A0A3Q0KRR5_SCHMA Loading...

BEACH domain-containing protein

AlphaFold DB , UniProt , Accession A0A3Q0KRR5, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 713 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	27.7	Very low	32.4	Very low	211 Å²	211	117.7 Å²	117.7	100%	1.039	60%	0.599	S	S	*	*				0	122.8	0	-74.6	-174.2	159.5	0	0	108.3	N3	M1-N3 PolarHBondContact O-N 3.39Å
2	P	26.6	Very low	32.9	Very low	131 Å²	131	112 Å²	112	85%	0.851	57%	0.568	S	S	*	*			trans	-61	131.1	163.8	-10.8	26.7	0	0	0	107.7	L4	P2-L4 PolarHBondContact O-N 2.79Å
3	N	29.7	Very low	33.3	Very low	119 Å²	119	108.5 Å²	108.5	64%	0.636	55%	0.545	S	S	*	.			trans	-52.8	126.3	-168.6	-73.2	-37.3	0	0	0	113.1	M1 Y5 D6	M1-N3 PolarHBondContact O-N 3.39Å; N3-Y5 HydrophobicContact CB-CD2 4.32Å; N3-Y5 PolarHBondContact O-N 3.38Å; N3-D6 PolarHBondContact O-N 2.97Å
4	L	28.7	Very low	33.6	Very low	120 Å²	120	104.9 Å²	104.9	63%	0.628	53%	0.527	S	S	*	.	G	3₁₀ helix	trans	-57.5	-8.5	166.8	-98.5	117.2	0	0	0	113.7	P2 D6	P2-L4 PolarHBondContact O-N 2.79Å; L4-D6 PolarHBondContact O-N 3.27Å
5	Y	27.1	Very low	34.4	Very low	214 Å²	214	104 Å²	104	84%	0.839	52%	0.516	S	S	*	.	G	3₁₀ helix	trans	-70.7	-10.3	175.6	-72.8	-79.7	0	0	0	114.7	N3	N3-Y5 HydrophobicContact CB-CD2 4.32Å; N3-Y5 PolarHBondContact O-N 3.38Å
6	D	28.7	Very low	34.9	Very low	133 Å²	133	105.3 Å²	105.3	71%	0.711	51%	0.513	S	S	*	.	G	3₁₀ helix	trans	-90	4.1	177.4	-76	-31.4	0	0	0	114.3	N3 L4 V8	N3-D6 PolarHBondContact O-N 2.97Å; L4-D6 PolarHBondContact O-N 3.27Å; D6-V8 PolarHBondContact O-N 3.3Å; D6-V8 VanDerWaalsContact O-N 3.12Å
7	R	31.1	Very low	35	Very low	170 Å²	170	101.2 Å²	101.2	64%	0.642	49%	0.494	S	S	*	.	S	Bend	trans	-80.5	93.5	167.7	-71.3	-172.3	179.5	-169.2	-0.5	109.3	S9	R7-S9 PolarHBondContact O-N 3.49Å
8	V	36.7	Very low	35.3	Very low	50 Å²	50	102.8 Å²	102.8	30%	0.303	50%	0.498	S	S	.	.			trans	-37.2	118.3	169.1	175.8	0	0	0	0	109.7	D6 E12	D6-V8 PolarHBondContact O-N 3.3Å; D6-V8 VanDerWaalsContact O-N 3.12Å; V8-E12 WeakPolarHBondContact CA-OE2 3.43Å; V8-E12 HydrophobicContact CG1-CB 3.59Å; V8-E12 HydrophobicContact CG1-CG 3.7Å
9	S	37.9	Very low	35.7	Very low	48 Å²	48	100.6 Å²	100.6	34%	0.336	49%	0.488	S	S	.	.			trans	-64.3	154.7	178.6	64.4	0	0	0	0	110.5	R7 S11 E12 Y13	R7-S9 PolarHBondContact O-N 3.49Å; S9-S11 PolarHBondContact O-N 2.96Å; S9-S11 PolarHBondContact OG-OG 3.33Å; S9-E12 PolarHBondContact N-OE2 2.76Å; S9-E12 CarbonylContact O-C 3.6Å; S9-E12 WeakPolarHBondContact O-CA 3.08Å; S9-E12 VanDerWaalsContact O-CB 3.29Å; S9-E12 WeakPolarHBondContact O-CB 3.09Å; S9-E12 PolarHBondContact O-N 2.77Å; S9-E12 WeakPolarHBondContact OG-CB 3.16Å; S9-E12 PolarHBondContact OG-N 2.94Å; S9-Y13 PolarHBondContact O-N 2.94Å
10	F	38.6	Very low	35.8	Very low	34 Å²	34	101.7 Å²	101.7	15%	0.149	49%	0.49	C	S	.	.	H	α-helix	trans	-59.8	-31.5	-179.9	-176.1	-103.1	0	0	0	113	E12 Y13 I14 L384 E388	F10-E12 VanDerWaalsContact C-N 3.35Å; F10-Y13 HydrophobicContact CD2-CD1 4.32Å; F10-Y13 HydrophobicContact CE2-CD1 4.47Å; F10-Y13 CarbonylContact O-C 3.32Å; F10-Y13 WeakPolarHBondContact O-CB 3.4Å; F10-Y13 PolarHBondContact O-N 2.98Å; F10-I14 HydrophobicContact CD1-CD1 3.91Å; F10-I14 HydrophobicContact CD1-CG1 4.32Å; F10-I14 HydrophobicContact CE1-CD1 3.5Å; F10-I14 VanDerWaalsContact CE1-CD1 3.5Å; F10-I14 HydrophobicContact CE1-CG1 4.14Å; F10-I14 HydrophobicContact CZ-CD1 4.15Å; F10-I14 HydrophobicContact CZ-CG1 4.5Å; F10-I14 WeakPolarHBondContact O-CG1 3.49Å; F10-I14 PolarHBondContact O-N 3.2Å; F10-L384 HydrophobicContact CE1-CD2 4.35Å; F10-L384 HydrophobicContact CE2-CD2 3.29Å; F10-L384 HydrophobicContact CE2-CG 4.48Å; F10-L384 HydrophobicContact CZ-CB 3.78Å; F10-L384 HydrophobicContact CZ-CD1 4.35Å; F10-L384 HydrophobicContact CZ-CD2 3.16Å; F10-L384 HydrophobicContact CZ-CG 3.91Å; F10-E388 HydrophobicContact CD1-CG 4.01Å; F10-E388 WeakPolarHBondContact CD1-OE1 3.2Å; F10-E388 HydrophobicContact CE1-CG 3.57Å; F10-E388 HydrophobicContact CZ-CG 4.32Å
11	S	43.4	Very low	35.9	Very low	65 Å²	65	101.7 Å²	101.7	46%	0.455	49%	0.493	S	S	.	.	H	α-helix	trans	-64.4	-38.6	169.7	49.5	0	0	0	0	112.1	S9 Y13 I14 Y15	S9-S11 PolarHBondContact O-N 2.96Å; S9-S11 PolarHBondContact OG-OG 3.33Å; S11-Y13 VanDerWaalsContact C-N 3.32Å; S11-I14 PolarHBondContact O-N 2.86Å; S11-Y15 WeakPolarHBondContact O-CB 3.26Å; S11-Y15 PolarHBondContact O-N 2.8Å
12	E	39	Very low	36.6	Very low	49 Å²	49	94.4 Å²	94.4	23%	0.229	46%	0.46	C	S	.	.	H	α-helix	trans	-71.3	-26.7	173.3	-162.2	-172.4	167.3	0	0	111.9	V8 S9 F10 R16	V8-E12 WeakPolarHBondContact CA-OE2 3.43Å; V8-E12 HydrophobicContact CG1-CB 3.59Å; V8-E12 HydrophobicContact CG1-CG 3.7Å; S9-E12 PolarHBondContact N-OE2 2.76Å; S9-E12 CarbonylContact O-C 3.6Å; S9-E12 WeakPolarHBondContact O-CA 3.08Å; S9-E12 VanDerWaalsContact O-CB 3.29Å; S9-E12 WeakPolarHBondContact O-CB 3.09Å; S9-E12 PolarHBondContact O-N 2.77Å; S9-E12 WeakPolarHBondContact OG-CB 3.16Å; S9-E12 PolarHBondContact OG-N 2.94Å; F10-E12 VanDerWaalsContact C-N 3.35Å; E12-R16 VanDerWaalsContact O-CB 3.23Å; E12-R16 WeakPolarHBondContact O-CB 3.47Å; E12-R16 WeakPolarHBondContact O-CG 3.41Å; E12-R16 PolarHBondContact O-N 2.86Å
13	Y	38.4	Very low	37	Very low	67 Å²	67	91.7 Å²	91.7	26%	0.263	44%	0.437	S	S	.	.	H	α-helix	trans	-73.7	-43.7	169.9	-179.7	-110.7	0	0	0	112.3	S9 F10 S11 Y15 R16 I17 Y380 I435	S9-Y13 PolarHBondContact O-N 2.94Å; F10-Y13 HydrophobicContact CD2-CD1 4.32Å; F10-Y13 HydrophobicContact CE2-CD1 4.47Å; F10-Y13 CarbonylContact O-C 3.32Å; F10-Y13 WeakPolarHBondContact O-CB 3.4Å; F10-Y13 PolarHBondContact O-N 2.98Å; S11-Y13 VanDerWaalsContact C-N 3.32Å; Y13-Y15 VanDerWaalsContact C-N 3.34Å; Y13-R16 CarbonylContact O-C 3.55Å; Y13-R16 WeakPolarHBondContact O-CB 3.28Å; Y13-R16 PolarHBondContact O-N 3.18Å; Y13-I17 HydrophobicContact CD1-CD1 3.83Å; Y13-I17 HydrophobicContact CD2-CD1 4.37Å; Y13-I17 HydrophobicContact CE1-CD1 3.28Å; Y13-I17 HydrophobicContact CE1-CG1 4.33Å; Y13-I17 HydrophobicContact CE2-CD1 3.86Å; Y13-I17 HydrophobicContact CE2-CG1 4.21Å; Y13-I17 HydrophobicContact CG-CD1 4.37Å; Y13-I17 WeakPolarHBondContact O-CG1 3.22Å; Y13-I17 PolarHBondContact O-N 3.01Å; Y13-Y380 WeakPolarHBondContact CE1-OH 3.34Å; Y13-I435 HydrophobicContact CE1-CD1 4.28Å
14	I	37.6	Very low	37.2	Very low	58 Å²	58	91 Å²	91	30%	0.297	43%	0.431	S	S	.	.	H	α-helix	trans	-63.4	-42.6	172.8	-70.7	-177.7	0	0	0	110.1	F10 S11 I17 K18 L384	F10-I14 HydrophobicContact CD1-CD1 3.91Å; F10-I14 HydrophobicContact CD1-CG1 4.32Å; F10-I14 HydrophobicContact CE1-CD1 3.5Å; F10-I14 VanDerWaalsContact CE1-CD1 3.5Å; F10-I14 HydrophobicContact CE1-CG1 4.14Å; F10-I14 HydrophobicContact CZ-CD1 4.15Å; F10-I14 HydrophobicContact CZ-CG1 4.5Å; F10-I14 WeakPolarHBondContact O-CG1 3.49Å; F10-I14 PolarHBondContact O-N 3.2Å; S11-I14 PolarHBondContact O-N 2.86Å; I14-I17 PolarHBondContact O-N 2.88Å; I14-K18 HydrophobicContact CG2-CD 4.38Å; I14-K18 HydrophobicContact CG2-CG 4.48Å; I14-K18 WeakPolarHBondContact O-CB 3.43Å; I14-K18 PolarHBondContact O-N 3.38Å; I14-L384 HydrophobicContact CD1-CD1 4.33Å; I14-L384 HydrophobicContact CG1-CD1 4.47Å
15	Y	44.9	Very low	37.5	Very low	91 Å²	91	89.3 Å²	89.3	36%	0.357	42%	0.422	S	S	.	.	H	α-helix	trans	-64.2	-42.1	174.5	-163.8	-97.1	0	0	0	110.6	S11 Y13 I17 K18 L19 L91 Y98	S11-Y15 WeakPolarHBondContact O-CB 3.26Å; S11-Y15 PolarHBondContact O-N 2.8Å; Y13-Y15 VanDerWaalsContact C-N 3.34Å; Y15-I17 PolarHBondContact O-N 3.18Å; Y15-K18 PolarHBondContact O-N 3.2Å; Y15-L19 HydrophobicContact CD1-CD1 4.45Å; Y15-L19 HydrophobicContact CE1-CD1 3.68Å; Y15-L19 WeakPolarHBondContact O-CB 3.08Å; Y15-L19 PolarHBondContact O-N 3.4Å; Y15-L91 WeakPolarHBondContact OH-CD1 3.05Å; Y15-Y98 VanDerWaalsContact CD1-OH 3.27Å; Y15-Y98 WeakPolarHBondContact CD1-OH 3.26Å; Y15-Y98 AromaticContact CE1-CZ 3.91Å; Y15-Y98 WeakPolarHBondContact CE1-OH 3.31Å
16	R	41.8	Very low	37.7	Very low	125 Å²	125	86.5 Å²	86.5	47%	0.472	41%	0.414	S	S	.	.	H	α-helix	trans	-60	-40.5	170.8	-90.4	-178.1	170	-162.5	-5.1	112.8	E12 Y13 K20	E12-R16 VanDerWaalsContact O-CB 3.23Å; E12-R16 WeakPolarHBondContact O-CB 3.47Å; E12-R16 WeakPolarHBondContact O-CG 3.41Å; E12-R16 PolarHBondContact O-N 2.86Å; Y13-R16 CarbonylContact O-C 3.55Å; Y13-R16 WeakPolarHBondContact O-CB 3.28Å; Y13-R16 PolarHBondContact O-N 3.18Å; R16-K20 WeakPolarHBondContact O-CA 3.38Å; R16-K20 WeakPolarHBondContact O-CB 3.46Å; R16-K20 PolarHBondContact O-N 2.74Å
17	I	37.3	Very low	38.4	Very low	36 Å²	36	83.7 Å²	83.7	19%	0.185	41%	0.405	C	S	.	.	H	α-helix	trans	-71.5	-44.6	179.3	-75.5	177.1	0	0	0	110.5	Y13 I14 Y15 L19 K20 N21 Y380	Y13-I17 HydrophobicContact CD1-CD1 3.83Å; Y13-I17 HydrophobicContact CD2-CD1 4.37Å; Y13-I17 HydrophobicContact CE1-CD1 3.28Å; Y13-I17 HydrophobicContact CE1-CG1 4.33Å; Y13-I17 HydrophobicContact CE2-CD1 3.86Å; Y13-I17 HydrophobicContact CE2-CG1 4.21Å; Y13-I17 HydrophobicContact CG-CD1 4.37Å; Y13-I17 WeakPolarHBondContact O-CG1 3.22Å; Y13-I17 PolarHBondContact O-N 3.01Å; I14-I17 PolarHBondContact O-N 2.88Å; Y15-I17 PolarHBondContact O-N 3.18Å; I17-L19 VanDerWaalsContact C-N 3.33Å; I17-L19 PolarHBondContact O-N 3.46Å; I17-K20 PolarHBondContact O-N 2.79Å; I17-N21 WeakPolarHBondContact CG2-ND2 3.43Å; I17-N21 WeakPolarHBondContact O-CA 3.37Å; I17-N21 WeakPolarHBondContact O-CB 3.18Å; I17-N21 PolarHBondContact O-N 2.99Å; I17-Y380 HydrophobicContact CD1-CE1 4.35Å; I17-Y380 WeakPolarHBondContact CD1-OH 3.29Å
18	K	41.1	Very low	38.8	Very low	130 Å²	130	80.9 Å²	80.9	57%	0.565	40%	0.395	S	S	*	.	H	α-helix	trans	-61.9	-45.4	175.5	-74.5	-170.5	176	-173.9	0	110.2	I14 Y15 V22	I14-K18 HydrophobicContact CG2-CD 4.38Å; I14-K18 HydrophobicContact CG2-CG 4.48Å; I14-K18 WeakPolarHBondContact O-CB 3.43Å; I14-K18 PolarHBondContact O-N 3.38Å; Y15-K18 PolarHBondContact O-N 3.2Å; K18-V22 VanDerWaalsContact O-CB 3.25Å; K18-V22 WeakPolarHBondContact O-CB 3.5Å; K18-V22 WeakPolarHBondContact O-CG2 3.39Å; K18-V22 PolarHBondContact O-N 3.49Å
19	L	42.9	Very low	38.6	Very low	60 Å²	60	83.7 Å²	83.7	31%	0.314	41%	0.405	S	S	.	.	H	α-helix	trans	-65.5	-43.1	176.4	-150.7	100.3	0	0	0	111.8	Y15 I17 V22 I23 Y98	Y15-L19 HydrophobicContact CD1-CD1 4.45Å; Y15-L19 HydrophobicContact CE1-CD1 3.68Å; Y15-L19 WeakPolarHBondContact O-CB 3.08Å; Y15-L19 PolarHBondContact O-N 3.4Å; I17-L19 VanDerWaalsContact C-N 3.33Å; I17-L19 PolarHBondContact O-N 3.46Å; L19-V22 PolarHBondContact O-N 2.88Å; L19-I23 HydrophobicContact CD2-CD1 3.62Å; L19-I23 HydrophobicContact CG-CD1 3.87Å; L19-I23 VanDerWaalsContact O-CB 3.3Å; L19-I23 WeakPolarHBondContact O-CB 3.43Å; L19-I23 VanDerWaalsContact O-CD1 3.28Å; L19-I23 WeakPolarHBondContact O-CD1 3.34Å; L19-I23 WeakPolarHBondContact O-CG1 3.31Å; L19-I23 PolarHBondContact O-N 3.38Å; L19-Y98 HydrophobicContact CD2-CE1 4.43Å
20	K	36.8	Very low	38.5	Very low	123 Å²	123	88.9 Å²	88.9	54%	0.535	42%	0.424	S	S	.	.	H	α-helix	trans	-73.8	-34.1	-178.4	-160.4	-173.7	-161.8	-167	0	111.7	R16 I17 I23 H24	R16-K20 WeakPolarHBondContact O-CA 3.38Å; R16-K20 WeakPolarHBondContact O-CB 3.46Å; R16-K20 PolarHBondContact O-N 2.74Å; I17-K20 PolarHBondContact O-N 2.79Å; K20-I23 CarbonylContact O-C 3.56Å; K20-I23 PolarHBondContact O-N 3.49Å; K20-H24 WeakPolarHBondContact O-CA 3.41Å; K20-H24 WeakPolarHBondContact O-CB 3.49Å; K20-H24 PolarHBondContact O-N 3.48Å
21	N	38.1	Very low	38.4	Very low	102 Å²	102	91.7 Å²	91.7	55%	0.545	44%	0.44	S	S	.	.	H	α-helix	trans	-69.4	-39.1	171.1	-74.8	-5.7	0	0	0	110.5	I17 I23 N25	I17-N21 WeakPolarHBondContact CG2-ND2 3.43Å; I17-N21 WeakPolarHBondContact O-CA 3.37Å; I17-N21 WeakPolarHBondContact O-CB 3.18Å; I17-N21 PolarHBondContact O-N 2.99Å; N21-I23 VanDerWaalsContact C-N 3.33Å; N21-N25 VanDerWaalsContact O-CB 3.27Å; N21-N25 WeakPolarHBondContact O-CB 3.43Å; N21-N25 PolarHBondContact O-N 2.98Å
22	V	41.5	Very low	38.1	Very low	58 Å²	58	95.7 Å²	95.7	35%	0.352	46%	0.455	S	S	.	.	H	α-helix	trans	-63.1	-40.5	171	169.5	0	0	0	0	110.8	K18 L19 Y28 Y34	K18-V22 VanDerWaalsContact O-CB 3.25Å; K18-V22 WeakPolarHBondContact O-CB 3.5Å; K18-V22 WeakPolarHBondContact O-CG2 3.39Å; K18-V22 PolarHBondContact O-N 3.49Å; L19-V22 PolarHBondContact O-N 2.88Å; V22-Y28 WeakPolarHBondContact O-CB 3.4Å; V22-Y34 WeakPolarHBondContact CG1-OH 3.43Å
23	I	35.9	Very low	38	Very low	73 Å²	73	97.3 Å²	97.3	37%	0.374	47%	0.465	S	S	.	.	H	α-helix	trans	-78	-28.8	179.4	-67	162.1	0	0	0	113.5	L19 K20 N21 Q29	L19-I23 HydrophobicContact CD2-CD1 3.62Å; L19-I23 HydrophobicContact CG-CD1 3.87Å; L19-I23 VanDerWaalsContact O-CB 3.3Å; L19-I23 WeakPolarHBondContact O-CB 3.43Å; L19-I23 VanDerWaalsContact O-CD1 3.28Å; L19-I23 WeakPolarHBondContact O-CD1 3.34Å; L19-I23 WeakPolarHBondContact O-CG1 3.31Å; L19-I23 PolarHBondContact O-N 3.38Å; K20-I23 CarbonylContact O-C 3.56Å; K20-I23 PolarHBondContact O-N 3.49Å; N21-I23 VanDerWaalsContact C-N 3.33Å; I23-Q29 WeakPolarHBondContact O-CG 3.42Å; I23-Q29 PolarHBondContact O-NE2 3.09Å
24	H	33.2	Very low	37.8	Very low	106 Å²	106	97.4 Å²	97.4	49%	0.491	47%	0.466	S	S	.	.	H	α-helix	trans	-104.6	-5.6	-176.4	-73.8	8.5	0	0	0	114	K20 K26	K20-H24 WeakPolarHBondContact O-CA 3.41Å; K20-H24 WeakPolarHBondContact O-CB 3.49Å; K20-H24 PolarHBondContact O-N 3.48Å; H24-K26 PolarHBondContact O-N 2.93Å
25	N	35.1	Very low	37.6	Very low	83 Å²	83	100.2 Å²	100.2	44%	0.444	49%	0.486	S	S	.	.			trans	-59.7	120	170.9	-137.6	-16.6	0	0	0	107.6	N21 S27 Y28 Q29	N21-N25 VanDerWaalsContact O-CB 3.27Å; N21-N25 WeakPolarHBondContact O-CB 3.43Å; N21-N25 PolarHBondContact O-N 2.98Å; N25-S27 PolarHBondContact O-N 3.18Å; N25-Y28 HydrophobicContact CB-CD2 3.75Å; N25-Y28 HydrophobicContact CB-CG 4.35Å; N25-Y28 CarbonylContact O-C 3.24Å; N25-Y28 WeakPolarHBondContact O-CA 3.4Å; N25-Y28 WeakPolarHBondContact O-CB 3.27Å; N25-Y28 PolarHBondContact O-N 3.13Å; N25-Q29 PolarHBondContact O-N 3.39Å
26	K	32.7	Very low	37.1	Very low	156 Å²	156	101.7 Å²	101.7	68%	0.678	50%	0.496	S	S	*	.	H	α-helix	trans	-59.6	-32.7	177.8	-80.1	-175.9	173.4	-176.6	0	111.6	H24 Y28 Q29 E30	H24-K26 PolarHBondContact O-N 2.93Å; K26-Y28 PolarHBondContact O-N 3.36Å; K26-Q29 PolarHBondContact O-N 3.11Å; K26-E30 WeakPolarHBondContact O-CG 3.4Å; K26-E30 PolarHBondContact O-N 3.06Å
27	S	43.6	Very low	36.9	Very low	74 Å²	74	100.1 Å²	100.1	52%	0.517	50%	0.497	S	S	.	.	H	α-helix	trans	-62.7	-23.3	172.4	63.5	0	0	0	0	113.5	N25	N25-S27 PolarHBondContact O-N 3.18Å
28	Y	38.2	Very low	36.8	Very low	111 Å²	111	102.1 Å²	102.1	44%	0.435	51%	0.507	S	S	.	.	H	α-helix	trans	-95.5	-26.6	175.5	-85.7	-87.8	0	0	0	112.8	V22 N25 K26 Y34	V22-Y28 WeakPolarHBondContact O-CB 3.4Å; N25-Y28 HydrophobicContact CB-CD2 3.75Å; N25-Y28 HydrophobicContact CB-CG 4.35Å; N25-Y28 CarbonylContact O-C 3.24Å; N25-Y28 WeakPolarHBondContact O-CA 3.4Å; N25-Y28 WeakPolarHBondContact O-CB 3.27Å; N25-Y28 PolarHBondContact O-N 3.13Å; K26-Y28 PolarHBondContact O-N 3.36Å; Y28-Y34 AromaticContact CD1-CE2 3.94Å; Y28-Y34 HydrophobicContact CD1-CE2 3.94Å
29	Q	32.8	Very low	36.4	Very low	109 Å²	109	98.4 Å²	98.4	51%	0.509	50%	0.498	S	S	.	.	H	α-helix	trans	-77.4	-26.5	174.3	-70.9	-172.3	-16.6	0	0	113.6	I23 N25 K26 N31	I23-Q29 WeakPolarHBondContact O-CG 3.42Å; I23-Q29 PolarHBondContact O-NE2 3.09Å; N25-Q29 PolarHBondContact O-N 3.39Å; K26-Q29 PolarHBondContact O-N 3.11Å; Q29-N31 PolarHBondContact O-N 3.06Å
30	E	36.3	Very low	36.1	Very low	156 Å²	156	99.6 Å²	99.6	73%	0.729	50%	0.501	S	S	*	.	S	Bend	trans	-67.6	-14.2	173.6	-76.8	177.8	-177.9	0	0	112.5	K26 I32	K26-E30 WeakPolarHBondContact O-CG 3.4Å; K26-E30 PolarHBondContact O-N 3.06Å; E30-I32 PolarHBondContact O-N 3.01Å
31	N	36.8	Very low	36.2	Very low	93 Å²	93	101.1 Å²	101.1	50%	0.497	52%	0.515	S	S	.	.			trans	-79.4	93.8	161.3	-78.6	-12	0	0	0	109.4	Q29 N33 Y34	Q29-N31 PolarHBondContact O-N 3.06Å; N31-N33 PolarHBondContact O-N 3.29Å; N31-Y34 PolarHBondContact O-N 2.93Å
32	I	35.6	Very low	36.4	Very low	149 Å²	149	98.3 Å²	98.3	76%	0.764	50%	0.503	S	S	*	.	T	Hydrogen-bonded Turn	trans	-51.1	-17	169.6	-65.7	169.2	0	0	0	112	E30 Y34	E30-I32 PolarHBondContact O-N 3.01Å; I32-Y34 VanDerWaalsContact C-N 3.35Å; I32-Y34 PolarHBondContact O-N 3.11Å
33	N	38.3	Very low	36.7	Very low	83 Å²	83	100.1 Å²	100.1	44%	0.444	52%	0.518	S	S	.	.	T	Hydrogen-bonded Turn	trans	-78	0.5	176.7	-69.9	16.6	0	0	0	115.2	N31 T35 E36 D37	N31-N33 PolarHBondContact O-N 3.29Å; N33-T35 PolarHBondContact O-N 2.75Å; N33-E36 CarbonylContact O-C 3.41Å; N33-E36 WeakPolarHBondContact O-CA 3.43Å; N33-E36 WeakPolarHBondContact O-CB 3.31Å; N33-E36 PolarHBondContact O-N 3.38Å; N33-D37 WeakPolarHBondContact O-CB 3.38Å; N33-D37 PolarHBondContact O-N 3.29Å
34	Y	33.5	Very low	37.3	Very low	70 Å²	70	102.6 Å²	102.6	28%	0.275	53%	0.532	S	S	.	.	H	α-helix	trans	-69	-32.1	-174.4	-146.7	-85.1	0	0	0	114.6	V22 Y28 N31 I32 D37 L38	V22-Y34 WeakPolarHBondContact CG1-OH 3.43Å; Y28-Y34 AromaticContact CD1-CE2 3.94Å; Y28-Y34 HydrophobicContact CD1-CE2 3.94Å; N31-Y34 PolarHBondContact O-N 2.93Å; I32-Y34 VanDerWaalsContact C-N 3.35Å; I32-Y34 PolarHBondContact O-N 3.11Å; Y34-D37 PolarHBondContact O-N 2.94Å; Y34-L38 HydrophobicContact CD1-CD1 3.96Å; Y34-L38 HydrophobicContact CD1-CG 4.32Å; Y34-L38 HydrophobicContact CE1-CD1 3.87Å; Y34-L38 HydrophobicContact CE1-CG 4.13Å; Y34-L38 PolarHBondContact O-N 3.39Å
35	T	33.4	Very low	38	Very low	117 Å²	117	100 Å²	100	72%	0.718	52%	0.521	S	S	*	.	H	α-helix	trans	-68.4	-28.7	168.9	35.9	0	0	0	0	111.9	N33 S39	N33-T35 PolarHBondContact O-N 2.75Å; T35-S39 WeakPolarHBondContact O-CB 3.39Å; T35-S39 PolarHBondContact O-N 2.86Å; T35-S39 PolarHBondContact O-OG 2.99Å; T35-S39 VanDerWaalsContact O-OG 3.05Å
36	E	34.4	Very low	38.8	Very low	121 Å²	121	97.3 Å²	97.3	57%	0.565	51%	0.505	S	S	*	.	H	α-helix	trans	-76.5	-35.8	173.8	-67.3	-176.7	169	0	0	112.2	N33 L38 S39	N33-E36 CarbonylContact O-C 3.41Å; N33-E36 WeakPolarHBondContact O-CA 3.43Å; N33-E36 WeakPolarHBondContact O-CB 3.31Å; N33-E36 PolarHBondContact O-N 3.38Å; E36-L38 PolarHBondContact O-N 3.1Å; E36-S39 WeakPolarHBondContact CA-OG 3.32Å; E36-S39 CarbonylContact O-C 3.58Å; E36-S39 VanDerWaalsContact O-C 3.24Å; E36-S39 PolarHBondContact O-N 3.44Å; E36-S39 PolarHBondContact O-OG 2.86Å
37	D	37.8	Very low	39.9	Very low	92 Å²	92	92.9 Å²	92.9	49%	0.492	49%	0.493	S	S	.	.	H	α-helix	trans	-75	-23.7	-179.5	-75.7	-26.8	0	0	0	112.7	N33 Y34 F40	N33-D37 WeakPolarHBondContact O-CB 3.38Å; N33-D37 PolarHBondContact O-N 3.29Å; Y34-D37 PolarHBondContact O-N 2.94Å; D37-F40 WeakPolarHBondContact O-CE2 3.29Å
38	L	35.1	Very low	40.4	Very low	78 Å²	78	93.5 Å²	93.5	41%	0.408	49%	0.488	S	S	.	.	H	α-helix	trans	-84.6	-29	167.5	-76.1	169	0	0	0	112	Y34 E36 F40	Y34-L38 HydrophobicContact CD1-CD1 3.96Å; Y34-L38 HydrophobicContact CD1-CG 4.32Å; Y34-L38 HydrophobicContact CE1-CD1 3.87Å; Y34-L38 HydrophobicContact CE1-CG 4.13Å; Y34-L38 PolarHBondContact O-N 3.39Å; E36-L38 PolarHBondContact O-N 3.1Å; L38-F40 PolarHBondContact O-N 3.38Å
39	S	32.5	Very low	41.3	Very low	53 Å²	53	88.6 Å²	88.6	37%	0.371	47%	0.469	S	S	.	.	S	Bend	trans	-84.2	81.4	171.9	67.5	0	0	0	0	110.1	T35 E36 D41	T35-S39 WeakPolarHBondContact O-CB 3.39Å; T35-S39 PolarHBondContact O-N 2.86Å; T35-S39 PolarHBondContact O-OG 2.99Å; T35-S39 VanDerWaalsContact O-OG 3.05Å; E36-S39 WeakPolarHBondContact CA-OG 3.32Å; E36-S39 CarbonylContact O-C 3.58Å; E36-S39 VanDerWaalsContact O-C 3.24Å; E36-S39 PolarHBondContact O-N 3.44Å; E36-S39 PolarHBondContact O-OG 2.86Å; S39-D41 PolarHBondContact O-N 3.09Å
40	F	37.2	Very low	42.3	Very low	84 Å²	84	90.7 Å²	90.7	37%	0.368	48%	0.479	S	S	.	.			trans	-62.1	101.8	167.3	-78	-87.1	0	0	0	109.5	D37 L38 S42 Y46	D37-F40 WeakPolarHBondContact O-CE2 3.29Å; L38-F40 PolarHBondContact O-N 3.38Å; F40-S42 PolarHBondContact O-N 3.49Å; F40-S42 VanDerWaalsContact O-N 3.11Å; F40-Y46 HydrophobicContact CB-CE2 3.98Å
41	D	38	Very low	43.4	Very low	156 Å²	156	88.9 Å²	88.9	83%	0.834	47%	0.474	S	S	*	.			trans	-64.2	-10.4	178.2	-94.4	-23	0	0	0	113.3	S39 S43	S39-D41 PolarHBondContact O-N 3.09Å; D41-S43 PolarHBondContact O-N 2.68Å; D41-S43 VanDerWaalsContact O-N 3.14Å
42	S	41.6	Very low	44.6	Very low	43 Å²	43	84.7 Å²	84.7	30%	0.301	45%	0.451	S	S	.	.			trans	-87.2	86.2	176.5	68.3	0	0	0	0	111.9	F40 L44 L45	F40-S42 PolarHBondContact O-N 3.49Å; F40-S42 VanDerWaalsContact O-N 3.11Å; S42-L44 PolarHBondContact O-N 3.33Å; S42-L45 PolarHBondContact O-N 3.42Å
43	S	48.4	Very low	45.5	Very low	96 Å²	96	82.9 Å²	82.9	67%	0.671	44%	0.44	S	S	*	.	H	α-helix	trans	-49.7	-21.1	161.4	55.6	0	0	0	0	113.6	D41 S47	D41-S43 PolarHBondContact O-N 2.68Å; D41-S43 VanDerWaalsContact O-N 3.14Å; S43-S47 WeakPolarHBondContact O-CB 3.31Å; S43-S47 PolarHBondContact O-N 3.35Å; S43-S47 PolarHBondContact O-OG 3.49Å
44	L	48	Very low	46.6	Very low	124 Å²	124	81.8 Å²	81.8	65%	0.649	44%	0.438	S	S	*	.	H	α-helix	trans	-71.9	-36.3	-175.5	-129.9	142.7	0	0	0	114.4	S42 S47 Q48	S42-L44 PolarHBondContact O-N 3.33Å; L44-S47 PolarHBondContact O-OG 2.98Å; L44-Q48 WeakPolarHBondContact O-CG 3.41Å
45	L	49	Very low	48.2	Very low	51 Å²	51	79 Å²	79	27%	0.267	43%	0.428	S	S	.	.	H	α-helix	trans	-71.7	-38.7	174.9	-92.5	155.2	0	0	0	110.9	S42 F49 I82	S42-L45 PolarHBondContact O-N 3.42Å; L45-F49 VanDerWaalsContact O-CD2 3.29Å; L45-F49 WeakPolarHBondContact O-CD2 3.41Å; L45-F49 VanDerWaalsContact O-CE2 3.24Å; L45-F49 WeakPolarHBondContact O-CE2 3.33Å; L45-I82 HydrophobicContact CD2-CG1 4.09Å
46	Y	52	Low	49.9	Very low	27 Å²	27	75.8 Å²	75.8	11%	0.106	41%	0.409	C	S	.	.	H	α-helix	trans	-73.6	-33.5	178.9	-72.5	-76.5	0	0	0	113.6	F40 Q48 F49 Q88 C89 I104 C106	F40-Y46 HydrophobicContact CB-CE2 3.98Å; Y46-Q48 PolarHBondContact O-N 3.25Å; Y46-F49 HydrophobicContact CD1-CD2 4.47Å; Y46-F49 PolarHBondContact O-N 3.21Å; Y46-F49 VanDerWaalsContact O-N 3.09Å; Y46-Q88 PolarHBondContact OH-OE1 3.03Å; Y46-C89 WeakPolarHBondContact CE1-SG 3.14Å; Y46-I104 HydrophobicContact CD1-CG2 4.06Å; Y46-I104 HydrophobicContact CE1-CD1 4.02Å; Y46-I104 HydrophobicContact CE1-CG1 4.22Å; Y46-I104 HydrophobicContact CE1-CG2 3.8Å; Y46-I104 HydrophobicContact CE2-CG1 4.44Å; Y46-I104 WeakPolarHBondContact OH-CD1 3.25Å; Y46-C106 HydrophobicContact CD1-CB 4.28Å
47	S	54.5	Low	51.7	Low	63 Å²	63	70.2 Å²	70.2	44%	0.441	38%	0.382	S	S	.	.	H	α-helix	trans	-64.6	-27.7	179	65.2	0	0	0	0	112.5	S43 L44 F49 H50	S43-S47 WeakPolarHBondContact O-CB 3.31Å; S43-S47 PolarHBondContact O-N 3.35Å; S43-S47 PolarHBondContact O-OG 3.49Å; L44-S47 PolarHBondContact O-OG 2.98Å; S47-F49 PolarHBondContact O-N 3.39Å; S47-H50 PolarHBondContact O-N 2.85Å
48	Q	54.9	Low	53.3	Low	87 Å²	87	66.2 Å²	66.2	41%	0.407	36%	0.362	S	S	.	.	G	3₁₀ helix	trans	-63.1	-26.4	173.7	-68.8	176.1	-4.5	0	0	112.6	L44 Y46 H50 I55 I76	L44-Q48 WeakPolarHBondContact O-CG 3.41Å; Y46-Q48 PolarHBondContact O-N 3.25Å; Q48-H50 VanDerWaalsContact C-N 3.33Å; Q48-H50 PolarHBondContact O-N 3.38Å; Q48-I55 WeakPolarHBondContact O-CD1 3.49Å; Q48-I76 HydrophobicContact CB-CD1 4.13Å
49	F	56.6	Low	54.6	Low	8 Å²	8	63.8 Å²	63.8	4%	0.035	35%	0.349	C	S	.	.	G	3₁₀ helix	trans	-84.8	3.6	-177	-59.8	-58.4	0	0	0	114.9	L45 Y46 S47 N51 F52 I55 I76 I82 C85 I86	L45-F49 VanDerWaalsContact O-CD2 3.29Å; L45-F49 WeakPolarHBondContact O-CD2 3.41Å; L45-F49 VanDerWaalsContact O-CE2 3.24Å; L45-F49 WeakPolarHBondContact O-CE2 3.33Å; Y46-F49 HydrophobicContact CD1-CD2 4.47Å; Y46-F49 PolarHBondContact O-N 3.21Å; Y46-F49 VanDerWaalsContact O-N 3.09Å; S47-F49 PolarHBondContact O-N 3.39Å; F49-N51 PolarHBondContact O-N 3.45Å; F49-F52 AromaticContact CD1-CD2 3.58Å; F49-F52 HydrophobicContact CD1-CD2 3.58Å; F49-F52 AromaticContact CD1-CE2 3.58Å; F49-F52 HydrophobicContact CD1-CE2 3.58Å; F49-F52 HydrophobicContact CE1-CD2 4.27Å; F49-F52 AromaticContact CE1-CE2 3.78Å; F49-F52 HydrophobicContact CE1-CE2 3.78Å; F49-F52 HydrophobicContact CG-CD2 4.44Å; F49-I55 HydrophobicContact CD1-CD1 4.44Å; F49-I76 HydrophobicContact CE1-CD1 4.18Å; F49-I82 HydrophobicContact CZ-CG2 4.44Å; F49-C85 HydrophobicContact CE2-CB 3.99Å; F49-C85 HydrophobicContact CZ-CB 4.35Å; F49-I86 HydrophobicContact CE1-CD1 4.35Å; F49-I86 HydrophobicContact CE1-CG1 3.94Å; F49-I86 HydrophobicContact CZ-CG1 4Å
50	H	53.8	Low	56	Low	154 Å²	154	65 Å²	65	71%	0.713	35%	0.351	S	S	*	.	G	3₁₀ helix	trans	-60.5	-26.5	-179	-98.8	-59.9	0	0	0	114	S47 Q48	S47-H50 PolarHBondContact O-N 2.85Å; Q48-H50 VanDerWaalsContact C-N 3.33Å; Q48-H50 PolarHBondContact O-N 3.38Å
51	N	60.2	Low	56.8	Low	118 Å²	118	67 Å²	67	63%	0.631	36%	0.357	S	S	*	.	G	3₁₀ helix	trans	-134.6	64.1	175.9	-79.9	-23.4	0	0	0	111.6	F49 E53 S54	F49-N51 PolarHBondContact O-N 3.45Å; N51-E53 PolarHBondContact O-N 2.93Å; N51-E53 VanDerWaalsContact O-N 3.07Å; N51-S54 VanDerWaalsContact CB-OG 3.3Å; N51-S54 WeakPolarHBondContact CB-OG 3.41Å; N51-S54 PolarHBondContact O-N 3.18Å; N51-S54 PolarHBondContact O-OG 2.89Å
52	F	61.4	Low	57.5	Low	4 Å²	4	67.5 Å²	67.5	2%	0.018	35%	0.354	C	S	.	.	G	3₁₀ helix	trans	-50.4	-36.6	-177.2	-154.1	-79.4	0	0	0	114	F49 S54 I55 F57 I86 L113	F49-F52 AromaticContact CD1-CD2 3.58Å; F49-F52 HydrophobicContact CD1-CD2 3.58Å; F49-F52 AromaticContact CD1-CE2 3.58Å; F49-F52 HydrophobicContact CD1-CE2 3.58Å; F49-F52 HydrophobicContact CE1-CD2 4.27Å; F49-F52 AromaticContact CE1-CE2 3.78Å; F49-F52 HydrophobicContact CE1-CE2 3.78Å; F49-F52 HydrophobicContact CG-CD2 4.44Å; F52-S54 PolarHBondContact O-N 3.49Å; F52-I55 HydrophobicContact CD2-CD1 4.48Å; F52-I55 WeakPolarHBondContact O-CB 3.49Å; F52-I55 PolarHBondContact O-N 3.47Å; F52-I55 VanDerWaalsContact O-N 3.13Å; F52-F57 AromaticContact CD1-CE2 3.98Å; F52-F57 HydrophobicContact CD1-CE2 3.98Å; F52-F57 HydrophobicContact CD1-CZ 4.14Å; F52-F57 HydrophobicContact CD2-CZ 4.34Å; F52-F57 HydrophobicContact CE1-CD2 4.33Å; F52-F57 HydrophobicContact CE1-CE1 4.45Å; F52-F57 AromaticContact CE1-CE2 3.23Å; F52-F57 HydrophobicContact CE1-CE2 3.23Å; F52-F57 AromaticContact CE1-CZ 3.33Å; F52-F57 HydrophobicContact CE1-CZ 3.33Å; F52-F57 HydrophobicContact CE2-CE1 4.36Å; F52-F57 HydrophobicContact CE2-CE2 4.35Å; F52-F57 AromaticContact CE2-CZ 3.58Å; F52-F57 HydrophobicContact CE2-CZ 3.58Å; F52-F57 AromaticContact CZ-CE1 3.83Å; F52-F57 HydrophobicContact CZ-CE1 3.83Å; F52-F57 AromaticContact CZ-CE2 3.46Å; F52-F57 HydrophobicContact CZ-CE2 3.46Å; F52-F57 VanDerWaalsContact CZ-CE2 3.46Å; F52-F57 AromaticContact CZ-CZ 2.98Å; F52-F57 HydrophobicContact CZ-CZ 2.98Å; F52-I86 HydrophobicContact CE2-CD1 4.09Å; F52-I86 HydrophobicContact CE2-CG1 4.13Å; F52-I86 HydrophobicContact CZ-CD1 4.03Å; F52-L113 HydrophobicContact CD1-CD2 3.78Å; F52-L113 HydrophobicContact CD2-CD2 3.95Å; F52-L113 HydrophobicContact CE1-CD2 3.2Å; F52-L113 HydrophobicContact CE1-CG 4.42Å; F52-L113 HydrophobicContact CE2-CD2 3.39Å; F52-L113 HydrophobicContact CG-CD2 4.14Å; F52-L113 HydrophobicContact CZ-CD2 2.97Å; F52-L113 HydrophobicContact CZ-CG 4.43Å
53	E	55.3	Low	58	Low	111 Å²	111	71.9 Å²	71.9	52%	0.519	37%	0.37	S	S	.	.	G	3₁₀ helix	trans	-64.8	-21.5	179.7	-62.4	-172.5	152.2	0	0	114	N51 R115	N51-E53 PolarHBondContact O-N 2.93Å; N51-E53 VanDerWaalsContact O-N 3.07Å; E53-R115 IonicContact OE1-CZ 3.4Å; E53-R115 IonicContact OE1-NE 3.93Å; E53-R115 IonicContact OE1-NH1 3.55Å; E53-R115 PolarHBondContact OE1-NH1 3.04Å; E53-R115 IonicContact OE2-NH1 3.19Å
54	S	61.9	Low	58.1	Low	60 Å²	60	70.1 Å²	70.1	42%	0.42	35%	0.349	S	S	.	.	G	3₁₀ helix	trans	-92.7	-2.6	178.1	68.3	0	0	0	0	113.7	N51 F52	N51-S54 VanDerWaalsContact CB-OG 3.3Å; N51-S54 WeakPolarHBondContact CB-OG 3.41Å; N51-S54 PolarHBondContact O-N 3.18Å; N51-S54 PolarHBondContact O-OG 2.89Å; F52-S54 PolarHBondContact O-N 3.49Å
55	I	66.7	Low	58.2	Low	12 Å²	12	68.4 Å²	68.4	6%	0.062	34%	0.339	C	S	.	.			trans	-92.4	127	-176.7	-55.7	171.9	0	0	0	109.5	Q48 F49 F52 F57 K74 I76	Q48-I55 WeakPolarHBondContact O-CD1 3.49Å; F49-I55 HydrophobicContact CD1-CD1 4.44Å; F52-I55 HydrophobicContact CD2-CD1 4.48Å; F52-I55 WeakPolarHBondContact O-CB 3.49Å; F52-I55 PolarHBondContact O-N 3.47Å; F52-I55 VanDerWaalsContact O-N 3.13Å; I55-F57 HydrophobicContact CB-CE2 3.88Å; I55-F57 HydrophobicContact CB-CZ 4.01Å; I55-F57 HydrophobicContact CG2-CD2 4.28Å; I55-F57 HydrophobicContact CG2-CE1 4.08Å; I55-F57 HydrophobicContact CG2-CE2 3.71Å; I55-F57 HydrophobicContact CG2-CZ 3.56Å; I55-K74 WeakPolarHBondContact CA-O 3.29Å; I55-I76 HydrophobicContact CD1-CD1 3.9Å; I55-I76 HydrophobicContact CG2-CB 3.93Å; I55-I76 HydrophobicContact CG2-CD1 3.68Å; I55-I76 HydrophobicContact CG2-CG1 3.57Å
56	T	67.8	Low	58.3	Low	50 Å²	50	72.7 Å²	72.7	31%	0.307	36%	0.362	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-89.4	137	168.3	54.3	0	0	0	0	109.5	K74 H75 I76	T56-K74 PolarHBondContact N-O 2.93Å; T56-K74 PolarHBondContact OG1-O 3.41Å; T56-H75 WeakPolarHBondContact O-CA 3.39Å; T56-H75 PolarHBondContact O-ND1 3.06Å; T56-H75 VanDerWaalsContact O-ND1 3.11Å; T56-H75 PolarHBondContact OG1-ND1 3Å; T56-I76 PolarHBondContact O-N 2.72Å
57	F	72.7	Confident	58.5	Low	3 Å²	3	77.8 Å²	77.8	1%	0.013	39%	0.385	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-113	132.5	-179.1	-68.2	-87.7	0	0	0	109.8	F52 I55 I76 I78 I86 F119	F52-F57 AromaticContact CD1-CE2 3.98Å; F52-F57 HydrophobicContact CD1-CE2 3.98Å; F52-F57 HydrophobicContact CD1-CZ 4.14Å; F52-F57 HydrophobicContact CD2-CZ 4.34Å; F52-F57 HydrophobicContact CE1-CD2 4.33Å; F52-F57 HydrophobicContact CE1-CE1 4.45Å; F52-F57 AromaticContact CE1-CE2 3.23Å; F52-F57 HydrophobicContact CE1-CE2 3.23Å; F52-F57 AromaticContact CE1-CZ 3.33Å; F52-F57 HydrophobicContact CE1-CZ 3.33Å; F52-F57 HydrophobicContact CE2-CE1 4.36Å; F52-F57 HydrophobicContact CE2-CE2 4.35Å; F52-F57 AromaticContact CE2-CZ 3.58Å; F52-F57 HydrophobicContact CE2-CZ 3.58Å; F52-F57 AromaticContact CZ-CE1 3.83Å; F52-F57 HydrophobicContact CZ-CE1 3.83Å; F52-F57 AromaticContact CZ-CE2 3.46Å; F52-F57 HydrophobicContact CZ-CE2 3.46Å; F52-F57 VanDerWaalsContact CZ-CE2 3.46Å; F52-F57 AromaticContact CZ-CZ 2.98Å; F52-F57 HydrophobicContact CZ-CZ 2.98Å; I55-F57 HydrophobicContact CB-CE2 3.88Å; I55-F57 HydrophobicContact CB-CZ 4.01Å; I55-F57 HydrophobicContact CG2-CD2 4.28Å; I55-F57 HydrophobicContact CG2-CE1 4.08Å; I55-F57 HydrophobicContact CG2-CE2 3.71Å; I55-F57 HydrophobicContact CG2-CZ 3.56Å; F57-I76 WeakPolarHBondContact CA-O 3.38Å; F57-I76 HydrophobicContact CD1-CB 4.09Å; F57-I76 HydrophobicContact CD1-CG2 4.23Å; F57-I76 HydrophobicContact CE1-CB 3.95Å; F57-I76 HydrophobicContact CE1-CD1 4.38Å; F57-I76 HydrophobicContact CE1-CG2 4.04Å; F57-I78 HydrophobicContact CB-CD1 3.76Å; F57-I78 HydrophobicContact CB-CG1 4.15Å; F57-I78 HydrophobicContact CD1-CD1 4.03Å; F57-I78 HydrophobicContact CD1-CG1 3.76Å; F57-I78 HydrophobicContact CG-CD1 4.23Å; F57-I78 HydrophobicContact CG-CG1 4.39Å; F57-I86 HydrophobicContact CE1-CD1 4.46Å; F57-F119 HydrophobicContact CB-CB 4.36Å; F57-F119 HydrophobicContact CB-CD2 4.49Å; F57-F119 AromaticContact CD1-CD2 3.98Å; F57-F119 HydrophobicContact CD1-CD2 3.98Å; F57-F119 HydrophobicContact CD2-CB 3.82Å; F57-F119 HydrophobicContact CD2-CD2 4.14Å; F57-F119 HydrophobicContact CD2-CG 4.37Å; F57-F119 HydrophobicContact CE1-CD2 4.28Å; F57-F119 HydrophobicContact CE2-CB 4.46Å; F57-F119 HydrophobicContact CE2-CD2 4.45Å; F57-F119 HydrophobicContact CG-CB 4.14Å; F57-F119 AromaticContact CG-CD2 3.91Å; F57-F119 HydrophobicContact CG-CD2 3.91Å
58	S	72.2	Confident	58.3	Low	8 Å²	8	82.8 Å²	82.8	6%	0.056	41%	0.406	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-136.9	167.2	172	76.6	0	0	0	0	112.9	H75 I76 T77 I78	S58-H75 WeakPolarHBondContact CB-CE1 3.3Å; S58-H75 WeakPolarHBondContact CB-NE2 3.27Å; S58-H75 PolarHBondContact OG-CE1 2.98Å; S58-H75 PolarHBondContact OG-NE2 3.43Å; S58-I76 PolarHBondContact N-O 2.85Å; S58-T77 CarbonylContact O-C 3.22Å; S58-T77 WeakPolarHBondContact O-CA 3.27Å; S58-I78 PolarHBondContact O-N 2.98Å
59	M	62.3	Low	58.1	Low	28 Å²	28	86.6 Å²	86.6	14%	0.138	43%	0.43	C	S	.	.	S	Bend	trans	-89.1	-34.3	169.2	-65.7	-56.4	-48.2	0	0	112.9	I78 C122 I126 Y131 F136	M59-I78 HydrophobicContact SD-CB 4.37Å; M59-C122 HydrophobicContact CG-CB 4.48Å; M59-C122 HydrophobicContact SD-CB 4.2Å; M59-I126 HydrophobicContact CE-CD1 4.13Å; M59-I126 HydrophobicContact CE-CG1 3.73Å; M59-I126 HydrophobicContact SD-CD1 3.54Å; M59-I126 VanDerWaalsContact SD-CD1 3.54Å; M59-I126 HydrophobicContact SD-CG1 3.47Å; M59-I126 WeakPolarHBondContact SD-CG1 3.4Å; M59-Y131 HydrophobicContact CE-CD2 3.77Å; M59-Y131 HydrophobicContact CE-CE2 3.27Å; M59-Y131 HydrophobicContact SD-CE2 4.28Å; M59-F136 HydrophobicContact CE-CE1 3.81Å; M59-F136 HydrophobicContact CE-CZ 3.9Å
60	D	62.1	Low	57.7	Low	78 Å²	78	88.8 Å²	88.8	42%	0.417	44%	0.438	S	S	.	.			trans	-111.1	107.6	-171.7	-69.4	-20.9	0	0	0	111.2	E62 Q63	D60-E62 VanDerWaalsContact C-N 3.26Å; D60-E62 PolarHBondContact O-N 2.9Å; D60-Q63 HydrophobicContact CB-CB 4.29Å; D60-Q63 HydrophobicContact CB-CG 4.12Å; D60-Q63 PolarHBondContact OD2-NE2 3.09Å
61	Y	53.4	Low	57.8	Low	127 Å²	127	85 Å²	85	50%	0.498	42%	0.423	S	S	.	.	H	α-helix	trans	-61.4	-35.8	173.6	-166.6	-98.1	0	0	0	111.9	M65 T77	Y61-M65 HydrophobicContact CD1-CG 4.39Å; Y61-M65 HydrophobicContact CE1-CE 3.52Å; Y61-M65 HydrophobicContact CE1-CG 4.09Å; Y61-M65 WeakPolarHBondContact OH-CE 3Å; Y61-T77 WeakPolarHBondContact CD2-OG1 3.42Å
62	E	51.8	Low	57.4	Low	166 Å²	166	82.3 Å²	82.3	78%	0.776	41%	0.413	S	S	*	.	H	α-helix	trans	-71.3	-31.7	-173.6	-66.1	-171.3	166.9	0	0	114	D60 Y64	D60-E62 VanDerWaalsContact C-N 3.26Å; D60-E62 PolarHBondContact O-N 2.9Å; E62-Y64 VanDerWaalsContact C-N 3.27Å; E62-Y64 PolarHBondContact O-N 2.71Å
63	Q	52.3	Low	57.2	Low	134 Å²	134	86.7 Å²	86.7	63%	0.626	44%	0.444	S	S	*	.	H	α-helix	trans	-67.4	-28.5	-178.5	-79.2	-171.5	4.8	0	0	113.1	D60	D60-Q63 HydrophobicContact CB-CB 4.29Å; D60-Q63 HydrophobicContact CB-CG 4.12Å; D60-Q63 PolarHBondContact OD2-NE2 3.09Å
64	Y	50.3	Low	57.6	Low	59 Å²	59	86.4 Å²	86.4	23%	0.231	44%	0.441	C	S	.	.	H	α-helix	trans	-93.8	-24.9	-172.3	-81.9	-85.6	0	0	0	114.4	E62 N66 K67 Y70 H75	E62-Y64 VanDerWaalsContact C-N 3.27Å; E62-Y64 PolarHBondContact O-N 2.71Å; Y64-N66 PolarHBondContact O-N 2.97Å; Y64-K67 PolarHBondContact O-N 3.29Å; Y64-Y70 VanDerWaalsContact CB-OH 3.24Å; Y64-Y70 WeakPolarHBondContact CB-OH 3.46Å; Y64-Y70 HydrophobicContact CD1-CD2 4.25Å; Y64-Y70 AromaticContact CD1-CE2 3.37Å; Y64-Y70 HydrophobicContact CD1-CE2 3.37Å; Y64-Y70 AromaticContact CD1-CZ 3.66Å; Y64-Y70 WeakPolarHBondContact CD1-OH 3.44Å; Y64-Y70 HydrophobicContact CE1-CE2 4.27Å; Y64-Y70 AromaticContact CG-CE2 3.91Å; Y64-Y70 HydrophobicContact CG-CE2 3.91Å; Y64-Y70 AromaticContact CG-CZ 3.74Å; Y64-H75 AromaticContact CD2-NE2 3.96Å
65	M	49.9	Very low	57.8	Low	89 Å²	89	84.5 Å²	84.5	44%	0.438	43%	0.426	S	S	.	.	H	α-helix	trans	-60.4	-24.4	173.8	-83.8	-69.1	-166.7	0	0	113.3	Y61 K67	Y61-M65 HydrophobicContact CD1-CG 4.39Å; Y61-M65 HydrophobicContact CE1-CE 3.52Å; Y61-M65 HydrophobicContact CE1-CG 4.09Å; Y61-M65 WeakPolarHBondContact OH-CE 3Å; M65-K67 PolarHBondContact O-N 2.96Å; M65-K67 VanDerWaalsContact O-N 3.17Å
66	N	53.1	Low	57.9	Low	141 Å²	141	84.4 Å²	84.4	75%	0.754	43%	0.425	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.9	4.3	179	-76.5	-20.4	0	0	0	114.4	Y64	Y64-N66 PolarHBondContact O-N 2.97Å
67	K	54.5	Low	58.3	Low	134 Å²	134	83.9 Å²	83.9	58%	0.583	42%	0.422	S	S	*	.	S	Bend	trans	-103.3	115.6	171.7	-70	-179	-179.9	173.7	0	109.8	Y64 M65 D69 Y70	Y64-K67 PolarHBondContact O-N 3.29Å; M65-K67 PolarHBondContact O-N 2.96Å; M65-K67 VanDerWaalsContact O-N 3.17Å; K67-D69 PolarHBondContact O-N 3.39Å; K67-Y70 VanDerWaalsContact O-CB 3.31Å; K67-Y70 WeakPolarHBondContact O-CB 3.06Å; K67-Y70 PolarHBondContact O-N 2.88Å; K67-Y70 VanDerWaalsContact O-N 3.15Å
68	N	52.1	Low	58.5	Low	167 Å²	167	83.9 Å²	83.9	89%	0.893	42%	0.422	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.9	-12.1	-173.4	-72.2	-16.1	0	0	0	116.1
69	D	50.5	Low	58.9	Low	168 Å²	168	86.8 Å²	86.8	90%	0.898	44%	0.437	S	S	*	.	T	Hydrogen-bonded Turn	trans	-109.5	29.8	177.7	-69.5	-36.1	0	0	0	112.9	K67 D71	K67-D69 PolarHBondContact O-N 3.39Å; D69-D71 PolarHBondContact O-N 2.98Å
70	Y	47.8	Very low	59.5	Low	53 Å²	53	87 Å²	87	21%	0.208	44%	0.44	C	S	.	.			trans	-81.2	106.7	-173.8	-156.5	-112.8	0	0	0	113.9	Y64 K67 C72 H75	Y64-Y70 VanDerWaalsContact CB-OH 3.24Å; Y64-Y70 WeakPolarHBondContact CB-OH 3.46Å; Y64-Y70 HydrophobicContact CD1-CD2 4.25Å; Y64-Y70 AromaticContact CD1-CE2 3.37Å; Y64-Y70 HydrophobicContact CD1-CE2 3.37Å; Y64-Y70 AromaticContact CD1-CZ 3.66Å; Y64-Y70 WeakPolarHBondContact CD1-OH 3.44Å; Y64-Y70 HydrophobicContact CE1-CE2 4.27Å; Y64-Y70 AromaticContact CG-CE2 3.91Å; Y64-Y70 HydrophobicContact CG-CE2 3.91Å; Y64-Y70 AromaticContact CG-CZ 3.74Å; K67-Y70 VanDerWaalsContact O-CB 3.31Å; K67-Y70 WeakPolarHBondContact O-CB 3.06Å; K67-Y70 PolarHBondContact O-N 2.88Å; K67-Y70 VanDerWaalsContact O-N 3.15Å; Y70-C72 PolarHBondContact O-N 3.23Å; Y70-H75 HydrophobicContact CE1-CB 3.68Å; Y70-H75 AromaticContact CE1-CD2 3.89Å; Y70-H75 AromaticContact CE1-CG 3.85Å; Y70-H75 AromaticContact CZ-CD2 3.82Å; Y70-H75 AromaticContact CZ-CG 3.56Å; Y70-H75 AromaticContact CZ-ND1 3.88Å; Y70-H75 WeakPolarHBondContact OH-CB 3.11Å; Y70-H75 PolarHBondContact OH-CD2 3.38Å; Y70-H75 PolarHBondContact OH-CE1 3.5Å; Y70-H75 PolarHBondContact OH-ND1 3.46Å; Y70-H75 PolarHBondContact OH-NE2 3.39Å
71	D	55.1	Low	60.2	Low	76 Å²	76	87 Å²	87	41%	0.406	44%	0.439	S	S	.	.			trans	-76.9	91.6	172.6	-168.2	-2.8	0	0	0	110.4	D69 S73 K74	D69-D71 PolarHBondContact O-N 2.98Å; D71-S73 VanDerWaalsContact CG-OG 3.23Å; D71-S73 PolarHBondContact O-N 3.01Å; D71-S73 WeakPolarHBondContact OD1-CB 3.38Å; D71-S73 PolarHBondContact OD1-N 3.01Å; D71-S73 PolarHBondContact OD1-OG 3.44Å; D71-S73 PolarHBondContact OD2-OG 3.4Å; D71-K74 PolarHBondContact O-N 3.25Å; D71-K74 WeakPolarHBondContact OD2-CE 3.34Å; D71-K74 IonicContact OD2-NZ 3.43Å
72	C	51.3	Low	61.5	Low	61 Å²	61	81.5 Å²	81.5	41%	0.412	42%	0.419	S	S	.	.	G	3₁₀ helix	trans	-55.3	-20.8	177.7	-70.1	0	0	0	0	113.2	Y70 K74	Y70-C72 PolarHBondContact O-N 3.23Å; C72-K74 VanDerWaalsContact C-N 3.26Å; C72-K74 PolarHBondContact O-N 3.21Å
73	S	58.4	Low	62.9	Low	96 Å²	96	73.6 Å²	73.6	67%	0.671	38%	0.382	S	S	*	.	G	3₁₀ helix	trans	-72	-18.1	178.2	74.5	0	0	0	0	113.9	D71	D71-S73 VanDerWaalsContact CG-OG 3.23Å; D71-S73 PolarHBondContact O-N 3.01Å; D71-S73 WeakPolarHBondContact OD1-CB 3.38Å; D71-S73 PolarHBondContact OD1-N 3.01Å; D71-S73 PolarHBondContact OD1-OG 3.44Å; D71-S73 PolarHBondContact OD2-OG 3.4Å
74	K	62.8	Low	64.2	Low	105 Å²	105	70.1 Å²	70.1	46%	0.457	37%	0.365	S	S	.	.	G	3₁₀ helix	trans	-107.2	11.3	-179.7	-65.2	179.2	-174	162	0	113.3	I55 T56 D71 C72	I55-K74 WeakPolarHBondContact CA-O 3.29Å; T56-K74 PolarHBondContact N-O 2.93Å; T56-K74 PolarHBondContact OG1-O 3.41Å; D71-K74 PolarHBondContact O-N 3.25Å; D71-K74 WeakPolarHBondContact OD2-CE 3.34Å; D71-K74 IonicContact OD2-NZ 3.43Å; C72-K74 VanDerWaalsContact C-N 3.26Å; C72-K74 PolarHBondContact O-N 3.21Å
75	H	66	Low	65.4	Low	20 Å²	20	67.4 Å²	67.4	9%	0.093	35%	0.354	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-124	130.4	-178.9	-168.3	67.1	0	0	0	112.7	T56 S58 Y64 Y70	T56-H75 WeakPolarHBondContact O-CA 3.39Å; T56-H75 PolarHBondContact O-ND1 3.06Å; T56-H75 VanDerWaalsContact O-ND1 3.11Å; T56-H75 PolarHBondContact OG1-ND1 3Å; S58-H75 WeakPolarHBondContact CB-CE1 3.3Å; S58-H75 WeakPolarHBondContact CB-NE2 3.27Å; S58-H75 PolarHBondContact OG-CE1 2.98Å; S58-H75 PolarHBondContact OG-NE2 3.43Å; Y64-H75 AromaticContact CD2-NE2 3.96Å; Y70-H75 HydrophobicContact CE1-CB 3.68Å; Y70-H75 AromaticContact CE1-CD2 3.89Å; Y70-H75 AromaticContact CE1-CG 3.85Å; Y70-H75 AromaticContact CZ-CD2 3.82Å; Y70-H75 AromaticContact CZ-CG 3.56Å; Y70-H75 AromaticContact CZ-ND1 3.88Å; Y70-H75 WeakPolarHBondContact OH-CB 3.11Å; Y70-H75 PolarHBondContact OH-CD2 3.38Å; Y70-H75 PolarHBondContact OH-CE1 3.5Å; Y70-H75 PolarHBondContact OH-ND1 3.46Å; Y70-H75 PolarHBondContact OH-NE2 3.39Å
76	I	69.7	Low	66.9	Low	9 Å²	9	63.2 Å²	63.2	5%	0.046	33%	0.334	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-123.9	120	177.1	-64.2	-174.4	0	0	0	109	Q48 F49 I55 T56 F57 S58 I82	Q48-I76 HydrophobicContact CB-CD1 4.13Å; F49-I76 HydrophobicContact CE1-CD1 4.18Å; I55-I76 HydrophobicContact CD1-CD1 3.9Å; I55-I76 HydrophobicContact CG2-CB 3.93Å; I55-I76 HydrophobicContact CG2-CD1 3.68Å; I55-I76 HydrophobicContact CG2-CG1 3.57Å; T56-I76 PolarHBondContact O-N 2.72Å; F57-I76 WeakPolarHBondContact CA-O 3.38Å; F57-I76 HydrophobicContact CD1-CB 4.09Å; F57-I76 HydrophobicContact CD1-CG2 4.23Å; F57-I76 HydrophobicContact CE1-CB 3.95Å; F57-I76 HydrophobicContact CE1-CD1 4.38Å; F57-I76 HydrophobicContact CE1-CG2 4.04Å; S58-I76 PolarHBondContact N-O 2.85Å; I76-I82 HydrophobicContact CG2-CD1 3.42Å; I76-I82 VanDerWaalsContact CG2-CD1 3.42Å; I76-I82 HydrophobicContact CG2-CG1 4.14Å; I76-I82 HydrophobicContact CG2-CG2 3.94Å
77	T	75.5	Confident	68.2	Low	39 Å²	39	57.7 Å²	57.7	24%	0.239	30%	0.304	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-77.4	121.4	169.1	-58.4	0	0	0	0	109.3	S58 Y61 N79 I82	S58-T77 CarbonylContact O-C 3.22Å; S58-T77 WeakPolarHBondContact O-CA 3.27Å; Y61-T77 WeakPolarHBondContact CD2-OG1 3.42Å; T77-N79 PolarHBondContact O-N 2.84Å; T77-I82 WeakPolarHBondContact O-CD1 3.35Å
78	I	77.6	Confident	69.1	Low	4 Å²	4	54 Å²	54	2%	0.021	29%	0.289	C	S	.	.			trans	-70.2	120.9	-178.1	-66.7	167.4	0	0	0	109.6	F57 S58 M59 L83 F119 C122 I126 F136	F57-I78 HydrophobicContact CB-CD1 3.76Å; F57-I78 HydrophobicContact CB-CG1 4.15Å; F57-I78 HydrophobicContact CD1-CD1 4.03Å; F57-I78 HydrophobicContact CD1-CG1 3.76Å; F57-I78 HydrophobicContact CG-CD1 4.23Å; F57-I78 HydrophobicContact CG-CG1 4.39Å; S58-I78 PolarHBondContact O-N 2.98Å; M59-I78 HydrophobicContact SD-CB 4.37Å; I78-L83 HydrophobicContact CG2-CD1 3.93Å; I78-L83 HydrophobicContact CG2-CD2 3.82Å; I78-L83 HydrophobicContact CG2-CG 3.73Å; I78-F119 HydrophobicContact CD1-CD2 3.95Å; I78-F119 HydrophobicContact CD1-CE2 4.33Å; I78-C122 HydrophobicContact CD1-CB 3.29Å; I78-I126 HydrophobicContact CB-CD1 4.44Å; I78-I126 HydrophobicContact CG2-CD1 3.64Å; I78-F136 HydrophobicContact CG2-CE2 4.26Å; I78-F136 HydrophobicContact CG2-CZ 4.29Å
79	N	79.9	Confident	70.2	Confident	68 Å²	68	46 Å²	46	36%	0.364	25%	0.246	S	C	.	.			trans	-129.4	178.6	168.8	68.6	20.6	0	0	0	110.1	T77 D81 I82 L83	T77-N79 PolarHBondContact O-N 2.84Å; N79-D81 VanDerWaalsContact C-N 3.3Å; N79-D81 PolarHBondContact O-N 3.4Å; N79-D81 PolarHBondContact OD1-N 3.43Å; N79-D81 VanDerWaalsContact OD1-N 3.09Å; N79-I82 PolarHBondContact O-N 2.96Å; N79-I82 WeakPolarHBondContact OD1-CG1 3.18Å; N79-I82 PolarHBondContact OD1-N 3.27Å; N79-L83 WeakPolarHBondContact O-CG 3.36Å; N79-L83 PolarHBondContact O-N 2.92Å; N79-L83 VanDerWaalsContact O-N 3.14Å
80	T	75.9	Confident	71.4	Confident	33 Å²	33	38.1 Å²	38.1	20%	0.202	20%	0.204	C	C	.	.	H	α-helix	trans	-57.7	-39.4	-179.5	48.9	0	0	0	0	113	L83 K84 Y135 F136	T80-L83 PolarHBondContact O-N 3.3Å; T80-K84 WeakPolarHBondContact O-CG 3.25Å; T80-K84 PolarHBondContact O-N 2.85Å; T80-Y135 HydrophobicContact CG2-CD1 4.07Å; T80-Y135 HydrophobicContact CG2-CE1 4.44Å; T80-F136 HydrophobicContact CG2-CB 4.04Å; T80-F136 HydrophobicContact CG2-CD2 3.71Å; T80-F136 HydrophobicContact CG2-CE2 4.45Å; T80-F136 HydrophobicContact CG2-CG 4.08Å
81	D	75.9	Confident	72.7	Confident	77 Å²	77	36.9 Å²	36.9	41%	0.412	20%	0.201	S	C	.	.	H	α-helix	trans	-74	-38.8	-175.4	-62.6	-30.5	0	0	0	112.1	N79 L83 K84 C85	N79-D81 VanDerWaalsContact C-N 3.3Å; N79-D81 PolarHBondContact O-N 3.4Å; N79-D81 PolarHBondContact OD1-N 3.43Å; N79-D81 VanDerWaalsContact OD1-N 3.09Å; D81-L83 VanDerWaalsContact C-N 3.32Å; D81-L83 PolarHBondContact O-N 3.35Å; D81-K84 WeakPolarHBondContact O-CB 3.16Å; D81-K84 PolarHBondContact O-N 3.33Å; D81-K84 IonicContact OD1-NZ 3.97Å; D81-K84 PolarHBondContact OD1-NZ 3.42Å; D81-C85 PolarHBondContact O-N 3.04Å; D81-C85 PolarHBondContact O-SG 2.85Å; D81-C85 VanDerWaalsContact O-SG 3.35Å
82	I	80.6	Confident	73.4	Confident	12 Å²	12	33.7 Å²	33.7	6%	0.062	18%	0.184	C	C	.	.	H	α-helix	trans	-61.9	-42.6	173	-72.4	158	0	0	0	110.5	L45 F49 I76 T77 N79 C85 I86	L45-I82 HydrophobicContact CD2-CG1 4.09Å; F49-I82 HydrophobicContact CZ-CG2 4.44Å; I76-I82 HydrophobicContact CG2-CD1 3.42Å; I76-I82 VanDerWaalsContact CG2-CD1 3.42Å; I76-I82 HydrophobicContact CG2-CG1 4.14Å; I76-I82 HydrophobicContact CG2-CG2 3.94Å; T77-I82 WeakPolarHBondContact O-CD1 3.35Å; N79-I82 PolarHBondContact O-N 2.96Å; N79-I82 WeakPolarHBondContact OD1-CG1 3.18Å; N79-I82 PolarHBondContact OD1-N 3.27Å; I82-C85 PolarHBondContact O-N 3.41Å; I82-I86 HydrophobicContact CG2-CD1 3.8Å; I82-I86 HydrophobicContact CG2-CG1 4.43Å; I82-I86 WeakPolarHBondContact O-CB 3.4Å; I82-I86 VanDerWaalsContact O-CG1 3.29Å; I82-I86 WeakPolarHBondContact O-CG1 3.13Å; I82-I86 PolarHBondContact O-N 3.11Å
83	L	82.6	Confident	74.2	Confident	0 Å²	0	32 Å²	32	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-64.5	-38.5	175.7	-70.2	-178.2	0	0	0	112.4	I78 N79 T80 D81 N87 F119 L123 I126 F136 I139 A140 V143	I78-L83 HydrophobicContact CG2-CD1 3.93Å; I78-L83 HydrophobicContact CG2-CD2 3.82Å; I78-L83 HydrophobicContact CG2-CG 3.73Å; N79-L83 WeakPolarHBondContact O-CG 3.36Å; N79-L83 PolarHBondContact O-N 2.92Å; N79-L83 VanDerWaalsContact O-N 3.14Å; T80-L83 PolarHBondContact O-N 3.3Å; D81-L83 VanDerWaalsContact C-N 3.32Å; D81-L83 PolarHBondContact O-N 3.35Å; L83-N87 VanDerWaalsContact O-CB 3.31Å; L83-N87 WeakPolarHBondContact O-CB 3.23Å; L83-N87 PolarHBondContact O-N 3.04Å; L83-F119 HydrophobicContact CD2-CE2 4.32Å; L83-L123 HydrophobicContact CD1-CD2 4.42Å; L83-L123 HydrophobicContact CD2-CD2 3.7Å; L83-I126 HydrophobicContact CD1-CD1 4.42Å; L83-F136 HydrophobicContact CD1-CD2 4.01Å; L83-F136 HydrophobicContact CD1-CE2 3.61Å; L83-I139 HydrophobicContact CB-CD1 4.23Å; L83-I139 HydrophobicContact CB-CG1 4.15Å; L83-I139 HydrophobicContact CB-CG2 4.14Å; L83-I139 HydrophobicContact CD1-CG2 3.83Å; L83-A140 HydrophobicContact CD1-CB 3.96Å; L83-V143 HydrophobicContact CB-CG2 4.14Å; L83-V143 HydrophobicContact CD2-CG2 4.28Å
84	K	79	Confident	74.5	Confident	62 Å²	62	30.9 Å²	30.9	27%	0.27	16%	0.158	S	C	.	.	H	α-helix	trans	-58.9	-50.2	171.4	-71.1	172.6	-173	160.4	0	111.2	T80 D81 I86 N87 Q88 Y135 I139	T80-K84 WeakPolarHBondContact O-CG 3.25Å; T80-K84 PolarHBondContact O-N 2.85Å; D81-K84 WeakPolarHBondContact O-CB 3.16Å; D81-K84 PolarHBondContact O-N 3.33Å; D81-K84 IonicContact OD1-NZ 3.97Å; D81-K84 PolarHBondContact OD1-NZ 3.42Å; K84-I86 PolarHBondContact O-N 3.06Å; K84-N87 PolarHBondContact O-N 3.41Å; K84-Q88 WeakPolarHBondContact O-CG 3.01Å; K84-Q88 PolarHBondContact O-N 3.38Å; K84-Y135 WeakPolarHBondContact CE-OH 3.26Å; K84-I139 HydrophobicContact CB-CD1 4.1Å; K84-I139 HydrophobicContact CD-CD1 4.36Å; K84-I139 HydrophobicContact CG-CD1 3.19Å
85	C	74.7	Confident	74.4	Confident	2 Å²	2	28.4 Å²	28.4	1%	0.014	15%	0.148	C	C	.	.	H	α-helix	trans	-60.7	-45.8	-179.7	-70.2	0	0	0	0	111.7	F49 D81 I82 N87 Q88 C89	F49-C85 HydrophobicContact CE2-CB 3.99Å; F49-C85 HydrophobicContact CZ-CB 4.35Å; D81-C85 PolarHBondContact O-N 3.04Å; D81-C85 PolarHBondContact O-SG 2.85Å; D81-C85 VanDerWaalsContact O-SG 3.35Å; I82-C85 PolarHBondContact O-N 3.41Å; C85-N87 VanDerWaalsContact C-N 3.33Å; C85-N87 PolarHBondContact O-N 3.13Å; C85-Q88 PolarHBondContact O-N 2.91Å; C85-C89 WeakPolarHBondContact O-CB 3.11Å; C85-C89 PolarHBondContact O-N 3.4Å; C85-C89 PolarHBondContact O-SG 3.37Å
86	I	81.2	Confident	73.8	Confident	1 Å²	1	31.7 Å²	31.7	1%	0.005	17%	0.173	C	C	.	.	H	α-helix	trans	-58.8	-47.6	176.3	-70.9	169.6	0	0	0	110.2	F49 F52 F57 I82 K84 Q88 C89 L90 L113 F119 V143	F49-I86 HydrophobicContact CE1-CD1 4.35Å; F49-I86 HydrophobicContact CE1-CG1 3.94Å; F49-I86 HydrophobicContact CZ-CG1 4Å; F52-I86 HydrophobicContact CE2-CD1 4.09Å; F52-I86 HydrophobicContact CE2-CG1 4.13Å; F52-I86 HydrophobicContact CZ-CD1 4.03Å; F57-I86 HydrophobicContact CE1-CD1 4.46Å; I82-I86 HydrophobicContact CG2-CD1 3.8Å; I82-I86 HydrophobicContact CG2-CG1 4.43Å; I82-I86 WeakPolarHBondContact O-CB 3.4Å; I82-I86 VanDerWaalsContact O-CG1 3.29Å; I82-I86 WeakPolarHBondContact O-CG1 3.13Å; I82-I86 PolarHBondContact O-N 3.11Å; K84-I86 PolarHBondContact O-N 3.06Å; I86-Q88 VanDerWaalsContact C-N 3.35Å; I86-Q88 PolarHBondContact O-N 3.42Å; I86-C89 PolarHBondContact O-N 2.91Å; I86-L90 WeakPolarHBondContact O-CB 3.29Å; I86-L90 PolarHBondContact O-N 3.46Å; I86-L113 HydrophobicContact CG2-CD1 3.63Å; I86-L113 HydrophobicContact CG2-CD2 3.95Å; I86-L113 HydrophobicContact CG2-CG 4.48Å; I86-F119 HydrophobicContact CD1-CE2 3.71Å; I86-F119 HydrophobicContact CD1-CZ 4.12Å; I86-F119 HydrophobicContact CG2-CZ 4.34Å; I86-V143 HydrophobicContact CG2-CG1 4.18Å
87	N	80.7	Confident	72.9	Confident	24 Å²	24	36.6 Å²	36.6	13%	0.128	19%	0.194	C	C	.	.	H	α-helix	trans	-61.8	-41.9	-179.8	-166.9	46	0	0	0	112.3	L83 K84 C85 L90 L91 V143 N146	L83-N87 VanDerWaalsContact O-CB 3.31Å; L83-N87 WeakPolarHBondContact O-CB 3.23Å; L83-N87 PolarHBondContact O-N 3.04Å; K84-N87 PolarHBondContact O-N 3.41Å; C85-N87 VanDerWaalsContact C-N 3.33Å; C85-N87 PolarHBondContact O-N 3.13Å; N87-L90 PolarHBondContact O-N 3.33Å; N87-L91 VanDerWaalsContact O-CG 3.27Å; N87-L91 WeakPolarHBondContact O-CG 3.38Å; N87-L91 PolarHBondContact O-N 3.49Å; N87-L91 VanDerWaalsContact O-N 3.07Å; N87-V143 HydrophobicContact CB-CG2 3.92Å; N87-N146 PolarHBondContact OD1-ND2 3.42Å
88	Q	74.3	Confident	71.7	Confident	56 Å²	56	36.5 Å²	36.5	26%	0.262	19%	0.19	S	C	.	.	H	α-helix	trans	-64.6	-49.1	176.4	-73.1	179.3	-8.8	0	0	111.9	Y46 K84 C85 I86 L90 L91 I92	Y46-Q88 PolarHBondContact OH-OE1 3.03Å; K84-Q88 WeakPolarHBondContact O-CG 3.01Å; K84-Q88 PolarHBondContact O-N 3.38Å; C85-Q88 PolarHBondContact O-N 2.91Å; I86-Q88 VanDerWaalsContact C-N 3.35Å; I86-Q88 PolarHBondContact O-N 3.42Å; Q88-L90 VanDerWaalsContact C-N 3.26Å; Q88-L90 PolarHBondContact O-N 3.25Å; Q88-L91 PolarHBondContact O-N 2.9Å; Q88-I92 WeakPolarHBondContact O-CB 3.29Å; Q88-I92 WeakPolarHBondContact O-CD1 3.38Å; Q88-I92 WeakPolarHBondContact O-CG1 3.49Å; Q88-I92 PolarHBondContact O-N 2.86Å
89	C	74.6	Confident	70.4	Confident	0 Å²	0	39.4 Å²	39.4	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-55.4	-43.3	175.4	-77.8	0	0	0	0	112	Y46 C85 I86 I92 T93 V108	Y46-C89 WeakPolarHBondContact CE1-SG 3.14Å; C85-C89 WeakPolarHBondContact O-CB 3.11Å; C85-C89 PolarHBondContact O-N 3.4Å; C85-C89 PolarHBondContact O-SG 3.37Å; I86-C89 PolarHBondContact O-N 2.91Å; C89-I92 PolarHBondContact O-N 3.34Å; C89-T93 WeakPolarHBondContact O-CB 3.44Å; C89-T93 PolarHBondContact O-N 3.46Å; C89-T93 VanDerWaalsContact O-N 3.09Å; C89-T93 PolarHBondContact O-OG1 3.38Å; C89-V108 HydrophobicContact CB-CB 3.87Å; C89-V108 HydrophobicContact CB-CG2 3.62Å
90	L	76.6	Confident	68.9	Low	2 Å²	2	43.9 Å²	43.9	1%	0.01	23%	0.227	C	C	.	.	H	α-helix	trans	-62.2	-46	-179.4	-177.2	66.5	0	0	0	111.3	I86 N87 Q88 T93 W110 L113 N146 I147 L150	I86-L90 WeakPolarHBondContact O-CB 3.29Å; I86-L90 PolarHBondContact O-N 3.46Å; N87-L90 PolarHBondContact O-N 3.33Å; Q88-L90 VanDerWaalsContact C-N 3.26Å; Q88-L90 PolarHBondContact O-N 3.25Å; L90-T93 PolarHBondContact O-N 2.96Å; L90-W110 HydrophobicContact CD1-CB 4.04Å; L90-L113 HydrophobicContact CD1-CD1 4.05Å; L90-L113 HydrophobicContact CD2-CD1 4.3Å; L90-N146 HydrophobicContact CD2-CB 3.9Å; L90-I147 HydrophobicContact CD2-CG1 3.78Å; L90-L150 HydrophobicContact CD1-CD1 3.51Å; L90-L150 HydrophobicContact CD2-CD1 3.77Å; L90-L150 HydrophobicContact CG-CD1 3.29Å
91	L	73.6	Confident	67.7	Low	27 Å²	27	48.7 Å²	48.7	14%	0.141	25%	0.25	C	S	.	.	H	α-helix	trans	-69.2	-35.4	178.9	-68	171.2	0	0	0	113.3	Y15 N87 Q88 T93 Q95	Y15-L91 WeakPolarHBondContact OH-CD1 3.05Å; N87-L91 VanDerWaalsContact O-CG 3.27Å; N87-L91 WeakPolarHBondContact O-CG 3.38Å; N87-L91 PolarHBondContact O-N 3.49Å; N87-L91 VanDerWaalsContact O-N 3.07Å; Q88-L91 PolarHBondContact O-N 2.9Å; L91-T93 VanDerWaalsContact C-N 3.34Å; L91-Q95 PolarHBondContact O-N 3.48Å
92	I	70.2	Confident	66.5	Low	10 Å²	10	46.2 Å²	46.2	5%	0.051	24%	0.239	C	C	.	.	H	α-helix	trans	-69.4	-34.8	178.7	-69.6	163.2	0	0	0	111.8	Q88 C89 D94 Q95 Q99 S102 I104	Q88-I92 WeakPolarHBondContact O-CB 3.29Å; Q88-I92 WeakPolarHBondContact O-CD1 3.38Å; Q88-I92 WeakPolarHBondContact O-CG1 3.49Å; Q88-I92 PolarHBondContact O-N 2.86Å; C89-I92 PolarHBondContact O-N 3.34Å; I92-D94 VanDerWaalsContact C-N 3.28Å; I92-D94 PolarHBondContact O-N 2.9Å; I92-Q95 PolarHBondContact O-N 3.3Å; I92-Q99 HydrophobicContact CG2-CB 4.49Å; I92-Q99 HydrophobicContact CG2-CG 3.58Å; I92-S102 VanDerWaalsContact CD1-OG 3.3Å; I92-S102 WeakPolarHBondContact CD1-OG 3.26Å; I92-I104 HydrophobicContact CD1-CB 3.83Å; I92-I104 HydrophobicContact CD1-CD1 3.57Å; I92-I104 HydrophobicContact CD1-CG1 4.24Å; I92-I104 HydrophobicContact CD1-CG2 4.1Å
93	T	68.7	Low	65.1	Low	25 Å²	25	48.7 Å²	48.7	15%	0.153	27%	0.267	C	S	.	.	H	α-helix	trans	-64.3	-34.9	-178.2	-58.4	0	0	0	0	112	C89 L90 L91 R107 V108 Y109	C89-T93 WeakPolarHBondContact O-CB 3.44Å; C89-T93 PolarHBondContact O-N 3.46Å; C89-T93 VanDerWaalsContact O-N 3.09Å; C89-T93 PolarHBondContact O-OG1 3.38Å; L90-T93 PolarHBondContact O-N 2.96Å; L91-T93 VanDerWaalsContact C-N 3.34Å; T93-R107 HydrophobicContact CG2-CB 3.96Å; T93-R107 HydrophobicContact CG2-CG 4.27Å; T93-R107 WeakPolarHBondContact OG1-CA 3.18Å; T93-V108 WeakPolarHBondContact CB-O 3.28Å; T93-V108 PolarHBondContact OG1-N 2.99Å; T93-V108 PolarHBondContact OG1-O 3.17Å; T93-V108 VanDerWaalsContact OG1-O 3.14Å; T93-Y109 HydrophobicContact CG2-CD1 3.51Å; T93-Y109 HydrophobicContact CG2-CD2 4.49Å; T93-Y109 HydrophobicContact CG2-CE1 3.43Å; T93-Y109 VanDerWaalsContact CG2-CE1 3.43Å; T93-Y109 HydrophobicContact CG2-CE2 4.43Å; T93-Y109 HydrophobicContact CG2-CG 4.06Å
94	D	64.2	Low	63.8	Low	73 Å²	73	49.6 Å²	49.6	39%	0.39	27%	0.272	S	S	.	.	H	α-helix	trans	-86.2	-29.1	-178.6	-162.6	49.5	0	0	0	113.1	I92 L150	I92-D94 VanDerWaalsContact C-N 3.28Å; I92-D94 PolarHBondContact O-N 2.9Å; D94-L150 HydrophobicContact CB-CD2 3.69Å; D94-L150 VanDerWaalsContact OD2-CD2 3.23Å; D94-L150 WeakPolarHBondContact OD2-CD2 3.36Å
95	Q	60.1	Low	62.8	Low	52 Å²	52	56.1 Å²	56.1	24%	0.243	30%	0.3	C	S	.	.			trans	-118.5	111.7	-177.1	-57	-167	12.5	0	0	113.5	L91 I92 K97 Y98	L91-Q95 PolarHBondContact O-N 3.48Å; I92-Q95 PolarHBondContact O-N 3.3Å; Q95-K97 PolarHBondContact O-N 3.45Å; Q95-Y98 HydrophobicContact CB-CD2 3.58Å; Q95-Y98 HydrophobicContact CB-CE2 3.89Å; Q95-Y98 HydrophobicContact CB-CG 4.47Å; Q95-Y98 HydrophobicContact CG-CD2 4.15Å; Q95-Y98 HydrophobicContact CG-CE2 4Å; Q95-Y98 PolarHBondContact O-N 3.4Å; Q95-Y98 PolarHBondContact OE1-OH 3.1Å
96	S	54.1	Low	62.3	Low	90 Å²	90	56.9 Å²	56.9	63%	0.629	31%	0.305	S	S	*	.	H	α-helix	trans	-54.9	-28.2	173.6	59.1	0	0	0	0	113.6	Y98 Q99	S96-Y98 VanDerWaalsContact C-N 3.3Å; S96-Y98 PolarHBondContact O-N 3.39Å; S96-Q99 PolarHBondContact O-N 2.95Å
97	K	50.8	Low	61.8	Low	112 Å²	112	62.5 Å²	62.5	49%	0.487	33%	0.327	S	S	.	.	H	α-helix	trans	-63.6	-31.1	178.2	-68.2	176.8	-174.7	161.3	0	113	Q95	Q95-K97 PolarHBondContact O-N 3.45Å
98	Y	50	Low	61.5	Low	37 Å²	37	61.5 Å²	61.5	15%	0.145	32%	0.321	C	S	.	.	H	α-helix	trans	-83.8	-19.7	179.6	-63.1	-52.4	0	0	0	113.7	Y15 L19 Q95 S96 L100 L101 S102	Y15-Y98 VanDerWaalsContact CD1-OH 3.27Å; Y15-Y98 WeakPolarHBondContact CD1-OH 3.26Å; Y15-Y98 AromaticContact CE1-CZ 3.91Å; Y15-Y98 WeakPolarHBondContact CE1-OH 3.31Å; L19-Y98 HydrophobicContact CD2-CE1 4.43Å; Q95-Y98 HydrophobicContact CB-CD2 3.58Å; Q95-Y98 HydrophobicContact CB-CE2 3.89Å; Q95-Y98 HydrophobicContact CB-CG 4.47Å; Q95-Y98 HydrophobicContact CG-CD2 4.15Å; Q95-Y98 HydrophobicContact CG-CE2 4Å; Q95-Y98 PolarHBondContact O-N 3.4Å; Q95-Y98 PolarHBondContact OE1-OH 3.1Å; S96-Y98 VanDerWaalsContact C-N 3.3Å; S96-Y98 PolarHBondContact O-N 3.39Å; Y98-L100 VanDerWaalsContact C-N 3.27Å; Y98-L100 PolarHBondContact O-N 2.89Å; Y98-L101 PolarHBondContact O-N 2.99Å; Y98-S102 PolarHBondContact O-N 3.25Å; Y98-S102 PolarHBondContact O-OG 3.33Å
99	Q	50.4	Low	61.9	Low	65 Å²	65	61.3 Å²	61.3	30%	0.304	32%	0.318	S	S	.	.	H	α-helix	trans	-60.9	-37.3	175.3	-73.8	-165	-50.1	0	0	111.9	I92 S96 R107	I92-Q99 HydrophobicContact CG2-CB 4.49Å; I92-Q99 HydrophobicContact CG2-CG 3.58Å; S96-Q99 PolarHBondContact O-N 2.95Å; Q99-R107 VanDerWaalsContact NE2-NE 3.17Å
100	L	49.3	Very low	62.4	Low	162 Å²	162	61.7 Å²	61.7	85%	0.848	32%	0.32	S	S	*	.	H	α-helix	trans	-71	-33.3	179	-85.1	155.1	0	0	0	113.3	Y98	Y98-L100 VanDerWaalsContact C-N 3.27Å; Y98-L100 PolarHBondContact O-N 2.89Å
101	L	49.6	Very low	62.9	Low	134 Å²	134	63.5 Å²	63.5	70%	0.702	33%	0.327	S	S	*	.	H	α-helix	trans	-85.5	-28.4	-174	-72	168.2	0	0	0	113.5	Y98	Y98-L101 PolarHBondContact O-N 2.99Å
102	S	51.9	Low	63.4	Low	25 Å²	25	64.3 Å²	64.3	18%	0.175	33%	0.33	C	S	.	.	H	α-helix	trans	-98.8	-20.9	-169.8	57.3	0	0	0	0	114.7	I92 Y98 I104	I92-S102 VanDerWaalsContact CD1-OG 3.3Å; I92-S102 WeakPolarHBondContact CD1-OG 3.26Å; Y98-S102 PolarHBondContact O-N 3.25Å; Y98-S102 PolarHBondContact O-OG 3.33Å; S102-I104 PolarHBondContact O-N 3.14Å
103	G	51.5	Low	64.2	Low	63 Å²	63	63.8 Å²	63.8	65%	0.649	33%	0.327	S	S	*	.			trans	66.9	-4	-171.6	0	0	0	0	0	114.7	K105	G103-K105 PolarHBondContact O-N 2.75Å
104	I	55.3	Low	65.2	Low	20 Å²	20	62.6 Å²	62.6	10%	0.103	32%	0.32	C	S	.	.			trans	-74.7	121.8	-178.9	-63.1	165.3	0	0	0	109.3	Y46 I92 S102 C106	Y46-I104 HydrophobicContact CD1-CG2 4.06Å; Y46-I104 HydrophobicContact CE1-CD1 4.02Å; Y46-I104 HydrophobicContact CE1-CG1 4.22Å; Y46-I104 HydrophobicContact CE1-CG2 3.8Å; Y46-I104 HydrophobicContact CE2-CG1 4.44Å; Y46-I104 WeakPolarHBondContact OH-CD1 3.25Å; I92-I104 HydrophobicContact CD1-CB 3.83Å; I92-I104 HydrophobicContact CD1-CD1 3.57Å; I92-I104 HydrophobicContact CD1-CG1 4.24Å; I92-I104 HydrophobicContact CD1-CG2 4.1Å; S102-I104 PolarHBondContact O-N 3.14Å; I104-C106 HydrophobicContact CG2-CB 4.27Å
105	K	57.1	Low	66.3	Low	198 Å²	198	63.5 Å²	63.5	86%	0.861	32%	0.318	S	S	*	.			trans	-91.6	-13.4	178.2	-66.9	-177.7	-179.3	175.8	0	113.8	G103	G103-K105 PolarHBondContact O-N 2.75Å
106	C	64.6	Low	67.6	Low	18 Å²	18	62.1 Å²	62.1	12%	0.122	31%	0.314	C	S	.	.			trans	-77.4	132.5	-175.7	-162.8	0	0	0	0	110.8	Y46 I104	Y46-C106 HydrophobicContact CD1-CB 4.28Å; I104-C106 HydrophobicContact CG2-CB 4.27Å
107	R	69.8	Low	69.3	Low	120 Å²	120	62.2 Å²	62.2	45%	0.453	30%	0.304	S	S	.	.			trans	-112.2	125.6	174.7	-72.7	-175.7	178.1	172.3	1	108.8	T93 Q99	T93-R107 HydrophobicContact CG2-CB 3.96Å; T93-R107 HydrophobicContact CG2-CG 4.27Å; T93-R107 WeakPolarHBondContact OG1-CA 3.18Å; Q99-R107 VanDerWaalsContact NE2-NE 3.17Å
108	V	75	Confident	71	Confident	2 Å²	2	60.7 Å²	60.7	1%	0.012	30%	0.299	C	S	.	.			trans	-121.3	119.6	174.8	177.1	0	0	0	0	107.6	C89 T93 L113	C89-V108 HydrophobicContact CB-CB 3.87Å; C89-V108 HydrophobicContact CB-CG2 3.62Å; T93-V108 WeakPolarHBondContact CB-O 3.28Å; T93-V108 PolarHBondContact OG1-N 2.99Å; T93-V108 PolarHBondContact OG1-O 3.17Å; T93-V108 VanDerWaalsContact OG1-O 3.14Å; V108-L113 HydrophobicContact CG1-CD1 3.97Å; V108-L113 HydrophobicContact CG1-CD2 3.62Å; V108-L113 HydrophobicContact CG1-CG 3.69Å
109	Y	81.6	Confident	72.9	Confident	53 Å²	53	58.9 Å²	58.9	21%	0.208	29%	0.292	C	S	.	.			trans	-89.6	145.8	176.9	-60.4	-85.5	0	0	0	110.6	T93 Y111 Q112 L113 Y157	T93-Y109 HydrophobicContact CG2-CD1 3.51Å; T93-Y109 HydrophobicContact CG2-CD2 4.49Å; T93-Y109 HydrophobicContact CG2-CE1 3.43Å; T93-Y109 VanDerWaalsContact CG2-CE1 3.43Å; T93-Y109 HydrophobicContact CG2-CE2 4.43Å; T93-Y109 HydrophobicContact CG2-CG 4.06Å; Y109-Y111 HydrophobicContact CD1-CE1 4.06Å; Y109-Y111 HydrophobicContact CD2-CE1 4.16Å; Y109-Y111 HydrophobicContact CG-CD1 4.36Å; Y109-Y111 AromaticContact CG-CE1 3.56Å; Y109-Y111 HydrophobicContact CG-CE1 3.56Å; Y109-Y111 AromaticContact CG-CZ 3.98Å; Y109-Y111 PolarHBondContact O-N 2.63Å; Y109-Y111 VanDerWaalsContact O-N 3.13Å; Y109-Q112 WeakPolarHBondContact O-CB 3.32Å; Y109-Q112 PolarHBondContact O-N 2.66Å; Y109-L113 PolarHBondContact O-N 3.37Å; Y109-Y157 HydrophobicContact CE1-CE2 4.2Å
110	W	86.5	Confident	74.9	Confident	8 Å²	8	55.8 Å²	55.8	3%	0.03	28%	0.277	C	S	.	.	H	α-helix	trans	-52.8	-37.8	179.4	72.3	-94	0	0	0	112.5	L90 Q112 L113 A114 I147 L150 A151 C163 A166 L170 Y208	L90-W110 HydrophobicContact CD1-CB 4.04Å; W110-Q112 VanDerWaalsContact C-N 3.34Å; W110-Q112 PolarHBondContact O-N 3.27Å; W110-L113 PolarHBondContact O-N 3.37Å; W110-A114 HydrophobicContact CE3-CB 4.17Å; W110-A114 HydrophobicContact CZ3-CB 4.29Å; W110-A114 WeakPolarHBondContact O-CB 3.41Å; W110-A114 PolarHBondContact O-N 3.49Å; W110-I147 HydrophobicContact CB-CG2 4.4Å; W110-L150 HydrophobicContact CB-CB 4.17Å; W110-L150 HydrophobicContact CG-CB 4.45Å; W110-A151 HydrophobicContact CD2-CB 3.71Å; W110-A151 HydrophobicContact CE3-CB 3.59Å; W110-A151 HydrophobicContact CG-CB 4.4Å; W110-A151 HydrophobicContact CH2-CB 4.07Å; W110-A151 HydrophobicContact CZ2-CB 4.19Å; W110-A151 HydrophobicContact CZ3-CB 3.77Å; W110-C163 HydrophobicContact CH2-CB 4.19Å; W110-C163 WeakPolarHBondContact CH2-O 3.19Å; W110-C163 HydrophobicContact CZ2-CB 3.96Å; W110-A166 HydrophobicContact CH2-CB 4.11Å; W110-A166 HydrophobicContact CZ3-CB 3.74Å; W110-L170 HydrophobicContact CE3-CD1 4.06Å; W110-L170 HydrophobicContact CZ3-CD1 3.86Å; W110-Y208 HydrophobicContact CH2-CE2 4.43Å; W110-Y208 HydrophobicContact CZ2-CE2 4.16Å; W110-Y208 AromaticContact CZ2-CZ 3.92Å; W110-Y208 WeakPolarHBondContact CZ2-OH 3.37Å
111	Y	86.4	Confident	76.9	Confident	40 Å²	40	53.7 Å²	53.7	16%	0.157	26%	0.261	C	S	.	.	H	α-helix	trans	-69.9	-31	-177.1	65.7	-96.3	0	0	0	112.1	Y109 A114 R115 D162 A166	Y109-Y111 HydrophobicContact CD1-CE1 4.06Å; Y109-Y111 HydrophobicContact CD2-CE1 4.16Å; Y109-Y111 HydrophobicContact CG-CD1 4.36Å; Y109-Y111 AromaticContact CG-CE1 3.56Å; Y109-Y111 HydrophobicContact CG-CE1 3.56Å; Y109-Y111 AromaticContact CG-CZ 3.98Å; Y109-Y111 PolarHBondContact O-N 2.63Å; Y109-Y111 VanDerWaalsContact O-N 3.13Å; Y111-A114 PolarHBondContact O-N 2.86Å; Y111-R115 WeakPolarHBondContact O-CB 3.33Å; Y111-R115 VanDerWaalsContact O-CG 3.25Å; Y111-R115 WeakPolarHBondContact O-CG 3.35Å; Y111-R115 PolarHBondContact O-N 3.44Å; Y111-D162 HydrophobicContact CD2-CB 4.16Å; Y111-D162 HydrophobicContact CE2-CB 4.45Å; Y111-A166 WeakPolarHBondContact O-CB 3.44Å
112	Q	85.2	Confident	78.8	Confident	43 Å²	43	47.8 Å²	47.8	20%	0.201	23%	0.231	C	C	.	.	H	α-helix	trans	-65.7	-41.5	176.2	-64.7	174.6	-48.4	0	0	110.8	Y109 W110	Y109-Q112 WeakPolarHBondContact O-CB 3.32Å; Y109-Q112 PolarHBondContact O-N 2.66Å; W110-Q112 VanDerWaalsContact C-N 3.34Å; W110-Q112 PolarHBondContact O-N 3.27Å
