A0A3Q0KJT7_SCHMA Loading...

N-methyl-D-aspartate receptor-associated protein, putative

AlphaFold DB , UniProt , Accession A0A3Q0KJT7, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 256 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	35.8	Very low	32.7	Very low	199 Å²	199	122.4 Å²	122.4	98%	0.98	66%	0.658	S	S	*	*				0	115.3	0	-98.6	175.8	179.1	0	0	106.2	H3	M1-H3 PolarHBondContact O-N 2.62Å
2	L	38.2	Very low	32.1	Very low	73 Å²	73	122.5 Å²	122.5	38%	0.382	67%	0.666	S	S	.	*	P	Polyproline II helix	trans	-65.1	120.8	167.9	-75.7	158	0	0	0	106.6	K4 I214 I221	L2-K4 PolarHBondContact O-N 3.3Å; L2-I214 HydrophobicContact CD2-CG2 4.32Å; L2-I221 HydrophobicContact CB-CB 4.18Å; L2-I221 HydrophobicContact CB-CD1 3.71Å; L2-I221 HydrophobicContact CB-CG1 3.89Å; L2-I221 HydrophobicContact CB-CG2 3.35Å; L2-I221 HydrophobicContact CD1-CD1 4.03Å; L2-I221 HydrophobicContact CD1-CG2 3.78Å; L2-I221 HydrophobicContact CD2-CG2 3.08Å; L2-I221 HydrophobicContact CG-CD1 4.38Å; L2-I221 HydrophobicContact CG-CG2 3.47Å; L2-I221 VanDerWaalsContact CG-CG2 3.47Å
3	H	40.2	Very low	31.8	Very low	91 Å²	91	128.1 Å²	128.1	42%	0.421	67%	0.674	S	S	.	*	P	Polyproline II helix	trans	-67.9	122	-178.4	-91.3	-83.6	0	0	0	108.9	M1 R224	M1-H3 PolarHBondContact O-N 2.62Å; H3-R224 PolarHBondContact CD2-NH2 2.67Å; H3-R224 PolarHBondContact NE2-NH2 3.06Å
4	K	34.5	Very low	31.4	Very low	141 Å²	141	132.4 Å²	132.4	61%	0.613	68%	0.684	S	S	*	*	P	Polyproline II helix	trans	-79.4	138.9	167.6	-139	178.1	-176.2	-172.3	0	108.3	L2 E220	L2-K4 PolarHBondContact O-N 3.3Å; K4-E220 WeakPolarHBondContact CA-O 3.42Å; K4-E220 WeakPolarHBondContact CE-OE1 3.36Å; K4-E220 IonicContact NZ-OE1 2.82Å
5	Y	38.7	Very low	31.2	Very low	69 Å²	69	136.5 Å²	136.5	27%	0.271	70%	0.698	S	S	.	*	P	Polyproline II helix	trans	-54.8	141.3	170.1	-97.6	-103	0	0	0	110.4	N7 I23 I25 R219 E220 Y222	Y5-N7 PolarHBondContact O-N 2.96Å; Y5-I23 PolarHBondContact OH-O 3.1Å; Y5-I25 HydrophobicContact CE2-CD1 4.25Å; Y5-I25 VanDerWaalsContact OH-CB 3.26Å; Y5-I25 WeakPolarHBondContact OH-CB 3.45Å; Y5-I25 WeakPolarHBondContact OH-CG1 3.43Å; Y5-I25 PolarHBondContact OH-N 3.15Å; Y5-R219 WeakPolarHBondContact CD2-O 3.23Å; Y5-R219 WeakPolarHBondContact CE2-O 3.47Å; Y5-E220 PolarHBondContact N-O 3.28Å; Y5-Y222 HydrophobicContact CE2-CD1 4.37Å; Y5-Y222 HydrophobicContact CE2-CE1 4.31Å
6	P	35	Very low	30.8	Very low	115 Å²	115	132.9 Å²	132.9	75%	0.747	71%	0.705	S	S	*	*			trans	-68.2	105.1	164.4	28.3	-28.4	0	0	0	107.5
7	N	29.4	Very low	30.6	Very low	134 Å²	134	132.9 Å²	132.9	72%	0.717	72%	0.717	S	S	*	*			trans	-65.6	136.4	160.9	-79	-14.4	0	0	0	107.8	Y5	Y5-N7 PolarHBondContact O-N 2.96Å
8	E	26.7	Very low	30.3	Very low	198 Å²	198	136.5 Å²	136.5	93%	0.925	73%	0.725	S	S	*	*			trans	103	103.7	173.4	-59.3	174.5	-172.7	0	0	115.8
9	G	27.3	Very low	30.1	Very low	73 Å²	73	141.7 Å²	141.7	75%	0.753	74%	0.735	S	S	*	*			trans	168	92.5	167.2	0	0	0	0	0	112.8
10	S	26.1	Very low	30	Very low	107 Å²	107	141.6 Å²	141.6	75%	0.748	74%	0.736	S	S	*	*			trans	-37.1	132.9	173.8	52.5	0	0	0	0	115	T12	S10-T12 PolarHBondContact O-N 2.94Å; S10-T12 VanDerWaalsContact O-N 3.08Å
11	H	28	Very low	30.2	Very low	146 Å²	146	143.8 Å²	143.8	68%	0.676	74%	0.742	S	S	*	*			trans	-56.9	108.1	167.9	-68.2	-94.3	0	0	0	111.7	Y13	H11-Y13 AromaticContact ND1-CE2 3.77Å
12	T	25.2	Very low	30	Very low	124 Å²	124	141.1 Å²	141.1	76%	0.761	73%	0.728	S	S	*	*			trans	-138.3	92.6	150.9	45.5	0	0	0	0	108.2	S10 K14	S10-T12 PolarHBondContact O-N 2.94Å; S10-T12 VanDerWaalsContact O-N 3.08Å; T12-K14 PolarHBondContact O-N 3.32Å
13	Y	29	Very low	29.8	Very low	195 Å²	195	139.8 Å²	139.8	77%	0.765	72%	0.721	S	S	*	*			trans	-78.3	99.5	171.2	-76.6	-80.5	0	0	0	109.3	H11	H11-Y13 AromaticContact ND1-CE2 3.77Å
14	K	25.1	Very low	29.5	Very low	189 Å²	189	140 Å²	140	82%	0.822	73%	0.728	S	S	*	*			trans	-116.2	121.5	161.2	-97.2	-177.4	175.2	178.6	0	108.7	T12	T12-K14 PolarHBondContact O-N 3.32Å
15	H	28.3	Very low	29.5	Very low	193 Å²	193	135.1 Å²	135.1	89%	0.894	71%	0.708	S	S	*	*	S	Bend	trans	39.6	113.8	158.9	-78.4	-75.9	0	0	0	119.7
16	G	26	Very low	29.1	Very low	79 Å²	79	135 Å²	135	81%	0.814	72%	0.716	S	S	*	*			trans	83.2	60.2	143.9	0	0	0	0	0	116.8
17	C	27.4	Very low	29.2	Very low	133 Å²	133	137.8 Å²	137.8	90%	0.899	72%	0.72	S	S	*	*			trans	-92.2	115.6	169.9	-86.7	0	0	0	0	112.2
18	K	24	Very low	29.2	Very low	198 Å²	198	136.7 Å²	136.7	86%	0.861	71%	0.714	S	S	*	*			trans	-48.1	140.4	161.8	-77	169.5	169.5	174	0	111	N20	K18-N20 PolarHBondContact O-N 3.06Å
19	Y	27.6	Very low	29.8	Very low	235 Å²	235	129.9 Å²	129.9	92%	0.922	69%	0.688	S	S	*	*			trans	-60	93.6	169	-72	-88.1	0	0	0	110.2
20	N	28.2	Very low	30.2	Very low	139 Å²	139	131.7 Å²	131.7	74%	0.743	68%	0.675	S	S	*	*			trans	-88.8	138.4	155.6	-93.3	-9.5	0	0	0	108.1	K18 Q22	K18-N20 PolarHBondContact O-N 3.06Å; N20-Q22 PolarHBondContact O-N 3.07Å
21	E	33.6	Very low	30.4	Very low	188 Å²	188	134.1 Å²	134.1	88%	0.879	68%	0.679	S	S	*	*	S	Bend	trans	-67.3	27.1	-173	-62.2	-178.7	134.6	0	0	115.2
22	Q	30.8	Very low	30.6	Very low	143 Å²	143	130.4 Å²	130.4	67%	0.668	67%	0.67	S	S	*	*			trans	-93.6	114.6	169.6	-73.3	178.7	-17	0	0	108	N20 V24	N20-Q22 PolarHBondContact O-N 3.07Å; Q22-V24 VanDerWaalsContact C-N 3.28Å; Q22-V24 PolarHBondContact O-N 3.06Å
23	I	35.9	Very low	31.3	Very low	46 Å²	46	128.5 Å²	128.5	24%	0.236	68%	0.675	C	S	.	*			trans	-63.3	94.9	172.8	-59.6	169.8	0	0	0	106.4	Y5 I25	Y5-I23 PolarHBondContact OH-O 3.1Å; I23-I25 HydrophobicContact CG2-CG1 4.14Å; I23-I25 PolarHBondContact O-N 3.24Å; I23-I25 VanDerWaalsContact O-N 3.13Å
24	V	31.9	Very low	31.9	Very low	96 Å²	96	127.1 Å²	127.1	58%	0.582	68%	0.677	S	S	*	*			trans	-69.1	102.9	165.5	179.9	0	0	0	0	105.6	Q22 C26	Q22-V24 VanDerWaalsContact C-N 3.28Å; Q22-V24 PolarHBondContact O-N 3.06Å; V24-C26 VanDerWaalsContact C-N 3.26Å; V24-C26 PolarHBondContact O-N 2.78Å
25	I	35.2	Very low	33.5	Very low	37 Å²	37	121 Å²	121	19%	0.19	65%	0.653	C	S	.	*			trans	-74.8	94.3	164.8	-58.9	159	0	0	0	103.9	Y5 I23 E27 G217 G218	Y5-I25 HydrophobicContact CE2-CD1 4.25Å; Y5-I25 VanDerWaalsContact OH-CB 3.26Å; Y5-I25 WeakPolarHBondContact OH-CB 3.45Å; Y5-I25 WeakPolarHBondContact OH-CG1 3.43Å; Y5-I25 PolarHBondContact OH-N 3.15Å; I23-I25 HydrophobicContact CG2-CG1 4.14Å; I23-I25 PolarHBondContact O-N 3.24Å; I23-I25 VanDerWaalsContact O-N 3.13Å; I25-E27 PolarHBondContact O-N 3.2Å; I25-G217 WeakPolarHBondContact CD1-O 3.35Å; I25-G218 WeakPolarHBondContact CD1-O 3.37Å
26	C	30.6	Very low	35.3	Very low	66 Å²	66	115.3 Å²	115.3	45%	0.446	63%	0.629	S	S	.	*			trans	-54.2	133	167	-67.2	0	0	0	0	107.8	V24 D28 S29	V24-C26 VanDerWaalsContact C-N 3.26Å; V24-C26 PolarHBondContact O-N 2.78Å; C26-D28 HydrophobicContact CB-CB 4.32Å; C26-D28 PolarHBondContact O-N 2.8Å; C26-S29 PolarHBondContact O-N 2.62Å
27	E	36.5	Very low	37.6	Very low	175 Å²	175	115.3 Å²	115.3	82%	0.818	62%	0.615	S	S	*	*	G	3₁₀ helix	trans	-52.2	-18.8	167.9	-80.6	178	136.7	0	0	112.1	I25	I25-E27 PolarHBondContact O-N 3.2Å
28	D	30.9	Very low	39.9	Very low	111 Å²	111	114.2 Å²	114.2	59%	0.594	59%	0.594	S	S	*	*	G	3₁₀ helix	trans	-82.4	1	175.5	-67.7	-33.3	0	0	0	116.1	C26 K30 L31 S32	C26-D28 HydrophobicContact CB-CB 4.32Å; C26-D28 PolarHBondContact O-N 2.8Å; D28-K30 PolarHBondContact O-N 3.18Å; D28-L31 PolarHBondContact O-N 3.29Å; D28-S32 PolarHBondContact O-N 3.39Å
29	S	38.4	Very low	42.6	Very low	55 Å²	55	105.6 Å²	105.6	39%	0.385	56%	0.557	S	S	.	*	G	3₁₀ helix	trans	-70.4	-1.4	-178.9	84.9	0	0	0	0	114.3	C26 S32	C26-S29 PolarHBondContact O-N 2.62Å; S29-S32 VanDerWaalsContact O-O 3.13Å
30	K	35.3	Very low	45.2	Very low	111 Å²	111	97.7 Å²	97.7	48%	0.483	53%	0.53	S	S	.	.	G	3₁₀ helix	trans	-89.9	-21.3	164.4	-82.6	-168	167.6	-167.8	0	113.1	D28 E157	D28-K30 PolarHBondContact O-N 3.18Å; K30-E157 IonicContact NZ-OE1 3.83Å; K30-E157 PolarHBondContact NZ-OE1 3.26Å
31	L	31.6	Very low	48	Very low	158 Å²	158	99.5 Å²	99.5	83%	0.827	53%	0.526	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.5	-25.7	178.9	-120.3	89.4	0	0	0	112.6	D28	D28-L31 PolarHBondContact O-N 3.29Å
32	S	31.3	Very low	50.5	Low	68 Å²	68	91.2 Å²	91.2	48%	0.476	49%	0.487	S	S	.	.	S	Bend	trans	-105.3	109.9	162.3	81.4	0	0	0	0	108.2	D28 S29 M34	D28-S32 PolarHBondContact O-N 3.39Å; S29-S32 VanDerWaalsContact O-O 3.13Å; S32-M34 PolarHBondContact O-N 3.33Å
33	G	39.2	Very low	53.2	Low	84 Å²	84	85.4 Å²	85.4	87%	0.866	46%	0.46	S	S	*	.			trans	-64.8	27.3	175.9	0	0	0	0	0	114.5
34	M	41.5	Very low	55.7	Low	165 Å²	165	88.3 Å²	88.3	81%	0.813	48%	0.476	S	S	*	.			trans	-107.9	98.5	179.7	-81.6	-173.8	138.2	0	0	109.8	S32 D36	S32-M34 PolarHBondContact O-N 3.33Å; M34-D36 PolarHBondContact O-N 3.23Å
35	I	58.7	Low	58.4	Low	62 Å²	62	88.8 Å²	88.8	32%	0.318	47%	0.47	S	S	.	.			trans	-54.6	131.3	164.1	-51.4	167.7	0	0	0	107.7	P37 R39 I40 Y216	I35-P37 WeakPolarHBondContact O-CD 3.4Å; I35-P37 VanDerWaalsContact O-N 3.07Å; I35-R39 HydrophobicContact CG2-CB 4.27Å; I35-I40 HydrophobicContact CB-CD1 3.84Å; I35-I40 HydrophobicContact CB-CG1 3.83Å; I35-I40 HydrophobicContact CD1-CD1 4.44Å; I35-I40 HydrophobicContact CD1-CG1 4.33Å; I35-I40 HydrophobicContact CG2-CD1 4.11Å; I35-I40 HydrophobicContact CG2-CG1 3.51Å; I35-Y216 HydrophobicContact CD1-CE2 3.74Å; I35-Y216 HydrophobicContact CG1-CE2 3.79Å; I35-Y216 WeakPolarHBondContact CG1-OH 3.32Å; I35-Y216 HydrophobicContact CG2-CE2 4.23Å
36	D	66.8	Low	61	Low	73 Å²	73	87 Å²	87	39%	0.39	46%	0.461	S	S	.	.			trans	-51.8	120.8	175.1	-179.8	-7	0	0	0	108.5	M34 K38 R39 I40	M34-D36 PolarHBondContact O-N 3.23Å; D36-K38 PolarHBondContact O-N 3.38Å; D36-K38 WeakPolarHBondContact OD1-CB 3.36Å; D36-K38 PolarHBondContact OD1-N 3.04Å; D36-R39 HydrophobicContact CB-CB 4.34Å; D36-R39 WeakPolarHBondContact O-CA 3.25Å; D36-R39 WeakPolarHBondContact O-CB 3.3Å; D36-R39 PolarHBondContact O-N 3.33Å; D36-I40 PolarHBondContact O-N 3.45Å; D36-I40 VanDerWaalsContact O-N 3.16Å
37	P	74.2	Confident	63.9	Low	79 Å²	79	85.9 Å²	85.9	51%	0.513	45%	0.449	S	S	.	.	H	α-helix	trans	-57.1	-21.7	-178	20	-32.4	0	0	0	112.7	I35 R41	I35-P37 WeakPolarHBondContact O-CD 3.4Å; I35-P37 VanDerWaalsContact O-N 3.07Å; P37-R41 PolarHBondContact O-N 3.03Å
38	K	76.1	Confident	66.5	Low	109 Å²	109	83.4 Å²	83.4	47%	0.474	44%	0.44	S	S	.	.	H	α-helix	trans	-72.9	-31.9	173	-61.5	-179.4	-175.3	172	0	112.5	D36 F42 R225	D36-K38 PolarHBondContact O-N 3.38Å; D36-K38 WeakPolarHBondContact OD1-CB 3.36Å; D36-K38 PolarHBondContact OD1-N 3.04Å; K38-F42 PolarHBondContact O-N 3.02Å; K38-R225 VanDerWaalsContact CB-NH2 3.3Å
39	R	80.8	Confident	69.2	Low	18 Å²	18	79.5 Å²	79.5	7%	0.068	42%	0.421	C	S	.	.	H	α-helix	trans	-74.9	-40.8	175.2	-161.7	80.5	-170.7	-177.5	5.4	111.5	I35 D36 R41 F42 I43 I214 L215 Y216 Y223	I35-R39 HydrophobicContact CG2-CB 4.27Å; D36-R39 HydrophobicContact CB-CB 4.34Å; D36-R39 WeakPolarHBondContact O-CA 3.25Å; D36-R39 WeakPolarHBondContact O-CB 3.3Å; D36-R39 PolarHBondContact O-N 3.33Å; R39-R41 VanDerWaalsContact C-N 3.28Å; R39-R41 PolarHBondContact O-N 3.22Å; R39-F42 WeakPolarHBondContact O-CB 3.48Å; R39-F42 PolarHBondContact O-N 3.3Å; R39-I43 HydrophobicContact CG-CD1 4.28Å; R39-I43 WeakPolarHBondContact O-CG1 3.41Å; R39-I43 PolarHBondContact O-N 2.93Å; R39-I214 PolarHBondContact NH2-O 3.36Å; R39-L215 VanDerWaalsContact CZ-O 3.23Å; R39-L215 PolarHBondContact NE-O 3.23Å; R39-L215 PolarHBondContact NH2-O 3.12Å; R39-Y216 WeakPolarHBondContact CG-O 3.41Å; R39-Y216 PolarHBondContact NE-O 3.44Å; R39-Y223 PolarHBondContact NH1-O 3.14Å
40	I	82.7	Confident	71.6	Confident	69 Å²	69	77.1 Å²	77.1	35%	0.354	40%	0.403	S	S	.	.	H	α-helix	trans	-55.8	-47.2	172.4	-65.4	169.1	0	0	0	110.1	I35 D36 F42 I43 L44	I35-I40 HydrophobicContact CB-CD1 3.84Å; I35-I40 HydrophobicContact CB-CG1 3.83Å; I35-I40 HydrophobicContact CD1-CD1 4.44Å; I35-I40 HydrophobicContact CD1-CG1 4.33Å; I35-I40 HydrophobicContact CG2-CD1 4.11Å; I35-I40 HydrophobicContact CG2-CG1 3.51Å; D36-I40 PolarHBondContact O-N 3.45Å; D36-I40 VanDerWaalsContact O-N 3.16Å; I40-F42 VanDerWaalsContact C-N 3.29Å; I40-F42 PolarHBondContact O-N 3.18Å; I40-I43 PolarHBondContact O-N 3.46Å; I40-L44 HydrophobicContact CG2-CD1 3.71Å; I40-L44 HydrophobicContact CG2-CG 4.19Å; I40-L44 WeakPolarHBondContact O-CB 3.33Å; I40-L44 WeakPolarHBondContact O-CG 3.22Å; I40-L44 PolarHBondContact O-N 3.25Å
41	R	85.1	Confident	74.2	Confident	176 Å²	176	76.9 Å²	76.9	66%	0.664	41%	0.406	S	S	*	.	H	α-helix	trans	-60	-37.8	176.5	-85.6	-172	-99.5	-176.5	-12	113.2	P37 R39 K45	P37-R41 PolarHBondContact O-N 3.03Å; R39-R41 VanDerWaalsContact C-N 3.28Å; R39-R41 PolarHBondContact O-N 3.22Å; R41-K45 WeakPolarHBondContact O-CB 3.45Å; R41-K45 PolarHBondContact O-N 3.06Å
42	F	86.5	Confident	77	Confident	15 Å²	15	75.4 Å²	75.4	7%	0.066	40%	0.399	C	S	.	.	H	α-helix	trans	-64.1	-49.6	175.5	176.5	-92.9	0	0	0	111.6	K38 R39 I40 L44 K45 V46 L215 Y223 F228 A231	K38-F42 PolarHBondContact O-N 3.02Å; R39-F42 WeakPolarHBondContact O-CB 3.48Å; R39-F42 PolarHBondContact O-N 3.3Å; I40-F42 VanDerWaalsContact C-N 3.29Å; I40-F42 PolarHBondContact O-N 3.18Å; F42-L44 PolarHBondContact O-N 2.88Å; F42-K45 WeakPolarHBondContact O-CB 3.17Å; F42-K45 PolarHBondContact O-N 3.35Å; F42-V46 HydrophobicContact CE1-CG2 4.14Å; F42-V46 HydrophobicContact CZ-CG2 4.28Å; F42-V46 PolarHBondContact O-N 3.36Å; F42-L215 HydrophobicContact CE1-CD2 3.87Å; F42-Y223 HydrophobicContact CZ-CG 4.46Å; F42-F228 HydrophobicContact CD2-CB 4.22Å; F42-F228 HydrophobicContact CE2-CB 3.62Å; F42-F228 HydrophobicContact CZ-CB 4.4Å; F42-A231 HydrophobicContact CE1-CB 4.36Å; F42-A231 HydrophobicContact CZ-CB 3.93Å
43	I	87.3	Confident	79.6	Confident	20 Å²	20	72.5 Å²	72.5	10%	0.103	38%	0.377	C	S	.	.	H	α-helix	trans	-60.6	-48.1	178.5	-64.6	165.8	0	0	0	110.4	R39 I40 K45 V46 F47 F150 Y216	R39-I43 HydrophobicContact CG-CD1 4.28Å; R39-I43 WeakPolarHBondContact O-CG1 3.41Å; R39-I43 PolarHBondContact O-N 2.93Å; I40-I43 PolarHBondContact O-N 3.46Å; I43-K45 VanDerWaalsContact C-N 3.26Å; I43-K45 PolarHBondContact O-N 3.28Å; I43-V46 WeakPolarHBondContact O-CB 3.29Å; I43-V46 PolarHBondContact O-N 2.9Å; I43-V46 VanDerWaalsContact O-N 3.14Å; I43-F47 HydrophobicContact CG2-CD2 3.73Å; I43-F47 HydrophobicContact CG2-CE2 3.85Å; I43-F47 WeakPolarHBondContact O-CD2 3.46Å; I43-F47 PolarHBondContact O-N 3.31Å; I43-F150 HydrophobicContact CD1-CZ 4.38Å; I43-F150 HydrophobicContact CG2-CE1 4.02Å; I43-F150 HydrophobicContact CG2-CZ 3.63Å; I43-Y216 HydrophobicContact CD1-CD2 4.46Å
44	L	89.4	Confident	81.9	Confident	108 Å²	108	69 Å²	69	57%	0.565	34%	0.339	S	S	*	.	H	α-helix	trans	-57.3	-40.4	176.3	-77.7	171	0	0	0	112	I40 F42 F47 L48	I40-L44 HydrophobicContact CG2-CD1 3.71Å; I40-L44 HydrophobicContact CG2-CG 4.19Å; I40-L44 WeakPolarHBondContact O-CB 3.33Å; I40-L44 WeakPolarHBondContact O-CG 3.22Å; I40-L44 PolarHBondContact O-N 3.25Å; F42-L44 PolarHBondContact O-N 2.88Å; L44-F47 PolarHBondContact O-N 2.75Å; L44-L48 WeakPolarHBondContact O-CB 3.36Å; L44-L48 PolarHBondContact O-N 3.23Å
45	K	89.2	Confident	84.1	Confident	106 Å²	106	67.8 Å²	67.8	46%	0.461	33%	0.33	S	S	.	.	H	α-helix	trans	-64.6	-41.6	177.7	-167.6	-179.6	-179.8	-169.7	0	111.9	R41 F42 I43 T49 F228	R41-K45 WeakPolarHBondContact O-CB 3.45Å; R41-K45 PolarHBondContact O-N 3.06Å; F42-K45 WeakPolarHBondContact O-CB 3.17Å; F42-K45 PolarHBondContact O-N 3.35Å; I43-K45 VanDerWaalsContact C-N 3.26Å; I43-K45 PolarHBondContact O-N 3.28Å; K45-T49 WeakPolarHBondContact O-CB 3.36Å; K45-T49 PolarHBondContact O-N 3.4Å; K45-T49 PolarHBondContact O-OG1 2.85Å; K45-F228 HydrophobicContact CD-CD2 3.98Å; K45-F228 HydrophobicContact CD-CE2 4.13Å; K45-F228 HydrophobicContact CD-CG 4.26Å; K45-F228 HydrophobicContact CG-CD2 4.06Å; K45-F228 HydrophobicContact CG-CE2 3.99Å
46	V	89.7	Confident	85.5	Confident	0 Å²	0	66.9 Å²	66.9	0%	0	33%	0.325	C	S	.	.	H	α-helix	trans	-60.7	-52.7	174.6	170.8	0	0	0	0	110.4	F42 I43 L48 T49 N50 L215 F228 A231 H235	F42-V46 HydrophobicContact CE1-CG2 4.14Å; F42-V46 HydrophobicContact CZ-CG2 4.28Å; F42-V46 PolarHBondContact O-N 3.36Å; I43-V46 WeakPolarHBondContact O-CB 3.29Å; I43-V46 PolarHBondContact O-N 2.9Å; I43-V46 VanDerWaalsContact O-N 3.14Å; V46-L48 PolarHBondContact O-N 2.92Å; V46-T49 PolarHBondContact O-N 3.48Å; V46-N50 PolarHBondContact O-N 2.88Å; V46-N50 PolarHBondContact O-ND2 3.09Å; V46-N50 VanDerWaalsContact O-ND2 3.09Å; V46-L215 HydrophobicContact CG1-CD2 4.38Å; V46-L215 HydrophobicContact CG2-CD2 4.29Å; V46-F228 HydrophobicContact CG2-CD2 4.4Å; V46-A231 HydrophobicContact CG2-CB 4.06Å; V46-H235 HydrophobicContact CG1-CB 4.36Å
47	F	90.4	Very high	86.4	Confident	42 Å²	42	63.5 Å²	63.5	18%	0.184	31%	0.307	C	S	.	.	H	α-helix	trans	-61.9	-44.1	179.5	-87.1	-81.5	0	0	0	113.1	I43 L44 T49 N50 I51 F150 H235	I43-F47 HydrophobicContact CG2-CD2 3.73Å; I43-F47 HydrophobicContact CG2-CE2 3.85Å; I43-F47 WeakPolarHBondContact O-CD2 3.46Å; I43-F47 PolarHBondContact O-N 3.31Å; L44-F47 PolarHBondContact O-N 2.75Å; F47-T49 VanDerWaalsContact C-N 3.28Å; F47-T49 PolarHBondContact O-N 3.4Å; F47-N50 PolarHBondContact O-N 3.45Å; F47-I51 VanDerWaalsContact O-CG1 3.27Å; F47-I51 WeakPolarHBondContact O-CG1 3.33Å; F47-I51 PolarHBondContact O-N 3.34Å; F47-F150 HydrophobicContact CE2-CD1 4.03Å; F47-F150 AromaticContact CE2-CD2 3.9Å; F47-F150 HydrophobicContact CE2-CD2 3.9Å; F47-F150 AromaticContact CE2-CE1 3.93Å; F47-F150 HydrophobicContact CE2-CE1 3.93Å; F47-F150 AromaticContact CE2-CE2 3.8Å; F47-F150 HydrophobicContact CE2-CE2 3.8Å; F47-F150 HydrophobicContact CE2-CG 4.02Å; F47-F150 AromaticContact CE2-CZ 3.83Å; F47-F150 HydrophobicContact CE2-CZ 3.83Å; F47-F150 HydrophobicContact CZ-CB 4.15Å; F47-F150 HydrophobicContact CZ-CD1 4.01Å; F47-F150 AromaticContact CZ-CD2 3.76Å; F47-F150 HydrophobicContact CZ-CD2 3.76Å; F47-F150 HydrophobicContact CZ-CE1 4.38Å; F47-F150 HydrophobicContact CZ-CE2 4.16Å; F47-F150 AromaticContact CZ-CG 3.68Å; F47-F150 HydrophobicContact CZ-CG 3.68Å; F47-F150 HydrophobicContact CZ-CZ 4.46Å; F47-H235 AromaticContact CE1-NE2 3.62Å; F47-H235 AromaticContact CZ-CE1 3.96Å; F47-H235 AromaticContact CZ-NE2 3.99Å
48	L	90.7	Very high	87	Confident	123 Å²	123	61.8 Å²	61.8	64%	0.644	29%	0.294	S	S	*	.	H	α-helix	trans	-62	-39.8	179.2	-172.6	71.2	0	0	0	111.5	L44 V46 I51 L52	L44-L48 WeakPolarHBondContact O-CB 3.36Å; L44-L48 PolarHBondContact O-N 3.23Å; V46-L48 PolarHBondContact O-N 2.92Å; L48-I51 PolarHBondContact O-N 3.33Å; L48-L52 PolarHBondContact O-N 2.95Å
49	T	88.1	Confident	87.4	Confident	29 Å²	29	61.6 Å²	61.6	18%	0.178	29%	0.293	C	S	.	.	H	α-helix	trans	-63.6	-47.9	176.5	-53.2	0	0	0	0	110	K45 V46 F47 I51 L52 Q53 Y112 F228	K45-T49 WeakPolarHBondContact O-CB 3.36Å; K45-T49 PolarHBondContact O-N 3.4Å; K45-T49 PolarHBondContact O-OG1 2.85Å; V46-T49 PolarHBondContact O-N 3.48Å; F47-T49 VanDerWaalsContact C-N 3.28Å; F47-T49 PolarHBondContact O-N 3.4Å; T49-I51 PolarHBondContact O-N 3Å; T49-L52 WeakPolarHBondContact O-CB 3.46Å; T49-L52 PolarHBondContact O-N 2.92Å; T49-Q53 WeakPolarHBondContact O-CG 3.34Å; T49-Q53 PolarHBondContact O-N 3.32Å; T49-Q53 VanDerWaalsContact O-N 3.11Å; T49-Y112 HydrophobicContact CG2-CE1 3.75Å; T49-Y112 VanDerWaalsContact CG2-OH 3.32Å; T49-Y112 WeakPolarHBondContact CG2-OH 2.98Å; T49-F228 HydrophobicContact CG2-CE2 4.47Å
50	N	89.8	Confident	87.5	Confident	4 Å²	4	62.7 Å²	62.7	2%	0.021	30%	0.299	C	S	.	.	H	α-helix	trans	-64.6	-36.8	179	-66.2	-36.6	0	0	0	112.9	V46 F47 L52 Q53 V54 S232 H235	V46-N50 PolarHBondContact O-N 2.88Å; V46-N50 PolarHBondContact O-ND2 3.09Å; V46-N50 VanDerWaalsContact O-ND2 3.09Å; F47-N50 PolarHBondContact O-N 3.45Å; N50-L52 VanDerWaalsContact C-N 3.3Å; N50-L52 PolarHBondContact O-N 3.44Å; N50-Q53 PolarHBondContact O-N 3.07Å; N50-Q53 VanDerWaalsContact O-N 3.16Å; N50-Q53 PolarHBondContact OD1-OE1 3.21Å; N50-Q53 VanDerWaalsContact OD1-OE1 3.06Å; N50-V54 WeakPolarHBondContact O-CG2 3.35Å; N50-V54 PolarHBondContact O-N 3.4Å; N50-S232 PolarHBondContact OD1-O 3.44Å; N50-S232 VanDerWaalsContact OD1-O 3.05Å; N50-S232 PolarHBondContact OD1-OG 3.36Å; N50-H235 VanDerWaalsContact ND2-CB 3.34Å; N50-H235 WeakPolarHBondContact ND2-CB 3Å; N50-H235 PolarHBondContact ND2-CD2 3.39Å
51	I	90	Very high	87.4	Confident	107 Å²	107	59.7 Å²	59.7	55%	0.549	28%	0.284	S	S	.	.	H	α-helix	trans	-58.4	-45	174.3	-72.3	164.8	0	0	0	110.5	F47 L48 T49 Q53 V54 F55	F47-I51 VanDerWaalsContact O-CG1 3.27Å; F47-I51 WeakPolarHBondContact O-CG1 3.33Å; F47-I51 PolarHBondContact O-N 3.34Å; L48-I51 PolarHBondContact O-N 3.33Å; T49-I51 PolarHBondContact O-N 3Å; I51-Q53 VanDerWaalsContact C-N 3.29Å; I51-Q53 PolarHBondContact O-N 2.85Å; I51-V54 PolarHBondContact O-N 2.84Å; I51-F55 WeakPolarHBondContact O-CB 3.45Å; I51-F55 PolarHBondContact O-N 3.26Å
52	L	88.4	Confident	87.3	Confident	127 Å²	127	53.2 Å²	53.2	67%	0.665	27%	0.268	S	S	*	.	H	α-helix	trans	-62.6	-39.1	178	-166	75.8	0	0	0	111.4	L48 T49 N50 F55 L56	L48-L52 PolarHBondContact O-N 2.95Å; T49-L52 WeakPolarHBondContact O-CB 3.46Å; T49-L52 PolarHBondContact O-N 2.92Å; N50-L52 VanDerWaalsContact C-N 3.3Å; N50-L52 PolarHBondContact O-N 3.44Å; L52-F55 PolarHBondContact O-N 3.09Å; L52-L56 WeakPolarHBondContact O-CB 3.27Å; L52-L56 PolarHBondContact O-N 2.86Å
