A0A3Q0KK74_SCHMA Loading...

G_PROTEIN_RECEP_F1_2 domain-containing protein

AlphaFold DB , UniProt , Accession A0A3Q0KK74, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 490 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	46.7	Very low	52.2	Low	228 Å²	228	115.1 Å²	115.1	100%	1.123	61%	0.611	S	S	*	*				0	1	0	-104.2	176.3	173.5	0	0	115.5
2	K	39.1	Very low	54.1	Low	195 Å²	195	109.1 Å²	109.1	85%	0.848	58%	0.579	S	S	*	*			trans	-99	5.2	180	-99.3	179.8	176.9	178.5	0	116
3	S	50.1	Low	55.2	Low	95 Å²	95	110 Å²	110	66%	0.664	58%	0.584	S	S	*	*	S	Bend	trans	-108.9	-9.4	-178.9	87.5	0	0	0	0	115.5
4	I	51.7	Low	56.9	Low	121 Å²	121	109.7 Å²	109.7	62%	0.621	60%	0.596	S	S	*	*	H	α-helix	trans	-81.6	-30.4	178.1	-61.9	173.4	0	0	0	110.8	N6 L8	I4-N6 PolarHBondContact O-N 3.12Å; I4-L8 PolarHBondContact O-N 3.18Å
5	T	51	Low	58.6	Low	86 Å²	86	104.7 Å²	104.7	53%	0.528	57%	0.568	S	S	.	*	H	α-helix	trans	-72.8	-27.5	-177.2	49.9	0	0	0	0	113.8
6	N	47.1	Very low	60.5	Low	116 Å²	116	101.1 Å²	101.1	62%	0.62	55%	0.551	S	S	*	*	H	α-helix	trans	-84.9	-21.1	-177.6	-75.8	1.2	0	0	0	113.9	I4 S9	I4-N6 PolarHBondContact O-N 3.12Å; N6-S9 PolarHBondContact O-OG 3.11Å
7	Q	49.9	Very low	62.3	Low	161 Å²	161	102.9 Å²	102.9	75%	0.752	56%	0.559	S	S	*	*	H	α-helix	trans	-79.1	-28.3	168.4	-99.1	-178.4	-31.1	0	0	111.8	S9 N10	Q7-S9 PolarHBondContact O-N 3.41Å; Q7-N10 PolarHBondContact O-N 2.81Å
8	L	52.1	Low	63.9	Low	53 Å²	53	99.4 Å²	99.4	28%	0.277	54%	0.539	S	S	.	.	H	α-helix	trans	-66.3	-38.5	-177.2	-153.9	79.8	0	0	0	112.8	I4 N10 N93 L95	I4-L8 PolarHBondContact O-N 3.18Å; L8-N10 VanDerWaalsContact C-N 3.34Å; L8-N10 PolarHBondContact O-N 3.39Å; L8-N93 VanDerWaalsContact CD1-O 3.22Å; L8-N93 WeakPolarHBondContact CD1-O 3.26Å; L8-N93 HydrophobicContact CD2-CB 4.45Å; L8-N93 VanDerWaalsContact CG-O 3.26Å; L8-N93 WeakPolarHBondContact CG-O 3.19Å; L8-L95 HydrophobicContact CD1-CD2 3.48Å; L8-L95 VanDerWaalsContact CD1-CD2 3.48Å; L8-L95 HydrophobicContact CD1-CG 3.91Å; L8-L95 HydrophobicContact CD2-CD2 4.03Å; L8-L95 HydrophobicContact CD2-CG 4.27Å; L8-L95 HydrophobicContact CG-CD2 4.42Å
9	S	52.4	Low	65.3	Low	59 Å²	59	95.1 Å²	95.1	41%	0.413	52%	0.515	S	S	.	.	H	α-helix	trans	-69	-31.4	178.7	57.8	0	0	0	0	112.8	N6 Q7 C11 N13	N6-S9 PolarHBondContact O-OG 3.11Å; Q7-S9 PolarHBondContact O-N 3.41Å; S9-C11 VanDerWaalsContact C-N 3.3Å; S9-C11 PolarHBondContact O-N 3.33Å; S9-N13 PolarHBondContact O-ND2 3.37Å; S9-N13 PolarHBondContact O-OD1 3.46Å
10	N	62	Low	66.7	Low	106 Å²	106	93 Å²	93	57%	0.567	50%	0.503	S	S	*	.	H	α-helix	trans	-73.2	-19.1	-174.1	-75	-13.8	0	0	0	114.3	Q7 L8 L12	Q7-N10 PolarHBondContact O-N 2.81Å; L8-N10 VanDerWaalsContact C-N 3.34Å; L8-N10 PolarHBondContact O-N 3.39Å; N10-L12 PolarHBondContact O-N 3.16Å
11	C	71.7	Confident	68	Low	46 Å²	46	93.6 Å²	93.6	31%	0.311	50%	0.504	S	S	.	.	T	Hydrogen-bonded Turn	trans	-63.3	-28.6	-179.8	-169.5	0	0	0	0	112.7	S9 C94	S9-C11 VanDerWaalsContact C-N 3.3Å; S9-C11 PolarHBondContact O-N 3.33Å; C11-C94 HydrophobicContact CB-CB 3.67Å; C11-C94 WeakPolarHBondContact CB-SG 3.38Å; C11-C94 WeakPolarHBondContact SG-CB 3.34Å; C11-C94 CovalentContact SG-SG 2.04Å; C11-C94 PolarHBondContact SG-SG 3.34Å
12	L	75	Confident	70.3	Confident	43 Å²	43	82.8 Å²	82.8	23%	0.225	45%	0.45	C	S	.	.	T	Hydrogen-bonded Turn	trans	-111.2	-9.8	-171.8	-50.6	-174.5	0	0	0	114.1	N10 S14 L15 W90	N10-L12 PolarHBondContact O-N 3.16Å; L12-S14 PolarHBondContact O-N 3.15Å; L12-S14 VanDerWaalsContact O-N 3.15Å; L12-L15 HydrophobicContact CB-CD1 4.17Å; L12-L15 HydrophobicContact CD2-CD1 4.04Å; L12-W90 HydrophobicContact CB-CZ3 4.3Å; L12-W90 HydrophobicContact CD1-CE3 4.34Å; L12-W90 HydrophobicContact CD1-CZ3 4.05Å; L12-W90 HydrophobicContact CD2-CE3 3.57Å; L12-W90 HydrophobicContact CD2-CZ3 3.55Å; L12-W90 HydrophobicContact CG-CZ3 4.16Å
13	N	68.7	Low	72.9	Confident	121 Å²	121	76.1 Å²	76.1	65%	0.647	42%	0.42	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.4	-1.8	-168.4	-74.5	-16.1	0	0	0	115.3	S9	S9-N13 PolarHBondContact O-ND2 3.37Å; S9-N13 PolarHBondContact O-OD1 3.46Å
14	S	78.4	Confident	75	Confident	106 Å²	106	74.5 Å²	74.5	74%	0.741	40%	0.404	S	S	*	.	T	Hydrogen-bonded Turn	trans	-127.8	22.9	-175.9	60.5	0	0	0	0	114.4	L12	L12-S14 PolarHBondContact O-N 3.15Å; L12-S14 VanDerWaalsContact O-N 3.15Å
15	L	83.4	Confident	77.2	Confident	35 Å²	35	70 Å²	70	18%	0.183	38%	0.38	C	S	.	.			trans	-92.8	137.2	-174.8	-63.8	163	0	0	0	111.6	L12 E19 I20 Y23 W90	L12-L15 HydrophobicContact CB-CD1 4.17Å; L12-L15 HydrophobicContact CD2-CD1 4.04Å; L15-E19 HydrophobicContact CD2-CG 3.75Å; L15-E19 WeakPolarHBondContact CD2-OE1 3.46Å; L15-E19 WeakPolarHBondContact CD2-OE2 3.12Å; L15-I20 HydrophobicContact CB-CD1 4.47Å; L15-I20 HydrophobicContact CB-CG1 3.95Å; L15-Y23 HydrophobicContact CD2-CD2 4.39Å; L15-Y23 HydrophobicContact CD2-CE2 3.83Å; L15-W90 HydrophobicContact CD1-CE3 4.17Å; L15-W90 HydrophobicContact CD1-CH2 4.27Å; L15-W90 HydrophobicContact CD1-CZ3 3.4Å
16	T	88.6	Confident	79.4	Confident	47 Å²	47	66.3 Å²	66.3	29%	0.288	36%	0.356	S	S	.	.			trans	-72.5	158.1	173	64.8	0	0	0	0	111.4	E18 E19 I20 Y291	T16-E18 PolarHBondContact O-N 3.22Å; T16-E19 PolarHBondContact O-N 3.34Å; T16-E19 VanDerWaalsContact O-N 3.07Å; T16-E19 WeakPolarHBondContact OG1-CB 3.06Å; T16-E19 PolarHBondContact OG1-N 3.21Å; T16-I20 WeakPolarHBondContact O-CG1 3.1Å; T16-I20 PolarHBondContact O-N 3.22Å; T16-Y291 HydrophobicContact CG2-CD1 3.83Å; T16-Y291 HydrophobicContact CG2-CE1 3.57Å; T16-Y291 WeakPolarHBondContact OG1-CE1 3.47Å
17	N	90.7	Very high	81.7	Confident	131 Å²	131	61 Å²	61	70%	0.701	33%	0.328	S	S	*	.	H	α-helix	trans	-55.3	-39.6	177	-69.7	-15.7	0	0	0	112.7	E19 I20 M21	N17-E19 VanDerWaalsContact C-N 3.34Å; N17-I20 PolarHBondContact O-N 3.19Å; N17-M21 PolarHBondContact O-N 3.29Å
18	E	91.1	Very high	83.9	Confident	41 Å²	41	60 Å²	60	19%	0.192	32%	0.319	C	S	.	.	H	α-helix	trans	-65.2	-39.5	178.7	-64.6	80.9	176.7	0	0	111.6	T16 M21 V22 K292 Q295	T16-E18 PolarHBondContact O-N 3.22Å; E18-M21 WeakPolarHBondContact O-CB 3.48Å; E18-M21 PolarHBondContact O-N 2.72Å; E18-V22 WeakPolarHBondContact O-CG2 3.26Å; E18-V22 PolarHBondContact O-N 2.73Å; E18-V22 VanDerWaalsContact O-N 3.1Å; E18-K292 HydrophobicContact CG-CG 4.23Å; E18-K292 WeakPolarHBondContact OE1-CD 3.29Å; E18-K292 WeakPolarHBondContact OE1-CE 3.34Å; E18-K292 WeakPolarHBondContact OE1-CG 3.39Å; E18-K292 IonicContact OE1-NZ 3.1Å; E18-K292 PolarHBondContact OE1-NZ 2.93Å; E18-Q295 HydrophobicContact CB-CB 3.93Å
19	E	90.6	Very high	86.1	Confident	17 Å²	17	60.4 Å²	60.4	8%	0.079	32%	0.321	C	S	.	.	H	α-helix	trans	-72.4	-38.1	178.1	-173.8	172.5	-159.9	0	0	112.4	L15 T16 N17 M21 V22 Y23 Y291 Q295	L15-E19 HydrophobicContact CD2-CG 3.75Å; L15-E19 WeakPolarHBondContact CD2-OE1 3.46Å; L15-E19 WeakPolarHBondContact CD2-OE2 3.12Å; T16-E19 PolarHBondContact O-N 3.34Å; T16-E19 VanDerWaalsContact O-N 3.07Å; T16-E19 WeakPolarHBondContact OG1-CB 3.06Å; T16-E19 PolarHBondContact OG1-N 3.21Å; N17-E19 VanDerWaalsContact C-N 3.34Å; E19-M21 PolarHBondContact O-N 3.2Å; E19-V22 PolarHBondContact O-N 2.71Å; E19-Y23 HydrophobicContact CG-CD2 3.68Å; E19-Y23 HydrophobicContact CG-CE2 3.33Å; E19-Y23 VanDerWaalsContact O-CD2 3.27Å; E19-Y23 WeakPolarHBondContact O-CD2 2.99Å; E19-Y23 PolarHBondContact O-N 2.93Å; E19-Y23 WeakPolarHBondContact OE1-CE2 3.04Å; E19-Y23 PolarHBondContact OE1-OH 3.12Å; E19-Y291 PolarHBondContact OE1-OH 3.29Å; E19-Y291 PolarHBondContact OE2-OH 3.27Å; E19-Q295 HydrophobicContact CB-CG 4.22Å
20	I	92.7	Very high	88.3	Confident	53 Å²	53	57.6 Å²	57.6	27%	0.272	30%	0.301	S	S	.	.	H	α-helix	trans	-57.6	-41.4	170.5	-67.4	168	0	0	0	110.1	L15 T16 N17 Y23 N24 W90	L15-I20 HydrophobicContact CB-CD1 4.47Å; L15-I20 HydrophobicContact CB-CG1 3.95Å; T16-I20 WeakPolarHBondContact O-CG1 3.1Å; T16-I20 PolarHBondContact O-N 3.22Å; N17-I20 PolarHBondContact O-N 3.19Å; I20-Y23 PolarHBondContact O-N 2.68Å; I20-N24 WeakPolarHBondContact CG2-ND2 3.32Å; I20-N24 VanDerWaalsContact O-CB 3.25Å; I20-N24 WeakPolarHBondContact O-CB 3.11Å; I20-N24 VanDerWaalsContact O-CG 3.29Å; I20-N24 PolarHBondContact O-N 3.26Å; I20-N24 PolarHBondContact O-ND2 2.67Å; I20-W90 HydrophobicContact CG1-CH2 4.12Å; I20-W90 HydrophobicContact CG2-CH2 4.22Å; I20-W90 HydrophobicContact CG2-CZ2 4.1Å
21	M	94.4	Very high	89.9	Confident	106 Å²	106	53.9 Å²	53.9	52%	0.522	28%	0.282	S	S	.	.	H	α-helix	trans	-63.4	-43.6	176.7	-170	179.1	179.3	0	0	112.1	N17 E18 E19 F25 L299	N17-M21 PolarHBondContact O-N 3.29Å; E18-M21 WeakPolarHBondContact O-CB 3.48Å; E18-M21 PolarHBondContact O-N 2.72Å; E19-M21 PolarHBondContact O-N 3.2Å; M21-F25 WeakPolarHBondContact O-CB 3.37Å; M21-F25 PolarHBondContact O-N 2.72Å; M21-L299 HydrophobicContact CE-CD1 4.34Å; M21-L299 HydrophobicContact CE-CD2 3.55Å; M21-L299 HydrophobicContact CG-CD1 4.08Å; M21-L299 HydrophobicContact CG-CD2 4.01Å; M21-L299 HydrophobicContact SD-CD2 3.44Å; M21-L299 WeakPolarHBondContact SD-CD2 3.35Å
22	V	95.2	Very high	91.2	Very high	1 Å²	1	56.1 Å²	56.1	1%	0.006	29%	0.291	C	S	.	.	H	α-helix	trans	-60.1	-49.9	175.8	172.5	0	0	0	0	110.9	E18 E19 F25 R26 Q295 K298 L299	E18-V22 WeakPolarHBondContact O-CG2 3.26Å; E18-V22 PolarHBondContact O-N 2.73Å; E18-V22 VanDerWaalsContact O-N 3.1Å; E19-V22 PolarHBondContact O-N 2.71Å; V22-F25 PolarHBondContact O-N 2.94Å; V22-R26 WeakPolarHBondContact O-CB 3.47Å; V22-R26 WeakPolarHBondContact O-CG 3.27Å; V22-R26 PolarHBondContact O-N 3.36Å; V22-Q295 HydrophobicContact CG2-CB 4.38Å; V22-Q295 VanDerWaalsContact CG2-O 3.25Å; V22-Q295 WeakPolarHBondContact CG2-O 3.49Å; V22-K298 HydrophobicContact CG1-CB 4.3Å; V22-K298 HydrophobicContact CG2-CB 4.39Å; V22-L299 HydrophobicContact CG2-CB 3.81Å
23	Y	93.7	Very high	92.3	Very high	55 Å²	55	54.4 Å²	54.4	22%	0.216	28%	0.282	C	S	.	.	H	α-helix	trans	-67.4	-40.2	-178.6	-74.3	-55.7	0	0	0	112.6	L15 E19 I20 F25 R26 A27 R86 W90	L15-Y23 HydrophobicContact CD2-CD2 4.39Å; L15-Y23 HydrophobicContact CD2-CE2 3.83Å; E19-Y23 HydrophobicContact CG-CD2 3.68Å; E19-Y23 HydrophobicContact CG-CE2 3.33Å; E19-Y23 VanDerWaalsContact O-CD2 3.27Å; E19-Y23 WeakPolarHBondContact O-CD2 2.99Å; E19-Y23 PolarHBondContact O-N 2.93Å; E19-Y23 WeakPolarHBondContact OE1-CE2 3.04Å; E19-Y23 PolarHBondContact OE1-OH 3.12Å; I20-Y23 PolarHBondContact O-N 2.68Å; Y23-F25 PolarHBondContact O-N 3.02Å; Y23-R26 PolarHBondContact O-N 2.89Å; Y23-A27 WeakPolarHBondContact O-CB 3.3Å; Y23-A27 PolarHBondContact O-N 2.92Å; Y23-R86 HydrophobicContact CD1-CB 4.43Å; Y23-R86 HydrophobicContact CE1-CB 4.14Å; Y23-W90 HydrophobicContact CD1-CB 4.41Å; Y23-W90 HydrophobicContact CD2-CE3 4.15Å; Y23-W90 HydrophobicContact CG-CB 4.36Å; Y23-W90 HydrophobicContact CG-CD2 4.33Å; Y23-W90 HydrophobicContact CG-CE3 4.15Å; Y23-W90 HydrophobicContact CG-CG 4.44Å
24	N	95.3	Very high	93.7	Very high	60 Å²	60	48.9 Å²	48.9	32%	0.321	25%	0.253	S	S	.	.	H	α-helix	trans	-59.9	-44.9	173.6	-81.7	-31.7	0	0	0	111.9	I20 A27 Y28 W90	I20-N24 WeakPolarHBondContact CG2-ND2 3.32Å; I20-N24 VanDerWaalsContact O-CB 3.25Å; I20-N24 WeakPolarHBondContact O-CB 3.11Å; I20-N24 VanDerWaalsContact O-CG 3.29Å; I20-N24 PolarHBondContact O-N 3.26Å; I20-N24 PolarHBondContact O-ND2 2.67Å; N24-A27 PolarHBondContact O-N 3.34Å; N24-Y28 WeakPolarHBondContact O-CD2 3.43Å; N24-Y28 PolarHBondContact O-N 2.99Å; N24-Y28 VanDerWaalsContact O-N 3.09Å; N24-W90 PolarHBondContact OD1-NE1 2.81Å
25	F	97.1	Very high	94.6	Very high	26 Å²	26	50 Å²	50	11%	0.114	25%	0.25	C	C	.	.	I	π-helix	trans	-60.7	-49.1	177.4	-171.3	-81.6	0	0	0	111	M21 V22 Y23 A27 Y28 I29 S30 L33 L299 I303 F306	M21-F25 WeakPolarHBondContact O-CB 3.37Å; M21-F25 PolarHBondContact O-N 2.72Å; V22-F25 PolarHBondContact O-N 2.94Å; Y23-F25 PolarHBondContact O-N 3.02Å; F25-A27 VanDerWaalsContact C-N 3.33Å; F25-A27 PolarHBondContact O-N 3.36Å; F25-Y28 PolarHBondContact O-N 2.9Å; F25-I29 HydrophobicContact CD1-CB 4.24Å; F25-I29 HydrophobicContact CD2-CB 3.95Å; F25-I29 HydrophobicContact CD2-CG1 4Å; F25-I29 HydrophobicContact CD2-CG2 4.15Å; F25-I29 HydrophobicContact CE1-CB 4.21Å; F25-I29 HydrophobicContact CE1-CG2 4.08Å; F25-I29 HydrophobicContact CE2-CB 3.93Å; F25-I29 HydrophobicContact CE2-CG1 4.25Å; F25-I29 HydrophobicContact CE2-CG2 3.6Å; F25-I29 HydrophobicContact CG-CB 4.11Å; F25-I29 HydrophobicContact CG-CG1 4.4Å; F25-I29 HydrophobicContact CZ-CB 4.06Å; F25-I29 HydrophobicContact CZ-CG2 3.56Å; F25-I29 WeakPolarHBondContact O-CA 3.27Å; F25-I29 WeakPolarHBondContact O-CB 3.27Å; F25-I29 PolarHBondContact O-N 3.36Å; F25-S30 PolarHBondContact O-N 2.86Å; F25-L33 HydrophobicContact CZ-CD1 4.24Å; F25-L299 HydrophobicContact CB-CD1 4Å; F25-L299 HydrophobicContact CD2-CD1 4.37Å; F25-L299 HydrophobicContact CG-CD1 4.21Å; F25-I303 HydrophobicContact CD2-CG1 4.39Å; F25-I303 HydrophobicContact CE2-CG1 3.78Å; F25-I303 HydrophobicContact CZ-CG1 3.94Å; F25-F306 AromaticContact CE2-CE2 3.93Å; F25-F306 HydrophobicContact CE2-CE2 3.93Å; F25-F306 HydrophobicContact CZ-CD2 4.4Å; F25-F306 AromaticContact CZ-CE2 3.79Å; F25-F306 HydrophobicContact CZ-CE2 3.79Å
26	R	96.5	Very high	95.3	Very high	10 Å²	10	51.5 Å²	51.5	4%	0.038	26%	0.257	C	S	.	.	I	π-helix	trans	-65.4	-32.9	-179.7	-73.4	177.9	167.8	178.7	-20	113.8	V22 Y23 P31 D82 S302	V22-R26 WeakPolarHBondContact O-CB 3.47Å; V22-R26 WeakPolarHBondContact O-CG 3.27Å; V22-R26 PolarHBondContact O-N 3.36Å; Y23-R26 PolarHBondContact O-N 2.89Å; R26-P31 WeakPolarHBondContact O-CD 3.45Å; R26-D82 HydrophobicContact CB-CB 4.48Å; R26-D82 HydrophobicContact CG-CB 3.95Å; R26-D82 IonicContact CZ-OD1 3.91Å; R26-D82 IonicContact NE-OD1 2.69Å; R26-D82 PolarHBondContact NE-OD1 3.16Å; R26-D82 IonicContact NH2-OD1 3.95Å; R26-D82 PolarHBondContact NH2-OD1 3.08Å; R26-S302 PolarHBondContact NE-OG 3.39Å
27	A	95.9	Very high	95.8	Very high	4 Å²	4	49.3 Å²	49.3	3%	0.033	24%	0.244	C	C	.	.	I	π-helix	trans	-76.5	-36.8	-179.7	0	0	0	0	0	113.6	Y23 N24 F25 P31 G87 W90 A91	Y23-A27 WeakPolarHBondContact O-CB 3.3Å; Y23-A27 PolarHBondContact O-N 2.92Å; N24-A27 PolarHBondContact O-N 3.34Å; F25-A27 VanDerWaalsContact C-N 3.33Å; F25-A27 PolarHBondContact O-N 3.36Å; A27-P31 VanDerWaalsContact O-CG 3.27Å; A27-P31 WeakPolarHBondContact O-CG 3.39Å; A27-G87 VanDerWaalsContact CB-O 3.3Å; A27-G87 WeakPolarHBondContact CB-O 3.36Å; A27-W90 HydrophobicContact CB-CB 4.33Å; A27-W90 HydrophobicContact CB-CG 4.34Å; A27-A91 HydrophobicContact CB-CB 4.13Å
28	Y	97.1	Very high	96.1	Very high	141 Å²	141	44.9 Å²	44.9	55%	0.553	22%	0.22	S	C	*	.	I	π-helix	trans	-117.9	-37.3	-170.1	-59.5	-64.7	0	0	0	114	N24 F25	N24-Y28 WeakPolarHBondContact O-CD2 3.43Å; N24-Y28 PolarHBondContact O-N 2.99Å; N24-Y28 VanDerWaalsContact O-N 3.09Å; F25-Y28 PolarHBondContact O-N 2.9Å
29	I	97.8	Very high	96.5	Very high	61 Å²	61	45.5 Å²	45.5	31%	0.313	23%	0.227	S	C	.	.	I	π-helix	trans	-88	-48.3	-177	-53.5	-58.9	0	0	0	111.1	F25 L32 L33 F306	F25-I29 HydrophobicContact CD1-CB 4.24Å; F25-I29 HydrophobicContact CD2-CB 3.95Å; F25-I29 HydrophobicContact CD2-CG1 4Å; F25-I29 HydrophobicContact CD2-CG2 4.15Å; F25-I29 HydrophobicContact CE1-CB 4.21Å; F25-I29 HydrophobicContact CE1-CG2 4.08Å; F25-I29 HydrophobicContact CE2-CB 3.93Å; F25-I29 HydrophobicContact CE2-CG1 4.25Å; F25-I29 HydrophobicContact CE2-CG2 3.6Å; F25-I29 HydrophobicContact CG-CB 4.11Å; F25-I29 HydrophobicContact CG-CG1 4.4Å; F25-I29 HydrophobicContact CZ-CB 4.06Å; F25-I29 HydrophobicContact CZ-CG2 3.56Å; F25-I29 WeakPolarHBondContact O-CA 3.27Å; F25-I29 WeakPolarHBondContact O-CB 3.27Å; F25-I29 PolarHBondContact O-N 3.36Å; I29-L32 WeakPolarHBondContact O-CB 3.5Å; I29-L32 PolarHBondContact O-N 2.88Å; I29-L32 VanDerWaalsContact O-N 3.12Å; I29-L33 HydrophobicContact CG2-CD1 3.96Å; I29-L33 HydrophobicContact CG2-CG 4.1Å; I29-L33 WeakPolarHBondContact O-CG 3.36Å; I29-L33 PolarHBondContact O-N 2.85Å; I29-F306 HydrophobicContact CG2-CE2 4.43Å; I29-F306 HydrophobicContact CG2-CZ 4.03Å
30	S	97.5	Very high	96.8	Very high	0 Å²	0	45 Å²	45	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-54.4	-45.7	178.6	-61.6	0	0	0	0	114.2	F25 L32 L33 S34 T78	F25-S30 PolarHBondContact O-N 2.86Å; S30-L32 PolarHBondContact O-N 2.64Å; S30-L33 PolarHBondContact O-N 3.01Å; S30-S34 PolarHBondContact O-N 3.25Å; S30-T78 WeakPolarHBondContact O-CG2 3.3Å
31	P	97.4	Very high	97.1	Very high	27 Å²	27	42.5 Å²	42.5	18%	0.175	21%	0.213	C	C	.	.	H	α-helix	trans	-63.5	-38.9	176	22.5	-32.9	0	0	0	112.7	R26 A27 L33 S34 L35 F83	R26-P31 WeakPolarHBondContact O-CD 3.45Å; A27-P31 VanDerWaalsContact O-CG 3.27Å; A27-P31 WeakPolarHBondContact O-CG 3.39Å; P31-L33 VanDerWaalsContact C-N 3.35Å; P31-L33 PolarHBondContact O-N 2.87Å; P31-S34 WeakPolarHBondContact CA-OG 3.39Å; P31-S34 PolarHBondContact O-N 3.28Å; P31-S34 PolarHBondContact O-OG 3.41Å; P31-L35 VanDerWaalsContact O-CB 3.31Å; P31-L35 WeakPolarHBondContact O-CB 3.45Å; P31-L35 PolarHBondContact O-N 3.1Å; P31-F83 HydrophobicContact CB-CB 4.42Å; P31-F83 HydrophobicContact CB-CD1 4.11Å; P31-F83 HydrophobicContact CB-CD2 3.62Å; P31-F83 HydrophobicContact CB-CE1 4.27Å; P31-F83 HydrophobicContact CB-CE2 3.8Å; P31-F83 HydrophobicContact CB-CG 3.78Å; P31-F83 HydrophobicContact CB-CZ 4.11Å; P31-F83 HydrophobicContact CG-CD2 3.53Å; P31-F83 HydrophobicContact CG-CE2 3.74Å; P31-F83 HydrophobicContact CG-CG 4.15Å
32	L	98	Very high	97.2	Very high	93 Å²	93	40.9 Å²	40.9	49%	0.487	21%	0.206	S	C	.	.	H	α-helix	trans	-61.9	-43.9	175.5	-178.9	65.9	0	0	0	111.3	I29 S30 L35 I36	I29-L32 WeakPolarHBondContact O-CB 3.5Å; I29-L32 PolarHBondContact O-N 2.88Å; I29-L32 VanDerWaalsContact O-N 3.12Å; S30-L32 PolarHBondContact O-N 2.64Å; L32-L35 PolarHBondContact O-N 2.99Å; L32-I36 HydrophobicContact CD1-CD1 3.89Å; L32-I36 HydrophobicContact CD1-CG1 4.47Å; L32-I36 HydrophobicContact CG-CD1 4.05Å; L32-I36 WeakPolarHBondContact O-CG1 3.48Å; L32-I36 PolarHBondContact O-N 3.15Å; L32-I36 VanDerWaalsContact O-N 3.08Å
33	L	98	Very high	97.3	Very high	8 Å²	8	44.8 Å²	44.8	4%	0.042	22%	0.223	C	C	.	.	H	α-helix	trans	-61.9	-44	175.1	-68.4	179.5	0	0	0	111.8	F25 I29 S30 P31 I36 G37 T78 F306 T309	F25-L33 HydrophobicContact CZ-CD1 4.24Å; I29-L33 HydrophobicContact CG2-CD1 3.96Å; I29-L33 HydrophobicContact CG2-CG 4.1Å; I29-L33 WeakPolarHBondContact O-CG 3.36Å; I29-L33 PolarHBondContact O-N 2.85Å; S30-L33 PolarHBondContact O-N 3.01Å; P31-L33 VanDerWaalsContact C-N 3.35Å; P31-L33 PolarHBondContact O-N 2.87Å; L33-I36 PolarHBondContact O-N 3Å; L33-G37 WeakPolarHBondContact O-CA 3.4Å; L33-G37 PolarHBondContact O-N 3.2Å; L33-T78 HydrophobicContact CB-CG2 4.29Å; L33-F306 HydrophobicContact CD1-CD1 4.2Å; L33-F306 HydrophobicContact CD1-CD2 4.27Å; L33-F306 HydrophobicContact CD1-CE1 4.26Å; L33-F306 HydrophobicContact CD1-CE2 4.25Å; L33-F306 HydrophobicContact CD1-CG 4.26Å; L33-F306 HydrophobicContact CD1-CZ 4.27Å; L33-F306 HydrophobicContact CD2-CD1 3.53Å; L33-F306 HydrophobicContact CD2-CE1 3.53Å; L33-F306 HydrophobicContact CD2-CG 4.34Å; L33-F306 HydrophobicContact CD2-CZ 4.25Å; L33-F306 HydrophobicContact CG-CE1 4.41Å; L33-T309 HydrophobicContact CD2-CG2 4.02Å
34	S	97.7	Very high	97.5	Very high	5 Å²	5	42.1 Å²	42.1	4%	0.035	21%	0.213	C	C	.	.	H	α-helix	trans	-64.8	-41.4	176.9	72.3	0	0	0	0	112.5	S30 P31 I36 G37 I38	S30-S34 PolarHBondContact O-N 3.25Å; P31-S34 WeakPolarHBondContact CA-OG 3.39Å; P31-S34 PolarHBondContact O-N 3.28Å; P31-S34 PolarHBondContact O-OG 3.41Å; S34-I36 VanDerWaalsContact C-N 3.32Å; S34-I36 PolarHBondContact O-N 3.24Å; S34-G37 PolarHBondContact O-N 2.87Å; S34-I38 VanDerWaalsContact O-CB 3.3Å; S34-I38 WeakPolarHBondContact O-CB 3.24Å; S34-I38 VanDerWaalsContact O-CG1 3.32Å; S34-I38 WeakPolarHBondContact O-CG1 3.39Å; S34-I38 PolarHBondContact O-N 3.22Å
35	L	97.8	Very high	97.7	Very high	128 Å²	128	40.7 Å²	40.7	67%	0.67	21%	0.205	S	C	*	.	H	α-helix	trans	-65	-35.3	-179.2	-176.3	67.9	0	0	0	112.1	P31 L32 P39	P31-L35 VanDerWaalsContact O-CB 3.31Å; P31-L35 WeakPolarHBondContact O-CB 3.45Å; P31-L35 PolarHBondContact O-N 3.1Å; L32-L35 PolarHBondContact O-N 2.99Å; L35-P39 WeakPolarHBondContact O-CD 3.47Å; L35-P39 VanDerWaalsContact O-CG 3.25Å; L35-P39 WeakPolarHBondContact O-CG 3.29Å
36	I	98.2	Very high	97.7	Very high	68 Å²	68	42.3 Å²	42.3	35%	0.349	21%	0.214	S	C	.	.	H	α-helix	trans	-84.2	-47.4	176.5	-64.8	171	0	0	0	110.4	L32 L33 S34 P39 A40 T309 F313	L32-I36 HydrophobicContact CD1-CD1 3.89Å; L32-I36 HydrophobicContact CD1-CG1 4.47Å; L32-I36 HydrophobicContact CG-CD1 4.05Å; L32-I36 WeakPolarHBondContact O-CG1 3.48Å; L32-I36 PolarHBondContact O-N 3.15Å; L32-I36 VanDerWaalsContact O-N 3.08Å; L33-I36 PolarHBondContact O-N 3Å; S34-I36 VanDerWaalsContact C-N 3.32Å; S34-I36 PolarHBondContact O-N 3.24Å; I36-P39 WeakPolarHBondContact O-CD 3.28Å; I36-A40 WeakPolarHBondContact O-CB 3.5Å; I36-A40 PolarHBondContact O-N 3.12Å; I36-T309 HydrophobicContact CB-CG2 4.32Å; I36-T309 HydrophobicContact CG2-CG2 4.09Å; I36-F313 HydrophobicContact CG2-CE2 3.79Å; I36-F313 HydrophobicContact CG2-CZ 3.83Å
37	G	98.1	Very high	97.7	Very high	0 Å²	0	41.8 Å²	41.8	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-69.5	-39.2	-170.1	0	0	0	0	0	114.1	L33 S34 A40 N41	L33-G37 WeakPolarHBondContact O-CA 3.4Å; L33-G37 PolarHBondContact O-N 3.2Å; S34-G37 PolarHBondContact O-N 2.87Å; G37-A40 PolarHBondContact O-N 3.17Å; G37-N41 WeakPolarHBondContact O-CB 3.48Å; G37-N41 PolarHBondContact O-N 3.34Å; G37-N41 PolarHBondContact O-ND2 3.2Å
38	I	98.5	Very high	97.8	Very high	38 Å²	38	41.6 Å²	41.6	20%	0.195	21%	0.21	C	C	.	.	H	α-helix	trans	-64.1	-55.3	179.7	-69.4	169.6	0	0	0	110.3	S34 A40 N41 I42 L71 L74 I75	S34-I38 VanDerWaalsContact O-CB 3.3Å; S34-I38 WeakPolarHBondContact O-CB 3.24Å; S34-I38 VanDerWaalsContact O-CG1 3.32Å; S34-I38 WeakPolarHBondContact O-CG1 3.39Å; S34-I38 PolarHBondContact O-N 3.22Å; I38-A40 VanDerWaalsContact C-N 3.31Å; I38-A40 PolarHBondContact O-N 3.3Å; I38-N41 PolarHBondContact O-N 3.33Å; I38-I42 HydrophobicContact CG2-CD1 3.99Å; I38-I42 VanDerWaalsContact O-CG1 3.29Å; I38-I42 WeakPolarHBondContact O-CG1 3.4Å; I38-I42 PolarHBondContact O-N 3.5Å; I38-I42 VanDerWaalsContact O-N 3.1Å; I38-L71 HydrophobicContact CB-CD1 4.32Å; I38-L71 HydrophobicContact CG1-CD1 4.35Å; I38-L71 HydrophobicContact CG2-CD1 3.93Å; I38-L74 HydrophobicContact CG1-CB 4.05Å; I38-I75 HydrophobicContact CD1-CG1 3.82Å; I38-I75 HydrophobicContact CG1-CG1 4.12Å
39	P	98.2	Very high	97.7	Very high	55 Å²	55	38 Å²	38	36%	0.357	20%	0.201	S	C	.	.	H	α-helix	trans	-58.9	-40.7	173.9	-24.9	35	0	0	0	113.1	L35 I36 I42 F43	L35-P39 WeakPolarHBondContact O-CD 3.47Å; L35-P39 VanDerWaalsContact O-CG 3.25Å; L35-P39 WeakPolarHBondContact O-CG 3.29Å; I36-P39 WeakPolarHBondContact O-CD 3.28Å; P39-I42 PolarHBondContact O-N 3.42Å; P39-F43 HydrophobicContact CB-CE2 4.42Å; P39-F43 WeakPolarHBondContact O-CD2 3.48Å; P39-F43 PolarHBondContact O-N 3.43Å
40	A	97.9	Very high	97.7	Very high	6 Å²	6	37.9 Å²	37.9	5%	0.05	20%	0.2	C	C	.	.	H	α-helix	trans	-58.1	-49.6	179.2	0	0	0	0	0	112.2	I36 G37 I38 I42 F43 I44 F312	I36-A40 WeakPolarHBondContact O-CB 3.5Å; I36-A40 PolarHBondContact O-N 3.12Å; G37-A40 PolarHBondContact O-N 3.17Å; I38-A40 VanDerWaalsContact C-N 3.31Å; I38-A40 PolarHBondContact O-N 3.3Å; A40-I42 PolarHBondContact O-N 3.08Å; A40-F43 WeakPolarHBondContact O-CB 3.07Å; A40-F43 PolarHBondContact O-N 3.2Å; A40-I44 WeakPolarHBondContact O-CG1 3.31Å; A40-I44 PolarHBondContact O-N 3.27Å; A40-F312 HydrophobicContact CB-CB 3.65Å; A40-F312 HydrophobicContact CB-CG 4.01Å
41	N	98.1	Very high	97.5	Very high	0 Å²	0	38.5 Å²	38.5	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-66.9	-35.1	177.9	-80	-79.4	0	0	0	112.6	G37 I38 F43 I44 I45 L71 L74 H308	G37-N41 WeakPolarHBondContact O-CB 3.48Å; G37-N41 PolarHBondContact O-N 3.34Å; G37-N41 PolarHBondContact O-ND2 3.2Å; I38-N41 PolarHBondContact O-N 3.33Å; N41-F43 VanDerWaalsContact C-N 3.34Å; N41-F43 PolarHBondContact O-N 3.36Å; N41-I44 WeakPolarHBondContact O-CB 3.35Å; N41-I44 PolarHBondContact O-N 3.12Å; N41-I45 VanDerWaalsContact O-CG1 3.32Å; N41-I45 WeakPolarHBondContact O-CG1 3.36Å; N41-I45 PolarHBondContact O-N 3.49Å; N41-L71 HydrophobicContact CB-CB 4.34Å; N41-L71 HydrophobicContact CB-CD1 4.46Å; N41-L74 VanDerWaalsContact ND2-CD1 3.29Å; N41-L74 WeakPolarHBondContact ND2-CD1 3.49Å; N41-H308 PolarHBondContact ND2-O 3.49Å
42	I	98.1	Very high	97.3	Very high	73 Å²	73	38.4 Å²	38.4	37%	0.374	20%	0.201	S	C	.	.	H	α-helix	trans	-61.3	-44	171.8	-67.1	166.1	0	0	0	110.5	I38 P39 A40 I45 I46 L71	I38-I42 HydrophobicContact CG2-CD1 3.99Å; I38-I42 VanDerWaalsContact O-CG1 3.29Å; I38-I42 WeakPolarHBondContact O-CG1 3.4Å; I38-I42 PolarHBondContact O-N 3.5Å; I38-I42 VanDerWaalsContact O-N 3.1Å; P39-I42 PolarHBondContact O-N 3.42Å; A40-I42 PolarHBondContact O-N 3.08Å; I42-I45 PolarHBondContact O-N 3.5Å; I42-I46 HydrophobicContact CG2-CD1 3.8Å; I42-I46 HydrophobicContact CG2-CG1 4.46Å; I42-I46 VanDerWaalsContact O-CG1 3.32Å; I42-I46 WeakPolarHBondContact O-CG1 3.4Å; I42-I46 PolarHBondContact O-N 2.86Å; I42-L71 HydrophobicContact CG1-CD1 4.19Å; I42-L71 HydrophobicContact CG1-CD2 4.25Å
43	F	97.1	Very high	97	Very high	82 Å²	82	42.6 Å²	42.6	36%	0.36	22%	0.215	S	C	.	.	H	α-helix	trans	-63.1	-41.3	175.1	-76.8	-60.3	0	0	0	112.3	P39 A40 N41 I45 I46 I47 F312 F329	P39-F43 HydrophobicContact CB-CE2 4.42Å; P39-F43 WeakPolarHBondContact O-CD2 3.48Å; P39-F43 PolarHBondContact O-N 3.43Å; A40-F43 WeakPolarHBondContact O-CB 3.07Å; A40-F43 PolarHBondContact O-N 3.2Å; N41-F43 VanDerWaalsContact C-N 3.34Å; N41-F43 PolarHBondContact O-N 3.36Å; F43-I45 VanDerWaalsContact C-N 3.33Å; F43-I45 PolarHBondContact O-N 3.26Å; F43-I46 PolarHBondContact O-N 3.44Å; F43-I47 WeakPolarHBondContact O-CB 3.41Å; F43-I47 VanDerWaalsContact O-CG1 3.24Å; F43-I47 WeakPolarHBondContact O-CG1 3.46Å; F43-I47 PolarHBondContact O-N 2.97Å; F43-F312 HydrophobicContact CB-CD2 4.21Å; F43-F312 HydrophobicContact CB-CE2 3.9Å; F43-F329 HydrophobicContact CE1-CE1 4.29Å
44	I	97.8	Very high	96.6	Very high	0 Å²	0	48.8 Å²	48.8	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-54.5	-51.8	173.8	-66.7	171.4	0	0	0	110	A40 N41 I46 I47 F48 A67 D311 F312 Y315 F322	A40-I44 WeakPolarHBondContact O-CG1 3.31Å; A40-I44 PolarHBondContact O-N 3.27Å; N41-I44 WeakPolarHBondContact O-CB 3.35Å; N41-I44 PolarHBondContact O-N 3.12Å; I44-I46 PolarHBondContact O-N 3.37Å; I44-I47 PolarHBondContact O-N 3.47Å; I44-F48 HydrophobicContact CG2-CD2 3.53Å; I44-F48 HydrophobicContact CG2-CE2 3.78Å; I44-F48 WeakPolarHBondContact O-CB 3.45Å; I44-F48 WeakPolarHBondContact O-CD2 3.22Å; I44-F48 PolarHBondContact O-N 2.86Å; I44-A67 HydrophobicContact CB-CB 4.15Å; I44-A67 HydrophobicContact CG2-CB 3.67Å; I44-D311 HydrophobicContact CD1-CB 3.93Å; I44-F312 HydrophobicContact CD1-CB 3.87Å; I44-F312 HydrophobicContact CG1-CB 4Å; I44-F312 HydrophobicContact CG1-CD2 3.99Å; I44-Y315 HydrophobicContact CD1-CD2 3.86Å; I44-Y315 HydrophobicContact CD1-CE2 4.01Å; I44-Y315 HydrophobicContact CG1-CD2 4.08Å; I44-Y315 HydrophobicContact CG2-CD2 4.26Å; I44-Y315 HydrophobicContact CG2-CE2 4.09Å; I44-F322 HydrophobicContact CG1-CZ 4.49Å
45	I	98.2	Very high	96	Very high	30 Å²	30	54.8 Å²	54.8	15%	0.154	27%	0.271	C	S	.	.	H	α-helix	trans	-58.7	-47.3	179.8	-66.6	165	0	0	0	110.7	N41 I42 F43 N49 A67 I68 L71	N41-I45 VanDerWaalsContact O-CG1 3.32Å; N41-I45 WeakPolarHBondContact O-CG1 3.36Å; N41-I45 PolarHBondContact O-N 3.49Å; I42-I45 PolarHBondContact O-N 3.5Å; F43-I45 VanDerWaalsContact C-N 3.33Å; F43-I45 PolarHBondContact O-N 3.26Å; I45-N49 VanDerWaalsContact CG2-ND2 3.33Å; I45-N49 WeakPolarHBondContact CG2-ND2 3.45Å; I45-N49 WeakPolarHBondContact O-CB 3.39Å; I45-N49 VanDerWaalsContact O-CG 3.25Å; I45-N49 PolarHBondContact O-N 2.83Å; I45-N49 PolarHBondContact O-ND2 3.49Å; I45-A67 HydrophobicContact CD1-CB 4.27Å; I45-A67 HydrophobicContact CG1-CB 3.71Å; I45-I68 HydrophobicContact CD1-CG1 3.8Å; I45-I68 HydrophobicContact CG1-CG1 4.31Å; I45-L71 HydrophobicContact CD1-CD2 4.3Å
46	I	97.5	Very high	95.4	Very high	59 Å²	59	52.3 Å²	52.3	30%	0.303	27%	0.265	S	S	.	.	H	α-helix	trans	-62.3	-50.8	179.7	-68	167.5	0	0	0	110.9	I42 F43 I44 N49 L50 F329	I42-I46 HydrophobicContact CG2-CD1 3.8Å; I42-I46 HydrophobicContact CG2-CG1 4.46Å; I42-I46 VanDerWaalsContact O-CG1 3.32Å; I42-I46 WeakPolarHBondContact O-CG1 3.4Å; I42-I46 PolarHBondContact O-N 2.86Å; F43-I46 PolarHBondContact O-N 3.44Å; I44-I46 PolarHBondContact O-N 3.37Å; I46-N49 PolarHBondContact O-N 3.27Å; I46-L50 HydrophobicContact CG2-CD1 4.23Å; I46-L50 WeakPolarHBondContact O-CG 3.21Å; I46-L50 PolarHBondContact O-N 3Å; I46-F329 HydrophobicContact CG2-CE1 4.35Å; I46-F329 HydrophobicContact CG2-CE2 4.08Å; I46-F329 HydrophobicContact CG2-CZ 3.91Å
47	I	97.3	Very high	94.8	Very high	0 Å²	0	50.4 Å²	50.4	0%	0	26%	0.257	C	S	.	.	H	α-helix	trans	-66	-44.4	-175.2	-65.1	-58	0	0	0	111.1	F43 I44 N49 L50 L51 F322 T325 L326 F329	F43-I47 WeakPolarHBondContact O-CB 3.41Å; F43-I47 VanDerWaalsContact O-CG1 3.24Å; F43-I47 WeakPolarHBondContact O-CG1 3.46Å; F43-I47 PolarHBondContact O-N 2.97Å; I44-I47 PolarHBondContact O-N 3.47Å; I47-N49 VanDerWaalsContact C-N 3.34Å; I47-N49 PolarHBondContact O-N 3.22Å; I47-L50 HydrophobicContact CD1-CD1 4.39Å; I47-L50 WeakPolarHBondContact O-CB 3.37Å; I47-L50 PolarHBondContact O-N 3.35Å; I47-L51 HydrophobicContact CG2-CD1 4.24Å; I47-L51 WeakPolarHBondContact O-CG 3.21Å; I47-L51 PolarHBondContact O-N 3.16Å; I47-F322 HydrophobicContact CB-CD2 4.2Å; I47-F322 HydrophobicContact CB-CE2 3.72Å; I47-F322 HydrophobicContact CB-CZ 4.31Å; I47-F322 HydrophobicContact CG1-CE2 4.33Å; I47-F322 HydrophobicContact CG1-CZ 4.43Å; I47-F322 HydrophobicContact CG2-CD2 3.47Å; I47-F322 VanDerWaalsContact CG2-CD2 3.47Å; I47-F322 HydrophobicContact CG2-CE2 3.53Å; I47-F322 HydrophobicContact CG2-CG 4.18Å; I47-F322 HydrophobicContact CG2-CZ 4.29Å; I47-T325 HydrophobicContact CD1-CG2 4.33Å; I47-T325 HydrophobicContact CG2-CG2 3.97Å; I47-L326 HydrophobicContact CD1-CB 4.26Å; I47-L326 HydrophobicContact CD1-CD1 3.94Å; I47-L326 HydrophobicContact CG1-CB 4.5Å; I47-L326 HydrophobicContact CG1-CD1 3.99Å; I47-F329 HydrophobicContact CD1-CB 3.93Å; I47-F329 HydrophobicContact CD1-CD1 4.19Å; I47-F329 HydrophobicContact CD1-CG 4.12Å
48	F	97.2	Very high	94.5	Very high	0 Å²	0	52.5 Å²	52.5	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-70.1	-30.7	177	-77.6	-65.7	0	0	0	112.8	I44 L50 L51 E52 F59 N60 A63 I64 Y315 L319 F322	I44-F48 HydrophobicContact CG2-CD2 3.53Å; I44-F48 HydrophobicContact CG2-CE2 3.78Å; I44-F48 WeakPolarHBondContact O-CB 3.45Å; I44-F48 WeakPolarHBondContact O-CD2 3.22Å; I44-F48 PolarHBondContact O-N 2.86Å; F48-L50 VanDerWaalsContact C-N 3.34Å; F48-L51 HydrophobicContact CD1-CD1 3.82Å; F48-L51 HydrophobicContact CE1-CD1 4.05Å; F48-L51 PolarHBondContact O-N 3.32Å; F48-E52 VanDerWaalsContact O-CB 3.24Å; F48-E52 WeakPolarHBondContact O-CB 3.46Å; F48-E52 PolarHBondContact O-N 3.46Å; F48-F59 HydrophobicContact CE1-CD1 4.07Å; F48-F59 AromaticContact CE1-CE1 3.77Å; F48-F59 HydrophobicContact CE1-CE1 3.77Å; F48-F59 AromaticContact CZ-CE1 3.86Å; F48-F59 HydrophobicContact CZ-CE1 3.86Å; F48-N60 HydrophobicContact CB-CB 4.47Å; F48-N60 HydrophobicContact CD1-CB 3.97Å; F48-N60 WeakPolarHBondContact CD1-OD1 3.44Å; F48-A63 HydrophobicContact CD1-CB 4.43Å; F48-A63 HydrophobicContact CD2-CB 3.77Å; F48-A63 HydrophobicContact CE1-CB 4.39Å; F48-A63 HydrophobicContact CE2-CB 3.72Å; F48-A63 HydrophobicContact CG-CB 4.14Å; F48-A63 HydrophobicContact CZ-CB 4.04Å; F48-I64 HydrophobicContact CB-CD1 3.96Å; F48-I64 HydrophobicContact CB-CG1 3.52Å; F48-Y315 AromaticContact CE2-CD1 3.95Å; F48-Y315 HydrophobicContact CE2-CD1 3.95Å; F48-Y315 HydrophobicContact CE2-CD2 4Å; F48-Y315 HydrophobicContact CE2-CE1 4.07Å; F48-Y315 HydrophobicContact CE2-CE2 4.13Å; F48-Y315 AromaticContact CE2-CG 3.94Å; F48-Y315 HydrophobicContact CE2-CG 3.94Å; F48-Y315 AromaticContact CZ-CD1 3.7Å; F48-Y315 HydrophobicContact CZ-CD1 3.7Å; F48-Y315 AromaticContact CZ-CE1 3.92Å; F48-Y315 HydrophobicContact CZ-CE1 3.92Å; F48-Y315 HydrophobicContact CZ-CG 4.08Å; F48-L319 HydrophobicContact CE1-CD2 3.93Å; F48-L319 HydrophobicContact CZ-CD2 3.85Å; F48-F322 HydrophobicContact CD2-CD2 4.39Å; F48-F322 HydrophobicContact CD2-CE2 4.2Å; F48-F322 HydrophobicContact CE1-CD2 4.38Å; F48-F322 AromaticContact CE2-CD2 3.82Å; F48-F322 HydrophobicContact CE2-CD2 3.82Å; F48-F322 AromaticContact CE2-CE2 3.83Å; F48-F322 HydrophobicContact CE2-CE2 3.83Å; F48-F322 AromaticContact CZ-CD2 3.81Å; F48-F322 HydrophobicContact CZ-CD2 3.81Å; F48-F322 HydrophobicContact CZ-CE2 4.3Å
49	N	96.4	Very high	94.2	Very high	66 Å²	66	50.7 Å²	50.7	35%	0.353	26%	0.256	S	S	.	.	H	α-helix	trans	-64.4	-38.1	169.8	-83.8	-48.9	0	0	0	112.2	I45 I46 I47 E52 K53	I45-N49 VanDerWaalsContact CG2-ND2 3.33Å; I45-N49 WeakPolarHBondContact CG2-ND2 3.45Å; I45-N49 WeakPolarHBondContact O-CB 3.39Å; I45-N49 VanDerWaalsContact O-CG 3.25Å; I45-N49 PolarHBondContact O-N 2.83Å; I45-N49 PolarHBondContact O-ND2 3.49Å; I46-N49 PolarHBondContact O-N 3.27Å; I47-N49 VanDerWaalsContact C-N 3.34Å; I47-N49 PolarHBondContact O-N 3.22Å; N49-E52 PolarHBondContact O-N 3.47Å; N49-K53 WeakPolarHBondContact O-CG 3.23Å; N49-K53 PolarHBondContact O-N 2.71Å; N49-K53 VanDerWaalsContact O-N 3.08Å