113	L	86.8	Confident	80.7	Confident	0 Å²	0	46.6 Å²	46.6	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-64.7	-49.5	174.5	-59.2	179.5	0	0	0	111	F52 I86 L90 V108 Y109 W110 R115 S116 F119 I147	F52-L113 HydrophobicContact CD1-CD2 3.78Å; F52-L113 HydrophobicContact CD2-CD2 3.95Å; F52-L113 HydrophobicContact CE1-CD2 3.2Å; F52-L113 HydrophobicContact CE1-CG 4.42Å; F52-L113 HydrophobicContact CE2-CD2 3.39Å; F52-L113 HydrophobicContact CG-CD2 4.14Å; F52-L113 HydrophobicContact CZ-CD2 2.97Å; F52-L113 HydrophobicContact CZ-CG 4.43Å; I86-L113 HydrophobicContact CG2-CD1 3.63Å; I86-L113 HydrophobicContact CG2-CD2 3.95Å; I86-L113 HydrophobicContact CG2-CG 4.48Å; L90-L113 HydrophobicContact CD1-CD1 4.05Å; L90-L113 HydrophobicContact CD2-CD1 4.3Å; V108-L113 HydrophobicContact CG1-CD1 3.97Å; V108-L113 HydrophobicContact CG1-CD2 3.62Å; V108-L113 HydrophobicContact CG1-CG 3.69Å; Y109-L113 PolarHBondContact O-N 3.37Å; W110-L113 PolarHBondContact O-N 3.37Å; L113-R115 VanDerWaalsContact C-N 3.31Å; L113-R115 PolarHBondContact O-N 2.72Å; L113-S116 PolarHBondContact O-N 3.16Å; L113-S116 VanDerWaalsContact O-N 3.15Å; L113-F119 HydrophobicContact CB-CD1 4.21Å; L113-F119 HydrophobicContact CB-CE1 3.97Å; L113-F119 HydrophobicContact CD2-CE1 4.4Å; L113-I147 HydrophobicContact CB-CD1 4.06Å; L113-I147 HydrophobicContact CD1-CD1 3.83Å; L113-I147 HydrophobicContact CD1-CG1 3.88Å
114	A	89.4	Confident	82.7	Confident	0 Å²	0	45 Å²	45	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-70.6	-21	-174.8	0	0	0	0	0	114.4	W110 Y111 S116 L120 I147 A166 N169 L170	W110-A114 HydrophobicContact CE3-CB 4.17Å; W110-A114 HydrophobicContact CZ3-CB 4.29Å; W110-A114 WeakPolarHBondContact O-CB 3.41Å; W110-A114 PolarHBondContact O-N 3.49Å; Y111-A114 PolarHBondContact O-N 2.86Å; A114-S116 VanDerWaalsContact C-N 3.27Å; A114-S116 PolarHBondContact O-N 2.93Å; A114-L120 WeakPolarHBondContact O-CD1 3.46Å; A114-I147 HydrophobicContact CB-CG2 4.32Å; A114-A166 HydrophobicContact CB-CB 3.86Å; A114-N169 VanDerWaalsContact O-CB 3.24Å; A114-N169 WeakPolarHBondContact O-CB 3.48Å; A114-N169 PolarHBondContact O-ND2 2.93Å; A114-L170 HydrophobicContact CB-CD1 3.78Å; A114-L170 HydrophobicContact CB-CD2 4Å; A114-L170 HydrophobicContact CB-CG 3.65Å
115	R	87	Confident	84.3	Confident	92 Å²	92	48.8 Å²	48.8	35%	0.347	22%	0.216	S	C	.	.	H	α-helix	trans	-65.9	-30.4	170.3	-80.6	-178	77.3	164.4	20	112.6	E53 Y111 L113 Q117 D162 A166 N169	E53-R115 IonicContact OE1-CZ 3.4Å; E53-R115 IonicContact OE1-NE 3.93Å; E53-R115 IonicContact OE1-NH1 3.55Å; E53-R115 PolarHBondContact OE1-NH1 3.04Å; E53-R115 IonicContact OE2-NH1 3.19Å; Y111-R115 WeakPolarHBondContact O-CB 3.33Å; Y111-R115 VanDerWaalsContact O-CG 3.25Å; Y111-R115 WeakPolarHBondContact O-CG 3.35Å; Y111-R115 PolarHBondContact O-N 3.44Å; L113-R115 VanDerWaalsContact C-N 3.31Å; L113-R115 PolarHBondContact O-N 2.72Å; R115-Q117 PolarHBondContact O-N 3.35Å; R115-Q117 VanDerWaalsContact O-N 3.14Å; R115-D162 IonicContact CZ-OD1 3.74Å; R115-D162 IonicContact NH1-OD1 3.98Å; R115-D162 PolarHBondContact NH1-OD1 2.94Å; R115-D162 IonicContact NH2-OD1 2.91Å; R115-A166 HydrophobicContact CG-CB 3.98Å; R115-N169 PolarHBondContact O-ND2 2.89Å
116	S	87.4	Confident	85.8	Confident	22 Å²	22	39.4 Å²	39.4	15%	0.154	18%	0.175	C	C	.	.			trans	-77.5	100.3	176.8	-179.5	0	0	0	0	110.4	L113 A114 E118 F119 L120	L113-S116 PolarHBondContact O-N 3.16Å; L113-S116 VanDerWaalsContact O-N 3.15Å; A114-S116 VanDerWaalsContact C-N 3.27Å; A114-S116 PolarHBondContact O-N 2.93Å; S116-E118 PolarHBondContact O-N 3.41Å; S116-F119 PolarHBondContact O-N 3.14Å; S116-F119 WeakPolarHBondContact OG-CB 3.42Å; S116-F119 PolarHBondContact OG-N 3.44Å; S116-L120 PolarHBondContact O-N 3.36Å; S116-L120 VanDerWaalsContact O-N 3.13Å
117	Q	89.5	Confident	87	Confident	92 Å²	92	38.6 Å²	38.6	43%	0.43	17%	0.17	S	C	.	.	H	α-helix	trans	-61.1	-33.8	174.5	-64.6	-170.3	-2.4	0	0	111.9	R115 L120 K121 N169 I173	R115-Q117 PolarHBondContact O-N 3.35Å; R115-Q117 VanDerWaalsContact O-N 3.14Å; Q117-L120 PolarHBondContact O-N 3.46Å; Q117-K121 WeakPolarHBondContact O-CB 3.49Å; Q117-K121 WeakPolarHBondContact O-CG 3.38Å; Q117-K121 PolarHBondContact O-N 3.37Å; Q117-N169 PolarHBondContact NE2-OD1 3.24Å; Q117-I173 HydrophobicContact CB-CD1 3.69Å; Q117-I173 HydrophobicContact CG-CD1 3.74Å
118	E	87.2	Confident	87.8	Confident	80 Å²	80	36.4 Å²	36.4	37%	0.374	17%	0.171	S	C	.	.	H	α-helix	trans	-63.9	-46	176.7	-65.7	-177.1	163.5	0	0	111.2	S116 L120 K121 C122	S116-E118 PolarHBondContact O-N 3.41Å; E118-L120 PolarHBondContact O-N 3.05Å; E118-K121 PolarHBondContact O-N 2.94Å; E118-C122 PolarHBondContact O-N 3.39Å; E118-C122 PolarHBondContact O-SG 2.98Å
119	F	90.2	Very high	88.3	Confident	0 Å²	0	39.5 Å²	39.5	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-58.8	-48.9	175.7	177.1	-105.9	0	0	0	111.6	F57 I78 L83 I86 L113 S116 K121 C122 L123 V143 I147	F57-F119 HydrophobicContact CB-CB 4.36Å; F57-F119 HydrophobicContact CB-CD2 4.49Å; F57-F119 AromaticContact CD1-CD2 3.98Å; F57-F119 HydrophobicContact CD1-CD2 3.98Å; F57-F119 HydrophobicContact CD2-CB 3.82Å; F57-F119 HydrophobicContact CD2-CD2 4.14Å; F57-F119 HydrophobicContact CD2-CG 4.37Å; F57-F119 HydrophobicContact CE1-CD2 4.28Å; F57-F119 HydrophobicContact CE2-CB 4.46Å; F57-F119 HydrophobicContact CE2-CD2 4.45Å; F57-F119 HydrophobicContact CG-CB 4.14Å; F57-F119 AromaticContact CG-CD2 3.91Å; F57-F119 HydrophobicContact CG-CD2 3.91Å; I78-F119 HydrophobicContact CD1-CD2 3.95Å; I78-F119 HydrophobicContact CD1-CE2 4.33Å; L83-F119 HydrophobicContact CD2-CE2 4.32Å; I86-F119 HydrophobicContact CD1-CE2 3.71Å; I86-F119 HydrophobicContact CD1-CZ 4.12Å; I86-F119 HydrophobicContact CG2-CZ 4.34Å; L113-F119 HydrophobicContact CB-CD1 4.21Å; L113-F119 HydrophobicContact CB-CE1 3.97Å; L113-F119 HydrophobicContact CD2-CE1 4.4Å; S116-F119 PolarHBondContact O-N 3.14Å; S116-F119 WeakPolarHBondContact OG-CB 3.42Å; S116-F119 PolarHBondContact OG-N 3.44Å; F119-K121 VanDerWaalsContact C-N 3.35Å; F119-K121 PolarHBondContact O-N 2.91Å; F119-C122 PolarHBondContact O-N 3.06Å; F119-L123 HydrophobicContact CD1-CD1 4.2Å; F119-L123 HydrophobicContact CE1-CD1 3.57Å; F119-L123 HydrophobicContact CE1-CG 4.27Å; F119-L123 HydrophobicContact CE2-CG 4.48Å; F119-L123 HydrophobicContact CZ-CD1 3.77Å; F119-L123 HydrophobicContact CZ-CD2 4.31Å; F119-L123 HydrophobicContact CZ-CG 4.16Å; F119-L123 PolarHBondContact O-N 3.41Å; F119-V143 HydrophobicContact CZ-CG1 4.09Å; F119-I147 HydrophobicContact CE1-CD1 3.74Å; F119-I147 HydrophobicContact CZ-CD1 4.46Å
120	L	92.2	Very high	88.3	Confident	0 Å²	0	37 Å²	37	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-61.7	-41.2	177.4	-66.3	-179.2	0	0	0	112.2	A114 S116 Q117 E118 L123 I124 N169 L170 I173 T174	A114-L120 WeakPolarHBondContact O-CD1 3.46Å; S116-L120 PolarHBondContact O-N 3.36Å; S116-L120 VanDerWaalsContact O-N 3.13Å; Q117-L120 PolarHBondContact O-N 3.46Å; E118-L120 PolarHBondContact O-N 3.05Å; L120-L123 PolarHBondContact O-N 2.86Å; L120-I124 WeakPolarHBondContact O-CG1 3.33Å; L120-I124 PolarHBondContact O-N 3.35Å; L120-N169 HydrophobicContact CD1-CB 4.1Å; L120-L170 HydrophobicContact CD1-CD2 3.95Å; L120-L170 HydrophobicContact CD1-CG 4.36Å; L120-L170 HydrophobicContact CD2-CD2 3.71Å; L120-I173 HydrophobicContact CB-CB 4.44Å; L120-I173 HydrophobicContact CB-CD1 4.16Å; L120-I173 HydrophobicContact CB-CG2 3.93Å; L120-I173 HydrophobicContact CD1-CD1 4.17Å; L120-T174 HydrophobicContact CD2-CG2 4.43Å
121	K	90.9	Very high	88.1	Confident	117 Å²	117	41.9 Å²	41.9	51%	0.509	20%	0.2	S	C	.	.	H	α-helix	trans	-63.2	-41.5	175.8	-76.9	171.7	-177.6	176.3	0	111.9	Q117 E118 F119 I124 Q125 I173	Q117-K121 WeakPolarHBondContact O-CB 3.49Å; Q117-K121 WeakPolarHBondContact O-CG 3.38Å; Q117-K121 PolarHBondContact O-N 3.37Å; E118-K121 PolarHBondContact O-N 2.94Å; F119-K121 VanDerWaalsContact C-N 3.35Å; F119-K121 PolarHBondContact O-N 2.91Å; K121-I124 PolarHBondContact O-N 3.46Å; K121-Q125 WeakPolarHBondContact O-CB 3.37Å; K121-Q125 PolarHBondContact O-N 3.28Å; K121-I173 HydrophobicContact CG-CG2 4.23Å
122	C	89.4	Confident	87.8	Confident	10 Å²	10	43.7 Å²	43.7	7%	0.068	23%	0.23	C	C	.	.	H	α-helix	trans	-61.2	-45.2	175.5	-67.3	0	0	0	0	111.1	M59 I78 E118 F119 I124 Q125 I126	M59-C122 HydrophobicContact CG-CB 4.48Å; M59-C122 HydrophobicContact SD-CB 4.2Å; I78-C122 HydrophobicContact CD1-CB 3.29Å; E118-C122 PolarHBondContact O-N 3.39Å; E118-C122 PolarHBondContact O-SG 2.98Å; F119-C122 PolarHBondContact O-N 3.06Å; C122-I124 PolarHBondContact O-N 3.34Å; C122-Q125 PolarHBondContact O-N 3.47Å; C122-Q125 VanDerWaalsContact O-N 3.14Å; C122-I126 WeakPolarHBondContact O-CD1 3.29Å; C122-I126 VanDerWaalsContact O-CG1 3.22Å; C122-I126 WeakPolarHBondContact O-CG1 3.38Å; C122-I126 PolarHBondContact O-N 2.87Å
123	L	92.4	Very high	87.6	Confident	0 Å²	0	44.7 Å²	44.7	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-57.5	-47.8	174.9	-68	179.8	0	0	0	111.7	L83 F119 L120 Q125 I126 I127 A140 V143 L144 I147	L83-L123 HydrophobicContact CD1-CD2 4.42Å; L83-L123 HydrophobicContact CD2-CD2 3.7Å; F119-L123 HydrophobicContact CD1-CD1 4.2Å; F119-L123 HydrophobicContact CE1-CD1 3.57Å; F119-L123 HydrophobicContact CE1-CG 4.27Å; F119-L123 HydrophobicContact CE2-CG 4.48Å; F119-L123 HydrophobicContact CZ-CD1 3.77Å; F119-L123 HydrophobicContact CZ-CD2 4.31Å; F119-L123 HydrophobicContact CZ-CG 4.16Å; F119-L123 PolarHBondContact O-N 3.41Å; L120-L123 PolarHBondContact O-N 2.86Å; L123-Q125 PolarHBondContact O-N 2.75Å; L123-I126 PolarHBondContact O-N 3.31Å; L123-I127 WeakPolarHBondContact O-CD1 3.4Å; L123-I127 WeakPolarHBondContact O-CG1 3.45Å; L123-I127 PolarHBondContact O-N 3.01Å; L123-A140 HydrophobicContact CD2-CB 4Å; L123-V143 HydrophobicContact CD1-CG1 4.26Å; L123-L144 HydrophobicContact CD1-CB 4.23Å; L123-I147 HydrophobicContact CD1-CD1 4.37Å
124	I	92.1	Very high	87.4	Confident	30 Å²	30	48.7 Å²	48.7	15%	0.154	26%	0.263	C	S	.	.	H	α-helix	trans	-65.4	-26.7	178.7	-65.3	-58.5	0	0	0	112.6	L120 K121 C122 I127 P128 L144 I173 T174 P177	L120-I124 WeakPolarHBondContact O-CG1 3.33Å; L120-I124 PolarHBondContact O-N 3.35Å; K121-I124 PolarHBondContact O-N 3.46Å; C122-I124 PolarHBondContact O-N 3.34Å; I124-I127 HydrophobicContact CD1-CD1 4.35Å; I124-P128 WeakPolarHBondContact O-CD 3.3Å; I124-P128 WeakPolarHBondContact O-CG 3.21Å; I124-L144 HydrophobicContact CD1-CD2 3.79Å; I124-I173 HydrophobicContact CG1-CG2 4.29Å; I124-T174 HydrophobicContact CD1-CG2 4.16Å; I124-T174 HydrophobicContact CG1-CG2 4.2Å; I124-P177 HydrophobicContact CD1-CB 3.95Å; I124-P177 HydrophobicContact CD1-CG 4.31Å; I124-P177 HydrophobicContact CG2-CB 4.15Å; I124-P177 HydrophobicContact CG2-CG 3.9Å
125	Q	90	Very high	87.1	Confident	100 Å²	100	53.6 Å²	53.6	47%	0.467	28%	0.282	S	S	.	.	H	α-helix	trans	-78	-38.6	174	-172.6	175.3	0.1	0	0	112.3	K121 C122 L123 P128 T129 Y131	K121-Q125 WeakPolarHBondContact O-CB 3.37Å; K121-Q125 PolarHBondContact O-N 3.28Å; C122-Q125 PolarHBondContact O-N 3.47Å; C122-Q125 VanDerWaalsContact O-N 3.14Å; L123-Q125 PolarHBondContact O-N 2.75Å; Q125-P128 WeakPolarHBondContact O-CD 3.34Å; Q125-T129 WeakPolarHBondContact O-CG2 3.46Å; Q125-T129 PolarHBondContact O-OG1 3.24Å; Q125-Y131 VanDerWaalsContact CD-OH 3.24Å; Q125-Y131 WeakPolarHBondContact CG-OH 3.23Å; Q125-Y131 PolarHBondContact NE2-OH 3.23Å
126	I	89.3	Confident	87	Confident	0 Å²	0	50.1 Å²	50.1	0%	0	27%	0.27	C	S	.	.	H	α-helix	trans	-67.8	-46.1	178.6	-65.5	159.1	0	0	0	111.1	M59 I78 L83 C122 L123 T129 G130 Y131 F136 A140	M59-I126 HydrophobicContact CE-CD1 4.13Å; M59-I126 HydrophobicContact CE-CG1 3.73Å; M59-I126 HydrophobicContact SD-CD1 3.54Å; M59-I126 VanDerWaalsContact SD-CD1 3.54Å; M59-I126 HydrophobicContact SD-CG1 3.47Å; M59-I126 WeakPolarHBondContact SD-CG1 3.4Å; I78-I126 HydrophobicContact CB-CD1 4.44Å; I78-I126 HydrophobicContact CG2-CD1 3.64Å; L83-I126 HydrophobicContact CD1-CD1 4.42Å; C122-I126 WeakPolarHBondContact O-CD1 3.29Å; C122-I126 VanDerWaalsContact O-CG1 3.22Å; C122-I126 WeakPolarHBondContact O-CG1 3.38Å; C122-I126 PolarHBondContact O-N 2.87Å; L123-I126 PolarHBondContact O-N 3.31Å; I126-T129 PolarHBondContact O-N 3.08Å; I126-T129 VanDerWaalsContact O-N 3.16Å; I126-T129 PolarHBondContact O-OG1 2.75Å; I126-G130 WeakPolarHBondContact O-CA 3.23Å; I126-G130 PolarHBondContact O-N 3.14Å; I126-Y131 HydrophobicContact CG1-CE2 4.08Å; I126-F136 HydrophobicContact CD1-CE1 4.24Å; I126-F136 HydrophobicContact CD1-CE2 3.81Å; I126-F136 HydrophobicContact CD1-CZ 3.53Å; I126-F136 HydrophobicContact CG1-CE1 3.97Å; I126-F136 HydrophobicContact CG1-CE2 4.33Å; I126-F136 HydrophobicContact CG1-CZ 3.78Å; I126-F136 HydrophobicContact CG2-CB 4.5Å; I126-F136 HydrophobicContact CG2-CD1 3.75Å; I126-F136 HydrophobicContact CG2-CD2 3.83Å; I126-F136 HydrophobicContact CG2-CE1 3.88Å; I126-F136 HydrophobicContact CG2-CE2 3.96Å; I126-F136 HydrophobicContact CG2-CG 3.73Å; I126-F136 HydrophobicContact CG2-CZ 3.98Å; I126-F136 WeakPolarHBondContact CG2-O 3.48Å; I126-A140 HydrophobicContact CB-CB 3.98Å; I126-A140 HydrophobicContact CG2-CB 3.59Å
127	I	89.9	Confident	86.9	Confident	1 Å²	1	51.2 Å²	51.2	1%	0.005	27%	0.273	C	S	.	.	H	α-helix	trans	-51.6	-50.2	-173.3	-70.5	159.5	0	0	0	113.6	L123 I124 Q137 A140 M141 L144 F181 I190	L123-I127 WeakPolarHBondContact O-CD1 3.4Å; L123-I127 WeakPolarHBondContact O-CG1 3.45Å; L123-I127 PolarHBondContact O-N 3.01Å; I124-I127 HydrophobicContact CD1-CD1 4.35Å; I127-Q137 WeakPolarHBondContact O-CG 3.48Å; I127-A140 HydrophobicContact CG1-CB 4.02Å; I127-M141 HydrophobicContact CD1-CB 4.49Å; I127-M141 HydrophobicContact CD1-SD 3.77Å; I127-M141 HydrophobicContact CG1-CB 4.19Å; I127-M141 HydrophobicContact CG1-SD 4.23Å; I127-M141 HydrophobicContact CG2-SD 4.08Å; I127-L144 HydrophobicContact CD1-CD2 3.66Å; I127-F181 HydrophobicContact CB-CE2 4.33Å; I127-F181 HydrophobicContact CB-CZ 4.46Å; I127-F181 HydrophobicContact CG2-CD2 4.1Å; I127-F181 HydrophobicContact CG2-CE1 4.38Å; I127-F181 HydrophobicContact CG2-CE2 3.62Å; I127-F181 HydrophobicContact CG2-CZ 3.79Å; I127-I190 HydrophobicContact CG2-CG2 4.34Å
128	P	86	Confident	86.7	Confident	74 Å²	74	50.6 Å²	50.6	48%	0.481	27%	0.27	S	S	.	.	H	α-helix	trans	-79.9	-25.6	-179.7	30.1	-35	0	0	0	113.7	I124 Q125 F181	I124-P128 WeakPolarHBondContact O-CD 3.3Å; I124-P128 WeakPolarHBondContact O-CG 3.21Å; Q125-P128 WeakPolarHBondContact O-CD 3.34Å; P128-F181 HydrophobicContact CB-CE1 4.33Å; P128-F181 HydrophobicContact CB-CZ 4.3Å; P128-F181 HydrophobicContact CG-CZ 4.41Å
129	T	85.7	Confident	86.7	Confident	68 Å²	68	47.3 Å²	47.3	42%	0.417	25%	0.254	S	S	.	.	H	α-helix	trans	-94.3	-39.6	-173.3	60.5	0	0	0	0	112.5	Q125 I126 Y131 Q137	Q125-T129 WeakPolarHBondContact O-CG2 3.46Å; Q125-T129 PolarHBondContact O-OG1 3.24Å; I126-T129 PolarHBondContact O-N 3.08Å; I126-T129 VanDerWaalsContact O-N 3.16Å; I126-T129 PolarHBondContact O-OG1 2.75Å; T129-Y131 PolarHBondContact O-N 3.45Å; T129-Y131 WeakPolarHBondContact OG1-CD2 3.09Å; T129-Y131 WeakPolarHBondContact OG1-CE2 3.38Å; T129-Q137 PolarHBondContact O-NE2 3.49Å
130	G	81.3	Confident	86.6	Confident	0 Å²	0	47.3 Å²	47.3	0%	0	25%	0.254	C	S	.	.	G	3₁₀ helix	trans	57.6	-5.3	-169.2	0	0	0	0	0	115.1	I126 G132 D133	I126-G130 WeakPolarHBondContact O-CA 3.23Å; I126-G130 PolarHBondContact O-N 3.14Å; G130-G132 PolarHBondContact O-N 3.28Å; G130-G132 VanDerWaalsContact O-N 3.12Å; G130-D133 PolarHBondContact O-N 3.35Å
131	Y	81.6	Confident	86.6	Confident	111 Å²	111	47.3 Å²	47.3	44%	0.435	25%	0.254	S	S	.	.	G	3₁₀ helix	trans	46	35.5	-164.5	-63.7	-91.4	0	0	0	113.2	M59 Q125 I126 T129 F136	M59-Y131 HydrophobicContact CE-CD2 3.77Å; M59-Y131 HydrophobicContact CE-CE2 3.27Å; M59-Y131 HydrophobicContact SD-CE2 4.28Å; Q125-Y131 VanDerWaalsContact CD-OH 3.24Å; Q125-Y131 WeakPolarHBondContact CG-OH 3.23Å; Q125-Y131 PolarHBondContact NE2-OH 3.23Å; I126-Y131 HydrophobicContact CG1-CE2 4.08Å; T129-Y131 PolarHBondContact O-N 3.45Å; T129-Y131 WeakPolarHBondContact OG1-CD2 3.09Å; T129-Y131 WeakPolarHBondContact OG1-CE2 3.38Å; Y131-F136 HydrophobicContact CD2-CD1 4.2Å; Y131-F136 AromaticContact CD2-CE1 3.89Å; Y131-F136 HydrophobicContact CD2-CE1 3.89Å
132	G	79.7	Confident	86.5	Confident	77 Å²	77	43.9 Å²	43.9	79%	0.794	24%	0.241	S	C	*	.	G	3₁₀ helix	trans	86.9	-4.9	-177.4	0	0	0	0	0	115.6	G130	G130-G132 PolarHBondContact O-N 3.28Å; G130-G132 VanDerWaalsContact O-N 3.12Å
133	D	82	Confident	86.5	Confident	65 Å²	65	43.4 Å²	43.4	35%	0.348	24%	0.238	S	C	.	.			trans	-107.9	113	175.2	-178.1	10.6	0	0	0	111.5	G130 Y135 F136 Q137	G130-D133 PolarHBondContact O-N 3.35Å; D133-Y135 VanDerWaalsContact C-N 3.25Å; D133-Y135 PolarHBondContact O-N 2.9Å; D133-Y135 VanDerWaalsContact OD1-CB 3.29Å; D133-Y135 WeakPolarHBondContact OD1-CB 3.23Å; D133-Y135 PolarHBondContact OD1-N 2.65Å; D133-F136 HydrophobicContact CB-CB 3.96Å; D133-F136 PolarHBondContact O-N 2.87Å; D133-Q137 PolarHBondContact O-N 3.26Å
134	P	82.7	Confident	86.6	Confident	84 Å²	84	43.4 Å²	43.4	55%	0.545	24%	0.238	S	C	.	.	H	α-helix	trans	-61.8	-33.7	175.1	26	-33.7	0	0	0	112.1	F136 Q137 E138	P134-F136 PolarHBondContact O-N 3.32Å; P134-Q137 WeakPolarHBondContact O-CB 3.46Å; P134-Q137 PolarHBondContact O-N 2.84Å; P134-Q137 VanDerWaalsContact O-N 3.13Å; P134-E138 WeakPolarHBondContact O-CG 3.26Å; P134-E138 PolarHBondContact O-N 2.84Å
135	Y	83	Confident	86.6	Confident	103 Å²	103	42.1 Å²	42.1	40%	0.404	23%	0.232	S	C	.	.	H	α-helix	trans	-63.9	-33.4	179	-176.1	-103.8	0	0	0	111.7	T80 K84 D133 E138 I139	T80-Y135 HydrophobicContact CG2-CD1 4.07Å; T80-Y135 HydrophobicContact CG2-CE1 4.44Å; K84-Y135 WeakPolarHBondContact CE-OH 3.26Å; D133-Y135 VanDerWaalsContact C-N 3.25Å; D133-Y135 PolarHBondContact O-N 2.9Å; D133-Y135 VanDerWaalsContact OD1-CB 3.29Å; D133-Y135 WeakPolarHBondContact OD1-CB 3.23Å; D133-Y135 PolarHBondContact OD1-N 2.65Å; Y135-E138 PolarHBondContact O-N 3.48Å; Y135-I139 WeakPolarHBondContact O-CG2 3.45Å; Y135-I139 PolarHBondContact O-N 3.3Å
136	F	84.8	Confident	86.5	Confident	18 Å²	18	38.8 Å²	38.8	8%	0.079	22%	0.217	C	C	.	.	H	α-helix	trans	-68.4	-36.5	176	-165.8	-156.4	0	0	0	112.3	M59 I78 T80 L83 I126 Y131 D133 P134 I139 A140	M59-F136 HydrophobicContact CE-CE1 3.81Å; M59-F136 HydrophobicContact CE-CZ 3.9Å; I78-F136 HydrophobicContact CG2-CE2 4.26Å; I78-F136 HydrophobicContact CG2-CZ 4.29Å; T80-F136 HydrophobicContact CG2-CB 4.04Å; T80-F136 HydrophobicContact CG2-CD2 3.71Å; T80-F136 HydrophobicContact CG2-CE2 4.45Å; T80-F136 HydrophobicContact CG2-CG 4.08Å; L83-F136 HydrophobicContact CD1-CD2 4.01Å; L83-F136 HydrophobicContact CD1-CE2 3.61Å; I126-F136 HydrophobicContact CD1-CE1 4.24Å; I126-F136 HydrophobicContact CD1-CE2 3.81Å; I126-F136 HydrophobicContact CD1-CZ 3.53Å; I126-F136 HydrophobicContact CG1-CE1 3.97Å; I126-F136 HydrophobicContact CG1-CE2 4.33Å; I126-F136 HydrophobicContact CG1-CZ 3.78Å; I126-F136 HydrophobicContact CG2-CB 4.5Å; I126-F136 HydrophobicContact CG2-CD1 3.75Å; I126-F136 HydrophobicContact CG2-CD2 3.83Å; I126-F136 HydrophobicContact CG2-CE1 3.88Å; I126-F136 HydrophobicContact CG2-CE2 3.96Å; I126-F136 HydrophobicContact CG2-CG 3.73Å; I126-F136 HydrophobicContact CG2-CZ 3.98Å; I126-F136 WeakPolarHBondContact CG2-O 3.48Å; Y131-F136 HydrophobicContact CD2-CD1 4.2Å; Y131-F136 AromaticContact CD2-CE1 3.89Å; Y131-F136 HydrophobicContact CD2-CE1 3.89Å; D133-F136 HydrophobicContact CB-CB 3.96Å; D133-F136 PolarHBondContact O-N 2.87Å; P134-F136 PolarHBondContact O-N 3.32Å; F136-I139 HydrophobicContact CD2-CG2 4.22Å; F136-A140 WeakPolarHBondContact O-CB 3.15Å; F136-A140 PolarHBondContact O-N 2.9Å
137	Q	85.6	Confident	86.6	Confident	46 Å²	46	38.8 Å²	38.8	22%	0.215	22%	0.217	C	C	.	.	H	α-helix	trans	-62.2	-49.2	171.4	-58	-179.9	-10	0	0	110.9	I127 T129 D133 P134 I139 A140 M141 I190	I127-Q137 WeakPolarHBondContact O-CG 3.48Å; T129-Q137 PolarHBondContact O-NE2 3.49Å; D133-Q137 PolarHBondContact O-N 3.26Å; P134-Q137 WeakPolarHBondContact O-CB 3.46Å; P134-Q137 PolarHBondContact O-N 2.84Å; P134-Q137 VanDerWaalsContact O-N 3.13Å; Q137-I139 PolarHBondContact O-N 3.17Å; Q137-A140 PolarHBondContact O-N 3.47Å; Q137-M141 WeakPolarHBondContact O-CB 3.27Å; Q137-M141 PolarHBondContact O-N 3.31Å; Q137-I190 HydrophobicContact CB-CD1 4.38Å
138	E	85.2	Confident	86.7	Confident	79 Å²	79	38.8 Å²	38.8	37%	0.369	22%	0.217	S	C	.	.	H	α-helix	trans	-59.7	-49.6	-177.3	-68	-168.4	167.9	0	0	111.5	P134 Y135 A140 M141 I142 W193	P134-E138 WeakPolarHBondContact O-CG 3.26Å; P134-E138 PolarHBondContact O-N 2.84Å; Y135-E138 PolarHBondContact O-N 3.48Å; E138-A140 PolarHBondContact O-N 3.15Å; E138-M141 PolarHBondContact O-N 3.44Å; E138-I142 VanDerWaalsContact O-CG1 3.24Å; E138-I142 WeakPolarHBondContact O-CG1 3.43Å; E138-I142 PolarHBondContact O-N 3.47Å; E138-W193 HydrophobicContact CB-CH2 3.66Å; E138-W193 HydrophobicContact CB-CZ3 3.7Å; E138-W193 HydrophobicContact CG-CH2 3.75Å; E138-W193 HydrophobicContact CG-CZ3 3.71Å
139	I	85.7	Confident	86.8	Confident	10 Å²	10	37.4 Å²	37.4	5%	0.051	21%	0.205	C	C	.	.	H	α-helix	trans	-68.9	-37.3	-177	-162	165.9	0	0	0	112.8	L83 K84 Y135 F136 Q137 M141 I142 V143	L83-I139 HydrophobicContact CB-CD1 4.23Å; L83-I139 HydrophobicContact CB-CG1 4.15Å; L83-I139 HydrophobicContact CB-CG2 4.14Å; L83-I139 HydrophobicContact CD1-CG2 3.83Å; K84-I139 HydrophobicContact CB-CD1 4.1Å; K84-I139 HydrophobicContact CD-CD1 4.36Å; K84-I139 HydrophobicContact CG-CD1 3.19Å; Y135-I139 WeakPolarHBondContact O-CG2 3.45Å; Y135-I139 PolarHBondContact O-N 3.3Å; F136-I139 HydrophobicContact CD2-CG2 4.22Å; Q137-I139 PolarHBondContact O-N 3.17Å; I139-M141 VanDerWaalsContact C-N 3.31Å; I139-M141 PolarHBondContact O-N 3.27Å; I139-I142 PolarHBondContact O-N 3.45Å; I139-V143 HydrophobicContact CG1-CG2 4.49Å; I139-V143 WeakPolarHBondContact O-CG2 3.47Å; I139-V143 PolarHBondContact O-N 3.01Å
140	A	89.6	Confident	86.8	Confident	0 Å²	0	34.7 Å²	34.7	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-62	-42.1	173.8	0	0	0	0	0	111.3	L83 L123 I126 I127 F136 Q137 E138 V143 L144	L83-A140 HydrophobicContact CD1-CB 3.96Å; L123-A140 HydrophobicContact CD2-CB 4Å; I126-A140 HydrophobicContact CB-CB 3.98Å; I126-A140 HydrophobicContact CG2-CB 3.59Å; I127-A140 HydrophobicContact CG1-CB 4.02Å; F136-A140 WeakPolarHBondContact O-CB 3.15Å; F136-A140 PolarHBondContact O-N 2.9Å; Q137-A140 PolarHBondContact O-N 3.47Å; E138-A140 PolarHBondContact O-N 3.15Å; A140-V143 PolarHBondContact O-N 3.37Å; A140-L144 WeakPolarHBondContact O-CB 3.47Å; A140-L144 PolarHBondContact O-N 3.38Å
141	M	91.6	Very high	87.1	Confident	0 Å²	0	34.7 Å²	34.7	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-66.4	-40.7	176.3	-168.3	64.8	-125.3	0	0	112	I127 Q137 E138 I139 L144 T145 L178 I190 W193 A197	I127-M141 HydrophobicContact CD1-CB 4.49Å; I127-M141 HydrophobicContact CD1-SD 3.77Å; I127-M141 HydrophobicContact CG1-CB 4.19Å; I127-M141 HydrophobicContact CG1-SD 4.23Å; I127-M141 HydrophobicContact CG2-SD 4.08Å; Q137-M141 WeakPolarHBondContact O-CB 3.27Å; Q137-M141 PolarHBondContact O-N 3.31Å; E138-M141 PolarHBondContact O-N 3.44Å; I139-M141 VanDerWaalsContact C-N 3.31Å; I139-M141 PolarHBondContact O-N 3.27Å; M141-L144 HydrophobicContact CE-CD2 4.26Å; M141-L144 PolarHBondContact O-N 3.02Å; M141-T145 VanDerWaalsContact CE-OG1 3.29Å; M141-T145 WeakPolarHBondContact CE-OG1 3.42Å; M141-T145 VanDerWaalsContact O-CB 3.28Å; M141-T145 WeakPolarHBondContact O-CB 3.43Å; M141-T145 PolarHBondContact O-N 3Å; M141-T145 PolarHBondContact O-OG1 2.79Å; M141-L178 HydrophobicContact CE-CD2 3.64Å; M141-I190 HydrophobicContact CG-CG2 4.31Å; M141-I190 HydrophobicContact SD-CG2 4.27Å; M141-W193 HydrophobicContact CB-CE3 3.93Å; M141-W193 HydrophobicContact CE-CB 4.13Å; M141-W193 HydrophobicContact CG-CB 3.57Å; M141-W193 HydrophobicContact CG-CD2 4.32Å; M141-W193 HydrophobicContact CG-CE3 3.79Å; M141-W193 HydrophobicContact CG-CG 4.32Å; M141-A197 HydrophobicContact CE-CB 4.13Å
142	I	88.7	Confident	87.2	Confident	46 Å²	46	29.9 Å²	29.9	24%	0.236	17%	0.172	C	C	.	.	H	α-helix	trans	-61	-47.1	175.2	-71.1	164.5	0	0	0	110.8	E138 I139 T145 N146 W193	E138-I142 VanDerWaalsContact O-CG1 3.24Å; E138-I142 WeakPolarHBondContact O-CG1 3.43Å; E138-I142 PolarHBondContact O-N 3.47Å; I139-I142 PolarHBondContact O-N 3.45Å; I142-T145 PolarHBondContact O-N 2.86Å; I142-N146 WeakPolarHBondContact O-CB 3.45Å; I142-N146 PolarHBondContact O-N 3.26Å; I142-W193 HydrophobicContact CD1-CH2 4Å; I142-W193 HydrophobicContact CD1-CZ2 3.69Å; I142-W193 HydrophobicContact CG1-CD2 4.11Å; I142-W193 HydrophobicContact CG1-CE3 4.47Å; I142-W193 HydrophobicContact CG1-CH2 4.1Å; I142-W193 HydrophobicContact CG1-CZ2 3.67Å; I142-W193 HydrophobicContact CG1-CZ3 4.49Å
143	V	89.8	Confident	87.3	Confident	0 Å²	0	31.3 Å²	31.3	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-60.1	-49.3	178.7	173.2	0	0	0	0	110.2	L83 I86 N87 F119 L123 I139 A140 T145 N146 I147	L83-V143 HydrophobicContact CB-CG2 4.14Å; L83-V143 HydrophobicContact CD2-CG2 4.28Å; I86-V143 HydrophobicContact CG2-CG1 4.18Å; N87-V143 HydrophobicContact CB-CG2 3.92Å; F119-V143 HydrophobicContact CZ-CG1 4.09Å; L123-V143 HydrophobicContact CD1-CG1 4.26Å; I139-V143 HydrophobicContact CG1-CG2 4.49Å; I139-V143 WeakPolarHBondContact O-CG2 3.47Å; I139-V143 PolarHBondContact O-N 3.01Å; A140-V143 PolarHBondContact O-N 3.37Å; V143-T145 VanDerWaalsContact C-N 3.31Å; V143-T145 PolarHBondContact O-N 3.37Å; V143-N146 PolarHBondContact O-N 2.8Å; V143-I147 HydrophobicContact CG1-CD1 3.95Å; V143-I147 VanDerWaalsContact O-CG1 3.3Å; V143-I147 WeakPolarHBondContact O-CG1 3.21Å; V143-I147 PolarHBondContact O-N 2.98Å
144	L	93.5	Very high	86.3	Confident	0 Å²	0	36.9 Å²	36.9	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-58.4	-44.6	177	177.7	58.3	0	0	0	111.6	L123 I124 I127 A140 M141 N146 I147 C148 T174 L178	L123-L144 HydrophobicContact CD1-CB 4.23Å; I124-L144 HydrophobicContact CD1-CD2 3.79Å; I127-L144 HydrophobicContact CD1-CD2 3.66Å; A140-L144 WeakPolarHBondContact O-CB 3.47Å; A140-L144 PolarHBondContact O-N 3.38Å; M141-L144 HydrophobicContact CE-CD2 4.26Å; M141-L144 PolarHBondContact O-N 3.02Å; L144-N146 PolarHBondContact O-N 3.46Å; L144-I147 PolarHBondContact O-N 3.42Å; L144-C148 PolarHBondContact O-N 2.73Å; L144-C148 PolarHBondContact O-SG 3.15Å; L144-T174 HydrophobicContact CD1-CG2 3.84Å; L144-L178 HydrophobicContact CD2-CD2 3.94Å; L144-L178 HydrophobicContact CD2-CG 4.49Å
145	T	92.1	Very high	85	Confident	3 Å²	3	33.9 Å²	33.9	2%	0.018	16%	0.155	C	C	.	.	H	α-helix	trans	-60.3	-46.3	178.7	-58.6	0	0	0	0	111.4	M141 I142 V143 I147 C148 I149 W193 Q196 A197	M141-T145 VanDerWaalsContact CE-OG1 3.29Å; M141-T145 WeakPolarHBondContact CE-OG1 3.42Å; M141-T145 VanDerWaalsContact O-CB 3.28Å; M141-T145 WeakPolarHBondContact O-CB 3.43Å; M141-T145 PolarHBondContact O-N 3Å; M141-T145 PolarHBondContact O-OG1 2.79Å; I142-T145 PolarHBondContact O-N 2.86Å; V143-T145 VanDerWaalsContact C-N 3.31Å; V143-T145 PolarHBondContact O-N 3.37Å; T145-I147 PolarHBondContact O-N 3.43Å; T145-C148 PolarHBondContact O-N 3.39Å; T145-I149 HydrophobicContact CG2-CD1 3.7Å; T145-I149 HydrophobicContact CG2-CG1 4.34Å; T145-I149 WeakPolarHBondContact O-CB 3.47Å; T145-I149 VanDerWaalsContact O-CG1 3.3Å; T145-I149 WeakPolarHBondContact O-CG1 3.42Å; T145-I149 PolarHBondContact O-N 3.47Å; T145-W193 WeakPolarHBondContact OG1-CB 3.49Å; T145-W193 PolarHBondContact OG1-O 2.89Å; T145-Q196 HydrophobicContact CG2-CB 3.84Å; T145-A197 HydrophobicContact CG2-CB 4.33Å
146	N	89.3	Confident	83.5	Confident	30 Å²	30	38.9 Å²	38.9	16%	0.16	18%	0.179	C	C	.	.	H	α-helix	trans	-66.3	-37.5	178.9	-74.2	-20.5	0	0	0	112.3	N87 L90 I142 V143 L144 C148 I149 L150	N87-N146 PolarHBondContact OD1-ND2 3.42Å; L90-N146 HydrophobicContact CD2-CB 3.9Å; I142-N146 WeakPolarHBondContact O-CB 3.45Å; I142-N146 PolarHBondContact O-N 3.26Å; V143-N146 PolarHBondContact O-N 2.8Å; L144-N146 PolarHBondContact O-N 3.46Å; N146-C148 PolarHBondContact O-N 2.91Å; N146-I149 PolarHBondContact O-N 3.23Å; N146-L150 VanDerWaalsContact O-CB 3.29Å; N146-L150 WeakPolarHBondContact O-CB 3.32Å; N146-L150 WeakPolarHBondContact O-CD1 3.4Å; N146-L150 WeakPolarHBondContact O-CG 3.04Å; N146-L150 PolarHBondContact O-N 3.3Å
147	I	91.3	Very high	82	Confident	0 Å²	0	44.1 Å²	44.1	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-58.4	-48.9	172.9	-68.8	166.2	0	0	0	110.4	L90 W110 L113 A114 F119 L123 V143 L144 T145 L150 A151 L170	L90-I147 HydrophobicContact CD2-CG1 3.78Å; W110-I147 HydrophobicContact CB-CG2 4.4Å; L113-I147 HydrophobicContact CB-CD1 4.06Å; L113-I147 HydrophobicContact CD1-CD1 3.83Å; L113-I147 HydrophobicContact CD1-CG1 3.88Å; A114-I147 HydrophobicContact CB-CG2 4.32Å; F119-I147 HydrophobicContact CE1-CD1 3.74Å; F119-I147 HydrophobicContact CZ-CD1 4.46Å; L123-I147 HydrophobicContact CD1-CD1 4.37Å; V143-I147 HydrophobicContact CG1-CD1 3.95Å; V143-I147 VanDerWaalsContact O-CG1 3.3Å; V143-I147 WeakPolarHBondContact O-CG1 3.21Å; V143-I147 PolarHBondContact O-N 2.98Å; L144-I147 PolarHBondContact O-N 3.42Å; T145-I147 PolarHBondContact O-N 3.43Å; I147-L150 PolarHBondContact O-N 3.46Å; I147-A151 WeakPolarHBondContact O-CB 3.21Å; I147-A151 PolarHBondContact O-N 3.2Å; I147-L170 HydrophobicContact CG2-CD1 4.07Å; I147-L170 HydrophobicContact CG2-CD2 3.88Å
148	C	91.4	Very high	80.4	Confident	0 Å²	0	43.8 Å²	43.8	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-65.5	-42.8	179.3	-68.8	0	0	0	0	112.6	L144 T145 N146 A151 G152 A197 G200	L144-C148 PolarHBondContact O-N 2.73Å; L144-C148 PolarHBondContact O-SG 3.15Å; T145-C148 PolarHBondContact O-N 3.39Å; N146-C148 PolarHBondContact O-N 2.91Å; C148-A151 PolarHBondContact O-N 3.49Å; C148-G152 PolarHBondContact O-N 2.9Å; C148-G152 VanDerWaalsContact O-N 3.09Å; C148-A197 HydrophobicContact CB-CB 4.15Å; C148-A197 VanDerWaalsContact CB-O 3.25Å; C148-A197 WeakPolarHBondContact CB-O 3.4Å; C148-G200 CarbonylContact O-C 3.56Å; C148-G200 VanDerWaalsContact O-CA 3.27Å; C148-G200 WeakPolarHBondContact O-CA 3.42Å
149	I	87.2	Confident	79	Confident	45 Å²	45	47.5 Å²	47.5	23%	0.231	22%	0.223	C	C	.	.	H	α-helix	trans	-61.8	-46.1	177.8	-73.1	173	0	0	0	110.7	T145 N146 G152 Y153 Q196	T145-I149 HydrophobicContact CG2-CD1 3.7Å; T145-I149 HydrophobicContact CG2-CG1 4.34Å; T145-I149 WeakPolarHBondContact O-CB 3.47Å; T145-I149 VanDerWaalsContact O-CG1 3.3Å; T145-I149 WeakPolarHBondContact O-CG1 3.42Å; T145-I149 PolarHBondContact O-N 3.47Å; N146-I149 PolarHBondContact O-N 3.23Å; I149-G152 CarbonylContact O-C 3.56Å; I149-G152 WeakPolarHBondContact O-CA 3.42Å; I149-G152 PolarHBondContact O-N 2.9Å; I149-Y153 HydrophobicContact CG2-CD2 4Å; I149-Y153 HydrophobicContact CG2-CE2 3.36Å; I149-Y153 WeakPolarHBondContact O-CD2 3.04Å; I149-Y153 PolarHBondContact O-N 3.01Å; I149-Q196 HydrophobicContact CD1-CB 4.45Å
150	L	86.9	Confident	78.3	Confident	12 Å²	12	48.7 Å²	48.7	6%	0.063	23%	0.232	C	C	.	.	H	α-helix	trans	-68.1	-35.9	179.9	-70.9	170.1	0	0	0	112.6	L90 D94 W110 N146 I147 G152 Y153	L90-L150 HydrophobicContact CD1-CD1 3.51Å; L90-L150 HydrophobicContact CD2-CD1 3.77Å; L90-L150 HydrophobicContact CG-CD1 3.29Å; D94-L150 HydrophobicContact CB-CD2 3.69Å; D94-L150 VanDerWaalsContact OD2-CD2 3.23Å; D94-L150 WeakPolarHBondContact OD2-CD2 3.36Å; W110-L150 HydrophobicContact CB-CB 4.17Å; W110-L150 HydrophobicContact CG-CB 4.45Å; N146-L150 VanDerWaalsContact O-CB 3.29Å; N146-L150 WeakPolarHBondContact O-CB 3.32Å; N146-L150 WeakPolarHBondContact O-CD1 3.4Å; N146-L150 WeakPolarHBondContact O-CG 3.04Å; N146-L150 PolarHBondContact O-N 3.3Å; I147-L150 PolarHBondContact O-N 3.46Å; L150-G152 PolarHBondContact O-N 2.93Å; L150-Y153 HydrophobicContact CD2-CD2 4.3Å; L150-Y153 PolarHBondContact O-N 3.44Å
151	A	86.4	Confident	77.8	Confident	0 Å²	0	55 Å²	55	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-59.5	-33.6	169.6	0	0	0	0	0	111.8	W110 I147 C148 L170 A204	W110-A151 HydrophobicContact CD2-CB 3.71Å; W110-A151 HydrophobicContact CE3-CB 3.59Å; W110-A151 HydrophobicContact CG-CB 4.4Å; W110-A151 HydrophobicContact CH2-CB 4.07Å; W110-A151 HydrophobicContact CZ2-CB 4.19Å; W110-A151 HydrophobicContact CZ3-CB 3.77Å; I147-A151 WeakPolarHBondContact O-CB 3.21Å; I147-A151 PolarHBondContact O-N 3.2Å; C148-A151 PolarHBondContact O-N 3.49Å; A151-L170 HydrophobicContact CB-CD1 4.4Å; A151-A204 HydrophobicContact CB-CB 3.79Å; A151-A204 WeakPolarHBondContact O-CB 3.38Å
152	G	84.9	Confident	77.4	Confident	9 Å²	9	58 Å²	58	9%	0.093	28%	0.282	C	S	.	.	T	Hydrogen-bonded Turn	trans	-81.7	-8.1	179.2	0	0	0	0	0	115.8	C148 I149 L150 G200 I207	C148-G152 PolarHBondContact O-N 2.9Å; C148-G152 VanDerWaalsContact O-N 3.09Å; I149-G152 CarbonylContact O-C 3.56Å; I149-G152 WeakPolarHBondContact O-CA 3.42Å; I149-G152 PolarHBondContact O-N 2.9Å; L150-G152 PolarHBondContact O-N 2.93Å; G152-G200 WeakPolarHBondContact CA-O 3.34Å; G152-I207 WeakPolarHBondContact O-CD1 3.36Å
153	Y	80.7	Confident	77.3	Confident	108 Å²	108	55.8 Å²	55.8	42%	0.424	27%	0.271	S	S	.	.	S	Bend	trans	-86.6	143.5	168.5	-72.8	-58.9	0	0	0	110.4	I149 L150 T155	I149-Y153 HydrophobicContact CG2-CD2 4Å; I149-Y153 HydrophobicContact CG2-CE2 3.36Å; I149-Y153 WeakPolarHBondContact O-CD2 3.04Å; I149-Y153 PolarHBondContact O-N 3.01Å; L150-Y153 HydrophobicContact CD2-CD2 4.3Å; L150-Y153 PolarHBondContact O-N 3.44Å; Y153-T155 PolarHBondContact O-N 3.01Å
154	K	61.7	Low	77	Confident	181 Å²	181	59.2 Å²	59.2	79%	0.787	29%	0.287	S	S	*	.			trans	-66.2	82.5	169.8	-75	-171	178.4	-176.1	0	109.2	I207	K154-I207 HydrophobicContact CG-CD1 4.03Å; K154-I207 HydrophobicContact CG-CG1 4.41Å
155	T	54.7	Low	76.7	Confident	22 Å²	22	61 Å²	61	14%	0.135	30%	0.299	C	S	.	.			trans	-66.9	145.6	166.8	61.3	0	0	0	0	107.9	Y153 Y157 S158	Y153-T155 PolarHBondContact O-N 3.01Å; T155-Y157 PolarHBondContact O-N 2.95Å; T155-S158 PolarHBondContact O-N 3.49Å
156	K	52.6	Low	76.6	Confident	207 Å²	207	60.8 Å²	60.8	90%	0.9	30%	0.298	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.6	-4	177.9	-71.2	179.9	177.3	177.3	0	114.2
157	Y	52.7	Low	76.6	Confident	128 Å²	128	59.4 Å²	59.4	50%	0.502	29%	0.29	S	S	.	.	T	Hydrogen-bonded Turn	trans	-112	21.5	-171.9	-55.7	-74.9	0	0	0	113.1	Y109 T155 I159	Y109-Y157 HydrophobicContact CE1-CE2 4.2Å; T155-Y157 PolarHBondContact O-N 2.95Å; Y157-I159 PolarHBondContact O-N 3.4Å
158	S	53.3	Low	76.5	Confident	40 Å²	40	64.8 Å²	64.8	28%	0.28	32%	0.316	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.9	5.4	-167	69.5	0	0	0	0	117	T155 Y208	T155-S158 PolarHBondContact O-N 3.49Å; S158-Y208 WeakPolarHBondContact O-CD1 3.4Å; S158-Y208 WeakPolarHBondContact O-CE1 3.48Å
159	I	55.6	Low	76.5	Confident	156 Å²	156	66.1 Å²	66.1	80%	0.8	32%	0.323	S	S	*	.	T	Hydrogen-bonded Turn	trans	-133.9	40.1	-173.7	-37.7	179.6	0	0	0	111.8	Y157	Y157-I159 PolarHBondContact O-N 3.4Å
160	S	70.9	Confident	76.8	Confident	36 Å²	36	64 Å²	64	25%	0.252	31%	0.312	S	S	.	.			trans	-99.2	145.5	166.4	72.1	0	0	0	0	111.1	D162 C163 Q164	S160-D162 PolarHBondContact O-N 2.96Å; S160-C163 PolarHBondContact O-N 3.34Å; S160-C163 PolarHBondContact OG-N 3.27Å; S160-C163 PolarHBondContact OG-SG 2.86Å; S160-Q164 PolarHBondContact O-N 3.37Å
161	N	78.6	Confident	77	Confident	133 Å²	133	64.8 Å²	64.8	71%	0.711	32%	0.316	S	S	*	.	H	α-helix	trans	-57.1	-30.3	170.7	-70.8	-10	0	0	0	111.4	Q164 S165	N161-Q164 PolarHBondContact O-N 2.98Å; N161-S165 PolarHBondContact O-N 3.37Å; N161-S165 PolarHBondContact O-OG 3.02Å
162	D	82.8	Confident	77.2	Confident	61 Å²	61	72.6 Å²	72.6	33%	0.326	35%	0.352	S	S	.	.	H	α-helix	trans	-62.4	-46	176.9	-61.9	-43.3	0	0	0	111.6	Y111 R115 S160 Q164 S165 A166	Y111-D162 HydrophobicContact CD2-CB 4.16Å; Y111-D162 HydrophobicContact CE2-CB 4.45Å; R115-D162 IonicContact CZ-OD1 3.74Å; R115-D162 IonicContact NH1-OD1 3.98Å; R115-D162 PolarHBondContact NH1-OD1 2.94Å; R115-D162 IonicContact NH2-OD1 2.91Å; S160-D162 PolarHBondContact O-N 2.96Å; D162-Q164 VanDerWaalsContact C-N 3.35Å; D162-Q164 PolarHBondContact O-N 3.15Å; D162-S165 PolarHBondContact O-N 3Å; D162-S165 PolarHBondContact O-OG 3.48Å; D162-A166 VanDerWaalsContact O-CB 3.29Å; D162-A166 WeakPolarHBondContact O-CB 3.48Å; D162-A166 PolarHBondContact O-N 2.78Å
163	C	86.1	Confident	77.5	Confident	0 Å²	0	73.2 Å²	73.2	0%	0	35%	0.353	C	S	.	.	H	α-helix	trans	-61.9	-40.7	177.1	-71.6	0	0	0	0	112.1	W110 S160 A166 L167 Y208	W110-C163 HydrophobicContact CH2-CB 4.19Å; W110-C163 WeakPolarHBondContact CH2-O 3.19Å; W110-C163 HydrophobicContact CZ2-CB 3.96Å; S160-C163 PolarHBondContact O-N 3.34Å; S160-C163 PolarHBondContact OG-N 3.27Å; S160-C163 PolarHBondContact OG-SG 2.86Å; C163-A166 PolarHBondContact O-N 2.77Å; C163-L167 WeakPolarHBondContact O-CB 3.26Å; C163-L167 PolarHBondContact O-N 3.07Å; C163-Y208 HydrophobicContact CB-CD1 4.33Å; C163-Y208 HydrophobicContact CB-CE1 3.54Å
164	Q	85	Confident	78.2	Confident	72 Å²	72	68.1 Å²	68.1	34%	0.336	33%	0.333	S	S	.	.	H	α-helix	trans	-65.3	-44.7	177	-70.7	-176.7	-14.6	0	0	111.7	S160 N161 D162 A166 L167 Q168 Y208	S160-Q164 PolarHBondContact O-N 3.37Å; N161-Q164 PolarHBondContact O-N 2.98Å; D162-Q164 VanDerWaalsContact C-N 3.35Å; D162-Q164 PolarHBondContact O-N 3.15Å; Q164-A166 VanDerWaalsContact C-N 3.34Å; Q164-A166 PolarHBondContact O-N 2.66Å; Q164-L167 PolarHBondContact O-N 3Å; Q164-Q168 WeakPolarHBondContact O-CG 3.47Å; Q164-Q168 PolarHBondContact O-N 2.69Å; Q164-Y208 HydrophobicContact CG-CD1 4.44Å
165	S	86.2	Confident	79.6	Confident	37 Å²	37	59.6 Å²	59.6	26%	0.259	30%	0.296	S	S	.	.	H	α-helix	trans	-63.3	-40.3	176.7	73.1	0	0	0	0	112.3	N161 D162 Q168 N169	N161-S165 PolarHBondContact O-N 3.37Å; N161-S165 PolarHBondContact O-OG 3.02Å; D162-S165 PolarHBondContact O-N 3Å; D162-S165 PolarHBondContact O-OG 3.48Å; S165-Q168 PolarHBondContact O-N 3.49Å; S165-N169 PolarHBondContact O-N 3.34Å
166	A	89.3	Confident	81.4	Confident	0 Å²	0	59.5 Å²	59.5	0%	0	30%	0.3	C	S	.	.	H	α-helix	trans	-63.4	-42.5	175.9	0	0	0	0	0	111.6	W110 Y111 A114 R115 D162 C163 Q164 N169 L170	W110-A166 HydrophobicContact CH2-CB 4.11Å; W110-A166 HydrophobicContact CZ3-CB 3.74Å; Y111-A166 WeakPolarHBondContact O-CB 3.44Å; A114-A166 HydrophobicContact CB-CB 3.86Å; R115-A166 HydrophobicContact CG-CB 3.98Å; D162-A166 VanDerWaalsContact O-CB 3.29Å; D162-A166 WeakPolarHBondContact O-CB 3.48Å; D162-A166 PolarHBondContact O-N 2.78Å; C163-A166 PolarHBondContact O-N 2.77Å; Q164-A166 VanDerWaalsContact C-N 3.34Å; Q164-A166 PolarHBondContact O-N 2.66Å; A166-N169 PolarHBondContact O-N 2.78Å; A166-L170 WeakPolarHBondContact O-CG 3.42Å; A166-L170 PolarHBondContact O-N 2.89Å
167	L	90.4	Very high	83.3	Confident	0 Å²	0	51.3 Å²	51.3	0%	0	27%	0.268	C	S	.	.	H	α-helix	trans	-64.1	-41.2	175.8	178.7	61.4	0	0	0	111.9	C163 Q164 N169 L170 I171 L201 A204 Y208 Y209	C163-L167 WeakPolarHBondContact O-CB 3.26Å; C163-L167 PolarHBondContact O-N 3.07Å; Q164-L167 PolarHBondContact O-N 3Å; L167-N169 VanDerWaalsContact C-N 3.34Å; L167-N169 PolarHBondContact O-N 3.23Å; L167-L170 WeakPolarHBondContact O-CB 3.35Å; L167-L170 PolarHBondContact O-N 3.47Å; L167-I171 HydrophobicContact CD1-CD1 4.09Å; L167-I171 HydrophobicContact CD1-CG1 4.22Å; L167-I171 HydrophobicContact CG-CD1 3.91Å; L167-I171 HydrophobicContact CG-CG1 4.47Å; L167-I171 WeakPolarHBondContact O-CG1 3.46Å; L167-I171 PolarHBondContact O-N 3.14Å; L167-L201 HydrophobicContact CD1-CD1 3.9Å; L167-A204 HydrophobicContact CD1-CB 3.79Å; L167-Y208 HydrophobicContact CD2-CD2 3.71Å; L167-Y208 HydrophobicContact CD2-CG 3.93Å; L167-Y209 HydrophobicContact CD2-CD2 3.98Å; L167-Y209 HydrophobicContact CD2-CE2 3.57Å; L167-Y209 HydrophobicContact CG-CE2 4.29Å
168	Q	89.8	Confident	85.3	Confident	114 Å²	114	45.2 Å²	45.2	53%	0.533	24%	0.244	S	C	.	.	H	α-helix	trans	-60.5	-43.2	175.2	-74.2	179.6	-10.3	0	0	111.9	Q164 S165 I171 H172 Y209	Q164-Q168 WeakPolarHBondContact O-CG 3.47Å; Q164-Q168 PolarHBondContact O-N 2.69Å; S165-Q168 PolarHBondContact O-N 3.49Å; Q168-I171 PolarHBondContact O-N 3.43Å; Q168-H172 VanDerWaalsContact O-CB 3.29Å; Q168-H172 WeakPolarHBondContact O-CB 3.33Å; Q168-H172 PolarHBondContact O-N 3.39Å; Q168-Y209 WeakPolarHBondContact CG-OH 3.49Å; Q168-Y209 PolarHBondContact NE2-OH 3.15Å
169	N	91.3	Very high	87.2	Confident	28 Å²	28	43.5 Å²	43.5	15%	0.15	23%	0.232	C	C	.	.	H	α-helix	trans	-61.7	-43.9	174.5	-77.6	-15.6	0	0	0	111.9	A114 R115 Q117 L120 S165 A166 L167 H172 I173	A114-N169 VanDerWaalsContact O-CB 3.24Å; A114-N169 WeakPolarHBondContact O-CB 3.48Å; A114-N169 PolarHBondContact O-ND2 2.93Å; R115-N169 PolarHBondContact O-ND2 2.89Å; Q117-N169 PolarHBondContact NE2-OD1 3.24Å; L120-N169 HydrophobicContact CD1-CB 4.1Å; S165-N169 PolarHBondContact O-N 3.34Å; A166-N169 PolarHBondContact O-N 2.78Å; L167-N169 VanDerWaalsContact C-N 3.34Å; L167-N169 PolarHBondContact O-N 3.23Å; N169-H172 PolarHBondContact O-N 3.48Å; N169-I173 VanDerWaalsContact O-CB 3.31Å; N169-I173 WeakPolarHBondContact O-CB 3.31Å; N169-I173 WeakPolarHBondContact O-CG1 3.3Å; N169-I173 PolarHBondContact O-N 3.43Å
170	L	93.2	Very high	88.8	Confident	0 Å²	0	41.1 Å²	41.1	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-57.6	-52.6	174.7	-75.9	170.1	0	0	0	111	W110 A114 L120 I147 A151 A166 L167 H172 I173 T174 L201	W110-L170 HydrophobicContact CE3-CD1 4.06Å; W110-L170 HydrophobicContact CZ3-CD1 3.86Å; A114-L170 HydrophobicContact CB-CD1 3.78Å; A114-L170 HydrophobicContact CB-CD2 4Å; A114-L170 HydrophobicContact CB-CG 3.65Å; L120-L170 HydrophobicContact CD1-CD2 3.95Å; L120-L170 HydrophobicContact CD1-CG 4.36Å; L120-L170 HydrophobicContact CD2-CD2 3.71Å; I147-L170 HydrophobicContact CG2-CD1 4.07Å; I147-L170 HydrophobicContact CG2-CD2 3.88Å; A151-L170 HydrophobicContact CB-CD1 4.4Å; A166-L170 WeakPolarHBondContact O-CG 3.42Å; A166-L170 PolarHBondContact O-N 2.89Å; L167-L170 WeakPolarHBondContact O-CB 3.35Å; L167-L170 PolarHBondContact O-N 3.47Å; L170-H172 PolarHBondContact O-N 2.87Å; L170-I173 PolarHBondContact O-N 2.9Å; L170-T174 HydrophobicContact CD2-CG2 4.41Å; L170-T174 WeakPolarHBondContact O-CB 3.21Å; L170-T174 PolarHBondContact O-N 2.69Å; L170-T174 PolarHBondContact O-OG1 2.91Å; L170-L201 HydrophobicContact CB-CD1 3.92Å
171	I	91.2	Very high	89.8	Confident	29 Å²	29	40.6 Å²	40.6	15%	0.149	21%	0.213	C	C	.	.	H	α-helix	trans	-58.1	-51.1	-179.9	-67.7	166.6	0	0	0	110.7	L167 Q168 I173 A175 L201 W221	L167-I171 HydrophobicContact CD1-CD1 4.09Å; L167-I171 HydrophobicContact CD1-CG1 4.22Å; L167-I171 HydrophobicContact CG-CD1 3.91Å; L167-I171 HydrophobicContact CG-CG1 4.47Å; L167-I171 WeakPolarHBondContact O-CG1 3.46Å; L167-I171 PolarHBondContact O-N 3.14Å; Q168-I171 PolarHBondContact O-N 3.43Å; I171-I173 VanDerWaalsContact C-N 3.34Å; I171-I173 PolarHBondContact O-N 3.04Å; I171-A175 WeakPolarHBondContact O-CB 3.47Å; I171-A175 PolarHBondContact O-N 3.42Å; I171-L201 HydrophobicContact CG1-CD1 3.98Å; I171-L201 HydrophobicContact CG1-CG 4.4Å; I171-W221 HydrophobicContact CG2-CB 3.65Å; I171-W221 VanDerWaalsContact CG2-CD1 3.46Å; I171-W221 HydrophobicContact CG2-CD2 4.02Å; I171-W221 HydrophobicContact CG2-CG 3.42Å; I171-W221 VanDerWaalsContact CG2-CG 3.42Å
172	H	90.6	Very high	90.4	Very high	164 Å²	164	34.4 Å²	34.4	76%	0.759	18%	0.18	S	C	*	.	H	α-helix	trans	-65.5	-36.2	-174.3	-175.7	-73.4	0	0	0	112.8	Q168 N169 L170	Q168-H172 VanDerWaalsContact O-CB 3.29Å; Q168-H172 WeakPolarHBondContact O-CB 3.33Å; Q168-H172 PolarHBondContact O-N 3.39Å; N169-H172 PolarHBondContact O-N 3.48Å; L170-H172 PolarHBondContact O-N 2.87Å
173	I	91.8	Very high	90.7	Very high	22 Å²	22	33 Å²	33	11%	0.113	18%	0.175	C	C	.	.	H	α-helix	trans	-93.9	-38.4	-173.1	-62.5	172.1	0	0	0	111.8	Q117 L120 K121 I124 N169 L170 I171	Q117-I173 HydrophobicContact CB-CD1 3.69Å; Q117-I173 HydrophobicContact CG-CD1 3.74Å; L120-I173 HydrophobicContact CB-CB 4.44Å; L120-I173 HydrophobicContact CB-CD1 4.16Å; L120-I173 HydrophobicContact CB-CG2 3.93Å; L120-I173 HydrophobicContact CD1-CD1 4.17Å; K121-I173 HydrophobicContact CG-CG2 4.23Å; I124-I173 HydrophobicContact CG1-CG2 4.29Å; N169-I173 VanDerWaalsContact O-CB 3.31Å; N169-I173 WeakPolarHBondContact O-CB 3.31Å; N169-I173 WeakPolarHBondContact O-CG1 3.3Å; N169-I173 PolarHBondContact O-N 3.43Å; L170-I173 PolarHBondContact O-N 2.9Å; I171-I173 VanDerWaalsContact C-N 3.34Å; I171-I173 PolarHBondContact O-N 3.04Å
174	T	93.9	Very high	90.6	Very high	0 Å²	0	35.2 Å²	35.2	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-108.8	-26.4	-165.6	78	0	0	0	0	113.7	L120 I124 L144 L170 G176 P177 L178	L120-T174 HydrophobicContact CD2-CG2 4.43Å; I124-T174 HydrophobicContact CD1-CG2 4.16Å; I124-T174 HydrophobicContact CG1-CG2 4.2Å; L144-T174 HydrophobicContact CD1-CG2 3.84Å; L170-T174 HydrophobicContact CD2-CG2 4.41Å; L170-T174 WeakPolarHBondContact O-CB 3.21Å; L170-T174 PolarHBondContact O-N 2.69Å; L170-T174 PolarHBondContact O-OG1 2.91Å; T174-G176 PolarHBondContact O-N 3.12Å; T174-P177 WeakPolarHBondContact O-CD 3.39Å; T174-L178 VanDerWaalsContact O-CB 3.27Å; T174-L178 WeakPolarHBondContact O-CB 3.46Å; T174-L178 WeakPolarHBondContact O-CG 3.33Å; T174-L178 PolarHBondContact O-N 3.33Å
175	A	91.9	Very high	90	Very high	2 Å²	2	33.6 Å²	33.6	2%	0.017	19%	0.187	C	C	.	.	H	α-helix	trans	-59	-47.9	-173.5	0	0	0	0	0	113.2	I171 L178 V179 L201 W221 L225	I171-A175 WeakPolarHBondContact O-CB 3.47Å; I171-A175 PolarHBondContact O-N 3.42Å; A175-L178 PolarHBondContact O-N 2.9Å; A175-V179 WeakPolarHBondContact O-CG2 3.47Å; A175-V179 PolarHBondContact O-N 2.86Å; A175-L201 HydrophobicContact CB-CD2 3.93Å; A175-W221 HydrophobicContact CB-CD2 4.33Å; A175-W221 HydrophobicContact CB-CE3 3.7Å; A175-W221 HydrophobicContact CB-CZ3 3.85Å; A175-L225 VanDerWaalsContact C-CD1 3.48Å; A175-L225 HydrophobicContact CB-CD1 3.65Å
176	G	92.4	Very high	89.6	Confident	21 Å²	21	35.5 Å²	35.5	22%	0.216	21%	0.212	C	C	.	.	H	α-helix	trans	-58.1	-58.2	177.1	0	0	0	0	0	112.7	T174 L178 V179 I180	T174-G176 PolarHBondContact O-N 3.12Å; G176-L178 VanDerWaalsContact C-N 3.29Å; G176-L178 PolarHBondContact O-N 3Å; G176-V179 PolarHBondContact O-N 3.31Å; G176-I180 WeakPolarHBondContact O-CG1 3.19Å; G176-I180 PolarHBondContact O-N 3.07Å; G176-I180 VanDerWaalsContact O-N 3.16Å
177	P	93	Very high	89.2	Confident	34 Å²	34	38.9 Å²	38.9	22%	0.221	23%	0.23	C	C	.	.	H	α-helix	trans	-53.2	-42.3	174.6	-29.4	35.4	0	0	0	113.8	I124 T174 V179 I180 F181	I124-P177 HydrophobicContact CD1-CB 3.95Å; I124-P177 HydrophobicContact CD1-CG 4.31Å; I124-P177 HydrophobicContact CG2-CB 4.15Å; I124-P177 HydrophobicContact CG2-CG 3.9Å; T174-P177 WeakPolarHBondContact O-CD 3.39Å; P177-V179 PolarHBondContact O-N 3.09Å; P177-I180 WeakPolarHBondContact O-CB 3.34Å; P177-I180 PolarHBondContact O-N 3.36Å; P177-I180 VanDerWaalsContact O-N 3.16Å; P177-F181 HydrophobicContact CB-CD2 4.43Å; P177-F181 HydrophobicContact CB-CE2 3.92Å; P177-F181 HydrophobicContact CB-CZ 4.49Å; P177-F181 WeakPolarHBondContact O-CD2 3.31Å; P177-F181 VanDerWaalsContact O-CG 3.27Å; P177-F181 WeakPolarHBondContact O-CG 3.27Å; P177-F181 PolarHBondContact O-N 3.26Å
178	L	94.6	Very high	88.8	Confident	0 Å²	0	40.2 Å²	40.2	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-63.1	-38.7	179.3	-73.8	175.6	0	0	0	112.8	M141 L144 T174 A175 G176 I180 F181 S182 A197 L198	M141-L178 HydrophobicContact CE-CD2 3.64Å; L144-L178 HydrophobicContact CD2-CD2 3.94Å; L144-L178 HydrophobicContact CD2-CG 4.49Å; T174-L178 VanDerWaalsContact O-CB 3.27Å; T174-L178 WeakPolarHBondContact O-CB 3.46Å; T174-L178 WeakPolarHBondContact O-CG 3.33Å; T174-L178 PolarHBondContact O-N 3.33Å; A175-L178 PolarHBondContact O-N 2.9Å; G176-L178 VanDerWaalsContact C-N 3.29Å; G176-L178 PolarHBondContact O-N 3Å; L178-I180 VanDerWaalsContact C-N 3.33Å; L178-F181 PolarHBondContact O-N 3.09Å; L178-S182 WeakPolarHBondContact O-CB 3.22Å; L178-S182 PolarHBondContact O-N 3.27Å; L178-S182 PolarHBondContact O-OG 2.88Å; L178-A197 HydrophobicContact CD1-CB 3.94Å; L178-A197 HydrophobicContact CD2-CB 3.79Å; L178-L198 HydrophobicContact CB-CD1 4.47Å; L178-L198 HydrophobicContact CB-CD2 3.62Å; L178-L198 HydrophobicContact CB-CG 3.86Å; L178-L198 HydrophobicContact CD1-CD2 4.32Å
179	V	92.4	Very high	88.6	Confident	4 Å²	4	37.8 Å²	37.8	2%	0.024	23%	0.232	C	C	.	.	H	α-helix	trans	-65.2	-37.2	173.8	172.8	0	0	0	0	111.6	A175 G176 P177 S182 S183 L198 L225 L227 H230	A175-V179 WeakPolarHBondContact O-CG2 3.47Å; A175-V179 PolarHBondContact O-N 2.86Å; G176-V179 PolarHBondContact O-N 3.31Å; P177-V179 PolarHBondContact O-N 3.09Å; V179-S182 WeakPolarHBondContact CA-OG 3.26Å; V179-S182 PolarHBondContact O-OG 3.45Å; V179-S182 VanDerWaalsContact O-OG 3.11Å; V179-S183 WeakPolarHBondContact O-CB 3.45Å; V179-S183 PolarHBondContact O-N 3.39Å; V179-S183 PolarHBondContact O-OG 3.16Å; V179-L198 HydrophobicContact CG2-CD1 4.23Å; V179-L198 HydrophobicContact CG2-CD2 4Å; V179-L225 HydrophobicContact CG2-CB 4.34Å; V179-L225 HydrophobicContact CG2-CD1 4.07Å; V179-L227 HydrophobicContact CG2-CD1 3.77Å; V179-H230 HydrophobicContact CG1-CB 4.15Å
180	I	90.4	Very high	88.3	Confident	106 Å²	106	37.3 Å²	37.3	54%	0.544	23%	0.23	S	C	.	.	H	α-helix	trans	-67.6	-44.4	176.7	-64.3	168	0	0	0	110.6	G176 P177 L178 S183 S184	G176-I180 WeakPolarHBondContact O-CG1 3.19Å; G176-I180 PolarHBondContact O-N 3.07Å; G176-I180 VanDerWaalsContact O-N 3.16Å; P177-I180 WeakPolarHBondContact O-CB 3.34Å; P177-I180 PolarHBondContact O-N 3.36Å; P177-I180 VanDerWaalsContact O-N 3.16Å; L178-I180 VanDerWaalsContact C-N 3.33Å; I180-S183 PolarHBondContact O-N 3.15Å; I180-S183 PolarHBondContact O-OG 2.99Å; I180-S184 PolarHBondContact O-N 2.84Å; I180-S184 PolarHBondContact O-OG 3.42Å
181	F	91.9	Very high	88.1	Confident	25 Å²	25	37.3 Å²	37.3	11%	0.11	23%	0.23	C	C	.	.	H	α-helix	trans	-67.5	-39.4	178.5	-61.7	-39.1	0	0	0	112.4	I127 P128 P177 L178 S183 S184 L187 I190	I127-F181 HydrophobicContact CB-CE2 4.33Å; I127-F181 HydrophobicContact CB-CZ 4.46Å; I127-F181 HydrophobicContact CG2-CD2 4.1Å; I127-F181 HydrophobicContact CG2-CE1 4.38Å; I127-F181 HydrophobicContact CG2-CE2 3.62Å; I127-F181 HydrophobicContact CG2-CZ 3.79Å; P128-F181 HydrophobicContact CB-CE1 4.33Å; P128-F181 HydrophobicContact CB-CZ 4.3Å; P128-F181 HydrophobicContact CG-CZ 4.41Å; P177-F181 HydrophobicContact CB-CD2 4.43Å; P177-F181 HydrophobicContact CB-CE2 3.92Å; P177-F181 HydrophobicContact CB-CZ 4.49Å; P177-F181 WeakPolarHBondContact O-CD2 3.31Å; P177-F181 VanDerWaalsContact O-CG 3.27Å; P177-F181 WeakPolarHBondContact O-CG 3.27Å; P177-F181 PolarHBondContact O-N 3.26Å; L178-F181 PolarHBondContact O-N 3.09Å; F181-S183 VanDerWaalsContact C-N 3.33Å; F181-S183 PolarHBondContact O-N 2.98Å; F181-S184 PolarHBondContact O-N 3.47Å; F181-L187 HydrophobicContact CB-CD1 4.38Å; F181-L187 HydrophobicContact CD1-CD1 3.97Å; F181-I190 HydrophobicContact CB-CG2 4.35Å
182	S	91	Very high	87.9	Confident	4 Å²	4	36.3 Å²	36.3	3%	0.028	23%	0.225	C	C	.	.	H	α-helix	trans	-69.8	-31.6	177.8	67.3	0	0	0	0	112.4	L178 V179 S184 T191 S194 T195 L198 H278	L178-S182 WeakPolarHBondContact O-CB 3.22Å; L178-S182 PolarHBondContact O-N 3.27Å; L178-S182 PolarHBondContact O-OG 2.88Å; V179-S182 WeakPolarHBondContact CA-OG 3.26Å; V179-S182 PolarHBondContact O-OG 3.45Å; V179-S182 VanDerWaalsContact O-OG 3.11Å; S182-S184 PolarHBondContact O-N 3.24Å; S182-T191 VanDerWaalsContact O-CG2 3.28Å; S182-T191 WeakPolarHBondContact O-CG2 3.42Å; S182-S194 WeakPolarHBondContact CA-OG 3.41Å; S182-S194 PolarHBondContact N-OG 2.92Å; S182-T195 WeakPolarHBondContact CB-OG1 3.21Å; S182-L198 WeakPolarHBondContact OG-CD1 3.27Å; S182-H278 PolarHBondContact O-NE2 3.36Å
183	S	88	Confident	87.9	Confident	31 Å²	31	30.1 Å²	30.1	22%	0.217	19%	0.194	C	C	.	.	H	α-helix	trans	-75.5	-11.8	176.9	57.7	0	0	0	0	114.8	V179 I180 F181 S185	V179-S183 WeakPolarHBondContact O-CB 3.45Å; V179-S183 PolarHBondContact O-N 3.39Å; V179-S183 PolarHBondContact O-OG 3.16Å; I180-S183 PolarHBondContact O-N 3.15Å; I180-S183 PolarHBondContact O-OG 2.99Å; F181-S183 VanDerWaalsContact C-N 3.33Å; F181-S183 PolarHBondContact O-N 2.98Å; S183-S185 PolarHBondContact O-N 3.36Å
184	S	85.2	Confident	88	Confident	46 Å²	46	29 Å²	29	32%	0.322	19%	0.189	S	C	.	.			trans	-97.6	84.8	-178.9	-60.6	0	0	0	0	110.7	I180 F181 S182 G186 L187 T191	I180-S184 PolarHBondContact O-N 2.84Å; I180-S184 PolarHBondContact O-OG 3.42Å; F181-S184 PolarHBondContact O-N 3.47Å; S182-S184 PolarHBondContact O-N 3.24Å; S184-G186 PolarHBondContact O-N 2.94Å; S184-L187 PolarHBondContact O-N 2.8Å; S184-L187 VanDerWaalsContact O-N 3.08Å; S184-T191 PolarHBondContact O-OG1 3.35Å
185	S	72	Confident	87.9	Confident	38 Å²	38	29 Å²	29	27%	0.266	19%	0.189	S	C	.	.	G	3₁₀ helix	trans	-59.1	-20.5	-178.5	64.5	0	0	0	0	114.5	S183 L187	S183-S185 PolarHBondContact O-N 3.36Å; S185-L187 VanDerWaalsContact C-N 3.26Å; S185-L187 PolarHBondContact O-N 3.07Å
186	G	77	Confident	87.9	Confident	77 Å²	77	32.6 Å²	32.6	79%	0.794	21%	0.205	S	C	*	.	G	3₁₀ helix	trans	-74.3	-7.8	177.1	0	0	0	0	0	115.1	S184 G188	S184-G186 PolarHBondContact O-N 2.94Å; G186-G188 VanDerWaalsContact C-N 3.26Å; G186-G188 PolarHBondContact O-N 3.42Å
187	L	80.8	Confident	88	Confident	72 Å²	72	31.6 Å²	31.6	38%	0.377	20%	0.195	S	C	.	.	G	3₁₀ helix	trans	-85.3	3.7	178.7	-57.4	176.7	0	0	0	113.3	F181 S184 S185 Q189 I190 T191	F181-L187 HydrophobicContact CB-CD1 4.38Å; F181-L187 HydrophobicContact CD1-CD1 3.97Å; S184-L187 PolarHBondContact O-N 2.8Å; S184-L187 VanDerWaalsContact O-N 3.08Å; S185-L187 VanDerWaalsContact C-N 3.26Å; S185-L187 PolarHBondContact O-N 3.07Å; L187-Q189 PolarHBondContact O-N 3.02Å; L187-Q189 VanDerWaalsContact O-N 3.11Å; L187-I190 HydrophobicContact CB-CB 4.03Å; L187-I190 HydrophobicContact CB-CG2 4.39Å; L187-I190 HydrophobicContact CD1-CG2 4.3Å; L187-I190 PolarHBondContact O-N 3.01Å; L187-T191 WeakPolarHBondContact CB-OG1 3.34Å
188	G	82.8	Confident	88	Confident	27 Å²	27	30 Å²	30	28%	0.278	18%	0.184	S	C	.	.	T	Hydrogen-bonded Turn	trans	55.6	-115.1	174.6	0	0	0	0	0	112.7	G186 I190 T191 I192	G186-G188 VanDerWaalsContact C-N 3.26Å; G186-G188 PolarHBondContact O-N 3.42Å; G188-I190 VanDerWaalsContact C-N 3.3Å; G188-I190 PolarHBondContact O-N 3.08Å; G188-T191 PolarHBondContact N-OG1 3.49Å; G188-T191 VanDerWaalsContact O-CB 3.26Å; G188-T191 WeakPolarHBondContact O-CB 3.26Å; G188-T191 PolarHBondContact O-N 3Å; G188-T191 VanDerWaalsContact O-N 3.16Å; G188-T191 PolarHBondContact O-OG1 3.43Å; G188-I192 PolarHBondContact O-N 3.21Å
189	Q	84.6	Confident	87.9	Confident	64 Å²	64	31.3 Å²	31.3	30%	0.299	19%	0.193	S	C	.	.	H	α-helix	trans	-65.8	-30.5	-175.1	-166.5	61.6	36.4	0	0	113.4	L187 T191 I192 W193	L187-Q189 PolarHBondContact O-N 3.02Å; L187-Q189 VanDerWaalsContact O-N 3.11Å; Q189-T191 VanDerWaalsContact C-N 3.29Å; Q189-T191 PolarHBondContact O-N 3.28Å; Q189-I192 WeakPolarHBondContact O-CB 3.46Å; Q189-I192 PolarHBondContact O-N 3.03Å; Q189-W193 HydrophobicContact CB-CE3 4.35Å; Q189-W193 HydrophobicContact CB-CH2 4.08Å; Q189-W193 HydrophobicContact CB-CZ2 4.44Å; Q189-W193 HydrophobicContact CB-CZ3 4.01Å; Q189-W193 HydrophobicContact CG-CD2 3.77Å; Q189-W193 VanDerWaalsContact CG-CE2 3.44Å; Q189-W193 HydrophobicContact CG-CE3 3.81Å; Q189-W193 HydrophobicContact CG-CH2 3.25Å; Q189-W193 HydrophobicContact CG-CZ2 3.2Å; Q189-W193 HydrophobicContact CG-CZ3 3.55Å; Q189-W193 PolarHBondContact O-N 3.36Å
190	I	86.5	Confident	87.8	Confident	17 Å²	17	31.2 Å²	31.2	9%	0.087	19%	0.193	C	C	.	.	H	α-helix	trans	-64.1	-36.8	175.6	-63.7	172.8	0	0	0	110.6	I127 Q137 M141 F181 L187 G188 I192 W193 S194	I127-I190 HydrophobicContact CG2-CG2 4.34Å; Q137-I190 HydrophobicContact CB-CD1 4.38Å; M141-I190 HydrophobicContact CG-CG2 4.31Å; M141-I190 HydrophobicContact SD-CG2 4.27Å; F181-I190 HydrophobicContact CB-CG2 4.35Å; L187-I190 HydrophobicContact CB-CB 4.03Å; L187-I190 HydrophobicContact CB-CG2 4.39Å; L187-I190 HydrophobicContact CD1-CG2 4.3Å; L187-I190 PolarHBondContact O-N 3.01Å; G188-I190 VanDerWaalsContact C-N 3.3Å; G188-I190 PolarHBondContact O-N 3.08Å; I190-I192 VanDerWaalsContact C-N 3.32Å; I190-I192 PolarHBondContact O-N 3.5Å; I190-W193 HydrophobicContact CG1-CE3 4.42Å; I190-W193 HydrophobicContact CG1-CZ3 4.49Å; I190-W193 PolarHBondContact O-N 3.33Å; I190-S194 VanDerWaalsContact O-CB 3.29Å; I190-S194 WeakPolarHBondContact O-CB 3.46Å; I190-S194 PolarHBondContact O-N 3.06Å; I190-S194 PolarHBondContact O-OG 3.22Å
191	T	88.7	Confident	87.9	Confident	0 Å²	0	26.2 Å²	26.2	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-60.5	-42.8	174.4	-46.7	0	0	0	0	111	S182 S184 L187 G188 Q189 S194 T195 I274	S182-T191 VanDerWaalsContact O-CG2 3.28Å; S182-T191 WeakPolarHBondContact O-CG2 3.42Å; S184-T191 PolarHBondContact O-OG1 3.35Å; L187-T191 WeakPolarHBondContact CB-OG1 3.34Å; G188-T191 PolarHBondContact N-OG1 3.49Å; G188-T191 VanDerWaalsContact O-CB 3.26Å; G188-T191 WeakPolarHBondContact O-CB 3.26Å; G188-T191 PolarHBondContact O-N 3Å; G188-T191 VanDerWaalsContact O-N 3.16Å; G188-T191 PolarHBondContact O-OG1 3.43Å; Q189-T191 VanDerWaalsContact C-N 3.29Å; Q189-T191 PolarHBondContact O-N 3.28Å; T191-S194 WeakPolarHBondContact CA-OG 3.12Å; T191-S194 PolarHBondContact O-OG 3.45Å; T191-T195 WeakPolarHBondContact O-CB 3.46Å; T191-T195 PolarHBondContact O-N 3.24Å; T191-T195 PolarHBondContact O-OG1 3.36Å; T191-I274 HydrophobicContact CG2-CD1 4.32Å; T191-I274 HydrophobicContact CG2-CG1 4.46Å; T191-I274 HydrophobicContact CG2-CG2 4.06Å
192	I	87	Confident	87.8	Confident	9 Å²	9	25 Å²	25	5%	0.046	16%	0.162	C	C	.	.	H	α-helix	trans	-65.5	-51	179.4	-61.6	164	0	0	0	110.2	G188 Q189 I190 S194 T195 Q196 D273 I274	G188-I192 PolarHBondContact O-N 3.21Å; Q189-I192 WeakPolarHBondContact O-CB 3.46Å; Q189-I192 PolarHBondContact O-N 3.03Å; I190-I192 VanDerWaalsContact C-N 3.32Å; I190-I192 PolarHBondContact O-N 3.5Å; I192-S194 PolarHBondContact O-N 3.45Å; I192-T195 PolarHBondContact O-N 3.36Å; I192-Q196 WeakPolarHBondContact O-CG 3.37Å; I192-Q196 PolarHBondContact O-N 3.23Å; I192-D273 HydrophobicContact CD1-CB 3.47Å; I192-D273 VanDerWaalsContact CD1-CB 3.47Å; I192-D273 HydrophobicContact CG1-CB 4.2Å; I192-I274 HydrophobicContact CD1-CG1 4.13Å; I192-I274 HydrophobicContact CG1-CG1 3.63Å
193	W	91.1	Very high	87.7	Confident	33 Å²	33	26.6 Å²	26.6	13%	0.125	17%	0.17	C	C	.	.	H	α-helix	trans	-63.7	-40.6	-179.4	-68.6	-38.1	0	0	0	112.4	E138 M141 I142 T145 Q189 I190 T195 Q196 A197	E138-W193 HydrophobicContact CB-CH2 3.66Å; E138-W193 HydrophobicContact CB-CZ3 3.7Å; E138-W193 HydrophobicContact CG-CH2 3.75Å; E138-W193 HydrophobicContact CG-CZ3 3.71Å; M141-W193 HydrophobicContact CB-CE3 3.93Å; M141-W193 HydrophobicContact CE-CB 4.13Å; M141-W193 HydrophobicContact CG-CB 3.57Å; M141-W193 HydrophobicContact CG-CD2 4.32Å; M141-W193 HydrophobicContact CG-CE3 3.79Å; M141-W193 HydrophobicContact CG-CG 4.32Å; I142-W193 HydrophobicContact CD1-CH2 4Å; I142-W193 HydrophobicContact CD1-CZ2 3.69Å; I142-W193 HydrophobicContact CG1-CD2 4.11Å; I142-W193 HydrophobicContact CG1-CE3 4.47Å; I142-W193 HydrophobicContact CG1-CH2 4.1Å; I142-W193 HydrophobicContact CG1-CZ2 3.67Å; I142-W193 HydrophobicContact CG1-CZ3 4.49Å; T145-W193 WeakPolarHBondContact OG1-CB 3.49Å; T145-W193 PolarHBondContact OG1-O 2.89Å; Q189-W193 HydrophobicContact CB-CE3 4.35Å; Q189-W193 HydrophobicContact CB-CH2 4.08Å; Q189-W193 HydrophobicContact CB-CZ2 4.44Å; Q189-W193 HydrophobicContact CB-CZ3 4.01Å; Q189-W193 HydrophobicContact CG-CD2 3.77Å; Q189-W193 VanDerWaalsContact CG-CE2 3.44Å; Q189-W193 HydrophobicContact CG-CE3 3.81Å; Q189-W193 HydrophobicContact CG-CH2 3.25Å; Q189-W193 HydrophobicContact CG-CZ2 3.2Å; Q189-W193 HydrophobicContact CG-CZ3 3.55Å; Q189-W193 PolarHBondContact O-N 3.36Å; I190-W193 HydrophobicContact CG1-CE3 4.42Å; I190-W193 HydrophobicContact CG1-CZ3 4.49Å; I190-W193 PolarHBondContact O-N 3.33Å; W193-T195 VanDerWaalsContact C-N 3.34Å; W193-T195 PolarHBondContact O-N 2.76Å; W193-Q196 PolarHBondContact O-N 3.12Å; W193-A197 WeakPolarHBondContact O-CB 3.42Å; W193-A197 PolarHBondContact O-N 3.44Å
194	S	93.3	Very high	87.7	Confident	0 Å²	0	25.1 Å²	25.1	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-64.2	-38.7	176	54	0	0	0	0	112.3	S182 I190 T191 I192 A197 L198	S182-S194 WeakPolarHBondContact CA-OG 3.41Å; S182-S194 PolarHBondContact N-OG 2.92Å; I190-S194 VanDerWaalsContact O-CB 3.29Å; I190-S194 WeakPolarHBondContact O-CB 3.46Å; I190-S194 PolarHBondContact O-N 3.06Å; I190-S194 PolarHBondContact O-OG 3.22Å; T191-S194 WeakPolarHBondContact CA-OG 3.12Å; T191-S194 PolarHBondContact O-OG 3.45Å; I192-S194 PolarHBondContact O-N 3.45Å; S194-A197 WeakPolarHBondContact O-CB 3.24Å; S194-A197 PolarHBondContact O-N 2.96Å; S194-L198 WeakPolarHBondContact O-CG 3.42Å; S194-L198 PolarHBondContact O-N 2.99Å
195	T	92	Very high	87.8	Confident	0 Å²	0	22.9 Å²	22.9	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-65.3	-39.2	174.3	-53.5	0	0	0	0	112	S182 T191 I192 W193 L198 T199 S277 H278 L281	S182-T195 WeakPolarHBondContact CB-OG1 3.21Å; T191-T195 WeakPolarHBondContact O-CB 3.46Å; T191-T195 PolarHBondContact O-N 3.24Å; T191-T195 PolarHBondContact O-OG1 3.36Å; I192-T195 PolarHBondContact O-N 3.36Å; W193-T195 VanDerWaalsContact C-N 3.34Å; W193-T195 PolarHBondContact O-N 2.76Å; T195-L198 PolarHBondContact O-N 3.45Å; T195-T199 PolarHBondContact O-N 3.21Å; T195-T199 PolarHBondContact O-OG1 3.06Å; T195-S277 VanDerWaalsContact CG2-C 3.48Å; T195-S277 VanDerWaalsContact CG2-O 3.32Å; T195-S277 WeakPolarHBondContact CG2-O 3.46Å; T195-H278 PolarHBondContact OG1-CE1 3.45Å; T195-L281 HydrophobicContact CG2-CB 3.98Å; T195-L281 HydrophobicContact CG2-CD2 3.77Å; T195-L281 HydrophobicContact CG2-CG 4.5Å
196	Q	91.6	Very high	88.5	Confident	76 Å²	76	21.9 Å²	21.9	36%	0.355	14%	0.135	S	C	.	.	H	α-helix	trans	-68.2	-38.2	173.6	-71.2	175.3	-7.5	0	0	112.2	T145 I149 I192 W193 T199 G200	T145-Q196 HydrophobicContact CG2-CB 3.84Å; I149-Q196 HydrophobicContact CD1-CB 4.45Å; I192-Q196 WeakPolarHBondContact O-CG 3.37Å; I192-Q196 PolarHBondContact O-N 3.23Å; W193-Q196 PolarHBondContact O-N 3.12Å; Q196-T199 WeakPolarHBondContact O-CB 3.38Å; Q196-T199 PolarHBondContact O-N 2.79Å; Q196-G200 PolarHBondContact O-N 3.25Å
197	A	93.3	Very high	88.8	Confident	0 Å²	0	20.1 Å²	20.1	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-63.8	-44.3	174.6	0	0	0	0	0	110.8	M141 T145 C148 L178 W193 S194 T199 G200 L201	M141-A197 HydrophobicContact CE-CB 4.13Å; T145-A197 HydrophobicContact CG2-CB 4.33Å; C148-A197 HydrophobicContact CB-CB 4.15Å; C148-A197 VanDerWaalsContact CB-O 3.25Å; C148-A197 WeakPolarHBondContact CB-O 3.4Å; L178-A197 HydrophobicContact CD1-CB 3.94Å; L178-A197 HydrophobicContact CD2-CB 3.79Å; W193-A197 WeakPolarHBondContact O-CB 3.42Å; W193-A197 PolarHBondContact O-N 3.44Å; S194-A197 WeakPolarHBondContact O-CB 3.24Å; S194-A197 PolarHBondContact O-N 2.96Å; A197-T199 VanDerWaalsContact C-N 3.31Å; A197-T199 PolarHBondContact O-N 3.25Å; A197-G200 PolarHBondContact O-N 3.35Å; A197-L201 WeakPolarHBondContact O-CB 3.24Å; A197-L201 PolarHBondContact O-N 3.44Å
