A0A3Q0KDC4_SCHMA Loading...

Protein YIF1

Has a role in transport between endoplasmic reticulum and Golgi.

AlphaFold DB , UniProt , Accession A0A3Q0KDC4, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 283 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	42.1	Very low	46.1	Very low	224 Å²	224	122.2 Å²	122.2	100%	1.103	68%	0.683	S	S	*	*				0	121.5	0	-75.6	161.6	173.8	0	0	107.6	A3	M1-A3 PolarHBondContact O-N 2.98Å
2	C	48.6	Very low	45.6	Very low	35 Å²	35	125.5 Å²	125.5	24%	0.236	70%	0.698	C	S	.	*			trans	-95	89.2	175	-57.8	0	0	0	0	107.3	C255	C2-C255 HydrophobicContact CB-CB 4Å; C2-C255 VanDerWaalsContact SG-CB 3.57Å
3	A	51.7	Low	45.4	Very low	79 Å²	79	130.8 Å²	130.8	65%	0.653	70%	0.703	S	S	*	*			trans	-73.7	142.1	176.6	0	0	0	0	0	110.1	M1	M1-A3 PolarHBondContact O-N 2.98Å
4	Y	45.5	Very low	45.2	Very low	134 Å²	134	130.9 Å²	130.9	53%	0.525	71%	0.714	S	S	.	*			trans	-58.4	131.9	171.3	-121.6	-92.9	0	0	0	109.7	A250 Y251	Y4-A250 HydrophobicContact CE1-CB 4.42Å; Y4-Y251 HydrophobicContact CD2-CE1 4.21Å; Y4-Y251 HydrophobicContact CE2-CE1 4.11Å; Y4-Y251 AromaticContact CE2-CZ 3.73Å; Y4-Y251 WeakPolarHBondContact CE2-OH 3.27Å
5	H	49.6	Very low	44.9	Very low	148 Å²	148	134.2 Å²	134.2	69%	0.685	72%	0.723	S	S	*	*			trans	-82.2	115.5	161.2	-165.4	61.1	0	0	0	106.8	P7	H5-P7 VanDerWaalsContact O-CD 3.25Å; H5-P7 WeakPolarHBondContact O-CD 3.32Å
6	N	48.6	Very low	45	Very low	122 Å²	122	134.3 Å²	134.3	65%	0.652	73%	0.729	S	S	*	*			trans	-85.6	107.3	179	-173.6	5.2	0	0	0	108.9	G8	N6-G8 PolarHBondContact O-N 3.3Å
7	P	47	Very low	44.7	Very low	102 Å²	102	132.7 Å²	132.7	66%	0.662	73%	0.728	S	S	*	*	P	Polyproline II helix	trans	-76.6	122.5	167.9	7.7	11	0	0	0	107.8	H5 Y9	H5-P7 VanDerWaalsContact O-CD 3.25Å; H5-P7 WeakPolarHBondContact O-CD 3.32Å; P7-Y9 PolarHBondContact O-N 2.89Å
8	G	38.8	Very low	44.1	Very low	72 Å²	72	138.2 Å²	138.2	74%	0.742	74%	0.738	S	S	*	*	P	Polyproline II helix	trans	-48.2	127.7	-171.8	0	0	0	0	0	114.9	N6	N6-G8 PolarHBondContact O-N 3.3Å
9	Y	41.7	Very low	43.7	Very low	206 Å²	206	142 Å²	142	81%	0.808	74%	0.742	S	S	*	*	P	Polyproline II helix	trans	-69.1	136.2	168.3	-105.4	-97.1	0	0	0	111.1	P7	P7-Y9 PolarHBondContact O-N 2.89Å
10	P	52.3	Low	43.5	Very low	104 Å²	104	139.2 Å²	139.2	68%	0.675	74%	0.741	S	S	*	*	P	Polyproline II helix	trans	-76.5	160.5	155.6	30.9	-29.7	0	0	0	111.2
11	P	40.9	Very low	43.1	Very low	118 Å²	118	139.6 Å²	139.6	77%	0.766	74%	0.743	S	S	*	*	P	Polyproline II helix	trans	-86.3	144.8	-155.6	32.2	-33.7	0	0	0	116
12	N	40.8	Very low	42.9	Very low	162 Å²	162	138.4 Å²	138.4	87%	0.866	73%	0.732	S	S	*	*			trans	31.1	118.9	146.2	-88.5	-17.4	0	0	0	120.7
13	Y	42.4	Very low	42.5	Very low	194 Å²	194	145.3 Å²	145.3	76%	0.761	76%	0.761	S	S	*	*			trans	-117	140.1	143.5	23	-91	0	0	0	108.4
14	P	42.9	Very low	42.2	Very low	133 Å²	133	147.6 Å²	147.6	86%	0.864	77%	0.769	S	S	*	*	P	Polyproline II helix	trans	-80	124.3	-173.4	25.5	-22.1	0	0	0	111.9
15	E	40.9	Very low	41.8	Very low	180 Å²	180	148.5 Å²	148.5	84%	0.841	78%	0.783	S	S	*	*	P	Polyproline II helix	trans	-88.7	131.4	167.8	-70.1	-174.3	162.1	0	0	110.8
16	T	45.5	Very low	41.2	Very low	135 Å²	135	146.7 Å²	146.7	83%	0.828	79%	0.787	S	S	*	*	P	Polyproline II helix	trans	-86.9	130.4	168.9	40.8	0	0	0	0	110.1
17	P	41.1	Very low	40.7	Very low	108 Å²	108	149.5 Å²	149.5	70%	0.701	80%	0.796	S	S	*	*	P	Polyproline II helix	trans	-95.3	121.5	175.4	32.3	-26.3	0	0	0	110.9
18	Y	32.8	Very low	40.2	Very low	232 Å²	232	153.4 Å²	153.4	91%	0.91	81%	0.806	S	S	*	*			trans	-107.8	100.4	164.9	-122.5	-88.9	0	0	0	108.9
19	Y	36.5	Very low	40	Very low	210 Å²	210	160 Å²	160	82%	0.824	81%	0.809	S	S	*	*			trans	-91.8	114.7	165.7	-87.6	-91.4	0	0	0	108.7
20	A	39.5	Very low	40.2	Very low	86 Å²	86	156.9 Å²	156.9	71%	0.711	81%	0.806	S	S	*	*			trans	-92.6	109.5	164.3	0	0	0	0	0	108.7
21	N	35.9	Very low	40.2	Very low	147 Å²	147	156.8 Å²	156.8	79%	0.786	81%	0.805	S	S	*	*			trans	-69.1	125.1	169.5	-78.2	-58.3	0	0	0	109.8
22	F	38.4	Very low	40.5	Very low	200 Å²	200	155.8 Å²	155.8	88%	0.877	81%	0.806	S	S	*	*			trans	-112.7	103.9	160.4	-101.3	-90.8	0	0	0	108.5
23	Q	40.1	Very low	41	Very low	180 Å²	180	152.3 Å²	152.3	84%	0.841	80%	0.8	S	S	*	*			trans	-79.8	130.2	163.5	-82.4	176.9	-93.2	0	0	109.1
24	P	44.3	Very low	41.4	Very low	127 Å²	127	148.6 Å²	148.6	83%	0.825	80%	0.8	S	S	*	*			trans	-80.3	117.6	163.1	12	3.6	0	0	0	108.7	S26	P24-S26 PolarHBondContact O-N 3.49Å
25	N	38.5	Very low	41.4	Very low	153 Å²	153	154.2 Å²	154.2	82%	0.818	80%	0.804	S	S	*	*			trans	-79.6	107.1	173.7	-152.1	10.4	0	0	0	108.4	Q27	N25-Q27 PolarHBondContact O-N 3.1Å
26	S	36.8	Very low	41.5	Very low	110 Å²	110	152.1 Å²	152.1	77%	0.769	80%	0.803	S	S	*	*			trans	-82.1	105	169.5	49.8	0	0	0	0	108.9	P24	P24-S26 PolarHBondContact O-N 3.49Å
27	Q	38	Very low	41.3	Very low	181 Å²	181	153.7 Å²	153.7	85%	0.846	81%	0.807	S	S	*	*			trans	-82	115.9	165.5	-84.9	-161.9	-34.6	0	0	109.9	N25 Y29	N25-Q27 PolarHBondContact O-N 3.1Å; Q27-Y29 PolarHBondContact O-N 3.2Å
28	E	36.2	Very low	41.1	Very low	184 Å²	184	151.5 Å²	151.5	86%	0.86	80%	0.804	S	S	*	*			trans	-75	108.8	172.8	-143.4	163.4	154.7	0	0	108.7
29	Y	35.4	Very low	41.3	Very low	209 Å²	209	148 Å²	148	82%	0.82	80%	0.801	S	S	*	*			trans	-90.4	105.9	172.5	-172.6	-94.6	0	0	0	109	Q27 P31	Q27-Y29 PolarHBondContact O-N 3.2Å; Y29-P31 WeakPolarHBondContact O-CD 3.36Å
30	I	44.4	Very low	41.4	Very low	142 Å²	142	144.9 Å²	144.9	73%	0.728	80%	0.804	S	S	*	*	P	Polyproline II helix	trans	-81.1	119.7	171.7	-57.3	171.6	0	0	0	107.8	A32	I30-A32 PolarHBondContact O-N 3.08Å
31	P	52.6	Low	41.3	Very low	102 Å²	102	143.9 Å²	143.9	66%	0.662	80%	0.802	S	S	*	*	P	Polyproline II helix	trans	-76.7	120.6	175.5	-4.3	20.8	0	0	0	110.1	Y29 A33	Y29-P31 WeakPolarHBondContact O-CD 3.36Å; P31-A33 PolarHBondContact O-N 3.1Å
32	A	47.6	Very low	41.3	Very low	96 Å²	96	145.3 Å²	145.3	79%	0.793	81%	0.806	S	S	*	*	P	Polyproline II helix	trans	-71.8	119.5	168	0	0	0	0	0	109.8	I30	I30-A32 PolarHBondContact O-N 3.08Å
33	A	50.2	Low	41.4	Very low	89 Å²	89	140.2 Å²	140.2	74%	0.736	80%	0.795	S	S	*	*	P	Polyproline II helix	trans	-66.9	136.7	177.3	0	0	0	0	0	111.8	P31 R35	P31-A33 PolarHBondContact O-N 3.1Å; A33-R35 PolarHBondContact O-N 3.26Å
34	P	51.9	Low	41.7	Very low	116 Å²	116	140 Å²	140	75%	0.753	79%	0.792	S	S	*	*	P	Polyproline II helix	trans	-70	120.8	167.6	-10	25.3	0	0	0	109.6	T36	P34-T36 PolarHBondContact O-N 3.37Å; P34-T36 VanDerWaalsContact O-N 3.15Å
35	R	43.8	Very low	42.1	Very low	252 Å²	252	140.3 Å²	140.3	95%	0.951	79%	0.785	S	S	*	*			trans	-71.3	99.7	164	-74.5	-178.3	167.3	162.6	-2.9	108.3	A33	A33-R35 PolarHBondContact O-N 3.26Å
36	T	41.7	Very low	42.7	Very low	136 Å²	136	141.3 Å²	141.3	83%	0.834	79%	0.785	S	S	*	*			trans	-102.3	124.7	162.5	49	0	0	0	0	109.6	P34	P34-T36 PolarHBondContact O-N 3.37Å; P34-T36 VanDerWaalsContact O-N 3.15Å
37	N	40.6	Very low	43.4	Very low	168 Å²	168	142.8 Å²	142.8	90%	0.898	78%	0.784	S	S	*	*			trans	-89.4	141.2	-176	-160.6	10.2	0	0	0	108.3
38	G	37.2	Very low	44	Very low	62 Å²	62	141.3 Å²	141.3	64%	0.639	78%	0.777	S	S	*	*			trans	97.1	101.9	156.9	0	0	0	0	0	117.2
39	N	38.4	Very low	45	Very low	157 Å²	157	139.2 Å²	139.2	84%	0.84	77%	0.766	S	S	*	*			trans	65.5	144.6	136	-83.8	-7.1	0	0	0	121.6
40	T	38.6	Very low	46.2	Very low	146 Å²	146	135.4 Å²	135.4	90%	0.896	76%	0.758	S	S	*	*			trans	85.3	120.8	161.6	50.2	0	0	0	0	118.9
41	G	36.4	Very low	47.1	Very low	65 Å²	65	132.4 Å²	132.4	67%	0.67	75%	0.748	S	S	*	*			trans	109.3	59.9	141	0	0	0	0	0	116.9	S43	G41-S43 VanDerWaalsContact C-N 3.28Å; G41-S43 PolarHBondContact O-N 2.95Å
42	M	36.7	Very low	47.7	Very low	176 Å²	176	131.8 Å²	131.8	87%	0.867	74%	0.739	S	S	*	*			trans	-72.4	83.7	163.1	-153.1	-74.9	-83.3	0	0	108.9
43	S	40.3	Very low	48.9	Very low	93 Å²	93	132 Å²	132	65%	0.65	73%	0.726	S	S	*	*			trans	-170.3	61.1	174.8	56.2	0	0	0	0	112.7	G41	G41-S43 VanDerWaalsContact C-N 3.28Å; G41-S43 PolarHBondContact O-N 2.95Å
44	F	46.1	Very low	49.7	Very low	176 Å²	176	130.7 Å²	130.7	77%	0.772	72%	0.715	S	S	*	*			trans	-159.5	9.9	160.4	-123.5	-85.5	0	0	0	114.9	Q46	F44-Q46 VanDerWaalsContact C-N 3.33Å; F44-Q46 PolarHBondContact O-N 3.41Å
45	I	52.9	Low	50.9	Low	133 Å²	133	129.8 Å²	129.8	68%	0.682	71%	0.708	S	S	*	*	T	Hydrogen-bonded Turn	trans	-75	-12.1	-165.8	-68.9	-177.8	0	0	0	114.5
46	Q	50.8	Low	52.3	Low	174 Å²	174	125.8 Å²	125.8	81%	0.813	69%	0.692	S	S	*	*	T	Hydrogen-bonded Turn	trans	-95.3	-18.6	-168.3	-151.3	171.3	2.4	0	0	116.4	F44	F44-Q46 VanDerWaalsContact C-N 3.33Å; F44-Q46 PolarHBondContact O-N 3.41Å
47	N	51.2	Low	53.8	Low	141 Å²	141	126.3 Å²	126.3	75%	0.754	68%	0.68	S	S	*	*	S	Bend	trans	-113.6	-3.7	-171	-101.6	21.6	0	0	0	116.9
48	Q	52	Low	55.2	Low	151 Å²	151	120.1 Å²	120.1	71%	0.706	66%	0.656	S	S	*	*	S	Bend	trans	-113.2	-4.5	174.5	-73.9	-147.3	-46.8	0	0	114.4	I50 P51	Q48-I50 VanDerWaalsContact C-N 3.34Å; Q48-I50 PolarHBondContact O-N 3.14Å; Q48-P51 WeakPolarHBondContact O-CD 3.25Å
49	F	55.7	Low	56.9	Low	140 Å²	140	119.8 Å²	119.8	61%	0.614	64%	0.644	S	S	*	*	H	α-helix	trans	-72	-29.6	-178	-148	-92.7	0	0	0	112.7	L53	F49-L53 WeakPolarHBondContact O-CB 3.45Å; F49-L53 PolarHBondContact O-N 3.11Å
50	I	60.3	Low	58.7	Low	128 Å²	128	114.7 Å²	114.7	66%	0.656	62%	0.624	S	S	*	*	H	α-helix	trans	-77.1	-46.1	-174.3	-55	176.7	0	0	0	112.8	Q48 A54	Q48-I50 VanDerWaalsContact C-N 3.34Å; Q48-I50 PolarHBondContact O-N 3.14Å; I50-A54 VanDerWaalsContact O-CB 3.31Å; I50-A54 WeakPolarHBondContact O-CB 3.49Å; I50-A54 PolarHBondContact O-N 3.43Å
51	P	64.9	Low	60.1	Low	79 Å²	79	112.7 Å²	112.7	51%	0.513	61%	0.605	S	S	.	*	H	α-helix	trans	-64.8	-41.6	176.3	-18.8	30.9	0	0	0	112.2	Q48 A54 V55	Q48-P51 WeakPolarHBondContact O-CD 3.25Å; P51-A54 PolarHBondContact O-N 2.68Å; P51-V55 VanDerWaalsContact O-CG2 3.32Å; P51-V55 WeakPolarHBondContact O-CG2 3.29Å; P51-V55 PolarHBondContact O-N 3.23Å
52	D	64.9	Low	62.1	Low	90 Å²	90	116.7 Å²	116.7	48%	0.481	61%	0.605	S	S	.	*	H	α-helix	trans	-70.2	-37.1	-179.1	-164.3	40.5	0	0	0	111.5	V55 R56	D52-V55 PolarHBondContact O-N 3.24Å; D52-R56 WeakPolarHBondContact O-CB 3.32Å; D52-R56 VanDerWaalsContact O-CG 3.3Å; D52-R56 WeakPolarHBondContact O-CG 3.39Å; D52-R56 PolarHBondContact O-N 3.4Å; D52-R56 IonicContact OD2-NE 2.69Å
53	L	73.2	Confident	63.9	Low	100 Å²	100	112.6 Å²	112.6	52%	0.524	59%	0.586	S	S	.	*	H	α-helix	trans	-65.5	-39.9	171.8	-174.2	66.2	0	0	0	111.9	F49 R56 Y57	F49-L53 WeakPolarHBondContact O-CB 3.45Å; F49-L53 PolarHBondContact O-N 3.11Å; L53-R56 PolarHBondContact O-N 2.58Å; L53-Y57 VanDerWaalsContact O-CB 3.22Å; L53-Y57 WeakPolarHBondContact O-CB 3.08Å; L53-Y57 PolarHBondContact O-N 3.01Å
54	A	66.7	Low	65.4	Low	61 Å²	61	115 Å²	115	50%	0.504	59%	0.587	S	S	.	*	H	α-helix	trans	-66.5	-39.8	176.7	0	0	0	0	0	112.2	I50 P51 G58	I50-A54 VanDerWaalsContact O-CB 3.31Å; I50-A54 WeakPolarHBondContact O-CB 3.49Å; I50-A54 PolarHBondContact O-N 3.43Å; P51-A54 PolarHBondContact O-N 2.68Å; A54-G58 WeakPolarHBondContact O-CA 3.22Å; A54-G58 PolarHBondContact O-N 3.35Å
55	V	77.1	Confident	66.4	Low	98 Å²	98	108.1 Å²	108.1	59%	0.594	57%	0.566	S	S	*	*	H	α-helix	trans	-67.3	-43.2	174.7	172.8	0	0	0	0	110.7	P51 D52 G58 S59	P51-V55 VanDerWaalsContact O-CG2 3.32Å; P51-V55 WeakPolarHBondContact O-CG2 3.29Å; P51-V55 PolarHBondContact O-N 3.23Å; D52-V55 PolarHBondContact O-N 3.24Å; V55-G58 PolarHBondContact O-N 3.37Å; V55-S59 WeakPolarHBondContact O-CB 3.02Å; V55-S59 PolarHBondContact O-N 2.96Å; V55-S59 PolarHBondContact O-OG 3.09Å; V55-S59 VanDerWaalsContact O-OG 3.12Å
56	R	72.7	Confident	67.3	Low	167 Å²	167	103 Å²	103	63%	0.63	54%	0.544	S	S	*	.	H	α-helix	trans	-65.8	-41.2	177	-77.3	178.3	172.5	-128.2	-3.3	113.1	D52 L53 S59 A60	D52-R56 WeakPolarHBondContact O-CB 3.32Å; D52-R56 VanDerWaalsContact O-CG 3.3Å; D52-R56 WeakPolarHBondContact O-CG 3.39Å; D52-R56 PolarHBondContact O-N 3.4Å; D52-R56 IonicContact OD2-NE 2.69Å; L53-R56 PolarHBondContact O-N 2.58Å; R56-S59 WeakPolarHBondContact CA-OG 3.12Å; R56-S59 PolarHBondContact O-OG 2.93Å; R56-S59 VanDerWaalsContact O-OG 3.04Å; R56-A60 WeakPolarHBondContact O-CB 3.41Å; R56-A60 PolarHBondContact O-N 3.15Å
57	Y	73.3	Confident	68.2	Low	148 Å²	148	99.8 Å²	99.8	58%	0.58	53%	0.532	S	S	*	.	H	α-helix	trans	-70.7	-37.9	176.1	-170.9	-108.8	0	0	0	110.8	L53 A60 M61	L53-Y57 VanDerWaalsContact O-CB 3.22Å; L53-Y57 WeakPolarHBondContact O-CB 3.08Å; L53-Y57 PolarHBondContact O-N 3.01Å; Y57-A60 PolarHBondContact O-N 3.19Å; Y57-M61 HydrophobicContact CD1-CE 3.84Å; Y57-M61 HydrophobicContact CD1-CG 4.3Å; Y57-M61 HydrophobicContact CE1-CE 3.1Å; Y57-M61 HydrophobicContact CE1-CG 4.07Å; Y57-M61 HydrophobicContact CE1-SD 4Å; Y57-M61 HydrophobicContact CE2-CG 4.35Å; Y57-M61 VanDerWaalsContact O-CB 3.29Å; Y57-M61 WeakPolarHBondContact O-CB 3.22Å; Y57-M61 VanDerWaalsContact O-CG 3.28Å; Y57-M61 WeakPolarHBondContact O-CG 3.31Å; Y57-M61 PolarHBondContact O-N 3.36Å
58	G	69.3	Low	68.9	Low	38 Å²	38	99.5 Å²	99.5	39%	0.392	52%	0.524	S	S	.	.	H	α-helix	trans	-63.2	-43.8	173	0	0	0	0	0	112.6	A54 V55 F62	A54-G58 WeakPolarHBondContact O-CA 3.22Å; A54-G58 PolarHBondContact O-N 3.35Å; V55-G58 PolarHBondContact O-N 3.37Å; G58-F62 WeakPolarHBondContact O-CB 3.44Å; G58-F62 PolarHBondContact O-N 3.46Å
59	S	74.4	Confident	69.6	Low	55 Å²	55	95.9 Å²	95.9	39%	0.385	51%	0.512	S	S	.	.	H	α-helix	trans	-70.9	-39.6	175.8	65.7	0	0	0	0	111.7	V55 R56 F62 D63	V55-S59 WeakPolarHBondContact O-CB 3.02Å; V55-S59 PolarHBondContact O-N 2.96Å; V55-S59 PolarHBondContact O-OG 3.09Å; V55-S59 VanDerWaalsContact O-OG 3.12Å; R56-S59 WeakPolarHBondContact CA-OG 3.12Å; R56-S59 PolarHBondContact O-OG 2.93Å; R56-S59 VanDerWaalsContact O-OG 3.04Å; S59-F62 CarbonylContact O-C 3.46Å; S59-F62 PolarHBondContact O-N 3.3Å; S59-D63 WeakPolarHBondContact O-CB 3.48Å; S59-D63 VanDerWaalsContact O-CG 3.28Å; S59-D63 PolarHBondContact O-N 3.16Å
60	A	74.4	Confident	70	Confident	50 Å²	50	94.6 Å²	94.6	41%	0.413	51%	0.508	S	S	.	.	H	α-helix	trans	-64.5	-41.8	175.3	0	0	0	0	0	112	R56 Y57 D63 E64	R56-A60 WeakPolarHBondContact O-CB 3.41Å; R56-A60 PolarHBondContact O-N 3.15Å; Y57-A60 PolarHBondContact O-N 3.19Å; A60-D63 PolarHBondContact O-N 2.99Å; A60-E64 WeakPolarHBondContact O-CB 3.37Å; A60-E64 PolarHBondContact O-N 3.19Å
61	M	69.6	Low	70.2	Confident	103 Å²	103	96.5 Å²	96.5	51%	0.507	51%	0.511	S	S	.	.	H	α-helix	trans	-69.2	-32.7	173.2	-73.5	-127.8	-92.6	0	0	112.4	Y57 G65	Y57-M61 HydrophobicContact CD1-CE 3.84Å; Y57-M61 HydrophobicContact CD1-CG 4.3Å; Y57-M61 HydrophobicContact CE1-CE 3.1Å; Y57-M61 HydrophobicContact CE1-CG 4.07Å; Y57-M61 HydrophobicContact CE1-SD 4Å; Y57-M61 HydrophobicContact CE2-CG 4.35Å; Y57-M61 VanDerWaalsContact O-CB 3.29Å; Y57-M61 WeakPolarHBondContact O-CB 3.22Å; Y57-M61 VanDerWaalsContact O-CG 3.28Å; Y57-M61 WeakPolarHBondContact O-CG 3.31Å; Y57-M61 PolarHBondContact O-N 3.36Å; M61-G65 WeakPolarHBondContact O-CA 3.49Å; M61-G65 PolarHBondContact O-N 3.25Å
62	F	76.7	Confident	70	Confident	150 Å²	150	94.6 Å²	94.6	66%	0.658	50%	0.497	S	S	*	.	H	α-helix	trans	-68.6	-41.7	173.1	-177	-93.2	0	0	0	111.5	G58 S59 A66	G58-F62 WeakPolarHBondContact O-CB 3.44Å; G58-F62 PolarHBondContact O-N 3.46Å; S59-F62 CarbonylContact O-C 3.46Å; S59-F62 PolarHBondContact O-N 3.3Å; F62-A66 WeakPolarHBondContact O-CA 3.29Å; F62-A66 WeakPolarHBondContact O-CB 3.42Å; F62-A66 PolarHBondContact O-N 3.44Å
63	D	74.9	Confident	69.7	Low	89 Å²	89	93.5 Å²	93.5	48%	0.476	49%	0.493	S	S	.	.	H	α-helix	trans	-72.6	-40.1	178.3	-72.2	-23.3	0	0	0	111.5	S59 A60 A66 N67	S59-D63 WeakPolarHBondContact O-CB 3.48Å; S59-D63 VanDerWaalsContact O-CG 3.28Å; S59-D63 PolarHBondContact O-N 3.16Å; A60-D63 PolarHBondContact O-N 2.99Å; D63-A66 PolarHBondContact O-N 2.86Å; D63-N67 VanDerWaalsContact O-CB 3.24Å; D63-N67 WeakPolarHBondContact O-CB 3.26Å; D63-N67 PolarHBondContact O-N 3.28Å; D63-N67 PolarHBondContact O-ND2 3.08Å
64	E	72.5	Confident	68.9	Low	144 Å²	144	92.8 Å²	92.8	67%	0.673	49%	0.49	S	S	*	.	H	α-helix	trans	-68.4	-39.5	173.6	-171.2	164	-167.5	0	0	111.1	A60 N67 F68	A60-E64 WeakPolarHBondContact O-CB 3.37Å; A60-E64 PolarHBondContact O-N 3.19Å; E64-N67 PolarHBondContact O-N 2.89Å; E64-F68 VanDerWaalsContact O-CB 3.22Å; E64-F68 WeakPolarHBondContact O-CB 3.44Å; E64-F68 PolarHBondContact O-N 3.39Å
65	G	67.5	Low	68.4	Low	32 Å²	32	95.4 Å²	95.4	33%	0.33	49%	0.492	S	S	.	.	H	α-helix	trans	-63.3	-44.6	171.3	0	0	0	0	0	112.3	M61 F68 V69	M61-G65 WeakPolarHBondContact O-CA 3.49Å; M61-G65 PolarHBondContact O-N 3.25Å; G65-F68 PolarHBondContact O-N 3.29Å; G65-V69 WeakPolarHBondContact O-CB 3.34Å; G65-V69 WeakPolarHBondContact O-CG2 3.46Å; G65-V69 PolarHBondContact O-N 3.32Å
66	A	71.8	Confident	67.3	Low	26 Å²	26	99.8 Å²	99.8	22%	0.215	50%	0.499	C	S	.	.	H	α-helix	trans	-66.2	-39.5	177.1	0	0	0	0	0	111.3	F62 D63 H70	F62-A66 WeakPolarHBondContact O-CA 3.29Å; F62-A66 WeakPolarHBondContact O-CB 3.42Å; F62-A66 PolarHBondContact O-N 3.44Å; D63-A66 PolarHBondContact O-N 2.86Å; A66-H70 VanDerWaalsContact O-CB 3.26Å; A66-H70 WeakPolarHBondContact O-CB 3.21Å; A66-H70 PolarHBondContact O-N 2.8Å; A66-H70 PolarHBondContact O-ND1 3.19Å
67	N	69.1	Low	66.4	Low	105 Å²	105	94.8 Å²	94.8	56%	0.561	49%	0.487	S	S	*	.	H	α-helix	trans	-71.3	-37.5	175.7	-74	-39.1	0	0	0	112.2	D63 E64 K71	D63-N67 VanDerWaalsContact O-CB 3.24Å; D63-N67 WeakPolarHBondContact O-CB 3.26Å; D63-N67 PolarHBondContact O-N 3.28Å; D63-N67 PolarHBondContact O-ND2 3.08Å; E64-N67 PolarHBondContact O-N 2.89Å; N67-K71 WeakPolarHBondContact O-CB 3.15Å; N67-K71 PolarHBondContact O-N 2.94Å
68	F	65.1	Low	65.7	Low	136 Å²	136	90.9 Å²	90.9	60%	0.596	48%	0.476	S	S	*	.	H	α-helix	trans	-66.7	-42.4	173.6	-173	-91.7	0	0	0	111	E64 G65 N72	E64-F68 VanDerWaalsContact O-CB 3.22Å; E64-F68 WeakPolarHBondContact O-CB 3.44Å; E64-F68 PolarHBondContact O-N 3.39Å; G65-F68 PolarHBondContact O-N 3.29Å; F68-N72 VanDerWaalsContact CD2-ND2 3.29Å; F68-N72 WeakPolarHBondContact CD2-ND2 3.46Å; F68-N72 HydrophobicContact CE1-CB 4.45Å; F68-N72 VanDerWaalsContact CE2-ND2 3.26Å; F68-N72 WeakPolarHBondContact CE2-ND2 3.34Å; F68-N72 WeakPolarHBondContact CG-ND2 3.5Å; F68-N72 WeakPolarHBondContact CZ-ND2 3.5Å; F68-N72 WeakPolarHBondContact O-CB 3.46Å; F68-N72 PolarHBondContact O-N 3.45Å; F68-N72 PolarHBondContact O-ND2 3.41Å
69	V	67.8	Low	65.2	Low	75 Å²	75	98 Å²	98	46%	0.455	49%	0.491	S	S	.	.	H	α-helix	trans	-65.2	-47.9	174	168.5	0	0	0	0	109.9	G65 K71 N72 V73	G65-V69 WeakPolarHBondContact O-CB 3.34Å; G65-V69 WeakPolarHBondContact O-CG2 3.46Å; G65-V69 PolarHBondContact O-N 3.32Å; V69-K71 PolarHBondContact O-N 3.22Å; V69-N72 PolarHBondContact O-N 2.88Å; V69-V73 HydrophobicContact CB-CG2 4.38Å; V69-V73 HydrophobicContact CG1-CB 4.25Å; V69-V73 HydrophobicContact CG1-CG2 3.68Å; V69-V73 VanDerWaalsContact O-CA 3.29Å; V69-V73 WeakPolarHBondContact O-CA 3.38Å; V69-V73 WeakPolarHBondContact O-CB 3.47Å; V69-V73 WeakPolarHBondContact O-CG2 3.44Å; V69-V73 PolarHBondContact O-N 3.47Å
70	H	64	Low	64.5	Low	113 Å²	113	103.3 Å²	103.3	52%	0.523	51%	0.507	S	S	.	.	H	α-helix	trans	-61.4	-47.9	177.8	-73.7	165.8	0	0	0	111.7	A66 N72 D74	A66-H70 VanDerWaalsContact O-CB 3.26Å; A66-H70 WeakPolarHBondContact O-CB 3.21Å; A66-H70 PolarHBondContact O-N 2.8Å; A66-H70 PolarHBondContact O-ND1 3.19Å; H70-N72 PolarHBondContact O-N 2.88Å; H70-D74 WeakPolarHBondContact O-CB 3.34Å; H70-D74 VanDerWaalsContact O-CG 3.31Å; H70-D74 PolarHBondContact O-N 3.1Å
71	K	64.9	Low	64.2	Low	168 Å²	168	108.1 Å²	108.1	73%	0.73	52%	0.515	S	S	*	.	H	α-helix	trans	-68.6	-35.9	-178.3	-165.7	174.3	-179.3	178.9	0	113	N67 V69 Q75	N67-K71 WeakPolarHBondContact O-CB 3.15Å; N67-K71 PolarHBondContact O-N 2.94Å; V69-K71 PolarHBondContact O-N 3.22Å; K71-Q75 WeakPolarHBondContact O-CG 3.12Å
72	N	61.1	Low	64.5	Low	39 Å²	39	106.3 Å²	106.3	21%	0.209	51%	0.507	C	S	.	.	H	α-helix	trans	-91.2	-38.6	-178.9	-68.6	-83.8	0	0	0	113.2	F68 V69 H70 Q75 Y76	F68-N72 VanDerWaalsContact CD2-ND2 3.29Å; F68-N72 WeakPolarHBondContact CD2-ND2 3.46Å; F68-N72 HydrophobicContact CE1-CB 4.45Å; F68-N72 VanDerWaalsContact CE2-ND2 3.26Å; F68-N72 WeakPolarHBondContact CE2-ND2 3.34Å; F68-N72 WeakPolarHBondContact CG-ND2 3.5Å; F68-N72 WeakPolarHBondContact CZ-ND2 3.5Å; F68-N72 WeakPolarHBondContact O-CB 3.46Å; F68-N72 PolarHBondContact O-N 3.45Å; F68-N72 PolarHBondContact O-ND2 3.41Å; V69-N72 PolarHBondContact O-N 2.88Å; H70-N72 PolarHBondContact O-N 2.88Å; N72-Q75 WeakPolarHBondContact O-CG 3.38Å; N72-Q75 PolarHBondContact O-N 3.01Å; N72-Q75 PolarHBondContact OD1-NE2 2.93Å; N72-Y76 HydrophobicContact CB-CD2 4.41Å; N72-Y76 WeakPolarHBondContact O-CB 3.39Å; N72-Y76 WeakPolarHBondContact O-CD2 3.46Å; N72-Y76 PolarHBondContact O-N 2.89Å
