A0A3Q0KL75_SCHMA Loading...

G_PROTEIN_RECEP_F1_2 domain-containing protein

AlphaFold DB , UniProt , Accession A0A3Q0KL75, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 520 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	35.5	Very low	30	Very low	251 Å²	251	149.5 Å²	149.5	100%	1.236	84%	0.844	S	S	*	*				0	111.8	0	-69.5	175.3	175.7	0	0	107
2	A	34.8	Very low	30	Very low	93 Å²	93	150.5 Å²	150.5	77%	0.769	84%	0.843	S	S	*	*			cis	-133.2	117.8	-2.1	0	0	0	0	0	107.8
3	V	31.7	Very low	29.7	Very low	139 Å²	139	143.5 Å²	143.5	84%	0.842	83%	0.826	S	S	*	*				88.9	118.2	99.7	177.6	0	0	0	0	112.7
4	E	30.2	Very low	29.8	Very low	178 Å²	178	144.1 Å²	144.1	83%	0.832	81%	0.814	S	S	*	*			trans	-45	151.2	167.7	-66.7	162.9	128.5	0	0	114
5	K	32.9	Very low	30	Very low	191 Å²	191	139.5 Å²	139.5	83%	0.83	79%	0.793	S	S	*	*				-157	106.3	129.8	-111.2	176.1	-175.3	-173.1	0	110.6
6	S	28.4	Very low	30.2	Very low	109 Å²	109	144.3 Å²	144.3	76%	0.762	79%	0.794	S	S	*	*			trans	-68.4	121.6	155.2	54.8	0	0	0	0	108.4
7	D	31.5	Very low	30.7	Very low	132 Å²	132	139.9 Å²	139.9	71%	0.706	78%	0.776	S	S	*	*			trans	-132.5	112.6	157.6	-90.7	-36.8	0	0	0	109.6	S9	D7-S9 PolarHBondContact O-N 3.07Å
8	S	26.4	Very low	31.1	Very low	120 Å²	120	135.2 Å²	135.2	84%	0.839	75%	0.751	S	S	*	*			trans	-60.3	96	166.7	47.2	0	0	0	0	111.1
9	S	25.8	Very low	31.4	Very low	107 Å²	107	130.2 Å²	130.2	75%	0.748	73%	0.727	S	S	*	*			trans	-172.1	88.6	160.3	57.9	0	0	0	0	111.4	D7	D7-S9 PolarHBondContact O-N 3.07Å
10	S	27	Very low	31.9	Very low	116 Å²	116	130 Å²	130	81%	0.811	72%	0.72	S	S	*	*			trans	-146.1	83.4	161.6	52.1	0	0	0	0	110.4
11	F	26	Very low	32.3	Very low	208 Å²	208	130.1 Å²	130.1	91%	0.912	71%	0.713	S	S	*	*			trans	-33.8	136.9	141.1	-133.4	-102.6	0	0	0	108.9	G13	F11-G13 PolarHBondContact O-N 3.49Å
12	I	29.2	Very low	32.4	Very low	162 Å²	162	120.3 Å²	120.3	83%	0.831	67%	0.665	S	S	*	*	S	Bend	trans	-54.9	89.6	176.2	-61.3	167.9	0	0	0	108
13	G	26.2	Very low	32.7	Very low	60 Å²	60	124 Å²	124	62%	0.619	66%	0.661	S	S	*	*			trans	-106	113.1	178.6	0	0	0	0	0	106.1	F11	F11-G13 PolarHBondContact O-N 3.49Å
14	F	32	Very low	33.1	Very low	151 Å²	151	122.6 Å²	122.6	66%	0.662	65%	0.648	S	S	*	*			trans	-54.3	131.7	169.5	-75.6	-88.9	0	0	0	108.2	R16 V18	F14-R16 PolarHBondContact O-N 3.49Å; F14-V18 HydrophobicContact CD1-CG1 4.18Å
15	P	32.3	Very low	33.6	Very low	76 Å²	76	114.7 Å²	114.7	49%	0.494	61%	0.613	S	S	.	*			trans	-54.2	135.3	176	21.3	-30.5	0	0	0	108.6	S17 V18 S19	P15-S17 PolarHBondContact O-N 3.45Å; P15-V18 HydrophobicContact CG-CB 4.2Å; P15-V18 HydrophobicContact CG-CG2 3.73Å; P15-V18 PolarHBondContact O-N 3.48Å; P15-S19 PolarHBondContact O-N 3.02Å
16	R	33	Very low	33.9	Very low	216 Å²	216	108.3 Å²	108.3	82%	0.815	59%	0.587	S	S	*	*	H	α-helix	trans	-48.2	-28.9	-177.5	-95.5	-178.4	172.9	172.4	-3.1	113.5	F14 V18 S19 E20	F14-R16 PolarHBondContact O-N 3.49Å; R16-V18 PolarHBondContact O-N 3.16Å; R16-S19 WeakPolarHBondContact CA-OG 3.47Å; R16-S19 PolarHBondContact O-N 3.01Å; R16-S19 PolarHBondContact O-OG 3.4Å; R16-E20 PolarHBondContact O-N 2.98Å
17	S	39.6	Very low	34.4	Very low	70 Å²	70	106.5 Å²	106.5	49%	0.49	57%	0.569	S	S	.	*	H	α-helix	trans	-67.9	-28.5	176	58.7	0	0	0	0	114.6	P15 K21	P15-S17 PolarHBondContact O-N 3.45Å; S17-K21 WeakPolarHBondContact O-CG 3.34Å; S17-K21 PolarHBondContact O-N 3.07Å
18	V	38	Very low	34.8	Very low	54 Å²	54	103.9 Å²	103.9	33%	0.327	55%	0.55	S	S	.	.	H	α-helix	trans	-81.8	-37.6	175.7	174.1	0	0	0	0	110	F14 P15 R16 K21 I22	F14-V18 HydrophobicContact CD1-CG1 4.18Å; P15-V18 HydrophobicContact CG-CB 4.2Å; P15-V18 HydrophobicContact CG-CG2 3.73Å; P15-V18 PolarHBondContact O-N 3.48Å; R16-V18 PolarHBondContact O-N 3.16Å; V18-K21 PolarHBondContact O-N 3.43Å; V18-I22 HydrophobicContact CG1-CD1 3.71Å; V18-I22 HydrophobicContact CG1-CG1 4.38Å; V18-I22 WeakPolarHBondContact O-CB 3.44Å; V18-I22 VanDerWaalsContact O-CD1 3.3Å; V18-I22 WeakPolarHBondContact O-CD1 3.44Å; V18-I22 WeakPolarHBondContact O-CG1 3.5Å; V18-I22 PolarHBondContact O-N 3.17Å
19	S	36.7	Very low	35.5	Very low	40 Å²	40	101.6 Å²	101.6	28%	0.28	53%	0.525	S	S	.	.	H	α-helix	trans	-66	-40.3	173.6	53.9	0	0	0	0	112.7	P15 R16 I22 Y23	P15-S19 PolarHBondContact O-N 3.02Å; R16-S19 WeakPolarHBondContact CA-OG 3.47Å; R16-S19 PolarHBondContact O-N 3.01Å; R16-S19 PolarHBondContact O-OG 3.4Å; S19-I22 CarbonylContact O-C 3.58Å; S19-I22 WeakPolarHBondContact O-CA 3.37Å; S19-I22 WeakPolarHBondContact O-CB 3.31Å; S19-I22 PolarHBondContact O-N 3.18Å; S19-I22 VanDerWaalsContact O-N 3.14Å; S19-Y23 VanDerWaalsContact O-CD2 3.26Å; S19-Y23 WeakPolarHBondContact O-CD2 3.25Å; S19-Y23 PolarHBondContact O-N 3.34Å
20	E	40.8	Very low	36.1	Very low	127 Å²	127	102.6 Å²	102.6	59%	0.593	52%	0.518	S	S	*	.	H	α-helix	trans	-63	-47.1	174.4	-84.1	174.4	165.2	0	0	111.5	R16 I22 Y23 D24	R16-E20 PolarHBondContact O-N 2.98Å; E20-I22 PolarHBondContact O-N 3.47Å; E20-Y23 PolarHBondContact O-N 3.33Å; E20-Y23 VanDerWaalsContact O-N 3.12Å; E20-D24 WeakPolarHBondContact O-CB 3.49Å; E20-D24 PolarHBondContact O-N 3.48Å
21	K	40.1	Very low	36.5	Very low	132 Å²	132	105 Å²	105	57%	0.574	51%	0.51	S	S	*	.	H	α-helix	trans	-58.5	-32.5	172.1	-76.1	-175.1	176.8	-165.7	0	112.6	S17 V18 C25	S17-K21 WeakPolarHBondContact O-CG 3.34Å; S17-K21 PolarHBondContact O-N 3.07Å; V18-K21 PolarHBondContact O-N 3.43Å; K21-C25 WeakPolarHBondContact O-CB 3.47Å; K21-C25 PolarHBondContact O-N 2.93Å; K21-C25 VanDerWaalsContact O-N 3.09Å; K21-C25 PolarHBondContact O-SG 3.31Å
22	I	37.9	Very low	36.9	Very low	46 Å²	46	101 Å²	101	24%	0.236	50%	0.504	C	S	.	.	H	α-helix	trans	-68.8	-46.3	174.1	-68.8	160.7	0	0	0	112.8	V18 S19 E20 C25 L26 I83	V18-I22 HydrophobicContact CG1-CD1 3.71Å; V18-I22 HydrophobicContact CG1-CG1 4.38Å; V18-I22 WeakPolarHBondContact O-CB 3.44Å; V18-I22 VanDerWaalsContact O-CD1 3.3Å; V18-I22 WeakPolarHBondContact O-CD1 3.44Å; V18-I22 WeakPolarHBondContact O-CG1 3.5Å; V18-I22 PolarHBondContact O-N 3.17Å; S19-I22 CarbonylContact O-C 3.58Å; S19-I22 WeakPolarHBondContact O-CA 3.37Å; S19-I22 WeakPolarHBondContact O-CB 3.31Å; S19-I22 PolarHBondContact O-N 3.18Å; S19-I22 VanDerWaalsContact O-N 3.14Å; E20-I22 PolarHBondContact O-N 3.47Å; I22-C25 PolarHBondContact O-N 3.44Å; I22-L26 HydrophobicContact CG2-CD1 3.68Å; I22-L26 WeakPolarHBondContact O-CB 3.43Å; I22-L26 WeakPolarHBondContact O-CG 3.43Å; I22-L26 PolarHBondContact O-N 3.06Å; I22-I83 HydrophobicContact CB-CD1 3.78Å; I22-I83 HydrophobicContact CB-CG1 4.48Å; I22-I83 HydrophobicContact CG1-CD1 3.39Å; I22-I83 HydrophobicContact CG1-CG1 3.63Å; I22-I83 HydrophobicContact CG2-CD1 4.14Å
23	Y	40.2	Very low	37.4	Very low	171 Å²	171	98.2 Å²	98.2	67%	0.671	49%	0.49	S	S	*	.	H	α-helix	trans	-63.9	-41.7	175.8	-88.8	-75.7	0	0	0	111.7	S19 E20 L26 D27	S19-Y23 VanDerWaalsContact O-CD2 3.26Å; S19-Y23 WeakPolarHBondContact O-CD2 3.25Å; S19-Y23 PolarHBondContact O-N 3.34Å; E20-Y23 PolarHBondContact O-N 3.33Å; E20-Y23 VanDerWaalsContact O-N 3.12Å; Y23-L26 PolarHBondContact O-N 3.15Å; Y23-D27 WeakPolarHBondContact O-CB 3.44Å; Y23-D27 PolarHBondContact O-N 2.94Å
24	D	40.6	Very low	37.5	Very low	109 Å²	109	104.9 Å²	104.9	58%	0.583	50%	0.502	S	S	*	.	H	α-helix	trans	-65.6	-41.8	178.4	-70.7	-22.5	0	0	0	111.9	E20 Y28	E20-D24 WeakPolarHBondContact O-CB 3.49Å; E20-D24 PolarHBondContact O-N 3.48Å; D24-Y28 WeakPolarHBondContact O-CB 3.37Å; D24-Y28 PolarHBondContact O-N 2.94Å
25	C	41.9	Very low	37.7	Very low	12 Å²	12	101.7 Å²	101.7	8%	0.081	49%	0.49	C	S	.	.	H	α-helix	trans	-67.4	-35.4	173.9	-70.2	0	0	0	0	112.6	K21 I22 H29 C81 I83	K21-C25 WeakPolarHBondContact O-CB 3.47Å; K21-C25 PolarHBondContact O-N 2.93Å; K21-C25 VanDerWaalsContact O-N 3.09Å; K21-C25 PolarHBondContact O-SG 3.31Å; I22-C25 PolarHBondContact O-N 3.44Å; C25-H29 PolarHBondContact O-CD2 3.1Å; C25-H29 VanDerWaalsContact O-CD2 3.25Å; C25-H29 PolarHBondContact O-N 2.92Å; C25-C81 HydrophobicContact CB-CB 4.08Å; C25-C81 WeakPolarHBondContact CB-SG 3.35Å; C25-C81 VanDerWaalsContact SG-CA 3.55Å; C25-C81 WeakPolarHBondContact SG-CB 3.41Å; C25-C81 CovalentContact SG-SG 2.03Å; C25-C81 PolarHBondContact SG-SG 2.92Å; C25-I83 HydrophobicContact CB-CD1 3.64Å
26	L	37.8	Very low	37.4	Very low	56 Å²	56	105.2 Å²	105.2	29%	0.293	51%	0.505	S	S	.	.	H	α-helix	trans	-70.4	-44.3	176.2	-84.4	161.5	0	0	0	112	I22 Y23 Y28 H29 Q30 I444	I22-L26 HydrophobicContact CG2-CD1 3.68Å; I22-L26 WeakPolarHBondContact O-CB 3.43Å; I22-L26 WeakPolarHBondContact O-CG 3.43Å; I22-L26 PolarHBondContact O-N 3.06Å; Y23-L26 PolarHBondContact O-N 3.15Å; L26-Y28 VanDerWaalsContact C-N 3.32Å; L26-Y28 PolarHBondContact O-N 3.41Å; L26-H29 PolarHBondContact O-N 3.4Å; L26-Q30 WeakPolarHBondContact O-CB 3.5Å; L26-Q30 WeakPolarHBondContact O-CG 3.43Å; L26-Q30 PolarHBondContact O-N 3.32Å; L26-I444 HydrophobicContact CD2-CD1 4.16Å
27	D	38.9	Very low	37.3	Very low	71 Å²	71	103.4 Å²	103.4	38%	0.38	50%	0.503	S	S	.	.	H	α-helix	trans	-65.8	-37.7	177.9	-160.5	47.3	0	0	0	110.6	Y23 H29 Q30 R31	Y23-D27 WeakPolarHBondContact O-CB 3.44Å; Y23-D27 PolarHBondContact O-N 2.94Å; D27-H29 VanDerWaalsContact C-N 3.32Å; D27-H29 PolarHBondContact O-N 3.36Å; D27-Q30 PolarHBondContact O-N 3Å; D27-R31 WeakPolarHBondContact O-CG 3.48Å; D27-R31 PolarHBondContact O-N 3.45Å; D27-R31 IonicContact OD2-CZ 2.79Å; D27-R31 IonicContact OD2-NE 2.69Å; D27-R31 PolarHBondContact OD2-NE 3.1Å; D27-R31 IonicContact OD2-NH2 3.39Å; D27-R31 PolarHBondContact OD2-NH2 3.49Å
28	Y	39.3	Very low	36.8	Very low	78 Å²	78	106.1 Å²	106.1	31%	0.306	52%	0.517	S	S	.	.	H	α-helix	trans	-61.7	-36.6	173.7	-173.8	-96.1	0	0	0	113.2	D24 L26 P76	D24-Y28 WeakPolarHBondContact O-CB 3.37Å; D24-Y28 PolarHBondContact O-N 2.94Å; L26-Y28 VanDerWaalsContact C-N 3.32Å; L26-Y28 PolarHBondContact O-N 3.41Å; Y28-P76 WeakPolarHBondContact CE1-O 3.49Å; Y28-P76 WeakPolarHBondContact OH-CB 3.12Å; Y28-P76 WeakPolarHBondContact OH-CD 3.4Å; Y28-P76 WeakPolarHBondContact OH-CG 3.47Å; Y28-P76 PolarHBondContact OH-O 2.74Å
29	H	42	Very low	36.3	Very low	71 Å²	71	111.5 Å²	111.5	33%	0.329	54%	0.536	S	S	.	.	H	α-helix	trans	-81.7	-21.1	176.2	-83.2	-65.2	0	0	0	114.2	C25 L26 D27 R75	C25-H29 PolarHBondContact O-CD2 3.1Å; C25-H29 VanDerWaalsContact O-CD2 3.25Å; C25-H29 PolarHBondContact O-N 2.92Å; L26-H29 PolarHBondContact O-N 3.4Å; D27-H29 VanDerWaalsContact C-N 3.32Å; D27-H29 PolarHBondContact O-N 3.36Å; H29-R75 PolarHBondContact ND1-NH2 3.41Å; H29-R75 VanDerWaalsContact ND1-NH2 3.12Å
30	Q	38.4	Very low	36.1	Very low	128 Å²	128	116.6 Å²	116.6	60%	0.598	56%	0.559	S	S	*	*	H	α-helix	trans	-93.5	-16.2	-178.7	-78.6	-175.3	-16.3	0	0	114.8	L26 D27 P32	L26-Q30 WeakPolarHBondContact O-CB 3.5Å; L26-Q30 WeakPolarHBondContact O-CG 3.43Å; L26-Q30 PolarHBondContact O-N 3.32Å; D27-Q30 PolarHBondContact O-N 3Å; Q30-P32 VanDerWaalsContact O-CD 3.23Å; Q30-P32 WeakPolarHBondContact O-CD 3.47Å
31	R	35.1	Very low	35.4	Very low	167 Å²	167	117 Å²	117	63%	0.63	56%	0.562	S	S	*	*	S	Bend	trans	-66	119.8	175.8	-79.1	179.8	-167.4	-168	6	110.8	D27 I33	D27-R31 WeakPolarHBondContact O-CG 3.48Å; D27-R31 PolarHBondContact O-N 3.45Å; D27-R31 IonicContact OD2-CZ 2.79Å; D27-R31 IonicContact OD2-NE 2.69Å; D27-R31 PolarHBondContact OD2-NE 3.1Å; D27-R31 IonicContact OD2-NH2 3.39Å; D27-R31 PolarHBondContact OD2-NH2 3.49Å; R31-I33 VanDerWaalsContact C-N 3.29Å; R31-I33 PolarHBondContact O-N 3.43Å
32	P	34	Very low	34.9	Very low	123 Å²	123	117.8 Å²	117.8	80%	0.799	57%	0.572	S	S	*	*			trans	-68.6	95	164.9	28.7	-29.8	0	0	0	106.7	Q30 K34	Q30-P32 VanDerWaalsContact O-CD 3.23Å; Q30-P32 WeakPolarHBondContact O-CD 3.47Å; P32-K34 PolarHBondContact O-N 2.91Å
33	I	39.5	Very low	34.6	Very low	104 Å²	104	122.8 Å²	122.8	53%	0.533	60%	0.597	S	S	.	*			trans	-65.3	110	171.5	-60.3	175.8	0	0	0	105.6	R31 M35	R31-I33 VanDerWaalsContact C-N 3.29Å; R31-I33 PolarHBondContact O-N 3.43Å; I33-M35 HydrophobicContact CG2-CG 3.92Å; I33-M35 PolarHBondContact O-N 3.03Å
34	K	29.3	Very low	34	Very low	200 Å²	200	120.1 Å²	120.1	87%	0.87	60%	0.599	S	S	*	*			trans	-58.3	86.6	159.7	-76.5	-178.9	176	179.9	0	106.7	P32 N36	P32-K34 PolarHBondContact O-N 2.91Å; K34-N36 PolarHBondContact O-N 2.87Å
35	M	35.6	Very low	33.3	Very low	85 Å²	85	125.8 Å²	125.8	42%	0.419	61%	0.614	S	S	.	*			trans	-68.9	105.7	170.7	-74.9	-172.2	174	0	0	106.7	I33 F37 S74	I33-M35 HydrophobicContact CG2-CG 3.92Å; I33-M35 PolarHBondContact O-N 3.03Å; M35-F37 WeakPolarHBondContact O-CD2 3.31Å; M35-F37 PolarHBondContact O-N 3.26Å; M35-F37 VanDerWaalsContact O-N 3.1Å; M35-S74 WeakPolarHBondContact CE-O 3.43Å
36	N	27.3	Very low	32.7	Very low	149 Å²	149	135.6 Å²	135.6	80%	0.797	65%	0.651	S	S	*	*			trans	-63.8	107.2	162.5	-96.6	-10.6	0	0	0	106.6	K34 T38	K34-N36 PolarHBondContact O-N 2.87Å; N36-T38 VanDerWaalsContact C-N 3.32Å; N36-T38 PolarHBondContact O-N 2.89Å
37	F	30	Very low	32.2	Very low	179 Å²	179	139.5 Å²	139.5	79%	0.785	67%	0.672	S	S	*	*			trans	-66.2	89.6	172.7	-64	-87.1	0	0	0	109.3	M35 K39	M35-F37 WeakPolarHBondContact O-CD2 3.31Å; M35-F37 PolarHBondContact O-N 3.26Å; M35-F37 VanDerWaalsContact O-N 3.1Å; F37-K39 PolarHBondContact O-N 3.49Å
38	T	29.3	Very low	31.6	Very low	127 Å²	127	145.4 Å²	145.4	78%	0.779	70%	0.7	S	S	*	*			trans	-80.8	100.5	163.6	43.8	0	0	0	0	108.1	N36 L40	N36-T38 VanDerWaalsContact C-N 3.32Å; N36-T38 PolarHBondContact O-N 2.89Å; T38-L40 PolarHBondContact O-N 3.43Å; T38-L40 VanDerWaalsContact O-N 3.14Å
39	K	27	Very low	31	Very low	167 Å²	167	146.9 Å²	146.9	73%	0.726	72%	0.717	S	S	*	*			trans	-48.1	113.7	168.5	-163.8	-175.8	179.2	-153.2	0	108.9	F37 E41	F37-K39 PolarHBondContact O-N 3.49Å; K39-E41 HydrophobicContact CD-CG 4.21Å; K39-E41 HydrophobicContact CG-CG 4.3Å; K39-E41 IonicContact NZ-OE1 2.82Å; K39-E41 PolarHBondContact NZ-OE1 3.22Å; K39-E41 PolarHBondContact O-N 3.02Å
40	L	32.2	Very low	30.3	Very low	146 Å²	146	151.6 Å²	151.6	76%	0.764	74%	0.744	S	S	*	*			trans	-74.8	77.8	175.3	-158.2	84.2	0	0	0	108.6	T38 N42	T38-L40 PolarHBondContact O-N 3.43Å; T38-L40 VanDerWaalsContact O-N 3.14Å; L40-N42 VanDerWaalsContact C-N 3.32Å; L40-N42 PolarHBondContact O-N 3.47Å
41	E	28	Very low	29.7	Very low	137 Å²	137	151 Å²	151	64%	0.64	75%	0.754	S	S	*	*			trans	-72.4	87.9	165.3	-77.4	179.5	174.8	0	0	108.1	K39	K39-E41 HydrophobicContact CD-CG 4.21Å; K39-E41 HydrophobicContact CG-CG 4.3Å; K39-E41 IonicContact NZ-OE1 2.82Å; K39-E41 PolarHBondContact NZ-OE1 3.22Å; K39-E41 PolarHBondContact O-N 3.02Å
42	N	29.4	Very low	29.4	Very low	147 Å²	147	149.5 Å²	149.5	79%	0.786	76%	0.757	S	S	*	*			trans	169.6	75	152.6	-87.7	-23.1	0	0	0	111	L40	L40-N42 VanDerWaalsContact C-N 3.32Å; L40-N42 PolarHBondContact O-N 3.47Å
43	I	30.6	Very low	29.3	Very low	151 Å²	151	152 Å²	152	77%	0.774	76%	0.758	S	S	*	*			trans	-129	98.2	151	-58.4	-179	0	0	0	107.4
44	T	28.5	Very low	29	Very low	115 Å²	115	151.6 Å²	151.6	71%	0.706	75%	0.754	S	S	*	*			trans	-49.2	125.5	170.4	34.6	0	0	0	0	112.7	Y46	T44-Y46 PolarHBondContact O-N 3.03Å
45	Y	25.5	Very low	29.4	Very low	228 Å²	228	147 Å²	147	89%	0.894	74%	0.739	S	S	*	*			trans	26.2	91.2	136.7	-90.8	-96.4	0	0	0	116.4
46	Y	27.9	Very low	29.3	Very low	219 Å²	219	150 Å²	150	86%	0.859	75%	0.745	S	S	*	*			trans	-147.7	110.8	150	-100.7	-79.7	0	0	0	110.9	T44	T44-Y46 PolarHBondContact O-N 3.03Å
47	N	28.2	Very low	29.7	Very low	137 Å²	137	145.8 Å²	145.8	73%	0.733	73%	0.725	S	S	*	*			trans	43.8	96	156.6	-74.9	-14.6	0	0	0	119.1	T49	N47-T49 PolarHBondContact O-N 2.86Å
48	M	26.2	Very low	29.8	Very low	196 Å²	196	141.7 Å²	141.7	97%	0.966	71%	0.71	S	S	*	*			trans	-54.5	96.3	142.7	-89.1	179.1	159.9	0	0	110.1
49	T	27.4	Very low	30.1	Very low	108 Å²	108	138.1 Å²	138.1	66%	0.663	69%	0.685	S	S	*	*	S	Bend	trans	-163.2	114.6	152.1	30	0	0	0	0	109.2	N47	N47-T49 PolarHBondContact O-N 2.86Å
50	N	26.3	Very low	30.7	Very low	170 Å²	170	136.5 Å²	136.5	91%	0.909	68%	0.68	S	S	*	*			trans	48.8	72.4	161.8	-62.2	-11.8	0	0	0	116.8
51	S	26	Very low	30.9	Very low	116 Å²	116	135.1 Å²	135.1	81%	0.811	68%	0.682	S	S	*	*			trans	-109.4	116.3	163.5	58.5	0	0	0	0	110.9	H53	S51-H53 PolarHBondContact O-N 3.28Å
52	I	28.9	Very low	31.4	Very low	135 Å²	135	133 Å²	133	69%	0.692	68%	0.675	S	S	*	*			trans	-49.4	127.1	163	-66.7	161.2	0	0	0	107.4	E54	I52-E54 HydrophobicContact CG2-CG 4.47Å; I52-E54 PolarHBondContact O-N 3.16Å
53	H	32.9	Very low	31.7	Very low	177 Å²	177	128 Å²	128	82%	0.819	65%	0.65	S	S	*	*			trans	-55.2	95.7	173	-82.8	-57.9	0	0	0	110.2	S51	S51-H53 PolarHBondContact O-N 3.28Å
54	E	33.6	Very low	32.1	Very low	95 Å²	95	121.8 Å²	121.8	44%	0.444	62%	0.618	S	S	.	*			trans	-102.3	106.8	172	-79.8	-174.2	168.6	0	0	109.2	I52 R56 R162	I52-E54 HydrophobicContact CG2-CG 4.47Å; I52-E54 PolarHBondContact O-N 3.16Å; E54-R56 PolarHBondContact O-N 3.43Å; E54-R162 IonicContact OE1-CZ 3.23Å; E54-R162 IonicContact OE1-NH1 2.89Å; E54-R162 PolarHBondContact OE1-NH1 3.26Å; E54-R162 IonicContact OE1-NH2 3.36Å; E54-R162 PolarHBondContact OE1-NH2 3.06Å
55	D	37.6	Very low	32.3	Very low	102 Å²	102	119.8 Å²	119.8	55%	0.545	60%	0.601	S	S	.	*			trans	-57.9	118.9	163.9	-66.5	-33.1	0	0	0	108.4	Y68	D55-Y68 WeakPolarHBondContact OD1-CD2 3.44Å
56	R	33.6	Very low	32.9	Very low	149 Å²	149	110 Å²	110	56%	0.562	56%	0.564	S	S	*	*	E	Extended strand (participates in β ladder)	trans	-107.4	123.9	174.8	-72.9	-171.4	-177	-171.4	1.8	109.7	E54 T67	E54-R56 PolarHBondContact O-N 3.43Å; R56-T67 PolarHBondContact O-N 2.86Å; R56-T67 VanDerWaalsContact O-N 3.11Å
57	V	34.1	Very low	33.1	Very low	61 Å²	61	102.1 Å²	102.1	37%	0.37	54%	0.539	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-103.9	119.1	166.8	-179.8	0	0	0	0	107.2	I59 I64 E65 I66	V57-I59 HydrophobicContact CG1-CG1 4.36Å; V57-I64 HydrophobicContact CG1-CG2 3.84Å; V57-E65 WeakPolarHBondContact CA-O 3.33Å; V57-I66 HydrophobicContact CG2-CG2 4.48Å
58	M	32.9	Very low	33.2	Very low	93 Å²	93	99.1 Å²	99.1	46%	0.458	52%	0.518	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-113.2	116.8	170.9	-73.8	-162.5	-119.1	0	0	109	E65	M58-E65 HydrophobicContact CB-CB 4.48Å; M58-E65 PolarHBondContact N-O 3.05Å; M58-E65 PolarHBondContact O-N 2.75Å
59	I	36.3	Very low	33.5	Very low	51 Å²	51	96 Å²	96	26%	0.262	50%	0.504	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-92.2	119.8	169.9	-52.3	171.7	0	0	0	108.1	V57 T63 I64 N154 I157	V57-I59 HydrophobicContact CG1-CG1 4.36Å; I59-T63 CarbonylContact C-O 3.28Å; I59-T63 WeakPolarHBondContact CA-O 2.99Å; I59-I64 HydrophobicContact CG1-CG1 4.46Å; I59-N154 WeakPolarHBondContact CB-OD1 3.22Å; I59-N154 WeakPolarHBondContact CD1-OD1 3.4Å; I59-N154 WeakPolarHBondContact CG1-OD1 3.48Å; I59-N154 PolarHBondContact N-ND2 3.49Å; I59-N154 PolarHBondContact N-OD1 3.35Å; I59-N154 PolarHBondContact O-ND2 3.2Å; I59-I157 HydrophobicContact CD1-CD1 4.31Å
60	H	38.1	Very low	33.8	Very low	134 Å²	134	98.8 Å²	98.8	62%	0.62	52%	0.515	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-114.3	100.2	173.1	-109.3	15.7	0	0	0	109.2	D62 T63	H60-D62 CarbonylContact O-C 3.57Å; H60-D62 PolarHBondContact O-N 3.44Å; H60-T63 PolarHBondContact N-O 3.4Å; H60-T63 PolarHBondContact O-N 3.26Å; H60-T63 PolarHBondContact O-OG1 3.4Å; H60-T63 VanDerWaalsContact O-OG1 3.11Å
61	S	37.2	Very low	34.1	Very low	116 Å²	116	95.4 Å²	95.4	81%	0.811	49%	0.494	S	S	*	.	T	Hydrogen-bonded Turn	trans	47.4	-47.6	169.9	-47.4	0	0	0	0	117.9
62	D	38.5	Very low	34.4	Very low	93 Å²	93	94.1 Å²	94.1	50%	0.497	48%	0.481	S	S	.	.	T	Hydrogen-bonded Turn	trans	-138.8	8.4	175.5	-62.3	-51.4	0	0	0	113.8	H60 P76 I77	H60-D62 CarbonylContact O-C 3.57Å; H60-D62 PolarHBondContact O-N 3.44Å; D62-P76 CarbonylContact O-C 3.58Å; D62-P76 VanDerWaalsContact O-C 3.28Å; D62-P76 WeakPolarHBondContact O-CA 3.33Å; D62-I77 PolarHBondContact O-N 2.87Å
63	T	34.7	Very low	34.8	Very low	41 Å²	41	91.8 Å²	91.8	25%	0.252	46%	0.464	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-133.1	137.8	179.3	52.8	0	0	0	0	112.7	I59 H60 R75 P76	I59-T63 CarbonylContact C-O 3.28Å; I59-T63 WeakPolarHBondContact CA-O 2.99Å; H60-T63 PolarHBondContact N-O 3.4Å; H60-T63 PolarHBondContact O-N 3.26Å; H60-T63 PolarHBondContact O-OG1 3.4Å; H60-T63 VanDerWaalsContact O-OG1 3.11Å; T63-R75 CarbonylContact C-O 3.57Å; T63-R75 WeakPolarHBondContact CA-O 3.19Å; T63-P76 HydrophobicContact CG2-CB 3.91Å; T63-P76 HydrophobicContact CG2-CG 4.39Å
64	I	39.4	Very low	35	Very low	22 Å²	22	86 Å²	86	11%	0.113	44%	0.444	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-93.3	118.9	162.5	-54.1	175.3	0	0	0	107.1	V57 I59 I66 S74 R75 I77 I357	V57-I64 HydrophobicContact CG1-CG2 3.84Å; I59-I64 HydrophobicContact CG1-CG1 4.46Å; I64-I66 HydrophobicContact CG2-CD1 3.91Å; I64-I66 HydrophobicContact CG2-CG1 3.5Å; I64-I66 VanDerWaalsContact CG2-CG1 3.5Å; I64-S74 CarbonylContact O-C 3.54Å; I64-S74 WeakPolarHBondContact O-CA 3.22Å; I64-R75 PolarHBondContact N-O 2.85Å; I64-R75 PolarHBondContact O-N 3.46Å; I64-I77 HydrophobicContact CD1-CD1 3.4Å; I64-I77 VanDerWaalsContact CD1-CD1 3.4Å; I64-I77 HydrophobicContact CD1-CG1 3.72Å; I64-I77 HydrophobicContact CG1-CD1 3.28Å; I64-I77 HydrophobicContact CG1-CG1 3.48Å; I64-I77 VanDerWaalsContact CG1-CG1 3.48Å; I64-I357 HydrophobicContact CD1-CD1 4.03Å
65	E	33.5	Very low	35.3	Very low	73 Å²	73	85 Å²	85	34%	0.341	44%	0.436	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.8	126.6	161.8	-72.2	-173.5	170.3	0	0	110	V57 M58 Y73	V57-E65 WeakPolarHBondContact CA-O 3.33Å; M58-E65 HydrophobicContact CB-CB 4.48Å; M58-E65 PolarHBondContact N-O 3.05Å; M58-E65 PolarHBondContact O-N 2.75Å; E65-Y73 CarbonylContact C-O 3.57Å; E65-Y73 VanDerWaalsContact CA-O 3.26Å; E65-Y73 WeakPolarHBondContact CA-O 3.41Å
66	I	38.3	Very low	35.2	Very low	22 Å²	22	82.5 Å²	82.5	11%	0.113	43%	0.425	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.3	115.6	177.1	-49.8	-178.8	0	0	0	107.4	V57 I64 T72 Y73 W351 P353	V57-I66 HydrophobicContact CG2-CG2 4.48Å; I64-I66 HydrophobicContact CG2-CD1 3.91Å; I64-I66 HydrophobicContact CG2-CG1 3.5Å; I64-I66 VanDerWaalsContact CG2-CG1 3.5Å; I66-T72 WeakPolarHBondContact O-CA 3.26Å; I66-Y73 PolarHBondContact N-O 2.9Å; I66-Y73 PolarHBondContact O-N 3.5Å; I66-W351 HydrophobicContact CD1-CE3 3.65Å; I66-W351 HydrophobicContact CD1-CH2 4.28Å; I66-W351 HydrophobicContact CD1-CZ3 3.18Å; I66-P353 HydrophobicContact CD1-CB 4.01Å
67	T	32.2	Very low	35.8	Very low	54 Å²	54	79 Å²	79	33%	0.331	42%	0.417	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-93.8	109.3	173.4	-39.7	0	0	0	0	108	R56 E71 T72	R56-T67 PolarHBondContact O-N 2.86Å; R56-T67 VanDerWaalsContact O-N 3.11Å; T67-E71 WeakPolarHBondContact CA-O 3.49Å; T67-T72 HydrophobicContact CG2-CG2 4.48Å
68	Y	29.5	Very low	36.2	Very low	74 Å²	74	79.9 Å²	79.9	29%	0.29	42%	0.419	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-127.9	125.8	176	-165.9	-104.4	0	0	0	108.8	D55 N70 E71 N348	D55-Y68 WeakPolarHBondContact OD1-CD2 3.44Å; Y68-N70 PolarHBondContact O-N 2.78Å; Y68-E71 PolarHBondContact N-O 2.94Å; Y68-E71 PolarHBondContact O-N 3.35Å; Y68-N348 VanDerWaalsContact OH-CB 3.32Å; Y68-N348 WeakPolarHBondContact OH-CB 3.42Å; Y68-N348 PolarHBondContact OH-ND2 3.43Å; Y68-N348 VanDerWaalsContact OH-ND2 3.15Å
69	L	32.3	Very low	36.7	Very low	130 Å²	130	79.6 Å²	79.6	68%	0.681	43%	0.427	S	S	*	.	T	Hydrogen-bonded Turn	trans	47.2	52.3	177.1	-70.9	165.4	0	0	0	114.2	E71	L69-E71 PolarHBondContact O-N 3.16Å; L69-E71 VanDerWaalsContact O-N 3.15Å
70	N	35	Very low	36.9	Very low	167 Å²	167	83.3 Å²	83.3	89%	0.893	45%	0.447	S	S	*	.	T	Hydrogen-bonded Turn	trans	65.2	3.3	-177.4	-93.8	-5.2	0	0	0	116.4	Y68	Y68-N70 PolarHBondContact O-N 2.78Å
71	E	31.2	Very low	37.1	Very low	99 Å²	99	77.6 Å²	77.6	46%	0.463	42%	0.422	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-104.8	128.4	173.6	-67.3	-174.6	164.9	0	0	110.5	T67 Y68 L69 Y73	T67-E71 WeakPolarHBondContact CA-O 3.49Å; Y68-E71 PolarHBondContact N-O 2.94Å; Y68-E71 PolarHBondContact O-N 3.35Å; L69-E71 PolarHBondContact O-N 3.16Å; L69-E71 VanDerWaalsContact O-N 3.15Å; E71-Y73 HydrophobicContact CB-CD2 4.37Å; E71-Y73 HydrophobicContact CB-CE2 3.68Å; E71-Y73 PolarHBondContact OE2-OH 3.4Å
72	T	33.7	Very low	37.4	Very low	88 Å²	88	75.5 Å²	75.5	54%	0.54	41%	0.406	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-97.2	115.3	175.7	-13.1	0	0	0	0	108.8	I66 T67	I66-T72 WeakPolarHBondContact O-CA 3.26Å; T67-T72 HydrophobicContact CG2-CG2 4.48Å
73	Y	37	Very low	37.6	Very low	86 Å²	86	71.6 Å²	71.6	34%	0.337	39%	0.385	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-99.8	111.6	175.8	-67.5	-91.6	0	0	0	109.1	E65 I66 E71	E65-Y73 CarbonylContact C-O 3.57Å; E65-Y73 VanDerWaalsContact CA-O 3.26Å; E65-Y73 WeakPolarHBondContact CA-O 3.41Å; I66-Y73 PolarHBondContact N-O 2.9Å; I66-Y73 PolarHBondContact O-N 3.5Å; E71-Y73 HydrophobicContact CB-CD2 4.37Å; E71-Y73 HydrophobicContact CB-CE2 3.68Å; E71-Y73 PolarHBondContact OE2-OH 3.4Å
74	S	35.3	Very low	38.1	Very low	57 Å²	57	72.8 Å²	72.8	40%	0.399	39%	0.389	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-100.9	118.5	172.6	60.4	0	0	0	0	110.4	M35 I64	M35-S74 WeakPolarHBondContact CE-O 3.43Å; I64-S74 CarbonylContact O-C 3.54Å; I64-S74 WeakPolarHBondContact O-CA 3.22Å
75	R	41.2	Very low	38.3	Very low	72 Å²	72	80.3 Å²	80.3	27%	0.272	42%	0.416	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-120.1	124.1	171.5	-164.9	176.5	-166.6	170.9	8	109.7	H29 T63 I64 I77	H29-R75 PolarHBondContact ND1-NH2 3.41Å; H29-R75 VanDerWaalsContact ND1-NH2 3.12Å; T63-R75 CarbonylContact C-O 3.57Å; T63-R75 WeakPolarHBondContact CA-O 3.19Å; I64-R75 PolarHBondContact N-O 2.85Å; I64-R75 PolarHBondContact O-N 3.46Å; R75-I77 PolarHBondContact O-N 3.37Å
76	P	35.4	Very low	39	Very low	50 Å²	50	79.7 Å²	79.7	33%	0.325	42%	0.42	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-72	119.3	174.3	1.6	13.2	0	0	0	109.3	Y28 D62 T63	Y28-P76 WeakPolarHBondContact CE1-O 3.49Å; Y28-P76 WeakPolarHBondContact OH-CB 3.12Å; Y28-P76 WeakPolarHBondContact OH-CD 3.4Å; Y28-P76 WeakPolarHBondContact OH-CG 3.47Å; Y28-P76 PolarHBondContact OH-O 2.74Å; D62-P76 CarbonylContact O-C 3.58Å; D62-P76 VanDerWaalsContact O-C 3.28Å; D62-P76 WeakPolarHBondContact O-CA 3.33Å; T63-P76 HydrophobicContact CG2-CB 3.91Å; T63-P76 HydrophobicContact CG2-CG 4.39Å
77	I	45.9	Very low	39.5	Very low	76 Å²	76	82.4 Å²	82.4	39%	0.39	43%	0.432	S	S	.	.			trans	-84	116	167.2	-43.2	179	0	0	0	106.1	D62 I64 R75 S79	D62-I77 PolarHBondContact O-N 2.87Å; I64-I77 HydrophobicContact CD1-CD1 3.4Å; I64-I77 VanDerWaalsContact CD1-CD1 3.4Å; I64-I77 HydrophobicContact CD1-CG1 3.72Å; I64-I77 HydrophobicContact CG1-CD1 3.28Å; I64-I77 HydrophobicContact CG1-CG1 3.48Å; I64-I77 VanDerWaalsContact CG1-CG1 3.48Å; R75-I77 PolarHBondContact O-N 3.37Å; I77-S79 PolarHBondContact O-N 3.32Å
78	N	42.8	Very low	40.9	Very low	79 Å²	79	80.4 Å²	80.4	42%	0.422	42%	0.421	S	S	.	.			trans	-74.1	100.8	162.6	-167.9	-5.2	0	0	0	108.1	D80 C81	N78-D80 PolarHBondContact O-N 2.85Å; N78-D80 VanDerWaalsContact O-N 3.15Å; N78-D80 WeakPolarHBondContact OD1-CB 3.38Å; N78-D80 PolarHBondContact OD1-N 3.37Å; N78-C81 PolarHBondContact O-N 2.96Å; N78-C81 VanDerWaalsContact O-N 3.15Å
79	S	43.5	Very low	42.9	Very low	88 Å²	88	80 Å²	80	62%	0.615	43%	0.426	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.2	-18.5	177	52.6	0	0	0	0	112.6	I77	I77-S79 PolarHBondContact O-N 3.32Å
80	D	40.4	Very low	44.9	Very low	128 Å²	128	77.8 Å²	77.8	68%	0.684	42%	0.418	S	S	*	.	T	Hydrogen-bonded Turn	trans	-89.1	10.6	176.8	-73.2	-33.1	0	0	0	115	N78 P82	N78-D80 PolarHBondContact O-N 2.85Å; N78-D80 VanDerWaalsContact O-N 3.15Å; N78-D80 WeakPolarHBondContact OD1-CB 3.38Å; N78-D80 PolarHBondContact OD1-N 3.37Å; D80-P82 WeakPolarHBondContact O-CD 3.35Å
81	C	43	Very low	46.8	Very low	14 Å²	14	69.9 Å²	69.9	10%	0.095	38%	0.375	C	S	.	.			trans	-87	97	172.5	-80.4	0	0	0	0	111.7	C25 N78 I83	C25-C81 HydrophobicContact CB-CB 4.08Å; C25-C81 WeakPolarHBondContact CB-SG 3.35Å; C25-C81 VanDerWaalsContact SG-CA 3.55Å; C25-C81 WeakPolarHBondContact SG-CB 3.41Å; C25-C81 CovalentContact SG-SG 2.03Å; C25-C81 PolarHBondContact SG-SG 2.92Å; N78-C81 PolarHBondContact O-N 2.96Å; N78-C81 VanDerWaalsContact O-N 3.15Å; C81-I83 PolarHBondContact O-N 2.75Å
82	P	41.7	Very low	49	Very low	72 Å²	72	65.5 Å²	65.5	47%	0.468	36%	0.355	S	S	.	.	H	α-helix	trans	-67.3	-3.2	-178	27.8	-37.3	0	0	0	114.8	D80 S86	D80-P82 WeakPolarHBondContact O-CD 3.35Å; P82-S86 PolarHBondContact O-N 2.72Å; P82-S86 VanDerWaalsContact O-N 3.15Å; P82-S86 PolarHBondContact O-OG 3.45Å
83	I	43.2	Very low	51.5	Low	12 Å²	12	66.3 Å²	66.3	6%	0.062	36%	0.355	C	S	.	.	H	α-helix	trans	-86.2	-37	-165	-62.8	148.3	0	0	0	111.6	I22 C25 C81 R85 S86 Q87	I22-I83 HydrophobicContact CB-CD1 3.78Å; I22-I83 HydrophobicContact CB-CG1 4.48Å; I22-I83 HydrophobicContact CG1-CD1 3.39Å; I22-I83 HydrophobicContact CG1-CG1 3.63Å; I22-I83 HydrophobicContact CG2-CD1 4.14Å; C25-I83 HydrophobicContact CB-CD1 3.64Å; C81-I83 PolarHBondContact O-N 2.75Å; I83-R85 VanDerWaalsContact C-N 3.28Å; I83-R85 PolarHBondContact O-N 3.31Å; I83-S86 PolarHBondContact O-OG 3.3Å; I83-Q87 HydrophobicContact CG2-CG 4.03Å; I83-Q87 VanDerWaalsContact O-CB 3.29Å; I83-Q87 WeakPolarHBondContact O-CB 3.34Å; I83-Q87 WeakPolarHBondContact O-CG 3.31Å; I83-Q87 PolarHBondContact O-N 2.84Å
84	L	44.7	Very low	53.9	Low	65 Å²	65	63 Å²	63	34%	0.34	34%	0.344	S	S	.	.	H	α-helix	trans	-62.9	-39.6	172.4	-90.5	101.3	0	0	0	110.9	S88	L84-S88 WeakPolarHBondContact O-CB 3.29Å; L84-S88 PolarHBondContact O-N 3.31Å
85	R	45.4	Very low	56.4	Low	180 Å²	180	60.4 Å²	60.4	68%	0.679	33%	0.326	S	S	*	.	H	α-helix	trans	-67.9	-47.5	-179.9	-165.2	173.6	-176.4	165.5	2.5	112	I83 T89	I83-R85 VanDerWaalsContact C-N 3.28Å; I83-R85 PolarHBondContact O-N 3.31Å; R85-T89 WeakPolarHBondContact O-CG2 3.29Å; R85-T89 PolarHBondContact O-N 2.86Å; R85-T89 PolarHBondContact O-OG1 2.81Å
86	S	46.7	Very low	58.7	Low	61 Å²	61	57.9 Å²	57.9	43%	0.427	32%	0.321	S	S	.	.	H	α-helix	trans	-73.3	-43.8	-177.5	53.6	0	0	0	0	113.1	P82 I83 T89	P82-S86 PolarHBondContact O-N 2.72Å; P82-S86 VanDerWaalsContact O-N 3.15Å; P82-S86 PolarHBondContact O-OG 3.45Å; I83-S86 PolarHBondContact O-OG 3.3Å; S86-T89 PolarHBondContact O-N 2.65Å; S86-T89 PolarHBondContact O-OG1 3.26Å
87	Q	50.3	Low	61.3	Low	79 Å²	79	59.1 Å²	59.1	37%	0.369	33%	0.327	S	S	.	.	H	α-helix	trans	-71.9	-34.1	-177.2	-65.5	-179.2	-20	0	0	112.9	I83	I83-Q87 HydrophobicContact CG2-CG 4.03Å; I83-Q87 VanDerWaalsContact O-CB 3.29Å; I83-Q87 WeakPolarHBondContact O-CB 3.34Å; I83-Q87 WeakPolarHBondContact O-CG 3.31Å; I83-Q87 PolarHBondContact O-N 2.84Å
88	S	61.7	Low	63.5	Low	12 Å²	12	55.5 Å²	55.5	8%	0.084	31%	0.309	C	S	.	.	H	α-helix	trans	-67.4	-39.3	175.1	-151.3	0	0	0	0	111.4	L84 V90 A91 H92	L84-S88 WeakPolarHBondContact O-CB 3.29Å; L84-S88 PolarHBondContact O-N 3.31Å; S88-V90 VanDerWaalsContact C-N 3.34Å; S88-V90 PolarHBondContact O-N 3.4Å; S88-A91 PolarHBondContact O-N 3.25Å; S88-H92 PolarHBondContact O-CD2 2.79Å; S88-H92 VanDerWaalsContact O-CG 3.26Å; S88-H92 PolarHBondContact O-N 3.28Å; S88-H92 PolarHBondContact OG-NE2 3.31Å
89	T	70.1	Confident	65.9	Low	64 Å²	64	52.7 Å²	52.7	39%	0.393	30%	0.295	S	S	.	.	H	α-helix	trans	-60.9	-38.4	-179.2	58.7	0	0	0	0	113.5	R85 S86 H92 I93	R85-T89 WeakPolarHBondContact O-CG2 3.29Å; R85-T89 PolarHBondContact O-N 2.86Å; R85-T89 PolarHBondContact O-OG1 2.81Å; S86-T89 PolarHBondContact O-N 2.65Å; S86-T89 PolarHBondContact O-OG1 3.26Å; T89-H92 PolarHBondContact O-N 3.25Å; T89-I93 WeakPolarHBondContact O-CB 3.37Å; T89-I93 WeakPolarHBondContact O-CD1 3.22Å; T89-I93 WeakPolarHBondContact O-CG1 3.14Å; T89-I93 PolarHBondContact O-N 3.4Å
90	V	74.7	Confident	68.3	Low	85 Å²	85	54.1 Å²	54.1	52%	0.515	29%	0.294	S	S	.	.	H	α-helix	trans	-63	-45.9	178.6	177.8	0	0	0	0	110.9	S88 I93 S94	S88-V90 VanDerWaalsContact C-N 3.34Å; S88-V90 PolarHBondContact O-N 3.4Å; V90-I93 PolarHBondContact O-N 3.2Å; V90-S94 VanDerWaalsContact O-CB 3.3Å; V90-S94 WeakPolarHBondContact O-CB 3.37Å; V90-S94 PolarHBondContact O-N 3.14Å; V90-S94 PolarHBondContact O-OG 2.77Å
91	A	74.3	Confident	70.8	Confident	0 Å²	0	50.4 Å²	50.4	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-66.2	-37.2	177.8	0	0	0	0	0	112.3	S88 S94 M95 W446 Q447	S88-A91 PolarHBondContact O-N 3.25Å; A91-S94 WeakPolarHBondContact CA-OG 3.38Å; A91-S94 PolarHBondContact O-OG 3.42Å; A91-M95 WeakPolarHBondContact O-CE 3.37Å; A91-M95 WeakPolarHBondContact O-CG 3.31Å; A91-M95 PolarHBondContact O-N 3.4Å; A91-W446 HydrophobicContact CB-CZ3 4.37Å; A91-Q447 HydrophobicContact CB-CB 4.44Å; A91-Q447 HydrophobicContact CB-CG 4.48Å
92	H	78.6	Confident	73.2	Confident	8 Å²	8	49.8 Å²	49.8	4%	0.037	27%	0.272	C	S	.	.	H	α-helix	trans	-67.4	-47.1	175.3	-60.9	-53.1	0	0	0	111.9	S88 T89 S94 M95 A96 F139 A142	S88-H92 PolarHBondContact O-CD2 2.79Å; S88-H92 VanDerWaalsContact O-CG 3.26Å; S88-H92 PolarHBondContact O-N 3.28Å; S88-H92 PolarHBondContact OG-NE2 3.31Å; T89-H92 PolarHBondContact O-N 3.25Å; H92-S94 VanDerWaalsContact C-N 3.26Å; H92-S94 PolarHBondContact O-N 3.43Å; H92-M95 PolarHBondContact O-N 3.43Å; H92-A96 PolarHBondContact O-N 3.19Å; H92-F139 HydrophobicContact CB-CD2 4.04Å; H92-F139 HydrophobicContact CB-CE2 3.98Å; H92-F139 WeakPolarHBondContact O-CD2 3.34Å; H92-A142 VanDerWaalsContact CE1-C 3.43Å; H92-A142 WeakPolarHBondContact CE1-CB 3.46Å; H92-A142 PolarHBondContact CE1-O 3.29Å
93	I	84.8	Confident	75.7	Confident	105 Å²	105	50.9 Å²	50.9	54%	0.538	27%	0.27	S	S	.	.	H	α-helix	trans	-60.5	-41.2	177.1	-67.7	164.9	0	0	0	109.7	T89 V90 M95 A96 V97	T89-I93 WeakPolarHBondContact O-CB 3.37Å; T89-I93 WeakPolarHBondContact O-CD1 3.22Å; T89-I93 WeakPolarHBondContact O-CG1 3.14Å; T89-I93 PolarHBondContact O-N 3.4Å; V90-I93 PolarHBondContact O-N 3.2Å; I93-M95 PolarHBondContact O-N 3.43Å; I93-A96 PolarHBondContact O-N 3.17Å; I93-V97 HydrophobicContact CG2-CG2 4.18Å; I93-V97 WeakPolarHBondContact O-CB 3.28Å; I93-V97 VanDerWaalsContact O-CG2 3.25Å; I93-V97 WeakPolarHBondContact O-CG2 3.32Å; I93-V97 PolarHBondContact O-N 2.68Å
94	S	87.3	Confident	78	Confident	17 Å²	17	52.5 Å²	52.5	12%	0.119	29%	0.285	C	S	.	.	H	α-helix	trans	-62.4	-44.1	178.2	74.2	0	0	0	0	111.6	V90 A91 H92 V97 A98 G450 A454	V90-S94 VanDerWaalsContact O-CB 3.3Å; V90-S94 WeakPolarHBondContact O-CB 3.37Å; V90-S94 PolarHBondContact O-N 3.14Å; V90-S94 PolarHBondContact O-OG 2.77Å; A91-S94 WeakPolarHBondContact CA-OG 3.38Å; A91-S94 PolarHBondContact O-OG 3.42Å; H92-S94 VanDerWaalsContact C-N 3.26Å; H92-S94 PolarHBondContact O-N 3.43Å; S94-V97 PolarHBondContact O-N 3.25Å; S94-A98 VanDerWaalsContact O-CB 3.27Å; S94-A98 WeakPolarHBondContact O-CB 3.36Å; S94-A98 PolarHBondContact O-N 2.88Å; S94-G450 PolarHBondContact OG-O 2.72Å; S94-A454 WeakPolarHBondContact O-CB 3.34Å
