.17Å; Q17-W50 CarbonylContact C-O 3.56Å; Q17-W50 VanDerWaalsContact CA-O 3.29Å; Q17-W50 WeakPolarHBondContact CA-O 3.28Å; Q17-A141 HydrophobicContact CB-CB 3.99Å; Q17-A141 PolarHBondContact O-N 3.39Å
18F91.2Very high72.6Confident0 Ų058.5 Ų58.50%034%0.339CS..EExtended strand (participates in β ladder)trans-156.8160.8-176.962.8-74.8000111.3I16 L20 W50 L52 L66 W105 V138 H139I16-F18 HydrophobicContact CG2-CD1 4.15Å; F18-L20 HydrophobicContact CD2-CD2 4.02Å; F18-L20 HydrophobicContact CD2-CG 4.01Å; F18-L20 HydrophobicContact CE2-CD1 4.06Å; F18-L20 HydrophobicContact CE2-CD2 3.77Å; F18-L20 HydrophobicContact CE2-CG 3.67Å; F18-W50 WeakPolarHBondContact CD1-O 3.36Å; F18-W50 HydrophobicContact CE1-CB 4.27Å; F18-W50 HydrophobicContact CE2-CB 4.37Å; F18-W50 HydrophobicContact CZ-CB 4.11Å; F18-W50 PolarHBondContact N-O 3.2Å; F18-W50 PolarHBondContact O-N 2.76Å; F18-L52 HydrophobicContact CE1-CB 3.63Å; F18-L52 HydrophobicContact CE1-CD1 4.32Å; F18-L52 HydrophobicContact CE1-CG 4.49Å; F18-L52 HydrophobicContact CZ-CB 4.24Å; F18-L52 HydrophobicContact CZ-CD1 4.08Å; F18-L66 HydrophobicContact CE2-CD2 4.41Å; F18-L66 HydrophobicContact CZ-CD2 4.15Å; F18-L66 HydrophobicContact CZ-CG 4.25Å; F18-W105 HydrophobicContact CE2-CZ3 4.17Å; F18-V138 HydrophobicContact CB-CG1 4.02Å; F18-V138 HydrophobicContact CD2-CG1 3.97Å; F18-V138 HydrophobicContact CG-CG1 4.19Å; F18-H139 CarbonylContact C-O 3.49Å; F18-H139 VanDerWaalsContact CA-O 3.23Å; F18-H139 WeakPolarHBondContact CA-O 3.34Å; F18-H139 WeakPolarHBondContact CB-O 3.31Å
19G94Very high76Confident0 Ų051 Ų510%030%0.299CS..EExtended strand (participates in β ladder)trans-104.1154.8163.200000111.1M44 Q48 H139G19-M44 PolarHBondContact N-SD 3.4Å; G19-Q48 WeakPolarHBondContact CA-O 3.46Å; G19-H139 PolarHBondContact N-O 2.83Å; G19-H139 PolarHBondContact O-N 2.87Å
20L95.8Very high79.4Confident0 Ų048.3 Ų48.30%027%0.272CS..EExtended strand (participates in β ladder)trans-112.4124.2173-72.3174.2000109.9F18 Y27 L28 L66 W105 L107 W136 S137 V138F18-L20 HydrophobicContact CD2-CD2 4.02Å; F18-L20 HydrophobicContact CD2-CG 4.01Å; F18-L20 HydrophobicContact CE2-CD1 4.06Å; F18-L20 HydrophobicContact CE2-CD2 3.77Å; F18-L20 HydrophobicContact CE2-CG 3.67Å; L20-Y27 CarbonylContact O-C 3.55Å; L20-Y27 VanDerWaalsContact O-CA 3.26Å; L20-Y27 WeakPolarHBondContact O-CA 3.42Å; L20-L28 HydrophobicContact CB-CB 3.92Å; L20-L28 HydrophobicContact CB-CD2 4.37Å; L20-L28 HydrophobicContact CD1-CD2 3.8Å; L20-L28 PolarHBondContact O-N 3.06Å; L20-L66 HydrophobicContact CD1-CD2 3.63Å; L20-W105 HydrophobicContact CD2-CE3 4.31Å; L20-L107 HydrophobicContact CD1-CD1 4.22Å; L20-L107 HydrophobicContact CD1-CD2 4.29Å; L20-W136 HydrophobicContact CB-CB 4.32Å; L20-W136 HydrophobicContact CB-CD2 4.36Å; L20-W136 HydrophobicContact CB-CE3 3.78Å; L20-W136 HydrophobicContact CB-CZ3 4.49Å; L20-W136 HydrophobicContact CD2-CB 3.92Å; L20-S137 WeakPolarHBondContact CA-O 3.17Å; L20-V138 HydrophobicContact CD2-CG2 3.86Å
21I95.3Very high82.5Confident2 Ų244.5 Ų44.51%0.0124%0.244CC..EExtended strand (participates in β ladder)trans-105.8120.5-177.5-55.7166.8000109.3N25 K26 Y27 W136 S137 H139 F184I21-N25 WeakPolarHBondContact CG2-OD1 3.36Å; I21-K26 CarbonylContact C-O 3.56Å; I21-K26 WeakPolarHBondContact CA-O 3.32Å; I21-Y27 HydrophobicContact CD1-CE1 3.74Å; I21-Y27 HydrophobicContact CG1-CD1 3.71Å; I21-Y27 HydrophobicContact CG1-CE1 3.34Å; I21-Y27 HydrophobicContact CG1-CE2 4.3Å; I21-Y27 HydrophobicContact CG1-CG 4.32Å; I21-W136 CarbonylContact O-C 3.56Å; I21-W136 VanDerWaalsContact O-CA 3.28Å; I21-W136 WeakPolarHBondContact O-CA 3.41Å; I21-S137 PolarHBondContact N-O 2.61Å; I21-S137 PolarHBondContact O-N 3.1Å; I21-H139 HydrophobicContact CD1-CB 3.99Å; I21-F184 HydrophobicContact CD1-CE1 4.1Å; I21-F184 HydrophobicContact CD1-CZ 4.16Å
22N95.3Very high85.2Confident4 Ų443.2 Ų43.22%0.02123%0.233CC..  trans-77.6-177179.176.1-11.6000113G24 N25 K26 A39 G118 W136N22-G24 PolarHBondContact O-N 2.74Å; N22-G24 WeakPolarHBondContact OD1-CA 3.49Å; N22-G24 PolarHBondContact OD1-N 2.69Å; N22-N25 PolarHBondContact O-N 2.82Å; N22-N25 PolarHBondContact OD1-N 3.09Å; N22-K26 PolarHBondContact N-O 3.41Å; N22-K26 WeakPolarHBondContact OD1-CB 3.44Å; N22-K26 PolarHBondContact OD1-N 2.99Å; N22-K26 PolarHBondContact OD1-O 2.85Å; N22-A39 HydrophobicContact CB-CB 4.31Å; N22-A39 WeakPolarHBondContact ND2-CB 3.43Å; N22-G118 PolarHBondContact ND2-O 3.5Å; N22-W136 HydrophobicContact CB-CD2 4.5Å; N22-W136 HydrophobicContact CB-CE3 3.8Å; N22-W136 HydrophobicContact CB-CH2 3.84Å; N22-W136 HydrophobicContact CB-CZ3 3.46Å; N22-W136 VanDerWaalsContact CB-CZ3 3.46Å
23C93.6Very high87.6Confident54 Ų5445.3 Ų45.337%0.36524%0.236SC..THydrogen-bonded Turntrans-61.9-22.7175.662.20000114.9N25 V132C23-N25 VanDerWaalsContact C-N 3.25Å; C23-N25 PolarHBondContact O-N 2.85Å; C23-V132 HydrophobicContact CB-CG1 3.7Å; C23-V132 WeakPolarHBondContact CB-O 3.39Å
24G93.4Very high89.7Confident41 Ų4143 Ų4342%0.42324%0.241SC..THydrogen-bonded Turntrans-84.17.4174.200000114.1N22 K26N22-G24 PolarHBondContact O-N 2.74Å; N22-G24 WeakPolarHBondContact OD1-CA 3.49Å; N22-G24 PolarHBondContact OD1-N 2.69Å; G24-K26 VanDerWaalsContact C-N 3.26Å; G24-K26 PolarHBondContact O-N 3.42Å
25N91.2Very high91.5Very high99 Ų9943.2 Ų43.253%0.52924%0.238SC..SBendtrans57.537.8-174-161.142000113I21 N22 C23 Q187I21-N25 WeakPolarHBondContact CG2-OD1 3.36Å; N22-N25 PolarHBondContact O-N 2.82Å; N22-N25 PolarHBondContact OD1-N 3.09Å; C23-N25 VanDerWaalsContact C-N 3.25Å; C23-N25 PolarHBondContact O-N 2.85Å; N25-Q187 PolarHBondContact OD1-NE2 3.22Å
26K94.6Very high92.7Very high46 Ų4644.6 Ų44.620%0.224%0.242CC..  trans-118.7147177.4-56.4-59.1-165.6136.20111.1I21 N22 G24 A39 S40 A41 T42I21-K26 CarbonylContact C-O 3.56Å; I21-K26 WeakPolarHBondContact CA-O 3.32Å; N22-K26 PolarHBondContact N-O 3.41Å; N22-K26 WeakPolarHBondContact OD1-CB 3.44Å; N22-K26 PolarHBondContact OD1-N 2.99Å; N22-K26 PolarHBondContact OD1-O 2.85Å; G24-K26 VanDerWaalsContact C-N 3.26Å; G24-K26 PolarHBondContact O-N 3.42Å; K26-A39 HydrophobicContact CB-CB 4.37Å; K26-A39 WeakPolarHBondContact CB-O 3.46Å; K26-A39 WeakPolarHBondContact CG-O 3.31Å; K26-S40 WeakPolarHBondContact CD-O 3.36Å; K26-S40 PolarHBondContact NZ-O 3.48Å; K26-A41 CarbonylContact C-O 3.46Å; K26-A41 WeakPolarHBondContact CA-O 3.49Å; K26-T42 HydrophobicContact CD-CG2 3.86Å
27Y96.1Very high93.7Very high9 Ų944.4 Ų44.44%0.03524%0.242CC..EExtended strand (participates in β ladder)trans-83.9133.6-179.1-72.5-88000112.4L20 I21 T29 A39 A41 S43 M44 Q48 H139L20-Y27 CarbonylContact O-C 3.55Å; L20-Y27 VanDerWaalsContact O-CA 3.26Å; L20-Y27 WeakPolarHBondContact O-CA 3.42Å; I21-Y27 HydrophobicContact CD1-CE1 3.74Å; I21-Y27 HydrophobicContact CG1-CD1 3.71Å; I21-Y27 HydrophobicContact CG1-CE1 3.34Å; I21-Y27 HydrophobicContact CG1-CE2 4.3Å; I21-Y27 HydrophobicContact CG1-CG 4.32Å; Y27-T29 PolarHBondContact O-N 2.87Å; Y27-T29 PolarHBondContact O-OG1 3.19Å; Y27-A39 WeakPolarHBondContact O-CA 3.42Å; Y27-A41 PolarHBondContact N-O 3.05Å; Y27-S43 VanDerWaalsContact CD2-C 3.45Å; Y27-M44 HydrophobicContact CD1-CB 4.02Å; Y27-M44 HydrophobicContact CD1-CG 4.35Å; Y27-M44 HydrophobicContact CD2-CB 4.5Å; Y27-M44 HydrophobicContact CE1-CB 3.68Å; Y27-M44 HydrophobicContact CE1-CG 4.2Å; Y27-M44 HydrophobicContact CE1-SD 4.14Å; Y27-M44 HydrophobicContact CE2-CB 4.18Å; Y27-M44 HydrophobicContact CG-CB 4.42Å; Y27-Q48 HydrophobicContact CD1-CB 4.49Å; Y27-Q48 HydrophobicContact CG-CB 4.33Å; Y27-Q48 HydrophobicContact CG-CG 4.15Å; Y27-H139 HydrophobicContact CE1-CB 4.17Å; Y27-H139 AromaticContact CE1-ND1 3.85Å; Y27-H139 AromaticContact CZ-ND1 3.8Å; Y27-H139 PolarHBondContact OH-CE1 2.88Å; Y27-H139 PolarHBondContact OH-ND1 2.89Å
28L97.9Very high94.2Very high0 Ų041.7 Ų41.70%023%0.229CC..EExtended strand (participates in β ladder)trans-55.3125.1165.7-171.271000109.6L20 I37 N38 Q48 W50 I74 I123 W136L20-L28 HydrophobicContact CB-CB 3.92Å; L20-L28 HydrophobicContact CB-CD2 4.37Å; L20-L28 HydrophobicContact CD1-CD2 3.8Å; L20-L28 PolarHBondContact O-N 3.06Å; L28-I37 HydrophobicContact CD1-CG2 3.42Å; L28-I37 VanDerWaalsContact CD1-CG2 3.42Å; L28-I37 HydrophobicContact CG-CG2 4.16Å; L28-N38 CarbonylContact C-O 3.48Å; L28-N38 WeakPolarHBondContact CA-O 3.42Å; L28-Q48 WeakPolarHBondContact O-CA 3.47Å; L28-W50 HydrophobicContact CD2-CD2 4.41Å; L28-W50 HydrophobicContact CD2-CZ2 3.84Å; L28-W50 HydrophobicContact CG-CZ2 3.83Å; L28-W50 PolarHBondContact O-NE1 3.22Å; L28-I74 HydrophobicContact CD2-CD1 4.38Å; L28-I123 HydrophobicContact CD1-CG2 4.45Å; L28-W136 HydrophobicContact CB-CE3 4.47Å; L28-W136 HydrophobicContact CB-CH2 4.44Å; L28-W136 HydrophobicContact CB-CZ3 3.85Å; L28-W136 HydrophobicContact CD1-CH2 3.75Å; L28-W136 HydrophobicContact CD1-CZ2 4.49Å; L28-W136 HydrophobicContact CD1-CZ3 4.04Å; L28-W136 HydrophobicContact CG-CZ3 4.47Å
29T97.6Very high94.4Very high1 Ų141.7 Ų41.71%0.00623%0.229CC..EExtended strand (participates in β ladder)trans-129129.5-168.4-63.10000109.6Y27 I37 N38 A41 K47 Q48Y27-T29 PolarHBondContact O-N 2.87Å; Y27-T29 PolarHBondContact O-OG1 3.19Å; T29-I37 WeakPolarHBondContact O-CA 3.4Å; T29-N38 WeakPolarHBondContact CB-OD1 3.36Å; T29-N38 PolarHBondContact N-O 3.39Å; T29-N38 PolarHBondContact O-N 2.74Å; T29-N38 VanDerWaalsContact O-N 3.09Å; T29-A41 WeakPolarHBondContact OG1-CB 3.37Å; T29-K47 HydrophobicContact CG2-CB 3.91Å; T29-Q48 VanDerWaalsContact CG2-NE2 3.28Å; T29-Q48 PolarHBondContact OG1-NE2 3.14Å
30A97.1Very high94.5Very high2 Ų243.7 Ų43.72%0.01724%0.243CC..EExtended strand (participates in β ladder)trans-92.5117.816600000109.2I37 K47 W50 H69A30-I37 HydrophobicContact CB-CD1 4.02Å; A30-K47 PolarHBondContact N-O 3.12Å; A30-W50 HydrophobicContact CB-CH2 3.82Å; A30-W50 HydrophobicContact CB-CZ2 3.89Å; A30-H69 PolarHBondContact O-CE1 2.93Å
31E95.4Very high94.4Very high53 Ų5344.7 Ų44.725%0.24825%0.251CS..  trans-73.7141176.1-69.3-57.4151.900111.9F33 K36 N38 K47E31-F33 VanDerWaalsContact C-N 3.27Å; E31-F33 PolarHBondContact O-N 2.76Å; E31-K36 PolarHBondContact N-O 3.1Å; E31-N38 WeakPolarHBondContact CG-ND2 3.38Å; E31-N38 PolarHBondContact OE1-ND2 3.31Å; E31-K47 IonicContact OE1-NZ 3.42Å; E31-K47 PolarHBondContact OE1-NZ 2.86Å; E31-K47 IonicContact OE2-NZ 2.69Å; E31-K47 PolarHBondContact OE2-NZ 2.93Å
32T91.5Very high94.1Very high59 Ų5949.4 Ų49.436%0.36228%0.281SS..SBendtrans-66.2-31.6-179.5-51.40000112.2L70T32-L70 HydrophobicContact CG2-CD2 4.5Å
33F89.5Confident93.6Very high182 Ų18250.7 Ų50.780%0.79829%0.29SS*.SBendtrans-117.5139.6-179-57.3-70.7000110.6E31 F35E31-F33 VanDerWaalsContact C-N 3.27Å; E31-F33 PolarHBondContact O-N 2.76Å; F33-F35 PolarHBondContact O-N 3.29Å
34G89.5Confident93.4Very high61 Ų6149 Ų4963%0.62928%0.277SS*.THydrogen-bonded Turntrans723.7178.700000115.1K36G34-K36 PolarHBondContact O-N 3.09Å
35F89.8Confident93.2Very high77 Ų7752.9 Ų52.934%0.33828%0.282SS..THydrogen-bonded Turntrans52.327.3172.8-48.1-58000115.1F33 G84 D85F33-F35 PolarHBondContact O-N 3.29Å; F35-G84 PolarHBondContact O-N 3.36Å; F35-D85 HydrophobicContact CB-CB 3.61Å; F35-D85 HydrophobicContact CD2-CB 3.58Å; F35-D85 HydrophobicContact CE2-CB 4.39Å; F35-D85 HydrophobicContact CG-CB 3.66Å
36K93.7Very high93.1Very high154 Ų15455.4 Ų55.467%0.6729%0.288SS*.BIsolated β-bridgetrans-77.6146.6178.4-67.9-170.2177.3-174.80110.9E31 G34E31-K36 PolarHBondContact N-O 3.1Å; G34-K36 PolarHBondContact O-N 3.09Å
37I97.2Very high93.1Very high12 Ų1256.3 Ų56.36%0.06229%0.292CS..EExtended strand (participates in β ladder)trans-107.4133.5173.6-55.9-51.7000109.3L28 T29 A30 W50 I74 V82 I123L28-I37 HydrophobicContact CD1-CG2 3.42Å; L28-I37 VanDerWaalsContact CD1-CG2 3.42Å; L28-I37 HydrophobicContact CG-CG2 4.16Å; T29-I37 WeakPolarHBondContact O-CA 3.4Å; A30-I37 HydrophobicContact CB-CD1 4.02Å; I37-W50 HydrophobicContact CD1-CH2 3.73Å; I37-W50 HydrophobicContact CD1-CZ2 4.27Å; I37-I74 HydrophobicContact CG1-CG1 4.47Å; I37-I74 HydrophobicContact CG2-CD1 4.36Å; I37-V82 HydrophobicContact CB-CG1 4.13Å; I37-V82 HydrophobicContact CG1-CG1 4.09Å; I37-V82 HydrophobicContact CG2-CG1 4.38Å; I37-I123 HydrophobicContact CG2-CB 4.46Å; I37-I123 HydrophobicContact CG2-CG2 4.09Å
38N97.5Very high93Very high19 Ų1956.4 Ų56.410%0.10229%0.293CS..EExtended strand (participates in β ladder)trans-141.3172.2175.169.471.9000111.2L28 T29 E31 S40 E120L28-N38 CarbonylContact C-O 3.48Å; L28-N38 WeakPolarHBondContact CA-O 3.42Å; T29-N38 WeakPolarHBondContact CB-OD1 3.36Å; T29-N38 PolarHBondContact N-O 3.39Å; T29-N38 PolarHBondContact O-N 2.74Å; T29-N38 VanDerWaalsContact O-N 3.09Å; E31-N38 WeakPolarHBondContact CG-ND2 3.38Å; E31-N38 PolarHBondContact OE1-ND2 3.31Å; N38-S40 PolarHBondContact OD1-N 3.02Å; N38-E120 CarbonylContact C-O 3.48Å; N38-E120 VanDerWaalsContact CA-O 3.32Å; N38-E120 WeakPolarHBondContact CA-O 3.48Å; N38-E120 VanDerWaalsContact CB-O 3.31Å; N38-E120 WeakPolarHBondContact CB-O 3.39Å
39A97.3Very high92.8Very high0 Ų058.3 Ų58.30%030%0.303CS..EExtended strand (participates in β ladder)trans-131.769167.900000110.4N22 K26 Y27 E120 I123 W136N22-A39 HydrophobicContact CB-CB 4.31Å; N22-A39 WeakPolarHBondContact ND2-CB 3.43Å; K26-A39 HydrophobicContact CB-CB 4.37Å; K26-A39 WeakPolarHBondContact CB-O 3.46Å; K26-A39 WeakPolarHBondContact CG-O 3.31Å; Y27-A39 WeakPolarHBondContact O-CA 3.42Å; A39-E120 PolarHBondContact N-O 3.29Å; A39-E120 WeakPolarHBondContact O-CA 3.37Å; A39-E120 PolarHBondContact O-N 2.74Å; A39-I123 HydrophobicContact CB-CD1 3.83Å; A39-I123 HydrophobicContact CB-CG1 4.43Å; A39-W136 HydrophobicContact CB-CH2 4.14Å; A39-W136 HydrophobicContact CB-CZ3 4.18Å
40S94.9Very high92.6Very high42 Ų4258.3 Ų58.329%0.29430%0.303SS..EExtended strand (participates in β ladder)trans-109.8-19.1179.3-65.90000114.4K26 N38 E120K26-S40 WeakPolarHBondContact CD-O 3.36Å; K26-S40 PolarHBondContact NZ-O 3.48Å; N38-S40 PolarHBondContact OD1-N 3.02Å; S40-E120 VanDerWaalsContact CA-OE2 3.28Å; S40-E120 WeakPolarHBondContact CA-OE2 3.49Å; S40-E120 WeakPolarHBondContact CB-OE2 3.42Å; S40-E120 WeakPolarHBondContact OG-CA 3.45Å; S40-E120 PolarHBondContact OG-OE2 3.5Å
41A93.1Very high92.4Very high21 Ų2158.9 Ų58.917%0.17431%0.306CS..EExtended strand (participates in β ladder)trans-74.4132.5-173.200000112.3K26 Y27 T29 Q48K26-A41 CarbonylContact C-O 3.46Å; K26-A41 WeakPolarHBondContact CA-O 3.49Å; Y27-A41 PolarHBondContact N-O 3.05Å; T29-A41 WeakPolarHBondContact OG1-CB 3.37Å; A41-Q48 HydrophobicContact CB-CG 3.86Å
42T89.1Confident92Very high102 Ų10257.3 Ų57.363%0.62630%0.299SS*.SBendtrans-87.4-10.2178.151.30000114K26K26-T42 HydrophobicContact CD-CG2 3.86Å
43S85.4Confident91.8Very high30 Ų3056.6 Ų56.621%0.2129%0.292CS..SBendtrans-137.8143.6-177.263.60000110.2Y27 K45Y27-S43 VanDerWaalsContact CD2-C 3.45Å; S43-K45 PolarHBondContact O-N 3.27Å
44M90.2Very high91.3Very high20 Ų2050.4 Ų50.410%0.09927%0.266CS..  trans-75112.8170.8-168.1168.366.900110.8G19 Y27 Q48 I49 A141 S412G19-M44 PolarHBondContact N-SD 3.4Å; Y27-M44 HydrophobicContact CD1-CB 4.02Å; Y27-M44 HydrophobicContact CD1-CG 4.35Å; Y27-M44 HydrophobicContact CD2-CB 4.5Å; Y27-M44 HydrophobicContact CE1-CB 3.68Å; Y27-M44 HydrophobicContact CE1-CG 4.2Å; Y27-M44 HydrophobicContact CE1-SD 4.14Å; Y27-M44 HydrophobicContact CE2-CB 4.18Å; Y27-M44 HydrophobicContact CG-CB 4.42Å; M44-Q48 HydrophobicContact CB-CB 4.44Å; M44-Q48 HydrophobicContact CG-CB 4.02Å; M44-I49 HydrophobicContact CG-CG1 4.3Å; M44-A141 HydrophobicContact CE-CB 3.76Å; M44-A141 HydrophobicContact SD-CB 4.1Å; M44-S412 VanDerWaalsContact N-CB 3.32Å
45K87.9Confident90.4Very high121 Ų12148.2 Ų48.253%0.52624%0.24SC..  trans-124.3-169.3167.8-58.2-175.3177.9-174.90108.9S43 K47 Q48 I49S43-K45 PolarHBondContact O-N 3.27Å; K45-K47 VanDerWaalsContact C-N 3.27Å; K45-K47 PolarHBondContact O-N 3.47Å; K45-K47 VanDerWaalsContact O-N 3.12Å; K45-Q48 WeakPolarHBondContact O-CB 3.49Å; K45-Q48 PolarHBondContact O-N 3.43Å; K45-Q48 PolarHBondContact O-OE1 2.83Å; K45-I49 PolarHBondContact O-N 3.37Å
46K89.2Confident89Confident152 Ų15248.2 Ų48.266%0.66126%0.262SS*.G310 helixtrans-45.7-46.1179.9-170.6179.6-175.7-178.70113.7Q48 I49 H69K46-Q48 PolarHBondContact O-N 2.89Å; K46-I49 PolarHBondContact O-N 3.17Å; K46-H69 HydrophobicContact CG-CB 4.07Å; K46-H69 VanDerWaalsContact O-CB 3.27Å; K46-H69 WeakPolarHBondContact O-CB 3.46Å
47K94.6Very high87.1Confident66 Ų6648.2 Ų48.229%0.28727%0.269SS..G310 helixtrans-69.9-16.3-177-60.4-163.7-59.91740114.6T29 A30 E31 K45T29-K47 HydrophobicContact CG2-CB 3.91Å; A30-K47 PolarHBondContact N-O 3.12Å; E31-K47 IonicContact OE1-NZ 3.42Å; E31-K47 PolarHBondContact OE1-NZ 2.86Å; E31-K47 IonicContact OE2-NZ 2.69Å; E31-K47 PolarHBondContact OE2-NZ 2.93Å; K45-K47 VanDerWaalsContact C-N 3.27Å; K45-K47 PolarHBondContact O-N 3.47Å; K45-K47 VanDerWaalsContact O-N 3.12Å
48Q95.3Very high85Confident10 Ų1051.5 Ų51.55%0.04729%0.287CS..G310 helixtrans-99.4-3.6-178.2-67.668.643.800112.6G19 Y27 L28 T29 A41 M44 K45 K46G19-Q48 WeakPolarHBondContact CA-O 3.46Å; Y27-Q48 HydrophobicContact CD1-CB 4.49Å; Y27-Q48 HydrophobicContact CG-CB 4.33Å; Y27-Q48 HydrophobicContact CG-CG 4.15Å; L28-Q48 WeakPolarHBondContact O-CA 3.47Å; T29-Q48 VanDerWaalsContact CG2-NE2 3.28Å; T29-Q48 PolarHBondContact OG1-NE2 3.14Å; A41-Q48 HydrophobicContact CB-CG 3.86Å; M44-Q48 HydrophobicContact CB-CB 4.44Å; M44-Q48 HydrophobicContact CG-CB 4.02Å; K45-Q48 WeakPolarHBondContact O-CB 3.49Å; K45-Q48 PolarHBondContact O-N 3.43Å; K45-Q48 PolarHBondContact O-OE1 2.83Å; K46-Q48 PolarHBondContact O-N 2.89Å
49I93.1Very high82.8Confident41 Ų4155.5 Ų55.521%0.2132%0.316CS..  trans-86.2127178.9-65.7171.6000109.4Q17 M44 K45 K46 H69 A141Q17-I49 HydrophobicContact CB-CG2 3.94Å; Q17-I49 HydrophobicContact CG-CG2 4.17Å; M44-I49 HydrophobicContact CG-CG1 4.3Å; K45-I49 PolarHBondContact O-N 3.37Å; K46-I49 PolarHBondContact O-N 3.17Å; I49-H69 PolarHBondContact O-N 2.79Å; I49-A141 HydrophobicContact CD1-CB 4.43Å; I49-A141 HydrophobicContact CG1-CB 4.24Å
50W93.9Very high80.5Confident0 Ų060.1 Ų60.10%035%0.349CS..EExtended strand (participates in β ladder)trans-120.1146.5175.2-61.188.6000109.7Q17 F18 L28 A30 I37 L66 K67 I74Q17-W50 CarbonylContact C-O 3.56Å; Q17-W50 VanDerWaalsContact CA-O 3.29Å; Q17-W50 WeakPolarHBondContact CA-O 3.28Å; F18-W50 WeakPolarHBondContact CD1-O 3.36Å; F18-W50 HydrophobicContact CE1-CB 4.27Å; F18-W50 HydrophobicContact CE2-CB 4.37Å; F18-W50 HydrophobicContact CZ-CB 4.11Å; F18-W50 PolarHBondContact N-O 3.2Å; F18-W50 PolarHBondContact O-N 2.76Å; L28-W50 HydrophobicContact CD2-CD2 4.41Å; L28-W50 HydrophobicContact CD2-CZ2 3.84Å; L28-W50 HydrophobicContact CG-CZ2 3.83Å; L28-W50 PolarHBondContact O-NE1 3.22Å; A30-W50 HydrophobicContact CB-CH2 3.82Å; A30-W50 HydrophobicContact CB-CZ2 3.89Å; I37-W50 HydrophobicContact CD1-CH2 3.73Å; I37-W50 HydrophobicContact CD1-CZ2 4.27Å; W50-L66 HydrophobicContact CE3-CB 4.14Å; W50-K67 CarbonylContact C-O 3.56Å; W50-K67 VanDerWaalsContact CA-O 3.32Å; W50-K67 WeakPolarHBondContact CA-O 3.24Å; W50-I74 HydrophobicContact CH2-CB 4.49Å; W50-I74 HydrophobicContact CZ3-CB 4.17Å
51T91.5Very high78.9Confident15 Ų1559.5 Ų59.59%0.09235%0.346CS..EExtended strand (participates in β ladder)trans-110134.1173.6-53.90000109.2Q15 I16 E53 K67Q15-T51 HydrophobicContact CB-CG2 3.97Å; Q15-T51 HydrophobicContact CG-CG2 4.25Å; I16-T51 WeakPolarHBondContact O-CA 3.45Å; T51-E53 HydrophobicContact CG2-CG 4.44Å; T51-K67 PolarHBondContact N-O 3.19Å; T51-K67 PolarHBondContact O-N 2.87Å
52L88.2Confident78.1Confident20 Ų2060 Ų6011%0.10535%0.346CS..EExtended strand (participates in β ladder)trans-91.8116.9177.5-161.366.8000109.4I16 F18 F64 L66 I97 F219I16-L52 PolarHBondContact O-N 3.03Å; F18-L52 HydrophobicContact CE1-CB 3.63Å; F18-L52 HydrophobicContact CE1-CD1 4.32Å; F18-L52 HydrophobicContact CE1-CG 4.49Å; F18-L52 HydrophobicContact CZ-CB 4.24Å; F18-L52 HydrophobicContact CZ-CD1 4.08Å; L52-F64 HydrophobicContact CD1-CB 3.53Å; L52-F64 HydrophobicContact CD1-CD1 4.01Å; L52-F64 HydrophobicContact CD1-CG 3.81Å; L52-F64 HydrophobicContact CD2-CD1 3.72Å; L52-F64 HydrophobicContact CD2-CE1 3.92Å; L52-F64 HydrophobicContact CD2-CG 4.15Å; L52-F64 HydrophobicContact CD2-CZ 4.49Å; L52-F64 HydrophobicContact CG-CB 4.07Å; L52-F64 HydrophobicContact CG-CD1 3.61Å; L52-F64 HydrophobicContact CG-CE1 4.28Å; L52-F64 HydrophobicContact CG-CG 3.96Å; L52-L66 HydrophobicContact CD1-CD1 4.04Å; L52-L66 HydrophobicContact CD1-CG 4.23Å; L52-I97 HydrophobicContact CD1-CD1 3.64Å; L52-I97 HydrophobicContact CD2-CD1 4.35Å; L52-F219 HydrophobicContact CD2-CB 3.89Å; L52-F219 HydrophobicContact CD2-CD2 3.94Å; L52-F219 HydrophobicContact CD2-CG 4.33Å
53E87.3Confident78Confident44 Ų4455.4 Ų55.421%0.20632%0.318CS..EExtended strand (participates in β ladder)trans-113127.5175.2-63.5-176.1-177.200109T51 F64 F65 K67 Y73T51-E53 HydrophobicContact CG2-CG 4.44Å; E53-F64 CarbonylContact O-C 3.58Å; E53-F64 VanDerWaalsContact O-CA 3.32Å; E53-F64 WeakPolarHBondContact O-CA 3.4Å; E53-F65 HydrophobicContact CB-CB 4.35Å; E53-F65 PolarHBondContact N-O 2.93Å; E53-F65 PolarHBondContact O-N 3.01Å; E53-K67 WeakPolarHBondContact OE1-CD 3.16Å; E53-K67 IonicContact OE1-NZ 3.94Å; E53-K67 PolarHBondContact OE1-NZ 2.91Å; E53-K67 IonicContact OE2-NZ 3.86Å; E53-Y73 WeakPolarHBondContact OE2-CE1 3.37Å; E53-Y73 PolarHBondContact OE2-OH 3.1Å
54Q79.1Confident78.2Confident52 Ų5254.3 Ų54.324%0.24331%0.309CS..EExtended strand (participates in β ladder)trans-87.6142.7177.9-165.91778.300110.4G56 F64 S221Q54-G56 PolarHBondContact O-N 2.56Å; Q54-F64 HydrophobicContact CB-CD1 3.95Å; Q54-F64 HydrophobicContact CB-CE1 3.97Å; Q54-F64 HydrophobicContact CG-CD1 4.07Å; Q54-F64 HydrophobicContact CG-CE1 3.86Å; Q54-S221 PolarHBondContact OE1-OG 2.94Å
55S70.1Confident78.3Confident14 Ų1454 Ų5410%0.09831%0.308CS..  trans-63.7127.2171-172.10000110.6D57 V63 R94S55-D57 VanDerWaalsContact C-N 3.27Å; S55-D57 PolarHBondContact O-N 3.1Å; S55-V63 PolarHBondContact N-O 3.32Å; S55-R94 PolarHBondContact OG-NH1 3.48Å
56G59.5Low78.6Confident77 Ų7748.3 Ų48.379%0.79428%0.283SS*.THydrogen-bonded Turntrans-72.1-15.6-176.400000115.1Q54Q54-G56 PolarHBondContact O-N 2.56Å
57D55.1Low78.9Confident154 Ų15443.5 Ų43.582%0.82426%0.262SS*.THydrogen-bonded Turntrans-87.3-12.9-168.3-70-26.3000114.3S55S55-D57 VanDerWaalsContact C-N 3.27Å; S55-D57 PolarHBondContact O-N 3.1Å
58D52Low78.9Confident82 Ų8240.6 Ų40.644%0.43925%0.25SC..  trans-154.895175.5-160.8-10.4000112.6S60 A61D58-S60 VanDerWaalsContact CG-OG 3.23Å; D58-S60 PolarHBondContact O-N 3.44Å; D58-S60 WeakPolarHBondContact OD1-CB 3.31Å; D58-S60 PolarHBondContact OD1-N 2.91Å; D58-S60 VanDerWaalsContact OD1-N 3.09Å; D58-S60 PolarHBondContact OD1-OG 3.36Å; D58-S60 PolarHBondContact OD2-OG 2.9Å; D58-A61 HydrophobicContact CB-CB 4.05Å; D58-A61 PolarHBondContact O-N 3.26Å
59S51.3Low78.8Confident102 Ų10242.3 Ų42.371%0.71326%0.258SS*.THydrogen-bonded Turntrans-59.1-10.9174.862.70000114.3
60S50.8Low78.8Confident97 Ų9743.2 Ų43.268%0.67826%0.263SS*.THydrogen-bonded Turntrans-89.4-21.7175.579.20000113.7D58D58-S60 VanDerWaalsContact CG-OG 3.23Å; D58-S60 PolarHBondContact O-N 3.44Å; D58-S60 WeakPolarHBondContact OD1-CB 3.31Å; D58-S60 PolarHBondContact OD1-N 2.91Å; D58-S60 VanDerWaalsContact OD1-N 3.09Å; D58-S60 PolarHBondContact OD1-OG 3.36Å; D58-S60 PolarHBondContact OD2-OG 2.9Å
61A60.1Low78.8Confident29 Ų2944.9 Ų44.924%0.2428%0.28CS..SBendtrans-87.8123.7178.900000110D58 V63D58-A61 HydrophobicContact CB-CB 4.05Å; D58-A61 PolarHBondContact O-N 3.26Å; A61-V63 HydrophobicContact CB-CB 4.44Å; A61-V63 HydrophobicContact CB-CG2 3.79Å; A61-V63 PolarHBondContact O-N 2.79Å
62N76.6Confident79Confident33 Ų3346.6 Ų46.618%0.17629%0.285CS..  trans-76.548.6178.8-153.134.9000111.6F64 V96 I97N62-F64 HydrophobicContact CB-CE2 4.37Å; N62-F64 WeakPolarHBondContact O-CD2 3.33Å; N62-F64 WeakPolarHBondContact O-CE2 3.19Å; N62-F64 WeakPolarHBondContact OD1-CE2 3.34Å; N62-F64 VanDerWaalsContact OD1-CZ 3.29Å; N62-F64 WeakPolarHBondContact OD1-CZ 3.02Å; N62-V96 WeakPolarHBondContact O-CA 3.22Å; N62-I97 PolarHBondContact ND2-O 3.39Å; N62-I97 PolarHBondContact O-N 2.86Å
63V87.8Confident79.4Confident5 Ų546.6 Ų46.63%0.0328%0.283CS..EExtended strand (participates in β ladder)trans-106.7125.4-170.5-179.90000109.6S55 A61 R94 F95 V96 E110S55-V63 PolarHBondContact N-O 3.32Å; A61-V63 HydrophobicContact CB-CB 4.44Å; A61-V63 HydrophobicContact CB-CG2 3.79Å; A61-V63 PolarHBondContact O-N 2.79Å; V63-R94 HydrophobicContact CG1-CB 3.84Å; V63-R94 HydrophobicContact CG1-CG 4.23Å; V63-F95 WeakPolarHBondContact CA-O 3.42Å; V63-V96 HydrophobicContact CG2-CG2 4.01Å; V63-E110 HydrophobicContact CG2-CG 4.35Å; V63-E110 WeakPolarHBondContact CG2-OE1 3.41Å
64F89.4Confident79.8Confident6 Ų644.5 Ų44.53%0.02627%0.274CS..EExtended strand (participates in β ladder)trans-131.6157.7-174.9-55.9-86.5000112L52 E53 Q54 N62 F95 I97 F219L52-F64 HydrophobicContact CD1-CB 3.53Å; L52-F64 HydrophobicContact CD1-CD1 4.01Å; L52-F64 HydrophobicContact CD1-CG 3.81Å; L52-F64 HydrophobicContact CD2-CD1 3.72Å; L52-F64 HydrophobicContact CD2-CE1 3.92Å; L52-F64 HydrophobicContact CD2-CG 4.15Å; L52-F64 HydrophobicContact CD2-CZ 4.49Å; L52-F64 HydrophobicContact CG-CB 4.07Å; L52-F64 HydrophobicContact CG-CD1 3.61Å; L52-F64 HydrophobicContact CG-CE1 4.28Å; L52-F64 HydrophobicContact CG-CG 3.96Å; E53-F64 CarbonylContact O-C 3.58Å; E53-F64 VanDerWaalsContact O-CA 3.32Å; E53-F64 WeakPolarHBondContact O-CA 3.4Å; Q54-F64 HydrophobicContact CB-CD1 3.95Å; Q54-F64 HydrophobicContact CB-CE1 3.97Å; Q54-F64 HydrophobicContact CG-CD1 4.07Å; Q54-F64 HydrophobicContact CG-CE1 3.86Å; N62-F64 HydrophobicContact CB-CE2 4.37Å; N62-F64 WeakPolarHBondContact O-CD2 3.33Å; N62-F64 WeakPolarHBondContact O-CE2 3.19Å; N62-F64 WeakPolarHBondContact OD1-CE2 3.34Å; N62-F64 VanDerWaalsContact OD1-CZ 3.29Å; N62-F64 WeakPolarHBondContact OD1-CZ 3.02Å; F64-F95 PolarHBondContact N-O 2.81Å; F64-F95 PolarHBondContact O-N 2.75Å; F64-I97 HydrophobicContact CB-CD1 4.21Å; F64-I97 HydrophobicContact CD2-CB 4.1Å; F64-I97 HydrophobicContact CD2-CD1 3.63Å; F64-I97 HydrophobicContact CD2-CG1 3.82Å; F64-I97 HydrophobicContact CE2-CB 4.22Å; F64-I97 HydrophobicContact CE2-CD1 4.24Å; F64-I97 HydrophobicContact CE2-CG1 4.42Å; F64-I97 HydrophobicContact CG-CD1 4.07Å; F64-F219 VanDerWaalsContact CZ-O 3.26Å; F64-F219 WeakPolarHBondContact CZ-O 3.49Å
65F92.1Very high80.6Confident15 Ų1542.2 Ų42.27%0.06626%0.264CS..EExtended strand (participates in β ladder)trans-107.3139.6165.4-53.5-85.8000108.3E53 Y73 A89 C93 R94E53-F65 HydrophobicContact CB-CB 4.35Å; E53-F65 PolarHBondContact N-O 2.93Å; E53-F65 PolarHBondContact O-N 3.01Å; F65-Y73 HydrophobicContact CB-CD1 3.66Å; F65-Y73 HydrophobicContact CB-CE1 3.86Å; F65-Y73 HydrophobicContact CG-CD1 4.46Å; F65-A89 HydrophobicContact CD1-CB 3.92Å; F65-A89 HydrophobicContact CD2-CB 4.46Å; F65-A89 HydrophobicContact CE1-CB 3.69Å; F65-A89 HydrophobicContact CE2-CB 4.25Å; F65-A89 HydrophobicContact CG-CB 4.3Å; F65-A89 HydrophobicContact CZ-CB 3.87Å; F65-C93 HydrophobicContact CD1-CB 3.7Å; F65-C93 VanDerWaalsContact CD1-O 3.28Å; F65-C93 WeakPolarHBondContact CD1-O 3.44Å; F65-C93 HydrophobicContact CE1-CB 4.09Å; F65-R94 HydrophobicContact CD1-CG 4.37Å; F65-R94 HydrophobicContact CE1-CB 4.5Å; F65-R94 HydrophobicContact CE1-CG 3.44Å; F65-R94 VanDerWaalsContact CE1-CG 3.44Å; F65-R94 HydrophobicContact CZ-CG 3.7Å
66L94.3Very high81.9Confident0 Ų041.6 Ų41.60%026%0.259CS..EExtended strand (participates in β ladder)trans-107.9116.4172.9-75.375000108.5F18 L20 W50 L52 Y73 I74 F95 L107F18-L66 HydrophobicContact CE2-CD2 4.41Å; F18-L66 HydrophobicContact CZ-CD2 4.15Å; F18-L66 HydrophobicContact CZ-CG 4.25Å; L20-L66 HydrophobicContact CD1-CD2 3.63Å; W50-L66 HydrophobicContact CE3-CB 4.14Å; L52-L66 HydrophobicContact CD1-CD1 4.04Å; L52-L66 HydrophobicContact CD1-CG 4.23Å; L66-Y73 WeakPolarHBondContact O-CA 3.49Å; L66-I74 HydrophobicContact CB-CG2 3.66Å; L66-I74 PolarHBondContact O-N 2.99Å; L66-F95 HydrophobicContact CD1-CB 4.49Å; L66-L107 HydrophobicContact CD1-CD2 3.73Å; L66-L107 HydrophobicContact CD2-CD2 3.54Å; L66-L107 HydrophobicContact CG-CD2 4.31Å
67K94.7Very high83.7Confident51 Ų5140 Ų4022%0.22223%0.232CC..EExtended strand (participates in β ladder)trans-107127.1-176.9-168.8175.4-171.5162.30111W50 T51 E53 G71 R72 Y73W50-K67 CarbonylContact C-O 3.56Å; W50-K67 VanDerWaalsContact CA-O 3.32Å; W50-K67 WeakPolarHBondContact CA-O 3.24Å; T51-K67 PolarHBondContact N-O 3.19Å; T51-K67 PolarHBondContact O-N 2.87Å; E53-K67 WeakPolarHBondContact OE1-CD 3.16Å; E53-K67 IonicContact OE1-NZ 3.94Å; E53-K67 PolarHBondContact OE1-NZ 2.91Å; E53-K67 IonicContact OE2-NZ 3.86Å; K67-G71 VanDerWaalsContact CE-O 3.29Å; K67-G71 WeakPolarHBondContact CE-O 3.5Å; K67-R72 CarbonylContact C-O 3.5Å; K67-R72 WeakPolarHBondContact CA-O 3.26Å; K67-Y73 HydrophobicContact CB-CD1 3.93Å; K67-Y73 HydrophobicContact CB-CE1 3.86Å; K67-Y73 HydrophobicContact CD-CE1 3.85Å; K67-Y73 HydrophobicContact CG-CD1 4.24Å; K67-Y73 HydrophobicContact CG-CE1 4.01Å; K67-Y73 PolarHBondContact NZ-OH 2.94Å
68S95.4Very high85.6Confident5 Ų539.4 Ų39.44%0.03522%0.222CC..EExtended strand (participates in β ladder)trans-74.5167.9178.466.50000112.3L70 G71 R72S68-L70 PolarHBondContact O-N 3.32Å; S68-L70 PolarHBondContact OG-N 2.96Å; S68-G71 PolarHBondContact O-N 2.89Å; S68-R72 PolarHBondContact N-O 3.38Å; S68-R72 PolarHBondContact OG-N 2.9Å; S68-R72 PolarHBondContact OG-O 3.04Å
69H91.8Very high87.8Confident46 Ų4640.1 Ų40.121%0.21323%0.226CC..THydrogen-bonded Turntrans-56.1-13.2169.576.1-74.8000115.6A30 K46 I49 G71A30-H69 PolarHBondContact O-CE1 2.93Å; K46-H69 HydrophobicContact CG-CB 4.07Å; K46-H69 VanDerWaalsContact O-CB 3.27Å; K46-H69 WeakPolarHBondContact O-CB 3.46Å; I49-H69 PolarHBondContact O-N 2.79Å; H69-G71 VanDerWaalsContact C-N 3.33Å
70L94.4Very high89.9Confident60 Ų6035.4 Ų35.431%0.31419%0.194SC..THydrogen-bonded Turntrans-89.5-0.2175.4-59.3173.6000112.4T32 S68 R72T32-L70 HydrophobicContact CG2-CD2 4.5Å; S68-L70 PolarHBondContact O-N 3.32Å; S68-L70 PolarHBondContact OG-N 2.96Å; L70-R72 VanDerWaalsContact C-N 3.27Å; L70-R72 HydrophobicContact CB-CG 4.34Å; L70-R72 PolarHBondContact O-N 3.39Å
71G94Very high92.1Very high35 Ų3535 Ų3536%0.36118%0.184SC..SBendtrans76.612.1-173.400000114.1K67 S68 H69K67-G71 VanDerWaalsContact CE-O 3.29Å; K67-G71 WeakPolarHBondContact CE-O 3.5Å; S68-G71 PolarHBondContact O-N 2.89Å; H69-G71 VanDerWaalsContact C-N 3.33Å
72R95.8Very high93.9Very high52 Ų5234.5 Ų34.520%0.19618%0.178CC..  trans-106.5146-178.2-60.1-177-177-89.8-12.7112.3K67 S68 L70 G84 D85 S86 E87K67-R72 CarbonylContact C-O 3.5Å; K67-R72 WeakPolarHBondContact CA-O 3.26Å; S68-R72 PolarHBondContact N-O 3.38Å; S68-R72 PolarHBondContact OG-N 2.9Å; S68-R72 PolarHBondContact OG-O 3.04Å; L70-R72 VanDerWaalsContact C-N 3.27Å; L70-R72 HydrophobicContact CB-CG 4.34Å; L70-R72 PolarHBondContact O-N 3.39Å; R72-G84 WeakPolarHBondContact CB-O 3.35Å; R72-G84 WeakPolarHBondContact CD-O 3.39Å; R72-D85 PolarHBondContact NH1-O 3.48Å; R72-S86 CarbonylContact C-O 3.48Å; R72-S86 VanDerWaalsContact CA-O 3.23Å; R72-S86 WeakPolarHBondContact CA-O 3.34Å; R72-S86 WeakPolarHBondContact CB-O 3.43Å; R72-E87 IonicContact CZ-OE1 2.83Å; R72-E87 IonicContact NH1-OE1 2.71Å; R72-E87 PolarHBondContact NH1-OE1 2.85Å; R72-E87 IonicContact NH2-OE1 3.23Å; R72-E87 PolarHBondContact NH2-OE1 3.45Å
73Y96.2Very high94.8Very high20 Ų2035.4 Ų35.48%0.07819%0.185CC..EExtended strand (participates in β ladder)trans-88.3145.9-178.9-56.9-80.5000112E53 F65 L66 K67 S86 A89E53-Y73 WeakPolarHBondContact OE2-CE1 3.37Å; E53-Y73 PolarHBondContact OE2-OH 3.1Å; F65-Y73 HydrophobicContact CB-CD1 3.66Å; F65-Y73 HydrophobicContact CB-CE1 3.86Å; F65-Y73 HydrophobicContact CG-CD1 4.46Å; L66-Y73 WeakPolarHBondContact O-CA 3.49Å; K67-Y73 HydrophobicContact CB-CD1 3.93Å; K67-Y73 HydrophobicContact CB-CE1 3.86Å; K67-Y73 HydrophobicContact CD-CE1 3.85Å; K67-Y73 HydrophobicContact CG-CD1 4.24Å; K67-Y73 HydrophobicContact CG-CE1 4.01Å; K67-Y73 PolarHBondContact NZ-OH 2.94Å; Y73-S86 PolarHBondContact N-O 2.72Å; Y73-A89 HydrophobicContact CE2-CB 4.35Å
74I96.2Very high95.1Very high0 Ų035.3 Ų35.30%019%0.185CC..EExtended strand (participates in β ladder)trans-69.4135.4163.9-166.2170.8000109.3L28 I37 W50 L66 V82 T83 C93 F95 L116L28-I74 HydrophobicContact CD2-CD1 4.38Å; I37-I74 HydrophobicContact CG1-CG1 4.47Å; I37-I74 HydrophobicContact CG2-CD1 4.36Å; W50-I74 HydrophobicContact CH2-CB 4.49Å; W50-I74 HydrophobicContact CZ3-CB 4.17Å; L66-I74 HydrophobicContact CB-CG2 3.66Å; L66-I74 PolarHBondContact O-N 2.99Å; I74-V82 HydrophobicContact CD1-CG1 3.77Å; I74-V82 HydrophobicContact CG1-CG1 3.68Å; I74-T83 CarbonylContact C-O 3.5Å; I74-T83 WeakPolarHBondContact CA-O 3.21Å; I74-C93 WeakPolarHBondContact O-CA 3.47Å; I74-F95 HydrophobicContact CG2-CD2 4.15Å; I74-F95 HydrophobicContact CG2-CE2 3.64Å; I74-F95 HydrophobicContact CG2-CZ 4.26Å; I74-L116 HydrophobicContact CD1-CD1 4.34Å; I74-L116 HydrophobicContact CD1-CD2 3.77Å
75A96.3Very high95.3Very high4 Ų438.6 Ų38.63%0.03320%0.203CC..EExtended strand (participates in β ladder)trans-128.6148.9176.900000110.4V82 T83 E92A75-V82 VanDerWaalsContact O-CA 3.3Å; A75-V82 WeakPolarHBondContact O-CA 3.19Å; A75-T83 PolarHBondContact N-O 2.92Å; A75-T83 PolarHBondContact O-N 2.79Å; A75-E92 WeakPolarHBondContact CA-O 3.3Å; A75-E92 HydrophobicContact CB-CB 4.26Å
76A97.1Very high95.4Very high0 Ų039.4 Ų39.40%021%0.21CC..EExtended strand (participates in β ladder)trans-127.1127.4172.500000109.6N81 E92 F95 Y112 C125A76-N81 WeakPolarHBondContact CA-O 3.46Å; A76-E92 PolarHBondContact N-O 2.87Å; A76-E92 WeakPolarHBondContact O-CB 3.41Å; A76-F95 HydrophobicContact CB-CE1 4.36Å; A76-F95 HydrophobicContact CB-CZ 3.95Å; A76-Y112 WeakPolarHBondContact O-CE2 3.13Å; A76-C125 HydrophobicContact CB-CB 3.55Å
77D95.9Very high95.3Very high44 Ų4446 Ų4624%0.23524%0.241CC..  trans-88.9177.1177.375.214.1000112.6D79 G80 N81D77-D79 PolarHBondContact O-N 3.08Å; D77-D79 WeakPolarHBondContact OD1-CA 3.35Å; D77-D79 PolarHBondContact OD1-N 2.9Å; D77-G80 PolarHBondContact O-N 2.7Å; D77-G80 PolarHBondContact OD1-N 3.02Å; D77-N81 PolarHBondContact N-O 2.86Å; D77-N81 VanDerWaalsContact N-O 3.08Å; D77-N81 PolarHBondContact OD1-N 3.49Å; D77-N81 PolarHBondContact OD1-ND2 3.35Å; D77-N81 WeakPolarHBondContact OD2-CB 3.35Å; D77-N81 PolarHBondContact OD2-ND2 3.42Å
78K96.5Very high95.1Very high141 Ų14146.6 Ų46.661%0.61326%0.256SS*.THydrogen-bonded Turntrans-60.9-25.3179.472.2-176.3-178.61790114.3G80 Y112K78-G80 VanDerWaalsContact C-N 3.32Å; K78-Y112 HydrophobicContact CB-CD1 4.06Å; K78-Y112 HydrophobicContact CB-CE1 3.54Å
79D97.1Very high94.8Very high97 Ų9749 Ų4952%0.51928%0.276SS..THydrogen-bonded Turntrans-93-1.5-178-61.7-48.4000110.7D77 F126D77-D79 PolarHBondContact O-N 3.08Å; D77-D79 WeakPolarHBondContact OD1-CA 3.35Å; D77-D79 PolarHBondContact OD1-N 2.9Å; D79-F126 WeakPolarHBondContact O-CD2 3.34Å
80G96Very high94.8Very high3 Ų348 Ų483%0.03128%0.277CS..  trans82.711.5177.700000114.1D77 K78 C125D77-G80 PolarHBondContact O-N 2.7Å; D77-G80 PolarHBondContact OD1-N 3.02Å; K78-G80 VanDerWaalsContact C-N 3.32Å; G80-C125 WeakPolarHBondContact CA-O 3.3Å; G80-C125 PolarHBondContact O-N 3.14Å
81N97.1Very high94.7Very high88 Ų8849.1 Ų49.147%0.47129%0.288SS..  trans-70.4141.5172.9-53.5-60.4000109.5A76 D77A76-N81 WeakPolarHBondContact CA-O 3.46Å; D77-N81 PolarHBondContact N-O 2.86Å; D77-N81 VanDerWaalsContact N-O 3.08Å; D77-N81 PolarHBondContact OD1-N 3.49Å; D77-N81 PolarHBondContact OD1-ND2 3.35Å; D77-N81 WeakPolarHBondContact OD2-CB 3.35Å; D77-N81 PolarHBondContact OD2-ND2 3.42Å
82V97.3Very high94.8Very high20 Ų2051.3 Ų51.312%0.12129%0.289CS..EExtended strand (participates in β ladder)trans-116.3126.4-177178.70000109.6I37 I74 A75 L116 I123 C125I37-V82 HydrophobicContact CB-CG1 4.13Å; I37-V82 HydrophobicContact CG1-CG1 4.09Å; I37-V82 HydrophobicContact CG2-CG1 4.38Å; I74-V82 HydrophobicContact CD1-CG1 3.77Å; I74-V82 HydrophobicContact CG1-CG1 3.68Å; A75-V82 VanDerWaalsContact O-CA 3.3Å; A75-V82 WeakPolarHBondContact O-CA 3.19Å; V82-L116 HydrophobicContact CB-CD1 4.47Å; V82-L116 HydrophobicContact CG1-CD1 4.06Å; V82-L116 HydrophobicContact CG2-CD1 3.62Å; V82-I123 HydrophobicContact CB-CG2 4.43Å; V82-I123 HydrophobicContact CG1-CG2 4.28Å; V82-I123 HydrophobicContact CG2-CG2 4.42Å; V82-C125 HydrophobicContact CG2-CB 3.71Å
83T94.6Very high94.7Very high52 Ų5248.9 Ų48.932%0.31928%0.28SS..EExtended strand (participates in β ladder)trans-12516117768.50000111.4I74 A75 D85I74-T83 CarbonylContact C-O 3.5Å; I74-T83 WeakPolarHBondContact CA-O 3.21Å; A75-T83 PolarHBondContact N-O 2.92Å; A75-T83 PolarHBondContact O-N 2.79Å; T83-D85 WeakPolarHBondContact CB-OD1 3.4Å; T83-D85 PolarHBondContact OG1-OD1 2.76Å
84G94.3Very high94.6Very high3 Ų350.5 Ų50.53%0.03129%0.286CS..EExtended strand (participates in β ladder)trans-122.829.4173.100000112.8F35 R72F35-G84 PolarHBondContact O-N 3.36Å; R72-G84 WeakPolarHBondContact CB-O 3.35Å; R72-G84 WeakPolarHBondContact CD-O 3.39Å
85D94.1Very high94.6Very high74 Ų7450.5 Ų50.540%0.39629%0.286SS..EExtended strand (participates in β ladder)trans-97.4-16.7-172.960.7-18.5000114F35 R72 T83 E87F35-D85 HydrophobicContact CB-CB 3.61Å; F35-D85 HydrophobicContact CD2-CB 3.58Å; F35-D85 HydrophobicContact CE2-CB 4.39Å; F35-D85 HydrophobicContact CG-CB 3.66Å; R72-D85 PolarHBondContact NH1-O 3.48Å; T83-D85 WeakPolarHBondContact CB-OD1 3.4Å; T83-D85 PolarHBondContact OG1-OD1 2.76Å; D85-E87 PolarHBondContact O-N 2.84Å
86S93.5Very high94.4Very high32 Ų3252.1 Ų52.122%0.22430%0.296CS..EExtended strand (participates in β ladder)trans-66.6121.7-175.2-170.60000112.8R72 Y73 A88R72-S86 CarbonylContact C-O 3.48Å; R72-S86 VanDerWaalsContact CA-O 3.23Å; R72-S86 WeakPolarHBondContact CA-O 3.34Å; R72-S86 WeakPolarHBondContact CB-O 3.43Å; Y73-S86 PolarHBondContact N-O 2.72Å; S86-A88 PolarHBondContact OG-O 3.21Å
87E92.4Very high94.1Very high138 Ų13852.5 Ų52.565%0.64530%0.298SS*.SBendtrans-84.4-17.7176.5-61.4-176.5177.800112.8R72 D85R72-E87 IonicContact CZ-OE1 2.83Å; R72-E87 IonicContact NH1-OE1 2.71Å; R72-E87 PolarHBondContact NH1-OE1 2.85Å; R72-E87 IonicContact NH2-OE1 3.23Å; R72-E87 PolarHBondContact NH2-OE1 3.45Å; D85-E87 PolarHBondContact O-N 2.84Å