73	V	58.2	Low	64.6	Low	66 Å²	66	106.6 Å²	106.6	40%	0.4	51%	0.508	S	S	.	.	H	α-helix	trans	-71.1	-35.2	177.5	-180	0	0	0	0	110.7	V69 Q75 Y76 V77	V69-V73 HydrophobicContact CB-CG2 4.38Å; V69-V73 HydrophobicContact CG1-CB 4.25Å; V69-V73 HydrophobicContact CG1-CG2 3.68Å; V69-V73 VanDerWaalsContact O-CA 3.29Å; V69-V73 WeakPolarHBondContact O-CA 3.38Å; V69-V73 WeakPolarHBondContact O-CB 3.47Å; V69-V73 WeakPolarHBondContact O-CG2 3.44Å; V69-V73 PolarHBondContact O-N 3.47Å; V73-Q75 VanDerWaalsContact C-N 3.27Å; V73-Q75 PolarHBondContact O-N 3.34Å; V73-Y76 PolarHBondContact O-N 3.12Å; V73-V77 HydrophobicContact CG1-CB 3.96Å; V73-V77 HydrophobicContact CG1-CG2 3.85Å; V73-V77 CarbonylContact O-C 3.59Å; V73-V77 VanDerWaalsContact O-CA 3.25Å; V73-V77 WeakPolarHBondContact O-CA 3.45Å; V73-V77 VanDerWaalsContact O-CB 3.24Å; V73-V77 WeakPolarHBondContact O-CB 3.41Å; V73-V77 PolarHBondContact O-N 3.49Å
74	D	55.4	Low	64.9	Low	85 Å²	85	105 Å²	105	46%	0.455	50%	0.495	S	S	.	.	H	α-helix	trans	-66.9	-29	175.2	-74.8	-28.1	0	0	0	112.6	H70 V77	H70-D74 WeakPolarHBondContact O-CB 3.34Å; H70-D74 VanDerWaalsContact O-CG 3.31Å; H70-D74 PolarHBondContact O-N 3.1Å; D74-V77 CarbonylContact O-C 3.59Å
75	Q	57.1	Low	65.4	Low	117 Å²	117	98.7 Å²	98.7	55%	0.547	47%	0.465	S	S	.	.	H	α-helix	trans	-79.7	-37.7	173.9	63.5	178.4	-1.5	0	0	113.4	K71 N72 V73	K71-Q75 WeakPolarHBondContact O-CG 3.12Å; N72-Q75 WeakPolarHBondContact O-CG 3.38Å; N72-Q75 PolarHBondContact O-N 3.01Å; N72-Q75 PolarHBondContact OD1-NE2 2.93Å; V73-Q75 VanDerWaalsContact C-N 3.27Å; V73-Q75 PolarHBondContact O-N 3.34Å
76	Y	53.3	Low	66.4	Low	190 Å²	190	101 Å²	101	75%	0.745	47%	0.467	S	S	*	.	H	α-helix	trans	-83.9	-31.6	-179.5	-78	-69.4	0	0	0	112.9	N72 V73	N72-Y76 HydrophobicContact CB-CD2 4.41Å; N72-Y76 WeakPolarHBondContact O-CB 3.39Å; N72-Y76 WeakPolarHBondContact O-CD2 3.46Å; N72-Y76 PolarHBondContact O-N 2.89Å; V73-Y76 PolarHBondContact O-N 3.12Å
77	V	54.6	Low	67	Low	62 Å²	62	102.4 Å²	102.4	38%	0.376	48%	0.475	S	S	.	.	S	Bend	trans	-113.1	71.5	173.5	-173.3	0	0	0	0	106.6	V73 D74 R79 I82	V73-V77 HydrophobicContact CG1-CB 3.96Å; V73-V77 HydrophobicContact CG1-CG2 3.85Å; V73-V77 CarbonylContact O-C 3.59Å; V73-V77 VanDerWaalsContact O-CA 3.25Å; V73-V77 WeakPolarHBondContact O-CA 3.45Å; V73-V77 VanDerWaalsContact O-CB 3.24Å; V73-V77 WeakPolarHBondContact O-CB 3.41Å; V73-V77 PolarHBondContact O-N 3.49Å; D74-V77 CarbonylContact O-C 3.59Å; V77-R79 VanDerWaalsContact C-N 3.28Å; V77-R79 PolarHBondContact O-N 3.04Å; V77-I82 HydrophobicContact CG1-CD1 3.42Å; V77-I82 VanDerWaalsContact CG1-CD1 3.42Å; V77-I82 HydrophobicContact CG1-CG1 4.26Å
78	N	57.3	Low	67.8	Low	66 Å²	66	98.7 Å²	98.7	35%	0.353	46%	0.456	S	S	.	.			trans	-56.9	99.2	170.9	-170	-16	0	0	0	107.4	F80 R81	N78-F80 PolarHBondContact O-N 3.16Å; N78-F80 WeakPolarHBondContact OD1-CD2 3.46Å; N78-R81 HydrophobicContact CB-CG 4.2Å; N78-R81 WeakPolarHBondContact O-CB 3.21Å; N78-R81 PolarHBondContact O-N 2.74Å
79	R	58.7	Low	68.9	Low	186 Å²	186	96.7 Å²	96.7	70%	0.702	45%	0.452	S	S	*	.	H	α-helix	trans	-51.9	-30.5	-170.5	-172	-179.3	-67	-136.2	1.5	111.4	V77 K83	V77-R79 VanDerWaalsContact C-N 3.28Å; V77-R79 PolarHBondContact O-N 3.04Å; R79-K83 WeakPolarHBondContact O-CB 3.16Å; R79-K83 PolarHBondContact O-N 3.02Å; R79-K83 VanDerWaalsContact O-N 3.1Å
80	F	60.7	Low	70.1	Confident	167 Å²	167	99.9 Å²	99.9	73%	0.732	47%	0.466	S	S	*	.	H	α-helix	trans	-63.3	-38.1	175.4	-64.4	-73.5	0	0	0	113.5	N78 Y84	N78-F80 PolarHBondContact O-N 3.16Å; N78-F80 WeakPolarHBondContact OD1-CD2 3.46Å; F80-Y84 PolarHBondContact O-N 3.22Å; F80-Y84 VanDerWaalsContact O-N 3.17Å
81	R	68.3	Low	71.3	Confident	151 Å²	151	98 Å²	98	57%	0.57	47%	0.465	S	S	*	.	H	α-helix	trans	-71.1	-43.5	179.5	-67.6	-167.7	-178.6	-160.8	1.8	111.9	N78 Y84 Y85	N78-R81 HydrophobicContact CB-CG 4.2Å; N78-R81 WeakPolarHBondContact O-CB 3.21Å; N78-R81 PolarHBondContact O-N 2.74Å; R81-Y84 WeakPolarHBondContact O-CB 3.11Å; R81-Y84 PolarHBondContact O-N 3.03Å; R81-Y85 WeakPolarHBondContact O-CD2 3.46Å; R81-Y85 WeakPolarHBondContact O-CE2 3.37Å
82	I	75.5	Confident	72.5	Confident	66 Å²	66	90.4 Å²	90.4	34%	0.338	43%	0.432	S	S	.	.	H	α-helix	trans	-65.1	-44.7	176.9	-64	-171.4	0	0	0	110.2	V77 Y84 Y85 F86 L193	V77-I82 HydrophobicContact CG1-CD1 3.42Å; V77-I82 VanDerWaalsContact CG1-CD1 3.42Å; V77-I82 HydrophobicContact CG1-CG1 4.26Å; I82-Y84 PolarHBondContact O-N 3.45Å; I82-Y84 VanDerWaalsContact O-N 3.17Å; I82-Y85 PolarHBondContact O-N 3.48Å; I82-F86 HydrophobicContact CG2-CD2 3.74Å; I82-F86 HydrophobicContact CG2-CE2 3.81Å; I82-F86 WeakPolarHBondContact O-CD2 3.32Å; I82-F86 PolarHBondContact O-N 3.19Å; I82-L193 HydrophobicContact CG1-CD1 4.25Å
83	K	79.7	Confident	74	Confident	155 Å²	155	89.7 Å²	89.7	67%	0.674	43%	0.429	S	S	*	.	H	α-helix	trans	-55.3	-36.4	178.1	-171.3	177.3	178.2	-176.3	0	112.3	R79 Y85 F86 S87	R79-K83 WeakPolarHBondContact O-CB 3.16Å; R79-K83 PolarHBondContact O-N 3.02Å; R79-K83 VanDerWaalsContact O-N 3.1Å; K83-Y85 PolarHBondContact O-N 3.34Å; K83-F86 PolarHBondContact O-N 3.42Å; K83-S87 WeakPolarHBondContact O-CB 3.35Å; K83-S87 PolarHBondContact O-N 2.81Å
84	Y	80.5	Confident	75.6	Confident	55 Å²	55	89.7 Å²	89.7	22%	0.216	44%	0.436	C	S	.	.	H	α-helix	trans	-55.8	-49.1	174.5	173.6	-88.9	0	0	0	112.6	F80 R81 I82 F86 S87 V119 P120 P121	F80-Y84 PolarHBondContact O-N 3.22Å; F80-Y84 VanDerWaalsContact O-N 3.17Å; R81-Y84 WeakPolarHBondContact O-CB 3.11Å; R81-Y84 PolarHBondContact O-N 3.03Å; I82-Y84 PolarHBondContact O-N 3.45Å; I82-Y84 VanDerWaalsContact O-N 3.17Å; Y84-F86 PolarHBondContact O-N 3.22Å; Y84-S87 PolarHBondContact O-N 2.97Å; Y84-V119 PolarHBondContact OH-O 2.93Å; Y84-P120 HydrophobicContact CD2-CB 4.2Å; Y84-P120 VanDerWaalsContact CE2-CA 3.42Å; Y84-P120 HydrophobicContact CE2-CB 4.15Å; Y84-P121 HydrophobicContact CE1-CG 4.34Å; Y84-P121 VanDerWaalsContact O-CD 3.24Å; Y84-P121 WeakPolarHBondContact O-CD 3.4Å
85	Y	83.5	Confident	77.3	Confident	12 Å²	12	91.7 Å²	91.7	5%	0.047	44%	0.441	C	S	.	.	H	α-helix	trans	-70.6	-17.1	-178.1	-67.5	-84.9	0	0	0	114.6	R81 I82 K83 P128 L130 S191 L193 D194	R81-Y85 WeakPolarHBondContact O-CD2 3.46Å; R81-Y85 WeakPolarHBondContact O-CE2 3.37Å; I82-Y85 PolarHBondContact O-N 3.48Å; K83-Y85 PolarHBondContact O-N 3.34Å; Y85-P128 HydrophobicContact CD1-CG 4.35Å; Y85-P128 HydrophobicContact CE1-CB 4.27Å; Y85-P128 HydrophobicContact CE1-CG 3.79Å; Y85-L130 HydrophobicContact CD1-CD1 4.26Å; Y85-L130 HydrophobicContact CD1-CG 4.1Å; Y85-L130 HydrophobicContact CD2-CD1 4.16Å; Y85-L130 HydrophobicContact CG-CD1 3.81Å; Y85-L130 HydrophobicContact CG-CG 4.02Å; Y85-L130 PolarHBondContact O-N 3.34Å; Y85-L130 VanDerWaalsContact O-N 3.1Å; Y85-S191 VanDerWaalsContact OH-CB 3.27Å; Y85-S191 WeakPolarHBondContact OH-CB 3.39Å; Y85-S191 PolarHBondContact OH-OG 3.47Å; Y85-L193 HydrophobicContact CD2-CB 4.08Å; Y85-L193 HydrophobicContact CD2-CD1 3.73Å; Y85-L193 HydrophobicContact CE1-CB 4.03Å; Y85-L193 HydrophobicContact CE2-CB 3.51Å; Y85-L193 HydrophobicContact CE2-CD1 3.42Å; Y85-L193 VanDerWaalsContact CE2-CD1 3.42Å; Y85-L193 HydrophobicContact CE2-CG 4.1Å; Y85-L193 VanDerWaalsContact CZ-CB 3.46Å; Y85-D194 WeakPolarHBondContact CE1-OD1 3.32Å; Y85-D194 VanDerWaalsContact CZ-OD1 3.25Å; Y85-D194 PolarHBondContact OH-OD1 3.35Å
86	F	86.8	Confident	79	Confident	81 Å²	81	86.1 Å²	86.1	36%	0.355	42%	0.415	S	S	.	.	H	α-helix	trans	-105	0.9	177.8	-73.3	-84.4	0	0	0	112.8	I82 K83 Y84 V88 L130 Y131 L134	I82-F86 HydrophobicContact CG2-CD2 3.74Å; I82-F86 HydrophobicContact CG2-CE2 3.81Å; I82-F86 WeakPolarHBondContact O-CD2 3.32Å; I82-F86 PolarHBondContact O-N 3.19Å; K83-F86 PolarHBondContact O-N 3.42Å; Y84-F86 PolarHBondContact O-N 3.22Å; F86-V88 PolarHBondContact O-N 2.92Å; F86-L130 HydrophobicContact CD2-CB 4.48Å; F86-L130 HydrophobicContact CE1-CB 4.42Å; F86-L130 HydrophobicContact CE2-CB 3.83Å; F86-L130 HydrophobicContact CE2-CD1 4.3Å; F86-L130 HydrophobicContact CZ-CB 3.79Å; F86-Y131 HydrophobicContact CD1-CD2 4.31Å; F86-L134 HydrophobicContact CE1-CD1 4.31Å; F86-L134 HydrophobicContact CZ-CD1 4.23Å
87	S	85.6	Confident	80.9	Confident	56 Å²	56	80 Å²	80	39%	0.392	39%	0.394	S	S	.	.			trans	-80.9	68.3	176.6	-171.5	0	0	0	0	110.7	K83 Y84 G122	K83-S87 WeakPolarHBondContact O-CB 3.35Å; K83-S87 PolarHBondContact O-N 2.81Å; Y84-S87 PolarHBondContact O-N 2.97Å; S87-G122 PolarHBondContact O-N 3.11Å
88	V	85.7	Confident	82.7	Confident	26 Å²	26	78.5 Å²	78.5	16%	0.158	39%	0.391	C	S	.	.			trans	-115.4	145.3	-177.5	-62.9	0	0	0	0	111.7	F86 Y92 V93 P121 D129 Y131	F86-V88 PolarHBondContact O-N 2.92Å; V88-Y92 HydrophobicContact CB-CD1 3.81Å; V88-Y92 HydrophobicContact CB-CE1 4.31Å; V88-Y92 HydrophobicContact CG1-CD1 3.66Å; V88-Y92 HydrophobicContact CG1-CE1 3.64Å; V88-V93 HydrophobicContact CB-CG2 4.3Å; V88-V93 HydrophobicContact CG2-CG2 4.18Å; V88-P121 HydrophobicContact CG1-CB 4.19Å; V88-D129 HydrophobicContact CG1-CB 3.94Å; V88-Y131 HydrophobicContact CG2-CD1 3.66Å; V88-Y131 HydrophobicContact CG2-CD2 3.99Å; V88-Y131 HydrophobicContact CG2-CE1 4.27Å; V88-Y131 HydrophobicContact CG2-CG 3.5Å; V88-Y131 VanDerWaalsContact CG2-CG 3.5Å
89	N	89.2	Confident	84.4	Confident	95 Å²	95	75.7 Å²	75.7	51%	0.508	38%	0.377	S	S	.	.			trans	-105.5	156	173.5	-66.9	-36.4	0	0	0	110.4	S91 Y92 V93	N89-S91 PolarHBondContact O-N 2.96Å; N89-S91 VanDerWaalsContact O-N 3.17Å; N89-Y92 WeakPolarHBondContact O-CA 3.37Å; N89-Y92 VanDerWaalsContact O-CB 3.28Å; N89-Y92 WeakPolarHBondContact O-CB 3.48Å; N89-Y92 PolarHBondContact O-N 2.93Å; N89-V93 PolarHBondContact O-N 3.26Å
90	N	91.1	Very high	86	Confident	142 Å²	142	66.9 Å²	66.9	76%	0.759	34%	0.343	S	S	*	.	H	α-helix	trans	-56.2	-36.8	178.5	-68.6	-12.8	0	0	0	112.9	V93 A94	N90-V93 PolarHBondContact O-N 2.86Å; N90-A94 PolarHBondContact O-N 3.42Å; N90-A94 VanDerWaalsContact O-N 3.09Å
91	S	89.6	Confident	87.6	Confident	72 Å²	72	60.2 Å²	60.2	50%	0.503	32%	0.315	S	S	.	.	H	α-helix	trans	-63.7	-40	174.8	-175.5	0	0	0	0	112.3	N89 K95	N89-S91 PolarHBondContact O-N 2.96Å; N89-S91 VanDerWaalsContact O-N 3.17Å; S91-K95 WeakPolarHBondContact O-CB 3.44Å; S91-K95 VanDerWaalsContact O-CG 3.27Å; S91-K95 WeakPolarHBondContact O-CG 3.32Å; S91-K95 PolarHBondContact O-N 3.16Å; S91-K95 VanDerWaalsContact O-N 3.15Å
92	Y	89.9	Confident	88.7	Confident	9 Å²	9	58.7 Å²	58.7	4%	0.035	31%	0.313	C	S	.	.	H	α-helix	trans	-61.6	-50.1	174.1	168.7	-93.1	0	0	0	110.8	V88 N89 A94 K95 K96 P121 D124 A127 D129 I132	V88-Y92 HydrophobicContact CB-CD1 3.81Å; V88-Y92 HydrophobicContact CB-CE1 4.31Å; V88-Y92 HydrophobicContact CG1-CD1 3.66Å; V88-Y92 HydrophobicContact CG1-CE1 3.64Å; N89-Y92 WeakPolarHBondContact O-CA 3.37Å; N89-Y92 VanDerWaalsContact O-CB 3.28Å; N89-Y92 WeakPolarHBondContact O-CB 3.48Å; N89-Y92 PolarHBondContact O-N 2.93Å; Y92-A94 VanDerWaalsContact C-N 3.35Å; Y92-A94 PolarHBondContact O-N 3.44Å; Y92-K95 PolarHBondContact O-N 3.49Å; Y92-K96 HydrophobicContact CD1-CB 4.46Å; Y92-K96 HydrophobicContact CE1-CB 4.1Å; Y92-K96 HydrophobicContact CE1-CG 4.17Å; Y92-K96 HydrophobicContact CE2-CD 4.33Å; Y92-K96 VanDerWaalsContact O-CB 3.25Å; Y92-K96 WeakPolarHBondContact O-CB 3.24Å; Y92-K96 PolarHBondContact O-N 3.07Å; Y92-K96 PolarHBondContact OH-NZ 2.88Å; Y92-P121 WeakPolarHBondContact CD2-O 3.31Å; Y92-P121 HydrophobicContact CE1-CB 4.09Å; Y92-P121 HydrophobicContact CE2-CB 3.82Å; Y92-P121 WeakPolarHBondContact CE2-O 3.48Å; Y92-D124 WeakPolarHBondContact CE2-O 3.1Å; Y92-A127 PolarHBondContact OH-O 3.44Å; Y92-D129 HydrophobicContact CE1-CB 4.02Å; Y92-D129 PolarHBondContact OH-OD1 3.49Å; Y92-D129 VanDerWaalsContact OH-OD1 3.07Å; Y92-I132 HydrophobicContact CE1-CD1 4.14Å
93	V	92.3	Very high	89.4	Confident	25 Å²	25	55.6 Å²	55.6	15%	0.152	30%	0.297	C	S	.	.	H	α-helix	trans	-57.5	-47.7	-177.5	174.7	0	0	0	0	111	V88 N89 N90 K95 K96 I97 Y131 I132	V88-V93 HydrophobicContact CB-CG2 4.3Å; V88-V93 HydrophobicContact CG2-CG2 4.18Å; N89-V93 PolarHBondContact O-N 3.26Å; N90-V93 PolarHBondContact O-N 2.86Å; V93-K95 PolarHBondContact O-N 3.01Å; V93-K96 PolarHBondContact O-N 3.38Å; V93-I97 HydrophobicContact CG1-CD1 3.75Å; V93-I97 HydrophobicContact CG1-CG1 4.43Å; V93-I97 WeakPolarHBondContact O-CB 3.26Å; V93-I97 VanDerWaalsContact O-CG1 3.3Å; V93-I97 WeakPolarHBondContact O-CG1 3.49Å; V93-I97 PolarHBondContact O-N 2.98Å; V93-Y131 HydrophobicContact CG2-CD1 3.93Å; V93-Y131 HydrophobicContact CG2-CE1 3.82Å; V93-I132 HydrophobicContact CG1-CD1 4.34Å; V93-I132 HydrophobicContact CG1-CG1 4.18Å; V93-I132 HydrophobicContact CG2-CG1 4.37Å
94	A	91.9	Very high	89.8	Confident	66 Å²	66	53.4 Å²	53.4	55%	0.545	29%	0.288	S	S	.	.	H	α-helix	trans	-60.8	-46.2	178.4	0	0	0	0	0	112.2	N90 Y92 G98	N90-A94 PolarHBondContact O-N 3.42Å; N90-A94 VanDerWaalsContact O-N 3.09Å; Y92-A94 VanDerWaalsContact C-N 3.35Å; Y92-A94 PolarHBondContact O-N 3.44Å; A94-G98 PolarHBondContact O-N 3.45Å
95	K	91.5	Very high	89.8	Confident	126 Å²	126	54.8 Å²	54.8	55%	0.548	31%	0.311	S	S	.	.	H	α-helix	trans	-64.6	-41	177.7	-70.9	175.6	-176.9	177.7	0	111.9	S91 Y92 V93 G98 L99 I125	S91-K95 WeakPolarHBondContact O-CB 3.44Å; S91-K95 VanDerWaalsContact O-CG 3.27Å; S91-K95 WeakPolarHBondContact O-CG 3.32Å; S91-K95 PolarHBondContact O-N 3.16Å; S91-K95 VanDerWaalsContact O-N 3.15Å; Y92-K95 PolarHBondContact O-N 3.49Å; V93-K95 PolarHBondContact O-N 3.01Å; K95-G98 PolarHBondContact O-N 3.19Å; K95-L99 WeakPolarHBondContact O-CB 3.42Å; K95-L99 PolarHBondContact O-N 3.5Å; K95-I125 HydrophobicContact CB-CD1 3.7Å; K95-I125 HydrophobicContact CB-CG1 4.39Å
96	K	92.7	Very high	89.8	Confident	0 Å²	0	56.3 Å²	56.3	0%	0	32%	0.318	C	S	.	.	H	α-helix	trans	-68.2	-41.8	-179.4	-171.4	74.1	173.5	-151.6	0	111.9	Y92 V93 G98 L99 I100 I125 A127 I132 Y201	Y92-K96 HydrophobicContact CD1-CB 4.46Å; Y92-K96 HydrophobicContact CE1-CB 4.1Å; Y92-K96 HydrophobicContact CE1-CG 4.17Å; Y92-K96 HydrophobicContact CE2-CD 4.33Å; Y92-K96 VanDerWaalsContact O-CB 3.25Å; Y92-K96 WeakPolarHBondContact O-CB 3.24Å; Y92-K96 PolarHBondContact O-N 3.07Å; Y92-K96 PolarHBondContact OH-NZ 2.88Å; V93-K96 PolarHBondContact O-N 3.38Å; K96-G98 VanDerWaalsContact C-N 3.34Å; K96-L99 HydrophobicContact CD-CD2 4.46Å; K96-L99 WeakPolarHBondContact O-CB 3.41Å; K96-L99 PolarHBondContact O-N 3Å; K96-I100 HydrophobicContact CG-CD1 4.23Å; K96-I100 VanDerWaalsContact O-CG1 3.29Å; K96-I100 WeakPolarHBondContact O-CG1 3.44Å; K96-I100 PolarHBondContact O-N 3.02Å; K96-I125 HydrophobicContact CD-CG1 4.37Å; K96-I125 VanDerWaalsContact CD-O 3.23Å; K96-I125 WeakPolarHBondContact CD-O 3.16Å; K96-I125 PolarHBondContact NZ-O 3.43Å; K96-A127 PolarHBondContact NZ-O 2.92Å; K96-I132 HydrophobicContact CB-CD1 3.53Å; K96-I132 HydrophobicContact CG-CD1 3.38Å; K96-Y201 VanDerWaalsContact CE-OH 3.29Å; K96-Y201 WeakPolarHBondContact CE-OH 3.32Å
97	I	93.4	Very high	89.1	Confident	61 Å²	61	58.4 Å²	58.4	31%	0.313	34%	0.338	S	S	.	.	H	α-helix	trans	-60.6	-46.4	171.8	-69.1	168.6	0	0	0	110	V93 L99 I100 L101 V204	V93-I97 HydrophobicContact CG1-CD1 3.75Å; V93-I97 HydrophobicContact CG1-CG1 4.43Å; V93-I97 WeakPolarHBondContact O-CB 3.26Å; V93-I97 VanDerWaalsContact O-CG1 3.3Å; V93-I97 WeakPolarHBondContact O-CG1 3.49Å; V93-I97 PolarHBondContact O-N 2.98Å; I97-L99 VanDerWaalsContact C-N 3.29Å; I97-L99 PolarHBondContact O-N 3.03Å; I97-I100 PolarHBondContact O-N 3.22Å; I97-L101 HydrophobicContact CG2-CD1 3.9Å; I97-L101 HydrophobicContact CG2-CG 4.41Å; I97-L101 WeakPolarHBondContact O-CG 3.32Å; I97-L101 PolarHBondContact O-N 3.32Å; I97-V204 HydrophobicContact CG2-CG1 4.21Å
98	G	93.1	Very high	88.7	Confident	31 Å²	31	63.9 Å²	63.9	32%	0.32	35%	0.354	S	S	.	.	H	α-helix	trans	-57.3	-41.3	174.5	0	0	0	0	0	112.7	A94 K95 K96 L101 F102	A94-G98 PolarHBondContact O-N 3.45Å; K95-G98 PolarHBondContact O-N 3.19Å; K96-G98 VanDerWaalsContact C-N 3.34Å; G98-L101 PolarHBondContact O-N 3.33Å; G98-F102 WeakPolarHBondContact O-CA 3.38Å; G98-F102 WeakPolarHBondContact O-CB 3.38Å; G98-F102 PolarHBondContact O-N 3.23Å
99	L	92.8	Very high	88.3	Confident	8 Å²	8	63.6 Å²	63.6	4%	0.042	35%	0.351	C	S	.	.	H	α-helix	trans	-64.1	-43.1	175.8	178.3	64	0	0	0	112.4	K95 K96 I97 F102 P103 H106 W109 I125 F235	K95-L99 WeakPolarHBondContact O-CB 3.42Å; K95-L99 PolarHBondContact O-N 3.5Å; K96-L99 HydrophobicContact CD-CD2 4.46Å; K96-L99 WeakPolarHBondContact O-CB 3.41Å; K96-L99 PolarHBondContact O-N 3Å; I97-L99 VanDerWaalsContact C-N 3.29Å; I97-L99 PolarHBondContact O-N 3.03Å; L99-F102 CarbonylContact O-C 3.51Å; L99-P103 WeakPolarHBondContact O-CA 3.35Å; L99-P103 VanDerWaalsContact O-CB 3.23Å; L99-P103 WeakPolarHBondContact O-CB 3.48Å; L99-P103 WeakPolarHBondContact O-CD 3.32Å; L99-P103 VanDerWaalsContact O-N 3.08Å; L99-H106 HydrophobicContact CD1-CB 3.25Å; L99-W109 HydrophobicContact CD1-CH2 4.12Å; L99-W109 HydrophobicContact CD1-CZ3 4.46Å; L99-I125 HydrophobicContact CB-CD1 4.23Å; L99-I125 HydrophobicContact CD2-CD1 4.12Å; L99-I125 HydrophobicContact CD2-CG1 3.98Å; L99-F235 HydrophobicContact CD2-CD2 4.43Å; L99-F235 HydrophobicContact CD2-CE2 3.86Å; L99-F235 HydrophobicContact CG-CD2 4.08Å; L99-F235 HydrophobicContact CG-CE2 3.94Å
100	I	93.2	Very high	87.1	Confident	0 Å²	0	61.2 Å²	61.2	0%	0	35%	0.349	C	S	.	.	H	α-helix	trans	-65.7	-40.1	179.3	-68	162.6	0	0	0	110.8	K96 I97 Y201 V204 L232 F235	K96-I100 HydrophobicContact CG-CD1 4.23Å; K96-I100 VanDerWaalsContact O-CG1 3.29Å; K96-I100 WeakPolarHBondContact O-CG1 3.44Å; K96-I100 PolarHBondContact O-N 3.02Å; I97-I100 PolarHBondContact O-N 3.22Å; I100-Y201 HydrophobicContact CD1-CD1 3.51Å; I100-Y201 HydrophobicContact CD1-CE1 4Å; I100-Y201 HydrophobicContact CD1-CG 4.01Å; I100-V204 HydrophobicContact CD1-CG2 4.35Å; I100-V204 HydrophobicContact CG2-CB 4.31Å; I100-V204 HydrophobicContact CG2-CG1 4.29Å; I100-L232 HydrophobicContact CG2-CD1 4.29Å; I100-F235 HydrophobicContact CG1-CD1 4.38Å; I100-F235 HydrophobicContact CG1-CD2 4.38Å; I100-F235 HydrophobicContact CG1-CE1 4.07Å; I100-F235 HydrophobicContact CG1-CE2 4.08Å; I100-F235 HydrophobicContact CG1-CZ 3.91Å
101	L	92.6	Very high	85.8	Confident	27 Å²	27	56.2 Å²	56.2	14%	0.141	32%	0.323	C	S	.	.	H	α-helix	trans	-80	-35.3	-178.8	-63.8	179.1	0	0	0	113.2	I97 G98 P103 V204 V208 Y227 T228	I97-L101 HydrophobicContact CG2-CD1 3.9Å; I97-L101 HydrophobicContact CG2-CG 4.41Å; I97-L101 WeakPolarHBondContact O-CG 3.32Å; I97-L101 PolarHBondContact O-N 3.32Å; G98-L101 PolarHBondContact O-N 3.33Å; L101-P103 WeakPolarHBondContact O-CD 3.28Å; L101-V204 HydrophobicContact CD2-CG1 4.32Å; L101-V208 HydrophobicContact CD1-CG2 3.85Å; L101-V208 HydrophobicContact CD2-CB 4.35Å; L101-V208 HydrophobicContact CD2-CG2 3.63Å; L101-V208 HydrophobicContact CG-CG2 4.4Å; L101-Y227 WeakPolarHBondContact O-CE1 3.33Å; L101-Y227 PolarHBondContact O-OH 2.94Å; L101-T228 HydrophobicContact CD2-CG2 4.47Å
102	F	93	Very high	84.4	Confident	120 Å²	120	57.7 Å²	57.7	53%	0.526	33%	0.325	S	S	.	.			trans	-124.6	58.5	-178.3	-57.1	-80.9	0	0	0	112.3	G98 L99 F104 A105 Y227	G98-F102 WeakPolarHBondContact O-CA 3.38Å; G98-F102 WeakPolarHBondContact O-CB 3.38Å; G98-F102 PolarHBondContact O-N 3.23Å; L99-F102 CarbonylContact O-C 3.51Å; F102-F104 PolarHBondContact O-N 2.84Å; F102-A105 PolarHBondContact O-N 3.35Å; F102-Y227 WeakPolarHBondContact CD1-OH 3.23Å; F102-Y227 HydrophobicContact CE1-CE1 4.46Å; F102-Y227 VanDerWaalsContact CE1-OH 3.31Å; F102-Y227 WeakPolarHBondContact CE1-OH 3.25Å
103	P	89.5	Confident	82.9	Confident	0 Å²	0	65.1 Å²	65.1	0%	0	35%	0.354	C	S	.	.	G	3₁₀ helix	trans	-72.3	-19.9	-173.7	29.9	-34.7	0	0	0	112.6	L99 L101 A105 H106 W109 A231 F234 F235	L99-P103 WeakPolarHBondContact O-CA 3.35Å; L99-P103 VanDerWaalsContact O-CB 3.23Å; L99-P103 WeakPolarHBondContact O-CB 3.48Å; L99-P103 WeakPolarHBondContact O-CD 3.32Å; L99-P103 VanDerWaalsContact O-N 3.08Å; L101-P103 WeakPolarHBondContact O-CD 3.28Å; P103-A105 PolarHBondContact O-N 2.97Å; P103-H106 PolarHBondContact O-N 3.4Å; P103-H106 VanDerWaalsContact O-N 3.14Å; P103-W109 HydrophobicContact CB-CH2 3.87Å; P103-W109 HydrophobicContact CB-CZ2 4.19Å; P103-W109 WeakPolarHBondContact O-CZ2 3.32Å; P103-A231 HydrophobicContact CG-CB 3.93Å; P103-A231 VanDerWaalsContact CG-O 3.27Å; P103-A231 WeakPolarHBondContact CG-O 3.45Å; P103-F234 HydrophobicContact CB-CD1 3.84Å; P103-F234 HydrophobicContact CB-CE1 4.36Å; P103-F234 HydrophobicContact CG-CD1 3.96Å; P103-F235 HydrophobicContact CB-CB 3.94Å; P103-F235 HydrophobicContact CG-CB 4.18Å
