A0A3Q0KV37_SCHMA Loading...

Putative annexin

AlphaFold DB , UniProt , Accession A0A3Q0KV37, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 472 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	39.2	Very low	39.5	Very low	230 Å²	230	151.2 Å²	151.2	100%	1.133	85%	0.849	S	S	*	*				0	83.8	0	-69.5	174.5	173.3	0	0	108.1
2	D	39.3	Very low	38.9	Very low	161 Å²	161	156.2 Å²	156.2	86%	0.861	86%	0.856	S	S	*	*			trans	52	106.1	132.6	-40.8	-46.9	0	0	0	121.1
3	G	40.7	Very low	39	Very low	76 Å²	76	153.5 Å²	153.5	78%	0.784	86%	0.856	S	S	*	*				121.5	143.3	120.2	0	0	0	0	0	117.3
4	K	45.2	Very low	38.8	Very low	200 Å²	200	147.1 Å²	147.1	87%	0.87	84%	0.841	S	S	*	*			cis	-159.4	139.4	-19.6	-148.5	173.5	-174.2	177.3	0	108.8
5	I	34.6	Very low	38.7	Very low	153 Å²	153	150.1 Å²	150.1	79%	0.785	85%	0.845	S	S	*	*			trans	-81.6	137	175.9	-62.6	166.7	0	0	0	109.3
6	I	49.2	Very low	38.7	Very low	147 Å²	147	146.4 Å²	146.4	75%	0.754	83%	0.832	S	S	*	*			trans	-133.8	114.8	160.5	-58	-178.4	0	0	0	108.6
7	T	33.6	Very low	38.7	Very low	129 Å²	129	146 Å²	146	79%	0.791	83%	0.827	S	S	*	*			trans	-115.9	138.9	164.3	40.1	0	0	0	0	108.1
8	T	44.7	Very low	38.8	Very low	131 Å²	131	144.3 Å²	144.3	80%	0.804	82%	0.82	S	S	*	*			trans	-138	138.9	174.6	-27.4	0	0	0	0	110.3
9	S	37.8	Very low	38.9	Very low	116 Å²	116	144.6 Å²	144.6	81%	0.811	82%	0.819	S	S	*	*			trans	-85.2	163.6	-169	-48.5	0	0	0	0	113.8
10	C	30	Very low	39	Very low	123 Å²	123	142.4 Å²	142.4	83%	0.831	81%	0.813	S	S	*	*			trans	-92	142.3	160.6	-65.2	0	0	0	0	110.2
11	E	40.3	Very low	39.1	Very low	197 Å²	197	141.9 Å²	141.9	92%	0.921	81%	0.808	S	S	*	*			trans	-136.3	158.4	156.3	-70	-163.4	152.8	0	0	109.2
12	F	32.7	Very low	39.2	Very low	211 Å²	211	138.6 Å²	138.6	93%	0.925	79%	0.792	S	S	*	*			trans	-146.9	115.8	-161	-143.8	-71.1	0	0	0	112.3
13	S	40.1	Very low	39.2	Very low	122 Å²	122	137.2 Å²	137.2	85%	0.853	79%	0.789	S	S	*	*			trans	-169.5	156.9	170.3	52.5	0	0	0	0	109.4
14	G	35.7	Very low	39	Very low	63 Å²	63	138.5 Å²	138.5	65%	0.649	79%	0.787	S	S	*	*			cis	158.3	136.7	-8.6	0	0	0	0	0	111.1
15	Q	38	Very low	38.6	Very low	192 Å²	192	136.1 Å²	136.1	90%	0.897	79%	0.789	S	S	*	*			trans	69.3	131.7	-178.6	-63.8	159.7	-17.8	0	0	113.9
16	S	38.2	Very low	38.8	Very low	92 Å²	92	133.7 Å²	133.7	64%	0.643	79%	0.786	S	S	*	*			cis	89.3	140.9	39.5	95.9	0	0	0	0	113
17	D	38.6	Very low	38.5	Very low	139 Å²	139	133 Å²	133	74%	0.743	79%	0.788	S	S	*	*			cis	-126.5	-145.6	1.3	-74.7	-81.7	0	0	0	110.4
18	T	40.8	Very low	38.7	Very low	116 Å²	116	131.9 Å²	131.9	71%	0.712	78%	0.783	S	S	*	*			cis	-163.4	165.7	7.3	-15.8	0	0	0	0	112.3
19	N	39.6	Very low	38.3	Very low	149 Å²	149	130.5 Å²	130.5	80%	0.797	78%	0.779	S	S	*	*			trans	10.8	149.2	149.2	-57.1	-19.3	0	0	0	121.4
20	S	42.3	Very low	38.3	Very low	100 Å²	100	131.7 Å²	131.7	70%	0.699	78%	0.781	S	S	*	*			cis	-167.5	153.1	33.4	69.5	0	0	0	0	117
21	N	40.8	Very low	38.4	Very low	133 Å²	133	131 Å²	131	71%	0.711	78%	0.777	S	S	*	*			trans	70	131.4	130.8	-79.4	-2.5	0	0	0	127.4
22	M	41.4	Very low	38.6	Very low	160 Å²	160	126.8 Å²	126.8	79%	0.788	77%	0.767	S	S	*	*			trans	71.2	149	142.3	-55	-81.3	-176.7	0	0	118.3
23	T	39	Very low	38.7	Very low	132 Å²	132	124.1 Å²	124.1	81%	0.81	76%	0.762	S	S	*	*			cis	-149.3	175.1	0.1	-11.9	0	0	0	0	111.3
24	S	35.4	Very low	38.5	Very low	104 Å²	104	125 Å²	125	73%	0.727	76%	0.763	S	S	*	*			trans	-113.9	154.8	-171.4	58.4	0	0	0	0	116
25	T	38.6	Very low	38.4	Very low	150 Å²	150	128.1 Å²	128.1	92%	0.92	77%	0.771	S	S	*	*			trans	-154.6	158.7	149.5	8.6	0	0	0	0	113.3
26	S	38.7	Very low	38	Very low	102 Å²	102	124 Å²	124	71%	0.713	76%	0.764	S	S	*	*			trans	-88.9	-174.8	-179.2	49.6	0	0	0	0	111.9
27	V	42.5	Very low	37.6	Very low	131 Å²	131	126.3 Å²	126.3	79%	0.794	78%	0.778	S	S	*	*			cis	-157.2	-175	44.3	-123.1	0	0	0	0	111.1
28	P	38.3	Very low	37.1	Very low	106 Å²	106	125.5 Å²	125.5	69%	0.688	78%	0.778	S	S	*	*			trans	-133	-178.8	-130.9	41.8	-20.7	0	0	0	119.2
29	S	34.6	Very low	36.8	Very low	103 Å²	103	128 Å²	128	72%	0.72	79%	0.788	S	S	*	*			trans	61.2	119.6	144.2	64	0	0	0	0	122.6
30	V	38.1	Very low	36.2	Very low	141 Å²	141	128.7 Å²	128.7	86%	0.855	79%	0.791	S	S	*	*				-148.3	147.5	118.4	176.1	0	0	0	0	108.2
31	S	33.8	Very low	35.8	Very low	107 Å²	107	132.5 Å²	132.5	75%	0.748	80%	0.8	S	S	*	*			trans	-138.9	164.3	170.5	-59.3	0	0	0	0	109.9
32	P	42.5	Very low	35.3	Very low	110 Å²	110	131.3 Å²	131.3	71%	0.714	80%	0.802	S	S	*	*				-151.8	148.7	100.7	37	-18.9	0	0	0	118.3
33	N	36.2	Very low	34.6	Very low	154 Å²	154	135.6 Å²	135.6	82%	0.824	81%	0.81	S	S	*	*			trans	52.4	106.1	137.3	-55.1	-9.2	0	0	0	122.8
34	V	34.8	Very low	34.2	Very low	142 Å²	142	134.9 Å²	134.9	86%	0.861	81%	0.805	S	S	*	*				-138.2	141.7	129.3	-179.8	0	0	0	0	107.7
35	P	34.3	Very low	33.9	Very low	127 Å²	127	136.1 Å²	136.1	83%	0.825	81%	0.811	S	S	*	*			trans	-76.2	154.8	-165.1	-18.1	33.2	0	0	0	116.2
36	S	28.9	Very low	33.4	Very low	106 Å²	106	139.4 Å²	139.4	74%	0.741	81%	0.808	S	S	*	*			trans	-106.6	142.7	170.7	53.3	0	0	0	0	111.8
37	C	30.3	Very low	33	Very low	140 Å²	140	142 Å²	142	95%	0.946	81%	0.813	S	S	*	*			trans	-97.8	111.7	166.7	-70.6	0	0	0	0	109.3
38	T	28.7	Very low	32.3	Very low	123 Å²	123	141.7 Å²	141.7	76%	0.755	81%	0.814	S	S	*	*			trans	-82.5	142.8	171.3	46.8	0	0	0	0	110.9
39	N	33.8	Very low	31.9	Very low	169 Å²	169	140 Å²	140	90%	0.904	82%	0.815	S	S	*	*			trans	-151.9	116	151	-112.3	-23.9	0	0	0	109.4
40	N	27.8	Very low	31.4	Very low	163 Å²	163	142 Å²	142	87%	0.872	82%	0.823	S	S	*	*			trans	-86.9	126.4	176.2	-90.9	-26.8	0	0	0	109.7
41	M	32.8	Very low	31	Very low	179 Å²	179	138.1 Å²	138.1	88%	0.882	81%	0.806	S	S	*	*			trans	-135.3	115.2	150.7	-76.2	-161.4	75	0	0	110.8
42	S	31.8	Very low	30.7	Very low	109 Å²	109	138.9 Å²	138.9	76%	0.762	81%	0.812	S	S	*	*			trans	27.5	107.3	146.3	-50.1	0	0	0	0	118.7	T44	S42-T44 PolarHBondContact O-N 3.02Å
43	R	26.3	Very low	30.1	Very low	250 Å²	250	142.1 Å²	142.1	94%	0.943	82%	0.815	S	S	*	*			trans	-66.2	128	159.6	-79.9	-178.7	168.3	-170.8	-3	110.7
44	T	30.2	Very low	29.8	Very low	117 Å²	117	142.6 Å²	142.6	72%	0.718	82%	0.817	S	S	*	*			trans	-123.7	125.9	146	46.1	0	0	0	0	108.3	S42 Y46	S42-T44 PolarHBondContact O-N 3.02Å; T44-Y46 PolarHBondContact O-N 2.81Å
45	P	28.9	Very low	29.7	Very low	129 Å²	129	140.3 Å²	140.3	84%	0.838	80%	0.799	S	S	*	*			trans	-80.6	111.9	-178.9	30.6	-31.8	0	0	0	110.3
46	Y	28.9	Very low	29.6	Very low	219 Å²	219	138.7 Å²	138.7	86%	0.859	78%	0.783	S	S	*	*			trans	-79.6	128.7	171.7	-116.1	-90.2	0	0	0	110.8	T44	T44-Y46 PolarHBondContact O-N 2.81Å
47	L	29.2	Very low	29.9	Very low	156 Å²	156	138.4 Å²	138.4	82%	0.817	77%	0.767	S	S	*	*			trans	-75.5	140.3	176.3	-134.6	73.2	0	0	0	110.3	G49	L47-G49 PolarHBondContact O-N 2.75Å
48	P	27.9	Very low	29.9	Very low	126 Å²	126	142 Å²	142	82%	0.818	76%	0.76	S	S	*	*			trans	-70.7	89.4	174.6	-17.9	32.4	0	0	0	111.7	T50	P48-T50 PolarHBondContact O-N 3Å
49	G	29.4	Very low	30.1	Very low	70 Å²	70	141.2 Å²	141.2	72%	0.722	75%	0.752	S	S	*	*			trans	-72.7	122.3	175.8	0	0	0	0	0	112.2	L47 A51	L47-G49 PolarHBondContact O-N 2.75Å; G49-A51 PolarHBondContact O-N 2.8Å
50	T	25.7	Very low	30.1	Very low	145 Å²	145	139.4 Å²	139.4	89%	0.89	74%	0.738	S	S	*	*			trans	-74.4	111.3	178.5	49.7	0	0	0	0	111.8	P48	P48-T50 PolarHBondContact O-N 3Å
51	A	28.4	Very low	30.3	Very low	60 Å²	60	138.7 Å²	138.7	50%	0.496	73%	0.731	S	S	.	*			trans	-139.2	105.5	169.2	0	0	0	0	0	110.3	G49 F53	G49-A51 PolarHBondContact O-N 2.8Å; A51-F53 HydrophobicContact CB-CD2 4.33Å; A51-F53 HydrophobicContact CB-CE2 3.67Å; A51-F53 HydrophobicContact CB-CZ 3.78Å; A51-F53 VanDerWaalsContact O-CD2 3.25Å; A51-F53 WeakPolarHBondContact O-CD2 3.46Å; A51-F53 PolarHBondContact O-N 2.78Å
52	S	28	Very low	30.1	Very low	123 Å²	123	138.4 Å²	138.4	86%	0.86	73%	0.728	S	S	*	*			trans	-80.8	94.2	177.8	-58	0	0	0	0	110.1	N54	S52-N54 VanDerWaalsContact C-N 3.28Å; S52-N54 PolarHBondContact O-N 3.45Å
53	F	29.1	Very low	29.9	Very low	178 Å²	178	137 Å²	137	78%	0.781	72%	0.718	S	S	*	*			trans	-73.6	75.7	-177.7	-68.6	-76.2	0	0	0	113	A51 I55	A51-F53 HydrophobicContact CB-CD2 4.33Å; A51-F53 HydrophobicContact CB-CE2 3.67Å; A51-F53 HydrophobicContact CB-CZ 3.78Å; A51-F53 VanDerWaalsContact O-CD2 3.25Å; A51-F53 WeakPolarHBondContact O-CD2 3.46Å; A51-F53 PolarHBondContact O-N 2.78Å; F53-I55 PolarHBondContact O-N 3.45Å; F53-I55 VanDerWaalsContact O-N 3.12Å
54	N	30	Very low	30	Very low	163 Å²	163	130.6 Å²	130.6	87%	0.872	71%	0.709	S	S	*	*			trans	-79.3	88.8	173.3	-139.8	0.3	0	0	0	109.2	S52 D56	S52-N54 VanDerWaalsContact C-N 3.28Å; S52-N54 PolarHBondContact O-N 3.45Å; N54-D56 PolarHBondContact O-N 3.17Å
55	I	33.2	Very low	30.1	Very low	94 Å²	94	134.1 Å²	134.1	48%	0.482	71%	0.71	S	S	.	*			trans	-82.6	111.3	175.7	-61	176.6	0	0	0	108.5	F53 Y57	F53-I55 PolarHBondContact O-N 3.45Å; F53-I55 VanDerWaalsContact O-N 3.12Å; I55-Y57 VanDerWaalsContact C-N 3.35Å; I55-Y57 HydrophobicContact CB-CD2 4.19Å; I55-Y57 HydrophobicContact CB-CE2 3.79Å; I55-Y57 HydrophobicContact CG2-CD2 3.85Å; I55-Y57 HydrophobicContact CG2-CE1 4.32Å; I55-Y57 HydrophobicContact CG2-CE2 3.61Å; I55-Y57 HydrophobicContact CG2-CG 4.3Å; I55-Y57 VanDerWaalsContact O-CD2 3.26Å; I55-Y57 WeakPolarHBondContact O-CD2 3.38Å; I55-Y57 PolarHBondContact O-N 2.68Å
56	D	31.5	Very low	30	Very low	93 Å²	93	135.5 Å²	135.5	50%	0.497	71%	0.709	S	S	.	*			trans	-78.2	84.1	174.7	-171.6	3.5	0	0	0	111.4	N54 R58 N59	N54-D56 PolarHBondContact O-N 3.17Å; D56-R58 PolarHBondContact O-N 2.68Å; D56-R58 VanDerWaalsContact O-N 3.11Å; D56-R58 WeakPolarHBondContact OD1-CB 3.2Å; D56-R58 PolarHBondContact OD1-N 2.78Å; D56-N59 PolarHBondContact OD2-ND2 3.48Å
57	Y	36.5	Very low	30.1	Very low	100 Å²	100	129 Å²	129	39%	0.392	70%	0.701	S	S	.	*	G	3₁₀ helix	trans	-58.7	-16.7	174.5	-75.3	-84.7	0	0	0	113.7	I55 N59 Q60	I55-Y57 VanDerWaalsContact C-N 3.35Å; I55-Y57 HydrophobicContact CB-CD2 4.19Å; I55-Y57 HydrophobicContact CB-CE2 3.79Å; I55-Y57 HydrophobicContact CG2-CD2 3.85Å; I55-Y57 HydrophobicContact CG2-CE1 4.32Å; I55-Y57 HydrophobicContact CG2-CE2 3.61Å; I55-Y57 HydrophobicContact CG2-CG 4.3Å; I55-Y57 VanDerWaalsContact O-CD2 3.26Å; I55-Y57 WeakPolarHBondContact O-CD2 3.38Å; I55-Y57 PolarHBondContact O-N 2.68Å; Y57-N59 PolarHBondContact O-N 3.31Å; Y57-Q60 PolarHBondContact O-N 2.86Å
58	R	30.6	Very low	30.1	Very low	215 Å²	215	125.1 Å²	125.1	81%	0.811	70%	0.698	S	S	*	*	G	3₁₀ helix	trans	-67.9	-25.7	-174.8	-150.1	173.5	-162.2	134.8	3.9	112.9	D56	D56-R58 PolarHBondContact O-N 2.68Å; D56-R58 VanDerWaalsContact O-N 3.11Å; D56-R58 WeakPolarHBondContact OD1-CB 3.2Å; D56-R58 PolarHBondContact OD1-N 2.78Å
59	N	32.6	Very low	30	Very low	107 Å²	107	125.3 Å²	125.3	57%	0.572	69%	0.692	S	S	*	*	G	3₁₀ helix	trans	-91.8	-8.5	-179	-56.8	-43.6	0	0	0	113.8	D56 Y57	D56-N59 PolarHBondContact OD2-ND2 3.48Å; Y57-N59 PolarHBondContact O-N 3.31Å
60	Q	33.2	Very low	30	Very low	132 Å²	132	127.2 Å²	127.2	62%	0.617	69%	0.692	S	S	*	*	T	Hydrogen-bonded Turn	trans	-88.3	-11.1	179.5	-70.3	-171	-8.9	0	0	114.1	Y57 Q62	Y57-Q60 PolarHBondContact O-N 2.86Å; Q60-Q62 PolarHBondContact O-N 2.9Å
61	M	31.1	Very low	30	Very low	147 Å²	147	125.8 Å²	125.8	72%	0.724	69%	0.686	S	S	*	*	T	Hydrogen-bonded Turn	trans	-75.6	-1.8	172.9	-73.5	-173.8	162.8	0	0	114
62	Q	28.8	Very low	30.1	Very low	173 Å²	173	127.7 Å²	127.7	81%	0.808	70%	0.696	S	S	*	*			trans	-100.3	75.5	173.1	-67.5	-173.4	-3.7	0	0	111	Q60	Q60-Q62 PolarHBondContact O-N 2.9Å
63	S	29.4	Very low	30.1	Very low	81 Å²	81	131.5 Å²	131.5	57%	0.566	70%	0.697	S	S	*	*			trans	-123.8	107.8	170.6	-160.7	0	0	0	0	110.7	Y65	S63-Y65 PolarHBondContact O-N 2.68Å
64	P	28.2	Very low	29.8	Very low	114 Å²	114	130.7 Å²	130.7	74%	0.74	70%	0.701	S	S	*	*			trans	-78	101.3	177.3	30.6	-31.9	0	0	0	109.7	I66	P64-I66 PolarHBondContact O-N 2.77Å
65	Y	31.6	Very low	29.8	Very low	191 Å²	191	128.8 Å²	128.8	75%	0.749	70%	0.697	S	S	*	*			trans	-67.9	99.1	172.5	-90.2	-84.7	0	0	0	110.6	S63 A67	S63-Y65 PolarHBondContact O-N 2.68Å; Y65-A67 PolarHBondContact O-N 3.38Å
66	I	27.6	Very low	29.4	Very low	159 Å²	159	132.4 Å²	132.4	82%	0.815	71%	0.713	S	S	*	*			trans	-67.1	111.9	169.4	-62.9	171.9	0	0	0	107.7	P64 G68	P64-I66 PolarHBondContact O-N 2.77Å; I66-G68 PolarHBondContact O-N 3Å
67	A	30.8	Very low	29.3	Very low	83 Å²	83	134.3 Å²	134.3	69%	0.686	73%	0.728	S	S	*	*			trans	-65.1	104.2	174.7	0	0	0	0	0	110.2	Y65 N69	Y65-A67 PolarHBondContact O-N 3.38Å; A67-N69 PolarHBondContact O-N 3.19Å; A67-N69 VanDerWaalsContact O-N 3.15Å
68	G	29	Very low	28.7	Very low	74 Å²	74	136.2 Å²	136.2	76%	0.763	74%	0.744	S	S	*	*			trans	-68.8	106.4	177	0	0	0	0	0	111.2	I66 P70	I66-G68 PolarHBondContact O-N 3Å; G68-P70 WeakPolarHBondContact O-CD 3.39Å
69	N	24.9	Very low	28.7	Very low	129 Å²	129	136.2 Å²	136.2	69%	0.69	75%	0.746	S	S	*	*			trans	-89.9	124.2	-180	175.6	13.8	0	0	0	112.2	A67 C71	A67-N69 PolarHBondContact O-N 3.19Å; A67-N69 VanDerWaalsContact O-N 3.15Å; N69-C71 PolarHBondContact ND2-SG 3.44Å; N69-C71 VanDerWaalsContact ND2-SG 3.45Å; N69-C71 PolarHBondContact OD1-N 3.33Å; N69-C71 VanDerWaalsContact OD1-N 3.17Å; N69-C71 PolarHBondContact OD1-SG 3.09Å
70	P	30.3	Very low	28.2	Very low	110 Å²	110	141.3 Å²	141.3	71%	0.714	76%	0.763	S	S	*	*			trans	-114.9	93.1	159.7	35.4	-22	0	0	0	111.6	G68 S72	G68-P70 WeakPolarHBondContact O-CD 3.39Å; P70-S72 PolarHBondContact O-N 3.43Å
71	C	24.2	Very low	28.2	Very low	115 Å²	115	139.6 Å²	139.6	78%	0.777	77%	0.766	S	S	*	*			trans	-63.7	100.4	170.5	-75.5	0	0	0	0	112	N69	N69-C71 PolarHBondContact ND2-SG 3.44Å; N69-C71 VanDerWaalsContact ND2-SG 3.45Å; N69-C71 PolarHBondContact OD1-N 3.33Å; N69-C71 VanDerWaalsContact OD1-N 3.17Å; N69-C71 PolarHBondContact OD1-SG 3.09Å
72	S	30.9	Very low	28.2	Very low	100 Å²	100	138.1 Å²	138.1	70%	0.699	77%	0.77	S	S	*	*			trans	-150.1	98.5	166.5	59.8	0	0	0	0	115	P70	P70-S72 PolarHBondContact O-N 3.43Å
73	K	28.8	Very low	28.2	Very low	203 Å²	203	136.1 Å²	136.1	88%	0.883	77%	0.77	S	S	*	*			trans	38.2	110.9	140.1	-58.4	177.7	-178.9	178.5	0	119
74	N	23.6	Very low	28.2	Very low	161 Å²	161	138 Å²	138	86%	0.861	78%	0.78	S	S	*	*			trans	-57.5	155.6	147.2	-83.3	-7.2	0	0	0	110.7
75	P	28.4	Very low	28.3	Very low	123 Å²	123	137.5 Å²	137.5	80%	0.799	78%	0.779	S	S	*	*				-130.9	170	107.1	27.3	-12.5	0	0	0	113.7
76	Q	24.7	Very low	28.3	Very low	171 Å²	171	134.2 Å²	134.2	80%	0.799	78%	0.784	S	S	*	*			trans	-73.8	152.1	-178	-58.8	146.9	-99.5	0	0	112.9
77	T	29.9	Very low	28.4	Very low	133 Å²	133	136 Å²	136	82%	0.816	79%	0.786	S	S	*	*			trans	-145.9	115.6	149.8	49.4	0	0	0	0	110.2
78	D	24.4	Very low	28.3	Very low	139 Å²	139	138.6 Å²	138.6	74%	0.743	80%	0.798	S	S	*	*			trans	-76.8	142.3	167.7	-55.5	-82.2	0	0	0	110.4
79	Y	30.1	Very low	28.3	Very low	216 Å²	216	139.6 Å²	139.6	85%	0.847	79%	0.793	S	S	*	*			trans	-150.8	95.7	159.2	-102	-70.5	0	0	0	112.2
80	F	22.9	Very low	28.7	Very low	213 Å²	213	143.3 Å²	143.3	93%	0.934	80%	0.803	S	S	*	*			trans	-87.9	131.4	152.8	-102.2	-90.2	0	0	0	108.5
81	S	32.3	Very low	28.7	Very low	97 Å²	97	141.6 Å²	141.6	68%	0.678	81%	0.806	S	S	*	*			trans	-159.8	113.3	162.6	-83.2	0	0	0	0	112.9
82	S	31.4	Very low	28.9	Very low	115 Å²	115	142.4 Å²	142.4	80%	0.804	81%	0.811	S	S	*	*			trans	16.6	125	151.2	55.8	0	0	0	0	121.3
83	V	29.2	Very low	28.9	Very low	132 Å²	132	145.4 Å²	145.4	80%	0.8	82%	0.819	S	S	*	*			trans	-63.8	162.6	155.2	-142.7	0	0	0	0	111.1
84	P	29.3	Very low	29.1	Very low	119 Å²	119	140.8 Å²	140.8	77%	0.773	81%	0.81	S	S	*	*				-144.3	153.4	96.9	37.6	-22.3	0	0	0	116.8
85	S	29.7	Very low	29.4	Very low	104 Å²	104	138.7 Å²	138.7	73%	0.727	80%	0.803	S	S	*	*			trans	-23.2	142	171.5	58.8	0	0	0	0	120.3
86	S	31.7	Very low	29.4	Very low	122 Å²	122	140.1 Å²	140.1	85%	0.853	80%	0.804	S	S	*	*			trans	-122.2	155.4	139.5	71.1	0	0	0	0	110