50	L	95.8	Very high	94	Very high	58 Å²	58	48.6 Å²	48.6	30%	0.304	24%	0.241	S	C	.	.	H	α-helix	trans	-65.2	-41.8	173.6	-69.1	173.5	0	0	0	111.5	I46 I47 F48 K53 Q54 T325 F329	I46-L50 HydrophobicContact CG2-CD1 4.23Å; I46-L50 WeakPolarHBondContact O-CG 3.21Å; I46-L50 PolarHBondContact O-N 3Å; I47-L50 HydrophobicContact CD1-CD1 4.39Å; I47-L50 WeakPolarHBondContact O-CB 3.37Å; I47-L50 PolarHBondContact O-N 3.35Å; F48-L50 VanDerWaalsContact C-N 3.34Å; L50-K53 PolarHBondContact O-N 3.49Å; L50-Q54 WeakPolarHBondContact O-CG 3.4Å; L50-Q54 PolarHBondContact O-N 3.5Å; L50-T325 HydrophobicContact CB-CG2 4.31Å; L50-F329 HydrophobicContact CD1-CD2 3.74Å; L50-F329 HydrophobicContact CD1-CE2 4.31Å; L50-F329 HydrophobicContact CD1-CG 4.35Å
51	L	94	Very high	93.8	Very high	13 Å²	13	49 Å²	49	7%	0.068	24%	0.242	C	C	.	.	H	α-helix	trans	-65	-41.7	175.3	-71.4	174	0	0	0	111.9	I47 F48 K53 Q54 Q55 I321 T325	I47-L51 HydrophobicContact CG2-CD1 4.24Å; I47-L51 WeakPolarHBondContact O-CG 3.21Å; I47-L51 PolarHBondContact O-N 3.16Å; F48-L51 HydrophobicContact CD1-CD1 3.82Å; F48-L51 HydrophobicContact CE1-CD1 4.05Å; F48-L51 PolarHBondContact O-N 3.32Å; L51-K53 VanDerWaalsContact C-N 3.31Å; L51-K53 PolarHBondContact O-N 2.89Å; L51-Q54 PolarHBondContact O-N 3.06Å; L51-Q54 VanDerWaalsContact O-N 3.12Å; L51-Q55 CarbonylContact O-C 3Å; L51-Q55 PolarHBondContact O-N 3.16Å; L51-I321 HydrophobicContact CD1-CG2 4.16Å; L51-I321 HydrophobicContact CD2-CG2 3.58Å; L51-T325 HydrophobicContact CD2-CG2 4.18Å; L51-T325 VanDerWaalsContact CD2-OG1 3.23Å; L51-T325 WeakPolarHBondContact CD2-OG1 3.2Å; L51-T325 HydrophobicContact CG-CG2 4.24Å
52	E	92.7	Very high	93.7	Very high	24 Å²	24	49.1 Å²	49.1	11%	0.112	24%	0.243	C	C	.	.	H	α-helix	trans	-65	-35	179.5	-173.9	65.3	-172.8	0	0	112.3	F48 N49 Q54 Q55 S56 C57 N60 I64	F48-E52 VanDerWaalsContact O-CB 3.24Å; F48-E52 WeakPolarHBondContact O-CB 3.46Å; F48-E52 PolarHBondContact O-N 3.46Å; N49-E52 PolarHBondContact O-N 3.47Å; E52-Q54 VanDerWaalsContact C-N 3.33Å; E52-Q55 CarbonylContact O-C 3.51Å; E52-S56 PolarHBondContact O-N 3.03Å; E52-S56 PolarHBondContact O-OG 3.14Å; E52-S56 WeakPolarHBondContact OE1-CA 3.23Å; E52-S56 WeakPolarHBondContact OE1-CB 3.47Å; E52-S56 WeakPolarHBondContact OE2-CA 3.4Å; E52-C57 PolarHBondContact OE2-N 3.05Å; E52-N60 HydrophobicContact CB-CB 4.47Å; E52-N60 WeakPolarHBondContact OE2-CB 3.43Å; E52-I64 HydrophobicContact CB-CD1 4.48Å
53	K	92.1	Very high	93.6	Very high	181 Å²	181	45.7 Å²	45.7	79%	0.787	23%	0.225	S	C	*	.	H	α-helix	trans	-67	-32.7	172.4	-76.2	-179.4	179.8	-173.6	0	112.9	N49 L50 L51	N49-K53 WeakPolarHBondContact O-CG 3.23Å; N49-K53 PolarHBondContact O-N 2.71Å; N49-K53 VanDerWaalsContact O-N 3.08Å; L50-K53 PolarHBondContact O-N 3.49Å; L51-K53 VanDerWaalsContact C-N 3.31Å; L51-K53 PolarHBondContact O-N 2.89Å
54	Q	88.8	Confident	93.6	Very high	138 Å²	138	42.3 Å²	42.3	65%	0.645	21%	0.211	S	C	*	.	H	α-helix	trans	-80	-45.9	178	-70.8	175.9	-2.7	0	0	111.4	L50 L51 E52	L50-Q54 WeakPolarHBondContact O-CG 3.4Å; L50-Q54 PolarHBondContact O-N 3.5Å; L51-Q54 PolarHBondContact O-N 3.06Å; L51-Q54 VanDerWaalsContact O-N 3.12Å; E52-Q54 VanDerWaalsContact C-N 3.33Å
55	Q	85.4	Confident	93.6	Very high	132 Å²	132	46.6 Å²	46.6	62%	0.617	23%	0.227	S	C	*	.	S	Bend	trans	-148.2	107.5	-178.9	-67.6	-174.7	-16.3	0	0	109.3	L51 E52 C57 N60	L51-Q55 CarbonylContact O-C 3Å; L51-Q55 PolarHBondContact O-N 3.16Å; E52-Q55 CarbonylContact O-C 3.51Å; Q55-C57 PolarHBondContact O-N 3.13Å; Q55-N60 PolarHBondContact O-ND2 3.35Å
56	S	85.4	Confident	93.5	Very high	76 Å²	76	45.2 Å²	45.2	53%	0.531	22%	0.22	S	C	.	.			trans	-67.6	121.2	179.9	-54.2	0	0	0	0	111.1	E52	E52-S56 PolarHBondContact O-N 3.03Å; E52-S56 PolarHBondContact O-OG 3.14Å; E52-S56 WeakPolarHBondContact OE1-CA 3.23Å; E52-S56 WeakPolarHBondContact OE1-CB 3.47Å; E52-S56 WeakPolarHBondContact OE2-CA 3.4Å
57	C	87.1	Confident	93.6	Very high	27 Å²	27	42.5 Å²	42.5	18%	0.182	21%	0.207	C	C	.	.			trans	-140.1	136.4	-174.5	-169.8	0	0	0	0	111	E52 Q55 F59 N60 L61	E52-C57 PolarHBondContact OE2-N 3.05Å; Q55-C57 PolarHBondContact O-N 3.13Å; C57-F59 PolarHBondContact O-N 2.72Å; C57-F59 VanDerWaalsContact O-N 3.16Å; C57-N60 PolarHBondContact O-N 3.39Å; C57-L61 PolarHBondContact O-N 3.15Å; C57-L61 VanDerWaalsContact O-N 3.14Å
58	R	90.7	Very high	93.6	Very high	44 Å²	44	45 Å²	45	17%	0.166	22%	0.219	C	C	.	.	H	α-helix	trans	-53.4	-37.7	176.1	-65.9	-176.3	-75.3	159.8	19.4	113.1	L61 Y62 D132 S136 L149 A152	R58-L61 WeakPolarHBondContact O-CB 3.22Å; R58-L61 PolarHBondContact O-N 3.22Å; R58-Y62 HydrophobicContact CB-CE2 4.13Å; R58-Y62 WeakPolarHBondContact O-CD2 3.44Å; R58-Y62 PolarHBondContact O-N 3.3Å; R58-D132 IonicContact CZ-OD1 3.88Å; R58-D132 IonicContact CZ-OD2 3.12Å; R58-D132 IonicContact NE-OD1 3.79Å; R58-D132 IonicContact NH1-OD1 3.22Å; R58-D132 PolarHBondContact NH1-OD1 2.85Å; R58-D132 IonicContact NH2-OD1 3.92Å; R58-S136 PolarHBondContact NH2-OG 3.25Å; R58-L149 HydrophobicContact CG-CD1 4.17Å; R58-A152 HydrophobicContact CG-CB 4.04Å
59	F	91.7	Very high	93.6	Very high	1 Å²	1	45 Å²	45	0%	0.004	22%	0.219	C	C	.	.	H	α-helix	trans	-58.7	-48.5	177.4	-179	-78.7	0	0	0	111.5	F48 C57 L61 Y62 A63 F129 K249 Y315 L319	F48-F59 HydrophobicContact CE1-CD1 4.07Å; F48-F59 AromaticContact CE1-CE1 3.77Å; F48-F59 HydrophobicContact CE1-CE1 3.77Å; F48-F59 AromaticContact CZ-CE1 3.86Å; F48-F59 HydrophobicContact CZ-CE1 3.86Å; C57-F59 PolarHBondContact O-N 2.72Å; C57-F59 VanDerWaalsContact O-N 3.16Å; F59-L61 VanDerWaalsContact C-N 3.3Å; F59-L61 PolarHBondContact O-N 3.3Å; F59-Y62 PolarHBondContact O-N 3.23Å; F59-A63 WeakPolarHBondContact O-CB 3.21Å; F59-A63 PolarHBondContact O-N 2.77Å; F59-F129 AromaticContact CD2-CE2 3.69Å; F59-F129 HydrophobicContact CD2-CE2 3.69Å; F59-F129 AromaticContact CD2-CZ 3.32Å; F59-F129 HydrophobicContact CD2-CZ 3.32Å; F59-F129 HydrophobicContact CE2-CE1 4.37Å; F59-F129 HydrophobicContact CE2-CE2 4.16Å; F59-F129 AromaticContact CE2-CZ 3.43Å; F59-F129 HydrophobicContact CE2-CZ 3.43Å; F59-F129 VanDerWaalsContact CE2-CZ 3.43Å; F59-F129 HydrophobicContact CG-CE2 4.37Å; F59-F129 AromaticContact CG-CZ 3.94Å; F59-F129 HydrophobicContact CG-CZ 3.94Å; F59-F129 HydrophobicContact CZ-CZ 4.15Å; F59-K249 HydrophobicContact CB-CD 4.42Å; F59-K249 HydrophobicContact CD2-CB 3.77Å; F59-K249 HydrophobicContact CD2-CD 4.08Å; F59-K249 HydrophobicContact CD2-CG 3.9Å; F59-K249 HydrophobicContact CE2-CB 3.65Å; F59-K249 HydrophobicContact CE2-CG 3.93Å; F59-K249 HydrophobicContact CG-CD 4.13Å; F59-K249 HydrophobicContact CG-CG 4.25Å; F59-K249 HydrophobicContact CZ-CB 4.38Å; F59-K249 HydrophobicContact CZ-CG 4.28Å; F59-Y315 HydrophobicContact CE1-CE1 4.18Å; F59-Y315 HydrophobicContact CZ-CD1 4.45Å; F59-Y315 AromaticContact CZ-CE1 3.99Å; F59-Y315 HydrophobicContact CZ-CE1 3.99Å; F59-L319 HydrophobicContact CE1-CD2 3.72Å; F59-L319 HydrophobicContact CZ-CD2 4.12Å
60	N	94	Very high	93.7	Very high	11 Å²	11	42.6 Å²	42.6	6%	0.059	21%	0.206	C	C	.	.	H	α-helix	trans	-64.5	-40.8	-179.1	-59.8	-14.1	0	0	0	110.2	F48 E52 Q55 C57 A63 I64	F48-N60 HydrophobicContact CB-CB 4.47Å; F48-N60 HydrophobicContact CD1-CB 3.97Å; F48-N60 WeakPolarHBondContact CD1-OD1 3.44Å; E52-N60 HydrophobicContact CB-CB 4.47Å; E52-N60 WeakPolarHBondContact OE2-CB 3.43Å; Q55-N60 PolarHBondContact O-ND2 3.35Å; C57-N60 PolarHBondContact O-N 3.39Å; N60-A63 PolarHBondContact O-N 3.22Å; N60-I64 WeakPolarHBondContact O-CD1 3.25Å; N60-I64 VanDerWaalsContact O-CG1 3.23Å; N60-I64 WeakPolarHBondContact O-CG1 3.26Å; N60-I64 PolarHBondContact O-N 2.88Å
61	L	94.7	Very high	93.8	Very high	13 Å²	13	41.4 Å²	41.4	7%	0.068	20%	0.2	C	C	.	.	H	α-helix	trans	-59.6	-51.1	177.5	-172.3	70.1	0	0	0	111.8	C57 R58 F59 A63 I64 W65 L149 A152 K153 I156	C57-L61 PolarHBondContact O-N 3.15Å; C57-L61 VanDerWaalsContact O-N 3.14Å; R58-L61 WeakPolarHBondContact O-CB 3.22Å; R58-L61 PolarHBondContact O-N 3.22Å; F59-L61 VanDerWaalsContact C-N 3.3Å; F59-L61 PolarHBondContact O-N 3.3Å; L61-A63 VanDerWaalsContact C-N 3.33Å; L61-A63 PolarHBondContact O-N 3.32Å; L61-I64 PolarHBondContact O-N 2.92Å; L61-W65 PolarHBondContact O-N 2.77Å; L61-W65 VanDerWaalsContact O-N 3.16Å; L61-L149 HydrophobicContact CD2-CD1 4.33Å; L61-A152 HydrophobicContact CD2-CB 4.13Å; L61-K153 HydrophobicContact CD1-CG 4.31Å; L61-K153 HydrophobicContact CD2-CB 4.4Å; L61-K153 HydrophobicContact CD2-CG 3.49Å; L61-K153 VanDerWaalsContact CD2-CG 3.49Å; L61-I156 HydrophobicContact CD2-CD1 3.63Å; L61-I156 HydrophobicContact CG-CD1 3.59Å
62	Y	95.7	Very high	94	Very high	4 Å²	4	43.6 Å²	43.6	2%	0.016	21%	0.211	C	C	.	.	H	α-helix	trans	-60.2	-42.6	177	-65.1	-52.8	0	0	0	112	R58 F59 I64 W65 M66 I125 L128 F129 D132 I156	R58-Y62 HydrophobicContact CB-CE2 4.13Å; R58-Y62 WeakPolarHBondContact O-CD2 3.44Å; R58-Y62 PolarHBondContact O-N 3.3Å; F59-Y62 PolarHBondContact O-N 3.23Å; Y62-I64 PolarHBondContact O-N 3.05Å; Y62-W65 PolarHBondContact O-N 3.12Å; Y62-M66 WeakPolarHBondContact O-CB 3.49Å; Y62-M66 PolarHBondContact O-N 3.07Å; Y62-I125 HydrophobicContact CD1-CG2 4.34Å; Y62-L128 HydrophobicContact CE1-CD2 3.6Å; Y62-L128 HydrophobicContact CE1-CG 3.97Å; Y62-F129 HydrophobicContact CD2-CB 4.41Å; Y62-F129 AromaticContact CD2-CD2 3.68Å; Y62-F129 HydrophobicContact CD2-CD2 3.68Å; Y62-F129 HydrophobicContact CD2-CE2 4.06Å; Y62-F129 HydrophobicContact CD2-CG 4.07Å; Y62-F129 HydrophobicContact CE2-CD2 4.37Å; Y62-F129 HydrophobicContact CG-CB 4.39Å; Y62-F129 HydrophobicContact CG-CD2 4.29Å; Y62-F129 HydrophobicContact CG-CG 4.24Å; Y62-D132 HydrophobicContact CE2-CB 3.91Å; Y62-I156 HydrophobicContact CD1-CD1 3.6Å; Y62-I156 HydrophobicContact CD1-CG1 3.9Å; Y62-I156 HydrophobicContact CE1-CD1 3.75Å; Y62-I156 HydrophobicContact CE1-CG1 3.79Å
63	A	96.2	Very high	94.2	Very high	0 Å²	0	42.9 Å²	42.9	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-62.2	-40.8	178.7	0	0	0	0	0	112.7	F48 F59 N60 L61 A67 Y315	F48-A63 HydrophobicContact CD1-CB 4.43Å; F48-A63 HydrophobicContact CD2-CB 3.77Å; F48-A63 HydrophobicContact CE1-CB 4.39Å; F48-A63 HydrophobicContact CE2-CB 3.72Å; F48-A63 HydrophobicContact CG-CB 4.14Å; F48-A63 HydrophobicContact CZ-CB 4.04Å; F59-A63 WeakPolarHBondContact O-CB 3.21Å; F59-A63 PolarHBondContact O-N 2.77Å; N60-A63 PolarHBondContact O-N 3.22Å; L61-A63 VanDerWaalsContact C-N 3.33Å; L61-A63 PolarHBondContact O-N 3.32Å; A63-A67 VanDerWaalsContact O-CB 3.27Å; A63-A67 WeakPolarHBondContact O-CB 3.35Å; A63-A67 PolarHBondContact O-N 3.31Å; A63-Y315 HydrophobicContact CB-CE1 4.38Å
64	I	97.3	Very high	94.5	Very high	12 Å²	12	34.3 Å²	34.3	6%	0.062	17%	0.17	C	C	.	.	H	α-helix	trans	-63.1	-51.5	177	-67.9	159.7	0	0	0	110.6	F48 E52 N60 L61 Y62 M66 A67 I68	F48-I64 HydrophobicContact CB-CD1 3.96Å; F48-I64 HydrophobicContact CB-CG1 3.52Å; E52-I64 HydrophobicContact CB-CD1 4.48Å; N60-I64 WeakPolarHBondContact O-CD1 3.25Å; N60-I64 VanDerWaalsContact O-CG1 3.23Å; N60-I64 WeakPolarHBondContact O-CG1 3.26Å; N60-I64 PolarHBondContact O-N 2.88Å; L61-I64 PolarHBondContact O-N 2.92Å; Y62-I64 PolarHBondContact O-N 3.05Å; I64-M66 VanDerWaalsContact C-N 3.34Å; I64-M66 PolarHBondContact O-N 3.45Å; I64-A67 PolarHBondContact O-N 3.45Å; I64-I68 HydrophobicContact CG2-CD1 4.12Å; I64-I68 WeakPolarHBondContact O-CG1 3.43Å; I64-I68 PolarHBondContact O-N 2.86Å
65	W	97.7	Very high	94.9	Very high	89 Å²	89	30.8 Å²	30.8	34%	0.337	16%	0.155	S	C	.	.	H	α-helix	trans	-69.8	-31.5	-176.3	-74.4	105.3	0	0	0	113.2	L61 Y62 I68 A69 I125 I156 Y160	L61-W65 PolarHBondContact O-N 2.77Å; L61-W65 VanDerWaalsContact O-N 3.16Å; Y62-W65 PolarHBondContact O-N 3.12Å; W65-I68 HydrophobicContact CD2-CD1 4.49Å; W65-I68 HydrophobicContact CE3-CD1 4.04Å; W65-I68 HydrophobicContact CZ3-CD1 4.4Å; W65-A69 PolarHBondContact O-N 3.48Å; W65-I125 HydrophobicContact CB-CD1 3.95Å; W65-I156 HydrophobicContact CB-CG2 4Å; W65-I156 HydrophobicContact CD2-CG2 3.82Å; W65-I156 HydrophobicContact CE3-CG2 4.45Å; W65-I156 HydrophobicContact CG-CD1 4.37Å; W65-I156 HydrophobicContact CG-CG2 3.6Å; W65-Y160 HydrophobicContact CB-CE2 4.43Å; W65-Y160 HydrophobicContact CD2-CE2 4.23Å; W65-Y160 HydrophobicContact CE3-CD2 4.36Å; W65-Y160 HydrophobicContact CE3-CE1 4.34Å; W65-Y160 AromaticContact CE3-CE2 3.52Å; W65-Y160 HydrophobicContact CE3-CE2 3.52Å; W65-Y160 AromaticContact CE3-CZ 3.54Å; W65-Y160 HydrophobicContact CZ3-CE1 4.32Å; W65-Y160 HydrophobicContact CZ3-CE2 4.09Å; W65-Y160 AromaticContact CZ3-CZ 3.95Å; W65-Y160 PolarHBondContact O-OH 3.35Å
66	M	97	Very high	95.4	Very high	2 Å²	2	25.1 Å²	25.1	1%	0.01	13%	0.13	C	C	.	.	H	α-helix	trans	-66.2	-45.1	170.8	-173.4	-179.8	-64.9	0	0	111.2	Y62 I64 I68 A69 H70 I125 L126 F129	Y62-M66 WeakPolarHBondContact O-CB 3.49Å; Y62-M66 PolarHBondContact O-N 3.07Å; I64-M66 VanDerWaalsContact C-N 3.34Å; I64-M66 PolarHBondContact O-N 3.45Å; M66-I68 VanDerWaalsContact C-N 3.29Å; M66-I68 PolarHBondContact O-N 3.45Å; M66-A69 PolarHBondContact O-N 3.41Å; M66-A69 VanDerWaalsContact O-N 3.14Å; M66-H70 PolarHBondContact O-N 3.47Å; M66-I125 HydrophobicContact CB-CG2 4.13Å; M66-I125 HydrophobicContact CE-CG2 3.86Å; M66-L126 HydrophobicContact CE-CB 3.78Å; M66-L126 HydrophobicContact CE-CD1 3.8Å; M66-L126 HydrophobicContact CE-CG 4.4Å; M66-L126 HydrophobicContact SD-CD1 4.47Å; M66-F129 HydrophobicContact CE-CD1 4.02Å
67	A	97.9	Very high	95.9	Very high	2 Å²	2	22.2 Å²	22.2	2%	0.017	11%	0.108	C	C	.	.	H	α-helix	trans	-63.5	-32.7	177.4	0	0	0	0	0	113	I44 I45 A63 I64 L71	I44-A67 HydrophobicContact CB-CB 4.15Å; I44-A67 HydrophobicContact CG2-CB 3.67Å; I45-A67 HydrophobicContact CD1-CB 4.27Å; I45-A67 HydrophobicContact CG1-CB 3.71Å; A63-A67 VanDerWaalsContact O-CB 3.27Å; A63-A67 WeakPolarHBondContact O-CB 3.35Å; A63-A67 PolarHBondContact O-N 3.31Å; I64-A67 PolarHBondContact O-N 3.45Å; A67-L71 VanDerWaalsContact O-CB 3.26Å; A67-L71 WeakPolarHBondContact O-CB 3.44Å; A67-L71 PolarHBondContact O-N 3.03Å
68	I	98.2	Very high	96.4	Very high	52 Å²	52	20.9 Å²	20.9	27%	0.267	10%	0.099	S	C	.	.	H	α-helix	trans	-63.5	-46.7	172.2	-69	167.4	0	0	0	110.6	I45 I64 W65 M66 L71 I72	I45-I68 HydrophobicContact CD1-CG1 3.8Å; I45-I68 HydrophobicContact CG1-CG1 4.31Å; I64-I68 HydrophobicContact CG2-CD1 4.12Å; I64-I68 WeakPolarHBondContact O-CG1 3.43Å; I64-I68 PolarHBondContact O-N 2.86Å; W65-I68 HydrophobicContact CD2-CD1 4.49Å; W65-I68 HydrophobicContact CE3-CD1 4.04Å; W65-I68 HydrophobicContact CZ3-CD1 4.4Å; M66-I68 VanDerWaalsContact C-N 3.29Å; M66-I68 PolarHBondContact O-N 3.45Å; I68-L71 PolarHBondContact O-N 3.41Å; I68-I72 HydrophobicContact CG2-CD1 4.3Å; I68-I72 WeakPolarHBondContact O-CG1 3.26Å; I68-I72 PolarHBondContact O-N 3.08Å; I68-I72 VanDerWaalsContact O-N 3.08Å
69	A	97.8	Very high	96.7	Very high	0 Å²	0	22.4 Å²	22.4	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-62.8	-43.6	177.2	0	0	0	0	0	111.7	W65 M66 L71 I72 Q73 S118 I121 A122	W65-A69 PolarHBondContact O-N 3.48Å; M66-A69 PolarHBondContact O-N 3.41Å; M66-A69 VanDerWaalsContact O-N 3.14Å; A69-L71 VanDerWaalsContact C-N 3.34Å; A69-L71 PolarHBondContact O-N 3.1Å; A69-I72 PolarHBondContact O-N 3.02Å; A69-Q73 PolarHBondContact O-N 3.41Å; A69-S118 WeakPolarHBondContact O-CB 3.12Å; A69-I121 HydrophobicContact CB-CB 4.48Å; A69-I121 HydrophobicContact CB-CG2 4.03Å; A69-A122 HydrophobicContact CB-CB 4.03Å
70	H	97.8	Very high	96.9	Very high	15 Å²	15	23.9 Å²	23.9	7%	0.069	12%	0.115	C	C	.	.	H	α-helix	trans	-63.3	-36.9	175.4	-71.8	178.5	0	0	0	113	M66 Q73 L74 H308 D311	M66-H70 PolarHBondContact O-N 3.47Å; H70-Q73 PolarHBondContact O-N 2.86Å; H70-L74 WeakPolarHBondContact O-CB 3.39Å; H70-L74 VanDerWaalsContact O-CG 3.3Å; H70-L74 WeakPolarHBondContact O-CG 3.38Å; H70-L74 PolarHBondContact O-N 3.26Å; H70-H308 HydrophobicContact CB-CB 3.96Å; H70-H308 AromaticContact CD2-CE1 3.84Å; H70-H308 AromaticContact CD2-CG 3.88Å; H70-H308 AromaticContact CD2-ND1 3.02Å; H70-H308 PolarHBondContact CD2-ND1 2.81Å; H70-H308 AromaticContact CE1-ND1 3.81Å; H70-H308 AromaticContact CG-ND1 3.6Å; H70-H308 AromaticContact NE2-CE1 3.88Å; H70-H308 AromaticContact NE2-ND1 3.17Å; H70-H308 PolarHBondContact NE2-ND1 3.14Å; H70-H308 VanDerWaalsContact NE2-ND1 3.17Å; H70-D311 IonicContact CE1-OD2 3.75Å; H70-D311 PolarHBondContact CE1-OD2 3.38Å; H70-D311 IonicContact ND1-OD2 2.71Å; H70-D311 PolarHBondContact ND1-OD2 2.9Å
71	L	98.2	Very high	96.9	Very high	34 Å²	34	25 Å²	25	18%	0.178	12%	0.121	C	C	.	.	H	α-helix	trans	-63.3	-43.5	174.6	-177.3	64.6	0	0	0	111.5	I38 N41 I42 I45 A67 I68 A69 Q73 L74 I75	I38-L71 HydrophobicContact CB-CD1 4.32Å; I38-L71 HydrophobicContact CG1-CD1 4.35Å; I38-L71 HydrophobicContact CG2-CD1 3.93Å; N41-L71 HydrophobicContact CB-CB 4.34Å; N41-L71 HydrophobicContact CB-CD1 4.46Å; I42-L71 HydrophobicContact CG1-CD1 4.19Å; I42-L71 HydrophobicContact CG1-CD2 4.25Å; I45-L71 HydrophobicContact CD1-CD2 4.3Å; A67-L71 VanDerWaalsContact O-CB 3.26Å; A67-L71 WeakPolarHBondContact O-CB 3.44Å; A67-L71 PolarHBondContact O-N 3.03Å; I68-L71 PolarHBondContact O-N 3.41Å; A69-L71 VanDerWaalsContact C-N 3.34Å; A69-L71 PolarHBondContact O-N 3.1Å; L71-Q73 VanDerWaalsContact C-N 3.35Å; L71-L74 PolarHBondContact O-N 3.47Å; L71-I75 HydrophobicContact CD1-CD1 3.99Å; L71-I75 HydrophobicContact CD1-CG1 4.47Å; L71-I75 HydrophobicContact CG-CD1 3.98Å; L71-I75 VanDerWaalsContact O-CG1 3.27Å; L71-I75 WeakPolarHBondContact O-CG1 3.38Å; L71-I75 PolarHBondContact O-N 3.28Å; L71-I75 VanDerWaalsContact O-N 3.07Å
72	I	97.9	Very high	96.9	Very high	58 Å²	58	24.4 Å²	24.4	30%	0.297	12%	0.118	S	C	.	.	H	α-helix	trans	-61.3	-46.1	175	-64.6	167.3	0	0	0	109.9	I68 A69 L74 I75 V76 L114	I68-I72 HydrophobicContact CG2-CD1 4.3Å; I68-I72 WeakPolarHBondContact O-CG1 3.26Å; I68-I72 PolarHBondContact O-N 3.08Å; I68-I72 VanDerWaalsContact O-N 3.08Å; A69-I72 PolarHBondContact O-N 3.02Å; I72-L74 PolarHBondContact O-N 3.47Å; I72-I75 PolarHBondContact O-N 2.93Å; I72-V76 HydrophobicContact CG2-CG2 4.11Å; I72-V76 WeakPolarHBondContact O-CB 3.44Å; I72-V76 WeakPolarHBondContact O-CG2 3.34Å; I72-V76 PolarHBondContact O-N 2.97Å; I72-L114 HydrophobicContact CG2-CB 4.42Å
73	Q	96.9	Very high	96.9	Very high	10 Å²	10	26 Å²	26	5%	0.047	13%	0.125	C	C	.	.	H	α-helix	trans	-60.8	-45.8	179.2	-163.7	65.6	17.6	0	0	112.4	A69 H70 L71 I75 N77 T78 S115 S118 H308	A69-Q73 PolarHBondContact O-N 3.41Å; H70-Q73 PolarHBondContact O-N 2.86Å; L71-Q73 VanDerWaalsContact C-N 3.35Å; Q73-I75 VanDerWaalsContact C-N 3.32Å; Q73-I75 PolarHBondContact O-N 3.32Å; Q73-N77 HydrophobicContact CG-CB 4.35Å; Q73-N77 PolarHBondContact NE2-ND2 3.16Å; Q73-N77 WeakPolarHBondContact O-CA 3.48Å; Q73-N77 WeakPolarHBondContact O-CB 3.32Å; Q73-N77 PolarHBondContact O-N 3.5Å; Q73-T78 PolarHBondContact O-N 3.43Å; Q73-S115 PolarHBondContact NE2-OG 3.43Å; Q73-S115 PolarHBondContact OE1-O 2.95Å; Q73-S118 PolarHBondContact OE1-OG 2.86Å; Q73-H308 VanDerWaalsContact CG-CD2 3.47Å; Q73-H308 WeakPolarHBondContact CG-CD2 3.46Å; Q73-H308 WeakPolarHBondContact CG-NE2 3.44Å
74	L	97.9	Very high	96.8	Very high	0 Å²	0	27.6 Å²	27.6	0%	0	13%	0.133	C	C	.	.	I	π-helix	trans	-64.3	-36.5	178.9	-74.5	167.3	0	0	0	112.4	I38 N41 H70 L71 I72 T78 F79 H308	I38-L74 HydrophobicContact CG1-CB 4.05Å; N41-L74 VanDerWaalsContact ND2-CD1 3.29Å; N41-L74 WeakPolarHBondContact ND2-CD1 3.49Å; H70-L74 WeakPolarHBondContact O-CB 3.39Å; H70-L74 VanDerWaalsContact O-CG 3.3Å; H70-L74 WeakPolarHBondContact O-CG 3.38Å; H70-L74 PolarHBondContact O-N 3.26Å; L71-L74 PolarHBondContact O-N 3.47Å; I72-L74 PolarHBondContact O-N 3.47Å; L74-T78 WeakPolarHBondContact O-CB 3.35Å; L74-T78 PolarHBondContact O-N 3.46Å; L74-F79 WeakPolarHBondContact O-CB 3.14Å; L74-F79 PolarHBondContact O-N 2.98Å; L74-H308 HydrophobicContact CD1-CB 4.2Å; L74-H308 HydrophobicContact CD2-CB 4.09Å; L74-H308 HydrophobicContact CG-CB 3.89Å
75	I	97.8	Very high	96.4	Very high	65 Å²	65	27.1 Å²	27.1	33%	0.333	13%	0.131	S	C	.	.	I	π-helix	trans	-74	-53.6	178.2	-67.3	168.7	0	0	0	110.4	I38 L71 I72 Q73 F79 I80	I38-I75 HydrophobicContact CD1-CG1 3.82Å; I38-I75 HydrophobicContact CG1-CG1 4.12Å; L71-I75 HydrophobicContact CD1-CD1 3.99Å; L71-I75 HydrophobicContact CD1-CG1 4.47Å; L71-I75 HydrophobicContact CG-CD1 3.98Å; L71-I75 VanDerWaalsContact O-CG1 3.27Å; L71-I75 WeakPolarHBondContact O-CG1 3.38Å; L71-I75 PolarHBondContact O-N 3.28Å; L71-I75 VanDerWaalsContact O-N 3.07Å; I72-I75 PolarHBondContact O-N 2.93Å; Q73-I75 VanDerWaalsContact C-N 3.32Å; Q73-I75 PolarHBondContact O-N 3.32Å; I75-F79 WeakPolarHBondContact O-CB 3.39Å; I75-I80 HydrophobicContact CG2-CD1 3.99Å; I75-I80 WeakPolarHBondContact O-CB 3.12Å; I75-I80 VanDerWaalsContact O-CG1 3.25Å; I75-I80 WeakPolarHBondContact O-CG1 3.42Å; I75-I80 PolarHBondContact O-N 3.21Å
76	V	96.5	Very high	96.1	Very high	13 Å²	13	26 Å²	26	8%	0.079	13%	0.127	C	C	.	.	I	π-helix	trans	-75.4	-48.9	-171.2	174.6	0	0	0	0	111.8	I72 I80 D81 L111 L114	I72-V76 HydrophobicContact CG2-CG2 4.11Å; I72-V76 WeakPolarHBondContact O-CB 3.44Å; I72-V76 WeakPolarHBondContact O-CG2 3.34Å; I72-V76 PolarHBondContact O-N 2.97Å; V76-I80 WeakPolarHBondContact O-CB 3.35Å; V76-D81 PolarHBondContact O-N 3.22Å; V76-D81 VanDerWaalsContact O-N 3.11Å; V76-L111 HydrophobicContact CG1-CB 4.17Å; V76-L111 HydrophobicContact CG1-CD2 3.82Å; V76-L111 VanDerWaalsContact CG1-O 3.23Å; V76-L111 WeakPolarHBondContact CG1-O 3.16Å; V76-L111 HydrophobicContact CG2-CD2 4.39Å; V76-L114 HydrophobicContact CG1-CB 4.34Å; V76-L114 HydrophobicContact CG2-CB 4.23Å; V76-L114 HydrophobicContact CG2-CD1 4.43Å
77	N	95.1	Very high	95.9	Very high	14 Å²	14	26 Å²	26	8%	0.075	13%	0.126	C	C	.	.	I	π-helix	trans	-86.2	-57	-175.8	-172.2	48.2	0	0	0	111.3	Q73 D81 D82	Q73-N77 HydrophobicContact CG-CB 4.35Å; Q73-N77 PolarHBondContact NE2-ND2 3.16Å; Q73-N77 WeakPolarHBondContact O-CA 3.48Å; Q73-N77 WeakPolarHBondContact O-CB 3.32Å; Q73-N77 PolarHBondContact O-N 3.5Å; N77-D81 WeakPolarHBondContact O-CB 3.48Å; N77-D81 PolarHBondContact O-N 2.78Å; N77-D82 WeakPolarHBondContact O-CB 3.47Å; N77-D82 PolarHBondContact O-N 3.18Å
78	T	96.8	Very high	95.6	Very high	0 Å²	0	27.5 Å²	27.5	0%	0	13%	0.134	C	C	.	.	I	π-helix	trans	-75.7	-43.6	-171	-45.5	0	0	0	0	113.2	S30 L33 Q73 L74 D82 F83 S305	S30-T78 WeakPolarHBondContact O-CG2 3.3Å; L33-T78 HydrophobicContact CB-CG2 4.29Å; Q73-T78 PolarHBondContact O-N 3.43Å; L74-T78 WeakPolarHBondContact O-CB 3.35Å; L74-T78 PolarHBondContact O-N 3.46Å; T78-D82 WeakPolarHBondContact O-CB 3.23Å; T78-F83 PolarHBondContact O-N 3.32Å; T78-F83 VanDerWaalsContact O-N 3.16Å; T78-S305 WeakPolarHBondContact OG1-CB 3.44Å; T78-S305 PolarHBondContact OG1-OG 3.36Å
79	F	97.2	Very high	95.3	Very high	75 Å²	75	28.2 Å²	28.2	33%	0.329	14%	0.135	S	C	.	.	I	π-helix	trans	-84.8	-53	-177.3	-176	-112.8	0	0	0	112.3	L74 I75 F83 L84	L74-F79 WeakPolarHBondContact O-CB 3.14Å; L74-F79 PolarHBondContact O-N 2.98Å; I75-F79 WeakPolarHBondContact O-CB 3.39Å; F79-F83 HydrophobicContact CD2-CD1 4.12Å; F79-F83 AromaticContact CE2-CD1 3.99Å; F79-F83 HydrophobicContact CE2-CD1 3.99Å; F79-F83 HydrophobicContact CE2-CE1 4.36Å; F79-F83 WeakPolarHBondContact O-CB 3.24Å; F79-L84 HydrophobicContact CD1-CD1 4.3Å; F79-L84 HydrophobicContact CE1-CD1 3.89Å; F79-L84 HydrophobicContact CZ-CD1 4.2Å; F79-L84 HydrophobicContact CZ-CG 4.49Å; F79-L84 WeakPolarHBondContact O-CG 3.32Å; F79-L84 PolarHBondContact O-N 3.23Å
80	I	96	Very high	95	Very high	33 Å²	33	30 Å²	30	17%	0.169	14%	0.142	C	C	.	.	I	π-helix	trans	-76.8	-55.7	-175.8	-65.6	168.7	0	0	0	111.9	I75 V76 L84 G85 V100 L111	I75-I80 HydrophobicContact CG2-CD1 3.99Å; I75-I80 WeakPolarHBondContact O-CB 3.12Å; I75-I80 VanDerWaalsContact O-CG1 3.25Å; I75-I80 WeakPolarHBondContact O-CG1 3.42Å; I75-I80 PolarHBondContact O-N 3.21Å; V76-I80 WeakPolarHBondContact O-CB 3.35Å; I80-L84 WeakPolarHBondContact O-CB 3.39Å; I80-G85 PolarHBondContact O-N 3.02Å; I80-V100 HydrophobicContact CG2-CB 3.7Å; I80-V100 HydrophobicContact CG2-CG1 4.17Å; I80-V100 HydrophobicContact CG2-CG2 3.86Å; I80-L111 HydrophobicContact CD1-CD2 4.3Å; I80-L111 HydrophobicContact CG2-CD1 3.98Å; I80-L111 HydrophobicContact CG2-CD2 4.27Å
81	D	93.6	Very high	94.7	Very high	34 Å²	34	31 Å²	31	18%	0.182	15%	0.153	C	C	.	.	I	π-helix	trans	-75	-55.7	-176.3	-176.1	42.8	0	0	0	112.7	V76 N77 G85 R86	V76-D81 PolarHBondContact O-N 3.22Å; V76-D81 VanDerWaalsContact O-N 3.11Å; N77-D81 WeakPolarHBondContact O-CB 3.48Å; N77-D81 PolarHBondContact O-N 2.78Å; D81-G85 WeakPolarHBondContact O-CA 3.48Å; D81-G85 PolarHBondContact O-N 3.5Å; D81-R86 VanDerWaalsContact CG-NH1 3.25Å; D81-R86 PolarHBondContact O-N 3.46Å; D81-R86 IonicContact OD1-CZ 2.84Å; D81-R86 IonicContact OD1-NE 3.16Å; D81-R86 IonicContact OD1-NH1 2.75Å; D81-R86 PolarHBondContact OD1-NH1 3.23Å; D81-R86 VanDerWaalsContact OD1-NH1 3.1Å; D81-R86 IonicContact OD1-NH2 2.94Å; D81-R86 PolarHBondContact OD1-NH2 3.42Å; D81-R86 IonicContact OD2-CZ 3.86Å; D81-R86 IonicContact OD2-NH1 2.81Å; D81-R86 PolarHBondContact OD2-NH1 3.45Å; D81-R86 IonicContact OD2-NH2 2.8Å
82	D	94.8	Very high	94.4	Very high	1 Å²	1	30.7 Å²	30.7	1%	0.005	15%	0.153	C	C	.	.	I	π-helix	trans	-68.7	-59.2	-175.1	-84.2	-14.3	0	0	0	111.8	R26 N77 T78 R86 G87	R26-D82 HydrophobicContact CB-CB 4.48Å; R26-D82 HydrophobicContact CG-CB 3.95Å; R26-D82 IonicContact CZ-OD1 3.91Å; R26-D82 IonicContact NE-OD1 2.69Å; R26-D82 PolarHBondContact NE-OD1 3.16Å; R26-D82 IonicContact NH2-OD1 3.95Å; R26-D82 PolarHBondContact NH2-OD1 3.08Å; N77-D82 WeakPolarHBondContact O-CB 3.47Å; N77-D82 PolarHBondContact O-N 3.18Å; T78-D82 WeakPolarHBondContact O-CB 3.23Å; D82-R86 PolarHBondContact O-N 3.33Å; D82-G87 PolarHBondContact O-N 2.95Å
83	F	95.9	Very high	93.9	Very high	38 Å²	38	32.2 Å²	32.2	17%	0.167	16%	0.162	C	C	.	.	I	π-helix	trans	-75.1	-65.1	-176.3	175.2	-118.3	0	0	0	112.5	P31 T78 F79 G85 G87 L88	P31-F83 HydrophobicContact CB-CB 4.42Å; P31-F83 HydrophobicContact CB-CD1 4.11Å; P31-F83 HydrophobicContact CB-CD2 3.62Å; P31-F83 HydrophobicContact CB-CE1 4.27Å; P31-F83 HydrophobicContact CB-CE2 3.8Å; P31-F83 HydrophobicContact CB-CG 3.78Å; P31-F83 HydrophobicContact CB-CZ 4.11Å; P31-F83 HydrophobicContact CG-CD2 3.53Å; P31-F83 HydrophobicContact CG-CE2 3.74Å; P31-F83 HydrophobicContact CG-CG 4.15Å; T78-F83 PolarHBondContact O-N 3.32Å; T78-F83 VanDerWaalsContact O-N 3.16Å; F79-F83 HydrophobicContact CD2-CD1 4.12Å; F79-F83 AromaticContact CE2-CD1 3.99Å; F79-F83 HydrophobicContact CE2-CD1 3.99Å; F79-F83 HydrophobicContact CE2-CE1 4.36Å; F79-F83 WeakPolarHBondContact O-CB 3.24Å; F83-G85 PolarHBondContact O-N 3.42Å; F83-G87 CarbonylContact O-C 3.27Å; F83-G87 WeakPolarHBondContact O-CA 3.33Å; F83-G87 PolarHBondContact O-N 3.27Å; F83-L88 HydrophobicContact CE2-CD1 4.43Å; F83-L88 HydrophobicContact CZ-CD1 4.14Å; F83-L88 PolarHBondContact O-N 3.38Å
84	L	94.1	Very high	93.4	Very high	32 Å²	32	33.2 Å²	33.2	17%	0.168	17%	0.169	C	C	.	.	I	π-helix	trans	-64.8	-44.7	-174.7	-67.5	178.4	0	0	0	112.2	F79 I80 L88 Y98	F79-L84 HydrophobicContact CD1-CD1 4.3Å; F79-L84 HydrophobicContact CE1-CD1 3.89Å; F79-L84 HydrophobicContact CZ-CD1 4.2Å; F79-L84 HydrophobicContact CZ-CG 4.49Å; F79-L84 WeakPolarHBondContact O-CG 3.32Å; F79-L84 PolarHBondContact O-N 3.23Å; I80-L84 WeakPolarHBondContact O-CB 3.39Å; L84-L88 HydrophobicContact CD2-CD2 4.3Å; L84-Y98 CarbonylContact C-O 3.59Å; L84-Y98 VanDerWaalsContact C-O 3.27Å; L84-Y98 HydrophobicContact CB-CD1 4.24Å; L84-Y98 HydrophobicContact CD1-CD1 4.29Å; L84-Y98 HydrophobicContact CD1-CE1 4.4Å
85	G	90.1	Very high	92.9	Very high	2 Å²	2	38.8 Å²	38.8	2%	0.021	20%	0.198	C	C	.	.	I	π-helix	trans	-66.7	-44.5	-176.4	0	0	0	0	0	114.1	I80 D81 F83 Y98	I80-G85 PolarHBondContact O-N 3.02Å; D81-G85 WeakPolarHBondContact O-CA 3.48Å; D81-G85 PolarHBondContact O-N 3.5Å; F83-G85 PolarHBondContact O-N 3.42Å; G85-Y98 WeakPolarHBondContact CA-O 3.29Å
86	R	89.8	Confident	92.4	Very high	67 Å²	67	40.2 Å²	40.2	25%	0.253	21%	0.206	S	C	.	.	I	π-helix	trans	-127.6	-38.6	-169.2	-61.1	178.6	-168.7	119.1	8.7	114	Y23 D81 D82 W90	Y23-R86 HydrophobicContact CD1-CB 4.43Å; Y23-R86 HydrophobicContact CE1-CB 4.14Å; D81-R86 VanDerWaalsContact CG-NH1 3.25Å; D81-R86 PolarHBondContact O-N 3.46Å; D81-R86 IonicContact OD1-CZ 2.84Å; D81-R86 IonicContact OD1-NE 3.16Å; D81-R86 IonicContact OD1-NH1 2.75Å; D81-R86 PolarHBondContact OD1-NH1 3.23Å; D81-R86 VanDerWaalsContact OD1-NH1 3.1Å; D81-R86 IonicContact OD1-NH2 2.94Å; D81-R86 PolarHBondContact OD1-NH2 3.42Å; D81-R86 IonicContact OD2-CZ 3.86Å; D81-R86 IonicContact OD2-NH1 2.81Å; D81-R86 PolarHBondContact OD2-NH1 3.45Å; D81-R86 IonicContact OD2-NH2 2.8Å; D82-R86 PolarHBondContact O-N 3.33Å; R86-W90 PolarHBondContact O-N 3.05Å
87	G	92.8	Very high	91.8	Very high	0 Å²	0	44.7 Å²	44.7	0%	0	22%	0.221	C	C	.	.	I	π-helix	trans	-67.7	-41.8	-178.9	0	0	0	0	0	113.4	A27 D82 F83 K89 W90 A91	A27-G87 VanDerWaalsContact CB-O 3.3Å; A27-G87 WeakPolarHBondContact CB-O 3.36Å; D82-G87 PolarHBondContact O-N 2.95Å; F83-G87 CarbonylContact O-C 3.27Å; F83-G87 WeakPolarHBondContact O-CA 3.33Å; F83-G87 PolarHBondContact O-N 3.27Å; G87-K89 VanDerWaalsContact C-N 3.34Å; G87-K89 PolarHBondContact O-N 2.86Å; G87-W90 WeakPolarHBondContact O-CB 3.33Å; G87-W90 PolarHBondContact O-N 3.46Å; G87-W90 VanDerWaalsContact O-N 3.17Å; G87-A91 WeakPolarHBondContact O-CB 3.33Å; G87-A91 PolarHBondContact O-N 3.3Å
88	L	92.8	Very high	91.4	Very high	35 Å²	35	50.4 Å²	50.4	18%	0.183	24%	0.243	C	C	.	.	H	α-helix	trans	-66.4	-38	-178.9	-172.3	65.9	0	0	0	111.7	F83 L84 W90 A91 T92 I96	F83-L88 HydrophobicContact CE2-CD1 4.43Å; F83-L88 HydrophobicContact CZ-CD1 4.14Å; F83-L88 PolarHBondContact O-N 3.38Å; L84-L88 HydrophobicContact CD2-CD2 4.3Å; L88-W90 VanDerWaalsContact C-N 3.29Å; L88-W90 PolarHBondContact O-N 2.86Å; L88-A91 PolarHBondContact O-N 3Å; L88-T92 HydrophobicContact CD1-CG2 4.08Å; L88-T92 HydrophobicContact CG-CG2 4.45Å; L88-T92 WeakPolarHBondContact O-CB 3.24Å; L88-T92 WeakPolarHBondContact O-CG2 3.32Å; L88-T92 PolarHBondContact O-N 3.41Å; L88-T92 PolarHBondContact O-OG1 3.19Å; L88-I96 HydrophobicContact CD2-CG2 3.84Å; L88-I96 HydrophobicContact CG-CG2 4.34Å
89	K	90.9	Very high	90.9	Very high	66 Å²	66	52 Å²	52	29%	0.287	25%	0.25	S	S	.	.	H	α-helix	trans	-58.4	-43.3	172.9	-177.6	178.6	177.7	176.9	0	111	G87 C94 I96 W97	G87-K89 VanDerWaalsContact C-N 3.34Å; G87-K89 PolarHBondContact O-N 2.86Å; K89-C94 HydrophobicContact CG-CB 4.39Å; K89-C94 WeakPolarHBondContact O-CA 3.47Å; K89-C94 PolarHBondContact O-N 3.41Å; K89-I96 WeakPolarHBondContact CA-O 3.4Å; K89-W97 HydrophobicContact CD-CG 4.31Å
90	W	91.1	Very high	90.5	Very high	37 Å²	37	49.7 Å²	49.7	14%	0.14	24%	0.242	C	C	.	.	H	α-helix	trans	-69.3	-49	176.2	178.3	-99.2	0	0	0	112.6	L12 L15 I20 Y23 N24 A27 R86 G87 L88 T92 N93	L12-W90 HydrophobicContact CB-CZ3 4.3Å; L12-W90 HydrophobicContact CD1-CE3 4.34Å; L12-W90 HydrophobicContact CD1-CZ3 4.05Å; L12-W90 HydrophobicContact CD2-CE3 3.57Å; L12-W90 HydrophobicContact CD2-CZ3 3.55Å; L12-W90 HydrophobicContact CG-CZ3 4.16Å; L15-W90 HydrophobicContact CD1-CE3 4.17Å; L15-W90 HydrophobicContact CD1-CH2 4.27Å; L15-W90 HydrophobicContact CD1-CZ3 3.4Å; I20-W90 HydrophobicContact CG1-CH2 4.12Å; I20-W90 HydrophobicContact CG2-CH2 4.22Å; I20-W90 HydrophobicContact CG2-CZ2 4.1Å; Y23-W90 HydrophobicContact CD1-CB 4.41Å; Y23-W90 HydrophobicContact CD2-CE3 4.15Å; Y23-W90 HydrophobicContact CG-CB 4.36Å; Y23-W90 HydrophobicContact CG-CD2 4.33Å; Y23-W90 HydrophobicContact CG-CE3 4.15Å; Y23-W90 HydrophobicContact CG-CG 4.44Å; N24-W90 PolarHBondContact OD1-NE1 2.81Å; A27-W90 HydrophobicContact CB-CB 4.33Å; A27-W90 HydrophobicContact CB-CG 4.34Å; R86-W90 PolarHBondContact O-N 3.05Å; G87-W90 WeakPolarHBondContact O-CB 3.33Å; G87-W90 PolarHBondContact O-N 3.46Å; G87-W90 VanDerWaalsContact O-N 3.17Å; L88-W90 VanDerWaalsContact C-N 3.29Å; L88-W90 PolarHBondContact O-N 2.86Å; W90-T92 PolarHBondContact O-N 3.12Å; W90-T92 VanDerWaalsContact O-N 3.17Å; W90-N93 PolarHBondContact O-N 3.18Å; W90-N93 VanDerWaalsContact O-N 3.11Å
91	A	92.6	Very high	90	Very high	37 Å²	37	48.7 Å²	48.7	31%	0.306	24%	0.237	S	C	.	.	H	α-helix	trans	-59	-31	-178	0	0	0	0	0	113.4	A27 G87 L88	A27-A91 HydrophobicContact CB-CB 4.13Å; G87-A91 WeakPolarHBondContact O-CB 3.33Å; G87-A91 PolarHBondContact O-N 3.3Å; L88-A91 PolarHBondContact O-N 3Å
92	T	92.3	Very high	89.7	Confident	28 Å²	28	47.8 Å²	47.8	17%	0.172	23%	0.234	C	C	.	.	T	Hydrogen-bonded Turn	trans	-98.5	14.6	-177.7	63	0	0	0	0	113.2	L88 W90 C94 L95 I96	L88-T92 HydrophobicContact CD1-CG2 4.08Å; L88-T92 HydrophobicContact CG-CG2 4.45Å; L88-T92 WeakPolarHBondContact O-CB 3.24Å; L88-T92 WeakPolarHBondContact O-CG2 3.32Å; L88-T92 PolarHBondContact O-N 3.41Å; L88-T92 PolarHBondContact O-OG1 3.19Å; W90-T92 PolarHBondContact O-N 3.12Å; W90-T92 VanDerWaalsContact O-N 3.17Å; T92-C94 PolarHBondContact O-N 3.37Å; T92-L95 WeakPolarHBondContact O-CB 3.28Å; T92-L95 WeakPolarHBondContact O-CD1 3.39Å; T92-L95 WeakPolarHBondContact O-CG 3.19Å; T92-L95 PolarHBondContact O-N 3.31Å; T92-I96 HydrophobicContact CG2-CB 4.13Å; T92-I96 HydrophobicContact CG2-CD1 4.15Å; T92-I96 HydrophobicContact CG2-CG1 4.2Å; T92-I96 PolarHBondContact OG1-N 3.34Å; T92-I96 PolarHBondContact OG1-O 3.47Å
93	N	87.8	Confident	89.4	Confident	90 Å²	90	57.3 Å²	57.3	48%	0.481	27%	0.271	S	S	.	.	T	Hydrogen-bonded Turn	trans	50.4	44.5	-175.2	-63.9	-41.1	0	0	0	112.4	L8 W90 L95	L8-N93 VanDerWaalsContact CD1-O 3.22Å; L8-N93 WeakPolarHBondContact CD1-O 3.26Å; L8-N93 HydrophobicContact CD2-CB 4.45Å; L8-N93 VanDerWaalsContact CG-O 3.26Å; L8-N93 WeakPolarHBondContact CG-O 3.19Å; W90-N93 PolarHBondContact O-N 3.18Å; W90-N93 VanDerWaalsContact O-N 3.11Å; N93-L95 VanDerWaalsContact C-N 3.25Å; N93-L95 PolarHBondContact O-N 2.85Å