104	F	87.6	Confident	81.1	Confident	109 Å²	109	68.6 Å²	68.6	48%	0.478	37%	0.372	S	S	.	.	G	3₁₀ helix	trans	-64.1	-27	179.7	-47.8	-67	0	0	0	113.3	F102 H106 Y227 A231 F234	F102-F104 PolarHBondContact O-N 2.84Å; F104-H106 VanDerWaalsContact C-N 3.33Å; F104-Y227 HydrophobicContact CE2-CE2 4.35Å; F104-A231 HydrophobicContact CE2-CB 4.16Å; F104-A231 HydrophobicContact CZ-CB 4.34Å; F104-F234 AromaticContact CD1-CD1 3.94Å; F104-F234 HydrophobicContact CD1-CD1 3.94Å; F104-F234 HydrophobicContact CD1-CD2 4.34Å; F104-F234 HydrophobicContact CD1-CE1 4.15Å; F104-F234 HydrophobicContact CD1-CG 4.02Å; F104-F234 HydrophobicContact CD1-CZ 4.44Å; F104-F234 HydrophobicContact CE1-CB 3.83Å; F104-F234 HydrophobicContact CE1-CD1 4.08Å; F104-F234 HydrophobicContact CE1-CD2 4.18Å; F104-F234 AromaticContact CE1-CG 3.78Å; F104-F234 HydrophobicContact CE1-CG 3.78Å; F104-F234 HydrophobicContact CZ-CB 4.48Å
105	A	81.9	Confident	79.4	Confident	85 Å²	85	72 Å²	72	70%	0.702	39%	0.389	S	S	*	.	G	3₁₀ helix	trans	-82	-12.7	178.6	0	0	0	0	0	113	F102 P103	F102-A105 PolarHBondContact O-N 3.35Å; P103-A105 PolarHBondContact O-N 2.97Å
106	H	81.7	Confident	77.9	Confident	44 Å²	44	73.1 Å²	73.1	20%	0.204	41%	0.406	C	S	.	.			trans	-87.3	122.1	-176.5	-164.8	72.5	0	0	0	111.2	L99 P103 F104 K108 W109 N126	L99-H106 HydrophobicContact CD1-CB 3.25Å; P103-H106 PolarHBondContact O-N 3.4Å; P103-H106 VanDerWaalsContact O-N 3.14Å; F104-H106 VanDerWaalsContact C-N 3.33Å; H106-K108 PolarHBondContact NE2-O 3.32Å; H106-W109 HydrophobicContact CB-CZ2 4.01Å; H106-W109 AromaticContact CD2-CD2 3.76Å; H106-W109 AromaticContact CD2-CE2 3.76Å; H106-W109 AromaticContact CD2-NE1 3.97Å; H106-W109 PolarHBondContact O-NE1 3.42Å; H106-N126 PolarHBondContact NE2-OD1 3.32Å
107	T	73.2	Confident	76.3	Confident	125 Å²	125	74.5 Å²	74.5	77%	0.767	42%	0.419	S	S	*	.			trans	-102.6	-30.7	-178.3	50.1	0	0	0	0	112.8	W109	T107-W109 PolarHBondContact O-N 3.48Å
108	K	76.9	Confident	74.7	Confident	170 Å²	170	75.2 Å²	75.2	74%	0.739	43%	0.428	S	S	*	.			trans	-97.7	76.3	-173	-65.6	-174	179.3	-178.6	0	112.8	H106 G110 N126	H106-K108 PolarHBondContact NE2-O 3.32Å; K108-G110 PolarHBondContact O-N 2.83Å; K108-N126 PolarHBondContact O-ND2 3.01Å
109	W	76.9	Confident	73.2	Confident	21 Å²	21	74.1 Å²	74.1	8%	0.08	42%	0.415	C	S	.	.			trans	-80.2	-11	-177.8	-65.4	86.6	0	0	0	115.1	L99 P103 H106 T107 N126 F234 F235 R238 L242	L99-W109 HydrophobicContact CD1-CH2 4.12Å; L99-W109 HydrophobicContact CD1-CZ3 4.46Å; P103-W109 HydrophobicContact CB-CH2 3.87Å; P103-W109 HydrophobicContact CB-CZ2 4.19Å; P103-W109 WeakPolarHBondContact O-CZ2 3.32Å; H106-W109 HydrophobicContact CB-CZ2 4.01Å; H106-W109 AromaticContact CD2-CD2 3.76Å; H106-W109 AromaticContact CD2-CE2 3.76Å; H106-W109 AromaticContact CD2-NE1 3.97Å; H106-W109 PolarHBondContact O-NE1 3.42Å; T107-W109 PolarHBondContact O-N 3.48Å; W109-N126 VanDerWaalsContact C-ND2 3.25Å; W109-N126 VanDerWaalsContact O-CG 3.3Å; W109-N126 PolarHBondContact O-ND2 2.91Å; W109-F234 HydrophobicContact CZ2-CD1 4.44Å; W109-F234 AromaticContact CZ2-CE1 3.92Å; W109-F234 HydrophobicContact CZ2-CE1 3.92Å; W109-F235 AromaticContact CH2-CD2 3.97Å; W109-F235 HydrophobicContact CH2-CD2 3.97Å; W109-F235 AromaticContact CZ3-CD2 3.85Å; W109-F235 HydrophobicContact CZ3-CD2 3.85Å; W109-F235 HydrophobicContact CZ3-CE2 4.29Å; W109-R238 HydrophobicContact CD2-CB 3.58Å; W109-R238 HydrophobicContact CD2-CG 4.2Å; W109-R238 HydrophobicContact CE3-CB 3.48Å; W109-R238 VanDerWaalsContact CE3-CB 3.48Å; W109-R238 HydrophobicContact CG-CB 4.35Å; W109-R238 HydrophobicContact CH2-CB 3.69Å; W109-R238 HydrophobicContact CH2-CG 4.2Å; W109-R238 HydrophobicContact CZ2-CB 3.79Å; W109-R238 HydrophobicContact CZ2-CG 3.88Å; W109-R238 HydrophobicContact CZ3-CB 3.53Å; W109-R238 HydrophobicContact CZ3-CG 4.5Å; W109-L242 HydrophobicContact CB-CD1 3.42Å; W109-L242 VanDerWaalsContact CB-CD1 3.42Å; W109-L242 WeakPolarHBondContact O-CD1 3.45Å
110	G	64.3	Low	71.7	Confident	45 Å²	45	75.9 Å²	75.9	46%	0.464	43%	0.427	S	S	.	.	P	Polyproline II helix	trans	-61.7	142.1	-177.3	0	0	0	0	0	113	K108 N126	K108-G110 PolarHBondContact O-N 2.83Å; G110-N126 PolarHBondContact O-ND2 3.44Å
111	V	63.5	Low	70.1	Confident	37 Å²	37	75.9 Å²	75.9	22%	0.224	43%	0.427	C	S	.	.	P	Polyproline II helix	trans	-82.3	129.3	173.9	177.5	0	0	0	0	108.4	Y113 D124 N126	V111-Y113 HydrophobicContact CB-CE2 4.02Å; V111-Y113 HydrophobicContact CG1-CD2 4.45Å; V111-Y113 HydrophobicContact CG1-CE2 4.01Å; V111-Y113 WeakPolarHBondContact O-CD2 3.42Å; V111-D124 VanDerWaalsContact CA-OD2 3.25Å; V111-D124 WeakPolarHBondContact CA-OD2 3.29Å; V111-D124 WeakPolarHBondContact CG1-OD2 3.3Å; V111-N126 HydrophobicContact CG2-CB 4.3Å
112	N	60.1	Low	68.5	Low	102 Å²	102	75.4 Å²	75.4	55%	0.545	43%	0.429	S	S	.	.	P	Polyproline II helix	trans	-81.8	130	175.1	-64.4	-47	0	0	0	108.9	V119 D124	N112-V119 WeakPolarHBondContact O-CG2 3.31Å; N112-D124 PolarHBondContact N-OD2 2.82Å
113	Y	58	Low	67.1	Low	166 Å²	166	75.5 Å²	75.5	65%	0.651	44%	0.435	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-109.7	124.5	176	-70	-91.7	0	0	0	108.8	V111 P118	V111-Y113 HydrophobicContact CB-CE2 4.02Å; V111-Y113 HydrophobicContact CG1-CD2 4.45Å; V111-Y113 HydrophobicContact CG1-CE2 4.01Å; V111-Y113 WeakPolarHBondContact O-CD2 3.42Å; Y113-P118 HydrophobicContact CD1-CB 4.41Å; Y113-P118 HydrophobicContact CE1-CB 4.28Å
114	D	56.3	Low	66.4	Low	98 Å²	98	75.7 Å²	75.7	52%	0.524	44%	0.436	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-85.5	158.9	164.8	-86.7	-20.3	0	0	0	109.4	V116 G117 V119	D114-V116 PolarHBondContact O-N 3.33Å; D114-G117 PolarHBondContact N-O 3.23Å; D114-G117 PolarHBondContact O-N 3.02Å; D114-V119 HydrophobicContact CB-CG2 3.81Å
115	P	55.6	Low	66.1	Low	138 Å²	138	72.5 Å²	72.5	90%	0.896	42%	0.423	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.5	-20.7	-179.7	-22.9	32	0	0	0	114.1
116	V	59.7	Low	66.2	Low	149 Å²	149	68.9 Å²	68.9	90%	0.903	39%	0.392	S	S	*	.	T	Hydrogen-bonded Turn	trans	-89.6	-12.4	-176.7	-173.5	0	0	0	0	112.3	D114	D114-V116 PolarHBondContact O-N 3.33Å
117	G	58.6	Low	66.2	Low	28 Å²	28	66.9 Å²	66.9	29%	0.289	38%	0.383	S	S	.	.	E	Extended strand (participates in β ladder)	trans	137.9	-176.5	-177.6	0	0	0	0	0	112.9	D114 V119	D114-G117 PolarHBondContact N-O 3.23Å; D114-G117 PolarHBondContact O-N 3.02Å; G117-V119 PolarHBondContact O-N 3.42Å
118	P	60.2	Low	66.9	Low	76 Å²	76	61 Å²	61	49%	0.494	35%	0.348	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-60.6	129.1	178.1	26	-32.9	0	0	0	110.1	Y113	Y113-P118 HydrophobicContact CD1-CB 4.41Å; Y113-P118 HydrophobicContact CE1-CB 4.28Å
119	V	61.6	Low	67.6	Low	9 Å²	9	53 Å²	53	6%	0.055	31%	0.313	C	S	.	.	P	Polyproline II helix	trans	-64.2	140	-177.7	-174.8	0	0	0	0	109.4	Y84 N112 D114 G117 D123	Y84-V119 PolarHBondContact OH-O 2.93Å; N112-V119 WeakPolarHBondContact O-CG2 3.31Å; D114-V119 HydrophobicContact CB-CG2 3.81Å; G117-V119 PolarHBondContact O-N 3.42Å; V119-D123 HydrophobicContact CG1-CB 3.48Å; V119-D123 VanDerWaalsContact CG1-CB 3.48Å
120	P	61	Low	68.3	Low	44 Å²	44	52.9 Å²	52.9	29%	0.286	31%	0.314	S	S	.	.	P	Polyproline II helix	trans	-59.7	155.7	175.3	24.3	-34.2	0	0	0	112.2	Y84 G122 D123 D124	Y84-P120 HydrophobicContact CD2-CB 4.2Å; Y84-P120 VanDerWaalsContact CE2-CA 3.42Å; Y84-P120 HydrophobicContact CE2-CB 4.15Å; P120-G122 PolarHBondContact O-N 2.96Å; P120-D123 PolarHBondContact O-N 3.24Å; P120-D123 VanDerWaalsContact O-N 3.07Å; P120-D124 PolarHBondContact O-N 2.65Å
121	P	60.4	Low	69.7	Low	0 Å²	0	54.2 Å²	54.2	0%	0	31%	0.305	C	S	.	.	T	Hydrogen-bonded Turn	trans	-54.5	-33.6	-175.1	-25.5	34.3	0	0	0	113.9	Y84 V88 Y92 D123 D124 A127 P128 D129	Y84-P121 HydrophobicContact CE1-CG 4.34Å; Y84-P121 VanDerWaalsContact O-CD 3.24Å; Y84-P121 WeakPolarHBondContact O-CD 3.4Å; V88-P121 HydrophobicContact CG1-CB 4.19Å; Y92-P121 WeakPolarHBondContact CD2-O 3.31Å; Y92-P121 HydrophobicContact CE1-CB 4.09Å; Y92-P121 HydrophobicContact CE2-CB 3.82Å; Y92-P121 WeakPolarHBondContact CE2-O 3.48Å; P121-D123 PolarHBondContact O-N 3.41Å; P121-D124 CarbonylContact O-C 3.41Å; P121-D124 PolarHBondContact O-N 2.97Å; P121-D124 VanDerWaalsContact O-O 3.1Å; P121-A127 HydrophobicContact CB-CB 4.26Å; P121-A127 HydrophobicContact CG-CB 4.16Å; P121-P128 VanDerWaalsContact CG-O 3.31Å; P121-P128 WeakPolarHBondContact CG-O 3.41Å; P121-D129 HydrophobicContact CB-CB 4.3Å; P121-D129 HydrophobicContact CG-CB 4.37Å
122	G	57.9	Low	71.2	Confident	18 Å²	18	52.8 Å²	52.8	19%	0.186	30%	0.296	C	S	.	.	T	Hydrogen-bonded Turn	trans	-47	-33.6	176	0	0	0	0	0	115.5	S87 P120	S87-G122 PolarHBondContact O-N 3.11Å; P120-G122 PolarHBondContact O-N 2.96Å
123	D	63.3	Low	72.8	Confident	121 Å²	121	48.4 Å²	48.4	65%	0.647	27%	0.273	S	S	*	.	T	Hydrogen-bonded Turn	trans	-111.7	-12	-176.3	-55.7	-46	0	0	0	113.3	V119 P120 P121	V119-D123 HydrophobicContact CG1-CB 3.48Å; V119-D123 VanDerWaalsContact CG1-CB 3.48Å; P120-D123 PolarHBondContact O-N 3.24Å; P120-D123 VanDerWaalsContact O-N 3.07Å; P121-D123 PolarHBondContact O-N 3.41Å
124	D	75.7	Confident	74.6	Confident	4 Å²	4	43.8 Å²	43.8	2%	0.021	26%	0.26	C	S	.	.			trans	-125.6	109.7	172.2	-171.8	-0.9	0	0	0	112.5	Y92 V111 N112 P120 P121 N126 A127	Y92-D124 WeakPolarHBondContact CE2-O 3.1Å; V111-D124 VanDerWaalsContact CA-OD2 3.25Å; V111-D124 WeakPolarHBondContact CA-OD2 3.29Å; V111-D124 WeakPolarHBondContact CG1-OD2 3.3Å; N112-D124 PolarHBondContact N-OD2 2.82Å; P120-D124 PolarHBondContact O-N 2.65Å; P121-D124 CarbonylContact O-C 3.41Å; P121-D124 PolarHBondContact O-N 2.97Å; P121-D124 VanDerWaalsContact O-O 3.1Å; D124-N126 PolarHBondContact O-N 3.5Å; D124-N126 VanDerWaalsContact O-N 3.12Å; D124-N126 WeakPolarHBondContact OD1-CB 3.31Å; D124-N126 PolarHBondContact OD1-N 3.45Å; D124-A127 HydrophobicContact CB-CB 4.25Å; D124-A127 WeakPolarHBondContact O-CB 3.43Å; D124-A127 PolarHBondContact O-N 2.81Å; D124-A127 VanDerWaalsContact O-N 3.11Å
125	I	81.6	Confident	76.4	Confident	42 Å²	42	42.8 Å²	42.8	22%	0.215	25%	0.253	C	S	.	.	T	Hydrogen-bonded Turn	trans	-57.9	-26.1	176.7	-160.3	177.1	0	0	0	113.3	K95 K96 L99	K95-I125 HydrophobicContact CB-CD1 3.7Å; K95-I125 HydrophobicContact CB-CG1 4.39Å; K96-I125 HydrophobicContact CD-CG1 4.37Å; K96-I125 VanDerWaalsContact CD-O 3.23Å; K96-I125 WeakPolarHBondContact CD-O 3.16Å; K96-I125 PolarHBondContact NZ-O 3.43Å; L99-I125 HydrophobicContact CB-CD1 4.23Å; L99-I125 HydrophobicContact CD2-CD1 4.12Å; L99-I125 HydrophobicContact CD2-CG1 3.98Å
126	N	83.1	Confident	78.4	Confident	9 Å²	9	36.5 Å²	36.5	5%	0.048	21%	0.213	C	C	.	.	T	Hydrogen-bonded Turn	trans	-84.5	-16.5	-178	-65.9	-47.7	0	0	0	113.1	H106 K108 W109 G110 V111 D124	H106-N126 PolarHBondContact NE2-OD1 3.32Å; K108-N126 PolarHBondContact O-ND2 3.01Å; W109-N126 VanDerWaalsContact C-ND2 3.25Å; W109-N126 VanDerWaalsContact O-CG 3.3Å; W109-N126 PolarHBondContact O-ND2 2.91Å; G110-N126 PolarHBondContact O-ND2 3.44Å; V111-N126 HydrophobicContact CG2-CB 4.3Å; D124-N126 PolarHBondContact O-N 3.5Å; D124-N126 VanDerWaalsContact O-N 3.12Å; D124-N126 WeakPolarHBondContact OD1-CB 3.31Å; D124-N126 PolarHBondContact OD1-N 3.45Å
127	A	83.3	Confident	80.1	Confident	2 Å²	2	29.7 Å²	29.7	2%	0.017	17%	0.172	C	C	.	.	S	Bend	trans	-68.1	143.4	176.4	0	0	0	0	0	111.4	Y92 K96 P121 D124	Y92-A127 PolarHBondContact OH-O 3.44Å; K96-A127 PolarHBondContact NZ-O 2.92Å; P121-A127 HydrophobicContact CB-CB 4.26Å; P121-A127 HydrophobicContact CG-CB 4.16Å; D124-A127 HydrophobicContact CB-CB 4.25Å; D124-A127 WeakPolarHBondContact O-CB 3.43Å; D124-A127 PolarHBondContact O-N 2.81Å; D124-A127 VanDerWaalsContact O-N 3.11Å
128	P	87.2	Confident	81.9	Confident	3 Å²	3	32.1 Å²	32.1	2%	0.019	18%	0.177	C	C	.	.			trans	-73.7	147.7	178.2	34.5	-39	0	0	0	110.9	Y85 P121 D194 A197 Y198	Y85-P128 HydrophobicContact CD1-CG 4.35Å; Y85-P128 HydrophobicContact CE1-CB 4.27Å; Y85-P128 HydrophobicContact CE1-CG 3.79Å; P121-P128 VanDerWaalsContact CG-O 3.31Å; P121-P128 WeakPolarHBondContact CG-O 3.41Å; P128-D194 WeakPolarHBondContact CG-OD1 3.29Å; P128-A197 HydrophobicContact CB-CB 4.03Å; P128-Y198 HydrophobicContact CB-CE2 4.39Å
129	D	91.6	Very high	83.7	Confident	0 Å²	0	31.6 Å²	31.6	0%	0	17%	0.173	C	C	.	.			trans	-133.9	148.3	177.2	72.4	-83.2	0	0	0	109.5	V88 Y92 P121 I132 P133 A197 Y201	V88-D129 HydrophobicContact CG1-CB 3.94Å; Y92-D129 HydrophobicContact CE1-CB 4.02Å; Y92-D129 PolarHBondContact OH-OD1 3.49Å; Y92-D129 VanDerWaalsContact OH-OD1 3.07Å; P121-D129 HydrophobicContact CB-CB 4.3Å; P121-D129 HydrophobicContact CG-CB 4.37Å; D129-I132 WeakPolarHBondContact OD2-CA 3.36Å; D129-I132 WeakPolarHBondContact OD2-CB 3.38Å; D129-I132 WeakPolarHBondContact OD2-CG1 3.42Å; D129-I132 PolarHBondContact OD2-N 3.34Å; D129-P133 WeakPolarHBondContact O-CD 3.42Å; D129-A197 VanDerWaalsContact O-CB 3.24Å; D129-A197 WeakPolarHBondContact O-CB 3.45Å; D129-Y201 PolarHBondContact N-OH 3.48Å; D129-Y201 WeakPolarHBondContact OD1-CE1 3.22Å; D129-Y201 PolarHBondContact OD1-OH 3Å
130	L	91.3	Very high	85.3	Confident	20 Å²	20	31.2 Å²	31.2	11%	0.105	17%	0.17	C	C	.	.	S	Bend	trans	-98.9	-13.9	174.5	-74.4	168.6	0	0	0	111.8	Y85 F86 L134 L193 V196 A197	Y85-L130 HydrophobicContact CD1-CD1 4.26Å; Y85-L130 HydrophobicContact CD1-CG 4.1Å; Y85-L130 HydrophobicContact CD2-CD1 4.16Å; Y85-L130 HydrophobicContact CG-CD1 3.81Å; Y85-L130 HydrophobicContact CG-CG 4.02Å; Y85-L130 PolarHBondContact O-N 3.34Å; Y85-L130 VanDerWaalsContact O-N 3.1Å; F86-L130 HydrophobicContact CD2-CB 4.48Å; F86-L130 HydrophobicContact CE1-CB 4.42Å; F86-L130 HydrophobicContact CE2-CB 3.83Å; F86-L130 HydrophobicContact CE2-CD1 4.3Å; F86-L130 HydrophobicContact CZ-CB 3.79Å; L130-L134 VanDerWaalsContact O-CB 3.22Å; L130-L134 WeakPolarHBondContact O-CB 3.32Å; L130-L134 PolarHBondContact O-N 3.16Å; L130-L134 VanDerWaalsContact O-N 3.12Å; L130-L193 HydrophobicContact CD1-CB 4.18Å; L130-L193 HydrophobicContact CD1-CD2 4.01Å; L130-L193 HydrophobicContact CD1-CG 4.48Å; L130-V196 HydrophobicContact CD2-CB 4.11Å; L130-V196 HydrophobicContact CD2-CG1 3.77Å; L130-A197 HydrophobicContact CD2-CB 3.97Å; L130-A197 HydrophobicContact CG-CB 4.42Å
131	Y	93.5	Very high	87	Confident	73 Å²	73	30 Å²	30	29%	0.286	16%	0.161	S	C	.	.	H	α-helix	trans	-63.2	-51.1	179.3	177.6	-91.4	0	0	0	112	F86 V88 V93 L134 M135	F86-Y131 HydrophobicContact CD1-CD2 4.31Å; V88-Y131 HydrophobicContact CG2-CD1 3.66Å; V88-Y131 HydrophobicContact CG2-CD2 3.99Å; V88-Y131 HydrophobicContact CG2-CE1 4.27Å; V88-Y131 HydrophobicContact CG2-CG 3.5Å; V88-Y131 VanDerWaalsContact CG2-CG 3.5Å; V93-Y131 HydrophobicContact CG2-CD1 3.93Å; V93-Y131 HydrophobicContact CG2-CE1 3.82Å; Y131-L134 PolarHBondContact O-N 2.98Å; Y131-M135 HydrophobicContact CD1-CG 4.17Å; Y131-M135 HydrophobicContact CD2-CE 4.06Å; Y131-M135 HydrophobicContact CD2-CG 4.18Å; Y131-M135 HydrophobicContact CE1-CG 3.81Å; Y131-M135 HydrophobicContact CE2-CE 3.57Å; Y131-M135 HydrophobicContact CE2-CG 3.83Å; Y131-M135 HydrophobicContact CE2-SD 4.41Å; Y131-M135 HydrophobicContact CG-CG 4.34Å; Y131-M135 WeakPolarHBondContact O-CB 3.39Å; Y131-M135 VanDerWaalsContact O-CG 3.3Å; Y131-M135 WeakPolarHBondContact O-CG 3.44Å; Y131-M135 PolarHBondContact O-N 3Å
132	I	94.3	Very high	88.7	Confident	7 Å²	7	35 Å²	35	4%	0.036	19%	0.187	C	C	.	.	H	α-helix	trans	-64.8	-49.3	-177.5	-65.9	171.5	0	0	0	111.2	Y92 V93 K96 D129 L134 M135 A136 Y201 V204	Y92-I132 HydrophobicContact CE1-CD1 4.14Å; V93-I132 HydrophobicContact CG1-CD1 4.34Å; V93-I132 HydrophobicContact CG1-CG1 4.18Å; V93-I132 HydrophobicContact CG2-CG1 4.37Å; K96-I132 HydrophobicContact CB-CD1 3.53Å; K96-I132 HydrophobicContact CG-CD1 3.38Å; D129-I132 WeakPolarHBondContact OD2-CA 3.36Å; D129-I132 WeakPolarHBondContact OD2-CB 3.38Å; D129-I132 WeakPolarHBondContact OD2-CG1 3.42Å; D129-I132 PolarHBondContact OD2-N 3.34Å; I132-L134 VanDerWaalsContact C-N 3.3Å; I132-L134 PolarHBondContact O-N 3.35Å; I132-M135 PolarHBondContact O-N 3.41Å; I132-A136 WeakPolarHBondContact O-CB 3.26Å; I132-A136 PolarHBondContact O-N 2.97Å; I132-Y201 HydrophobicContact CB-CE1 4.27Å; I132-Y201 HydrophobicContact CG2-CD1 4.3Å; I132-Y201 HydrophobicContact CG2-CE1 4.38Å; I132-V204 HydrophobicContact CG2-CG2 3.53Å
133	P	95	Very high	90.5	Very high	10 Å²	10	35.5 Å²	35.5	7%	0.065	19%	0.185	C	C	.	.	H	α-helix	trans	-53.8	-44.4	173.7	-31.9	39	0	0	0	114.1	D129 S137 A197 Y201	D129-P133 WeakPolarHBondContact O-CD 3.42Å; P133-S137 WeakPolarHBondContact O-CB 3.29Å; P133-S137 PolarHBondContact O-N 3.29Å; P133-A197 WeakPolarHBondContact CG-O 3.44Å; P133-Y201 HydrophobicContact CG-CD1 3.8Å; P133-Y201 HydrophobicContact CG-CE1 3.86Å; P133-Y201 HydrophobicContact CG-CG 4.43Å
134	L	94.8	Very high	92	Very high	69 Å²	69	29.7 Å²	29.7	36%	0.361	16%	0.155	S	C	.	.	H	α-helix	trans	-65	-52	-179.9	-178.1	148	0	0	0	110.7	F86 L130 Y131 I132 A136 S137 I138	F86-L134 HydrophobicContact CE1-CD1 4.31Å; F86-L134 HydrophobicContact CZ-CD1 4.23Å; L130-L134 VanDerWaalsContact O-CB 3.22Å; L130-L134 WeakPolarHBondContact O-CB 3.32Å; L130-L134 PolarHBondContact O-N 3.16Å; L130-L134 VanDerWaalsContact O-N 3.12Å; Y131-L134 PolarHBondContact O-N 2.98Å; I132-L134 VanDerWaalsContact C-N 3.3Å; I132-L134 PolarHBondContact O-N 3.35Å; L134-A136 VanDerWaalsContact C-N 3.33Å; L134-A136 PolarHBondContact O-N 2.88Å; L134-S137 PolarHBondContact O-N 3.36Å; L134-S137 PolarHBondContact O-OG 2.99Å; L134-I138 HydrophobicContact CD2-CD1 3.74Å; L134-I138 HydrophobicContact CG-CD1 4.49Å; L134-I138 WeakPolarHBondContact O-CG1 3.32Å; L134-I138 PolarHBondContact O-N 3.36Å; L134-I138 VanDerWaalsContact O-N 3.16Å
135	M	95.7	Very high	92.9	Very high	76 Å²	76	29.9 Å²	29.9	37%	0.374	16%	0.157	S	C	.	.	H	α-helix	trans	-62.5	-42.3	180	-67.4	-57.9	160.6	0	0	111.3	Y131 I132 S137 I138 T139	Y131-M135 HydrophobicContact CD1-CG 4.17Å; Y131-M135 HydrophobicContact CD2-CE 4.06Å; Y131-M135 HydrophobicContact CD2-CG 4.18Å; Y131-M135 HydrophobicContact CE1-CG 3.81Å; Y131-M135 HydrophobicContact CE2-CE 3.57Å; Y131-M135 HydrophobicContact CE2-CG 3.83Å; Y131-M135 HydrophobicContact CE2-SD 4.41Å; Y131-M135 HydrophobicContact CG-CG 4.34Å; Y131-M135 WeakPolarHBondContact O-CB 3.39Å; Y131-M135 VanDerWaalsContact O-CG 3.3Å; Y131-M135 WeakPolarHBondContact O-CG 3.44Å; Y131-M135 PolarHBondContact O-N 3Å; I132-M135 PolarHBondContact O-N 3.41Å; M135-S137 VanDerWaalsContact C-N 3.34Å; M135-S137 PolarHBondContact O-N 2.82Å; M135-I138 PolarHBondContact O-N 3.48Å; M135-T139 WeakPolarHBondContact O-CB 3.4Å; M135-T139 PolarHBondContact O-N 2.68Å; M135-T139 PolarHBondContact O-OG1 2.65Å
136	A	97	Very high	93.5	Very high	7 Å²	7	31.3 Å²	31.3	6%	0.058	17%	0.168	C	C	.	.	H	α-helix	trans	-63.6	-37.4	176.5	0	0	0	0	0	112.3	I132 L134 T139 Y140 F203 V204 I207	I132-A136 WeakPolarHBondContact O-CB 3.26Å; I132-A136 PolarHBondContact O-N 2.97Å; L134-A136 VanDerWaalsContact C-N 3.33Å; L134-A136 PolarHBondContact O-N 2.88Å; A136-T139 PolarHBondContact O-N 3.24Å; A136-Y140 VanDerWaalsContact O-CB 3.24Å; A136-Y140 WeakPolarHBondContact O-CB 3.36Å; A136-Y140 PolarHBondContact O-N 2.81Å; A136-F203 HydrophobicContact CB-CB 3.6Å; A136-V204 HydrophobicContact CB-CG2 3.82Å; A136-I207 HydrophobicContact CB-CD1 3.86Å; A136-I207 WeakPolarHBondContact O-CD1 3.26Å
137	S	96.1	Very high	94	Very high	6 Å²	6	31 Å²	31	4%	0.042	17%	0.166	C	C	.	.	H	α-helix	trans	-63	-42.9	175.6	73	0	0	0	0	112	P133 L134 M135 Y140 I141	P133-S137 WeakPolarHBondContact O-CB 3.29Å; P133-S137 PolarHBondContact O-N 3.29Å; L134-S137 PolarHBondContact O-N 3.36Å; L134-S137 PolarHBondContact O-OG 2.99Å; M135-S137 VanDerWaalsContact C-N 3.34Å; M135-S137 PolarHBondContact O-N 2.82Å; S137-Y140 PolarHBondContact O-N 2.63Å; S137-I141 WeakPolarHBondContact O-CD1 3.37Å; S137-I141 VanDerWaalsContact O-CG1 3.31Å; S137-I141 WeakPolarHBondContact O-CG1 3.26Å; S137-I141 PolarHBondContact O-N 3.11Å; S137-I141 VanDerWaalsContact O-N 3.11Å