88A91.1Very high93.8Very high65 Ų6553.2 Ų53.254%0.53730%0.304SS..SBendtrans-122.1148.1-176.600000111.4S86 G90S86-A88 PolarHBondContact OG-O 3.21Å; A88-G90 PolarHBondContact O-N 2.84Å; A88-G90 VanDerWaalsContact O-N 3.11Å
89A89Confident93.5Very high56 Ų5646.7 Ų46.746%0.46328%0.276SS..  trans-71.1105174.100000109.5F65 Y73F65-A89 HydrophobicContact CD1-CB 3.92Å; F65-A89 HydrophobicContact CD2-CB 4.46Å; F65-A89 HydrophobicContact CE1-CB 3.69Å; F65-A89 HydrophobicContact CE2-CB 4.25Å; F65-A89 HydrophobicContact CG-CB 4.3Å; F65-A89 HydrophobicContact CZ-CB 3.87Å; Y73-A89 HydrophobicContact CE2-CB 4.35Å
90G91.5Very high93.1Very high23 Ų2343.7 Ų43.724%0.23726%0.259CS..  trans-117.1175.617900000113.3A88 E92 C93A88-G90 PolarHBondContact O-N 2.84Å; A88-G90 VanDerWaalsContact O-N 3.11Å; G90-E92 VanDerWaalsContact C-N 3.32Å; G90-E92 PolarHBondContact O-N 2.88Å; G90-C93 WeakPolarHBondContact O-CB 3.13Å; G90-C93 PolarHBondContact O-N 3.46Å
91P92.8Very high92.5Very high84 Ų8447 Ų4755%0.54528%0.276SS..G310 helixtrans-54.4-42179.6-28.537.1000114.2C93 R94 Q111P91-C93 PolarHBondContact O-N 2.74Å; P91-R94 WeakPolarHBondContact O-CB 3.43Å; P91-R94 PolarHBondContact O-N 3.47Å; P91-Q111 VanDerWaalsContact C-OE1 3.3Å
92E95.3Very high91.8Very high81 Ų8145.4 Ų45.438%0.37927%0.267SS..G310 helixtrans-70.4-12.6180-63.7-173.9144.900113.4A75 A76 G90 Y112A75-E92 WeakPolarHBondContact CA-O 3.3Å; A75-E92 HydrophobicContact CB-CB 4.26Å; A76-E92 PolarHBondContact N-O 2.87Å; A76-E92 WeakPolarHBondContact O-CB 3.41Å; G90-E92 VanDerWaalsContact C-N 3.32Å; G90-E92 PolarHBondContact O-N 2.88Å; E92-Y112 HydrophobicContact CG-CE2 4.18Å; E92-Y112 PolarHBondContact OE1-OH 2.87Å
93C95.4Very high91.2Very high2 Ų244.6 Ų44.61%0.01426%0.263CS..G310 helixtrans-93.20.1178.5-54.40000113.2F65 I74 G90 P91 F95F65-C93 HydrophobicContact CD1-CB 3.7Å; F65-C93 VanDerWaalsContact CD1-O 3.28Å; F65-C93 WeakPolarHBondContact CD1-O 3.44Å; F65-C93 HydrophobicContact CE1-CB 4.09Å; I74-C93 WeakPolarHBondContact O-CA 3.47Å; G90-C93 WeakPolarHBondContact O-CB 3.13Å; G90-C93 PolarHBondContact O-N 3.46Å; P91-C93 PolarHBondContact O-N 2.74Å; C93-F95 WeakPolarHBondContact O-CD2 3.23Å
94R94.4Very high91.1Very high54 Ų5445.2 Ų45.220%0.20426%0.26CS..  trans-89.5119.6-173.7-66.2172.467.4108.50.4110.6S55 V63 F65 P91 E110S55-R94 PolarHBondContact OG-NH1 3.48Å; V63-R94 HydrophobicContact CG1-CB 3.84Å; V63-R94 HydrophobicContact CG1-CG 4.23Å; F65-R94 HydrophobicContact CD1-CG 4.37Å; F65-R94 HydrophobicContact CE1-CB 4.5Å; F65-R94 HydrophobicContact CE1-CG 3.44Å; F65-R94 VanDerWaalsContact CE1-CG 3.44Å; F65-R94 HydrophobicContact CZ-CG 3.7Å; P91-R94 WeakPolarHBondContact O-CB 3.43Å; P91-R94 PolarHBondContact O-N 3.47Å; R94-E110 HydrophobicContact CB-CB 3.9Å; R94-E110 WeakPolarHBondContact CD-OE2 3.23Å; R94-E110 IonicContact CZ-OE1 2.74Å; R94-E110 IonicContact CZ-OE2 2.7Å; R94-E110 VanDerWaalsContact NE-CD 3.34Å; R94-E110 IonicContact NE-OE1 3.95Å; R94-E110 PolarHBondContact NE-OE1 2.8Å; R94-E110 IonicContact NE-OE2 2.94Å; R94-E110 PolarHBondContact NE-OE2 3.45Å; R94-E110 IonicContact NH2-OE1 3.2Å; R94-E110 PolarHBondContact NH2-OE1 2.86Å; R94-E110 IonicContact NH2-OE2 3.1Å; R94-E110 PolarHBondContact O-N 3.19Å
95F94.3Very high91.1Very high0 Ų045.2 Ų45.20%026%0.258CS..EExtended strand (participates in β ladder)trans-121.3132.2178.4-69-92.1000112.2V63 F64 L66 I74 A76 C93 L107 Q108 L116V63-F95 WeakPolarHBondContact CA-O 3.42Å; F64-F95 PolarHBondContact N-O 2.81Å; F64-F95 PolarHBondContact O-N 2.75Å; L66-F95 HydrophobicContact CD1-CB 4.49Å; I74-F95 HydrophobicContact CG2-CD2 4.15Å; I74-F95 HydrophobicContact CG2-CE2 3.64Å; I74-F95 HydrophobicContact CG2-CZ 4.26Å; A76-F95 HydrophobicContact CB-CE1 4.36Å; A76-F95 HydrophobicContact CB-CZ 3.95Å; C93-F95 WeakPolarHBondContact O-CD2 3.23Å; F95-L107 HydrophobicContact CB-CB 4.46Å; F95-L107 HydrophobicContact CD1-CB 3.97Å; F95-Q108 CarbonylContact C-O 3.6Å; F95-Q108 VanDerWaalsContact CA-O 3.24Å; F95-Q108 WeakPolarHBondContact CA-O 3.45Å; F95-L116 HydrophobicContact CE1-CB 4.34Å
96V92.4Very high91.2Very high38 Ų3841.8 Ų41.823%0.2324%0.24CC..EExtended strand (participates in β ladder)trans-86.2121.5167.1-1780000108.7N62 V63 Q108 E110N62-V96 WeakPolarHBondContact O-CA 3.22Å; V63-V96 HydrophobicContact CG2-CG2 4.01Å; V96-Q108 HydrophobicContact CB-CB 4.44Å; V96-Q108 PolarHBondContact N-O 2.89Å; V96-Q108 PolarHBondContact O-N 3.46Å; V96-E110 HydrophobicContact CG2-CB 4.22Å; V96-E110 HydrophobicContact CG2-CG 4.26Å
97I91.4Very high91.3Very high7 Ų740.2 Ų40.24%0.03623%0.23CC..EExtended strand (participates in β ladder)trans-93.8132.8177.6-64.4178.4000109.5L52 N62 F64 W105 L107L52-I97 HydrophobicContact CD1-CD1 3.64Å; L52-I97 HydrophobicContact CD2-CD1 4.35Å; N62-I97 PolarHBondContact ND2-O 3.39Å; N62-I97 PolarHBondContact O-N 2.86Å; F64-I97 HydrophobicContact CB-CD1 4.21Å; F64-I97 HydrophobicContact CD2-CB 4.1Å; F64-I97 HydrophobicContact CD2-CD1 3.63Å; F64-I97 HydrophobicContact CD2-CG1 3.82Å; F64-I97 HydrophobicContact CE2-CB 4.22Å; F64-I97 HydrophobicContact CE2-CD1 4.24Å; F64-I97 HydrophobicContact CE2-CG1 4.42Å; F64-I97 HydrophobicContact CG-CD1 4.07Å; I97-W105 HydrophobicContact CD1-CE3 3.99Å; I97-W105 HydrophobicContact CD1-CZ3 3.86Å; I97-W105 HydrophobicContact CG2-CB 4.22Å; I97-W105 HydrophobicContact CG2-CD2 3.53Å; I97-W105 HydrophobicContact CG2-CE3 3.59Å; I97-W105 HydrophobicContact CG2-CG 3.86Å; I97-W105 HydrophobicContact CG2-CZ3 4.24Å; I97-L107 HydrophobicContact CG1-CD2 4.4Å; I97-L107 HydrophobicContact CG1-CG 4.39Å
98T90.2Very high91.5Very high59 Ų5936 Ų3636%0.36221%0.21SC..EExtended strand (participates in β ladder)trans-124.9119.9173.1-59.20000109.7H100 W105 S106T98-H100 PolarHBondContact O-CD2 2.81Å; T98-H100 VanDerWaalsContact O-CD2 3.29Å; T98-H100 PolarHBondContact O-NE2 3.46Å; T98-W105 CarbonylContact O-C 3.59Å; T98-W105 VanDerWaalsContact O-CA 3.26Å; T98-W105 WeakPolarHBondContact O-CA 3.47Å; T98-S106 PolarHBondContact N-O 2.75Å; T98-S106 PolarHBondContact O-N 3.12Å
99A89.5Confident91.8Very high4 Ų432.9 Ų32.93%0.03318%0.184CC..EExtended strand (participates in β ladder)trans-75.5148.7170.500000111.1R104 T216 R227A99-R104 CarbonylContact C-O 3.49Å; A99-T216 HydrophobicContact CB-CG2 4.16Å; A99-R227 PolarHBondContact O-NH1 3.1Å
100H88.6Confident92.1Very high35 Ų3534 Ų3416%0.16218%0.18CC..  trans-120.7154.7-179.2-64.6-89.2000110.7T98 D102 G103 R104 S106 T216T98-H100 PolarHBondContact O-CD2 2.81Å; T98-H100 VanDerWaalsContact O-CD2 3.29Å; T98-H100 PolarHBondContact O-NE2 3.46Å; H100-D102 VanDerWaalsContact CB-OD1 3.22Å; H100-D102 WeakPolarHBondContact CB-OD1 3.38Å; H100-D102 PolarHBondContact O-N 2.79Å; H100-D102 VanDerWaalsContact O-N 3.12Å; H100-G103 PolarHBondContact O-N 2.79Å; H100-R104 WeakPolarHBondContact CB-O 3.42Å; H100-R104 PolarHBondContact CD2-O 2.93Å; H100-R104 PolarHBondContact N-O 3.42Å; H100-S106 WeakPolarHBondContact NE2-CB 3.18Å; H100-S106 PolarHBondContact NE2-N 3Å; H100-S106 PolarHBondContact NE2-OG 2.93Å; H100-T216 PolarHBondContact O-OG1 3.49Å
101D82.6Confident92.2Very high73 Ų7337.3 Ų37.339%0.3919%0.189SC..THydrogen-bonded Turntrans-68.1-11.6-178.8-55.9-28.3000113.3R188 R227 G231D101-R188 PolarHBondContact O-NH2 2.66Å; D101-R227 IonicContact OD1-CZ 2.74Å; D101-R227 VanDerWaalsContact OD1-CZ 3.23Å; D101-R227 IonicContact OD1-NE 2.69Å; D101-R227 PolarHBondContact OD1-NE 2.93Å; D101-R227 IonicContact OD1-NH2 3.67Å; D101-R227 PolarHBondContact OD1-NH2 2.83Å; D101-G231 WeakPolarHBondContact OD1-CA 3.16Å; D101-G231 PolarHBondContact OD1-N 2.95Å
102D84.1Confident92.4Very high53 Ų5336.3 Ų36.328%0.28318%0.175SC..THydrogen-bonded Turntrans-85.4-7.5178.866.21.1000114H100 R104 K135 R188H100-D102 VanDerWaalsContact CB-OD1 3.22Å; H100-D102 WeakPolarHBondContact CB-OD1 3.38Å; H100-D102 PolarHBondContact O-N 2.79Å; H100-D102 VanDerWaalsContact O-N 3.12Å; D102-R104 WeakPolarHBondContact OD1-CB 3.36Å; D102-R104 PolarHBondContact OD1-N 2.79Å; D102-K135 IonicContact OD1-NZ 3.43Å; D102-K135 WeakPolarHBondContact OD2-CD 3.42Å; D102-K135 IonicContact OD2-NZ 2.8Å; D102-K135 PolarHBondContact OD2-NZ 2.74Å; D102-R188 PolarHBondContact O-NE 2.92Å; D102-R188 PolarHBondContact O-NH2 3.11Å; D102-R188 VanDerWaalsContact O-NH2 3.09Å
103G83.8Confident92.5Very high3 Ų333.9 Ų33.93%0.03117%0.172CC..SBendtrans111.5-6.7-177.300000114.5H100 T216H100-G103 PolarHBondContact O-N 2.79Å; G103-T216 WeakPolarHBondContact CA-OG1 3.39Å
104R92.1Very high92.6Very high66 Ų6636.5 Ų36.525%0.24918%0.181CC..EExtended strand (participates in β ladder)trans-114.3168.3-166.1-60.3179.9-169.4146.73.5112.7A99 H100 D102 K135 W136A99-R104 CarbonylContact C-O 3.49Å; H100-R104 WeakPolarHBondContact CB-O 3.42Å; H100-R104 PolarHBondContact CD2-O 2.93Å; H100-R104 PolarHBondContact N-O 3.42Å; D102-R104 WeakPolarHBondContact OD1-CB 3.36Å; D102-R104 PolarHBondContact OD1-N 2.79Å; R104-K135 HydrophobicContact CB-CB 4.01Å; R104-W136 CarbonylContact C-O 3.52Å; R104-W136 VanDerWaalsContact CA-O 3.28Å; R104-W136 WeakPolarHBondContact CA-O 3.46Å; R104-W136 WeakPolarHBondContact CB-O 3.38Å
105W94.8Very high92.8Very high2 Ų235.9 Ų35.91%0.00818%0.179CC..EExtended strand (participates in β ladder)trans-112.5152172.5-69.52.4000111.2F18 L20 I97 T98 K135 W136 V138 L217 F219F18-W105 HydrophobicContact CE2-CZ3 4.17Å; L20-W105 HydrophobicContact CD2-CE3 4.31Å; I97-W105 HydrophobicContact CD1-CE3 3.99Å; I97-W105 HydrophobicContact CD1-CZ3 3.86Å; I97-W105 HydrophobicContact CG2-CB 4.22Å; I97-W105 HydrophobicContact CG2-CD2 3.53Å; I97-W105 HydrophobicContact CG2-CE3 3.59Å; I97-W105 HydrophobicContact CG2-CG 3.86Å; I97-W105 HydrophobicContact CG2-CZ3 4.24Å; T98-W105 CarbonylContact O-C 3.59Å; T98-W105 VanDerWaalsContact O-CA 3.26Å; T98-W105 WeakPolarHBondContact O-CA 3.47Å; W105-K135 CarbonylContact O-C 3.59Å; W105-K135 VanDerWaalsContact O-CA 3.32Å; W105-K135 WeakPolarHBondContact O-CA 3.23Å; W105-W136 PolarHBondContact N-O 3.43Å; W105-W136 PolarHBondContact O-N 3.08Å; W105-V138 HydrophobicContact CD2-CG2 3.22Å; W105-V138 HydrophobicContact CE3-CG2 3.31Å; W105-V138 HydrophobicContact CG-CG2 3.8Å; W105-V138 HydrophobicContact CH2-CB 4.33Å; W105-V138 HydrophobicContact CH2-CG1 3.93Å; W105-V138 HydrophobicContact CH2-CG2 3.58Å; W105-V138 HydrophobicContact CZ2-CB 4.28Å; W105-V138 HydrophobicContact CZ2-CG1 4.2Å; W105-V138 HydrophobicContact CZ2-CG2 3.58Å; W105-V138 HydrophobicContact CZ3-CG1 4.36Å; W105-V138 HydrophobicContact CZ3-CG2 3.48Å; W105-V138 VanDerWaalsContact CZ3-CG2 3.48Å; W105-L217 VanDerWaalsContact CE2-O 3.27Å; W105-L217 VanDerWaalsContact CZ2-O 3.24Å; W105-L217 WeakPolarHBondContact CZ2-O 3.35Å; W105-L217 PolarHBondContact NE1-O 3.28Å; W105-F219 AromaticContact CH2-CD2 3.39Å; W105-F219 HydrophobicContact CH2-CD2 3.39Å; W105-F219 AromaticContact CH2-CE2 3.53Å; W105-F219 HydrophobicContact CH2-CE2 3.53Å; W105-F219 AromaticContact CZ2-CD2 3.69Å; W105-F219 HydrophobicContact CZ2-CD2 3.69Å; W105-F219 AromaticContact CZ2-CE2 3.8Å; W105-F219 HydrophobicContact CZ2-CE2 3.8Å
106S95.9Very high93Very high2 Ų235.9 Ų35.91%0.01418%0.179CC..EExtended strand (participates in β ladder)trans-114.1144.815756.10000109.6T98 H100 E134T98-S106 PolarHBondContact N-O 2.75Å; T98-S106 PolarHBondContact O-N 3.12Å; H100-S106 WeakPolarHBondContact NE2-CB 3.18Å; H100-S106 PolarHBondContact NE2-N 3Å; H100-S106 PolarHBondContact NE2-OG 2.93Å; S106-E134 WeakPolarHBondContact CA-O 3.43Å
107L96.4Very high93.2Very high0 Ų034.1 Ų34.10%017%0.168CC..EExtended strand (participates in β ladder)trans-112.4118.3176-57.893.2000108.4L20 L66 F95 I97 Y115 L116 W136L20-L107 HydrophobicContact CD1-CD1 4.22Å; L20-L107 HydrophobicContact CD1-CD2 4.29Å; L66-L107 HydrophobicContact CD1-CD2 3.73Å; L66-L107 HydrophobicContact CD2-CD2 3.54Å; L66-L107 HydrophobicContact CG-CD2 4.31Å; F95-L107 HydrophobicContact CB-CB 4.46Å; F95-L107 HydrophobicContact CD1-CB 3.97Å; I97-L107 HydrophobicContact CG1-CD2 4.4Å; I97-L107 HydrophobicContact CG1-CG 4.39Å; L107-Y115 WeakPolarHBondContact O-CA 3.28Å; L107-L116 HydrophobicContact CB-CB 4.2Å; L107-L116 HydrophobicContact CB-CD2 4.41Å; L107-L116 PolarHBondContact O-N 2.78Å; L107-W136 HydrophobicContact CD1-CB 4.38Å; L107-W136 VanDerWaalsContact CD1-CD1 3.47Å; L107-W136 HydrophobicContact CD1-CG 3.98Å
108Q97.1Very high93.5Very high48 Ų4834.3 Ų34.322%0.22417%0.172CC..EExtended strand (participates in β ladder)trans-106.7128.2177.8-167179.721.900109.4F95 V96 E110 G113 R114 Y115F95-Q108 CarbonylContact C-O 3.6Å; F95-Q108 VanDerWaalsContact CA-O 3.24Å; F95-Q108 WeakPolarHBondContact CA-O 3.45Å; V96-Q108 HydrophobicContact CB-CB 4.44Å; V96-Q108 PolarHBondContact N-O 2.89Å; V96-Q108 PolarHBondContact O-N 3.46Å; Q108-E110 PolarHBondContact O-N 3.31Å; Q108-G113 VanDerWaalsContact NE2-C 3.34Å; Q108-G113 PolarHBondContact NE2-O 3.45Å; Q108-R114 CarbonylContact C-O 3.59Å; Q108-R114 VanDerWaalsContact CA-O 3.31Å; Q108-R114 WeakPolarHBondContact CA-O 3.43Å; Q108-Y115 HydrophobicContact CB-CD1 3.74Å; Q108-Y115 HydrophobicContact CB-CE1 3.59Å; Q108-Y115 HydrophobicContact CG-CD1 4.04Å; Q108-Y115 HydrophobicContact CG-CE1 3.8Å; Q108-Y115 HydrophobicContact CG-CE2 4.45Å; Q108-Y115 HydrophobicContact CG-CG 4.47Å; Q108-Y115 PolarHBondContact NE2-OH 2.99Å
109S96.6Very high93.8Very high1 Ų133.4 Ų33.41%0.00717%0.167CC..EExtended strand (participates in β ladder)trans-57.2121.4167.2169.60000108.9Q111 Y112 G113 R114S109-Q111 VanDerWaalsContact C-N 3.28Å; S109-Q111 PolarHBondContact O-N 2.8Å; S109-Y112 WeakPolarHBondContact OG-CD2 3.48Å; S109-Y112 PolarHBondContact OG-N 3.37Å; S109-G113 WeakPolarHBondContact O-CA 3.46Å; S109-G113 PolarHBondContact O-N 3.01Å; S109-R114 PolarHBondContact N-O 3.25Å
110E95.1Very high94.1Very high78 Ų7836.7 Ų36.736%0.36418%0.181SC..THydrogen-bonded Turntrans-62.9-39.6179.9-172.2-156-124.600110.5V63 R94 V96 Q108V63-E110 HydrophobicContact CG2-CG 4.35Å; V63-E110 WeakPolarHBondContact CG2-OE1 3.41Å; R94-E110 HydrophobicContact CB-CB 3.9Å; R94-E110 WeakPolarHBondContact CD-OE2 3.23Å; R94-E110 IonicContact CZ-OE1 2.74Å; R94-E110 IonicContact CZ-OE2 2.7Å; R94-E110 VanDerWaalsContact NE-CD 3.34Å; R94-E110 IonicContact NE-OE1 3.95Å; R94-E110 PolarHBondContact NE-OE1 2.8Å; R94-E110 IonicContact NE-OE2 2.94Å; R94-E110 PolarHBondContact NE-OE2 3.45Å; R94-E110 IonicContact NH2-OE1 3.2Å; R94-E110 PolarHBondContact NH2-OE1 2.86Å; R94-E110 IonicContact NH2-OE2 3.1Å; R94-E110 PolarHBondContact O-N 3.19Å; V96-E110 HydrophobicContact CG2-CB 4.22Å; V96-E110 HydrophobicContact CG2-CG 4.26Å; Q108-E110 PolarHBondContact O-N 3.31Å
111Q94.2Very high94.4Very high93 Ų9341 Ų4144%0.43521%0.206SC..THydrogen-bonded Turntrans-72.2-39.3-176.8-173.7172.2-3.100113.2P91 S109P91-Q111 VanDerWaalsContact C-OE1 3.3Å; S109-Q111 VanDerWaalsContact C-N 3.28Å; S109-Q111 PolarHBondContact O-N 2.8Å
112Y96.7Very high95.1Very high63 Ų6345.4 Ų45.425%0.24722%0.217CC..THydrogen-bonded Turntrans-109.7-8.3-171.2-56.4-61.9000114.4A76 K78 E92 S109 R114A76-Y112 WeakPolarHBondContact O-CE2 3.13Å; K78-Y112 HydrophobicContact CB-CD1 4.06Å; K78-Y112 HydrophobicContact CB-CE1 3.54Å; E92-Y112 HydrophobicContact CG-CE2 4.18Å; E92-Y112 PolarHBondContact OE1-OH 2.87Å; S109-Y112 WeakPolarHBondContact OG-CD2 3.48Å; S109-Y112 PolarHBondContact OG-N 3.37Å; Y112-R114 PolarHBondContact O-N 2.93Å
113G96.3Very high95.7Very high30 Ų3043.5 Ų43.531%0.30921%0.206SC..  trans64.518.2-179.900000114.1Q108 S109Q108-G113 VanDerWaalsContact NE2-C 3.34Å; Q108-G113 PolarHBondContact NE2-O 3.45Å; S109-G113 WeakPolarHBondContact O-CA 3.46Å; S109-G113 PolarHBondContact O-N 3.01Å
114R98.1Very high96.4Very high58 Ų5847.5 Ų47.522%0.21923%0.226CC..PPolyproline II helixtrans-102.4151.7-179.7-59.1-53.9-177.6106.55.6111.7Q108 S109 Y112 C125 F126 A127Q108-R114 CarbonylContact C-O 3.59Å; Q108-R114 VanDerWaalsContact CA-O 3.31Å; Q108-R114 WeakPolarHBondContact CA-O 3.43Å; S109-R114 PolarHBondContact N-O 3.25Å; Y112-R114 PolarHBondContact O-N 2.93Å; R114-C125 WeakPolarHBondContact CB-O 3.31Å; R114-C125 PolarHBondContact O-SG 3.32Å; R114-F126 WeakPolarHBondContact CD-O 3.27Å; R114-F126 PolarHBondContact NH1-O 2.69Å; R114-A127 CarbonylContact C-O 3.53Å; R114-A127 VanDerWaalsContact CA-O 3.3Å; R114-A127 WeakPolarHBondContact CA-O 3.34Å
115Y98.5Very high96.7Very high41 Ų4144.5 Ų44.516%0.16122%0.215CC..EExtended strand (participates in β ladder)trans-98.8136.2-176.4-64-83.1000112.6L107 Q108 C125 A127 V130L107-Y115 WeakPolarHBondContact O-CA 3.28Å; Q108-Y115 HydrophobicContact CB-CD1 3.74Å; Q108-Y115 HydrophobicContact CB-CE1 3.59Å; Q108-Y115 HydrophobicContact CG-CD1 4.04Å; Q108-Y115 HydrophobicContact CG-CE1 3.8Å; Q108-Y115 HydrophobicContact CG-CE2 4.45Å; Q108-Y115 HydrophobicContact CG-CG 4.47Å; Q108-Y115 PolarHBondContact NE2-OH 2.99Å; Y115-C125 WeakPolarHBondContact O-CA 3.32Å; Y115-A127 WeakPolarHBondContact CD2-O 3.48Å; Y115-A127 PolarHBondContact N-O 3.02Å; Y115-V130 HydrophobicContact CD1-CG2 3.49Å; Y115-V130 VanDerWaalsContact CD1-CG2 3.49Å; Y115-V130 HydrophobicContact CD2-CG2 3.99Å; Y115-V130 HydrophobicContact CE1-CG2 3.41Å; Y115-V130 VanDerWaalsContact CE1-CG2 3.41Å; Y115-V130 HydrophobicContact CE2-CG2 3.94Å; Y115-V130 HydrophobicContact CG-CG2 3.77Å
116L98.4Very high96.8Very high0 Ų048.8 Ų48.80%023%0.234CC..EExtended strand (participates in β ladder)trans-76.9123.5174.4179.470.8000110.4I74 V82 F95 L107 I123 I124 C125 W136I74-L116 HydrophobicContact CD1-CD1 4.34Å; I74-L116 HydrophobicContact CD1-CD2 3.77Å; V82-L116 HydrophobicContact CB-CD1 4.47Å; V82-L116 HydrophobicContact CG1-CD1 4.06Å; V82-L116 HydrophobicContact CG2-CD1 3.62Å; F95-L116 HydrophobicContact CE1-CB 4.34Å; L107-L116 HydrophobicContact CB-CB 4.2Å; L107-L116 HydrophobicContact CB-CD2 4.41Å; L107-L116 PolarHBondContact O-N 2.78Å; L116-I123 HydrophobicContact CD1-CG2 3.71Å; L116-I124 WeakPolarHBondContact CA-O 3.39Å; L116-C125 HydrophobicContact CB-CB 4.4Å; L116-C125 HydrophobicContact CD1-CB 4.14Å; L116-W136 PolarHBondContact O-NE1 3.2Å
117G98Very high96.9Very high0 Ų049.9 Ų49.90%024%0.243CC..EExtended strand (participates in β ladder)trans-159.8176.5-179.500000112.8I124 A133G117-I124 PolarHBondContact N-O 3.04Å; G117-I124 PolarHBondContact O-N 2.93Å; G117-I124 VanDerWaalsContact O-O 3.06Å; G117-A133 WeakPolarHBondContact CA-O 3.35Å
118G96.8Very high96.9Very high11 Ų1156.6 Ų56.611%0.11328%0.275CS..EExtended strand (participates in β ladder)trans132.7-175.6172.300000115.1N22 R122 A133N22-G118 PolarHBondContact ND2-O 3.5Å; G118-R122 WeakPolarHBondContact CA-O 3.44Å; G118-A133 PolarHBondContact N-O 2.79Å; G118-A133 VanDerWaalsContact N-O 3.1Å
119T96.8Very high96.9Very high41 Ų4159.5 Ų59.525%0.25230%0.296SS..EExtended strand (participates in β ladder)trans-137.9146.8-175.855.50000110.7D121 R122T119-D121 PolarHBondContact O-N 2.82Å; T119-R122 PolarHBondContact O-N 2.77Å
120E95.8Very high97Very high73 Ų7361.7 Ų61.734%0.34131%0.309SS..BIsolated β-bridgetrans52.9-129.2178.1-56.4-61.815400110.9N38 A39 S40 R122N38-E120 CarbonylContact C-O 3.48Å; N38-E120 VanDerWaalsContact CA-O 3.32Å; N38-E120 WeakPolarHBondContact CA-O 3.48Å; N38-E120 VanDerWaalsContact CB-O 3.31Å; N38-E120 WeakPolarHBondContact CB-O 3.39Å; A39-E120 PolarHBondContact N-O 3.29Å; A39-E120 WeakPolarHBondContact O-CA 3.37Å; A39-E120 PolarHBondContact O-N 2.74Å; S40-E120 VanDerWaalsContact CA-OE2 3.28Å; S40-E120 WeakPolarHBondContact CA-OE2 3.49Å; S40-E120 WeakPolarHBondContact CB-OE2 3.42Å; S40-E120 WeakPolarHBondContact OG-CA 3.45Å; S40-E120 PolarHBondContact OG-OE2 3.5Å; E120-R122 VanDerWaalsContact C-N 3.27Å; E120-R122 PolarHBondContact O-N 2.78Å
121D95.2Very high97Very high126 Ų12660.8 Ų60.867%0.67431%0.311SS*.THydrogen-bonded Turntrans-80.50.217963.6-28.6000114.6T119 I123T119-D121 PolarHBondContact O-N 2.82Å; D121-I123 PolarHBondContact O-N 3.29Å
122R96Very high97Very high165 Ų16560.6 Ų60.662%0.62332%0.316SS*.EExtended strand (participates in β ladder)trans-104.358.3-176.6-60.8175.9-64-179.42.1111.3G118 T119 E120G118-R122 WeakPolarHBondContact CA-O 3.44Å; T119-R122 PolarHBondContact O-N 2.77Å; E120-R122 VanDerWaalsContact C-N 3.27Å; E120-R122 PolarHBondContact O-N 2.78Å
123I97.8Very high97Very high12 Ų1258.9 Ų58.96%0.06232%0.315CS..EExtended strand (participates in β ladder)trans-88.2123172-60.1-54.2000109.3L28 I37 A39 V82 L116 D121 W136L28-I123 HydrophobicContact CD1-CG2 4.45Å; I37-I123 HydrophobicContact CG2-CB 4.46Å; I37-I123 HydrophobicContact CG2-CG2 4.09Å; A39-I123 HydrophobicContact CB-CD1 3.83Å; A39-I123 HydrophobicContact CB-CG1 4.43Å; V82-I123 HydrophobicContact CB-CG2 4.43Å; V82-I123 HydrophobicContact CG1-CG2 4.28Å; V82-I123 HydrophobicContact CG2-CG2 4.42Å; L116-I123 HydrophobicContact CD1-CG2 3.71Å; D121-I123 PolarHBondContact O-N 3.29Å; I123-W136 HydrophobicContact CD1-CH2 3.87Å; I123-W136 HydrophobicContact CD1-CZ2 4.35Å
124I97.8Very high97.1Very high88 Ų8858.4 Ų58.445%0.45131%0.305SS..EExtended strand (participates in β ladder)trans-139159.6-179.261.8169.2000110.5L116 G117 F126L116-I124 WeakPolarHBondContact CA-O 3.39Å; G117-I124 PolarHBondContact N-O 3.04Å; G117-I124 PolarHBondContact O-N 2.93Å; G117-I124 VanDerWaalsContact O-O 3.06Å; I124-F126 HydrophobicContact CD1-CB 4.4Å
125C98.3Very high97.1Very high2 Ų257.5 Ų57.51%0.01430%0.302CS..EExtended strand (participates in β ladder)trans-124.263.3176.5-173.20000110.6A76 G80 V82 R114 Y115 L116A76-C125 HydrophobicContact CB-CB 3.55Å; G80-C125 WeakPolarHBondContact CA-O 3.3Å; G80-C125 PolarHBondContact O-N 3.14Å; V82-C125 HydrophobicContact CG2-CB 3.71Å; R114-C125 WeakPolarHBondContact CB-O 3.31Å; R114-C125 PolarHBondContact O-SG 3.32Å; Y115-C125 WeakPolarHBondContact O-CA 3.32Å; L116-C125 HydrophobicContact CB-CB 4.4Å; L116-C125 HydrophobicContact CD1-CB 4.14Å
126F98.1Very high97Very high93 Ų9355.6 Ų55.641%0.40830%0.295SS..EExtended strand (participates in β ladder)trans-127.7-7.8-173.8-157-113.4000114.7D79 R114 I124 Q128D79-F126 WeakPolarHBondContact O-CD2 3.34Å; R114-F126 WeakPolarHBondContact CD-O 3.27Å; R114-F126 PolarHBondContact NH1-O 2.69Å; I124-F126 HydrophobicContact CD1-CB 4.4Å; F126-Q128 PolarHBondContact O-N 2.82Å
127A97.6Very high96.8Very high25 Ų2555.6 Ų55.621%0.20730%0.295CS..EExtended strand (participates in β ladder)trans-67.1136.5-178.600000111R114 Y115 E134R114-A127 CarbonylContact C-O 3.53Å; R114-A127 VanDerWaalsContact CA-O 3.3Å; R114-A127 WeakPolarHBondContact CA-O 3.34Å; Y115-A127 WeakPolarHBondContact CD2-O 3.48Å; Y115-A127 PolarHBondContact N-O 3.02Å; A127-E134 HydrophobicContact CB-CG 3.81Å
128Q96.9Very high96.5Very high141 Ų14156 Ų5666%0.65930%0.297SS*.SBendtrans-85.5-21.2176.2-65.6-177.920.100112.6F126F126-Q128 PolarHBondContact O-N 2.82Å
129T96.8Very high96.3Very high109 Ų10955.4 Ų55.467%0.66929%0.292SS*.SBendtrans-133.5152.6179.456.30000109.5S131T129-S131 PolarHBondContact O-N 2.6Å
130V97.4Very high95.9Very high47 Ų4753.5 Ų53.529%0.28528%0.28SS..  trans-79.9116.7179.3179.10000109.5Y115 E134 K135Y115-V130 HydrophobicContact CD1-CG2 3.49Å; Y115-V130 VanDerWaalsContact CD1-CG2 3.49Å; Y115-V130 HydrophobicContact CD2-CG2 3.99Å; Y115-V130 HydrophobicContact CE1-CG2 3.41Å; Y115-V130 VanDerWaalsContact CE1-CG2 3.41Å; Y115-V130 HydrophobicContact CE2-CG2 3.94Å; Y115-V130 HydrophobicContact CG-CG2 3.77Å; V130-E134 HydrophobicContact CG1-CB 4.21Å; V130-K135 HydrophobicContact CG1-CD 4.38Å; V130-K135 HydrophobicContact CG1-CG 3.74Å
131S95.7Very high95.4Very high59 Ų5950.1 Ų50.141%0.41327%0.265SS..  trans-101.8-169.9165.184.80000110.7T129 A133 E134T129-S131 PolarHBondContact O-N 2.6Å; S131-A133 PolarHBondContact O-N 2.81Å; S131-A133 PolarHBondContact OG-N 3.01Å; S131-A133 VanDerWaalsContact OG-N 3.1Å; S131-E134 WeakPolarHBondContact CA-OE2 3.32Å; S131-E134 VanDerWaalsContact CB-OE2 3.24Å; S131-E134 WeakPolarHBondContact CB-OE2 3.35Å; S131-E134 PolarHBondContact N-OE2 2.65Å; S131-E134 PolarHBondContact O-N 3.2Å; S131-E134 PolarHBondContact OG-OE2 3Å
132V95.1Very high94.8Very high89 Ų8945 Ų4554%0.53924%0.237SC..G310 helixtrans-63.2-29.1172.4179.80000111.5C23 E134 K135C23-V132 HydrophobicContact CB-CG1 3.7Å; C23-V132 WeakPolarHBondContact CB-O 3.39Å; V132-E134 VanDerWaalsContact C-N 3.33Å; V132-E134 PolarHBondContact O-N 2.6Å; V132-K135 PolarHBondContact O-N 3.5Å
133A96.9Very high94.5Very high26 Ų2637.5 Ų37.522%0.21521%0.209CC..G310 helixtrans-72.5-22.6-178.300000114G117 G118 S131G117-A133 WeakPolarHBondContact CA-O 3.35Å; G118-A133 PolarHBondContact N-O 2.79Å; G118-A133 VanDerWaalsContact N-O 3.1Å; S131-A133 PolarHBondContact O-N 2.81Å; S131-A133 PolarHBondContact OG-N 3.01Å; S131-A133 VanDerWaalsContact OG-N 3.1Å
134E97.9Very high94.2Very high20 Ų2036.9 Ų36.99%0.09321%0.206CC..G310 helixtrans-96.78.1179.1-67.765.9-123.600112.5S106 A127 V130 S131 V132S106-E134 WeakPolarHBondContact CA-O 3.43Å; A127-E134 HydrophobicContact CB-CG 3.81Å; V130-E134 HydrophobicContact CG1-CB 4.21Å; S131-E134 WeakPolarHBondContact CA-OE2 3.32Å; S131-E134 VanDerWaalsContact CB-OE2 3.24Å; S131-E134 WeakPolarHBondContact CB-OE2 3.35Å; S131-E134 PolarHBondContact N-OE2 2.65Å; S131-E134 PolarHBondContact O-N 3.2Å; S131-E134 PolarHBondContact OG-OE2 3Å; V132-E134 VanDerWaalsContact C-N 3.33Å; V132-E134 PolarHBondContact O-N 2.6Å
135K96.6Very high94.1Very high40 Ų4032.7 Ų32.717%0.17418%0.184CC..  trans-104.4127.8178.9-74.5-177.5169.3-169.50111.6D102 R104 W105 V130 V132D102-K135 IonicContact OD1-NZ 3.43Å; D102-K135 WeakPolarHBondContact OD2-CD 3.42Å; D102-K135 IonicContact OD2-NZ 2.8Å; D102-K135 PolarHBondContact OD2-NZ 2.74Å; R104-K135 HydrophobicContact CB-CB 4.01Å; W105-K135 CarbonylContact O-C 3.59Å; W105-K135 VanDerWaalsContact O-CA 3.32Å; W105-K135 WeakPolarHBondContact O-CA 3.23Å; V130-K135 HydrophobicContact CG1-CD 4.38Å; V130-K135 HydrophobicContact CG1-CG 3.74Å; V132-K135 PolarHBondContact O-N 3.5Å
136W96.6Very high94Very high0 Ų032.8 Ų32.80%018%0.184CC..EExtended strand (participates in β ladder)trans-121.9132.9-175-5985.4000111L20 I21 N22 L28 A39 R104 W105 L107 L116 I123L20-W136 HydrophobicContact CB-CB 4.32Å; L20-W136 HydrophobicContact CB-CD2 4.36Å; L20-W136 HydrophobicContact CB-CE3 3.78Å; L20-W136 HydrophobicContact CB-CZ3 4.49Å; L20-W136 HydrophobicContact CD2-CB 3.92Å; I21-W136 CarbonylContact O-C 3.56Å; I21-W136 VanDerWaalsContact O-CA 3.28Å; I21-W136 WeakPolarHBondContact O-CA 3.41Å; N22-W136 HydrophobicContact CB-CD2 4.5Å; N22-W136 HydrophobicContact CB-CE3 3.8Å; N22-W136 HydrophobicContact CB-CH2 3.84Å; N22-W136 HydrophobicContact CB-CZ3 3.46Å; N22-W136 VanDerWaalsContact CB-CZ3 3.46Å; L28-W136 HydrophobicContact CB-CE3 4.47Å; L28-W136 HydrophobicContact CB-CH2 4.44Å; L28-W136 HydrophobicContact CB-CZ3 3.85Å; L28-W136 HydrophobicContact CD1-CH2 3.75Å; L28-W136 HydrophobicContact CD1-CZ2 4.49Å; L28-W136 HydrophobicContact CD1-CZ3 4.04Å; L28-W136 HydrophobicContact CG-CZ3 4.47Å; A39-W136 HydrophobicContact CB-CH2 4.14Å; A39-W136 HydrophobicContact CB-CZ3 4.18Å; R104-W136 CarbonylContact C-O 3.52Å; R104-W136 VanDerWaalsContact CA-O 3.28Å; R104-W136 WeakPolarHBondContact CA-O 3.46Å; R104-W136 WeakPolarHBondContact CB-O 3.38Å; W105-W136 PolarHBondContact N-O 3.43Å; W105-W136 PolarHBondContact O-N 3.08Å; L107-W136 HydrophobicContact CD1-CB 4.38Å; L107-W136 VanDerWaalsContact CD1-CD1 3.47Å; L107-W136 HydrophobicContact CD1-CG 3.98Å; L116-W136 PolarHBondContact O-NE1 3.2Å; I123-W136 HydrophobicContact CD1-CH2 3.87Å; I123-W136 HydrophobicContact CD1-CZ2 4.35Å
137S94Very high93.9Very high1 Ų128.6 Ų28.61%0.00717%0.166CC..EExtended strand (participates in β ladder)trans-88.5135.4172.6-39.30000109.2L20 I21 Q187L20-S137 WeakPolarHBondContact CA-O 3.17Å; I21-S137 PolarHBondContact N-O 2.61Å; I21-S137 PolarHBondContact O-N 3.1Å; S137-Q187 VanDerWaalsContact CB-OE1 3.22Å; S137-Q187 WeakPolarHBondContact OG-CB 3.26Å; S137-Q187 WeakPolarHBondContact OG-CG 3.42Å; S137-Q187 PolarHBondContact OG-OE1 3.18Å
138V92.6Very high94Very high7 Ų727.4 Ų27.44%0.04216%0.157CC..EExtended strand (participates in β ladder)trans-93.7128.2-178.5-179.50000109.7F18 L20 W105 F184 Y189 F219F18-V138 HydrophobicContact CB-CG1 4.02Å; F18-V138 HydrophobicContact CD2-CG1 3.97Å; F18-V138 HydrophobicContact CG-CG1 4.19Å; L20-V138 HydrophobicContact CD2-CG2 3.86Å; W105-V138 HydrophobicContact CD2-CG2 3.22Å; W105-V138 HydrophobicContact CE3-CG2 3.31Å; W105-V138 HydrophobicContact CG-CG2 3.8Å; W105-V138 HydrophobicContact CH2-CB 4.33Å; W105-V138 HydrophobicContact CH2-CG1 3.93Å; W105-V138 HydrophobicContact CH2-CG2 3.58Å; W105-V138 HydrophobicContact CZ2-CB 4.28Å; W105-V138 HydrophobicContact CZ2-CG1 4.2Å; W105-V138 HydrophobicContact CZ2-CG2 3.58Å; W105-V138 HydrophobicContact CZ3-CG1 4.36Å; W105-V138 HydrophobicContact CZ3-CG2 3.48Å; W105-V138 VanDerWaalsContact CZ3-CG2 3.48Å; V138-F184 WeakPolarHBondContact O-CE2 3.38Å; V138-Y189 WeakPolarHBondContact O-CE2 3.36Å; V138-F219 HydrophobicContact CG1-CE2 4.34Å
139H91.7Very high94Very high0 Ų022.9 Ų22.90%014%0.135CC..EExtended strand (participates in β ladder)trans-124.2102.7178.6-170.8-141.1000109.7F18 G19 I21 Y27 A141 F184 Y189 S412F18-H139 CarbonylContact C-O 3.49Å; F18-H139 VanDerWaalsContact CA-O 3.23Å; F18-H139 WeakPolarHBondContact CA-O 3.34Å; F18-H139 WeakPolarHBondContact CB-O 3.31Å; G19-H139 PolarHBondContact N-O 2.83Å; G19-H139 PolarHBondContact O-N 2.87Å; I21-H139 HydrophobicContact CD1-CB 3.99Å; Y27-H139 HydrophobicContact CE1-CB 4.17Å; Y27-H139 AromaticContact CE1-ND1 3.85Å; Y27-H139 AromaticContact CZ-ND1 3.8Å; Y27-H139 PolarHBondContact OH-CE1 2.88Å; Y27-H139 PolarHBondContact OH-ND1 2.89Å; H139-A141 PolarHBondContact O-N 2.91Å; H139-F184 HydrophobicContact CB-CE1 4.47Å; H139-F184 HydrophobicContact CB-CZ 4.25Å; H139-F184 AromaticContact CD2-CD1 3.45Å; H139-F184 VanDerWaalsContact CD2-CD1 3.45Å; H139-F184 WeakPolarHBondContact CD2-CD1 3.23Å; H139-F184 AromaticContact CD2-CD2 3.99Å; H139-F184 AromaticContact CD2-CE1 3.73Å; H139-F184 AromaticContact CD2-CG 3.55Å; H139-F184 AromaticContact NE2-CD1 3.69Å; H139-F184 AromaticContact NE2-CG 3.98Å; H139-Y189 WeakPolarHBondContact CA-OH 3.5Å; H139-Y189 PolarHBondContact CD2-OH 3.02Å; H139-S412 PolarHBondContact CE1-O 2.81Å
140I89.3Confident94.1Very high1 Ų117.7 Ų17.71%0.00510%0.103CC..EExtended strand (participates in β ladder)trans-56.6136.6179.476.2-169.5000110.7M142 L182 Y189 L217 F219I140-M142 HydrophobicContact CB-CG 4.13Å; I140-M142 HydrophobicContact CD1-CG 3.87Å; I140-M142 HydrophobicContact CG1-CG 4.02Å; I140-L182 HydrophobicContact CD1-CB 4.41Å; I140-L182 HydrophobicContact CD1-CD1 3.83Å; I140-Y189 HydrophobicContact CD1-CE1 3.81Å; I140-Y189 HydrophobicContact CG1-CE1 4.06Å; I140-Y189 WeakPolarHBondContact CG1-OH 3.24Å; I140-Y189 HydrophobicContact CG2-CE2 4.23Å; I140-Y189 PolarHBondContact N-OH 2.84Å; I140-L217 HydrophobicContact CG2-CD1 3.63Å; I140-F219 HydrophobicContact CG2-CZ 4.4Å
141A84.9Confident94Very high2 Ų217.7 Ų17.72%0.01710%0.103CC..  trans-101.613.3174.400000111.4Q17 M44 I49 H139 R392Q17-A141 HydrophobicContact CB-CB 3.99Å; Q17-A141 PolarHBondContact O-N 3.39Å; M44-A141 HydrophobicContact CE-CB 3.76Å; M44-A141 HydrophobicContact SD-CB 4.1Å; I49-A141 HydrophobicContact CD1-CB 4.43Å; I49-A141 HydrophobicContact CG1-CB 4.24Å; H139-A141 PolarHBondContact O-N 2.91Å; A141-R392 PolarHBondContact O-NH1 3.36Å
142M82.1Confident94Very high19 Ų1917.8 Ų17.89%0.09410%0.101CC..SBendtrans-89164.6168.368-178.866.300110.7L14 I16 I140 L259L14-M142 HydrophobicContact CD2-CB 4.38Å; L14-M142 HydrophobicContact CD2-CE 4.16Å; L14-M142 HydrophobicContact CD2-SD 4.36Å; I16-M142 HydrophobicContact CG1-CE 4.3Å; I16-M142 HydrophobicContact CG2-CE 4.38Å; I140-M142 HydrophobicContact CB-CG 4.13Å; I140-M142 HydrophobicContact CD1-CG 3.87Å; I140-M142 HydrophobicContact CG1-CG 4.02Å; M142-L259 HydrophobicContact SD-CD1 4.33Å
143H89.8Confident94.1Very high6 Ų617.5 Ų17.53%0.0289%0.09CC..  trans-60.8132.6171.5-162.8-92.8000110.4Q145 V390 E497 Y498H143-Q145 VanDerWaalsContact C-N 3.33Å; H143-Q145 PolarHBondContact ND1-N 2.69Å; H143-Q145 PolarHBondContact O-N 3.09Å; H143-V390 PolarHBondContact NE2-O 2.87Å; H143-E497 HydrophobicContact CB-CG 4.25Å; H143-Y498 PolarHBondContact CE1-O 2.84Å; H143-Y498 PolarHBondContact CE1-OXT 3.23Å; H143-Y498 PolarHBondContact ND1-O 3.16Å; H143-Y498 WeakPolarHBondContact NE2-CA 3.46Å
144P92.9Very high94.1Very high0 Ų023 Ų230%011%0.11CC..SBendtrans-78.6-12.7-172.230.3-36.7000114.5L182 V390 Y414P144-L182 HydrophobicContact CB-CB 4.36Å; P144-L182 VanDerWaalsContact CB-O 3.23Å; P144-L182 WeakPolarHBondContact CB-O 3.34Å; P144-L182 PolarHBondContact O-N 3.41Å; P144-V390 HydrophobicContact CG-CB 4.06Å; P144-V390 HydrophobicContact CG-CG1 3.82Å; P144-V390 HydrophobicContact CG-CG2 3.98Å; P144-Y414 HydrophobicContact CB-CE1 3.9Å; P144-Y414 HydrophobicContact CB-CE2 4Å; P144-Y414 HydrophobicContact CG-CD1 3.94Å; P144-Y414 HydrophobicContact CG-CD2 4.06Å; P144-Y414 HydrophobicContact CG-CE1 3.74Å; P144-Y414 HydrophobicContact CG-CE2 3.87Å; P144-Y414 HydrophobicContact CG-CG 4.12Å
145Q95.1Very high94.2Very high0 Ų026.3 Ų26.30%012%0.121CC..EExtended strand (participates in β ladder)trans-90109.7179.4-56-167-80.200110.1H143 M179 T181 S262 I388 V390 Y498H143-Q145 VanDerWaalsContact C-N 3.33Å; H143-Q145 PolarHBondContact ND1-N 2.69Å; H143-Q145 PolarHBondContact O-N 3.09Å; Q145-M179 HydrophobicContact CB-SD 4.42Å; Q145-T181 HydrophobicContact CG-CG2 4.11Å; Q145-T181 PolarHBondContact NE2-OG1 3.09Å; Q145-S262 PolarHBondContact O-N 2.99Å; Q145-I388 PolarHBondContact NE2-O 2.65Å; Q145-V390 HydrophobicContact CG-CB 4.4Å; Q145-V390 HydrophobicContact CG-CG2 4.37Å; Q145-Y498 PolarHBondContact OE1-OXT 3.28Å
146V95.5Very high94.2Very high3 Ų325.9 Ų25.92%0.01812%0.119CC..EExtended strand (participates in β ladder)trans-135.1163.7-166-63.70000111.4I148 I180 L182 L259 E260V146-I148 HydrophobicContact CG2-CG1 4.24Å; V146-I180 PolarHBondContact N-O 3.35Å; V146-I180 PolarHBondContact O-N 2.9Å; V146-L182 HydrophobicContact CG2-CD1 4.13Å; V146-L182 HydrophobicContact CG2-CG 3.98Å; V146-L259 HydrophobicContact CG2-CD2 4.21Å; V146-E260 CarbonylContact C-O 3.55Å; V146-E260 WeakPolarHBondContact CA-O 3.36Å; V146-E260 VanDerWaalsContact CB-O 3.26Å; V146-E260 WeakPolarHBondContact CB-O 3.4Å
147N97.5Very high94.3Very high5 Ų525.9 Ų25.93%0.02712%0.119CC..EExtended strand (participates in β ladder)trans-102.5143.6159.7-54.9121.4000108.7Y156 P173 S178 E260 S262N147-Y156 HydrophobicContact CB-CD1 4.17Å; N147-Y156 HydrophobicContact CB-CE1 4.31Å; N147-P173 HydrophobicContact CB-CB 3.71Å; N147-P173 HydrophobicContact CB-CG 4.4Å; N147-P173 VanDerWaalsContact CG-CB 3.43Å; N147-S178 PolarHBondContact ND2-O 2.82Å; N147-E260 HydrophobicContact CB-CB 4.48Å; N147-E260 PolarHBondContact N-O 2.76Å; N147-E260 PolarHBondContact O-N 3.48Å; N147-S262 WeakPolarHBondContact OD1-CA 3.41Å
148I97.8Very high94.5Very high1 Ų127 Ų271%0.00512%0.124CC..EExtended strand (participates in β ladder)trans-113119.1-178.1-55.7-177.2000108.6V146 Y156 A157 I180 L191 F226 M243 F257 L259V146-I148 HydrophobicContact CG2-CG1 4.24Å; I148-Y156 CarbonylContact O-C 3.53Å; I148-Y156 WeakPolarHBondContact O-CA 3.48Å; I148-A157 HydrophobicContact CB-CB 3.98Å; I148-A157 HydrophobicContact CG2-CB 4.49Å; I148-A157 PolarHBondContact O-N 2.88Å; I148-I180 HydrophobicContact CD1-CB 4.13Å; I148-I180 HydrophobicContact CD1-CG1 4.18Å; I148-I180 HydrophobicContact CD1-CG2 3.85Å; I148-I180 HydrophobicContact CG1-CB 4.36Å; I148-I180 HydrophobicContact CG1-CG1 4.37Å; I148-L191 HydrophobicContact CD1-CD2 3.87Å; I148-L191 HydrophobicContact CD1-CG 4.44Å; I148-F226 HydrophobicContact CD1-CZ 4.15Å; I148-M243 HydrophobicContact CG2-CE 4.1Å; I148-F257 HydrophobicContact CG2-CB 3.75Å; I148-F257 HydrophobicContact CG2-CD1 3.68Å; I148-F257 HydrophobicContact CG2-CG 3.88Å; I148-L259 HydrophobicContact CD1-CD2 4.43Å; I148-L259 HydrophobicContact CG1-CD2 3.91Å
149F98Very high94.8Very high45 Ų4527.1 Ų27.120%0.19712%0.124CC..EExtended strand (participates in β ladder)trans-108.3126178.5176.7-96.7000111K154 Y156 F257 V258F149-K154 HydrophobicContact CE2-CB 4.42Å; F149-K154 HydrophobicContact CZ-CB 3.94Å; F149-K154 HydrophobicContact CZ-CG 4.45Å; F149-Y156 HydrophobicContact CB-CD1 3.94Å; F149-Y156 HydrophobicContact CB-CE1 3.73Å; F149-Y156 HydrophobicContact CD2-CD1 4.21Å; F149-Y156 AromaticContact CD2-CD2 3.85Å; F149-Y156 HydrophobicContact CD2-CD2 3.85Å; F149-Y156 AromaticContact CD2-CE1 3.99Å; F149-Y156 HydrophobicContact CD2-CE1 3.99Å; F149-Y156 AromaticContact CD2-CE2 3.57Å; F149-Y156 HydrophobicContact CD2-CE2 3.57Å; F149-Y156 HydrophobicContact CD2-CG 4.17Å; F149-Y156 AromaticContact CD2-CZ 3.67Å; F149-Y156 HydrophobicContact CE2-CD2 4.46Å; F149-Y156 HydrophobicContact CE2-CE2 4.06Å; F149-Y156 HydrophobicContact CG-CE1 4.31Å; F149-F257 CarbonylContact O-C 3.58Å; F149-F257 WeakPolarHBondContact O-CA 3.24Å; F149-V258 HydrophobicContact CB-CB 4.2Å; F149-V258 HydrophobicContact CD1-CB 4.4Å; F149-V258 HydrophobicContact CD1-CG2 4.11Å; F149-V258 PolarHBondContact N-O 2.89Å; F149-V258 PolarHBondContact O-N 3.25Å
150S98.1Very high95Very high0 Ų027.8 Ų27.80%013%0.129CC..EExtended strand (participates in β ladder)trans-79.4126.8174.8171.80000111.2R153 K154 R155 P236S150-R153 PolarHBondContact OG-N 3.27Å; S150-K154 WeakPolarHBondContact O-CA 3.41Å; S150-K154 PolarHBondContact O-N 3.29Å; S150-R155 PolarHBondContact N-O 3.01Å; S150-P236 WeakPolarHBondContact OG-CG 3.48Å
151V95.8Very high94.7Very high47 Ų4734.2 Ų34.229%0.28516%0.163SC..THydrogen-bonded Turntrans-63.9-43.7178.3175.10000111.6K223 L256 V258V151-K223 HydrophobicContact CG2-CD 3.83Å; V151-K223 HydrophobicContact CG2-CG 4.35Å; V151-L256 HydrophobicContact CB-CB 4.3Å; V151-L256 WeakPolarHBondContact CB-O 3.39Å; V151-L256 HydrophobicContact CG2-CB 4Å; V151-L256 WeakPolarHBondContact CG2-O 3.49Å; V151-L256 PolarHBondContact N-O 3.26Å; V151-L256 VanDerWaalsContact N-O 3.11Å; V151-V258 HydrophobicContact CG2-CG2 4.36Å
152T96Very high94.7Very high62 Ų6243.7 Ų43.738%0.3820%0.204SC..THydrogen-bonded Turntrans-73.3-47.6-179.1-55.90000112.1K154 K253 D254T152-K154 VanDerWaalsContact C-N 3.31Å; T152-K154 PolarHBondContact O-N 2.97Å; T152-K253 PolarHBondContact OG1-O 2.88Å; T152-K253 VanDerWaalsContact OG1-O 3.07Å; T152-D254 VanDerWaalsContact CB-OD1 3.3Å; T152-D254 WeakPolarHBondContact CB-OD1 3.32Å; T152-D254 WeakPolarHBondContact CG2-OD1 3.21Å; T152-D254 VanDerWaalsContact OG1-CA 3.31Å; T152-D254 WeakPolarHBondContact OG1-CA 3.47Å; T152-D254 PolarHBondContact OG1-N 2.8Å; T152-D254 PolarHBondContact OG1-OD1 2.89Å