198	L	94.6	Very high	88.9	Confident	0 Å²	0	17.3 Å²	17.3	0%	0	9%	0.092	C	C	.	.	H	α-helix	trans	-58.6	-43.3	172.5	-73.4	171.8	0	0	0	111.6	L178 V179 S182 S194 T195 G200 L201 L202 L227 L281	L178-L198 HydrophobicContact CB-CD1 4.47Å; L178-L198 HydrophobicContact CB-CD2 3.62Å; L178-L198 HydrophobicContact CB-CG 3.86Å; L178-L198 HydrophobicContact CD1-CD2 4.32Å; V179-L198 HydrophobicContact CG2-CD1 4.23Å; V179-L198 HydrophobicContact CG2-CD2 4Å; S182-L198 WeakPolarHBondContact OG-CD1 3.27Å; S194-L198 WeakPolarHBondContact O-CG 3.42Å; S194-L198 PolarHBondContact O-N 2.99Å; T195-L198 PolarHBondContact O-N 3.45Å; L198-G200 PolarHBondContact O-N 3.49Å; L198-L201 PolarHBondContact O-N 3.24Å; L198-L202 WeakPolarHBondContact O-CB 3.32Å; L198-L202 VanDerWaalsContact O-CG 3.3Å; L198-L202 WeakPolarHBondContact O-CG 2.88Å; L198-L202 PolarHBondContact O-N 3.46Å; L198-L227 HydrophobicContact CD1-CD1 4.17Å; L198-L281 HydrophobicContact CB-CD1 4.25Å; L198-L281 HydrophobicContact CB-CD2 4.2Å; L198-L281 HydrophobicContact CD1-CD2 4.15Å
199	T	91.4	Very high	88.8	Confident	28 Å²	28	18.2 Å²	18.2	17%	0.172	9%	0.087	C	C	.	.	H	α-helix	trans	-58.1	-46.7	175.1	-65.4	0	0	0	0	111.8	T195 Q196 A197 N203 I284	T195-T199 PolarHBondContact O-N 3.21Å; T195-T199 PolarHBondContact O-OG1 3.06Å; Q196-T199 WeakPolarHBondContact O-CB 3.38Å; Q196-T199 PolarHBondContact O-N 2.79Å; A197-T199 VanDerWaalsContact C-N 3.31Å; A197-T199 PolarHBondContact O-N 3.25Å; T199-N203 PolarHBondContact O-N 3.07Å; T199-N203 PolarHBondContact O-ND2 3.15Å; T199-I284 HydrophobicContact CG2-CD1 3.36Å
200	G	90.3	Very high	88.3	Confident	3 Å²	3	18.8 Å²	18.8	3%	0.031	10%	0.096	C	C	.	.	H	α-helix	trans	-61.3	-45.8	175	0	0	0	0	0	112.6	C148 G152 Q196 A197 L198 L202 N203 A204	C148-G200 CarbonylContact O-C 3.56Å; C148-G200 VanDerWaalsContact O-CA 3.27Å; C148-G200 WeakPolarHBondContact O-CA 3.42Å; G152-G200 WeakPolarHBondContact CA-O 3.34Å; Q196-G200 PolarHBondContact O-N 3.25Å; A197-G200 PolarHBondContact O-N 3.35Å; L198-G200 PolarHBondContact O-N 3.49Å; G200-L202 PolarHBondContact O-N 3.44Å; G200-N203 PolarHBondContact O-N 2.68Å; G200-A204 WeakPolarHBondContact O-CB 3.49Å; G200-A204 PolarHBondContact O-N 2.87Å
201	L	92.3	Very high	87.5	Confident	0 Å²	0	22.9 Å²	22.9	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-64.3	-39.3	179.8	-171.9	64.5	0	0	0	112.5	L167 L170 I171 A175 A197 L198 A204 T205 W221	L167-L201 HydrophobicContact CD1-CD1 3.9Å; L170-L201 HydrophobicContact CB-CD1 3.92Å; I171-L201 HydrophobicContact CG1-CD1 3.98Å; I171-L201 HydrophobicContact CG1-CG 4.4Å; A175-L201 HydrophobicContact CB-CD2 3.93Å; A197-L201 WeakPolarHBondContact O-CB 3.24Å; A197-L201 PolarHBondContact O-N 3.44Å; L198-L201 PolarHBondContact O-N 3.24Å; L201-A204 PolarHBondContact O-N 2.92Å; L201-T205 WeakPolarHBondContact O-CB 3.49Å; L201-T205 PolarHBondContact O-N 2.72Å; L201-T205 PolarHBondContact O-OG1 3.28Å; L201-W221 HydrophobicContact CD2-CH2 3.95Å; L201-W221 HydrophobicContact CD2-CZ2 4.05Å; L201-W221 HydrophobicContact CG-CH2 4.28Å; L201-W221 HydrophobicContact CG-CZ2 4.02Å
202	L	90.4	Very high	86.4	Confident	0 Å²	0	23.7 Å²	23.7	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-61.5	-51.3	172.3	-76.9	-178.1	0	0	0	111.1	L198 G200 A204 T205 F206 W221 M222 L227 L281 I284 I285	L198-L202 WeakPolarHBondContact O-CB 3.32Å; L198-L202 VanDerWaalsContact O-CG 3.3Å; L198-L202 WeakPolarHBondContact O-CG 2.88Å; L198-L202 PolarHBondContact O-N 3.46Å; G200-L202 PolarHBondContact O-N 3.44Å; L202-A204 VanDerWaalsContact C-N 3.26Å; L202-A204 PolarHBondContact O-N 2.91Å; L202-T205 WeakPolarHBondContact O-CB 3.47Å; L202-T205 PolarHBondContact O-N 3.42Å; L202-T205 VanDerWaalsContact O-N 3.13Å; L202-F206 HydrophobicContact CB-CD2 4.47Å; L202-F206 HydrophobicContact CB-CE2 4.1Å; L202-F206 HydrophobicContact CD2-CE2 4.37Å; L202-F206 WeakPolarHBondContact O-CD2 3.29Å; L202-F206 WeakPolarHBondContact O-CG 3.35Å; L202-F206 PolarHBondContact O-N 2.85Å; L202-W221 HydrophobicContact CD2-CH2 3.83Å; L202-W221 HydrophobicContact CD2-CZ2 3.81Å; L202-W221 HydrophobicContact CG-CH2 4.37Å; L202-M222 HydrophobicContact CD2-CG 3.68Å; L202-M222 HydrophobicContact CD2-SD 3.08Å; L202-M222 WeakPolarHBondContact CD2-SD 3.42Å; L202-L227 HydrophobicContact CD1-CD2 4.08Å; L202-L227 HydrophobicContact CD2-CD2 3.81Å; L202-L227 HydrophobicContact CG-CD2 4.27Å; L202-L281 HydrophobicContact CD1-CD1 3.36Å; L202-L281 HydrophobicContact CG-CD1 4.47Å; L202-I284 HydrophobicContact CB-CG2 4.3Å; L202-I284 HydrophobicContact CD1-CG2 4.09Å; L202-I285 HydrophobicContact CD1-CG1 3.87Å
203	N	89.1	Confident	84.8	Confident	37 Å²	37	26 Å²	26	20%	0.198	14%	0.138	C	C	.	.	H	α-helix	trans	-58.7	-41.1	178.4	-77	-33.6	0	0	0	111.7	T199 G200 F206 I207 R288	T199-N203 PolarHBondContact O-N 3.07Å; T199-N203 PolarHBondContact O-ND2 3.15Å; G200-N203 PolarHBondContact O-N 2.68Å; N203-F206 PolarHBondContact O-N 3.39Å; N203-I207 VanDerWaalsContact O-CG1 3.26Å; N203-I207 WeakPolarHBondContact O-CG1 3.43Å; N203-I207 PolarHBondContact O-N 3.2Å; N203-R288 PolarHBondContact OD1-NH1 3.05Å
204	A	88.3	Confident	82.9	Confident	0 Å²	0	29.7 Å²	29.7	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-60.8	-50.5	174.5	0	0	0	0	0	110.5	A151 L167 G200 L201 L202 F206 I207 Y208	A151-A204 HydrophobicContact CB-CB 3.79Å; A151-A204 WeakPolarHBondContact O-CB 3.38Å; L167-A204 HydrophobicContact CD1-CB 3.79Å; G200-A204 WeakPolarHBondContact O-CB 3.49Å; G200-A204 PolarHBondContact O-N 2.87Å; L201-A204 PolarHBondContact O-N 2.92Å; L202-A204 VanDerWaalsContact C-N 3.26Å; L202-A204 PolarHBondContact O-N 2.91Å; A204-F206 VanDerWaalsContact C-N 3.29Å; A204-F206 PolarHBondContact O-N 2.84Å; A204-I207 PolarHBondContact O-N 3.45Å; A204-Y208 HydrophobicContact CB-CD2 4.49Å; A204-Y208 WeakPolarHBondContact O-CD2 3.26Å; A204-Y208 PolarHBondContact O-N 2.75Å
205	T	87.9	Confident	80.9	Confident	0 Å²	0	33.9 Å²	33.9	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-52.2	-48	177.7	-58.2	0	0	0	0	111.3	L201 L202 I207 Y208 Y209 L212 W221 M222	L201-T205 WeakPolarHBondContact O-CB 3.49Å; L201-T205 PolarHBondContact O-N 2.72Å; L201-T205 PolarHBondContact O-OG1 3.28Å; L202-T205 WeakPolarHBondContact O-CB 3.47Å; L202-T205 PolarHBondContact O-N 3.42Å; L202-T205 VanDerWaalsContact O-N 3.13Å; T205-I207 VanDerWaalsContact C-N 3.33Å; T205-I207 PolarHBondContact O-N 3.01Å; T205-Y208 PolarHBondContact O-N 2.69Å; T205-Y209 HydrophobicContact CG2-CD2 4.31Å; T205-Y209 WeakPolarHBondContact O-CA 3.45Å; T205-Y209 WeakPolarHBondContact O-CB 3.27Å; T205-Y209 PolarHBondContact O-N 2.93Å; T205-L212 HydrophobicContact CG2-CD1 3.51Å; T205-W221 PolarHBondContact OG1-NE1 3.25Å; T205-M222 HydrophobicContact CG2-CE 4.08Å
206	F	85.6	Confident	78.9	Confident	16 Å²	16	39.5 Å²	39.5	7%	0.07	21%	0.209	C	C	.	.	H	α-helix	trans	-69.9	-23.8	178.9	-62.8	-54	0	0	0	114.5	L202 N203 A204 M222 I284 R288 L289	L202-F206 HydrophobicContact CB-CD2 4.47Å; L202-F206 HydrophobicContact CB-CE2 4.1Å; L202-F206 HydrophobicContact CD2-CE2 4.37Å; L202-F206 WeakPolarHBondContact O-CD2 3.29Å; L202-F206 WeakPolarHBondContact O-CG 3.35Å; L202-F206 PolarHBondContact O-N 2.85Å; N203-F206 PolarHBondContact O-N 3.39Å; A204-F206 VanDerWaalsContact C-N 3.29Å; A204-F206 PolarHBondContact O-N 2.84Å; F206-M222 HydrophobicContact CE1-CE 4.21Å; F206-M222 HydrophobicContact CZ-CE 4.31Å; F206-M222 HydrophobicContact CZ-SD 4.1Å; F206-I284 HydrophobicContact CE2-CG2 4.21Å; F206-R288 HydrophobicContact CD1-CB 4.16Å; F206-R288 HydrophobicContact CD2-CB 3.89Å; F206-R288 HydrophobicContact CD2-CG 4.27Å; F206-R288 HydrophobicContact CE1-CB 3.78Å; F206-R288 WeakPolarHBondContact CE1-O 3.33Å; F206-R288 HydrophobicContact CE2-CB 3.48Å; F206-R288 VanDerWaalsContact CE2-CB 3.48Å; F206-R288 HydrophobicContact CE2-CG 4.24Å; F206-R288 HydrophobicContact CG-CB 4.22Å; F206-R288 HydrophobicContact CZ-CB 3.43Å; F206-R288 VanDerWaalsContact CZ-CB 3.43Å; F206-L289 HydrophobicContact CZ-CD1 4.41Å
207	I	83.7	Confident	76.8	Confident	41 Å²	41	45 Å²	45	21%	0.21	24%	0.235	C	C	.	.	H	α-helix	trans	-76.4	-46.1	175.5	-73.3	166.9	0	0	0	110.9	G152 K154 N203 A204 T205	G152-I207 WeakPolarHBondContact O-CD1 3.36Å; K154-I207 HydrophobicContact CG-CD1 4.03Å; K154-I207 HydrophobicContact CG-CG1 4.41Å; N203-I207 VanDerWaalsContact O-CG1 3.26Å; N203-I207 WeakPolarHBondContact O-CG1 3.43Å; N203-I207 PolarHBondContact O-N 3.2Å; A204-I207 PolarHBondContact O-N 3.45Å; T205-I207 VanDerWaalsContact C-N 3.33Å; T205-I207 PolarHBondContact O-N 3.01Å
208	Y	82.4	Confident	74.8	Confident	13 Å²	13	49.9 Å²	49.9	5%	0.051	26%	0.257	C	S	.	.	H	α-helix	trans	-88.4	-21	-173.3	-68.4	-80.6	0	0	0	113.5	W110 S158 C163 Q164 L167 A204 T205 P210	W110-Y208 HydrophobicContact CH2-CE2 4.43Å; W110-Y208 HydrophobicContact CZ2-CE2 4.16Å; W110-Y208 AromaticContact CZ2-CZ 3.92Å; W110-Y208 WeakPolarHBondContact CZ2-OH 3.37Å; S158-Y208 WeakPolarHBondContact O-CD1 3.4Å; S158-Y208 WeakPolarHBondContact O-CE1 3.48Å; C163-Y208 HydrophobicContact CB-CD1 4.33Å; C163-Y208 HydrophobicContact CB-CE1 3.54Å; Q164-Y208 HydrophobicContact CG-CD1 4.44Å; L167-Y208 HydrophobicContact CD2-CD2 3.71Å; L167-Y208 HydrophobicContact CD2-CG 3.93Å; A204-Y208 HydrophobicContact CB-CD2 4.49Å; A204-Y208 WeakPolarHBondContact O-CD2 3.26Å; A204-Y208 PolarHBondContact O-N 2.75Å; T205-Y208 PolarHBondContact O-N 2.69Å; Y208-P210 VanDerWaalsContact C-CD 3.48Å
209	Y	80	Confident	72.9	Confident	46 Å²	46	56 Å²	56	18%	0.18	29%	0.29	C	S	.	.			trans	-128.2	66.9	176.9	-56.4	-70.5	0	0	0	110.4	L167 Q168 T205 D211 L212	L167-Y209 HydrophobicContact CD2-CD2 3.98Å; L167-Y209 HydrophobicContact CD2-CE2 3.57Å; L167-Y209 HydrophobicContact CG-CE2 4.29Å; Q168-Y209 WeakPolarHBondContact CG-OH 3.49Å; Q168-Y209 PolarHBondContact NE2-OH 3.15Å; T205-Y209 HydrophobicContact CG2-CD2 4.31Å; T205-Y209 WeakPolarHBondContact O-CA 3.45Å; T205-Y209 WeakPolarHBondContact O-CB 3.27Å; T205-Y209 PolarHBondContact O-N 2.93Å; Y209-D211 PolarHBondContact O-N 3.33Å; Y209-L212 HydrophobicContact CD2-CD1 4.21Å; Y209-L212 HydrophobicContact CG-CD1 4.02Å; Y209-L212 WeakPolarHBondContact O-CB 3.37Å; Y209-L212 PolarHBondContact O-N 2.95Å; Y209-L212 VanDerWaalsContact O-N 3.14Å
210	P	74.7	Confident	72	Confident	75 Å²	75	55.2 Å²	55.2	49%	0.487	29%	0.285	S	S	.	.	G	3₁₀ helix	trans	-61.8	-27.9	-179.3	26.9	-35	0	0	0	112.3	Y208 L212 C213	Y208-P210 VanDerWaalsContact C-CD 3.48Å; P210-L212 VanDerWaalsContact C-N 3.26Å; P210-L212 PolarHBondContact O-N 3.15Å; P210-C213 WeakPolarHBondContact O-CB 3.24Å; P210-C213 PolarHBondContact O-N 3.32Å
211	D	70.2	Confident	71.6	Confident	103 Å²	103	56.2 Å²	56.2	55%	0.551	29%	0.288	S	S	*	.	G	3₁₀ helix	trans	-73.1	-12.9	179.5	-59.5	-28.1	0	0	0	113.6	Y209 C213 V214 N215	Y209-D211 PolarHBondContact O-N 3.33Å; D211-C213 PolarHBondContact O-N 3.47Å; D211-V214 WeakPolarHBondContact O-CA 3.46Å; D211-V214 PolarHBondContact O-N 3.05Å; D211-N215 PolarHBondContact O-N 3.49Å
212	L	65.9	Low	71.3	Confident	18 Å²	18	56.5 Å²	56.5	9%	0.094	29%	0.289	C	S	.	.	G	3₁₀ helix	trans	-60.9	-22.2	169.1	-75.7	170.2	0	0	0	111.5	T205 Y209 P210 V214 Q218 V220	T205-L212 HydrophobicContact CG2-CD1 3.51Å; Y209-L212 HydrophobicContact CD2-CD1 4.21Å; Y209-L212 HydrophobicContact CG-CD1 4.02Å; Y209-L212 WeakPolarHBondContact O-CB 3.37Å; Y209-L212 PolarHBondContact O-N 2.95Å; Y209-L212 VanDerWaalsContact O-N 3.14Å; P210-L212 VanDerWaalsContact C-N 3.26Å; P210-L212 PolarHBondContact O-N 3.15Å; L212-V214 PolarHBondContact O-N 2.86Å; L212-Q218 HydrophobicContact CD2-CB 3.86Å; L212-V220 HydrophobicContact CD2-CG2 4.24Å
213	C	53.9	Low	70.8	Confident	56 Å²	56	59.5 Å²	59.5	38%	0.378	30%	0.303	S	S	.	.	G	3₁₀ helix	trans	-71.4	-13.3	172.4	-61.8	0	0	0	0	112.9	P210 D211 P290	P210-C213 WeakPolarHBondContact O-CB 3.24Å; P210-C213 PolarHBondContact O-N 3.32Å; D211-C213 PolarHBondContact O-N 3.47Å; C213-P290 VanDerWaalsContact C-CG 3.47Å; C213-P290 VanDerWaalsContact CA-CG 3.46Å; C213-P290 HydrophobicContact CB-CG 4.44Å; C213-P290 WeakPolarHBondContact O-CG 3.41Å
214	V	50.9	Low	70.5	Confident	111 Å²	111	64.2 Å²	64.2	67%	0.673	32%	0.322	S	S	*	.	T	Hydrogen-bonded Turn	trans	-119.1	-39.5	-171.8	-172.4	0	0	0	0	112.1	D211 L212	D211-V214 WeakPolarHBondContact O-CA 3.46Å; D211-V214 PolarHBondContact O-N 3.05Å; L212-V214 PolarHBondContact O-N 2.86Å
215	N	51.1	Low	70.3	Confident	88 Å²	88	66.7 Å²	66.7	47%	0.471	34%	0.335	S	S	.	.			trans	-113.9	103.1	-172.1	-71.5	-20.9	0	0	0	112.4	D211 E217	D211-N215 PolarHBondContact O-N 3.49Å; N215-E217 PolarHBondContact O-N 3.41Å
216	Y	49.3	Very low	70.1	Confident	118 Å²	118	71.5 Å²	71.5	46%	0.463	36%	0.36	S	S	.	.	T	Hydrogen-bonded Turn	trans	-63.9	-14	178.5	-128.8	-82.9	0	0	0	114.6	Q218 S291 V294	Y216-Q218 VanDerWaalsContact C-N 3.32Å; Y216-Q218 PolarHBondContact O-N 3.4Å; Y216-S291 VanDerWaalsContact CZ-CA 3.5Å; Y216-S291 WeakPolarHBondContact OH-CA 3.47Å; Y216-S291 WeakPolarHBondContact OH-CB 3.46Å; Y216-V294 HydrophobicContact CE2-CG2 4.23Å
217	E	47.9	Very low	70.2	Confident	192 Å²	192	70.9 Å²	70.9	90%	0.897	36%	0.358	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.5	-16.2	-171.8	-66.8	-170.8	160.4	0	0	114.3	N215	N215-E217 PolarHBondContact O-N 3.41Å
218	Q	51.6	Low	70.5	Confident	103 Å²	103	69.7 Å²	69.7	48%	0.481	35%	0.351	S	S	.	.	S	Bend	trans	-82.3	131	177.2	-66	-172.7	0.2	0	0	109.5	L212 Y216 V220	L212-Q218 HydrophobicContact CD2-CB 3.86Å; Y216-Q218 VanDerWaalsContact C-N 3.32Å; Y216-Q218 PolarHBondContact O-N 3.4Å; Q218-V220 VanDerWaalsContact C-N 3.28Å; Q218-V220 WeakPolarHBondContact O-CG2 2.97Å; Q218-V220 PolarHBondContact O-N 3.38Å
219	N	53.6	Low	70.7	Confident	129 Å²	129	70 Å²	70	69%	0.69	36%	0.355	S	S	*	.			trans	-44.5	84.2	174.3	-79.7	-48.6	0	0	0	113	W221 K224	N219-W221 PolarHBondContact O-N 3.49Å; N219-K224 WeakPolarHBondContact OD1-CE 3.29Å; N219-K224 PolarHBondContact OD1-NZ 3.19Å
220	V	72.4	Confident	71.2	Confident	10 Å²	10	71 Å²	71	6%	0.061	36%	0.362	C	S	.	.			trans	-73.8	105.1	-177.6	-167.7	0	0	0	0	107.1	L212 Q218 M222 E223 K224 L289	L212-V220 HydrophobicContact CD2-CG2 4.24Å; Q218-V220 VanDerWaalsContact C-N 3.28Å; Q218-V220 WeakPolarHBondContact O-CG2 2.97Å; Q218-V220 PolarHBondContact O-N 3.38Å; V220-M222 HydrophobicContact CG1-CB 3.97Å; V220-M222 HydrophobicContact CG1-CE 3.31Å; V220-M222 HydrophobicContact CG1-CG 4.29Å; V220-M222 HydrophobicContact CG1-SD 4.44Å; V220-M222 PolarHBondContact O-N 3.41Å; V220-E223 HydrophobicContact CB-CB 4.38Å; V220-E223 HydrophobicContact CB-CG 4.14Å; V220-E223 HydrophobicContact CG1-CG 4.39Å; V220-E223 PolarHBondContact O-N 3.36Å; V220-K224 PolarHBondContact O-N 3.07Å; V220-L289 HydrophobicContact CG1-CD1 4.43Å
221	W	82.4	Confident	72	Confident	25 Å²	25	67.6 Å²	67.6	10%	0.095	34%	0.339	C	S	.	.	H	α-helix	trans	-54.6	-30.6	-179.1	66.1	-95.7	0	0	0	112.2	I171 A175 L201 L202 T205 N219 E223 K224 L225 L227	I171-W221 HydrophobicContact CG2-CB 3.65Å; I171-W221 VanDerWaalsContact CG2-CD1 3.46Å; I171-W221 HydrophobicContact CG2-CD2 4.02Å; I171-W221 HydrophobicContact CG2-CG 3.42Å; I171-W221 VanDerWaalsContact CG2-CG 3.42Å; A175-W221 HydrophobicContact CB-CD2 4.33Å; A175-W221 HydrophobicContact CB-CE3 3.7Å; A175-W221 HydrophobicContact CB-CZ3 3.85Å; L201-W221 HydrophobicContact CD2-CH2 3.95Å; L201-W221 HydrophobicContact CD2-CZ2 4.05Å; L201-W221 HydrophobicContact CG-CH2 4.28Å; L201-W221 HydrophobicContact CG-CZ2 4.02Å; L202-W221 HydrophobicContact CD2-CH2 3.83Å; L202-W221 HydrophobicContact CD2-CZ2 3.81Å; L202-W221 HydrophobicContact CG-CH2 4.37Å; T205-W221 PolarHBondContact OG1-NE1 3.25Å; N219-W221 PolarHBondContact O-N 3.49Å; W221-E223 VanDerWaalsContact C-N 3.31Å; W221-E223 PolarHBondContact O-N 3.11Å; W221-K224 PolarHBondContact O-N 3.48Å; W221-L225 HydrophobicContact CE3-CD1 3.85Å; W221-L225 HydrophobicContact CZ3-CD1 4.27Å; W221-L225 WeakPolarHBondContact O-CB 3.46Å; W221-L225 VanDerWaalsContact O-CG 3.31Å; W221-L225 WeakPolarHBondContact O-CG 3.32Å; W221-L225 PolarHBondContact O-N 2.71Å; W221-L227 HydrophobicContact CH2-CD2 4.32Å; W221-L227 HydrophobicContact CZ3-CD2 4.33Å
222	M	85.7	Confident	72.9	Confident	5 Å²	5	62.8 Å²	62.8	3%	0.025	31%	0.313	C	S	.	.	H	α-helix	trans	-61.6	-37.8	177.6	-57.6	170.9	-89.8	0	0	112.2	L202 T205 F206 V220 L226 L227 L289	L202-M222 HydrophobicContact CD2-CG 3.68Å; L202-M222 HydrophobicContact CD2-SD 3.08Å; L202-M222 WeakPolarHBondContact CD2-SD 3.42Å; T205-M222 HydrophobicContact CG2-CE 4.08Å; F206-M222 HydrophobicContact CE1-CE 4.21Å; F206-M222 HydrophobicContact CZ-CE 4.31Å; F206-M222 HydrophobicContact CZ-SD 4.1Å; V220-M222 HydrophobicContact CG1-CB 3.97Å; V220-M222 HydrophobicContact CG1-CE 3.31Å; V220-M222 HydrophobicContact CG1-CG 4.29Å; V220-M222 HydrophobicContact CG1-SD 4.44Å; V220-M222 PolarHBondContact O-N 3.41Å; M222-L226 PolarHBondContact O-N 2.96Å; M222-L227 HydrophobicContact CB-CB 4.36Å; M222-L227 HydrophobicContact CB-CD2 4.22Å; M222-L227 HydrophobicContact CG-CD2 4.15Å; M222-L227 VanDerWaalsContact O-CB 3.29Å; M222-L227 WeakPolarHBondContact O-CB 3.48Å; M222-L227 PolarHBondContact O-N 3.22Å; M222-L289 HydrophobicContact CB-CD1 4.16Å; M222-L289 HydrophobicContact CE-CD1 3.56Å; M222-L289 HydrophobicContact CG-CD1 4.43Å; M222-L289 HydrophobicContact SD-CD1 3.41Å; M222-L289 WeakPolarHBondContact SD-CD1 3.47Å
223	E	80	Confident	74.1	Confident	63 Å²	63	66.4 Å²	66.4	29%	0.294	33%	0.33	S	S	.	.	H	α-helix	trans	-78.2	-43.4	178.1	-69.6	169.8	-160.3	0	0	111.4	V220 W221 L225 L226 S291	V220-E223 HydrophobicContact CB-CB 4.38Å; V220-E223 HydrophobicContact CB-CG 4.14Å; V220-E223 HydrophobicContact CG1-CG 4.39Å; V220-E223 PolarHBondContact O-N 3.36Å; W221-E223 VanDerWaalsContact C-N 3.31Å; W221-E223 PolarHBondContact O-N 3.11Å; E223-L225 PolarHBondContact O-N 2.91Å; E223-L226 PolarHBondContact O-N 3.14Å; E223-S291 WeakPolarHBondContact OE1-CB 3.36Å; E223-S291 PolarHBondContact OE1-OG 3.01Å
224	K	82.4	Confident	75.9	Confident	137 Å²	137	64 Å²	64	60%	0.596	31%	0.313	S	S	*	.	H	α-helix	trans	-58.9	-33.8	175.8	-69.1	-170.6	177	-172.1	0	112.6	N219 V220 W221 L226	N219-K224 WeakPolarHBondContact OD1-CE 3.29Å; N219-K224 PolarHBondContact OD1-NZ 3.19Å; V220-K224 PolarHBondContact O-N 3.07Å; W221-K224 PolarHBondContact O-N 3.48Å; K224-L226 VanDerWaalsContact C-N 3.34Å
225	L	84.8	Confident	77.8	Confident	51 Å²	51	58.7 Å²	58.7	27%	0.267	28%	0.281	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.5	5.1	176	-65.1	-175.6	0	0	0	113.5	A175 V179 W221 E223 L227 H230	A175-L225 VanDerWaalsContact C-CD1 3.48Å; A175-L225 HydrophobicContact CB-CD1 3.65Å; V179-L225 HydrophobicContact CG2-CB 4.34Å; V179-L225 HydrophobicContact CG2-CD1 4.07Å; W221-L225 HydrophobicContact CE3-CD1 3.85Å; W221-L225 HydrophobicContact CZ3-CD1 4.27Å; W221-L225 WeakPolarHBondContact O-CB 3.46Å; W221-L225 VanDerWaalsContact O-CG 3.31Å; W221-L225 WeakPolarHBondContact O-CG 3.32Å; W221-L225 PolarHBondContact O-N 2.71Å; E223-L225 PolarHBondContact O-N 2.91Å; L225-L227 PolarHBondContact O-N 3.42Å; L225-L227 VanDerWaalsContact O-N 3.14Å; L225-H230 PolarHBondContact O-CD2 2.77Å; L225-H230 VanDerWaalsContact O-CD2 3.25Å
226	L	83.4	Confident	79.7	Confident	101 Å²	101	57.3 Å²	57.3	53%	0.529	27%	0.272	S	S	.	.	T	Hydrogen-bonded Turn	trans	50	39.4	-179.1	-59.6	173.9	0	0	0	112.6	M222 E223 K224 F228 S229 H230	M222-L226 PolarHBondContact O-N 2.96Å; E223-L226 PolarHBondContact O-N 3.14Å; K224-L226 VanDerWaalsContact C-N 3.34Å; L226-F228 VanDerWaalsContact C-N 3.29Å; L226-F228 PolarHBondContact O-N 3.17Å; L226-S229 WeakPolarHBondContact O-CB 3.47Å; L226-S229 PolarHBondContact O-N 3.41Å; L226-S229 VanDerWaalsContact O-N 3.08Å; L226-H230 PolarHBondContact O-CD2 3.07Å; L226-H230 PolarHBondContact O-N 2.92Å
227	L	88.3	Confident	81.6	Confident	4 Å²	4	59.7 Å²	59.7	2%	0.021	28%	0.28	C	S	.	.	H	α-helix	trans	-56.3	-43.6	-168.9	179.2	65.4	0	0	0	111.9	V179 L198 L202 W221 M222 L225 H230 V231 I285	V179-L227 HydrophobicContact CG2-CD1 3.77Å; L198-L227 HydrophobicContact CD1-CD1 4.17Å; L202-L227 HydrophobicContact CD1-CD2 4.08Å; L202-L227 HydrophobicContact CD2-CD2 3.81Å; L202-L227 HydrophobicContact CG-CD2 4.27Å; W221-L227 HydrophobicContact CH2-CD2 4.32Å; W221-L227 HydrophobicContact CZ3-CD2 4.33Å; M222-L227 HydrophobicContact CB-CB 4.36Å; M222-L227 HydrophobicContact CB-CD2 4.22Å; M222-L227 HydrophobicContact CG-CD2 4.15Å; M222-L227 VanDerWaalsContact O-CB 3.29Å; M222-L227 WeakPolarHBondContact O-CB 3.48Å; M222-L227 PolarHBondContact O-N 3.22Å; L225-L227 PolarHBondContact O-N 3.42Å; L225-L227 VanDerWaalsContact O-N 3.14Å; L227-H230 PolarHBondContact O-N 3.39Å; L227-V231 HydrophobicContact CD1-CG2 4.34Å; L227-V231 VanDerWaalsContact O-CG2 3.3Å; L227-V231 WeakPolarHBondContact O-CG2 3.33Å; L227-V231 PolarHBondContact O-N 3.39Å; L227-I285 HydrophobicContact CD2-CD1 4.01Å; L227-I285 HydrophobicContact CD2-CG1 4.28Å; L227-I285 HydrophobicContact CG-CD1 3.86Å
228	F	88.7	Confident	83.5	Confident	15 Å²	15	52 Å²	52	7%	0.066	25%	0.245	C	C	.	.	H	α-helix	trans	-59.5	-51.4	176.5	175.2	-109.4	0	0	0	111.8	L226 H230 V231 V232 L282 I285 L286 V292 L295 F315	L226-F228 VanDerWaalsContact C-N 3.29Å; L226-F228 PolarHBondContact O-N 3.17Å; F228-H230 VanDerWaalsContact C-N 3.3Å; F228-H230 PolarHBondContact O-N 2.91Å; F228-V231 PolarHBondContact O-N 3.17Å; F228-V232 HydrophobicContact CD1-CG2 4.46Å; F228-V232 HydrophobicContact CD2-CG2 4.06Å; F228-V232 HydrophobicContact CE1-CG2 4.08Å; F228-V232 HydrophobicContact CE2-CG2 3.64Å; F228-V232 HydrophobicContact CG-CG2 4.47Å; F228-V232 HydrophobicContact CZ-CG2 3.65Å; F228-V232 WeakPolarHBondContact O-CG2 3.31Å; F228-V232 PolarHBondContact O-N 2.86Å; F228-L282 HydrophobicContact CD2-CD1 4.25Å; F228-L282 HydrophobicContact CE2-CD1 3.97Å; F228-I285 HydrophobicContact CB-CG2 4.27Å; F228-I285 HydrophobicContact CD2-CG2 3.99Å; F228-L286 HydrophobicContact CE2-CD2 4.22Å; F228-V292 HydrophobicContact CB-CG2 3.68Å; F228-V292 HydrophobicContact CD1-CG2 4.02Å; F228-V292 HydrophobicContact CD2-CG1 4.1Å; F228-V292 HydrophobicContact CD2-CG2 3.73Å; F228-V292 HydrophobicContact CE2-CG1 3.97Å; F228-V292 HydrophobicContact CE2-CG2 4.35Å; F228-V292 HydrophobicContact CG-CG2 3.52Å; F228-V292 HydrophobicContact CZ-CG1 4.34Å; F228-L295 HydrophobicContact CD1-CD2 4.17Å; F228-L295 HydrophobicContact CE1-CD2 3.9Å; F228-F315 HydrophobicContact CE2-CD2 4.13Å; F228-F315 HydrophobicContact CE2-CE2 4.38Å; F228-F315 HydrophobicContact CZ-CB 4.34Å; F228-F315 AromaticContact CZ-CD2 3.87Å; F228-F315 HydrophobicContact CZ-CD2 3.87Å; F228-F315 HydrophobicContact CZ-CE2 4.4Å; F228-F315 HydrophobicContact CZ-CG 4.07Å
229	S	87.8	Confident	85.4	Confident	21 Å²	21	47.4 Å²	47.4	15%	0.147	22%	0.224	C	C	.	.	H	α-helix	trans	-58.3	-42.1	179	-52.2	0	0	0	0	112	L226 H233 E311	L226-S229 WeakPolarHBondContact O-CB 3.47Å; L226-S229 PolarHBondContact O-N 3.41Å; L226-S229 VanDerWaalsContact O-N 3.08Å; S229-H233 WeakPolarHBondContact O-CB 3.37Å; S229-H233 PolarHBondContact O-N 3.11Å; S229-E311 WeakPolarHBondContact CB-OE1 3.39Å; S229-E311 PolarHBondContact OG-OE1 3.28Å; S229-E311 PolarHBondContact OG-OE2 3.43Å
230	H	89.6	Confident	87.1	Confident	67 Å²	67	42.6 Å²	42.6	31%	0.31	20%	0.199	S	C	.	.	H	α-helix	trans	-62.1	-47.6	175.6	-84.3	-75.6	0	0	0	111.9	V179 L225 L226 L227 F228 H233 V234	V179-H230 HydrophobicContact CG1-CB 4.15Å; L225-H230 PolarHBondContact O-CD2 2.77Å; L225-H230 VanDerWaalsContact O-CD2 3.25Å; L226-H230 PolarHBondContact O-CD2 3.07Å; L226-H230 PolarHBondContact O-N 2.92Å; L227-H230 PolarHBondContact O-N 3.39Å; F228-H230 VanDerWaalsContact C-N 3.3Å; F228-H230 PolarHBondContact O-N 2.91Å; H230-H233 PolarHBondContact O-N 3.43Å; H230-V234 WeakPolarHBondContact O-CG2 3.45Å; H230-V234 PolarHBondContact O-N 3.05Å
231	V	91.4	Very high	88	Confident	2 Å²	2	50.1 Å²	50.1	1%	0.012	23%	0.231	C	C	.	.	H	α-helix	trans	-63.7	-44.7	-179.6	173.2	0	0	0	0	111.3	L227 F228 H233 V234 L235 L281 L282 I285	L227-V231 HydrophobicContact CD1-CG2 4.34Å; L227-V231 VanDerWaalsContact O-CG2 3.3Å; L227-V231 WeakPolarHBondContact O-CG2 3.33Å; L227-V231 PolarHBondContact O-N 3.39Å; F228-V231 PolarHBondContact O-N 3.17Å; V231-H233 VanDerWaalsContact C-N 3.35Å; V231-H233 PolarHBondContact O-N 3.27Å; V231-V234 PolarHBondContact O-N 3.24Å; V231-L235 HydrophobicContact CG1-CD1 4.05Å; V231-L235 WeakPolarHBondContact O-CG 3.41Å; V231-L235 PolarHBondContact O-N 3.3Å; V231-L281 HydrophobicContact CG2-CD2 3.57Å; V231-L281 HydrophobicContact CG2-CG 4Å; V231-L282 HydrophobicContact CG1-CB 3.8Å; V231-L282 HydrophobicContact CG1-CD1 4.21Å; V231-I285 HydrophobicContact CB-CD1 4.35Å; V231-I285 HydrophobicContact CG2-CD1 3.86Å
232	V	90.7	Very high	88.3	Confident	2 Å²	2	50.4 Å²	50.4	1%	0.012	24%	0.236	C	C	.	.	H	α-helix	trans	-61.6	-44.2	176	171.5	0	0	0	0	110.9	F228 V234 L235 H236 L282 K314 F315 I318	F228-V232 HydrophobicContact CD1-CG2 4.46Å; F228-V232 HydrophobicContact CD2-CG2 4.06Å; F228-V232 HydrophobicContact CE1-CG2 4.08Å; F228-V232 HydrophobicContact CE2-CG2 3.64Å; F228-V232 HydrophobicContact CG-CG2 4.47Å; F228-V232 HydrophobicContact CZ-CG2 3.65Å; F228-V232 WeakPolarHBondContact O-CG2 3.31Å; F228-V232 PolarHBondContact O-N 2.86Å; V232-V234 PolarHBondContact O-N 2.97Å; V232-L235 PolarHBondContact O-N 2.81Å; V232-H236 VanDerWaalsContact O-CB 3.29Å; V232-H236 WeakPolarHBondContact O-CB 3.46Å; V232-H236 PolarHBondContact O-N 2.91Å; V232-L282 HydrophobicContact CG2-CD1 4.34Å; V232-K314 HydrophobicContact CG1-CB 3.89Å; V232-F315 HydrophobicContact CG1-CB 4.24Å; V232-F315 HydrophobicContact CG2-CB 4.4Å; V232-F315 HydrophobicContact CG2-CD2 4.3Å; V232-I318 HydrophobicContact CG1-CD1 4.16Å
233	H	90.3	Very high	88.5	Confident	94 Å²	94	50.2 Å²	50.2	44%	0.435	23%	0.234	S	C	.	.	H	α-helix	trans	-61.5	-44.1	178.5	-178.2	69.7	0	0	0	112.3	S229 H230 V231 H236 R237	S229-H233 WeakPolarHBondContact O-CB 3.37Å; S229-H233 PolarHBondContact O-N 3.11Å; H230-H233 PolarHBondContact O-N 3.43Å; V231-H233 VanDerWaalsContact C-N 3.35Å; V231-H233 PolarHBondContact O-N 3.27Å; H233-H236 PolarHBondContact O-N 3.41Å; H233-R237 WeakPolarHBondContact O-CB 3.3Å; H233-R237 PolarHBondContact O-N 2.79Å
234	V	90.6	Very high	89	Confident	5 Å²	5	48 Å²	48	3%	0.03	23%	0.225	C	C	.	.	H	α-helix	trans	-64.3	-47.6	178.7	174.6	0	0	0	0	110.6	H230 V231 V232 H236 R237 L238 H278	H230-V234 WeakPolarHBondContact O-CG2 3.45Å; H230-V234 PolarHBondContact O-N 3.05Å; V231-V234 PolarHBondContact O-N 3.24Å; V232-V234 PolarHBondContact O-N 2.97Å; V234-H236 VanDerWaalsContact C-N 3.34Å; V234-H236 PolarHBondContact O-N 3.37Å; V234-R237 PolarHBondContact O-N 3.15Å; V234-L238 HydrophobicContact CG1-CD1 3.66Å; V234-L238 HydrophobicContact CG1-CG 4.06Å; V234-L238 WeakPolarHBondContact O-CB 3.26Å; V234-L238 VanDerWaalsContact O-CG 3.27Å; V234-L238 WeakPolarHBondContact O-CG 3.32Å; V234-L238 PolarHBondContact O-N 3.21Å; V234-H278 WeakPolarHBondContact CG1-NE2 3.17Å
235	L	92	Very high	89.2	Confident	0 Å²	0	46.1 Å²	46.1	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-59.4	-44.5	176.7	-74.2	171.5	0	0	0	112.2	V231 V232 R237 L238 L239 L275 H278 L279 L282 I318	V231-L235 HydrophobicContact CG1-CD1 4.05Å; V231-L235 WeakPolarHBondContact O-CG 3.41Å; V231-L235 PolarHBondContact O-N 3.3Å; V232-L235 PolarHBondContact O-N 2.81Å; L235-R237 PolarHBondContact O-N 3.11Å; L235-L238 PolarHBondContact O-N 2.84Å; L235-L239 WeakPolarHBondContact O-CB 3.47Å; L235-L239 WeakPolarHBondContact O-CG 3.41Å; L235-L239 PolarHBondContact O-N 3.16Å; L235-L275 HydrophobicContact CD2-CD1 3.6Å; L235-H278 HydrophobicContact CD2-CB 3.55Å; L235-H278 HydrophobicContact CG-CB 3.98Å; L235-L279 HydrophobicContact CD1-CD2 4.19Å; L235-L279 HydrophobicContact CD2-CD2 3.94Å; L235-L279 HydrophobicContact CD2-CG 4.08Å; L235-L282 HydrophobicContact CD1-CB 4.08Å; L235-L282 HydrophobicContact CD1-CD2 3.54Å; L235-L282 HydrophobicContact CD1-CG 4.31Å; L235-I318 HydrophobicContact CB-CD1 3.77Å
236	H	90.6	Very high	89	Confident	59 Å²	59	49.6 Å²	49.6	27%	0.273	23%	0.234	S	C	.	.	H	α-helix	trans	-63.4	-29.4	176.2	-174.6	-66.1	0	0	0	112.5	V232 H233 V234 L244 K314 I318	V232-H236 VanDerWaalsContact O-CB 3.29Å; V232-H236 WeakPolarHBondContact O-CB 3.46Å; V232-H236 PolarHBondContact O-N 2.91Å; H233-H236 PolarHBondContact O-N 3.41Å; V234-H236 VanDerWaalsContact C-N 3.34Å; V234-H236 PolarHBondContact O-N 3.37Å; H236-L244 HydrophobicContact CB-CD1 4.46Å; H236-K314 VanDerWaalsContact CD2-CG 3.47Å; H236-K314 WeakPolarHBondContact CD2-CG 3.4Å; H236-I318 HydrophobicContact CB-CD1 4.37Å
237	R	88.9	Confident	88.6	Confident	169 Å²	169	46 Å²	46	64%	0.638	22%	0.217	S	C	*	.	H	α-helix	trans	-81.3	-36.6	176.5	-176.5	179	175.1	-178.4	-1.6	112.4	H233 V234 L235	H233-R237 WeakPolarHBondContact O-CB 3.3Å; H233-R237 PolarHBondContact O-N 2.79Å; V234-R237 PolarHBondContact O-N 3.15Å; L235-R237 PolarHBondContact O-N 3.11Å
238	L	89.1	Confident	88	Confident	30 Å²	30	51.5 Å²	51.5	16%	0.157	26%	0.256	C	S	.	.	H	α-helix	trans	-67.8	-38	178.3	-74	172.4	0	0	0	111.6	V234 L235 L270 I274	V234-L238 HydrophobicContact CG1-CD1 3.66Å; V234-L238 HydrophobicContact CG1-CG 4.06Å; V234-L238 WeakPolarHBondContact O-CB 3.26Å; V234-L238 VanDerWaalsContact O-CG 3.27Å; V234-L238 WeakPolarHBondContact O-CG 3.32Å; V234-L238 PolarHBondContact O-N 3.21Å; L235-L238 PolarHBondContact O-N 2.84Å; L238-L270 WeakPolarHBondContact O-CD2 3.33Å; L238-I274 HydrophobicContact CD1-CG2 3.63Å; L238-I274 HydrophobicContact CD2-CG2 4.14Å
239	L	91.1	Very high	87.3	Confident	7 Å²	7	54.6 Å²	54.6	4%	0.037	27%	0.273	C	S	.	.	S	Bend	trans	-81.2	128.2	179.4	-68.5	172.5	0	0	0	111.2	L235 F243 L244 L275 L326	L235-L239 WeakPolarHBondContact O-CB 3.47Å; L235-L239 WeakPolarHBondContact O-CG 3.41Å; L235-L239 PolarHBondContact O-N 3.16Å; L239-F243 HydrophobicContact CB-CB 4.31Å; L239-F243 HydrophobicContact CD2-CB 4.48Å; L239-L244 HydrophobicContact CB-CD1 4.39Å; L239-L244 HydrophobicContact CB-CD2 4.22Å; L239-L244 HydrophobicContact CB-CG 4.26Å; L239-L244 HydrophobicContact CD1-CD2 3.89Å; L239-L275 HydrophobicContact CD2-CD1 4.19Å; L239-L275 HydrophobicContact CD2-CD2 4.03Å; L239-L275 HydrophobicContact CG-CD1 4.37Å; L239-L326 HydrophobicContact CD2-CD1 4.24Å; L239-L326 HydrophobicContact CD2-CD2 4.15Å; L239-L326 HydrophobicContact CD2-CG 4.36Å
240	P	89.8	Confident	86.9	Confident	28 Å²	28	55.1 Å²	55.1	18%	0.182	27%	0.273	C	S	.	.			trans	-57	147.6	170.7	-20.6	27.1	0	0	0	110.7	V242 F243 H262 L270	P240-V242 PolarHBondContact O-N 2.74Å; P240-F243 HydrophobicContact CB-CD2 3.91Å; P240-F243 HydrophobicContact CB-CE2 4.31Å; P240-F243 HydrophobicContact CG-CD2 3.83Å; P240-F243 HydrophobicContact CG-CE2 3.9Å; P240-F243 WeakPolarHBondContact O-CB 3.26Å; P240-F243 PolarHBondContact O-N 3.36Å; P240-H262 HydrophobicContact CG-CB 4.11Å; P240-L270 HydrophobicContact CG-CD2 4.41Å
241	K	89.5	Confident	86.1	Confident	168 Å²	168	52 Å²	52	73%	0.73	26%	0.258	S	S	*	.	G	3₁₀ helix	trans	-53	-32	-177.5	-67.8	-175.4	179.1	-179.4	0	113.6	F243 L244 M245	K241-F243 PolarHBondContact O-N 2.96Å; K241-L244 PolarHBondContact O-N 2.82Å; K241-M245 HydrophobicContact CB-CE 4.04Å; K241-M245 VanDerWaalsContact O-CE 3.23Å; K241-M245 WeakPolarHBondContact O-CE 3.36Å
242	V	88.5	Confident	85.7	Confident	31 Å²	31	54.1 Å²	54.1	19%	0.188	27%	0.272	C	S	.	.	G	3₁₀ helix	trans	-60.5	-29.4	177.8	-173	0	0	0	0	112.1	P240 L244 L255 L259 N325	P240-V242 PolarHBondContact O-N 2.74Å; V242-L244 VanDerWaalsContact C-N 3.3Å; V242-L244 PolarHBondContact O-N 2.78Å; V242-L255 HydrophobicContact CG1-CD1 4.36Å; V242-L259 HydrophobicContact CB-CD2 4.38Å; V242-L259 HydrophobicContact CG1-CD2 3.74Å; V242-N325 PolarHBondContact O-ND2 3.41Å
243	F	91.2	Very high	85.4	Confident	0 Å²	0	57 Å²	57	0%	0	28%	0.283	C	S	.	.	G	3₁₀ helix	trans	-76	-17.7	177.1	-74.2	-103.6	0	0	0	113.2	L239 P240 K241 L259 H262 L270 Y321 G322 N325 L326 A329	L239-F243 HydrophobicContact CB-CB 4.31Å; L239-F243 HydrophobicContact CD2-CB 4.48Å; P240-F243 HydrophobicContact CB-CD2 3.91Å; P240-F243 HydrophobicContact CB-CE2 4.31Å; P240-F243 HydrophobicContact CG-CD2 3.83Å; P240-F243 HydrophobicContact CG-CE2 3.9Å; P240-F243 WeakPolarHBondContact O-CB 3.26Å; P240-F243 PolarHBondContact O-N 3.36Å; K241-F243 PolarHBondContact O-N 2.96Å; F243-L259 HydrophobicContact CD1-CD2 4.31Å; F243-L259 HydrophobicContact CD2-CD2 3.91Å; F243-L259 HydrophobicContact CE1-CD2 4.12Å; F243-L259 HydrophobicContact CE2-CD2 3.71Å; F243-L259 HydrophobicContact CG-CD2 4.22Å; F243-L259 HydrophobicContact CZ-CB 4.3Å; F243-L259 HydrophobicContact CZ-CD2 3.82Å; F243-H262 HydrophobicContact CE2-CB 4.03Å; F243-H262 AromaticContact CE2-CD2 3.87Å; F243-H262 HydrophobicContact CZ-CB 4.35Å; F243-L270 HydrophobicContact CZ-CD1 4.35Å; F243-Y321 CarbonylContact O-C 3.5Å; F243-G322 WeakPolarHBondContact O-CA 3.36Å; F243-G322 PolarHBondContact O-N 2.89Å; F243-N325 HydrophobicContact CB-CB 4.26Å; F243-N325 HydrophobicContact CD1-CB 3.64Å; F243-N325 HydrophobicContact CE1-CB 4.3Å; F243-N325 HydrophobicContact CG-CB 4.18Å; F243-N325 PolarHBondContact O-ND2 3.2Å; F243-L326 HydrophobicContact CD1-CD2 4.09Å; F243-L326 HydrophobicContact CD1-CG 4.03Å; F243-L326 HydrophobicContact CE1-CD2 3.82Å; F243-L326 HydrophobicContact CE1-CG 4.15Å; F243-A329 HydrophobicContact CE1-CB 3.83Å; F243-A329 HydrophobicContact CZ-CB 3.88Å
244	L	90.8	Very high	85.2	Confident	18 Å²	18	59.3 Å²	59.3	9%	0.094	29%	0.294	C	S	.	.	G	3₁₀ helix	trans	-106.2	10.8	-170.1	-60.7	176	0	0	0	113.1	H236 L239 K241 V242 A317 I318	H236-L244 HydrophobicContact CB-CD1 4.46Å; L239-L244 HydrophobicContact CB-CD1 4.39Å; L239-L244 HydrophobicContact CB-CD2 4.22Å; L239-L244 HydrophobicContact CB-CG 4.26Å; L239-L244 HydrophobicContact CD1-CD2 3.89Å; K241-L244 PolarHBondContact O-N 2.82Å; V242-L244 VanDerWaalsContact C-N 3.3Å; V242-L244 PolarHBondContact O-N 2.78Å; L244-A317 HydrophobicContact CB-CB 4.17Å; L244-A317 HydrophobicContact CD2-CB 4.42Å; L244-A317 WeakPolarHBondContact O-CB 3.07Å; L244-I318 HydrophobicContact CD2-CG1 3.8Å
245	M	86.5	Confident	85	Confident	97 Å²	97	59.5 Å²	59.5	48%	0.478	30%	0.295	S	S	.	.	S	Bend	trans	-131.4	152.9	179.9	64.2	177.8	100.4	0	0	111.2	K241 S247	K241-M245 HydrophobicContact CB-CE 4.04Å; K241-M245 VanDerWaalsContact O-CE 3.23Å; K241-M245 WeakPolarHBondContact O-CE 3.36Å; M245-S247 PolarHBondContact O-N 2.88Å
246	E	79.7	Confident	84.8	Confident	124 Å²	124	59.5 Å²	59.5	58%	0.579	30%	0.295	S	S	*	.			trans	-69.9	125.7	167.2	-167.1	172.3	-165.9	0	0	109.2	Y321	E246-Y321 HydrophobicContact CB-CD1 4.16Å; E246-Y321 HydrophobicContact CB-CE1 3.56Å; E246-Y321 HydrophobicContact CG-CE1 4Å
247	S	76.2	Confident	84.5	Confident	24 Å²	24	63.1 Å²	63.1	17%	0.168	31%	0.309	C	S	.	.			trans	-87.6	128.2	175.2	60.1	0	0	0	0	110.1	M245 N249 F250 L255	M245-S247 PolarHBondContact O-N 2.88Å; S247-N249 PolarHBondContact O-N 3.26Å; S247-N249 VanDerWaalsContact O-N 3.14Å; S247-F250 PolarHBondContact O-N 2.97Å; S247-F250 VanDerWaalsContact O-N 3.17Å; S247-F250 VanDerWaalsContact OG-CA 3.24Å; S247-F250 WeakPolarHBondContact OG-CA 3.38Å; S247-F250 PolarHBondContact OG-N 3.38Å; S247-L255 WeakPolarHBondContact OG-CD2 3.42Å
248	S	74.3	Confident	84.5	Confident	120 Å²	120	59.6 Å²	59.6	84%	0.839	30%	0.3	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.9	-27.5	167.5	59.8	0	0	0	0	112.6	F250	S248-F250 VanDerWaalsContact C-N 3.35Å
249	N	74.7	Confident	84.6	Confident	81 Å²	81	58.2 Å²	58.2	43%	0.433	29%	0.293	S	S	.	.	T	Hydrogen-bonded Turn	trans	-100	32.9	-177.7	-59.4	-0.3	0	0	0	111.6	S247 G251 T252	S247-N249 PolarHBondContact O-N 3.26Å; S247-N249 VanDerWaalsContact O-N 3.14Å; N249-G251 PolarHBondContact O-N 3.22Å; N249-T252 HydrophobicContact CB-CG2 3.87Å; N249-T252 WeakPolarHBondContact CB-OG1 3.07Å; N249-T252 WeakPolarHBondContact O-CB 3.47Å; N249-T252 WeakPolarHBondContact O-CG2 2.91Å; N249-T252 PolarHBondContact O-N 3.41Å; N249-T252 PolarHBondContact O-OG1 3.42Å
250	F	78.6	Confident	84.4	Confident	32 Å²	32	58.5 Å²	58.5	14%	0.14	30%	0.296	C	S	.	.	T	Hydrogen-bonded Turn	trans	-52.6	130	-179.1	179.6	-98.8	0	0	0	110.8	S247 S248 T252 M324 L328 L348 F349 N412 C416	S247-F250 PolarHBondContact O-N 2.97Å; S247-F250 VanDerWaalsContact O-N 3.17Å; S247-F250 VanDerWaalsContact OG-CA 3.24Å; S247-F250 WeakPolarHBondContact OG-CA 3.38Å; S247-F250 PolarHBondContact OG-N 3.38Å; S248-F250 VanDerWaalsContact C-N 3.35Å; F250-T252 VanDerWaalsContact C-N 3.29Å; F250-T252 PolarHBondContact O-N 2.94Å; F250-M324 HydrophobicContact CD2-CE 3.92Å; F250-M324 HydrophobicContact CD2-SD 4.3Å; F250-M324 HydrophobicContact CE2-CE 3.57Å; F250-M324 HydrophobicContact CE2-CG 4.02Å; F250-M324 HydrophobicContact CE2-SD 3.42Å; F250-M324 WeakPolarHBondContact CE2-SD 3.31Å; F250-M324 HydrophobicContact CZ-SD 3.92Å; F250-L328 HydrophobicContact CD2-CD1 4.2Å; F250-L328 HydrophobicContact CE2-CD1 3.73Å; F250-L328 HydrophobicContact CZ-CD1 4.49Å; F250-L348 HydrophobicContact CE1-CD2 4.42Å; F250-F349 HydrophobicContact CD1-CE2 4.3Å; F250-F349 HydrophobicContact CD1-CZ 4.17Å; F250-F349 HydrophobicContact CE1-CZ 4.28Å; F250-N412 HydrophobicContact CE1-CB 4Å; F250-N412 HydrophobicContact CE2-CB 4.25Å; F250-N412 HydrophobicContact CZ-CB 3.66Å; F250-C416 WeakPolarHBondContact CZ-SG 3.46Å
251	G	74.4	Confident	84.3	Confident	0 Å²	0	61.9 Å²	61.9	0%	0	31%	0.308	C	S	.	.	T	Hydrogen-bonded Turn	trans	75	6.5	-179	0	0	0	0	0	115.9	N249 L348	N249-G251 PolarHBondContact O-N 3.22Å; G251-L348 VanDerWaalsContact O-CB 3.25Å; G251-L348 WeakPolarHBondContact O-CB 3.34Å; G251-L348 PolarHBondContact O-N 3.48Å
252	T	83.2	Confident	84.1	Confident	47 Å²	47	55.5 Å²	55.5	29%	0.288	28%	0.28	S	S	.	.			trans	-77.4	149.4	171.6	60.7	0	0	0	0	111.9	N249 F250 E254 L255 L256	N249-T252 HydrophobicContact CB-CG2 3.87Å; N249-T252 WeakPolarHBondContact CB-OG1 3.07Å; N249-T252 WeakPolarHBondContact O-CB 3.47Å; N249-T252 WeakPolarHBondContact O-CG2 2.91Å; N249-T252 PolarHBondContact O-N 3.41Å; N249-T252 PolarHBondContact O-OG1 3.42Å; F250-T252 VanDerWaalsContact C-N 3.29Å; F250-T252 PolarHBondContact O-N 2.94Å; T252-E254 PolarHBondContact O-N 2.92Å; T252-L255 PolarHBondContact O-N 3.18Å; T252-L255 WeakPolarHBondContact OG1-CB 3.42Å; T252-L255 PolarHBondContact OG1-N 3.38Å; T252-L256 WeakPolarHBondContact O-CG 3.37Å; T252-L256 PolarHBondContact O-N 2.9Å; T252-L256 VanDerWaalsContact O-N 3.09Å
253	Y	83.5	Confident	83.9	Confident	62 Å²	62	55.2 Å²	55.2	24%	0.243	28%	0.277	C	S	.	.	H	α-helix	trans	-58.5	-33.7	174.8	-177.3	-101.1	0	0	0	113.3	L256 K257 K332 S340 L343 T344	Y253-L256 PolarHBondContact O-N 3.19Å; Y253-K257 WeakPolarHBondContact O-CB 3.39Å; Y253-K257 PolarHBondContact O-N 3.22Å; Y253-K332 HydrophobicContact CE2-CD 4.23Å; Y253-S340 WeakPolarHBondContact CE2-OG 3.43Å; Y253-S340 PolarHBondContact OH-OG 3.11Å; Y253-S340 VanDerWaalsContact OH-OG 3.12Å; Y253-L343 WeakPolarHBondContact CB-O 3.48Å; Y253-L343 HydrophobicContact CD2-CB 3.95Å; Y253-T344 HydrophobicContact CD1-CG2 3.7Å; Y253-T344 HydrophobicContact CD2-CG2 4.11Å; Y253-T344 HydrophobicContact CE1-CG2 3.58Å; Y253-T344 HydrophobicContact CE2-CG2 4.01Å; Y253-T344 HydrophobicContact CG-CG2 3.96Å
254	E	85.3	Confident	83.4	Confident	143 Å²	143	59.1 Å²	59.1	67%	0.668	30%	0.301	S	S	*	.	H	α-helix	trans	-65.2	-46.3	178.1	-173.2	173.3	-163.4	0	0	112	T252 L256 K257 Q258	T252-E254 PolarHBondContact O-N 2.92Å; E254-L256 VanDerWaalsContact C-N 3.33Å; E254-L256 PolarHBondContact O-N 3.25Å; E254-K257 PolarHBondContact O-N 3.42Å; E254-Q258 PolarHBondContact O-N 2.83Å
255	L	87.2	Confident	82.5	Confident	10 Å²	10	60.9 Å²	60.9	5%	0.052	31%	0.311	C	S	.	.	H	α-helix	trans	-59.2	-46.4	173.7	177.2	69.2	0	0	0	111	V242 S247 T252 K257 Q258 L259	V242-L255 HydrophobicContact CG1-CD1 4.36Å; S247-L255 WeakPolarHBondContact OG-CD2 3.42Å; T252-L255 PolarHBondContact O-N 3.18Å; T252-L255 WeakPolarHBondContact OG1-CB 3.42Å; T252-L255 PolarHBondContact OG1-N 3.38Å; L255-K257 VanDerWaalsContact C-N 3.3Å; L255-K257 PolarHBondContact O-N 3.36Å; L255-Q258 PolarHBondContact O-N 3.44Å; L255-L259 HydrophobicContact CD1-CD1 4.17Å; L255-L259 HydrophobicContact CD1-CG 4.15Å; L255-L259 HydrophobicContact CD2-CD1 4.45Å; L255-L259 HydrophobicContact CG-CD1 3.93Å; L255-L259 HydrophobicContact CG-CG 4.29Å; L255-L259 WeakPolarHBondContact O-CB 3.36Å; L255-L259 WeakPolarHBondContact O-CG 3.36Å; L255-L259 PolarHBondContact O-N 3.47Å
256	L	87.2	Confident	81.6	Confident	0 Å²	0	60.4 Å²	60.4	0%	0	32%	0.322	C	S	.	.	H	α-helix	trans	-56.3	-46.8	178.1	-68.3	178.6	0	0	0	111.2	T252 Y253 E254 L259 S260 L328 K332 L343 Y419	T252-L256 WeakPolarHBondContact O-CG 3.37Å; T252-L256 PolarHBondContact O-N 2.9Å; T252-L256 VanDerWaalsContact O-N 3.09Å; Y253-L256 PolarHBondContact O-N 3.19Å; E254-L256 VanDerWaalsContact C-N 3.33Å; E254-L256 PolarHBondContact O-N 3.25Å; L256-L259 PolarHBondContact O-N 3.24Å; L256-S260 WeakPolarHBondContact O-CB 3.43Å; L256-S260 PolarHBondContact O-N 3.23Å; L256-S260 PolarHBondContact O-OG 3.3Å; L256-L328 HydrophobicContact CD2-CB 3.81Å; L256-L328 HydrophobicContact CD2-CD2 3.94Å; L256-L328 HydrophobicContact CD2-CG 4.31Å; L256-K332 HydrophobicContact CB-CB 4.07Å; L256-K332 HydrophobicContact CB-CD 3.64Å; L256-K332 HydrophobicContact CB-CG 4.02Å; L256-K332 WeakPolarHBondContact O-CG 3.49Å; L256-L343 HydrophobicContact CD1-CD2 4.13Å; L256-Y419 HydrophobicContact CD1-CE2 4.46Å; L256-Y419 HydrophobicContact CD2-CE1 4.23Å
257	K	85.9	Confident	81	Confident	134 Å²	134	62.2 Å²	62.2	58%	0.583	34%	0.336	S	S	*	.	H	α-helix	trans	-62.2	-41.9	177.7	-174.6	-178.1	178.9	-176	0	112	Y253 E254 L255 S260 K261	Y253-K257 WeakPolarHBondContact O-CB 3.39Å; Y253-K257 PolarHBondContact O-N 3.22Å; E254-K257 PolarHBondContact O-N 3.42Å; L255-K257 VanDerWaalsContact C-N 3.3Å; L255-K257 PolarHBondContact O-N 3.36Å; K257-S260 PolarHBondContact O-OG 3.46Å; K257-S260 VanDerWaalsContact O-OG 3.11Å; K257-K261 PolarHBondContact O-N 2.82Å
258	Q	88.6	Confident	80.6	Confident	96 Å²	96	65.8 Å²	65.8	45%	0.449	35%	0.353	S	S	.	.	H	α-helix	trans	-63.5	-44.2	177	-175.5	-179.5	6.9	0	0	111.5	E254 L255 K261	E254-Q258 PolarHBondContact O-N 2.83Å; L255-Q258 PolarHBondContact O-N 3.44Å; Q258-K261 WeakPolarHBondContact O-CB 3.12Å
259	L	89.7	Confident	80.7	Confident	0 Å²	0	63.1 Å²	63.1	0%	0	33%	0.334	C	S	.	.	H	α-helix	trans	-67.6	-44.7	179.2	-71	176.3	0	0	0	112.1	V242 F243 L255 L256 K261 H262 N325 L328 A329	V242-L259 HydrophobicContact CB-CD2 4.38Å; V242-L259 HydrophobicContact CG1-CD2 3.74Å; F243-L259 HydrophobicContact CD1-CD2 4.31Å; F243-L259 HydrophobicContact CD2-CD2 3.91Å; F243-L259 HydrophobicContact CE1-CD2 4.12Å; F243-L259 HydrophobicContact CE2-CD2 3.71Å; F243-L259 HydrophobicContact CG-CD2 4.22Å; F243-L259 HydrophobicContact CZ-CB 4.3Å; F243-L259 HydrophobicContact CZ-CD2 3.82Å; L255-L259 HydrophobicContact CD1-CD1 4.17Å; L255-L259 HydrophobicContact CD1-CG 4.15Å; L255-L259 HydrophobicContact CD2-CD1 4.45Å; L255-L259 HydrophobicContact CG-CD1 3.93Å; L255-L259 HydrophobicContact CG-CG 4.29Å; L255-L259 WeakPolarHBondContact O-CB 3.36Å; L255-L259 WeakPolarHBondContact O-CG 3.36Å; L255-L259 PolarHBondContact O-N 3.47Å; L256-L259 PolarHBondContact O-N 3.24Å; L259-K261 PolarHBondContact O-N 3.28Å; L259-H262 PolarHBondContact O-N 2.95Å; L259-N325 HydrophobicContact CD1-CB 4.24Å; L259-N325 HydrophobicContact CD2-CB 4.28Å; L259-L328 HydrophobicContact CD1-CB 4.02Å; L259-L328 HydrophobicContact CD1-CD1 4.33Å; L259-A329 HydrophobicContact CB-CB 3.86Å
260	S	87.7	Confident	81.1	Confident	13 Å²	13	60 Å²	60	9%	0.091	32%	0.318	C	S	.	.	H	α-helix	trans	-65	-27.1	-178.8	64	0	0	0	0	113.4	L256 K257 H262 I263 T264 K332	L256-S260 WeakPolarHBondContact O-CB 3.43Å; L256-S260 PolarHBondContact O-N 3.23Å; L256-S260 PolarHBondContact O-OG 3.3Å; K257-S260 PolarHBondContact O-OG 3.46Å; K257-S260 VanDerWaalsContact O-OG 3.11Å; S260-H262 PolarHBondContact O-N 2.89Å; S260-I263 PolarHBondContact O-N 3.27Å; S260-T264 PolarHBondContact O-N 3.27Å; S260-T264 PolarHBondContact O-OG1 3.17Å; S260-K332 VanDerWaalsContact CB-CG 3.45Å; S260-K332 WeakPolarHBondContact OG-CG 3.43Å
261	K	88	Confident	81.4	Confident	100 Å²	100	61.8 Å²	61.8	44%	0.435	33%	0.329	S	S	.	.	H	α-helix	trans	-52.3	-40.5	176.3	-168.7	-175.4	175.2	-169	0	111.5	K257 Q258 L259 I263 T264 D265	K257-K261 PolarHBondContact O-N 2.82Å; Q258-K261 WeakPolarHBondContact O-CB 3.12Å; L259-K261 PolarHBondContact O-N 3.28Å; K261-I263 PolarHBondContact O-N 2.96Å; K261-T264 PolarHBondContact O-N 2.89Å; K261-D265 WeakPolarHBondContact CE-OD2 3.24Å; K261-D265 HydrophobicContact CG-CB 4.36Å; K261-D265 WeakPolarHBondContact CG-OD1 3.34Å; K261-D265 WeakPolarHBondContact CG-OD2 3.15Å; K261-D265 IonicContact NZ-OD2 3.54Å; K261-D265 VanDerWaalsContact O-CB 3.22Å; K261-D265 WeakPolarHBondContact O-CB 3.38Å; K261-D265 PolarHBondContact O-N 3.39Å
262	H	86.2	Confident	82	Confident	34 Å²	34	63.3 Å²	63.3	16%	0.157	34%	0.337	C	S	.	.	H	α-helix	trans	-72	-4.8	178.8	-66.6	-68.4	0	0	0	114.7	P240 F243 L259 S260 S269 L270	P240-H262 HydrophobicContact CG-CB 4.11Å; F243-H262 HydrophobicContact CE2-CB 4.03Å; F243-H262 AromaticContact CE2-CD2 3.87Å; F243-H262 HydrophobicContact CZ-CB 4.35Å; L259-H262 PolarHBondContact O-N 2.95Å; S260-H262 PolarHBondContact O-N 2.89Å; H262-S269 WeakPolarHBondContact O-CA 3.4Å; H262-L270 HydrophobicContact CB-CG 4.43Å; H262-L270 WeakPolarHBondContact O-CG 3.37Å; H262-L270 PolarHBondContact O-N 2.9Å
263	I	84.2	Confident	82.2	Confident	24 Å²	24	65.6 Å²	65.6	12%	0.123	35%	0.347	C	S	.	.	H	α-helix	trans	-105.1	-37.5	172.6	-59.2	178.9	0	0	0	110.4	S260 K261 A329 I330 V333 L382	S260-I263 PolarHBondContact O-N 3.27Å; K261-I263 PolarHBondContact O-N 2.96Å; I263-A329 HydrophobicContact CD1-CB 3.47Å; I263-A329 VanDerWaalsContact CD1-CB 3.47Å; I263-A329 HydrophobicContact CG1-CB 4.31Å; I263-I330 HydrophobicContact CD1-CG1 3.83Å; I263-V333 HydrophobicContact CB-CG2 3.96Å; I263-V333 HydrophobicContact CD1-CG2 4.27Å; I263-V333 HydrophobicContact CG2-CG2 3.89Å; I263-L382 HydrophobicContact CG2-CD1 3.81Å; I263-L382 HydrophobicContact CG2-CD2 4.17Å
264	T	79.1	Confident	82.4	Confident	83 Å²	83	62.8 Å²	62.8	51%	0.509	34%	0.336	S	S	.	.	H	α-helix	trans	-90.7	-28	-172.4	55	0	0	0	0	114.7	S260 K261 V333	S260-T264 PolarHBondContact O-N 3.27Å; S260-T264 PolarHBondContact O-OG1 3.17Å; K261-T264 PolarHBondContact O-N 2.89Å; T264-V333 HydrophobicContact CG2-CG1 4.26Å; T264-V333 HydrophobicContact CG2-CG2 3.83Å
265	D	73.7	Confident	82.6	Confident	55 Å²	55	56 Å²	56	29%	0.294	31%	0.305	S	S	.	.			trans	-79.1	129	-172.9	-74.7	21.4	0	0	0	110.9	K261 D267 S269	K261-D265 WeakPolarHBondContact CE-OD2 3.24Å; K261-D265 HydrophobicContact CG-CB 4.36Å; K261-D265 WeakPolarHBondContact CG-OD1 3.34Å; K261-D265 WeakPolarHBondContact CG-OD2 3.15Å; K261-D265 IonicContact NZ-OD2 3.54Å; K261-D265 VanDerWaalsContact O-CB 3.22Å; K261-D265 WeakPolarHBondContact O-CB 3.38Å; K261-D265 PolarHBondContact O-N 3.39Å; D265-D267 PolarHBondContact O-N 3.16Å; D265-S269 WeakPolarHBondContact O-CA 3.25Å; D265-S269 WeakPolarHBondContact O-CB 3.2Å; D265-S269 PolarHBondContact O-N 3.38Å
266	A	66.3	Low	82.8	Confident	87 Å²	87	56.4 Å²	56.4	72%	0.719	31%	0.309	S	S	*	.	S	Bend	trans	-59.9	-43.3	-177.5	0	0	0	0	0	112.8	S269	A266-S269 PolarHBondContact O-OG 2.99Å
267	D	67.9	Low	82.9	Confident	161 Å²	161	56.9 Å²	56.9	86%	0.861	31%	0.312	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80	-32.5	-171.5	-61.4	-31	0	0	0	113.6	D265	D265-D267 PolarHBondContact O-N 3.16Å
268	D	66.5	Low	83.2	Confident	99 Å²	99	50.6 Å²	50.6	53%	0.529	28%	0.284	S	S	.	.	T	Hydrogen-bonded Turn	trans	-112.6	19	-176.7	-76.6	-27.3	0	0	0	112.5
269	S	76.5	Confident	83.4	Confident	64 Å²	64	46.2 Å²	46.2	45%	0.448	26%	0.264	S	S	.	.			trans	-67.4	137.1	-177.5	49.9	0	0	0	0	112.3	H262 D265 A266 N271	H262-S269 WeakPolarHBondContact O-CA 3.4Å; D265-S269 WeakPolarHBondContact O-CA 3.25Å; D265-S269 WeakPolarHBondContact O-CB 3.2Å; D265-S269 PolarHBondContact O-N 3.38Å; A266-S269 PolarHBondContact O-OG 2.99Å; S269-N271 PolarHBondContact O-N 3.09Å
270	L	84	Confident	83.4	Confident	17 Å²	17	48 Å²	48	9%	0.089	27%	0.274	C	S	.	.			trans	-60.4	129.2	164.9	-74.2	173.1	0	0	0	110.1	L238 P240 F243 H262 L272 L326	L238-L270 WeakPolarHBondContact O-CD2 3.33Å; P240-L270 HydrophobicContact CG-CD2 4.41Å; F243-L270 HydrophobicContact CZ-CD1 4.35Å; H262-L270 HydrophobicContact CB-CG 4.43Å; H262-L270 WeakPolarHBondContact O-CG 3.37Å; H262-L270 PolarHBondContact O-N 2.9Å; L270-L272 HydrophobicContact CB-CD2 4.08Å; L270-L272 PolarHBondContact O-N 3.09Å; L270-L326 HydrophobicContact CD1-CD2 4.17Å
271	N	85	Confident	83.7	Confident	68 Å²	68	47.4 Å²	47.4	36%	0.364	27%	0.269	S	S	.	.			trans	-73.7	94.3	166.5	-170.5	-39.7	0	0	0	109.5	S269 D273 I274 L275	S269-N271 PolarHBondContact O-N 3.09Å; N271-D273 VanDerWaalsContact C-N 3.28Å; N271-D273 PolarHBondContact O-N 2.63Å; N271-D273 PolarHBondContact OD1-N 3.36Å; N271-I274 HydrophobicContact CB-CB 4.18Å; N271-I274 HydrophobicContact CB-CD1 4.06Å; N271-I274 HydrophobicContact CB-CG1 4.23Å; N271-I274 VanDerWaalsContact ND2-CD1 3.27Å; N271-I274 WeakPolarHBondContact ND2-CD1 3.37Å; N271-I274 PolarHBondContact O-N 3.1Å; N271-I274 WeakPolarHBondContact OD1-CG1 3.35Å; N271-I274 PolarHBondContact OD1-N 3.49Å; N271-L275 WeakPolarHBondContact O-CB 3.42Å; N271-L275 PolarHBondContact O-N 3.2Å
272	L	86.8	Confident	83.9	Confident	32 Å²	32	42.7 Å²	42.7	17%	0.168	25%	0.249	C	C	.	.	H	α-helix	trans	-61.5	-33.7	-175.4	-59.8	-177.3	0	0	0	112.8	L270 L275 S276 L382 F385	L270-L272 HydrophobicContact CB-CD2 4.08Å; L270-L272 PolarHBondContact O-N 3.09Å; L272-L275 PolarHBondContact O-N 3.29Å; L272-S276 VanDerWaalsContact O-CB 3.22Å; L272-S276 WeakPolarHBondContact O-CB 3.35Å; L272-S276 PolarHBondContact O-N 2.94Å; L272-L382 HydrophobicContact CD1-CB 4.44Å; L272-L382 HydrophobicContact CD1-CD1 3.76Å; L272-F385 HydrophobicContact CB-CB 4.14Å; L272-F385 HydrophobicContact CB-CD2 3.81Å; L272-F385 HydrophobicContact CB-CE2 4.45Å; L272-F385 HydrophobicContact CB-CG 3.94Å; L272-F385 HydrophobicContact CD1-CB 4.19Å; L272-F385 HydrophobicContact CD1-CD1 4.45Å; L272-F385 HydrophobicContact CD1-CG 4.28Å; L272-F385 HydrophobicContact CD2-CD1 3.91Å; L272-F385 HydrophobicContact CD2-CD2 4.23Å; L272-F385 HydrophobicContact CD2-CE1 3.97Å; L272-F385 HydrophobicContact CD2-CE2 4.33Å; L272-F385 HydrophobicContact CD2-CG 4.05Å; L272-F385 HydrophobicContact CD2-CZ 4.21Å; L272-F385 HydrophobicContact CG-CG 4.31Å; L272-F385 VanDerWaalsContact O-CD2 3.3Å; L272-F385 WeakPolarHBondContact O-CD2 3.32Å
273	D	86.5	Confident	84.2	Confident	95 Å²	95	41.1 Å²	41.1	51%	0.508	24%	0.242	S	C	.	.	H	α-helix	trans	-71.3	-43.1	179.4	-74	-26.9	0	0	0	111.9	I192 N271 L275 S277	I192-D273 HydrophobicContact CD1-CB 3.47Å; I192-D273 VanDerWaalsContact CD1-CB 3.47Å; I192-D273 HydrophobicContact CG1-CB 4.2Å; N271-D273 VanDerWaalsContact C-N 3.28Å; N271-D273 PolarHBondContact O-N 2.63Å; N271-D273 PolarHBondContact OD1-N 3.36Å; D273-L275 VanDerWaalsContact C-N 3.35Å; D273-S277 WeakPolarHBondContact O-CB 3.23Å; D273-S277 PolarHBondContact O-N 3.32Å; D273-S277 PolarHBondContact O-OG 2.95Å
274	I	87.9	Confident	84.4	Confident	3 Å²	3	41 Å²	41	2%	0.015	24%	0.241	C	C	.	.	H	α-helix	trans	-63.8	-44.8	174	-64.1	176.5	0	0	0	109.5	T191 I192 L238 N271 S277 H278	T191-I274 HydrophobicContact CG2-CD1 4.32Å; T191-I274 HydrophobicContact CG2-CG1 4.46Å; T191-I274 HydrophobicContact CG2-CG2 4.06Å; I192-I274 HydrophobicContact CD1-CG1 4.13Å; I192-I274 HydrophobicContact CG1-CG1 3.63Å; L238-I274 HydrophobicContact CD1-CG2 3.63Å; L238-I274 HydrophobicContact CD2-CG2 4.14Å; N271-I274 HydrophobicContact CB-CB 4.18Å; N271-I274 HydrophobicContact CB-CD1 4.06Å; N271-I274 HydrophobicContact CB-CG1 4.23Å; N271-I274 VanDerWaalsContact ND2-CD1 3.27Å; N271-I274 WeakPolarHBondContact ND2-CD1 3.37Å; N271-I274 PolarHBondContact O-N 3.1Å; N271-I274 WeakPolarHBondContact OD1-CG1 3.35Å; N271-I274 PolarHBondContact OD1-N 3.49Å; I274-S277 WeakPolarHBondContact CA-OG 3.5Å; I274-S277 PolarHBondContact O-N 3.39Å; I274-S277 PolarHBondContact O-OG 3.38Å; I274-H278 PolarHBondContact O-N 2.84Å; I274-H278 PolarHBondContact O-ND1 3.33Å
275	L	90.9	Very high	84.8	Confident	1 Å²	1	37.3 Å²	37.3	1%	0.005	22%	0.218	C	C	.	.	H	α-helix	trans	-61.6	-47.2	178.8	-176.1	59.1	0	0	0	111.7	L235 L239 N271 L272 D273 S277 H278 L279 L326 F385	L235-L275 HydrophobicContact CD2-CD1 3.6Å; L239-L275 HydrophobicContact CD2-CD1 4.19Å; L239-L275 HydrophobicContact CD2-CD2 4.03Å; L239-L275 HydrophobicContact CG-CD1 4.37Å; N271-L275 WeakPolarHBondContact O-CB 3.42Å; N271-L275 PolarHBondContact O-N 3.2Å; L272-L275 PolarHBondContact O-N 3.29Å; D273-L275 VanDerWaalsContact C-N 3.35Å; L275-S277 PolarHBondContact O-N 3.27Å; L275-H278 PolarHBondContact O-N 3.47Å; L275-L279 HydrophobicContact CD1-CD1 4.23Å; L275-L279 HydrophobicContact CD1-CG 4.24Å; L275-L279 HydrophobicContact CG-CD1 4.05Å; L275-L279 HydrophobicContact CG-CG 4.47Å; L275-L279 WeakPolarHBondContact O-CB 3.18Å; L275-L279 VanDerWaalsContact O-CG 3.29Å; L275-L279 WeakPolarHBondContact O-CG 3.26Å; L275-L279 PolarHBondContact O-N 2.84Å; L275-L326 HydrophobicContact CD2-CD1 4.27Å; L275-L326 HydrophobicContact CD2-CD2 4.03Å; L275-F385 HydrophobicContact CB-CE2 4.06Å; L275-F385 HydrophobicContact CD2-CE2 3.85Å; L275-F385 HydrophobicContact CD2-CZ 3.53Å; L275-F385 HydrophobicContact CG-CE2 3.9Å; L275-F385 HydrophobicContact CG-CZ 4.03Å
276	S	89.8	Confident	85.6	Confident	19 Å²	19	34.7 Å²	34.7	13%	0.133	20%	0.204	C	C	.	.	H	α-helix	trans	-59.4	-46.2	177.2	177.2	0	0	0	0	112.5	L272 H278 L279 N280	L272-S276 VanDerWaalsContact O-CB 3.22Å; L272-S276 WeakPolarHBondContact O-CB 3.35Å; L272-S276 PolarHBondContact O-N 2.94Å; S276-H278 VanDerWaalsContact C-N 3.33Å; S276-H278 PolarHBondContact O-N 3.31Å; S276-L279 PolarHBondContact O-N 2.9Å; S276-N280 WeakPolarHBondContact O-CB 3.46Å; S276-N280 PolarHBondContact O-N 2.91Å; S276-N280 PolarHBondContact O-ND2 2.71Å
277	S	89.3	Confident	86.5	Confident	10 Å²	10	34.5 Å²	34.5	7%	0.07	19%	0.19	C	C	.	.	H	α-helix	trans	-63.3	-39.1	178.7	55.3	0	0	0	0	112.3	T195 D273 I274 L275 L281	T195-S277 VanDerWaalsContact CG2-C 3.48Å; T195-S277 VanDerWaalsContact CG2-O 3.32Å; T195-S277 WeakPolarHBondContact CG2-O 3.46Å; D273-S277 WeakPolarHBondContact O-CB 3.23Å; D273-S277 PolarHBondContact O-N 3.32Å; D273-S277 PolarHBondContact O-OG 2.95Å; I274-S277 WeakPolarHBondContact CA-OG 3.5Å; I274-S277 PolarHBondContact O-N 3.39Å; I274-S277 PolarHBondContact O-OG 3.38Å; L275-S277 PolarHBondContact O-N 3.27Å; S277-L281 WeakPolarHBondContact O-CB 3.26Å; S277-L281 PolarHBondContact O-N 2.78Å
278	H	93.1	Very high	87.2	Confident	1 Å²	1	31.8 Å²	31.8	1%	0.005	17%	0.167	C	C	.	.	H	α-helix	trans	-72.6	-38.1	177.5	-76.4	77	0	0	0	113.2	S182 T195 V234 L235 I274 L275 S276 N280 L281 L282	S182-H278 PolarHBondContact O-NE2 3.36Å; T195-H278 PolarHBondContact OG1-CE1 3.45Å; V234-H278 WeakPolarHBondContact CG1-NE2 3.17Å; L235-H278 HydrophobicContact CD2-CB 3.55Å; L235-H278 HydrophobicContact CG-CB 3.98Å; I274-H278 PolarHBondContact O-N 2.84Å; I274-H278 PolarHBondContact O-ND1 3.33Å; L275-H278 PolarHBondContact O-N 3.47Å; S276-H278 VanDerWaalsContact C-N 3.33Å; S276-H278 PolarHBondContact O-N 3.31Å; H278-N280 VanDerWaalsContact C-N 3.33Å; H278-L281 PolarHBondContact O-N 2.89Å; H278-L282 WeakPolarHBondContact O-CB 3.25Å; H278-L282 PolarHBondContact O-N 3.13Å
279	L	92.3	Very high	87.9	Confident	4 Å²	4	27.5 Å²	27.5	2%	0.021	14%	0.144	C	C	.	.	H	α-helix	trans	-64.2	-40.7	174.5	-71.6	174.2	0	0	0	111.4	L235 L275 S276 L282 T283 F323 L389	L235-L279 HydrophobicContact CD1-CD2 4.19Å; L235-L279 HydrophobicContact CD2-CD2 3.94Å; L235-L279 HydrophobicContact CD2-CG 4.08Å; L275-L279 HydrophobicContact CD1-CD1 4.23Å; L275-L279 HydrophobicContact CD1-CG 4.24Å; L275-L279 HydrophobicContact CG-CD1 4.05Å; L275-L279 HydrophobicContact CG-CG 4.47Å; L275-L279 WeakPolarHBondContact O-CB 3.18Å; L275-L279 VanDerWaalsContact O-CG 3.29Å; L275-L279 WeakPolarHBondContact O-CG 3.26Å; L275-L279 PolarHBondContact O-N 2.84Å; S276-L279 PolarHBondContact O-N 2.9Å; L279-L282 PolarHBondContact O-N 3.16Å; L279-T283 WeakPolarHBondContact O-CB 3.42Å; L279-T283 PolarHBondContact O-N 3.42Å; L279-T283 PolarHBondContact O-OG1 2.75Å; L279-F323 HydrophobicContact CD2-CE1 4.37Å; L279-F323 HydrophobicContact CD2-CE2 4.46Å; L279-F323 HydrophobicContact CD2-CZ 3.84Å; L279-L389 HydrophobicContact CD1-CD1 3.6Å
280	N	90.9	Very high	87.8	Confident	38 Å²	38	25.6 Å²	25.6	20%	0.203	13%	0.13	C	C	.	.	H	α-helix	trans	-62	-45	173.4	-86.5	-40.1	0	0	0	111.7	S276 H278 T283 I284 E388 S392	S276-N280 WeakPolarHBondContact O-CB 3.46Å; S276-N280 PolarHBondContact O-N 2.91Å; S276-N280 PolarHBondContact O-ND2 2.71Å; H278-N280 VanDerWaalsContact C-N 3.33Å; N280-T283 PolarHBondContact O-N 3.36Å; N280-I284 WeakPolarHBondContact O-CG1 3.47Å; N280-I284 PolarHBondContact O-N 3.03Å; N280-I284 VanDerWaalsContact O-N 3.15Å; N280-E388 PolarHBondContact ND2-OE2 3.49Å; N280-E388 VanDerWaalsContact ND2-OE2 3.07Å; N280-S392 PolarHBondContact OD1-OG 3.3Å
281	L	93	Very high	87.3	Confident	0 Å²	0	25.3 Å²	25.3	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-62.2	-46.7	176	-179.7	59	0	0	0	111.8	T195 L198 L202 V231 S277 H278 T283 I284 I285	T195-L281 HydrophobicContact CG2-CB 3.98Å; T195-L281 HydrophobicContact CG2-CD2 3.77Å; T195-L281 HydrophobicContact CG2-CG 4.5Å; L198-L281 HydrophobicContact CB-CD1 4.25Å; L198-L281 HydrophobicContact CB-CD2 4.2Å; L198-L281 HydrophobicContact CD1-CD2 4.15Å; L202-L281 HydrophobicContact CD1-CD1 3.36Å; L202-L281 HydrophobicContact CG-CD1 4.47Å; V231-L281 HydrophobicContact CG2-CD2 3.57Å; V231-L281 HydrophobicContact CG2-CG 4Å; S277-L281 WeakPolarHBondContact O-CB 3.26Å; S277-L281 PolarHBondContact O-N 2.78Å; H278-L281 PolarHBondContact O-N 2.89Å; L281-T283 VanDerWaalsContact C-N 3.29Å; L281-T283 PolarHBondContact O-N 3.35Å; L281-I284 PolarHBondContact O-N 2.88Å; L281-I285 HydrophobicContact CD1-CD1 4.26Å; L281-I285 HydrophobicContact CD1-CG1 4.49Å; L281-I285 HydrophobicContact CG-CD1 4.01Å; L281-I285 WeakPolarHBondContact O-CG1 3.32Å; L281-I285 PolarHBondContact O-N 3.43Å
282	L	93.1	Very high	87	Confident	1 Å²	1	22.3 Å²	22.3	1%	0.005	11%	0.114	C	C	.	.	H	α-helix	trans	-56.5	-44.6	176	178.6	64.5	0	0	0	111.3	F228 V231 V232 L235 H278 L279 I284 I285 L286	F228-L282 HydrophobicContact CD2-CD1 4.25Å; F228-L282 HydrophobicContact CE2-CD1 3.97Å; V231-L282 HydrophobicContact CG1-CB 3.8Å; V231-L282 HydrophobicContact CG1-CD1 4.21Å; V232-L282 HydrophobicContact CG2-CD1 4.34Å; L235-L282 HydrophobicContact CD1-CB 4.08Å; L235-L282 HydrophobicContact CD1-CD2 3.54Å; L235-L282 HydrophobicContact CD1-CG 4.31Å; H278-L282 WeakPolarHBondContact O-CB 3.25Å; H278-L282 PolarHBondContact O-N 3.13Å; L279-L282 PolarHBondContact O-N 3.16Å; L282-I284 VanDerWaalsContact C-N 3.33Å; L282-I284 PolarHBondContact O-N 3.09Å; L282-I285 PolarHBondContact O-N 3.08Å; L282-L286 HydrophobicContact CD1-CD1 3.85Å; L282-L286 HydrophobicContact CD1-CG 4.21Å; L282-L286 HydrophobicContact CD2-CD1 4.31Å; L282-L286 HydrophobicContact CG-CD1 3.7Å; L282-L286 HydrophobicContact CG-CG 4.46Å; L282-L286 WeakPolarHBondContact O-CG 3.21Å; L282-L286 PolarHBondContact O-N 3.43Å
283	T	90.7	Very high	86.6	Confident	2 Å²	2	25.4 Å²	25.4	1%	0.012	13%	0.128	C	C	.	.	H	α-helix	trans	-59.9	-43	179.4	-57.5	0	0	0	0	111.4	L279 N280 L281 L286 M287 N395 L396	L279-T283 WeakPolarHBondContact O-CB 3.42Å; L279-T283 PolarHBondContact O-N 3.42Å; L279-T283 PolarHBondContact O-OG1 2.75Å; N280-T283 PolarHBondContact O-N 3.36Å; L281-T283 VanDerWaalsContact C-N 3.29Å; L281-T283 PolarHBondContact O-N 3.35Å; T283-L286 PolarHBondContact O-N 3.09Å; T283-M287 HydrophobicContact CG2-CE 3.97Å; T283-M287 HydrophobicContact CG2-CG 4.49Å; T283-M287 HydrophobicContact CG2-SD 4.27Å; T283-M287 WeakPolarHBondContact O-CB 3.4Å; T283-M287 VanDerWaalsContact O-CG 3.28Å; T283-M287 WeakPolarHBondContact O-CG 3.46Å; T283-M287 PolarHBondContact O-N 3.42Å; T283-N395 HydrophobicContact CG2-CB 3.45Å; T283-N395 VanDerWaalsContact CG2-CB 3.45Å; T283-L396 HydrophobicContact CG2-CD2 4.24Å; T283-L396 HydrophobicContact CG2-CG 4.39Å
284	I	88.6	Confident	86.1	Confident	22 Å²	22	24.6 Å²	24.6	11%	0.113	13%	0.126	C	C	.	.	H	α-helix	trans	-66.5	-43	177.6	-67.7	169.6	0	0	0	111.4	T199 L202 F206 N280 L281 L282 L286 M287 R288	T199-I284 HydrophobicContact CG2-CD1 3.36Å; L202-I284 HydrophobicContact CB-CG2 4.3Å; L202-I284 HydrophobicContact CD1-CG2 4.09Å; F206-I284 HydrophobicContact CE2-CG2 4.21Å; N280-I284 WeakPolarHBondContact O-CG1 3.47Å; N280-I284 PolarHBondContact O-N 3.03Å; N280-I284 VanDerWaalsContact O-N 3.15Å; L281-I284 PolarHBondContact O-N 2.88Å; L282-I284 VanDerWaalsContact C-N 3.33Å; L282-I284 PolarHBondContact O-N 3.09Å; I284-L286 VanDerWaalsContact C-N 3.33Å; I284-L286 PolarHBondContact O-N 2.77Å; I284-M287 HydrophobicContact CG1-CE 4.34Å; I284-M287 PolarHBondContact O-N 2.85Å; I284-R288 PolarHBondContact O-N 3.4Å; I284-R288 VanDerWaalsContact O-N 3.15Å
285	I	89	Confident	85.5	Confident	4 Å²	4	26.4 Å²	26.4	2%	0.021	14%	0.136	C	C	.	.	H	α-helix	trans	-57.8	-48.6	177.1	-68.4	165.8	0	0	0	109.9	L202 L227 F228 V231 L281 L282 R288 L289 V292	L202-I285 HydrophobicContact CD1-CG1 3.87Å; L227-I285 HydrophobicContact CD2-CD1 4.01Å; L227-I285 HydrophobicContact CD2-CG1 4.28Å; L227-I285 HydrophobicContact CG-CD1 3.86Å; F228-I285 HydrophobicContact CB-CG2 4.27Å; F228-I285 HydrophobicContact CD2-CG2 3.99Å; V231-I285 HydrophobicContact CB-CD1 4.35Å; V231-I285 HydrophobicContact CG2-CD1 3.86Å; L281-I285 HydrophobicContact CD1-CD1 4.26Å; L281-I285 HydrophobicContact CD1-CG1 4.49Å; L281-I285 HydrophobicContact CG-CD1 4.01Å; L281-I285 WeakPolarHBondContact O-CG1 3.32Å; L281-I285 PolarHBondContact O-N 3.43Å; L282-I285 PolarHBondContact O-N 3.08Å; I285-R288 PolarHBondContact O-N 3.17Å; I285-L289 HydrophobicContact CG2-CB 4.3Å; I285-L289 HydrophobicContact CG2-CD2 4.27Å; I285-L289 WeakPolarHBondContact O-CB 3.48Å; I285-L289 PolarHBondContact O-N 3.11Å; I285-V292 HydrophobicContact CG2-CG2 4.03Å