138	I	96.4	Very high	94.5	Very high	79 Å²	79	31.8 Å²	31.8	41%	0.405	17%	0.169	S	C	.	.	H	α-helix	trans	-64.9	-47.9	176.1	-63.3	170	0	0	0	110	L134 M135 Y140 I141 L142	L134-I138 HydrophobicContact CD2-CD1 3.74Å; L134-I138 HydrophobicContact CG-CD1 4.49Å; L134-I138 WeakPolarHBondContact O-CG1 3.32Å; L134-I138 PolarHBondContact O-N 3.36Å; L134-I138 VanDerWaalsContact O-N 3.16Å; M135-I138 PolarHBondContact O-N 3.48Å; I138-Y140 VanDerWaalsContact C-N 3.31Å; I138-Y140 PolarHBondContact O-N 3.47Å; I138-I141 PolarHBondContact O-N 3.21Å; I138-L142 HydrophobicContact CG2-CD1 4Å; I138-L142 HydrophobicContact CG2-CG 4.38Å; I138-L142 WeakPolarHBondContact O-CG 3.46Å; I138-L142 PolarHBondContact O-N 3.01Å
139	T	96.9	Very high	94.7	Very high	65 Å²	65	33.6 Å²	33.6	40%	0.399	19%	0.188	S	C	.	.	H	α-helix	trans	-61.5	-39	178.2	-56.4	0	0	0	0	111.9	M135 A136 L142 L143 I207	M135-T139 WeakPolarHBondContact O-CB 3.4Å; M135-T139 PolarHBondContact O-N 2.68Å; M135-T139 PolarHBondContact O-OG1 2.65Å; A136-T139 PolarHBondContact O-N 3.24Å; T139-L142 PolarHBondContact O-N 2.92Å; T139-L143 WeakPolarHBondContact O-CB 3.49Å; T139-L143 PolarHBondContact O-N 3.06Å; T139-I207 HydrophobicContact CG2-CD1 3.8Å; T139-I207 HydrophobicContact CG2-CG1 4.24Å; T139-I207 HydrophobicContact CG2-CG2 4.48Å
140	Y	96.3	Very high	94.7	Very high	0 Å²	0	41 Å²	41	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-60.1	-46.9	175.2	164.5	-104.9	0	0	0	111.8	A136 S137 I138 L143 S144 L162 A166 F203 M206 L210 L277 V281	A136-Y140 VanDerWaalsContact O-CB 3.24Å; A136-Y140 WeakPolarHBondContact O-CB 3.36Å; A136-Y140 PolarHBondContact O-N 2.81Å; S137-Y140 PolarHBondContact O-N 2.63Å; I138-Y140 VanDerWaalsContact C-N 3.31Å; I138-Y140 PolarHBondContact O-N 3.47Å; Y140-L143 PolarHBondContact O-N 2.95Å; Y140-S144 WeakPolarHBondContact O-CB 3.35Å; Y140-S144 PolarHBondContact O-N 3.47Å; Y140-S144 PolarHBondContact O-OG 3.45Å; Y140-L162 HydrophobicContact CE1-CD1 4.37Å; Y140-L162 HydrophobicContact CE1-CD2 4.15Å; Y140-L162 HydrophobicContact CE1-CG 4.1Å; Y140-L162 WeakPolarHBondContact OH-CD1 3.31Å; Y140-A166 HydrophobicContact CE1-CB 4.17Å; Y140-F203 HydrophobicContact CD1-CD1 4.13Å; Y140-F203 HydrophobicContact CD1-CE1 4.24Å; Y140-F203 HydrophobicContact CG-CD1 4.25Å; Y140-M206 HydrophobicContact CD2-CB 4Å; Y140-M206 HydrophobicContact CE2-CB 4.25Å; Y140-M206 HydrophobicContact CE2-SD 4.36Å; Y140-L210 HydrophobicContact CD2-CD1 3.71Å; Y140-L210 HydrophobicContact CE2-CD1 3.76Å; Y140-L277 PolarHBondContact OH-O 3.28Å; Y140-V281 HydrophobicContact CE2-CG2 4.49Å
141	I	95.8	Very high	94.6	Very high	20 Å²	20	42.8 Å²	42.8	10%	0.103	23%	0.228	C	C	.	.	H	α-helix	trans	-60	-52.5	177	-67.3	162.6	0	0	0	109.4	S137 I138 L143 S144 G145 L159 S163 F167	S137-I141 WeakPolarHBondContact O-CD1 3.37Å; S137-I141 VanDerWaalsContact O-CG1 3.31Å; S137-I141 WeakPolarHBondContact O-CG1 3.26Å; S137-I141 PolarHBondContact O-N 3.11Å; S137-I141 VanDerWaalsContact O-N 3.11Å; I138-I141 PolarHBondContact O-N 3.21Å; I141-L143 PolarHBondContact O-N 2.84Å; I141-S144 WeakPolarHBondContact O-CB 3.2Å; I141-S144 PolarHBondContact O-N 3.41Å; I141-G145 PolarHBondContact O-N 2.82Å; I141-L159 HydrophobicContact CG2-CD1 3.45Å; I141-L159 VanDerWaalsContact CG2-CD1 3.45Å; I141-L159 HydrophobicContact CG2-CD2 4.05Å; I141-L159 HydrophobicContact CG2-CG 3.5Å; I141-L159 VanDerWaalsContact CG2-CG 3.5Å; I141-L159 WeakPolarHBondContact O-CD1 3.44Å; I141-S163 WeakPolarHBondContact CD1-OG 3.18Å; I141-F167 HydrophobicContact CD1-CE2 4.02Å; I141-F167 HydrophobicContact CD1-CZ 4.48Å
142	L	95.7	Very high	94.4	Very high	105 Å²	105	42.7 Å²	42.7	55%	0.55	25%	0.25	S	C	.	.	H	α-helix	trans	-60	-45.1	-179.5	-67.9	177.2	0	0	0	112.7	I138 T139 S144 G145 V146	I138-L142 HydrophobicContact CG2-CD1 4Å; I138-L142 HydrophobicContact CG2-CG 4.38Å; I138-L142 WeakPolarHBondContact O-CG 3.46Å; I138-L142 PolarHBondContact O-N 3.01Å; T139-L142 PolarHBondContact O-N 2.92Å; L142-S144 VanDerWaalsContact C-N 3.32Å; L142-S144 PolarHBondContact O-N 3.19Å; L142-G145 WeakPolarHBondContact O-CA 3.11Å; L142-G145 PolarHBondContact O-N 3.42Å; L142-G145 VanDerWaalsContact O-N 3.12Å; L142-V146 PolarHBondContact O-N 2.87Å
143	L	95.8	Very high	94.2	Very high	27 Å²	27	49.2 Å²	49.2	14%	0.141	27%	0.274	C	S	.	.	H	α-helix	trans	-63.8	-38.4	178.9	-177.5	61.9	0	0	0	111.7	T139 Y140 I141 G145 V146 I147 I207 L210 I211 I214	T139-L143 WeakPolarHBondContact O-CB 3.49Å; T139-L143 PolarHBondContact O-N 3.06Å; Y140-L143 PolarHBondContact O-N 2.95Å; I141-L143 PolarHBondContact O-N 2.84Å; L143-G145 VanDerWaalsContact C-N 3.3Å; L143-G145 PolarHBondContact O-N 3.44Å; L143-V146 WeakPolarHBondContact O-CB 3.33Å; L143-V146 PolarHBondContact O-N 3.45Å; L143-I147 WeakPolarHBondContact O-CG1 3.43Å; L143-I147 PolarHBondContact O-N 2.91Å; L143-I207 HydrophobicContact CD2-CG2 4.03Å; L143-L210 HydrophobicContact CD2-CB 3.58Å; L143-L210 HydrophobicContact CD2-CD1 4.17Å; L143-L210 HydrophobicContact CG-CB 4.18Å; L143-L210 HydrophobicContact CG-CD1 4.32Å; L143-I211 HydrophobicContact CD2-CG1 3.83Å; L143-I214 HydrophobicContact CD1-CD1 3.85Å
144	S	94.4	Very high	93.9	Very high	0 Å²	0	54.3 Å²	54.3	0%	0	30%	0.295	C	S	.	.	H	α-helix	trans	-63.6	-38.8	173.6	-55.9	0	0	0	0	111.3	Y140 I141 L142 V146 I147 F148 L162 L210	Y140-S144 WeakPolarHBondContact O-CB 3.35Å; Y140-S144 PolarHBondContact O-N 3.47Å; Y140-S144 PolarHBondContact O-OG 3.45Å; I141-S144 WeakPolarHBondContact O-CB 3.2Å; I141-S144 PolarHBondContact O-N 3.41Å; L142-S144 VanDerWaalsContact C-N 3.32Å; L142-S144 PolarHBondContact O-N 3.19Å; S144-V146 VanDerWaalsContact C-N 3.34Å; S144-V146 PolarHBondContact O-N 3.14Å; S144-I147 PolarHBondContact O-N 3.42Å; S144-F148 VanDerWaalsContact O-CD2 3.25Å; S144-F148 WeakPolarHBondContact O-CD2 3.45Å; S144-F148 WeakPolarHBondContact O-CG 3.5Å; S144-F148 PolarHBondContact O-N 3Å; S144-L162 WeakPolarHBondContact OG-CD2 3.45Å; S144-L210 WeakPolarHBondContact OG-CD1 3.16Å
145	G	94.6	Very high	93.7	Very high	8 Å²	8	52.9 Å²	52.9	8%	0.082	29%	0.291	C	S	.	.	H	α-helix	trans	-58.6	-41.4	171.1	0	0	0	0	0	113.2	I141 L142 L143 F148 G149	I141-G145 PolarHBondContact O-N 2.82Å; L142-G145 WeakPolarHBondContact O-CA 3.11Å; L142-G145 PolarHBondContact O-N 3.42Å; L142-G145 VanDerWaalsContact O-N 3.12Å; L143-G145 VanDerWaalsContact C-N 3.3Å; L143-G145 PolarHBondContact O-N 3.44Å; G145-F148 PolarHBondContact O-N 2.84Å; G145-G149 PolarHBondContact O-N 3.34Å
146	V	94.2	Very high	93.5	Very high	71 Å²	71	53.7 Å²	53.7	43%	0.43	30%	0.302	S	S	.	.	H	α-helix	trans	-62.4	-44	174.6	175.1	0	0	0	0	111.2	L142 L143 S144 G149 F150	L142-V146 PolarHBondContact O-N 2.87Å; L143-V146 WeakPolarHBondContact O-CB 3.33Å; L143-V146 PolarHBondContact O-N 3.45Å; S144-V146 VanDerWaalsContact C-N 3.34Å; S144-V146 PolarHBondContact O-N 3.14Å; V146-G149 WeakPolarHBondContact O-CA 3.42Å; V146-G149 PolarHBondContact O-N 2.68Å; V146-G149 VanDerWaalsContact O-N 3.15Å; V146-F150 HydrophobicContact CG1-CD2 4.17Å; V146-F150 HydrophobicContact CG1-CE2 3.67Å; V146-F150 HydrophobicContact CG1-CZ 3.86Å; V146-F150 PolarHBondContact O-N 3.4Å
147	I	93.5	Very high	93.3	Very high	4 Å²	4	60.1 Å²	60.1	2%	0.021	33%	0.331	C	S	.	.	H	α-helix	trans	-62.3	-45.2	177.4	-67.2	169.3	0	0	0	111	L143 S144 G149 F150 Q151 L210 Y213 I214 V281	L143-I147 WeakPolarHBondContact O-CG1 3.43Å; L143-I147 PolarHBondContact O-N 2.91Å; S144-I147 PolarHBondContact O-N 3.42Å; I147-G149 VanDerWaalsContact C-N 3.25Å; I147-G149 PolarHBondContact O-N 3.46Å; I147-F150 PolarHBondContact O-N 2.9Å; I147-Q151 WeakPolarHBondContact O-CG 3.38Å; I147-Q151 PolarHBondContact O-N 3.28Å; I147-L210 HydrophobicContact CD1-CB 3.88Å; I147-L210 HydrophobicContact CD1-CD1 4.23Å; I147-L210 HydrophobicContact CD1-CD2 3.87Å; I147-L210 HydrophobicContact CD1-CG 4.2Å; I147-Y213 HydrophobicContact CD1-CD1 4.32Å; I147-Y213 HydrophobicContact CG2-CD1 4.49Å; I147-Y213 HydrophobicContact CG2-CE1 4.07Å; I147-I214 HydrophobicContact CD1-CD1 4.16Å; I147-I214 HydrophobicContact CD1-CG1 4.18Å; I147-I214 HydrophobicContact CG1-CD1 3.83Å; I147-I214 HydrophobicContact CG1-CG1 3.91Å; I147-V281 HydrophobicContact CB-CG1 4.21Å; I147-V281 HydrophobicContact CD1-CG1 4Å; I147-V281 HydrophobicContact CG2-CG1 4.11Å
148	F	93.5	Very high	93.1	Very high	18 Å²	18	66.1 Å²	66.1	8%	0.079	35%	0.353	C	S	.	.	H	α-helix	trans	-62.1	-34.4	174.5	-63.2	-37.3	0	0	0	112.6	S144 G145 Q151 G152 R153 F154 L162 V281	S144-F148 VanDerWaalsContact O-CD2 3.25Å; S144-F148 WeakPolarHBondContact O-CD2 3.45Å; S144-F148 WeakPolarHBondContact O-CG 3.5Å; S144-F148 PolarHBondContact O-N 3Å; G145-F148 PolarHBondContact O-N 2.84Å; F148-Q151 PolarHBondContact O-N 3.27Å; F148-G152 PolarHBondContact O-N 3.41Å; F148-R153 PolarHBondContact O-N 3.02Å; F148-F154 HydrophobicContact CB-CD2 4.46Å; F148-F154 PolarHBondContact O-N 3.22Å; F148-L162 HydrophobicContact CE2-CD2 4.44Å; F148-V281 HydrophobicContact CE1-CG1 4.31Å; F148-V281 HydrophobicContact CZ-CG1 4.38Å; F148-V281 HydrophobicContact CZ-CG2 4.46Å
149	G	92.9	Very high	92.9	Very high	40 Å²	40	64.4 Å²	64.4	41%	0.412	35%	0.345	S	S	.	.	H	α-helix	trans	-59.6	-49.9	171.4	0	0	0	0	0	112.3	G145 V146 I147 Q151 G152	G145-G149 PolarHBondContact O-N 3.34Å; V146-G149 WeakPolarHBondContact O-CA 3.42Å; V146-G149 PolarHBondContact O-N 2.68Å; V146-G149 VanDerWaalsContact O-N 3.15Å; I147-G149 VanDerWaalsContact C-N 3.25Å; I147-G149 PolarHBondContact O-N 3.46Å; G149-Q151 VanDerWaalsContact C-N 3.27Å; G149-Q151 PolarHBondContact O-N 3.16Å; G149-G152 PolarHBondContact O-N 3.27Å; G149-G152 VanDerWaalsContact O-N 3.1Å
150	F	91.2	Very high	92.7	Very high	157 Å²	157	63 Å²	63	69%	0.689	34%	0.344	S	S	*	.	H	α-helix	trans	-64	-30.4	176.7	-67.5	-28.2	0	0	0	113.5	V146 I147 G152	V146-F150 HydrophobicContact CG1-CD2 4.17Å; V146-F150 HydrophobicContact CG1-CE2 3.67Å; V146-F150 HydrophobicContact CG1-CZ 3.86Å; V146-F150 PolarHBondContact O-N 3.4Å; I147-F150 PolarHBondContact O-N 2.9Å; F150-G152 VanDerWaalsContact C-N 3.29Å; F150-G152 PolarHBondContact O-N 2.96Å
151	Q	89.6	Confident	92.6	Very high	56 Å²	56	67 Å²	67	26%	0.262	36%	0.364	S	S	.	.	T	Hydrogen-bonded Turn	trans	-81.7	-3.4	176.3	-67.3	176.6	-1.8	0	0	113.8	I147 F148 G149 R153	I147-Q151 WeakPolarHBondContact O-CG 3.38Å; I147-Q151 PolarHBondContact O-N 3.28Å; F148-Q151 PolarHBondContact O-N 3.27Å; G149-Q151 VanDerWaalsContact C-N 3.27Å; G149-Q151 PolarHBondContact O-N 3.16Å; Q151-R153 HydrophobicContact CB-CG 4.39Å; Q151-R153 PolarHBondContact O-N 2.78Å
152	G	90	Very high	92.5	Very high	71 Å²	71	66.3 Å²	66.3	73%	0.732	36%	0.361	S	S	*	.	T	Hydrogen-bonded Turn	trans	67.6	17.2	-176.3	0	0	0	0	0	114.2	F148 G149 F150	F148-G152 PolarHBondContact O-N 3.41Å; G149-G152 PolarHBondContact O-N 3.27Å; G149-G152 VanDerWaalsContact O-N 3.1Å; F150-G152 VanDerWaalsContact C-N 3.29Å; F150-G152 PolarHBondContact O-N 2.96Å
153	R	88.7	Confident	92.5	Very high	144 Å²	144	62.8 Å²	62.8	54%	0.543	35%	0.345	S	S	.	.			trans	-109.7	14.2	-178.1	-62.8	179.4	-177.1	174.7	0.4	112.5	F148 Q151 S155 Y158 L283	F148-R153 PolarHBondContact O-N 3.02Å; Q151-R153 HydrophobicContact CB-CG 4.39Å; Q151-R153 PolarHBondContact O-N 2.78Å; R153-S155 PolarHBondContact O-N 3.36Å; R153-S155 VanDerWaalsContact O-N 3.14Å; R153-Y158 WeakPolarHBondContact O-CD2 3.43Å; R153-L283 PolarHBondContact NH1-O 3.38Å
154	F	89.9	Confident	92.4	Very high	117 Å²	117	65.4 Å²	65.4	51%	0.513	37%	0.365	S	S	.	.			trans	-63.7	119.5	-176.3	-178.2	-98.2	0	0	0	111	F148	F148-F154 HydrophobicContact CB-CD2 4.46Å; F148-F154 PolarHBondContact O-N 3.22Å
155	S	90.6	Very high	92.4	Very high	39 Å²	39	67.7 Å²	67.7	27%	0.273	38%	0.376	S	S	.	.			trans	-137.4	135.3	164.7	174.7	0	0	0	0	107.7	R153 E157 Y158	R153-S155 PolarHBondContact O-N 3.36Å; R153-S155 VanDerWaalsContact O-N 3.14Å; S155-E157 PolarHBondContact O-N 2.68Å; S155-E157 VanDerWaalsContact O-N 3.11Å; S155-E157 PolarHBondContact OG-N 3.04Å; S155-Y158 PolarHBondContact O-N 3.34Å; S155-Y158 VanDerWaalsContact O-N 3.1Å
156	P	91	Very high	92.4	Very high	93 Å²	93	67.4 Å²	67.4	60%	0.604	37%	0.373	S	S	*	.	H	α-helix	trans	-58.7	-23.8	176.8	25.1	-34.6	0	0	0	112.5	L159 G160	P156-L159 WeakPolarHBondContact O-CB 3.5Å; P156-L159 PolarHBondContact O-N 2.9Å; P156-G160 PolarHBondContact O-N 2.81Å; P156-G160 VanDerWaalsContact O-N 3.1Å
157	E	92.9	Very high	92.5	Very high	143 Å²	143	68.1 Å²	68.1	67%	0.668	37%	0.37	S	S	*	.	H	α-helix	trans	-66.5	-37.7	177.3	-168.4	149.1	-177.5	0	0	112.5	S155 L159 G160 I161	S155-E157 PolarHBondContact O-N 2.68Å; S155-E157 VanDerWaalsContact O-N 3.11Å; S155-E157 PolarHBondContact OG-N 3.04Å; E157-L159 VanDerWaalsContact C-N 3.26Å; E157-L159 PolarHBondContact O-N 3.18Å; E157-G160 PolarHBondContact O-N 3.19Å; E157-I161 HydrophobicContact CG-CD1 4.18Å; E157-I161 WeakPolarHBondContact O-CG1 3.16Å; E157-I161 PolarHBondContact O-N 3.02Å
158	Y	91.1	Very high	92.6	Very high	132 Å²	132	69.8 Å²	69.8	52%	0.518	39%	0.388	S	S	.	.	H	α-helix	trans	-63.8	-34.8	173.5	-69	-57.1	0	0	0	112	R153 S155 L162	R153-Y158 WeakPolarHBondContact O-CD2 3.43Å; S155-Y158 PolarHBondContact O-N 3.34Å; S155-Y158 VanDerWaalsContact O-N 3.1Å; Y158-L162 WeakPolarHBondContact O-CB 3.41Å; Y158-L162 PolarHBondContact O-N 3.49Å
159	L	92.2	Very high	92.6	Very high	42 Å²	42	72.8 Å²	72.8	22%	0.22	40%	0.399	C	S	.	.	H	α-helix	trans	-67.4	-41.3	177.7	-158.6	71.4	0	0	0	111.4	I141 P156 E157 S163	I141-L159 HydrophobicContact CG2-CD1 3.45Å; I141-L159 VanDerWaalsContact CG2-CD1 3.45Å; I141-L159 HydrophobicContact CG2-CD2 4.05Å; I141-L159 HydrophobicContact CG2-CG 3.5Å; I141-L159 VanDerWaalsContact CG2-CG 3.5Å; I141-L159 WeakPolarHBondContact O-CD1 3.44Å; P156-L159 WeakPolarHBondContact O-CB 3.5Å; P156-L159 PolarHBondContact O-N 2.9Å; E157-L159 VanDerWaalsContact C-N 3.26Å; E157-L159 PolarHBondContact O-N 3.18Å; L159-S163 VanDerWaalsContact O-CB 3.26Å; L159-S163 WeakPolarHBondContact O-CB 3.28Å; L159-S163 PolarHBondContact O-N 3.43Å
160	G	93.7	Very high	92.7	Very high	37 Å²	37	72 Å²	72	38%	0.381	39%	0.385	S	S	.	.	H	α-helix	trans	-61.5	-50.1	174	0	0	0	0	0	112	P156 E157 L162 S163 S164	P156-G160 PolarHBondContact O-N 2.81Å; P156-G160 VanDerWaalsContact O-N 3.1Å; E157-G160 PolarHBondContact O-N 3.19Å; G160-L162 PolarHBondContact O-N 2.99Å; G160-S163 WeakPolarHBondContact O-CB 3.02Å; G160-S163 PolarHBondContact O-N 3.41Å; G160-S164 WeakPolarHBondContact O-CB 3.34Å; G160-S164 PolarHBondContact O-N 3.47Å; G160-S164 PolarHBondContact O-OG 3.1Å
161	I	93.8	Very high	92.9	Very high	82 Å²	82	69.6 Å²	69.6	42%	0.421	38%	0.379	S	S	.	.	H	α-helix	trans	-58.8	-48.7	177.1	-65.9	165.1	0	0	0	110.4	E157 S163 S164 E165	E157-I161 HydrophobicContact CG-CD1 4.18Å; E157-I161 WeakPolarHBondContact O-CG1 3.16Å; E157-I161 PolarHBondContact O-N 3.02Å; I161-S163 VanDerWaalsContact C-N 3.32Å; I161-S163 PolarHBondContact O-N 2.87Å; I161-S164 PolarHBondContact O-N 2.97Å; I161-E165 HydrophobicContact CG2-CG 4.37Å; I161-E165 WeakPolarHBondContact O-CB 3.47Å; I161-E165 VanDerWaalsContact O-CG 3.31Å; I161-E165 WeakPolarHBondContact O-CG 3.42Å; I161-E165 PolarHBondContact O-N 2.94Å
162	L	94	Very high	93.1	Very high	7 Å²	7	70.8 Å²	70.8	4%	0.037	39%	0.387	C	S	.	.	H	α-helix	trans	-59.5	-43.2	179.3	-173.7	71.6	0	0	0	112.1	Y140 S144 F148 Y158 G160 E165 A166 V281	Y140-L162 HydrophobicContact CE1-CD1 4.37Å; Y140-L162 HydrophobicContact CE1-CD2 4.15Å; Y140-L162 HydrophobicContact CE1-CG 4.1Å; Y140-L162 WeakPolarHBondContact OH-CD1 3.31Å; S144-L162 WeakPolarHBondContact OG-CD2 3.45Å; F148-L162 HydrophobicContact CE2-CD2 4.44Å; Y158-L162 WeakPolarHBondContact O-CB 3.41Å; Y158-L162 PolarHBondContact O-N 3.49Å; G160-L162 PolarHBondContact O-N 2.99Å; L162-E165 PolarHBondContact O-N 3.35Å; L162-A166 VanDerWaalsContact O-CB 3.29Å; L162-A166 WeakPolarHBondContact O-CB 3.35Å; L162-A166 PolarHBondContact O-N 3.1Å; L162-V281 HydrophobicContact CD1-CG2 3.99Å; L162-V281 HydrophobicContact CD2-CG2 4.14Å
163	S	94.7	Very high	93.3	Very high	30 Å²	30	67.6 Å²	67.6	21%	0.21	35%	0.353	C	S	.	.	H	α-helix	trans	-61.8	-51.7	176.1	179.4	0	0	0	0	111.2	I141 L159 G160 I161 E165 A166 F167	I141-S163 WeakPolarHBondContact CD1-OG 3.18Å; L159-S163 VanDerWaalsContact O-CB 3.26Å; L159-S163 WeakPolarHBondContact O-CB 3.28Å; L159-S163 PolarHBondContact O-N 3.43Å; G160-S163 WeakPolarHBondContact O-CB 3.02Å; G160-S163 PolarHBondContact O-N 3.41Å; I161-S163 VanDerWaalsContact C-N 3.32Å; I161-S163 PolarHBondContact O-N 2.87Å; S163-E165 VanDerWaalsContact C-N 3.27Å; S163-E165 PolarHBondContact O-N 3.24Å; S163-A166 PolarHBondContact O-N 3.29Å; S163-F167 WeakPolarHBondContact O-CD2 3.31Å; S163-F167 PolarHBondContact O-N 3.25Å; S163-F167 WeakPolarHBondContact OG-CE2 3.28Å
164	S	95.1	Very high	93.5	Very high	83 Å²	83	61.4 Å²	61.4	58%	0.58	33%	0.331	S	S	*	.	H	α-helix	trans	-59.6	-37.7	177.9	-65.7	0	0	0	0	112.3	G160 I161 G168	G160-S164 WeakPolarHBondContact O-CB 3.34Å; G160-S164 PolarHBondContact O-N 3.47Å; G160-S164 PolarHBondContact O-OG 3.1Å; I161-S164 PolarHBondContact O-N 2.97Å; S164-G168 WeakPolarHBondContact O-CA 3.27Å; S164-G168 PolarHBondContact O-N 3.48Å
165	E	94.2	Very high	93.7	Very high	47 Å²	47	60.7 Å²	60.7	22%	0.22	33%	0.332	C	S	.	.	H	α-helix	trans	-69.8	-45.6	175.4	-73.2	-169.3	150.1	0	0	112.6	I161 L162 S163 F167 G168 W169 R280	I161-E165 HydrophobicContact CG2-CG 4.37Å; I161-E165 WeakPolarHBondContact O-CB 3.47Å; I161-E165 VanDerWaalsContact O-CG 3.31Å; I161-E165 WeakPolarHBondContact O-CG 3.42Å; I161-E165 PolarHBondContact O-N 2.94Å; L162-E165 PolarHBondContact O-N 3.35Å; S163-E165 VanDerWaalsContact C-N 3.27Å; S163-E165 PolarHBondContact O-N 3.24Å; E165-F167 VanDerWaalsContact C-N 3.35Å; E165-F167 PolarHBondContact O-N 2.95Å; E165-G168 PolarHBondContact O-N 3.4Å; E165-W169 WeakPolarHBondContact O-CB 3.43Å; E165-W169 PolarHBondContact O-N 3.12Å; E165-R280 IonicContact OE1-CZ 3.22Å; E165-R280 VanDerWaalsContact OE1-CZ 3.22Å; E165-R280 IonicContact OE1-NH1 2.58Å; E165-R280 PolarHBondContact OE1-NH1 3.15Å; E165-R280 IonicContact OE1-NH2 3.43Å; E165-R280 PolarHBondContact OE1-NH2 3.41Å; E165-R280 WeakPolarHBondContact OE2-CD 3.38Å; E165-R280 IonicContact OE2-CZ 3.18Å; E165-R280 IonicContact OE2-NE 2.65Å; E165-R280 IonicContact OE2-NH1 2.68Å; E165-R280 PolarHBondContact OE2-NH1 3.35Å
166	A	94.6	Very high	93.8	Very high	2 Å²	2	62.4 Å²	62.4	2%	0.017	34%	0.338	C	S	.	.	H	α-helix	trans	-58.4	-47.3	177.5	0	0	0	0	0	111.5	Y140 L162 S163 L170 F203	Y140-A166 HydrophobicContact CE1-CB 4.17Å; L162-A166 VanDerWaalsContact O-CB 3.29Å; L162-A166 WeakPolarHBondContact O-CB 3.35Å; L162-A166 PolarHBondContact O-N 3.1Å; S163-A166 PolarHBondContact O-N 3.29Å; A166-L170 WeakPolarHBondContact O-CB 3.03Å; A166-L170 PolarHBondContact O-N 3.11Å; A166-F203 HydrophobicContact CB-CE1 3.97Å; A166-F203 HydrophobicContact CB-CZ 4.21Å
167	F	95.3	Very high	93.7	Very high	87 Å²	87	58.3 Å²	58.3	38%	0.382	31%	0.311	S	S	.	.	H	α-helix	trans	-72.2	-37.3	177.2	-71.1	-58.8	0	0	0	112.8	I141 S163 E165 L170 L171	I141-F167 HydrophobicContact CD1-CE2 4.02Å; I141-F167 HydrophobicContact CD1-CZ 4.48Å; S163-F167 WeakPolarHBondContact O-CD2 3.31Å; S163-F167 PolarHBondContact O-N 3.25Å; S163-F167 WeakPolarHBondContact OG-CE2 3.28Å; E165-F167 VanDerWaalsContact C-N 3.35Å; E165-F167 PolarHBondContact O-N 2.95Å; F167-L170 HydrophobicContact CD1-CD2 4.36Å; F167-L170 PolarHBondContact O-N 3.18Å; F167-L171 VanDerWaalsContact O-CB 3.32Å; F167-L171 WeakPolarHBondContact O-CB 3.31Å; F167-L171 PolarHBondContact O-N 3.14Å
168	G	95.6	Very high	93.5	Very high	38 Å²	38	53.5 Å²	53.5	39%	0.392	29%	0.29	S	S	.	.	H	α-helix	trans	-62.3	-44.2	176.6	0	0	0	0	0	112	S164 E165 L171 L172	S164-G168 WeakPolarHBondContact O-CA 3.27Å; S164-G168 PolarHBondContact O-N 3.48Å; E165-G168 PolarHBondContact O-N 3.4Å; G168-L171 PolarHBondContact O-N 3.29Å; G168-L172 WeakPolarHBondContact O-CB 3.44Å; G168-L172 PolarHBondContact O-N 3.29Å