153R96.9Very high94.9Very high82 Ų8247.1 Ų47.131%0.30923%0.226SC..THydrogen-bonded Turntrans-73.7-25.2-176.3-67.6-69.9-177.4122.52.5112.7S150 R155 I168 P236 G238 P239S150-R153 PolarHBondContact OG-N 3.27Å; R153-R155 VanDerWaalsContact C-N 3.25Å; R153-R155 HydrophobicContact CB-CB 4.08Å; R153-R155 HydrophobicContact CB-CG 4.32Å; R153-R155 PolarHBondContact O-N 2.93Å; R153-I168 HydrophobicContact CB-CG2 4.32Å; R153-P236 HydrophobicContact CG-CB 3.73Å; R153-P236 HydrophobicContact CG-CG 3.76Å; R153-G238 PolarHBondContact NH1-O 2.95Å; R153-G238 VanDerWaalsContact NH1-O 3.12Å; R153-G238 PolarHBondContact NH2-O 2.87Å; R153-P239 PolarHBondContact NH1-O 3.12Å; R153-P239 VanDerWaalsContact NH1-O 3.15Å
154K97.8Very high95.2Very high143 Ų14350.7 Ų50.762%0.62225%0.245SC*.THydrogen-bonded Turntrans54.745.2-169.2-54-179.6-179.8-178.40111.4F149 S150 T152F149-K154 HydrophobicContact CE2-CB 4.42Å; F149-K154 HydrophobicContact CZ-CB 3.94Å; F149-K154 HydrophobicContact CZ-CG 4.45Å; S150-K154 WeakPolarHBondContact O-CA 3.41Å; S150-K154 PolarHBondContact O-N 3.29Å; T152-K154 VanDerWaalsContact C-N 3.31Å; T152-K154 PolarHBondContact O-N 2.97Å
155R98.3Very high95.4Very high89 Ų8951.4 Ų51.434%0.33625%0.248SC..EExtended strand (participates in β ladder)trans-143.4155.1-175.7-68-61.1-176.4-88.116.5109.8S150 R153 I168 D169 R170 D171S150-R155 PolarHBondContact N-O 3.01Å; R153-R155 VanDerWaalsContact C-N 3.25Å; R153-R155 HydrophobicContact CB-CB 4.08Å; R153-R155 HydrophobicContact CB-CG 4.32Å; R153-R155 PolarHBondContact O-N 2.93Å; R155-I168 HydrophobicContact CB-CG2 4.17Å; R155-I168 WeakPolarHBondContact CB-O 3.45Å; R155-I168 WeakPolarHBondContact O-CG2 3.3Å; R155-D169 WeakPolarHBondContact CD-O 3.21Å; R155-R170 CarbonylContact C-O 3.55Å; R155-R170 WeakPolarHBondContact CA-O 3.45Å; R155-R170 VanDerWaalsContact CD-O 3.25Å; R155-R170 WeakPolarHBondContact CD-O 3.4Å; R155-D171 IonicContact CZ-OD1 3.44Å; R155-D171 IonicContact NE-OD1 3.91Å; R155-D171 PolarHBondContact NE-OD1 3.47Å; R155-D171 IonicContact NH1-OD1 2.94Å; R155-D171 IonicContact NH2-OD1 2.76Å; R155-D171 PolarHBondContact NH2-OD1 2.77Å
156Y98.6Very high95.5Very high30 Ų3051.4 Ų51.412%0.11825%0.248CC..EExtended strand (participates in β ladder)trans-91.5144.7179-71.2-89.3000111.2N147 I148 F149 I168 R170 P173 E260N147-Y156 HydrophobicContact CB-CD1 4.17Å; N147-Y156 HydrophobicContact CB-CE1 4.31Å; I148-Y156 CarbonylContact O-C 3.53Å; I148-Y156 WeakPolarHBondContact O-CA 3.48Å; F149-Y156 HydrophobicContact CB-CD1 3.94Å; F149-Y156 HydrophobicContact CB-CE1 3.73Å; F149-Y156 HydrophobicContact CD2-CD1 4.21Å; F149-Y156 AromaticContact CD2-CD2 3.85Å; F149-Y156 HydrophobicContact CD2-CD2 3.85Å; F149-Y156 AromaticContact CD2-CE1 3.99Å; F149-Y156 HydrophobicContact CD2-CE1 3.99Å; F149-Y156 AromaticContact CD2-CE2 3.57Å; F149-Y156 HydrophobicContact CD2-CE2 3.57Å; F149-Y156 HydrophobicContact CD2-CG 4.17Å; F149-Y156 AromaticContact CD2-CZ 3.67Å; F149-Y156 HydrophobicContact CE2-CD2 4.46Å; F149-Y156 HydrophobicContact CE2-CE2 4.06Å; F149-Y156 HydrophobicContact CG-CE1 4.31Å; Y156-I168 WeakPolarHBondContact O-CA 3.33Å; Y156-R170 PolarHBondContact N-O 2.88Å; Y156-R170 PolarHBondContact O-N 3.21Å; Y156-P173 HydrophobicContact CD1-CB 3.67Å; Y156-P173 HydrophobicContact CD1-CG 4.02Å; Y156-P173 HydrophobicContact CD2-CG 4.5Å; Y156-P173 HydrophobicContact CE1-CB 3.92Å; Y156-P173 HydrophobicContact CE1-CG 3.74Å; Y156-P173 HydrophobicContact CE2-CG 4.29Å; Y156-P173 HydrophobicContact CG-CB 3.97Å; Y156-P173 HydrophobicContact CG-CG 4.36Å; Y156-E260 VanDerWaalsContact CE1-OE2 3.24Å; Y156-E260 WeakPolarHBondContact CE1-OE2 3.31Å; Y156-E260 PolarHBondContact OH-OE1 3.2Å; Y156-E260 PolarHBondContact OH-OE2 3.31Å
157A98.6Very high95.7Very high1 Ų151.2 Ų51.21%0.00825%0.248CC..EExtended strand (participates in β ladder)trans-71.5138.2168.900000110.1I148 I166 A167 I168I148-A157 HydrophobicContact CB-CB 3.98Å; I148-A157 HydrophobicContact CG2-CB 4.49Å; I148-A157 PolarHBondContact O-N 2.88Å; A157-I166 HydrophobicContact CB-CG2 3.84Å; A157-A167 CarbonylContact C-O 3.58Å; A157-A167 VanDerWaalsContact CA-O 3.23Å; A157-A167 WeakPolarHBondContact CA-O 3.39Å; A157-I168 HydrophobicContact CB-CG1 4.04Å
158H98.2Very high95.7Very high24 Ų2451 Ų5111%0.11125%0.247CC..EExtended strand (participates in β ladder)trans-151.4157.4172.779.1112.5000111.4S160 I166 A167 D169 D177H158-S160 PolarHBondContact O-N 2.8Å; H158-I166 CarbonylContact O-C 3.56Å; H158-I166 WeakPolarHBondContact O-CA 3.31Å; H158-A167 PolarHBondContact N-O 3.33Å; H158-A167 PolarHBondContact O-N 3.26Å; H158-D169 IonicContact CD2-OD1 2.74Å; H158-D169 IonicContact NE2-OD1 2.71Å; H158-D169 PolarHBondContact NE2-OD1 3.5Å; H158-D169 VanDerWaalsContact NE2-OD1 3.09Å; H158-D177 CarbonylContact C-O 3.48Å; H158-D177 WeakPolarHBondContact CA-O 3.28Å; H158-D177 WeakPolarHBondContact CB-O 3.29Å; H158-D177 IonicContact CE1-OD2 2.9Å; H158-D177 IonicContact CG-OD2 3.91Å; H158-D177 IonicContact ND1-OD2 2.92Å; H158-D177 PolarHBondContact ND1-OD2 3.26Å
159L97.8Very high95.7Very high9 Ų954.4 Ų54.45%0.04727%0.265CS..EExtended strand (participates in β ladder)trans-68.9122.8170.8175.364000109.7D177 T193 D195 L205L159-D177 HydrophobicContact CB-CB 4.05Å; L159-D177 PolarHBondContact N-O 3.37Å; L159-D177 WeakPolarHBondContact O-CB 3.35Å; L159-T193 HydrophobicContact CB-CG2 4.33Å; L159-T193 HydrophobicContact CD1-CG2 4.19Å; L159-D195 HydrophobicContact CD2-CB 3.93Å; L159-L205 HydrophobicContact CD1-CD1 3.39Å
160S95.8Very high95.6Very high14 Ų1453.7 Ų53.710%0.09826%0.26CS..EExtended strand (participates in β ladder)trans-107.1106178.5-179.80000111.2H158 K162 V163 D164 E165H158-S160 PolarHBondContact O-N 2.8Å; S160-K162 PolarHBondContact O-N 3.44Å; S160-V163 PolarHBondContact O-N 3.29Å; S160-D164 WeakPolarHBondContact O-CA 3.33Å; S160-D164 PolarHBondContact O-N 2.71Å; S160-E165 PolarHBondContact N-O 3.2Å
161D83.6Confident95.5Very high137 Ų13758.9 Ų58.973%0.73329%0.288SS*.THydrogen-bonded Turntrans-66-18.8177.4-63.3-25.4000113.2
162K85.6Confident95.6Very high201 Ų20159 Ų5987%0.87429%0.289SS*.THydrogen-bonded Turntrans-73.5-34.4-178.1-68-179.5-177.6172.50113S160S160-K162 PolarHBondContact O-N 3.44Å
163V86.1Confident95.6Very high90 Ų9056.9 Ų56.955%0.54528%0.276SS..THydrogen-bonded Turntrans-125.1-2.2-171-170.10000111.7S160 E165S160-V163 PolarHBondContact O-N 3.29Å; V163-E165 HydrophobicContact CB-CG 4.04Å; V163-E165 HydrophobicContact CG1-CG 4.22Å
164D94.7Very high95.6Very high82 Ų8253.2 Ų53.244%0.43926%0.263SS..THydrogen-bonded Turntrans58.349.3179.2-157.840.5000113.2S160 R197S160-D164 WeakPolarHBondContact O-CA 3.33Å; S160-D164 PolarHBondContact O-N 2.71Å; D164-R197 IonicContact OD1-CZ 2.97Å; D164-R197 IonicContact OD1-NH1 3.01Å; D164-R197 PolarHBondContact OD1-NH1 2.89Å; D164-R197 IonicContact OD1-NH2 3.49Å; D164-R197 PolarHBondContact OD1-NH2 3.04Å; D164-R197 IonicContact OD2-NH1 3.59Å; D164-R197 PolarHBondContact OD2-NH1 2.77Å
165E97.3Very high95.5Very high14 Ų1446.7 Ų46.77%0.06524%0.236CC..EExtended strand (participates in β ladder)trans-142170.2-174.868.6180-166.400112S160 V163 A167 S240 T242S160-E165 PolarHBondContact N-O 3.2Å; V163-E165 HydrophobicContact CB-CG 4.04Å; V163-E165 HydrophobicContact CG1-CG 4.22Å; E165-A167 HydrophobicContact CG-CB 4.4Å; E165-S240 WeakPolarHBondContact OE1-CB 3.43Å; E165-S240 PolarHBondContact OE1-OG 2.79Å; E165-T242 HydrophobicContact CB-CG2 4.3Å; E165-T242 VanDerWaalsContact CD-OG1 3.28Å; E165-T242 PolarHBondContact OE1-OG1 3.35Å; E165-T242 VanDerWaalsContact OE2-CB 3.28Å; E165-T242 WeakPolarHBondContact OE2-CB 3.35Å; E165-T242 WeakPolarHBondContact OE2-CG2 3.24Å; E165-T242 PolarHBondContact OE2-OG1 2.93Å
166I98.6Very high95.3Very high0 Ų045.1 Ų45.10%024%0.236CC..EExtended strand (participates in β ladder)trans-88106.9158.7-58.5-176.2000107.8A157 H158 I180 T193 L199 L205 M243A157-I166 HydrophobicContact CB-CG2 3.84Å; H158-I166 CarbonylContact O-C 3.56Å; H158-I166 WeakPolarHBondContact O-CA 3.31Å; I166-I180 HydrophobicContact CD1-CD1 4.16Å; I166-T193 HydrophobicContact CD1-CG2 3.64Å; I166-T193 HydrophobicContact CG1-CG2 3.7Å; I166-L199 HydrophobicContact CD1-CB 3.92Å; I166-L199 HydrophobicContact CD1-CD1 4.06Å; I166-L199 HydrophobicContact CD1-CD2 4.2Å; I166-L199 HydrophobicContact CD1-CG 4.27Å; I166-L199 HydrophobicContact CG1-CD1 4.24Å; I166-L205 HydrophobicContact CD1-CD2 4.31Å; I166-L205 HydrophobicContact CG1-CD2 4.03Å; I166-M243 HydrophobicContact CB-CB 4.04Å; I166-M243 HydrophobicContact CG2-CB 3.99Å; I166-M243 HydrophobicContact CG2-SD 4.1Å; I166-M243 PolarHBondContact O-N 3.4Å
167A98.4Very high95.1Very high0 Ų045.3 Ų45.30%024%0.239CC..EExtended strand (participates in β ladder)trans-88.9151.917500000110.3A157 H158 E165A157-A167 CarbonylContact C-O 3.58Å; A157-A167 VanDerWaalsContact CA-O 3.23Å; A157-A167 WeakPolarHBondContact CA-O 3.39Å; H158-A167 PolarHBondContact N-O 3.33Å; H158-A167 PolarHBondContact O-N 3.26Å; E165-A167 HydrophobicContact CG-CB 4.4Å
168I98.4Very high95Very high1 Ų145.3 Ų45.31%0.00524%0.239CC..EExtended strand (participates in β ladder)trans-126.160.1178.8-52.3168.9000109.5R153 R155 Y156 A157 P236 S240 G241 M243 F257R153-I168 HydrophobicContact CB-CG2 4.32Å; R155-I168 HydrophobicContact CB-CG2 4.17Å; R155-I168 WeakPolarHBondContact CB-O 3.45Å; R155-I168 WeakPolarHBondContact O-CG2 3.3Å; Y156-I168 WeakPolarHBondContact O-CA 3.33Å; A157-I168 HydrophobicContact CB-CG1 4.04Å; I168-P236 HydrophobicContact CB-CB 4.31Å; I168-P236 HydrophobicContact CD1-CB 3.89Å; I168-P236 HydrophobicContact CD1-CG 3.7Å; I168-P236 HydrophobicContact CG2-CG 4.5Å; I168-S240 CarbonylContact C-O 3.56Å; I168-S240 PolarHBondContact N-O 3.11Å; I168-G241 WeakPolarHBondContact CB-O 3.35Å; I168-G241 WeakPolarHBondContact CG1-O 3.41Å; I168-G241 PolarHBondContact N-O 2.9Å; I168-M243 HydrophobicContact CD1-CB 3.8Å; I168-M243 HydrophobicContact CD1-CE 4.21Å; I168-M243 HydrophobicContact CD1-CG 3.91Å; I168-M243 HydrophobicContact CD1-SD 4.37Å; I168-M243 HydrophobicContact CG1-CB 4.28Å; I168-F257 HydrophobicContact CD1-CE1 3.9Å
169D97.3Very high94.9Very high72 Ų7244.2 Ų44.239%0.38523%0.234SC..EExtended strand (participates in β ladder)trans-129.22.2-178.758.95000113.1R155 H158R155-D169 WeakPolarHBondContact CD-O 3.21Å; H158-D169 IonicContact CD2-OD1 2.74Å; H158-D169 IonicContact NE2-OD1 2.71Å; H158-D169 PolarHBondContact NE2-OD1 3.5Å; H158-D169 VanDerWaalsContact NE2-OD1 3.09Å
170R96.3Very high94.9Very high29 Ų2943.9 Ų43.911%0.10923%0.232CC..EExtended strand (participates in β ladder)trans-79.1132.9-178.6-157.2170.1-175.6176.1-2.8113.2R155 Y156 V172 W174 D177 S178 D293R155-R170 CarbonylContact C-O 3.55Å; R155-R170 WeakPolarHBondContact CA-O 3.45Å; R155-R170 VanDerWaalsContact CD-O 3.25Å; R155-R170 WeakPolarHBondContact CD-O 3.4Å; Y156-R170 PolarHBondContact N-O 2.88Å; Y156-R170 PolarHBondContact O-N 3.21Å; R170-V172 WeakPolarHBondContact CD-O 3.16Å; R170-V172 VanDerWaalsContact CG-O 3.31Å; R170-V172 WeakPolarHBondContact CG-O 3.28Å; R170-V172 PolarHBondContact NE-O 3.48Å; R170-W174 PolarHBondContact NH1-O 3.16Å; R170-W174 VanDerWaalsContact NH2-C 3.28Å; R170-W174 PolarHBondContact NH2-O 2.92Å; R170-D177 IonicContact CZ-OD1 3.68Å; R170-D177 IonicContact CZ-OD2 3.91Å; R170-D177 IonicContact NH1-OD1 3.09Å; R170-D177 PolarHBondContact NH1-OD1 3.48Å; R170-D177 IonicContact NH1-OD2 3.63Å; R170-D177 PolarHBondContact NH1-OD2 3.45Å; R170-D177 IonicContact NH2-OD1 3.56Å; R170-S178 PolarHBondContact NH1-OG 2.83Å; R170-D293 IonicContact CZ-OD2 3.92Å; R170-D293 VanDerWaalsContact NH2-CG 3.3Å; R170-D293 IonicContact NH2-OD1 3.5Å; R170-D293 PolarHBondContact NH2-OD1 3.18Å; R170-D293 IonicContact NH2-OD2 2.71Å; R170-D293 PolarHBondContact NH2-OD2 2.75Å
171D96.6Very high94.9Very high109 Ų10943.2 Ų43.258%0.58323%0.227SC*.SBendtrans-70.9-36.9-176.5-69-43.2000112.9R155R155-D171 IonicContact CZ-OD1 3.44Å; R155-D171 IonicContact NE-OD1 3.91Å; R155-D171 PolarHBondContact NE-OD1 3.47Å; R155-D171 IonicContact NH1-OD1 2.94Å; R155-D171 IonicContact NH2-OD1 2.76Å; R155-D171 PolarHBondContact NH2-OD1 2.77Å
172V96.7Very high95.5Very high50 Ų5036.7 Ų36.730%0.30319%0.192SC..SBendtrans-138.8149.7-177.2-68.10000110.4R170 W174R170-V172 WeakPolarHBondContact CD-O 3.16Å; R170-V172 VanDerWaalsContact CG-O 3.31Å; R170-V172 WeakPolarHBondContact CG-O 3.28Å; R170-V172 PolarHBondContact NE-O 3.48Å; V172-W174 HydrophobicContact CG2-CB 4.19Å; V172-W174 PolarHBondContact O-N 2.92Å
173P96.8Very high95.9Very high17 Ų1727.3 Ų27.311%0.1115%0.152CC..  trans-8362.4-175.934.2-33.3000111.6N147 Y156 S178 Q265N147-P173 HydrophobicContact CB-CB 3.71Å; N147-P173 HydrophobicContact CB-CG 4.4Å; N147-P173 VanDerWaalsContact CG-CB 3.43Å; Y156-P173 HydrophobicContact CD1-CB 3.67Å; Y156-P173 HydrophobicContact CD1-CG 4.02Å; Y156-P173 HydrophobicContact CD2-CG 4.5Å; Y156-P173 HydrophobicContact CE1-CB 3.92Å; Y156-P173 HydrophobicContact CE1-CG 3.74Å; Y156-P173 HydrophobicContact CE2-CG 4.29Å; Y156-P173 HydrophobicContact CG-CB 3.97Å; Y156-P173 HydrophobicContact CG-CG 4.36Å; P173-S178 VanDerWaalsContact C-CB 3.48Å; P173-S178 VanDerWaalsContact C-OG 3.31Å; P173-S178 WeakPolarHBondContact CA-OG 3.35Å; P173-Q265 PolarHBondContact O-NE2 2.92Å
174W96.8Very high96.2Very high6 Ų624.5 Ų24.52%0.02313%0.132CC..  trans-96.3165.8-176.6-136.6-109.5000112.5R170 V172 S178 D293 V296 Q298 R311 T312 A313R170-W174 PolarHBondContact NH1-O 3.16Å; R170-W174 VanDerWaalsContact NH2-C 3.28Å; R170-W174 PolarHBondContact NH2-O 2.92Å; V172-W174 HydrophobicContact CG2-CB 4.19Å; V172-W174 PolarHBondContact O-N 2.92Å; W174-S178 PolarHBondContact N-OG 3.44Å; W174-S178 WeakPolarHBondContact O-CB 3.31Å; W174-S178 PolarHBondContact O-OG 3.42Å; W174-D293 PolarHBondContact NE1-O 2.98Å; W174-V296 WeakPolarHBondContact CZ2-O 3.38Å; W174-V296 PolarHBondContact NE1-O 2.84Å; W174-Q298 HydrophobicContact CH2-CB 3.31Å; W174-Q298 HydrophobicContact CZ2-CB 4.04Å; W174-Q298 HydrophobicContact CZ3-CB 3.77Å; W174-R311 HydrophobicContact CH2-CB 4.21Å; W174-R311 HydrophobicContact CH2-CG 4.18Å; W174-R311 WeakPolarHBondContact CH2-O 3.41Å; W174-R311 WeakPolarHBondContact CZ2-O 3.2Å; W174-T312 WeakPolarHBondContact CH2-O 3.22Å; W174-A313 HydrophobicContact CB-CB 4.41Å; W174-A313 HydrophobicContact CD2-CB 3.9Å; W174-A313 HydrophobicContact CG-CB 3.75Å; W174-A313 VanDerWaalsContact CZ2-N 3.29Å
175G94.7Very high95.9Very high6 Ų624.5 Ų24.56%0.06213%0.126CC..THydrogen-bonded Turntrans66.7177.717600000115.5D177G175-D177 VanDerWaalsContact C-N 3.34Å
176V94.3Very high95.4Very high55 Ų5531.8 Ų31.833%0.33316%0.16SC..G310 helixtrans-70.5-30.7-177.261.80000113S178 M179 S194 I384 P387V176-S178 VanDerWaalsContact C-N 3.35Å; V176-S178 PolarHBondContact O-N 2.56Å; V176-M179 PolarHBondContact O-N 2.93Å; V176-S194 WeakPolarHBondContact O-CB 3.03Å; V176-S194 PolarHBondContact O-OG 3.43Å; V176-I384 WeakPolarHBondContact CG2-O 3.13Å; V176-P387 HydrophobicContact CG2-CG 3.65Å
177D95.5Very high94.8Very high35 Ų3533.5 Ų33.519%0.18717%0.169CC..G310 helixtrans-76-18.2-175.759.9-47.2000113.7H158 L159 R170 G175 M179H158-D177 CarbonylContact C-O 3.48Å; H158-D177 WeakPolarHBondContact CA-O 3.28Å; H158-D177 WeakPolarHBondContact CB-O 3.29Å; H158-D177 IonicContact CE1-OD2 2.9Å; H158-D177 IonicContact CG-OD2 3.91Å; H158-D177 IonicContact ND1-OD2 2.92Å; H158-D177 PolarHBondContact ND1-OD2 3.26Å; L159-D177 HydrophobicContact CB-CB 4.05Å; L159-D177 PolarHBondContact N-O 3.37Å; L159-D177 WeakPolarHBondContact O-CB 3.35Å; R170-D177 IonicContact CZ-OD1 3.68Å; R170-D177 IonicContact CZ-OD2 3.91Å; R170-D177 IonicContact NH1-OD1 3.09Å; R170-D177 PolarHBondContact NH1-OD1 3.48Å; R170-D177 IonicContact NH1-OD2 3.63Å; R170-D177 PolarHBondContact NH1-OD2 3.45Å; R170-D177 IonicContact NH2-OD1 3.56Å; G175-D177 VanDerWaalsContact C-N 3.34Å; D177-M179 VanDerWaalsContact C-N 3.3Å
178S96.8Very high94.5Very high1 Ų135 Ų351%0.00717%0.174CC..G310 helixtrans-78.9-10.5175-67.20000114.2N147 R170 P173 W174 V176N147-S178 PolarHBondContact ND2-O 2.82Å; R170-S178 PolarHBondContact NH1-OG 2.83Å; P173-S178 VanDerWaalsContact C-CB 3.48Å; P173-S178 VanDerWaalsContact C-OG 3.31Å; P173-S178 WeakPolarHBondContact CA-OG 3.35Å; W174-S178 PolarHBondContact N-OG 3.44Å; W174-S178 WeakPolarHBondContact O-CB 3.31Å; W174-S178 PolarHBondContact O-OG 3.42Å; V176-S178 VanDerWaalsContact C-N 3.35Å; V176-S178 PolarHBondContact O-N 2.56Å
179M95.5Very high94.3Very high1 Ų135.1 Ų35.11%0.00518%0.175CC..  trans-83.2123.9-177.6-173.2-78.4-68.300110.3Q145 V176 D177 T181 P387 I388Q145-M179 HydrophobicContact CB-SD 4.42Å; V176-M179 PolarHBondContact O-N 2.93Å; D177-M179 VanDerWaalsContact C-N 3.3Å; M179-T181 PolarHBondContact SD-OG1 2.79Å; M179-P387 HydrophobicContact CE-CG 4.37Å; M179-I388 HydrophobicContact CE-CD1 4.23Å; M179-I388 HydrophobicContact CE-CG1 3.67Å
180I97.4Very high94.3Very high1 Ų132 Ų321%0.00516%0.157CC..EExtended strand (participates in β ladder)trans-116.1129.5171.3-58-62.5000108.7V146 I148 I166 L191 Q192 T193V146-I180 PolarHBondContact N-O 3.35Å; V146-I180 PolarHBondContact O-N 2.9Å; I148-I180 HydrophobicContact CD1-CB 4.13Å; I148-I180 HydrophobicContact CD1-CG1 4.18Å; I148-I180 HydrophobicContact CD1-CG2 3.85Å; I148-I180 HydrophobicContact CG1-CB 4.36Å; I148-I180 HydrophobicContact CG1-CG1 4.37Å; I166-I180 HydrophobicContact CD1-CD1 4.16Å; I180-L191 HydrophobicContact CG2-CB 4.13Å; I180-L191 HydrophobicContact CG2-CG 4.24Å; I180-Q192 WeakPolarHBondContact CA-O 3.42Å; I180-T193 HydrophobicContact CD1-CG2 4.08Å
181T96.3Very high94.4Very high0 Ų030.6 Ų30.60%015%0.152CC..EExtended strand (participates in β ladder)trans-99.5118.8171.9-58.10000109.3Q145 M179 V183 Q192 V390Q145-T181 HydrophobicContact CG-CG2 4.11Å; Q145-T181 PolarHBondContact NE2-OG1 3.09Å; M179-T181 PolarHBondContact SD-OG1 2.79Å; T181-V183 HydrophobicContact CG2-CG2 3.94Å; T181-V183 PolarHBondContact O-N 2.95Å; T181-Q192 PolarHBondContact N-O 3.28Å; T181-Q192 WeakPolarHBondContact O-CB 3.42Å; T181-Q192 PolarHBondContact O-N 3.36Å; T181-V390 HydrophobicContact CG2-CG2 4.44Å
182L95.8Very high94.4Very high0 Ų025.4 Ų25.40%012%0.124CC..EExtended strand (participates in β ladder)trans-77.9108.9171.5-61.7-178.9000108.4I140 P144 V146 Y189 L191 F226 L259 Y414I140-L182 HydrophobicContact CD1-CB 4.41Å; I140-L182 HydrophobicContact CD1-CD1 3.83Å; P144-L182 HydrophobicContact CB-CB 4.36Å; P144-L182 VanDerWaalsContact CB-O 3.23Å; P144-L182 WeakPolarHBondContact CB-O 3.34Å; P144-L182 PolarHBondContact O-N 3.41Å; V146-L182 HydrophobicContact CG2-CD1 4.13Å; V146-L182 HydrophobicContact CG2-CG 3.98Å; L182-Y189 HydrophobicContact CB-CD1 3.88Å; L182-Y189 HydrophobicContact CB-CE1 4.32Å; L182-L191 HydrophobicContact CD2-CD1 4.23Å; L182-L191 HydrophobicContact CD2-CG 4.09Å; L182-F226 HydrophobicContact CD2-CE1 4.2Å; L182-L259 HydrophobicContact CD1-CD1 3.93Å; L182-Y414 PolarHBondContact O-OH 2.9Å
183V94.3Very high94.4Very high4 Ų423 Ų232%0.02411%0.11CC..EExtended strand (participates in β ladder)trans-100.6119.1-177.7176.80000110.4T181 R185 Y189 H190 Q192 F198 Y416T181-V183 HydrophobicContact CG2-CG2 3.94Å; T181-V183 PolarHBondContact O-N 2.95Å; V183-R185 HydrophobicContact CG1-CG 3.96Å; V183-Y189 CarbonylContact O-C 3.5Å; V183-Y189 WeakPolarHBondContact O-CA 3.46Å; V183-H190 HydrophobicContact CB-CB 4.41Å; V183-H190 PolarHBondContact N-O 2.93Å; V183-H190 PolarHBondContact O-CD2 3.11Å; V183-H190 PolarHBondContact O-N 3.4Å; V183-Q192 HydrophobicContact CG2-CB 3.94Å; V183-Q192 VanDerWaalsContact CG2-OE1 3.3Å; V183-F198 HydrophobicContact CB-CE1 4.22Å; V183-F198 HydrophobicContact CG1-CE1 4.48Å; V183-F198 HydrophobicContact CG2-CE1 4.12Å; V183-Y416 HydrophobicContact CG1-CE1 4.41Å; V183-Y416 HydrophobicContact CG2-CD1 4.42Å; V183-Y416 HydrophobicContact CG2-CE1 4.26Å
184F91.6Very high94.3Very high31 Ų3122.9 Ų22.914%0.13611%0.109CC..EExtended strand (participates in β ladder)trans-86.9113.2177.7-168.6-108.6000112.1I21 V138 H139 Q187 R188 Y189 Y414I21-F184 HydrophobicContact CD1-CE1 4.1Å; I21-F184 HydrophobicContact CD1-CZ 4.16Å; V138-F184 WeakPolarHBondContact O-CE2 3.38Å; H139-F184 HydrophobicContact CB-CE1 4.47Å; H139-F184 HydrophobicContact CB-CZ 4.25Å; H139-F184 AromaticContact CD2-CD1 3.45Å; H139-F184 VanDerWaalsContact CD2-CD1 3.45Å; H139-F184 WeakPolarHBondContact CD2-CD1 3.23Å; H139-F184 AromaticContact CD2-CD2 3.99Å; H139-F184 AromaticContact CD2-CE1 3.73Å; H139-F184 AromaticContact CD2-CG 3.55Å; H139-F184 AromaticContact NE2-CD1 3.69Å; H139-F184 AromaticContact NE2-CG 3.98Å; F184-Q187 HydrophobicContact CZ-CB 4.47Å; F184-R188 CarbonylContact C-O 3.34Å; F184-R188 WeakPolarHBondContact CA-O 3.42Å; F184-R188 WeakPolarHBondContact CD2-O 3.37Å; F184-Y189 HydrophobicContact CB-CD1 4.34Å; F184-Y189 HydrophobicContact CB-CE1 3.86Å; F184-Y189 HydrophobicContact CD2-CD1 4.28Å; F184-Y189 AromaticContact CD2-CD2 3.94Å; F184-Y189 HydrophobicContact CD2-CD2 3.94Å; F184-Y189 AromaticContact CD2-CE1 3.87Å; F184-Y189 HydrophobicContact CD2-CE1 3.87Å; F184-Y189 AromaticContact CD2-CE2 3.51Å; F184-Y189 HydrophobicContact CD2-CE2 3.51Å; F184-Y189 HydrophobicContact CD2-CG 4.31Å; F184-Y189 AromaticContact CD2-CZ 3.44Å; F184-Y189 VanDerWaalsContact CD2-CZ 3.44Å; F184-Y189 HydrophobicContact CE2-CD2 4.37Å; F184-Y189 AromaticContact CE2-CE2 3.85Å; F184-Y189 HydrophobicContact CE2-CE2 3.85Å; F184-Y189 HydrophobicContact CG-CE1 4.32Å; F184-Y414 PolarHBondContact N-OH 2.92Å; F184-Y414 VanDerWaalsContact N-OH 3.14Å
185R89.2Confident94.1Very high82 Ų8225.3 Ų25.331%0.30912%0.123SC..EExtended strand (participates in β ladder)trans-142.5143.5177.6-72.3176.2-176.8172.44.3110.2V183 Q187 R188 Y416V183-R185 HydrophobicContact CG1-CG 3.96Å; R185-Q187 PolarHBondContact O-N 2.78Å; R185-R188 PolarHBondContact N-O 2.9Å; R185-R188 PolarHBondContact O-N 2.9Å; R185-R188 VanDerWaalsContact O-O 3.06Å; R185-Y416 PolarHBondContact NH2-OH 3.45Å
186E86.4Confident94Very high167 Ų16727.9 Ų27.978%0.7814%0.135SC*.THydrogen-bonded Turntrans48.737.7177.7-57.4-173.6172.400113.5R188E186-R188 VanDerWaalsContact C-N 3.28Å; E186-R188 PolarHBondContact O-N 2.84Å
187Q85.6Confident94.1Very high37 Ų3727.6 Ų27.617%0.17313%0.128CC..THydrogen-bonded Turntrans6523.3-178-51.2-63.86.800115.3N25 S137 F184 R185N25-Q187 PolarHBondContact OD1-NE2 3.22Å; S137-Q187 VanDerWaalsContact CB-OE1 3.22Å; S137-Q187 WeakPolarHBondContact OG-CB 3.26Å; S137-Q187 WeakPolarHBondContact OG-CG 3.42Å; S137-Q187 PolarHBondContact OG-OE1 3.18Å; F184-Q187 HydrophobicContact CZ-CB 4.47Å; R185-Q187 PolarHBondContact O-N 2.78Å
188R91.9Very high94.2Very high31 Ų3126.1 Ų26.112%0.11712%0.12CC..EExtended strand (participates in β ladder)trans-133.4164.2176.5-64.1-174.4-178.5-149.90.7111.4D101 D102 F184 R185 E186 G214D101-R188 PolarHBondContact O-NH2 2.66Å; D102-R188 PolarHBondContact O-NE 2.92Å; D102-R188 PolarHBondContact O-NH2 3.11Å; D102-R188 VanDerWaalsContact O-NH2 3.09Å; F184-R188 CarbonylContact C-O 3.34Å; F184-R188 WeakPolarHBondContact CA-O 3.42Å; F184-R188 WeakPolarHBondContact CD2-O 3.37Å; R185-R188 PolarHBondContact N-O 2.9Å; R185-R188 PolarHBondContact O-N 2.9Å; R185-R188 VanDerWaalsContact O-O 3.06Å; E186-R188 VanDerWaalsContact C-N 3.28Å; E186-R188 PolarHBondContact O-N 2.84Å; R188-G214 PolarHBondContact NH1-O 3.23Å
189Y95.1Very high94.3Very high4 Ų426 Ų262%0.01612%0.12CC..EExtended strand (participates in β ladder)trans-100.9136.5172.1-77.7-80.8000111.5V138 H139 I140 L182 V183 F184 Y215 L217V138-Y189 WeakPolarHBondContact O-CE2 3.36Å; H139-Y189 WeakPolarHBondContact CA-OH 3.5Å; H139-Y189 PolarHBondContact CD2-OH 3.02Å; I140-Y189 HydrophobicContact CD1-CE1 3.81Å; I140-Y189 HydrophobicContact CG1-CE1 4.06Å; I140-Y189 WeakPolarHBondContact CG1-OH 3.24Å; I140-Y189 HydrophobicContact CG2-CE2 4.23Å; I140-Y189 PolarHBondContact N-OH 2.84Å; L182-Y189 HydrophobicContact CB-CD1 3.88Å; L182-Y189 HydrophobicContact CB-CE1 4.32Å; V183-Y189 CarbonylContact O-C 3.5Å; V183-Y189 WeakPolarHBondContact O-CA 3.46Å; F184-Y189 HydrophobicContact CB-CD1 4.34Å; F184-Y189 HydrophobicContact CB-CE1 3.86Å; F184-Y189 HydrophobicContact CD2-CD1 4.28Å; F184-Y189 AromaticContact CD2-CD2 3.94Å; F184-Y189 HydrophobicContact CD2-CD2 3.94Å; F184-Y189 AromaticContact CD2-CE1 3.87Å; F184-Y189 HydrophobicContact CD2-CE1 3.87Å; F184-Y189 AromaticContact CD2-CE2 3.51Å; F184-Y189 HydrophobicContact CD2-CE2 3.51Å; F184-Y189 HydrophobicContact CD2-CG 4.31Å; F184-Y189 AromaticContact CD2-CZ 3.44Å; F184-Y189 VanDerWaalsContact CD2-CZ 3.44Å; F184-Y189 HydrophobicContact CE2-CD2 4.37Å; F184-Y189 AromaticContact CE2-CE2 3.85Å; F184-Y189 HydrophobicContact CE2-CE2 3.85Å; F184-Y189 HydrophobicContact CG-CE1 4.32Å; Y189-Y215 PolarHBondContact N-O 2.86Å; Y189-Y215 WeakPolarHBondContact O-CD2 3.32Å; Y189-Y215 PolarHBondContact O-N 2.93Å; Y189-L217 HydrophobicContact CD2-CD1 3.53Å; Y189-L217 HydrophobicContact CD2-CD2 4.17Å; Y189-L217 HydrophobicContact CD2-CG 3.55Å; Y189-L217 HydrophobicContact CE2-CD1 3.61Å; Y189-L217 HydrophobicContact CE2-CG 4.07Å; Y189-L217 HydrophobicContact CG-CD1 4.09Å; Y189-L217 HydrophobicContact CG-CD2 4.3Å; Y189-L217 HydrophobicContact CG-CG 4.15Å
190H96.9Very high94.5Very high5 Ų529.7 Ų29.72%0.02313%0.134CC..EExtended strand (participates in β ladder)trans-114.3135.4172.4-55.7-99.5000108.2V183 Q192 F198 T209 T213V183-H190 HydrophobicContact CB-CB 4.41Å; V183-H190 PolarHBondContact N-O 2.93Å; V183-H190 PolarHBondContact O-CD2 3.11Å; V183-H190 PolarHBondContact O-N 3.4Å; H190-Q192 PolarHBondContact O-N 2.98Å; H190-F198 HydrophobicContact CB-CD1 3.66Å; H190-F198 HydrophobicContact CB-CE1 4.12Å; H190-T209 HydrophobicContact CB-CG2 4.15Å; H190-T213 PolarHBondContact CE1-OG1 2.96Å; H190-T213 PolarHBondContact ND1-O 2.84Å; H190-T213 PolarHBondContact ND1-OG1 3.43Å
191L98Very high94.5Very high0 Ų031.1 Ų31.10%014%0.141CC..EExtended strand (participates in β ladder)trans-89107.6177.3-78.166.4000107.6I148 I180 L182 F198 L199 Y215 F226 L234 M243I148-L191 HydrophobicContact CD1-CD2 3.87Å; I148-L191 HydrophobicContact CD1-CG 4.44Å; I180-L191 HydrophobicContact CG2-CB 4.13Å; I180-L191 HydrophobicContact CG2-CG 4.24Å; L182-L191 HydrophobicContact CD2-CD1 4.23Å; L182-L191 HydrophobicContact CD2-CG 4.09Å; L191-F198 WeakPolarHBondContact O-CA 3.29Å; L191-L199 HydrophobicContact CB-CB 4.06Å; L191-L199 HydrophobicContact CD2-CD2 4.11Å; L191-L199 PolarHBondContact O-N 3.4Å; L191-Y215 HydrophobicContact CD1-CD2 3.72Å; L191-Y215 HydrophobicContact CD1-CE2 4.13Å; L191-Y215 HydrophobicContact CD1-CG 4.45Å; L191-F226 HydrophobicContact CD1-CD1 3.81Å; L191-F226 HydrophobicContact CD1-CE1 3.82Å; L191-F226 HydrophobicContact CD2-CE1 4.44Å; L191-F226 HydrophobicContact CD2-CZ 4.45Å; L191-F226 HydrophobicContact CG-CE1 4.45Å; L191-L234 HydrophobicContact CD2-CD1 4.05Å; L191-M243 HydrophobicContact CD2-CE 4.24Å; L191-M243 HydrophobicContact CD2-SD 3.84Å
192Q97.2Very high94.5Very high0 Ų035 Ų350%016%0.162CC..EExtended strand (participates in β ladder)trans-98.7128.8179.3-163.8-17716.700110.6I180 T181 V183 H190 N196 R197 F198I180-Q192 WeakPolarHBondContact CA-O 3.42Å; T181-Q192 PolarHBondContact N-O 3.28Å; T181-Q192 WeakPolarHBondContact O-CB 3.42Å; T181-Q192 PolarHBondContact O-N 3.36Å; V183-Q192 HydrophobicContact CG2-CB 3.94Å; V183-Q192 VanDerWaalsContact CG2-OE1 3.3Å; H190-Q192 PolarHBondContact O-N 2.98Å; Q192-N196 PolarHBondContact NE2-O 2.84Å; Q192-N196 PolarHBondContact NE2-OD1 2.86Å; Q192-R197 CarbonylContact C-O 3.59Å; Q192-R197 VanDerWaalsContact CA-O 3.25Å; Q192-R197 WeakPolarHBondContact CA-O 3.37Å; Q192-R197 WeakPolarHBondContact CG-O 3.44Å; Q192-F198 HydrophobicContact CB-CD1 3.84Å; Q192-F198 HydrophobicContact CB-CE1 3.66Å; Q192-F198 HydrophobicContact CB-CZ 4.45Å; Q192-F198 HydrophobicContact CG-CD1 4Å; Q192-F198 HydrophobicContact CG-CE1 3.64Å; Q192-F198 HydrophobicContact CG-CZ 3.94Å
193T96.8Very high94.6Very high0 Ų035.3 Ų35.30%017%0.165CC..  trans-82.4167.5174.844.90000111.5L159 I166 I180 D195 N196 R197 L205L159-T193 HydrophobicContact CB-CG2 4.33Å; L159-T193 HydrophobicContact CD1-CG2 4.19Å; I166-T193 HydrophobicContact CD1-CG2 3.64Å; I166-T193 HydrophobicContact CG1-CG2 3.7Å; I180-T193 HydrophobicContact CD1-CG2 4.08Å; T193-D195 WeakPolarHBondContact CB-OD1 3.28Å; T193-D195 PolarHBondContact O-N 2.59Å; T193-D195 VanDerWaalsContact O-N 3.14Å; T193-D195 PolarHBondContact OG1-OD1 2.72Å; T193-N196 PolarHBondContact O-N 3.35Å; T193-R197 PolarHBondContact N-O 2.9Å; T193-R197 PolarHBondContact OG1-O 2.96Å; T193-R197 VanDerWaalsContact OG1-O 3.09Å; T193-L205 HydrophobicContact CG2-CD2 3.93Å
194S93.4Very high94.8Very high14 Ų1436.6 Ų36.610%0.09818%0.176CC..THydrogen-bonded Turntrans-62.7-17.4-177.953.70000114.8V176 P387V176-S194 WeakPolarHBondContact O-CB 3.03Å; V176-S194 PolarHBondContact O-OG 3.43Å; S194-P387 WeakPolarHBondContact O-CG 3.42Å
195D93.4Very high95.1Very high58 Ų5835.9 Ų35.931%0.3117%0.174SC..THydrogen-bonded Turntrans-95.115.7175.470.6-8.6000113.7L159 T193 R197L159-D195 HydrophobicContact CD2-CB 3.93Å; T193-D195 WeakPolarHBondContact CB-OD1 3.28Å; T193-D195 PolarHBondContact O-N 2.59Å; T193-D195 VanDerWaalsContact O-N 3.14Å; T193-D195 PolarHBondContact OG1-OD1 2.72Å; D195-R197 VanDerWaalsContact C-N 3.31Å; D195-R197 PolarHBondContact O-N 3.22Å; D195-R197 PolarHBondContact OD1-N 2.81Å; D195-R197 IonicContact OD1-NE 2.56Å; D195-R197 IonicContact OD2-CZ 3.7Å; D195-R197 IonicContact OD2-NE 2.84Å; D195-R197 PolarHBondContact OD2-NE 3.36Å; D195-R197 IonicContact OD2-NH2 3.63Å; D195-R197 PolarHBondContact OD2-NH2 3.49Å
196N92.8Very high95.5Very high59 Ų5933.5 Ų33.532%0.31617%0.168SC..SBendtrans70.87178.8-67.7-69.6000117.3Q192 T193 I388Q192-N196 PolarHBondContact NE2-O 2.84Å; Q192-N196 PolarHBondContact NE2-OD1 2.86Å; T193-N196 PolarHBondContact O-N 3.35Å; N196-I388 VanDerWaalsContact OD1-CG2 3.26Å; N196-I388 WeakPolarHBondContact OD1-CG2 3.4Å
197R96.1Very high95.9Very high49 Ų4929.3 Ų29.319%0.18516%0.162CC..  trans-86161.2174.2-64.1-176.4-66.4166.4-3.7112.1D164 Q192 T193 D195 L205 V206D164-R197 IonicContact OD1-CZ 2.97Å; D164-R197 IonicContact OD1-NH1 3.01Å; D164-R197 PolarHBondContact OD1-NH1 2.89Å; D164-R197 IonicContact OD1-NH2 3.49Å; D164-R197 PolarHBondContact OD1-NH2 3.04Å; D164-R197 IonicContact OD2-NH1 3.59Å; D164-R197 PolarHBondContact OD2-NH1 2.77Å; Q192-R197 CarbonylContact C-O 3.59Å; Q192-R197 VanDerWaalsContact CA-O 3.25Å; Q192-R197 WeakPolarHBondContact CA-O 3.37Å; Q192-R197 WeakPolarHBondContact CG-O 3.44Å; T193-R197 PolarHBondContact N-O 2.9Å; T193-R197 PolarHBondContact OG1-O 2.96Å; T193-R197 VanDerWaalsContact OG1-O 3.09Å; D195-R197 VanDerWaalsContact C-N 3.31Å; D195-R197 PolarHBondContact O-N 3.22Å; D195-R197 PolarHBondContact OD1-N 2.81Å; D195-R197 IonicContact OD1-NE 2.56Å; D195-R197 IonicContact OD2-CZ 3.7Å; D195-R197 IonicContact OD2-NE 2.84Å; D195-R197 PolarHBondContact OD2-NE 3.36Å; D195-R197 IonicContact OD2-NH2 3.63Å; D195-R197 PolarHBondContact OD2-NH2 3.49Å; R197-L205 HydrophobicContact CB-CB 4.02Å; R197-V206 CarbonylContact C-O 3.57Å; R197-V206 WeakPolarHBondContact CA-O 3.38Å
198F98.2Very high96.4Very high4 Ų432.4 Ų32.42%0.01818%0.184CC..EExtended strand (participates in β ladder)trans-113.8138.5-178.6-60.9-83.4000110.7V183 H190 L191 Q192 R200 L205 V206 T209 T213V183-F198 HydrophobicContact CB-CE1 4.22Å; V183-F198 HydrophobicContact CG1-CE1 4.48Å; V183-F198 HydrophobicContact CG2-CE1 4.12Å; H190-F198 HydrophobicContact CB-CD1 3.66Å; H190-F198 HydrophobicContact CB-CE1 4.12Å; L191-F198 WeakPolarHBondContact O-CA 3.29Å; Q192-F198 HydrophobicContact CB-CD1 3.84Å; Q192-F198 HydrophobicContact CB-CE1 3.66Å; Q192-F198 HydrophobicContact CB-CZ 4.45Å; Q192-F198 HydrophobicContact CG-CD1 4Å; Q192-F198 HydrophobicContact CG-CE1 3.64Å; Q192-F198 HydrophobicContact CG-CZ 3.94Å; F198-R200 PolarHBondContact O-N 3.32Å; F198-L205 WeakPolarHBondContact O-CA 3.36Å; F198-V206 PolarHBondContact N-O 2.77Å; F198-V206 PolarHBondContact O-N 2.85Å; F198-T209 HydrophobicContact CD1-CG2 3.7Å; F198-T209 HydrophobicContact CD2-CG2 3.74Å; F198-T209 HydrophobicContact CE1-CG2 3.7Å; F198-T209 HydrophobicContact CE2-CG2 3.78Å; F198-T209 HydrophobicContact CG-CG2 3.7Å; F198-T209 HydrophobicContact CZ-CG2 3.76Å; F198-T213 HydrophobicContact CB-CG2 4.26Å
199L98.7Very high96.6Very high0 Ų033 Ų330%019%0.19CC..EExtended strand (participates in β ladder)trans-67.8125172.7-175.466.8000110.7I166 L191 T213 Y215 L234 M243I166-L199 HydrophobicContact CD1-CB 3.92Å; I166-L199 HydrophobicContact CD1-CD1 4.06Å; I166-L199 HydrophobicContact CD1-CD2 4.2Å; I166-L199 HydrophobicContact CD1-CG 4.27Å; I166-L199 HydrophobicContact CG1-CD1 4.24Å; L191-L199 HydrophobicContact CB-CB 4.06Å; L191-L199 HydrophobicContact CD2-CD2 4.11Å; L191-L199 PolarHBondContact O-N 3.4Å; L199-T213 VanDerWaalsContact O-CA 3.3Å; L199-T213 WeakPolarHBondContact O-CA 3.44Å; L199-T213 WeakPolarHBondContact O-CB 3.29Å; L199-Y215 PolarHBondContact O-OH 3.38Å; L199-L234 HydrophobicContact CD2-CD1 3.7Å; L199-L234 HydrophobicContact CD2-CD2 4.1Å; L199-M243 WeakPolarHBondContact CD1-O 3.49Å; L199-M243 HydrophobicContact CD2-CB 4.27Å; L199-M243 HydrophobicContact CD2-CG 3.87Å; L199-M243 HydrophobicContact CD2-SD 3.87Å
200R98.3Very high96.6Very high78 Ų7836.2 Ų36.229%0.29421%0.208SC..  trans-92.9151.7167.1-170.3168.168.7-1712.4110.4F198 D202 G203 A204 T212 T213 Y215F198-R200 PolarHBondContact O-N 3.32Å; R200-D202 WeakPolarHBondContact CB-OD1 3.49Å; R200-D202 WeakPolarHBondContact CG-OD1 3.22Å; R200-D202 IonicContact CZ-OD1 2.74Å; R200-D202 IonicContact CZ-OD2 3.92Å; R200-D202 VanDerWaalsContact CZ-OD2 3.27Å; R200-D202 VanDerWaalsContact NE-CG 3.29Å; R200-D202 IonicContact NE-OD1 3.77Å; R200-D202 PolarHBondContact NE-OD1 3.2Å; R200-D202 IonicContact NE-OD2 2.79Å; R200-D202 PolarHBondContact NE-OD2 2.78Å; R200-D202 VanDerWaalsContact NE-OD2 3.11Å; R200-D202 IonicContact NH2-OD1 2.66Å; R200-D202 IonicContact NH2-OD2 3.51Å; R200-D202 PolarHBondContact NH2-OD2 3.12Å; R200-D202 PolarHBondContact O-N 3.14Å; R200-G203 PolarHBondContact O-N 3.36Å; R200-A204 WeakPolarHBondContact CB-O 3.43Å; R200-A204 PolarHBondContact N-O 3.44Å; R200-T212 WeakPolarHBondContact CD-OG1 3.4Å; R200-T212 VanDerWaalsContact CG-OG1 3.26Å; R200-T212 WeakPolarHBondContact CG-OG1 3.3Å; R200-T213 HydrophobicContact CB-CG2 4.15Å; R200-T213 HydrophobicContact CG-CG2 4.45Å; R200-Y215 PolarHBondContact O-OH 2.82Å
201N97.5Very high96.4Very high31 Ų3143.3 Ų43.317%0.16624%0.239CC..THydrogen-bonded Turntrans-60.2-16.4-176.470.6-17.1000115.7T212 Y215 D228 S245N201-T212 WeakPolarHBondContact CB-O 3.42Å; N201-T212 PolarHBondContact N-O 3.11Å; N201-Y215 WeakPolarHBondContact CA-OH 3.45Å; N201-Y215 HydrophobicContact CB-CE1 4.38Å; N201-Y215 PolarHBondContact N-OH 2.84Å; N201-Y215 VanDerWaalsContact N-OH 3.15Å; N201-D228 HydrophobicContact CB-CB 3.93Å; N201-D228 PolarHBondContact ND2-OD2 3.01Å; N201-S245 VanDerWaalsContact O-CB 3.27Å; N201-S245 WeakPolarHBondContact O-CB 3.13Å; N201-S245 PolarHBondContact O-N 3.06Å; N201-S245 PolarHBondContact O-OG 2.92Å
202D97.4Very high96.3Very high81 Ų8145.3 Ų45.343%0.43325%0.251SS..THydrogen-bonded Turntrans-86.1-6.6173.165-11.5000114R200 A204 K244R200-D202 WeakPolarHBondContact CB-OD1 3.49Å; R200-D202 WeakPolarHBondContact CG-OD1 3.22Å; R200-D202 IonicContact CZ-OD1 2.74Å; R200-D202 IonicContact CZ-OD2 3.92Å; R200-D202 VanDerWaalsContact CZ-OD2 3.27Å; R200-D202 VanDerWaalsContact NE-CG 3.29Å; R200-D202 IonicContact NE-OD1 3.77Å; R200-D202 PolarHBondContact NE-OD1 3.2Å; R200-D202 IonicContact NE-OD2 2.79Å; R200-D202 PolarHBondContact NE-OD2 2.78Å; R200-D202 VanDerWaalsContact NE-OD2 3.11Å; R200-D202 IonicContact NH2-OD1 2.66Å; R200-D202 IonicContact NH2-OD2 3.51Å; R200-D202 PolarHBondContact NH2-OD2 3.12Å; R200-D202 PolarHBondContact O-N 3.14Å; D202-A204 WeakPolarHBondContact OD1-CB 3.33Å; D202-A204 PolarHBondContact OD1-N 2.84Å; D202-A204 VanDerWaalsContact OD1-N 3.14Å; D202-K244 WeakPolarHBondContact O-CD 3.26Å
203G97.8Very high96.3Very high7 Ų745.3 Ų45.37%0.07225%0.251CS..SBendtrans101.4-5.9-179.300000114.4R200R200-G203 PolarHBondContact O-N 3.36Å
204A97.8Very high96.3Very high31 Ų3145.3 Ų45.326%0.25625%0.251SS..  trans-76.5153.217800000111.9R200 D202R200-A204 WeakPolarHBondContact CB-O 3.43Å; R200-A204 PolarHBondContact N-O 3.44Å; D202-A204 WeakPolarHBondContact OD1-CB 3.33Å; D202-A204 PolarHBondContact OD1-N 2.84Å; D202-A204 VanDerWaalsContact OD1-N 3.14Å
205L98.3Very high96.5Very high16 Ų1644.7 Ų44.78%0.08425%0.247CC..EExtended strand (participates in β ladder)trans-100.6127.1172.7-70173.3000110.7L159 I166 T193 R197 F198L159-L205 HydrophobicContact CD1-CD1 3.39Å; I166-L205 HydrophobicContact CD1-CD2 4.31Å; I166-L205 HydrophobicContact CG1-CD2 4.03Å; T193-L205 HydrophobicContact CG2-CD2 3.93Å; R197-L205 HydrophobicContact CB-CB 4.02Å; F198-L205 WeakPolarHBondContact O-CA 3.36Å
206V97.8Very high96.5Very high32 Ų3242.1 Ų42.119%0.19423%0.233CC..EExtended strand (participates in β ladder)trans-128.6150.4-176-62.90000112.3R197 F198 T208 T213R197-V206 CarbonylContact C-O 3.57Å; R197-V206 WeakPolarHBondContact CA-O 3.38Å; F198-V206 PolarHBondContact N-O 2.77Å; F198-V206 PolarHBondContact O-N 2.85Å; V206-T208 WeakPolarHBondContact CG2-O 3.27Å; V206-T213 HydrophobicContact CG2-CG2 3.48Å; V206-T213 VanDerWaalsContact CG2-CG2 3.48Å
207A95.6Very high96.5Very high78 Ų7839.4 Ų39.465%0.64522%0.219SC*.SBendtrans-75.3-24.3-176.100000114.3
208T95.2Very high96.2Very high103 Ų10337.4 Ų37.463%0.63221%0.211SC*.SBendtrans-119.8146.5-174.556.30000111.5V206V206-T208 WeakPolarHBondContact CG2-O 3.27Å
209T95.3Very high95.6Very high42 Ų4237.6 Ų37.626%0.25821%0.212SC..  trans-82.7137.6175.952.50000111.7H190 F198 T213H190-T209 HydrophobicContact CB-CG2 4.15Å; F198-T209 HydrophobicContact CD1-CG2 3.7Å; F198-T209 HydrophobicContact CD2-CG2 3.74Å; F198-T209 HydrophobicContact CE1-CG2 3.7Å; F198-T209 HydrophobicContact CE2-CG2 3.78Å; F198-T209 HydrophobicContact CG-CG2 3.7Å; F198-T209 HydrophobicContact CZ-CG2 3.76Å; T209-T213 WeakPolarHBondContact CA-OG1 3.45Å