53	Q	86.5	Confident	87	Confident	6 Å²	6	55.9 Å²	55.9	3%	0.028	28%	0.283	C	S	.	.	H	α-helix	trans	-69.9	-41.1	178.6	-64	178.7	-46.4	0	0	112.7	T49 N50 I51 F55 L56 S57 Y112 T116 L236	T49-Q53 WeakPolarHBondContact O-CG 3.34Å; T49-Q53 PolarHBondContact O-N 3.32Å; T49-Q53 VanDerWaalsContact O-N 3.11Å; N50-Q53 PolarHBondContact O-N 3.07Å; N50-Q53 VanDerWaalsContact O-N 3.16Å; N50-Q53 PolarHBondContact OD1-OE1 3.21Å; N50-Q53 VanDerWaalsContact OD1-OE1 3.06Å; I51-Q53 VanDerWaalsContact C-N 3.29Å; I51-Q53 PolarHBondContact O-N 2.85Å; Q53-F55 VanDerWaalsContact C-N 3.33Å; Q53-L56 PolarHBondContact O-N 2.99Å; Q53-S57 WeakPolarHBondContact O-CB 3.32Å; Q53-S57 PolarHBondContact O-N 3.01Å; Q53-S57 PolarHBondContact O-OG 3.5Å; Q53-Y112 PolarHBondContact NE2-OH 3.33Å; Q53-Y112 PolarHBondContact OE1-OH 3.47Å; Q53-T116 HydrophobicContact CB-CG2 4.11Å; Q53-T116 HydrophobicContact CG-CG2 3.6Å; Q53-T116 PolarHBondContact NE2-OG1 3.48Å; Q53-L236 HydrophobicContact CB-CD1 4.25Å; Q53-L236 HydrophobicContact CB-CD2 4.35Å
54	V	87.9	Confident	86.4	Confident	11 Å²	11	56.3 Å²	56.3	7%	0.067	29%	0.29	C	S	.	.	H	α-helix	trans	-62.2	-44.7	173.4	170.4	0	0	0	0	109.8	N50 I51 L56 S57 I58 W139 I143 L239	N50-V54 WeakPolarHBondContact O-CG2 3.35Å; N50-V54 PolarHBondContact O-N 3.4Å; I51-V54 PolarHBondContact O-N 2.84Å; V54-L56 PolarHBondContact O-N 2.9Å; V54-S57 WeakPolarHBondContact O-CB 3.38Å; V54-S57 PolarHBondContact O-N 3.04Å; V54-S57 VanDerWaalsContact O-N 3.14Å; V54-I58 HydrophobicContact CG1-CD1 3.81Å; V54-I58 HydrophobicContact CG1-CG1 4.42Å; V54-I58 WeakPolarHBondContact O-CG1 3.31Å; V54-I58 PolarHBondContact O-N 3.42Å; V54-W139 HydrophobicContact CB-CH2 4.48Å; V54-W139 HydrophobicContact CB-CZ3 4.23Å; V54-W139 HydrophobicContact CG1-CD2 4.33Å; V54-W139 HydrophobicContact CG1-CE3 3.73Å; V54-W139 HydrophobicContact CG1-CH2 4.08Å; V54-W139 HydrophobicContact CG1-CZ3 3.61Å; V54-W139 HydrophobicContact CG2-CH2 4.14Å; V54-W139 HydrophobicContact CG2-CZ3 3.76Å; V54-I143 HydrophobicContact CG1-CD1 4.4Å; V54-L239 HydrophobicContact CG2-CD2 3.79Å
55	F	88.5	Confident	85.6	Confident	140 Å²	140	54.1 Å²	54.1	61%	0.614	28%	0.276	S	S	*	.	H	α-helix	trans	-60.1	-45.2	176.3	-173.7	-95.2	0	0	0	111.9	I51 L52 Q53 S57 I58 F59	I51-F55 WeakPolarHBondContact O-CB 3.45Å; I51-F55 PolarHBondContact O-N 3.26Å; L52-F55 PolarHBondContact O-N 3.09Å; Q53-F55 VanDerWaalsContact C-N 3.33Å; F55-S57 VanDerWaalsContact C-N 3.29Å; F55-S57 PolarHBondContact O-N 3.32Å; F55-I58 PolarHBondContact O-N 3.12Å; F55-F59 VanDerWaalsContact O-CB 3.31Å; F55-F59 WeakPolarHBondContact O-CB 3.49Å; F55-F59 PolarHBondContact O-N 3.31Å
56	L	87.2	Confident	84.8	Confident	43 Å²	43	54 Å²	54	23%	0.225	28%	0.284	C	S	.	.	H	α-helix	trans	-60.5	-40.7	174.9	-174	70.6	0	0	0	111.6	L52 Q53 V54 F59 I60 T116 F117	L52-L56 WeakPolarHBondContact O-CB 3.27Å; L52-L56 PolarHBondContact O-N 2.86Å; Q53-L56 PolarHBondContact O-N 2.99Å; V54-L56 PolarHBondContact O-N 2.9Å; L56-F59 PolarHBondContact O-N 3.11Å; L56-I60 HydrophobicContact CD1-CD1 4.2Å; L56-I60 HydrophobicContact CD1-CG1 4.43Å; L56-I60 HydrophobicContact CD2-CD1 4.32Å; L56-I60 HydrophobicContact CG-CD1 3.88Å; L56-I60 HydrophobicContact CG-CG1 4.4Å; L56-I60 WeakPolarHBondContact O-CB 3.38Å; L56-I60 WeakPolarHBondContact O-CG1 3.48Å; L56-I60 PolarHBondContact O-N 2.93Å; L56-T116 HydrophobicContact CD2-CG2 3.79Å; L56-F117 HydrophobicContact CD2-CD1 4.36Å; L56-F117 HydrophobicContact CD2-CE1 4.2Å; L56-F117 HydrophobicContact CD2-CZ 4.33Å
57	S	85.9	Confident	83.7	Confident	2 Å²	2	59.8 Å²	59.8	1%	0.014	32%	0.315	C	S	.	.	H	α-helix	trans	-64.1	-44.8	178.4	-57	0	0	0	0	111.8	Q53 V54 F55 F59 T61	Q53-S57 WeakPolarHBondContact O-CB 3.32Å; Q53-S57 PolarHBondContact O-N 3.01Å; Q53-S57 PolarHBondContact O-OG 3.5Å; V54-S57 WeakPolarHBondContact O-CB 3.38Å; V54-S57 PolarHBondContact O-N 3.04Å; V54-S57 VanDerWaalsContact O-N 3.14Å; F55-S57 VanDerWaalsContact C-N 3.29Å; F55-S57 PolarHBondContact O-N 3.32Å; S57-F59 VanDerWaalsContact C-N 3.34Å; S57-T61 WeakPolarHBondContact O-CB 3.46Å; S57-T61 PolarHBondContact O-N 2.98Å; S57-T61 PolarHBondContact O-OG1 3.3Å
58	I	86	Confident	82	Confident	43 Å²	43	62.8 Å²	62.8	22%	0.221	33%	0.328	C	S	.	.	H	α-helix	trans	-63	-43	174.7	-66.5	167.6	0	0	0	110.2	V54 F55 T61 A62 F136 W139	V54-I58 HydrophobicContact CG1-CD1 3.81Å; V54-I58 HydrophobicContact CG1-CG1 4.42Å; V54-I58 WeakPolarHBondContact O-CG1 3.31Å; V54-I58 PolarHBondContact O-N 3.42Å; F55-I58 PolarHBondContact O-N 3.12Å; I58-T61 PolarHBondContact O-N 3.41Å; I58-A62 WeakPolarHBondContact O-CB 3.38Å; I58-A62 PolarHBondContact O-N 3.35Å; I58-F136 HydrophobicContact CG2-CE1 4.04Å; I58-W139 HydrophobicContact CD1-CD2 4.37Å; I58-W139 HydrophobicContact CD1-CG 4.17Å; I58-W139 HydrophobicContact CG1-CD2 4.25Å; I58-W139 HydrophobicContact CG1-CG 4.14Å
59	F	86.5	Confident	80	Confident	105 Å²	105	66.8 Å²	66.8	46%	0.461	34%	0.34	S	S	.	.	H	α-helix	trans	-64.3	-46.8	179.5	-178.9	-105.5	0	0	0	112.6	F55 L56 S57 T61 A62 L63	F55-F59 VanDerWaalsContact O-CB 3.31Å; F55-F59 WeakPolarHBondContact O-CB 3.49Å; F55-F59 PolarHBondContact O-N 3.31Å; L56-F59 PolarHBondContact O-N 3.11Å; S57-F59 VanDerWaalsContact C-N 3.34Å; F59-T61 VanDerWaalsContact C-N 3.31Å; F59-T61 PolarHBondContact O-N 3Å; F59-A62 PolarHBondContact O-N 3.38Å; F59-L63 HydrophobicContact CD1-CD1 3.84Å; F59-L63 HydrophobicContact CD1-CG 4.4Å; F59-L63 HydrophobicContact CE1-CD1 3.28Å; F59-L63 HydrophobicContact CE1-CG 4.03Å; F59-L63 HydrophobicContact CE2-CD1 4.42Å; F59-L63 HydrophobicContact CE2-CG 4.36Å; F59-L63 HydrophobicContact CZ-CD1 3.62Å; F59-L63 HydrophobicContact CZ-CD2 4.31Å; F59-L63 HydrophobicContact CZ-CG 4Å; F59-L63 WeakPolarHBondContact O-CB 3.44Å; F59-L63 WeakPolarHBondContact O-CG 3.32Å; F59-L63 PolarHBondContact O-N 3.29Å
60	I	82.5	Confident	78.1	Confident	40 Å²	40	69.7 Å²	69.7	21%	0.205	36%	0.36	C	S	.	.	H	α-helix	trans	-62.9	-41.2	176.1	-70.7	174	0	0	0	110.4	L56 L63 A64 F117 A120 A124	L56-I60 HydrophobicContact CD1-CD1 4.2Å; L56-I60 HydrophobicContact CD1-CG1 4.43Å; L56-I60 HydrophobicContact CD2-CD1 4.32Å; L56-I60 HydrophobicContact CG-CD1 3.88Å; L56-I60 HydrophobicContact CG-CG1 4.4Å; L56-I60 WeakPolarHBondContact O-CB 3.38Å; L56-I60 WeakPolarHBondContact O-CG1 3.48Å; L56-I60 PolarHBondContact O-N 2.93Å; I60-L63 PolarHBondContact O-N 2.74Å; I60-A64 WeakPolarHBondContact O-CB 3.35Å; I60-A64 PolarHBondContact O-N 3.43Å; I60-F117 HydrophobicContact CD1-CD1 4.11Å; I60-F117 HydrophobicContact CD1-CE1 4.32Å; I60-A120 HydrophobicContact CD1-CB 3.78Å; I60-A124 HydrophobicContact CG2-CB 4.18Å
61	T	81.1	Confident	76.2	Confident	6 Å²	6	73.9 Å²	73.9	4%	0.037	38%	0.378	C	S	.	.	H	α-helix	trans	-61.6	-47.6	175.6	-54.1	0	0	0	0	110.4	S57 I58 F59 L63 A64 F65 A124 I135	S57-T61 WeakPolarHBondContact O-CB 3.46Å; S57-T61 PolarHBondContact O-N 2.98Å; S57-T61 PolarHBondContact O-OG1 3.3Å; I58-T61 PolarHBondContact O-N 3.41Å; F59-T61 VanDerWaalsContact C-N 3.31Å; F59-T61 PolarHBondContact O-N 3Å; T61-L63 PolarHBondContact O-N 3.15Å; T61-A64 WeakPolarHBondContact O-CB 3.4Å; T61-A64 PolarHBondContact O-N 2.81Å; T61-F65 HydrophobicContact CG2-CD2 4.03Å; T61-F65 HydrophobicContact CG2-CE2 3.83Å; T61-F65 WeakPolarHBondContact O-CD2 3.46Å; T61-F65 PolarHBondContact O-N 3.03Å; T61-A124 WeakPolarHBondContact OG1-CA 3.33Å; T61-I135 HydrophobicContact CG2-CG2 4.43Å
62	A	81.2	Confident	74.1	Confident	40 Å²	40	74 Å²	74	33%	0.331	38%	0.383	S	S	.	.	H	α-helix	trans	-60.2	-43.8	176.7	0	0	0	0	0	112.3	I58 F59 A64 F65 T66	I58-A62 WeakPolarHBondContact O-CB 3.38Å; I58-A62 PolarHBondContact O-N 3.35Å; F59-A62 PolarHBondContact O-N 3.38Å; A62-A64 VanDerWaalsContact C-N 3.33Å; A62-A64 PolarHBondContact O-N 2.82Å; A62-F65 PolarHBondContact O-N 3.37Å; A62-T66 WeakPolarHBondContact O-CG2 3.37Å; A62-T66 PolarHBondContact O-N 3.23Å; A62-T66 PolarHBondContact O-OG1 3.28Å
63	L	80.1	Confident	72.1	Confident	72 Å²	72	75.5 Å²	75.5	38%	0.377	39%	0.385	S	S	.	.	H	α-helix	trans	-62.7	-37.5	175.3	-78.1	-179.3	0	0	0	113	F59 I60 T61 F65 T66 N67	F59-L63 HydrophobicContact CD1-CD1 3.84Å; F59-L63 HydrophobicContact CD1-CG 4.4Å; F59-L63 HydrophobicContact CE1-CD1 3.28Å; F59-L63 HydrophobicContact CE1-CG 4.03Å; F59-L63 HydrophobicContact CE2-CD1 4.42Å; F59-L63 HydrophobicContact CE2-CG 4.36Å; F59-L63 HydrophobicContact CZ-CD1 3.62Å; F59-L63 HydrophobicContact CZ-CD2 4.31Å; F59-L63 HydrophobicContact CZ-CG 4Å; F59-L63 WeakPolarHBondContact O-CB 3.44Å; F59-L63 WeakPolarHBondContact O-CG 3.32Å; F59-L63 PolarHBondContact O-N 3.29Å; I60-L63 PolarHBondContact O-N 2.74Å; T61-L63 PolarHBondContact O-N 3.15Å; L63-F65 VanDerWaalsContact C-N 3.32Å; L63-T66 WeakPolarHBondContact CA-OG1 3.5Å; L63-T66 PolarHBondContact O-N 3.35Å; L63-T66 PolarHBondContact O-OG1 2.99Å; L63-N67 WeakPolarHBondContact O-CB 3.24Å; L63-N67 PolarHBondContact O-N 3.3Å; L63-N67 VanDerWaalsContact O-N 3.07Å; L63-N67 PolarHBondContact O-ND2 3.04Å; L63-N67 VanDerWaalsContact O-ND2 3.09Å
64	A	74.7	Confident	70.4	Confident	29 Å²	29	76.5 Å²	76.5	24%	0.24	39%	0.39	C	S	.	.	H	α-helix	trans	-63.6	-42.3	176.1	0	0	0	0	0	110.5	I60 T61 A62 F68	I60-A64 WeakPolarHBondContact O-CB 3.35Å; I60-A64 PolarHBondContact O-N 3.43Å; T61-A64 WeakPolarHBondContact O-CB 3.4Å; T61-A64 PolarHBondContact O-N 2.81Å; A62-A64 VanDerWaalsContact C-N 3.33Å; A62-A64 PolarHBondContact O-N 2.82Å; A64-F68 WeakPolarHBondContact O-CB 3.39Å; A64-F68 PolarHBondContact O-N 2.79Å
65	F	73.9	Confident	68.7	Low	62 Å²	62	81.3 Å²	81.3	27%	0.272	42%	0.415	S	S	.	.	H	α-helix	trans	-69.8	-35	178	-84.8	-113.5	0	0	0	113.3	T61 A62 L63 F71 I135	T61-F65 HydrophobicContact CG2-CD2 4.03Å; T61-F65 HydrophobicContact CG2-CE2 3.83Å; T61-F65 WeakPolarHBondContact O-CD2 3.46Å; T61-F65 PolarHBondContact O-N 3.03Å; A62-F65 PolarHBondContact O-N 3.37Å; L63-F65 VanDerWaalsContact C-N 3.32Å; F65-F71 HydrophobicContact CD1-CE2 4.12Å; F65-F71 AromaticContact CD1-CZ 3.84Å; F65-F71 HydrophobicContact CD1-CZ 3.84Å; F65-F71 HydrophobicContact CE1-CE1 4.36Å; F65-F71 HydrophobicContact CE1-CE2 4.04Å; F65-F71 AromaticContact CE1-CZ 3.35Å; F65-F71 HydrophobicContact CE1-CZ 3.35Å; F65-F71 HydrophobicContact CE2-CZ 4.33Å; F65-F71 HydrophobicContact CZ-CE1 4.26Å; F65-F71 AromaticContact CZ-CZ 3.6Å; F65-F71 HydrophobicContact CZ-CZ 3.6Å; F65-I135 HydrophobicContact CE1-CD1 3.93Å; F65-I135 HydrophobicContact CE2-CD1 3.87Å; F65-I135 HydrophobicContact CZ-CD1 3.29Å
66	T	72.7	Confident	66.9	Low	103 Å²	103	83.1 Å²	83.1	63%	0.632	42%	0.423	S	S	*	.	H	α-helix	trans	-77.8	-35.5	-179.9	54.2	0	0	0	0	113.4	A62 L63	A62-T66 WeakPolarHBondContact O-CG2 3.37Å; A62-T66 PolarHBondContact O-N 3.23Å; A62-T66 PolarHBondContact O-OG1 3.28Å; L63-T66 WeakPolarHBondContact CA-OG1 3.5Å; L63-T66 PolarHBondContact O-N 3.35Å; L63-T66 PolarHBondContact O-OG1 2.99Å
67	N	65.5	Low	65.8	Low	122 Å²	122	85.9 Å²	85.9	65%	0.652	43%	0.433	S	S	*	.	H	α-helix	trans	-91	-17.1	-175.3	-69.8	-54.2	0	0	0	114.3	L63	L63-N67 WeakPolarHBondContact O-CB 3.24Å; L63-N67 PolarHBondContact O-N 3.3Å; L63-N67 VanDerWaalsContact O-N 3.07Å; L63-N67 PolarHBondContact O-ND2 3.04Å; L63-N67 VanDerWaalsContact O-ND2 3.09Å
68	F	54.8	Low	64.9	Low	105 Å²	105	91.4 Å²	91.4	46%	0.461	46%	0.457	S	S	.	.	S	Bend	trans	-105.1	90	179.2	-79.4	-89.8	0	0	0	112.7	A64 L74	A64-F68 WeakPolarHBondContact O-CB 3.39Å; A64-F68 PolarHBondContact O-N 2.79Å; F68-L74 HydrophobicContact CG-CD1 4.44Å
69	K	49.1	Very low	64.1	Low	206 Å²	206	98.8 Å²	98.8	90%	0.896	48%	0.482	S	S	*	.	S	Bend	trans	-62.8	138.5	157.7	-74.1	-178.4	175.8	179.6	0	109.9
70	P	47.7	Very low	63.5	Low	90 Å²	90	98.9 Å²	98.9	58%	0.584	48%	0.483	S	S	*	.	S	Bend		-76.5	151.7	-87.2	36.2	-25.3	0	0	0	112.7	V72	P70-V72 HydrophobicContact CG-CG2 4.46Å; P70-V72 PolarHBondContact O-N 2.84Å
71	F	49.4	Very low	63.1	Low	92 Å²	92	98 Å²	98	40%	0.404	48%	0.48	S	S	.	.	G	3₁₀ helix	trans	24.7	-28.1	144.7	-78.2	-94	0	0	0	123.2	F65 K73 I128	F65-F71 HydrophobicContact CD1-CE2 4.12Å; F65-F71 AromaticContact CD1-CZ 3.84Å; F65-F71 HydrophobicContact CD1-CZ 3.84Å; F65-F71 HydrophobicContact CE1-CE1 4.36Å; F65-F71 HydrophobicContact CE1-CE2 4.04Å; F65-F71 AromaticContact CE1-CZ 3.35Å; F65-F71 HydrophobicContact CE1-CZ 3.35Å; F65-F71 HydrophobicContact CE2-CZ 4.33Å; F65-F71 HydrophobicContact CZ-CE1 4.26Å; F65-F71 AromaticContact CZ-CZ 3.6Å; F65-F71 HydrophobicContact CZ-CZ 3.6Å; F71-K73 PolarHBondContact O-N 3.06Å; F71-I128 HydrophobicContact CD1-CG2 3.46Å; F71-I128 VanDerWaalsContact CD1-CG2 3.46Å; F71-I128 HydrophobicContact CE1-CB 4.07Å; F71-I128 HydrophobicContact CE1-CG2 3.45Å; F71-I128 VanDerWaalsContact CE1-CG2 3.45Å; F71-I128 WeakPolarHBondContact CE1-O 3.3Å
72	V	46.6	Very low	62.7	Low	110 Å²	110	99.8 Å²	99.8	67%	0.667	49%	0.492	S	S	*	.	G	3₁₀ helix	trans	-73.6	-21.7	-171.9	-175.3	0	0	0	0	113.6	P70	P70-V72 HydrophobicContact CG-CG2 4.46Å; P70-V72 PolarHBondContact O-N 2.84Å
73	K	46.4	Very low	62.7	Low	159 Å²	159	102.4 Å²	102.4	69%	0.691	50%	0.499	S	S	*	.	G	3₁₀ helix	trans	-89.9	-18.4	179.9	-83.3	-172.5	179.8	177.8	0	114.9	F71	F71-K73 PolarHBondContact O-N 3.06Å
74	L	50.4	Low	62.7	Low	27 Å²	27	100.1 Å²	100.1	14%	0.141	49%	0.488	C	S	.	.	T	Hydrogen-bonded Turn	trans	-86.5	-26.8	-176.1	-93	148.3	0	0	0	113	F68 K76 K77 F125 I128	F68-L74 HydrophobicContact CG-CD1 4.44Å; L74-K76 PolarHBondContact O-N 3.25Å; L74-K77 HydrophobicContact CD2-CB 4.49Å; L74-K77 CarbonylContact O-C 3.5Å; L74-K77 WeakPolarHBondContact O-CA 3.18Å; L74-K77 WeakPolarHBondContact O-CB 3.12Å; L74-K77 PolarHBondContact O-N 3.32Å; L74-F125 HydrophobicContact CD2-CD1 3.77Å; L74-F125 HydrophobicContact CD2-CE1 3.07Å; L74-F125 HydrophobicContact CD2-CE2 4.46Å; L74-F125 HydrophobicContact CD2-CZ 3.46Å; L74-F125 VanDerWaalsContact CD2-CZ 3.46Å; L74-F125 HydrophobicContact CG-CE1 4.48Å; L74-I128 HydrophobicContact CB-CD1 3.77Å; L74-I128 HydrophobicContact CD1-CD1 3.74Å; L74-I128 HydrophobicContact CD2-CD1 3.84Å; L74-I128 HydrophobicContact CG-CD1 3.96Å
75	D	52.4	Low	63	Low	111 Å²	111	101 Å²	101	59%	0.594	49%	0.492	S	S	*	.	G	3₁₀ helix	trans	-62.1	-31.7	171.9	-144.7	24.8	0	0	0	111.4	K77	D75-K77 PolarHBondContact O-N 3.13Å
76	K	52	Low	63.4	Low	179 Å²	179	103.1 Å²	103.1	78%	0.778	51%	0.51	S	S	*	.	G	3₁₀ helix	trans	-70.4	-6.5	169.7	-66.3	-169.7	177.4	-174	0	114.5	L74	L74-K76 PolarHBondContact O-N 3.25Å
77	K	63.9	Low	63.9	Low	101 Å²	101	101.8 Å²	101.8	44%	0.439	50%	0.498	S	S	.	.	G	3₁₀ helix	trans	-115.3	21.4	-177.2	-66.3	-168.1	178.4	-170.9	0	113	L74 D75 W79 F80 F125	L74-K77 HydrophobicContact CD2-CB 4.49Å; L74-K77 CarbonylContact O-C 3.5Å; L74-K77 WeakPolarHBondContact O-CA 3.18Å; L74-K77 WeakPolarHBondContact O-CB 3.12Å; L74-K77 PolarHBondContact O-N 3.32Å; D75-K77 PolarHBondContact O-N 3.13Å; K77-W79 PolarHBondContact O-N 3.1Å; K77-F80 HydrophobicContact CB-CB 4.21Å; K77-F80 WeakPolarHBondContact O-CA 3.03Å; K77-F80 VanDerWaalsContact O-CB 3.3Å; K77-F80 WeakPolarHBondContact O-CB 3.29Å; K77-F80 PolarHBondContact O-N 3.28Å; K77-F125 HydrophobicContact CB-CE1 4.23Å
78	F	66.5	Low	64.7	Low	118 Å²	118	96.3 Å²	96.3	52%	0.518	47%	0.469	S	S	.	.	H	α-helix	trans	-46.2	-39.3	169.7	-177.7	-100.1	0	0	0	112.2	F80 S81 C82	F78-F80 VanDerWaalsContact C-N 3.28Å; F78-F80 PolarHBondContact O-N 3.01Å; F78-S81 WeakPolarHBondContact O-CB 3.28Å; F78-S81 PolarHBondContact O-N 3.03Å; F78-C82 WeakPolarHBondContact CE1-SG 3.04Å; F78-C82 PolarHBondContact O-N 3.33Å
79	W	70	Confident	66	Low	197 Å²	197	97.5 Å²	97.5	75%	0.746	48%	0.478	S	S	*	.	H	α-helix	trans	-54.8	-36.1	173	-72.9	106.1	0	0	0	114.8	K77 C82 I83	K77-W79 PolarHBondContact O-N 3.1Å; W79-C82 PolarHBondContact O-N 3.05Å; W79-I83 VanDerWaalsContact O-CG1 3.25Å; W79-I83 WeakPolarHBondContact O-CG1 3.41Å; W79-I83 PolarHBondContact O-N 3.21Å
80	F	73.3	Confident	67.7	Low	108 Å²	108	89.7 Å²	89.7	47%	0.474	46%	0.455	S	S	.	.	H	α-helix	trans	-67.6	-38.1	177.6	-160.6	-93.3	0	0	0	111.2	K77 F78 I83 L84 F125	K77-F80 HydrophobicContact CB-CB 4.21Å; K77-F80 WeakPolarHBondContact O-CA 3.03Å; K77-F80 VanDerWaalsContact O-CB 3.3Å; K77-F80 WeakPolarHBondContact O-CB 3.29Å; K77-F80 PolarHBondContact O-N 3.28Å; F78-F80 VanDerWaalsContact C-N 3.28Å; F78-F80 PolarHBondContact O-N 3.01Å; F80-I83 PolarHBondContact O-N 3.46Å; F80-L84 HydrophobicContact CD1-CD1 3.73Å; F80-L84 HydrophobicContact CD1-CG 4.01Å; F80-L84 HydrophobicContact CE1-CD1 3.67Å; F80-L84 HydrophobicContact CE1-CD2 4.24Å; F80-L84 HydrophobicContact CE1-CG 3.93Å; F80-L84 WeakPolarHBondContact O-CB 3.38Å; F80-L84 WeakPolarHBondContact O-CG 3.5Å; F80-L84 PolarHBondContact O-N 2.88Å; F80-F125 HydrophobicContact CB-CE1 4.49Å; F80-F125 HydrophobicContact CB-CZ 3.97Å; F80-F125 AromaticContact CD1-CE2 3.6Å; F80-F125 HydrophobicContact CD1-CE2 3.6Å; F80-F125 AromaticContact CD1-CZ 3.59Å; F80-F125 HydrophobicContact CD1-CZ 3.59Å; F80-F125 HydrophobicContact CE1-CE2 4.29Å; F80-F125 HydrophobicContact CG-CZ 4.17Å
81	S	72.6	Confident	69.4	Low	21 Å²	21	86 Å²	86	15%	0.147	43%	0.43	C	S	.	.	H	α-helix	trans	-63.7	-42.4	172.3	-174.6	0	0	0	0	111.5	F78 I83 L84 S85	F78-S81 WeakPolarHBondContact O-CB 3.28Å; F78-S81 PolarHBondContact O-N 3.03Å; S81-I83 PolarHBondContact O-N 3.17Å; S81-L84 PolarHBondContact O-N 2.87Å; S81-S85 WeakPolarHBondContact O-CB 3.45Å; S81-S85 PolarHBondContact O-N 3.09Å; S81-S85 PolarHBondContact O-OG 3.25Å
82	C	74.3	Confident	71	Confident	43 Å²	43	84 Å²	84	29%	0.291	43%	0.426	S	S	.	.	H	α-helix	trans	-60.5	-45.4	174.2	-68.4	0	0	0	0	112	F78 W79 S85 V86	F78-C82 WeakPolarHBondContact CE1-SG 3.04Å; F78-C82 PolarHBondContact O-N 3.33Å; W79-C82 PolarHBondContact O-N 3.05Å; C82-S85 PolarHBondContact O-N 3.07Å; C82-V86 VanDerWaalsContact O-CG2 3.32Å; C82-V86 WeakPolarHBondContact O-CG2 3.46Å; C82-V86 PolarHBondContact O-N 3.31Å
83	I	81	Confident	72.8	Confident	95 Å²	95	83 Å²	83	49%	0.487	42%	0.416	S	S	.	.	H	α-helix	trans	-61.5	-48.8	178.1	-69.4	163.5	0	0	0	110.5	W79 F80 S81 S85 V86 I87	W79-I83 VanDerWaalsContact O-CG1 3.25Å; W79-I83 WeakPolarHBondContact O-CG1 3.41Å; W79-I83 PolarHBondContact O-N 3.21Å; F80-I83 PolarHBondContact O-N 3.46Å; S81-I83 PolarHBondContact O-N 3.17Å; I83-S85 VanDerWaalsContact C-N 3.3Å; I83-S85 PolarHBondContact O-N 3.17Å; I83-V86 PolarHBondContact O-N 3.18Å; I83-I87 HydrophobicContact CG2-CD1 3.78Å; I83-I87 HydrophobicContact CG2-CG1 4.46Å; I83-I87 VanDerWaalsContact O-CG1 3.31Å; I83-I87 WeakPolarHBondContact O-CG1 3.48Å; I83-I87 PolarHBondContact O-N 3.33Å
84	L	80.4	Confident	74.6	Confident	25 Å²	25	76.9 Å²	76.9	13%	0.131	40%	0.395	C	S	.	.	H	α-helix	trans	-59	-42.6	176.4	-72.6	178.1	0	0	0	111.7	F80 S81 V86 I87 S88 V122 F125	F80-L84 HydrophobicContact CD1-CD1 3.73Å; F80-L84 HydrophobicContact CD1-CG 4.01Å; F80-L84 HydrophobicContact CE1-CD1 3.67Å; F80-L84 HydrophobicContact CE1-CD2 4.24Å; F80-L84 HydrophobicContact CE1-CG 3.93Å; F80-L84 WeakPolarHBondContact O-CB 3.38Å; F80-L84 WeakPolarHBondContact O-CG 3.5Å; F80-L84 PolarHBondContact O-N 2.88Å; S81-L84 PolarHBondContact O-N 2.87Å; L84-V86 PolarHBondContact O-N 2.97Å; L84-I87 PolarHBondContact O-N 3.02Å; L84-S88 PolarHBondContact O-N 2.93Å; L84-S88 PolarHBondContact O-OG 2.65Å; L84-S88 VanDerWaalsContact O-OG 3.04Å; L84-V122 HydrophobicContact CB-CG2 3.78Å; L84-F125 HydrophobicContact CD1-CD2 4.3Å; L84-F125 HydrophobicContact CD1-CE2 4.06Å
85	S	79.5	Confident	76.3	Confident	48 Å²	48	75.6 Å²	75.6	34%	0.336	39%	0.388	S	S	.	.	H	α-helix	trans	-62.6	-42	178.1	-57.5	0	0	0	0	112.1	S81 C82 I83 S88 M89	S81-S85 WeakPolarHBondContact O-CB 3.45Å; S81-S85 PolarHBondContact O-N 3.09Å; S81-S85 PolarHBondContact O-OG 3.25Å; C82-S85 PolarHBondContact O-N 3.07Å; I83-S85 VanDerWaalsContact C-N 3.3Å; I83-S85 PolarHBondContact O-N 3.17Å; S85-S88 PolarHBondContact O-N 3.49Å; S85-M89 WeakPolarHBondContact O-CB 3.2Å; S85-M89 PolarHBondContact O-N 2.94Å
86	V	83.4	Confident	77.7	Confident	105 Å²	105	73 Å²	73	64%	0.636	37%	0.372	S	S	*	.	H	α-helix	trans	-65.3	-41	175.9	171.6	0	0	0	0	110.8	C82 I83 L84 M89 G90	C82-V86 VanDerWaalsContact O-CG2 3.32Å; C82-V86 WeakPolarHBondContact O-CG2 3.46Å; C82-V86 PolarHBondContact O-N 3.31Å; I83-V86 PolarHBondContact O-N 3.18Å; L84-V86 PolarHBondContact O-N 2.97Å; V86-M89 PolarHBondContact O-N 3.46Å; V86-G90 PolarHBondContact O-N 3.42Å
87	I	83.3	Confident	79.2	Confident	76 Å²	76	69.7 Å²	69.7	39%	0.39	36%	0.358	S	S	.	.	H	α-helix	trans	-61	-50.5	174.6	-69.9	167.9	0	0	0	110.1	I83 L84 M89 G90 E91	I83-I87 HydrophobicContact CG2-CD1 3.78Å; I83-I87 HydrophobicContact CG2-CG1 4.46Å; I83-I87 VanDerWaalsContact O-CG1 3.31Å; I83-I87 WeakPolarHBondContact O-CG1 3.48Å; I83-I87 PolarHBondContact O-N 3.33Å; L84-I87 PolarHBondContact O-N 3.02Å; I87-M89 VanDerWaalsContact C-N 3.27Å; I87-M89 PolarHBondContact O-N 3.18Å; I87-G90 PolarHBondContact O-N 3.39Å; I87-G90 VanDerWaalsContact O-N 3.12Å; I87-E91 HydrophobicContact CG2-CG 4.24Å; I87-E91 VanDerWaalsContact CG2-OE1 3.28Å; I87-E91 WeakPolarHBondContact CG2-OE1 3.42Å; I87-E91 WeakPolarHBondContact O-CB 3.41Å; I87-E91 VanDerWaalsContact O-CG 3.29Å; I87-E91 WeakPolarHBondContact O-CG 3.43Å; I87-E91 PolarHBondContact O-N 3.38Å
88	S	82	Confident	80.1	Confident	7 Å²	7	66.4 Å²	66.4	5%	0.049	35%	0.345	C	S	.	.	H	α-helix	trans	-59.1	-38	177.9	-56.7	0	0	0	0	112.3	L84 S85 T92 S118	L84-S88 PolarHBondContact O-N 2.93Å; L84-S88 PolarHBondContact O-OG 2.65Å; L84-S88 VanDerWaalsContact O-OG 3.04Å; S85-S88 PolarHBondContact O-N 3.49Å; S88-T92 WeakPolarHBondContact O-CB 3.42Å; S88-T92 PolarHBondContact O-N 3.19Å; S88-T92 PolarHBondContact O-OG1 3.07Å; S88-S118 WeakPolarHBondContact OG-CB 3.47Å; S88-S118 PolarHBondContact OG-OG 3.36Å