94	C	85.8	Confident	89.2	Confident	30 Å²	30	57.2 Å²	57.2	20%	0.203	28%	0.275	C	S	.	.	T	Hydrogen-bonded Turn	trans	62.7	20.3	-177.2	-52.9	0	0	0	0	115.6	C11 K89 T92	C11-C94 HydrophobicContact CB-CB 3.67Å; C11-C94 WeakPolarHBondContact CB-SG 3.38Å; C11-C94 WeakPolarHBondContact SG-CB 3.34Å; C11-C94 CovalentContact SG-SG 2.04Å; C11-C94 PolarHBondContact SG-SG 3.34Å; K89-C94 HydrophobicContact CG-CB 4.39Å; K89-C94 WeakPolarHBondContact O-CA 3.47Å; K89-C94 PolarHBondContact O-N 3.41Å; T92-C94 PolarHBondContact O-N 3.37Å
95	L	86.6	Confident	89.1	Confident	117 Å²	117	57.5 Å²	57.5	61%	0.613	28%	0.28	S	S	*	.	S	Bend	trans	-75.6	-38.5	173.2	-68.2	169	0	0	0	112.8	L8 T92 N93	L8-L95 HydrophobicContact CD1-CD2 3.48Å; L8-L95 VanDerWaalsContact CD1-CD2 3.48Å; L8-L95 HydrophobicContact CD1-CG 3.91Å; L8-L95 HydrophobicContact CD2-CD2 4.03Å; L8-L95 HydrophobicContact CD2-CG 4.27Å; L8-L95 HydrophobicContact CG-CD2 4.42Å; T92-L95 WeakPolarHBondContact O-CB 3.28Å; T92-L95 WeakPolarHBondContact O-CD1 3.39Å; T92-L95 WeakPolarHBondContact O-CG 3.19Å; T92-L95 PolarHBondContact O-N 3.31Å; N93-L95 VanDerWaalsContact C-N 3.25Å; N93-L95 PolarHBondContact O-N 2.85Å
96	I	88.3	Confident	89.3	Confident	96 Å²	96	62.9 Å²	62.9	49%	0.492	31%	0.308	S	S	.	.			trans	-121.9	121.2	-177.5	-54.5	-179.9	0	0	0	108.7	L88 K89 T92	L88-I96 HydrophobicContact CD2-CG2 3.84Å; L88-I96 HydrophobicContact CG-CG2 4.34Å; K89-I96 WeakPolarHBondContact CA-O 3.4Å; T92-I96 HydrophobicContact CG2-CB 4.13Å; T92-I96 HydrophobicContact CG2-CD1 4.15Å; T92-I96 HydrophobicContact CG2-CG1 4.2Å; T92-I96 PolarHBondContact OG1-N 3.34Å; T92-I96 PolarHBondContact OG1-O 3.47Å
97	W	83.1	Confident	89.5	Confident	107 Å²	107	61.5 Å²	61.5	41%	0.405	31%	0.306	S	S	.	.			trans	-126.4	119.4	176.3	176.5	18.6	0	0	0	109.7	K89 Q99 T183	K89-W97 HydrophobicContact CD-CG 4.31Å; W97-Q99 VanDerWaalsContact CZ2-OE1 3.24Å; W97-Q99 VanDerWaalsContact NE1-OE1 3.09Å; W97-T183 HydrophobicContact CH2-CG2 3.73Å; W97-T183 HydrophobicContact CZ3-CG2 4.14Å
98	Y	87.1	Confident	89.5	Confident	134 Å²	134	61.5 Å²	61.5	53%	0.525	31%	0.306	S	S	.	.			trans	-131.7	82.9	177.8	-170	-109.1	0	0	0	110.9	L84 G85 V100	L84-Y98 CarbonylContact C-O 3.59Å; L84-Y98 VanDerWaalsContact C-O 3.27Å; L84-Y98 HydrophobicContact CB-CD1 4.24Å; L84-Y98 HydrophobicContact CD1-CD1 4.29Å; L84-Y98 HydrophobicContact CD1-CE1 4.4Å; G85-Y98 WeakPolarHBondContact CA-O 3.29Å; Y98-V100 HydrophobicContact CD1-CG2 3.57Å; Y98-V100 HydrophobicContact CE1-CG2 3.11Å; Y98-V100 PolarHBondContact O-N 2.89Å
99	Q	86.3	Confident	89.6	Confident	32 Å²	32	62 Å²	62	15%	0.15	31%	0.307	C	S	.	.			trans	-88.4	100	171.5	-108.3	-172.9	-80.2	0	0	111.1	W97 D101 S102	W97-Q99 VanDerWaalsContact CZ2-OE1 3.24Å; W97-Q99 VanDerWaalsContact NE1-OE1 3.09Å; Q99-D101 VanDerWaalsContact C-N 3.31Å; Q99-D101 VanDerWaalsContact CB-OD1 3.23Å; Q99-D101 WeakPolarHBondContact CB-OD1 3.23Å; Q99-D101 WeakPolarHBondContact CG-OD1 3.33Å; Q99-D101 PolarHBondContact NE2-OD1 3.48Å; Q99-D101 PolarHBondContact NE2-OD2 3.16Å; Q99-S102 PolarHBondContact NE2-OG 3.4Å; Q99-S102 VanDerWaalsContact NE2-OG 3.08Å; Q99-S102 PolarHBondContact O-N 2.96Å
100	V	88.1	Confident	89.9	Confident	27 Å²	27	62.3 Å²	62.3	16%	0.164	31%	0.312	C	S	.	.	S	Bend	trans	-67.7	-34.3	178.6	-173.1	0	0	0	0	112	I80 Y98 S102 Y103 T107 L111	I80-V100 HydrophobicContact CG2-CB 3.7Å; I80-V100 HydrophobicContact CG2-CG1 4.17Å; I80-V100 HydrophobicContact CG2-CG2 3.86Å; Y98-V100 HydrophobicContact CD1-CG2 3.57Å; Y98-V100 HydrophobicContact CE1-CG2 3.11Å; Y98-V100 PolarHBondContact O-N 2.89Å; V100-S102 PolarHBondContact O-N 3.29Å; V100-Y103 WeakPolarHBondContact O-CB 3.2Å; V100-Y103 PolarHBondContact O-N 3.41Å; V100-T107 WeakPolarHBondContact O-CB 3.42Å; V100-T107 PolarHBondContact O-OG1 3.42Å; V100-L111 HydrophobicContact CB-CD1 4.18Å; V100-L111 HydrophobicContact CG1-CD1 3.97Å
101	D	86.3	Confident	90	Very high	13 Å²	13	61.9 Å²	61.9	7%	0.07	31%	0.312	C	S	.	.	T	Hydrogen-bonded Turn	trans	-61.2	-33.1	174.6	64.6	-31.7	0	0	0	111.9	Q99 C108 L111 C186	Q99-D101 VanDerWaalsContact C-N 3.31Å; Q99-D101 VanDerWaalsContact CB-OD1 3.23Å; Q99-D101 WeakPolarHBondContact CB-OD1 3.23Å; Q99-D101 WeakPolarHBondContact CG-OD1 3.33Å; Q99-D101 PolarHBondContact NE2-OD1 3.48Å; Q99-D101 PolarHBondContact NE2-OD2 3.16Å; D101-C108 WeakPolarHBondContact O-CA 3.41Å; D101-C108 VanDerWaalsContact O-CB 3.27Å; D101-C108 WeakPolarHBondContact O-CB 3.18Å; D101-C108 PolarHBondContact O-N 3.07Å; D101-L111 HydrophobicContact CB-CD1 4.2Å; D101-C186 HydrophobicContact CB-CB 3.98Å
102	S	87.3	Confident	90	Very high	15 Å²	15	61.8 Å²	61.8	11%	0.105	31%	0.307	C	S	.	.	T	Hydrogen-bonded Turn	trans	-84.6	-5.3	179.5	-63.8	0	0	0	0	115.5	Q99 V100 T184	Q99-S102 PolarHBondContact NE2-OG 3.4Å; Q99-S102 VanDerWaalsContact NE2-OG 3.08Å; Q99-S102 PolarHBondContact O-N 2.96Å; V100-S102 PolarHBondContact O-N 3.29Å; S102-T184 VanDerWaalsContact CB-O 3.29Å; S102-T184 WeakPolarHBondContact CB-O 3.39Å; S102-T184 PolarHBondContact OG-O 2.91Å
103	Y	88.6	Confident	90.2	Very high	200 Å²	200	61.7 Å²	61.7	78%	0.784	30%	0.304	S	S	*	.	S	Bend	trans	-67.8	-38.9	-175.3	-172.7	-101.9	0	0	0	113	V100	V100-Y103 WeakPolarHBondContact O-CB 3.2Å; V100-Y103 PolarHBondContact O-N 3.41Å
104	S	92.3	Very high	90.6	Very high	36 Å²	36	60.6 Å²	60.6	25%	0.252	30%	0.298	S	S	.	.			trans	-154.1	156.9	-180	71.2	0	0	0	0	111.2	L106 T107 C108	S104-L106 PolarHBondContact O-N 3.09Å; S104-T107 PolarHBondContact N-OG1 2.89Å; S104-T107 PolarHBondContact O-N 2.85Å; S104-T107 PolarHBondContact O-OG1 3.19Å; S104-T107 WeakPolarHBondContact OG-CB 3.27Å; S104-T107 WeakPolarHBondContact OG-CG2 3.26Å; S104-T107 PolarHBondContact OG-N 3.33Å; S104-T107 PolarHBondContact OG-OG1 3.02Å; S104-C108 PolarHBondContact O-N 3.44Å
105	S	92.2	Very high	91.1	Very high	39 Å²	39	59.9 Å²	59.9	27%	0.273	29%	0.293	S	S	.	.	H	α-helix	trans	-57	-36.8	173.5	-179.7	0	0	0	0	111.5	K109 D175	S105-K109 WeakPolarHBondContact O-CB 3.14Å; S105-K109 VanDerWaalsContact O-CG 3.31Å; S105-K109 WeakPolarHBondContact O-CG 3.43Å; S105-K109 PolarHBondContact O-N 3.15Å; S105-K109 PolarHBondContact OG-NZ 3.13Å; S105-D175 VanDerWaalsContact CB-OD1 3.26Å; S105-D175 WeakPolarHBondContact CB-OD1 3.35Å; S105-D175 VanDerWaalsContact OG-CG 3.29Å; S105-D175 PolarHBondContact OG-OD1 3.49Å; S105-D175 PolarHBondContact OG-OD2 3.12Å
106	L	94	Very high	91.4	Very high	115 Å²	115	55.6 Å²	55.6	60%	0.602	27%	0.271	S	S	*	.	H	α-helix	trans	-65.8	-44.2	178.1	-176.9	65.5	0	0	0	112.1	S104 K109 L110	S104-L106 PolarHBondContact O-N 3.09Å; L106-K109 PolarHBondContact O-N 3Å; L106-L110 HydrophobicContact CD1-CD1 3.89Å; L106-L110 HydrophobicContact CD1-CG 4.07Å; L106-L110 HydrophobicContact CD2-CD1 4.44Å; L106-L110 HydrophobicContact CG-CD1 3.82Å; L106-L110 HydrophobicContact CG-CG 4.34Å; L106-L110 WeakPolarHBondContact O-CB 3.35Å; L106-L110 VanDerWaalsContact O-CG 3.3Å; L106-L110 WeakPolarHBondContact O-CG 3.36Å; L106-L110 PolarHBondContact O-N 3.45Å
107	T	93.4	Very high	91.8	Very high	37 Å²	37	51.3 Å²	51.3	23%	0.227	25%	0.249	C	C	.	.	H	α-helix	trans	-68	-41	179.2	51.3	0	0	0	0	111.7	V100 S104 L110 L111	V100-T107 WeakPolarHBondContact O-CB 3.42Å; V100-T107 PolarHBondContact O-OG1 3.42Å; S104-T107 PolarHBondContact N-OG1 2.89Å; S104-T107 PolarHBondContact O-N 2.85Å; S104-T107 PolarHBondContact O-OG1 3.19Å; S104-T107 WeakPolarHBondContact OG-CB 3.27Å; S104-T107 WeakPolarHBondContact OG-CG2 3.26Å; S104-T107 PolarHBondContact OG-N 3.33Å; S104-T107 PolarHBondContact OG-OG1 3.02Å; T107-L110 PolarHBondContact O-N 3.46Å; T107-L111 WeakPolarHBondContact O-CB 3.24Å; T107-L111 VanDerWaalsContact O-CG 3.25Å; T107-L111 WeakPolarHBondContact O-CG 3.41Å; T107-L111 PolarHBondContact O-N 3.34Å
108	C	93.6	Very high	92.5	Very high	0 Å²	0	46.3 Å²	46.3	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-53.7	-55.7	171	171.2	0	0	0	0	111.1	D101 S104 L110 T112 L176 C186	D101-C108 WeakPolarHBondContact O-CA 3.41Å; D101-C108 VanDerWaalsContact O-CB 3.27Å; D101-C108 WeakPolarHBondContact O-CB 3.18Å; D101-C108 PolarHBondContact O-N 3.07Å; S104-C108 PolarHBondContact O-N 3.44Å; C108-L110 PolarHBondContact O-N 3.49Å; C108-T112 PolarHBondContact O-N 3.34Å; C108-T112 VanDerWaalsContact O-N 3.14Å; C108-T112 PolarHBondContact O-OG1 3.44Å; C108-T112 VanDerWaalsContact O-OG1 3.08Å; C108-L176 HydrophobicContact CB-CD2 4.39Å; C108-C186 WeakPolarHBondContact CA-SG 3.27Å; C108-C186 HydrophobicContact CB-CB 3.8Å; C108-C186 WeakPolarHBondContact CB-SG 3.09Å; C108-C186 VanDerWaalsContact SG-CA 3.58Å; C108-C186 WeakPolarHBondContact SG-CB 3.46Å; C108-C186 CovalentContact SG-SG 2.03Å; C108-C186 PolarHBondContact SG-SG 2.87Å
109	K	94.8	Very high	92.8	Very high	45 Å²	45	40.3 Å²	40.3	20%	0.196	21%	0.209	C	C	.	.	H	α-helix	trans	-58.6	-48.5	-179.9	-75.6	167.3	177.4	155.4	0	112.5	S105 L106 Y113 L171 A174 D175	S105-K109 WeakPolarHBondContact O-CB 3.14Å; S105-K109 VanDerWaalsContact O-CG 3.31Å; S105-K109 WeakPolarHBondContact O-CG 3.43Å; S105-K109 PolarHBondContact O-N 3.15Å; S105-K109 PolarHBondContact OG-NZ 3.13Å; L106-K109 PolarHBondContact O-N 3Å; K109-Y113 WeakPolarHBondContact O-CB 3.24Å; K109-Y113 PolarHBondContact O-N 2.84Å; K109-L171 HydrophobicContact CB-CD2 4.12Å; K109-L171 VanDerWaalsContact CD-O 3.3Å; K109-L171 WeakPolarHBondContact CD-O 3.33Å; K109-L171 WeakPolarHBondContact CE-O 3.22Å; K109-A174 WeakPolarHBondContact CE-O 3.45Å; K109-A174 WeakPolarHBondContact CG-O 3.27Å; K109-D175 WeakPolarHBondContact CE-OD2 3.4Å; K109-D175 IonicContact NZ-OD1 2.72Å; K109-D175 IonicContact NZ-OD2 3.5Å; K109-D175 PolarHBondContact NZ-OD2 3.48Å
110	L	95.5	Very high	93.3	Very high	74 Å²	74	38.9 Å²	38.9	39%	0.387	20%	0.202	S	C	.	.	H	α-helix	trans	-69.4	-42	-176.6	-73.6	177.1	0	0	0	112.9	L106 T107 C108 Y113 L114 L171	L106-L110 HydrophobicContact CD1-CD1 3.89Å; L106-L110 HydrophobicContact CD1-CG 4.07Å; L106-L110 HydrophobicContact CD2-CD1 4.44Å; L106-L110 HydrophobicContact CG-CD1 3.82Å; L106-L110 HydrophobicContact CG-CG 4.34Å; L106-L110 WeakPolarHBondContact O-CB 3.35Å; L106-L110 VanDerWaalsContact O-CG 3.3Å; L106-L110 WeakPolarHBondContact O-CG 3.36Å; L106-L110 PolarHBondContact O-N 3.45Å; T107-L110 PolarHBondContact O-N 3.46Å; C108-L110 PolarHBondContact O-N 3.49Å; L110-Y113 PolarHBondContact O-N 2.96Å; L110-L114 VanDerWaalsContact O-CB 3.26Å; L110-L114 WeakPolarHBondContact O-CB 3.37Å; L110-L114 VanDerWaalsContact O-CG 3.22Å; L110-L114 WeakPolarHBondContact O-CG 3.37Å; L110-L114 PolarHBondContact O-N 3.38Å; L110-L171 HydrophobicContact CD2-CD2 4.37Å
111	L	94.8	Very high	93.7	Very high	28 Å²	28	37.9 Å²	37.9	15%	0.147	20%	0.196	C	C	.	.	H	α-helix	trans	-67.9	-44.3	-179.3	-69.1	172.8	0	0	0	111.2	V76 I80 V100 D101 T107 S115	V76-L111 HydrophobicContact CG1-CB 4.17Å; V76-L111 HydrophobicContact CG1-CD2 3.82Å; V76-L111 VanDerWaalsContact CG1-O 3.23Å; V76-L111 WeakPolarHBondContact CG1-O 3.16Å; V76-L111 HydrophobicContact CG2-CD2 4.39Å; I80-L111 HydrophobicContact CD1-CD2 4.3Å; I80-L111 HydrophobicContact CG2-CD1 3.98Å; I80-L111 HydrophobicContact CG2-CD2 4.27Å; V100-L111 HydrophobicContact CB-CD1 4.18Å; V100-L111 HydrophobicContact CG1-CD1 3.97Å; D101-L111 HydrophobicContact CB-CD1 4.2Å; T107-L111 WeakPolarHBondContact O-CB 3.24Å; T107-L111 VanDerWaalsContact O-CG 3.25Å; T107-L111 WeakPolarHBondContact O-CG 3.41Å; T107-L111 PolarHBondContact O-N 3.34Å; L111-S115 WeakPolarHBondContact O-CB 3.4Å; L111-S115 PolarHBondContact O-N 3.26Å
112	T	92.9	Very high	94.2	Very high	34 Å²	34	37.6 Å²	37.6	21%	0.209	20%	0.195	C	C	.	.	H	α-helix	trans	-61.1	-48.2	174.1	-56	0	0	0	0	110.9	C108 L114 S115 D116 A174	C108-T112 PolarHBondContact O-N 3.34Å; C108-T112 VanDerWaalsContact O-N 3.14Å; C108-T112 PolarHBondContact O-OG1 3.44Å; C108-T112 VanDerWaalsContact O-OG1 3.08Å; T112-L114 PolarHBondContact O-N 2.95Å; T112-S115 PolarHBondContact O-N 3.31Å; T112-D116 PolarHBondContact O-N 3.44Å; T112-D116 VanDerWaalsContact O-N 3.14Å; T112-A174 HydrophobicContact CG2-CB 4.49Å
113	Y	95.6	Very high	94.6	Very high	27 Å²	27	37 Å²	37	11%	0.106	19%	0.191	C	C	.	.	H	α-helix	trans	-59.3	-49.4	178.2	176.1	-101.8	0	0	0	112.6	K109 L110 S115 D116 V117 L164 N167 H170 L171	K109-Y113 WeakPolarHBondContact O-CB 3.24Å; K109-Y113 PolarHBondContact O-N 2.84Å; L110-Y113 PolarHBondContact O-N 2.96Å; Y113-S115 PolarHBondContact O-N 3.45Å; Y113-D116 PolarHBondContact O-N 3.25Å; Y113-V117 HydrophobicContact CD1-CG2 4.17Å; Y113-V117 HydrophobicContact CD2-CG2 3.88Å; Y113-V117 HydrophobicContact CE1-CG2 3.9Å; Y113-V117 HydrophobicContact CE2-CG2 3.6Å; Y113-V117 HydrophobicContact CG-CG2 4.17Å; Y113-V117 VanDerWaalsContact O-CB 3.23Å; Y113-V117 WeakPolarHBondContact O-CB 3.49Å; Y113-V117 WeakPolarHBondContact O-CG2 3.45Å; Y113-V117 PolarHBondContact O-N 2.92Å; Y113-L164 HydrophobicContact CE1-CD2 4.06Å; Y113-L164 WeakPolarHBondContact OH-CA 3.16Å; Y113-L164 VanDerWaalsContact OH-CD2 3.23Å; Y113-L164 WeakPolarHBondContact OH-CD2 3.35Å; Y113-L164 PolarHBondContact OH-O 2.95Å; Y113-N167 HydrophobicContact CD2-CB 3.97Å; Y113-N167 WeakPolarHBondContact CD2-O 3.32Å; Y113-N167 HydrophobicContact CE2-CB 3.68Å; Y113-N167 WeakPolarHBondContact CE2-O 3.23Å; Y113-H170 HydrophobicContact CD2-CB 4.29Å; Y113-L171 HydrophobicContact CD1-CD2 4.24Å; Y113-L171 HydrophobicContact CD2-CD1 3.99Å; Y113-L171 HydrophobicContact CD2-CD2 4.11Å; Y113-L171 HydrophobicContact CD2-CG 3.66Å; Y113-L171 HydrophobicContact CE2-CD1 4.02Å; Y113-L171 HydrophobicContact CE2-CG 4.18Å; Y113-L171 HydrophobicContact CG-CD1 4.23Å; Y113-L171 HydrophobicContact CG-CD2 3.72Å; Y113-L171 HydrophobicContact CG-CG 3.83Å
114	L	96.8	Very high	95	Very high	67 Å²	67	29.2 Å²	29.2	35%	0.351	16%	0.162	S	C	.	.	H	α-helix	trans	-63.6	-43.2	-177.1	-75.8	174.2	0	0	0	111.8	I72 V76 L110 T112 S118	I72-L114 HydrophobicContact CG2-CB 4.42Å; V76-L114 HydrophobicContact CG1-CB 4.34Å; V76-L114 HydrophobicContact CG2-CB 4.23Å; V76-L114 HydrophobicContact CG2-CD1 4.43Å; L110-L114 VanDerWaalsContact O-CB 3.26Å; L110-L114 WeakPolarHBondContact O-CB 3.37Å; L110-L114 VanDerWaalsContact O-CG 3.22Å; L110-L114 WeakPolarHBondContact O-CG 3.37Å; L110-L114 PolarHBondContact O-N 3.38Å; T112-L114 PolarHBondContact O-N 2.95Å; L114-S118 WeakPolarHBondContact O-CB 3.09Å; L114-S118 PolarHBondContact O-N 2.84Å; L114-S118 PolarHBondContact O-OG 3.37Å
115	S	94.7	Very high	95.2	Very high	14 Å²	14	27.5 Å²	27.5	10%	0.098	15%	0.15	C	C	.	.	H	α-helix	trans	-58.5	-52.6	176.7	175.3	0	0	0	0	111.5	Q73 L111 T112 Y113 V117 S118 A119	Q73-S115 PolarHBondContact NE2-OG 3.43Å; Q73-S115 PolarHBondContact OE1-O 2.95Å; L111-S115 WeakPolarHBondContact O-CB 3.4Å; L111-S115 PolarHBondContact O-N 3.26Å; T112-S115 PolarHBondContact O-N 3.31Å; Y113-S115 PolarHBondContact O-N 3.45Å; S115-V117 PolarHBondContact O-N 3.29Å; S115-S118 PolarHBondContact O-N 2.97Å; S115-S118 PolarHBondContact O-OG 2.88Å; S115-S118 VanDerWaalsContact O-OG 3.1Å; S115-A119 WeakPolarHBondContact O-CB 3.03Å; S115-A119 PolarHBondContact O-N 3.23Å
116	D	93.3	Very high	95.4	Very high	27 Å²	27	26 Å²	26	14%	0.144	14%	0.139	C	C	.	.	H	α-helix	trans	-70.4	-35.7	-175.2	-67.4	-35.1	0	0	0	111.9	T112 Y113 L120 H170	T112-D116 PolarHBondContact O-N 3.44Å; T112-D116 VanDerWaalsContact O-N 3.14Å; Y113-D116 PolarHBondContact O-N 3.25Å; D116-L120 WeakPolarHBondContact O-CB 3.41Å; D116-L120 PolarHBondContact O-N 3.42Å; D116-H170 IonicContact OD2-CE1 3.23Å; D116-H170 PolarHBondContact OD2-CE1 3.31Å; D116-H170 IonicContact OD2-ND1 2.94Å; D116-H170 PolarHBondContact OD2-ND1 3.49Å; D116-H170 IonicContact OD2-NE2 2.75Å
117	V	96.9	Very high	95.5	Very high	6 Å²	6	21.6 Å²	21.6	4%	0.036	12%	0.115	C	C	.	.	H	α-helix	trans	-63.1	-48.2	172.5	168	0	0	0	0	111.7	Y113 S115 A119 L120 I121 L164 N167	Y113-V117 HydrophobicContact CD1-CG2 4.17Å; Y113-V117 HydrophobicContact CD2-CG2 3.88Å; Y113-V117 HydrophobicContact CE1-CG2 3.9Å; Y113-V117 HydrophobicContact CE2-CG2 3.6Å; Y113-V117 HydrophobicContact CG-CG2 4.17Å; Y113-V117 VanDerWaalsContact O-CB 3.23Å; Y113-V117 WeakPolarHBondContact O-CB 3.49Å; Y113-V117 WeakPolarHBondContact O-CG2 3.45Å; Y113-V117 PolarHBondContact O-N 2.92Å; S115-V117 PolarHBondContact O-N 3.29Å; V117-A119 VanDerWaalsContact C-N 3.34Å; V117-A119 PolarHBondContact O-N 3.39Å; V117-L120 PolarHBondContact O-N 3.37Å; V117-I121 HydrophobicContact CG1-CD1 3.51Å; V117-I121 HydrophobicContact CG1-CG1 4.24Å; V117-I121 WeakPolarHBondContact O-CB 3.36Å; V117-I121 VanDerWaalsContact O-CG1 3.26Å; V117-I121 WeakPolarHBondContact O-CG1 3.12Å; V117-I121 PolarHBondContact O-N 3.02Å; V117-L164 HydrophobicContact CG1-CD2 3.73Å; V117-L164 HydrophobicContact CG1-CG 4.29Å; V117-N167 HydrophobicContact CG2-CB 3.36Å
118	S	97.2	Very high	95.6	Very high	2 Å²	2	21 Å²	21	1%	0.014	11%	0.11	C	C	.	.	H	α-helix	trans	-65.2	-39.3	-178.6	46	0	0	0	0	112	A69 Q73 L114 S115 I121 A122	A69-S118 WeakPolarHBondContact O-CB 3.12Å; Q73-S118 PolarHBondContact OE1-OG 2.86Å; L114-S118 WeakPolarHBondContact O-CB 3.09Å; L114-S118 PolarHBondContact O-N 2.84Å; L114-S118 PolarHBondContact O-OG 3.37Å; S115-S118 PolarHBondContact O-N 2.97Å; S115-S118 PolarHBondContact O-OG 2.88Å; S115-S118 VanDerWaalsContact O-OG 3.1Å; S118-I121 PolarHBondContact O-N 3.26Å; S118-A122 WeakPolarHBondContact O-CB 3.19Å; S118-A122 PolarHBondContact O-N 3.45Å
119	A	94.7	Very high	95.6	Very high	9 Å²	9	21 Å²	21	7%	0.074	11%	0.11	C	C	.	.	H	α-helix	trans	-60.6	-45.9	173.9	0	0	0	0	0	111.7	S115 V117 A122 A123 V207	S115-A119 WeakPolarHBondContact O-CB 3.03Å; S115-A119 PolarHBondContact O-N 3.23Å; V117-A119 VanDerWaalsContact C-N 3.34Å; V117-A119 PolarHBondContact O-N 3.39Å; A119-A122 PolarHBondContact O-N 2.91Å; A119-A123 PolarHBondContact O-N 2.85Å; A119-V207 HydrophobicContact CB-CG1 4.25Å
120	L	95.9	Very high	95.6	Very high	1 Å²	1	18.9 Å²	18.9	1%	0.005	10%	0.101	C	C	.	.	H	α-helix	trans	-63.3	-45.7	177.6	-168.7	71	0	0	0	111.9	D116 V117 A122 A123 F124 C163 N167 V207	D116-L120 WeakPolarHBondContact O-CB 3.41Å; D116-L120 PolarHBondContact O-N 3.42Å; V117-L120 PolarHBondContact O-N 3.37Å; L120-A122 PolarHBondContact O-N 2.98Å; L120-A123 PolarHBondContact O-N 3.49Å; L120-F124 HydrophobicContact CD1-CD2 3.87Å; L120-F124 HydrophobicContact CD1-CE2 3.45Å; L120-F124 VanDerWaalsContact CD1-CE2 3.45Å; L120-F124 HydrophobicContact CD1-CZ 4.49Å; L120-F124 HydrophobicContact CG-CD2 4.02Å; L120-F124 HydrophobicContact CG-CE2 3.97Å; L120-F124 VanDerWaalsContact O-CD2 3.24Å; L120-F124 WeakPolarHBondContact O-CD2 3.43Å; L120-F124 PolarHBondContact O-N 3.46Å; L120-C163 HydrophobicContact CD2-CB 3.91Å; L120-C163 HydrophobicContact CG-CB 4.33Å; L120-N167 VanDerWaalsContact CD2-ND2 3.27Å; L120-N167 WeakPolarHBondContact CD2-ND2 3.5Å; L120-V207 HydrophobicContact CB-CG2 4Å; L120-V207 HydrophobicContact CD1-CB 4.43Å; L120-V207 HydrophobicContact CD1-CG2 3.5Å; L120-V207 HydrophobicContact CG-CG2 4.37Å
121	I	97.7	Very high	95.5	Very high	6 Å²	6	18.2 Å²	18.2	3%	0.031	10%	0.097	C	C	.	.	H	α-helix	trans	-60	-47	177.3	-71.7	170.4	0	0	0	110.7	A69 V117 S118 A123 F124 I125 Y160 C163	A69-I121 HydrophobicContact CB-CB 4.48Å; A69-I121 HydrophobicContact CB-CG2 4.03Å; V117-I121 HydrophobicContact CG1-CD1 3.51Å; V117-I121 HydrophobicContact CG1-CG1 4.24Å; V117-I121 WeakPolarHBondContact O-CB 3.36Å; V117-I121 VanDerWaalsContact O-CG1 3.26Å; V117-I121 WeakPolarHBondContact O-CG1 3.12Å; V117-I121 PolarHBondContact O-N 3.02Å; S118-I121 PolarHBondContact O-N 3.26Å; I121-A123 PolarHBondContact O-N 3.47Å; I121-F124 PolarHBondContact O-N 3Å; I121-I125 HydrophobicContact CG2-CD1 3.57Å; I121-I125 HydrophobicContact CG2-CG1 4.25Å; I121-I125 WeakPolarHBondContact O-CB 3.26Å; I121-I125 VanDerWaalsContact O-CG1 3.27Å; I121-I125 WeakPolarHBondContact O-CG1 3.49Å; I121-I125 PolarHBondContact O-N 3.02Å; I121-Y160 HydrophobicContact CD1-CD1 3.62Å; I121-Y160 HydrophobicContact CD1-CE1 3.71Å; I121-Y160 HydrophobicContact CD1-CG 4.09Å; I121-Y160 HydrophobicContact CG2-CD2 4.05Å; I121-Y160 HydrophobicContact CG2-CE1 4.15Å; I121-Y160 HydrophobicContact CG2-CE2 3.56Å; I121-C163 HydrophobicContact CD1-CB 4.24Å; I121-C163 HydrophobicContact CG1-CB 3.47Å; I121-C163 VanDerWaalsContact CG1-CB 3.47Å
122	A	96.5	Very high	95.3	Very high	7 Å²	7	17.6 Å²	17.6	6%	0.058	9%	0.094	C	C	.	.	H	α-helix	trans	-58.9	-46.8	179.6	0	0	0	0	0	111.5	A69 S118 A119 L120 F124 I125 L126	A69-A122 HydrophobicContact CB-CB 4.03Å; S118-A122 WeakPolarHBondContact O-CB 3.19Å; S118-A122 PolarHBondContact O-N 3.45Å; A119-A122 PolarHBondContact O-N 2.91Å; L120-A122 PolarHBondContact O-N 2.98Å; A122-F124 PolarHBondContact O-N 3.34Å; A122-I125 PolarHBondContact O-N 3.38Å; A122-L126 WeakPolarHBondContact O-CB 3.35Å; A122-L126 PolarHBondContact O-N 3Å
123	A	95.4	Very high	95.2	Very high	2 Å²	2	16.6 Å²	16.6	2%	0.017	9%	0.086	C	C	.	.	H	α-helix	trans	-63.6	-43	179.4	0	0	0	0	0	112.3	A119 L120 I121 L126 M127 V207 P211	A119-A123 PolarHBondContact O-N 2.85Å; L120-A123 PolarHBondContact O-N 3.49Å; I121-A123 PolarHBondContact O-N 3.47Å; A123-L126 PolarHBondContact O-N 3.29Å; A123-M127 WeakPolarHBondContact O-CB 3.18Å; A123-M127 PolarHBondContact O-N 3.25Å; A123-V207 HydrophobicContact CB-CG1 4.34Å; A123-P211 HydrophobicContact CB-CB 4.07Å; A123-P211 HydrophobicContact CB-CG 3.81Å
124	F	96.8	Very high	94.9	Very high	38 Å²	38	16.1 Å²	16.1	17%	0.167	9%	0.087	C	C	.	.	H	α-helix	trans	-69.1	-37.2	178	-86.9	-109.6	0	0	0	112.8	L120 I121 A122 M127 L128 I159 G206 L210	L120-F124 HydrophobicContact CD1-CD2 3.87Å; L120-F124 HydrophobicContact CD1-CE2 3.45Å; L120-F124 VanDerWaalsContact CD1-CE2 3.45Å; L120-F124 HydrophobicContact CD1-CZ 4.49Å; L120-F124 HydrophobicContact CG-CD2 4.02Å; L120-F124 HydrophobicContact CG-CE2 3.97Å; L120-F124 VanDerWaalsContact O-CD2 3.24Å; L120-F124 WeakPolarHBondContact O-CD2 3.43Å; L120-F124 PolarHBondContact O-N 3.46Å; I121-F124 PolarHBondContact O-N 3Å; A122-F124 PolarHBondContact O-N 3.34Å; F124-M127 HydrophobicContact CD1-CE 3.67Å; F124-M127 HydrophobicContact CE1-CE 4.02Å; F124-M127 HydrophobicContact CG-CE 4.17Å; F124-M127 PolarHBondContact O-N 3.44Å; F124-L128 WeakPolarHBondContact O-CB 3.28Å; F124-L128 PolarHBondContact O-N 3.34Å; F124-I159 HydrophobicContact CB-CD1 4.36Å; F124-I159 HydrophobicContact CB-CG1 4.5Å; F124-I159 HydrophobicContact CB-CG2 3.73Å; F124-G206 VanDerWaalsContact CE2-O 3.23Å; F124-G206 WeakPolarHBondContact CE2-O 3.23Å; F124-L210 HydrophobicContact CZ-CD2 4.43Å
125	I	97.1	Very high	94.5	Very high	0 Å²	0	15.6 Å²	15.6	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-65.5	-43.4	173.8	-69	173.3	0	0	0	110.3	Y62 W65 M66 I121 A122 M127 L128 F129 I159 Y160	Y62-I125 HydrophobicContact CD1-CG2 4.34Å; W65-I125 HydrophobicContact CB-CD1 3.95Å; M66-I125 HydrophobicContact CB-CG2 4.13Å; M66-I125 HydrophobicContact CE-CG2 3.86Å; I121-I125 HydrophobicContact CG2-CD1 3.57Å; I121-I125 HydrophobicContact CG2-CG1 4.25Å; I121-I125 WeakPolarHBondContact O-CB 3.26Å; I121-I125 VanDerWaalsContact O-CG1 3.27Å; I121-I125 WeakPolarHBondContact O-CG1 3.49Å; I121-I125 PolarHBondContact O-N 3.02Å; A122-I125 PolarHBondContact O-N 3.38Å; I125-M127 VanDerWaalsContact C-N 3.32Å; I125-M127 PolarHBondContact O-N 2.94Å; I125-L128 PolarHBondContact O-N 3.47Å; I125-F129 VanDerWaalsContact O-CB 3.25Å; I125-F129 WeakPolarHBondContact O-CB 3.31Å; I125-F129 PolarHBondContact O-N 3.5Å; I125-I159 HydrophobicContact CG1-CG2 4.31Å; I125-Y160 HydrophobicContact CD1-CE2 3.87Å
126	L	95.9	Very high	93.9	Very high	8 Å²	8	15.4 Å²	15.4	4%	0.042	9%	0.086	C	C	.	.	H	α-helix	trans	-62.6	-40.3	177.6	-177.2	61.7	0	0	0	111.9	M66 A122 A123 F129 S130 I215 I256 F260	M66-L126 HydrophobicContact CE-CB 3.78Å; M66-L126 HydrophobicContact CE-CD1 3.8Å; M66-L126 HydrophobicContact CE-CG 4.4Å; M66-L126 HydrophobicContact SD-CD1 4.47Å; A122-L126 WeakPolarHBondContact O-CB 3.35Å; A122-L126 PolarHBondContact O-N 3Å; A123-L126 PolarHBondContact O-N 3.29Å; L126-F129 WeakPolarHBondContact O-CB 3.26Å; L126-F129 PolarHBondContact O-N 2.92Å; L126-S130 PolarHBondContact O-N 3.09Å; L126-S130 PolarHBondContact O-OG 3.22Å; L126-I215 HydrophobicContact CB-CD1 4.31Å; L126-I215 HydrophobicContact CD2-CD1 3.67Å; L126-I215 HydrophobicContact CG-CD1 3.71Å; L126-I256 HydrophobicContact CD1-CG2 3.96Å; L126-F260 HydrophobicContact CD2-CB 3.79Å; L126-F260 HydrophobicContact CD2-CD1 3.77Å; L126-F260 HydrophobicContact CD2-CD2 3.83Å; L126-F260 HydrophobicContact CD2-CE1 4.31Å; L126-F260 HydrophobicContact CD2-CE2 4.36Å; L126-F260 HydrophobicContact CD2-CG 3.5Å; L126-F260 VanDerWaalsContact CD2-CG 3.5Å
127	M	95.4	Very high	93.4	Very high	22 Å²	22	15.2 Å²	15.2	11%	0.108	9%	0.085	C	C	.	.	H	α-helix	trans	-62.8	-48.6	173.1	179.9	-176.3	70.6	0	0	111.9	A123 F124 I125 F129 S130 I131 L214	A123-M127 WeakPolarHBondContact O-CB 3.18Å; A123-M127 PolarHBondContact O-N 3.25Å; F124-M127 HydrophobicContact CD1-CE 3.67Å; F124-M127 HydrophobicContact CE1-CE 4.02Å; F124-M127 HydrophobicContact CG-CE 4.17Å; F124-M127 PolarHBondContact O-N 3.44Å; I125-M127 VanDerWaalsContact C-N 3.32Å; I125-M127 PolarHBondContact O-N 2.94Å; M127-F129 VanDerWaalsContact C-N 3.28Å; M127-F129 PolarHBondContact O-N 3.42Å; M127-S130 WeakPolarHBondContact O-CB 3.3Å; M127-S130 PolarHBondContact O-N 3.43Å; M127-S130 VanDerWaalsContact O-N 3.16Å; M127-I131 HydrophobicContact CG-CD1 4.34Å; M127-I131 WeakPolarHBondContact O-CG1 3.39Å; M127-I131 PolarHBondContact O-N 3.27Å; M127-L214 HydrophobicContact CG-CB 4.1Å; M127-L214 HydrophobicContact CG-CD1 4.06Å; M127-L214 HydrophobicContact SD-CB 4.26Å; M127-L214 HydrophobicContact SD-CD1 3.3Å; M127-L214 WeakPolarHBondContact SD-CD1 3.45Å; M127-L214 HydrophobicContact SD-CG 4.39Å
128	L	95.4	Very high	92.8	Very high	23 Å²	23	19.9 Å²	19.9	12%	0.12	10%	0.103	C	C	.	.	H	α-helix	trans	-60.4	-40	176.2	177.4	63.5	0	0	0	111.4	Y62 F124 I125 S130 I131 D132 F155 I159	Y62-L128 HydrophobicContact CE1-CD2 3.6Å; Y62-L128 HydrophobicContact CE1-CG 3.97Å; F124-L128 WeakPolarHBondContact O-CB 3.28Å; F124-L128 PolarHBondContact O-N 3.34Å; I125-L128 PolarHBondContact O-N 3.47Å; L128-S130 VanDerWaalsContact C-N 3.32Å; L128-S130 PolarHBondContact O-N 3.27Å; L128-I131 PolarHBondContact O-N 2.98Å; L128-D132 WeakPolarHBondContact O-CB 3.41Å; L128-D132 PolarHBondContact O-N 3.26Å; L128-F155 HydrophobicContact CD2-CB 3.67Å; L128-I159 HydrophobicContact CB-CD1 4.03Å; L128-I159 HydrophobicContact CD2-CD1 3.58Å; L128-I159 HydrophobicContact CG-CD1 4.4Å
129	F	94.3	Very high	91.9	Very high	2 Å²	2	22.3 Å²	22.3	1%	0.009	12%	0.119	C	C	.	.	H	α-helix	trans	-61.9	-42.5	176.3	-165.4	-179.2	0	0	0	111	F59 Y62 M66 I125 L126 M127 I131 D132 R133 H253	F59-F129 AromaticContact CD2-CE2 3.69Å; F59-F129 HydrophobicContact CD2-CE2 3.69Å; F59-F129 AromaticContact CD2-CZ 3.32Å; F59-F129 HydrophobicContact CD2-CZ 3.32Å; F59-F129 HydrophobicContact CE2-CE1 4.37Å; F59-F129 HydrophobicContact CE2-CE2 4.16Å; F59-F129 AromaticContact CE2-CZ 3.43Å; F59-F129 HydrophobicContact CE2-CZ 3.43Å; F59-F129 VanDerWaalsContact CE2-CZ 3.43Å; F59-F129 HydrophobicContact CG-CE2 4.37Å; F59-F129 AromaticContact CG-CZ 3.94Å; F59-F129 HydrophobicContact CG-CZ 3.94Å; F59-F129 HydrophobicContact CZ-CZ 4.15Å; Y62-F129 HydrophobicContact CD2-CB 4.41Å; Y62-F129 AromaticContact CD2-CD2 3.68Å; Y62-F129 HydrophobicContact CD2-CD2 3.68Å; Y62-F129 HydrophobicContact CD2-CE2 4.06Å; Y62-F129 HydrophobicContact CD2-CG 4.07Å; Y62-F129 HydrophobicContact CE2-CD2 4.37Å; Y62-F129 HydrophobicContact CG-CB 4.39Å; Y62-F129 HydrophobicContact CG-CD2 4.29Å; Y62-F129 HydrophobicContact CG-CG 4.24Å; M66-F129 HydrophobicContact CE-CD1 4.02Å; I125-F129 VanDerWaalsContact O-CB 3.25Å; I125-F129 WeakPolarHBondContact O-CB 3.31Å; I125-F129 PolarHBondContact O-N 3.5Å; L126-F129 WeakPolarHBondContact O-CB 3.26Å; L126-F129 PolarHBondContact O-N 2.92Å; M127-F129 VanDerWaalsContact C-N 3.28Å; M127-F129 PolarHBondContact O-N 3.42Å; F129-I131 PolarHBondContact O-N 3.46Å; F129-D132 PolarHBondContact O-N 3.46Å; F129-R133 HydrophobicContact CD2-CG 3.99Å; F129-R133 HydrophobicContact CE2-CG 4.09Å; F129-R133 VanDerWaalsContact O-CG 3.32Å; F129-R133 WeakPolarHBondContact O-CG 3.33Å; F129-R133 PolarHBondContact O-N 2.81Å; F129-H253 AromaticContact CD1-CD2 3.69Å; F129-H253 AromaticContact CD2-CD2 3.85Å; F129-H253 AromaticContact CE1-CD2 3.99Å; F129-H253 AromaticContact CG-CD2 3.62Å; F129-H253 AromaticContact CG-NE2 3.96Å
130	S	94	Very high	90.4	Very high	0 Å²	0	27 Å²	27	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-61.2	-45	175.9	-60.3	0	0	0	0	112.2	L126 M127 L128 R133 V134 H253	L126-S130 PolarHBondContact O-N 3.09Å; L126-S130 PolarHBondContact O-OG 3.22Å; M127-S130 WeakPolarHBondContact O-CB 3.3Å; M127-S130 PolarHBondContact O-N 3.43Å; M127-S130 VanDerWaalsContact O-N 3.16Å; L128-S130 VanDerWaalsContact C-N 3.32Å; L128-S130 PolarHBondContact O-N 3.27Å; S130-R133 PolarHBondContact O-N 2.89Å; S130-V134 PolarHBondContact O-N 3.37Å; S130-H253 VanDerWaalsContact CA-CE1 3.48Å; S130-H253 WeakPolarHBondContact CA-CE1 3.38Å; S130-H253 VanDerWaalsContact CA-NE2 3.34Å; S130-H253 WeakPolarHBondContact CA-NE2 3.49Å; S130-H253 PolarHBondContact N-NE2 3.31Å; S130-H253 PolarHBondContact OG-CE1 3.05Å; S130-H253 PolarHBondContact OG-NE2 3.25Å; S130-H253 VanDerWaalsContact OG-NE2 3.15Å
131	I	93.2	Very high	88.7	Confident	60 Å²	60	29.3 Å²	29.3	31%	0.308	16%	0.157	S	C	.	.	H	α-helix	trans	-61.1	-47.4	175	-66	165	0	0	0	110	M127 L128 F129 R133 V134 C135 M218	M127-I131 HydrophobicContact CG-CD1 4.34Å; M127-I131 WeakPolarHBondContact O-CG1 3.39Å; M127-I131 PolarHBondContact O-N 3.27Å; L128-I131 PolarHBondContact O-N 2.98Å; F129-I131 PolarHBondContact O-N 3.46Å; I131-R133 VanDerWaalsContact C-N 3.28Å; I131-R133 PolarHBondContact O-N 3.43Å; I131-V134 PolarHBondContact O-N 2.86Å; I131-C135 PolarHBondContact O-N 3.19Å; I131-C135 PolarHBondContact O-SG 3.48Å; I131-C135 VanDerWaalsContact O-SG 3.41Å; I131-M218 HydrophobicContact CG1-CE 3.89Å; I131-M218 HydrophobicContact CG1-SD 4.37Å
132	D	91.5	Very high	86.7	Confident	15 Å²	15	36.7 Å²	36.7	8%	0.08	19%	0.191	C	C	.	.	H	α-helix	trans	-60.7	-36.5	178.8	-178.5	73.4	0	0	0	112.5	R58 Y62 L128 F129 C135 S136	R58-D132 IonicContact CZ-OD1 3.88Å; R58-D132 IonicContact CZ-OD2 3.12Å; R58-D132 IonicContact NE-OD1 3.79Å; R58-D132 IonicContact NH1-OD1 3.22Å; R58-D132 PolarHBondContact NH1-OD1 2.85Å; R58-D132 IonicContact NH2-OD1 3.92Å; Y62-D132 HydrophobicContact CE2-CB 3.91Å; L128-D132 WeakPolarHBondContact O-CB 3.41Å; L128-D132 PolarHBondContact O-N 3.26Å; F129-D132 PolarHBondContact O-N 3.46Å; D132-C135 WeakPolarHBondContact O-CA 3.27Å; D132-S136 WeakPolarHBondContact O-CB 3.47Å; D132-S136 PolarHBondContact O-N 3.39Å; D132-S136 PolarHBondContact O-OG 2.94Å
133	R	89.9	Confident	84.6	Confident	12 Å²	12	44 Å²	44	5%	0.045	23%	0.228	C	C	.	.	H	α-helix	trans	-66.4	-46.8	175.1	-70.5	-53.6	88.1	179.3	4.5	111.8	F129 S130 I131 C135 S136 I137 I222 H253	F129-R133 HydrophobicContact CD2-CG 3.99Å; F129-R133 HydrophobicContact CE2-CG 4.09Å; F129-R133 VanDerWaalsContact O-CG 3.32Å; F129-R133 WeakPolarHBondContact O-CG 3.33Å; F129-R133 PolarHBondContact O-N 2.81Å; S130-R133 PolarHBondContact O-N 2.89Å; I131-R133 VanDerWaalsContact C-N 3.28Å; I131-R133 PolarHBondContact O-N 3.43Å; R133-C135 VanDerWaalsContact C-N 3.35Å; R133-S136 PolarHBondContact O-N 2.88Å; R133-I137 WeakPolarHBondContact O-CB 3.37Å; R133-I137 WeakPolarHBondContact O-CD1 3.32Å; R133-I137 WeakPolarHBondContact O-CG1 3.33Å; R133-I137 PolarHBondContact O-N 3.41Å; R133-I222 HydrophobicContact CB-CD1 3.95Å; R133-H253 HydrophobicContact CG-CB 4.31Å
134	V	90.1	Very high	82.9	Confident	18 Å²	18	47 Å²	47	11%	0.109	24%	0.242	C	C	.	.	H	α-helix	trans	-60.4	-48	173.7	173.1	0	0	0	0	110.2	S130 I131 S136 I137 Y138 M218 L221 I222	S130-V134 PolarHBondContact O-N 3.37Å; I131-V134 PolarHBondContact O-N 2.86Å; V134-S136 VanDerWaalsContact C-N 3.33Å; V134-S136 PolarHBondContact O-N 3.5Å; V134-I137 PolarHBondContact O-N 2.92Å; V134-I137 VanDerWaalsContact O-N 3.15Å; V134-Y138 HydrophobicContact CG1-CD2 3.75Å; V134-Y138 HydrophobicContact CG1-CE2 3.96Å; V134-Y138 WeakPolarHBondContact O-CD2 3.38Å; V134-Y138 PolarHBondContact O-N 3.44Å; V134-M218 HydrophobicContact CB-SD 3.93Å; V134-M218 HydrophobicContact CG1-SD 4.25Å; V134-M218 HydrophobicContact CG2-CB 4.04Å; V134-M218 HydrophobicContact CG2-CG 4.37Å; V134-M218 HydrophobicContact CG2-SD 3.55Å; V134-M218 VanDerWaalsContact CG2-SD 3.55Å; V134-L221 HydrophobicContact CG1-CD1 4.34Å; V134-L221 HydrophobicContact CG2-CB 4.26Å; V134-I222 HydrophobicContact CG2-CD1 4.11Å; V134-I222 HydrophobicContact CG2-CG1 3.62Å
135	C	87.6	Confident	81.1	Confident	56 Å²	56	49.5 Å²	49.5	38%	0.378	25%	0.254	S	S	.	.	H	α-helix	trans	-31.9	-63.9	164	70.3	0	0	0	0	113.6	I131 D132 R133 C139	I131-C135 PolarHBondContact O-N 3.19Å; I131-C135 PolarHBondContact O-SG 3.48Å; I131-C135 VanDerWaalsContact O-SG 3.41Å; D132-C135 WeakPolarHBondContact O-CA 3.27Å; R133-C135 VanDerWaalsContact C-N 3.35Å; C135-C139 WeakPolarHBondContact O-CB 3.42Å; C135-C139 PolarHBondContact O-N 3Å; C135-C139 VanDerWaalsContact O-N 3.1Å