87	K	30.6	Very low	29.6	Very low	196 Å²	196	137.9 Å²	137.9	85%	0.852	80%	0.796	S	S	*	*			trans	-112.8	131.1	-177.4	-65.7	176.5	-179.8	175.9	0	110.4
88	C	28.9	Very low	29.6	Very low	139 Å²	139	138.9 Å²	138.9	94%	0.939	80%	0.796	S	S	*	*			trans	-125.5	152.9	152.2	-80.2	0	0	0	0	108.8
89	S	28.4	Very low	29.9	Very low	95 Å²	95	143.1 Å²	143.1	66%	0.664	80%	0.802	S	S	*	*			trans	-144.5	-179	-175.1	-167.6	0	0	0	0	109.4
90	F	32.3	Very low	29.9	Very low	207 Å²	207	139 Å²	139	91%	0.908	79%	0.79	S	S	*	*			trans	72.1	131	-178.4	-42	-71.3	0	0	0	113.8
91	G	30.8	Very low	30.4	Very low	74 Å²	74	133 Å²	133	76%	0.763	77%	0.773	S	S	*	*			cis	-157.7	162.1	-3.3	0	0	0	0	0	111.9
92	C	28.8	Very low	30.6	Very low	132 Å²	132	134.8 Å²	134.8	89%	0.892	78%	0.779	S	S	*	*			trans	-91.2	139	-176	-50.8	0	0	0	0	111.6
93	D	31.3	Very low	30.7	Very low	162 Å²	162	136 Å²	136	87%	0.866	77%	0.767	S	S	*	*			trans	-117.5	140.6	152.1	-93.1	-47.7	0	0	0	109
94	P	32.8	Very low	31.5	Very low	107 Å²	107	132.8 Å²	132.8	70%	0.695	75%	0.749	S	S	*	*			trans	-91.5	137.6	-166	33.7	-35.1	0	0	0	114.9
95	V	30.1	Very low	32.6	Very low	116 Å²	116	127.7 Å²	127.7	70%	0.703	72%	0.715	S	S	*	*			trans	54.3	103.2	135.5	-176	0	0	0	0	117.5	I97	V95-I97 HydrophobicContact CG1-CD1 3.77Å; V95-I97 HydrophobicContact CG1-CG1 3.97Å
96	N	27.7	Very low	33.9	Very low	154 Å²	154	122.9 Å²	122.9	82%	0.824	68%	0.681	S	S	*	*			trans	-130.1	87.2	145.8	-167	-6.3	0	0	0	109.7
97	I	28.5	Very low	34.9	Very low	123 Å²	123	122 Å²	122	63%	0.631	67%	0.666	S	S	*	*			trans	-75.8	144	178.6	-66.6	159.2	0	0	0	109.1	V95	V95-I97 HydrophobicContact CG1-CD1 3.77Å; V95-I97 HydrophobicContact CG1-CG1 3.97Å
98	N	30.1	Very low	36.3	Very low	154 Å²	154	117.6 Å²	117.6	82%	0.824	65%	0.653	S	S	*	*	S	Bend	trans	94.6	32.9	-179.4	-50.3	-53.6	0	0	0	118
99	R	31.2	Very low	38	Very low	229 Å²	229	113.1 Å²	113.1	86%	0.864	62%	0.617	S	S	*	*			trans	-134.5	123.4	150.6	-72.9	-170.1	173.4	168.4	-1.1	111.2
100	E	30.8	Very low	40.4	Very low	129 Å²	129	109.8 Å²	109.8	60%	0.603	59%	0.593	S	S	*	*			trans	-60.2	141.2	161.4	-67.2	162.9	156.8	0	0	108.4	V102 K395	E100-V102 PolarHBondContact O-N 2.69Å; E100-K395 IonicContact OE1-NZ 2.78Å; E100-K395 PolarHBondContact OE1-NZ 3.09Å; E100-K395 WeakPolarHBondContact OE2-CE 3.38Å; E100-K395 IonicContact OE2-NZ 3.61Å; E100-K395 PolarHBondContact OE2-NZ 3.29Å
101	P	32.9	Very low	42.7	Very low	88 Å²	88	102.4 Å²	102.4	57%	0.571	57%	0.565	S	S	*	*			trans	-74.9	87.8	-175.4	29.9	-34.9	0	0	0	111.2	Y103	P101-Y103 HydrophobicContact CB-CD2 3.97Å; P101-Y103 HydrophobicContact CB-CE2 3.78Å; P101-Y103 PolarHBondContact O-N 3.37Å
102	V	36	Very low	45.1	Very low	133 Å²	133	98.9 Å²	98.9	81%	0.806	53%	0.529	S	S	*	.			trans	-70.9	74.9	169.6	-173	0	0	0	0	109.3	E100	E100-V102 PolarHBondContact O-N 2.69Å
103	Y	32.8	Very low	47.5	Very low	142 Å²	142	93.1 Å²	93.1	56%	0.557	49%	0.49	S	S	*	.			trans	-62.8	128.4	166	-79.3	-76.1	0	0	0	109	P101 M105 P237	P101-Y103 HydrophobicContact CB-CD2 3.97Å; P101-Y103 HydrophobicContact CB-CE2 3.78Å; P101-Y103 PolarHBondContact O-N 3.37Å; Y103-M105 PolarHBondContact O-N 3.22Å; Y103-P237 VanDerWaalsContact OH-CD 3.29Å; Y103-P237 WeakPolarHBondContact OH-CD 3.38Å
104	P	46.2	Very low	49.6	Very low	64 Å²	64	86 Å²	86	42%	0.416	45%	0.452	S	S	.	.			trans	-52	142.5	169.2	-24.1	34.3	0	0	0	109.9	F106 D107	P104-F106 PolarHBondContact O-N 3.29Å; P104-F106 VanDerWaalsContact O-N 3.15Å; P104-D107 WeakPolarHBondContact CB-OD1 3.44Å; P104-D107 WeakPolarHBondContact CG-OD2 3.31Å
105	M	53.8	Low	51.5	Low	12 Å²	12	81 Å²	81	6%	0.059	42%	0.42	C	S	.	.	S	Bend	trans	-64.3	-25.9	-175.6	-163.3	165.6	153.8	0	0	111.2	Y103 D213 F225 R232 K398 I401	Y103-M105 PolarHBondContact O-N 3.22Å; M105-D213 HydrophobicContact CB-CB 3.76Å; M105-D213 VanDerWaalsContact CB-CG 3.41Å; M105-D213 VanDerWaalsContact CB-OD2 3.31Å; M105-D213 WeakPolarHBondContact CB-OD2 3.27Å; M105-D213 HydrophobicContact CG-CB 4.16Å; M105-D213 HydrophobicContact SD-CB 3.77Å; M105-F225 HydrophobicContact CE-CE2 4.02Å; M105-F225 HydrophobicContact CE-CZ 3.77Å; M105-R232 WeakPolarHBondContact O-CD 3.31Å; M105-R232 PolarHBondContact O-NE 2.88Å; M105-R232 PolarHBondContact O-NH1 3.4Å; M105-R232 PolarHBondContact O-NH2 3.41Å; M105-K398 HydrophobicContact SD-CB 4.5Å; M105-K398 HydrophobicContact SD-CG 4.31Å; M105-I401 HydrophobicContact CE-CB 4.2Å; M105-I401 HydrophobicContact CE-CG2 3.77Å; M105-I401 HydrophobicContact SD-CD1 4.05Å
106	F	57	Low	53.1	Low	2 Å²	2	79.8 Å²	79.8	1%	0.009	41%	0.407	C	S	.	.			trans	-154.4	119.9	174.2	-47.7	-86.8	0	0	0	113	P104 F109 K212 D213 A217 F225 I228	P104-F106 PolarHBondContact O-N 3.29Å; P104-F106 VanDerWaalsContact O-N 3.15Å; F106-F109 HydrophobicContact CB-CD1 3.98Å; F106-F109 HydrophobicContact CB-CD2 4.04Å; F106-F109 HydrophobicContact CB-CE1 3.32Å; F106-F109 HydrophobicContact CB-CE2 3.39Å; F106-F109 HydrophobicContact CB-CG 4.33Å; F106-F109 HydrophobicContact CB-CZ 3.01Å; F106-F109 AromaticContact CD1-CD1 3.92Å; F106-F109 HydrophobicContact CD1-CD1 3.92Å; F106-F109 AromaticContact CD1-CE1 3.22Å; F106-F109 HydrophobicContact CD1-CE1 3.22Å; F106-F109 AromaticContact CD1-CZ 3.8Å; F106-F109 HydrophobicContact CD1-CZ 3.8Å; F106-F109 AromaticContact CD2-CE1 3.69Å; F106-F109 HydrophobicContact CD2-CE1 3.69Å; F106-F109 HydrophobicContact CD2-CE2 4.46Å; F106-F109 AromaticContact CD2-CZ 3.41Å; F106-F109 HydrophobicContact CD2-CZ 3.41Å; F106-F109 VanDerWaalsContact CD2-CZ 3.41Å; F106-F109 AromaticContact CE1-CE1 3.82Å; F106-F109 HydrophobicContact CE1-CE1 3.82Å; F106-F109 HydrophobicContact CE2-CE1 4.22Å; F106-F109 HydrophobicContact CE2-CZ 4.21Å; F106-F109 HydrophobicContact CG-CD1 4.07Å; F106-F109 AromaticContact CG-CE1 3.12Å; F106-F109 HydrophobicContact CG-CE1 3.12Å; F106-F109 HydrophobicContact CG-CE2 4.05Å; F106-F109 AromaticContact CG-CZ 3.14Å; F106-F109 HydrophobicContact CG-CZ 3.14Å; F106-F109 HydrophobicContact CZ-CE1 4.27Å; F106-K212 PolarHBondContact O-NZ 3.03Å; F106-D213 HydrophobicContact CD2-CB 3.88Å; F106-D213 HydrophobicContact CE2-CB 3.76Å; F106-D213 WeakPolarHBondContact CE2-O 3.25Å; F106-A217 HydrophobicContact CZ-CB 4.37Å; F106-F225 HydrophobicContact CE1-CE2 4.25Å; F106-F225 HydrophobicContact CZ-CD2 4.49Å; F106-F225 AromaticContact CZ-CE2 3.84Å; F106-F225 HydrophobicContact CZ-CE2 3.84Å; F106-I228 HydrophobicContact CD1-CG2 4.09Å; F106-I228 HydrophobicContact CE1-CG2 3.8Å
107	D	52.4	Low	54.6	Low	103 Å²	103	78.1 Å²	78.1	55%	0.551	39%	0.392	S	S	*	.	S	Bend	trans	-110.1	-41.3	167.8	-62.4	-46.9	0	0	0	111.5	P104	P104-D107 WeakPolarHBondContact CB-OD1 3.44Å; P104-D107 WeakPolarHBondContact CG-OD2 3.31Å
108	D	60.3	Low	55.5	Low	105 Å²	105	78 Å²	78	56%	0.561	39%	0.393	S	S	*	.	S	Bend	trans	-104.7	112.2	174.8	-66	-48.8	0	0	0	111.4	R235	D108-R235 IonicContact OD2-CZ 3.64Å; D108-R235 VanDerWaalsContact OD2-CZ 3.23Å; D108-R235 IonicContact OD2-NH1 2.7Å; D108-R235 PolarHBondContact OD2-NH1 2.95Å; D108-R235 IonicContact OD2-NH2 3.94Å; D108-R235 PolarHBondContact OD2-NH2 2.95Å
109	F	65.1	Low	55.9	Low	45 Å²	45	76.2 Å²	76.2	20%	0.197	38%	0.383	C	S	.	.			trans	-110.3	115.7	180	-81.9	-64.9	0	0	0	113.3	F106 N204 I216 Y220	F106-F109 HydrophobicContact CB-CD1 3.98Å; F106-F109 HydrophobicContact CB-CD2 4.04Å; F106-F109 HydrophobicContact CB-CE1 3.32Å; F106-F109 HydrophobicContact CB-CE2 3.39Å; F106-F109 HydrophobicContact CB-CG 4.33Å; F106-F109 HydrophobicContact CB-CZ 3.01Å; F106-F109 AromaticContact CD1-CD1 3.92Å; F106-F109 HydrophobicContact CD1-CD1 3.92Å; F106-F109 AromaticContact CD1-CE1 3.22Å; F106-F109 HydrophobicContact CD1-CE1 3.22Å; F106-F109 AromaticContact CD1-CZ 3.8Å; F106-F109 HydrophobicContact CD1-CZ 3.8Å; F106-F109 AromaticContact CD2-CE1 3.69Å; F106-F109 HydrophobicContact CD2-CE1 3.69Å; F106-F109 HydrophobicContact CD2-CE2 4.46Å; F106-F109 AromaticContact CD2-CZ 3.41Å; F106-F109 HydrophobicContact CD2-CZ 3.41Å; F106-F109 VanDerWaalsContact CD2-CZ 3.41Å; F106-F109 AromaticContact CE1-CE1 3.82Å; F106-F109 HydrophobicContact CE1-CE1 3.82Å; F106-F109 HydrophobicContact CE2-CE1 4.22Å; F106-F109 HydrophobicContact CE2-CZ 4.21Å; F106-F109 HydrophobicContact CG-CD1 4.07Å; F106-F109 AromaticContact CG-CE1 3.12Å; F106-F109 HydrophobicContact CG-CE1 3.12Å; F106-F109 HydrophobicContact CG-CE2 4.05Å; F106-F109 AromaticContact CG-CZ 3.14Å; F106-F109 HydrophobicContact CG-CZ 3.14Å; F106-F109 HydrophobicContact CZ-CE1 4.27Å; F109-N204 HydrophobicContact CD2-CB 4.25Å; F109-N204 HydrophobicContact CE2-CB 4.07Å; F109-I216 HydrophobicContact CD1-CG2 3.86Å; F109-I216 HydrophobicContact CD2-CD1 4.39Å; F109-I216 HydrophobicContact CE1-CB 3.88Å; F109-I216 HydrophobicContact CE1-CD1 4.38Å; F109-I216 HydrophobicContact CE1-CG2 3.17Å; F109-I216 HydrophobicContact CE2-CB 4.45Å; F109-I216 HydrophobicContact CE2-CD1 3.4Å; F109-I216 HydrophobicContact CE2-CG1 4.49Å; F109-I216 HydrophobicContact CE2-CG2 4.11Å; F109-I216 HydrophobicContact CZ-CB 3.57Å; F109-I216 HydrophobicContact CZ-CD1 3.35Å; F109-I216 HydrophobicContact CZ-CG1 4.04Å; F109-I216 HydrophobicContact CZ-CG2 3.3Å; F109-Y220 HydrophobicContact CD1-CE2 4.1Å; F109-Y220 VanDerWaalsContact CD1-OH 3.26Å; F109-Y220 WeakPolarHBondContact CD1-OH 2.96Å; F109-Y220 HydrophobicContact CE1-CE2 4.13Å
110	P	78.1	Confident	56.4	Low	25 Å²	25	71 Å²	71	16%	0.162	37%	0.372	C	S	.	.	P	Polyproline II helix	trans	-70.1	143.1	163.5	30.6	-34.3	0	0	0	110.6	Y220 I228 L266 F267	P110-Y220 WeakPolarHBondContact O-CE1 3.46Å; P110-Y220 PolarHBondContact O-OH 3.47Å; P110-I228 HydrophobicContact CG-CD1 4.09Å; P110-I228 HydrophobicContact CG-CG1 4.2Å; P110-L266 HydrophobicContact CB-CB 4.18Å; P110-L266 HydrophobicContact CB-CD2 3.85Å; P110-L266 WeakPolarHBondContact CB-O 3.29Å; P110-L266 HydrophobicContact CG-CB 4.1Å; P110-L266 HydrophobicContact CG-CD2 3.81Å; P110-L266 HydrophobicContact CG-CG 4.48Å; P110-F267 HydrophobicContact CG-CE1 4.09Å
111	V	79.7	Confident	56.4	Low	51 Å²	51	73.7 Å²	73.7	31%	0.309	38%	0.382	S	S	.	.	P	Polyproline II helix	trans	-71.1	127.3	177.4	179.4	0	0	0	0	109.3	V113 Q116 N198	V111-V113 PolarHBondContact O-N 2.9Å; V111-V113 VanDerWaalsContact O-N 3.16Å; V111-Q116 PolarHBondContact O-NE2 2.99Å; V111-N198 WeakPolarHBondContact CG2-ND2 3.27Å
112	P	81.1	Confident	56.2	Low	0 Å²	0	73.1 Å²	73.1	0%	0	39%	0.392	C	S	.	.	P	Polyproline II helix	trans	-49.6	122.5	-178.5	-20.6	23.7	0	0	0	112	S114 C115 Q116 P200 C219 Y220	P112-S114 WeakPolarHBondContact CB-OG 3.35Å; P112-S114 PolarHBondContact O-N 3.49Å; P112-C115 PolarHBondContact O-N 3.44Å; P112-C115 PolarHBondContact O-SG 3.12Å; P112-Q116 WeakPolarHBondContact O-CG 3.24Å; P112-P200 HydrophobicContact CG-CG 4.02Å; P112-C219 WeakPolarHBondContact CG-O 3.47Å; P112-Y220 HydrophobicContact CB-CD1 3.84Å; P112-Y220 HydrophobicContact CB-CE1 3.97Å; P112-Y220 HydrophobicContact CG-CD1 3.68Å; P112-Y220 HydrophobicContact CG-CE1 3.5Å; P112-Y220 VanDerWaalsContact CG-CE1 3.5Å
113	V	79.9	Confident	56	Low	12 Å²	12	72.1 Å²	72.1	7%	0.073	39%	0.386	C	S	.	.	G	3₁₀ helix	trans	-56.9	-36.5	175.3	-173.5	0	0	0	0	110.1	V111 C115 Q116 F117 E224 K265 L266	V111-V113 PolarHBondContact O-N 2.9Å; V111-V113 VanDerWaalsContact O-N 3.16Å; V113-C115 PolarHBondContact O-N 2.94Å; V113-C115 VanDerWaalsContact O-N 3.12Å; V113-Q116 WeakPolarHBondContact O-CB 3.45Å; V113-Q116 PolarHBondContact O-N 3.46Å; V113-F117 HydrophobicContact CG1-CE2 4.13Å; V113-E224 WeakPolarHBondContact CA-OE1 3.39Å; V113-E224 WeakPolarHBondContact CB-OE1 3.45Å; V113-E224 PolarHBondContact N-OE1 3.23Å; V113-K265 HydrophobicContact CG1-CD 4.04Å; V113-K265 HydrophobicContact CG2-CB 3.8Å; V113-L266 HydrophobicContact CG2-CD2 3.9Å; V113-L266 HydrophobicContact CG2-CG 4.27Å
114	S	75.8	Confident	56.1	Low	12 Å²	12	69.9 Å²	69.9	8%	0.084	39%	0.392	C	S	.	.	G	3₁₀ helix	trans	-55.8	-22.2	173.1	51.6	0	0	0	0	114.8	P112 Q189 E224	P112-S114 WeakPolarHBondContact CB-OG 3.35Å; P112-S114 PolarHBondContact O-N 3.49Å; S114-Q189 PolarHBondContact O-NE2 2.87Å; S114-E224 WeakPolarHBondContact CB-OE2 3.21Å; S114-E224 PolarHBondContact N-OE1 3.08Å; S114-E224 PolarHBondContact OG-OE1 3.12Å; S114-E224 PolarHBondContact OG-OE2 3.34Å
115	C	71.9	Confident	56.4	Low	3 Å²	3	69.8 Å²	69.8	2%	0.02	38%	0.383	C	S	.	.	G	3₁₀ helix	trans	-110.3	14.7	173.9	79.3	0	0	0	0	114.8	P112 V113 L188 Q189 R192	P112-C115 PolarHBondContact O-N 3.44Å; P112-C115 PolarHBondContact O-SG 3.12Å; V113-C115 PolarHBondContact O-N 2.94Å; V113-C115 VanDerWaalsContact O-N 3.12Å; C115-L188 HydrophobicContact CB-CB 3.89Å; C115-L188 HydrophobicContact CB-CD1 4.48Å; C115-Q189 HydrophobicContact CB-CG 4.03Å; C115-R192 PolarHBondContact O-NH1 3.43Å
116	Q	64.7	Low	56.6	Low	89 Å²	89	70.9 Å²	70.9	42%	0.416	39%	0.39	S	S	.	.	T	Hydrogen-bonded Turn	trans	-88.2	-28.1	174.4	-63.1	-179.5	25.2	0	0	113.5	V111 P112 V113	V111-Q116 PolarHBondContact O-NE2 2.99Å; P112-Q116 WeakPolarHBondContact O-CG 3.24Å; V113-Q116 WeakPolarHBondContact O-CB 3.45Å; V113-Q116 PolarHBondContact O-N 3.46Å
117	F	57.8	Low	57	Low	119 Å²	119	72.7 Å²	72.7	52%	0.522	40%	0.398	S	S	.	.			trans	-102.4	108.4	-177.2	-62.6	-83.5	0	0	0	112.7	V113 D119 R125	V113-F117 HydrophobicContact CG1-CE2 4.13Å; F117-D119 VanDerWaalsContact C-N 3.26Å; F117-D119 PolarHBondContact O-N 2.64Å; F117-R125 PolarHBondContact O-NH1 2.87Å; F117-R125 PolarHBondContact O-NH2 3.27Å
118	N	49.1	Very low	58	Low	121 Å²	121	68.1 Å²	68.1	65%	0.647	38%	0.375	S	S	*	.			trans	-68.7	-18.6	178	-74.9	-12.1	0	0	0	114.1	L120	N118-L120 PolarHBondContact O-N 2.89Å
119	D	36.6	Very low	59.1	Low	117 Å²	117	63.2 Å²	63.2	63%	0.626	35%	0.349	S	S	*	.			trans	-73.7	88.6	-172.9	-57.2	-55.7	0	0	0	111.7	F117 F121 R125	F117-D119 VanDerWaalsContact C-N 3.26Å; F117-D119 PolarHBondContact O-N 2.64Å; D119-F121 PolarHBondContact O-N 2.95Å; D119-R125 PolarHBondContact O-NH2 2.85Å
120	L	42.6	Very low	59.4	Low	119 Å²	119	61.5 Å²	61.5	62%	0.623	34%	0.344	S	S	*	.			trans	-64.8	-2.4	-178.3	-144.5	75.3	0	0	0	113.9	N118	N118-L120 PolarHBondContact O-N 2.89Å
121	F	30.1	Very low	58.8	Low	186 Å²	186	65.5 Å²	65.5	82%	0.816	36%	0.36	S	S	*	.	S	Bend	trans	-125.2	138.5	-177.2	-57.5	-90.6	0	0	0	109.3	D119	D119-F121 PolarHBondContact O-N 2.95Å
122	G	28.7	Very low	58.2	Low	76 Å²	76	64 Å²	64	78%	0.784	35%	0.352	S	S	*	.	S	Bend	trans	116	10.9	163.9	0	0	0	0	0	118.5
123	T	31.5	Very low	57.3	Low	111 Å²	111	65 Å²	65	68%	0.681	36%	0.361	S	S	*	.	S	Bend	trans	-152.4	155.2	157.3	32.8	0	0	0	0	109.2	R125	T123-R125 PolarHBondContact O-N 2.8Å
124	S	36.8	Very low	56.5	Low	96 Å²	96	66.2 Å²	66.2	67%	0.671	37%	0.369	S	S	*	.			trans	-68.5	97.9	165.3	-166	0	0	0	0	107.8	V126	S124-V126 VanDerWaalsContact C-N 3.26Å; S124-V126 PolarHBondContact O-N 3.46Å
125	R	52.2	Low	55.7	Low	62 Å²	62	76.5 Å²	76.5	23%	0.234	41%	0.407	C	S	.	.			trans	-80.4	74.9	-174.7	-70.5	-161.3	-178.2	-160.2	6.3	110.3	F117 D119 T123 F127	F117-R125 PolarHBondContact O-NH1 2.87Å; F117-R125 PolarHBondContact O-NH2 3.27Å; D119-R125 PolarHBondContact O-NH2 2.85Å; T123-R125 PolarHBondContact O-N 2.8Å; R125-F127 VanDerWaalsContact C-N 3.25Å; R125-F127 HydrophobicContact CB-CD2 4.09Å; R125-F127 HydrophobicContact CB-CE1 4.32Å; R125-F127 HydrophobicContact CB-CE2 3.64Å; R125-F127 HydrophobicContact CB-CZ 3.79Å; R125-F127 VanDerWaalsContact CD-CZ 3.41Å; R125-F127 HydrophobicContact CG-CZ 4.26Å; R125-F127 WeakPolarHBondContact O-CD2 3.38Å; R125-F127 PolarHBondContact O-N 3.49Å
126	V	58.3	Low	55.2	Low	34 Å²	34	79.4 Å²	79.4	21%	0.206	42%	0.421	C	S	.	.			trans	-70.8	78.8	177.8	-162.7	0	0	0	0	110.3	S124 E131 R258	S124-V126 VanDerWaalsContact C-N 3.26Å; S124-V126 PolarHBondContact O-N 3.46Å; V126-E131 HydrophobicContact CG1-CB 3.33Å; V126-E131 HydrophobicContact CG1-CG 4.12Å; V126-E131 WeakPolarHBondContact CG1-OE2 3.36Å; V126-R258 PolarHBondContact O-NH1 2.8Å