89	M	82.5	Confident	80.6	Confident	130 Å²	130	62.2 Å²	62.2	64%	0.64	33%	0.327	S	S	*	.	H	α-helix	trans	-67.5	-44.5	175.8	-169.8	173.4	179.4	0	0	111.6	S85 V86 I87 T92 I93	S85-M89 WeakPolarHBondContact O-CB 3.2Å; S85-M89 PolarHBondContact O-N 2.94Å; V86-M89 PolarHBondContact O-N 3.46Å; I87-M89 VanDerWaalsContact C-N 3.27Å; I87-M89 PolarHBondContact O-N 3.18Å; M89-T92 PolarHBondContact O-N 3.13Å; M89-I93 HydrophobicContact CG-CD1 4.44Å; M89-I93 WeakPolarHBondContact O-CG1 3.28Å; M89-I93 PolarHBondContact O-N 3.43Å; M89-I93 VanDerWaalsContact O-N 3.11Å
90	G	83.7	Confident	80.8	Confident	41 Å²	41	59.4 Å²	59.4	42%	0.423	32%	0.316	S	S	.	.	H	α-helix	trans	-61	-43.6	174.9	0	0	0	0	0	112.6	V86 I87 T92 I93 A94	V86-G90 PolarHBondContact O-N 3.42Å; I87-G90 PolarHBondContact O-N 3.39Å; I87-G90 VanDerWaalsContact O-N 3.12Å; G90-T92 PolarHBondContact O-N 3.29Å; G90-I93 PolarHBondContact O-N 3.37Å; G90-A94 WeakPolarHBondContact O-CB 3.46Å; G90-A94 PolarHBondContact O-N 3.26Å
91	E	82.9	Confident	81.1	Confident	12 Å²	12	59.2 Å²	59.2	6%	0.056	32%	0.315	C	S	.	.	H	α-helix	trans	-63	-40.5	175.8	-72.7	165.4	163.4	0	0	111.8	I87 I93 A94 I95 L114 F115 S118	I87-E91 HydrophobicContact CG2-CG 4.24Å; I87-E91 VanDerWaalsContact CG2-OE1 3.28Å; I87-E91 WeakPolarHBondContact CG2-OE1 3.42Å; I87-E91 WeakPolarHBondContact O-CB 3.41Å; I87-E91 VanDerWaalsContact O-CG 3.29Å; I87-E91 WeakPolarHBondContact O-CG 3.43Å; I87-E91 PolarHBondContact O-N 3.38Å; E91-I93 VanDerWaalsContact C-N 3.35Å; E91-I93 PolarHBondContact O-N 3Å; E91-A94 PolarHBondContact O-N 3.39Å; E91-I95 WeakPolarHBondContact O-CB 3.46Å; E91-I95 WeakPolarHBondContact O-CD1 3.38Å; E91-I95 VanDerWaalsContact O-CG1 3.25Å; E91-I95 WeakPolarHBondContact O-CG1 3.44Å; E91-I95 PolarHBondContact O-N 2.68Å; E91-L114 WeakPolarHBondContact OE1-CD2 3.35Å; E91-L114 WeakPolarHBondContact OE1-CG 3.43Å; E91-F115 HydrophobicContact CB-CB 4.26Å; E91-F115 HydrophobicContact CB-CD2 4.18Å; E91-F115 WeakPolarHBondContact OE2-CA 3.41Å; E91-F115 PolarHBondContact OE2-N 3.07Å; E91-S118 PolarHBondContact OE2-OG 3.15Å
92	T	83.5	Confident	81.1	Confident	51 Å²	51	63.4 Å²	63.4	31%	0.313	34%	0.342	S	S	.	.	H	α-helix	trans	-60.1	-46	175.7	-57	0	0	0	0	111.6	S88 M89 G90 F96 F115 M233	S88-T92 WeakPolarHBondContact O-CB 3.42Å; S88-T92 PolarHBondContact O-N 3.19Å; S88-T92 PolarHBondContact O-OG1 3.07Å; M89-T92 PolarHBondContact O-N 3.13Å; G90-T92 PolarHBondContact O-N 3.29Å; T92-F96 WeakPolarHBondContact O-CB 3.43Å; T92-F96 PolarHBondContact O-N 3.41Å; T92-F96 VanDerWaalsContact O-N 3.08Å; T92-F115 WeakPolarHBondContact OG1-CE2 3.48Å; T92-M233 HydrophobicContact CG2-CE 3.99Å
93	I	84.9	Confident	81.4	Confident	88 Å²	88	68 Å²	68	45%	0.451	36%	0.359	S	S	.	.	H	α-helix	trans	-64.8	-45.5	177	-63.9	166.7	0	0	0	110	M89 G90 E91 F96 F97	M89-I93 HydrophobicContact CG-CD1 4.44Å; M89-I93 WeakPolarHBondContact O-CG1 3.28Å; M89-I93 PolarHBondContact O-N 3.43Å; M89-I93 VanDerWaalsContact O-N 3.11Å; G90-I93 PolarHBondContact O-N 3.37Å; E91-I93 VanDerWaalsContact C-N 3.35Å; E91-I93 PolarHBondContact O-N 3Å; I93-F96 PolarHBondContact O-N 3.25Å; I93-F97 HydrophobicContact CG2-CD2 3.9Å; I93-F97 HydrophobicContact CG2-CE2 3.66Å; I93-F97 WeakPolarHBondContact O-CD2 2.93Å; I93-F97 PolarHBondContact O-N 3.36Å
94	A	85.1	Confident	81.4	Confident	31 Å²	31	66.2 Å²	66.2	26%	0.256	35%	0.35	S	S	.	.	H	α-helix	trans	-60.6	-48.7	179.7	0	0	0	0	0	111.9	G90 E91 F96 F97 I98 L111	G90-A94 WeakPolarHBondContact O-CB 3.46Å; G90-A94 PolarHBondContact O-N 3.26Å; E91-A94 PolarHBondContact O-N 3.39Å; A94-F96 VanDerWaalsContact C-N 3.31Å; A94-F96 PolarHBondContact O-N 2.86Å; A94-F97 PolarHBondContact O-N 2.95Å; A94-I98 HydrophobicContact CB-CD1 4.21Å; A94-I98 WeakPolarHBondContact O-CB 3.26Å; A94-I98 VanDerWaalsContact O-CG1 3.24Å; A94-I98 WeakPolarHBondContact O-CG1 3.47Å; A94-I98 PolarHBondContact O-N 3.38Å; A94-L111 HydrophobicContact CB-CD1 4.28Å
95	I	84.4	Confident	81.4	Confident	0 Å²	0	71.2 Å²	71.2	0%	0	37%	0.371	C	S	.	.	H	α-helix	trans	-60.5	-42.4	178.3	-70	163.2	0	0	0	110.3	E91 F97 I98 Q99 T108 L111 Y112 F115 I229 M233	E91-I95 WeakPolarHBondContact O-CB 3.46Å; E91-I95 WeakPolarHBondContact O-CD1 3.38Å; E91-I95 VanDerWaalsContact O-CG1 3.25Å; E91-I95 WeakPolarHBondContact O-CG1 3.44Å; E91-I95 PolarHBondContact O-N 2.68Å; I95-F97 PolarHBondContact O-N 3.06Å; I95-I98 PolarHBondContact O-N 2.93Å; I95-Q99 WeakPolarHBondContact O-CB 3.45Å; I95-Q99 WeakPolarHBondContact O-CG 3.27Å; I95-Q99 PolarHBondContact O-N 3.12Å; I95-T108 HydrophobicContact CG2-CG2 4.02Å; I95-L111 HydrophobicContact CD1-CB 4.04Å; I95-L111 HydrophobicContact CG1-CB 3.76Å; I95-L111 HydrophobicContact CG1-CD1 4.42Å; I95-Y112 HydrophobicContact CD1-CD2 4.46Å; I95-F115 HydrophobicContact CD1-CB 4.33Å; I95-I229 HydrophobicContact CG2-CG2 3.92Å; I95-M233 HydrophobicContact CB-SD 4Å; I95-M233 HydrophobicContact CD1-CE 3.78Å; I95-M233 HydrophobicContact CD1-SD 3.65Å; I95-M233 HydrophobicContact CG1-SD 4.43Å; I95-M233 HydrophobicContact CG2-SD 3.6Å
96	F	82.6	Confident	81.7	Confident	57 Å²	57	78.6 Å²	78.6	25%	0.25	39%	0.392	C	S	.	.	H	α-helix	trans	-58.7	-34.8	178.7	178.6	-103.7	0	0	0	113.6	T92 I93 A94 F230	T92-F96 WeakPolarHBondContact O-CB 3.43Å; T92-F96 PolarHBondContact O-N 3.41Å; T92-F96 VanDerWaalsContact O-N 3.08Å; I93-F96 PolarHBondContact O-N 3.25Å; A94-F96 VanDerWaalsContact C-N 3.31Å; A94-F96 PolarHBondContact O-N 2.86Å; F96-F230 HydrophobicContact CB-CE2 4.5Å; F96-F230 AromaticContact CD2-CD2 3.98Å; F96-F230 HydrophobicContact CD2-CD2 3.98Å; F96-F230 HydrophobicContact CD2-CE1 4.49Å; F96-F230 AromaticContact CD2-CE2 3.47Å; F96-F230 HydrophobicContact CD2-CE2 3.47Å; F96-F230 VanDerWaalsContact CD2-CE2 3.47Å; F96-F230 AromaticContact CD2-CZ 3.76Å; F96-F230 HydrophobicContact CD2-CZ 3.76Å; F96-F230 HydrophobicContact CE2-CE1 4.47Å; F96-F230 HydrophobicContact CE2-CE2 4.12Å; F96-F230 AromaticContact CE2-CZ 3.91Å; F96-F230 HydrophobicContact CE2-CZ 3.91Å; F96-F230 HydrophobicContact CG-CE2 4.39Å
97	F	83.2	Confident	81.8	Confident	110 Å²	110	77.2 Å²	77.2	48%	0.482	38%	0.381	S	S	.	.	H	α-helix	trans	-83.3	-45.8	176	-73.6	-67.5	0	0	0	112.6	I93 A94 I95 R100	I93-F97 HydrophobicContact CG2-CD2 3.9Å; I93-F97 HydrophobicContact CG2-CE2 3.66Å; I93-F97 WeakPolarHBondContact O-CD2 2.93Å; I93-F97 PolarHBondContact O-N 3.36Å; A94-F97 PolarHBondContact O-N 2.95Å; I95-F97 PolarHBondContact O-N 3.06Å; F97-R100 PolarHBondContact O-N 3.14Å
98	I	82.7	Confident	81.8	Confident	31 Å²	31	73.8 Å²	73.8	16%	0.159	36%	0.364	C	S	.	.	H	α-helix	trans	-71.5	-34.7	-172.9	-65.8	167.5	0	0	0	111.5	A94 I95 R100 F101 L104 L107 T108 L111	A94-I98 HydrophobicContact CB-CD1 4.21Å; A94-I98 WeakPolarHBondContact O-CB 3.26Å; A94-I98 VanDerWaalsContact O-CG1 3.24Å; A94-I98 WeakPolarHBondContact O-CG1 3.47Å; A94-I98 PolarHBondContact O-N 3.38Å; I95-I98 PolarHBondContact O-N 2.93Å; I98-R100 PolarHBondContact O-N 3.49Å; I98-F101 WeakPolarHBondContact O-CB 3.37Å; I98-F101 PolarHBondContact O-N 3.07Å; I98-L104 HydrophobicContact CG2-CB 3.72Å; I98-L104 HydrophobicContact CG2-CD1 3.93Å; I98-L104 HydrophobicContact CG2-CG 4.48Å; I98-L107 HydrophobicContact CD1-CD2 4.08Å; I98-L107 HydrophobicContact CG2-CD2 4.21Å; I98-L107 HydrophobicContact CG2-CG 4.45Å; I98-T108 WeakPolarHBondContact CG2-OG1 3.48Å; I98-L111 HydrophobicContact CD1-CD1 3.48Å; I98-L111 VanDerWaalsContact CD1-CD1 3.48Å
99	Q	77.2	Confident	81.9	Confident	30 Å²	30	76.6 Å²	76.6	14%	0.14	38%	0.378	C	S	.	.	T	Hydrogen-bonded Turn	trans	-59.2	-19.3	-178.9	72.9	178.6	-17.1	0	0	113.8	I95 F101 T108	I95-Q99 WeakPolarHBondContact O-CB 3.45Å; I95-Q99 WeakPolarHBondContact O-CG 3.27Å; I95-Q99 PolarHBondContact O-N 3.12Å; Q99-F101 PolarHBondContact O-N 3.13Å; Q99-T108 HydrophobicContact CB-CG2 4.03Å
100	R	73.8	Confident	82.2	Confident	138 Å²	138	76.2 Å²	76.2	52%	0.521	37%	0.373	S	S	.	.	T	Hydrogen-bonded Turn	trans	-71.6	-17.3	176.8	-58.7	-177.5	-171.1	-176.2	3.3	112.9	F97 I98 P102	F97-R100 PolarHBondContact O-N 3.14Å; I98-R100 PolarHBondContact O-N 3.49Å; R100-P102 VanDerWaalsContact O-CD 3.24Å; R100-P102 WeakPolarHBondContact O-CD 3.44Å
101	F	80.2	Confident	82.3	Confident	105 Å²	105	75.6 Å²	75.6	46%	0.461	36%	0.36	S	S	.	.			trans	-102.2	98.1	-177.4	-64	-67.7	0	0	0	109	I98 Q99 H103 L104	I98-F101 WeakPolarHBondContact O-CB 3.37Å; I98-F101 PolarHBondContact O-N 3.07Å; Q99-F101 PolarHBondContact O-N 3.13Å; F101-H103 AromaticContact CD1-CE1 3.72Å; F101-H103 AromaticContact CG-CE1 3.93Å; F101-H103 PolarHBondContact O-N 3.19Å; F101-L104 HydrophobicContact CB-CB 4.28Å; F101-L104 HydrophobicContact CB-CD1 3.93Å; F101-L104 HydrophobicContact CB-CG 4.11Å; F101-L104 HydrophobicContact CD2-CD1 4.34Å; F101-L104 HydrophobicContact CG-CD1 4.38Å; F101-L104 PolarHBondContact O-N 3.24Å
102	P	71.9	Confident	82.5	Confident	109 Å²	109	76 Å²	76	71%	0.708	36%	0.361	S	S	*	.	G	3₁₀ helix	trans	-61.5	-23.8	-174.5	21.9	-32.4	0	0	0	113	R100 L104 K105	R100-P102 VanDerWaalsContact O-CD 3.24Å; R100-P102 WeakPolarHBondContact O-CD 3.44Å; P102-L104 VanDerWaalsContact C-N 3.27Å; P102-L104 PolarHBondContact O-N 3.26Å; P102-K105 PolarHBondContact O-N 3.27Å
103	H	81.1	Confident	82.6	Confident	140 Å²	140	78.4 Å²	78.4	65%	0.648	37%	0.371	S	S	*	.	G	3₁₀ helix	trans	-71.2	-18.8	175.3	63.2	-88.2	0	0	0	113.6	F101 K105	F101-H103 AromaticContact CD1-CE1 3.72Å; F101-H103 AromaticContact CG-CE1 3.93Å; F101-H103 PolarHBondContact O-N 3.19Å; H103-K105 VanDerWaalsContact C-N 3.35Å
104	L	82	Confident	82.6	Confident	56 Å²	56	77.8 Å²	77.8	29%	0.293	37%	0.369	S	S	.	.	G	3₁₀ helix	trans	-95.8	18.5	178.1	-63.7	177.8	0	0	0	112.9	I98 F101 P102 Y106 L107 T108	I98-L104 HydrophobicContact CG2-CB 3.72Å; I98-L104 HydrophobicContact CG2-CD1 3.93Å; I98-L104 HydrophobicContact CG2-CG 4.48Å; F101-L104 HydrophobicContact CB-CB 4.28Å; F101-L104 HydrophobicContact CB-CD1 3.93Å; F101-L104 HydrophobicContact CB-CG 4.11Å; F101-L104 HydrophobicContact CD2-CD1 4.34Å; F101-L104 HydrophobicContact CG-CD1 4.38Å; F101-L104 PolarHBondContact O-N 3.24Å; P102-L104 VanDerWaalsContact C-N 3.27Å; P102-L104 PolarHBondContact O-N 3.26Å; L104-Y106 VanDerWaalsContact C-N 3.29Å; L104-Y106 PolarHBondContact O-N 3.31Å; L104-L107 HydrophobicContact CB-CB 4.39Å; L104-L107 HydrophobicContact CD2-CD2 4.48Å; L104-L107 WeakPolarHBondContact O-CA 3.44Å; L104-L107 WeakPolarHBondContact O-CB 3.16Å; L104-L107 PolarHBondContact O-N 3.08Å; L104-T108 PolarHBondContact O-N 3.39Å; L104-T108 PolarHBondContact O-OG1 3.07Å
105	K	80.5	Confident	82.7	Confident	131 Å²	131	76.6 Å²	76.6	57%	0.57	36%	0.358	S	S	*	.	H	α-helix	trans	-49.7	-46.1	-176.7	-174.4	-177.4	174.6	-172.1	0	113.6	P102 H103 L107 T108 D109	P102-K105 PolarHBondContact O-N 3.27Å; H103-K105 VanDerWaalsContact C-N 3.35Å; K105-L107 VanDerWaalsContact C-N 3.3Å; K105-L107 PolarHBondContact O-N 3.47Å; K105-T108 WeakPolarHBondContact O-CB 3.39Å; K105-T108 PolarHBondContact O-N 2.68Å; K105-D109 PolarHBondContact O-N 3.35Å
106	Y	84	Confident	82.7	Confident	202 Å²	202	77.3 Å²	77.3	79%	0.792	36%	0.362	S	S	*	.	H	α-helix	trans	-63	-35.8	178.9	-68.7	-74.8	0	0	0	113	L104 F110	L104-Y106 VanDerWaalsContact C-N 3.29Å; L104-Y106 PolarHBondContact O-N 3.31Å; Y106-F110 WeakPolarHBondContact O-CB 3.17Å; Y106-F110 PolarHBondContact O-N 3.08Å
107	L	86.8	Confident	82.7	Confident	76 Å²	76	79.7 Å²	79.7	40%	0.398	37%	0.373	S	S	.	.	H	α-helix	trans	-69	-42	175.6	-179	62.9	0	0	0	110.6	I98 L104 K105 F110 L111	I98-L107 HydrophobicContact CD1-CD2 4.08Å; I98-L107 HydrophobicContact CG2-CD2 4.21Å; I98-L107 HydrophobicContact CG2-CG 4.45Å; L104-L107 HydrophobicContact CB-CB 4.39Å; L104-L107 HydrophobicContact CD2-CD2 4.48Å; L104-L107 WeakPolarHBondContact O-CA 3.44Å; L104-L107 WeakPolarHBondContact O-CB 3.16Å; L104-L107 PolarHBondContact O-N 3.08Å; K105-L107 VanDerWaalsContact C-N 3.3Å; K105-L107 PolarHBondContact O-N 3.47Å; L107-F110 PolarHBondContact O-N 3.5Å; L107-L111 HydrophobicContact CD1-CD1 4.43Å; L107-L111 HydrophobicContact CD1-CG 4.39Å; L107-L111 HydrophobicContact CG-CD1 4.15Å; L107-L111 WeakPolarHBondContact O-CB 3.33Å; L107-L111 VanDerWaalsContact O-CG 3.3Å; L107-L111 WeakPolarHBondContact O-CG 3.42Å; L107-L111 PolarHBondContact O-N 2.81Å
108	T	83.5	Confident	82.7	Confident	5 Å²	5	74.8 Å²	74.8	3%	0.031	35%	0.352	C	S	.	.	H	α-helix	trans	-61	-45.2	174.9	-44.8	0	0	0	0	111.5	I95 I98 Q99 L104 K105 F110 L111 Y112 I229	I95-T108 HydrophobicContact CG2-CG2 4.02Å; I98-T108 WeakPolarHBondContact CG2-OG1 3.48Å; Q99-T108 HydrophobicContact CB-CG2 4.03Å; L104-T108 PolarHBondContact O-N 3.39Å; L104-T108 PolarHBondContact O-OG1 3.07Å; K105-T108 WeakPolarHBondContact O-CB 3.39Å; K105-T108 PolarHBondContact O-N 2.68Å; T108-F110 PolarHBondContact O-N 2.84Å; T108-L111 PolarHBondContact O-N 2.89Å; T108-Y112 WeakPolarHBondContact O-CB 3.5Å; T108-Y112 PolarHBondContact O-N 3.44Å; T108-I229 HydrophobicContact CG2-CD1 3.67Å
109	D	84.1	Confident	82.7	Confident	66 Å²	66	74.2 Å²	74.2	35%	0.353	35%	0.349	S	S	.	.	H	α-helix	trans	-63.5	-41.2	178.3	-70.8	-20.4	0	0	0	111.3	K105 Y112 L113 I229	K105-D109 PolarHBondContact O-N 3.35Å; D109-Y112 PolarHBondContact O-N 3.35Å; D109-L113 PolarHBondContact O-N 2.99Å; D109-I229 WeakPolarHBondContact OD1-CD1 3.41Å
110	F	87.2	Confident	82.9	Confident	122 Å²	122	72.8 Å²	72.8	54%	0.535	34%	0.342	S	S	.	.	H	α-helix	trans	-64.2	-47.8	175.4	176.2	-100.4	0	0	0	112.4	Y106 L107 T108 Y112 L113 L114	Y106-F110 WeakPolarHBondContact O-CB 3.17Å; Y106-F110 PolarHBondContact O-N 3.08Å; L107-F110 PolarHBondContact O-N 3.5Å; T108-F110 PolarHBondContact O-N 2.84Å; F110-Y112 PolarHBondContact O-N 3.37Å; F110-L113 WeakPolarHBondContact O-CB 3.42Å; F110-L113 PolarHBondContact O-N 3.35Å; F110-L114 PolarHBondContact O-N 3.05Å
111	L	87.4	Confident	83.2	Confident	27 Å²	27	66.8 Å²	66.8	14%	0.141	32%	0.323	C	S	.	.	H	α-helix	trans	-60.8	-37.1	176.7	-73.6	171.9	0	0	0	111.4	A94 I95 I98 L107 T108 L114 F115	A94-L111 HydrophobicContact CB-CD1 4.28Å; I95-L111 HydrophobicContact CD1-CB 4.04Å; I95-L111 HydrophobicContact CG1-CB 3.76Å; I95-L111 HydrophobicContact CG1-CD1 4.42Å; I98-L111 HydrophobicContact CD1-CD1 3.48Å; I98-L111 VanDerWaalsContact CD1-CD1 3.48Å; L107-L111 HydrophobicContact CD1-CD1 4.43Å; L107-L111 HydrophobicContact CD1-CG 4.39Å; L107-L111 HydrophobicContact CG-CD1 4.15Å; L107-L111 WeakPolarHBondContact O-CB 3.33Å; L107-L111 VanDerWaalsContact O-CG 3.3Å; L107-L111 WeakPolarHBondContact O-CG 3.42Å; L107-L111 PolarHBondContact O-N 2.81Å; T108-L111 PolarHBondContact O-N 2.89Å; L111-L114 PolarHBondContact O-N 2.99Å; L111-F115 VanDerWaalsContact O-CB 3.31Å; L111-F115 WeakPolarHBondContact O-CB 3.42Å; L111-F115 PolarHBondContact O-N 2.68Å
112	Y	85.7	Confident	83.2	Confident	21 Å²	21	63 Å²	63	8%	0.082	31%	0.308	C	S	.	.	H	α-helix	trans	-68.4	-36.5	177.2	-175.2	-114.2	0	0	0	113	T49 Q53 I95 T108 D109 F110 F115 T116 I229 S232 M233	T49-Y112 HydrophobicContact CG2-CE1 3.75Å; T49-Y112 VanDerWaalsContact CG2-OH 3.32Å; T49-Y112 WeakPolarHBondContact CG2-OH 2.98Å; Q53-Y112 PolarHBondContact NE2-OH 3.33Å; Q53-Y112 PolarHBondContact OE1-OH 3.47Å; I95-Y112 HydrophobicContact CD1-CD2 4.46Å; T108-Y112 WeakPolarHBondContact O-CB 3.5Å; T108-Y112 PolarHBondContact O-N 3.44Å; D109-Y112 PolarHBondContact O-N 3.35Å; F110-Y112 PolarHBondContact O-N 3.37Å; Y112-F115 HydrophobicContact CD2-CD1 4.32Å; Y112-F115 HydrophobicContact CE2-CD1 4.34Å; Y112-F115 PolarHBondContact O-N 3.43Å; Y112-T116 PolarHBondContact O-N 3.36Å; Y112-T116 PolarHBondContact O-OG1 3.47Å; Y112-I229 HydrophobicContact CD1-CG2 4.41Å; Y112-I229 HydrophobicContact CD2-CG2 3.46Å; Y112-I229 VanDerWaalsContact CD2-CG2 3.46Å; Y112-I229 HydrophobicContact CE2-CG2 3.93Å; Y112-I229 HydrophobicContact CG-CG2 3.71Å; Y112-S232 WeakPolarHBondContact OH-CB 3.46Å; Y112-S232 PolarHBondContact OH-OG 3.08Å; Y112-M233 HydrophobicContact CD2-CG 3.85Å; Y112-M233 HydrophobicContact CD2-SD 4.18Å; Y112-M233 HydrophobicContact CE2-CG 3.5Å; Y112-M233 HydrophobicContact CE2-SD 4.42Å
113	L	86	Confident	83.7	Confident	101 Å²	101	57.9 Å²	57.9	53%	0.529	28%	0.275	S	S	.	.	H	α-helix	trans	-62.7	-47.2	171.7	-169	90.7	0	0	0	110.6	D109 F110 F115 T116 F117	D109-L113 PolarHBondContact O-N 2.99Å; F110-L113 WeakPolarHBondContact O-CB 3.42Å; F110-L113 PolarHBondContact O-N 3.35Å; L113-F115 VanDerWaalsContact C-N 3.32Å; L113-F115 PolarHBondContact O-N 2.69Å; L113-T116 WeakPolarHBondContact O-CB 3.44Å; L113-T116 PolarHBondContact O-N 2.85Å; L113-T116 VanDerWaalsContact O-N 3.14Å; L113-F117 HydrophobicContact CG-CD2 4.38Å; L113-F117 HydrophobicContact CG-CE2 4.31Å; L113-F117 WeakPolarHBondContact O-CD2 3.45Å; L113-F117 PolarHBondContact O-N 3.46Å
114	L	86.2	Confident	83.7	Confident	76 Å²	76	51.7 Å²	51.7	40%	0.398	25%	0.248	S	C	.	.	H	α-helix	trans	-61.5	-42.7	178.6	-165.5	66.9	0	0	0	111.3	E91 F110 L111 T116 F117 S118	E91-L114 WeakPolarHBondContact OE1-CD2 3.35Å; E91-L114 WeakPolarHBondContact OE1-CG 3.43Å; F110-L114 PolarHBondContact O-N 3.05Å; L111-L114 PolarHBondContact O-N 2.99Å; L114-T116 VanDerWaalsContact C-N 3.32Å; L114-T116 PolarHBondContact O-N 3.49Å; L114-F117 PolarHBondContact O-N 3.35Å; L114-F117 VanDerWaalsContact O-N 3.16Å; L114-S118 PolarHBondContact O-N 3Å; L114-S118 PolarHBondContact O-OG 3.4Å
115	F	86.6	Confident	83.4	Confident	5 Å²	5	50.3 Å²	50.3	2%	0.022	24%	0.239	C	C	.	.	H	α-helix	trans	-55.6	-45.2	171.8	175.6	-97.2	0	0	0	112.6	E91 T92 I95 L111 Y112 L113 F117 S118 F119 M233 L236	E91-F115 HydrophobicContact CB-CB 4.26Å; E91-F115 HydrophobicContact CB-CD2 4.18Å; E91-F115 WeakPolarHBondContact OE2-CA 3.41Å; E91-F115 PolarHBondContact OE2-N 3.07Å; T92-F115 WeakPolarHBondContact OG1-CE2 3.48Å; I95-F115 HydrophobicContact CD1-CB 4.33Å; L111-F115 VanDerWaalsContact O-CB 3.31Å; L111-F115 WeakPolarHBondContact O-CB 3.42Å; L111-F115 PolarHBondContact O-N 2.68Å; Y112-F115 HydrophobicContact CD2-CD1 4.32Å; Y112-F115 HydrophobicContact CE2-CD1 4.34Å; Y112-F115 PolarHBondContact O-N 3.43Å; L113-F115 VanDerWaalsContact C-N 3.32Å; L113-F115 PolarHBondContact O-N 2.69Å; F115-F117 VanDerWaalsContact C-N 3.29Å; F115-F117 PolarHBondContact O-N 2.89Å; F115-S118 WeakPolarHBondContact CA-OG 3.49Å; F115-S118 PolarHBondContact O-N 3.4Å; F115-S118 PolarHBondContact O-OG 2.91Å; F115-F119 HydrophobicContact CE1-CB 4.48Å; F115-F119 HydrophobicContact CE1-CG 4.48Å; F115-F119 HydrophobicContact CE2-CD2 4.24Å; F115-F119 HydrophobicContact CZ-CB 4.41Å; F115-F119 AromaticContact CZ-CD2 3.95Å; F115-F119 HydrophobicContact CZ-CD2 3.95Å; F115-F119 HydrophobicContact CZ-CE2 4.37Å; F115-F119 HydrophobicContact CZ-CG 4.19Å; F115-F119 WeakPolarHBondContact O-CB 3.24Å; F115-F119 PolarHBondContact O-N 3.2Å; F115-M233 HydrophobicContact CD1-CE 3.91Å; F115-M233 HydrophobicContact CD1-CG 4.42Å; F115-M233 HydrophobicContact CD2-CE 3.79Å; F115-M233 HydrophobicContact CE1-CE 3.85Å; F115-M233 HydrophobicContact CE1-CG 4.18Å; F115-M233 HydrophobicContact CE2-CE 3.73Å; F115-M233 HydrophobicContact CG-CE 3.88Å; F115-M233 HydrophobicContact CZ-CE 3.76Å; F115-L236 HydrophobicContact CE1-CD2 3.8Å
116	T	83.9	Confident	83.3	Confident	16 Å²	16	47 Å²	47	10%	0.098	23%	0.228	C	C	.	.	H	α-helix	trans	-60	-41.9	178.8	-58.1	0	0	0	0	111.5	Q53 L56 Y112 L113 L114 A120	Q53-T116 HydrophobicContact CB-CG2 4.11Å; Q53-T116 HydrophobicContact CG-CG2 3.6Å; Q53-T116 PolarHBondContact NE2-OG1 3.48Å; L56-T116 HydrophobicContact CD2-CG2 3.79Å; Y112-T116 PolarHBondContact O-N 3.36Å; Y112-T116 PolarHBondContact O-OG1 3.47Å; L113-T116 WeakPolarHBondContact O-CB 3.44Å; L113-T116 PolarHBondContact O-N 2.85Å; L113-T116 VanDerWaalsContact O-N 3.14Å; L114-T116 VanDerWaalsContact C-N 3.32Å; L114-T116 PolarHBondContact O-N 3.49Å; T116-A120 VanDerWaalsContact O-CB 3.24Å; T116-A120 WeakPolarHBondContact O-CB 3.38Å; T116-A120 PolarHBondContact O-N 3.4Å
117	F	82.9	Confident	83.1	Confident	106 Å²	106	37.3 Å²	37.3	47%	0.465	19%	0.19	S	C	.	.	H	α-helix	trans	-70.8	-44.9	177.5	-86.1	-77.5	0	0	0	112.9	L56 I60 L113 L114 F115 F119 A120 G121	L56-F117 HydrophobicContact CD2-CD1 4.36Å; L56-F117 HydrophobicContact CD2-CE1 4.2Å; L56-F117 HydrophobicContact CD2-CZ 4.33Å; I60-F117 HydrophobicContact CD1-CD1 4.11Å; I60-F117 HydrophobicContact CD1-CE1 4.32Å; L113-F117 HydrophobicContact CG-CD2 4.38Å; L113-F117 HydrophobicContact CG-CE2 4.31Å; L113-F117 WeakPolarHBondContact O-CD2 3.45Å; L113-F117 PolarHBondContact O-N 3.46Å; L114-F117 PolarHBondContact O-N 3.35Å; L114-F117 VanDerWaalsContact O-N 3.16Å; F115-F117 VanDerWaalsContact C-N 3.29Å; F115-F117 PolarHBondContact O-N 2.89Å; F117-F119 VanDerWaalsContact C-N 3.29Å; F117-F119 PolarHBondContact O-N 3.16Å; F117-A120 PolarHBondContact O-N 3.14Å; F117-G121 PolarHBondContact O-N 2.95Å
118	S	83.6	Confident	82.5	Confident	7 Å²	7	35 Å²	35	5%	0.049	18%	0.178	C	C	.	.	H	α-helix	trans	-60.9	-43.7	179.3	66.2	0	0	0	0	110.3	S88 E91 L114 F115 G121 V122	S88-S118 WeakPolarHBondContact OG-CB 3.47Å; S88-S118 PolarHBondContact OG-OG 3.36Å; E91-S118 PolarHBondContact OE2-OG 3.15Å; L114-S118 PolarHBondContact O-N 3Å; L114-S118 PolarHBondContact O-OG 3.4Å; F115-S118 WeakPolarHBondContact CA-OG 3.49Å; F115-S118 PolarHBondContact O-N 3.4Å; F115-S118 PolarHBondContact O-OG 2.91Å; S118-G121 WeakPolarHBondContact O-CA 3.5Å; S118-G121 PolarHBondContact O-N 2.96Å; S118-V122 WeakPolarHBondContact O-CG2 3.31Å; S118-V122 PolarHBondContact O-N 2.85Å