95	M	87.8	Confident	80.2	Confident	1 Å²	1	49.5 Å²	49.5	1%	0.005	27%	0.269	C	S	.	.	H	α-helix	trans	-64.6	-39.5	174.8	-70.4	-175.4	-72.1	0	0	112.9	A91 H92 I93 A98 S99 L138 F139 A142 W446 I453	A91-M95 WeakPolarHBondContact O-CE 3.37Å; A91-M95 WeakPolarHBondContact O-CG 3.31Å; A91-M95 PolarHBondContact O-N 3.4Å; H92-M95 PolarHBondContact O-N 3.43Å; I93-M95 PolarHBondContact O-N 3.43Å; M95-A98 WeakPolarHBondContact O-CB 3.33Å; M95-A98 PolarHBondContact O-N 2.96Å; M95-S99 PolarHBondContact O-N 3.11Å; M95-L138 HydrophobicContact SD-CB 3.76Å; M95-F139 HydrophobicContact CB-CB 4.01Å; M95-A142 HydrophobicContact CE-CB 4.26Å; M95-W446 HydrophobicContact CE-CH2 3.71Å; M95-W446 HydrophobicContact CE-CZ2 4.08Å; M95-I453 HydrophobicContact SD-CD1 4.47Å
96	A	89.8	Confident	82.4	Confident	20 Å²	20	42.5 Å²	42.5	17%	0.165	24%	0.244	C	C	.	.	H	α-helix	trans	-63.8	-47.8	175.6	0	0	0	0	0	111.7	H92 I93 A98 S99 I100 F139	H92-A96 PolarHBondContact O-N 3.19Å; I93-A96 PolarHBondContact O-N 3.17Å; A96-A98 VanDerWaalsContact C-N 3.3Å; A96-A98 PolarHBondContact O-N 3.46Å; A96-S99 PolarHBondContact O-N 3.44Å; A96-I100 WeakPolarHBondContact O-CG1 3.33Å; A96-I100 PolarHBondContact O-N 2.65Å; A96-F139 HydrophobicContact CB-CD1 4.48Å; A96-F139 HydrophobicContact CB-CD2 3.82Å; A96-F139 HydrophobicContact CB-CE2 3.89Å; A96-F139 HydrophobicContact CB-CG 4.11Å; A96-F139 HydrophobicContact CB-CZ 4.28Å
97	V	91.5	Very high	84.6	Confident	75 Å²	75	42.7 Å²	42.7	46%	0.455	24%	0.24	S	C	.	.	H	α-helix	trans	-59.6	-42.9	175.3	171.8	0	0	0	0	110.4	I93 S94 S99 I100 T101	I93-V97 HydrophobicContact CG2-CG2 4.18Å; I93-V97 WeakPolarHBondContact O-CB 3.28Å; I93-V97 VanDerWaalsContact O-CG2 3.25Å; I93-V97 WeakPolarHBondContact O-CG2 3.32Å; I93-V97 PolarHBondContact O-N 2.68Å; S94-V97 PolarHBondContact O-N 3.25Å; V97-S99 PolarHBondContact O-N 3.45Å; V97-I100 PolarHBondContact O-N 3.05Å; V97-T101 HydrophobicContact CG1-CG2 4.04Å; V97-T101 VanDerWaalsContact O-CB 3.32Å; V97-T101 WeakPolarHBondContact O-CB 3.24Å; V97-T101 WeakPolarHBondContact O-CG2 3.18Å; V97-T101 PolarHBondContact O-N 2.93Å; V97-T101 PolarHBondContact O-OG1 3.39Å
98	A	91.2	Very high	86.3	Confident	1 Å²	1	42.9 Å²	42.9	1%	0.008	24%	0.241	C	C	.	.	H	α-helix	trans	-58.5	-45.4	176.1	0	0	0	0	0	112.4	S94 M95 A96 T101 M102 N135 I453 A454	S94-A98 VanDerWaalsContact O-CB 3.27Å; S94-A98 WeakPolarHBondContact O-CB 3.36Å; S94-A98 PolarHBondContact O-N 2.88Å; M95-A98 WeakPolarHBondContact O-CB 3.33Å; M95-A98 PolarHBondContact O-N 2.96Å; A96-A98 VanDerWaalsContact C-N 3.3Å; A96-A98 PolarHBondContact O-N 3.46Å; A98-T101 PolarHBondContact O-OG1 2.9Å; A98-M102 WeakPolarHBondContact O-CB 3.44Å; A98-M102 VanDerWaalsContact O-CG 3.31Å; A98-M102 WeakPolarHBondContact O-CG 3.19Å; A98-M102 PolarHBondContact O-N 3.1Å; A98-M102 VanDerWaalsContact O-N 3.13Å; A98-N135 HydrophobicContact CB-CB 4.31Å; A98-I453 HydrophobicContact CB-CG2 4.09Å; A98-A454 HydrophobicContact CB-CB 4.27Å
99	S	93.7	Very high	87.4	Confident	20 Å²	20	42.4 Å²	42.4	14%	0.14	24%	0.238	C	C	.	.	H	α-helix	trans	-63.8	-50	178.5	-175.8	0	0	0	0	111.8	M95 A96 V97 M102 F103 S132 G136	M95-S99 PolarHBondContact O-N 3.11Å; A96-S99 PolarHBondContact O-N 3.44Å; V97-S99 PolarHBondContact O-N 3.45Å; S99-M102 PolarHBondContact O-N 2.91Å; S99-F103 WeakPolarHBondContact O-CB 3.36Å; S99-F103 PolarHBondContact O-N 2.98Å; S99-S132 WeakPolarHBondContact CB-O 3.43Å; S99-S132 PolarHBondContact O-OG 3.41Å; S99-S132 PolarHBondContact OG-O 3.48Å; S99-G136 PolarHBondContact OG-N 3.15Å
100	I	94.2	Very high	88.1	Confident	117 Å²	117	43.3 Å²	43.3	60%	0.6	24%	0.236	S	C	*	.	H	α-helix	trans	-63.5	-45.7	-177.7	-66.1	166.5	0	0	0	111	A96 V97 F103 A104	A96-I100 WeakPolarHBondContact O-CG1 3.33Å; A96-I100 PolarHBondContact O-N 2.65Å; V97-I100 PolarHBondContact O-N 3.05Å; I100-F103 WeakPolarHBondContact O-CB 3.49Å; I100-F103 PolarHBondContact O-N 3.07Å; I100-A104 WeakPolarHBondContact O-CB 3.21Å; I100-A104 PolarHBondContact O-N 3.29Å
101	T	92.6	Very high	88.6	Confident	51 Å²	51	46.3 Å²	46.3	31%	0.313	24%	0.243	S	C	.	.	H	α-helix	trans	-65.6	-42.2	-178.8	52.9	0	0	0	0	111.8	V97 A98 F103 A104 H105	V97-T101 HydrophobicContact CG1-CG2 4.04Å; V97-T101 VanDerWaalsContact O-CB 3.32Å; V97-T101 WeakPolarHBondContact O-CB 3.24Å; V97-T101 WeakPolarHBondContact O-CG2 3.18Å; V97-T101 PolarHBondContact O-N 2.93Å; V97-T101 PolarHBondContact O-OG1 3.39Å; A98-T101 PolarHBondContact O-OG1 2.9Å; T101-F103 VanDerWaalsContact C-N 3.34Å; T101-A104 PolarHBondContact O-N 3.49Å; T101-H105 WeakPolarHBondContact O-CB 3.26Å; T101-H105 PolarHBondContact O-N 3.42Å
102	M	92.9	Very high	88.8	Confident	0 Å²	0	50.7 Å²	50.7	0%	0	27%	0.269	C	S	.	.	H	α-helix	trans	-66.3	-36	174.5	-73.8	-66	-73.7	0	0	112.3	A98 S99 H105 F106 I128 N131 I460 I461	A98-M102 WeakPolarHBondContact O-CB 3.44Å; A98-M102 VanDerWaalsContact O-CG 3.31Å; A98-M102 WeakPolarHBondContact O-CG 3.19Å; A98-M102 PolarHBondContact O-N 3.1Å; A98-M102 VanDerWaalsContact O-N 3.13Å; S99-M102 PolarHBondContact O-N 2.91Å; M102-H105 PolarHBondContact O-N 3.37Å; M102-F106 PolarHBondContact O-N 3.48Å; M102-I128 HydrophobicContact CE-CB 4.23Å; M102-I128 HydrophobicContact CE-CG1 4.27Å; M102-I128 HydrophobicContact CE-CG2 3.8Å; M102-N131 HydrophobicContact CE-CB 3.75Å; M102-I460 HydrophobicContact CE-CG2 4.19Å; M102-I460 HydrophobicContact SD-CG2 4.33Å; M102-I461 HydrophobicContact CG-CD1 4.39Å; M102-I461 HydrophobicContact SD-CD1 3.98Å; M102-I461 HydrophobicContact SD-CG1 3.74Å
103	F	94.1	Very high	88.7	Confident	95 Å²	95	52.7 Å²	52.7	42%	0.417	28%	0.281	S	S	.	.	H	α-helix	trans	-65.3	-45.7	175	-167	-118.1	0	0	0	111.6	S99 I100 T101 H105 F106 I107 L129 S132	S99-F103 WeakPolarHBondContact O-CB 3.36Å; S99-F103 PolarHBondContact O-N 2.98Å; I100-F103 WeakPolarHBondContact O-CB 3.49Å; I100-F103 PolarHBondContact O-N 3.07Å; T101-F103 VanDerWaalsContact C-N 3.34Å; F103-H105 VanDerWaalsContact C-N 3.29Å; F103-H105 PolarHBondContact O-N 3.18Å; F103-F106 WeakPolarHBondContact O-CB 3.2Å; F103-F106 PolarHBondContact O-N 3.18Å; F103-I107 HydrophobicContact CD1-CD1 3.66Å; F103-I107 HydrophobicContact CD1-CG1 4.44Å; F103-I107 HydrophobicContact CE1-CD1 3.43Å; F103-I107 VanDerWaalsContact CE1-CD1 3.43Å; F103-I107 HydrophobicContact CE1-CG1 4.25Å; F103-I107 HydrophobicContact CG-CD1 4.46Å; F103-I107 HydrophobicContact CZ-CD1 4.03Å; F103-I107 HydrophobicContact CZ-CG1 4.44Å; F103-I107 WeakPolarHBondContact O-CG1 3.18Å; F103-I107 PolarHBondContact O-N 2.88Å; F103-L129 HydrophobicContact CE2-CD1 4.45Å; F103-S132 VanDerWaalsContact CB-OG 3.31Å; F103-S132 WeakPolarHBondContact CB-OG 3.33Å; F103-S132 PolarHBondContact N-OG 2.92Å
104	A	91.8	Very high	88.6	Confident	46 Å²	46	55.6 Å²	55.6	38%	0.38	29%	0.289	S	S	.	.	H	α-helix	trans	-59.9	-42.1	174.9	0	0	0	0	0	111.1	I100 T101 I107 M108	I100-A104 WeakPolarHBondContact O-CB 3.21Å; I100-A104 PolarHBondContact O-N 3.29Å; T101-A104 PolarHBondContact O-N 3.49Å; A104-I107 PolarHBondContact O-N 2.97Å; A104-M108 WeakPolarHBondContact O-CG 3.31Å; A104-M108 PolarHBondContact O-N 3.36Å
105	H	91.1	Very high	88.1	Confident	2 Å²	2	57.9 Å²	57.9	1%	0.009	31%	0.305	C	S	.	.	H	α-helix	trans	-62.2	-42.6	174.8	-170.6	66.7	0	0	0	112.3	T101 M102 F103 M108 V109 Y120 I461 T465	T101-H105 WeakPolarHBondContact O-CB 3.26Å; T101-H105 PolarHBondContact O-N 3.42Å; M102-H105 PolarHBondContact O-N 3.37Å; F103-H105 VanDerWaalsContact C-N 3.29Å; F103-H105 PolarHBondContact O-N 3.18Å; H105-M108 PolarHBondContact O-N 3.41Å; H105-V109 WeakPolarHBondContact O-CG2 3.31Å; H105-V109 PolarHBondContact O-N 3.3Å; H105-Y120 PolarHBondContact CE1-OH 3.5Å; H105-Y120 AromaticContact NE2-CE1 3.75Å; H105-Y120 AromaticContact NE2-CZ 3.77Å; H105-Y120 PolarHBondContact NE2-OH 3.04Å; H105-Y120 VanDerWaalsContact NE2-OH 3.12Å; H105-I461 HydrophobicContact CB-CD1 4.42Å; H105-I461 HydrophobicContact CB-CG1 4.1Å; H105-T465 PolarHBondContact CE1-OG1 2.85Å
106	F	92	Very high	87.7	Confident	33 Å²	33	58 Å²	58	15%	0.145	31%	0.306	C	S	.	.	H	α-helix	trans	-59.1	-48.1	173.1	172.3	-100.9	0	0	0	112.1	M102 F103 M108 V109 F110 I128 L129	M102-F106 PolarHBondContact O-N 3.48Å; F103-F106 WeakPolarHBondContact O-CB 3.2Å; F103-F106 PolarHBondContact O-N 3.18Å; F106-M108 VanDerWaalsContact C-N 3.31Å; F106-M108 PolarHBondContact O-N 3.24Å; F106-V109 PolarHBondContact O-N 3.14Å; F106-F110 HydrophobicContact CZ-CD2 4.46Å; F106-F110 WeakPolarHBondContact O-CB 3.33Å; F106-F110 PolarHBondContact O-N 3.47Å; F106-I128 HydrophobicContact CB-CG2 3.91Å; F106-L129 HydrophobicContact CD1-CD1 4.1Å; F106-L129 HydrophobicContact CD2-CB 3.89Å; F106-L129 HydrophobicContact CE1-CD1 4.04Å; F106-L129 HydrophobicContact CE2-CB 3.88Å; F106-L129 HydrophobicContact CE2-CD2 4.34Å; F106-L129 HydrophobicContact CE2-CG 4.49Å; F106-L129 HydrophobicContact CG-CB 4.37Å; F106-L129 HydrophobicContact CG-CD1 4.39Å; F106-L129 HydrophobicContact CZ-CB 4.35Å; F106-L129 HydrophobicContact CZ-CD1 4.29Å; F106-L129 HydrophobicContact CZ-CD2 4.1Å; F106-L129 HydrophobicContact CZ-CG 4.49Å
107	I	91.5	Very high	87.4	Confident	66 Å²	66	61.8 Å²	61.8	34%	0.338	32%	0.316	S	S	.	.	H	α-helix	trans	-57.6	-46.1	176.3	-71	172.1	0	0	0	110.1	F103 A104 V109 F110 F111	F103-I107 HydrophobicContact CD1-CD1 3.66Å; F103-I107 HydrophobicContact CD1-CG1 4.44Å; F103-I107 HydrophobicContact CE1-CD1 3.43Å; F103-I107 VanDerWaalsContact CE1-CD1 3.43Å; F103-I107 HydrophobicContact CE1-CG1 4.25Å; F103-I107 HydrophobicContact CG-CD1 4.46Å; F103-I107 HydrophobicContact CZ-CD1 4.03Å; F103-I107 HydrophobicContact CZ-CG1 4.44Å; F103-I107 WeakPolarHBondContact O-CG1 3.18Å; F103-I107 PolarHBondContact O-N 2.88Å; A104-I107 PolarHBondContact O-N 2.97Å; I107-V109 PolarHBondContact O-N 2.78Å; I107-F110 PolarHBondContact O-N 3.15Å; I107-F111 HydrophobicContact CB-CD2 4.26Å; I107-F111 HydrophobicContact CG1-CE2 4.5Å; I107-F111 HydrophobicContact CG2-CD2 3.75Å; I107-F111 HydrophobicContact CG2-CE2 4.41Å; I107-F111 WeakPolarHBondContact O-CB 3.43Å; I107-F111 WeakPolarHBondContact O-CD2 3.15Å; I107-F111 PolarHBondContact O-N 3.17Å
108	M	86.6	Confident	86.9	Confident	82 Å²	82	66 Å²	66	40%	0.404	32%	0.323	S	S	.	.	I	π-helix	trans	-59.3	-48.1	178.5	-74.3	-157.4	-63.4	0	0	112	A104 H105 F106 F110 V112	A104-M108 WeakPolarHBondContact O-CG 3.31Å; A104-M108 PolarHBondContact O-N 3.36Å; H105-M108 PolarHBondContact O-N 3.41Å; F106-M108 VanDerWaalsContact C-N 3.31Å; F106-M108 PolarHBondContact O-N 3.24Å; M108-F110 VanDerWaalsContact C-N 3.31Å; M108-F110 PolarHBondContact O-N 2.98Å; M108-V112 HydrophobicContact CB-CG2 4.23Å; M108-V112 HydrophobicContact CG-CG2 4.39Å; M108-V112 WeakPolarHBondContact O-CB 3.29Å; M108-V112 VanDerWaalsContact O-CG2 3.29Å; M108-V112 WeakPolarHBondContact O-CG2 3.17Å; M108-V112 PolarHBondContact O-N 2.94Å; M108-V112 VanDerWaalsContact O-N 3.12Å
109	V	85.3	Confident	86.4	Confident	2 Å²	2	66 Å²	66	1%	0.012	32%	0.324	C	S	.	.	I	π-helix	trans	-62.2	-39	179.1	171.8	0	0	0	0	111.7	H105 F106 I107 R117 Y120 F470	H105-V109 WeakPolarHBondContact O-CG2 3.31Å; H105-V109 PolarHBondContact O-N 3.3Å; F106-V109 PolarHBondContact O-N 3.14Å; I107-V109 PolarHBondContact O-N 2.78Å; V109-R117 PolarHBondContact O-N 3.34Å; V109-Y120 HydrophobicContact CG1-CD1 3.84Å; V109-Y120 HydrophobicContact CG1-CD2 3.79Å; V109-Y120 HydrophobicContact CG1-CE1 4.34Å; V109-Y120 HydrophobicContact CG1-CE2 4.27Å; V109-Y120 HydrophobicContact CG1-CG 3.55Å; V109-Y120 HydrophobicContact CG2-CD1 4.03Å; V109-Y120 HydrophobicContact CG2-CD2 4.2Å; V109-Y120 HydrophobicContact CG2-CE1 3.67Å; V109-Y120 HydrophobicContact CG2-CE2 3.84Å; V109-Y120 HydrophobicContact CG2-CG 4.3Å; V109-F470 HydrophobicContact CG2-CE2 4.4Å
110	F	85.2	Confident	85.9	Confident	83 Å²	83	65.1 Å²	65.1	36%	0.364	32%	0.317	S	S	.	.	I	π-helix	trans	-82.2	-40.9	-173.3	-162.2	-95	0	0	0	113.7	F106 I107 M108	F106-F110 HydrophobicContact CZ-CD2 4.46Å; F106-F110 WeakPolarHBondContact O-CB 3.33Å; F106-F110 PolarHBondContact O-N 3.47Å; I107-F110 PolarHBondContact O-N 3.15Å; M108-F110 VanDerWaalsContact C-N 3.31Å; M108-F110 PolarHBondContact O-N 2.98Å
111	F	85.1	Confident	85.4	Confident	148 Å²	148	60.2 Å²	60.2	65%	0.649	30%	0.296	S	S	*	.	I	π-helix	trans	-100.8	-30	-170.8	-67.7	-74.8	0	0	0	114.4	I107	I107-F111 HydrophobicContact CB-CD2 4.26Å; I107-F111 HydrophobicContact CG1-CE2 4.5Å; I107-F111 HydrophobicContact CG2-CD2 3.75Å; I107-F111 HydrophobicContact CG2-CE2 4.41Å; I107-F111 WeakPolarHBondContact O-CB 3.43Å; I107-F111 WeakPolarHBondContact O-CD2 3.15Å; I107-F111 PolarHBondContact O-N 3.17Å
112	V	78.6	Confident	85.1	Confident	92 Å²	92	61.6 Å²	61.6	56%	0.558	30%	0.301	S	S	*	.	I	π-helix	trans	-75.1	-44.7	-170.6	177.7	0	0	0	0	111.8	M108	M108-V112 HydrophobicContact CB-CG2 4.23Å; M108-V112 HydrophobicContact CG-CG2 4.39Å; M108-V112 WeakPolarHBondContact O-CB 3.29Å; M108-V112 VanDerWaalsContact O-CG2 3.29Å; M108-V112 WeakPolarHBondContact O-CG2 3.17Å; M108-V112 PolarHBondContact O-N 2.94Å; M108-V112 VanDerWaalsContact O-N 3.12Å
113	N	76.2	Confident	85	Confident	51 Å²	51	62 Å²	62	27%	0.273	30%	0.303	S	S	.	.			trans	-147.9	127.2	-173.9	-164.2	-26.4	0	0	0	112.8	S115 L116 R117 V473	N113-S115 PolarHBondContact O-N 3.41Å; N113-S115 WeakPolarHBondContact OD1-CB 3.25Å; N113-S115 PolarHBondContact OD1-N 3.45Å; N113-S115 PolarHBondContact OD1-OG 2.65Å; N113-L116 HydrophobicContact CB-CB 4.28Å; N113-L116 HydrophobicContact CB-CD1 4.09Å; N113-L116 HydrophobicContact CB-CG 4.01Å; N113-L116 WeakPolarHBondContact O-CB 3.46Å; N113-L116 PolarHBondContact O-N 3.28Å; N113-R117 PolarHBondContact O-N 2.88Å; N113-R117 VanDerWaalsContact O-N 3.15Å; N113-V473 HydrophobicContact CB-CG1 4.37Å; N113-V473 VanDerWaalsContact ND2-CG1 3.31Å; N113-V473 WeakPolarHBondContact ND2-CG1 3.13Å; N113-V473 PolarHBondContact ND2-O 3.27Å
114	K	82.4	Confident	84.8	Confident	165 Å²	165	57.4 Å²	57.4	72%	0.717	28%	0.283	S	S	*	.	H	α-helix	trans	-57.3	-31	173.8	-69.5	-178.3	-179	176	0	112.2	R118	K114-R118 WeakPolarHBondContact O-CB 3.38Å; K114-R118 PolarHBondContact O-N 3.16Å
115	S	77	Confident	84.7	Confident	66 Å²	66	55.7 Å²	55.7	46%	0.462	27%	0.269	S	S	.	.	H	α-helix	trans	-70.2	-35.8	176.5	-62.3	0	0	0	0	112.5	N113 R118 L119	N113-S115 PolarHBondContact O-N 3.41Å; N113-S115 WeakPolarHBondContact OD1-CB 3.25Å; N113-S115 PolarHBondContact OD1-N 3.45Å; N113-S115 PolarHBondContact OD1-OG 2.65Å; S115-R118 PolarHBondContact O-N 3.5Å; S115-L119 WeakPolarHBondContact O-CB 3.45Å; S115-L119 PolarHBondContact O-N 3.43Å
116	L	78.3	Confident	84.8	Confident	2 Å²	2	57.4 Å²	57.4	1%	0.01	28%	0.277	C	S	.	.	H	α-helix	trans	-66.8	-46.4	173.3	-72.7	176.4	0	0	0	110.6	N113 R118 L119 Y120 F470 V473	N113-L116 HydrophobicContact CB-CB 4.28Å; N113-L116 HydrophobicContact CB-CD1 4.09Å; N113-L116 HydrophobicContact CB-CG 4.01Å; N113-L116 WeakPolarHBondContact O-CB 3.46Å; N113-L116 PolarHBondContact O-N 3.28Å; L116-R118 PolarHBondContact O-N 3.13Å; L116-L119 WeakPolarHBondContact O-CB 3.43Å; L116-L119 PolarHBondContact O-N 3.44Å; L116-Y120 WeakPolarHBondContact O-CD2 3.42Å; L116-Y120 PolarHBondContact O-N 2.86Å; L116-F470 HydrophobicContact CD1-CE2 3.94Å; L116-F470 HydrophobicContact CD1-CZ 4.01Å; L116-F470 HydrophobicContact CD2-CD2 3.54Å; L116-F470 HydrophobicContact CD2-CE2 3.76Å; L116-F470 HydrophobicContact CD2-CG 4.01Å; L116-F470 HydrophobicContact CD2-CZ 4.38Å; L116-F470 HydrophobicContact CG-CE2 4.46Å; L116-V473 HydrophobicContact CD2-CB 3.9Å; L116-V473 HydrophobicContact CD2-CG1 3.69Å; L116-V473 HydrophobicContact CG-CB 4.39Å; L116-V473 HydrophobicContact CG-CG1 3.62Å
117	R	83.8	Confident	84.9	Confident	101 Å²	101	55.9 Å²	55.9	38%	0.381	27%	0.271	S	S	.	.	H	α-helix	trans	-56.4	-40	173.7	-171.2	175.3	67.5	-172.1	4.6	111.8	V109 N113 G121	V109-R117 PolarHBondContact O-N 3.34Å; N113-R117 PolarHBondContact O-N 2.88Å; N113-R117 VanDerWaalsContact O-N 3.15Å; R117-G121 PolarHBondContact O-N 3.47Å
118	R	80.2	Confident	85	Confident	162 Å²	162	52.8 Å²	52.8	61%	0.611	26%	0.255	S	S	*	.	H	α-helix	trans	-65	-44.8	173.9	-173.3	179	-179.7	168.4	2.1	111.5	K114 S115 L116 G121 R416	K114-R118 WeakPolarHBondContact O-CB 3.38Å; K114-R118 PolarHBondContact O-N 3.16Å; S115-R118 PolarHBondContact O-N 3.5Å; L116-R118 PolarHBondContact O-N 3.13Å; R118-G121 PolarHBondContact O-N 3.42Å; R118-R416 PolarHBondContact O-NH2 3.25Å
119	L	80.8	Confident	85.4	Confident	2 Å²	2	50.6 Å²	50.6	1%	0.01	25%	0.245	C	C	.	.	H	α-helix	trans	-61.7	-42.3	-179.9	176.4	66.1	0	0	0	112.2	S115 L116 D412 R416 M419 P469	S115-L119 WeakPolarHBondContact O-CB 3.45Å; S115-L119 PolarHBondContact O-N 3.43Å; L116-L119 WeakPolarHBondContact O-CB 3.43Å; L116-L119 PolarHBondContact O-N 3.44Å; L119-D412 HydrophobicContact CD1-CB 3.93Å; L119-R416 VanDerWaalsContact O-CD 3.28Å; L119-R416 WeakPolarHBondContact O-CD 3.24Å; L119-R416 WeakPolarHBondContact O-CG 3.33Å; L119-R416 PolarHBondContact O-NE 3.38Å; L119-M419 HydrophobicContact CD2-CE 4.44Å; L119-P469 HydrophobicContact CD1-CB 4.14Å; L119-P469 HydrophobicContact CD2-CB 3.88Å; L119-P469 HydrophobicContact CD2-CG 4.22Å
120	Y	84.1	Confident	85.8	Confident	2 Å²	2	51.4 Å²	51.4	1%	0.008	25%	0.248	C	C	.	.	H	α-helix	trans	-75.3	-40.3	179.6	-80.5	-118.6	0	0	0	111.1	H105 V109 L116 L124 I128 F464 F470	H105-Y120 PolarHBondContact CE1-OH 3.5Å; H105-Y120 AromaticContact NE2-CE1 3.75Å; H105-Y120 AromaticContact NE2-CZ 3.77Å; H105-Y120 PolarHBondContact NE2-OH 3.04Å; H105-Y120 VanDerWaalsContact NE2-OH 3.12Å; V109-Y120 HydrophobicContact CG1-CD1 3.84Å; V109-Y120 HydrophobicContact CG1-CD2 3.79Å; V109-Y120 HydrophobicContact CG1-CE1 4.34Å; V109-Y120 HydrophobicContact CG1-CE2 4.27Å; V109-Y120 HydrophobicContact CG1-CG 3.55Å; V109-Y120 HydrophobicContact CG2-CD1 4.03Å; V109-Y120 HydrophobicContact CG2-CD2 4.2Å; V109-Y120 HydrophobicContact CG2-CE1 3.67Å; V109-Y120 HydrophobicContact CG2-CE2 3.84Å; V109-Y120 HydrophobicContact CG2-CG 4.3Å; L116-Y120 WeakPolarHBondContact O-CD2 3.42Å; L116-Y120 PolarHBondContact O-N 2.86Å; Y120-L124 HydrophobicContact CD1-CB 4.37Å; Y120-L124 HydrophobicContact CD1-CD2 3.45Å; Y120-L124 VanDerWaalsContact CD1-CD2 3.45Å; Y120-L124 HydrophobicContact CD1-CG 3.8Å; Y120-L124 HydrophobicContact CE1-CD2 3.99Å; Y120-L124 HydrophobicContact CE1-CG 4.47Å; Y120-L124 HydrophobicContact CG-CD2 3.87Å; Y120-L124 HydrophobicContact CG-CG 4.48Å; Y120-L124 WeakPolarHBondContact O-CB 3.25Å; Y120-I128 HydrophobicContact CD1-CD1 3.48Å; Y120-I128 VanDerWaalsContact CD1-CD1 3.48Å; Y120-I128 HydrophobicContact CE1-CD1 3.36Å; Y120-F464 AromaticContact CE1-CD2 3.82Å; Y120-F464 HydrophobicContact CE1-CD2 3.82Å; Y120-F464 HydrophobicContact CE1-CE2 4.37Å; Y120-F464 WeakPolarHBondContact OH-CB 3.31Å; Y120-F470 AromaticContact CE2-CD2 3.94Å; Y120-F470 HydrophobicContact CE2-CD2 3.94Å; Y120-F470 HydrophobicContact CE2-CE2 4.27Å; Y120-F470 WeakPolarHBondContact OH-CD2 3.48Å
121	G	83.8	Confident	86.2	Confident	14 Å²	14	47.7 Å²	47.7	14%	0.144	23%	0.232	C	C	.	.	H	α-helix	trans	69.9	178.8	-171.1	0	0	0	0	0	112.1	R117 R118 S125	R117-G121 PolarHBondContact O-N 3.47Å; R118-G121 PolarHBondContact O-N 3.42Å; G121-S125 WeakPolarHBondContact O-CB 3.48Å; G121-S125 PolarHBondContact O-N 3.02Å; G121-S125 PolarHBondContact O-OG 3.31Å
122	N	86.7	Confident	86.7	Confident	80 Å²	80	40.8 Å²	40.8	43%	0.428	20%	0.202	S	C	.	.	H	α-helix	trans	-71.9	-45.2	-171.3	-64.4	-13.9	0	0	0	112.1	S125 L126 I324	N122-S125 PolarHBondContact O-N 3.15Å; N122-L126 WeakPolarHBondContact O-CG 3.32Å; N122-L126 PolarHBondContact O-N 2.86Å; N122-I324 HydrophobicContact CB-CD1 3.96Å; N122-I324 HydrophobicContact CB-CG1 4.43Å
123	C	89.4	Confident	87.5	Confident	7 Å²	7	40.1 Å²	40.1	5%	0.047	20%	0.195	C	C	.	.	H	α-helix	trans	-60.7	-49.3	-178.1	-59.5	0	0	0	0	112	S125 L126 I127 V323 F420	C123-S125 VanDerWaalsContact C-N 3.32Å; C123-S125 PolarHBondContact O-N 3.4Å; C123-L126 PolarHBondContact O-N 3.36Å; C123-I127 WeakPolarHBondContact O-CD1 3.38Å; C123-I127 VanDerWaalsContact O-CG1 3.24Å; C123-I127 WeakPolarHBondContact O-CG1 3.35Å; C123-I127 PolarHBondContact O-N 2.97Å; C123-V323 VanDerWaalsContact SG-CG1 3.55Å; C123-F420 HydrophobicContact CB-CZ 4.17Å
124	L	90.1	Very high	88.2	Confident	0 Å²	0	38.1 Å²	38.1	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-65.5	-37.4	-179.7	-164.6	65.4	0	0	0	112	Y120 I127 I128 M419 F420 I423 F464	Y120-L124 HydrophobicContact CD1-CB 4.37Å; Y120-L124 HydrophobicContact CD1-CD2 3.45Å; Y120-L124 VanDerWaalsContact CD1-CD2 3.45Å; Y120-L124 HydrophobicContact CD1-CG 3.8Å; Y120-L124 HydrophobicContact CE1-CD2 3.99Å; Y120-L124 HydrophobicContact CE1-CG 4.47Å; Y120-L124 HydrophobicContact CG-CD2 3.87Å; Y120-L124 HydrophobicContact CG-CG 4.48Å; Y120-L124 WeakPolarHBondContact O-CB 3.25Å; L124-I127 PolarHBondContact O-N 3.22Å; L124-I128 HydrophobicContact CG-CD1 4.32Å; L124-I128 WeakPolarHBondContact O-CD1 3.04Å; L124-I128 VanDerWaalsContact O-CG1 3.28Å; L124-I128 WeakPolarHBondContact O-CG1 3.23Å; L124-I128 PolarHBondContact O-N 3Å; L124-I128 VanDerWaalsContact O-N 3.07Å; L124-M419 HydrophobicContact CD2-CB 4.1Å; L124-M419 HydrophobicContact CD2-SD 3.73Å; L124-F420 HydrophobicContact CB-CE1 4.39Å; L124-F420 HydrophobicContact CB-CZ 4.13Å; L124-F420 HydrophobicContact CD1-CD1 4.17Å; L124-F420 HydrophobicContact CD1-CE1 3.95Å; L124-F420 HydrophobicContact CD1-CZ 4.33Å; L124-I423 HydrophobicContact CD1-CD1 3.62Å; L124-F464 HydrophobicContact CD1-CE2 4.02Å; L124-F464 HydrophobicContact CD1-CZ 4.3Å; L124-F464 HydrophobicContact CD2-CE2 4.07Å; L124-F464 HydrophobicContact CG-CE2 4.29Å
125	S	90.9	Very high	88.6	Confident	10 Å²	10	30.4 Å²	30.4	7%	0.07	15%	0.151	C	C	.	.	H	α-helix	trans	-64.4	-42.3	176.1	-56.6	0	0	0	0	111.7	G121 N122 C123 I128 L129	G121-S125 WeakPolarHBondContact O-CB 3.48Å; G121-S125 PolarHBondContact O-N 3.02Å; G121-S125 PolarHBondContact O-OG 3.31Å; N122-S125 PolarHBondContact O-N 3.15Å; C123-S125 VanDerWaalsContact C-N 3.32Å; C123-S125 PolarHBondContact O-N 3.4Å; S125-I128 PolarHBondContact O-N 2.81Å; S125-L129 PolarHBondContact O-N 3.12Å
126	L	92.5	Very high	89.3	Confident	37 Å²	37	27.7 Å²	27.7	19%	0.194	13%	0.133	C	C	.	.	H	α-helix	trans	-64.3	-41.9	175.2	-75	172.7	0	0	0	112	N122 C123 I128 L129 F130 I324	N122-L126 WeakPolarHBondContact O-CG 3.32Å; N122-L126 PolarHBondContact O-N 2.86Å; C123-L126 PolarHBondContact O-N 3.36Å; L126-I128 VanDerWaalsContact C-N 3.33Å; L126-I128 PolarHBondContact O-N 3.39Å; L126-L129 PolarHBondContact O-N 3.41Å; L126-F130 HydrophobicContact CD2-CZ 4.43Å; L126-F130 WeakPolarHBondContact O-CB 3.37Å; L126-F130 WeakPolarHBondContact O-CG 3.14Å; L126-F130 PolarHBondContact O-N 2.91Å; L126-I324 HydrophobicContact CD1-CB 4.43Å; L126-I324 HydrophobicContact CD1-CG1 3.93Å; L126-I324 HydrophobicContact CD1-CG2 4.04Å
127	I	93.9	Very high	89.8	Confident	1 Å²	1	28.2 Å²	28.2	1%	0.005	14%	0.137	C	C	.	.	H	α-helix	trans	-59.4	-44.7	176.2	-68.4	162.1	0	0	0	111	C123 L124 F130 N131 I183 G186 I187 F420 I423	C123-I127 WeakPolarHBondContact O-CD1 3.38Å; C123-I127 VanDerWaalsContact O-CG1 3.24Å; C123-I127 WeakPolarHBondContact O-CG1 3.35Å; C123-I127 PolarHBondContact O-N 2.97Å; L124-I127 PolarHBondContact O-N 3.22Å; I127-F130 PolarHBondContact O-N 2.95Å; I127-N131 WeakPolarHBondContact O-CB 3.42Å; I127-N131 VanDerWaalsContact O-CG 3.29Å; I127-N131 PolarHBondContact O-N 2.93Å; I127-I183 HydrophobicContact CG2-CG2 4.23Å; I127-G186 VanDerWaalsContact CD1-C 3.43Å; I127-I187 HydrophobicContact CD1-CG1 3.96Å; I127-F420 HydrophobicContact CD1-CD1 4.2Å; I127-F420 HydrophobicContact CD1-CE1 3.65Å; I127-I423 HydrophobicContact CG2-CD1 4.22Å; I127-I423 HydrophobicContact CG2-CG2 4.19Å
128	I	93.2	Very high	89.8	Confident	1 Å²	1	24.1 Å²	24.1	1%	0.005	12%	0.122	C	C	.	.	H	α-helix	trans	-65	-42.2	179.5	-66	163.6	0	0	0	110.7	M102 F106 Y120 L124 S125 L126 N131 S132 F464	M102-I128 HydrophobicContact CE-CB 4.23Å; M102-I128 HydrophobicContact CE-CG1 4.27Å; M102-I128 HydrophobicContact CE-CG2 3.8Å; F106-I128 HydrophobicContact CB-CG2 3.91Å; Y120-I128 HydrophobicContact CD1-CD1 3.48Å; Y120-I128 VanDerWaalsContact CD1-CD1 3.48Å; Y120-I128 HydrophobicContact CE1-CD1 3.36Å; L124-I128 HydrophobicContact CG-CD1 4.32Å; L124-I128 WeakPolarHBondContact O-CD1 3.04Å; L124-I128 VanDerWaalsContact O-CG1 3.28Å; L124-I128 WeakPolarHBondContact O-CG1 3.23Å; L124-I128 PolarHBondContact O-N 3Å; L124-I128 VanDerWaalsContact O-N 3.07Å; S125-I128 PolarHBondContact O-N 2.81Å; L126-I128 VanDerWaalsContact C-N 3.33Å; L126-I128 PolarHBondContact O-N 3.39Å; I128-N131 PolarHBondContact O-N 2.72Å; I128-S132 PolarHBondContact O-N 2.85Å; I128-F464 HydrophobicContact CD1-CD2 4.5Å; I128-F464 HydrophobicContact CD1-CE2 4.48Å
129	L	94.8	Very high	90.1	Very high	37 Å²	37	18.2 Å²	18.2	19%	0.194	10%	0.101	C	C	.	.	H	α-helix	trans	-62.1	-49.2	175.5	178.9	62	0	0	0	111.4	F103 F106 S125 L126 N131 S132 L133	F103-L129 HydrophobicContact CE2-CD1 4.45Å; F106-L129 HydrophobicContact CD1-CD1 4.1Å; F106-L129 HydrophobicContact CD2-CB 3.89Å; F106-L129 HydrophobicContact CE1-CD1 4.04Å; F106-L129 HydrophobicContact CE2-CB 3.88Å; F106-L129 HydrophobicContact CE2-CD2 4.34Å; F106-L129 HydrophobicContact CE2-CG 4.49Å; F106-L129 HydrophobicContact CG-CB 4.37Å; F106-L129 HydrophobicContact CG-CD1 4.39Å; F106-L129 HydrophobicContact CZ-CB 4.35Å; F106-L129 HydrophobicContact CZ-CD1 4.29Å; F106-L129 HydrophobicContact CZ-CD2 4.1Å; F106-L129 HydrophobicContact CZ-CG 4.49Å; S125-L129 PolarHBondContact O-N 3.12Å; L126-L129 PolarHBondContact O-N 3.41Å; L129-N131 VanDerWaalsContact C-N 3.32Å; L129-N131 PolarHBondContact O-N 3.02Å; L129-S132 WeakPolarHBondContact O-CB 3.45Å; L129-S132 PolarHBondContact O-N 2.63Å; L129-S132 VanDerWaalsContact O-N 3.16Å; L129-L133 HydrophobicContact CG-CD1 4.37Å; L129-L133 WeakPolarHBondContact O-CG 3.35Å; L129-L133 PolarHBondContact O-N 2.97Å
130	F	95.5	Very high	90.2	Very high	19 Å²	19	23.1 Å²	23.1	8%	0.083	12%	0.122	C	C	.	.	H	α-helix	trans	-65.9	-33.3	179.6	-68.5	-13.1	0	0	0	112.5	L126 I127 L133 H134 L179 S182 I183 I327 V328	L126-F130 HydrophobicContact CD2-CZ 4.43Å; L126-F130 WeakPolarHBondContact O-CB 3.37Å; L126-F130 WeakPolarHBondContact O-CG 3.14Å; L126-F130 PolarHBondContact O-N 2.91Å; I127-F130 PolarHBondContact O-N 2.95Å; F130-L133 HydrophobicContact CD1-CD1 4.23Å; F130-L133 PolarHBondContact O-N 3.23Å; F130-H134 WeakPolarHBondContact O-CB 3.44Å; F130-H134 PolarHBondContact O-N 3.38Å; F130-L179 HydrophobicContact CB-CD2 4.32Å; F130-L179 HydrophobicContact CD1-CD2 4.12Å; F130-L179 HydrophobicContact CG-CD2 4.28Å; F130-S182 VanDerWaalsContact CD2-CB 3.48Å; F130-I183 HydrophobicContact CB-CD1 4.26Å; F130-I183 HydrophobicContact CB-CG1 3.68Å; F130-I327 HydrophobicContact CD2-CG2 4.46Å; F130-I327 HydrophobicContact CE2-CG2 3.82Å; F130-V328 HydrophobicContact CZ-CG2 4.26Å
131	N	93.7	Very high	89.8	Confident	4 Å²	4	23.5 Å²	23.5	2%	0.021	13%	0.125	C	C	.	.	H	α-helix	trans	-62.6	-44.2	170.3	-81.1	-12	0	0	0	112.1	M102 I127 I128 L129 H134 N135 I183 H427	M102-N131 HydrophobicContact CE-CB 3.75Å; I127-N131 WeakPolarHBondContact O-CB 3.42Å; I127-N131 VanDerWaalsContact O-CG 3.29Å; I127-N131 PolarHBondContact O-N 2.93Å; I128-N131 PolarHBondContact O-N 2.72Å; L129-N131 VanDerWaalsContact C-N 3.32Å; L129-N131 PolarHBondContact O-N 3.02Å; N131-H134 PolarHBondContact O-N 3.36Å; N131-N135 WeakPolarHBondContact O-CB 3.39Å; N131-N135 PolarHBondContact O-N 3.34Å; N131-N135 PolarHBondContact O-ND2 2.97Å; N131-I183 WeakPolarHBondContact OD1-CD1 3.34Å; N131-I183 VanDerWaalsContact OD1-CG1 3.3Å; N131-I183 WeakPolarHBondContact OD1-CG1 3.46Å; N131-I183 WeakPolarHBondContact OD1-CG2 3.41Å; N131-H427 PolarHBondContact ND2-CE1 3.39Å; N131-H427 VanDerWaalsContact ND2-CE1 3.28Å; N131-H427 PolarHBondContact ND2-NE2 2.88Å; N131-H427 PolarHBondContact OD1-NE2 3.19Å; N131-H427 VanDerWaalsContact OD1-NE2 3.09Å
132	S	94.8	Very high	89.2	Confident	3 Å²	3	22.9 Å²	22.9	2%	0.021	12%	0.119	C	C	.	.	H	α-helix	trans	-60.4	-46.6	175.4	175.3	0	0	0	0	111.6	S99 F103 I128 L129 G136	S99-S132 WeakPolarHBondContact CB-O 3.43Å; S99-S132 PolarHBondContact O-OG 3.41Å; S99-S132 PolarHBondContact OG-O 3.48Å; F103-S132 VanDerWaalsContact CB-OG 3.31Å; F103-S132 WeakPolarHBondContact CB-OG 3.33Å; F103-S132 PolarHBondContact N-OG 2.92Å; I128-S132 PolarHBondContact O-N 2.85Å; L129-S132 WeakPolarHBondContact O-CB 3.45Å; L129-S132 PolarHBondContact O-N 2.63Å; L129-S132 VanDerWaalsContact O-N 3.16Å; S132-G136 PolarHBondContact O-N 3.47Å
133	L	94.5	Very high	88.6	Confident	78 Å²	78	24.1 Å²	24.1	41%	0.408	12%	0.118	S	C	.	.	H	α-helix	trans	-63.7	-45.1	177	-67.6	177.8	0	0	0	111.9	L129 F130 N135 G136 V137 L179	L129-L133 HydrophobicContact CG-CD1 4.37Å; L129-L133 WeakPolarHBondContact O-CG 3.35Å; L129-L133 PolarHBondContact O-N 2.97Å; F130-L133 HydrophobicContact CD1-CD1 4.23Å; F130-L133 PolarHBondContact O-N 3.23Å; L133-N135 VanDerWaalsContact C-N 3.35Å; L133-N135 PolarHBondContact O-N 3.27Å; L133-G136 CarbonylContact O-C 3.59Å; L133-G136 WeakPolarHBondContact O-CA 3.12Å; L133-G136 PolarHBondContact O-N 3.43Å; L133-G136 VanDerWaalsContact O-N 3.11Å; L133-V137 VanDerWaalsContact O-CG2 3.29Å; L133-V137 WeakPolarHBondContact O-CG2 3.45Å; L133-V137 PolarHBondContact O-N 3.44Å; L133-L179 HydrophobicContact CB-CD1 3.92Å; L133-L179 HydrophobicContact CB-CD2 4.09Å; L133-L179 HydrophobicContact CD1-CD2 4.33Å
134	H	92.6	Very high	87.5	Confident	9 Å²	9	25 Å²	25	4%	0.042	12%	0.122	C	C	.	.	H	α-helix	trans	-59	-46.9	-180	175.3	-95.4	0	0	0	111.1	F130 N131 G136 V137 L138 L179 I183	F130-H134 WeakPolarHBondContact O-CB 3.44Å; F130-H134 PolarHBondContact O-N 3.38Å; N131-H134 PolarHBondContact O-N 3.36Å; H134-G136 VanDerWaalsContact C-N 3.3Å; H134-G136 PolarHBondContact O-N 2.9Å; H134-V137 PolarHBondContact O-N 3.41Å; H134-L138 WeakPolarHBondContact CE1-CD1 3.47Å; H134-L138 WeakPolarHBondContact O-CG 3.48Å; H134-L138 PolarHBondContact O-N 2.87Å; H134-L179 HydrophobicContact CB-CB 4.02Å; H134-L179 HydrophobicContact CB-CD1 4.32Å; H134-I183 HydrophobicContact CB-CD1 4.01Å
135	N	91.1	Very high	86	Confident	4 Å²	4	26.4 Å²	26.4	2%	0.021	13%	0.131	C	C	.	.	H	α-helix	trans	-64.4	-36.3	176.5	-65.4	-13.6	0	0	0	112.1	A98 N131 L133 F139 I453 S457	A98-N135 HydrophobicContact CB-CB 4.31Å; N131-N135 WeakPolarHBondContact O-CB 3.39Å; N131-N135 PolarHBondContact O-N 3.34Å; N131-N135 PolarHBondContact O-ND2 2.97Å; L133-N135 VanDerWaalsContact C-N 3.35Å; L133-N135 PolarHBondContact O-N 3.27Å; N135-F139 WeakPolarHBondContact O-CB 3.38Å; N135-F139 PolarHBondContact O-N 3.33Å; N135-I453 HydrophobicContact CB-CG2 4.43Å; N135-I453 WeakPolarHBondContact OD1-CG2 3.12Å; N135-S457 PolarHBondContact ND2-OG 2.96Å; N135-S457 VanDerWaalsContact ND2-OG 3.11Å
136	G	90.6	Very high	84.6	Confident	9 Å²	9	26.5 Å²	26.5	9%	0.093	13%	0.132	C	C	.	.	H	α-helix	trans	-65.3	-45.1	175	0	0	0	0	0	112	S99 S132 L133 H134 F139 F140	S99-G136 PolarHBondContact OG-N 3.15Å; S132-G136 PolarHBondContact O-N 3.47Å; L133-G136 CarbonylContact O-C 3.59Å; L133-G136 WeakPolarHBondContact O-CA 3.12Å; L133-G136 PolarHBondContact O-N 3.43Å; L133-G136 VanDerWaalsContact O-N 3.11Å; H134-G136 VanDerWaalsContact C-N 3.3Å; H134-G136 PolarHBondContact O-N 2.9Å; G136-F139 WeakPolarHBondContact O-CB 3.41Å; G136-F139 PolarHBondContact O-N 3.27Å; G136-F140 WeakPolarHBondContact O-CD2 3.33Å; G136-F140 PolarHBondContact O-N 3.28Å
137	V	88.3	Confident	83.2	Confident	13 Å²	13	26.9 Å²	26.9	8%	0.079	14%	0.136	C	C	.	.	H	α-helix	trans	-64.6	-42.3	177.6	175	0	0	0	0	111	L133 H134 F139 F140 S141 M172 L175 T176 L179	L133-V137 VanDerWaalsContact O-CG2 3.29Å; L133-V137 WeakPolarHBondContact O-CG2 3.45Å; L133-V137 PolarHBondContact O-N 3.44Å; H134-V137 PolarHBondContact O-N 3.41Å; V137-F139 VanDerWaalsContact C-N 3.33Å; V137-F139 PolarHBondContact O-N 3.39Å; V137-F140 PolarHBondContact O-N 3.28Å; V137-S141 VanDerWaalsContact O-CB 3.29Å; V137-S141 WeakPolarHBondContact O-CB 3.35Å; V137-S141 PolarHBondContact O-N 2.89Å; V137-S141 PolarHBondContact O-OG 3.12Å; V137-M172 HydrophobicContact CG1-SD 3.95Å; V137-L175 HydrophobicContact CB-CD2 4.47Å; V137-L175 HydrophobicContact CG1-CB 4.25Å; V137-L175 HydrophobicContact CG1-CD2 4.14Å; V137-L175 HydrophobicContact CG1-CG 4.24Å; V137-L175 HydrophobicContact CG2-CD2 3.43Å; V137-L175 VanDerWaalsContact CG2-CD2 3.43Å; V137-L175 HydrophobicContact CG2-CG 3.88Å; V137-T176 VanDerWaalsContact CG1-OG1 3.31Å; V137-T176 WeakPolarHBondContact CG1-OG1 3.5Å; V137-L179 HydrophobicContact CB-CD1 4.47Å; V137-L179 HydrophobicContact CG2-CD1 3.9Å
138	L	85.1	Confident	81.4	Confident	15 Å²	15	27.9 Å²	27.9	8%	0.079	14%	0.141	C	C	.	.	H	α-helix	trans	-62.2	-39.3	173.2	-76	178.9	0	0	0	112.7	M95 H134 S141 A142 T176 Y449 I453	M95-L138 HydrophobicContact SD-CB 3.76Å; H134-L138 WeakPolarHBondContact CE1-CD1 3.47Å; H134-L138 WeakPolarHBondContact O-CG 3.48Å; H134-L138 PolarHBondContact O-N 2.87Å; L138-S141 WeakPolarHBondContact CA-OG 3.34Å; L138-S141 PolarHBondContact O-OG 3.46Å; L138-S141 VanDerWaalsContact O-OG 3.08Å; L138-A142 VanDerWaalsContact O-CB 3.29Å; L138-A142 WeakPolarHBondContact O-CB 3.36Å; L138-A142 PolarHBondContact O-N 2.69Å; L138-T176 HydrophobicContact CD2-CG2 3.67Å; L138-T176 HydrophobicContact CG-CG2 4.22Å; L138-Y449 HydrophobicContact CD1-CE1 4.22Å; L138-I453 HydrophobicContact CD1-CD1 3.61Å
139	F	86.7	Confident	79.4	Confident	38 Å²	38	29.8 Å²	29.8	17%	0.167	16%	0.155	C	C	.	.	H	α-helix	trans	-62.2	-51.6	173.3	167.3	-103.9	0	0	0	110.8	H92 M95 A96 N135 G136 V137 A142 Y143	H92-F139 HydrophobicContact CB-CD2 4.04Å; H92-F139 HydrophobicContact CB-CE2 3.98Å; H92-F139 WeakPolarHBondContact O-CD2 3.34Å; M95-F139 HydrophobicContact CB-CB 4.01Å; A96-F139 HydrophobicContact CB-CD1 4.48Å; A96-F139 HydrophobicContact CB-CD2 3.82Å; A96-F139 HydrophobicContact CB-CE2 3.89Å; A96-F139 HydrophobicContact CB-CG 4.11Å; A96-F139 HydrophobicContact CB-CZ 4.28Å; N135-F139 WeakPolarHBondContact O-CB 3.38Å; N135-F139 PolarHBondContact O-N 3.33Å; G136-F139 WeakPolarHBondContact O-CB 3.41Å; G136-F139 PolarHBondContact O-N 3.27Å; V137-F139 VanDerWaalsContact C-N 3.33Å; V137-F139 PolarHBondContact O-N 3.39Å; F139-A142 PolarHBondContact O-N 3.17Å; F139-Y143 HydrophobicContact CE1-CG 4.35Å; F139-Y143 AromaticContact CE2-CD2 3.84Å; F139-Y143 HydrophobicContact CE2-CD2 3.84Å; F139-Y143 AromaticContact CE2-CG 3.88Å; F139-Y143 HydrophobicContact CE2-CG 3.88Å; F139-Y143 HydrophobicContact CZ-CD1 4.08Å; F139-Y143 AromaticContact CZ-CD2 3.89Å; F139-Y143 HydrophobicContact CZ-CD2 3.89Å; F139-Y143 HydrophobicContact CZ-CE2 4.45Å; F139-Y143 AromaticContact CZ-CG 3.68Å; F139-Y143 HydrophobicContact CZ-CG 3.68Å; F139-Y143 WeakPolarHBondContact O-CB 3.43Å; F139-Y143 PolarHBondContact O-N 3.16Å