169	W	94.3	Very high	93.5	Very high	81 Å²	81	53.3 Å²	53.3	31%	0.307	29%	0.292	S	S	.	.	H	α-helix	trans	-69.1	-37.8	174.7	-82.1	115.5	0	0	0	113.2	E165 L172 E173 M273 W276	E165-W169 WeakPolarHBondContact O-CB 3.43Å; E165-W169 PolarHBondContact O-N 3.12Å; W169-L172 HydrophobicContact CE3-CD1 4.19Å; W169-L172 HydrophobicContact CE3-CD2 4.25Å; W169-L172 HydrophobicContact CZ3-CD1 4.02Å; W169-L172 HydrophobicContact CZ3-CD2 4.17Å; W169-L172 PolarHBondContact O-N 2.93Å; W169-E173 WeakPolarHBondContact O-CB 3.48Å; W169-E173 PolarHBondContact O-N 3.46Å; W169-M273 HydrophobicContact CB-CE 3.48Å; W169-M273 VanDerWaalsContact CB-CE 3.48Å; W169-M273 HydrophobicContact CD2-CE 3.43Å; W169-M273 VanDerWaalsContact CD2-CE 3.43Å; W169-M273 HydrophobicContact CD2-SD 4.3Å; W169-M273 HydrophobicContact CE3-CE 3.48Å; W169-M273 VanDerWaalsContact CE3-CE 3.48Å; W169-M273 HydrophobicContact CE3-SD 3.85Å; W169-M273 HydrophobicContact CG-CE 3.44Å; W169-M273 VanDerWaalsContact CG-CE 3.44Å; W169-M273 HydrophobicContact CZ3-CE 4.33Å; W169-M273 HydrophobicContact CZ3-SD 4.17Å; W169-W276 AromaticContact NE1-CD1 3.91Å; W169-W276 AromaticContact NE1-NE1 3.67Å
170	L	94.7	Very high	93.2	Very high	23 Å²	23	52.4 Å²	52.4	12%	0.12	29%	0.291	C	S	.	.	H	α-helix	trans	-60.4	-46.6	171.9	178	67.5	0	0	0	111.1	A166 F167 E173 V174 C199 F203	A166-L170 WeakPolarHBondContact O-CB 3.03Å; A166-L170 PolarHBondContact O-N 3.11Å; F167-L170 HydrophobicContact CD1-CD2 4.36Å; F167-L170 PolarHBondContact O-N 3.18Å; L170-E173 PolarHBondContact O-N 3.4Å; L170-V174 WeakPolarHBondContact O-CG2 3.3Å; L170-V174 PolarHBondContact O-N 3.45Å; L170-C199 HydrophobicContact CD1-CB 3.73Å; L170-F203 HydrophobicContact CD2-CE2 4.2Å
171	L	94.8	Very high	92.8	Very high	107 Å²	107	52 Å²	52	56%	0.56	28%	0.279	S	S	*	.	H	α-helix	trans	-61.2	-47.6	178	180	65.3	0	0	0	111	F167 G168 E173 V174 L175	F167-L171 VanDerWaalsContact O-CB 3.32Å; F167-L171 WeakPolarHBondContact O-CB 3.31Å; F167-L171 PolarHBondContact O-N 3.14Å; G168-L171 PolarHBondContact O-N 3.29Å; L171-E173 VanDerWaalsContact C-N 3.3Å; L171-E173 PolarHBondContact O-N 2.94Å; L171-V174 PolarHBondContact O-N 2.89Å; L171-L175 HydrophobicContact CD1-CD1 4.45Å; L171-L175 HydrophobicContact CD1-CG 4.4Å; L171-L175 HydrophobicContact CG-CD1 4.18Å; L171-L175 HydrophobicContact CG-CG 4.5Å; L171-L175 VanDerWaalsContact O-CG 3.32Å; L171-L175 WeakPolarHBondContact O-CG 3.46Å; L171-L175 PolarHBondContact O-N 2.98Å
172	L	94.7	Very high	92.4	Very high	82 Å²	82	56.7 Å²	56.7	43%	0.429	29%	0.293	S	S	.	.	H	α-helix	trans	-57.6	-44.3	177.1	-175.5	155.8	0	0	0	111.3	G168 W169 L175 L176	G168-L172 WeakPolarHBondContact O-CB 3.44Å; G168-L172 PolarHBondContact O-N 3.29Å; W169-L172 HydrophobicContact CE3-CD1 4.19Å; W169-L172 HydrophobicContact CE3-CD2 4.25Å; W169-L172 HydrophobicContact CZ3-CD1 4.02Å; W169-L172 HydrophobicContact CZ3-CD2 4.17Å; W169-L172 PolarHBondContact O-N 2.93Å; L172-L175 PolarHBondContact O-N 2.9Å; L172-L176 WeakPolarHBondContact O-CB 3.29Å; L172-L176 PolarHBondContact O-N 2.94Å
173	E	93.6	Very high	92.1	Very high	4 Å²	4	61.4 Å²	61.4	2%	0.019	32%	0.317	C	S	.	.	H	α-helix	trans	-64.3	-42.3	179.3	-168.9	-172.5	157.3	0	0	112.4	W169 L170 L171 L176 S177 C199 K202 I269 Q270	W169-E173 WeakPolarHBondContact O-CB 3.48Å; W169-E173 PolarHBondContact O-N 3.46Å; L170-E173 PolarHBondContact O-N 3.4Å; L171-E173 VanDerWaalsContact C-N 3.3Å; L171-E173 PolarHBondContact O-N 2.94Å; E173-L176 PolarHBondContact O-N 2.83Å; E173-S177 WeakPolarHBondContact O-CB 3.43Å; E173-S177 PolarHBondContact O-N 2.94Å; E173-S177 PolarHBondContact O-OG 3.09Å; E173-C199 HydrophobicContact CG-CB 4.46Å; E173-C199 PolarHBondContact OE1-SG 2.98Å; E173-K202 IonicContact OE2-NZ 3.93Å; E173-K202 PolarHBondContact OE2-NZ 3.33Å; E173-I269 HydrophobicContact CG-CG2 4.41Å; E173-Q270 PolarHBondContact OE1-NE2 2.88Å
174	V	93	Very high	91.4	Very high	14 Å²	14	62.2 Å²	62.2	9%	0.085	32%	0.319	C	S	.	.	H	α-helix	trans	-62.1	-49.2	174.6	172.2	0	0	0	0	109.7	L170 L171 L176 S177 L178 I195 V196 C199	L170-V174 WeakPolarHBondContact O-CG2 3.3Å; L170-V174 PolarHBondContact O-N 3.45Å; L171-V174 PolarHBondContact O-N 2.89Å; V174-L176 PolarHBondContact O-N 2.89Å; V174-S177 WeakPolarHBondContact O-CB 3.46Å; V174-S177 PolarHBondContact O-N 3.46Å; V174-S177 VanDerWaalsContact O-N 3.14Å; V174-L178 HydrophobicContact CG1-CD1 4.2Å; V174-L178 HydrophobicContact CG1-CG 4.32Å; V174-L178 VanDerWaalsContact O-CG 3.29Å; V174-L178 WeakPolarHBondContact O-CG 3.22Å; V174-L178 PolarHBondContact O-N 2.95Å; V174-I195 HydrophobicContact CG1-CG2 4.42Å; V174-V196 HydrophobicContact CG1-CG2 3.99Å; V174-V196 HydrophobicContact CG2-CB 4.49Å; V174-V196 HydrophobicContact CG2-CG2 3.97Å; V174-C199 HydrophobicContact CG2-CB 4.23Å
175	L	93.3	Very high	90.7	Very high	102 Å²	102	63 Å²	63	53%	0.534	32%	0.317	S	S	.	.	H	α-helix	trans	-60.3	-43.5	178.5	-69.9	178.2	0	0	0	112.4	L171 L172 S177 L178 F179	L171-L175 HydrophobicContact CD1-CD1 4.45Å; L171-L175 HydrophobicContact CD1-CG 4.4Å; L171-L175 HydrophobicContact CG-CD1 4.18Å; L171-L175 HydrophobicContact CG-CG 4.5Å; L171-L175 VanDerWaalsContact O-CG 3.32Å; L171-L175 WeakPolarHBondContact O-CG 3.46Å; L171-L175 PolarHBondContact O-N 2.98Å; L172-L175 PolarHBondContact O-N 2.9Å; L175-S177 VanDerWaalsContact C-N 3.3Å; L175-S177 PolarHBondContact O-N 3.2Å; L175-L178 PolarHBondContact O-N 3.35Å; L175-F179 VanDerWaalsContact O-CB 3.26Å; L175-F179 WeakPolarHBondContact O-CB 3.41Å; L175-F179 PolarHBondContact O-N 3.25Å
176	L	92.5	Very high	89.6	Confident	74 Å²	74	61.6 Å²	61.6	39%	0.387	31%	0.31	S	S	.	.	H	α-helix	trans	-61.9	-40.5	176.1	-171.7	76.3	0	0	0	111.1	L172 E173 V174 F179 A180 I269	L172-L176 WeakPolarHBondContact O-CB 3.29Å; L172-L176 PolarHBondContact O-N 2.94Å; E173-L176 PolarHBondContact O-N 2.83Å; V174-L176 PolarHBondContact O-N 2.89Å; L176-F179 PolarHBondContact O-N 3.19Å; L176-A180 VanDerWaalsContact O-CB 3.26Å; L176-A180 WeakPolarHBondContact O-CB 3.33Å; L176-A180 PolarHBondContact O-N 3.35Å; L176-I269 HydrophobicContact CD2-CD1 4.15Å
177	S	89.4	Confident	88.2	Confident	7 Å²	7	67.5 Å²	67.5	5%	0.049	34%	0.338	C	S	.	.	H	α-helix	trans	-66.8	-42.6	177.6	-60.3	0	0	0	0	111.8	E173 V174 L175 A180 M181	E173-S177 WeakPolarHBondContact O-CB 3.43Å; E173-S177 PolarHBondContact O-N 2.94Å; E173-S177 PolarHBondContact O-OG 3.09Å; V174-S177 WeakPolarHBondContact O-CB 3.46Å; V174-S177 PolarHBondContact O-N 3.46Å; V174-S177 VanDerWaalsContact O-N 3.14Å; L175-S177 VanDerWaalsContact C-N 3.3Å; L175-S177 PolarHBondContact O-N 3.2Å; S177-A180 PolarHBondContact O-N 3.35Å; S177-M181 WeakPolarHBondContact O-CG 3.46Å; S177-M181 PolarHBondContact O-N 3.45Å
178	L	89.2	Confident	86.5	Confident	43 Å²	43	65 Å²	65	23%	0.225	33%	0.328	C	S	.	.	H	α-helix	trans	-62.5	-45.6	174	-65	-176.2	0	0	0	111.5	V174 L175 M181 Y182 Y192 I195	V174-L178 HydrophobicContact CG1-CD1 4.2Å; V174-L178 HydrophobicContact CG1-CG 4.32Å; V174-L178 VanDerWaalsContact O-CG 3.29Å; V174-L178 WeakPolarHBondContact O-CG 3.22Å; V174-L178 PolarHBondContact O-N 2.95Å; L175-L178 PolarHBondContact O-N 3.35Å; L178-M181 HydrophobicContact CD2-CE 3.48Å; L178-M181 VanDerWaalsContact CD2-CE 3.48Å; L178-M181 PolarHBondContact O-N 3.49Å; L178-Y182 WeakPolarHBondContact O-CB 3.19Å; L178-Y182 PolarHBondContact O-N 3.38Å; L178-Y192 HydrophobicContact CD1-CD1 3.93Å; L178-Y192 HydrophobicContact CD1-CE1 4.37Å; L178-Y192 HydrophobicContact CD2-CD1 3.5Å; L178-Y192 HydrophobicContact CD2-CE1 3.94Å; L178-Y192 HydrophobicContact CG-CD1 4.37Å; L178-I195 HydrophobicContact CD2-CD1 3.58Å
179	F	90.1	Very high	85	Confident	127 Å²	127	71.4 Å²	71.4	56%	0.557	35%	0.353	S	S	*	.	H	α-helix	trans	-62.4	-43.8	177.1	-177.1	-104.8	0	0	0	111.7	L175 L176 M181 Y182 I183	L175-F179 VanDerWaalsContact O-CB 3.26Å; L175-F179 WeakPolarHBondContact O-CB 3.41Å; L175-F179 PolarHBondContact O-N 3.25Å; L176-F179 PolarHBondContact O-N 3.19Å; F179-M181 PolarHBondContact O-N 3.42Å; F179-Y182 WeakPolarHBondContact O-CB 3.49Å; F179-Y182 PolarHBondContact O-N 3.12Å; F179-I183 HydrophobicContact CD1-CG1 4.19Å; F179-I183 HydrophobicContact CD2-CG1 4.4Å; F179-I183 HydrophobicContact CE1-CD1 4.39Å; F179-I183 HydrophobicContact CE1-CG1 3.76Å; F179-I183 HydrophobicContact CE2-CD1 4.07Å; F179-I183 HydrophobicContact CE2-CG1 3.99Å; F179-I183 HydrophobicContact CG-CG1 4.5Å; F179-I183 HydrophobicContact CZ-CD1 3.81Å; F179-I183 HydrophobicContact CZ-CG1 3.65Å; F179-I183 WeakPolarHBondContact O-CG1 3.32Å; F179-I183 PolarHBondContact O-N 3.11Å
180	A	87.7	Confident	83.9	Confident	23 Å²	23	68.7 Å²	68.7	19%	0.19	35%	0.345	C	S	.	.	H	α-helix	trans	-61.5	-42.9	177	0	0	0	0	0	111.9	L176 S177 Y182 L184 L262	L176-A180 VanDerWaalsContact O-CB 3.26Å; L176-A180 WeakPolarHBondContact O-CB 3.33Å; L176-A180 PolarHBondContact O-N 3.35Å; S177-A180 PolarHBondContact O-N 3.35Å; A180-Y182 VanDerWaalsContact C-N 3.35Å; A180-L184 VanDerWaalsContact O-CB 3.26Å; A180-L184 WeakPolarHBondContact O-CB 3.44Å; A180-L184 WeakPolarHBondContact O-CG 3.3Å; A180-L184 PolarHBondContact O-N 2.91Å; A180-L262 HydrophobicContact CB-CD1 3.75Å
181	M	84.5	Confident	83.1	Confident	28 Å²	28	68.8 Å²	68.8	14%	0.138	35%	0.347	C	S	.	.	H	α-helix	trans	-64.4	-38.9	174.6	-71.7	-171.3	-56.4	0	0	112.7	S177 L178 F179 N185 I186 N188 I195 L262	S177-M181 WeakPolarHBondContact O-CG 3.46Å; S177-M181 PolarHBondContact O-N 3.45Å; L178-M181 HydrophobicContact CD2-CE 3.48Å; L178-M181 VanDerWaalsContact CD2-CE 3.48Å; L178-M181 PolarHBondContact O-N 3.49Å; F179-M181 PolarHBondContact O-N 3.42Å; M181-N185 PolarHBondContact O-N 2.92Å; M181-N185 VanDerWaalsContact O-N 3.1Å; M181-I186 PolarHBondContact O-N 3.25Å; M181-I186 VanDerWaalsContact O-N 3.11Å; M181-N188 PolarHBondContact SD-ND2 2.89Å; M181-I195 HydrophobicContact CE-CD1 3.12Å; M181-I195 HydrophobicContact SD-CD1 3.85Å; M181-L262 HydrophobicContact CB-CD1 4.41Å; M181-L262 HydrophobicContact CG-CD1 3.63Å
182	Y	85.3	Confident	82.6	Confident	182 Å²	182	71.8 Å²	71.8	71%	0.714	35%	0.352	S	S	*	.	H	α-helix	trans	-62	-51.5	176.9	177.7	-99.1	0	0	0	111.2	L178 F179 A180 L184 N185	L178-Y182 WeakPolarHBondContact O-CB 3.19Å; L178-Y182 PolarHBondContact O-N 3.38Å; F179-Y182 WeakPolarHBondContact O-CB 3.49Å; F179-Y182 PolarHBondContact O-N 3.12Å; A180-Y182 VanDerWaalsContact C-N 3.35Å; Y182-L184 PolarHBondContact O-N 3.1Å; Y182-N185 PolarHBondContact O-N 3.34Å; Y182-N185 VanDerWaalsContact O-N 3.09Å
183	I	86.8	Confident	82.2	Confident	105 Å²	105	70.1 Å²	70.1	54%	0.538	34%	0.343	S	S	.	.	H	α-helix	trans	-63.2	-40.8	178.9	-66.4	-64.4	0	0	0	111.8	F179 N185	F179-I183 HydrophobicContact CD1-CG1 4.19Å; F179-I183 HydrophobicContact CD2-CG1 4.4Å; F179-I183 HydrophobicContact CE1-CD1 4.39Å; F179-I183 HydrophobicContact CE1-CG1 3.76Å; F179-I183 HydrophobicContact CE2-CD1 4.07Å; F179-I183 HydrophobicContact CE2-CG1 3.99Å; F179-I183 HydrophobicContact CG-CG1 4.5Å; F179-I183 HydrophobicContact CZ-CD1 3.81Å; F179-I183 HydrophobicContact CZ-CG1 3.65Å; F179-I183 WeakPolarHBondContact O-CG1 3.32Å; F179-I183 PolarHBondContact O-N 3.11Å; I183-N185 PolarHBondContact O-N 3.31Å
184	L	81.8	Confident	82	Confident	48 Å²	48	70.6 Å²	70.6	25%	0.251	35%	0.346	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75.8	-4.1	178.7	-66.2	174.7	0	0	0	113.1	A180 Y182 I186 R258 L262	A180-L184 VanDerWaalsContact O-CB 3.26Å; A180-L184 WeakPolarHBondContact O-CB 3.44Å; A180-L184 WeakPolarHBondContact O-CG 3.3Å; A180-L184 PolarHBondContact O-N 2.91Å; Y182-L184 PolarHBondContact O-N 3.1Å; L184-I186 HydrophobicContact CB-CD1 3.81Å; L184-I186 HydrophobicContact CB-CG1 3.64Å; L184-I186 HydrophobicContact CD1-CD1 4.04Å; L184-I186 PolarHBondContact O-N 3.27Å; L184-R258 HydrophobicContact CD2-CB 4.41Å; L184-R258 HydrophobicContact CD2-CG 4.49Å; L184-L262 HydrophobicContact CD1-CB 3.87Å; L184-L262 HydrophobicContact CD1-CD1 3.92Å
185	N	78.8	Confident	81.8	Confident	100 Å²	100	70.5 Å²	70.5	54%	0.535	35%	0.345	S	S	.	.	T	Hydrogen-bonded Turn	trans	48.1	49	-177	-161.9	-34.1	0	0	0	111.3	M181 Y182 I183 Q187	M181-N185 PolarHBondContact O-N 2.92Å; M181-N185 VanDerWaalsContact O-N 3.1Å; Y182-N185 PolarHBondContact O-N 3.34Å; Y182-N185 VanDerWaalsContact O-N 3.09Å; I183-N185 PolarHBondContact O-N 3.31Å; N185-Q187 PolarHBondContact O-N 3.4Å
186	I	71.8	Confident	81.7	Confident	16 Å²	16	67.9 Å²	67.9	8%	0.082	33%	0.333	C	S	.	.			trans	-86.8	103.3	178.3	-51.3	174.2	0	0	0	107.2	M181 L184 N188 R259 L262	M181-I186 PolarHBondContact O-N 3.25Å; M181-I186 VanDerWaalsContact O-N 3.11Å; L184-I186 HydrophobicContact CB-CD1 3.81Å; L184-I186 HydrophobicContact CB-CG1 3.64Å; L184-I186 HydrophobicContact CD1-CD1 4.04Å; L184-I186 PolarHBondContact O-N 3.27Å; I186-N188 VanDerWaalsContact C-N 3.31Å; I186-N188 VanDerWaalsContact CG2-ND2 3.25Å; I186-N188 WeakPolarHBondContact CG2-ND2 3.43Å; I186-N188 WeakPolarHBondContact CG2-OD1 3.46Å; I186-N188 PolarHBondContact O-N 3.17Å; I186-R259 HydrophobicContact CD1-CG 4.01Å; I186-R259 HydrophobicContact CG1-CG 4.31Å; I186-R259 HydrophobicContact CG2-CG 3.81Å; I186-L262 HydrophobicContact CD1-CB 4.48Å; I186-L262 HydrophobicContact CD1-CD1 3.98Å
187	Q	65.1	Low	81.7	Confident	127 Å²	127	64.4 Å²	64.4	59%	0.593	32%	0.315	S	S	*	.			trans	-66.1	94.3	167.4	-65.4	-180	-0.8	0	0	108.2	N185	N185-Q187 PolarHBondContact O-N 3.4Å
188	N	60	Low	81.9	Confident	35 Å²	35	64.2 Å²	64.2	19%	0.187	31%	0.313	C	S	.	.			trans	-107.8	133.9	-179.7	-80	-32.8	0	0	0	109.4	M181 I186 I190	M181-N188 PolarHBondContact SD-ND2 2.89Å; I186-N188 VanDerWaalsContact C-N 3.31Å; I186-N188 VanDerWaalsContact CG2-ND2 3.25Å; I186-N188 WeakPolarHBondContact CG2-ND2 3.43Å; I186-N188 WeakPolarHBondContact CG2-OD1 3.46Å; I186-N188 PolarHBondContact O-N 3.17Å; N188-I190 HydrophobicContact CB-CB 4.06Å; N188-I190 HydrophobicContact CB-CD1 4.31Å; N188-I190 HydrophobicContact CB-CG1 4.05Å; N188-I190 PolarHBondContact O-N 3.44Å
189	N	63.7	Low	82	Confident	172 Å²	172	62.3 Å²	62.3	92%	0.92	30%	0.303	S	S	*	.			trans	-75.3	11.3	163.8	-69.4	-38.8	0	0	0	112.3	S191	N189-S191 PolarHBondContact O-N 2.81Å
190	I	71.5	Confident	82.3	Confident	24 Å²	24	56.3 Å²	56.3	12%	0.123	28%	0.277	C	S	.	.			trans	-80.5	119.2	-176.2	-60.3	177.4	0	0	0	108.1	N188 D194 I195 K243 I244	N188-I190 HydrophobicContact CB-CB 4.06Å; N188-I190 HydrophobicContact CB-CD1 4.31Å; N188-I190 HydrophobicContact CB-CG1 4.05Å; N188-I190 PolarHBondContact O-N 3.44Å; I190-D194 HydrophobicContact CG2-CB 3.57Å; I190-I195 HydrophobicContact CG2-CD1 4.37Å; I190-I195 HydrophobicContact CG2-CG1 3.99Å; I190-K243 HydrophobicContact CD1-CB 4.09Å; I190-K243 HydrophobicContact CG1-CB 4.33Å; I190-I244 HydrophobicContact CD1-CD1 4.4Å; I190-I244 HydrophobicContact CD1-CG1 3.45Å; I190-I244 VanDerWaalsContact CD1-CG1 3.45Å
191	S	78.3	Confident	82.6	Confident	24 Å²	24	55.2 Å²	55.2	17%	0.168	27%	0.268	C	S	.	.			trans	-63.6	144.4	174.2	-178.5	0	0	0	0	110.2	Y85 N189 L193 D194	Y85-S191 VanDerWaalsContact OH-CB 3.27Å; Y85-S191 WeakPolarHBondContact OH-CB 3.39Å; Y85-S191 PolarHBondContact OH-OG 3.47Å; N189-S191 PolarHBondContact O-N 2.81Å; S191-L193 PolarHBondContact O-N 3.09Å; S191-L193 VanDerWaalsContact O-N 3.08Å; S191-L193 PolarHBondContact OG-N 3.32Å; S191-D194 VanDerWaalsContact O-CB 3.31Å; S191-D194 WeakPolarHBondContact O-CB 2.98Å; S191-D194 PolarHBondContact O-N 3.42Å
192	Y	84.1	Confident	83.1	Confident	171 Å²	171	53.9 Å²	53.9	67%	0.671	26%	0.261	S	S	*	.	H	α-helix	trans	-51.2	-34.4	172.3	-57.6	-79.4	0	0	0	112	L178 D194 I195 V196	L178-Y192 HydrophobicContact CD1-CD1 3.93Å; L178-Y192 HydrophobicContact CD1-CE1 4.37Å; L178-Y192 HydrophobicContact CD2-CD1 3.5Å; L178-Y192 HydrophobicContact CD2-CE1 3.94Å; L178-Y192 HydrophobicContact CG-CD1 4.37Å; Y192-D194 VanDerWaalsContact C-N 3.33Å; Y192-D194 PolarHBondContact O-N 3.42Å; Y192-I195 PolarHBondContact O-N 3.47Å; Y192-V196 WeakPolarHBondContact O-CG2 3.31Å; Y192-V196 PolarHBondContact O-N 3.24Å
193	L	86.5	Confident	83.6	Confident	47 Å²	47	45.2 Å²	45.2	25%	0.246	23%	0.228	C	C	.	.	H	α-helix	trans	-66.6	-30.3	177.7	-63.6	178.7	0	0	0	113.3	I82 Y85 L130 S191 I195 V196 A197	I82-L193 HydrophobicContact CG1-CD1 4.25Å; Y85-L193 HydrophobicContact CD2-CB 4.08Å; Y85-L193 HydrophobicContact CD2-CD1 3.73Å; Y85-L193 HydrophobicContact CE1-CB 4.03Å; Y85-L193 HydrophobicContact CE2-CB 3.51Å; Y85-L193 HydrophobicContact CE2-CD1 3.42Å; Y85-L193 VanDerWaalsContact CE2-CD1 3.42Å; Y85-L193 HydrophobicContact CE2-CG 4.1Å; Y85-L193 VanDerWaalsContact CZ-CB 3.46Å; L130-L193 HydrophobicContact CD1-CB 4.18Å; L130-L193 HydrophobicContact CD1-CD2 4.01Å; L130-L193 HydrophobicContact CD1-CG 4.48Å; S191-L193 PolarHBondContact O-N 3.09Å; S191-L193 VanDerWaalsContact O-N 3.08Å; S191-L193 PolarHBondContact OG-N 3.32Å; L193-I195 VanDerWaalsContact C-N 3.32Å; L193-V196 PolarHBondContact O-N 3.47Å; L193-A197 WeakPolarHBondContact O-CB 3.42Å; L193-A197 PolarHBondContact O-N 3.28Å
194	D	88.2	Confident	84.1	Confident	13 Å²	13	40.8 Å²	40.8	7%	0.07	21%	0.205	C	C	.	.	H	α-helix	trans	-64.7	-40.8	174.8	-70.5	-0.9	0	0	0	110.7	Y85 P128 I190 S191 Y192 A197 Y198 K243	Y85-D194 WeakPolarHBondContact CE1-OD1 3.32Å; Y85-D194 VanDerWaalsContact CZ-OD1 3.25Å; Y85-D194 PolarHBondContact OH-OD1 3.35Å; P128-D194 WeakPolarHBondContact CG-OD1 3.29Å; I190-D194 HydrophobicContact CG2-CB 3.57Å; S191-D194 VanDerWaalsContact O-CB 3.31Å; S191-D194 WeakPolarHBondContact O-CB 2.98Å; S191-D194 PolarHBondContact O-N 3.42Å; Y192-D194 VanDerWaalsContact C-N 3.33Å; Y192-D194 PolarHBondContact O-N 3.42Å; D194-A197 WeakPolarHBondContact O-CB 3.41Å; D194-A197 PolarHBondContact O-N 3.04Å; D194-Y198 HydrophobicContact CB-CD2 4.4Å; D194-Y198 HydrophobicContact CB-CE2 4.24Å; D194-Y198 WeakPolarHBondContact O-CD2 3.38Å; D194-Y198 PolarHBondContact O-N 3.42Å; D194-K243 VanDerWaalsContact CG-NZ 3.29Å; D194-K243 IonicContact OD1-NZ 3.51Å; D194-K243 IonicContact OD2-NZ 3.68Å; D194-K243 PolarHBondContact OD2-NZ 2.72Å
195	I	89.2	Confident	84.8	Confident	13 Å²	13	38.5 Å²	38.5	7%	0.067	19%	0.193	C	C	.	.	H	α-helix	trans	-66.8	-44.3	-178.5	-63.9	166.5	0	0	0	109.8	V174 L178 M181 I190 Y192 L193 A197 Y198 C199	V174-I195 HydrophobicContact CG1-CG2 4.42Å; L178-I195 HydrophobicContact CD2-CD1 3.58Å; M181-I195 HydrophobicContact CE-CD1 3.12Å; M181-I195 HydrophobicContact SD-CD1 3.85Å; I190-I195 HydrophobicContact CG2-CD1 4.37Å; I190-I195 HydrophobicContact CG2-CG1 3.99Å; Y192-I195 PolarHBondContact O-N 3.47Å; L193-I195 VanDerWaalsContact C-N 3.32Å; I195-A197 VanDerWaalsContact C-N 3.29Å; I195-A197 PolarHBondContact O-N 3.23Å; I195-Y198 PolarHBondContact O-N 3.02Å; I195-C199 WeakPolarHBondContact O-CB 3.43Å; I195-C199 PolarHBondContact O-N 3.17Å; I195-C199 PolarHBondContact O-SG 3.39Å; I195-C199 VanDerWaalsContact O-SG 3.36Å
196	V	92.4	Very high	85.6	Confident	47 Å²	47	33.7 Å²	33.7	29%	0.285	17%	0.168	S	C	.	.	H	α-helix	trans	-57.5	-44.3	173.7	178.3	0	0	0	0	110.7	L130 V174 Y192 L193 G200	L130-V196 HydrophobicContact CD2-CB 4.11Å; L130-V196 HydrophobicContact CD2-CG1 3.77Å; V174-V196 HydrophobicContact CG1-CG2 3.99Å; V174-V196 HydrophobicContact CG2-CB 4.49Å; V174-V196 HydrophobicContact CG2-CG2 3.97Å; Y192-V196 WeakPolarHBondContact O-CG2 3.31Å; Y192-V196 PolarHBondContact O-N 3.24Å; L193-V196 PolarHBondContact O-N 3.47Å; V196-G200 PolarHBondContact O-N 2.97Å
197	A	92.5	Very high	86.8	Confident	0 Å²	0	34 Å²	34	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-60.1	-49.8	176.7	0	0	0	0	0	112	P128 D129 L130 P133 L193 D194 I195 G200 Y201	P128-A197 HydrophobicContact CB-CB 4.03Å; D129-A197 VanDerWaalsContact O-CB 3.24Å; D129-A197 WeakPolarHBondContact O-CB 3.45Å; L130-A197 HydrophobicContact CD2-CB 3.97Å; L130-A197 HydrophobicContact CG-CB 4.42Å; P133-A197 WeakPolarHBondContact CG-O 3.44Å; L193-A197 WeakPolarHBondContact O-CB 3.42Å; L193-A197 PolarHBondContact O-N 3.28Å; D194-A197 WeakPolarHBondContact O-CB 3.41Å; D194-A197 PolarHBondContact O-N 3.04Å; I195-A197 VanDerWaalsContact C-N 3.29Å; I195-A197 PolarHBondContact O-N 3.23Å; A197-G200 PolarHBondContact O-N 3.22Å; A197-Y201 VanDerWaalsContact O-CD2 3.29Å; A197-Y201 WeakPolarHBondContact O-CD2 3.42Å; A197-Y201 PolarHBondContact O-N 3.46Å; A197-Y201 VanDerWaalsContact O-N 3.17Å