286	L	88.8	Confident	84.9	Confident	1 Å²	1	26.5 Å²	26.5	1%	0.005	14%	0.136	C	C	.	.	H	α-helix	trans	-65.9	-43.5	179.4	-66.8	162.9	0	0	0	111.6	F228 L282 T283 I284 R288 V292 L296 F315 L396 I399 Y401 L402	F228-L286 HydrophobicContact CE2-CD2 4.22Å; L282-L286 HydrophobicContact CD1-CD1 3.85Å; L282-L286 HydrophobicContact CD1-CG 4.21Å; L282-L286 HydrophobicContact CD2-CD1 4.31Å; L282-L286 HydrophobicContact CG-CD1 3.7Å; L282-L286 HydrophobicContact CG-CG 4.46Å; L282-L286 WeakPolarHBondContact O-CG 3.21Å; L282-L286 PolarHBondContact O-N 3.43Å; T283-L286 PolarHBondContact O-N 3.09Å; I284-L286 VanDerWaalsContact C-N 3.33Å; I284-L286 PolarHBondContact O-N 2.77Å; L286-R288 PolarHBondContact O-N 3.23Å; L286-V292 HydrophobicContact CD2-CG1 3.52Å; L286-L296 HydrophobicContact CD2-CD1 3.38Å; L286-F315 HydrophobicContact CD1-CE2 3.91Å; L286-F315 HydrophobicContact CD1-CZ 4.32Å; L286-F315 HydrophobicContact CD2-CE2 3.99Å; L286-F315 HydrophobicContact CD2-CZ 4Å; L286-L396 HydrophobicContact CB-CD2 4.25Å; L286-L396 HydrophobicContact CD1-CD2 3.39Å; L286-L396 HydrophobicContact CG-CD2 4.44Å; L286-I399 HydrophobicContact CB-CD1 3.73Å; L286-Y401 VanDerWaalsContact C-OH 3.25Å; L286-Y401 WeakPolarHBondContact CA-OH 3.12Å; L286-Y401 PolarHBondContact O-OH 2.72Å; L286-L402 HydrophobicContact CB-CD1 4.45Å; L286-L402 HydrophobicContact CD1-CD1 4.17Å; L286-L402 HydrophobicContact CD2-CD1 4.47Å; L286-L402 HydrophobicContact CD2-CD2 4.46Å
287	M	85.2	Confident	84.1	Confident	83 Å²	83	28.8 Å²	28.8	41%	0.409	15%	0.152	S	C	.	.	H	α-helix	trans	-65.2	-25.4	-178.7	-74.8	-171.3	-55.1	0	0	114.2	T283 I284 N395 I399	T283-M287 HydrophobicContact CG2-CE 3.97Å; T283-M287 HydrophobicContact CG2-CG 4.49Å; T283-M287 HydrophobicContact CG2-SD 4.27Å; T283-M287 WeakPolarHBondContact O-CB 3.4Å; T283-M287 VanDerWaalsContact O-CG 3.28Å; T283-M287 WeakPolarHBondContact O-CG 3.46Å; T283-M287 PolarHBondContact O-N 3.42Å; I284-M287 HydrophobicContact CG1-CE 4.34Å; I284-M287 PolarHBondContact O-N 2.85Å; M287-N395 HydrophobicContact SD-CB 4.01Å; M287-I399 HydrophobicContact CB-CD1 4.43Å; M287-I399 HydrophobicContact CG-CD1 3.65Å; M287-I399 HydrophobicContact CG-CG1 4.04Å
288	R	83.1	Confident	83	Confident	103 Å²	103	30.6 Å²	30.6	39%	0.389	17%	0.165	S	C	.	.	H	α-helix	trans	-130	-15	-164.7	-63.6	-168.5	175.9	-176.5	3.2	116.4	N203 F206 I284 I285 L286 P290	N203-R288 PolarHBondContact OD1-NH1 3.05Å; F206-R288 HydrophobicContact CD1-CB 4.16Å; F206-R288 HydrophobicContact CD2-CB 3.89Å; F206-R288 HydrophobicContact CD2-CG 4.27Å; F206-R288 HydrophobicContact CE1-CB 3.78Å; F206-R288 WeakPolarHBondContact CE1-O 3.33Å; F206-R288 HydrophobicContact CE2-CB 3.48Å; F206-R288 VanDerWaalsContact CE2-CB 3.48Å; F206-R288 HydrophobicContact CE2-CG 4.24Å; F206-R288 HydrophobicContact CG-CB 4.22Å; F206-R288 HydrophobicContact CZ-CB 3.43Å; F206-R288 VanDerWaalsContact CZ-CB 3.43Å; I284-R288 PolarHBondContact O-N 3.4Å; I284-R288 VanDerWaalsContact O-N 3.15Å; I285-R288 PolarHBondContact O-N 3.17Å; L286-R288 PolarHBondContact O-N 3.23Å; R288-P290 WeakPolarHBondContact O-CD 3.37Å
289	L	80.9	Confident	81.2	Confident	10 Å²	10	36.9 Å²	36.9	5%	0.052	20%	0.203	C	C	.	.			trans	-92.1	112.4	-177.3	-158.1	81.2	0	0	0	111.2	F206 V220 M222 I285 S291 V292 Q293	F206-L289 HydrophobicContact CZ-CD1 4.41Å; V220-L289 HydrophobicContact CG1-CD1 4.43Å; M222-L289 HydrophobicContact CB-CD1 4.16Å; M222-L289 HydrophobicContact CE-CD1 3.56Å; M222-L289 HydrophobicContact CG-CD1 4.43Å; M222-L289 HydrophobicContact SD-CD1 3.41Å; M222-L289 WeakPolarHBondContact SD-CD1 3.47Å; I285-L289 HydrophobicContact CG2-CB 4.3Å; I285-L289 HydrophobicContact CG2-CD2 4.27Å; I285-L289 WeakPolarHBondContact O-CB 3.48Å; I285-L289 PolarHBondContact O-N 3.11Å; L289-S291 WeakPolarHBondContact CD2-OG 3.36Å; L289-S291 VanDerWaalsContact CG-OG 3.32Å; L289-S291 WeakPolarHBondContact CG-OG 3.35Å; L289-S291 PolarHBondContact O-N 3.36Å; L289-V292 HydrophobicContact CB-CB 4.36Å; L289-V292 HydrophobicContact CD2-CB 4.25Å; L289-V292 HydrophobicContact CD2-CG2 3.63Å; L289-V292 PolarHBondContact O-N 3.29Å; L289-Q293 PolarHBondContact O-N 3.25Å; L289-Q293 VanDerWaalsContact O-N 3.16Å
290	P	74.2	Confident	79.2	Confident	23 Å²	23	42.3 Å²	42.3	15%	0.149	24%	0.237	C	C	.	.	H	α-helix	trans	-63.9	-30.9	-178.8	-21.2	33.7	0	0	0	112.7	C213 R288 Q293 V294	C213-P290 VanDerWaalsContact C-CG 3.47Å; C213-P290 VanDerWaalsContact CA-CG 3.46Å; C213-P290 HydrophobicContact CB-CG 4.44Å; C213-P290 WeakPolarHBondContact O-CG 3.41Å; R288-P290 WeakPolarHBondContact O-CD 3.37Å; P290-Q293 CarbonylContact O-C 3.43Å; P290-Q293 WeakPolarHBondContact O-CB 3.2Å; P290-Q293 PolarHBondContact O-N 2.83Å; P290-V294 WeakPolarHBondContact O-CG2 3.45Å; P290-V294 PolarHBondContact O-N 2.96Å
291	S	74.6	Confident	77.3	Confident	12 Å²	12	44.2 Å²	44.2	8%	0.084	25%	0.253	C	S	.	.	H	α-helix	trans	-66.9	-40.5	-178.9	45.1	0	0	0	0	113.9	Y216 E223 L289 Q293 V294 L295	Y216-S291 VanDerWaalsContact CZ-CA 3.5Å; Y216-S291 WeakPolarHBondContact OH-CA 3.47Å; Y216-S291 WeakPolarHBondContact OH-CB 3.46Å; E223-S291 WeakPolarHBondContact OE1-CB 3.36Å; E223-S291 PolarHBondContact OE1-OG 3.01Å; L289-S291 WeakPolarHBondContact CD2-OG 3.36Å; L289-S291 VanDerWaalsContact CG-OG 3.32Å; L289-S291 WeakPolarHBondContact CG-OG 3.35Å; L289-S291 PolarHBondContact O-N 3.36Å; S291-Q293 VanDerWaalsContact C-N 3.34Å; S291-V294 PolarHBondContact O-N 2.85Å; S291-L295 WeakPolarHBondContact O-CB 3.48Å; S291-L295 PolarHBondContact O-N 3.14Å
292	V	78.4	Confident	75.3	Confident	5 Å²	5	48.3 Å²	48.3	3%	0.03	28%	0.282	C	S	.	.	H	α-helix	trans	-67.7	-37.7	171.4	167.7	0	0	0	0	110.5	F228 I285 L286 L289 V294 L295 L296	F228-V292 HydrophobicContact CB-CG2 3.68Å; F228-V292 HydrophobicContact CD1-CG2 4.02Å; F228-V292 HydrophobicContact CD2-CG1 4.1Å; F228-V292 HydrophobicContact CD2-CG2 3.73Å; F228-V292 HydrophobicContact CE2-CG1 3.97Å; F228-V292 HydrophobicContact CE2-CG2 4.35Å; F228-V292 HydrophobicContact CG-CG2 3.52Å; F228-V292 HydrophobicContact CZ-CG1 4.34Å; I285-V292 HydrophobicContact CG2-CG2 4.03Å; L286-V292 HydrophobicContact CD2-CG1 3.52Å; L289-V292 HydrophobicContact CB-CB 4.36Å; L289-V292 HydrophobicContact CD2-CB 4.25Å; L289-V292 HydrophobicContact CD2-CG2 3.63Å; L289-V292 PolarHBondContact O-N 3.29Å; V292-V294 VanDerWaalsContact C-N 3.35Å; V292-V294 PolarHBondContact O-N 2.72Å; V292-L295 PolarHBondContact O-N 2.84Å; V292-L296 HydrophobicContact CG1-CD1 3.6Å; V292-L296 HydrophobicContact CG1-CG 4.07Å; V292-L296 VanDerWaalsContact O-CB 3.32Å; V292-L296 WeakPolarHBondContact O-CB 3.38Å; V292-L296 VanDerWaalsContact O-CG 3.26Å; V292-L296 WeakPolarHBondContact O-CG 3.49Å; V292-L296 PolarHBondContact O-N 3.39Å
293	Q	78.4	Confident	73.3	Confident	96 Å²	96	52.8 Å²	52.8	45%	0.449	31%	0.313	S	S	.	.	H	α-helix	trans	-59.8	-43.7	172.8	174.9	176.2	2.1	0	0	112.1	L289 P290 S291 L296 S297 Y401	L289-Q293 PolarHBondContact O-N 3.25Å; L289-Q293 VanDerWaalsContact O-N 3.16Å; P290-Q293 CarbonylContact O-C 3.43Å; P290-Q293 WeakPolarHBondContact O-CB 3.2Å; P290-Q293 PolarHBondContact O-N 2.83Å; S291-Q293 VanDerWaalsContact C-N 3.34Å; Q293-L296 PolarHBondContact O-N 3.44Å; Q293-S297 VanDerWaalsContact O-CB 3.22Å; Q293-S297 WeakPolarHBondContact O-CB 3.47Å; Q293-S297 PolarHBondContact O-N 2.97Å; Q293-S297 PolarHBondContact O-OG 3.24Å; Q293-Y401 HydrophobicContact CB-CD1 4.2Å; Q293-Y401 HydrophobicContact CB-CE1 3.78Å; Q293-Y401 HydrophobicContact CG-CD1 3.56Å; Q293-Y401 HydrophobicContact CG-CE1 3.66Å; Q293-Y401 HydrophobicContact CG-CG 4.06Å
294	V	75	Confident	71.4	Confident	79 Å²	79	59.3 Å²	59.3	48%	0.479	35%	0.348	S	S	.	.	H	α-helix	trans	-64.2	-46.5	175.5	172.7	0	0	0	0	110.8	Y216 P290 S291 V292 L296 S297 S298	Y216-V294 HydrophobicContact CE2-CG2 4.23Å; P290-V294 WeakPolarHBondContact O-CG2 3.45Å; P290-V294 PolarHBondContact O-N 2.96Å; S291-V294 PolarHBondContact O-N 2.85Å; V292-V294 VanDerWaalsContact C-N 3.35Å; V292-V294 PolarHBondContact O-N 2.72Å; V294-L296 VanDerWaalsContact C-N 3.31Å; V294-L296 PolarHBondContact O-N 3.48Å; V294-S297 WeakPolarHBondContact CA-OG 3.27Å; V294-S297 PolarHBondContact O-N 3.47Å; V294-S297 PolarHBondContact O-OG 3.33Å; V294-S298 PolarHBondContact O-N 3.06Å
295	L	75.9	Confident	70.3	Confident	41 Å²	41	61 Å²	61	22%	0.215	36%	0.357	C	S	.	.	H	α-helix	trans	-56	-47.1	177	-179.7	68.4	0	0	0	111.2	F228 S291 V292 S298	F228-L295 HydrophobicContact CD1-CD2 4.17Å; F228-L295 HydrophobicContact CE1-CD2 3.9Å; S291-L295 WeakPolarHBondContact O-CB 3.48Å; S291-L295 PolarHBondContact O-N 3.14Å; V292-L295 PolarHBondContact O-N 2.84Å; L295-S298 PolarHBondContact O-OG 3.23Å
296	L	78	Confident	69.1	Low	3 Å²	3	68.5 Å²	68.5	2%	0.016	39%	0.39	C	S	.	.	H	α-helix	trans	-82.4	-16	-175.5	-63.6	-179.5	0	0	0	114.2	L286 V292 Q293 V294 M312 F315 Y401 L402 Y405	L286-L296 HydrophobicContact CD2-CD1 3.38Å; V292-L296 HydrophobicContact CG1-CD1 3.6Å; V292-L296 HydrophobicContact CG1-CG 4.07Å; V292-L296 VanDerWaalsContact O-CB 3.32Å; V292-L296 WeakPolarHBondContact O-CB 3.38Å; V292-L296 VanDerWaalsContact O-CG 3.26Å; V292-L296 WeakPolarHBondContact O-CG 3.49Å; V292-L296 PolarHBondContact O-N 3.39Å; Q293-L296 PolarHBondContact O-N 3.44Å; V294-L296 VanDerWaalsContact C-N 3.31Å; V294-L296 PolarHBondContact O-N 3.48Å; L296-M312 HydrophobicContact CD2-CE 3.69Å; L296-M312 HydrophobicContact CD2-SD 3.37Å; L296-M312 WeakPolarHBondContact CD2-SD 3.37Å; L296-F315 HydrophobicContact CD1-CD1 4.4Å; L296-F315 HydrophobicContact CD1-CE1 3.65Å; L296-F315 HydrophobicContact CD1-CE2 4.37Å; L296-F315 HydrophobicContact CD1-CZ 3.62Å; L296-F315 HydrophobicContact CD2-CD1 3.6Å; L296-F315 HydrophobicContact CD2-CE1 3.52Å; L296-F315 HydrophobicContact CD2-CG 4.43Å; L296-F315 HydrophobicContact CD2-CZ 4.3Å; L296-F315 HydrophobicContact CG-CE1 4.23Å; L296-Y401 HydrophobicContact CB-CD2 4.19Å; L296-Y401 HydrophobicContact CB-CE2 4.13Å; L296-Y401 HydrophobicContact CD1-CE2 4.01Å; L296-L402 HydrophobicContact CD1-CD2 3.83Å; L296-Y405 HydrophobicContact CB-CE2 4.42Å; L296-Y405 PolarHBondContact O-OH 3.12Å
297	S	73.4	Confident	67.9	Low	66 Å²	66	73.8 Å²	73.8	46%	0.462	42%	0.417	S	S	.	.	H	α-helix	trans	-89.9	-18.9	173.2	55.3	0	0	0	0	113	Q293 V294 T299	Q293-S297 VanDerWaalsContact O-CB 3.22Å; Q293-S297 WeakPolarHBondContact O-CB 3.47Å; Q293-S297 PolarHBondContact O-N 2.97Å; Q293-S297 PolarHBondContact O-OG 3.24Å; V294-S297 WeakPolarHBondContact CA-OG 3.27Å; V294-S297 PolarHBondContact O-N 3.47Å; V294-S297 PolarHBondContact O-OG 3.33Å; S297-T299 PolarHBondContact O-N 2.9Å
298	S	66.9	Low	67.1	Low	49 Å²	49	76.8 Å²	76.8	34%	0.343	42%	0.423	S	S	.	.			trans	-70.9	100.4	174.3	66.8	0	0	0	0	110.9	V294 L295	V294-S298 PolarHBondContact O-N 3.06Å; L295-S298 PolarHBondContact O-OG 3.23Å
299	T	54.4	Low	66.4	Low	133 Å²	133	74.5 Å²	74.5	82%	0.816	42%	0.418	S	S	*	.			trans	-71.9	-23.1	170.9	48.5	0	0	0	0	111.9	S297 S301	S297-T299 PolarHBondContact O-N 2.9Å; T299-S301 PolarHBondContact O-N 3.22Å
300	T	50.5	Low	66.1	Low	118 Å²	118	79.5 Å²	79.5	72%	0.724	44%	0.441	S	S	*	.			trans	-97.8	78.8	-179.6	55.8	0	0	0	0	110.2	S302	T300-S302 PolarHBondContact O-N 2.94Å
301	S	51.2	Low	66.2	Low	78 Å²	78	80.5 Å²	80.5	55%	0.545	44%	0.444	S	S	.	.			trans	-68.2	117.4	159.2	53.2	0	0	0	0	107.3	T299 S303	T299-S301 PolarHBondContact O-N 3.22Å; S301-S303 PolarHBondContact O-N 2.9Å
302	S	51	Low	66.5	Low	86 Å²	86	81.7 Å²	81.7	60%	0.601	45%	0.449	S	S	*	.			trans	-55.5	129.5	161.1	52.6	0	0	0	0	107.1	T300 D304	T300-S302 PolarHBondContact O-N 2.94Å; S302-D304 PolarHBondContact O-N 3.31Å
303	S	51.3	Low	66.8	Low	94 Å²	94	86 Å²	86	66%	0.657	47%	0.472	S	S	*	.	T	Hydrogen-bonded Turn	trans	-51.4	-11.8	-173.9	50.3	0	0	0	0	116.3	S301	S301-S303 PolarHBondContact O-N 2.9Å
304	D	51.7	Low	67.2	Low	139 Å²	139	84.4 Å²	84.4	74%	0.743	46%	0.463	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88	-18.8	-166.3	-65.1	-8.4	0	0	0	113.8	S302 K306	S302-D304 PolarHBondContact O-N 3.31Å; D304-K306 PolarHBondContact O-N 3.43Å
305	D	63.7	Low	67.9	Low	58 Å²	58	80.7 Å²	80.7	31%	0.31	44%	0.441	S	S	.	.			trans	-95.4	73.2	-177.5	-151.2	-16.4	0	0	0	112.2	I307 R308 I309	D305-I307 PolarHBondContact O-N 3.23Å; D305-I307 VanDerWaalsContact O-N 3.09Å; D305-R308 HydrophobicContact CB-CB 4.15Å; D305-R308 HydrophobicContact CB-CG 4.17Å; D305-R308 PolarHBondContact O-N 2.9Å; D305-R308 VanDerWaalsContact O-N 3.09Å; D305-R308 WeakPolarHBondContact OD2-CD 3.48Å; D305-R308 WeakPolarHBondContact OD2-CG 3.32Å; D305-R308 IonicContact OD2-CZ 3.61Å; D305-R308 IonicContact OD2-NE 2.95Å; D305-R308 PolarHBondContact OD2-NE 2.9Å; D305-I309 PolarHBondContact O-N 3.39Å; D305-I309 VanDerWaalsContact O-N 3.16Å
306	K	64	Low	68.4	Low	162 Å²	162	80.2 Å²	80.2	70%	0.704	44%	0.438	S	S	*	.	H	α-helix	trans	-51.7	-32.4	-179.4	-72.4	-175.9	178.8	178.7	0	113.6	D304 Q310	D304-K306 PolarHBondContact O-N 3.43Å; K306-Q310 WeakPolarHBondContact O-CG 3.37Å; K306-Q310 PolarHBondContact O-N 3.43Å
307	I	64.8	Low	68.9	Low	112 Å²	112	80.8 Å²	80.8	57%	0.574	44%	0.443	S	S	*	.	H	α-helix	trans	-69.7	-47.7	-179.4	-62.4	173.8	0	0	0	109.6	D305 I309 Q310 E311	D305-I307 PolarHBondContact O-N 3.23Å; D305-I307 VanDerWaalsContact O-N 3.09Å; I307-I309 VanDerWaalsContact C-N 3.31Å; I307-I309 PolarHBondContact O-N 3.32Å; I307-Q310 PolarHBondContact O-N 3.03Å; I307-E311 WeakPolarHBondContact O-CG 3.25Å; I307-E311 PolarHBondContact O-N 3.24Å
308	R	68.3	Low	69.7	Low	145 Å²	145	77.7 Å²	77.7	55%	0.547	42%	0.422	S	S	.	.	H	α-helix	trans	-60.4	-40.1	177.3	-71.7	-174.5	-176.3	-174.2	-2.1	112.6	D305 E311 M312	D305-R308 HydrophobicContact CB-CB 4.15Å; D305-R308 HydrophobicContact CB-CG 4.17Å; D305-R308 PolarHBondContact O-N 2.9Å; D305-R308 VanDerWaalsContact O-N 3.09Å; D305-R308 WeakPolarHBondContact OD2-CD 3.48Å; D305-R308 WeakPolarHBondContact OD2-CG 3.32Å; D305-R308 IonicContact OD2-CZ 3.61Å; D305-R308 IonicContact OD2-NE 2.95Å; D305-R308 PolarHBondContact OD2-NE 2.9Å; R308-E311 PolarHBondContact O-N 3.14Å; R308-M312 WeakPolarHBondContact O-CB 3.4Å; R308-M312 PolarHBondContact O-N 2.84Å
309	I	67	Low	70.7	Confident	56 Å²	56	75.4 Å²	75.4	29%	0.287	41%	0.406	S	S	.	.	H	α-helix	trans	-61.6	-47.4	177.5	-63.1	169	0	0	0	110.2	D305 I307 E311 M312 D313	D305-I309 PolarHBondContact O-N 3.39Å; D305-I309 VanDerWaalsContact O-N 3.16Å; I307-I309 VanDerWaalsContact C-N 3.31Å; I307-I309 PolarHBondContact O-N 3.32Å; I309-E311 PolarHBondContact O-N 2.88Å; I309-M312 WeakPolarHBondContact O-CB 3.5Å; I309-M312 PolarHBondContact O-N 3.32Å; I309-D313 VanDerWaalsContact O-CG 3.3Å; I309-D313 PolarHBondContact O-N 2.87Å
310	Q	75.8	Confident	72.2	Confident	114 Å²	114	70.3 Å²	70.3	53%	0.533	37%	0.373	S	S	.	.	H	α-helix	trans	-64.8	-36.5	178.6	-72.9	-179.7	7.3	0	0	113.5	K306 I307 K314	K306-Q310 WeakPolarHBondContact O-CG 3.37Å; K306-Q310 PolarHBondContact O-N 3.43Å; I307-Q310 PolarHBondContact O-N 3.03Å; Q310-K314 VanDerWaalsContact O-CG 3.27Å; Q310-K314 WeakPolarHBondContact O-CG 3.41Å; Q310-K314 PolarHBondContact O-N 3.48Å
311	E	75.6	Confident	74.1	Confident	45 Å²	45	66.8 Å²	66.8	21%	0.21	35%	0.346	C	S	.	.	H	α-helix	trans	-66	-42.4	175.1	-72.1	-179.8	163.9	0	0	111.5	S229 I307 R308 I309 K314 F315	S229-E311 WeakPolarHBondContact CB-OE1 3.39Å; S229-E311 PolarHBondContact OG-OE1 3.28Å; S229-E311 PolarHBondContact OG-OE2 3.43Å; I307-E311 WeakPolarHBondContact O-CG 3.25Å; I307-E311 PolarHBondContact O-N 3.24Å; R308-E311 PolarHBondContact O-N 3.14Å; I309-E311 PolarHBondContact O-N 2.88Å; E311-K314 PolarHBondContact O-N 3.01Å; E311-F315 WeakPolarHBondContact O-CB 3.25Å; E311-F315 PolarHBondContact O-N 2.87Å
312	M	81.4	Confident	76	Confident	37 Å²	37	63.1 Å²	63.1	18%	0.182	32%	0.321	C	S	.	.	H	α-helix	trans	-61.9	-46.9	175.8	-172.9	61.8	124.2	0	0	111.4	L296 R308 I309 K314 F315 L316 Y405	L296-M312 HydrophobicContact CD2-CE 3.69Å; L296-M312 HydrophobicContact CD2-SD 3.37Å; L296-M312 WeakPolarHBondContact CD2-SD 3.37Å; R308-M312 WeakPolarHBondContact O-CB 3.4Å; R308-M312 PolarHBondContact O-N 2.84Å; I309-M312 WeakPolarHBondContact O-CB 3.5Å; I309-M312 PolarHBondContact O-N 3.32Å; M312-K314 VanDerWaalsContact C-N 3.33Å; M312-K314 PolarHBondContact O-N 3.44Å; M312-F315 WeakPolarHBondContact O-CB 3.37Å; M312-F315 PolarHBondContact O-N 2.81Å; M312-F315 HydrophobicContact SD-CD1 4.15Å; M312-L316 HydrophobicContact CG-CD1 4.05Å; M312-L316 HydrophobicContact CG-CG 4.3Å; M312-L316 WeakPolarHBondContact O-CB 3.47Å; M312-L316 VanDerWaalsContact O-CG 3.24Å; M312-L316 WeakPolarHBondContact O-CG 3.45Å; M312-L316 PolarHBondContact O-N 3.42Å; M312-L316 HydrophobicContact SD-CG 4.36Å; M312-Y405 VanDerWaalsContact CE-OH 3.31Å; M312-Y405 WeakPolarHBondContact CE-OH 3.31Å
313	D	83.8	Confident	77.9	Confident	95 Å²	95	59.2 Å²	59.2	51%	0.508	29%	0.293	S	S	.	.	H	α-helix	trans	-59.5	-42.9	178.9	-69.5	-23.2	0	0	0	112.2	I309 L316 A317	I309-D313 VanDerWaalsContact O-CG 3.3Å; I309-D313 PolarHBondContact O-N 2.87Å; D313-L316 PolarHBondContact O-N 3.24Å; D313-A317 WeakPolarHBondContact O-CB 3.11Å; D313-A317 PolarHBondContact O-N 3.28Å
314	K	87.7	Confident	79.8	Confident	63 Å²	63	54.9 Å²	54.9	27%	0.274	26%	0.262	S	S	.	.	H	α-helix	trans	-64.4	-43.1	176.3	-70.1	175.1	-173.8	164.2	0	111.8	V232 H236 Q310 E311 M312 A317 I318	V232-K314 HydrophobicContact CG1-CB 3.89Å; H236-K314 VanDerWaalsContact CD2-CG 3.47Å; H236-K314 WeakPolarHBondContact CD2-CG 3.4Å; Q310-K314 VanDerWaalsContact O-CG 3.27Å; Q310-K314 WeakPolarHBondContact O-CG 3.41Å; Q310-K314 PolarHBondContact O-N 3.48Å; E311-K314 PolarHBondContact O-N 3.01Å; M312-K314 VanDerWaalsContact C-N 3.33Å; M312-K314 PolarHBondContact O-N 3.44Å; K314-A317 PolarHBondContact O-N 3.43Å; K314-I318 WeakPolarHBondContact O-CG1 3.24Å; K314-I318 PolarHBondContact O-N 3.4Å
315	F	88.7	Confident	81.7	Confident	0 Å²	0	48.3 Å²	48.3	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-61.6	-47.5	176.4	169	-104.4	0	0	0	111.3	F228 V232 L286 L296 E311 M312 A317 I318 I319 L402	F228-F315 HydrophobicContact CE2-CD2 4.13Å; F228-F315 HydrophobicContact CE2-CE2 4.38Å; F228-F315 HydrophobicContact CZ-CB 4.34Å; F228-F315 AromaticContact CZ-CD2 3.87Å; F228-F315 HydrophobicContact CZ-CD2 3.87Å; F228-F315 HydrophobicContact CZ-CE2 4.4Å; F228-F315 HydrophobicContact CZ-CG 4.07Å; V232-F315 HydrophobicContact CG1-CB 4.24Å; V232-F315 HydrophobicContact CG2-CB 4.4Å; V232-F315 HydrophobicContact CG2-CD2 4.3Å; L286-F315 HydrophobicContact CD1-CE2 3.91Å; L286-F315 HydrophobicContact CD1-CZ 4.32Å; L286-F315 HydrophobicContact CD2-CE2 3.99Å; L286-F315 HydrophobicContact CD2-CZ 4Å; L296-F315 HydrophobicContact CD1-CD1 4.4Å; L296-F315 HydrophobicContact CD1-CE1 3.65Å; L296-F315 HydrophobicContact CD1-CE2 4.37Å; L296-F315 HydrophobicContact CD1-CZ 3.62Å; L296-F315 HydrophobicContact CD2-CD1 3.6Å; L296-F315 HydrophobicContact CD2-CE1 3.52Å; L296-F315 HydrophobicContact CD2-CG 4.43Å; L296-F315 HydrophobicContact CD2-CZ 4.3Å; L296-F315 HydrophobicContact CG-CE1 4.23Å; E311-F315 WeakPolarHBondContact O-CB 3.25Å; E311-F315 PolarHBondContact O-N 2.87Å; M312-F315 WeakPolarHBondContact O-CB 3.37Å; M312-F315 PolarHBondContact O-N 2.81Å; M312-F315 HydrophobicContact SD-CD1 4.15Å; F315-A317 VanDerWaalsContact C-N 3.33Å; F315-A317 PolarHBondContact O-N 3.07Å; F315-I318 WeakPolarHBondContact O-CB 3.35Å; F315-I318 PolarHBondContact O-N 3.11Å; F315-I318 VanDerWaalsContact O-N 3.15Å; F315-I319 HydrophobicContact CD1-CG1 4.49Å; F315-I319 HydrophobicContact CD2-CG1 4.07Å; F315-I319 HydrophobicContact CE1-CG1 3.98Å; F315-I319 HydrophobicContact CE2-CD1 3.82Å; F315-I319 HydrophobicContact CE2-CG1 3.51Å; F315-I319 HydrophobicContact CZ-CD1 4.03Å; F315-I319 HydrophobicContact CZ-CG1 3.47Å; F315-I319 VanDerWaalsContact CZ-CG1 3.47Å; F315-I319 WeakPolarHBondContact O-CG1 3.42Å; F315-I319 PolarHBondContact O-N 3.25Å; F315-L402 HydrophobicContact CE1-CD2 4.2Å; F315-L402 HydrophobicContact CZ-CD2 3.81Å
316	L	87.9	Confident	83.1	Confident	31 Å²	31	45.7 Å²	45.7	16%	0.162	21%	0.213	C	C	.	.	H	α-helix	trans	-59.4	-42.9	178.6	-70.6	176.2	0	0	0	111.9	M312 D313 I318 I319 Q320 Y405	M312-L316 HydrophobicContact CG-CD1 4.05Å; M312-L316 HydrophobicContact CG-CG 4.3Å; M312-L316 WeakPolarHBondContact O-CB 3.47Å; M312-L316 VanDerWaalsContact O-CG 3.24Å; M312-L316 WeakPolarHBondContact O-CG 3.45Å; M312-L316 PolarHBondContact O-N 3.42Å; M312-L316 HydrophobicContact SD-CG 4.36Å; D313-L316 PolarHBondContact O-N 3.24Å; L316-I318 VanDerWaalsContact C-N 3.3Å; L316-I318 PolarHBondContact O-N 3.05Å; L316-I319 PolarHBondContact O-N 3.06Å; L316-Q320 VanDerWaalsContact O-CB 3.26Å; L316-Q320 WeakPolarHBondContact O-CB 3.31Å; L316-Q320 WeakPolarHBondContact O-CG 3.16Å; L316-Q320 PolarHBondContact O-N 3.4Å; L316-Y405 HydrophobicContact CD2-CD1 3.17Å; L316-Y405 HydrophobicContact CD2-CE1 3.41Å; L316-Y405 VanDerWaalsContact CD2-CE1 3.41Å; L316-Y405 HydrophobicContact CD2-CG 3.8Å
317	A	88.8	Confident	84.4	Confident	15 Å²	15	38 Å²	38	12%	0.124	18%	0.18	C	C	.	.	H	α-helix	trans	-58.9	-40.1	176.6	0	0	0	0	0	112.8	L244 D313 K314 F315 Y321 G322	L244-A317 HydrophobicContact CB-CB 4.17Å; L244-A317 HydrophobicContact CD2-CB 4.42Å; L244-A317 WeakPolarHBondContact O-CB 3.07Å; D313-A317 WeakPolarHBondContact O-CB 3.11Å; D313-A317 PolarHBondContact O-N 3.28Å; K314-A317 PolarHBondContact O-N 3.43Å; F315-A317 VanDerWaalsContact C-N 3.33Å; F315-A317 PolarHBondContact O-N 3.07Å; A317-Y321 PolarHBondContact O-N 3.36Å; A317-G322 PolarHBondContact O-N 2.91Å; A317-G322 VanDerWaalsContact O-N 3.11Å
318	I	89.6	Confident	85.6	Confident	1 Å²	1	32.6 Å²	32.6	1%	0.005	15%	0.152	C	C	.	.	I	π-helix	trans	-66.2	-46.9	176.8	-64.9	163.2	0	0	0	110.8	V232 L235 H236 L244 K314 F315 L316 G322 F323	V232-I318 HydrophobicContact CG1-CD1 4.16Å; L235-I318 HydrophobicContact CB-CD1 3.77Å; H236-I318 HydrophobicContact CB-CD1 4.37Å; L244-I318 HydrophobicContact CD2-CG1 3.8Å; K314-I318 WeakPolarHBondContact O-CG1 3.24Å; K314-I318 PolarHBondContact O-N 3.4Å; F315-I318 WeakPolarHBondContact O-CB 3.35Å; F315-I318 PolarHBondContact O-N 3.11Å; F315-I318 VanDerWaalsContact O-N 3.15Å; L316-I318 VanDerWaalsContact C-N 3.3Å; L316-I318 PolarHBondContact O-N 3.05Å; I318-G322 VanDerWaalsContact O-CA 3.25Å; I318-G322 WeakPolarHBondContact O-CA 3.36Å; I318-G322 PolarHBondContact O-N 3.41Å; I318-G322 VanDerWaalsContact O-N 3.07Å; I318-F323 PolarHBondContact O-N 2.82Å
319	I	87.3	Confident	86.6	Confident	2 Å²	2	25.7 Å²	25.7	1%	0.01	13%	0.126	C	C	.	.	I	π-helix	trans	-70.1	-44.1	-176.9	-63.9	-58.3	0	0	0	111.9	F315 L316 F323 L396 F406	F315-I319 HydrophobicContact CD1-CG1 4.49Å; F315-I319 HydrophobicContact CD2-CG1 4.07Å; F315-I319 HydrophobicContact CE1-CG1 3.98Å; F315-I319 HydrophobicContact CE2-CD1 3.82Å; F315-I319 HydrophobicContact CE2-CG1 3.51Å; F315-I319 HydrophobicContact CZ-CD1 4.03Å; F315-I319 HydrophobicContact CZ-CG1 3.47Å; F315-I319 VanDerWaalsContact CZ-CG1 3.47Å; F315-I319 WeakPolarHBondContact O-CG1 3.42Å; F315-I319 PolarHBondContact O-N 3.25Å; L316-I319 PolarHBondContact O-N 3.06Å; I319-F323 HydrophobicContact CD1-CE2 4.07Å; I319-L396 HydrophobicContact CD1-CD1 4.11Å; I319-F406 HydrophobicContact CG2-CD1 4.39Å; I319-F406 HydrophobicContact CG2-CE1 3.85Å; I319-F406 HydrophobicContact CG2-CE2 4.15Å; I319-F406 HydrophobicContact CG2-CZ 3.72Å
320	Q	86.3	Confident	87.7	Confident	26 Å²	26	23 Å²	23	12%	0.121	11%	0.112	C	C	.	.	I	π-helix	trans	-77.8	-45	-174.6	-70	177.4	-16.2	0	0	112.2	L316 T409	L316-Q320 VanDerWaalsContact O-CB 3.26Å; L316-Q320 WeakPolarHBondContact O-CB 3.31Å; L316-Q320 WeakPolarHBondContact O-CG 3.16Å; L316-Q320 PolarHBondContact O-N 3.4Å; Q320-T409 HydrophobicContact CB-CG2 3.93Å; Q320-T409 HydrophobicContact CG-CG2 4.34Å
321	Y	90.2	Very high	88.2	Confident	44 Å²	44	17.6 Å²	17.6	17%	0.173	9%	0.087	C	C	.	.	I	π-helix	trans	-113.5	-36	-171.1	-52.1	-61.4	0	0	0	113.2	F243 E246 A317 F323 M324 N325 T409	F243-Y321 CarbonylContact O-C 3.5Å; E246-Y321 HydrophobicContact CB-CD1 4.16Å; E246-Y321 HydrophobicContact CB-CE1 3.56Å; E246-Y321 HydrophobicContact CG-CE1 4Å; A317-Y321 PolarHBondContact O-N 3.36Å; Y321-F323 PolarHBondContact O-N 3.15Å; Y321-M324 HydrophobicContact CD1-CE 4.13Å; Y321-M324 PolarHBondContact O-N 3.43Å; Y321-N325 WeakPolarHBondContact O-CB 3.22Å; Y321-N325 PolarHBondContact O-N 2.98Å; Y321-N325 PolarHBondContact O-ND2 2.96Å; Y321-T409 HydrophobicContact CE1-CG2 4.39Å
322	G	91.1	Very high	88.6	Confident	1 Å²	1	16.6 Å²	16.6	1%	0.01	8%	0.082	C	C	.	.	I	π-helix	trans	-55.3	-54.2	-175.5	0	0	0	0	0	113.5	F243 A317 I318 M324 N325 L326	F243-G322 WeakPolarHBondContact O-CA 3.36Å; F243-G322 PolarHBondContact O-N 2.89Å; A317-G322 PolarHBondContact O-N 2.91Å; A317-G322 VanDerWaalsContact O-N 3.11Å; I318-G322 VanDerWaalsContact O-CA 3.25Å; I318-G322 WeakPolarHBondContact O-CA 3.36Å; I318-G322 PolarHBondContact O-N 3.41Å; I318-G322 VanDerWaalsContact O-N 3.07Å; G322-M324 PolarHBondContact O-N 2.97Å; G322-N325 PolarHBondContact O-N 3.44Å; G322-L326 WeakPolarHBondContact O-CB 3.38Å; G322-L326 VanDerWaalsContact O-CG 3.27Å; G322-L326 WeakPolarHBondContact O-CG 3.49Å; G322-L326 PolarHBondContact O-N 2.98Å
323	F	90.7	Very high	88.7	Confident	4 Å²	4	17.1 Å²	17.1	2%	0.018	9%	0.087	C	C	.	.	H	α-helix	trans	-62.3	-44.4	179.4	-78.5	-83.2	0	0	0	112.9	L279 I318 I319 Y321 L326 C327 L389 L393 L396	L279-F323 HydrophobicContact CD2-CE1 4.37Å; L279-F323 HydrophobicContact CD2-CE2 4.46Å; L279-F323 HydrophobicContact CD2-CZ 3.84Å; I318-F323 PolarHBondContact O-N 2.82Å; I319-F323 HydrophobicContact CD1-CE2 4.07Å; Y321-F323 PolarHBondContact O-N 3.15Å; F323-L326 PolarHBondContact O-N 3.38Å; F323-C327 PolarHBondContact O-N 3.28Å; F323-C327 PolarHBondContact O-SG 2.97Å; F323-C327 VanDerWaalsContact O-SG 3.34Å; F323-L389 HydrophobicContact CD1-CD1 3.56Å; F323-L389 HydrophobicContact CD1-CG 4.3Å; F323-L389 HydrophobicContact CE1-CD1 3.61Å; F323-L393 HydrophobicContact CB-CD1 4.21Å; F323-L393 HydrophobicContact CD1-CB 3.97Å; F323-L393 HydrophobicContact CD1-CD1 3.97Å; F323-L393 HydrophobicContact CD1-CD2 4.42Å; F323-L393 HydrophobicContact CD1-CG 4.34Å; F323-L393 HydrophobicContact CD2-CD1 4.38Å; F323-L393 HydrophobicContact CE1-CB 4.05Å; F323-L393 HydrophobicContact CE1-CD1 4.44Å; F323-L393 HydrophobicContact CG-CD1 3.93Å; F323-L396 HydrophobicContact CE1-CD1 4.37Å; F323-L396 HydrophobicContact CE2-CD1 3.62Å; F323-L396 HydrophobicContact CZ-CD1 3.4Å; F323-L396 VanDerWaalsContact CZ-CD1 3.4Å
324	M	90.5	Very high	88.4	Confident	3 Å²	3	13.6 Å²	13.6	2%	0.015	7%	0.067	C	C	.	.	H	α-helix	trans	-60.6	-49.5	179.9	-175.5	-177.1	69.5	0	0	111.2	F250 Y321 G322 L326 C327 L328 N412 C416	F250-M324 HydrophobicContact CD2-CE 3.92Å; F250-M324 HydrophobicContact CD2-SD 4.3Å; F250-M324 HydrophobicContact CE2-CE 3.57Å; F250-M324 HydrophobicContact CE2-CG 4.02Å; F250-M324 HydrophobicContact CE2-SD 3.42Å; F250-M324 WeakPolarHBondContact CE2-SD 3.31Å; F250-M324 HydrophobicContact CZ-SD 3.92Å; Y321-M324 HydrophobicContact CD1-CE 4.13Å; Y321-M324 PolarHBondContact O-N 3.43Å; G322-M324 PolarHBondContact O-N 2.97Å; M324-L326 VanDerWaalsContact C-N 3.33Å; M324-L326 PolarHBondContact O-N 3Å; M324-C327 WeakPolarHBondContact O-CB 3.04Å; M324-C327 PolarHBondContact O-N 3.23Å; M324-C327 VanDerWaalsContact O-N 3.16Å; M324-L328 WeakPolarHBondContact O-CG 3.32Å; M324-L328 PolarHBondContact O-N 3.47Å; M324-N412 HydrophobicContact SD-CB 3.49Å; M324-N412 WeakPolarHBondContact SD-CB 3.4Å; M324-C416 HydrophobicContact CG-CB 4.04Å; M324-C416 WeakPolarHBondContact CG-SG 3.24Å
325	N	92.2	Very high	87.8	Confident	1 Å²	1	11.4 Å²	11.4	1%	0.005	6%	0.058	C	C	.	.	H	α-helix	trans	-67.4	-33	179.5	-71.2	-31.3	0	0	0	112.2	V242 F243 L259 Y321 G322 L328 A329	V242-N325 PolarHBondContact O-ND2 3.41Å; F243-N325 HydrophobicContact CB-CB 4.26Å; F243-N325 HydrophobicContact CD1-CB 3.64Å; F243-N325 HydrophobicContact CE1-CB 4.3Å; F243-N325 HydrophobicContact CG-CB 4.18Å; F243-N325 PolarHBondContact O-ND2 3.2Å; L259-N325 HydrophobicContact CD1-CB 4.24Å; L259-N325 HydrophobicContact CD2-CB 4.28Å; Y321-N325 WeakPolarHBondContact O-CB 3.22Å; Y321-N325 PolarHBondContact O-N 2.98Å; Y321-N325 PolarHBondContact O-ND2 2.96Å; G322-N325 PolarHBondContact O-N 3.44Å; N325-L328 PolarHBondContact O-N 2.95Å; N325-A329 VanDerWaalsContact O-CB 3.28Å; N325-A329 WeakPolarHBondContact O-CB 2.93Å; N325-A329 PolarHBondContact O-N 2.82Å
326	L	92.6	Very high	86.9	Confident	2 Å²	2	13 Å²	13	1%	0.01	7%	0.069	C	C	.	.	H	α-helix	trans	-62.2	-46.1	169.4	-75.8	167.4	0	0	0	111.6	L239 F243 L270 L275 G322 F323 M324 L328 A329 I330 F385 L389	L239-L326 HydrophobicContact CD2-CD1 4.24Å; L239-L326 HydrophobicContact CD2-CD2 4.15Å; L239-L326 HydrophobicContact CD2-CG 4.36Å; F243-L326 HydrophobicContact CD1-CD2 4.09Å; F243-L326 HydrophobicContact CD1-CG 4.03Å; F243-L326 HydrophobicContact CE1-CD2 3.82Å; F243-L326 HydrophobicContact CE1-CG 4.15Å; L270-L326 HydrophobicContact CD1-CD2 4.17Å; L275-L326 HydrophobicContact CD2-CD1 4.27Å; L275-L326 HydrophobicContact CD2-CD2 4.03Å; G322-L326 WeakPolarHBondContact O-CB 3.38Å; G322-L326 VanDerWaalsContact O-CG 3.27Å; G322-L326 WeakPolarHBondContact O-CG 3.49Å; G322-L326 PolarHBondContact O-N 2.98Å; F323-L326 PolarHBondContact O-N 3.38Å; M324-L326 VanDerWaalsContact C-N 3.33Å; M324-L326 PolarHBondContact O-N 3Å; L326-L328 VanDerWaalsContact C-N 3.32Å; L326-L328 PolarHBondContact O-N 3.25Å; L326-A329 PolarHBondContact O-N 2.7Å; L326-I330 WeakPolarHBondContact O-CB 3.47Å; L326-I330 WeakPolarHBondContact O-CD1 3.12Å; L326-I330 WeakPolarHBondContact O-CG1 3.36Å; L326-I330 PolarHBondContact O-N 3.31Å; L326-F385 HydrophobicContact CD2-CE1 4.48Å; L326-F385 HydrophobicContact CD2-CZ 4.43Å; L326-L389 HydrophobicContact CB-CD2 3.88Å; L326-L389 HydrophobicContact CD1-CD1 3.83Å; L326-L389 HydrophobicContact CD1-CD2 4.5Å
327	C	91.9	Very high	86	Confident	0 Å²	0	16.6 Å²	16.6	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-58.9	-42.7	175.8	-68.7	0	0	0	0	112.2	F323 M324 G331 C416 L420	F323-C327 PolarHBondContact O-N 3.28Å; F323-C327 PolarHBondContact O-SG 2.97Å; F323-C327 VanDerWaalsContact O-SG 3.34Å; M324-C327 WeakPolarHBondContact O-CB 3.04Å; M324-C327 PolarHBondContact O-N 3.23Å; M324-C327 VanDerWaalsContact O-N 3.16Å; C327-G331 PolarHBondContact O-N 3.27Å; C327-C416 HydrophobicContact CB-CB 4.11Å; C327-L420 HydrophobicContact CB-CD2 4.13Å
328	L	91	Very high	85	Confident	0 Å²	0	19.2 Å²	19.2	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-63.9	-47.1	176.3	-70.7	-179.6	0	0	0	112.6	F250 L256 L259 M324 N325 L326 G331 K332 L348 C416 Y419	F250-L328 HydrophobicContact CD2-CD1 4.2Å; F250-L328 HydrophobicContact CE2-CD1 3.73Å; F250-L328 HydrophobicContact CZ-CD1 4.49Å; L256-L328 HydrophobicContact CD2-CB 3.81Å; L256-L328 HydrophobicContact CD2-CD2 3.94Å; L256-L328 HydrophobicContact CD2-CG 4.31Å; L259-L328 HydrophobicContact CD1-CB 4.02Å; L259-L328 HydrophobicContact CD1-CD1 4.33Å; M324-L328 WeakPolarHBondContact O-CG 3.32Å; M324-L328 PolarHBondContact O-N 3.47Å; N325-L328 PolarHBondContact O-N 2.95Å; L326-L328 VanDerWaalsContact C-N 3.32Å; L326-L328 PolarHBondContact O-N 3.25Å; L328-G331 PolarHBondContact O-N 2.99Å; L328-K332 PolarHBondContact O-N 2.96Å; L328-L348 HydrophobicContact CD2-CD2 3.8Å; L328-C416 HydrophobicContact CD2-CB 4.16Å; L328-C416 WeakPolarHBondContact CD2-SG 3.32Å; L328-C416 HydrophobicContact CG-CB 4.32Å; L328-C416 WeakPolarHBondContact CG-SG 2.82Å; L328-Y419 HydrophobicContact CD2-CD1 3.92Å; L328-Y419 HydrophobicContact CD2-CE1 4.24Å
329	A	89.5	Confident	84.2	Confident	0 Å²	0	20 Å²	20	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-58	-51.3	179	0	0	0	0	0	110.9	F243 L259 I263 N325 L326 G331 K332 V333	F243-A329 HydrophobicContact CE1-CB 3.83Å; F243-A329 HydrophobicContact CZ-CB 3.88Å; L259-A329 HydrophobicContact CB-CB 3.86Å; I263-A329 HydrophobicContact CD1-CB 3.47Å; I263-A329 VanDerWaalsContact CD1-CB 3.47Å; I263-A329 HydrophobicContact CG1-CB 4.31Å; N325-A329 VanDerWaalsContact O-CB 3.28Å; N325-A329 WeakPolarHBondContact O-CB 2.93Å; N325-A329 PolarHBondContact O-N 2.82Å; L326-A329 PolarHBondContact O-N 2.7Å; A329-G331 PolarHBondContact O-N 3.45Å; A329-K332 PolarHBondContact O-N 3.28Å; A329-V333 WeakPolarHBondContact O-CG2 3.33Å; A329-V333 PolarHBondContact O-N 3.25Å
330	I	89.2	Confident	83.5	Confident	0 Å²	0	20.7 Å²	20.7	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-61.4	-46.6	179.5	-63.8	163.6	0	0	0	110.5	I263 L326 K332 V333 W334 L382 F385 T386 L389 L420	I263-I330 HydrophobicContact CD1-CG1 3.83Å; L326-I330 WeakPolarHBondContact O-CB 3.47Å; L326-I330 WeakPolarHBondContact O-CD1 3.12Å; L326-I330 WeakPolarHBondContact O-CG1 3.36Å; L326-I330 PolarHBondContact O-N 3.31Å; I330-K332 VanDerWaalsContact C-N 3.28Å; I330-K332 PolarHBondContact O-N 2.84Å; I330-V333 WeakPolarHBondContact O-CB 3.16Å; I330-V333 PolarHBondContact O-N 2.71Å; I330-V333 VanDerWaalsContact O-N 3.11Å; I330-W334 HydrophobicContact CG2-CD2 4.15Å; I330-W334 HydrophobicContact CG2-CE3 3.59Å; I330-W334 HydrophobicContact CG2-CH2 3.45Å; I330-W334 VanDerWaalsContact CG2-CH2 3.45Å; I330-W334 HydrophobicContact CG2-CZ2 3.99Å; I330-W334 HydrophobicContact CG2-CZ3 3.2Å; I330-W334 PolarHBondContact O-N 2.98Å; I330-L382 HydrophobicContact CG1-CD1 4.21Å; I330-L382 HydrophobicContact CG2-CD1 4.48Å; I330-F385 HydrophobicContact CD1-CD1 4.09Å; I330-F385 HydrophobicContact CD1-CE1 3.88Å; I330-T386 HydrophobicContact CD1-CG2 4.46Å; I330-T386 HydrophobicContact CG2-CG2 4.3Å; I330-T386 WeakPolarHBondContact CG2-OG1 3.13Å; I330-L389 HydrophobicContact CD1-CD2 3.67Å; I330-L420 HydrophobicContact CB-CD1 4.03Å; I330-L420 HydrophobicContact CG2-CD1 3.67Å
331	G	86.2	Confident	82.8	Confident	0 Å²	0	24.5 Å²	24.5	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-58.2	-41.2	178.7	0	0	0	0	0	112	C327 L328 A329 V333 W334 L335 C423	C327-G331 PolarHBondContact O-N 3.27Å; L328-G331 PolarHBondContact O-N 2.99Å; A329-G331 PolarHBondContact O-N 3.45Å; G331-V333 VanDerWaalsContact C-N 3.32Å; G331-V333 PolarHBondContact O-N 3.11Å; G331-W334 PolarHBondContact O-N 3.3Å; G331-W334 VanDerWaalsContact O-N 3.09Å; G331-L335 PolarHBondContact O-N 3.34Å; G331-C423 PolarHBondContact O-SG 3.26Å; G331-C423 VanDerWaalsContact O-SG 3.38Å
332	K	84.5	Confident	81.9	Confident	24 Å²	24	23.4 Å²	23.4	10%	0.104	15%	0.146	C	C	.	.	H	α-helix	trans	-63.7	-34.4	177.3	173.4	80.1	-144.3	74.1	0	113	Y253 L256 S260 L328 A329 I330 W334 L335 Y419	Y253-K332 HydrophobicContact CE2-CD 4.23Å; L256-K332 HydrophobicContact CB-CB 4.07Å; L256-K332 HydrophobicContact CB-CD 3.64Å; L256-K332 HydrophobicContact CB-CG 4.02Å; L256-K332 WeakPolarHBondContact O-CG 3.49Å; S260-K332 VanDerWaalsContact CB-CG 3.45Å; S260-K332 WeakPolarHBondContact OG-CG 3.43Å; L328-K332 PolarHBondContact O-N 2.96Å; A329-K332 PolarHBondContact O-N 3.28Å; I330-K332 VanDerWaalsContact C-N 3.28Å; I330-K332 PolarHBondContact O-N 2.84Å; K332-W334 PolarHBondContact O-N 3.35Å; K332-L335 HydrophobicContact CB-CD1 4.48Å; K332-L335 HydrophobicContact CD-CD1 3.79Å; K332-L335 PolarHBondContact O-N 3.48Å; K332-Y419 VanDerWaalsContact CA-OH 3.24Å; K332-Y419 WeakPolarHBondContact CA-OH 3.46Å; K332-Y419 PolarHBondContact N-OH 2.84Å
333	V	82.2	Confident	81.2	Confident	47 Å²	47	23.4 Å²	23.4	29%	0.285	15%	0.146	S	C	.	.	H	α-helix	trans	-63.1	-35.2	175	176.5	0	0	0	0	110.9	I263 T264 A329 I330 G331 L382	I263-V333 HydrophobicContact CB-CG2 3.96Å; I263-V333 HydrophobicContact CD1-CG2 4.27Å; I263-V333 HydrophobicContact CG2-CG2 3.89Å; T264-V333 HydrophobicContact CG2-CG1 4.26Å; T264-V333 HydrophobicContact CG2-CG2 3.83Å; A329-V333 WeakPolarHBondContact O-CG2 3.33Å; A329-V333 PolarHBondContact O-N 3.25Å; I330-V333 WeakPolarHBondContact O-CB 3.16Å; I330-V333 PolarHBondContact O-N 2.71Å; I330-V333 VanDerWaalsContact O-N 3.11Å; G331-V333 VanDerWaalsContact C-N 3.32Å; G331-V333 PolarHBondContact O-N 3.11Å; V333-L382 HydrophobicContact CB-CD2 4.08Å; V333-L382 HydrophobicContact CG1-CD2 3.6Å
334	W	78.1	Confident	80.3	Confident	21 Å²	21	26.3 Å²	26.3	8%	0.08	16%	0.164	C	C	.	.	H	α-helix	trans	-89.5	-13.2	-179.5	-67.3	-34.1	0	0	0	115.1	I330 G331 K332 C336 L382 L383 T386 L420 C423 L424 C427	I330-W334 HydrophobicContact CG2-CD2 4.15Å; I330-W334 HydrophobicContact CG2-CE3 3.59Å; I330-W334 HydrophobicContact CG2-CH2 3.45Å; I330-W334 VanDerWaalsContact CG2-CH2 3.45Å; I330-W334 HydrophobicContact CG2-CZ2 3.99Å; I330-W334 HydrophobicContact CG2-CZ3 3.2Å; I330-W334 PolarHBondContact O-N 2.98Å; G331-W334 PolarHBondContact O-N 3.3Å; G331-W334 VanDerWaalsContact O-N 3.09Å; K332-W334 PolarHBondContact O-N 3.35Å; W334-C336 PolarHBondContact O-N 3.37Å; W334-L382 HydrophobicContact CZ2-CD2 4.11Å; W334-L382 HydrophobicContact CZ2-CG 3.89Å; W334-L383 HydrophobicContact CH2-CD1 4.14Å; W334-L383 HydrophobicContact CZ2-CB 4.3Å; W334-L383 HydrophobicContact CZ2-CD1 4.31Å; W334-T386 HydrophobicContact CH2-CG2 3.81Å; W334-T386 WeakPolarHBondContact CH2-OG1 3.48Å; W334-T386 HydrophobicContact CZ3-CG2 4.01Å; W334-L420 HydrophobicContact CE3-CD1 3.95Å; W334-L420 HydrophobicContact CZ3-CD1 3.66Å; W334-C423 HydrophobicContact CB-CB 4.24Å; W334-L424 HydrophobicContact CD2-CD2 4.16Å; W334-L424 HydrophobicContact CE3-CD2 3.46Å; W334-L424 VanDerWaalsContact CE3-CD2 3.46Å; W334-L424 HydrophobicContact CE3-CG 3.63Å; W334-L424 HydrophobicContact CH2-CD2 3.46Å; W334-L424 VanDerWaalsContact CH2-CD2 3.46Å; W334-L424 HydrophobicContact CH2-CG 4.19Å; W334-L424 HydrophobicContact CZ2-CD2 4.17Å; W334-L424 HydrophobicContact CZ3-CD1 3.9Å; W334-L424 HydrophobicContact CZ3-CD2 3.06Å; W334-L424 HydrophobicContact CZ3-CG 3.33Å; W334-C427 WeakPolarHBondContact O-CB 3.27Å
335	L	74.8	Confident	79.3	Confident	17 Å²	17	32.5 Å²	32.5	9%	0.089	20%	0.197	C	C	.	.			trans	-52.2	128.4	177.7	-79.8	173.3	0	0	0	112.3	G331 K332 C339 L343 F351 Y419 C423	G331-L335 PolarHBondContact O-N 3.34Å; K332-L335 HydrophobicContact CB-CD1 4.48Å; K332-L335 HydrophobicContact CD-CD1 3.79Å; K332-L335 PolarHBondContact O-N 3.48Å; L335-C339 HydrophobicContact CD2-CB 3.63Å; L335-L343 HydrophobicContact CD1-CD1 3.52Å; L335-L343 HydrophobicContact CD2-CD1 3.55Å; L335-L343 HydrophobicContact CG-CD1 4.19Å; L335-F351 HydrophobicContact CD2-CZ 4.18Å; L335-Y419 HydrophobicContact CD1-CE2 4.45Å; L335-Y419 VanDerWaalsContact CD1-OH 3.25Å; L335-Y419 WeakPolarHBondContact CD1-OH 3.19Å; L335-Y419 HydrophobicContact CD2-CE2 4.09Å; L335-Y419 HydrophobicContact CG-CE2 4.42Å; L335-C423 VanDerWaalsContact CD2-SG 3.54Å
336	C	70.8	Confident	78.4	Confident	34 Å²	34	36.3 Å²	36.3	23%	0.23	22%	0.215	C	C	.	.			trans	-74.5	163.2	171.5	76.7	0	0	0	0	110.6	W334 A338 C339 S340 C427	W334-C336 PolarHBondContact O-N 3.37Å; C336-A338 PolarHBondContact O-N 3.21Å; C336-C339 PolarHBondContact O-N 3.45Å; C336-C339 PolarHBondContact SG-N 3.45Å; C336-C339 VanDerWaalsContact SG-N 3.36Å; C336-S340 WeakPolarHBondContact O-CB 3.5Å; C336-S340 PolarHBondContact O-N 3.38Å; C336-C427 HydrophobicContact CB-CB 3.88Å; C336-C427 PolarHBondContact N-SG 3.11Å
337	P	68.1	Low	77.4	Confident	106 Å²	106	38 Å²	38	69%	0.688	23%	0.226	S	C	*	.	H	α-helix	trans	-56.2	-36.4	178.4	-26.5	35.2	0	0	0	113.7	S340 N341	P337-S340 PolarHBondContact O-N 2.87Å; P337-N341 VanDerWaalsContact O-CG 3.24Å; P337-N341 PolarHBondContact O-N 3.31Å; P337-N341 PolarHBondContact O-ND2 3.14Å; P337-N341 PolarHBondContact O-OD1 2.62Å
338	A	67.6	Low	76.6	Confident	70 Å²	70	38 Å²	38	58%	0.579	23%	0.226	S	C	*	.	H	α-helix	trans	-65.4	-49.8	178.6	0	0	0	0	0	111.9	C336 S340 N341 S342	C336-A338 PolarHBondContact O-N 3.21Å; A338-S340 VanDerWaalsContact C-N 3.29Å; A338-S340 PolarHBondContact O-N 3.19Å; A338-N341 PolarHBondContact O-N 2.98Å; A338-S342 PolarHBondContact O-N 3.16Å
339	C	73	Confident	75.4	Confident	18 Å²	18	40.8 Å²	40.8	12%	0.122	24%	0.239	C	C	.	.	H	α-helix	trans	-67	-31.4	175.5	-63.3	0	0	0	0	112.4	L335 C336 N341 S342 L343 F351 C427	L335-C339 HydrophobicContact CD2-CB 3.63Å; C336-C339 PolarHBondContact O-N 3.45Å; C336-C339 PolarHBondContact SG-N 3.45Å; C336-C339 VanDerWaalsContact SG-N 3.36Å; C339-N341 VanDerWaalsContact C-N 3.31Å; C339-N341 PolarHBondContact O-N 2.96Å; C339-S342 WeakPolarHBondContact CA-OG 3.39Å; C339-S342 PolarHBondContact O-N 3.38Å; C339-S342 PolarHBondContact O-OG 2.52Å; C339-L343 WeakPolarHBondContact O-CD1 3.32Å; C339-L343 PolarHBondContact O-N 3.16Å; C339-L343 VanDerWaalsContact O-N 3.09Å; C339-F351 HydrophobicContact CB-CE2 3.72Å; C339-F351 HydrophobicContact CB-CZ 3.86Å; C339-C427 VanDerWaalsContact SG-SG 3.67Å
340	S	73.1	Confident	74.5	Confident	16 Å²	16	44 Å²	44	11%	0.112	26%	0.256	C	S	.	.	H	α-helix	trans	-62.9	-39.9	174.2	-163.7	0	0	0	0	111.5	Y253 C336 P337 A338 T344	Y253-S340 WeakPolarHBondContact CE2-OG 3.43Å; Y253-S340 PolarHBondContact OH-OG 3.11Å; Y253-S340 VanDerWaalsContact OH-OG 3.12Å; C336-S340 WeakPolarHBondContact O-CB 3.5Å; C336-S340 PolarHBondContact O-N 3.38Å; P337-S340 PolarHBondContact O-N 2.87Å; A338-S340 VanDerWaalsContact C-N 3.29Å; A338-S340 PolarHBondContact O-N 3.19Å; S340-T344 WeakPolarHBondContact O-CG2 3.39Å; S340-T344 PolarHBondContact O-N 3.19Å; S340-T344 VanDerWaalsContact O-N 3.07Å; S340-T344 PolarHBondContact O-OG1 3.44Å
341	N	72	Confident	73.8	Confident	107 Å²	107	44.2 Å²	44.2	57%	0.572	26%	0.257	S	S	*	.	H	α-helix	trans	-71	-32.1	178.4	-69.8	-14.8	0	0	0	113	P337 A338 C339 T344	P337-N341 VanDerWaalsContact O-CG 3.24Å; P337-N341 PolarHBondContact O-N 3.31Å; P337-N341 PolarHBondContact O-ND2 3.14Å; P337-N341 PolarHBondContact O-OD1 2.62Å; A338-N341 PolarHBondContact O-N 2.98Å; C339-N341 VanDerWaalsContact C-N 3.31Å; C339-N341 PolarHBondContact O-N 2.96Å; N341-T344 WeakPolarHBondContact CA-OG1 3.32Å; N341-T344 PolarHBondContact O-OG1 2.66Å
342	S	71.6	Confident	73.2	Confident	21 Å²	21	44.3 Å²	44.3	15%	0.147	26%	0.257	C	S	.	.	H	α-helix	trans	-69.4	-45.4	173.5	57.5	0	0	0	0	110.8	A338 C339 T344 N345 H346 F351	A338-S342 PolarHBondContact O-N 3.16Å; C339-S342 WeakPolarHBondContact CA-OG 3.39Å; C339-S342 PolarHBondContact O-N 3.38Å; C339-S342 PolarHBondContact O-OG 2.52Å; S342-T344 VanDerWaalsContact C-N 3.31Å; S342-T344 PolarHBondContact O-N 3.2Å; S342-N345 PolarHBondContact O-N 3.27Å; S342-H346 WeakPolarHBondContact O-CB 3.49Å; S342-H346 PolarHBondContact O-CD2 3.19Å; S342-H346 PolarHBondContact O-N 3.38Å; S342-F351 WeakPolarHBondContact OG-CD2 3.45Å; S342-F351 WeakPolarHBondContact OG-CE2 3.48Å
343	L	75.1	Confident	72.5	Confident	1 Å²	1	45.1 Å²	45.1	1%	0.005	26%	0.263	C	S	.	.	H	α-helix	trans	-64.5	-26.8	176.8	-82.8	150.6	0	0	0	114.4	Y253 L256 L335 C339 N345 H346 L348 F351 Y419	Y253-L343 WeakPolarHBondContact CB-O 3.48Å; Y253-L343 HydrophobicContact CD2-CB 3.95Å; L256-L343 HydrophobicContact CD1-CD2 4.13Å; L335-L343 HydrophobicContact CD1-CD1 3.52Å; L335-L343 HydrophobicContact CD2-CD1 3.55Å; L335-L343 HydrophobicContact CG-CD1 4.19Å; C339-L343 WeakPolarHBondContact O-CD1 3.32Å; C339-L343 PolarHBondContact O-N 3.16Å; C339-L343 VanDerWaalsContact O-N 3.09Å; L343-N345 PolarHBondContact O-N 3.4Å; L343-H346 PolarHBondContact O-N 2.87Å; L343-L348 HydrophobicContact CD2-CD1 4.37Å; L343-F351 HydrophobicContact CD1-CD1 3.99Å; L343-F351 HydrophobicContact CD1-CD2 3.82Å; L343-F351 HydrophobicContact CD1-CE1 4.07Å; L343-F351 HydrophobicContact CD1-CE2 3.89Å; L343-F351 HydrophobicContact CD1-CG 3.85Å; L343-F351 HydrophobicContact CD1-CZ 4.02Å; L343-F351 HydrophobicContact CD2-CB 3.54Å; L343-F351 HydrophobicContact CD2-CD1 4.11Å; L343-F351 HydrophobicContact CD2-CD2 4.26Å; L343-F351 HydrophobicContact CD2-CG 3.7Å; L343-F351 HydrophobicContact CG-CB 3.8Å; L343-F351 HydrophobicContact CG-CD1 4.13Å; L343-F351 HydrophobicContact CG-CD2 3.57Å; L343-F351 HydrophobicContact CG-CE2 4.15Å; L343-F351 HydrophobicContact CG-CG 3.54Å; L343-Y419 HydrophobicContact CD1-CE2 3.98Å
344	T	73.4	Confident	71.7	Confident	64 Å²	64	45.5 Å²	45.5	39%	0.393	26%	0.263	S	S	.	.	H	α-helix	trans	-63.3	-27.3	177.2	42	0	0	0	0	113.2	Y253 S340 N341 S342	Y253-T344 HydrophobicContact CD1-CG2 3.7Å; Y253-T344 HydrophobicContact CD2-CG2 4.11Å; Y253-T344 HydrophobicContact CE1-CG2 3.58Å; Y253-T344 HydrophobicContact CE2-CG2 4.01Å; Y253-T344 HydrophobicContact CG-CG2 3.96Å; S340-T344 WeakPolarHBondContact O-CG2 3.39Å; S340-T344 PolarHBondContact O-N 3.19Å; S340-T344 VanDerWaalsContact O-N 3.07Å; S340-T344 PolarHBondContact O-OG1 3.44Å; N341-T344 WeakPolarHBondContact CA-OG1 3.32Å; N341-T344 PolarHBondContact O-OG1 2.66Å; S342-T344 VanDerWaalsContact C-N 3.31Å; S342-T344 PolarHBondContact O-N 3.2Å
345	N	69.4	Low	70.5	Confident	133 Å²	133	50.4 Å²	50.4	71%	0.711	29%	0.291	S	S	*	.	H	α-helix	trans	-103.8	-6.2	-176.1	-63.9	-21.7	0	0	0	113.1	S342 L343	S342-N345 PolarHBondContact O-N 3.27Å; L343-N345 PolarHBondContact O-N 3.4Å
346	H	71.7	Confident	69.5	Low	82 Å²	82	54.5 Å²	54.5	38%	0.38	31%	0.313	S	S	.	.	S	Bend	trans	-139.9	151.1	-164.7	-75.6	-59	0	0	0	111	S342 L343 D350	S342-H346 WeakPolarHBondContact O-CB 3.49Å; S342-H346 PolarHBondContact O-CD2 3.19Å; S342-H346 PolarHBondContact O-N 3.38Å; L343-H346 PolarHBondContact O-N 2.87Å; H346-D350 HydrophobicContact CB-CB 3.7Å
347	S	73.2	Confident	68.2	Low	37 Å²	37	58.1 Å²	58.1	26%	0.259	34%	0.336	S	S	.	.			trans	-69	162.7	171.5	67.8	0	0	0	0	110.8	F349 D350 F351	S347-F349 PolarHBondContact O-N 3.2Å; S347-F349 VanDerWaalsContact O-N 3.17Å; S347-F349 PolarHBondContact OG-N 2.89Å; S347-D350 WeakPolarHBondContact CB-OD2 3.47Å; S347-D350 PolarHBondContact N-OD2 2.94Å; S347-D350 PolarHBondContact O-N 3.18Å; S347-D350 VanDerWaalsContact O-N 3.11Å; S347-D350 PolarHBondContact OG-N 3.26Å; S347-D350 PolarHBondContact OG-OD2 3.26Å; S347-F351 PolarHBondContact O-N 3.26Å
348	L	74.1	Confident	67.1	Low	0 Å²	0	55.3 Å²	55.3	0%	0	32%	0.315	C	S	.	.	H	α-helix	trans	-51.6	-36.2	170	-177.5	68.7	0	0	0	111.8	F250 G251 L328 L343 F351 L352 Y419	F250-L348 HydrophobicContact CE1-CD2 4.42Å; G251-L348 VanDerWaalsContact O-CB 3.25Å; G251-L348 WeakPolarHBondContact O-CB 3.34Å; G251-L348 PolarHBondContact O-N 3.48Å; L328-L348 HydrophobicContact CD2-CD2 3.8Å; L343-L348 HydrophobicContact CD2-CD1 4.37Å; L348-F351 PolarHBondContact O-N 2.95Å; L348-L352 HydrophobicContact CG-CD1 4.48Å; L348-L352 WeakPolarHBondContact O-CG 3.38Å; L348-L352 PolarHBondContact O-N 3.07Å; L348-Y419 HydrophobicContact CD1-CD1 4.28Å; L348-Y419 HydrophobicContact CD1-CD2 3.25Å; L348-Y419 HydrophobicContact CD1-CE2 3.8Å; L348-Y419 HydrophobicContact CD1-CG 3.51Å
349	F	66.6	Low	65.9	Low	58 Å²	58	56.3 Å²	56.3	25%	0.254	31%	0.31	S	S	.	.	H	α-helix	trans	-63.1	-50.9	177.5	-59	-92.9	0	0	0	111.1	F250 S347 F351 L352 N353 F411	F250-F349 HydrophobicContact CD1-CE2 4.3Å; F250-F349 HydrophobicContact CD1-CZ 4.17Å; F250-F349 HydrophobicContact CE1-CZ 4.28Å; S347-F349 PolarHBondContact O-N 3.2Å; S347-F349 VanDerWaalsContact O-N 3.17Å; S347-F349 PolarHBondContact OG-N 2.89Å; F349-F351 VanDerWaalsContact C-N 3.3Å; F349-F351 PolarHBondContact O-N 3.39Å; F349-L352 PolarHBondContact O-N 2.75Å; F349-N353 WeakPolarHBondContact O-CB 3.25Å; F349-N353 PolarHBondContact O-N 3.41Å; F349-N353 PolarHBondContact O-ND2 3.22Å; F349-F411 HydrophobicContact CE1-CE1 4.01Å
350	D	70.5	Confident	64.5	Low	69 Å²	69	59 Å²	59	37%	0.369	32%	0.324	S	S	.	.	H	α-helix	trans	-61.8	-40.1	176.6	-58.4	-38.2	0	0	0	110.7	H346 S347 L352 N353 N354	H346-D350 HydrophobicContact CB-CB 3.7Å; S347-D350 WeakPolarHBondContact CB-OD2 3.47Å; S347-D350 PolarHBondContact N-OD2 2.94Å; S347-D350 PolarHBondContact O-N 3.18Å; S347-D350 VanDerWaalsContact O-N 3.11Å; S347-D350 PolarHBondContact OG-N 3.26Å; S347-D350 PolarHBondContact OG-OD2 3.26Å; D350-L352 VanDerWaalsContact C-N 3.34Å; D350-L352 PolarHBondContact O-N 3.27Å; D350-N353 CarbonylContact O-C 3.6Å; D350-N353 PolarHBondContact O-N 3.47Å; D350-N354 WeakPolarHBondContact O-CB 3.24Å; D350-N354 PolarHBondContact O-N 3.09Å; D350-N354 PolarHBondContact O-OD1 2.93Å; D350-N354 VanDerWaalsContact O-OD1 3.09Å
351	F	73.1	Confident	62.9	Low	3 Å²	3	62.2 Å²	62.2	1%	0.013	34%	0.339	C	S	.	.	H	α-helix	trans	-63.1	-37.2	176.2	174.4	-101.9	0	0	0	113.6	L335 C339 S342 L343 S347 L348 F349 Y419 K422	L335-F351 HydrophobicContact CD2-CZ 4.18Å; C339-F351 HydrophobicContact CB-CE2 3.72Å; C339-F351 HydrophobicContact CB-CZ 3.86Å; S342-F351 WeakPolarHBondContact OG-CD2 3.45Å; S342-F351 WeakPolarHBondContact OG-CE2 3.48Å; L343-F351 HydrophobicContact CD1-CD1 3.99Å; L343-F351 HydrophobicContact CD1-CD2 3.82Å; L343-F351 HydrophobicContact CD1-CE1 4.07Å; L343-F351 HydrophobicContact CD1-CE2 3.89Å; L343-F351 HydrophobicContact CD1-CG 3.85Å; L343-F351 HydrophobicContact CD1-CZ 4.02Å; L343-F351 HydrophobicContact CD2-CB 3.54Å; L343-F351 HydrophobicContact CD2-CD1 4.11Å; L343-F351 HydrophobicContact CD2-CD2 4.26Å; L343-F351 HydrophobicContact CD2-CG 3.7Å; L343-F351 HydrophobicContact CG-CB 3.8Å; L343-F351 HydrophobicContact CG-CD1 4.13Å; L343-F351 HydrophobicContact CG-CD2 3.57Å; L343-F351 HydrophobicContact CG-CE2 4.15Å; L343-F351 HydrophobicContact CG-CG 3.54Å; S347-F351 PolarHBondContact O-N 3.26Å; L348-F351 PolarHBondContact O-N 2.95Å; F349-F351 VanDerWaalsContact C-N 3.3Å; F349-F351 PolarHBondContact O-N 3.39Å; F351-Y419 HydrophobicContact CD1-CD2 4.04Å; F351-Y419 HydrophobicContact CD1-CE2 4.38Å; F351-Y419 AromaticContact CE1-CD2 3.87Å; F351-Y419 HydrophobicContact CE1-CD2 3.87Å; F351-Y419 HydrophobicContact CE1-CE2 4.12Å; F351-K422 HydrophobicContact CD1-CD 4.42Å; F351-K422 HydrophobicContact CE1-CD 3.74Å; F351-K422 HydrophobicContact CE1-CG 4.32Å; F351-K422 HydrophobicContact CZ-CD 4.1Å; F351-K422 PolarHBondContact O-NZ 3Å
352	L	74.1	Confident	61.5	Low	2 Å²	2	62.1 Å²	62.1	1%	0.01	33%	0.334	C	S	.	.	H	α-helix	trans	-69.5	-44.3	173.3	-71.8	174.6	0	0	0	110.3	L348 F349 D350 Q415 L418 K422 L495 N498	L348-L352 HydrophobicContact CG-CD1 4.48Å; L348-L352 WeakPolarHBondContact O-CG 3.38Å; L348-L352 PolarHBondContact O-N 3.07Å; F349-L352 PolarHBondContact O-N 2.75Å; D350-L352 VanDerWaalsContact C-N 3.34Å; D350-L352 PolarHBondContact O-N 3.27Å; L352-Q415 HydrophobicContact CD1-CB 4.05Å; L352-Q415 HydrophobicContact CD1-CG 4.31Å; L352-L418 HydrophobicContact CD2-CB 4.23Å; L352-K422 HydrophobicContact CD2-CD 4.21Å; L352-L495 HydrophobicContact CD1-CD2 4.12Å; L352-N498 PolarHBondContact O-ND2 3.33Å
353	N	69.2	Low	60	Low	42 Å²	42	63.6 Å²	63.6	23%	0.225	34%	0.34	C	S	.	.	H	α-helix	trans	-81.4	-10.7	-175.5	-66.1	-19.2	0	0	0	114.9	F349 D350 D355	F349-N353 WeakPolarHBondContact O-CB 3.25Å; F349-N353 PolarHBondContact O-N 3.41Å; F349-N353 PolarHBondContact O-ND2 3.22Å; D350-N353 CarbonylContact O-C 3.6Å; D350-N353 PolarHBondContact O-N 3.47Å; N353-D355 PolarHBondContact O-N 3.49Å
354	N	65.9	Low	58.2	Low	54 Å²	54	70.3 Å²	70.3	29%	0.289	37%	0.369	S	S	.	.			trans	-64.7	112	174.6	-79.1	-10.5	0	0	0	109.3	D350 D356	D350-N354 WeakPolarHBondContact O-CB 3.24Å; D350-N354 PolarHBondContact O-N 3.09Å; D350-N354 PolarHBondContact O-OD1 2.93Å; D350-N354 VanDerWaalsContact O-OD1 3.09Å; N354-D356 PolarHBondContact O-N 2.69Å
355	D	52.8	Low	56.3	Low	125 Å²	125	70.9 Å²	70.9	67%	0.668	37%	0.369	S	S	*	.			trans	-68.3	59.6	164.1	-65.1	-34.4	0	0	0	109.5	N353 P357	N353-D355 PolarHBondContact O-N 3.49Å; D355-P357 WeakPolarHBondContact O-CD 3.48Å; D355-P357 VanDerWaalsContact O-N 3.07Å
356	D	53.8	Low	54.8	Low	103 Å²	103	68 Å²	68	55%	0.551	35%	0.35	S	S	*	.			trans	-61.5	115.3	158.9	-79.5	-30.7	0	0	0	104.9	N354 I358	N354-D356 PolarHBondContact O-N 2.69Å; D356-I358 PolarHBondContact O-N 3.09Å
357	P	44.9	Very low	53	Low	109 Å²	109	69.4 Å²	69.4	71%	0.708	37%	0.37	S	S	*	.			trans	-55.4	122.8	-177.6	21.6	-31	0	0	0	106.5	D355 D359	D355-P357 WeakPolarHBondContact O-CD 3.48Å; D355-P357 VanDerWaalsContact O-N 3.07Å; P357-D359 PolarHBondContact O-N 3.37Å
358	I	44.9	Very low	50.8	Low	48 Å²	48	70.3 Å²	70.3	25%	0.246	38%	0.376	C	S	.	.			trans	-63.1	87	160.4	-58.9	174.8	0	0	0	104	D356 D360 L363 Y426 I501	D356-I358 PolarHBondContact O-N 3.09Å; I358-D360 PolarHBondContact O-N 2.88Å; I358-L363 HydrophobicContact CG2-CD1 4.43Å; I358-L363 HydrophobicContact CG2-CG 4.33Å; I358-Y426 VanDerWaalsContact CD1-OH 3.27Å; I358-Y426 WeakPolarHBondContact CD1-OH 3.49Å; I358-Y426 HydrophobicContact CG1-CE1 4.49Å; I358-Y426 VanDerWaalsContact CG1-OH 3.24Å; I358-Y426 WeakPolarHBondContact CG1-OH 3.42Å; I358-I501 HydrophobicContact CD1-CB 4.3Å; I358-I501 HydrophobicContact CD1-CD1 3.45Å; I358-I501 VanDerWaalsContact CD1-CD1 3.45Å; I358-I501 HydrophobicContact CD1-CG1 3.51Å; I358-I501 HydrophobicContact CD1-CG2 3.77Å; I358-I501 HydrophobicContact CG1-CD1 4.49Å
359	D	41.3	Very low	48.6	Very low	91 Å²	91	74.8 Å²	74.8	49%	0.487	40%	0.403	S	S	.	.			trans	-57.6	127.3	172.1	-152.3	20.5	0	0	0	104.4	P357 N361 F362	P357-D359 PolarHBondContact O-N 3.37Å; D359-N361 HydrophobicContact CB-CB 4.35Å; D359-N361 CarbonylContact O-C 3.56Å; D359-N361 PolarHBondContact O-N 3.17Å; D359-N361 PolarHBondContact OD2-ND2 2.99Å; D359-F362 WeakPolarHBondContact O-CB 3.49Å; D359-F362 PolarHBondContact O-N 3.19Å
360	D	42.8	Very low	46.9	Very low	75 Å²	75	77.3 Å²	77.3	40%	0.401	43%	0.426	S	S	.	.	H	α-helix	trans	-53	-18.8	176	-90.2	-27.4	0	0	0	111.4	I358 Q542	I358-D360 PolarHBondContact O-N 2.88Å; D360-Q542 PolarHBondContact OD2-NE2 3.27Å
361	N	40.1	Very low	44.9	Very low	82 Å²	82	79.2 Å²	79.2	44%	0.439	44%	0.436	S	S	.	.	H	α-helix	trans	-64.6	-33	169.3	-66.8	-34.7	0	0	0	113.7	D359 K364 I365	D359-N361 HydrophobicContact CB-CB 4.35Å; D359-N361 CarbonylContact O-C 3.56Å; D359-N361 PolarHBondContact O-N 3.17Å; D359-N361 PolarHBondContact OD2-ND2 2.99Å; N361-K364 CarbonylContact O-C 3.54Å; N361-K364 WeakPolarHBondContact O-CA 3.27Å; N361-K364 WeakPolarHBondContact O-CB 3.24Å; N361-K364 PolarHBondContact O-N 3.06Å; N361-K364 VanDerWaalsContact O-N 3.15Å; N361-I365 HydrophobicContact CB-CD1 4.26Å; N361-I365 WeakPolarHBondContact O-CB 3.4Å; N361-I365 WeakPolarHBondContact O-CD1 3.43Å; N361-I365 WeakPolarHBondContact O-CG1 3.34Å; N361-I365 PolarHBondContact O-N 3.48Å
362	F	42.4	Very low	43.1	Very low	105 Å²	105	87.3 Å²	87.3	46%	0.461	47%	0.473	S	S	.	.	H	α-helix	trans	-73	-38	-177.4	-136.6	-84.8	0	0	0	113	D359 K364 I365 K366	D359-F362 WeakPolarHBondContact O-CB 3.49Å; D359-F362 PolarHBondContact O-N 3.19Å; F362-K364 PolarHBondContact O-N 3.07Å; F362-I365 PolarHBondContact O-N 3.4Å; F362-I365 VanDerWaalsContact O-N 3.14Å; F362-K366 PolarHBondContact O-N 3.01Å
363	L	41	Very low	41.1	Very low	53 Å²	53	92.3 Å²	92.3	28%	0.277	51%	0.508	S	S	.	.	H	α-helix	trans	-59.2	-31.3	168.4	-75.1	170.2	0	0	0	111.4	I358 F425	I358-L363 HydrophobicContact CG2-CD1 4.43Å; I358-L363 HydrophobicContact CG2-CG 4.33Å; L363-F425 HydrophobicContact CD2-CZ 4.14Å
364	K	35.9	Very low	39.6	Very low	142 Å²	142	94.3 Å²	94.3	62%	0.617	52%	0.524	S	S	*	.	H	α-helix	trans	-79	-36.8	172.5	-67.2	173.4	-177.5	167.8	0	113	N361 F362 K366 S367	N361-K364 CarbonylContact O-C 3.54Å; N361-K364 WeakPolarHBondContact O-CA 3.27Å; N361-K364 WeakPolarHBondContact O-CB 3.24Å; N361-K364 PolarHBondContact O-N 3.06Å; N361-K364 VanDerWaalsContact O-N 3.15Å; F362-K364 PolarHBondContact O-N 3.07Å; K364-K366 VanDerWaalsContact C-N 3.29Å; K364-K366 PolarHBondContact O-N 3.36Å; K364-S367 WeakPolarHBondContact O-CB 3.3Å; K364-S367 PolarHBondContact O-N 2.99Å; K364-S367 VanDerWaalsContact O-N 3.08Å; K364-S367 PolarHBondContact O-OG 3.48Å
365	I	34.5	Very low	38.3	Very low	76 Å²	76	95.5 Å²	95.5	39%	0.39	54%	0.536	S	S	.	.	H	α-helix	trans	-68.9	-22.9	-175.8	-70.9	158.2	0	0	0	112.3	N361 F362 S367 S368	N361-I365 HydrophobicContact CB-CD1 4.26Å; N361-I365 WeakPolarHBondContact O-CB 3.4Å; N361-I365 WeakPolarHBondContact O-CD1 3.43Å; N361-I365 WeakPolarHBondContact O-CG1 3.34Å; N361-I365 PolarHBondContact O-N 3.48Å; F362-I365 PolarHBondContact O-N 3.4Å; F362-I365 VanDerWaalsContact O-N 3.14Å; I365-S367 PolarHBondContact O-N 3.42Å; I365-S368 WeakPolarHBondContact CA-OG 3.3Å; I365-S368 CarbonylContact O-C 3.57Å; I365-S368 WeakPolarHBondContact O-CA 3.27Å; I365-S368 PolarHBondContact O-N 2.88Å; I365-S368 PolarHBondContact O-OG 3.16Å; I365-S368 VanDerWaalsContact O-OG 3.07Å
366	K	37.7	Very low	38.2	Very low	72 Å²	72	94.1 Å²	94.1	31%	0.313	54%	0.536	S	S	.	.	T	Hydrogen-bonded Turn	trans	-59.4	-17.6	169.9	-108	-168	179.1	-173.1	0	114.2	F362 K364 S368 F425	F362-K366 PolarHBondContact O-N 3.01Å; K364-K366 VanDerWaalsContact C-N 3.29Å; K364-K366 PolarHBondContact O-N 3.36Å; K366-S368 VanDerWaalsContact C-N 3.32Å; K366-F425 WeakPolarHBondContact CE-O 3.4Å; K366-F425 PolarHBondContact NZ-O 2.87Å
367	S	33.6	Very low	38.1	Very low	112 Å²	112	92.6 Å²	92.6	78%	0.783	53%	0.534	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81	-9.8	171.2	70.9	0	0	0	0	113.9	K364 I365	K364-S367 WeakPolarHBondContact O-CB 3.3Å; K364-S367 PolarHBondContact O-N 2.99Å; K364-S367 VanDerWaalsContact O-N 3.08Å; K364-S367 PolarHBondContact O-OG 3.48Å; I365-S367 PolarHBondContact O-N 3.42Å
368	S	27.3	Very low	38.7	Very low	56 Å²	56	90.1 Å²	90.1	39%	0.392	52%	0.519	S	S	.	.	S	Bend	trans	-133.1	115.8	-171.6	57.6	0	0	0	0	111.8	I365 K366	I365-S368 WeakPolarHBondContact CA-OG 3.3Å; I365-S368 CarbonylContact O-C 3.57Å; I365-S368 WeakPolarHBondContact O-CA 3.27Å; I365-S368 PolarHBondContact O-N 2.88Å; I365-S368 PolarHBondContact O-OG 3.16Å; I365-S368 VanDerWaalsContact O-OG 3.07Å; K366-S368 VanDerWaalsContact C-N 3.32Å
369	T	28	Very low	40	Very low	93 Å²	93	89.1 Å²	89.1	57%	0.571	52%	0.515	S	S	*	.			trans	95.3	95	168.3	70	0	0	0	0	117.9	N371	T369-N371 PolarHBondContact O-N 3.38Å; T369-N371 VanDerWaalsContact O-N 3.14Å
370	P	30.6	Very low	41.8	Very low	112 Å²	112	86.6 Å²	86.6	73%	0.727	50%	0.499	S	S	*	.			trans	-73.5	94.7	156.1	29.1	-28.9	0	0	0	108.7	H372	P370-H372 PolarHBondContact O-N 2.84Å
371	N	30	Very low	43.5	Very low	109 Å²	109	86.9 Å²	86.9	58%	0.583	50%	0.501	S	S	*	.			trans	-75.4	120.7	167.8	-82.2	-16.9	0	0	0	109.5	T369 N429	T369-N371 PolarHBondContact O-N 3.38Å; T369-N371 VanDerWaalsContact O-N 3.14Å; N371-N429 PolarHBondContact O-ND2 3.38Å
372	H	33.5	Very low	45.7	Very low	173 Å²	173	83.4 Å²	83.4	80%	0.801	48%	0.482	S	S	*	.			trans	28.4	103	164.1	-67.4	-69.3	0	0	0	117.8	P370 P374	P370-H372 PolarHBondContact O-N 2.84Å; H372-P374 WeakPolarHBondContact O-CD 3.44Å
373	S	33.1	Very low	47.7	Very low	107 Å²	107	78.4 Å²	78.4	75%	0.748	46%	0.46	S	S	*	.			trans	-40.5	117.5	164.6	51.2	0	0	0	0	115
374	P	36.9	Very low	49.8	Very low	84 Å²	84	76.9 Å²	76.9	55%	0.545	45%	0.452	S	S	.	.	S	Bend	trans	-64.2	147.1	131.8	-0.6	19.3	0	0	0	107.4	H372 S376 T379	H372-P374 WeakPolarHBondContact O-CD 3.44Å; P374-S376 PolarHBondContact O-N 3.37Å; P374-T379 HydrophobicContact CB-CG2 3.89Å; P374-T379 HydrophobicContact CG-CG2 3.84Å
375	S	40	Very low	52.3	Low	78 Å²	78	70.4 Å²	70.4	55%	0.545	42%	0.424	S	S	.	.			trans	-39.6	114.7	174.9	38	0	0	0	0	111	S377 S378	S375-S377 PolarHBondContact O-N 3.21Å; S375-S378 PolarHBondContact O-N 2.79Å; S375-S378 PolarHBondContact O-OG 3.05Å; S375-S378 PolarHBondContact OG-OG 3.28Å; S375-S378 VanDerWaalsContact OG-OG 3.07Å
376	S	50.8	Low	54.9	Low	97 Å²	97	66.8 Å²	66.8	68%	0.678	41%	0.405	S	S	*	.	H	α-helix	trans	-55.5	-23.8	-168.4	50	0	0	0	0	114.3	P374 T379 Y380	P374-S376 PolarHBondContact O-N 3.37Å; S376-T379 PolarHBondContact O-OG1 3.23Å; S376-Y380 WeakPolarHBondContact O-CB 3.24Å; S376-Y380 PolarHBondContact O-N 3.45Å
377	S	51.5	Low	57.4	Low	71 Å²	71	63.4 Å²	63.4	50%	0.497	39%	0.391	S	S	.	.	H	α-helix	trans	-66.1	-55.3	174.3	51.5	0	0	0	0	112.4	S375 T379 Y380 D381	S375-S377 PolarHBondContact O-N 3.21Å; S377-T379 VanDerWaalsContact C-N 3.28Å; S377-T379 PolarHBondContact O-N 2.86Å; S377-Y380 WeakPolarHBondContact O-CB 3.3Å; S377-Y380 PolarHBondContact O-N 3.34Å; S377-D381 PolarHBondContact O-N 3.43Å
378	S	57.4	Low	60.1	Low	57 Å²	57	58.8 Å²	58.8	40%	0.399	36%	0.357	S	S	.	.	H	α-helix	trans	-58.2	-37.7	-175.9	58.9	0	0	0	0	113.5	S375 L382	S375-S378 PolarHBondContact O-N 2.79Å; S375-S378 PolarHBondContact O-OG 3.05Å; S375-S378 PolarHBondContact OG-OG 3.28Å; S375-S378 VanDerWaalsContact OG-OG 3.07Å; S378-L382 PolarHBondContact O-N 2.97Å
379	T	72.7	Confident	63.3	Low	27 Å²	27	56.2 Å²	56.2	17%	0.166	34%	0.338	C	S	.	.	H	α-helix	trans	-70.7	-35.2	177.3	48.3	0	0	0	0	112.5	P374 S376 S377 L383 L430	P374-T379 HydrophobicContact CB-CG2 3.89Å; P374-T379 HydrophobicContact CG-CG2 3.84Å; S376-T379 PolarHBondContact O-OG1 3.23Å; S377-T379 VanDerWaalsContact C-N 3.28Å; S377-T379 PolarHBondContact O-N 2.86Å; T379-L383 WeakPolarHBondContact O-CB 3.44Å; T379-L383 PolarHBondContact O-N 3.34Å; T379-L383 VanDerWaalsContact O-N 3.14Å; T379-L430 HydrophobicContact CG2-CD2 4.39Å
380	Y	77.6	Confident	66.4	Low	37 Å²	37	51.8 Å²	51.8	15%	0.145	31%	0.311	C	S	.	.	H	α-helix	trans	-71.7	-44.7	179.4	179.6	-100.5	0	0	0	111	Y13 I17 S376 S377 L382 L383 L384 D432 I435	Y13-Y380 WeakPolarHBondContact CE1-OH 3.34Å; I17-Y380 HydrophobicContact CD1-CE1 4.35Å; I17-Y380 WeakPolarHBondContact CD1-OH 3.29Å; S376-Y380 WeakPolarHBondContact O-CB 3.24Å; S376-Y380 PolarHBondContact O-N 3.45Å; S377-Y380 WeakPolarHBondContact O-CB 3.3Å; S377-Y380 PolarHBondContact O-N 3.34Å; Y380-L382 VanDerWaalsContact C-N 3.34Å; Y380-L382 PolarHBondContact O-N 3.5Å; Y380-L383 WeakPolarHBondContact O-CB 3.29Å; Y380-L383 PolarHBondContact O-N 2.98Å; Y380-L383 VanDerWaalsContact O-N 3.09Å; Y380-L384 HydrophobicContact CD1-CD1 3.87Å; Y380-L384 HydrophobicContact CD1-CG 4.11Å; Y380-L384 HydrophobicContact CE1-CD1 3.3Å; Y380-L384 HydrophobicContact CE1-CD2 4.01Å; Y380-L384 HydrophobicContact CE1-CG 3.71Å; Y380-L384 HydrophobicContact CE2-CD2 4.19Å; Y380-L384 HydrophobicContact CE2-CG 4.47Å; Y380-L384 WeakPolarHBondContact O-CG 3.33Å; Y380-L384 PolarHBondContact O-N 2.95Å; Y380-L384 WeakPolarHBondContact OH-CD2 3.31Å; Y380-D432 VanDerWaalsContact CD2-OD2 3.26Å; Y380-D432 WeakPolarHBondContact CD2-OD2 3.38Å; Y380-I435 HydrophobicContact CD2-CD1 4.39Å; Y380-I435 HydrophobicContact CE2-CD1 3.53Å
381	D	79.8	Confident	69.4	Low	82 Å²	82	49.5 Å²	49.5	44%	0.439	29%	0.29	S	S	.	.	H	α-helix	trans	-61.9	-41.1	178.3	-61.8	-29.4	0	0	0	111.6	S377 L383 L384 F385	S377-D381 PolarHBondContact O-N 3.43Å; D381-L383 VanDerWaalsContact C-N 3.35Å; D381-L383 PolarHBondContact O-N 2.84Å; D381-L384 PolarHBondContact O-N 2.86Å; D381-F385 WeakPolarHBondContact O-CB 3.32Å; D381-F385 PolarHBondContact O-N 3.35Å
382	L	84.9	Confident	72.3	Confident	9 Å²	9	44.3 Å²	44.3	5%	0.047	26%	0.263	C	S	.	.	H	α-helix	trans	-63.7	-38.8	173.4	-176.6	62.4	0	0	0	112.4	I263 L272 I330 V333 W334 S378 Y380 F385 T386	I263-L382 HydrophobicContact CG2-CD1 3.81Å; I263-L382 HydrophobicContact CG2-CD2 4.17Å; L272-L382 HydrophobicContact CD1-CB 4.44Å; L272-L382 HydrophobicContact CD1-CD1 3.76Å; I330-L382 HydrophobicContact CG1-CD1 4.21Å; I330-L382 HydrophobicContact CG2-CD1 4.48Å; V333-L382 HydrophobicContact CB-CD2 4.08Å; V333-L382 HydrophobicContact CG1-CD2 3.6Å; W334-L382 HydrophobicContact CZ2-CD2 4.11Å; W334-L382 HydrophobicContact CZ2-CG 3.89Å; S378-L382 PolarHBondContact O-N 2.97Å; Y380-L382 VanDerWaalsContact C-N 3.34Å; Y380-L382 PolarHBondContact O-N 3.5Å; L382-F385 HydrophobicContact CD1-CD1 4.39Å; L382-F385 PolarHBondContact O-N 3.16Å; L382-T386 WeakPolarHBondContact O-CB 3.39Å; L382-T386 PolarHBondContact O-N 3.5Å; L382-T386 PolarHBondContact O-OG1 3.43Å