140	F	81.2	Confident	77.5	Confident	104 Å²	104	34.2 Å²	34.2	46%	0.456	17%	0.172	S	C	.	.	H	α-helix	trans	-62.4	-46.2	-179.2	-78.7	-58.4	0	0	0	112.2	G136 V137 A142 Y143 I144 M172	G136-F140 WeakPolarHBondContact O-CD2 3.33Å; G136-F140 PolarHBondContact O-N 3.28Å; V137-F140 PolarHBondContact O-N 3.28Å; F140-A142 PolarHBondContact O-N 3.35Å; F140-Y143 PolarHBondContact O-N 2.92Å; F140-I144 HydrophobicContact CB-CD1 3.82Å; F140-I144 HydrophobicContact CD1-CD1 3.78Å; F140-I144 HydrophobicContact CD1-CG1 4.42Å; F140-I144 HydrophobicContact CG-CD1 4.23Å; F140-I144 WeakPolarHBondContact O-CB 3.34Å; F140-I144 VanDerWaalsContact O-CD1 3.27Å; F140-I144 WeakPolarHBondContact O-CD1 3.26Å; F140-I144 WeakPolarHBondContact O-CG1 3.33Å; F140-I144 PolarHBondContact O-N 3.18Å; F140-M172 HydrophobicContact CB-CE 4.26Å
141	S	75.5	Confident	75.6	Confident	11 Å²	11	39.7 Å²	39.7	8%	0.077	20%	0.203	C	C	.	.	H	α-helix	trans	-59.5	-34.3	179	71.2	0	0	0	0	111.5	V137 L138 P145 C360	V137-S141 VanDerWaalsContact O-CB 3.29Å; V137-S141 WeakPolarHBondContact O-CB 3.35Å; V137-S141 PolarHBondContact O-N 2.89Å; V137-S141 PolarHBondContact O-OG 3.12Å; L138-S141 WeakPolarHBondContact CA-OG 3.34Å; L138-S141 PolarHBondContact O-OG 3.46Å; L138-S141 VanDerWaalsContact O-OG 3.08Å; S141-P145 WeakPolarHBondContact O-CD 3.48Å; S141-P145 WeakPolarHBondContact O-CG 3.46Å; S141-C360 VanDerWaalsContact O-CB 3.25Å; S141-C360 WeakPolarHBondContact O-CB 3.45Å
142	A	72.3	Confident	73.6	Confident	0 Å²	0	42.7 Å²	42.7	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-91.5	-34	-178.7	0	0	0	0	0	113.3	H92 M95 L138 F139 F140 S146 I358 W446	H92-A142 VanDerWaalsContact CE1-C 3.43Å; H92-A142 WeakPolarHBondContact CE1-CB 3.46Å; H92-A142 PolarHBondContact CE1-O 3.29Å; M95-A142 HydrophobicContact CE-CB 4.26Å; L138-A142 VanDerWaalsContact O-CB 3.29Å; L138-A142 WeakPolarHBondContact O-CB 3.36Å; L138-A142 PolarHBondContact O-N 2.69Å; F139-A142 PolarHBondContact O-N 3.17Å; F140-A142 PolarHBondContact O-N 3.35Å; A142-S146 WeakPolarHBondContact O-CB 3.44Å; A142-S146 PolarHBondContact O-OG 3.24Å; A142-I358 WeakPolarHBondContact CA-O 3.39Å; A142-I358 VanDerWaalsContact CB-O 3.26Å; A142-I358 WeakPolarHBondContact CB-O 3.43Å; A142-W446 HydrophobicContact CB-CH2 3.54Å; A142-W446 HydrophobicContact CB-CZ2 3.71Å
143	Y	74.4	Confident	71.6	Confident	107 Å²	107	47 Å²	47	42%	0.42	24%	0.244	S	C	.	.	H	α-helix	trans	-76.7	-38.8	-176.7	-178.4	-97.4	0	0	0	112.9	F139 F140 S146 T147	F139-Y143 HydrophobicContact CE1-CG 4.35Å; F139-Y143 AromaticContact CE2-CD2 3.84Å; F139-Y143 HydrophobicContact CE2-CD2 3.84Å; F139-Y143 AromaticContact CE2-CG 3.88Å; F139-Y143 HydrophobicContact CE2-CG 3.88Å; F139-Y143 HydrophobicContact CZ-CD1 4.08Å; F139-Y143 AromaticContact CZ-CD2 3.89Å; F139-Y143 HydrophobicContact CZ-CD2 3.89Å; F139-Y143 HydrophobicContact CZ-CE2 4.45Å; F139-Y143 AromaticContact CZ-CG 3.68Å; F139-Y143 HydrophobicContact CZ-CG 3.68Å; F139-Y143 WeakPolarHBondContact O-CB 3.43Å; F139-Y143 PolarHBondContact O-N 3.16Å; F140-Y143 PolarHBondContact O-N 2.92Å; Y143-S146 VanDerWaalsContact C-OG 3.32Å; Y143-S146 WeakPolarHBondContact CA-OG 3.34Å; Y143-S146 PolarHBondContact O-OG 3.42Å; Y143-T147 WeakPolarHBondContact CE1-OG1 3.41Å; Y143-T147 VanDerWaalsContact O-CB 3.32Å; Y143-T147 WeakPolarHBondContact O-CB 3.4Å; Y143-T147 PolarHBondContact O-N 3.38Å; Y143-T147 PolarHBondContact O-OG1 3.02Å
144	I	66.3	Low	69.5	Low	24 Å²	24	45.5 Å²	45.5	12%	0.123	24%	0.236	C	C	.	.	H	α-helix	trans	-71.6	-52.7	-174.1	-63.2	150.8	0	0	0	111.8	F140 S146 T147 I148 F167	F140-I144 HydrophobicContact CB-CD1 3.82Å; F140-I144 HydrophobicContact CD1-CD1 3.78Å; F140-I144 HydrophobicContact CD1-CG1 4.42Å; F140-I144 HydrophobicContact CG-CD1 4.23Å; F140-I144 WeakPolarHBondContact O-CB 3.34Å; F140-I144 VanDerWaalsContact O-CD1 3.27Å; F140-I144 WeakPolarHBondContact O-CD1 3.26Å; F140-I144 WeakPolarHBondContact O-CG1 3.33Å; F140-I144 PolarHBondContact O-N 3.18Å; I144-S146 VanDerWaalsContact C-N 3.26Å; I144-S146 PolarHBondContact O-N 2.77Å; I144-T147 PolarHBondContact O-N 3.28Å; I144-I148 HydrophobicContact CG2-CD1 3.23Å; I144-I148 HydrophobicContact CG2-CG1 4.01Å; I144-I148 WeakPolarHBondContact O-CB 3.27Å; I144-I148 WeakPolarHBondContact O-CG1 3.45Å; I144-I148 PolarHBondContact O-N 3.19Å; I144-F167 HydrophobicContact CB-CD1 3.99Å; I144-F167 HydrophobicContact CB-CE1 4.03Å; I144-F167 HydrophobicContact CD1-CD1 3.52Å; I144-F167 HydrophobicContact CD1-CE1 3.18Å; I144-F167 HydrophobicContact CD1-CZ 4.29Å; I144-F167 HydrophobicContact CG1-CD1 4.06Å; I144-F167 HydrophobicContact CG1-CE1 3.64Å; I144-F167 HydrophobicContact CG2-CD1 3.3Å; I144-F167 HydrophobicContact CG2-CE1 3.45Å; I144-F167 VanDerWaalsContact CG2-CE1 3.45Å
145	P	59.2	Low	67.5	Low	30 Å²	30	47.3 Å²	47.3	20%	0.195	26%	0.257	C	S	.	.	H	α-helix	trans	-60.6	-39.1	179.6	-22.8	35.4	0	0	0	111.8	S141 S149 C360	S141-P145 WeakPolarHBondContact O-CD 3.48Å; S141-P145 WeakPolarHBondContact O-CG 3.46Å; P145-S149 VanDerWaalsContact O-CB 3.25Å; P145-S149 WeakPolarHBondContact O-CB 2.87Å; P145-S149 PolarHBondContact O-N 2.85Å; P145-S149 PolarHBondContact O-OG 3.26Å; P145-C360 HydrophobicContact CG-CB 3.93Å; P145-C360 WeakPolarHBondContact CG-SG 3.35Å
146	S	61	Low	65.8	Low	13 Å²	13	51 Å²	51	9%	0.091	28%	0.277	C	S	.	.	H	α-helix	trans	-60.7	-51.8	174.9	55.2	0	0	0	0	110.9	A142 Y143 I144 I148 S149 F150	A142-S146 WeakPolarHBondContact O-CB 3.44Å; A142-S146 PolarHBondContact O-OG 3.24Å; Y143-S146 VanDerWaalsContact C-OG 3.32Å; Y143-S146 WeakPolarHBondContact CA-OG 3.34Å; Y143-S146 PolarHBondContact O-OG 3.42Å; I144-S146 VanDerWaalsContact C-N 3.26Å; I144-S146 PolarHBondContact O-N 2.77Å; S146-I148 PolarHBondContact O-N 3.49Å; S146-S149 PolarHBondContact O-N 3.04Å; S146-S149 PolarHBondContact O-OG 3.11Å; S146-F150 WeakPolarHBondContact O-CD2 3.29Å; S146-F150 PolarHBondContact O-N 3.33Å
147	T	62.3	Low	63.9	Low	45 Å²	45	52.2 Å²	52.2	28%	0.276	28%	0.281	S	S	.	.	H	α-helix	trans	-61.9	-41.4	179.9	-54.7	0	0	0	0	113.1	Y143 I144 F150 N151	Y143-T147 WeakPolarHBondContact CE1-OG1 3.41Å; Y143-T147 VanDerWaalsContact O-CB 3.32Å; Y143-T147 WeakPolarHBondContact O-CB 3.4Å; Y143-T147 PolarHBondContact O-N 3.38Å; Y143-T147 PolarHBondContact O-OG1 3.02Å; I144-T147 PolarHBondContact O-N 3.28Å; T147-F150 PolarHBondContact O-N 3.48Å; T147-N151 PolarHBondContact O-N 2.56Å
148	I	55.8	Low	62	Low	21 Å²	21	54.8 Å²	54.8	11%	0.108	30%	0.297	C	S	.	.	H	α-helix	trans	-64.5	-46.5	177.8	-70.5	165.6	0	0	0	110.6	I144 S146 F150 N151 M152 I157 F160	I144-I148 HydrophobicContact CG2-CD1 3.23Å; I144-I148 HydrophobicContact CG2-CG1 4.01Å; I144-I148 WeakPolarHBondContact O-CB 3.27Å; I144-I148 WeakPolarHBondContact O-CG1 3.45Å; I144-I148 PolarHBondContact O-N 3.19Å; S146-I148 PolarHBondContact O-N 3.49Å; I148-F150 PolarHBondContact O-N 3.37Å; I148-F150 VanDerWaalsContact O-N 3.12Å; I148-N151 PolarHBondContact O-N 3.24Å; I148-N151 VanDerWaalsContact O-N 3.14Å; I148-M152 HydrophobicContact CG2-CB 4.33Å; I148-M152 HydrophobicContact CG2-CG 4.37Å; I148-M152 HydrophobicContact CG2-SD 3.78Å; I148-M152 WeakPolarHBondContact O-CB 3.46Å; I148-M152 PolarHBondContact O-N 3.29Å; I148-I157 HydrophobicContact CG2-CG1 4.1Å; I148-I157 HydrophobicContact CG2-CG2 4.47Å; I148-F160 HydrophobicContact CD1-CD1 3.49Å; I148-F160 VanDerWaalsContact CD1-CD1 3.49Å; I148-F160 HydrophobicContact CD1-CE1 3.15Å; I148-F160 HydrophobicContact CD1-CG 4.41Å; I148-F160 HydrophobicContact CD1-CZ 3.83Å; I148-F160 HydrophobicContact CG1-CD1 4.45Å; I148-F160 HydrophobicContact CG1-CE1 4.24Å
149	S	51.6	Low	60.4	Low	42 Å²	42	60.7 Å²	60.7	29%	0.294	32%	0.319	S	S	.	.	H	α-helix	trans	-59.8	-25.4	-179.6	70.8	0	0	0	0	113.3	P145 S146	P145-S149 VanDerWaalsContact O-CB 3.25Å; P145-S149 WeakPolarHBondContact O-CB 2.87Å; P145-S149 PolarHBondContact O-N 2.85Å; P145-S149 PolarHBondContact O-OG 3.26Å; S146-S149 PolarHBondContact O-N 3.04Å; S146-S149 PolarHBondContact O-OG 3.11Å
150	F	55.1	Low	58.6	Low	129 Å²	129	61 Å²	61	57%	0.566	32%	0.32	S	S	*	.	H	α-helix	trans	-90.3	-22.5	179.1	-71.2	-59.1	0	0	0	114.5	S146 T147 I148	S146-F150 WeakPolarHBondContact O-CD2 3.29Å; S146-F150 PolarHBondContact O-N 3.33Å; T147-F150 PolarHBondContact O-N 3.48Å; I148-F150 PolarHBondContact O-N 3.37Å; I148-F150 VanDerWaalsContact O-N 3.12Å
151	N	55.6	Low	57.1	Low	135 Å²	135	59.8 Å²	59.8	72%	0.722	32%	0.322	S	S	*	.	H	α-helix	trans	-112.1	-15.6	-171.3	-80.1	-8	0	0	0	114.7	T147 I148	T147-N151 PolarHBondContact O-N 2.56Å; I148-N151 PolarHBondContact O-N 3.24Å; I148-N151 VanDerWaalsContact O-N 3.14Å
152	M	50.6	Low	55.9	Low	67 Å²	67	67.5 Å²	67.5	33%	0.33	35%	0.349	S	S	.	.	S	Bend	trans	-111.4	142.5	-171.8	-76	-172.2	178.7	0	0	112.3	I148 D156 I157 F160	I148-M152 HydrophobicContact CG2-CB 4.33Å; I148-M152 HydrophobicContact CG2-CG 4.37Å; I148-M152 HydrophobicContact CG2-SD 3.78Å; I148-M152 WeakPolarHBondContact O-CB 3.46Å; I148-M152 PolarHBondContact O-N 3.29Å; M152-D156 HydrophobicContact CB-CB 3.88Å; M152-D156 HydrophobicContact CG-CB 4.08Å; M152-D156 HydrophobicContact SD-CB 4.15Å; M152-I157 HydrophobicContact CB-CD1 4.47Å; M152-I157 HydrophobicContact CB-CG1 3.63Å; M152-F160 HydrophobicContact CE-CD2 3.85Å; M152-F160 HydrophobicContact CE-CE2 4.27Å; M152-F160 HydrophobicContact CE-CG 4.42Å; M152-F160 HydrophobicContact SD-CB 4.15Å; M152-F160 HydrophobicContact SD-CD2 4.26Å; M152-F160 HydrophobicContact SD-CG 4.25Å
153	T	54.3	Low	55.1	Low	94 Å²	94	72.8 Å²	72.8	58%	0.577	37%	0.373	S	S	*	.			trans	-71.5	159	170.5	70.6	0	0	0	0	110	G155 D156 I157	T153-G155 PolarHBondContact O-N 2.81Å; T153-D156 PolarHBondContact N-OD2 3.42Å; T153-D156 WeakPolarHBondContact O-CB 3.24Å; T153-D156 PolarHBondContact O-N 3.46Å; T153-D156 PolarHBondContact OG1-OD2 3.34Å; T153-I157 PolarHBondContact O-N 3.36Å; T153-I157 VanDerWaalsContact O-N 3.08Å
154	N	50.5	Low	54	Low	46 Å²	46	70.4 Å²	70.4	25%	0.246	37%	0.368	C	S	.	.	H	α-helix	trans	-51.7	-35.9	-176.3	-68.3	-28.6	0	0	0	114.5	I59 T158	I59-N154 WeakPolarHBondContact CB-OD1 3.22Å; I59-N154 WeakPolarHBondContact CD1-OD1 3.4Å; I59-N154 WeakPolarHBondContact CG1-OD1 3.48Å; I59-N154 PolarHBondContact N-ND2 3.49Å; I59-N154 PolarHBondContact N-OD1 3.35Å; I59-N154 PolarHBondContact O-ND2 3.2Å; N154-T158 PolarHBondContact O-N 3.04Å; N154-T158 PolarHBondContact O-OG1 2.98Å; N154-T158 VanDerWaalsContact O-OG1 3.04Å
155	G	49.9	Very low	53	Low	47 Å²	47	74.5 Å²	74.5	49%	0.485	39%	0.394	S	S	.	.	H	α-helix	trans	-68.4	-35.8	177.8	0	0	0	0	0	112.6	T153 T158 Y159	T153-G155 PolarHBondContact O-N 2.81Å; G155-T158 PolarHBondContact O-OG1 3.42Å; G155-T158 VanDerWaalsContact O-OG1 3.07Å; G155-Y159 WeakPolarHBondContact O-CB 3.19Å; G155-Y159 PolarHBondContact O-N 3.48Å
156	D	54.7	Low	52.2	Low	81 Å²	81	80.4 Å²	80.4	43%	0.433	42%	0.417	S	S	.	.	H	α-helix	trans	-74.7	-36.2	179.2	-57.9	-40.9	0	0	0	111.3	M152 T153 F160	M152-D156 HydrophobicContact CB-CB 3.88Å; M152-D156 HydrophobicContact CG-CB 4.08Å; M152-D156 HydrophobicContact SD-CB 4.15Å; T153-D156 PolarHBondContact N-OD2 3.42Å; T153-D156 WeakPolarHBondContact O-CB 3.24Å; T153-D156 PolarHBondContact O-N 3.46Å; T153-D156 PolarHBondContact OG1-OD2 3.34Å; D156-F160 WeakPolarHBondContact O-CB 3.44Å; D156-F160 PolarHBondContact O-N 2.89Å
157	I	51	Low	51.8	Low	35 Å²	35	83.4 Å²	83.4	18%	0.179	43%	0.428	C	S	.	.	H	α-helix	trans	-63.1	-45.1	177.9	-62.2	172.4	0	0	0	110.8	I59 I148 M152 T153 F160 T161	I59-I157 HydrophobicContact CD1-CD1 4.31Å; I148-I157 HydrophobicContact CG2-CG1 4.1Å; I148-I157 HydrophobicContact CG2-CG2 4.47Å; M152-I157 HydrophobicContact CB-CD1 4.47Å; M152-I157 HydrophobicContact CB-CG1 3.63Å; T153-I157 PolarHBondContact O-N 3.36Å; T153-I157 VanDerWaalsContact O-N 3.08Å; I157-F160 PolarHBondContact O-N 3.1Å; I157-T161 HydrophobicContact CG2-CG2 4.49Å; I157-T161 WeakPolarHBondContact O-CB 3.21Å; I157-T161 WeakPolarHBondContact O-CG2 3.31Å; I157-T161 PolarHBondContact O-N 2.9Å; I157-T161 PolarHBondContact O-OG1 3.46Å
158	T	49.4	Very low	51.9	Low	66 Å²	66	84.4 Å²	84.4	41%	0.405	43%	0.432	S	S	.	.	H	α-helix	trans	-70	-38.7	-178.4	45.2	0	0	0	0	112.1	N154 G155 T161 R162	N154-T158 PolarHBondContact O-N 3.04Å; N154-T158 PolarHBondContact O-OG1 2.98Å; N154-T158 VanDerWaalsContact O-OG1 3.04Å; G155-T158 PolarHBondContact O-OG1 3.42Å; G155-T158 VanDerWaalsContact O-OG1 3.07Å; T158-T161 PolarHBondContact O-OG1 3Å; T158-R162 WeakPolarHBondContact O-CB 3.28Å; T158-R162 PolarHBondContact O-N 3.45Å
159	Y	50.8	Low	52.3	Low	139 Å²	139	85.2 Å²	85.2	55%	0.545	44%	0.439	S	S	.	.	H	α-helix	trans	-65.4	-47.5	172.6	-176.9	-107.4	0	0	0	112	G155 T161 R162 E163	G155-Y159 WeakPolarHBondContact O-CB 3.19Å; G155-Y159 PolarHBondContact O-N 3.48Å; Y159-T161 PolarHBondContact O-N 3.31Å; Y159-R162 PolarHBondContact O-N 3.1Å; Y159-E163 HydrophobicContact CD2-CG 4.44Å; Y159-E163 HydrophobicContact CE2-CG 4.02Å; Y159-E163 WeakPolarHBondContact CE2-OE1 3.38Å; Y159-E163 PolarHBondContact O-N 3.37Å; Y159-E163 VanDerWaalsContact O-N 3.08Å; Y159-E163 PolarHBondContact OH-OE1 2.99Å; Y159-E163 PolarHBondContact OH-OE2 3.47Å
160	F	48.4	Very low	53.1	Low	45 Å²	45	89.1 Å²	89.1	20%	0.197	45%	0.448	C	S	.	.	H	α-helix	trans	-63	-43.4	-178.5	-173.2	-81.7	0	0	0	112.4	I148 M152 D156 I157 R162 N164 F167	I148-F160 HydrophobicContact CD1-CD1 3.49Å; I148-F160 VanDerWaalsContact CD1-CD1 3.49Å; I148-F160 HydrophobicContact CD1-CE1 3.15Å; I148-F160 HydrophobicContact CD1-CG 4.41Å; I148-F160 HydrophobicContact CD1-CZ 3.83Å; I148-F160 HydrophobicContact CG1-CD1 4.45Å; I148-F160 HydrophobicContact CG1-CE1 4.24Å; M152-F160 HydrophobicContact CE-CD2 3.85Å; M152-F160 HydrophobicContact CE-CE2 4.27Å; M152-F160 HydrophobicContact CE-CG 4.42Å; M152-F160 HydrophobicContact SD-CB 4.15Å; M152-F160 HydrophobicContact SD-CD2 4.26Å; M152-F160 HydrophobicContact SD-CG 4.25Å; D156-F160 WeakPolarHBondContact O-CB 3.44Å; D156-F160 PolarHBondContact O-N 2.89Å; I157-F160 PolarHBondContact O-N 3.1Å; F160-R162 VanDerWaalsContact C-N 3.33Å; F160-R162 PolarHBondContact O-N 3.2Å; F160-N164 VanDerWaalsContact CD2-ND2 3.26Å; F160-N164 WeakPolarHBondContact CD2-ND2 3.28Å; F160-N164 HydrophobicContact CE1-CB 4.32Å; F160-N164 WeakPolarHBondContact CE2-ND2 3.46Å; F160-N164 VanDerWaalsContact CZ-ND2 3.31Å; F160-N164 WeakPolarHBondContact CZ-ND2 3.16Å; F160-N164 VanDerWaalsContact O-CB 3.28Å; F160-N164 WeakPolarHBondContact O-CB 3.29Å; F160-N164 PolarHBondContact O-N 3.41Å; F160-N164 VanDerWaalsContact O-N 3.17Å; F160-N164 PolarHBondContact O-ND2 3.46Å; F160-F167 HydrophobicContact CE1-CB 4.2Å; F160-F167 HydrophobicContact CE1-CD1 4.23Å; F160-F167 HydrophobicContact CE1-CD2 4.4Å; F160-F167 HydrophobicContact CE1-CG 4.02Å; F160-F167 HydrophobicContact CZ-CD2 4.43Å; F160-F167 HydrophobicContact CZ-CE2 4.43Å; F160-F167 HydrophobicContact CZ-CG 4.4Å; F160-F167 HydrophobicContact CZ-CZ 4.47Å
161	T	51.1	Low	54	Low	79 Å²	79	86.9 Å²	86.9	49%	0.485	44%	0.438	S	S	.	.	H	α-helix	trans	-68.9	-29.5	179	45.6	0	0	0	0	113	I157 T158 Y159	I157-T161 HydrophobicContact CG2-CG2 4.49Å; I157-T161 WeakPolarHBondContact O-CB 3.21Å; I157-T161 WeakPolarHBondContact O-CG2 3.31Å; I157-T161 PolarHBondContact O-N 2.9Å; I157-T161 PolarHBondContact O-OG1 3.46Å; T158-T161 PolarHBondContact O-OG1 3Å; Y159-T161 PolarHBondContact O-N 3.31Å
162	R	50.6	Low	55	Low	172 Å²	172	81.7 Å²	81.7	65%	0.649	41%	0.409	S	S	*	.	H	α-helix	trans	-78.6	-41.4	179.4	-168.1	179.1	-172.4	151.8	8.1	113.1	E54 T158 Y159 F160	E54-R162 IonicContact OE1-CZ 3.23Å; E54-R162 IonicContact OE1-NH1 2.89Å; E54-R162 PolarHBondContact OE1-NH1 3.26Å; E54-R162 IonicContact OE1-NH2 3.36Å; E54-R162 PolarHBondContact OE1-NH2 3.06Å; T158-R162 WeakPolarHBondContact O-CB 3.28Å; T158-R162 PolarHBondContact O-N 3.45Å; Y159-R162 PolarHBondContact O-N 3.1Å; F160-R162 VanDerWaalsContact C-N 3.33Å; F160-R162 PolarHBondContact O-N 3.2Å
163	E	53.7	Low	56.2	Low	111 Å²	111	78.9 Å²	78.9	52%	0.519	40%	0.396	S	S	.	.	H	α-helix	trans	-83.6	-32.2	-176.6	-74	-160.9	165.3	0	0	113.7	Y159 V165	Y159-E163 HydrophobicContact CD2-CG 4.44Å; Y159-E163 HydrophobicContact CE2-CG 4.02Å; Y159-E163 WeakPolarHBondContact CE2-OE1 3.38Å; Y159-E163 PolarHBondContact O-N 3.37Å; Y159-E163 VanDerWaalsContact O-N 3.08Å; Y159-E163 PolarHBondContact OH-OE1 2.99Å; Y159-E163 PolarHBondContact OH-OE2 3.47Å; E163-V165 PolarHBondContact O-N 2.91Å; E163-V165 VanDerWaalsContact O-N 3.08Å
164	N	53	Low	57.4	Low	58 Å²	58	76.9 Å²	76.9	31%	0.31	38%	0.381	S	S	.	.			trans	-89.8	81.1	-174.6	-73.5	-46.3	0	0	0	111.7	F160 F166 F167 N168	F160-N164 VanDerWaalsContact CD2-ND2 3.26Å; F160-N164 WeakPolarHBondContact CD2-ND2 3.28Å; F160-N164 HydrophobicContact CE1-CB 4.32Å; F160-N164 WeakPolarHBondContact CE2-ND2 3.46Å; F160-N164 VanDerWaalsContact CZ-ND2 3.31Å; F160-N164 WeakPolarHBondContact CZ-ND2 3.16Å; F160-N164 VanDerWaalsContact O-CB 3.28Å; F160-N164 WeakPolarHBondContact O-CB 3.29Å; F160-N164 PolarHBondContact O-N 3.41Å; F160-N164 VanDerWaalsContact O-N 3.17Å; F160-N164 PolarHBondContact O-ND2 3.46Å; N164-F166 PolarHBondContact O-N 2.82Å; N164-F166 VanDerWaalsContact O-N 3.1Å; N164-F167 HydrophobicContact CB-CB 4.06Å; N164-F167 HydrophobicContact CB-CD2 3.69Å; N164-F167 HydrophobicContact CB-CG 4.24Å; N164-F167 CarbonylContact O-C 3.55Å; N164-F167 WeakPolarHBondContact O-CA 3.45Å; N164-F167 PolarHBondContact O-N 3.31Å; N164-N168 PolarHBondContact O-N 3.49Å
165	V	43.5	Very low	59.1	Low	110 Å²	110	76.8 Å²	76.8	67%	0.667	38%	0.381	S	S	*	.	G	3₁₀ helix	trans	-51.1	-35.5	177.6	-179	0	0	0	0	112.6	E163 F167 N168	E163-V165 PolarHBondContact O-N 2.91Å; E163-V165 VanDerWaalsContact O-N 3.08Å; V165-F167 VanDerWaalsContact C-N 3.25Å; V165-F167 PolarHBondContact O-N 3.25Å; V165-N168 VanDerWaalsContact O-CB 3.25Å; V165-N168 WeakPolarHBondContact O-CB 3.05Å; V165-N168 PolarHBondContact O-N 2.86Å
166	F	42.9	Very low	60.8	Low	153 Å²	153	75.2 Å²	75.2	67%	0.671	36%	0.362	S	S	*	.	G	3₁₀ helix	trans	-65.9	-25.7	176	-88.4	-78.8	0	0	0	113.9	N164 F171 M172	N164-F166 PolarHBondContact O-N 2.82Å; N164-F166 VanDerWaalsContact O-N 3.1Å; F166-F171 HydrophobicContact CD1-CE1 4.25Å; F166-M172 WeakPolarHBondContact O-CE 3.36Å
167	F	53.1	Low	62.2	Low	76 Å²	76	72.3 Å²	72.3	33%	0.333	35%	0.346	S	S	.	.	G	3₁₀ helix	trans	-97.2	7.3	178.6	-67.4	-94.9	0	0	0	112.1	I144 F160 N164 V165 C169	I144-F167 HydrophobicContact CB-CD1 3.99Å; I144-F167 HydrophobicContact CB-CE1 4.03Å; I144-F167 HydrophobicContact CD1-CD1 3.52Å; I144-F167 HydrophobicContact CD1-CE1 3.18Å; I144-F167 HydrophobicContact CD1-CZ 4.29Å; I144-F167 HydrophobicContact CG1-CD1 4.06Å; I144-F167 HydrophobicContact CG1-CE1 3.64Å; I144-F167 HydrophobicContact CG2-CD1 3.3Å; I144-F167 HydrophobicContact CG2-CE1 3.45Å; I144-F167 VanDerWaalsContact CG2-CE1 3.45Å; F160-F167 HydrophobicContact CE1-CB 4.2Å; F160-F167 HydrophobicContact CE1-CD1 4.23Å; F160-F167 HydrophobicContact CE1-CD2 4.4Å; F160-F167 HydrophobicContact CE1-CG 4.02Å; F160-F167 HydrophobicContact CZ-CD2 4.43Å; F160-F167 HydrophobicContact CZ-CE2 4.43Å; F160-F167 HydrophobicContact CZ-CG 4.4Å; F160-F167 HydrophobicContact CZ-CZ 4.47Å; N164-F167 HydrophobicContact CB-CB 4.06Å; N164-F167 HydrophobicContact CB-CD2 3.69Å; N164-F167 HydrophobicContact CB-CG 4.24Å; N164-F167 CarbonylContact O-C 3.55Å; N164-F167 WeakPolarHBondContact O-CA 3.45Å; N164-F167 PolarHBondContact O-N 3.31Å; V165-F167 VanDerWaalsContact C-N 3.25Å; V165-F167 PolarHBondContact O-N 3.25Å; F167-C169 PolarHBondContact O-N 3.04Å; F167-C169 VanDerWaalsContact O-N 3.07Å
168	N	63.9	Low	64	Low	66 Å²	66	72.7 Å²	72.7	35%	0.353	35%	0.345	S	S	.	.			trans	-65	114.7	170.6	-166.2	-24	0	0	0	108	N164 V165 R170 F171 M172	N164-N168 PolarHBondContact O-N 3.49Å; V165-N168 VanDerWaalsContact O-CB 3.25Å; V165-N168 WeakPolarHBondContact O-CB 3.05Å; V165-N168 PolarHBondContact O-N 2.86Å; N168-R170 PolarHBondContact O-N 3.35Å; N168-R170 WeakPolarHBondContact OD1-CB 3.14Å; N168-R170 WeakPolarHBondContact OD1-CG 3.38Å; N168-R170 PolarHBondContact OD1-N 3.5Å; N168-R170 VanDerWaalsContact OD1-N 3.16Å; N168-F171 WeakPolarHBondContact O-CB 3.46Å; N168-F171 PolarHBondContact O-N 3.23Å; N168-M172 PolarHBondContact O-N 2.86Å
169	C	65.6	Low	66.1	Low	39 Å²	39	69.8 Å²	69.8	26%	0.264	33%	0.327	S	S	.	.	H	α-helix	trans	-45.7	-33.8	175.4	-77.8	0	0	0	0	113.6	F167 F171 M172 D173 C360	F167-C169 PolarHBondContact O-N 3.04Å; F167-C169 VanDerWaalsContact O-N 3.07Å; C169-F171 PolarHBondContact O-N 2.94Å; C169-M172 PolarHBondContact O-N 3.01Å; C169-D173 VanDerWaalsContact O-CB 3.27Å; C169-D173 WeakPolarHBondContact O-CB 3.21Å; C169-D173 PolarHBondContact O-N 3.01Å; C169-C360 WeakPolarHBondContact CA-SG 2.93Å; C169-C360 HydrophobicContact CB-CB 3.94Å; C169-C360 WeakPolarHBondContact CB-O 3.47Å; C169-C360 WeakPolarHBondContact CB-SG 3.17Å; C169-C360 WeakPolarHBondContact SG-CA 3.3Å; C169-C360 WeakPolarHBondContact SG-CB 3.42Å; C169-C360 PolarHBondContact SG-O 2.84Å; C169-C360 CovalentContact SG-SG 2.05Å; C169-C360 PolarHBondContact SG-SG 3.31Å
170	R	67.6	Low	68	Low	123 Å²	123	64.4 Å²	64.4	46%	0.464	31%	0.307	S	S	.	.	H	α-helix	trans	-58.3	-42.4	173.4	-69.4	174.3	-177.7	-168.5	4	113.5	N168 L174 L363	N168-R170 PolarHBondContact O-N 3.35Å; N168-R170 WeakPolarHBondContact OD1-CB 3.14Å; N168-R170 WeakPolarHBondContact OD1-CG 3.38Å; N168-R170 PolarHBondContact OD1-N 3.5Å; N168-R170 VanDerWaalsContact OD1-N 3.16Å; R170-L174 WeakPolarHBondContact O-CB 3.34Å; R170-L174 PolarHBondContact O-N 2.92Å; R170-L363 HydrophobicContact CB-CD1 4.33Å; R170-L363 HydrophobicContact CG-CD1 3.34Å
171	F	74.9	Confident	70	Confident	83 Å²	83	62.5 Å²	62.5	36%	0.364	30%	0.299	S	S	.	.	H	α-helix	trans	-71.1	-42.5	-179.8	178.9	-102.5	0	0	0	111.2	F166 N168 C169 D173 L174 L175	F166-F171 HydrophobicContact CD1-CE1 4.25Å; N168-F171 WeakPolarHBondContact O-CB 3.46Å; N168-F171 PolarHBondContact O-N 3.23Å; C169-F171 PolarHBondContact O-N 2.94Å; F171-D173 VanDerWaalsContact C-N 3.28Å; F171-D173 PolarHBondContact O-N 2.98Å; F171-L174 PolarHBondContact O-N 3.41Å; F171-L175 HydrophobicContact CE1-CD2 4.24Å; F171-L175 VanDerWaalsContact O-CB 3.28Å; F171-L175 WeakPolarHBondContact O-CB 3.18Å; F171-L175 PolarHBondContact O-N 2.94Å
172	M	76.4	Confident	72.1	Confident	25 Å²	25	58.8 Å²	58.8	12%	0.123	28%	0.276	C	S	.	.	H	α-helix	trans	-62.5	-38.7	175.4	-70.5	-63.7	-179.1	0	0	111.7	V137 F140 F166 N168 C169 L175 T176	V137-M172 HydrophobicContact CG1-SD 3.95Å; F140-M172 HydrophobicContact CB-CE 4.26Å; F166-M172 WeakPolarHBondContact O-CE 3.36Å; N168-M172 PolarHBondContact O-N 2.86Å; C169-M172 PolarHBondContact O-N 3.01Å; M172-L175 PolarHBondContact O-N 3.4Å; M172-T176 WeakPolarHBondContact O-CB 3.32Å; M172-T176 PolarHBondContact O-N 3.45Å; M172-T176 PolarHBondContact O-OG1 3.41Å
173	D	75	Confident	74.2	Confident	9 Å²	9	50.6 Å²	50.6	5%	0.048	25%	0.245	C	C	.	.	H	α-helix	trans	-67.7	-46.6	177.4	-166.9	18.7	0	0	0	112.3	C169 F171 L175 T176 H177 N362 L363	C169-D173 VanDerWaalsContact O-CB 3.27Å; C169-D173 WeakPolarHBondContact O-CB 3.21Å; C169-D173 PolarHBondContact O-N 3.01Å; F171-D173 VanDerWaalsContact C-N 3.28Å; F171-D173 PolarHBondContact O-N 2.98Å; D173-L175 VanDerWaalsContact C-N 3.28Å; D173-L175 PolarHBondContact O-N 2.99Å; D173-T176 PolarHBondContact O-N 2.71Å; D173-H177 PolarHBondContact O-N 3.14Å; D173-H177 PolarHBondContact O-ND1 2.89Å; D173-H177 IonicContact OD1-CE1 3.49Å; D173-H177 PolarHBondContact OD1-CE1 3.3Å; D173-H177 IonicContact OD1-ND1 2.87Å; D173-H177 PolarHBondContact OD1-ND1 3.19Å; D173-N362 PolarHBondContact OD1-OD1 3.12Å; D173-N362 PolarHBondContact OD2-OD1 3.49Å; D173-L363 PolarHBondContact OD2-N 2.94Å
174	L	79	Confident	76.1	Confident	51 Å²	51	45.4 Å²	45.4	27%	0.267	22%	0.221	S	C	.	.	H	α-helix	trans	-52.4	-48.8	171	-180	146.4	0	0	0	111	R170 F171 H177 Y178 I339	R170-L174 WeakPolarHBondContact O-CB 3.34Å; R170-L174 PolarHBondContact O-N 2.92Å; F171-L174 PolarHBondContact O-N 3.41Å; L174-H177 PolarHBondContact O-N 2.94Å; L174-Y178 WeakPolarHBondContact O-CB 3.46Å; L174-Y178 PolarHBondContact O-N 2.99Å; L174-I339 HydrophobicContact CB-CD1 3.46Å; L174-I339 VanDerWaalsContact CB-CD1 3.46Å; L174-I339 HydrophobicContact CD1-CD1 3.24Å; L174-I339 HydrophobicContact CG-CD1 3.58Å
175	L	86.5	Confident	78.1	Confident	45 Å²	45	43.5 Å²	43.5	24%	0.236	21%	0.211	C	C	.	.	H	α-helix	trans	-68.4	-38.7	-176	-172.7	61.2	0	0	0	111.4	V137 F171 M172 D173 Y178 L179	V137-L175 HydrophobicContact CB-CD2 4.47Å; V137-L175 HydrophobicContact CG1-CB 4.25Å; V137-L175 HydrophobicContact CG1-CD2 4.14Å; V137-L175 HydrophobicContact CG1-CG 4.24Å; V137-L175 HydrophobicContact CG2-CD2 3.43Å; V137-L175 VanDerWaalsContact CG2-CD2 3.43Å; V137-L175 HydrophobicContact CG2-CG 3.88Å; F171-L175 HydrophobicContact CE1-CD2 4.24Å; F171-L175 VanDerWaalsContact O-CB 3.28Å; F171-L175 WeakPolarHBondContact O-CB 3.18Å; F171-L175 PolarHBondContact O-N 2.94Å; M172-L175 PolarHBondContact O-N 3.4Å; D173-L175 VanDerWaalsContact C-N 3.28Å; D173-L175 PolarHBondContact O-N 2.99Å; L175-Y178 HydrophobicContact CD1-CD1 4.33Å; L175-Y178 PolarHBondContact O-N 3.37Å; L175-L179 HydrophobicContact CD1-CD1 4.22Å; L175-L179 HydrophobicContact CD1-CG 4.33Å; L175-L179 HydrophobicContact CG-CD1 3.98Å; L175-L179 WeakPolarHBondContact O-CB 3.43Å; L175-L179 WeakPolarHBondContact O-CD1 3.4Å; L175-L179 WeakPolarHBondContact O-CG 3.4Å; L175-L179 PolarHBondContact O-N 2.72Å
176	T	85.5	Confident	80.5	Confident	14 Å²	14	38.3 Å²	38.3	9%	0.086	18%	0.179	C	C	.	.	H	α-helix	trans	-61.5	-51.9	175.7	-58.3	0	0	0	0	110.7	V137 L138 M172 D173 Y178 L179 I180	V137-T176 VanDerWaalsContact CG1-OG1 3.31Å; V137-T176 WeakPolarHBondContact CG1-OG1 3.5Å; L138-T176 HydrophobicContact CD2-CG2 3.67Å; L138-T176 HydrophobicContact CG-CG2 4.22Å; M172-T176 WeakPolarHBondContact O-CB 3.32Å; M172-T176 PolarHBondContact O-N 3.45Å; M172-T176 PolarHBondContact O-OG1 3.41Å; D173-T176 PolarHBondContact O-N 2.71Å; T176-Y178 VanDerWaalsContact C-N 3.35Å; T176-Y178 PolarHBondContact O-N 3.13Å; T176-L179 PolarHBondContact O-N 2.89Å; T176-I180 PolarHBondContact O-N 2.9Å
177	H	84.1	Confident	82.9	Confident	20 Å²	20	31 Å²	31	9%	0.093	15%	0.147	C	C	.	.	H	α-helix	trans	-64.8	-38	179.2	-75.2	94	0	0	0	112.6	D173 L174 I180 L181 T335	D173-H177 PolarHBondContact O-N 3.14Å; D173-H177 PolarHBondContact O-ND1 2.89Å; D173-H177 IonicContact OD1-CE1 3.49Å; D173-H177 PolarHBondContact OD1-CE1 3.3Å; D173-H177 IonicContact OD1-ND1 2.87Å; D173-H177 PolarHBondContact OD1-ND1 3.19Å; L174-H177 PolarHBondContact O-N 2.94Å; H177-I180 VanDerWaalsContact O-CG2 3.3Å; H177-I180 WeakPolarHBondContact O-CG2 3.29Å; H177-L181 WeakPolarHBondContact O-CB 3.44Å; H177-L181 WeakPolarHBondContact O-CG 3.38Å; H177-L181 PolarHBondContact O-N 3.38Å; H177-L181 VanDerWaalsContact O-N 3.12Å; H177-T335 HydrophobicContact CB-CG2 3.96Å
178	Y	89.7	Confident	84.8	Confident	43 Å²	43	29.6 Å²	29.6	17%	0.169	14%	0.141	C	C	.	.	H	α-helix	trans	-61.3	-49.4	174.5	167.6	-93.3	0	0	0	111.4	L174 L175 T176 L181 S182 V328 P331 I332	L174-Y178 WeakPolarHBondContact O-CB 3.46Å; L174-Y178 PolarHBondContact O-N 2.99Å; L175-Y178 HydrophobicContact CD1-CD1 4.33Å; L175-Y178 PolarHBondContact O-N 3.37Å; T176-Y178 VanDerWaalsContact C-N 3.35Å; T176-Y178 PolarHBondContact O-N 3.13Å; Y178-L181 PolarHBondContact O-N 3.43Å; Y178-S182 WeakPolarHBondContact O-CB 3.18Å; Y178-S182 PolarHBondContact O-N 2.99Å; Y178-S182 PolarHBondContact O-OG 3.41Å; Y178-V328 VanDerWaalsContact CE2-O 3.25Å; Y178-V328 WeakPolarHBondContact CE2-O 3.41Å; Y178-V328 WeakPolarHBondContact OH-CG1 3.38Å; Y178-V328 PolarHBondContact OH-O 3.42Å; Y178-V328 VanDerWaalsContact OH-O 3.12Å; Y178-P331 HydrophobicContact CD2-CB 3.73Å; Y178-P331 HydrophobicContact CE2-CB 4Å; Y178-I332 HydrophobicContact CD2-CG1 4.24Å; Y178-I332 HydrophobicContact CE2-CG1 3.86Å
179	L	92.8	Very high	86.2	Confident	4 Å²	4	27.8 Å²	27.8	2%	0.021	13%	0.13	C	C	.	.	H	α-helix	trans	-64.7	-44.3	-178.1	-72	168	0	0	0	111.2	F130 L133 H134 V137 L175 T176 L181 S182 I183	F130-L179 HydrophobicContact CB-CD2 4.32Å; F130-L179 HydrophobicContact CD1-CD2 4.12Å; F130-L179 HydrophobicContact CG-CD2 4.28Å; L133-L179 HydrophobicContact CB-CD1 3.92Å; L133-L179 HydrophobicContact CB-CD2 4.09Å; L133-L179 HydrophobicContact CD1-CD2 4.33Å; H134-L179 HydrophobicContact CB-CB 4.02Å; H134-L179 HydrophobicContact CB-CD1 4.32Å; V137-L179 HydrophobicContact CB-CD1 4.47Å; V137-L179 HydrophobicContact CG2-CD1 3.9Å; L175-L179 HydrophobicContact CD1-CD1 4.22Å; L175-L179 HydrophobicContact CD1-CG 4.33Å; L175-L179 HydrophobicContact CG-CD1 3.98Å; L175-L179 WeakPolarHBondContact O-CB 3.43Å; L175-L179 WeakPolarHBondContact O-CD1 3.4Å; L175-L179 WeakPolarHBondContact O-CG 3.4Å; L175-L179 PolarHBondContact O-N 2.72Å; T176-L179 PolarHBondContact O-N 2.89Å; L179-L181 PolarHBondContact O-N 3.29Å; L179-S182 WeakPolarHBondContact O-CB 3.49Å; L179-S182 PolarHBondContact O-N 2.87Å; L179-I183 WeakPolarHBondContact O-CD1 3.42Å; L179-I183 VanDerWaalsContact O-CG1 3.28Å; L179-I183 WeakPolarHBondContact O-CG1 3.46Å; L179-I183 PolarHBondContact O-N 3.31Å
180	I	90.8	Very high	87.4	Confident	26 Å²	26	26 Å²	26	13%	0.133	12%	0.118	C	C	.	.	H	α-helix	trans	-64.9	-42.1	-179.5	-165.3	60.7	0	0	0	112	T176 H177 S182 I183 Y184 L378	T176-I180 PolarHBondContact O-N 2.9Å; H177-I180 VanDerWaalsContact O-CG2 3.3Å; H177-I180 WeakPolarHBondContact O-CG2 3.29Å; I180-S182 VanDerWaalsContact C-N 3.31Å; I180-S182 PolarHBondContact O-N 2.95Å; I180-I183 HydrophobicContact CD1-CD1 4.22Å; I180-I183 WeakPolarHBondContact O-CB 3.4Å; I180-I183 PolarHBondContact O-N 2.88Å; I180-Y184 HydrophobicContact CD1-CD2 4.09Å; I180-Y184 HydrophobicContact CD1-CE2 3.85Å; I180-Y184 HydrophobicContact CG1-CD2 4.1Å; I180-Y184 HydrophobicContact CG1-CE2 4.02Å; I180-Y184 WeakPolarHBondContact O-CD2 3.31Å; I180-Y184 PolarHBondContact O-N 2.96Å; I180-Y184 VanDerWaalsContact O-N 3.08Å; I180-L378 HydrophobicContact CG1-CD1 4.36Å; I180-L378 HydrophobicContact CG1-CD2 4.12Å; I180-L378 HydrophobicContact CG2-CD2 4.32Å
181	L	91.4	Very high	88.5	Confident	6 Å²	6	20.1 Å²	20.1	3%	0.031	10%	0.096	C	C	.	.	H	α-helix	trans	-63.2	-39.4	174.1	-77	167.1	0	0	0	111.7	H177 Y178 L179 I183 Y184 L185 P331 P334 T335 P377 L378 L381	H177-L181 WeakPolarHBondContact O-CB 3.44Å; H177-L181 WeakPolarHBondContact O-CG 3.38Å; H177-L181 PolarHBondContact O-N 3.38Å; H177-L181 VanDerWaalsContact O-N 3.12Å; Y178-L181 PolarHBondContact O-N 3.43Å; L179-L181 PolarHBondContact O-N 3.29Å; L181-I183 VanDerWaalsContact C-N 3.32Å; L181-I183 PolarHBondContact O-N 3.48Å; L181-Y184 PolarHBondContact O-N 2.88Å; L181-L185 WeakPolarHBondContact O-CB 3.27Å; L181-L185 WeakPolarHBondContact O-CG 3.29Å; L181-L185 PolarHBondContact O-N 3.45Å; L181-P331 HydrophobicContact CB-CB 3.88Å; L181-P331 HydrophobicContact CB-CG 4.17Å; L181-P334 HydrophobicContact CD1-CB 4.29Å; L181-P334 HydrophobicContact CD1-CG 3.73Å; L181-T335 HydrophobicContact CD1-CG2 3.83Å; L181-P377 HydrophobicContact CD2-CB 4.09Å; L181-L378 HydrophobicContact CD2-CB 4.49Å; L181-L378 HydrophobicContact CD2-CD1 4.15Å; L181-L381 HydrophobicContact CD2-CD1 4.36Å
182	S	94.5	Very high	89.2	Confident	0 Å²	0	19 Å²	19	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-61.1	-41.2	175.4	-53.3	0	0	0	0	111.7	F130 Y178 L179 I180 G186 P331	F130-S182 VanDerWaalsContact CD2-CB 3.48Å; Y178-S182 WeakPolarHBondContact O-CB 3.18Å; Y178-S182 PolarHBondContact O-N 2.99Å; Y178-S182 PolarHBondContact O-OG 3.41Å; L179-S182 WeakPolarHBondContact O-CB 3.49Å; L179-S182 PolarHBondContact O-N 2.87Å; I180-S182 VanDerWaalsContact C-N 3.31Å; I180-S182 PolarHBondContact O-N 2.95Å; S182-G186 PolarHBondContact O-N 3.31Å; S182-P331 WeakPolarHBondContact OG-CG 3.49Å
183	I	94.3	Very high	89.6	Confident	0 Å²	0	19.7 Å²	19.7	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-60.9	-50.6	176.5	-70.6	154	0	0	0	110.6	I127 F130 N131 H134 L179 I180 L181 L185 G186 I187	I127-I183 HydrophobicContact CG2-CG2 4.23Å; F130-I183 HydrophobicContact CB-CD1 4.26Å; F130-I183 HydrophobicContact CB-CG1 3.68Å; N131-I183 WeakPolarHBondContact OD1-CD1 3.34Å; N131-I183 VanDerWaalsContact OD1-CG1 3.3Å; N131-I183 WeakPolarHBondContact OD1-CG1 3.46Å; N131-I183 WeakPolarHBondContact OD1-CG2 3.41Å; H134-I183 HydrophobicContact CB-CD1 4.01Å; L179-I183 WeakPolarHBondContact O-CD1 3.42Å; L179-I183 VanDerWaalsContact O-CG1 3.28Å; L179-I183 WeakPolarHBondContact O-CG1 3.46Å; L179-I183 PolarHBondContact O-N 3.31Å; I180-I183 HydrophobicContact CD1-CD1 4.22Å; I180-I183 WeakPolarHBondContact O-CB 3.4Å; I180-I183 PolarHBondContact O-N 2.88Å; L181-I183 VanDerWaalsContact C-N 3.32Å; L181-I183 PolarHBondContact O-N 3.48Å; I183-L185 PolarHBondContact O-N 3.17Å; I183-G186 WeakPolarHBondContact O-CA 3.1Å; I183-G186 PolarHBondContact O-N 3.49Å; I183-G186 VanDerWaalsContact O-N 3.14Å; I183-I187 HydrophobicContact CG2-CD1 4.01Å; I183-I187 WeakPolarHBondContact O-CG1 3.46Å; I183-I187 PolarHBondContact O-N 2.98Å
184	Y	93.9	Very high	90	Very high	2 Å²	2	20 Å²	20	1%	0.008	10%	0.095	C	C	.	.	H	α-helix	trans	-65.8	-38.6	-179.4	-87.8	-92.5	0	0	0	113.1	I180 L181 G186 I187 F188 L378 L381 C382 H427 T428 W431	I180-Y184 HydrophobicContact CD1-CD2 4.09Å; I180-Y184 HydrophobicContact CD1-CE2 3.85Å; I180-Y184 HydrophobicContact CG1-CD2 4.1Å; I180-Y184 HydrophobicContact CG1-CE2 4.02Å; I180-Y184 WeakPolarHBondContact O-CD2 3.31Å; I180-Y184 PolarHBondContact O-N 2.96Å; I180-Y184 VanDerWaalsContact O-N 3.08Å; L181-Y184 PolarHBondContact O-N 2.88Å; Y184-G186 VanDerWaalsContact C-N 3.32Å; Y184-I187 PolarHBondContact O-N 3.44Å; Y184-F188 WeakPolarHBondContact O-CB 3.34Å; Y184-F188 PolarHBondContact O-N 3.32Å; Y184-L378 HydrophobicContact CD1-CD1 4.15Å; Y184-L378 HydrophobicContact CD2-CD1 3.16Å; Y184-L378 HydrophobicContact CD2-CG 4.21Å; Y184-L378 HydrophobicContact CE1-CD1 4.47Å; Y184-L378 HydrophobicContact CE2-CD1 3.53Å; Y184-L378 HydrophobicContact CE2-CD2 4.47Å; Y184-L378 HydrophobicContact CE2-CG 4.12Å; Y184-L378 HydrophobicContact CG-CD1 3.47Å; Y184-L378 VanDerWaalsContact CG-CD1 3.47Å; Y184-L381 HydrophobicContact CD1-CB 4.38Å; Y184-C382 HydrophobicContact CD1-CB 4.36Å; Y184-C382 HydrophobicContact CE1-CB 3.82Å; Y184-H427 HydrophobicContact CE1-CB 4.38Å; Y184-H427 HydrophobicContact CE2-CB 4.18Å; Y184-H427 PolarHBondContact OH-O 3.27Å; Y184-T428 PolarHBondContact OH-N 3.31Å; Y184-W431 WeakPolarHBondContact OH-CB 3.4Å