136	S	83.5	Confident	79.3	Confident	10 Å²	10	56 Å²	56	7%	0.07	29%	0.287	C	S	.	.	H	α-helix	trans	-72.2	-30.5	-172.2	-56.3	0	0	0	0	112.8	R58 D132 R133 V134 F474	R58-S136 PolarHBondContact NH2-OG 3.25Å; D132-S136 WeakPolarHBondContact O-CB 3.47Å; D132-S136 PolarHBondContact O-N 3.39Å; D132-S136 PolarHBondContact O-OG 2.94Å; R133-S136 PolarHBondContact O-N 2.88Å; V134-S136 VanDerWaalsContact C-N 3.33Å; V134-S136 PolarHBondContact O-N 3.5Å; S136-F474 VanDerWaalsContact O-CE1 3.27Å; S136-F474 WeakPolarHBondContact O-CE1 3.11Å; S136-F474 VanDerWaalsContact O-CZ 3.27Å; S136-F474 WeakPolarHBondContact O-CZ 3.35Å
137	I	83.5	Confident	77.6	Confident	22 Å²	22	61.4 Å²	61.4	11%	0.113	32%	0.315	C	S	.	.	H	α-helix	trans	-80.1	-34.8	-178.2	-71.7	168.4	0	0	0	111.7	R133 V134 I222 K225 V250	R133-I137 WeakPolarHBondContact O-CB 3.37Å; R133-I137 WeakPolarHBondContact O-CD1 3.32Å; R133-I137 WeakPolarHBondContact O-CG1 3.33Å; R133-I137 PolarHBondContact O-N 3.41Å; V134-I137 PolarHBondContact O-N 2.92Å; V134-I137 VanDerWaalsContact O-N 3.15Å; I137-I222 HydrophobicContact CD1-CG1 4.17Å; I137-I222 HydrophobicContact CD1-CG2 4.08Å; I137-K225 HydrophobicContact CG2-CB 3.9Å; I137-K225 HydrophobicContact CG2-CD 4.39Å; I137-K225 HydrophobicContact CG2-CG 3.18Å; I137-V250 HydrophobicContact CD1-CG1 4Å; I137-V250 HydrophobicContact CD1-CG2 3.96Å; I137-V250 HydrophobicContact CG1-CG2 4.4Å
138	Y	83.1	Confident	76.9	Confident	104 Å²	104	61.4 Å²	61.4	41%	0.408	32%	0.315	S	S	.	.	H	α-helix	trans	-88.7	-34.2	-177.4	-80.8	-97.2	0	0	0	113.2	V134 L221 K225	V134-Y138 HydrophobicContact CG1-CD2 3.75Å; V134-Y138 HydrophobicContact CG1-CE2 3.96Å; V134-Y138 WeakPolarHBondContact O-CD2 3.38Å; V134-Y138 PolarHBondContact O-N 3.44Å; Y138-L221 HydrophobicContact CE2-CB 4.45Å; Y138-K225 HydrophobicContact CE2-CB 4.01Å; Y138-K225 HydrophobicContact CE2-CG 4.13Å
139	C	77.7	Confident	76.5	Confident	54 Å²	54	61.8 Å²	61.8	37%	0.365	32%	0.317	S	S	.	.	S	Bend	trans	-92.1	118.8	176.9	-58.6	0	0	0	0	110.1	C135 K141	C135-C139 WeakPolarHBondContact O-CB 3.42Å; C135-C139 PolarHBondContact O-N 3Å; C135-C139 VanDerWaalsContact O-N 3.1Å; C139-K141 HydrophobicContact CB-CD 4.29Å; C139-K141 HydrophobicContact CB-CG 3.9Å; C139-K141 WeakPolarHBondContact O-CG 3.26Å; C139-K141 PolarHBondContact O-N 3.35Å
140	T	65.1	Low	76.2	Confident	108 Å²	108	70.9 Å²	70.9	66%	0.663	35%	0.351	S	S	*	.			trans	-81	95.2	171.1	40.8	0	0	0	0	109.7	Q142	T140-Q142 PolarHBondContact O-N 2.68Å
141	K	58.2	Low	76.1	Confident	49 Å²	49	73.9 Å²	73.9	21%	0.213	37%	0.367	C	S	.	.			trans	-94.4	92.5	-166.3	-55.3	-171.2	169.7	-145.4	0	113.3	C139 E144 H148	C139-K141 HydrophobicContact CB-CD 4.29Å; C139-K141 HydrophobicContact CB-CG 3.9Å; C139-K141 WeakPolarHBondContact O-CG 3.26Å; C139-K141 PolarHBondContact O-N 3.35Å; K141-E144 HydrophobicContact CB-CB 4.21Å; K141-E144 HydrophobicContact CB-CG 4.16Å; K141-E144 HydrophobicContact CD-CB 3.89Å; K141-E144 HydrophobicContact CD-CG 3.94Å; K141-E144 WeakPolarHBondContact CD-OE1 3.49Å; K141-E144 VanDerWaalsContact CE-CD 3.46Å; K141-E144 WeakPolarHBondContact CE-OE1 3.42Å; K141-E144 WeakPolarHBondContact CE-OE2 3.46Å; K141-E144 HydrophobicContact CG-CB 4.45Å; K141-E144 HydrophobicContact CG-CG 4.2Å; K141-E144 WeakPolarHBondContact CG-OE1 3.36Å; K141-E144 IonicContact NZ-OE1 3.53Å; K141-E144 PolarHBondContact NZ-OE1 3.42Å; K141-E144 VanDerWaalsContact NZ-OE1 3.12Å; K141-E144 IonicContact NZ-OE2 2.97Å; K141-E144 PolarHBondContact NZ-OE2 2.96Å; K141-H148 WeakPolarHBondContact CD-NE2 3.23Å; K141-H148 PolarHBondContact NZ-CE1 2.87Å; K141-H148 VanDerWaalsContact NZ-CE1 3.29Å; K141-H148 PolarHBondContact NZ-NE2 3.24Å
142	Q	57.4	Low	76	Confident	160 Å²	160	71.1 Å²	71.1	75%	0.748	35%	0.353	S	S	*	.	S	Bend	trans	-76.1	-7.3	164.2	-79.1	-178.6	-53.6	0	0	113.2	T140	T140-Q142 PolarHBondContact O-N 2.68Å
143	I	51.6	Low	76.2	Confident	160 Å²	160	75.5 Å²	75.5	82%	0.821	37%	0.371	S	S	*	.	S	Bend	trans	-124.5	-10.8	-165.1	-66.1	177.7	0	0	0	114.7
144	E	59.1	Low	76.4	Confident	66 Å²	66	79.7 Å²	79.7	31%	0.308	39%	0.394	S	S	.	.			trans	-109.5	4.4	-157	-51.4	-176.8	-120.5	0	0	117.5	K141 I146 H148	K141-E144 HydrophobicContact CB-CB 4.21Å; K141-E144 HydrophobicContact CB-CG 4.16Å; K141-E144 HydrophobicContact CD-CB 3.89Å; K141-E144 HydrophobicContact CD-CG 3.94Å; K141-E144 WeakPolarHBondContact CD-OE1 3.49Å; K141-E144 VanDerWaalsContact CE-CD 3.46Å; K141-E144 WeakPolarHBondContact CE-OE1 3.42Å; K141-E144 WeakPolarHBondContact CE-OE2 3.46Å; K141-E144 HydrophobicContact CG-CB 4.45Å; K141-E144 HydrophobicContact CG-CG 4.2Å; K141-E144 WeakPolarHBondContact CG-OE1 3.36Å; K141-E144 IonicContact NZ-OE1 3.53Å; K141-E144 PolarHBondContact NZ-OE1 3.42Å; K141-E144 VanDerWaalsContact NZ-OE1 3.12Å; K141-E144 IonicContact NZ-OE2 2.97Å; K141-E144 PolarHBondContact NZ-OE2 2.96Å; E144-I146 PolarHBondContact O-N 2.94Å; E144-H148 WeakPolarHBondContact CB-CD2 3.48Å; E144-H148 WeakPolarHBondContact CB-NE2 3.43Å; E144-H148 VanDerWaalsContact CD-NE2 3.32Å; E144-H148 WeakPolarHBondContact O-CB 3.46Å; E144-H148 PolarHBondContact O-CD2 2.85Å; E144-H148 PolarHBondContact O-N 3.21Å; E144-H148 IonicContact OE2-CD2 2.68Å; E144-H148 IonicContact OE2-CE1 2.72Å; E144-H148 PolarHBondContact OE2-CE1 3.45Å; E144-H148 IonicContact OE2-ND1 3.9Å; E144-H148 IonicContact OE2-NE2 2.71Å; E144-H148 PolarHBondContact OE2-NE2 2.92Å
145	Q	60.5	Low	76.7	Confident	91 Å²	91	83.6 Å²	83.6	43%	0.425	41%	0.41	S	S	.	.	H	α-helix	trans	-66.2	-38.3	-165.2	-69.2	-172.6	-10.3	0	0	116	Y475	Q145-Y475 PolarHBondContact NE2-O 3.21Å; Q145-Y475 PolarHBondContact OE1-O 3.41Å
146	I	58.8	Low	77.1	Confident	137 Å²	137	81 Å²	81	70%	0.703	39%	0.392	S	S	*	.	H	α-helix	trans	-84.3	-46.8	-175.5	-60.8	174	0	0	0	111.5	E144 H148 L149	E144-I146 PolarHBondContact O-N 2.94Å; I146-H148 PolarHBondContact O-N 2.96Å; I146-L149 PolarHBondContact O-N 2.77Å
147	L	60.6	Low	77.8	Confident	120 Å²	120	87 Å²	87	63%	0.628	42%	0.417	S	S	*	.	H	α-helix	trans	-59.5	-35.2	179.9	-170.5	69.2	0	0	0	110.7	L149 I151	L147-L149 PolarHBondContact O-N 3.42Å; L147-I151 HydrophobicContact CD2-CD1 4.22Å; L147-I151 HydrophobicContact CG-CD1 3.81Å; L147-I151 VanDerWaalsContact O-CG1 3.26Å; L147-I151 WeakPolarHBondContact O-CG1 3.36Å; L147-I151 PolarHBondContact O-N 3.47Å; L147-I151 VanDerWaalsContact O-N 3.15Å
148	H	79.7	Confident	78.4	Confident	23 Å²	23	89.4 Å²	89.4	11%	0.106	43%	0.43	C	S	.	.	H	α-helix	trans	-69.7	-28.6	180	-76.7	-32.1	0	0	0	116.4	K141 E144 I146 A152	K141-H148 WeakPolarHBondContact CD-NE2 3.23Å; K141-H148 PolarHBondContact NZ-CE1 2.87Å; K141-H148 VanDerWaalsContact NZ-CE1 3.29Å; K141-H148 PolarHBondContact NZ-NE2 3.24Å; E144-H148 WeakPolarHBondContact CB-CD2 3.48Å; E144-H148 WeakPolarHBondContact CB-NE2 3.43Å; E144-H148 VanDerWaalsContact CD-NE2 3.32Å; E144-H148 WeakPolarHBondContact O-CB 3.46Å; E144-H148 PolarHBondContact O-CD2 2.85Å; E144-H148 PolarHBondContact O-N 3.21Å; E144-H148 IonicContact OE2-CD2 2.68Å; E144-H148 IonicContact OE2-CE1 2.72Å; E144-H148 PolarHBondContact OE2-CE1 3.45Å; E144-H148 IonicContact OE2-ND1 3.9Å; E144-H148 IonicContact OE2-NE2 2.71Å; E144-H148 PolarHBondContact OE2-NE2 2.92Å; I146-H148 PolarHBondContact O-N 2.96Å; H148-A152 VanDerWaalsContact O-CB 3.3Å; H148-A152 WeakPolarHBondContact O-CB 3.13Å; H148-A152 PolarHBondContact O-N 2.81Å
149	L	87.1	Confident	79.1	Confident	31 Å²	31	85.4 Å²	85.4	16%	0.162	42%	0.415	C	S	.	.	H	α-helix	trans	-71.3	-40.4	179.2	-170.6	68	0	0	0	110.6	R58 L61 I146 L147 A152 K153	R58-L149 HydrophobicContact CG-CD1 4.17Å; L61-L149 HydrophobicContact CD2-CD1 4.33Å; I146-L149 PolarHBondContact O-N 2.77Å; L147-L149 PolarHBondContact O-N 3.42Å; L149-A152 PolarHBondContact O-N 3.49Å; L149-K153 WeakPolarHBondContact O-CG 3.03Å; L149-K153 PolarHBondContact O-N 3.37Å
150	R	88.8	Confident	80	Confident	193 Å²	193	84.6 Å²	84.6	73%	0.728	41%	0.405	S	S	*	.	H	α-helix	trans	-63.2	-43.6	173.9	-68.2	-174	-175	169.4	1.8	111.1	K153 L154	R150-K153 PolarHBondContact O-N 2.98Å; R150-L154 WeakPolarHBondContact O-CB 3.25Å; R150-L154 PolarHBondContact O-N 3.48Å
151	I	90.6	Very high	81.6	Confident	62 Å²	62	81.4 Å²	81.4	32%	0.318	39%	0.387	S	S	.	.	H	α-helix	trans	-62.1	-43.2	176	-69.4	169.9	0	0	0	111.2	L147 K153 L154 F155	L147-I151 HydrophobicContact CD2-CD1 4.22Å; L147-I151 HydrophobicContact CG-CD1 3.81Å; L147-I151 VanDerWaalsContact O-CG1 3.26Å; L147-I151 WeakPolarHBondContact O-CG1 3.36Å; L147-I151 PolarHBondContact O-N 3.47Å; L147-I151 VanDerWaalsContact O-N 3.15Å; I151-K153 PolarHBondContact O-N 3Å; I151-L154 WeakPolarHBondContact O-CB 3.06Å; I151-L154 PolarHBondContact O-N 2.96Å; I151-F155 HydrophobicContact CG2-CD2 3.49Å; I151-F155 VanDerWaalsContact CG2-CD2 3.49Å; I151-F155 HydrophobicContact CG2-CE2 3.26Å; I151-F155 HydrophobicContact CG2-CZ 4.37Å; I151-F155 VanDerWaalsContact O-CD2 3.27Å; I151-F155 WeakPolarHBondContact O-CD2 3.27Å; I151-F155 PolarHBondContact O-N 3.14Å
152	A	92.3	Very high	83.5	Confident	2 Å²	2	83.1 Å²	83.1	2%	0.017	40%	0.397	C	S	.	.	H	α-helix	trans	-62.3	-43.6	176.9	0	0	0	0	0	111.8	R58 L61 H148 L149 L154 F155 I156	R58-A152 HydrophobicContact CG-CB 4.04Å; L61-A152 HydrophobicContact CD2-CB 4.13Å; H148-A152 VanDerWaalsContact O-CB 3.3Å; H148-A152 WeakPolarHBondContact O-CB 3.13Å; H148-A152 PolarHBondContact O-N 2.81Å; L149-A152 PolarHBondContact O-N 3.49Å; A152-L154 VanDerWaalsContact C-N 3.33Å; A152-L154 PolarHBondContact O-N 2.82Å; A152-F155 PolarHBondContact O-N 3.39Å; A152-I156 VanDerWaalsContact O-CG1 3.28Å; A152-I156 WeakPolarHBondContact O-CG1 3.49Å; A152-I156 PolarHBondContact O-N 3.49Å
153	K	94.3	Very high	85.4	Confident	108 Å²	108	75.6 Å²	75.6	47%	0.47	36%	0.362	S	S	.	.	H	α-helix	trans	-59.2	-43.4	173.4	-72.5	178	-179.1	-176.4	0	111.7	L61 L149 R150 I151 I156 F157	L61-K153 HydrophobicContact CD1-CG 4.31Å; L61-K153 HydrophobicContact CD2-CB 4.4Å; L61-K153 HydrophobicContact CD2-CG 3.49Å; L61-K153 VanDerWaalsContact CD2-CG 3.49Å; L149-K153 WeakPolarHBondContact O-CG 3.03Å; L149-K153 PolarHBondContact O-N 3.37Å; R150-K153 PolarHBondContact O-N 2.98Å; I151-K153 PolarHBondContact O-N 3Å; K153-I156 PolarHBondContact O-N 2.87Å; K153-F157 WeakPolarHBondContact O-CB 3.38Å; K153-F157 PolarHBondContact O-N 3.4Å
154	L	95.2	Very high	87.5	Confident	99 Å²	99	71.1 Å²	71.1	52%	0.518	34%	0.339	S	S	.	.	H	α-helix	trans	-61.6	-47.9	176.9	-178.8	67.5	0	0	0	111.5	R150 I151 A152 I156 F157 L158	R150-L154 WeakPolarHBondContact O-CB 3.25Å; R150-L154 PolarHBondContact O-N 3.48Å; I151-L154 WeakPolarHBondContact O-CB 3.06Å; I151-L154 PolarHBondContact O-N 2.96Å; A152-L154 VanDerWaalsContact C-N 3.33Å; A152-L154 PolarHBondContact O-N 2.82Å; L154-I156 PolarHBondContact O-N 3.35Å; L154-F157 PolarHBondContact O-N 2.92Å; L154-L158 HydrophobicContact CD1-CD1 4.42Å; L154-L158 HydrophobicContact CD1-CG 4.39Å; L154-L158 HydrophobicContact CG-CD1 4.08Å; L154-L158 HydrophobicContact CG-CG 4.43Å; L154-L158 WeakPolarHBondContact O-CB 3.04Å; L154-L158 VanDerWaalsContact O-CG 3.29Å; L154-L158 WeakPolarHBondContact O-CG 3.32Å; L154-L158 PolarHBondContact O-N 2.76Å
155	F	95.5	Very high	89.3	Confident	100 Å²	100	73.3 Å²	73.3	44%	0.439	35%	0.353	S	S	.	.	H	α-helix	trans	-62.6	-41.9	178.6	-80.6	-59.3	0	0	0	112.7	L128 I151 A152 L158 I159	L128-F155 HydrophobicContact CD2-CB 3.67Å; I151-F155 HydrophobicContact CG2-CD2 3.49Å; I151-F155 VanDerWaalsContact CG2-CD2 3.49Å; I151-F155 HydrophobicContact CG2-CE2 3.26Å; I151-F155 HydrophobicContact CG2-CZ 4.37Å; I151-F155 VanDerWaalsContact O-CD2 3.27Å; I151-F155 WeakPolarHBondContact O-CD2 3.27Å; I151-F155 PolarHBondContact O-N 3.14Å; A152-F155 PolarHBondContact O-N 3.39Å; F155-L158 PolarHBondContact O-N 3.43Å; F155-I159 VanDerWaalsContact O-CG1 3.31Å; F155-I159 WeakPolarHBondContact O-CG1 3.36Å; F155-I159 PolarHBondContact O-N 3Å
156	I	96.7	Very high	91	Very high	3 Å²	3	71.6 Å²	71.6	2%	0.015	35%	0.346	C	S	.	.	H	α-helix	trans	-61.5	-47.2	175.6	-66.9	168.6	0	0	0	110.2	L61 Y62 W65 A152 K153 L154 L158 I159 Y160	L61-I156 HydrophobicContact CD2-CD1 3.63Å; L61-I156 HydrophobicContact CG-CD1 3.59Å; Y62-I156 HydrophobicContact CD1-CD1 3.6Å; Y62-I156 HydrophobicContact CD1-CG1 3.9Å; Y62-I156 HydrophobicContact CE1-CD1 3.75Å; Y62-I156 HydrophobicContact CE1-CG1 3.79Å; W65-I156 HydrophobicContact CB-CG2 4Å; W65-I156 HydrophobicContact CD2-CG2 3.82Å; W65-I156 HydrophobicContact CE3-CG2 4.45Å; W65-I156 HydrophobicContact CG-CD1 4.37Å; W65-I156 HydrophobicContact CG-CG2 3.6Å; A152-I156 VanDerWaalsContact O-CG1 3.28Å; A152-I156 WeakPolarHBondContact O-CG1 3.49Å; A152-I156 PolarHBondContact O-N 3.49Å; K153-I156 PolarHBondContact O-N 2.87Å; L154-I156 PolarHBondContact O-N 3.35Å; I156-L158 VanDerWaalsContact C-N 3.35Å; I156-L158 PolarHBondContact O-N 3.32Å; I156-I159 PolarHBondContact O-N 3.01Å; I156-Y160 HydrophobicContact CG2-CD2 4.04Å; I156-Y160 HydrophobicContact CG2-CE2 4.09Å; I156-Y160 WeakPolarHBondContact O-CD2 3.36Å; I156-Y160 PolarHBondContact O-N 3.42Å
157	F	97.1	Very high	92.7	Very high	134 Å²	134	65.3 Å²	65.3	59%	0.588	31%	0.314	S	S	*	.	H	α-helix	trans	-58.8	-45.7	177.2	177.6	-100.6	0	0	0	112	K153 L154 I159 Y160 C161	K153-F157 WeakPolarHBondContact O-CB 3.38Å; K153-F157 PolarHBondContact O-N 3.4Å; L154-F157 PolarHBondContact O-N 2.92Å; F157-I159 PolarHBondContact O-N 3.07Å; F157-Y160 PolarHBondContact O-N 3.44Å; F157-C161 VanDerWaalsContact CZ-SG 3.57Å; F157-C161 PolarHBondContact O-N 3.46Å; F157-C161 PolarHBondContact O-SG 3.12Å
158	L	97.6	Very high	94.4	Very high	73 Å²	73	63 Å²	63	38%	0.382	30%	0.302	S	S	.	.	H	α-helix	trans	-61.6	-41.1	176.4	-71.1	175.1	0	0	0	112.2	L154 F155 I156 Y160 C161 I162	L154-L158 HydrophobicContact CD1-CD1 4.42Å; L154-L158 HydrophobicContact CD1-CG 4.39Å; L154-L158 HydrophobicContact CG-CD1 4.08Å; L154-L158 HydrophobicContact CG-CG 4.43Å; L154-L158 WeakPolarHBondContact O-CB 3.04Å; L154-L158 VanDerWaalsContact O-CG 3.29Å; L154-L158 WeakPolarHBondContact O-CG 3.32Å; L154-L158 PolarHBondContact O-N 2.76Å; F155-L158 PolarHBondContact O-N 3.43Å; I156-L158 VanDerWaalsContact C-N 3.35Å; I156-L158 PolarHBondContact O-N 3.32Å; L158-Y160 PolarHBondContact O-N 3.48Å; L158-C161 PolarHBondContact O-N 3.25Å; L158-I162 WeakPolarHBondContact O-CB 3.4Å; L158-I162 WeakPolarHBondContact O-CG1 3.37Å; L158-I162 PolarHBondContact O-N 3.04Å
159	I	97.4	Very high	95	Very high	21 Å²	21	63.2 Å²	63.2	11%	0.108	31%	0.305	C	S	.	.	H	α-helix	trans	-58.5	-48.4	174.5	-74.2	169.4	0	0	0	110.1	F124 I125 L128 F155 I156 F157 C161 I162 C163	F124-I159 HydrophobicContact CB-CD1 4.36Å; F124-I159 HydrophobicContact CB-CG1 4.5Å; F124-I159 HydrophobicContact CB-CG2 3.73Å; I125-I159 HydrophobicContact CG1-CG2 4.31Å; L128-I159 HydrophobicContact CB-CD1 4.03Å; L128-I159 HydrophobicContact CD2-CD1 3.58Å; L128-I159 HydrophobicContact CG-CD1 4.4Å; F155-I159 VanDerWaalsContact O-CG1 3.31Å; F155-I159 WeakPolarHBondContact O-CG1 3.36Å; F155-I159 PolarHBondContact O-N 3Å; I156-I159 PolarHBondContact O-N 3.01Å; F157-I159 PolarHBondContact O-N 3.07Å; I159-C161 PolarHBondContact O-N 3.26Å; I159-I162 PolarHBondContact O-N 2.92Å; I159-C163 VanDerWaalsContact O-CB 3.26Å; I159-C163 WeakPolarHBondContact O-CB 3.35Å; I159-C163 PolarHBondContact O-N 3.42Å; I159-C163 PolarHBondContact O-SG 3.32Å
160	Y	97.2	Very high	95	Very high	36 Å²	36	61.8 Å²	61.8	14%	0.141	30%	0.298	C	S	.	.	H	α-helix	trans	-57.8	-50.1	177.3	-92.5	-100.5	0	0	0	111.7	W65 I121 I125 I156 F157 L158 I162 C163 L164	W65-Y160 HydrophobicContact CB-CE2 4.43Å; W65-Y160 HydrophobicContact CD2-CE2 4.23Å; W65-Y160 HydrophobicContact CE3-CD2 4.36Å; W65-Y160 HydrophobicContact CE3-CE1 4.34Å; W65-Y160 AromaticContact CE3-CE2 3.52Å; W65-Y160 HydrophobicContact CE3-CE2 3.52Å; W65-Y160 AromaticContact CE3-CZ 3.54Å; W65-Y160 HydrophobicContact CZ3-CE1 4.32Å; W65-Y160 HydrophobicContact CZ3-CE2 4.09Å; W65-Y160 AromaticContact CZ3-CZ 3.95Å; W65-Y160 PolarHBondContact O-OH 3.35Å; I121-Y160 HydrophobicContact CD1-CD1 3.62Å; I121-Y160 HydrophobicContact CD1-CE1 3.71Å; I121-Y160 HydrophobicContact CD1-CG 4.09Å; I121-Y160 HydrophobicContact CG2-CD2 4.05Å; I121-Y160 HydrophobicContact CG2-CE1 4.15Å; I121-Y160 HydrophobicContact CG2-CE2 3.56Å; I125-Y160 HydrophobicContact CD1-CE2 3.87Å; I156-Y160 HydrophobicContact CG2-CD2 4.04Å; I156-Y160 HydrophobicContact CG2-CE2 4.09Å; I156-Y160 WeakPolarHBondContact O-CD2 3.36Å; I156-Y160 PolarHBondContact O-N 3.42Å; F157-Y160 PolarHBondContact O-N 3.44Å; L158-Y160 PolarHBondContact O-N 3.48Å; Y160-I162 PolarHBondContact O-N 3.18Å; Y160-C163 PolarHBondContact O-N 3.49Å; Y160-L164 WeakPolarHBondContact O-CB 3.4Å; Y160-L164 WeakPolarHBondContact O-CD1 3.43Å; Y160-L164 WeakPolarHBondContact O-CG 3.38Å; Y160-L164 PolarHBondContact O-N 3.38Å
161	C	97.8	Very high	95.2	Very high	42 Å²	42	55.4 Å²	55.4	28%	0.284	28%	0.277	S	S	.	.	H	α-helix	trans	-60	-48.6	178.8	-67.8	0	0	0	0	112.2	F157 L158 I159 L164 L165	F157-C161 VanDerWaalsContact CZ-SG 3.57Å; F157-C161 PolarHBondContact O-N 3.46Å; F157-C161 PolarHBondContact O-SG 3.12Å; L158-C161 PolarHBondContact O-N 3.25Å; I159-C161 PolarHBondContact O-N 3.26Å; C161-L164 PolarHBondContact O-N 3.28Å; C161-L165 WeakPolarHBondContact O-CB 3.46Å; C161-L165 WeakPolarHBondContact O-CG 3.11Å; C161-L165 PolarHBondContact O-N 3.5Å
162	I	97.5	Very high	95.4	Very high	85 Å²	85	57.5 Å²	57.5	44%	0.436	29%	0.288	S	S	.	.	H	α-helix	trans	-63.6	-46.5	-179	-68.5	166.8	0	0	0	110.4	L158 I159 Y160 L164 L165 L166	L158-I162 WeakPolarHBondContact O-CB 3.4Å; L158-I162 WeakPolarHBondContact O-CG1 3.37Å; L158-I162 PolarHBondContact O-N 3.04Å; I159-I162 PolarHBondContact O-N 2.92Å; Y160-I162 PolarHBondContact O-N 3.18Å; I162-L164 PolarHBondContact O-N 3.16Å; I162-L165 PolarHBondContact O-N 2.99Å; I162-L166 HydrophobicContact CG2-CD1 3.57Å; I162-L166 HydrophobicContact CG2-CG 4.05Å; I162-L166 WeakPolarHBondContact O-CB 3.16Å; I162-L166 VanDerWaalsContact O-CG 3.24Å; I162-L166 WeakPolarHBondContact O-CG 3.38Å; I162-L166 PolarHBondContact O-N 3.02Å
163	C	97.3	Very high	95.4	Very high	1 Å²	1	61.3 Å²	61.3	1%	0.007	30%	0.303	C	S	.	.	H	α-helix	trans	-64.1	-39.4	179.2	-68.2	0	0	0	0	112.4	L120 I121 I159 Y160 N167	L120-C163 HydrophobicContact CD2-CB 3.91Å; L120-C163 HydrophobicContact CG-CB 4.33Å; I121-C163 HydrophobicContact CD1-CB 4.24Å; I121-C163 HydrophobicContact CG1-CB 3.47Å; I121-C163 VanDerWaalsContact CG1-CB 3.47Å; I159-C163 VanDerWaalsContact O-CB 3.26Å; I159-C163 WeakPolarHBondContact O-CB 3.35Å; I159-C163 PolarHBondContact O-N 3.42Å; I159-C163 PolarHBondContact O-SG 3.32Å; Y160-C163 PolarHBondContact O-N 3.49Å; C163-N167 PolarHBondContact O-N 3.26Å; C163-N167 PolarHBondContact O-ND2 3.35Å
164	L	96.8	Very high	95.2	Very high	66 Å²	66	56.2 Å²	56.2	35%	0.346	28%	0.281	S	S	.	.	H	α-helix	trans	-62.8	-43.1	174.7	-74.6	165.9	0	0	0	111.5	Y113 V117 Y160 C161 I162	Y113-L164 HydrophobicContact CE1-CD2 4.06Å; Y113-L164 WeakPolarHBondContact OH-CA 3.16Å; Y113-L164 VanDerWaalsContact OH-CD2 3.23Å; Y113-L164 WeakPolarHBondContact OH-CD2 3.35Å; Y113-L164 PolarHBondContact OH-O 2.95Å; V117-L164 HydrophobicContact CG1-CD2 3.73Å; V117-L164 HydrophobicContact CG1-CG 4.29Å; Y160-L164 WeakPolarHBondContact O-CB 3.4Å; Y160-L164 WeakPolarHBondContact O-CD1 3.43Å; Y160-L164 WeakPolarHBondContact O-CG 3.38Å; Y160-L164 PolarHBondContact O-N 3.38Å; C161-L164 PolarHBondContact O-N 3.28Å; I162-L164 PolarHBondContact O-N 3.16Å
165	L	96.8	Very high	95	Very high	113 Å²	113	53 Å²	53	59%	0.592	27%	0.265	S	S	*	.	H	α-helix	trans	-68.5	-45.1	179.4	-70.7	172.5	0	0	0	112.5	C161 I162 N167 I168	C161-L165 WeakPolarHBondContact O-CB 3.46Å; C161-L165 WeakPolarHBondContact O-CG 3.11Å; C161-L165 PolarHBondContact O-N 3.5Å; I162-L165 PolarHBondContact O-N 2.99Å; L165-N167 PolarHBondContact O-N 2.82Å; L165-I168 HydrophobicContact CD2-CD1 3.83Å; L165-I168 WeakPolarHBondContact O-CB 3.08Å; L165-I168 VanDerWaalsContact O-CG1 3.29Å; L165-I168 WeakPolarHBondContact O-CG1 3.39Å; L165-I168 PolarHBondContact O-N 3.48Å
166	L	95.7	Very high	94.6	Very high	55 Å²	55	50.7 Å²	50.7	29%	0.288	26%	0.256	S	S	.	.	H	α-helix	trans	-62.3	-30	-179.2	-72.2	173.5	0	0	0	112.5	I162 P169 Y198 L202	I162-L166 HydrophobicContact CG2-CD1 3.57Å; I162-L166 HydrophobicContact CG2-CG 4.05Å; I162-L166 WeakPolarHBondContact O-CB 3.16Å; I162-L166 VanDerWaalsContact O-CG 3.24Å; I162-L166 WeakPolarHBondContact O-CG 3.38Å; I162-L166 PolarHBondContact O-N 3.02Å; L166-P169 WeakPolarHBondContact O-CD 3.36Å; L166-Y198 WeakPolarHBondContact CD2-OH 3.38Å; L166-L202 HydrophobicContact CB-CD1 4.26Å; L166-L202 HydrophobicContact CB-CD2 3.87Å; L166-L202 HydrophobicContact CD1-CD1 4.21Å; L166-L202 VanDerWaalsContact O-CD2 3.32Å; L166-L202 WeakPolarHBondContact O-CD2 3.39Å
167	N	95	Very high	94.1	Very high	5 Å²	5	54.8 Å²	54.8	3%	0.027	27%	0.274	C	S	.	.	T	Hydrogen-bonded Turn	trans	-89.4	0.8	-179.7	-75	-68.7	0	0	0	114.3	Y113 V117 L120 C163 L165 P169 H170	Y113-N167 HydrophobicContact CD2-CB 3.97Å; Y113-N167 WeakPolarHBondContact CD2-O 3.32Å; Y113-N167 HydrophobicContact CE2-CB 3.68Å; Y113-N167 WeakPolarHBondContact CE2-O 3.23Å; V117-N167 HydrophobicContact CG2-CB 3.36Å; L120-N167 VanDerWaalsContact CD2-ND2 3.27Å; L120-N167 WeakPolarHBondContact CD2-ND2 3.5Å; C163-N167 PolarHBondContact O-N 3.26Å; C163-N167 PolarHBondContact O-ND2 3.35Å; L165-N167 PolarHBondContact O-N 2.82Å; N167-P169 VanDerWaalsContact O-N 3.14Å; N167-H170 WeakPolarHBondContact O-CB 3.28Å; N167-H170 PolarHBondContact O-N 2.88Å; N167-H170 PolarHBondContact OD1-CD2 3.39Å; N167-H170 PolarHBondContact OD1-NE2 2.9Å
168	I	95.2	Very high	93.4	Very high	72 Å²	72	54 Å²	54	37%	0.369	28%	0.276	S	S	.	.	H	α-helix	trans	-49	-39.4	176.3	-71.8	171.6	0	0	0	112.8	L165 H170 L171 I172	L165-I168 HydrophobicContact CD2-CD1 3.83Å; L165-I168 WeakPolarHBondContact O-CB 3.08Å; L165-I168 VanDerWaalsContact O-CG1 3.29Å; L165-I168 WeakPolarHBondContact O-CG1 3.39Å; L165-I168 PolarHBondContact O-N 3.48Å; I168-H170 PolarHBondContact O-N 3.38Å; I168-H170 VanDerWaalsContact O-N 3.1Å; I168-L171 WeakPolarHBondContact O-CB 3.3Å; I168-L171 PolarHBondContact O-N 3.3Å; I168-I172 HydrophobicContact CG2-CD1 4.24Å
169	P	92.4	Very high	92.2	Very high	26 Å²	26	55.2 Å²	55.2	17%	0.169	28%	0.283	C	S	.	.	H	α-helix	trans	-54.8	-28.3	176.7	-30.6	39.9	0	0	0	114.8	L166 N167 L171 I172 Y173 Y198 V199	L166-P169 WeakPolarHBondContact O-CD 3.36Å; N167-P169 VanDerWaalsContact O-N 3.14Å; P169-L171 VanDerWaalsContact C-N 3.29Å; P169-L171 PolarHBondContact O-N 2.95Å; P169-I172 PolarHBondContact O-N 3.08Å; P169-I172 VanDerWaalsContact O-N 3.1Å; P169-Y173 HydrophobicContact CB-CD2 4.19Å; P169-Y173 HydrophobicContact CB-CE2 4.33Å; P169-Y173 VanDerWaalsContact O-CD2 3.25Å; P169-Y173 WeakPolarHBondContact O-CD2 3.18Å; P169-Y173 PolarHBondContact O-N 3.36Å; P169-Y198 HydrophobicContact CB-CD1 4.27Å; P169-Y198 HydrophobicContact CG-CD1 3.9Å; P169-Y198 HydrophobicContact CG-CE1 3.84Å; P169-V199 HydrophobicContact CB-CG2 3.73Å
170	H	88.8	Confident	91	Very high	2 Å²	2	58 Å²	58	1%	0.009	30%	0.301	C	S	.	.	H	α-helix	trans	-59.5	-39.8	174.1	-77	-89.9	0	0	0	112.4	Y113 D116 N167 I168 I172 A174 Y188 V199	Y113-H170 HydrophobicContact CD2-CB 4.29Å; D116-H170 IonicContact OD2-CE1 3.23Å; D116-H170 PolarHBondContact OD2-CE1 3.31Å; D116-H170 IonicContact OD2-ND1 2.94Å; D116-H170 PolarHBondContact OD2-ND1 3.49Å; D116-H170 IonicContact OD2-NE2 2.75Å; N167-H170 WeakPolarHBondContact O-CB 3.28Å; N167-H170 PolarHBondContact O-N 2.88Å; N167-H170 PolarHBondContact OD1-CD2 3.39Å; N167-H170 PolarHBondContact OD1-NE2 2.9Å; I168-H170 PolarHBondContact O-N 3.38Å; I168-H170 VanDerWaalsContact O-N 3.1Å; H170-I172 PolarHBondContact O-N 3.3Å; H170-A174 VanDerWaalsContact O-CB 3.26Å; H170-A174 WeakPolarHBondContact O-CB 3.39Å; H170-A174 PolarHBondContact O-N 2.91Å; H170-A174 VanDerWaalsContact O-N 3.16Å; H170-Y188 PolarHBondContact CE1-OH 2.87Å; H170-Y188 VanDerWaalsContact CE1-OH 3.3Å; H170-Y188 PolarHBondContact ND1-OH 3.19Å; H170-Y188 VanDerWaalsContact ND1-OH 3.16Å; H170-V199 WeakPolarHBondContact CE1-CG1 3.29Å; H170-V199 WeakPolarHBondContact NE2-CG1 3.08Å
171	L	92.8	Very high	89.3	Confident	58 Å²	58	66.9 Å²	66.9	30%	0.304	34%	0.34	S	S	.	.	H	α-helix	trans	-67.1	-23.3	178.6	-64.7	172.3	0	0	0	112.6	K109 L110 Y113 I168 P169	K109-L171 HydrophobicContact CB-CD2 4.12Å; K109-L171 VanDerWaalsContact CD-O 3.3Å; K109-L171 WeakPolarHBondContact CD-O 3.33Å; K109-L171 WeakPolarHBondContact CE-O 3.22Å; L110-L171 HydrophobicContact CD2-CD2 4.37Å; Y113-L171 HydrophobicContact CD1-CD2 4.24Å; Y113-L171 HydrophobicContact CD2-CD1 3.99Å; Y113-L171 HydrophobicContact CD2-CD2 4.11Å; Y113-L171 HydrophobicContact CD2-CG 3.66Å; Y113-L171 HydrophobicContact CE2-CD1 4.02Å; Y113-L171 HydrophobicContact CE2-CG 4.18Å; Y113-L171 HydrophobicContact CG-CD1 4.23Å; Y113-L171 HydrophobicContact CG-CD2 3.72Å; Y113-L171 HydrophobicContact CG-CG 3.83Å; I168-L171 WeakPolarHBondContact O-CB 3.3Å; I168-L171 PolarHBondContact O-N 3.3Å; P169-L171 VanDerWaalsContact C-N 3.29Å; P169-L171 PolarHBondContact O-N 2.95Å
172	I	93.2	Very high	87.9	Confident	107 Å²	107	73.3 Å²	73.3	55%	0.549	37%	0.366	S	S	.	.	H	α-helix	trans	-88.4	-44.9	-177.7	-58.5	174.4	0	0	0	110.9	I168 P169 H170	I168-I172 HydrophobicContact CG2-CD1 4.24Å; P169-I172 PolarHBondContact O-N 3.08Å; P169-I172 VanDerWaalsContact O-N 3.1Å; H170-I172 PolarHBondContact O-N 3.3Å
173	Y	92.8	Very high	86.7	Confident	81 Å²	81	70.8 Å²	70.8	32%	0.318	36%	0.355	S	S	.	.	H	α-helix	trans	-96.9	-20.8	-168.4	-68.4	-77	0	0	0	115.2	P169 I189 A193 G195 V196	P169-Y173 HydrophobicContact CB-CD2 4.19Å; P169-Y173 HydrophobicContact CB-CE2 4.33Å; P169-Y173 VanDerWaalsContact O-CD2 3.25Å; P169-Y173 WeakPolarHBondContact O-CD2 3.18Å; P169-Y173 PolarHBondContact O-N 3.36Å; Y173-I189 PolarHBondContact O-N 3.4Å; Y173-A193 HydrophobicContact CD1-CB 4.24Å; Y173-A193 HydrophobicContact CE1-CB 4Å; Y173-G195 VanDerWaalsContact CE2-CA 3.46Å; Y173-V196 HydrophobicContact CD1-CG2 4.18Å; Y173-V196 HydrophobicContact CG-CG2 4.08Å
174	A	90	Very high	86	Confident	2 Å²	2	73.2 Å²	73.2	2%	0.017	37%	0.37	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-79.9	128.8	174.9	0	0	0	0	0	109.9	K109 T112 H170 Y188	K109-A174 WeakPolarHBondContact CE-O 3.45Å; K109-A174 WeakPolarHBondContact CG-O 3.27Å; T112-A174 HydrophobicContact CG2-CB 4.49Å; H170-A174 VanDerWaalsContact O-CB 3.26Å; H170-A174 WeakPolarHBondContact O-CB 3.39Å; H170-A174 PolarHBondContact O-N 2.91Å; H170-A174 VanDerWaalsContact O-N 3.16Å; A174-Y188 HydrophobicContact CB-CD1 4.47Å; A174-Y188 HydrophobicContact CB-CE1 4.3Å
175	D	90.8	Very high	85.4	Confident	32 Å²	32	72.2 Å²	72.2	17%	0.171	37%	0.365	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-155.2	176	173.8	-140.9	-33.7	0	0	0	111.7	S105 K109 Q187 I189	S105-D175 VanDerWaalsContact CB-OD1 3.26Å; S105-D175 WeakPolarHBondContact CB-OD1 3.35Å; S105-D175 VanDerWaalsContact OG-CG 3.29Å; S105-D175 PolarHBondContact OG-OD1 3.49Å; S105-D175 PolarHBondContact OG-OD2 3.12Å; K109-D175 WeakPolarHBondContact CE-OD2 3.4Å; K109-D175 IonicContact NZ-OD1 2.72Å; K109-D175 IonicContact NZ-OD2 3.5Å; K109-D175 PolarHBondContact NZ-OD2 3.48Å; D175-Q187 PolarHBondContact N-O 3.27Å; D175-Q187 VanDerWaalsContact N-O 3.12Å; D175-Q187 PolarHBondContact O-N 2.95Å; D175-I189 HydrophobicContact CB-CD1 3.48Å; D175-I189 VanDerWaalsContact CB-CD1 3.48Å; D175-I189 HydrophobicContact CB-CG1 3.58Å
176	L	88.3	Confident	85	Confident	50 Å²	50	68.1 Å²	68.1	26%	0.262	35%	0.345	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-75.1	127.5	173.9	-65.9	169.4	0	0	0	110.1	C108	C108-L176 HydrophobicContact CB-CD2 4.39Å
177	K	86.3	Confident	84.5	Confident	89 Å²	89	68.3 Å²	68.3	39%	0.387	35%	0.345	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-123	131.3	168.7	170.9	175.3	161.1	-160.9	0	109.9	D179 N185 Q187	K177-D179 PolarHBondContact O-N 3.1Å; K177-N185 PolarHBondContact N-O 3.29Å; K177-N185 PolarHBondContact O-N 2.99Å; K177-Q187 HydrophobicContact CB-CG 3.64Å; K177-Q187 VanDerWaalsContact CB-NE2 3.33Å; K177-Q187 HydrophobicContact CD-CG 4.12Å; K177-Q187 HydrophobicContact CG-CG 4.33Å
178	N	82	Confident	84	Confident	118 Å²	118	71.1 Å²	71.1	63%	0.631	36%	0.355	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-78.7	109.9	179.5	-60.3	-3.9	0	0	0	108.3	T184	N178-T184 VanDerWaalsContact OD1-CG2 3.28Å; N178-T184 WeakPolarHBondContact OD1-CG2 3.43Å
179	D	73	Confident	83.5	Confident	98 Å²	98	72.4 Å²	72.4	52%	0.524	36%	0.362	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-83.3	-37.3	-178.6	-148.2	13.6	0	0	0	110.8	K177 T183 N185	K177-D179 PolarHBondContact O-N 3.1Å; D179-T183 PolarHBondContact N-O 3.44Å; D179-N185 PolarHBondContact OD2-ND2 3.14Å
180	T	71.3	Confident	83	Confident	81 Å²	81	75.2 Å²	75.2	50%	0.497	38%	0.376	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-140.1	170	170.6	66.2	0	0	0	0	108.8	E182 T183	T180-E182 PolarHBondContact O-N 2.79Å; T180-T183 PolarHBondContact N-OG1 2.92Å; T180-T183 PolarHBondContact O-N 3.48Å; T180-T183 PolarHBondContact OG1-OG1 3.36Å
181	K	60.5	Low	82.4	Confident	221 Å²	221	79.3 Å²	79.3	96%	0.961	40%	0.402	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.3	-17.4	-179.6	-74.5	-173.8	177.7	-178.8	0	114
182	E	69.2	Low	81.7	Confident	177 Å²	177	81.3 Å²	81.3	83%	0.827	42%	0.417	S	S	*	.	T	Hydrogen-bonded Turn	trans	-119.7	-7.3	-173.3	-63.6	-178.5	177.8	0	0	114.1	T180	T180-E182 PolarHBondContact O-N 2.79Å
183	T	72.9	Confident	81.4	Confident	33 Å²	33	77.1 Å²	77.1	20%	0.202	40%	0.398	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-127.1	113.1	-174.2	65.5	0	0	0	0	112	W97 D179 T180	W97-T183 HydrophobicContact CH2-CG2 3.73Å; W97-T183 HydrophobicContact CZ3-CG2 4.14Å; D179-T183 PolarHBondContact N-O 3.44Å; T180-T183 PolarHBondContact N-OG1 2.92Å; T180-T183 PolarHBondContact O-N 3.48Å; T180-T183 PolarHBondContact OG1-OG1 3.36Å
184	T	81.5	Confident	81.2	Confident	51 Å²	51	76 Å²	76	31%	0.313	41%	0.412	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-93.6	127	169.5	57.3	0	0	0	0	109	S102 N178	S102-T184 VanDerWaalsContact CB-O 3.29Å; S102-T184 WeakPolarHBondContact CB-O 3.39Å; S102-T184 PolarHBondContact OG-O 2.91Å; N178-T184 VanDerWaalsContact OD1-CG2 3.28Å; N178-T184 WeakPolarHBondContact OD1-CG2 3.43Å
185	N	84.7	Confident	81.1	Confident	45 Å²	45	76.5 Å²	76.5	24%	0.241	42%	0.416	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-119.8	138.2	176.6	-70.6	-26.4	0	0	0	109.4	K177 D179 Q187	K177-N185 PolarHBondContact N-O 3.29Å; K177-N185 PolarHBondContact O-N 2.99Å; D179-N185 PolarHBondContact OD2-ND2 3.14Å; N185-Q187 PolarHBondContact O-N 3.45Å
186	C	88	Confident	80.9	Confident	27 Å²	27	75.6 Å²	75.6	18%	0.182	41%	0.412	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-73.4	112.7	170.8	-178.6	0	0	0	0	109.2	D101 C108	D101-C186 HydrophobicContact CB-CB 3.98Å; C108-C186 WeakPolarHBondContact CA-SG 3.27Å; C108-C186 HydrophobicContact CB-CB 3.8Å; C108-C186 WeakPolarHBondContact CB-SG 3.09Å; C108-C186 VanDerWaalsContact SG-CA 3.58Å; C108-C186 WeakPolarHBondContact SG-CB 3.46Å; C108-C186 CovalentContact SG-SG 2.03Å; C108-C186 PolarHBondContact SG-SG 2.87Å
187	Q	86.1	Confident	80.8	Confident	60 Å²	60	77.6 Å²	77.6	28%	0.28	42%	0.418	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-151.5	165.8	179.7	57.1	-178.4	-34.1	0	0	111.3	D175 K177 N185 I189	D175-Q187 PolarHBondContact N-O 3.27Å; D175-Q187 VanDerWaalsContact N-O 3.12Å; D175-Q187 PolarHBondContact O-N 2.95Å; K177-Q187 HydrophobicContact CB-CG 3.64Å; K177-Q187 VanDerWaalsContact CB-NE2 3.33Å; K177-Q187 HydrophobicContact CD-CG 4.12Å; K177-Q187 HydrophobicContact CG-CG 4.33Å; N185-Q187 PolarHBondContact O-N 3.45Å; Q187-I189 PolarHBondContact O-N 2.83Å
188	Y	85	Confident	81.1	Confident	63 Å²	63	78 Å²	78	25%	0.247	42%	0.418	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-68.4	121.3	173.3	-63.4	-67.2	0	0	0	110.1	H170 A174 N190 V196 V199	H170-Y188 PolarHBondContact CE1-OH 2.87Å; H170-Y188 VanDerWaalsContact CE1-OH 3.3Å; H170-Y188 PolarHBondContact ND1-OH 3.19Å; H170-Y188 VanDerWaalsContact ND1-OH 3.16Å; A174-Y188 HydrophobicContact CB-CD1 4.47Å; A174-Y188 HydrophobicContact CB-CE1 4.3Å; Y188-N190 PolarHBondContact O-N 3.17Å; Y188-V196 HydrophobicContact CD1-CG1 4.14Å; Y188-V196 HydrophobicContact CD1-CG2 3.8Å; Y188-V196 HydrophobicContact CD2-CG1 3.75Å; Y188-V196 HydrophobicContact CE2-CG1 4.25Å; Y188-V196 HydrophobicContact CG-CB 4.47Å; Y188-V196 HydrophobicContact CG-CG1 3.7Å; Y188-V196 HydrophobicContact CG-CG2 3.88Å; Y188-V199 HydrophobicContact CE1-CG1 4.44Å; Y188-V199 WeakPolarHBondContact OH-CG1 3.29Å
189	I	83.4	Confident	81.4	Confident	99 Å²	99	72.6 Å²	72.6	51%	0.508	39%	0.389	S	S	.	.	S	Bend	trans	-53.1	-44.6	-176.3	-62.7	167	0	0	0	110.8	Y173 D175 Q187	Y173-I189 PolarHBondContact O-N 3.4Å; D175-I189 HydrophobicContact CB-CD1 3.48Å; D175-I189 VanDerWaalsContact CB-CD1 3.48Å; D175-I189 HydrophobicContact CB-CG1 3.58Å; Q187-I189 PolarHBondContact O-N 2.83Å
190	N	82.3	Confident	82	Confident	86 Å²	86	70.9 Å²	70.9	46%	0.46	38%	0.38	S	S	.	.			trans	-127.9	98.4	176.1	-175.9	-9.7	0	0	0	109.7	Y188 V192 A193 V196	Y188-N190 PolarHBondContact O-N 3.17Å; N190-V192 PolarHBondContact O-N 3.36Å; N190-V192 VanDerWaalsContact O-N 3.1Å; N190-V192 WeakPolarHBondContact OD1-CB 3.37Å; N190-V192 PolarHBondContact OD1-N 3.17Å; N190-A193 HydrophobicContact CB-CB 4.14Å; N190-A193 VanDerWaalsContact O-CB 3.3Å; N190-A193 WeakPolarHBondContact O-CB 2.97Å; N190-A193 PolarHBondContact O-N 2.87Å; N190-A193 VanDerWaalsContact O-N 3.09Å; N190-A193 PolarHBondContact OD1-N 3.35Å; N190-V196 WeakPolarHBondContact O-CG2 3.26Å