127	F	64.8	Low	55.3	Low	40 Å²	40	76.5 Å²	76.5	18%	0.175	41%	0.408	C	S	.	.			trans	-74.9	-34.5	-175.2	-65.8	-70.7	0	0	0	112.3	R125 E131 L181 V185 T221	R125-F127 VanDerWaalsContact C-N 3.25Å; R125-F127 HydrophobicContact CB-CD2 4.09Å; R125-F127 HydrophobicContact CB-CE1 4.32Å; R125-F127 HydrophobicContact CB-CE2 3.64Å; R125-F127 HydrophobicContact CB-CZ 3.79Å; R125-F127 VanDerWaalsContact CD-CZ 3.41Å; R125-F127 HydrophobicContact CG-CZ 4.26Å; R125-F127 WeakPolarHBondContact O-CD2 3.38Å; R125-F127 PolarHBondContact O-N 3.49Å; F127-E131 PolarHBondContact N-OE1 3.1Å; F127-L181 VanDerWaalsContact C-CD2 3.49Å; F127-L181 HydrophobicContact CB-CD2 3.64Å; F127-L181 HydrophobicContact CB-CG 4.02Å; F127-L181 WeakPolarHBondContact O-CD2 3.31Å; F127-V185 HydrophobicContact CD1-CG2 4.42Å; F127-V185 HydrophobicContact CE1-CG1 3.97Å; F127-V185 HydrophobicContact CE1-CG2 4.39Å; F127-V185 HydrophobicContact CE2-CG1 4.44Å; F127-V185 HydrophobicContact CZ-CB 4.47Å; F127-V185 HydrophobicContact CZ-CG1 3.77Å; F127-T221 HydrophobicContact CB-CG2 4.11Å; F127-T221 HydrophobicContact CD1-CG2 3.9Å; F127-T221 HydrophobicContact CG-CG2 4.47Å
128	G	74	Confident	55.8	Low	7 Å²	7	76.2 Å²	76.2	7%	0.072	41%	0.411	C	S	.	.	S	Bend	trans	-91.2	162.1	-172.8	0	0	0	0	0	114	E131 R258	G128-E131 WeakPolarHBondContact CA-OE1 3.37Å; G128-E131 PolarHBondContact N-OE1 2.99Å; G128-R258 PolarHBondContact O-NH1 3.23Å
129	Y	82.1	Confident	57.2	Low	3 Å²	3	73.9 Å²	73.9	1%	0.012	40%	0.398	C	S	.	.	S	Bend	trans	-79.7	-30.3	170.1	-77.1	-16.9	0	0	0	113.2	E131 S132 A133 P222 A223 D226 R251 H255 I259	Y129-E131 VanDerWaalsContact C-N 3.29Å; Y129-E131 PolarHBondContact O-N 2.85Å; Y129-S132 CarbonylContact O-C 3.57Å; Y129-S132 VanDerWaalsContact O-C 3.27Å; Y129-S132 WeakPolarHBondContact O-CA 3.34Å; Y129-S132 PolarHBondContact O-N 3.31Å; Y129-S132 PolarHBondContact O-OG 3.2Å; Y129-A133 PolarHBondContact O-N 3.4Å; Y129-P222 HydrophobicContact CD1-CB 4.04Å; Y129-P222 HydrophobicContact CD2-CB 3.4Å; Y129-P222 VanDerWaalsContact CD2-CB 3.4Å; Y129-P222 HydrophobicContact CD2-CG 4.26Å; Y129-P222 HydrophobicContact CE1-CB 4Å; Y129-P222 HydrophobicContact CE2-CB 3.34Å; Y129-P222 HydrophobicContact CG-CB 3.78Å; Y129-P222 HydrophobicContact CG-CG 4.35Å; Y129-P222 PolarHBondContact OH-O 3.45Å; Y129-A223 HydrophobicContact CE1-CB 4.11Å; Y129-A223 WeakPolarHBondContact OH-CA 3.32Å; Y129-A223 PolarHBondContact OH-N 2.97Å; Y129-D226 VanDerWaalsContact CE2-OD2 3.23Å; Y129-D226 WeakPolarHBondContact CE2-OD2 3.37Å; Y129-D226 VanDerWaalsContact CZ-OD2 3.31Å; Y129-D226 PolarHBondContact OH-OD2 3.32Å; Y129-R251 HydrophobicContact CE2-CG 4.38Å; Y129-H255 HydrophobicContact CD1-CB 4.05Å; Y129-H255 AromaticContact CD1-CD2 3.31Å; Y129-H255 WeakPolarHBondContact CD1-CD2 3.37Å; Y129-H255 AromaticContact CD1-CG 3.54Å; Y129-H255 AromaticContact CD1-NE2 3.78Å; Y129-H255 HydrophobicContact CE1-CB 3.63Å; Y129-H255 AromaticContact CE1-CD2 3.83Å; Y129-H255 AromaticContact CE1-CG 3.67Å; Y129-H255 AromaticContact CG-CD2 3.78Å; Y129-H255 AromaticContact CG-CE1 3.88Å; Y129-H255 AromaticContact CG-CG 3.88Å; Y129-H255 AromaticContact CG-ND1 3.95Å; Y129-H255 AromaticContact CG-NE2 3.78Å; Y129-H255 PolarHBondContact O-NE2 2.94Å; Y129-H255 VanDerWaalsContact O-NE2 3.17Å; Y129-I259 WeakPolarHBondContact OH-CD1 3.33Å; Y129-I259 WeakPolarHBondContact OH-CG1 3.31Å
130	G	71.9	Confident	59.7	Low	9 Å²	9	70.1 Å²	70.1	9%	0.093	38%	0.379	C	S	.	.	G	3₁₀ helix	trans	-59.4	-37.9	180	0	0	0	0	0	113	S132 A133 I139	G130-S132 PolarHBondContact O-N 2.7Å; G130-A133 PolarHBondContact O-N 3.27Å; G130-I139 WeakPolarHBondContact O-CD1 3.33Å
131	E	65.9	Low	62	Low	108 Å²	108	66.9 Å²	66.9	51%	0.505	37%	0.365	S	S	.	.	G	3₁₀ helix	trans	-65.7	2.9	173.3	-55.7	166.2	-98.2	0	0	114.1	V126 F127 G128 Y129	V126-E131 HydrophobicContact CG1-CB 3.33Å; V126-E131 HydrophobicContact CG1-CG 4.12Å; V126-E131 WeakPolarHBondContact CG1-OE2 3.36Å; F127-E131 PolarHBondContact N-OE1 3.1Å; G128-E131 WeakPolarHBondContact CA-OE1 3.37Å; G128-E131 PolarHBondContact N-OE1 2.99Å; Y129-E131 VanDerWaalsContact C-N 3.29Å; Y129-E131 PolarHBondContact O-N 2.85Å
132	S	66.2	Low	65	Low	19 Å²	19	58.9 Å²	58.9	13%	0.133	33%	0.331	C	S	.	.	G	3₁₀ helix	trans	-148.8	26.1	-177.5	50.9	0	0	0	0	112.1	Y129 G130 H255 R258	Y129-S132 CarbonylContact O-C 3.57Å; Y129-S132 VanDerWaalsContact O-C 3.27Å; Y129-S132 WeakPolarHBondContact O-CA 3.34Å; Y129-S132 PolarHBondContact O-N 3.31Å; Y129-S132 PolarHBondContact O-OG 3.2Å; G130-S132 PolarHBondContact O-N 2.7Å; S132-H255 PolarHBondContact O-NE2 3.14Å; S132-H255 VanDerWaalsContact O-NE2 3.16Å; S132-H255 PolarHBondContact OG-CD2 3.19Å; S132-H255 VanDerWaalsContact OG-CD2 3.28Å; S132-H255 PolarHBondContact OG-NE2 2.75Å; S132-H255 VanDerWaalsContact OG-NE2 3.14Å; S132-R258 PolarHBondContact OG-NH1 2.6Å
133	A	61.6	Low	67.9	Low	22 Å²	22	55.4 Å²	55.4	18%	0.182	30%	0.295	C	S	.	.			trans	-73.2	148.1	166.4	0	0	0	0	0	109.5	Y129 G130 D137 I139	Y129-A133 PolarHBondContact O-N 3.4Å; G130-A133 PolarHBondContact O-N 3.27Å; A133-D137 HydrophobicContact CB-CB 4.06Å; A133-I139 HydrophobicContact CB-CD1 4.2Å; A133-I139 HydrophobicContact CB-CG1 4.06Å
134	P	63.4	Low	70.5	Confident	38 Å²	38	53.3 Å²	53.3	25%	0.247	28%	0.282	C	S	.	.			trans	-62.7	153.7	172.8	-17.9	34	0	0	0	110.5	E136 D137 T252	P134-E136 HydrophobicContact CB-CG 3.78Å; P134-E136 PolarHBondContact O-N 2.98Å; P134-D137 WeakPolarHBondContact CD-OD2 3.45Å; P134-D137 PolarHBondContact O-N 3.31Å; P134-T252 HydrophobicContact CG-CG2 3.77Å
135	Y	60.6	Low	72.9	Confident	227 Å²	227	51.8 Å²	51.8	89%	0.89	27%	0.268	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.4	-19.6	-179.9	-176.3	-96	0	0	0	114.1
136	E	61.1	Low	74.5	Confident	64 Å²	64	51.9 Å²	51.9	30%	0.299	27%	0.272	S	S	.	.	T	Hydrogen-bonded Turn	trans	-79.7	-13.4	174.8	52.8	167.9	-115.5	0	0	114.9	P134 Y338 G339 R342	P134-E136 HydrophobicContact CB-CG 3.78Å; P134-E136 PolarHBondContact O-N 2.98Å; E136-Y338 WeakPolarHBondContact OE1-CB 3.35Å; E136-G339 PolarHBondContact OE2-N 3.42Å; E136-R342 IonicContact OE1-CZ 2.77Å; E136-R342 IonicContact OE1-NH1 2.6Å; E136-R342 PolarHBondContact OE1-NH1 3.17Å; E136-R342 IonicContact OE1-NH2 2.9Å; E136-R342 PolarHBondContact OE1-NH2 2.95Å; E136-R342 IonicContact OE2-CZ 2.73Å; E136-R342 IonicContact OE2-NH1 3.66Å; E136-R342 IonicContact OE2-NH2 2.68Å; E136-R342 PolarHBondContact OE2-NH2 3.48Å
137	D	67	Low	75.8	Confident	29 Å²	29	55.4 Å²	55.4	16%	0.155	30%	0.295	C	S	.	.	S	Bend	trans	-88.5	123.4	179.9	-78.7	13.5	0	0	0	111	A133 P134 I139 R378	A133-D137 HydrophobicContact CB-CB 4.06Å; P134-D137 WeakPolarHBondContact CD-OD2 3.45Å; P134-D137 PolarHBondContact O-N 3.31Å; D137-I139 PolarHBondContact O-N 3.45Å; D137-I139 VanDerWaalsContact O-N 3.08Å; D137-R378 IonicContact OD1-CZ 2.75Å; D137-R378 IonicContact OD1-NH1 2.6Å; D137-R378 PolarHBondContact OD1-NH1 3.2Å; D137-R378 IonicContact OD1-NH2 3.68Å; D137-R378 IonicContact OD2-CZ 3.2Å; D137-R378 IonicContact OD2-NH1 2.8Å; D137-R378 PolarHBondContact OD2-NH1 3.32Å
138	I	66.3	Low	76.8	Confident	113 Å²	113	59.3 Å²	59.3	58%	0.579	32%	0.318	S	S	*	.			trans	-80	94.8	177.2	-48.8	179.8	0	0	0	109.7	T140 Q414	I138-T140 HydrophobicContact CG2-CG2 4.09Å; I138-T140 PolarHBondContact O-N 2.91Å; I138-T140 PolarHBondContact O-OG1 3.17Å; I138-Q414 PolarHBondContact O-OE1 2.85Å; I138-Q414 VanDerWaalsContact O-OE1 3.07Å
139	I	80.5	Confident	77.6	Confident	72 Å²	72	61 Å²	61	37%	0.369	32%	0.323	S	S	.	.			trans	-62.6	110.4	179.9	-48.9	168.8	0	0	0	109.4	G130 A133 D137 P141 V410	G130-I139 WeakPolarHBondContact O-CD1 3.33Å; A133-I139 HydrophobicContact CB-CD1 4.2Å; A133-I139 HydrophobicContact CB-CG1 4.06Å; D137-I139 PolarHBondContact O-N 3.45Å; D137-I139 VanDerWaalsContact O-N 3.08Å; I139-P141 HydrophobicContact CG2-CG 4.49Å; I139-P141 WeakPolarHBondContact O-CD 3.37Å; I139-V410 CarbonylContact C-O 3.27Å; I139-V410 WeakPolarHBondContact CA-O 3.39Å; I139-V410 VanDerWaalsContact CG2-O 3.27Å; I139-V410 WeakPolarHBondContact CG2-O 3.46Å
140	T	88.3	Confident	78	Confident	37 Å²	37	67.3 Å²	67.3	23%	0.227	35%	0.351	C	S	.	.			trans	-124.7	71.5	-178.6	47.6	0	0	0	0	110.2	I138 V410 D411 M412 G413 Q414	I138-T140 HydrophobicContact CG2-CG2 4.09Å; I138-T140 PolarHBondContact O-N 2.91Å; I138-T140 PolarHBondContact O-OG1 3.17Å; T140-V410 CarbonylContact C-O 3.51Å; T140-V410 PolarHBondContact N-O 3.24Å; T140-D411 WeakPolarHBondContact OG1-CA 3.5Å; T140-M412 PolarHBondContact O-N 3.01Å; T140-G413 PolarHBondContact O-N 2.98Å; T140-Q414 HydrophobicContact CG2-CG 4.15Å; T140-Q414 PolarHBondContact OG1-N 2.75Å
141	P	91.2	Very high	79	Confident	52 Å²	52	68.1 Å²	68.1	34%	0.338	35%	0.354	S	S	.	.			trans	-80	128.6	-171.5	33.2	-31.4	0	0	0	110.3	I139 T144	I139-P141 HydrophobicContact CG2-CG 4.49Å; I139-P141 WeakPolarHBondContact O-CD 3.37Å; P141-T144 HydrophobicContact CG-CG2 4.42Å
142	T	92.5	Very high	80.4	Confident	17 Å²	17	66.8 Å²	66.8	10%	0.104	35%	0.348	C	S	.	.	S	Bend	trans	-74.7	-34.9	173.7	46	0	0	0	0	111.4	C408 M412 K416 L469 I470 R471	T142-C408 PolarHBondContact N-O 3.43Å; T142-C408 PolarHBondContact OG1-O 3.1Å; T142-M412 HydrophobicContact CG2-CB 3.87Å; T142-M412 HydrophobicContact CG2-CG 3.61Å; T142-M412 WeakPolarHBondContact OG1-CG 3.4Å; T142-K416 HydrophobicContact CG2-CD 4.21Å; T142-L469 VanDerWaalsContact CB-O 3.29Å; T142-L469 WeakPolarHBondContact CB-O 3.46Å; T142-L469 PolarHBondContact OG1-O 2.83Å; T142-I470 WeakPolarHBondContact CG2-O 3.17Å; T142-R471 WeakPolarHBondContact O-CD 3.46Å; T142-R471 WeakPolarHBondContact O-CG 3.48Å; T142-R471 PolarHBondContact O-NE 3.36Å; T142-R471 PolarHBondContact O-NH1 2.94Å
143	V	90.2	Very high	81.7	Confident	4 Å²	4	70.9 Å²	70.9	2%	0.024	37%	0.365	C	S	.	.			trans	-95.9	133.3	176	-172.2	0	0	0	0	110.8	P180 C408 E409 L469	V143-P180 HydrophobicContact CG1-CB 4.02Å; V143-C408 HydrophobicContact CG2-CB 4.01Å; V143-C408 PolarHBondContact N-O 2.8Å; V143-E409 HydrophobicContact CB-CG 3.92Å; V143-E409 HydrophobicContact CG1-CG 4.48Å; V143-L469 HydrophobicContact CG2-CD2 4.25Å; V143-L469 VanDerWaalsContact CG2-O 3.3Å; V143-L469 WeakPolarHBondContact CG2-O 3.37Å
144	T	85.4	Confident	83.2	Confident	66 Å²	66	70.1 Å²	70.1	41%	0.405	36%	0.357	S	S	.	.			trans	-140.7	163.8	-178.5	66.1	0	0	0	0	110.7	P141 E146 P180 R471	P141-T144 HydrophobicContact CG-CG2 4.42Å; T144-E146 PolarHBondContact O-N 2.82Å; T144-P180 WeakPolarHBondContact O-CD 3.36Å; T144-R471 VanDerWaalsContact N-NH1 3.14Å; T144-R471 VanDerWaalsContact N-NH2 3.14Å; T144-R471 PolarHBondContact O-NH2 2.63Å; T144-R471 PolarHBondContact OG1-NH1 3.2Å; T144-R471 PolarHBondContact OG1-NH2 2.93Å
145	V	86.9	Confident	84.6	Confident	64 Å²	64	68.3 Å²	68.3	39%	0.388	35%	0.346	S	S	.	.			trans	-57.3	127.6	-178.4	-176.6	0	0	0	0	112.1	P180	V145-P180 HydrophobicContact CG2-CG 4.13Å
146	E	85.9	Confident	86.2	Confident	65 Å²	65	61 Å²	61	30%	0.304	32%	0.32	S	S	.	.			trans	-77.1	121.5	166.2	174.6	82.8	-101.4	0	0	109.1	T144 F149 R179 Q183	T144-E146 PolarHBondContact O-N 2.82Å; E146-F149 HydrophobicContact CB-CB 4.4Å; E146-F149 HydrophobicContact CG-CB 4.38Å; E146-F149 WeakPolarHBondContact O-CB 3.39Å; E146-R179 VanDerWaalsContact CB-NH1 3.35Å; E146-R179 IonicContact OE2-CZ 3.54Å; E146-R179 IonicContact OE2-NH1 3.35Å; E146-R179 PolarHBondContact OE2-NH1 2.96Å; E146-R179 IonicContact OE2-NH2 2.72Å; E146-R179 PolarHBondContact OE2-NH2 3.29Å; E146-Q183 PolarHBondContact O-NE2 3.06Å
147	P	85.4	Confident	87.7	Confident	108 Å²	108	60.4 Å²	60.4	70%	0.701	32%	0.315	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.4	-35.9	-178.1	26.1	-33.9	0	0	0	112.8	F149	P147-F149 VanDerWaalsContact C-N 3.26Å; P147-F149 PolarHBondContact O-N 2.95Å
148	N	87.2	Confident	88.9	Confident	122 Å²	122	59.1 Å²	59.1	65%	0.652	31%	0.308	S	S	*	.	T	Hydrogen-bonded Turn	trans	-91.4	44	-176.8	-65.1	-41	0	0	0	112.4	F150	N148-F150 WeakPolarHBondContact O-CD2 3.44Å
149	F	89.3	Confident	90	Very high	42 Å²	42	54.1 Å²	54.1	18%	0.184	28%	0.284	C	S	.	.			trans	-89.9	114	-174.5	172.3	-105.4	0	0	0	112.7	E146 P147 V151 E154 Q183 A186 I187	E146-F149 HydrophobicContact CB-CB 4.4Å; E146-F149 HydrophobicContact CG-CB 4.38Å; E146-F149 WeakPolarHBondContact O-CB 3.39Å; P147-F149 VanDerWaalsContact C-N 3.26Å; P147-F149 PolarHBondContact O-N 2.95Å; F149-V151 HydrophobicContact CE1-CB 3.85Å; F149-V151 HydrophobicContact CE1-CG2 4.34Å; F149-V151 HydrophobicContact CZ-CB 3.77Å; F149-V151 HydrophobicContact CZ-CG2 3.9Å; F149-E154 HydrophobicContact CD2-CG 4.17Å; F149-E154 HydrophobicContact CE2-CG 3.97Å; F149-Q183 HydrophobicContact CD1-CB 4.44Å; F149-Q183 HydrophobicContact CD1-CG 3.83Å; F149-Q183 HydrophobicContact CD2-CB 4.21Å; F149-Q183 HydrophobicContact CD2-CG 4.15Å; F149-Q183 HydrophobicContact CE1-CB 4.1Å; F149-Q183 HydrophobicContact CE1-CG 3.9Å; F149-Q183 HydrophobicContact CE2-CB 3.86Å; F149-Q183 HydrophobicContact CE2-CG 4.22Å; F149-Q183 HydrophobicContact CG-CB 4.48Å; F149-Q183 HydrophobicContact CG-CG 3.94Å; F149-Q183 HydrophobicContact CZ-CB 3.79Å; F149-Q183 HydrophobicContact CZ-CG 4.09Å; F149-Q183 WeakPolarHBondContact CZ-O 3.39Å; F149-A186 HydrophobicContact CE1-CB 4.13Å; F149-A186 HydrophobicContact CZ-CB 4.17Å; F149-I187 HydrophobicContact CE2-CD1 4.04Å; F149-I187 HydrophobicContact CE2-CG1 4.04Å; F149-I187 HydrophobicContact CZ-CD1 4.47Å; F149-I187 HydrophobicContact CZ-CG1 4.04Å
150	F	92.4	Very high	90.4	Very high	136 Å²	136	56 Å²	56	60%	0.596	29%	0.29	S	S	*	.			trans	-115.1	104.1	175.4	-61.7	-83	0	0	0	109.8	N148 E152 H153 E154	N148-F150 WeakPolarHBondContact O-CD2 3.44Å; F150-E152 VanDerWaalsContact C-N 3.33Å; F150-E152 PolarHBondContact O-N 3.32Å; F150-H153 HydrophobicContact CB-CB 4.13Å; F150-H153 PolarHBondContact O-N 3.49Å; F150-H153 VanDerWaalsContact O-N 3.11Å; F150-E154 PolarHBondContact O-N 3.46Å; F150-E154 VanDerWaalsContact O-N 3.11Å
151	V	93	Very high	90.4	Very high	25 Å²	25	56.8 Å²	56.8	15%	0.152	29%	0.288	C	S	.	.	H	α-helix	trans	-64.2	-35.5	-168.5	67.5	0	0	0	0	113	F149 H153 E154 C155 A186 I187 K190	F149-V151 HydrophobicContact CE1-CB 3.85Å; F149-V151 HydrophobicContact CE1-CG2 4.34Å; F149-V151 HydrophobicContact CZ-CB 3.77Å; F149-V151 HydrophobicContact CZ-CG2 3.9Å; V151-H153 PolarHBondContact O-N 3.16Å; V151-E154 PolarHBondContact O-N 3.15Å; V151-C155 WeakPolarHBondContact O-CB 3.37Å; V151-C155 PolarHBondContact O-N 2.91Å; V151-C155 PolarHBondContact O-SG 3.29Å; V151-A186 VanDerWaalsContact CG2-C 3.45Å; V151-A186 HydrophobicContact CG2-CB 3.99Å; V151-A186 WeakPolarHBondContact CG2-O 3.33Å; V151-I187 HydrophobicContact CG2-CG1 4.19Å; V151-K190 HydrophobicContact CG1-CB 4.34Å; V151-K190 HydrophobicContact CG1-CD 4.25Å; V151-K190 HydrophobicContact CG1-CG 4.13Å; V151-K190 HydrophobicContact CG2-CB 3.66Å; V151-K190 HydrophobicContact CG2-CG 4.14Å
152	E	93.8	Very high	90.3	Very high	80 Å²	80	54.3 Å²	54.3	37%	0.374	27%	0.272	S	S	.	.	H	α-helix	trans	-57.2	-48.3	172.7	-70.8	64	-147.7	0	0	111.1	F150 C155 E156 K190	F150-E152 VanDerWaalsContact C-N 3.33Å; F150-E152 PolarHBondContact O-N 3.32Å; E152-C155 PolarHBondContact O-N 2.98Å; E152-E156 PolarHBondContact O-N 3.22Å; E152-K190 WeakPolarHBondContact OE1-CD 3.44Å; E152-K190 WeakPolarHBondContact OE1-CE 3.49Å; E152-K190 IonicContact OE1-NZ 3.74Å; E152-K190 PolarHBondContact OE1-NZ 3.19Å
153	H	93.7	Very high	89.9	Confident	105 Å²	105	58 Å²	58	49%	0.486	30%	0.298	S	S	.	.	H	α-helix	trans	-67.8	-38.1	-178.2	179.4	-144.3	0	0	0	111.4	F150 V151 E156 R157	F150-H153 HydrophobicContact CB-CB 4.13Å; F150-H153 PolarHBondContact O-N 3.49Å; F150-H153 VanDerWaalsContact O-N 3.11Å; V151-H153 PolarHBondContact O-N 3.16Å; H153-E156 PolarHBondContact O-N 3.39Å; H153-R157 WeakPolarHBondContact O-CB 3.36Å; H153-R157 VanDerWaalsContact O-CG 3.24Å; H153-R157 WeakPolarHBondContact O-CG 3.27Å; H153-R157 PolarHBondContact O-N 3.41Å