185	L	94	Very high	90.3	Very high	19 Å²	19	20.8 Å²	20.8	10%	0.099	10%	0.095	C	C	.	.	H	α-helix	trans	-62.3	-41.2	170.8	-75.7	176.7	0	0	0	111.6	L181 I183 I187 F188 F189 I327 L330 P331 L381	L181-L185 WeakPolarHBondContact O-CB 3.27Å; L181-L185 WeakPolarHBondContact O-CG 3.29Å; L181-L185 PolarHBondContact O-N 3.45Å; I183-L185 PolarHBondContact O-N 3.17Å; L185-I187 VanDerWaalsContact C-N 3.34Å; L185-I187 PolarHBondContact O-N 3.19Å; L185-F188 PolarHBondContact O-N 2.88Å; L185-F189 HydrophobicContact CB-CD2 4.32Å; L185-F189 HydrophobicContact CB-CE2 4.33Å; L185-F189 HydrophobicContact CD2-CE2 4.17Å; L185-F189 WeakPolarHBondContact O-CB 3.46Å; L185-F189 WeakPolarHBondContact O-CD2 3.45Å; L185-F189 PolarHBondContact O-N 3.32Å; L185-I327 HydrophobicContact CB-CG1 4.48Å; L185-L330 HydrophobicContact CD1-CB 3.76Å; L185-L330 HydrophobicContact CD1-CD1 4.39Å; L185-P331 HydrophobicContact CD1-CG 3.57Å; L185-L381 HydrophobicContact CD2-CD1 3.81Å; L185-L381 HydrophobicContact CD2-CD2 3.66Å; L185-L381 HydrophobicContact CD2-CG 4.41Å; L185-L381 HydrophobicContact CG-CD1 3.88Å
186	G	93.7	Very high	90.1	Very high	0 Å²	0	21.3 Å²	21.3	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-59	-44.3	175.2	0	0	0	0	0	112.5	I127 S182 I183 Y184 G190	I127-G186 VanDerWaalsContact CD1-C 3.43Å; S182-G186 PolarHBondContact O-N 3.31Å; I183-G186 WeakPolarHBondContact O-CA 3.1Å; I183-G186 PolarHBondContact O-N 3.49Å; I183-G186 VanDerWaalsContact O-N 3.14Å; Y184-G186 VanDerWaalsContact C-N 3.32Å; G186-G190 PolarHBondContact O-N 3.05Å
187	I	93.9	Very high	89.6	Confident	0 Å²	0	23.6 Å²	23.6	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-61.7	-50.1	175.7	-64.9	164	0	0	0	110	I127 I183 Y184 L185 G190 L191 I423 A424 H427	I127-I187 HydrophobicContact CD1-CG1 3.96Å; I183-I187 HydrophobicContact CG2-CD1 4.01Å; I183-I187 WeakPolarHBondContact O-CG1 3.46Å; I183-I187 PolarHBondContact O-N 2.98Å; Y184-I187 PolarHBondContact O-N 3.44Å; L185-I187 VanDerWaalsContact C-N 3.34Å; L185-I187 PolarHBondContact O-N 3.19Å; I187-G190 PolarHBondContact O-N 3.41Å; I187-L191 HydrophobicContact CG2-CD1 3.94Å; I187-L191 WeakPolarHBondContact O-CG 3.45Å; I187-L191 PolarHBondContact O-N 3.1Å; I187-I423 HydrophobicContact CD1-CG2 3.55Å; I187-I423 HydrophobicContact CG1-CG2 3.73Å; I187-A424 HydrophobicContact CG2-CB 3.75Å; I187-H427 HydrophobicContact CD1-CB 4.33Å
188	F	94.4	Very high	89.1	Confident	46 Å²	46	23.8 Å²	23.8	20%	0.202	11%	0.109	C	C	.	.	H	α-helix	trans	-58	-52.5	-179.9	174	-96.5	0	0	0	111.8	Y184 L185 G190 L191 F192 L381 L388	Y184-F188 WeakPolarHBondContact O-CB 3.34Å; Y184-F188 PolarHBondContact O-N 3.32Å; L185-F188 PolarHBondContact O-N 2.88Å; F188-G190 VanDerWaalsContact C-N 3.32Å; F188-G190 PolarHBondContact O-N 3.39Å; F188-L191 PolarHBondContact O-N 3.49Å; F188-F192 VanDerWaalsContact O-CB 3.31Å; F188-F192 WeakPolarHBondContact O-CB 3.45Å; F188-F192 PolarHBondContact O-N 3.03Å; F188-L381 HydrophobicContact CB-CD2 4.36Å; F188-L381 HydrophobicContact CG-CD2 4.38Å; F188-L388 HydrophobicContact CD2-CD1 3.67Å; F188-L388 HydrophobicContact CE2-CD1 3.53Å; F188-L388 HydrophobicContact CZ-CD1 4.36Å
189	F	92.8	Very high	88.2	Confident	28 Å²	28	24.2 Å²	24.2	12%	0.123	12%	0.115	C	C	.	.	H	α-helix	trans	-65.2	-35	179.5	-75.6	-60.6	0	0	0	112.4	L185 F192 E193 V323 I327 L330	L185-F189 HydrophobicContact CB-CD2 4.32Å; L185-F189 HydrophobicContact CB-CE2 4.33Å; L185-F189 HydrophobicContact CD2-CE2 4.17Å; L185-F189 WeakPolarHBondContact O-CB 3.46Å; L185-F189 WeakPolarHBondContact O-CD2 3.45Å; L185-F189 PolarHBondContact O-N 3.32Å; F189-F192 PolarHBondContact O-N 2.9Å; F189-E193 WeakPolarHBondContact O-CB 3.42Å; F189-E193 PolarHBondContact O-N 2.82Å; F189-V323 HydrophobicContact CB-CG1 3.65Å; F189-V323 HydrophobicContact CD1-CG2 4.37Å; F189-V323 HydrophobicContact CD2-CG1 4.41Å; F189-V323 HydrophobicContact CG-CG1 4.01Å; F189-I327 HydrophobicContact CD2-CD1 4.43Å; F189-I327 HydrophobicContact CD2-CG1 3.74Å; F189-I327 HydrophobicContact CE2-CG1 4.38Å; F189-L330 HydrophobicContact CE2-CD1 4.39Å; F189-L330 HydrophobicContact CZ-CD1 4.3Å
190	G	89.2	Confident	87	Confident	2 Å²	2	29.6 Å²	29.6	2%	0.021	14%	0.14	C	C	.	.	H	α-helix	trans	-63.1	-42.6	173.9	0	0	0	0	0	113.2	G186 I187 F188 H194	G186-G190 PolarHBondContact O-N 3.05Å; I187-G190 PolarHBondContact O-N 3.41Å; F188-G190 VanDerWaalsContact C-N 3.32Å; F188-G190 PolarHBondContact O-N 3.39Å; G190-H194 PolarHBondContact O-N 2.77Å
191	L	91.2	Very high	85.4	Confident	0 Å²	0	32.2 Å²	32.2	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-68.7	-41.7	174.2	-70.6	169.2	0	0	0	111.8	I187 F188 H194 Y195 L388 I389 I392 F417 F420	I187-L191 HydrophobicContact CG2-CD1 3.94Å; I187-L191 WeakPolarHBondContact O-CG 3.45Å; I187-L191 PolarHBondContact O-N 3.1Å; F188-L191 PolarHBondContact O-N 3.49Å; L191-H194 WeakPolarHBondContact O-CB 3.3Å; L191-H194 PolarHBondContact O-N 2.99Å; L191-Y195 PolarHBondContact O-N 2.93Å; L191-L388 HydrophobicContact CB-CB 4.28Å; L191-L388 HydrophobicContact CB-CD1 4.17Å; L191-I389 HydrophobicContact CD1-CD1 4.04Å; L191-I389 HydrophobicContact CD1-CG1 3.78Å; L191-I389 HydrophobicContact CD2-CG1 3.79Å; L191-I389 HydrophobicContact CG-CG1 4.46Å; L191-I392 HydrophobicContact CD2-CD1 4.37Å; L191-I392 WeakPolarHBondContact O-CD1 3.22Å; L191-F417 HydrophobicContact CD2-CD2 4.06Å; L191-F417 HydrophobicContact CD2-CE2 4.05Å; L191-F420 HydrophobicContact CD2-CB 3.73Å; L191-F420 HydrophobicContact CG-CB 4.13Å
192	F	90.4	Very high	83.5	Confident	59 Å²	59	34.8 Å²	34.8	26%	0.259	17%	0.169	S	C	.	.	H	α-helix	trans	-64.7	-41	178.9	-174.7	-105.7	0	0	0	112.1	F188 F189 H194 Y195 L196 W319 L388	F188-F192 VanDerWaalsContact O-CB 3.31Å; F188-F192 WeakPolarHBondContact O-CB 3.45Å; F188-F192 PolarHBondContact O-N 3.03Å; F189-F192 PolarHBondContact O-N 2.9Å; F192-H194 VanDerWaalsContact C-N 3.29Å; F192-H194 PolarHBondContact O-N 3.34Å; F192-Y195 WeakPolarHBondContact O-CB 3.37Å; F192-Y195 PolarHBondContact O-N 3.49Å; F192-L196 HydrophobicContact CD1-CD1 3.9Å; F192-L196 HydrophobicContact CD1-CG 4.26Å; F192-L196 HydrophobicContact CE1-CD1 3.49Å; F192-L196 VanDerWaalsContact CE1-CD1 3.49Å; F192-L196 HydrophobicContact CE1-CD2 4.34Å; F192-L196 HydrophobicContact CE1-CG 3.91Å; F192-L196 HydrophobicContact CZ-CD1 4.13Å; F192-L196 HydrophobicContact CZ-CD2 4.14Å; F192-L196 HydrophobicContact CZ-CG 4.14Å; F192-L196 WeakPolarHBondContact O-CG 3.25Å; F192-L196 PolarHBondContact O-N 3.36Å; F192-W319 HydrophobicContact CD1-CH2 4.26Å; F192-W319 AromaticContact CD1-CZ2 3.94Å; F192-W319 HydrophobicContact CD1-CZ2 3.94Å; F192-W319 AromaticContact CE1-CH2 3.91Å; F192-W319 HydrophobicContact CE1-CH2 3.91Å; F192-W319 AromaticContact CE1-CZ2 3.99Å; F192-W319 HydrophobicContact CE1-CZ2 3.99Å; F192-L388 HydrophobicContact CB-CD1 4.36Å
193	E	85.3	Confident	81.2	Confident	40 Å²	40	42.6 Å²	42.6	19%	0.187	20%	0.203	C	C	.	.	H	α-helix	trans	-57.7	-44.2	172.7	-169.9	-167.3	158.5	0	0	110.8	F189 Y195 L196 Q197	F189-E193 WeakPolarHBondContact O-CB 3.42Å; F189-E193 PolarHBondContact O-N 2.82Å; E193-Y195 PolarHBondContact O-N 3.41Å; E193-L196 PolarHBondContact O-N 3.3Å; E193-Q197 WeakPolarHBondContact O-CG 3.35Å; E193-Q197 PolarHBondContact O-N 2.92Å; E193-Q197 PolarHBondContact OE1-NE2 2.93Å
194	H	83.4	Confident	78.6	Confident	15 Å²	15	48.3 Å²	48.3	7%	0.069	23%	0.23	C	C	.	.	H	α-helix	trans	-63.2	-42.5	176.8	-170.1	83.9	0	0	0	112.2	G190 L191 F192 L196 Q197 L198 I392 V413 F417	G190-H194 PolarHBondContact O-N 2.77Å; L191-H194 WeakPolarHBondContact O-CB 3.3Å; L191-H194 PolarHBondContact O-N 2.99Å; F192-H194 VanDerWaalsContact C-N 3.29Å; F192-H194 PolarHBondContact O-N 3.34Å; H194-L196 VanDerWaalsContact C-N 3.34Å; H194-L196 PolarHBondContact O-N 3.26Å; H194-Q197 PolarHBondContact O-N 2.96Å; H194-L198 WeakPolarHBondContact O-CG 3.27Å; H194-L198 PolarHBondContact O-N 3.21Å; H194-I392 HydrophobicContact CB-CD1 4.46Å; H194-V413 WeakPolarHBondContact CE1-CG1 3.26Å; H194-V413 PolarHBondContact CE1-O 2.94Å; H194-F417 AromaticContact CD2-CD2 3.87Å; H194-F417 AromaticContact NE2-CG 3.87Å
195	Y	84.2	Confident	75.9	Confident	67 Å²	67	52.1 Å²	52.1	26%	0.263	26%	0.256	S	S	.	.	H	α-helix	trans	-60.3	-42.2	175	-179.3	-105.1	0	0	0	112.2	L191 F192 E193 L198 N199 L388 I392	L191-Y195 PolarHBondContact O-N 2.93Å; F192-Y195 WeakPolarHBondContact O-CB 3.37Å; F192-Y195 PolarHBondContact O-N 3.49Å; E193-Y195 PolarHBondContact O-N 3.41Å; Y195-L198 PolarHBondContact O-N 3.21Å; Y195-N199 WeakPolarHBondContact CD1-ND2 3.31Å; Y195-N199 WeakPolarHBondContact CE1-ND2 3.33Å; Y195-N199 PolarHBondContact O-N 3.41Å; Y195-N199 PolarHBondContact O-ND2 3.37Å; Y195-L388 HydrophobicContact CG-CD2 4.48Å; Y195-I392 HydrophobicContact CD2-CG1 4.07Å
196	L	82	Confident	73.1	Confident	56 Å²	56	55.8 Å²	55.8	29%	0.293	28%	0.284	S	S	.	.	H	α-helix	trans	-63.9	-44.2	174.9	-72.5	179	0	0	0	112.3	F192 E193 H194 L198 N199 Q200 W319	F192-L196 HydrophobicContact CD1-CD1 3.9Å; F192-L196 HydrophobicContact CD1-CG 4.26Å; F192-L196 HydrophobicContact CE1-CD1 3.49Å; F192-L196 VanDerWaalsContact CE1-CD1 3.49Å; F192-L196 HydrophobicContact CE1-CD2 4.34Å; F192-L196 HydrophobicContact CE1-CG 3.91Å; F192-L196 HydrophobicContact CZ-CD1 4.13Å; F192-L196 HydrophobicContact CZ-CD2 4.14Å; F192-L196 HydrophobicContact CZ-CG 4.14Å; F192-L196 WeakPolarHBondContact O-CG 3.25Å; F192-L196 PolarHBondContact O-N 3.36Å; E193-L196 PolarHBondContact O-N 3.3Å; H194-L196 VanDerWaalsContact C-N 3.34Å; H194-L196 PolarHBondContact O-N 3.26Å; L196-L198 VanDerWaalsContact C-N 3.33Å; L196-L198 PolarHBondContact O-N 3.28Å; L196-N199 WeakPolarHBondContact O-CB 3.41Å; L196-N199 PolarHBondContact O-N 2.86Å; L196-Q200 WeakPolarHBondContact O-CG 3.34Å; L196-Q200 PolarHBondContact O-N 3.1Å; L196-W319 HydrophobicContact CD1-CH2 4.35Å; L196-W319 HydrophobicContact CD1-CZ2 3.93Å
197	Q	75.8	Confident	70.1	Confident	62 Å²	62	61.4 Å²	61.4	29%	0.29	31%	0.313	S	S	.	.	H	α-helix	trans	-59	-45	176.9	-73.7	175	6.3	0	0	111.1	E193 H194 N199 Q200 C201	E193-Q197 WeakPolarHBondContact O-CG 3.35Å; E193-Q197 PolarHBondContact O-N 2.92Å; E193-Q197 PolarHBondContact OE1-NE2 2.93Å; H194-Q197 PolarHBondContact O-N 2.96Å; Q197-N199 PolarHBondContact O-N 3.2Å; Q197-Q200 PolarHBondContact O-N 3.42Å; Q197-C201 PolarHBondContact O-N 2.83Å; Q197-C201 VanDerWaalsContact O-N 3.1Å; Q197-C201 PolarHBondContact O-SG 3.09Å; Q197-C201 VanDerWaalsContact O-SG 3.38Å
198	L	73.9	Confident	67.1	Low	25 Å²	25	68.2 Å²	68.2	13%	0.131	34%	0.344	C	S	.	.	H	α-helix	trans	-58.5	-49.3	173.8	-73.8	170.7	0	0	0	111.2	H194 Y195 L196 Q200 C201 Y202 I392 K395 T396	H194-L198 WeakPolarHBondContact O-CG 3.27Å; H194-L198 PolarHBondContact O-N 3.21Å; Y195-L198 PolarHBondContact O-N 3.21Å; L196-L198 VanDerWaalsContact C-N 3.33Å; L196-L198 PolarHBondContact O-N 3.28Å; L198-Q200 VanDerWaalsContact C-N 3.29Å; L198-Q200 PolarHBondContact O-N 3.31Å; L198-C201 PolarHBondContact O-N 2.8Å; L198-Y202 HydrophobicContact CB-CE2 4.18Å; L198-Y202 HydrophobicContact CD2-CE2 4.24Å; L198-Y202 WeakPolarHBondContact O-CD2 3.49Å; L198-Y202 WeakPolarHBondContact O-CE2 3.24Å; L198-Y202 PolarHBondContact O-N 2.92Å; L198-I392 HydrophobicContact CD1-CB 4.48Å; L198-I392 HydrophobicContact CD1-CG1 4.4Å; L198-I392 HydrophobicContact CD1-CG2 3.74Å; L198-K395 HydrophobicContact CB-CD 4.5Å; L198-T396 HydrophobicContact CD1-CG2 4.24Å; L198-T396 HydrophobicContact CD2-CG2 4.43Å
199	N	71.2	Confident	64	Low	52 Å²	52	72.8 Å²	72.8	28%	0.278	38%	0.376	S	S	.	.	H	α-helix	trans	-55.3	-40.2	177	-77.9	-35.2	0	0	0	113.5	Y195 L196 Q197 Y202 K203 K395	Y195-N199 WeakPolarHBondContact CD1-ND2 3.31Å; Y195-N199 WeakPolarHBondContact CE1-ND2 3.33Å; Y195-N199 PolarHBondContact O-N 3.41Å; Y195-N199 PolarHBondContact O-ND2 3.37Å; L196-N199 WeakPolarHBondContact O-CB 3.41Å; L196-N199 PolarHBondContact O-N 2.86Å; Q197-N199 PolarHBondContact O-N 3.2Å; N199-Y202 PolarHBondContact O-N 2.8Å; N199-K203 PolarHBondContact O-N 3.42Å; N199-K203 VanDerWaalsContact O-N 3.11Å; N199-K395 PolarHBondContact OD1-NZ 2.77Å
200	Q	66.1	Low	60.8	Low	117 Å²	117	79 Å²	79	55%	0.547	40%	0.403	S	S	.	.	H	α-helix	trans	-69.3	-39.9	179.1	-70.8	179.7	1.8	0	0	112.6	L196 Q197 L198 Y202 K203 H204	L196-Q200 WeakPolarHBondContact O-CG 3.34Å; L196-Q200 PolarHBondContact O-N 3.1Å; Q197-Q200 PolarHBondContact O-N 3.42Å; L198-Q200 VanDerWaalsContact C-N 3.29Å; L198-Q200 PolarHBondContact O-N 3.31Å; Q200-Y202 VanDerWaalsContact C-N 3.28Å; Q200-Y202 PolarHBondContact O-N 3.38Å; Q200-K203 PolarHBondContact O-N 3.34Å; Q200-H204 PolarHBondContact O-N 3.43Å
201	C	57.6	Low	57.9	Low	81 Å²	81	83.8 Å²	83.8	55%	0.547	43%	0.434	S	S	.	.	H	α-helix	trans	-58.7	-40.5	175.9	-69.6	0	0	0	0	111.8	Q197 L198	Q197-C201 PolarHBondContact O-N 2.83Å; Q197-C201 VanDerWaalsContact O-N 3.1Å; Q197-C201 PolarHBondContact O-SG 3.09Å; Q197-C201 VanDerWaalsContact O-SG 3.38Å; L198-C201 PolarHBondContact O-N 2.8Å
202	Y	51.5	Low	54.9	Low	60 Å²	60	95.1 Å²	95.1	24%	0.235	48%	0.477	C	S	.	.	H	α-helix	trans	-78.7	-27.7	-179.9	-61.3	-65.6	0	0	0	114.1	L198 N199 Q200 H204 S205 K395 N399	L198-Y202 HydrophobicContact CB-CE2 4.18Å; L198-Y202 HydrophobicContact CD2-CE2 4.24Å; L198-Y202 WeakPolarHBondContact O-CD2 3.49Å; L198-Y202 WeakPolarHBondContact O-CE2 3.24Å; L198-Y202 PolarHBondContact O-N 2.92Å; N199-Y202 PolarHBondContact O-N 2.8Å; Q200-Y202 VanDerWaalsContact C-N 3.28Å; Q200-Y202 PolarHBondContact O-N 3.38Å; Y202-H204 VanDerWaalsContact C-N 3.26Å; Y202-H204 PolarHBondContact O-N 2.97Å; Y202-S205 PolarHBondContact O-N 3.31Å; Y202-S205 PolarHBondContact O-OG 3.28Å; Y202-K395 HydrophobicContact CD2-CD 4.44Å; Y202-K395 HydrophobicContact CE2-CD 4.18Å; Y202-K395 HydrophobicContact CE2-CG 4.18Å; Y202-N399 HydrophobicContact CE1-CB 3.68Å; Y202-N399 VanDerWaalsContact CZ-ND2 3.31Å; Y202-N399 VanDerWaalsContact OH-CB 3.25Å; Y202-N399 WeakPolarHBondContact OH-CB 3.42Å; Y202-N399 PolarHBondContact OH-ND2 2.8Å
203	K	46.1	Very low	51.9	Low	164 Å²	164	101 Å²	101	71%	0.713	50%	0.502	S	S	*	.	H	α-helix	trans	-66.2	-28.7	173.3	-98.5	-172.8	176.4	-178.1	0	112.8	N199 Q200 S206	N199-K203 PolarHBondContact O-N 3.42Å; N199-K203 VanDerWaalsContact O-N 3.11Å; Q200-K203 PolarHBondContact O-N 3.34Å; K203-S206 PolarHBondContact O-OG 3.15Å
204	H	39.9	Very low	49.1	Very low	120 Å²	120	103.8 Å²	103.8	56%	0.556	53%	0.525	S	S	*	.	H	α-helix	trans	-82.2	-24.6	178.9	-95.5	-61.4	0	0	0	113.5	Q200 Y202 S206	Q200-H204 PolarHBondContact O-N 3.43Å; Y202-H204 VanDerWaalsContact C-N 3.26Å; Y202-H204 PolarHBondContact O-N 2.97Å; H204-S206 VanDerWaalsContact C-N 3.27Å; H204-S206 PolarHBondContact O-N 3.13Å
205	S	37.6	Very low	46.5	Very low	82 Å²	82	112.2 Å²	112.2	57%	0.573	56%	0.562	S	S	*	*	H	α-helix	trans	-74.6	-13.7	177.3	52.9	0	0	0	0	114.1	Y202	Y202-S205 PolarHBondContact O-N 3.31Å; Y202-S205 PolarHBondContact O-OG 3.28Å
206	S	34.5	Very low	43.8	Very low	96 Å²	96	112.6 Å²	112.6	67%	0.671	57%	0.574	S	S	*	*	T	Hydrogen-bonded Turn	trans	-96.8	4.4	179.6	66.7	0	0	0	0	114.6	K203 H204 E208	K203-S206 PolarHBondContact O-OG 3.15Å; H204-S206 VanDerWaalsContact C-N 3.27Å; H204-S206 PolarHBondContact O-N 3.13Å; S206-E208 PolarHBondContact O-N 3.28Å; S206-E208 VanDerWaalsContact O-N 3.17Å
207	I	31.5	Very low	41.3	Very low	118 Å²	118	115.9 Å²	115.9	61%	0.605	60%	0.599	S	S	*	*	S	Bend	trans	-82.2	97.8	173.8	-61.1	176.5	0	0	0	108
208	E	30.3	Very low	39.1	Very low	143 Å²	143	120.5 Å²	120.5	67%	0.668	62%	0.62	S	S	*	*			trans	22.9	99.1	160.9	-65.1	-176.6	169.7	0	0	114.9	S206 K210	S206-E208 PolarHBondContact O-N 3.28Å; S206-E208 VanDerWaalsContact O-N 3.17Å; E208-K210 HydrophobicContact CB-CG 4.39Å; E208-K210 PolarHBondContact O-N 3.3Å; E208-K210 WeakPolarHBondContact OE2-CE 3.49Å
209	T	29	Very low	36.9	Very low	142 Å²	142	125.2 Å²	125.2	87%	0.871	65%	0.654	S	S	*	*			trans	-58.1	83.6	138.1	48.6	0	0	0	0	106.5	P211	T209-P211 WeakPolarHBondContact O-CD 3.4Å
210	K	26.8	Very low	34.9	Very low	157 Å²	157	130.2 Å²	130.2	68%	0.683	68%	0.679	S	S	*	*			trans	-50.8	119.5	153.5	-82.2	-176.6	178	174.8	0	103.4	E208 W212	E208-K210 HydrophobicContact CB-CG 4.39Å; E208-K210 PolarHBondContact O-N 3.3Å; E208-K210 WeakPolarHBondContact OE2-CE 3.49Å; K210-W212 PolarHBondContact O-N 2.97Å
211	P	27	Very low	33.1	Very low	104 Å²	104	137.4 Å²	137.4	68%	0.675	70%	0.702	S	S	*	*			trans	-53.1	119.3	173.4	22.7	-30.2	0	0	0	103.8	T209 K213	T209-P211 WeakPolarHBondContact O-CD 3.4Å; P211-K213 PolarHBondContact O-N 2.86Å
212	W	28.4	Very low	31.9	Very low	237 Å²	237	142.4 Å²	142.4	90%	0.898	71%	0.714	S	S	*	*			trans	-57.2	92.6	159.9	-117.7	45.5	0	0	0	103.1	K210 C214	K210-W212 PolarHBondContact O-N 2.97Å; W212-C214 PolarHBondContact O-N 3.47Å
213	K	26.8	Very low	30.9	Very low	183 Å²	183	149.5 Å²	149.5	80%	0.796	75%	0.746	S	S	*	*			trans	-63.3	76.3	155.6	-79.9	-173.6	176.9	179.5	0	103.3	P211 K215	P211-K213 PolarHBondContact O-N 2.86Å; K213-K215 PolarHBondContact O-N 3.33Å
214	C	27.2	Very low	30.2	Very low	98 Å²	98	151 Å²	151	66%	0.662	76%	0.756	S	S	*	*			trans	-62.7	87.2	158.6	-138.2	0	0	0	0	103	W212 S216	W212-C214 PolarHBondContact O-N 3.47Å; C214-S216 VanDerWaalsContact C-N 3.25Å; C214-S216 PolarHBondContact O-N 2.89Å
215	K	29.2	Very low	29.8	Very low	193 Å²	193	155 Å²	155	84%	0.839	77%	0.771	S	S	*	*			trans	-57.3	102.2	165.2	-83.9	-174.9	174.3	-177.7	0	105.2	K213	K213-K215 PolarHBondContact O-N 3.33Å
216	S	27.9	Very low	29.3	Very low	74 Å²	74	159.7 Å²	159.7	52%	0.517	78%	0.784	S	S	.	*			trans	58.1	124.1	151.9	-167.9	0	0	0	0	117.8	C214 H218	C214-S216 VanDerWaalsContact C-N 3.25Å; C214-S216 PolarHBondContact O-N 2.89Å; S216-H218 PolarHBondContact O-N 2.87Å; S216-H218 WeakPolarHBondContact OG-CB 3.32Å
217	P	28.5	Very low	29.2	Very low	126 Å²	126	161 Å²	161	82%	0.818	79%	0.79	S	S	*	*	S	Bend	trans	-76.5	62	167.8	36	-33	0	0	0	109.9
218	H	30.9	Very low	29.1	Very low	159 Å²	159	159.6 Å²	159.6	74%	0.736	79%	0.791	S	S	*	*			trans	-147.4	31.7	-176.3	-85.8	-67.1	0	0	0	115.6	S216	S216-H218 PolarHBondContact O-N 2.87Å; S216-H218 WeakPolarHBondContact OG-CB 3.32Å
219	C	27.7	Very low	29.2	Very low	124 Å²	124	159 Å²	159	84%	0.838	80%	0.798	S	S	*	*	S	Bend	trans	-148.8	78.3	173.1	-85.3	0	0	0	0	111.6
220	L	28.9	Very low	29.3	Very low	156 Å²	156	157.7 Å²	157.7	82%	0.817	79%	0.794	S	S	*	*			trans	-177.6	46.7	143.7	-95.9	160.6	0	0	0	110.2	K222	L220-K222 PolarHBondContact O-N 2.82Å; L220-K222 VanDerWaalsContact O-N 3.15Å
221	W	28	Very low	29.2	Very low	268 Å²	268	156.6 Å²	156.6	100%	1.015	81%	0.805	S	S	*	*			trans	-78.8	78.2	154.5	-95	52.1	0	0	0	107.7
222	K	32.7	Very low	29.3	Very low	186 Å²	186	160.5 Å²	160.5	81%	0.809	81%	0.814	S	S	*	*			trans	-98.6	100.5	166.7	-127.1	179.1	-176.1	179.5	0	108	L220 Q224	L220-K222 PolarHBondContact O-N 2.82Å; L220-K222 VanDerWaalsContact O-N 3.15Å; K222-Q224 PolarHBondContact O-N 3.46Å
223	K	29.2	Very low	29.4	Very low	209 Å²	209	159.4 Å²	159.4	91%	0.909	82%	0.815	S	S	*	*			trans	-29.8	110.7	168.2	-72.6	172.4	172.5	175.6	0	112
224	Q	31.4	Very low	29.6	Very low	196 Å²	196	157 Å²	157	92%	0.916	82%	0.816	S	S	*	*			trans	-133.7	127.4	151.6	-121.6	175.9	0.9	0	0	108.9	K222	K222-Q224 PolarHBondContact O-N 3.46Å
225	K	32.5	Very low	29.7	Very low	203 Å²	203	161.4 Å²	161.4	88%	0.883	82%	0.824	S	S	*	*			trans	-57.8	138.7	-162.6	-68.4	167.1	170.4	178.4	0	112.7
226	H	27.9	Very low	29.7	Very low	181 Å²	181	163 Å²	163	84%	0.838	83%	0.826	S	S	*	*			trans	-48.6	148.1	160.4	-83.1	-69.7	0	0	0	111.2
227	P	31.9	Very low	29.9	Very low	123 Å²	123	165.6 Å²	165.6	80%	0.799	83%	0.834	S	S	*	*				-120.6	135.6	99.8	-0.6	20.6	0	0	0	112.4
228	S	29	Very low	30	Very low	90 Å²	90	167.3 Å²	167.3	63%	0.629	84%	0.836	S	S	*	*			trans	-33.6	132.8	162.4	49.1	0	0	0	0	115.2
229	T	31.9	Very low	30	Very low	131 Å²	131	169.9 Å²	169.9	80%	0.804	84%	0.84	S	S	*	*				177.9	127.7	115.2	28.2	0	0	0	0	112.6
230	S	31	Very low	30	Very low	113 Å²	113	170.1 Å²	170.1	79%	0.79	83%	0.832	S	S	*	*			trans	52.3	112	152.9	62.9	0	0	0	0	121.5
231	C	25.2	Very low	30.1	Very low	135 Å²	135	169.6 Å²	169.6	91%	0.912	84%	0.835	S	S	*	*			trans	-60.7	129.3	155.4	-66	0	0	0	0	112
232	Q	30	Very low	30	Very low	185 Å²	185	163.8 Å²	163.8	86%	0.864	82%	0.824	S	S	*	*			trans	-125.8	116	155.2	-108.8	-179.9	-12.1	0	0	108.6
233	K	29.4	Very low	29.9	Very low	214 Å²	214	159.2 Å²	159.2	93%	0.93	82%	0.816	S	S	*	*	P	Polyproline II helix	trans	-70.6	122.7	166.3	-80.3	177.3	172.9	177.5	0	108.3
234	V	30.8	Very low	29.9	Very low	134 Å²	134	159.9 Å²	159.9	81%	0.812	81%	0.814	S	S	*	*	P	Polyproline II helix	trans	-100.4	123.2	169.5	177.2	0	0	0	0	108.4
235	K	30	Very low	29.8	Very low	189 Å²	189	154.7 Å²	154.7	82%	0.822	81%	0.805	S	S	*	*	P	Polyproline II helix	trans	-65.5	137.5	174.8	-81.4	176.2	168.5	-178.6	0	111.1
236	Y	30	Very low	29.7	Very low	227 Å²	227	151 Å²	151	89%	0.89	80%	0.799	S	S	*	*	P	Polyproline II helix	trans	-82.6	129.7	157.1	-105.7	-98.3	0	0	0	108.5
237	N	31.3	Very low	30	Very low	129 Å²	129	149.2 Å²	149.2	69%	0.69	80%	0.802	S	S	*	*			trans	-82.4	112.7	172.1	-75.7	-26	0	0	0	108.8
238	D	29.9	Very low	29.9	Very low	161 Å²	161	146.6 Å²	146.6	86%	0.861	80%	0.796	S	S	*	*			trans	-87.5	122.2	159.3	-78.1	-30.8	0	0	0	108.4
239	W	31.4	Very low	29.9	Very low	214 Å²	214	149.5 Å²	149.5	81%	0.811	81%	0.81	S	S	*	*			trans	-95.2	117.6	171.9	-83.6	55.5	0	0	0	109.3
240	L	28.5	Very low	29.8	Very low	129 Å²	129	148.7 Å²	148.7	68%	0.675	81%	0.805	S	S	*	*			trans	52.5	104.2	150.2	-78.6	96.4	0	0	0	119.2
241	T	30	Very low	29.9	Very low	144 Å²	144	152.5 Å²	152.5	88%	0.883	81%	0.808	S	S	*	*			trans	-124	110	133	22.8	0	0	0	0	108.4
242	D	27.1	Very low	30.2	Very low	146 Å²	146	152.2 Å²	152.2	78%	0.781	80%	0.802	S	S	*	*			trans	-68.8	131.2	160.6	-85.6	-38.1	0	0	0	108.4
243	S	29.6	Very low	30.1	Very low	90 Å²	90	149.9 Å²	149.9	63%	0.629	80%	0.795	S	S	*	*				168.8	130.1	102.5	82.2	0	0	0	0	110.8
244	Y	29	Very low	30.2	Very low	223 Å²	223	147.9 Å²	147.9	88%	0.875	79%	0.794	S	S	*	*			trans	59.2	108.6	158	-53.7	-74	0	0	0	119.4
245	A	30.5	Very low	30	Very low	87 Å²	87	147.1 Å²	147.1	72%	0.719	79%	0.789	S	S	*	*				161.4	98.1	101.1	0	0	0	0	0	111.9
246	T	29.5	Very low	30.1	Very low	125 Å²	125	146.7 Å²	146.7	77%	0.767	79%	0.787	S	S	*	*				44.9	131	125.4	26.2	0	0	0	0	122.5
247	T	33.1	Very low	30.2	Very low	145 Å²	145	143.6 Å²	143.6	89%	0.89	78%	0.778	S	S	*	*			trans	82.6	126.8	159.1	71.9	0	0	0	0	115.4
248	G	30.1	Very low	30.1	Very low	67 Å²	67	144.9 Å²	144.9	69%	0.691	78%	0.778	S	S	*	*			cis	167.6	166.3	6.4	0	0	0	0	0	107.4
249	V	30.8	Very low	30	Very low	151 Å²	151	145.2 Å²	145.2	92%	0.915	77%	0.774	S	S	*	*			trans	98.6	127.4	171.5	-164.9	0	0	0	0	116.6
250	T	29	Very low	29.8	Very low	115 Å²	115	139.5 Å²	139.5	71%	0.706	77%	0.766	S	S	*	*			trans	-114.6	172.2	-160.9	37	0	0	0	0	111.9
251	K	32.2	Very low	29.7	Very low	193 Å²	193	139 Å²	139	84%	0.839	77%	0.768	S	S	*	*			trans	88.7	133.8	163.5	-56.5	-176	174.3	177.5	0	114
252	V	31.7	Very low	29.7	Very low	129 Å²	129	138.4 Å²	138.4	78%	0.782	76%	0.758	S	S	*	*			cis	-154.7	147.9	24.5	177.7	0	0	0	0	110.3
253	N	28.6	Very low	29.9	Very low	136 Å²	136	137.2 Å²	137.2	73%	0.727	76%	0.756	S	S	*	*			trans	-27.2	141.8	162.6	-66.7	-42	0	0	0	119.4
254	L	30.8	Very low	30	Very low	172 Å²	172	141.4 Å²	141.4	90%	0.901	77%	0.766	S	S	*	*				-161.3	101.1	124.4	-122.7	125.3	0	0	0	114.3
255	V	27.8	Very low	30.3	Very low	117 Å²	117	135.8 Å²	135.8	71%	0.709	76%	0.757	S	S	*	*			trans	-6.6	130.4	148.6	-166.6	0	0	0	0	118.9
256	K	31.6	Very low	30.6	Very low	181 Å²	181	139.4 Å²	139.4	79%	0.787	76%	0.759	S	S	*	*				173.4	117	114	-95.3	-179.2	-178.1	171.3	0	114.5
257	K	31	Very low	30.9	Very low	162 Å²	162	139.7 Å²	139.7	70%	0.704	76%	0.756	S	S	*	*				59.1	139.7	127.7	-74.6	-178.7	164.2	-166.1	0	119.3
258	F	29.8	Very low	31.1	Very low	155 Å²	155	141 Å²	141	68%	0.68	75%	0.749	S	S	*	*			cis	-170.8	135	5.6	-97.8	-61.6	0	0	0	104.6
259	Q	27.8	Very low	31.3	Very low	168 Å²	168	144.9 Å²	144.9	79%	0.785	75%	0.747	S	S	*	*				49.8	129.3	75.7	-145.6	159.8	13.1	0	0	112.6
260	C	26.5	Very low	31.6	Very low	94 Å²	94	145.6 Å²	145.6	64%	0.635	74%	0.738	S	S	*	*			cis	-174.5	165.6	23.1	-133.9	0	0	0	0	110
261	V	27.8	Very low	32.1	Very low	118 Å²	118	144 Å²	144	72%	0.715	73%	0.728	S	S	*	*			trans	70	141.9	136	170.8	0	0	0	0	118.3
262	I	29.7	Very low	32.5	Very low	133 Å²	133	139.2 Å²	139.2	68%	0.682	72%	0.715	S	S	*	*			cis	170.5	154.8	-17.4	-99.4	163	0	0	0	103.9
263	T	31.6	Very low	32.9	Very low	121 Å²	121	140.4 Å²	140.4	74%	0.742	71%	0.705	S	S	*	*			trans	69.2	107.7	158.9	52.8	0	0	0	0	123.5
264	Q	31	Very low	33.7	Very low	177 Å²	177	136.2 Å²	136.2	83%	0.827	69%	0.687	S	S	*	*				54.1	160.2	129.5	-73	-165.3	-3.4	0	0	121.8
265	P	36.5	Very low	34.3	Very low	106 Å²	106	133.9 Å²	133.9	69%	0.688	67%	0.674	S	S	*	*			cis	-130.3	-176.8	15.6	35.2	-12.6	0	0	0	116.5	D267	P265-D267 PolarHBondContact O-N 2.89Å
266	E	36.1	Very low	35.1	Very low	162 Å²	162	133.7 Å²	133.7	76%	0.757	67%	0.665	S	S	*	*	T	Hydrogen-bonded Turn	trans	-62.7	-4.7	-154.2	-65.3	175.6	132.8	0	0	119.5	K268	E266-K268 PolarHBondContact O-N 2.99Å
267	D	35.7	Very low	35.7	Very low	132 Å²	132	133.4 Å²	133.4	71%	0.706	66%	0.66	S	S	*	*	T	Hydrogen-bonded Turn	trans	-83.2	-15.2	-172.5	-75.4	-38	0	0	0	115.1	P265 F269	P265-D267 PolarHBondContact O-N 2.89Å; D267-F269 VanDerWaalsContact C-N 3.34Å
268	K	36.8	Very low	36.5	Very low	171 Å²	171	130.7 Å²	130.7	74%	0.743	65%	0.652	S	S	*	*	H	α-helix	trans	-81.7	-9.7	175.5	-74.7	-179	177.3	175.5	0	114	E266 V272	E266-K268 PolarHBondContact O-N 2.99Å; K268-V272 WeakPolarHBondContact O-CG2 3.24Å
269	F	35.2	Very low	37.3	Very low	150 Å²	150	130 Å²	130	66%	0.658	65%	0.649	S	S	*	*	H	α-helix	trans	-83.2	-19.4	178.4	-103.7	-84.9	0	0	0	114	D267 R273	D267-F269 VanDerWaalsContact C-N 3.34Å; F269-R273 PolarHBondContact O-N 3.11Å
270	K	36.6	Very low	38.3	Very low	166 Å²	166	128.2 Å²	128.2	72%	0.722	64%	0.638	S	S	*	*	H	α-helix	trans	-78.2	-34.6	174.2	-83.8	178.4	179.3	168.9	0	112.6	S274	K270-S274 PolarHBondContact O-N 3.34Å; K270-S274 PolarHBondContact O-OG 2.84Å
271	T	39.1	Very low	39.3	Very low	80 Å²	80	128 Å²	128	49%	0.491	63%	0.631	S	S	.	*	H	α-helix	trans	-75.8	-31.8	-179.7	7	0	0	0	0	113.1	S274 L275	T271-S274 PolarHBondContact O-OG 3.4Å; T271-L275 PolarHBondContact O-N 3.07Å; T271-L275 VanDerWaalsContact O-N 3.16Å
272	V	41.7	Very low	40.1	Very low	93 Å²	93	128.8 Å²	128.8	56%	0.564	63%	0.626	S	S	*	*	H	α-helix	trans	-74	-37.5	173.3	-179.8	0	0	0	0	111.1	K268 S274 L275 E276	K268-V272 WeakPolarHBondContact O-CG2 3.24Å; V272-S274 PolarHBondContact O-N 3.43Å; V272-L275 PolarHBondContact O-N 3.4Å; V272-E276 WeakPolarHBondContact O-CB 3.46Å; V272-E276 PolarHBondContact O-N 3.39Å
273	R	39.9	Very low	40.8	Very low	155 Å²	155	127.1 Å²	127.1	59%	0.585	62%	0.616	S	S	*	*	H	α-helix	trans	-68.1	-30.1	173.3	-81.5	-174.5	-163.8	164	7.8	113.6	F269 R277	F269-R273 PolarHBondContact O-N 3.11Å; R273-R277 VanDerWaalsContact O-CG 3.31Å; R273-R277 WeakPolarHBondContact O-CG 3.19Å; R273-R277 PolarHBondContact O-N 3.28Å
274	S	45.3	Very low	41.3	Very low	48 Å²	48	129.3 Å²	129.3	34%	0.336	61%	0.61	S	S	.	*	H	α-helix	trans	-75.3	-40.2	175.7	64.7	0	0	0	0	111.8	K270 T271 V272 E276 R277 I278	K270-S274 PolarHBondContact O-N 3.34Å; K270-S274 PolarHBondContact O-OG 2.84Å; T271-S274 PolarHBondContact O-OG 3.4Å; V272-S274 PolarHBondContact O-N 3.43Å; S274-E276 VanDerWaalsContact C-N 3.34Å; S274-E276 PolarHBondContact O-N 3.33Å; S274-R277 PolarHBondContact O-N 3.41Å; S274-I278 WeakPolarHBondContact O-CD1 3.25Å; S274-I278 VanDerWaalsContact O-CG1 3.25Å; S274-I278 WeakPolarHBondContact O-CG1 3.39Å; S274-I278 PolarHBondContact O-N 3.27Å
275	L	42.4	Very low	41.8	Very low	122 Å²	122	128.1 Å²	128.1	64%	0.639	60%	0.603	S	S	*	*	H	α-helix	trans	-64.4	-37.1	173.2	-104.2	103.6	0	0	0	112.6	T271 V272 I278 K279	T271-L275 PolarHBondContact O-N 3.07Å; T271-L275 VanDerWaalsContact O-N 3.16Å; V272-L275 PolarHBondContact O-N 3.4Å; L275-I278 PolarHBondContact O-N 3.32Å; L275-K279 WeakPolarHBondContact O-CB 3.43Å; L275-K279 PolarHBondContact O-N 2.93Å
276	E	45.3	Very low	42	Very low	113 Å²	113	127.3 Å²	127.3	53%	0.528	60%	0.595	S	S	.	*	H	α-helix	trans	-72.2	-29.8	178.5	-154.7	171.4	-156	0	0	112.5	V272 S274 K280	V272-E276 WeakPolarHBondContact O-CB 3.46Å; V272-E276 PolarHBondContact O-N 3.39Å; S274-E276 VanDerWaalsContact C-N 3.34Å; S274-E276 PolarHBondContact O-N 3.33Å; E276-K280 WeakPolarHBondContact O-CB 3.32Å; E276-K280 WeakPolarHBondContact O-CG 3.31Å; E276-K280 PolarHBondContact O-N 3.46Å; E276-K280 VanDerWaalsContact O-N 3.1Å
277	R	44.8	Very low	42.1	Very low	176 Å²	176	128 Å²	128	66%	0.664	59%	0.591	S	S	*	*	H	α-helix	trans	-71.2	-42	169.5	-75.3	178.5	-162.4	171.8	3.5	112.3	R273 S274 K279 K280 D281	R273-R277 VanDerWaalsContact O-CG 3.31Å; R273-R277 WeakPolarHBondContact O-CG 3.19Å; R273-R277 PolarHBondContact O-N 3.28Å; S274-R277 PolarHBondContact O-N 3.41Å; R277-K279 VanDerWaalsContact C-N 3.33Å; R277-K279 PolarHBondContact O-N 3.02Å; R277-K280 PolarHBondContact O-N 3.4Å; R277-D281 PolarHBondContact O-N 3.44Å
278	I	46.5	Very low	42.1	Very low	105 Å²	105	128.6 Å²	128.6	54%	0.538	59%	0.588	S	S	.	*	H	α-helix	trans	-65.8	-37.9	177.7	-66.3	164	0	0	0	110.7	S274 L275 D281 Q282	S274-I278 WeakPolarHBondContact O-CD1 3.25Å; S274-I278 VanDerWaalsContact O-CG1 3.25Å; S274-I278 WeakPolarHBondContact O-CG1 3.39Å; S274-I278 PolarHBondContact O-N 3.27Å; L275-I278 PolarHBondContact O-N 3.32Å; I278-D281 PolarHBondContact O-N 2.86Å; I278-Q282 PolarHBondContact O-N 3.48Å
279	K	47.2	Very low	42.1	Very low	141 Å²	141	125.7 Å²	125.7	61%	0.613	58%	0.584	S	S	*	*	H	α-helix	trans	-67.2	-40.6	174.7	-163.1	177.1	-178.9	-176.9	0	112.4	L275 R277 Q282 E283	L275-K279 WeakPolarHBondContact O-CB 3.43Å; L275-K279 PolarHBondContact O-N 2.93Å; R277-K279 VanDerWaalsContact C-N 3.33Å; R277-K279 PolarHBondContact O-N 3.02Å; K279-Q282 PolarHBondContact O-N 2.95Å; K279-E283 WeakPolarHBondContact O-CB 3.49Å; K279-E283 PolarHBondContact O-N 3.48Å
280	K	49.5	Very low	42.2	Very low	130 Å²	130	123.8 Å²	123.8	57%	0.565	59%	0.585	S	S	*	*	H	α-helix	trans	-67.9	-31.8	174	-80.9	178.9	176.9	172.5	0	113.2	E276 R277 R284	E276-K280 WeakPolarHBondContact O-CB 3.32Å; E276-K280 WeakPolarHBondContact O-CG 3.31Å; E276-K280 PolarHBondContact O-N 3.46Å; E276-K280 VanDerWaalsContact O-N 3.1Å; R277-K280 PolarHBondContact O-N 3.4Å; K280-R284 PolarHBondContact O-N 3.41Å
281	D	46.8	Very low	42.2	Very low	90 Å²	90	119 Å²	119	48%	0.481	57%	0.567	S	S	.	*	H	α-helix	trans	-77.5	-33.3	175	-99.9	-0.5	0	0	0	113.1	R277 I278 R284 K285	R277-D281 PolarHBondContact O-N 3.44Å; I278-D281 PolarHBondContact O-N 2.86Å; D281-R284 PolarHBondContact O-N 2.87Å; D281-K285 WeakPolarHBondContact O-CB 3.39Å; D281-K285 WeakPolarHBondContact O-CG 3.48Å; D281-K285 PolarHBondContact O-N 3.38Å
282	Q	45.3	Very low	42.1	Very low	134 Å²	134	123.8 Å²	123.8	63%	0.626	58%	0.581	S	S	*	*	H	α-helix	trans	-70.3	-36	169.7	-96.5	-170.5	-27	0	0	112.6	I278 K279 K285 T286	I278-Q282 PolarHBondContact O-N 3.48Å; K279-Q282 PolarHBondContact O-N 2.95Å; Q282-K285 PolarHBondContact O-N 2.84Å; Q282-T286 WeakPolarHBondContact O-CB 3.41Å; Q282-T286 WeakPolarHBondContact O-CG2 3.4Å; Q282-T286 PolarHBondContact O-N 3.29Å; Q282-T286 PolarHBondContact O-OG1 3.22Å
283	E	44.3	Very low	41.9	Very low	97 Å²	97	126.4 Å²	126.4	45%	0.453	59%	0.592	S	S	.	*	H	α-helix	trans	-67.4	-34.2	171.2	-84	-177.1	167.4	0	0	112.3	K279 T286 R287	K279-E283 WeakPolarHBondContact O-CB 3.49Å; K279-E283 PolarHBondContact O-N 3.48Å; E283-T286 WeakPolarHBondContact CA-OG1 3.32Å; E283-T286 PolarHBondContact O-OG1 2.95Å; E283-R287 WeakPolarHBondContact O-CB 3.36Å; E283-R287 WeakPolarHBondContact O-CG 3.38Å; E283-R287 PolarHBondContact O-N 3.49Å; E283-R287 VanDerWaalsContact O-N 3.1Å
284	R	40.4	Very low	41.7	Very low	167 Å²	167	120.7 Å²	120.7	63%	0.63	58%	0.581	S	S	*	*	H	α-helix	trans	-65	-51.2	169.6	-84.6	179.7	-179.6	178.3	-1.1	111	K280 D281 T286 R287 F288	K280-R284 PolarHBondContact O-N 3.41Å; D281-R284 PolarHBondContact O-N 2.87Å; R284-T286 VanDerWaalsContact C-N 3.33Å; R284-T286 PolarHBondContact O-N 3.45Å; R284-R287 PolarHBondContact O-N 3.41Å; R284-F288 HydrophobicContact CB-CE2 4.5Å; R284-F288 WeakPolarHBondContact O-CD2 3.47Å; R284-F288 PolarHBondContact O-N 3.36Å
285	K	42.3	Very low	41	Very low	153 Å²	153	124.6 Å²	124.6	67%	0.665	59%	0.59	S	S	*	*	H	α-helix	trans	-64	-34.2	-178	-75.8	-179.5	179.4	179.7	0	113.3	D281 Q282 V289	D281-K285 WeakPolarHBondContact O-CB 3.39Å; D281-K285 WeakPolarHBondContact O-CG 3.48Å; D281-K285 PolarHBondContact O-N 3.38Å; Q282-K285 PolarHBondContact O-N 2.84Å; K285-V289 WeakPolarHBondContact O-CG2 3.38Å; K285-V289 PolarHBondContact O-N 2.88Å
286	T	41.9	Very low	40.7	Very low	88 Å²	88	123.1 Å²	123.1	54%	0.54	59%	0.59	S	S	.	*	H	α-helix	trans	-77.9	-31	176.3	50.9	0	0	0	0	113.1	Q282 E283 R284 F288 V289 T290	Q282-T286 WeakPolarHBondContact O-CB 3.41Å; Q282-T286 WeakPolarHBondContact O-CG2 3.4Å; Q282-T286 PolarHBondContact O-N 3.29Å; Q282-T286 PolarHBondContact O-OG1 3.22Å; E283-T286 WeakPolarHBondContact CA-OG1 3.32Å; E283-T286 PolarHBondContact O-OG1 2.95Å; R284-T286 VanDerWaalsContact C-N 3.33Å; R284-T286 PolarHBondContact O-N 3.45Å; T286-F288 VanDerWaalsContact C-N 3.3Å; T286-F288 PolarHBondContact O-N 3.42Å; T286-V289 PolarHBondContact O-N 2.99Å; T286-T290 PolarHBondContact O-N 3.46Å; T286-T290 PolarHBondContact O-OG1 2.92Å
287	R	36.6	Very low	40.2	Very low	178 Å²	178	128 Å²	128	67%	0.672	60%	0.603	S	S	*	*	H	α-helix	trans	-64.7	-30.3	170	-82.5	-176.8	-167.5	-177.6	6	113.5	E283 R284 L291	E283-R287 WeakPolarHBondContact O-CB 3.36Å; E283-R287 WeakPolarHBondContact O-CG 3.38Å; E283-R287 PolarHBondContact O-N 3.49Å; E283-R287 VanDerWaalsContact O-N 3.1Å; R284-R287 PolarHBondContact O-N 3.41Å; R287-L291 WeakPolarHBondContact O-CD1 3.35Å
288	F	36.6	Very low	39.9	Very low	144 Å²	144	125.3 Å²	125.3	63%	0.632	60%	0.598	S	S	*	*	H	α-helix	trans	-83.9	-20.4	179	-73	-69	0	0	0	114.2	R284 T286 L291	R284-F288 HydrophobicContact CB-CE2 4.5Å; R284-F288 WeakPolarHBondContact O-CD2 3.47Å; R284-F288 PolarHBondContact O-N 3.36Å; T286-F288 VanDerWaalsContact C-N 3.3Å; T286-F288 PolarHBondContact O-N 3.42Å; F288-L291 HydrophobicContact CD1-CD2 4.49Å