210D95Very high94.8Very high72 Ų7241.3 Ų41.339%0.38523%0.226SC..  trans-143.5-172.116768.225.1000110.7T212 T213 G214D210-T212 PolarHBondContact O-N 3.48Å; D210-T212 WeakPolarHBondContact OD1-CA 3.29Å; D210-T212 WeakPolarHBondContact OD1-CB 3.42Å; D210-T212 PolarHBondContact OD1-N 3.2Å; D210-T212 PolarHBondContact OD1-OG1 2.67Å; D210-T212 PolarHBondContact OD2-OG1 3.04Å; D210-T213 PolarHBondContact N-OG1 2.88Å; D210-T213 PolarHBondContact O-N 3.36Å; D210-T213 VanDerWaalsContact O-N 3.14Å; D210-T213 PolarHBondContact O-OG1 2.78Å; D210-T213 PolarHBondContact OD1-N 2.81Å; D210-G214 PolarHBondContact O-N 3.14Å
211K93.9Very high93.9Very high155 Ų15540 Ų4067%0.67423%0.229SC*.G310 helixtrans-56.5-32.6178.3-66.6-176.9-179.1178.60113.8T213 G214 C229K211-T213 VanDerWaalsContact C-N 3.34Å; K211-G214 PolarHBondContact O-N 2.67Å; K211-C229 WeakPolarHBondContact O-CB 3.36Å
212T96.4Very high92.9Very high41 Ų4140.2 Ų40.225%0.25224%0.239SC..G310 helixtrans-80.1-16-177.367.80000113.3R200 N201 D210R200-T212 WeakPolarHBondContact CD-OG1 3.4Å; R200-T212 VanDerWaalsContact CG-OG1 3.26Å; R200-T212 WeakPolarHBondContact CG-OG1 3.3Å; N201-T212 WeakPolarHBondContact CB-O 3.42Å; N201-T212 PolarHBondContact N-O 3.11Å; D210-T212 PolarHBondContact O-N 3.48Å; D210-T212 WeakPolarHBondContact OD1-CA 3.29Å; D210-T212 WeakPolarHBondContact OD1-CB 3.42Å; D210-T212 PolarHBondContact OD1-N 3.2Å; D210-T212 PolarHBondContact OD1-OG1 2.67Å; D210-T212 PolarHBondContact OD2-OG1 3.04Å
213T97.5Very high92.5Very high0 Ų038.3 Ų38.30%023%0.227CC..G310 helixtrans-95.7-5.1170.7650000113.6H190 F198 L199 R200 V206 T209 D210 K211 Y215H190-T213 PolarHBondContact CE1-OG1 2.96Å; H190-T213 PolarHBondContact ND1-O 2.84Å; H190-T213 PolarHBondContact ND1-OG1 3.43Å; F198-T213 HydrophobicContact CB-CG2 4.26Å; L199-T213 VanDerWaalsContact O-CA 3.3Å; L199-T213 WeakPolarHBondContact O-CA 3.44Å; L199-T213 WeakPolarHBondContact O-CB 3.29Å; R200-T213 HydrophobicContact CB-CG2 4.15Å; R200-T213 HydrophobicContact CG-CG2 4.45Å; V206-T213 HydrophobicContact CG2-CG2 3.48Å; V206-T213 VanDerWaalsContact CG2-CG2 3.48Å; T209-T213 WeakPolarHBondContact CA-OG1 3.45Å; D210-T213 PolarHBondContact N-OG1 2.88Å; D210-T213 PolarHBondContact O-N 3.36Å; D210-T213 VanDerWaalsContact O-N 3.14Å; D210-T213 PolarHBondContact O-OG1 2.78Å; D210-T213 PolarHBondContact OD1-N 2.81Å; K211-T213 VanDerWaalsContact C-N 3.34Å; T213-Y215 VanDerWaalsContact O-CD2 3.28Å; T213-Y215 WeakPolarHBondContact O-CD2 3.18Å; T213-Y215 WeakPolarHBondContact O-CE2 3.3Å
214G96.7Very high92.2Very high1 Ų138.1 Ų38.11%0.0122%0.224CC..  trans-100.2122.8-173.100000112.5R188 D210 K211R188-G214 PolarHBondContact NH1-O 3.23Å; D210-G214 PolarHBondContact O-N 3.14Å; K211-G214 PolarHBondContact O-N 2.67Å
215Y96.2Very high92.1Very high0 Ų036.7 Ų36.70%021%0.212CC..BIsolated β-bridgetrans-115.7143.9-176.3-54.1-86000112.4Y189 L191 L199 R200 N201 T213 F226 R227 D228 L234Y189-Y215 PolarHBondContact N-O 2.86Å; Y189-Y215 WeakPolarHBondContact O-CD2 3.32Å; Y189-Y215 PolarHBondContact O-N 2.93Å; L191-Y215 HydrophobicContact CD1-CD2 3.72Å; L191-Y215 HydrophobicContact CD1-CE2 4.13Å; L191-Y215 HydrophobicContact CD1-CG 4.45Å; L199-Y215 PolarHBondContact O-OH 3.38Å; R200-Y215 PolarHBondContact O-OH 2.82Å; N201-Y215 WeakPolarHBondContact CA-OH 3.45Å; N201-Y215 HydrophobicContact CB-CE1 4.38Å; N201-Y215 PolarHBondContact N-OH 2.84Å; N201-Y215 VanDerWaalsContact N-OH 3.15Å; T213-Y215 VanDerWaalsContact O-CD2 3.28Å; T213-Y215 WeakPolarHBondContact O-CD2 3.18Å; T213-Y215 WeakPolarHBondContact O-CE2 3.3Å; Y215-F226 HydrophobicContact CD1-CB 4.11Å; Y215-F226 HydrophobicContact CG-CB 4.2Å; Y215-R227 CarbonylContact C-O 3.53Å; Y215-R227 VanDerWaalsContact CA-O 3.24Å; Y215-R227 WeakPolarHBondContact CA-O 3.45Å; Y215-D228 HydrophobicContact CD1-CB 4.12Å; Y215-D228 HydrophobicContact CE1-CB 4.05Å; Y215-L234 HydrophobicContact CD1-CD1 4.09Å; Y215-L234 HydrophobicContact CD1-CD2 4.4Å; Y215-L234 HydrophobicContact CD1-CG 4.01Å; Y215-L234 HydrophobicContact CE1-CD1 3.78Å; Y215-L234 HydrophobicContact CE1-CD2 3.52Å; Y215-L234 HydrophobicContact CE1-CG 3.61Å; Y215-L234 HydrophobicContact CE2-CD1 4.39Å
216T94.3Very high92Very high4 Ų435.9 Ų35.93%0.02521%0.208CC..EExtended strand (participates in β ladder)trans-91.6130.5167.3-45.50000108.3A99 H100 G103 R227A99-T216 HydrophobicContact CB-CG2 4.16Å; H100-T216 PolarHBondContact O-OG1 3.49Å; G103-T216 WeakPolarHBondContact CA-OG1 3.39Å; T216-R227 PolarHBondContact N-O 2.71Å; T216-R227 PolarHBondContact O-N 2.9Å
217L92.6Very high91.9Very high3 Ų336.4 Ų36.42%0.01621%0.207CC..EExtended strand (participates in β ladder)trans-76.8134.6173-53.4-176.5000109.2W105 I140 Y189 F219 V224 F226W105-L217 VanDerWaalsContact CE2-O 3.27Å; W105-L217 VanDerWaalsContact CZ2-O 3.24Å; W105-L217 WeakPolarHBondContact CZ2-O 3.35Å; W105-L217 PolarHBondContact NE1-O 3.28Å; I140-L217 HydrophobicContact CG2-CD1 3.63Å; Y189-L217 HydrophobicContact CD2-CD1 3.53Å; Y189-L217 HydrophobicContact CD2-CD2 4.17Å; Y189-L217 HydrophobicContact CD2-CG 3.55Å; Y189-L217 HydrophobicContact CE2-CD1 3.61Å; Y189-L217 HydrophobicContact CE2-CG 4.07Å; Y189-L217 HydrophobicContact CG-CD1 4.09Å; Y189-L217 HydrophobicContact CG-CD2 4.3Å; Y189-L217 HydrophobicContact CG-CG 4.15Å; L217-F219 HydrophobicContact CB-CE1 4.42Å; L217-F219 HydrophobicContact CB-CZ 4.08Å; L217-F219 HydrophobicContact CD1-CZ 4.03Å; L217-V224 HydrophobicContact CB-CG2 4.02Å; L217-V224 HydrophobicContact CD2-CG2 3.97Å; L217-V224 HydrophobicContact CG-CG2 4.43Å; L217-F226 HydrophobicContact CD2-CD1 3.49Å; L217-F226 VanDerWaalsContact CD2-CD1 3.49Å; L217-F226 HydrophobicContact CD2-CE1 3.47Å; L217-F226 VanDerWaalsContact CD2-CE1 3.47Å
218E90.6Very high91.9Very high6 Ų632.8 Ų32.83%0.02818%0.176CC..EExtended strand (participates in β ladder)trans-124.4121.6169-177.1173.6135.100108.5R220 V224 A225 Y233E218-R220 IonicContact OE1-CZ 2.82Å; E218-R220 VanDerWaalsContact OE1-CZ 3.23Å; E218-R220 IonicContact OE1-NE 2.6Å; E218-R220 PolarHBondContact OE1-NE 2.78Å; E218-R220 IonicContact OE1-NH2 3.02Å; E218-R220 PolarHBondContact OE1-NH2 3.47Å; E218-V224 CarbonylContact O-C 3.59Å; E218-V224 WeakPolarHBondContact O-CA 3.28Å; E218-A225 HydrophobicContact CB-CB 4.5Å; E218-A225 PolarHBondContact N-O 2.6Å; E218-A225 PolarHBondContact O-N 2.81Å; E218-Y233 HydrophobicContact CB-CE1 4.48Å; E218-Y233 PolarHBondContact OE2-OH 2.82Å
219F85.6Confident91.8Very high8 Ų829.8 Ų29.84%0.03516%0.16CC..EExtended strand (participates in β ladder)trans-95.9138.5-178.3-57.6-64.9000111.6I16 L52 F64 W105 V138 I140 L217 K223 V224I16-F219 HydrophobicContact CD1-CB 4.03Å; I16-F219 HydrophobicContact CD1-CD1 3.36Å; I16-F219 HydrophobicContact CD1-CD2 4.27Å; I16-F219 HydrophobicContact CD1-CE1 3.82Å; I16-F219 HydrophobicContact CD1-CG 3.63Å; I16-F219 HydrophobicContact CD1-CZ 4.46Å; I16-F219 HydrophobicContact CG1-CD1 4.31Å; I16-F219 HydrophobicContact CG1-CE1 4.29Å; I16-F219 HydrophobicContact CG2-CD1 4.45Å; I16-F219 HydrophobicContact CG2-CD2 4.12Å; I16-F219 HydrophobicContact CG2-CE1 4Å; I16-F219 HydrophobicContact CG2-CE2 3.65Å; I16-F219 HydrophobicContact CG2-CZ 3.58Å; L52-F219 HydrophobicContact CD2-CB 3.89Å; L52-F219 HydrophobicContact CD2-CD2 3.94Å; L52-F219 HydrophobicContact CD2-CG 4.33Å; F64-F219 VanDerWaalsContact CZ-O 3.26Å; F64-F219 WeakPolarHBondContact CZ-O 3.49Å; W105-F219 AromaticContact CH2-CD2 3.39Å; W105-F219 HydrophobicContact CH2-CD2 3.39Å; W105-F219 AromaticContact CH2-CE2 3.53Å; W105-F219 HydrophobicContact CH2-CE2 3.53Å; W105-F219 AromaticContact CZ2-CD2 3.69Å; W105-F219 HydrophobicContact CZ2-CD2 3.69Å; W105-F219 AromaticContact CZ2-CE2 3.8Å; W105-F219 HydrophobicContact CZ2-CE2 3.8Å; V138-F219 HydrophobicContact CG1-CE2 4.34Å; I140-F219 HydrophobicContact CG2-CZ 4.4Å; L217-F219 HydrophobicContact CB-CE1 4.42Å; L217-F219 HydrophobicContact CB-CZ 4.08Å; L217-F219 HydrophobicContact CD1-CZ 4.03Å; F219-K223 CarbonylContact C-O 3.54Å; F219-K223 VanDerWaalsContact CA-O 3.25Å; F219-K223 WeakPolarHBondContact CA-O 3.16Å; F219-V224 HydrophobicContact CD1-CB 3.96Å; F219-V224 HydrophobicContact CD1-CG2 3.94Å; F219-V224 HydrophobicContact CE1-CB 4.05Å; F219-V224 HydrophobicContact CE1-CG2 3.76Å
220R81.9Confident91.7Very high78 Ų7830.7 Ų30.729%0.29417%0.167SC..EExtended strand (participates in β ladder)trans-144.6118.8174.6-62.4-167.4180-155.6-2.4109.7E218 G222 K223 V251 L256E218-R220 IonicContact OE1-CZ 2.82Å; E218-R220 VanDerWaalsContact OE1-CZ 3.23Å; E218-R220 IonicContact OE1-NE 2.6Å; E218-R220 PolarHBondContact OE1-NE 2.78Å; E218-R220 IonicContact OE1-NH2 3.02Å; E218-R220 PolarHBondContact OE1-NH2 3.47Å; R220-G222 VanDerWaalsContact C-N 3.31Å; R220-G222 PolarHBondContact O-N 2.89Å; R220-K223 PolarHBondContact N-O 2.82Å; R220-K223 WeakPolarHBondContact O-CA 3.44Å; R220-K223 WeakPolarHBondContact O-CB 3.24Å; R220-K223 PolarHBondContact O-N 2.84Å; R220-V251 PolarHBondContact NH1-O 2.79Å; R220-L256 HydrophobicContact CB-CD2 4.1Å
221S78.1Confident91.6Very high50 Ų5027.5 Ų27.535%0.3515%0.151SC..THydrogen-bonded Turntrans50.947174.4-50.70000114.4M13 Q54 K223M13-S221 VanDerWaalsContact CE-O 3.27Å; M13-S221 WeakPolarHBondContact CE-O 3.11Å; Q54-S221 PolarHBondContact OE1-OG 2.94Å; S221-K223 PolarHBondContact O-N 2.97Å; S221-K223 PolarHBondContact O-NZ 3.32Å; S221-K223 VanDerWaalsContact O-NZ 3.1Å
222G77.9Confident91.6Very high37 Ų3724.3 Ų24.338%0.38114%0.138SC..THydrogen-bonded Turntrans61.629-177.200000113.3R220R220-G222 VanDerWaalsContact C-N 3.31Å; R220-G222 PolarHBondContact O-N 2.89Å
223K88.4Confident91.7Very high41 Ų4122.7 Ų22.718%0.17813%0.127CC..EExtended strand (participates in β ladder)trans-122.3162.8170.3-51.8-64159.6-72.50108.7V151 F219 R220 S221 L256 F257 V258V151-K223 HydrophobicContact CG2-CD 3.83Å; V151-K223 HydrophobicContact CG2-CG 4.35Å; F219-K223 CarbonylContact C-O 3.54Å; F219-K223 VanDerWaalsContact CA-O 3.25Å; F219-K223 WeakPolarHBondContact CA-O 3.16Å; R220-K223 PolarHBondContact N-O 2.82Å; R220-K223 WeakPolarHBondContact O-CA 3.44Å; R220-K223 WeakPolarHBondContact O-CB 3.24Å; R220-K223 PolarHBondContact O-N 2.84Å; S221-K223 PolarHBondContact O-N 2.97Å; S221-K223 PolarHBondContact O-NZ 3.32Å; S221-K223 VanDerWaalsContact O-NZ 3.1Å; K223-L256 HydrophobicContact CB-CB 4.2Å; K223-L256 HydrophobicContact CB-CD2 3.98Å; K223-L256 HydrophobicContact CB-CG 4.49Å; K223-F257 CarbonylContact C-O 3.48Å; K223-F257 VanDerWaalsContact CA-O 3.26Å; K223-F257 WeakPolarHBondContact CA-O 3.45Å; K223-F257 WeakPolarHBondContact CB-O 3.42Å; K223-V258 HydrophobicContact CD-CB 4.41Å; K223-V258 HydrophobicContact CD-CG2 3.37Å
224V91.6Very high91.7Very high3 Ų322.7 Ų22.72%0.01813%0.127CC..EExtended strand (participates in β ladder)trans-120.8142.2176.768.30000110.2L217 E218 F219 F226 F257 L259L217-V224 HydrophobicContact CB-CG2 4.02Å; L217-V224 HydrophobicContact CD2-CG2 3.97Å; L217-V224 HydrophobicContact CG-CG2 4.43Å; E218-V224 CarbonylContact O-C 3.59Å; E218-V224 WeakPolarHBondContact O-CA 3.28Å; F219-V224 HydrophobicContact CD1-CB 3.96Å; F219-V224 HydrophobicContact CD1-CG2 3.94Å; F219-V224 HydrophobicContact CE1-CB 4.05Å; F219-V224 HydrophobicContact CE1-CG2 3.76Å; V224-F226 HydrophobicContact CG1-CE2 3.86Å; V224-F226 HydrophobicContact CG1-CZ 3.87Å; V224-F257 HydrophobicContact CG1-CB 4.06Å; V224-F257 PolarHBondContact N-O 3.15Å; V224-F257 PolarHBondContact O-N 3.29Å; V224-L259 HydrophobicContact CG1-CD1 3.99Å; V224-L259 HydrophobicContact CG1-CD2 3.84Å; V224-L259 HydrophobicContact CG1-CG 3.63Å
225A94.6Very high91.8Very high0 Ų023.1 Ų23.10%013%0.13CC..EExtended strand (participates in β ladder)trans-116.4148.7163.700000108.9E218 Y233 V251 E255 L256E218-A225 HydrophobicContact CB-CB 4.5Å; E218-A225 PolarHBondContact N-O 2.6Å; E218-A225 PolarHBondContact O-N 2.81Å; A225-Y233 HydrophobicContact CB-CD1 3.81Å; A225-Y233 HydrophobicContact CB-CE1 4.23Å; A225-V251 HydrophobicContact CB-CB 4.49Å; A225-V251 HydrophobicContact CB-CG1 3.81Å; A225-V251 HydrophobicContact CB-CG2 3.81Å; A225-E255 WeakPolarHBondContact CA-O 3.49Å; A225-E255 VanDerWaalsContact CB-O 3.31Å; A225-E255 WeakPolarHBondContact CB-O 3.14Å; A225-L256 HydrophobicContact CB-CD2 4.49Å
226F96.4Very high91.8Very high0 Ų024 Ų240%014%0.136CC..EExtended strand (participates in β ladder)trans-110.9104.7-177.7-60.7-88.8000109.6I148 L182 L191 Y215 L217 V224 Y233 L234 M243 F257 L259I148-F226 HydrophobicContact CD1-CZ 4.15Å; L182-F226 HydrophobicContact CD2-CE1 4.2Å; L191-F226 HydrophobicContact CD1-CD1 3.81Å; L191-F226 HydrophobicContact CD1-CE1 3.82Å; L191-F226 HydrophobicContact CD2-CE1 4.44Å; L191-F226 HydrophobicContact CD2-CZ 4.45Å; L191-F226 HydrophobicContact CG-CE1 4.45Å; Y215-F226 HydrophobicContact CD1-CB 4.11Å; Y215-F226 HydrophobicContact CG-CB 4.2Å; L217-F226 HydrophobicContact CD2-CD1 3.49Å; L217-F226 VanDerWaalsContact CD2-CD1 3.49Å; L217-F226 HydrophobicContact CD2-CE1 3.47Å; L217-F226 VanDerWaalsContact CD2-CE1 3.47Å; V224-F226 HydrophobicContact CG1-CE2 3.86Å; V224-F226 HydrophobicContact CG1-CZ 3.87Å; F226-Y233 CarbonylContact O-C 3.43Å; F226-Y233 VanDerWaalsContact O-CA 3.27Å; F226-Y233 WeakPolarHBondContact O-CA 3.36Å; F226-L234 HydrophobicContact CB-CB 4.05Å; F226-L234 HydrophobicContact CB-CD1 3.6Å; F226-L234 HydrophobicContact CB-CG 3.78Å; F226-L234 HydrophobicContact CD2-CD1 4.17Å; F226-L234 HydrophobicContact CG-CD1 3.95Å; F226-L234 PolarHBondContact O-N 3.18Å; F226-M243 HydrophobicContact CD2-CE 4.49Å; F226-M243 HydrophobicContact CE2-CE 4.38Å; F226-F257 AromaticContact CD2-CD2 3.69Å; F226-F257 HydrophobicContact CD2-CD2 3.69Å; F226-F257 AromaticContact CD2-CE2 3.99Å; F226-F257 HydrophobicContact CD2-CE2 3.99Å; F226-F257 HydrophobicContact CE2-CB 4.25Å; F226-F257 AromaticContact CE2-CD2 3.71Å; F226-F257 HydrophobicContact CE2-CD2 3.71Å; F226-F257 HydrophobicContact CE2-CE2 4.37Å; F226-F257 HydrophobicContact CE2-CG 4.1Å; F226-L259 HydrophobicContact CZ-CD2 4.18Å
227R95.9Very high91.9Very high42 Ų4226.1 Ų26.116%0.15815%0.151CC..EExtended strand (participates in β ladder)trans-88124.3179.9-170.6-179.6176.5157.5-6.3110.9A99 D101 Y215 T216 K232 Y233A99-R227 PolarHBondContact O-NH1 3.1Å; D101-R227 IonicContact OD1-CZ 2.74Å; D101-R227 VanDerWaalsContact OD1-CZ 3.23Å; D101-R227 IonicContact OD1-NE 2.69Å; D101-R227 PolarHBondContact OD1-NE 2.93Å; D101-R227 IonicContact OD1-NH2 3.67Å; D101-R227 PolarHBondContact OD1-NH2 2.83Å; Y215-R227 CarbonylContact C-O 3.53Å; Y215-R227 VanDerWaalsContact CA-O 3.24Å; Y215-R227 WeakPolarHBondContact CA-O 3.45Å; T216-R227 PolarHBondContact N-O 2.71Å; T216-R227 PolarHBondContact O-N 2.9Å; R227-K232 CarbonylContact C-O 3.52Å; R227-K232 VanDerWaalsContact CA-O 3.3Å; R227-K232 WeakPolarHBondContact CA-O 3.38Å; R227-Y233 HydrophobicContact CB-CD1 3.88Å; R227-Y233 HydrophobicContact CB-CE1 3.53Å; R227-Y233 HydrophobicContact CG-CD1 4.39Å; R227-Y233 HydrophobicContact CG-CE1 3.9Å; R227-Y233 HydrophobicContact CG-CE2 4.44Å
228D95.3Very high92.1Very high2 Ų227.9 Ų27.91%0.01117%0.17CC..  trans-80.3178.3178.479.56.7000113.4N201 Y215 S230 G231 K232 S245N201-D228 HydrophobicContact CB-CB 3.93Å; N201-D228 PolarHBondContact ND2-OD2 3.01Å; Y215-D228 HydrophobicContact CD1-CB 4.12Å; Y215-D228 HydrophobicContact CE1-CB 4.05Å; D228-S230 PolarHBondContact O-N 3.29Å; D228-S230 VanDerWaalsContact O-N 3.12Å; D228-S230 VanDerWaalsContact OD1-CA 3.29Å; D228-S230 WeakPolarHBondContact OD1-CA 3.23Å; D228-S230 WeakPolarHBondContact OD1-CB 3.38Å; D228-S230 PolarHBondContact OD1-N 2.81Å; D228-S230 PolarHBondContact OD1-OG 2.99Å; D228-S230 PolarHBondContact OD2-OG 2.77Å; D228-G231 PolarHBondContact O-N 2.8Å; D228-G231 PolarHBondContact OD1-N 2.79Å; D228-G231 VanDerWaalsContact OD1-N 3.11Å; D228-K232 PolarHBondContact N-O 2.62Å; D228-K232 PolarHBondContact OD1-N 3.26Å; D228-S245 WeakPolarHBondContact CB-OG 3.38Å; D228-S245 VanDerWaalsContact CG-OG 3.28Å; D228-S245 VanDerWaalsContact OD2-CB 3.23Å; D228-S245 WeakPolarHBondContact OD2-CB 3.28Å; D228-S245 PolarHBondContact OD2-OG 3.18Å
229C93.2Very high92.3Very high41 Ų4134 Ų3428%0.27721%0.21SC..THydrogen-bonded Turntrans-66.7-6.9179.667.20000115.4K211K211-C229 WeakPolarHBondContact O-CB 3.36Å
230S93Very high92.8Very high60 Ų6034.9 Ų34.942%0.4222%0.217SC..THydrogen-bonded Turntrans-108.45.7178.1740000113.2D228 K232D228-S230 PolarHBondContact O-N 3.29Å; D228-S230 VanDerWaalsContact O-N 3.12Å; D228-S230 VanDerWaalsContact OD1-CA 3.29Å; D228-S230 WeakPolarHBondContact OD1-CA 3.23Å; D228-S230 WeakPolarHBondContact OD1-CB 3.38Å; D228-S230 PolarHBondContact OD1-N 2.81Å; D228-S230 PolarHBondContact OD1-OG 2.99Å; D228-S230 PolarHBondContact OD2-OG 2.77Å; S230-K232 VanDerWaalsContact C-N 3.32Å; S230-K232 WeakPolarHBondContact OG-CD 3.4Å
231G93Very high93.5Very high5 Ų531.1 Ų31.15%0.05220%0.203CC..SBendtrans79.112.3-179.300000114.8D101 D228D101-G231 WeakPolarHBondContact OD1-CA 3.16Å; D101-G231 PolarHBondContact OD1-N 2.95Å; D228-G231 PolarHBondContact O-N 2.8Å; D228-G231 PolarHBondContact OD1-N 2.79Å; D228-G231 VanDerWaalsContact OD1-N 3.11Å
232K95.5Very high94.5Very high89 Ų8929.7 Ų29.739%0.38719%0.193SC..  trans-97.3166.9175.3-60.6172.6-172.6172.10110R227 D228 S230 G246R227-K232 CarbonylContact C-O 3.52Å; R227-K232 VanDerWaalsContact CA-O 3.3Å; R227-K232 WeakPolarHBondContact CA-O 3.38Å; D228-K232 PolarHBondContact N-O 2.62Å; D228-K232 PolarHBondContact OD1-N 3.26Å; S230-K232 VanDerWaalsContact C-N 3.32Å; S230-K232 WeakPolarHBondContact OG-CD 3.4Å; K232-G246 WeakPolarHBondContact CD-O 3.41Å
233Y97.1Very high95.5Very high6 Ų628 Ų282%0.02418%0.175CC..BIsolated β-bridgetrans-118.6146.3-175.7-64.3-91.6000112.1E218 A225 F226 R227 S245 G246 A249 V251 E255E218-Y233 HydrophobicContact CB-CE1 4.48Å; E218-Y233 PolarHBondContact OE2-OH 2.82Å; A225-Y233 HydrophobicContact CB-CD1 3.81Å; A225-Y233 HydrophobicContact CB-CE1 4.23Å; F226-Y233 CarbonylContact O-C 3.43Å; F226-Y233 VanDerWaalsContact O-CA 3.27Å; F226-Y233 WeakPolarHBondContact O-CA 3.36Å; R227-Y233 HydrophobicContact CB-CD1 3.88Å; R227-Y233 HydrophobicContact CB-CE1 3.53Å; R227-Y233 HydrophobicContact CG-CD1 4.39Å; R227-Y233 HydrophobicContact CG-CE1 3.9Å; R227-Y233 HydrophobicContact CG-CE2 4.44Å; Y233-S245 CarbonylContact O-C 3.5Å; Y233-S245 WeakPolarHBondContact O-CA 3.29Å; Y233-G246 PolarHBondContact O-N 3.36Å; Y233-A249 WeakPolarHBondContact CE2-O 3.48Å; Y233-V251 HydrophobicContact CD1-CG2 3.65Å; Y233-V251 HydrophobicContact CD2-CG2 4.17Å; Y233-V251 HydrophobicContact CE1-CG2 3.31Å; Y233-V251 HydrophobicContact CE2-CG2 3.93Å; Y233-V251 HydrophobicContact CG-CG2 4.06Å; Y233-V251 VanDerWaalsContact CZ-CG2 3.5Å; Y233-E255 VanDerWaalsContact CB-CG 3.41Å; Y233-E255 HydrophobicContact CG-CG 4.23Å
234L98.2Very high95.9Very high0 Ų029.4 Ų29.40%018%0.181CC..EExtended strand (participates in β ladder)trans-60.4134.6168.6-66.2-176.2000110.4L191 L199 Y215 F226 M243 K244 E255 F257L191-L234 HydrophobicContact CD2-CD1 4.05Å; L199-L234 HydrophobicContact CD2-CD1 3.7Å; L199-L234 HydrophobicContact CD2-CD2 4.1Å; Y215-L234 HydrophobicContact CD1-CD1 4.09Å; Y215-L234 HydrophobicContact CD1-CD2 4.4Å; Y215-L234 HydrophobicContact CD1-CG 4.01Å; Y215-L234 HydrophobicContact CE1-CD1 3.78Å; Y215-L234 HydrophobicContact CE1-CD2 3.52Å; Y215-L234 HydrophobicContact CE1-CG 3.61Å; Y215-L234 HydrophobicContact CE2-CD1 4.39Å; F226-L234 HydrophobicContact CB-CB 4.05Å; F226-L234 HydrophobicContact CB-CD1 3.6Å; F226-L234 HydrophobicContact CB-CG 3.78Å; F226-L234 HydrophobicContact CD2-CD1 4.17Å; F226-L234 HydrophobicContact CG-CD1 3.95Å; F226-L234 PolarHBondContact O-N 3.18Å; L234-M243 HydrophobicContact CB-CG 4.39Å; L234-M243 HydrophobicContact CD1-CE 4.23Å; L234-M243 HydrophobicContact CD1-CG 4.19Å; L234-M243 HydrophobicContact CD1-SD 4.19Å; L234-K244 WeakPolarHBondContact CA-O 3.29Å; L234-K244 VanDerWaalsContact CD2-C 3.49Å; L234-E255 WeakPolarHBondContact O-CA 3.4Å; L234-F257 HydrophobicContact CB-CE2 4.33Å; L234-F257 WeakPolarHBondContact O-CE2 3.42Å
235A97.9Very high96.2Very high10 Ų1030.3 Ų30.38%0.08319%0.187CC..EExtended strand (participates in β ladder)trans-148.5151.317300000110.2S237 K244 D254 E255A235-S237 PolarHBondContact O-N 3.12Å; A235-K244 PolarHBondContact N-O 2.89Å; A235-K244 PolarHBondContact O-N 3.24Å; A235-K244 VanDerWaalsContact O-O 3.07Å; A235-D254 HydrophobicContact CB-CB 4.37Å; A235-E255 HydrophobicContact CB-CG 4.33Å
236P97.4Very high96.1Very high19 Ų1931.4 Ų31.412%0.12320%0.199CC..EExtended strand (participates in β ladder)trans-67.9125.7175-1224000112S150 R153 I168 D254 F257S150-P236 WeakPolarHBondContact OG-CG 3.48Å; R153-P236 HydrophobicContact CG-CB 3.73Å; R153-P236 HydrophobicContact CG-CG 3.76Å; I168-P236 HydrophobicContact CB-CB 4.31Å; I168-P236 HydrophobicContact CD1-CB 3.89Å; I168-P236 HydrophobicContact CD1-CG 3.7Å; I168-P236 HydrophobicContact CG2-CG 4.5Å; P236-D254 WeakPolarHBondContact CD-O 3.39Å; P236-F257 HydrophobicContact CG-CE1 4.42Å
237S96.6Very high95.7Very high48 Ų4841.4 Ų41.434%0.33624%0.242SC..EExtended strand (participates in β ladder)trans-120.7142.1-177.3-1640000112.9A235 G241 T242 K244A235-S237 PolarHBondContact O-N 3.12Å; S237-G241 CarbonylContact O-C 3.59Å; S237-G241 VanDerWaalsContact O-CA 3.25Å; S237-G241 WeakPolarHBondContact O-CA 3.49Å; S237-G241 PolarHBondContact O-N 2.66Å; S237-T242 PolarHBondContact N-O 3.23Å; S237-T242 PolarHBondContact O-N 2.77Å; S237-K244 WeakPolarHBondContact OG-CE 3.26Å
238G95.6Very high95.1Very high41 Ų4141.6 Ų41.642%0.42325%0.25SS..THydrogen-bonded Turntrans70.9-173.4176.700000114.7R153 G241R153-G238 PolarHBondContact NH1-O 2.95Å; R153-G238 VanDerWaalsContact NH1-O 3.12Å; R153-G238 PolarHBondContact NH2-O 2.87Å; G238-G241 PolarHBondContact O-N 3.22Å
239P95.2Very high94.7Very high133 Ų13344.9 Ų44.986%0.86428%0.278SS*.THydrogen-bonded Turntrans-60.6-51.1-173.3-2636.1000114.2R153 G241R153-P239 PolarHBondContact NH1-O 3.12Å; R153-P239 VanDerWaalsContact NH1-O 3.15Å; P239-G241 PolarHBondContact O-N 3.09Å
240S95.9Very high94.5Very high27 Ų2752.8 Ų52.819%0.18930%0.301CS..THydrogen-bonded Turntrans-71.6-12.1176.353.20000113.5E165 I168E165-S240 WeakPolarHBondContact OE1-CB 3.43Å; E165-S240 PolarHBondContact OE1-OG 2.79Å; I168-S240 CarbonylContact C-O 3.56Å; I168-S240 PolarHBondContact N-O 3.11Å
241G97.3Very high94.4Very high0 Ų050.6 Ų50.60%029%0.286CS..THydrogen-bonded Turntrans71.939-177.400000113.1I168 S237 G238 P239 M243I168-G241 WeakPolarHBondContact CB-O 3.35Å; I168-G241 WeakPolarHBondContact CG1-O 3.41Å; I168-G241 PolarHBondContact N-O 2.9Å; S237-G241 CarbonylContact O-C 3.59Å; S237-G241 VanDerWaalsContact O-CA 3.25Å; S237-G241 WeakPolarHBondContact O-CA 3.49Å; S237-G241 PolarHBondContact O-N 2.66Å; G238-G241 PolarHBondContact O-N 3.22Å; P239-G241 PolarHBondContact O-N 3.09Å; G241-M243 PolarHBondContact O-N 3.15Å; G241-M243 VanDerWaalsContact O-N 3.13Å
242T98.3Very high94.3Very high20 Ų2052 Ų5212%0.12330%0.301CS..EExtended strand (participates in β ladder)trans-37.7118.6172-48.30000111E165 S237 K244E165-T242 HydrophobicContact CB-CG2 4.3Å; E165-T242 VanDerWaalsContact CD-OG1 3.28Å; E165-T242 PolarHBondContact OE1-OG1 3.35Å; E165-T242 VanDerWaalsContact OE2-CB 3.28Å; E165-T242 WeakPolarHBondContact OE2-CB 3.35Å; E165-T242 WeakPolarHBondContact OE2-CG2 3.24Å; E165-T242 PolarHBondContact OE2-OG1 2.93Å; S237-T242 PolarHBondContact N-O 3.23Å; S237-T242 PolarHBondContact O-N 2.77Å; T242-K244 HydrophobicContact CG2-CD 4.33Å; T242-K244 PolarHBondContact O-N 3.4Å
243M98.4Very high94.1Very high1 Ų155.5 Ų55.51%0.00532%0.316CS..EExtended strand (participates in β ladder)trans-75.3108.6178.8-166.5176.8-139.300109.6I148 I166 I168 L191 L199 F226 L234 G241 F257I148-M243 HydrophobicContact CG2-CE 4.1Å; I166-M243 HydrophobicContact CB-CB 4.04Å; I166-M243 HydrophobicContact CG2-CB 3.99Å; I166-M243 HydrophobicContact CG2-SD 4.1Å; I166-M243 PolarHBondContact O-N 3.4Å; I168-M243 HydrophobicContact CD1-CB 3.8Å; I168-M243 HydrophobicContact CD1-CE 4.21Å; I168-M243 HydrophobicContact CD1-CG 3.91Å; I168-M243 HydrophobicContact CD1-SD 4.37Å; I168-M243 HydrophobicContact CG1-CB 4.28Å; L191-M243 HydrophobicContact CD2-CE 4.24Å; L191-M243 HydrophobicContact CD2-SD 3.84Å; L199-M243 WeakPolarHBondContact CD1-O 3.49Å; L199-M243 HydrophobicContact CD2-CB 4.27Å; L199-M243 HydrophobicContact CD2-CG 3.87Å; L199-M243 HydrophobicContact CD2-SD 3.87Å; F226-M243 HydrophobicContact CD2-CE 4.49Å; F226-M243 HydrophobicContact CE2-CE 4.38Å; L234-M243 HydrophobicContact CB-CG 4.39Å; L234-M243 HydrophobicContact CD1-CE 4.23Å; L234-M243 HydrophobicContact CD1-CG 4.19Å; L234-M243 HydrophobicContact CD1-SD 4.19Å; G241-M243 PolarHBondContact O-N 3.15Å; G241-M243 VanDerWaalsContact O-N 3.13Å; M243-F257 HydrophobicContact CE-CD1 3.98Å; M243-F257 HydrophobicContact CE-CD2 4.43Å; M243-F257 HydrophobicContact CE-CE1 3.55Å; M243-F257 HydrophobicContact CE-CE2 4.03Å; M243-F257 HydrophobicContact CE-CG 4.41Å; M243-F257 HydrophobicContact CE-CZ 3.57Å
244K98.2Very high94.1Very high71 Ų7159 Ų5931%0.30934%0.335SS..EExtended strand (participates in β ladder)trans-154.1167.717765.6-175.9177.2-166.20111.6D202 L234 A235 S237 T242 G246D202-K244 WeakPolarHBondContact O-CD 3.26Å; L234-K244 WeakPolarHBondContact CA-O 3.29Å; L234-K244 VanDerWaalsContact CD2-C 3.49Å; A235-K244 PolarHBondContact N-O 2.89Å; A235-K244 PolarHBondContact O-N 3.24Å; A235-K244 VanDerWaalsContact O-O 3.07Å; S237-K244 WeakPolarHBondContact OG-CE 3.26Å; T242-K244 HydrophobicContact CG2-CD 4.33Å; T242-K244 PolarHBondContact O-N 3.4Å; K244-G246 PolarHBondContact O-N 3.25Å
245S97.4Very high94Very high21 Ų2159.9 Ų59.915%0.14734%0.339CS..EExtended strand (participates in β ladder)trans-63.5124.1175.6-72.50000110.9N201 D228 Y233N201-S245 VanDerWaalsContact O-CB 3.27Å; N201-S245 WeakPolarHBondContact O-CB 3.13Å; N201-S245 PolarHBondContact O-N 3.06Å; N201-S245 PolarHBondContact O-OG 2.92Å; D228-S245 WeakPolarHBondContact CB-OG 3.38Å; D228-S245 VanDerWaalsContact CG-OG 3.28Å; D228-S245 VanDerWaalsContact OD2-CB 3.23Å; D228-S245 WeakPolarHBondContact OD2-CB 3.28Å; D228-S245 PolarHBondContact OD2-OG 3.18Å; Y233-S245 CarbonylContact O-C 3.5Å; Y233-S245 WeakPolarHBondContact O-CA 3.29Å
246G92.7Very high93.8Very high24 Ų2460.7 Ų60.725%0.24734%0.342CS..  trans-72.1-167.6173.600000112.4K232 Y233 K244K232-G246 WeakPolarHBondContact CD-O 3.41Å; Y233-G246 PolarHBondContact O-N 3.36Å; K244-G246 PolarHBondContact O-N 3.25Å
247K87.2Confident93.8Very high209 Ų20959.8 Ų59.891%0.90934%0.336SS*.SBendtrans-92.2-15.7174.6-63.9-177.7-178.2178.70113
248S84.1Confident93.7Very high47 Ų4758.7 Ų58.733%0.32933%0.327SS..  trans-80.5136.6-175-173.10000111.8R250S248-R250 VanDerWaalsContact C-N 3.34Å; S248-R250 PolarHBondContact OG-N 2.62Å; S248-R250 PolarHBondContact OG-O 3.18Å
249A87Confident93.6Very high71 Ų7157.6 Ų57.659%0.58731%0.311SS*.SBendtrans-94.78.7167.100000112.3Y233Y233-A249 WeakPolarHBondContact CE2-O 3.48Å
250R88.8Confident93.4Very high206 Ų20654.1 Ų54.178%0.77728%0.283SS*.SBendtrans-124.2138.9176.6-62.6-175.7-175.6-172.61.2109.5S248 G252S248-R250 VanDerWaalsContact C-N 3.34Å; S248-R250 PolarHBondContact OG-N 2.62Å; S248-R250 PolarHBondContact OG-O 3.18Å; R250-G252 PolarHBondContact O-N 2.72Å
251V90.8Very high93.1Very high15 Ų1554.7 Ų54.79%0.09128%0.283CS..  trans-73112.4174.1-176.40000109.3R220 A225 Y233 E255 L256R220-V251 PolarHBondContact NH1-O 2.79Å; A225-V251 HydrophobicContact CB-CB 4.49Å; A225-V251 HydrophobicContact CB-CG1 3.81Å; A225-V251 HydrophobicContact CB-CG2 3.81Å; Y233-V251 HydrophobicContact CD1-CG2 3.65Å; Y233-V251 HydrophobicContact CD2-CG2 4.17Å; Y233-V251 HydrophobicContact CE1-CG2 3.31Å; Y233-V251 HydrophobicContact CE2-CG2 3.93Å; Y233-V251 HydrophobicContact CG-CG2 4.06Å; Y233-V251 VanDerWaalsContact CZ-CG2 3.5Å; V251-E255 HydrophobicContact CG1-CB 4.01Å; V251-L256 HydrophobicContact CG1-CD2 3.5Å; V251-L256 VanDerWaalsContact CG1-CD2 3.5Å; V251-L256 HydrophobicContact CG1-CG 3.97Å
252G91.1Very high93Very high35 Ų3554.8 Ų54.836%0.36128%0.284SS..  trans-101.4-162.6165.200000110.8R250 D254 E255 L256R250-G252 PolarHBondContact O-N 2.72Å; G252-D254 VanDerWaalsContact C-N 3.3Å; G252-D254 PolarHBondContact O-N 2.72Å; G252-E255 VanDerWaalsContact CA-OE2 3.27Å; G252-E255 WeakPolarHBondContact CA-OE2 3.43Å; G252-E255 PolarHBondContact N-OE2 2.84Å; G252-L256 WeakPolarHBondContact O-CG 3.42Å
253K92Very high92.8Very high162 Ų16255.6 Ų55.670%0.70429%0.286SS*.SBendtrans-67.4-32.3177.6-70.4-174.7178.9179.90112.6T152 E255 L256T152-K253 PolarHBondContact OG1-O 2.88Å; T152-K253 VanDerWaalsContact OG1-O 3.07Å; K253-E255 VanDerWaalsContact C-N 3.27Å; K253-E255 PolarHBondContact O-N 2.89Å; K253-L256 PolarHBondContact O-N 2.87Å
254D95.1Very high92.7Very high80 Ų8055.5 Ų55.543%0.42829%0.286SS..THydrogen-bonded Turntrans-70.2-27-175-63.8-11.8000112.6T152 A235 P236 G252T152-D254 VanDerWaalsContact CB-OD1 3.3Å; T152-D254 WeakPolarHBondContact CB-OD1 3.32Å; T152-D254 WeakPolarHBondContact CG2-OD1 3.21Å; T152-D254 VanDerWaalsContact OG1-CA 3.31Å; T152-D254 WeakPolarHBondContact OG1-CA 3.47Å; T152-D254 PolarHBondContact OG1-N 2.8Å; T152-D254 PolarHBondContact OG1-OD1 2.89Å; A235-D254 HydrophobicContact CB-CB 4.37Å; P236-D254 WeakPolarHBondContact CD-O 3.39Å; G252-D254 VanDerWaalsContact C-N 3.3Å; G252-D254 PolarHBondContact O-N 2.72Å
255E96.5Very high92.6Very high17 Ų1752.1 Ų52.18%0.07927%0.271CS..THydrogen-bonded Turntrans-87.1-1.6178.5-66.269.3-146.900113.6A225 Y233 L234 A235 V251 G252 K253 F257A225-E255 WeakPolarHBondContact CA-O 3.49Å; A225-E255 VanDerWaalsContact CB-O 3.31Å; A225-E255 WeakPolarHBondContact CB-O 3.14Å; Y233-E255 VanDerWaalsContact CB-CG 3.41Å; Y233-E255 HydrophobicContact CG-CG 4.23Å; L234-E255 WeakPolarHBondContact O-CA 3.4Å; A235-E255 HydrophobicContact CB-CG 4.33Å; V251-E255 HydrophobicContact CG1-CB 4.01Å; G252-E255 VanDerWaalsContact CA-OE2 3.27Å; G252-E255 WeakPolarHBondContact CA-OE2 3.43Å; G252-E255 PolarHBondContact N-OE2 2.84Å; K253-E255 VanDerWaalsContact C-N 3.27Å; K253-E255 PolarHBondContact O-N 2.89Å; E255-F257 WeakPolarHBondContact O-CD2 3.26Å; E255-F257 WeakPolarHBondContact O-CE2 3.25Å
256L95.3Very high92.7Very high28 Ų2851.1 Ų51.115%0.14726%0.264CS..  trans-96.3131-176.9-67.2176.6000112.6V151 R220 K223 A225 V251 G252 K253V151-L256 HydrophobicContact CB-CB 4.3Å; V151-L256 WeakPolarHBondContact CB-O 3.39Å; V151-L256 HydrophobicContact CG2-CB 4Å; V151-L256 WeakPolarHBondContact CG2-O 3.49Å; V151-L256 PolarHBondContact N-O 3.26Å; V151-L256 VanDerWaalsContact N-O 3.11Å; R220-L256 HydrophobicContact CB-CD2 4.1Å; K223-L256 HydrophobicContact CB-CB 4.2Å; K223-L256 HydrophobicContact CB-CD2 3.98Å; K223-L256 HydrophobicContact CB-CG 4.49Å; A225-L256 HydrophobicContact CB-CD2 4.49Å; V251-L256 HydrophobicContact CG1-CD2 3.5Å; V251-L256 VanDerWaalsContact CG1-CD2 3.5Å; V251-L256 HydrophobicContact CG1-CG 3.97Å; G252-L256 WeakPolarHBondContact O-CG 3.42Å; K253-L256 PolarHBondContact O-N 2.87Å
257F96.3Very high93Very high0 Ų050 Ų500%025%0.252CS..EExtended strand (participates in β ladder)trans-125.4151.7177.6-54.6-85.4000111.7I148 F149 I168 K223 V224 F226 L234 P236 M243 E255I148-F257 HydrophobicContact CG2-CB 3.75Å; I148-F257 HydrophobicContact CG2-CD1 3.68Å; I148-F257 HydrophobicContact CG2-CG 3.88Å; F149-F257 CarbonylContact O-C 3.58Å; F149-F257 WeakPolarHBondContact O-CA 3.24Å; I168-F257 HydrophobicContact CD1-CE1 3.9Å; K223-F257 CarbonylContact C-O 3.48Å; K223-F257 VanDerWaalsContact CA-O 3.26Å; K223-F257 WeakPolarHBondContact CA-O 3.45Å; K223-F257 WeakPolarHBondContact CB-O 3.42Å; V224-F257 HydrophobicContact CG1-CB 4.06Å; V224-F257 PolarHBondContact N-O 3.15Å; V224-F257 PolarHBondContact O-N 3.29Å; F226-F257 AromaticContact CD2-CD2 3.69Å; F226-F257 HydrophobicContact CD2-CD2 3.69Å; F226-F257 AromaticContact CD2-CE2 3.99Å; F226-F257 HydrophobicContact CD2-CE2 3.99Å; F226-F257 HydrophobicContact CE2-CB 4.25Å; F226-F257 AromaticContact CE2-CD2 3.71Å; F226-F257 HydrophobicContact CE2-CD2 3.71Å; F226-F257 HydrophobicContact CE2-CE2 4.37Å; F226-F257 HydrophobicContact CE2-CG 4.1Å; L234-F257 HydrophobicContact CB-CE2 4.33Å; L234-F257 WeakPolarHBondContact O-CE2 3.42Å; P236-F257 HydrophobicContact CG-CE1 4.42Å; M243-F257 HydrophobicContact CE-CD1 3.98Å; M243-F257 HydrophobicContact CE-CD2 4.43Å; M243-F257 HydrophobicContact CE-CE1 3.55Å; M243-F257 HydrophobicContact CE-CE2 4.03Å; M243-F257 HydrophobicContact CE-CG 4.41Å; M243-F257 HydrophobicContact CE-CZ 3.57Å; E255-F257 WeakPolarHBondContact O-CD2 3.26Å; E255-F257 WeakPolarHBondContact O-CE2 3.25Å
258V94.3Very high93.5Very high25 Ų2540 Ų4015%0.15221%0.209CC..EExtended strand (participates in β ladder)trans-99133.9165.3-175.50000107.7F149 V151 K223 E260F149-V258 HydrophobicContact CB-CB 4.2Å; F149-V258 HydrophobicContact CD1-CB 4.4Å; F149-V258 HydrophobicContact CD1-CG2 4.11Å; F149-V258 PolarHBondContact N-O 2.89Å; F149-V258 PolarHBondContact O-N 3.25Å; V151-V258 HydrophobicContact CG2-CG2 4.36Å; K223-V258 HydrophobicContact CD-CB 4.41Å; K223-V258 HydrophobicContact CD-CG2 3.37Å; V258-E260 HydrophobicContact CG1-CG 3.94Å
259L92.9Very high94.2Very high18 Ų1839.1 Ų39.19%0.09420%0.201CC..EExtended strand (participates in β ladder)trans-95.1124.2167.2-58.6-178.1000108.3M142 V146 I148 L182 V224 F226M142-L259 HydrophobicContact SD-CD1 4.33Å; V146-L259 HydrophobicContact CG2-CD2 4.21Å; I148-L259 HydrophobicContact CD1-CD2 4.43Å; I148-L259 HydrophobicContact CG1-CD2 3.91Å; L182-L259 HydrophobicContact CD1-CD1 3.93Å; V224-L259 HydrophobicContact CG1-CD1 3.99Å; V224-L259 HydrophobicContact CG1-CD2 3.84Å; V224-L259 HydrophobicContact CG1-CG 3.63Å; F226-L259 HydrophobicContact CZ-CD2 4.18Å
260E92.2Very high94.7Very high59 Ų5935.9 Ų35.928%0.27618%0.175SC..EExtended strand (participates in β ladder)trans-116.1141.6175.4-62.9-179.9176.500108.5V146 N147 Y156 V258 S262V146-E260 CarbonylContact C-O 3.55Å; V146-E260 WeakPolarHBondContact CA-O 3.36Å; V146-E260 VanDerWaalsContact CB-O 3.26Å; V146-E260 WeakPolarHBondContact CB-O 3.4Å; N147-E260 HydrophobicContact CB-CB 4.48Å; N147-E260 PolarHBondContact N-O 2.76Å; N147-E260 PolarHBondContact O-N 3.48Å; Y156-E260 VanDerWaalsContact CE1-OE2 3.24Å; Y156-E260 WeakPolarHBondContact CE1-OE2 3.31Å; Y156-E260 PolarHBondContact OH-OE1 3.2Å; Y156-E260 PolarHBondContact OH-OE2 3.31Å; V258-E260 HydrophobicContact CG1-CG 3.94Å; E260-S262 PolarHBondContact O-N 2.88Å
261Q90.3Very high95Very high40 Ų4028.3 Ų28.319%0.18716%0.16CC..EExtended strand (participates in β ladder)trans-65132.2175.6-175.6165.114.200109.7H263 N462 E497Q261-H263 PolarHBondContact O-N 2.97Å; Q261-N462 PolarHBondContact NE2-ND2 3.2Å; Q261-N462 PolarHBondContact OE1-ND2 3.44Å; Q261-E497 PolarHBondContact NE2-OE1 3.28Å
262S94.1Very high95.2Very high1 Ų130.6 Ų30.61%0.00717%0.172CC..  trans-75.9111.5176-179.60000109.9Q145 N147 E260 N385 R386Q145-S262 PolarHBondContact O-N 2.99Å; N147-S262 WeakPolarHBondContact OD1-CA 3.41Å; E260-S262 PolarHBondContact O-N 2.88Å; S262-N385 PolarHBondContact OG-ND2 2.99Å; S262-R386 PolarHBondContact O-NH2 2.59Å; S262-R386 PolarHBondContact OG-NH1 3.43Å
263H93.9Very high95.5Very high37 Ų3736.9 Ų36.917%0.17119%0.192CC..  trans-72.5156.1174.2-71.5-67.8000111.9Q261 Q265 Q298 N385 Y461 N462Q261-H263 PolarHBondContact O-N 2.97Å; H263-Q265 PolarHBondContact O-N 3.43Å; H263-Q298 HydrophobicContact CB-CG 3.57Å; H263-N385 PolarHBondContact O-ND2 3.39Å; H263-Y461 AromaticContact CE1-CE2 3.94Å; H263-Y461 AromaticContact CE1-CZ 3.89Å; H263-N462 PolarHBondContact CE1-OD1 2.76Å; H263-N462 PolarHBondContact ND1-OD1 2.74Å
264P95.8Very high95.8Very high0 Ų034.1 Ų34.10%018%0.177CC..  trans-64.1134.2175.630.8-38.1000110.4Q298 V299 L383 F458 Y498P264-Q298 CarbonylContact O-C 3.55Å; P264-Q298 WeakPolarHBondContact O-CA 3.23Å; P264-V299 HydrophobicContact CG-CB 3.87Å; P264-V299 VanDerWaalsContact CG-O 3.29Å; P264-V299 WeakPolarHBondContact CG-O 3.5Å; P264-V299 PolarHBondContact O-N 2.69Å; P264-L383 HydrophobicContact CB-CD1 3.83Å; P264-F458 HydrophobicContact CB-CD1 4.27Å; P264-F458 HydrophobicContact CB-CE1 3.63Å; P264-F458 HydrophobicContact CB-CZ 4.03Å; P264-F458 HydrophobicContact CG-CD1 4.35Å; P264-F458 HydrophobicContact CG-CE1 4.2Å; P264-Y498 HydrophobicContact CB-CE2 3.65Å; P264-Y498 VanDerWaalsContact CD-OH 3.24Å; P264-Y498 WeakPolarHBondContact CD-OH 3.27Å; P264-Y498 HydrophobicContact CG-CE2 3.95Å; P264-Y498 WeakPolarHBondContact CG-OH 3.24Å
265Q97.8Very high95.9Very high0 Ų030.9 Ų30.90%016%0.16CC..EExtended strand (participates in β ladder)trans-121.8129.6172.7-66.8178.615.700109.5P173 H263 V296 F297 Q298 I384 N385P173-Q265 PolarHBondContact O-NE2 2.92Å; H263-Q265 PolarHBondContact O-N 3.43Å; Q265-V296 HydrophobicContact CB-CG1 3.71Å; Q265-V296 HydrophobicContact CG-CG1 4.37Å; Q265-F297 CarbonylContact C-O 3.54Å; Q265-F297 WeakPolarHBondContact CA-O 3.44Å; Q265-Q298 HydrophobicContact CG-CB 4.04Å; Q265-Q298 HydrophobicContact CG-CG 4.47Å; Q265-I384 HydrophobicContact CB-CG1 4.32Å; Q265-I384 VanDerWaalsContact O-CG1 3.27Å; Q265-I384 WeakPolarHBondContact O-CG1 3.47Å; Q265-I384 PolarHBondContact O-N 2.88Å; Q265-N385 HydrophobicContact CB-CB 4.14Å; Q265-N385 PolarHBondContact N-OD1 3.2Å
266V98.3Very high96Very high0 Ų030.1 Ų30.10%016%0.157CC..EExtended strand (participates in β ladder)trans-127153.2-169.5-55.80000111.9L268 F297 V299 F310 M381 K382 L383 F458V266-L268 HydrophobicContact CG2-CG 4.38Å; V266-F297 PolarHBondContact N-O 3.31Å; V266-F297 PolarHBondContact O-N 2.9Å; V266-V299 HydrophobicContact CB-CG2 4.21Å; V266-V299 HydrophobicContact CG1-CG2 3.7Å; V266-V299 HydrophobicContact CG2-CG2 3.45Å; V266-V299 VanDerWaalsContact CG2-CG2 3.45Å; V266-F310 HydrophobicContact CG2-CE1 4.34Å; V266-M381 HydrophobicContact CB-CG 3.68Å; V266-M381 HydrophobicContact CB-SD 4.17Å; V266-M381 HydrophobicContact CG1-CG 3.77Å; V266-M381 HydrophobicContact CG1-SD 3.98Å; V266-M381 HydrophobicContact CG2-CG 3.89Å; V266-M381 HydrophobicContact CG2-SD 3.88Å; V266-K382 CarbonylContact C-O 3.51Å; V266-K382 WeakPolarHBondContact CA-O 3.47Å; V266-K382 WeakPolarHBondContact CB-O 3.39Å; V266-L383 HydrophobicContact CG1-CD1 4.4Å; V266-F458 HydrophobicContact CG1-CE2 4.25Å; V266-F458 HydrophobicContact CG1-CZ 4.49Å