154	E	93.1	Very high	89.6	Confident	6 Å²	6	64.8 Å²	64.8	3%	0.028	32%	0.323	C	S	.	.	H	α-helix	trans	-67.8	-36.7	174.4	-60.3	-67.5	-156.1	0	0	112.1	F149 F150 V151 R157 L158 V175 R179 I187	F149-E154 HydrophobicContact CD2-CG 4.17Å; F149-E154 HydrophobicContact CE2-CG 3.97Å; F150-E154 PolarHBondContact O-N 3.46Å; F150-E154 VanDerWaalsContact O-N 3.11Å; V151-E154 PolarHBondContact O-N 3.15Å; E154-R157 WeakPolarHBondContact O-CB 3.48Å; E154-R157 PolarHBondContact O-N 3.45Å; E154-R157 IonicContact OE1-NH1 3.33Å; E154-R157 PolarHBondContact OE1-NH1 3.32Å; E154-R157 VanDerWaalsContact OE2-CD 3.32Å; E154-R157 WeakPolarHBondContact OE2-CD 3.45Å; E154-R157 IonicContact OE2-CZ 2.77Å; E154-R157 IonicContact OE2-NE 3.05Å; E154-R157 IonicContact OE2-NH1 3.33Å; E154-R157 PolarHBondContact OE2-NH1 3.17Å; E154-L158 WeakPolarHBondContact O-CG 3.25Å; E154-L158 PolarHBondContact O-N 2.98Å; E154-V175 HydrophobicContact CB-CG1 3.95Å; E154-V175 HydrophobicContact CG-CG1 4.45Å; E154-R179 IonicContact OE1-CZ 3.18Å; E154-R179 IonicContact OE1-NE 2.65Å; E154-R179 PolarHBondContact OE1-NE 3.4Å; E154-R179 IonicContact OE1-NH2 2.69Å; E154-R179 PolarHBondContact OE1-NH2 3.07Å; E154-I187 HydrophobicContact CB-CD1 3.98Å; E154-I187 HydrophobicContact CB-CG1 4.05Å; E154-I187 HydrophobicContact CG-CD1 4.49Å
155	C	93.6	Very high	89.2	Confident	0 Å²	0	69.6 Å²	69.6	0%	0	35%	0.345	C	S	.	.	H	α-helix	trans	-66.6	-44.2	173.3	-68.6	0	0	0	0	112.2	V151 E152 R157 L158 G159 I187 Y191 M194 Y195	V151-C155 WeakPolarHBondContact O-CB 3.37Å; V151-C155 PolarHBondContact O-N 2.91Å; V151-C155 PolarHBondContact O-SG 3.29Å; E152-C155 PolarHBondContact O-N 2.98Å; C155-R157 VanDerWaalsContact C-N 3.3Å; C155-R157 PolarHBondContact O-N 2.84Å; C155-L158 PolarHBondContact O-N 3.22Å; C155-G159 PolarHBondContact O-N 3.46Å; C155-I187 PolarHBondContact SG-O 3.32Å; C155-Y191 HydrophobicContact CB-CD2 4.46Å; C155-Y191 PolarHBondContact SG-N 2.95Å; C155-Y191 VanDerWaalsContact SG-N 3.45Å; C155-M194 HydrophobicContact CB-SD 3.7Å; C155-Y195 HydrophobicContact CB-CE2 4.47Å
156	E	93.5	Very high	89	Confident	74 Å²	74	71.2 Å²	71.2	35%	0.346	36%	0.358	S	S	.	.	H	α-helix	trans	-59.6	-40.6	170.7	-82.5	-163.1	-150.6	0	0	112.2	E152 H153 K160 M194 Y195	E152-E156 PolarHBondContact O-N 3.22Å; H153-E156 PolarHBondContact O-N 3.39Å; E156-K160 WeakPolarHBondContact O-CB 3.39Å; E156-K160 WeakPolarHBondContact O-CD 3.5Å; E156-K160 VanDerWaalsContact O-CG 3.26Å; E156-K160 WeakPolarHBondContact O-CG 3.08Å; E156-K160 PolarHBondContact O-N 3.04Å; E156-K160 IonicContact OE2-NZ 3.19Å; E156-K160 PolarHBondContact OE2-NZ 3.34Å; E156-M194 HydrophobicContact CG-CE 4.04Å; E156-Y195 WeakPolarHBondContact CA-OH 3.33Å
157	R	92.1	Very high	89	Confident	52 Å²	52	68.8 Å²	68.8	20%	0.196	35%	0.348	C	S	.	.	H	α-helix	trans	-58.2	-57.6	176.4	-79.9	170.8	74.5	-167.9	11.9	108.8	H153 E154 C155 G159 K160 R161 V175	H153-R157 WeakPolarHBondContact O-CB 3.36Å; H153-R157 VanDerWaalsContact O-CG 3.24Å; H153-R157 WeakPolarHBondContact O-CG 3.27Å; H153-R157 PolarHBondContact O-N 3.41Å; E154-R157 WeakPolarHBondContact O-CB 3.48Å; E154-R157 PolarHBondContact O-N 3.45Å; E154-R157 IonicContact OE1-NH1 3.33Å; E154-R157 PolarHBondContact OE1-NH1 3.32Å; E154-R157 VanDerWaalsContact OE2-CD 3.32Å; E154-R157 WeakPolarHBondContact OE2-CD 3.45Å; E154-R157 IonicContact OE2-CZ 2.77Å; E154-R157 IonicContact OE2-NE 3.05Å; E154-R157 IonicContact OE2-NH1 3.33Å; E154-R157 PolarHBondContact OE2-NH1 3.17Å; C155-R157 VanDerWaalsContact C-N 3.3Å; C155-R157 PolarHBondContact O-N 2.84Å; R157-G159 PolarHBondContact O-N 2.84Å; R157-K160 PolarHBondContact O-N 2.66Å; R157-R161 VanDerWaalsContact CA-NH1 3.32Å; R157-R161 WeakPolarHBondContact O-CD 3.35Å; R157-R161 PolarHBondContact O-NH1 2.75Å; R157-V175 HydrophobicContact CB-CG2 3.92Å
158	L	92.7	Very high	89.1	Confident	1 Å²	1	65.8 Å²	65.8	1%	0.005	33%	0.326	C	S	.	.	H	α-helix	trans	-57.6	-48.2	178.3	-71.5	166.1	0	0	0	112.8	E154 C155 K160 R161 L162 V172 V175 M176 I187 Y191 L199 F203	E154-L158 WeakPolarHBondContact O-CG 3.25Å; E154-L158 PolarHBondContact O-N 2.98Å; C155-L158 PolarHBondContact O-N 3.22Å; L158-K160 PolarHBondContact O-N 3.3Å; L158-R161 PolarHBondContact O-N 2.92Å; L158-R161 VanDerWaalsContact O-N 3.08Å; L158-L162 HydrophobicContact CB-CD1 4.2Å; L158-L162 HydrophobicContact CD2-CD1 4.5Å; L158-L162 WeakPolarHBondContact O-CB 3.48Å; L158-L162 WeakPolarHBondContact O-CG 3.42Å; L158-L162 PolarHBondContact O-N 3.19Å; L158-V172 HydrophobicContact CD2-CB 4.48Å; L158-V172 HydrophobicContact CD2-CG1 3.97Å; L158-V172 HydrophobicContact CD2-CG2 4.38Å; L158-V175 HydrophobicContact CD1-CG1 3.85Å; L158-V175 HydrophobicContact CD2-CB 4.15Å; L158-V175 HydrophobicContact CD2-CG1 4.22Å; L158-V175 HydrophobicContact CG-CB 4.24Å; L158-V175 HydrophobicContact CG-CG1 3.87Å; L158-V175 HydrophobicContact CG-CG2 4.44Å; L158-M176 HydrophobicContact CD1-SD 4.29Å; L158-M176 HydrophobicContact CD2-CG 4.48Å; L158-I187 HydrophobicContact CD1-CG2 3.53Å; L158-Y191 HydrophobicContact CB-CD2 4.33Å; L158-Y191 HydrophobicContact CB-CE2 4.1Å; L158-L199 HydrophobicContact CD1-CD2 3.94Å; L158-F203 HydrophobicContact CD2-CZ 4.45Å
159	G	88.8	Confident	89.2	Confident	8 Å²	8	62.4 Å²	62.4	8%	0.082	31%	0.307	C	S	.	.	H	α-helix	trans	-54.5	-49.3	-179.3	0	0	0	0	0	112.7	C155 R157 R161 L162 C163	C155-G159 PolarHBondContact O-N 3.46Å; R157-G159 PolarHBondContact O-N 2.84Å; G159-R161 PolarHBondContact O-N 3.09Å; G159-R161 VanDerWaalsContact O-N 3.13Å; G159-L162 PolarHBondContact O-N 3.24Å; G159-C163 WeakPolarHBondContact O-CB 3.42Å; G159-C163 PolarHBondContact O-N 3.4Å; G159-C163 VanDerWaalsContact O-N 3.09Å; G159-C163 PolarHBondContact O-SG 3.29Å
160	K	89	Confident	89.2	Confident	112 Å²	112	68.8 Å²	68.8	49%	0.487	33%	0.329	S	S	.	.	H	α-helix	trans	-66.5	-9.2	179.8	-70.4	166.3	177.2	169.6	0	114.8	E156 R157 L158 R164	E156-K160 WeakPolarHBondContact O-CB 3.39Å; E156-K160 WeakPolarHBondContact O-CD 3.5Å; E156-K160 VanDerWaalsContact O-CG 3.26Å; E156-K160 WeakPolarHBondContact O-CG 3.08Å; E156-K160 PolarHBondContact O-N 3.04Å; E156-K160 IonicContact OE2-NZ 3.19Å; E156-K160 PolarHBondContact OE2-NZ 3.34Å; R157-K160 PolarHBondContact O-N 2.66Å; L158-K160 PolarHBondContact O-N 3.3Å; K160-R164 PolarHBondContact O-NE 2.97Å
161	R	88.4	Confident	89.1	Confident	53 Å²	53	66.2 Å²	66.2	20%	0.2	32%	0.318	C	S	.	.	H	α-helix	trans	-105.1	-44.5	173.1	-72.7	81	-174.9	153.5	-1.9	111.4	R157 L158 G159 C163 R164 D168 K171 V172	R157-R161 VanDerWaalsContact CA-NH1 3.32Å; R157-R161 WeakPolarHBondContact O-CD 3.35Å; R157-R161 PolarHBondContact O-NH1 2.75Å; L158-R161 PolarHBondContact O-N 2.92Å; L158-R161 VanDerWaalsContact O-N 3.08Å; G159-R161 PolarHBondContact O-N 3.09Å; G159-R161 VanDerWaalsContact O-N 3.13Å; R161-C163 VanDerWaalsContact C-N 3.29Å; R161-C163 PolarHBondContact O-N 2.91Å; R161-R164 WeakPolarHBondContact O-CB 3.45Å; R161-R164 PolarHBondContact O-N 3.49Å; R161-D168 HydrophobicContact CB-CB 4.45Å; R161-D168 HydrophobicContact CG-CB 3.79Å; R161-K171 HydrophobicContact CG-CB 4.18Å; R161-V172 HydrophobicContact CB-CG2 4.49Å
162	L	89	Confident	89.1	Confident	0 Å²	0	65 Å²	65	0%	0	31%	0.311	C	S	.	.	H	α-helix	trans	-74.5	-13.5	-176.9	-64.9	171.3	0	0	0	114.1	L158 G159 V167 V172 L199 K202 F203	L158-L162 HydrophobicContact CB-CD1 4.2Å; L158-L162 HydrophobicContact CD2-CD1 4.5Å; L158-L162 WeakPolarHBondContact O-CB 3.48Å; L158-L162 WeakPolarHBondContact O-CG 3.42Å; L158-L162 PolarHBondContact O-N 3.19Å; G159-L162 PolarHBondContact O-N 3.24Å; L162-V167 HydrophobicContact CD2-CG1 4.01Å; L162-V167 HydrophobicContact CD2-CG2 4.45Å; L162-V172 HydrophobicContact CD2-CG2 4.42Å; L162-L199 HydrophobicContact CD1-CD1 3.53Å; L162-K202 HydrophobicContact CB-CG 4.23Å; L162-K202 HydrophobicContact CD1-CG 4.16Å; L162-K202 WeakPolarHBondContact O-CE 3.36Å; L162-K202 PolarHBondContact O-NZ 3.23Å; L162-F203 HydrophobicContact CD1-CD1 4.19Å; L162-F203 HydrophobicContact CD1-CE1 3.78Å; L162-F203 HydrophobicContact CD2-CD1 3.95Å; L162-F203 HydrophobicContact CD2-CE1 4.01Å; L162-F203 HydrophobicContact CG-CE1 4.49Å
163	C	85	Confident	89	Confident	95 Å²	95	61.5 Å²	61.5	64%	0.642	30%	0.295	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.2	-21.7	170.8	66	0	0	0	0	113.9	G159 R161	G159-C163 WeakPolarHBondContact O-CB 3.42Å; G159-C163 PolarHBondContact O-N 3.4Å; G159-C163 VanDerWaalsContact O-N 3.09Å; G159-C163 PolarHBondContact O-SG 3.29Å; R161-C163 VanDerWaalsContact C-N 3.29Å; R161-C163 PolarHBondContact O-N 2.91Å
164	R	82.7	Confident	88.8	Confident	146 Å²	146	61 Å²	61	55%	0.551	29%	0.292	S	S	*	.	S	Bend	trans	-72.7	164.9	-173.8	-61.8	179.5	177	-137	-11.9	112	K160 R161 S166 K206	K160-R164 PolarHBondContact O-NE 2.97Å; R161-R164 WeakPolarHBondContact O-CB 3.45Å; R161-R164 PolarHBondContact O-N 3.49Å; R164-S166 WeakPolarHBondContact CB-O 3.13Å; R164-K206 WeakPolarHBondContact O-CE 3.44Å; R164-K206 PolarHBondContact O-NZ 2.73Å
165	I	77.9	Confident	88.7	Confident	168 Å²	168	60.7 Å²	60.7	86%	0.862	29%	0.291	S	S	*	.	S	Bend	trans	-64	-64.3	172.7	-64.3	170.4	0	0	0	108.8	K206	I165-K206 PolarHBondContact O-NZ 3.15Å
166	S	81.9	Confident	88.7	Confident	97 Å²	97	60.7 Å²	60.7	68%	0.678	29%	0.291	S	S	*	.	S	Bend	trans	-88.8	138.9	167	176.8	0	0	0	0	111.1	R164	R164-S166 WeakPolarHBondContact CB-O 3.13Å
167	V	87.3	Confident	88.4	Confident	14 Å²	14	57.2 Å²	57.2	9%	0.085	28%	0.275	C	S	.	.			trans	-92.6	137.8	-177.5	-179	0	0	0	0	110.2	L162 E169 V172 K206 L207	L162-V167 HydrophobicContact CD2-CG1 4.01Å; L162-V167 HydrophobicContact CD2-CG2 4.45Å; V167-E169 VanDerWaalsContact C-N 3.3Å; V167-E169 HydrophobicContact CB-CG 4.38Å; V167-E169 HydrophobicContact CG1-CG 4.35Å; V167-E169 PolarHBondContact O-N 3.25Å; V167-V172 HydrophobicContact CG1-CG2 3.89Å; V167-K206 HydrophobicContact CG2-CB 4.17Å; V167-K206 HydrophobicContact CG2-CD 3.9Å; V167-K206 HydrophobicContact CG2-CG 4.47Å; V167-L207 HydrophobicContact CB-CD2 4.15Å; V167-L207 HydrophobicContact CG1-CD2 4.21Å; V167-L207 HydrophobicContact CG2-CD2 4.32Å
168	D	87.2	Confident	88	Confident	45 Å²	45	56.9 Å²	56.9	24%	0.241	28%	0.275	C	S	.	.			trans	-82.9	79.5	170.2	-175	-23	0	0	0	109.5	R161 R170 K171 V172	R161-D168 HydrophobicContact CB-CB 4.45Å; R161-D168 HydrophobicContact CG-CB 3.79Å; D168-R170 VanDerWaalsContact C-N 3.27Å; D168-R170 PolarHBondContact O-N 3.06Å; D168-K171 HydrophobicContact CB-CB 4.41Å; D168-K171 PolarHBondContact O-N 3.23Å; D168-K171 WeakPolarHBondContact OD1-CG 3.4Å; D168-K171 PolarHBondContact OD1-N 2.8Å; D168-K171 VanDerWaalsContact OD1-N 3.16Å; D168-K171 IonicContact OD1-NZ 2.58Å; D168-K171 WeakPolarHBondContact OD2-CD 3.43Å; D168-K171 WeakPolarHBondContact OD2-CE 3.45Å; D168-K171 IonicContact OD2-NZ 2.6Å; D168-K171 PolarHBondContact OD2-NZ 3.1Å; D168-V172 PolarHBondContact O-N 2.6Å; D168-V172 VanDerWaalsContact O-N 3.14Å
169	E	89.3	Confident	87.8	Confident	52 Å²	52	57.5 Å²	57.5	24%	0.243	28%	0.278	C	S	.	.	H	α-helix	trans	-58.9	-36.8	-173.2	-61.3	171.1	96.6	0	0	112.3	V167 K171 V172 I173 L207 F211 N461	V167-E169 VanDerWaalsContact C-N 3.3Å; V167-E169 HydrophobicContact CB-CG 4.38Å; V167-E169 HydrophobicContact CG1-CG 4.35Å; V167-E169 PolarHBondContact O-N 3.25Å; E169-K171 VanDerWaalsContact C-N 3.3Å; E169-K171 PolarHBondContact O-N 2.93Å; E169-V172 CarbonylContact O-C 3.32Å; E169-V172 WeakPolarHBondContact O-CA 3.46Å; E169-V172 WeakPolarHBondContact O-CB 3.3Å; E169-V172 PolarHBondContact O-N 3.28Å; E169-I173 WeakPolarHBondContact O-CG1 3.42Å; E169-I173 PolarHBondContact O-N 3.3Å; E169-L207 HydrophobicContact CG-CD2 3.97Å; E169-F211 HydrophobicContact CB-CE1 3.64Å; E169-F211 HydrophobicContact CB-CZ 3.98Å; E169-F211 HydrophobicContact CG-CD1 4.34Å; E169-F211 HydrophobicContact CG-CE1 3.7Å; E169-F211 VanDerWaalsContact OE1-CD1 3.24Å; E169-F211 WeakPolarHBondContact OE1-CD1 3.49Å; E169-F211 WeakPolarHBondContact OE1-CE1 3.44Å; E169-N461 PolarHBondContact OE1-ND2 3.29Å; E169-N461 PolarHBondContact OE2-ND2 3.36Å
170	R	89.2	Confident	87.9	Confident	176 Å²	176	57.4 Å²	57.4	66%	0.664	28%	0.275	S	S	*	.	H	α-helix	trans	-58.9	-40.8	174.6	-62.6	-175.9	-172.8	177	4.6	111.6	D168 I173 Q174	D168-R170 VanDerWaalsContact C-N 3.27Å; D168-R170 PolarHBondContact O-N 3.06Å; R170-I173 PolarHBondContact O-N 3.42Å; R170-Q174 WeakPolarHBondContact O-CG 3.32Å; R170-Q174 PolarHBondContact O-N 2.8Å
171	K	89.4	Confident	88	Confident	81 Å²	81	52.2 Å²	52.2	35%	0.352	25%	0.253	S	S	.	.	H	α-helix	trans	-75.7	-21.1	175	-68.9	-171.7	-171.3	69.4	0	113.2	R161 D168 E169 V175	R161-K171 HydrophobicContact CG-CB 4.18Å; D168-K171 HydrophobicContact CB-CB 4.41Å; D168-K171 PolarHBondContact O-N 3.23Å; D168-K171 WeakPolarHBondContact OD1-CG 3.4Å; D168-K171 PolarHBondContact OD1-N 2.8Å; D168-K171 VanDerWaalsContact OD1-N 3.16Å; D168-K171 IonicContact OD1-NZ 2.58Å; D168-K171 WeakPolarHBondContact OD2-CD 3.43Å; D168-K171 WeakPolarHBondContact OD2-CE 3.45Å; D168-K171 IonicContact OD2-NZ 2.6Å; D168-K171 PolarHBondContact OD2-NZ 3.1Å; E169-K171 VanDerWaalsContact C-N 3.3Å; E169-K171 PolarHBondContact O-N 2.93Å; K171-V175 WeakPolarHBondContact O-CG2 3.37Å
172	V	92.9	Very high	88	Confident	1 Å²	1	51.8 Å²	51.8	1%	0.006	26%	0.256	C	S	.	.	H	α-helix	trans	-72.3	-43.9	168.4	-180	0	0	0	0	110.7	L158 R161 L162 V167 D168 E169 Q174 V175 M176 F203 L215	L158-V172 HydrophobicContact CD2-CB 4.48Å; L158-V172 HydrophobicContact CD2-CG1 3.97Å; L158-V172 HydrophobicContact CD2-CG2 4.38Å; R161-V172 HydrophobicContact CB-CG2 4.49Å; L162-V172 HydrophobicContact CD2-CG2 4.42Å; V167-V172 HydrophobicContact CG1-CG2 3.89Å; D168-V172 PolarHBondContact O-N 2.6Å; D168-V172 VanDerWaalsContact O-N 3.14Å; E169-V172 CarbonylContact O-C 3.32Å; E169-V172 WeakPolarHBondContact O-CA 3.46Å; E169-V172 WeakPolarHBondContact O-CB 3.3Å; E169-V172 PolarHBondContact O-N 3.28Å; V172-Q174 VanDerWaalsContact C-N 3.3Å; V172-Q174 PolarHBondContact O-N 3.03Å; V172-V175 PolarHBondContact O-N 3.29Å; V172-V175 VanDerWaalsContact O-N 3.13Å; V172-M176 HydrophobicContact CG1-CG 4.45Å; V172-M176 PolarHBondContact O-N 3.17Å; V172-F203 HydrophobicContact CG1-CE1 3.72Å; V172-F203 HydrophobicContact CG1-CZ 4.13Å; V172-L215 HydrophobicContact CG1-CD1 3.72Å; V172-L215 HydrophobicContact CG1-CD2 3.84Å; V172-L215 HydrophobicContact CG1-CG 4.46Å
173	I	92.6	Very high	88.1	Confident	6 Å²	6	52.4 Å²	52.4	3%	0.031	26%	0.259	C	S	.	.	H	α-helix	trans	-57.5	-42.5	173.2	-67.7	162.1	0	0	0	111.1	E169 R170 V175 G177 F211 N461 M465 K468	E169-I173 WeakPolarHBondContact O-CG1 3.42Å; E169-I173 PolarHBondContact O-N 3.3Å; R170-I173 PolarHBondContact O-N 3.42Å; I173-V175 VanDerWaalsContact C-N 3.28Å; I173-V175 PolarHBondContact O-N 3.27Å; I173-G177 WeakPolarHBondContact O-CA 3.19Å; I173-G177 PolarHBondContact O-N 2.93Å; I173-F211 HydrophobicContact CD1-CE2 3.77Å; I173-F211 HydrophobicContact CD1-CZ 4.03Å; I173-F211 HydrophobicContact CG1-CE2 3.55Å; I173-F211 HydrophobicContact CG1-CZ 3.77Å; I173-N461 HydrophobicContact CD1-CB 4.21Å; I173-M465 HydrophobicContact CB-CE 4.35Å; I173-M465 HydrophobicContact CB-SD 4.4Å; I173-M465 HydrophobicContact CG1-CB 4.44Å; I173-M465 HydrophobicContact CG1-CE 3.89Å; I173-M465 HydrophobicContact CG1-SD 4.27Å; I173-M465 HydrophobicContact CG2-SD 4.13Å; I173-K468 HydrophobicContact CG2-CG 4.05Å
174	Q	89.5	Confident	88.5	Confident	93 Å²	93	48 Å²	48	44%	0.435	23%	0.229	S	C	.	.	H	α-helix	trans	-57	-39.2	176.1	-77.5	177	-6.5	0	0	113.4	R170 V172 H178	R170-Q174 WeakPolarHBondContact O-CG 3.32Å; R170-Q174 PolarHBondContact O-N 2.8Å; V172-Q174 VanDerWaalsContact C-N 3.3Å; V172-Q174 PolarHBondContact O-N 3.03Å; Q174-H178 PolarHBondContact O-ND1 2.98Å