289	V	36.8	Very low	39.4	Very low	110 Å²	110	125.4 Å²	125.4	67%	0.667	60%	0.596	S	S	*	*	H	α-helix	trans	-85.8	-34.2	179.3	176.3	0	0	0	0	112	K285 T286 L291	K285-V289 WeakPolarHBondContact O-CG2 3.38Å; K285-V289 PolarHBondContact O-N 2.88Å; T286-V289 PolarHBondContact O-N 2.99Å; V289-L291 PolarHBondContact O-N 3.27Å
290	T	36.5	Very low	38.9	Very low	109 Å²	109	122.4 Å²	122.4	67%	0.669	59%	0.593	S	S	*	*	T	Hydrogen-bonded Turn	trans	-76.2	-8.2	170.8	48.3	0	0	0	0	113.7	T286	T286-T290 PolarHBondContact O-N 3.46Å; T286-T290 PolarHBondContact O-OG1 2.92Å
291	L	36.8	Very low	38.3	Very low	67 Å²	67	121.3 Å²	121.3	35%	0.351	59%	0.593	S	S	.	*	H	α-helix	trans	-77.6	-23.8	177.9	-130.4	85.1	0	0	0	112.4	R287 F288 V289 Y295	R287-L291 WeakPolarHBondContact O-CD1 3.35Å; F288-L291 HydrophobicContact CD1-CD2 4.49Å; V289-L291 PolarHBondContact O-N 3.27Å; L291-Y295 HydrophobicContact CB-CD2 4.29Å; L291-Y295 HydrophobicContact CB-CE2 4.41Å; L291-Y295 HydrophobicContact CD1-CE2 4.26Å; L291-Y295 HydrophobicContact CD2-CD2 3.79Å; L291-Y295 HydrophobicContact CD2-CE2 3.12Å; L291-Y295 HydrophobicContact CG-CD2 3.59Å; L291-Y295 HydrophobicContact CG-CE2 3.32Å; L291-Y295 VanDerWaalsContact O-CB 3.22Å; L291-Y295 WeakPolarHBondContact O-CB 3.32Å; L291-Y295 WeakPolarHBondContact O-CD2 3.43Å; L291-Y295 PolarHBondContact O-N 3.16Å; L291-Y295 VanDerWaalsContact O-N 3.17Å
292	K	36.6	Very low	37.9	Very low	179 Å²	179	121 Å²	121	78%	0.778	59%	0.59	S	S	*	*	H	α-helix	trans	-76.3	-29.1	-170.5	-143.1	176.6	-177.4	-176.4	0	113.8
293	D	38.6	Very low	37.3	Very low	148 Å²	148	121.2 Å²	121.2	79%	0.791	59%	0.59	S	S	*	*	H	α-helix	trans	-99.5	-12.9	179.9	-63.7	-27.2	0	0	0	113.6
294	G	35.5	Very low	36.9	Very low	36 Å²	36	119.8 Å²	119.8	37%	0.371	59%	0.589	S	S	.	*	H	α-helix	trans	-93.1	-17.5	171.7	0	0	0	0	0	114.4	H298	G294-H298 PolarHBondContact O-N 3.03Å
295	Y	31.4	Very low	36.4	Very low	130 Å²	130	115.7 Å²	115.7	51%	0.51	59%	0.585	S	S	.	*	H	α-helix	trans	-70.9	-29.9	-176.1	-110.3	-118.6	0	0	0	114.2	L291 R297 H298 Q299	L291-Y295 HydrophobicContact CB-CD2 4.29Å; L291-Y295 HydrophobicContact CB-CE2 4.41Å; L291-Y295 HydrophobicContact CD1-CE2 4.26Å; L291-Y295 HydrophobicContact CD2-CD2 3.79Å; L291-Y295 HydrophobicContact CD2-CE2 3.12Å; L291-Y295 HydrophobicContact CG-CD2 3.59Å; L291-Y295 HydrophobicContact CG-CE2 3.32Å; L291-Y295 VanDerWaalsContact O-CB 3.22Å; L291-Y295 WeakPolarHBondContact O-CB 3.32Å; L291-Y295 WeakPolarHBondContact O-CD2 3.43Å; L291-Y295 PolarHBondContact O-N 3.16Å; L291-Y295 VanDerWaalsContact O-N 3.17Å; Y295-R297 PolarHBondContact O-N 3.28Å; Y295-H298 PolarHBondContact O-N 2.94Å; Y295-Q299 PolarHBondContact O-N 2.82Å
296	S	35.4	Very low	36	Very low	91 Å²	91	112 Å²	112	64%	0.636	58%	0.575	S	S	*	*	H	α-helix	trans	-74.2	-26.3	179.9	80.9	0	0	0	0	113
297	R	35.4	Very low	35.7	Very low	214 Å²	214	112.1 Å²	112.1	81%	0.808	57%	0.571	S	S	*	*	H	α-helix	trans	-87.3	-18.9	173	-92	-176.2	178.2	170.9	1	114.1	Y295 S300	Y295-R297 PolarHBondContact O-N 3.28Å; R297-S300 PolarHBondContact O-OG 3.06Å
298	H	36.7	Very low	36	Very low	121 Å²	121	107.6 Å²	107.6	56%	0.56	56%	0.56	S	S	*	*	H	α-helix	trans	-87.2	-28	174.2	-113.4	-29.1	0	0	0	113.1	G294 Y295 S300 N301 I302	G294-H298 PolarHBondContact O-N 3.03Å; Y295-H298 PolarHBondContact O-N 2.94Å; H298-S300 VanDerWaalsContact C-N 3.31Å; H298-S300 PolarHBondContact O-N 3.21Å; H298-N301 PolarHBondContact O-N 2.99Å; H298-I302 HydrophobicContact CB-CD1 4.27Å; H298-I302 VanDerWaalsContact O-CD1 3.31Å; H298-I302 WeakPolarHBondContact O-CD1 3.26Å; H298-I302 WeakPolarHBondContact O-CG1 3.19Å; H298-I302 PolarHBondContact O-N 2.91Å
299	Q	36.7	Very low	36.2	Very low	107 Å²	107	105.4 Å²	105.4	50%	0.5	56%	0.555	S	S	.	*	H	α-helix	trans	-62.5	-33.3	176.7	-106.2	174.3	-20.7	0	0	113.6	Y295 N301 I302 F303	Y295-Q299 PolarHBondContact O-N 2.82Å; Q299-N301 VanDerWaalsContact C-N 3.28Å; Q299-N301 PolarHBondContact O-N 3.47Å; Q299-I302 PolarHBondContact O-N 3.03Å; Q299-F303 WeakPolarHBondContact O-CD2 3.25Å; Q299-F303 PolarHBondContact O-N 2.96Å
300	S	36.2	Very low	36.1	Very low	78 Å²	78	104.8 Å²	104.8	55%	0.545	55%	0.548	S	S	.	.	H	α-helix	trans	-69.9	-20.9	179.6	61.2	0	0	0	0	114.3	R297 H298 P304	R297-S300 PolarHBondContact O-OG 3.06Å; H298-S300 VanDerWaalsContact C-N 3.31Å; H298-S300 PolarHBondContact O-N 3.21Å; S300-P304 WeakPolarHBondContact O-CD 3.31Å; S300-P304 WeakPolarHBondContact O-CG 3.46Å
301	N	38.1	Very low	36.4	Very low	106 Å²	106	104.3 Å²	104.3	57%	0.567	54%	0.541	S	S	*	.	H	α-helix	trans	-100.4	-16	175.4	-77.7	-19.2	0	0	0	113.6	H298 Q299 C305	H298-N301 PolarHBondContact O-N 2.99Å; Q299-N301 VanDerWaalsContact C-N 3.28Å; Q299-N301 PolarHBondContact O-N 3.47Å; N301-C305 PolarHBondContact O-N 3.02Å
302	I	37.8	Very low	37.3	Very low	83 Å²	83	105.4 Å²	105.4	43%	0.426	54%	0.543	S	S	.	.	H	α-helix	trans	-76	-42.8	177.5	-69.2	162.6	0	0	0	110.7	H298 Q299 C305 V306	H298-I302 HydrophobicContact CB-CD1 4.27Å; H298-I302 VanDerWaalsContact O-CD1 3.31Å; H298-I302 WeakPolarHBondContact O-CD1 3.26Å; H298-I302 WeakPolarHBondContact O-CG1 3.19Å; H298-I302 PolarHBondContact O-N 2.91Å; Q299-I302 PolarHBondContact O-N 3.03Å; I302-C305 PolarHBondContact O-N 2.93Å; I302-V306 HydrophobicContact CG2-CG2 4.04Å; I302-V306 WeakPolarHBondContact O-CG2 3.43Å; I302-V306 PolarHBondContact O-N 3.34Å
303	F	31.8	Very low	37.7	Very low	139 Å²	139	103.5 Å²	103.5	61%	0.61	54%	0.538	S	S	*	.	H	α-helix	trans	-57.2	-50.8	176.9	-87.2	-79.3	0	0	0	113.8	Q299 C305 V306 I307	Q299-F303 WeakPolarHBondContact O-CD2 3.25Å; Q299-F303 PolarHBondContact O-N 2.96Å; F303-C305 VanDerWaalsContact C-N 3.31Å; F303-C305 PolarHBondContact O-N 3.38Å; F303-V306 PolarHBondContact O-N 2.9Å; F303-I307 WeakPolarHBondContact O-CB 3.12Å; F303-I307 WeakPolarHBondContact O-CD1 3.17Å; F303-I307 WeakPolarHBondContact O-CG1 3.41Å; F303-I307 PolarHBondContact O-N 3.2Å
304	P	36.1	Very low	38.1	Very low	68 Å²	68	102.3 Å²	102.3	44%	0.442	53%	0.528	S	S	.	.	H	α-helix	trans	-66.9	-29.4	177.5	22.5	-30.9	0	0	0	112.9	S300 N308	S300-P304 WeakPolarHBondContact O-CD 3.31Å; S300-P304 WeakPolarHBondContact O-CG 3.46Å; P304-N308 WeakPolarHBondContact O-CB 3.07Å; P304-N308 PolarHBondContact O-N 2.99Å
305	C	31	Very low	39.7	Very low	81 Å²	81	105.6 Å²	105.6	55%	0.547	54%	0.537	S	S	.	.	H	α-helix	trans	-71.7	-41.1	175.1	-91.6	0	0	0	0	113.4	N301 I302 F303 N309	N301-C305 PolarHBondContact O-N 3.02Å; I302-C305 PolarHBondContact O-N 2.93Å; F303-C305 VanDerWaalsContact C-N 3.31Å; F303-C305 PolarHBondContact O-N 3.38Å; C305-N309 WeakPolarHBondContact O-CB 3.38Å; C305-N309 PolarHBondContact O-N 3.28Å
306	V	34.1	Very low	41.5	Very low	75 Å²	75	103.7 Å²	103.7	46%	0.455	54%	0.535	S	S	.	.	H	α-helix	trans	-67.9	-46.2	177.4	176.3	0	0	0	0	109.9	I302 F303 N308 N309 D310	I302-V306 HydrophobicContact CG2-CG2 4.04Å; I302-V306 WeakPolarHBondContact O-CG2 3.43Å; I302-V306 PolarHBondContact O-N 3.34Å; F303-V306 PolarHBondContact O-N 2.9Å; V306-N308 VanDerWaalsContact C-N 3.35Å; V306-N308 PolarHBondContact O-N 2.85Å; V306-N309 PolarHBondContact O-N 3.42Å; V306-D310 PolarHBondContact O-N 3.47Å
307	I	34.2	Very low	43.4	Very low	90 Å²	90	108.9 Å²	108.9	46%	0.462	54%	0.541	S	S	.	.	H	α-helix	trans	-60.8	-43	176.2	-65.8	166.1	0	0	0	110.9	F303 N309 D310 I311	F303-I307 WeakPolarHBondContact O-CB 3.12Å; F303-I307 WeakPolarHBondContact O-CD1 3.17Å; F303-I307 WeakPolarHBondContact O-CG1 3.41Å; F303-I307 PolarHBondContact O-N 3.2Å; I307-N309 PolarHBondContact O-N 2.83Å; I307-D310 PolarHBondContact O-N 3.44Å; I307-I311 HydrophobicContact CG2-CD1 3.54Å; I307-I311 HydrophobicContact CG2-CG1 4.24Å; I307-I311 WeakPolarHBondContact O-CB 3.42Å; I307-I311 WeakPolarHBondContact O-CD1 3.3Å; I307-I311 WeakPolarHBondContact O-CG1 3.35Å; I307-I311 PolarHBondContact O-N 2.99Å
308	N	42.7	Very low	45.5	Very low	83 Å²	83	102.8 Å²	102.8	44%	0.444	52%	0.523	S	S	.	.	H	α-helix	trans	-70.2	-32.5	179.7	-161	11.5	0	0	0	112.4	P304 V306 K312	P304-N308 WeakPolarHBondContact O-CB 3.07Å; P304-N308 PolarHBondContact O-N 2.99Å; V306-N308 VanDerWaalsContact C-N 3.35Å; V306-N308 PolarHBondContact O-N 2.85Å; N308-K312 VanDerWaalsContact O-CB 3.31Å; N308-K312 WeakPolarHBondContact O-CB 3.49Å; N308-K312 WeakPolarHBondContact O-CG 3.36Å; N308-K312 PolarHBondContact O-N 3.49Å
309	N	41.6	Very low	47.7	Very low	98 Å²	98	100.6 Å²	100.6	52%	0.524	51%	0.51	S	S	.	.	H	α-helix	trans	-71.1	-40.8	173	-79.6	-15.2	0	0	0	112.1	C305 V306 I307 K312 M313	C305-N309 WeakPolarHBondContact O-CB 3.38Å; C305-N309 PolarHBondContact O-N 3.28Å; V306-N309 PolarHBondContact O-N 3.42Å; I307-N309 PolarHBondContact O-N 2.83Å; N309-K312 PolarHBondContact O-N 3.14Å; N309-M313 WeakPolarHBondContact O-CB 3.36Å; N309-M313 WeakPolarHBondContact O-CG 3.41Å; N309-M313 PolarHBondContact O-N 3.49Å
310	D	33.6	Very low	49.9	Very low	97 Å²	97	98 Å²	98	52%	0.519	50%	0.499	S	S	.	.	H	α-helix	trans	-66.5	-42.4	176	-74.6	-22.6	0	0	0	111.4	V306 I307 K312 M313 H314	V306-D310 PolarHBondContact O-N 3.47Å; I307-D310 PolarHBondContact O-N 3.44Å; D310-K312 PolarHBondContact O-N 2.83Å; D310-M313 PolarHBondContact O-N 3.21Å; D310-H314 WeakPolarHBondContact O-CB 3.5Å; D310-H314 PolarHBondContact O-N 3.37Å
311	I	43.9	Very low	52.3	Low	100 Å²	100	100.2 Å²	100.2	51%	0.513	50%	0.499	S	S	.	.	H	α-helix	trans	-61.2	-44.3	173.4	-69	167.2	0	0	0	110.4	I307 H314 N315	I307-I311 HydrophobicContact CG2-CD1 3.54Å; I307-I311 HydrophobicContact CG2-CG1 4.24Å; I307-I311 WeakPolarHBondContact O-CB 3.42Å; I307-I311 WeakPolarHBondContact O-CD1 3.3Å; I307-I311 WeakPolarHBondContact O-CG1 3.35Å; I307-I311 PolarHBondContact O-N 2.99Å; I311-H314 PolarHBondContact O-N 3.28Å; I311-N315 VanDerWaalsContact O-CB 3.24Å; I311-N315 WeakPolarHBondContact O-CB 3.48Å; I311-N315 PolarHBondContact O-N 3.38Å
312	K	55.1	Low	54.7	Low	90 Å²	90	99.1 Å²	99.1	39%	0.391	49%	0.492	S	S	.	.	H	α-helix	trans	-64.2	-41.3	176.4	-78.8	177.4	179.7	-173.6	0	112.3	N308 N309 D310 N315 N316	N308-K312 VanDerWaalsContact O-CB 3.31Å; N308-K312 WeakPolarHBondContact O-CB 3.49Å; N308-K312 WeakPolarHBondContact O-CG 3.36Å; N308-K312 PolarHBondContact O-N 3.49Å; N309-K312 PolarHBondContact O-N 3.14Å; D310-K312 PolarHBondContact O-N 2.83Å; K312-N315 PolarHBondContact O-N 3.03Å; K312-N316 WeakPolarHBondContact O-CB 3.38Å; K312-N316 VanDerWaalsContact O-CG 3.26Å; K312-N316 PolarHBondContact O-N 3.41Å
313	M	46.5	Very low	57.2	Low	139 Å²	139	95.2 Å²	95.2	69%	0.685	47%	0.472	S	S	*	.	H	α-helix	trans	-65.9	-42.1	176	-76.3	-168.4	76.9	0	0	111.8	N309 D310 N316 R317	N309-M313 WeakPolarHBondContact O-CB 3.36Å; N309-M313 WeakPolarHBondContact O-CG 3.41Å; N309-M313 PolarHBondContact O-N 3.49Å; D310-M313 PolarHBondContact O-N 3.21Å; M313-N316 PolarHBondContact O-N 3.29Å; M313-R317 WeakPolarHBondContact O-CB 3.19Å; M313-R317 PolarHBondContact O-N 3.15Å
314	H	46.9	Very low	60	Low	122 Å²	122	91 Å²	91	57%	0.565	46%	0.456	S	S	*	.	H	α-helix	trans	-64	-44.4	175.7	-168.4	-70	0	0	0	111.3	D310 I311 N316 R317 M318	D310-H314 WeakPolarHBondContact O-CB 3.5Å; D310-H314 PolarHBondContact O-N 3.37Å; I311-H314 PolarHBondContact O-N 3.28Å; H314-N316 PolarHBondContact O-N 2.89Å; H314-R317 PolarHBondContact O-N 3.03Å; H314-M318 VanDerWaalsContact CE1-CG 3.49Å; H314-M318 WeakPolarHBondContact CE1-CG 3.17Å; H314-M318 WeakPolarHBondContact O-CG 3.15Å; H314-M318 PolarHBondContact O-N 3.18Å
315	N	67.7	Low	62.7	Low	106 Å²	106	91.2 Å²	91.2	57%	0.567	45%	0.452	S	S	*	.	H	α-helix	trans	-63.1	-42.4	178.3	-162.6	19.3	0	0	0	111.5	I311 K312 R317 M318 W319	I311-N315 VanDerWaalsContact O-CB 3.24Å; I311-N315 WeakPolarHBondContact O-CB 3.48Å; I311-N315 PolarHBondContact O-N 3.38Å; K312-N315 PolarHBondContact O-N 3.03Å; N315-R317 VanDerWaalsContact C-N 3.34Å; N315-R317 PolarHBondContact O-N 2.87Å; N315-M318 PolarHBondContact O-N 3.42Å; N315-W319 WeakPolarHBondContact O-CB 3.29Å; N315-W319 PolarHBondContact O-N 2.71Å
316	N	70.9	Confident	65.5	Low	89 Å²	89	88.6 Å²	88.6	48%	0.476	44%	0.435	S	S	.	.	H	α-helix	trans	-65.1	-35.9	175.2	-74.5	-9.1	0	0	0	112.6	K312 M313 H314 N320	K312-N316 WeakPolarHBondContact O-CB 3.38Å; K312-N316 VanDerWaalsContact O-CG 3.26Å; K312-N316 PolarHBondContact O-N 3.41Å; M313-N316 PolarHBondContact O-N 3.29Å; H314-N316 PolarHBondContact O-N 2.89Å; N316-N320 WeakPolarHBondContact O-CB 3.33Å; N316-N320 VanDerWaalsContact O-CG 3.27Å; N316-N320 PolarHBondContact O-N 3.49Å; N316-N320 PolarHBondContact O-ND2 2.93Å
317	R	74.6	Confident	68.3	Low	200 Å²	200	85 Å²	85	76%	0.755	41%	0.413	S	S	*	.	H	α-helix	trans	-69.1	-43.9	176.5	-170.4	177	-178.3	176.9	-0.9	111.7	M313 H314 N315 W319 N320 F321	M313-R317 WeakPolarHBondContact O-CB 3.19Å; M313-R317 PolarHBondContact O-N 3.15Å; H314-R317 PolarHBondContact O-N 3.03Å; N315-R317 VanDerWaalsContact C-N 3.34Å; N315-R317 PolarHBondContact O-N 2.87Å; R317-W319 VanDerWaalsContact C-N 3.35Å; R317-N320 PolarHBondContact O-N 3.2Å; R317-F321 PolarHBondContact O-N 3.46Å
318	M	79.8	Confident	71.1	Confident	86 Å²	86	83 Å²	83	42%	0.424	41%	0.405	S	S	.	.	H	α-helix	trans	-62.7	-42.8	174.9	-73.1	-60.1	-64.8	0	0	111.3	H314 N315 F321 I322	H314-M318 VanDerWaalsContact CE1-CG 3.49Å; H314-M318 WeakPolarHBondContact CE1-CG 3.17Å; H314-M318 WeakPolarHBondContact O-CG 3.15Å; H314-M318 PolarHBondContact O-N 3.18Å; N315-M318 PolarHBondContact O-N 3.42Å; M318-F321 WeakPolarHBondContact O-CB 2.95Å; M318-F321 PolarHBondContact O-N 3.21Å; M318-I322 VanDerWaalsContact O-CG1 3.27Å; M318-I322 WeakPolarHBondContact O-CG1 3.3Å; M318-I322 PolarHBondContact O-N 3.09Å
319	W	82.3	Confident	73.5	Confident	76 Å²	76	81.6 Å²	81.6	29%	0.288	40%	0.401	S	S	.	.	H	α-helix	trans	-58.1	-49.8	174.8	180	-104.6	0	0	0	111.9	F192 L196 N315 R317 F321 I322 V323	F192-W319 HydrophobicContact CD1-CH2 4.26Å; F192-W319 AromaticContact CD1-CZ2 3.94Å; F192-W319 HydrophobicContact CD1-CZ2 3.94Å; F192-W319 AromaticContact CE1-CH2 3.91Å; F192-W319 HydrophobicContact CE1-CH2 3.91Å; F192-W319 AromaticContact CE1-CZ2 3.99Å; F192-W319 HydrophobicContact CE1-CZ2 3.99Å; L196-W319 HydrophobicContact CD1-CH2 4.35Å; L196-W319 HydrophobicContact CD1-CZ2 3.93Å; N315-W319 WeakPolarHBondContact O-CB 3.29Å; N315-W319 PolarHBondContact O-N 2.71Å; R317-W319 VanDerWaalsContact C-N 3.35Å; W319-F321 VanDerWaalsContact C-N 3.25Å; W319-F321 PolarHBondContact O-N 3.38Å; W319-I322 PolarHBondContact O-N 3.41Å; W319-V323 HydrophobicContact CD2-CG2 4.14Å; W319-V323 HydrophobicContact CG-CG2 4.44Å; W319-V323 HydrophobicContact CZ2-CG2 3.87Å; W319-V323 WeakPolarHBondContact O-CB 3.28Å; W319-V323 VanDerWaalsContact O-CG2 3.31Å; W319-V323 WeakPolarHBondContact O-CG2 3.22Å; W319-V323 PolarHBondContact O-N 3.33Å
320	N	82.7	Confident	75.8	Confident	52 Å²	52	80.7 Å²	80.7	28%	0.278	40%	0.396	S	S	.	.	H	α-helix	trans	-59.1	-37.9	177	-74.9	-22.2	0	0	0	112.4	N316 R317 I324	N316-N320 WeakPolarHBondContact O-CB 3.33Å; N316-N320 VanDerWaalsContact O-CG 3.27Å; N316-N320 PolarHBondContact O-N 3.49Å; N316-N320 PolarHBondContact O-ND2 2.93Å; R317-N320 PolarHBondContact O-N 3.2Å; N320-I324 WeakPolarHBondContact O-CD1 3.49Å; N320-I324 WeakPolarHBondContact O-CG1 3.31Å; N320-I324 PolarHBondContact O-N 3.08Å; N320-I324 VanDerWaalsContact O-N 3.08Å
321	F	86.5	Confident	78.5	Confident	125 Å²	125	76.1 Å²	76.1	55%	0.548	37%	0.371	S	S	.	.	H	α-helix	trans	-67.8	-46.2	177.3	-175.1	-108.5	0	0	0	111.9	R317 M318 W319 V323 I324 I325	R317-F321 PolarHBondContact O-N 3.46Å; M318-F321 WeakPolarHBondContact O-CB 2.95Å; M318-F321 PolarHBondContact O-N 3.21Å; W319-F321 VanDerWaalsContact C-N 3.25Å; W319-F321 PolarHBondContact O-N 3.38Å; F321-V323 VanDerWaalsContact C-N 3.34Å; F321-V323 PolarHBondContact O-N 2.95Å; F321-I324 PolarHBondContact O-N 3.5Å; F321-I325 HydrophobicContact CD1-CD1 3.62Å; F321-I325 HydrophobicContact CD2-CD1 4.47Å; F321-I325 HydrophobicContact CE1-CD1 3.16Å; F321-I325 HydrophobicContact CE1-CG1 4.33Å; F321-I325 HydrophobicContact CE2-CD1 4.09Å; F321-I325 HydrophobicContact CG-CD1 4.27Å; F321-I325 HydrophobicContact CZ-CD1 3.44Å; F321-I325 VanDerWaalsContact CZ-CD1 3.44Å; F321-I325 HydrophobicContact CZ-CG1 4.34Å; F321-I325 WeakPolarHBondContact O-CG1 3.36Å; F321-I325 PolarHBondContact O-N 2.92Å
322	I	89.3	Confident	80.6	Confident	83 Å²	83	75 Å²	75	43%	0.426	37%	0.366	S	S	.	.	H	α-helix	trans	-58.5	-47.2	175.6	-68.5	164.3	0	0	0	110	M318 W319 I324 I325 S326	M318-I322 VanDerWaalsContact O-CG1 3.27Å; M318-I322 WeakPolarHBondContact O-CG1 3.3Å; M318-I322 PolarHBondContact O-N 3.09Å; W319-I322 PolarHBondContact O-N 3.41Å; I322-I324 PolarHBondContact O-N 3.14Å; I322-I325 PolarHBondContact O-N 3.23Å; I322-S326 WeakPolarHBondContact O-CB 3.17Å; I322-S326 PolarHBondContact O-N 3.31Å; I322-S326 PolarHBondContact O-OG 2.98Å; I322-S326 VanDerWaalsContact O-OG 3.05Å
323	V	89.5	Confident	82.1	Confident	1 Å²	1	77.7 Å²	77.7	1%	0.006	38%	0.378	C	S	.	.	H	α-helix	trans	-59.5	-46.2	179	168.7	0	0	0	0	111.5	C123 F189 W319 F321 I325 S326 I327	C123-V323 VanDerWaalsContact SG-CG1 3.55Å; F189-V323 HydrophobicContact CB-CG1 3.65Å; F189-V323 HydrophobicContact CD1-CG2 4.37Å; F189-V323 HydrophobicContact CD2-CG1 4.41Å; F189-V323 HydrophobicContact CG-CG1 4.01Å; W319-V323 HydrophobicContact CD2-CG2 4.14Å; W319-V323 HydrophobicContact CG-CG2 4.44Å; W319-V323 HydrophobicContact CZ2-CG2 3.87Å; W319-V323 WeakPolarHBondContact O-CB 3.28Å; W319-V323 VanDerWaalsContact O-CG2 3.31Å; W319-V323 WeakPolarHBondContact O-CG2 3.22Å; W319-V323 PolarHBondContact O-N 3.33Å; F321-V323 VanDerWaalsContact C-N 3.34Å; F321-V323 PolarHBondContact O-N 2.95Å; V323-I325 PolarHBondContact O-N 3.46Å; V323-S326 PolarHBondContact O-N 2.92Å; V323-I327 HydrophobicContact CG1-CD1 3.71Å; V323-I327 HydrophobicContact CG1-CG1 4.4Å; V323-I327 VanDerWaalsContact O-CG1 3.22Å; V323-I327 WeakPolarHBondContact O-CG1 3.29Å; V323-I327 PolarHBondContact O-N 3.35Å
324	I	91.1	Very high	83.9	Confident	50 Å²	50	72.7 Å²	72.7	26%	0.256	36%	0.356	S	S	.	.	H	α-helix	trans	-62.3	-45.1	178	-68.2	165.7	0	0	0	110.8	N122 L126 N320 F321 I322 S326 I327 V328	N122-I324 HydrophobicContact CB-CD1 3.96Å; N122-I324 HydrophobicContact CB-CG1 4.43Å; L126-I324 HydrophobicContact CD1-CB 4.43Å; L126-I324 HydrophobicContact CD1-CG1 3.93Å; L126-I324 HydrophobicContact CD1-CG2 4.04Å; N320-I324 WeakPolarHBondContact O-CD1 3.49Å; N320-I324 WeakPolarHBondContact O-CG1 3.31Å; N320-I324 PolarHBondContact O-N 3.08Å; N320-I324 VanDerWaalsContact O-N 3.08Å; F321-I324 PolarHBondContact O-N 3.5Å; I322-I324 PolarHBondContact O-N 3.14Å; I324-S326 VanDerWaalsContact C-N 3.32Å; I324-S326 PolarHBondContact O-N 2.91Å; I324-I327 PolarHBondContact O-N 2.72Å; I324-V328 WeakPolarHBondContact O-CG2 3.4Å; I324-V328 PolarHBondContact O-N 3.15Å; I324-V328 VanDerWaalsContact O-N 3.13Å
325	I	92	Very high	85.6	Confident	73 Å²	73	67 Å²	67	37%	0.374	33%	0.329	S	S	.	.	H	α-helix	trans	-60.5	-44.5	176.1	-72.3	175.5	0	0	0	110.5	F321 I322 V323 I327 V328 C329	F321-I325 HydrophobicContact CD1-CD1 3.62Å; F321-I325 HydrophobicContact CD2-CD1 4.47Å; F321-I325 HydrophobicContact CE1-CD1 3.16Å; F321-I325 HydrophobicContact CE1-CG1 4.33Å; F321-I325 HydrophobicContact CE2-CD1 4.09Å; F321-I325 HydrophobicContact CG-CD1 4.27Å; F321-I325 HydrophobicContact CZ-CD1 3.44Å; F321-I325 VanDerWaalsContact CZ-CD1 3.44Å; F321-I325 HydrophobicContact CZ-CG1 4.34Å; F321-I325 WeakPolarHBondContact O-CG1 3.36Å; F321-I325 PolarHBondContact O-N 2.92Å; I322-I325 PolarHBondContact O-N 3.23Å; V323-I325 PolarHBondContact O-N 3.46Å; I325-I327 VanDerWaalsContact C-N 3.34Å; I325-I327 PolarHBondContact O-N 3.39Å; I325-V328 PolarHBondContact O-N 3.26Å; I325-C329 HydrophobicContact CG2-CB 4.4Å; I325-C329 VanDerWaalsContact O-CB 3.27Å; I325-C329 WeakPolarHBondContact O-CB 3.08Å; I325-C329 PolarHBondContact O-N 2.86Å
326	S	91.3	Very high	86.3	Confident	25 Å²	25	65.1 Å²	65.1	18%	0.175	32%	0.322	C	S	.	.	H	α-helix	trans	-61.6	-42.7	178.7	-66.2	0	0	0	0	111.9	I322 V323 I324 V328 L330	I322-S326 WeakPolarHBondContact O-CB 3.17Å; I322-S326 PolarHBondContact O-N 3.31Å; I322-S326 PolarHBondContact O-OG 2.98Å; I322-S326 VanDerWaalsContact O-OG 3.05Å; V323-S326 PolarHBondContact O-N 2.92Å; I324-S326 VanDerWaalsContact C-N 3.32Å; I324-S326 PolarHBondContact O-N 2.91Å; S326-V328 VanDerWaalsContact C-N 3.28Å; S326-V328 PolarHBondContact O-N 2.93Å; S326-L330 WeakPolarHBondContact O-CB 3.41Å; S326-L330 VanDerWaalsContact O-CG 3.3Å; S326-L330 WeakPolarHBondContact O-CG 3.43Å; S326-L330 PolarHBondContact O-N 3.47Å; S326-L330 VanDerWaalsContact O-N 3.08Å
327	I	92	Very high	86.8	Confident	1 Å²	1	66.8 Å²	66.8	1%	0.005	32%	0.322	C	S	.	.	H	α-helix	trans	-60.7	-37.8	177.3	-70.4	165.5	0	0	0	111.6	F130 L185 F189 V323 I324 I325 P331	F130-I327 HydrophobicContact CD2-CG2 4.46Å; F130-I327 HydrophobicContact CE2-CG2 3.82Å; L185-I327 HydrophobicContact CB-CG1 4.48Å; F189-I327 HydrophobicContact CD2-CD1 4.43Å; F189-I327 HydrophobicContact CD2-CG1 3.74Å; F189-I327 HydrophobicContact CE2-CG1 4.38Å; V323-I327 HydrophobicContact CG1-CD1 3.71Å; V323-I327 HydrophobicContact CG1-CG1 4.4Å; V323-I327 VanDerWaalsContact O-CG1 3.22Å; V323-I327 WeakPolarHBondContact O-CG1 3.29Å; V323-I327 PolarHBondContact O-N 3.35Å; I324-I327 PolarHBondContact O-N 2.72Å; I325-I327 VanDerWaalsContact C-N 3.34Å; I325-I327 PolarHBondContact O-N 3.39Å; I327-P331 VanDerWaalsContact O-CD 3.31Å; I327-P331 WeakPolarHBondContact O-CD 3.46Å; I327-P331 WeakPolarHBondContact O-CG 3.49Å
328	V	92.6	Very high	86.9	Confident	47 Å²	47	57.2 Å²	57.2	29%	0.285	29%	0.286	S	S	.	.	H	α-helix	trans	-85.5	-43.1	-176.6	174.4	0	0	0	0	112.1	F130 Y178 I324 I325 S326	F130-V328 HydrophobicContact CZ-CG2 4.26Å; Y178-V328 VanDerWaalsContact CE2-O 3.25Å; Y178-V328 WeakPolarHBondContact CE2-O 3.41Å; Y178-V328 WeakPolarHBondContact OH-CG1 3.38Å; Y178-V328 PolarHBondContact OH-O 3.42Å; Y178-V328 VanDerWaalsContact OH-O 3.12Å; I324-V328 WeakPolarHBondContact O-CG2 3.4Å; I324-V328 PolarHBondContact O-N 3.15Å; I324-V328 VanDerWaalsContact O-N 3.13Å; I325-V328 PolarHBondContact O-N 3.26Å; S326-V328 VanDerWaalsContact C-N 3.28Å; S326-V328 PolarHBondContact O-N 2.93Å
329	C	92.8	Very high	86.6	Confident	54 Å²	54	55.3 Å²	55.3	37%	0.365	28%	0.277	S	S	.	.	H	α-helix	trans	-91.6	-34.8	-169.5	-62.9	0	0	0	0	113.6	I325 I332	I325-C329 HydrophobicContact CG2-CB 4.4Å; I325-C329 VanDerWaalsContact O-CB 3.27Å; I325-C329 WeakPolarHBondContact O-CB 3.08Å; I325-C329 PolarHBondContact O-N 2.86Å; C329-I332 WeakPolarHBondContact O-CB 3.45Å; C329-I332 WeakPolarHBondContact O-CG1 3.32Å; C329-I332 PolarHBondContact O-N 3.24Å
330	L	91.1	Very high	86.3	Confident	78 Å²	78	57.8 Å²	57.8	41%	0.408	29%	0.287	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.9	-39.1	-177.5	-70	172.3	0	0	0	113.6	L185 F189 S326 I332 F333 P334	L185-L330 HydrophobicContact CD1-CB 3.76Å; L185-L330 HydrophobicContact CD1-CD1 4.39Å; F189-L330 HydrophobicContact CE2-CD1 4.39Å; F189-L330 HydrophobicContact CZ-CD1 4.3Å; S326-L330 WeakPolarHBondContact O-CB 3.41Å; S326-L330 VanDerWaalsContact O-CG 3.3Å; S326-L330 WeakPolarHBondContact O-CG 3.43Å; S326-L330 PolarHBondContact O-N 3.47Å; S326-L330 VanDerWaalsContact O-N 3.08Å; L330-I332 PolarHBondContact O-N 3.49Å; L330-I332 VanDerWaalsContact O-N 3.15Å; L330-F333 PolarHBondContact O-N 3.33Å; L330-P334 WeakPolarHBondContact O-CD 3.4Å
331	P	89.7	Confident	85.9	Confident	1 Å²	1	55.4 Å²	55.4	1%	0.006	27%	0.274	C	S	.	.	T	Hydrogen-bonded Turn	trans	-60.5	-21.6	177.4	-29.8	40.2	0	0	0	114.6	Y178 L181 S182 L185 I327 F333 P334 T335	Y178-P331 HydrophobicContact CD2-CB 3.73Å; Y178-P331 HydrophobicContact CE2-CB 4Å; L181-P331 HydrophobicContact CB-CB 3.88Å; L181-P331 HydrophobicContact CB-CG 4.17Å; S182-P331 WeakPolarHBondContact OG-CG 3.49Å; L185-P331 HydrophobicContact CD1-CG 3.57Å; I327-P331 VanDerWaalsContact O-CD 3.31Å; I327-P331 WeakPolarHBondContact O-CD 3.46Å; I327-P331 WeakPolarHBondContact O-CG 3.49Å; P331-F333 VanDerWaalsContact C-N 3.3Å; P331-F333 PolarHBondContact O-N 2.86Å; P331-P334 WeakPolarHBondContact O-CD 3.2Å; P331-P334 WeakPolarHBondContact O-CG 3.25Å; P331-T335 VanDerWaalsContact O-CG2 3.24Å; P331-T335 WeakPolarHBondContact O-CG2 3.3Å; P331-T335 PolarHBondContact O-N 2.99Å; P331-T335 PolarHBondContact O-OG1 3.04Å
332	I	89.1	Confident	85	Confident	78 Å²	78	49.9 Å²	49.9	40%	0.4	25%	0.251	S	S	.	.	H	α-helix	trans	-62.7	-39.1	-179.4	-57.7	175.3	0	0	0	110.6	Y178 C329 L330 T335 T336	Y178-I332 HydrophobicContact CD2-CG1 4.24Å; Y178-I332 HydrophobicContact CE2-CG1 3.86Å; C329-I332 WeakPolarHBondContact O-CB 3.45Å; C329-I332 WeakPolarHBondContact O-CG1 3.32Å; C329-I332 PolarHBondContact O-N 3.24Å; L330-I332 PolarHBondContact O-N 3.49Å; L330-I332 VanDerWaalsContact O-N 3.15Å; I332-T335 PolarHBondContact O-OG1 3.49Å; I332-T335 VanDerWaalsContact O-OG1 3.08Å; I332-T336 HydrophobicContact CG2-CG2 3.84Å; I332-T336 VanDerWaalsContact O-CB 3.3Å; I332-T336 WeakPolarHBondContact O-CB 3.41Å; I332-T336 VanDerWaalsContact O-CG2 3.26Å; I332-T336 WeakPolarHBondContact O-CG2 3.49Å; I332-T336 PolarHBondContact O-N 2.92Å; I332-T336 PolarHBondContact O-OG1 3.33Å
333	F	86.5	Confident	83.9	Confident	145 Å²	145	52.7 Å²	52.7	64%	0.636	26%	0.257	S	S	*	.	H	α-helix	trans	-62.8	-58.3	-177.3	-65.1	-76.7	0	0	0	113.5	L330 P331 T335 T336 Y337	L330-F333 PolarHBondContact O-N 3.33Å; P331-F333 VanDerWaalsContact C-N 3.3Å; P331-F333 PolarHBondContact O-N 2.86Å; F333-T335 VanDerWaalsContact C-N 3.31Å; F333-T335 PolarHBondContact O-N 3.31Å; F333-T336 PolarHBondContact O-OG1 3.43Å; F333-Y337 WeakPolarHBondContact O-CB 3.49Å; F333-Y337 PolarHBondContact O-N 3.46Å
334	P	84.5	Confident	83.2	Confident	35 Å²	35	59.6 Å²	59.6	23%	0.227	28%	0.284	C	S	.	.	H	α-helix	trans	-64.4	-33.6	179.3	26.5	-35.6	0	0	0	112.5	L181 L330 P331 G338 P377	L181-P334 HydrophobicContact CD1-CB 4.29Å; L181-P334 HydrophobicContact CD1-CG 3.73Å; L330-P334 WeakPolarHBondContact O-CD 3.4Å; P331-P334 WeakPolarHBondContact O-CD 3.2Å; P331-P334 WeakPolarHBondContact O-CG 3.25Å; P334-G338 PolarHBondContact O-N 3.44Å; P334-P377 HydrophobicContact CB-CG 4.48Å
335	T	82.4	Confident	82.1	Confident	2 Å²	2	62.3 Å²	62.3	1%	0.012	30%	0.299	C	S	.	.	H	α-helix	trans	-70.9	-49.2	-179.8	55.9	0	0	0	0	112.6	H177 L181 P331 I332 F333 G338 I339	H177-T335 HydrophobicContact CB-CG2 3.96Å; L181-T335 HydrophobicContact CD1-CG2 3.83Å; P331-T335 VanDerWaalsContact O-CG2 3.24Å; P331-T335 WeakPolarHBondContact O-CG2 3.3Å; P331-T335 PolarHBondContact O-N 2.99Å; P331-T335 PolarHBondContact O-OG1 3.04Å; I332-T335 PolarHBondContact O-OG1 3.49Å; I332-T335 VanDerWaalsContact O-OG1 3.08Å; F333-T335 VanDerWaalsContact C-N 3.31Å; F333-T335 PolarHBondContact O-N 3.31Å; T335-G338 PolarHBondContact O-N 3.08Å; T335-I339 WeakPolarHBondContact O-CD1 3.32Å; T335-I339 WeakPolarHBondContact O-CG1 3.35Å; T335-I339 PolarHBondContact O-N 3.26Å; T335-I339 VanDerWaalsContact O-N 3.08Å
336	T	81.8	Confident	80.6	Confident	67 Å²	67	65 Å²	65	41%	0.411	31%	0.314	S	S	.	.	H	α-helix	trans	-65.1	-41.6	177.3	55.9	0	0	0	0	111.3	I332 F333 G338 I339 W340	I332-T336 HydrophobicContact CG2-CG2 3.84Å; I332-T336 VanDerWaalsContact O-CB 3.3Å; I332-T336 WeakPolarHBondContact O-CB 3.41Å; I332-T336 VanDerWaalsContact O-CG2 3.26Å; I332-T336 WeakPolarHBondContact O-CG2 3.49Å; I332-T336 PolarHBondContact O-N 2.92Å; I332-T336 PolarHBondContact O-OG1 3.33Å; F333-T336 PolarHBondContact O-OG1 3.43Å; T336-G338 VanDerWaalsContact C-N 3.35Å; T336-G338 PolarHBondContact O-N 2.87Å; T336-I339 PolarHBondContact O-N 3.23Å; T336-W340 VanDerWaalsContact O-CB 3.28Å; T336-W340 WeakPolarHBondContact O-CB 3.42Å; T336-W340 PolarHBondContact O-N 3.38Å
337	Y	82.2	Confident	79	Confident	123 Å²	123	65.7 Å²	65.7	48%	0.482	32%	0.315	S	S	.	.	H	α-helix	trans	-62.5	-41.1	174.7	-178.6	-101.7	0	0	0	111.9	F333 W340 A341 L373	F333-Y337 WeakPolarHBondContact O-CB 3.49Å; F333-Y337 PolarHBondContact O-N 3.46Å; Y337-W340 HydrophobicContact CD2-CE3 4.01Å; Y337-W340 HydrophobicContact CD2-CZ3 4.41Å; Y337-W340 AromaticContact CE2-CE3 3.81Å; Y337-W340 HydrophobicContact CE2-CE3 3.81Å; Y337-W340 AromaticContact CE2-CZ3 3.77Å; Y337-W340 HydrophobicContact CE2-CZ3 3.77Å; Y337-W340 PolarHBondContact O-N 2.86Å; Y337-A341 HydrophobicContact CE1-CB 4.5Å; Y337-A341 VanDerWaalsContact O-CB 3.24Å; Y337-A341 WeakPolarHBondContact O-CB 3.34Å; Y337-A341 PolarHBondContact O-N 3.46Å; Y337-L373 HydrophobicContact CD1-CD1 3.92Å; Y337-L373 HydrophobicContact CD1-CD2 3.89Å; Y337-L373 HydrophobicContact CD1-CG 4.31Å; Y337-L373 HydrophobicContact CE1-CD1 3.75Å; Y337-L373 HydrophobicContact CE1-CD2 3.89Å; Y337-L373 HydrophobicContact CE1-CG 4.42Å
338	G	76.5	Confident	77	Confident	0 Å²	0	68.3 Å²	68.3	0%	0	33%	0.329	C	S	.	.	H	α-helix	trans	-69.1	-34.4	-179.6	0	0	0	0	0	114.1	P334 T335 T336 S342 Y370 L373	P334-G338 PolarHBondContact O-N 3.44Å; T335-G338 PolarHBondContact O-N 3.08Å; T336-G338 VanDerWaalsContact C-N 3.35Å; T336-G338 PolarHBondContact O-N 2.87Å; G338-S342 WeakPolarHBondContact O-CB 3.48Å; G338-S342 PolarHBondContact O-N 3.4Å; G338-Y370 WeakPolarHBondContact O-CE2 3.3Å; G338-L373 VanDerWaalsContact CA-CD2 3.48Å
339	I	72.4	Confident	74.8	Confident	46 Å²	46	68.1 Å²	68.1	24%	0.236	33%	0.33	C	S	.	.	H	α-helix	trans	-71.3	-40.8	172.8	-66.2	158.5	0	0	0	111.1	L174 T335 T336 S342 Y343	L174-I339 HydrophobicContact CB-CD1 3.46Å; L174-I339 VanDerWaalsContact CB-CD1 3.46Å; L174-I339 HydrophobicContact CD1-CD1 3.24Å; L174-I339 HydrophobicContact CG-CD1 3.58Å; T335-I339 WeakPolarHBondContact O-CD1 3.32Å; T335-I339 WeakPolarHBondContact O-CG1 3.35Å; T335-I339 PolarHBondContact O-N 3.26Å; T335-I339 VanDerWaalsContact O-N 3.08Å; T336-I339 PolarHBondContact O-N 3.23Å; I339-S342 PolarHBondContact O-N 3.29Å; I339-S342 PolarHBondContact O-OG 3.02Å; I339-Y343 WeakPolarHBondContact O-CB 3.5Å; I339-Y343 PolarHBondContact O-N 3.42Å
340	W	76.9	Confident	72.6	Confident	127 Å²	127	72.2 Å²	72.2	48%	0.481	35%	0.347	S	S	.	.	H	α-helix	trans	-59.5	-49.4	173.6	176.7	87.7	0	0	0	110.3	T336 Y337 S342 Y343 Y344	T336-W340 VanDerWaalsContact O-CB 3.28Å; T336-W340 WeakPolarHBondContact O-CB 3.42Å; T336-W340 PolarHBondContact O-N 3.38Å; Y337-W340 HydrophobicContact CD2-CE3 4.01Å; Y337-W340 HydrophobicContact CD2-CZ3 4.41Å; Y337-W340 AromaticContact CE2-CE3 3.81Å; Y337-W340 HydrophobicContact CE2-CE3 3.81Å; Y337-W340 AromaticContact CE2-CZ3 3.77Å; Y337-W340 HydrophobicContact CE2-CZ3 3.77Å; Y337-W340 PolarHBondContact O-N 2.86Å; W340-S342 VanDerWaalsContact C-N 3.34Å; W340-S342 PolarHBondContact O-N 3.11Å; W340-Y343 PolarHBondContact O-N 3.46Å; W340-Y343 VanDerWaalsContact O-N 3.16Å; W340-Y344 AromaticContact CD1-CD2 3.36Å; W340-Y344 AromaticContact CD1-CE2 3.21Å; W340-Y344 AromaticContact CD2-CD2 3.91Å; W340-Y344 HydrophobicContact CD2-CD2 3.91Å; W340-Y344 HydrophobicContact CD2-CE2 4.47Å; W340-Y344 AromaticContact CE2-CD2 3.5Å; W340-Y344 VanDerWaalsContact CE2-CD2 3.5Å; W340-Y344 AromaticContact CE2-CE2 3.87Å; W340-Y344 AromaticContact CG-CD2 3.81Å; W340-Y344 HydrophobicContact CG-CD2 3.81Å; W340-Y344 HydrophobicContact CG-CE2 4.09Å; W340-Y344 HydrophobicContact CZ2-CD2 4.15Å; W340-Y344 HydrophobicContact CZ2-CG 4.38Å; W340-Y344 AromaticContact NE1-CD2 3.14Å; W340-Y344 AromaticContact NE1-CE2 3.03Å; W340-Y344 AromaticContact NE1-CZ 3.89Å; W340-Y344 VanDerWaalsContact O-CD2 3.28Å; W340-Y344 WeakPolarHBondContact O-CD2 3.41Å; W340-Y344 PolarHBondContact O-N 3.42Å
341	A	74	Confident	70.7	Confident	2 Å²	2	74 Å²	74	2%	0.017	35%	0.348	C	S	.	.	H	α-helix	trans	-61.1	-41.1	177.5	0	0	0	0	0	111.9	Y337 Y343 L345 L373	Y337-A341 HydrophobicContact CE1-CB 4.5Å; Y337-A341 VanDerWaalsContact O-CB 3.24Å; Y337-A341 WeakPolarHBondContact O-CB 3.34Å; Y337-A341 PolarHBondContact O-N 3.46Å; A341-Y343 VanDerWaalsContact C-N 3.27Å; A341-Y343 PolarHBondContact O-N 2.91Å; A341-L345 HydrophobicContact CB-CD1 4.12Å; A341-L345 WeakPolarHBondContact O-CB 3.48Å; A341-L345 WeakPolarHBondContact O-CG 3.31Å; A341-L345 PolarHBondContact O-N 2.95Å; A341-L373 HydrophobicContact CB-CD2 3.71Å
342	S	67.4	Low	68.8	Low	9 Å²	9	76.3 Å²	76.3	6%	0.063	36%	0.361	C	S	.	.	H	α-helix	trans	-62.2	-36.7	177.3	77.2	0	0	0	0	112.3	G338 I339 W340	G338-S342 WeakPolarHBondContact O-CB 3.48Å; G338-S342 PolarHBondContact O-N 3.4Å; I339-S342 PolarHBondContact O-N 3.29Å; I339-S342 PolarHBondContact O-OG 3.02Å; W340-S342 VanDerWaalsContact C-N 3.34Å; W340-S342 PolarHBondContact O-N 3.11Å
343	Y	66.1	Low	67	Low	142 Å²	142	73.9 Å²	73.9	56%	0.557	35%	0.35	S	S	*	.	H	α-helix	trans	-74.4	-45.5	179.6	-177.6	-95.5	0	0	0	112.9	I339 W340 A341	I339-Y343 WeakPolarHBondContact O-CB 3.5Å; I339-Y343 PolarHBondContact O-N 3.42Å; W340-Y343 PolarHBondContact O-N 3.46Å; W340-Y343 VanDerWaalsContact O-N 3.16Å; A341-Y343 VanDerWaalsContact C-N 3.27Å; A341-Y343 PolarHBondContact O-N 2.91Å
344	Y	73.8	Confident	65.3	Low	147 Å²	147	67.9 Å²	67.9	58%	0.576	33%	0.327	S	S	*	.	H	α-helix	trans	-86.4	-22.6	-172.3	-78.4	-79.6	0	0	0	114.3	W340	W340-Y344 AromaticContact CD1-CD2 3.36Å; W340-Y344 AromaticContact CD1-CE2 3.21Å; W340-Y344 AromaticContact CD2-CD2 3.91Å; W340-Y344 HydrophobicContact CD2-CD2 3.91Å; W340-Y344 HydrophobicContact CD2-CE2 4.47Å; W340-Y344 AromaticContact CE2-CD2 3.5Å; W340-Y344 VanDerWaalsContact CE2-CD2 3.5Å; W340-Y344 AromaticContact CE2-CE2 3.87Å; W340-Y344 AromaticContact CG-CD2 3.81Å; W340-Y344 HydrophobicContact CG-CD2 3.81Å; W340-Y344 HydrophobicContact CG-CE2 4.09Å; W340-Y344 HydrophobicContact CZ2-CD2 4.15Å; W340-Y344 HydrophobicContact CZ2-CG 4.38Å; W340-Y344 AromaticContact NE1-CD2 3.14Å; W340-Y344 AromaticContact NE1-CE2 3.03Å; W340-Y344 AromaticContact NE1-CZ 3.89Å; W340-Y344 VanDerWaalsContact O-CD2 3.28Å; W340-Y344 WeakPolarHBondContact O-CD2 3.41Å; W340-Y344 PolarHBondContact O-N 3.42Å
345	L	69.2	Low	64.1	Low	107 Å²	107	66.5 Å²	66.5	56%	0.56	32%	0.318	S	S	*	.	T	Hydrogen-bonded Turn	trans	-100.7	10.6	-178.1	-59.3	173.8	0	0	0	112.7	A341 L347	A341-L345 HydrophobicContact CB-CD1 4.12Å; A341-L345 WeakPolarHBondContact O-CB 3.48Å; A341-L345 WeakPolarHBondContact O-CG 3.31Å; A341-L345 PolarHBondContact O-N 2.95Å; L345-L347 HydrophobicContact CB-CD1 3.95Å; L345-L347 HydrophobicContact CB-CD2 4.23Å; L345-L347 HydrophobicContact CB-CG 3.69Å; L345-L347 HydrophobicContact CD1-CD1 4.14Å; L345-L347 PolarHBondContact O-N 3.43Å; L345-L347 VanDerWaalsContact O-N 3.1Å