119	F	81.5	Confident	81.9	Confident	20 Å²	20	39.9 Å²	39.9	9%	0.088	20%	0.196	C	C	.	.	H	α-helix	trans	-69.2	-43.3	179.7	-161.4	-105.5	0	0	0	113.4	F115 F117 G121 V122 I123 L236 T240	F115-F119 HydrophobicContact CE1-CB 4.48Å; F115-F119 HydrophobicContact CE1-CG 4.48Å; F115-F119 HydrophobicContact CE2-CD2 4.24Å; F115-F119 HydrophobicContact CZ-CB 4.41Å; F115-F119 AromaticContact CZ-CD2 3.95Å; F115-F119 HydrophobicContact CZ-CD2 3.95Å; F115-F119 HydrophobicContact CZ-CE2 4.37Å; F115-F119 HydrophobicContact CZ-CG 4.19Å; F115-F119 WeakPolarHBondContact O-CB 3.24Å; F115-F119 PolarHBondContact O-N 3.2Å; F117-F119 VanDerWaalsContact C-N 3.29Å; F117-F119 PolarHBondContact O-N 3.16Å; F119-G121 PolarHBondContact O-N 3.36Å; F119-V122 PolarHBondContact O-N 3.23Å; F119-V122 VanDerWaalsContact O-N 3.13Å; F119-I123 HydrophobicContact CD1-CD1 3.95Å; F119-I123 HydrophobicContact CE1-CD1 3.98Å; F119-I123 WeakPolarHBondContact O-CG1 3.46Å; F119-I123 PolarHBondContact O-N 3.17Å; F119-L236 HydrophobicContact CD1-CD1 4.25Å; F119-L236 HydrophobicContact CD1-CD2 3.7Å; F119-L236 HydrophobicContact CD1-CG 3.89Å; F119-L236 HydrophobicContact CE1-CD1 3.91Å; F119-L236 HydrophobicContact CE1-CD2 3.87Å; F119-L236 HydrophobicContact CE1-CG 3.52Å; F119-L236 HydrophobicContact CG-CD2 4.47Å; F119-L236 HydrophobicContact CZ-CG 4.36Å; F119-T240 HydrophobicContact CE1-CG2 3.85Å; F119-T240 WeakPolarHBondContact CE1-OG1 3.35Å; F119-T240 HydrophobicContact CE2-CG2 4.43Å; F119-T240 VanDerWaalsContact CZ-CB 3.43Å; F119-T240 HydrophobicContact CZ-CG2 3.6Å; F119-T240 WeakPolarHBondContact CZ-OG1 3.25Å
120	A	83	Confident	81.5	Confident	0 Å²	0	37.3 Å²	37.3	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-59.3	-36.3	172.2	0	0	0	0	0	111.8	I60 T116 F117 I123 A124	I60-A120 HydrophobicContact CD1-CB 3.78Å; T116-A120 VanDerWaalsContact O-CB 3.24Å; T116-A120 WeakPolarHBondContact O-CB 3.38Å; T116-A120 PolarHBondContact O-N 3.4Å; F117-A120 PolarHBondContact O-N 3.14Å; A120-I123 PolarHBondContact O-N 3.28Å; A120-A124 PolarHBondContact O-N 3.41Å
121	G	79.3	Confident	80.8	Confident	12 Å²	12	35.1 Å²	35.1	12%	0.124	17%	0.174	C	C	.	.	H	α-helix	trans	-58.3	-52.8	170.8	0	0	0	0	0	112.1	F117 S118 F119 I123 A124 F125	F117-G121 PolarHBondContact O-N 2.95Å; S118-G121 WeakPolarHBondContact O-CA 3.5Å; S118-G121 PolarHBondContact O-N 2.96Å; F119-G121 PolarHBondContact O-N 3.36Å; G121-I123 VanDerWaalsContact C-N 3.26Å; G121-I123 PolarHBondContact O-N 3.47Å; G121-A124 WeakPolarHBondContact O-CB 3.47Å; G121-A124 PolarHBondContact O-N 3.36Å; G121-A124 VanDerWaalsContact O-N 3.1Å; G121-F125 VanDerWaalsContact O-CD2 3.27Å; G121-F125 WeakPolarHBondContact O-CD2 3.37Å; G121-F125 PolarHBondContact O-N 2.87Å
122	V	80.8	Confident	80.1	Confident	25 Å²	25	35.3 Å²	35.3	15%	0.152	18%	0.183	C	C	.	.	H	α-helix	trans	-55	-42.6	177.9	176.8	0	0	0	0	111.5	L84 S118 F119 F125 L126	L84-V122 HydrophobicContact CB-CG2 3.78Å; S118-V122 WeakPolarHBondContact O-CG2 3.31Å; S118-V122 PolarHBondContact O-N 2.85Å; F119-V122 PolarHBondContact O-N 3.23Å; F119-V122 VanDerWaalsContact O-N 3.13Å; V122-F125 PolarHBondContact O-N 2.96Å; V122-L126 PolarHBondContact O-N 3.3Å
123	I	82.3	Confident	80	Confident	2 Å²	2	40.2 Å²	40.2	1%	0.01	21%	0.208	C	C	.	.	H	α-helix	trans	-65.2	-43.5	177.9	-60.7	169.8	0	0	0	111.6	F119 A120 G121 F125 L126 S127 W139 T240 Y243	F119-I123 HydrophobicContact CD1-CD1 3.95Å; F119-I123 HydrophobicContact CE1-CD1 3.98Å; F119-I123 WeakPolarHBondContact O-CG1 3.46Å; F119-I123 PolarHBondContact O-N 3.17Å; A120-I123 PolarHBondContact O-N 3.28Å; G121-I123 VanDerWaalsContact C-N 3.26Å; G121-I123 PolarHBondContact O-N 3.47Å; I123-F125 PolarHBondContact O-N 3.24Å; I123-L126 PolarHBondContact O-N 3.39Å; I123-L126 VanDerWaalsContact O-N 3.15Å; I123-S127 WeakPolarHBondContact O-CB 3.06Å; I123-S127 PolarHBondContact O-N 3.5Å; I123-S127 PolarHBondContact O-OG 2.83Å; I123-W139 HydrophobicContact CD1-CH2 3.99Å; I123-W139 HydrophobicContact CD1-CZ2 4.09Å; I123-W139 HydrophobicContact CG2-CZ2 3.7Å; I123-T240 HydrophobicContact CD1-CG2 3.93Å; I123-T240 WeakPolarHBondContact CD1-OG1 3.45Å; I123-T240 HydrophobicContact CG1-CG2 3.69Å; I123-Y243 HydrophobicContact CG2-CD1 4.02Å; I123-Y243 HydrophobicContact CG2-CE1 3.61Å
124	A	80.1	Confident	79.9	Confident	9 Å²	9	36.4 Å²	36.4	7%	0.074	19%	0.187	C	C	.	.	H	α-helix	trans	-58.6	-40.1	177	0	0	0	0	0	111.1	I60 T61 A120 G121 S127 I128	I60-A124 HydrophobicContact CG2-CB 4.18Å; T61-A124 WeakPolarHBondContact OG1-CA 3.33Å; A120-A124 PolarHBondContact O-N 3.41Å; G121-A124 WeakPolarHBondContact O-CB 3.47Å; G121-A124 PolarHBondContact O-N 3.36Å; G121-A124 VanDerWaalsContact O-N 3.1Å; A124-S127 PolarHBondContact O-N 3.48Å; A124-I128 WeakPolarHBondContact O-CG1 3.43Å
125	F	76.9	Confident	79.9	Confident	27 Å²	27	33.2 Å²	33.2	12%	0.118	17%	0.171	C	C	.	.	H	α-helix	trans	-64.5	-43.5	174	-85.3	-86.9	0	0	0	113.1	L74 K77 F80 L84 G121 V122 I123 S127 I128	L74-F125 HydrophobicContact CD2-CD1 3.77Å; L74-F125 HydrophobicContact CD2-CE1 3.07Å; L74-F125 HydrophobicContact CD2-CE2 4.46Å; L74-F125 HydrophobicContact CD2-CZ 3.46Å; L74-F125 VanDerWaalsContact CD2-CZ 3.46Å; L74-F125 HydrophobicContact CG-CE1 4.48Å; K77-F125 HydrophobicContact CB-CE1 4.23Å; F80-F125 HydrophobicContact CB-CE1 4.49Å; F80-F125 HydrophobicContact CB-CZ 3.97Å; F80-F125 AromaticContact CD1-CE2 3.6Å; F80-F125 HydrophobicContact CD1-CE2 3.6Å; F80-F125 AromaticContact CD1-CZ 3.59Å; F80-F125 HydrophobicContact CD1-CZ 3.59Å; F80-F125 HydrophobicContact CE1-CE2 4.29Å; F80-F125 HydrophobicContact CG-CZ 4.17Å; L84-F125 HydrophobicContact CD1-CD2 4.3Å; L84-F125 HydrophobicContact CD1-CE2 4.06Å; G121-F125 VanDerWaalsContact O-CD2 3.27Å; G121-F125 WeakPolarHBondContact O-CD2 3.37Å; G121-F125 PolarHBondContact O-N 2.87Å; V122-F125 PolarHBondContact O-N 2.96Å; I123-F125 PolarHBondContact O-N 3.24Å; F125-S127 PolarHBondContact O-N 3.37Å; F125-I128 HydrophobicContact CD1-CD1 4.11Å; F125-I128 WeakPolarHBondContact O-CB 3.23Å; F125-I128 PolarHBondContact O-N 2.94Å
126	L	77	Confident	79.8	Confident	61 Å²	61	38.4 Å²	38.4	32%	0.319	19%	0.193	S	C	.	.	H	α-helix	trans	-61.5	-32.2	177.8	-155.1	109.3	0	0	0	111.8	V122 I123 I128 Y243 I247	V122-L126 PolarHBondContact O-N 3.3Å; I123-L126 PolarHBondContact O-N 3.39Å; I123-L126 VanDerWaalsContact O-N 3.15Å; L126-I128 VanDerWaalsContact C-N 3.26Å; L126-I128 PolarHBondContact O-N 2.97Å; L126-Y243 HydrophobicContact CD2-CD1 4.22Å; L126-Y243 HydrophobicContact CD2-CE1 4.09Å; L126-I247 HydrophobicContact CD2-CB 4.09Å; L126-I247 HydrophobicContact CD2-CG1 4.28Å; L126-I247 HydrophobicContact CD2-CG2 3.82Å; L126-I247 HydrophobicContact CG-CG2 4.49Å
127	S	79.6	Confident	80.1	Confident	0 Å²	0	40.7 Å²	40.7	0%	0	20%	0.204	C	C	.	.	G	3₁₀ helix	trans	-75.8	-12.3	-177.2	-50.9	0	0	0	0	113.5	I123 A124 F125 Y129 I135 Y243	I123-S127 WeakPolarHBondContact O-CB 3.06Å; I123-S127 PolarHBondContact O-N 3.5Å; I123-S127 PolarHBondContact O-OG 2.83Å; A124-S127 PolarHBondContact O-N 3.48Å; F125-S127 PolarHBondContact O-N 3.37Å; S127-Y129 PolarHBondContact O-N 2.9Å; S127-I135 VanDerWaalsContact O-CD1 3.24Å; S127-I135 WeakPolarHBondContact O-CD1 3.47Å; S127-Y243 PolarHBondContact OG-OH 3.35Å
128	I	75.1	Confident	80.5	Confident	28 Å²	28	35.7 Å²	35.7	14%	0.144	18%	0.182	C	C	.	.	G	3₁₀ helix	trans	-68.2	-24.3	178.9	-64.2	172.2	0	0	0	111.4	F71 L74 A124 F125 L126 V130	F71-I128 HydrophobicContact CD1-CG2 3.46Å; F71-I128 VanDerWaalsContact CD1-CG2 3.46Å; F71-I128 HydrophobicContact CE1-CB 4.07Å; F71-I128 HydrophobicContact CE1-CG2 3.45Å; F71-I128 VanDerWaalsContact CE1-CG2 3.45Å; F71-I128 WeakPolarHBondContact CE1-O 3.3Å; L74-I128 HydrophobicContact CB-CD1 3.77Å; L74-I128 HydrophobicContact CD1-CD1 3.74Å; L74-I128 HydrophobicContact CD2-CD1 3.84Å; L74-I128 HydrophobicContact CG-CD1 3.96Å; A124-I128 WeakPolarHBondContact O-CG1 3.43Å; F125-I128 HydrophobicContact CD1-CD1 4.11Å; F125-I128 WeakPolarHBondContact O-CB 3.23Å; F125-I128 PolarHBondContact O-N 2.94Å; L126-I128 VanDerWaalsContact C-N 3.26Å; L126-I128 PolarHBondContact O-N 2.97Å; I128-V130 PolarHBondContact O-N 3.18Å
129	Y	70.7	Confident	80.9	Confident	107 Å²	107	35.6 Å²	35.6	42%	0.42	18%	0.181	S	C	.	.	G	3₁₀ helix	trans	-81	-1	-174.2	-63	-72	0	0	0	114.2	S127	S127-Y129 PolarHBondContact O-N 2.9Å
130	V	76.3	Confident	81.4	Confident	11 Å²	11	39.3 Å²	39.3	7%	0.067	20%	0.201	C	C	.	.	S	Bend	trans	-134.2	148.9	-174.6	-165.7	0	0	0	0	110.2	I128 F134 I247 F250	I128-V130 PolarHBondContact O-N 3.18Å; V130-F134 HydrophobicContact CG1-CB 3.47Å; V130-F134 VanDerWaalsContact CG1-CB 3.47Å; V130-F134 HydrophobicContact CG1-CD2 4.07Å; V130-F134 HydrophobicContact CG1-CG 4.14Å; V130-I247 HydrophobicContact CB-CD1 4.32Å; V130-I247 HydrophobicContact CG2-CD1 3.98Å; V130-I247 HydrophobicContact CG2-CG2 3.72Å; V130-F250 HydrophobicContact CG1-CB 4.06Å
131	E	72.3	Confident	81.9	Confident	76 Å²	76	42.3 Å²	42.3	36%	0.355	22%	0.216	S	C	.	.			trans	-57.3	147.3	173.1	-62.7	-176.3	170.1	0	0	112.3	M133 F134 L255	E131-M133 VanDerWaalsContact C-N 3.25Å; E131-M133 PolarHBondContact O-N 3.26Å; E131-M133 VanDerWaalsContact O-N 3.08Å; E131-F134 HydrophobicContact CB-CD2 4.09Å; E131-F134 PolarHBondContact O-N 3.18Å; E131-L255 WeakPolarHBondContact OE2-CD1 3.44Å
132	G	72.4	Confident	82.6	Confident	32 Å²	32	41.7 Å²	41.7	33%	0.33	21%	0.21	S	C	.	.	H	α-helix	trans	-53.5	-36.2	-170.4	0	0	0	0	0	114.9	I135 F136	G132-I135 WeakPolarHBondContact O-CB 3.45Å; G132-I135 PolarHBondContact O-N 3.24Å; G132-F136 VanDerWaalsContact O-CD2 3.23Å; G132-F136 WeakPolarHBondContact O-CD2 3.38Å
133	M	82.5	Confident	83.2	Confident	124 Å²	124	44 Å²	44	61%	0.611	22%	0.221	S	C	*	.	H	α-helix	trans	-67.2	-41.2	-179.9	-80.9	-178.2	47.2	0	0	113.1	E131 I135 F136 I137	E131-M133 VanDerWaalsContact C-N 3.25Å; E131-M133 PolarHBondContact O-N 3.26Å; E131-M133 VanDerWaalsContact O-N 3.08Å; M133-I135 VanDerWaalsContact C-N 3.25Å; M133-I135 PolarHBondContact O-N 3.29Å; M133-F136 PolarHBondContact O-N 3.35Å; M133-I137 WeakPolarHBondContact O-CG1 3.24Å; M133-I137 PolarHBondContact O-N 3.37Å; M133-I137 VanDerWaalsContact O-N 3.12Å
134	F	85.4	Confident	83.8	Confident	21 Å²	21	48.1 Å²	48.1	9%	0.092	24%	0.242	C	C	.	.	H	α-helix	trans	-70.5	-22.9	-177.9	-67	-67.5	0	0	0	112.7	V130 E131 I137 S138 F250 I253 L255	V130-F134 HydrophobicContact CG1-CB 3.47Å; V130-F134 VanDerWaalsContact CG1-CB 3.47Å; V130-F134 HydrophobicContact CG1-CD2 4.07Å; V130-F134 HydrophobicContact CG1-CG 4.14Å; E131-F134 HydrophobicContact CB-CD2 4.09Å; E131-F134 PolarHBondContact O-N 3.18Å; F134-I137 HydrophobicContact CD1-CD1 4.18Å; F134-I137 PolarHBondContact O-N 3.37Å; F134-S138 VanDerWaalsContact O-CB 3.26Å; F134-S138 WeakPolarHBondContact O-CB 3.34Å; F134-S138 PolarHBondContact O-N 3.3Å; F134-S138 PolarHBondContact O-OG 3.06Å; F134-F250 HydrophobicContact CB-CB 4.01Å; F134-F250 HydrophobicContact CB-CD2 4.13Å; F134-F250 HydrophobicContact CB-CG 4.22Å; F134-F250 HydrophobicContact CD1-CB 4.18Å; F134-F250 HydrophobicContact CD1-CD1 4.09Å; F134-F250 HydrophobicContact CD1-CD2 4.29Å; F134-F250 AromaticContact CD1-CG 3.94Å; F134-F250 HydrophobicContact CD1-CG 3.94Å; F134-F250 HydrophobicContact CE1-CD1 4.49Å; F134-F250 HydrophobicContact CG-CB 4.08Å; F134-F250 HydrophobicContact CG-CG 4.27Å; F134-I253 HydrophobicContact CE1-CD1 4.46Å; F134-I253 HydrophobicContact CE1-CG2 4.24Å; F134-I253 HydrophobicContact CE2-CB 4.2Å; F134-I253 HydrophobicContact CE2-CG2 4.02Å; F134-I253 HydrophobicContact CZ-CB 4Å; F134-I253 HydrophobicContact CZ-CG2 3.49Å; F134-I253 VanDerWaalsContact CZ-CG2 3.49Å; F134-L255 HydrophobicContact CE2-CD1 3.97Å; F134-L255 HydrophobicContact CE2-CG 3.99Å; F134-L255 HydrophobicContact CZ-CD1 4.12Å; F134-L255 HydrophobicContact CZ-CD2 4.23Å; F134-L255 HydrophobicContact CZ-CG 4.02Å
135	I	85.6	Confident	84.5	Confident	9 Å²	9	49.5 Å²	49.5	5%	0.046	25%	0.248	C	C	.	.	H	α-helix	trans	-59.8	-49.8	170.7	-64.8	165.5	0	0	0	110.2	T61 F65 S127 G132 M133 S138 W139 Y243 I247	T61-I135 HydrophobicContact CG2-CG2 4.43Å; F65-I135 HydrophobicContact CE1-CD1 3.93Å; F65-I135 HydrophobicContact CE2-CD1 3.87Å; F65-I135 HydrophobicContact CZ-CD1 3.29Å; S127-I135 VanDerWaalsContact O-CD1 3.24Å; S127-I135 WeakPolarHBondContact O-CD1 3.47Å; G132-I135 WeakPolarHBondContact O-CB 3.45Å; G132-I135 PolarHBondContact O-N 3.24Å; M133-I135 VanDerWaalsContact C-N 3.25Å; M133-I135 PolarHBondContact O-N 3.29Å; I135-S138 PolarHBondContact O-N 2.83Å; I135-W139 PolarHBondContact O-N 3Å; I135-W139 VanDerWaalsContact O-N 3.08Å; I135-Y243 WeakPolarHBondContact CG2-OH 3.39Å; I135-I247 HydrophobicContact CG1-CD1 4.43Å
136	F	85.6	Confident	85.3	Confident	113 Å²	113	48.9 Å²	48.9	50%	0.496	25%	0.247	S	C	.	.	H	α-helix	trans	-66	-42.4	178.6	-70.1	-76.7	0	0	0	111.8	I58 G132 M133 S138 W139 I140	I58-F136 HydrophobicContact CG2-CE1 4.04Å; G132-F136 VanDerWaalsContact O-CD2 3.23Å; G132-F136 WeakPolarHBondContact O-CD2 3.38Å; M133-F136 PolarHBondContact O-N 3.35Å; F136-S138 VanDerWaalsContact C-N 3.31Å; F136-S138 PolarHBondContact O-N 3.28Å; F136-W139 PolarHBondContact O-N 3.27Å; F136-I140 WeakPolarHBondContact O-CG1 3.49Å; F136-I140 PolarHBondContact O-N 3.25Å
137	I	89.7	Confident	86.1	Confident	65 Å²	65	49.2 Å²	49.2	33%	0.333	25%	0.252	S	S	.	.	H	α-helix	trans	-60.1	-43.5	176.1	-65.4	168.8	0	0	0	110.5	M133 F134 W139 I140 L141 F250	M133-I137 WeakPolarHBondContact O-CG1 3.24Å; M133-I137 PolarHBondContact O-N 3.37Å; M133-I137 VanDerWaalsContact O-N 3.12Å; F134-I137 HydrophobicContact CD1-CD1 4.18Å; F134-I137 PolarHBondContact O-N 3.37Å; I137-W139 VanDerWaalsContact C-N 3.34Å; I137-W139 PolarHBondContact O-N 3.48Å; I137-I140 PolarHBondContact O-N 3.42Å; I137-L141 HydrophobicContact CG2-CD1 3.88Å; I137-L141 HydrophobicContact CG2-CG 4.29Å; I137-L141 WeakPolarHBondContact O-CG 3.36Å; I137-L141 PolarHBondContact O-N 3.45Å; I137-F250 HydrophobicContact CG2-CE2 4.19Å; I137-F250 HydrophobicContact CG2-CZ 4.17Å
138	S	91.7	Very high	86.8	Confident	0 Å²	0	53.7 Å²	53.7	0%	0	28%	0.275	C	S	.	.	H	α-helix	trans	-60.5	-42.5	177.8	-61.6	0	0	0	0	112	F134 I135 F136 T142 F250	F134-S138 VanDerWaalsContact O-CB 3.26Å; F134-S138 WeakPolarHBondContact O-CB 3.34Å; F134-S138 PolarHBondContact O-N 3.3Å; F134-S138 PolarHBondContact O-OG 3.06Å; I135-S138 PolarHBondContact O-N 2.83Å; F136-S138 VanDerWaalsContact C-N 3.31Å; F136-S138 PolarHBondContact O-N 3.28Å; S138-T142 VanDerWaalsContact O-CB 3.24Å; S138-T142 WeakPolarHBondContact O-CB 3.47Å; S138-T142 PolarHBondContact O-N 3.37Å; S138-T142 PolarHBondContact O-OG1 3.41Å; S138-F250 WeakPolarHBondContact OG-CD2 3.41Å; S138-F250 WeakPolarHBondContact OG-CE2 3.38Å
139	W	90.6	Very high	87.7	Confident	5 Å²	5	53.2 Å²	53.2	2%	0.019	27%	0.273	C	S	.	.	H	α-helix	trans	-64.2	-44.6	175.1	-85.5	116.9	0	0	0	112.5	V54 I58 I123 I135 F136 I137 L141 T142 I143 L239 Y243	V54-W139 HydrophobicContact CB-CH2 4.48Å; V54-W139 HydrophobicContact CB-CZ3 4.23Å; V54-W139 HydrophobicContact CG1-CD2 4.33Å; V54-W139 HydrophobicContact CG1-CE3 3.73Å; V54-W139 HydrophobicContact CG1-CH2 4.08Å; V54-W139 HydrophobicContact CG1-CZ3 3.61Å; V54-W139 HydrophobicContact CG2-CH2 4.14Å; V54-W139 HydrophobicContact CG2-CZ3 3.76Å; I58-W139 HydrophobicContact CD1-CD2 4.37Å; I58-W139 HydrophobicContact CD1-CG 4.17Å; I58-W139 HydrophobicContact CG1-CD2 4.25Å; I58-W139 HydrophobicContact CG1-CG 4.14Å; I123-W139 HydrophobicContact CD1-CH2 3.99Å; I123-W139 HydrophobicContact CD1-CZ2 4.09Å; I123-W139 HydrophobicContact CG2-CZ2 3.7Å; I135-W139 PolarHBondContact O-N 3Å; I135-W139 VanDerWaalsContact O-N 3.08Å; F136-W139 PolarHBondContact O-N 3.27Å; I137-W139 VanDerWaalsContact C-N 3.34Å; I137-W139 PolarHBondContact O-N 3.48Å; W139-L141 PolarHBondContact O-N 3.29Å; W139-T142 PolarHBondContact O-N 3.32Å; W139-I143 VanDerWaalsContact O-CG1 3.28Å; W139-I143 WeakPolarHBondContact O-CG1 3.32Å; W139-I143 PolarHBondContact O-N 3.22Å; W139-L239 HydrophobicContact CE3-CD2 4.27Å; W139-L239 HydrophobicContact CZ3-CD2 3.57Å; W139-Y243 AromaticContact CD1-CE2 3.43Å; W139-Y243 VanDerWaalsContact CD1-CE2 3.43Å; W139-Y243 AromaticContact CD2-CD2 3.73Å; W139-Y243 HydrophobicContact CD2-CD2 3.73Å; W139-Y243 AromaticContact CD2-CE2 3.91Å; W139-Y243 HydrophobicContact CD2-CE2 3.91Å; W139-Y243 HydrophobicContact CD2-CG 4.46Å; W139-Y243 AromaticContact CE2-CD2 3.84Å; W139-Y243 AromaticContact CE2-CE2 3.76Å; W139-Y243 HydrophobicContact CE3-CD2 4.18Å; W139-Y243 AromaticContact CG-CD2 3.94Å; W139-Y243 HydrophobicContact CG-CD2 3.94Å; W139-Y243 AromaticContact CG-CE2 3.77Å; W139-Y243 HydrophobicContact CG-CE2 3.77Å; W139-Y243 HydrophobicContact CZ2-CD2 4.44Å; W139-Y243 AromaticContact NE1-CD2 3.97Å; W139-Y243 AromaticContact NE1-CE2 3.4Å; W139-Y243 AromaticContact NE1-CZ 3.7Å
140	I	91.8	Very high	88.7	Confident	99 Å²	99	49.2 Å²	49.2	51%	0.508	26%	0.257	S	S	.	.	H	α-helix	trans	-59.7	-49.4	177.6	-68.7	167.1	0	0	0	110.3	F136 I137 T142 I143 I144	F136-I140 WeakPolarHBondContact O-CG1 3.49Å; F136-I140 PolarHBondContact O-N 3.25Å; I137-I140 PolarHBondContact O-N 3.42Å; I140-T142 VanDerWaalsContact C-N 3.32Å; I140-T142 PolarHBondContact O-N 2.92Å; I140-I143 PolarHBondContact O-N 2.68Å; I140-I144 HydrophobicContact CG2-CD1 3.73Å; I140-I144 VanDerWaalsContact O-CG1 3.31Å; I140-I144 WeakPolarHBondContact O-CG1 3.45Å; I140-I144 PolarHBondContact O-N 2.94Å
141	L	94.5	Very high	89.5	Confident	62 Å²	62	52.9 Å²	52.9	33%	0.325	28%	0.276	S	S	.	.	H	α-helix	trans	-61.4	-41.2	178.6	-70.6	173.9	0	0	0	112	I137 W139 I144 L145 F246 F250	I137-L141 HydrophobicContact CG2-CD1 3.88Å; I137-L141 HydrophobicContact CG2-CG 4.29Å; I137-L141 WeakPolarHBondContact O-CG 3.36Å; I137-L141 PolarHBondContact O-N 3.45Å; W139-L141 PolarHBondContact O-N 3.29Å; L141-I144 PolarHBondContact O-N 2.94Å; L141-L145 VanDerWaalsContact O-CB 3.24Å; L141-L145 WeakPolarHBondContact O-CB 3.48Å; L141-L145 PolarHBondContact O-N 2.94Å; L141-F246 HydrophobicContact CB-CD1 4.22Å; L141-F246 HydrophobicContact CB-CD2 4.12Å; L141-F246 HydrophobicContact CB-CE1 3.97Å; L141-F246 HydrophobicContact CB-CE2 3.85Å; L141-F246 HydrophobicContact CB-CG 4.29Å; L141-F246 HydrophobicContact CB-CZ 3.78Å; L141-F246 HydrophobicContact CD1-CD1 3.9Å; L141-F246 HydrophobicContact CD1-CE1 3.99Å; L141-F246 HydrophobicContact CD1-CG 4.49Å; L141-F250 HydrophobicContact CD1-CE2 4.18Å; L141-F250 HydrophobicContact CD1-CZ 3.86Å
142	T	94.1	Very high	90.5	Very high	0 Å²	0	53 Å²	53	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-61.8	-44.9	177.2	-63.6	0	0	0	0	112.2	S138 W139 I140 L145 S146 L239 Y243 F246	S138-T142 VanDerWaalsContact O-CB 3.24Å; S138-T142 WeakPolarHBondContact O-CB 3.47Å; S138-T142 PolarHBondContact O-N 3.37Å; S138-T142 PolarHBondContact O-OG1 3.41Å; W139-T142 PolarHBondContact O-N 3.32Å; I140-T142 VanDerWaalsContact C-N 3.32Å; I140-T142 PolarHBondContact O-N 2.92Å; T142-L145 PolarHBondContact O-N 3.34Å; T142-S146 WeakPolarHBondContact O-CB 3.4Å; T142-S146 PolarHBondContact O-N 3.14Å; T142-L239 HydrophobicContact CG2-CD2 3.56Å; T142-L239 HydrophobicContact CG2-CG 3.75Å; T142-L239 WeakPolarHBondContact CG2-O 3.28Å; T142-Y243 VanDerWaalsContact OG1-CA 3.26Å; T142-Y243 WeakPolarHBondContact OG1-CA 3.38Å; T142-Y243 PolarHBondContact OG1-N 3.26Å; T142-F246 WeakPolarHBondContact OG1-CD2 3.36Å
143	I	92.4	Very high	91.2	Very high	73 Å²	73	51.4 Å²	51.4	37%	0.374	27%	0.266	S	S	.	.	H	α-helix	trans	-65.9	-46.3	179.2	-68	163.9	0	0	0	110.3	V54 W139 I140 L145 S146 V147	V54-I143 HydrophobicContact CG1-CD1 4.4Å; W139-I143 VanDerWaalsContact O-CG1 3.28Å; W139-I143 WeakPolarHBondContact O-CG1 3.32Å; W139-I143 PolarHBondContact O-N 3.22Å; I140-I143 PolarHBondContact O-N 2.68Å; I143-L145 VanDerWaalsContact C-N 3.34Å; I143-L145 PolarHBondContact O-N 2.69Å; I143-S146 PolarHBondContact O-N 3.48Å; I143-V147 WeakPolarHBondContact O-CG2 3.42Å; I143-V147 PolarHBondContact O-N 3.41Å
144	I	94.6	Very high	91.4	Very high	89 Å²	89	47.6 Å²	47.6	46%	0.456	25%	0.248	S	C	.	.	H	α-helix	trans	-59.3	-47.4	177.5	-69	169.5	0	0	0	110.2	I140 L141 V147 L148	I140-I144 HydrophobicContact CG2-CD1 3.73Å; I140-I144 VanDerWaalsContact O-CG1 3.31Å; I140-I144 WeakPolarHBondContact O-CG1 3.45Å; I140-I144 PolarHBondContact O-N 2.94Å; L141-I144 PolarHBondContact O-N 2.94Å; I144-V147 PolarHBondContact O-N 3.46Å; I144-L148 HydrophobicContact CG2-CD1 3.72Å; I144-L148 HydrophobicContact CG2-CG 4.41Å; I144-L148 WeakPolarHBondContact O-CB 3.44Å; I144-L148 WeakPolarHBondContact O-CG 3.47Å; I144-L148 PolarHBondContact O-N 3.22Å