191	P	77.1	Confident	82.9	Confident	87 Å²	87	71.4 Å²	71.4	57%	0.565	37%	0.374	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.6	-15.9	-178.2	26.8	-34.7	0	0	0	113.4
192	V	78.3	Confident	84.4	Confident	100 Å²	100	62 Å²	62	61%	0.606	33%	0.334	S	S	*	.	T	Hydrogen-bonded Turn	trans	-89.2	-12.6	-179.8	-169.1	0	0	0	0	111.8	N190 K197	N190-V192 PolarHBondContact O-N 3.36Å; N190-V192 VanDerWaalsContact O-N 3.1Å; N190-V192 WeakPolarHBondContact OD1-CB 3.37Å; N190-V192 PolarHBondContact OD1-N 3.17Å; V192-K197 WeakPolarHBondContact O-CE 3.3Å
193	A	86.3	Confident	85.3	Confident	20 Å²	20	55.4 Å²	55.4	17%	0.165	30%	0.302	C	S	.	.	S	Bend	trans	-59	141.2	-179.1	0	0	0	0	0	111.7	Y173 N190 G195 V196 K197	Y173-A193 HydrophobicContact CD1-CB 4.24Å; Y173-A193 HydrophobicContact CE1-CB 4Å; N190-A193 HydrophobicContact CB-CB 4.14Å; N190-A193 VanDerWaalsContact O-CB 3.3Å; N190-A193 WeakPolarHBondContact O-CB 2.97Å; N190-A193 PolarHBondContact O-N 2.87Å; N190-A193 VanDerWaalsContact O-N 3.09Å; N190-A193 PolarHBondContact OD1-N 3.35Å; A193-G195 PolarHBondContact O-N 3.48Å; A193-G195 VanDerWaalsContact O-N 3.16Å; A193-V196 HydrophobicContact CB-CG2 4.27Å; A193-V196 PolarHBondContact O-N 2.97Å; A193-K197 PolarHBondContact O-N 3.11Å
194	G	87.9	Confident	86	Confident	58 Å²	58	54 Å²	54	60%	0.598	29%	0.293	S	S	*	.	H	α-helix	trans	-56.1	-35	-177.7	0	0	0	0	0	113.3	K197 Y198	G194-K197 WeakPolarHBondContact O-CB 3.23Å; G194-K197 PolarHBondContact O-N 2.9Å; G194-Y198 PolarHBondContact O-N 2.81Å
195	G	88.7	Confident	86.5	Confident	11 Å²	11	56 Å²	56	11%	0.113	30%	0.3	C	S	.	.	H	α-helix	trans	-69.7	-32.6	176.8	0	0	0	0	0	114.6	Y173 A193 K197 Y198 V199	Y173-G195 VanDerWaalsContact CE2-CA 3.46Å; A193-G195 PolarHBondContact O-N 3.48Å; A193-G195 VanDerWaalsContact O-N 3.16Å; G195-K197 VanDerWaalsContact C-N 3.35Å; G195-Y198 WeakPolarHBondContact O-CB 3.47Å; G195-Y198 PolarHBondContact O-N 3.49Å; G195-V199 WeakPolarHBondContact O-CB 3.13Å; G195-V199 WeakPolarHBondContact O-CG2 3.12Å; G195-V199 PolarHBondContact O-N 3.4Å
196	V	85.3	Confident	86.8	Confident	13 Å²	13	54.2 Å²	54.2	8%	0.079	29%	0.292	C	S	.	.	H	α-helix	trans	-68.5	-39	173	-179.2	0	0	0	0	110.3	Y173 Y188 N190 A193 V199 L200	Y173-V196 HydrophobicContact CD1-CG2 4.18Å; Y173-V196 HydrophobicContact CG-CG2 4.08Å; Y188-V196 HydrophobicContact CD1-CG1 4.14Å; Y188-V196 HydrophobicContact CD1-CG2 3.8Å; Y188-V196 HydrophobicContact CD2-CG1 3.75Å; Y188-V196 HydrophobicContact CE2-CG1 4.25Å; Y188-V196 HydrophobicContact CG-CB 4.47Å; Y188-V196 HydrophobicContact CG-CG1 3.7Å; Y188-V196 HydrophobicContact CG-CG2 3.88Å; N190-V196 WeakPolarHBondContact O-CG2 3.26Å; A193-V196 HydrophobicContact CB-CG2 4.27Å; A193-V196 PolarHBondContact O-N 2.97Å; V196-V199 PolarHBondContact O-N 3.29Å; V196-L200 WeakPolarHBondContact O-CB 3.3Å; V196-L200 PolarHBondContact O-N 3.46Å
197	K	87	Confident	86.8	Confident	92 Å²	92	53.5 Å²	53.5	40%	0.4	29%	0.287	S	S	.	.	H	α-helix	trans	-60.6	-46	171.7	-63.9	-179	-179.2	177.7	0	111.1	V192 A193 G194 G195 V199 L200 Y201	V192-K197 WeakPolarHBondContact O-CE 3.3Å; A193-K197 PolarHBondContact O-N 3.11Å; G194-K197 WeakPolarHBondContact O-CB 3.23Å; G194-K197 PolarHBondContact O-N 2.9Å; G195-K197 VanDerWaalsContact C-N 3.35Å; K197-V199 PolarHBondContact O-N 3.03Å; K197-L200 PolarHBondContact O-N 3.05Å; K197-Y201 HydrophobicContact CB-CD2 4.4Å; K197-Y201 HydrophobicContact CB-CE2 4.3Å; K197-Y201 WeakPolarHBondContact O-CD2 3.4Å; K197-Y201 PolarHBondContact O-N 2.97Å
198	Y	92.1	Very high	86.7	Confident	98 Å²	98	50.9 Å²	50.9	38%	0.384	28%	0.276	S	S	.	.	H	α-helix	trans	-56.3	-50.3	175.8	170.6	-91.2	0	0	0	111.7	L166 P169 G194 G195 L200 Y201 L202	L166-Y198 WeakPolarHBondContact CD2-OH 3.38Å; P169-Y198 HydrophobicContact CB-CD1 4.27Å; P169-Y198 HydrophobicContact CG-CD1 3.9Å; P169-Y198 HydrophobicContact CG-CE1 3.84Å; G194-Y198 PolarHBondContact O-N 2.81Å; G195-Y198 WeakPolarHBondContact O-CB 3.47Å; G195-Y198 PolarHBondContact O-N 3.49Å; Y198-L200 VanDerWaalsContact C-N 3.32Å; Y198-L200 PolarHBondContact O-N 3.1Å; Y198-Y201 PolarHBondContact O-N 2.95Å; Y198-L202 HydrophobicContact CE1-CB 4.41Å; Y198-L202 HydrophobicContact CE1-CD2 4.1Å; Y198-L202 WeakPolarHBondContact O-CB 3.26Å; Y198-L202 PolarHBondContact O-N 3.48Å
199	V	89.8	Confident	87	Confident	4 Å²	4	50.5 Å²	50.5	2%	0.024	28%	0.277	C	S	.	.	H	α-helix	trans	-54.3	-48.8	176.7	154.1	0	0	0	0	111.3	P169 H170 Y188 G195 V196 K197 Y201 L202 Y203	P169-V199 HydrophobicContact CB-CG2 3.73Å; H170-V199 WeakPolarHBondContact CE1-CG1 3.29Å; H170-V199 WeakPolarHBondContact NE2-CG1 3.08Å; Y188-V199 HydrophobicContact CE1-CG1 4.44Å; Y188-V199 WeakPolarHBondContact OH-CG1 3.29Å; G195-V199 WeakPolarHBondContact O-CB 3.13Å; G195-V199 WeakPolarHBondContact O-CG2 3.12Å; G195-V199 PolarHBondContact O-N 3.4Å; V196-V199 PolarHBondContact O-N 3.29Å; K197-V199 PolarHBondContact O-N 3.03Å; V199-Y201 VanDerWaalsContact C-N 3.35Å; V199-Y201 PolarHBondContact O-N 3.48Å; V199-L202 PolarHBondContact O-N 3.04Å; V199-Y203 PolarHBondContact O-N 3.36Å
200	L	85.7	Confident	87.4	Confident	63 Å²	63	49.2 Å²	49.2	33%	0.33	27%	0.271	S	S	.	.	H	α-helix	trans	-63.1	-41.8	179.7	-174	67.7	0	0	0	111.8	V196 K197 Y198 Y203 I204 Q275	V196-L200 WeakPolarHBondContact O-CB 3.3Å; V196-L200 PolarHBondContact O-N 3.46Å; K197-L200 PolarHBondContact O-N 3.05Å; Y198-L200 VanDerWaalsContact C-N 3.32Å; Y198-L200 PolarHBondContact O-N 3.1Å; L200-Y203 PolarHBondContact O-N 3.02Å; L200-I204 HydrophobicContact CD1-CD1 4.16Å; L200-I204 HydrophobicContact CG-CD1 4.07Å; L200-I204 WeakPolarHBondContact O-CG1 3.46Å; L200-I204 PolarHBondContact O-N 3.09Å; L200-Q275 HydrophobicContact CD2-CG 4Å; L200-Q275 HydrophobicContact CG-CG 4.48Å
201	Y	89.6	Confident	87.9	Confident	92 Å²	92	45.1 Å²	45.1	36%	0.361	25%	0.249	S	C	.	.	H	α-helix	trans	-68.4	-37.8	175.7	-75.7	-59	0	0	0	112.8	K197 Y198 V199 Y203 I204 I205 F279	K197-Y201 HydrophobicContact CB-CD2 4.4Å; K197-Y201 HydrophobicContact CB-CE2 4.3Å; K197-Y201 WeakPolarHBondContact O-CD2 3.4Å; K197-Y201 PolarHBondContact O-N 2.97Å; Y198-Y201 PolarHBondContact O-N 2.95Å; V199-Y201 VanDerWaalsContact C-N 3.35Å; V199-Y201 PolarHBondContact O-N 3.48Å; Y201-Y203 VanDerWaalsContact C-N 3.33Å; Y201-I204 PolarHBondContact O-N 3.17Å; Y201-I205 VanDerWaalsContact O-CB 3.28Å; Y201-I205 WeakPolarHBondContact O-CB 3.43Å; Y201-I205 WeakPolarHBondContact O-CG1 3.25Å; Y201-I205 PolarHBondContact O-N 2.94Å; Y201-F279 AromaticContact CZ-CZ 3.9Å; Y201-F279 WeakPolarHBondContact OH-CZ 3.42Å
202	L	92.7	Very high	88.5	Confident	23 Å²	23	41.9 Å²	41.9	12%	0.12	23%	0.228	C	C	.	.	I	π-helix	trans	-61.9	-44.2	175.5	179	68.2	0	0	0	110.3	L166 Y198 V199 G206	L166-L202 HydrophobicContact CB-CD1 4.26Å; L166-L202 HydrophobicContact CB-CD2 3.87Å; L166-L202 HydrophobicContact CD1-CD1 4.21Å; L166-L202 VanDerWaalsContact O-CD2 3.32Å; L166-L202 WeakPolarHBondContact O-CD2 3.39Å; Y198-L202 HydrophobicContact CE1-CB 4.41Å; Y198-L202 HydrophobicContact CE1-CD2 4.1Å; Y198-L202 WeakPolarHBondContact O-CB 3.26Å; Y198-L202 PolarHBondContact O-N 3.48Å; V199-L202 PolarHBondContact O-N 3.04Å; L202-G206 WeakPolarHBondContact O-CA 3.22Å; L202-G206 PolarHBondContact O-N 2.75Å
203	Y	87.9	Confident	89.1	Confident	39 Å²	39	41.6 Å²	41.6	15%	0.153	22%	0.222	C	C	.	.	I	π-helix	trans	-60.9	-52	175	-174.4	-93.4	0	0	0	111.1	V199 L200 Y201 V207 T208	V199-Y203 PolarHBondContact O-N 3.36Å; L200-Y203 PolarHBondContact O-N 3.02Å; Y201-Y203 VanDerWaalsContact C-N 3.33Å; Y203-V207 HydrophobicContact CD2-CB 4.26Å; Y203-V207 HydrophobicContact CD2-CG2 3.75Å; Y203-V207 HydrophobicContact CE2-CB 4.34Å; Y203-V207 HydrophobicContact CE2-CG1 4.31Å; Y203-V207 HydrophobicContact CE2-CG2 4.11Å; Y203-V207 HydrophobicContact CG-CG2 4.29Å; Y203-V207 WeakPolarHBondContact O-CA 3.47Å; Y203-V207 WeakPolarHBondContact O-CB 3.47Å; Y203-V207 PolarHBondContact O-N 3.49Å; Y203-T208 HydrophobicContact CE1-CG2 4.14Å; Y203-T208 PolarHBondContact O-N 3.39Å
204	I	86.4	Confident	89.5	Confident	4 Å²	4	43 Å²	43	2%	0.021	23%	0.227	C	C	.	.	I	π-helix	trans	-67.2	-50.3	-175	-72.9	165.4	0	0	0	111.7	L200 Y201 T208 I209 M271 Q275	L200-I204 HydrophobicContact CD1-CD1 4.16Å; L200-I204 HydrophobicContact CG-CD1 4.07Å; L200-I204 WeakPolarHBondContact O-CG1 3.46Å; L200-I204 PolarHBondContact O-N 3.09Å; Y201-I204 PolarHBondContact O-N 3.17Å; I204-T208 PolarHBondContact O-N 2.93Å; I204-T208 PolarHBondContact O-OG1 2.96Å; I204-I209 HydrophobicContact CG2-CD1 3.65Å; I204-I209 HydrophobicContact CG2-CG1 4.21Å; I204-I209 WeakPolarHBondContact O-CG1 3.04Å; I204-I209 PolarHBondContact O-N 2.89Å; I204-M271 HydrophobicContact CD1-CB 4.26Å; I204-M271 HydrophobicContact CG1-CB 4.16Å; I204-Q275 HydrophobicContact CD1-CG 3.53Å
205	I	91.6	Very high	89.8	Confident	92 Å²	92	40.3 Å²	40.3	47%	0.472	20%	0.199	S	C	.	.	I	π-helix	trans	-73	-49.1	-178.7	-61	172.6	0	0	0	109.9	Y201 L210	Y201-I205 VanDerWaalsContact O-CB 3.28Å; Y201-I205 WeakPolarHBondContact O-CB 3.43Å; Y201-I205 WeakPolarHBondContact O-CG1 3.25Å; Y201-I205 PolarHBondContact O-N 2.94Å; I205-L210 WeakPolarHBondContact O-CB 3.3Å; I205-L210 PolarHBondContact O-N 2.96Å
206	G	90.9	Very high	89.9	Confident	7 Å²	7	45.3 Å²	45.3	7%	0.072	22%	0.218	C	C	.	.	I	π-helix	trans	-78.7	-43.6	-170.6	0	0	0	0	0	114.6	F124 L202 P211	F124-G206 VanDerWaalsContact CE2-O 3.23Å; F124-G206 WeakPolarHBondContact CE2-O 3.23Å; L202-G206 WeakPolarHBondContact O-CA 3.22Å; L202-G206 PolarHBondContact O-N 2.75Å; G206-P211 WeakPolarHBondContact O-CD 3.47Å; G206-P211 WeakPolarHBondContact O-CG 3.45Å
207	V	88.2	Confident	90.3	Very high	13 Å²	13	48.4 Å²	48.4	8%	0.079	23%	0.233	C	C	.	.	I	π-helix	trans	-83	-37	179.9	-174.7	0	0	0	0	110.7	A119 L120 A123 Y203 P211	A119-V207 HydrophobicContact CB-CG1 4.25Å; L120-V207 HydrophobicContact CB-CG2 4Å; L120-V207 HydrophobicContact CD1-CB 4.43Å; L120-V207 HydrophobicContact CD1-CG2 3.5Å; L120-V207 HydrophobicContact CG-CG2 4.37Å; A123-V207 HydrophobicContact CB-CG1 4.34Å; Y203-V207 HydrophobicContact CD2-CB 4.26Å; Y203-V207 HydrophobicContact CD2-CG2 3.75Å; Y203-V207 HydrophobicContact CE2-CB 4.34Å; Y203-V207 HydrophobicContact CE2-CG1 4.31Å; Y203-V207 HydrophobicContact CE2-CG2 4.11Å; Y203-V207 HydrophobicContact CG-CG2 4.29Å; Y203-V207 WeakPolarHBondContact O-CA 3.47Å; Y203-V207 WeakPolarHBondContact O-CB 3.47Å; Y203-V207 PolarHBondContact O-N 3.49Å; V207-P211 WeakPolarHBondContact O-CG 3.37Å
208	T	85.7	Confident	90.7	Very high	5 Å²	5	45.5 Å²	45.5	3%	0.031	22%	0.221	C	C	.	.	I	π-helix	trans	-109	-65.5	-165.8	82.6	0	0	0	0	114	Y203 I204 S212 V268	Y203-T208 HydrophobicContact CE1-CG2 4.14Å; Y203-T208 PolarHBondContact O-N 3.39Å; I204-T208 PolarHBondContact O-N 2.93Å; I204-T208 PolarHBondContact O-OG1 2.96Å; T208-S212 WeakPolarHBondContact O-CB 3.36Å; T208-S212 PolarHBondContact O-N 2.97Å; T208-S212 PolarHBondContact O-OG 2.84Å; T208-V268 HydrophobicContact CG2-CG2 4.4Å
209	I	89.4	Confident	90.7	Very high	55 Å²	55	41.5 Å²	41.5	28%	0.282	21%	0.207	S	C	.	.	I	π-helix	trans	-67.5	-52.1	-169.8	-64.2	175.5	0	0	0	111.4	I204 S212 I213 V268 I272	I204-I209 HydrophobicContact CG2-CD1 3.65Å; I204-I209 HydrophobicContact CG2-CG1 4.21Å; I204-I209 WeakPolarHBondContact O-CG1 3.04Å; I204-I209 PolarHBondContact O-N 2.89Å; I209-S212 PolarHBondContact O-N 3.42Å; I209-I213 HydrophobicContact CG2-CD1 3.62Å; I209-I213 HydrophobicContact CG2-CG1 4.45Å; I209-I213 WeakPolarHBondContact O-CB 3.47Å; I209-I213 VanDerWaalsContact O-CG1 3.31Å; I209-I213 WeakPolarHBondContact O-CG1 3.41Å; I209-I213 PolarHBondContact O-N 3.09Å; I209-V268 HydrophobicContact CG1-CG1 4.07Å; I209-I272 HydrophobicContact CD1-CD1 4.46Å
210	L	93.4	Very high	90.8	Very high	72 Å²	72	44.4 Å²	44.4	38%	0.377	22%	0.221	S	C	.	.	H	α-helix	trans	-64.2	-51	-175.5	175.8	71.4	0	0	0	111.7	F124 I205 S212 L214	F124-L210 HydrophobicContact CZ-CD2 4.43Å; I205-L210 WeakPolarHBondContact O-CB 3.3Å; I205-L210 PolarHBondContact O-N 2.96Å; L210-S212 PolarHBondContact O-N 3.35Å; L210-L214 HydrophobicContact CD1-CD1 3.65Å; L210-L214 HydrophobicContact CD1-CG 4.31Å; L210-L214 HydrophobicContact CG-CD1 4.03Å; L210-L214 WeakPolarHBondContact O-CB 3.35Å; L210-L214 WeakPolarHBondContact O-CG 3.44Å; L210-L214 PolarHBondContact O-N 3.48Å; L210-L214 VanDerWaalsContact O-N 3.14Å
211	P	92.6	Very high	91.2	Very high	0 Å²	0	44.3 Å²	44.3	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-62.2	-42.7	175.8	-25.8	38.2	0	0	0	112.3	A123 G206 V207 I213 L214 I215	A123-P211 HydrophobicContact CB-CB 4.07Å; A123-P211 HydrophobicContact CB-CG 3.81Å; G206-P211 WeakPolarHBondContact O-CD 3.47Å; G206-P211 WeakPolarHBondContact O-CG 3.45Å; V207-P211 WeakPolarHBondContact O-CG 3.37Å; P211-I213 PolarHBondContact O-N 3.49Å; P211-L214 PolarHBondContact O-N 3.31Å; P211-I215 HydrophobicContact CB-CD1 4.2Å; P211-I215 WeakPolarHBondContact O-CB 3.42Å; P211-I215 WeakPolarHBondContact O-CD1 3.4Å; P211-I215 WeakPolarHBondContact O-CG1 3.42Å; P211-I215 PolarHBondContact O-N 3.49Å
212	S	89	Confident	91.3	Very high	18 Å²	18	39.9 Å²	39.9	13%	0.126	20%	0.203	C	C	.	.	H	α-helix	trans	-62.8	-46.2	-178	-61.6	0	0	0	0	112.5	T208 I209 L210 F216	T208-S212 WeakPolarHBondContact O-CB 3.36Å; T208-S212 PolarHBondContact O-N 2.97Å; T208-S212 PolarHBondContact O-OG 2.84Å; I209-S212 PolarHBondContact O-N 3.42Å; L210-S212 PolarHBondContact O-N 3.35Å; S212-F216 WeakPolarHBondContact O-CB 3.02Å; S212-F216 PolarHBondContact O-N 2.8Å
213	I	91.3	Very high	91.2	Very high	94 Å²	94	41.2 Å²	41.2	48%	0.482	22%	0.215	S	C	.	.	H	α-helix	trans	-64.2	-45.7	179	-67.8	172.2	0	0	0	110.4	I209 P211 F216 I217	I209-I213 HydrophobicContact CG2-CD1 3.62Å; I209-I213 HydrophobicContact CG2-CG1 4.45Å; I209-I213 WeakPolarHBondContact O-CB 3.47Å; I209-I213 VanDerWaalsContact O-CG1 3.31Å; I209-I213 WeakPolarHBondContact O-CG1 3.41Å; I209-I213 PolarHBondContact O-N 3.09Å; P211-I213 PolarHBondContact O-N 3.49Å; I213-F216 PolarHBondContact O-N 2.9Å; I213-I217 HydrophobicContact CG2-CD1 3.83Å; I213-I217 VanDerWaalsContact O-CG1 3.3Å; I213-I217 WeakPolarHBondContact O-CG1 3.37Å; I213-I217 PolarHBondContact O-N 3.37Å
214	L	94.1	Very high	91.4	Very high	51 Å²	51	45.7 Å²	45.7	27%	0.267	24%	0.235	S	C	.	.	H	α-helix	trans	-67	-45.4	-179.1	-73.3	173.2	0	0	0	111.9	M127 L210 P211 F216 I217 M218	M127-L214 HydrophobicContact CG-CB 4.1Å; M127-L214 HydrophobicContact CG-CD1 4.06Å; M127-L214 HydrophobicContact SD-CB 4.26Å; M127-L214 HydrophobicContact SD-CD1 3.3Å; M127-L214 WeakPolarHBondContact SD-CD1 3.45Å; M127-L214 HydrophobicContact SD-CG 4.39Å; L210-L214 HydrophobicContact CD1-CD1 3.65Å; L210-L214 HydrophobicContact CD1-CG 4.31Å; L210-L214 HydrophobicContact CG-CD1 4.03Å; L210-L214 WeakPolarHBondContact O-CB 3.35Å; L210-L214 WeakPolarHBondContact O-CG 3.44Å; L210-L214 PolarHBondContact O-N 3.48Å; L210-L214 VanDerWaalsContact O-N 3.14Å; P211-L214 PolarHBondContact O-N 3.31Å; L214-F216 VanDerWaalsContact C-N 3.31Å; L214-F216 PolarHBondContact O-N 3.4Å; L214-I217 PolarHBondContact O-N 3.19Å; L214-M218 WeakPolarHBondContact O-CB 3.37Å; L214-M218 WeakPolarHBondContact O-CG 3.02Å; L214-M218 PolarHBondContact O-N 2.77Å
215	I	93.5	Very high	91.4	Very high	0 Å²	0	48.6 Å²	48.6	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-59.9	-43.2	175.7	-70.4	165.1	0	0	0	110.4	L126 P211 M218 N219 F260	L126-I215 HydrophobicContact CB-CD1 4.31Å; L126-I215 HydrophobicContact CD2-CD1 3.67Å; L126-I215 HydrophobicContact CG-CD1 3.71Å; P211-I215 HydrophobicContact CB-CD1 4.2Å; P211-I215 WeakPolarHBondContact O-CB 3.42Å; P211-I215 WeakPolarHBondContact O-CD1 3.4Å; P211-I215 WeakPolarHBondContact O-CG1 3.42Å; P211-I215 PolarHBondContact O-N 3.49Å; I215-M218 PolarHBondContact O-N 2.76Å; I215-N219 VanDerWaalsContact O-CB 3.26Å; I215-N219 WeakPolarHBondContact O-CB 3.01Å; I215-N219 PolarHBondContact O-N 3.38Å; I215-F260 HydrophobicContact CD1-CD1 3.76Å; I215-F260 HydrophobicContact CD1-CE1 3.63Å
216	F	91.6	Very high	91.2	Very high	117 Å²	117	45.7 Å²	45.7	51%	0.513	23%	0.233	S	C	.	.	H	α-helix	trans	-60.4	-49.1	177.7	-178.3	-104.2	0	0	0	112.2	S212 I213 L214 M218 N219 I220	S212-F216 WeakPolarHBondContact O-CB 3.02Å; S212-F216 PolarHBondContact O-N 2.8Å; I213-F216 PolarHBondContact O-N 2.9Å; L214-F216 VanDerWaalsContact C-N 3.31Å; L214-F216 PolarHBondContact O-N 3.4Å; F216-M218 PolarHBondContact O-N 2.88Å; F216-N219 PolarHBondContact O-N 2.65Å; F216-I220 HydrophobicContact CD1-CD1 3.85Å; F216-I220 HydrophobicContact CE1-CD1 3.39Å; F216-I220 HydrophobicContact CE2-CD1 4.33Å; F216-I220 HydrophobicContact CG-CD1 4.49Å; F216-I220 HydrophobicContact CZ-CD1 3.68Å; F216-I220 WeakPolarHBondContact O-CG1 3.21Å; F216-I220 PolarHBondContact O-N 3.44Å
217	I	94	Very high	91.1	Very high	78 Å²	78	53 Å²	53	40%	0.4	26%	0.262	S	S	.	.	H	α-helix	trans	-61	-46.3	176.8	-66.6	167.1	0	0	0	110.5	I213 L214 N219 I220 L221	I213-I217 HydrophobicContact CG2-CD1 3.83Å; I213-I217 VanDerWaalsContact O-CG1 3.3Å; I213-I217 WeakPolarHBondContact O-CG1 3.37Å; I213-I217 PolarHBondContact O-N 3.37Å; L214-I217 PolarHBondContact O-N 3.19Å; I217-N219 VanDerWaalsContact C-N 3.35Å; I217-N219 PolarHBondContact O-N 3.02Å; I217-I220 WeakPolarHBondContact O-CB 3.17Å; I217-I220 PolarHBondContact O-N 3.38Å; I217-L221 HydrophobicContact CG2-CD1 4.32Å; I217-L221 WeakPolarHBondContact O-CG 3.45Å; I217-L221 PolarHBondContact O-N 2.73Å
218	M	94.3	Very high	91.1	Very high	31 Å²	31	55.6 Å²	55.6	15%	0.153	28%	0.278	C	S	.	.	H	α-helix	trans	-62.9	-40.8	179.6	-66.7	-64.7	162.1	0	0	111.5	I131 V134 L214 I215 F216 I220 L221 I222	I131-M218 HydrophobicContact CG1-CE 3.89Å; I131-M218 HydrophobicContact CG1-SD 4.37Å; V134-M218 HydrophobicContact CB-SD 3.93Å; V134-M218 HydrophobicContact CG1-SD 4.25Å; V134-M218 HydrophobicContact CG2-CB 4.04Å; V134-M218 HydrophobicContact CG2-CG 4.37Å; V134-M218 HydrophobicContact CG2-SD 3.55Å; V134-M218 VanDerWaalsContact CG2-SD 3.55Å; L214-M218 WeakPolarHBondContact O-CB 3.37Å; L214-M218 WeakPolarHBondContact O-CG 3.02Å; L214-M218 PolarHBondContact O-N 2.77Å; I215-M218 PolarHBondContact O-N 2.76Å; F216-M218 PolarHBondContact O-N 2.88Å; M218-I220 VanDerWaalsContact C-N 3.33Å; M218-I220 PolarHBondContact O-N 2.87Å; M218-L221 PolarHBondContact O-N 2.93Å; M218-L221 HydrophobicContact SD-CD1 4.34Å; M218-I222 VanDerWaalsContact O-CG1 3.24Å; M218-I222 WeakPolarHBondContact O-CG1 3.44Å; M218-I222 PolarHBondContact O-N 2.61Å
219	N	92.4	Very high	90.9	Very high	14 Å²	14	57 Å²	57	8%	0.075	29%	0.287	C	S	.	.	H	α-helix	trans	-63	-37.8	176.4	-79.7	-11.5	0	0	0	113	I215 F216 I217 S223 L254 S257	I215-N219 VanDerWaalsContact O-CB 3.26Å; I215-N219 WeakPolarHBondContact O-CB 3.01Å; I215-N219 PolarHBondContact O-N 3.38Å; F216-N219 PolarHBondContact O-N 2.65Å; I217-N219 VanDerWaalsContact C-N 3.35Å; I217-N219 PolarHBondContact O-N 3.02Å; N219-S223 VanDerWaalsContact O-CB 3.28Å; N219-S223 WeakPolarHBondContact O-CB 3.32Å; N219-S223 PolarHBondContact O-N 3.45Å; N219-S223 PolarHBondContact O-OG 3.03Å; N219-L254 HydrophobicContact CB-CD1 4Å; N219-S257 WeakPolarHBondContact ND2-CB 3.33Å; N219-S257 PolarHBondContact ND2-OG 2.59Å; N219-S257 PolarHBondContact OD1-OG 2.98Å
220	I	93.2	Very high	90.5	Very high	65 Å²	65	56.6 Å²	56.6	33%	0.333	29%	0.285	S	S	.	.	H	α-helix	trans	-61.7	-48.4	172.6	-71.2	171.4	0	0	0	110.1	F216 I217 M218 S223 F224	F216-I220 HydrophobicContact CD1-CD1 3.85Å; F216-I220 HydrophobicContact CE1-CD1 3.39Å; F216-I220 HydrophobicContact CE2-CD1 4.33Å; F216-I220 HydrophobicContact CG-CD1 4.49Å; F216-I220 HydrophobicContact CZ-CD1 3.68Å; F216-I220 WeakPolarHBondContact O-CG1 3.21Å; F216-I220 PolarHBondContact O-N 3.44Å; I217-I220 WeakPolarHBondContact O-CB 3.17Å; I217-I220 PolarHBondContact O-N 3.38Å; M218-I220 VanDerWaalsContact C-N 3.33Å; M218-I220 PolarHBondContact O-N 2.87Å; I220-S223 PolarHBondContact O-N 3.25Å; I220-F224 HydrophobicContact CG2-CD2 3.54Å; I220-F224 HydrophobicContact CG2-CE2 3.19Å; I220-F224 HydrophobicContact CG2-CZ 4.18Å; I220-F224 VanDerWaalsContact O-CD2 3.23Å; I220-F224 WeakPolarHBondContact O-CD2 3.35Å; I220-F224 PolarHBondContact O-N 3.01Å
221	L	94	Very high	90.2	Very high	60 Å²	60	60.3 Å²	60.3	31%	0.314	30%	0.298	S	S	.	.	H	α-helix	trans	-61.4	-45.5	178.6	-65.9	174.8	0	0	0	112.2	V134 Y138 I217 M218 S223 F224 K225	V134-L221 HydrophobicContact CG1-CD1 4.34Å; V134-L221 HydrophobicContact CG2-CB 4.26Å; Y138-L221 HydrophobicContact CE2-CB 4.45Å; I217-L221 HydrophobicContact CG2-CD1 4.32Å; I217-L221 WeakPolarHBondContact O-CG 3.45Å; I217-L221 PolarHBondContact O-N 2.73Å; M218-L221 PolarHBondContact O-N 2.93Å; M218-L221 HydrophobicContact SD-CD1 4.34Å; L221-S223 VanDerWaalsContact C-N 3.33Å; L221-S223 PolarHBondContact O-N 2.91Å; L221-F224 PolarHBondContact O-N 3.25Å; L221-K225 WeakPolarHBondContact O-CB 3.48Å; L221-K225 PolarHBondContact O-N 3.07Å; L221-K225 VanDerWaalsContact O-N 3.08Å
222	I	90.7	Very high	89.6	Confident	0 Å²	0	65.3 Å²	65.3	0%	0	32%	0.321	C	S	.	.	H	α-helix	trans	-57.7	-47.4	175.2	-68.7	168.1	0	0	0	109.9	R133 V134 I137 M218 K225 L226 V250	R133-I222 HydrophobicContact CB-CD1 3.95Å; V134-I222 HydrophobicContact CG2-CD1 4.11Å; V134-I222 HydrophobicContact CG2-CG1 3.62Å; I137-I222 HydrophobicContact CD1-CG1 4.17Å; I137-I222 HydrophobicContact CD1-CG2 4.08Å; M218-I222 VanDerWaalsContact O-CG1 3.24Å; M218-I222 WeakPolarHBondContact O-CG1 3.44Å; M218-I222 PolarHBondContact O-N 2.61Å; I222-K225 PolarHBondContact O-N 3.47Å; I222-L226 WeakPolarHBondContact O-CB 3.25Å; I222-L226 PolarHBondContact O-N 2.91Å; I222-V250 HydrophobicContact CG2-CG1 3.51Å
223	S	90.6	Very high	89	Confident	51 Å²	51	67.3 Å²	67.3	36%	0.357	34%	0.335	S	S	.	.	H	α-helix	trans	-64.4	-43.5	-177.6	-62	0	0	0	0	112.5	N219 I220 L221 L226 K227	N219-S223 VanDerWaalsContact O-CB 3.28Å; N219-S223 WeakPolarHBondContact O-CB 3.32Å; N219-S223 PolarHBondContact O-N 3.45Å; N219-S223 PolarHBondContact O-OG 3.03Å; I220-S223 PolarHBondContact O-N 3.25Å; L221-S223 VanDerWaalsContact C-N 3.33Å; L221-S223 PolarHBondContact O-N 2.91Å; S223-L226 PolarHBondContact O-N 3.38Å; S223-K227 WeakPolarHBondContact O-CB 3.31Å; S223-K227 PolarHBondContact O-N 3.41Å
224	F	91.5	Very high	88.4	Confident	133 Å²	133	69.7 Å²	69.7	58%	0.583	34%	0.342	S	S	*	.	H	α-helix	trans	-61.7	-47.7	176.6	-78.4	-52.3	0	0	0	111.9	I220 L221 K227 T228	I220-F224 HydrophobicContact CG2-CD2 3.54Å; I220-F224 HydrophobicContact CG2-CE2 3.19Å; I220-F224 HydrophobicContact CG2-CZ 4.18Å; I220-F224 VanDerWaalsContact O-CD2 3.23Å; I220-F224 WeakPolarHBondContact O-CD2 3.35Å; I220-F224 PolarHBondContact O-N 3.01Å; L221-F224 PolarHBondContact O-N 3.25Å; F224-K227 PolarHBondContact O-N 3.08Å; F224-T228 PolarHBondContact O-N 3.05Å; F224-T228 VanDerWaalsContact O-N 3.1Å; F224-T228 PolarHBondContact O-OG1 3.26Å; F224-T228 VanDerWaalsContact O-OG1 3.14Å
225	K	88.3	Confident	87.7	Confident	64 Å²	64	73.4 Å²	73.4	28%	0.278	36%	0.361	S	S	.	.	H	α-helix	trans	-71.2	-33.5	-178.7	-172.4	56.5	173.6	-161.9	0	112.1	I137 Y138 L221 I222 T228 T229	I137-K225 HydrophobicContact CG2-CB 3.9Å; I137-K225 HydrophobicContact CG2-CD 4.39Å; I137-K225 HydrophobicContact CG2-CG 3.18Å; Y138-K225 HydrophobicContact CE2-CB 4.01Å; Y138-K225 HydrophobicContact CE2-CG 4.13Å; L221-K225 WeakPolarHBondContact O-CB 3.48Å; L221-K225 PolarHBondContact O-N 3.07Å; L221-K225 VanDerWaalsContact O-N 3.08Å; I222-K225 PolarHBondContact O-N 3.47Å; K225-T228 PolarHBondContact O-N 2.9Å; K225-T229 WeakPolarHBondContact O-CB 3.42Å; K225-T229 PolarHBondContact O-N 3.41Å; K225-T229 PolarHBondContact O-OG1 2.81Å
226	L	87	Confident	86.7	Confident	31 Å²	31	78.4 Å²	78.4	16%	0.162	39%	0.388	C	S	.	.	H	α-helix	trans	-63.6	-45.5	172.9	179.2	60.9	0	0	0	111.4	I222 S223 T228 T229 I230 L247	I222-L226 WeakPolarHBondContact O-CB 3.25Å; I222-L226 PolarHBondContact O-N 2.91Å; S223-L226 PolarHBondContact O-N 3.38Å; L226-T228 VanDerWaalsContact C-N 3.32Å; L226-T228 PolarHBondContact O-N 3.44Å; L226-T229 PolarHBondContact O-N 2.96Å; L226-T229 VanDerWaalsContact O-N 3.16Å; L226-I230 HydrophobicContact CD1-CD1 3.85Å; L226-I230 HydrophobicContact CD1-CG1 4.04Å; L226-I230 HydrophobicContact CD2-CD1 4.43Å; L226-I230 HydrophobicContact CG-CD1 3.81Å; L226-I230 HydrophobicContact CG-CG1 4.39Å; L226-I230 WeakPolarHBondContact O-CG1 3.26Å; L226-I230 PolarHBondContact O-N 3.1Å; L226-L247 HydrophobicContact CD1-CD1 3.24Å; L226-L247 HydrophobicContact CD2-CD1 4.38Å; L226-L247 HydrophobicContact CG-CD1 4.41Å
227	K	89.1	Confident	85.5	Confident	160 Å²	160	75.8 Å²	75.8	70%	0.696	40%	0.395	S	S	*	.	H	α-helix	trans	-58.1	-44.7	175.6	-175.3	177.8	-179.8	177.7	0	111.6	S223 F224 K231	S223-K227 WeakPolarHBondContact O-CB 3.31Å; S223-K227 PolarHBondContact O-N 3.41Å; F224-K227 PolarHBondContact O-N 3.08Å; K227-K231 WeakPolarHBondContact O-CB 3.32Å; K227-K231 PolarHBondContact O-N 2.68Å
228	T	86.6	Confident	84	Confident	68 Å²	68	79.6 Å²	79.6	42%	0.417	41%	0.405	S	S	.	.	H	α-helix	trans	-61.5	-45.3	175.3	-60.3	0	0	0	0	111.2	F224 K225 L226 K231 H232	F224-T228 PolarHBondContact O-N 3.05Å; F224-T228 VanDerWaalsContact O-N 3.1Å; F224-T228 PolarHBondContact O-OG1 3.26Å; F224-T228 VanDerWaalsContact O-OG1 3.14Å; K225-T228 PolarHBondContact O-N 2.9Å; L226-T228 VanDerWaalsContact C-N 3.32Å; L226-T228 PolarHBondContact O-N 3.44Å; T228-K231 PolarHBondContact O-N 3.5Å; T228-H232 PolarHBondContact O-CD2 3.34Å; T228-H232 PolarHBondContact O-N 2.9Å
229	T	81.3	Confident	82.7	Confident	35 Å²	35	89.5 Å²	89.5	22%	0.215	44%	0.442	C	S	.	.	H	α-helix	trans	-64.3	-45	-179.6	-56.6	0	0	0	0	112.4	K225 L226 K231 H232 S233 L472	K225-T229 WeakPolarHBondContact O-CB 3.42Å; K225-T229 PolarHBondContact O-N 3.41Å; K225-T229 PolarHBondContact O-OG1 2.81Å; L226-T229 PolarHBondContact O-N 2.96Å; L226-T229 VanDerWaalsContact O-N 3.16Å; T229-K231 VanDerWaalsContact C-N 3.31Å; T229-K231 PolarHBondContact O-N 2.82Å; T229-H232 PolarHBondContact O-N 3.5Å; T229-S233 PolarHBondContact O-N 3.47Å; T229-S233 PolarHBondContact O-OG 3.07Å; T229-L472 HydrophobicContact CG2-CD1 3.83Å; T229-L472 HydrophobicContact CG2-CD2 4Å
230	I	82.7	Confident	82.1	Confident	46 Å²	46	91.6 Å²	91.6	24%	0.236	45%	0.454	C	S	.	.	H	α-helix	trans	-63.6	-38.7	176.5	-67.2	170.2	0	0	0	110.8	L226 H232 S233 K234	L226-I230 HydrophobicContact CD1-CD1 3.85Å; L226-I230 HydrophobicContact CD1-CG1 4.04Å; L226-I230 HydrophobicContact CD2-CD1 4.43Å; L226-I230 HydrophobicContact CG-CD1 3.81Å; L226-I230 HydrophobicContact CG-CG1 4.39Å; L226-I230 WeakPolarHBondContact O-CG1 3.26Å; L226-I230 PolarHBondContact O-N 3.1Å; I230-H232 VanDerWaalsContact C-N 3.32Å; I230-H232 PolarHBondContact O-N 3.47Å; I230-S233 WeakPolarHBondContact CA-OG 3.25Å; I230-S233 PolarHBondContact O-N 2.83Å; I230-S233 PolarHBondContact O-OG 3.03Å; I230-S233 VanDerWaalsContact O-OG 3.07Å; I230-K234 WeakPolarHBondContact O-CG 3.47Å; I230-K234 PolarHBondContact O-N 3.1Å; I230-K234 VanDerWaalsContact O-N 3.12Å
231	K	85.6	Confident	81.5	Confident	151 Å²	151	95.2 Å²	95.2	66%	0.657	47%	0.467	S	S	*	.	H	α-helix	trans	-62.2	-41.1	175.9	-172.1	-179.3	178.1	-174.9	0	111.3	K227 T228 T229	K227-K231 WeakPolarHBondContact O-CB 3.32Å; K227-K231 PolarHBondContact O-N 2.68Å; T228-K231 PolarHBondContact O-N 3.5Å; T229-K231 VanDerWaalsContact C-N 3.31Å; T229-K231 PolarHBondContact O-N 2.82Å
232	H	79.8	Confident	80.7	Confident	105 Å²	105	95.3 Å²	95.3	49%	0.486	47%	0.466	S	S	.	.	H	α-helix	trans	-73.4	-37.2	177.1	-77.2	-70.7	0	0	0	113.5	T228 T229 I230 K234 L235 N236	T228-H232 PolarHBondContact O-CD2 3.34Å; T228-H232 PolarHBondContact O-N 2.9Å; T229-H232 PolarHBondContact O-N 3.5Å; I230-H232 VanDerWaalsContact C-N 3.32Å; I230-H232 PolarHBondContact O-N 3.47Å; H232-K234 VanDerWaalsContact C-N 3.34Å; H232-K234 PolarHBondContact O-N 3.29Å; H232-L235 WeakPolarHBondContact O-CB 3.25Å; H232-L235 PolarHBondContact O-N 2.89Å; H232-N236 PolarHBondContact O-N 3.36Å
233	S	77.6	Confident	80.2	Confident	59 Å²	59	97.5 Å²	97.5	41%	0.413	48%	0.481	S	S	.	.	H	α-helix	trans	-66.9	-36.1	178.4	65.2	0	0	0	0	112.4	T229 I230 L235 N236 G237	T229-S233 PolarHBondContact O-N 3.47Å; T229-S233 PolarHBondContact O-OG 3.07Å; I230-S233 WeakPolarHBondContact CA-OG 3.25Å; I230-S233 PolarHBondContact O-N 2.83Å; I230-S233 PolarHBondContact O-OG 3.03Å; I230-S233 VanDerWaalsContact O-OG 3.07Å; S233-L235 PolarHBondContact O-N 2.99Å; S233-N236 PolarHBondContact O-N 3.16Å; S233-G237 PolarHBondContact O-N 3.23Å
234	K	79.3	Confident	79.9	Confident	145 Å²	145	100.8 Å²	100.8	63%	0.63	49%	0.486	S	S	*	.	H	α-helix	trans	-59.7	-32.3	172.5	-75.5	-175.9	178.4	-167.8	0	112.9	I230 H232	I230-K234 WeakPolarHBondContact O-CG 3.47Å; I230-K234 PolarHBondContact O-N 3.1Å; I230-K234 VanDerWaalsContact O-N 3.12Å; H232-K234 VanDerWaalsContact C-N 3.34Å; H232-K234 PolarHBondContact O-N 3.29Å
235	L	78.4	Confident	79.6	Confident	128 Å²	128	95.4 Å²	95.4	67%	0.67	46%	0.464	S	S	*	.	H	α-helix	trans	-76.5	-33.6	177.5	-67.8	169.8	0	0	0	112.4	H232 S233	H232-L235 WeakPolarHBondContact O-CB 3.25Å; H232-L235 PolarHBondContact O-N 2.89Å; S233-L235 PolarHBondContact O-N 2.99Å
236	N	71.9	Confident	79.3	Confident	105 Å²	105	93.7 Å²	93.7	56%	0.561	46%	0.457	S	S	*	.	H	α-helix	trans	-91.3	-4.3	-172.8	-70.4	-1.5	0	0	0	114.2	H232 S233 Y238	H232-N236 PolarHBondContact O-N 3.36Å; S233-N236 PolarHBondContact O-N 3.16Å; N236-Y238 PolarHBondContact O-N 3.16Å
237	G	67.9	Low	79.3	Confident	63 Å²	63	94.8 Å²	94.8	65%	0.649	46%	0.462	S	S	*	.			trans	61.5	4.8	171	0	0	0	0	0	116.5	S233	S233-G237 PolarHBondContact O-N 3.23Å
238	Y	61.6	Low	79.4	Confident	158 Å²	158	87.4 Å²	87.4	62%	0.62	43%	0.431	S	S	*	.			trans	-98.1	109.4	-172.5	-159.7	-99.3	0	0	0	110.9	N236 D240	N236-Y238 PolarHBondContact O-N 3.16Å; Y238-D240 HydrophobicContact CD1-CB 4.14Å; Y238-D240 HydrophobicContact CE1-CB 3.97Å
239	Y	66.8	Low	79.6	Confident	238 Å²	238	85.1 Å²	85.1	93%	0.933	42%	0.415	S	S	*	.			trans	-91.7	96.9	172.4	-86.1	-87.2	0	0	0	109.9
240	D	79.4	Confident	80	Confident	59 Å²	59	84.1 Å²	84.1	32%	0.316	41%	0.409	S	S	.	.			trans	-93.3	128.7	167.6	-171.5	-1.6	0	0	0	110.3	Y238 Q242 S243 Y244	Y238-D240 HydrophobicContact CD1-CB 4.14Å; Y238-D240 HydrophobicContact CE1-CB 3.97Å; D240-Q242 PolarHBondContact O-N 3.3Å; D240-Q242 PolarHBondContact OD1-N 2.8Å; D240-S243 WeakPolarHBondContact O-CB 3.49Å; D240-S243 PolarHBondContact O-N 3.24Å; D240-Y244 PolarHBondContact O-N 3.47Å; D240-Y244 VanDerWaalsContact O-N 3.15Å
241	K	81	Confident	80.5	Confident	140 Å²	140	84.8 Å²	84.8	61%	0.609	41%	0.413	S	S	*	.	H	α-helix	trans	-58.4	-33.1	174.2	-174.9	177.7	-179.9	178.8	0	111.4	Y244 N245	K241-Y244 PolarHBondContact O-N 3.4Å; K241-N245 PolarHBondContact O-N 3.01Å; K241-N245 VanDerWaalsContact O-N 3.13Å; K241-N245 PolarHBondContact O-ND2 3.17Å
242	Q	77.4	Confident	80.8	Confident	62 Å²	62	77.6 Å²	77.6	29%	0.29	38%	0.382	S	S	.	.	H	α-helix	trans	-68.1	-44.2	178	-175.7	63.3	4.7	0	0	111.6	D240 Y244 N245 E246 F474	D240-Q242 PolarHBondContact O-N 3.3Å; D240-Q242 PolarHBondContact OD1-N 2.8Å; Q242-Y244 VanDerWaalsContact C-N 3.26Å; Q242-Y244 PolarHBondContact O-N 3.43Å; Q242-N245 PolarHBondContact O-N 3.4Å; Q242-N245 VanDerWaalsContact O-N 3.16Å; Q242-E246 PolarHBondContact O-N 3.03Å; Q242-F474 PolarHBondContact NE2-O 3.14Å
243	S	80.3	Confident	81.5	Confident	46 Å²	46	72.7 Å²	72.7	32%	0.322	36%	0.359	S	S	.	.	H	α-helix	trans	-59.1	-38.1	174	-68	0	0	0	0	112.1	D240 L247 L472	D240-S243 WeakPolarHBondContact O-CB 3.49Å; D240-S243 PolarHBondContact O-N 3.24Å; S243-L247 VanDerWaalsContact O-CB 3.22Å; S243-L247 WeakPolarHBondContact O-CB 3.44Å; S243-L247 PolarHBondContact O-N 2.81Å; S243-L472 PolarHBondContact OG-O 3.32Å
244	Y	84.9	Confident	82.3	Confident	120 Å²	120	71.2 Å²	71.2	47%	0.471	35%	0.346	S	S	.	.	H	α-helix	trans	-64.2	-43.3	175.2	-178.1	-103.5	0	0	0	112.4	D240 K241 Q242 E246 L247 S248 P320	D240-Y244 PolarHBondContact O-N 3.47Å; D240-Y244 VanDerWaalsContact O-N 3.15Å; K241-Y244 PolarHBondContact O-N 3.4Å; Q242-Y244 VanDerWaalsContact C-N 3.26Å; Q242-Y244 PolarHBondContact O-N 3.43Å; Y244-E246 PolarHBondContact O-N 3.32Å; Y244-L247 PolarHBondContact O-N 3.49Å; Y244-S248 WeakPolarHBondContact O-CB 3.41Å; Y244-S248 PolarHBondContact O-N 2.88Å; Y244-S248 PolarHBondContact O-OG 2.78Å; Y244-P320 HydrophobicContact CE1-CG 3.73Å
245	N	84.7	Confident	83	Confident	21 Å²	21	65.3 Å²	65.3	11%	0.112	32%	0.324	C	S	.	.	H	α-helix	trans	-64.2	-41.1	177.9	-72.8	-27.1	0	0	0	112.6	K241 Q242 S248 K249 I321	K241-N245 PolarHBondContact O-N 3.01Å; K241-N245 VanDerWaalsContact O-N 3.13Å; K241-N245 PolarHBondContact O-ND2 3.17Å; Q242-N245 PolarHBondContact O-N 3.4Å; Q242-N245 VanDerWaalsContact O-N 3.16Å; N245-S248 WeakPolarHBondContact O-CB 3.32Å; N245-S248 PolarHBondContact O-N 3.25Å; N245-K249 WeakPolarHBondContact O-CG 3.09Å; N245-K249 PolarHBondContact O-N 3.34Å; N245-K249 VanDerWaalsContact O-N 3.12Å; N245-I321 HydrophobicContact CB-CD1 3.89Å