267V98.5Very high96.2Very high0 Ų028.8 Ų28.80%015%0.15CC..EExtended strand (participates in β ladder)trans-104136160.5174.60000107.4N275 E291 V296 K382 I384V267-N275 HydrophobicContact CG1-CB 4.02Å; V267-E291 HydrophobicContact CG1-CG 4.39Å; V267-E291 HydrophobicContact CG2-CB 4.15Å; V267-E291 HydrophobicContact CG2-CG 3.98Å; V267-V296 HydrophobicContact CG2-CG2 4.12Å; V267-K382 PolarHBondContact N-O 3.01Å; V267-K382 PolarHBondContact O-N 2.89Å; V267-I384 HydrophobicContact CB-CG2 4.33Å; V267-I384 HydrophobicContact CG2-CG2 3.74Å
268L98.6Very high96.2Very high0 Ų030 Ų300%016%0.157CC..EExtended strand (participates in β ladder)trans-108.4122.6175.2-72.9165.4000109V266 N275 V276 F310 W318 L350 F379 I380 M381V266-L268 HydrophobicContact CG2-CG 4.38Å; L268-N275 WeakPolarHBondContact O-CA 3.24Å; L268-V276 HydrophobicContact CB-CB 4.35Å; L268-V276 HydrophobicContact CB-CG2 4.01Å; L268-V276 WeakPolarHBondContact O-CG2 3.47Å; L268-V276 PolarHBondContact O-N 3.25Å; L268-F310 HydrophobicContact CD1-CD1 4.22Å; L268-F310 HydrophobicContact CD1-CE1 3.79Å; L268-F310 HydrophobicContact CD1-CZ 4Å; L268-W318 HydrophobicContact CD1-CH2 3.48Å; L268-W318 VanDerWaalsContact CD1-CH2 3.48Å; L268-W318 HydrophobicContact CD1-CZ2 4.11Å; L268-W318 HydrophobicContact CD1-CZ3 4.1Å; L268-L350 HydrophobicContact CD1-CD1 4.4Å; L268-F379 HydrophobicContact CB-CD1 4.41Å; L268-F379 HydrophobicContact CD2-CB 4.29Å; L268-I380 WeakPolarHBondContact CA-O 3.08Å; L268-M381 HydrophobicContact CD2-CB 3.75Å; L268-M381 HydrophobicContact CD2-CG 3.78Å; L268-M381 HydrophobicContact CD2-SD 3.99Å
269T98.6Very high96.3Very high27 Ų2732.6 Ų32.617%0.16616%0.164CC..EExtended strand (participates in β ladder)trans-104.1122.6172.8-47.80000108.2R274 N275 F379 I380T269-R274 WeakPolarHBondContact CA-O 3.27Å; T269-N275 PolarHBondContact OG1-OD1 2.99Å; T269-F379 CarbonylContact O-C 3.47Å; T269-F379 WeakPolarHBondContact O-CA 3.41Å; T269-I380 PolarHBondContact N-O 2.9Å; T269-I380 PolarHBondContact O-N 2.86Å
270A98.1Very high96.1Very high4 Ų437.6 Ų37.63%0.03319%0.187CC..EExtended strand (participates in β ladder)trans-81.6172.1-178.900000111.9N272 E273 R274 A286 A360 F379A270-N272 PolarHBondContact O-N 2.8Å; A270-E273 WeakPolarHBondContact O-CA 3.25Å; A270-E273 PolarHBondContact O-N 2.83Å; A270-R274 PolarHBondContact N-O 3.04Å; A270-A286 HydrophobicContact CB-CB 3.61Å; A270-A360 HydrophobicContact CB-CB 3.86Å; A270-F379 HydrophobicContact CB-CD1 3.94Å; A270-F379 HydrophobicContact CB-CE1 3.59Å; A270-F379 HydrophobicContact CB-CZ 4.36Å
271G94.4Very high96.1Very high46 Ų4636.8 Ų36.847%0.47420%0.195SC..THydrogen-bonded Turntrans-60.2-7.8177.700000115.9E273 E378G271-E273 VanDerWaalsContact C-N 3.3Å; G271-E378 PolarHBondContact N-O 2.84Å; G271-E378 VanDerWaalsContact N-O 3.12Å
272N96Very high96.2Very high64 Ų6440.7 Ų40.734%0.34221%0.214SC..THydrogen-bonded Turntrans-90.510.6169.672.4-11.8000113.5A270 R274 A286A270-N272 PolarHBondContact O-N 2.8Å; N272-R274 PolarHBondContact O-N 2.91Å; N272-R274 PolarHBondContact OD1-N 2.88Å; N272-R274 VanDerWaalsContact OD1-N 3.16Å; N272-A286 PolarHBondContact ND2-O 3.36Å
273E96.5Very high96.3Very high167 Ų16743.1 Ų43.178%0.7823%0.227SC*.SBendtrans62.520.8179.7-55-178.7167.800114.6A270 G271A270-E273 WeakPolarHBondContact O-CA 3.25Å; A270-E273 PolarHBondContact O-N 2.83Å; G271-E273 VanDerWaalsContact C-N 3.3Å
274R98.1Very high96.4Very high103 Ų10341.4 Ų41.439%0.38922%0.219SC..  trans-112.6147.9176.3-59.9-62.3-177.1152.6-6.8111.8T269 A270 N272 A286 D289T269-R274 WeakPolarHBondContact CA-O 3.27Å; A270-R274 PolarHBondContact N-O 3.04Å; N272-R274 PolarHBondContact O-N 2.91Å; N272-R274 PolarHBondContact OD1-N 2.88Å; N272-R274 VanDerWaalsContact OD1-N 3.16Å; R274-A286 VanDerWaalsContact CB-C 3.46Å; R274-A286 HydrophobicContact CB-CB 4.3Å; R274-A286 WeakPolarHBondContact CB-O 3.21Å; R274-D289 WeakPolarHBondContact CD-OD1 3.5Å; R274-D289 IonicContact CZ-OD1 3.61Å; R274-D289 IonicContact CZ-OD2 3.36Å; R274-D289 IonicContact NE-OD1 3.57Å; R274-D289 IonicContact NH1-OD1 3.38Å; R274-D289 PolarHBondContact NH1-OD1 2.7Å; R274-D289 IonicContact NH1-OD2 2.66Å; R274-D289 PolarHBondContact NH1-OD2 2.6Å
275N98.4Very high96.5Very high13 Ų1341.4 Ų41.47%0.0722%0.219CC..EExtended strand (participates in β ladder)trans-73.7135.3175.6-65.6-18.3000110.7V267 L268 T269 A286 N287 Q288 D289 E290 E295V267-N275 HydrophobicContact CG1-CB 4.02Å; L268-N275 WeakPolarHBondContact O-CA 3.24Å; T269-N275 PolarHBondContact OG1-OD1 2.99Å; N275-A286 WeakPolarHBondContact O-CA 3.43Å; N275-N287 PolarHBondContact O-N 2.84Å; N275-Q288 WeakPolarHBondContact CB-O 3.21Å; N275-Q288 PolarHBondContact N-O 2.9Å; N275-Q288 PolarHBondContact O-N 3.36Å; N275-D289 PolarHBondContact ND2-O 3.28Å; N275-E290 PolarHBondContact ND2-O 2.93Å; N275-E295 HydrophobicContact CB-CG 4.32Å
276V98.5Very high96.6Very high0 Ų041.4 Ų41.40%022%0.219CC..EExtended strand (participates in β ladder)trans-66.2132.4171.9-178.40000109.4L268 L284 A286 E295 F297 W318 L366 F379L268-V276 HydrophobicContact CB-CB 4.35Å; L268-V276 HydrophobicContact CB-CG2 4.01Å; L268-V276 WeakPolarHBondContact O-CG2 3.47Å; L268-V276 PolarHBondContact O-N 3.25Å; V276-L284 HydrophobicContact CG1-CB 4.31Å; V276-L284 HydrophobicContact CG1-CD2 4.17Å; V276-A286 HydrophobicContact CG2-CB 4.2Å; V276-E295 WeakPolarHBondContact O-CA 3.22Å; V276-F297 HydrophobicContact CB-CE2 4.11Å; V276-F297 HydrophobicContact CG1-CE2 4.05Å; V276-F297 HydrophobicContact CG1-CZ 4.11Å; V276-F297 WeakPolarHBondContact O-CE2 3.43Å; V276-W318 HydrophobicContact CB-CH2 4.32Å; V276-W318 HydrophobicContact CB-CZ2 4.39Å; V276-W318 HydrophobicContact CG1-CH2 3.66Å; V276-W318 HydrophobicContact CG1-CZ2 3.56Å; V276-W318 HydrophobicContact CG2-CH2 4.43Å; V276-L366 HydrophobicContact CB-CD1 4.42Å; V276-L366 HydrophobicContact CG1-CD1 3.63Å; V276-L366 HydrophobicContact CG1-CG 4.41Å; V276-L366 HydrophobicContact CG2-CD1 3.83Å; V276-L366 HydrophobicContact CG2-CD2 4.37Å; V276-F379 HydrophobicContact CG2-CE1 4.18Å
277S98.3Very high96.5Very high1 Ų143.1 Ų43.11%0.00723%0.229CC..EExtended strand (participates in β ladder)trans-138154.9-173.4-179.80000112.4R279 S285 Q294 E295S277-R279 WeakPolarHBondContact OG-CB 3.3Å; S277-R279 VanDerWaalsContact OG-CG 3.31Å; S277-R279 WeakPolarHBondContact OG-CG 3.39Å; S277-R279 PolarHBondContact OG-N 2.79Å; S277-S285 PolarHBondContact N-O 3.42Å; S277-S285 PolarHBondContact O-N 3.44Å; S277-Q294 WeakPolarHBondContact CA-O 3.34Å; S277-E295 VanDerWaalsContact CB-OE1 3.25Å; S277-E295 WeakPolarHBondContact CB-OE1 3.25Å; S277-E295 PolarHBondContact OG-OE1 2.7Å
278T97.3Very high96.4Very high24 Ų2445 Ų4515%0.14724%0.237CC..SBendtrans-98.23.3170.355.70000113.4Q280 G281 L284 Q294 F297 T312 C328T278-Q280 VanDerWaalsContact C-N 3.28Å; T278-Q280 PolarHBondContact O-N 2.89Å; T278-G281 PolarHBondContact O-N 3.39Å; T278-L284 HydrophobicContact CG2-CD2 3.74Å; T278-Q294 PolarHBondContact N-O 3.38Å; T278-Q294 WeakPolarHBondContact OG1-CA 3.31Å; T278-Q294 WeakPolarHBondContact OG1-CB 3.37Å; T278-Q294 PolarHBondContact OG1-O 3.36Å; T278-F297 HydrophobicContact CG2-CE1 3.77Å; T278-F297 HydrophobicContact CG2-CZ 4.18Å; T278-T312 HydrophobicContact CG2-CG2 4.01Å; T278-C328 HydrophobicContact CG2-CB 4.14Å
279R94.9Very high96.2Very high81 Ų8150 Ų5031%0.30626%0.264SS..THydrogen-bonded Turntrans-58.7-33.7-176.7-81.7172.3-164.3-149.6-9.6114.5S277 G281 Q288 E290 S292 Q294 E295S277-R279 WeakPolarHBondContact OG-CB 3.3Å; S277-R279 VanDerWaalsContact OG-CG 3.31Å; S277-R279 WeakPolarHBondContact OG-CG 3.39Å; S277-R279 PolarHBondContact OG-N 2.79Å; R279-G281 PolarHBondContact O-N 2.71Å; R279-Q288 VanDerWaalsContact CD-CD 3.45Å; R279-E290 IonicContact CZ-OE2 3.18Å; R279-E290 IonicContact NH1-OE1 3.95Å; R279-E290 IonicContact NH1-OE2 2.79Å; R279-E290 PolarHBondContact NH1-OE2 3.47Å; R279-E290 IonicContact NH2-OE2 2.68Å; R279-E290 PolarHBondContact NH2-OE2 3.07Å; R279-S292 PolarHBondContact NH2-OG 3.02Å; R279-Q294 HydrophobicContact CG-CB 4.18Å; R279-E295 WeakPolarHBondContact CD-OE1 3.46Å; R279-E295 IonicContact CZ-OE1 3.73Å; R279-E295 IonicContact CZ-OE2 3.21Å; R279-E295 IonicContact NE-OE1 2.91Å; R279-E295 PolarHBondContact NE-OE1 2.94Å; R279-E295 IonicContact NE-OE2 3.68Å; R279-E295 IonicContact NH2-OE1 3.97Å; R279-E295 IonicContact NH2-OE2 2.76Å; R279-E295 PolarHBondContact NH2-OE2 2.74Å
280Q90.2Very high96Very high123 Ų12354 Ų5458%0.57528%0.281SS*.THydrogen-bonded Turntrans-83.112.8-175.2-64.7-156.2-1400114T278 N287T278-Q280 VanDerWaalsContact C-N 3.28Å; T278-Q280 PolarHBondContact O-N 2.89Å; Q280-N287 PolarHBondContact NE2-ND2 3.18Å
281G90.7Very high95.9Very high42 Ų4257.9 Ų57.943%0.43330%0.298SS..SBendtrans100.5-125.4175.800000111.8T278 R279T278-G281 PolarHBondContact O-N 3.39Å; R279-G281 PolarHBondContact O-N 2.71Å
282M92.6Very high95.9Very high121 Ų12157.5 Ų57.560%0.59629%0.289SS*.SBendtrans-76.1-37.1-172.3-65.6-172.9-65.400113.3Q327 C328 T329M282-Q327 CarbonylContact O-C 3.5Å; M282-Q327 WeakPolarHBondContact O-CA 3.35Å; M282-Q327 VanDerWaalsContact O-CB 3.27Å; M282-Q327 WeakPolarHBondContact O-CB 3.41Å; M282-C328 PolarHBondContact O-N 3.26Å; M282-T329 HydrophobicContact CB-CG2 3.98Å; M282-T329 HydrophobicContact CG-CG2 3.91Å; M282-T329 HydrophobicContact SD-CG2 4.09Å
283D96.3Very high95.8Very high53 Ų5357.4 Ų57.428%0.28329%0.288SS..BIsolated β-bridgetrans-81.6133.7-177.4-62.4-38.1000110.5Q327 Q365D283-Q327 VanDerWaalsContact OD1-CG 3.24Å; D283-Q327 WeakPolarHBondContact OD1-CG 3.27Å; D283-Q327 PolarHBondContact OD1-NE2 2.67Å; D283-Q365 PolarHBondContact OD2-NE2 2.93Å; D283-Q365 VanDerWaalsContact OD2-NE2 3.16Å
284L97.4Very high95.9Very high0 Ų053.7 Ų53.70%027%0.27CS..  trans-75.1135.1173.1-71.9159000109.7V276 T278 F297 W318 L326 C328 Q365 L366V276-L284 HydrophobicContact CG1-CB 4.31Å; V276-L284 HydrophobicContact CG1-CD2 4.17Å; T278-L284 HydrophobicContact CG2-CD2 3.74Å; L284-F297 HydrophobicContact CD2-CE1 4.14Å; L284-F297 HydrophobicContact CD2-CZ 4.13Å; L284-W318 HydrophobicContact CD1-CB 4.15Å; L284-W318 HydrophobicContact CD1-CD2 3.31Å; L284-W318 VanDerWaalsContact CD1-CE2 3.48Å; L284-W318 HydrophobicContact CD1-CE3 3.84Å; L284-W318 HydrophobicContact CD1-CG 3.45Å; L284-W318 VanDerWaalsContact CD1-CG 3.45Å; L284-W318 HydrophobicContact CD1-CZ2 4.13Å; L284-W318 HydrophobicContact CD1-CZ3 4.43Å; L284-W318 HydrophobicContact CD2-CD2 4.48Å; L284-W318 HydrophobicContact CD2-CZ2 4.07Å; L284-L326 HydrophobicContact CD1-CB 4.03Å; L284-L326 PolarHBondContact N-O 2.85Å; L284-C328 HydrophobicContact CD2-CB 4.24Å; L284-C328 HydrophobicContact CG-CB 4.37Å; L284-Q365 WeakPolarHBondContact O-CA 3.48Å; L284-L366 HydrophobicContact CB-CB 4.37Å; L284-L366 HydrophobicContact CB-CD1 4.13Å; L284-L366 HydrophobicContact CB-CG 4.26Å; L284-L366 PolarHBondContact O-N 2.8Å
285S98.1Very high95.9Very high0 Ų048.8 Ų48.80%025%0.252CS..EExtended strand (participates in β ladder)trans-143.6133-176.7-169.50000112.1S277 N287 G364 Q365S277-S285 PolarHBondContact N-O 3.42Å; S277-S285 PolarHBondContact O-N 3.44Å; S285-N287 WeakPolarHBondContact CB-ND2 3.49Å; S285-N287 PolarHBondContact O-N 3.12Å; S285-N287 PolarHBondContact OG-ND2 2.95Å; S285-G364 CarbonylContact C-O 3.5Å; S285-G364 WeakPolarHBondContact CA-O 3.11Å; S285-G364 PolarHBondContact OG-O 3.43Å; S285-Q365 PolarHBondContact OG-N 3.09Å
286A97.9Very high95.8Very high1 Ų148.2 Ų48.21%0.00825%0.249CC..EExtended strand (participates in β ladder)trans-86.492.2173.200000110A270 N272 R274 N275 V276 A360 G364 L366A270-A286 HydrophobicContact CB-CB 3.61Å; N272-A286 PolarHBondContact ND2-O 3.36Å; R274-A286 VanDerWaalsContact CB-C 3.46Å; R274-A286 HydrophobicContact CB-CB 4.3Å; R274-A286 WeakPolarHBondContact CB-O 3.21Å; N275-A286 WeakPolarHBondContact O-CA 3.43Å; V276-A286 HydrophobicContact CG2-CB 4.2Å; A286-A360 HydrophobicContact CB-CB 4.06Å; A286-G364 PolarHBondContact N-O 2.91Å; A286-G364 WeakPolarHBondContact O-CA 3.42Å; A286-L366 HydrophobicContact CB-CD2 4.33Å
287N96.7Very high95.8Very high36 Ų3648.3 Ų48.319%0.19325%0.249CC..EExtended strand (participates in β ladder)trans-1527.5-173.662.522.6000115N275 Q280 S285N275-N287 PolarHBondContact O-N 2.84Å; Q280-N287 PolarHBondContact NE2-ND2 3.18Å; S285-N287 WeakPolarHBondContact CB-ND2 3.49Å; S285-N287 PolarHBondContact O-N 3.12Å; S285-N287 PolarHBondContact OG-ND2 2.95Å
288Q96.3Very high95.8Very high39 Ų3948.7 Ų48.718%0.18225%0.251CS..EExtended strand (participates in β ladder)trans-112159.5178-57.8-56.7-60.100110.8N275 R279 E295N275-Q288 WeakPolarHBondContact CB-O 3.21Å; N275-Q288 PolarHBondContact N-O 2.9Å; N275-Q288 PolarHBondContact O-N 3.36Å; R279-Q288 VanDerWaalsContact CD-CD 3.45Å; Q288-E295 HydrophobicContact CB-CG 4.08Å; Q288-E295 HydrophobicContact CG-CG 4.32Å
289D95.1Very high95.8Very high105 Ų10547.7 Ų47.756%0.56125%0.245SC*.  trans-109.4-12.5167.3-58.5-29.7000111.9R274 N275R274-D289 WeakPolarHBondContact CD-OD1 3.5Å; R274-D289 IonicContact CZ-OD1 3.61Å; R274-D289 IonicContact CZ-OD2 3.36Å; R274-D289 IonicContact NE-OD1 3.57Å; R274-D289 IonicContact NH1-OD1 3.38Å; R274-D289 PolarHBondContact NH1-OD1 2.7Å; R274-D289 IonicContact NH1-OD2 2.66Å; R274-D289 PolarHBondContact NH1-OD2 2.6Å; N275-D289 PolarHBondContact ND2-O 3.28Å
290E94.4Very high95.8Very high110 Ų11044.8 Ų44.851%0.51424%0.235SC..  trans-79.4161.2-177.6-65.1171.2-164.600111.3N275 R279 E295N275-E290 PolarHBondContact ND2-O 2.93Å; R279-E290 IonicContact CZ-OE2 3.18Å; R279-E290 IonicContact NH1-OE1 3.95Å; R279-E290 IonicContact NH1-OE2 2.79Å; R279-E290 PolarHBondContact NH1-OE2 3.47Å; R279-E290 IonicContact NH2-OE2 2.68Å; R279-E290 PolarHBondContact NH2-OE2 3.07Å; E290-E295 WeakPolarHBondContact O-CG 3.3Å
291E95.3Very high96.1Very high87 Ų8739.4 Ų39.441%0.40721%0.21SC..  trans-122.755.5177-61-175.5-175.100109.7V267 K382V267-E291 HydrophobicContact CG1-CG 4.39Å; V267-E291 HydrophobicContact CG2-CB 4.15Å; V267-E291 HydrophobicContact CG2-CG 3.98Å; E291-K382 IonicContact OE1-NZ 3Å; E291-K382 PolarHBondContact OE1-NZ 3.05Å; E291-K382 IonicContact OE2-NZ 3.04Å; E291-K382 PolarHBondContact OE2-NZ 2.88Å
292S94.7Very high96.1Very high38 Ų3838.2 Ų38.227%0.26620%0.195SC..SBendtrans-82.6176.9175.379.50000111.3R279 Q294 E295 V296R279-S292 PolarHBondContact NH2-OG 3.02Å; S292-Q294 PolarHBondContact O-N 2.94Å; S292-Q294 PolarHBondContact OG-N 3.38Å; S292-E295 WeakPolarHBondContact CB-OE2 3.42Å; S292-E295 PolarHBondContact N-OE2 2.69Å; S292-E295 VanDerWaalsContact N-OE2 3.09Å; S292-E295 PolarHBondContact O-N 2.72Å; S292-E295 PolarHBondContact OG-OE2 2.84Å; S292-V296 WeakPolarHBondContact O-CG2 3.42Å; S292-V296 PolarHBondContact O-N 2.99Å
293D95.1Very high95.9Very high62 Ų6240 Ų4033%0.33220%0.195SC..THydrogen-bonded Turntrans-53.9-20.8175.6-76.5-1.2000113.9R170 W174 A313R170-D293 IonicContact CZ-OD2 3.92Å; R170-D293 VanDerWaalsContact NH2-CG 3.3Å; R170-D293 IonicContact NH2-OD1 3.5Å; R170-D293 PolarHBondContact NH2-OD1 3.18Å; R170-D293 IonicContact NH2-OD2 2.71Å; R170-D293 PolarHBondContact NH2-OD2 2.75Å; W174-D293 PolarHBondContact NE1-O 2.98Å; D293-A313 HydrophobicContact CB-CB 4.17Å
294Q96.8Very high95.5Very high88 Ų8846.3 Ų46.341%0.41122%0.223SC..THydrogen-bonded Turntrans-83.3-14.2178.4-69.3-179.6-35.800114.7S277 T278 R279 S292S277-Q294 WeakPolarHBondContact CA-O 3.34Å; T278-Q294 PolarHBondContact N-O 3.38Å; T278-Q294 WeakPolarHBondContact OG1-CA 3.31Å; T278-Q294 WeakPolarHBondContact OG1-CB 3.37Å; T278-Q294 PolarHBondContact OG1-O 3.36Å; R279-Q294 HydrophobicContact CG-CB 4.18Å; S292-Q294 PolarHBondContact O-N 2.94Å; S292-Q294 PolarHBondContact OG-N 3.38Å
295E98.1Very high95Very high0 Ų049.7 Ų49.70%024%0.241CC..THydrogen-bonded Turntrans-107.4-7.2176-68.473.2-124.100112.2N275 V276 S277 R279 Q288 E290 S292 F297N275-E295 HydrophobicContact CB-CG 4.32Å; V276-E295 WeakPolarHBondContact O-CA 3.22Å; S277-E295 VanDerWaalsContact CB-OE1 3.25Å; S277-E295 WeakPolarHBondContact CB-OE1 3.25Å; S277-E295 PolarHBondContact OG-OE1 2.7Å; R279-E295 WeakPolarHBondContact CD-OE1 3.46Å; R279-E295 IonicContact CZ-OE1 3.73Å; R279-E295 IonicContact CZ-OE2 3.21Å; R279-E295 IonicContact NE-OE1 2.91Å; R279-E295 PolarHBondContact NE-OE1 2.94Å; R279-E295 IonicContact NE-OE2 3.68Å; R279-E295 IonicContact NH2-OE1 3.97Å; R279-E295 IonicContact NH2-OE2 2.76Å; R279-E295 PolarHBondContact NH2-OE2 2.74Å; Q288-E295 HydrophobicContact CB-CG 4.08Å; Q288-E295 HydrophobicContact CG-CG 4.32Å; E290-E295 WeakPolarHBondContact O-CG 3.3Å; S292-E295 WeakPolarHBondContact CB-OE2 3.42Å; S292-E295 PolarHBondContact N-OE2 2.69Å; S292-E295 VanDerWaalsContact N-OE2 3.09Å; S292-E295 PolarHBondContact O-N 2.72Å; S292-E295 PolarHBondContact OG-OE2 2.84Å; E295-F297 WeakPolarHBondContact O-CD2 3.22Å; E295-F297 VanDerWaalsContact O-CE2 3.24Å; E295-F297 WeakPolarHBondContact O-CE2 3.48Å
296V98Very high94.6Very high2 Ų255.3 Ų55.31%0.01226%0.262CS..  trans-94.4129.7178.7175.70000110.3W174 Q265 V267 S292 I384W174-V296 WeakPolarHBondContact CZ2-O 3.38Å; W174-V296 PolarHBondContact NE1-O 2.84Å; Q265-V296 HydrophobicContact CB-CG1 3.71Å; Q265-V296 HydrophobicContact CG-CG1 4.37Å; V267-V296 HydrophobicContact CG2-CG2 4.12Å; S292-V296 WeakPolarHBondContact O-CG2 3.42Å; S292-V296 PolarHBondContact O-N 2.99Å; V296-I384 HydrophobicContact CB-CD1 4.27Å; V296-I384 HydrophobicContact CG1-CD1 3.69Å; V296-I384 HydrophobicContact CG1-CG1 4.17Å; V296-I384 HydrophobicContact CG2-CD1 3.47Å; V296-I384 VanDerWaalsContact CG2-CD1 3.47Å; V296-I384 HydrophobicContact CG2-CG1 4.18Å
297F98.4Very high94.5Very high1 Ų158 Ų580%0.00427%0.273CS..EExtended strand (participates in β ladder)trans-125.8131.2179.1-54.2-73000111.2Q265 V266 V276 T278 L284 E295 F310 R311 T312 W318Q265-F297 CarbonylContact C-O 3.54Å; Q265-F297 WeakPolarHBondContact CA-O 3.44Å; V266-F297 PolarHBondContact N-O 3.31Å; V266-F297 PolarHBondContact O-N 2.9Å; V276-F297 HydrophobicContact CB-CE2 4.11Å; V276-F297 HydrophobicContact CG1-CE2 4.05Å; V276-F297 HydrophobicContact CG1-CZ 4.11Å; V276-F297 WeakPolarHBondContact O-CE2 3.43Å; T278-F297 HydrophobicContact CG2-CE1 3.77Å; T278-F297 HydrophobicContact CG2-CZ 4.18Å; L284-F297 HydrophobicContact CD2-CE1 4.14Å; L284-F297 HydrophobicContact CD2-CZ 4.13Å; E295-F297 WeakPolarHBondContact O-CD2 3.22Å; E295-F297 VanDerWaalsContact O-CE2 3.24Å; E295-F297 WeakPolarHBondContact O-CE2 3.48Å; F297-F310 HydrophobicContact CB-CB 4.24Å; F297-F310 HydrophobicContact CB-CD1 4.16Å; F297-R311 CarbonylContact C-O 3.55Å; F297-R311 VanDerWaalsContact CA-O 3.31Å; F297-R311 WeakPolarHBondContact CA-O 3.5Å; F297-T312 HydrophobicContact CD1-CG2 4.06Å; F297-T312 HydrophobicContact CE1-CG2 4.04Å; F297-W318 AromaticContact CD1-CE2 3.89Å; F297-W318 HydrophobicContact CD1-CZ2 4.1Å; F297-W318 AromaticContact CD1-NE1 3.14Å; F297-W318 AromaticContact CD2-CZ2 3.79Å; F297-W318 HydrophobicContact CD2-CZ2 3.79Å; F297-W318 AromaticContact CE1-CE2 3.9Å; F297-W318 AromaticContact CE1-CZ2 3.99Å; F297-W318 HydrophobicContact CE1-CZ2 3.99Å; F297-W318 AromaticContact CE1-NE1 3.18Å; F297-W318 AromaticContact CE2-CZ2 3.68Å; F297-W318 HydrophobicContact CE2-CZ2 3.68Å; F297-W318 AromaticContact CG-CZ2 3.99Å; F297-W318 HydrophobicContact CG-CZ2 3.99Å; F297-W318 AromaticContact CG-NE1 3.79Å; F297-W318 AromaticContact CZ-CZ2 3.78Å; F297-W318 HydrophobicContact CZ-CZ2 3.78Å; F297-W318 AromaticContact CZ-NE1 3.87Å
298Q98.1Very high94.5Very high10 Ų1056.3 Ų56.35%0.04727%0.265CS..EExtended strand (participates in β ladder)trans-78.6127.9172177.4173.5-70.300110W174 H263 P264 Q265 E300 F310 R311W174-Q298 HydrophobicContact CH2-CB 3.31Å; W174-Q298 HydrophobicContact CZ2-CB 4.04Å; W174-Q298 HydrophobicContact CZ3-CB 3.77Å; H263-Q298 HydrophobicContact CB-CG 3.57Å; P264-Q298 CarbonylContact O-C 3.55Å; P264-Q298 WeakPolarHBondContact O-CA 3.23Å; Q265-Q298 HydrophobicContact CG-CB 4.04Å; Q265-Q298 HydrophobicContact CG-CG 4.47Å; Q298-E300 HydrophobicContact CG-CG 4.25Å; Q298-E300 PolarHBondContact NE2-OE1 3.14Å; Q298-F310 WeakPolarHBondContact O-CA 3.41Å; Q298-R311 HydrophobicContact CB-CB 4.21Å; Q298-R311 PolarHBondContact N-O 2.9Å; Q298-R311 PolarHBondContact O-N 2.86Å
299V97Very high94.6Very high2 Ų254.5 Ų54.51%0.01226%0.256CS..EExtended strand (participates in β ladder)trans-89.9122.7177.2-173.20000109.4P264 V266 I301 C308 F310 M381P264-V299 HydrophobicContact CG-CB 3.87Å; P264-V299 VanDerWaalsContact CG-O 3.29Å; P264-V299 WeakPolarHBondContact CG-O 3.5Å; P264-V299 PolarHBondContact O-N 2.69Å; V266-V299 HydrophobicContact CB-CG2 4.21Å; V266-V299 HydrophobicContact CG1-CG2 3.7Å; V266-V299 HydrophobicContact CG2-CG2 3.45Å; V266-V299 VanDerWaalsContact CG2-CG2 3.45Å; V299-I301 HydrophobicContact CG1-CD1 3.92Å; V299-C308 HydrophobicContact CG1-CB 4.15Å; V299-F310 HydrophobicContact CG2-CD1 4.08Å; V299-F310 HydrophobicContact CG2-CE1 3.84Å; V299-M381 HydrophobicContact CG2-SD 4.42Å
300E95.6Very high94.7Very high20 Ų2049.5 Ų49.59%0.09323%0.229CC..EExtended strand (participates in β ladder)trans-120.1105.1177.4-65.3-176.9-167.200110Q298 A309 R311 Y317 K333Q298-E300 HydrophobicContact CG-CG 4.25Å; Q298-E300 PolarHBondContact NE2-OE1 3.14Å; E300-A309 PolarHBondContact N-O 3.05Å; E300-A309 PolarHBondContact O-N 3.14Å; E300-R311 WeakPolarHBondContact OE1-CD 3.34Å; E300-R311 IonicContact OE1-NH1 2.95Å; E300-Y317 PolarHBondContact OE2-OH 2.57Å; E300-K333 IonicContact OE2-NZ 3.54Å; E300-K333 PolarHBondContact OE2-NZ 2.95Å
301I94.7Very high94.9Very high10 Ų1048.5 Ų48.55%0.05122%0.221CC..EExtended strand (participates in β ladder)trans-80.7126.2175.3-53.6-56.5000109.7V299 C308 F458V299-I301 HydrophobicContact CG1-CD1 3.92Å; I301-C308 HydrophobicContact CD1-CB 3.55Å; I301-F458 HydrophobicContact CD1-CB 4.23Å; I301-F458 HydrophobicContact CG1-CB 4.28Å
302C91.7Very high95Very high17 Ų1744.7 Ų44.712%0.11520%0.203CC..  trans-70.3132174.8-178.70000110.9E304 N305 R306 K307 Y338C302-E304 VanDerWaalsContact C-N 3.29Å; C302-E304 PolarHBondContact O-N 2.89Å; C302-N305 WeakPolarHBondContact CB-OD1 3.41Å; C302-N305 PolarHBondContact SG-OD1 3.04Å; C302-N305 VanDerWaalsContact SG-OD1 3.39Å; C302-R306 VanDerWaalsContact O-CA 3.26Å; C302-R306 WeakPolarHBondContact O-CA 3.42Å; C302-R306 PolarHBondContact O-N 2.82Å; C302-K307 PolarHBondContact N-O 3.15Å; C302-Y338 HydrophobicContact CB-CD1 4.42Å; C302-Y338 HydrophobicContact CB-CE1 3.76Å
303R87.8Confident95Very high158 Ų15844 Ų4460%0.59620%0.2SC*.THydrogen-bonded Turntrans-65.5-31.9179-67.8-176.6-179.3-155.75.2113R306 Y461R303-R306 PolarHBondContact O-NH1 3.5Å; R303-Y461 HydrophobicContact CG-CD2 4.48Å; R303-Y461 HydrophobicContact CG-CG 4.11Å
304E87.9Confident95Very high186 Ų18644.9 Ų44.987%0.86922%0.216SC*.THydrogen-bonded Turntrans-82.5-44-172.5-62.5177.4179.200113C302C302-E304 VanDerWaalsContact C-N 3.29Å; C302-E304 PolarHBondContact O-N 2.89Å
305N86.9Confident95Very high71 Ų7141.9 Ų41.938%0.3821%0.209SC..THydrogen-bonded Turntrans-121.53-17167.317.4000114.2C302 K307C302-N305 WeakPolarHBondContact CB-OD1 3.41Å; C302-N305 PolarHBondContact SG-OD1 3.04Å; C302-N305 VanDerWaalsContact SG-OD1 3.39Å; N305-K307 HydrophobicContact CB-CG 4.38Å; N305-K307 PolarHBondContact O-N 3.37Å; N305-K307 WeakPolarHBondContact OD1-CB 3.47Å; N305-K307 WeakPolarHBondContact OD1-CG 3.27Å; N305-K307 PolarHBondContact OD1-N 2.96Å
306R91.1Very high94.9Very high118 Ų11845.4 Ų45.445%0.44522%0.224SC..  trans58.810.8179.8-51.1-53.2-166.5-177.715.2115.8C302 R303 D460C302-R306 VanDerWaalsContact O-CA 3.26Å; C302-R306 WeakPolarHBondContact O-CA 3.42Å; C302-R306 PolarHBondContact O-N 2.82Å; R303-R306 PolarHBondContact O-NH1 3.5Å; R306-D460 IonicContact CZ-OD1 2.99Å; R306-D460 IonicContact CZ-OD2 2.73Å; R306-D460 VanDerWaalsContact CZ-OD2 3.29Å; R306-D460 IonicContact NH1-OD1 3.83Å; R306-D460 PolarHBondContact NH1-OD1 2.93Å; R306-D460 IonicContact NH1-OD2 2.87Å; R306-D460 PolarHBondContact NH1-OD2 2.81Å; R306-D460 VanDerWaalsContact NH2-CG 3.27Å; R306-D460 IonicContact NH2-OD1 3.79Å; R306-D460 IonicContact NH2-OD2 2.69Å; R306-D460 PolarHBondContact NH2-OD2 3.4Å
307K94.9Very high94.9Very high58 Ų5846.4 Ų46.425%0.25223%0.228SC..  trans-77.1149.8175.6-57.6-166.8-178.8-132.40111.1C302 N305 Y338 D340C302-K307 PolarHBondContact N-O 3.15Å; N305-K307 HydrophobicContact CB-CG 4.38Å; N305-K307 PolarHBondContact O-N 3.37Å; N305-K307 WeakPolarHBondContact OD1-CB 3.47Å; N305-K307 WeakPolarHBondContact OD1-CG 3.27Å; N305-K307 PolarHBondContact OD1-N 2.96Å; K307-Y338 HydrophobicContact CB-CD1 3.92Å; K307-Y338 HydrophobicContact CB-CG 4.15Å; K307-D340 WeakPolarHBondContact CD-OD1 3.18Å; K307-D340 WeakPolarHBondContact CE-OD1 3.34Å; K307-D340 WeakPolarHBondContact CG-OD1 3.26Å; K307-D340 VanDerWaalsContact NZ-CG 3.27Å; K307-D340 IonicContact NZ-OD1 2.76Å; K307-D340 PolarHBondContact NZ-OD1 2.81Å; K307-D340 IonicContact NZ-OD2 2.66Å; K307-D340 PolarHBondContact NZ-OD2 2.84Å
308C96.4Very high94.9Very high1 Ų146.3 Ų46.31%0.00723%0.227CC..EExtended strand (participates in β ladder)trans-95.3143.117973.10000111.7V299 I301 F310 Y338 F339 I341V299-C308 HydrophobicContact CG1-CB 4.15Å; I301-C308 HydrophobicContact CD1-CB 3.55Å; C308-F310 WeakPolarHBondContact SG-CE2 3.4Å; C308-Y338 WeakPolarHBondContact O-CA 3.24Å; C308-F339 PolarHBondContact N-O 3.39Å; C308-F339 PolarHBondContact O-N 3.09Å; C308-F339 PolarHBondContact SG-O 3.21Å; C308-F339 VanDerWaalsContact SG-O 3.37Å; C308-I341 HydrophobicContact CB-CD1 3.71Å; C308-I341 HydrophobicContact CB-CG1 4.04Å; C308-I341 VanDerWaalsContact SG-CD1 3.59Å; C308-I341 WeakPolarHBondContact SG-CG1 3.26Å
309A97.7Very high95Very high0 Ų046.6 Ų46.60%023%0.23CC..EExtended strand (participates in β ladder)trans-114.6148161.800000109.3E300 Y317 K333 C337 Y338E300-A309 PolarHBondContact N-O 3.05Å; E300-A309 PolarHBondContact O-N 3.14Å; A309-Y317 HydrophobicContact CB-CD1 4.13Å; A309-Y317 HydrophobicContact CB-CE1 4.49Å; A309-K333 HydrophobicContact CB-CD 3.79Å; A309-K333 HydrophobicContact CB-CG 4.32Å; A309-C337 WeakPolarHBondContact CA-O 3.23Å; A309-Y338 HydrophobicContact CB-CD1 4.21Å; A309-Y338 HydrophobicContact CB-CE1 4.12Å
310F98.3Very high95Very high1 Ų147.1 Ų47.10%0.00423%0.232CC..EExtended strand (participates in β ladder)trans-111117.2176.1-62.7-81.1000109.2V266 L268 F297 Q298 V299 C308 Y317 W318 F339 L350V266-F310 HydrophobicContact CG2-CE1 4.34Å; L268-F310 HydrophobicContact CD1-CD1 4.22Å; L268-F310 HydrophobicContact CD1-CE1 3.79Å; L268-F310 HydrophobicContact CD1-CZ 4Å; F297-F310 HydrophobicContact CB-CB 4.24Å; F297-F310 HydrophobicContact CB-CD1 4.16Å; Q298-F310 WeakPolarHBondContact O-CA 3.41Å; V299-F310 HydrophobicContact CG2-CD1 4.08Å; V299-F310 HydrophobicContact CG2-CE1 3.84Å; C308-F310 WeakPolarHBondContact SG-CE2 3.4Å; F310-Y317 VanDerWaalsContact O-CA 3.3Å; F310-Y317 WeakPolarHBondContact O-CA 3.44Å; F310-W318 HydrophobicContact CB-CB 4.11Å; F310-W318 HydrophobicContact CB-CD2 3.69Å; F310-W318 HydrophobicContact CB-CE3 4.33Å; F310-W318 HydrophobicContact CB-CG 3.57Å; F310-W318 AromaticContact CD2-CD2 3.99Å; F310-W318 HydrophobicContact CD2-CD2 3.99Å; F310-W318 AromaticContact CD2-CE3 3.74Å; F310-W318 HydrophobicContact CD2-CE3 3.74Å; F310-W318 HydrophobicContact CD2-CG 4.41Å; F310-W318 HydrophobicContact CD2-CZ3 4.2Å; F310-W318 HydrophobicContact CE2-CE3 4.39Å; F310-W318 HydrophobicContact CE2-CZ3 4.49Å; F310-W318 HydrophobicContact CG-CD2 4.06Å; F310-W318 HydrophobicContact CG-CE3 4.22Å; F310-W318 HydrophobicContact CG-CG 4.38Å; F310-W318 PolarHBondContact O-N 3.01Å; F310-F339 HydrophobicContact CD2-CD2 4.05Å; F310-F339 HydrophobicContact CD2-CE2 4.34Å; F310-F339 HydrophobicContact CE2-CD2 4.18Å; F310-L350 HydrophobicContact CE2-CD1 4.02Å; F310-L350 HydrophobicContact CE2-CD2 4.12Å; F310-L350 HydrophobicContact CZ-CD1 4.2Å; F310-L350 HydrophobicContact CZ-CD2 4.05Å
311R98.1Very high95.1Very high88 Ų8847.6 Ų47.633%0.33224%0.237SC..EExtended strand (participates in β ladder)trans-97.7147.2176-174.1179.7178.4175-3.1109.8W174 F297 Q298 E300 K316 Y317W174-R311 HydrophobicContact CH2-CB 4.21Å; W174-R311 HydrophobicContact CH2-CG 4.18Å; W174-R311 WeakPolarHBondContact CH2-O 3.41Å; W174-R311 WeakPolarHBondContact CZ2-O 3.2Å; F297-R311 CarbonylContact C-O 3.55Å; F297-R311 VanDerWaalsContact CA-O 3.31Å; F297-R311 WeakPolarHBondContact CA-O 3.5Å; Q298-R311 HydrophobicContact CB-CB 4.21Å; Q298-R311 PolarHBondContact N-O 2.9Å; Q298-R311 PolarHBondContact O-N 2.86Å; E300-R311 WeakPolarHBondContact OE1-CD 3.34Å; E300-R311 IonicContact OE1-NH1 2.95Å; R311-K316 CarbonylContact C-O 3.54Å; R311-K316 WeakPolarHBondContact CA-O 3.49Å; R311-Y317 HydrophobicContact CB-CD1 3.89Å; R311-Y317 HydrophobicContact CB-CE1 3.62Å; R311-Y317 HydrophobicContact CG-CD1 4.38Å; R311-Y317 HydrophobicContact CG-CE1 3.97Å; R311-Y317 HydrophobicContact CG-CE2 4.47Å
312T97.6Very high95.2Very high7 Ų752.8 Ų52.84%0.04328%0.281CS..  trans-102.3163.8176.472.10000111.5W174 T278 F297 A314 G315 K316 C328W174-T312 WeakPolarHBondContact CH2-O 3.22Å; T278-T312 HydrophobicContact CG2-CG2 4.01Å; F297-T312 HydrophobicContact CD1-CG2 4.06Å; F297-T312 HydrophobicContact CE1-CG2 4.04Å; T312-A314 PolarHBondContact O-N 3.11Å; T312-A314 VanDerWaalsContact O-N 3.16Å; T312-A314 PolarHBondContact OG1-N 3.25Å; T312-G315 WeakPolarHBondContact O-CA 3.39Å; T312-G315 PolarHBondContact O-N 3.25Å; T312-K316 PolarHBondContact N-O 2.88Å; T312-K316 PolarHBondContact OG1-N 3.36Å; T312-K316 PolarHBondContact OG1-O 2.96Å; T312-C328 HydrophobicContact CG2-CB 3.97Å
313A95.4Very high95.3Very high24 Ų2458.2 Ų58.220%0.19831%0.309CS..THydrogen-bonded Turntrans-55.9-31.1174.400000112.9W174 D293 G315W174-A313 HydrophobicContact CB-CB 4.41Å; W174-A313 HydrophobicContact CD2-CB 3.9Å; W174-A313 HydrophobicContact CG-CB 3.75Å; W174-A313 VanDerWaalsContact CZ2-N 3.29Å; D293-A313 HydrophobicContact CB-CB 4.17Å; A313-G315 PolarHBondContact O-N 2.86Å
314A95.1Very high95.8Very high81 Ų8151 Ų5167%0.66928%0.284SS*.THydrogen-bonded Turntrans-75.94.917600000113.9T312 K316T312-A314 PolarHBondContact O-N 3.11Å; T312-A314 VanDerWaalsContact O-N 3.16Å; T312-A314 PolarHBondContact OG1-N 3.25Å; A314-K316 VanDerWaalsContact C-N 3.28Å; A314-K316 PolarHBondContact O-N 3.4Å
315G95.4Very high96.2Very high24 Ų2442.5 Ų42.525%0.24725%0.246CC..SBendtrans72.218.8-179.400000114.1T312 A313T312-G315 WeakPolarHBondContact O-CA 3.39Å; T312-G315 PolarHBondContact O-N 3.25Å; A313-G315 PolarHBondContact O-N 2.86Å
316K97.4Very high96.8Very high75 Ų7539.2 Ų39.233%0.32623%0.228SC..  trans-98.1159.8175-55.7-60.4178.31770110.6R311 T312 A314 C328 A330 S331R311-K316 CarbonylContact C-O 3.54Å; R311-K316 WeakPolarHBondContact CA-O 3.49Å; T312-K316 PolarHBondContact N-O 2.88Å; T312-K316 PolarHBondContact OG1-N 3.36Å; T312-K316 PolarHBondContact OG1-O 2.96Å; A314-K316 VanDerWaalsContact C-N 3.28Å; A314-K316 PolarHBondContact O-N 3.4Å; K316-C328 WeakPolarHBondContact CB-O 3.38Å; K316-A330 CarbonylContact C-O 3.48Å; K316-A330 VanDerWaalsContact CA-O 3.24Å; K316-A330 WeakPolarHBondContact CA-O 3.41Å; K316-S331 PolarHBondContact NZ-OG 3.08Å
317Y98.4Very high97.1Very high22 Ų2235.5 Ų35.59%0.08622%0.216CC..EExtended strand (participates in β ladder)trans-110.4148.9175.3-65.6-92000110.8E300 A309 F310 R311 A330 K333E300-Y317 PolarHBondContact OE2-OH 2.57Å; A309-Y317 HydrophobicContact CB-CD1 4.13Å; A309-Y317 HydrophobicContact CB-CE1 4.49Å; F310-Y317 VanDerWaalsContact O-CA 3.3Å; F310-Y317 WeakPolarHBondContact O-CA 3.44Å; R311-Y317 HydrophobicContact CB-CD1 3.89Å; R311-Y317 HydrophobicContact CB-CE1 3.62Å; R311-Y317 HydrophobicContact CG-CD1 4.38Å; R311-Y317 HydrophobicContact CG-CE1 3.97Å; R311-Y317 HydrophobicContact CG-CE2 4.47Å; Y317-A330 PolarHBondContact N-O 2.79Å; Y317-A330 PolarHBondContact O-N 2.74Å; Y317-K333 HydrophobicContact CD1-CD 4.15Å; Y317-K333 HydrophobicContact CD1-CG 3.75Å; Y317-K333 HydrophobicContact CD2-CG 4.21Å; Y317-K333 HydrophobicContact CE1-CD 3.71Å; Y317-K333 HydrophobicContact CE1-CG 3.64Å; Y317-K333 HydrophobicContact CE2-CG 4.14Å; Y317-K333 HydrophobicContact CG-CG 4.02Å
318W98.4Very high97.1Very high0 Ų033.5 Ų33.50%021%0.209CC..EExtended strand (participates in β ladder)trans-55.9138.4162.6-72.430.3000109.1L268 V276 L284 F297 F310 L326 Q327 C337 F339 L350 L366L268-W318 HydrophobicContact CD1-CH2 3.48Å; L268-W318 VanDerWaalsContact CD1-CH2 3.48Å; L268-W318 HydrophobicContact CD1-CZ2 4.11Å; L268-W318 HydrophobicContact CD1-CZ3 4.1Å; V276-W318 HydrophobicContact CB-CH2 4.32Å; V276-W318 HydrophobicContact CB-CZ2 4.39Å; V276-W318 HydrophobicContact CG1-CH2 3.66Å; V276-W318 HydrophobicContact CG1-CZ2 3.56Å; V276-W318 HydrophobicContact CG2-CH2 4.43Å; L284-W318 HydrophobicContact CD1-CB 4.15Å; L284-W318 HydrophobicContact CD1-CD2 3.31Å; L284-W318 VanDerWaalsContact CD1-CE2 3.48Å; L284-W318 HydrophobicContact CD1-CE3 3.84Å; L284-W318 HydrophobicContact CD1-CG 3.45Å; L284-W318 VanDerWaalsContact CD1-CG 3.45Å; L284-W318 HydrophobicContact CD1-CZ2 4.13Å; L284-W318 HydrophobicContact CD1-CZ3 4.43Å; L284-W318 HydrophobicContact CD2-CD2 4.48Å; L284-W318 HydrophobicContact CD2-CZ2 4.07Å; F297-W318 AromaticContact CD1-CE2 3.89Å; F297-W318 HydrophobicContact CD1-CZ2 4.1Å; F297-W318 AromaticContact CD1-NE1 3.14Å; F297-W318 AromaticContact CD2-CZ2 3.79Å; F297-W318 HydrophobicContact CD2-CZ2 3.79Å; F297-W318 AromaticContact CE1-CE2 3.9Å; F297-W318 AromaticContact CE1-CZ2 3.99Å; F297-W318 HydrophobicContact CE1-CZ2 3.99Å; F297-W318 AromaticContact CE1-NE1 3.18Å; F297-W318 AromaticContact CE2-CZ2 3.68Å; F297-W318 HydrophobicContact CE2-CZ2 3.68Å; F297-W318 AromaticContact CG-CZ2 3.99Å; F297-W318 HydrophobicContact CG-CZ2 3.99Å; F297-W318 AromaticContact CG-NE1 3.79Å; F297-W318 AromaticContact CZ-CZ2 3.78Å; F297-W318 HydrophobicContact CZ-CZ2 3.78Å; F297-W318 AromaticContact CZ-NE1 3.87Å; F310-W318 HydrophobicContact CB-CB 4.11Å; F310-W318 HydrophobicContact CB-CD2 3.69Å; F310-W318 HydrophobicContact CB-CE3 4.33Å; F310-W318 HydrophobicContact CB-CG 3.57Å; F310-W318 AromaticContact CD2-CD2 3.99Å; F310-W318 HydrophobicContact CD2-CD2 3.99Å; F310-W318 AromaticContact CD2-CE3 3.74Å; F310-W318 HydrophobicContact CD2-CE3 3.74Å; F310-W318 HydrophobicContact CD2-CG 4.41Å; F310-W318 HydrophobicContact CD2-CZ3 4.2Å; F310-W318 HydrophobicContact CE2-CE3 4.39Å; F310-W318 HydrophobicContact CE2-CZ3 4.49Å; F310-W318 HydrophobicContact CG-CD2 4.06Å; F310-W318 HydrophobicContact CG-CE3 4.22Å; F310-W318 HydrophobicContact CG-CG 4.38Å; F310-W318 PolarHBondContact O-N 3.01Å; W318-L326 HydrophobicContact CE3-CD1 4.25Å; W318-L326 HydrophobicContact CZ3-CD1 4.44Å; W318-Q327 CarbonylContact C-O 3.47Å; W318-Q327 VanDerWaalsContact CA-O 3.3Å; W318-Q327 WeakPolarHBondContact CA-O 3.47Å; W318-C337 VanDerWaalsContact O-CA 3.24Å; W318-C337 WeakPolarHBondContact O-CA 3.27Å; W318-C337 WeakPolarHBondContact O-CB 3.43Å; W318-C337 PolarHBondContact O-SG 3.49Å; W318-C337 VanDerWaalsContact O-SG 3.39Å; W318-F339 HydrophobicContact CB-CE2 3.87Å; W318-F339 HydrophobicContact CB-CZ 4.14Å; W318-F339 HydrophobicContact CE3-CE2 4.5Å; W318-F339 HydrophobicContact CE3-CZ 4.39Å; W318-L350 HydrophobicContact CZ3-CD1 4.29Å; W318-L366 HydrophobicContact CH2-CD1 3.91Å; W318-L366 HydrophobicContact CZ3-CD1 3.98Å
319T98.5Very high97.1Very high16 Ų1636.1 Ų36.110%0.09823%0.225CC..EExtended strand (participates in β ladder)trans-146.6136.4178.3-173.30000111Q327 A330 N336T319-Q327 HydrophobicContact CG2-CB 4.32Å; T319-Q327 PolarHBondContact N-O 3.39Å; T319-Q327 PolarHBondContact O-N 3.3Å; T319-A330 HydrophobicContact CG2-CB 4.09Å; T319-N336 WeakPolarHBondContact CA-O 3.45Å
320L98.6Very high97Very high12 Ų1236.9 Ų36.96%0.06323%0.232CC..EExtended strand (participates in β ladder)trans-70135.3167.9-177.867000110.4L326 N336 A352 A353 N354 A368L320-L326 HydrophobicContact CB-CD2 4.14Å; L320-L326 HydrophobicContact CD1-CD2 3.8Å; L320-N336 HydrophobicContact CB-CB 4.15Å; L320-N336 PolarHBondContact N-O 2.84Å; L320-A352 HydrophobicContact CD1-CB 4.31Å; L320-A352 HydrophobicContact CD2-CB 4.1Å; L320-A353 HydrophobicContact CD2-CB 4.32Å; L320-N354 HydrophobicContact CD2-CB 3.71Å; L320-A368 HydrophobicContact CD1-CB 3.84Å
321T97.9Very high96.9Very high31 Ų3140.8 Ų40.819%0.1926%0.259CS..  trans-102.6164.6174.266.10000111.4N323 G324 G325 Q327T321-N323 PolarHBondContact O-N 2.88Å; T321-N323 VanDerWaalsContact O-N 3.16Å; T321-N323 PolarHBondContact OG1-OD1 2.82Å; T321-G324 PolarHBondContact O-N 2.97Å; T321-G325 WeakPolarHBondContact CB-O 3.38Å; T321-G325 PolarHBondContact N-O 2.78Å; T321-G325 PolarHBondContact OG1-N 3.28Å; T321-G325 PolarHBondContact OG1-O 2.74Å; T321-Q327 HydrophobicContact CG2-CB 4.13Å; T321-Q327 HydrophobicContact CG2-CG 3.71Å
322A95.9Very high96.8Very high119 Ų11940.8 Ų40.898%0.98327%0.273SS*.THydrogen-bonded Turntrans-61-25.1-176.600000114.4G324A322-G324 VanDerWaalsContact C-N 3.31Å
323N94.4Very high96.7Very high131 Ų13144.5 Ų44.570%0.70129%0.288SS*.THydrogen-bonded Turntrans-89.85.9177.571.510.3000113.3T321 G325T321-N323 PolarHBondContact O-N 2.88Å; T321-N323 VanDerWaalsContact O-N 3.16Å; T321-N323 PolarHBondContact OG1-OD1 2.82Å; N323-G325 PolarHBondContact OD1-N 2.73Å
324G96.8Very high96.7Very high7 Ų745.9 Ų45.97%0.07230%0.297CS..SBendtrans86.3-6.2-177.400000115.1T321 A322 A367 A368T321-G324 PolarHBondContact O-N 2.97Å; A322-G324 VanDerWaalsContact C-N 3.31Å; G324-A367 CarbonylContact O-C 3.46Å; G324-A367 VanDerWaalsContact O-CA 3.26Å; G324-A367 WeakPolarHBondContact O-CA 3.19Å; G324-A367 WeakPolarHBondContact O-CB 3.31Å; G324-A368 PolarHBondContact O-N 3.43Å
325G97.9Very high96.7Very high7 Ų747.3 Ų47.37%0.07230%0.297CS..BIsolated β-bridgetrans-71.8152.7176.100000112.6T321 N323T321-G325 WeakPolarHBondContact CB-O 3.38Å; T321-G325 PolarHBondContact N-O 2.78Å; T321-G325 PolarHBondContact OG1-N 3.28Å; T321-G325 PolarHBondContact OG1-O 2.74Å; N323-G325 PolarHBondContact OD1-N 2.73Å
326L98.3Very high96.8Very high1 Ų149.6 Ų49.61%0.00530%0.304CS..EExtended strand (participates in β ladder)trans-102.7132.7173.2-60.4-170.4000111.9L284 W318 L320 F339 V358 L366L284-L326 HydrophobicContact CD1-CB 4.03Å; L284-L326 PolarHBondContact N-O 2.85Å; W318-L326 HydrophobicContact CE3-CD1 4.25Å; W318-L326 HydrophobicContact CZ3-CD1 4.44Å; L320-L326 HydrophobicContact CB-CD2 4.14Å; L320-L326 HydrophobicContact CD1-CD2 3.8Å; L326-F339 HydrophobicContact CD1-CE1 3.84Å; L326-F339 HydrophobicContact CD1-CZ 4.15Å; L326-F339 HydrophobicContact CD2-CE1 3.83Å; L326-F339 HydrophobicContact CD2-CZ 4.01Å; L326-V358 HydrophobicContact CD1-CB 4.37Å; L326-V358 HydrophobicContact CD1-CG1 3.52Å; L326-V358 HydrophobicContact CD1-CG2 3.84Å; L326-V358 HydrophobicContact CG-CG1 4.47Å; L326-L366 HydrophobicContact CB-CB 4.13Å; L326-L366 HydrophobicContact CD1-CB 4.13Å; L326-L366 HydrophobicContact CD1-CD1 4.45Å; L326-L366 HydrophobicContact CG-CB 4.33Å; L326-L366 PolarHBondContact N-O 2.89Å