175	V	91.2	Very high	88.9	Confident	1 Å²	1	41.2 Å²	41.2	1%	0.006	20%	0.204	C	C	.	.	H	α-helix	trans	-79	-47.2	-179.8	179.2	0	0	0	0	111.5	E154 R157 L158 K171 V172 I173 R179 I187	E154-V175 HydrophobicContact CB-CG1 3.95Å; E154-V175 HydrophobicContact CG-CG1 4.45Å; R157-V175 HydrophobicContact CB-CG2 3.92Å; L158-V175 HydrophobicContact CD1-CG1 3.85Å; L158-V175 HydrophobicContact CD2-CB 4.15Å; L158-V175 HydrophobicContact CD2-CG1 4.22Å; L158-V175 HydrophobicContact CG-CB 4.24Å; L158-V175 HydrophobicContact CG-CG1 3.87Å; L158-V175 HydrophobicContact CG-CG2 4.44Å; K171-V175 WeakPolarHBondContact O-CG2 3.37Å; V172-V175 PolarHBondContact O-N 3.29Å; V172-V175 VanDerWaalsContact O-N 3.13Å; I173-V175 VanDerWaalsContact C-N 3.28Å; I173-V175 PolarHBondContact O-N 3.27Å; V175-R179 WeakPolarHBondContact O-CG 3.36Å; V175-I187 HydrophobicContact CG1-CD1 4.04Å
176	M	92.6	Very high	89.6	Confident	0 Å²	0	34.4 Å²	34.4	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-84.5	-37.7	-171.8	-65	-64.3	-68.6	0	0	113.5	L158 V172 H178 R184 L199 F203 L215 L218 M465	L158-M176 HydrophobicContact CD1-SD 4.29Å; L158-M176 HydrophobicContact CD2-CG 4.48Å; V172-M176 HydrophobicContact CG1-CG 4.45Å; V172-M176 PolarHBondContact O-N 3.17Å; M176-H178 VanDerWaalsContact C-N 3.31Å; M176-H178 PolarHBondContact O-N 2.82Å; M176-R184 HydrophobicContact CE-CG 4.44Å; M176-L199 HydrophobicContact SD-CD2 4.38Å; M176-F203 HydrophobicContact CE-CE2 4.35Å; M176-F203 HydrophobicContact CG-CZ 4.23Å; M176-F203 HydrophobicContact SD-CZ 4.49Å; M176-L215 HydrophobicContact CB-CD2 3.8Å; M176-L215 HydrophobicContact CG-CD2 3.63Å; M176-L218 HydrophobicContact CE-CB 4.48Å; M176-M465 HydrophobicContact CB-CE 3.96Å
177	G	88.5	Confident	90.1	Very high	0 Å²	0	29.8 Å²	29.8	0%	0	14%	0.14	C	C	.	.	T	Hydrogen-bonded Turn	trans	-77	-4.9	-168.8	0	0	0	0	0	116.4	I173 M465 K468	I173-G177 WeakPolarHBondContact O-CA 3.19Å; I173-G177 PolarHBondContact O-N 2.93Å; G177-M465 WeakPolarHBondContact CA-SD 3.19Å; G177-K468 CarbonylContact O-C 3.58Å; G177-K468 WeakPolarHBondContact O-CB 3.27Å
178	H	82.1	Confident	90.3	Very high	46 Å²	46	29.3 Å²	29.3	21%	0.213	14%	0.137	C	C	.	.	T	Hydrogen-bonded Turn	trans	-118	2.7	-179.9	-52.6	98.8	0	0	0	113.6	Q174 M176 K468	Q174-H178 PolarHBondContact O-ND1 2.98Å; M176-H178 VanDerWaalsContact C-N 3.31Å; M176-H178 PolarHBondContact O-N 2.82Å; H178-K468 VanDerWaalsContact NE2-CD 3.31Å; H178-K468 WeakPolarHBondContact NE2-CD 3.43Å; H178-K468 WeakPolarHBondContact NE2-CE 3.31Å; H178-K468 PolarHBondContact NE2-NZ 3.23Å
179	R	89.1	Confident	90.5	Very high	14 Å²	14	28.1 Å²	28.1	5%	0.053	13%	0.13	C	C	.	.			trans	-108.3	128.4	-173.2	-59.7	-70.9	168.1	-106.8	10.6	109.4	E146 E154 V175 Q183 R184 I187	E146-R179 VanDerWaalsContact CB-NH1 3.35Å; E146-R179 IonicContact OE2-CZ 3.54Å; E146-R179 IonicContact OE2-NH1 3.35Å; E146-R179 PolarHBondContact OE2-NH1 2.96Å; E146-R179 IonicContact OE2-NH2 2.72Å; E146-R179 PolarHBondContact OE2-NH2 3.29Å; E154-R179 IonicContact OE1-CZ 3.18Å; E154-R179 IonicContact OE1-NE 2.65Å; E154-R179 PolarHBondContact OE1-NE 3.4Å; E154-R179 IonicContact OE1-NH2 2.69Å; E154-R179 PolarHBondContact OE1-NH2 3.07Å; V175-R179 WeakPolarHBondContact O-CG 3.36Å; R179-Q183 HydrophobicContact CB-CB 4.02Å; R179-R184 HydrophobicContact CB-CG 4.02Å; R179-R184 WeakPolarHBondContact O-CG 3.4Å; R179-R184 PolarHBondContact O-NH1 3.21Å; R179-I187 HydrophobicContact CG-CD1 4.41Å
180	P	91	Very high	90.7	Very high	5 Å²	5	28.7 Å²	28.7	3%	0.032	13%	0.132	C	C	.	.			trans	-69.3	166.6	171.8	32.2	-36.8	0	0	0	110.7	V143 T144 V145 V182 Q183 R184 E409	V143-P180 HydrophobicContact CG1-CB 4.02Å; T144-P180 WeakPolarHBondContact O-CD 3.36Å; V145-P180 HydrophobicContact CG2-CG 4.13Å; P180-V182 VanDerWaalsContact C-N 3.29Å; P180-V182 HydrophobicContact CG-CG1 4.14Å; P180-V182 PolarHBondContact O-N 2.89Å; P180-Q183 HydrophobicContact CG-CB 4.39Å; P180-Q183 HydrophobicContact CG-CG 4.25Å; P180-Q183 WeakPolarHBondContact O-CA 3.17Å; P180-Q183 PolarHBondContact O-N 3.23Å; P180-R184 PolarHBondContact O-N 3.5Å; P180-E409 WeakPolarHBondContact CA-OE2 3.5Å; P180-E409 HydrophobicContact CB-CG 4.48Å; P180-E409 WeakPolarHBondContact CB-OE2 3.41Å
181	L	90.6	Very high	90.9	Very high	3 Å²	3	20.8 Å²	20.8	2%	0.016	10%	0.102	C	C	.	.	H	α-helix	trans	-50.7	-43.9	-174.7	-179.6	61.1	0	0	0	113.4	F127 Q183 R184 V185 Y220 T221 P222 E409	F127-L181 VanDerWaalsContact C-CD2 3.49Å; F127-L181 HydrophobicContact CB-CD2 3.64Å; F127-L181 HydrophobicContact CB-CG 4.02Å; F127-L181 WeakPolarHBondContact O-CD2 3.31Å; L181-Q183 VanDerWaalsContact C-N 3.28Å; L181-Q183 PolarHBondContact O-N 2.81Å; L181-R184 CarbonylContact O-C 3.42Å; L181-R184 PolarHBondContact O-N 3.03Å; L181-R184 VanDerWaalsContact O-N 3.12Å; L181-V185 HydrophobicContact CD1-CG2 4.02Å; L181-V185 HydrophobicContact CG-CG2 4.37Å; L181-V185 WeakPolarHBondContact O-CB 3.48Å; L181-V185 WeakPolarHBondContact O-CG2 3.4Å; L181-V185 PolarHBondContact O-N 2.77Å; L181-Y220 WeakPolarHBondContact CD1-O 3.47Å; L181-T221 HydrophobicContact CD1-CG2 4.17Å; L181-T221 HydrophobicContact CD2-CG2 4.05Å; L181-T221 HydrophobicContact CG-CG2 4.42Å; L181-P222 VanDerWaalsContact CD2-CD 3.43Å; L181-P222 HydrophobicContact CD2-CG 4.41Å; L181-E409 WeakPolarHBondContact CB-OE2 3.36Å; L181-E409 VanDerWaalsContact N-CD 3.32Å; L181-E409 PolarHBondContact N-OE1 2.91Å; L181-E409 VanDerWaalsContact N-OE1 3.13Å; L181-E409 PolarHBondContact N-OE2 2.81Å
182	V	88.6	Confident	90.9	Very high	45 Å²	45	21.3 Å²	21.3	27%	0.273	10%	0.102	S	C	.	.	H	α-helix	trans	-58.7	-38.4	177.3	63.6	0	0	0	0	112.6	P180 A186	P180-V182 VanDerWaalsContact C-N 3.29Å; P180-V182 HydrophobicContact CG-CG1 4.14Å; P180-V182 PolarHBondContact O-N 2.89Å; V182-A186 PolarHBondContact O-N 2.79Å
183	Q	92	Very high	90.9	Very high	12 Å²	12	25.7 Å²	25.7	6%	0.056	13%	0.133	C	C	.	.	H	α-helix	trans	-77.9	-34.2	175.3	-69.9	-174.2	-18	0	0	112	E146 F149 R179 P180 L181 A186 I187	E146-Q183 PolarHBondContact O-NE2 3.06Å; F149-Q183 HydrophobicContact CD1-CB 4.44Å; F149-Q183 HydrophobicContact CD1-CG 3.83Å; F149-Q183 HydrophobicContact CD2-CB 4.21Å; F149-Q183 HydrophobicContact CD2-CG 4.15Å; F149-Q183 HydrophobicContact CE1-CB 4.1Å; F149-Q183 HydrophobicContact CE1-CG 3.9Å; F149-Q183 HydrophobicContact CE2-CB 3.86Å; F149-Q183 HydrophobicContact CE2-CG 4.22Å; F149-Q183 HydrophobicContact CG-CB 4.48Å; F149-Q183 HydrophobicContact CG-CG 3.94Å; F149-Q183 HydrophobicContact CZ-CB 3.79Å; F149-Q183 HydrophobicContact CZ-CG 4.09Å; F149-Q183 WeakPolarHBondContact CZ-O 3.39Å; R179-Q183 HydrophobicContact CB-CB 4.02Å; P180-Q183 HydrophobicContact CG-CB 4.39Å; P180-Q183 HydrophobicContact CG-CG 4.25Å; P180-Q183 WeakPolarHBondContact O-CA 3.17Å; P180-Q183 PolarHBondContact O-N 3.23Å; L181-Q183 VanDerWaalsContact C-N 3.28Å; L181-Q183 PolarHBondContact O-N 2.81Å; Q183-A186 PolarHBondContact O-N 3.15Å; Q183-I187 WeakPolarHBondContact O-CG1 3.49Å; Q183-I187 PolarHBondContact O-N 3.23Å
184	R	93.4	Very high	90.9	Very high	3 Å²	3	28.7 Å²	28.7	1%	0.011	15%	0.147	C	C	.	.	H	α-helix	trans	-63.4	-46.6	172.9	-61.7	-166.8	-56.8	-90	1.6	111	M176 R179 P180 L181 A186 I187 L188 L218 E409	M176-R184 HydrophobicContact CE-CG 4.44Å; R179-R184 HydrophobicContact CB-CG 4.02Å; R179-R184 WeakPolarHBondContact O-CG 3.4Å; R179-R184 PolarHBondContact O-NH1 3.21Å; P180-R184 PolarHBondContact O-N 3.5Å; L181-R184 CarbonylContact O-C 3.42Å; L181-R184 PolarHBondContact O-N 3.03Å; L181-R184 VanDerWaalsContact O-N 3.12Å; R184-A186 VanDerWaalsContact C-N 3.34Å; R184-A186 PolarHBondContact O-N 2.99Å; R184-I187 WeakPolarHBondContact O-CA 3.47Å; R184-I187 WeakPolarHBondContact O-CB 3.26Å; R184-I187 PolarHBondContact O-N 3.13Å; R184-I187 VanDerWaalsContact O-N 3.1Å; R184-L188 WeakPolarHBondContact O-CG 3.18Å; R184-L188 PolarHBondContact O-N 3.03Å; R184-L218 WeakPolarHBondContact CD-O 3.36Å; R184-L218 PolarHBondContact NE-O 3.37Å; R184-E409 IonicContact CZ-OE1 3.14Å; R184-E409 VanDerWaalsContact CZ-OE1 3.23Å; R184-E409 IonicContact NH1-OE1 3.36Å; R184-E409 PolarHBondContact NH1-OE1 2.96Å; R184-E409 IonicContact NH2-OE1 2.73Å; R184-E409 PolarHBondContact NH2-OE1 2.73Å
185	V	91	Very high	91	Very high	3 Å²	3	28.3 Å²	28.3	2%	0.018	14%	0.143	C	C	.	.	H	α-helix	trans	-60	-41.7	176.7	171.4	0	0	0	0	111.6	F127 L181 I187 L188 Q189	F127-V185 HydrophobicContact CD1-CG2 4.42Å; F127-V185 HydrophobicContact CE1-CG1 3.97Å; F127-V185 HydrophobicContact CE1-CG2 4.39Å; F127-V185 HydrophobicContact CE2-CG1 4.44Å; F127-V185 HydrophobicContact CZ-CB 4.47Å; F127-V185 HydrophobicContact CZ-CG1 3.77Å; L181-V185 HydrophobicContact CD1-CG2 4.02Å; L181-V185 HydrophobicContact CG-CG2 4.37Å; L181-V185 WeakPolarHBondContact O-CB 3.48Å; L181-V185 WeakPolarHBondContact O-CG2 3.4Å; L181-V185 PolarHBondContact O-N 2.77Å; V185-I187 PolarHBondContact O-N 3.44Å; V185-L188 WeakPolarHBondContact O-CB 3.41Å; V185-L188 PolarHBondContact O-N 3.32Å; V185-Q189 HydrophobicContact CG1-CG 4.46Å; V185-Q189 VanDerWaalsContact CG1-NE2 3.34Å; V185-Q189 WeakPolarHBondContact O-CG 3.47Å; V185-Q189 PolarHBondContact O-N 3.03Å
186	A	91.7	Very high	90.9	Very high	26 Å²	26	31.4 Å²	31.4	22%	0.215	18%	0.175	C	C	.	.	H	α-helix	trans	-59.7	-44.8	173	0	0	0	0	0	112	F149 V151 V182 Q183 R184 L188 Q189 K190	F149-A186 HydrophobicContact CE1-CB 4.13Å; F149-A186 HydrophobicContact CZ-CB 4.17Å; V151-A186 VanDerWaalsContact CG2-C 3.45Å; V151-A186 HydrophobicContact CG2-CB 3.99Å; V151-A186 WeakPolarHBondContact CG2-O 3.33Å; V182-A186 PolarHBondContact O-N 2.79Å; Q183-A186 PolarHBondContact O-N 3.15Å; R184-A186 VanDerWaalsContact C-N 3.34Å; R184-A186 PolarHBondContact O-N 2.99Å; A186-L188 VanDerWaalsContact C-N 3.34Å; A186-L188 PolarHBondContact O-N 2.68Å; A186-Q189 PolarHBondContact O-N 2.7Å; A186-K190 VanDerWaalsContact O-CB 3.31Å; A186-K190 WeakPolarHBondContact O-CB 3.27Å; A186-K190 PolarHBondContact O-N 3.21Å
187	I	92.9	Very high	90.6	Very high	0 Å²	0	38 Å²	38	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-58.1	-44.8	173.3	-69.4	166	0	0	0	110.8	F149 V151 E154 C155 L158 V175 R179 Q183 R184 V185 K190 Y191 L199	F149-I187 HydrophobicContact CE2-CD1 4.04Å; F149-I187 HydrophobicContact CE2-CG1 4.04Å; F149-I187 HydrophobicContact CZ-CD1 4.47Å; F149-I187 HydrophobicContact CZ-CG1 4.04Å; V151-I187 HydrophobicContact CG2-CG1 4.19Å; E154-I187 HydrophobicContact CB-CD1 3.98Å; E154-I187 HydrophobicContact CB-CG1 4.05Å; E154-I187 HydrophobicContact CG-CD1 4.49Å; C155-I187 PolarHBondContact SG-O 3.32Å; L158-I187 HydrophobicContact CD1-CG2 3.53Å; V175-I187 HydrophobicContact CG1-CD1 4.04Å; R179-I187 HydrophobicContact CG-CD1 4.41Å; Q183-I187 WeakPolarHBondContact O-CG1 3.49Å; Q183-I187 PolarHBondContact O-N 3.23Å; R184-I187 WeakPolarHBondContact O-CA 3.47Å; R184-I187 WeakPolarHBondContact O-CB 3.26Å; R184-I187 PolarHBondContact O-N 3.13Å; R184-I187 VanDerWaalsContact O-N 3.1Å; V185-I187 PolarHBondContact O-N 3.44Å; I187-K190 PolarHBondContact O-N 2.92Å; I187-Y191 WeakPolarHBondContact O-CB 3.18Å; I187-Y191 PolarHBondContact O-N 3.38Å; I187-L199 HydrophobicContact CG2-CD2 4.09Å
188	L	92.6	Very high	90.6	Very high	4 Å²	4	39.9 Å²	39.9	2%	0.021	21%	0.213	C	C	.	.	H	α-helix	trans	-59.9	-49.5	-179.8	-63.7	173.8	0	0	0	112.2	C115 R184 V185 A186 R192 L199 P200 C219	C115-L188 HydrophobicContact CB-CB 3.89Å; C115-L188 HydrophobicContact CB-CD1 4.48Å; R184-L188 WeakPolarHBondContact O-CG 3.18Å; R184-L188 PolarHBondContact O-N 3.03Å; V185-L188 WeakPolarHBondContact O-CB 3.41Å; V185-L188 PolarHBondContact O-N 3.32Å; A186-L188 VanDerWaalsContact C-N 3.34Å; A186-L188 PolarHBondContact O-N 2.68Å; L188-R192 WeakPolarHBondContact O-CB 3.28Å; L188-R192 PolarHBondContact O-N 3.05Å; L188-R192 VanDerWaalsContact O-N 3.08Å; L188-L199 HydrophobicContact CD2-CB 3.8Å; L188-L199 HydrophobicContact CD2-CD2 3.9Å; L188-L199 HydrophobicContact CD2-CG 4.36Å; L188-P200 HydrophobicContact CD2-CG 4.38Å; L188-C219 HydrophobicContact CD1-CB 4.12Å; L188-C219 WeakPolarHBondContact CD1-O 3.08Å; L188-C219 HydrophobicContact CD2-CB 3.92Å
189	Q	91	Very high	91	Very high	19 Å²	19	37.7 Å²	37.7	9%	0.089	20%	0.203	C	C	.	.	H	α-helix	trans	-64.4	-47	-179.6	-67.8	168.8	-0.9	0	0	110.9	S114 C115 V185 A186 R192 S193	S114-Q189 PolarHBondContact O-NE2 2.87Å; C115-Q189 HydrophobicContact CB-CG 4.03Å; V185-Q189 HydrophobicContact CG1-CG 4.46Å; V185-Q189 VanDerWaalsContact CG1-NE2 3.34Å; V185-Q189 WeakPolarHBondContact O-CG 3.47Å; V185-Q189 PolarHBondContact O-N 3.03Å; A186-Q189 PolarHBondContact O-N 2.7Å; Q189-R192 PolarHBondContact O-N 2.97Å; Q189-S193 PolarHBondContact O-N 3.25Å
190	K	92.6	Very high	91.2	Very high	65 Å²	65	37.3 Å²	37.3	28%	0.283	20%	0.202	S	C	.	.	H	α-helix	trans	-68.3	-39.5	179.7	-169.7	78.5	-162.5	-157.5	0	112.5	V151 E152 A186 I187 R192 S193 M194	V151-K190 HydrophobicContact CG1-CB 4.34Å; V151-K190 HydrophobicContact CG1-CD 4.25Å; V151-K190 HydrophobicContact CG1-CG 4.13Å; V151-K190 HydrophobicContact CG2-CB 3.66Å; V151-K190 HydrophobicContact CG2-CG 4.14Å; E152-K190 WeakPolarHBondContact OE1-CD 3.44Å; E152-K190 WeakPolarHBondContact OE1-CE 3.49Å; E152-K190 IonicContact OE1-NZ 3.74Å; E152-K190 PolarHBondContact OE1-NZ 3.19Å; A186-K190 VanDerWaalsContact O-CB 3.31Å; A186-K190 WeakPolarHBondContact O-CB 3.27Å; A186-K190 PolarHBondContact O-N 3.21Å; I187-K190 PolarHBondContact O-N 2.92Å; K190-R192 VanDerWaalsContact C-N 3.34Å; K190-R192 PolarHBondContact O-N 2.96Å; K190-S193 WeakPolarHBondContact O-CB 3.1Å; K190-S193 PolarHBondContact O-N 3.1Å; K190-M194 HydrophobicContact CD-SD 4.46Å; K190-M194 HydrophobicContact CG-CG 4.26Å; K190-M194 HydrophobicContact CG-SD 3.82Å; K190-M194 WeakPolarHBondContact O-CB 3.39Å; K190-M194 WeakPolarHBondContact O-CG 3.18Å; K190-M194 PolarHBondContact O-N 3.13Å
191	Y	93	Very high	91.1	Very high	9 Å²	9	39.9 Å²	39.9	4%	0.035	22%	0.224	C	C	.	.	H	α-helix	trans	-62.5	-41.6	176	-170.8	-84.3	0	0	0	111.3	C155 L158 I187 M194 Y195 K197 L199	C155-Y191 HydrophobicContact CB-CD2 4.46Å; C155-Y191 PolarHBondContact SG-N 2.95Å; C155-Y191 VanDerWaalsContact SG-N 3.45Å; L158-Y191 HydrophobicContact CB-CD2 4.33Å; L158-Y191 HydrophobicContact CB-CE2 4.1Å; I187-Y191 WeakPolarHBondContact O-CB 3.18Å; I187-Y191 PolarHBondContact O-N 3.38Å; Y191-M194 PolarHBondContact O-N 2.84Å; Y191-Y195 HydrophobicContact CD1-CD2 4.07Å; Y191-Y195 AromaticContact CD2-CD2 3.5Å; Y191-Y195 HydrophobicContact CD2-CD2 3.5Å; Y191-Y195 AromaticContact CD2-CE2 3.67Å; Y191-Y195 HydrophobicContact CD2-CE2 3.67Å; Y191-Y195 HydrophobicContact CE1-CD2 4.01Å; Y191-Y195 AromaticContact CE2-CD2 3.42Å; Y191-Y195 HydrophobicContact CE2-CD2 3.42Å; Y191-Y195 VanDerWaalsContact CE2-CD2 3.42Å; Y191-Y195 AromaticContact CE2-CE2 3.6Å; Y191-Y195 HydrophobicContact CE2-CE2 3.6Å; Y191-Y195 HydrophobicContact CE2-CG 4.48Å; Y191-Y195 AromaticContact CG-CD2 3.82Å; Y191-Y195 HydrophobicContact CG-CD2 3.82Å; Y191-Y195 HydrophobicContact CG-CE2 4.38Å; Y191-Y195 AromaticContact CZ-CD2 3.68Å; Y191-Y195 PolarHBondContact O-N 2.88Å; Y191-K197 WeakPolarHBondContact CD1-O 3.35Å; Y191-L199 HydrophobicContact CD1-CB 3.91Å; Y191-L199 HydrophobicContact CD1-CD1 3.97Å; Y191-L199 HydrophobicContact CD2-CD1 4.02Å; Y191-L199 HydrophobicContact CE1-CB 4.37Å; Y191-L199 HydrophobicContact CE1-CD1 3.85Å; Y191-L199 HydrophobicContact CE2-CD1 3.89Å; Y191-L199 HydrophobicContact CG-CB 4.27Å; Y191-L199 HydrophobicContact CG-CD1 4.07Å