246	E	82.9	Confident	83.8	Confident	28 Å²	28	59.5 Å²	59.5	13%	0.131	29%	0.294	C	S	.	.	H	α-helix	trans	-68.6	-39.7	175.8	-67.9	-55.1	131.9	0	0	111.9	Q242 Y244 S248 K249 V250 F474	Q242-E246 PolarHBondContact O-N 3.03Å; Y244-E246 PolarHBondContact O-N 3.32Å; E246-S248 VanDerWaalsContact C-N 3.33Å; E246-S248 PolarHBondContact O-N 3.44Å; E246-K249 WeakPolarHBondContact O-CB 3.09Å; E246-K249 PolarHBondContact O-N 3.18Å; E246-K249 IonicContact OE1-NZ 3.84Å; E246-K249 PolarHBondContact OE1-NZ 2.96Å; E246-K249 IonicContact OE2-NZ 2.64Å; E246-V250 WeakPolarHBondContact O-CG2 3.07Å; E246-V250 PolarHBondContact O-N 2.91Å; E246-V250 VanDerWaalsContact O-N 3.09Å; E246-F474 HydrophobicContact CB-CD2 4.01Å; E246-F474 HydrophobicContact CG-CB 3.94Å; E246-F474 HydrophobicContact CG-CD2 3.88Å; E246-F474 HydrophobicContact CG-CG 4.24Å
247	L	87	Confident	84.9	Confident	53 Å²	53	54.5 Å²	54.5	28%	0.277	27%	0.267	S	S	.	.	H	α-helix	trans	-58.9	-45	172.3	175.2	60.5	0	0	0	111.3	L226 S243 Y244 K249 V250 I251	L226-L247 HydrophobicContact CD1-CD1 3.24Å; L226-L247 HydrophobicContact CD2-CD1 4.38Å; L226-L247 HydrophobicContact CG-CD1 4.41Å; S243-L247 VanDerWaalsContact O-CB 3.22Å; S243-L247 WeakPolarHBondContact O-CB 3.44Å; S243-L247 PolarHBondContact O-N 2.81Å; Y244-L247 PolarHBondContact O-N 3.49Å; L247-K249 VanDerWaalsContact C-N 3.3Å; L247-K249 PolarHBondContact O-N 3.16Å; L247-V250 PolarHBondContact O-N 3.02Å; L247-V250 VanDerWaalsContact O-N 3.12Å; L247-I251 HydrophobicContact CD1-CD1 3.94Å; L247-I251 HydrophobicContact CD1-CG1 4.09Å; L247-I251 HydrophobicContact CD2-CD1 4.38Å; L247-I251 HydrophobicContact CG-CD1 3.77Å; L247-I251 HydrophobicContact CG-CG1 4.35Å; L247-I251 WeakPolarHBondContact O-CG1 3.48Å; L247-I251 PolarHBondContact O-N 2.84Å
248	S	89.8	Confident	86.1	Confident	6 Å²	6	55.5 Å²	55.5	4%	0.042	26%	0.257	C	S	.	.	H	α-helix	trans	-57.1	-40.6	174.7	-81.5	0	0	0	0	112.5	Y244 N245 E246 I251 T252 F318 P320	Y244-S248 WeakPolarHBondContact O-CB 3.41Å; Y244-S248 PolarHBondContact O-N 2.88Å; Y244-S248 PolarHBondContact O-OG 2.78Å; N245-S248 WeakPolarHBondContact O-CB 3.32Å; N245-S248 PolarHBondContact O-N 3.25Å; E246-S248 VanDerWaalsContact C-N 3.33Å; E246-S248 PolarHBondContact O-N 3.44Å; S248-I251 PolarHBondContact O-N 2.95Å; S248-T252 WeakPolarHBondContact O-CB 3.43Å; S248-T252 PolarHBondContact O-N 3.27Å; S248-T252 PolarHBondContact O-OG1 3.22Å; S248-F318 VanDerWaalsContact CB-O 3.26Å; S248-F318 WeakPolarHBondContact CB-O 3.3Å; S248-F318 PolarHBondContact OG-O 3.38Å; S248-P320 WeakPolarHBondContact OG-CD 3.49Å
249	K	90.5	Very high	87.7	Confident	19 Å²	19	49.5 Å²	49.5	8%	0.083	24%	0.235	C	C	.	.	H	α-helix	trans	-62.5	-42.7	174.7	-70	173	-173	169.7	0	111.9	F59 N245 E246 L247 T252 H253 L319	F59-K249 HydrophobicContact CB-CD 4.42Å; F59-K249 HydrophobicContact CD2-CB 3.77Å; F59-K249 HydrophobicContact CD2-CD 4.08Å; F59-K249 HydrophobicContact CD2-CG 3.9Å; F59-K249 HydrophobicContact CE2-CB 3.65Å; F59-K249 HydrophobicContact CE2-CG 3.93Å; F59-K249 HydrophobicContact CG-CD 4.13Å; F59-K249 HydrophobicContact CG-CG 4.25Å; F59-K249 HydrophobicContact CZ-CB 4.38Å; F59-K249 HydrophobicContact CZ-CG 4.28Å; N245-K249 WeakPolarHBondContact O-CG 3.09Å; N245-K249 PolarHBondContact O-N 3.34Å; N245-K249 VanDerWaalsContact O-N 3.12Å; E246-K249 WeakPolarHBondContact O-CB 3.09Å; E246-K249 PolarHBondContact O-N 3.18Å; E246-K249 IonicContact OE1-NZ 3.84Å; E246-K249 PolarHBondContact OE1-NZ 2.96Å; E246-K249 IonicContact OE2-NZ 2.64Å; L247-K249 VanDerWaalsContact C-N 3.3Å; L247-K249 PolarHBondContact O-N 3.16Å; K249-T252 PolarHBondContact O-N 2.91Å; K249-H253 WeakPolarHBondContact O-CB 3.39Å; K249-H253 PolarHBondContact O-N 3.28Å; K249-L319 HydrophobicContact CG-CD1 3.67Å
250	V	90.8	Very high	89	Confident	14 Å²	14	39.3 Å²	39.3	9%	0.085	20%	0.195	C	C	.	.	H	α-helix	trans	-65.4	-44.5	177.2	176.8	0	0	0	0	111.1	I137 I222 E246 L247 H253 L254	I137-V250 HydrophobicContact CD1-CG1 4Å; I137-V250 HydrophobicContact CD1-CG2 3.96Å; I137-V250 HydrophobicContact CG1-CG2 4.4Å; I222-V250 HydrophobicContact CG2-CG1 3.51Å; E246-V250 WeakPolarHBondContact O-CG2 3.07Å; E246-V250 PolarHBondContact O-N 2.91Å; E246-V250 VanDerWaalsContact O-N 3.09Å; L247-V250 PolarHBondContact O-N 3.02Å; L247-V250 VanDerWaalsContact O-N 3.12Å; V250-H253 PolarHBondContact O-N 3Å; V250-L254 WeakPolarHBondContact O-CB 3.47Å; V250-L254 PolarHBondContact O-N 3.28Å
251	I	92.1	Very high	89.6	Confident	61 Å²	61	37.7 Å²	37.7	31%	0.313	19%	0.188	S	C	.	.	H	α-helix	trans	-62.2	-43.5	176.4	-68.1	170.4	0	0	0	110.7	L247 S248 H253 L254 A255 F318	L247-I251 HydrophobicContact CD1-CD1 3.94Å; L247-I251 HydrophobicContact CD1-CG1 4.09Å; L247-I251 HydrophobicContact CD2-CD1 4.38Å; L247-I251 HydrophobicContact CG-CD1 3.77Å; L247-I251 HydrophobicContact CG-CG1 4.35Å; L247-I251 WeakPolarHBondContact O-CG1 3.48Å; L247-I251 PolarHBondContact O-N 2.84Å; S248-I251 PolarHBondContact O-N 2.95Å; I251-H253 PolarHBondContact O-N 2.94Å; I251-L254 PolarHBondContact O-N 2.87Å; I251-A255 WeakPolarHBondContact O-CB 3.21Å; I251-A255 PolarHBondContact O-N 3.21Å; I251-F318 HydrophobicContact CG2-CB 4.47Å; I251-F318 HydrophobicContact CG2-CD1 3.74Å; I251-F318 HydrophobicContact CG2-CE1 4.25Å; I251-F318 HydrophobicContact CG2-CG 4.21Å
252	T	93.7	Very high	90.1	Very high	0 Å²	0	35 Å²	35	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-60.8	-46.9	178	-54.4	0	0	0	0	110.8	S248 K249 L254 A255 I256 Y315 F318	S248-T252 WeakPolarHBondContact O-CB 3.43Å; S248-T252 PolarHBondContact O-N 3.27Å; S248-T252 PolarHBondContact O-OG1 3.22Å; K249-T252 PolarHBondContact O-N 2.91Å; T252-L254 VanDerWaalsContact C-N 3.34Å; T252-L254 PolarHBondContact O-N 2.95Å; T252-A255 PolarHBondContact O-N 3.4Å; T252-I256 HydrophobicContact CG2-CD1 4.01Å; T252-I256 WeakPolarHBondContact O-CG1 3.43Å; T252-I256 PolarHBondContact O-N 3.18Å; T252-Y315 HydrophobicContact CG2-CD1 3.64Å; T252-Y315 HydrophobicContact CG2-CE1 3.97Å; T252-F318 HydrophobicContact CG2-CB 4.36Å; T252-F318 WeakPolarHBondContact OG1-CB 3.45Å
253	H	93.4	Very high	90.8	Very high	1 Å²	1	34.2 Å²	34.2	1%	0.005	18%	0.183	C	C	.	.	H	α-helix	trans	-60.4	-42.9	175.7	175.8	-84	0	0	0	112.1	F129 S130 R133 K249 V250 I251 A255 I256 S257	F129-H253 AromaticContact CD1-CD2 3.69Å; F129-H253 AromaticContact CD2-CD2 3.85Å; F129-H253 AromaticContact CE1-CD2 3.99Å; F129-H253 AromaticContact CG-CD2 3.62Å; F129-H253 AromaticContact CG-NE2 3.96Å; S130-H253 VanDerWaalsContact CA-CE1 3.48Å; S130-H253 WeakPolarHBondContact CA-CE1 3.38Å; S130-H253 VanDerWaalsContact CA-NE2 3.34Å; S130-H253 WeakPolarHBondContact CA-NE2 3.49Å; S130-H253 PolarHBondContact N-NE2 3.31Å; S130-H253 PolarHBondContact OG-CE1 3.05Å; S130-H253 PolarHBondContact OG-NE2 3.25Å; S130-H253 VanDerWaalsContact OG-NE2 3.15Å; R133-H253 HydrophobicContact CG-CB 4.31Å; K249-H253 WeakPolarHBondContact O-CB 3.39Å; K249-H253 PolarHBondContact O-N 3.28Å; V250-H253 PolarHBondContact O-N 3Å; I251-H253 PolarHBondContact O-N 2.94Å; H253-A255 VanDerWaalsContact C-N 3.32Å; H253-A255 PolarHBondContact O-N 2.8Å; H253-I256 PolarHBondContact O-N 3.48Å; H253-S257 WeakPolarHBondContact O-CB 3.44Å; H253-S257 PolarHBondContact O-N 3.26Å; H253-S257 PolarHBondContact O-OG 3.34Å
254	L	94	Very high	91.3	Very high	29 Å²	29	32.2 Å²	32.2	15%	0.152	17%	0.169	C	C	.	.	H	α-helix	trans	-62	-41.1	176.1	-172.3	68.9	0	0	0	111.2	N219 V250 I251 T252 S257 I258	N219-L254 HydrophobicContact CB-CD1 4Å; V250-L254 WeakPolarHBondContact O-CB 3.47Å; V250-L254 PolarHBondContact O-N 3.28Å; I251-L254 PolarHBondContact O-N 2.87Å; T252-L254 VanDerWaalsContact C-N 3.34Å; T252-L254 PolarHBondContact O-N 2.95Å; L254-S257 WeakPolarHBondContact CA-OG 3.15Å; L254-S257 PolarHBondContact O-OG 3.35Å; L254-I258 HydrophobicContact CD1-CD1 4.23Å; L254-I258 HydrophobicContact CD1-CG1 4.49Å; L254-I258 HydrophobicContact CD2-CD1 4.4Å; L254-I258 HydrophobicContact CG-CD1 3.81Å; L254-I258 HydrophobicContact CG-CG1 4.44Å; L254-I258 WeakPolarHBondContact O-CB 3.3Å; L254-I258 WeakPolarHBondContact O-CG1 3.38Å; L254-I258 PolarHBondContact O-N 3.03Å
255	A	95.1	Very high	91.5	Very high	21 Å²	21	31.2 Å²	31.2	17%	0.174	17%	0.172	C	C	.	.	H	α-helix	trans	-64.1	-46.6	177.3	0	0	0	0	0	112.2	I251 T252 H253 S257 I258 M259 L314 F318	I251-A255 WeakPolarHBondContact O-CB 3.21Å; I251-A255 PolarHBondContact O-N 3.21Å; T252-A255 PolarHBondContact O-N 3.4Å; H253-A255 VanDerWaalsContact C-N 3.32Å; H253-A255 PolarHBondContact O-N 2.8Å; A255-S257 PolarHBondContact O-N 3.26Å; A255-I258 PolarHBondContact O-N 3.03Å; A255-M259 WeakPolarHBondContact O-CB 3.42Å; A255-M259 PolarHBondContact O-N 2.9Å; A255-L314 HydrophobicContact CB-CD2 4.25Å; A255-F318 HydrophobicContact CB-CD2 3.83Å; A255-F318 HydrophobicContact CB-CE2 3.62Å; A255-F318 HydrophobicContact CB-CZ 4.34Å
256	I	95.4	Very high	91.8	Very high	5 Å²	5	32.3 Å²	32.3	3%	0.026	18%	0.179	C	C	.	.	H	α-helix	trans	-59.7	-47.5	177.2	-67.2	166.1	0	0	0	110.5	L126 T252 H253 M259 F260 L314 Y315	L126-I256 HydrophobicContact CD1-CG2 3.96Å; T252-I256 HydrophobicContact CG2-CD1 4.01Å; T252-I256 WeakPolarHBondContact O-CG1 3.43Å; T252-I256 PolarHBondContact O-N 3.18Å; H253-I256 PolarHBondContact O-N 3.48Å; I256-M259 PolarHBondContact O-N 3.01Å; I256-F260 WeakPolarHBondContact O-CB 3.42Å; I256-F260 PolarHBondContact O-N 3.06Å; I256-L314 HydrophobicContact CB-CD1 4.27Å; I256-L314 HydrophobicContact CG1-CB 4.15Å; I256-L314 HydrophobicContact CG1-CD1 3.62Å; I256-Y315 HydrophobicContact CD1-CD1 4.45Å; I256-Y315 HydrophobicContact CD1-CE1 3.71Å; I256-Y315 HydrophobicContact CD1-CE2 4.37Å
257	S	94.3	Very high	92.2	Very high	0 Å²	0	31 Å²	31	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-70.4	-33.1	-178.1	56	0	0	0	0	113.8	N219 H253 L254 A255 T261	N219-S257 WeakPolarHBondContact ND2-CB 3.33Å; N219-S257 PolarHBondContact ND2-OG 2.59Å; N219-S257 PolarHBondContact OD1-OG 2.98Å; H253-S257 WeakPolarHBondContact O-CB 3.44Å; H253-S257 PolarHBondContact O-N 3.26Å; H253-S257 PolarHBondContact O-OG 3.34Å; L254-S257 WeakPolarHBondContact CA-OG 3.15Å; L254-S257 PolarHBondContact O-OG 3.35Å; A255-S257 PolarHBondContact O-N 3.26Å; S257-T261 WeakPolarHBondContact O-CB 3.23Å; S257-T261 PolarHBondContact O-N 3.47Å; S257-T261 PolarHBondContact O-OG1 2.89Å
258	I	93.9	Very high	92.2	Very high	84 Å²	84	29.3 Å²	29.3	43%	0.431	17%	0.165	S	C	.	.	H	α-helix	trans	-65	-46.9	170.6	-72.3	168.3	0	0	0	110	L254 A255 F260 T261 C262	L254-I258 HydrophobicContact CD1-CD1 4.23Å; L254-I258 HydrophobicContact CD1-CG1 4.49Å; L254-I258 HydrophobicContact CD2-CD1 4.4Å; L254-I258 HydrophobicContact CG-CD1 3.81Å; L254-I258 HydrophobicContact CG-CG1 4.44Å; L254-I258 WeakPolarHBondContact O-CB 3.3Å; L254-I258 WeakPolarHBondContact O-CG1 3.38Å; L254-I258 PolarHBondContact O-N 3.03Å; A255-I258 PolarHBondContact O-N 3.03Å; I258-F260 PolarHBondContact O-N 3.36Å; I258-T261 PolarHBondContact O-N 2.92Å; I258-C262 WeakPolarHBondContact O-CB 3.42Å; I258-C262 PolarHBondContact O-N 2.85Å; I258-C262 PolarHBondContact O-SG 3.42Å
259	M	94.5	Very high	92.2	Very high	33 Å²	33	32.4 Å²	32.4	16%	0.163	18%	0.184	C	C	.	.	H	α-helix	trans	-58.3	-49	177.7	-174.8	-174.5	65.8	0	0	111	A255 I256 T261 C262 L263 N307 F310 L314	A255-M259 WeakPolarHBondContact O-CB 3.42Å; A255-M259 PolarHBondContact O-N 2.9Å; I256-M259 PolarHBondContact O-N 3.01Å; M259-T261 PolarHBondContact O-N 3.21Å; M259-C262 PolarHBondContact O-N 2.95Å; M259-L263 HydrophobicContact CG-CD1 4.24Å; M259-L263 PolarHBondContact O-N 3.28Å; M259-N307 HydrophobicContact CE-CB 4.41Å; M259-N307 WeakPolarHBondContact CE-O 3.33Å; M259-N307 PolarHBondContact O-OD1 3.26Å; M259-F310 HydrophobicContact CE-CB 4.2Å; M259-F310 HydrophobicContact SD-CB 3.62Å; M259-F310 HydrophobicContact SD-CD2 4.34Å; M259-F310 HydrophobicContact SD-CG 4.46Å; M259-L314 HydrophobicContact CB-CD1 4.44Å; M259-L314 HydrophobicContact CE-CD1 3.65Å; M259-L314 HydrophobicContact SD-CD1 3.82Å
260	F	93.2	Very high	92.3	Very high	23 Å²	23	32.5 Å²	32.5	10%	0.101	19%	0.185	C	C	.	.	H	α-helix	trans	-53.4	-53.7	174	177.3	-98.3	0	0	0	111.1	L126 I215 I256 I258 C262 L263 S264 N307	L126-F260 HydrophobicContact CD2-CB 3.79Å; L126-F260 HydrophobicContact CD2-CD1 3.77Å; L126-F260 HydrophobicContact CD2-CD2 3.83Å; L126-F260 HydrophobicContact CD2-CE1 4.31Å; L126-F260 HydrophobicContact CD2-CE2 4.36Å; L126-F260 HydrophobicContact CD2-CG 3.5Å; L126-F260 VanDerWaalsContact CD2-CG 3.5Å; I215-F260 HydrophobicContact CD1-CD1 3.76Å; I215-F260 HydrophobicContact CD1-CE1 3.63Å; I256-F260 WeakPolarHBondContact O-CB 3.42Å; I256-F260 PolarHBondContact O-N 3.06Å; I258-F260 PolarHBondContact O-N 3.36Å; F260-C262 VanDerWaalsContact C-N 3.34Å; F260-C262 PolarHBondContact O-N 3.05Å; F260-L263 PolarHBondContact O-N 3.03Å; F260-S264 WeakPolarHBondContact CE2-OG 3.36Å; F260-S264 WeakPolarHBondContact O-CB 3.45Å; F260-S264 PolarHBondContact O-N 2.99Å; F260-S264 PolarHBondContact O-OG 3.41Å; F260-N307 WeakPolarHBondContact CA-OD1 3.38Å; F260-N307 PolarHBondContact N-OD1 2.95Å
261	T	92.1	Very high	92.1	Very high	26 Å²	26	32.6 Å²	32.6	16%	0.16	19%	0.185	C	C	.	.	H	α-helix	trans	-61	-42	-178.6	-53.4	0	0	0	0	112.2	S257 I258 M259 L263 L265	S257-T261 WeakPolarHBondContact O-CB 3.23Å; S257-T261 PolarHBondContact O-N 3.47Å; S257-T261 PolarHBondContact O-OG1 2.89Å; I258-T261 PolarHBondContact O-N 2.92Å; M259-T261 PolarHBondContact O-N 3.21Å; T261-L263 PolarHBondContact O-N 3.44Å; T261-L265 WeakPolarHBondContact O-CB 3.47Å; T261-L265 PolarHBondContact O-N 2.73Å
262	C	92.9	Very high	91.9	Very high	83 Å²	83	33.3 Å²	33.3	56%	0.561	19%	0.189	S	C	*	.	H	α-helix	trans	-64.5	-37.5	-179.8	-74.1	0	0	0	0	112.8	I258 M259 F260 P266	I258-C262 WeakPolarHBondContact O-CB 3.42Å; I258-C262 PolarHBondContact O-N 2.85Å; I258-C262 PolarHBondContact O-SG 3.42Å; M259-C262 PolarHBondContact O-N 2.95Å; F260-C262 VanDerWaalsContact C-N 3.34Å; F260-C262 PolarHBondContact O-N 3.05Å; C262-P266 WeakPolarHBondContact O-CD 3.31Å
263	L	92.3	Very high	91.8	Very high	45 Å²	45	36 Å²	36	24%	0.236	20%	0.202	C	C	.	.	H	α-helix	trans	-86.4	-36.2	-179.7	-70.9	179.2	0	0	0	112.6	M259 F260 T261 I303 F306 N307	M259-L263 HydrophobicContact CG-CD1 4.24Å; M259-L263 PolarHBondContact O-N 3.28Å; F260-L263 PolarHBondContact O-N 3.03Å; T261-L263 PolarHBondContact O-N 3.44Å; L263-I303 HydrophobicContact CD2-CG2 4.01Å; L263-F306 HydrophobicContact CD1-CB 3.73Å; L263-N307 WeakPolarHBondContact CB-ND2 3.42Å; L263-N307 WeakPolarHBondContact CD1-OD1 3.43Å
264	S	89	Confident	91.5	Very high	5 Å²	5	39.5 Å²	39.5	4%	0.035	22%	0.216	C	C	.	.	H	α-helix	trans	-77	-29.9	-179.5	-55.3	0	0	0	0	112.8	F260 L267 V268	F260-S264 WeakPolarHBondContact CE2-OG 3.36Å; F260-S264 WeakPolarHBondContact O-CB 3.45Å; F260-S264 PolarHBondContact O-N 2.99Å; F260-S264 PolarHBondContact O-OG 3.41Å; S264-L267 WeakPolarHBondContact O-CB 3.11Å; S264-L267 PolarHBondContact O-N 3.5Å; S264-V268 WeakPolarHBondContact O-CG2 3.17Å; S264-V268 PolarHBondContact O-N 3.14Å
265	L	89.7	Confident	91.1	Very high	99 Å²	99	39.2 Å²	39.2	52%	0.518	21%	0.214	S	C	.	.	H	α-helix	trans	-61	-50.2	-179.1	-176.9	162.3	0	0	0	112.9	T261 L267 V268 V269	T261-L265 WeakPolarHBondContact O-CB 3.47Å; T261-L265 PolarHBondContact O-N 2.73Å; L265-L267 VanDerWaalsContact C-N 3.27Å; L265-L267 PolarHBondContact O-N 3.47Å; L265-V268 WeakPolarHBondContact O-CB 3.34Å; L265-V268 PolarHBondContact O-N 2.87Å; L265-V269 HydrophobicContact CD2-CG2 4.1Å; L265-V269 WeakPolarHBondContact O-CG2 3.34Å; L265-V269 PolarHBondContact O-N 3.08Å
266	P	91.7	Very high	90.8	Very high	43 Å²	43	43.9 Å²	43.9	28%	0.279	23%	0.23	S	C	.	.	H	α-helix	trans	-57.2	-40	173.7	-26.2	35.2	0	0	0	112.9	C262 V269 I270 F300	C262-P266 WeakPolarHBondContact O-CD 3.31Å; P266-V269 PolarHBondContact O-N 3.49Å; P266-I270 WeakPolarHBondContact O-CG1 3.33Å; P266-I270 PolarHBondContact O-N 3.3Å; P266-F300 HydrophobicContact CB-CD1 3.69Å; P266-F300 HydrophobicContact CB-CE1 3.38Å; P266-F300 HydrophobicContact CB-CZ 4.06Å; P266-F300 HydrophobicContact CG-CE1 4.3Å
267	L	90.4	Very high	90.4	Very high	2 Å²	2	43.7 Å²	43.7	1%	0.01	23%	0.229	C	C	.	.	H	α-helix	trans	-61.5	-45	176	178.6	61.7	0	0	0	111.4	S264 L265 V269 I270 M271 F300 D304	S264-L267 WeakPolarHBondContact O-CB 3.11Å; S264-L267 PolarHBondContact O-N 3.5Å; L265-L267 VanDerWaalsContact C-N 3.27Å; L265-L267 PolarHBondContact O-N 3.47Å; L267-V269 PolarHBondContact O-N 2.81Å; L267-I270 PolarHBondContact O-N 2.03Å; L267-M271 HydrophobicContact CD1-CE 3.67Å; L267-M271 HydrophobicContact CD1-CG 4.25Å; L267-M271 HydrophobicContact CG-CG 4.5Å; L267-M271 WeakPolarHBondContact O-CB 3.27Å; L267-M271 VanDerWaalsContact O-CG 3.31Å; L267-M271 WeakPolarHBondContact O-CG 3.42Å; L267-M271 PolarHBondContact O-N 3.08Å; L267-F300 HydrophobicContact CB-CB 4.31Å; L267-F300 HydrophobicContact CD1-CB 3.86Å; L267-D304 HydrophobicContact CD2-CB 4.2Å
268	V	86.5	Confident	89.9	Confident	17 Å²	17	46.9 Å²	46.9	10%	0.103	24%	0.244	C	C	.	.	H	α-helix	trans	-58	-49.7	176.5	179.3	0	0	0	0	110.6	T208 I209 S264 L265 I270 M271 I272	T208-V268 HydrophobicContact CG2-CG2 4.4Å; I209-V268 HydrophobicContact CG1-CG1 4.07Å; S264-V268 WeakPolarHBondContact O-CG2 3.17Å; S264-V268 PolarHBondContact O-N 3.14Å; L265-V268 WeakPolarHBondContact O-CB 3.34Å; L265-V268 PolarHBondContact O-N 2.87Å; V268-I270 VanDerWaalsContact C-N 3.32Å; V268-I270 PolarHBondContact O-N 3.11Å; V268-M271 PolarHBondContact O-N 2.88Å; V268-I272 HydrophobicContact CG1-CD1 3.81Å; V268-I272 HydrophobicContact CG1-CG1 4.45Å; V268-I272 WeakPolarHBondContact O-CG1 3.42Å; V268-I272 PolarHBondContact O-N 2.89Å
269	V	91.3	Very high	89.5	Confident	71 Å²	71	48 Å²	48	43%	0.43	25%	0.246	S	C	.	.	H	α-helix	trans	-59.2	-46.1	-178.9	173.1	0	0	0	0	110.5	L265 P266 L267 I272 L273	L265-V269 HydrophobicContact CD2-CG2 4.1Å; L265-V269 WeakPolarHBondContact O-CG2 3.34Å; L265-V269 PolarHBondContact O-N 3.08Å; P266-V269 PolarHBondContact O-N 3.49Å; L267-V269 PolarHBondContact O-N 2.81Å; V269-I272 PolarHBondContact O-N 2.85Å; V269-L273 HydrophobicContact CG1-CD1 4.13Å; V269-L273 WeakPolarHBondContact O-CG 3.49Å; V269-L273 PolarHBondContact O-N 3.37Å
270	I	92	Very high	89.2	Confident	21 Å²	21	49.7 Å²	49.7	11%	0.108	26%	0.256	C	S	.	.	H	α-helix	trans	-68.3	-35.6	179.2	-65.2	-68.1	0	0	0	111.8	P266 L267 V268 L273 R274 L296 S297 F300	P266-I270 WeakPolarHBondContact O-CG1 3.33Å; P266-I270 PolarHBondContact O-N 3.3Å; L267-I270 PolarHBondContact O-N 2.03Å; V268-I270 VanDerWaalsContact C-N 3.32Å; V268-I270 PolarHBondContact O-N 3.11Å; I270-L273 HydrophobicContact CD1-CD1 4.26Å; I270-L273 PolarHBondContact O-N 2.89Å; I270-R274 WeakPolarHBondContact O-CB 3.48Å; I270-R274 PolarHBondContact O-N 2.88Å; I270-L296 HydrophobicContact CD1-CB 4.48Å; I270-L296 HydrophobicContact CG2-CB 4.32Å; I270-S297 VanDerWaalsContact CG2-CA 3.44Å; I270-F300 HydrophobicContact CG1-CD2 3.91Å; I270-F300 HydrophobicContact CG1-CE2 4.11Å
271	M	86.5	Confident	88.9	Confident	15 Å²	15	53.4 Å²	53.4	7%	0.074	28%	0.277	C	S	.	.	H	α-helix	trans	-64.5	-42.5	174.4	-75.8	-57.4	137.8	0	0	112.4	I204 L267 V268 L273 R274 Q275 S297	I204-M271 HydrophobicContact CD1-CB 4.26Å; I204-M271 HydrophobicContact CG1-CB 4.16Å; L267-M271 HydrophobicContact CD1-CE 3.67Å; L267-M271 HydrophobicContact CD1-CG 4.25Å; L267-M271 HydrophobicContact CG-CG 4.5Å; L267-M271 WeakPolarHBondContact O-CB 3.27Å; L267-M271 VanDerWaalsContact O-CG 3.31Å; L267-M271 WeakPolarHBondContact O-CG 3.42Å; L267-M271 PolarHBondContact O-N 3.08Å; V268-M271 PolarHBondContact O-N 2.88Å; M271-L273 VanDerWaalsContact C-N 3.35Å; M271-R274 PolarHBondContact O-N 3.41Å; M271-Q275 PolarHBondContact O-N 3Å; M271-S297 VanDerWaalsContact CE-CB 3.46Å
272	I	88	Confident	88.7	Confident	77 Å²	77	55.3 Å²	55.3	40%	0.395	28%	0.281	S	S	.	.	H	α-helix	trans	-63.4	-43.3	175.1	-66.7	168.4	0	0	0	110.3	I209 V268 V269 R274 Q275 K276	I209-I272 HydrophobicContact CD1-CD1 4.46Å; V268-I272 HydrophobicContact CG1-CD1 3.81Å; V268-I272 HydrophobicContact CG1-CG1 4.45Å; V268-I272 WeakPolarHBondContact O-CG1 3.42Å; V268-I272 PolarHBondContact O-N 2.89Å; V269-I272 PolarHBondContact O-N 2.85Å; I272-R274 VanDerWaalsContact C-N 3.34Å; I272-R274 PolarHBondContact O-N 3.29Å; I272-Q275 PolarHBondContact O-N 2.95Å; I272-K276 PolarHBondContact O-N 3.21Å
273	L	91.2	Very high	88.4	Confident	56 Å²	56	56 Å²	56	29%	0.293	28%	0.276	S	S	.	.	H	α-helix	trans	-61.8	-42.5	175.3	-73.4	172.1	0	0	0	111.7	V269 I270 M271 Q275 K276 V277 I293	V269-L273 HydrophobicContact CG1-CD1 4.13Å; V269-L273 WeakPolarHBondContact O-CG 3.49Å; V269-L273 PolarHBondContact O-N 3.37Å; I270-L273 HydrophobicContact CD1-CD1 4.26Å; I270-L273 PolarHBondContact O-N 2.89Å; M271-L273 VanDerWaalsContact C-N 3.35Å; L273-Q275 VanDerWaalsContact C-N 3.34Å; L273-Q275 PolarHBondContact O-N 3.16Å; L273-K276 WeakPolarHBondContact O-CB 3.45Å; L273-K276 PolarHBondContact O-N 3.32Å; L273-V277 VanDerWaalsContact O-CG2 3.29Å; L273-V277 WeakPolarHBondContact O-CG2 3.36Å; L273-V277 PolarHBondContact O-N 3.38Å; L273-I293 HydrophobicContact CB-CG2 4.33Å
274	R	88.6	Confident	88.3	Confident	74 Å²	74	61 Å²	61	28%	0.279	30%	0.302	S	S	.	.	H	α-helix	trans	-61	-42.2	175.4	-178	173.5	175.1	-171.5	-7	111.7	I270 M271 I272 V277 H278 I293 S297	I270-R274 WeakPolarHBondContact O-CB 3.48Å; I270-R274 PolarHBondContact O-N 2.88Å; M271-R274 PolarHBondContact O-N 3.41Å; I272-R274 VanDerWaalsContact C-N 3.34Å; I272-R274 PolarHBondContact O-N 3.29Å; R274-V277 WeakPolarHBondContact O-CB 3.05Å; R274-V277 PolarHBondContact O-N 3.12Å; R274-H278 PolarHBondContact O-CD2 3.46Å; R274-H278 PolarHBondContact O-N 3.1Å; R274-H278 VanDerWaalsContact O-N 3.1Å; R274-I293 HydrophobicContact CB-CG2 3.83Å; R274-S297 WeakPolarHBondContact CD-OG 3.48Å; R274-S297 PolarHBondContact NH1-OG 3.02Å
275	Q	84.6	Confident	88.4	Confident	24 Å²	24	66 Å²	66	11%	0.112	33%	0.328	C	S	.	.	H	α-helix	trans	-61.3	-46.9	173.3	-76.4	-164	-37.6	0	0	111.8	L200 I204 M271 I272 L273 V277 H278 F279	L200-Q275 HydrophobicContact CD2-CG 4Å; L200-Q275 HydrophobicContact CG-CG 4.48Å; I204-Q275 HydrophobicContact CD1-CG 3.53Å; M271-Q275 PolarHBondContact O-N 3Å; I272-Q275 PolarHBondContact O-N 2.95Å; L273-Q275 VanDerWaalsContact C-N 3.34Å; L273-Q275 PolarHBondContact O-N 3.16Å; Q275-V277 PolarHBondContact O-N 3.06Å; Q275-H278 PolarHBondContact O-N 3.09Å; Q275-H278 VanDerWaalsContact O-N 3.07Å; Q275-F279 HydrophobicContact CB-CD2 4.2Å; Q275-F279 HydrophobicContact CB-CE2 4.22Å; Q275-F279 WeakPolarHBondContact O-CD2 3.46Å; Q275-F279 PolarHBondContact O-N 3.1Å
276	K	88.1	Confident	88.5	Confident	118 Å²	118	68.2 Å²	68.2	51%	0.513	33%	0.331	S	S	.	.	H	α-helix	trans	-58.6	-38.9	178.7	-172.8	175.6	-179.3	178.2	0	112	I272 L273 N280	I272-K276 PolarHBondContact O-N 3.21Å; L273-K276 WeakPolarHBondContact O-CB 3.45Å; L273-K276 PolarHBondContact O-N 3.32Å; K276-N280 WeakPolarHBondContact O-CB 3.31Å; K276-N280 PolarHBondContact O-N 3.48Å
277	V	88.2	Confident	88.5	Confident	2 Å²	2	70 Å²	70	1%	0.012	34%	0.342	C	S	.	.	H	α-helix	trans	-59	-47.7	173.4	164	0	0	0	0	111.2	L273 R274 Q275 N281 Y282 Y289 S290 I293	L273-V277 VanDerWaalsContact O-CG2 3.29Å; L273-V277 WeakPolarHBondContact O-CG2 3.36Å; L273-V277 PolarHBondContact O-N 3.38Å; R274-V277 WeakPolarHBondContact O-CB 3.05Å; R274-V277 PolarHBondContact O-N 3.12Å; Q275-V277 PolarHBondContact O-N 3.06Å; V277-N281 PolarHBondContact O-N 3.35Å; V277-Y282 HydrophobicContact CG2-CD2 4.13Å; V277-Y282 PolarHBondContact O-N 3.41Å; V277-Y289 HydrophobicContact CG2-CD1 4.06Å; V277-Y289 HydrophobicContact CG2-CE1 3.59Å; V277-S290 WeakPolarHBondContact CG1-OG 3.37Å; V277-I293 HydrophobicContact CG2-CB 4.34Å; V277-I293 HydrophobicContact CG2-CG1 4.23Å; V277-I293 HydrophobicContact CG2-CG2 4.28Å
278	H	83.1	Confident	88.6	Confident	66 Å²	66	76 Å²	76	31%	0.306	37%	0.373	S	S	.	.	H	α-helix	trans	-67.2	-45	177.8	-70.6	-63.2	0	0	0	112.3	R274 Q275 N280 N281 E283	R274-H278 PolarHBondContact O-CD2 3.46Å; R274-H278 PolarHBondContact O-N 3.1Å; R274-H278 VanDerWaalsContact O-N 3.1Å; Q275-H278 PolarHBondContact O-N 3.09Å; Q275-H278 VanDerWaalsContact O-N 3.07Å; H278-N280 VanDerWaalsContact C-N 3.34Å; H278-N280 PolarHBondContact O-N 3.33Å; H278-N281 PolarHBondContact O-N 3.01Å; H278-E283 IonicContact CE1-OE1 3.12Å; H278-E283 PolarHBondContact CE1-OE1 3.05Å; H278-E283 IonicContact CG-OE1 2.72Å; H278-E283 IonicContact ND1-OE1 3.97Å; H278-E283 PolarHBondContact ND1-OE1 2.83Å
279	F	84.7	Confident	88.8	Confident	108 Å²	108	80 Å²	80	47%	0.474	39%	0.387	S	S	.	.	H	α-helix	trans	-63	-37.9	-179.2	-83.4	-66.4	0	0	0	113.2	Y201 Q275 N281	Y201-F279 AromaticContact CZ-CZ 3.9Å; Y201-F279 WeakPolarHBondContact OH-CZ 3.42Å; Q275-F279 HydrophobicContact CB-CD2 4.2Å; Q275-F279 HydrophobicContact CB-CE2 4.22Å; Q275-F279 WeakPolarHBondContact O-CD2 3.46Å; Q275-F279 PolarHBondContact O-N 3.1Å; F279-N281 VanDerWaalsContact C-N 3.28Å; F279-N281 PolarHBondContact O-N 3.34Å
280	N	88.8	Confident	88.8	Confident	69 Å²	69	76.8 Å²	76.8	37%	0.369	37%	0.368	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.4	9.8	-178.6	-66.7	-11.6	0	0	0	113.2	K276 H278 Y282	K276-N280 WeakPolarHBondContact O-CB 3.31Å; K276-N280 PolarHBondContact O-N 3.48Å; H278-N280 VanDerWaalsContact C-N 3.34Å; H278-N280 PolarHBondContact O-N 3.33Å; N280-Y282 HydrophobicContact CB-CD1 3.66Å; N280-Y282 HydrophobicContact CB-CE1 3.49Å; N280-Y282 VanDerWaalsContact CB-CE1 3.49Å; N280-Y282 HydrophobicContact CB-CE2 4.48Å; N280-Y282 HydrophobicContact CB-CG 4.25Å; N280-Y282 WeakPolarHBondContact O-CD1 3.43Å; N280-Y282 PolarHBondContact O-N 2.86Å
281	N	86.7	Confident	88.8	Confident	101 Å²	101	79.6 Å²	79.6	54%	0.54	38%	0.378	S	S	.	.	T	Hydrogen-bonded Turn	trans	51.4	37.1	-176.7	-61.3	-43.2	0	0	0	113.3	V277 H278 F279 E283 L284 L285	V277-N281 PolarHBondContact O-N 3.35Å; H278-N281 PolarHBondContact O-N 3.01Å; F279-N281 VanDerWaalsContact C-N 3.28Å; F279-N281 PolarHBondContact O-N 3.34Å; N281-E283 PolarHBondContact O-N 3.07Å; N281-E283 VanDerWaalsContact O-N 3.13Å; N281-L284 PolarHBondContact O-N 3.47Å; N281-L285 PolarHBondContact O-N 2.92Å
282	Y	89.3	Confident	89.1	Confident	65 Å²	65	82.7 Å²	82.7	26%	0.255	39%	0.391	S	S	.	.	H	α-helix	trans	-66.7	-11.9	177.8	-74.9	-1.7	0	0	0	112.9	V277 N280 L284 L285 Y286 Y289	V277-Y282 HydrophobicContact CG2-CD2 4.13Å; V277-Y282 PolarHBondContact O-N 3.41Å; N280-Y282 HydrophobicContact CB-CD1 3.66Å; N280-Y282 HydrophobicContact CB-CE1 3.49Å; N280-Y282 VanDerWaalsContact CB-CE1 3.49Å; N280-Y282 HydrophobicContact CB-CE2 4.48Å; N280-Y282 HydrophobicContact CB-CG 4.25Å; N280-Y282 WeakPolarHBondContact O-CD1 3.43Å; N280-Y282 PolarHBondContact O-N 2.86Å; Y282-L284 PolarHBondContact O-N 3.29Å; Y282-L285 HydrophobicContact CD1-CD1 4.16Å; Y282-L285 HydrophobicContact CE1-CD1 4.42Å; Y282-Y286 HydrophobicContact CD1-CD2 4.17Å; Y282-Y286 HydrophobicContact CE1-CD2 4.44Å; Y282-Y286 HydrophobicContact CG-CD2 4.38Å; Y282-Y286 CarbonylContact O-C 3.45Å; Y282-Y286 WeakPolarHBondContact O-CA 3.38Å; Y282-Y286 PolarHBondContact O-N 3.31Å; Y282-Y286 VanDerWaalsContact O-O 3.11Å; Y282-Y289 HydrophobicContact CD2-CD1 4.09Å; Y282-Y289 HydrophobicContact CD2-CE1 4.02Å; Y282-Y289 HydrophobicContact CE2-CE1 4.43Å
283	E	86	Confident	89.4	Confident	97 Å²	97	79.6 Å²	79.6	45%	0.453	37%	0.374	S	S	.	.	H	α-helix	trans	-58.8	-36.7	166.6	-67.3	178.2	-170	0	0	112.5	H278 N281 S290	H278-E283 IonicContact CE1-OE1 3.12Å; H278-E283 PolarHBondContact CE1-OE1 3.05Å; H278-E283 IonicContact CG-OE1 2.72Å; H278-E283 IonicContact ND1-OE1 3.97Å; H278-E283 PolarHBondContact ND1-OE1 2.83Å; N281-E283 PolarHBondContact O-N 3.07Å; N281-E283 VanDerWaalsContact O-N 3.13Å; E283-S290 WeakPolarHBondContact CG-OG 3.47Å
284	L	89.2	Confident	89.4	Confident	150 Å²	150	78.4 Å²	78.4	79%	0.785	37%	0.368	S	S	*	.	H	α-helix	trans	-86.3	-42	178.2	-62.4	175	0	0	0	111.6	N281 Y282	N281-L284 PolarHBondContact O-N 3.47Å; Y282-L284 PolarHBondContact O-N 3.29Å
285	L	92.1	Very high	89.6	Confident	112 Å²	112	75.1 Å²	75.1	59%	0.586	36%	0.356	S	S	*	.	H	α-helix	trans	-79.9	-39.1	-174	-63.2	170.5	0	0	0	113.2	N281 Y282	N281-L285 PolarHBondContact O-N 2.92Å; Y282-L285 HydrophobicContact CD1-CD1 4.16Å; Y282-L285 HydrophobicContact CE1-CD1 4.42Å
286	Y	92	Very high	90	Very high	145 Å²	145	76.4 Å²	76.4	57%	0.569	36%	0.363	S	S	*	.			trans	-142.7	66.2	-173.2	-60.4	-74.2	0	0	0	111.3	Y282 I288 Y289 S290	Y282-Y286 HydrophobicContact CD1-CD2 4.17Å; Y282-Y286 HydrophobicContact CE1-CD2 4.44Å; Y282-Y286 HydrophobicContact CG-CD2 4.38Å; Y282-Y286 CarbonylContact O-C 3.45Å; Y282-Y286 WeakPolarHBondContact O-CA 3.38Å; Y282-Y286 PolarHBondContact O-N 3.31Å; Y282-Y286 VanDerWaalsContact O-O 3.11Å; Y286-I288 VanDerWaalsContact C-N 3.29Å; Y286-I288 PolarHBondContact O-N 2.82Å; Y286-Y289 PolarHBondContact O-N 3.49Å; Y286-S290 PolarHBondContact O-N 3.37Å
287	P	91.5	Very high	90.3	Very high	79 Å²	79	70.8 Å²	70.8	51%	0.513	34%	0.339	S	S	.	.	H	α-helix	trans	-57.8	-38.5	-171.6	20.9	-33.3	0	0	0	113.1	Y289 S290 Y291	P287-Y289 PolarHBondContact O-N 3.29Å; P287-S290 PolarHBondContact O-N 2.98Å; P287-Y291 VanDerWaalsContact O-CB 3.29Å; P287-Y291 WeakPolarHBondContact O-CB 3.49Å; P287-Y291 PolarHBondContact O-N 3.37Å
288	I	91.4	Very high	90.5	Very high	129 Å²	129	74 Å²	74	66%	0.662	35%	0.353	S	S	*	.	H	α-helix	trans	-62.8	-44	178.5	-60.1	170.6	0	0	0	111	Y286 Y291 K292	Y286-I288 VanDerWaalsContact C-N 3.29Å; Y286-I288 PolarHBondContact O-N 2.82Å; I288-Y291 PolarHBondContact O-N 3.47Å; I288-K292 HydrophobicContact CG2-CD 4.4Å; I288-K292 VanDerWaalsContact O-CG 3.3Å; I288-K292 WeakPolarHBondContact O-CG 3.43Å; I288-K292 PolarHBondContact O-N 3.39Å; I288-K292 VanDerWaalsContact O-N 3.07Å
289	Y	92	Very high	91.1	Very high	100 Å²	100	71 Å²	71	39%	0.392	34%	0.339	S	S	.	.	H	α-helix	trans	-66.5	-45.8	178.2	175.9	-102.9	0	0	0	111.1	V277 Y282 Y286 P287 Y291 K292 I293	V277-Y289 HydrophobicContact CG2-CD1 4.06Å; V277-Y289 HydrophobicContact CG2-CE1 3.59Å; Y282-Y289 HydrophobicContact CD2-CD1 4.09Å; Y282-Y289 HydrophobicContact CD2-CE1 4.02Å; Y282-Y289 HydrophobicContact CE2-CE1 4.43Å; Y286-Y289 PolarHBondContact O-N 3.49Å; P287-Y289 PolarHBondContact O-N 3.29Å; Y289-Y291 VanDerWaalsContact C-N 3.31Å; Y289-Y291 PolarHBondContact O-N 2.94Å; Y289-K292 PolarHBondContact O-N 3.48Å; Y289-I293 HydrophobicContact CD1-CG1 4.43Å; Y289-I293 HydrophobicContact CD2-CG1 4.46Å; Y289-I293 HydrophobicContact CE1-CG1 4Å; Y289-I293 HydrophobicContact CE2-CD1 4.12Å; Y289-I293 HydrophobicContact CE2-CG1 4.02Å; Y289-I293 WeakPolarHBondContact O-CG1 3.11Å; Y289-I293 PolarHBondContact O-N 2.97Å; Y289-I293 VanDerWaalsContact O-N 3.07Å
290	S	91.3	Very high	91.6	Very high	4 Å²	4	68.4 Å²	68.4	3%	0.028	33%	0.328	C	S	.	.	H	α-helix	trans	-55.7	-48.1	175.9	-179.2	0	0	0	0	111.5	V277 E283 Y286 P287 K292 I293 I294	V277-S290 WeakPolarHBondContact CG1-OG 3.37Å; E283-S290 WeakPolarHBondContact CG-OG 3.47Å; Y286-S290 PolarHBondContact O-N 3.37Å; P287-S290 PolarHBondContact O-N 2.98Å; S290-K292 PolarHBondContact O-N 3.4Å; S290-I293 PolarHBondContact O-N 3.03Å; S290-I294 WeakPolarHBondContact O-CG1 3.41Å; S290-I294 PolarHBondContact O-N 3.39Å
291	Y	91.1	Very high	91.7	Very high	81 Å²	81	66.6 Å²	66.6	32%	0.318	32%	0.321	S	S	.	.	H	α-helix	trans	-58.5	-47.3	178.7	-168.2	-103.4	0	0	0	112.6	T16 E19 P287 I288 Y289 I293 I294 Q295	T16-Y291 HydrophobicContact CG2-CD1 3.83Å; T16-Y291 HydrophobicContact CG2-CE1 3.57Å; T16-Y291 WeakPolarHBondContact OG1-CE1 3.47Å; E19-Y291 PolarHBondContact OE1-OH 3.29Å; E19-Y291 PolarHBondContact OE2-OH 3.27Å; P287-Y291 VanDerWaalsContact O-CB 3.29Å; P287-Y291 WeakPolarHBondContact O-CB 3.49Å; P287-Y291 PolarHBondContact O-N 3.37Å; I288-Y291 PolarHBondContact O-N 3.47Å; Y289-Y291 VanDerWaalsContact C-N 3.31Å; Y289-Y291 PolarHBondContact O-N 2.94Å; Y291-I293 PolarHBondContact O-N 3.2Å; Y291-I294 PolarHBondContact O-N 2.78Å; Y291-Q295 HydrophobicContact CD1-CG 4.12Å; Y291-Q295 HydrophobicContact CE1-CG 3.78Å; Y291-Q295 VanDerWaalsContact CZ-NE2 3.28Å; Y291-Q295 WeakPolarHBondContact O-CG 3.44Å; Y291-Q295 PolarHBondContact O-N 3.5Å; Y291-Q295 PolarHBondContact OH-NE2 3Å
292	K	93.5	Very high	92.2	Very high	80 Å²	80	61.8 Å²	61.8	35%	0.348	30%	0.295	S	S	.	.	H	α-helix	trans	-58.2	-46.6	177.2	-73.3	176.6	179.1	-110.8	0	112	E18 I288 Y289 S290 I294 Q295 L296	E18-K292 HydrophobicContact CG-CG 4.23Å; E18-K292 WeakPolarHBondContact OE1-CD 3.29Å; E18-K292 WeakPolarHBondContact OE1-CE 3.34Å; E18-K292 WeakPolarHBondContact OE1-CG 3.39Å; E18-K292 IonicContact OE1-NZ 3.1Å; E18-K292 PolarHBondContact OE1-NZ 2.93Å; I288-K292 HydrophobicContact CG2-CD 4.4Å; I288-K292 VanDerWaalsContact O-CG 3.3Å; I288-K292 WeakPolarHBondContact O-CG 3.43Å; I288-K292 PolarHBondContact O-N 3.39Å; I288-K292 VanDerWaalsContact O-N 3.07Å; Y289-K292 PolarHBondContact O-N 3.48Å; S290-K292 PolarHBondContact O-N 3.4Å; K292-I294 VanDerWaalsContact C-N 3.33Å; K292-I294 PolarHBondContact O-N 3.3Å; K292-Q295 PolarHBondContact O-N 2.97Å; K292-L296 WeakPolarHBondContact O-CB 3.29Å; K292-L296 WeakPolarHBondContact O-CG 3.37Å; K292-L296 PolarHBondContact O-N 3.33Å