327Q97.6Very high96.9Very high40 Ų4046 Ų4619%0.18729%0.288CS..EExtended strand (participates in β ladder)trans-127.9163.2179.3-70.1-173.8-16.500111.9M282 D283 W318 T319 T321 T329M282-Q327 CarbonylContact O-C 3.5Å; M282-Q327 WeakPolarHBondContact O-CA 3.35Å; M282-Q327 VanDerWaalsContact O-CB 3.27Å; M282-Q327 WeakPolarHBondContact O-CB 3.41Å; D283-Q327 VanDerWaalsContact OD1-CG 3.24Å; D283-Q327 WeakPolarHBondContact OD1-CG 3.27Å; D283-Q327 PolarHBondContact OD1-NE2 2.67Å; W318-Q327 CarbonylContact C-O 3.47Å; W318-Q327 VanDerWaalsContact CA-O 3.3Å; W318-Q327 WeakPolarHBondContact CA-O 3.47Å; T319-Q327 HydrophobicContact CG2-CB 4.32Å; T319-Q327 PolarHBondContact N-O 3.39Å; T319-Q327 PolarHBondContact O-N 3.3Å; T321-Q327 HydrophobicContact CG2-CB 4.13Å; T321-Q327 HydrophobicContact CG2-CG 3.71Å; Q327-T329 HydrophobicContact CB-CG2 4.26Å
328C94.8Very high96.8Very high16 Ų1646.9 Ų46.911%0.10829%0.292CS..EExtended strand (participates in β ladder)trans-112.254.3175.662.10000112.6T278 M282 L284 T312 K316T278-C328 HydrophobicContact CG2-CB 4.14Å; M282-C328 PolarHBondContact O-N 3.26Å; L284-C328 HydrophobicContact CD2-CB 4.24Å; L284-C328 HydrophobicContact CG-CB 4.37Å; T312-C328 HydrophobicContact CG2-CB 3.97Å; K316-C328 WeakPolarHBondContact CB-O 3.38Å
329T96.4Very high96.8Very high56 Ų5646.9 Ų46.934%0.34429%0.292SS..EExtended strand (participates in β ladder)trans-112.7-17-171.753.70000114.4M282 Q327 S331M282-T329 HydrophobicContact CB-CG2 3.98Å; M282-T329 HydrophobicContact CG-CG2 3.91Å; M282-T329 HydrophobicContact SD-CG2 4.09Å; Q327-T329 HydrophobicContact CB-CG2 4.26Å; T329-S331 PolarHBondContact O-N 2.8Å
330A96.6Very high96.8Very high17 Ų1748.5 Ų48.514%0.1430%0.3CS..EExtended strand (participates in β ladder)trans-69.5128.5-175.200000111.5K316 Y317 T319 C337K316-A330 CarbonylContact C-O 3.48Å; K316-A330 VanDerWaalsContact CA-O 3.24Å; K316-A330 WeakPolarHBondContact CA-O 3.41Å; Y317-A330 PolarHBondContact N-O 2.79Å; Y317-A330 PolarHBondContact O-N 2.74Å; T319-A330 HydrophobicContact CG2-CB 4.09Å; A330-C337 VanDerWaalsContact CB-SG 3.6Å
331S95.9Very high96.7Very high82 Ų8249.4 Ų49.457%0.57330%0.304SS*.SBendtrans-93.2-15.3179.2-53.30000113K316 T329K316-S331 PolarHBondContact NZ-OG 3.08Å; T329-S331 PolarHBondContact O-N 2.8Å
332S94.8Very high96.6Very high89 Ų8950.8 Ų50.862%0.62231%0.308SS*.SBendtrans-138.2152.1173.554.40000108.7
333K95.6Very high96.6Very high84 Ų8448.2 Ų48.237%0.36527%0.273SS..  trans-68.9133.8178-69.5-179.8-72-162.30110E300 A309 Y317 Y338E300-K333 IonicContact OE2-NZ 3.54Å; E300-K333 PolarHBondContact OE2-NZ 2.95Å; A309-K333 HydrophobicContact CB-CD 3.79Å; A309-K333 HydrophobicContact CB-CG 4.32Å; Y317-K333 HydrophobicContact CD1-CD 4.15Å; Y317-K333 HydrophobicContact CD1-CG 3.75Å; Y317-K333 HydrophobicContact CD2-CG 4.21Å; Y317-K333 HydrophobicContact CE1-CD 3.71Å; Y317-K333 HydrophobicContact CE1-CG 3.64Å; Y317-K333 HydrophobicContact CE2-CG 4.14Å; Y317-K333 HydrophobicContact CG-CG 4.02Å; K333-Y338 HydrophobicContact CB-CE2 4.45Å; K333-Y338 HydrophobicContact CD-CE1 4.38Å
334S95.2Very high96.7Very high54 Ų5446.1 Ų46.138%0.37826%0.256SS..  trans-129.5176.9170.172.40000109.2N336 C337 Y338S334-N336 PolarHBondContact O-N 2.93Å; S334-N336 VanDerWaalsContact O-N 3.13Å; S334-N336 PolarHBondContact OG-N 2.83Å; S334-C337 WeakPolarHBondContact O-CB 3.09Å; S334-C337 PolarHBondContact O-N 2.84Å; S334-Y338 VanDerWaalsContact O-CD2 3.3Å; S334-Y338 WeakPolarHBondContact O-CD2 3.09Å
335T96.1Very high96.5Very high111 Ų11147.4 Ų47.468%0.68127%0.269SS*.G310 helixtrans-52.1-35.9174.7-51.90000112.5C337 Y338 A353T335-C337 PolarHBondContact O-N 3.26Å; T335-Y338 PolarHBondContact O-N 3.45Å; T335-A353 HydrophobicContact CG2-CB 4.29Å; T335-A353 WeakPolarHBondContact O-CB 3.28Å
336N97.9Very high96.5Very high72 Ų7250.4 Ų50.439%0.38528%0.28SS..G310 helixtrans-73.7-10.3179.9-68.9-16.8000114T319 L320 S334T319-N336 WeakPolarHBondContact CA-O 3.45Å; L320-N336 HydrophobicContact CB-CB 4.15Å; L320-N336 PolarHBondContact N-O 2.84Å; S334-N336 PolarHBondContact O-N 2.93Å; S334-N336 VanDerWaalsContact O-N 3.13Å; S334-N336 PolarHBondContact OG-N 2.83Å
337C98.1Very high96.4Very high0 Ų053.4 Ų53.40%029%0.291CS..G310 helixtrans-90.4-6.1176.5-59.10000113.3A309 W318 A330 S334 T335 F339A309-C337 WeakPolarHBondContact CA-O 3.23Å; W318-C337 VanDerWaalsContact O-CA 3.24Å; W318-C337 WeakPolarHBondContact O-CA 3.27Å; W318-C337 WeakPolarHBondContact O-CB 3.43Å; W318-C337 PolarHBondContact O-SG 3.49Å; W318-C337 VanDerWaalsContact O-SG 3.39Å; A330-C337 VanDerWaalsContact CB-SG 3.6Å; S334-C337 WeakPolarHBondContact O-CB 3.09Å; S334-C337 PolarHBondContact O-N 2.84Å; T335-C337 PolarHBondContact O-N 3.26Å; C337-F339 WeakPolarHBondContact O-CD2 3.4Å; C337-F339 WeakPolarHBondContact O-CE2 3.42Å
338Y98.1Very high96.4Very high40 Ų4051.5 Ų51.516%0.15728%0.283CS..  trans-101.3136.5-176.7-72.8-64.1000111.5C302 K307 C308 A309 K333 S334 T335C302-Y338 HydrophobicContact CB-CD1 4.42Å; C302-Y338 HydrophobicContact CB-CE1 3.76Å; K307-Y338 HydrophobicContact CB-CD1 3.92Å; K307-Y338 HydrophobicContact CB-CG 4.15Å; C308-Y338 WeakPolarHBondContact O-CA 3.24Å; A309-Y338 HydrophobicContact CB-CD1 4.21Å; A309-Y338 HydrophobicContact CB-CE1 4.12Å; K333-Y338 HydrophobicContact CB-CE2 4.45Å; K333-Y338 HydrophobicContact CD-CE1 4.38Å; S334-Y338 VanDerWaalsContact O-CD2 3.3Å; S334-Y338 WeakPolarHBondContact O-CD2 3.09Å; T335-Y338 PolarHBondContact O-N 3.45Å
339F98.3Very high96.6Very high0 Ų050.8 Ų50.80%028%0.278CS..BIsolated β-bridgetrans-126.2141.1178.1-54.4-97.5000109.4C308 F310 W318 L326 C337 L350 R351 A352 V358C308-F339 PolarHBondContact N-O 3.39Å; C308-F339 PolarHBondContact O-N 3.09Å; C308-F339 PolarHBondContact SG-O 3.21Å; C308-F339 VanDerWaalsContact SG-O 3.37Å; F310-F339 HydrophobicContact CD2-CD2 4.05Å; F310-F339 HydrophobicContact CD2-CE2 4.34Å; F310-F339 HydrophobicContact CE2-CD2 4.18Å; W318-F339 HydrophobicContact CB-CE2 3.87Å; W318-F339 HydrophobicContact CB-CZ 4.14Å; W318-F339 HydrophobicContact CE3-CE2 4.5Å; W318-F339 HydrophobicContact CE3-CZ 4.39Å; L326-F339 HydrophobicContact CD1-CE1 3.84Å; L326-F339 HydrophobicContact CD1-CZ 4.15Å; L326-F339 HydrophobicContact CD2-CE1 3.83Å; L326-F339 HydrophobicContact CD2-CZ 4.01Å; C337-F339 WeakPolarHBondContact O-CD2 3.4Å; C337-F339 WeakPolarHBondContact O-CE2 3.42Å; F339-L350 HydrophobicContact CB-CD2 4.48Å; F339-R351 CarbonylContact C-O 3.55Å; F339-R351 VanDerWaalsContact CA-O 3.26Å; F339-R351 WeakPolarHBondContact CA-O 3.38Å; F339-A352 HydrophobicContact CD1-CB 3.93Å; F339-A352 HydrophobicContact CE1-CB 3.89Å; F339-V358 HydrophobicContact CD1-CG2 4.21Å; F339-V358 HydrophobicContact CE1-CG2 4.21Å
340D97.6Very high96.7Very high50 Ų5048.1 Ų48.127%0.26726%0.261SS..EExtended strand (participates in β ladder)trans-83.7128.6167.3-56.6-74.5000108.1K307 R351K307-D340 WeakPolarHBondContact CD-OD1 3.18Å; K307-D340 WeakPolarHBondContact CE-OD1 3.34Å; K307-D340 WeakPolarHBondContact CG-OD1 3.26Å; K307-D340 VanDerWaalsContact NZ-CG 3.27Å; K307-D340 IonicContact NZ-OD1 2.76Å; K307-D340 PolarHBondContact NZ-OD1 2.81Å; K307-D340 IonicContact NZ-OD2 2.66Å; K307-D340 PolarHBondContact NZ-OD2 2.84Å; D340-R351 HydrophobicContact CB-CB 4.24Å; D340-R351 PolarHBondContact N-O 2.89Å; D340-R351 PolarHBondContact O-N 3.46Å
341I97.1Very high96.8Very high31 Ų3152 Ų5216%0.15927%0.272CS..EExtended strand (participates in β ladder)trans-94122.3173.2-54.7-179.8000107.9C308 W343 L348 L350C308-I341 HydrophobicContact CB-CD1 3.71Å; C308-I341 HydrophobicContact CB-CG1 4.04Å; C308-I341 VanDerWaalsContact SG-CD1 3.59Å; C308-I341 WeakPolarHBondContact SG-CG1 3.26Å; I341-W343 HydrophobicContact CD1-CZ2 4.31Å; I341-W343 HydrophobicContact CG2-CD2 3.97Å; I341-W343 HydrophobicContact CG2-CE3 4.45Å; I341-W343 HydrophobicContact CG2-CG 4.47Å; I341-W343 HydrophobicContact CG2-CH2 4.33Å; I341-W343 HydrophobicContact CG2-CZ2 3.73Å; I341-L348 HydrophobicContact CG2-CB 3.99Å; I341-L348 HydrophobicContact CG2-CD1 4.33Å; I341-L348 HydrophobicContact CG2-CD2 4.08Å; I341-L348 HydrophobicContact CG2-CG 4.39Å; I341-L350 HydrophobicContact CG1-CD2 3.9Å
342E96.5Very high96.9Very high59 Ų5948.2 Ų48.228%0.27625%0.246SC..EExtended strand (participates in β ladder)trans-108.3113.7170.2-67174.4-161.700109R344 L348 T349 Y357E342-R344 IonicContact OE2-NH2 2.6Å; E342-L348 CarbonylContact O-C 3.48Å; E342-L348 VanDerWaalsContact O-CA 3.24Å; E342-L348 WeakPolarHBondContact O-CA 3.42Å; E342-T349 WeakPolarHBondContact CB-OG1 3.26Å; E342-T349 PolarHBondContact N-O 3.4Å; E342-T349 PolarHBondContact O-N 3.01Å; E342-Y357 VanDerWaalsContact CD-OH 3.26Å; E342-Y357 PolarHBondContact OE1-OH 3.1Å; E342-Y357 WeakPolarHBondContact OE2-CE1 3.2Å; E342-Y357 PolarHBondContact OE2-OH 3.28Å
343W95.6Very high97Very high65 Ų6545.9 Ų45.925%0.24623%0.232CC..EExtended strand (participates in β ladder)trans-78.6125.1-178.8-58.3100.8000111.3I341 L348 M381 F456 E457 F458I341-W343 HydrophobicContact CD1-CZ2 4.31Å; I341-W343 HydrophobicContact CG2-CD2 3.97Å; I341-W343 HydrophobicContact CG2-CE3 4.45Å; I341-W343 HydrophobicContact CG2-CG 4.47Å; I341-W343 HydrophobicContact CG2-CH2 4.33Å; I341-W343 HydrophobicContact CG2-CZ2 3.73Å; W343-L348 HydrophobicContact CE3-CB 4.22Å; W343-L348 HydrophobicContact CE3-CD2 4.41Å; W343-L348 HydrophobicContact CH2-CD2 4.34Å; W343-L348 HydrophobicContact CZ3-CD2 3.96Å; W343-M381 HydrophobicContact CH2-CE 3.17Å; W343-M381 HydrophobicContact CZ2-CE 4.14Å; W343-M381 HydrophobicContact CZ3-CE 3.68Å; W343-F456 VanDerWaalsContact CH2-O 3.23Å; W343-F456 WeakPolarHBondContact CH2-O 3.5Å; W343-F456 WeakPolarHBondContact CZ3-O 3.31Å; W343-E457 HydrophobicContact CB-CG 4.28Å; W343-E457 HydrophobicContact CD2-CB 3.98Å; W343-E457 HydrophobicContact CD2-CG 3.66Å; W343-E457 HydrophobicContact CE3-CG 4.07Å; W343-E457 HydrophobicContact CG-CB 4.21Å; W343-E457 HydrophobicContact CG-CG 3.72Å; W343-E457 VanDerWaalsContact CZ2-CA 3.43Å; W343-E457 HydrophobicContact CZ2-CB 4.09Å; W343-F458 AromaticContact CH2-CD2 3.9Å; W343-F458 HydrophobicContact CH2-CD2 3.9Å; W343-F458 HydrophobicContact CZ2-CB 4.26Å; W343-F458 HydrophobicContact CZ2-CD2 4.37Å
344R94.9Very high97.1Very high87 Ų8745.2 Ų45.233%0.32823%0.233SC..EExtended strand (participates in β ladder)trans-124.568.4-177.7-63.9-169177.7-159-4110.2E342 K346 R347 A373E342-R344 IonicContact OE2-NH2 2.6Å; R344-K346 PolarHBondContact O-N 2.8Å; R344-K346 VanDerWaalsContact O-N 3.11Å; R344-R347 CarbonylContact C-O 3.54Å; R344-R347 WeakPolarHBondContact CA-O 3.39Å; R344-R347 HydrophobicContact CB-CB 4.43Å; R344-R347 PolarHBondContact N-O 2.86Å; R344-R347 PolarHBondContact O-N 2.62Å; R344-A373 PolarHBondContact NH1-O 3.22Å
345G94.2Very high97.3Very high35 Ų3543.7 Ų43.736%0.36123%0.225SC..THydrogen-bonded Turntrans61.3-114.3-174.900000111R347G345-R347 PolarHBondContact O-N 2.89Å
346K96.3Very high97.4Very high70 Ų7041.3 Ų41.330%0.30421%0.206SC..THydrogen-bonded Turntrans-81.22.8178.5-67.8-176.2172.2-159.70114.2R344 D423 G424 A425 D453 L455R344-K346 PolarHBondContact O-N 2.8Å; R344-K346 VanDerWaalsContact O-N 3.11Å; K346-D423 WeakPolarHBondContact CB-O 3.17Å; K346-D423 WeakPolarHBondContact CD-O 3.21Å; K346-G424 WeakPolarHBondContact O-CA 3.46Å; K346-A425 HydrophobicContact CG-CB 4.4Å; K346-D453 VanDerWaalsContact CE-OD2 3.27Å; K346-D453 WeakPolarHBondContact CE-OD2 3.43Å; K346-D453 IonicContact NZ-OD2 2.7Å; K346-D453 PolarHBondContact NZ-OD2 3.19Å; K346-L455 HydrophobicContact CG-CD2 3.97Å
347R97.6Very high97.4Very high63 Ų6339.1 Ų39.124%0.23819%0.192CC..EExtended strand (participates in β ladder)trans-127.4169.6-178.6-58.9-64-178.1-93.81.1109.8R344 G345 E378 F379 I380 D423R344-R347 CarbonylContact C-O 3.54Å; R344-R347 WeakPolarHBondContact CA-O 3.39Å; R344-R347 HydrophobicContact CB-CB 4.43Å; R344-R347 PolarHBondContact N-O 2.86Å; R344-R347 PolarHBondContact O-N 2.62Å; G345-R347 PolarHBondContact O-N 2.89Å; R347-E378 HydrophobicContact CB-CB 4.14Å; R347-E378 HydrophobicContact CB-CG 4.33Å; R347-E378 HydrophobicContact CG-CB 4.37Å; R347-F379 CarbonylContact C-O 3.59Å; R347-F379 WeakPolarHBondContact CA-O 3.4Å; R347-I380 VanDerWaalsContact CD-CG1 3.43Å; R347-I380 VanDerWaalsContact CZ-CD1 3.48Å; R347-I380 VanDerWaalsContact CZ-CG1 3.5Å; R347-D423 IonicContact CZ-OD1 2.66Å; R347-D423 PolarHBondContact NH1-O 3.22Å; R347-D423 VanDerWaalsContact NH1-O 3.15Å; R347-D423 IonicContact NH1-OD1 2.67Å; R347-D423 PolarHBondContact NH1-OD1 3.27Å; R347-D423 IonicContact NH1-OD2 3.8Å; R347-D423 IonicContact NH2-OD1 3.23Å; R347-D423 PolarHBondContact NH2-OD1 3.09Å; R347-D423 IonicContact NH2-OD2 2.7Å
348L97.8Very high97.4Very high1 Ų139.1 Ų39.11%0.00519%0.192CC..EExtended strand (participates in β ladder)trans-139.4160.5167.767.485.8000110.6I341 E342 W343 L350 E378 F379 M381I341-L348 HydrophobicContact CG2-CB 3.99Å; I341-L348 HydrophobicContact CG2-CD1 4.33Å; I341-L348 HydrophobicContact CG2-CD2 4.08Å; I341-L348 HydrophobicContact CG2-CG 4.39Å; E342-L348 CarbonylContact O-C 3.48Å; E342-L348 VanDerWaalsContact O-CA 3.24Å; E342-L348 WeakPolarHBondContact O-CA 3.42Å; W343-L348 HydrophobicContact CE3-CB 4.22Å; W343-L348 HydrophobicContact CE3-CD2 4.41Å; W343-L348 HydrophobicContact CH2-CD2 4.34Å; W343-L348 HydrophobicContact CZ3-CD2 3.96Å; L348-L350 HydrophobicContact CD1-CD1 4.47Å; L348-L350 HydrophobicContact CD1-CD2 3.62Å; L348-L350 HydrophobicContact CD1-CG 3.66Å; L348-E378 CarbonylContact O-C 3.5Å; L348-E378 WeakPolarHBondContact O-CA 3.44Å; L348-F379 HydrophobicContact CD1-CB 3.98Å; L348-F379 HydrophobicContact CG-CB 4.26Å; L348-F379 PolarHBondContact N-O 2.87Å; L348-F379 PolarHBondContact O-N 2.99Å; L348-M381 HydrophobicContact CD2-CB 3.58Å; L348-M381 HydrophobicContact CD2-CE 3.41Å; L348-M381 VanDerWaalsContact CD2-CE 3.41Å; L348-M381 HydrophobicContact CD2-CG 4.34Å; L348-M381 HydrophobicContact CD2-SD 3.9Å
349T98.4Very high97.4Very high0 Ų037.7 Ų37.70%019%0.189CC..EExtended strand (participates in β ladder)trans-120.3144.4168.157.50000109.1E342 A373 E377 E378E342-T349 WeakPolarHBondContact CB-OG1 3.26Å; E342-T349 PolarHBondContact N-O 3.4Å; E342-T349 PolarHBondContact O-N 3.01Å; T349-A373 HydrophobicContact CG2-CB 3.68Å; T349-E377 HydrophobicContact CG2-CB 4.42Å; T349-E378 HydrophobicContact CG2-CG 3.99Å
350L98.4Very high97.4Very high0 Ų038.7 Ų38.70%020%0.197CC..EExtended strand (participates in β ladder)trans-106.2125.8178.1-62.9174.7000109.6L268 F310 W318 F339 I341 L348 Y357 V358L268-L350 HydrophobicContact CD1-CD1 4.4Å; F310-L350 HydrophobicContact CE2-CD1 4.02Å; F310-L350 HydrophobicContact CE2-CD2 4.12Å; F310-L350 HydrophobicContact CZ-CD1 4.2Å; F310-L350 HydrophobicContact CZ-CD2 4.05Å; W318-L350 HydrophobicContact CZ3-CD1 4.29Å; F339-L350 HydrophobicContact CB-CD2 4.48Å; I341-L350 HydrophobicContact CG1-CD2 3.9Å; L348-L350 HydrophobicContact CD1-CD1 4.47Å; L348-L350 HydrophobicContact CD1-CD2 3.62Å; L348-L350 HydrophobicContact CD1-CG 3.66Å; L350-Y357 WeakPolarHBondContact O-CA 3.27Å; L350-V358 HydrophobicContact CB-CB 4.12Å; L350-V358 HydrophobicContact CB-CG2 3.94Å; L350-V358 WeakPolarHBondContact O-CG2 3.34Å; L350-V358 PolarHBondContact O-N 2.67Å
351R98.3Very high97.3Very high99 Ų9940.6 Ų40.637%0.37420%0.203SC..EExtended strand (participates in β ladder)trans-108.7122.5174.2-170.9178.9-178.4-167.9-4.3109.9F339 D340 G355 K356 Y357F339-R351 CarbonylContact C-O 3.55Å; F339-R351 VanDerWaalsContact CA-O 3.26Å; F339-R351 WeakPolarHBondContact CA-O 3.38Å; D340-R351 HydrophobicContact CB-CB 4.24Å; D340-R351 PolarHBondContact N-O 2.89Å; D340-R351 PolarHBondContact O-N 3.46Å; R351-G355 VanDerWaalsContact NE-C 3.34Å; R351-G355 PolarHBondContact NE-O 2.7Å; R351-G355 PolarHBondContact NH2-O 3.33Å; R351-K356 WeakPolarHBondContact CA-O 3.42Å; R351-Y357 HydrophobicContact CB-CD1 4.18Å; R351-Y357 HydrophobicContact CB-CE1 4.14Å
352A98.4Very high97.2Very high2 Ų250.1 Ų50.12%0.01724%0.243CC..  trans-85.4174.3-176.900000112.3L320 F339 N354 G355 K356 V358 A368L320-A352 HydrophobicContact CD1-CB 4.31Å; L320-A352 HydrophobicContact CD2-CB 4.1Å; F339-A352 HydrophobicContact CD1-CB 3.93Å; F339-A352 HydrophobicContact CE1-CB 3.89Å; A352-N354 PolarHBondContact O-N 2.87Å; A352-N354 VanDerWaalsContact O-N 3.1Å; A352-G355 WeakPolarHBondContact O-CA 3.1Å; A352-G355 PolarHBondContact O-N 2.73Å; A352-K356 PolarHBondContact N-O 3.49Å; A352-V358 HydrophobicContact CB-CG2 4.42Å; A352-A368 HydrophobicContact CB-CB 3.53Å
353A97.4Very high97.1Very high41 Ų4151.7 Ų51.734%0.33925%0.254SS..THydrogen-bonded Turntrans-59.2-22.9-177.600000115.3L320 T335 G355L320-A353 HydrophobicContact CD2-CB 4.32Å; T335-A353 HydrophobicContact CG2-CB 4.29Å; T335-A353 WeakPolarHBondContact O-CB 3.28Å; A353-G355 PolarHBondContact O-N 2.69Å
354N97.9Very high97.2Very high69 Ų6948.8 Ų48.837%0.36924%0.243SC..THydrogen-bonded Turntrans-77.93.6172.764.9-5.1000113.4L320 A352 K356 A368L320-N354 HydrophobicContact CD2-CB 3.71Å; A352-N354 PolarHBondContact O-N 2.87Å; A352-N354 VanDerWaalsContact O-N 3.1Å; N354-K356 VanDerWaalsContact C-N 3.27Å; N354-K356 PolarHBondContact O-N 3.34Å; N354-K356 WeakPolarHBondContact OD1-CB 3.42Å; N354-K356 PolarHBondContact OD1-N 3.46Å; N354-A368 PolarHBondContact ND2-O 2.74Å
355G97.7Very high97.3Very high22 Ų2247 Ų4723%0.22724%0.239CC..SBendtrans76.210.2-178.900000114.3R351 A352 A353R351-G355 VanDerWaalsContact NE-C 3.34Å; R351-G355 PolarHBondContact NE-O 2.7Å; R351-G355 PolarHBondContact NH2-O 3.33Å; A352-G355 WeakPolarHBondContact O-CA 3.1Å; A352-G355 PolarHBondContact O-N 2.73Å; A353-G355 PolarHBondContact O-N 2.69Å
356K98.6Very high97.5Very high62 Ų6245.4 Ų45.427%0.2722%0.222SC..  trans-106.2153.8-179.1-59.8-171.6171.9-116.60112R351 A352 N354 A368 T369 M370 D371R351-K356 WeakPolarHBondContact CA-O 3.42Å; A352-K356 PolarHBondContact N-O 3.49Å; N354-K356 VanDerWaalsContact C-N 3.27Å; N354-K356 PolarHBondContact O-N 3.34Å; N354-K356 WeakPolarHBondContact OD1-CB 3.42Å; N354-K356 PolarHBondContact OD1-N 3.46Å; K356-A368 HydrophobicContact CB-CB 4.35Å; K356-A368 WeakPolarHBondContact CB-O 3.41Å; K356-T369 PolarHBondContact NZ-O 2.83Å; K356-M370 CarbonylContact C-O 3.53Å; K356-M370 VanDerWaalsContact CA-O 3.29Å; K356-M370 WeakPolarHBondContact CA-O 3.24Å; K356-M370 WeakPolarHBondContact CB-O 3.35Å; K356-D371 WeakPolarHBondContact CE-OD1 3.29Å; K356-D371 IonicContact NZ-OD1 3.69Å; K356-D371 PolarHBondContact NZ-OD1 2.94Å; K356-D371 IonicContact NZ-OD2 2.74Å; K356-D371 PolarHBondContact NZ-OD2 2.9Å
357Y98.6Very high97.6Very high25 Ų2542.1 Ų42.110%0.09821%0.208CC..EExtended strand (participates in β ladder)trans-81.9140.5177.8-67.4-83.1000112E342 L350 R351 A368 T369 M370 A373E342-Y357 VanDerWaalsContact CD-OH 3.26Å; E342-Y357 PolarHBondContact OE1-OH 3.1Å; E342-Y357 WeakPolarHBondContact OE2-CE1 3.2Å; E342-Y357 PolarHBondContact OE2-OH 3.28Å; L350-Y357 WeakPolarHBondContact O-CA 3.27Å; R351-Y357 HydrophobicContact CB-CD1 4.18Å; R351-Y357 HydrophobicContact CB-CE1 4.14Å; Y357-A368 VanDerWaalsContact O-CA 3.31Å; Y357-A368 WeakPolarHBondContact O-CA 3.19Å; Y357-T369 PolarHBondContact O-N 2.87Å; Y357-M370 PolarHBondContact N-O 3.41Å; Y357-M370 PolarHBondContact O-N 3.23Å; Y357-A373 HydrophobicContact CD1-CB 3.54Å; Y357-A373 HydrophobicContact CD2-CB 3.91Å; Y357-A373 HydrophobicContact CE1-CB 3.74Å; Y357-A373 HydrophobicContact CE2-CB 4.1Å; Y357-A373 HydrophobicContact CG-CB 3.61Å
358V98.5Very high97.6Very high0 Ų039.1 Ų39.10%020%0.197CC..EExtended strand (participates in β ladder)trans-80.7135177.3-175.80000109.4L326 F339 L350 A352 L366 A367 A368 F379L326-V358 HydrophobicContact CD1-CB 4.37Å; L326-V358 HydrophobicContact CD1-CG1 3.52Å; L326-V358 HydrophobicContact CD1-CG2 3.84Å; L326-V358 HydrophobicContact CG-CG1 4.47Å; F339-V358 HydrophobicContact CD1-CG2 4.21Å; F339-V358 HydrophobicContact CE1-CG2 4.21Å; L350-V358 HydrophobicContact CB-CB 4.12Å; L350-V358 HydrophobicContact CB-CG2 3.94Å; L350-V358 WeakPolarHBondContact O-CG2 3.34Å; L350-V358 PolarHBondContact O-N 2.67Å; A352-V358 HydrophobicContact CB-CG2 4.42Å; V358-L366 HydrophobicContact CG1-CB 4.19Å; V358-L366 HydrophobicContact CG1-CD1 4.41Å; V358-A367 WeakPolarHBondContact CA-O 3.42Å; V358-A368 HydrophobicContact CG2-CB 4.13Å; V358-F379 HydrophobicContact CB-CE2 4.34Å; V358-F379 HydrophobicContact CB-CZ 4.43Å; V358-F379 HydrophobicContact CG1-CE2 4.36Å; V358-F379 HydrophobicContact CG1-CZ 3.96Å; V358-F379 WeakPolarHBondContact O-CE2 3.36Å
359A98Very high97.6Very high10 Ų1042.2 Ų42.28%0.08322%0.216CC..EExtended strand (participates in β ladder)trans-142159.2169.700000110.9L366 A367 E377A359-L366 WeakPolarHBondContact O-CA 3.44Å; A359-A367 PolarHBondContact N-O 2.96Å; A359-A367 PolarHBondContact O-N 2.9Å; A359-E377 HydrophobicContact CB-CG 4.03Å; A359-E377 WeakPolarHBondContact CB-OE1 3.34Å
360A97.4Very high97.4Very high22 Ų2245.9 Ų45.918%0.18223%0.234CC..EExtended strand (participates in β ladder)trans-79.4125.8167.100000110A270 A286 L366A270-A360 HydrophobicContact CB-CB 3.86Å; A286-A360 HydrophobicContact CB-CB 4.06Å; A360-L366 HydrophobicContact CB-CD2 3.89Å
361K96.3Very high97.3Very high90 Ų9051.7 Ų51.739%0.39127%0.265SS..  trans-68.1171.1169.9-68.6176.7-176.7169.20110.4N363 G364 Q365 A367K361-N363 VanDerWaalsContact CB-OD1 3.29Å; K361-N363 WeakPolarHBondContact CB-OD1 3.41Å; K361-N363 PolarHBondContact O-N 2.86Å; K361-G364 WeakPolarHBondContact O-CA 3.34Å; K361-G364 PolarHBondContact O-N 3.13Å; K361-Q365 WeakPolarHBondContact CB-O 3.21Å; K361-Q365 HydrophobicContact CD-CB 4.48Å; K361-Q365 WeakPolarHBondContact CG-O 3.36Å; K361-Q365 PolarHBondContact N-O 3.46Å; K361-A367 HydrophobicContact CD-CB 4.49Å; K361-A367 VanDerWaalsContact CE-CB 3.41Å
362K94.7Very high97.2Very high230 Ų23051 Ų51100%128%0.275SS*.THydrogen-bonded Turntrans-53.7-27.8175.4-66.5-173.5178.3-177.20114.3
363N94.3Very high97Very high93 Ų9351.7 Ų51.750%0.49728%0.281SS..THydrogen-bonded Turntrans-92.99.2176.868.1-12.4000113.5K361 Q365K361-N363 VanDerWaalsContact CB-OD1 3.29Å; K361-N363 WeakPolarHBondContact CB-OD1 3.41Å; K361-N363 PolarHBondContact O-N 2.86Å; N363-Q365 VanDerWaalsContact C-N 3.29Å; N363-Q365 PolarHBondContact ND2-OE1 2.89Å; N363-Q365 VanDerWaalsContact ND2-OE1 3.07Å; N363-Q365 PolarHBondContact O-N 2.89Å; N363-Q365 WeakPolarHBondContact OD1-CB 3.27Å; N363-Q365 PolarHBondContact OD1-N 2.94Å
364G96.7Very high96.8Very high3 Ų351.4 Ų51.43%0.03128%0.282CS..SBendtrans85.9-21.4-177.900000114.9S285 A286 K361 L366S285-G364 CarbonylContact C-O 3.5Å; S285-G364 WeakPolarHBondContact CA-O 3.11Å; S285-G364 PolarHBondContact OG-O 3.43Å; A286-G364 PolarHBondContact N-O 2.91Å; A286-G364 WeakPolarHBondContact O-CA 3.42Å; K361-G364 WeakPolarHBondContact O-CA 3.34Å; K361-G364 PolarHBondContact O-N 3.13Å; G364-L366 PolarHBondContact O-N 3.05Å
365Q98Very high96.6Very high49 Ų4956 Ų5623%0.22930%0.301CS..BIsolated β-bridgetrans-60.9134.9-175.5-71.5-177.2-34.900111.9D283 L284 S285 K361 N363D283-Q365 PolarHBondContact OD2-NE2 2.93Å; D283-Q365 VanDerWaalsContact OD2-NE2 3.16Å; L284-Q365 WeakPolarHBondContact O-CA 3.48Å; S285-Q365 PolarHBondContact OG-N 3.09Å; K361-Q365 WeakPolarHBondContact CB-O 3.21Å; K361-Q365 HydrophobicContact CD-CB 4.48Å; K361-Q365 WeakPolarHBondContact CG-O 3.36Å; K361-Q365 PolarHBondContact N-O 3.46Å; N363-Q365 VanDerWaalsContact C-N 3.29Å; N363-Q365 PolarHBondContact ND2-OE1 2.89Å; N363-Q365 VanDerWaalsContact ND2-OE1 3.07Å; N363-Q365 PolarHBondContact O-N 2.89Å; N363-Q365 WeakPolarHBondContact OD1-CB 3.27Å; N363-Q365 PolarHBondContact OD1-N 2.94Å
366L98.4Very high96.5Very high3 Ų358.6 Ų58.62%0.01632%0.316CS..EExtended strand (participates in β ladder)trans-81.1135.7178.6-59.7-167.5000111.7V276 L284 A286 W318 L326 V358 A359 A360 G364 F379V276-L366 HydrophobicContact CB-CD1 4.42Å; V276-L366 HydrophobicContact CG1-CD1 3.63Å; V276-L366 HydrophobicContact CG1-CG 4.41Å; V276-L366 HydrophobicContact CG2-CD1 3.83Å; V276-L366 HydrophobicContact CG2-CD2 4.37Å; L284-L366 HydrophobicContact CB-CB 4.37Å; L284-L366 HydrophobicContact CB-CD1 4.13Å; L284-L366 HydrophobicContact CB-CG 4.26Å; L284-L366 PolarHBondContact O-N 2.8Å; A286-L366 HydrophobicContact CB-CD2 4.33Å; W318-L366 HydrophobicContact CH2-CD1 3.91Å; W318-L366 HydrophobicContact CZ3-CD1 3.98Å; L326-L366 HydrophobicContact CB-CB 4.13Å; L326-L366 HydrophobicContact CD1-CB 4.13Å; L326-L366 HydrophobicContact CD1-CD1 4.45Å; L326-L366 HydrophobicContact CG-CB 4.33Å; L326-L366 PolarHBondContact N-O 2.89Å; V358-L366 HydrophobicContact CG1-CB 4.19Å; V358-L366 HydrophobicContact CG1-CD1 4.41Å; A359-L366 WeakPolarHBondContact O-CA 3.44Å; A360-L366 HydrophobicContact CB-CD2 3.89Å; G364-L366 PolarHBondContact O-N 3.05Å; L366-F379 HydrophobicContact CD2-CE1 4.29Å; L366-F379 HydrophobicContact CD2-CZ 4.37Å
367A98.3Very high96.5Very high1 Ų156.3 Ų56.31%0.00831%0.306CS..EExtended strand (participates in β ladder)trans-148.5145.817200000112.3G324 V358 A359 K361 T369G324-A367 CarbonylContact O-C 3.46Å; G324-A367 VanDerWaalsContact O-CA 3.26Å; G324-A367 WeakPolarHBondContact O-CA 3.19Å; G324-A367 WeakPolarHBondContact O-CB 3.31Å; V358-A367 WeakPolarHBondContact CA-O 3.42Å; A359-A367 PolarHBondContact N-O 2.96Å; A359-A367 PolarHBondContact O-N 2.9Å; K361-A367 HydrophobicContact CD-CB 4.49Å; K361-A367 VanDerWaalsContact CE-CB 3.41Å; A367-T369 HydrophobicContact CB-CG2 4.01Å; A367-T369 PolarHBondContact O-N 2.81Å
368A98.3Very high96.4Very high0 Ų057.4 Ų57.40%031%0.312CS..EExtended strand (participates in β ladder)trans-94.180.6174.400000110.6L320 G324 A352 N354 K356 Y357 V358L320-A368 HydrophobicContact CD1-CB 3.84Å; G324-A368 PolarHBondContact O-N 3.43Å; A352-A368 HydrophobicContact CB-CB 3.53Å; N354-A368 PolarHBondContact ND2-O 2.74Å; K356-A368 HydrophobicContact CB-CB 4.35Å; K356-A368 WeakPolarHBondContact CB-O 3.41Å; Y357-A368 VanDerWaalsContact O-CA 3.31Å; Y357-A368 WeakPolarHBondContact O-CA 3.19Å; V358-A368 HydrophobicContact CG2-CB 4.13Å
369T96.6Very high96.4Very high66 Ų6657.5 Ų57.541%0.40531%0.312SS..EExtended strand (participates in β ladder)trans-118.9-13-173.952.10000114.6K356 Y357 A367K356-T369 PolarHBondContact NZ-O 2.83Å; Y357-T369 PolarHBondContact O-N 2.87Å; A367-T369 HydrophobicContact CB-CG2 4.01Å; A367-T369 PolarHBondContact O-N 2.81Å
370M95.6Very high96.4Very high77 Ų7758.4 Ų58.438%0.37932%0.316SS..EExtended strand (participates in β ladder)trans-95.7132.1-171.4-61.1-57-68.500111.7K356 Y357 E377K356-M370 CarbonylContact C-O 3.53Å; K356-M370 VanDerWaalsContact CA-O 3.29Å; K356-M370 WeakPolarHBondContact CA-O 3.24Å; K356-M370 WeakPolarHBondContact CB-O 3.35Å; Y357-M370 PolarHBondContact N-O 3.41Å; Y357-M370 PolarHBondContact O-N 3.23Å; M370-E377 HydrophobicContact CB-CG 4.1Å; M370-E377 HydrophobicContact CG-CG 4.2Å; M370-E377 WeakPolarHBondContact CG-OE1 3.45Å
371D95.8Very high96.5Very high122 Ų12258 Ų5865%0.65231%0.31SS*.SBendtrans-82.5-19.1-179.5-60.7-46.8000112.4K356K356-D371 WeakPolarHBondContact CE-OD1 3.29Å; K356-D371 IonicContact NZ-OD1 3.69Å; K356-D371 PolarHBondContact NZ-OD1 2.94Å; K356-D371 IonicContact NZ-OD2 2.74Å; K356-D371 PolarHBondContact NZ-OD2 2.9Å
372S95.2Very high96.6Very high84 Ų8456.3 Ų56.359%0.58730%0.303SS*.SBendtrans-135.2139.6176.258.20000109.9
373A95Very high96.7Very high17 Ų1745.7 Ų45.714%0.1426%0.257CS..  trans-88.8121.7175.900000113.5R344 T349 Y357 E377R344-A373 PolarHBondContact NH1-O 3.22Å; T349-A373 HydrophobicContact CG2-CB 3.68Å; Y357-A373 HydrophobicContact CD1-CB 3.54Å; Y357-A373 HydrophobicContact CD2-CB 3.91Å; Y357-A373 HydrophobicContact CE1-CB 3.74Å; Y357-A373 HydrophobicContact CE2-CB 4.1Å; Y357-A373 HydrophobicContact CG-CB 3.61Å; A373-E377 HydrophobicContact CB-CB 3.78Å; A373-E377 HydrophobicContact CB-CG 4.25Å
374G93.9Very high96.8Very high34 Ų3442.4 Ų42.435%0.35124%0.239SC..  trans-109.6-161.4161.800000111.7S376 E377G374-S376 VanDerWaalsContact C-N 3.25Å; G374-S376 PolarHBondContact O-N 3.11Å; G374-E377 PolarHBondContact N-OE2 3.44Å; G374-E377 PolarHBondContact O-N 3.07Å; G374-E377 VanDerWaalsContact O-N 3.11Å
375E93.8Very high96.8Very high166 Ų16642.3 Ų42.378%0.77624%0.238SC*.G310 helixtrans-60.1-31-174.7-63.6178.5175.200113.6E377 E378E375-E377 VanDerWaalsContact C-N 3.28Å; E375-E377 PolarHBondContact O-N 3.31Å; E375-E378 PolarHBondContact O-N 2.98Å
376S94.9Very high96.7Very high77 Ų7740 Ų4054%0.53823%0.227SC..G310 helixtrans-72.8-18.9179.4-63.10000114G374G374-S376 VanDerWaalsContact C-N 3.25Å; G374-S376 PolarHBondContact O-N 3.11Å
377E97.7Very high96.5Very high13 Ų1341.7 Ų41.76%0.06124%0.238CC..G310 helixtrans-93.3-3.2177.3-6965.4-119.800112.1T349 A359 M370 A373 G374 E375 F379T349-E377 HydrophobicContact CG2-CB 4.42Å; A359-E377 HydrophobicContact CB-CG 4.03Å; A359-E377 WeakPolarHBondContact CB-OE1 3.34Å; M370-E377 HydrophobicContact CB-CG 4.1Å; M370-E377 HydrophobicContact CG-CG 4.2Å; M370-E377 WeakPolarHBondContact CG-OE1 3.45Å; A373-E377 HydrophobicContact CB-CB 3.78Å; A373-E377 HydrophobicContact CB-CG 4.25Å; G374-E377 PolarHBondContact N-OE2 3.44Å; G374-E377 PolarHBondContact O-N 3.07Å; G374-E377 VanDerWaalsContact O-N 3.11Å; E375-E377 VanDerWaalsContact C-N 3.28Å; E375-E377 PolarHBondContact O-N 3.31Å; E377-F379 VanDerWaalsContact O-CD2 3.24Å; E377-F379 WeakPolarHBondContact O-CD2 3.32Å; E377-F379 WeakPolarHBondContact O-CE2 3.24Å
378E97.8Very high96.4Very high49 Ų4941.7 Ų41.723%0.22924%0.238CC..EExtended strand (participates in β ladder)trans-80.8139.5179.3-67.3-170.3160.400111.7G271 R347 L348 T349 E375G271-E378 PolarHBondContact N-O 2.84Å; G271-E378 VanDerWaalsContact N-O 3.12Å; R347-E378 HydrophobicContact CB-CB 4.14Å; R347-E378 HydrophobicContact CB-CG 4.33Å; R347-E378 HydrophobicContact CG-CB 4.37Å; L348-E378 CarbonylContact O-C 3.5Å; L348-E378 WeakPolarHBondContact O-CA 3.44Å; T349-E378 HydrophobicContact CG2-CG 3.99Å; E375-E378 PolarHBondContact O-N 2.98Å
379F98.6Very high96.2Very high1 Ų141.7 Ų41.70%0.00424%0.238CC..EExtended strand (participates in β ladder)trans-122.1147.9174.6-64.7-99.1000110L268 T269 A270 V276 R347 L348 V358 L366 E377L268-F379 HydrophobicContact CB-CD1 4.41Å; L268-F379 HydrophobicContact CD2-CB 4.29Å; T269-F379 CarbonylContact O-C 3.47Å; T269-F379 WeakPolarHBondContact O-CA 3.41Å; A270-F379 HydrophobicContact CB-CD1 3.94Å; A270-F379 HydrophobicContact CB-CE1 3.59Å; A270-F379 HydrophobicContact CB-CZ 4.36Å; V276-F379 HydrophobicContact CG2-CE1 4.18Å; R347-F379 CarbonylContact C-O 3.59Å; R347-F379 WeakPolarHBondContact CA-O 3.4Å; L348-F379 HydrophobicContact CD1-CB 3.98Å; L348-F379 HydrophobicContact CG-CB 4.26Å; L348-F379 PolarHBondContact N-O 2.87Å; L348-F379 PolarHBondContact O-N 2.99Å; V358-F379 HydrophobicContact CB-CE2 4.34Å; V358-F379 HydrophobicContact CB-CZ 4.43Å; V358-F379 HydrophobicContact CG1-CE2 4.36Å; V358-F379 HydrophobicContact CG1-CZ 3.96Å; V358-F379 WeakPolarHBondContact O-CE2 3.36Å; L366-F379 HydrophobicContact CD2-CE1 4.29Å; L366-F379 HydrophobicContact CD2-CZ 4.37Å; E377-F379 VanDerWaalsContact O-CD2 3.24Å; E377-F379 WeakPolarHBondContact O-CD2 3.32Å; E377-F379 WeakPolarHBondContact O-CE2 3.24Å
380I98.3Very high96.2Very high30 Ų3038.5 Ų38.515%0.15422%0.219CC..EExtended strand (participates in β ladder)trans-95134161.5-63173.9000107.4L268 T269 R347 F421L268-I380 WeakPolarHBondContact CA-O 3.08Å; T269-I380 PolarHBondContact N-O 2.9Å; T269-I380 PolarHBondContact O-N 2.86Å; R347-I380 VanDerWaalsContact CD-CG1 3.43Å; R347-I380 VanDerWaalsContact CZ-CD1 3.48Å; R347-I380 VanDerWaalsContact CZ-CG1 3.5Å; I380-F421 HydrophobicContact CG2-CE1 4.36Å; I380-F421 HydrophobicContact CG2-CE2 4.36Å; I380-F421 HydrophobicContact CG2-CZ 3.5Å; I380-F421 VanDerWaalsContact CG2-CZ 3.5Å
381M98.1Very high96.3Very high13 Ų1334.9 Ų34.96%0.06420%0.201CC..EExtended strand (participates in β ladder)trans-118114.7175.8-172.1165.958.600110.9V266 L268 V299 W343 L348 Y426 F458V266-M381 HydrophobicContact CB-CG 3.68Å; V266-M381 HydrophobicContact CB-SD 4.17Å; V266-M381 HydrophobicContact CG1-CG 3.77Å; V266-M381 HydrophobicContact CG1-SD 3.98Å; V266-M381 HydrophobicContact CG2-CG 3.89Å; V266-M381 HydrophobicContact CG2-SD 3.88Å; L268-M381 HydrophobicContact CD2-CB 3.75Å; L268-M381 HydrophobicContact CD2-CG 3.78Å; L268-M381 HydrophobicContact CD2-SD 3.99Å; V299-M381 HydrophobicContact CG2-SD 4.42Å; W343-M381 HydrophobicContact CH2-CE 3.17Å; W343-M381 HydrophobicContact CZ2-CE 4.14Å; W343-M381 HydrophobicContact CZ3-CE 3.68Å; L348-M381 HydrophobicContact CD2-CB 3.58Å; L348-M381 HydrophobicContact CD2-CE 3.41Å; L348-M381 VanDerWaalsContact CD2-CE 3.41Å; L348-M381 HydrophobicContact CD2-CG 4.34Å; L348-M381 HydrophobicContact CD2-SD 3.9Å; M381-Y426 PolarHBondContact O-OH 2.72Å; M381-Y426 VanDerWaalsContact O-OH 3.08Å; M381-F458 HydrophobicContact CE-CD2 3.45Å; M381-F458 VanDerWaalsContact CE-CD2 3.45Å; M381-F458 HydrophobicContact CE-CE2 3.66Å; M381-F458 HydrophobicContact SD-CD2 4.43Å; M381-F458 HydrophobicContact SD-CE2 4.41Å
382K98.3Very high96.2Very high54 Ų5432 Ų3224%0.23518%0.18CC..EExtended strand (participates in β ladder)trans-104.2120.2179.4179.2-173.4-179.7-162.60109.9V266 V267 E291 I384 F421 Y426V266-K382 CarbonylContact C-O 3.51Å; V266-K382 WeakPolarHBondContact CA-O 3.47Å; V266-K382 WeakPolarHBondContact CB-O 3.39Å; V267-K382 PolarHBondContact N-O 3.01Å; V267-K382 PolarHBondContact O-N 2.89Å; E291-K382 IonicContact OE1-NZ 3Å; E291-K382 PolarHBondContact OE1-NZ 3.05Å; E291-K382 IonicContact OE2-NZ 3.04Å; E291-K382 PolarHBondContact OE2-NZ 2.88Å; K382-I384 HydrophobicContact CD-CG2 4.06Å; K382-I384 HydrophobicContact CG-CG2 4.05Å; K382-I384 PolarHBondContact O-N 2.92Å; K382-F421 HydrophobicContact CB-CD1 4.23Å; K382-F421 HydrophobicContact CB-CD2 4.26Å; K382-F421 HydrophobicContact CB-CE1 3.93Å; K382-F421 HydrophobicContact CB-CE2 3.94Å; K382-F421 HydrophobicContact CB-CG 4.36Å; K382-F421 HydrophobicContact CB-CZ 3.77Å; K382-F421 HydrophobicContact CD-CD1 3.81Å; K382-F421 HydrophobicContact CD-CE1 4.05Å; K382-F421 HydrophobicContact CD-CG 4.28Å; K382-F421 HydrophobicContact CG-CB 4.31Å; K382-F421 HydrophobicContact CG-CD1 3.72Å; K382-F421 HydrophobicContact CG-CD2 4.03Å; K382-F421 HydrophobicContact CG-CE1 3.94Å; K382-F421 HydrophobicContact CG-CE2 4.22Å; K382-F421 HydrophobicContact CG-CG 3.74Å; K382-F421 HydrophobicContact CG-CZ 4.17Å; K382-Y426 WeakPolarHBondContact CA-OH 3.37Å
383L97.8Very high96.1Very high8 Ų828.6 Ų28.64%0.04216%0.159CC..EExtended strand (participates in β ladder)trans-77.6112.4171.3178.662.1000108.9P264 V266 N385 R386 L419 Y426 F456 F458P264-L383 HydrophobicContact CB-CD1 3.83Å; V266-L383 HydrophobicContact CG1-CD1 4.4Å; L383-N385 WeakPolarHBondContact CD1-OD1 3.45Å; L383-R386 HydrophobicContact CD1-CG 4.26Å; L383-R386 HydrophobicContact CD2-CB 3.7Å; L383-R386 HydrophobicContact CD2-CG 3.69Å; L383-R386 HydrophobicContact CG-CB 3.93Å; L383-R386 HydrophobicContact CG-CG 4.02Å; L383-L419 HydrophobicContact CD2-CD2 4.21Å; L383-Y426 HydrophobicContact CB-CE1 4.15Å; L383-Y426 WeakPolarHBondContact CB-OH 3.49Å; L383-Y426 PolarHBondContact N-OH 3.37Å; L383-F456 HydrophobicContact CD2-CD2 4.32Å; L383-F456 HydrophobicContact CD2-CE2 4.48Å; L383-F458 HydrophobicContact CB-CZ 4.44Å; L383-F458 HydrophobicContact CD1-CZ 4.06Å; L383-F458 HydrophobicContact CD2-CZ 4.17Å; L383-F458 HydrophobicContact CG-CZ 4.46Å
384I96.2Very high95.7Very high23 Ų2333.3 Ų33.312%0.11818%0.178CC..  trans-98.1-29.6-171.361.7122000113.4V176 Q265 V267 V296 K382 R386V176-I384 WeakPolarHBondContact CG2-O 3.13Å; Q265-I384 HydrophobicContact CB-CG1 4.32Å; Q265-I384 VanDerWaalsContact O-CG1 3.27Å; Q265-I384 WeakPolarHBondContact O-CG1 3.47Å; Q265-I384 PolarHBondContact O-N 2.88Å; V267-I384 HydrophobicContact CB-CG2 4.33Å; V267-I384 HydrophobicContact CG2-CG2 3.74Å; V296-I384 HydrophobicContact CB-CD1 4.27Å; V296-I384 HydrophobicContact CG1-CD1 3.69Å; V296-I384 HydrophobicContact CG1-CG1 4.17Å; V296-I384 HydrophobicContact CG2-CD1 3.47Å; V296-I384 VanDerWaalsContact CG2-CD1 3.47Å; V296-I384 HydrophobicContact CG2-CG1 4.18Å; K382-I384 HydrophobicContact CD-CG2 4.06Å; K382-I384 HydrophobicContact CG-CG2 4.05Å; K382-I384 PolarHBondContact O-N 2.92Å; I384-R386 VanDerWaalsContact C-N 3.27Å; I384-R386 PolarHBondContact O-N 2.73Å
385N96.5Very high95.3Very high1 Ų136.8 Ų36.81%0.00519%0.185CC..SBendtrans-93.826.2-175.974.6-26.8000113.5S262 H263 Q265 L383S262-N385 PolarHBondContact OG-ND2 2.99Å; H263-N385 PolarHBondContact O-ND2 3.39Å; Q265-N385 HydrophobicContact CB-CB 4.14Å; Q265-N385 PolarHBondContact N-OD1 3.2Å; L383-N385 WeakPolarHBondContact CD1-OD1 3.45Å
386R96.4Very high95Very high2 Ų229.6 Ų29.61%0.00816%0.155CC..  trans-135.257.4170.5-66.3-62.5-172.9-78.6-2.6111.7S262 L383 I384 I388 I389 L419 Y498S262-R386 PolarHBondContact O-NH2 2.59Å; S262-R386 PolarHBondContact OG-NH1 3.43Å; L383-R386 HydrophobicContact CD1-CG 4.26Å; L383-R386 HydrophobicContact CD2-CB 3.7Å; L383-R386 HydrophobicContact CD2-CG 3.69Å; L383-R386 HydrophobicContact CG-CB 3.93Å; L383-R386 HydrophobicContact CG-CG 4.02Å; I384-R386 VanDerWaalsContact C-N 3.27Å; I384-R386 PolarHBondContact O-N 2.73Å; R386-I388 CarbonylContact C-O 3.6Å; R386-I388 WeakPolarHBondContact CA-O 3.38Å; R386-I388 PolarHBondContact O-N 3.34Å; R386-I389 HydrophobicContact CB-CB 4.4Å; R386-I389 HydrophobicContact CG-CD1 4.5Å; R386-I389 HydrophobicContact CG-CG1 4.49Å; R386-L419 HydrophobicContact CB-CD2 4.25Å; R386-L419 WeakPolarHBondContact O-CB 3.31Å; R386-L419 WeakPolarHBondContact O-CD2 3.11Å; R386-Y498 VanDerWaalsContact CZ-OXT 3.24Å; R386-Y498 PolarHBondContact NE-OXT 2.93Å; R386-Y498 PolarHBondContact NH2-O 2.88Å; R386-Y498 PolarHBondContact NH2-OXT 2.82Å
387P94.6Very high95Very high38 Ų3826.1 Ų26.125%0.24713%0.131CC..SBendtrans-61.7-27.9169.728.5-35.3000111.2V176 M179 S194 T418 L419V176-P387 HydrophobicContact CG2-CG 3.65Å; M179-P387 HydrophobicContact CE-CG 4.37Å; S194-P387 WeakPolarHBondContact O-CG 3.42Å; P387-T418 WeakPolarHBondContact O-CA 3.24Å; P387-L419 PolarHBondContact O-N 2.88Å