346	D	60.7	Low	62.8	Low	130 Å²	130	66.6 Å²	66.6	70%	0.695	32%	0.319	S	S	*	.	T	Hydrogen-bonded Turn	trans	44.9	43.1	-177.6	-75.2	-34	0	0	0	113.1	N348	D346-N348 PolarHBondContact O-N 3.04Å
347	L	56.9	Low	61.5	Low	38 Å²	38	65.9 Å²	65.9	20%	0.199	31%	0.312	C	S	.	.			trans	-77.7	34	-177.6	-65.5	176.1	0	0	0	112.2	L345 L367 A369	L345-L347 HydrophobicContact CB-CD1 3.95Å; L345-L347 HydrophobicContact CB-CD2 4.23Å; L345-L347 HydrophobicContact CB-CG 3.69Å; L345-L347 HydrophobicContact CD1-CD1 4.14Å; L345-L347 PolarHBondContact O-N 3.43Å; L345-L347 VanDerWaalsContact O-N 3.1Å; L347-L367 VanDerWaalsContact C-CD1 3.47Å; L347-L367 HydrophobicContact CB-CD2 3.65Å; L347-L367 HydrophobicContact CD2-CD2 4.19Å; L347-L367 HydrophobicContact CG-CD2 4.37Å; L347-L367 WeakPolarHBondContact O-CD1 3.42Å; L347-L367 WeakPolarHBondContact O-CD2 3.42Å; L347-L367 WeakPolarHBondContact O-CG 3.37Å; L347-A369 HydrophobicContact CD1-CB 4.11Å; L347-A369 HydrophobicContact CD2-CB 3.86Å
348	N	50.4	Low	60.3	Low	56 Å²	56	60.6 Å²	60.6	30%	0.299	29%	0.292	S	S	.	.			trans	-94.6	118	177.9	-63.2	-34.1	0	0	0	109	Y68 D346	Y68-N348 VanDerWaalsContact OH-CB 3.32Å; Y68-N348 WeakPolarHBondContact OH-CB 3.42Å; Y68-N348 PolarHBondContact OH-ND2 3.43Å; Y68-N348 VanDerWaalsContact OH-ND2 3.15Å; D346-N348 PolarHBondContact O-N 3.04Å
349	S	46.8	Very low	59.6	Low	43 Å²	43	61 Å²	61	30%	0.301	30%	0.295	S	S	.	.			trans	-101.1	162.5	178.6	65.4	0	0	0	0	112.4	W351 L367	S349-W351 PolarHBondContact O-N 2.78Å; S349-L367 VanDerWaalsContact CB-CD1 3.46Å
350	I	46.8	Very low	59	Low	140 Å²	140	59.2 Å²	59.2	72%	0.718	29%	0.286	S	S	*	.			trans	-29.9	106.1	164	-56.2	168.7	0	0	0	110.3
351	W	50.2	Low	57.6	Low	115 Å²	115	54.2 Å²	54.2	44%	0.436	27%	0.274	S	S	.	.			trans	-80.4	122.8	-172.5	-167.7	67.1	0	0	0	108.5	I66 S349 P353 I357	I66-W351 HydrophobicContact CD1-CE3 3.65Å; I66-W351 HydrophobicContact CD1-CH2 4.28Å; I66-W351 HydrophobicContact CD1-CZ3 3.18Å; S349-W351 PolarHBondContact O-N 2.78Å; W351-P353 HydrophobicContact CD2-CB 4.36Å; W351-P353 HydrophobicContact CE3-CB 3.39Å; W351-P353 HydrophobicContact CE3-CG 4.48Å; W351-P353 HydrophobicContact CH2-CB 4Å; W351-P353 HydrophobicContact CZ3-CB 3.13Å; W351-P353 WeakPolarHBondContact O-CD 3.37Å; W351-I357 HydrophobicContact CH2-CD1 4.29Å; W351-I357 HydrophobicContact CH2-CG1 3.7Å; W351-I357 HydrophobicContact CZ2-CG1 4.28Å
352	N	51.3	Low	56.6	Low	51 Å²	51	55.6 Å²	55.6	27%	0.273	28%	0.281	S	S	.	.			trans	-76.8	106.7	159.9	179.8	-5.8	0	0	0	106.8	A354 Y355 G356 C441	N352-A354 PolarHBondContact O-N 2.82Å; N352-A354 PolarHBondContact OD1-N 2.94Å; N352-Y355 PolarHBondContact O-N 2.81Å; N352-G356 PolarHBondContact O-N 3.4Å; N352-C441 PolarHBondContact ND2-O 2.76Å
353	P	50.2	Low	55.5	Low	27 Å²	27	57.1 Å²	57.1	18%	0.175	29%	0.288	C	S	.	.	H	α-helix	trans	-60.7	-35	-172.3	25.1	-36.2	0	0	0	113.2	I66 W351 G356 I357	I66-P353 HydrophobicContact CD1-CB 4.01Å; W351-P353 HydrophobicContact CD2-CB 4.36Å; W351-P353 HydrophobicContact CE3-CB 3.39Å; W351-P353 HydrophobicContact CE3-CG 4.48Å; W351-P353 HydrophobicContact CH2-CB 4Å; W351-P353 HydrophobicContact CZ3-CB 3.13Å; W351-P353 WeakPolarHBondContact O-CD 3.37Å; P353-G356 PolarHBondContact O-N 2.76Å; P353-I357 WeakPolarHBondContact O-CB 3.3Å; P353-I357 WeakPolarHBondContact O-CD1 3.31Å; P353-I357 WeakPolarHBondContact O-CG1 3.3Å; P353-I357 PolarHBondContact O-N 3.2Å
354	A	51.8	Low	54.6	Low	19 Å²	19	50.9 Å²	50.9	16%	0.157	27%	0.267	C	S	.	.	H	α-helix	trans	-67.6	-37.9	177.7	0	0	0	0	0	111.8	N352 I358	N352-A354 PolarHBondContact O-N 2.82Å; N352-A354 PolarHBondContact OD1-N 2.94Å; A354-I358 VanDerWaalsContact O-CD1 3.25Å; A354-I358 WeakPolarHBondContact O-CD1 3.34Å; A354-I358 VanDerWaalsContact O-CG1 3.23Å; A354-I358 WeakPolarHBondContact O-CG1 3.45Å
355	Y	58.6	Low	53.3	Low	6 Å²	6	44.2 Å²	44.2	2%	0.024	24%	0.243	C	C	.	.	H	α-helix	trans	-69.3	-49	175.7	-167.2	-99.2	0	0	0	110.3	N352 I357 I358 T359 S437 N438 W446	N352-Y355 PolarHBondContact O-N 2.81Å; Y355-I357 PolarHBondContact O-N 3.04Å; Y355-I358 PolarHBondContact O-N 2.94Å; Y355-T359 HydrophobicContact CD1-CG2 4.13Å; Y355-T359 HydrophobicContact CE1-CG2 3.86Å; Y355-T359 HydrophobicContact CE2-CG2 4.33Å; Y355-T359 HydrophobicContact CG-CG2 4.47Å; Y355-T359 WeakPolarHBondContact O-CG2 3.38Å; Y355-T359 PolarHBondContact O-N 2.91Å; Y355-T359 PolarHBondContact O-OG1 2.81Å; Y355-T359 VanDerWaalsContact O-OG1 3.05Å; Y355-S437 PolarHBondContact OH-O 3.36Å; Y355-S437 PolarHBondContact OH-OG 3.01Å; Y355-N438 PolarHBondContact OH-OD1 2.96Å; Y355-W446 HydrophobicContact CE2-CB 3.87Å; Y355-W446 HydrophobicContact CE2-CG 4.35Å
356	G	55.6	Low	52.6	Low	3 Å²	3	41.2 Å²	41.2	3%	0.031	23%	0.23	C	C	.	.	H	α-helix	trans	-61.9	-41.3	-178.7	0	0	0	0	0	114	N352 P353 I358 T359 C360 G361	N352-G356 PolarHBondContact O-N 3.4Å; P353-G356 PolarHBondContact O-N 2.76Å; G356-I358 VanDerWaalsContact C-N 3.28Å; G356-I358 PolarHBondContact O-N 3.37Å; G356-T359 PolarHBondContact O-N 3.4Å; G356-C360 CarbonylContact O-C 3.06Å; G356-C360 PolarHBondContact O-N 2.88Å; G356-C360 VanDerWaalsContact O-N 3.14Å; G356-G361 PolarHBondContact O-N 3.36Å
357	I	53.7	Low	52.3	Low	52 Å²	52	36.3 Å²	36.3	27%	0.267	20%	0.204	S	C	.	.	H	α-helix	trans	-61.1	-41.4	176.3	-68.3	164.4	0	0	0	110.8	I64 W351 P353 Y355	I64-I357 HydrophobicContact CD1-CD1 4.03Å; W351-I357 HydrophobicContact CH2-CD1 4.29Å; W351-I357 HydrophobicContact CH2-CG1 3.7Å; W351-I357 HydrophobicContact CZ2-CG1 4.28Å; P353-I357 WeakPolarHBondContact O-CB 3.3Å; P353-I357 WeakPolarHBondContact O-CD1 3.31Å; P353-I357 WeakPolarHBondContact O-CG1 3.3Å; P353-I357 PolarHBondContact O-N 3.2Å; Y355-I357 PolarHBondContact O-N 3.04Å
358	I	58.1	Low	52.3	Low	12 Å²	12	38 Å²	38	6%	0.062	22%	0.216	C	C	.	.	H	α-helix	trans	-73.1	-32.1	-177.7	-65.7	170.7	0	0	0	111.4	A142 A354 Y355 G356 T443 W446	A142-I358 WeakPolarHBondContact CA-O 3.39Å; A142-I358 VanDerWaalsContact CB-O 3.26Å; A142-I358 WeakPolarHBondContact CB-O 3.43Å; A354-I358 VanDerWaalsContact O-CD1 3.25Å; A354-I358 WeakPolarHBondContact O-CD1 3.34Å; A354-I358 VanDerWaalsContact O-CG1 3.23Å; A354-I358 WeakPolarHBondContact O-CG1 3.45Å; Y355-I358 PolarHBondContact O-N 2.94Å; G356-I358 VanDerWaalsContact C-N 3.28Å; G356-I358 PolarHBondContact O-N 3.37Å; I358-T443 HydrophobicContact CD1-CG2 3.3Å; I358-W446 HydrophobicContact CG2-CD2 4.04Å; I358-W446 HydrophobicContact CG2-CE3 3.46Å; I358-W446 VanDerWaalsContact CG2-CE3 3.46Å; I358-W446 HydrophobicContact CG2-CH2 3.63Å; I358-W446 HydrophobicContact CG2-CZ2 4.17Å; I358-W446 HydrophobicContact CG2-CZ3 3.24Å
359	T	61.3	Low	52.7	Low	10 Å²	10	37.1 Å²	37.1	6%	0.061	22%	0.216	C	C	.	.	T	Hydrogen-bonded Turn	trans	-101.6	17.8	-176.6	67.3	0	0	0	0	114.1	Y355 G356 G361 N362 W446	Y355-T359 HydrophobicContact CD1-CG2 4.13Å; Y355-T359 HydrophobicContact CE1-CG2 3.86Å; Y355-T359 HydrophobicContact CE2-CG2 4.33Å; Y355-T359 HydrophobicContact CG-CG2 4.47Å; Y355-T359 WeakPolarHBondContact O-CG2 3.38Å; Y355-T359 PolarHBondContact O-N 2.91Å; Y355-T359 PolarHBondContact O-OG1 2.81Å; Y355-T359 VanDerWaalsContact O-OG1 3.05Å; G356-T359 PolarHBondContact O-N 3.4Å; T359-G361 PolarHBondContact O-N 2.84Å; T359-N362 PolarHBondContact O-N 3.46Å; T359-N362 VanDerWaalsContact O-N 3.07Å; T359-W446 HydrophobicContact CG2-CD2 4.2Å; T359-W446 HydrophobicContact CG2-CG 4.07Å
360	C	58.6	Low	53.4	Low	7 Å²	7	35.3 Å²	35.3	5%	0.047	20%	0.203	C	C	.	.	T	Hydrogen-bonded Turn	trans	46.9	47.1	-171.6	-149	0	0	0	0	112.1	S141 P145 C169 G356 N362	S141-C360 VanDerWaalsContact O-CB 3.25Å; S141-C360 WeakPolarHBondContact O-CB 3.45Å; P145-C360 HydrophobicContact CG-CB 3.93Å; P145-C360 WeakPolarHBondContact CG-SG 3.35Å; C169-C360 WeakPolarHBondContact CA-SG 2.93Å; C169-C360 HydrophobicContact CB-CB 3.94Å; C169-C360 WeakPolarHBondContact CB-O 3.47Å; C169-C360 WeakPolarHBondContact CB-SG 3.17Å; C169-C360 WeakPolarHBondContact SG-CA 3.3Å; C169-C360 WeakPolarHBondContact SG-CB 3.42Å; C169-C360 PolarHBondContact SG-O 2.84Å; C169-C360 CovalentContact SG-SG 2.05Å; C169-C360 PolarHBondContact SG-SG 3.31Å; G356-C360 CarbonylContact O-C 3.06Å; G356-C360 PolarHBondContact O-N 2.88Å; G356-C360 VanDerWaalsContact O-N 3.14Å; C360-N362 PolarHBondContact O-N 2.82Å
361	G	49.2	Very low	54.2	Low	22 Å²	22	29 Å²	29	23%	0.227	17%	0.17	C	C	.	.	T	Hydrogen-bonded Turn	trans	53.3	28.8	178.4	0	0	0	0	0	114.5	G356 T359 L363	G356-G361 PolarHBondContact O-N 3.36Å; T359-G361 PolarHBondContact O-N 2.84Å; G361-L363 WeakPolarHBondContact O-CA 3.33Å; G361-L363 WeakPolarHBondContact O-CG 3.44Å; G361-L363 PolarHBondContact O-N 3.21Å
362	N	51.8	Low	55.1	Low	32 Å²	32	30.8 Å²	30.8	17%	0.171	18%	0.177	C	C	.	.			trans	-28.9	99.7	173	-170.5	-8.2	0	0	0	108.8	D173 T359 C360 G364 G365	D173-N362 PolarHBondContact OD1-OD1 3.12Å; D173-N362 PolarHBondContact OD2-OD1 3.49Å; T359-N362 PolarHBondContact O-N 3.46Å; T359-N362 VanDerWaalsContact O-N 3.07Å; C360-N362 PolarHBondContact O-N 2.82Å; N362-G364 PolarHBondContact O-N 3.06Å; N362-G365 PolarHBondContact O-N 3.44Å
363	L	44.3	Very low	56	Low	40 Å²	40	30.8 Å²	30.8	21%	0.209	18%	0.177	C	C	.	.	T	Hydrogen-bonded Turn	trans	-73	101	-152.8	-97.1	140.4	0	0	0	106.3	R170 D173 G361 Y370	R170-L363 HydrophobicContact CB-CD1 4.33Å; R170-L363 HydrophobicContact CG-CD1 3.34Å; D173-L363 PolarHBondContact OD2-N 2.94Å; G361-L363 WeakPolarHBondContact O-CA 3.33Å; G361-L363 WeakPolarHBondContact O-CG 3.44Å; G361-L363 PolarHBondContact O-N 3.21Å; L363-Y370 WeakPolarHBondContact O-CD1 3.33Å; L363-Y370 WeakPolarHBondContact O-CE1 3.17Å; L363-Y370 VanDerWaalsContact O-CG 3.28Å
364	G	46.9	Very low	57.1	Low	12 Å²	12	29.6 Å²	29.6	12%	0.124	17%	0.169	C	C	.	.	T	Hydrogen-bonded Turn	trans	104.6	16.5	-175	0	0	0	0	0	114.8	N362 C366 L367	N362-G364 PolarHBondContact O-N 3.06Å; G364-C366 PolarHBondContact O-N 3.28Å; G364-L367 PolarHBondContact O-N 3.47Å
365	G	47.6	Very low	58.4	Low	6 Å²	6	29.5 Å²	29.5	6%	0.062	17%	0.165	C	C	.	.	T	Hydrogen-bonded Turn	trans	-45.6	-34.1	171	0	0	0	0	0	113.4	N362 Q371 N438 C441	N362-G365 PolarHBondContact O-N 3.44Å; G365-Q371 PolarHBondContact O-NE2 3.48Å; G365-N438 CarbonylContact O-C 3.59Å; G365-N438 VanDerWaalsContact O-CA 3.29Å; G365-N438 WeakPolarHBondContact O-CA 3.4Å; G365-N438 WeakPolarHBondContact O-CB 3.44Å; G365-C441 PolarHBondContact O-SG 2.92Å; G365-C441 VanDerWaalsContact O-SG 3.38Å
366	C	53	Low	59.6	Low	44 Å²	44	33.8 Å²	33.8	30%	0.297	19%	0.188	S	C	.	.	T	Hydrogen-bonded Turn	trans	-107.9	-5.9	176.8	-42.9	0	0	0	0	114.6	G364 C441	G364-C366 PolarHBondContact O-N 3.28Å; C366-C441 WeakPolarHBondContact CA-SG 2.97Å; C366-C441 HydrophobicContact CB-CB 4.07Å; C366-C441 WeakPolarHBondContact CB-SG 3.46Å; C366-C441 PolarHBondContact N-SG 3.43Å; C366-C441 WeakPolarHBondContact SG-CB 3.09Å; C366-C441 CovalentContact SG-SG 2Å; C366-C441 PolarHBondContact SG-SG 3.47Å
367	L	54.3	Low	61	Low	27 Å²	27	35.5 Å²	35.5	14%	0.141	20%	0.198	C	C	.	.			trans	-96.6	114.5	-170.7	-168.5	129.6	0	0	0	109.9	L347 S349 G364 A369 Y370 Q371	L347-L367 VanDerWaalsContact C-CD1 3.47Å; L347-L367 HydrophobicContact CB-CD2 3.65Å; L347-L367 HydrophobicContact CD2-CD2 4.19Å; L347-L367 HydrophobicContact CG-CD2 4.37Å; L347-L367 WeakPolarHBondContact O-CD1 3.42Å; L347-L367 WeakPolarHBondContact O-CD2 3.42Å; L347-L367 WeakPolarHBondContact O-CG 3.37Å; S349-L367 VanDerWaalsContact CB-CD1 3.46Å; G364-L367 PolarHBondContact O-N 3.47Å; L367-A369 VanDerWaalsContact C-N 3.26Å; L367-A369 HydrophobicContact CD2-CB 3.65Å; L367-A369 PolarHBondContact O-N 2.99Å; L367-Y370 PolarHBondContact O-N 2.9Å; L367-Q371 WeakPolarHBondContact O-CG 3.39Å; L367-Q371 PolarHBondContact O-N 2.82Å; L367-Q371 VanDerWaalsContact O-N 3.13Å
368	T	57.7	Low	62.5	Low	74 Å²	74	33.6 Å²	33.6	45%	0.454	19%	0.189	S	C	.	.	H	α-helix	trans	-49.7	-45.3	-177.8	49.9	0	0	0	0	111.9	Q371 W372	T368-Q371 WeakPolarHBondContact O-CB 3.27Å; T368-Q371 PolarHBondContact O-N 3.3Å; T368-W372 VanDerWaalsContact C-CD1 3.42Å; T368-W372 WeakPolarHBondContact O-CB 3.31Å; T368-W372 PolarHBondContact O-N 3.27Å
369	A	58.4	Low	63.9	Low	37 Å²	37	34.6 Å²	34.6	31%	0.306	20%	0.199	S	C	.	.	H	α-helix	trans	-65.3	-43.3	-175.1	0	0	0	0	0	114.7	L347 L367 W372 L373	L347-A369 HydrophobicContact CD1-CB 4.11Å; L347-A369 HydrophobicContact CD2-CB 3.86Å; L367-A369 VanDerWaalsContact C-N 3.26Å; L367-A369 HydrophobicContact CD2-CB 3.65Å; L367-A369 PolarHBondContact O-N 2.99Å; A369-W372 PolarHBondContact O-N 2.86Å; A369-L373 PolarHBondContact O-N 2.98Å
370	Y	61.7	Low	65.4	Low	6 Å²	6	40.4 Å²	40.4	2%	0.024	22%	0.223	C	C	.	.	H	α-helix	trans	-67.3	-40.9	175.3	-175.8	-93.9	0	0	0	110.8	G338 L363 L367 W372 L373 M374	G338-Y370 WeakPolarHBondContact O-CE2 3.3Å; L363-Y370 WeakPolarHBondContact O-CD1 3.33Å; L363-Y370 WeakPolarHBondContact O-CE1 3.17Å; L363-Y370 VanDerWaalsContact O-CG 3.28Å; L367-Y370 PolarHBondContact O-N 2.9Å; Y370-W372 VanDerWaalsContact C-N 3.35Å; Y370-W372 PolarHBondContact O-N 3.08Å; Y370-L373 PolarHBondContact O-N 3.21Å; Y370-M374 HydrophobicContact CE1-CG 3.98Å; Y370-M374 HydrophobicContact CE2-CE 4.05Å; Y370-M374 HydrophobicContact CE2-CG 4.47Å; Y370-M374 PolarHBondContact O-N 3.32Å; Y370-M374 VanDerWaalsContact O-N 3.16Å; Y370-M374 WeakPolarHBondContact OH-CE 3.42Å
371	Q	64.9	Low	67	Low	6 Å²	6	40.9 Å²	40.9	3%	0.028	23%	0.225	C	C	.	.	H	α-helix	trans	-57.3	-48.2	172.7	-69.2	177.6	-8.5	0	0	110.9	G365 L367 T368 L373 M374 H375 N438	G365-Q371 PolarHBondContact O-NE2 3.48Å; L367-Q371 WeakPolarHBondContact O-CG 3.39Å; L367-Q371 PolarHBondContact O-N 2.82Å; L367-Q371 VanDerWaalsContact O-N 3.13Å; T368-Q371 WeakPolarHBondContact O-CB 3.27Å; T368-Q371 PolarHBondContact O-N 3.3Å; Q371-L373 VanDerWaalsContact C-N 3.32Å; Q371-L373 PolarHBondContact O-N 2.85Å; Q371-M374 PolarHBondContact O-N 2.88Å; Q371-H375 WeakPolarHBondContact CA-ND1 3.29Å; Q371-H375 WeakPolarHBondContact O-CA 3.06Å; Q371-H375 WeakPolarHBondContact O-CB 3.48Å; Q371-H375 VanDerWaalsContact O-CG 3.25Å; Q371-H375 PolarHBondContact O-N 3.46Å; Q371-H375 PolarHBondContact O-ND1 2.96Å; Q371-N438 PolarHBondContact NE2-O 3Å
372	W	68.6	Low	69	Low	153 Å²	153	40.1 Å²	40.1	58%	0.58	22%	0.217	S	C	*	.	H	α-helix	trans	-58.8	-44.6	178.5	-75.6	114.3	0	0	0	111.4	T368 A369 Y370 M374 I376	T368-W372 VanDerWaalsContact C-CD1 3.42Å; T368-W372 WeakPolarHBondContact O-CB 3.31Å; T368-W372 PolarHBondContact O-N 3.27Å; A369-W372 PolarHBondContact O-N 2.86Å; Y370-W372 VanDerWaalsContact C-N 3.35Å; Y370-W372 PolarHBondContact O-N 3.08Å; W372-M374 VanDerWaalsContact C-N 3.34Å; W372-M374 PolarHBondContact O-N 3.31Å; W372-I376 HydrophobicContact CB-CD1 4.08Å; W372-I376 HydrophobicContact CE3-CD1 3.83Å; W372-I376 HydrophobicContact CE3-CG1 3.78Å; W372-I376 HydrophobicContact CZ3-CG1 4.48Å; W372-I376 WeakPolarHBondContact O-CB 3.32Å; W372-I376 VanDerWaalsContact O-CD1 3.29Å; W372-I376 WeakPolarHBondContact O-CD1 3.31Å; W372-I376 WeakPolarHBondContact O-CG1 3.03Å; W372-I376 PolarHBondContact O-N 3.26Å
373	L	70.7	Confident	70.9	Confident	51 Å²	51	45.1 Å²	45.1	27%	0.267	24%	0.237	S	C	.	.	H	α-helix	trans	-63.8	-37.5	-176.4	-170.9	57.8	0	0	0	113.3	Y337 G338 A341 A369 Y370 Q371 P377	Y337-L373 HydrophobicContact CD1-CD1 3.92Å; Y337-L373 HydrophobicContact CD1-CD2 3.89Å; Y337-L373 HydrophobicContact CD1-CG 4.31Å; Y337-L373 HydrophobicContact CE1-CD1 3.75Å; Y337-L373 HydrophobicContact CE1-CD2 3.89Å; Y337-L373 HydrophobicContact CE1-CG 4.42Å; G338-L373 VanDerWaalsContact CA-CD2 3.48Å; A341-L373 HydrophobicContact CB-CD2 3.71Å; A369-L373 PolarHBondContact O-N 2.98Å; Y370-L373 PolarHBondContact O-N 3.21Å; Q371-L373 VanDerWaalsContact C-N 3.32Å; Q371-L373 PolarHBondContact O-N 2.85Å; L373-P377 WeakPolarHBondContact O-CD 3.29Å
374	M	72.2	Confident	73.3	Confident	3 Å²	3	44.4 Å²	44.4	2%	0.015	23%	0.234	C	C	.	.	H	α-helix	trans	-90.5	-33.8	178.7	-65.7	-58.4	-170.1	0	0	113.8	Y370 Q371 W372	Y370-M374 HydrophobicContact CE1-CG 3.98Å; Y370-M374 HydrophobicContact CE2-CE 4.05Å; Y370-M374 HydrophobicContact CE2-CG 4.47Å; Y370-M374 PolarHBondContact O-N 3.32Å; Y370-M374 VanDerWaalsContact O-N 3.16Å; Y370-M374 WeakPolarHBondContact OH-CE 3.42Å; Q371-M374 PolarHBondContact O-N 2.88Å; W372-M374 VanDerWaalsContact C-N 3.34Å; W372-M374 PolarHBondContact O-N 3.31Å
375	H	78.8	Confident	75.5	Confident	17 Å²	17	44 Å²	44	8%	0.079	23%	0.229	C	C	.	.	H	α-helix	trans	-82.5	-25.8	-177.2	-66	71.4	0	0	0	112.5	Q371 L378 A379 W431 F435	Q371-H375 WeakPolarHBondContact CA-ND1 3.29Å; Q371-H375 WeakPolarHBondContact O-CA 3.06Å; Q371-H375 WeakPolarHBondContact O-CB 3.48Å; Q371-H375 VanDerWaalsContact O-CG 3.25Å; Q371-H375 PolarHBondContact O-N 3.46Å; Q371-H375 PolarHBondContact O-ND1 2.96Å; H375-L378 PolarHBondContact O-N 3.09Å; H375-A379 WeakPolarHBondContact O-CB 3.47Å; H375-A379 PolarHBondContact O-N 3.44Å; H375-W431 HydrophobicContact CB-CZ2 4.31Å; H375-W431 AromaticContact CD2-NE1 3.57Å; H375-F435 HydrophobicContact CB-CD2 4.46Å; H375-F435 AromaticContact CD2-CD2 3.44Å; H375-F435 VanDerWaalsContact CD2-CD2 3.44Å; H375-F435 WeakPolarHBondContact CD2-CD2 3.47Å; H375-F435 AromaticContact CG-CD2 4Å; H375-F435 AromaticContact NE2-CD2 3.91Å
376	I	83.6	Confident	77.6	Confident	95 Å²	95	46.8 Å²	46.8	49%	0.487	24%	0.242	S	C	.	.	H	α-helix	trans	-61.5	-52.6	176.1	-72.5	165.8	0	0	0	111.5	W372 L378 A379 F380	W372-I376 HydrophobicContact CB-CD1 4.08Å; W372-I376 HydrophobicContact CE3-CD1 3.83Å; W372-I376 HydrophobicContact CE3-CG1 3.78Å; W372-I376 HydrophobicContact CZ3-CG1 4.48Å; W372-I376 WeakPolarHBondContact O-CB 3.32Å; W372-I376 VanDerWaalsContact O-CD1 3.29Å; W372-I376 WeakPolarHBondContact O-CD1 3.31Å; W372-I376 WeakPolarHBondContact O-CG1 3.03Å; W372-I376 PolarHBondContact O-N 3.26Å; I376-L378 PolarHBondContact O-N 3.24Å; I376-A379 PolarHBondContact O-N 2.92Å; I376-F380 WeakPolarHBondContact O-CB 3.36Å; I376-F380 PolarHBondContact O-N 2.96Å
377	P	85.1	Confident	79.6	Confident	40 Å²	40	47.3 Å²	47.3	26%	0.26	24%	0.244	S	C	.	.	H	α-helix	trans	-57.1	-38.8	176.1	-25.5	34.2	0	0	0	112.2	L181 P334 L373 F380 L381	L181-P377 HydrophobicContact CD2-CB 4.09Å; P334-P377 HydrophobicContact CB-CG 4.48Å; L373-P377 WeakPolarHBondContact O-CD 3.29Å; P377-F380 PolarHBondContact O-N 3.23Å; P377-L381 VanDerWaalsContact O-CG 3.31Å; P377-L381 WeakPolarHBondContact O-CG 3.49Å; P377-L381 PolarHBondContact O-N 3.12Å
378	L	86.6	Confident	81.4	Confident	12 Å²	12	46.8 Å²	46.8	6%	0.063	24%	0.241	C	C	.	.	H	α-helix	trans	-68.9	-45	-179.4	-161	55.9	0	0	0	112.3	I180 L181 Y184 H375 I376 F380 L381 C382 W431	I180-L378 HydrophobicContact CG1-CD1 4.36Å; I180-L378 HydrophobicContact CG1-CD2 4.12Å; I180-L378 HydrophobicContact CG2-CD2 4.32Å; L181-L378 HydrophobicContact CD2-CB 4.49Å; L181-L378 HydrophobicContact CD2-CD1 4.15Å; Y184-L378 HydrophobicContact CD1-CD1 4.15Å; Y184-L378 HydrophobicContact CD2-CD1 3.16Å; Y184-L378 HydrophobicContact CD2-CG 4.21Å; Y184-L378 HydrophobicContact CE1-CD1 4.47Å; Y184-L378 HydrophobicContact CE2-CD1 3.53Å; Y184-L378 HydrophobicContact CE2-CD2 4.47Å; Y184-L378 HydrophobicContact CE2-CG 4.12Å; Y184-L378 HydrophobicContact CG-CD1 3.47Å; Y184-L378 VanDerWaalsContact CG-CD1 3.47Å; H375-L378 PolarHBondContact O-N 3.09Å; I376-L378 PolarHBondContact O-N 3.24Å; L378-F380 VanDerWaalsContact C-N 3.32Å; L378-F380 PolarHBondContact O-N 3.43Å; L378-L381 PolarHBondContact O-N 3.49Å; L378-C382 VanDerWaalsContact O-CB 3.3Å; L378-C382 WeakPolarHBondContact O-CB 3.32Å; L378-C382 PolarHBondContact O-N 2.91Å; L378-W431 HydrophobicContact CD2-CG 4.29Å; L378-W431 HydrophobicContact CG-CG 4.44Å
379	A	87.5	Confident	83	Confident	33 Å²	33	44.3 Å²	44.3	27%	0.273	23%	0.225	S	C	.	.	H	α-helix	trans	-61.5	-41.3	174.8	0	0	0	0	0	111.1	H375 I376 C382 F383 W431	H375-A379 WeakPolarHBondContact O-CB 3.47Å; H375-A379 PolarHBondContact O-N 3.44Å; I376-A379 PolarHBondContact O-N 2.92Å; A379-C382 WeakPolarHBondContact O-CB 3.18Å; A379-C382 PolarHBondContact O-N 3.45Å; A379-F383 WeakPolarHBondContact O-CB 3.37Å; A379-F383 PolarHBondContact O-N 3.32Å; A379-W431 HydrophobicContact CB-CH2 3.77Å; A379-W431 HydrophobicContact CB-CZ2 3.73Å
380	F	91.5	Very high	84.6	Confident	131 Å²	131	46.9 Å²	46.9	58%	0.575	23%	0.232	S	C	*	.	H	α-helix	trans	-62.7	-46.6	175.4	179.5	-97.6	0	0	0	111.9	I376 P377 L378 C382 F383 T384	I376-F380 WeakPolarHBondContact O-CB 3.36Å; I376-F380 PolarHBondContact O-N 2.96Å; P377-F380 PolarHBondContact O-N 3.23Å; L378-F380 VanDerWaalsContact C-N 3.32Å; L378-F380 PolarHBondContact O-N 3.43Å; F380-C382 VanDerWaalsContact C-N 3.32Å; F380-C382 PolarHBondContact O-N 2.73Å; F380-F383 PolarHBondContact O-N 2.93Å; F380-T384 HydrophobicContact CD1-CG2 4.28Å; F380-T384 HydrophobicContact CD2-CG2 4.36Å; F380-T384 HydrophobicContact CE1-CG2 3.88Å; F380-T384 HydrophobicContact CE2-CG2 3.96Å; F380-T384 HydrophobicContact CZ-CG2 3.71Å; F380-T384 WeakPolarHBondContact O-CB 3.5Å; F380-T384 VanDerWaalsContact O-CG2 3.3Å; F380-T384 WeakPolarHBondContact O-CG2 3.36Å; F380-T384 PolarHBondContact O-N 2.96Å; F380-T384 PolarHBondContact O-OG1 3.49Å
381	L	92.5	Very high	86	Confident	18 Å²	18	50.3 Å²	50.3	9%	0.094	25%	0.251	C	S	.	.	H	α-helix	trans	-63.9	-38	176	-71.4	173.6	0	0	0	112.3	L181 Y184 L185 F188 P377 L378 T384 S385	L181-L381 HydrophobicContact CD2-CD1 4.36Å; Y184-L381 HydrophobicContact CD1-CB 4.38Å; L185-L381 HydrophobicContact CD2-CD1 3.81Å; L185-L381 HydrophobicContact CD2-CD2 3.66Å; L185-L381 HydrophobicContact CD2-CG 4.41Å; L185-L381 HydrophobicContact CG-CD1 3.88Å; F188-L381 HydrophobicContact CB-CD2 4.36Å; F188-L381 HydrophobicContact CG-CD2 4.38Å; P377-L381 VanDerWaalsContact O-CG 3.31Å; P377-L381 WeakPolarHBondContact O-CG 3.49Å; P377-L381 PolarHBondContact O-N 3.12Å; L378-L381 PolarHBondContact O-N 3.49Å; L381-T384 WeakPolarHBondContact CA-OG1 3.27Å; L381-T384 PolarHBondContact O-OG1 3.01Å; L381-T384 VanDerWaalsContact O-OG1 3.08Å; L381-S385 VanDerWaalsContact O-CB 3.25Å; L381-S385 WeakPolarHBondContact O-CB 3.43Å; L381-S385 PolarHBondContact O-N 3.31Å; L381-S385 PolarHBondContact O-OG 3.45Å
382	C	91.2	Very high	87	Confident	6 Å²	6	50 Å²	50	4%	0.041	25%	0.249	C	C	.	.	H	α-helix	trans	-63.2	-51.5	174.9	-176.6	0	0	0	0	111.4	Y184 L378 A379 F380 S385 I386 T428	Y184-C382 HydrophobicContact CD1-CB 4.36Å; Y184-C382 HydrophobicContact CE1-CB 3.82Å; L378-C382 VanDerWaalsContact O-CB 3.3Å; L378-C382 WeakPolarHBondContact O-CB 3.32Å; L378-C382 PolarHBondContact O-N 2.91Å; A379-C382 WeakPolarHBondContact O-CB 3.18Å; A379-C382 PolarHBondContact O-N 3.45Å; F380-C382 VanDerWaalsContact C-N 3.32Å; F380-C382 PolarHBondContact O-N 2.73Å; C382-S385 PolarHBondContact O-N 3.19Å; C382-I386 WeakPolarHBondContact O-CG1 3.27Å; C382-I386 PolarHBondContact O-N 3.08Å; C382-T428 WeakPolarHBondContact SG-CG2 3.46Å; C382-T428 PolarHBondContact SG-OG1 3.06Å
383	F	92.7	Very high	87.8	Confident	137 Å²	137	44.5 Å²	44.5	60%	0.601	24%	0.235	S	C	*	.	H	α-helix	trans	-59.8	-49	179.2	178.8	-100.1	0	0	0	111.7	A379 F380 S385 I386 V387	A379-F383 WeakPolarHBondContact O-CB 3.37Å; A379-F383 PolarHBondContact O-N 3.32Å; F380-F383 PolarHBondContact O-N 2.93Å; F383-S385 VanDerWaalsContact C-N 3.31Å; F383-S385 PolarHBondContact O-N 3.46Å; F383-I386 PolarHBondContact O-N 3.38Å; F383-V387 HydrophobicContact CD1-CG2 4.18Å; F383-V387 HydrophobicContact CE1-CG2 3.79Å; F383-V387 HydrophobicContact CE2-CG2 4.28Å; F383-V387 HydrophobicContact CZ-CG2 3.84Å; F383-V387 WeakPolarHBondContact O-CG2 3.46Å; F383-V387 PolarHBondContact O-N 2.68Å
384	T	93.1	Very high	88.5	Confident	25 Å²	25	46.6 Å²	46.6	15%	0.153	25%	0.245	C	C	.	.	H	α-helix	trans	-63.3	-35.9	178.5	52.3	0	0	0	0	112.5	F380 L381 V387 L388	F380-T384 HydrophobicContact CD1-CG2 4.28Å; F380-T384 HydrophobicContact CD2-CG2 4.36Å; F380-T384 HydrophobicContact CE1-CG2 3.88Å; F380-T384 HydrophobicContact CE2-CG2 3.96Å; F380-T384 HydrophobicContact CZ-CG2 3.71Å; F380-T384 WeakPolarHBondContact O-CB 3.5Å; F380-T384 VanDerWaalsContact O-CG2 3.3Å; F380-T384 WeakPolarHBondContact O-CG2 3.36Å; F380-T384 PolarHBondContact O-N 2.96Å; F380-T384 PolarHBondContact O-OG1 3.49Å; L381-T384 WeakPolarHBondContact CA-OG1 3.27Å; L381-T384 PolarHBondContact O-OG1 3.01Å; L381-T384 VanDerWaalsContact O-OG1 3.08Å; T384-V387 PolarHBondContact O-N 3.46Å; T384-L388 WeakPolarHBondContact O-CB 3.38Å; T384-L388 VanDerWaalsContact O-CG 3.32Å; T384-L388 WeakPolarHBondContact O-CG 3.2Å; T384-L388 PolarHBondContact O-N 2.89Å
385	S	93.2	Very high	88.9	Confident	2 Å²	2	48.3 Å²	48.3	1%	0.014	25%	0.252	C	S	.	.	H	α-helix	trans	-64.6	-42.7	174	-62.7	0	0	0	0	112.1	L381 C382 F383 L388 I389	L381-S385 VanDerWaalsContact O-CB 3.25Å; L381-S385 WeakPolarHBondContact O-CB 3.43Å; L381-S385 PolarHBondContact O-N 3.31Å; L381-S385 PolarHBondContact O-OG 3.45Å; C382-S385 PolarHBondContact O-N 3.19Å; F383-S385 VanDerWaalsContact C-N 3.31Å; F383-S385 PolarHBondContact O-N 3.46Å; S385-L388 PolarHBondContact O-N 2.73Å; S385-I389 VanDerWaalsContact O-CG1 3.29Å; S385-I389 WeakPolarHBondContact O-CG1 3.4Å; S385-I389 PolarHBondContact O-N 2.77Å
386	I	92.8	Very high	88.8	Confident	65 Å²	65	49.5 Å²	49.5	33%	0.333	26%	0.261	S	S	.	.	H	α-helix	trans	-63.4	-45.9	175.7	-66.5	166.8	0	0	0	110.6	C382 F383 L388 I389 I390 T428	C382-I386 WeakPolarHBondContact O-CG1 3.27Å; C382-I386 PolarHBondContact O-N 3.08Å; F383-I386 PolarHBondContact O-N 3.38Å; I386-L388 VanDerWaalsContact C-N 3.32Å; I386-L388 PolarHBondContact O-N 3.05Å; I386-I389 PolarHBondContact O-N 2.8Å; I386-I389 VanDerWaalsContact O-N 3.17Å; I386-I390 HydrophobicContact CG2-CD1 3.97Å; I386-I390 WeakPolarHBondContact O-CG1 3.33Å; I386-I390 PolarHBondContact O-N 3.28Å; I386-T428 HydrophobicContact CD1-CG2 4.26Å
387	V	93.7	Very high	88.2	Confident	55 Å²	55	50.4 Å²	50.4	33%	0.333	27%	0.266	S	S	.	.	H	α-helix	trans	-58.6	-44.3	176.1	171.6	0	0	0	0	110.8	F383 T384 I389 I390 L391	F383-V387 HydrophobicContact CD1-CG2 4.18Å; F383-V387 HydrophobicContact CE1-CG2 3.79Å; F383-V387 HydrophobicContact CE2-CG2 4.28Å; F383-V387 HydrophobicContact CZ-CG2 3.84Å; F383-V387 WeakPolarHBondContact O-CG2 3.46Å; F383-V387 PolarHBondContact O-N 2.68Å; T384-V387 PolarHBondContact O-N 3.46Å; V387-I389 PolarHBondContact O-N 3.25Å; V387-I390 PolarHBondContact O-N 3.24Å; V387-L391 HydrophobicContact CG1-CD1 3.84Å; V387-L391 HydrophobicContact CG1-CG 4.26Å; V387-L391 WeakPolarHBondContact O-CB 3.15Å; V387-L391 VanDerWaalsContact O-CG 3.29Å; V387-L391 WeakPolarHBondContact O-CG 3.48Å; V387-L391 PolarHBondContact O-N 3.31Å
388	L	92.4	Very high	87.3	Confident	16 Å²	16	53 Å²	53	8%	0.084	28%	0.282	C	S	.	.	H	α-helix	trans	-61.1	-42.4	175.7	-77.9	172.4	0	0	0	112.3	F188 L191 F192 Y195 T384 S385 I386 I390 L391 I392	F188-L388 HydrophobicContact CD2-CD1 3.67Å; F188-L388 HydrophobicContact CE2-CD1 3.53Å; F188-L388 HydrophobicContact CZ-CD1 4.36Å; L191-L388 HydrophobicContact CB-CB 4.28Å; L191-L388 HydrophobicContact CB-CD1 4.17Å; F192-L388 HydrophobicContact CB-CD1 4.36Å; Y195-L388 HydrophobicContact CG-CD2 4.48Å; T384-L388 WeakPolarHBondContact O-CB 3.38Å; T384-L388 VanDerWaalsContact O-CG 3.32Å; T384-L388 WeakPolarHBondContact O-CG 3.2Å; T384-L388 PolarHBondContact O-N 2.89Å; S385-L388 PolarHBondContact O-N 2.73Å; I386-L388 VanDerWaalsContact C-N 3.32Å; I386-L388 PolarHBondContact O-N 3.05Å; L388-I390 VanDerWaalsContact C-N 3.34Å; L388-I390 PolarHBondContact O-N 3.18Å; L388-L391 PolarHBondContact O-N 2.87Å; L388-I392 WeakPolarHBondContact O-CB 3.33Å; L388-I392 WeakPolarHBondContact O-CD1 3.44Å; L388-I392 WeakPolarHBondContact O-CG1 3.17Å; L388-I392 PolarHBondContact O-N 3.37Å
389	I	92	Very high	86	Confident	23 Å²	23	54.8 Å²	54.8	12%	0.118	29%	0.291	C	S	.	.	H	α-helix	trans	-60	-45.7	176.3	-70.2	162.9	0	0	0	110.7	L191 S385 I386 V387 I392 S393 F417 A424	L191-I389 HydrophobicContact CD1-CD1 4.04Å; L191-I389 HydrophobicContact CD1-CG1 3.78Å; L191-I389 HydrophobicContact CD2-CG1 3.79Å; L191-I389 HydrophobicContact CG-CG1 4.46Å; S385-I389 VanDerWaalsContact O-CG1 3.29Å; S385-I389 WeakPolarHBondContact O-CG1 3.4Å; S385-I389 PolarHBondContact O-N 2.77Å; I386-I389 PolarHBondContact O-N 2.8Å; I386-I389 VanDerWaalsContact O-N 3.17Å; V387-I389 PolarHBondContact O-N 3.25Å; I389-I392 PolarHBondContact O-N 3.41Å; I389-S393 WeakPolarHBondContact O-CB 3.42Å; I389-S393 PolarHBondContact O-N 3.48Å; I389-S393 PolarHBondContact O-OG 3.22Å; I389-F417 HydrophobicContact CG2-CZ 4.22Å; I389-A424 HydrophobicContact CD1-CB 3.64Å
390	I	92.1	Very high	84.2	Confident	90 Å²	90	56.4 Å²	56.4	46%	0.462	30%	0.3	S	S	.	.	H	α-helix	trans	-63.1	-48.5	178.2	-66.3	167.9	0	0	0	110.4	I386 V387 L388 I392 S393 I394	I386-I390 HydrophobicContact CG2-CD1 3.97Å; I386-I390 WeakPolarHBondContact O-CG1 3.33Å; I386-I390 PolarHBondContact O-N 3.28Å; V387-I390 PolarHBondContact O-N 3.24Å; L388-I390 VanDerWaalsContact C-N 3.34Å; L388-I390 PolarHBondContact O-N 3.18Å; I390-I392 PolarHBondContact O-N 2.79Å; I390-S393 PolarHBondContact O-N 3.24Å; I390-S393 VanDerWaalsContact O-N 3.16Å; I390-I394 HydrophobicContact CG2-CD1 3.71Å; I390-I394 HydrophobicContact CG2-CG1 4.33Å; I390-I394 WeakPolarHBondContact O-CG1 3.42Å; I390-I394 PolarHBondContact O-N 3.3Å
391	L	89.9	Confident	81.7	Confident	78 Å²	78	58.2 Å²	58.2	41%	0.408	32%	0.315	S	S	.	.	H	α-helix	trans	-59.8	-43.9	179	-73.9	172.9	0	0	0	112.4	V387 L388 K395	V387-L391 HydrophobicContact CG1-CD1 3.84Å; V387-L391 HydrophobicContact CG1-CG 4.26Å; V387-L391 WeakPolarHBondContact O-CB 3.15Å; V387-L391 VanDerWaalsContact O-CG 3.29Å; V387-L391 WeakPolarHBondContact O-CG 3.48Å; V387-L391 PolarHBondContact O-N 3.31Å; L388-L391 PolarHBondContact O-N 2.87Å; L391-K395 VanDerWaalsContact O-CB 3.26Å; L391-K395 WeakPolarHBondContact O-CB 3.37Å; L391-K395 PolarHBondContact O-N 3.12Å
392	I	86.5	Confident	79.5	Confident	0 Å²	0	62.1 Å²	62.1	0%	0	34%	0.335	C	S	.	.	H	α-helix	trans	-62.3	-45.6	175.5	-70.1	162.6	0	0	0	110	L191 H194 Y195 L198 L388 I389 I390 K395 T396 F417	L191-I392 HydrophobicContact CD2-CD1 4.37Å; L191-I392 WeakPolarHBondContact O-CD1 3.22Å; H194-I392 HydrophobicContact CB-CD1 4.46Å; Y195-I392 HydrophobicContact CD2-CG1 4.07Å; L198-I392 HydrophobicContact CD1-CB 4.48Å; L198-I392 HydrophobicContact CD1-CG1 4.4Å; L198-I392 HydrophobicContact CD1-CG2 3.74Å; L388-I392 WeakPolarHBondContact O-CB 3.33Å; L388-I392 WeakPolarHBondContact O-CD1 3.44Å; L388-I392 WeakPolarHBondContact O-CG1 3.17Å; L388-I392 PolarHBondContact O-N 3.37Å; I389-I392 PolarHBondContact O-N 3.41Å; I390-I392 PolarHBondContact O-N 2.79Å; I392-K395 PolarHBondContact O-N 3.13Å; I392-T396 HydrophobicContact CG2-CG2 4.36Å; I392-T396 WeakPolarHBondContact O-CG2 3.29Å; I392-T396 PolarHBondContact O-N 2.74Å; I392-T396 PolarHBondContact O-OG1 2.87Å; I392-T396 VanDerWaalsContact O-OG1 3.14Å; I392-F417 HydrophobicContact CB-CD2 4.41Å; I392-F417 HydrophobicContact CB-CE2 3.68Å; I392-F417 HydrophobicContact CB-CZ 3.95Å; I392-F417 HydrophobicContact CD1-CD2 4.04Å; I392-F417 HydrophobicContact CD1-CE2 3.73Å; I392-F417 HydrophobicContact CG1-CE2 4.31Å; I392-F417 HydrophobicContact CG2-CD1 4.35Å; I392-F417 HydrophobicContact CG2-CD2 3.69Å; I392-F417 HydrophobicContact CG2-CE1 4.02Å; I392-F417 HydrophobicContact CG2-CE2 3.31Å; I392-F417 HydrophobicContact CG2-CG 4.2Å; I392-F417 HydrophobicContact CG2-CZ 3.49Å; I392-F417 VanDerWaalsContact CG2-CZ 3.49Å
393	S	86.3	Confident	77.5	Confident	38 Å²	38	65.9 Å²	65.9	27%	0.266	35%	0.352	S	S	.	.	H	α-helix	trans	-62.3	-48.9	-178.1	-57.4	0	0	0	0	111.9	I389 I390 K395 T396 D397	I389-S393 WeakPolarHBondContact O-CB 3.42Å; I389-S393 PolarHBondContact O-N 3.48Å; I389-S393 PolarHBondContact O-OG 3.22Å; I390-S393 PolarHBondContact O-N 3.24Å; I390-S393 VanDerWaalsContact O-N 3.16Å; S393-K395 VanDerWaalsContact C-N 3.28Å; S393-K395 PolarHBondContact O-N 3.08Å; S393-T396 WeakPolarHBondContact CA-OG1 3.46Å; S393-T396 PolarHBondContact O-N 2.92Å; S393-T396 VanDerWaalsContact O-N 3.17Å; S393-T396 PolarHBondContact O-OG1 3.23Å; S393-D397 PolarHBondContact O-N 3.16Å
394	I	84.1	Confident	75.1	Confident	94 Å²	94	67.1 Å²	67.1	48%	0.482	37%	0.365	S	S	.	.	H	α-helix	trans	-55.7	-47.9	174.7	-67.6	168.3	0	0	0	109.7	I390 T396 D397 T398	I390-I394 HydrophobicContact CG2-CD1 3.71Å; I390-I394 HydrophobicContact CG2-CG1 4.33Å; I390-I394 WeakPolarHBondContact O-CG1 3.42Å; I390-I394 PolarHBondContact O-N 3.3Å; I394-T396 VanDerWaalsContact C-N 3.31Å; I394-T396 PolarHBondContact O-N 2.98Å; I394-D397 PolarHBondContact O-N 3Å; I394-T398 HydrophobicContact CG2-CG2 4.25Å; I394-T398 WeakPolarHBondContact O-CG2 3.07Å; I394-T398 PolarHBondContact O-N 3.47Å; I394-T398 PolarHBondContact O-OG1 2.97Å
395	K	81.6	Confident	72.6	Confident	39 Å²	39	75.1 Å²	75.1	17%	0.17	40%	0.4	C	S	.	.	H	α-helix	trans	-65.6	-33.5	-178.1	-166.8	173.8	-168.5	-169.3	0	113	L198 N199 Y202 L391 I392 S393 T398 N399	L198-K395 HydrophobicContact CB-CD 4.5Å; N199-K395 PolarHBondContact OD1-NZ 2.77Å; Y202-K395 HydrophobicContact CD2-CD 4.44Å; Y202-K395 HydrophobicContact CE2-CD 4.18Å; Y202-K395 HydrophobicContact CE2-CG 4.18Å; L391-K395 VanDerWaalsContact O-CB 3.26Å; L391-K395 WeakPolarHBondContact O-CB 3.37Å; L391-K395 PolarHBondContact O-N 3.12Å; I392-K395 PolarHBondContact O-N 3.13Å; S393-K395 VanDerWaalsContact C-N 3.28Å; S393-K395 PolarHBondContact O-N 3.08Å; K395-T398 PolarHBondContact O-OG1 3.5Å; K395-N399 WeakPolarHBondContact O-CB 3.06Å; K395-N399 PolarHBondContact O-ND2 3.23Å
396	T	75.8	Confident	70.2	Confident	42 Å²	42	80.5 Å²	80.5	26%	0.258	42%	0.423	S	S	.	.	H	α-helix	trans	-71.5	-39	175.3	48.3	0	0	0	0	111.9	L198 I392 S393 I394 N399 C400	L198-T396 HydrophobicContact CD1-CG2 4.24Å; L198-T396 HydrophobicContact CD2-CG2 4.43Å; I392-T396 HydrophobicContact CG2-CG2 4.36Å; I392-T396 WeakPolarHBondContact O-CG2 3.29Å; I392-T396 PolarHBondContact O-N 2.74Å; I392-T396 PolarHBondContact O-OG1 2.87Å; I392-T396 VanDerWaalsContact O-OG1 3.14Å; S393-T396 WeakPolarHBondContact CA-OG1 3.46Å; S393-T396 PolarHBondContact O-N 2.92Å; S393-T396 VanDerWaalsContact O-N 3.17Å; S393-T396 PolarHBondContact O-OG1 3.23Å; I394-T396 VanDerWaalsContact C-N 3.31Å; I394-T396 PolarHBondContact O-N 2.98Å; T396-N399 PolarHBondContact O-N 3.01Å; T396-C400 PolarHBondContact O-N 3.25Å; T396-C400 PolarHBondContact O-SG 3.02Å
397	D	72	Confident	68.1	Low	114 Å²	114	80.6 Å²	80.6	61%	0.61	43%	0.429	S	S	*	.	H	α-helix	trans	-72.3	-42.3	-178.2	-71.2	-14.6	0	0	0	112	S393 I394 N399 C400	S393-D397 PolarHBondContact O-N 3.16Å; I394-D397 PolarHBondContact O-N 3Å; D397-N399 PolarHBondContact O-N 3.46Å; D397-N399 VanDerWaalsContact O-N 3.15Å; D397-C400 PolarHBondContact O-N 2.9Å