383	L	85	Confident	75.2	Confident	0 Å²	0	36.1 Å²	36.1	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-66.7	-41.4	176.6	-179.9	63.3	0	0	0	111.6	W334 T379 Y380 D381 T386 C387 L424 L430 D432 I435 I436	W334-L383 HydrophobicContact CH2-CD1 4.14Å; W334-L383 HydrophobicContact CZ2-CB 4.3Å; W334-L383 HydrophobicContact CZ2-CD1 4.31Å; T379-L383 WeakPolarHBondContact O-CB 3.44Å; T379-L383 PolarHBondContact O-N 3.34Å; T379-L383 VanDerWaalsContact O-N 3.14Å; Y380-L383 WeakPolarHBondContact O-CB 3.29Å; Y380-L383 PolarHBondContact O-N 2.98Å; Y380-L383 VanDerWaalsContact O-N 3.09Å; D381-L383 VanDerWaalsContact C-N 3.35Å; D381-L383 PolarHBondContact O-N 2.84Å; L383-T386 PolarHBondContact O-N 3.28Å; L383-C387 PolarHBondContact O-N 2.91Å; L383-L424 HydrophobicContact CD1-CD2 3.99Å; L383-L430 HydrophobicContact CD2-CD1 4.18Å; L383-D432 HydrophobicContact CD2-CB 3.94Å; L383-I435 HydrophobicContact CD1-CG2 4.11Å; L383-I435 HydrophobicContact CD2-CB 3.89Å; L383-I435 HydrophobicContact CD2-CD1 4.39Å; L383-I435 HydrophobicContact CD2-CG2 4.03Å; L383-I435 HydrophobicContact CG-CB 4.1Å; L383-I435 HydrophobicContact CG-CG2 3.64Å; L383-I436 HydrophobicContact CD1-CG1 3.99Å; L383-I436 HydrophobicContact CD2-CG1 3.93Å
384	L	84.3	Confident	78	Confident	20 Å²	20	31.2 Å²	31.2	11%	0.105	19%	0.19	C	C	.	.	H	α-helix	trans	-61.4	-46.7	173.2	-68.6	-174.4	0	0	0	111.6	F10 I14 Y380 D381 T386 C387 E388 I435	F10-L384 HydrophobicContact CE1-CD2 4.35Å; F10-L384 HydrophobicContact CE2-CD2 3.29Å; F10-L384 HydrophobicContact CE2-CG 4.48Å; F10-L384 HydrophobicContact CZ-CB 3.78Å; F10-L384 HydrophobicContact CZ-CD1 4.35Å; F10-L384 HydrophobicContact CZ-CD2 3.16Å; F10-L384 HydrophobicContact CZ-CG 3.91Å; I14-L384 HydrophobicContact CD1-CD1 4.33Å; I14-L384 HydrophobicContact CG1-CD1 4.47Å; Y380-L384 HydrophobicContact CD1-CD1 3.87Å; Y380-L384 HydrophobicContact CD1-CG 4.11Å; Y380-L384 HydrophobicContact CE1-CD1 3.3Å; Y380-L384 HydrophobicContact CE1-CD2 4.01Å; Y380-L384 HydrophobicContact CE1-CG 3.71Å; Y380-L384 HydrophobicContact CE2-CD2 4.19Å; Y380-L384 HydrophobicContact CE2-CG 4.47Å; Y380-L384 WeakPolarHBondContact O-CG 3.33Å; Y380-L384 PolarHBondContact O-N 2.95Å; Y380-L384 WeakPolarHBondContact OH-CD2 3.31Å; D381-L384 PolarHBondContact O-N 2.86Å; L384-T386 VanDerWaalsContact C-N 3.3Å; L384-T386 PolarHBondContact O-N 2.93Å; L384-C387 WeakPolarHBondContact O-CB 3.49Å; L384-C387 PolarHBondContact O-N 3.35Å; L384-E388 PolarHBondContact O-N 3.02Å; L384-E388 VanDerWaalsContact O-N 3.09Å; L384-I435 HydrophobicContact CD2-CD1 3.59Å
385	F	88.8	Confident	80.5	Confident	7 Å²	7	29.3 Å²	29.3	3%	0.031	18%	0.175	C	C	.	.	H	α-helix	trans	-56.4	-46.3	175.4	172.4	-102.5	0	0	0	111.3	L272 L275 L326 I330 D381 L382 C387 E388 L389	L272-F385 HydrophobicContact CB-CB 4.14Å; L272-F385 HydrophobicContact CB-CD2 3.81Å; L272-F385 HydrophobicContact CB-CE2 4.45Å; L272-F385 HydrophobicContact CB-CG 3.94Å; L272-F385 HydrophobicContact CD1-CB 4.19Å; L272-F385 HydrophobicContact CD1-CD1 4.45Å; L272-F385 HydrophobicContact CD1-CG 4.28Å; L272-F385 HydrophobicContact CD2-CD1 3.91Å; L272-F385 HydrophobicContact CD2-CD2 4.23Å; L272-F385 HydrophobicContact CD2-CE1 3.97Å; L272-F385 HydrophobicContact CD2-CE2 4.33Å; L272-F385 HydrophobicContact CD2-CG 4.05Å; L272-F385 HydrophobicContact CD2-CZ 4.21Å; L272-F385 HydrophobicContact CG-CG 4.31Å; L272-F385 VanDerWaalsContact O-CD2 3.3Å; L272-F385 WeakPolarHBondContact O-CD2 3.32Å; L275-F385 HydrophobicContact CB-CE2 4.06Å; L275-F385 HydrophobicContact CD2-CE2 3.85Å; L275-F385 HydrophobicContact CD2-CZ 3.53Å; L275-F385 HydrophobicContact CG-CE2 3.9Å; L275-F385 HydrophobicContact CG-CZ 4.03Å; L326-F385 HydrophobicContact CD2-CE1 4.48Å; L326-F385 HydrophobicContact CD2-CZ 4.43Å; I330-F385 HydrophobicContact CD1-CD1 4.09Å; I330-F385 HydrophobicContact CD1-CE1 3.88Å; D381-F385 WeakPolarHBondContact O-CB 3.32Å; D381-F385 PolarHBondContact O-N 3.35Å; L382-F385 HydrophobicContact CD1-CD1 4.39Å; L382-F385 PolarHBondContact O-N 3.16Å; F385-C387 VanDerWaalsContact C-N 3.3Å; F385-C387 PolarHBondContact O-N 2.8Å; F385-E388 PolarHBondContact O-N 2.88Å; F385-L389 HydrophobicContact CE1-CD2 4.25Å; F385-L389 HydrophobicContact CZ-CD1 4.48Å; F385-L389 WeakPolarHBondContact O-CB 3.48Å; F385-L389 PolarHBondContact O-N 3.49Å
386	T	90.3	Very high	82.9	Confident	0 Å²	0	25.6 Å²	25.6	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-61	-40.5	179.4	-56.2	0	0	0	0	111.8	I330 W334 L382 L383 L384 L389 L390 L420	I330-T386 HydrophobicContact CD1-CG2 4.46Å; I330-T386 HydrophobicContact CG2-CG2 4.3Å; I330-T386 WeakPolarHBondContact CG2-OG1 3.13Å; W334-T386 HydrophobicContact CH2-CG2 3.81Å; W334-T386 WeakPolarHBondContact CH2-OG1 3.48Å; W334-T386 HydrophobicContact CZ3-CG2 4.01Å; L382-T386 WeakPolarHBondContact O-CB 3.39Å; L382-T386 PolarHBondContact O-N 3.5Å; L382-T386 PolarHBondContact O-OG1 3.43Å; L383-T386 PolarHBondContact O-N 3.28Å; L384-T386 VanDerWaalsContact C-N 3.3Å; L384-T386 PolarHBondContact O-N 2.93Å; T386-L389 PolarHBondContact O-N 3.33Å; T386-L390 HydrophobicContact CG2-CD1 3.99Å; T386-L390 HydrophobicContact CG2-CG 4.46Å; T386-L390 WeakPolarHBondContact O-CB 3.26Å; T386-L390 VanDerWaalsContact O-CG 3.23Å; T386-L390 WeakPolarHBondContact O-CG 3.5Å; T386-L390 PolarHBondContact O-N 3.45Å; T386-L420 HydrophobicContact CG2-CD2 4.12Å
387	C	90.3	Very high	84.7	Confident	1 Å²	1	21.2 Å²	21.2	1%	0.007	12%	0.118	C	C	.	.	H	α-helix	trans	-62.1	-46.9	176.5	-168.6	0	0	0	0	111.8	L383 L384 F385 L390 K391 I435	L383-C387 PolarHBondContact O-N 2.91Å; L384-C387 WeakPolarHBondContact O-CB 3.49Å; L384-C387 PolarHBondContact O-N 3.35Å; F385-C387 VanDerWaalsContact C-N 3.3Å; F385-C387 PolarHBondContact O-N 2.8Å; C387-L390 PolarHBondContact O-N 3.5Å; C387-K391 WeakPolarHBondContact O-CB 3.48Å; C387-K391 PolarHBondContact O-N 2.95Å; C387-I435 HydrophobicContact CB-CG2 3.94Å
388	E	90	Very high	86.3	Confident	15 Å²	15	21.1 Å²	21.1	7%	0.07	11%	0.11	C	C	.	.	H	α-helix	trans	-70	-34.4	178.7	-72.2	-65.7	135.3	0	0	112.7	F10 N280 L384 F385 K391 S392	F10-E388 HydrophobicContact CD1-CG 4.01Å; F10-E388 WeakPolarHBondContact CD1-OE1 3.2Å; F10-E388 HydrophobicContact CE1-CG 3.57Å; F10-E388 HydrophobicContact CZ-CG 4.32Å; N280-E388 PolarHBondContact ND2-OE2 3.49Å; N280-E388 VanDerWaalsContact ND2-OE2 3.07Å; L384-E388 PolarHBondContact O-N 3.02Å; L384-E388 VanDerWaalsContact O-N 3.09Å; F385-E388 PolarHBondContact O-N 2.88Å; E388-K391 IonicContact OE1-NZ 2.87Å; E388-K391 PolarHBondContact OE1-NZ 3.39Å; E388-K391 IonicContact OE2-NZ 3.38Å; E388-K391 PolarHBondContact OE2-NZ 2.64Å; E388-S392 WeakPolarHBondContact O-CB 3.32Å; E388-S392 PolarHBondContact O-N 2.88Å; E388-S392 PolarHBondContact O-OG 2.89Å
389	L	93.4	Very high	87.6	Confident	1 Å²	1	18.9 Å²	18.9	1%	0.005	9%	0.093	C	C	.	.	H	α-helix	trans	-59.3	-51.3	171.7	177.9	70.7	0	0	0	110.9	L279 F323 L326 I330 F385 T386 S392 L393	L279-L389 HydrophobicContact CD1-CD1 3.6Å; F323-L389 HydrophobicContact CD1-CD1 3.56Å; F323-L389 HydrophobicContact CD1-CG 4.3Å; F323-L389 HydrophobicContact CE1-CD1 3.61Å; L326-L389 HydrophobicContact CB-CD2 3.88Å; L326-L389 HydrophobicContact CD1-CD1 3.83Å; L326-L389 HydrophobicContact CD1-CD2 4.5Å; I330-L389 HydrophobicContact CD1-CD2 3.67Å; F385-L389 HydrophobicContact CE1-CD2 4.25Å; F385-L389 HydrophobicContact CZ-CD1 4.48Å; F385-L389 WeakPolarHBondContact O-CB 3.48Å; F385-L389 PolarHBondContact O-N 3.49Å; T386-L389 PolarHBondContact O-N 3.33Å; L389-S392 WeakPolarHBondContact O-CB 3.42Å; L389-S392 PolarHBondContact O-N 3.28Å; L389-L393 WeakPolarHBondContact O-CB 3.12Å; L389-L393 PolarHBondContact O-N 3.49Å
390	L	94.4	Very high	88	Confident	0 Å²	0	22 Å²	22	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-65.1	-40.6	-179.6	-70.8	168.4	0	0	0	111.8	T386 C387 L393 L394 L417 L420 C439 Y442 I443 I446	T386-L390 HydrophobicContact CG2-CD1 3.99Å; T386-L390 HydrophobicContact CG2-CG 4.46Å; T386-L390 WeakPolarHBondContact O-CB 3.26Å; T386-L390 VanDerWaalsContact O-CG 3.23Å; T386-L390 WeakPolarHBondContact O-CG 3.5Å; T386-L390 PolarHBondContact O-N 3.45Å; C387-L390 PolarHBondContact O-N 3.5Å; L390-L393 PolarHBondContact O-N 3.42Å; L390-L394 WeakPolarHBondContact O-CB 3.45Å; L390-L394 PolarHBondContact O-N 3.48Å; L390-L417 HydrophobicContact CD2-CD2 3.69Å; L390-L420 HydrophobicContact CD2-CD2 4.3Å; L390-C439 HydrophobicContact CD1-CB 3.74Å; L390-Y442 HydrophobicContact CB-CD2 4.3Å; L390-Y442 HydrophobicContact CB-CG 4.36Å; L390-I443 HydrophobicContact CD1-CD1 4.06Å; L390-I443 HydrophobicContact CD1-CG1 3.8Å; L390-I443 HydrophobicContact CD2-CD1 4.48Å; L390-I443 HydrophobicContact CD2-CG1 3.7Å; L390-I443 HydrophobicContact CG-CG1 4.41Å; L390-I446 HydrophobicContact CB-CD1 4.23Å; L390-I446 HydrophobicContact CD2-CD1 3.82Å; L390-I446 WeakPolarHBondContact O-CD1 3.42Å
391	K	93.2	Very high	88.1	Confident	64 Å²	64	22 Å²	22	28%	0.278	11%	0.114	S	C	.	.	H	α-helix	trans	-62.1	-42.3	174.5	180	-173.6	169.4	-156.9	0	112.1	C387 E388 L394 N395 Y442	C387-K391 WeakPolarHBondContact O-CB 3.48Å; C387-K391 PolarHBondContact O-N 2.95Å; E388-K391 IonicContact OE1-NZ 2.87Å; E388-K391 PolarHBondContact OE1-NZ 3.39Å; E388-K391 IonicContact OE2-NZ 3.38Å; E388-K391 PolarHBondContact OE2-NZ 2.64Å; K391-L394 PolarHBondContact O-N 3.33Å; K391-N395 PolarHBondContact O-N 3.28Å; K391-N395 VanDerWaalsContact O-N 3.12Å; K391-N395 PolarHBondContact O-ND2 2.93Å; K391-Y442 HydrophobicContact CB-CE1 4.46Å; K391-Y442 HydrophobicContact CB-CE2 4.12Å
392	S	91.5	Very high	88.2	Confident	1 Å²	1	18 Å²	18	1%	0.007	9%	0.093	C	C	.	.	H	α-helix	trans	-61.6	-49.1	174.1	-60.8	0	0	0	0	110.6	N280 E388 L389 L394 N395 L396	N280-S392 PolarHBondContact OD1-OG 3.3Å; E388-S392 WeakPolarHBondContact O-CB 3.32Å; E388-S392 PolarHBondContact O-N 2.88Å; E388-S392 PolarHBondContact O-OG 2.89Å; L389-S392 WeakPolarHBondContact O-CB 3.42Å; L389-S392 PolarHBondContact O-N 3.28Å; S392-L394 VanDerWaalsContact C-N 3.35Å; S392-L394 PolarHBondContact O-N 2.88Å; S392-N395 PolarHBondContact O-N 2.88Å; S392-L396 VanDerWaalsContact O-CG 3.29Å; S392-L396 WeakPolarHBondContact O-CG 3.35Å; S392-L396 PolarHBondContact O-N 3.37Å
393	L	92.5	Very high	87.9	Confident	0 Å²	0	19.4 Å²	19.4	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-58.7	-43.4	178.1	-178.7	58.9	0	0	0	112.4	F323 L389 L390 N395 L396 I397 F406 L413 L417 I446	F323-L393 HydrophobicContact CB-CD1 4.21Å; F323-L393 HydrophobicContact CD1-CB 3.97Å; F323-L393 HydrophobicContact CD1-CD1 3.97Å; F323-L393 HydrophobicContact CD1-CD2 4.42Å; F323-L393 HydrophobicContact CD1-CG 4.34Å; F323-L393 HydrophobicContact CD2-CD1 4.38Å; F323-L393 HydrophobicContact CE1-CB 4.05Å; F323-L393 HydrophobicContact CE1-CD1 4.44Å; F323-L393 HydrophobicContact CG-CD1 3.93Å; L389-L393 WeakPolarHBondContact O-CB 3.12Å; L389-L393 PolarHBondContact O-N 3.49Å; L390-L393 PolarHBondContact O-N 3.42Å; L393-N395 PolarHBondContact O-N 3.47Å; L393-L396 PolarHBondContact O-N 2.85Å; L393-I397 HydrophobicContact CD1-CD1 3.7Å; L393-I397 HydrophobicContact CD1-CG1 4.11Å; L393-I397 HydrophobicContact CG-CD1 3.76Å; L393-I397 WeakPolarHBondContact O-CG1 3.49Å; L393-I397 PolarHBondContact O-N 3.39Å; L393-F406 HydrophobicContact CD1-CE1 3.92Å; L393-F406 HydrophobicContact CD1-CZ 4.12Å; L393-L413 HydrophobicContact CD2-CD1 4.19Å; L393-L417 HydrophobicContact CD2-CD2 4.32Å; L393-I446 HydrophobicContact CB-CD1 4.27Å; L393-I446 HydrophobicContact CD2-CD1 4.08Å; L393-I446 HydrophobicContact CD2-CG2 4.32Å; L393-I446 HydrophobicContact CG-CD1 4.19Å; L393-I446 HydrophobicContact CG-CG2 4.46Å
394	L	92.3	Very high	87.4	Confident	4 Å²	4	24 Å²	24	2%	0.021	13%	0.126	C	C	.	.	H	α-helix	trans	-58.7	-47.6	175.9	178	61.3	0	0	0	111.6	L390 K391 S392 L396 I397 Q398 Y442 R445 I446	L390-L394 WeakPolarHBondContact O-CB 3.45Å; L390-L394 PolarHBondContact O-N 3.48Å; K391-L394 PolarHBondContact O-N 3.33Å; S392-L394 VanDerWaalsContact C-N 3.35Å; S392-L394 PolarHBondContact O-N 2.88Å; L394-L396 VanDerWaalsContact C-N 3.32Å; L394-L396 PolarHBondContact O-N 3.21Å; L394-I397 PolarHBondContact O-N 3.08Å; L394-Q398 HydrophobicContact CD1-CG 4.5Å; L394-Q398 VanDerWaalsContact O-CG 3.31Å; L394-Q398 WeakPolarHBondContact O-CG 3.37Å; L394-Q398 PolarHBondContact O-N 3.17Å; L394-Y442 HydrophobicContact CD2-CD1 3.75Å; L394-Y442 HydrophobicContact CD2-CE1 4.21Å; L394-R445 HydrophobicContact CD1-CB 4.01Å; L394-R445 HydrophobicContact CD2-CB 4.3Å; L394-I446 HydrophobicContact CB-CD1 4.32Å; L394-I446 HydrophobicContact CB-CG1 3.79Å; L394-I446 HydrophobicContact CD1-CG1 3.99Å; L394-I446 HydrophobicContact CG-CG1 4.46Å
395	N	90.9	Very high	87.1	Confident	45 Å²	45	24.5 Å²	24.5	24%	0.241	13%	0.127	C	C	.	.	H	α-helix	trans	-61.9	-41.6	178	-71.1	-23.9	0	0	0	111.3	T283 M287 K391 S392 L393 Q398 I399	T283-N395 HydrophobicContact CG2-CB 3.45Å; T283-N395 VanDerWaalsContact CG2-CB 3.45Å; M287-N395 HydrophobicContact SD-CB 4.01Å; K391-N395 PolarHBondContact O-N 3.28Å; K391-N395 VanDerWaalsContact O-N 3.12Å; K391-N395 PolarHBondContact O-ND2 2.93Å; S392-N395 PolarHBondContact O-N 2.88Å; L393-N395 PolarHBondContact O-N 3.47Å; N395-Q398 PolarHBondContact O-N 3.35Å; N395-I399 WeakPolarHBondContact O-CG1 3.31Å
396	L	90.2	Very high	86.6	Confident	0 Å²	0	24.5 Å²	24.5	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-64.9	-43.6	179.5	-68.3	175.9	0	0	0	112.7	T283 L286 I319 F323 S392 L393 L394 Q398 I399 L402 F406	T283-L396 HydrophobicContact CG2-CD2 4.24Å; T283-L396 HydrophobicContact CG2-CG 4.39Å; L286-L396 HydrophobicContact CB-CD2 4.25Å; L286-L396 HydrophobicContact CD1-CD2 3.39Å; L286-L396 HydrophobicContact CG-CD2 4.44Å; I319-L396 HydrophobicContact CD1-CD1 4.11Å; F323-L396 HydrophobicContact CE1-CD1 4.37Å; F323-L396 HydrophobicContact CE2-CD1 3.62Å; F323-L396 HydrophobicContact CZ-CD1 3.4Å; F323-L396 VanDerWaalsContact CZ-CD1 3.4Å; S392-L396 VanDerWaalsContact O-CG 3.29Å; S392-L396 WeakPolarHBondContact O-CG 3.35Å; S392-L396 PolarHBondContact O-N 3.37Å; L393-L396 PolarHBondContact O-N 2.85Å; L394-L396 VanDerWaalsContact C-N 3.32Å; L394-L396 PolarHBondContact O-N 3.21Å; L396-Q398 PolarHBondContact O-N 2.95Å; L396-I399 HydrophobicContact CD2-CD1 4.15Å; L396-I399 WeakPolarHBondContact O-CB 3.41Å; L396-I399 PolarHBondContact O-N 3.25Å; L396-I399 VanDerWaalsContact O-N 3.11Å; L396-L402 HydrophobicContact CB-CD1 4.46Å; L396-L402 HydrophobicContact CD2-CD1 4.06Å; L396-F406 HydrophobicContact CB-CE2 4.48Å; L396-F406 HydrophobicContact CB-CZ 4.26Å
397	I	86.9	Confident	85.7	Confident	4 Å²	4	28.1 Å²	28.1	2%	0.021	15%	0.146	C	C	.	.	H	α-helix	trans	-64.9	-30.5	179.4	-72.6	167.6	0	0	0	111.3	L393 L394 I399 F406 L413 I446 C449 I450 Y453	L393-I397 HydrophobicContact CD1-CD1 3.7Å; L393-I397 HydrophobicContact CD1-CG1 4.11Å; L393-I397 HydrophobicContact CG-CD1 3.76Å; L393-I397 WeakPolarHBondContact O-CG1 3.49Å; L393-I397 PolarHBondContact O-N 3.39Å; L394-I397 PolarHBondContact O-N 3.08Å; I397-I399 PolarHBondContact O-N 2.93Å; I397-F406 HydrophobicContact CB-CE2 4.47Å; I397-F406 HydrophobicContact CD1-CE1 4.42Å; I397-F406 HydrophobicContact CG1-CD1 4.18Å; I397-F406 HydrophobicContact CG1-CD2 3.98Å; I397-F406 HydrophobicContact CG1-CE1 3.91Å; I397-F406 HydrophobicContact CG1-CE2 3.69Å; I397-F406 HydrophobicContact CG1-CG 4.21Å; I397-F406 HydrophobicContact CG1-CZ 3.66Å; I397-L413 HydrophobicContact CD1-CD2 4.2Å; I397-I446 HydrophobicContact CD1-CG2 3.44Å; I397-I446 VanDerWaalsContact CD1-CG2 3.44Å; I397-C449 HydrophobicContact CG2-CB 3.8Å; I397-I450 HydrophobicContact CD1-CD1 4.08Å; I397-I450 HydrophobicContact CD1-CG1 4Å; I397-I450 HydrophobicContact CG2-CG1 4.24Å; I397-Y453 HydrophobicContact CG2-CD2 4.16Å; I397-Y453 HydrophobicContact CG2-CE2 4.03Å; I397-Y453 WeakPolarHBondContact O-CE2 2.97Å
398	Q	85.6	Confident	84.8	Confident	70 Å²	70	36.4 Å²	36.4	33%	0.327	18%	0.182	S	C	.	.	T	Hydrogen-bonded Turn	trans	-72.5	-13.1	176.9	-72.1	177.6	-11.6	0	0	113.8	L394 N395 L396 P400 Y453	L394-Q398 HydrophobicContact CD1-CG 4.5Å; L394-Q398 VanDerWaalsContact O-CG 3.31Å; L394-Q398 WeakPolarHBondContact O-CG 3.37Å; L394-Q398 PolarHBondContact O-N 3.17Å; N395-Q398 PolarHBondContact O-N 3.35Å; L396-Q398 PolarHBondContact O-N 2.95Å; Q398-P400 VanDerWaalsContact O-CD 3.31Å; Q398-P400 WeakPolarHBondContact O-CD 3.34Å; Q398-Y453 WeakPolarHBondContact CA-OH 3.41Å
399	I	84.8	Confident	84.2	Confident	10 Å²	10	36 Å²	36	5%	0.051	18%	0.18	C	C	.	.			trans	-74.4	118	179.8	-61.6	176.6	0	0	0	109.7	L286 M287 N395 L396 I397 Y401 L402	L286-I399 HydrophobicContact CB-CD1 3.73Å; M287-I399 HydrophobicContact CB-CD1 4.43Å; M287-I399 HydrophobicContact CG-CD1 3.65Å; M287-I399 HydrophobicContact CG-CG1 4.04Å; N395-I399 WeakPolarHBondContact O-CG1 3.31Å; L396-I399 HydrophobicContact CD2-CD1 4.15Å; L396-I399 WeakPolarHBondContact O-CB 3.41Å; L396-I399 PolarHBondContact O-N 3.25Å; L396-I399 VanDerWaalsContact O-N 3.11Å; I397-I399 PolarHBondContact O-N 2.93Å; I399-Y401 VanDerWaalsContact C-N 3.33Å; I399-Y401 HydrophobicContact CG2-CD1 3.44Å; I399-Y401 VanDerWaalsContact CG2-CD1 3.44Å; I399-Y401 HydrophobicContact CG2-CD2 4.19Å; I399-Y401 HydrophobicContact CG2-CE1 3.13Å; I399-Y401 HydrophobicContact CG2-CE2 3.91Å; I399-Y401 HydrophobicContact CG2-CG 3.97Å; I399-Y401 PolarHBondContact O-N 3.41Å; I399-L402 HydrophobicContact CB-CB 4.22Å; I399-L402 HydrophobicContact CB-CD1 4.01Å; I399-L402 HydrophobicContact CB-CG 4.06Å; I399-L402 HydrophobicContact CD1-CD1 3.78Å; I399-L402 HydrophobicContact CG1-CD1 4.41Å; I399-L402 HydrophobicContact CG2-CB 4.35Å; I399-L402 HydrophobicContact CG2-CD1 4.21Å; I399-L402 HydrophobicContact CG2-CG 3.89Å; I399-L402 PolarHBondContact O-N 3.34Å; I399-L402 VanDerWaalsContact O-N 3.1Å
400	P	80.7	Confident	83.8	Confident	93 Å²	93	36.4 Å²	36.4	60%	0.604	18%	0.182	S	C	*	.	G	3₁₀ helix	trans	-59	-37.2	-171.7	-27.4	35.5	0	0	0	115.5	Q398 K403	Q398-P400 VanDerWaalsContact O-CD 3.31Å; Q398-P400 WeakPolarHBondContact O-CD 3.34Å; P400-K403 WeakPolarHBondContact O-CB 3.33Å; P400-K403 VanDerWaalsContact O-CD 3.3Å; P400-K403 WeakPolarHBondContact O-CD 3.41Å; P400-K403 WeakPolarHBondContact O-CG 3.29Å
401	Y	80.5	Confident	83.3	Confident	35 Å²	35	39.7 Å²	39.7	14%	0.137	20%	0.197	C	C	.	.	G	3₁₀ helix	trans	-83.2	-11.4	-177.2	66.7	-100.5	0	0	0	113.3	L286 Q293 L296 I399	L286-Y401 VanDerWaalsContact C-OH 3.25Å; L286-Y401 WeakPolarHBondContact CA-OH 3.12Å; L286-Y401 PolarHBondContact O-OH 2.72Å; Q293-Y401 HydrophobicContact CB-CD1 4.2Å; Q293-Y401 HydrophobicContact CB-CE1 3.78Å; Q293-Y401 HydrophobicContact CG-CD1 3.56Å; Q293-Y401 HydrophobicContact CG-CE1 3.66Å; Q293-Y401 HydrophobicContact CG-CG 4.06Å; L296-Y401 HydrophobicContact CB-CD2 4.19Å; L296-Y401 HydrophobicContact CB-CE2 4.13Å; L296-Y401 HydrophobicContact CD1-CE2 4.01Å; I399-Y401 VanDerWaalsContact C-N 3.33Å; I399-Y401 HydrophobicContact CG2-CD1 3.44Å; I399-Y401 VanDerWaalsContact CG2-CD1 3.44Å; I399-Y401 HydrophobicContact CG2-CD2 4.19Å; I399-Y401 HydrophobicContact CG2-CE1 3.13Å; I399-Y401 HydrophobicContact CG2-CE2 3.91Å; I399-Y401 HydrophobicContact CG2-CG 3.97Å; I399-Y401 PolarHBondContact O-N 3.41Å
402	L	82.9	Confident	82.9	Confident	0 Å²	0	38.3 Å²	38.3	0%	0	19%	0.192	C	C	.	.	G	3₁₀ helix	trans	-86.3	-11.7	173.9	-68.1	-175.3	0	0	0	113.2	L286 L296 F315 L396 I399 V404 Y405 F406	L286-L402 HydrophobicContact CB-CD1 4.45Å; L286-L402 HydrophobicContact CD1-CD1 4.17Å; L286-L402 HydrophobicContact CD2-CD1 4.47Å; L286-L402 HydrophobicContact CD2-CD2 4.46Å; L296-L402 HydrophobicContact CD1-CD2 3.83Å; F315-L402 HydrophobicContact CE1-CD2 4.2Å; F315-L402 HydrophobicContact CZ-CD2 3.81Å; L396-L402 HydrophobicContact CB-CD1 4.46Å; L396-L402 HydrophobicContact CD2-CD1 4.06Å; I399-L402 HydrophobicContact CB-CB 4.22Å; I399-L402 HydrophobicContact CB-CD1 4.01Å; I399-L402 HydrophobicContact CB-CG 4.06Å; I399-L402 HydrophobicContact CD1-CD1 3.78Å; I399-L402 HydrophobicContact CG1-CD1 4.41Å; I399-L402 HydrophobicContact CG2-CB 4.35Å; I399-L402 HydrophobicContact CG2-CD1 4.21Å; I399-L402 HydrophobicContact CG2-CG 3.89Å; I399-L402 PolarHBondContact O-N 3.34Å; I399-L402 VanDerWaalsContact O-N 3.1Å; L402-V404 VanDerWaalsContact C-N 3.27Å; L402-V404 PolarHBondContact O-N 3.38Å; L402-Y405 HydrophobicContact CD2-CD2 3.85Å; L402-Y405 HydrophobicContact CD2-CE2 4.11Å; L402-Y405 WeakPolarHBondContact O-CB 3.28Å; L402-Y405 PolarHBondContact O-N 3.35Å; L402-F406 HydrophobicContact CB-CE2 4.32Å
403	K	76.6	Confident	82.8	Confident	38 Å²	38	38.4 Å²	38.4	17%	0.165	19%	0.193	C	C	.	.	H	α-helix	trans	-50.9	-46.1	-176.5	-70.5	177.3	177.9	-175.7	0	112.9	P400 Y405 F406 I407 Y453	P400-K403 WeakPolarHBondContact O-CB 3.33Å; P400-K403 VanDerWaalsContact O-CD 3.3Å; P400-K403 WeakPolarHBondContact O-CD 3.41Å; P400-K403 WeakPolarHBondContact O-CG 3.29Å; K403-Y405 PolarHBondContact O-N 3.19Å; K403-Y405 VanDerWaalsContact O-N 3.08Å; K403-F406 PolarHBondContact O-N 2.93Å; K403-I407 WeakPolarHBondContact O-CG1 3.44Å; K403-I407 PolarHBondContact O-N 3.22Å; K403-Y453 HydrophobicContact CD-CD1 4.09Å; K403-Y453 HydrophobicContact CD-CG 4.19Å; K403-Y453 HydrophobicContact CG-CG 4.43Å
404	V	74.7	Confident	82.6	Confident	96 Å²	96	38.4 Å²	38.4	58%	0.582	19%	0.193	S	C	*	.	H	α-helix	trans	-54.7	-32.8	-178.5	-178.1	0	0	0	0	112	L402	L402-V404 VanDerWaalsContact C-N 3.27Å; L402-V404 PolarHBondContact O-N 3.38Å
405	Y	78.6	Confident	82.4	Confident	31 Å²	31	38.3 Å²	38.3	12%	0.122	19%	0.192	C	C	.	.	H	α-helix	trans	-78	-27.5	-177.7	-56.6	-56.4	0	0	0	113.5	L296 M312 L316 L402 K403	L296-Y405 HydrophobicContact CB-CE2 4.42Å; L296-Y405 PolarHBondContact O-OH 3.12Å; M312-Y405 VanDerWaalsContact CE-OH 3.31Å; M312-Y405 WeakPolarHBondContact CE-OH 3.31Å; L316-Y405 HydrophobicContact CD2-CD1 3.17Å; L316-Y405 HydrophobicContact CD2-CE1 3.41Å; L316-Y405 VanDerWaalsContact CD2-CE1 3.41Å; L316-Y405 HydrophobicContact CD2-CG 3.8Å; L402-Y405 HydrophobicContact CD2-CD2 3.85Å; L402-Y405 HydrophobicContact CD2-CE2 4.11Å; L402-Y405 WeakPolarHBondContact O-CB 3.28Å; L402-Y405 PolarHBondContact O-N 3.35Å; K403-Y405 PolarHBondContact O-N 3.19Å; K403-Y405 VanDerWaalsContact O-N 3.08Å
406	F	78.3	Confident	82.3	Confident	6 Å²	6	36.1 Å²	36.1	3%	0.026	18%	0.18	C	C	.	.	H	α-helix	trans	-81	-25.9	175.5	-70.9	-71.3	0	0	0	112.5	I319 L393 L396 I397 L402 K403 K408 T409 N410 L413	I319-F406 HydrophobicContact CG2-CD1 4.39Å; I319-F406 HydrophobicContact CG2-CE1 3.85Å; I319-F406 HydrophobicContact CG2-CE2 4.15Å; I319-F406 HydrophobicContact CG2-CZ 3.72Å; L393-F406 HydrophobicContact CD1-CE1 3.92Å; L393-F406 HydrophobicContact CD1-CZ 4.12Å; L396-F406 HydrophobicContact CB-CE2 4.48Å; L396-F406 HydrophobicContact CB-CZ 4.26Å; I397-F406 HydrophobicContact CB-CE2 4.47Å; I397-F406 HydrophobicContact CD1-CE1 4.42Å; I397-F406 HydrophobicContact CG1-CD1 4.18Å; I397-F406 HydrophobicContact CG1-CD2 3.98Å; I397-F406 HydrophobicContact CG1-CE1 3.91Å; I397-F406 HydrophobicContact CG1-CE2 3.69Å; I397-F406 HydrophobicContact CG1-CG 4.21Å; I397-F406 HydrophobicContact CG1-CZ 3.66Å; L402-F406 HydrophobicContact CB-CE2 4.32Å; K403-F406 PolarHBondContact O-N 2.93Å; F406-K408 PolarHBondContact O-N 3.32Å; F406-K408 VanDerWaalsContact O-N 3.07Å; F406-T409 CarbonylContact O-C 3.44Å; F406-T409 PolarHBondContact O-N 3.47Å; F406-T409 PolarHBondContact O-OG1 3.46Å; F406-N410 WeakPolarHBondContact CB-OD1 3.07Å; F406-N410 PolarHBondContact O-N 3.35Å; F406-N410 PolarHBondContact O-OD1 3.36Å; F406-L413 HydrophobicContact CD1-CD2 4.15Å; F406-L413 HydrophobicContact CE1-CD2 4.42Å
407	I	72.1	Confident	82.4	Confident	77 Å²	77	36.1 Å²	36.1	40%	0.395	18%	0.18	S	C	.	.	H	α-helix	trans	-48.3	-44.6	-177.7	-66.8	175.1	0	0	0	112.5	K403 T409	K403-I407 WeakPolarHBondContact O-CG1 3.44Å; K403-I407 PolarHBondContact O-N 3.22Å; I407-T409 VanDerWaalsContact C-N 3.29Å; I407-T409 PolarHBondContact O-N 2.91Å
408	K	70.1	Confident	82.6	Confident	175 Å²	175	36 Å²	36	76%	0.761	18%	0.18	S	C	*	.	T	Hydrogen-bonded Turn	trans	-66.6	-27.8	-178.5	-68.8	-169.9	176.3	-172.2	0	113.9	F406	F406-K408 PolarHBondContact O-N 3.32Å; F406-K408 VanDerWaalsContact O-N 3.07Å
409	T	78.7	Confident	82.7	Confident	6 Å²	6	32.7 Å²	32.7	4%	0.037	16%	0.164	C	C	.	.	T	Hydrogen-bonded Turn	trans	-113.8	-1.3	-172.6	59.6	0	0	0	0	113.5	Q320 Y321 F406 I407 F411 N412 L413	Q320-T409 HydrophobicContact CB-CG2 3.93Å; Q320-T409 HydrophobicContact CG-CG2 4.34Å; Y321-T409 HydrophobicContact CE1-CG2 4.39Å; F406-T409 CarbonylContact O-C 3.44Å; F406-T409 PolarHBondContact O-N 3.47Å; F406-T409 PolarHBondContact O-OG1 3.46Å; I407-T409 VanDerWaalsContact C-N 3.29Å; I407-T409 PolarHBondContact O-N 2.91Å; T409-F411 VanDerWaalsContact C-N 3.33Å; T409-F411 PolarHBondContact O-N 2.91Å; T409-N412 PolarHBondContact O-N 3.03Å; T409-N412 VanDerWaalsContact O-N 3.15Å; T409-L413 VanDerWaalsContact O-CB 3.32Å; T409-L413 WeakPolarHBondContact O-CB 3.41Å; T409-L413 PolarHBondContact O-N 2.92Å
410	N	83.9	Confident	82.9	Confident	9 Å²	9	32.2 Å²	32.2	5%	0.048	16%	0.162	C	C	.	.	H	α-helix	trans	-46.9	-51.2	-176.5	-81.5	-12.5	0	0	0	113.3	F406 L413 I414 I450	F406-N410 WeakPolarHBondContact CB-OD1 3.07Å; F406-N410 PolarHBondContact O-N 3.35Å; F406-N410 PolarHBondContact O-OD1 3.36Å; N410-L413 PolarHBondContact O-N 3.15Å; N410-I414 VanDerWaalsContact O-CG1 3.24Å; N410-I414 WeakPolarHBondContact O-CG1 3.49Å; N410-I414 PolarHBondContact O-N 3.25Å; N410-I450 HydrophobicContact CB-CG2 3.73Å; N410-I450 VanDerWaalsContact CG-CG2 3.46Å; N410-I450 WeakPolarHBondContact OD1-CG2 3.07Å
411	F	83.9	Confident	83.3	Confident	70 Å²	70	27.8 Å²	27.8	31%	0.307	13%	0.133	S	C	.	.	H	α-helix	trans	-63.5	-49.3	-178.1	-177.6	-106.6	0	0	0	112.1	F349 T409 L413 I414 Q415 I491 L495 F531	F349-F411 HydrophobicContact CE1-CE1 4.01Å; T409-F411 VanDerWaalsContact C-N 3.33Å; T409-F411 PolarHBondContact O-N 2.91Å; F411-L413 VanDerWaalsContact C-N 3.31Å; F411-L413 PolarHBondContact O-N 3.21Å; F411-I414 PolarHBondContact O-N 3.43Å; F411-Q415 WeakPolarHBondContact O-CG 3.48Å; F411-Q415 PolarHBondContact O-N 3.44Å; F411-Q415 VanDerWaalsContact O-N 3.11Å; F411-I491 HydrophobicContact CE2-CG2 4.48Å; F411-I491 HydrophobicContact CZ-CG2 3.97Å; F411-L495 HydrophobicContact CE2-CD1 3.93Å; F411-L495 HydrophobicContact CZ-CD1 4.45Å; F411-F531 AromaticContact CD2-CE1 4Å; F411-F531 HydrophobicContact CD2-CE1 4Å; F411-F531 HydrophobicContact CD2-CZ 4.32Å; F411-F531 AromaticContact CE2-CE1 3.92Å; F411-F531 HydrophobicContact CE2-CE1 3.92Å; F411-F531 HydrophobicContact CE2-CZ 4.44Å
412	N	85.7	Confident	83.3	Confident	34 Å²	34	26.9 Å²	26.9	18%	0.182	13%	0.13	C	C	.	.	H	α-helix	trans	-63.9	-38	178	-67.2	-10.1	0	0	0	111.4	F250 M324 T409 Q415 C416	F250-N412 HydrophobicContact CE1-CB 4Å; F250-N412 HydrophobicContact CE2-CB 4.25Å; F250-N412 HydrophobicContact CZ-CB 3.66Å; M324-N412 HydrophobicContact SD-CB 3.49Å; M324-N412 WeakPolarHBondContact SD-CB 3.4Å; T409-N412 PolarHBondContact O-N 3.03Å; T409-N412 VanDerWaalsContact O-N 3.15Å; N412-Q415 PolarHBondContact O-N 3.35Å; N412-C416 PolarHBondContact O-N 3.02Å; N412-C416 PolarHBondContact O-SG 3.35Å
413	L	89	Confident	83.2	Confident	4 Å²	4	26.9 Å²	26.9	2%	0.021	13%	0.13	C	C	.	.	H	α-helix	trans	-64.8	-44.1	176.9	-177.7	58.9	0	0	0	111.4	L393 I397 F406 T409 N410 F411 Q415 C416 L417 I450	L393-L413 HydrophobicContact CD2-CD1 4.19Å; I397-L413 HydrophobicContact CD1-CD2 4.2Å; F406-L413 HydrophobicContact CD1-CD2 4.15Å; F406-L413 HydrophobicContact CE1-CD2 4.42Å; T409-L413 VanDerWaalsContact O-CB 3.32Å; T409-L413 WeakPolarHBondContact O-CB 3.41Å; T409-L413 PolarHBondContact O-N 2.92Å; N410-L413 PolarHBondContact O-N 3.15Å; F411-L413 VanDerWaalsContact C-N 3.31Å; F411-L413 PolarHBondContact O-N 3.21Å; L413-Q415 VanDerWaalsContact C-N 3.29Å; L413-Q415 PolarHBondContact O-N 3.42Å; L413-C416 PolarHBondContact O-N 3.14Å; L413-L417 HydrophobicContact CD1-CD1 4.19Å; L413-L417 HydrophobicContact CD1-CG 4.2Å; L413-L417 HydrophobicContact CG-CD1 3.95Å; L413-L417 HydrophobicContact CG-CG 4.42Å; L413-L417 WeakPolarHBondContact O-CB 3.4Å; L413-L417 WeakPolarHBondContact O-CG 3.37Å; L413-L417 PolarHBondContact O-N 3.2Å; L413-I450 HydrophobicContact CD2-CD1 3.67Å; L413-I450 HydrophobicContact CG-CD1 4.03Å
414	I	88.7	Confident	83.4	Confident	0 Å²	0	25.1 Å²	25.1	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-56.5	-45.9	174.2	-71.1	164.9	0	0	0	110.2	N410 F411 L417 L418 I450 F527 Y530 F531	N410-I414 VanDerWaalsContact O-CG1 3.24Å; N410-I414 WeakPolarHBondContact O-CG1 3.49Å; N410-I414 PolarHBondContact O-N 3.25Å; F411-I414 PolarHBondContact O-N 3.43Å; I414-L417 PolarHBondContact O-N 3.23Å; I414-L418 HydrophobicContact CG2-CD1 3.9Å; I414-L418 HydrophobicContact CG2-CG 4.38Å; I414-L418 WeakPolarHBondContact O-CB 3.28Å; I414-L418 WeakPolarHBondContact O-CG 3.37Å; I414-L418 PolarHBondContact O-N 3.5Å; I414-I450 HydrophobicContact CD1-CG2 3.91Å; I414-I450 HydrophobicContact CG1-CD1 4.32Å; I414-I450 HydrophobicContact CG1-CG2 4.2Å; I414-F527 HydrophobicContact CG2-CE2 4.35Å; I414-Y530 HydrophobicContact CD1-CE1 4.17Å; I414-F531 HydrophobicContact CD1-CE2 4.37Å; I414-F531 HydrophobicContact CD1-CZ 4.22Å; I414-F531 HydrophobicContact CG2-CZ 4.46Å
415	Q	87.3	Confident	83.4	Confident	1 Å²	1	21.1 Å²	21.1	1%	0.005	10%	0.097	C	C	.	.	H	α-helix	trans	-64.2	-42.5	178.1	-68.6	-179	-19	0	0	112.9	L352 F411 N412 L413 L417 L418 Y419 L495	L352-Q415 HydrophobicContact CD1-CB 4.05Å; L352-Q415 HydrophobicContact CD1-CG 4.31Å; F411-Q415 WeakPolarHBondContact O-CG 3.48Å; F411-Q415 PolarHBondContact O-N 3.44Å; F411-Q415 VanDerWaalsContact O-N 3.11Å; N412-Q415 PolarHBondContact O-N 3.35Å; L413-Q415 VanDerWaalsContact C-N 3.29Å; L413-Q415 PolarHBondContact O-N 3.42Å; Q415-L417 VanDerWaalsContact C-N 3.3Å; Q415-L417 PolarHBondContact O-N 2.98Å; Q415-L418 PolarHBondContact O-N 2.76Å; Q415-Y419 VanDerWaalsContact O-CB 3.26Å; Q415-Y419 WeakPolarHBondContact O-CB 3.33Å; Q415-Y419 PolarHBondContact O-N 2.66Å; Q415-L495 HydrophobicContact CG-CD2 4.02Å
416	C	90.2	Very high	82.8	Confident	0 Å²	0	22 Å²	22	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-62.9	-38.9	176.8	-68.9	0	0	0	0	112	F250 M324 C327 L328 N412 L413 L420	F250-C416 WeakPolarHBondContact CZ-SG 3.46Å; M324-C416 HydrophobicContact CG-CB 4.04Å; M324-C416 WeakPolarHBondContact CG-SG 3.24Å; C327-C416 HydrophobicContact CB-CB 4.11Å; L328-C416 HydrophobicContact CD2-CB 4.16Å; L328-C416 WeakPolarHBondContact CD2-SG 3.32Å; L328-C416 HydrophobicContact CG-CB 4.32Å; L328-C416 WeakPolarHBondContact CG-SG 2.82Å; N412-C416 PolarHBondContact O-N 3.02Å; N412-C416 PolarHBondContact O-SG 3.35Å; L413-C416 PolarHBondContact O-N 3.14Å; C416-L420 VanDerWaalsContact O-CB 3.3Å; C416-L420 WeakPolarHBondContact O-CB 2.99Å; C416-L420 PolarHBondContact O-N 3.44Å
417	L	92.4	Very high	82	Confident	0 Å²	0	22.4 Å²	22.4	0%	0	10%	0.104	C	C	.	.	H	α-helix	trans	-69.9	-43.4	177.4	-71.5	169	0	0	0	111.7	L390 L393 L413 I414 Q415 Y419 L420 A421 I443 I446 I447 I450	L390-L417 HydrophobicContact CD2-CD2 3.69Å; L393-L417 HydrophobicContact CD2-CD2 4.32Å; L413-L417 HydrophobicContact CD1-CD1 4.19Å; L413-L417 HydrophobicContact CD1-CG 4.2Å; L413-L417 HydrophobicContact CG-CD1 3.95Å; L413-L417 HydrophobicContact CG-CG 4.42Å; L413-L417 WeakPolarHBondContact O-CB 3.4Å; L413-L417 WeakPolarHBondContact O-CG 3.37Å; L413-L417 PolarHBondContact O-N 3.2Å; I414-L417 PolarHBondContact O-N 3.23Å; Q415-L417 VanDerWaalsContact C-N 3.3Å; Q415-L417 PolarHBondContact O-N 2.98Å; L417-Y419 VanDerWaalsContact C-N 3.33Å; L417-L420 PolarHBondContact O-N 3.27Å; L417-A421 VanDerWaalsContact O-CB 3.24Å; L417-A421 WeakPolarHBondContact O-CB 3.44Å; L417-A421 PolarHBondContact O-N 3.22Å; L417-I443 HydrophobicContact CB-CG2 3.93Å; L417-I443 HydrophobicContact CD2-CG1 4.14Å; L417-I446 HydrophobicContact CD1-CB 4.14Å; L417-I446 HydrophobicContact CD1-CG2 3.37Å; L417-I447 HydrophobicContact CB-CD1 4.2Å; L417-I447 HydrophobicContact CB-CG1 4.29Å; L417-I447 HydrophobicContact CD1-CG1 4.05Å; L417-I450 HydrophobicContact CD1-CD1 4.32Å
418	L	89.6	Confident	81.4	Confident	1 Å²	1	19.2 Å²	19.2	1%	0.005	9%	0.088	C	C	.	.	H	α-helix	trans	-63.3	-40.9	174.2	-72.7	174.2	0	0	0	111.3	L352 I414 Q415 A421 K422 I447 L495 N498 F499 L502	L352-L418 HydrophobicContact CD2-CB 4.23Å; I414-L418 HydrophobicContact CG2-CD1 3.9Å; I414-L418 HydrophobicContact CG2-CG 4.38Å; I414-L418 WeakPolarHBondContact O-CB 3.28Å; I414-L418 WeakPolarHBondContact O-CG 3.37Å; I414-L418 PolarHBondContact O-N 3.5Å; Q415-L418 PolarHBondContact O-N 2.76Å; L418-A421 PolarHBondContact O-N 3.47Å; L418-K422 VanDerWaalsContact O-CB 3.3Å; L418-K422 WeakPolarHBondContact O-CB 3.12Å; L418-K422 PolarHBondContact O-N 3.36Å; L418-I447 HydrophobicContact CD2-CD1 3.81Å; L418-I447 HydrophobicContact CG-CD1 3.99Å; L418-L495 HydrophobicContact CD1-CB 4.09Å; L418-L495 HydrophobicContact CD1-CD2 3.57Å; L418-L495 HydrophobicContact CD1-CG 4.4Å; L418-N498 HydrophobicContact CD2-CB 4.45Å; L418-F499 HydrophobicContact CD2-CB 4.23Å; L418-F499 HydrophobicContact CD2-CD2 4.03Å; L418-L502 HydrophobicContact CD2-CD1 3.53Å
419	Y	88	Confident	80.6	Confident	0 Å²	0	15.5 Å²	15.5	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-61.6	-49.2	173.3	166.2	-104.3	0	0	0	112.1	L256 L328 K332 L335 L343 L348 F351 Q415 L417 A421 K422 C423	L256-Y419 HydrophobicContact CD1-CE2 4.46Å; L256-Y419 HydrophobicContact CD2-CE1 4.23Å; L328-Y419 HydrophobicContact CD2-CD1 3.92Å; L328-Y419 HydrophobicContact CD2-CE1 4.24Å; K332-Y419 VanDerWaalsContact CA-OH 3.24Å; K332-Y419 WeakPolarHBondContact CA-OH 3.46Å; K332-Y419 PolarHBondContact N-OH 2.84Å; L335-Y419 HydrophobicContact CD1-CE2 4.45Å; L335-Y419 VanDerWaalsContact CD1-OH 3.25Å; L335-Y419 WeakPolarHBondContact CD1-OH 3.19Å; L335-Y419 HydrophobicContact CD2-CE2 4.09Å; L335-Y419 HydrophobicContact CG-CE2 4.42Å; L343-Y419 HydrophobicContact CD1-CE2 3.98Å; L348-Y419 HydrophobicContact CD1-CD1 4.28Å; L348-Y419 HydrophobicContact CD1-CD2 3.25Å; L348-Y419 HydrophobicContact CD1-CE2 3.8Å; L348-Y419 HydrophobicContact CD1-CG 3.51Å; F351-Y419 HydrophobicContact CD1-CD2 4.04Å; F351-Y419 HydrophobicContact CD1-CE2 4.38Å; F351-Y419 AromaticContact CE1-CD2 3.87Å; F351-Y419 HydrophobicContact CE1-CD2 3.87Å; F351-Y419 HydrophobicContact CE1-CE2 4.12Å; Q415-Y419 VanDerWaalsContact O-CB 3.26Å; Q415-Y419 WeakPolarHBondContact O-CB 3.33Å; Q415-Y419 PolarHBondContact O-N 2.66Å; L417-Y419 VanDerWaalsContact C-N 3.33Å; Y419-A421 VanDerWaalsContact C-N 3.27Å; Y419-A421 PolarHBondContact O-N 3.12Å; Y419-K422 PolarHBondContact O-N 3.05Å; Y419-C423 WeakPolarHBondContact CE2-SG 3.42Å; Y419-C423 VanDerWaalsContact CZ-SG 3.59Å; Y419-C423 PolarHBondContact O-N 3.24Å; Y419-C423 PolarHBondContact O-SG 3.4Å
420	L	90.1	Very high	79.7	Confident	0 Å²	0	17 Å²	17	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-58.4	-43.4	176.6	177.6	63	0	0	0	110.8	C327 I330 W334 T386 L390 C416 L417 C423 L424 I443	C327-L420 HydrophobicContact CB-CD2 4.13Å; I330-L420 HydrophobicContact CB-CD1 4.03Å; I330-L420 HydrophobicContact CG2-CD1 3.67Å; W334-L420 HydrophobicContact CE3-CD1 3.95Å; W334-L420 HydrophobicContact CZ3-CD1 3.66Å; T386-L420 HydrophobicContact CG2-CD2 4.12Å; L390-L420 HydrophobicContact CD2-CD2 4.3Å; C416-L420 VanDerWaalsContact O-CB 3.3Å; C416-L420 WeakPolarHBondContact O-CB 2.99Å; C416-L420 PolarHBondContact O-N 3.44Å; L417-L420 PolarHBondContact O-N 3.27Å; L420-C423 PolarHBondContact O-N 3.35Å; L420-L424 HydrophobicContact CD1-CD1 4.46Å; L420-L424 HydrophobicContact CG-CD1 4.16Å; L420-L424 WeakPolarHBondContact O-CB 3.1Å; L420-L424 WeakPolarHBondContact O-CG 3.13Å; L420-L424 PolarHBondContact O-N 2.9Å; L420-I443 HydrophobicContact CD2-CD1 4.15Å; L420-I443 HydrophobicContact CG-CD1 4.19Å
421	A	87.4	Confident	78.5	Confident	0 Å²	0	23.7 Å²	23.7	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-66.1	-41.1	177.9	0	0	0	0	0	111.8	L417 L418 Y419 C423 L424 F425 I443 L502	L417-A421 VanDerWaalsContact O-CB 3.24Å; L417-A421 WeakPolarHBondContact O-CB 3.44Å; L417-A421 PolarHBondContact O-N 3.22Å; L418-A421 PolarHBondContact O-N 3.47Å; Y419-A421 VanDerWaalsContact C-N 3.27Å; Y419-A421 PolarHBondContact O-N 3.12Å; A421-C423 VanDerWaalsContact C-N 3.33Å; A421-C423 PolarHBondContact O-N 3.11Å; A421-L424 PolarHBondContact O-N 3.47Å; A421-F425 WeakPolarHBondContact O-CB 3.42Å; A421-F425 PolarHBondContact O-N 3.01Å; A421-I443 HydrophobicContact CB-CD1 3.74Å; A421-I443 HydrophobicContact CB-CG2 4.02Å; A421-L502 HydrophobicContact CB-CD1 3.46Å; A421-L502 VanDerWaalsContact CB-CD1 3.46Å; A421-L502 HydrophobicContact CB-CD2 3.44Å; A421-L502 VanDerWaalsContact CB-CD2 3.44Å; A421-L502 HydrophobicContact CB-CG 4.09Å
422	K	81.2	Confident	77.9	Confident	17 Å²	17	22.9 Å²	22.9	7%	0.074	12%	0.119	C	C	.	.	H	α-helix	trans	-60.7	-42.4	172.6	-163.6	169.8	-176.4	169.7	0	110.2	F351 L352 L418 Y419 F425 Y426	F351-K422 HydrophobicContact CD1-CD 4.42Å; F351-K422 HydrophobicContact CE1-CD 3.74Å; F351-K422 HydrophobicContact CE1-CG 4.32Å; F351-K422 HydrophobicContact CZ-CD 4.1Å; F351-K422 PolarHBondContact O-NZ 3Å; L352-K422 HydrophobicContact CD2-CD 4.21Å; L418-K422 VanDerWaalsContact O-CB 3.3Å; L418-K422 WeakPolarHBondContact O-CB 3.12Å; L418-K422 PolarHBondContact O-N 3.36Å; Y419-K422 PolarHBondContact O-N 3.05Å; K422-F425 PolarHBondContact O-N 3.28Å; K422-Y426 HydrophobicContact CB-CD2 4.28Å; K422-Y426 HydrophobicContact CD-CD2 4.47Å; K422-Y426 HydrophobicContact CD-CE2 4.35Å; K422-Y426 HydrophobicContact CG-CD2 3.37Å; K422-Y426 HydrophobicContact CG-CE2 3.58Å; K422-Y426 HydrophobicContact CG-CG 4.43Å; K422-Y426 VanDerWaalsContact O-CB 3.32Å; K422-Y426 WeakPolarHBondContact O-CB 3.44Å; K422-Y426 VanDerWaalsContact O-CD2 3.3Å; K422-Y426 WeakPolarHBondContact O-CD2 3.37Å; K422-Y426 PolarHBondContact O-N 3.26Å
423	C	81.3	Confident	77.2	Confident	0 Å²	0	24.2 Å²	24.2	0%	0	13%	0.131	C	C	.	.	I	π-helix	trans	-66.8	-46.7	176.5	-63.3	0	0	0	0	112.3	G331 W334 L335 Y419 L420 A421 F425 C427 S428	G331-C423 PolarHBondContact O-SG 3.26Å; G331-C423 VanDerWaalsContact O-SG 3.38Å; W334-C423 HydrophobicContact CB-CB 4.24Å; L335-C423 VanDerWaalsContact CD2-SG 3.54Å; Y419-C423 WeakPolarHBondContact CE2-SG 3.42Å; Y419-C423 VanDerWaalsContact CZ-SG 3.59Å; Y419-C423 PolarHBondContact O-N 3.24Å; Y419-C423 PolarHBondContact O-SG 3.4Å; L420-C423 PolarHBondContact O-N 3.35Å; A421-C423 VanDerWaalsContact C-N 3.33Å; A421-C423 PolarHBondContact O-N 3.11Å; C423-F425 VanDerWaalsContact C-N 3.27Å; C423-F425 PolarHBondContact O-N 2.71Å; C423-C427 WeakPolarHBondContact O-CA 3.44Å; C423-C427 VanDerWaalsContact O-CB 3.24Å; C423-C427 WeakPolarHBondContact O-CB 3.44Å; C423-C427 PolarHBondContact O-N 3.32Å; C423-S428 PolarHBondContact O-N 3.27Å
424	L	80.6	Confident	76.7	Confident	0 Å²	0	27.5 Å²	27.5	0%	0	15%	0.148	C	C	.	.	I	π-helix	trans	-59.3	-38.9	173.6	-83.4	171.3	0	0	0	112.1	W334 L383 L420 A421 S428 C439 I443	W334-L424 HydrophobicContact CD2-CD2 4.16Å; W334-L424 HydrophobicContact CE3-CD2 3.46Å; W334-L424 VanDerWaalsContact CE3-CD2 3.46Å; W334-L424 HydrophobicContact CE3-CG 3.63Å; W334-L424 HydrophobicContact CH2-CD2 3.46Å; W334-L424 VanDerWaalsContact CH2-CD2 3.46Å; W334-L424 HydrophobicContact CH2-CG 4.19Å; W334-L424 HydrophobicContact CZ2-CD2 4.17Å; W334-L424 HydrophobicContact CZ3-CD1 3.9Å; W334-L424 HydrophobicContact CZ3-CD2 3.06Å; W334-L424 HydrophobicContact CZ3-CG 3.33Å; L383-L424 HydrophobicContact CD1-CD2 3.99Å; L420-L424 HydrophobicContact CD1-CD1 4.46Å; L420-L424 HydrophobicContact CG-CD1 4.16Å; L420-L424 WeakPolarHBondContact O-CB 3.1Å; L420-L424 WeakPolarHBondContact O-CG 3.13Å; L420-L424 PolarHBondContact O-N 2.9Å; A421-L424 PolarHBondContact O-N 3.47Å; L424-S428 WeakPolarHBondContact O-CB 3.34Å; L424-S428 PolarHBondContact O-OG 3.46Å; L424-C439 HydrophobicContact CD1-CB 3.85Å; L424-I443 HydrophobicContact CD1-CD1 4.18Å
425	F	73.6	Confident	76.3	Confident	12 Å²	12	27.5 Å²	27.5	5%	0.053	15%	0.148	C	C	.	.	I	π-helix	trans	-79.6	-56.3	-177.5	173.3	-123.9	0	0	0	111.7	L363 K366 A421 K422 C423 I440 I501 L502 W505	L363-F425 HydrophobicContact CD2-CZ 4.14Å; K366-F425 WeakPolarHBondContact CE-O 3.4Å; K366-F425 PolarHBondContact NZ-O 2.87Å; A421-F425 WeakPolarHBondContact O-CB 3.42Å; A421-F425 PolarHBondContact O-N 3.01Å; K422-F425 PolarHBondContact O-N 3.28Å; C423-F425 VanDerWaalsContact C-N 3.27Å; C423-F425 PolarHBondContact O-N 2.71Å; F425-I440 HydrophobicContact CB-CD1 4.37Å; F425-I501 HydrophobicContact CD1-CG2 4.25Å; F425-I501 HydrophobicContact CE1-CG2 3.83Å; F425-L502 HydrophobicContact CB-CD2 4.49Å; F425-W505 HydrophobicContact CD2-CB 4.21Å; F425-W505 AromaticContact CD2-CD1 3.34Å; F425-W505 AromaticContact CD2-CD2 3.7Å; F425-W505 HydrophobicContact CD2-CD2 3.7Å; F425-W505 AromaticContact CD2-CE2 3.65Å; F425-W505 AromaticContact CD2-CG 3.42Å; F425-W505 HydrophobicContact CD2-CG 3.42Å; F425-W505 VanDerWaalsContact CD2-CG 3.42Å; F425-W505 AromaticContact CD2-NE1 3.36Å; F425-W505 HydrophobicContact CE2-CB 4.02Å; F425-W505 AromaticContact CE2-CD1 2.88Å; F425-W505 HydrophobicContact CE2-CD2 4.07Å; F425-W505 AromaticContact CE2-CE2 3.98Å; F425-W505 AromaticContact CE2-CG 3.36Å; F425-W505 HydrophobicContact CE2-CG 3.36Å; F425-W505 AromaticContact CE2-NE1 3.2Å; F425-W505 HydrophobicContact CG-CG 4.3Å; F425-W505 HydrophobicContact CZ-CB 4.27Å; F425-W505 AromaticContact CZ-CD1 3.73Å; F425-W505 HydrophobicContact CZ-CG 4.08Å
426	Y	66.4	Low	76	Confident	50 Å²	50	27.7 Å²	27.7	20%	0.196	15%	0.149	C	C	.	.	I	π-helix	trans	-78.9	-34.2	-173.6	-75.1	-88.6	0	0	0	113.7	I358 K422	I358-Y426 VanDerWaalsContact CD1-OH 3.27Å; I358-Y426 WeakPolarHBondContact CD1-OH 3.49Å; I358-Y426 HydrophobicContact CG1-CE1 4.49Å; I358-Y426 VanDerWaalsContact CG1-OH 3.24Å; I358-Y426 WeakPolarHBondContact CG1-OH 3.42Å; K422-Y426 HydrophobicContact CB-CD2 4.28Å; K422-Y426 HydrophobicContact CD-CD2 4.47Å; K422-Y426 HydrophobicContact CD-CE2 4.35Å; K422-Y426 HydrophobicContact CG-CD2 3.37Å; K422-Y426 HydrophobicContact CG-CE2 3.58Å; K422-Y426 HydrophobicContact CG-CG 4.43Å; K422-Y426 VanDerWaalsContact O-CB 3.32Å; K422-Y426 WeakPolarHBondContact O-CB 3.44Å; K422-Y426 VanDerWaalsContact O-CD2 3.3Å; K422-Y426 WeakPolarHBondContact O-CD2 3.37Å; K422-Y426 PolarHBondContact O-N 3.26Å
427	C	62	Low	75.5	Confident	15 Å²	15	27.8 Å²	27.8	10%	0.101	15%	0.15	C	C	.	.	I	π-helix	trans	-108.5	-14.5	-164.3	-52.4	0	0	0	0	113.9	W334 C336 C339 C423 N429	W334-C427 WeakPolarHBondContact O-CB 3.27Å; C336-C427 HydrophobicContact CB-CB 3.88Å; C336-C427 PolarHBondContact N-SG 3.11Å; C339-C427 VanDerWaalsContact SG-SG 3.67Å; C423-C427 WeakPolarHBondContact O-CA 3.44Å; C423-C427 VanDerWaalsContact O-CB 3.24Å; C423-C427 WeakPolarHBondContact O-CB 3.44Å; C423-C427 PolarHBondContact O-N 3.32Å; C427-N429 PolarHBondContact O-N 2.89Å
428	S	58.9	Low	75.2	Confident	9 Å²	9	30.8 Å²	30.8	6%	0.063	16%	0.164	C	C	.	.			trans	-74.5	110.8	180	87.9	0	0	0	0	111.1	C423 L424 L430	C423-S428 PolarHBondContact O-N 3.27Å; L424-S428 WeakPolarHBondContact O-CB 3.34Å; L424-S428 PolarHBondContact O-OG 3.46Å; S428-L430 PolarHBondContact O-N 3.21Å; S428-L430 VanDerWaalsContact O-N 3.16Å
429	N	54.8	Low	75.1	Confident	98 Å²	98	30.7 Å²	30.7	52%	0.524	16%	0.164	S	C	.	.			trans	-76.7	22.8	161.7	-74.6	-9.3	0	0	0	111.9	N371 C427	N371-N429 PolarHBondContact O-ND2 3.38Å; C427-N429 PolarHBondContact O-N 2.89Å
430	L	58.1	Low	75.1	Confident	37 Å²	37	30.7 Å²	30.7	19%	0.194	16%	0.164	C	C	.	.			trans	-82.4	131.2	-168.4	-64.4	173.6	0	0	0	110.9	T379 L383 S428 D432 I436	T379-L430 HydrophobicContact CG2-CD2 4.39Å; L383-L430 HydrophobicContact CD2-CD1 4.18Å; S428-L430 PolarHBondContact O-N 3.21Å; S428-L430 VanDerWaalsContact O-N 3.16Å; L430-D432 VanDerWaalsContact C-N 3.25Å; L430-D432 PolarHBondContact O-N 3.27Å; L430-I436 HydrophobicContact CB-CD1 3.66Å; L430-I436 HydrophobicContact CD1-CD1 4.47Å
431	N	58.4	Low	75	Confident	149 Å²	149	32.4 Å²	32.4	80%	0.797	17%	0.171	S	C	*	.	S	Bend	trans	-74.4	-13.6	179.4	-70.4	-22.1	0	0	0	113.1	S433	N431-S433 VanDerWaalsContact C-N 3.31Å; N431-S433 PolarHBondContact O-N 3.32Å
432	D	72.3	Confident	75.1	Confident	53 Å²	53	34.5 Å²	34.5	28%	0.283	18%	0.179	S	C	.	.			trans	-86.8	63.1	-174.7	-65.1	-56.4	0	0	0	113.4	Y380 L383 L430 L434 I435 I436	Y380-D432 VanDerWaalsContact CD2-OD2 3.26Å; Y380-D432 WeakPolarHBondContact CD2-OD2 3.38Å; L383-D432 HydrophobicContact CD2-CB 3.94Å; L430-D432 VanDerWaalsContact C-N 3.25Å; L430-D432 PolarHBondContact O-N 3.27Å; D432-L434 PolarHBondContact O-N 3.01Å; D432-I435 HydrophobicContact CB-CD1 4.28Å; D432-I435 PolarHBondContact O-N 3.37Å; D432-I435 VanDerWaalsContact O-N 3.11Å; D432-I436 WeakPolarHBondContact O-CD1 3.49Å; D432-I436 WeakPolarHBondContact O-CG1 3.44Å; D432-I436 PolarHBondContact O-N 2.97Å
433	S	71.9	Confident	75.7	Confident	62 Å²	62	33.7 Å²	33.7	43%	0.434	18%	0.176	S	C	.	.	H	α-helix	trans	-50.7	-29.7	176.5	60.7	0	0	0	0	113.7	N431 S437	N431-S433 VanDerWaalsContact C-N 3.31Å; N431-S433 PolarHBondContact O-N 3.32Å; S433-S437 VanDerWaalsContact O-CB 3.29Å; S433-S437 WeakPolarHBondContact O-CB 3.33Å; S433-S437 PolarHBondContact O-N 3.28Å; S433-S437 PolarHBondContact O-OG 3.38Å
434	L	76.8	Confident	76.1	Confident	73 Å²	73	33.7 Å²	33.7	38%	0.382	18%	0.176	S	C	.	.	H	α-helix	trans	-64.6	-49	178.8	-169.6	106.6	0	0	0	112.4	D432 S437 Q438 R510	D432-L434 PolarHBondContact O-N 3.01Å; L434-S437 PolarHBondContact O-OG 3.09Å; L434-Q438 WeakPolarHBondContact O-CG 3.19Å; L434-Q438 PolarHBondContact O-N 3.39Å; L434-R510 VanDerWaalsContact CA-NH2 3.31Å; L434-R510 PolarHBondContact O-NH2 3.5Å
435	I	80.1	Confident	76.6	Confident	1 Å²	1	36.5 Å²	36.5	1%	0.005	19%	0.186	C	C	.	.	H	α-helix	trans	-77.5	-39.5	-176.1	-59.1	160.3	0	0	0	109.7	Y13 Y380 L383 L384 C387 D432 S437 Q438 C439	Y13-I435 HydrophobicContact CE1-CD1 4.28Å; Y380-I435 HydrophobicContact CD2-CD1 4.39Å; Y380-I435 HydrophobicContact CE2-CD1 3.53Å; L383-I435 HydrophobicContact CD1-CG2 4.11Å; L383-I435 HydrophobicContact CD2-CB 3.89Å; L383-I435 HydrophobicContact CD2-CD1 4.39Å; L383-I435 HydrophobicContact CD2-CG2 4.03Å; L383-I435 HydrophobicContact CG-CB 4.1Å; L383-I435 HydrophobicContact CG-CG2 3.64Å; L384-I435 HydrophobicContact CD2-CD1 3.59Å; C387-I435 HydrophobicContact CB-CG2 3.94Å; D432-I435 HydrophobicContact CB-CD1 4.28Å; D432-I435 PolarHBondContact O-N 3.37Å; D432-I435 VanDerWaalsContact O-N 3.11Å; I435-S437 VanDerWaalsContact C-N 3.3Å; I435-S437 PolarHBondContact O-N 2.96Å; I435-Q438 WeakPolarHBondContact O-CA 3.33Å; I435-Q438 WeakPolarHBondContact O-CB 3.23Å; I435-Q438 PolarHBondContact O-N 3.37Å; I435-C439 PolarHBondContact O-N 2.81Å; I435-C439 PolarHBondContact O-SG 3.39Å; I435-C439 VanDerWaalsContact O-SG 3.37Å
436	I	81.2	Confident	77.5	Confident	4 Å²	4	36 Å²	36	2%	0.021	18%	0.184	C	C	.	.	H	α-helix	trans	-58.4	-44.5	176.6	-60.5	162.5	0	0	0	110.8	L383 L430 D432 Q438 C439 I440 W505	L383-I436 HydrophobicContact CD1-CG1 3.99Å; L383-I436 HydrophobicContact CD2-CG1 3.93Å; L430-I436 HydrophobicContact CB-CD1 3.66Å; L430-I436 HydrophobicContact CD1-CD1 4.47Å; D432-I436 WeakPolarHBondContact O-CD1 3.49Å; D432-I436 WeakPolarHBondContact O-CG1 3.44Å; D432-I436 PolarHBondContact O-N 2.97Å; I436-Q438 VanDerWaalsContact C-N 3.32Å; I436-Q438 PolarHBondContact O-N 2.76Å; I436-C439 WeakPolarHBondContact O-CB 3.21Å; I436-C439 PolarHBondContact O-N 3.41Å; I436-I440 HydrophobicContact CG2-CD1 3.97Å; I436-I440 PolarHBondContact O-N 3.49Å; I436-W505 HydrophobicContact CG2-CH2 3.91Å; I436-W505 HydrophobicContact CG2-CZ2 4.4Å
437	S	80.3	Confident	78.7	Confident	2 Å²	2	33.6 Å²	33.6	1%	0.014	18%	0.175	C	C	.	.	H	α-helix	trans	-64.3	-35.2	175.3	51.7	0	0	0	0	112.7	S433 L434 I435 I440 F441 Y506 R510	S433-S437 VanDerWaalsContact O-CB 3.29Å; S433-S437 WeakPolarHBondContact O-CB 3.33Å; S433-S437 PolarHBondContact O-N 3.28Å; S433-S437 PolarHBondContact O-OG 3.38Å; L434-S437 PolarHBondContact O-OG 3.09Å; I435-S437 VanDerWaalsContact C-N 3.3Å; I435-S437 PolarHBondContact O-N 2.96Å; S437-I440 PolarHBondContact O-N 3.29Å; S437-F441 WeakPolarHBondContact O-CB 3.23Å; S437-F441 PolarHBondContact O-N 3.06Å; S437-Y506 VanDerWaalsContact O-CE2 3.23Å; S437-Y506 WeakPolarHBondContact O-CE2 3.29Å; S437-R510 PolarHBondContact OG-NE 2.96Å; S437-R510 PolarHBondContact OG-NH2 2.76Å
438	Q	85.1	Confident	79.9	Confident	63 Å²	63	32.9 Å²	32.9	29%	0.294	17%	0.17	S	C	.	.	H	α-helix	trans	-65	-44.6	172.6	-74.2	175.9	-18.5	0	0	111.9	L434 I435 I436 I440 F441 Y442	L434-Q438 WeakPolarHBondContact O-CG 3.19Å; L434-Q438 PolarHBondContact O-N 3.39Å; I435-Q438 WeakPolarHBondContact O-CA 3.33Å; I435-Q438 WeakPolarHBondContact O-CB 3.23Å; I435-Q438 PolarHBondContact O-N 3.37Å; I436-Q438 VanDerWaalsContact C-N 3.32Å; I436-Q438 PolarHBondContact O-N 2.76Å; Q438-I440 PolarHBondContact O-N 2.63Å; Q438-F441 PolarHBondContact O-N 3.31Å; Q438-Y442 HydrophobicContact CB-CE2 4.33Å; Q438-Y442 WeakPolarHBondContact O-CD2 3.39Å; Q438-Y442 PolarHBondContact O-N 3.32Å
439	C	88.2	Confident	81.4	Confident	0 Å²	0	32.7 Å²	32.7	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-57.4	-48.8	175.1	-66	0	0	0	0	111.1	L390 L424 I435 I436 F441 Y442 I443	L390-C439 HydrophobicContact CD1-CB 3.74Å; L424-C439 HydrophobicContact CD1-CB 3.85Å; I435-C439 PolarHBondContact O-N 2.81Å; I435-C439 PolarHBondContact O-SG 3.39Å; I435-C439 VanDerWaalsContact O-SG 3.37Å; I436-C439 WeakPolarHBondContact O-CB 3.21Å; I436-C439 PolarHBondContact O-N 3.41Å; C439-F441 VanDerWaalsContact C-N 3.33Å; C439-F441 PolarHBondContact O-N 2.98Å; C439-Y442 PolarHBondContact O-N 2.83Å; C439-I443 WeakPolarHBondContact O-CG1 3.38Å; C439-I443 PolarHBondContact O-N 3.06Å
440	I	87.6	Confident	82.9	Confident	0 Å²	0	28.1 Å²	28.1	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-63.9	-40	179.4	-72.6	170	0	0	0	111.2	F425 I436 S437 Q438 Y442 I443 I444 L502 W505 Y506	F425-I440 HydrophobicContact CB-CD1 4.37Å; I436-I440 HydrophobicContact CG2-CD1 3.97Å; I436-I440 PolarHBondContact O-N 3.49Å; S437-I440 PolarHBondContact O-N 3.29Å; Q438-I440 PolarHBondContact O-N 2.63Å; I440-Y442 PolarHBondContact O-N 3.14Å; I440-I443 PolarHBondContact O-N 3.01Å; I440-I444 HydrophobicContact CG2-CD1 3.88Å; I440-I444 HydrophobicContact CG2-CG1 4.46Å; I440-I444 VanDerWaalsContact O-CG1 3.31Å; I440-I444 WeakPolarHBondContact O-CG1 3.29Å; I440-I444 PolarHBondContact O-N 2.91Å; I440-L502 HydrophobicContact CG2-CD2 4.41Å; I440-W505 HydrophobicContact CB-CE3 4.39Å; I440-W505 HydrophobicContact CB-CZ3 3.9Å; I440-W505 HydrophobicContact CD1-CD2 4.25Å; I440-W505 HydrophobicContact CD1-CE3 3.45Å; I440-W505 VanDerWaalsContact CD1-CE3 3.45Å; I440-W505 HydrophobicContact CD1-CH2 3.58Å; I440-W505 HydrophobicContact CD1-CZ2 4.34Å; I440-W505 HydrophobicContact CD1-CZ3 3.09Å; I440-W505 HydrophobicContact CG1-CE3 4.46Å; I440-W505 HydrophobicContact CG1-CZ3 4.02Å; I440-W505 HydrophobicContact CG2-CE3 3.98Å; I440-W505 HydrophobicContact CG2-CZ3 3.96Å; I440-Y506 HydrophobicContact CG2-CD2 4.28Å
441	F	87.7	Confident	84.3	Confident	35 Å²	35	26.4 Å²	26.4	15%	0.154	14%	0.135	C	C	.	.	H	α-helix	trans	-61.2	-44.7	173.5	-175.8	-116.9	0	0	0	112.3	S437 Q438 C439 I443 I444 R445 Y506 E519	S437-F441 WeakPolarHBondContact O-CB 3.23Å; S437-F441 PolarHBondContact O-N 3.06Å; Q438-F441 PolarHBondContact O-N 3.31Å; C439-F441 VanDerWaalsContact C-N 3.33Å; C439-F441 PolarHBondContact O-N 2.98Å; F441-I443 VanDerWaalsContact C-N 3.35Å; F441-I443 PolarHBondContact O-N 3.31Å; F441-I444 PolarHBondContact O-N 3.43Å; F441-R445 VanDerWaalsContact CE1-CD 3.46Å; F441-R445 HydrophobicContact CE1-CG 4.31Å; F441-R445 HydrophobicContact CE2-CG 4.22Å; F441-R445 HydrophobicContact CZ-CG 4.11Å; F441-R445 WeakPolarHBondContact O-CG 3.48Å; F441-R445 PolarHBondContact O-N 3.37Å; F441-Y506 HydrophobicContact CB-CD2 4.35Å; F441-Y506 HydrophobicContact CB-CE2 3.66Å; F441-Y506 AromaticContact CD2-CE1 3.98Å; F441-Y506 HydrophobicContact CD2-CE1 3.98Å; F441-Y506 HydrophobicContact CD2-CE2 4.32Å; F441-Y506 AromaticContact CD2-CZ 3.71Å; F441-Y506 HydrophobicContact CG-CE2 4.32Å; F441-E519 HydrophobicContact CE2-CB 4.16Å; F441-E519 HydrophobicContact CZ-CB 4.36Å; F441-E519 HydrophobicContact CZ-CG 4.44Å
442	Y	91.2	Very high	85.5	Confident	45 Å²	45	23 Å²	23	18%	0.176	11%	0.112	C	C	.	.	H	α-helix	trans	-62	-42.7	175.1	-68.9	-49.8	0	0	0	111.7	L390 K391 L394 Q438 C439 I440 I444 R445 I446	L390-Y442 HydrophobicContact CB-CD2 4.3Å; L390-Y442 HydrophobicContact CB-CG 4.36Å; K391-Y442 HydrophobicContact CB-CE1 4.46Å; K391-Y442 HydrophobicContact CB-CE2 4.12Å; L394-Y442 HydrophobicContact CD2-CD1 3.75Å; L394-Y442 HydrophobicContact CD2-CE1 4.21Å; Q438-Y442 HydrophobicContact CB-CE2 4.33Å; Q438-Y442 WeakPolarHBondContact O-CD2 3.39Å; Q438-Y442 PolarHBondContact O-N 3.32Å; C439-Y442 PolarHBondContact O-N 2.83Å; I440-Y442 PolarHBondContact O-N 3.14Å; Y442-I444 PolarHBondContact O-N 2.99Å; Y442-R445 PolarHBondContact O-N 3.5Å; Y442-I446 WeakPolarHBondContact O-CB 3.13Å; Y442-I446 VanDerWaalsContact O-CD1 3.32Å; Y442-I446 WeakPolarHBondContact O-CD1 3.3Å; Y442-I446 WeakPolarHBondContact O-CG1 3.33Å; Y442-I446 PolarHBondContact O-N 3.47Å
443	I	92.8	Very high	85.8	Confident	0 Å²	0	22.4 Å²	22.4	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-57.3	-49.1	175.5	-70.7	167.6	0	0	0	110.7	L390 L417 L420 A421 L424 C439 I440 F441 R445 I446 I447	L390-I443 HydrophobicContact CD1-CD1 4.06Å; L390-I443 HydrophobicContact CD1-CG1 3.8Å; L390-I443 HydrophobicContact CD2-CD1 4.48Å; L390-I443 HydrophobicContact CD2-CG1 3.7Å; L390-I443 HydrophobicContact CG-CG1 4.41Å; L417-I443 HydrophobicContact CB-CG2 3.93Å; L417-I443 HydrophobicContact CD2-CG1 4.14Å; L420-I443 HydrophobicContact CD2-CD1 4.15Å; L420-I443 HydrophobicContact CG-CD1 4.19Å; A421-I443 HydrophobicContact CB-CD1 3.74Å; A421-I443 HydrophobicContact CB-CG2 4.02Å; L424-I443 HydrophobicContact CD1-CD1 4.18Å; C439-I443 WeakPolarHBondContact O-CG1 3.38Å; C439-I443 PolarHBondContact O-N 3.06Å; I440-I443 PolarHBondContact O-N 3.01Å; F441-I443 VanDerWaalsContact C-N 3.35Å; F441-I443 PolarHBondContact O-N 3.31Å; I443-R445 VanDerWaalsContact C-N 3.34Å; I443-R445 PolarHBondContact O-N 2.82Å; I443-I446 PolarHBondContact O-N 3.42Å; I443-I447 HydrophobicContact CG2-CD1 3.77Å; I443-I447 HydrophobicContact CG2-CG1 4.49Å; I443-I447 WeakPolarHBondContact O-CG1 3.44Å; I443-I447 PolarHBondContact O-N 3.2Å
444	I	90.2	Very high	85.7	Confident	0 Å²	0	22 Å²	22	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-59.6	-45.4	179.3	-67.6	166.3	0	0	0	110.9	I440 F441 Y442 I447 G448 F499 L502 I503 L520	I440-I444 HydrophobicContact CG2-CD1 3.88Å; I440-I444 HydrophobicContact CG2-CG1 4.46Å; I440-I444 VanDerWaalsContact O-CG1 3.31Å; I440-I444 WeakPolarHBondContact O-CG1 3.29Å; I440-I444 PolarHBondContact O-N 2.91Å; F441-I444 PolarHBondContact O-N 3.43Å; Y442-I444 PolarHBondContact O-N 2.99Å; I444-I447 PolarHBondContact O-N 3.27Å; I444-G448 PolarHBondContact O-N 3.46Å; I444-F499 HydrophobicContact CB-CE2 4.32Å; I444-F499 HydrophobicContact CG1-CE2 4.15Å; I444-F499 HydrophobicContact CG2-CE2 4.09Å; I444-F499 HydrophobicContact CG2-CZ 3.89Å; I444-L502 HydrophobicContact CD1-CB 4.43Å; I444-I503 HydrophobicContact CD1-CG1 4.38Å; I444-L520 HydrophobicContact CD1-CD2 3.73Å; I444-L520 HydrophobicContact CG2-CD2 3.87Å
445	R	91	Very high	85	Confident	59 Å²	59	21.2 Å²	21.2	22%	0.223	9%	0.091	C	C	.	.	H	α-helix	trans	-65.8	-40.7	178.2	-70	-174.6	91.4	-164.4	5.4	113	L394 F441 Y442 I443 I447 G448 C449 E519	L394-R445 HydrophobicContact CD1-CB 4.01Å; L394-R445 HydrophobicContact CD2-CB 4.3Å; F441-R445 VanDerWaalsContact CE1-CD 3.46Å; F441-R445 HydrophobicContact CE1-CG 4.31Å; F441-R445 HydrophobicContact CE2-CG 4.22Å; F441-R445 HydrophobicContact CZ-CG 4.11Å; F441-R445 WeakPolarHBondContact O-CG 3.48Å; F441-R445 PolarHBondContact O-N 3.37Å; Y442-R445 PolarHBondContact O-N 3.5Å; I443-R445 VanDerWaalsContact C-N 3.34Å; I443-R445 PolarHBondContact O-N 2.82Å; R445-I447 VanDerWaalsContact C-N 3.35Å; R445-G448 PolarHBondContact O-N 3.42Å; R445-C449 WeakPolarHBondContact O-CB 3.49Å; R445-C449 PolarHBondContact O-N 3.42Å; R445-C449 PolarHBondContact O-SG 2.92Å; R445-E519 IonicContact CZ-OE1 3.36Å; R445-E519 IonicContact CZ-OE2 3.92Å; R445-E519 IonicContact NE-OE1 2.82Å; R445-E519 IonicContact NE-OE2 3.2Å; R445-E519 PolarHBondContact NE-OE2 2.78Å; R445-E519 IonicContact NH2-OE1 3.61Å; R445-E519 PolarHBondContact NH2-OE1 2.98Å; R445-E519 IonicContact NH2-OE2 3.31Å; R445-E519 PolarHBondContact NH2-OE2 2.84Å
446	I	92.1	Very high	83.9	Confident	0 Å²	0	24.7 Å²	24.7	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-60.5	-49.4	177.6	-71.5	160.3	0	0	0	109.4	L390 L393 L394 I397 L417 Y442 I443 G448 C449 I450	L390-I446 HydrophobicContact CB-CD1 4.23Å; L390-I446 HydrophobicContact CD2-CD1 3.82Å; L390-I446 WeakPolarHBondContact O-CD1 3.42Å; L393-I446 HydrophobicContact CB-CD1 4.27Å; L393-I446 HydrophobicContact CD2-CD1 4.08Å; L393-I446 HydrophobicContact CD2-CG2 4.32Å; L393-I446 HydrophobicContact CG-CD1 4.19Å; L393-I446 HydrophobicContact CG-CG2 4.46Å; L394-I446 HydrophobicContact CB-CD1 4.32Å; L394-I446 HydrophobicContact CB-CG1 3.79Å; L394-I446 HydrophobicContact CD1-CG1 3.99Å; L394-I446 HydrophobicContact CG-CG1 4.46Å; I397-I446 HydrophobicContact CD1-CG2 3.44Å; I397-I446 VanDerWaalsContact CD1-CG2 3.44Å; L417-I446 HydrophobicContact CD1-CB 4.14Å; L417-I446 HydrophobicContact CD1-CG2 3.37Å; Y442-I446 WeakPolarHBondContact O-CB 3.13Å; Y442-I446 VanDerWaalsContact O-CD1 3.32Å; Y442-I446 WeakPolarHBondContact O-CD1 3.3Å; Y442-I446 WeakPolarHBondContact O-CG1 3.33Å; Y442-I446 PolarHBondContact O-N 3.47Å; I443-I446 PolarHBondContact O-N 3.42Å; I446-G448 VanDerWaalsContact C-N 3.34Å; I446-G448 PolarHBondContact O-N 3.45Å; I446-C449 PolarHBondContact O-N 2.93Å; I446-I450 HydrophobicContact CG2-CD1 3.72Å; I446-I450 HydrophobicContact CG2-CG1 4.38Å; I446-I450 VanDerWaalsContact O-CG1 3.27Å; I446-I450 WeakPolarHBondContact O-CG1 3.31Å; I446-I450 PolarHBondContact O-N 3.37Å
447	I	91.5	Very high	82.5	Confident	0 Å²	0	26.9 Å²	26.9	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-58.1	-48.3	176.3	-67.8	169.5	0	0	0	110	L417 L418 I443 I444 R445 C449 I450 C451 F499 F527	L417-I447 HydrophobicContact CB-CD1 4.2Å; L417-I447 HydrophobicContact CB-CG1 4.29Å; L417-I447 HydrophobicContact CD1-CG1 4.05Å; L418-I447 HydrophobicContact CD2-CD1 3.81Å; L418-I447 HydrophobicContact CG-CD1 3.99Å; I443-I447 HydrophobicContact CG2-CD1 3.77Å; I443-I447 HydrophobicContact CG2-CG1 4.49Å; I443-I447 WeakPolarHBondContact O-CG1 3.44Å; I443-I447 PolarHBondContact O-N 3.2Å; I444-I447 PolarHBondContact O-N 3.27Å; R445-I447 VanDerWaalsContact C-N 3.35Å; I447-C449 VanDerWaalsContact C-N 3.34Å; I447-C449 PolarHBondContact O-N 2.87Å; I447-I450 PolarHBondContact O-N 3.44Å; I447-C451 WeakPolarHBondContact O-CB 3.36Å; I447-C451 PolarHBondContact O-N 3.01Å; I447-C451 PolarHBondContact O-SG 3.24Å; I447-F499 HydrophobicContact CB-CE2 4.02Å; I447-F499 HydrophobicContact CB-CZ 4.46Å; I447-F499 HydrophobicContact CD1-CD2 4.05Å; I447-F499 HydrophobicContact CD1-CE2 3.91Å; I447-F499 HydrophobicContact CG2-CD2 4.31Å; I447-F499 HydrophobicContact CG2-CE2 3.8Å; I447-F499 HydrophobicContact CG2-CZ 4.05Å; I447-F527 HydrophobicContact CG2-CD2 3.56Å; I447-F527 HydrophobicContact CG2-CE2 4.03Å
448	G	88.5	Confident	81	Confident	0 Å²	0	31.9 Å²	31.9	0%	0	14%	0.139	C	C	.	.	H	α-helix	trans	-56.5	-44.2	176.5	0	0	0	0	0	113.3	I444 R445 I446 C451 Y452	I444-G448 PolarHBondContact O-N 3.46Å; R445-G448 PolarHBondContact O-N 3.42Å; I446-G448 VanDerWaalsContact C-N 3.34Å; I446-G448 PolarHBondContact O-N 3.45Å; G448-C451 PolarHBondContact O-N 2.99Å; G448-Y452 VanDerWaalsContact O-CB 3.26Å; G448-Y452 WeakPolarHBondContact O-CB 3.08Å; G448-Y452 PolarHBondContact O-N 3.41Å
449	C	88.9	Confident	78.9	Confident	5 Å²	5	34 Å²	34	3%	0.034	15%	0.149	C	C	.	.	H	α-helix	trans	-64.4	-45.8	176.4	-73.4	0	0	0	0	112.5	I397 R445 I446 I447 C451 Y452 Y453	I397-C449 HydrophobicContact CG2-CB 3.8Å; R445-C449 WeakPolarHBondContact O-CB 3.49Å; R445-C449 PolarHBondContact O-N 3.42Å; R445-C449 PolarHBondContact O-SG 2.92Å; I446-C449 PolarHBondContact O-N 2.93Å; I447-C449 VanDerWaalsContact C-N 3.34Å; I447-C449 PolarHBondContact O-N 2.87Å; C449-C451 VanDerWaalsContact C-N 3.31Å; C449-C451 PolarHBondContact O-N 2.9Å; C449-Y452 PolarHBondContact O-N 3.35Å; C449-Y453 HydrophobicContact CB-CD2 4.42Å; C449-Y453 HydrophobicContact CB-CE2 4.05Å; C449-Y453 WeakPolarHBondContact O-CD2 3.29Å; C449-Y453 PolarHBondContact O-N 2.9Å
450	I	87.4	Confident	76.1	Confident	3 Å²	3	39.5 Å²	39.5	2%	0.015	18%	0.175	C	C	.	.	H	α-helix	trans	-56.3	-50.1	176.6	-69.5	165.1	0	0	0	109.8	I397 N410 L413 I414 L417 I446 I447 Y453 H454	I397-I450 HydrophobicContact CD1-CD1 4.08Å; I397-I450 HydrophobicContact CD1-CG1 4Å; I397-I450 HydrophobicContact CG2-CG1 4.24Å; N410-I450 HydrophobicContact CB-CG2 3.73Å; N410-I450 VanDerWaalsContact CG-CG2 3.46Å; N410-I450 WeakPolarHBondContact OD1-CG2 3.07Å; L413-I450 HydrophobicContact CD2-CD1 3.67Å; L413-I450 HydrophobicContact CG-CD1 4.03Å; I414-I450 HydrophobicContact CD1-CG2 3.91Å; I414-I450 HydrophobicContact CG1-CD1 4.32Å; I414-I450 HydrophobicContact CG1-CG2 4.2Å; L417-I450 HydrophobicContact CD1-CD1 4.32Å; I446-I450 HydrophobicContact CG2-CD1 3.72Å; I446-I450 HydrophobicContact CG2-CG1 4.38Å; I446-I450 VanDerWaalsContact O-CG1 3.27Å; I446-I450 WeakPolarHBondContact O-CG1 3.31Å; I446-I450 PolarHBondContact O-N 3.37Å; I447-I450 PolarHBondContact O-N 3.44Å; I450-Y453 PolarHBondContact O-N 2.97Å; I450-H454 PolarHBondContact O-N 3.25Å
451	C	86.4	Confident	73.4	Confident	1 Å²	1	46.4 Å²	46.4	1%	0.007	21%	0.207	C	C	.	.	H	α-helix	trans	-64.2	-43.1	-178.8	-67.5	0	0	0	0	112.4	I447 G448 C449 Y453 H455 N526 Y530	I447-C451 WeakPolarHBondContact O-CB 3.36Å; I447-C451 PolarHBondContact O-N 3.01Å; I447-C451 PolarHBondContact O-SG 3.24Å; G448-C451 PolarHBondContact O-N 2.99Å; C449-C451 VanDerWaalsContact C-N 3.31Å; C449-C451 PolarHBondContact O-N 2.9Å; C451-Y453 PolarHBondContact O-N 3.44Å; C451-H455 PolarHBondContact O-N 3.01Å; C451-N526 HydrophobicContact CB-CB 3.95Å; C451-N526 WeakPolarHBondContact CB-O 3.37Å; C451-Y530 HydrophobicContact CB-CD2 4.27Å; C451-Y530 HydrophobicContact CB-CG 4.08Å