192	R	91.2	Very high	91.1	Very high	93 Å²	93	41.8 Å²	41.8	35%	0.351	23%	0.232	S	C	.	.	H	α-helix	trans	-60.6	-43.7	173.1	-175.3	-178.6	179	-173	-0.9	111.5	C115 L188 Q189 K190 G196 N198	C115-R192 PolarHBondContact O-NH1 3.43Å; L188-R192 WeakPolarHBondContact O-CB 3.28Å; L188-R192 PolarHBondContact O-N 3.05Å; L188-R192 VanDerWaalsContact O-N 3.08Å; Q189-R192 PolarHBondContact O-N 2.97Å; K190-R192 VanDerWaalsContact C-N 3.34Å; K190-R192 PolarHBondContact O-N 2.96Å; R192-G196 VanDerWaalsContact O-CA 3.27Å; R192-G196 WeakPolarHBondContact O-CA 3.22Å; R192-G196 PolarHBondContact O-N 3.2Å; R192-N198 WeakPolarHBondContact CD-OD1 3.47Å; R192-N198 PolarHBondContact NE-OD1 3.44Å
193	S	90.9	Very high	91.3	Very high	93 Å²	93	39.6 Å²	39.6	65%	0.65	22%	0.219	S	C	*	.	H	α-helix	trans	-64.1	-44.5	176	171.9	0	0	0	0	113.1	Q189 K190	Q189-S193 PolarHBondContact O-N 3.25Å; K190-S193 WeakPolarHBondContact O-CB 3.1Å; K190-S193 PolarHBondContact O-N 3.1Å
194	M	93.1	Very high	91.2	Very high	68 Å²	68	41.8 Å²	41.8	34%	0.335	23%	0.231	S	C	.	.	H	α-helix	trans	-77.1	-29.6	-175.6	-70.3	178.2	69.7	0	0	114.2	C155 E156 K190 Y191	C155-M194 HydrophobicContact CB-SD 3.7Å; E156-M194 HydrophobicContact CG-CE 4.04Å; K190-M194 HydrophobicContact CD-SD 4.46Å; K190-M194 HydrophobicContact CG-CG 4.26Å; K190-M194 HydrophobicContact CG-SD 3.82Å; K190-M194 WeakPolarHBondContact O-CB 3.39Å; K190-M194 WeakPolarHBondContact O-CG 3.18Å; K190-M194 PolarHBondContact O-N 3.13Å; Y191-M194 PolarHBondContact O-N 2.84Å
195	Y	91.3	Very high	91	Very high	86 Å²	86	45.3 Å²	45.3	34%	0.337	26%	0.257	S	S	.	.	H	α-helix	trans	-124.6	0.2	-171	-57.3	-61.4	0	0	0	114.9	C155 E156 Y191 K197	C155-Y195 HydrophobicContact CB-CE2 4.47Å; E156-Y195 WeakPolarHBondContact CA-OH 3.33Å; Y191-Y195 HydrophobicContact CD1-CD2 4.07Å; Y191-Y195 AromaticContact CD2-CD2 3.5Å; Y191-Y195 HydrophobicContact CD2-CD2 3.5Å; Y191-Y195 AromaticContact CD2-CE2 3.67Å; Y191-Y195 HydrophobicContact CD2-CE2 3.67Å; Y191-Y195 HydrophobicContact CE1-CD2 4.01Å; Y191-Y195 AromaticContact CE2-CD2 3.42Å; Y191-Y195 HydrophobicContact CE2-CD2 3.42Å; Y191-Y195 VanDerWaalsContact CE2-CD2 3.42Å; Y191-Y195 AromaticContact CE2-CE2 3.6Å; Y191-Y195 HydrophobicContact CE2-CE2 3.6Å; Y191-Y195 HydrophobicContact CE2-CG 4.48Å; Y191-Y195 AromaticContact CG-CD2 3.82Å; Y191-Y195 HydrophobicContact CG-CD2 3.82Å; Y191-Y195 HydrophobicContact CG-CE2 4.38Å; Y191-Y195 AromaticContact CZ-CD2 3.68Å; Y191-Y195 PolarHBondContact O-N 2.88Å; Y195-K197 PolarHBondContact O-N 2.97Å
196	G	89	Confident	91	Very high	66 Å²	66	48.4 Å²	48.4	68%	0.68	27%	0.27	S	S	*	.	S	Bend	trans	63.7	16.7	-179.5	0	0	0	0	0	114.6	R192	R192-G196 VanDerWaalsContact O-CA 3.27Å; R192-G196 WeakPolarHBondContact O-CA 3.22Å; R192-G196 PolarHBondContact O-N 3.2Å
197	K	86.3	Confident	90.9	Very high	137 Å²	137	47.6 Å²	47.6	60%	0.596	26%	0.261	S	S	*	.	S	Bend	trans	-137.2	138.8	-171.8	-67.3	-176.7	-176.1	-172.1	0	111.5	Y191 Y195	Y191-K197 WeakPolarHBondContact CD1-O 3.35Å; Y195-K197 PolarHBondContact O-N 2.97Å
198	N	89.2	Confident	90.5	Very high	40 Å²	40	52.6 Å²	52.6	21%	0.214	29%	0.288	C	S	.	.			trans	-73.4	126.4	177.4	-62.2	-28.9	0	0	0	110	V111 R192 P200 A201 K202	V111-N198 WeakPolarHBondContact CG2-ND2 3.27Å; R192-N198 WeakPolarHBondContact CD-OD1 3.47Å; R192-N198 PolarHBondContact NE-OD1 3.44Å; N198-P200 VanDerWaalsContact C-CD 3.49Å; N198-A201 HydrophobicContact CB-CB 4.42Å; N198-A201 PolarHBondContact O-N 2.93Å; N198-K202 PolarHBondContact O-N 3.46Å
199	L	91.6	Very high	90.3	Very high	1 Å²	1	53.9 Å²	53.9	1%	0.005	30%	0.303	C	S	.	.	H	α-helix	trans	-58.8	-38.4	-179.5	-171.9	67.6	0	0	0	114	L158 L162 M176 I187 L188 Y191 K202 F203	L158-L199 HydrophobicContact CD1-CD2 3.94Å; L162-L199 HydrophobicContact CD1-CD1 3.53Å; M176-L199 HydrophobicContact SD-CD2 4.38Å; I187-L199 HydrophobicContact CG2-CD2 4.09Å; L188-L199 HydrophobicContact CD2-CB 3.8Å; L188-L199 HydrophobicContact CD2-CD2 3.9Å; L188-L199 HydrophobicContact CD2-CG 4.36Å; Y191-L199 HydrophobicContact CD1-CB 3.91Å; Y191-L199 HydrophobicContact CD1-CD1 3.97Å; Y191-L199 HydrophobicContact CD2-CD1 4.02Å; Y191-L199 HydrophobicContact CE1-CB 4.37Å; Y191-L199 HydrophobicContact CE1-CD1 3.85Å; Y191-L199 HydrophobicContact CE2-CD1 3.89Å; Y191-L199 HydrophobicContact CG-CB 4.27Å; Y191-L199 HydrophobicContact CG-CD1 4.07Å; L199-K202 CarbonylContact O-C 3.59Å; L199-K202 WeakPolarHBondContact O-CA 3.44Å; L199-K202 WeakPolarHBondContact O-CB 3.31Å; L199-K202 PolarHBondContact O-N 2.92Å; L199-K202 VanDerWaalsContact O-N 3.09Å; L199-F203 HydrophobicContact CD1-CE1 4.12Å; L199-F203 HydrophobicContact CD1-CE2 4.19Å; L199-F203 HydrophobicContact CD1-CZ 3.86Å; L199-F203 HydrophobicContact CD2-CE2 3.74Å; L199-F203 HydrophobicContact CD2-CZ 3.77Å; L199-F203 HydrophobicContact CG-CD2 4.11Å; L199-F203 HydrophobicContact CG-CE1 4.39Å; L199-F203 HydrophobicContact CG-CE2 3.57Å; L199-F203 HydrophobicContact CG-CZ 3.72Å; L199-F203 PolarHBondContact O-N 3.36Å
200	P	91.6	Very high	90.2	Very high	5 Å²	5	54.1 Å²	54.1	3%	0.032	31%	0.306	C	S	.	.	H	α-helix	trans	-56.3	-52.5	174.3	-30.2	39.3	0	0	0	113.1	P112 L188 N198 K202 F203 N204 I216 C219	P112-P200 HydrophobicContact CG-CG 4.02Å; L188-P200 HydrophobicContact CD2-CG 4.38Å; N198-P200 VanDerWaalsContact C-CD 3.49Å; P200-K202 PolarHBondContact O-N 3.24Å; P200-F203 PolarHBondContact O-N 3.01Å; P200-N204 PolarHBondContact O-N 3.49Å; P200-I216 HydrophobicContact CB-CG2 3.81Å; P200-I216 WeakPolarHBondContact O-CD1 3.46Å; P200-C219 HydrophobicContact CG-CB 3.74Å
201	A	89.5	Confident	90.2	Very high	59 Å²	59	51 Å²	51	49%	0.488	29%	0.293	S	S	.	.	H	α-helix	trans	-62.1	-32.8	175.7	0	0	0	0	0	111.6	N198 N204 S205	N198-A201 HydrophobicContact CB-CB 4.42Å; N198-A201 PolarHBondContact O-N 2.93Å; A201-N204 PolarHBondContact O-N 2.95Å; A201-S205 WeakPolarHBondContact O-CB 3.44Å; A201-S205 PolarHBondContact O-N 2.79Å; A201-S205 PolarHBondContact O-OG 3.3Å
202	K	91.5	Very high	90.2	Very high	43 Å²	43	51.5 Å²	51.5	19%	0.187	30%	0.295	C	S	.	.	H	α-helix	trans	-67.6	-41.1	175.5	-175	58.4	-174.6	163.1	0	112.2	L162 N198 L199 P200 S205 K206	L162-K202 HydrophobicContact CB-CG 4.23Å; L162-K202 HydrophobicContact CD1-CG 4.16Å; L162-K202 WeakPolarHBondContact O-CE 3.36Å; L162-K202 PolarHBondContact O-NZ 3.23Å; N198-K202 PolarHBondContact O-N 3.46Å; L199-K202 CarbonylContact O-C 3.59Å; L199-K202 WeakPolarHBondContact O-CA 3.44Å; L199-K202 WeakPolarHBondContact O-CB 3.31Å; L199-K202 PolarHBondContact O-N 2.92Å; L199-K202 VanDerWaalsContact O-N 3.09Å; P200-K202 PolarHBondContact O-N 3.24Å; K202-S205 PolarHBondContact O-N 3Å; K202-S205 PolarHBondContact O-OG 3.35Å; K202-K206 WeakPolarHBondContact O-CB 3.22Å; K202-K206 PolarHBondContact O-N 3.44Å
203	F	92.9	Very high	90.2	Very high	0 Å²	0	47.7 Å²	47.7	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-62.6	-46.8	170.9	-67.9	-43	0	0	0	110.9	L158 L162 V172 M176 L199 P200 S205 K206 L207 L215 I216	L158-F203 HydrophobicContact CD2-CZ 4.45Å; L162-F203 HydrophobicContact CD1-CD1 4.19Å; L162-F203 HydrophobicContact CD1-CE1 3.78Å; L162-F203 HydrophobicContact CD2-CD1 3.95Å; L162-F203 HydrophobicContact CD2-CE1 4.01Å; L162-F203 HydrophobicContact CG-CE1 4.49Å; V172-F203 HydrophobicContact CG1-CE1 3.72Å; V172-F203 HydrophobicContact CG1-CZ 4.13Å; M176-F203 HydrophobicContact CE-CE2 4.35Å; M176-F203 HydrophobicContact CG-CZ 4.23Å; M176-F203 HydrophobicContact SD-CZ 4.49Å; L199-F203 HydrophobicContact CD1-CE1 4.12Å; L199-F203 HydrophobicContact CD1-CE2 4.19Å; L199-F203 HydrophobicContact CD1-CZ 3.86Å; L199-F203 HydrophobicContact CD2-CE2 3.74Å; L199-F203 HydrophobicContact CD2-CZ 3.77Å; L199-F203 HydrophobicContact CG-CD2 4.11Å; L199-F203 HydrophobicContact CG-CE1 4.39Å; L199-F203 HydrophobicContact CG-CE2 3.57Å; L199-F203 HydrophobicContact CG-CZ 3.72Å; L199-F203 PolarHBondContact O-N 3.36Å; P200-F203 PolarHBondContact O-N 3.01Å; F203-S205 PolarHBondContact O-N 2.98Å; F203-K206 PolarHBondContact O-N 2.9Å; F203-L207 HydrophobicContact CB-CD1 4.42Å; F203-L207 HydrophobicContact CD1-CD1 3.89Å; F203-L207 HydrophobicContact CG-CD1 4.47Å; F203-L207 PolarHBondContact O-N 3.01Å; F203-L215 HydrophobicContact CD1-CD1 4.23Å; F203-L215 HydrophobicContact CD2-CB 4.09Å; F203-L215 HydrophobicContact CE1-CD1 4.2Å; F203-L215 HydrophobicContact CE1-CD2 4.23Å; F203-L215 HydrophobicContact CE2-CB 4.28Å; F203-L215 HydrophobicContact CE2-CD2 3.94Å; F203-L215 HydrophobicContact CG-CB 4.35Å; F203-L215 HydrophobicContact CZ-CD2 3.78Å; F203-I216 HydrophobicContact CB-CD1 3.84Å; F203-I216 HydrophobicContact CB-CG1 3.66Å; F203-I216 HydrophobicContact CD2-CG1 4.04Å; F203-I216 HydrophobicContact CG-CG1 4.34Å
204	N	90	Very high	90.4	Very high	57 Å²	57	43.3 Å²	43.3	31%	0.305	25%	0.251	S	S	.	.	H	α-helix	trans	-58.6	-31.1	178.3	-161.7	50.4	0	0	0	113	F109 P200 A201 K212 I216	F109-N204 HydrophobicContact CD2-CB 4.25Å; F109-N204 HydrophobicContact CE2-CB 4.07Å; P200-N204 PolarHBondContact O-N 3.49Å; A201-N204 PolarHBondContact O-N 2.95Å; N204-K212 VanDerWaalsContact OD1-CD 3.3Å; N204-K212 WeakPolarHBondContact OD1-CD 3.34Å; N204-K212 WeakPolarHBondContact OD1-CE 3.43Å; N204-K212 PolarHBondContact OD1-NZ 3.39Å; N204-I216 HydrophobicContact CB-CD1 3.93Å
205	S	89.1	Confident	90.5	Very high	78 Å²	78	40 Å²	40	55%	0.545	24%	0.235	S	C	.	.	T	Hydrogen-bonded Turn	trans	-82.8	-1.1	176.3	75.1	0	0	0	0	115.8	A201 K202 F203	A201-S205 WeakPolarHBondContact O-CB 3.44Å; A201-S205 PolarHBondContact O-N 2.79Å; A201-S205 PolarHBondContact O-OG 3.3Å; K202-S205 PolarHBondContact O-N 3Å; K202-S205 PolarHBondContact O-OG 3.35Å; F203-S205 PolarHBondContact O-N 2.98Å
206	K	89.8	Confident	90.6	Very high	68 Å²	68	36 Å²	36	30%	0.296	22%	0.219	S	C	.	.	T	Hydrogen-bonded Turn	trans	-141.1	-12.7	-166.7	-88.7	-72.5	162.8	-173.9	0	116.2	R164 I165 V167 K202 F203	R164-K206 WeakPolarHBondContact O-CE 3.44Å; R164-K206 PolarHBondContact O-NZ 2.73Å; I165-K206 PolarHBondContact O-NZ 3.15Å; V167-K206 HydrophobicContact CG2-CB 4.17Å; V167-K206 HydrophobicContact CG2-CD 3.9Å; V167-K206 HydrophobicContact CG2-CG 4.47Å; K202-K206 WeakPolarHBondContact O-CB 3.22Å; K202-K206 PolarHBondContact O-N 3.44Å; F203-K206 PolarHBondContact O-N 2.9Å
207	L	89.8	Confident	90.9	Very high	8 Å²	8	32.8 Å²	32.8	4%	0.042	19%	0.186	C	C	.	.			trans	-137.3	152	-177.7	-59.1	172.9	0	0	0	108	V167 E169 F203 F211 K212 L215	V167-L207 HydrophobicContact CB-CD2 4.15Å; V167-L207 HydrophobicContact CG1-CD2 4.21Å; V167-L207 HydrophobicContact CG2-CD2 4.32Å; E169-L207 HydrophobicContact CG-CD2 3.97Å; F203-L207 HydrophobicContact CB-CD1 4.42Å; F203-L207 HydrophobicContact CD1-CD1 3.89Å; F203-L207 HydrophobicContact CG-CD1 4.47Å; F203-L207 PolarHBondContact O-N 3.01Å; L207-F211 HydrophobicContact CD1-CD1 4.06Å; L207-F211 HydrophobicContact CD1-CE1 3.78Å; L207-F211 HydrophobicContact CD2-CD1 4.14Å; L207-F211 HydrophobicContact CD2-CE1 3.99Å; L207-F211 HydrophobicContact CG-CE1 4.48Å; L207-K212 HydrophobicContact CB-CB 3.94Å; L207-K212 HydrophobicContact CB-CG 4.36Å; L207-K212 WeakPolarHBondContact O-CB 3.42Å; L207-K212 WeakPolarHBondContact O-CD 3.38Å; L207-K212 VanDerWaalsContact O-CG 3.25Å; L207-K212 WeakPolarHBondContact O-CG 3.33Å; L207-L215 HydrophobicContact CD1-CD1 3.35Å
208	N	85.5	Confident	91.3	Very high	106 Å²	106	26.3 Å²	26.3	57%	0.567	16%	0.158	S	C	*	.			trans	-119	170.3	178.1	-55	-39.5	0	0	0	111.5	K212 E458	N208-K212 VanDerWaalsContact C-CB 3.49Å; N208-K212 WeakPolarHBondContact O-CB 3.3Å; N208-K212 PolarHBondContact O-N 3.35Å; N208-E458 WeakPolarHBondContact CB-OE1 3.13Å
209	G	87.8	Confident	91.5	Very high	31 Å²	31	24.4 Å²	24.4	32%	0.32	15%	0.148	S	C	.	.	H	α-helix	trans	53.1	-158.2	169.4	0	0	0	0	0	115.8	F211 K212 D213 E458	G209-F211 PolarHBondContact O-N 2.95Å; G209-K212 WeakPolarHBondContact O-CA 3.48Å; G209-K212 VanDerWaalsContact O-CB 3.24Å; G209-K212 WeakPolarHBondContact O-CB 3.36Å; G209-K212 PolarHBondContact O-N 2.95Å; G209-D213 PolarHBondContact O-N 2.68Å; G209-D213 VanDerWaalsContact O-OD2 3.06Å; G209-E458 WeakPolarHBondContact CA-OE2 3.41Å; G209-E458 PolarHBondContact N-OE2 3.48Å
210	C	89.3	Confident	91.5	Very high	24 Å²	24	24.5 Å²	24.5	16%	0.162	15%	0.148	C	C	.	.	H	α-helix	trans	-52.9	-26	-174.3	58.4	0	0	0	0	115.2	D213 C214 L397 I401 C462	C210-D213 PolarHBondContact N-OD2 3.23Å; C210-C214 VanDerWaalsContact O-CB 3.28Å; C210-C214 WeakPolarHBondContact O-CB 3.35Å; C210-C214 PolarHBondContact O-N 3.4Å; C210-L397 HydrophobicContact CB-CB 4.33Å; C210-L397 HydrophobicContact CB-CD1 3.59Å; C210-L397 VanDerWaalsContact SG-CD1 3.57Å; C210-I401 HydrophobicContact CB-CD1 4.4Å; C210-C462 HydrophobicContact CB-CB 4.09Å; C210-C462 PolarHBondContact O-SG 3.3Å; C210-C462 VanDerWaalsContact O-SG 3.38Å; C210-C462 VanDerWaalsContact SG-CB 3.57Å
211	F	91.6	Very high	91.6	Very high	0 Å²	0	24.8 Å²	24.8	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-75.9	-43.6	175.7	-178.2	-121.3	0	0	0	113	E169 I173 L207 G209 D213 L215 E458 N461 C462 M465	E169-F211 HydrophobicContact CB-CE1 3.64Å; E169-F211 HydrophobicContact CB-CZ 3.98Å; E169-F211 HydrophobicContact CG-CD1 4.34Å; E169-F211 HydrophobicContact CG-CE1 3.7Å; E169-F211 VanDerWaalsContact OE1-CD1 3.24Å; E169-F211 WeakPolarHBondContact OE1-CD1 3.49Å; E169-F211 WeakPolarHBondContact OE1-CE1 3.44Å; I173-F211 HydrophobicContact CD1-CE2 3.77Å; I173-F211 HydrophobicContact CD1-CZ 4.03Å; I173-F211 HydrophobicContact CG1-CE2 3.55Å; I173-F211 HydrophobicContact CG1-CZ 3.77Å; L207-F211 HydrophobicContact CD1-CD1 4.06Å; L207-F211 HydrophobicContact CD1-CE1 3.78Å; L207-F211 HydrophobicContact CD2-CD1 4.14Å; L207-F211 HydrophobicContact CD2-CE1 3.99Å; L207-F211 HydrophobicContact CG-CE1 4.48Å; G209-F211 PolarHBondContact O-N 2.95Å; F211-D213 PolarHBondContact O-N 2.85Å; F211-L215 HydrophobicContact CD1-CD1 4.24Å; F211-L215 HydrophobicContact CD2-CD1 4.35Å; F211-L215 HydrophobicContact CE1-CD1 3.63Å; F211-L215 HydrophobicContact CE2-CD1 3.79Å; F211-L215 HydrophobicContact CE2-CG 4.21Å; F211-L215 HydrophobicContact CZ-CD1 3.39Å; F211-L215 HydrophobicContact CZ-CG 4.27Å; F211-L215 WeakPolarHBondContact O-CB 3.27Å; F211-L215 PolarHBondContact O-N 2.95Å; F211-L215 VanDerWaalsContact O-N 3.09Å; F211-E458 HydrophobicContact CB-CB 4.26Å; F211-E458 WeakPolarHBondContact CB-O 3.26Å; F211-N461 HydrophobicContact CB-CB 4.2Å; F211-N461 HydrophobicContact CD1-CB 4Å; F211-N461 VanDerWaalsContact CD2-C 3.48Å; F211-N461 HydrophobicContact CD2-CB 3.62Å; F211-N461 HydrophobicContact CE1-CB 4.29Å; F211-N461 HydrophobicContact CE2-CB 3.91Å; F211-N461 HydrophobicContact CG-CB 3.66Å; F211-N461 HydrophobicContact CZ-CB 4.24Å; F211-C462 HydrophobicContact CB-CB 4.3Å; F211-M465 HydrophobicContact CE2-CE 4.11Å
212	K	92.8	Very high	91.8	Very high	19 Å²	19	22.6 Å²	22.6	8%	0.083	13%	0.131	C	C	.	.	H	α-helix	trans	-52	-47.9	166.3	-178.1	-161.5	87.1	155	0	109.7	F106 N204 L207 N208 G209 L215 I216	F106-K212 PolarHBondContact O-NZ 3.03Å; N204-K212 VanDerWaalsContact OD1-CD 3.3Å; N204-K212 WeakPolarHBondContact OD1-CD 3.34Å; N204-K212 WeakPolarHBondContact OD1-CE 3.43Å; N204-K212 PolarHBondContact OD1-NZ 3.39Å; L207-K212 HydrophobicContact CB-CB 3.94Å; L207-K212 HydrophobicContact CB-CG 4.36Å; L207-K212 WeakPolarHBondContact O-CB 3.42Å; L207-K212 WeakPolarHBondContact O-CD 3.38Å; L207-K212 VanDerWaalsContact O-CG 3.25Å; L207-K212 WeakPolarHBondContact O-CG 3.33Å; N208-K212 VanDerWaalsContact C-CB 3.49Å; N208-K212 WeakPolarHBondContact O-CB 3.3Å; N208-K212 PolarHBondContact O-N 3.35Å; G209-K212 WeakPolarHBondContact O-CA 3.48Å; G209-K212 VanDerWaalsContact O-CB 3.24Å; G209-K212 WeakPolarHBondContact O-CB 3.36Å; G209-K212 PolarHBondContact O-N 2.95Å; K212-L215 PolarHBondContact O-N 3.12Å; K212-I216 HydrophobicContact CG-CD1 3.82Å; K212-I216 VanDerWaalsContact O-CG1 3.3Å; K212-I216 WeakPolarHBondContact O-CG1 3.16Å; K212-I216 PolarHBondContact O-N 3.21Å