198	Y	91.8	Very high	88.3	Confident	4 Å²	4	30 Å²	30	2%	0.016	15%	0.153	C	C	.	.	H	α-helix	trans	-64.8	-44.3	-178.9	-73.2	-60.9	0	0	0	113.3	P128 D194 I195 G200 Y201 L236 L240 K243	P128-Y198 HydrophobicContact CB-CE2 4.39Å; D194-Y198 HydrophobicContact CB-CD2 4.4Å; D194-Y198 HydrophobicContact CB-CE2 4.24Å; D194-Y198 WeakPolarHBondContact O-CD2 3.38Å; D194-Y198 PolarHBondContact O-N 3.42Å; I195-Y198 PolarHBondContact O-N 3.02Å; Y198-G200 PolarHBondContact O-N 3.05Å; Y198-Y201 HydrophobicContact CD1-CD2 4Å; Y198-Y201 AromaticContact CD1-CE2 3.84Å; Y198-Y201 HydrophobicContact CD1-CE2 3.84Å; Y198-Y201 HydrophobicContact CE1-CE2 4.17Å; Y198-Y201 PolarHBondContact O-N 3.4Å; Y198-L236 HydrophobicContact CD1-CD2 3.9Å; Y198-L236 HydrophobicContact CG-CD2 4.32Å; Y198-L240 HydrophobicContact CD1-CD2 4.47Å; Y198-L240 HydrophobicContact CD1-CG 4.49Å; Y198-L240 HydrophobicContact CD2-CD2 3.42Å; Y198-L240 VanDerWaalsContact CD2-CD2 3.42Å; Y198-L240 HydrophobicContact CD2-CG 4.26Å; Y198-L240 HydrophobicContact CE2-CD2 3.68Å; Y198-L240 HydrophobicContact CG-CD2 3.88Å; Y198-L240 HydrophobicContact CG-CG 4.27Å; Y198-K243 HydrophobicContact CE2-CD 3.98Å; Y198-K243 WeakPolarHBondContact OH-CD 3.23Å; Y198-K243 WeakPolarHBondContact OH-CE 3.16Å
199	C	93	Very high	90	Very high	2 Å²	2	28.3 Å²	28.3	1%	0.014	14%	0.144	C	C	.	.	H	α-helix	trans	-63.9	-29	175.2	-68.8	0	0	0	0	112.3	L170 E173 V174 I195 K202	L170-C199 HydrophobicContact CD1-CB 3.73Å; E173-C199 HydrophobicContact CG-CB 4.46Å; E173-C199 PolarHBondContact OE1-SG 2.98Å; V174-C199 HydrophobicContact CG2-CB 4.23Å; I195-C199 WeakPolarHBondContact O-CB 3.43Å; I195-C199 PolarHBondContact O-N 3.17Å; I195-C199 PolarHBondContact O-SG 3.39Å; I195-C199 VanDerWaalsContact O-SG 3.36Å; C199-K202 VanDerWaalsContact O-CD 3.32Å; C199-K202 WeakPolarHBondContact O-CD 3.28Å; C199-K202 WeakPolarHBondContact O-CE 3.46Å; C199-K202 WeakPolarHBondContact O-CG 3.33Å
200	G	94.4	Very high	91.5	Very high	1 Å²	1	20.1 Å²	20.1	1%	0.01	10%	0.101	C	C	.	.	H	α-helix	trans	-83.1	-19.3	-178	0	0	0	0	0	115	V196 A197 Y198 K202 F203	V196-G200 PolarHBondContact O-N 2.97Å; A197-G200 PolarHBondContact O-N 3.22Å; Y198-G200 PolarHBondContact O-N 3.05Å; G200-K202 PolarHBondContact O-N 2.87Å; G200-F203 WeakPolarHBondContact O-CD2 3.47Å; G200-F203 PolarHBondContact O-N 3.49Å
201	Y	95	Very high	92.7	Very high	0 Å²	0	23.5 Å²	23.5	0%	0	12%	0.118	C	C	.	.	T	Hydrogen-bonded Turn	trans	-61.4	-18.4	178.5	-71.8	-51.7	0	0	0	114	K96 I100 D129 I132 P133 A197 Y198 F203 V204 F235	K96-Y201 VanDerWaalsContact CE-OH 3.29Å; K96-Y201 WeakPolarHBondContact CE-OH 3.32Å; I100-Y201 HydrophobicContact CD1-CD1 3.51Å; I100-Y201 HydrophobicContact CD1-CE1 4Å; I100-Y201 HydrophobicContact CD1-CG 4.01Å; D129-Y201 PolarHBondContact N-OH 3.48Å; D129-Y201 WeakPolarHBondContact OD1-CE1 3.22Å; D129-Y201 PolarHBondContact OD1-OH 3Å; I132-Y201 HydrophobicContact CB-CE1 4.27Å; I132-Y201 HydrophobicContact CG2-CD1 4.3Å; I132-Y201 HydrophobicContact CG2-CE1 4.38Å; P133-Y201 HydrophobicContact CG-CD1 3.8Å; P133-Y201 HydrophobicContact CG-CE1 3.86Å; P133-Y201 HydrophobicContact CG-CG 4.43Å; A197-Y201 VanDerWaalsContact O-CD2 3.29Å; A197-Y201 WeakPolarHBondContact O-CD2 3.42Å; A197-Y201 PolarHBondContact O-N 3.46Å; A197-Y201 VanDerWaalsContact O-N 3.17Å; Y198-Y201 HydrophobicContact CD1-CD2 4Å; Y198-Y201 AromaticContact CD1-CE2 3.84Å; Y198-Y201 HydrophobicContact CD1-CE2 3.84Å; Y198-Y201 HydrophobicContact CE1-CE2 4.17Å; Y198-Y201 PolarHBondContact O-N 3.4Å; Y201-F203 PolarHBondContact O-N 3.19Å; Y201-V204 WeakPolarHBondContact O-CB 3.06Å; Y201-V204 PolarHBondContact O-N 2.85Å; Y201-V204 VanDerWaalsContact O-N 3.11Å; Y201-F235 AromaticContact CD2-CE1 3.64Å; Y201-F235 HydrophobicContact CD2-CE1 3.64Å; Y201-F235 HydrophobicContact CD2-CZ 4.19Å; Y201-F235 HydrophobicContact CE2-CE1 4.07Å; Y201-F235 HydrophobicContact CE2-CZ 4.19Å; Y201-F235 HydrophobicContact CG-CE1 4.21Å
202	K	95.3	Very high	93.5	Very high	0 Å²	0	23.9 Å²	23.9	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-57.2	-28.9	175.1	72.8	-171.3	174.3	-171.6	0	114	E173 C199 G200 V204 S205 M206 L232 M274	E173-K202 IonicContact OE2-NZ 3.93Å; E173-K202 PolarHBondContact OE2-NZ 3.33Å; C199-K202 VanDerWaalsContact O-CD 3.32Å; C199-K202 WeakPolarHBondContact O-CD 3.28Å; C199-K202 WeakPolarHBondContact O-CE 3.46Å; C199-K202 WeakPolarHBondContact O-CG 3.33Å; G200-K202 PolarHBondContact O-N 2.87Å; K202-V204 PolarHBondContact O-N 3.48Å; K202-S205 WeakPolarHBondContact O-CB 3.3Å; K202-S205 PolarHBondContact O-N 2.91Å; K202-S205 VanDerWaalsContact O-N 3.14Å; K202-M206 HydrophobicContact CB-CE 4.29Å; K202-M206 HydrophobicContact CD-CE 3.81Å; K202-M206 HydrophobicContact CG-CE 3.74Å; K202-M206 WeakPolarHBondContact O-CG 3.38Å; K202-M206 PolarHBondContact O-N 3.25Å; K202-L232 HydrophobicContact CB-CD2 3.63Å; K202-M274 HydrophobicContact CB-CG 4.35Å
203	F	96.4	Very high	94	Very high	1 Å²	1	17.4 Å²	17.4	0%	0.004	10%	0.095	C	C	.	.	H	α-helix	trans	-62.2	-31.4	178.7	-68.2	-63.7	0	0	0	112.1	A136 Y140 A166 L170 G200 Y201 M206 I207	A136-F203 HydrophobicContact CB-CB 3.6Å; Y140-F203 HydrophobicContact CD1-CD1 4.13Å; Y140-F203 HydrophobicContact CD1-CE1 4.24Å; Y140-F203 HydrophobicContact CG-CD1 4.25Å; A166-F203 HydrophobicContact CB-CE1 3.97Å; A166-F203 HydrophobicContact CB-CZ 4.21Å; L170-F203 HydrophobicContact CD2-CE2 4.2Å; G200-F203 WeakPolarHBondContact O-CD2 3.47Å; G200-F203 PolarHBondContact O-N 3.49Å; Y201-F203 PolarHBondContact O-N 3.19Å; F203-M206 HydrophobicContact CD1-SD 3.81Å; F203-M206 HydrophobicContact CE1-SD 4.19Å; F203-M206 PolarHBondContact O-N 2.81Å; F203-I207 WeakPolarHBondContact O-CD1 3.36Å; F203-I207 VanDerWaalsContact O-CG1 3.28Å; F203-I207 WeakPolarHBondContact O-CG1 3.29Å; F203-I207 PolarHBondContact O-N 2.99Å
204	V	96.9	Very high	94.3	Very high	11 Å²	11	18.9 Å²	18.9	7%	0.067	10%	0.102	C	C	.	.	H	α-helix	trans	-62.7	-47.1	174.8	-178.4	0	0	0	0	110.4	I97 I100 L101 I132 A136 Y201 K202 I207 V208	I97-V204 HydrophobicContact CG2-CG1 4.21Å; I100-V204 HydrophobicContact CD1-CG2 4.35Å; I100-V204 HydrophobicContact CG2-CB 4.31Å; I100-V204 HydrophobicContact CG2-CG1 4.29Å; L101-V204 HydrophobicContact CD2-CG1 4.32Å; I132-V204 HydrophobicContact CG2-CG2 3.53Å; A136-V204 HydrophobicContact CB-CG2 3.82Å; Y201-V204 WeakPolarHBondContact O-CB 3.06Å; Y201-V204 PolarHBondContact O-N 2.85Å; Y201-V204 VanDerWaalsContact O-N 3.11Å; K202-V204 PolarHBondContact O-N 3.48Å; V204-I207 PolarHBondContact O-N 3.24Å; V204-V208 PolarHBondContact O-N 3.2Å
205	S	96.4	Very high	94.6	Very high	0 Å²	0	21.2 Å²	21.2	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-61.5	-43.8	175.6	-66.3	0	0	0	0	111.8	K202 I207 V208 V209	K202-S205 WeakPolarHBondContact O-CB 3.3Å; K202-S205 PolarHBondContact O-N 2.91Å; K202-S205 VanDerWaalsContact O-N 3.14Å; S205-I207 VanDerWaalsContact C-N 3.34Å; S205-I207 PolarHBondContact O-N 3.03Å; S205-V208 PolarHBondContact O-N 3.36Å; S205-V209 VanDerWaalsContact O-CG2 3.31Å; S205-V209 WeakPolarHBondContact O-CG2 3.48Å; S205-V209 PolarHBondContact O-N 3.4Å
206	M	95.9	Very high	94.8	Very high	0 Å²	0	26.3 Å²	26.3	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-60.6	-40.3	178.1	-66.5	172.6	-175.4	0	0	112.4	Y140 K202 F203 V209 L210 M274 L277 T278	Y140-M206 HydrophobicContact CD2-CB 4Å; Y140-M206 HydrophobicContact CE2-CB 4.25Å; Y140-M206 HydrophobicContact CE2-SD 4.36Å; K202-M206 HydrophobicContact CB-CE 4.29Å; K202-M206 HydrophobicContact CD-CE 3.81Å; K202-M206 HydrophobicContact CG-CE 3.74Å; K202-M206 WeakPolarHBondContact O-CG 3.38Å; K202-M206 PolarHBondContact O-N 3.25Å; F203-M206 HydrophobicContact CD1-SD 3.81Å; F203-M206 HydrophobicContact CE1-SD 4.19Å; F203-M206 PolarHBondContact O-N 2.81Å; M206-V209 WeakPolarHBondContact O-CB 3.19Å; M206-V209 PolarHBondContact O-N 3.25Å; M206-L210 WeakPolarHBondContact O-CG 3.13Å; M206-L210 PolarHBondContact O-N 2.81Å; M206-M274 HydrophobicContact CE-CB 4.36Å; M206-M274 HydrophobicContact CE-CG 3.88Å; M206-M274 HydrophobicContact CG-CG 4.13Å; M206-L277 HydrophobicContact CE-CB 4.09Å; M206-L277 HydrophobicContact CE-CD1 3.48Å; M206-L277 VanDerWaalsContact CE-CD1 3.48Å; M206-L277 HydrophobicContact CE-CG 4.4Å; M206-L277 HydrophobicContact SD-CB 4.4Å; M206-L277 HydrophobicContact SD-CD1 4.3Å; M206-T278 HydrophobicContact CB-CG2 3.92Å; M206-T278 HydrophobicContact CG-CG2 3.83Å
207	I	96.5	Very high	94.7	Very high	23 Å²	23	28.1 Å²	28.1	12%	0.118	16%	0.164	C	C	.	.	H	α-helix	trans	-59.4	-48.1	175.8	-69.8	161	0	0	0	110.7	A136 T139 L143 F203 V204 S205 V209 L210 I211	A136-I207 HydrophobicContact CB-CD1 3.86Å; A136-I207 WeakPolarHBondContact O-CD1 3.26Å; T139-I207 HydrophobicContact CG2-CD1 3.8Å; T139-I207 HydrophobicContact CG2-CG1 4.24Å; T139-I207 HydrophobicContact CG2-CG2 4.48Å; L143-I207 HydrophobicContact CD2-CG2 4.03Å; F203-I207 WeakPolarHBondContact O-CD1 3.36Å; F203-I207 VanDerWaalsContact O-CG1 3.28Å; F203-I207 WeakPolarHBondContact O-CG1 3.29Å; F203-I207 PolarHBondContact O-N 2.99Å; V204-I207 PolarHBondContact O-N 3.24Å; S205-I207 VanDerWaalsContact C-N 3.34Å; S205-I207 PolarHBondContact O-N 3.03Å; I207-V209 VanDerWaalsContact C-N 3.26Å; I207-V209 PolarHBondContact O-N 2.83Å; I207-L210 PolarHBondContact O-N 3.38Å; I207-L210 VanDerWaalsContact O-N 3.16Å; I207-I211 HydrophobicContact CG2-CD1 3.69Å; I207-I211 HydrophobicContact CG2-CG1 4.29Å; I207-I211 WeakPolarHBondContact O-CG1 3.26Å; I207-I211 PolarHBondContact O-N 3.3Å
208	V	96.3	Very high	94.7	Very high	42 Å²	42	35.5 Å²	35.5	26%	0.255	19%	0.192	S	C	.	.	H	α-helix	trans	-61	-38.6	179.5	172.9	0	0	0	0	111.5	L101 V204 S205 I211 S212 T228	L101-V208 HydrophobicContact CD1-CG2 3.85Å; L101-V208 HydrophobicContact CD2-CB 4.35Å; L101-V208 HydrophobicContact CD2-CG2 3.63Å; L101-V208 HydrophobicContact CG-CG2 4.4Å; V204-V208 PolarHBondContact O-N 3.2Å; S205-V208 PolarHBondContact O-N 3.36Å; V208-I211 PolarHBondContact O-N 3.45Å; V208-S212 WeakPolarHBondContact O-CB 3.31Å; V208-S212 PolarHBondContact O-N 2.89Å; V208-S212 PolarHBondContact O-OG 3.46Å; V208-T228 HydrophobicContact CB-CG2 4.19Å; V208-T228 HydrophobicContact CG1-CG2 3.91Å
209	V	96.4	Very high	94.7	Very high	0 Å²	0	38.7 Å²	38.7	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-62.4	-44.9	175.6	171.8	0	0	0	0	111.6	S205 M206 I207 S212 Y213 Y221 S224 L225 T228 T278	S205-V209 VanDerWaalsContact O-CG2 3.31Å; S205-V209 WeakPolarHBondContact O-CG2 3.48Å; S205-V209 PolarHBondContact O-N 3.4Å; M206-V209 WeakPolarHBondContact O-CB 3.19Å; M206-V209 PolarHBondContact O-N 3.25Å; I207-V209 VanDerWaalsContact C-N 3.26Å; I207-V209 PolarHBondContact O-N 2.83Å; V209-S212 PolarHBondContact O-N 2.89Å; V209-Y213 PolarHBondContact O-N 2.76Å; V209-Y221 HydrophobicContact CG1-CD2 3.22Å; V209-Y221 HydrophobicContact CG1-CE2 3.3Å; V209-Y221 HydrophobicContact CG1-CG 4.41Å; V209-S224 WeakPolarHBondContact CA-OG 3.4Å; V209-L225 HydrophobicContact CG1-CB 4.27Å; V209-L225 HydrophobicContact CG1-CD1 4.4Å; V209-L225 HydrophobicContact CG2-CB 4.26Å; V209-L225 HydrophobicContact CG2-CD1 4.32Å; V209-T228 HydrophobicContact CG2-CG2 4.42Å; V209-T228 VanDerWaalsContact CG2-OG1 3.29Å; V209-T228 WeakPolarHBondContact CG2-OG1 3.5Å; V209-T278 HydrophobicContact CG1-CG2 4.43Å
210	L	95.3	Very high	94.7	Very high	0 Å²	0	38.9 Å²	38.9	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-67.9	-39.3	177.7	-69.6	-174.6	0	0	0	112.7	Y140 L143 S144 I147 M206 I207 S212 Y213 I214 V281 I282	Y140-L210 HydrophobicContact CD2-CD1 3.71Å; Y140-L210 HydrophobicContact CE2-CD1 3.76Å; L143-L210 HydrophobicContact CD2-CB 3.58Å; L143-L210 HydrophobicContact CD2-CD1 4.17Å; L143-L210 HydrophobicContact CG-CB 4.18Å; L143-L210 HydrophobicContact CG-CD1 4.32Å; S144-L210 WeakPolarHBondContact OG-CD1 3.16Å; I147-L210 HydrophobicContact CD1-CB 3.88Å; I147-L210 HydrophobicContact CD1-CD1 4.23Å; I147-L210 HydrophobicContact CD1-CD2 3.87Å; I147-L210 HydrophobicContact CD1-CG 4.2Å; M206-L210 WeakPolarHBondContact O-CG 3.13Å; M206-L210 PolarHBondContact O-N 2.81Å; I207-L210 PolarHBondContact O-N 3.38Å; I207-L210 VanDerWaalsContact O-N 3.16Å; L210-S212 VanDerWaalsContact C-N 3.32Å; L210-S212 PolarHBondContact O-N 3.47Å; L210-Y213 WeakPolarHBondContact O-CB 3.43Å; L210-Y213 PolarHBondContact O-N 2.84Å; L210-I214 WeakPolarHBondContact O-CG1 3.07Å; L210-I214 PolarHBondContact O-N 3.12Å; L210-I214 VanDerWaalsContact O-N 3.07Å; L210-V281 HydrophobicContact CD1-CG1 4.4Å; L210-V281 HydrophobicContact CD2-CB 4.1Å; L210-V281 HydrophobicContact CD2-CG1 3.9Å; L210-I282 HydrophobicContact CD2-CD1 4.49Å; L210-I282 HydrophobicContact CD2-CG1 4.48Å
211	I	96.1	Very high	94.7	Very high	95 Å²	95	39.1 Å²	39.1	49%	0.487	22%	0.216	S	C	.	.	H	α-helix	trans	-63.3	-42	174.7	-67.6	171.9	0	0	0	110.4	L143 I207 V208 Y213 I214 G215	L143-I211 HydrophobicContact CD2-CG1 3.83Å; I207-I211 HydrophobicContact CG2-CD1 3.69Å; I207-I211 HydrophobicContact CG2-CG1 4.29Å; I207-I211 WeakPolarHBondContact O-CG1 3.26Å; I207-I211 PolarHBondContact O-N 3.3Å; V208-I211 PolarHBondContact O-N 3.45Å; I211-Y213 VanDerWaalsContact C-N 3.29Å; I211-Y213 PolarHBondContact O-N 3.24Å; I211-I214 PolarHBondContact O-N 2.9Å; I211-G215 PolarHBondContact O-N 3.08Å; I211-G215 VanDerWaalsContact O-N 3.16Å
212	S	95	Very high	94.7	Very high	31 Å²	31	45.7 Å²	45.7	22%	0.217	24%	0.242	C	C	.	.	H	α-helix	trans	-64.4	-35.3	177.1	-60.2	0	0	0	0	111.8	V208 V209 L210 G215 L216 S224	V208-S212 WeakPolarHBondContact O-CB 3.31Å; V208-S212 PolarHBondContact O-N 2.89Å; V208-S212 PolarHBondContact O-OG 3.46Å; V209-S212 PolarHBondContact O-N 2.89Å; L210-S212 VanDerWaalsContact C-N 3.32Å; L210-S212 PolarHBondContact O-N 3.47Å; S212-G215 PolarHBondContact O-N 3.46Å; S212-L216 WeakPolarHBondContact O-CB 3.48Å; S212-L216 PolarHBondContact O-N 2.86Å; S212-S224 WeakPolarHBondContact CB-OG 3.43Å; S212-S224 WeakPolarHBondContact OG-CB 3.28Å
213	Y	94.6	Very high	94.7	Very high	35 Å²	35	53.2 Å²	53.2	14%	0.137	28%	0.275	C	S	.	.	H	α-helix	trans	-63.8	-41.4	172.4	174.1	-109.3	0	0	0	112.3	I147 V209 L210 I211 G215 D217 I282	I147-Y213 HydrophobicContact CD1-CD1 4.32Å; I147-Y213 HydrophobicContact CG2-CD1 4.49Å; I147-Y213 HydrophobicContact CG2-CE1 4.07Å; V209-Y213 PolarHBondContact O-N 2.76Å; L210-Y213 WeakPolarHBondContact O-CB 3.43Å; L210-Y213 PolarHBondContact O-N 2.84Å; I211-Y213 VanDerWaalsContact C-N 3.29Å; I211-Y213 PolarHBondContact O-N 3.24Å; Y213-G215 VanDerWaalsContact C-N 3.33Å; Y213-G215 PolarHBondContact O-N 2.99Å; Y213-D217 VanDerWaalsContact CE2-OD1 3.29Å; Y213-D217 WeakPolarHBondContact CE2-OD1 2.99Å; Y213-D217 WeakPolarHBondContact O-CA 3.25Å; Y213-D217 PolarHBondContact O-N 2.81Å; Y213-I282 HydrophobicContact CD1-CG1 4.06Å; Y213-I282 HydrophobicContact CD2-CD1 4.29Å; Y213-I282 HydrophobicContact CD2-CG1 4.32Å; Y213-I282 HydrophobicContact CD2-CG2 4.17Å; Y213-I282 HydrophobicContact CE1-CG1 4.19Å; Y213-I282 HydrophobicContact CE2-CG1 4.46Å; Y213-I282 HydrophobicContact CE2-CG2 3.71Å; Y213-I282 HydrophobicContact CG-CD1 4.17Å; Y213-I282 HydrophobicContact CG-CG1 4.13Å
214	I	93.6	Very high	94.6	Very high	78 Å²	78	53.8 Å²	53.8	40%	0.4	28%	0.279	S	S	.	.	H	α-helix	trans	-63.2	-39.8	177.1	-65.3	166.8	0	0	0	111.3	L143 I147 L210 I211	L143-I214 HydrophobicContact CD1-CD1 3.85Å; I147-I214 HydrophobicContact CD1-CD1 4.16Å; I147-I214 HydrophobicContact CD1-CG1 4.18Å; I147-I214 HydrophobicContact CG1-CD1 3.83Å; I147-I214 HydrophobicContact CG1-CG1 3.91Å; L210-I214 WeakPolarHBondContact O-CG1 3.07Å; L210-I214 PolarHBondContact O-N 3.12Å; L210-I214 VanDerWaalsContact O-N 3.07Å; I211-I214 PolarHBondContact O-N 2.9Å
215	G	93.2	Very high	94.6	Very high	63 Å²	63	54 Å²	54	65%	0.649	28%	0.28	S	S	*	.	H	α-helix	trans	-83.4	-35.7	-176.1	0	0	0	0	0	115.3	I211 S212 Y213	I211-G215 PolarHBondContact O-N 3.08Å; I211-G215 VanDerWaalsContact O-N 3.16Å; S212-G215 PolarHBondContact O-N 3.46Å; Y213-G215 VanDerWaalsContact C-N 3.33Å; Y213-G215 PolarHBondContact O-N 2.99Å
216	L	93.6	Very high	94.5	Very high	120 Å²	120	59.3 Å²	59.3	63%	0.628	31%	0.308	S	S	*	.	H	α-helix	trans	-126.3	7.9	-169.7	-65.3	174.4	0	0	0	113	S212 P219	S212-L216 WeakPolarHBondContact O-CB 3.48Å; S212-L216 PolarHBondContact O-N 2.86Å; L216-P219 WeakPolarHBondContact O-CD 3.2Å; L216-P219 VanDerWaalsContact O-CG 3.22Å; L216-P219 WeakPolarHBondContact O-CG 3.24Å
217	D	90.9	Very high	94.5	Very high	84 Å²	84	63.7 Å²	63.7	45%	0.449	33%	0.325	S	S	.	.	H	α-helix	trans	55	-149.6	-177.9	-163.7	-1.6	0	0	0	112.1	Y213 G220 Y221	Y213-D217 VanDerWaalsContact CE2-OD1 3.29Å; Y213-D217 WeakPolarHBondContact CE2-OD1 2.99Å; Y213-D217 WeakPolarHBondContact O-CA 3.25Å; Y213-D217 PolarHBondContact O-N 2.81Å; D217-G220 PolarHBondContact O-N 3.48Å; D217-Y221 PolarHBondContact O-N 3.27Å; D217-Y221 VanDerWaalsContact O-N 3.08Å
218	R	91.7	Very high	94.5	Very high	155 Å²	155	62.7 Å²	62.7	59%	0.585	32%	0.32	S	S	*	.	H	α-helix	trans	-50.9	-44.9	-178.2	-62.9	-165.7	179.4	111.8	-0.6	115.6	Y221 Y222	R218-Y221 WeakPolarHBondContact O-CB 3.49Å; R218-Y221 PolarHBondContact O-N 3.49Å; R218-Y222 HydrophobicContact CB-CE2 4.4Å; R218-Y222 WeakPolarHBondContact O-CD2 3.28Å; R218-Y222 PolarHBondContact O-N 3.33Å; R218-Y222 VanDerWaalsContact O-N 3.16Å
219	P	92.9	Very high	94.4	Very high	72 Å²	72	61.2 Å²	61.2	47%	0.468	31%	0.311	S	S	.	.	H	α-helix	trans	-64.4	-42.4	179.3	23.6	-31.6	0	0	0	111.2	L216 Y221 Y222 F223	L216-P219 WeakPolarHBondContact O-CD 3.2Å; L216-P219 VanDerWaalsContact O-CG 3.22Å; L216-P219 WeakPolarHBondContact O-CG 3.24Å; P219-Y221 VanDerWaalsContact C-N 3.26Å; P219-Y221 PolarHBondContact O-N 2.91Å; P219-Y222 PolarHBondContact O-N 3.36Å; P219-F223 HydrophobicContact CB-CD2 4.35Å; P219-F223 HydrophobicContact CB-CE2 4.3Å; P219-F223 WeakPolarHBondContact O-CD2 3.43Å; P219-F223 PolarHBondContact O-N 2.77Å
220	G	93.1	Very high	94.3	Very high	5 Å²	5	66.1 Å²	66.1	5%	0.052	34%	0.337	C	S	.	.	H	α-helix	trans	-55.8	-42.4	174.6	0	0	0	0	0	112.9	D217 S224	D217-G220 PolarHBondContact O-N 3.48Å; G220-S224 WeakPolarHBondContact O-CB 3.14Å; G220-S224 PolarHBondContact O-N 2.87Å; G220-S224 PolarHBondContact O-OG 3.11Å
221	Y	94.4	Very high	94.3	Very high	6 Å²	6	66.1 Å²	66.1	2%	0.024	34%	0.337	C	S	.	.	H	α-helix	trans	-57.7	-54	174.8	171	-108.6	0	0	0	112.6	V209 D217 R218 P219 S224 L225 T278 I282	V209-Y221 HydrophobicContact CG1-CD2 3.22Å; V209-Y221 HydrophobicContact CG1-CE2 3.3Å; V209-Y221 HydrophobicContact CG1-CG 4.41Å; D217-Y221 PolarHBondContact O-N 3.27Å; D217-Y221 VanDerWaalsContact O-N 3.08Å; R218-Y221 WeakPolarHBondContact O-CB 3.49Å; R218-Y221 PolarHBondContact O-N 3.49Å; P219-Y221 VanDerWaalsContact C-N 3.26Å; P219-Y221 PolarHBondContact O-N 2.91Å; Y221-S224 PolarHBondContact O-OG 3.01Å; Y221-L225 HydrophobicContact CE1-CD2 4.22Å; Y221-L225 WeakPolarHBondContact O-CB 3.35Å; Y221-L225 PolarHBondContact O-N 2.78Å; Y221-T278 PolarHBondContact OH-OG1 3Å; Y221-I282 HydrophobicContact CD1-CD1 4.03Å; Y221-I282 HydrophobicContact CD2-CD1 2.98Å; Y221-I282 HydrophobicContact CD2-CG1 4.47Å; Y221-I282 HydrophobicContact CE1-CD1 4.06Å; Y221-I282 HydrophobicContact CE2-CD1 3.04Å; Y221-I282 HydrophobicContact CG-CD1 3.49Å; Y221-I282 VanDerWaalsContact CG-CD1 3.49Å
222	Y	94.3	Very high	94.2	Very high	138 Å²	138	61.6 Å²	61.6	54%	0.541	31%	0.314	S	S	.	.	H	α-helix	trans	-68.4	-39.5	-175.5	-69.2	-67.5	0	0	0	112.9	R218 P219 L225 L226	R218-Y222 HydrophobicContact CB-CE2 4.4Å; R218-Y222 WeakPolarHBondContact O-CD2 3.28Å; R218-Y222 PolarHBondContact O-N 3.33Å; R218-Y222 VanDerWaalsContact O-N 3.16Å; P219-Y222 PolarHBondContact O-N 3.36Å; Y222-L225 PolarHBondContact O-N 3.25Å; Y222-L226 WeakPolarHBondContact O-CB 3.46Å; Y222-L226 PolarHBondContact O-N 2.77Å
223	F	95.2	Very high	94.1	Very high	159 Å²	159	61 Å²	61	70%	0.697	31%	0.311	S	S	*	.	H	α-helix	trans	-65.6	-47.5	177.2	-76.8	-63.1	0	0	0	112	P219 L225 L226 Y227	P219-F223 HydrophobicContact CB-CD2 4.35Å; P219-F223 HydrophobicContact CB-CE2 4.3Å; P219-F223 WeakPolarHBondContact O-CD2 3.43Å; P219-F223 PolarHBondContact O-N 2.77Å; F223-L225 VanDerWaalsContact C-N 3.35Å; F223-L226 PolarHBondContact O-N 3.34Å; F223-Y227 WeakPolarHBondContact O-CB 3.29Å; F223-Y227 PolarHBondContact O-N 2.8Å
224	S	95.4	Very high	94	Very high	13 Å²	13	62.2 Å²	62.2	9%	0.091	32%	0.317	C	S	.	.	H	α-helix	trans	-65.8	-38.5	177.4	61	0	0	0	0	111.6	V209 S212 G220 Y221 Y227 T228	V209-S224 WeakPolarHBondContact CA-OG 3.4Å; S212-S224 WeakPolarHBondContact CB-OG 3.43Å; S212-S224 WeakPolarHBondContact OG-CB 3.28Å; G220-S224 WeakPolarHBondContact O-CB 3.14Å; G220-S224 PolarHBondContact O-N 2.87Å; G220-S224 PolarHBondContact O-OG 3.11Å; Y221-S224 PolarHBondContact O-OG 3.01Å; S224-Y227 PolarHBondContact O-N 3.07Å; S224-T228 VanDerWaalsContact O-CB 3.3Å; S224-T228 WeakPolarHBondContact O-CB 3.5Å; S224-T228 VanDerWaalsContact O-CG2 3.28Å; S224-T228 WeakPolarHBondContact O-CG2 3.4Å; S224-T228 PolarHBondContact O-N 3.09Å; S224-T228 PolarHBondContact O-OG1 3.37Å