452	Y	83.9	Confident	70.5	Confident	78 Å²	78	51.8 Å²	51.8	31%	0.306	23%	0.233	S	C	.	.	H	α-helix	trans	-59.7	-46.2	177.5	173	-104.5	0	0	0	112.2	G448 C449 H454 H455 Y456 W522	G448-Y452 VanDerWaalsContact O-CB 3.26Å; G448-Y452 WeakPolarHBondContact O-CB 3.08Å; G448-Y452 PolarHBondContact O-N 3.41Å; C449-Y452 PolarHBondContact O-N 3.35Å; Y452-H454 PolarHBondContact O-N 3.33Å; Y452-H455 PolarHBondContact O-N 2.82Å; Y452-Y456 HydrophobicContact CE1-CD2 4.41Å; Y452-Y456 HydrophobicContact CE2-CD2 4.25Å; Y452-Y456 AromaticContact CZ-CD2 3.82Å; Y452-Y456 PolarHBondContact O-N 2.84Å; Y452-Y456 WeakPolarHBondContact OH-CE2 3.3Å; Y452-W522 HydrophobicContact CD1-CZ2 4.35Å; Y452-W522 HydrophobicContact CD2-CZ2 4.12Å; Y452-W522 AromaticContact CG-CZ2 3.84Å; Y452-W522 HydrophobicContact CG-CZ2 3.84Å
453	Y	77.8	Confident	67.3	Low	40 Å²	40	57.6 Å²	57.6	16%	0.157	26%	0.261	C	S	.	.	H	α-helix	trans	-69	-36.6	-174.8	-69.4	-47.5	0	0	0	113.5	I397 Q398 K403 C449 I450 C451 H455 Y456 D457	I397-Y453 HydrophobicContact CG2-CD2 4.16Å; I397-Y453 HydrophobicContact CG2-CE2 4.03Å; I397-Y453 WeakPolarHBondContact O-CE2 2.97Å; Q398-Y453 WeakPolarHBondContact CA-OH 3.41Å; K403-Y453 HydrophobicContact CD-CD1 4.09Å; K403-Y453 HydrophobicContact CD-CG 4.19Å; K403-Y453 HydrophobicContact CG-CG 4.43Å; C449-Y453 HydrophobicContact CB-CD2 4.42Å; C449-Y453 HydrophobicContact CB-CE2 4.05Å; C449-Y453 WeakPolarHBondContact O-CD2 3.29Å; C449-Y453 PolarHBondContact O-N 2.9Å; I450-Y453 PolarHBondContact O-N 2.97Å; C451-Y453 PolarHBondContact O-N 3.44Å; Y453-H455 VanDerWaalsContact C-N 3.32Å; Y453-H455 PolarHBondContact O-N 3.43Å; Y453-Y456 PolarHBondContact O-N 3.39Å; Y453-D457 PolarHBondContact O-N 2.84Å
454	H	70.5	Confident	64.2	Low	54 Å²	54	62.5 Å²	62.5	25%	0.25	29%	0.292	C	S	.	.	H	α-helix	trans	-64.4	-38.1	176.6	-174.6	-86.6	0	0	0	112.4	I450 Y452 Y456 H458 Y530	I450-H454 PolarHBondContact O-N 3.25Å; Y452-H454 PolarHBondContact O-N 3.33Å; H454-Y456 VanDerWaalsContact C-N 3.3Å; H454-Y456 PolarHBondContact O-N 2.94Å; H454-H458 AromaticContact CE1-CD2 3.44Å; H454-H458 PolarHBondContact CE1-CD2 3.41Å; H454-H458 VanDerWaalsContact CE1-CD2 3.44Å; H454-H458 AromaticContact CE1-NE2 3.31Å; H454-H458 PolarHBondContact CE1-NE2 3.44Å; H454-H458 VanDerWaalsContact CE1-NE2 3.31Å; H454-H458 AromaticContact ND1-CD2 3.73Å; H454-H458 AromaticContact NE2-NE2 3.7Å; H454-Y530 HydrophobicContact CB-CD2 3.61Å; H454-Y530 HydrophobicContact CB-CE2 3.45Å; H454-Y530 VanDerWaalsContact CB-CE2 3.45Å; H454-Y530 AromaticContact CD2-CE2 3.78Å; H454-Y530 AromaticContact CG-CD2 3.77Å; H454-Y530 AromaticContact CG-CE2 3.36Å; H454-Y530 AromaticContact ND1-CD2 3.83Å; H454-Y530 AromaticContact ND1-CE2 3.68Å
455	H	62.8	Low	61.1	Low	56 Å²	56	66.7 Å²	66.7	26%	0.259	32%	0.32	S	S	.	.	H	α-helix	trans	-67.7	-34	176.7	-162.7	67	0	0	0	112.2	C451 Y452 Y453 H459 Q529	C451-H455 PolarHBondContact O-N 3.01Å; Y452-H455 PolarHBondContact O-N 2.82Å; Y453-H455 VanDerWaalsContact C-N 3.32Å; Y453-H455 PolarHBondContact O-N 3.43Å; H455-H459 AromaticContact CD2-CD2 3.75Å; H455-H459 AromaticContact CD2-NE2 3.74Å; H455-H459 AromaticContact CE1-CD2 3.98Å; H455-H459 AromaticContact CE1-NE2 3.41Å; H455-H459 PolarHBondContact CE1-NE2 3.14Å; H455-H459 AromaticContact NE2-CD2 3.42Å; H455-H459 PolarHBondContact NE2-CD2 2.99Å; H455-H459 AromaticContact NE2-NE2 2.91Å; H455-H459 PolarHBondContact NE2-NE2 2.89Å; H455-H459 PolarHBondContact O-CD2 3.32Å; H455-Q529 VanDerWaalsContact CD2-CD 3.49Å; H455-Q529 PolarHBondContact CD2-NE2 3.29Å; H455-Q529 PolarHBondContact CE1-NE2 2.83Å; H455-Q529 PolarHBondContact NE2-NE2 3.47Å
456	Y	56.3	Low	58	Low	73 Å²	73	70.1 Å²	70.1	29%	0.286	35%	0.35	S	S	.	.	H	α-helix	trans	-68	-35.6	-179.3	-146	-87.8	0	0	0	113.1	Y452 Y453 H454 H460 K686	Y452-Y456 HydrophobicContact CE1-CD2 4.41Å; Y452-Y456 HydrophobicContact CE2-CD2 4.25Å; Y452-Y456 AromaticContact CZ-CD2 3.82Å; Y452-Y456 PolarHBondContact O-N 2.84Å; Y452-Y456 WeakPolarHBondContact OH-CE2 3.3Å; Y453-Y456 PolarHBondContact O-N 3.39Å; H454-Y456 VanDerWaalsContact C-N 3.3Å; H454-Y456 PolarHBondContact O-N 2.94Å; Y456-H460 AromaticContact CD1-CD2 3.8Å; Y456-H460 AromaticContact CE1-CD2 3.69Å; Y456-H460 AromaticContact CE1-NE2 3.49Å; Y456-H460 WeakPolarHBondContact CE1-NE2 3.41Å; Y456-K686 WeakPolarHBondContact OH-CD 3.47Å; Y456-K686 WeakPolarHBondContact OH-CE 2.99Å; Y456-K686 PolarHBondContact OH-NZ 3.35Å
457	D	52.9	Low	54.9	Low	51 Å²	51	80.3 Å²	80.3	27%	0.273	39%	0.39	S	S	.	.	H	α-helix	trans	-75	-33.3	-177.5	-72.6	-17.9	0	0	0	112.6	Y453 H459 H460 Q461	Y453-D457 PolarHBondContact O-N 2.84Å; D457-H459 PolarHBondContact O-N 3.15Å; D457-H460 PolarHBondContact O-N 3.46Å; D457-Q461 PolarHBondContact O-N 2.97Å
458	H	48.7	Very low	51.7	Low	107 Å²	107	88.6 Å²	88.6	50%	0.495	43%	0.428	S	S	.	.	H	α-helix	trans	-67.9	-31.6	178.5	-86.4	-63.4	0	0	0	114	H454	H454-H458 AromaticContact CE1-CD2 3.44Å; H454-H458 PolarHBondContact CE1-CD2 3.41Å; H454-H458 VanDerWaalsContact CE1-CD2 3.44Å; H454-H458 AromaticContact CE1-NE2 3.31Å; H454-H458 PolarHBondContact CE1-NE2 3.44Å; H454-H458 VanDerWaalsContact CE1-NE2 3.31Å; H454-H458 AromaticContact ND1-CD2 3.73Å; H454-H458 AromaticContact NE2-NE2 3.7Å
459	H	39.5	Very low	48.7	Very low	106 Å²	106	96.9 Å²	96.9	49%	0.491	47%	0.467	S	S	.	.	H	α-helix	trans	-73.8	-29.8	176.4	-78.4	-69.7	0	0	0	113	H455 D457	H455-H459 AromaticContact CD2-CD2 3.75Å; H455-H459 AromaticContact CD2-NE2 3.74Å; H455-H459 AromaticContact CE1-CD2 3.98Å; H455-H459 AromaticContact CE1-NE2 3.41Å; H455-H459 PolarHBondContact CE1-NE2 3.14Å; H455-H459 AromaticContact NE2-CD2 3.42Å; H455-H459 PolarHBondContact NE2-CD2 2.99Å; H455-H459 AromaticContact NE2-NE2 2.91Å; H455-H459 PolarHBondContact NE2-NE2 2.89Å; H455-H459 PolarHBondContact O-CD2 3.32Å; D457-H459 PolarHBondContact O-N 3.15Å
460	H	30.2	Very low	45.7	Very low	117 Å²	117	105.7 Å²	105.7	54%	0.542	51%	0.507	S	S	.	.	H	α-helix	trans	-81.3	-20.8	-180	-84.8	-58.4	0	0	0	114.2	Y456 D457 Q462	Y456-H460 AromaticContact CD1-CD2 3.8Å; Y456-H460 AromaticContact CE1-CD2 3.69Å; Y456-H460 AromaticContact CE1-NE2 3.49Å; Y456-H460 WeakPolarHBondContact CE1-NE2 3.41Å; D457-H460 PolarHBondContact O-N 3.46Å; H460-Q462 VanDerWaalsContact C-N 3.29Å; H460-Q462 PolarHBondContact O-N 3.07Å
461	Q	31.5	Very low	42.6	Very low	145 Å²	145	115.2 Å²	115.2	68%	0.678	55%	0.551	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.7	-7.8	177.9	-71.6	-174.9	3.2	0	0	114.4	D457 H463	D457-Q461 PolarHBondContact O-N 2.97Å; Q461-H463 PolarHBondContact O-N 2.95Å
462	Q	27.2	Very low	39.7	Very low	148 Å²	148	123.6 Å²	123.6	69%	0.692	59%	0.59	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.7	-3.9	178.6	-68.2	-171.4	-3.8	0	0	114.5	H460 P464	H460-Q462 VanDerWaalsContact C-N 3.29Å; H460-Q462 PolarHBondContact O-N 3.07Å; Q462-P464 WeakPolarHBondContact O-CD 3.38Å
463	H	23.9	Very low	36.8	Very low	167 Å²	167	128.9 Å²	128.9	77%	0.773	62%	0.618	S	S	*	*			trans	-121.8	75.6	169.7	-67.9	-53.1	0	0	0	111.1	Q461 P465	Q461-H463 PolarHBondContact O-N 2.95Å; H463-P465 WeakPolarHBondContact O-CD 3.48Å
464	P	26.1	Very low	34.2	Very low	102 Å²	102	134.5 Å²	134.5	66%	0.662	65%	0.646	S	S	*	*			trans	-65.5	126.8	166.6	27.3	-30.2	0	0	0	108.4	Q462	Q462-P464 WeakPolarHBondContact O-CD 3.38Å
465	P	25.4	Very low	31.9	Very low	88 Å²	88	140.3 Å²	140.3	57%	0.571	67%	0.673	S	S	*	*			trans	-60.3	147.4	167.4	24.7	-30.3	0	0	0	109.1	H463 Y467	H463-P465 WeakPolarHBondContact O-CD 3.48Å; P465-Y467 HydrophobicContact CG-CD2 4.41Å; P465-Y467 HydrophobicContact CG-CE2 4.38Å; P465-Y467 PolarHBondContact O-N 3.13Å
466	P	25.8	Very low	30	Very low	132 Å²	132	144.4 Å²	144.4	86%	0.857	69%	0.692	S	S	*	*			trans	-70.8	102.3	-172.1	29.2	-32.3	0	0	0	109.2
467	Y	27.7	Very low	28.4	Very low	213 Å²	213	148 Å²	148	84%	0.835	71%	0.714	S	S	*	*			trans	-103.6	125.8	166.8	-88.7	-81.8	0	0	0	110.4	P465	P465-Y467 HydrophobicContact CG-CD2 4.41Å; P465-Y467 HydrophobicContact CG-CE2 4.38Å; P465-Y467 PolarHBondContact O-N 3.13Å
468	H	25.1	Very low	26.9	Very low	175 Å²	175	152.4 Å²	152.4	81%	0.81	73%	0.733	S	S	*	*			trans	-55.9	135.5	173	-80.1	-81.1	0	0	0	112.1	H470	H468-H470 PolarHBondContact O-N 3.33Å
469	H	23.7	Very low	25.8	Very low	174 Å²	174	154.8 Å²	154.8	81%	0.806	75%	0.746	S	S	*	*			trans	0.9	101.3	160.4	-67.5	-68.8	0	0	0	117
470	H	26	Very low	24.9	Very low	190 Å²	190	154.5 Å²	154.5	88%	0.88	75%	0.752	S	S	*	*			trans	-151.7	123.5	131.7	-94.8	-62.9	0	0	0	109	H468 Q472	H468-H470 PolarHBondContact O-N 3.33Å; H470-Q472 PolarHBondContact O-N 3.4Å
471	Q	23.5	Very low	24.7	Very low	202 Å²	202	154.7 Å²	154.7	94%	0.944	75%	0.753	S	S	*	*			trans	-54	101	175.3	-71.4	166.8	-28.7	0	0	110.2
472	Q	24.6	Very low	24.5	Very low	177 Å²	177	156 Å²	156	83%	0.827	76%	0.76	S	S	*	*			trans	-123.9	123.6	154.1	-74.5	-173	-2.7	0	0	106.5	H470 Q474	H470-Q472 PolarHBondContact O-N 3.4Å; Q472-Q474 PolarHBondContact O-N 3.27Å
473	Q	23	Very low	24.5	Very low	190 Å²	190	153.4 Å²	153.4	89%	0.888	76%	0.756	S	S	*	*			trans	-51.6	98.1	-179.9	-69.5	161.5	-18.6	0	0	108.9	E475	Q473-E475 VanDerWaalsContact C-N 3.33Å; Q473-E475 PolarHBondContact O-N 3.33Å; Q473-E475 VanDerWaalsContact O-N 3.11Å
474	Q	23.8	Very low	24.8	Very low	158 Å²	158	153 Å²	153	74%	0.738	75%	0.748	S	S	*	*			trans	-68.4	102.8	156.4	-84.7	175.4	-20.8	0	0	104.9	Q472 H476	Q472-Q474 PolarHBondContact O-N 3.27Å; Q474-H476 PolarHBondContact O-N 3.06Å
475	E	22.6	Very low	25	Very low	175 Å²	175	153.2 Å²	153.2	82%	0.818	74%	0.743	S	S	*	*			trans	-59.6	81.6	159.8	-71.9	-179.5	162.6	0	0	106.9	Q473 I477	Q473-E475 VanDerWaalsContact C-N 3.33Å; Q473-E475 PolarHBondContact O-N 3.33Å; Q473-E475 VanDerWaalsContact O-N 3.11Å; E475-I477 VanDerWaalsContact C-N 3.29Å; E475-I477 PolarHBondContact O-N 3.27Å
476	H	22	Very low	25.4	Very low	142 Å²	142	154.7 Å²	154.7	66%	0.657	75%	0.745	S	S	*	*			trans	-56.7	106	152.3	-76.7	-73.8	0	0	0	104.8	Q474 E478	Q474-H476 PolarHBondContact O-N 3.06Å; H476-E478 HydrophobicContact CB-CG 4.25Å; H476-E478 PolarHBondContact O-N 3.41Å
477	I	23.7	Very low	26.3	Very low	148 Å²	148	153.5 Å²	153.5	76%	0.759	73%	0.731	S	S	*	*			trans	-67.4	77.4	162.7	-58.5	172.9	0	0	0	105.1	E475 M479	E475-I477 VanDerWaalsContact C-N 3.29Å; E475-I477 PolarHBondContact O-N 3.27Å; I477-M479 VanDerWaalsContact C-N 3.32Å; I477-M479 HydrophobicContact CG2-CG 4.31Å; I477-M479 PolarHBondContact O-N 2.78Å
478	E	21.7	Very low	27.6	Very low	144 Å²	144	146.3 Å²	146.3	67%	0.673	71%	0.709	S	S	*	*			trans	-62.4	99.4	161.8	-76.8	-175.4	160.5	0	0	105.6	H476 T480	H476-E478 HydrophobicContact CB-CG 4.25Å; H476-E478 PolarHBondContact O-N 3.41Å; E478-T480 HydrophobicContact CB-CG2 3.86Å; E478-T480 HydrophobicContact CG-CG2 4.44Å; E478-T480 PolarHBondContact O-N 2.9Å; E478-T480 PolarHBondContact O-OG1 3.48Å
479	M	24.1	Very low	29.2	Very low	157 Å²	157	141.8 Å²	141.8	77%	0.773	69%	0.691	S	S	*	*			trans	-69.1	61.8	161.4	-75.7	-149.2	-68.4	0	0	109.1	I477	I477-M479 VanDerWaalsContact C-N 3.32Å; I477-M479 HydrophobicContact CG2-CG 4.31Å; I477-M479 PolarHBondContact O-N 2.78Å
480	T	21.8	Very low	31	Very low	100 Å²	100	137 Å²	137	61%	0.613	67%	0.674	S	S	*	*			trans	-101	72.5	177.7	48.1	0	0	0	0	109.8	E478	E478-T480 HydrophobicContact CB-CG2 3.86Å; E478-T480 HydrophobicContact CG-CG2 4.44Å; E478-T480 PolarHBondContact O-N 2.9Å; E478-T480 PolarHBondContact O-OG1 3.48Å
481	Q	25	Very low	32.8	Very low	121 Å²	121	130 Å²	130	57%	0.565	64%	0.643	S	S	*	*			trans	-142.7	109.2	159.8	-67.1	-167.9	2.9	0	0	109.5	Y484	Q481-Y484 HydrophobicContact CB-CD2 4.04Å; Q481-Y484 VanDerWaalsContact O-CB 3.31Å; Q481-Y484 WeakPolarHBondContact O-CB 3.42Å; Q481-Y484 PolarHBondContact O-N 3.4Å
482	Q	27.4	Very low	35.1	Very low	173 Å²	173	120.6 Å²	120.6	81%	0.808	60%	0.599	S	S	*	*	H	α-helix	trans	-54.2	-32.3	-176.7	-72.7	-177.4	-21.5	0	0	116.6	Y484	Q482-Y484 VanDerWaalsContact C-N 3.34Å
483	P	26.9	Very low	37.5	Very low	94 Å²	94	115.6 Å²	115.6	61%	0.61	58%	0.576	S	S	*	*	H	α-helix	trans	-77.9	-16.7	174.1	28.5	-32.9	0	0	0	113.7
484	Y	30.6	Very low	40	Very low	158 Å²	158	107.1 Å²	107.1	62%	0.62	54%	0.539	S	S	*	.	H	α-helix	trans	-68.7	-39.6	175.1	-103.3	-94	0	0	0	111.1	Q481 Q482 I486 N487 T488	Q481-Y484 HydrophobicContact CB-CD2 4.04Å; Q481-Y484 VanDerWaalsContact O-CB 3.31Å; Q481-Y484 WeakPolarHBondContact O-CB 3.42Å; Q481-Y484 PolarHBondContact O-N 3.4Å; Q482-Y484 VanDerWaalsContact C-N 3.34Å; Y484-I486 VanDerWaalsContact C-N 3.35Å; Y484-I486 PolarHBondContact O-N 3.05Å; Y484-N487 PolarHBondContact O-N 3.2Å; Y484-T488 PolarHBondContact O-N 3.29Å; Y484-T488 PolarHBondContact O-OG1 2.89Å
485	I	29.8	Very low	42.7	Very low	106 Å²	106	99.6 Å²	99.6	54%	0.544	50%	0.504	S	S	.	.	H	α-helix	trans	-59.6	-40	-174	-59.8	172.4	0	0	0	112.8	T488 L489	I485-T488 PolarHBondContact O-N 3.32Å; I485-L489 PolarHBondContact O-N 2.99Å
486	I	33.6	Very low	45.6	Very low	120 Å²	120	91.3 Å²	91.3	62%	0.615	47%	0.465	S	S	*	.	H	α-helix	trans	-68	-43.5	-179	-60.7	174.5	0	0	0	110.9	Y484 T488 L489 T490	Y484-I486 VanDerWaalsContact C-N 3.35Å; Y484-I486 PolarHBondContact O-N 3.05Å; I486-T488 VanDerWaalsContact C-N 3.34Å; I486-L489 PolarHBondContact O-N 3Å; I486-T490 PolarHBondContact O-N 3.29Å; I486-T490 VanDerWaalsContact O-N 3.14Å; I486-T490 PolarHBondContact O-OG1 3.42Å
487	N	45.7	Very low	48.3	Very low	106 Å²	106	86.6 Å²	86.6	57%	0.567	44%	0.443	S	S	*	.	H	α-helix	trans	-66	-38.2	173.7	-80.7	-4.9	0	0	0	111.1	Y484 L489 T490 I491	Y484-N487 PolarHBondContact O-N 3.2Å; N487-L489 VanDerWaalsContact C-N 3.32Å; N487-L489 PolarHBondContact O-N 3.28Å; N487-T490 PolarHBondContact O-OG1 3.27Å; N487-T490 VanDerWaalsContact O-OG1 3.08Å; N487-I491 HydrophobicContact CB-CD1 4.46Å; N487-I491 VanDerWaalsContact O-CB 3.25Å; N487-I491 WeakPolarHBondContact O-CB 3.26Å; N487-I491 WeakPolarHBondContact O-CD1 3.43Å; N487-I491 WeakPolarHBondContact O-CG1 3.2Å; N487-I491 PolarHBondContact O-N 3.19Å
488	T	54.4	Low	51	Low	62 Å²	62	80 Å²	80	38%	0.38	41%	0.409	S	S	.	.	H	α-helix	trans	-62.7	-40.6	176	-39.9	0	0	0	0	111.2	Y484 I485 I486 S492	Y484-T488 PolarHBondContact O-N 3.29Å; Y484-T488 PolarHBondContact O-OG1 2.89Å; I485-T488 PolarHBondContact O-N 3.32Å; I486-T488 VanDerWaalsContact C-N 3.34Å; T488-S492 WeakPolarHBondContact O-CB 3.39Å; T488-S492 PolarHBondContact O-N 3.14Å; T488-S492 PolarHBondContact O-OG 2.76Å
489	L	58.3	Low	54	Low	81 Å²	81	73.1 Å²	73.1	42%	0.424	38%	0.377	S	S	.	.	H	α-helix	trans	-66.1	-49.8	-179.9	-164.7	81	0	0	0	111.9	I485 I486 N487 I491 S492 Q493	I485-L489 PolarHBondContact O-N 2.99Å; I486-L489 PolarHBondContact O-N 3Å; N487-L489 VanDerWaalsContact C-N 3.32Å; N487-L489 PolarHBondContact O-N 3.28Å; L489-I491 VanDerWaalsContact C-N 3.33Å; L489-I491 PolarHBondContact O-N 3.17Å; L489-S492 WeakPolarHBondContact CA-OG 2.73Å; L489-S492 PolarHBondContact O-N 3.22Å; L489-S492 VanDerWaalsContact O-N 3.12Å; L489-S492 PolarHBondContact O-OG 3.04Å; L489-Q493 WeakPolarHBondContact O-CG 3.02Å; L489-Q493 PolarHBondContact O-N 3.16Å
490	T	61.4	Low	56.8	Low	73 Å²	73	65.8 Å²	65.8	45%	0.448	34%	0.341	S	S	.	.	H	α-helix	trans	-61.9	-41.6	178.3	52.7	0	0	0	0	111.8	I486 N487 S492 Q493 G494	I486-T490 PolarHBondContact O-N 3.29Å; I486-T490 VanDerWaalsContact O-N 3.14Å; I486-T490 PolarHBondContact O-OG1 3.42Å; N487-T490 PolarHBondContact O-OG1 3.27Å; N487-T490 VanDerWaalsContact O-OG1 3.08Å; T490-S492 VanDerWaalsContact C-N 3.33Å; T490-S492 PolarHBondContact O-N 3.15Å; T490-Q493 PolarHBondContact O-N 2.63Å; T490-G494 PolarHBondContact O-N 3.08Å
491	I	63.9	Low	59.6	Low	43 Å²	43	61.5 Å²	61.5	22%	0.221	31%	0.314	C	S	.	.	H	α-helix	trans	-60.8	-45.5	173.6	-67.5	164.4	0	0	0	110.1	F411 N487 L489 Q493 G494 L495	F411-I491 HydrophobicContact CE2-CG2 4.48Å; F411-I491 HydrophobicContact CZ-CG2 3.97Å; N487-I491 HydrophobicContact CB-CD1 4.46Å; N487-I491 VanDerWaalsContact O-CB 3.25Å; N487-I491 WeakPolarHBondContact O-CB 3.26Å; N487-I491 WeakPolarHBondContact O-CD1 3.43Å; N487-I491 WeakPolarHBondContact O-CG1 3.2Å; N487-I491 PolarHBondContact O-N 3.19Å; L489-I491 VanDerWaalsContact C-N 3.33Å; L489-I491 PolarHBondContact O-N 3.17Å; I491-Q493 VanDerWaalsContact C-N 3.33Å; I491-Q493 PolarHBondContact O-N 2.72Å; I491-G494 PolarHBondContact O-N 2.9Å; I491-L495 HydrophobicContact CG2-CD1 4.02Å; I491-L495 HydrophobicContact CG2-CG 4.43Å; I491-L495 VanDerWaalsContact O-CG 3.27Å; I491-L495 WeakPolarHBondContact O-CG 3.5Å; I491-L495 PolarHBondContact O-N 2.87Å
492	S	73.6	Confident	62.3	Low	4 Å²	4	55.9 Å²	55.9	3%	0.028	29%	0.289	C	S	.	.	H	α-helix	trans	-65.3	-36.1	-178.1	77.5	0	0	0	0	112.6	T488 L489 T490 L495 L496 I533	T488-S492 WeakPolarHBondContact O-CB 3.39Å; T488-S492 PolarHBondContact O-N 3.14Å; T488-S492 PolarHBondContact O-OG 2.76Å; L489-S492 WeakPolarHBondContact CA-OG 2.73Å; L489-S492 PolarHBondContact O-N 3.22Å; L489-S492 VanDerWaalsContact O-N 3.12Å; L489-S492 PolarHBondContact O-OG 3.04Å; T490-S492 VanDerWaalsContact C-N 3.33Å; T490-S492 PolarHBondContact O-N 3.15Å; S492-L495 PolarHBondContact O-N 2.95Å; S492-L496 WeakPolarHBondContact O-CB 3.42Å; S492-L496 PolarHBondContact O-N 3.34Å; S492-I533 VanDerWaalsContact CB-CD1 3.47Å; S492-I533 WeakPolarHBondContact O-CD1 3.12Å; S492-I533 VanDerWaalsContact OG-CD1 3.26Å; S492-I533 WeakPolarHBondContact OG-CD1 3.49Å
493	Q	74.1	Confident	64.9	Low	73 Å²	73	47.7 Å²	47.7	34%	0.341	25%	0.25	S	S	.	.	H	α-helix	trans	-66.9	-44.3	174	-73.8	175.7	-19.8	0	0	112	L489 T490 I491 L495 L496 H497 I533	L489-Q493 WeakPolarHBondContact O-CG 3.02Å; L489-Q493 PolarHBondContact O-N 3.16Å; T490-Q493 PolarHBondContact O-N 2.63Å; I491-Q493 VanDerWaalsContact C-N 3.33Å; I491-Q493 PolarHBondContact O-N 2.72Å; Q493-L495 VanDerWaalsContact C-N 3.31Å; Q493-L495 PolarHBondContact O-N 2.92Å; Q493-L496 WeakPolarHBondContact O-CB 3.47Å; Q493-L496 PolarHBondContact O-N 2.96Å; Q493-L496 VanDerWaalsContact O-N 3.17Å; Q493-H497 PolarHBondContact O-N 3.49Å; Q493-I533 HydrophobicContact CG-CG2 4.36Å
494	G	74.8	Confident	67.2	Low	11 Å²	11	44.3 Å²	44.3	11%	0.113	23%	0.226	C	C	.	.	H	α-helix	trans	-59.9	-41.1	174	0	0	0	0	0	112.3	T490 I491 H497 N498	T490-G494 PolarHBondContact O-N 3.08Å; I491-G494 PolarHBondContact O-N 2.9Å; G494-H497 PolarHBondContact O-N 3.47Å; G494-N498 PolarHBondContact O-N 3.14Å; G494-N498 VanDerWaalsContact O-N 3.07Å; G494-N498 PolarHBondContact O-ND2 3.09Å
495	L	81.3	Confident	69.4	Low	1 Å²	1	37 Å²	37	1%	0.005	20%	0.198	C	C	.	.	H	α-helix	trans	-65.6	-40.6	174.7	-63	171.1	0	0	0	112	L352 F411 Q415 L418 I491 S492 Q493 N498 F499 F527 F531	L352-L495 HydrophobicContact CD1-CD2 4.12Å; F411-L495 HydrophobicContact CE2-CD1 3.93Å; F411-L495 HydrophobicContact CZ-CD1 4.45Å; Q415-L495 HydrophobicContact CG-CD2 4.02Å; L418-L495 HydrophobicContact CD1-CB 4.09Å; L418-L495 HydrophobicContact CD1-CD2 3.57Å; L418-L495 HydrophobicContact CD1-CG 4.4Å; I491-L495 HydrophobicContact CG2-CD1 4.02Å; I491-L495 HydrophobicContact CG2-CG 4.43Å; I491-L495 VanDerWaalsContact O-CG 3.27Å; I491-L495 WeakPolarHBondContact O-CG 3.5Å; I491-L495 PolarHBondContact O-N 2.87Å; S492-L495 PolarHBondContact O-N 2.95Å; Q493-L495 VanDerWaalsContact C-N 3.31Å; Q493-L495 PolarHBondContact O-N 2.92Å; L495-N498 PolarHBondContact O-N 3.46Å; L495-F499 WeakPolarHBondContact O-CB 3.36Å; L495-F499 PolarHBondContact O-N 3.34Å; L495-F527 HydrophobicContact CB-CZ 3.93Å; L495-F531 HydrophobicContact CD1-CE1 4.08Å; L495-F531 HydrophobicContact CD1-CZ 3.91Å
496	L	82.6	Confident	71.6	Confident	0 Å²	0	32.8 Å²	32.8	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-59.9	-46.1	174.3	177.8	63.8	0	0	0	111.2	S492 Q493 N498 F499 L500 L524 F527 I528 I533 I535	S492-L496 WeakPolarHBondContact O-CB 3.42Å; S492-L496 PolarHBondContact O-N 3.34Å; Q493-L496 WeakPolarHBondContact O-CB 3.47Å; Q493-L496 PolarHBondContact O-N 2.96Å; Q493-L496 VanDerWaalsContact O-N 3.17Å; L496-N498 PolarHBondContact O-N 2.82Å; L496-F499 PolarHBondContact O-N 3.34Å; L496-F499 VanDerWaalsContact O-N 3.16Å; L496-L500 HydrophobicContact CD1-CD1 4.22Å; L496-L500 HydrophobicContact CD1-CG 4.15Å; L496-L500 HydrophobicContact CG-CD1 4.01Å; L496-L500 HydrophobicContact CG-CG 4.37Å; L496-L500 WeakPolarHBondContact O-CB 3.44Å; L496-L500 WeakPolarHBondContact O-CG 3.42Å; L496-L500 PolarHBondContact O-N 2.84Å; L496-L524 HydrophobicContact CD1-CD1 4Å; L496-F527 HydrophobicContact CB-CE1 3.86Å; L496-F527 HydrophobicContact CD1-CD1 3.84Å; L496-F527 HydrophobicContact CD1-CE1 3.89Å; L496-I528 HydrophobicContact CD1-CG2 3.91Å; L496-I533 HydrophobicContact CB-CD1 4.1Å; L496-I533 HydrophobicContact CD2-CB 4.39Å; L496-I533 HydrophobicContact CD2-CD1 4.38Å; L496-I533 HydrophobicContact CD2-CG2 3.8Å; L496-I535 HydrophobicContact CD1-CD1 4.37Å; L496-I535 HydrophobicContact CD1-CG1 4.29Å; L496-I535 HydrophobicContact CD2-CG1 4.07Å; L496-I535 HydrophobicContact CD2-CG2 4.48Å
497	H	80.1	Confident	73.3	Confident	43 Å²	43	29.3 Å²	29.3	20%	0.199	15%	0.154	C	C	.	.	H	α-helix	trans	-57.1	-51.1	177.2	-174	78.7	0	0	0	111.2	Q493 G494 F499 L500 I501	Q493-H497 PolarHBondContact O-N 3.49Å; G494-H497 PolarHBondContact O-N 3.47Å; H497-F499 VanDerWaalsContact C-N 3.29Å; H497-F499 PolarHBondContact O-N 3.42Å; H497-L500 PolarHBondContact O-N 3.35Å; H497-I501 WeakPolarHBondContact CD2-CD1 3.49Å; H497-I501 WeakPolarHBondContact NE2-CD1 3.45Å; H497-I501 WeakPolarHBondContact O-CD1 3.36Å; H497-I501 VanDerWaalsContact O-CG1 3.26Å; H497-I501 WeakPolarHBondContact O-CG1 3.48Å; H497-I501 PolarHBondContact O-N 3.24Å
498	N	80.2	Confident	74.5	Confident	9 Å²	9	28.7 Å²	28.7	5%	0.048	15%	0.148	C	C	.	.	H	α-helix	trans	-59.3	-39.6	175.9	-74.6	-74.6	0	0	0	112.5	L352 L418 G494 L495 L496 I501 L502	L352-N498 PolarHBondContact O-ND2 3.33Å; L418-N498 HydrophobicContact CD2-CB 4.45Å; G494-N498 PolarHBondContact O-N 3.14Å; G494-N498 VanDerWaalsContact O-N 3.07Å; G494-N498 PolarHBondContact O-ND2 3.09Å; L495-N498 PolarHBondContact O-N 3.46Å; L496-N498 PolarHBondContact O-N 2.82Å; N498-I501 PolarHBondContact O-N 3.35Å; N498-L502 WeakPolarHBondContact O-CG 3.15Å; N498-L502 PolarHBondContact O-N 3.37Å; N498-L502 VanDerWaalsContact O-N 3.14Å
499	F	84.8	Confident	75.1	Confident	0 Å²	0	30.6 Å²	30.6	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-67.4	-41	178.8	-167.8	-121.7	0	0	0	112.2	L418 I444 I447 L495 L496 H497 L502 I503 L524 F527	L418-F499 HydrophobicContact CD2-CB 4.23Å; L418-F499 HydrophobicContact CD2-CD2 4.03Å; I444-F499 HydrophobicContact CB-CE2 4.32Å; I444-F499 HydrophobicContact CG1-CE2 4.15Å; I444-F499 HydrophobicContact CG2-CE2 4.09Å; I444-F499 HydrophobicContact CG2-CZ 3.89Å; I447-F499 HydrophobicContact CB-CE2 4.02Å; I447-F499 HydrophobicContact CB-CZ 4.46Å; I447-F499 HydrophobicContact CD1-CD2 4.05Å; I447-F499 HydrophobicContact CD1-CE2 3.91Å; I447-F499 HydrophobicContact CG2-CD2 4.31Å; I447-F499 HydrophobicContact CG2-CE2 3.8Å; I447-F499 HydrophobicContact CG2-CZ 4.05Å; L495-F499 WeakPolarHBondContact O-CB 3.36Å; L495-F499 PolarHBondContact O-N 3.34Å; L496-F499 PolarHBondContact O-N 3.34Å; L496-F499 VanDerWaalsContact O-N 3.16Å; H497-F499 VanDerWaalsContact C-N 3.29Å; H497-F499 PolarHBondContact O-N 3.42Å; F499-L502 WeakPolarHBondContact O-CB 3.43Å; F499-L502 PolarHBondContact O-N 2.9Å; F499-I503 HydrophobicContact CD1-CD1 3.88Å; F499-I503 HydrophobicContact CE1-CD1 3.72Å; F499-I503 HydrophobicContact CZ-CD1 4.28Å; F499-I503 WeakPolarHBondContact O-CG1 3.42Å; F499-I503 PolarHBondContact O-N 3.09Å; F499-L524 HydrophobicContact CD1-CD1 3.94Å; F499-L524 HydrophobicContact CE1-CB 4.45Å; F499-L524 HydrophobicContact CE1-CD1 4.19Å; F499-F527 HydrophobicContact CB-CE2 4.16Å; F499-F527 HydrophobicContact CB-CZ 4.19Å; F499-F527 HydrophobicContact CD1-CB 4.02Å; F499-F527 HydrophobicContact CD1-CD1 4.2Å; F499-F527 AromaticContact CD1-CD2 3.82Å; F499-F527 HydrophobicContact CD1-CD2 3.82Å; F499-F527 HydrophobicContact CD1-CE2 4.31Å; F499-F527 AromaticContact CD1-CG 3.74Å; F499-F527 HydrophobicContact CD1-CG 3.74Å; F499-F527 HydrophobicContact CD2-CD2 4.47Å; F499-F527 HydrophobicContact CE1-CB 3.8Å; F499-F527 HydrophobicContact CE1-CD2 4.06Å; F499-F527 AromaticContact CE1-CG 3.99Å; F499-F527 HydrophobicContact CE1-CG 3.99Å; F499-F527 HydrophobicContact CG-CD2 4.03Å; F499-F527 HydrophobicContact CG-CE2 4.11Å; F499-F527 HydrophobicContact CG-CG 4.36Å; F499-F527 HydrophobicContact CZ-CD2 4.49Å
500	L	82.9	Confident	75.3	Confident	3 Å²	3	30.9 Å²	30.9	2%	0.016	14%	0.144	C	C	.	.	H	α-helix	trans	-64.1	-39.6	175	-73.3	173.3	0	0	0	112	L496 H497 L502 I503 H504 L524 I535 L543 F547	L496-L500 HydrophobicContact CD1-CD1 4.22Å; L496-L500 HydrophobicContact CD1-CG 4.15Å; L496-L500 HydrophobicContact CG-CD1 4.01Å; L496-L500 HydrophobicContact CG-CG 4.37Å; L496-L500 WeakPolarHBondContact O-CB 3.44Å; L496-L500 WeakPolarHBondContact O-CG 3.42Å; L496-L500 PolarHBondContact O-N 2.84Å; H497-L500 PolarHBondContact O-N 3.35Å; L500-L502 VanDerWaalsContact C-N 3.31Å; L500-L502 PolarHBondContact O-N 3.22Å; L500-I503 PolarHBondContact O-N 3.06Å; L500-H504 WeakPolarHBondContact O-CB 3.44Å; L500-H504 PolarHBondContact O-N 2.88Å; L500-L524 HydrophobicContact CD2-CD1 3.73Å; L500-L524 HydrophobicContact CD2-CD2 3.87Å; L500-L524 HydrophobicContact CD2-CG 4.48Å; L500-L524 HydrophobicContact CG-CD1 4.43Å; L500-I535 HydrophobicContact CD1-CG2 3.97Å; L500-L543 HydrophobicContact CB-CD2 3.56Å; L500-F547 HydrophobicContact CD2-CD2 4.48Å
501	I	79.5	Confident	74.7	Confident	10 Å²	10	33.5 Å²	33.5	5%	0.051	17%	0.165	C	C	.	.	H	α-helix	trans	-57.2	-45.3	172.6	-65.9	159.4	0	0	0	111	I358 F425 H497 N498 H504 W505 L543	I358-I501 HydrophobicContact CD1-CB 4.3Å; I358-I501 HydrophobicContact CD1-CD1 3.45Å; I358-I501 VanDerWaalsContact CD1-CD1 3.45Å; I358-I501 HydrophobicContact CD1-CG1 3.51Å; I358-I501 HydrophobicContact CD1-CG2 3.77Å; I358-I501 HydrophobicContact CG1-CD1 4.49Å; F425-I501 HydrophobicContact CD1-CG2 4.25Å; F425-I501 HydrophobicContact CE1-CG2 3.83Å; H497-I501 WeakPolarHBondContact CD2-CD1 3.49Å; H497-I501 WeakPolarHBondContact NE2-CD1 3.45Å; H497-I501 WeakPolarHBondContact O-CD1 3.36Å; H497-I501 VanDerWaalsContact O-CG1 3.26Å; H497-I501 WeakPolarHBondContact O-CG1 3.48Å; H497-I501 PolarHBondContact O-N 3.24Å; N498-I501 PolarHBondContact O-N 3.35Å; I501-H504 PolarHBondContact O-N 3.35Å; I501-W505 WeakPolarHBondContact O-CB 3.42Å; I501-W505 PolarHBondContact O-N 3.05Å; I501-L543 HydrophobicContact CB-CD1 4.26Å; I501-L543 HydrophobicContact CG1-CD1 3.45Å; I501-L543 VanDerWaalsContact CG1-CD1 3.45Å
502	L	82	Confident	74.4	Confident	4 Å²	4	33.9 Å²	33.9	2%	0.021	17%	0.171	C	C	.	.	H	α-helix	trans	-63.5	-42.9	178.6	-70.2	168.9	0	0	0	112.3	L418 A421 F425 I440 I444 N498 F499 L500 Y506	L418-L502 HydrophobicContact CD2-CD1 3.53Å; A421-L502 HydrophobicContact CB-CD1 3.46Å; A421-L502 VanDerWaalsContact CB-CD1 3.46Å; A421-L502 HydrophobicContact CB-CD2 3.44Å; A421-L502 VanDerWaalsContact CB-CD2 3.44Å; A421-L502 HydrophobicContact CB-CG 4.09Å; F425-L502 HydrophobicContact CB-CD2 4.49Å; I440-L502 HydrophobicContact CG2-CD2 4.41Å; I444-L502 HydrophobicContact CD1-CB 4.43Å; N498-L502 WeakPolarHBondContact O-CG 3.15Å; N498-L502 PolarHBondContact O-N 3.37Å; N498-L502 VanDerWaalsContact O-N 3.14Å; F499-L502 WeakPolarHBondContact O-CB 3.43Å; F499-L502 PolarHBondContact O-N 2.9Å; L500-L502 VanDerWaalsContact C-N 3.31Å; L500-L502 PolarHBondContact O-N 3.22Å; L502-Y506 VanDerWaalsContact O-CB 3.29Å; L502-Y506 WeakPolarHBondContact O-CB 3.44Å; L502-Y506 PolarHBondContact O-N 3.19Å
503	I	81.4	Confident	73.6	Confident	1 Å²	1	36.8 Å²	36.8	1%	0.005	18%	0.181	C	C	.	.	H	α-helix	trans	-60.9	-48.7	175.6	-69.6	171.3	0	0	0	110.3	I444 F499 L500 Y506 Y507 L520 L524 F547 L551	I444-I503 HydrophobicContact CD1-CG1 4.38Å; F499-I503 HydrophobicContact CD1-CD1 3.88Å; F499-I503 HydrophobicContact CE1-CD1 3.72Å; F499-I503 HydrophobicContact CZ-CD1 4.28Å; F499-I503 WeakPolarHBondContact O-CG1 3.42Å; F499-I503 PolarHBondContact O-N 3.09Å; L500-I503 PolarHBondContact O-N 3.06Å; I503-Y506 PolarHBondContact O-N 3.32Å; I503-Y507 WeakPolarHBondContact O-CB 3.43Å; I503-Y507 PolarHBondContact O-N 3.37Å; I503-L520 HydrophobicContact CG1-CD2 4.36Å; I503-L520 HydrophobicContact CG2-CB 4.23Å; I503-L520 HydrophobicContact CG2-CD1 4.22Å; I503-L524 HydrophobicContact CD1-CB 3.94Å; I503-L524 HydrophobicContact CD1-CD1 4.02Å; I503-L524 HydrophobicContact CD1-CD2 4.4Å; I503-L524 HydrophobicContact CD1-CG 4.35Å; I503-F547 HydrophobicContact CG2-CD2 4.47Å; I503-F547 HydrophobicContact CG2-CE2 4.38Å; I503-L551 HydrophobicContact CG2-CD2 4.08Å
504	H	76.9	Confident	73.1	Confident	23 Å²	23	35.9 Å²	35.9	11%	0.106	18%	0.183	C	C	.	.	H	α-helix	trans	-62.9	-44.5	-178.9	-176.7	90.1	0	0	0	111.6	L500 I501 Y507 Q508 L543 D546	L500-H504 WeakPolarHBondContact O-CB 3.44Å; L500-H504 PolarHBondContact O-N 2.88Å; I501-H504 PolarHBondContact O-N 3.35Å; H504-Y507 WeakPolarHBondContact O-CB 3.3Å; H504-Y507 PolarHBondContact O-N 3.11Å; H504-Q508 PolarHBondContact NE2-NE2 2.96Å; H504-Q508 WeakPolarHBondContact O-CG 3.22Å; H504-Q508 PolarHBondContact O-N 2.67Å; H504-L543 HydrophobicContact CB-CD2 4.32Å; H504-L543 HydrophobicContact CB-CG 4.35Å; H504-D546 VanDerWaalsContact CE1-CB 3.48Å; H504-D546 WeakPolarHBondContact CE1-CB 3.36Å; H504-D546 IonicContact CE1-OD2 3.97Å; H504-D546 PolarHBondContact CE1-OD2 2.92Å
505	W	75.2	Confident	72.5	Confident	5 Å²	5	39.9 Å²	39.9	2%	0.019	20%	0.201	C	C	.	.	H	α-helix	trans	-62.2	-48	176	175.7	73.2	0	0	0	112.5	F425 I436 I440 I501 Y507 Q508 Y509	F425-W505 HydrophobicContact CD2-CB 4.21Å; F425-W505 AromaticContact CD2-CD1 3.34Å; F425-W505 AromaticContact CD2-CD2 3.7Å; F425-W505 HydrophobicContact CD2-CD2 3.7Å; F425-W505 AromaticContact CD2-CE2 3.65Å; F425-W505 AromaticContact CD2-CG 3.42Å; F425-W505 HydrophobicContact CD2-CG 3.42Å; F425-W505 VanDerWaalsContact CD2-CG 3.42Å; F425-W505 AromaticContact CD2-NE1 3.36Å; F425-W505 HydrophobicContact CE2-CB 4.02Å; F425-W505 AromaticContact CE2-CD1 2.88Å; F425-W505 HydrophobicContact CE2-CD2 4.07Å; F425-W505 AromaticContact CE2-CE2 3.98Å; F425-W505 AromaticContact CE2-CG 3.36Å; F425-W505 HydrophobicContact CE2-CG 3.36Å; F425-W505 AromaticContact CE2-NE1 3.2Å; F425-W505 HydrophobicContact CG-CG 4.3Å; F425-W505 HydrophobicContact CZ-CB 4.27Å; F425-W505 AromaticContact CZ-CD1 3.73Å; F425-W505 HydrophobicContact CZ-CG 4.08Å; I436-W505 HydrophobicContact CG2-CH2 3.91Å; I436-W505 HydrophobicContact CG2-CZ2 4.4Å; I440-W505 HydrophobicContact CB-CE3 4.39Å; I440-W505 HydrophobicContact CB-CZ3 3.9Å; I440-W505 HydrophobicContact CD1-CD2 4.25Å; I440-W505 HydrophobicContact CD1-CE3 3.45Å; I440-W505 VanDerWaalsContact CD1-CE3 3.45Å; I440-W505 HydrophobicContact CD1-CH2 3.58Å; I440-W505 HydrophobicContact CD1-CZ2 4.34Å; I440-W505 HydrophobicContact CD1-CZ3 3.09Å; I440-W505 HydrophobicContact CG1-CE3 4.46Å; I440-W505 HydrophobicContact CG1-CZ3 4.02Å; I440-W505 HydrophobicContact CG2-CE3 3.98Å; I440-W505 HydrophobicContact CG2-CZ3 3.96Å; I501-W505 WeakPolarHBondContact O-CB 3.42Å; I501-W505 PolarHBondContact O-N 3.05Å; W505-Y507 PolarHBondContact O-N 2.84Å; W505-Q508 PolarHBondContact O-N 2.85Å; W505-Y509 AromaticContact CD1-CD2 3.55Å; W505-Y509 AromaticContact CD1-CE2 3.63Å; W505-Y509 HydrophobicContact CD2-CD2 4.22Å; W505-Y509 AromaticContact CE2-CD2 3.47Å; W505-Y509 VanDerWaalsContact CE2-CD2 3.47Å; W505-Y509 AromaticContact CE2-CE2 3.79Å; W505-Y509 AromaticContact CE2-CG 3.92Å; W505-Y509 HydrophobicContact CG-CD2 4.33Å; W505-Y509 HydrophobicContact CZ2-CD1 4.2Å; W505-Y509 AromaticContact CZ2-CD2 3.86Å; W505-Y509 HydrophobicContact CZ2-CD2 3.86Å; W505-Y509 HydrophobicContact CZ2-CE2 4.21Å; W505-Y509 AromaticContact CZ2-CG 3.84Å; W505-Y509 HydrophobicContact CZ2-CG 3.84Å; W505-Y509 AromaticContact NE1-CD2 3.03Å; W505-Y509 AromaticContact NE1-CE2 2.97Å; W505-Y509 AromaticContact NE1-CG 3.92Å; W505-Y509 AromaticContact NE1-CZ 3.82Å; W505-Y509 PolarHBondContact O-N 3.01Å; W505-Y509 VanDerWaalsContact O-N 3.14Å
506	Y	75.8	Confident	72.2	Confident	17 Å²	17	40.5 Å²	40.5	7%	0.067	21%	0.205	C	C	.	.	H	α-helix	trans	-60.9	-38.3	-179.5	179.5	-94.9	0	0	0	110.7	S437 I440 F441 L502 I503 Y509 R510 C516 L520	S437-Y506 VanDerWaalsContact O-CE2 3.23Å; S437-Y506 WeakPolarHBondContact O-CE2 3.29Å; I440-Y506 HydrophobicContact CG2-CD2 4.28Å; F441-Y506 HydrophobicContact CB-CD2 4.35Å; F441-Y506 HydrophobicContact CB-CE2 3.66Å; F441-Y506 AromaticContact CD2-CE1 3.98Å; F441-Y506 HydrophobicContact CD2-CE1 3.98Å; F441-Y506 HydrophobicContact CD2-CE2 4.32Å; F441-Y506 AromaticContact CD2-CZ 3.71Å; F441-Y506 HydrophobicContact CG-CE2 4.32Å; L502-Y506 VanDerWaalsContact O-CB 3.29Å; L502-Y506 WeakPolarHBondContact O-CB 3.44Å; L502-Y506 PolarHBondContact O-N 3.19Å; I503-Y506 PolarHBondContact O-N 3.32Å; Y506-Y509 PolarHBondContact O-N 3.16Å; Y506-R510 HydrophobicContact CE2-CG 4.36Å; Y506-R510 PolarHBondContact O-N 3.3Å; Y506-C516 HydrophobicContact CE1-CB 3.99Å; Y506-C516 PolarHBondContact OH-SG 3.38Å; Y506-C516 VanDerWaalsContact OH-SG 3.39Å; Y506-L520 HydrophobicContact CD1-CD1 3.82Å; Y506-L520 HydrophobicContact CD1-CD2 3.91Å; Y506-L520 HydrophobicContact CD1-CG 4.34Å; Y506-L520 HydrophobicContact CE1-CD1 4.32Å; Y506-L520 HydrophobicContact CE1-CD2 4.4Å
507	Y	71	Confident	72	Confident	46 Å²	46	40.6 Å²	40.6	18%	0.18	21%	0.206	C	C	.	.	H	α-helix	trans	-59.9	-44	172.3	174.3	-93.3	0	0	0	112.8	I503 H504 W505 Y509 W513 F550 L551 K554	I503-Y507 WeakPolarHBondContact O-CB 3.43Å; I503-Y507 PolarHBondContact O-N 3.37Å; H504-Y507 WeakPolarHBondContact O-CB 3.3Å; H504-Y507 PolarHBondContact O-N 3.11Å; W505-Y507 PolarHBondContact O-N 2.84Å; Y507-Y509 PolarHBondContact O-N 2.81Å; Y507-W513 AromaticContact CE2-CD1 3.74Å; Y507-F550 HydrophobicContact CE1-CB 3.74Å; Y507-F550 VanDerWaalsContact CZ-O 3.25Å; Y507-F550 WeakPolarHBondContact OH-CB 3.38Å; Y507-F550 PolarHBondContact OH-O 2.99Å; Y507-L551 HydrophobicContact CD2-CD1 3.36Å; Y507-L551 HydrophobicContact CE2-CD1 3.79Å; Y507-L551 HydrophobicContact CG-CD1 4.2Å; Y507-K554 WeakPolarHBondContact OH-CD 3.46Å; Y507-K554 WeakPolarHBondContact OH-CE 3.42Å; Y507-K554 PolarHBondContact OH-NZ 3.45Å
508	Q	71.1	Confident	72.1	Confident	94 Å²	94	40.1 Å²	40.1	44%	0.439	21%	0.205	S	C	.	.	H	α-helix	trans	-65.1	-34.4	179.1	-72.3	-174.4	-11.5	0	0	113.4	H504 W505	H504-Q508 PolarHBondContact NE2-NE2 2.96Å; H504-Q508 WeakPolarHBondContact O-CG 3.22Å; H504-Q508 PolarHBondContact O-N 2.67Å; W505-Q508 PolarHBondContact O-N 2.85Å
509	Y	67	Low	72.2	Confident	102 Å²	102	42.1 Å²	42.1	40%	0.4	21%	0.214	S	C	.	.	H	α-helix	trans	-92.3	-13.1	-170.2	-94.2	-97.7	0	0	0	116.2	W505 Y506 Y507	W505-Y509 AromaticContact CD1-CD2 3.55Å; W505-Y509 AromaticContact CD1-CE2 3.63Å; W505-Y509 HydrophobicContact CD2-CD2 4.22Å; W505-Y509 AromaticContact CE2-CD2 3.47Å; W505-Y509 VanDerWaalsContact CE2-CD2 3.47Å; W505-Y509 AromaticContact CE2-CE2 3.79Å; W505-Y509 AromaticContact CE2-CG 3.92Å; W505-Y509 HydrophobicContact CG-CD2 4.33Å; W505-Y509 HydrophobicContact CZ2-CD1 4.2Å; W505-Y509 AromaticContact CZ2-CD2 3.86Å; W505-Y509 HydrophobicContact CZ2-CD2 3.86Å; W505-Y509 HydrophobicContact CZ2-CE2 4.21Å; W505-Y509 AromaticContact CZ2-CG 3.84Å; W505-Y509 HydrophobicContact CZ2-CG 3.84Å; W505-Y509 AromaticContact NE1-CD2 3.03Å; W505-Y509 AromaticContact NE1-CE2 2.97Å; W505-Y509 AromaticContact NE1-CG 3.92Å; W505-Y509 AromaticContact NE1-CZ 3.82Å; W505-Y509 PolarHBondContact O-N 3.01Å; W505-Y509 VanDerWaalsContact O-N 3.14Å; Y506-Y509 PolarHBondContact O-N 3.16Å; Y507-Y509 PolarHBondContact O-N 2.81Å
510	R	62.3	Low	72.3	Confident	86 Å²	86	42.2 Å²	42.2	33%	0.325	21%	0.214	S	C	.	.			trans	-134.7	138.5	-173.6	-79.9	-73.5	-165.1	145.6	14.3	114.9	L434 S437 Y506	L434-R510 VanDerWaalsContact CA-NH2 3.31Å; L434-R510 PolarHBondContact O-NH2 3.5Å; S437-R510 PolarHBondContact OG-NE 2.96Å; S437-R510 PolarHBondContact OG-NH2 2.76Å; Y506-R510 HydrophobicContact CE2-CG 4.36Å; Y506-R510 PolarHBondContact O-N 3.3Å
511	C	48.5	Very low	72.5	Confident	129 Å²	129	42.1 Å²	42.1	87%	0.872	21%	0.214	S	C	*	.			trans	-89.9	-14.7	-170.2	-67	0	0	0	0	118.2	W513	C511-W513 PolarHBondContact O-N 3.05Å
512	S	56.4	Low	72.9	Confident	50 Å²	50	44.1 Å²	44.1	35%	0.35	22%	0.221	S	C	.	.			trans	-82.9	66.1	-177.5	68.8	0	0	0	0	111.6	S514 C516	S512-S514 PolarHBondContact O-N 3.43Å; S512-C516 WeakPolarHBondContact O-CB 3.36Å; S512-C516 PolarHBondContact O-N 2.87Å; S512-C516 PolarHBondContact O-SG 3.42Å; S512-C516 PolarHBondContact OG-SG 2.99Å
513	W	58	Low	73.3	Confident	66 Å²	66	44 Å²	44	25%	0.25	22%	0.22	C	C	.	.	H	α-helix	trans	-60.7	-36.2	-167.5	168	89.8	0	0	0	114.4	Y507 C511 G517 K554 L558	Y507-W513 AromaticContact CE2-CD1 3.74Å; C511-W513 PolarHBondContact O-N 3.05Å; W513-G517 PolarHBondContact O-N 3.32Å; W513-K554 HydrophobicContact CH2-CB 4.4Å; W513-K554 WeakPolarHBondContact CH2-O 3.44Å; W513-K554 HydrophobicContact CZ2-CB 3.22Å; W513-K554 HydrophobicContact CZ2-CD 3.82Å; W513-K554 HydrophobicContact CZ2-CG 3.52Å; W513-K554 WeakPolarHBondContact CZ2-O 3.46Å; W513-K554 VanDerWaalsContact NE1-CD 3.35Å; W513-L558 HydrophobicContact CD2-CD1 4.48Å; W513-L558 HydrophobicContact CE3-CD1 3.85Å; W513-L558 HydrophobicContact CE3-CD2 4.35Å; W513-L558 HydrophobicContact CE3-CG 4.36Å; W513-L558 HydrophobicContact CH2-CD1 3.76Å; W513-L558 HydrophobicContact CH2-CD2 4.07Å; W513-L558 HydrophobicContact CH2-CG 3.65Å; W513-L558 HydrophobicContact CZ2-CD1 4.4Å; W513-L558 HydrophobicContact CZ3-CD1 3.46Å; W513-L558 VanDerWaalsContact CZ3-CD1 3.46Å; W513-L558 HydrophobicContact CZ3-CD2 3.48Å; W513-L558 VanDerWaalsContact CZ3-CD2 3.48Å; W513-L558 HydrophobicContact CZ3-CG 3.49Å; W513-L558 VanDerWaalsContact CZ3-CG 3.49Å
514	S	64.4	Low	73.7	Confident	53 Å²	53	43.9 Å²	43.9	37%	0.371	22%	0.22	S	C	.	.	H	α-helix	trans	-66.5	-52.3	-172.1	57.7	0	0	0	0	113.4	S512 I518 L558	S512-S514 PolarHBondContact O-N 3.43Å; S514-I518 WeakPolarHBondContact O-CD1 3.34Å; S514-I518 WeakPolarHBondContact O-CG1 3.44Å; S514-L558 VanDerWaalsContact CA-CD1 3.49Å
515	I	61.1	Low	74.3	Confident	96 Å²	96	42.8 Å²	42.8	49%	0.492	22%	0.215	S	C	.	.	H	α-helix	trans	-76	-41.4	-178	-60.1	170.9	0	0	0	110.5
516	C	75	Confident	74.9	Confident	13 Å²	13	42.7 Å²	42.7	9%	0.088	21%	0.214	C	C	.	.	H	α-helix	trans	-69.9	-42.7	-175.9	-69.9	0	0	0	0	112.1	Y506 S512 I518 E519 L520	Y506-C516 HydrophobicContact CE1-CB 3.99Å; Y506-C516 PolarHBondContact OH-SG 3.38Å; Y506-C516 VanDerWaalsContact OH-SG 3.39Å; S512-C516 WeakPolarHBondContact O-CB 3.36Å; S512-C516 PolarHBondContact O-N 2.87Å; S512-C516 PolarHBondContact O-SG 3.42Å; S512-C516 PolarHBondContact OG-SG 2.99Å; C516-I518 VanDerWaalsContact C-N 3.3Å; C516-I518 PolarHBondContact O-N 2.94Å; C516-E519 PolarHBondContact O-N 3.48Å; C516-L520 VanDerWaalsContact O-CG 3.31Å; C516-L520 WeakPolarHBondContact O-CG 3.36Å; C516-L520 PolarHBondContact O-N 2.98Å
517	G	78.5	Confident	75.4	Confident	3 Å²	3	41.9 Å²	41.9	3%	0.031	21%	0.211	C	C	.	.	H	α-helix	trans	-65.3	-33.2	-177.5	0	0	0	0	0	113	W513 L520 C521 L555	W513-G517 PolarHBondContact O-N 3.32Å; G517-L520 PolarHBondContact O-N 3.04Å; G517-C521 WeakPolarHBondContact O-CB 3.5Å; G517-C521 PolarHBondContact O-N 3.44Å; G517-L555 VanDerWaalsContact O-CD1 3.24Å; G517-L555 WeakPolarHBondContact O-CD1 3.04Å
518	I	82.3	Confident	76.2	Confident	32 Å²	32	39.7 Å²	39.7	16%	0.164	20%	0.203	C	C	.	.	H	α-helix	trans	-59.3	-49.2	174.1	-66.4	166.5	0	0	0	109.7	S514 C516 L520 C521 W522 L555 L560 E564	S514-I518 WeakPolarHBondContact O-CD1 3.34Å; S514-I518 WeakPolarHBondContact O-CG1 3.44Å; C516-I518 VanDerWaalsContact C-N 3.3Å; C516-I518 PolarHBondContact O-N 2.94Å; I518-L520 PolarHBondContact O-N 3.49Å; I518-C521 PolarHBondContact O-N 3.11Å; I518-W522 WeakPolarHBondContact O-CB 3.38Å; I518-W522 PolarHBondContact O-N 3.25Å; I518-L555 HydrophobicContact CG1-CD2 4.07Å; I518-L555 VanDerWaalsContact N-CD2 3.34Å; I518-L560 HydrophobicContact CD1-CB 3.59Å; I518-L560 HydrophobicContact CG1-CB 4.5Å; I518-E564 HydrophobicContact CG2-CG 3.71Å
519	E	83.2	Confident	76.8	Confident	51 Å²	51	37.2 Å²	37.2	24%	0.238	19%	0.191	C	C	.	.	H	α-helix	trans	-65	-35.5	178.4	-71.2	-95.1	174.6	0	0	112.7	F441 R445 C516 S523	F441-E519 HydrophobicContact CE2-CB 4.16Å; F441-E519 HydrophobicContact CZ-CB 4.36Å; F441-E519 HydrophobicContact CZ-CG 4.44Å; R445-E519 IonicContact CZ-OE1 3.36Å; R445-E519 IonicContact CZ-OE2 3.92Å; R445-E519 IonicContact NE-OE1 2.82Å; R445-E519 IonicContact NE-OE2 3.2Å; R445-E519 PolarHBondContact NE-OE2 2.78Å; R445-E519 IonicContact NH2-OE1 3.61Å; R445-E519 PolarHBondContact NH2-OE1 2.98Å; R445-E519 IonicContact NH2-OE2 3.31Å; R445-E519 PolarHBondContact NH2-OE2 2.84Å; C516-E519 PolarHBondContact O-N 3.48Å; E519-S523 VanDerWaalsContact O-CB 3.31Å; E519-S523 WeakPolarHBondContact O-CB 3.46Å; E519-S523 PolarHBondContact O-N 3.18Å; E519-S523 PolarHBondContact O-OG 3.07Å
520	L	86.1	Confident	77.6	Confident	3 Å²	3	34.6 Å²	34.6	2%	0.016	18%	0.181	C	C	.	.	H	α-helix	trans	-64.3	-45.1	174.5	-64.2	174.2	0	0	0	111	I444 I503 Y506 C516 G517 I518 S523 L524 L551	I444-L520 HydrophobicContact CD1-CD2 3.73Å; I444-L520 HydrophobicContact CG2-CD2 3.87Å; I503-L520 HydrophobicContact CG1-CD2 4.36Å; I503-L520 HydrophobicContact CG2-CB 4.23Å; I503-L520 HydrophobicContact CG2-CD1 4.22Å; Y506-L520 HydrophobicContact CD1-CD1 3.82Å; Y506-L520 HydrophobicContact CD1-CD2 3.91Å; Y506-L520 HydrophobicContact CD1-CG 4.34Å; Y506-L520 HydrophobicContact CE1-CD1 4.32Å; Y506-L520 HydrophobicContact CE1-CD2 4.4Å; C516-L520 VanDerWaalsContact O-CG 3.31Å; C516-L520 WeakPolarHBondContact O-CG 3.36Å; C516-L520 PolarHBondContact O-N 2.98Å; G517-L520 PolarHBondContact O-N 3.04Å; I518-L520 PolarHBondContact O-N 3.49Å; L520-S523 PolarHBondContact O-N 2.68Å; L520-L524 WeakPolarHBondContact O-CB 3.39Å; L520-L524 PolarHBondContact O-N 3.31Å; L520-L551 HydrophobicContact CD1-CD1 4.32Å
521	C	86.1	Confident	78.6	Confident	1 Å²	1	31.8 Å²	31.8	1%	0.007	17%	0.171	C	C	.	.	H	α-helix	trans	-65.1	-43.2	178.2	-167.1	0	0	0	0	111.7	G517 I518 L524 T525 L555 E564	G517-C521 WeakPolarHBondContact O-CB 3.5Å; G517-C521 PolarHBondContact O-N 3.44Å; I518-C521 PolarHBondContact O-N 3.11Å; C521-L524 PolarHBondContact O-N 3.2Å; C521-T525 WeakPolarHBondContact O-CB 3.32Å; C521-T525 PolarHBondContact O-N 3.18Å; C521-T525 PolarHBondContact O-OG1 3.05Å; C521-L555 HydrophobicContact CB-CD1 3.85Å; C521-E564 HydrophobicContact CB-CB 4.18Å; C521-E564 PolarHBondContact SG-O 3.05Å
522	W	88.5	Confident	80.1	Confident	52 Å²	52	29.1 Å²	29.1	20%	0.197	15%	0.148	C	C	.	.	H	α-helix	trans	-59.9	-47.5	174.1	175.8	83	0	0	0	111.5	Y452 I518 L524 T525 N526	Y452-W522 HydrophobicContact CD1-CZ2 4.35Å; Y452-W522 HydrophobicContact CD2-CZ2 4.12Å; Y452-W522 AromaticContact CG-CZ2 3.84Å; Y452-W522 HydrophobicContact CG-CZ2 3.84Å; I518-W522 WeakPolarHBondContact O-CB 3.38Å; I518-W522 PolarHBondContact O-N 3.25Å; W522-L524 VanDerWaalsContact C-N 3.33Å; W522-L524 PolarHBondContact O-N 3.16Å; W522-T525 PolarHBondContact O-N 3.44Å; W522-N526 VanDerWaalsContact CD2-ND2 3.32Å; W522-N526 VanDerWaalsContact CZ2-ND2 3.29Å; W522-N526 WeakPolarHBondContact CZ2-ND2 3.47Å; W522-N526 PolarHBondContact NE1-ND2 3.26Å; W522-N526 PolarHBondContact O-N 3.31Å; W522-N526 PolarHBondContact O-ND2 2.99Å
523	S	90	Very high	81.1	Confident	0 Å²	0	27 Å²	27	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-63	-40.6	179.6	-56	0	0	0	0	111.6	E519 L520 F527	E519-S523 VanDerWaalsContact O-CB 3.31Å; E519-S523 WeakPolarHBondContact O-CB 3.46Å; E519-S523 PolarHBondContact O-N 3.18Å; E519-S523 PolarHBondContact O-OG 3.07Å; L520-S523 PolarHBondContact O-N 2.68Å; S523-F527 WeakPolarHBondContact O-CB 3.38Å; S523-F527 PolarHBondContact O-N 3.42Å
524	L	90.3	Very high	82.1	Confident	0 Å²	0	24.1 Å²	24.1	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-64.5	-44.9	175	-174.9	62.5	0	0	0	112.6	L496 F499 L500 I503 L520 C521 W522 N526 F527 I528 I535 F547 L568	L496-L524 HydrophobicContact CD1-CD1 4Å; F499-L524 HydrophobicContact CD1-CD1 3.94Å; F499-L524 HydrophobicContact CE1-CB 4.45Å; F499-L524 HydrophobicContact CE1-CD1 4.19Å; L500-L524 HydrophobicContact CD2-CD1 3.73Å; L500-L524 HydrophobicContact CD2-CD2 3.87Å; L500-L524 HydrophobicContact CD2-CG 4.48Å; L500-L524 HydrophobicContact CG-CD1 4.43Å; I503-L524 HydrophobicContact CD1-CB 3.94Å; I503-L524 HydrophobicContact CD1-CD1 4.02Å; I503-L524 HydrophobicContact CD1-CD2 4.4Å; I503-L524 HydrophobicContact CD1-CG 4.35Å; L520-L524 WeakPolarHBondContact O-CB 3.39Å; L520-L524 PolarHBondContact O-N 3.31Å; C521-L524 PolarHBondContact O-N 3.2Å; W522-L524 VanDerWaalsContact C-N 3.33Å; W522-L524 PolarHBondContact O-N 3.16Å; L524-N526 VanDerWaalsContact C-N 3.31Å; L524-N526 PolarHBondContact O-N 3.16Å; L524-F527 WeakPolarHBondContact O-CB 3.36Å; L524-F527 PolarHBondContact O-N 3.49Å; L524-F527 VanDerWaalsContact O-N 3.15Å; L524-I528 HydrophobicContact CD1-CG2 4.36Å; L524-I528 WeakPolarHBondContact O-CG1 3.34Å; L524-I528 PolarHBondContact O-N 3.18Å; L524-I535 HydrophobicContact CD1-CD1 3.81Å; L524-I535 HydrophobicContact CD2-CD1 3.69Å; L524-I535 HydrophobicContact CG-CD1 3.77Å; L524-F547 HydrophobicContact CD2-CD2 4.48Å; L524-F547 HydrophobicContact CD2-CE1 4.15Å; L524-F547 HydrophobicContact CD2-CE2 3.48Å; L524-F547 VanDerWaalsContact CD2-CE2 3.48Å; L524-F547 HydrophobicContact CD2-CZ 3.31Å; L524-L568 HydrophobicContact CD2-CD1 4.21Å; L524-L568 HydrophobicContact CD2-CD2 4.29Å; L524-L568 HydrophobicContact CG-CD1 4.12Å
525	T	88.8	Confident	82.7	Confident	0 Å²	0	21.6 Å²	21.6	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-59.3	-44.4	178.9	-53.4	0	0	0	0	111.2	C521 W522 I528 Q529 F567 L568 T571	C521-T525 WeakPolarHBondContact O-CB 3.32Å; C521-T525 PolarHBondContact O-N 3.18Å; C521-T525 PolarHBondContact O-OG1 3.05Å; W522-T525 PolarHBondContact O-N 3.44Å; T525-I528 WeakPolarHBondContact O-CG1 3.12Å; T525-Q529 VanDerWaalsContact O-CB 3.29Å; T525-Q529 WeakPolarHBondContact O-CB 3.25Å; T525-Q529 PolarHBondContact O-N 3.36Å; T525-Q529 VanDerWaalsContact O-N 3.16Å; T525-F567 HydrophobicContact CG2-CD1 3.51Å; T525-F567 HydrophobicContact CG2-CE1 3.59Å; T525-F567 HydrophobicContact CG2-CG 4.08Å; T525-F567 HydrophobicContact CG2-CZ 4.22Å; T525-L568 WeakPolarHBondContact OG1-CA 3.5Å; T525-L568 WeakPolarHBondContact OG1-CB 3.13Å; T525-L568 WeakPolarHBondContact OG1-CD1 3.3Å; T525-T571 HydrophobicContact CG2-CG2 4.24Å
526	N	87.6	Confident	83.2	Confident	3 Å²	3	17 Å²	17	2%	0.016	8%	0.082	C	C	.	.	H	α-helix	trans	-68.6	-37.3	176.6	-66.9	-52.5	0	0	0	112.2	C451 W522 L524 Q529 Y530	C451-N526 HydrophobicContact CB-CB 3.95Å; C451-N526 WeakPolarHBondContact CB-O 3.37Å; W522-N526 VanDerWaalsContact CD2-ND2 3.32Å; W522-N526 VanDerWaalsContact CZ2-ND2 3.29Å; W522-N526 WeakPolarHBondContact CZ2-ND2 3.47Å; W522-N526 PolarHBondContact NE1-ND2 3.26Å; W522-N526 PolarHBondContact O-N 3.31Å; W522-N526 PolarHBondContact O-ND2 2.99Å; L524-N526 VanDerWaalsContact C-N 3.31Å; L524-N526 PolarHBondContact O-N 3.16Å; N526-Q529 PolarHBondContact O-N 2.99Å; N526-Y530 WeakPolarHBondContact O-CB 3.41Å; N526-Y530 PolarHBondContact O-N 3.26Å
527	F	88.2	Confident	82.7	Confident	0 Å²	0	19.8 Å²	19.8	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-59.6	-50.2	177.5	-174.7	-81.6	0	0	0	112	I414 I447 L495 L496 F499 S523 L524 Q529 Y530 F531	I414-F527 HydrophobicContact CG2-CE2 4.35Å; I447-F527 HydrophobicContact CG2-CD2 3.56Å; I447-F527 HydrophobicContact CG2-CE2 4.03Å; L495-F527 HydrophobicContact CB-CZ 3.93Å; L496-F527 HydrophobicContact CB-CE1 3.86Å; L496-F527 HydrophobicContact CD1-CD1 3.84Å; L496-F527 HydrophobicContact CD1-CE1 3.89Å; F499-F527 HydrophobicContact CB-CE2 4.16Å; F499-F527 HydrophobicContact CB-CZ 4.19Å; F499-F527 HydrophobicContact CD1-CB 4.02Å; F499-F527 HydrophobicContact CD1-CD1 4.2Å; F499-F527 AromaticContact CD1-CD2 3.82Å; F499-F527 HydrophobicContact CD1-CD2 3.82Å; F499-F527 HydrophobicContact CD1-CE2 4.31Å; F499-F527 AromaticContact CD1-CG 3.74Å; F499-F527 HydrophobicContact CD1-CG 3.74Å; F499-F527 HydrophobicContact CD2-CD2 4.47Å; F499-F527 HydrophobicContact CE1-CB 3.8Å; F499-F527 HydrophobicContact CE1-CD2 4.06Å; F499-F527 AromaticContact CE1-CG 3.99Å; F499-F527 HydrophobicContact CE1-CG 3.99Å; F499-F527 HydrophobicContact CG-CD2 4.03Å; F499-F527 HydrophobicContact CG-CE2 4.11Å; F499-F527 HydrophobicContact CG-CG 4.36Å; F499-F527 HydrophobicContact CZ-CD2 4.49Å; S523-F527 WeakPolarHBondContact O-CB 3.38Å; S523-F527 PolarHBondContact O-N 3.42Å; L524-F527 WeakPolarHBondContact O-CB 3.36Å; L524-F527 PolarHBondContact O-N 3.49Å; L524-F527 VanDerWaalsContact O-N 3.15Å; F527-Q529 VanDerWaalsContact C-N 3.27Å; F527-Q529 PolarHBondContact O-N 2.88Å; F527-Y530 PolarHBondContact O-N 2.84Å; F527-F531 AromaticContact CD1-CD2 3.9Å; F527-F531 HydrophobicContact CD1-CD2 3.9Å; F527-F531 HydrophobicContact CD1-CE2 4.44Å; F527-F531 HydrophobicContact CD2-CD2 4.21Å; F527-F531 AromaticContact CD2-CE2 4Å; F527-F531 HydrophobicContact CD2-CE2 4Å; F527-F531 AromaticContact CE1-CD2 3.52Å; F527-F531 HydrophobicContact CE1-CD2 3.52Å; F527-F531 AromaticContact CE1-CE2 3.92Å; F527-F531 HydrophobicContact CE1-CE2 3.92Å; F527-F531 HydrophobicContact CE1-CG 4.5Å; F527-F531 AromaticContact CE2-CD2 3.91Å; F527-F531 HydrophobicContact CE2-CD2 3.91Å; F527-F531 AromaticContact CE2-CE2 3.46Å; F527-F531 HydrophobicContact CE2-CE2 3.46Å; F527-F531 VanDerWaalsContact CE2-CE2 3.46Å; F527-F531 HydrophobicContact CG-CD2 4.22Å; F527-F531 HydrophobicContact CG-CE2 4.47Å; F527-F531 AromaticContact CZ-CD2 3.54Å; F527-F531 HydrophobicContact CZ-CD2 3.54Å; F527-F531 AromaticContact CZ-CE2 3.41Å; F527-F531 HydrophobicContact CZ-CE2 3.41Å; F527-F531 VanDerWaalsContact CZ-CE2 3.41Å; F527-F531 HydrophobicContact CZ-CZ 4.45Å; F527-F531 WeakPolarHBondContact O-CD2 3.45Å; F527-F531 PolarHBondContact O-N 3.46Å; F527-F531 VanDerWaalsContact O-N 3.09Å
528	I	86.6	Confident	81.7	Confident	0 Å²	0	21.6 Å²	21.6	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-65.5	-34	179.6	60.8	171.4	0	0	0	112.6	L496 L524 T525 N532 I533 I535 L568 T571 N572 I575	L496-I528 HydrophobicContact CD1-CG2 3.91Å; L524-I528 HydrophobicContact CD1-CG2 4.36Å; L524-I528 WeakPolarHBondContact O-CG1 3.34Å; L524-I528 PolarHBondContact O-N 3.18Å; T525-I528 WeakPolarHBondContact O-CG1 3.12Å; I528-N532 CarbonylContact O-C 3.47Å; I528-N532 VanDerWaalsContact O-CA 3.23Å; I528-N532 WeakPolarHBondContact O-CA 3.27Å; I528-N532 PolarHBondContact O-N 3.26Å; I528-I533 WeakPolarHBondContact CB-O 3.34Å; I528-I533 PolarHBondContact O-N 3.36Å; I528-I535 HydrophobicContact CG2-CD1 3.58Å; I528-I535 HydrophobicContact CG2-CG1 3.48Å; I528-I535 VanDerWaalsContact CG2-CG1 3.48Å; I528-L568 HydrophobicContact CD1-CD1 3.66Å; I528-T571 HydrophobicContact CD1-CG2 4.02Å; I528-T571 HydrophobicContact CG1-CG2 4.16Å; I528-N572 WeakPolarHBondContact CD1-ND2 3.37Å; I528-I575 HydrophobicContact CB-CD1 4.49Å; I528-I575 HydrophobicContact CG1-CD1 4.49Å
529	Q	84.8	Confident	80.3	Confident	41 Å²	41	28.4 Å²	28.4	19%	0.192	13%	0.132	C	C	.	.	H	α-helix	trans	-70.3	-38.1	177.6	-172.3	168.3	18.8	0	0	111.5	H455 T525 N526 F527 T571	H455-Q529 VanDerWaalsContact CD2-CD 3.49Å; H455-Q529 PolarHBondContact CD2-NE2 3.29Å; H455-Q529 PolarHBondContact CE1-NE2 2.83Å; H455-Q529 PolarHBondContact NE2-NE2 3.47Å; T525-Q529 VanDerWaalsContact O-CB 3.29Å; T525-Q529 WeakPolarHBondContact O-CB 3.25Å; T525-Q529 PolarHBondContact O-N 3.36Å; T525-Q529 VanDerWaalsContact O-N 3.16Å; N526-Q529 PolarHBondContact O-N 2.99Å; F527-Q529 VanDerWaalsContact C-N 3.27Å; F527-Q529 PolarHBondContact O-N 2.88Å; Q529-T571 HydrophobicContact CB-CG2 4Å; Q529-T571 HydrophobicContact CG-CG2 4.35Å
530	Y	83.4	Confident	78.9	Confident	47 Å²	47	31.1 Å²	31.1	18%	0.184	16%	0.157	C	C	.	.	H	α-helix	trans	-64.3	-46.3	176.2	178.9	-89.3	0	0	0	112	I414 C451 H454 N526 F527	I414-Y530 HydrophobicContact CD1-CE1 4.17Å; C451-Y530 HydrophobicContact CB-CD2 4.27Å; C451-Y530 HydrophobicContact CB-CG 4.08Å; H454-Y530 HydrophobicContact CB-CD2 3.61Å; H454-Y530 HydrophobicContact CB-CE2 3.45Å; H454-Y530 VanDerWaalsContact CB-CE2 3.45Å; H454-Y530 AromaticContact CD2-CE2 3.78Å; H454-Y530 AromaticContact CG-CD2 3.77Å; H454-Y530 AromaticContact CG-CE2 3.36Å; H454-Y530 AromaticContact ND1-CD2 3.83Å; H454-Y530 AromaticContact ND1-CE2 3.68Å; N526-Y530 WeakPolarHBondContact O-CB 3.41Å; N526-Y530 PolarHBondContact O-N 3.26Å; F527-Y530 PolarHBondContact O-N 2.84Å
531	F	82.7	Confident	78.1	Confident	28 Å²	28	32.5 Å²	32.5	12%	0.123	16%	0.164	C	C	.	.	H	α-helix	trans	-88	-3.7	179.9	-72	-71.3	0	0	0	114.1	F411 I414 L495 F527 I533	F411-F531 AromaticContact CD2-CE1 4Å; F411-F531 HydrophobicContact CD2-CE1 4Å; F411-F531 HydrophobicContact CD2-CZ 4.32Å; F411-F531 AromaticContact CE2-CE1 3.92Å; F411-F531 HydrophobicContact CE2-CE1 3.92Å; F411-F531 HydrophobicContact CE2-CZ 4.44Å; I414-F531 HydrophobicContact CD1-CE2 4.37Å; I414-F531 HydrophobicContact CD1-CZ 4.22Å; I414-F531 HydrophobicContact CG2-CZ 4.46Å; L495-F531 HydrophobicContact CD1-CE1 4.08Å; L495-F531 HydrophobicContact CD1-CZ 3.91Å; F527-F531 AromaticContact CD1-CD2 3.9Å; F527-F531 HydrophobicContact CD1-CD2 3.9Å; F527-F531 HydrophobicContact CD1-CE2 4.44Å; F527-F531 HydrophobicContact CD2-CD2 4.21Å; F527-F531 AromaticContact CD2-CE2 4Å; F527-F531 HydrophobicContact CD2-CE2 4Å; F527-F531 AromaticContact CE1-CD2 3.52Å; F527-F531 HydrophobicContact CE1-CD2 3.52Å; F527-F531 AromaticContact CE1-CE2 3.92Å; F527-F531 HydrophobicContact CE1-CE2 3.92Å; F527-F531 HydrophobicContact CE1-CG 4.5Å; F527-F531 AromaticContact CE2-CD2 3.91Å; F527-F531 HydrophobicContact CE2-CD2 3.91Å; F527-F531 AromaticContact CE2-CE2 3.46Å; F527-F531 HydrophobicContact CE2-CE2 3.46Å; F527-F531 VanDerWaalsContact CE2-CE2 3.46Å; F527-F531 HydrophobicContact CG-CD2 4.22Å; F527-F531 HydrophobicContact CG-CE2 4.47Å; F527-F531 AromaticContact CZ-CD2 3.54Å; F527-F531 HydrophobicContact CZ-CD2 3.54Å; F527-F531 AromaticContact CZ-CE2 3.41Å; F527-F531 HydrophobicContact CZ-CE2 3.41Å; F527-F531 VanDerWaalsContact CZ-CE2 3.41Å; F527-F531 HydrophobicContact CZ-CZ 4.45Å; F527-F531 WeakPolarHBondContact O-CD2 3.45Å; F527-F531 PolarHBondContact O-N 3.46Å; F527-F531 VanDerWaalsContact O-N 3.09Å; F531-I533 HydrophobicContact CB-CD1 3.59Å; F531-I533 HydrophobicContact CB-CG1 3.62Å; F531-I533 HydrophobicContact CG-CD1 4.39Å; F531-I533 PolarHBondContact O-N 3.21Å
532	N	79.8	Confident	77.4	Confident	73 Å²	73	37.6 Å²	37.6	39%	0.39	19%	0.188	S	C	.	.	T	Hydrogen-bonded Turn	trans	51.9	49.4	-174.7	-167.2	54.7	0	0	0	113.4	I528 N579	I528-N532 CarbonylContact O-C 3.47Å; I528-N532 VanDerWaalsContact O-CA 3.23Å; I528-N532 WeakPolarHBondContact O-CA 3.27Å; I528-N532 PolarHBondContact O-N 3.26Å; N532-N579 PolarHBondContact ND2-OD1 2.88Å
533	I	78.2	Confident	76.6	Confident	5 Å²	5	36.1 Å²	36.1	3%	0.026	18%	0.183	C	C	.	.			trans	-113.8	134.7	-178.1	-45	170.9	0	0	0	111	S492 Q493 L496 I528 F531	S492-I533 VanDerWaalsContact CB-CD1 3.47Å; S492-I533 WeakPolarHBondContact O-CD1 3.12Å; S492-I533 VanDerWaalsContact OG-CD1 3.26Å; S492-I533 WeakPolarHBondContact OG-CD1 3.49Å; Q493-I533 HydrophobicContact CG-CG2 4.36Å; L496-I533 HydrophobicContact CB-CD1 4.1Å; L496-I533 HydrophobicContact CD2-CB 4.39Å; L496-I533 HydrophobicContact CD2-CD1 4.38Å; L496-I533 HydrophobicContact CD2-CG2 3.8Å; I528-I533 WeakPolarHBondContact CB-O 3.34Å; I528-I533 PolarHBondContact O-N 3.36Å; F531-I533 HydrophobicContact CB-CD1 3.59Å; F531-I533 HydrophobicContact CB-CG1 3.62Å; F531-I533 HydrophobicContact CG-CD1 4.39Å; F531-I533 PolarHBondContact O-N 3.21Å
534	S	79	Confident	75.9	Confident	6 Å²	6	36.1 Å²	36.1	4%	0.042	18%	0.184	C	C	.	.			trans	-84.7	119.5	166.7	7	0	0	0	0	110	E537	S534-E537 PolarHBondContact OG-OE1 3.38Å; S534-E537 PolarHBondContact OG-OE2 3.41Å
535	I	76.9	Confident	75.3	Confident	0 Å²	0	38.6 Å²	38.6	0%	0	20%	0.197	C	C	.	.	G	3₁₀ helix	trans	-71.2	-35.8	177.1	-46.9	-177.7	0	0	0	110.9	L496 L500 L524 I528 E537 L544 L568 N572	L496-I535 HydrophobicContact CD1-CD1 4.37Å; L496-I535 HydrophobicContact CD1-CG1 4.29Å; L496-I535 HydrophobicContact CD2-CG1 4.07Å; L496-I535 HydrophobicContact CD2-CG2 4.48Å; L500-I535 HydrophobicContact CD1-CG2 3.97Å; L524-I535 HydrophobicContact CD1-CD1 3.81Å; L524-I535 HydrophobicContact CD2-CD1 3.69Å; L524-I535 HydrophobicContact CG-CD1 3.77Å; I528-I535 HydrophobicContact CG2-CD1 3.58Å; I528-I535 HydrophobicContact CG2-CG1 3.48Å; I528-I535 VanDerWaalsContact CG2-CG1 3.48Å; I535-E537 VanDerWaalsContact C-N 3.27Å; I535-E537 PolarHBondContact O-N 2.97Å; I535-L544 HydrophobicContact CG2-CD1 3.5Å; I535-L544 VanDerWaalsContact CG2-CD1 3.5Å; I535-L544 HydrophobicContact CG2-CD2 4.14Å; I535-L544 HydrophobicContact CG2-CG 4.46Å; I535-L544 WeakPolarHBondContact O-CD2 3.37Å; I535-L568 HydrophobicContact CD1-CD1 4.48Å; I535-N572 PolarHBondContact N-OD1 3.29Å
536	F	71.2	Confident	74.6	Confident	0 Å²	0	40.5 Å²	40.5	0%	0	21%	0.207	C	C	.	.	G	3₁₀ helix	trans	-84.3	6.2	-170	-56.6	-61.4	0	0	0	114.5	L544 I548 L552 L569 N572 Y598 W599 I602	F536-L544 HydrophobicContact CD1-CD1 4.16Å; F536-L544 HydrophobicContact CD1-CD2 4.11Å; F536-L544 HydrophobicContact CD1-CG 4.43Å; F536-L544 HydrophobicContact CE1-CD1 3.91Å; F536-I548 HydrophobicContact CD1-CD1 4.21Å; F536-I548 HydrophobicContact CE1-CD1 3.87Å; F536-I548 HydrophobicContact CE1-CG1 4Å; F536-L552 HydrophobicContact CZ-CD1 4.44Å; F536-L569 HydrophobicContact CE2-CD2 3.89Å; F536-L569 HydrophobicContact CZ-CD2 4.15Å; F536-N572 HydrophobicContact CD2-CB 3.9Å; F536-N572 HydrophobicContact CE2-CB 4.09Å; F536-Y598 HydrophobicContact CD1-CG 4.5Å; F536-W599 HydrophobicContact CB-CD2 4.44Å; F536-W599 HydrophobicContact CB-CZ2 4.06Å; F536-W599 AromaticContact CD2-CH2 3.59Å; F536-W599 HydrophobicContact CD2-CH2 3.59Å; F536-W599 AromaticContact CD2-CZ2 3.56Å; F536-W599 HydrophobicContact CD2-CZ2 3.56Å; F536-W599 HydrophobicContact CD2-CZ3 4.16Å; F536-W599 HydrophobicContact CE2-CH2 4.09Å; F536-W599 HydrophobicContact CE2-CZ2 4.48Å; F536-W599 HydrophobicContact CE2-CZ3 4.48Å; F536-W599 HydrophobicContact CG-CZ2 4.22Å; F536-I602 HydrophobicContact CD1-CD1 3.74Å; F536-I602 HydrophobicContact CD2-CD1 4.09Å; F536-I602 HydrophobicContact CE1-CD1 3.54Å; F536-I602 HydrophobicContact CE2-CD1 3.89Å; F536-I602 HydrophobicContact CG-CD1 4.03Å; F536-I602 HydrophobicContact CZ-CD1 3.61Å
537	E	63.9	Low	74.3	Confident	70 Å²	70	40.8 Å²	40.8	33%	0.327	21%	0.208	S	C	.	.	G	3₁₀ helix	trans	-90.8	-14.2	173.3	-75.2	176.6	177.4	0	0	113.1	S534 I535 M576	S534-E537 PolarHBondContact OG-OE1 3.38Å; S534-E537 PolarHBondContact OG-OE2 3.41Å; I535-E537 VanDerWaalsContact C-N 3.27Å; I535-E537 PolarHBondContact O-N 2.97Å; E537-M576 HydrophobicContact CG-SD 4.24Å; E537-M576 VanDerWaalsContact OE1-CG 3.27Å; E537-M576 WeakPolarHBondContact OE1-CG 3.36Å
538	E	58.2	Low	73.7	Confident	41 Å²	41	40.8 Å²	40.8	19%	0.192	21%	0.208	C	C	.	.	S	Bend	trans	-67	148.8	-177.5	-74.3	-173.7	177	0	0	112.9
539	Q	53.6	Low	73.2	Confident	175 Å²	175	43.5 Å²	43.5	82%	0.818	22%	0.223	S	C	*	.	S	Bend	trans	-55.6	151.7	169.2	-67.3	-172.9	5.4	0	0	110.4	N541	Q539-N541 PolarHBondContact O-N 3.43Å
540	S	53.9	Low	72.6	Confident	109 Å²	109	46.2 Å²	46.2	76%	0.762	23%	0.234	S	C	*	.			trans	-42.4	103.8	-174.4	57.2	0	0	0	0	113.2	Y598	S540-Y598 WeakPolarHBondContact CA-OH 3.12Å
541	N	67.9	Low	72.4	Confident	32 Å²	32	44.1 Å²	44.1	17%	0.171	23%	0.226	C	C	.	.			trans	-108.2	121.6	178.3	-171.7	-15.7	0	0	0	108.5	Q539 L543 L544 N545 Y598	Q539-N541 PolarHBondContact O-N 3.43Å; N541-L543 PolarHBondContact O-N 3.48Å; N541-L543 VanDerWaalsContact OD1-CB 3.25Å; N541-L543 WeakPolarHBondContact OD1-CB 3.42Å; N541-L543 PolarHBondContact OD1-N 2.9Å; N541-L544 HydrophobicContact CB-CB 4.09Å; N541-L544 PolarHBondContact O-N 3.33Å; N541-L544 VanDerWaalsContact O-N 3.11Å; N541-N545 PolarHBondContact O-N 2.9Å; N541-Y598 PolarHBondContact N-OH 3.24Å; N541-Y598 PolarHBondContact O-OH 2.82Å
542	Q	71.6	Confident	72.3	Confident	108 Å²	108	43.3 Å²	43.3	51%	0.505	22%	0.223	S	C	.	.	H	α-helix	trans	-56.2	-36.8	177.2	-178.4	172.5	-21.6	0	0	111.1	D360 L544 N545 D546	D360-Q542 PolarHBondContact OD2-NE2 3.27Å; Q542-L544 VanDerWaalsContact C-N 3.34Å; Q542-L544 PolarHBondContact O-N 2.75Å; Q542-N545 WeakPolarHBondContact O-CB 3.29Å; Q542-N545 PolarHBondContact O-N 3.4Å; Q542-D546 PolarHBondContact O-N 3.39Å
543	L	72.4	Confident	72.1	Confident	20 Å²	20	41.5 Å²	41.5	11%	0.105	21%	0.213	C	C	.	.	H	α-helix	trans	-64	-39.5	178.3	-162.2	156	0	0	0	112	L500 I501 H504 N541 D546 F547	L500-L543 HydrophobicContact CB-CD2 3.56Å; I501-L543 HydrophobicContact CB-CD1 4.26Å; I501-L543 HydrophobicContact CG1-CD1 3.45Å; I501-L543 VanDerWaalsContact CG1-CD1 3.45Å; H504-L543 HydrophobicContact CB-CD2 4.32Å; H504-L543 HydrophobicContact CB-CG 4.35Å; N541-L543 PolarHBondContact O-N 3.48Å; N541-L543 VanDerWaalsContact OD1-CB 3.25Å; N541-L543 WeakPolarHBondContact OD1-CB 3.42Å; N541-L543 PolarHBondContact OD1-N 2.9Å; L543-D546 PolarHBondContact O-N 3.46Å; L543-F547 WeakPolarHBondContact O-CB 3.22Å; L543-F547 PolarHBondContact O-N 3.45Å
544	L	75.2	Confident	72.1	Confident	1 Å²	1	45.7 Å²	45.7	1%	0.005	23%	0.231	C	C	.	.	H	α-helix	trans	-71.3	-36.8	176.6	-173.6	58.1	0	0	0	111.8	I535 F536 N541 Q542 F547 I548 Y598	I535-L544 HydrophobicContact CG2-CD1 3.5Å; I535-L544 VanDerWaalsContact CG2-CD1 3.5Å; I535-L544 HydrophobicContact CG2-CD2 4.14Å; I535-L544 HydrophobicContact CG2-CG 4.46Å; I535-L544 WeakPolarHBondContact O-CD2 3.37Å; F536-L544 HydrophobicContact CD1-CD1 4.16Å; F536-L544 HydrophobicContact CD1-CD2 4.11Å; F536-L544 HydrophobicContact CD1-CG 4.43Å; F536-L544 HydrophobicContact CE1-CD1 3.91Å; N541-L544 HydrophobicContact CB-CB 4.09Å; N541-L544 PolarHBondContact O-N 3.33Å; N541-L544 VanDerWaalsContact O-N 3.11Å; Q542-L544 VanDerWaalsContact C-N 3.34Å; Q542-L544 PolarHBondContact O-N 2.75Å; L544-F547 HydrophobicContact CD1-CD1 4.24Å; L544-F547 PolarHBondContact O-N 3.25Å; L544-I548 HydrophobicContact CD1-CD1 4.49Å; L544-I548 HydrophobicContact CG-CD1 4.2Å; L544-I548 VanDerWaalsContact O-CG1 3.29Å; L544-I548 WeakPolarHBondContact O-CG1 3.49Å; L544-I548 PolarHBondContact O-N 3.33Å; L544-Y598 HydrophobicContact CB-CE1 4.25Å; L544-Y598 HydrophobicContact CD2-CD1 4.22Å; L544-Y598 HydrophobicContact CD2-CD2 3.8Å; L544-Y598 HydrophobicContact CD2-CE1 4.01Å; L544-Y598 HydrophobicContact CD2-CE2 3.61Å; L544-Y598 HydrophobicContact CD2-CG 4.1Å; L544-Y598 HydrophobicContact CG-CD1 4.28Å; L544-Y598 HydrophobicContact CG-CE1 3.93Å; L544-Y598 HydrophobicContact CG-CE2 4.41Å