293	I	93.3	Very high	92.5	Very high	11 Å²	11	60.3 Å²	60.3	6%	0.056	29%	0.291	C	S	.	.	H	α-helix	trans	-63.2	-41.1	178.9	-65.4	-63.2	0	0	0	111	L273 R274 V277 Y289 S290 Y291 L296 S297	L273-I293 HydrophobicContact CB-CG2 4.33Å; R274-I293 HydrophobicContact CB-CG2 3.83Å; V277-I293 HydrophobicContact CG2-CB 4.34Å; V277-I293 HydrophobicContact CG2-CG1 4.23Å; V277-I293 HydrophobicContact CG2-CG2 4.28Å; Y289-I293 HydrophobicContact CD1-CG1 4.43Å; Y289-I293 HydrophobicContact CD2-CG1 4.46Å; Y289-I293 HydrophobicContact CE1-CG1 4Å; Y289-I293 HydrophobicContact CE2-CD1 4.12Å; Y289-I293 HydrophobicContact CE2-CG1 4.02Å; Y289-I293 WeakPolarHBondContact O-CG1 3.11Å; Y289-I293 PolarHBondContact O-N 2.97Å; Y289-I293 VanDerWaalsContact O-N 3.07Å; S290-I293 PolarHBondContact O-N 3.03Å; Y291-I293 PolarHBondContact O-N 3.2Å; I293-L296 PolarHBondContact O-N 2.88Å; I293-S297 VanDerWaalsContact O-CB 3.29Å; I293-S297 WeakPolarHBondContact O-CB 3.36Å; I293-S297 PolarHBondContact O-N 3.03Å
294	I	91.3	Very high	92.9	Very high	32 Å²	32	56.6 Å²	56.6	16%	0.164	27%	0.274	C	S	.	.	H	α-helix	trans	-61.6	-45.9	176.1	-68.4	165.4	0	0	0	110.9	S290 Y291 K292 S297 K298	S290-I294 WeakPolarHBondContact O-CG1 3.41Å; S290-I294 PolarHBondContact O-N 3.39Å; Y291-I294 PolarHBondContact O-N 2.78Å; K292-I294 VanDerWaalsContact C-N 3.33Å; K292-I294 PolarHBondContact O-N 3.3Å; I294-S297 WeakPolarHBondContact O-CB 3.29Å; I294-S297 PolarHBondContact O-N 3.02Å; I294-S297 PolarHBondContact O-OG 2.97Å; I294-K298 WeakPolarHBondContact O-CG 3.46Å; I294-K298 PolarHBondContact O-N 3.42Å; I294-K298 VanDerWaalsContact O-N 3.15Å
295	Q	93.2	Very high	93.2	Very high	5 Å²	5	49.5 Å²	49.5	2%	0.023	24%	0.237	C	C	.	.	H	α-helix	trans	-67.3	-42.8	179.6	-64.4	-62	-6.1	0	0	112.2	E18 E19 V22 Y291 K292 S297 K298 L299	E18-Q295 HydrophobicContact CB-CB 3.93Å; E19-Q295 HydrophobicContact CB-CG 4.22Å; V22-Q295 HydrophobicContact CG2-CB 4.38Å; V22-Q295 VanDerWaalsContact CG2-O 3.25Å; V22-Q295 WeakPolarHBondContact CG2-O 3.49Å; Y291-Q295 HydrophobicContact CD1-CG 4.12Å; Y291-Q295 HydrophobicContact CE1-CG 3.78Å; Y291-Q295 VanDerWaalsContact CZ-NE2 3.28Å; Y291-Q295 WeakPolarHBondContact O-CG 3.44Å; Y291-Q295 PolarHBondContact O-N 3.5Å; Y291-Q295 PolarHBondContact OH-NE2 3Å; K292-Q295 PolarHBondContact O-N 2.97Å; Q295-S297 VanDerWaalsContact C-N 3.26Å; Q295-S297 PolarHBondContact O-N 3.1Å; Q295-K298 WeakPolarHBondContact O-CB 3.23Å; Q295-K298 PolarHBondContact O-N 3.38Å; Q295-K298 VanDerWaalsContact O-N 3.14Å; Q295-L299 PolarHBondContact O-N 3.27Å
296	L	94	Very high	93.4	Very high	50 Å²	50	46.6 Å²	46.6	26%	0.262	22%	0.22	S	C	.	.	H	α-helix	trans	-58.6	-39.5	172.2	-74.4	170.1	0	0	0	111.7	I270 K292 I293 K298 L299 F300	I270-L296 HydrophobicContact CD1-CB 4.48Å; I270-L296 HydrophobicContact CG2-CB 4.32Å; K292-L296 WeakPolarHBondContact O-CB 3.29Å; K292-L296 WeakPolarHBondContact O-CG 3.37Å; K292-L296 PolarHBondContact O-N 3.33Å; I293-L296 PolarHBondContact O-N 2.88Å; L296-K298 VanDerWaalsContact C-N 3.3Å; L296-K298 PolarHBondContact O-N 3.16Å; L296-L299 HydrophobicContact CD2-CD2 4.4Å; L296-L299 WeakPolarHBondContact O-CB 3.28Å; L296-L299 PolarHBondContact O-N 3.43Å; L296-F300 WeakPolarHBondContact O-CD2 3.27Å; L296-F300 PolarHBondContact O-N 2.91Å
297	S	92.8	Very high	93.6	Very high	1 Å²	1	40 Å²	40	1%	0.007	19%	0.194	C	C	.	.	H	α-helix	trans	-61.9	-38.1	177.8	87.9	0	0	0	0	112.2	I270 M271 R274 I293 I294 Q295 S301	I270-S297 VanDerWaalsContact CG2-CA 3.44Å; M271-S297 VanDerWaalsContact CE-CB 3.46Å; R274-S297 WeakPolarHBondContact CD-OG 3.48Å; R274-S297 PolarHBondContact NH1-OG 3.02Å; I293-S297 VanDerWaalsContact O-CB 3.29Å; I293-S297 WeakPolarHBondContact O-CB 3.36Å; I293-S297 PolarHBondContact O-N 3.03Å; I294-S297 WeakPolarHBondContact O-CB 3.29Å; I294-S297 PolarHBondContact O-N 3.02Å; I294-S297 PolarHBondContact O-OG 2.97Å; Q295-S297 VanDerWaalsContact C-N 3.26Å; Q295-S297 PolarHBondContact O-N 3.1Å; S297-S301 WeakPolarHBondContact O-CB 3.32Å; S297-S301 PolarHBondContact O-N 2.84Å; S297-S301 VanDerWaalsContact O-N 3.1Å
298	K	93.1	Very high	93.7	Very high	68 Å²	68	36.7 Å²	36.7	30%	0.296	17%	0.172	S	C	.	.	H	α-helix	trans	-69.7	-40.9	174.8	-66.5	171.5	-176.8	173.3	0	111.5	V22 I294 Q295 L296 S301 S302	V22-K298 HydrophobicContact CG1-CB 4.3Å; V22-K298 HydrophobicContact CG2-CB 4.39Å; I294-K298 WeakPolarHBondContact O-CG 3.46Å; I294-K298 PolarHBondContact O-N 3.42Å; I294-K298 VanDerWaalsContact O-N 3.15Å; Q295-K298 WeakPolarHBondContact O-CB 3.23Å; Q295-K298 PolarHBondContact O-N 3.38Å; Q295-K298 VanDerWaalsContact O-N 3.14Å; L296-K298 VanDerWaalsContact C-N 3.3Å; L296-K298 PolarHBondContact O-N 3.16Å; K298-S301 PolarHBondContact O-N 3.34Å; K298-S302 PolarHBondContact O-N 3.39Å; K298-S302 PolarHBondContact O-OG 3.04Å
299	L	95.3	Very high	94	Very high	5 Å²	5	30.6 Å²	30.6	3%	0.026	14%	0.141	C	C	.	.	H	α-helix	trans	-61	-52.2	177.1	179.8	68.3	0	0	0	111.3	M21 V22 F25 Q295 L296 S301 S302 I303	M21-L299 HydrophobicContact CE-CD1 4.34Å; M21-L299 HydrophobicContact CE-CD2 3.55Å; M21-L299 HydrophobicContact CG-CD1 4.08Å; M21-L299 HydrophobicContact CG-CD2 4.01Å; M21-L299 HydrophobicContact SD-CD2 3.44Å; M21-L299 WeakPolarHBondContact SD-CD2 3.35Å; V22-L299 HydrophobicContact CG2-CB 3.81Å; F25-L299 HydrophobicContact CB-CD1 4Å; F25-L299 HydrophobicContact CD2-CD1 4.37Å; F25-L299 HydrophobicContact CG-CD1 4.21Å; Q295-L299 PolarHBondContact O-N 3.27Å; L296-L299 HydrophobicContact CD2-CD2 4.4Å; L296-L299 WeakPolarHBondContact O-CB 3.28Å; L296-L299 PolarHBondContact O-N 3.43Å; L299-S301 VanDerWaalsContact C-N 3.28Å; L299-S301 PolarHBondContact O-N 2.85Å; L299-S302 WeakPolarHBondContact O-CA 3.43Å; L299-S302 WeakPolarHBondContact O-CB 3.33Å; L299-S302 PolarHBondContact O-N 3.14Å; L299-I303 HydrophobicContact CD1-CD1 4.39Å; L299-I303 HydrophobicContact CD2-CD1 4.48Å; L299-I303 HydrophobicContact CG-CD1 3.95Å; L299-I303 WeakPolarHBondContact O-CG1 3.34Å; L299-I303 PolarHBondContact O-N 3Å
300	F	94.6	Very high	94.2	Very high	52 Å²	52	29.8 Å²	29.8	23%	0.228	14%	0.14	C	C	.	.	H	α-helix	trans	-64.6	-33.1	179.4	-83.2	-77.2	0	0	0	112.4	P266 L267 I270 L296 S302 I303 D304	P266-F300 HydrophobicContact CB-CD1 3.69Å; P266-F300 HydrophobicContact CB-CE1 3.38Å; P266-F300 HydrophobicContact CB-CZ 4.06Å; P266-F300 HydrophobicContact CG-CE1 4.3Å; L267-F300 HydrophobicContact CB-CB 4.31Å; L267-F300 HydrophobicContact CD1-CB 3.86Å; I270-F300 HydrophobicContact CG1-CD2 3.91Å; I270-F300 HydrophobicContact CG1-CE2 4.11Å; L296-F300 WeakPolarHBondContact O-CD2 3.27Å; L296-F300 PolarHBondContact O-N 2.91Å; F300-S302 VanDerWaalsContact C-N 3.32Å; F300-I303 HydrophobicContact CD1-CD1 4.29Å; F300-I303 PolarHBondContact O-N 3.12Å; F300-D304 PolarHBondContact O-N 2.72Å
301	S	92.8	Very high	94.4	Very high	32 Å²	32	29.8 Å²	29.8	22%	0.224	14%	0.139	C	C	.	.	H	α-helix	trans	-62.3	-40.5	170.7	-172.7	0	0	0	0	111.7	S297 K298 L299 D304	S297-S301 WeakPolarHBondContact O-CB 3.32Å; S297-S301 PolarHBondContact O-N 2.84Å; S297-S301 VanDerWaalsContact O-N 3.1Å; K298-S301 PolarHBondContact O-N 3.34Å; L299-S301 VanDerWaalsContact C-N 3.28Å; L299-S301 PolarHBondContact O-N 2.85Å; S301-D304 WeakPolarHBondContact O-CB 3.39Å; S301-D304 PolarHBondContact O-N 2.75Å
302	S	95.4	Very high	94.7	Very high	0 Å²	0	27.3 Å²	27.3	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-67.3	-39.6	175.8	-48.3	0	0	0	0	111.4	R26 K298 L299 F300 D304 S305	R26-S302 PolarHBondContact NE-OG 3.39Å; K298-S302 PolarHBondContact O-N 3.39Å; K298-S302 PolarHBondContact O-OG 3.04Å; L299-S302 WeakPolarHBondContact O-CA 3.43Å; L299-S302 WeakPolarHBondContact O-CB 3.33Å; L299-S302 PolarHBondContact O-N 3.14Å; F300-S302 VanDerWaalsContact C-N 3.32Å; S302-D304 VanDerWaalsContact C-N 3.27Å; S302-D304 PolarHBondContact O-N 3.15Å; S302-S305 WeakPolarHBondContact O-CB 3.46Å; S302-S305 PolarHBondContact O-N 2.97Å; S302-S305 VanDerWaalsContact O-N 3.16Å; S302-S305 PolarHBondContact O-OG 2.88Å
303	I	96	Very high	94.9	Very high	33 Å²	33	27.6 Å²	27.6	17%	0.169	13%	0.131	C	C	.	.	H	α-helix	trans	-62.8	-31.9	176.1	-70	169.4	0	0	0	111.6	F25 L263 L299 F300 S305 F306	F25-I303 HydrophobicContact CD2-CG1 4.39Å; F25-I303 HydrophobicContact CE2-CG1 3.78Å; F25-I303 HydrophobicContact CZ-CG1 3.94Å; L263-I303 HydrophobicContact CD2-CG2 4.01Å; L299-I303 HydrophobicContact CD1-CD1 4.39Å; L299-I303 HydrophobicContact CD2-CD1 4.48Å; L299-I303 HydrophobicContact CG-CD1 3.95Å; L299-I303 WeakPolarHBondContact O-CG1 3.34Å; L299-I303 PolarHBondContact O-N 3Å; F300-I303 HydrophobicContact CD1-CD1 4.29Å; F300-I303 PolarHBondContact O-N 3.12Å; I303-S305 PolarHBondContact O-N 2.91Å; I303-F306 HydrophobicContact CG2-CD2 4.14Å; I303-F306 WeakPolarHBondContact O-CB 3.41Å; I303-F306 VanDerWaalsContact O-CD2 3.23Å; I303-F306 WeakPolarHBondContact O-CD2 3.36Å; I303-F306 PolarHBondContact O-N 3.21Å
304	D	94.1	Very high	95	Very high	19 Å²	19	28.4 Å²	28.4	10%	0.102	14%	0.136	C	C	.	.	H	α-helix	trans	-59.3	-22.1	176.7	-162.5	49.1	0	0	0	112.5	L267 F300 S301 S302 F306 N307 H308	L267-D304 HydrophobicContact CD2-CB 4.2Å; F300-D304 PolarHBondContact O-N 2.72Å; S301-D304 WeakPolarHBondContact O-CB 3.39Å; S301-D304 PolarHBondContact O-N 2.75Å; S302-D304 VanDerWaalsContact C-N 3.27Å; S302-D304 PolarHBondContact O-N 3.15Å; D304-F306 PolarHBondContact O-N 2.96Å; D304-N307 VanDerWaalsContact O-CB 3.3Å; D304-N307 WeakPolarHBondContact O-CB 3.37Å; D304-N307 PolarHBondContact O-N 2.94Å; D304-N307 PolarHBondContact OD1-ND2 2.65Å; D304-H308 IonicContact OD2-NE2 3.62Å
305	S	95.9	Very high	95.3	Very high	1 Å²	1	26.9 Å²	26.9	1%	0.007	13%	0.128	C	C	.	.	H	α-helix	trans	-56.4	-21.6	172.3	-55.6	0	0	0	0	114.2	T78 S302 I303 N307 H308 T309	T78-S305 WeakPolarHBondContact OG1-CB 3.44Å; T78-S305 PolarHBondContact OG1-OG 3.36Å; S302-S305 WeakPolarHBondContact O-CB 3.46Å; S302-S305 PolarHBondContact O-N 2.97Å; S302-S305 VanDerWaalsContact O-N 3.16Å; S302-S305 PolarHBondContact O-OG 2.88Å; I303-S305 PolarHBondContact O-N 2.91Å; S305-N307 VanDerWaalsContact C-N 3.3Å; S305-N307 PolarHBondContact O-N 2.97Å; S305-H308 PolarHBondContact O-N 2.89Å; S305-T309 PolarHBondContact O-N 2.69Å; S305-T309 PolarHBondContact O-OG1 3.4Å
306	F	97.2	Very high	95.5	Very high	52 Å²	52	31.9 Å²	31.9	23%	0.228	15%	0.147	C	C	.	.	H	α-helix	trans	-62.7	-36.2	171.8	-80	-71	0	0	0	112.2	F25 I29 L33 L263 I303 D304 H308 T309 F310	F25-F306 AromaticContact CE2-CE2 3.93Å; F25-F306 HydrophobicContact CE2-CE2 3.93Å; F25-F306 HydrophobicContact CZ-CD2 4.4Å; F25-F306 AromaticContact CZ-CE2 3.79Å; F25-F306 HydrophobicContact CZ-CE2 3.79Å; I29-F306 HydrophobicContact CG2-CE2 4.43Å; I29-F306 HydrophobicContact CG2-CZ 4.03Å; L33-F306 HydrophobicContact CD1-CD1 4.2Å; L33-F306 HydrophobicContact CD1-CD2 4.27Å; L33-F306 HydrophobicContact CD1-CE1 4.26Å; L33-F306 HydrophobicContact CD1-CE2 4.25Å; L33-F306 HydrophobicContact CD1-CG 4.26Å; L33-F306 HydrophobicContact CD1-CZ 4.27Å; L33-F306 HydrophobicContact CD2-CD1 3.53Å; L33-F306 HydrophobicContact CD2-CE1 3.53Å; L33-F306 HydrophobicContact CD2-CG 4.34Å; L33-F306 HydrophobicContact CD2-CZ 4.25Å; L33-F306 HydrophobicContact CG-CE1 4.41Å; L263-F306 HydrophobicContact CD1-CB 3.73Å; I303-F306 HydrophobicContact CG2-CD2 4.14Å; I303-F306 WeakPolarHBondContact O-CB 3.41Å; I303-F306 VanDerWaalsContact O-CD2 3.23Å; I303-F306 WeakPolarHBondContact O-CD2 3.36Å; I303-F306 PolarHBondContact O-N 3.21Å; D304-F306 PolarHBondContact O-N 2.96Å; F306-H308 VanDerWaalsContact C-N 3.33Å; F306-H308 PolarHBondContact O-N 3.33Å; F306-T309 PolarHBondContact O-N 3.08Å; F306-F310 HydrophobicContact CB-CD2 4.04Å; F306-F310 HydrophobicContact CB-CE2 4.11Å; F306-F310 AromaticContact CD1-CD2 3.89Å; F306-F310 HydrophobicContact CD1-CD2 3.89Å; F306-F310 AromaticContact CD1-CE2 3.17Å; F306-F310 HydrophobicContact CD1-CE2 3.17Å; F306-F310 AromaticContact CD1-CZ 3.79Å; F306-F310 HydrophobicContact CD1-CZ 3.79Å; F306-F310 AromaticContact CE1-CE2 3.84Å; F306-F310 HydrophobicContact CE1-CE2 3.84Å; F306-F310 HydrophobicContact CE1-CZ 4.07Å; F306-F310 HydrophobicContact CG-CD2 4.44Å; F306-F310 HydrophobicContact CG-CE2 4.03Å; F306-F310 WeakPolarHBondContact O-CB 3.35Å; F306-F310 WeakPolarHBondContact O-CD2 3.25Å; F306-F310 PolarHBondContact O-N 3.1Å
307	N	95.1	Very high	95.6	Very high	5 Å²	5	31.5 Å²	31.5	3%	0.027	15%	0.151	C	C	.	.	H	α-helix	trans	-58.3	-46.9	176.6	-82.4	-39.3	0	0	0	111	M259 F260 L263 D304 S305 T309	M259-N307 HydrophobicContact CE-CB 4.41Å; M259-N307 WeakPolarHBondContact CE-O 3.33Å; M259-N307 PolarHBondContact O-OD1 3.26Å; F260-N307 WeakPolarHBondContact CA-OD1 3.38Å; F260-N307 PolarHBondContact N-OD1 2.95Å; L263-N307 WeakPolarHBondContact CB-ND2 3.42Å; L263-N307 WeakPolarHBondContact CD1-OD1 3.43Å; D304-N307 VanDerWaalsContact O-CB 3.3Å; D304-N307 WeakPolarHBondContact O-CB 3.37Å; D304-N307 PolarHBondContact O-N 2.94Å; D304-N307 PolarHBondContact OD1-ND2 2.65Å; S305-N307 VanDerWaalsContact C-N 3.3Å; S305-N307 PolarHBondContact O-N 2.97Å; N307-T309 VanDerWaalsContact C-N 3.3Å; N307-T309 PolarHBondContact O-N 3.25Å
308	H	95.2	Very high	95.7	Very high	11 Å²	11	34.5 Å²	34.5	5%	0.051	16%	0.164	C	C	.	.	H	α-helix	trans	-72	-25.2	-178.1	-48.4	-43.7	0	0	0	113	N41 H70 Q73 L74 D304 S305 F306	N41-H308 PolarHBondContact ND2-O 3.49Å; H70-H308 HydrophobicContact CB-CB 3.96Å; H70-H308 AromaticContact CD2-CE1 3.84Å; H70-H308 AromaticContact CD2-CG 3.88Å; H70-H308 AromaticContact CD2-ND1 3.02Å; H70-H308 PolarHBondContact CD2-ND1 2.81Å; H70-H308 AromaticContact CE1-ND1 3.81Å; H70-H308 AromaticContact CG-ND1 3.6Å; H70-H308 AromaticContact NE2-CE1 3.88Å; H70-H308 AromaticContact NE2-ND1 3.17Å; H70-H308 PolarHBondContact NE2-ND1 3.14Å; H70-H308 VanDerWaalsContact NE2-ND1 3.17Å; Q73-H308 VanDerWaalsContact CG-CD2 3.47Å; Q73-H308 WeakPolarHBondContact CG-CD2 3.46Å; Q73-H308 WeakPolarHBondContact CG-NE2 3.44Å; L74-H308 HydrophobicContact CD1-CB 4.2Å; L74-H308 HydrophobicContact CD2-CB 4.09Å; L74-H308 HydrophobicContact CG-CB 3.89Å; D304-H308 IonicContact OD2-NE2 3.62Å; S305-H308 PolarHBondContact O-N 2.89Å; F306-H308 VanDerWaalsContact C-N 3.33Å; F306-H308 PolarHBondContact O-N 3.33Å
309	T	97.1	Very high	95.7	Very high	1 Å²	1	31.5 Å²	31.5	1%	0.006	15%	0.151	C	C	.	.	H	α-helix	trans	-83.3	-38.3	-178.7	-57.7	0	0	0	0	112.3	L33 I36 S305 F306 N307	L33-T309 HydrophobicContact CD2-CG2 4.02Å; I36-T309 HydrophobicContact CB-CG2 4.32Å; I36-T309 HydrophobicContact CG2-CG2 4.09Å; S305-T309 PolarHBondContact O-N 2.69Å; S305-T309 PolarHBondContact O-OG1 3.4Å; F306-T309 PolarHBondContact O-N 3.08Å; N307-T309 VanDerWaalsContact C-N 3.3Å; N307-T309 PolarHBondContact O-N 3.25Å
310	F	96.5	Very high	95.6	Very high	83 Å²	83	31.9 Å²	31.9	36%	0.364	15%	0.154	S	C	.	.	H	α-helix	trans	-86.1	-9.9	-167	-78.6	-49.4	0	0	0	116.1	M259 F306 F312 F313 L314	M259-F310 HydrophobicContact CE-CB 4.2Å; M259-F310 HydrophobicContact SD-CB 3.62Å; M259-F310 HydrophobicContact SD-CD2 4.34Å; M259-F310 HydrophobicContact SD-CG 4.46Å; F306-F310 HydrophobicContact CB-CD2 4.04Å; F306-F310 HydrophobicContact CB-CE2 4.11Å; F306-F310 AromaticContact CD1-CD2 3.89Å; F306-F310 HydrophobicContact CD1-CD2 3.89Å; F306-F310 AromaticContact CD1-CE2 3.17Å; F306-F310 HydrophobicContact CD1-CE2 3.17Å; F306-F310 AromaticContact CD1-CZ 3.79Å; F306-F310 HydrophobicContact CD1-CZ 3.79Å; F306-F310 AromaticContact CE1-CE2 3.84Å; F306-F310 HydrophobicContact CE1-CE2 3.84Å; F306-F310 HydrophobicContact CE1-CZ 4.07Å; F306-F310 HydrophobicContact CG-CD2 4.44Å; F306-F310 HydrophobicContact CG-CE2 4.03Å; F306-F310 WeakPolarHBondContact O-CB 3.35Å; F306-F310 WeakPolarHBondContact O-CD2 3.25Å; F306-F310 PolarHBondContact O-N 3.1Å; F310-F312 VanDerWaalsContact C-N 3.25Å; F310-F312 PolarHBondContact O-N 3.04Å; F310-F312 VanDerWaalsContact O-N 3.17Å; F310-F313 AromaticContact CD1-CD2 3.7Å; F310-F313 HydrophobicContact CD1-CD2 3.7Å; F310-F313 HydrophobicContact CD1-CE2 4.15Å; F310-F313 HydrophobicContact CD1-CG 4.44Å; F310-F313 HydrophobicContact CE1-CD2 4.41Å; F310-F313 PolarHBondContact O-N 3.06Å; F310-L314 PolarHBondContact O-N 2.66Å; F310-L314 VanDerWaalsContact O-N 3.09Å
311	D	95.2	Very high	95.5	Very high	3 Å²	3	31.5 Å²	31.5	2%	0.016	15%	0.154	C	C	.	.	H	α-helix	trans	-52.3	-41.4	179.8	-81	-8.8	0	0	0	113.5	I44 H70 F313 L314 Y315	I44-D311 HydrophobicContact CD1-CB 3.93Å; H70-D311 IonicContact CE1-OD2 3.75Å; H70-D311 PolarHBondContact CE1-OD2 3.38Å; H70-D311 IonicContact ND1-OD2 2.71Å; H70-D311 PolarHBondContact ND1-OD2 2.9Å; D311-F313 VanDerWaalsContact C-N 3.29Å; D311-F313 PolarHBondContact O-N 3.36Å; D311-L314 PolarHBondContact O-N 3.42Å; D311-L314 VanDerWaalsContact O-N 3.17Å; D311-Y315 HydrophobicContact CB-CD2 4.35Å; D311-Y315 HydrophobicContact CB-CE2 4.02Å; D311-Y315 WeakPolarHBondContact O-CD2 3.35Å; D311-Y315 PolarHBondContact O-N 3.18Å
312	F	96.8	Very high	95.6	Very high	30 Å²	30	30 Å²	30	13%	0.132	14%	0.143	C	C	.	.	H	α-helix	trans	-59.2	-43.3	178.6	173.1	-92.4	0	0	0	111.7	A40 F43 I44 F310 L314 Y315 W316 F322 L326	A40-F312 HydrophobicContact CB-CB 3.65Å; A40-F312 HydrophobicContact CB-CG 4.01Å; F43-F312 HydrophobicContact CB-CD2 4.21Å; F43-F312 HydrophobicContact CB-CE2 3.9Å; I44-F312 HydrophobicContact CD1-CB 3.87Å; I44-F312 HydrophobicContact CG1-CB 4Å; I44-F312 HydrophobicContact CG1-CD2 3.99Å; F310-F312 VanDerWaalsContact C-N 3.25Å; F310-F312 PolarHBondContact O-N 3.04Å; F310-F312 VanDerWaalsContact O-N 3.17Å; F312-L314 VanDerWaalsContact C-N 3.32Å; F312-Y315 PolarHBondContact O-N 2.98Å; F312-W316 VanDerWaalsContact O-CB 3.25Å; F312-W316 WeakPolarHBondContact O-CB 3.42Å; F312-W316 PolarHBondContact O-N 2.92Å; F312-F322 HydrophobicContact CD2-CE1 4.11Å; F312-F322 AromaticContact CD2-CZ 3.83Å; F312-F322 HydrophobicContact CD2-CZ 3.83Å; F312-F322 AromaticContact CE2-CE1 3.81Å; F312-F322 HydrophobicContact CE2-CE1 3.81Å; F312-F322 AromaticContact CE2-CZ 3.77Å; F312-F322 HydrophobicContact CE2-CZ 3.77Å; F312-F322 HydrophobicContact CZ-CE1 4.42Å; F312-L326 HydrophobicContact CE2-CD2 4.24Å; F312-L326 HydrophobicContact CZ-CD2 3.82Å
313	F	97.1	Very high	95.6	Very high	85 Å²	85	33.2 Å²	33.2	37%	0.373	16%	0.155	S	C	.	.	H	α-helix	trans	-69.1	-34.4	-179.9	-61	-82.4	0	0	0	111.1	I36 F310 D311 W316 A317	I36-F313 HydrophobicContact CG2-CE2 3.79Å; I36-F313 HydrophobicContact CG2-CZ 3.83Å; F310-F313 AromaticContact CD1-CD2 3.7Å; F310-F313 HydrophobicContact CD1-CD2 3.7Å; F310-F313 HydrophobicContact CD1-CE2 4.15Å; F310-F313 HydrophobicContact CD1-CG 4.44Å; F310-F313 HydrophobicContact CE1-CD2 4.41Å; F310-F313 PolarHBondContact O-N 3.06Å; D311-F313 VanDerWaalsContact C-N 3.29Å; D311-F313 PolarHBondContact O-N 3.36Å; F313-W316 PolarHBondContact O-N 3.44Å; F313-A317 WeakPolarHBondContact O-CB 3.39Å; F313-A317 PolarHBondContact O-N 2.74Å
314	L	97	Very high	95.6	Very high	28 Å²	28	35.6 Å²	35.6	15%	0.147	17%	0.166	C	C	.	.	H	α-helix	trans	-66.7	-46.2	173.3	-64.2	179.3	0	0	0	111.8	A255 I256 M259 F310 D311 F312 W316 A317 F318	A255-L314 HydrophobicContact CB-CD2 4.25Å; I256-L314 HydrophobicContact CB-CD1 4.27Å; I256-L314 HydrophobicContact CG1-CB 4.15Å; I256-L314 HydrophobicContact CG1-CD1 3.62Å; M259-L314 HydrophobicContact CB-CD1 4.44Å; M259-L314 HydrophobicContact CE-CD1 3.65Å; M259-L314 HydrophobicContact SD-CD1 3.82Å; F310-L314 PolarHBondContact O-N 2.66Å; F310-L314 VanDerWaalsContact O-N 3.09Å; D311-L314 PolarHBondContact O-N 3.42Å; D311-L314 VanDerWaalsContact O-N 3.17Å; F312-L314 VanDerWaalsContact C-N 3.32Å; L314-W316 VanDerWaalsContact C-N 3.34Å; L314-W316 PolarHBondContact O-N 3.5Å; L314-A317 PolarHBondContact O-N 3.05Å; L314-F318 HydrophobicContact CD2-CD2 4.31Å; L314-F318 HydrophobicContact CD2-CE2 3.9Å; L314-F318 WeakPolarHBondContact O-CD2 3.48Å; L314-F318 PolarHBondContact O-N 2.79Å
315	Y	96.7	Very high	95.6	Very high	1 Å²	1	35.4 Å²	35.4	0%	0.004	17%	0.165	C	C	.	.	H	α-helix	trans	-60.8	-44.1	173.8	-69.7	-57.1	0	0	0	111.4	I44 F48 F59 A63 T252 I256 D311 F312 L319	I44-Y315 HydrophobicContact CD1-CD2 3.86Å; I44-Y315 HydrophobicContact CD1-CE2 4.01Å; I44-Y315 HydrophobicContact CG1-CD2 4.08Å; I44-Y315 HydrophobicContact CG2-CD2 4.26Å; I44-Y315 HydrophobicContact CG2-CE2 4.09Å; F48-Y315 AromaticContact CE2-CD1 3.95Å; F48-Y315 HydrophobicContact CE2-CD1 3.95Å; F48-Y315 HydrophobicContact CE2-CD2 4Å; F48-Y315 HydrophobicContact CE2-CE1 4.07Å; F48-Y315 HydrophobicContact CE2-CE2 4.13Å; F48-Y315 AromaticContact CE2-CG 3.94Å; F48-Y315 HydrophobicContact CE2-CG 3.94Å; F48-Y315 AromaticContact CZ-CD1 3.7Å; F48-Y315 HydrophobicContact CZ-CD1 3.7Å; F48-Y315 AromaticContact CZ-CE1 3.92Å; F48-Y315 HydrophobicContact CZ-CE1 3.92Å; F48-Y315 HydrophobicContact CZ-CG 4.08Å; F59-Y315 HydrophobicContact CE1-CE1 4.18Å; F59-Y315 HydrophobicContact CZ-CD1 4.45Å; F59-Y315 AromaticContact CZ-CE1 3.99Å; F59-Y315 HydrophobicContact CZ-CE1 3.99Å; A63-Y315 HydrophobicContact CB-CE1 4.38Å; T252-Y315 HydrophobicContact CG2-CD1 3.64Å; T252-Y315 HydrophobicContact CG2-CE1 3.97Å; I256-Y315 HydrophobicContact CD1-CD1 4.45Å; I256-Y315 HydrophobicContact CD1-CE1 3.71Å; I256-Y315 HydrophobicContact CD1-CE2 4.37Å; D311-Y315 HydrophobicContact CB-CD2 4.35Å; D311-Y315 HydrophobicContact CB-CE2 4.02Å; D311-Y315 WeakPolarHBondContact O-CD2 3.35Å; D311-Y315 PolarHBondContact O-N 3.18Å; F312-Y315 PolarHBondContact O-N 2.98Å; Y315-L319 HydrophobicContact CD1-CD2 4.45Å; Y315-L319 WeakPolarHBondContact O-CA 3.3Å; Y315-L319 WeakPolarHBondContact O-CB 3.13Å; Y315-L319 PolarHBondContact O-N 3.08Å
316	W	96.6	Very high	95.6	Very high	110 Å²	110	36 Å²	36	42%	0.417	17%	0.169	S	C	.	.	H	α-helix	trans	-63.9	-42.5	177.2	-178.5	85.8	0	0	0	112.4	F312 F313 L314 F322 R323	F312-W316 VanDerWaalsContact O-CB 3.25Å; F312-W316 WeakPolarHBondContact O-CB 3.42Å; F312-W316 PolarHBondContact O-N 2.92Å; F313-W316 PolarHBondContact O-N 3.44Å; L314-W316 VanDerWaalsContact C-N 3.34Å; L314-W316 PolarHBondContact O-N 3.5Å; W316-F322 HydrophobicContact CB-CD1 4.35Å; W316-F322 HydrophobicContact CB-CE1 4.26Å; W316-R323 HydrophobicContact CG-CG 4.16Å; W316-R323 WeakPolarHBondContact O-CD 3.35Å; W316-R323 WeakPolarHBondContact O-CG 3.32Å
317	A	96.3	Very high	95.5	Very high	42 Å²	42	39.3 Å²	39.3	35%	0.347	18%	0.18	S	C	.	.	H	α-helix	trans	-69.2	-46.3	-178.4	0	0	0	0	0	112.6	F313 L314	F313-A317 WeakPolarHBondContact O-CB 3.39Å; F313-A317 PolarHBondContact O-N 2.74Å; L314-A317 PolarHBondContact O-N 3.05Å
318	F	94.8	Very high	95.4	Very high	64 Å²	64	44.2 Å²	44.2	28%	0.281	20%	0.201	S	C	.	.	H	α-helix	trans	-103.9	-13.2	-167	-63.6	-66.2	0	0	0	115	S248 I251 T252 A255 L314 P320	S248-F318 VanDerWaalsContact CB-O 3.26Å; S248-F318 WeakPolarHBondContact CB-O 3.3Å; S248-F318 PolarHBondContact OG-O 3.38Å; I251-F318 HydrophobicContact CG2-CB 4.47Å; I251-F318 HydrophobicContact CG2-CD1 3.74Å; I251-F318 HydrophobicContact CG2-CE1 4.25Å; I251-F318 HydrophobicContact CG2-CG 4.21Å; T252-F318 HydrophobicContact CG2-CB 4.36Å; T252-F318 WeakPolarHBondContact OG1-CB 3.45Å; A255-F318 HydrophobicContact CB-CD2 3.83Å; A255-F318 HydrophobicContact CB-CE2 3.62Å; A255-F318 HydrophobicContact CB-CZ 4.34Å; L314-F318 HydrophobicContact CD2-CD2 4.31Å; L314-F318 HydrophobicContact CD2-CE2 3.9Å; L314-F318 WeakPolarHBondContact O-CD2 3.48Å; L314-F318 PolarHBondContact O-N 2.79Å; F318-P320 WeakPolarHBondContact O-CD 3.47Å
319	L	94.5	Very high	95.3	Very high	4 Å²	4	45.9 Å²	45.9	2%	0.021	21%	0.209	C	C	.	.			trans	-112.6	97.9	-177.4	-162.4	61.8	0	0	0	111.9	F48 F59 K249 Y315 I321 F322 R323	F48-L319 HydrophobicContact CE1-CD2 3.93Å; F48-L319 HydrophobicContact CZ-CD2 3.85Å; F59-L319 HydrophobicContact CE1-CD2 3.72Å; F59-L319 HydrophobicContact CZ-CD2 4.12Å; K249-L319 HydrophobicContact CG-CD1 3.67Å; Y315-L319 HydrophobicContact CD1-CD2 4.45Å; Y315-L319 WeakPolarHBondContact O-CA 3.3Å; Y315-L319 WeakPolarHBondContact O-CB 3.13Å; Y315-L319 PolarHBondContact O-N 3.08Å; L319-I321 VanDerWaalsContact C-N 3.3Å; L319-I321 PolarHBondContact O-N 2.84Å; L319-F322 HydrophobicContact CB-CB 3.92Å; L319-F322 HydrophobicContact CD2-CB 3.96Å; L319-F322 HydrophobicContact CG-CB 4.02Å; L319-F322 WeakPolarHBondContact O-CB 3.39Å; L319-F322 PolarHBondContact O-N 3.42Å; L319-F322 VanDerWaalsContact O-N 3.09Å; L319-R323 PolarHBondContact O-N 3.09Å
320	P	93.2	Very high	95.2	Very high	14 Å²	14	49.3 Å²	49.3	9%	0.091	23%	0.226	C	C	.	.	H	α-helix	trans	-58.9	-38.9	-177.3	-22.5	30.5	0	0	0	113.6	Y244 S248 F318 F322 R323 Q324	Y244-P320 HydrophobicContact CE1-CG 3.73Å; S248-P320 WeakPolarHBondContact OG-CD 3.49Å; F318-P320 WeakPolarHBondContact O-CD 3.47Å; P320-F322 VanDerWaalsContact C-N 3.29Å; P320-F322 PolarHBondContact O-N 2.83Å; P320-R323 PolarHBondContact O-N 3.33Å; P320-Q324 WeakPolarHBondContact O-CG 3.25Å; P320-Q324 PolarHBondContact O-N 3.45Å
321	I	92.6	Very high	95	Very high	44 Å²	44	47 Å²	47	23%	0.226	22%	0.219	C	C	.	.	H	α-helix	trans	-60.6	-41.3	178.3	-65.2	169.1	0	0	0	110.4	L51 N245 L319 Q324 T325	L51-I321 HydrophobicContact CD1-CG2 4.16Å; L51-I321 HydrophobicContact CD2-CG2 3.58Å; N245-I321 HydrophobicContact CB-CD1 3.89Å; L319-I321 VanDerWaalsContact C-N 3.3Å; L319-I321 PolarHBondContact O-N 2.84Å; I321-Q324 PolarHBondContact O-N 3.41Å; I321-T325 PolarHBondContact O-N 3.35Å; I321-T325 PolarHBondContact O-OG1 3.47Å
322	F	95	Very high	94.8	Very high	0 Å²	0	52.1 Å²	52.1	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-61.3	-46.5	177.1	-177.2	-89.7	0	0	0	111.2	I44 I47 F48 F312 W316 L319 P320 Q324 T325 L326	I44-F322 HydrophobicContact CG1-CZ 4.49Å; I47-F322 HydrophobicContact CB-CD2 4.2Å; I47-F322 HydrophobicContact CB-CE2 3.72Å; I47-F322 HydrophobicContact CB-CZ 4.31Å; I47-F322 HydrophobicContact CG1-CE2 4.33Å; I47-F322 HydrophobicContact CG1-CZ 4.43Å; I47-F322 HydrophobicContact CG2-CD2 3.47Å; I47-F322 VanDerWaalsContact CG2-CD2 3.47Å; I47-F322 HydrophobicContact CG2-CE2 3.53Å; I47-F322 HydrophobicContact CG2-CG 4.18Å; I47-F322 HydrophobicContact CG2-CZ 4.29Å; F48-F322 HydrophobicContact CD2-CD2 4.39Å; F48-F322 HydrophobicContact CD2-CE2 4.2Å; F48-F322 HydrophobicContact CE1-CD2 4.38Å; F48-F322 AromaticContact CE2-CD2 3.82Å; F48-F322 HydrophobicContact CE2-CD2 3.82Å; F48-F322 AromaticContact CE2-CE2 3.83Å; F48-F322 HydrophobicContact CE2-CE2 3.83Å; F48-F322 AromaticContact CZ-CD2 3.81Å; F48-F322 HydrophobicContact CZ-CD2 3.81Å; F48-F322 HydrophobicContact CZ-CE2 4.3Å; F312-F322 HydrophobicContact CD2-CE1 4.11Å; F312-F322 AromaticContact CD2-CZ 3.83Å; F312-F322 HydrophobicContact CD2-CZ 3.83Å; F312-F322 AromaticContact CE2-CE1 3.81Å; F312-F322 HydrophobicContact CE2-CE1 3.81Å; F312-F322 AromaticContact CE2-CZ 3.77Å; F312-F322 HydrophobicContact CE2-CZ 3.77Å; F312-F322 HydrophobicContact CZ-CE1 4.42Å; W316-F322 HydrophobicContact CB-CD1 4.35Å; W316-F322 HydrophobicContact CB-CE1 4.26Å; L319-F322 HydrophobicContact CB-CB 3.92Å; L319-F322 HydrophobicContact CD2-CB 3.96Å; L319-F322 HydrophobicContact CG-CB 4.02Å; L319-F322 WeakPolarHBondContact O-CB 3.39Å; L319-F322 PolarHBondContact O-N 3.42Å; L319-F322 VanDerWaalsContact O-N 3.09Å; P320-F322 VanDerWaalsContact C-N 3.29Å; P320-F322 PolarHBondContact O-N 2.83Å; F322-Q324 PolarHBondContact O-N 3.5Å; F322-T325 PolarHBondContact O-N 3.36Å; F322-L326 HydrophobicContact CE1-CD2 4.33Å; F322-L326 VanDerWaalsContact O-CB 3.28Å; F322-L326 WeakPolarHBondContact O-CB 3.27Å; F322-L326 PolarHBondContact O-N 2.98Å
323	R	95.4	Very high	94.5	Very high	67 Å²	67	55.5 Å²	55.5	25%	0.253	26%	0.26	S	S	.	.	H	α-helix	trans	-59.7	-44.3	176.2	-66.3	-164.7	-68	-150.6	2.1	112.8	W316 L319 P320 L326 Y327	W316-R323 HydrophobicContact CG-CG 4.16Å; W316-R323 WeakPolarHBondContact O-CD 3.35Å; W316-R323 WeakPolarHBondContact O-CG 3.32Å; L319-R323 PolarHBondContact O-N 3.09Å; P320-R323 PolarHBondContact O-N 3.33Å; R323-L326 PolarHBondContact O-N 3.19Å; R323-Y327 WeakPolarHBondContact O-CB 3.37Å; R323-Y327 PolarHBondContact O-N 3.1Å
324	Q	94.5	Very high	94.2	Very high	84 Å²	84	56.8 Å²	56.8	39%	0.393	27%	0.27	S	S	.	.	H	α-helix	trans	-62.9	-44.4	179.6	-71.8	175.4	4.5	0	0	111.3	P320 I321 F322 Y327 K328	P320-Q324 WeakPolarHBondContact O-CG 3.25Å; P320-Q324 PolarHBondContact O-N 3.45Å; I321-Q324 PolarHBondContact O-N 3.41Å; F322-Q324 PolarHBondContact O-N 3.5Å; Q324-Y327 PolarHBondContact O-N 2.99Å; Q324-K328 WeakPolarHBondContact O-CG 3.35Å; Q324-K328 PolarHBondContact O-N 2.9Å
325	T	95.1	Very high	93.8	Very high	15 Å²	15	58.5 Å²	58.5	9%	0.092	28%	0.283	C	S	.	.	H	α-helix	trans	-68.3	-40.1	178	-60.2	0	0	0	0	111.9	I47 L50 L51 I321 F322 K328 F329	I47-T325 HydrophobicContact CD1-CG2 4.33Å; I47-T325 HydrophobicContact CG2-CG2 3.97Å; L50-T325 HydrophobicContact CB-CG2 4.31Å; L51-T325 HydrophobicContact CD2-CG2 4.18Å; L51-T325 VanDerWaalsContact CD2-OG1 3.23Å; L51-T325 WeakPolarHBondContact CD2-OG1 3.2Å; L51-T325 HydrophobicContact CG-CG2 4.24Å; I321-T325 PolarHBondContact O-N 3.35Å; I321-T325 PolarHBondContact O-OG1 3.47Å; F322-T325 PolarHBondContact O-N 3.36Å; T325-K328 PolarHBondContact O-N 2.98Å; T325-F329 WeakPolarHBondContact O-CB 3.37Å; T325-F329 PolarHBondContact O-N 3.23Å
326	L	95.3	Very high	93	Very high	14 Å²	14	62.4 Å²	62.4	7%	0.073	31%	0.305	C	S	.	.	H	α-helix	trans	-60.8	-46.8	174.2	-178.3	67	0	0	0	111.5	I47 F312 F322 R323 K328 F329 I330	I47-L326 HydrophobicContact CD1-CB 4.26Å; I47-L326 HydrophobicContact CD1-CD1 3.94Å; I47-L326 HydrophobicContact CG1-CB 4.5Å; I47-L326 HydrophobicContact CG1-CD1 3.99Å; F312-L326 HydrophobicContact CE2-CD2 4.24Å; F312-L326 HydrophobicContact CZ-CD2 3.82Å; F322-L326 HydrophobicContact CE1-CD2 4.33Å; F322-L326 VanDerWaalsContact O-CB 3.28Å; F322-L326 WeakPolarHBondContact O-CB 3.27Å; F322-L326 PolarHBondContact O-N 2.98Å; R323-L326 PolarHBondContact O-N 3.19Å; L326-K328 PolarHBondContact O-N 2.96Å; L326-F329 PolarHBondContact O-N 3.47Å; L326-I330 HydrophobicContact CD1-CD1 3.98Å; L326-I330 HydrophobicContact CD1-CG1 4.34Å; L326-I330 HydrophobicContact CG-CD1 3.85Å; L326-I330 WeakPolarHBondContact O-CG1 3.34Å; L326-I330 PolarHBondContact O-N 2.88Å
327	Y	94.9	Very high	92	Very high	121 Å²	121	65.2 Å²	65.2	48%	0.475	32%	0.32	S	S	.	.	H	α-helix	trans	-60.4	-46.6	176.6	-178.3	-100.7	0	0	0	111.6	R323 Q324 F329 I330 T331 Y402	R323-Y327 WeakPolarHBondContact O-CB 3.37Å; R323-Y327 PolarHBondContact O-N 3.1Å; Q324-Y327 PolarHBondContact O-N 2.99Å; Y327-F329 VanDerWaalsContact C-N 3.3Å; Y327-F329 PolarHBondContact O-N 2.98Å; Y327-I330 PolarHBondContact O-N 3.5Å; Y327-T331 WeakPolarHBondContact O-CB 3.29Å; Y327-T331 PolarHBondContact O-N 3.26Å; Y327-T331 PolarHBondContact O-OG1 3.43Å; Y327-Y402 HydrophobicContact CE1-CD1 4.08Å; Y327-Y402 AromaticContact CE1-CE1 3.86Å; Y327-Y402 HydrophobicContact CE1-CE1 3.86Å; Y327-Y402 AromaticContact CZ-CE1 3.95Å; Y327-Y402 WeakPolarHBondContact OH-CE1 3.14Å
328	K	94.5	Very high	90.9	Very high	108 Å²	108	67.2 Å²	67.2	47%	0.47	33%	0.33	S	S	.	.	H	α-helix	trans	-59.1	-41.8	175.5	-74.6	177.9	-179.9	-176	0	112	Q324 T325 L326 K332	Q324-K328 WeakPolarHBondContact O-CG 3.35Å; Q324-K328 PolarHBondContact O-N 2.9Å; T325-K328 PolarHBondContact O-N 2.98Å; L326-K328 PolarHBondContact O-N 2.96Å; K328-K332 WeakPolarHBondContact O-CB 3.41Å; K328-K332 PolarHBondContact O-N 3.3Å
329	F	93.3	Very high	89.6	Confident	46 Å²	46	69.1 Å²	69.1	20%	0.202	34%	0.343	C	S	.	.	H	α-helix	trans	-64.7	-48.8	178.6	179.6	-107	0	0	0	112	F43 I46 I47 L50 T325 L326 Y327 K332 L333	F43-F329 HydrophobicContact CE1-CE1 4.29Å; I46-F329 HydrophobicContact CG2-CE1 4.35Å; I46-F329 HydrophobicContact CG2-CE2 4.08Å; I46-F329 HydrophobicContact CG2-CZ 3.91Å; I47-F329 HydrophobicContact CD1-CB 3.93Å; I47-F329 HydrophobicContact CD1-CD1 4.19Å; I47-F329 HydrophobicContact CD1-CG 4.12Å; L50-F329 HydrophobicContact CD1-CD2 3.74Å; L50-F329 HydrophobicContact CD1-CE2 4.31Å; L50-F329 HydrophobicContact CD1-CG 4.35Å; T325-F329 WeakPolarHBondContact O-CB 3.37Å; T325-F329 PolarHBondContact O-N 3.23Å; L326-F329 PolarHBondContact O-N 3.47Å; Y327-F329 VanDerWaalsContact C-N 3.3Å; Y327-F329 PolarHBondContact O-N 2.98Å; F329-K332 PolarHBondContact O-N 3.44Å; F329-L333 HydrophobicContact CD1-CD1 3.87Å; F329-L333 HydrophobicContact CE1-CD1 3.37Å; F329-L333 HydrophobicContact CE1-CG 4.35Å; F329-L333 HydrophobicContact CE2-CD1 4.3Å; F329-L333 HydrophobicContact CZ-CD1 3.62Å; F329-L333 HydrophobicContact CZ-CG 4.26Å; F329-L333 WeakPolarHBondContact O-CG 3.49Å; F329-L333 PolarHBondContact O-N 3.02Å
330	I	93.4	Very high	88.5	Confident	73 Å²	73	77.2 Å²	77.2	37%	0.374	38%	0.378	S	S	.	.	H	α-helix	trans	-62.4	-46.8	177.8	-67.2	169.8	0	0	0	110.5	L326 Y327 K332 L333 L334	L326-I330 HydrophobicContact CD1-CD1 3.98Å; L326-I330 HydrophobicContact CD1-CG1 4.34Å; L326-I330 HydrophobicContact CG-CD1 3.85Å; L326-I330 WeakPolarHBondContact O-CG1 3.34Å; L326-I330 PolarHBondContact O-N 2.88Å; Y327-I330 PolarHBondContact O-N 3.5Å; I330-K332 VanDerWaalsContact C-N 3.32Å; I330-K332 PolarHBondContact O-N 3.41Å; I330-L333 PolarHBondContact O-N 3.07Å; I330-L333 VanDerWaalsContact O-N 3.16Å; I330-L334 HydrophobicContact CG2-CD1 3.81Å; I330-L334 HydrophobicContact CG2-CG 4.3Å; I330-L334 WeakPolarHBondContact O-CG 3.45Å; I330-L334 PolarHBondContact O-N 3.07Å
331	T	92.7	Very high	87.3	Confident	35 Å²	35	84.1 Å²	84.1	22%	0.215	41%	0.407	C	S	.	.	H	α-helix	trans	-60.2	-41.6	177.5	-60.3	0	0	0	0	111.2	Y327 L333 L334 C335	Y327-T331 WeakPolarHBondContact O-CB 3.29Å; Y327-T331 PolarHBondContact O-N 3.26Å; Y327-T331 PolarHBondContact O-OG1 3.43Å; T331-L333 PolarHBondContact O-N 3.29Å; T331-L334 PolarHBondContact O-N 3.3Å; T331-C335 VanDerWaalsContact O-CB 3.27Å; T331-C335 WeakPolarHBondContact O-CB 3.3Å; T331-C335 PolarHBondContact O-N 3.44Å; T331-C335 PolarHBondContact O-SG 3.13Å