225	L	95.3	Very high	94	Very high	16 Å²	16	58.5 Å²	58.5	8%	0.084	30%	0.298	C	S	.	.	H	α-helix	trans	-61.1	-48	177.3	-178.7	70.6	0	0	0	110.7	V209 Y221 Y222 F223 T228 S229 M274 W275	V209-L225 HydrophobicContact CG1-CB 4.27Å; V209-L225 HydrophobicContact CG1-CD1 4.4Å; V209-L225 HydrophobicContact CG2-CB 4.26Å; V209-L225 HydrophobicContact CG2-CD1 4.32Å; Y221-L225 HydrophobicContact CE1-CD2 4.22Å; Y221-L225 WeakPolarHBondContact O-CB 3.35Å; Y221-L225 PolarHBondContact O-N 2.78Å; Y222-L225 PolarHBondContact O-N 3.25Å; F223-L225 VanDerWaalsContact C-N 3.35Å; L225-T228 PolarHBondContact O-OG1 2.57Å; L225-S229 WeakPolarHBondContact O-CB 3.5Å; L225-S229 PolarHBondContact O-N 3.47Å; L225-S229 PolarHBondContact O-OG 2.88Å; L225-M274 HydrophobicContact CD1-CB 4.15Å; L225-M274 HydrophobicContact CD1-CE 4.01Å; L225-W275 HydrophobicContact CD2-CB 4.11Å; L225-W275 HydrophobicContact CD2-CG 4.31Å
226	L	95.6	Very high	93.9	Very high	111 Å²	111	55.5 Å²	55.5	58%	0.581	27%	0.267	S	S	*	.	H	α-helix	trans	-61.7	-49.4	177.7	-179.6	62	0	0	0	111.3	Y222 F223 S229 L230	Y222-L226 WeakPolarHBondContact O-CB 3.46Å; Y222-L226 PolarHBondContact O-N 2.77Å; F223-L226 PolarHBondContact O-N 3.34Å; L226-S229 PolarHBondContact O-N 2.91Å; L226-L230 HydrophobicContact CD1-CD1 4.26Å; L226-L230 HydrophobicContact CG-CD1 4.38Å; L226-L230 WeakPolarHBondContact O-CG 3.44Å; L226-L230 PolarHBondContact O-N 3.01Å; L226-L230 VanDerWaalsContact O-N 3.11Å
227	Y	96.2	Very high	93.7	Very high	92 Å²	92	52.8 Å²	52.8	36%	0.361	25%	0.252	S	S	.	.	H	α-helix	trans	-61	-54.1	-178.9	177.5	-96.6	0	0	0	112.2	L101 F102 F104 F223 S224 S229 L230 A231	L101-Y227 WeakPolarHBondContact O-CE1 3.33Å; L101-Y227 PolarHBondContact O-OH 2.94Å; F102-Y227 WeakPolarHBondContact CD1-OH 3.23Å; F102-Y227 HydrophobicContact CE1-CE1 4.46Å; F102-Y227 VanDerWaalsContact CE1-OH 3.31Å; F102-Y227 WeakPolarHBondContact CE1-OH 3.25Å; F104-Y227 HydrophobicContact CE2-CE2 4.35Å; F223-Y227 WeakPolarHBondContact O-CB 3.29Å; F223-Y227 PolarHBondContact O-N 2.8Å; S224-Y227 PolarHBondContact O-N 3.07Å; Y227-S229 VanDerWaalsContact C-N 3.28Å; Y227-S229 PolarHBondContact O-N 3.31Å; Y227-L230 PolarHBondContact O-N 2.91Å; Y227-A231 WeakPolarHBondContact O-CB 3.4Å; Y227-A231 PolarHBondContact O-N 3.22Å
228	T	95.6	Very high	93.6	Very high	2 Å²	2	54 Å²	54	1%	0.012	25%	0.251	C	S	.	.	H	α-helix	trans	-67.9	-28.6	-176.7	59.1	0	0	0	0	112.3	L101 V208 V209 S224 L225 L232 M274	L101-T228 HydrophobicContact CD2-CG2 4.47Å; V208-T228 HydrophobicContact CB-CG2 4.19Å; V208-T228 HydrophobicContact CG1-CG2 3.91Å; V209-T228 HydrophobicContact CG2-CG2 4.42Å; V209-T228 VanDerWaalsContact CG2-OG1 3.29Å; V209-T228 WeakPolarHBondContact CG2-OG1 3.5Å; S224-T228 VanDerWaalsContact O-CB 3.3Å; S224-T228 WeakPolarHBondContact O-CB 3.5Å; S224-T228 VanDerWaalsContact O-CG2 3.28Å; S224-T228 WeakPolarHBondContact O-CG2 3.4Å; S224-T228 PolarHBondContact O-N 3.09Å; S224-T228 PolarHBondContact O-OG1 3.37Å; L225-T228 PolarHBondContact O-OG1 2.57Å; T228-L232 WeakPolarHBondContact O-CB 3.15Å; T228-L232 PolarHBondContact O-N 3.33Å; T228-M274 WeakPolarHBondContact OG1-CE 3.44Å
229	S	94.4	Very high	93.3	Very high	10 Å²	10	47 Å²	47	7%	0.07	23%	0.225	C	C	.	.	H	α-helix	trans	-65.7	-46.4	172.1	-67.1	0	0	0	0	111.8	L225 L226 Y227 A233 M274	L225-S229 WeakPolarHBondContact O-CB 3.5Å; L225-S229 PolarHBondContact O-N 3.47Å; L225-S229 PolarHBondContact O-OG 2.88Å; L226-S229 PolarHBondContact O-N 2.91Å; Y227-S229 VanDerWaalsContact C-N 3.28Å; Y227-S229 PolarHBondContact O-N 3.31Å; S229-A233 VanDerWaalsContact O-CB 3.31Å; S229-A233 WeakPolarHBondContact O-CB 3.36Å; S229-A233 PolarHBondContact O-N 3.28Å; S229-M274 VanDerWaalsContact OG-CE 3.31Å; S229-M274 WeakPolarHBondContact OG-CE 3.25Å
230	L	94.2	Very high	92.8	Very high	104 Å²	104	44 Å²	44	55%	0.545	21%	0.205	S	C	.	.	H	α-helix	trans	-66.7	-42.3	177.4	-69.8	174.5	0	0	0	111.6	L226 Y227 F234	L226-L230 HydrophobicContact CD1-CD1 4.26Å; L226-L230 HydrophobicContact CG-CD1 4.38Å; L226-L230 WeakPolarHBondContact O-CG 3.44Å; L226-L230 PolarHBondContact O-N 3.01Å; L226-L230 VanDerWaalsContact O-N 3.11Å; Y227-L230 PolarHBondContact O-N 2.91Å; L230-F234 WeakPolarHBondContact O-CB 3.42Å; L230-F234 PolarHBondContact O-N 3.43Å
231	A	94.9	Very high	92.3	Very high	0 Å²	0	48.4 Å²	48.4	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-58.6	-53.6	174.3	0	0	0	0	0	110.7	P103 F104 Y227 A233 F234 F235	P103-A231 HydrophobicContact CG-CB 3.93Å; P103-A231 VanDerWaalsContact CG-O 3.27Å; P103-A231 WeakPolarHBondContact CG-O 3.45Å; F104-A231 HydrophobicContact CE2-CB 4.16Å; F104-A231 HydrophobicContact CZ-CB 4.34Å; Y227-A231 WeakPolarHBondContact O-CB 3.4Å; Y227-A231 PolarHBondContact O-N 3.22Å; A231-A233 PolarHBondContact O-N 2.84Å; A231-F234 PolarHBondContact O-N 2.77Å; A231-F235 WeakPolarHBondContact O-CB 3.1Å; A231-F235 PolarHBondContact O-N 2.83Å
232	L	94.4	Very high	91.2	Very high	0 Å²	0	51.6 Å²	51.6	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-60.7	-44.7	-179.6	-176.1	69.3	0	0	0	112.4	I100 K202 T228 F234 F235 L236 Q270 M274	I100-L232 HydrophobicContact CG2-CD1 4.29Å; K202-L232 HydrophobicContact CB-CD2 3.63Å; T228-L232 WeakPolarHBondContact O-CB 3.15Å; T228-L232 PolarHBondContact O-N 3.33Å; L232-F234 VanDerWaalsContact C-N 3.34Å; L232-F234 PolarHBondContact O-N 3.03Å; L232-F235 HydrophobicContact CD1-CD1 4.46Å; L232-F235 PolarHBondContact O-N 2.77Å; L232-L236 HydrophobicContact CD1-CD1 4.49Å; L232-L236 HydrophobicContact CD1-CG 4.41Å; L232-L236 HydrophobicContact CG-CD1 4.17Å; L232-L236 HydrophobicContact CG-CG 4.46Å; L232-L236 WeakPolarHBondContact O-CB 3.22Å; L232-L236 WeakPolarHBondContact O-CG 3.24Å; L232-L236 PolarHBondContact O-N 3.14Å; L232-Q270 HydrophobicContact CD2-CB 3.88Å; L232-Q270 HydrophobicContact CD2-CG 4.11Å; L232-M274 HydrophobicContact CD2-SD 3.56Å; L232-M274 VanDerWaalsContact CD2-SD 3.56Å
233	A	93.2	Very high	90.1	Very high	18 Å²	18	47.3 Å²	47.3	15%	0.149	22%	0.224	C	C	.	.	H	α-helix	trans	-59.8	-44.9	176.7	0	0	0	0	0	111.4	S229 A231 L236 I237 A267	S229-A233 VanDerWaalsContact O-CB 3.31Å; S229-A233 WeakPolarHBondContact O-CB 3.36Å; S229-A233 PolarHBondContact O-N 3.28Å; A231-A233 PolarHBondContact O-N 2.84Å; A233-L236 PolarHBondContact O-N 3.04Å; A233-I237 WeakPolarHBondContact O-CB 3.29Å; A233-I237 WeakPolarHBondContact O-CD1 3.14Å; A233-I237 WeakPolarHBondContact O-CG1 3.22Å; A233-I237 PolarHBondContact O-N 2.83Å; A233-A267 HydrophobicContact CB-CB 4.44Å
234	F	92.5	Very high	88.9	Confident	60 Å²	60	40 Å²	40	26%	0.263	19%	0.192	S	C	.	.	H	α-helix	trans	-64.6	-44.1	177	-178.1	-91.5	0	0	0	112.3	P103 F104 W109 L230 A231 L232 I237 R238	P103-F234 HydrophobicContact CB-CD1 3.84Å; P103-F234 HydrophobicContact CB-CE1 4.36Å; P103-F234 HydrophobicContact CG-CD1 3.96Å; F104-F234 AromaticContact CD1-CD1 3.94Å; F104-F234 HydrophobicContact CD1-CD1 3.94Å; F104-F234 HydrophobicContact CD1-CD2 4.34Å; F104-F234 HydrophobicContact CD1-CE1 4.15Å; F104-F234 HydrophobicContact CD1-CG 4.02Å; F104-F234 HydrophobicContact CD1-CZ 4.44Å; F104-F234 HydrophobicContact CE1-CB 3.83Å; F104-F234 HydrophobicContact CE1-CD1 4.08Å; F104-F234 HydrophobicContact CE1-CD2 4.18Å; F104-F234 AromaticContact CE1-CG 3.78Å; F104-F234 HydrophobicContact CE1-CG 3.78Å; F104-F234 HydrophobicContact CZ-CB 4.48Å; W109-F234 HydrophobicContact CZ2-CD1 4.44Å; W109-F234 AromaticContact CZ2-CE1 3.92Å; W109-F234 HydrophobicContact CZ2-CE1 3.92Å; L230-F234 WeakPolarHBondContact O-CB 3.42Å; L230-F234 PolarHBondContact O-N 3.43Å; A231-F234 PolarHBondContact O-N 2.77Å; L232-F234 VanDerWaalsContact C-N 3.34Å; L232-F234 PolarHBondContact O-N 3.03Å; F234-I237 PolarHBondContact O-N 2.79Å; F234-R238 HydrophobicContact CD1-CG 4.12Å; F234-R238 HydrophobicContact CE1-CG 3.78Å; F234-R238 HydrophobicContact CE2-CG 4.35Å; F234-R238 HydrophobicContact CZ-CG 3.91Å; F234-R238 WeakPolarHBondContact O-CB 3.22Å; F234-R238 VanDerWaalsContact O-CG 3.31Å; F234-R238 WeakPolarHBondContact O-CG 3.26Å; F234-R238 PolarHBondContact O-N 3.44Å
235	F	93.3	Very high	87.6	Confident	0 Å²	0	40.5 Å²	40.5	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-56.6	-51.4	174.7	169.4	-98.9	0	0	0	111.2	L99 I100 P103 W109 Y201 A231 L232 I237 R238 S239	L99-F235 HydrophobicContact CD2-CD2 4.43Å; L99-F235 HydrophobicContact CD2-CE2 3.86Å; L99-F235 HydrophobicContact CG-CD2 4.08Å; L99-F235 HydrophobicContact CG-CE2 3.94Å; I100-F235 HydrophobicContact CG1-CD1 4.38Å; I100-F235 HydrophobicContact CG1-CD2 4.38Å; I100-F235 HydrophobicContact CG1-CE1 4.07Å; I100-F235 HydrophobicContact CG1-CE2 4.08Å; I100-F235 HydrophobicContact CG1-CZ 3.91Å; P103-F235 HydrophobicContact CB-CB 3.94Å; P103-F235 HydrophobicContact CG-CB 4.18Å; W109-F235 AromaticContact CH2-CD2 3.97Å; W109-F235 HydrophobicContact CH2-CD2 3.97Å; W109-F235 AromaticContact CZ3-CD2 3.85Å; W109-F235 HydrophobicContact CZ3-CD2 3.85Å; W109-F235 HydrophobicContact CZ3-CE2 4.29Å; Y201-F235 AromaticContact CD2-CE1 3.64Å; Y201-F235 HydrophobicContact CD2-CE1 3.64Å; Y201-F235 HydrophobicContact CD2-CZ 4.19Å; Y201-F235 HydrophobicContact CE2-CE1 4.07Å; Y201-F235 HydrophobicContact CE2-CZ 4.19Å; Y201-F235 HydrophobicContact CG-CE1 4.21Å; A231-F235 WeakPolarHBondContact O-CB 3.1Å; A231-F235 PolarHBondContact O-N 2.83Å; L232-F235 HydrophobicContact CD1-CD1 4.46Å; L232-F235 PolarHBondContact O-N 2.77Å; F235-I237 PolarHBondContact O-N 3.49Å; F235-R238 PolarHBondContact O-N 2.72Å; F235-S239 WeakPolarHBondContact CE2-OG 2.98Å; F235-S239 WeakPolarHBondContact O-CB 3.48Å; F235-S239 PolarHBondContact O-N 3.4Å; F235-S239 PolarHBondContact O-OG 2.8Å
236	L	91.5	Very high	86	Confident	1 Å²	1	43 Å²	43	1%	0.005	21%	0.211	C	C	.	.	H	α-helix	trans	-62.1	-44.4	179.4	-71.9	176.1	0	0	0	112.1	Y198 L232 A233 R238 S239 L240 Q270	Y198-L236 HydrophobicContact CD1-CD2 3.9Å; Y198-L236 HydrophobicContact CG-CD2 4.32Å; L232-L236 HydrophobicContact CD1-CD1 4.49Å; L232-L236 HydrophobicContact CD1-CG 4.41Å; L232-L236 HydrophobicContact CG-CD1 4.17Å; L232-L236 HydrophobicContact CG-CG 4.46Å; L232-L236 WeakPolarHBondContact O-CB 3.22Å; L232-L236 WeakPolarHBondContact O-CG 3.24Å; L232-L236 PolarHBondContact O-N 3.14Å; A233-L236 PolarHBondContact O-N 3.04Å; L236-R238 VanDerWaalsContact C-N 3.3Å; L236-R238 PolarHBondContact O-N 2.95Å; L236-S239 PolarHBondContact O-N 3.45Å; L236-L240 HydrophobicContact CB-CD1 4.41Å; L236-L240 WeakPolarHBondContact O-CB 3.29Å; L236-L240 WeakPolarHBondContact O-CG 3.21Å; L236-L240 PolarHBondContact O-N 2.82Å; L236-Q270 HydrophobicContact CD1-CG 3.37Å
237	I	89.5	Confident	84.4	Confident	63 Å²	63	42.7 Å²	42.7	32%	0.323	21%	0.206	S	C	.	.	H	α-helix	trans	-57.3	-46.7	176.6	-72	162.7	0	0	0	110.1	A233 F234 F235 K241 L263 A267	A233-I237 WeakPolarHBondContact O-CB 3.29Å; A233-I237 WeakPolarHBondContact O-CD1 3.14Å; A233-I237 WeakPolarHBondContact O-CG1 3.22Å; A233-I237 PolarHBondContact O-N 2.83Å; F234-I237 PolarHBondContact O-N 2.79Å; F235-I237 PolarHBondContact O-N 3.49Å; I237-K241 WeakPolarHBondContact O-CB 3.18Å; I237-K241 PolarHBondContact O-N 2.74Å; I237-L263 HydrophobicContact CB-CD2 3.95Å; I237-L263 HydrophobicContact CG1-CD2 3.58Å; I237-L263 HydrophobicContact CG2-CD2 4Å; I237-A267 HydrophobicContact CD1-CB 4.06Å; I237-A267 HydrophobicContact CG1-CB 3.74Å
238	R	88	Confident	82.7	Confident	109 Å²	109	42.2 Å²	42.2	41%	0.411	21%	0.213	S	C	.	.	H	α-helix	trans	-69.5	-47.4	-177.9	-72	-71.5	-175.4	171.3	1.6	112.4	W109 F234 F235 L236	W109-R238 HydrophobicContact CD2-CB 3.58Å; W109-R238 HydrophobicContact CD2-CG 4.2Å; W109-R238 HydrophobicContact CE3-CB 3.48Å; W109-R238 VanDerWaalsContact CE3-CB 3.48Å; W109-R238 HydrophobicContact CG-CB 4.35Å; W109-R238 HydrophobicContact CH2-CB 3.69Å; W109-R238 HydrophobicContact CH2-CG 4.2Å; W109-R238 HydrophobicContact CZ2-CB 3.79Å; W109-R238 HydrophobicContact CZ2-CG 3.88Å; W109-R238 HydrophobicContact CZ3-CB 3.53Å; W109-R238 HydrophobicContact CZ3-CG 4.5Å; F234-R238 HydrophobicContact CD1-CG 4.12Å; F234-R238 HydrophobicContact CE1-CG 3.78Å; F234-R238 HydrophobicContact CE2-CG 4.35Å; F234-R238 HydrophobicContact CZ-CG 3.91Å; F234-R238 WeakPolarHBondContact O-CB 3.22Å; F234-R238 VanDerWaalsContact O-CG 3.31Å; F234-R238 WeakPolarHBondContact O-CG 3.26Å; F234-R238 PolarHBondContact O-N 3.44Å; F235-R238 PolarHBondContact O-N 2.72Å; L236-R238 VanDerWaalsContact C-N 3.3Å; L236-R238 PolarHBondContact O-N 2.95Å
239	S	86.2	Confident	81.1	Confident	7 Å²	7	51.5 Å²	51.5	5%	0.049	26%	0.256	C	S	.	.	H	α-helix	trans	-67.7	-44.5	-179	-62.8	0	0	0	0	112.8	F235 L236	F235-S239 WeakPolarHBondContact CE2-OG 2.98Å; F235-S239 WeakPolarHBondContact O-CB 3.48Å; F235-S239 PolarHBondContact O-N 3.4Å; F235-S239 PolarHBondContact O-OG 2.8Å; L236-S239 PolarHBondContact O-N 3.45Å
240	L	82.1	Confident	79.5	Confident	9 Å²	9	52 Å²	52	5%	0.047	26%	0.261	C	S	.	.	H	α-helix	trans	-73.4	-34.6	-179.7	-72.2	168.4	0	0	0	112.2	Y198 L236 L242 K243 I244 L263 I266	Y198-L240 HydrophobicContact CD1-CD2 4.47Å; Y198-L240 HydrophobicContact CD1-CG 4.49Å; Y198-L240 HydrophobicContact CD2-CD2 3.42Å; Y198-L240 VanDerWaalsContact CD2-CD2 3.42Å; Y198-L240 HydrophobicContact CD2-CG 4.26Å; Y198-L240 HydrophobicContact CE2-CD2 3.68Å; Y198-L240 HydrophobicContact CG-CD2 3.88Å; Y198-L240 HydrophobicContact CG-CG 4.27Å; L236-L240 HydrophobicContact CB-CD1 4.41Å; L236-L240 WeakPolarHBondContact O-CB 3.29Å; L236-L240 WeakPolarHBondContact O-CG 3.21Å; L236-L240 PolarHBondContact O-N 2.82Å; L240-L242 PolarHBondContact O-N 2.79Å; L240-K243 PolarHBondContact O-N 2.84Å; L240-K243 VanDerWaalsContact O-N 3.11Å; L240-I244 HydrophobicContact CB-CD1 4Å; L240-I244 HydrophobicContact CD2-CD1 4.45Å; L240-I244 WeakPolarHBondContact O-CB 2.98Å; L240-I244 VanDerWaalsContact O-CG1 3.28Å; L240-I244 WeakPolarHBondContact O-CG1 3.25Å; L240-I244 PolarHBondContact O-N 3.47Å; L240-L263 HydrophobicContact CB-CD1 3.77Å; L240-L263 HydrophobicContact CB-CG 4.21Å; L240-I266 HydrophobicContact CD1-CG2 4.24Å
241	K	82.4	Confident	78.1	Confident	98 Å²	98	48.3 Å²	48.3	43%	0.426	24%	0.24	S	C	.	.	H	α-helix	trans	-57.3	-39.6	179.4	178	177.4	179.3	179.9	0	111.3	I237 L245 L263	I237-K241 WeakPolarHBondContact O-CB 3.18Å; I237-K241 PolarHBondContact O-N 2.74Å; K241-L245 WeakPolarHBondContact O-CA 3.18Å; K241-L245 WeakPolarHBondContact O-CB 3.48Å; K241-L245 PolarHBondContact O-N 2.88Å; K241-L263 HydrophobicContact CB-CD1 3.87Å
242	L	70.7	Confident	76.7	Confident	73 Å²	73	51.4 Å²	51.4	38%	0.382	26%	0.26	S	S	.	.	H	α-helix	trans	-69.8	-33.6	179.5	-69.3	174.1	0	0	0	113.3	W109 L240	W109-L242 HydrophobicContact CB-CD1 3.42Å; W109-L242 VanDerWaalsContact CB-CD1 3.42Å; W109-L242 WeakPolarHBondContact O-CD1 3.45Å; L240-L242 PolarHBondContact O-N 2.79Å
243	K	72.5	Confident	75.6	Confident	49 Å²	49	55.1 Å²	55.1	21%	0.213	29%	0.286	C	S	.	.	H	α-helix	trans	-78.6	-36.6	177.1	-72	-165.5	164.9	-160.1	0	113.5	I190 D194 Y198 L240	I190-K243 HydrophobicContact CD1-CB 4.09Å; I190-K243 HydrophobicContact CG1-CB 4.33Å; D194-K243 VanDerWaalsContact CG-NZ 3.29Å; D194-K243 IonicContact OD1-NZ 3.51Å; D194-K243 IonicContact OD2-NZ 3.68Å; D194-K243 PolarHBondContact OD2-NZ 2.72Å; Y198-K243 HydrophobicContact CE2-CD 3.98Å; Y198-K243 WeakPolarHBondContact OH-CD 3.23Å; Y198-K243 WeakPolarHBondContact OH-CE 3.16Å; L240-K243 PolarHBondContact O-N 2.84Å; L240-K243 VanDerWaalsContact O-N 3.11Å
244	I	69	Low	74.6	Confident	4 Å²	4	59.2 Å²	59.2	2%	0.021	30%	0.302	C	S	.	.	H	α-helix	trans	-85.2	-29.1	-176.1	-58.4	169.5	0	0	0	110.9	I190 L240 P246 R259 L262 L263	I190-I244 HydrophobicContact CD1-CD1 4.4Å; I190-I244 HydrophobicContact CD1-CG1 3.45Å; I190-I244 VanDerWaalsContact CD1-CG1 3.45Å; L240-I244 HydrophobicContact CB-CD1 4Å; L240-I244 HydrophobicContact CD2-CD1 4.45Å; L240-I244 WeakPolarHBondContact O-CB 2.98Å; L240-I244 VanDerWaalsContact O-CG1 3.28Å; L240-I244 WeakPolarHBondContact O-CG1 3.25Å; L240-I244 PolarHBondContact O-N 3.47Å; I244-P246 WeakPolarHBondContact O-CD 3.24Å; I244-R259 HydrophobicContact CG2-CB 3.57Å; I244-R259 HydrophobicContact CG2-CG 3.58Å; I244-R259 PolarHBondContact O-NH1 3.26Å; I244-L262 HydrophobicContact CD1-CD2 4.43Å; I244-L263 HydrophobicContact CD1-CB 4.44Å; I244-L263 HydrophobicContact CD1-CD1 4.38Å
245	L	69.1	Low	73.7	Confident	24 Å²	24	56.6 Å²	56.6	13%	0.126	29%	0.291	C	S	.	.			trans	-121.2	61.7	178.5	-69.5	77.4	0	0	0	111.4	K241 H247 V248 N256 R259	K241-L245 WeakPolarHBondContact O-CA 3.18Å; K241-L245 WeakPolarHBondContact O-CB 3.48Å; K241-L245 PolarHBondContact O-N 2.88Å; L245-H247 PolarHBondContact O-N 3.46Å; L245-V248 HydrophobicContact CB-CG2 4.07Å; L245-V248 HydrophobicContact CD2-CG2 4.18Å; L245-N256 HydrophobicContact CD2-CB 4.38Å; L245-R259 HydrophobicContact CD1-CB 4.06Å
246	P	61.2	Low	72.9	Confident	68 Å²	68	57.6 Å²	57.6	44%	0.442	30%	0.297	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.7	-27.8	176.7	27.8	-33.7	0	0	0	112.1	I244	I244-P246 WeakPolarHBondContact O-CD 3.24Å
247	H	61.1	Low	72.4	Confident	106 Å²	106	62 Å²	62	49%	0.491	32%	0.316	S	S	.	.	T	Hydrogen-bonded Turn	trans	-136	78.7	-179.1	-53.6	-60	0	0	0	109.9	L245 E249 A250 Y251	L245-H247 PolarHBondContact O-N 3.46Å; H247-E249 PolarHBondContact O-N 3.46Å; H247-A250 HydrophobicContact CB-CB 3.6Å; H247-A250 PolarHBondContact O-N 2.86Å; H247-Y251 WeakPolarHBondContact O-CD2 3.49Å
248	V	61.6	Low	72.1	Confident	82 Å²	82	64.6 Å²	64.6	50%	0.497	32%	0.321	S	S	.	.	T	Hydrogen-bonded Turn	trans	-52.5	-31.1	178.1	-175.5	0	0	0	0	111.2	L245 N256	L245-V248 HydrophobicContact CB-CG2 4.07Å; L245-V248 HydrophobicContact CD2-CG2 4.18Å; V248-N256 PolarHBondContact O-ND2 3.35Å
249	E	61.9	Low	71.8	Confident	196 Å²	196	59.6 Å²	59.6	92%	0.916	30%	0.303	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80	-21.9	-178.2	-57.3	-176	174.1	0	0	114.4	H247 Y251	H247-E249 PolarHBondContact O-N 3.46Å; E249-Y251 VanDerWaalsContact C-N 3.35Å
250	A	61.1	Low	71.8	Confident	22 Å²	22	63.6 Å²	63.6	18%	0.182	32%	0.323	C	S	.	.	T	Hydrogen-bonded Turn	trans	-81.9	-13.6	-175.8	0	0	0	0	0	113.7	Y4 H247	Y4-A250 HydrophobicContact CE1-CB 4.42Å; H247-A250 HydrophobicContact CB-CB 3.6Å; H247-A250 PolarHBondContact O-N 2.86Å
251	Y	63.4	Low	72	Confident	26 Å²	26	71.1 Å²	71.1	10%	0.102	35%	0.352	C	S	.	.	S	Bend	trans	-118.2	142.1	-173.8	-66.6	-83.2	0	0	0	112.2	Y4 H247 E249	Y4-Y251 HydrophobicContact CD2-CE1 4.21Å; Y4-Y251 HydrophobicContact CE2-CE1 4.11Å; Y4-Y251 AromaticContact CE2-CZ 3.73Å; Y4-Y251 WeakPolarHBondContact CE2-OH 3.27Å; H247-Y251 WeakPolarHBondContact O-CD2 3.49Å; E249-Y251 VanDerWaalsContact C-N 3.35Å
252	P	66.9	Low	72.2	Confident	65 Å²	65	66.9 Å²	66.9	42%	0.422	33%	0.334	S	S	.	.			trans	-57.7	143	172.3	23	-31.5	0	0	0	110.5	E254 C255	P252-E254 PolarHBondContact O-N 2.71Å; P252-C255 HydrophobicContact CG-CB 4.37Å; P252-C255 VanDerWaalsContact O-CB 3.28Å; P252-C255 WeakPolarHBondContact O-CB 3.46Å; P252-C255 PolarHBondContact O-N 2.78Å
253	S	71.6	Confident	73	Confident	77 Å²	77	63.5 Å²	63.5	54%	0.538	32%	0.316	S	S	.	.	H	α-helix	trans	-51.7	-34.6	-173.4	58	0	0	0	0	113.8	C255 N256 K257	S253-C255 VanDerWaalsContact C-N 3.33Å; S253-C255 PolarHBondContact O-N 2.67Å; S253-N256 PolarHBondContact O-N 3.34Å; S253-K257 WeakPolarHBondContact O-CG 3.04Å; S253-K257 PolarHBondContact O-N 3.37Å
254	E	72.2	Confident	73.8	Confident	105 Å²	105	66 Å²	66	49%	0.491	33%	0.331	S	S	.	.	H	α-helix	trans	-62	-35.4	176.2	-66.5	-55.9	135.6	0	0	113.5	P252 K257 R258	P252-E254 PolarHBondContact O-N 2.71Å; E254-K257 PolarHBondContact O-N 3.38Å; E254-K257 IonicContact OE1-NZ 3.69Å; E254-K257 PolarHBondContact OE1-NZ 2.72Å; E254-K257 IonicContact OE2-NZ 2.72Å; E254-R258 WeakPolarHBondContact O-CG 3.24Å; E254-R258 PolarHBondContact O-N 2.95Å