545	N	77.2	Confident	72.3	Confident	52 Å²	52	45.5 Å²	45.5	28%	0.278	23%	0.229	S	C	.	.	H	α-helix	trans	-59	-49	170.8	-83.2	-48.8	0	0	0	111.1	N541 Q542 F547 I548 D549 Y598 K601	N541-N545 PolarHBondContact O-N 2.9Å; Q542-N545 WeakPolarHBondContact O-CB 3.29Å; Q542-N545 PolarHBondContact O-N 3.4Å; N545-F547 VanDerWaalsContact C-N 3.32Å; N545-F547 PolarHBondContact O-N 2.79Å; N545-I548 PolarHBondContact O-N 2.96Å; N545-D549 WeakPolarHBondContact O-CB 3.34Å; N545-D549 VanDerWaalsContact O-CG 3.29Å; N545-D549 PolarHBondContact O-N 3.47Å; N545-Y598 WeakPolarHBondContact OD1-CE1 3.42Å; N545-K601 PolarHBondContact OD1-NZ 3.3Å
546	D	75.3	Confident	72.5	Confident	40 Å²	40	45.7 Å²	45.7	21%	0.214	23%	0.23	C	C	.	.	H	α-helix	trans	-63.4	-38.6	178	-72.1	-17.1	0	0	0	112	H504 Q542 L543 F550	H504-D546 VanDerWaalsContact CE1-CB 3.48Å; H504-D546 WeakPolarHBondContact CE1-CB 3.36Å; H504-D546 IonicContact CE1-OD2 3.97Å; H504-D546 PolarHBondContact CE1-OD2 2.92Å; Q542-D546 PolarHBondContact O-N 3.39Å; L543-D546 PolarHBondContact O-N 3.46Å; D546-F550 HydrophobicContact CB-CD2 3.88Å; D546-F550 HydrophobicContact CB-CE2 4.32Å; D546-F550 WeakPolarHBondContact O-CA 3.46Å; D546-F550 WeakPolarHBondContact O-CB 3.42Å; D546-F550 WeakPolarHBondContact O-CD2 3.09Å; D546-F550 PolarHBondContact O-N 3.48Å; D546-F550 WeakPolarHBondContact OD1-CE2 3.38Å
547	F	79.7	Confident	72.9	Confident	8 Å²	8	49.2 Å²	49.2	4%	0.035	26%	0.255	C	S	.	.	I	π-helix	trans	-60.2	-47.6	174.5	174.7	-90.3	0	0	0	111.4	L500 I503 L524 L543 L544 N545 L551 L552 L568	L500-F547 HydrophobicContact CD2-CD2 4.48Å; I503-F547 HydrophobicContact CG2-CD2 4.47Å; I503-F547 HydrophobicContact CG2-CE2 4.38Å; L524-F547 HydrophobicContact CD2-CD2 4.48Å; L524-F547 HydrophobicContact CD2-CE1 4.15Å; L524-F547 HydrophobicContact CD2-CE2 3.48Å; L524-F547 VanDerWaalsContact CD2-CE2 3.48Å; L524-F547 HydrophobicContact CD2-CZ 3.31Å; L543-F547 WeakPolarHBondContact O-CB 3.22Å; L543-F547 PolarHBondContact O-N 3.45Å; L544-F547 HydrophobicContact CD1-CD1 4.24Å; L544-F547 PolarHBondContact O-N 3.25Å; N545-F547 VanDerWaalsContact C-N 3.32Å; N545-F547 PolarHBondContact O-N 2.79Å; F547-L551 HydrophobicContact CD2-CB 4.21Å; F547-L551 HydrophobicContact CD2-CD2 3.66Å; F547-L551 HydrophobicContact CE2-CB 4.41Å; F547-L551 HydrophobicContact CE2-CD2 3.17Å; F547-L551 HydrophobicContact CE2-CG 4.35Å; F547-L551 HydrophobicContact CZ-CD2 3.89Å; F547-L551 WeakPolarHBondContact O-CA 3.27Å; F547-L551 VanDerWaalsContact O-CB 3.25Å; F547-L551 WeakPolarHBondContact O-CB 3.42Å; F547-L551 PolarHBondContact O-N 3.33Å; F547-L552 HydrophobicContact CE1-CB 4.41Å; F547-L552 HydrophobicContact CE1-CD1 4.05Å; F547-L552 PolarHBondContact O-N 3.44Å; F547-L568 HydrophobicContact CE1-CD2 4Å; F547-L568 HydrophobicContact CZ-CD2 3.86Å
548	I	76.3	Confident	73.6	Confident	0 Å²	0	47.6 Å²	47.6	0%	0	25%	0.248	C	C	.	.	I	π-helix	trans	-63.4	-50.9	178.5	-67.7	165.4	0	0	0	110.1	F536 L544 N545 L553 Y598 K601 I602 L605	F536-I548 HydrophobicContact CD1-CD1 4.21Å; F536-I548 HydrophobicContact CE1-CD1 3.87Å; F536-I548 HydrophobicContact CE1-CG1 4Å; L544-I548 HydrophobicContact CD1-CD1 4.49Å; L544-I548 HydrophobicContact CG-CD1 4.2Å; L544-I548 VanDerWaalsContact O-CG1 3.29Å; L544-I548 WeakPolarHBondContact O-CG1 3.49Å; L544-I548 PolarHBondContact O-N 3.33Å; N545-I548 PolarHBondContact O-N 2.96Å; I548-L553 WeakPolarHBondContact O-CG 3.28Å; I548-L553 PolarHBondContact O-N 3.29Å; I548-Y598 HydrophobicContact CD1-CD1 3.34Å; I548-Y598 HydrophobicContact CD1-CE1 3.97Å; I548-Y598 HydrophobicContact CD1-CG 4.15Å; I548-K601 HydrophobicContact CG2-CD 4.28Å; I548-I602 HydrophobicContact CD1-CD1 4.36Å; I548-I602 HydrophobicContact CD1-CG1 4.4Å; I548-I602 HydrophobicContact CG2-CG1 4.43Å; I548-L605 HydrophobicContact CG2-CD1 3.91Å
549	D	75.6	Confident	74.5	Confident	58 Å²	58	49.9 Å²	49.9	31%	0.31	26%	0.259	S	S	.	.	I	π-helix	trans	-72.1	-40.1	-172.3	-68.1	-24.5	0	0	0	112.7	N545 K601	N545-D549 WeakPolarHBondContact O-CB 3.34Å; N545-D549 VanDerWaalsContact O-CG 3.29Å; N545-D549 PolarHBondContact O-N 3.47Å; D549-K601 WeakPolarHBondContact OD1-CE 3.34Å; D549-K601 IonicContact OD1-NZ 2.78Å; D549-K601 PolarHBondContact OD1-NZ 2.94Å; D549-K601 IonicContact OD2-NZ 2.74Å; D549-K601 PolarHBondContact OD2-NZ 3.02Å
550	F	73.5	Confident	75.6	Confident	97 Å²	97	46.1 Å²	46.1	43%	0.425	24%	0.244	S	C	.	.	I	π-helix	trans	-102	-29.2	-172.1	-63.2	-65.9	0	0	0	114.3	Y507 D546 K554	Y507-F550 HydrophobicContact CE1-CB 3.74Å; Y507-F550 VanDerWaalsContact CZ-O 3.25Å; Y507-F550 WeakPolarHBondContact OH-CB 3.38Å; Y507-F550 PolarHBondContact OH-O 2.99Å; D546-F550 HydrophobicContact CB-CD2 3.88Å; D546-F550 HydrophobicContact CB-CE2 4.32Å; D546-F550 WeakPolarHBondContact O-CA 3.46Å; D546-F550 WeakPolarHBondContact O-CB 3.42Å; D546-F550 WeakPolarHBondContact O-CD2 3.09Å; D546-F550 PolarHBondContact O-N 3.48Å; D546-F550 WeakPolarHBondContact OD1-CE2 3.38Å; F550-K554 VanDerWaalsContact O-CB 3.26Å; F550-K554 WeakPolarHBondContact O-CB 3.07Å; F550-K554 VanDerWaalsContact O-CD 3.32Å; F550-K554 WeakPolarHBondContact O-CD 3.47Å
551	L	78.7	Confident	77	Confident	4 Å²	4	41 Å²	41	2%	0.021	21%	0.208	C	C	.	.	I	π-helix	trans	-101.1	-57.2	-179.4	-167.2	81	0	0	0	111.6	I503 Y507 L520 F547 K554 L555	I503-L551 HydrophobicContact CG2-CD2 4.08Å; Y507-L551 HydrophobicContact CD2-CD1 3.36Å; Y507-L551 HydrophobicContact CE2-CD1 3.79Å; Y507-L551 HydrophobicContact CG-CD1 4.2Å; L520-L551 HydrophobicContact CD1-CD1 4.32Å; F547-L551 HydrophobicContact CD2-CB 4.21Å; F547-L551 HydrophobicContact CD2-CD2 3.66Å; F547-L551 HydrophobicContact CE2-CB 4.41Å; F547-L551 HydrophobicContact CE2-CD2 3.17Å; F547-L551 HydrophobicContact CE2-CG 4.35Å; F547-L551 HydrophobicContact CZ-CD2 3.89Å; F547-L551 WeakPolarHBondContact O-CA 3.27Å; F547-L551 VanDerWaalsContact O-CB 3.25Å; F547-L551 WeakPolarHBondContact O-CB 3.42Å; F547-L551 PolarHBondContact O-N 3.33Å; L551-K554 WeakPolarHBondContact O-CB 3.26Å; L551-K554 PolarHBondContact O-N 3.37Å; L551-L555 HydrophobicContact CD1-CD1 4.16Å; L551-L555 HydrophobicContact CD2-CD1 4.06Å; L551-L555 HydrophobicContact CG-CD1 3.69Å; L551-L555 HydrophobicContact CG-CG 4.45Å; L551-L555 WeakPolarHBondContact O-CB 3.49Å; L551-L555 WeakPolarHBondContact O-CG 3.49Å; L551-L555 PolarHBondContact O-N 2.9Å
552	L	80.9	Confident	77.8	Confident	11 Å²	11	39.4 Å²	39.4	6%	0.058	20%	0.2	C	C	.	.	I	π-helix	trans	-65.3	-50.8	-169.2	-167	148.1	0	0	0	112.2	F536 F547 K554 L555 F556 V565 L568 L569	F536-L552 HydrophobicContact CZ-CD1 4.44Å; F547-L552 HydrophobicContact CE1-CB 4.41Å; F547-L552 HydrophobicContact CE1-CD1 4.05Å; F547-L552 PolarHBondContact O-N 3.44Å; L552-K554 PolarHBondContact O-N 3.38Å; L552-L555 PolarHBondContact O-N 3.49Å; L552-F556 WeakPolarHBondContact O-CB 3.5Å; L552-F556 PolarHBondContact O-N 3.17Å; L552-V565 HydrophobicContact CD1-CG1 4.29Å; L552-V565 HydrophobicContact CD2-CG1 3.6Å; L552-V565 HydrophobicContact CG-CG1 3.7Å; L552-V565 HydrophobicContact CG-CG2 4.27Å; L552-L568 HydrophobicContact CD1-CD2 4.25Å; L552-L569 HydrophobicContact CD1-CD2 4.14Å
553	L	75.2	Confident	78.4	Confident	34 Å²	34	36 Å²	36	18%	0.178	18%	0.183	C	C	.	.	H	α-helix	trans	-54.3	-44.8	176.5	-78	-174.2	0	0	0	113.1	I548 F556 L605 H609	I548-L553 WeakPolarHBondContact O-CG 3.28Å; I548-L553 PolarHBondContact O-N 3.29Å; L553-F556 PolarHBondContact O-N 3.23Å; L553-L605 HydrophobicContact CD1-CD1 3.97Å; L553-L605 HydrophobicContact CD1-CD2 4.03Å; L553-L605 HydrophobicContact CD2-CB 3.63Å; L553-L605 HydrophobicContact CD2-CD1 3.62Å; L553-L605 HydrophobicContact CD2-CD2 3.87Å; L553-L605 HydrophobicContact CD2-CG 3.85Å; L553-L605 HydrophobicContact CG-CD1 3.94Å; L553-H609 WeakPolarHBondContact CD2-NE2 3.26Å
554	K	78.5	Confident	79.1	Confident	94 Å²	94	36.2 Å²	36.2	41%	0.409	18%	0.183	S	C	.	.	H	α-helix	trans	-65.8	-53.1	-176.2	-111.5	-158.9	-147.4	172.1	0	108.3	Y507 W513 F550 L551 L552 F556 S557	Y507-K554 WeakPolarHBondContact OH-CD 3.46Å; Y507-K554 WeakPolarHBondContact OH-CE 3.42Å; Y507-K554 PolarHBondContact OH-NZ 3.45Å; W513-K554 HydrophobicContact CH2-CB 4.4Å; W513-K554 WeakPolarHBondContact CH2-O 3.44Å; W513-K554 HydrophobicContact CZ2-CB 3.22Å; W513-K554 HydrophobicContact CZ2-CD 3.82Å; W513-K554 HydrophobicContact CZ2-CG 3.52Å; W513-K554 WeakPolarHBondContact CZ2-O 3.46Å; W513-K554 VanDerWaalsContact NE1-CD 3.35Å; F550-K554 VanDerWaalsContact O-CB 3.26Å; F550-K554 WeakPolarHBondContact O-CB 3.07Å; F550-K554 VanDerWaalsContact O-CD 3.32Å; F550-K554 WeakPolarHBondContact O-CD 3.47Å; L551-K554 WeakPolarHBondContact O-CB 3.26Å; L551-K554 PolarHBondContact O-N 3.37Å; L552-K554 PolarHBondContact O-N 3.38Å; K554-F556 VanDerWaalsContact C-N 3.26Å; K554-F556 PolarHBondContact O-N 3.07Å; K554-S557 WeakPolarHBondContact O-CB 3.43Å; K554-S557 PolarHBondContact O-N 3.04Å; K554-S557 VanDerWaalsContact O-N 3.16Å; K554-S557 PolarHBondContact O-OG 3.38Å
555	L	81.9	Confident	79.8	Confident	1 Å²	1	36.2 Å²	36.2	1%	0.005	18%	0.183	C	C	.	.	H	α-helix	trans	-59.4	-37.4	178.6	-81	168.6	0	0	0	113.6	G517 I518 C521 L551 L552 S557 L558 G561 V565	G517-L555 VanDerWaalsContact O-CD1 3.24Å; G517-L555 WeakPolarHBondContact O-CD1 3.04Å; I518-L555 HydrophobicContact CG1-CD2 4.07Å; I518-L555 VanDerWaalsContact N-CD2 3.34Å; C521-L555 HydrophobicContact CB-CD1 3.85Å; L551-L555 HydrophobicContact CD1-CD1 4.16Å; L551-L555 HydrophobicContact CD2-CD1 4.06Å; L551-L555 HydrophobicContact CG-CD1 3.69Å; L551-L555 HydrophobicContact CG-CG 4.45Å; L551-L555 WeakPolarHBondContact O-CB 3.49Å; L551-L555 WeakPolarHBondContact O-CG 3.49Å; L551-L555 PolarHBondContact O-N 2.9Å; L552-L555 PolarHBondContact O-N 3.49Å; L555-S557 PolarHBondContact O-N 3.25Å; L555-S557 VanDerWaalsContact O-N 3.14Å; L555-L558 HydrophobicContact CD2-CD1 4.07Å; L555-L558 WeakPolarHBondContact O-CB 3.16Å; L555-L558 PolarHBondContact O-N 3.14Å; L555-G561 CarbonylContact O-C 3.58Å; L555-G561 VanDerWaalsContact O-CA 3.3Å; L555-G561 WeakPolarHBondContact O-CA 3.35Å; L555-V565 HydrophobicContact CB-CG2 3.66Å
556	F	81.7	Confident	80.4	Confident	5 Å²	5	33.7 Å²	33.7	2%	0.022	17%	0.17	C	C	.	.	H	α-helix	trans	-59.2	-28.5	-179.4	-167.1	-101	0	0	0	112.4	L552 L553 K554 L558 A562 V565 M566 L606 H609 L610 Q613	L552-F556 WeakPolarHBondContact O-CB 3.5Å; L552-F556 PolarHBondContact O-N 3.17Å; L553-F556 PolarHBondContact O-N 3.23Å; K554-F556 VanDerWaalsContact C-N 3.26Å; K554-F556 PolarHBondContact O-N 3.07Å; F556-L558 PolarHBondContact O-N 2.81Å; F556-A562 HydrophobicContact CD2-CB 4.19Å; F556-A562 HydrophobicContact CE2-CB 4.23Å; F556-A562 WeakPolarHBondContact O-CB 3.34Å; F556-V565 HydrophobicContact CB-CG1 4.45Å; F556-V565 HydrophobicContact CB-CG2 4.5Å; F556-V565 HydrophobicContact CD2-CB 4.06Å; F556-V565 HydrophobicContact CD2-CG1 3.79Å; F556-M566 HydrophobicContact CE2-CG 3.94Å; F556-M566 HydrophobicContact CE2-SD 3.8Å; F556-L606 HydrophobicContact CD2-CD1 4.34Å; F556-L606 HydrophobicContact CE1-CD1 4.09Å; F556-L606 HydrophobicContact CE2-CD1 3.57Å; F556-L606 HydrophobicContact CZ-CD1 3.42Å; F556-L606 VanDerWaalsContact CZ-CD1 3.42Å; F556-H609 HydrophobicContact CD1-CB 3.61Å; F556-H609 HydrophobicContact CE1-CB 3.74Å; F556-L610 HydrophobicContact CE1-CD2 4.29Å; F556-L610 HydrophobicContact CE1-CG 4.33Å; F556-L610 HydrophobicContact CZ-CD2 3.78Å; F556-L610 HydrophobicContact CZ-CG 4.08Å; F556-Q613 VanDerWaalsContact CZ-OE1 3.31Å; F556-Q613 PolarHBondContact O-NE2 2.9Å
557	S	78.9	Confident	81	Confident	73 Å²	73	33.9 Å²	33.9	51%	0.51	17%	0.169	S	C	.	.	T	Hydrogen-bonded Turn	trans	-72.6	-9.2	176.7	72	0	0	0	0	115.2	K554 L555	K554-S557 WeakPolarHBondContact O-CB 3.43Å; K554-S557 PolarHBondContact O-N 3.04Å; K554-S557 VanDerWaalsContact O-N 3.16Å; K554-S557 PolarHBondContact O-OG 3.38Å; L555-S557 PolarHBondContact O-N 3.25Å; L555-S557 VanDerWaalsContact O-N 3.14Å
558	L	79.2	Confident	81.5	Confident	37 Å²	37	33.5 Å²	33.5	19%	0.194	17%	0.167	C	C	.	.	S	Bend	trans	-94.8	146.9	177.3	-66	169.2	0	0	0	111.6	W513 S514 L555 F556 L560 G561 A562	W513-L558 HydrophobicContact CD2-CD1 4.48Å; W513-L558 HydrophobicContact CE3-CD1 3.85Å; W513-L558 HydrophobicContact CE3-CD2 4.35Å; W513-L558 HydrophobicContact CE3-CG 4.36Å; W513-L558 HydrophobicContact CH2-CD1 3.76Å; W513-L558 HydrophobicContact CH2-CD2 4.07Å; W513-L558 HydrophobicContact CH2-CG 3.65Å; W513-L558 HydrophobicContact CZ2-CD1 4.4Å; W513-L558 HydrophobicContact CZ3-CD1 3.46Å; W513-L558 VanDerWaalsContact CZ3-CD1 3.46Å; W513-L558 HydrophobicContact CZ3-CD2 3.48Å; W513-L558 VanDerWaalsContact CZ3-CD2 3.48Å; W513-L558 HydrophobicContact CZ3-CG 3.49Å; W513-L558 VanDerWaalsContact CZ3-CG 3.49Å; S514-L558 VanDerWaalsContact CA-CD1 3.49Å; L555-L558 HydrophobicContact CD2-CD1 4.07Å; L555-L558 WeakPolarHBondContact O-CB 3.16Å; L555-L558 PolarHBondContact O-N 3.14Å; F556-L558 PolarHBondContact O-N 2.81Å; L558-L560 PolarHBondContact O-N 3.03Å; L558-G561 PolarHBondContact O-N 3.18Å; L558-G561 VanDerWaalsContact O-N 3.11Å; L558-A562 PolarHBondContact O-N 3.42Å
559	E	76.7	Confident	82.2	Confident	89 Å²	89	33.5 Å²	33.5	42%	0.416	17%	0.168	S	C	.	.	H	α-helix	trans	-53.4	-54.7	179.8	177.5	166	-148.8	0	0	114.2	P625 C627 Y628	E559-P625 WeakPolarHBondContact OE1-CB 3.25Å; E559-P625 WeakPolarHBondContact OE1-CG 3.29Å; E559-C627 WeakPolarHBondContact CG-SG 3.1Å; E559-Y628 HydrophobicContact CB-CE1 4.15Å; E559-Y628 WeakPolarHBondContact CB-OH 3.39Å; E559-Y628 HydrophobicContact CG-CE1 3.88Å; E559-Y628 HydrophobicContact CG-CE2 4.14Å; E559-Y628 WeakPolarHBondContact CG-OH 3.46Å
560	L	78.2	Confident	82.8	Confident	96 Å²	96	32.6 Å²	32.6	50%	0.503	16%	0.16	S	C	.	.	H	α-helix	trans	-80.6	-21.5	175.7	-72.3	172.7	0	0	0	112.7	I518 L558 E564 C627	I518-L560 HydrophobicContact CD1-CB 3.59Å; I518-L560 HydrophobicContact CG1-CB 4.5Å; L558-L560 PolarHBondContact O-N 3.03Å; L560-E564 PolarHBondContact O-N 3.02Å; L560-C627 HydrophobicContact CD2-CB 3.93Å
561	G	83	Confident	83.4	Confident	0 Å²	0	28.2 Å²	28.2	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-74.4	-34.9	-178.3	0	0	0	0	0	113	L555 L558 K563 E564 V565	L555-G561 CarbonylContact O-C 3.58Å; L555-G561 VanDerWaalsContact O-CA 3.3Å; L555-G561 WeakPolarHBondContact O-CA 3.35Å; L558-G561 PolarHBondContact O-N 3.18Å; L558-G561 VanDerWaalsContact O-N 3.11Å; G561-K563 VanDerWaalsContact C-N 3.3Å; G561-K563 PolarHBondContact O-N 3.23Å; G561-E564 PolarHBondContact O-N 3.4Å; G561-V565 WeakPolarHBondContact O-CB 3.29Å; G561-V565 VanDerWaalsContact O-CG2 3.32Å; G561-V565 WeakPolarHBondContact O-CG2 3.33Å; G561-V565 PolarHBondContact O-N 3.04Å
562	A	84.2	Confident	83.8	Confident	0 Å²	0	28 Å²	28	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-56.8	-44.3	174.8	0	0	0	0	0	111.8	F556 L558 V565 M566 T631	F556-A562 HydrophobicContact CD2-CB 4.19Å; F556-A562 HydrophobicContact CE2-CB 4.23Å; F556-A562 WeakPolarHBondContact O-CB 3.34Å; L558-A562 PolarHBondContact O-N 3.42Å; A562-V565 PolarHBondContact O-N 2.97Å; A562-M566 WeakPolarHBondContact O-CB 3.49Å; A562-M566 WeakPolarHBondContact O-CG 3.13Å; A562-M566 PolarHBondContact O-N 2.76Å; A562-T631 HydrophobicContact CB-CG2 3.92Å
563	K	85.3	Confident	83.9	Confident	35 Å²	35	27.5 Å²	27.5	15%	0.152	14%	0.138	C	C	.	.	H	α-helix	trans	-57.4	-54	175.5	177.4	-167.4	171.6	167.9	0	111.9	G561 V565 M566 F567 E630 T631 L634	G561-K563 VanDerWaalsContact C-N 3.3Å; G561-K563 PolarHBondContact O-N 3.23Å; K563-V565 VanDerWaalsContact C-N 3.32Å; K563-V565 PolarHBondContact O-N 3.22Å; K563-M566 PolarHBondContact O-N 3.38Å; K563-F567 WeakPolarHBondContact O-CB 3.27Å; K563-F567 PolarHBondContact O-N 3.41Å; K563-E630 HydrophobicContact CD-CB 4.33Å; K563-E630 VanDerWaalsContact CD-OE2 3.26Å; K563-E630 WeakPolarHBondContact CD-OE2 3.37Å; K563-E630 WeakPolarHBondContact CE-OE2 3.25Å; K563-E630 HydrophobicContact CG-CB 4.35Å; K563-E630 IonicContact NZ-OE1 3.01Å; K563-E630 PolarHBondContact NZ-OE1 2.99Å; K563-E630 IonicContact NZ-OE2 2.72Å; K563-E630 PolarHBondContact NZ-OE2 3.39Å; K563-T631 WeakPolarHBondContact CA-OG1 3.45Å; K563-T631 PolarHBondContact N-OG1 3.41Å; K563-L634 HydrophobicContact CG-CD1 4.12Å
564	E	87	Confident	84.3	Confident	25 Å²	25	29.1 Å²	29.1	12%	0.117	14%	0.144	C	C	.	.	H	α-helix	trans	-65.6	-36.4	-176.7	-64.7	-53.3	139.2	0	0	112.1	I518 C521 L560 G561 F567 L568	I518-E564 HydrophobicContact CG2-CG 3.71Å; C521-E564 HydrophobicContact CB-CB 4.18Å; C521-E564 PolarHBondContact SG-O 3.05Å; L560-E564 PolarHBondContact O-N 3.02Å; G561-E564 PolarHBondContact O-N 3.4Å; E564-F567 PolarHBondContact O-N 3.27Å; E564-L568 WeakPolarHBondContact O-CB 3.27Å; E564-L568 PolarHBondContact O-N 3.5Å
565	V	88.7	Confident	84.4	Confident	1 Å²	1	24.9 Å²	24.9	1%	0.006	13%	0.126	C	C	.	.	H	α-helix	trans	-64.1	-47	173.5	168.8	0	0	0	0	110.6	L552 L555 F556 G561 A562 K563 F567 L568 L569	L552-V565 HydrophobicContact CD1-CG1 4.29Å; L552-V565 HydrophobicContact CD2-CG1 3.6Å; L552-V565 HydrophobicContact CG-CG1 3.7Å; L552-V565 HydrophobicContact CG-CG2 4.27Å; L555-V565 HydrophobicContact CB-CG2 3.66Å; F556-V565 HydrophobicContact CB-CG1 4.45Å; F556-V565 HydrophobicContact CB-CG2 4.5Å; F556-V565 HydrophobicContact CD2-CB 4.06Å; F556-V565 HydrophobicContact CD2-CG1 3.79Å; G561-V565 WeakPolarHBondContact O-CB 3.29Å; G561-V565 VanDerWaalsContact O-CG2 3.32Å; G561-V565 WeakPolarHBondContact O-CG2 3.33Å; G561-V565 PolarHBondContact O-N 3.04Å; A562-V565 PolarHBondContact O-N 2.97Å; K563-V565 VanDerWaalsContact C-N 3.32Å; K563-V565 PolarHBondContact O-N 3.22Å; V565-F567 VanDerWaalsContact C-N 3.26Å; V565-F567 PolarHBondContact O-N 3.08Å; V565-L568 WeakPolarHBondContact O-CB 3.35Å; V565-L568 PolarHBondContact O-N 2.95Å; V565-L569 HydrophobicContact CG1-CD1 4.22Å; V565-L569 HydrophobicContact CG1-CG 4.4Å; V565-L569 WeakPolarHBondContact O-CG 3.36Å; V565-L569 PolarHBondContact O-N 2.9Å
566	M	89.2	Confident	84.3	Confident	0 Å²	0	25 Å²	25	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-63.1	-35.2	177.3	-72.3	-49.3	-49.8	0	0	112.2	F556 A562 K563 L569 Y570 L606 T631 L634 L635 F638	F556-M566 HydrophobicContact CE2-CG 3.94Å; F556-M566 HydrophobicContact CE2-SD 3.8Å; A562-M566 WeakPolarHBondContact O-CB 3.49Å; A562-M566 WeakPolarHBondContact O-CG 3.13Å; A562-M566 PolarHBondContact O-N 2.76Å; K563-M566 PolarHBondContact O-N 3.38Å; M566-L569 PolarHBondContact O-N 3.44Å; M566-L569 HydrophobicContact SD-CD1 4.21Å; M566-Y570 VanDerWaalsContact O-CB 3.26Å; M566-Y570 WeakPolarHBondContact O-CB 3.37Å; M566-Y570 PolarHBondContact O-N 2.93Å; M566-L606 HydrophobicContact CE-CD2 4.46Å; M566-L606 HydrophobicContact SD-CD1 3.67Å; M566-L606 HydrophobicContact SD-CD2 4.3Å; M566-T631 HydrophobicContact CB-CG2 4.44Å; M566-T631 HydrophobicContact CG-CG2 3.72Å; M566-L634 HydrophobicContact CB-CB 3.8Å; M566-L634 HydrophobicContact CB-CD1 4.28Å; M566-L635 HydrophobicContact CE-CB 3.91Å; M566-L635 HydrophobicContact CE-CD1 3.54Å; M566-L635 HydrophobicContact CE-CG 4.35Å; M566-L635 HydrophobicContact SD-CD1 4.21Å; M566-F638 HydrophobicContact CE-CB 4.13Å; M566-F638 HydrophobicContact CE-CD1 4.27Å; M566-F638 HydrophobicContact CE-CG 4.23Å
567	F	89.1	Confident	84	Confident	43 Å²	43	27 Å²	27	19%	0.189	13%	0.134	C	C	.	.	H	α-helix	trans	-66.8	-41.7	175.4	-172.5	-135.5	0	0	0	112	T525 K563 E564 V565 Y570 T571 L634	T525-F567 HydrophobicContact CG2-CD1 3.51Å; T525-F567 HydrophobicContact CG2-CE1 3.59Å; T525-F567 HydrophobicContact CG2-CG 4.08Å; T525-F567 HydrophobicContact CG2-CZ 4.22Å; K563-F567 WeakPolarHBondContact O-CB 3.27Å; K563-F567 PolarHBondContact O-N 3.41Å; E564-F567 PolarHBondContact O-N 3.27Å; V565-F567 VanDerWaalsContact C-N 3.26Å; V565-F567 PolarHBondContact O-N 3.08Å; F567-Y570 HydrophobicContact CD2-CD1 4.35Å; F567-T571 VanDerWaalsContact O-CB 3.28Å; F567-T571 WeakPolarHBondContact O-CB 3.35Å; F567-T571 PolarHBondContact O-N 2.76Å; F567-T571 PolarHBondContact O-OG1 3.47Å; F567-L634 HydrophobicContact CB-CD1 3.88Å; F567-L634 HydrophobicContact CB-CD2 4.4Å; F567-L634 HydrophobicContact CD2-CD2 3.87Å
568	L	90.2	Very high	83.8	Confident	0 Å²	0	26.1 Å²	26.1	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-58.4	-49.2	172.7	-179.7	68.6	0	0	0	111.6	L524 T525 I528 I535 F547 L552 E564 V565 T571 N572	L524-L568 HydrophobicContact CD2-CD1 4.21Å; L524-L568 HydrophobicContact CD2-CD2 4.29Å; L524-L568 HydrophobicContact CG-CD1 4.12Å; T525-L568 WeakPolarHBondContact OG1-CA 3.5Å; T525-L568 WeakPolarHBondContact OG1-CB 3.13Å; T525-L568 WeakPolarHBondContact OG1-CD1 3.3Å; I528-L568 HydrophobicContact CD1-CD1 3.66Å; I535-L568 HydrophobicContact CD1-CD1 4.48Å; F547-L568 HydrophobicContact CE1-CD2 4Å; F547-L568 HydrophobicContact CZ-CD2 3.86Å; L552-L568 HydrophobicContact CD1-CD2 4.25Å; E564-L568 WeakPolarHBondContact O-CB 3.27Å; E564-L568 PolarHBondContact O-N 3.5Å; V565-L568 WeakPolarHBondContact O-CB 3.35Å; V565-L568 PolarHBondContact O-N 2.95Å; L568-T571 PolarHBondContact O-N 3.21Å; L568-N572 PolarHBondContact O-N 3.05Å; L568-N572 PolarHBondContact O-ND2 3.45Å
569	L	90.3	Very high	83.6	Confident	1 Å²	1	26.1 Å²	26.1	1%	0.005	12%	0.124	C	C	.	.	H	α-helix	trans	-64.3	-46	-178.9	-66.7	-177.7	0	0	0	111.7	F536 L552 V565 M566 T571 N572 M573 W599 I602 F638	F536-L569 HydrophobicContact CE2-CD2 3.89Å; F536-L569 HydrophobicContact CZ-CD2 4.15Å; L552-L569 HydrophobicContact CD1-CD2 4.14Å; V565-L569 HydrophobicContact CG1-CD1 4.22Å; V565-L569 HydrophobicContact CG1-CG 4.4Å; V565-L569 WeakPolarHBondContact O-CG 3.36Å; V565-L569 PolarHBondContact O-N 2.9Å; M566-L569 PolarHBondContact O-N 3.44Å; M566-L569 HydrophobicContact SD-CD1 4.21Å; L569-T571 PolarHBondContact O-N 2.86Å; L569-N572 PolarHBondContact O-N 3.43Å; L569-M573 PolarHBondContact O-N 2.91Å; L569-W599 HydrophobicContact CD2-CZ3 4.12Å; L569-I602 HydrophobicContact CD1-CG2 3.73Å; L569-I602 HydrophobicContact CD2-CD1 4.02Å; L569-I602 HydrophobicContact CD2-CG2 3.72Å; L569-I602 HydrophobicContact CG-CG2 4.38Å; L569-F638 HydrophobicContact CB-CD2 4.08Å; L569-F638 HydrophobicContact CB-CE2 3.95Å
570	Y	88.3	Confident	83.2	Confident	39 Å²	39	23.8 Å²	23.8	15%	0.153	11%	0.114	C	C	.	.	H	α-helix	trans	-58	-47.7	174.7	168.3	-104.9	0	0	0	111.6	M566 F567 N572 M573 H574 L634 K637 M641	M566-Y570 VanDerWaalsContact O-CB 3.26Å; M566-Y570 WeakPolarHBondContact O-CB 3.37Å; M566-Y570 PolarHBondContact O-N 2.93Å; F567-Y570 HydrophobicContact CD2-CD1 4.35Å; Y570-N572 PolarHBondContact O-N 3.46Å; Y570-M573 PolarHBondContact O-N 3.26Å; Y570-H574 VanDerWaalsContact O-CB 3.31Å; Y570-H574 WeakPolarHBondContact O-CB 3.46Å; Y570-H574 PolarHBondContact O-N 3.45Å; Y570-L634 HydrophobicContact CD1-CD2 4.28Å; Y570-L634 HydrophobicContact CG-CD2 4.47Å; Y570-K637 HydrophobicContact CD2-CB 3.72Å; Y570-K637 HydrophobicContact CE2-CB 3.62Å; Y570-K637 HydrophobicContact CE2-CD 4.28Å; Y570-K637 HydrophobicContact CE2-CG 4.49Å; Y570-M641 HydrophobicContact CD2-CG 4.36Å; Y570-M641 HydrophobicContact CE2-CG 3.94Å
571	T	85.9	Confident	82.5	Confident	5 Å²	5	22.2 Å²	22.2	3%	0.031	11%	0.106	C	C	.	.	H	α-helix	trans	-62	-45.4	-178.7	-59.1	0	0	0	0	111.4	T525 I528 Q529 F567 L568 L569 H574 I575	T525-T571 HydrophobicContact CG2-CG2 4.24Å; I528-T571 HydrophobicContact CD1-CG2 4.02Å; I528-T571 HydrophobicContact CG1-CG2 4.16Å; Q529-T571 HydrophobicContact CB-CG2 4Å; Q529-T571 HydrophobicContact CG-CG2 4.35Å; F567-T571 VanDerWaalsContact O-CB 3.28Å; F567-T571 WeakPolarHBondContact O-CB 3.35Å; F567-T571 PolarHBondContact O-N 2.76Å; F567-T571 PolarHBondContact O-OG1 3.47Å; L568-T571 PolarHBondContact O-N 3.21Å; L569-T571 PolarHBondContact O-N 2.86Å; T571-H574 PolarHBondContact O-N 3.01Å; T571-I575 HydrophobicContact CG2-CD1 4Å; T571-I575 VanDerWaalsContact O-CG1 3.29Å; T571-I575 WeakPolarHBondContact O-CG1 3.4Å; T571-I575 PolarHBondContact O-N 3.17Å
572	N	87.1	Confident	81.4	Confident	0 Å²	0	27.8 Å²	27.8	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-59.6	-47.1	175.1	-84.7	-85.1	0	0	0	112.1	I528 I535 F536 L568 L569 Y570 H574 I575 M576 W599	I528-N572 WeakPolarHBondContact CD1-ND2 3.37Å; I535-N572 PolarHBondContact N-OD1 3.29Å; F536-N572 HydrophobicContact CD2-CB 3.9Å; F536-N572 HydrophobicContact CE2-CB 4.09Å; L568-N572 PolarHBondContact O-N 3.05Å; L568-N572 PolarHBondContact O-ND2 3.45Å; L569-N572 PolarHBondContact O-N 3.43Å; Y570-N572 PolarHBondContact O-N 3.46Å; N572-H574 VanDerWaalsContact C-N 3.3Å; N572-H574 PolarHBondContact O-N 2.94Å; N572-I575 PolarHBondContact O-N 2.85Å; N572-M576 WeakPolarHBondContact O-CB 3.38Å; N572-M576 PolarHBondContact O-N 2.81Å; N572-W599 HydrophobicContact CB-CH2 3.78Å; N572-W599 HydrophobicContact CB-CZ2 3.9Å
573	M	84.2	Confident	79.9	Confident	0 Å²	0	31.7 Å²	31.7	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-62.6	-38.3	177.3	-78.2	-59.1	-59.1	0	0	112.5	L569 Y570 M576 Y577 W599 F638 I642 I648	L569-M573 PolarHBondContact O-N 2.91Å; Y570-M573 PolarHBondContact O-N 3.26Å; M573-M576 HydrophobicContact CE-CE 3.79Å; M573-M576 PolarHBondContact O-N 3.23Å; M573-M576 HydrophobicContact SD-CE 3.6Å; M573-M576 VanDerWaalsContact SD-CE 3.6Å; M573-Y577 VanDerWaalsContact O-CB 3.31Å; M573-Y577 WeakPolarHBondContact O-CB 3.31Å; M573-Y577 PolarHBondContact O-N 2.82Å; M573-W599 HydrophobicContact CB-CH2 4.43Å; M573-W599 HydrophobicContact CG-CE3 4.5Å; M573-W599 HydrophobicContact CG-CH2 3.41Å; M573-W599 VanDerWaalsContact CG-CH2 3.41Å; M573-W599 HydrophobicContact CG-CZ2 3.84Å; M573-W599 HydrophobicContact CG-CZ3 3.79Å; M573-W599 HydrophobicContact SD-CD2 3.89Å; M573-W599 VanDerWaalsContact SD-CE2 3.59Å; M573-W599 HydrophobicContact SD-CE3 3.98Å; M573-W599 HydrophobicContact SD-CH2 3.53Å; M573-W599 VanDerWaalsContact SD-CH2 3.53Å; M573-W599 HydrophobicContact SD-CZ2 3.39Å; M573-W599 WeakPolarHBondContact SD-CZ2 3.45Å; M573-W599 HydrophobicContact SD-CZ3 3.82Å; M573-F638 HydrophobicContact CB-CD2 4.24Å; M573-F638 HydrophobicContact CB-CE2 4.37Å; M573-F638 HydrophobicContact CG-CD2 3.58Å; M573-F638 HydrophobicContact CG-CE2 3.28Å; M573-F638 HydrophobicContact CG-CZ 4.34Å; M573-F638 HydrophobicContact SD-CE2 4.34Å; M573-I642 HydrophobicContact CE-CB 4.46Å; M573-I642 HydrophobicContact CE-CG1 3.51Å; M573-I642 HydrophobicContact SD-CG1 4.39Å; M573-I648 HydrophobicContact CE-CD1 3.47Å; M573-I648 VanDerWaalsContact CE-CD1 3.47Å
574	H	82.2	Confident	78	Confident	68 Å²	68	35.3 Å²	35.3	32%	0.315	18%	0.178	S	C	.	.	H	α-helix	trans	-67.1	-42.5	179	176.3	-93.1	0	0	0	112.2	Y570 T571 N572 Y577 N578 M641	Y570-H574 VanDerWaalsContact O-CB 3.31Å; Y570-H574 WeakPolarHBondContact O-CB 3.46Å; Y570-H574 PolarHBondContact O-N 3.45Å; T571-H574 PolarHBondContact O-N 3.01Å; N572-H574 VanDerWaalsContact C-N 3.3Å; N572-H574 PolarHBondContact O-N 2.94Å; H574-Y577 PolarHBondContact O-N 2.89Å; H574-N578 PolarHBondContact CE1-ND2 3.24Å; H574-N578 PolarHBondContact ND1-ND2 2.92Å; H574-N578 PolarHBondContact NE2-ND2 3.14Å; H574-N578 PolarHBondContact O-N 2.88Å; H574-N578 PolarHBondContact O-ND2 2.78Å; H574-M641 HydrophobicContact CB-CE 4.33Å
575	I	81.3	Confident	75.8	Confident	4 Å²	4	38.7 Å²	38.7	2%	0.021	20%	0.204	C	C	.	.	H	α-helix	trans	-60.1	-49	173	-67.4	167	0	0	0	110.1	I528 T571 N572 Y577 N578 N579	I528-I575 HydrophobicContact CB-CD1 4.49Å; I528-I575 HydrophobicContact CG1-CD1 4.49Å; T571-I575 HydrophobicContact CG2-CD1 4Å; T571-I575 VanDerWaalsContact O-CG1 3.29Å; T571-I575 WeakPolarHBondContact O-CG1 3.4Å; T571-I575 PolarHBondContact O-N 3.17Å; N572-I575 PolarHBondContact O-N 2.85Å; I575-Y577 VanDerWaalsContact C-N 3.34Å; I575-Y577 PolarHBondContact O-N 3.46Å; I575-N578 PolarHBondContact O-N 3.21Å; I575-N579 WeakPolarHBondContact O-CB 3.49Å; I575-N579 VanDerWaalsContact O-CG 3.25Å; I575-N579 PolarHBondContact O-N 3Å
576	M	78.6	Confident	73.2	Confident	4 Å²	4	45 Å²	45	2%	0.02	24%	0.238	C	C	.	.	H	α-helix	trans	-61	-39.9	178.6	-175.6	167.1	91.7	0	0	112.6	E537 N572 M573 N580 Y596 I648	E537-M576 HydrophobicContact CG-SD 4.24Å; E537-M576 VanDerWaalsContact OE1-CG 3.27Å; E537-M576 WeakPolarHBondContact OE1-CG 3.36Å; N572-M576 WeakPolarHBondContact O-CB 3.38Å; N572-M576 PolarHBondContact O-N 2.81Å; M573-M576 HydrophobicContact CE-CE 3.79Å; M573-M576 PolarHBondContact O-N 3.23Å; M573-M576 HydrophobicContact SD-CE 3.6Å; M573-M576 VanDerWaalsContact SD-CE 3.6Å; M576-N580 WeakPolarHBondContact O-CB 3.49Å; M576-N580 VanDerWaalsContact O-CG 3.28Å; M576-N580 PolarHBondContact O-N 3.37Å; M576-N580 VanDerWaalsContact O-N 3.11Å; M576-N580 PolarHBondContact O-ND2 3.12Å; M576-Y596 HydrophobicContact CE-CE1 4.22Å; M576-I648 HydrophobicContact CE-CD1 3.16Å; M576-I648 HydrophobicContact CE-CG1 4Å
577	Y	75.8	Confident	70.4	Confident	48 Å²	48	51.8 Å²	51.8	19%	0.188	27%	0.274	C	S	.	.	H	α-helix	trans	-62	-48.6	174.1	177.4	-100.5	0	0	0	112.1	M573 H574 I575 N580 N581 M641 M644 N645	M573-Y577 VanDerWaalsContact O-CB 3.31Å; M573-Y577 WeakPolarHBondContact O-CB 3.31Å; M573-Y577 PolarHBondContact O-N 2.82Å; H574-Y577 PolarHBondContact O-N 2.89Å; I575-Y577 VanDerWaalsContact C-N 3.34Å; I575-Y577 PolarHBondContact O-N 3.46Å; Y577-N580 PolarHBondContact O-N 3.35Å; Y577-N581 WeakPolarHBondContact CE1-ND2 3.38Å; Y577-N581 PolarHBondContact O-N 2.81Å; Y577-N581 PolarHBondContact OH-ND2 3.46Å; Y577-M641 VanDerWaalsContact CB-CE 3.47Å; Y577-M641 HydrophobicContact CD1-CE 3.33Å; Y577-M641 HydrophobicContact CD2-CE 4.11Å; Y577-M641 HydrophobicContact CE1-CE 4.03Å; Y577-M641 HydrophobicContact CG-CE 3.36Å; Y577-M644 HydrophobicContact CE2-CB 4.36Å; Y577-N645 HydrophobicContact CD2-CB 3.72Å; Y577-N645 HydrophobicContact CE2-CB 4.14Å
578	N	76.2	Confident	67.6	Low	53 Å²	53	53.4 Å²	53.4	28%	0.283	30%	0.303	S	S	.	.	H	α-helix	trans	-66.6	-40.3	-179.4	-72	-16.8	0	0	0	112.5	H574 I575 N580 N581 N582	H574-N578 PolarHBondContact CE1-ND2 3.24Å; H574-N578 PolarHBondContact ND1-ND2 2.92Å; H574-N578 PolarHBondContact NE2-ND2 3.14Å; H574-N578 PolarHBondContact O-N 2.88Å; H574-N578 PolarHBondContact O-ND2 2.78Å; I575-N578 PolarHBondContact O-N 3.21Å; N578-N580 VanDerWaalsContact C-N 3.33Å; N578-N580 PolarHBondContact O-N 3.37Å; N578-N581 PolarHBondContact O-N 3.29Å; N578-N582 WeakPolarHBondContact O-CB 3.24Å; N578-N582 PolarHBondContact O-N 3.27Å; N578-N582 PolarHBondContact O-ND2 3.49Å
579	N	73.6	Confident	64.9	Low	37 Å²	37	60.1 Å²	60.1	20%	0.198	34%	0.338	C	S	.	.	H	α-helix	trans	-62.1	-41.8	176.8	-72.1	-9.6	0	0	0	111.1	N532 I575 N583	N532-N579 PolarHBondContact ND2-OD1 2.88Å; I575-N579 WeakPolarHBondContact O-CB 3.49Å; I575-N579 VanDerWaalsContact O-CG 3.25Å; I575-N579 PolarHBondContact O-N 3Å; N579-N583 WeakPolarHBondContact O-CB 3.48Å; N579-N583 VanDerWaalsContact O-CG 3.29Å; N579-N583 PolarHBondContact O-N 3.49Å; N579-N583 PolarHBondContact O-ND2 2.91Å
580	N	69.2	Low	62.3	Low	40 Å²	40	68.6 Å²	68.6	21%	0.214	38%	0.377	C	S	.	.	H	α-helix	trans	-66.8	-43.5	176.2	-75	-38.1	0	0	0	112.7	M576 Y577 N578 N582 N583	M576-N580 WeakPolarHBondContact O-CB 3.49Å; M576-N580 VanDerWaalsContact O-CG 3.28Å; M576-N580 PolarHBondContact O-N 3.37Å; M576-N580 VanDerWaalsContact O-N 3.11Å; M576-N580 PolarHBondContact O-ND2 3.12Å; Y577-N580 PolarHBondContact O-N 3.35Å; N578-N580 VanDerWaalsContact C-N 3.33Å; N578-N580 PolarHBondContact O-N 3.37Å; N580-N582 PolarHBondContact O-N 3.06Å; N580-N583 PolarHBondContact O-N 2.87Å
581	N	63.9	Low	60	Low	63 Å²	63	68.9 Å²	68.9	34%	0.337	39%	0.392	S	S	.	.	H	α-helix	trans	-65.3	-38.5	178.5	-81.5	-8.6	0	0	0	113.3	Y577 N578 N584	Y577-N581 WeakPolarHBondContact CE1-ND2 3.38Å; Y577-N581 PolarHBondContact O-N 2.81Å; Y577-N581 PolarHBondContact OH-ND2 3.46Å; N578-N581 PolarHBondContact O-N 3.29Å; N581-N584 PolarHBondContact O-N 3.49Å
582	N	59	Low	58.1	Low	117 Å²	117	73.9 Å²	73.9	63%	0.626	42%	0.419	S	S	*	.	H	α-helix	trans	-70.8	-33.6	178.9	-74.2	-17	0	0	0	112.4	N578 N580 N584 S585	N578-N582 WeakPolarHBondContact O-CB 3.24Å; N578-N582 PolarHBondContact O-N 3.27Å; N578-N582 PolarHBondContact O-ND2 3.49Å; N580-N582 PolarHBondContact O-N 3.06Å; N582-N584 PolarHBondContact O-N 3.03Å; N582-S585 PolarHBondContact O-OG 3.42Å
583	N	53.7	Low	56	Low	83 Å²	83	81.1 Å²	81.1	44%	0.444	45%	0.452	S	S	.	.	G	3₁₀ helix	trans	-74.3	-4.7	179.5	-75.5	-13.6	0	0	0	114.2	N579 N580 S585 N586	N579-N583 WeakPolarHBondContact O-CB 3.48Å; N579-N583 VanDerWaalsContact O-CG 3.29Å; N579-N583 PolarHBondContact O-N 3.49Å; N579-N583 PolarHBondContact O-ND2 2.91Å; N580-N583 PolarHBondContact O-N 2.87Å; N583-S585 PolarHBondContact O-N 3.17Å; N583-N586 PolarHBondContact O-N 3.42Å
584	N	43.8	Very low	54.3	Low	111 Å²	111	90.6 Å²	90.6	59%	0.594	49%	0.488	S	S	*	.	G	3₁₀ helix	trans	-63.1	-5	174.4	-85.6	-26.1	0	0	0	114.6	N581 N582	N581-N584 PolarHBondContact O-N 3.49Å; N582-N584 PolarHBondContact O-N 3.03Å
585	S	41.4	Very low	53.3	Low	95 Å²	95	89.5 Å²	89.5	66%	0.664	49%	0.485	S	S	*	.	G	3₁₀ helix	trans	-100.4	-10.8	179.6	58.7	0	0	0	0	116.3	N582 N583	N582-S585 PolarHBondContact O-OG 3.42Å; N583-S585 PolarHBondContact O-N 3.17Å
586	N	33.1	Very low	53	Low	133 Å²	133	90.4 Å²	90.4	71%	0.711	49%	0.488	S	S	*	.	S	Bend	trans	-162.5	123.9	170.7	-88.6	-40.5	0	0	0	112.2	N583	N583-N586 PolarHBondContact O-N 3.42Å
587	N	32.1	Very low	53	Low	143 Å²	143	95.4 Å²	95.4	77%	0.765	51%	0.514	S	S	*	.			trans	72.7	109.7	170	-63.5	-18.2	0	0	0	117.4	L589	N587-L589 VanDerWaalsContact C-N 3.33Å; N587-L589 PolarHBondContact O-N 3.09Å
588	G	30.5	Very low	53.3	Low	77 Å²	77	93.7 Å²	93.7	79%	0.794	51%	0.507	S	S	*	.			trans	-54.3	85.3	169.1	0	0	0	0	0	114	H590	G588-H590 PolarHBondContact O-N 2.85Å
589	L	33.2	Very low	53.7	Low	142 Å²	142	91.2 Å²	91.2	74%	0.743	49%	0.494	S	S	*	.			trans	-68	86.9	151.2	-84.2	149.3	0	0	0	106.9	N587 G591	N587-L589 VanDerWaalsContact C-N 3.33Å; N587-L589 PolarHBondContact O-N 3.09Å; L589-G591 VanDerWaalsContact C-N 3.25Å; L589-G591 PolarHBondContact O-N 2.99Å
590	H	34.1	Very low	54.2	Low	178 Å²	178	91.6 Å²	91.6	82%	0.824	50%	0.496	S	S	*	.			trans	-54.7	97.6	155.4	-80.1	-73.4	0	0	0	107.1	G588 N592	G588-H590 PolarHBondContact O-N 2.85Å; H590-N592 PolarHBondContact O-N 3.44Å
591	G	41.3	Very low	55	Low	45 Å²	45	92.3 Å²	92.3	46%	0.464	50%	0.497	S	S	.	.			trans	-51.4	123.7	173.3	0	0	0	0	0	108.7	L589 H593	L589-G591 VanDerWaalsContact C-N 3.25Å; L589-G591 PolarHBondContact O-N 2.99Å; G591-H593 PolarHBondContact O-N 2.97Å
592	N	45	Very low	56.1	Low	111 Å²	111	89.4 Å²	89.4	59%	0.594	48%	0.481	S	S	*	.			trans	-65.7	135.3	-179	-90.1	-39.7	0	0	0	107.3	H590 R594 D595	H590-N592 PolarHBondContact O-N 3.44Å; N592-R594 HydrophobicContact CB-CB 4.49Å; N592-R594 PolarHBondContact O-N 2.95Å; N592-D595 PolarHBondContact N-OD2 2.98Å; N592-D595 WeakPolarHBondContact O-CB 3.29Å; N592-D595 PolarHBondContact O-N 3.24Å
593	H	44.2	Very low	57.5	Low	151 Å²	151	83.9 Å²	83.9	70%	0.699	45%	0.452	S	S	*	.	G	3₁₀ helix	trans	-54.7	-16.9	173.9	-70.1	-68.1	0	0	0	113.7	G591 D595	G591-H593 PolarHBondContact O-N 2.97Å; H593-D595 VanDerWaalsContact C-N 3.28Å; H593-D595 PolarHBondContact O-N 3.33Å
594	R	47.5	Very low	59	Low	199 Å²	199	82.2 Å²	82.2	75%	0.751	45%	0.445	S	S	*	.	G	3₁₀ helix	trans	-66.7	-25.9	173.5	-68.8	-172.1	-177.4	-170.5	1.6	113.4	N592 Y596 L597	N592-R594 HydrophobicContact CB-CB 4.49Å; N592-R594 PolarHBondContact O-N 2.95Å; R594-Y596 PolarHBondContact O-N 3Å; R594-L597 PolarHBondContact O-N 3.06Å
595	D	61.2	Low	61	Low	46 Å²	46	78.7 Å²	78.7	25%	0.246	43%	0.426	C	S	.	.	G	3₁₀ helix	trans	-70.9	-13	-174.2	-51.2	-17.4	0	0	0	111.7	N592 H593	N592-D595 PolarHBondContact N-OD2 2.98Å; N592-D595 WeakPolarHBondContact O-CB 3.29Å; N592-D595 PolarHBondContact O-N 3.24Å; H593-D595 VanDerWaalsContact C-N 3.28Å; H593-D595 PolarHBondContact O-N 3.33Å
596	Y	75	Confident	63.2	Low	22 Å²	22	74.6 Å²	74.6	9%	0.086	40%	0.396	C	S	.	.	G	3₁₀ helix	trans	-99.5	-3.8	-179.5	-62.2	-66.9	0	0	0	114.8	M576 R594 Y598 W599 I600 H647 I648 L651	M576-Y596 HydrophobicContact CE-CE1 4.22Å; R594-Y596 PolarHBondContact O-N 3Å; Y596-Y598 VanDerWaalsContact C-N 3.34Å; Y596-Y598 PolarHBondContact O-N 3.36Å; Y596-W599 WeakPolarHBondContact O-CB 3.47Å; Y596-W599 PolarHBondContact O-N 3.41Å; Y596-W599 VanDerWaalsContact O-N 3.15Å; Y596-I600 WeakPolarHBondContact O-CG1 3.41Å; Y596-I600 PolarHBondContact O-N 3.06Å; Y596-H647 PolarHBondContact OH-O 3.49Å; Y596-H647 VanDerWaalsContact OH-O 3.06Å; Y596-I648 HydrophobicContact CD1-CG2 4.29Å; Y596-I648 HydrophobicContact CE1-CB 4.37Å; Y596-I648 HydrophobicContact CE1-CG1 4.1Å; Y596-I648 HydrophobicContact CE1-CG2 3.77Å; Y596-L651 HydrophobicContact CD1-CD1 4.07Å; Y596-L651 HydrophobicContact CD1-CD2 4.27Å; Y596-L651 HydrophobicContact CD1-CG 3.99Å
597	L	79.1	Confident	65.7	Low	109 Å²	109	68.8 Å²	68.8	57%	0.571	37%	0.365	S	S	*	.	H	α-helix	trans	-60.4	-42.6	-175.7	-74	171.6	0	0	0	112.6	R594 I600 K601	R594-L597 PolarHBondContact O-N 3.06Å; L597-I600 PolarHBondContact O-N 2.96Å; L597-K601 PolarHBondContact O-N 2.9Å; L597-K601 VanDerWaalsContact O-N 3.09Å
598	Y	81.7	Confident	68.2	Low	12 Å²	12	66.5 Å²	66.5	5%	0.047	35%	0.353	C	S	.	.	H	α-helix	trans	-65.3	-40.3	175.9	-72.7	-63	0	0	0	112.1	F536 S540 N541 L544 N545 I548 Y596 K601 I602	F536-Y598 HydrophobicContact CD1-CG 4.5Å; S540-Y598 WeakPolarHBondContact CA-OH 3.12Å; N541-Y598 PolarHBondContact N-OH 3.24Å; N541-Y598 PolarHBondContact O-OH 2.82Å; L544-Y598 HydrophobicContact CB-CE1 4.25Å; L544-Y598 HydrophobicContact CD2-CD1 4.22Å; L544-Y598 HydrophobicContact CD2-CD2 3.8Å; L544-Y598 HydrophobicContact CD2-CE1 4.01Å; L544-Y598 HydrophobicContact CD2-CE2 3.61Å; L544-Y598 HydrophobicContact CD2-CG 4.1Å; L544-Y598 HydrophobicContact CG-CD1 4.28Å; L544-Y598 HydrophobicContact CG-CE1 3.93Å; L544-Y598 HydrophobicContact CG-CE2 4.41Å; N545-Y598 WeakPolarHBondContact OD1-CE1 3.42Å; I548-Y598 HydrophobicContact CD1-CD1 3.34Å; I548-Y598 HydrophobicContact CD1-CE1 3.97Å; I548-Y598 HydrophobicContact CD1-CG 4.15Å; Y596-Y598 VanDerWaalsContact C-N 3.34Å; Y596-Y598 PolarHBondContact O-N 3.36Å; Y598-K601 WeakPolarHBondContact O-CB 3.4Å; Y598-K601 PolarHBondContact O-N 2.81Å; Y598-I602 WeakPolarHBondContact O-CB 3.33Å; Y598-I602 WeakPolarHBondContact O-CD1 3.42Å; Y598-I602 WeakPolarHBondContact O-CG1 2.89Å; Y598-I602 PolarHBondContact O-N 3.19Å
599	W	85	Confident	70.7	Confident	2 Å²	2	65.9 Å²	65.9	1%	0.008	33%	0.329	C	S	.	.	H	α-helix	trans	-63.9	-43.5	176.5	-74.6	117.1	0	0	0	112.7	F536 L569 N572 M573 Y596 K601 I602 L603 F638 L651	F536-W599 HydrophobicContact CB-CD2 4.44Å; F536-W599 HydrophobicContact CB-CZ2 4.06Å; F536-W599 AromaticContact CD2-CH2 3.59Å; F536-W599 HydrophobicContact CD2-CH2 3.59Å; F536-W599 AromaticContact CD2-CZ2 3.56Å; F536-W599 HydrophobicContact CD2-CZ2 3.56Å; F536-W599 HydrophobicContact CD2-CZ3 4.16Å; F536-W599 HydrophobicContact CE2-CH2 4.09Å; F536-W599 HydrophobicContact CE2-CZ2 4.48Å; F536-W599 HydrophobicContact CE2-CZ3 4.48Å; F536-W599 HydrophobicContact CG-CZ2 4.22Å; L569-W599 HydrophobicContact CD2-CZ3 4.12Å; N572-W599 HydrophobicContact CB-CH2 3.78Å; N572-W599 HydrophobicContact CB-CZ2 3.9Å; M573-W599 HydrophobicContact CB-CH2 4.43Å; M573-W599 HydrophobicContact CG-CE3 4.5Å; M573-W599 HydrophobicContact CG-CH2 3.41Å; M573-W599 VanDerWaalsContact CG-CH2 3.41Å; M573-W599 HydrophobicContact CG-CZ2 3.84Å; M573-W599 HydrophobicContact CG-CZ3 3.79Å; M573-W599 HydrophobicContact SD-CD2 3.89Å; M573-W599 VanDerWaalsContact SD-CE2 3.59Å; M573-W599 HydrophobicContact SD-CE3 3.98Å; M573-W599 HydrophobicContact SD-CH2 3.53Å; M573-W599 VanDerWaalsContact SD-CH2 3.53Å; M573-W599 HydrophobicContact SD-CZ2 3.39Å; M573-W599 WeakPolarHBondContact SD-CZ2 3.45Å; M573-W599 HydrophobicContact SD-CZ3 3.82Å; Y596-W599 WeakPolarHBondContact O-CB 3.47Å; Y596-W599 PolarHBondContact O-N 3.41Å; Y596-W599 VanDerWaalsContact O-N 3.15Å; W599-K601 VanDerWaalsContact C-N 3.33Å; W599-K601 PolarHBondContact O-N 3.01Å; W599-I602 HydrophobicContact CE3-CD1 4.14Å; W599-I602 HydrophobicContact CZ3-CD1 4.32Å; W599-I602 PolarHBondContact O-N 3.07Å; W599-L603 WeakPolarHBondContact O-CB 3.43Å; W599-L603 VanDerWaalsContact O-CG 3.26Å; W599-L603 WeakPolarHBondContact O-CG 2.91Å; W599-L603 PolarHBondContact O-N 2.77Å; W599-F638 HydrophobicContact CE3-CE2 4.41Å; W599-F638 HydrophobicContact CE3-CZ 4.44Å; W599-F638 HydrophobicContact CH2-CE2 4.3Å; W599-F638 AromaticContact CZ3-CE2 3.67Å; W599-F638 HydrophobicContact CZ3-CE2 3.67Å; W599-F638 HydrophobicContact CZ3-CZ 4.08Å; W599-L651 HydrophobicContact CB-CD1 3.57Å; W599-L651 HydrophobicContact CB-CD2 3.69Å; W599-L651 HydrophobicContact CB-CG 4.3Å; W599-L651 HydrophobicContact CD2-CD1 4.44Å; W599-L651 HydrophobicContact CG-CD1 3.83Å
600	I	84.8	Confident	73.2	Confident	44 Å²	44	59.2 Å²	59.2	23%	0.226	29%	0.294	C	S	.	.	H	α-helix	trans	-56.3	-50.5	173.9	-70.6	169.4	0	0	0	109.7	Y596 L597 I602 L603 T604 L650 L651 Y654	Y596-I600 WeakPolarHBondContact O-CG1 3.41Å; Y596-I600 PolarHBondContact O-N 3.06Å; L597-I600 PolarHBondContact O-N 2.96Å; I600-I602 PolarHBondContact O-N 3.47Å; I600-L603 PolarHBondContact O-N 3.16Å; I600-T604 PolarHBondContact O-N 3.18Å; I600-T604 PolarHBondContact O-OG1 2.74Å; I600-L650 HydrophobicContact CD1-CD2 3.94Å; I600-L650 HydrophobicContact CG1-CD2 4.45Å; I600-L651 HydrophobicContact CG1-CD2 3.96Å; I600-Y654 HydrophobicContact CG1-CD2 4.45Å; I600-Y654 HydrophobicContact CG1-CG 4.5Å; I600-Y654 HydrophobicContact CG2-CD2 4.21Å; I600-Y654 HydrophobicContact CG2-CE1 4.07Å; I600-Y654 HydrophobicContact CG2-CE2 3.65Å
601	K	84.9	Confident	75.4	Confident	55 Å²	55	56.9 Å²	56.9	24%	0.239	28%	0.282	C	S	.	.	H	α-helix	trans	-56.8	-48	177.2	-173.6	-179.8	-177.1	-174.7	0	111.6	N545 I548 D549 L597 Y598 W599 L603 T604 L605	N545-K601 PolarHBondContact OD1-NZ 3.3Å; I548-K601 HydrophobicContact CG2-CD 4.28Å; D549-K601 WeakPolarHBondContact OD1-CE 3.34Å; D549-K601 IonicContact OD1-NZ 2.78Å; D549-K601 PolarHBondContact OD1-NZ 2.94Å; D549-K601 IonicContact OD2-NZ 2.74Å; D549-K601 PolarHBondContact OD2-NZ 3.02Å; L597-K601 PolarHBondContact O-N 2.9Å; L597-K601 VanDerWaalsContact O-N 3.09Å; Y598-K601 WeakPolarHBondContact O-CB 3.4Å; Y598-K601 PolarHBondContact O-N 2.81Å; W599-K601 VanDerWaalsContact C-N 3.33Å; W599-K601 PolarHBondContact O-N 3.01Å; K601-L603 PolarHBondContact O-N 3.48Å; K601-T604 PolarHBondContact O-N 3.22Å; K601-L605 HydrophobicContact CG-CD1 3.99Å; K601-L605 WeakPolarHBondContact O-CB 3.23Å; K601-L605 WeakPolarHBondContact O-CG 3.47Å; K601-L605 PolarHBondContact O-N 3.45Å
602	I	87.3	Confident	77.3	Confident	3 Å²	3	58.4 Å²	58.4	2%	0.015	28%	0.284	C	S	.	.	H	α-helix	trans	-60.5	-44.3	178.4	-70.8	162.2	0	0	0	111.3	F536 I548 L569 Y598 W599 I600 L605 L606	F536-I602 HydrophobicContact CD1-CD1 3.74Å; F536-I602 HydrophobicContact CD2-CD1 4.09Å; F536-I602 HydrophobicContact CE1-CD1 3.54Å; F536-I602 HydrophobicContact CE2-CD1 3.89Å; F536-I602 HydrophobicContact CG-CD1 4.03Å; F536-I602 HydrophobicContact CZ-CD1 3.61Å; I548-I602 HydrophobicContact CD1-CD1 4.36Å; I548-I602 HydrophobicContact CD1-CG1 4.4Å; I548-I602 HydrophobicContact CG2-CG1 4.43Å; L569-I602 HydrophobicContact CD1-CG2 3.73Å; L569-I602 HydrophobicContact CD2-CD1 4.02Å; L569-I602 HydrophobicContact CD2-CG2 3.72Å; L569-I602 HydrophobicContact CG-CG2 4.38Å; Y598-I602 WeakPolarHBondContact O-CB 3.33Å; Y598-I602 WeakPolarHBondContact O-CD1 3.42Å; Y598-I602 WeakPolarHBondContact O-CG1 2.89Å; Y598-I602 PolarHBondContact O-N 3.19Å; W599-I602 HydrophobicContact CE3-CD1 4.14Å; W599-I602 HydrophobicContact CZ3-CD1 4.32Å; W599-I602 PolarHBondContact O-N 3.07Å; I600-I602 PolarHBondContact O-N 3.47Å; I602-L605 PolarHBondContact O-N 3.11Å; I602-L606 WeakPolarHBondContact O-CB 3.38Å; I602-L606 PolarHBondContact O-N 3.35Å
603	L	87.6	Confident	79.1	Confident	0 Å²	0	54.3 Å²	54.3	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-65.5	-42.1	-179.4	-71.7	170.5	0	0	0	112.2	W599 I600 K601 L605 L606 N607 F638 I642 L651 Y654 I655 L662	W599-L603 WeakPolarHBondContact O-CB 3.43Å; W599-L603 VanDerWaalsContact O-CG 3.26Å; W599-L603 WeakPolarHBondContact O-CG 2.91Å; W599-L603 PolarHBondContact O-N 2.77Å; I600-L603 PolarHBondContact O-N 3.16Å; K601-L603 PolarHBondContact O-N 3.48Å; L603-L605 VanDerWaalsContact C-N 3.35Å; L603-L606 PolarHBondContact O-N 2.85Å; L603-N607 VanDerWaalsContact O-CB 3.31Å; L603-N607 WeakPolarHBondContact O-CB 3.45Å; L603-N607 PolarHBondContact O-N 3.27Å; L603-F638 HydrophobicContact CD2-CE1 3.86Å; L603-F638 HydrophobicContact CD2-CZ 4.04Å; L603-I642 HydrophobicContact CD2-CD1 4.08Å; L603-L651 HydrophobicContact CD1-CB 4.15Å; L603-L651 HydrophobicContact CD1-CD1 4.47Å; L603-L651 HydrophobicContact CD1-CD2 3.95Å; L603-L651 HydrophobicContact CD1-CG 4.42Å; L603-Y654 HydrophobicContact CB-CD1 4.39Å; L603-Y654 HydrophobicContact CB-CE1 4.32Å; L603-Y654 HydrophobicContact CD1-CD1 4.32Å; L603-I655 HydrophobicContact CD1-CD1 4.18Å; L603-I655 HydrophobicContact CD1-CG1 3.97Å; L603-I655 HydrophobicContact CD2-CD1 4Å; L603-I655 HydrophobicContact CD2-CG1 4.18Å; L603-L662 HydrophobicContact CD2-CD1 3.88Å
604	T	86.9	Confident	80.9	Confident	49 Å²	49	47.7 Å²	47.7	30%	0.301	23%	0.231	S	C	.	.	H	α-helix	trans	-57.7	-50.5	173.6	-45.4	0	0	0	0	110.5	I600 K601 N607 D608 Y654	I600-T604 PolarHBondContact O-N 3.18Å; I600-T604 PolarHBondContact O-OG1 2.74Å; K601-T604 PolarHBondContact O-N 3.22Å; T604-N607 PolarHBondContact O-N 2.89Å; T604-D608 PolarHBondContact O-N 2.75Å; T604-D608 VanDerWaalsContact O-N 3.12Å; T604-Y654 PolarHBondContact OG1-OH 2.88Å
605	L	85	Confident	82.5	Confident	36 Å²	36	43.6 Å²	43.6	19%	0.188	22%	0.222	C	C	.	.	H	α-helix	trans	-63.8	-44.6	-178.2	-70.3	174	0	0	0	112.1	I548 L553 K601 I602 L603 N607 D608 H609	I548-L605 HydrophobicContact CG2-CD1 3.91Å; L553-L605 HydrophobicContact CD1-CD1 3.97Å; L553-L605 HydrophobicContact CD1-CD2 4.03Å; L553-L605 HydrophobicContact CD2-CB 3.63Å; L553-L605 HydrophobicContact CD2-CD1 3.62Å; L553-L605 HydrophobicContact CD2-CD2 3.87Å; L553-L605 HydrophobicContact CD2-CG 3.85Å; L553-L605 HydrophobicContact CG-CD1 3.94Å; K601-L605 HydrophobicContact CG-CD1 3.99Å; K601-L605 WeakPolarHBondContact O-CB 3.23Å; K601-L605 WeakPolarHBondContact O-CG 3.47Å; K601-L605 PolarHBondContact O-N 3.45Å; I602-L605 PolarHBondContact O-N 3.11Å; L603-L605 VanDerWaalsContact C-N 3.35Å; L605-N607 VanDerWaalsContact C-N 3.33Å; L605-N607 PolarHBondContact O-N 2.87Å; L605-D608 PolarHBondContact O-N 3.42Å; L605-H609 PolarHBondContact O-CD2 3.03Å; L605-H609 PolarHBondContact O-N 3.24Å
606	L	86.9	Confident	83.4	Confident	9 Å²	9	47 Å²	47	5%	0.047	23%	0.233	C	C	.	.	H	α-helix	trans	-60.9	-44.1	178.2	-175	67.7	0	0	0	111	F556 M566 I602 L603 D608 H609 L610 L635 F638 L662	F556-L606 HydrophobicContact CD2-CD1 4.34Å; F556-L606 HydrophobicContact CE1-CD1 4.09Å; F556-L606 HydrophobicContact CE2-CD1 3.57Å; F556-L606 HydrophobicContact CZ-CD1 3.42Å; F556-L606 VanDerWaalsContact CZ-CD1 3.42Å; M566-L606 HydrophobicContact CE-CD2 4.46Å; M566-L606 HydrophobicContact SD-CD1 3.67Å; M566-L606 HydrophobicContact SD-CD2 4.3Å; I602-L606 WeakPolarHBondContact O-CB 3.38Å; I602-L606 PolarHBondContact O-N 3.35Å; L603-L606 PolarHBondContact O-N 2.85Å; L606-D608 VanDerWaalsContact C-N 3.33Å; L606-D608 PolarHBondContact O-N 3.29Å; L606-H609 PolarHBondContact O-N 2.66Å; L606-L610 HydrophobicContact CD1-CD1 4.12Å; L606-L610 HydrophobicContact CD1-CG 4.16Å; L606-L610 HydrophobicContact CD2-CD1 4.39Å; L606-L610 HydrophobicContact CG-CD1 3.75Å; L606-L610 HydrophobicContact CG-CG 4.23Å; L606-L610 VanDerWaalsContact O-CB 3.27Å; L606-L610 WeakPolarHBondContact O-CB 3.21Å; L606-L610 WeakPolarHBondContact O-CG 3.28Å; L606-L610 PolarHBondContact O-N 3.31Å; L606-L635 HydrophobicContact CD2-CD1 3.85Å; L606-F638 HydrophobicContact CD2-CE1 4.14Å; L606-L662 HydrophobicContact CD2-CD1 4.24Å; L606-L662 HydrophobicContact CD2-CD2 3.93Å; L606-L662 HydrophobicContact CG-CD2 4.23Å
607	N	86.5	Confident	83.7	Confident	11 Å²	11	46.1 Å²	46.1	6%	0.059	23%	0.229	C	C	.	.	H	α-helix	trans	-59	-44	176.4	179.2	85.2	0	0	0	111.9	L603 T604 L605 C659 I661 L662	L603-N607 VanDerWaalsContact O-CB 3.31Å; L603-N607 WeakPolarHBondContact O-CB 3.45Å; L603-N607 PolarHBondContact O-N 3.27Å; T604-N607 PolarHBondContact O-N 2.89Å; L605-N607 VanDerWaalsContact C-N 3.33Å; L605-N607 PolarHBondContact O-N 2.87Å; N607-C659 HydrophobicContact CB-CB 4.02Å; N607-C659 WeakPolarHBondContact OD1-CA 3.12Å; N607-I661 VanDerWaalsContact O-CD1 3.31Å; N607-I661 WeakPolarHBondContact O-CD1 3.29Å; N607-I661 WeakPolarHBondContact OD1-CB 3.29Å; N607-I661 PolarHBondContact OD1-N 3.45Å; N607-L662 HydrophobicContact CB-CD1 4.19Å; N607-L662 HydrophobicContact CB-CG 4.22Å
608	D	84.2	Confident	83.6	Confident	96 Å²	96	44.9 Å²	44.9	51%	0.513	22%	0.219	S	C	.	.	H	α-helix	trans	-68.9	-40.7	-179	-69.3	-13.3	0	0	0	112.4	T604 L605 L606 P612	T604-D608 PolarHBondContact O-N 2.75Å; T604-D608 VanDerWaalsContact O-N 3.12Å; L605-D608 PolarHBondContact O-N 3.42Å; L606-D608 VanDerWaalsContact C-N 3.33Å; L606-D608 PolarHBondContact O-N 3.29Å; D608-P612 WeakPolarHBondContact O-CD 3.48Å
609	H	83.9	Confident	83.5	Confident	64 Å²	64	53.3 Å²	53.3	30%	0.296	25%	0.252	S	S	.	.	H	α-helix	trans	-79	-27.6	-178.9	-76.8	-72	0	0	0	114.3	L553 F556 L605 L606 K611 P612 Q613	L553-H609 WeakPolarHBondContact CD2-NE2 3.26Å; F556-H609 HydrophobicContact CD1-CB 3.61Å; F556-H609 HydrophobicContact CE1-CB 3.74Å; L605-H609 PolarHBondContact O-CD2 3.03Å; L605-H609 PolarHBondContact O-N 3.24Å; L606-H609 PolarHBondContact O-N 2.66Å; H609-K611 VanDerWaalsContact C-N 3.3Å; H609-K611 PolarHBondContact O-N 3.4Å; H609-P612 VanDerWaalsContact O-CD 3.26Å; H609-P612 WeakPolarHBondContact O-CD 3.36Å; H609-P612 WeakPolarHBondContact O-CG 3.38Å; H609-Q613 WeakPolarHBondContact O-CG 3.36Å
610	L	84.2	Confident	83.2	Confident	1 Å²	1	54.9 Å²	54.9	1%	0.005	26%	0.261	C	S	.	.	H	α-helix	trans	-66.6	-31.3	176.2	-81.4	170.8	0	0	0	112.3	F556 L606 Q613 L614 L635 I661 L662 L665	F556-L610 HydrophobicContact CE1-CD2 4.29Å; F556-L610 HydrophobicContact CE1-CG 4.33Å; F556-L610 HydrophobicContact CZ-CD2 3.78Å; F556-L610 HydrophobicContact CZ-CG 4.08Å; L606-L610 HydrophobicContact CD1-CD1 4.12Å; L606-L610 HydrophobicContact CD1-CG 4.16Å; L606-L610 HydrophobicContact CD2-CD1 4.39Å; L606-L610 HydrophobicContact CG-CD1 3.75Å; L606-L610 HydrophobicContact CG-CG 4.23Å; L606-L610 VanDerWaalsContact O-CB 3.27Å; L606-L610 WeakPolarHBondContact O-CB 3.21Å; L606-L610 WeakPolarHBondContact O-CG 3.28Å; L606-L610 PolarHBondContact O-N 3.31Å; L610-Q613 PolarHBondContact O-N 2.97Å; L610-L614 HydrophobicContact CB-CD1 4.27Å; L610-L614 WeakPolarHBondContact O-CB 3.3Å; L610-L614 VanDerWaalsContact O-CG 3.26Å; L610-L614 WeakPolarHBondContact O-CG 3.21Å; L610-L614 PolarHBondContact O-N 3.44Å; L610-L635 HydrophobicContact CD1-CD1 4.23Å; L610-L635 HydrophobicContact CD1-CD2 3.83Å; L610-L635 HydrophobicContact CD2-CD2 3.98Å; L610-I661 HydrophobicContact CB-CG2 4.27Å; L610-L662 HydrophobicContact CD1-CD2 3.38Å; L610-L662 HydrophobicContact CD1-CG 4.42Å; L610-L665 HydrophobicContact CD1-CD1 4.14Å
611	K	81.3	Confident	82.6	Confident	129 Å²	129	58.9 Å²	58.9	56%	0.561	28%	0.276	S	S	*	.	H	α-helix	trans	-53.7	-57.8	-178.6	-164.8	179.7	180	176.9	0	113.5	H609 Q613 I615 I661	H609-K611 VanDerWaalsContact C-N 3.3Å; H609-K611 PolarHBondContact O-N 3.4Å; K611-Q613 VanDerWaalsContact C-N 3.3Å; K611-Q613 PolarHBondContact O-N 3.48Å; K611-I615 WeakPolarHBondContact O-CG1 3.48Å; K611-I615 PolarHBondContact O-N 3.02Å; K611-I661 HydrophobicContact CB-CD1 3.45Å; K611-I661 VanDerWaalsContact CB-CD1 3.45Å; K611-I661 HydrophobicContact CD-CD1 4.08Å; K611-I661 HydrophobicContact CG-CD1 3.77Å
612	P	81.8	Confident	81.8	Confident	78 Å²	78	64.9 Å²	64.9	51%	0.506	31%	0.305	S	S	.	.	H	α-helix	trans	-65.8	-32.8	178.3	26.7	-36.1	0	0	0	112.6	D608 H609 I615 Y616	D608-P612 WeakPolarHBondContact O-CD 3.48Å; H609-P612 VanDerWaalsContact O-CD 3.26Å; H609-P612 WeakPolarHBondContact O-CD 3.36Å; H609-P612 WeakPolarHBondContact O-CG 3.38Å; P612-I615 PolarHBondContact O-N 3.28Å; P612-Y616 WeakPolarHBondContact O-CB 3.48Å; P612-Y616 PolarHBondContact O-N 3.27Å
613	Q	82.6	Confident	81.1	Confident	24 Å²	24	71.3 Å²	71.3	11%	0.112	34%	0.34	C	S	.	.	H	α-helix	trans	-67.6	-45.3	179.5	-71.3	-175.2	-11.3	0	0	112.5	F556 H609 L610 K611 I615 Y616 W617	F556-Q613 VanDerWaalsContact CZ-OE1 3.31Å; F556-Q613 PolarHBondContact O-NE2 2.9Å; H609-Q613 WeakPolarHBondContact O-CG 3.36Å; L610-Q613 PolarHBondContact O-N 2.97Å; K611-Q613 VanDerWaalsContact C-N 3.3Å; K611-Q613 PolarHBondContact O-N 3.48Å; Q613-I615 VanDerWaalsContact C-N 3.3Å; Q613-I615 PolarHBondContact O-N 3.49Å; Q613-Y616 CarbonylContact O-C 3.51Å; Q613-Y616 WeakPolarHBondContact O-CA 3.29Å; Q613-Y616 WeakPolarHBondContact O-CB 3.2Å; Q613-Y616 PolarHBondContact O-N 3.49Å; Q613-Y616 VanDerWaalsContact O-N 3.09Å; Q613-W617 HydrophobicContact CB-CH2 4.48Å; Q613-W617 HydrophobicContact CB-CZ2 4.1Å; Q613-W617 WeakPolarHBondContact O-CB 3.4Å; Q613-W617 PolarHBondContact O-N 3.35Å
614	L	81.6	Confident	80.5	Confident	12 Å²	12	72.2 Å²	72.2	6%	0.063	35%	0.345	C	S	.	.	H	α-helix	trans	-61.9	-39.3	177.2	-70	168.1	0	0	0	111.4	L610 Y616 W617 K618 L632 I661 L665 L710 I713	L610-L614 HydrophobicContact CB-CD1 4.27Å; L610-L614 WeakPolarHBondContact O-CB 3.3Å; L610-L614 VanDerWaalsContact O-CG 3.26Å; L610-L614 WeakPolarHBondContact O-CG 3.21Å; L610-L614 PolarHBondContact O-N 3.44Å; L614-Y616 VanDerWaalsContact C-N 3.33Å; L614-Y616 PolarHBondContact O-N 3.13Å; L614-W617 HydrophobicContact CD2-CE3 3.93Å; L614-W617 HydrophobicContact CD2-CZ3 4.15Å; L614-W617 PolarHBondContact O-N 3.49Å; L614-K618 VanDerWaalsContact O-CB 3.24Å; L614-K618 WeakPolarHBondContact O-CB 3.23Å; L614-K618 PolarHBondContact O-N 3.15Å; L614-L632 HydrophobicContact CD2-CD2 4.27Å; L614-I661 HydrophobicContact CD1-CG2 3.62Å; L614-L665 HydrophobicContact CD1-CD1 4.14Å; L614-L710 HydrophobicContact CD2-CD2 3.6Å; L614-I713 HydrophobicContact CD1-CG2 4.38Å
615	I	80	Confident	80.1	Confident	113 Å²	113	71.8 Å²	71.8	58%	0.579	34%	0.342	S	S	*	.	H	α-helix	trans	-60.7	-45.1	173.4	-65.9	166.9	0	0	0	110.4	K611 P612 Q613 K618 Y619	K611-I615 WeakPolarHBondContact O-CG1 3.48Å; K611-I615 PolarHBondContact O-N 3.02Å; P612-I615 PolarHBondContact O-N 3.28Å; Q613-I615 VanDerWaalsContact C-N 3.3Å; Q613-I615 PolarHBondContact O-N 3.49Å; I615-K618 PolarHBondContact O-N 3.37Å; I615-Y619 PolarHBondContact O-N 3.4Å; I615-Y619 VanDerWaalsContact O-N 3.08Å
616	Y	81.2	Confident	79.8	Confident	119 Å²	119	73.7 Å²	73.7	47%	0.467	35%	0.352	S	S	.	.	H	α-helix	trans	-65.1	-43.5	178	178.7	-111.2	0	0	0	112.5	P612 Q613 L614 Y619 L620 Y628	P612-Y616 WeakPolarHBondContact O-CB 3.48Å; P612-Y616 PolarHBondContact O-N 3.27Å; Q613-Y616 CarbonylContact O-C 3.51Å; Q613-Y616 WeakPolarHBondContact O-CA 3.29Å; Q613-Y616 WeakPolarHBondContact O-CB 3.2Å; Q613-Y616 PolarHBondContact O-N 3.49Å; Q613-Y616 VanDerWaalsContact O-N 3.09Å; L614-Y616 VanDerWaalsContact C-N 3.33Å; L614-Y616 PolarHBondContact O-N 3.13Å; Y616-Y619 WeakPolarHBondContact O-CB 3.35Å; Y616-Y619 PolarHBondContact O-N 3.14Å; Y616-Y619 VanDerWaalsContact O-N 3.16Å; Y616-L620 HydrophobicContact CD1-CD1 4.19Å; Y616-L620 HydrophobicContact CE1-CD1 3.65Å; Y616-L620 HydrophobicContact CE1-CG 4.38Å; Y616-L620 PolarHBondContact O-N 3.28Å; Y616-L620 VanDerWaalsContact O-N 3.13Å; Y616-Y628 HydrophobicContact CE1-CE2 4.21Å
617	W	80.9	Confident	79.5	Confident	2 Å²	2	74 Å²	74	1%	0.008	35%	0.354	C	S	.	.	H	α-helix	trans	-65.8	-39.4	177.2	-61.6	-14.8	0	0	0	112	Q613 L614 Y619 L620 K621 L624 Y628 T631 L632 L710	Q613-W617 HydrophobicContact CB-CH2 4.48Å; Q613-W617 HydrophobicContact CB-CZ2 4.1Å; Q613-W617 WeakPolarHBondContact O-CB 3.4Å; Q613-W617 PolarHBondContact O-N 3.35Å; L614-W617 HydrophobicContact CD2-CE3 3.93Å; L614-W617 HydrophobicContact CD2-CZ3 4.15Å; L614-W617 PolarHBondContact O-N 3.49Å; W617-Y619 VanDerWaalsContact C-N 3.25Å; W617-Y619 PolarHBondContact O-N 3.42Å; W617-L620 PolarHBondContact O-N 3.48Å; W617-L620 VanDerWaalsContact O-N 3.11Å; W617-K621 PolarHBondContact O-N 2.98Å; W617-L624 HydrophobicContact CB-CD1 3.73Å; W617-L624 HydrophobicContact CG-CD1 3.9Å; W617-Y628 AromaticContact CD1-CD2 3.66Å; W617-Y628 AromaticContact CD1-CE2 3.88Å; W617-Y628 AromaticContact CD1-CG 3.78Å; W617-Y628 HydrophobicContact CD2-CD1 4.42Å; W617-Y628 HydrophobicContact CD2-CG 4.29Å; W617-Y628 AromaticContact CE2-CD1 3.33Å; W617-Y628 AromaticContact CE2-CE1 3.81Å; W617-Y628 AromaticContact CE2-CG 3.6Å; W617-Y628 HydrophobicContact CG-CG 4.41Å; W617-Y628 HydrophobicContact CH2-CD1 4.48Å; W617-Y628 AromaticContact CZ2-CD1 3.37Å; W617-Y628 HydrophobicContact CZ2-CD1 3.37Å; W617-Y628 AromaticContact CZ2-CE1 3.94Å; W617-Y628 HydrophobicContact CZ2-CE1 3.94Å; W617-Y628 HydrophobicContact CZ2-CG 4.01Å; W617-Y628 AromaticContact NE1-CD1 3.07Å; W617-Y628 AromaticContact NE1-CD2 3.51Å; W617-Y628 AromaticContact NE1-CE1 3.17Å; W617-Y628 AromaticContact NE1-CE2 3.66Å; W617-Y628 AromaticContact NE1-CG 3.24Å; W617-Y628 AromaticContact NE1-CZ 3.49Å; W617-T631 HydrophobicContact CH2-CG2 3.88Å; W617-T631 HydrophobicContact CZ2-CG2 4.47Å; W617-L632 HydrophobicContact CE3-CD1 3.92Å; W617-L632 HydrophobicContact CE3-CD2 4.07Å; W617-L632 HydrophobicContact CE3-CG 4Å; W617-L632 HydrophobicContact CZ3-CD1 4.08Å; W617-L632 HydrophobicContact CZ3-CD2 3.59Å; W617-L632 HydrophobicContact CZ3-CG 3.61Å; W617-L710 HydrophobicContact CB-CD1 4.29Å; W617-L710 HydrophobicContact CE3-CD2 4.41Å
618	K	77.9	Confident	79.3	Confident	84 Å²	84	74.3 Å²	74.3	37%	0.365	36%	0.355	S	S	.	.	H	α-helix	trans	-60.6	-34.7	172.2	-171.4	170.3	-166.1	155.5	0	112.2	L614 I615 K621 E711 I713	L614-K618 VanDerWaalsContact O-CB 3.24Å; L614-K618 WeakPolarHBondContact O-CB 3.23Å; L614-K618 PolarHBondContact O-N 3.15Å; I615-K618 PolarHBondContact O-N 3.37Å; K618-K621 WeakPolarHBondContact O-CG 3.35Å; K618-E711 PolarHBondContact NZ-O 2.94Å; K618-I713 PolarHBondContact NZ-OXT 3.18Å
619	Y	78.7	Confident	79	Confident	188 Å²	188	70 Å²	70	74%	0.737	33%	0.332	S	S	*	.	H	α-helix	trans	-68.1	-37.5	173.7	178.4	-94.9	0	0	0	112.6	I615 Y616 W617 K621	I615-Y619 PolarHBondContact O-N 3.4Å; I615-Y619 VanDerWaalsContact O-N 3.08Å; Y616-Y619 WeakPolarHBondContact O-CB 3.35Å; Y616-Y619 PolarHBondContact O-N 3.14Å; Y616-Y619 VanDerWaalsContact O-N 3.16Å; W617-Y619 VanDerWaalsContact C-N 3.25Å; W617-Y619 PolarHBondContact O-N 3.42Å; Y619-K621 VanDerWaalsContact C-N 3.29Å; Y619-K621 PolarHBondContact O-N 3.33Å
620	L	77.9	Confident	78.8	Confident	35 Å²	35	67.4 Å²	67.4	18%	0.183	32%	0.32	C	S	.	.	H	α-helix	trans	-67.8	-26.9	178.9	-68.1	174.3	0	0	0	113.2	Y616 W617 Q622 N623 L624 Y628	Y616-L620 HydrophobicContact CD1-CD1 4.19Å; Y616-L620 HydrophobicContact CE1-CD1 3.65Å; Y616-L620 HydrophobicContact CE1-CG 4.38Å; Y616-L620 PolarHBondContact O-N 3.28Å; Y616-L620 VanDerWaalsContact O-N 3.13Å; W617-L620 PolarHBondContact O-N 3.48Å; W617-L620 VanDerWaalsContact O-N 3.11Å; L620-Q622 PolarHBondContact O-N 3.45Å; L620-Q622 VanDerWaalsContact O-N 3.07Å; L620-N623 PolarHBondContact O-N 3.05Å; L620-L624 HydrophobicContact CB-CD1 4.33Å; L620-L624 HydrophobicContact CD1-CD1 4.16Å; L620-Y628 HydrophobicContact CD1-CD2 4.33Å; L620-Y628 HydrophobicContact CD1-CE2 4Å
621	K	72.5	Confident	78.9	Confident	128 Å²	128	67.5 Å²	67.5	56%	0.557	32%	0.32	S	S	*	.	G	3₁₀ helix	trans	45.4	-111.2	179.6	-63	-169	176.5	-166.9	0	112.4	W617 K618 Y619 N623	W617-K621 PolarHBondContact O-N 2.98Å; K618-K621 WeakPolarHBondContact O-CG 3.35Å; Y619-K621 VanDerWaalsContact C-N 3.29Å; Y619-K621 PolarHBondContact O-N 3.33Å; K621-N623 VanDerWaalsContact C-N 3.26Å; K621-N623 PolarHBondContact O-N 3.49Å
622	Q	67.8	Low	79	Confident	182 Å²	182	61.4 Å²	61.4	85%	0.85	29%	0.294	S	S	*	.	G	3₁₀ helix	trans	-73.4	-15.5	-176.4	-65.3	179	-6.9	0	0	113.5	L620 L624	L620-Q622 PolarHBondContact O-N 3.45Å; L620-Q622 VanDerWaalsContact O-N 3.07Å; Q622-L624 VanDerWaalsContact C-N 3.34Å
623	N	73.5	Confident	79	Confident	137 Å²	137	57.7 Å²	57.7	73%	0.733	27%	0.27	S	S	*	.	G	3₁₀ helix	trans	-96.7	23.1	179.4	-68.2	-24.3	0	0	0	112.3	L620 K621 P625	L620-N623 PolarHBondContact O-N 3.05Å; K621-N623 VanDerWaalsContact C-N 3.26Å; K621-N623 PolarHBondContact O-N 3.49Å; N623-P625 WeakPolarHBondContact O-CD 3.49Å
624	L	75.2	Confident	79	Confident	20 Å²	20	56.6 Å²	56.6	11%	0.105	27%	0.265	C	S	.	.			trans	-66	119.6	-178.9	-168.4	71.5	0	0	0	110.8	W617 L620 Q622 Y628 I629 L710	W617-L624 HydrophobicContact CB-CD1 3.73Å; W617-L624 HydrophobicContact CG-CD1 3.9Å; L620-L624 HydrophobicContact CB-CD1 4.33Å; L620-L624 HydrophobicContact CD1-CD1 4.16Å; Q622-L624 VanDerWaalsContact C-N 3.34Å; L624-Y628 HydrophobicContact CD1-CD2 3.68Å; L624-Y628 HydrophobicContact CD1-CG 4.18Å; L624-Y628 HydrophobicContact CG-CD2 4.34Å; L624-I629 HydrophobicContact CD2-CG1 3.69Å; L624-I629 HydrophobicContact CG-CG1 4.25Å; L624-L710 HydrophobicContact CD2-CD1 4.02Å
625	P	78.6	Confident	79.3	Confident	39 Å²	39	56.1 Å²	56.1	25%	0.253	26%	0.262	S	S	.	.			trans	-54	143.3	171.6	-30.3	35.8	0	0	0	113.6	E559 N623 C627 Y628 I629	E559-P625 WeakPolarHBondContact OE1-CB 3.25Å; E559-P625 WeakPolarHBondContact OE1-CG 3.29Å; N623-P625 WeakPolarHBondContact O-CD 3.49Å; P625-C627 VanDerWaalsContact CB-SG 3.57Å; P625-C627 PolarHBondContact O-N 3.46Å; P625-C627 VanDerWaalsContact O-N 3.15Å; P625-Y628 HydrophobicContact CB-CD2 3.96Å; P625-Y628 HydrophobicContact CB-CE2 4.21Å; P625-Y628 HydrophobicContact CG-CD2 3.89Å; P625-Y628 HydrophobicContact CG-CE2 3.82Å; P625-Y628 PolarHBondContact O-N 2.8Å; P625-I629 PolarHBondContact O-N 3.35Å
626	I	79	Confident	79.5	Confident	77 Å²	77	50.8 Å²	50.8	40%	0.395	24%	0.235	S	C	.	.	H	α-helix	trans	-53.5	-37.1	179.4	-64.7	172.4	0	0	0	111.7	Y628 I629 E630 L692	I626-Y628 VanDerWaalsContact C-N 3.31Å; I626-Y628 PolarHBondContact O-N 3.13Å; I626-I629 WeakPolarHBondContact O-CB 3.46Å; I626-I629 PolarHBondContact O-N 2.91Å; I626-I629 VanDerWaalsContact O-N 3.15Å; I626-E630 HydrophobicContact CG2-CG 4.31Å; I626-E630 WeakPolarHBondContact O-CG 3.37Å; I626-E630 PolarHBondContact O-N 2.7Å; I626-L692 HydrophobicContact CG2-CD1 4.26Å