398	T	66.6	Low	66	Low	96 Å²	96	81.1 Å²	81.1	59%	0.589	44%	0.436	S	S	*	.	H	α-helix	trans	-63.4	-23.2	178.3	56.4	0	0	0	0	113	I394 K395	I394-T398 HydrophobicContact CG2-CG2 4.25Å; I394-T398 WeakPolarHBondContact O-CG2 3.07Å; I394-T398 PolarHBondContact O-N 3.47Å; I394-T398 PolarHBondContact O-OG1 2.97Å; K395-T398 PolarHBondContact O-OG1 3.5Å
399	N	58.5	Low	64.3	Low	48 Å²	48	85.9 Å²	85.9	26%	0.257	46%	0.458	S	S	.	.	T	Hydrogen-bonded Turn	trans	-108.8	13.3	-173.6	-66.4	-47.5	0	0	0	113.5	Y202 K395 T396 D397 L401 I402	Y202-N399 HydrophobicContact CE1-CB 3.68Å; Y202-N399 VanDerWaalsContact CZ-ND2 3.31Å; Y202-N399 VanDerWaalsContact OH-CB 3.25Å; Y202-N399 WeakPolarHBondContact OH-CB 3.42Å; Y202-N399 PolarHBondContact OH-ND2 2.8Å; K395-N399 WeakPolarHBondContact O-CB 3.06Å; K395-N399 PolarHBondContact O-ND2 3.23Å; T396-N399 PolarHBondContact O-N 3.01Å; D397-N399 PolarHBondContact O-N 3.46Å; D397-N399 VanDerWaalsContact O-N 3.15Å; N399-L401 PolarHBondContact O-N 3.22Å; N399-I402 PolarHBondContact O-N 3.45Å
400	C	49	Very low	62.9	Low	67 Å²	67	86 Å²	86	45%	0.453	46%	0.461	S	S	.	.	T	Hydrogen-bonded Turn	trans	-59.6	-0.4	178.9	-90.6	0	0	0	0	115.6	T396 D397	T396-C400 PolarHBondContact O-N 3.25Å; T396-C400 PolarHBondContact O-SG 3.02Å; D397-C400 PolarHBondContact O-N 2.9Å
401	L	39.5	Very low	61.6	Low	169 Å²	169	86.7 Å²	86.7	89%	0.885	46%	0.464	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.5	-8.3	175.1	-83.8	156.8	0	0	0	114.8	N399	N399-L401 PolarHBondContact O-N 3.22Å
402	I	46.3	Very low	60.5	Low	101 Å²	101	85.2 Å²	85.2	52%	0.518	46%	0.457	S	S	.	.	S	Bend	trans	-109.8	14.2	-175.7	-50.7	172.1	0	0	0	111.6	N399 D404	N399-I402 PolarHBondContact O-N 3.45Å; I402-D404 VanDerWaalsContact C-N 3.34Å; I402-D404 PolarHBondContact O-N 3.23Å
403	Q	49.9	Very low	59.8	Low	85 Å²	85	87.2 Å²	87.2	40%	0.397	47%	0.469	S	S	.	.	G	3₁₀ helix	trans	-82.2	-1.6	-164.7	-141.6	158.9	19.5	0	0	115.9	H405 F406	Q403-H405 PolarHBondContact O-N 3.17Å; Q403-F406 HydrophobicContact CB-CD2 4.32Å; Q403-F406 HydrophobicContact CB-CE2 4.5Å; Q403-F406 HydrophobicContact CG-CD2 3.79Å; Q403-F406 HydrophobicContact CG-CE2 4.08Å; Q403-F406 WeakPolarHBondContact O-CD2 3.09Å
404	D	41.6	Very low	59.3	Low	162 Å²	162	88.7 Å²	88.7	87%	0.866	47%	0.471	S	S	*	.	G	3₁₀ helix	trans	-86.2	-3.1	-169.9	-71.5	-19	0	0	0	115.7	I402	I402-D404 VanDerWaalsContact C-N 3.34Å; I402-D404 PolarHBondContact O-N 3.23Å
405	H	40.5	Very low	59	Low	193 Å²	193	84.9 Å²	84.9	89%	0.894	45%	0.453	S	S	*	.	G	3₁₀ helix	trans	-110.8	20.8	-179.7	-94.8	-31.5	0	0	0	115.9	Q403 S407	Q403-H405 PolarHBondContact O-N 3.17Å; H405-S407 PolarHBondContact O-N 3.5Å
406	F	43.5	Very low	59	Low	116 Å²	116	85.5 Å²	85.5	51%	0.509	46%	0.455	S	S	.	.			trans	-89.4	107.1	-165	-90.2	-56.8	0	0	0	113.8	Q403 S410	Q403-F406 HydrophobicContact CB-CD2 4.32Å; Q403-F406 HydrophobicContact CB-CE2 4.5Å; Q403-F406 HydrophobicContact CG-CD2 3.79Å; Q403-F406 HydrophobicContact CG-CE2 4.08Å; Q403-F406 WeakPolarHBondContact O-CD2 3.09Å; F406-S410 VanDerWaalsContact CB-CB 3.46Å; F406-S410 WeakPolarHBondContact CB-OG 3.23Å; F406-S410 VanDerWaalsContact CD1-CB 3.42Å
407	S	48.7	Very low	59.4	Low	66 Å²	66	84.5 Å²	84.5	46%	0.462	45%	0.447	S	S	.	.			trans	-54.1	166	169.8	68.5	0	0	0	0	112.5	H405 Q409 S410	H405-S407 PolarHBondContact O-N 3.5Å; S407-Q409 PolarHBondContact O-N 3.44Å; S407-S410 WeakPolarHBondContact O-CB 3.43Å; S407-S410 PolarHBondContact O-N 3.18Å; S407-S410 PolarHBondContact O-OG 3.45Å
408	S	49.6	Very low	60.1	Low	67 Å²	67	84.1 Å²	84.1	47%	0.469	44%	0.437	S	S	.	.	H	α-helix	trans	-48.2	-26.1	176.7	51.9	0	0	0	0	114.8	S410 L411	S408-S410 VanDerWaalsContact C-N 3.29Å; S408-S410 PolarHBondContact O-N 2.98Å; S408-L411 PolarHBondContact O-N 2.8Å
409	Q	55.4	Low	61.1	Low	116 Å²	116	79.8 Å²	79.8	54%	0.542	41%	0.41	S	S	.	.	H	α-helix	trans	-64.5	-30.2	176.9	-66.1	-178.3	-2.8	0	0	113.2	S407 V413	S407-Q409 PolarHBondContact O-N 3.44Å; Q409-V413 WeakPolarHBondContact O-CB 3.42Å; Q409-V413 WeakPolarHBondContact O-CG2 3.43Å; Q409-V413 PolarHBondContact O-N 3.15Å; Q409-V413 VanDerWaalsContact O-N 3.1Å
410	S	62.8	Low	62.6	Low	26 Å²	26	78 Å²	78	18%	0.182	40%	0.4	C	S	.	.	H	α-helix	trans	-65.9	-37.5	178.9	67	0	0	0	0	113.5	F406 S407 S408 V413 K414	F406-S410 VanDerWaalsContact CB-CB 3.46Å; F406-S410 WeakPolarHBondContact CB-OG 3.23Å; F406-S410 VanDerWaalsContact CD1-CB 3.42Å; S407-S410 WeakPolarHBondContact O-CB 3.43Å; S407-S410 PolarHBondContact O-N 3.18Å; S407-S410 PolarHBondContact O-OG 3.45Å; S408-S410 VanDerWaalsContact C-N 3.29Å; S408-S410 PolarHBondContact O-N 2.98Å; S410-V413 PolarHBondContact O-N 3.4Å; S410-K414 WeakPolarHBondContact O-CB 3.25Å; S410-K414 PolarHBondContact O-N 3.39Å
411	L	64.8	Low	64.6	Low	103 Å²	103	75.5 Å²	75.5	54%	0.539	38%	0.383	S	S	.	.	H	α-helix	trans	-69.2	-44	-178.8	-71.1	172	0	0	0	109.7	S408 V413 K414 A415	S408-L411 PolarHBondContact O-N 2.8Å; L411-V413 PolarHBondContact O-N 3.43Å; L411-K414 PolarHBondContact O-N 2.78Å; L411-A415 VanDerWaalsContact O-CB 3.26Å; L411-A415 WeakPolarHBondContact O-CB 3.4Å; L411-A415 PolarHBondContact O-N 3.32Å
412	D	68.2	Low	67.1	Low	47 Å²	47	71 Å²	71	25%	0.251	36%	0.356	S	S	.	.	H	α-helix	trans	-61.6	-44	175.8	-67.5	-10.6	0	0	0	111.3	L119 A415 R416	L119-D412 HydrophobicContact CD1-CB 3.93Å; D412-A415 PolarHBondContact O-N 3.27Å; D412-R416 WeakPolarHBondContact O-CG 3.37Å; D412-R416 PolarHBondContact O-N 2.03Å
413	V	71.3	Confident	69.3	Low	42 Å²	42	66.1 Å²	66.1	26%	0.255	33%	0.332	S	S	.	.	H	α-helix	trans	-65.5	-43.7	-179.7	168.1	0	0	0	0	111.3	H194 Q409 S410 L411 R416 F417	H194-V413 WeakPolarHBondContact CE1-CG1 3.26Å; H194-V413 PolarHBondContact CE1-O 2.94Å; Q409-V413 WeakPolarHBondContact O-CB 3.42Å; Q409-V413 WeakPolarHBondContact O-CG2 3.43Å; Q409-V413 PolarHBondContact O-N 3.15Å; Q409-V413 VanDerWaalsContact O-N 3.1Å; S410-V413 PolarHBondContact O-N 3.4Å; L411-V413 PolarHBondContact O-N 3.43Å; V413-R416 PolarHBondContact O-N 3.32Å; V413-F417 PolarHBondContact O-N 3.25Å; V413-F417 VanDerWaalsContact O-N 3.13Å
414	K	75.7	Confident	71.3	Confident	69 Å²	69	62.3 Å²	62.3	30%	0.3	31%	0.314	S	S	.	.	H	α-helix	trans	-66.1	-37.8	175.2	-172.6	170.1	-175.9	166.5	0	112.1	S410 L411 F417 R418 H499	S410-K414 WeakPolarHBondContact O-CB 3.25Å; S410-K414 PolarHBondContact O-N 3.39Å; L411-K414 PolarHBondContact O-N 2.78Å; K414-F417 PolarHBondContact O-N 2.76Å; K414-R418 WeakPolarHBondContact O-CG 3.16Å; K414-R418 PolarHBondContact O-N 3.31Å; K414-R418 VanDerWaalsContact O-N 3.16Å; K414-H499 PolarHBondContact NZ-NE2 2.85Å
415	A	76.8	Confident	73.7	Confident	14 Å²	14	59.8 Å²	59.8	12%	0.116	30%	0.3	C	S	.	.	H	α-helix	trans	-64.2	-44.8	175.6	0	0	0	0	0	112	L411 D412 F417 R418 M419 P469	L411-A415 VanDerWaalsContact O-CB 3.26Å; L411-A415 WeakPolarHBondContact O-CB 3.4Å; L411-A415 PolarHBondContact O-N 3.32Å; D412-A415 PolarHBondContact O-N 3.27Å; A415-F417 PolarHBondContact O-N 2.7Å; A415-R418 WeakPolarHBondContact O-CB 3.37Å; A415-R418 PolarHBondContact O-N 3.18Å; A415-M419 WeakPolarHBondContact O-CG 3.42Å; A415-M419 PolarHBondContact O-N 3.17Å; A415-P469 HydrophobicContact CB-CB 4.44Å; A415-P469 HydrophobicContact CB-CG 3.65Å
416	R	81.8	Confident	76.2	Confident	52 Å²	52	51.2 Å²	51.2	20%	0.196	26%	0.261	C	S	.	.	H	α-helix	trans	-59.2	-45.2	175.6	-74.7	-179.2	-148	-170.7	2	112.4	R118 L119 D412 V413 R418 M419 F420	R118-R416 PolarHBondContact O-NH2 3.25Å; L119-R416 VanDerWaalsContact O-CD 3.28Å; L119-R416 WeakPolarHBondContact O-CD 3.24Å; L119-R416 WeakPolarHBondContact O-CG 3.33Å; L119-R416 PolarHBondContact O-NE 3.38Å; D412-R416 WeakPolarHBondContact O-CG 3.37Å; D412-R416 PolarHBondContact O-N 2.03Å; V413-R416 PolarHBondContact O-N 3.32Å; R416-R418 VanDerWaalsContact C-N 3.29Å; R416-R418 PolarHBondContact O-N 3.15Å; R416-M419 WeakPolarHBondContact O-CB 3.34Å; R416-M419 PolarHBondContact O-N 3.33Å; R416-M419 VanDerWaalsContact O-N 3.1Å; R416-F420 HydrophobicContact CB-CD2 4.47Å; R416-F420 HydrophobicContact CB-CE2 4.42Å; R416-F420 WeakPolarHBondContact O-CD2 3.42Å; R416-F420 PolarHBondContact O-N 3.07Å
417	F	85.7	Confident	78.5	Confident	22 Å²	22	46 Å²	46	10%	0.096	24%	0.238	C	C	.	.	H	α-helix	trans	-57.7	-43.7	176.6	171.5	-109.8	0	0	0	112	L191 H194 I389 I392 V413 K414 A415 M419 F420 S421	L191-F417 HydrophobicContact CD2-CD2 4.06Å; L191-F417 HydrophobicContact CD2-CE2 4.05Å; H194-F417 AromaticContact CD2-CD2 3.87Å; H194-F417 AromaticContact NE2-CG 3.87Å; I389-F417 HydrophobicContact CG2-CZ 4.22Å; I392-F417 HydrophobicContact CB-CD2 4.41Å; I392-F417 HydrophobicContact CB-CE2 3.68Å; I392-F417 HydrophobicContact CB-CZ 3.95Å; I392-F417 HydrophobicContact CD1-CD2 4.04Å; I392-F417 HydrophobicContact CD1-CE2 3.73Å; I392-F417 HydrophobicContact CG1-CE2 4.31Å; I392-F417 HydrophobicContact CG2-CD1 4.35Å; I392-F417 HydrophobicContact CG2-CD2 3.69Å; I392-F417 HydrophobicContact CG2-CE1 4.02Å; I392-F417 HydrophobicContact CG2-CE2 3.31Å; I392-F417 HydrophobicContact CG2-CG 4.2Å; I392-F417 HydrophobicContact CG2-CZ 3.49Å; I392-F417 VanDerWaalsContact CG2-CZ 3.49Å; V413-F417 PolarHBondContact O-N 3.25Å; V413-F417 VanDerWaalsContact O-N 3.13Å; K414-F417 PolarHBondContact O-N 2.76Å; A415-F417 PolarHBondContact O-N 2.7Å; F417-M419 VanDerWaalsContact C-N 3.34Å; F417-M419 PolarHBondContact O-N 2.94Å; F417-F420 PolarHBondContact O-N 3.15Å; F417-S421 WeakPolarHBondContact O-CB 3.25Å; F417-S421 PolarHBondContact O-N 3.24Å; F417-S421 PolarHBondContact O-OG 2.79Å
418	R	85.7	Confident	80.5	Confident	105 Å²	105	44 Å²	44	40%	0.396	22%	0.223	S	C	.	.	H	α-helix	trans	-63	-40.5	174.9	-70.8	176.5	173.9	-169.8	-5.1	111.9	K414 A415 R416 S421 K422 H499	K414-R418 WeakPolarHBondContact O-CG 3.16Å; K414-R418 PolarHBondContact O-N 3.31Å; K414-R418 VanDerWaalsContact O-N 3.16Å; A415-R418 WeakPolarHBondContact O-CB 3.37Å; A415-R418 PolarHBondContact O-N 3.18Å; R416-R418 VanDerWaalsContact C-N 3.29Å; R416-R418 PolarHBondContact O-N 3.15Å; R418-S421 PolarHBondContact O-N 2.89Å; R418-K422 WeakPolarHBondContact O-CG 3.15Å; R418-K422 PolarHBondContact O-N 3.25Å; R418-H499 PolarHBondContact NH2-CE1 3.38Å
419	M	88.6	Confident	82.5	Confident	5 Å²	5	45.7 Å²	45.7	3%	0.025	22%	0.223	C	C	.	.	H	α-helix	trans	-61.6	-49.3	175.9	-72.9	176	-179.3	0	0	111.6	L119 L124 A415 R416 F417 S421 K422 I423 F464 S467	L119-M419 HydrophobicContact CD2-CE 4.44Å; L124-M419 HydrophobicContact CD2-CB 4.1Å; L124-M419 HydrophobicContact CD2-SD 3.73Å; A415-M419 WeakPolarHBondContact O-CG 3.42Å; A415-M419 PolarHBondContact O-N 3.17Å; R416-M419 WeakPolarHBondContact O-CB 3.34Å; R416-M419 PolarHBondContact O-N 3.33Å; R416-M419 VanDerWaalsContact O-N 3.1Å; F417-M419 VanDerWaalsContact C-N 3.34Å; F417-M419 PolarHBondContact O-N 2.94Å; M419-S421 VanDerWaalsContact C-N 3.35Å; M419-S421 PolarHBondContact O-N 3Å; M419-K422 PolarHBondContact O-N 3.34Å; M419-I423 PolarHBondContact O-N 3.49Å; M419-F464 HydrophobicContact CB-CD1 4.35Å; M419-F464 HydrophobicContact CB-CE1 3.6Å; M419-F464 HydrophobicContact CB-CE2 4.13Å; M419-F464 HydrophobicContact CB-CZ 3.43Å; M419-F464 VanDerWaalsContact CB-CZ 3.43Å; M419-F464 HydrophobicContact CG-CD1 3.84Å; M419-F464 HydrophobicContact CG-CE1 3.6Å; M419-F464 HydrophobicContact CG-CE2 4.28Å; M419-F464 HydrophobicContact CG-CG 4.31Å; M419-F464 HydrophobicContact CG-CZ 3.8Å; M419-F464 WeakPolarHBondContact O-CZ 3.28Å; M419-S467 WeakPolarHBondContact CE-OG 3.45Å
420	F	90.4	Very high	84.2	Confident	11 Å²	11	40.8 Å²	40.8	5%	0.048	20%	0.2	C	C	.	.	H	α-helix	trans	-60.5	-42.6	175.4	-77.3	-64.4	0	0	0	112.2	C123 L124 I127 L191 R416 F417 K422 I423 A424	C123-F420 HydrophobicContact CB-CZ 4.17Å; L124-F420 HydrophobicContact CB-CE1 4.39Å; L124-F420 HydrophobicContact CB-CZ 4.13Å; L124-F420 HydrophobicContact CD1-CD1 4.17Å; L124-F420 HydrophobicContact CD1-CE1 3.95Å; L124-F420 HydrophobicContact CD1-CZ 4.33Å; I127-F420 HydrophobicContact CD1-CD1 4.2Å; I127-F420 HydrophobicContact CD1-CE1 3.65Å; L191-F420 HydrophobicContact CD2-CB 3.73Å; L191-F420 HydrophobicContact CG-CB 4.13Å; R416-F420 HydrophobicContact CB-CD2 4.47Å; R416-F420 HydrophobicContact CB-CE2 4.42Å; R416-F420 WeakPolarHBondContact O-CD2 3.42Å; R416-F420 PolarHBondContact O-N 3.07Å; F417-F420 PolarHBondContact O-N 3.15Å; F420-K422 PolarHBondContact O-N 2.97Å; F420-I423 PolarHBondContact O-N 3.15Å; F420-A424 VanDerWaalsContact O-CB 3.31Å; F420-A424 WeakPolarHBondContact O-CB 3.45Å; F420-A424 PolarHBondContact O-N 3.31Å
421	S	90.7	Very high	85.5	Confident	14 Å²	14	41.9 Å²	41.9	10%	0.098	20%	0.2	C	C	.	.	H	α-helix	trans	-62.4	-44.3	178.7	-58.1	0	0	0	0	111.8	F417 R418 M419 A424 I425	F417-S421 WeakPolarHBondContact O-CB 3.25Å; F417-S421 PolarHBondContact O-N 3.24Å; F417-S421 PolarHBondContact O-OG 2.79Å; R418-S421 PolarHBondContact O-N 2.89Å; M419-S421 VanDerWaalsContact C-N 3.35Å; M419-S421 PolarHBondContact O-N 3Å; S421-A424 PolarHBondContact O-N 3.41Å; S421-I425 WeakPolarHBondContact O-CD1 3.28Å; S421-I425 VanDerWaalsContact O-CG1 3.27Å; S421-I425 WeakPolarHBondContact O-CG1 2.93Å; S421-I425 PolarHBondContact O-N 2.74Å
422	K	91.7	Very high	86.6	Confident	74 Å²	74	40.7 Å²	40.7	32%	0.322	19%	0.193	S	C	.	.	H	α-helix	trans	-62.3	-43.9	176.7	-75	-175.7	173.9	-167	0	112.2	R418 M419 F420 S426 Y459 S463	R418-K422 WeakPolarHBondContact O-CG 3.15Å; R418-K422 PolarHBondContact O-N 3.25Å; M419-K422 PolarHBondContact O-N 3.34Å; F420-K422 PolarHBondContact O-N 2.97Å; K422-S426 WeakPolarHBondContact O-CB 3.16Å; K422-S426 PolarHBondContact O-N 2.88Å; K422-S426 PolarHBondContact O-OG 3.49Å; K422-Y459 HydrophobicContact CB-CE1 4.26Å; K422-Y459 WeakPolarHBondContact CG-OH 2.98Å; K422-S463 PolarHBondContact NZ-OG 2.87Å
423	I	91.9	Very high	87.5	Confident	0 Å²	0	39.9 Å²	39.9	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-64.6	-45.3	176.2	-76.6	179.7	0	0	0	110.7	L124 I127 I187 M419 F420 I425 S426 H427 I460 F464	L124-I423 HydrophobicContact CD1-CD1 3.62Å; I127-I423 HydrophobicContact CG2-CD1 4.22Å; I127-I423 HydrophobicContact CG2-CG2 4.19Å; I187-I423 HydrophobicContact CD1-CG2 3.55Å; I187-I423 HydrophobicContact CG1-CG2 3.73Å; M419-I423 PolarHBondContact O-N 3.49Å; F420-I423 PolarHBondContact O-N 3.15Å; I423-I425 PolarHBondContact O-N 3.19Å; I423-S426 PolarHBondContact O-N 3.41Å; I423-S426 PolarHBondContact O-OG 3.2Å; I423-H427 WeakPolarHBondContact CG2-ND1 2.9Å; I423-H427 WeakPolarHBondContact O-CB 3.12Å; I423-H427 PolarHBondContact O-N 3.38Å; I423-H427 PolarHBondContact O-ND1 2.87Å; I423-I460 HydrophobicContact CD1-CG2 4.4Å; I423-I460 HydrophobicContact CG1-CD1 4.23Å; I423-I460 HydrophobicContact CG1-CG1 4.17Å; I423-I460 HydrophobicContact CG1-CG2 4.36Å; I423-F464 HydrophobicContact CD1-CE1 4.49Å; I423-F464 HydrophobicContact CD1-CE2 3.56Å; I423-F464 HydrophobicContact CD1-CZ 3.33Å; I423-F464 HydrophobicContact CG1-CE1 4.31Å; I423-F464 HydrophobicContact CG1-CE2 4.22Å; I423-F464 HydrophobicContact CG1-CZ 3.54Å
424	A	92.5	Very high	88	Confident	4 Å²	4	38.5 Å²	38.5	3%	0.033	18%	0.182	C	C	.	.	H	α-helix	trans	-57.9	-52.7	-179.7	0	0	0	0	0	110.8	I187 I389 F420 S421 S426 H427 T428	I187-A424 HydrophobicContact CG2-CB 3.75Å; I389-A424 HydrophobicContact CD1-CB 3.64Å; F420-A424 VanDerWaalsContact O-CB 3.31Å; F420-A424 WeakPolarHBondContact O-CB 3.45Å; F420-A424 PolarHBondContact O-N 3.31Å; S421-A424 PolarHBondContact O-N 3.41Å; A424-S426 VanDerWaalsContact C-N 3.33Å; A424-S426 PolarHBondContact O-N 3.41Å; A424-H427 PolarHBondContact O-N 3.12Å; A424-T428 PolarHBondContact O-N 3.31Å; A424-T428 PolarHBondContact O-OG1 3.24Å
425	I	91.4	Very high	88.3	Confident	110 Å²	110	38.3 Å²	38.3	56%	0.564	18%	0.182	S	C	*	.	H	α-helix	trans	-59.5	-44.7	179.1	-65.1	165	0	0	0	110.9	S421 I423 H427 T428 F429	S421-I425 WeakPolarHBondContact O-CD1 3.28Å; S421-I425 VanDerWaalsContact O-CG1 3.27Å; S421-I425 WeakPolarHBondContact O-CG1 2.93Å; S421-I425 PolarHBondContact O-N 2.74Å; I423-I425 PolarHBondContact O-N 3.19Å; I425-H427 VanDerWaalsContact C-N 3.32Å; I425-H427 PolarHBondContact O-N 3.27Å; I425-T428 PolarHBondContact O-N 3.33Å; I425-F429 PolarHBondContact O-N 2.71Å; I425-F429 VanDerWaalsContact O-N 3.1Å
426	S	93.1	Very high	88.6	Confident	12 Å²	12	41 Å²	41	8%	0.084	19%	0.193	C	C	.	.	H	α-helix	trans	-66.4	-34.4	-179.6	77.7	0	0	0	0	112.3	K422 I423 A424 L430 Q456	K422-S426 WeakPolarHBondContact O-CB 3.16Å; K422-S426 PolarHBondContact O-N 2.88Å; K422-S426 PolarHBondContact O-OG 3.49Å; I423-S426 PolarHBondContact O-N 3.41Å; I423-S426 PolarHBondContact O-OG 3.2Å; A424-S426 VanDerWaalsContact C-N 3.33Å; A424-S426 PolarHBondContact O-N 3.41Å; S426-L430 PolarHBondContact O-N 3.43Å; S426-Q456 PolarHBondContact O-NE2 2.91Å; S426-Q456 PolarHBondContact OG-NE2 3.36Å; S426-Q456 VanDerWaalsContact OG-NE2 3.15Å
427	H	91.9	Very high	88.6	Confident	6 Å²	6	38.5 Å²	38.5	3%	0.028	18%	0.184	C	C	.	.	H	α-helix	trans	-74.2	-40.1	177.1	-77.5	71.1	0	0	0	111.3	N131 Y184 I187 I423 A424 I425 F429 L430 W431 Q456	N131-H427 PolarHBondContact ND2-CE1 3.39Å; N131-H427 VanDerWaalsContact ND2-CE1 3.28Å; N131-H427 PolarHBondContact ND2-NE2 2.88Å; N131-H427 PolarHBondContact OD1-NE2 3.19Å; N131-H427 VanDerWaalsContact OD1-NE2 3.09Å; Y184-H427 HydrophobicContact CE1-CB 4.38Å; Y184-H427 HydrophobicContact CE2-CB 4.18Å; Y184-H427 PolarHBondContact OH-O 3.27Å; I187-H427 HydrophobicContact CD1-CB 4.33Å; I423-H427 WeakPolarHBondContact CG2-ND1 2.9Å; I423-H427 WeakPolarHBondContact O-CB 3.12Å; I423-H427 PolarHBondContact O-N 3.38Å; I423-H427 PolarHBondContact O-ND1 2.87Å; A424-H427 PolarHBondContact O-N 3.12Å; I425-H427 VanDerWaalsContact C-N 3.32Å; I425-H427 PolarHBondContact O-N 3.27Å; H427-F429 VanDerWaalsContact C-N 3.29Å; H427-F429 PolarHBondContact O-N 3.41Å; H427-L430 PolarHBondContact O-N 3.21Å; H427-W431 WeakPolarHBondContact O-CB 3.25Å; H427-W431 PolarHBondContact O-N 3.27Å; H427-Q456 PolarHBondContact CE1-NE2 3.1Å; H427-Q456 VanDerWaalsContact CE1-NE2 3.28Å; H427-Q456 PolarHBondContact ND1-NE2 3.08Å; H427-Q456 VanDerWaalsContact ND1-NE2 3.13Å
428	T	91.6	Very high	88.1	Confident	24 Å²	24	38.3 Å²	38.3	15%	0.147	18%	0.184	C	C	.	.	H	α-helix	trans	-54.9	-47	173.4	-58.8	0	0	0	0	111.1	Y184 C382 I386 A424 I425 L430 W431 I432	Y184-T428 PolarHBondContact OH-N 3.31Å; C382-T428 WeakPolarHBondContact SG-CG2 3.46Å; C382-T428 PolarHBondContact SG-OG1 3.06Å; I386-T428 HydrophobicContact CD1-CG2 4.26Å; A424-T428 PolarHBondContact O-N 3.31Å; A424-T428 PolarHBondContact O-OG1 3.24Å; I425-T428 PolarHBondContact O-N 3.33Å; T428-L430 PolarHBondContact O-N 2Å; T428-W431 PolarHBondContact O-N 3.38Å; T428-I432 HydrophobicContact CG2-CD1 4.15Å; T428-I432 WeakPolarHBondContact O-CG1 3.32Å; T428-I432 PolarHBondContact O-N 2.91Å
429	F	91.9	Very high	87.7	Confident	103 Å²	103	40.3 Å²	40.3	45%	0.452	19%	0.193	S	C	.	.	H	α-helix	trans	-60	-46.7	178.1	177.3	-101.5	0	0	0	112.4	I425 H427 W431 I432 L433 F452	I425-F429 PolarHBondContact O-N 2.71Å; I425-F429 VanDerWaalsContact O-N 3.1Å; H427-F429 VanDerWaalsContact C-N 3.29Å; H427-F429 PolarHBondContact O-N 3.41Å; F429-W431 VanDerWaalsContact C-N 3.34Å; F429-W431 PolarHBondContact O-N 2.99Å; F429-I432 PolarHBondContact O-N 3.24Å; F429-L433 HydrophobicContact CD1-CD1 3.92Å; F429-L433 HydrophobicContact CE1-CD1 3.32Å; F429-L433 HydrophobicContact CE1-CG 4.4Å; F429-L433 HydrophobicContact CE2-CD1 4.43Å; F429-L433 HydrophobicContact CZ-CD1 3.62Å; F429-L433 HydrophobicContact CZ-CG 4.36Å; F429-L433 PolarHBondContact O-N 3.31Å; F429-F452 AromaticContact CE1-CD1 3.72Å; F429-F452 HydrophobicContact CE1-CD1 3.72Å; F429-F452 AromaticContact CE1-CE1 3.95Å; F429-F452 HydrophobicContact CE1-CE1 3.95Å; F429-F452 HydrophobicContact CE1-CG 4.16Å; F429-F452 HydrophobicContact CZ-CD1 4.33Å; F429-F452 HydrophobicContact CZ-CE1 4.12Å; F429-F452 HydrophobicContact CZ-CZ 4.44Å
430	L	90.9	Very high	87.1	Confident	13 Å²	13	44.8 Å²	44.8	7%	0.068	22%	0.216	C	C	.	.	H	α-helix	trans	-64.8	-37.3	176.7	-74.6	-165.1	0	0	0	113.1	S426 H427 T428 I432 L433 A434 Y449 F452 I453 Q456	S426-L430 PolarHBondContact O-N 3.43Å; H427-L430 PolarHBondContact O-N 3.21Å; T428-L430 PolarHBondContact O-N 2Å; L430-I432 VanDerWaalsContact C-N 3.34Å; L430-L433 HydrophobicContact CD2-CD1 4.34Å; L430-L433 PolarHBondContact O-N 2.8Å; L430-A434 WeakPolarHBondContact O-CB 3.44Å; L430-A434 PolarHBondContact O-N 2.74Å; L430-Y449 HydrophobicContact CB-CE2 4.32Å; L430-F452 HydrophobicContact CD2-CB 3.56Å; L430-I453 HydrophobicContact CD1-CG1 3.9Å; L430-Q456 HydrophobicContact CD1-CB 3.76Å; L430-Q456 HydrophobicContact CD1-CG 3.8Å; L430-Q456 HydrophobicContact CD2-CB 4.44Å; L430-Q456 HydrophobicContact CG-CB 4.2Å; L430-Q456 HydrophobicContact CG-CG 4.11Å
431	W	88.9	Confident	86.3	Confident	50 Å²	50	44.9 Å²	44.9	19%	0.189	22%	0.217	C	C	.	.	H	α-helix	trans	-64.4	-40.4	177.7	173	76.1	0	0	0	111.8	Y184 H375 L378 A379 H427 T428 F429 L433 A434 F435	Y184-W431 WeakPolarHBondContact OH-CB 3.4Å; H375-W431 HydrophobicContact CB-CZ2 4.31Å; H375-W431 AromaticContact CD2-NE1 3.57Å; L378-W431 HydrophobicContact CD2-CG 4.29Å; L378-W431 HydrophobicContact CG-CG 4.44Å; A379-W431 HydrophobicContact CB-CH2 3.77Å; A379-W431 HydrophobicContact CB-CZ2 3.73Å; H427-W431 WeakPolarHBondContact O-CB 3.25Å; H427-W431 PolarHBondContact O-N 3.27Å; T428-W431 PolarHBondContact O-N 3.38Å; F429-W431 VanDerWaalsContact C-N 3.34Å; F429-W431 PolarHBondContact O-N 2.99Å; W431-L433 VanDerWaalsContact C-N 3.33Å; W431-L433 PolarHBondContact O-N 3.45Å; W431-A434 PolarHBondContact O-N 3.38Å; W431-F435 VanDerWaalsContact O-CB 3.3Å; W431-F435 WeakPolarHBondContact O-CB 3.25Å; W431-F435 PolarHBondContact O-N 3.13Å
432	I	87.7	Confident	85.4	Confident	77 Å²	77	47.6 Å²	47.6	40%	0.395	23%	0.228	S	C	.	.	H	α-helix	trans	-60	-46	173.8	-66.4	166.3	0	0	0	110.2	T428 F429 L430 F435 I436	T428-I432 HydrophobicContact CG2-CD1 4.15Å; T428-I432 WeakPolarHBondContact O-CG1 3.32Å; T428-I432 PolarHBondContact O-N 2.91Å; F429-I432 PolarHBondContact O-N 3.24Å; L430-I432 VanDerWaalsContact C-N 3.34Å; I432-F435 PolarHBondContact O-N 3.34Å; I432-I436 HydrophobicContact CG2-CD1 3.73Å; I432-I436 HydrophobicContact CG2-CG1 4.45Å; I432-I436 VanDerWaalsContact O-CG1 3.25Å; I432-I436 WeakPolarHBondContact O-CG1 3.23Å; I432-I436 PolarHBondContact O-N 2.66Å
433	L	86.9	Confident	84.4	Confident	30 Å²	30	45.4 Å²	45.4	16%	0.157	22%	0.221	C	C	.	.	H	α-helix	trans	-61.8	-43.6	176.6	-78.1	166.7	0	0	0	112.5	F429 L430 W431 I436 S437 Y449 F452	F429-L433 HydrophobicContact CD1-CD1 3.92Å; F429-L433 HydrophobicContact CE1-CD1 3.32Å; F429-L433 HydrophobicContact CE1-CG 4.4Å; F429-L433 HydrophobicContact CE2-CD1 4.43Å; F429-L433 HydrophobicContact CZ-CD1 3.62Å; F429-L433 HydrophobicContact CZ-CG 4.36Å; F429-L433 PolarHBondContact O-N 3.31Å; L430-L433 HydrophobicContact CD2-CD1 4.34Å; L430-L433 PolarHBondContact O-N 2.8Å; W431-L433 VanDerWaalsContact C-N 3.33Å; W431-L433 PolarHBondContact O-N 3.45Å; L433-I436 PolarHBondContact O-N 3.35Å; L433-S437 VanDerWaalsContact O-CB 3.31Å; L433-S437 WeakPolarHBondContact O-CB 3.29Å; L433-S437 PolarHBondContact O-N 3.38Å; L433-Y449 HydrophobicContact CB-CD2 4.23Å; L433-F452 HydrophobicContact CD1-CB 3.96Å; L433-F452 HydrophobicContact CD1-CD1 4.43Å; L433-F452 HydrophobicContact CD1-CD2 3.57Å; L433-F452 HydrophobicContact CD1-CE2 4.17Å; L433-F452 HydrophobicContact CD1-CG 3.75Å
434	A	82.2	Confident	83.7	Confident	14 Å²	14	48 Å²	48	12%	0.116	24%	0.235	C	C	.	.	H	α-helix	trans	-62.9	-44.6	176.7	0	0	0	0	0	111.6	L430 W431 S437 N438 Y449	L430-A434 WeakPolarHBondContact O-CB 3.44Å; L430-A434 PolarHBondContact O-N 2.74Å; W431-A434 PolarHBondContact O-N 3.38Å; A434-S437 WeakPolarHBondContact O-CB 3.06Å; A434-S437 PolarHBondContact O-N 3.25Å; A434-N438 WeakPolarHBondContact O-CB 3.15Å; A434-N438 PolarHBondContact O-N 3.2Å; A434-N438 PolarHBondContact O-ND2 3.33Å; A434-Y449 HydrophobicContact CB-CD2 4.01Å; A434-Y449 HydrophobicContact CB-CE2 3.62Å
435	F	82.6	Confident	83.2	Confident	65 Å²	65	49.4 Å²	49.4	29%	0.285	24%	0.243	S	C	.	.	H	α-helix	trans	-60.8	-47.4	177.4	178.5	-105.3	0	0	0	111.1	H375 W431 I432 N438 Y439	H375-F435 HydrophobicContact CB-CD2 4.46Å; H375-F435 AromaticContact CD2-CD2 3.44Å; H375-F435 VanDerWaalsContact CD2-CD2 3.44Å; H375-F435 WeakPolarHBondContact CD2-CD2 3.47Å; H375-F435 AromaticContact CG-CD2 4Å; H375-F435 AromaticContact NE2-CD2 3.91Å; W431-F435 VanDerWaalsContact O-CB 3.3Å; W431-F435 WeakPolarHBondContact O-CB 3.25Å; W431-F435 PolarHBondContact O-N 3.13Å; I432-F435 PolarHBondContact O-N 3.34Å; F435-N438 PolarHBondContact O-N 2.9Å; F435-Y439 WeakPolarHBondContact O-CB 3.2Å; F435-Y439 PolarHBondContact O-N 2.89Å
436	I	83.3	Confident	82.5	Confident	69 Å²	69	44.9 Å²	44.9	35%	0.354	22%	0.218	S	C	.	.	H	α-helix	trans	-63.3	-43.6	176.9	-66.6	167.6	0	0	0	111	I432 L433 N438 Y439 I440 V445	I432-I436 HydrophobicContact CG2-CD1 3.73Å; I432-I436 HydrophobicContact CG2-CG1 4.45Å; I432-I436 VanDerWaalsContact O-CG1 3.25Å; I432-I436 WeakPolarHBondContact O-CG1 3.23Å; I432-I436 PolarHBondContact O-N 2.66Å; L433-I436 PolarHBondContact O-N 3.35Å; I436-N438 VanDerWaalsContact C-N 3.34Å; I436-N438 PolarHBondContact O-N 2.94Å; I436-Y439 PolarHBondContact O-N 3.05Å; I436-I440 HydrophobicContact CG2-CD1 3.63Å; I436-I440 HydrophobicContact CG2-CG1 4.35Å; I436-I440 WeakPolarHBondContact O-CG1 3.39Å; I436-I440 PolarHBondContact O-N 3.16Å; I436-V445 HydrophobicContact CG2-CG1 4.38Å
437	S	80	Confident	81.9	Confident	1 Å²	1	45.1 Å²	45.1	1%	0.007	22%	0.218	C	C	.	.	H	α-helix	trans	-57.2	-48.1	178.2	-177.8	0	0	0	0	111.9	Y355 L433 A434 C441 H442 W446	Y355-S437 PolarHBondContact OH-O 3.36Å; Y355-S437 PolarHBondContact OH-OG 3.01Å; L433-S437 VanDerWaalsContact O-CB 3.31Å; L433-S437 WeakPolarHBondContact O-CB 3.29Å; L433-S437 PolarHBondContact O-N 3.38Å; A434-S437 WeakPolarHBondContact O-CB 3.06Å; A434-S437 PolarHBondContact O-N 3.25Å; S437-C441 WeakPolarHBondContact O-CA 2.94Å; S437-C441 PolarHBondContact O-N 3.12Å; S437-H442 PolarHBondContact O-N 3.05Å; S437-W446 VanDerWaalsContact OG-CA 3.22Å; S437-W446 WeakPolarHBondContact OG-CA 3.16Å; S437-W446 WeakPolarHBondContact OG-CB 2.98Å; S437-W446 PolarHBondContact OG-N 3.26Å
438	N	76.4	Confident	81.7	Confident	17 Å²	17	50.1 Å²	50.1	9%	0.091	24%	0.24	C	C	.	.	H	α-helix	trans	-68.1	-50.9	178	-71.7	-30.2	0	0	0	109.9	Y355 G365 Q371 A434 F435 I436 I440 C441	Y355-N438 PolarHBondContact OH-OD1 2.96Å; G365-N438 CarbonylContact O-C 3.59Å; G365-N438 VanDerWaalsContact O-CA 3.29Å; G365-N438 WeakPolarHBondContact O-CA 3.4Å; G365-N438 WeakPolarHBondContact O-CB 3.44Å; Q371-N438 PolarHBondContact NE2-O 3Å; A434-N438 WeakPolarHBondContact O-CB 3.15Å; A434-N438 PolarHBondContact O-N 3.2Å; A434-N438 PolarHBondContact O-ND2 3.33Å; F435-N438 PolarHBondContact O-N 2.9Å; I436-N438 VanDerWaalsContact C-N 3.34Å; I436-N438 PolarHBondContact O-N 2.94Å; N438-I440 VanDerWaalsContact C-N 3.28Å; N438-I440 PolarHBondContact O-N 3.06Å; N438-I440 VanDerWaalsContact O-N 3.16Å; N438-C441 PolarHBondContact O-N 3.26Å; N438-C441 PolarHBondContact O-SG 2.71Å
439	Y	76.6	Confident	81.4	Confident	148 Å²	148	50.2 Å²	50.2	58%	0.58	24%	0.238	S	C	*	.	H	α-helix	trans	-54	-40.9	-178.7	-176.5	-100.8	0	0	0	113.8	F435 I436	F435-Y439 WeakPolarHBondContact O-CB 3.2Å; F435-Y439 PolarHBondContact O-N 2.89Å; I436-Y439 PolarHBondContact O-N 3.05Å
440	I	76.9	Confident	81	Confident	99 Å²	99	45.3 Å²	45.3	51%	0.508	22%	0.216	S	C	.	.	H	α-helix	trans	-88	-18.1	179.4	-53.5	174.9	0	0	0	112	I436 N438 H442	I436-I440 HydrophobicContact CG2-CD1 3.63Å; I436-I440 HydrophobicContact CG2-CG1 4.35Å; I436-I440 WeakPolarHBondContact O-CG1 3.39Å; I436-I440 PolarHBondContact O-N 3.16Å; N438-I440 VanDerWaalsContact C-N 3.28Å; N438-I440 PolarHBondContact O-N 3.06Å; N438-I440 VanDerWaalsContact O-N 3.16Å; I440-H442 VanDerWaalsContact C-N 3.34Å; I440-H442 HydrophobicContact CB-CB 4.39Å; I440-H442 HydrophobicContact CG2-CB 3.96Å; I440-H442 PolarHBondContact O-N 3.14Å
441	C	72.4	Confident	80.9	Confident	13 Å²	13	47.6 Å²	47.6	9%	0.088	23%	0.228	C	C	.	.	T	Hydrogen-bonded Turn	trans	53.9	45.7	-174.3	-85.4	0	0	0	0	114.8	N352 G365 C366 S437 N438	N352-C441 PolarHBondContact ND2-O 2.76Å; G365-C441 PolarHBondContact O-SG 2.92Å; G365-C441 VanDerWaalsContact O-SG 3.38Å; C366-C441 WeakPolarHBondContact CA-SG 2.97Å; C366-C441 HydrophobicContact CB-CB 4.07Å; C366-C441 WeakPolarHBondContact CB-SG 3.46Å; C366-C441 PolarHBondContact N-SG 3.43Å; C366-C441 WeakPolarHBondContact SG-CB 3.09Å; C366-C441 CovalentContact SG-SG 2Å; C366-C441 PolarHBondContact SG-SG 3.47Å; S437-C441 WeakPolarHBondContact O-CA 2.94Å; S437-C441 PolarHBondContact O-N 3.12Å; N438-C441 PolarHBondContact O-N 3.26Å; N438-C441 PolarHBondContact O-SG 2.71Å
442	H	73.2	Confident	81	Confident	70 Å²	70	48.2 Å²	48.2	32%	0.324	23%	0.232	S	C	.	.			trans	-111.8	117.6	-173	-163.7	-92.9	0	0	0	112.2	S437 I440 I444 V445 W446	S437-H442 PolarHBondContact O-N 3.05Å; I440-H442 VanDerWaalsContact C-N 3.34Å; I440-H442 HydrophobicContact CB-CB 4.39Å; I440-H442 HydrophobicContact CG2-CB 3.96Å; I440-H442 PolarHBondContact O-N 3.14Å; H442-I444 VanDerWaalsContact C-N 3.3Å; H442-I444 PolarHBondContact ND1-N 3.4Å; H442-I444 PolarHBondContact O-N 2.76Å; H442-V445 HydrophobicContact CB-CB 4.41Å; H442-V445 HydrophobicContact CB-CG2 3.98Å; H442-V445 PolarHBondContact O-N 3.08Å; H442-W446 PolarHBondContact O-N 2.99Å
443	T	69.9	Low	81.1	Confident	28 Å²	28	44.6 Å²	44.6	17%	0.172	21%	0.214	C	C	.	.	H	α-helix	trans	-55.8	-39.5	-176.3	-56.8	0	0	0	0	113.5	I358 V445 W446 Q447	I358-T443 HydrophobicContact CD1-CG2 3.3Å; T443-V445 VanDerWaalsContact C-N 3.33Å; T443-V445 PolarHBondContact O-N 3.38Å; T443-W446 WeakPolarHBondContact O-CB 3.39Å; T443-W446 PolarHBondContact O-N 2.89Å; T443-Q447 WeakPolarHBondContact O-CG 3.16Å; T443-Q447 PolarHBondContact O-N 2.94Å
444	I	77.4	Confident	81.2	Confident	56 Å²	56	44.1 Å²	44.1	29%	0.287	21%	0.214	S	C	.	.	H	α-helix	trans	-65.5	-38.5	-179.8	-55	-174.8	0	0	0	110.9	L26 H442 W446 Q447 F448	L26-I444 HydrophobicContact CD2-CD1 4.16Å; H442-I444 VanDerWaalsContact C-N 3.3Å; H442-I444 PolarHBondContact ND1-N 3.4Å; H442-I444 PolarHBondContact O-N 2.76Å; I444-W446 VanDerWaalsContact C-N 3.3Å; I444-W446 PolarHBondContact O-N 3.08Å; I444-Q447 PolarHBondContact O-N 3.3Å; I444-F448 HydrophobicContact CG2-CD2 3.85Å; I444-F448 HydrophobicContact CG2-CE2 3.57Å; I444-F448 WeakPolarHBondContact O-CD2 3.43Å; I444-F448 PolarHBondContact O-N 2.95Å
445	V	81.1	Confident	81.7	Confident	33 Å²	33	47.8 Å²	47.8	20%	0.2	23%	0.231	C	C	.	.	H	α-helix	trans	-68.1	-36.8	178.9	-175.1	0	0	0	0	109.9	I436 H442 T443 F448 Y449	I436-V445 HydrophobicContact CG2-CG1 4.38Å; H442-V445 HydrophobicContact CB-CB 4.41Å; H442-V445 HydrophobicContact CB-CG2 3.98Å; H442-V445 PolarHBondContact O-N 3.08Å; T443-V445 VanDerWaalsContact C-N 3.33Å; T443-V445 PolarHBondContact O-N 3.38Å; V445-F448 PolarHBondContact O-N 2.87Å; V445-Y449 PolarHBondContact O-N 2.95Å
446	W	78.4	Confident	82.2	Confident	14 Å²	14	45.3 Å²	45.3	5%	0.053	22%	0.221	C	C	.	.	H	α-helix	trans	-64.2	-40.6	173.7	-176.2	88.7	0	0	0	112.6	A91 M95 A142 Y355 I358 T359 S437 H442 T443 I444 Y449 G450	A91-W446 HydrophobicContact CB-CZ3 4.37Å; M95-W446 HydrophobicContact CE-CH2 3.71Å; M95-W446 HydrophobicContact CE-CZ2 4.08Å; A142-W446 HydrophobicContact CB-CH2 3.54Å; A142-W446 HydrophobicContact CB-CZ2 3.71Å; Y355-W446 HydrophobicContact CE2-CB 3.87Å; Y355-W446 HydrophobicContact CE2-CG 4.35Å; I358-W446 HydrophobicContact CG2-CD2 4.04Å; I358-W446 HydrophobicContact CG2-CE3 3.46Å; I358-W446 VanDerWaalsContact CG2-CE3 3.46Å; I358-W446 HydrophobicContact CG2-CH2 3.63Å; I358-W446 HydrophobicContact CG2-CZ2 4.17Å; I358-W446 HydrophobicContact CG2-CZ3 3.24Å; T359-W446 HydrophobicContact CG2-CD2 4.2Å; T359-W446 HydrophobicContact CG2-CG 4.07Å; S437-W446 VanDerWaalsContact OG-CA 3.22Å; S437-W446 WeakPolarHBondContact OG-CA 3.16Å; S437-W446 WeakPolarHBondContact OG-CB 2.98Å; S437-W446 PolarHBondContact OG-N 3.26Å; H442-W446 PolarHBondContact O-N 2.99Å; T443-W446 WeakPolarHBondContact O-CB 3.39Å; T443-W446 PolarHBondContact O-N 2.89Å; I444-W446 VanDerWaalsContact C-N 3.3Å; I444-W446 PolarHBondContact O-N 3.08Å; W446-Y449 WeakPolarHBondContact O-CB 3.46Å; W446-Y449 PolarHBondContact O-N 3.26Å; W446-G450 PolarHBondContact O-N 2.05Å
447	Q	80.6	Confident	82.6	Confident	17 Å²	17	42.1 Å²	42.1	8%	0.079	20%	0.204	C	C	.	.	H	α-helix	trans	-63.5	-42.4	174.4	-71.8	172.9	-9.2	0	0	111.7	A91 T443 I444 Y449 G450 I451	A91-Q447 HydrophobicContact CB-CB 4.44Å; A91-Q447 HydrophobicContact CB-CG 4.48Å; T443-Q447 WeakPolarHBondContact O-CG 3.16Å; T443-Q447 PolarHBondContact O-N 2.94Å; I444-Q447 PolarHBondContact O-N 3.3Å; Q447-Y449 VanDerWaalsContact C-N 3.32Å; Q447-Y449 PolarHBondContact O-N 2.64Å; Q447-G450 PolarHBondContact O-N 3.14Å; Q447-I451 WeakPolarHBondContact O-CG1 3.48Å; Q447-I451 PolarHBondContact O-N 3Å
448	F	86.1	Confident	83.1	Confident	111 Å²	111	46.7 Å²	46.7	49%	0.487	23%	0.228	S	C	.	.	H	α-helix	trans	-58.9	-44.5	172.1	-81.9	-63	0	0	0	111.4	I444 V445 G450 I451 F452	I444-F448 HydrophobicContact CG2-CD2 3.85Å; I444-F448 HydrophobicContact CG2-CE2 3.57Å; I444-F448 WeakPolarHBondContact O-CD2 3.43Å; I444-F448 PolarHBondContact O-N 2.95Å; V445-F448 PolarHBondContact O-N 2.87Å; F448-G450 VanDerWaalsContact C-N 3.33Å; F448-G450 PolarHBondContact O-N 3.16Å; F448-I451 PolarHBondContact O-N 2.91Å; F448-I451 VanDerWaalsContact O-N 3.15Å; F448-F452 HydrophobicContact CB-CD2 4.35Å; F448-F452 HydrophobicContact CB-CE2 4.39Å; F448-F452 HydrophobicContact CD1-CE2 4.48Å; F448-F452 WeakPolarHBondContact O-CD2 3.37Å; F448-F452 PolarHBondContact O-N 2.81Å
449	Y	86	Confident	83.8	Confident	26 Å²	26	50.6 Å²	50.6	10%	0.102	24%	0.242	C	C	.	.	H	α-helix	trans	-55.7	-45.8	174.1	169	-107.4	0	0	0	112	L138 L430 L433 A434 V445 W446 Q447 I451 F452 I453	L138-Y449 HydrophobicContact CD1-CE1 4.22Å; L430-Y449 HydrophobicContact CB-CE2 4.32Å; L433-Y449 HydrophobicContact CB-CD2 4.23Å; A434-Y449 HydrophobicContact CB-CD2 4.01Å; A434-Y449 HydrophobicContact CB-CE2 3.62Å; V445-Y449 PolarHBondContact O-N 2.95Å; W446-Y449 WeakPolarHBondContact O-CB 3.46Å; W446-Y449 PolarHBondContact O-N 3.26Å; Q447-Y449 VanDerWaalsContact C-N 3.32Å; Q447-Y449 PolarHBondContact O-N 2.64Å; Y449-I451 VanDerWaalsContact C-N 3.33Å; Y449-I451 PolarHBondContact O-N 3.37Å; Y449-F452 PolarHBondContact O-N 3.06Å; Y449-I453 HydrophobicContact CD1-CD1 3.82Å; Y449-I453 HydrophobicContact CD2-CD1 4.37Å; Y449-I453 HydrophobicContact CD2-CG1 4.45Å; Y449-I453 HydrophobicContact CE1-CD1 3.32Å; Y449-I453 HydrophobicContact CE1-CG1 4.32Å; Y449-I453 HydrophobicContact CE2-CD1 3.91Å; Y449-I453 HydrophobicContact CE2-CG1 4.02Å; Y449-I453 HydrophobicContact CG-CD1 4.33Å; Y449-I453 WeakPolarHBondContact O-CG1 3.39Å; Y449-I453 PolarHBondContact O-N 3.07Å