388I94.4Very high94.9Very high0 Ų025.6 Ų25.60%013%0.128CC..EExtended strand (participates in β ladder)trans-119.5145.4160.256.3175.4000109.4Q145 M179 N196 R386 Y416 F417Q145-I388 PolarHBondContact NE2-O 2.65Å; M179-I388 HydrophobicContact CE-CD1 4.23Å; M179-I388 HydrophobicContact CE-CG1 3.67Å; N196-I388 VanDerWaalsContact OD1-CG2 3.26Å; N196-I388 WeakPolarHBondContact OD1-CG2 3.4Å; R386-I388 CarbonylContact C-O 3.6Å; R386-I388 WeakPolarHBondContact CA-O 3.38Å; R386-I388 PolarHBondContact O-N 3.34Å; I388-Y416 HydrophobicContact CG2-CD2 4.38Å; I388-F417 CarbonylContact C-O 3.48Å; I388-F417 VanDerWaalsContact CA-O 3.24Å; I388-F417 WeakPolarHBondContact CA-O 3.33Å
389I95.9Very high94.8Very high0 Ų023.2 Ų23.20%012%0.117CC..EExtended strand (participates in β ladder)trans-131.3139-179.2-163.3165.7000110.8R386 L391 Y416 F417 L419 L428 F456R386-I389 HydrophobicContact CB-CB 4.4Å; R386-I389 HydrophobicContact CG-CD1 4.5Å; R386-I389 HydrophobicContact CG-CG1 4.49Å; I389-L391 HydrophobicContact CD1-CD2 3.82Å; I389-L391 HydrophobicContact CD1-CG 4.46Å; I389-L391 HydrophobicContact CG1-CD2 4.02Å; I389-L391 HydrophobicContact CG1-CG 4.31Å; I389-Y416 WeakPolarHBondContact O-CA 3.43Å; I389-F417 HydrophobicContact CG2-CB 4.22Å; I389-F417 PolarHBondContact N-O 3.37Å; I389-F417 PolarHBondContact O-N 2.79Å; I389-L419 HydrophobicContact CG2-CD1 4.42Å; I389-L428 HydrophobicContact CG2-CD2 4.13Å; I389-F456 HydrophobicContact CD1-CE2 3.75Å; I389-F456 HydrophobicContact CD1-CZ 4.22Å
390V96Very high94.6Very high0 Ų023.9 Ų23.90%012%0.122CC..  trans-108140.2164.9172.50000107H143 P144 Q145 T181 F397 Y414 Y498H143-V390 PolarHBondContact NE2-O 2.87Å; P144-V390 HydrophobicContact CG-CB 4.06Å; P144-V390 HydrophobicContact CG-CG1 3.82Å; P144-V390 HydrophobicContact CG-CG2 3.98Å; Q145-V390 HydrophobicContact CG-CB 4.4Å; Q145-V390 HydrophobicContact CG-CG2 4.37Å; T181-V390 HydrophobicContact CG2-CG2 4.44Å; V390-F397 HydrophobicContact CG1-CD1 3.67Å; V390-F397 HydrophobicContact CG1-CE1 3.89Å; V390-Y414 VanDerWaalsContact CG1-CB 3.45Å; V390-Y414 HydrophobicContact CG1-CD1 4.38Å; V390-Y414 HydrophobicContact CG1-CD2 4.19Å; V390-Y414 HydrophobicContact CG1-CG 3.75Å; V390-Y414 HydrophobicContact CG2-CD2 3.91Å; V390-Y414 HydrophobicContact CG2-CG 4.33Å; V390-Y498 WeakPolarHBondContact O-CA 3.25Å
391L96.6Very high94.3Very high0 Ų028 Ų280%014%0.135CC..  trans-122.5128.9179.9-67.6173.4000110.5I389 F397 I398 L428 W436 W496 E497I389-L391 HydrophobicContact CD1-CD2 3.82Å; I389-L391 HydrophobicContact CD1-CG 4.46Å; I389-L391 HydrophobicContact CG1-CD2 4.02Å; I389-L391 HydrophobicContact CG1-CG 4.31Å; L391-F397 CarbonylContact O-C 3.51Å; L391-F397 WeakPolarHBondContact O-CA 3.23Å; L391-I398 HydrophobicContact CB-CB 4.34Å; L391-I398 HydrophobicContact CB-CD1 3.71Å; L391-I398 HydrophobicContact CB-CG1 4.06Å; L391-I398 HydrophobicContact CD1-CD1 3.92Å; L391-I398 HydrophobicContact CG-CD1 4.49Å; L391-I398 PolarHBondContact O-N 2.76Å; L391-L428 HydrophobicContact CD1-CD2 4.16Å; L391-W436 HydrophobicContact CD1-CH2 3.87Å; L391-W436 HydrophobicContact CD1-CZ3 4.45Å; L391-W496 HydrophobicContact CB-CB 4.47Å; L391-W496 HydrophobicContact CD2-CB 3.96Å; L391-E497 CarbonylContact C-O 3.5Å; L391-E497 WeakPolarHBondContact CA-O 3.41Å
392R94.4Very high93.5Very high61 Ų6137.3 Ų37.323%0.2318%0.175CC..EExtended strand (participates in β ladder)trans-122.7117.5176.6-176.1170.772.6161.8-2.4111.6A141 F397 W496 E497A141-R392 PolarHBondContact O-NH1 3.36Å; R392-F397 HydrophobicContact CB-CD1 3.64Å; R392-F397 HydrophobicContact CB-CE1 3.74Å; R392-F397 HydrophobicContact CB-CG 4.43Å; R392-F397 HydrophobicContact CG-CD1 4.05Å; R392-F397 HydrophobicContact CG-CE1 4.07Å; R392-F397 HydrophobicContact CG-CG 4.46Å; R392-F397 HydrophobicContact CG-CZ 4.45Å; R392-W496 CarbonylContact O-C 3.58Å; R392-W496 WeakPolarHBondContact O-CA 3.26Å; R392-E497 HydrophobicContact CB-CB 4.28Å; R392-E497 IonicContact CZ-OE2 3.63Å; R392-E497 PolarHBondContact N-O 3.24Å; R392-E497 IonicContact NE-OE2 2.67Å; R392-E497 PolarHBondContact NE-OE2 3.07Å; R392-E497 IonicContact NH2-OE1 3.31Å; R392-E497 IonicContact NH2-OE2 2.69Å; R392-E497 PolarHBondContact NH2-OE2 3.21Å; R392-E497 PolarHBondContact O-N 3.24Å
393G92.2Very high92.9Very high13 Ų1341.6 Ų41.613%0.13421%0.206CC..EExtended strand (participates in β ladder)trans-94-170.2172.900000112.3H395 G396G393-H395 PolarHBondContact O-N 2.88Å; G393-G396 PolarHBondContact N-O 2.7Å; G393-G396 PolarHBondContact O-N 2.66Å
394E86.6Confident92.5Very high116 Ų11645.1 Ų45.154%0.54223%0.228SC..THydrogen-bonded Turntrans-58.3-34.7-179.8-174179169.700113.6
395H85.6Confident92.4Very high107 Ų10744.4 Ų44.450%0.49523%0.226SC..THydrogen-bonded Turntrans-103.9-1.9-171.2-58.8-36.3000114.3G393 N410G393-H395 PolarHBondContact O-N 2.88Å; H395-N410 HydrophobicContact CB-CB 4.16Å; H395-N410 WeakPolarHBondContact O-CA 3.25Å
396G89.1Confident92.3Very high15 Ų1545.7 Ų45.716%0.15523%0.234CC..EExtended strand (participates in β ladder)trans143.6-167.4-178.400000112.6G393 R411G393-G396 PolarHBondContact N-O 2.7Å; G393-G396 PolarHBondContact O-N 2.66Å; G396-R411 WeakPolarHBondContact CA-O 3.12Å
397F93.6Very high92.4Very high5 Ų545.6 Ų45.62%0.02223%0.234CC..EExtended strand (participates in β ladder)trans-80.7156.7177.2-64-82.9000111.9V390 L391 R392 S409 N410 R411 S412 Y414V390-F397 HydrophobicContact CG1-CD1 3.67Å; V390-F397 HydrophobicContact CG1-CE1 3.89Å; L391-F397 CarbonylContact O-C 3.51Å; L391-F397 WeakPolarHBondContact O-CA 3.23Å; R392-F397 HydrophobicContact CB-CD1 3.64Å; R392-F397 HydrophobicContact CB-CE1 3.74Å; R392-F397 HydrophobicContact CB-CG 4.43Å; R392-F397 HydrophobicContact CG-CD1 4.05Å; R392-F397 HydrophobicContact CG-CE1 4.07Å; R392-F397 HydrophobicContact CG-CG 4.46Å; R392-F397 HydrophobicContact CG-CZ 4.45Å; F397-S409 CarbonylContact O-C 3.51Å; F397-S409 WeakPolarHBondContact O-CA 3.33Å; F397-N410 PolarHBondContact O-N 2.68Å; F397-R411 PolarHBondContact N-O 2.91Å; F397-R411 WeakPolarHBondContact O-CB 3.44Å; F397-R411 PolarHBondContact O-N 3.21Å; F397-R411 VanDerWaalsContact O-N 3.1Å; F397-S412 WeakPolarHBondContact CD2-O 3.47Å; F397-Y414 AromaticContact CD1-CD1 3.89Å; F397-Y414 HydrophobicContact CD1-CD1 3.89Å; F397-Y414 HydrophobicContact CD1-CG 4.17Å; F397-Y414 HydrophobicContact CD2-CD1 4.01Å; F397-Y414 AromaticContact CE1-CD1 3.71Å; F397-Y414 HydrophobicContact CE1-CD1 3.71Å; F397-Y414 HydrophobicContact CE1-CG 4.32Å; F397-Y414 AromaticContact CE2-CD1 3.85Å; F397-Y414 HydrophobicContact CE2-CD1 3.85Å; F397-Y414 HydrophobicContact CG-CD1 4.02Å; F397-Y414 HydrophobicContact CG-CG 4.36Å; F397-Y414 AromaticContact CZ-CD1 3.69Å; F397-Y414 HydrophobicContact CZ-CD1 3.69Å; F397-Y414 HydrophobicContact CZ-CE1 4.27Å
398I96.3Very high92.4Very high1 Ų144 Ų441%0.00522%0.223CC..EExtended strand (participates in β ladder)trans-76.9132.1164.2-58.7-178.2000109.1L391 L407 D408 D415 F417 W436 L483 W496L391-I398 HydrophobicContact CB-CB 4.34Å; L391-I398 HydrophobicContact CB-CD1 3.71Å; L391-I398 HydrophobicContact CB-CG1 4.06Å; L391-I398 HydrophobicContact CD1-CD1 3.92Å; L391-I398 HydrophobicContact CG-CD1 4.49Å; L391-I398 PolarHBondContact O-N 2.76Å; I398-L407 HydrophobicContact CG2-CB 4.28Å; I398-L407 HydrophobicContact CG2-CD2 4.34Å; I398-D408 CarbonylContact C-O 3.5Å; I398-D408 VanDerWaalsContact CA-O 3.23Å; I398-D408 WeakPolarHBondContact CA-O 3.31Å; I398-D415 PolarHBondContact O-N 2.92Å; I398-F417 HydrophobicContact CB-CE2 4.41Å; I398-F417 HydrophobicContact CG2-CE2 4.03Å; I398-F417 HydrophobicContact CG2-CZ 4.06Å; I398-W436 HydrophobicContact CD1-CH2 3.76Å; I398-W436 HydrophobicContact CG2-CH2 3.89Å; I398-W436 HydrophobicContact CG2-CZ2 3.84Å; I398-L483 HydrophobicContact CD1-CD1 4.17Å; I398-L483 HydrophobicContact CD1-CD2 3.9Å; I398-L483 HydrophobicContact CG2-CD2 4.3Å; I398-W496 HydrophobicContact CD1-CD2 4.1Å; I398-W496 HydrophobicContact CD1-CE3 3.61Å; I398-W496 HydrophobicContact CD1-CH2 3.96Å; I398-W496 HydrophobicContact CD1-CZ2 4.39Å; I398-W496 HydrophobicContact CD1-CZ3 3.55Å; I398-W496 HydrophobicContact CG1-CE3 3.89Å; I398-W496 HydrophobicContact CG1-CH2 4.18Å; I398-W496 HydrophobicContact CG1-CZ3 3.52Å
399G94.8Very high92.5Very high0 Ų044.2 Ų44.20%022%0.224CC..EExtended strand (participates in β ladder)trans-147.7152.6173.700000112.1L407 D408 D415G399-L407 WeakPolarHBondContact O-CA 3.42Å; G399-D408 PolarHBondContact N-O 2.89Å; G399-D408 PolarHBondContact O-N 2.88Å; G399-D415 VanDerWaalsContact CA-OD2 3.31Å; G399-D415 WeakPolarHBondContact CA-OD2 3.3Å
400C94.6Very high92.2Very high15 Ų1546.7 Ų46.710%0.10124%0.238CC..EExtended strand (participates in β ladder)trans-98.4133.9-175.2-174.30000111.7K402 L407 D415C400-K402 PolarHBondContact O-N 3.09Å; C400-L407 HydrophobicContact CB-CD2 3.79Å; C400-D415 PolarHBondContact N-OD2 2.67Å
401R91.9Very high91.9Very high116 Ų11651.7 Ų51.744%0.43826%0.257SS..  trans-78.9108.5166.9-63.1-171.5-169.1177.97.3109.1V403 T404 G405 T406 D408R401-V403 PolarHBondContact O-N 3.38Å; R401-T404 WeakPolarHBondContact CB-OG1 3.37Å; R401-T404 PolarHBondContact O-N 3.32Å; R401-T404 VanDerWaalsContact O-N 3.12Å; R401-G405 PolarHBondContact O-N 2.73Å; R401-T406 PolarHBondContact N-O 3.15Å; R401-D408 WeakPolarHBondContact CG-OD2 3.49Å; R401-D408 IonicContact CZ-OD1 3.69Å; R401-D408 IonicContact CZ-OD2 3.11Å; R401-D408 IonicContact NE-OD1 2.87Å; R401-D408 PolarHBondContact NE-OD1 2.85Å; R401-D408 IonicContact NE-OD2 3.19Å; R401-D408 PolarHBondContact NE-OD2 3.43Å; R401-D408 IonicContact NH2-OD1 3.27Å; R401-D408 PolarHBondContact NH2-OD1 2.88Å; R401-D408 IonicContact NH2-OD2 2.72Å; R401-D408 PolarHBondContact NH2-OD2 2.96Å
402K80.9Confident91.1Very high208 Ų20852.7 Ų52.790%0.90426%0.263SS*.THydrogen-bonded Turntrans-47.7-31.3-174.7-65-172176.9-174.40116.3C400C400-K402 PolarHBondContact O-N 3.09Å
403V86.1Confident90.7Very high145 Ų14552.3 Ų52.388%0.87927%0.27SS*.THydrogen-bonded Turntrans-86.9-40.8-176.6-178.90000112.1R401R401-V403 PolarHBondContact O-N 3.38Å
404T89.4Confident90.6Very high81 Ų8152.5 Ų52.550%0.49727%0.267SS..THydrogen-bonded Turntrans-103.3-12.5-170.961.10000113.4R401 T406R401-T404 WeakPolarHBondContact CB-OG1 3.37Å; R401-T404 PolarHBondContact O-N 3.32Å; R401-T404 VanDerWaalsContact O-N 3.12Å; T404-T406 WeakPolarHBondContact CB-OG1 3.22Å; T404-T406 PolarHBondContact O-N 3.2Å; T404-T406 WeakPolarHBondContact OG1-CB 3.43Å; T404-T406 PolarHBondContact OG1-N 2.93Å; T404-T406 PolarHBondContact OG1-OG1 3.12Å
405G93.8Very high90.8Very high8 Ų850 Ų508%0.08226%0.257CS..  trans69.91.7-170.100000113.4R401 L407 V445 S446R401-G405 PolarHBondContact O-N 2.73Å; G405-L407 PolarHBondContact O-N 3.4Å; G405-V445 CarbonylContact O-C 3.57Å; G405-V445 WeakPolarHBondContact O-CA 3.35Å; G405-S446 WeakPolarHBondContact CA-O 3.4Å; G405-S446 PolarHBondContact O-N 3.12Å
406T95.9Very high91.2Very high28 Ų2846.8 Ų46.817%0.17224%0.241CC..BIsolated β-bridgetrans-63.5130.8-178.1-51.60000110.4R401 T404 V482R401-T406 PolarHBondContact N-O 3.15Å; T404-T406 WeakPolarHBondContact CB-OG1 3.22Å; T404-T406 PolarHBondContact O-N 3.2Å; T404-T406 WeakPolarHBondContact OG1-CB 3.43Å; T404-T406 PolarHBondContact OG1-N 2.93Å; T404-T406 PolarHBondContact OG1-OG1 3.12Å; T406-V482 HydrophobicContact CG2-CG1 4.11Å
407L97.4Very high91.5Very high0 Ų046.1 Ų46.10%023%0.234CC..EExtended strand (participates in β ladder)trans-93.5122.4175.6-61.1173.6000109.9I398 G399 C400 G405 F417 W436 V444 L483I398-L407 HydrophobicContact CG2-CB 4.28Å; I398-L407 HydrophobicContact CG2-CD2 4.34Å; G399-L407 WeakPolarHBondContact O-CA 3.42Å; C400-L407 HydrophobicContact CB-CD2 3.79Å; G405-L407 PolarHBondContact O-N 3.4Å; L407-F417 HydrophobicContact CD2-CE1 4.09Å; L407-F417 HydrophobicContact CD2-CZ 4.08Å; L407-W436 HydrophobicContact CD1-CD2 3.45Å; L407-W436 VanDerWaalsContact CD1-CD2 3.45Å; L407-W436 HydrophobicContact CD1-CE3 3.92Å; L407-W436 HydrophobicContact CD1-CG 3.85Å; L407-W436 HydrophobicContact CD1-CH2 4.13Å; L407-W436 HydrophobicContact CD1-CZ2 3.69Å; L407-W436 HydrophobicContact CD1-CZ3 4.24Å; L407-W436 HydrophobicContact CD2-CZ2 4.4Å; L407-V444 HydrophobicContact CD1-CB 4.26Å; L407-V444 HydrophobicContact CD1-CG1 3.76Å; L407-V444 PolarHBondContact N-O 3.31Å; L407-L483 HydrophobicContact CB-CB 3.94Å; L407-L483 HydrophobicContact CB-CD2 3.99Å; L407-L483 HydrophobicContact CD1-CD2 3.89Å; L407-L483 WeakPolarHBondContact O-CB 3.43Å; L407-L483 PolarHBondContact O-N 3.02Å
408D95.9Very high91.6Very high6 Ų647.9 Ų47.93%0.03225%0.245CC..EExtended strand (participates in β ladder)trans-103138.3171.7-63.9-53.9000109.2I398 G399 R401 R411 G481I398-D408 CarbonylContact C-O 3.5Å; I398-D408 VanDerWaalsContact CA-O 3.23Å; I398-D408 WeakPolarHBondContact CA-O 3.31Å; G399-D408 PolarHBondContact N-O 2.89Å; G399-D408 PolarHBondContact O-N 2.88Å; R401-D408 WeakPolarHBondContact CG-OD2 3.49Å; R401-D408 IonicContact CZ-OD1 3.69Å; R401-D408 IonicContact CZ-OD2 3.11Å; R401-D408 IonicContact NE-OD1 2.87Å; R401-D408 PolarHBondContact NE-OD1 2.85Å; R401-D408 IonicContact NE-OD2 3.19Å; R401-D408 PolarHBondContact NE-OD2 3.43Å; R401-D408 IonicContact NH2-OD1 3.27Å; R401-D408 PolarHBondContact NH2-OD1 2.88Å; R401-D408 IonicContact NH2-OD2 2.72Å; R401-D408 PolarHBondContact NH2-OD2 2.96Å; D408-R411 HydrophobicContact CB-CG 3.85Å; D408-G481 CarbonylContact C-O 3.54Å; D408-G481 VanDerWaalsContact CA-O 3.23Å; D408-G481 WeakPolarHBondContact CA-O 3.36Å
409S94.6Very high91.6Very high3 Ų348.8 Ų48.82%0.02125%0.25CC..EExtended strand (participates in β ladder)trans-108.422-18068.90000113.9F397 G477 G481 W496F397-S409 CarbonylContact O-C 3.51Å; F397-S409 WeakPolarHBondContact O-CA 3.33Å; S409-G477 WeakPolarHBondContact OG-CA 3.31Å; S409-G481 PolarHBondContact N-O 2.99Å; S409-G481 PolarHBondContact OG-O 3.17Å; S409-W496 VanDerWaalsContact CB-CH2 3.49Å
410N90.9Very high91.7Very high53 Ų5351.6 Ų51.628%0.28326%0.263SS..EExtended strand (participates in β ladder)trans-126.722.1-178.666.42.8000112.4H395 F397 A480H395-N410 HydrophobicContact CB-CB 4.16Å; H395-N410 WeakPolarHBondContact O-CA 3.25Å; F397-N410 PolarHBondContact O-N 2.68Å; N410-A480 PolarHBondContact ND2-O 2.92Å; N410-A480 VanDerWaalsContact ND2-O 3.14Å
411R88.9Confident91.9Very high105 Ų10554 Ų5440%0.39627%0.272SS..EExtended strand (participates in β ladder)trans-81.9142.2-173-56-80.2-84.9168.9-5.9109.7G396 F397 D408 S413G396-R411 WeakPolarHBondContact CA-O 3.12Å; F397-R411 PolarHBondContact N-O 2.91Å; F397-R411 WeakPolarHBondContact O-CB 3.44Å; F397-R411 PolarHBondContact O-N 3.21Å; F397-R411 VanDerWaalsContact O-N 3.1Å; D408-R411 HydrophobicContact CB-CG 3.85Å; R411-S413 WeakPolarHBondContact CB-O 3.32Å
412S81.2Confident92.1Very high20 Ų2054.1 Ų54.114%0.1427%0.272CS..SBendtrans-76.7-33.5172.251.60000112.1M44 H139 F397M44-S412 VanDerWaalsContact N-CB 3.32Å; H139-S412 PolarHBondContact CE1-O 2.81Å; F397-S412 WeakPolarHBondContact CD2-O 3.47Å
413S85.1Confident92.8Very high53 Ų5347.9 Ų47.937%0.37125%0.249SC..SBendtrans-102.2138.8174.1-57.90000109.4R411R411-S413 WeakPolarHBondContact CB-O 3.32Å
414Y89.1Confident93.3Very high18 Ų1841.5 Ų41.57%0.07121%0.212CC..PPolyproline II helixtrans-86.1147.3176.340.6-86.9000111.2P144 L182 F184 V390 F397P144-Y414 HydrophobicContact CB-CE1 3.9Å; P144-Y414 HydrophobicContact CB-CE2 4Å; P144-Y414 HydrophobicContact CG-CD1 3.94Å; P144-Y414 HydrophobicContact CG-CD2 4.06Å; P144-Y414 HydrophobicContact CG-CE1 3.74Å; P144-Y414 HydrophobicContact CG-CE2 3.87Å; P144-Y414 HydrophobicContact CG-CG 4.12Å; L182-Y414 PolarHBondContact O-OH 2.9Å; F184-Y414 PolarHBondContact N-OH 2.92Å; F184-Y414 VanDerWaalsContact N-OH 3.14Å; V390-Y414 VanDerWaalsContact CG1-CB 3.45Å; V390-Y414 HydrophobicContact CG1-CD1 4.38Å; V390-Y414 HydrophobicContact CG1-CD2 4.19Å; V390-Y414 HydrophobicContact CG1-CG 3.75Å; V390-Y414 HydrophobicContact CG2-CD2 3.91Å; V390-Y414 HydrophobicContact CG2-CG 4.33Å; F397-Y414 AromaticContact CD1-CD1 3.89Å; F397-Y414 HydrophobicContact CD1-CD1 3.89Å; F397-Y414 HydrophobicContact CD1-CG 4.17Å; F397-Y414 HydrophobicContact CD2-CD1 4.01Å; F397-Y414 AromaticContact CE1-CD1 3.71Å; F397-Y414 HydrophobicContact CE1-CD1 3.71Å; F397-Y414 HydrophobicContact CE1-CG 4.32Å; F397-Y414 AromaticContact CE2-CD1 3.85Å; F397-Y414 HydrophobicContact CE2-CD1 3.85Å; F397-Y414 HydrophobicContact CG-CD1 4.02Å; F397-Y414 HydrophobicContact CG-CG 4.36Å; F397-Y414 AromaticContact CZ-CD1 3.69Å; F397-Y414 HydrophobicContact CZ-CD1 3.69Å; F397-Y414 HydrophobicContact CZ-CE1 4.27Å
415D92.4Very high93.7Very high63 Ų6337.6 Ų37.634%0.33719%0.189SC..PPolyproline II helixtrans-94.1159.1148.7-66.3-44.7000108.5I398 G399 C400 F417I398-D415 PolarHBondContact O-N 2.92Å; G399-D415 VanDerWaalsContact CA-OD2 3.31Å; G399-D415 WeakPolarHBondContact CA-OD2 3.3Å; C400-D415 PolarHBondContact N-OD2 2.67Å; D415-F417 HydrophobicContact CB-CE2 4.35Å; D415-F417 HydrophobicContact CB-CZ 3.99Å
416Y92.3Very high93.9Very high39 Ų3937.5 Ų37.515%0.15319%0.186CC..  trans-111.4150.2170.655.2-94.4000109.3V183 R185 I388 I389V183-Y416 HydrophobicContact CG1-CE1 4.41Å; V183-Y416 HydrophobicContact CG2-CD1 4.42Å; V183-Y416 HydrophobicContact CG2-CE1 4.26Å; R185-Y416 PolarHBondContact NH2-OH 3.45Å; I388-Y416 HydrophobicContact CG2-CD2 4.38Å; I389-Y416 WeakPolarHBondContact O-CA 3.43Å
417F95.4Very high94Very high1 Ų136.2 Ų36.20%0.00418%0.178CC..EExtended strand (participates in β ladder)trans-124.3136.5-175.9-55.3-82000109.5I388 I389 I398 L407 D415 L428 Q429 D430 W436I388-F417 CarbonylContact C-O 3.48Å; I388-F417 VanDerWaalsContact CA-O 3.24Å; I388-F417 WeakPolarHBondContact CA-O 3.33Å; I389-F417 HydrophobicContact CG2-CB 4.22Å; I389-F417 PolarHBondContact N-O 3.37Å; I389-F417 PolarHBondContact O-N 2.79Å; I398-F417 HydrophobicContact CB-CE2 4.41Å; I398-F417 HydrophobicContact CG2-CE2 4.03Å; I398-F417 HydrophobicContact CG2-CZ 4.06Å; L407-F417 HydrophobicContact CD2-CE1 4.09Å; L407-F417 HydrophobicContact CD2-CZ 4.08Å; D415-F417 HydrophobicContact CB-CE2 4.35Å; D415-F417 HydrophobicContact CB-CZ 3.99Å; F417-L428 HydrophobicContact CB-CB 4.33Å; F417-L428 HydrophobicContact CB-CD2 4.39Å; F417-Q429 CarbonylContact C-O 3.48Å; F417-Q429 VanDerWaalsContact CA-O 3.29Å; F417-Q429 WeakPolarHBondContact CA-O 3.41Å; F417-D430 HydrophobicContact CD1-CB 4.15Å; F417-D430 HydrophobicContact CE1-CB 4.23Å; F417-W436 AromaticContact CD1-CE2 3.89Å; F417-W436 HydrophobicContact CD1-CZ2 4.04Å; F417-W436 AromaticContact CD1-NE1 3.19Å; F417-W436 AromaticContact CD2-CZ2 3.77Å; F417-W436 HydrophobicContact CD2-CZ2 3.77Å; F417-W436 AromaticContact CE1-CE2 3.9Å; F417-W436 AromaticContact CE1-CZ2 3.9Å; F417-W436 HydrophobicContact CE1-CZ2 3.9Å; F417-W436 AromaticContact CE1-NE1 3.26Å; F417-W436 VanDerWaalsContact CE1-NE1 3.26Å; F417-W436 AromaticContact CE2-CZ2 3.64Å; F417-W436 HydrophobicContact CE2-CZ2 3.64Å; F417-W436 AromaticContact CG-CZ2 3.98Å; F417-W436 HydrophobicContact CG-CZ2 3.98Å; F417-W436 AromaticContact CG-NE1 3.85Å; F417-W436 AromaticContact CZ-CZ2 3.7Å; F417-W436 HydrophobicContact CZ-CZ2 3.7Å; F417-W436 AromaticContact CZ-NE1 3.98Å
418T96Very high94.1Very high43 Ų4336.2 Ų36.226%0.26418%0.178SC..EExtended strand (participates in β ladder)trans-70.6130.6170.1-660000108.6P387 L428 Q429P387-T418 WeakPolarHBondContact O-CA 3.24Å; T418-L428 WeakPolarHBondContact O-CA 3.32Å; T418-Q429 PolarHBondContact N-O 3.37Å; T418-Q429 PolarHBondContact O-N 2.88Å
419L97Very high94.1Very high19 Ų1937.8 Ų37.810%0.09919%0.185CC..EExtended strand (participates in β ladder)trans-105.1117.4-177.9-165.669000109.4L383 R386 P387 I389 Y426 L428 F456L383-L419 HydrophobicContact CD2-CD2 4.21Å; R386-L419 HydrophobicContact CB-CD2 4.25Å; R386-L419 WeakPolarHBondContact O-CB 3.31Å; R386-L419 WeakPolarHBondContact O-CD2 3.11Å; P387-L419 PolarHBondContact O-N 2.88Å; I389-L419 HydrophobicContact CG2-CD1 4.42Å; L419-Y426 HydrophobicContact CD1-CD1 3.94Å; L419-Y426 HydrophobicContact CD1-CG 4.1Å; L419-Y426 HydrophobicContact CD2-CD1 3.61Å; L419-Y426 HydrophobicContact CD2-CE1 3.88Å; L419-Y426 HydrophobicContact CD2-CG 4.38Å; L419-Y426 HydrophobicContact CG-CD1 3.61Å; L419-Y426 HydrophobicContact CG-CE1 4.34Å; L419-Y426 HydrophobicContact CG-CG 4.28Å; L419-L428 HydrophobicContact CD1-CD1 4.34Å; L419-L428 HydrophobicContact CD1-CD2 4.39Å; L419-L428 HydrophobicContact CD1-CG 3.85Å; L419-F456 HydrophobicContact CD1-CE2 3.9Å; L419-F456 HydrophobicContact CD1-CZ 3.71Å; L419-F456 HydrophobicContact CD2-CE2 3.86Å
420E97.3Very high94.2Very high60 Ų6038.3 Ų38.328%0.2819%0.187SC..EExtended strand (participates in β ladder)trans-105.3123.4175.5-71.2-178.4-161.500110Y426 S427 Y435E420-Y426 CarbonylContact O-C 3.35Å; E420-Y426 VanDerWaalsContact O-CA 3.25Å; E420-Y426 WeakPolarHBondContact O-CA 3.45Å; E420-S427 PolarHBondContact N-O 2.93Å; E420-S427 PolarHBondContact O-N 3.49Å; E420-Y435 VanDerWaalsContact CD-OH 3.23Å; E420-Y435 PolarHBondContact OE1-OH 2.66Å; E420-Y435 PolarHBondContact OE2-OH 3.37Å; E420-Y435 VanDerWaalsContact OE2-OH 3.12Å
421F97.9Very high94.1Very high66 Ų6640.9 Ų40.929%0.28921%0.21SC..EExtended strand (participates in β ladder)trans-91.4132.8177.4176.7-102.2000111.4I380 K382 A425 Y426I380-F421 HydrophobicContact CG2-CE1 4.36Å; I380-F421 HydrophobicContact CG2-CE2 4.36Å; I380-F421 HydrophobicContact CG2-CZ 3.5Å; I380-F421 VanDerWaalsContact CG2-CZ 3.5Å; K382-F421 HydrophobicContact CB-CD1 4.23Å; K382-F421 HydrophobicContact CB-CD2 4.26Å; K382-F421 HydrophobicContact CB-CE1 3.93Å; K382-F421 HydrophobicContact CB-CE2 3.94Å; K382-F421 HydrophobicContact CB-CG 4.36Å; K382-F421 HydrophobicContact CB-CZ 3.77Å; K382-F421 HydrophobicContact CD-CD1 3.81Å; K382-F421 HydrophobicContact CD-CE1 4.05Å; K382-F421 HydrophobicContact CD-CG 4.28Å; K382-F421 HydrophobicContact CG-CB 4.31Å; K382-F421 HydrophobicContact CG-CD1 3.72Å; K382-F421 HydrophobicContact CG-CD2 4.03Å; K382-F421 HydrophobicContact CG-CE1 3.94Å; K382-F421 HydrophobicContact CG-CE2 4.22Å; K382-F421 HydrophobicContact CG-CG 3.74Å; K382-F421 HydrophobicContact CG-CZ 4.17Å; F421-A425 WeakPolarHBondContact CD2-O 3.36Å; F421-Y426 HydrophobicContact CB-CD1 4.21Å; F421-Y426 HydrophobicContact CB-CE1 4.08Å; F421-Y426 HydrophobicContact CD2-CD1 4.01Å; F421-Y426 AromaticContact CD2-CE1 3.5Å; F421-Y426 HydrophobicContact CD2-CE1 3.5Å; F421-Y426 HydrophobicContact CD2-CE2 4.29Å; F421-Y426 AromaticContact CD2-CZ 3.63Å; F421-Y426 HydrophobicContact CE2-CE1 4.4Å; F421-Y426 HydrophobicContact CG-CE1 4.25Å
422R96.6Very high94.3Very high117 Ų11741 Ų4144%0.44222%0.222SC..EExtended strand (participates in β ladder)trans-144.5111.4173.3-174.9-176.3-62.2146.95.1110.8G424 A425R422-G424 VanDerWaalsContact C-N 3.31Å; R422-G424 PolarHBondContact O-N 2.71Å; R422-A425 PolarHBondContact N-O 2.79Å; R422-A425 PolarHBondContact O-N 3.11Å
423D95.3Very high94.9Very high77 Ų7741.4 Ų41.441%0.41223%0.23SC..THydrogen-bonded Turntrans49.947.3169.7-176.934.7000113.4K346 R347 A425K346-D423 WeakPolarHBondContact CB-O 3.17Å; K346-D423 WeakPolarHBondContact CD-O 3.21Å; R347-D423 IonicContact CZ-OD1 2.66Å; R347-D423 PolarHBondContact NH1-O 3.22Å; R347-D423 VanDerWaalsContact NH1-O 3.15Å; R347-D423 IonicContact NH1-OD1 2.67Å; R347-D423 PolarHBondContact NH1-OD1 3.27Å; R347-D423 IonicContact NH1-OD2 3.8Å; R347-D423 IonicContact NH2-OD1 3.23Å; R347-D423 PolarHBondContact NH2-OD1 3.09Å; R347-D423 IonicContact NH2-OD2 2.7Å; D423-A425 VanDerWaalsContact C-N 3.29Å; D423-A425 PolarHBondContact O-N 2.8Å
424G96.5Very high95.4Very high11 Ų1141.8 Ų41.811%0.11323%0.225CC..THydrogen-bonded Turntrans82.2-0.4178.700000115.6K346 R422K346-G424 WeakPolarHBondContact O-CA 3.46Å; R422-G424 VanDerWaalsContact C-N 3.31Å; R422-G424 PolarHBondContact O-N 2.71Å
425A98.3Very high95.9Very high0 Ų042 Ų420%023%0.226CC..EExtended strand (participates in β ladder)trans-113.4167.2169.100000111.4K346 F421 R422 D423 D453 L455K346-A425 HydrophobicContact CG-CB 4.4Å; F421-A425 WeakPolarHBondContact CD2-O 3.36Å; R422-A425 PolarHBondContact N-O 2.79Å; R422-A425 PolarHBondContact O-N 3.11Å; D423-A425 VanDerWaalsContact C-N 3.29Å; D423-A425 PolarHBondContact O-N 2.8Å; A425-D453 HydrophobicContact CB-CB 3.79Å; A425-L455 HydrophobicContact CB-CD2 3.98Å
426Y98.6Very high96.1Very high6 Ų639 Ų392%0.02421%0.209CC..EExtended strand (participates in β ladder)trans-127.2143.2178.4-60-88.3000111.3M381 K382 L383 L419 E420 F421 F454 F456M381-Y426 PolarHBondContact O-OH 2.72Å; M381-Y426 VanDerWaalsContact O-OH 3.08Å; K382-Y426 WeakPolarHBondContact CA-OH 3.37Å; L383-Y426 HydrophobicContact CB-CE1 4.15Å; L383-Y426 WeakPolarHBondContact CB-OH 3.49Å; L383-Y426 PolarHBondContact N-OH 3.37Å; L419-Y426 HydrophobicContact CD1-CD1 3.94Å; L419-Y426 HydrophobicContact CD1-CG 4.1Å; L419-Y426 HydrophobicContact CD2-CD1 3.61Å; L419-Y426 HydrophobicContact CD2-CE1 3.88Å; L419-Y426 HydrophobicContact CD2-CG 4.38Å; L419-Y426 HydrophobicContact CG-CD1 3.61Å; L419-Y426 HydrophobicContact CG-CE1 4.34Å; L419-Y426 HydrophobicContact CG-CG 4.28Å; E420-Y426 CarbonylContact O-C 3.35Å; E420-Y426 VanDerWaalsContact O-CA 3.25Å; E420-Y426 WeakPolarHBondContact O-CA 3.45Å; F421-Y426 HydrophobicContact CB-CD1 4.21Å; F421-Y426 HydrophobicContact CB-CE1 4.08Å; F421-Y426 HydrophobicContact CD2-CD1 4.01Å; F421-Y426 AromaticContact CD2-CE1 3.5Å; F421-Y426 HydrophobicContact CD2-CE1 3.5Å; F421-Y426 HydrophobicContact CD2-CE2 4.29Å; F421-Y426 AromaticContact CD2-CZ 3.63Å; F421-Y426 HydrophobicContact CE2-CE1 4.4Å; F421-Y426 HydrophobicContact CG-CE1 4.25Å; Y426-F454 PolarHBondContact N-O 2.91Å; Y426-F454 PolarHBondContact O-N 2.88Å; Y426-F456 HydrophobicContact CD2-CB 4.04Å; Y426-F456 HydrophobicContact CD2-CD1 4.1Å; Y426-F456 AromaticContact CD2-CD2 3.94Å; Y426-F456 HydrophobicContact CD2-CD2 3.94Å; Y426-F456 HydrophobicContact CD2-CE2 4.46Å; Y426-F456 AromaticContact CD2-CG 3.75Å; Y426-F456 HydrophobicContact CD2-CG 3.75Å; Y426-F456 HydrophobicContact CE2-CB 3.92Å; Y426-F456 HydrophobicContact CE2-CD2 4.08Å; Y426-F456 HydrophobicContact CE2-CG 4.03Å; Y426-F456 HydrophobicContact CG-CD2 4.32Å; Y426-F456 HydrophobicContact CG-CE2 4.41Å; Y426-F456 HydrophobicContact CG-CG 4.45Å
427S98.4Very high96.4Very high1 Ų139.9 Ų39.91%0.00722%0.216CC..EExtended strand (participates in β ladder)trans-113.8140.1164.4-610000109.3E420 P451 V452E420-S427 PolarHBondContact N-O 2.93Å; E420-S427 PolarHBondContact O-N 3.49Å; S427-P451 VanDerWaalsContact OG-CB 3.24Å; S427-P451 WeakPolarHBondContact OG-CB 3.36Å; S427-V452 WeakPolarHBondContact CA-O 3.44Å; S427-V452 WeakPolarHBondContact CB-O 3.38Å; S427-V452 PolarHBondContact OG-N 3.45Å; S427-V452 PolarHBondContact OG-O 3.47Å
428L98.3Very high96.5Very high0 Ų041.2 Ų41.20%022%0.224CC..EExtended strand (participates in β ladder)trans-108.9126.7-179.3-64.290.1000108.9I389 L391 F417 T418 L419 Y435 W436 F454 F456I389-L428 HydrophobicContact CG2-CD2 4.13Å; L391-L428 HydrophobicContact CD1-CD2 4.16Å; F417-L428 HydrophobicContact CB-CB 4.33Å; F417-L428 HydrophobicContact CB-CD2 4.39Å; T418-L428 WeakPolarHBondContact O-CA 3.32Å; L419-L428 HydrophobicContact CD1-CD1 4.34Å; L419-L428 HydrophobicContact CD1-CD2 4.39Å; L419-L428 HydrophobicContact CD1-CG 3.85Å; L428-Y435 CarbonylContact O-C 3.39Å; L428-Y435 VanDerWaalsContact O-CA 3.27Å; L428-Y435 WeakPolarHBondContact O-CA 3.49Å; L428-W436 HydrophobicContact CB-CB 4.25Å; L428-W436 HydrophobicContact CB-CD2 3.74Å; L428-W436 HydrophobicContact CB-CE3 4.29Å; L428-W436 HydrophobicContact CB-CG 3.72Å; L428-W436 HydrophobicContact CD1-CD2 4.46Å; L428-W436 HydrophobicContact CD1-CE3 4.16Å; L428-W436 HydrophobicContact CD2-CD2 4.13Å; L428-W436 HydrophobicContact CD2-CE3 4.05Å; L428-W436 HydrophobicContact CD2-CH2 3.89Å; L428-W436 HydrophobicContact CD2-CZ2 3.97Å; L428-W436 HydrophobicContact CD2-CZ3 3.93Å; L428-W436 HydrophobicContact CG-CD2 4.33Å; L428-W436 HydrophobicContact CG-CE3 4.4Å; L428-W436 PolarHBondContact O-N 3.24Å; L428-F454 HydrophobicContact CD1-CB 4.28Å; L428-F454 HydrophobicContact CD1-CD2 3.84Å; L428-F454 HydrophobicContact CD1-CG 4.21Å; L428-F456 HydrophobicContact CD1-CE1 4.31Å; L428-F456 HydrophobicContact CD1-CZ 4.38Å; L428-F456 HydrophobicContact CD2-CZ 4.45Å
429Q96.9Very high96.3Very high39 Ų3940.4 Ų40.418%0.18222%0.224CC..EExtended strand (participates in β ladder)trans-117.5133.8-179.7-165.3-176.853.600110.3F417 T418 G433 K434 Y435F417-Q429 CarbonylContact C-O 3.48Å; F417-Q429 VanDerWaalsContact CA-O 3.29Å; F417-Q429 WeakPolarHBondContact CA-O 3.41Å; T418-Q429 PolarHBondContact N-O 3.37Å; T418-Q429 PolarHBondContact O-N 2.88Å; Q429-G433 WeakPolarHBondContact CG-O 3.5Å; Q429-G433 PolarHBondContact NE2-O 3.43Å; Q429-K434 CarbonylContact C-O 3.43Å; Q429-K434 VanDerWaalsContact CA-O 3.31Å; Q429-K434 WeakPolarHBondContact CA-O 3.39Å; Q429-Y435 HydrophobicContact CB-CD1 3.82Å; Q429-Y435 HydrophobicContact CB-CE1 3.76Å; Q429-Y435 HydrophobicContact CG-CD1 4.17Å; Q429-Y435 HydrophobicContact CG-CE1 4.06Å; Q429-Y435 HydrophobicContact CG-CG 4.48Å; Q429-Y435 VanDerWaalsContact NE2-CZ 3.34Å; Q429-Y435 PolarHBondContact NE2-OH 2.9Å
430D94.8Very high95.9Very high13 Ų1346.7 Ų46.77%0.0726%0.258CS..  trans-79.8173.8172.971.925.2000112.7F417 T432 G433 K434 S446F417-D430 HydrophobicContact CD1-CB 4.15Å; F417-D430 HydrophobicContact CE1-CB 4.23Å; D430-T432 PolarHBondContact O-N 2.8Å; D430-T432 VanDerWaalsContact OD1-CA 3.31Å; D430-T432 WeakPolarHBondContact OD1-CA 3.26Å; D430-T432 WeakPolarHBondContact OD1-CB 3.44Å; D430-T432 PolarHBondContact OD1-N 2.88Å; D430-T432 PolarHBondContact OD1-OG1 2.94Å; D430-T432 PolarHBondContact OD2-OG1 2.89Å; D430-G433 PolarHBondContact O-N 3.31Å; D430-G433 PolarHBondContact OD1-N 2.71Å; D430-K434 PolarHBondContact N-O 2.74Å; D430-K434 PolarHBondContact OD1-N 3.34Å; D430-S446 WeakPolarHBondContact CB-OG 3.33Å; D430-S446 VanDerWaalsContact OD2-CB 3.3Å; D430-S446 WeakPolarHBondContact OD2-CB 3.37Å; D430-S446 PolarHBondContact OD2-OG 2.91Å
431S90.3Very high95.6Very high108 Ų10851.5 Ų51.576%0.75528%0.28SS*.THydrogen-bonded Turntrans-60.3-11.7178.763.30000115.6
432T92.1Very high95.5Very high106 Ų10651.8 Ų51.865%0.6528%0.282SS*.THydrogen-bonded Turntrans-94.6-3.9176.674.70000112.8D430D430-T432 PolarHBondContact O-N 2.8Å; D430-T432 VanDerWaalsContact OD1-CA 3.31Å; D430-T432 WeakPolarHBondContact OD1-CA 3.26Å; D430-T432 WeakPolarHBondContact OD1-CB 3.44Å; D430-T432 PolarHBondContact OD1-N 2.88Å; D430-T432 PolarHBondContact OD1-OG1 2.94Å; D430-T432 PolarHBondContact OD2-OG1 2.89Å
433G93.4Very high95.5Very high29 Ų2947 Ų4730%0.29927%0.268SS..SBendtrans89.15.5-177.200000114Q429 D430Q429-G433 WeakPolarHBondContact CG-O 3.5Å; Q429-G433 PolarHBondContact NE2-O 3.43Å; D430-G433 PolarHBondContact O-N 3.31Å; D430-G433 PolarHBondContact OD1-N 2.71Å
434K97Very high95.7Very high61 Ų6143.4 Ų43.427%0.26525%0.249SC..PPolyproline II helixtrans-87.2136.1178.4-64.7-59.8-172173.20110.9Q429 D430 S446 S448 D449Q429-K434 CarbonylContact C-O 3.43Å; Q429-K434 VanDerWaalsContact CA-O 3.31Å; Q429-K434 WeakPolarHBondContact CA-O 3.39Å; D430-K434 PolarHBondContact N-O 2.74Å; D430-K434 PolarHBondContact OD1-N 3.34Å; K434-S446 PolarHBondContact O-OG 2.91Å; K434-S446 VanDerWaalsContact O-OG 3.1Å; K434-S448 WeakPolarHBondContact CA-O 3.5Å; K434-D449 IonicContact NZ-OD1 3.28Å; K434-D449 PolarHBondContact NZ-OD1 2.76Å; K434-D449 IonicContact NZ-OD2 2.89Å; K434-D449 PolarHBondContact NZ-OD2 2.76Å
435Y98.3Very high95.7Very high23 Ų2344 Ų449%0.0925%0.251CS..EExtended strand (participates in β ladder)trans-85.4147.7175.9-65.6-82.7000111.3E420 L428 Q429 S447 S448 P451E420-Y435 VanDerWaalsContact CD-OH 3.23Å; E420-Y435 PolarHBondContact OE1-OH 2.66Å; E420-Y435 PolarHBondContact OE2-OH 3.37Å; E420-Y435 VanDerWaalsContact OE2-OH 3.12Å; L428-Y435 CarbonylContact O-C 3.39Å; L428-Y435 VanDerWaalsContact O-CA 3.27Å; L428-Y435 WeakPolarHBondContact O-CA 3.49Å; Q429-Y435 HydrophobicContact CB-CD1 3.82Å; Q429-Y435 HydrophobicContact CB-CE1 3.76Å; Q429-Y435 HydrophobicContact CG-CD1 4.17Å; Q429-Y435 HydrophobicContact CG-CE1 4.06Å; Q429-Y435 HydrophobicContact CG-CG 4.48Å; Q429-Y435 VanDerWaalsContact NE2-CZ 3.34Å; Q429-Y435 PolarHBondContact NE2-OH 2.9Å; Y435-S447 PolarHBondContact O-N 2.95Å; Y435-S447 VanDerWaalsContact O-N 3.08Å; Y435-S448 PolarHBondContact N-O 2.98Å; Y435-S448 WeakPolarHBondContact O-CB 3.4Å; Y435-S448 PolarHBondContact O-N 3.18Å; Y435-P451 HydrophobicContact CD1-CB 4.31Å; Y435-P451 HydrophobicContact CD1-CG 4.45Å; Y435-P451 HydrophobicContact CD2-CG 4.32Å; Y435-P451 HydrophobicContact CE1-CB 4.23Å; Y435-P451 HydrophobicContact CE1-CG 4.02Å; Y435-P451 HydrophobicContact CE2-CG 3.88Å
436W98.4Very high95.7Very high0 Ų044.3 Ų44.30%025%0.252CS..EExtended strand (participates in β ladder)trans-58.8141.6165.3-73.426.7000110.1L391 I398 L407 F417 L428 V444 V445 V452 F454 L475 L483L391-W436 HydrophobicContact CD1-CH2 3.87Å; L391-W436 HydrophobicContact CD1-CZ3 4.45Å; I398-W436 HydrophobicContact CD1-CH2 3.76Å; I398-W436 HydrophobicContact CG2-CH2 3.89Å; I398-W436 HydrophobicContact CG2-CZ2 3.84Å; L407-W436 HydrophobicContact CD1-CD2 3.45Å; L407-W436 VanDerWaalsContact CD1-CD2 3.45Å; L407-W436 HydrophobicContact CD1-CE3 3.92Å; L407-W436 HydrophobicContact CD1-CG 3.85Å; L407-W436 HydrophobicContact CD1-CH2 4.13Å; L407-W436 HydrophobicContact CD1-CZ2 3.69Å; L407-W436 HydrophobicContact CD1-CZ3 4.24Å; L407-W436 HydrophobicContact CD2-CZ2 4.4Å; F417-W436 AromaticContact CD1-CE2 3.89Å; F417-W436 HydrophobicContact CD1-CZ2 4.04Å; F417-W436 AromaticContact CD1-NE1 3.19Å; F417-W436 AromaticContact CD2-CZ2 3.77Å; F417-W436 HydrophobicContact CD2-CZ2 3.77Å; F417-W436 AromaticContact CE1-CE2 3.9Å; F417-W436 AromaticContact CE1-CZ2 3.9Å; F417-W436 HydrophobicContact CE1-CZ2 3.9Å; F417-W436 AromaticContact CE1-NE1 3.26Å; F417-W436 VanDerWaalsContact CE1-NE1 3.26Å; F417-W436 AromaticContact CE2-CZ2 3.64Å; F417-W436 HydrophobicContact CE2-CZ2 3.64Å; F417-W436 AromaticContact CG-CZ2 3.98Å; F417-W436 HydrophobicContact CG-CZ2 3.98Å; F417-W436 AromaticContact CG-NE1 3.85Å; F417-W436 AromaticContact CZ-CZ2 3.7Å; F417-W436 HydrophobicContact CZ-CZ2 3.7Å; F417-W436 AromaticContact CZ-NE1 3.98Å; L428-W436 HydrophobicContact CB-CB 4.25Å; L428-W436 HydrophobicContact CB-CD2 3.74Å; L428-W436 HydrophobicContact CB-CE3 4.29Å; L428-W436 HydrophobicContact CB-CG 3.72Å; L428-W436 HydrophobicContact CD1-CD2 4.46Å; L428-W436 HydrophobicContact CD1-CE3 4.16Å; L428-W436 HydrophobicContact CD2-CD2 4.13Å; L428-W436 HydrophobicContact CD2-CE3 4.05Å; L428-W436 HydrophobicContact CD2-CH2 3.89Å; L428-W436 HydrophobicContact CD2-CZ2 3.97Å; L428-W436 HydrophobicContact CD2-CZ3 3.93Å; L428-W436 HydrophobicContact CG-CD2 4.33Å; L428-W436 HydrophobicContact CG-CE3 4.4Å; L428-W436 PolarHBondContact O-N 3.24Å; W436-V444 HydrophobicContact CB-CG1 4.35Å; W436-V444 HydrophobicContact CD2-CG1 4.3Å; W436-V444 HydrophobicContact CE3-CG1 3.88Å; W436-V445 CarbonylContact C-O 3.59Å; W436-V445 WeakPolarHBondContact CA-O 3.38Å; W436-V452 VanDerWaalsContact O-CB 3.3Å; W436-V452 WeakPolarHBondContact O-CB 3.41Å; W436-V452 WeakPolarHBondContact O-CG2 3.36Å; W436-F454 HydrophobicContact CB-CE2 3.74Å; W436-F454 HydrophobicContact CB-CZ 4.07Å; W436-L475 HydrophobicContact CE3-CD1 4.39Å; W436-L475 HydrophobicContact CZ3-CD1 3.91Å; W436-L483 HydrophobicContact CE3-CD2 4.43Å; W436-L483 HydrophobicContact CH2-CD2 3.92Å; W436-L483 HydrophobicContact CZ3-CD2 3.75Å
437M97.9Very high95.6Very high57 Ų5746.4 Ų46.428%0.28127%0.268SS..EExtended strand (participates in β ladder)trans-148.7157.3172.861.5172.8-68.100110.2V444 V445 S447 V452M437-V444 WeakPolarHBondContact O-CA 3.42Å; M437-V445 HydrophobicContact CG-CG2 3.68Å; M437-V445 WeakPolarHBondContact CG-O 3.3Å; M437-V445 PolarHBondContact N-O 3.23Å; M437-V445 PolarHBondContact O-N 3.33Å; M437-V445 HydrophobicContact SD-CG2 4.32Å; M437-S447 PolarHBondContact SD-OG 2.86Å; M437-V452 HydrophobicContact CB-CG2 3.85Å
438V97.5Very high95.5Very high29 Ų2947.1 Ų47.118%0.17627%0.273CS..EExtended strand (participates in β ladder)trans-91.1114.9170.5-176.20000108.5F454 H468 A485V438-F454 HydrophobicContact CG2-CE1 4.3Å; V438-F454 HydrophobicContact CG2-CZ 4.41Å; V438-H468 HydrophobicContact CG2-CB 4.13Å; V438-A485 HydrophobicContact CG1-CB 4.13Å; V438-A485 HydrophobicContact CG2-CB 3.8Å
439G91.7Very high95.5Very high26 Ų2653 Ų5327%0.26830%0.304SS..  trans-98.7-155.5179.500000113Q442 A443G439-Q442 PolarHBondContact O-N 2.85Å; G439-A443 PolarHBondContact N-O 3.16Å
440N89.1Confident95.5Very high152 Ų15255.5 Ų55.581%0.81332%0.323SS*.G310 helixtrans-59.2148.8178.1-66.6-18.6000111.7Q442 A443N440-Q442 PolarHBondContact O-N 2.76Å; N440-Q442 VanDerWaalsContact O-N 3.1Å; N440-A443 WeakPolarHBondContact O-CB 3.17Å; N440-A443 PolarHBondContact O-N 3.05Å; N440-A443 VanDerWaalsContact O-N 3.09Å
441E91Very high95.6Very high160 Ų16056.8 Ų56.875%0.74833%0.331SS*.G310 helixtrans53.729-179.8-54.4-175.4174.900114.4A443 K484E441-A443 PolarHBondContact O-N 3.05Å; E441-K484 PolarHBondContact O-NZ 3.21Å; E441-K484 IonicContact OE2-NZ 2.82Å
442Q95.7Very high96Very high72 Ų7253 Ų5334%0.33630%0.304SS..G310 helixtrans62.517.3-178.4-58.7-63.7-13.900114.4G439 N440 D471 K484 A485 N486G439-Q442 PolarHBondContact O-N 2.85Å; N440-Q442 PolarHBondContact O-N 2.76Å; N440-Q442 VanDerWaalsContact O-N 3.1Å; Q442-D471 PolarHBondContact OE1-OD2 2.66Å; Q442-K484 CarbonylContact O-C 3.59Å; Q442-K484 WeakPolarHBondContact O-CA 3.39Å; Q442-K484 WeakPolarHBondContact O-CB 3.44Å; Q442-A485 WeakPolarHBondContact CB-O 3.5Å; Q442-A485 PolarHBondContact O-N 2.55Å; Q442-A485 PolarHBondContact OE1-O 3.09Å; Q442-N486 HydrophobicContact CB-CB 4.07Å; Q442-N486 HydrophobicContact CG-CB 4.35Å
443A96.9Very high96.3Very high18 Ų1849.6 Ų49.615%0.14928%0.282CS..BIsolated β-bridgetrans-71.2132.8177.300000111.1G439 N440 E441 V482G439-A443 PolarHBondContact N-O 3.16Å; N440-A443 WeakPolarHBondContact O-CB 3.17Å; N440-A443 PolarHBondContact O-N 3.05Å; N440-A443 VanDerWaalsContact O-N 3.09Å; E441-A443 PolarHBondContact O-N 3.05Å; A443-V482 HydrophobicContact CB-CG1 4.45Å