213	D	92.3	Very high	91.9	Very high	13 Å²	13	20.8 Å²	20.8	7%	0.07	12%	0.124	C	C	.	.	H	α-helix	trans	-66.6	-49.4	-172.7	-57.4	-28.5	0	0	0	111.7	M105 F106 G209 C210 F211 L215 I216 A217	M105-D213 HydrophobicContact CB-CB 3.76Å; M105-D213 VanDerWaalsContact CB-CG 3.41Å; M105-D213 VanDerWaalsContact CB-OD2 3.31Å; M105-D213 WeakPolarHBondContact CB-OD2 3.27Å; M105-D213 HydrophobicContact CG-CB 4.16Å; M105-D213 HydrophobicContact SD-CB 3.77Å; F106-D213 HydrophobicContact CD2-CB 3.88Å; F106-D213 HydrophobicContact CE2-CB 3.76Å; F106-D213 WeakPolarHBondContact CE2-O 3.25Å; G209-D213 PolarHBondContact O-N 2.68Å; G209-D213 VanDerWaalsContact O-OD2 3.06Å; C210-D213 PolarHBondContact N-OD2 3.23Å; F211-D213 PolarHBondContact O-N 2.85Å; D213-L215 VanDerWaalsContact C-N 3.32Å; D213-L215 PolarHBondContact O-N 3.44Å; D213-I216 PolarHBondContact O-N 3.28Å; D213-A217 WeakPolarHBondContact O-CB 3.38Å; D213-A217 PolarHBondContact O-N 3.32Å
214	C	94.5	Very high	92	Very high	0 Å²	0	20.9 Å²	20.9	0%	0	12%	0.124	C	C	.	.	H	α-helix	trans	-60	-39.3	175	-176	0	0	0	0	112.5	C210 L218 I401	C210-C214 VanDerWaalsContact O-CB 3.28Å; C210-C214 WeakPolarHBondContact O-CB 3.35Å; C210-C214 PolarHBondContact O-N 3.4Å; C214-L218 WeakPolarHBondContact O-CG 3.43Å; C214-L218 PolarHBondContact O-N 3.45Å; C214-I401 HydrophobicContact CB-CD1 3.99Å; C214-I401 HydrophobicContact CB-CG1 4.02Å; C214-I401 HydrophobicContact CB-CG2 4.18Å
215	L	94.6	Very high	92.3	Very high	0 Å²	0	18.2 Å²	18.2	0%	0	11%	0.11	C	C	.	.	H	α-helix	trans	-66.1	-36.8	177.4	-96.2	168.2	0	0	0	113.5	V172 M176 F203 L207 F211 K212 D213 C219 M465	V172-L215 HydrophobicContact CG1-CD1 3.72Å; V172-L215 HydrophobicContact CG1-CD2 3.84Å; V172-L215 HydrophobicContact CG1-CG 4.46Å; M176-L215 HydrophobicContact CB-CD2 3.8Å; M176-L215 HydrophobicContact CG-CD2 3.63Å; F203-L215 HydrophobicContact CD1-CD1 4.23Å; F203-L215 HydrophobicContact CD2-CB 4.09Å; F203-L215 HydrophobicContact CE1-CD1 4.2Å; F203-L215 HydrophobicContact CE1-CD2 4.23Å; F203-L215 HydrophobicContact CE2-CB 4.28Å; F203-L215 HydrophobicContact CE2-CD2 3.94Å; F203-L215 HydrophobicContact CG-CB 4.35Å; F203-L215 HydrophobicContact CZ-CD2 3.78Å; L207-L215 HydrophobicContact CD1-CD1 3.35Å; F211-L215 HydrophobicContact CD1-CD1 4.24Å; F211-L215 HydrophobicContact CD2-CD1 4.35Å; F211-L215 HydrophobicContact CE1-CD1 3.63Å; F211-L215 HydrophobicContact CE2-CD1 3.79Å; F211-L215 HydrophobicContact CE2-CG 4.21Å; F211-L215 HydrophobicContact CZ-CD1 3.39Å; F211-L215 HydrophobicContact CZ-CG 4.27Å; F211-L215 WeakPolarHBondContact O-CB 3.27Å; F211-L215 PolarHBondContact O-N 2.95Å; F211-L215 VanDerWaalsContact O-N 3.09Å; K212-L215 PolarHBondContact O-N 3.12Å; D213-L215 VanDerWaalsContact C-N 3.32Å; D213-L215 PolarHBondContact O-N 3.44Å; L215-C219 PolarHBondContact O-SG 3.23Å; L215-M465 HydrophobicContact CD1-CE 4.39Å; L215-M465 HydrophobicContact CD2-CE 3.34Å; L215-M465 HydrophobicContact CG-CE 3.62Å
216	I	94	Very high	92.6	Very high	0 Å²	0	14.5 Å²	14.5	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-84.9	-31.6	-178.1	-57.5	167	0	0	0	111.2	F109 P200 F203 N204 K212 D213 L218 C219 Y220	F109-I216 HydrophobicContact CD1-CG2 3.86Å; F109-I216 HydrophobicContact CD2-CD1 4.39Å; F109-I216 HydrophobicContact CE1-CB 3.88Å; F109-I216 HydrophobicContact CE1-CD1 4.38Å; F109-I216 HydrophobicContact CE1-CG2 3.17Å; F109-I216 HydrophobicContact CE2-CB 4.45Å; F109-I216 HydrophobicContact CE2-CD1 3.4Å; F109-I216 HydrophobicContact CE2-CG1 4.49Å; F109-I216 HydrophobicContact CE2-CG2 4.11Å; F109-I216 HydrophobicContact CZ-CB 3.57Å; F109-I216 HydrophobicContact CZ-CD1 3.35Å; F109-I216 HydrophobicContact CZ-CG1 4.04Å; F109-I216 HydrophobicContact CZ-CG2 3.3Å; P200-I216 HydrophobicContact CB-CG2 3.81Å; P200-I216 WeakPolarHBondContact O-CD1 3.46Å; F203-I216 HydrophobicContact CB-CD1 3.84Å; F203-I216 HydrophobicContact CB-CG1 3.66Å; F203-I216 HydrophobicContact CD2-CG1 4.04Å; F203-I216 HydrophobicContact CG-CG1 4.34Å; N204-I216 HydrophobicContact CB-CD1 3.93Å; K212-I216 HydrophobicContact CG-CD1 3.82Å; K212-I216 VanDerWaalsContact O-CG1 3.3Å; K212-I216 WeakPolarHBondContact O-CG1 3.16Å; K212-I216 PolarHBondContact O-N 3.21Å; D213-I216 PolarHBondContact O-N 3.28Å; I216-L218 VanDerWaalsContact C-N 3.26Å; I216-L218 PolarHBondContact O-N 2.76Å; I216-C219 WeakPolarHBondContact O-CA 3.43Å; I216-C219 VanDerWaalsContact O-CB 3.29Å; I216-C219 WeakPolarHBondContact O-CB 3.26Å; I216-C219 PolarHBondContact O-N 2.95Å; I216-Y220 HydrophobicContact CG2-CE2 3.87Å; I216-Y220 VanDerWaalsContact O-CD2 3.23Å; I216-Y220 WeakPolarHBondContact O-CD2 3.4Å
217	A	94.8	Very high	92.9	Very high	0 Å²	0	11.2 Å²	11.2	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-52.8	-45	165.1	0	0	0	0	0	111.5	F106 D213 C219 Y220 F225 I401 V405	F106-A217 HydrophobicContact CZ-CB 4.37Å; D213-A217 WeakPolarHBondContact O-CB 3.38Å; D213-A217 PolarHBondContact O-N 3.32Å; A217-C219 PolarHBondContact O-N 2.92Å; A217-C219 VanDerWaalsContact O-N 3.13Å; A217-Y220 PolarHBondContact O-N 3.09Å; A217-F225 HydrophobicContact CB-CD1 4.25Å; A217-F225 HydrophobicContact CB-CD2 4.37Å; A217-F225 HydrophobicContact CB-CE1 3.74Å; A217-F225 HydrophobicContact CB-CE2 3.9Å; A217-F225 HydrophobicContact CB-CZ 3.56Å; A217-I401 HydrophobicContact CB-CG2 4.01Å; A217-V405 HydrophobicContact CB-CG1 4.25Å; A217-V405 HydrophobicContact CB-CG2 4.25Å
218	L	94.7	Very high	93.1	Very high	0 Å²	0	11 Å²	11	0%	0	7%	0.069	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63.8	-12.5	174.3	-77	169.8	0	0	0	115	M176 R184 C214 I216 V405 M465 L469	M176-L218 HydrophobicContact CE-CB 4.48Å; R184-L218 WeakPolarHBondContact CD-O 3.36Å; R184-L218 PolarHBondContact NE-O 3.37Å; C214-L218 WeakPolarHBondContact O-CG 3.43Å; C214-L218 PolarHBondContact O-N 3.45Å; I216-L218 VanDerWaalsContact C-N 3.26Å; I216-L218 PolarHBondContact O-N 2.76Å; L218-V405 HydrophobicContact CD2-CG1 4.2Å; L218-V405 HydrophobicContact CD2-CG2 4.1Å; L218-V405 HydrophobicContact CG-CG2 4.1Å; L218-M465 HydrophobicContact CD1-CE 4.2Å; L218-M465 HydrophobicContact CD1-CG 3.91Å; L218-M465 HydrophobicContact CD1-SD 3.95Å; L218-L469 HydrophobicContact CD1-CD1 4.19Å; L218-L469 HydrophobicContact CD1-CD2 4.25Å; L218-L469 HydrophobicContact CD2-CD1 3.88Å; L218-L469 HydrophobicContact CD2-CD2 3.7Å; L218-L469 HydrophobicContact CD2-CG 4.44Å; L218-L469 HydrophobicContact CG-CD1 4.34Å
219	C	93.6	Very high	93.5	Very high	1 Å²	1	6 Å²	6	1%	0.007	4%	0.042	C	C	.	.	T	Hydrogen-bonded Turn	trans	-90.3	-3.1	176.9	-61	0	0	0	0	113.8	P112 L188 P200 L215 I216 A217	P112-C219 WeakPolarHBondContact CG-O 3.47Å; L188-C219 HydrophobicContact CD1-CB 4.12Å; L188-C219 WeakPolarHBondContact CD1-O 3.08Å; L188-C219 HydrophobicContact CD2-CB 3.92Å; P200-C219 HydrophobicContact CG-CB 3.74Å; L215-C219 PolarHBondContact O-SG 3.23Å; I216-C219 WeakPolarHBondContact O-CA 3.43Å; I216-C219 VanDerWaalsContact O-CB 3.29Å; I216-C219 WeakPolarHBondContact O-CB 3.26Å; I216-C219 PolarHBondContact O-N 2.95Å; A217-C219 PolarHBondContact O-N 2.92Å; A217-C219 VanDerWaalsContact O-N 3.13Å
220	Y	93.1	Very high	93.8	Very high	2 Å²	2	4.5 Å²	4.5	1%	0.008	3%	0.027	C	C	.	.	S	Bend	trans	-104.8	154.6	173.9	-67.3	-72.1	0	0	0	110.6	F109 P110 P112 L181 I216 A217 E224 I228	F109-Y220 HydrophobicContact CD1-CE2 4.1Å; F109-Y220 VanDerWaalsContact CD1-OH 3.26Å; F109-Y220 WeakPolarHBondContact CD1-OH 2.96Å; F109-Y220 HydrophobicContact CE1-CE2 4.13Å; P110-Y220 WeakPolarHBondContact O-CE1 3.46Å; P110-Y220 PolarHBondContact O-OH 3.47Å; P112-Y220 HydrophobicContact CB-CD1 3.84Å; P112-Y220 HydrophobicContact CB-CE1 3.97Å; P112-Y220 HydrophobicContact CG-CD1 3.68Å; P112-Y220 HydrophobicContact CG-CE1 3.5Å; P112-Y220 VanDerWaalsContact CG-CE1 3.5Å; L181-Y220 WeakPolarHBondContact CD1-O 3.47Å; I216-Y220 HydrophobicContact CG2-CE2 3.87Å; I216-Y220 VanDerWaalsContact O-CD2 3.23Å; I216-Y220 WeakPolarHBondContact O-CD2 3.4Å; A217-Y220 PolarHBondContact O-N 3.09Å; Y220-E224 HydrophobicContact CD1-CB 3.87Å; Y220-E224 HydrophobicContact CG-CB 4.29Å; Y220-I228 HydrophobicContact CD1-CD1 3.82Å; Y220-I228 HydrophobicContact CD2-CD1 3.88Å; Y220-I228 HydrophobicContact CE1-CD1 3.53Å; Y220-I228 HydrophobicContact CE2-CD1 3.6Å; Y220-I228 HydrophobicContact CG-CD1 4Å; Y220-I228 VanDerWaalsContact CZ-CD1 3.45Å
221	T	92.9	Very high	94	Very high	11 Å²	11	5.5 Å²	5.5	7%	0.067	3%	0.027	C	C	.	.			trans	-67.6	154.9	158.8	60.9	0	0	0	0	109.9	F127 L181 A223 E224 F225	F127-T221 HydrophobicContact CB-CG2 4.11Å; F127-T221 HydrophobicContact CD1-CG2 3.9Å; F127-T221 HydrophobicContact CG-CG2 4.47Å; L181-T221 HydrophobicContact CD1-CG2 4.17Å; L181-T221 HydrophobicContact CD2-CG2 4.05Å; L181-T221 HydrophobicContact CG-CG2 4.42Å; T221-A223 PolarHBondContact O-N 3.41Å; T221-E224 WeakPolarHBondContact CB-OE2 3.49Å; T221-E224 VanDerWaalsContact CG2-OE2 3.31Å; T221-E224 WeakPolarHBondContact CG2-OE2 3.47Å; T221-E224 PolarHBondContact N-OE2 3.18Å; T221-E224 PolarHBondContact O-N 2.98Å; T221-E224 VanDerWaalsContact OG1-CD 3.23Å; T221-E224 WeakPolarHBondContact OG1-CG 3.32Å; T221-E224 PolarHBondContact OG1-N 3.12Å; T221-E224 PolarHBondContact OG1-OE2 3.49Å; T221-F225 PolarHBondContact O-N 3.3Å
222	P	93.2	Very high	93.9	Very high	13 Å²	13	8.2 Å²	8.2	8%	0.084	4%	0.037	C	C	.	.	H	α-helix	trans	-52.9	-37	177	-30.6	36.1	0	0	0	114	Y129 L181 F225 D226	Y129-P222 HydrophobicContact CD1-CB 4.04Å; Y129-P222 HydrophobicContact CD2-CB 3.4Å; Y129-P222 VanDerWaalsContact CD2-CB 3.4Å; Y129-P222 HydrophobicContact CD2-CG 4.26Å; Y129-P222 HydrophobicContact CE1-CB 4Å; Y129-P222 HydrophobicContact CE2-CB 3.34Å; Y129-P222 HydrophobicContact CG-CB 3.78Å; Y129-P222 HydrophobicContact CG-CG 4.35Å; Y129-P222 PolarHBondContact OH-O 3.45Å; L181-P222 VanDerWaalsContact CD2-CD 3.43Å; L181-P222 HydrophobicContact CD2-CG 4.41Å; P222-F225 PolarHBondContact O-N 3.3Å; P222-D226 VanDerWaalsContact O-CB 3.27Å; P222-D226 WeakPolarHBondContact O-CB 3.08Å; P222-D226 VanDerWaalsContact O-CG 3.24Å; P222-D226 PolarHBondContact O-N 2.87Å
223	A	94.2	Very high	93.7	Very high	6 Å²	6	7.3 Å²	7.3	5%	0.05	3%	0.034	C	C	.	.	H	α-helix	trans	-67.9	-39.4	176	0	0	0	0	0	113.3	Y129 T221 A227 R258 I259 V262	Y129-A223 HydrophobicContact CE1-CB 4.11Å; Y129-A223 WeakPolarHBondContact OH-CA 3.32Å; Y129-A223 PolarHBondContact OH-N 2.97Å; T221-A223 PolarHBondContact O-N 3.41Å; A223-A227 WeakPolarHBondContact O-CB 3.11Å; A223-A227 PolarHBondContact O-N 3Å; A223-A227 VanDerWaalsContact O-N 3.08Å; A223-R258 HydrophobicContact CB-CB 3.79Å; A223-I259 HydrophobicContact CB-CG1 4.27Å; A223-V262 HydrophobicContact CB-CG2 4.33Å; A223-V262 WeakPolarHBondContact O-CG2 3.46Å
224	E	94.9	Very high	93.6	Very high	2 Å²	2	8.4 Å²	8.4	1%	0.009	4%	0.039	C	C	.	.	H	α-helix	trans	-69.1	-38.1	174.7	-69.4	165.2	129.9	0	0	111.5	V113 S114 Y220 T221 A227 I228 V262 L266	V113-E224 WeakPolarHBondContact CA-OE1 3.39Å; V113-E224 WeakPolarHBondContact CB-OE1 3.45Å; V113-E224 PolarHBondContact N-OE1 3.23Å; S114-E224 WeakPolarHBondContact CB-OE2 3.21Å; S114-E224 PolarHBondContact N-OE1 3.08Å; S114-E224 PolarHBondContact OG-OE1 3.12Å; S114-E224 PolarHBondContact OG-OE2 3.34Å; Y220-E224 HydrophobicContact CD1-CB 3.87Å; Y220-E224 HydrophobicContact CG-CB 4.29Å; T221-E224 WeakPolarHBondContact CB-OE2 3.49Å; T221-E224 VanDerWaalsContact CG2-OE2 3.31Å; T221-E224 WeakPolarHBondContact CG2-OE2 3.47Å; T221-E224 PolarHBondContact N-OE2 3.18Å; T221-E224 PolarHBondContact O-N 2.98Å; T221-E224 VanDerWaalsContact OG1-CD 3.23Å; T221-E224 WeakPolarHBondContact OG1-CG 3.32Å; T221-E224 PolarHBondContact OG1-N 3.12Å; T221-E224 PolarHBondContact OG1-OE2 3.49Å; E224-A227 PolarHBondContact O-N 3.35Å; E224-I228 WeakPolarHBondContact O-CD1 3.46Å; E224-I228 VanDerWaalsContact O-CG1 3.29Å; E224-I228 WeakPolarHBondContact O-CG1 3.37Å; E224-I228 PolarHBondContact O-N 3.2Å; E224-I228 VanDerWaalsContact O-N 3.11Å; E224-V262 HydrophobicContact CG-CB 4.19Å; E224-V262 HydrophobicContact CG-CG1 4.19Å; E224-V262 HydrophobicContact CG-CG2 4.17Å; E224-L266 HydrophobicContact CB-CD1 4.11Å; E224-L266 HydrophobicContact CG-CD1 4.29Å
225	F	95.6	Very high	93	Very high	0 Å²	0	15.7 Å²	15.7	0%	0	7%	0.066	C	C	.	.	H	α-helix	trans	-72	-42.2	179.2	-175.1	-150.8	0	0	0	111.9	M105 F106 A217 T221 P222 A227 I228 E229 R402 V405 T406	M105-F225 HydrophobicContact CE-CE2 4.02Å; M105-F225 HydrophobicContact CE-CZ 3.77Å; F106-F225 HydrophobicContact CE1-CE2 4.25Å; F106-F225 HydrophobicContact CZ-CD2 4.49Å; F106-F225 AromaticContact CZ-CE2 3.84Å; F106-F225 HydrophobicContact CZ-CE2 3.84Å; A217-F225 HydrophobicContact CB-CD1 4.25Å; A217-F225 HydrophobicContact CB-CD2 4.37Å; A217-F225 HydrophobicContact CB-CE1 3.74Å; A217-F225 HydrophobicContact CB-CE2 3.9Å; A217-F225 HydrophobicContact CB-CZ 3.56Å; T221-F225 PolarHBondContact O-N 3.3Å; P222-F225 PolarHBondContact O-N 3.3Å; F225-A227 VanDerWaalsContact C-N 3.32Å; F225-A227 PolarHBondContact O-N 2.96Å; F225-I228 PolarHBondContact O-N 3.49Å; F225-I228 VanDerWaalsContact O-N 3.11Å; F225-E229 HydrophobicContact CD2-CG 4.06Å; F225-E229 HydrophobicContact CE2-CG 3.66Å; F225-E229 HydrophobicContact CZ-CG 4.12Å; F225-E229 PolarHBondContact O-N 3.11Å; F225-R402 HydrophobicContact CE1-CB 4.5Å; F225-R402 HydrophobicContact CZ-CB 4.4Å; F225-V405 HydrophobicContact CD1-CB 4.38Å; F225-V405 HydrophobicContact CD1-CG1 3.89Å; F225-V405 HydrophobicContact CE1-CB 3.98Å; F225-V405 HydrophobicContact CE1-CG1 3.95Å; F225-T406 HydrophobicContact CD1-CG2 3.8Å; F225-T406 HydrophobicContact CE1-CG2 4.26Å
226	D	96.3	Very high	92	Very high	0 Å²	0	17.3 Å²	17.3	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-60.4	-41	172.4	-78.3	-13.5	0	0	0	111.5	Y129 P222 I228 E229 L230 I247 R251 I259	Y129-D226 VanDerWaalsContact CE2-OD2 3.23Å; Y129-D226 WeakPolarHBondContact CE2-OD2 3.37Å; Y129-D226 VanDerWaalsContact CZ-OD2 3.31Å; Y129-D226 PolarHBondContact OH-OD2 3.32Å; P222-D226 VanDerWaalsContact O-CB 3.27Å; P222-D226 WeakPolarHBondContact O-CB 3.08Å; P222-D226 VanDerWaalsContact O-CG 3.24Å; P222-D226 PolarHBondContact O-N 2.87Å; D226-I228 VanDerWaalsContact C-N 3.3Å; D226-I228 PolarHBondContact O-N 3.19Å; D226-E229 PolarHBondContact O-N 3.26Å; D226-L230 WeakPolarHBondContact O-CB 3.32Å; D226-L230 VanDerWaalsContact O-CG 3.26Å; D226-L230 WeakPolarHBondContact O-CG 3.34Å; D226-L230 PolarHBondContact O-N 3.17Å; D226-I247 HydrophobicContact CB-CD1 4.43Å; D226-I247 HydrophobicContact CB-CG2 3.87Å; D226-R251 VanDerWaalsContact CG-NH2 3.33Å; D226-R251 IonicContact OD1-CZ 2.64Å; D226-R251 IonicContact OD1-NE 2.96Å; D226-R251 IonicContact OD1-NH2 2.79Å; D226-R251 PolarHBondContact OD1-NH2 3.48Å; D226-R251 IonicContact OD2-CZ 3.41Å; D226-R251 IonicContact OD2-NE 2.69Å; D226-R251 PolarHBondContact OD2-NE 3.09Å; D226-R251 IonicContact OD2-NH2 3.21Å; D226-R251 PolarHBondContact OD2-NH2 3.07Å; D226-R251 VanDerWaalsContact OD2-NH2 3.14Å; D226-I259 HydrophobicContact CB-CD1 3.74Å; D226-I259 HydrophobicContact CB-CG1 3.9Å
227	A	95.5	Very high	90.9	Very high	0 Å²	0	22 Å²	22	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-59.3	-39.5	173	0	0	0	0	0	112.3	A223 E224 F225 R231 I259 V262 Y263 L266 F267	A223-A227 WeakPolarHBondContact O-CB 3.11Å; A223-A227 PolarHBondContact O-N 3Å; A223-A227 VanDerWaalsContact O-N 3.08Å; E224-A227 PolarHBondContact O-N 3.35Å; F225-A227 VanDerWaalsContact C-N 3.32Å; F225-A227 PolarHBondContact O-N 2.96Å; A227-R231 WeakPolarHBondContact O-CB 3.12Å; A227-R231 PolarHBondContact O-N 2.88Å; A227-I259 HydrophobicContact CB-CG2 4.24Å; A227-V262 HydrophobicContact CB-CG2 4.06Å; A227-Y263 HydrophobicContact CB-CD2 3.71Å; A227-Y263 HydrophobicContact CB-CE2 4.44Å; A227-Y263 WeakPolarHBondContact O-CE2 3.31Å; A227-L266 HydrophobicContact CB-CD1 3.79Å; A227-F267 HydrophobicContact CB-CE2 4.34Å; A227-F267 WeakPolarHBondContact O-CE2 3.39Å