450	G	83.9	Confident	84.4	Confident	0 Å²	0	43.6 Å²	43.6	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-59.7	-37.5	175	0	0	0	0	0	114.2	S94 W446 Q447 F448	S94-G450 PolarHBondContact OG-O 2.72Å; W446-G450 PolarHBondContact O-N 2.05Å; Q447-G450 PolarHBondContact O-N 3.14Å; F448-G450 VanDerWaalsContact C-N 3.33Å; F448-G450 PolarHBondContact O-N 3.16Å
451	I	88.2	Confident	85	Confident	61 Å²	61	40.2 Å²	40.2	31%	0.313	20%	0.198	S	C	.	.	H	α-helix	trans	-69.2	-45.1	174.1	-65.6	167.2	0	0	0	110.6	Q447 F448 Y449 I453 A454 L455	Q447-I451 WeakPolarHBondContact O-CG1 3.48Å; Q447-I451 PolarHBondContact O-N 3Å; F448-I451 PolarHBondContact O-N 2.91Å; F448-I451 VanDerWaalsContact O-N 3.15Å; Y449-I451 VanDerWaalsContact C-N 3.33Å; Y449-I451 PolarHBondContact O-N 3.37Å; I451-I453 VanDerWaalsContact C-N 3.29Å; I451-I453 PolarHBondContact O-N 3.43Å; I451-A454 WeakPolarHBondContact O-CB 3.09Å; I451-A454 PolarHBondContact O-N 2.96Å; I451-A454 VanDerWaalsContact O-N 3.1Å; I451-L455 HydrophobicContact CG2-CD1 4.3Å; I451-L455 PolarHBondContact O-N 3.32Å; I451-L455 VanDerWaalsContact O-N 3.09Å
452	F	92.1	Very high	85.7	Confident	64 Å²	64	42 Å²	42	28%	0.281	21%	0.208	S	C	.	.	H	α-helix	trans	-64.9	-31.3	179.6	-81.5	-68.9	0	0	0	112.5	F429 L430 L433 F448 Y449 A454 L455 Q456	F429-F452 AromaticContact CE1-CD1 3.72Å; F429-F452 HydrophobicContact CE1-CD1 3.72Å; F429-F452 AromaticContact CE1-CE1 3.95Å; F429-F452 HydrophobicContact CE1-CE1 3.95Å; F429-F452 HydrophobicContact CE1-CG 4.16Å; F429-F452 HydrophobicContact CZ-CD1 4.33Å; F429-F452 HydrophobicContact CZ-CE1 4.12Å; F429-F452 HydrophobicContact CZ-CZ 4.44Å; L430-F452 HydrophobicContact CD2-CB 3.56Å; L433-F452 HydrophobicContact CD1-CB 3.96Å; L433-F452 HydrophobicContact CD1-CD1 4.43Å; L433-F452 HydrophobicContact CD1-CD2 3.57Å; L433-F452 HydrophobicContact CD1-CE2 4.17Å; L433-F452 HydrophobicContact CD1-CG 3.75Å; F448-F452 HydrophobicContact CB-CD2 4.35Å; F448-F452 HydrophobicContact CB-CE2 4.39Å; F448-F452 HydrophobicContact CD1-CE2 4.48Å; F448-F452 WeakPolarHBondContact O-CD2 3.37Å; F448-F452 PolarHBondContact O-N 2.81Å; Y449-F452 PolarHBondContact O-N 3.06Å; F452-A454 VanDerWaalsContact C-N 3.3Å; F452-A454 PolarHBondContact O-N 3.14Å; F452-L455 HydrophobicContact CD1-CD1 4.11Å; F452-L455 HydrophobicContact CE1-CD1 4.37Å; F452-L455 PolarHBondContact O-N 3.19Å; F452-Q456 VanDerWaalsContact O-CB 3.25Å; F452-Q456 WeakPolarHBondContact O-CB 3.27Å; F452-Q456 PolarHBondContact O-N 3.4Å
453	I	89.6	Confident	86.3	Confident	1 Å²	1	39.3 Å²	39.3	1%	0.005	20%	0.197	C	C	.	.	H	α-helix	trans	-57.3	-43.8	170.7	-75.7	162.7	0	0	0	111.5	M95 A98 N135 L138 L430 Y449 I451 Q456 S457	M95-I453 HydrophobicContact SD-CD1 4.47Å; A98-I453 HydrophobicContact CB-CG2 4.09Å; N135-I453 HydrophobicContact CB-CG2 4.43Å; N135-I453 WeakPolarHBondContact OD1-CG2 3.12Å; L138-I453 HydrophobicContact CD1-CD1 3.61Å; L430-I453 HydrophobicContact CD1-CG1 3.9Å; Y449-I453 HydrophobicContact CD1-CD1 3.82Å; Y449-I453 HydrophobicContact CD2-CD1 4.37Å; Y449-I453 HydrophobicContact CD2-CG1 4.45Å; Y449-I453 HydrophobicContact CE1-CD1 3.32Å; Y449-I453 HydrophobicContact CE1-CG1 4.32Å; Y449-I453 HydrophobicContact CE2-CD1 3.91Å; Y449-I453 HydrophobicContact CE2-CG1 4.02Å; Y449-I453 HydrophobicContact CG-CD1 4.33Å; Y449-I453 WeakPolarHBondContact O-CG1 3.39Å; Y449-I453 PolarHBondContact O-N 3.07Å; I451-I453 VanDerWaalsContact C-N 3.29Å; I451-I453 PolarHBondContact O-N 3.43Å; I453-Q456 PolarHBondContact O-N 3.17Å; I453-S457 PolarHBondContact O-N 3Å; I453-S457 PolarHBondContact O-OG 3.34Å
454	A	89	Confident	87	Confident	20 Å²	20	38 Å²	38	17%	0.165	19%	0.189	C	C	.	.	H	α-helix	trans	-68.1	-43.6	178.9	0	0	0	0	0	111.9	S94 A98 I451 F452 Q456 S457 L458	S94-A454 WeakPolarHBondContact O-CB 3.34Å; A98-A454 HydrophobicContact CB-CB 4.27Å; I451-A454 WeakPolarHBondContact O-CB 3.09Å; I451-A454 PolarHBondContact O-N 2.96Å; I451-A454 VanDerWaalsContact O-N 3.1Å; F452-A454 VanDerWaalsContact C-N 3.3Å; F452-A454 PolarHBondContact O-N 3.14Å; A454-Q456 VanDerWaalsContact C-N 3.29Å; A454-Q456 PolarHBondContact O-N 2.82Å; A454-S457 PolarHBondContact O-N 2.88Å; A454-L458 WeakPolarHBondContact O-CB 3.36Å; A454-L458 PolarHBondContact O-N 3.32Å
455	L	92.1	Very high	87.2	Confident	91 Å²	91	36.7 Å²	36.7	48%	0.476	18%	0.184	S	C	.	.	H	α-helix	trans	-61.8	-38.3	174.2	-68.9	175.2	0	0	0	112	I451 F452 L458 Y459	I451-L455 HydrophobicContact CG2-CD1 4.3Å; I451-L455 PolarHBondContact O-N 3.32Å; I451-L455 VanDerWaalsContact O-N 3.09Å; F452-L455 HydrophobicContact CD1-CD1 4.11Å; F452-L455 HydrophobicContact CE1-CD1 4.37Å; F452-L455 PolarHBondContact O-N 3.19Å; L455-L458 PolarHBondContact O-N 3.44Å; L455-Y459 VanDerWaalsContact O-CB 3.27Å; L455-Y459 WeakPolarHBondContact O-CB 3.3Å; L455-Y459 PolarHBondContact O-N 3.49Å
456	Q	93.4	Very high	86.8	Confident	13 Å²	13	39.8 Å²	39.8	6%	0.061	19%	0.194	C	C	.	.	H	α-helix	trans	-65.9	-44.3	177.3	-166.1	-142.4	33	0	0	111.3	S426 H427 L430 F452 I453 A454 Y459 I460	S426-Q456 PolarHBondContact O-NE2 2.91Å; S426-Q456 PolarHBondContact OG-NE2 3.36Å; S426-Q456 VanDerWaalsContact OG-NE2 3.15Å; H427-Q456 PolarHBondContact CE1-NE2 3.1Å; H427-Q456 VanDerWaalsContact CE1-NE2 3.28Å; H427-Q456 PolarHBondContact ND1-NE2 3.08Å; H427-Q456 VanDerWaalsContact ND1-NE2 3.13Å; L430-Q456 HydrophobicContact CD1-CB 3.76Å; L430-Q456 HydrophobicContact CD1-CG 3.8Å; L430-Q456 HydrophobicContact CD2-CB 4.44Å; L430-Q456 HydrophobicContact CG-CB 4.2Å; L430-Q456 HydrophobicContact CG-CG 4.11Å; F452-Q456 VanDerWaalsContact O-CB 3.25Å; F452-Q456 WeakPolarHBondContact O-CB 3.27Å; F452-Q456 PolarHBondContact O-N 3.4Å; I453-Q456 PolarHBondContact O-N 3.17Å; A454-Q456 VanDerWaalsContact C-N 3.29Å; A454-Q456 PolarHBondContact O-N 2.82Å; Q456-Y459 WeakPolarHBondContact O-CB 3.11Å; Q456-Y459 PolarHBondContact O-N 2.91Å; Q456-I460 HydrophobicContact CG-CD1 4.3Å; Q456-I460 VanDerWaalsContact O-CG1 3.29Å; Q456-I460 WeakPolarHBondContact O-CG1 3.26Å; Q456-I460 PolarHBondContact O-N 2.89Å
457	S	91.3	Very high	86.6	Confident	1 Å²	1	40.1 Å²	40.1	1%	0.007	20%	0.199	C	C	.	.	H	α-helix	trans	-62.1	-45	176.6	-62.3	0	0	0	0	111.1	N135 I453 A454 Y459 I460 I461	N135-S457 PolarHBondContact ND2-OG 2.96Å; N135-S457 VanDerWaalsContact ND2-OG 3.11Å; I453-S457 PolarHBondContact O-N 3Å; I453-S457 PolarHBondContact O-OG 3.34Å; A454-S457 PolarHBondContact O-N 2.88Å; S457-Y459 PolarHBondContact O-N 2.86Å; S457-I460 PolarHBondContact O-N 2.89Å; S457-I461 VanDerWaalsContact O-CG1 3.29Å; S457-I461 WeakPolarHBondContact O-CG1 3.47Å; S457-I461 PolarHBondContact O-N 3.36Å
458	L	90.5	Very high	85.8	Confident	98 Å²	98	46.3 Å²	46.3	51%	0.513	22%	0.221	S	C	.	.	H	α-helix	trans	-60	-46.1	173.6	-174.6	68.7	0	0	0	111.5	A454 L455 I460 I461 V462	A454-L458 WeakPolarHBondContact O-CB 3.36Å; A454-L458 PolarHBondContact O-N 3.32Å; L455-L458 PolarHBondContact O-N 3.44Å; L458-I460 VanDerWaalsContact C-N 3.33Å; L458-I460 PolarHBondContact O-N 3.19Å; L458-I461 PolarHBondContact O-N 2.97Å; L458-V462 HydrophobicContact CD1-CG2 4.17Å; L458-V462 HydrophobicContact CG-CG2 4.25Å; L458-V462 WeakPolarHBondContact O-CB 3.42Å; L458-V462 VanDerWaalsContact O-CG2 3.25Å; L458-V462 WeakPolarHBondContact O-CG2 3.25Å; L458-V462 PolarHBondContact O-N 2.99Å
459	Y	91.6	Very high	84.8	Confident	98 Å²	98	42.1 Å²	42.1	38%	0.384	21%	0.206	S	C	.	.	H	α-helix	trans	-58.2	-42.7	177.2	167.2	-102.2	0	0	0	112.4	K422 L455 Q456 S457 S463	K422-Y459 HydrophobicContact CB-CE1 4.26Å; K422-Y459 WeakPolarHBondContact CG-OH 2.98Å; L455-Y459 VanDerWaalsContact O-CB 3.27Å; L455-Y459 WeakPolarHBondContact O-CB 3.3Å; L455-Y459 PolarHBondContact O-N 3.49Å; Q456-Y459 WeakPolarHBondContact O-CB 3.11Å; Q456-Y459 PolarHBondContact O-N 2.91Å; S457-Y459 PolarHBondContact O-N 2.86Å; Y459-S463 WeakPolarHBondContact CE2-OG 3.31Å; Y459-S463 WeakPolarHBondContact O-CB 3.42Å; Y459-S463 PolarHBondContact O-N 2.89Å; Y459-S463 PolarHBondContact O-OG 2.59Å
460	I	89	Confident	83.9	Confident	1 Å²	1	41.2 Å²	41.2	1%	0.005	20%	0.202	C	C	.	.	H	α-helix	trans	-64.2	-50.2	177.7	-69.1	165.8	0	0	0	110	M102 I423 Q456 S457 L458 S463 F464	M102-I460 HydrophobicContact CE-CG2 4.19Å; M102-I460 HydrophobicContact SD-CG2 4.33Å; I423-I460 HydrophobicContact CD1-CG2 4.4Å; I423-I460 HydrophobicContact CG1-CD1 4.23Å; I423-I460 HydrophobicContact CG1-CG1 4.17Å; I423-I460 HydrophobicContact CG1-CG2 4.36Å; Q456-I460 HydrophobicContact CG-CD1 4.3Å; Q456-I460 VanDerWaalsContact O-CG1 3.29Å; Q456-I460 WeakPolarHBondContact O-CG1 3.26Å; Q456-I460 PolarHBondContact O-N 2.89Å; S457-I460 PolarHBondContact O-N 2.89Å; L458-I460 VanDerWaalsContact C-N 3.33Å; L458-I460 PolarHBondContact O-N 3.19Å; I460-S463 PolarHBondContact O-N 3.49Å; I460-F464 HydrophobicContact CG2-CD2 3.99Å; I460-F464 HydrophobicContact CG2-CE2 3.94Å; I460-F464 HydrophobicContact CG2-CG 4.36Å; I460-F464 HydrophobicContact CG2-CZ 4.23Å; I460-F464 VanDerWaalsContact O-CB 3.24Å; I460-F464 WeakPolarHBondContact O-CB 3.37Å; I460-F464 WeakPolarHBondContact O-CD1 3.26Å; I460-F464 VanDerWaalsContact O-CG 3.23Å; I460-F464 WeakPolarHBondContact O-CG 3.13Å; I460-F464 PolarHBondContact O-N 3.11Å
461	I	89	Confident	83.2	Confident	29 Å²	29	41.9 Å²	41.9	15%	0.149	21%	0.206	C	C	.	.	H	α-helix	trans	-60.3	-51.5	-179.3	-65.9	167.3	0	0	0	110.3	M102 H105 S457 L458 S463 F464 T465	M102-I461 HydrophobicContact CG-CD1 4.39Å; M102-I461 HydrophobicContact SD-CD1 3.98Å; M102-I461 HydrophobicContact SD-CG1 3.74Å; H105-I461 HydrophobicContact CB-CD1 4.42Å; H105-I461 HydrophobicContact CB-CG1 4.1Å; S457-I461 VanDerWaalsContact O-CG1 3.29Å; S457-I461 WeakPolarHBondContact O-CG1 3.47Å; S457-I461 PolarHBondContact O-N 3.36Å; L458-I461 PolarHBondContact O-N 2.97Å; I461-S463 PolarHBondContact O-N 2.78Å; I461-F464 PolarHBondContact O-N 2.82Å; I461-T465 WeakPolarHBondContact O-CB 3.12Å; I461-T465 PolarHBondContact O-N 2.93Å; I461-T465 PolarHBondContact O-OG1 3.37Å
462	V	87.4	Confident	82.2	Confident	50 Å²	50	41.2 Å²	41.2	30%	0.303	20%	0.201	S	C	.	.	H	α-helix	trans	-60	-49.1	178.7	171.5	0	0	0	0	110	L458 F464 F466	L458-V462 HydrophobicContact CD1-CG2 4.17Å; L458-V462 HydrophobicContact CG-CG2 4.25Å; L458-V462 WeakPolarHBondContact O-CB 3.42Å; L458-V462 VanDerWaalsContact O-CG2 3.25Å; L458-V462 WeakPolarHBondContact O-CG2 3.25Å; L458-V462 PolarHBondContact O-N 2.99Å; V462-F464 PolarHBondContact O-N 3.06Å; V462-F464 VanDerWaalsContact O-N 3.15Å; V462-F466 HydrophobicContact CB-CD2 4.24Å; V462-F466 HydrophobicContact CG1-CD2 3.67Å; V462-F466 HydrophobicContact CG1-CE2 4.07Å; V462-F466 HydrophobicContact CG2-CE2 4.47Å; V462-F466 WeakPolarHBondContact O-CB 3.49Å; V462-F466 VanDerWaalsContact O-CD2 3.28Å; V462-F466 WeakPolarHBondContact O-CD2 3.5Å; V462-F466 PolarHBondContact O-N 3.45Å
463	S	85.5	Confident	81	Confident	13 Å²	13	39.8 Å²	39.8	9%	0.091	20%	0.198	C	C	.	.	H	α-helix	trans	-59.2	-30.5	180	-79.7	0	0	0	0	113.8	K422 Y459 I460 I461	K422-S463 PolarHBondContact NZ-OG 2.87Å; Y459-S463 WeakPolarHBondContact CE2-OG 3.31Å; Y459-S463 WeakPolarHBondContact O-CB 3.42Å; Y459-S463 PolarHBondContact O-N 2.89Å; Y459-S463 PolarHBondContact O-OG 2.59Å; I460-S463 PolarHBondContact O-N 3.49Å; I461-S463 PolarHBondContact O-N 2.78Å
464	F	85.1	Confident	79.8	Confident	1 Å²	1	44 Å²	44	0%	0.004	22%	0.22	C	C	.	.	H	α-helix	trans	-94.8	-46	-173.2	-75.1	15.6	0	0	0	111.5	Y120 L124 I128 M419 I423 I460 I461 V462 S467 F470	Y120-F464 AromaticContact CE1-CD2 3.82Å; Y120-F464 HydrophobicContact CE1-CD2 3.82Å; Y120-F464 HydrophobicContact CE1-CE2 4.37Å; Y120-F464 WeakPolarHBondContact OH-CB 3.31Å; L124-F464 HydrophobicContact CD1-CE2 4.02Å; L124-F464 HydrophobicContact CD1-CZ 4.3Å; L124-F464 HydrophobicContact CD2-CE2 4.07Å; L124-F464 HydrophobicContact CG-CE2 4.29Å; I128-F464 HydrophobicContact CD1-CD2 4.5Å; I128-F464 HydrophobicContact CD1-CE2 4.48Å; M419-F464 HydrophobicContact CB-CD1 4.35Å; M419-F464 HydrophobicContact CB-CE1 3.6Å; M419-F464 HydrophobicContact CB-CE2 4.13Å; M419-F464 HydrophobicContact CB-CZ 3.43Å; M419-F464 VanDerWaalsContact CB-CZ 3.43Å; M419-F464 HydrophobicContact CG-CD1 3.84Å; M419-F464 HydrophobicContact CG-CE1 3.6Å; M419-F464 HydrophobicContact CG-CE2 4.28Å; M419-F464 HydrophobicContact CG-CG 4.31Å; M419-F464 HydrophobicContact CG-CZ 3.8Å; M419-F464 WeakPolarHBondContact O-CZ 3.28Å; I423-F464 HydrophobicContact CD1-CE1 4.49Å; I423-F464 HydrophobicContact CD1-CE2 3.56Å; I423-F464 HydrophobicContact CD1-CZ 3.33Å; I423-F464 HydrophobicContact CG1-CE1 4.31Å; I423-F464 HydrophobicContact CG1-CE2 4.22Å; I423-F464 HydrophobicContact CG1-CZ 3.54Å; I460-F464 HydrophobicContact CG2-CD2 3.99Å; I460-F464 HydrophobicContact CG2-CE2 3.94Å; I460-F464 HydrophobicContact CG2-CG 4.36Å; I460-F464 HydrophobicContact CG2-CZ 4.23Å; I460-F464 VanDerWaalsContact O-CB 3.24Å; I460-F464 WeakPolarHBondContact O-CB 3.37Å; I460-F464 WeakPolarHBondContact O-CD1 3.26Å; I460-F464 VanDerWaalsContact O-CG 3.23Å; I460-F464 WeakPolarHBondContact O-CG 3.13Å; I460-F464 PolarHBondContact O-N 3.11Å; I461-F464 PolarHBondContact O-N 2.82Å; V462-F464 PolarHBondContact O-N 3.06Å; V462-F464 VanDerWaalsContact O-N 3.15Å; F464-S467 VanDerWaalsContact O-CB 3.24Å; F464-S467 WeakPolarHBondContact O-CB 3.2Å; F464-S467 PolarHBondContact O-N 3.22Å; F464-S467 VanDerWaalsContact O-N 3.11Å; F464-S467 PolarHBondContact O-OG 2.91Å; F464-F470 WeakPolarHBondContact O-CB 3.28Å
465	T	81	Confident	78.7	Confident	29 Å²	29	47 Å²	47	18%	0.178	23%	0.229	C	C	.	.	H	α-helix	trans	-65.7	-39	178.2	-58.5	0	0	0	0	111.5	H105 I461 S467 F470 L471	H105-T465 PolarHBondContact CE1-OG1 2.85Å; I461-T465 WeakPolarHBondContact O-CB 3.12Å; I461-T465 PolarHBondContact O-N 2.93Å; I461-T465 PolarHBondContact O-OG1 3.37Å; T465-S467 VanDerWaalsContact C-N 3.26Å; T465-S467 PolarHBondContact O-N 2.92Å; T465-F470 HydrophobicContact CG2-CD1 4.11Å; T465-F470 HydrophobicContact CG2-CE1 3.75Å; T465-F470 HydrophobicContact CG2-CZ 4.31Å; T465-F470 WeakPolarHBondContact O-CD1 3.34Å; T465-L471 WeakPolarHBondContact O-CD2 3.37Å; T465-L471 WeakPolarHBondContact O-CG 3.11Å
466	F	73.7	Confident	77	Confident	97 Å²	97	50 Å²	50	43%	0.425	24%	0.238	S	C	.	.	T	Hydrogen-bonded Turn	trans	-85.7	6.4	174.3	-65.4	-72.9	0	0	0	113.5	V462 R468 L489 L493	V462-F466 HydrophobicContact CB-CD2 4.24Å; V462-F466 HydrophobicContact CG1-CD2 3.67Å; V462-F466 HydrophobicContact CG1-CE2 4.07Å; V462-F466 HydrophobicContact CG2-CE2 4.47Å; V462-F466 WeakPolarHBondContact O-CB 3.49Å; V462-F466 VanDerWaalsContact O-CD2 3.28Å; V462-F466 WeakPolarHBondContact O-CD2 3.5Å; V462-F466 PolarHBondContact O-N 3.45Å; F466-R468 PolarHBondContact O-N 2.79Å; F466-L489 HydrophobicContact CD1-CD2 4.49Å; F466-L489 HydrophobicContact CE1-CD2 4.49Å; F466-L493 HydrophobicContact CB-CD1 4.45Å; F466-L493 HydrophobicContact CD1-CD1 4.31Å
467	S	72.7	Confident	75.1	Confident	21 Å²	21	56.4 Å²	56.4	15%	0.147	26%	0.262	C	S	.	.	S	Bend	trans	-68.5	134.3	171.1	75.8	0	0	0	0	109.5	M419 F464 T465 P469 F470 L471	M419-S467 WeakPolarHBondContact CE-OG 3.45Å; F464-S467 VanDerWaalsContact O-CB 3.24Å; F464-S467 WeakPolarHBondContact O-CB 3.2Å; F464-S467 PolarHBondContact O-N 3.22Å; F464-S467 VanDerWaalsContact O-N 3.11Å; F464-S467 PolarHBondContact O-OG 2.91Å; T465-S467 VanDerWaalsContact C-N 3.26Å; T465-S467 PolarHBondContact O-N 2.92Å; S467-P469 VanDerWaalsContact C-N 3.32Å; S467-F470 WeakPolarHBondContact O-CA 3.06Å; S467-F470 WeakPolarHBondContact O-CB 3.07Å; S467-F470 PolarHBondContact O-N 3.22Å; S467-F470 WeakPolarHBondContact OG-CB 3.09Å; S467-L471 PolarHBondContact O-N 2.69Å
468	R	64.2	Low	73.2	Confident	147 Å²	147	63.4 Å²	63.4	56%	0.555	30%	0.299	S	S	*	.	H	α-helix	trans	-43.5	-47.7	176.3	-173.8	175	179.8	155.3	13.9	114.2	F466 F470 L471 E472	F466-R468 PolarHBondContact O-N 2.79Å; R468-F470 VanDerWaalsContact C-N 3.32Å; R468-F470 PolarHBondContact O-N 3.06Å; R468-L471 PolarHBondContact O-N 3.04Å; R468-E472 HydrophobicContact CG-CG 4.17Å; R468-E472 VanDerWaalsContact CG-OE1 3.31Å; R468-E472 WeakPolarHBondContact CG-OE1 3.35Å; R468-E472 IonicContact CZ-OE1 3.69Å; R468-E472 IonicContact NE-OE1 2.79Å; R468-E472 PolarHBondContact NE-OE1 2.69Å; R468-E472 IonicContact NH2-OE1 3.76Å; R468-E472 WeakPolarHBondContact O-CB 3.49Å; R468-E472 VanDerWaalsContact O-CG 3.29Å; R468-E472 WeakPolarHBondContact O-CG 3.05Å; R468-E472 PolarHBondContact O-N 3.34Å
469	P	66.6	Low	71.3	Confident	24 Å²	24	63.1 Å²	63.1	16%	0.156	30%	0.299	C	S	.	.	H	α-helix	trans	-67.5	-30.6	179.6	27.8	-37.1	0	0	0	113.3	L119 A415 S467 V473	L119-P469 HydrophobicContact CD1-CB 4.14Å; L119-P469 HydrophobicContact CD2-CB 3.88Å; L119-P469 HydrophobicContact CD2-CG 4.22Å; A415-P469 HydrophobicContact CB-CB 4.44Å; A415-P469 HydrophobicContact CB-CG 3.65Å; S467-P469 VanDerWaalsContact C-N 3.32Å; P469-V473 WeakPolarHBondContact O-CB 3.42Å; P469-V473 WeakPolarHBondContact O-CG2 3.48Å; P469-V473 PolarHBondContact O-N 3.5Å; P469-V473 VanDerWaalsContact O-N 3.14Å
470	F	67.1	Low	69.2	Low	6 Å²	6	62.8 Å²	62.8	3%	0.026	31%	0.308	C	S	.	.	H	α-helix	trans	-66.5	-48.7	173.7	-171.5	-78.6	0	0	0	110.4	V109 L116 Y120 F464 T465 S467 R468 V473 L474	V109-F470 HydrophobicContact CG2-CE2 4.4Å; L116-F470 HydrophobicContact CD1-CE2 3.94Å; L116-F470 HydrophobicContact CD1-CZ 4.01Å; L116-F470 HydrophobicContact CD2-CD2 3.54Å; L116-F470 HydrophobicContact CD2-CE2 3.76Å; L116-F470 HydrophobicContact CD2-CG 4.01Å; L116-F470 HydrophobicContact CD2-CZ 4.38Å; L116-F470 HydrophobicContact CG-CE2 4.46Å; Y120-F470 AromaticContact CE2-CD2 3.94Å; Y120-F470 HydrophobicContact CE2-CD2 3.94Å; Y120-F470 HydrophobicContact CE2-CE2 4.27Å; Y120-F470 WeakPolarHBondContact OH-CD2 3.48Å; F464-F470 WeakPolarHBondContact O-CB 3.28Å; T465-F470 HydrophobicContact CG2-CD1 4.11Å; T465-F470 HydrophobicContact CG2-CE1 3.75Å; T465-F470 HydrophobicContact CG2-CZ 4.31Å; T465-F470 WeakPolarHBondContact O-CD1 3.34Å; S467-F470 WeakPolarHBondContact O-CA 3.06Å; S467-F470 WeakPolarHBondContact O-CB 3.07Å; S467-F470 PolarHBondContact O-N 3.22Å; S467-F470 WeakPolarHBondContact OG-CB 3.09Å; R468-F470 VanDerWaalsContact C-N 3.32Å; R468-F470 PolarHBondContact O-N 3.06Å; F470-V473 PolarHBondContact O-N 2.86Å; F470-L474 PolarHBondContact O-N 3.08Å
471	L	69.1	Low	67.4	Low	14 Å²	14	68.9 Å²	68.9	7%	0.073	34%	0.34	C	S	.	.	H	α-helix	trans	-65.8	-38	179.1	-63.7	175.9	0	0	0	112.1	T465 S467 R468 V473 L474 F475 L486 L489	T465-L471 WeakPolarHBondContact O-CD2 3.37Å; T465-L471 WeakPolarHBondContact O-CG 3.11Å; S467-L471 PolarHBondContact O-N 2.69Å; R468-L471 PolarHBondContact O-N 3.04Å; L471-V473 VanDerWaalsContact C-N 3.27Å; L471-V473 PolarHBondContact O-N 3.07Å; L471-L474 PolarHBondContact O-N 3.23Å; L471-F475 HydrophobicContact CB-CD2 4.24Å; L471-F475 HydrophobicContact CD2-CD2 4.49Å; L471-F475 HydrophobicContact CD2-CE2 4.02Å; L471-F475 WeakPolarHBondContact O-CB 3.38Å; L471-F475 VanDerWaalsContact O-CD2 3.31Å; L471-F475 WeakPolarHBondContact O-CD2 3.38Å; L471-F475 PolarHBondContact O-N 2.97Å; L471-L486 HydrophobicContact CB-CD1 3.27Å; L471-L486 HydrophobicContact CD1-CD1 4.14Å; L471-L486 HydrophobicContact CG-CD1 4.34Å; L471-L489 HydrophobicContact CD1-CD2 4.4Å
472	E	65.7	Low	65.7	Low	47 Å²	47	68 Å²	68	22%	0.22	34%	0.338	C	S	.	.	H	α-helix	trans	-65.1	-28.9	174.1	-76.8	-178.9	-173.5	0	0	113	R468 L486	R468-E472 HydrophobicContact CG-CG 4.17Å; R468-E472 VanDerWaalsContact CG-OE1 3.31Å; R468-E472 WeakPolarHBondContact CG-OE1 3.35Å; R468-E472 IonicContact CZ-OE1 3.69Å; R468-E472 IonicContact NE-OE1 2.79Å; R468-E472 PolarHBondContact NE-OE1 2.69Å; R468-E472 IonicContact NH2-OE1 3.76Å; R468-E472 WeakPolarHBondContact O-CB 3.49Å; R468-E472 VanDerWaalsContact O-CG 3.29Å; R468-E472 WeakPolarHBondContact O-CG 3.05Å; R468-E472 PolarHBondContact O-N 3.34Å; E472-L486 HydrophobicContact CG-CD2 3.48Å; E472-L486 VanDerWaalsContact CG-CD2 3.48Å
473	V	66.6	Low	63.8	Low	35 Å²	35	73.2 Å²	73.2	21%	0.212	35%	0.352	C	S	.	.	H	α-helix	trans	-80.5	-31.4	175.5	172.1	0	0	0	0	111.4	N113 L116 P469 F470 L471	N113-V473 HydrophobicContact CB-CG1 4.37Å; N113-V473 VanDerWaalsContact ND2-CG1 3.31Å; N113-V473 WeakPolarHBondContact ND2-CG1 3.13Å; N113-V473 PolarHBondContact ND2-O 3.27Å; L116-V473 HydrophobicContact CD2-CB 3.9Å; L116-V473 HydrophobicContact CD2-CG1 3.69Å; L116-V473 HydrophobicContact CG-CB 4.39Å; L116-V473 HydrophobicContact CG-CG1 3.62Å; P469-V473 WeakPolarHBondContact O-CB 3.42Å; P469-V473 WeakPolarHBondContact O-CG2 3.48Å; P469-V473 PolarHBondContact O-N 3.5Å; P469-V473 VanDerWaalsContact O-N 3.14Å; F470-V473 PolarHBondContact O-N 2.86Å; L471-V473 VanDerWaalsContact C-N 3.27Å; L471-V473 PolarHBondContact O-N 3.07Å
474	L	66.2	Low	62	Low	88 Å²	88	78.7 Å²	78.7	46%	0.461	38%	0.38	S	S	.	.	H	α-helix	trans	-78.3	-48.5	177.7	-166	73.5	0	0	0	111.8	F470 L471 K476	F470-L474 PolarHBondContact O-N 3.08Å; L471-L474 PolarHBondContact O-N 3.23Å; L474-K476 PolarHBondContact O-N 3.45Å
475	F	64.2	Low	60.7	Low	84 Å²	84	85 Å²	85	37%	0.368	41%	0.407	S	S	.	.	S	Bend	trans	-88.5	92.6	172.5	-61.3	-67.9	0	0	0	108.1	L471 R477 L486	L471-F475 HydrophobicContact CB-CD2 4.24Å; L471-F475 HydrophobicContact CD2-CD2 4.49Å; L471-F475 HydrophobicContact CD2-CE2 4.02Å; L471-F475 WeakPolarHBondContact O-CB 3.38Å; L471-F475 VanDerWaalsContact O-CD2 3.31Å; L471-F475 WeakPolarHBondContact O-CD2 3.38Å; L471-F475 PolarHBondContact O-N 2.97Å; F475-R477 PolarHBondContact O-N 3.26Å; F475-L486 HydrophobicContact CD2-CD1 4.28Å
476	K	58	Low	59.5	Low	154 Å²	154	84.2 Å²	84.2	67%	0.67	40%	0.402	S	S	*	.			trans	-35.2	129.5	-178.6	-72.1	178.7	179.5	174.4	0	111.9	L474 D478 D479	L474-K476 PolarHBondContact O-N 3.45Å; K476-D478 PolarHBondContact O-N 3.08Å; K476-D479 PolarHBondContact O-N 2.9Å
477	R	53.5	Low	58.6	Low	148 Å²	148	83.3 Å²	83.3	56%	0.558	40%	0.401	S	S	*	.	T	Hydrogen-bonded Turn	trans	-50.9	-18	-178.9	-142.4	177.9	-170.1	142.9	8.2	114.9	F475	F475-R477 PolarHBondContact O-N 3.26Å
478	D	51.4	Low	57.7	Low	147 Å²	147	86.8 Å²	86.8	79%	0.786	42%	0.418	S	S	*	.	T	Hydrogen-bonded Turn	trans	-102.2	-2.6	-173	-55.4	-39.7	0	0	0	114.2	K476 P480	K476-D478 PolarHBondContact O-N 3.08Å; D478-P480 WeakPolarHBondContact O-CD 3.41Å
479	D	49.4	Very low	57.2	Low	93 Å²	93	83 Å²	83	50%	0.497	41%	0.409	S	S	.	.			trans	-87.8	109.6	173.6	-82.7	-37.2	0	0	0	110.4	K476 L481 G482 R483	K476-D479 PolarHBondContact O-N 2.9Å; D479-L481 PolarHBondContact O-N 2.71Å; D479-G482 VanDerWaalsContact O-CA 3.31Å; D479-G482 WeakPolarHBondContact O-CA 3.48Å; D479-G482 PolarHBondContact O-N 2.78Å; D479-R483 PolarHBondContact O-N 3.06Å
480	P	48.7	Very low	56.6	Low	90 Å²	90	84.5 Å²	84.5	58%	0.584	42%	0.423	S	S	*	.	H	α-helix	trans	-61.6	-32.8	178.4	23.5	-32.5	0	0	0	111.9	D478 G482 R483 L484	D478-P480 WeakPolarHBondContact O-CD 3.41Å; P480-G482 VanDerWaalsContact C-N 3.33Å; P480-R483 PolarHBondContact O-N 2.6Å; P480-L484 WeakPolarHBondContact O-CD1 3.1Å; P480-L484 PolarHBondContact O-N 3.36Å
481	L	49.4	Very low	55.7	Low	130 Å²	130	92.2 Å²	92.2	68%	0.681	46%	0.462	S	S	*	.	H	α-helix	trans	-67.4	-32.7	169.9	-97.6	79.2	0	0	0	112.6	D479 K485	D479-L481 PolarHBondContact O-N 2.71Å; L481-K485 WeakPolarHBondContact O-CB 3.47Å; L481-K485 WeakPolarHBondContact O-CG 3.09Å; L481-K485 PolarHBondContact O-N 2.84Å
482	G	53.4	Low	54.8	Low	10 Å²	10	98.4 Å²	98.4	10%	0.103	49%	0.49	C	S	.	.	H	α-helix	trans	-65.4	-41.7	176	0	0	0	0	0	111.5	D479 P480 K485 L486	D479-G482 VanDerWaalsContact O-CA 3.31Å; D479-G482 WeakPolarHBondContact O-CA 3.48Å; D479-G482 PolarHBondContact O-N 2.78Å; P480-G482 VanDerWaalsContact C-N 3.33Å; G482-K485 PolarHBondContact O-N 3.15Å; G482-L486 WeakPolarHBondContact O-CB 3.13Å; G482-L486 PolarHBondContact O-N 3.16Å
483	R	48.7	Very low	53.9	Low	160 Å²	160	99.3 Å²	99.3	60%	0.604	50%	0.496	S	S	*	.	H	α-helix	trans	-63.2	-45.8	173.9	-102.5	-179.7	159	173.6	-6.7	113.2	D479 P480 K485 L486 D487	D479-R483 PolarHBondContact O-N 3.06Å; P480-R483 PolarHBondContact O-N 2.6Å; R483-K485 PolarHBondContact O-N 2.88Å; R483-L486 WeakPolarHBondContact O-CB 3.33Å; R483-L486 PolarHBondContact O-N 3.1Å; R483-D487 WeakPolarHBondContact O-CB 3.32Å; R483-D487 PolarHBondContact O-N 3Å
484	L	47.7	Very low	52.5	Low	128 Å²	128	103.5 Å²	103.5	67%	0.67	52%	0.524	S	S	*	.	H	α-helix	trans	-64	-40	176.2	-93.7	109.4	0	0	0	112.4	P480 N488	P480-L484 WeakPolarHBondContact O-CD1 3.1Å; P480-L484 PolarHBondContact O-N 3.36Å; L484-N488 WeakPolarHBondContact O-CB 3.46Å; L484-N488 PolarHBondContact O-N 2.89Å
485	K	56.3	Low	51.5	Low	133 Å²	133	105.2 Å²	105.2	58%	0.578	53%	0.533	S	S	*	.	H	α-helix	trans	-66.2	-38	174.4	-76.9	-176.8	177.8	-177.4	0	112.2	L481 G482 R483 L489	L481-K485 WeakPolarHBondContact O-CB 3.47Å; L481-K485 WeakPolarHBondContact O-CG 3.09Å; L481-K485 PolarHBondContact O-N 2.84Å; G482-K485 PolarHBondContact O-N 3.15Å; R483-K485 PolarHBondContact O-N 2.88Å; K485-L489 WeakPolarHBondContact O-CB 3.21Å; K485-L489 PolarHBondContact O-N 2.95Å
486	L	56.7	Low	49.9	Very low	13 Å²	13	104.6 Å²	104.6	7%	0.068	55%	0.551	C	S	.	*	H	α-helix	trans	-65.7	-45.1	177.6	-170.5	82.9	0	0	0	111.8	L471 E472 F475 G482 R483 L489 A490	L471-L486 HydrophobicContact CB-CD1 3.27Å; L471-L486 HydrophobicContact CD1-CD1 4.14Å; L471-L486 HydrophobicContact CG-CD1 4.34Å; E472-L486 HydrophobicContact CG-CD2 3.48Å; E472-L486 VanDerWaalsContact CG-CD2 3.48Å; F475-L486 HydrophobicContact CD2-CD1 4.28Å; G482-L486 WeakPolarHBondContact O-CB 3.13Å; G482-L486 PolarHBondContact O-N 3.16Å; R483-L486 WeakPolarHBondContact O-CB 3.33Å; R483-L486 PolarHBondContact O-N 3.1Å; L486-L489 PolarHBondContact O-N 3.4Å; L486-A490 WeakPolarHBondContact O-CB 3.24Å; L486-A490 PolarHBondContact O-N 2.9Å
487	D	54.3	Low	48.9	Very low	77 Å²	77	102.2 Å²	102.2	41%	0.412	55%	0.548	S	S	.	.	H	α-helix	trans	-69.3	-35.5	178.7	-72.2	-26.1	0	0	0	111.1	R483 A490 M491	R483-D487 WeakPolarHBondContact O-CB 3.32Å; R483-D487 PolarHBondContact O-N 3Å; D487-A490 PolarHBondContact O-N 2.81Å; D487-M491 WeakPolarHBondContact O-CB 3.33Å; D487-M491 WeakPolarHBondContact O-CG 3.26Å; D487-M491 PolarHBondContact O-N 3.11Å
488	N	55	Low	47.9	Very low	94 Å²	94	105 Å²	105	50%	0.503	57%	0.565	S	S	.	*	H	α-helix	trans	-67.6	-42	172.6	-122.5	-21.3	0	0	0	112.3	L484 M491 Q492	L484-N488 WeakPolarHBondContact O-CB 3.46Å; L484-N488 PolarHBondContact O-N 2.89Å; N488-M491 PolarHBondContact O-N 3.26Å; N488-Q492 WeakPolarHBondContact O-CB 3.5Å; N488-Q492 VanDerWaalsContact O-CG 3.26Å; N488-Q492 WeakPolarHBondContact O-CG 3.36Å; N488-Q492 PolarHBondContact O-N 3.1Å; N488-Q492 VanDerWaalsContact O-N 3.16Å
489	L	53	Low	47.2	Very low	68 Å²	68	102.5 Å²	102.5	36%	0.356	55%	0.549	S	S	.	.	H	α-helix	trans	-63.6	-43	174.1	-113.3	94.2	0	0	0	111.3	F466 L471 K485 L486 Q492 L493	F466-L489 HydrophobicContact CD1-CD2 4.49Å; F466-L489 HydrophobicContact CE1-CD2 4.49Å; L471-L489 HydrophobicContact CD1-CD2 4.4Å; K485-L489 WeakPolarHBondContact O-CB 3.21Å; K485-L489 PolarHBondContact O-N 2.95Å; L486-L489 PolarHBondContact O-N 3.4Å; L489-Q492 PolarHBondContact O-N 2.91Å; L489-L493 VanDerWaalsContact O-CD1 3.29Å; L489-L493 WeakPolarHBondContact O-CD1 3.45Å; L489-L493 WeakPolarHBondContact O-CG 3.28Å; L489-L493 PolarHBondContact O-N 2.94Å
490	A	55.1	Low	46.1	Very low	55 Å²	55	103.4 Å²	103.4	46%	0.455	56%	0.562	S	S	.	*	H	α-helix	trans	-67.9	-33.8	-178.9	0	0	0	0	0	112.6	L486 D487	L486-A490 WeakPolarHBondContact O-CB 3.24Å; L486-A490 PolarHBondContact O-N 2.9Å; D487-A490 PolarHBondContact O-N 2.81Å
491	M	47.9	Very low	45.3	Very low	169 Å²	169	106.9 Å²	106.9	83%	0.833	57%	0.57	S	S	*	*	H	α-helix	trans	-74.5	-27.7	174.7	-82.5	-167.7	172.8	0	0	113.7	D487 N488	D487-M491 WeakPolarHBondContact O-CB 3.33Å; D487-M491 WeakPolarHBondContact O-CG 3.26Å; D487-M491 PolarHBondContact O-N 3.11Å; N488-M491 PolarHBondContact O-N 3.26Å
492	Q	48.9	Very low	44.3	Very low	144 Å²	144	111 Å²	111	67%	0.673	58%	0.577	S	S	*	*	H	α-helix	trans	-90.3	-7.5	-177	-70	178.1	6	0	0	114.1	N488 L489 P494	N488-Q492 WeakPolarHBondContact O-CB 3.5Å; N488-Q492 VanDerWaalsContact O-CG 3.26Å; N488-Q492 WeakPolarHBondContact O-CG 3.36Å; N488-Q492 PolarHBondContact O-N 3.1Å; N488-Q492 VanDerWaalsContact O-N 3.16Å; L489-Q492 PolarHBondContact O-N 2.91Å; Q492-P494 WeakPolarHBondContact O-CD 3.35Å
493	L	46.7	Very low	43.2	Very low	65 Å²	65	114.9 Å²	114.9	34%	0.34	60%	0.602	S	S	.	*			trans	-88.8	116.3	-178.9	-81.8	159.7	0	0	0	111.1	F466 L489 L495	F466-L493 HydrophobicContact CB-CD1 4.45Å; F466-L493 HydrophobicContact CD1-CD1 4.31Å; L489-L493 VanDerWaalsContact O-CD1 3.29Å; L489-L493 WeakPolarHBondContact O-CD1 3.45Å; L489-L493 WeakPolarHBondContact O-CG 3.28Å; L489-L493 PolarHBondContact O-N 2.94Å; L493-L495 PolarHBondContact O-N 2.93Å
494	P	38.7	Very low	42.2	Very low	124 Å²	124	113.7 Å²	113.7	81%	0.805	61%	0.606	S	S	*	*			trans	-77.6	45	178.5	33.4	-35.5	0	0	0	112.5	Q492	Q492-P494 WeakPolarHBondContact O-CD 3.35Å
495	L	44.1	Very low	41.4	Very low	123 Å²	123	112.3 Å²	112.3	64%	0.644	61%	0.605	S	S	*	*	S	Bend	trans	-129.3	72.2	179.1	-71.3	170.6	0	0	0	110.8	L493 V497	L493-L495 PolarHBondContact O-N 2.93Å; L495-V497 PolarHBondContact O-N 3.15Å
496	G	30.5	Very low	40.1	Very low	72 Å²	72	114.5 Å²	114.5	74%	0.742	62%	0.62	S	S	*	*			trans	46.5	68.9	143.7	0	0	0	0	0	117.8
497	V	38.3	Very low	38.7	Very low	103 Å²	103	118.9 Å²	118.9	62%	0.624	65%	0.652	S	S	*	*			trans	-126.6	60.4	152.1	-167	0	0	0	0	108.7	L495 H499	L495-V497 PolarHBondContact O-N 3.15Å; V497-H499 VanDerWaalsContact C-N 3.31Å; V497-H499 PolarHBondContact O-N 3.27Å
498	F	31.1	Very low	37.6	Very low	206 Å²	206	120.5 Å²	120.5	90%	0.904	67%	0.669	S	S	*	*			trans	-80.9	90.4	153.4	-81.2	-82.1	0	0	0	107.1	S500	F498-S500 PolarHBondContact O-N 2.69Å
499	H	37.1	Very low	36.5	Very low	96 Å²	96	123.8 Å²	123.8	44%	0.444	69%	0.686	S	S	.	*			trans	-61.9	120.4	146.4	-96.6	65.4	0	0	0	105.5	K414 R418 V497 H501	K414-H499 PolarHBondContact NZ-NE2 2.85Å; R418-H499 PolarHBondContact NH2-CE1 3.38Å; V497-H499 VanDerWaalsContact C-N 3.31Å; V497-H499 PolarHBondContact O-N 3.27Å; H499-H501 PolarHBondContact O-N 3.36Å
500	S	26.8	Very low	35.6	Very low	112 Å²	112	126.4 Å²	126.4	78%	0.783	71%	0.705	S	S	*	*			trans	-57.9	91.3	160.9	179.2	0	0	0	0	107	F498 R502	F498-S500 PolarHBondContact O-N 2.69Å; S500-R502 PolarHBondContact O-N 3.14Å
501	H	32.4	Very low	34.5	Very low	163 Å²	163	127.3 Å²	127.3	76%	0.755	72%	0.719	S	S	*	*			trans	-65.1	93.1	153.2	-90.1	-80.8	0	0	0	104.5	H499 S503	H499-H501 PolarHBondContact O-N 3.36Å; H501-S503 PolarHBondContact O-N 3.29Å
502	R	27.3	Very low	33.8	Very low	215 Å²	215	124.1 Å²	124.1	81%	0.811	71%	0.714	S	S	*	*			trans	-64.3	77.3	150.7	-152.8	-178.9	-165.3	176.8	4.2	105.9	S500 I504	S500-R502 PolarHBondContact O-N 3.14Å; R502-I504 VanDerWaalsContact C-N 3.26Å; R502-I504 HydrophobicContact CG-CG1 4.27Å; R502-I504 PolarHBondContact O-N 3.4Å
503	S	30.8	Very low	32.9	Very low	92 Å²	92	122.9 Å²	122.9	64%	0.643	72%	0.721	S	S	*	*			trans	-63.6	98.1	157.1	42.3	0	0	0	0	104.7	H501 P505	H501-S503 PolarHBondContact O-N 3.29Å; S503-P505 WeakPolarHBondContact O-CD 3.4Å
504	I	28.2	Very low	32.3	Very low	135 Å²	135	125.1 Å²	125.1	69%	0.692	74%	0.737	S	S	*	*			trans	-88.1	97.1	150.5	-61.1	175.3	0	0	0	103.6	R502 M506	R502-I504 VanDerWaalsContact C-N 3.26Å; R502-I504 HydrophobicContact CG-CG1 4.27Å; R502-I504 PolarHBondContact O-N 3.4Å; I504-M506 PolarHBondContact O-N 2.89Å
505	P	29.5	Very low	32.2	Very low	100 Å²	100	126.9 Å²	126.9	65%	0.649	74%	0.738	S	S	*	*			trans	-72	125.4	166.6	30.1	-30	0	0	0	108.2	S503	S503-P505 WeakPolarHBondContact O-CD 3.4Å
506	M	29.5	Very low	31.6	Very low	178 Å²	178	126.1 Å²	126.1	88%	0.877	74%	0.743	S	S	*	*			trans	59.1	116.2	135.8	-80.3	-178.6	157	0	0	119.8	I504	I504-M506 PolarHBondContact O-N 2.89Å
507	S	27.8	Very low	31.8	Very low	106 Å²	106	128 Å²	128	74%	0.741	74%	0.742	S	S	*	*				55	95.8	118.7	166.7	0	0	0	0	117.1
508	S	31.1	Very low	31.6	Very low	111 Å²	111	130.6 Å²	130.6	78%	0.776	75%	0.752	S	S	*	*			trans	-112.8	79	141.8	62.6	0	0	0	0	108.8	V510	S508-V510 PolarHBondContact O-N 2.82Å
509	N	31.1	Very low	32	Very low	162 Å²	162	127.9 Å²	127.9	87%	0.866	75%	0.745	S	S	*	*			trans	-73.3	82.2	158.4	-119.7	-1.7	0	0	0	107	G511	N509-G511 PolarHBondContact O-N 3.07Å
510	V	35.1	Very low	32.3	Very low	124 Å²	124	136.6 Å²	136.6	75%	0.752	78%	0.782	S	S	*	*			trans	-86.7	90.5	162.9	179.9	0	0	0	0	106.3	S508 S512	S508-V510 PolarHBondContact O-N 2.82Å; V510-S512 PolarHBondContact O-N 3.41Å
511	G	31.2	Very low	32.6	Very low	73 Å²	73	137.8 Å²	137.8	75%	0.753	78%	0.782	S	S	*	*			trans	-66.9	121.6	159.2	0	0	0	0	0	108.8	N509	N509-G511 PolarHBondContact O-N 3.07Å
512	S	33.4	Very low	32.6	Very low	103 Å²	103	136.5 Å²	136.5	72%	0.72	78%	0.783	S	S	*	*			trans	-140.2	100.7	144.3	62.9	0	0	0	0	107.9	V510 V514	V510-S512 PolarHBondContact O-N 3.41Å; S512-V514 PolarHBondContact O-N 3.04Å
513	S	29.7	Very low	32.9	Very low	117 Å²	117	132.1 Å²	132.1	82%	0.818	78%	0.782	S	S	*	*			trans	-72.2	97.4	166.8	53.3	0	0	0	0	108.7
514	V	34.5	Very low	33	Very low	113 Å²	113	134.5 Å²	134.5	69%	0.685	79%	0.79	S	S	*	*			trans	-148.2	100	163.4	-173.5	0	0	0	0	109.6	S512	S512-V514 PolarHBondContact O-N 3.04Å
515	I	36.3	Very low	33.3	Very low	160 Å²	160	134.4 Å²	134.4	82%	0.821	80%	0.796	S	S	*	*			trans	68.8	110.4	137	-53.8	171.6	0	0	0	117.8
516	S	31.2	Very low	33.6	Very low	108 Å²	108	136.7 Å²	136.7	76%	0.755	81%	0.806	S	S	*	*			trans	-57	-171.6	160.8	-49.5	0	0	0	0	113.6
517	P	34.9	Very low	33.9	Very low	111 Å²	111	133.8 Å²	133.8	72%	0.721	80%	0.8	S	S	*	*				-126.6	151.6	-79.1	36.3	-20.1	0	0	0	110.8
518	L	35.3	Very low	34.3	Very low	158 Å²	158	135.9 Å²	135.9	83%	0.827	81%	0.805	S	S	*	*			trans	-167.4	113	159.4	-109	130.4	0	0	0	113.8
519	I	38.7	Very low	34.6	Very low	148 Å²	148	138 Å²	138	76%	0.759	81%	0.807	S	S	*	*				48.7	103.9	129.9	-48.4	-176	0	0	0	117.7
520	K	43.4	Very low	34.9	Very low	279 Å²	279	135.8 Å²	135.8	100%	1.213	80%	0.802	S	S	*	*				-161.5	0	104.5	-122.6	179.8	-174.9	179.2	0	110.7

Retrieved 520 of 520 residues in 656.7 ms (Link to these results)

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