332	K	91.4	Very high	86	Confident	110 Å²	110	91.7 Å²	91.7	48%	0.478	43%	0.432	S	S	.	.	H	α-helix	trans	-63	-41.2	175.2	-173.3	173.1	-179.8	173.7	0	112.3	K328 F329 I330 N336 Y394	K328-K332 WeakPolarHBondContact O-CB 3.41Å; K328-K332 PolarHBondContact O-N 3.3Å; F329-K332 PolarHBondContact O-N 3.44Å; I330-K332 VanDerWaalsContact C-N 3.32Å; I330-K332 PolarHBondContact O-N 3.41Å; K332-N336 VanDerWaalsContact O-CB 3.26Å; K332-N336 WeakPolarHBondContact O-CB 3.49Å; K332-N336 PolarHBondContact O-N 3.39Å; K332-Y394 PolarHBondContact NZ-OH 3.04Å
333	L	90.6	Very high	84.5	Confident	100 Å²	100	101.9 Å²	101.9	52%	0.524	47%	0.471	S	S	.	.	H	α-helix	trans	-63.9	-43	176	-75.1	172.8	0	0	0	112.1	F329 I330 T331	F329-L333 HydrophobicContact CD1-CD1 3.87Å; F329-L333 HydrophobicContact CE1-CD1 3.37Å; F329-L333 HydrophobicContact CE1-CG 4.35Å; F329-L333 HydrophobicContact CE2-CD1 4.3Å; F329-L333 HydrophobicContact CZ-CD1 3.62Å; F329-L333 HydrophobicContact CZ-CG 4.26Å; F329-L333 WeakPolarHBondContact O-CG 3.49Å; F329-L333 PolarHBondContact O-N 3.02Å; I330-L333 PolarHBondContact O-N 3.07Å; I330-L333 VanDerWaalsContact O-N 3.16Å; T331-L333 PolarHBondContact O-N 3.29Å
334	L	91.1	Very high	83.2	Confident	113 Å²	113	102.3 Å²	102.3	59%	0.592	48%	0.484	S	S	*	.	H	α-helix	trans	-70.1	-45.7	178.7	-66.7	174.5	0	0	0	111.9	I330 T331 K337	I330-L334 HydrophobicContact CG2-CD1 3.81Å; I330-L334 HydrophobicContact CG2-CG 4.3Å; I330-L334 WeakPolarHBondContact O-CG 3.45Å; I330-L334 PolarHBondContact O-N 3.07Å; T331-L334 PolarHBondContact O-N 3.3Å; L334-K337 WeakPolarHBondContact O-CB 3.21Å; L334-K337 PolarHBondContact O-N 3.33Å
335	C	88.2	Confident	81.7	Confident	63 Å²	63	104 Å²	104	43%	0.426	50%	0.496	S	S	.	.	H	α-helix	trans	-67.6	-35.5	179.9	-69.6	0	0	0	0	113.1	T331 K337 C338 N339	T331-C335 VanDerWaalsContact O-CB 3.27Å; T331-C335 WeakPolarHBondContact O-CB 3.3Å; T331-C335 PolarHBondContact O-N 3.44Å; T331-C335 PolarHBondContact O-SG 3.13Å; C335-K337 PolarHBondContact O-N 2.78Å; C335-C338 WeakPolarHBondContact O-CB 3.37Å; C335-C338 PolarHBondContact O-N 3Å; C335-N339 PolarHBondContact O-N 3.39Å; C335-N339 VanDerWaalsContact O-N 3.12Å
336	N	79.7	Confident	80.1	Confident	84 Å²	84	110.6 Å²	110.6	45%	0.449	53%	0.525	S	S	.	.	H	α-helix	trans	-63	-29.6	176.1	-81.3	-8.3	0	0	0	112.5	K332 C338 K340	K332-N336 VanDerWaalsContact O-CB 3.26Å; K332-N336 WeakPolarHBondContact O-CB 3.49Å; K332-N336 PolarHBondContact O-N 3.39Å; N336-C338 VanDerWaalsContact C-N 3.3Å; N336-C338 PolarHBondContact O-N 2.82Å; N336-K340 PolarHBondContact O-N 3.02Å
337	K	75.8	Confident	78.6	Confident	169 Å²	169	114.2 Å²	114.2	74%	0.735	55%	0.552	S	S	*	*	H	α-helix	trans	-67.2	-32.5	174.6	-153.2	172.5	-177.3	178	0	111.5	L334 C335	L334-K337 WeakPolarHBondContact O-CB 3.21Å; L334-K337 PolarHBondContact O-N 3.33Å; C335-K337 PolarHBondContact O-N 2.78Å
338	C	72	Confident	76.9	Confident	83 Å²	83	115.3 Å²	115.3	56%	0.561	57%	0.566	S	S	*	*	H	α-helix	trans	-73.4	-43.9	175.5	-62.9	0	0	0	0	112.7	C335 N336 K340 K341 R342	C335-C338 WeakPolarHBondContact O-CB 3.37Å; C335-C338 PolarHBondContact O-N 3Å; N336-C338 VanDerWaalsContact C-N 3.3Å; N336-C338 PolarHBondContact O-N 2.82Å; C338-K340 PolarHBondContact O-N 3.25Å; C338-K341 PolarHBondContact O-N 3.04Å; C338-R342 PolarHBondContact O-N 2.83Å
339	N	68.8	Low	75.3	Confident	105 Å²	105	117.7 Å²	117.7	56%	0.561	58%	0.578	S	S	*	*	H	α-helix	trans	-69.5	-33.8	-178	-77.8	-11.7	0	0	0	113	C335 K341 R342 R343	C335-N339 PolarHBondContact O-N 3.39Å; C335-N339 VanDerWaalsContact O-N 3.12Å; N339-K341 VanDerWaalsContact C-N 3.32Å; N339-K341 PolarHBondContact O-N 3.43Å; N339-R342 PolarHBondContact O-N 3.5Å; N339-R343 PolarHBondContact O-N 3.4Å
340	K	70.6	Confident	73.7	Confident	173 Å²	173	122.2 Å²	122.2	75%	0.752	61%	0.605	S	S	*	*	H	α-helix	trans	-64	-35.7	172.8	-86.3	-172.3	174.6	-176.5	0	112.6	N336 C338 R342 R343 S344	N336-K340 PolarHBondContact O-N 3.02Å; C338-K340 PolarHBondContact O-N 3.25Å; K340-R342 PolarHBondContact O-N 2.89Å; K340-R343 PolarHBondContact O-N 2.85Å; K340-S344 PolarHBondContact O-N 3.43Å
341	K	69.3	Low	72.2	Confident	159 Å²	159	125.9 Å²	125.9	69%	0.691	63%	0.625	S	S	*	*	H	α-helix	trans	-67.6	-33.8	178.5	-160.6	172	-177	179.6	0	112.4	C338 N339	C338-K341 PolarHBondContact O-N 3.04Å; N339-K341 VanDerWaalsContact C-N 3.32Å; N339-K341 PolarHBondContact O-N 3.43Å
342	R	64.2	Low	70.7	Confident	203 Å²	203	131.1 Å²	131.1	77%	0.766	65%	0.652	S	S	*	*	H	α-helix	trans	-70.1	-38.2	175	-89.9	-175.9	170.9	166.9	-3.1	113.5	C338 N339 K340 N345	C338-R342 PolarHBondContact O-N 2.83Å; N339-R342 PolarHBondContact O-N 3.5Å; K340-R342 PolarHBondContact O-N 2.89Å; R342-N345 PolarHBondContact O-N 3.47Å
343	R	64	Low	69.3	Low	215 Å²	215	133.7 Å²	133.7	81%	0.811	67%	0.671	S	S	*	*	H	α-helix	trans	-68.3	-33.3	178.1	-82.6	-174.2	171.7	174.2	-2.5	113.2	N339 K340 N345 H346	N339-R343 PolarHBondContact O-N 3.4Å; K340-R343 PolarHBondContact O-N 2.85Å; R343-N345 VanDerWaalsContact C-N 3.32Å; R343-N345 PolarHBondContact O-N 3.17Å; R343-H346 PolarHBondContact O-N 2.75Å
344	S	67.8	Low	67.8	Low	76 Å²	76	133.8 Å²	133.8	53%	0.531	68%	0.68	S	S	.	*	H	α-helix	trans	-64.4	-33.5	176.6	-174.2	0	0	0	0	113.3	K340	K340-S344 PolarHBondContact O-N 3.43Å
345	N	63	Low	66.2	Low	118 Å²	118	136.3 Å²	136.3	63%	0.631	69%	0.694	S	S	*	*	H	α-helix	trans	-80.3	-23.2	-178.5	-76.3	4.2	0	0	0	113.1	R342 R343	R342-N345 PolarHBondContact O-N 3.47Å; R343-N345 VanDerWaalsContact C-N 3.32Å; R343-N345 PolarHBondContact O-N 3.17Å
346	H	62.3	Low	64.6	Low	155 Å²	155	138.8 Å²	138.8	72%	0.718	71%	0.712	S	S	*	*	H	α-helix	trans	-81.4	-23.5	179.3	-128.8	-39.4	0	0	0	113.4	R343 N348	R343-H346 PolarHBondContact O-N 2.75Å; H346-N348 VanDerWaalsContact C-N 3.35Å
347	S	62.3	Low	63.3	Low	90 Å²	90	143.7 Å²	143.7	63%	0.629	73%	0.734	S	S	*	*	T	Hydrogen-bonded Turn	trans	-72.3	-23.9	177.8	-176	0	0	0	0	113.7
348	N	60.7	Low	62.2	Low	143 Å²	143	143 Å²	143	77%	0.765	74%	0.739	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.1	-5	-177.9	-87.4	1.8	0	0	0	114.2	H346	H346-N348 VanDerWaalsContact C-N 3.35Å
349	H	60.7	Low	61.3	Low	158 Å²	158	146.8 Å²	146.8	73%	0.731	75%	0.75	S	S	*	*	S	Bend	trans	-99.3	-6.4	-178.3	-120.5	-53.7	0	0	0	115.2
350	N	60.1	Low	60.3	Low	141 Å²	141	147.7 Å²	147.7	75%	0.754	76%	0.755	S	S	*	*	S	Bend	trans	-97.6	5.4	-175.4	-107.8	14.7	0	0	0	115.7
351	N	60.4	Low	59.4	Low	150 Å²	150	144.5 Å²	144.5	80%	0.802	75%	0.75	S	S	*	*	S	Bend	trans	-98.1	6.7	179	-101.5	5.4	0	0	0	115.5
352	N	62.6	Low	58.7	Low	145 Å²	145	143.4 Å²	143.4	78%	0.775	75%	0.752	S	S	*	*	S	Bend	trans	-116.9	3.8	-174.9	-81	3	0	0	0	116.9
353	N	61.4	Low	58.4	Low	164 Å²	164	140.3 Å²	140.3	88%	0.877	75%	0.751	S	S	*	*			trans	-125.3	28.4	-175.6	-91.4	5.8	0	0	0	115.9	N355	N353-N355 PolarHBondContact O-N 2.88Å
354	S	58.5	Low	57.8	Low	103 Å²	103	137.4 Å²	137.4	72%	0.72	75%	0.751	S	S	*	*			trans	-93	76.2	168.6	-51	0	0	0	0	109.4
355	N	58.6	Low	57.1	Low	166 Å²	166	137.6 Å²	137.6	89%	0.888	77%	0.765	S	S	*	*			trans	-176	85.3	162.8	-88.1	-22.3	0	0	0	111.7	N353	N353-N355 PolarHBondContact O-N 2.88Å
356	S	53.8	Low	56.7	Low	115 Å²	115	139.3 Å²	139.3	80%	0.804	77%	0.774	S	S	*	*			trans	176	92.7	144.5	48.7	0	0	0	0	108
357	M	53.2	Low	56.5	Low	186 Å²	186	140.3 Å²	140.3	92%	0.916	78%	0.782	S	S	*	*				47.3	97.1	104.6	-73.5	-167.8	-165.5	0	0	113.3
358	N	52.6	Low	55.9	Low	156 Å²	156	142.2 Å²	142.2	83%	0.834	79%	0.789	S	S	*	*				58.4	110.5	93.5	-102.8	-6.5	0	0	0	114.2
359	M	52.7	Low	55.4	Low	161 Å²	161	142.8 Å²	142.8	79%	0.793	79%	0.791	S	S	*	*				177.8	134.7	110.1	-91.1	-132.5	-177.7	0	0	112.9
360	N	48.4	Very low	55.4	Low	124 Å²	124	140.4 Å²	140.4	66%	0.663	79%	0.79	S	S	*	*			trans	66.6	107.4	138.5	-70.1	1.6	0	0	0	120.1
361	T	51.7	Low	55.3	Low	106 Å²	106	139.9 Å²	139.9	65%	0.65	79%	0.787	S	S	*	*				85.3	124.9	68.5	56.3	0	0	0	0	115.5
362	N	54.1	Low	55.2	Low	136 Å²	136	138.9 Å²	138.9	73%	0.727	78%	0.782	S	S	*	*			trans	72.7	115.3	141.7	-66.2	-3.6	0	0	0	120
363	N	58.4	Low	54.9	Low	139 Å²	139	137.6 Å²	137.6	74%	0.743	78%	0.775	S	S	*	*				171.9	125.3	93.2	-97.7	-26.4	0	0	0	113.6
364	N	51.3	Low	54.8	Low	154 Å²	154	137 Å²	137	82%	0.824	77%	0.771	S	S	*	*			trans	31.8	129.7	134.5	-63.7	-13.7	0	0	0	122.3
365	G	52.3	Low	54.9	Low	80 Å²	80	136.5 Å²	136.5	83%	0.825	77%	0.768	S	S	*	*			trans	-165.4	96.8	158.4	0	0	0	0	0	111.9
366	N	53.8	Low	54.5	Low	154 Å²	154	135.7 Å²	135.7	82%	0.824	76%	0.764	S	S	*	*			trans	-62.7	153.7	177.5	-66.2	-36.6	0	0	0	113.7
367	M	58.1	Low	54.6	Low	176 Å²	176	138.8 Å²	138.8	87%	0.867	77%	0.765	S	S	*	*				173.7	124.7	115.6	-98.2	-158.9	179	0	0	114.7
368	V	50.9	Low	54.2	Low	129 Å²	129	140.1 Å²	140.1	78%	0.782	76%	0.76	S	S	*	*				84	99.6	128	-176.9	0	0	0	0	120.2
369	L	50.9	Low	53.9	Low	156 Å²	156	139.2 Å²	139.2	82%	0.817	75%	0.754	S	S	*	*			trans	-62.1	-171.9	148.2	-93.8	127.6	0	0	0	112.4
370	P	59	Low	53.9	Low	107 Å²	107	137.7 Å²	137.7	70%	0.695	75%	0.748	S	S	*	*			cis	-131.2	-173.1	1.8	26.4	0.7	0	0	0	111.3
371	N	57.9	Low	53.9	Low	130 Å²	130	138.3 Å²	138.3	70%	0.695	75%	0.751	S	S	*	*				169.9	150.2	57	-165.8	6.8	0	0	0	108.2
372	N	58.4	Low	53.7	Low	130 Å²	130	141 Å²	141	70%	0.695	76%	0.761	S	S	*	*				138.9	89.8	130	-141.7	16.3	0	0	0	115.5
373	N	57.1	Low	53.1	Low	118 Å²	118	140 Å²	140	63%	0.631	76%	0.763	S	S	*	*			trans	26.3	123.9	130.1	-55.8	-24	0	0	0	120.3
374	N	58.8	Low	52.8	Low	151 Å²	151	142.2 Å²	142.2	81%	0.807	77%	0.771	S	S	*	*				177	135.1	93.8	-103.7	-18.5	0	0	0	115.4
375	S	60.6	Low	52.5	Low	93 Å²	93	140.7 Å²	140.7	65%	0.65	76%	0.763	S	S	*	*			trans	69	102.2	141.7	58.5	0	0	0	0	123.6
376	N	51.4	Low	52.3	Low	149 Å²	149	143.2 Å²	143.2	80%	0.797	76%	0.758	S	S	*	*				64	107.9	111.9	-56.5	-17.8	0	0	0	122.5
377	H	55.4	Low	51.9	Low	179 Å²	179	143.5 Å²	143.5	83%	0.829	76%	0.759	S	S	*	*				168.2	107.2	115.8	-103.8	-80.8	0	0	0	109.2
378	R	45.3	Very low	51.3	Low	215 Å²	215	142.3 Å²	142.3	81%	0.811	76%	0.756	S	S	*	*				44.5	123.5	93.3	-83.8	-168.5	178.3	179.7	1.6	112.8
379	L	46	Very low	51.1	Low	137 Å²	137	144.7 Å²	144.7	72%	0.717	76%	0.758	S	S	*	*			cis	-175.9	150.8	32.6	-104.8	154	0	0	0	110.7
380	I	52.3	Low	50.8	Low	128 Å²	128	144.9 Å²	144.9	66%	0.656	76%	0.755	S	S	*	*			trans	84.9	101	144	-60	160.7	0	0	0	120.9
381	D	48.9	Very low	50.1	Low	137 Å²	137	147.9 Å²	147.9	73%	0.733	76%	0.759	S	S	*	*				49.7	113.6	122.6	-47.2	-29.4	0	0	0	123
382	N	47.3	Very low	49.6	Very low	162 Å²	162	150.4 Å²	150.4	87%	0.866	76%	0.76	S	S	*	*				177.5	131	106.5	-109.3	-21	0	0	0	111.8
383	P	41.5	Very low	48.8	Very low	117 Å²	117	151.1 Å²	151.1	76%	0.76	76%	0.764	S	S	*	*			trans	-115.8	115.9	169.3	34.6	-20.2	0	0	0	112.1
384	M	50.9	Low	48.3	Very low	184 Å²	184	153.6 Å²	153.6	91%	0.906	77%	0.766	S	S	*	*			trans	-166.8	142.2	161.4	-87.1	-144.5	171.3	0	0	106.4
385	N	46.5	Very low	47.5	Very low	123 Å²	123	152.4 Å²	152.4	66%	0.658	76%	0.759	S	S	*	*			cis	-172.8	139.2	-3.9	-170.1	2.7	0	0	0	104
386	N	46.6	Very low	47	Very low	133 Å²	133	154.9 Å²	154.9	71%	0.711	76%	0.764	S	S	*	*			trans	17.7	121.6	157.5	-63.3	-20.1	0	0	0	120
387	N	47.2	Very low	46.6	Very low	159 Å²	159	151.9 Å²	151.9	85%	0.85	76%	0.755	S	S	*	*				-168.3	124	118.5	-90.4	-29.1	0	0	0	112.1	H389	N387-H389 PolarHBondContact O-N 3.46Å
388	D	43.7	Very low	45.9	Very low	151 Å²	151	149.9 Å²	149.9	81%	0.807	75%	0.75	S	S	*	*			trans	-60.3	116.6	179.1	-69.6	-54.2	0	0	0	113.1
389	H	46.6	Very low	45.7	Very low	179 Å²	179	145.2 Å²	145.2	83%	0.829	74%	0.74	S	S	*	*			trans	-116.7	95.5	156.9	-91.3	-42.7	0	0	0	109.6	N387 H391	N387-H389 PolarHBondContact O-N 3.46Å; H389-H391 VanDerWaalsContact C-N 3.34Å; H389-H391 PolarHBondContact O-N 2.92Å
390	H	44.6	Very low	45.1	Very low	161 Å²	161	143.8 Å²	143.8	75%	0.745	74%	0.742	S	S	*	*			trans	-61.4	92.3	165.8	-88.4	-61.3	0	0	0	110.5	Y392	H390-Y392 PolarHBondContact O-N 2.53Å
391	H	46.2	Very low	44.1	Very low	170 Å²	170	143.1 Å²	143.1	79%	0.787	75%	0.748	S	S	*	*			trans	-76.6	103.5	161.3	-105.8	-80.5	0	0	0	109	H389 N393	H389-H391 VanDerWaalsContact C-N 3.34Å; H389-H391 PolarHBondContact O-N 2.92Å; H391-N393 PolarHBondContact O-N 3.2Å; H391-N393 VanDerWaalsContact O-N 3.08Å
392	Y	45.8	Very low	43.6	Very low	182 Å²	182	142.7 Å²	142.7	71%	0.714	74%	0.737	S	S	*	*			trans	-74	92.5	165	-79.5	-79.7	0	0	0	109.1	H390 Y394	H390-Y392 PolarHBondContact O-N 2.53Å; Y392-Y394 PolarHBondContact O-N 3.37Å
393	N	41.5	Very low	42.8	Very low	146 Å²	146	141.1 Å²	141.1	78%	0.781	74%	0.739	S	S	*	*			trans	-69.4	111.2	161.5	-108.5	-6	0	0	0	108.1	H391 D395	H391-N393 PolarHBondContact O-N 3.2Å; H391-N393 VanDerWaalsContact O-N 3.08Å; N393-D395 PolarHBondContact O-N 3.34Å
394	Y	47.2	Very low	42.7	Very low	169 Å²	169	142.9 Å²	142.9	66%	0.663	73%	0.731	S	S	*	*			trans	-85.9	92.1	170.6	-85.4	-79	0	0	0	108.6	K332 Y392 I396	K332-Y394 PolarHBondContact NZ-OH 3.04Å; Y392-Y394 PolarHBondContact O-N 3.37Å; Y394-I396 PolarHBondContact O-N 3.23Å
395	D	41.3	Very low	41.9	Very low	126 Å²	126	142.2 Å²	142.2	67%	0.674	73%	0.728	S	S	*	*			trans	-67.3	119.7	165.1	-95	-37.9	0	0	0	109.9	N393 S397	N393-D395 PolarHBondContact O-N 3.34Å; D395-S397 VanDerWaalsContact C-N 3.25Å; D395-S397 PolarHBondContact O-N 2.93Å
396	I	51.5	Low	41.6	Very low	145 Å²	145	142.7 Å²	142.7	74%	0.744	73%	0.73	S	S	*	*	G	3₁₀ helix	trans	-84.8	2.6	-178.1	-86.7	172.4	0	0	0	111.9	Y394	Y394-I396 PolarHBondContact O-N 3.23Å
397	S	43.2	Very low	41	Very low	87 Å²	87	143.3 Å²	143.3	61%	0.608	73%	0.727	S	S	*	*	G	3₁₀ helix	trans	-79	-18.2	-174.6	43.5	0	0	0	0	115.5	D395 L399	D395-S397 VanDerWaalsContact C-N 3.25Å; D395-S397 PolarHBondContact O-N 2.93Å; S397-L399 PolarHBondContact O-N 3.45Å
398	D	40.8	Very low	40.5	Very low	137 Å²	137	141 Å²	141	73%	0.733	72%	0.721	S	S	*	*	G	3₁₀ helix	trans	-95.4	17.9	-168.2	-74.4	-4.3	0	0	0	116
399	L	40.1	Very low	40.5	Very low	116 Å²	116	140.1 Å²	140.1	61%	0.607	72%	0.715	S	S	*	*			trans	-104.8	58.3	176.8	-105.7	80.3	0	0	0	113.1	S397 C401 Y402	S397-L399 PolarHBondContact O-N 3.45Å; L399-C401 PolarHBondContact O-N 3.32Å; L399-Y402 HydrophobicContact CD2-CD2 3.71Å; L399-Y402 HydrophobicContact CD2-CE2 3.47Å; L399-Y402 VanDerWaalsContact CD2-CE2 3.47Å; L399-Y402 HydrophobicContact CG-CD2 4.18Å; L399-Y402 HydrophobicContact CG-CE2 3.88Å
400	S	32.5	Very low	40	Very low	107 Å²	107	134.4 Å²	134.4	75%	0.748	71%	0.705	S	S	*	*			trans	-85	67.6	169.3	61.2	0	0	0	0	111.3
401	C	32.3	Very low	39.9	Very low	115 Å²	115	134.8 Å²	134.8	78%	0.777	70%	0.701	S	S	*	*			trans	178.1	66.2	163.2	-103.2	0	0	0	0	112.1	L399	L399-C401 PolarHBondContact O-N 3.32Å
402	Y	37.4	Very low	39.5	Very low	127 Å²	127	133.2 Å²	133.2	50%	0.498	70%	0.697	S	S	.	*			trans	-136.4	104.8	164.5	-73.9	-73.6	0	0	0	110.8	Y327 L399 Y404	Y327-Y402 HydrophobicContact CE1-CD1 4.08Å; Y327-Y402 AromaticContact CE1-CE1 3.86Å; Y327-Y402 HydrophobicContact CE1-CE1 3.86Å; Y327-Y402 AromaticContact CZ-CE1 3.95Å; Y327-Y402 WeakPolarHBondContact OH-CE1 3.14Å; L399-Y402 HydrophobicContact CD2-CD2 3.71Å; L399-Y402 HydrophobicContact CD2-CE2 3.47Å; L399-Y402 VanDerWaalsContact CD2-CE2 3.47Å; L399-Y402 HydrophobicContact CG-CD2 4.18Å; L399-Y402 HydrophobicContact CG-CE2 3.88Å; Y402-Y404 PolarHBondContact O-N 3.24Å
403	S	32.2	Very low	39.1	Very low	130 Å²	130	131 Å²	131	91%	0.909	70%	0.697	S	S	*	*			trans	-63.8	122.1	174.7	-153.5	0	0	0	0	109.4	M405	S403-M405 PolarHBondContact O-N 3.07Å
404	Y	38.4	Very low	39	Very low	153 Å²	153	133 Å²	133	60%	0.6	70%	0.7	S	S	*	*			trans	-68.2	118	-176.8	-83.4	-108	0	0	0	110.5	Y402 N406	Y402-Y404 PolarHBondContact O-N 3.24Å; Y404-N406 PolarHBondContact O-N 3.48Å
405	M	34.8	Very low	38.6	Very low	171 Å²	171	130.5 Å²	130.5	84%	0.842	70%	0.702	S	S	*	*			trans	-68.8	81.2	154.6	-83.1	-90.8	-163.7	0	0	108	S403 F407	S403-M405 PolarHBondContact O-N 3.07Å; M405-F407 PolarHBondContact O-N 3.2Å; M405-F407 VanDerWaalsContact O-N 3.11Å
406	N	39.4	Very low	38.4	Very low	132 Å²	132	133.8 Å²	133.8	71%	0.706	71%	0.713	S	S	*	*			trans	-70.2	98.8	165	-78.2	-26	0	0	0	107.4	Y404 P408	Y404-N406 PolarHBondContact O-N 3.48Å; N406-P408 WeakPolarHBondContact O-CD 3.01Å
407	F	34.9	Very low	38	Very low	146 Å²	146	138.3 Å²	138.3	64%	0.64	72%	0.72	S	S	*	*			trans	-62.4	120.9	161.6	-116.3	-90	0	0	0	107.3	M405 L409	M405-F407 PolarHBondContact O-N 3.2Å; M405-F407 VanDerWaalsContact O-N 3.11Å; F407-L409 VanDerWaalsContact C-N 3.35Å; F407-L409 PolarHBondContact O-N 2.72Å
408	P	35.6	Very low	37.8	Very low	111 Å²	111	146.3 Å²	146.3	72%	0.721	74%	0.737	S	S	*	*			trans	-73.1	98.6	172.8	30.4	-28.6	0	0	0	106.2	N406 G410	N406-P408 WeakPolarHBondContact O-CD 3.01Å; P408-G410 PolarHBondContact O-N 3.05Å
409	L	43.5	Very low	38.1	Very low	133 Å²	133	143.5 Å²	143.5	70%	0.696	74%	0.741	S	S	*	*			trans	-68.9	76.6	150.5	-84.4	160.8	0	0	0	105.8	F407 Y411	F407-L409 VanDerWaalsContact C-N 3.35Å; F407-L409 PolarHBondContact O-N 2.72Å; L409-Y411 PolarHBondContact O-N 3.06Å; L409-Y411 VanDerWaalsContact O-N 3.09Å
410	G	36.7	Very low	38.1	Very low	59 Å²	59	150.5 Å²	150.5	61%	0.608	76%	0.759	S	S	*	*			trans	-56.9	112.7	170.5	0	0	0	0	0	107.4	P408 I412	P408-G410 PolarHBondContact O-N 3.05Å; G410-I412 PolarHBondContact O-N 3Å
411	Y	43.3	Very low	38.5	Very low	169 Å²	169	148.9 Å²	148.9	66%	0.663	76%	0.76	S	S	*	*			trans	-51.2	112.6	165.1	-106.7	-93.7	0	0	0	107.7	L409 D413	L409-Y411 PolarHBondContact O-N 3.06Å; L409-Y411 VanDerWaalsContact O-N 3.09Å; Y411-D413 VanDerWaalsContact C-N 3.34Å; Y411-D413 PolarHBondContact O-N 3.28Å
412	I	37.7	Very low	38.8	Very low	136 Å²	136	155 Å²	155	70%	0.697	77%	0.766	S	S	*	*			trans	-70.7	98.2	168	-57.4	175.4	0	0	0	106	G410 F414	G410-I412 PolarHBondContact O-N 3Å; I412-F414 HydrophobicContact CG2-CD2 3.36Å; I412-F414 HydrophobicContact CG2-CE2 3.48Å; I412-F414 VanDerWaalsContact CG2-CE2 3.48Å; I412-F414 HydrophobicContact CG2-CG 4.34Å; I412-F414 PolarHBondContact O-N 3.27Å
413	D	37.1	Very low	38.8	Very low	135 Å²	135	154.9 Å²	154.9	72%	0.722	78%	0.783	S	S	*	*			trans	-82.8	92.2	175.1	-153.3	4.6	0	0	0	109	Y411 T415	Y411-D413 VanDerWaalsContact C-N 3.34Å; Y411-D413 PolarHBondContact O-N 3.28Å; D413-T415 PolarHBondContact O-N 3.17Å; D413-T415 VanDerWaalsContact O-N 3.08Å
414	F	38.6	Very low	39	Very low	190 Å²	190	154.5 Å²	154.5	83%	0.833	78%	0.78	S	S	*	*			trans	-81	61	174.7	-99.8	-74.6	0	0	0	111	I412	I412-F414 HydrophobicContact CG2-CD2 3.36Å; I412-F414 HydrophobicContact CG2-CE2 3.48Å; I412-F414 VanDerWaalsContact CG2-CE2 3.48Å; I412-F414 HydrophobicContact CG2-CG 4.34Å; I412-F414 PolarHBondContact O-N 3.27Å
415	T	40.2	Very low	38.9	Very low	115 Å²	115	152.2 Å²	152.2	71%	0.706	78%	0.783	S	S	*	*			trans	-147.8	74.6	163.9	49.5	0	0	0	0	111.9	D413	D413-T415 PolarHBondContact O-N 3.17Å; D413-T415 VanDerWaalsContact O-N 3.08Å
416	H	37	Very low	39.1	Very low	196 Å²	196	152.8 Å²	152.8	91%	0.907	78%	0.784	S	S	*	*			trans	-96.1	90.5	164.4	-126.6	-45.7	0	0	0	109.8
417	R	41.4	Very low	39	Very low	239 Å²	239	151.4 Å²	151.4	90%	0.902	78%	0.784	S	S	*	*			trans	-88	138.2	156.7	-109.9	-173.4	-174.2	-170.9	2.8	108.7
418	R	40.6	Very low	39	Very low	255 Å²	255	151.6 Å²	151.6	96%	0.962	79%	0.791	S	S	*	*			trans	-55.2	134.5	-175.8	-63.9	171	176.3	173.8	-3	112.6
419	G	45.5	Very low	39.2	Very low	79 Å²	79	155.5 Å²	155.5	81%	0.814	79%	0.793	S	S	*	*			trans	-167.4	113.8	166.1	0	0	0	0	0	110.2
420	R	41.7	Very low	38.9	Very low	263 Å²	263	157.8 Å²	157.8	99%	0.992	79%	0.794	S	S	*	*			trans	-80.1	151.2	-172.3	-65.7	174.8	176.6	177	-2	112.2
421	G	39.6	Very low	39	Very low	73 Å²	73	166.1 Å²	166.1	75%	0.753	81%	0.808	S	S	*	*			trans	132.3	84.9	158.4	0	0	0	0	0	113.1
422	R	38.9	Very low	38.9	Very low	244 Å²	244	165 Å²	165	92%	0.921	81%	0.809	S	S	*	*				51.9	101.3	97	-76.7	-163.4	-164.2	-176.6	5.7	115
423	C	37.5	Very low	38.9	Very low	124 Å²	124	166.3 Å²	166.3	84%	0.838	81%	0.812	S	S	*	*				166.8	123	99	-89.9	0	0	0	0	113.4
424	S	37.3	Very low	39.2	Very low	121 Å²	121	169.7 Å²	169.7	85%	0.846	82%	0.816	S	S	*	*			trans	38.5	144.2	151.7	-99.6	0	0	0	0	126.1
425	P	35.9	Very low	39.7	Very low	105 Å²	105	172.7 Å²	172.7	68%	0.682	82%	0.822	S	S	*	*			trans	-99.5	157.4	178.8	40.2	-32.1	0	0	0	113
426	H	39.2	Very low	40.1	Very low	184 Å²	184	174.7 Å²	174.7	85%	0.852	82%	0.823	S	S	*	*			trans	176.4	147.1	138.9	-108.1	-84.9	0	0	0	112.7
427	S	37.9	Very low	40.4	Very low	102 Å²	102	176.5 Å²	176.5	71%	0.713	82%	0.822	S	S	*	*			trans	69.2	114.2	159	63.5	0	0	0	0	119.1
428	L	34.6	Very low	40.9	Very low	151 Å²	151	174.1 Å²	174.1	79%	0.791	82%	0.821	S	S	*	*				76.3	132.7	78.2	-103.8	163.5	0	0	0	114.3
429	Y	39	Very low	41	Very low	193 Å²	193	173.1 Å²	173.1	76%	0.757	82%	0.817	S	S	*	*			trans	105	112.9	163.9	-72.6	-86.4	0	0	0	120.2
430	Y	37	Very low	41.4	Very low	181 Å²	181	178 Å²	178	71%	0.71	82%	0.818	S	S	*	*			trans	43.3	127.6	130.9	-89.4	-101	0	0	0	120.4
431	Y	39.5	Very low	41.6	Very low	233 Å²	233	173.1 Å²	173.1	91%	0.914	81%	0.806	S	S	*	*			trans	-152.9	124.3	136.9	-114.2	-79.6	0	0	0	112.7
432	Q	41.6	Very low	42.1	Very low	146 Å²	146	177.5 Å²	177.5	68%	0.682	81%	0.807	S	S	*	*			trans	-118.8	139.1	177.1	-174.5	174.9	-5.2	0	0	107.4
433	H	38	Very low	42.5	Very low	163 Å²	163	173 Å²	173	76%	0.755	80%	0.796	S	S	*	*			trans	50.4	124	158.6	-96.9	-83.8	0	0	0	121.8
434	Y	42.4	Very low	43	Very low	206 Å²	206	174.1 Å²	174.1	81%	0.808	79%	0.789	S	S	*	*			trans	-155.4	120.4	143.6	-108.1	-81.3	0	0	0	111.9
435	R	48.4	Very low	43.4	Very low	253 Å²	253	175.3 Å²	175.3	96%	0.955	78%	0.781	S	S	*	*			trans	-157.5	100.8	148.8	-134.9	179.7	-170.1	178	3.9	110
436	H	48.8	Very low	43.8	Very low	158 Å²	158	177.2 Å²	177.2	73%	0.731	78%	0.781	S	S	*	*			trans	-98	139.1	174.5	-110.8	-73.1	0	0	0	110.6
437	R	43.1	Very low	43.9	Very low	234 Å²	234	178.7 Å²	178.7	88%	0.883	78%	0.778	S	S	*	*			trans	-86	146.3	158.1	-92.6	-179.9	178.4	173.3	1	108.8
438	H	52.1	Low	44.2	Very low	189 Å²	189	181.7 Å²	181.7	88%	0.875	78%	0.781	S	S	*	*			trans	-159.4	135.3	136.8	-101.2	-72.8	0	0	0	111.4
439	R	43.2	Very low	44.6	Very low	234 Å²	234	183.3 Å²	183.3	88%	0.883	78%	0.778	S	S	*	*			trans	-88.5	156.8	169.4	-81.5	177	170.3	171.4	-4.1	109.7
440	Q	54.5	Low	44.8	Very low	180 Å²	180	184.7 Å²	184.7	84%	0.841	78%	0.783	S	S	*	*			trans	176	113.7	134.2	-93.7	175.4	-4.1	0	0	109.5
441	H	44.8	Very low	45	Very low	161 Å²	161	184 Å²	184	75%	0.745	79%	0.787	S	S	*	*				77.6	113.7	106.5	-80.5	-55.4	0	0	0	116.9
442	H	50.7	Low	45.3	Very low	165 Å²	165	183.6 Å²	183.6	76%	0.764	79%	0.785	S	S	*	*				169	133.8	111.8	-94.4	-72.8	0	0	0	113.8
443	H	47.8	Very low	45.4	Very low	151 Å²	151	184 Å²	184	70%	0.699	79%	0.786	S	S	*	*			trans	9.2	154.6	146.4	-70.8	-63.3	0	0	0	121.1
444	Q	47.4	Very low	45.8	Very low	147 Å²	147	185.1 Å²	185.1	69%	0.687	79%	0.792	S	S	*	*			cis	172.6	164.7	-6.7	-168	171.3	13.3	0	0	105.5
445	H	46.6	Very low	45.8	Very low	145 Å²	145	180 Å²	180	67%	0.671	78%	0.784	S	S	*	*			trans	97.9	96.8	165.3	-70.9	-90.1	0	0	0	122
446	H	44.3	Very low	45.7	Very low	146 Å²	146	178.2 Å²	178.2	68%	0.676	78%	0.779	S	S	*	*				69.7	127.2	114.8	-83.8	-73.9	0	0	0	125.6
447	R	41.5	Very low	45.4	Very low	214 Å²	214	179.1 Å²	179.1	81%	0.808	78%	0.783	S	S	*	*			trans	86.1	102.8	135.7	-75.3	-176.1	-172.2	-169.5	2.9	121.6
448	H	42.3	Very low	45.4	Very low	165 Å²	165	176.7 Å²	176.7	76%	0.764	78%	0.782	S	S	*	*				46.5	139.4	114.4	-81.3	-75.5	0	0	0	123.9
449	Y	43.8	Very low	44.7	Very low	186 Å²	186	173.8 Å²	173.8	73%	0.729	78%	0.781	S	S	*	*			trans	90.6	106.2	154	-73.7	-75.2	0	0	0	119.3
450	Y	44.1	Very low	44.5	Very low	221 Å²	221	171.7 Å²	171.7	87%	0.867	78%	0.782	S	S	*	*				171	156.6	98.1	-97.6	-75.1	0	0	0	111.7
451	Q	41.3	Very low	43.8	Very low	167 Å²	167	173.5 Å²	173.5	78%	0.78	78%	0.781	S	S	*	*			trans	-116.7	141.8	-160.7	171.8	-175.7	-0.4	0	0	108.8
452	Y	44.7	Very low	43.4	Very low	225 Å²	225	175.9 Å²	175.9	88%	0.882	79%	0.789	S	S	*	*			trans	-160.1	143.4	151.1	-111.8	-79.2	0	0	0	114.4
453	H	44.7	Very low	42.9	Very low	153 Å²	153	176.9 Å²	176.9	71%	0.708	79%	0.792	S	S	*	*			trans	-42	150.1	-175.9	-79.8	-94.5	0	0	0	121.8
454	Q	46.2	Very low	42.5	Very low	188 Å²	188	176.1 Å²	176.1	88%	0.879	79%	0.793	S	S	*	*				-179.2	142	97.1	-95.8	-168.9	-9.6	0	0	113.5
455	P	42.1	Very low	42.2	Very low	97 Å²	97	175.2 Å²	175.2	63%	0.63	80%	0.799	S	S	*	*			trans	-112.3	-170.7	177.2	40.9	-30	0	0	0	114.2
456	Y	45.1	Very low	41.9	Very low	216 Å²	216	174.5 Å²	174.5	85%	0.847	80%	0.8	S	S	*	*			trans	94.6	128.9	-174.2	-60.5	-76.1	0	0	0	112.9
457	Q	44.1	Very low	41.5	Very low	178 Å²	178	175.8 Å²	175.8	83%	0.832	81%	0.806	S	S	*	*			cis	-163.8	161.6	33.3	-135.1	167.3	5.8	0	0	111.8
458	Q	42.3	Very low	41.4	Very low	182 Å²	182	175.1 Å²	175.1	85%	0.85	81%	0.805	S	S	*	*			trans	-67	150	-172.8	-66.8	146.9	-53.7	0	0	115.5
459	C	37.5	Very low	41.2	Very low	128 Å²	128	172.3 Å²	172.3	87%	0.865	80%	0.804	S	S	*	*				-164.8	114.5	115.9	-149.4	0	0	0	0	111.4
460	Q	38.8	Very low	40.9	Very low	190 Å²	190	169.7 Å²	169.7	89%	0.888	80%	0.796	S	S	*	*			trans	-76.5	120.2	172.3	-70.5	176.5	-16.4	0	0	110
461	R	40	Very low	40.9	Very low	219 Å²	219	164.4 Å²	164.4	83%	0.826	78%	0.78	S	S	*	*			trans	-135.2	106	150.1	-89	-170.7	178.4	172.8	0.1	109.3	F463	R461-F463 PolarHBondContact O-N 2.04Å; R461-F463 VanDerWaalsContact O-N 3.12Å
462	K	36.4	Very low	40.7	Very low	211 Å²	211	159.8 Å²	159.8	92%	0.917	76%	0.76	S	S	*	*			trans	-56.6	107.5	161.6	-75	176.9	174.5	177.8	0	108.2
463	F	40.2	Very low	40.3	Very low	186 Å²	186	151.7 Å²	151.7	82%	0.816	74%	0.736	S	S	*	*			trans	-108.2	113	160.3	-108.9	-89.2	0	0	0	106.9	R461	R461-F463 PolarHBondContact O-N 2.04Å; R461-F463 VanDerWaalsContact O-N 3.12Å
464	N	38.4	Very low	40.2	Very low	135 Å²	135	147.2 Å²	147.2	72%	0.722	72%	0.715	S	S	*	*			trans	-55.5	125.6	168.6	-70.2	-23.2	0	0	0	108.5	L466	N464-L466 PolarHBondContact O-N 2.79Å; N464-L466 VanDerWaalsContact O-N 3.11Å
465	P	42.3	Very low	39.7	Very low	127 Å²	127	146.6 Å²	146.6	83%	0.825	71%	0.706	S	S	*	*			trans	-71.2	109.7	165.8	28.4	-27.2	0	0	0	107.1	E467	P465-E467 PolarHBondContact O-N 3.11Å
466	L	40.7	Very low	39.5	Very low	130 Å²	130	144.6 Å²	144.6	68%	0.681	69%	0.694	S	S	*	*			trans	-48.2	120.3	165.8	-112.8	77.4	0	0	0	108.9	N464 Y468	N464-L466 PolarHBondContact O-N 2.79Å; N464-L466 VanDerWaalsContact O-N 3.11Å; L466-Y468 HydrophobicContact CB-CD2 3.75Å; L466-Y468 HydrophobicContact CB-CE2 4.44Å; L466-Y468 HydrophobicContact CD2-CD2 3.42Å; L466-Y468 VanDerWaalsContact CD2-CD2 3.42Å; L466-Y468 HydrophobicContact CD2-CE2 3.34Å; L466-Y468 HydrophobicContact CD2-CG 4.29Å; L466-Y468 HydrophobicContact CG-CD2 3.71Å; L466-Y468 HydrophobicContact CG-CE2 3.89Å; L466-Y468 PolarHBondContact O-N 3.49Å
467	E	36.2	Very low	39.2	Very low	173 Å²	173	140 Å²	140	81%	0.808	68%	0.681	S	S	*	*			trans	-66.4	71.8	171.4	-162.1	-179	178.4	0	0	109.6	P465	P465-E467 PolarHBondContact O-N 3.11Å
468	Y	38.8	Very low	38.9	Very low	200 Å²	200	140.2 Å²	140.2	78%	0.784	68%	0.679	S	S	*	*			trans	-122.3	62.7	-174.4	-96.1	-100.2	0	0	0	111.1	L466	L466-Y468 HydrophobicContact CB-CD2 3.75Å; L466-Y468 HydrophobicContact CB-CE2 4.44Å; L466-Y468 HydrophobicContact CD2-CD2 3.42Å; L466-Y468 VanDerWaalsContact CD2-CD2 3.42Å; L466-Y468 HydrophobicContact CD2-CE2 3.34Å; L466-Y468 HydrophobicContact CD2-CG 4.29Å; L466-Y468 HydrophobicContact CG-CD2 3.71Å; L466-Y468 HydrophobicContact CG-CE2 3.89Å; L466-Y468 PolarHBondContact O-N 3.49Å
469	S	38.3	Very low	38.9	Very low	107 Å²	107	136.2 Å²	136.2	75%	0.748	66%	0.66	S	S	*	*			trans	-150	37.5	169.9	63.7	0	0	0	0	113.4	Q471	S469-Q471 PolarHBondContact O-N 3.36Å
470	K	37.6	Very low	39.3	Very low	131 Å²	131	137 Å²	137	57%	0.57	66%	0.655	S	S	*	*			trans	-75.9	95.7	165.8	-78.9	-173.5	179.2	177.7	0	109.6
471	Q	42.4	Very low	39.8	Very low	110 Å²	110	134.1 Å²	134.1	51%	0.514	64%	0.641	S	S	.	*			trans	-46.8	146.6	166.2	-74.9	170.4	-32.1	0	0	110.7	S469 S473	S469-Q471 PolarHBondContact O-N 3.36Å; Q471-S473 PolarHBondContact O-N 3.48Å
472	L	38.4	Very low	40.2	Very low	70 Å²	70	129.4 Å²	129.4	37%	0.366	63%	0.632	S	S	.	*			trans	-62	77.1	162.7	-91.2	85.4	0	0	0	109.2	T229 S243 F474	T229-L472 HydrophobicContact CG2-CD1 3.83Å; T229-L472 HydrophobicContact CG2-CD2 4Å; S243-L472 PolarHBondContact OG-O 3.32Å; L472-F474 HydrophobicContact CD2-CD2 4.39Å; L472-F474 HydrophobicContact CD2-CE2 3.6Å; L472-F474 HydrophobicContact CD2-CZ 4.25Å; L472-F474 HydrophobicContact CG-CE2 4.15Å
473	S	35.1	Very low	40.8	Very low	55 Å²	55	125.4 Å²	125.4	39%	0.385	62%	0.615	S	S	.	*			trans	-98.7	91.9	161	51.9	0	0	0	0	106.2	Q471 Y475	Q471-S473 PolarHBondContact O-N 3.48Å; S473-Y475 PolarHBondContact O-N 3.27Å; S473-Y475 WeakPolarHBondContact OG-CD2 3.38Å; S473-Y475 VanDerWaalsContact OG-CE2 3.26Å; S473-Y475 WeakPolarHBondContact OG-CE2 3.22Å
474	F	42.5	Very low	41.3	Very low	59 Å²	59	122.8 Å²	122.8	26%	0.259	61%	0.605	S	S	.	*			trans	-73.9	83.7	164.6	-70.8	-69.7	0	0	0	107.2	S136 Q242 E246 L472 C476	S136-F474 VanDerWaalsContact O-CE1 3.27Å; S136-F474 WeakPolarHBondContact O-CE1 3.11Å; S136-F474 VanDerWaalsContact O-CZ 3.27Å; S136-F474 WeakPolarHBondContact O-CZ 3.35Å; Q242-F474 PolarHBondContact NE2-O 3.14Å; E246-F474 HydrophobicContact CB-CD2 4.01Å; E246-F474 HydrophobicContact CG-CB 3.94Å; E246-F474 HydrophobicContact CG-CD2 3.88Å; E246-F474 HydrophobicContact CG-CG 4.24Å; L472-F474 HydrophobicContact CD2-CD2 4.39Å; L472-F474 HydrophobicContact CD2-CE2 3.6Å; L472-F474 HydrophobicContact CD2-CZ 4.25Å; L472-F474 HydrophobicContact CG-CE2 4.15Å; F474-C476 VanDerWaalsContact C-N 3.33Å; F474-C476 PolarHBondContact O-N 3.03Å
475	Y	37.1	Very low	42	Very low	174 Å²	174	121.1 Å²	121.1	68%	0.682	60%	0.595	S	S	*	*			trans	-63.7	88.1	174.3	-86.2	-85.3	0	0	0	109.7	Q145 S473 M477	Q145-Y475 PolarHBondContact NE2-O 3.21Å; Q145-Y475 PolarHBondContact OE1-O 3.41Å; S473-Y475 PolarHBondContact O-N 3.27Å; S473-Y475 WeakPolarHBondContact OG-CD2 3.38Å; S473-Y475 VanDerWaalsContact OG-CE2 3.26Å; S473-Y475 WeakPolarHBondContact OG-CE2 3.22Å; Y475-M477 PolarHBondContact O-N 3.15Å
476	C	38.4	Very low	42.5	Very low	56 Å²	56	121.8 Å²	121.8	38%	0.378	59%	0.588	S	S	.	*			trans	-71.7	106.7	157.2	-128.6	0	0	0	0	105.9	F474 K478	F474-C476 VanDerWaalsContact C-N 3.33Å; F474-C476 PolarHBondContact O-N 3.03Å; C476-K478 PolarHBondContact O-N 3.47Å
477	M	38.6	Very low	43.3	Very low	120 Å²	120	121.4 Å²	121.4	59%	0.591	59%	0.586	S	S	*	*			trans	-50.2	125.1	-170.8	-117	-179	-176.6	0	0	112.7	Y475 E479	Y475-M477 PolarHBondContact O-N 3.15Å; M477-E479 HydrophobicContact CB-CB 3.98Å; M477-E479 VanDerWaalsContact CE-CD 3.46Å; M477-E479 HydrophobicContact CE-CG 4.39Å; M477-E479 WeakPolarHBondContact CE-OE1 3.26Å; M477-E479 HydrophobicContact CG-CB 3.91Å; M477-E479 HydrophobicContact CG-CG 4.44Å; M477-E479 PolarHBondContact O-N 3.49Å; M477-E479 VanDerWaalsContact O-N 3.16Å; M477-E479 HydrophobicContact SD-CB 3.8Å; M477-E479 HydrophobicContact SD-CG 4.02Å
478	K	37.6	Very low	44.3	Very low	182 Å²	182	120.7 Å²	120.7	79%	0.791	58%	0.583	S	S	*	*			trans	-82.2	44.5	167	-159.6	-174.9	-178.3	-169.9	0	110.3	C476 I480	C476-K478 PolarHBondContact O-N 3.47Å; K478-I480 PolarHBondContact O-N 3.38Å
479	E	41.1	Very low	45.2	Very low	97 Å²	97	119.3 Å²	119.3	45%	0.453	58%	0.584	S	S	.	*	T	Hydrogen-bonded Turn	trans	-95	24.8	-164.2	-142	-172	-147.1	0	0	115.2	M477 K483	M477-E479 HydrophobicContact CB-CB 3.98Å; M477-E479 VanDerWaalsContact CE-CD 3.46Å; M477-E479 HydrophobicContact CE-CG 4.39Å; M477-E479 WeakPolarHBondContact CE-OE1 3.26Å; M477-E479 HydrophobicContact CG-CB 3.91Å; M477-E479 HydrophobicContact CG-CG 4.44Å; M477-E479 PolarHBondContact O-N 3.49Å; M477-E479 VanDerWaalsContact O-N 3.16Å; M477-E479 HydrophobicContact SD-CB 3.8Å; M477-E479 HydrophobicContact SD-CG 4.02Å; E479-K483 IonicContact OE2-NZ 3.92Å
480	I	47.4	Very low	46.5	Very low	146 Å²	146	125 Å²	125	75%	0.749	60%	0.598	S	S	*	*	T	Hydrogen-bonded Turn	trans	-113.5	-14.1	173	-62.8	179	0	0	0	112.4	K478	K478-I480 PolarHBondContact O-N 3.38Å
481	H	47.8	Very low	46.9	Very low	128 Å²	128	124.8 Å²	124.8	59%	0.593	60%	0.6	S	S	*	*	S	Bend	trans	-89.6	-21.1	-178.4	-123.9	-47.7	0	0	0	115.2
482	D	49.5	Very low	47.2	Very low	120 Å²	120	125.5 Å²	125.5	64%	0.642	60%	0.604	S	S	*	*	H	α-helix	trans	-95.8	-17.9	-178.8	-67.5	-23.1	0	0	0	113.5
483	K	48.1	Very low	47.6	Very low	127 Å²	127	128.6 Å²	128.6	55%	0.552	62%	0.618	S	S	*	*	H	α-helix	trans	-80.6	-16.8	173.8	-78.1	178.8	177.9	163.8	0	113.9	E479	E479-K483 IonicContact OE2-NZ 3.92Å
484	H	51.3	Low	48.4	Very low	132 Å²	132	132.9 Å²	132.9	61%	0.611	63%	0.631	S	S	*	*	H	α-helix	trans	-85.6	-26	172.3	-109.6	-72.5	0	0	0	113
485	L	52.5	Low	48.7	Very low	99 Å²	99	137.6 Å²	137.6	52%	0.518	66%	0.655	S	S	.	*	H	α-helix	trans	-81.2	-21.2	176.1	-100.9	108.8	0	0	0	114.2
486	Q	53	Low	49.5	Very low	142 Å²	142	135.1 Å²	135.1	66%	0.664	65%	0.653	S	S	*	*	S	Bend	trans	-84.1	-17.2	174.8	-78.6	-173.6	-29.6	0	0	114
487	N	56.8	Low	50.3	Low	121 Å²	121	140.8 Å²	140.8	65%	0.647	67%	0.672	S	S	*	*	S	Bend	trans	-94.8	-0.2	174	-76.8	-1	0	0	0	113.6
488	E	57.8	Low	51.2	Low	159 Å²	159	142.4 Å²	142.4	74%	0.743	68%	0.679	S	S	*	*	S	Bend	trans	-104.9	4.3	168.4	-72.9	-173.7	157.9	0	0	112.5
489	Q	57.5	Low	52.3	Low	171 Å²	171	139.1 Å²	139.1	80%	0.799	67%	0.669	S	S	*	*			trans	-119	11.4	175.1	-72	-169	-24.9	0	0	114
490	Q	65.3	Low	53.4	Low	227 Å²	227	142.9 Å²	142.9	100%	1.061	69%	0.689	S	S	*	*			trans	-118.2	0	162	-79.3	-174.1	-25.5	0	0	108.3

Retrieved 490 of 490 residues in 314.1 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).