145	L	95.4	Very high	91.5	Very high	38 Å²	38	52.5 Å²	52.5	20%	0.199	28%	0.275	C	S	.	.	H	α-helix	trans	-62.2	-45.1	179.1	-176.3	63.3	0	0	0	111.4	L141 T142 I143 V147 L148 L149 L201 F246	L141-L145 VanDerWaalsContact O-CB 3.24Å; L141-L145 WeakPolarHBondContact O-CB 3.48Å; L141-L145 PolarHBondContact O-N 2.94Å; T142-L145 PolarHBondContact O-N 3.34Å; I143-L145 VanDerWaalsContact C-N 3.34Å; I143-L145 PolarHBondContact O-N 2.69Å; L145-V147 PolarHBondContact O-N 3.32Å; L145-L148 PolarHBondContact O-N 3.48Å; L145-L149 HydrophobicContact CD1-CD1 3.91Å; L145-L149 HydrophobicContact CD1-CD2 4.49Å; L145-L149 HydrophobicContact CD1-CG 3.98Å; L145-L149 HydrophobicContact CD2-CD1 4.38Å; L145-L149 HydrophobicContact CG-CD1 3.74Å; L145-L149 HydrophobicContact CG-CG 4.22Å; L145-L149 WeakPolarHBondContact O-CB 3.33Å; L145-L149 VanDerWaalsContact O-CG 3.23Å; L145-L149 WeakPolarHBondContact O-CG 3.49Å; L145-L149 PolarHBondContact O-N 3.43Å; L145-L201 HydrophobicContact CD2-CD2 4.13Å; L145-F246 HydrophobicContact CD2-CE2 4.1Å; L145-F246 HydrophobicContact CD2-CZ 4.06Å
146	S	93.8	Very high	91.5	Very high	14 Å²	14	54.7 Å²	54.7	10%	0.098	29%	0.286	C	S	.	.	H	α-helix	trans	-59.4	-47.5	178.3	178.1	0	0	0	0	112.1	T142 I143 L149 F150 H235	T142-S146 WeakPolarHBondContact O-CB 3.4Å; T142-S146 PolarHBondContact O-N 3.14Å; I143-S146 PolarHBondContact O-N 3.48Å; S146-L149 PolarHBondContact O-N 3.27Å; S146-F150 WeakPolarHBondContact O-CB 3.39Å; S146-F150 PolarHBondContact O-N 3.35Å; S146-H235 PolarHBondContact OG-CE1 2.96Å; S146-H235 PolarHBondContact OG-NE2 2.89Å
147	V	93.2	Very high	91.2	Very high	68 Å²	68	55.9 Å²	55.9	41%	0.412	29%	0.293	S	S	.	.	H	α-helix	trans	-64.2	-44	178.8	173.8	0	0	0	0	111.2	I143 I144 L145 F150 L151	I143-V147 WeakPolarHBondContact O-CG2 3.42Å; I143-V147 PolarHBondContact O-N 3.41Å; I144-V147 PolarHBondContact O-N 3.46Å; L145-V147 PolarHBondContact O-N 3.32Å; V147-F150 PolarHBondContact O-N 2.83Å; V147-L151 HydrophobicContact CG1-CD1 4.08Å; V147-L151 HydrophobicContact CG1-CG 4.49Å; V147-L151 WeakPolarHBondContact O-CG 3.29Å; V147-L151 PolarHBondContact O-N 3.43Å
148	L	95.3	Very high	90.8	Very high	94 Å²	94	61.7 Å²	61.7	49%	0.492	31%	0.311	S	S	.	.	H	α-helix	trans	-61.5	-48.6	177.4	-77.5	170.1	0	0	0	111.6	I144 L145 F150 L151 V152	I144-L148 HydrophobicContact CG2-CD1 3.72Å; I144-L148 HydrophobicContact CG2-CG 4.41Å; I144-L148 WeakPolarHBondContact O-CB 3.44Å; I144-L148 WeakPolarHBondContact O-CG 3.47Å; I144-L148 PolarHBondContact O-N 3.22Å; L145-L148 PolarHBondContact O-N 3.48Å; L148-F150 VanDerWaalsContact C-N 3.28Å; L148-F150 PolarHBondContact O-N 2.94Å; L148-L151 PolarHBondContact O-N 3.08Å; L148-V152 WeakPolarHBondContact O-CB 3.43Å; L148-V152 VanDerWaalsContact O-CG2 3.28Å; L148-V152 WeakPolarHBondContact O-CG2 3.47Å; L148-V152 PolarHBondContact O-N 3.47Å
149	L	94.6	Very high	90.3	Very high	18 Å²	18	62.9 Å²	62.9	9%	0.094	32%	0.317	C	S	.	.	H	α-helix	trans	-62.8	-37.1	178.4	-69.2	174.4	0	0	0	111.3	L145 S146 G153 I205 L209	L145-L149 HydrophobicContact CD1-CD1 3.91Å; L145-L149 HydrophobicContact CD1-CD2 4.49Å; L145-L149 HydrophobicContact CD1-CG 3.98Å; L145-L149 HydrophobicContact CD2-CD1 4.38Å; L145-L149 HydrophobicContact CG-CD1 3.74Å; L145-L149 HydrophobicContact CG-CG 4.22Å; L145-L149 WeakPolarHBondContact O-CB 3.33Å; L145-L149 VanDerWaalsContact O-CG 3.23Å; L145-L149 WeakPolarHBondContact O-CG 3.49Å; L145-L149 PolarHBondContact O-N 3.43Å; S146-L149 PolarHBondContact O-N 3.27Å; L149-G153 PolarHBondContact O-N 3.38Å; L149-I205 HydrophobicContact CD1-CG1 4.23Å; L149-I205 HydrophobicContact CD2-CB 4.43Å; L149-I205 HydrophobicContact CD2-CG1 4.39Å; L149-I205 HydrophobicContact CD2-CG2 3.91Å; L149-L209 HydrophobicContact CD2-CD2 4.23Å; L149-L209 HydrophobicContact CD2-CG 4.29Å; L149-L209 WeakPolarHBondContact O-CD2 3.43Å
150	F	92	Very high	89.9	Confident	22 Å²	22	64.6 Å²	64.6	10%	0.096	33%	0.326	C	S	.	.	H	α-helix	trans	-63	-49.3	175.1	-169.1	-96	0	0	0	111.9	I43 F47 S146 V147 L148 V152 G153 I154 A212 L215	I43-F150 HydrophobicContact CD1-CZ 4.38Å; I43-F150 HydrophobicContact CG2-CE1 4.02Å; I43-F150 HydrophobicContact CG2-CZ 3.63Å; F47-F150 HydrophobicContact CE2-CD1 4.03Å; F47-F150 AromaticContact CE2-CD2 3.9Å; F47-F150 HydrophobicContact CE2-CD2 3.9Å; F47-F150 AromaticContact CE2-CE1 3.93Å; F47-F150 HydrophobicContact CE2-CE1 3.93Å; F47-F150 AromaticContact CE2-CE2 3.8Å; F47-F150 HydrophobicContact CE2-CE2 3.8Å; F47-F150 HydrophobicContact CE2-CG 4.02Å; F47-F150 AromaticContact CE2-CZ 3.83Å; F47-F150 HydrophobicContact CE2-CZ 3.83Å; F47-F150 HydrophobicContact CZ-CB 4.15Å; F47-F150 HydrophobicContact CZ-CD1 4.01Å; F47-F150 AromaticContact CZ-CD2 3.76Å; F47-F150 HydrophobicContact CZ-CD2 3.76Å; F47-F150 HydrophobicContact CZ-CE1 4.38Å; F47-F150 HydrophobicContact CZ-CE2 4.16Å; F47-F150 AromaticContact CZ-CG 3.68Å; F47-F150 HydrophobicContact CZ-CG 3.68Å; F47-F150 HydrophobicContact CZ-CZ 4.46Å; S146-F150 WeakPolarHBondContact O-CB 3.39Å; S146-F150 PolarHBondContact O-N 3.35Å; V147-F150 PolarHBondContact O-N 2.83Å; L148-F150 VanDerWaalsContact C-N 3.28Å; L148-F150 PolarHBondContact O-N 2.94Å; F150-V152 PolarHBondContact O-N 3.12Å; F150-G153 PolarHBondContact O-N 2.91Å; F150-I154 HydrophobicContact CD1-CG2 4.42Å; F150-I154 HydrophobicContact CE1-CG2 4.05Å; F150-I154 HydrophobicContact CZ-CG2 4.18Å; F150-I154 WeakPolarHBondContact O-CG2 3.47Å; F150-I154 PolarHBondContact O-N 2.89Å; F150-I154 VanDerWaalsContact O-N 3.08Å; F150-A212 HydrophobicContact CD2-CB 3.61Å; F150-A212 HydrophobicContact CE2-CB 4.03Å; F150-A212 HydrophobicContact CG-CB 4.23Å; F150-L215 HydrophobicContact CD2-CD1 4.35Å; F150-L215 HydrophobicContact CE2-CB 3.92Å; F150-L215 HydrophobicContact CE2-CD1 3.69Å; F150-L215 HydrophobicContact CE2-CG 4.46Å; F150-L215 HydrophobicContact CZ-CB 4.4Å
151	L	91.6	Very high	89.3	Confident	89 Å²	89	60 Å²	60	47%	0.466	30%	0.303	S	S	.	.	H	α-helix	trans	-63.6	-39.2	178.6	-69.9	173.8	0	0	0	112.9	V147 L148 I154 N155	V147-L151 HydrophobicContact CG1-CD1 4.08Å; V147-L151 HydrophobicContact CG1-CG 4.49Å; V147-L151 WeakPolarHBondContact O-CG 3.29Å; V147-L151 PolarHBondContact O-N 3.43Å; L148-L151 PolarHBondContact O-N 3.08Å; L151-I154 HydrophobicContact CD2-CD1 4.26Å; L151-I154 WeakPolarHBondContact O-CG1 3.43Å; L151-N155 PolarHBondContact O-N 3.06Å; L151-N155 PolarHBondContact O-ND2 2.83Å
152	V	92.8	Very high	88.7	Confident	77 Å²	77	59.9 Å²	59.9	47%	0.467	31%	0.307	S	S	.	.	H	α-helix	trans	-67.2	-45.9	175	172.4	0	0	0	0	109.9	L148 F150 I154 N155 I156 L209	L148-V152 WeakPolarHBondContact O-CB 3.43Å; L148-V152 VanDerWaalsContact O-CG2 3.28Å; L148-V152 WeakPolarHBondContact O-CG2 3.47Å; L148-V152 PolarHBondContact O-N 3.47Å; F150-V152 PolarHBondContact O-N 3.12Å; V152-I154 PolarHBondContact O-N 3.31Å; V152-N155 PolarHBondContact O-N 3.22Å; V152-N155 VanDerWaalsContact O-N 3.07Å; V152-I156 HydrophobicContact CG1-CD1 4.06Å; V152-I156 HydrophobicContact CG1-CG1 4.38Å; V152-I156 WeakPolarHBondContact O-CG1 3.26Å; V152-I156 PolarHBondContact O-N 2.87Å; V152-I156 VanDerWaalsContact O-N 3.12Å; V152-L209 HydrophobicContact CB-CD2 4.11Å; V152-L209 HydrophobicContact CG1-CD2 3.85Å
153	G	87.8	Confident	88.2	Confident	0 Å²	0	65.7 Å²	65.7	0%	0	33%	0.33	C	S	.	.	H	α-helix	trans	-58.7	-42.3	-178.1	0	0	0	0	0	113.5	L149 F150 N155 I156 Q213	L149-G153 PolarHBondContact O-N 3.38Å; F150-G153 PolarHBondContact O-N 2.91Å; G153-N155 VanDerWaalsContact C-N 3.29Å; G153-N155 PolarHBondContact O-N 2.96Å; G153-I156 PolarHBondContact O-N 2.78Å; G153-Q213 VanDerWaalsContact O-CG 3.26Å; G153-Q213 WeakPolarHBondContact O-CG 3.07Å; G153-Q213 PolarHBondContact O-NE2 3.48Å
154	I	87.4	Confident	87.6	Confident	44 Å²	44	66.5 Å²	66.5	23%	0.226	33%	0.331	C	S	.	.	H	α-helix	trans	-69	-26.2	177.2	64.8	174.4	0	0	0	113.3	F150 L151 V152 Y216	F150-I154 HydrophobicContact CD1-CG2 4.42Å; F150-I154 HydrophobicContact CE1-CG2 4.05Å; F150-I154 HydrophobicContact CZ-CG2 4.18Å; F150-I154 WeakPolarHBondContact O-CG2 3.47Å; F150-I154 PolarHBondContact O-N 2.89Å; F150-I154 VanDerWaalsContact O-N 3.08Å; L151-I154 HydrophobicContact CD2-CD1 4.26Å; L151-I154 WeakPolarHBondContact O-CG1 3.43Å; V152-I154 PolarHBondContact O-N 3.31Å; I154-Y216 HydrophobicContact CB-CD2 4.16Å; I154-Y216 HydrophobicContact CB-CG 4.34Å; I154-Y216 HydrophobicContact CG2-CD2 3.86Å; I154-Y216 HydrophobicContact CG2-CG 4Å
155	N	86.9	Confident	87.1	Confident	123 Å²	123	71.1 Å²	71.1	66%	0.658	34%	0.343	S	S	*	.	H	α-helix	trans	-87.3	-17.2	-178.8	-78.3	-24	0	0	0	113.2	L151 V152 G153 E157	L151-N155 PolarHBondContact O-N 3.06Å; L151-N155 PolarHBondContact O-ND2 2.83Å; V152-N155 PolarHBondContact O-N 3.22Å; V152-N155 VanDerWaalsContact O-N 3.07Å; G153-N155 VanDerWaalsContact C-N 3.29Å; G153-N155 PolarHBondContact O-N 2.96Å; N155-E157 PolarHBondContact O-N 2.84Å
156	I	85.2	Confident	86.7	Confident	56 Å²	56	77.1 Å²	77.1	29%	0.287	36%	0.363	S	S	.	.			trans	-66.7	122.1	176.9	-69.9	167	0	0	0	109.6	V152 G153 R158 L160 L209 Q213	V152-I156 HydrophobicContact CG1-CD1 4.06Å; V152-I156 HydrophobicContact CG1-CG1 4.38Å; V152-I156 WeakPolarHBondContact O-CG1 3.26Å; V152-I156 PolarHBondContact O-N 2.87Å; V152-I156 VanDerWaalsContact O-N 3.12Å; G153-I156 PolarHBondContact O-N 2.78Å; I156-R158 HydrophobicContact CG2-CB 4.23Å; I156-R158 WeakPolarHBondContact CG2-O 3.2Å; I156-L160 HydrophobicContact CD1-CD1 3.93Å; I156-L160 HydrophobicContact CG2-CD1 4.36Å; I156-L160 HydrophobicContact CG2-CD2 4.42Å; I156-L160 HydrophobicContact CG2-CG 4.24Å; I156-L209 HydrophobicContact CD1-CD2 4.15Å; I156-Q213 PolarHBondContact O-NE2 3.43Å
157	E	80	Confident	86.5	Confident	137 Å²	137	77.5 Å²	77.5	64%	0.64	36%	0.363	S	S	*	.			trans	-75.9	-26.5	-177.2	-48.7	-148.5	115.3	0	0	114.3	K30 N155	K30-E157 IonicContact NZ-OE1 3.83Å; K30-E157 PolarHBondContact NZ-OE1 3.26Å; N155-E157 PolarHBondContact O-N 2.84Å
158	R	80.8	Confident	86.2	Confident	188 Å²	188	78.8 Å²	78.8	71%	0.709	37%	0.365	S	S	*	.	S	Bend	trans	-76.4	141.9	177.5	-79.8	-178.8	176	164.9	-0.6	110.1	I156 L160 Q213	I156-R158 HydrophobicContact CG2-CB 4.23Å; I156-R158 WeakPolarHBondContact CG2-O 3.2Å; R158-L160 PolarHBondContact O-N 2.89Å; R158-L160 VanDerWaalsContact O-N 3.14Å; R158-Q213 PolarHBondContact O-NE2 3.4Å
159	D	81	Confident	86.1	Confident	24 Å²	24	78.7 Å²	78.7	13%	0.128	36%	0.364	C	S	.	.			trans	-77	99.5	173.9	-169.5	11.3	0	0	0	110.3	V161 S162 E220	D159-V161 PolarHBondContact O-N 2.89Å; D159-V161 VanDerWaalsContact OD1-CB 3.24Å; D159-V161 WeakPolarHBondContact OD1-CB 3.41Å; D159-V161 WeakPolarHBondContact OD1-CG2 3.43Å; D159-V161 PolarHBondContact OD1-N 3.14Å; D159-S162 PolarHBondContact O-N 3.36Å; D159-S162 PolarHBondContact O-OG 2.9Å; D159-E220 PolarHBondContact OD2-N 2.96Å
160	L	82.9	Confident	86	Confident	41 Å²	41	82.5 Å²	82.5	22%	0.215	38%	0.378	C	S	.	.	G	3₁₀ helix	trans	-68.2	-24.9	178.6	-62.4	170.6	0	0	0	111.4	I156 R158 S162 Y163 L209 I210 Q213	I156-L160 HydrophobicContact CD1-CD1 3.93Å; I156-L160 HydrophobicContact CG2-CD1 4.36Å; I156-L160 HydrophobicContact CG2-CD2 4.42Å; I156-L160 HydrophobicContact CG2-CG 4.24Å; R158-L160 PolarHBondContact O-N 2.89Å; R158-L160 VanDerWaalsContact O-N 3.14Å; L160-S162 PolarHBondContact O-N 3.45Å; L160-Y163 PolarHBondContact O-N 3.43Å; L160-Y163 VanDerWaalsContact O-N 3.08Å; L160-L209 HydrophobicContact CD1-CB 3.78Å; L160-I210 HydrophobicContact CB-CG1 3.88Å; L160-Q213 VanDerWaalsContact CB-OE1 3.24Å
161	V	79.5	Confident	86	Confident	2 Å²	2	82.8 Å²	82.8	1%	0.012	38%	0.381	C	S	.	.	G	3₁₀ helix	trans	-60.5	-36.6	178.7	-177.4	0	0	0	0	111.1	D159 Y163 F164 I210 I214 E220 I221	D159-V161 PolarHBondContact O-N 2.89Å; D159-V161 VanDerWaalsContact OD1-CB 3.24Å; D159-V161 WeakPolarHBondContact OD1-CB 3.41Å; D159-V161 WeakPolarHBondContact OD1-CG2 3.43Å; D159-V161 PolarHBondContact OD1-N 3.14Å; V161-Y163 PolarHBondContact O-N 3.06Å; V161-Y163 VanDerWaalsContact O-N 3.1Å; V161-F164 WeakPolarHBondContact O-CB 3.14Å; V161-F164 PolarHBondContact O-N 3.2Å; V161-I210 HydrophobicContact CG2-CG2 4.46Å; V161-I214 HydrophobicContact CG2-CG1 3.96Å; V161-E220 HydrophobicContact CG1-CB 4.09Å; V161-I221 HydrophobicContact CG1-CB 3.55Å; V161-I221 HydrophobicContact CG1-CD1 3.4Å; V161-I221 VanDerWaalsContact CG1-CD1 3.4Å; V161-I221 HydrophobicContact CG1-CG1 3.51Å
162	S	81.4	Confident	86	Confident	60 Å²	60	81.4 Å²	81.4	42%	0.42	38%	0.382	S	S	.	.	G	3₁₀ helix	trans	-59.8	-25	178	69	0	0	0	0	113.3	D159 L160 F164	D159-S162 PolarHBondContact O-N 3.36Å; D159-S162 PolarHBondContact O-OG 2.9Å; L160-S162 PolarHBondContact O-N 3.45Å; S162-F164 VanDerWaalsContact C-N 3.33Å
163	Y	82.6	Confident	86.1	Confident	123 Å²	123	80.5 Å²	80.5	48%	0.482	38%	0.379	S	S	.	.	G	3₁₀ helix	trans	-91.2	9.6	178.3	-60.3	-83.8	0	0	0	113.3	L160 V161 R165 W166 F167	L160-Y163 PolarHBondContact O-N 3.43Å; L160-Y163 VanDerWaalsContact O-N 3.08Å; V161-Y163 PolarHBondContact O-N 3.06Å; V161-Y163 VanDerWaalsContact O-N 3.1Å; Y163-R165 PolarHBondContact O-N 3.39Å; Y163-R165 VanDerWaalsContact O-N 3.08Å; Y163-W166 PolarHBondContact O-N 2.89Å; Y163-F167 PolarHBondContact O-N 3.46Å
164	F	81	Confident	86.3	Confident	89 Å²	89	81.1 Å²	81.1	39%	0.39	38%	0.382	S	S	.	.	H	α-helix	trans	-52.4	-38.4	-175.9	-172.5	-99	0	0	0	113	V161 S162 F167 M168	V161-F164 WeakPolarHBondContact O-CB 3.14Å; V161-F164 PolarHBondContact O-N 3.2Å; S162-F164 VanDerWaalsContact C-N 3.33Å; F164-F167 WeakPolarHBondContact O-CB 3.33Å; F164-F167 PolarHBondContact O-N 2.93Å; F164-M168 HydrophobicContact CD1-CG 4.14Å; F164-M168 HydrophobicContact CE1-CG 3.79Å; F164-M168 HydrophobicContact CE1-SD 4.02Å; F164-M168 HydrophobicContact CE2-SD 4.47Å; F164-M168 HydrophobicContact CZ-CG 4.17Å; F164-M168 HydrophobicContact CZ-SD 3.82Å; F164-M168 WeakPolarHBondContact O-CG 3.4Å; F164-M168 PolarHBondContact O-N 3.17Å
165	R	84.1	Confident	86.5	Confident	187 Å²	187	82.8 Å²	82.8	71%	0.706	39%	0.391	S	S	*	.	H	α-helix	trans	-64.8	-42.6	177.8	-160.9	179.2	85.8	-174.9	6.2	112.8	Y163 F167 M168 I169	Y163-R165 PolarHBondContact O-N 3.39Å; Y163-R165 VanDerWaalsContact O-N 3.08Å; R165-F167 VanDerWaalsContact C-N 3.3Å; R165-M168 PolarHBondContact O-N 2.99Å; R165-I169 PolarHBondContact O-N 3.02Å
166	W	87.7	Confident	86.8	Confident	164 Å²	164	81.9 Å²	81.9	62%	0.621	39%	0.385	S	S	*	.	H	α-helix	trans	-67.1	-36.4	175.4	-71.5	110	0	0	0	111.3	Y163 M168 I169 Y170	Y163-W166 PolarHBondContact O-N 2.89Å; W166-M168 PolarHBondContact O-N 3.5Å; W166-I169 HydrophobicContact CE3-CD1 4.04Å; W166-I169 HydrophobicContact CZ3-CD1 4.28Å; W166-I169 PolarHBondContact O-N 2.83Å; W166-Y170 PolarHBondContact O-N 3.2Å
167	F	88.1	Confident	87.1	Confident	22 Å²	22	82.5 Å²	82.5	10%	0.096	39%	0.391	C	S	.	.	H	α-helix	trans	-61.5	-41.8	174.2	-179	-122.7	0	0	0	112.3	Y163 F164 R165 I169 Y170 I171 P206 A207 I210	Y163-F167 PolarHBondContact O-N 3.46Å; F164-F167 WeakPolarHBondContact O-CB 3.33Å; F164-F167 PolarHBondContact O-N 2.93Å; R165-F167 VanDerWaalsContact C-N 3.3Å; F167-I169 VanDerWaalsContact C-N 3.32Å; F167-I169 PolarHBondContact O-N 3.3Å; F167-Y170 HydrophobicContact CD2-CD1 4.08Å; F167-Y170 AromaticContact CE2-CD1 3.97Å; F167-Y170 HydrophobicContact CE2-CD1 3.97Å; F167-Y170 HydrophobicContact CE2-CE1 4.46Å; F167-Y170 WeakPolarHBondContact O-CB 3.22Å; F167-Y170 PolarHBondContact O-N 2.86Å; F167-I171 HydrophobicContact CD1-CD1 3.73Å; F167-I171 HydrophobicContact CD1-CG1 4.48Å; F167-I171 HydrophobicContact CD2-CD1 4.32Å; F167-I171 HydrophobicContact CD2-CG1 4.21Å; F167-I171 HydrophobicContact CE1-CD1 3.2Å; F167-I171 HydrophobicContact CE1-CG1 4.03Å; F167-I171 HydrophobicContact CE2-CD1 3.79Å; F167-I171 HydrophobicContact CE2-CG1 3.62Å; F167-I171 HydrophobicContact CG-CD1 4.27Å; F167-I171 HydrophobicContact CZ-CD1 3.22Å; F167-I171 HydrophobicContact CZ-CG1 3.55Å; F167-I171 WeakPolarHBondContact O-CG1 3.38Å; F167-I171 PolarHBondContact O-N 3.41Å; F167-P206 HydrophobicContact CD2-CB 3.87Å; F167-P206 HydrophobicContact CD2-CG 4.13Å; F167-P206 HydrophobicContact CE2-CB 3.44Å; F167-P206 VanDerWaalsContact CE2-CB 3.44Å; F167-P206 HydrophobicContact CE2-CG 3.32Å; F167-P206 HydrophobicContact CZ-CB 4.1Å; F167-P206 HydrophobicContact CZ-CG 4Å; F167-A207 HydrophobicContact CE1-CB 4.03Å; F167-A207 HydrophobicContact CZ-CB 3.73Å; F167-I210 HydrophobicContact CB-CD1 4.12Å; F167-I210 HydrophobicContact CD1-CD1 3.46Å; F167-I210 VanDerWaalsContact CD1-CD1 3.46Å; F167-I210 HydrophobicContact CD2-CD1 4.38Å; F167-I210 HydrophobicContact CE1-CD1 3.94Å; F167-I210 HydrophobicContact CG-CD1 3.7Å
168	M	88.4	Confident	87.6	Confident	95 Å²	95	77.4 Å²	77.4	47%	0.468	37%	0.368	S	S	.	.	H	α-helix	trans	-62.2	-38.2	175.3	-68	-57.7	-66	0	0	112.8	F164 R165 W166 I171 A172	F164-M168 HydrophobicContact CD1-CG 4.14Å; F164-M168 HydrophobicContact CE1-CG 3.79Å; F164-M168 HydrophobicContact CE1-SD 4.02Å; F164-M168 HydrophobicContact CE2-SD 4.47Å; F164-M168 HydrophobicContact CZ-CG 4.17Å; F164-M168 HydrophobicContact CZ-SD 3.82Å; F164-M168 WeakPolarHBondContact O-CG 3.4Å; F164-M168 PolarHBondContact O-N 3.17Å; R165-M168 PolarHBondContact O-N 2.99Å; W166-M168 PolarHBondContact O-N 3.5Å; M168-I171 PolarHBondContact O-N 2.97Å; M168-I171 HydrophobicContact SD-CD1 4.22Å; M168-A172 WeakPolarHBondContact O-CB 3.32Å; M168-A172 PolarHBondContact O-N 2.9Å
169	I	92	Very high	88.1	Confident	92 Å²	92	73.2 Å²	73.2	47%	0.472	36%	0.359	S	S	.	.	H	α-helix	trans	-65.2	-43.1	175	-63.4	167.8	0	0	0	110.3	R165 W166 F167 A172 S173	R165-I169 PolarHBondContact O-N 3.02Å; W166-I169 HydrophobicContact CE3-CD1 4.04Å; W166-I169 HydrophobicContact CZ3-CD1 4.28Å; W166-I169 PolarHBondContact O-N 2.83Å; F167-I169 VanDerWaalsContact C-N 3.32Å; F167-I169 PolarHBondContact O-N 3.3Å; I169-A172 PolarHBondContact O-N 2.97Å; I169-S173 PolarHBondContact O-N 3.07Å
170	Y	92.6	Very high	88.6	Confident	98 Å²	98	76.9 Å²	76.9	38%	0.384	38%	0.378	S	S	.	.	H	α-helix	trans	-59.6	-48.4	176	171.4	-100	0	0	0	111.9	W166 F167 A172 S173 I174 A202 P206	W166-Y170 PolarHBondContact O-N 3.2Å; F167-Y170 HydrophobicContact CD2-CD1 4.08Å; F167-Y170 AromaticContact CE2-CD1 3.97Å; F167-Y170 HydrophobicContact CE2-CD1 3.97Å; F167-Y170 HydrophobicContact CE2-CE1 4.46Å; F167-Y170 WeakPolarHBondContact O-CB 3.22Å; F167-Y170 PolarHBondContact O-N 2.86Å; Y170-A172 VanDerWaalsContact C-N 3.35Å; Y170-A172 PolarHBondContact O-N 3.08Å; Y170-S173 PolarHBondContact O-N 3.38Å; Y170-S173 PolarHBondContact O-OG 3.06Å; Y170-I174 HydrophobicContact CD1-CD1 4.22Å; Y170-I174 HydrophobicContact CD2-CD1 4.45Å; Y170-I174 HydrophobicContact CE1-CD1 3.5Å; Y170-I174 VanDerWaalsContact CE1-CD1 3.5Å; Y170-I174 HydrophobicContact CE2-CD1 3.76Å; Y170-I174 HydrophobicContact CE2-CG1 4.37Å; Y170-I174 PolarHBondContact O-N 3.29Å; Y170-I174 VanDerWaalsContact OH-CD1 3.32Å; Y170-I174 WeakPolarHBondContact OH-CD1 3.24Å; Y170-A202 PolarHBondContact OH-O 3.35Å; Y170-P206 HydrophobicContact CD1-CG 4.46Å; Y170-P206 HydrophobicContact CE1-CG 3.91Å
171	I	91.1	Very high	88.9	Confident	28 Å²	28	76.7 Å²	76.7	14%	0.144	38%	0.377	C	S	.	.	H	α-helix	trans	-58.5	-47.7	176.4	-64	167.2	0	0	0	110.7	F167 M168 S173 I174 I175 I203	F167-I171 HydrophobicContact CD1-CD1 3.73Å; F167-I171 HydrophobicContact CD1-CG1 4.48Å; F167-I171 HydrophobicContact CD2-CD1 4.32Å; F167-I171 HydrophobicContact CD2-CG1 4.21Å; F167-I171 HydrophobicContact CE1-CD1 3.2Å; F167-I171 HydrophobicContact CE1-CG1 4.03Å; F167-I171 HydrophobicContact CE2-CD1 3.79Å; F167-I171 HydrophobicContact CE2-CG1 3.62Å; F167-I171 HydrophobicContact CG-CD1 4.27Å; F167-I171 HydrophobicContact CZ-CD1 3.22Å; F167-I171 HydrophobicContact CZ-CG1 3.55Å; F167-I171 WeakPolarHBondContact O-CG1 3.38Å; F167-I171 PolarHBondContact O-N 3.41Å; M168-I171 PolarHBondContact O-N 2.97Å; M168-I171 HydrophobicContact SD-CD1 4.22Å; I171-S173 VanDerWaalsContact C-N 3.25Å; I171-S173 PolarHBondContact O-N 2.96Å; I171-I174 PolarHBondContact O-N 2.92Å; I171-I175 HydrophobicContact CG2-CD1 3.64Å; I171-I175 HydrophobicContact CG2-CG1 4.21Å; I171-I175 WeakPolarHBondContact O-CG1 3.22Å; I171-I175 PolarHBondContact O-N 3.26Å; I171-I203 HydrophobicContact CG1-CG2 4.23Å; I171-I203 HydrophobicContact CG2-CG2 4.18Å
172	A	92.7	Very high	89.1	Confident	59 Å²	59	80 Å²	80	49%	0.488	39%	0.394	S	S	.	.	H	α-helix	trans	-59	-38.9	179.4	0	0	0	0	0	111.9	M168 I169 Y170 I175 L176	M168-A172 WeakPolarHBondContact O-CB 3.32Å; M168-A172 PolarHBondContact O-N 2.9Å; I169-A172 PolarHBondContact O-N 2.97Å; Y170-A172 VanDerWaalsContact C-N 3.35Å; Y170-A172 PolarHBondContact O-N 3.08Å; A172-I175 PolarHBondContact O-N 2.96Å; A172-L176 PolarHBondContact O-N 2.81Å
173	S	93.9	Very high	89.4	Confident	58 Å²	58	82.4 Å²	82.4	41%	0.406	40%	0.401	S	S	.	.	H	α-helix	trans	-66.6	-41.1	177.2	72	0	0	0	0	112.9	I169 Y170 I171 L176 V177	I169-S173 PolarHBondContact O-N 3.07Å; Y170-S173 PolarHBondContact O-N 3.38Å; Y170-S173 PolarHBondContact O-OG 3.06Å; I171-S173 VanDerWaalsContact C-N 3.25Å; I171-S173 PolarHBondContact O-N 2.96Å; S173-L176 WeakPolarHBondContact O-CB 3.46Å; S173-L176 PolarHBondContact O-N 2.89Å; S173-V177 WeakPolarHBondContact O-CG2 3.48Å; S173-V177 PolarHBondContact O-N 3.47Å; S173-V177 VanDerWaalsContact O-N 3.09Å