444V98Very high96.5Very high0 Ų048.2 Ų48.20%027%0.268CS..EExtended strand (participates in β ladder)trans-88.6125.2173.3-166.30000109L407 W436 M437 F454 L475 L483 A485L407-V444 HydrophobicContact CD1-CB 4.26Å; L407-V444 HydrophobicContact CD1-CG1 3.76Å; L407-V444 PolarHBondContact N-O 3.31Å; W436-V444 HydrophobicContact CB-CG1 4.35Å; W436-V444 HydrophobicContact CD2-CG1 4.3Å; W436-V444 HydrophobicContact CE3-CG1 3.88Å; M437-V444 WeakPolarHBondContact O-CA 3.42Å; V444-F454 HydrophobicContact CG1-CZ 4.27Å; V444-L475 HydrophobicContact CG2-CD1 4.42Å; V444-L475 HydrophobicContact CG2-CD2 3.71Å; V444-L483 HydrophobicContact CB-CB 4.3Å; V444-L483 HydrophobicContact CB-CD2 3.92Å; V444-L483 HydrophobicContact CB-CG 3.97Å; V444-L483 HydrophobicContact CG1-CD2 4.18Å; V444-L483 HydrophobicContact CG2-CD2 4.28Å; V444-L483 HydrophobicContact CG2-CG 3.99Å; V444-L483 PolarHBondContact N-O 3.04Å; V444-A485 HydrophobicContact CG2-CB 4.29Å
445V97.4Very high96.6Very high25 Ų2545.8 Ų45.815%0.15226%0.257CS..EExtended strand (participates in β ladder)trans-132.8145.3-178.1-61.60000110.4G405 W436 M437 S447G405-V445 CarbonylContact O-C 3.57Å; G405-V445 WeakPolarHBondContact O-CA 3.35Å; W436-V445 CarbonylContact C-O 3.59Å; W436-V445 WeakPolarHBondContact CA-O 3.38Å; M437-V445 HydrophobicContact CG-CG2 3.68Å; M437-V445 WeakPolarHBondContact CG-O 3.3Å; M437-V445 PolarHBondContact N-O 3.23Å; M437-V445 PolarHBondContact O-N 3.33Å; M437-V445 HydrophobicContact SD-CG2 4.32Å; V445-S447 WeakPolarHBondContact CG2-OG 3.24Å; V445-S447 PolarHBondContact O-N 2.99Å
446S97.3Very high96.6Very high5 Ų545 Ų454%0.03526%0.255CS..EExtended strand (participates in β ladder)trans-92.288172.6-166.90000109.5G405 D430 K434G405-S446 WeakPolarHBondContact CA-O 3.4Å; G405-S446 PolarHBondContact O-N 3.12Å; D430-S446 WeakPolarHBondContact CB-OG 3.33Å; D430-S446 VanDerWaalsContact OD2-CB 3.3Å; D430-S446 WeakPolarHBondContact OD2-CB 3.37Å; D430-S446 PolarHBondContact OD2-OG 2.91Å; K434-S446 PolarHBondContact O-OG 2.91Å; K434-S446 VanDerWaalsContact O-OG 3.1Å
447S96.4Very high96.5Very high51 Ų5145.3 Ų45.336%0.35726%0.256SS..EExtended strand (participates in β ladder)trans-151.1-6.3-175.364.10000114.8Y435 M437 V445Y435-S447 PolarHBondContact O-N 2.95Å; Y435-S447 VanDerWaalsContact O-N 3.08Å; M437-S447 PolarHBondContact SD-OG 2.86Å; V445-S447 WeakPolarHBondContact CG2-OG 3.24Å; V445-S447 PolarHBondContact O-N 2.99Å
448S97.2Very high96.3Very high15 Ų1542.9 Ų42.911%0.10524%0.244CC..EExtended strand (participates in β ladder)trans-76.4140.9-178.9-178.50000111.3K434 Y435 T450K434-S448 WeakPolarHBondContact CA-O 3.5Å; Y435-S448 PolarHBondContact N-O 2.98Å; Y435-S448 WeakPolarHBondContact O-CB 3.4Å; Y435-S448 PolarHBondContact O-N 3.18Å; S448-T450 VanDerWaalsContact C-N 3.34Å; S448-T450 WeakPolarHBondContact CB-O 3.4Å; S448-T450 PolarHBondContact OG-N 3.32Å; S448-T450 VanDerWaalsContact OG-N 3.11Å; S448-T450 PolarHBondContact OG-O 2.98Å; S448-T450 PolarHBondContact OG-OG1 3.27Å
449D97.4Very high95.9Very high124 Ų12442.6 Ų42.666%0.66324%0.243SC*.SBendtrans-84.4-13.2169.8-74.6-62.6000112.7K434K434-D449 IonicContact NZ-OD1 3.28Å; K434-D449 PolarHBondContact NZ-OD1 2.76Å; K434-D449 IonicContact NZ-OD2 2.89Å; K434-D449 PolarHBondContact NZ-OD2 2.76Å
450T97.4Very high95.9Very high92 Ų9242.4 Ų42.456%0.56424%0.236SC*.SBendtrans-117145.5179.656.10000111.6S448 V452S448-T450 VanDerWaalsContact C-N 3.34Å; S448-T450 WeakPolarHBondContact CB-O 3.4Å; S448-T450 PolarHBondContact OG-N 3.32Å; S448-T450 VanDerWaalsContact OG-N 3.11Å; S448-T450 PolarHBondContact OG-O 2.98Å; S448-T450 PolarHBondContact OG-OG1 3.27Å; T450-V452 PolarHBondContact O-N 2.78Å
451P97.8Very high95.7Very high39 Ų3938.9 Ų38.925%0.25321%0.211SC..  trans-60.1135.8177.5-23.834.8000112.2S427 Y435S427-P451 VanDerWaalsContact OG-CB 3.24Å; S427-P451 WeakPolarHBondContact OG-CB 3.36Å; Y435-P451 HydrophobicContact CD1-CB 4.31Å; Y435-P451 HydrophobicContact CD1-CG 4.45Å; Y435-P451 HydrophobicContact CD2-CG 4.32Å; Y435-P451 HydrophobicContact CE1-CB 4.23Å; Y435-P451 HydrophobicContact CE1-CG 4.02Å; Y435-P451 HydrophobicContact CE2-CG 3.88Å
452V98.1Very high95.3Very high30 Ų3031.6 Ų31.618%0.18218%0.178CC..  trans-114.7136172.7-179.30000108.7S427 W436 M437 T450 F454S427-V452 WeakPolarHBondContact CA-O 3.44Å; S427-V452 WeakPolarHBondContact CB-O 3.38Å; S427-V452 PolarHBondContact OG-N 3.45Å; S427-V452 PolarHBondContact OG-O 3.47Å; W436-V452 VanDerWaalsContact O-CB 3.3Å; W436-V452 WeakPolarHBondContact O-CB 3.41Å; W436-V452 WeakPolarHBondContact O-CG2 3.36Å; M437-V452 HydrophobicContact CB-CG2 3.85Å; T450-V452 PolarHBondContact O-N 2.78Å; V452-F454 HydrophobicContact CB-CE2 4.19Å; V452-F454 HydrophobicContact CG1-CE2 4.11Å; V452-F454 HydrophobicContact CG1-CZ 4.43Å; V452-F454 WeakPolarHBondContact O-CD2 3.37Å
453D98.3Very high95.3Very high34 Ų3431.3 Ų31.318%0.18218%0.175CC..  trans-82125-174.5-75.2-0.4000111.5K346 A425 A469K346-D453 VanDerWaalsContact CE-OD2 3.27Å; K346-D453 WeakPolarHBondContact CE-OD2 3.43Å; K346-D453 IonicContact NZ-OD2 2.7Å; K346-D453 PolarHBondContact NZ-OD2 3.19Å; A425-D453 HydrophobicContact CB-CB 3.79Å; D453-A469 HydrophobicContact CB-CB 3.68Å; D453-A469 WeakPolarHBondContact O-CB 3.39Å; D453-A469 PolarHBondContact O-N 3.16Å
454F98.6Very high95.2Very high0 Ų030.5 Ų30.50%017%0.168CC..EExtended strand (participates in β ladder)trans-118.7146.5166.7-63.9-90.2000109.7Y426 L428 W436 V438 V444 V452 V466 R467 H468 L475Y426-F454 PolarHBondContact N-O 2.91Å; Y426-F454 PolarHBondContact O-N 2.88Å; L428-F454 HydrophobicContact CD1-CB 4.28Å; L428-F454 HydrophobicContact CD1-CD2 3.84Å; L428-F454 HydrophobicContact CD1-CG 4.21Å; W436-F454 HydrophobicContact CB-CE2 3.74Å; W436-F454 HydrophobicContact CB-CZ 4.07Å; V438-F454 HydrophobicContact CG2-CE1 4.3Å; V438-F454 HydrophobicContact CG2-CZ 4.41Å; V444-F454 HydrophobicContact CG1-CZ 4.27Å; V452-F454 HydrophobicContact CB-CE2 4.19Å; V452-F454 HydrophobicContact CG1-CE2 4.11Å; V452-F454 HydrophobicContact CG1-CZ 4.43Å; V452-F454 WeakPolarHBondContact O-CD2 3.37Å; F454-V466 HydrophobicContact CB-CG1 3.87Å; F454-V466 HydrophobicContact CD1-CG1 3.87Å; F454-V466 HydrophobicContact CG-CG1 4.17Å; F454-R467 CarbonylContact C-O 3.55Å; F454-R467 WeakPolarHBondContact CA-O 3.17Å; F454-H468 HydrophobicContact CD1-CB 4.33Å; F454-H468 HydrophobicContact CE1-CB 4.23Å; F454-L475 HydrophobicContact CD1-CD1 4.32Å; F454-L475 HydrophobicContact CE1-CD1 4.23Å; F454-L475 HydrophobicContact CE1-CD2 4.22Å
455L98.4Very high95.2Very high10 Ų1030.5 Ų30.55%0.05217%0.168CC..EExtended strand (participates in β ladder)trans-105.9132.9179.1-51.9176.2000108.8K346 A425 V466 R467 A469K346-L455 HydrophobicContact CG-CD2 3.97Å; A425-L455 HydrophobicContact CB-CD2 3.98Å; L455-V466 WeakPolarHBondContact O-CA 3.24Å; L455-R467 HydrophobicContact CB-CB 4.36Å; L455-R467 PolarHBondContact N-O 2.9Å; L455-R467 PolarHBondContact O-N 3.1Å; L455-A469 HydrophobicContact CD1-CB 4.47Å; L455-A469 HydrophobicContact CD2-CB 4.31Å; L455-A469 HydrophobicContact CG-CB 4.13Å
456F97.9Very high95.2Very high7 Ų729.3 Ų29.33%0.03116%0.161CC..EExtended strand (participates in β ladder)trans-103.9123.8178.6-78.210.8000109.9W343 L383 I389 L419 Y426 L428 L464 V466W343-F456 VanDerWaalsContact CH2-O 3.23Å; W343-F456 WeakPolarHBondContact CH2-O 3.5Å; W343-F456 WeakPolarHBondContact CZ3-O 3.31Å; L383-F456 HydrophobicContact CD2-CD2 4.32Å; L383-F456 HydrophobicContact CD2-CE2 4.48Å; I389-F456 HydrophobicContact CD1-CE2 3.75Å; I389-F456 HydrophobicContact CD1-CZ 4.22Å; L419-F456 HydrophobicContact CD1-CE2 3.9Å; L419-F456 HydrophobicContact CD1-CZ 3.71Å; L419-F456 HydrophobicContact CD2-CE2 3.86Å; Y426-F456 HydrophobicContact CD2-CB 4.04Å; Y426-F456 HydrophobicContact CD2-CD1 4.1Å; Y426-F456 AromaticContact CD2-CD2 3.94Å; Y426-F456 HydrophobicContact CD2-CD2 3.94Å; Y426-F456 HydrophobicContact CD2-CE2 4.46Å; Y426-F456 AromaticContact CD2-CG 3.75Å; Y426-F456 HydrophobicContact CD2-CG 3.75Å; Y426-F456 HydrophobicContact CE2-CB 3.92Å; Y426-F456 HydrophobicContact CE2-CD2 4.08Å; Y426-F456 HydrophobicContact CE2-CG 4.03Å; Y426-F456 HydrophobicContact CG-CD2 4.32Å; Y426-F456 HydrophobicContact CG-CE2 4.41Å; Y426-F456 HydrophobicContact CG-CG 4.45Å; L428-F456 HydrophobicContact CD1-CE1 4.31Å; L428-F456 HydrophobicContact CD1-CZ 4.38Å; L428-F456 HydrophobicContact CD2-CZ 4.45Å; F456-L464 HydrophobicContact CB-CD2 4.43Å; F456-L464 HydrophobicContact CD1-CD1 4.24Å; F456-L464 HydrophobicContact CD2-CD1 4.43Å; F456-L464 HydrophobicContact CD2-CD2 3.63Å; F456-L464 HydrophobicContact CE2-CD2 3.99Å; F456-L464 HydrophobicContact CG-CD1 4.19Å; F456-L464 HydrophobicContact CG-CD2 4.07Å; F456-V466 HydrophobicContact CD1-CG1 4.17Å; F456-V466 HydrophobicContact CD1-CG2 4.08Å; F456-V466 HydrophobicContact CE1-CB 4.42Å; F456-V466 HydrophobicContact CE1-CG1 3.89Å; F456-V466 HydrophobicContact CE1-CG2 3.8Å
457E96.6Very high95.2Very high5 Ų531.5 Ų31.52%0.02317%0.169CC..EExtended strand (participates in β ladder)trans-117.4104.3-179-60.5-177-175.800109.7W343 C459 L464 A465 R467 Y474W343-E457 HydrophobicContact CB-CG 4.28Å; W343-E457 HydrophobicContact CD2-CB 3.98Å; W343-E457 HydrophobicContact CD2-CG 3.66Å; W343-E457 HydrophobicContact CE3-CG 4.07Å; W343-E457 HydrophobicContact CG-CB 4.21Å; W343-E457 HydrophobicContact CG-CG 3.72Å; W343-E457 VanDerWaalsContact CZ2-CA 3.43Å; W343-E457 HydrophobicContact CZ2-CB 4.09Å; E457-C459 PolarHBondContact O-N 3.45Å; E457-C459 VanDerWaalsContact O-N 3.09Å; E457-C459 PolarHBondContact O-SG 3.31Å; E457-L464 CarbonylContact O-C 3.47Å; E457-L464 WeakPolarHBondContact O-CA 3.37Å; E457-A465 HydrophobicContact CB-CB 4.39Å; E457-A465 PolarHBondContact N-O 2.86Å; E457-A465 PolarHBondContact O-N 2.88Å; E457-R467 IonicContact OE1-CZ 4Å; E457-R467 IonicContact OE1-NE 2.69Å; E457-R467 PolarHBondContact OE1-NE 3.39Å; E457-R467 IonicContact OE1-NH2 3.15Å; E457-R467 PolarHBondContact OE1-NH2 2.91Å; E457-Y474 WeakPolarHBondContact OE2-CE1 3.24Å; E457-Y474 PolarHBondContact OE2-OH 2.53Å
458F94.1Very high95.3Very high6 Ų630.3 Ų30.33%0.02616%0.158CC..EExtended strand (participates in β ladder)trans-71100.6174-58.9-75.8000110.4P264 V266 I301 W343 M381 L383 L464 Y498P264-F458 HydrophobicContact CB-CD1 4.27Å; P264-F458 HydrophobicContact CB-CE1 3.63Å; P264-F458 HydrophobicContact CB-CZ 4.03Å; P264-F458 HydrophobicContact CG-CD1 4.35Å; P264-F458 HydrophobicContact CG-CE1 4.2Å; V266-F458 HydrophobicContact CG1-CE2 4.25Å; V266-F458 HydrophobicContact CG1-CZ 4.49Å; I301-F458 HydrophobicContact CD1-CB 4.23Å; I301-F458 HydrophobicContact CG1-CB 4.28Å; W343-F458 AromaticContact CH2-CD2 3.9Å; W343-F458 HydrophobicContact CH2-CD2 3.9Å; W343-F458 HydrophobicContact CZ2-CB 4.26Å; W343-F458 HydrophobicContact CZ2-CD2 4.37Å; M381-F458 HydrophobicContact CE-CD2 3.45Å; M381-F458 VanDerWaalsContact CE-CD2 3.45Å; M381-F458 HydrophobicContact CE-CE2 3.66Å; M381-F458 HydrophobicContact SD-CD2 4.43Å; M381-F458 HydrophobicContact SD-CE2 4.41Å; L383-F458 HydrophobicContact CB-CZ 4.44Å; L383-F458 HydrophobicContact CD1-CZ 4.06Å; L383-F458 HydrophobicContact CD2-CZ 4.17Å; L383-F458 HydrophobicContact CG-CZ 4.46Å; F458-L464 HydrophobicContact CD1-CB 4.13Å; F458-L464 HydrophobicContact CE1-CB 4.47Å; F458-L464 HydrophobicContact CE1-CD2 4.15Å; F458-Y498 AromaticContact CD1-CE1 3.98Å; F458-Y498 HydrophobicContact CD1-CE1 3.98Å; F458-Y498 AromaticContact CD1-CZ 3.81Å; F458-Y498 WeakPolarHBondContact CD1-OH 3.3Å; F458-Y498 HydrophobicContact CE1-CE1 4.03Å; F458-Y498 HydrophobicContact CE1-CE2 4.18Å; F458-Y498 AromaticContact CE1-CZ 3.7Å
459C89.3Confident95.2Very high24 Ų2431.6 Ų31.616%0.16217%0.169CC..EExtended strand (participates in β ladder)trans-123-5.1-170.956.40000114.3E457 L490 L495E457-C459 PolarHBondContact O-N 3.45Å; E457-C459 VanDerWaalsContact O-N 3.09Å; E457-C459 PolarHBondContact O-SG 3.31Å; C459-L490 HydrophobicContact CB-CD1 4.23Å; C459-L495 WeakPolarHBondContact SG-CD2 3.3Å
460D90.1Very high95.1Very high22 Ų2228.9 Ų28.912%0.11817%0.17CC..EExtended strand (participates in β ladder)trans-146.7166.3175.2-158.1-28.1000110.5R306 N462 K463 L495R306-D460 IonicContact CZ-OD1 2.99Å; R306-D460 IonicContact CZ-OD2 2.73Å; R306-D460 VanDerWaalsContact CZ-OD2 3.29Å; R306-D460 IonicContact NH1-OD1 3.83Å; R306-D460 PolarHBondContact NH1-OD1 2.93Å; R306-D460 IonicContact NH1-OD2 2.87Å; R306-D460 PolarHBondContact NH1-OD2 2.81Å; R306-D460 VanDerWaalsContact NH2-CG 3.27Å; R306-D460 IonicContact NH2-OD1 3.79Å; R306-D460 IonicContact NH2-OD2 2.69Å; R306-D460 PolarHBondContact NH2-OD2 3.4Å; D460-N462 PolarHBondContact O-N 2.98Å; D460-N462 VanDerWaalsContact O-N 3.09Å; D460-K463 HydrophobicContact CB-CB 4.06Å; D460-K463 HydrophobicContact CB-CG 4.49Å; D460-K463 PolarHBondContact N-O 3.22Å; D460-K463 PolarHBondContact O-N 3.43Å; D460-K463 VanDerWaalsContact O-O 3.07Å; D460-L495 HydrophobicContact CB-CD1 4.23Å
461Y85.1Confident94.8Very high77 Ų7727.4 Ų27.430%0.30216%0.159SC..THydrogen-bonded Turntrans-57113172.9179.6-95.1000110.5H263 R303 K463H263-Y461 AromaticContact CE1-CE2 3.94Å; H263-Y461 AromaticContact CE1-CZ 3.89Å; R303-Y461 HydrophobicContact CG-CD2 4.48Å; R303-Y461 HydrophobicContact CG-CG 4.11Å; Y461-K463 PolarHBondContact O-N 3.06Å; Y461-K463 VanDerWaalsContact O-N 3.12Å
462N84.1Confident94.7Very high7 Ų726.8 Ų26.84%0.03716%0.16CC..THydrogen-bonded Turntrans53.625.4-177.2-61.2-17.7000114.1Q261 H263 D460 E497Q261-N462 PolarHBondContact NE2-ND2 3.2Å; Q261-N462 PolarHBondContact OE1-ND2 3.44Å; H263-N462 PolarHBondContact CE1-OD1 2.76Å; H263-N462 PolarHBondContact ND1-OD1 2.74Å; D460-N462 PolarHBondContact O-N 2.98Å; D460-N462 VanDerWaalsContact O-N 3.09Å; N462-E497 VanDerWaalsContact O-CA 3.3Å; N462-E497 WeakPolarHBondContact O-CA 3.46Å; N462-E497 WeakPolarHBondContact O-CG 3.29Å
463K93.9Very high94.7Very high67 Ų6727.9 Ų27.929%0.29116%0.162SC..EExtended strand (participates in β ladder)trans-131.4147.5169.5-46.3180177.4179.50111.5D460 Y461 L495 W496 E497 Y498D460-K463 HydrophobicContact CB-CB 4.06Å; D460-K463 HydrophobicContact CB-CG 4.49Å; D460-K463 PolarHBondContact N-O 3.22Å; D460-K463 PolarHBondContact O-N 3.43Å; D460-K463 VanDerWaalsContact O-O 3.07Å; Y461-K463 PolarHBondContact O-N 3.06Å; Y461-K463 VanDerWaalsContact O-N 3.12Å; K463-L495 HydrophobicContact CB-CB 4.21Å; K463-L495 HydrophobicContact CD-CB 3.86Å; K463-L495 HydrophobicContact CD-CD1 4.33Å; K463-W496 CarbonylContact C-O 3.55Å; K463-W496 WeakPolarHBondContact CA-O 3.11Å; K463-W496 WeakPolarHBondContact CB-O 3.2Å; K463-E497 HydrophobicContact CG-CB 4.25Å; K463-Y498 VanDerWaalsContact C-CE1 3.46Å
464L95.7Very high94.7Very high0 Ų027.6 Ų27.60%016%0.158CC..EExtended strand (participates in β ladder)trans-123.1156.2173.563.682.5000109.3F456 E457 F458 V466 W496 Y498F456-L464 HydrophobicContact CB-CD2 4.43Å; F456-L464 HydrophobicContact CD1-CD1 4.24Å; F456-L464 HydrophobicContact CD2-CD1 4.43Å; F456-L464 HydrophobicContact CD2-CD2 3.63Å; F456-L464 HydrophobicContact CE2-CD2 3.99Å; F456-L464 HydrophobicContact CG-CD1 4.19Å; F456-L464 HydrophobicContact CG-CD2 4.07Å; E457-L464 CarbonylContact O-C 3.47Å; E457-L464 WeakPolarHBondContact O-CA 3.37Å; F458-L464 HydrophobicContact CD1-CB 4.13Å; F458-L464 HydrophobicContact CE1-CB 4.47Å; F458-L464 HydrophobicContact CE1-CD2 4.15Å; L464-V466 HydrophobicContact CD1-CB 4.46Å; L464-V466 HydrophobicContact CD1-CG2 3.29Å; L464-W496 PolarHBondContact N-O 2.93Å; L464-W496 PolarHBondContact O-N 3.04Å; L464-Y498 HydrophobicContact CB-CD1 4.05Å; L464-Y498 HydrophobicContact CB-CE1 3.93Å; L464-Y498 HydrophobicContact CD2-CD1 3.42Å; L464-Y498 VanDerWaalsContact CD2-CD1 3.42Å; L464-Y498 HydrophobicContact CD2-CE1 3.88Å; L464-Y498 HydrophobicContact CD2-CG 3.88Å; L464-Y498 HydrophobicContact CG-CD1 3.58Å; L464-Y498 HydrophobicContact CG-CE1 3.99Å; L464-Y498 HydrophobicContact CG-CG 4.44Å
465A97.4Very high94.7Very high0 Ų027.6 Ų27.60%016%0.159CC..EExtended strand (participates in β ladder)trans-94.3142.716100000109.1E457 Y474 L490 L495E457-A465 HydrophobicContact CB-CB 4.39Å; E457-A465 PolarHBondContact N-O 2.86Å; E457-A465 PolarHBondContact O-N 2.88Å; A465-Y474 HydrophobicContact CB-CD1 3.74Å; A465-Y474 HydrophobicContact CB-CE1 3.8Å; A465-L490 HydrophobicContact CB-CD2 3.29Å; A465-L495 HydrophobicContact CB-CD2 4.39Å
466V98.2Very high94.6Very high1 Ų130.9 Ų30.91%0.00617%0.17CC..EExtended strand (participates in β ladder)trans-106.7124.9172.3-174.60000107.4F454 L455 F456 L464 Y474 L475F454-V466 HydrophobicContact CB-CG1 3.87Å; F454-V466 HydrophobicContact CD1-CG1 3.87Å; F454-V466 HydrophobicContact CG-CG1 4.17Å; L455-V466 WeakPolarHBondContact O-CA 3.24Å; F456-V466 HydrophobicContact CD1-CG1 4.17Å; F456-V466 HydrophobicContact CD1-CG2 4.08Å; F456-V466 HydrophobicContact CE1-CB 4.42Å; F456-V466 HydrophobicContact CE1-CG1 3.89Å; F456-V466 HydrophobicContact CE1-CG2 3.8Å; L464-V466 HydrophobicContact CD1-CB 4.46Å; L464-V466 HydrophobicContact CD1-CG2 3.29Å; V466-Y474 CarbonylContact O-C 3.49Å; V466-Y474 WeakPolarHBondContact O-CA 3.37Å; V466-L475 HydrophobicContact CB-CB 4.24Å; V466-L475 HydrophobicContact CB-CD1 3.77Å; V466-L475 HydrophobicContact CB-CG 3.83Å; V466-L475 HydrophobicContact CG1-CD1 3.49Å; V466-L475 VanDerWaalsContact CG1-CD1 3.49Å; V466-L475 HydrophobicContact CG1-CG 3.82Å; V466-L475 WeakPolarHBondContact O-CG 3.43Å; V466-L475 PolarHBondContact O-N 2.81Å
467R97.7Very high94.5Very high51 Ų5131.3 Ų31.319%0.19218%0.177CC..EExtended strand (participates in β ladder)trans-118.6131.9179.5-174.216262.2125.3-5.9110.1F454 L455 E457 A469 G472 K473 Y474F454-R467 CarbonylContact C-O 3.55Å; F454-R467 WeakPolarHBondContact CA-O 3.17Å; L455-R467 HydrophobicContact CB-CB 4.36Å; L455-R467 PolarHBondContact N-O 2.9Å; L455-R467 PolarHBondContact O-N 3.1Å; E457-R467 IonicContact OE1-CZ 4Å; E457-R467 IonicContact OE1-NE 2.69Å; E457-R467 PolarHBondContact OE1-NE 3.39Å; E457-R467 IonicContact OE1-NH2 3.15Å; E457-R467 PolarHBondContact OE1-NH2 2.91Å; R467-A469 PolarHBondContact O-N 3.26Å; R467-G472 WeakPolarHBondContact CD-O 3.48Å; R467-G472 WeakPolarHBondContact CG-O 3.41Å; R467-K473 WeakPolarHBondContact CA-O 3.36Å; R467-Y474 HydrophobicContact CB-CD1 3.8Å; R467-Y474 HydrophobicContact CB-CE1 3.86Å; R467-Y474 HydrophobicContact CG-CD1 4.25Å; R467-Y474 HydrophobicContact CG-CE1 4.25Å
468H97.7Very high94.3Very high26 Ų2632.8 Ų32.812%0.1219%0.185CC..EExtended strand (participates in β ladder)trans-70.3127.5174.3175.8-134.4000109.5V438 F454 G470 D471 G472 K473 A485V438-H468 HydrophobicContact CG2-CB 4.13Å; F454-H468 HydrophobicContact CD1-CB 4.33Å; F454-H468 HydrophobicContact CE1-CB 4.23Å; H468-G470 VanDerWaalsContact C-N 3.26Å; H468-G470 PolarHBondContact O-N 3.33Å; H468-D471 WeakPolarHBondContact CB-OD1 3.29Å; H468-D471 IonicContact CE1-OD2 3.29Å; H468-D471 IonicContact CG-OD1 3.43Å; H468-D471 IonicContact ND1-OD1 2.6Å; H468-D471 PolarHBondContact ND1-OD1 3.4Å; H468-D471 IonicContact ND1-OD2 2.7Å; H468-D471 PolarHBondContact ND1-OD2 2.68Å; H468-G472 VanDerWaalsContact O-CA 3.28Å; H468-G472 WeakPolarHBondContact O-CA 3.35Å; H468-G472 PolarHBondContact O-N 2.8Å; H468-K473 PolarHBondContact N-O 3.29Å; H468-A485 HydrophobicContact CB-CB 4.14Å
469A96.3Very high94Very high41 Ų4141.6 Ų41.634%0.33923%0.226SC..THydrogen-bonded Turntrans-69.5-25.5-174.900000112.9D453 L455 R467D453-A469 HydrophobicContact CB-CB 3.68Å; D453-A469 WeakPolarHBondContact O-CB 3.39Å; D453-A469 PolarHBondContact O-N 3.16Å; L455-A469 HydrophobicContact CD1-CB 4.47Å; L455-A469 HydrophobicContact CD2-CB 4.31Å; L455-A469 HydrophobicContact CG-CB 4.13Å; R467-A469 PolarHBondContact O-N 3.26Å
470G93.6Very high94.1Very high67 Ų6743 Ų4369%0.69124%0.238SC*.THydrogen-bonded Turntrans-74.7-40.4-17500000114.7H468H468-G470 VanDerWaalsContact C-N 3.26Å; H468-G470 PolarHBondContact O-N 3.33Å
471D92.6Very high94.2Very high61 Ų6142.1 Ų42.133%0.32624%0.235SC..THydrogen-bonded Turntrans-119.8-4.5-177.15726.2000113.9Q442 H468 K473Q442-D471 PolarHBondContact OE1-OD2 2.66Å; H468-D471 WeakPolarHBondContact CB-OD1 3.29Å; H468-D471 IonicContact CE1-OD2 3.29Å; H468-D471 IonicContact CG-OD1 3.43Å; H468-D471 IonicContact ND1-OD1 2.6Å; H468-D471 PolarHBondContact ND1-OD1 3.4Å; H468-D471 IonicContact ND1-OD2 2.7Å; H468-D471 PolarHBondContact ND1-OD2 2.68Å; D471-K473 VanDerWaalsContact C-N 3.26Å; D471-K473 HydrophobicContact CB-CG 4.34Å; D471-K473 PolarHBondContact O-N 2.79Å; D471-K473 WeakPolarHBondContact OD1-CB 3.46Å; D471-K473 PolarHBondContact OD1-N 3.13Å
472G95.6Very high94.7Very high26 Ų2639.6 Ų39.627%0.26823%0.227SC..  trans71.714.4179.300000114.4R467 H468R467-G472 WeakPolarHBondContact CD-O 3.48Å; R467-G472 WeakPolarHBondContact CG-O 3.41Å; H468-G472 VanDerWaalsContact O-CA 3.28Å; H468-G472 WeakPolarHBondContact O-CA 3.35Å; H468-G472 PolarHBondContact O-N 2.8Å
473K97.7Very high95.4Very high54 Ų5439.2 Ų39.224%0.23523%0.226CC..PPolyproline II helixtrans-85.6139.1179.8-61.1-64.3-174.1174.50112.1R467 H468 D471 A485 A487 D488R467-K473 WeakPolarHBondContact CA-O 3.36Å; H468-K473 PolarHBondContact N-O 3.29Å; D471-K473 VanDerWaalsContact C-N 3.26Å; D471-K473 HydrophobicContact CB-CG 4.34Å; D471-K473 PolarHBondContact O-N 2.79Å; D471-K473 WeakPolarHBondContact OD1-CB 3.46Å; D471-K473 PolarHBondContact OD1-N 3.13Å; K473-A485 VanDerWaalsContact CB-C 3.47Å; K473-A485 HydrophobicContact CB-CB 4.35Å; K473-A485 VanDerWaalsContact CB-O 3.28Å; K473-A485 WeakPolarHBondContact CB-O 3.42Å; K473-A487 CarbonylContact C-O 3.56Å; K473-A487 WeakPolarHBondContact CA-O 3.42Å; K473-D488 IonicContact NZ-OD1 3.11Å; K473-D488 PolarHBondContact NZ-OD1 2.79Å; K473-D488 IonicContact NZ-OD2 3.58Å; K473-D488 PolarHBondContact NZ-OD2 3.46Å
474Y98.4Very high95.5Very high27 Ų2737.5 Ų37.511%0.10622%0.218CC..EExtended strand (participates in β ladder)trans-75.6145.5172.6-66.6-75.6000111.4E457 A465 V466 R467 N486 A487 L490E457-Y474 WeakPolarHBondContact OE2-CE1 3.24Å; E457-Y474 PolarHBondContact OE2-OH 2.53Å; A465-Y474 HydrophobicContact CB-CD1 3.74Å; A465-Y474 HydrophobicContact CB-CE1 3.8Å; V466-Y474 CarbonylContact O-C 3.49Å; V466-Y474 WeakPolarHBondContact O-CA 3.37Å; R467-Y474 HydrophobicContact CB-CD1 3.8Å; R467-Y474 HydrophobicContact CB-CE1 3.86Å; R467-Y474 HydrophobicContact CG-CD1 4.25Å; R467-Y474 HydrophobicContact CG-CE1 4.25Å; Y474-N486 PolarHBondContact O-N 2.95Å; Y474-A487 PolarHBondContact N-O 3.39Å; Y474-A487 PolarHBondContact O-N 2.91Å; Y474-L490 HydrophobicContact CD1-CD2 3.86Å; Y474-L490 HydrophobicContact CD2-CD2 4.43Å; Y474-L490 HydrophobicContact CE1-CD2 3.5Å; Y474-L490 VanDerWaalsContact CE1-CD2 3.5Å; Y474-L490 HydrophobicContact CE1-CG 4.3Å; Y474-L490 HydrophobicContact CE2-CD2 4.13Å; Y474-L490 HydrophobicContact CE2-CG 4.21Å; Y474-L490 HydrophobicContact CG-CD2 4.3Å
475L98.3Very high95.6Very high1 Ų137.5 Ų37.51%0.00522%0.218CC..EExtended strand (participates in β ladder)trans-77.5131.4175.2-57.6-163.4000110.7W436 V444 F454 V466 L483 K484 A485 T494 W496W436-L475 HydrophobicContact CE3-CD1 4.39Å; W436-L475 HydrophobicContact CZ3-CD1 3.91Å; V444-L475 HydrophobicContact CG2-CD1 4.42Å; V444-L475 HydrophobicContact CG2-CD2 3.71Å; F454-L475 HydrophobicContact CD1-CD1 4.32Å; F454-L475 HydrophobicContact CE1-CD1 4.23Å; F454-L475 HydrophobicContact CE1-CD2 4.22Å; V466-L475 HydrophobicContact CB-CB 4.24Å; V466-L475 HydrophobicContact CB-CD1 3.77Å; V466-L475 HydrophobicContact CB-CG 3.83Å; V466-L475 HydrophobicContact CG1-CD1 3.49Å; V466-L475 VanDerWaalsContact CG1-CD1 3.49Å; V466-L475 HydrophobicContact CG1-CG 3.82Å; V466-L475 WeakPolarHBondContact O-CG 3.43Å; V466-L475 PolarHBondContact O-N 2.81Å; L475-L483 HydrophobicContact CB-CD1 4.14Å; L475-L483 HydrophobicContact CD1-CD2 4.23Å; L475-K484 CarbonylContact C-O 3.54Å; L475-K484 VanDerWaalsContact CA-O 3.29Å; L475-K484 WeakPolarHBondContact CA-O 3.41Å; L475-A485 HydrophobicContact CD2-CB 3.47Å; L475-A485 VanDerWaalsContact CD2-CB 3.47Å; L475-T494 VanDerWaalsContact O-CA 3.31Å; L475-T494 WeakPolarHBondContact O-CA 3.49Å; L475-W496 HydrophobicContact CB-CZ2 4.32Å; L475-W496 PolarHBondContact O-NE1 3.03Å; L475-W496 VanDerWaalsContact O-NE1 3.16Å
476R97Very high95.6Very high78 Ų7839.9 Ų39.929%0.29423%0.231SC..EExtended strand (participates in β ladder)trans-144.5158.8169.261.6172.1176.2-169.61.2111.5K484 N486 A487 E491 A493 T494R476-K484 PolarHBondContact N-O 3.01Å; R476-K484 PolarHBondContact O-N 3.44Å; R476-N486 WeakPolarHBondContact CG-OD1 3.41Å; R476-N486 PolarHBondContact NE-OD1 3Å; R476-N486 PolarHBondContact NH2-OD1 3.49Å; R476-A487 HydrophobicContact CG-CB 4.18Å; R476-E491 WeakPolarHBondContact CD-OE1 3.25Å; R476-E491 IonicContact CZ-OE1 2.74Å; R476-E491 IonicContact NE-OE1 3.46Å; R476-E491 IonicContact NH1-OE1 3.39Å; R476-E491 PolarHBondContact NH1-OE1 3.41Å; R476-A493 HydrophobicContact CB-CB 4.47Å; R476-A493 WeakPolarHBondContact CB-O 3.48Å; R476-T494 HydrophobicContact CB-CG2 3.97Å
477G94.9Very high95.5Very high16 Ų1640 Ų4017%0.16523%0.231CC..EExtended strand (participates in β ladder)trans-75.8139.6167.600000111.6S409 V482S409-G477 WeakPolarHBondContact OG-CA 3.31Å; G477-V482 CarbonylContact C-O 3.46Å; G477-V482 WeakPolarHBondContact CA-O 3.33Å
478D92.5Very high95.5Very high36 Ų3642.5 Ų42.519%0.19325%0.249CC..  trans-80.9-176.7168.977.66.6000112.5A480 G481 V482 K484D478-A480 PolarHBondContact O-N 3.4Å; D478-A480 WeakPolarHBondContact OD1-CA 3.44Å; D478-A480 WeakPolarHBondContact OD1-CB 3.33Å; D478-A480 PolarHBondContact OD1-N 2.81Å; D478-G481 WeakPolarHBondContact O-CA 3.48Å; D478-G481 PolarHBondContact O-N 3.39Å; D478-G481 PolarHBondContact OD1-N 2.81Å; D478-V482 PolarHBondContact N-O 2.85Å; D478-V482 PolarHBondContact OD1-N 2.87Å; D478-K484 HydrophobicContact CB-CD 4.25Å; D478-K484 HydrophobicContact CB-CG 4.48Å; D478-K484 VanDerWaalsContact OD2-CE 3.31Å; D478-K484 WeakPolarHBondContact OD2-CE 3.45Å; D478-K484 IonicContact OD2-NZ 3.96Å
479H87.9Confident95.4Very high192 Ų19247.3 Ų47.389%0.88928%0.275SS*.THydrogen-bonded Turntrans-62.2-23.2-179.666.560000113.8
480A90.5Very high95.2Very high52 Ų5249.3 Ų49.343%0.4328%0.28SS..THydrogen-bonded Turntrans-90.9-7.7175.800000111.4N410 D478 V482N410-A480 PolarHBondContact ND2-O 2.92Å; N410-A480 VanDerWaalsContact ND2-O 3.14Å; D478-A480 PolarHBondContact O-N 3.4Å; D478-A480 WeakPolarHBondContact OD1-CA 3.44Å; D478-A480 WeakPolarHBondContact OD1-CB 3.33Å; D478-A480 PolarHBondContact OD1-N 2.81Å; A480-V482 HydrophobicContact CB-CG2 4.47Å
481G92.1Very high95.2Very high4 Ų449.9 Ų49.94%0.04127%0.265CS..  trans81.814.9-175.400000113.8D408 S409 D478D408-G481 CarbonylContact C-O 3.54Å; D408-G481 VanDerWaalsContact CA-O 3.23Å; D408-G481 WeakPolarHBondContact CA-O 3.36Å; S409-G481 PolarHBondContact N-O 2.99Å; S409-G481 PolarHBondContact OG-O 3.17Å; D478-G481 WeakPolarHBondContact O-CA 3.48Å; D478-G481 PolarHBondContact O-N 3.39Å; D478-G481 PolarHBondContact OD1-N 2.81Å
482V96.4Very high95.2Very high24 Ų2451.2 Ų51.215%0.14528%0.275CS..BIsolated β-bridgetrans-73.4133.6171.3178.70000108.5T406 A443 G477 D478 A480 K484T406-V482 HydrophobicContact CG2-CG1 4.11Å; A443-V482 HydrophobicContact CB-CG1 4.45Å; G477-V482 CarbonylContact C-O 3.46Å; G477-V482 WeakPolarHBondContact CA-O 3.33Å; D478-V482 PolarHBondContact N-O 2.85Å; D478-V482 PolarHBondContact OD1-N 2.87Å; A480-V482 HydrophobicContact CB-CG2 4.47Å; V482-K484 PolarHBondContact O-N 2.78Å
483L98.1Very high95.1Very high0 Ų051.2 Ų51.20%027%0.273CS..EExtended strand (participates in β ladder)trans-71.3127176.9-172.165.1000110.2I398 L407 W436 V444 L475 W496I398-L483 HydrophobicContact CD1-CD1 4.17Å; I398-L483 HydrophobicContact CD1-CD2 3.9Å; I398-L483 HydrophobicContact CG2-CD2 4.3Å; L407-L483 HydrophobicContact CB-CB 3.94Å; L407-L483 HydrophobicContact CB-CD2 3.99Å; L407-L483 HydrophobicContact CD1-CD2 3.89Å; L407-L483 WeakPolarHBondContact O-CB 3.43Å; L407-L483 PolarHBondContact O-N 3.02Å; W436-L483 HydrophobicContact CE3-CD2 4.43Å; W436-L483 HydrophobicContact CH2-CD2 3.92Å; W436-L483 HydrophobicContact CZ3-CD2 3.75Å; V444-L483 HydrophobicContact CB-CB 4.3Å; V444-L483 HydrophobicContact CB-CD2 3.92Å; V444-L483 HydrophobicContact CB-CG 3.97Å; V444-L483 HydrophobicContact CG1-CD2 4.18Å; V444-L483 HydrophobicContact CG2-CD2 4.28Å; V444-L483 HydrophobicContact CG2-CG 3.99Å; V444-L483 PolarHBondContact N-O 3.04Å; L475-L483 HydrophobicContact CB-CD1 4.14Å; L475-L483 HydrophobicContact CD1-CD2 4.23Å; L483-W496 HydrophobicContact CD1-CH2 3.45Å; L483-W496 VanDerWaalsContact CD1-CH2 3.45Å; L483-W496 HydrophobicContact CD1-CZ2 3.41Å; L483-W496 VanDerWaalsContact CD1-CZ2 3.41Å; L483-W496 HydrophobicContact CD1-CZ3 4.48Å
484K97.9Very high95.1Very high31 Ų3148.7 Ų48.714%0.13526%0.262CS..EExtended strand (participates in β ladder)trans-132.3146.1179.3-62.6-160.4170.8-164.90112.5E441 Q442 L475 R476 D478 V482 N486E441-K484 PolarHBondContact O-NZ 3.21Å; E441-K484 IonicContact OE2-NZ 2.82Å; Q442-K484 CarbonylContact O-C 3.59Å; Q442-K484 WeakPolarHBondContact O-CA 3.39Å; Q442-K484 WeakPolarHBondContact O-CB 3.44Å; L475-K484 CarbonylContact C-O 3.54Å; L475-K484 VanDerWaalsContact CA-O 3.29Å; L475-K484 WeakPolarHBondContact CA-O 3.41Å; R476-K484 PolarHBondContact N-O 3.01Å; R476-K484 PolarHBondContact O-N 3.44Å; D478-K484 HydrophobicContact CB-CD 4.25Å; D478-K484 HydrophobicContact CB-CG 4.48Å; D478-K484 VanDerWaalsContact OD2-CE 3.31Å; D478-K484 WeakPolarHBondContact OD2-CE 3.45Å; D478-K484 IonicContact OD2-NZ 3.96Å; V482-K484 PolarHBondContact O-N 2.78Å; K484-N486 HydrophobicContact CB-CB 4.49Å; K484-N486 PolarHBondContact O-N 2.8Å
485A97.6Very high95Very high0 Ų048.3 Ų48.30%026%0.261CS..EExtended strand (participates in β ladder)trans-95.275.7170.900000110V438 Q442 V444 H468 K473 L475V438-A485 HydrophobicContact CG1-CB 4.13Å; V438-A485 HydrophobicContact CG2-CB 3.8Å; Q442-A485 WeakPolarHBondContact CB-O 3.5Å; Q442-A485 PolarHBondContact O-N 2.55Å; Q442-A485 PolarHBondContact OE1-O 3.09Å; V444-A485 HydrophobicContact CG2-CB 4.29Å; H468-A485 HydrophobicContact CB-CB 4.14Å; K473-A485 VanDerWaalsContact CB-C 3.47Å; K473-A485 HydrophobicContact CB-CB 4.35Å; K473-A485 VanDerWaalsContact CB-O 3.28Å; K473-A485 WeakPolarHBondContact CB-O 3.42Å; L475-A485 HydrophobicContact CD2-CB 3.47Å; L475-A485 VanDerWaalsContact CD2-CB 3.47Å
486N96.6Very high94.9Very high49 Ų4948.4 Ų48.426%0.26226%0.262SS..EExtended strand (participates in β ladder)trans-143.610.2-171.571.30.7000115.3Q442 Y474 R476 K484Q442-N486 HydrophobicContact CB-CB 4.07Å; Q442-N486 HydrophobicContact CG-CB 4.35Å; Y474-N486 PolarHBondContact O-N 2.95Å; R476-N486 WeakPolarHBondContact CG-OD1 3.41Å; R476-N486 PolarHBondContact NE-OD1 3Å; R476-N486 PolarHBondContact NH2-OD1 3.49Å; K484-N486 HydrophobicContact CB-CB 4.49Å; K484-N486 PolarHBondContact O-N 2.8Å
487A97Very high94.8Very high3 Ų345.8 Ų45.83%0.02525%0.253CS..EExtended strand (participates in β ladder)trans-93.2137.5174.200000110.8K473 Y474 R476 T494K473-A487 CarbonylContact C-O 3.56Å; K473-A487 WeakPolarHBondContact CA-O 3.42Å; Y474-A487 PolarHBondContact N-O 3.39Å; Y474-A487 PolarHBondContact O-N 2.91Å; R476-A487 HydrophobicContact CG-CB 4.18Å; A487-T494 HydrophobicContact CB-CG2 3.49Å; A487-T494 VanDerWaalsContact CB-CG2 3.49Å
488D96.3Very high94.7Very high105 Ų10545.1 Ų45.156%0.56125%0.245SC*.SBendtrans-86.7-33.1177.1-79.6-76000112.6K473K473-D488 IonicContact NZ-OD1 3.11Å; K473-D488 PolarHBondContact NZ-OD1 2.79Å; K473-D488 IonicContact NZ-OD2 3.58Å; K473-D488 PolarHBondContact NZ-OD2 3.46Å
489D95.4Very high94.8Very high126 Ų12645.6 Ų45.667%0.67425%0.248SC*.SBendtrans-121.7161.1-172.5-63.1-66.8000111.6E491D489-E491 PolarHBondContact O-N 2.95Å
490L93.8Very high95.1Very high83 Ų8337.9 Ų37.944%0.43521%0.214SC..  trans-73.1121.8170.1-68.2175.9000110.4C459 A465 Y474C459-L490 HydrophobicContact CB-CD1 4.23Å; A465-L490 HydrophobicContact CB-CD2 3.29Å; Y474-L490 HydrophobicContact CD1-CD2 3.86Å; Y474-L490 HydrophobicContact CD2-CD2 4.43Å; Y474-L490 HydrophobicContact CE1-CD2 3.5Å; Y474-L490 VanDerWaalsContact CE1-CD2 3.5Å; Y474-L490 HydrophobicContact CE1-CG 4.3Å; Y474-L490 HydrophobicContact CE2-CD2 4.13Å; Y474-L490 HydrophobicContact CE2-CG 4.21Å; Y474-L490 HydrophobicContact CG-CD2 4.3Å
491E93.4Very high95.4Very high80 Ų8037.1 Ų37.137%0.37420%0.202SC..  trans-138167.7174.658.3-178.8176.900110.2R476 D489 A493 T494 L495R476-E491 WeakPolarHBondContact CD-OE1 3.25Å; R476-E491 IonicContact CZ-OE1 2.74Å; R476-E491 IonicContact NE-OE1 3.46Å; R476-E491 IonicContact NH1-OE1 3.39Å; R476-E491 PolarHBondContact NH1-OE1 3.41Å; D489-E491 PolarHBondContact O-N 2.95Å; E491-A493 HydrophobicContact CG-CB 4.25Å; E491-A493 PolarHBondContact O-N 2.9Å; E491-A493 VanDerWaalsContact O-N 3.09Å; E491-T494 HydrophobicContact CG-CG2 3.68Å; E491-T494 PolarHBondContact N-OG1 3.16Å; E491-T494 PolarHBondContact O-N 2.75Å; E491-T494 PolarHBondContact O-OG1 3.43Å; E491-L495 WeakPolarHBondContact O-CG 3.44Å
492T91.3Very high95.6Very high89 Ų8939.1 Ų39.155%0.54621%0.212SC..G310 helixtrans-53.1-36.4179.5-57.10000112.6T494 L495T492-T494 VanDerWaalsContact C-N 3.26Å; T492-T494 PolarHBondContact O-N 2.99Å; T492-L495 PolarHBondContact O-N 3.37Å
493A94.3Very high95.5Very high26 Ų2640 Ų4022%0.21522%0.216CC..G310 helixtrans-72.3-13.7-179.900000114.3R476 E491R476-A493 HydrophobicContact CB-CB 4.47Å; R476-A493 WeakPolarHBondContact CB-O 3.48Å; E491-A493 HydrophobicContact CG-CB 4.25Å; E491-A493 PolarHBondContact O-N 2.9Å; E491-A493 VanDerWaalsContact O-N 3.09Å
494T96.4Very high95.3Very high0 Ų042.7 Ų42.70%023%0.23CC..G310 helixtrans-99.22.2176.363.60000113.2L475 R476 A487 E491 T492 W496L475-T494 VanDerWaalsContact O-CA 3.31Å; L475-T494 WeakPolarHBondContact O-CA 3.49Å; R476-T494 HydrophobicContact CB-CG2 3.97Å; A487-T494 HydrophobicContact CB-CG2 3.49Å; A487-T494 VanDerWaalsContact CB-CG2 3.49Å; E491-T494 HydrophobicContact CG-CG2 3.68Å; E491-T494 PolarHBondContact N-OG1 3.16Å; E491-T494 PolarHBondContact O-N 2.75Å; E491-T494 PolarHBondContact O-OG1 3.43Å; T492-T494 VanDerWaalsContact C-N 3.26Å; T492-T494 PolarHBondContact O-N 2.99Å; T494-W496 VanDerWaalsContact O-CD1 3.26Å; T494-W496 PolarHBondContact O-NE1 3.34Å
495L96.6Very high95.2Very high19 Ų1943.5 Ų43.510%0.09924%0.237CC..EExtended strand (participates in β ladder)trans-98130.5-179.8-59.1-176.6000111.4C459 D460 K463 A465 E491 T492C459-L495 WeakPolarHBondContact SG-CD2 3.3Å; D460-L495 HydrophobicContact CB-CD1 4.23Å; K463-L495 HydrophobicContact CB-CB 4.21Å; K463-L495 HydrophobicContact CD-CB 3.86Å; K463-L495 HydrophobicContact CD-CD1 4.33Å; A465-L495 HydrophobicContact CB-CD2 4.39Å; E491-L495 WeakPolarHBondContact O-CG 3.44Å; T492-L495 PolarHBondContact O-N 3.37Å
496W97.1Very high95Very high3 Ų346.8 Ų46.81%0.01126%0.256CS..EExtended strand (participates in β ladder)trans-121.3119.3-177.1-52.592.2000109.3L391 R392 I398 S409 K463 L464 L475 L483 T494L391-W496 HydrophobicContact CB-CB 4.47Å; L391-W496 HydrophobicContact CD2-CB 3.96Å; R392-W496 CarbonylContact O-C 3.58Å; R392-W496 WeakPolarHBondContact O-CA 3.26Å; I398-W496 HydrophobicContact CD1-CD2 4.1Å; I398-W496 HydrophobicContact CD1-CE3 3.61Å; I398-W496 HydrophobicContact CD1-CH2 3.96Å; I398-W496 HydrophobicContact CD1-CZ2 4.39Å; I398-W496 HydrophobicContact CD1-CZ3 3.55Å; I398-W496 HydrophobicContact CG1-CE3 3.89Å; I398-W496 HydrophobicContact CG1-CH2 4.18Å; I398-W496 HydrophobicContact CG1-CZ3 3.52Å; S409-W496 VanDerWaalsContact CB-CH2 3.49Å; K463-W496 CarbonylContact C-O 3.55Å; K463-W496 WeakPolarHBondContact CA-O 3.11Å; K463-W496 WeakPolarHBondContact CB-O 3.2Å; L464-W496 PolarHBondContact N-O 2.93Å; L464-W496 PolarHBondContact O-N 3.04Å; L475-W496 HydrophobicContact CB-CZ2 4.32Å; L475-W496 PolarHBondContact O-NE1 3.03Å; L475-W496 VanDerWaalsContact O-NE1 3.16Å; L483-W496 HydrophobicContact CD1-CH2 3.45Å; L483-W496 VanDerWaalsContact CD1-CH2 3.45Å; L483-W496 HydrophobicContact CD1-CZ2 3.41Å; L483-W496 VanDerWaalsContact CD1-CZ2 3.41Å; L483-W496 HydrophobicContact CD1-CZ3 4.48Å; T494-W496 VanDerWaalsContact O-CD1 3.26Å; T494-W496 PolarHBondContact O-NE1 3.34Å
497E95.1Very high94.8Very high24 Ų2446.7 Ų46.711%0.11226%0.255CS..EExtended strand (participates in β ladder)trans-71.1146.4165.6-178.2-179.2-16000110.3H143 Q261 L391 R392 N462 K463H143-E497 HydrophobicContact CB-CG 4.25Å; Q261-E497 PolarHBondContact NE2-OE1 3.28Å; L391-E497 CarbonylContact C-O 3.5Å; L391-E497 WeakPolarHBondContact CA-O 3.41Å; R392-E497 HydrophobicContact CB-CB 4.28Å; R392-E497 IonicContact CZ-OE2 3.63Å; R392-E497 PolarHBondContact N-O 3.24Å; R392-E497 IonicContact NE-OE2 2.67Å; R392-E497 PolarHBondContact NE-OE2 3.07Å; R392-E497 IonicContact NH2-OE1 3.31Å; R392-E497 IonicContact NH2-OE2 2.69Å; R392-E497 PolarHBondContact NH2-OE2 3.21Å; R392-E497 PolarHBondContact O-N 3.24Å; N462-E497 VanDerWaalsContact O-CA 3.3Å; N462-E497 WeakPolarHBondContact O-CA 3.46Å; N462-E497 WeakPolarHBondContact O-CG 3.29Å; K463-E497 HydrophobicContact CG-CB 4.25Å
498Y91.4Very high94.6Very high2 Ų250.6 Ų50.61%0.00828%0.276CS..  trans-142.40-172.559.9-94.3000113.2H143 Q145 P264 R386 V390 F458 K463 L464H143-Y498 PolarHBondContact CE1-O 2.84Å; H143-Y498 PolarHBondContact CE1-OXT 3.23Å; H143-Y498 PolarHBondContact ND1-O 3.16Å; H143-Y498 WeakPolarHBondContact NE2-CA 3.46Å; Q145-Y498 PolarHBondContact OE1-OXT 3.28Å; P264-Y498 HydrophobicContact CB-CE2 3.65Å; P264-Y498 VanDerWaalsContact CD-OH 3.24Å; P264-Y498 WeakPolarHBondContact CD-OH 3.27Å; P264-Y498 HydrophobicContact CG-CE2 3.95Å; P264-Y498 WeakPolarHBondContact CG-OH 3.24Å; R386-Y498 VanDerWaalsContact CZ-OXT 3.24Å; R386-Y498 PolarHBondContact NE-OXT 2.93Å; R386-Y498 PolarHBondContact NH2-O 2.88Å; R386-Y498 PolarHBondContact NH2-OXT 2.82Å; V390-Y498 WeakPolarHBondContact O-CA 3.25Å; F458-Y498 AromaticContact CD1-CE1 3.98Å; F458-Y498 HydrophobicContact CD1-CE1 3.98Å; F458-Y498 AromaticContact CD1-CZ 3.81Å; F458-Y498 WeakPolarHBondContact CD1-OH 3.3Å; F458-Y498 HydrophobicContact CE1-CE1 4.03Å; F458-Y498 HydrophobicContact CE1-CE2 4.18Å; F458-Y498 AromaticContact CE1-CZ 3.7Å; K463-Y498 VanDerWaalsContact C-CE1 3.46Å; L464-Y498 HydrophobicContact CB-CD1 4.05Å; L464-Y498 HydrophobicContact CB-CE1 3.93Å; L464-Y498 HydrophobicContact CD2-CD1 3.42Å; L464-Y498 VanDerWaalsContact CD2-CD1 3.42Å; L464-Y498 HydrophobicContact CD2-CE1 3.88Å; L464-Y498 HydrophobicContact CD2-CG 3.88Å; L464-Y498 HydrophobicContact CG-CD1 3.58Å; L464-Y498 HydrophobicContact CG-CE1 3.99Å; L464-Y498 HydrophobicContact CG-CG 4.44Å

Retrieved 498 of 498 residues in 94.4 ms (Link to these results)