255	C	72.1	Confident	74.8	Confident	5 Å²	5	70 Å²	70	3%	0.034	35%	0.352	C	S	.	.	H	α-helix	trans	-66.4	-43.9	175	-173	0	0	0	0	110.9	C2 P252 S253 K257 R258 R259	C2-C255 HydrophobicContact CB-CB 4Å; C2-C255 VanDerWaalsContact SG-CB 3.57Å; P252-C255 HydrophobicContact CG-CB 4.37Å; P252-C255 VanDerWaalsContact O-CB 3.28Å; P252-C255 WeakPolarHBondContact O-CB 3.46Å; P252-C255 PolarHBondContact O-N 2.78Å; S253-C255 VanDerWaalsContact C-N 3.33Å; S253-C255 PolarHBondContact O-N 2.67Å; C255-K257 VanDerWaalsContact C-N 3.31Å; C255-K257 PolarHBondContact O-N 2.96Å; C255-R258 PolarHBondContact O-N 3.1Å; C255-R259 WeakPolarHBondContact O-CG 3.17Å; C255-R259 PolarHBondContact O-N 3.04Å; C255-R259 VanDerWaalsContact O-N 3.09Å; C255-R259 PolarHBondContact SG-NE 3.2Å; C255-R259 VanDerWaalsContact SG-NE 3.36Å
256	N	77.5	Confident	75.8	Confident	21 Å²	21	69.5 Å²	69.5	11%	0.112	35%	0.35	C	S	.	.	H	α-helix	trans	-63.2	-37.9	178.5	-67.6	-22.8	0	0	0	111.5	L245 V248 S253 R259 L260	L245-N256 HydrophobicContact CD2-CB 4.38Å; V248-N256 PolarHBondContact O-ND2 3.35Å; S253-N256 PolarHBondContact O-N 3.34Å; N256-R259 PolarHBondContact O-N 3.49Å; N256-L260 WeakPolarHBondContact O-CB 3.34Å; N256-L260 PolarHBondContact O-N 3.17Å
257	K	81.6	Confident	77.2	Confident	93 Å²	93	66.5 Å²	66.5	40%	0.404	33%	0.33	S	S	.	.	H	α-helix	trans	-60.1	-49.5	174	-70.2	175.3	-172.3	171.7	0	111.8	S253 E254 C255 R259 L260 Y261	S253-K257 WeakPolarHBondContact O-CG 3.04Å; S253-K257 PolarHBondContact O-N 3.37Å; E254-K257 PolarHBondContact O-N 3.38Å; E254-K257 IonicContact OE1-NZ 3.69Å; E254-K257 PolarHBondContact OE1-NZ 2.72Å; E254-K257 IonicContact OE2-NZ 2.72Å; C255-K257 VanDerWaalsContact C-N 3.31Å; C255-K257 PolarHBondContact O-N 2.96Å; K257-R259 PolarHBondContact O-N 3.23Å; K257-L260 WeakPolarHBondContact O-CB 3.32Å; K257-L260 PolarHBondContact O-N 3.39Å; K257-L260 VanDerWaalsContact O-N 3.17Å; K257-Y261 HydrophobicContact CB-CD2 4.49Å; K257-Y261 HydrophobicContact CB-CE2 4.13Å; K257-Y261 WeakPolarHBondContact O-CD2 3.31Å; K257-Y261 PolarHBondContact O-N 3.33Å
258	R	82	Confident	78.5	Confident	117 Å²	117	68.1 Å²	68.1	44%	0.442	34%	0.336	S	S	.	.	H	α-helix	trans	-58.9	-44.9	178.8	-68.1	175.1	-174	-154.4	-2.3	112.4	L184 E254 C255 L260 Y261 L262	L184-R258 HydrophobicContact CD2-CB 4.41Å; L184-R258 HydrophobicContact CD2-CG 4.49Å; E254-R258 WeakPolarHBondContact O-CG 3.24Å; E254-R258 PolarHBondContact O-N 2.95Å; C255-R258 PolarHBondContact O-N 3.1Å; R258-L260 VanDerWaalsContact C-N 3.32Å; R258-L260 PolarHBondContact O-N 3.44Å; R258-Y261 PolarHBondContact O-N 2.54Å; R258-L262 PolarHBondContact O-N 3.29Å; R258-L262 VanDerWaalsContact O-N 3.1Å
259	R	82.3	Confident	79.9	Confident	5 Å²	5	66 Å²	66	2%	0.019	32%	0.322	C	S	.	.	H	α-helix	trans	-59.5	-42.6	175.6	-75	171.5	-176.3	-147.8	3.6	111.9	I186 I244 L245 C255 N256 K257 L262 L263	I186-R259 HydrophobicContact CD1-CG 4.01Å; I186-R259 HydrophobicContact CG1-CG 4.31Å; I186-R259 HydrophobicContact CG2-CG 3.81Å; I244-R259 HydrophobicContact CG2-CB 3.57Å; I244-R259 HydrophobicContact CG2-CG 3.58Å; I244-R259 PolarHBondContact O-NH1 3.26Å; L245-R259 HydrophobicContact CD1-CB 4.06Å; C255-R259 WeakPolarHBondContact O-CG 3.17Å; C255-R259 PolarHBondContact O-N 3.04Å; C255-R259 VanDerWaalsContact O-N 3.09Å; C255-R259 PolarHBondContact SG-NE 3.2Å; C255-R259 VanDerWaalsContact SG-NE 3.36Å; N256-R259 PolarHBondContact O-N 3.49Å; K257-R259 PolarHBondContact O-N 3.23Å; R259-L262 PolarHBondContact O-N 3.1Å; R259-L263 WeakPolarHBondContact O-CB 3.39Å; R259-L263 PolarHBondContact O-N 3.12Å; R259-L263 VanDerWaalsContact O-N 3.1Å
260	L	85	Confident	81.4	Confident	91 Å²	91	56.7 Å²	56.7	48%	0.476	28%	0.278	S	S	.	.	H	α-helix	trans	-66.4	-41.3	177.3	-174.8	66.7	0	0	0	112.3	N256 K257 R258 L263 L264	N256-L260 WeakPolarHBondContact O-CB 3.34Å; N256-L260 PolarHBondContact O-N 3.17Å; K257-L260 WeakPolarHBondContact O-CB 3.32Å; K257-L260 PolarHBondContact O-N 3.39Å; K257-L260 VanDerWaalsContact O-N 3.17Å; R258-L260 VanDerWaalsContact C-N 3.32Å; R258-L260 PolarHBondContact O-N 3.44Å; L260-L263 PolarHBondContact O-N 2.79Å; L260-L264 WeakPolarHBondContact O-CB 3.49Å; L260-L264 PolarHBondContact O-N 3.37Å
261	Y	86.5	Confident	82.8	Confident	166 Å²	166	57.6 Å²	57.6	65%	0.651	28%	0.282	S	S	*	.	H	α-helix	trans	-61.4	-43.4	175.9	-72.9	-60	0	0	0	112.2	K257 R258 L263 L264 L265	K257-Y261 HydrophobicContact CB-CD2 4.49Å; K257-Y261 HydrophobicContact CB-CE2 4.13Å; K257-Y261 WeakPolarHBondContact O-CD2 3.31Å; K257-Y261 PolarHBondContact O-N 3.33Å; R258-Y261 PolarHBondContact O-N 2.54Å; Y261-L263 VanDerWaalsContact C-N 3.35Å; Y261-L263 PolarHBondContact O-N 3.2Å; Y261-L264 PolarHBondContact O-N 3.03Å; Y261-L265 WeakPolarHBondContact O-CB 3.45Å; Y261-L265 PolarHBondContact O-N 2.95Å
262	L	87	Confident	84.1	Confident	9 Å²	9	60.8 Å²	60.8	5%	0.047	30%	0.301	C	S	.	.	H	α-helix	trans	-60.6	-45.3	175.2	177.6	146.2	0	0	0	111.5	A180 M181 L184 I186 I244 R258 R259 L264 L265 I266	A180-L262 HydrophobicContact CB-CD1 3.75Å; M181-L262 HydrophobicContact CB-CD1 4.41Å; M181-L262 HydrophobicContact CG-CD1 3.63Å; L184-L262 HydrophobicContact CD1-CB 3.87Å; L184-L262 HydrophobicContact CD1-CD1 3.92Å; I186-L262 HydrophobicContact CD1-CB 4.48Å; I186-L262 HydrophobicContact CD1-CD1 3.98Å; I244-L262 HydrophobicContact CD1-CD2 4.43Å; R258-L262 PolarHBondContact O-N 3.29Å; R258-L262 VanDerWaalsContact O-N 3.1Å; R259-L262 PolarHBondContact O-N 3.1Å; L262-L264 VanDerWaalsContact C-N 3.35Å; L262-L264 PolarHBondContact O-N 2.69Å; L262-L265 WeakPolarHBondContact O-CB 3.45Å; L262-L265 PolarHBondContact O-N 2.88Å; L262-I266 HydrophobicContact CD2-CD1 3.49Å; L262-I266 VanDerWaalsContact CD2-CD1 3.49Å; L262-I266 HydrophobicContact CD2-CG1 4.35Å; L262-I266 HydrophobicContact CG-CD1 4.19Å; L262-I266 WeakPolarHBondContact O-CG1 3.13Å; L262-I266 PolarHBondContact O-N 3.11Å
263	L	87.5	Confident	85.2	Confident	3 Å²	3	58.4 Å²	58.4	2%	0.016	28%	0.284	C	S	.	.	H	α-helix	trans	-62.7	-42.3	178.9	177.2	161	0	0	0	111.6	I237 L240 K241 I244 R259 L260 Y261 L265 I266 A267	I237-L263 HydrophobicContact CB-CD2 3.95Å; I237-L263 HydrophobicContact CG1-CD2 3.58Å; I237-L263 HydrophobicContact CG2-CD2 4Å; L240-L263 HydrophobicContact CB-CD1 3.77Å; L240-L263 HydrophobicContact CB-CG 4.21Å; K241-L263 HydrophobicContact CB-CD1 3.87Å; I244-L263 HydrophobicContact CD1-CB 4.44Å; I244-L263 HydrophobicContact CD1-CD1 4.38Å; R259-L263 WeakPolarHBondContact O-CB 3.39Å; R259-L263 PolarHBondContact O-N 3.12Å; R259-L263 VanDerWaalsContact O-N 3.1Å; L260-L263 PolarHBondContact O-N 2.79Å; Y261-L263 VanDerWaalsContact C-N 3.35Å; Y261-L263 PolarHBondContact O-N 3.2Å; L263-L265 VanDerWaalsContact C-N 3.34Å; L263-I266 PolarHBondContact O-N 3.17Å; L263-A267 WeakPolarHBondContact O-CB 2.78Å; L263-A267 PolarHBondContact O-N 3.05Å
264	L	89.4	Confident	86.3	Confident	100 Å²	100	54.8 Å²	54.8	52%	0.524	26%	0.258	S	S	.	.	H	α-helix	trans	-62.5	-42.8	175.8	-169.4	161.3	0	0	0	110.8	L260 Y261 L262 A267 F268	L260-L264 WeakPolarHBondContact O-CB 3.49Å; L260-L264 PolarHBondContact O-N 3.37Å; Y261-L264 PolarHBondContact O-N 3.03Å; L262-L264 VanDerWaalsContact C-N 3.35Å; L262-L264 PolarHBondContact O-N 2.69Å; L264-A267 PolarHBondContact O-N 3.37Å; L264-F268 HydrophobicContact CD2-CB 4.37Å; L264-F268 VanDerWaalsContact O-CB 3.28Å; L264-F268 WeakPolarHBondContact O-CB 3.28Å; L264-F268 PolarHBondContact O-N 3.24Å
265	L	89.5	Confident	87.3	Confident	89 Å²	89	54.4 Å²	54.4	47%	0.466	25%	0.253	S	S	.	.	H	α-helix	trans	-60.1	-47.2	176.9	-176	150.3	0	0	0	111.8	Y261 L262 L263 A267 F268 I269	Y261-L265 WeakPolarHBondContact O-CB 3.45Å; Y261-L265 PolarHBondContact O-N 2.95Å; L262-L265 WeakPolarHBondContact O-CB 3.45Å; L262-L265 PolarHBondContact O-N 2.88Å; L263-L265 VanDerWaalsContact C-N 3.34Å; L265-A267 VanDerWaalsContact C-N 3.31Å; L265-A267 PolarHBondContact O-N 3.02Å; L265-F268 PolarHBondContact O-N 2.93Å; L265-I269 PolarHBondContact O-N 3.46Å
266	I	90	Very high	88.3	Confident	14 Å²	14	58.8 Å²	58.8	7%	0.072	27%	0.269	C	S	.	.	H	α-helix	trans	-63.2	-37.7	176.5	-66.6	174.9	0	0	0	111.3	L240 L262 L263 I269 Q270	L240-I266 HydrophobicContact CD1-CG2 4.24Å; L262-I266 HydrophobicContact CD2-CD1 3.49Å; L262-I266 VanDerWaalsContact CD2-CD1 3.49Å; L262-I266 HydrophobicContact CD2-CG1 4.35Å; L262-I266 HydrophobicContact CG-CD1 4.19Å; L262-I266 WeakPolarHBondContact O-CG1 3.13Å; L262-I266 PolarHBondContact O-N 3.11Å; L263-I266 PolarHBondContact O-N 3.17Å; I266-I269 WeakPolarHBondContact O-CG2 2.87Å; I266-Q270 WeakPolarHBondContact O-CG 2.89Å; I266-Q270 PolarHBondContact O-NE2 3.02Å; I266-Q270 VanDerWaalsContact O-NE2 3.12Å
267	A	90.6	Very high	88.9	Confident	4 Å²	4	57.8 Å²	57.8	3%	0.033	26%	0.263	C	S	.	.	H	α-helix	trans	-71.3	-38.1	177.6	0	0	0	0	0	112.2	A233 I237 L263 L264 L265 Q270 P271	A233-A267 HydrophobicContact CB-CB 4.44Å; I237-A267 HydrophobicContact CD1-CB 4.06Å; I237-A267 HydrophobicContact CG1-CB 3.74Å; L263-A267 WeakPolarHBondContact O-CB 2.78Å; L263-A267 PolarHBondContact O-N 3.05Å; L264-A267 PolarHBondContact O-N 3.37Å; L265-A267 VanDerWaalsContact C-N 3.31Å; L265-A267 PolarHBondContact O-N 3.02Å; A267-Q270 PolarHBondContact O-N 2.88Å; A267-P271 WeakPolarHBondContact O-CD 3.27Å
268	F	89.6	Confident	89.4	Confident	140 Å²	140	53.4 Å²	53.4	61%	0.614	24%	0.244	S	C	*	.	H	α-helix	trans	-75.7	-26.7	-177.8	-172.4	-98.4	0	0	0	113.3	L264 L265 Q270 P271 L272	L264-F268 HydrophobicContact CD2-CB 4.37Å; L264-F268 VanDerWaalsContact O-CB 3.28Å; L264-F268 WeakPolarHBondContact O-CB 3.28Å; L264-F268 PolarHBondContact O-N 3.24Å; L265-F268 PolarHBondContact O-N 2.93Å; F268-Q270 VanDerWaalsContact C-N 3.28Å; F268-Q270 PolarHBondContact O-N 2.89Å; F268-P271 WeakPolarHBondContact O-CD 3.43Å; F268-L272 HydrophobicContact CD1-CD1 4.37Å; F268-L272 HydrophobicContact CE1-CD1 4.01Å
269	I	91	Very high	89.9	Confident	38 Å²	38	52.7 Å²	52.7	20%	0.195	24%	0.242	C	C	.	.	H	α-helix	trans	-70.9	-26.1	175.5	-149.5	168.9	0	0	0	111.6	E173 L176 L265 I266 L272 M273	E173-I269 HydrophobicContact CG-CG2 4.41Å; L176-I269 HydrophobicContact CD2-CD1 4.15Å; L265-I269 PolarHBondContact O-N 3.46Å; I266-I269 WeakPolarHBondContact O-CG2 2.87Å; I269-L272 PolarHBondContact O-N 3.15Å; I269-M273 HydrophobicContact CG1-CG 4.09Å; I269-M273 WeakPolarHBondContact O-CB 3.19Å; I269-M273 VanDerWaalsContact O-CG 3.26Å; I269-M273 WeakPolarHBondContact O-CG 3.36Å; I269-M273 PolarHBondContact O-N 3.05Å
270	Q	92.3	Very high	90.1	Very high	0 Å²	0	57.2 Å²	57.2	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-60.5	-50.6	-175.2	-55.5	-58.3	-32.9	0	0	114.4	E173 L232 L236 I266 A267 F268 L272 M273 M274	E173-Q270 PolarHBondContact OE1-NE2 2.88Å; L232-Q270 HydrophobicContact CD2-CB 3.88Å; L232-Q270 HydrophobicContact CD2-CG 4.11Å; L236-Q270 HydrophobicContact CD1-CG 3.37Å; I266-Q270 WeakPolarHBondContact O-CG 2.89Å; I266-Q270 PolarHBondContact O-NE2 3.02Å; I266-Q270 VanDerWaalsContact O-NE2 3.12Å; A267-Q270 PolarHBondContact O-N 2.88Å; F268-Q270 VanDerWaalsContact C-N 3.28Å; F268-Q270 PolarHBondContact O-N 2.89Å; Q270-L272 VanDerWaalsContact C-N 3.27Å; Q270-L272 PolarHBondContact O-N 3.48Å; Q270-M273 PolarHBondContact O-N 3.17Å; Q270-M274 WeakPolarHBondContact O-CB 3.41Å; Q270-M274 VanDerWaalsContact O-CG 3.32Å; Q270-M274 WeakPolarHBondContact O-CG 3.48Å; Q270-M274 PolarHBondContact O-N 2.87Å
271	P	90.5	Very high	90.2	Very high	41 Å²	41	52.9 Å²	52.9	27%	0.266	24%	0.236	S	C	.	.	H	α-helix	trans	-62	-37.6	-179	-23.9	36.6	0	0	0	112.2	A267 F268 M274 W275	A267-P271 WeakPolarHBondContact O-CD 3.27Å; F268-P271 WeakPolarHBondContact O-CD 3.43Å; P271-M274 PolarHBondContact O-N 2.85Å; P271-W275 WeakPolarHBondContact O-CB 3.36Å; P271-W275 PolarHBondContact O-N 2.9Å
272	L	91.8	Very high	90.2	Very high	94 Å²	94	45.9 Å²	45.9	49%	0.492	21%	0.209	S	C	.	.	H	α-helix	trans	-63.7	-46.3	176.7	-66.5	174.9	0	0	0	110.9	F268 I269 Q270 W275 W276	F268-L272 HydrophobicContact CD1-CD1 4.37Å; F268-L272 HydrophobicContact CE1-CD1 4.01Å; I269-L272 PolarHBondContact O-N 3.15Å; Q270-L272 VanDerWaalsContact C-N 3.27Å; Q270-L272 PolarHBondContact O-N 3.48Å; L272-W275 PolarHBondContact O-N 3.38Å; L272-W276 WeakPolarHBondContact O-CB 3.38Å; L272-W276 PolarHBondContact O-N 2.87Å
273	M	90.1	Very high	89.9	Confident	15 Å²	15	51.2 Å²	51.2	7%	0.074	24%	0.238	C	C	.	.	H	α-helix	trans	-65.7	-42.1	178.2	-72.1	-51.9	-52.7	0	0	112.5	W169 I269 Q270 W276 L277	W169-M273 HydrophobicContact CB-CE 3.48Å; W169-M273 VanDerWaalsContact CB-CE 3.48Å; W169-M273 HydrophobicContact CD2-CE 3.43Å; W169-M273 VanDerWaalsContact CD2-CE 3.43Å; W169-M273 HydrophobicContact CD2-SD 4.3Å; W169-M273 HydrophobicContact CE3-CE 3.48Å; W169-M273 VanDerWaalsContact CE3-CE 3.48Å; W169-M273 HydrophobicContact CE3-SD 3.85Å; W169-M273 HydrophobicContact CG-CE 3.44Å; W169-M273 VanDerWaalsContact CG-CE 3.44Å; W169-M273 HydrophobicContact CZ3-CE 4.33Å; W169-M273 HydrophobicContact CZ3-SD 4.17Å; I269-M273 HydrophobicContact CG1-CG 4.09Å; I269-M273 WeakPolarHBondContact O-CB 3.19Å; I269-M273 VanDerWaalsContact O-CG 3.26Å; I269-M273 WeakPolarHBondContact O-CG 3.36Å; I269-M273 PolarHBondContact O-N 3.05Å; Q270-M273 PolarHBondContact O-N 3.17Å; M273-W276 PolarHBondContact O-N 3.17Å; M273-L277 HydrophobicContact CE-CD1 4.3Å; M273-L277 WeakPolarHBondContact O-CB 3.42Å; M273-L277 WeakPolarHBondContact O-CG 3.5Å; M273-L277 PolarHBondContact O-N 2.98Å
274	M	93.3	Very high	90	Very high	0 Å²	0	53.7 Å²	53.7	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-58	-55.4	174.2	-78	175.4	43.6	0	0	110.6	K202 M206 L225 T228 S229 L232 Q270 P271 W276 L277 T278	K202-M274 HydrophobicContact CB-CG 4.35Å; M206-M274 HydrophobicContact CE-CB 4.36Å; M206-M274 HydrophobicContact CE-CG 3.88Å; M206-M274 HydrophobicContact CG-CG 4.13Å; L225-M274 HydrophobicContact CD1-CB 4.15Å; L225-M274 HydrophobicContact CD1-CE 4.01Å; T228-M274 WeakPolarHBondContact OG1-CE 3.44Å; S229-M274 VanDerWaalsContact OG-CE 3.31Å; S229-M274 WeakPolarHBondContact OG-CE 3.25Å; L232-M274 HydrophobicContact CD2-SD 3.56Å; L232-M274 VanDerWaalsContact CD2-SD 3.56Å; Q270-M274 WeakPolarHBondContact O-CB 3.41Å; Q270-M274 VanDerWaalsContact O-CG 3.32Å; Q270-M274 WeakPolarHBondContact O-CG 3.48Å; Q270-M274 PolarHBondContact O-N 2.87Å; P271-M274 PolarHBondContact O-N 2.85Å; M274-W276 VanDerWaalsContact C-N 3.3Å; M274-W276 PolarHBondContact O-N 3.07Å; M274-L277 PolarHBondContact O-N 3.29Å; M274-T278 WeakPolarHBondContact O-CG2 3.4Å; M274-T278 PolarHBondContact O-N 3.2Å; M274-T278 PolarHBondContact O-OG1 3.05Å
275	W	93	Very high	90	Very high	98 Å²	98	51.2 Å²	51.2	37%	0.371	23%	0.234	S	C	.	.	H	α-helix	trans	-57.4	-42.8	178.7	174.2	75.3	0	0	0	112.2	L225 P271 L272 R279	L225-W275 HydrophobicContact CD2-CB 4.11Å; L225-W275 HydrophobicContact CD2-CG 4.31Å; P271-W275 WeakPolarHBondContact O-CB 3.36Å; P271-W275 PolarHBondContact O-N 2.9Å; L272-W275 PolarHBondContact O-N 3.38Å; W275-R279 WeakPolarHBondContact O-CB 3.25Å; W275-R279 PolarHBondContact O-N 3.39Å
276	W	92.7	Very high	90	Very high	97 Å²	97	49.1 Å²	49.1	37%	0.367	22%	0.221	S	C	.	.	H	α-helix	trans	-62.6	-47.9	-179.8	-177.7	-95.8	0	0	0	112.6	W169 L272 M273 M274	W169-W276 AromaticContact NE1-CD1 3.91Å; W169-W276 AromaticContact NE1-NE1 3.67Å; L272-W276 WeakPolarHBondContact O-CB 3.38Å; L272-W276 PolarHBondContact O-N 2.87Å; M273-W276 PolarHBondContact O-N 3.17Å; M274-W276 VanDerWaalsContact C-N 3.3Å; M274-W276 PolarHBondContact O-N 3.07Å
277	L	91.9	Very high	90.1	Very high	0 Å²	0	51.2 Å²	51.2	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-72.8	-40.5	-177.3	-74.6	167.3	0	0	0	112.2	Y140 M206 M273 M274	Y140-L277 PolarHBondContact OH-O 3.28Å; M206-L277 HydrophobicContact CE-CB 4.09Å; M206-L277 HydrophobicContact CE-CD1 3.48Å; M206-L277 VanDerWaalsContact CE-CD1 3.48Å; M206-L277 HydrophobicContact CE-CG 4.4Å; M206-L277 HydrophobicContact SD-CB 4.4Å; M206-L277 HydrophobicContact SD-CD1 4.3Å; M273-L277 HydrophobicContact CE-CD1 4.3Å; M273-L277 WeakPolarHBondContact O-CB 3.42Å; M273-L277 WeakPolarHBondContact O-CG 3.5Å; M273-L277 PolarHBondContact O-N 2.98Å; M274-L277 PolarHBondContact O-N 3.29Å
278	T	91.8	Very high	90	Very high	0 Å²	0	54.1 Å²	54.1	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-77.1	-30.5	-178.9	56.5	0	0	0	0	112.8	M206 V209 Y221 M274 R280 V281 I282	M206-T278 HydrophobicContact CB-CG2 3.92Å; M206-T278 HydrophobicContact CG-CG2 3.83Å; V209-T278 HydrophobicContact CG1-CG2 4.43Å; Y221-T278 PolarHBondContact OH-OG1 3Å; M274-T278 WeakPolarHBondContact O-CG2 3.4Å; M274-T278 PolarHBondContact O-N 3.2Å; M274-T278 PolarHBondContact O-OG1 3.05Å; T278-R280 PolarHBondContact O-N 3.38Å; T278-V281 PolarHBondContact O-N 3.41Å; T278-V281 VanDerWaalsContact O-N 3.09Å; T278-I282 PolarHBondContact O-N 2.95Å
279	R	91.2	Very high	90	Very high	103 Å²	103	48.4 Å²	48.4	39%	0.389	22%	0.218	S	C	.	.	H	α-helix	trans	-55.9	-37.8	175.7	174.3	-179.6	176.3	-165.4	-2.1	112.4	W275 V281 I282 L283	W275-R279 WeakPolarHBondContact O-CB 3.25Å; W275-R279 PolarHBondContact O-N 3.39Å; R279-V281 VanDerWaalsContact C-N 3.27Å; R279-V281 PolarHBondContact O-N 3.42Å; R279-I282 PolarHBondContact O-N 3.5Å; R279-L283 HydrophobicContact CG-CD1 3.48Å; R279-L283 VanDerWaalsContact CG-CD1 3.48Å; R279-L283 HydrophobicContact CG-CG 4.07Å; R279-L283 PolarHBondContact O-N 3.45Å; R279-L283 VanDerWaalsContact O-N 3.08Å
280	R	86.9	Confident	90	Very high	99 Å²	99	49.1 Å²	49.1	37%	0.374	22%	0.219	S	C	.	.	H	α-helix	trans	-67.1	-25.5	179.8	-69.2	176.3	175.6	-124.4	7.6	113.8	E165 T278	E165-R280 IonicContact OE1-CZ 3.22Å; E165-R280 VanDerWaalsContact OE1-CZ 3.22Å; E165-R280 IonicContact OE1-NH1 2.58Å; E165-R280 PolarHBondContact OE1-NH1 3.15Å; E165-R280 IonicContact OE1-NH2 3.43Å; E165-R280 PolarHBondContact OE1-NH2 3.41Å; E165-R280 WeakPolarHBondContact OE2-CD 3.38Å; E165-R280 IonicContact OE2-CZ 3.18Å; E165-R280 IonicContact OE2-NE 2.65Å; E165-R280 IonicContact OE2-NH1 2.68Å; E165-R280 PolarHBondContact OE2-NH1 3.35Å; T278-R280 PolarHBondContact O-N 3.38Å
281	V	88.6	Confident	89.8	Confident	0 Å²	0	52.9 Å²	52.9	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-80.4	-24.6	178.1	-177.8	0	0	0	0	110.9	Y140 I147 F148 L162 L210 T278 R279	Y140-V281 HydrophobicContact CE2-CG2 4.49Å; I147-V281 HydrophobicContact CB-CG1 4.21Å; I147-V281 HydrophobicContact CD1-CG1 4Å; I147-V281 HydrophobicContact CG2-CG1 4.11Å; F148-V281 HydrophobicContact CE1-CG1 4.31Å; F148-V281 HydrophobicContact CZ-CG1 4.38Å; F148-V281 HydrophobicContact CZ-CG2 4.46Å; L162-V281 HydrophobicContact CD1-CG2 3.99Å; L162-V281 HydrophobicContact CD2-CG2 4.14Å; L210-V281 HydrophobicContact CD1-CG1 4.4Å; L210-V281 HydrophobicContact CD2-CB 4.1Å; L210-V281 HydrophobicContact CD2-CG1 3.9Å; T278-V281 PolarHBondContact O-N 3.41Å; T278-V281 VanDerWaalsContact O-N 3.09Å; R279-V281 VanDerWaalsContact C-N 3.27Å; R279-V281 PolarHBondContact O-N 3.42Å
282	I	86.2	Confident	89.7	Confident	19 Å²	19	53.9 Å²	53.9	10%	0.097	23%	0.234	C	C	.	.	H	α-helix	trans	-99.3	-32.2	-170.6	-66	168.7	0	0	0	112.9	L210 Y213 Y221 T278 R279	L210-I282 HydrophobicContact CD2-CD1 4.49Å; L210-I282 HydrophobicContact CD2-CG1 4.48Å; Y213-I282 HydrophobicContact CD1-CG1 4.06Å; Y213-I282 HydrophobicContact CD2-CD1 4.29Å; Y213-I282 HydrophobicContact CD2-CG1 4.32Å; Y213-I282 HydrophobicContact CD2-CG2 4.17Å; Y213-I282 HydrophobicContact CE1-CG1 4.19Å; Y213-I282 HydrophobicContact CE2-CG1 4.46Å; Y213-I282 HydrophobicContact CE2-CG2 3.71Å; Y213-I282 HydrophobicContact CG-CD1 4.17Å; Y213-I282 HydrophobicContact CG-CG1 4.13Å; Y221-I282 HydrophobicContact CD1-CD1 4.03Å; Y221-I282 HydrophobicContact CD2-CD1 2.98Å; Y221-I282 HydrophobicContact CD2-CG1 4.47Å; Y221-I282 HydrophobicContact CE1-CD1 4.06Å; Y221-I282 HydrophobicContact CE2-CD1 3.04Å; Y221-I282 HydrophobicContact CG-CD1 3.49Å; Y221-I282 VanDerWaalsContact CG-CD1 3.49Å; T278-I282 PolarHBondContact O-N 2.95Å; R279-I282 PolarHBondContact O-N 3.5Å
283	L	79.6	Confident	89.6	Confident	122 Å²	122	50.3 Å²	50.3	64%	0.639	21%	0.21	S	C	*	.			trans	-88.3	0	177.8	-65.3	-179.3	0	0	0	111.1	R153 R279	R153-L283 PolarHBondContact NH1-O 3.38Å; R279-L283 HydrophobicContact CG-CD1 3.48Å; R279-L283 VanDerWaalsContact CG-CD1 3.48Å; R279-L283 HydrophobicContact CG-CG 4.07Å; R279-L283 PolarHBondContact O-N 3.45Å; R279-L283 VanDerWaalsContact O-N 3.08Å

Retrieved 283 of 283 residues in 185.7 ms (Link to these results)

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