174	I	92.1	Very high	89.6	Confident	13 Å²	13	78.4 Å²	78.4	7%	0.067	39%	0.39	C	S	.	.	H	α-helix	trans	-67.8	-41.6	175.9	-64.3	-179.1	0	0	0	111	Y170 I171 L176 V177 I178 L199 A202 I203	Y170-I174 HydrophobicContact CD1-CD1 4.22Å; Y170-I174 HydrophobicContact CD2-CD1 4.45Å; Y170-I174 HydrophobicContact CE1-CD1 3.5Å; Y170-I174 VanDerWaalsContact CE1-CD1 3.5Å; Y170-I174 HydrophobicContact CE2-CD1 3.76Å; Y170-I174 HydrophobicContact CE2-CG1 4.37Å; Y170-I174 PolarHBondContact O-N 3.29Å; Y170-I174 VanDerWaalsContact OH-CD1 3.32Å; Y170-I174 WeakPolarHBondContact OH-CD1 3.24Å; I171-I174 PolarHBondContact O-N 2.92Å; I174-L176 PolarHBondContact O-N 3.37Å; I174-V177 WeakPolarHBondContact O-CB 3.29Å; I174-V177 PolarHBondContact O-N 3Å; I174-I178 HydrophobicContact CG2-CD1 3.91Å; I174-I178 HydrophobicContact CG2-CG1 4.22Å; I174-I178 WeakPolarHBondContact O-CG1 3.36Å; I174-I178 PolarHBondContact O-N 3.13Å; I174-L199 HydrophobicContact CG2-CB 4.07Å; I174-L199 HydrophobicContact CG2-CD2 4.17Å; I174-A202 HydrophobicContact CD1-CB 4.01Å; I174-I203 HydrophobicContact CB-CD1 4.01Å; I174-I203 HydrophobicContact CB-CG1 3.87Å; I174-I203 HydrophobicContact CD1-CG1 3.96Å; I174-I203 HydrophobicContact CG2-CD1 3.64Å; I174-I203 HydrophobicContact CG2-CG1 3.69Å
175	I	91.4	Very high	89.6	Confident	80 Å²	80	79.1 Å²	79.1	41%	0.41	39%	0.39	S	S	.	.	H	α-helix	trans	-58.3	-42.1	176.1	-69.3	172.1	0	0	0	110.2	I171 A172 V177 I178 L179 I203	I171-I175 HydrophobicContact CG2-CD1 3.64Å; I171-I175 HydrophobicContact CG2-CG1 4.21Å; I171-I175 WeakPolarHBondContact O-CG1 3.22Å; I171-I175 PolarHBondContact O-N 3.26Å; A172-I175 PolarHBondContact O-N 2.96Å; I175-V177 VanDerWaalsContact C-N 3.33Å; I175-V177 PolarHBondContact O-N 3.27Å; I175-I178 PolarHBondContact O-N 3.47Å; I175-L179 HydrophobicContact CG2-CD1 4.19Å; I175-L179 HydrophobicContact CG2-CG 4.42Å; I175-L179 WeakPolarHBondContact O-CG 3.26Å; I175-L179 PolarHBondContact O-N 2.82Å; I175-I203 HydrophobicContact CG1-CD1 4.11Å
176	L	93.3	Very high	89.5	Confident	104 Å²	104	74.6 Å²	74.6	55%	0.545	39%	0.387	S	S	.	.	H	α-helix	trans	-59.6	-43.4	174.9	-176.2	68.4	0	0	0	111.9	A172 S173 I174 L179 I180	A172-L176 PolarHBondContact O-N 2.81Å; S173-L176 WeakPolarHBondContact O-CB 3.46Å; S173-L176 PolarHBondContact O-N 2.89Å; I174-L176 PolarHBondContact O-N 3.37Å; L176-L179 PolarHBondContact O-N 3.22Å; L176-I180 HydrophobicContact CG-CD1 4.34Å; L176-I180 WeakPolarHBondContact O-CG1 3.33Å; L176-I180 PolarHBondContact O-N 3.47Å
177	V	93.1	Very high	89.4	Confident	69 Å²	69	72.8 Å²	72.8	42%	0.418	39%	0.389	S	S	.	.	H	α-helix	trans	-63.3	-43.8	176.1	174.7	0	0	0	0	111.2	S173 I174 I175 L179 I180 L181 L199	S173-V177 WeakPolarHBondContact O-CG2 3.48Å; S173-V177 PolarHBondContact O-N 3.47Å; S173-V177 VanDerWaalsContact O-N 3.09Å; I174-V177 WeakPolarHBondContact O-CB 3.29Å; I174-V177 PolarHBondContact O-N 3Å; I175-V177 VanDerWaalsContact C-N 3.33Å; I175-V177 PolarHBondContact O-N 3.27Å; V177-L179 VanDerWaalsContact C-N 3.33Å; V177-L179 PolarHBondContact O-N 3.14Å; V177-I180 PolarHBondContact O-N 3.42Å; V177-L181 HydrophobicContact CG1-CD1 4.11Å; V177-L181 HydrophobicContact CG1-CG 4.46Å; V177-L181 WeakPolarHBondContact O-CG 3.48Å; V177-L181 PolarHBondContact O-N 3.45Å; V177-L199 HydrophobicContact CG1-CD1 4.05Å
178	I	90.1	Very high	89	Confident	30 Å²	30	78.3 Å²	78.3	15%	0.154	42%	0.419	C	S	.	.	H	α-helix	trans	-59.6	-45.2	175.8	-67.6	170.8	0	0	0	110.1	I174 I175 I180 L181 L182 I196 L199 V200 I203	I174-I178 HydrophobicContact CG2-CD1 3.91Å; I174-I178 HydrophobicContact CG2-CG1 4.22Å; I174-I178 WeakPolarHBondContact O-CG1 3.36Å; I174-I178 PolarHBondContact O-N 3.13Å; I175-I178 PolarHBondContact O-N 3.47Å; I178-I180 VanDerWaalsContact C-N 3.32Å; I178-I180 PolarHBondContact O-N 3.3Å; I178-L181 CarbonylContact O-C 3.6Å; I178-L181 WeakPolarHBondContact O-CB 3.44Å; I178-L181 PolarHBondContact O-N 2.87Å; I178-L181 VanDerWaalsContact O-N 3.09Å; I178-L182 WeakPolarHBondContact O-CG 3.32Å; I178-L182 PolarHBondContact O-N 3.29Å; I178-I196 HydrophobicContact CG2-CG2 4.42Å; I178-L199 HydrophobicContact CD1-CB 4.11Å; I178-L199 HydrophobicContact CG1-CB 4.02Å; I178-L199 HydrophobicContact CG1-CD1 4.1Å; I178-V200 HydrophobicContact CD1-CG2 4.35Å; I178-I203 HydrophobicContact CD1-CD1 4.2Å
179	L	90.5	Very high	88.5	Confident	99 Å²	99	77 Å²	77	52%	0.518	42%	0.416	S	S	.	.	H	α-helix	trans	-59	-41.3	177.4	-73.1	171.6	0	0	0	112.3	I175 L176 V177 L181 L182	I175-L179 HydrophobicContact CG2-CD1 4.19Å; I175-L179 HydrophobicContact CG2-CG 4.42Å; I175-L179 WeakPolarHBondContact O-CG 3.26Å; I175-L179 PolarHBondContact O-N 2.82Å; L176-L179 PolarHBondContact O-N 3.22Å; V177-L179 VanDerWaalsContact C-N 3.33Å; V177-L179 PolarHBondContact O-N 3.14Å; L179-L181 VanDerWaalsContact C-N 3.35Å; L179-L182 HydrophobicContact CD2-CD1 4.04Å; L179-L182 WeakPolarHBondContact O-CB 3.24Å; L179-L182 PolarHBondContact O-N 2.9Å
180	I	90.9	Very high	87.8	Confident	101 Å²	101	77.1 Å²	77.1	52%	0.518	42%	0.421	S	S	.	.	H	α-helix	trans	-65	-41.1	175.4	-66.1	165.3	0	0	0	110.6	L176 V177 I178 L182 I183 P184	L176-I180 HydrophobicContact CG-CD1 4.34Å; L176-I180 WeakPolarHBondContact O-CG1 3.33Å; L176-I180 PolarHBondContact O-N 3.47Å; V177-I180 PolarHBondContact O-N 3.42Å; I178-I180 VanDerWaalsContact C-N 3.32Å; I178-I180 PolarHBondContact O-N 3.3Å; I180-L182 PolarHBondContact O-N 2.93Å; I180-I183 WeakPolarHBondContact O-CB 3.48Å; I180-I183 PolarHBondContact O-N 2.9Å; I180-P184 WeakPolarHBondContact O-CD 3.21Å
181	L	89.4	Confident	87.1	Confident	38 Å²	38	75.6 Å²	75.6	20%	0.199	43%	0.429	C	S	.	.	H	α-helix	trans	-66.8	-20.9	178	-72.3	174.6	0	0	0	113.6	V177 I178 L179 I183 P184 W185 V192 A195 I196 L199	V177-L181 HydrophobicContact CG1-CD1 4.11Å; V177-L181 HydrophobicContact CG1-CG 4.46Å; V177-L181 WeakPolarHBondContact O-CG 3.48Å; V177-L181 PolarHBondContact O-N 3.45Å; I178-L181 CarbonylContact O-C 3.6Å; I178-L181 WeakPolarHBondContact O-CB 3.44Å; I178-L181 PolarHBondContact O-N 2.87Å; I178-L181 VanDerWaalsContact O-N 3.09Å; L179-L181 VanDerWaalsContact C-N 3.35Å; L181-I183 PolarHBondContact O-N 3.25Å; L181-P184 HydrophobicContact CD2-CG 4.44Å; L181-P184 WeakPolarHBondContact O-CD 3.17Å; L181-P184 VanDerWaalsContact O-CG 3.29Å; L181-P184 WeakPolarHBondContact O-CG 3.38Å; L181-W185 WeakPolarHBondContact O-CB 3.44Å; L181-W185 PolarHBondContact O-N 3.05Å; L181-W185 VanDerWaalsContact O-N 3.12Å; L181-V192 HydrophobicContact CB-CG1 3.93Å; L181-V192 HydrophobicContact CD2-CG1 4.29Å; L181-V192 WeakPolarHBondContact O-CG1 3.35Å; L181-A195 HydrophobicContact CD1-CB 4.46Å; L181-I196 HydrophobicContact CB-CG1 4.45Å; L181-L199 HydrophobicContact CD1-CD1 3.41Å; L181-L199 VanDerWaalsContact CD1-CD1 3.41Å
182	L	85.5	Confident	86.6	Confident	70 Å²	70	74.8 Å²	74.8	37%	0.366	43%	0.426	S	S	.	.	H	α-helix	trans	-62	-27.6	172.7	-64.5	175.8	0	0	0	112.4	I178 L179 I180 W185 S186	I178-L182 WeakPolarHBondContact O-CG 3.32Å; I178-L182 PolarHBondContact O-N 3.29Å; L179-L182 HydrophobicContact CD2-CD1 4.04Å; L179-L182 WeakPolarHBondContact O-CB 3.24Å; L179-L182 PolarHBondContact O-N 2.9Å; I180-L182 PolarHBondContact O-N 2.93Å; L182-W185 HydrophobicContact CD2-CE3 3.53Å; L182-W185 HydrophobicContact CD2-CZ3 3.86Å; L182-W185 PolarHBondContact O-N 3.35Å; L182-S186 PolarHBondContact O-N 3.44Å
183	I	86.8	Confident	85.9	Confident	111 Å²	111	72.1 Å²	72.1	57%	0.569	40%	0.403	S	S	*	.	H	α-helix	trans	-63.6	-59.7	177.7	-58.8	168.2	0	0	0	111	I180 L181 W185 S186	I180-I183 WeakPolarHBondContact O-CB 3.48Å; I180-I183 PolarHBondContact O-N 2.9Å; L181-I183 PolarHBondContact O-N 3.25Å; I183-W185 PolarHBondContact O-N 2.87Å; I183-S186 WeakPolarHBondContact O-CB 3.31Å; I183-S186 PolarHBondContact O-N 3.47Å; I183-S186 VanDerWaalsContact O-N 3.1Å; I183-S186 PolarHBondContact O-OG 3.13Å
184	P	86.5	Confident	85.3	Confident	39 Å²	39	75 Å²	75	25%	0.253	41%	0.405	S	S	.	.	H	α-helix	trans	-65.4	-26.1	176.9	26.3	-34.8	0	0	0	112.6	I180 L181 S186 I187 V189 V192	I180-P184 WeakPolarHBondContact O-CD 3.21Å; L181-P184 HydrophobicContact CD2-CG 4.44Å; L181-P184 WeakPolarHBondContact O-CD 3.17Å; L181-P184 VanDerWaalsContact O-CG 3.29Å; L181-P184 WeakPolarHBondContact O-CG 3.38Å; P184-S186 VanDerWaalsContact C-N 3.33Å; P184-I187 PolarHBondContact O-N 2.94Å; P184-V189 HydrophobicContact CB-CG2 4.34Å; P184-V189 WeakPolarHBondContact O-CG2 3.4Å; P184-V189 PolarHBondContact O-N 3.07Å; P184-V192 HydrophobicContact CB-CG2 3.93Å; P184-V192 HydrophobicContact CG-CG2 3.93Å
185	W	81.2	Confident	85	Confident	104 Å²	104	76.3 Å²	76.3	39%	0.394	42%	0.418	S	S	.	.	H	α-helix	trans	-63.9	-38	171.9	-170.4	35.3	0	0	0	112.3	L181 L182 I183 I187 N188 V192 T193 I196	L181-W185 WeakPolarHBondContact O-CB 3.44Å; L181-W185 PolarHBondContact O-N 3.05Å; L181-W185 VanDerWaalsContact O-N 3.12Å; L182-W185 HydrophobicContact CD2-CE3 3.53Å; L182-W185 HydrophobicContact CD2-CZ3 3.86Å; L182-W185 PolarHBondContact O-N 3.35Å; I183-W185 PolarHBondContact O-N 2.87Å; W185-I187 PolarHBondContact O-N 3.41Å; W185-I187 VanDerWaalsContact O-N 3.15Å; W185-N188 PolarHBondContact O-N 3.13Å; W185-V192 HydrophobicContact CB-CB 4.38Å; W185-V192 HydrophobicContact CB-CG1 3.91Å; W185-T193 HydrophobicContact CZ2-CG2 4.42Å; W185-I196 HydrophobicContact CD2-CD1 4.44Å; W185-I196 HydrophobicContact CE3-CD1 4.48Å
186	S	81.5	Confident	84.8	Confident	92 Å²	92	73 Å²	73	64%	0.643	40%	0.402	S	S	*	.	H	α-helix	trans	-63.2	-19	175.9	77	0	0	0	0	114.1	L182 I183 P184 N188	L182-S186 PolarHBondContact O-N 3.44Å; I183-S186 WeakPolarHBondContact O-CB 3.31Å; I183-S186 PolarHBondContact O-N 3.47Å; I183-S186 VanDerWaalsContact O-N 3.1Å; I183-S186 PolarHBondContact O-OG 3.13Å; P184-S186 VanDerWaalsContact C-N 3.33Å; S186-N188 VanDerWaalsContact C-N 3.33Å
187	I	85.7	Confident	84.6	Confident	127 Å²	127	68.1 Å²	68.1	65%	0.651	38%	0.376	S	S	*	.	T	Hydrogen-bonded Turn	trans	-98.9	17.6	176.6	-38.1	173.5	0	0	0	110.5	P184 W185 V189	P184-I187 PolarHBondContact O-N 2.94Å; W185-I187 PolarHBondContact O-N 3.41Å; W185-I187 VanDerWaalsContact O-N 3.15Å; I187-V189 VanDerWaalsContact C-N 3.33Å; I187-V189 PolarHBondContact O-N 2.88Å
188	N	79.2	Confident	84.5	Confident	137 Å²	137	67.5 Å²	67.5	73%	0.733	37%	0.373	S	S	*	.	T	Hydrogen-bonded Turn	trans	58.5	33.3	177.4	-67.1	-30.8	0	0	0	115.3	W185 S186 T190	W185-N188 PolarHBondContact O-N 3.13Å; S186-N188 VanDerWaalsContact C-N 3.33Å; N188-T190 PolarHBondContact O-N 3.09Å
189	V	79.5	Confident	84.6	Confident	68 Å²	68	68 Å²	68	41%	0.412	38%	0.376	S	S	.	.			trans	-73.6	100.6	170	-176.6	0	0	0	0	109.2	P184 I187 A191 V192	P184-V189 HydrophobicContact CB-CG2 4.34Å; P184-V189 WeakPolarHBondContact O-CG2 3.4Å; P184-V189 PolarHBondContact O-N 3.07Å; I187-V189 VanDerWaalsContact C-N 3.33Å; I187-V189 PolarHBondContact O-N 2.88Å; V189-A191 HydrophobicContact CG1-CB 4.31Å; V189-A191 PolarHBondContact O-N 3.35Å; V189-V192 HydrophobicContact CB-CG2 3.85Å; V189-V192 HydrophobicContact CG1-CG2 3.88Å; V189-V192 WeakPolarHBondContact O-CB 3.37Å; V189-V192 WeakPolarHBondContact O-CG2 3.09Å; V189-V192 PolarHBondContact O-N 3.05Å
190	T	75.7	Confident	84.6	Confident	94 Å²	94	64 Å²	64	58%	0.577	36%	0.356	S	S	*	.	H	α-helix	trans	-60.3	-26.5	-175.6	50.2	0	0	0	0	114.1	N188 V192 T193	N188-T190 PolarHBondContact O-N 3.09Å; T190-V192 PolarHBondContact O-N 2.91Å; T190-T193 PolarHBondContact O-N 3.04Å; T190-T193 PolarHBondContact O-OG1 3.3Å
191	A	78.9	Confident	84.7	Confident	67 Å²	67	60.1 Å²	60.1	55%	0.554	34%	0.336	S	S	*	.	H	α-helix	trans	-63.2	-22.8	175.5	0	0	0	0	0	113	V189 W194 A195	V189-A191 HydrophobicContact CG1-CB 4.31Å; V189-A191 PolarHBondContact O-N 3.35Å; A191-W194 PolarHBondContact O-N 2.95Å; A191-A195 PolarHBondContact O-N 3.5Å
192	V	80.9	Confident	84.9	Confident	11 Å²	11	59.6 Å²	59.6	7%	0.067	34%	0.337	C	S	.	.	H	α-helix	trans	-73.3	-36.6	-176	-179.7	0	0	0	0	112	L181 P184 W185 V189 T190 W194 A195 I196	L181-V192 HydrophobicContact CB-CG1 3.93Å; L181-V192 HydrophobicContact CD2-CG1 4.29Å; L181-V192 WeakPolarHBondContact O-CG1 3.35Å; P184-V192 HydrophobicContact CB-CG2 3.93Å; P184-V192 HydrophobicContact CG-CG2 3.93Å; W185-V192 HydrophobicContact CB-CB 4.38Å; W185-V192 HydrophobicContact CB-CG1 3.91Å; V189-V192 HydrophobicContact CB-CG2 3.85Å; V189-V192 HydrophobicContact CG1-CG2 3.88Å; V189-V192 WeakPolarHBondContact O-CB 3.37Å; V189-V192 WeakPolarHBondContact O-CG2 3.09Å; V189-V192 PolarHBondContact O-N 3.05Å; T190-V192 PolarHBondContact O-N 2.91Å; V192-W194 PolarHBondContact O-N 3Å; V192-A195 PolarHBondContact O-N 3.24Å; V192-I196 HydrophobicContact CG1-CD1 3.82Å; V192-I196 HydrophobicContact CG1-CG1 4.17Å; V192-I196 WeakPolarHBondContact O-CG1 3.48Å; V192-I196 PolarHBondContact O-N 2.98Å
193	T	77.2	Confident	85.2	Confident	3 Å²	3	57.8 Å²	57.8	2%	0.018	33%	0.327	C	S	.	.	H	α-helix	trans	-61.2	-37.8	176.5	49.4	0	0	0	0	111.4	W185 T190 A195 I196 G197 N252	W185-T193 HydrophobicContact CZ2-CG2 4.42Å; T190-T193 PolarHBondContact O-N 3.04Å; T190-T193 PolarHBondContact O-OG1 3.3Å; T193-A195 VanDerWaalsContact C-N 3.26Å; T193-A195 PolarHBondContact O-N 2.89Å; T193-I196 PolarHBondContact O-N 3.01Å; T193-G197 PolarHBondContact O-N 2.86Å; T193-N252 PolarHBondContact OG1-ND2 2.85Å
194	W	80.8	Confident	85.5	Confident	118 Å²	118	52.7 Å²	52.7	45%	0.447	30%	0.301	S	S	.	.	H	α-helix	trans	-66.1	-25.4	174.9	-74.4	91.3	0	0	0	113.5	A191 V192 P198 I253	A191-W194 PolarHBondContact O-N 2.95Å; V192-W194 PolarHBondContact O-N 3Å; W194-P198 WeakPolarHBondContact O-CD 3.34Å; W194-P198 VanDerWaalsContact O-CG 3.26Å; W194-P198 WeakPolarHBondContact O-CG 3.37Å; W194-I253 HydrophobicContact CH2-CD1 3.65Å; W194-I253 HydrophobicContact CH2-CG1 3.85Å; W194-I253 HydrophobicContact CZ2-CD1 4.07Å; W194-I253 HydrophobicContact CZ2-CG1 3.71Å
195	A	86.5	Confident	85.8	Confident	41 Å²	41	54.1 Å²	54.1	34%	0.339	31%	0.306	S	S	.	.	H	α-helix	trans	-85.3	-34.7	176.4	0	0	0	0	0	112.6	L181 A191 V192 T193 P198 L199	L181-A195 HydrophobicContact CD1-CB 4.46Å; A191-A195 PolarHBondContact O-N 3.5Å; V192-A195 PolarHBondContact O-N 3.24Å; T193-A195 VanDerWaalsContact C-N 3.26Å; T193-A195 PolarHBondContact O-N 2.89Å; A195-P198 WeakPolarHBondContact O-CD 3.4Å; A195-L199 VanDerWaalsContact O-CG 3.28Å; A195-L199 WeakPolarHBondContact O-CG 3.11Å; A195-L199 PolarHBondContact O-N 2.83Å
196	I	88	Confident	86.3	Confident	11 Å²	11	50.6 Å²	50.6	6%	0.056	30%	0.297	C	S	.	.	H	α-helix	trans	-66.4	-43.1	-178	-64.7	163.9	0	0	0	111.1	I178 L181 W185 V192 T193 L199 V200 L248	I178-I196 HydrophobicContact CG2-CG2 4.42Å; L181-I196 HydrophobicContact CB-CG1 4.45Å; W185-I196 HydrophobicContact CD2-CD1 4.44Å; W185-I196 HydrophobicContact CE3-CD1 4.48Å; V192-I196 HydrophobicContact CG1-CD1 3.82Å; V192-I196 HydrophobicContact CG1-CG1 4.17Å; V192-I196 WeakPolarHBondContact O-CG1 3.48Å; V192-I196 PolarHBondContact O-N 2.98Å; T193-I196 PolarHBondContact O-N 3.01Å; I196-L199 WeakPolarHBondContact O-CB 3.5Å; I196-L199 PolarHBondContact O-N 3.24Å; I196-L199 VanDerWaalsContact O-N 3.13Å; I196-V200 HydrophobicContact CG2-CG2 4.26Å; I196-V200 WeakPolarHBondContact O-CG2 3.43Å; I196-V200 PolarHBondContact O-N 3.16Å; I196-L248 HydrophobicContact CG2-CD1 4.1Å
197	G	88	Confident	86.8	Confident	0 Å²	0	47 Å²	47	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-55.1	-53.4	-179.8	0	0	0	0	0	113.9	T193 L199 V200 L201 G245	T193-G197 PolarHBondContact O-N 2.86Å; G197-L199 VanDerWaalsContact C-N 3.3Å; G197-L199 PolarHBondContact O-N 3.42Å; G197-V200 WeakPolarHBondContact O-CB 3.46Å; G197-V200 PolarHBondContact O-N 3.41Å; G197-L201 PolarHBondContact O-N 3.11Å; G197-G245 WeakPolarHBondContact CA-O 3.46Å
198	P	91.4	Very high	87.1	Confident	56 Å²	56	41.5 Å²	41.5	36%	0.364	25%	0.245	S	C	.	.	H	α-helix	trans	-59.9	-34.8	173.7	-26.7	35.7	0	0	0	114	W194 A195 L201 A202 M249	W194-P198 WeakPolarHBondContact O-CD 3.34Å; W194-P198 VanDerWaalsContact O-CG 3.26Å; W194-P198 WeakPolarHBondContact O-CG 3.37Å; A195-P198 WeakPolarHBondContact O-CD 3.4Å; P198-L201 PolarHBondContact O-N 3.46Å; P198-A202 WeakPolarHBondContact O-CB 3.05Å; P198-A202 PolarHBondContact O-N 3.45Å; P198-M249 HydrophobicContact CG-CE 3.86Å; P198-M249 HydrophobicContact CG-CG 4.42Å; P198-M249 HydrophobicContact CG-SD 4Å
199	L	92.7	Very high	87.7	Confident	40 Å²	40	36.2 Å²	36.2	21%	0.209	22%	0.217	C	C	.	.	H	α-helix	trans	-66.4	-38.5	175.6	-72	170.6	0	0	0	111.9	I174 V177 I178 L181 A195 I196 G197 A202 I203	I174-L199 HydrophobicContact CG2-CB 4.07Å; I174-L199 HydrophobicContact CG2-CD2 4.17Å; V177-L199 HydrophobicContact CG1-CD1 4.05Å; I178-L199 HydrophobicContact CD1-CB 4.11Å; I178-L199 HydrophobicContact CG1-CB 4.02Å; I178-L199 HydrophobicContact CG1-CD1 4.1Å; L181-L199 HydrophobicContact CD1-CD1 3.41Å; L181-L199 VanDerWaalsContact CD1-CD1 3.41Å; A195-L199 VanDerWaalsContact O-CG 3.28Å; A195-L199 WeakPolarHBondContact O-CG 3.11Å; A195-L199 PolarHBondContact O-N 2.83Å; I196-L199 WeakPolarHBondContact O-CB 3.5Å; I196-L199 PolarHBondContact O-N 3.24Å; I196-L199 VanDerWaalsContact O-N 3.13Å; G197-L199 VanDerWaalsContact C-N 3.3Å; G197-L199 PolarHBondContact O-N 3.42Å; L199-A202 WeakPolarHBondContact O-CB 3.24Å; L199-A202 PolarHBondContact O-N 3.19Å; L199-I203 PolarHBondContact O-N 3.08Å
200	V	90.9	Very high	88.2	Confident	16 Å²	16	33.6 Å²	33.6	10%	0.097	20%	0.2	C	C	.	.	H	α-helix	trans	-61.5	-46.5	172	173.8	0	0	0	0	110	I178 I196 G197 A202 I203 I204 F241 L248	I178-V200 HydrophobicContact CD1-CG2 4.35Å; I196-V200 HydrophobicContact CG2-CG2 4.26Å; I196-V200 WeakPolarHBondContact O-CG2 3.43Å; I196-V200 PolarHBondContact O-N 3.16Å; G197-V200 WeakPolarHBondContact O-CB 3.46Å; G197-V200 PolarHBondContact O-N 3.41Å; V200-A202 VanDerWaalsContact C-N 3.3Å; V200-A202 PolarHBondContact O-N 2.9Å; V200-I203 WeakPolarHBondContact O-CB 3.37Å; V200-I203 PolarHBondContact O-N 3.1Å; V200-I204 HydrophobicContact CG1-CD1 3.99Å; V200-I204 WeakPolarHBondContact O-CG1 3.29Å; V200-I204 PolarHBondContact O-N 3.33Å; V200-F241 HydrophobicContact CG1-CD1 4.29Å; V200-F241 WeakPolarHBondContact CG1-O 3.06Å; V200-L248 HydrophobicContact CG2-CD1 4.32Å
201	L	92.9	Very high	88.9	Confident	20 Å²	20	29.4 Å²	29.4	11%	0.105	17%	0.174	C	C	.	.	H	α-helix	trans	-62.9	-35	176.3	-65.6	177.1	0	0	0	112.7	L145 G197 P198 I203 I204 I205 F246 M249	L145-L201 HydrophobicContact CD2-CD2 4.13Å; G197-L201 PolarHBondContact O-N 3.11Å; P198-L201 PolarHBondContact O-N 3.46Å; L201-I203 VanDerWaalsContact C-N 3.26Å; L201-I203 PolarHBondContact O-N 2.72Å; L201-I204 PolarHBondContact O-N 3.19Å; L201-I205 WeakPolarHBondContact O-CG1 3.36Å; L201-I205 PolarHBondContact O-N 3.42Å; L201-F246 HydrophobicContact CD1-CD1 4.28Å; L201-F246 HydrophobicContact CD1-CE1 3.88Å; L201-F246 HydrophobicContact CD1-CZ 4.03Å; L201-F246 HydrophobicContact CD2-CD2 4.43Å; L201-F246 HydrophobicContact CD2-CE2 4.12Å; L201-F246 HydrophobicContact CD2-CZ 4.33Å; L201-M249 HydrophobicContact CD1-SD 4.21Å
202	A	93	Very high	89.4	Confident	27 Å²	27	26.2 Å²	26.2	22%	0.223	15%	0.148	C	C	.	.	H	α-helix	trans	-63.9	-29.6	176.8	0	0	0	0	0	113	Y170 I174 P198 L199 V200 P206	Y170-A202 PolarHBondContact OH-O 3.35Å; I174-A202 HydrophobicContact CD1-CB 4.01Å; P198-A202 WeakPolarHBondContact O-CB 3.05Å; P198-A202 PolarHBondContact O-N 3.45Å; L199-A202 WeakPolarHBondContact O-CB 3.24Å; L199-A202 PolarHBondContact O-N 3.19Å; V200-A202 VanDerWaalsContact C-N 3.3Å; V200-A202 PolarHBondContact O-N 2.9Å; A202-P206 WeakPolarHBondContact O-CD 3.31Å; A202-P206 WeakPolarHBondContact O-CG 3.28Å
203	I	92.5	Very high	89.7	Confident	31 Å²	31	26.5 Å²	26.5	16%	0.159	15%	0.148	C	C	.	.	H	α-helix	trans	-71	-40.6	170.6	-68.1	172.5	0	0	0	110.8	I171 I174 I175 I178 L199 V200 L201 P206	I171-I203 HydrophobicContact CG1-CG2 4.23Å; I171-I203 HydrophobicContact CG2-CG2 4.18Å; I174-I203 HydrophobicContact CB-CD1 4.01Å; I174-I203 HydrophobicContact CB-CG1 3.87Å; I174-I203 HydrophobicContact CD1-CG1 3.96Å; I174-I203 HydrophobicContact CG2-CD1 3.64Å; I174-I203 HydrophobicContact CG2-CG1 3.69Å; I175-I203 HydrophobicContact CG1-CD1 4.11Å; I178-I203 HydrophobicContact CD1-CD1 4.2Å; L199-I203 PolarHBondContact O-N 3.08Å; V200-I203 WeakPolarHBondContact O-CB 3.37Å; V200-I203 PolarHBondContact O-N 3.1Å; L201-I203 VanDerWaalsContact C-N 3.26Å; L201-I203 PolarHBondContact O-N 2.72Å; I203-P206 WeakPolarHBondContact O-CG 3.36Å
204	I	92.9	Very high	90.1	Very high	4 Å²	4	26.8 Å²	26.8	2%	0.021	15%	0.15	C	C	.	.	H	α-helix	trans	-77.3	-41.5	-169.5	-63.4	170.5	0	0	0	112.4	V200 L201 A207 S208 F241	V200-I204 HydrophobicContact CG1-CD1 3.99Å; V200-I204 WeakPolarHBondContact O-CG1 3.29Å; V200-I204 PolarHBondContact O-N 3.33Å; L201-I204 PolarHBondContact O-N 3.19Å; I204-A207 CarbonylContact O-C 3.6Å; I204-A207 WeakPolarHBondContact O-CA 3.33Å; I204-A207 WeakPolarHBondContact O-CB 3.4Å; I204-A207 PolarHBondContact O-N 3.01Å; I204-S208 WeakPolarHBondContact CG2-OG 3.38Å; I204-S208 PolarHBondContact O-N 3.42Å; I204-S208 PolarHBondContact O-OG 2.88Å; I204-F241 HydrophobicContact CD1-CB 3.49Å; I204-F241 VanDerWaalsContact CD1-CB 3.49Å; I204-F241 WeakPolarHBondContact CD1-O 3.43Å; I204-F241 HydrophobicContact CG1-CB 4.07Å
205	I	92.7	Very high	90.4	Very high	69 Å²	69	21.2 Å²	21.2	35%	0.354	13%	0.129	S	C	.	.	H	α-helix	trans	-47.8	-58.3	-179.3	-71.8	164	0	0	0	111.5	L149 L201 A207 S208 L209	L149-I205 HydrophobicContact CD1-CG1 4.23Å; L149-I205 HydrophobicContact CD2-CB 4.43Å; L149-I205 HydrophobicContact CD2-CG1 4.39Å; L149-I205 HydrophobicContact CD2-CG2 3.91Å; L201-I205 WeakPolarHBondContact O-CG1 3.36Å; L201-I205 PolarHBondContact O-N 3.42Å; I205-A207 PolarHBondContact O-N 3.12Å; I205-S208 PolarHBondContact O-N 3.25Å; I205-L209 HydrophobicContact CG2-CD1 4.26Å; I205-L209 VanDerWaalsContact O-CG 3.28Å; I205-L209 WeakPolarHBondContact O-CG 3.32Å; I205-L209 PolarHBondContact O-N 3.29Å; I205-L209 VanDerWaalsContact O-N 3.13Å