627	C	79.8	Confident	79.6	Confident	14 Å²	14	45.6 Å²	45.6	10%	0.095	22%	0.215	C	C	.	.	H	α-helix	trans	-61.7	-33.7	179.7	53.7	0	0	0	0	113.7	E559 L560 P625 T631	E559-C627 WeakPolarHBondContact CG-SG 3.1Å; L560-C627 HydrophobicContact CD2-CB 3.93Å; P625-C627 VanDerWaalsContact CB-SG 3.57Å; P625-C627 PolarHBondContact O-N 3.46Å; P625-C627 VanDerWaalsContact O-N 3.15Å; C627-T631 WeakPolarHBondContact O-CB 3.37Å; C627-T631 PolarHBondContact O-N 3.48Å; C627-T631 PolarHBondContact O-OG1 3.01Å
628	Y	82.7	Confident	79.9	Confident	18 Å²	18	45.5 Å²	45.5	7%	0.071	22%	0.215	C	C	.	.	H	α-helix	trans	-75	-33.7	175.9	-62.5	-45.8	0	0	0	112	E559 Y616 W617 L620 L624 P625 I626 T631 L632	E559-Y628 HydrophobicContact CB-CE1 4.15Å; E559-Y628 WeakPolarHBondContact CB-OH 3.39Å; E559-Y628 HydrophobicContact CG-CE1 3.88Å; E559-Y628 HydrophobicContact CG-CE2 4.14Å; E559-Y628 WeakPolarHBondContact CG-OH 3.46Å; Y616-Y628 HydrophobicContact CE1-CE2 4.21Å; W617-Y628 AromaticContact CD1-CD2 3.66Å; W617-Y628 AromaticContact CD1-CE2 3.88Å; W617-Y628 AromaticContact CD1-CG 3.78Å; W617-Y628 HydrophobicContact CD2-CD1 4.42Å; W617-Y628 HydrophobicContact CD2-CG 4.29Å; W617-Y628 AromaticContact CE2-CD1 3.33Å; W617-Y628 AromaticContact CE2-CE1 3.81Å; W617-Y628 AromaticContact CE2-CG 3.6Å; W617-Y628 HydrophobicContact CG-CG 4.41Å; W617-Y628 HydrophobicContact CH2-CD1 4.48Å; W617-Y628 AromaticContact CZ2-CD1 3.37Å; W617-Y628 HydrophobicContact CZ2-CD1 3.37Å; W617-Y628 AromaticContact CZ2-CE1 3.94Å; W617-Y628 HydrophobicContact CZ2-CE1 3.94Å; W617-Y628 HydrophobicContact CZ2-CG 4.01Å; W617-Y628 AromaticContact NE1-CD1 3.07Å; W617-Y628 AromaticContact NE1-CD2 3.51Å; W617-Y628 AromaticContact NE1-CE1 3.17Å; W617-Y628 AromaticContact NE1-CE2 3.66Å; W617-Y628 AromaticContact NE1-CG 3.24Å; W617-Y628 AromaticContact NE1-CZ 3.49Å; L620-Y628 HydrophobicContact CD1-CD2 4.33Å; L620-Y628 HydrophobicContact CD1-CE2 4Å; L624-Y628 HydrophobicContact CD1-CD2 3.68Å; L624-Y628 HydrophobicContact CD1-CG 4.18Å; L624-Y628 HydrophobicContact CG-CD2 4.34Å; P625-Y628 HydrophobicContact CB-CD2 3.96Å; P625-Y628 HydrophobicContact CB-CE2 4.21Å; P625-Y628 HydrophobicContact CG-CD2 3.89Å; P625-Y628 HydrophobicContact CG-CE2 3.82Å; P625-Y628 PolarHBondContact O-N 2.8Å; I626-Y628 VanDerWaalsContact C-N 3.31Å; I626-Y628 PolarHBondContact O-N 3.13Å; Y628-T631 WeakPolarHBondContact O-CB 3.13Å; Y628-T631 PolarHBondContact O-N 3.45Å; Y628-L632 PolarHBondContact O-N 2.7Å
629	I	77.9	Confident	80.2	Confident	6 Å²	6	41.8 Å²	41.8	3%	0.031	20%	0.198	C	C	.	.	H	α-helix	trans	-60.4	-49.1	171.2	-58.8	176.7	0	0	0	109.5	L624 P625 I626 T631 L632 I633 L692 T703 I706	L624-I629 HydrophobicContact CD2-CG1 3.69Å; L624-I629 HydrophobicContact CG-CG1 4.25Å; P625-I629 PolarHBondContact O-N 3.35Å; I626-I629 WeakPolarHBondContact O-CB 3.46Å; I626-I629 PolarHBondContact O-N 2.91Å; I626-I629 VanDerWaalsContact O-N 3.15Å; I629-T631 VanDerWaalsContact C-N 3.3Å; I629-T631 PolarHBondContact O-N 3.37Å; I629-L632 PolarHBondContact O-N 2.79Å; I629-I633 HydrophobicContact CG2-CD1 4.06Å; I629-I633 WeakPolarHBondContact O-CG1 2.91Å; I629-I633 PolarHBondContact O-N 2.71Å; I629-L692 HydrophobicContact CB-CD1 4.37Å; I629-L692 HydrophobicContact CD1-CD2 4.39Å; I629-L692 HydrophobicContact CG2-CD1 3.79Å; I629-L692 HydrophobicContact CG2-CD2 3.74Å; I629-L692 HydrophobicContact CG2-CG 4.44Å; I629-T703 HydrophobicContact CD1-CG2 3.82Å; I629-I706 HydrophobicContact CG2-CD1 3.44Å; I629-I706 VanDerWaalsContact CG2-CD1 3.44Å
630	E	80.5	Confident	80.2	Confident	10 Å²	10	33.2 Å²	33.2	5%	0.047	17%	0.166	C	C	.	.	H	α-helix	trans	-59.6	-40.4	175	-67.9	176.7	126	0	0	112.2	K563 I626 I633 L634 M685 Q689 L692	K563-E630 HydrophobicContact CD-CB 4.33Å; K563-E630 VanDerWaalsContact CD-OE2 3.26Å; K563-E630 WeakPolarHBondContact CD-OE2 3.37Å; K563-E630 WeakPolarHBondContact CE-OE2 3.25Å; K563-E630 HydrophobicContact CG-CB 4.35Å; K563-E630 IonicContact NZ-OE1 3.01Å; K563-E630 PolarHBondContact NZ-OE1 2.99Å; K563-E630 IonicContact NZ-OE2 2.72Å; K563-E630 PolarHBondContact NZ-OE2 3.39Å; I626-E630 HydrophobicContact CG2-CG 4.31Å; I626-E630 WeakPolarHBondContact O-CG 3.37Å; I626-E630 PolarHBondContact O-N 2.7Å; E630-I633 PolarHBondContact O-N 3.47Å; E630-L634 WeakPolarHBondContact O-CG 3.34Å; E630-L634 PolarHBondContact O-N 3.16Å; E630-M685 HydrophobicContact CB-CE 4.12Å; E630-M685 HydrophobicContact CG-CE 4.26Å; E630-Q689 VanDerWaalsContact OE1-CG 3.27Å; E630-Q689 WeakPolarHBondContact OE1-CG 3.41Å; E630-Q689 PolarHBondContact OE1-NE2 2.91Å; E630-L692 HydrophobicContact CG-CD1 4.31Å
631	T	84.6	Confident	80.3	Confident	2 Å²	2	32.8 Å²	32.8	1%	0.012	16%	0.163	C	C	.	.	H	α-helix	trans	-61.1	-45.1	177.2	-56.8	0	0	0	0	111.3	A562 K563 M566 W617 C627 Y628 I629 L634 L635	A562-T631 HydrophobicContact CB-CG2 3.92Å; K563-T631 WeakPolarHBondContact CA-OG1 3.45Å; K563-T631 PolarHBondContact N-OG1 3.41Å; M566-T631 HydrophobicContact CB-CG2 4.44Å; M566-T631 HydrophobicContact CG-CG2 3.72Å; W617-T631 HydrophobicContact CH2-CG2 3.88Å; W617-T631 HydrophobicContact CZ2-CG2 4.47Å; C627-T631 WeakPolarHBondContact O-CB 3.37Å; C627-T631 PolarHBondContact O-N 3.48Å; C627-T631 PolarHBondContact O-OG1 3.01Å; Y628-T631 WeakPolarHBondContact O-CB 3.13Å; Y628-T631 PolarHBondContact O-N 3.45Å; I629-T631 VanDerWaalsContact C-N 3.3Å; I629-T631 PolarHBondContact O-N 3.37Å; T631-L634 PolarHBondContact O-N 2.75Å; T631-L635 WeakPolarHBondContact O-CB 3.49Å; T631-L635 PolarHBondContact O-N 2.98Å
632	L	83.5	Confident	80.6	Confident	1 Å²	1	27 Å²	27	1%	0.005	14%	0.138	C	C	.	.	H	α-helix	trans	-64.5	-41.7	177.2	-77.6	166.4	0	0	0	111.9	L614 W617 Y628 I629 L634 L635 F636 I706 L710	L614-L632 HydrophobicContact CD2-CD2 4.27Å; W617-L632 HydrophobicContact CE3-CD1 3.92Å; W617-L632 HydrophobicContact CE3-CD2 4.07Å; W617-L632 HydrophobicContact CE3-CG 4Å; W617-L632 HydrophobicContact CZ3-CD1 4.08Å; W617-L632 HydrophobicContact CZ3-CD2 3.59Å; W617-L632 HydrophobicContact CZ3-CG 3.61Å; Y628-L632 PolarHBondContact O-N 2.7Å; I629-L632 PolarHBondContact O-N 2.79Å; L632-L634 PolarHBondContact O-N 3.01Å; L632-L635 HydrophobicContact CD2-CD2 4.48Å; L632-L635 WeakPolarHBondContact O-CB 3.4Å; L632-L635 PolarHBondContact O-N 3.48Å; L632-F636 HydrophobicContact CB-CE2 4.14Å; L632-F636 HydrophobicContact CD2-CZ 4.5Å; L632-F636 WeakPolarHBondContact O-CD2 3.33Å; L632-F636 WeakPolarHBondContact O-CG 3.44Å; L632-F636 PolarHBondContact O-N 3.44Å; L632-I706 HydrophobicContact CB-CG2 4.36Å; L632-I706 HydrophobicContact CD1-CG2 3.43Å; L632-I706 VanDerWaalsContact CD1-CG2 3.43Å; L632-L710 HydrophobicContact CD1-CD1 3.88Å; L632-L710 HydrophobicContact CD1-CD2 3.97Å; L632-L710 HydrophobicContact CD1-CG 4.08Å; L632-L710 HydrophobicContact CD2-CD2 4.48Å
633	I	81.5	Confident	80.9	Confident	0 Å²	0	20.3 Å²	20.3	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-61.9	-45	176.7	-67.3	168.6	0	0	0	111	I629 E630 L635 F636 K637 L680 I688 L692 I702 I706	I629-I633 HydrophobicContact CG2-CD1 4.06Å; I629-I633 WeakPolarHBondContact O-CG1 2.91Å; I629-I633 PolarHBondContact O-N 2.71Å; E630-I633 PolarHBondContact O-N 3.47Å; I633-L635 VanDerWaalsContact C-N 3.3Å; I633-L635 PolarHBondContact O-N 3.26Å; I633-F636 PolarHBondContact O-N 3.18Å; I633-K637 HydrophobicContact CG2-CD 4.5Å; I633-K637 WeakPolarHBondContact O-CG 3.24Å; I633-K637 PolarHBondContact O-N 3.48Å; I633-L680 HydrophobicContact CB-CD2 4.31Å; I633-L680 HydrophobicContact CG1-CD2 4.27Å; I633-L680 HydrophobicContact CG2-CD2 3.75Å; I633-L680 HydrophobicContact CG2-CG 4.24Å; I633-I688 HydrophobicContact CD1-CG2 3.41Å; I633-I688 VanDerWaalsContact CD1-CG2 3.41Å; I633-I688 HydrophobicContact CG2-CD1 3.5Å; I633-I688 HydrophobicContact CG2-CG1 4.38Å; I633-L692 HydrophobicContact CD1-CD1 4.48Å; I633-I702 HydrophobicContact CD1-CG2 4.03Å; I633-I706 HydrophobicContact CD1-CD1 3.86Å; I633-I706 HydrophobicContact CG1-CD1 3.63Å
634	L	84.4	Confident	80.8	Confident	1 Å²	1	18.4 Å²	18.4	1%	0.005	10%	0.096	C	C	.	.	H	α-helix	trans	-62.7	-37.2	175.3	-73.2	166.3	0	0	0	112.1	K563 M566 F567 Y570 E630 T631 L632 K637 F638 M685	K563-L634 HydrophobicContact CG-CD1 4.12Å; M566-L634 HydrophobicContact CB-CB 3.8Å; M566-L634 HydrophobicContact CB-CD1 4.28Å; F567-L634 HydrophobicContact CB-CD1 3.88Å; F567-L634 HydrophobicContact CB-CD2 4.4Å; F567-L634 HydrophobicContact CD2-CD2 3.87Å; Y570-L634 HydrophobicContact CD1-CD2 4.28Å; Y570-L634 HydrophobicContact CG-CD2 4.47Å; E630-L634 WeakPolarHBondContact O-CG 3.34Å; E630-L634 PolarHBondContact O-N 3.16Å; T631-L634 PolarHBondContact O-N 2.75Å; L632-L634 PolarHBondContact O-N 3.01Å; L634-K637 PolarHBondContact O-N 3.49Å; L634-F638 VanDerWaalsContact O-CB 3.25Å; L634-F638 WeakPolarHBondContact O-CB 3.16Å; L634-F638 PolarHBondContact O-N 3.33Å; L634-M685 HydrophobicContact CD1-CE 4.19Å; L634-M685 HydrophobicContact CD2-CE 4.24Å; L634-M685 HydrophobicContact CD2-CG 4.29Å; L634-M685 HydrophobicContact CD2-SD 3.65Å; L634-M685 HydrophobicContact CG-CE 4.04Å; L634-M685 HydrophobicContact CG-SD 3.97Å
635	L	87.2	Confident	80.4	Confident	2 Å²	2	17.7 Å²	17.7	1%	0.01	9%	0.092	C	C	.	.	H	α-helix	trans	-64	-44.8	174.2	-178.6	64.8	0	0	0	112.4	M566 L606 L610 T631 L632 I633 F638 L639 L662 L665	M566-L635 HydrophobicContact CE-CB 3.91Å; M566-L635 HydrophobicContact CE-CD1 3.54Å; M566-L635 HydrophobicContact CE-CG 4.35Å; M566-L635 HydrophobicContact SD-CD1 4.21Å; L606-L635 HydrophobicContact CD2-CD1 3.85Å; L610-L635 HydrophobicContact CD1-CD1 4.23Å; L610-L635 HydrophobicContact CD1-CD2 3.83Å; L610-L635 HydrophobicContact CD2-CD2 3.98Å; T631-L635 WeakPolarHBondContact O-CB 3.49Å; T631-L635 PolarHBondContact O-N 2.98Å; L632-L635 HydrophobicContact CD2-CD2 4.48Å; L632-L635 WeakPolarHBondContact O-CB 3.4Å; L632-L635 PolarHBondContact O-N 3.48Å; I633-L635 VanDerWaalsContact C-N 3.3Å; I633-L635 PolarHBondContact O-N 3.26Å; L635-F638 HydrophobicContact CD1-CD1 4.45Å; L635-F638 PolarHBondContact O-N 2.85Å; L635-L639 HydrophobicContact CD1-CD1 4.33Å; L635-L639 HydrophobicContact CD1-CG 4.39Å; L635-L639 HydrophobicContact CG-CD1 4.18Å; L635-L639 WeakPolarHBondContact O-CB 3.37Å; L635-L639 WeakPolarHBondContact O-CG 3.19Å; L635-L639 PolarHBondContact O-N 3.01Å; L635-L662 HydrophobicContact CD1-CD2 4.09Å; L635-L665 HydrophobicContact CD2-CD1 3.81Å
636	F	83.7	Confident	79.6	Confident	2 Å²	2	22.9 Å²	22.9	1%	0.009	12%	0.118	C	C	.	.	H	α-helix	trans	-63.6	-43.4	175.8	-64.1	-48.1	0	0	0	111.6	L632 I633 F638 L639 T640 L665 Y669 L680 I709	L632-F636 HydrophobicContact CB-CE2 4.14Å; L632-F636 HydrophobicContact CD2-CZ 4.5Å; L632-F636 WeakPolarHBondContact O-CD2 3.33Å; L632-F636 WeakPolarHBondContact O-CG 3.44Å; L632-F636 PolarHBondContact O-N 3.44Å; I633-F636 PolarHBondContact O-N 3.18Å; F636-F638 PolarHBondContact O-N 2.94Å; F636-L639 PolarHBondContact O-N 3.24Å; F636-T640 WeakPolarHBondContact O-CB 3.27Å; F636-T640 PolarHBondContact O-N 3.33Å; F636-T640 PolarHBondContact O-OG1 3.03Å; F636-L665 HydrophobicContact CE1-CD2 3.99Å; F636-L665 HydrophobicContact CZ-CD2 4.29Å; F636-Y669 HydrophobicContact CB-CD2 4.07Å; F636-Y669 HydrophobicContact CB-CE1 4.44Å; F636-Y669 HydrophobicContact CB-CE2 3.97Å; F636-Y669 HydrophobicContact CB-CG 4.36Å; F636-Y669 AromaticContact CD1-CD2 3.84Å; F636-Y669 HydrophobicContact CD1-CD2 3.84Å; F636-Y669 AromaticContact CD1-CG 3.8Å; F636-Y669 HydrophobicContact CD1-CG 3.8Å; F636-Y669 HydrophobicContact CD2-CD2 4.13Å; F636-Y669 HydrophobicContact CD2-CE2 4.38Å; F636-Y669 HydrophobicContact CE1-CD2 4.34Å; F636-Y669 HydrophobicContact CE1-CG 4.35Å; F636-Y669 AromaticContact CG-CD2 3.75Å; F636-Y669 HydrophobicContact CG-CD2 3.75Å; F636-Y669 HydrophobicContact CG-CE2 4.08Å; F636-Y669 HydrophobicContact CG-CG 4.12Å; F636-L680 HydrophobicContact CB-CD2 4.29Å; F636-L680 HydrophobicContact CD2-CD2 4.49Å; F636-I709 HydrophobicContact CE1-CG2 4.47Å; F636-I709 HydrophobicContact CE2-CD1 3.96Å; F636-I709 HydrophobicContact CZ-CD1 3.81Å; F636-I709 HydrophobicContact CZ-CG2 3.86Å
637	K	83.4	Confident	79	Confident	10 Å²	10	23.4 Å²	23.4	4%	0.043	12%	0.119	C	C	.	.	H	α-helix	trans	-59	-47.8	174	-73.8	-175.7	172	-169.2	0	111.8	Y570 I633 L634 L639 T640 M641 L680 L683	Y570-K637 HydrophobicContact CD2-CB 3.72Å; Y570-K637 HydrophobicContact CE2-CB 3.62Å; Y570-K637 HydrophobicContact CE2-CD 4.28Å; Y570-K637 HydrophobicContact CE2-CG 4.49Å; I633-K637 HydrophobicContact CG2-CD 4.5Å; I633-K637 WeakPolarHBondContact O-CG 3.24Å; I633-K637 PolarHBondContact O-N 3.48Å; L634-K637 PolarHBondContact O-N 3.49Å; K637-L639 PolarHBondContact O-N 2.89Å; K637-T640 PolarHBondContact O-N 3.14Å; K637-M641 VanDerWaalsContact O-CG 3.29Å; K637-M641 WeakPolarHBondContact O-CG 3.47Å; K637-M641 PolarHBondContact O-N 3.45Å; K637-L680 WeakPolarHBondContact CE-O 3.46Å; K637-L683 PolarHBondContact NZ-O 2.95Å
638	F	86.9	Confident	78.5	Confident	0 Å²	0	22.8 Å²	22.8	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-57	-49.4	176.6	170.6	-99.8	0	0	0	112.5	M566 L569 M573 W599 L603 L606 L634 L635 F636 T640 M641 I642	M566-F638 HydrophobicContact CE-CB 4.13Å; M566-F638 HydrophobicContact CE-CD1 4.27Å; M566-F638 HydrophobicContact CE-CG 4.23Å; L569-F638 HydrophobicContact CB-CD2 4.08Å; L569-F638 HydrophobicContact CB-CE2 3.95Å; M573-F638 HydrophobicContact CB-CD2 4.24Å; M573-F638 HydrophobicContact CB-CE2 4.37Å; M573-F638 HydrophobicContact CG-CD2 3.58Å; M573-F638 HydrophobicContact CG-CE2 3.28Å; M573-F638 HydrophobicContact CG-CZ 4.34Å; M573-F638 HydrophobicContact SD-CE2 4.34Å; W599-F638 HydrophobicContact CE3-CE2 4.41Å; W599-F638 HydrophobicContact CE3-CZ 4.44Å; W599-F638 HydrophobicContact CH2-CE2 4.3Å; W599-F638 AromaticContact CZ3-CE2 3.67Å; W599-F638 HydrophobicContact CZ3-CE2 3.67Å; W599-F638 HydrophobicContact CZ3-CZ 4.08Å; L603-F638 HydrophobicContact CD2-CE1 3.86Å; L603-F638 HydrophobicContact CD2-CZ 4.04Å; L606-F638 HydrophobicContact CD2-CE1 4.14Å; L634-F638 VanDerWaalsContact O-CB 3.25Å; L634-F638 WeakPolarHBondContact O-CB 3.16Å; L634-F638 PolarHBondContact O-N 3.33Å; L635-F638 HydrophobicContact CD1-CD1 4.45Å; L635-F638 PolarHBondContact O-N 2.85Å; F636-F638 PolarHBondContact O-N 2.94Å; F638-T640 VanDerWaalsContact C-N 3.3Å; F638-T640 PolarHBondContact O-N 3.45Å; F638-M641 PolarHBondContact O-N 3.44Å; F638-I642 HydrophobicContact CD1-CD1 4.08Å; F638-I642 HydrophobicContact CE1-CD1 3.49Å; F638-I642 VanDerWaalsContact CE1-CD1 3.49Å; F638-I642 HydrophobicContact CE2-CD1 4.17Å; F638-I642 HydrophobicContact CZ-CD1 3.56Å; F638-I642 PolarHBondContact O-N 3.07Å; F638-I642 VanDerWaalsContact O-N 3.13Å
639	L	84.1	Confident	78.1	Confident	5 Å²	5	28.2 Å²	28.2	3%	0.026	14%	0.138	C	C	.	.	H	α-helix	trans	-63.6	-37.2	178.2	-70.4	172.2	0	0	0	112.2	L635 F636 K637 I642 N643 I655 L662 L665 Y666	L635-L639 HydrophobicContact CD1-CD1 4.33Å; L635-L639 HydrophobicContact CD1-CG 4.39Å; L635-L639 HydrophobicContact CG-CD1 4.18Å; L635-L639 WeakPolarHBondContact O-CB 3.37Å; L635-L639 WeakPolarHBondContact O-CG 3.19Å; L635-L639 PolarHBondContact O-N 3.01Å; F636-L639 PolarHBondContact O-N 3.24Å; K637-L639 PolarHBondContact O-N 2.89Å; L639-I642 PolarHBondContact O-N 3.35Å; L639-N643 PolarHBondContact O-N 3.26Å; L639-N643 VanDerWaalsContact O-N 3.09Å; L639-I655 HydrophobicContact CD2-CD1 4.22Å; L639-L662 HydrophobicContact CD2-CB 4.32Å; L639-L662 HydrophobicContact CD2-CD2 4.32Å; L639-L665 HydrophobicContact CD1-CB 4.3Å; L639-Y666 HydrophobicContact CB-CD2 4.15Å
640	T	80.3	Confident	78.2	Confident	8 Å²	8	30.8 Å²	30.8	5%	0.049	15%	0.152	C	C	.	.	H	α-helix	trans	-66.1	-42.1	177.2	-51.3	0	0	0	0	111.3	F636 K637 F638 I642 N643 M644 E681	F636-T640 WeakPolarHBondContact O-CB 3.27Å; F636-T640 PolarHBondContact O-N 3.33Å; F636-T640 PolarHBondContact O-OG1 3.03Å; K637-T640 PolarHBondContact O-N 3.14Å; F638-T640 VanDerWaalsContact C-N 3.3Å; F638-T640 PolarHBondContact O-N 3.45Å; T640-I642 VanDerWaalsContact C-N 3.31Å; T640-I642 PolarHBondContact O-N 2.9Å; T640-N643 PolarHBondContact O-N 3.34Å; T640-N643 VanDerWaalsContact O-N 3.1Å; T640-M644 HydrophobicContact CG2-CG 4.03Å; T640-M644 WeakPolarHBondContact O-CB 3.44Å; T640-M644 VanDerWaalsContact O-CG 3.28Å; T640-M644 WeakPolarHBondContact O-CG 3.22Å; T640-M644 PolarHBondContact O-N 3.17Å; T640-E681 HydrophobicContact CG2-CG 4.09Å; T640-E681 WeakPolarHBondContact CG2-OE1 3.3Å
641	M	79.3	Confident	78.3	Confident	27 Å²	27	30.3 Å²	30.3	13%	0.133	15%	0.15	C	C	.	.	H	α-helix	trans	-61.5	-37.4	175.1	-67.7	-57.5	-69.6	0	0	112.6	Y570 H574 Y577 K637 F638 N643 N645	Y570-M641 HydrophobicContact CD2-CG 4.36Å; Y570-M641 HydrophobicContact CE2-CG 3.94Å; H574-M641 HydrophobicContact CB-CE 4.33Å; Y577-M641 VanDerWaalsContact CB-CE 3.47Å; Y577-M641 HydrophobicContact CD1-CE 3.33Å; Y577-M641 HydrophobicContact CD2-CE 4.11Å; Y577-M641 HydrophobicContact CE1-CE 4.03Å; Y577-M641 HydrophobicContact CG-CE 3.36Å; K637-M641 VanDerWaalsContact O-CG 3.29Å; K637-M641 WeakPolarHBondContact O-CG 3.47Å; K637-M641 PolarHBondContact O-N 3.45Å; F638-M641 PolarHBondContact O-N 3.44Å; M641-N643 VanDerWaalsContact C-N 3.34Å; M641-N645 WeakPolarHBondContact O-CB 3.27Å; M641-N645 PolarHBondContact O-N 2.87Å
642	I	79.3	Confident	78.2	Confident	5 Å²	5	33.8 Å²	33.8	3%	0.026	16%	0.164	C	C	.	.	H	α-helix	trans	-63.3	-42.6	173.4	-67	171.7	0	0	0	110.6	M573 L603 F638 L639 T640 L651 I655	M573-I642 HydrophobicContact CE-CB 4.46Å; M573-I642 HydrophobicContact CE-CG1 3.51Å; M573-I642 HydrophobicContact SD-CG1 4.39Å; L603-I642 HydrophobicContact CD2-CD1 4.08Å; F638-I642 HydrophobicContact CD1-CD1 4.08Å; F638-I642 HydrophobicContact CE1-CD1 3.49Å; F638-I642 VanDerWaalsContact CE1-CD1 3.49Å; F638-I642 HydrophobicContact CE2-CD1 4.17Å; F638-I642 HydrophobicContact CZ-CD1 3.56Å; F638-I642 PolarHBondContact O-N 3.07Å; F638-I642 VanDerWaalsContact O-N 3.13Å; L639-I642 PolarHBondContact O-N 3.35Å; T640-I642 VanDerWaalsContact C-N 3.31Å; T640-I642 PolarHBondContact O-N 2.9Å; I642-L651 HydrophobicContact CG2-CB 4.14Å; I642-I655 HydrophobicContact CD1-CD1 3.96Å; I642-I655 HydrophobicContact CG2-CD1 4.02Å
643	N	73.4	Confident	78.2	Confident	42 Å²	42	38.2 Å²	38.2	23%	0.225	19%	0.185	C	C	.	.	H	α-helix	trans	-73.7	-34	-178.2	-178.1	70.8	0	0	0	113.8	L639 T640 M641 N645 K652 Y666	L639-N643 PolarHBondContact O-N 3.26Å; L639-N643 VanDerWaalsContact O-N 3.09Å; T640-N643 PolarHBondContact O-N 3.34Å; T640-N643 VanDerWaalsContact O-N 3.1Å; M641-N643 VanDerWaalsContact C-N 3.34Å; N643-N645 VanDerWaalsContact C-N 3.25Å; N643-N645 PolarHBondContact O-N 3.25Å; N643-K652 WeakPolarHBondContact OD1-CE 3.42Å; N643-K652 PolarHBondContact OD1-NZ 2.93Å; N643-Y666 HydrophobicContact CB-CE2 3.85Å; N643-Y666 PolarHBondContact ND2-OH 3.39Å; N643-Y666 PolarHBondContact OD1-OH 3.06Å
644	M	70.7	Confident	78.4	Confident	98 Å²	98	40.5 Å²	40.5	48%	0.483	19%	0.194	S	C	.	.	H	α-helix	trans	-76.2	-10.8	179.6	-68.6	-69.8	-85.7	0	0	113.2	Y577 T640	Y577-M644 HydrophobicContact CE2-CB 4.36Å; T640-M644 HydrophobicContact CG2-CG 4.03Å; T640-M644 WeakPolarHBondContact O-CB 3.44Å; T640-M644 VanDerWaalsContact O-CG 3.28Å; T640-M644 WeakPolarHBondContact O-CG 3.22Å; T640-M644 PolarHBondContact O-N 3.17Å
645	N	67.7	Low	78.4	Confident	4 Å²	4	41 Å²	41	2%	0.021	20%	0.197	C	C	.	.			trans	-97.1	100	-178.3	-160.8	-22.1	0	0	0	112.1	Y577 M641 N643 H647 I648	Y577-N645 HydrophobicContact CD2-CB 3.72Å; Y577-N645 HydrophobicContact CE2-CB 4.14Å; M641-N645 WeakPolarHBondContact O-CB 3.27Å; M641-N645 PolarHBondContact O-N 2.87Å; N643-N645 VanDerWaalsContact C-N 3.25Å; N643-N645 PolarHBondContact O-N 3.25Å; N645-H647 PolarHBondContact O-N 3.33Å; N645-H647 WeakPolarHBondContact OD1-CB 3.41Å; N645-H647 PolarHBondContact OD1-N 3.39Å; N645-I648 HydrophobicContact CB-CB 4.22Å; N645-I648 HydrophobicContact CB-CD1 3.69Å; N645-I648 HydrophobicContact CB-CG1 3.88Å; N645-I648 VanDerWaalsContact CG-CG1 3.49Å; N645-I648 WeakPolarHBondContact ND2-CD1 3.31Å; N645-I648 WeakPolarHBondContact ND2-CG1 3.17Å; N645-I648 PolarHBondContact O-N 3.09Å
646	D	62.7	Low	78.3	Confident	149 Å²	149	45.4 Å²	45.4	80%	0.797	22%	0.217	S	C	*	.	G	3₁₀ helix	trans	-59.3	-27.3	176.3	-73.2	-28.4	0	0	0	113	I648	D646-I648 PolarHBondContact O-N 2.91Å
647	H	64.4	Low	78.5	Confident	88 Å²	88	49.3 Å²	49.3	41%	0.407	25%	0.245	S	C	.	.	G	3₁₀ helix	trans	-71.4	-14.6	177.6	-62.4	-80.3	0	0	0	113.3	Y596 N645	Y596-H647 PolarHBondContact OH-O 3.49Å; Y596-H647 VanDerWaalsContact OH-O 3.06Å; N645-H647 PolarHBondContact O-N 3.33Å; N645-H647 WeakPolarHBondContact OD1-CB 3.41Å; N645-H647 PolarHBondContact OD1-N 3.39Å
648	I	71.1	Confident	78.7	Confident	0 Å²	0	52.9 Å²	52.9	0%	0	27%	0.265	C	S	.	.	G	3₁₀ helix	trans	-114.3	35	-175.2	-46.7	173.3	0	0	0	111.2	M573 M576 Y596 N645 D646 L650 L651 K652	M573-I648 HydrophobicContact CE-CD1 3.47Å; M573-I648 VanDerWaalsContact CE-CD1 3.47Å; M576-I648 HydrophobicContact CE-CD1 3.16Å; M576-I648 HydrophobicContact CE-CG1 4Å; Y596-I648 HydrophobicContact CD1-CG2 4.29Å; Y596-I648 HydrophobicContact CE1-CB 4.37Å; Y596-I648 HydrophobicContact CE1-CG1 4.1Å; Y596-I648 HydrophobicContact CE1-CG2 3.77Å; N645-I648 HydrophobicContact CB-CB 4.22Å; N645-I648 HydrophobicContact CB-CD1 3.69Å; N645-I648 HydrophobicContact CB-CG1 3.88Å; N645-I648 VanDerWaalsContact CG-CG1 3.49Å; N645-I648 WeakPolarHBondContact ND2-CD1 3.31Å; N645-I648 WeakPolarHBondContact ND2-CG1 3.17Å; N645-I648 PolarHBondContact O-N 3.09Å; D646-I648 PolarHBondContact O-N 2.91Å; I648-L650 PolarHBondContact O-N 3.44Å; I648-L650 VanDerWaalsContact O-N 3.09Å; I648-L651 HydrophobicContact CG2-CB 3.47Å; I648-L651 VanDerWaalsContact CG2-CB 3.47Å; I648-L651 HydrophobicContact CG2-CD1 3.32Å; I648-L651 HydrophobicContact CG2-CG 3.31Å; I648-L651 PolarHBondContact O-N 3Å; I648-L651 VanDerWaalsContact O-N 3.13Å; I648-K652 PolarHBondContact O-N 2.7Å
649	K	74.4	Confident	78.7	Confident	132 Å²	132	53 Å²	53	57%	0.574	27%	0.265	S	S	*	.	H	α-helix	trans	-53.5	-33.5	176.4	-162.9	-174.3	-178.5	-135.2	0	112.9	K652 E653	K649-K652 WeakPolarHBondContact O-CB 3.5Å; K649-K652 PolarHBondContact O-N 3.07Å; K649-E653 WeakPolarHBondContact CE-OE1 3.42Å; K649-E653 HydrophobicContact CG-CG 4.45Å; K649-E653 IonicContact NZ-OE1 2.77Å; K649-E653 PolarHBondContact NZ-OE1 3.19Å; K649-E653 WeakPolarHBondContact O-CG 3.21Å; K649-E653 PolarHBondContact O-N 3.34Å
650	L	79.3	Confident	78.7	Confident	60 Å²	60	56.9 Å²	56.9	31%	0.314	29%	0.291	S	S	.	.	H	α-helix	trans	-62.7	-41.8	179.4	-168.8	152.6	0	0	0	112.9	I600 I648 Y654	I600-L650 HydrophobicContact CD1-CD2 3.94Å; I600-L650 HydrophobicContact CG1-CD2 4.45Å; I648-L650 PolarHBondContact O-N 3.44Å; I648-L650 VanDerWaalsContact O-N 3.09Å; L650-Y654 VanDerWaalsContact O-CB 3.31Å; L650-Y654 WeakPolarHBondContact O-CB 3.49Å; L650-Y654 PolarHBondContact O-N 3.14Å
651	L	83.3	Confident	78.8	Confident	0 Å²	0	58.1 Å²	58.1	0%	0	30%	0.297	C	S	.	.	H	α-helix	trans	-70.3	-35.5	177.7	-64	-174	0	0	0	111.3	Y596 W599 I600 L603 I642 I648 Y654 I655	Y596-L651 HydrophobicContact CD1-CD1 4.07Å; Y596-L651 HydrophobicContact CD1-CD2 4.27Å; Y596-L651 HydrophobicContact CD1-CG 3.99Å; W599-L651 HydrophobicContact CB-CD1 3.57Å; W599-L651 HydrophobicContact CB-CD2 3.69Å; W599-L651 HydrophobicContact CB-CG 4.3Å; W599-L651 HydrophobicContact CD2-CD1 4.44Å; W599-L651 HydrophobicContact CG-CD1 3.83Å; I600-L651 HydrophobicContact CG1-CD2 3.96Å; L603-L651 HydrophobicContact CD1-CB 4.15Å; L603-L651 HydrophobicContact CD1-CD1 4.47Å; L603-L651 HydrophobicContact CD1-CD2 3.95Å; L603-L651 HydrophobicContact CD1-CG 4.42Å; I642-L651 HydrophobicContact CG2-CB 4.14Å; I648-L651 HydrophobicContact CG2-CB 3.47Å; I648-L651 VanDerWaalsContact CG2-CB 3.47Å; I648-L651 HydrophobicContact CG2-CD1 3.32Å; I648-L651 HydrophobicContact CG2-CG 3.31Å; I648-L651 PolarHBondContact O-N 3Å; I648-L651 VanDerWaalsContact O-N 3.13Å; L651-Y654 PolarHBondContact O-N 3.07Å; L651-I655 WeakPolarHBondContact O-CG1 3.33Å; L651-I655 PolarHBondContact O-N 2.7Å
652	K	81.8	Confident	79.1	Confident	75 Å²	75	56.9 Å²	56.9	33%	0.326	29%	0.29	S	S	.	.	H	α-helix	trans	-61.3	-52.9	173.6	178	175.6	175.5	167.8	0	111.3	N643 I648 K649 Y654 I655 E656	N643-K652 WeakPolarHBondContact OD1-CE 3.42Å; N643-K652 PolarHBondContact OD1-NZ 2.93Å; I648-K652 PolarHBondContact O-N 2.7Å; K649-K652 WeakPolarHBondContact O-CB 3.5Å; K649-K652 PolarHBondContact O-N 3.07Å; K652-Y654 PolarHBondContact O-N 3.13Å; K652-I655 PolarHBondContact O-N 3.38Å; K652-I655 VanDerWaalsContact O-N 3.11Å; K652-E656 WeakPolarHBondContact CE-OE1 3.27Å; K652-E656 WeakPolarHBondContact O-CG 3.2Å; K652-E656 PolarHBondContact O-N 2.87Å
653	E	84.1	Confident	79.3	Confident	94 Å²	94	61 Å²	61	44%	0.439	31%	0.306	S	S	.	.	H	α-helix	trans	-57.3	-39.1	176.4	-72.1	176.1	-176.5	0	0	110.9	K649 E656 S657	K649-E653 WeakPolarHBondContact CE-OE1 3.42Å; K649-E653 HydrophobicContact CG-CG 4.45Å; K649-E653 IonicContact NZ-OE1 2.77Å; K649-E653 PolarHBondContact NZ-OE1 3.19Å; K649-E653 WeakPolarHBondContact O-CG 3.21Å; K649-E653 PolarHBondContact O-N 3.34Å; E653-E656 PolarHBondContact O-N 3.22Å; E653-S657 PolarHBondContact O-N 3.36Å; E653-S657 PolarHBondContact O-OG 3.42Å; E653-S657 VanDerWaalsContact O-OG 3.06Å
654	Y	85.4	Confident	79.6	Confident	48 Å²	48	63.4 Å²	63.4	19%	0.188	32%	0.315	C	S	.	.	H	α-helix	trans	-64	-41.9	175.8	-173.8	-92.3	0	0	0	113.3	I600 L603 T604 L650 L651 K652 S657 N658	I600-Y654 HydrophobicContact CG1-CD2 4.45Å; I600-Y654 HydrophobicContact CG1-CG 4.5Å; I600-Y654 HydrophobicContact CG2-CD2 4.21Å; I600-Y654 HydrophobicContact CG2-CE1 4.07Å; I600-Y654 HydrophobicContact CG2-CE2 3.65Å; L603-Y654 HydrophobicContact CB-CD1 4.39Å; L603-Y654 HydrophobicContact CB-CE1 4.32Å; L603-Y654 HydrophobicContact CD1-CD1 4.32Å; T604-Y654 PolarHBondContact OG1-OH 2.88Å; L650-Y654 VanDerWaalsContact O-CB 3.31Å; L650-Y654 WeakPolarHBondContact O-CB 3.49Å; L650-Y654 PolarHBondContact O-N 3.14Å; L651-Y654 PolarHBondContact O-N 3.07Å; K652-Y654 PolarHBondContact O-N 3.13Å; Y654-S657 PolarHBondContact O-N 3.12Å; Y654-S657 PolarHBondContact O-OG 3.22Å; Y654-N658 HydrophobicContact CD1-CB 4.42Å; Y654-N658 HydrophobicContact CD2-CB 4.4Å; Y654-N658 WeakPolarHBondContact CD2-ND2 3.06Å; Y654-N658 HydrophobicContact CE1-CB 4Å; Y654-N658 HydrophobicContact CE2-CB 3.98Å; Y654-N658 WeakPolarHBondContact CE2-ND2 3.43Å; Y654-N658 WeakPolarHBondContact O-CB 3.48Å; Y654-N658 PolarHBondContact O-N 3.37Å
655	I	84.6	Confident	80.1	Confident	12 Å²	12	58.7 Å²	58.7	6%	0.062	29%	0.292	C	S	.	.	H	α-helix	trans	-62.4	-46.2	176.5	-71.5	168.2	0	0	0	110.2	L603 L639 I642 L651 K652 S657 C659 L662	L603-I655 HydrophobicContact CD1-CD1 4.18Å; L603-I655 HydrophobicContact CD1-CG1 3.97Å; L603-I655 HydrophobicContact CD2-CD1 4Å; L603-I655 HydrophobicContact CD2-CG1 4.18Å; L639-I655 HydrophobicContact CD2-CD1 4.22Å; I642-I655 HydrophobicContact CD1-CD1 3.96Å; I642-I655 HydrophobicContact CG2-CD1 4.02Å; L651-I655 WeakPolarHBondContact O-CG1 3.33Å; L651-I655 PolarHBondContact O-N 2.7Å; K652-I655 PolarHBondContact O-N 3.38Å; K652-I655 VanDerWaalsContact O-N 3.11Å; I655-S657 VanDerWaalsContact C-N 3.31Å; I655-S657 PolarHBondContact O-N 2.84Å; I655-C659 HydrophobicContact CB-CB 4.49Å; I655-C659 HydrophobicContact CG2-CB 4.33Å; I655-C659 CarbonylContact O-C 3.53Å; I655-C659 PolarHBondContact O-N 2.88Å; I655-L662 HydrophobicContact CG2-CB 4.07Å
656	E	85.3	Confident	80.5	Confident	95 Å²	95	60.6 Å²	60.6	44%	0.444	30%	0.299	S	S	.	.	H	α-helix	trans	-60	-39.9	179.2	-68.8	178.1	-174.6	0	0	112	K652 E653 Y663	K652-E656 WeakPolarHBondContact CE-OE1 3.27Å; K652-E656 WeakPolarHBondContact O-CG 3.2Å; K652-E656 PolarHBondContact O-N 2.87Å; E653-E656 PolarHBondContact O-N 3.22Å; E656-Y663 HydrophobicContact CB-CD2 4.39Å; E656-Y663 HydrophobicContact CB-CE2 4.37Å; E656-Y663 HydrophobicContact CG-CD2 3.82Å; E656-Y663 HydrophobicContact CG-CE2 3.63Å
657	S	86.7	Confident	81.1	Confident	84 Å²	84	56.4 Å²	56.4	59%	0.587	28%	0.277	S	S	*	.	H	α-helix	trans	-87.4	-34	-176.8	62.8	0	0	0	0	114.9	E653 Y654 I655	E653-S657 PolarHBondContact O-N 3.36Å; E653-S657 PolarHBondContact O-OG 3.42Å; E653-S657 VanDerWaalsContact O-OG 3.06Å; Y654-S657 PolarHBondContact O-N 3.12Å; Y654-S657 PolarHBondContact O-OG 3.22Å; I655-S657 VanDerWaalsContact C-N 3.31Å; I655-S657 PolarHBondContact O-N 2.84Å
658	N	87.6	Confident	81.2	Confident	85 Å²	85	53 Å²	53	46%	0.455	26%	0.262	S	S	.	.	H	α-helix	trans	-123.4	-16.8	-166.2	-59.7	-60.5	0	0	0	115	Y654 P660	Y654-N658 HydrophobicContact CD1-CB 4.42Å; Y654-N658 HydrophobicContact CD2-CB 4.4Å; Y654-N658 WeakPolarHBondContact CD2-ND2 3.06Å; Y654-N658 HydrophobicContact CE1-CB 4Å; Y654-N658 HydrophobicContact CE2-CB 3.98Å; Y654-N658 WeakPolarHBondContact CE2-ND2 3.43Å; Y654-N658 WeakPolarHBondContact O-CB 3.48Å; Y654-N658 PolarHBondContact O-N 3.37Å; N658-P660 VanDerWaalsContact C-CD 3.48Å; N658-P660 WeakPolarHBondContact O-CD 3.44Å
659	C	86.9	Confident	80.9	Confident	1 Å²	1	54.4 Å²	54.4	1%	0.007	27%	0.267	C	S	.	.			trans	-116.9	72.8	-175.5	-58.4	0	0	0	0	111.4	N607 I655 I661 L662 Y663	N607-C659 HydrophobicContact CB-CB 4.02Å; N607-C659 WeakPolarHBondContact OD1-CA 3.12Å; I655-C659 HydrophobicContact CB-CB 4.49Å; I655-C659 HydrophobicContact CG2-CB 4.33Å; I655-C659 CarbonylContact O-C 3.53Å; I655-C659 PolarHBondContact O-N 2.88Å; C659-I661 PolarHBondContact O-N 2.89Å; C659-I661 VanDerWaalsContact O-N 3.15Å; C659-L662 HydrophobicContact CB-CB 3.96Å; C659-L662 HydrophobicContact CB-CD1 3.94Å; C659-L662 HydrophobicContact CB-CG 4.24Å; C659-L662 PolarHBondContact O-N 3.31Å; C659-Y663 WeakPolarHBondContact O-CB 3.03Å; C659-Y663 PolarHBondContact O-N 2.99Å
660	P	84.2	Confident	80.4	Confident	87 Å²	87	50.2 Å²	50.2	57%	0.565	25%	0.254	S	S	*	.	H	α-helix	trans	-61.1	-29.8	-172	24.7	-35.4	0	0	0	113.8	N658 K664	N658-P660 VanDerWaalsContact C-CD 3.48Å; N658-P660 WeakPolarHBondContact O-CD 3.44Å; P660-K664 VanDerWaalsContact O-CB 3.3Å; P660-K664 WeakPolarHBondContact O-CB 3.28Å; P660-K664 PolarHBondContact O-N 3.13Å
661	I	83.7	Confident	79.5	Confident	35 Å²	35	51.6 Å²	51.6	18%	0.179	27%	0.269	C	S	.	.	H	α-helix	trans	-75.4	-46.6	-179.7	-64.5	162.7	0	0	0	110	N607 L610 K611 L614 C659 Y663 K664 L665	N607-I661 VanDerWaalsContact O-CD1 3.31Å; N607-I661 WeakPolarHBondContact O-CD1 3.29Å; N607-I661 WeakPolarHBondContact OD1-CB 3.29Å; N607-I661 PolarHBondContact OD1-N 3.45Å; L610-I661 HydrophobicContact CB-CG2 4.27Å; K611-I661 HydrophobicContact CB-CD1 3.45Å; K611-I661 VanDerWaalsContact CB-CD1 3.45Å; K611-I661 HydrophobicContact CD-CD1 4.08Å; K611-I661 HydrophobicContact CG-CD1 3.77Å; L614-I661 HydrophobicContact CD1-CG2 3.62Å; C659-I661 PolarHBondContact O-N 2.89Å; C659-I661 VanDerWaalsContact O-N 3.15Å; I661-Y663 VanDerWaalsContact C-N 3.33Å; I661-K664 PolarHBondContact O-N 2.81Å; I661-L665 HydrophobicContact CG2-CD1 4.04Å; I661-L665 WeakPolarHBondContact O-CB 3.06Å; I661-L665 WeakPolarHBondContact O-CG 3.44Å; I661-L665 PolarHBondContact O-N 2.96Å
662	L	85.3	Confident	78	Confident	0 Å²	0	53.2 Å²	53.2	0%	0	28%	0.276	C	S	.	.	H	α-helix	trans	-62.2	-42.5	175.6	-67.3	178.5	0	0	0	111.4	L603 L606 N607 L610 L635 L639 I655 C659 L665 Y666	L603-L662 HydrophobicContact CD2-CD1 3.88Å; L606-L662 HydrophobicContact CD2-CD1 4.24Å; L606-L662 HydrophobicContact CD2-CD2 3.93Å; L606-L662 HydrophobicContact CG-CD2 4.23Å; N607-L662 HydrophobicContact CB-CD1 4.19Å; N607-L662 HydrophobicContact CB-CG 4.22Å; L610-L662 HydrophobicContact CD1-CD2 3.38Å; L610-L662 HydrophobicContact CD1-CG 4.42Å; L635-L662 HydrophobicContact CD1-CD2 4.09Å; L639-L662 HydrophobicContact CD2-CB 4.32Å; L639-L662 HydrophobicContact CD2-CD2 4.32Å; I655-L662 HydrophobicContact CG2-CB 4.07Å; C659-L662 HydrophobicContact CB-CB 3.96Å; C659-L662 HydrophobicContact CB-CD1 3.94Å; C659-L662 HydrophobicContact CB-CG 4.24Å; C659-L662 PolarHBondContact O-N 3.31Å; L662-L665 HydrophobicContact CD2-CD1 4.44Å; L662-L665 WeakPolarHBondContact O-CB 3.3Å; L662-L665 PolarHBondContact O-N 3.46Å; L662-Y666 WeakPolarHBondContact O-CB 3.42Å; L662-Y666 PolarHBondContact O-N 3.42Å
663	Y	82.6	Confident	76.3	Confident	91 Å²	91	55.1 Å²	55.1	36%	0.357	30%	0.295	S	S	.	.	H	α-helix	trans	-62.9	-43.7	176.2	-176.9	-117.7	0	0	0	112.1	E656 C659 I661 Y666 N667	E656-Y663 HydrophobicContact CB-CD2 4.39Å; E656-Y663 HydrophobicContact CB-CE2 4.37Å; E656-Y663 HydrophobicContact CG-CD2 3.82Å; E656-Y663 HydrophobicContact CG-CE2 3.63Å; C659-Y663 WeakPolarHBondContact O-CB 3.03Å; C659-Y663 PolarHBondContact O-N 2.99Å; I661-Y663 VanDerWaalsContact C-N 3.33Å; Y663-Y666 PolarHBondContact O-N 3.14Å; Y663-N667 WeakPolarHBondContact CE1-ND2 3.47Å; Y663-N667 WeakPolarHBondContact CE2-ND2 3.22Å; Y663-N667 WeakPolarHBondContact O-CB 3.38Å; Y663-N667 PolarHBondContact O-N 3.45Å; Y663-N667 PolarHBondContact O-ND2 3.3Å; Y663-N667 PolarHBondContact OH-ND2 2.9Å
664	K	80.6	Confident	74.1	Confident	93 Å²	93	58.2 Å²	58.2	40%	0.404	31%	0.313	S	S	.	.	H	α-helix	trans	-62.1	-48.1	174.6	-172.5	179.3	179.3	-173.9	0	111.5	P660 I661 Y666 N667 V668 D712 I713	P660-K664 VanDerWaalsContact O-CB 3.3Å; P660-K664 WeakPolarHBondContact O-CB 3.28Å; P660-K664 PolarHBondContact O-N 3.13Å; I661-K664 PolarHBondContact O-N 2.81Å; K664-Y666 VanDerWaalsContact C-N 3.32Å; K664-Y666 PolarHBondContact O-N 2.93Å; K664-N667 PolarHBondContact O-N 2.93Å; K664-V668 HydrophobicContact CG-CG2 4.32Å; K664-V668 VanDerWaalsContact O-CG2 3.29Å; K664-V668 WeakPolarHBondContact O-CG2 3.42Å; K664-V668 PolarHBondContact O-N 3.49Å; K664-D712 PolarHBondContact NZ-O 3.22Å; K664-I713 PolarHBondContact NZ-O 3Å
665	L	80	Confident	71.9	Confident	0 Å²	0	59.1 Å²	59.1	0%	0	32%	0.321	C	S	.	.	H	α-helix	trans	-53.9	-48.2	176.7	-88.1	161.7	0	0	0	111.9	L610 L614 L635 F636 L639 I661 L662 V668 Y669 I713	L610-L665 HydrophobicContact CD1-CD1 4.14Å; L614-L665 HydrophobicContact CD1-CD1 4.14Å; L635-L665 HydrophobicContact CD2-CD1 3.81Å; F636-L665 HydrophobicContact CE1-CD2 3.99Å; F636-L665 HydrophobicContact CZ-CD2 4.29Å; L639-L665 HydrophobicContact CD1-CB 4.3Å; I661-L665 HydrophobicContact CG2-CD1 4.04Å; I661-L665 WeakPolarHBondContact O-CB 3.06Å; I661-L665 WeakPolarHBondContact O-CG 3.44Å; I661-L665 PolarHBondContact O-N 2.96Å; L662-L665 HydrophobicContact CD2-CD1 4.44Å; L662-L665 WeakPolarHBondContact O-CB 3.3Å; L662-L665 PolarHBondContact O-N 3.46Å; L665-V668 PolarHBondContact O-N 3.18Å; L665-Y669 WeakPolarHBondContact O-CB 3.34Å; L665-Y669 PolarHBondContact O-N 3.37Å; L665-I713 HydrophobicContact CD2-CD1 3.3Å; L665-I713 HydrophobicContact CG-CD1 3.94Å
666	Y	76.4	Confident	69.8	Low	44 Å²	44	64.3 Å²	64.3	17%	0.173	36%	0.358	C	S	.	.	H	α-helix	trans	-62.3	-47.7	177.7	177.3	-100	0	0	0	112.1	L639 N643 L662 Y663 K664 V668 Y669 C670	L639-Y666 HydrophobicContact CB-CD2 4.15Å; N643-Y666 HydrophobicContact CB-CE2 3.85Å; N643-Y666 PolarHBondContact ND2-OH 3.39Å; N643-Y666 PolarHBondContact OD1-OH 3.06Å; L662-Y666 WeakPolarHBondContact O-CB 3.42Å; L662-Y666 PolarHBondContact O-N 3.42Å; Y663-Y666 PolarHBondContact O-N 3.14Å; K664-Y666 VanDerWaalsContact C-N 3.32Å; K664-Y666 PolarHBondContact O-N 2.93Å; Y666-V668 VanDerWaalsContact C-N 3.32Å; Y666-V668 PolarHBondContact O-N 3.32Å; Y666-Y669 PolarHBondContact O-N 3.43Å; Y666-C670 WeakPolarHBondContact CE2-SG 3.47Å; Y666-C670 PolarHBondContact O-N 3.25Å; Y666-C670 PolarHBondContact O-SG 3.49Å; Y666-C670 PolarHBondContact OH-SG 2.9Å; Y666-C670 VanDerWaalsContact OH-SG 3.35Å
667	N	75	Confident	68	Low	61 Å²	61	64.7 Å²	64.7	33%	0.326	37%	0.371	S	S	.	.	H	α-helix	trans	-63.5	-37.2	178.6	-75.1	-24.4	0	0	0	112.7	Y663 K664 S671	Y663-N667 WeakPolarHBondContact CE1-ND2 3.47Å; Y663-N667 WeakPolarHBondContact CE2-ND2 3.22Å; Y663-N667 WeakPolarHBondContact O-CB 3.38Å; Y663-N667 PolarHBondContact O-N 3.45Å; Y663-N667 PolarHBondContact O-ND2 3.3Å; Y663-N667 PolarHBondContact OH-ND2 2.9Å; K664-N667 PolarHBondContact O-N 2.93Å; N667-S671 WeakPolarHBondContact O-CB 3.35Å; N667-S671 PolarHBondContact O-N 3.25Å; N667-S671 PolarHBondContact O-OG 3.44Å
668	V	66.4	Low	66.3	Low	16 Å²	16	64 Å²	64	10%	0.097	36%	0.361	C	S	.	.	H	α-helix	trans	-65.8	-45.3	175.7	174.8	0	0	0	0	109.5	K664 L665 Y666 C670 S671 Q672 I709 D712	K664-V668 HydrophobicContact CG-CG2 4.32Å; K664-V668 VanDerWaalsContact O-CG2 3.29Å; K664-V668 WeakPolarHBondContact O-CG2 3.42Å; K664-V668 PolarHBondContact O-N 3.49Å; L665-V668 PolarHBondContact O-N 3.18Å; Y666-V668 VanDerWaalsContact C-N 3.32Å; Y666-V668 PolarHBondContact O-N 3.32Å; V668-C670 PolarHBondContact O-N 3.3Å; V668-S671 WeakPolarHBondContact CA-OG 3.29Å; V668-S671 PolarHBondContact O-N 2.89Å; V668-S671 PolarHBondContact O-OG 2.94Å; V668-S671 VanDerWaalsContact O-OG 3.06Å; V668-Q672 HydrophobicContact CG1-CG 4.5Å; V668-Q672 WeakPolarHBondContact O-CB 3.47Å; V668-Q672 WeakPolarHBondContact O-CG 3.41Å; V668-Q672 PolarHBondContact O-N 2.78Å; V668-I709 HydrophobicContact CG1-CB 4.23Å; V668-I709 HydrophobicContact CG1-CG1 4.09Å; V668-I709 HydrophobicContact CG1-CG2 3.78Å; V668-D712 HydrophobicContact CG1-CB 4.17Å
669	Y	66.2	Low	64.8	Low	30 Å²	30	63 Å²	63	12%	0.118	36%	0.36	C	S	.	.	H	α-helix	trans	-60.2	-47	176.8	177.3	-107.2	0	0	0	112.4	F636 L665 Y666 Q672 L680 Y705	F636-Y669 HydrophobicContact CB-CD2 4.07Å; F636-Y669 HydrophobicContact CB-CE1 4.44Å; F636-Y669 HydrophobicContact CB-CE2 3.97Å; F636-Y669 HydrophobicContact CB-CG 4.36Å; F636-Y669 AromaticContact CD1-CD2 3.84Å; F636-Y669 HydrophobicContact CD1-CD2 3.84Å; F636-Y669 AromaticContact CD1-CG 3.8Å; F636-Y669 HydrophobicContact CD1-CG 3.8Å; F636-Y669 HydrophobicContact CD2-CD2 4.13Å; F636-Y669 HydrophobicContact CD2-CE2 4.38Å; F636-Y669 HydrophobicContact CE1-CD2 4.34Å; F636-Y669 HydrophobicContact CE1-CG 4.35Å; F636-Y669 AromaticContact CG-CD2 3.75Å; F636-Y669 HydrophobicContact CG-CD2 3.75Å; F636-Y669 HydrophobicContact CG-CE2 4.08Å; F636-Y669 HydrophobicContact CG-CG 4.12Å; L665-Y669 WeakPolarHBondContact O-CB 3.34Å; L665-Y669 PolarHBondContact O-N 3.37Å; Y666-Y669 PolarHBondContact O-N 3.43Å; Y669-Q672 CarbonylContact O-C 3.6Å; Y669-L680 HydrophobicContact CE2-CD2 4.27Å; Y669-Y705 HydrophobicContact CD2-CE1 4.43Å
670	C	63.4	Low	63.4	Low	44 Å²	44	63.7 Å²	63.7	30%	0.297	36%	0.364	S	S	.	.	H	α-helix	trans	-72.1	-33.4	178.7	-68.3	0	0	0	0	114	Y666 V668 T673	Y666-C670 WeakPolarHBondContact CE2-SG 3.47Å; Y666-C670 PolarHBondContact O-N 3.25Å; Y666-C670 PolarHBondContact O-SG 3.49Å; Y666-C670 PolarHBondContact OH-SG 2.9Å; Y666-C670 VanDerWaalsContact OH-SG 3.35Å; V668-C670 PolarHBondContact O-N 3.3Å; C670-T673 VanDerWaalsContact O-CG2 3.26Å; C670-T673 WeakPolarHBondContact O-CG2 3.5Å; C670-T673 PolarHBondContact O-OG1 2.99Å
671	S	59.5	Low	62.1	Low	89 Å²	89	64.3 Å²	64.3	62%	0.622	36%	0.359	S	S	*	.	H	α-helix	trans	-73.3	-30.1	177	59.2	0	0	0	0	112.2	N667 V668 T673	N667-S671 WeakPolarHBondContact O-CB 3.35Å; N667-S671 PolarHBondContact O-N 3.25Å; N667-S671 PolarHBondContact O-OG 3.44Å; V668-S671 WeakPolarHBondContact CA-OG 3.29Å; V668-S671 PolarHBondContact O-N 2.89Å; V668-S671 PolarHBondContact O-OG 2.94Å; V668-S671 VanDerWaalsContact O-OG 3.06Å; S671-T673 PolarHBondContact O-N 2.97Å
672	Q	52.6	Low	61	Low	34 Å²	34	66.3 Å²	66.3	16%	0.159	38%	0.376	C	S	.	.	T	Hydrogen-bonded Turn	trans	-87.1	51.5	170.6	-60.6	-173.3	-0.8	0	0	112.1	V668 Y669 L674 Y705 D712	V668-Q672 HydrophobicContact CG1-CG 4.5Å; V668-Q672 WeakPolarHBondContact O-CB 3.47Å; V668-Q672 WeakPolarHBondContact O-CG 3.41Å; V668-Q672 PolarHBondContact O-N 2.78Å; Y669-Q672 CarbonylContact O-C 3.6Å; Q672-L674 PolarHBondContact O-N 2.84Å; Q672-Y705 HydrophobicContact CB-CE2 3.77Å; Q672-Y705 PolarHBondContact O-OH 3.23Å; Q672-Y705 VanDerWaalsContact O-OH 3.09Å; Q672-Y705 VanDerWaalsContact OE1-CE2 3.23Å; Q672-D712 PolarHBondContact NE2-OD2 3.11Å
673	T	45.4	Very low	59.6	Low	115 Å²	115	67.1 Å²	67.1	71%	0.706	38%	0.38	S	S	*	.			trans	-68.2	28.5	174.4	15.8	0	0	0	0	113.9	C670 S671	C670-T673 VanDerWaalsContact O-CG2 3.26Å; C670-T673 WeakPolarHBondContact O-CG2 3.5Å; C670-T673 PolarHBondContact O-OG1 2.99Å; S671-T673 PolarHBondContact O-N 2.97Å
674	L	37.4	Very low	58.7	Low	158 Å²	158	66 Å²	66	83%	0.827	38%	0.383	S	S	*	.			trans	-100.4	22.8	-170.8	-106	149.3	0	0	0	114.8	Q672	Q672-L674 PolarHBondContact O-N 2.84Å
675	L	39.9	Very low	57.8	Low	67 Å²	67	63.4 Å²	63.4	35%	0.351	37%	0.373	S	S	.	.			trans	-110.3	67	158.1	-107.1	150.6	0	0	0	109.4	S677 I678	L675-S677 PolarHBondContact O-N 2.77Å; L675-I678 HydrophobicContact CD2-CB 4.35Å
676	S	41.5	Very low	56.8	Low	122 Å²	122	67.1 Å²	67.1	85%	0.853	39%	0.389	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.6	18.6	173.8	55.3	0	0	0	0	114.7
677	S	46.8	Very low	56	Low	102 Å²	102	68.9 Å²	68.9	71%	0.713	40%	0.399	S	S	*	.	T	Hydrogen-bonded Turn	trans	-126.5	-17.9	173.5	55.2	0	0	0	0	115	L675	L675-S677 PolarHBondContact O-N 2.77Å
678	I	50	Low	55.3	Low	71 Å²	71	66 Å²	66	36%	0.364	38%	0.383	S	S	.	.			trans	-139.6	103.3	179.3	-52.8	175.1	0	0	0	107.9	L675 L680 L683	L675-I678 HydrophobicContact CD2-CB 4.35Å; I678-L680 PolarHBondContact O-N 3.41Å; I678-L683 HydrophobicContact CG2-CD1 3.56Å; I678-L683 HydrophobicContact CG2-CD2 3.64Å; I678-L683 HydrophobicContact CG2-CG 3.54Å
679	S	57.3	Low	54.8	Low	64 Å²	64	68.8 Å²	68.8	45%	0.448	40%	0.395	S	S	.	.			trans	-63.2	116.6	167.5	40	0	0	0	0	108.5	E681 S682 L683	S679-E681 PolarHBondContact O-N 3.4Å; S679-S682 PolarHBondContact O-N 3.25Å; S679-S682 PolarHBondContact O-OG 2.94Å; S679-S682 WeakPolarHBondContact OG-CB 3.46Å; S679-S682 PolarHBondContact OG-OG 3.17Å; S679-L683 PolarHBondContact O-N 2.85Å
680	L	56.3	Low	54.4	Low	15 Å²	15	72.7 Å²	72.7	8%	0.079	42%	0.415	C	S	.	.	T	Hydrogen-bonded Turn	trans	-54.1	-27.8	174.6	-148.6	91.6	0	0	0	111.5	I633 F636 K637 Y669 I678	I633-L680 HydrophobicContact CB-CD2 4.31Å; I633-L680 HydrophobicContact CG1-CD2 4.27Å; I633-L680 HydrophobicContact CG2-CD2 3.75Å; I633-L680 HydrophobicContact CG2-CG 4.24Å; F636-L680 HydrophobicContact CB-CD2 4.29Å; F636-L680 HydrophobicContact CD2-CD2 4.49Å; K637-L680 WeakPolarHBondContact CE-O 3.46Å; Y669-L680 HydrophobicContact CE2-CD2 4.27Å; I678-L680 PolarHBondContact O-N 3.41Å
681	E	56.9	Low	54.2	Low	100 Å²	100	73 Å²	73	47%	0.467	41%	0.413	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.1	-42.5	173.3	-66.8	169	-148	0	0	113.5	T640 S679 L683	T640-E681 HydrophobicContact CG2-CG 4.09Å; T640-E681 WeakPolarHBondContact CG2-OE1 3.3Å; S679-E681 PolarHBondContact O-N 3.4Å; E681-L683 VanDerWaalsContact C-N 3.32Å
682	S	60.6	Low	54	Low	77 Å²	77	69 Å²	69	54%	0.538	39%	0.385	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.8	-20.4	-177.2	66.3	0	0	0	0	112.8	S679 T684	S679-S682 PolarHBondContact O-N 3.25Å; S679-S682 PolarHBondContact O-OG 2.94Å; S679-S682 WeakPolarHBondContact OG-CB 3.46Å; S679-S682 PolarHBondContact OG-OG 3.17Å; S682-T684 PolarHBondContact O-N 3.07Å
683	L	57.1	Low	54	Low	17 Å²	17	71.9 Å²	71.9	9%	0.089	41%	0.407	C	S	.	.	S	Bend	trans	-71.5	128.9	179.7	-69.1	174.7	0	0	0	110.6	K637 I678 S679 E681 E687 I688 I691 I702	K637-L683 PolarHBondContact NZ-O 2.95Å; I678-L683 HydrophobicContact CG2-CD1 3.56Å; I678-L683 HydrophobicContact CG2-CD2 3.64Å; I678-L683 HydrophobicContact CG2-CG 3.54Å; S679-L683 PolarHBondContact O-N 2.85Å; E681-L683 VanDerWaalsContact C-N 3.32Å; L683-E687 VanDerWaalsContact CA-OE2 3.27Å; L683-E687 WeakPolarHBondContact CA-OE2 3.4Å; L683-E687 HydrophobicContact CD2-CB 4Å; L683-I688 HydrophobicContact CB-CD1 4.1Å; L683-I688 HydrophobicContact CB-CG1 3.87Å; L683-I688 HydrophobicContact CD1-CG1 4.06Å; L683-I691 HydrophobicContact CD1-CD1 4.13Å; L683-I691 HydrophobicContact CD2-CD1 4.11Å; L683-I702 HydrophobicContact CD1-CD1 4.2Å
684	T	63.6	Low	54.3	Low	68 Å²	68	69.2 Å²	69.2	42%	0.417	39%	0.393	S	S	.	.			trans	-67.6	155.9	166.1	64.6	0	0	0	0	110.4	S682 K686 E687 I688	S682-T684 PolarHBondContact O-N 3.07Å; T684-K686 PolarHBondContact O-N 3.4Å; T684-K686 VanDerWaalsContact O-N 3.14Å; T684-E687 PolarHBondContact N-OE2 2.68Å; T684-E687 PolarHBondContact O-N 2.89Å; T684-E687 VanDerWaalsContact OG1-CG 3.27Å; T684-E687 WeakPolarHBondContact OG1-CG 3.13Å; T684-E687 PolarHBondContact OG1-N 3.44Å; T684-E687 VanDerWaalsContact OG1-N 3.1Å; T684-E687 PolarHBondContact OG1-OE2 3.33Å; T684-I688 WeakPolarHBondContact O-CD1 3.46Å; T684-I688 WeakPolarHBondContact O-CG1 3.41Å; T684-I688 PolarHBondContact O-N 3.09Å
685	M	62	Low	54.6	Low	38 Å²	38	68 Å²	68	19%	0.187	39%	0.392	C	S	.	.	H	α-helix	trans	-57.9	-27.4	173.6	-75.4	-56.9	-62.6	0	0	112.4	E630 L634 I688 Q689	E630-M685 HydrophobicContact CB-CE 4.12Å; E630-M685 HydrophobicContact CG-CE 4.26Å; L634-M685 HydrophobicContact CD1-CE 4.19Å; L634-M685 HydrophobicContact CD2-CE 4.24Å; L634-M685 HydrophobicContact CD2-CG 4.29Å; L634-M685 HydrophobicContact CD2-SD 3.65Å; L634-M685 HydrophobicContact CG-CE 4.04Å; L634-M685 HydrophobicContact CG-SD 3.97Å; M685-I688 HydrophobicContact SD-CD1 3.86Å; M685-Q689 VanDerWaalsContact O-CG 3.29Å; M685-Q689 WeakPolarHBondContact O-CG 3.29Å; M685-Q689 PolarHBondContact O-N 3.26Å
686	K	57.9	Low	54.9	Low	78 Å²	78	69.4 Å²	69.4	34%	0.339	40%	0.4	S	S	.	.	H	α-helix	trans	-72	-46.4	175.7	-170.3	-174.9	-176.7	173.3	0	112	Y456 T684 I688 Q689 E690	Y456-K686 WeakPolarHBondContact OH-CD 3.47Å; Y456-K686 WeakPolarHBondContact OH-CE 2.99Å; Y456-K686 PolarHBondContact OH-NZ 3.35Å; T684-K686 PolarHBondContact O-N 3.4Å; T684-K686 VanDerWaalsContact O-N 3.14Å; K686-I688 PolarHBondContact O-N 3.11Å; K686-Q689 CarbonylContact O-C 3.15Å; K686-Q689 WeakPolarHBondContact O-CB 3.43Å; K686-Q689 PolarHBondContact O-N 3.34Å; K686-Q689 VanDerWaalsContact O-N 3.07Å; K686-E690 VanDerWaalsContact CE-OE1 3.23Å; K686-E690 WeakPolarHBondContact CE-OE1 3.43Å; K686-E690 HydrophobicContact CG-CG 4.48Å; K686-E690 WeakPolarHBondContact O-CB 2.94Å; K686-E690 WeakPolarHBondContact O-CG 3.18Å; K686-E690 PolarHBondContact O-N 2.77Å
687	E	59.9	Low	55.1	Low	81 Å²	81	67.5 Å²	67.5	38%	0.379	39%	0.385	S	S	.	.	H	α-helix	trans	-59.7	-39.9	173.8	-72.4	164.8	156.8	0	0	110.7	L683 T684 Q689 E690 I691	L683-E687 VanDerWaalsContact CA-OE2 3.27Å; L683-E687 WeakPolarHBondContact CA-OE2 3.4Å; L683-E687 HydrophobicContact CD2-CB 4Å; T684-E687 PolarHBondContact N-OE2 2.68Å; T684-E687 PolarHBondContact O-N 2.89Å; T684-E687 VanDerWaalsContact OG1-CG 3.27Å; T684-E687 WeakPolarHBondContact OG1-CG 3.13Å; T684-E687 PolarHBondContact OG1-N 3.44Å; T684-E687 VanDerWaalsContact OG1-N 3.1Å; T684-E687 PolarHBondContact OG1-OE2 3.33Å; E687-Q689 PolarHBondContact O-N 3.16Å; E687-E690 PolarHBondContact O-N 3.18Å; E687-I691 WeakPolarHBondContact O-CB 3.3Å; E687-I691 WeakPolarHBondContact O-CD1 3.24Å; E687-I691 WeakPolarHBondContact O-CG1 3.46Å; E687-I691 PolarHBondContact O-N 3.39Å
688	I	59.7	Low	54.9	Low	0 Å²	0	66.9 Å²	66.9	0%	0	38%	0.38	C	S	.	.	H	α-helix	trans	-58.3	-48.6	172	-71.2	155	0	0	0	110.8	I633 L683 T684 M685 K686 I691 L692	I633-I688 HydrophobicContact CD1-CG2 3.41Å; I633-I688 VanDerWaalsContact CD1-CG2 3.41Å; I633-I688 HydrophobicContact CG2-CD1 3.5Å; I633-I688 HydrophobicContact CG2-CG1 4.38Å; L683-I688 HydrophobicContact CB-CD1 4.1Å; L683-I688 HydrophobicContact CB-CG1 3.87Å; L683-I688 HydrophobicContact CD1-CG1 4.06Å; T684-I688 WeakPolarHBondContact O-CD1 3.46Å; T684-I688 WeakPolarHBondContact O-CG1 3.41Å; T684-I688 PolarHBondContact O-N 3.09Å; M685-I688 HydrophobicContact SD-CD1 3.86Å; K686-I688 PolarHBondContact O-N 3.11Å; I688-I691 PolarHBondContact O-N 3.01Å; I688-L692 HydrophobicContact CG2-CD1 3.77Å; I688-L692 HydrophobicContact CG2-CG 4.34Å; I688-L692 WeakPolarHBondContact O-CB 3.38Å; I688-L692 WeakPolarHBondContact O-CG 3.48Å; I688-L692 PolarHBondContact O-N 3.43Å
689	Q	56.5	Low	54.8	Low	74 Å²	74	66.9 Å²	66.9	35%	0.346	39%	0.386	S	S	.	.	H	α-helix	trans	-63.1	-43.1	177.6	-77.8	174.6	-10	0	0	112.7	E630 M685 K686 E687 I691 L692 C693	E630-Q689 VanDerWaalsContact OE1-CG 3.27Å; E630-Q689 WeakPolarHBondContact OE1-CG 3.41Å; E630-Q689 PolarHBondContact OE1-NE2 2.91Å; M685-Q689 VanDerWaalsContact O-CG 3.29Å; M685-Q689 WeakPolarHBondContact O-CG 3.29Å; M685-Q689 PolarHBondContact O-N 3.26Å; K686-Q689 CarbonylContact O-C 3.15Å; K686-Q689 WeakPolarHBondContact O-CB 3.43Å; K686-Q689 PolarHBondContact O-N 3.34Å; K686-Q689 VanDerWaalsContact O-N 3.07Å; E687-Q689 PolarHBondContact O-N 3.16Å; Q689-I691 VanDerWaalsContact C-N 3.33Å; Q689-I691 PolarHBondContact O-N 2.91Å; Q689-L692 PolarHBondContact O-N 3.09Å; Q689-C693 VanDerWaalsContact O-CB 3.23Å; Q689-C693 WeakPolarHBondContact O-CB 3.4Å; Q689-C693 PolarHBondContact O-N 3.31Å; Q689-C693 PolarHBondContact O-SG 3.04Å; Q689-C693 VanDerWaalsContact O-SG 3.34Å
690	E	58.1	Low	54.6	Low	112 Å²	112	64.2 Å²	64.2	52%	0.523	37%	0.368	S	S	.	.	H	α-helix	trans	-62.4	-41.7	177	-74.2	175.5	-174.9	0	0	110.9	K686 E687 S694	K686-E690 VanDerWaalsContact CE-OE1 3.23Å; K686-E690 WeakPolarHBondContact CE-OE1 3.43Å; K686-E690 HydrophobicContact CG-CG 4.48Å; K686-E690 WeakPolarHBondContact O-CB 2.94Å; K686-E690 WeakPolarHBondContact O-CG 3.18Å; K686-E690 PolarHBondContact O-N 2.77Å; E687-E690 PolarHBondContact O-N 3.18Å; E690-S694 WeakPolarHBondContact O-CB 3.24Å; E690-S694 PolarHBondContact O-N 2.97Å
691	I	59.4	Low	54.8	Low	50 Å²	50	65.9 Å²	65.9	26%	0.256	39%	0.388	S	S	.	.	H	α-helix	trans	-62.4	-48.9	172.9	-66.1	161.6	0	0	0	109.9	L683 E687 I688 Q689 C693 S694 T700 I702	L683-I691 HydrophobicContact CD1-CD1 4.13Å; L683-I691 HydrophobicContact CD2-CD1 4.11Å; E687-I691 WeakPolarHBondContact O-CB 3.3Å; E687-I691 WeakPolarHBondContact O-CD1 3.24Å; E687-I691 WeakPolarHBondContact O-CG1 3.46Å; E687-I691 PolarHBondContact O-N 3.39Å; I688-I691 PolarHBondContact O-N 3.01Å; Q689-I691 VanDerWaalsContact C-N 3.33Å; Q689-I691 PolarHBondContact O-N 2.91Å; I691-C693 PolarHBondContact O-N 3.33Å; I691-S694 PolarHBondContact O-N 3.21Å; I691-S694 PolarHBondContact O-OG 2.98Å; I691-T700 HydrophobicContact CG2-CG2 4.35Å; I691-T700 WeakPolarHBondContact O-CG2 3.22Å; I691-I702 HydrophobicContact CB-CD1 4.33Å; I691-I702 HydrophobicContact CD1-CD1 3.98Å; I691-I702 HydrophobicContact CG2-CD1 3.7Å; I691-I702 HydrophobicContact CG2-CG1 4.31Å
692	L	54.3	Low	54.9	Low	7 Å²	7	61.7 Å²	61.7	4%	0.037	37%	0.369	C	S	.	.	H	α-helix	trans	-67.2	-34.1	-178.2	-69.9	174.1	0	0	0	113.9	I626 I629 E630 I633 I688 Q689 T703	I626-L692 HydrophobicContact CG2-CD1 4.26Å; I629-L692 HydrophobicContact CB-CD1 4.37Å; I629-L692 HydrophobicContact CD1-CD2 4.39Å; I629-L692 HydrophobicContact CG2-CD1 3.79Å; I629-L692 HydrophobicContact CG2-CD2 3.74Å; I629-L692 HydrophobicContact CG2-CG 4.44Å; E630-L692 HydrophobicContact CG-CD1 4.31Å; I633-L692 HydrophobicContact CD1-CD1 4.48Å; I688-L692 HydrophobicContact CG2-CD1 3.77Å; I688-L692 HydrophobicContact CG2-CG 4.34Å; I688-L692 WeakPolarHBondContact O-CB 3.38Å; I688-L692 WeakPolarHBondContact O-CG 3.48Å; I688-L692 PolarHBondContact O-N 3.43Å; Q689-L692 PolarHBondContact O-N 3.09Å; L692-T703 WeakPolarHBondContact CD2-OG1 3.32Å
693	C	52.8	Low	54.9	Low	93 Å²	93	58.7 Å²	58.7	63%	0.628	35%	0.347	S	S	*	.	H	α-helix	trans	-86.3	-11.3	179.1	-68.6	0	0	0	0	113.3	Q689 I691	Q689-C693 VanDerWaalsContact O-CB 3.23Å; Q689-C693 WeakPolarHBondContact O-CB 3.4Å; Q689-C693 PolarHBondContact O-N 3.31Å; Q689-C693 PolarHBondContact O-SG 3.04Å; Q689-C693 VanDerWaalsContact O-SG 3.34Å; I691-C693 PolarHBondContact O-N 3.33Å
694	S	52.5	Low	55.2	Low	59 Å²	59	62.5 Å²	62.5	41%	0.413	37%	0.367	S	S	.	.	S	Bend	trans	-63	144.8	172.5	73.2	0	0	0	0	111.1	E690 I691 N696	E690-S694 WeakPolarHBondContact O-CB 3.24Å; E690-S694 PolarHBondContact O-N 2.97Å; I691-S694 PolarHBondContact O-N 3.21Å; I691-S694 PolarHBondContact O-OG 2.98Å; S694-N696 PolarHBondContact O-N 3.19Å
695	V	43.4	Very low	55.2	Low	132 Å²	132	60.9 Å²	60.9	80%	0.8	35%	0.354	S	S	*	.	S	Bend	trans	-47.3	119.4	-165.4	-177.5	0	0	0	0	112.4	S699	V695-S699 PolarHBondContact O-OG 3.3Å
696	N	46	Very low	55.4	Low	98 Å²	98	59.2 Å²	59.2	52%	0.524	35%	0.345	S	S	.	.			trans	79.8	99.6	-175.6	-73.6	-21.1	0	0	0	116.6	S694 S698 S699	S694-N696 PolarHBondContact O-N 3.19Å; N696-S698 PolarHBondContact O-N 3.01Å; N696-S698 VanDerWaalsContact O-N 3.14Å; N696-S699 WeakPolarHBondContact CB-OG 3.34Å; N696-S699 WeakPolarHBondContact O-CB 3.47Å; N696-S699 PolarHBondContact O-N 3.02Å; N696-S699 PolarHBondContact O-OG 3.35Å
697	P	46.2	Very low	55.7	Low	82 Å²	82	56.8 Å²	56.8	53%	0.532	34%	0.336	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.9	-19.8	171.7	23.3	-32.2	0	0	0	113.8	S699	P697-S699 VanDerWaalsContact C-N 3.26Å; P697-S699 PolarHBondContact O-N 3.4Å
698	S	43.3	Very low	56.1	Low	88 Å²	88	54.9 Å²	54.9	62%	0.615	33%	0.331	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.3	-8.8	171.4	54.1	0	0	0	0	114.2	N696	N696-S698 PolarHBondContact O-N 3.01Å; N696-S698 VanDerWaalsContact O-N 3.14Å
699	S	46.2	Very low	56.5	Low	71 Å²	71	54.9 Å²	54.9	50%	0.497	33%	0.332	S	S	.	.	T	Hydrogen-bonded Turn	trans	-111.3	-8.9	-173	75.5	0	0	0	0	114.8	V695 N696 P697 G701	V695-S699 PolarHBondContact O-OG 3.3Å; N696-S699 WeakPolarHBondContact CB-OG 3.34Å; N696-S699 WeakPolarHBondContact O-CB 3.47Å; N696-S699 PolarHBondContact O-N 3.02Å; N696-S699 PolarHBondContact O-OG 3.35Å; P697-S699 VanDerWaalsContact C-N 3.26Å; P697-S699 PolarHBondContact O-N 3.4Å; S699-G701 PolarHBondContact O-N 3.24Å
700	T	53.5	Low	56.9	Low	9 Å²	9	51.8 Å²	51.8	6%	0.055	32%	0.317	C	S	.	.			trans	-82.6	120.2	-180	52	0	0	0	0	109.5	I691 I702 T703 L704	I691-T700 HydrophobicContact CG2-CG2 4.35Å; I691-T700 WeakPolarHBondContact O-CG2 3.22Å; T700-I702 PolarHBondContact O-N 3.27Å; T700-T703 PolarHBondContact O-N 2.91Å; T700-T703 PolarHBondContact OG1-OG1 2.98Å; T700-L704 PolarHBondContact O-N 3.2Å
701	G	60.1	Low	57.4	Low	49 Å²	49	51.7 Å²	51.7	51%	0.505	32%	0.317	S	S	.	.	H	α-helix	trans	-54	-29.5	-178.2	0	0	0	0	0	113.8	S699 Y705	S699-G701 PolarHBondContact O-N 3.24Å; G701-Y705 WeakPolarHBondContact O-CB 3.47Å; G701-Y705 PolarHBondContact O-N 3.24Å
702	I	60.5	Low	57.7	Low	13 Å²	13	53.9 Å²	53.9	7%	0.067	33%	0.329	C	S	.	.	H	α-helix	trans	-64.5	-42.6	175.1	-60.1	-178.3	0	0	0	111.8	I633 L683 I691 T700 Y705 I706	I633-I702 HydrophobicContact CD1-CG2 4.03Å; L683-I702 HydrophobicContact CD1-CD1 4.2Å; I691-I702 HydrophobicContact CB-CD1 4.33Å; I691-I702 HydrophobicContact CD1-CD1 3.98Å; I691-I702 HydrophobicContact CG2-CD1 3.7Å; I691-I702 HydrophobicContact CG2-CG1 4.31Å; T700-I702 PolarHBondContact O-N 3.27Å; I702-Y705 PolarHBondContact O-N 3.07Å; I702-I706 HydrophobicContact CG2-CD1 3.72Å; I702-I706 HydrophobicContact CG2-CG1 4.47Å; I702-I706 WeakPolarHBondContact O-CB 3.34Å; I702-I706 VanDerWaalsContact O-CG1 3.3Å; I702-I706 WeakPolarHBondContact O-CG1 3.22Å; I702-I706 PolarHBondContact O-N 3.4Å
703	T	59.4	Low	58.2	Low	13 Å²	13	55.9 Å²	55.9	8%	0.08	34%	0.339	C	S	.	.	H	α-helix	trans	-68.4	-44.8	-178.4	-54.3	0	0	0	0	110.9	I629 L692 T700 Y705 I706 I707	I629-T703 HydrophobicContact CD1-CG2 3.82Å; L692-T703 WeakPolarHBondContact CD2-OG1 3.32Å; T700-T703 PolarHBondContact O-N 2.91Å; T700-T703 PolarHBondContact OG1-OG1 2.98Å; T703-Y705 VanDerWaalsContact C-N 3.32Å; T703-Y705 PolarHBondContact O-N 2.71Å; T703-I706 PolarHBondContact O-N 3.38Å; T703-I707 HydrophobicContact CG2-CD1 4.06Å; T703-I707 VanDerWaalsContact O-CG1 3.26Å; T703-I707 WeakPolarHBondContact O-CG1 3.45Å; T703-I707 PolarHBondContact O-N 3.49Å
704	L	63.1	Low	58.5	Low	98 Å²	98	54 Å²	54	51%	0.513	33%	0.325	S	S	.	.	H	α-helix	trans	-62.3	-40.2	175.3	-70.4	172.8	0	0	0	111.7	T700 I707 S708	T700-L704 PolarHBondContact O-N 3.2Å; L704-I707 PolarHBondContact O-N 3.49Å; L704-S708 PolarHBondContact O-N 3.38Å; L704-S708 PolarHBondContact O-OG 3.14Å
705	Y	64.4	Low	58.8	Low	33 Å²	33	53.7 Å²	53.7	13%	0.129	32%	0.32	C	S	.	.	H	α-helix	trans	-62.2	-46	175.6	176.4	-105	0	0	0	112.4	Y669 Q672 G701 I702 T703 I707 S708 I709	Y669-Y705 HydrophobicContact CD2-CE1 4.43Å; Q672-Y705 HydrophobicContact CB-CE2 3.77Å; Q672-Y705 PolarHBondContact O-OH 3.23Å; Q672-Y705 VanDerWaalsContact O-OH 3.09Å; Q672-Y705 VanDerWaalsContact OE1-CE2 3.23Å; G701-Y705 WeakPolarHBondContact O-CB 3.47Å; G701-Y705 PolarHBondContact O-N 3.24Å; I702-Y705 PolarHBondContact O-N 3.07Å; T703-Y705 VanDerWaalsContact C-N 3.32Å; T703-Y705 PolarHBondContact O-N 2.71Å; Y705-I707 VanDerWaalsContact C-N 3.31Å; Y705-I707 PolarHBondContact O-N 3.02Å; Y705-S708 WeakPolarHBondContact CA-OG 3.41Å; Y705-S708 PolarHBondContact O-N 3.19Å; Y705-S708 VanDerWaalsContact O-N 3.16Å; Y705-S708 PolarHBondContact O-OG 2.96Å; Y705-I709 HydrophobicContact CD1-CD1 3.79Å; Y705-I709 HydrophobicContact CE1-CD1 3.26Å; Y705-I709 HydrophobicContact CE1-CG1 4.31Å; Y705-I709 HydrophobicContact CE2-CD1 4.28Å; Y705-I709 HydrophobicContact CG-CD1 4.47Å; Y705-I709 WeakPolarHBondContact O-CG1 3.37Å; Y705-I709 PolarHBondContact O-N 3.05Å
706	I	65.4	Low	59.6	Low	3 Å²	3	49.4 Å²	49.4	2%	0.015	29%	0.293	C	S	.	.	H	α-helix	trans	-64.1	-39.5	176.8	-72.8	168.6	0	0	0	110.8	I629 L632 I633 I702 T703 I709 L710	I629-I706 HydrophobicContact CG2-CD1 3.44Å; I629-I706 VanDerWaalsContact CG2-CD1 3.44Å; L632-I706 HydrophobicContact CB-CG2 4.36Å; L632-I706 HydrophobicContact CD1-CG2 3.43Å; L632-I706 VanDerWaalsContact CD1-CG2 3.43Å; I633-I706 HydrophobicContact CD1-CD1 3.86Å; I633-I706 HydrophobicContact CG1-CD1 3.63Å; I702-I706 HydrophobicContact CG2-CD1 3.72Å; I702-I706 HydrophobicContact CG2-CG1 4.47Å; I702-I706 WeakPolarHBondContact O-CB 3.34Å; I702-I706 VanDerWaalsContact O-CG1 3.3Å; I702-I706 WeakPolarHBondContact O-CG1 3.22Å; I702-I706 PolarHBondContact O-N 3.4Å; T703-I706 PolarHBondContact O-N 3.38Å; I706-I709 PolarHBondContact O-N 3.11Å; I706-L710 HydrophobicContact CG2-CD1 4.31Å; I706-L710 WeakPolarHBondContact O-CG 3.17Å; I706-L710 PolarHBondContact O-N 2.85Å
707	I	64.9	Low	60.4	Low	28 Å²	28	46.5 Å²	46.5	14%	0.144	28%	0.28	C	S	.	.	H	α-helix	trans	-62.4	-43.1	173	-68	167.3	0	0	0	110.6	T703 L704 Y705 I709 L710 E711	T703-I707 HydrophobicContact CG2-CD1 4.06Å; T703-I707 VanDerWaalsContact O-CG1 3.26Å; T703-I707 WeakPolarHBondContact O-CG1 3.45Å; T703-I707 PolarHBondContact O-N 3.49Å; L704-I707 PolarHBondContact O-N 3.49Å; Y705-I707 VanDerWaalsContact C-N 3.31Å; Y705-I707 PolarHBondContact O-N 3.02Å; I707-I709 VanDerWaalsContact C-N 3.34Å; I707-I709 PolarHBondContact O-N 2.98Å; I707-L710 PolarHBondContact O-N 2.98Å; I707-L710 VanDerWaalsContact O-N 3.15Å; I707-E711 HydrophobicContact CG2-CG 4.43Å; I707-E711 WeakPolarHBondContact O-CG 3.34Å; I707-E711 PolarHBondContact O-N 3.07Å
708	S	68.3	Low	61.3	Low	40 Å²	40	44.3 Å²	44.3	28%	0.28	26%	0.264	S	S	.	.	H	α-helix	trans	-63.5	-38.3	177.1	57.1	0	0	0	0	112.6	L704 Y705 L710 E711 D712	L704-S708 PolarHBondContact O-N 3.38Å; L704-S708 PolarHBondContact O-OG 3.14Å; Y705-S708 WeakPolarHBondContact CA-OG 3.41Å; Y705-S708 PolarHBondContact O-N 3.19Å; Y705-S708 VanDerWaalsContact O-N 3.16Å; Y705-S708 PolarHBondContact O-OG 2.96Å; S708-L710 VanDerWaalsContact C-N 3.35Å; S708-E711 PolarHBondContact O-N 3Å; S708-D712 PolarHBondContact O-N 3.25Å
709	I	67.4	Low	62.5	Low	1 Å²	1	41.4 Å²	41.4	1%	0.005	24%	0.241	C	C	.	.	H	α-helix	trans	-61.9	-44.5	172.8	-66.9	169.5	0	0	0	110.5	F636 V668 Y705 I706 I707 E711 D712 I713	F636-I709 HydrophobicContact CE1-CG2 4.47Å; F636-I709 HydrophobicContact CE2-CD1 3.96Å; F636-I709 HydrophobicContact CZ-CD1 3.81Å; F636-I709 HydrophobicContact CZ-CG2 3.86Å; V668-I709 HydrophobicContact CG1-CB 4.23Å; V668-I709 HydrophobicContact CG1-CG1 4.09Å; V668-I709 HydrophobicContact CG1-CG2 3.78Å; Y705-I709 HydrophobicContact CD1-CD1 3.79Å; Y705-I709 HydrophobicContact CE1-CD1 3.26Å; Y705-I709 HydrophobicContact CE1-CG1 4.31Å; Y705-I709 HydrophobicContact CE2-CD1 4.28Å; Y705-I709 HydrophobicContact CG-CD1 4.47Å; Y705-I709 WeakPolarHBondContact O-CG1 3.37Å; Y705-I709 PolarHBondContact O-N 3.05Å; I706-I709 PolarHBondContact O-N 3.11Å; I707-I709 VanDerWaalsContact C-N 3.34Å; I707-I709 PolarHBondContact O-N 2.98Å; I709-E711 VanDerWaalsContact C-N 3.29Å; I709-E711 PolarHBondContact O-N 3.34Å; I709-D712 PolarHBondContact O-N 3.17Å; I709-I713 HydrophobicContact CG2-CD1 3.72Å; I709-I713 HydrophobicContact CG2-CG1 4.46Å; I709-I713 WeakPolarHBondContact O-CD1 3.39Å; I709-I713 VanDerWaalsContact O-CG1 3.23Å; I709-I713 WeakPolarHBondContact O-CG1 3.31Å; I709-I713 PolarHBondContact O-N 3.15Å; I709-I713 VanDerWaalsContact O-N 3.14Å
710	L	66.1	Low	63.7	Low	9 Å²	9	39.3 Å²	39.3	5%	0.047	22%	0.222	C	C	.	.	H	α-helix	trans	-65.4	-29.7	177.9	-71.7	173.2	0	0	0	113.1	L614 W617 L624 L632 I706 I707 S708	L614-L710 HydrophobicContact CD2-CD2 3.6Å; W617-L710 HydrophobicContact CB-CD1 4.29Å; W617-L710 HydrophobicContact CE3-CD2 4.41Å; L624-L710 HydrophobicContact CD2-CD1 4.02Å; L632-L710 HydrophobicContact CD1-CD1 3.88Å; L632-L710 HydrophobicContact CD1-CD2 3.97Å; L632-L710 HydrophobicContact CD1-CG 4.08Å; L632-L710 HydrophobicContact CD2-CD2 4.48Å; I706-L710 HydrophobicContact CG2-CD1 4.31Å; I706-L710 WeakPolarHBondContact O-CG 3.17Å; I706-L710 PolarHBondContact O-N 2.85Å; I707-L710 PolarHBondContact O-N 2.98Å; I707-L710 VanDerWaalsContact O-N 3.15Å; S708-L710 VanDerWaalsContact C-N 3.35Å
711	E	68.4	Low	64.5	Low	109 Å²	109	41.6 Å²	41.6	51%	0.509	24%	0.235	S	C	.	.	H	α-helix	trans	-72.5	-41.3	174.9	-74.4	-172.8	160.7	0	0	112.2	K618 I707 S708 I709 I713	K618-E711 PolarHBondContact NZ-O 2.94Å; I707-E711 HydrophobicContact CG2-CG 4.43Å; I707-E711 WeakPolarHBondContact O-CG 3.34Å; I707-E711 PolarHBondContact O-N 3.07Å; S708-E711 PolarHBondContact O-N 3Å; I709-E711 VanDerWaalsContact C-N 3.29Å; I709-E711 PolarHBondContact O-N 3.34Å; E711-I713 VanDerWaalsContact C-N 3.3Å; E711-I713 PolarHBondContact O-N 2.59Å
712	D	66.2	Low	64.8	Low	97 Å²	97	41 Å²	41	52%	0.519	21%	0.213	S	C	.	.	H	α-helix	trans	-67.4	-26.5	177.8	-79.2	-5.4	0	0	0	113.5	K664 V668 Q672 S708 I709	K664-D712 PolarHBondContact NZ-O 3.22Å; V668-D712 HydrophobicContact CG1-CB 4.17Å; Q672-D712 PolarHBondContact NE2-OD2 3.11Å; S708-D712 PolarHBondContact O-N 3.25Å; I709-D712 PolarHBondContact O-N 3.17Å
713	I	64	Low	65.2	Low	48 Å²	48	43.5 Å²	43.5	25%	0.246	23%	0.226	C	C	.	.			trans	-76	0	174.6	-65.7	163	0	0	0	111	L614 K618 K664 L665 I709 E711	L614-I713 HydrophobicContact CD1-CG2 4.38Å; K618-I713 PolarHBondContact NZ-OXT 3.18Å; K664-I713 PolarHBondContact NZ-O 3Å; L665-I713 HydrophobicContact CD2-CD1 3.3Å; L665-I713 HydrophobicContact CG-CD1 3.94Å; I709-I713 HydrophobicContact CG2-CD1 3.72Å; I709-I713 HydrophobicContact CG2-CG1 4.46Å; I709-I713 WeakPolarHBondContact O-CD1 3.39Å; I709-I713 VanDerWaalsContact O-CG1 3.23Å; I709-I713 WeakPolarHBondContact O-CG1 3.31Å; I709-I713 PolarHBondContact O-N 3.15Å; I709-I713 VanDerWaalsContact O-N 3.14Å; E711-I713 VanDerWaalsContact C-N 3.3Å; E711-I713 PolarHBondContact O-N 2.59Å

Retrieved 713 of 713 residues in 526.5 ms (Link to these results)

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