206	P	91.3	Very high	90.1	Very high	31 Å²	31	23.1 Å²	23.1	20%	0.201	13%	0.128	C	C	.	.	H	α-helix	trans	-65.4	-34.9	176.6	24.6	-34.8	0	0	0	113.7	F167 Y170 A202 I203 L209 I210	F167-P206 HydrophobicContact CD2-CB 3.87Å; F167-P206 HydrophobicContact CD2-CG 4.13Å; F167-P206 HydrophobicContact CE2-CB 3.44Å; F167-P206 VanDerWaalsContact CE2-CB 3.44Å; F167-P206 HydrophobicContact CE2-CG 3.32Å; F167-P206 HydrophobicContact CZ-CB 4.1Å; F167-P206 HydrophobicContact CZ-CG 4Å; Y170-P206 HydrophobicContact CD1-CG 4.46Å; Y170-P206 HydrophobicContact CE1-CG 3.91Å; A202-P206 WeakPolarHBondContact O-CD 3.31Å; A202-P206 WeakPolarHBondContact O-CG 3.28Å; I203-P206 WeakPolarHBondContact O-CG 3.36Å; P206-L209 PolarHBondContact O-N 3.42Å; P206-I210 WeakPolarHBondContact O-CG1 3.34Å; P206-I210 PolarHBondContact O-N 3.38Å; P206-I210 VanDerWaalsContact O-N 3.07Å
207	A	91.8	Very high	89.3	Confident	17 Å²	17	23.3 Å²	23.3	14%	0.14	13%	0.132	C	C	.	.	H	α-helix	trans	-61.8	-45.8	177.1	0	0	0	0	0	112.1	F167 I204 I205 I210 E211 L238	F167-A207 HydrophobicContact CE1-CB 4.03Å; F167-A207 HydrophobicContact CZ-CB 3.73Å; I204-A207 CarbonylContact O-C 3.6Å; I204-A207 WeakPolarHBondContact O-CA 3.33Å; I204-A207 WeakPolarHBondContact O-CB 3.4Å; I204-A207 PolarHBondContact O-N 3.01Å; I205-A207 PolarHBondContact O-N 3.12Å; A207-I210 PolarHBondContact O-N 3.19Å; A207-E211 WeakPolarHBondContact O-CB 3.2Å; A207-E211 PolarHBondContact O-N 3.39Å; A207-L238 HydrophobicContact CB-CD2 3.59Å
208	S	92.8	Very high	88.1	Confident	10 Å²	10	23.6 Å²	23.6	7%	0.07	14%	0.136	C	C	.	.	H	α-helix	trans	-67.7	-34.8	178.3	-64.1	0	0	0	0	112.5	I204 I205 E211 A212	I204-S208 WeakPolarHBondContact CG2-OG 3.38Å; I204-S208 PolarHBondContact O-N 3.42Å; I204-S208 PolarHBondContact O-OG 2.88Å; I205-S208 PolarHBondContact O-N 3.25Å; S208-E211 PolarHBondContact O-N 2.81Å; S208-A212 WeakPolarHBondContact O-CB 3.32Å; S208-A212 PolarHBondContact O-N 3.44Å
209	L	92.1	Very high	86.9	Confident	26 Å²	26	27.7 Å²	27.7	14%	0.136	14%	0.144	C	C	.	.	H	α-helix	trans	-64.7	-43.7	174.1	-69.3	170.9	0	0	0	111.7	L149 V152 I156 L160 I205 P206 A212 Q213	L149-L209 HydrophobicContact CD2-CD2 4.23Å; L149-L209 HydrophobicContact CD2-CG 4.29Å; L149-L209 WeakPolarHBondContact O-CD2 3.43Å; V152-L209 HydrophobicContact CB-CD2 4.11Å; V152-L209 HydrophobicContact CG1-CD2 3.85Å; I156-L209 HydrophobicContact CD1-CD2 4.15Å; L160-L209 HydrophobicContact CD1-CB 3.78Å; I205-L209 HydrophobicContact CG2-CD1 4.26Å; I205-L209 VanDerWaalsContact O-CG 3.28Å; I205-L209 WeakPolarHBondContact O-CG 3.32Å; I205-L209 PolarHBondContact O-N 3.29Å; I205-L209 VanDerWaalsContact O-N 3.13Å; P206-L209 PolarHBondContact O-N 3.42Å; L209-A212 PolarHBondContact O-N 2.87Å; L209-Q213 PolarHBondContact O-N 3.44Å
210	I	89.5	Confident	85.7	Confident	13 Å²	13	28.2 Å²	28.2	7%	0.067	15%	0.145	C	C	.	.	H	α-helix	trans	-63.9	-45.8	175.1	-68.4	166.5	0	0	0	110	L160 V161 F167 P206 A207 A212 Q213 I214	L160-I210 HydrophobicContact CB-CG1 3.88Å; V161-I210 HydrophobicContact CG2-CG2 4.46Å; F167-I210 HydrophobicContact CB-CD1 4.12Å; F167-I210 HydrophobicContact CD1-CD1 3.46Å; F167-I210 VanDerWaalsContact CD1-CD1 3.46Å; F167-I210 HydrophobicContact CD2-CD1 4.38Å; F167-I210 HydrophobicContact CE1-CD1 3.94Å; F167-I210 HydrophobicContact CG-CD1 3.7Å; P206-I210 WeakPolarHBondContact O-CG1 3.34Å; P206-I210 PolarHBondContact O-N 3.38Å; P206-I210 VanDerWaalsContact O-N 3.07Å; A207-I210 PolarHBondContact O-N 3.19Å; I210-A212 VanDerWaalsContact C-N 3.32Å; I210-A212 PolarHBondContact O-N 2.78Å; I210-Q213 PolarHBondContact O-N 3.39Å; I210-I214 HydrophobicContact CG2-CD1 3.78Å; I210-I214 HydrophobicContact CG2-CG1 4.37Å; I210-I214 WeakPolarHBondContact O-CG1 3.24Å; I210-I214 PolarHBondContact O-N 3.02Å
211	E	90.1	Very high	84.7	Confident	7 Å²	7	28.5 Å²	28.5	3%	0.033	15%	0.146	C	C	.	.	H	α-helix	trans	-58.1	-44	177.7	-168.9	-147.9	-169.3	0	0	111.9	A207 S208 Q213 I214 L215 I234 H235 L238	A207-E211 WeakPolarHBondContact O-CB 3.2Å; A207-E211 PolarHBondContact O-N 3.39Å; S208-E211 PolarHBondContact O-N 2.81Å; E211-Q213 VanDerWaalsContact C-N 3.29Å; E211-Q213 PolarHBondContact O-N 2.9Å; E211-I214 PolarHBondContact O-N 3.33Å; E211-I214 VanDerWaalsContact O-N 3.12Å; E211-L215 HydrophobicContact CG-CD1 4.06Å; E211-L215 HydrophobicContact CG-CG 4.39Å; E211-L215 WeakPolarHBondContact O-CB 3.38Å; E211-L215 WeakPolarHBondContact O-CG 3.28Å; E211-L215 PolarHBondContact O-N 2.97Å; E211-I234 HydrophobicContact CG-CG2 4.05Å; E211-H235 WeakPolarHBondContact OE1-CA 3.43Å; E211-H235 WeakPolarHBondContact OE1-CB 3.37Å; E211-H235 IonicContact OE1-CG 2.72Å; E211-H235 PolarHBondContact OE1-N 3.45Å; E211-H235 VanDerWaalsContact OE1-N 3.14Å; E211-H235 IonicContact OE1-ND1 3.63Å; E211-H235 PolarHBondContact OE1-ND1 3.41Å; E211-H235 IonicContact OE2-CE1 3.54Å; E211-H235 IonicContact OE2-CG 3.22Å; E211-H235 IonicContact OE2-ND1 3.68Å; E211-H235 PolarHBondContact OE2-ND1 2.88Å; E211-L238 HydrophobicContact CB-CD1 3.92Å; E211-L238 HydrophobicContact CG-CD1 4.15Å; E211-L238 WeakPolarHBondContact OE2-CD1 3.45Å
212	A	89.1	Confident	84	Confident	0 Å²	0	29 Å²	29	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-57.9	-42.2	177.6	0	0	0	0	0	111.9	F150 S208 L209 I210 L215 Y216	F150-A212 HydrophobicContact CD2-CB 3.61Å; F150-A212 HydrophobicContact CE2-CB 4.03Å; F150-A212 HydrophobicContact CG-CB 4.23Å; S208-A212 WeakPolarHBondContact O-CB 3.32Å; S208-A212 PolarHBondContact O-N 3.44Å; L209-A212 PolarHBondContact O-N 2.87Å; I210-A212 VanDerWaalsContact C-N 3.32Å; I210-A212 PolarHBondContact O-N 2.78Å; A212-L215 PolarHBondContact O-N 3.09Å; A212-Y216 WeakPolarHBondContact O-CB 3.4Å; A212-Y216 PolarHBondContact O-N 2.93Å
213	Q	87.3	Confident	83.2	Confident	16 Å²	16	28 Å²	28	8%	0.075	14%	0.137	C	C	.	.	H	α-helix	trans	-65.2	-43.5	174.7	-69.8	-167.8	-20.3	0	0	111.9	G153 I156 R158 L160 L209 I210 E211 L215 Y216 G217 G218	G153-Q213 VanDerWaalsContact O-CG 3.26Å; G153-Q213 WeakPolarHBondContact O-CG 3.07Å; G153-Q213 PolarHBondContact O-NE2 3.48Å; I156-Q213 PolarHBondContact O-NE2 3.43Å; R158-Q213 PolarHBondContact O-NE2 3.4Å; L160-Q213 VanDerWaalsContact CB-OE1 3.24Å; L209-Q213 PolarHBondContact O-N 3.44Å; I210-Q213 PolarHBondContact O-N 3.39Å; E211-Q213 VanDerWaalsContact C-N 3.29Å; E211-Q213 PolarHBondContact O-N 2.9Å; Q213-L215 VanDerWaalsContact C-N 3.34Å; Q213-L215 PolarHBondContact O-N 3.33Å; Q213-Y216 PolarHBondContact O-N 3.24Å; Q213-G217 CarbonylContact O-C 3.52Å; Q213-G217 PolarHBondContact O-N 3.36Å; Q213-G218 WeakPolarHBondContact O-CA 3.39Å; Q213-G218 PolarHBondContact O-N 3.45Å
214	I	85.8	Confident	82.3	Confident	10 Å²	10	31.4 Å²	31.4	5%	0.051	15%	0.148	C	C	.	.	H	α-helix	trans	-63.6	-40.1	177.9	-61.6	169.7	0	0	0	111.2	L2 R39 V161 I210 E211 G217 I221 Y223	L2-I214 HydrophobicContact CD2-CG2 4.32Å; R39-I214 PolarHBondContact NH2-O 3.36Å; V161-I214 HydrophobicContact CG2-CG1 3.96Å; I210-I214 HydrophobicContact CG2-CD1 3.78Å; I210-I214 HydrophobicContact CG2-CG1 4.37Å; I210-I214 WeakPolarHBondContact O-CG1 3.24Å; I210-I214 PolarHBondContact O-N 3.02Å; E211-I214 PolarHBondContact O-N 3.33Å; E211-I214 VanDerWaalsContact O-N 3.12Å; I214-G217 PolarHBondContact O-N 3.46Å; I214-I221 HydrophobicContact CD1-CG2 4.1Å; I214-I221 HydrophobicContact CG1-CG2 4.03Å; I214-I221 HydrophobicContact CG2-CG2 4.03Å; I214-Y223 HydrophobicContact CB-CD2 4.47Å; I214-Y223 HydrophobicContact CB-CE2 4.15Å; I214-Y223 HydrophobicContact CG2-CD2 3.53Å; I214-Y223 HydrophobicContact CG2-CE1 4.43Å; I214-Y223 HydrophobicContact CG2-CE2 3.44Å; I214-Y223 VanDerWaalsContact CG2-CE2 3.44Å; I214-Y223 HydrophobicContact CG2-CG 4.1Å
215	L	86.4	Confident	81.2	Confident	0 Å²	0	37.2 Å²	37.2	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-65.7	-42.8	175.7	-80.2	171.5	0	0	0	111.8	R39 F42 V46 F150 E211 A212 Q213 G217 Y223 A231	R39-L215 VanDerWaalsContact CZ-O 3.23Å; R39-L215 PolarHBondContact NE-O 3.23Å; R39-L215 PolarHBondContact NH2-O 3.12Å; F42-L215 HydrophobicContact CE1-CD2 3.87Å; V46-L215 HydrophobicContact CG1-CD2 4.38Å; V46-L215 HydrophobicContact CG2-CD2 4.29Å; F150-L215 HydrophobicContact CD2-CD1 4.35Å; F150-L215 HydrophobicContact CE2-CB 3.92Å; F150-L215 HydrophobicContact CE2-CD1 3.69Å; F150-L215 HydrophobicContact CE2-CG 4.46Å; F150-L215 HydrophobicContact CZ-CB 4.4Å; E211-L215 HydrophobicContact CG-CD1 4.06Å; E211-L215 HydrophobicContact CG-CG 4.39Å; E211-L215 WeakPolarHBondContact O-CB 3.38Å; E211-L215 WeakPolarHBondContact O-CG 3.28Å; E211-L215 PolarHBondContact O-N 2.97Å; A212-L215 PolarHBondContact O-N 3.09Å; Q213-L215 VanDerWaalsContact C-N 3.34Å; Q213-L215 PolarHBondContact O-N 3.33Å; L215-G217 VanDerWaalsContact C-N 3.25Å; L215-G217 PolarHBondContact O-N 2.85Å; L215-Y223 HydrophobicContact CD2-CD2 3.81Å; L215-Y223 HydrophobicContact CD2-CE2 3.88Å; L215-Y223 HydrophobicContact CG-CD2 4.24Å; L215-Y223 HydrophobicContact CG-CE2 4.03Å; L215-A231 HydrophobicContact CD2-CB 3.92Å
216	Y	81.7	Confident	80.2	Confident	81 Å²	81	40.3 Å²	40.3	32%	0.318	18%	0.183	S	C	.	.	H	α-helix	trans	-66	-29	177.4	-171.3	-102.2	0	0	0	112.8	I35 R39 I43 I154 A212 Q213	I35-Y216 HydrophobicContact CD1-CE2 3.74Å; I35-Y216 HydrophobicContact CG1-CE2 3.79Å; I35-Y216 WeakPolarHBondContact CG1-OH 3.32Å; I35-Y216 HydrophobicContact CG2-CE2 4.23Å; R39-Y216 WeakPolarHBondContact CG-O 3.41Å; R39-Y216 PolarHBondContact NE-O 3.44Å; I43-Y216 HydrophobicContact CD1-CD2 4.46Å; I154-Y216 HydrophobicContact CB-CD2 4.16Å; I154-Y216 HydrophobicContact CB-CG 4.34Å; I154-Y216 HydrophobicContact CG2-CD2 3.86Å; I154-Y216 HydrophobicContact CG2-CG 4Å; A212-Y216 WeakPolarHBondContact O-CB 3.4Å; A212-Y216 PolarHBondContact O-N 2.93Å; Q213-Y216 PolarHBondContact O-N 3.24Å
217	G	70.1	Confident	79.6	Confident	15 Å²	15	40.7 Å²	40.7	16%	0.155	18%	0.183	C	C	.	.			trans	116.1	68.2	-177.1	0	0	0	0	0	109	I25 Q213 I214 L215	I25-G217 WeakPolarHBondContact CD1-O 3.35Å; Q213-G217 CarbonylContact O-C 3.52Å; Q213-G217 PolarHBondContact O-N 3.36Å; I214-G217 PolarHBondContact O-N 3.46Å; L215-G217 VanDerWaalsContact C-N 3.25Å; L215-G217 PolarHBondContact O-N 2.85Å
218	G	63.4	Low	79.2	Confident	7 Å²	7	41.2 Å²	41.2	7%	0.072	18%	0.182	C	C	.	.			trans	-60.4	158.4	-176.4	0	0	0	0	0	112.4	I25 Q213 I221	I25-G218 WeakPolarHBondContact CD1-O 3.37Å; Q213-G218 WeakPolarHBondContact O-CA 3.39Å; Q213-G218 PolarHBondContact O-N 3.45Å; G218-I221 WeakPolarHBondContact CA-O 3.33Å
219	R	66.3	Low	78.8	Confident	142 Å²	142	41.4 Å²	41.4	54%	0.536	18%	0.182	S	C	.	.	S	Bend	trans	-72.2	-44.4	-174.7	-66.9	-179.4	-178.5	175.6	-1.8	112.3	Y5	Y5-R219 WeakPolarHBondContact CD2-O 3.23Å; Y5-R219 WeakPolarHBondContact CE2-O 3.47Å
220	E	66.8	Low	78.4	Confident	50 Å²	50	42 Å²	42	23%	0.234	18%	0.184	C	C	.	.	S	Bend	trans	-86.8	-39.5	175.3	-83.4	-161.2	144.9	0	0	113.1	K4 Y5 D159 V161	K4-E220 WeakPolarHBondContact CA-O 3.42Å; K4-E220 WeakPolarHBondContact CE-OE1 3.36Å; K4-E220 IonicContact NZ-OE1 2.82Å; Y5-E220 PolarHBondContact N-O 3.28Å; D159-E220 PolarHBondContact OD2-N 2.96Å; V161-E220 HydrophobicContact CG1-CB 4.09Å
221	I	71.2	Confident	78.3	Confident	22 Å²	22	41.4 Å²	41.4	11%	0.113	18%	0.18	C	C	.	.			trans	-133.1	132.2	-167	-68.3	-178.9	0	0	0	110.2	L2 V161 I214 G218	L2-I221 HydrophobicContact CB-CB 4.18Å; L2-I221 HydrophobicContact CB-CD1 3.71Å; L2-I221 HydrophobicContact CB-CG1 3.89Å; L2-I221 HydrophobicContact CB-CG2 3.35Å; L2-I221 HydrophobicContact CD1-CD1 4.03Å; L2-I221 HydrophobicContact CD1-CG2 3.78Å; L2-I221 HydrophobicContact CD2-CG2 3.08Å; L2-I221 HydrophobicContact CG-CD1 4.38Å; L2-I221 HydrophobicContact CG-CG2 3.47Å; L2-I221 VanDerWaalsContact CG-CG2 3.47Å; V161-I221 HydrophobicContact CG1-CB 3.55Å; V161-I221 HydrophobicContact CG1-CD1 3.4Å; V161-I221 VanDerWaalsContact CG1-CD1 3.4Å; V161-I221 HydrophobicContact CG1-CG1 3.51Å; I214-I221 HydrophobicContact CD1-CG2 4.1Å; I214-I221 HydrophobicContact CG1-CG2 4.03Å; I214-I221 HydrophobicContact CG2-CG2 4.03Å; G218-I221 WeakPolarHBondContact CA-O 3.33Å
222	Y	77.1	Confident	78.2	Confident	30 Å²	30	41 Å²	41	12%	0.118	18%	0.179	C	C	.	.			trans	-144	151	177.2	65.6	-84	0	0	0	112.5	Y5	Y5-Y222 HydrophobicContact CE2-CD1 4.37Å; Y5-Y222 HydrophobicContact CE2-CE1 4.31Å
223	Y	76.6	Confident	78.1	Confident	7 Å²	7	41.3 Å²	41.3	3%	0.027	18%	0.18	C	C	.	.			trans	-72.7	136.6	166.6	-67.1	-64	0	0	0	111.5	R39 F42 I214 L215 D227 F230 A231 I234	R39-Y223 PolarHBondContact NH1-O 3.14Å; F42-Y223 HydrophobicContact CZ-CG 4.46Å; I214-Y223 HydrophobicContact CB-CD2 4.47Å; I214-Y223 HydrophobicContact CB-CE2 4.15Å; I214-Y223 HydrophobicContact CG2-CD2 3.53Å; I214-Y223 HydrophobicContact CG2-CE1 4.43Å; I214-Y223 HydrophobicContact CG2-CE2 3.44Å; I214-Y223 VanDerWaalsContact CG2-CE2 3.44Å; I214-Y223 HydrophobicContact CG2-CG 4.1Å; L215-Y223 HydrophobicContact CD2-CD2 3.81Å; L215-Y223 HydrophobicContact CD2-CE2 3.88Å; L215-Y223 HydrophobicContact CG-CD2 4.24Å; L215-Y223 HydrophobicContact CG-CE2 4.03Å; Y223-D227 HydrophobicContact CD1-CB 4.11Å; Y223-F230 HydrophobicContact CD1-CD1 4.37Å; Y223-F230 AromaticContact CE1-CD1 3.71Å; Y223-F230 HydrophobicContact CE1-CD1 3.71Å; Y223-F230 HydrophobicContact CE1-CE1 4.02Å; Y223-A231 HydrophobicContact CD1-CB 4.13Å; Y223-A231 HydrophobicContact CD2-CB 3.82Å; Y223-A231 HydrophobicContact CE1-CB 4.17Å; Y223-A231 HydrophobicContact CE2-CB 3.84Å; Y223-A231 HydrophobicContact CG-CB 3.97Å; Y223-I234 HydrophobicContact CE1-CD1 4.36Å; Y223-I234 WeakPolarHBondContact OH-CD1 3.4Å
224	R	73.2	Confident	78.2	Confident	103 Å²	103	43 Å²	43	39%	0.389	19%	0.189	S	C	.	.			trans	-73.4	160.9	163.4	-59.3	177.7	175.8	-164.2	-1	109	H3 E226 D227	H3-R224 PolarHBondContact CD2-NH2 2.67Å; H3-R224 PolarHBondContact NE2-NH2 3.06Å; R224-E226 PolarHBondContact O-N 3.04Å; R224-D227 VanDerWaalsContact CB-OD2 3.29Å; R224-D227 WeakPolarHBondContact CB-OD2 3.44Å; R224-D227 PolarHBondContact N-OD2 3.42Å; R224-D227 PolarHBondContact O-N 3.4Å; R224-D227 VanDerWaalsContact O-N 3.09Å
225	R	70.8	Confident	78.4	Confident	125 Å²	125	42.7 Å²	42.7	47%	0.472	19%	0.187	S	C	.	.	G	3₁₀ helix	trans	-61.4	-29.2	176.6	-71.8	-171.4	-172.9	140.4	16.8	113.1	K38 D227	K38-R225 VanDerWaalsContact CB-NH2 3.3Å; R225-D227 VanDerWaalsContact C-N 3.29Å
226	E	71.2	Confident	78.5	Confident	135 Å²	135	42.8 Å²	42.8	63%	0.631	19%	0.188	S	C	*	.	G	3₁₀ helix	trans	-69.5	-29.7	178.3	-63.4	168.9	176.1	0	0	111.6	R224 F228	R224-E226 PolarHBondContact O-N 3.04Å; E226-F228 PolarHBondContact O-N 3.39Å
227	D	77.4	Confident	78.9	Confident	38 Å²	38	43.7 Å²	43.7	20%	0.203	19%	0.194	C	C	.	.	G	3₁₀ helix	trans	-80.4	20.6	-178.4	-52.7	-40.1	0	0	0	112.8	Y223 R224 R225 I229 F230 A231	Y223-D227 HydrophobicContact CD1-CB 4.11Å; R224-D227 VanDerWaalsContact CB-OD2 3.29Å; R224-D227 WeakPolarHBondContact CB-OD2 3.44Å; R224-D227 PolarHBondContact N-OD2 3.42Å; R224-D227 PolarHBondContact O-N 3.4Å; R224-D227 VanDerWaalsContact O-N 3.09Å; R225-D227 VanDerWaalsContact C-N 3.29Å; D227-I229 VanDerWaalsContact C-N 3.29Å; D227-I229 PolarHBondContact O-N 3.43Å; D227-F230 PolarHBondContact O-N 3.14Å; D227-A231 WeakPolarHBondContact O-CB 3.4Å; D227-A231 PolarHBondContact O-N 3.06Å
228	F	83.9	Confident	79.9	Confident	29 Å²	29	43.9 Å²	43.9	13%	0.127	19%	0.191	C	C	.	.	H	α-helix	trans	-58.6	-41.5	-178	126.3	-99	0	0	0	111.8	F42 K45 V46 T49 E226 A231 S232	F42-F228 HydrophobicContact CD2-CB 4.22Å; F42-F228 HydrophobicContact CE2-CB 3.62Å; F42-F228 HydrophobicContact CZ-CB 4.4Å; K45-F228 HydrophobicContact CD-CD2 3.98Å; K45-F228 HydrophobicContact CD-CE2 4.13Å; K45-F228 HydrophobicContact CD-CG 4.26Å; K45-F228 HydrophobicContact CG-CD2 4.06Å; K45-F228 HydrophobicContact CG-CE2 3.99Å; V46-F228 HydrophobicContact CG2-CD2 4.4Å; T49-F228 HydrophobicContact CG2-CE2 4.47Å; E226-F228 PolarHBondContact O-N 3.39Å; F228-A231 PolarHBondContact O-N 2.89Å; F228-S232 PolarHBondContact O-N 2.87Å
229	I	84.4	Confident	81.2	Confident	13 Å²	13	44.2 Å²	44.2	7%	0.067	19%	0.191	C	C	.	.	H	α-helix	trans	-63.3	-49.1	-179	-64	177.8	0	0	0	109	I95 T108 D109 Y112 D227 A231 S232 M233	I95-I229 HydrophobicContact CG2-CG2 3.92Å; T108-I229 HydrophobicContact CG2-CD1 3.67Å; D109-I229 WeakPolarHBondContact OD1-CD1 3.41Å; Y112-I229 HydrophobicContact CD1-CG2 4.41Å; Y112-I229 HydrophobicContact CD2-CG2 3.46Å; Y112-I229 VanDerWaalsContact CD2-CG2 3.46Å; Y112-I229 HydrophobicContact CE2-CG2 3.93Å; Y112-I229 HydrophobicContact CG-CG2 3.71Å; D227-I229 VanDerWaalsContact C-N 3.29Å; D227-I229 PolarHBondContact O-N 3.43Å; I229-A231 PolarHBondContact O-N 3.27Å; I229-S232 WeakPolarHBondContact O-CB 3.34Å; I229-S232 PolarHBondContact O-N 3.02Å; I229-S232 VanDerWaalsContact O-N 3.13Å; I229-M233 HydrophobicContact CG2-CG 4.46Å; I229-M233 HydrophobicContact CG2-SD 4.25Å; I229-M233 WeakPolarHBondContact O-CG 3.49Å; I229-M233 PolarHBondContact O-N 3.37Å
230	F	84.2	Confident	82.2	Confident	39 Å²	39	38.2 Å²	38.2	17%	0.171	17%	0.17	C	C	.	.	H	α-helix	trans	-63.9	-39.4	179.1	-178.1	-108.9	0	0	0	113.2	F96 Y223 D227 S232 M233 I234	F96-F230 HydrophobicContact CB-CE2 4.5Å; F96-F230 AromaticContact CD2-CD2 3.98Å; F96-F230 HydrophobicContact CD2-CD2 3.98Å; F96-F230 HydrophobicContact CD2-CE1 4.49Å; F96-F230 AromaticContact CD2-CE2 3.47Å; F96-F230 HydrophobicContact CD2-CE2 3.47Å; F96-F230 VanDerWaalsContact CD2-CE2 3.47Å; F96-F230 AromaticContact CD2-CZ 3.76Å; F96-F230 HydrophobicContact CD2-CZ 3.76Å; F96-F230 HydrophobicContact CE2-CE1 4.47Å; F96-F230 HydrophobicContact CE2-CE2 4.12Å; F96-F230 AromaticContact CE2-CZ 3.91Å; F96-F230 HydrophobicContact CE2-CZ 3.91Å; F96-F230 HydrophobicContact CG-CE2 4.39Å; Y223-F230 HydrophobicContact CD1-CD1 4.37Å; Y223-F230 AromaticContact CE1-CD1 3.71Å; Y223-F230 HydrophobicContact CE1-CD1 3.71Å; Y223-F230 HydrophobicContact CE1-CE1 4.02Å; D227-F230 PolarHBondContact O-N 3.14Å; F230-S232 VanDerWaalsContact C-N 3.31Å; F230-S232 PolarHBondContact O-N 3.3Å; F230-M233 PolarHBondContact O-N 3.42Å; F230-I234 HydrophobicContact CD1-CD1 3.8Å; F230-I234 HydrophobicContact CE1-CD1 3.25Å; F230-I234 HydrophobicContact CE1-CG1 4.34Å; F230-I234 HydrophobicContact CE2-CD1 4.04Å; F230-I234 HydrophobicContact CE2-CG1 4.39Å; F230-I234 HydrophobicContact CG-CD1 4.4Å; F230-I234 HydrophobicContact CZ-CD1 3.4Å; F230-I234 VanDerWaalsContact CZ-CD1 3.4Å; F230-I234 HydrophobicContact CZ-CG1 4.21Å; F230-I234 WeakPolarHBondContact O-CG1 3.49Å; F230-I234 PolarHBondContact O-N 3.28Å
231	A	86.9	Confident	83.3	Confident	0 Å²	0	40.2 Å²	40.2	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-60.6	-42.1	172.6	0	0	0	0	0	111.6	F42 V46 L215 Y223 D227 F228 I229 I234 H235	F42-A231 HydrophobicContact CE1-CB 4.36Å; F42-A231 HydrophobicContact CZ-CB 3.93Å; V46-A231 HydrophobicContact CG2-CB 4.06Å; L215-A231 HydrophobicContact CD2-CB 3.92Å; Y223-A231 HydrophobicContact CD1-CB 4.13Å; Y223-A231 HydrophobicContact CD2-CB 3.82Å; Y223-A231 HydrophobicContact CE1-CB 4.17Å; Y223-A231 HydrophobicContact CE2-CB 3.84Å; Y223-A231 HydrophobicContact CG-CB 3.97Å; D227-A231 WeakPolarHBondContact O-CB 3.4Å; D227-A231 PolarHBondContact O-N 3.06Å; F228-A231 PolarHBondContact O-N 2.89Å; I229-A231 PolarHBondContact O-N 3.27Å; A231-I234 PolarHBondContact O-N 3.07Å; A231-H235 PolarHBondContact O-N 3.45Å
232	S	88.7	Confident	84.3	Confident	0 Å²	0	39.4 Å²	39.4	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-63.9	-41.7	174.6	-155.1	0	0	0	0	112.3	N50 Y112 F228 I229 F230 H235 L236	N50-S232 PolarHBondContact OD1-O 3.44Å; N50-S232 VanDerWaalsContact OD1-O 3.05Å; N50-S232 PolarHBondContact OD1-OG 3.36Å; Y112-S232 WeakPolarHBondContact OH-CB 3.46Å; Y112-S232 PolarHBondContact OH-OG 3.08Å; F228-S232 PolarHBondContact O-N 2.87Å; I229-S232 WeakPolarHBondContact O-CB 3.34Å; I229-S232 PolarHBondContact O-N 3.02Å; I229-S232 VanDerWaalsContact O-N 3.13Å; F230-S232 VanDerWaalsContact C-N 3.31Å; F230-S232 PolarHBondContact O-N 3.3Å; S232-H235 PolarHBondContact O-N 3.28Å; S232-L236 VanDerWaalsContact O-CB 3.29Å; S232-L236 WeakPolarHBondContact O-CB 3.07Å; S232-L236 PolarHBondContact O-N 2.84Å
233	M	87.9	Confident	85	Confident	5 Å²	5	38 Å²	38	3%	0.025	17%	0.169	C	C	.	.	H	α-helix	trans	-62.3	-44.1	177.4	-69.3	-178.1	76.4	0	0	112.5	T92 I95 Y112 F115 I229 F230 L236 F237	T92-M233 HydrophobicContact CG2-CE 3.99Å; I95-M233 HydrophobicContact CB-SD 4Å; I95-M233 HydrophobicContact CD1-CE 3.78Å; I95-M233 HydrophobicContact CD1-SD 3.65Å; I95-M233 HydrophobicContact CG1-SD 4.43Å; I95-M233 HydrophobicContact CG2-SD 3.6Å; Y112-M233 HydrophobicContact CD2-CG 3.85Å; Y112-M233 HydrophobicContact CD2-SD 4.18Å; Y112-M233 HydrophobicContact CE2-CG 3.5Å; Y112-M233 HydrophobicContact CE2-SD 4.42Å; F115-M233 HydrophobicContact CD1-CE 3.91Å; F115-M233 HydrophobicContact CD1-CG 4.42Å; F115-M233 HydrophobicContact CD2-CE 3.79Å; F115-M233 HydrophobicContact CE1-CE 3.85Å; F115-M233 HydrophobicContact CE1-CG 4.18Å; F115-M233 HydrophobicContact CE2-CE 3.73Å; F115-M233 HydrophobicContact CG-CE 3.88Å; F115-M233 HydrophobicContact CZ-CE 3.76Å; I229-M233 HydrophobicContact CG2-CG 4.46Å; I229-M233 HydrophobicContact CG2-SD 4.25Å; I229-M233 WeakPolarHBondContact O-CG 3.49Å; I229-M233 PolarHBondContact O-N 3.37Å; F230-M233 PolarHBondContact O-N 3.42Å; M233-L236 PolarHBondContact O-N 2.83Å; M233-F237 VanDerWaalsContact O-CB 3.29Å; M233-F237 WeakPolarHBondContact O-CB 3.36Å; M233-F237 PolarHBondContact O-N 3.37Å
234	I	87.7	Confident	85.6	Confident	51 Å²	51	38.6 Å²	38.6	26%	0.262	17%	0.174	S	C	.	.	H	α-helix	trans	-63.3	-45.4	177.5	-72.3	173.1	0	0	0	110.3	E211 Y223 F230 A231 L236 F237 L238	E211-I234 HydrophobicContact CG-CG2 4.05Å; Y223-I234 HydrophobicContact CE1-CD1 4.36Å; Y223-I234 WeakPolarHBondContact OH-CD1 3.4Å; F230-I234 HydrophobicContact CD1-CD1 3.8Å; F230-I234 HydrophobicContact CE1-CD1 3.25Å; F230-I234 HydrophobicContact CE1-CG1 4.34Å; F230-I234 HydrophobicContact CE2-CD1 4.04Å; F230-I234 HydrophobicContact CE2-CG1 4.39Å; F230-I234 HydrophobicContact CG-CD1 4.4Å; F230-I234 HydrophobicContact CZ-CD1 3.4Å; F230-I234 VanDerWaalsContact CZ-CD1 3.4Å; F230-I234 HydrophobicContact CZ-CG1 4.21Å; F230-I234 WeakPolarHBondContact O-CG1 3.49Å; F230-I234 PolarHBondContact O-N 3.28Å; A231-I234 PolarHBondContact O-N 3.07Å; I234-L236 PolarHBondContact O-N 3.47Å; I234-F237 WeakPolarHBondContact O-CB 3.14Å; I234-F237 PolarHBondContact O-N 2.89Å; I234-L238 HydrophobicContact CG2-CD1 4.19Å; I234-L238 WeakPolarHBondContact O-CG 3.27Å; I234-L238 PolarHBondContact O-N 2.98Å
235	H	91	Very high	86.3	Confident	4 Å²	4	33.7 Å²	33.7	2%	0.019	16%	0.156	C	C	.	.	H	α-helix	trans	-62.2	-46.3	179.1	-163.4	70.4	0	0	0	111.5	V46 F47 N50 S146 E211 A231 S232 F237 L238 L239	V46-H235 HydrophobicContact CG1-CB 4.36Å; F47-H235 AromaticContact CE1-NE2 3.62Å; F47-H235 AromaticContact CZ-CE1 3.96Å; F47-H235 AromaticContact CZ-NE2 3.99Å; N50-H235 VanDerWaalsContact ND2-CB 3.34Å; N50-H235 WeakPolarHBondContact ND2-CB 3Å; N50-H235 PolarHBondContact ND2-CD2 3.39Å; S146-H235 PolarHBondContact OG-CE1 2.96Å; S146-H235 PolarHBondContact OG-NE2 2.89Å; E211-H235 WeakPolarHBondContact OE1-CA 3.43Å; E211-H235 WeakPolarHBondContact OE1-CB 3.37Å; E211-H235 IonicContact OE1-CG 2.72Å; E211-H235 PolarHBondContact OE1-N 3.45Å; E211-H235 VanDerWaalsContact OE1-N 3.14Å; E211-H235 IonicContact OE1-ND1 3.63Å; E211-H235 PolarHBondContact OE1-ND1 3.41Å; E211-H235 IonicContact OE2-CE1 3.54Å; E211-H235 IonicContact OE2-CG 3.22Å; E211-H235 IonicContact OE2-ND1 3.68Å; E211-H235 PolarHBondContact OE2-ND1 2.88Å; A231-H235 PolarHBondContact O-N 3.45Å; S232-H235 PolarHBondContact O-N 3.28Å; H235-F237 VanDerWaalsContact C-N 3.3Å; H235-F237 PolarHBondContact O-N 2.91Å; H235-L238 PolarHBondContact O-N 2.78Å; H235-L239 WeakPolarHBondContact O-CB 2.79Å; H235-L239 PolarHBondContact O-N 3.28Å
236	L	89.2	Confident	87.3	Confident	2 Å²	2	28.9 Å²	28.9	1%	0.01	14%	0.139	C	C	.	.	H	α-helix	trans	-59.8	-42.1	176.7	178.5	61.9	0	0	0	111.3	Q53 F115 F119 S232 M233 I234 L239 T240	Q53-L236 HydrophobicContact CB-CD1 4.25Å; Q53-L236 HydrophobicContact CB-CD2 4.35Å; F115-L236 HydrophobicContact CE1-CD2 3.8Å; F119-L236 HydrophobicContact CD1-CD1 4.25Å; F119-L236 HydrophobicContact CD1-CD2 3.7Å; F119-L236 HydrophobicContact CD1-CG 3.89Å; F119-L236 HydrophobicContact CE1-CD1 3.91Å; F119-L236 HydrophobicContact CE1-CD2 3.87Å; F119-L236 HydrophobicContact CE1-CG 3.52Å; F119-L236 HydrophobicContact CG-CD2 4.47Å; F119-L236 HydrophobicContact CZ-CG 4.36Å; S232-L236 VanDerWaalsContact O-CB 3.29Å; S232-L236 WeakPolarHBondContact O-CB 3.07Å; S232-L236 PolarHBondContact O-N 2.84Å; M233-L236 PolarHBondContact O-N 2.83Å; I234-L236 PolarHBondContact O-N 3.47Å; L236-L239 PolarHBondContact O-N 3.37Å; L236-T240 PolarHBondContact O-N 3.18Å; L236-T240 PolarHBondContact O-OG1 3.5Å
237	F	88	Confident	88.2	Confident	101 Å²	101	22.6 Å²	22.6	44%	0.443	11%	0.109	S	C	.	.	H	α-helix	trans	-59.1	-48.5	176.2	179.9	-92.5	0	0	0	111.8	M233 I234 H235 L239 T240 F241	M233-F237 VanDerWaalsContact O-CB 3.29Å; M233-F237 WeakPolarHBondContact O-CB 3.36Å; M233-F237 PolarHBondContact O-N 3.37Å; I234-F237 WeakPolarHBondContact O-CB 3.14Å; I234-F237 PolarHBondContact O-N 2.89Å; H235-F237 VanDerWaalsContact C-N 3.3Å; H235-F237 PolarHBondContact O-N 2.91Å; F237-L239 VanDerWaalsContact C-N 3.32Å; F237-L239 PolarHBondContact O-N 3.07Å; F237-T240 PolarHBondContact O-N 2.8Å; F237-F241 HydrophobicContact CD1-CD2 4.03Å; F237-F241 HydrophobicContact CD1-CE2 4.41Å; F237-F241 HydrophobicContact CD2-CD2 4.14Å; F237-F241 HydrophobicContact CD2-CE2 4.07Å; F237-F241 AromaticContact CE1-CD2 3.63Å; F237-F241 HydrophobicContact CE1-CD2 3.63Å; F237-F241 AromaticContact CE1-CE2 3.69Å; F237-F241 HydrophobicContact CE1-CE2 3.69Å; F237-F241 HydrophobicContact CE1-CG 4.36Å; F237-F241 HydrophobicContact CE1-CZ 4.42Å; F237-F241 AromaticContact CE2-CD2 3.78Å; F237-F241 HydrophobicContact CE2-CD2 3.78Å; F237-F241 AromaticContact CE2-CE2 3.29Å; F237-F241 HydrophobicContact CE2-CE2 3.29Å; F237-F241 HydrophobicContact CE2-CZ 4.27Å; F237-F241 HydrophobicContact CG-CD2 4.27Å; F237-F241 AromaticContact CZ-CD2 3.51Å; F237-F241 HydrophobicContact CZ-CD2 3.51Å; F237-F241 AromaticContact CZ-CE2 3.06Å; F237-F241 HydrophobicContact CZ-CE2 3.06Å; F237-F241 AromaticContact CZ-CZ 3.76Å; F237-F241 HydrophobicContact CZ-CZ 3.76Å; F237-F241 WeakPolarHBondContact O-CB 3.36Å; F237-F241 PolarHBondContact O-N 3.36Å
238	L	91.3	Very high	88.6	Confident	19 Å²	19	22.6 Å²	22.6	10%	0.099	11%	0.109	C	C	.	.	H	α-helix	trans	-62.7	-39.9	177.6	-68.8	173.8	0	0	0	112	A207 E211 I234 H235 F241 S242	A207-L238 HydrophobicContact CB-CD2 3.59Å; E211-L238 HydrophobicContact CB-CD1 3.92Å; E211-L238 HydrophobicContact CG-CD1 4.15Å; E211-L238 WeakPolarHBondContact OE2-CD1 3.45Å; I234-L238 HydrophobicContact CG2-CD1 4.19Å; I234-L238 WeakPolarHBondContact O-CG 3.27Å; I234-L238 PolarHBondContact O-N 2.98Å; H235-L238 PolarHBondContact O-N 2.78Å; L238-F241 PolarHBondContact O-N 3.2Å; L238-S242 WeakPolarHBondContact O-CB 3.26Å; L238-S242 PolarHBondContact O-N 2.94Å
239	L	91.5	Very high	88.7	Confident	14 Å²	14	23.4 Å²	23.4	7%	0.073	11%	0.114	C	C	.	.	H	α-helix	trans	-65.2	-42.2	179.8	-148.4	138.7	0	0	0	111	V54 W139 T142 H235 L236 F237 S242 Y243	V54-L239 HydrophobicContact CG2-CD2 3.79Å; W139-L239 HydrophobicContact CE3-CD2 4.27Å; W139-L239 HydrophobicContact CZ3-CD2 3.57Å; T142-L239 HydrophobicContact CG2-CD2 3.56Å; T142-L239 HydrophobicContact CG2-CG 3.75Å; T142-L239 WeakPolarHBondContact CG2-O 3.28Å; H235-L239 WeakPolarHBondContact O-CB 2.79Å; H235-L239 PolarHBondContact O-N 3.28Å; L236-L239 PolarHBondContact O-N 3.37Å; F237-L239 VanDerWaalsContact C-N 3.32Å; F237-L239 PolarHBondContact O-N 3.07Å; L239-S242 WeakPolarHBondContact O-CB 3.41Å; L239-S242 PolarHBondContact O-N 3.01Å; L239-Y243 PolarHBondContact O-N 3.48Å
240	T	87.8	Confident	88.8	Confident	16 Å²	16	24.3 Å²	24.3	10%	0.098	12%	0.117	C	C	.	.	H	α-helix	trans	-73	-34.9	176.8	-66.9	0	0	0	0	113.6	F119 I123 L236 F237 S242 Y243 S244	F119-T240 HydrophobicContact CE1-CG2 3.85Å; F119-T240 WeakPolarHBondContact CE1-OG1 3.35Å; F119-T240 HydrophobicContact CE2-CG2 4.43Å; F119-T240 VanDerWaalsContact CZ-CB 3.43Å; F119-T240 HydrophobicContact CZ-CG2 3.6Å; F119-T240 WeakPolarHBondContact CZ-OG1 3.25Å; I123-T240 HydrophobicContact CD1-CG2 3.93Å; I123-T240 WeakPolarHBondContact CD1-OG1 3.45Å; I123-T240 HydrophobicContact CG1-CG2 3.69Å; L236-T240 PolarHBondContact O-N 3.18Å; L236-T240 PolarHBondContact O-OG1 3.5Å; F237-T240 PolarHBondContact O-N 2.8Å; T240-S242 PolarHBondContact O-N 3.3Å; T240-Y243 WeakPolarHBondContact O-CB 3.32Å; T240-Y243 PolarHBondContact O-N 3.12Å; T240-S244 PolarHBondContact O-N 2.96Å
241	F	89.2	Confident	88.6	Confident	91 Å²	91	25 Å²	25	40%	0.399	12%	0.123	S	C	.	.	H	α-helix	trans	-61.1	-37.9	169.9	-100.9	-95	0	0	0	110.4	V200 I204 F237 L238 S244 G245	V200-F241 HydrophobicContact CG1-CD1 4.29Å; V200-F241 WeakPolarHBondContact CG1-O 3.06Å; I204-F241 HydrophobicContact CD1-CB 3.49Å; I204-F241 VanDerWaalsContact CD1-CB 3.49Å; I204-F241 WeakPolarHBondContact CD1-O 3.43Å; I204-F241 HydrophobicContact CG1-CB 4.07Å; F237-F241 HydrophobicContact CD1-CD2 4.03Å; F237-F241 HydrophobicContact CD1-CE2 4.41Å; F237-F241 HydrophobicContact CD2-CD2 4.14Å; F237-F241 HydrophobicContact CD2-CE2 4.07Å; F237-F241 AromaticContact CE1-CD2 3.63Å; F237-F241 HydrophobicContact CE1-CD2 3.63Å; F237-F241 AromaticContact CE1-CE2 3.69Å; F237-F241 HydrophobicContact CE1-CE2 3.69Å; F237-F241 HydrophobicContact CE1-CG 4.36Å; F237-F241 HydrophobicContact CE1-CZ 4.42Å; F237-F241 AromaticContact CE2-CD2 3.78Å; F237-F241 HydrophobicContact CE2-CD2 3.78Å; F237-F241 AromaticContact CE2-CE2 3.29Å; F237-F241 HydrophobicContact CE2-CE2 3.29Å; F237-F241 HydrophobicContact CE2-CZ 4.27Å; F237-F241 HydrophobicContact CG-CD2 4.27Å; F237-F241 AromaticContact CZ-CD2 3.51Å; F237-F241 HydrophobicContact CZ-CD2 3.51Å; F237-F241 AromaticContact CZ-CE2 3.06Å; F237-F241 HydrophobicContact CZ-CE2 3.06Å; F237-F241 AromaticContact CZ-CZ 3.76Å; F237-F241 HydrophobicContact CZ-CZ 3.76Å; F237-F241 WeakPolarHBondContact O-CB 3.36Å; F237-F241 PolarHBondContact O-N 3.36Å; L238-F241 PolarHBondContact O-N 3.2Å; F241-S244 PolarHBondContact O-N 3.33Å; F241-S244 PolarHBondContact O-OG 2.85Å; F241-G245 PolarHBondContact O-N 3.13Å
242	S	92.6	Very high	87.9	Confident	5 Å²	5	28.3 Å²	28.3	4%	0.035	14%	0.14	C	C	.	.	H	α-helix	trans	-67.8	-43.5	178.3	177	0	0	0	0	110.3	L238 L239 T240 S244 G245 F246	L238-S242 WeakPolarHBondContact O-CB 3.26Å; L238-S242 PolarHBondContact O-N 2.94Å; L239-S242 WeakPolarHBondContact O-CB 3.41Å; L239-S242 PolarHBondContact O-N 3.01Å; T240-S242 PolarHBondContact O-N 3.3Å; S242-S244 VanDerWaalsContact C-N 3.3Å; S242-S244 PolarHBondContact O-N 3.46Å; S242-G245 PolarHBondContact O-N 3.43Å; S242-G245 VanDerWaalsContact O-N 3.15Å; S242-F246 WeakPolarHBondContact O-CD2 3.38Å; S242-F246 PolarHBondContact O-N 2.86Å; S242-F246 VanDerWaalsContact O-N 3.14Å
243	Y	91.6	Very high	87.2	Confident	0 Å²	0	30.8 Å²	30.8	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-55.6	-45.7	172.2	175.3	-101.4	0	0	0	111.9	I123 L126 S127 I135 W139 T142 L239 T240 G245 F246 I247	I123-Y243 HydrophobicContact CG2-CD1 4.02Å; I123-Y243 HydrophobicContact CG2-CE1 3.61Å; L126-Y243 HydrophobicContact CD2-CD1 4.22Å; L126-Y243 HydrophobicContact CD2-CE1 4.09Å; S127-Y243 PolarHBondContact OG-OH 3.35Å; I135-Y243 WeakPolarHBondContact CG2-OH 3.39Å; W139-Y243 AromaticContact CD1-CE2 3.43Å; W139-Y243 VanDerWaalsContact CD1-CE2 3.43Å; W139-Y243 AromaticContact CD2-CD2 3.73Å; W139-Y243 HydrophobicContact CD2-CD2 3.73Å; W139-Y243 AromaticContact CD2-CE2 3.91Å; W139-Y243 HydrophobicContact CD2-CE2 3.91Å; W139-Y243 HydrophobicContact CD2-CG 4.46Å; W139-Y243 AromaticContact CE2-CD2 3.84Å; W139-Y243 AromaticContact CE2-CE2 3.76Å; W139-Y243 HydrophobicContact CE3-CD2 4.18Å; W139-Y243 AromaticContact CG-CD2 3.94Å; W139-Y243 HydrophobicContact CG-CD2 3.94Å; W139-Y243 AromaticContact CG-CE2 3.77Å; W139-Y243 HydrophobicContact CG-CE2 3.77Å; W139-Y243 HydrophobicContact CZ2-CD2 4.44Å; W139-Y243 AromaticContact NE1-CD2 3.97Å; W139-Y243 AromaticContact NE1-CE2 3.4Å; W139-Y243 AromaticContact NE1-CZ 3.7Å; T142-Y243 VanDerWaalsContact OG1-CA 3.26Å; T142-Y243 WeakPolarHBondContact OG1-CA 3.38Å; T142-Y243 PolarHBondContact OG1-N 3.26Å; L239-Y243 PolarHBondContact O-N 3.48Å; T240-Y243 WeakPolarHBondContact O-CB 3.32Å; T240-Y243 PolarHBondContact O-N 3.12Å; Y243-G245 VanDerWaalsContact C-N 3.31Å; Y243-G245 PolarHBondContact O-N 2.9Å; Y243-F246 PolarHBondContact O-N 2.77Å; Y243-I247 HydrophobicContact CD1-CG1 4.09Å; Y243-I247 HydrophobicContact CD2-CG1 4.34Å; Y243-I247 HydrophobicContact CE1-CD1 4.24Å; Y243-I247 HydrophobicContact CE1-CG1 3.6Å; Y243-I247 HydrophobicContact CE2-CD1 4.08Å; Y243-I247 HydrophobicContact CE2-CG1 3.88Å; Y243-I247 HydrophobicContact CG-CG1 4.44Å; Y243-I247 VanDerWaalsContact CZ-CG1 3.48Å; Y243-I247 WeakPolarHBondContact O-CG1 3.21Å; Y243-I247 PolarHBondContact O-N 2.97Å; Y243-I247 WeakPolarHBondContact OH-CD1 3.43Å
244	S	89.1	Confident	86	Confident	20 Å²	20	36.2 Å²	36.2	14%	0.14	18%	0.182	C	C	.	.	H	α-helix	trans	-62.5	-37.2	177.5	77.8	0	0	0	0	112.7	T240 F241 S242 F246 I247 L248	T240-S244 PolarHBondContact O-N 2.96Å; F241-S244 PolarHBondContact O-N 3.33Å; F241-S244 PolarHBondContact O-OG 2.85Å; S242-S244 VanDerWaalsContact C-N 3.3Å; S242-S244 PolarHBondContact O-N 3.46Å; S244-F246 PolarHBondContact O-N 3.25Å; S244-I247 PolarHBondContact O-N 3.23Å; S244-L248 WeakPolarHBondContact O-CB 3.38Å; S244-L248 WeakPolarHBondContact O-CD1 3.46Å; S244-L248 VanDerWaalsContact O-CG 3.27Å; S244-L248 WeakPolarHBondContact O-CG 3.43Å; S244-L248 PolarHBondContact O-N 3.07Å
245	G	88.9	Confident	84.6	Confident	0 Å²	0	38.6 Å²	38.6	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-59.3	-45.7	174.4	0	0	0	0	0	112.1	G197 F241 S242 Y243 M249	G197-G245 WeakPolarHBondContact CA-O 3.46Å; F241-G245 PolarHBondContact O-N 3.13Å; S242-G245 PolarHBondContact O-N 3.43Å; S242-G245 VanDerWaalsContact O-N 3.15Å; Y243-G245 VanDerWaalsContact C-N 3.31Å; Y243-G245 PolarHBondContact O-N 2.9Å; G245-M249 WeakPolarHBondContact O-CG 3.26Å; G245-M249 PolarHBondContact O-N 2.95Å
246	F	91.4	Very high	82.4	Confident	25 Å²	25	47.5 Å²	47.5	11%	0.11	25%	0.25	C	C	.	.	H	α-helix	trans	-68.2	-42.5	176.3	-71.3	-63.2	0	0	0	112.9	L141 T142 L145 L201 S242 Y243 S244 L248 M249 F250	L141-F246 HydrophobicContact CB-CD1 4.22Å; L141-F246 HydrophobicContact CB-CD2 4.12Å; L141-F246 HydrophobicContact CB-CE1 3.97Å; L141-F246 HydrophobicContact CB-CE2 3.85Å; L141-F246 HydrophobicContact CB-CG 4.29Å; L141-F246 HydrophobicContact CB-CZ 3.78Å; L141-F246 HydrophobicContact CD1-CD1 3.9Å; L141-F246 HydrophobicContact CD1-CE1 3.99Å; L141-F246 HydrophobicContact CD1-CG 4.49Å; T142-F246 WeakPolarHBondContact OG1-CD2 3.36Å; L145-F246 HydrophobicContact CD2-CE2 4.1Å; L145-F246 HydrophobicContact CD2-CZ 4.06Å; L201-F246 HydrophobicContact CD1-CD1 4.28Å; L201-F246 HydrophobicContact CD1-CE1 3.88Å; L201-F246 HydrophobicContact CD1-CZ 4.03Å; L201-F246 HydrophobicContact CD2-CD2 4.43Å; L201-F246 HydrophobicContact CD2-CE2 4.12Å; L201-F246 HydrophobicContact CD2-CZ 4.33Å; S242-F246 WeakPolarHBondContact O-CD2 3.38Å; S242-F246 PolarHBondContact O-N 2.86Å; S242-F246 VanDerWaalsContact O-N 3.14Å; Y243-F246 PolarHBondContact O-N 2.77Å; S244-F246 PolarHBondContact O-N 3.25Å; F246-L248 VanDerWaalsContact C-N 3.29Å; F246-L248 PolarHBondContact O-N 2.95Å; F246-M249 WeakPolarHBondContact O-CB 3.42Å; F246-M249 PolarHBondContact O-N 3.03Å; F246-M249 VanDerWaalsContact O-N 3.07Å; F246-F250 HydrophobicContact CB-CE2 4.16Å; F246-F250 WeakPolarHBondContact O-CD2 3.44Å; F246-F250 WeakPolarHBondContact O-CG 3.18Å; F246-F250 PolarHBondContact O-N 3.16Å; F246-F250 VanDerWaalsContact O-N 3.12Å
247	I	88.9	Confident	82.1	Confident	3 Å²	3	49.8 Å²	49.8	2%	0.015	26%	0.262	C	S	.	.	H	α-helix	trans	-57.5	-43.4	176.1	-75.4	-67.5	0	0	0	111.4	L126 V130 I135 Y243 S244 M249 F250 L251	L126-I247 HydrophobicContact CD2-CB 4.09Å; L126-I247 HydrophobicContact CD2-CG1 4.28Å; L126-I247 HydrophobicContact CD2-CG2 3.82Å; L126-I247 HydrophobicContact CG-CG2 4.49Å; V130-I247 HydrophobicContact CB-CD1 4.32Å; V130-I247 HydrophobicContact CG2-CD1 3.98Å; V130-I247 HydrophobicContact CG2-CG2 3.72Å; I135-I247 HydrophobicContact CG1-CD1 4.43Å; Y243-I247 HydrophobicContact CD1-CG1 4.09Å; Y243-I247 HydrophobicContact CD2-CG1 4.34Å; Y243-I247 HydrophobicContact CE1-CD1 4.24Å; Y243-I247 HydrophobicContact CE1-CG1 3.6Å; Y243-I247 HydrophobicContact CE2-CD1 4.08Å; Y243-I247 HydrophobicContact CE2-CG1 3.88Å; Y243-I247 HydrophobicContact CG-CG1 4.44Å; Y243-I247 VanDerWaalsContact CZ-CG1 3.48Å; Y243-I247 WeakPolarHBondContact O-CG1 3.21Å; Y243-I247 PolarHBondContact O-N 2.97Å; Y243-I247 WeakPolarHBondContact OH-CD1 3.43Å; S244-I247 PolarHBondContact O-N 3.23Å; I247-M249 VanDerWaalsContact C-N 3.29Å; I247-M249 PolarHBondContact O-N 3.39Å; I247-F250 PolarHBondContact O-N 3.08Å; I247-F250 VanDerWaalsContact O-N 3.14Å; I247-L251 PolarHBondContact O-N 2.72Å
248	L	85.8	Confident	81.7	Confident	37 Å²	37	47.1 Å²	47.1	19%	0.194	25%	0.252	C	S	.	.	H	α-helix	trans	-63.9	-32.9	177	-74.5	164.9	0	0	0	112.9	I196 V200 S244 F246 F250 L251	I196-L248 HydrophobicContact CG2-CD1 4.1Å; V200-L248 HydrophobicContact CG2-CD1 4.32Å; S244-L248 WeakPolarHBondContact O-CB 3.38Å; S244-L248 WeakPolarHBondContact O-CD1 3.46Å; S244-L248 VanDerWaalsContact O-CG 3.27Å; S244-L248 WeakPolarHBondContact O-CG 3.43Å; S244-L248 PolarHBondContact O-N 3.07Å; F246-L248 VanDerWaalsContact C-N 3.29Å; F246-L248 PolarHBondContact O-N 2.95Å; L248-F250 VanDerWaalsContact C-N 3.35Å; L248-L251 HydrophobicContact CD2-CD1 4.3Å
249	M	86.8	Confident	81.2	Confident	46 Å²	46	48.7 Å²	48.7	23%	0.227	26%	0.261	C	S	.	.	H	α-helix	trans	-69.5	-32.3	174.4	-67.1	-178.8	75.4	0	0	112.4	P198 L201 G245 F246 I247	P198-M249 HydrophobicContact CG-CE 3.86Å; P198-M249 HydrophobicContact CG-CG 4.42Å; P198-M249 HydrophobicContact CG-SD 4Å; L201-M249 HydrophobicContact CD1-SD 4.21Å; G245-M249 WeakPolarHBondContact O-CG 3.26Å; G245-M249 PolarHBondContact O-N 2.95Å; F246-M249 WeakPolarHBondContact O-CB 3.42Å; F246-M249 PolarHBondContact O-N 3.03Å; F246-M249 VanDerWaalsContact O-N 3.07Å; I247-M249 VanDerWaalsContact C-N 3.29Å; I247-M249 PolarHBondContact O-N 3.39Å
250	F	86	Confident	80.6	Confident	33 Å²	33	50.7 Å²	50.7	15%	0.145	27%	0.272	C	S	.	.	H	α-helix	trans	-92	-6.2	-177.8	-58.7	-43.1	0	0	0	114.5	V130 F134 I137 S138 L141 F246 I247 L248 N252 I253	V130-F250 HydrophobicContact CG1-CB 4.06Å; F134-F250 HydrophobicContact CB-CB 4.01Å; F134-F250 HydrophobicContact CB-CD2 4.13Å; F134-F250 HydrophobicContact CB-CG 4.22Å; F134-F250 HydrophobicContact CD1-CB 4.18Å; F134-F250 HydrophobicContact CD1-CD1 4.09Å; F134-F250 HydrophobicContact CD1-CD2 4.29Å; F134-F250 AromaticContact CD1-CG 3.94Å; F134-F250 HydrophobicContact CD1-CG 3.94Å; F134-F250 HydrophobicContact CE1-CD1 4.49Å; F134-F250 HydrophobicContact CG-CB 4.08Å; F134-F250 HydrophobicContact CG-CG 4.27Å; I137-F250 HydrophobicContact CG2-CE2 4.19Å; I137-F250 HydrophobicContact CG2-CZ 4.17Å; S138-F250 WeakPolarHBondContact OG-CD2 3.41Å; S138-F250 WeakPolarHBondContact OG-CE2 3.38Å; L141-F250 HydrophobicContact CD1-CE2 4.18Å; L141-F250 HydrophobicContact CD1-CZ 3.86Å; F246-F250 HydrophobicContact CB-CE2 4.16Å; F246-F250 WeakPolarHBondContact O-CD2 3.44Å; F246-F250 WeakPolarHBondContact O-CG 3.18Å; F246-F250 PolarHBondContact O-N 3.16Å; F246-F250 VanDerWaalsContact O-N 3.12Å; I247-F250 PolarHBondContact O-N 3.08Å; I247-F250 VanDerWaalsContact O-N 3.14Å; L248-F250 VanDerWaalsContact C-N 3.35Å; F250-N252 PolarHBondContact O-N 3.21Å; F250-I253 HydrophobicContact CD1-CD1 3.65Å; F250-I253 HydrophobicContact CE1-CD1 4.4Å; F250-I253 PolarHBondContact O-N 3.02Å
251	L	80.4	Confident	80.1	Confident	54 Å²	54	52.9 Å²	52.9	28%	0.283	28%	0.282	S	S	.	.	T	Hydrogen-bonded Turn	trans	-58.3	-25.8	-170.7	-153.3	136.6	0	0	0	114.6	I247 L248	I247-L251 PolarHBondContact O-N 2.72Å; L248-L251 HydrophobicContact CD2-CD1 4.3Å
252	N	73.3	Confident	79.5	Confident	69 Å²	69	50.3 Å²	50.3	37%	0.369	28%	0.275	S	S	.	.	T	Hydrogen-bonded Turn	trans	-113.1	12.5	-179	-72.2	-25.9	0	0	0	113.8	T193 F250 N254	T193-N252 PolarHBondContact OG1-ND2 2.85Å; F250-N252 PolarHBondContact O-N 3.21Å; N252-N254 PolarHBondContact O-N 3.46Å
253	I	73.5	Confident	78.6	Confident	51 Å²	51	53.6 Å²	53.6	26%	0.262	29%	0.292	S	S	.	.			trans	-87.7	104.3	174.8	-55.7	-175.9	0	0	0	108.2	F134 W194 F250	F134-I253 HydrophobicContact CE1-CD1 4.46Å; F134-I253 HydrophobicContact CE1-CG2 4.24Å; F134-I253 HydrophobicContact CE2-CB 4.2Å; F134-I253 HydrophobicContact CE2-CG2 4.02Å; F134-I253 HydrophobicContact CZ-CB 4Å; F134-I253 HydrophobicContact CZ-CG2 3.49Å; F134-I253 VanDerWaalsContact CZ-CG2 3.49Å; W194-I253 HydrophobicContact CH2-CD1 3.65Å; W194-I253 HydrophobicContact CH2-CG1 3.85Å; W194-I253 HydrophobicContact CZ2-CD1 4.07Å; W194-I253 HydrophobicContact CZ2-CG1 3.71Å; F250-I253 HydrophobicContact CD1-CD1 3.65Å; F250-I253 HydrophobicContact CE1-CD1 4.4Å; F250-I253 PolarHBondContact O-N 3.02Å
254	N	62.1	Low	77.6	Confident	120 Å²	120	57.7 Å²	57.7	64%	0.642	31%	0.314	S	S	*	.			trans	-89.2	128.6	167.5	-80.8	-11.8	0	0	0	109.6	N252 T256	N252-N254 PolarHBondContact O-N 3.46Å; N254-T256 VanDerWaalsContact C-N 3.25Å; N254-T256 HydrophobicContact CB-CG2 4.27Å; N254-T256 PolarHBondContact O-N 2.73Å; N254-T256 VanDerWaalsContact O-N 3.13Å
255	L	58.7	Low	76.7	Confident	101 Å²	101	60.8 Å²	60.8	53%	0.529	33%	0.329	S	S	.	.			trans	-83.3	73.2	166.7	-68.6	170.4	0	0	0	108.6	E131 F134	E131-L255 WeakPolarHBondContact OE2-CD1 3.44Å; F134-L255 HydrophobicContact CE2-CD1 3.97Å; F134-L255 HydrophobicContact CE2-CG 3.99Å; F134-L255 HydrophobicContact CZ-CD1 4.12Å; F134-L255 HydrophobicContact CZ-CD2 4.23Å; F134-L255 HydrophobicContact CZ-CG 4.02Å
256	T	44.3	Very low	75.5	Confident	191 Å²	191	66.4 Å²	66.4	100%	1.172	36%	0.359	S	S	*	.			trans	-82.8	0	167.8	49.4	0	0	0	0	111.5	N254	N254-T256 VanDerWaalsContact C-N 3.25Å; N254-T256 HydrophobicContact CB-CG2 4.27Å; N254-T256 PolarHBondContact O-N 2.73Å; N254-T256 VanDerWaalsContact O-N 3.13Å

Retrieved 256 of 256 residues in 70.9 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).