228	I	94.2	Very high	90.2	Very high	4 Å²	4	27.9 Å²	27.9	2%	0.021	14%	0.144	C	C	.	.	H	α-helix	trans	-70.5	-42.5	176.5	-68	161	0	0	0	112.1	F106 P110 Y220 E224 F225 D226 R231 R232 L266 F267	F106-I228 HydrophobicContact CD1-CG2 4.09Å; F106-I228 HydrophobicContact CE1-CG2 3.8Å; P110-I228 HydrophobicContact CG-CD1 4.09Å; P110-I228 HydrophobicContact CG-CG1 4.2Å; Y220-I228 HydrophobicContact CD1-CD1 3.82Å; Y220-I228 HydrophobicContact CD2-CD1 3.88Å; Y220-I228 HydrophobicContact CE1-CD1 3.53Å; Y220-I228 HydrophobicContact CE2-CD1 3.6Å; Y220-I228 HydrophobicContact CG-CD1 4Å; Y220-I228 VanDerWaalsContact CZ-CD1 3.45Å; E224-I228 WeakPolarHBondContact O-CD1 3.46Å; E224-I228 VanDerWaalsContact O-CG1 3.29Å; E224-I228 WeakPolarHBondContact O-CG1 3.37Å; E224-I228 PolarHBondContact O-N 3.2Å; E224-I228 VanDerWaalsContact O-N 3.11Å; F225-I228 PolarHBondContact O-N 3.49Å; F225-I228 VanDerWaalsContact O-N 3.11Å; D226-I228 VanDerWaalsContact C-N 3.3Å; D226-I228 PolarHBondContact O-N 3.19Å; I228-R231 PolarHBondContact O-N 2.8Å; I228-R232 WeakPolarHBondContact O-CB 3.41Å; I228-R232 WeakPolarHBondContact O-CG 3.49Å; I228-R232 PolarHBondContact O-N 3Å; I228-L266 HydrophobicContact CG1-CD1 4.47Å; I228-F267 HydrophobicContact CB-CZ 4.47Å; I228-F267 HydrophobicContact CG1-CZ 3.85Å
229	E	94.4	Very high	89.7	Confident	0 Å²	0	30 Å²	30	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-64.2	-42.1	175.7	-75.8	-75.4	135.3	0	0	111.5	F225 D226 R232 A233 T243 I247 K398 R402	F225-E229 HydrophobicContact CD2-CG 4.06Å; F225-E229 HydrophobicContact CE2-CG 3.66Å; F225-E229 HydrophobicContact CZ-CG 4.12Å; F225-E229 PolarHBondContact O-N 3.11Å; D226-E229 PolarHBondContact O-N 3.26Å; E229-R232 PolarHBondContact O-N 3.36Å; E229-R232 IonicContact OE1-CZ 2.7Å; E229-R232 IonicContact OE1-NH1 3.73Å; E229-R232 PolarHBondContact OE1-NH1 3.49Å; E229-A233 VanDerWaalsContact O-CB 3.31Å; E229-A233 WeakPolarHBondContact O-CB 3.39Å; E229-A233 PolarHBondContact O-N 3.33Å; E229-T243 HydrophobicContact CB-CG2 4.09Å; E229-I247 HydrophobicContact CB-CD1 3.63Å; E229-K398 WeakPolarHBondContact OE2-CE 3.2Å; E229-K398 IonicContact OE2-NZ 2.87Å; E229-R402 HydrophobicContact CG-CG 4.21Å; E229-R402 WeakPolarHBondContact OE2-CD 3.4Å; E229-R402 IonicContact OE2-CZ 2.66Å; E229-R402 IonicContact OE2-NH1 3.84Å; E229-R402 PolarHBondContact OE2-NH1 2.88Å
230	L	94.1	Very high	89.4	Confident	0 Å²	0	32.3 Å²	32.3	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-61.9	-51.4	173	-72.9	169.6	0	0	0	111.8	D226 R232 A233 M234 I244 I247 L248 I259 Y263 L272	D226-L230 WeakPolarHBondContact O-CB 3.32Å; D226-L230 VanDerWaalsContact O-CG 3.26Å; D226-L230 WeakPolarHBondContact O-CG 3.34Å; D226-L230 PolarHBondContact O-N 3.17Å; L230-R232 PolarHBondContact O-N 3.33Å; L230-A233 WeakPolarHBondContact O-CB 3.41Å; L230-A233 PolarHBondContact O-N 3.23Å; L230-A233 VanDerWaalsContact O-N 3.11Å; L230-M234 HydrophobicContact CB-CE 4.44Å; L230-M234 WeakPolarHBondContact O-CE 3.33Å; L230-M234 WeakPolarHBondContact O-CG 3.32Å; L230-M234 PolarHBondContact O-N 3.12Å; L230-I244 HydrophobicContact CD2-CB 4.41Å; L230-I244 HydrophobicContact CD2-CG1 4.15Å; L230-I244 HydrophobicContact CD2-CG2 4.39Å; L230-I247 HydrophobicContact CD1-CG2 3.91Å; L230-I247 HydrophobicContact CD2-CB 4.19Å; L230-I247 HydrophobicContact CD2-CD1 4.17Å; L230-I247 HydrophobicContact CD2-CG2 4.27Å; L230-I247 HydrophobicContact CG-CB 4.42Å; L230-I247 HydrophobicContact CG-CD1 3.92Å; L230-I247 HydrophobicContact CG-CG2 4.09Å; L230-L248 HydrophobicContact CD1-CD2 4.08Å; L230-L248 HydrophobicContact CD2-CD1 4.48Å; L230-L248 HydrophobicContact CD2-CD2 4.33Å; L230-L248 HydrophobicContact CD2-CG 4.16Å; L230-I259 HydrophobicContact CD1-CG2 3.89Å; L230-Y263 HydrophobicContact CB-CE2 4.42Å; L230-L272 HydrophobicContact CB-CD1 4.36Å; L230-L272 HydrophobicContact CD1-CD1 4.14Å; L230-L272 HydrophobicContact CD1-CD2 4Å
231	R	92.5	Very high	89.1	Confident	45 Å²	45	35 Å²	35	17%	0.17	18%	0.181	C	C	.	.	H	α-helix	trans	-60.4	-33.8	178.8	-177.6	63.1	-159	155.4	12.8	112.2	A227 I228 R235 Y263 F267 D275	A227-R231 WeakPolarHBondContact O-CB 3.12Å; A227-R231 PolarHBondContact O-N 2.88Å; I228-R231 PolarHBondContact O-N 2.8Å; R231-R235 VanDerWaalsContact O-CB 3.32Å; R231-R235 WeakPolarHBondContact O-CB 3.49Å; R231-R235 PolarHBondContact O-N 3.16Å; R231-Y263 WeakPolarHBondContact CA-OH 3.43Å; R231-Y263 HydrophobicContact CB-CE2 3.98Å; R231-Y263 WeakPolarHBondContact CB-OH 3.33Å; R231-Y263 WeakPolarHBondContact CD-OH 3.44Å; R231-F267 HydrophobicContact CB-CD2 4.07Å; R231-F267 HydrophobicContact CB-CE1 4.18Å; R231-F267 HydrophobicContact CB-CE2 3.56Å; R231-F267 HydrophobicContact CB-CZ 3.64Å; R231-F267 HydrophobicContact CG-CD1 4.01Å; R231-F267 HydrophobicContact CG-CD2 4.07Å; R231-F267 HydrophobicContact CG-CE1 3.91Å; R231-F267 HydrophobicContact CG-CE2 3.97Å; R231-F267 HydrophobicContact CG-CG 4.1Å; R231-F267 HydrophobicContact CG-CZ 3.9Å; R231-D275 IonicContact CZ-OD2 2.97Å; R231-D275 IonicContact NE-OD2 3.59Å; R231-D275 IonicContact NH1-OD1 2.74Å; R231-D275 PolarHBondContact NH1-OD1 2.98Å; R231-D275 IonicContact NH1-OD2 3.85Å; R231-D275 PolarHBondContact NH1-OD2 3.5Å
232	R	89.3	Confident	89	Confident	56 Å²	56	38.3 Å²	38.3	21%	0.211	20%	0.199	C	C	.	.	H	α-helix	trans	-72.8	-39.3	174.2	-80	175.5	50	-128.2	-9.6	112.7	M105 I228 E229 L230 M234 R235	M105-R232 WeakPolarHBondContact O-CD 3.31Å; M105-R232 PolarHBondContact O-NE 2.88Å; M105-R232 PolarHBondContact O-NH1 3.4Å; M105-R232 PolarHBondContact O-NH2 3.41Å; I228-R232 WeakPolarHBondContact O-CB 3.41Å; I228-R232 WeakPolarHBondContact O-CG 3.49Å; I228-R232 PolarHBondContact O-N 3Å; E229-R232 PolarHBondContact O-N 3.36Å; E229-R232 IonicContact OE1-CZ 2.7Å; E229-R232 IonicContact OE1-NH1 3.73Å; E229-R232 PolarHBondContact OE1-NH1 3.49Å; L230-R232 PolarHBondContact O-N 3.33Å; R232-M234 PolarHBondContact O-N 2.67Å; R232-R235 PolarHBondContact O-N 3.34Å
233	A	90.3	Very high	88.9	Confident	1 Å²	1	37.7 Å²	37.7	1%	0.008	20%	0.195	C	C	.	.	H	α-helix	trans	-61.7	-24.4	176.8	0	0	0	0	0	113.6	E229 L230 T239 D240 T243 I244	E229-A233 VanDerWaalsContact O-CB 3.31Å; E229-A233 WeakPolarHBondContact O-CB 3.39Å; E229-A233 PolarHBondContact O-N 3.33Å; L230-A233 WeakPolarHBondContact O-CB 3.41Å; L230-A233 PolarHBondContact O-N 3.23Å; L230-A233 VanDerWaalsContact O-N 3.11Å; A233-T239 WeakPolarHBondContact O-CA 3.14Å; A233-D240 HydrophobicContact CB-CB 3.78Å; A233-D240 PolarHBondContact O-N 2.96Å; A233-T243 HydrophobicContact CB-CG2 4.26Å; A233-I244 HydrophobicContact CB-CD1 4.09Å; A233-I244 HydrophobicContact CB-CG1 3.7Å
234	M	88.4	Confident	88.8	Confident	36 Å²	36	37.5 Å²	37.5	18%	0.177	19%	0.193	C	C	.	.	T	Hydrogen-bonded Turn	trans	-106.2	1	-178.8	-56.4	179.9	-59.9	0	0	114.3	L230 R232 I244 Y263 L272 D275 V276	L230-M234 HydrophobicContact CB-CE 4.44Å; L230-M234 WeakPolarHBondContact O-CE 3.33Å; L230-M234 WeakPolarHBondContact O-CG 3.32Å; L230-M234 PolarHBondContact O-N 3.12Å; R232-M234 PolarHBondContact O-N 2.67Å; M234-I244 HydrophobicContact CG-CD1 3.69Å; M234-I244 HydrophobicContact SD-CD1 4.35Å; M234-Y263 WeakPolarHBondContact CE-OH 3.39Å; M234-L272 HydrophobicContact CE-CD1 3.87Å; M234-D275 HydrophobicContact CE-CB 3.7Å; M234-D275 HydrophobicContact SD-CB 4.42Å; M234-D275 VanDerWaalsContact SD-O 3.38Å; M234-V276 HydrophobicContact CE-CG2 4.18Å; M234-V276 HydrophobicContact SD-CB 4.24Å; M234-V276 HydrophobicContact SD-CG2 3.36Å; M234-V276 WeakPolarHBondContact SD-CG2 3.38Å
235	R	83.2	Confident	88.6	Confident	153 Å²	153	37.9 Å²	37.9	58%	0.577	20%	0.195	S	C	*	.	T	Hydrogen-bonded Turn	trans	-98.3	-9.4	179.7	-177.3	175.3	174	-163.3	-1.8	113.3	D108 R231 R232	D108-R235 IonicContact OD2-CZ 3.64Å; D108-R235 VanDerWaalsContact OD2-CZ 3.23Å; D108-R235 IonicContact OD2-NH1 2.7Å; D108-R235 PolarHBondContact OD2-NH1 2.95Å; D108-R235 IonicContact OD2-NH2 3.94Å; D108-R235 PolarHBondContact OD2-NH2 2.95Å; R231-R235 VanDerWaalsContact O-CB 3.32Å; R231-R235 WeakPolarHBondContact O-CB 3.49Å; R231-R235 PolarHBondContact O-N 3.16Å; R232-R235 PolarHBondContact O-N 3.34Å
236	G	72.7	Confident	88.6	Confident	33 Å²	33	37.9 Å²	37.9	34%	0.34	20%	0.195	S	C	.	.	S	Bend	trans	-76.9	170.9	-179	0	0	0	0	0	113.9	D238	G236-D238 VanDerWaalsContact C-N 3.25Å
237	P	71.8	Confident	88.5	Confident	100 Å²	100	37.9 Å²	37.9	65%	0.649	20%	0.195	S	C	*	.	S	Bend	trans	-68	-29.4	166.8	29.9	-34.5	0	0	0	111.8	Y103	Y103-P237 VanDerWaalsContact OH-CD 3.29Å; Y103-P237 WeakPolarHBondContact OH-CD 3.38Å
238	D	79	Confident	88.4	Confident	122 Å²	122	38 Å²	38	65%	0.652	20%	0.195	S	C	*	.	S	Bend	trans	-114.4	135.8	171.8	-54.9	-71.7	0	0	0	109	G236 D240	G236-D238 VanDerWaalsContact C-N 3.25Å; D238-D240 PolarHBondContact O-N 3.49Å
239	T	84.3	Confident	88.2	Confident	44 Å²	44	38 Å²	38	27%	0.27	20%	0.196	S	C	.	.			trans	-70.2	127.4	173.4	-45.6	0	0	0	0	110.7	A233 K241 I244 D279	A233-T239 WeakPolarHBondContact O-CA 3.14Å; T239-K241 HydrophobicContact CG2-CG 4.02Å; T239-K241 PolarHBondContact O-N 3.13Å; T239-I244 HydrophobicContact CG2-CD1 3.37Å; T239-D279 WeakPolarHBondContact CB-OD2 3.39Å; T239-D279 VanDerWaalsContact CG2-OD2 3.22Å; T239-D279 WeakPolarHBondContact CG2-OD2 3.28Å; T239-D279 PolarHBondContact OG1-OD2 2.73Å
240	D	87.7	Confident	88.1	Confident	51 Å²	51	38 Å²	38	27%	0.273	20%	0.196	S	C	.	.			trans	-77.1	74.1	169.4	-175	-23.3	0	0	0	110.2	A233 D238 D242 T243 I244 K398	A233-D240 HydrophobicContact CB-CB 3.78Å; A233-D240 PolarHBondContact O-N 2.96Å; D238-D240 PolarHBondContact O-N 3.49Å; D240-D242 VanDerWaalsContact C-N 3.26Å; D240-D242 PolarHBondContact O-N 3.38Å; D240-T243 PolarHBondContact O-N 2.97Å; D240-T243 WeakPolarHBondContact OD1-CB 3.37Å; D240-T243 PolarHBondContact OD1-N 3.43Å; D240-T243 PolarHBondContact OD1-OG1 2.95Å; D240-T243 PolarHBondContact OD2-OG1 3.41Å; D240-I244 PolarHBondContact O-N 2.97Å; D240-I244 VanDerWaalsContact O-N 3.17Å; D240-K398 IonicContact OD2-NZ 3.23Å; D240-K398 PolarHBondContact OD2-NZ 3.38Å
241	K	86.9	Confident	88.1	Confident	57 Å²	57	38.2 Å²	38.2	25%	0.248	20%	0.197	C	C	.	.	H	α-helix	trans	-60.2	-34.2	-176.7	-66.6	-178.7	-175.9	173.4	0	112.5	T239 I244 I245 E281 F284	T239-K241 HydrophobicContact CG2-CG 4.02Å; T239-K241 PolarHBondContact O-N 3.13Å; K241-I244 PolarHBondContact O-N 3.34Å; K241-I245 WeakPolarHBondContact O-CB 3.37Å; K241-I245 WeakPolarHBondContact O-CD1 3.45Å; K241-I245 WeakPolarHBondContact O-CG1 3.42Å; K241-I245 PolarHBondContact O-N 2.99Å; K241-E281 IonicContact NZ-OE1 2.74Å; K241-E281 PolarHBondContact NZ-OE1 2.74Å; K241-E281 IonicContact NZ-OE2 3.81Å; K241-E281 PolarHBondContact NZ-OE2 3.45Å; K241-F284 HydrophobicContact CB-CE2 3.67Å; K241-F284 HydrophobicContact CB-CZ 3.84Å; K241-F284 HydrophobicContact CD-CD2 4.27Å; K241-F284 HydrophobicContact CD-CE2 3.97Å; K241-F284 HydrophobicContact CD-CZ 4.26Å; K241-F284 HydrophobicContact CG-CD2 4.47Å; K241-F284 HydrophobicContact CG-CE1 4.32Å; K241-F284 HydrophobicContact CG-CE2 3.71Å; K241-F284 HydrophobicContact CG-CZ 3.64Å
242	D	89.6	Confident	88.1	Confident	81 Å²	81	36.4 Å²	36.4	43%	0.433	19%	0.191	S	C	.	.	H	α-helix	trans	-68.6	-33.2	179.6	-177	59.3	0	0	0	112.5	D240 E246 K385	D240-D242 VanDerWaalsContact C-N 3.26Å; D240-D242 PolarHBondContact O-N 3.38Å; D242-E246 WeakPolarHBondContact O-CB 3.45Å; D242-E246 PolarHBondContact O-N 3.08Å; D242-E246 VanDerWaalsContact O-N 3.08Å; D242-K385 PolarHBondContact O-NZ 3.13Å; D242-K385 WeakPolarHBondContact OD1-CE 3.34Å; D242-K385 IonicContact OD1-NZ 3.62Å; D242-K385 PolarHBondContact OD1-NZ 3.49Å; D242-K385 IonicContact OD2-NZ 3.75Å; D242-K385 PolarHBondContact OD2-NZ 2.96Å
243	T	92.4	Very high	88.2	Confident	1 Å²	1	34.4 Å²	34.4	1%	0.006	18%	0.184	C	C	.	.	H	α-helix	trans	-71.2	-41.6	170.9	-62.6	0	0	0	0	111.9	E229 A233 D240 E246 I247 R402	E229-T243 HydrophobicContact CB-CG2 4.09Å; A233-T243 HydrophobicContact CB-CG2 4.26Å; D240-T243 PolarHBondContact O-N 2.97Å; D240-T243 WeakPolarHBondContact OD1-CB 3.37Å; D240-T243 PolarHBondContact OD1-N 3.43Å; D240-T243 PolarHBondContact OD1-OG1 2.95Å; D240-T243 PolarHBondContact OD2-OG1 3.41Å; T243-E246 PolarHBondContact O-N 3.01Å; T243-I247 HydrophobicContact CG2-CD1 3.91Å; T243-I247 WeakPolarHBondContact O-CG1 3.35Å; T243-I247 PolarHBondContact O-N 3.14Å; T243-I247 VanDerWaalsContact O-N 3.13Å; T243-R402 VanDerWaalsContact CG2-NH1 3.33Å; T243-R402 PolarHBondContact OG1-NH1 3.3Å
244	I	92.1	Very high	88.3	Confident	2 Å²	2	37.2 Å²	37.2	1%	0.01	20%	0.197	C	C	.	.	H	α-helix	trans	-63.4	-48.3	177.7	-65.3	172.2	0	0	0	110.8	L230 A233 M234 T239 D240 K241 E246 I247 L248 F284	L230-I244 HydrophobicContact CD2-CB 4.41Å; L230-I244 HydrophobicContact CD2-CG1 4.15Å; L230-I244 HydrophobicContact CD2-CG2 4.39Å; A233-I244 HydrophobicContact CB-CD1 4.09Å; A233-I244 HydrophobicContact CB-CG1 3.7Å; M234-I244 HydrophobicContact CG-CD1 3.69Å; M234-I244 HydrophobicContact SD-CD1 4.35Å; T239-I244 HydrophobicContact CG2-CD1 3.37Å; D240-I244 PolarHBondContact O-N 2.97Å; D240-I244 VanDerWaalsContact O-N 3.17Å; K241-I244 PolarHBondContact O-N 3.34Å; I244-E246 VanDerWaalsContact C-N 3.34Å; I244-E246 PolarHBondContact O-N 2.7Å; I244-I247 PolarHBondContact O-N 3.27Å; I244-L248 HydrophobicContact CG2-CD1 3.77Å; I244-L248 HydrophobicContact CG2-CG 4.36Å; I244-L248 WeakPolarHBondContact O-CB 3.26Å; I244-L248 WeakPolarHBondContact O-CG 3.09Å; I244-L248 PolarHBondContact O-N 3.19Å; I244-F284 HydrophobicContact CB-CZ 4.18Å; I244-F284 HydrophobicContact CD1-CE1 4.47Å; I244-F284 HydrophobicContact CD1-CZ 4.33Å; I244-F284 HydrophobicContact CG2-CE1 4.38Å; I244-F284 HydrophobicContact CG2-CZ 3.97Å
245	I	91.2	Very high	88.5	Confident	9 Å²	9	35.7 Å²	35.7	5%	0.046	19%	0.189	C	C	.	.	H	α-helix	trans	-57.6	-47.2	175.9	-70.3	165.6	0	0	0	110.1	K241 I247 C249 F284 T367 S370	K241-I245 WeakPolarHBondContact O-CB 3.37Å; K241-I245 WeakPolarHBondContact O-CD1 3.45Å; K241-I245 WeakPolarHBondContact O-CG1 3.42Å; K241-I245 PolarHBondContact O-N 2.99Å; I245-I247 PolarHBondContact O-N 3.48Å; I245-C249 WeakPolarHBondContact O-CB 3.42Å; I245-C249 PolarHBondContact O-N 3.48Å; I245-C249 PolarHBondContact O-SG 2.92Å; I245-F284 HydrophobicContact CD1-CE2 4.01Å; I245-F284 HydrophobicContact CG1-CE2 3.94Å; I245-T367 WeakPolarHBondContact CD1-OG1 3.36Å; I245-T367 HydrophobicContact CG1-CG2 4.19Å; I245-S370 WeakPolarHBondContact CG2-OG 3.31Å
246	E	93.9	Very high	89.1	Confident	0 Å²	0	28.6 Å²	28.6	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-56.3	-49.2	179.7	-171.6	-176.1	123.3	0	0	112.8	D242 T243 I244 S250 Y381 F382 K385 R402 I403	D242-E246 WeakPolarHBondContact O-CB 3.45Å; D242-E246 PolarHBondContact O-N 3.08Å; D242-E246 VanDerWaalsContact O-N 3.08Å; T243-E246 PolarHBondContact O-N 3.01Å; I244-E246 VanDerWaalsContact C-N 3.34Å; I244-E246 PolarHBondContact O-N 2.7Å; E246-S250 VanDerWaalsContact O-CB 3.28Å; E246-S250 WeakPolarHBondContact O-CB 3.33Å; E246-S250 PolarHBondContact O-N 3.16Å; E246-S250 PolarHBondContact O-OG 2.98Å; E246-Y381 WeakPolarHBondContact CA-OH 3.47Å; E246-Y381 HydrophobicContact CG-CE1 4.4Å; E246-F382 HydrophobicContact CG-CE1 4.19Å; E246-K385 HydrophobicContact CB-CD 4.42Å; E246-K385 HydrophobicContact CG-CD 3.94Å; E246-K385 WeakPolarHBondContact OE2-CD 3.38Å; E246-K385 WeakPolarHBondContact OE2-CE 3.35Å; E246-K385 IonicContact OE2-NZ 3.47Å; E246-K385 PolarHBondContact OE2-NZ 2.77Å; E246-R402 VanDerWaalsContact CD-NE 3.32Å; E246-R402 IonicContact OE1-CZ 2.95Å; E246-R402 IonicContact OE1-NE 2.7Å; E246-R402 PolarHBondContact OE1-NE 2.92Å; E246-R402 IonicContact OE1-NH2 3.16Å; E246-R402 IonicContact OE2-CZ 2.77Å; E246-R402 IonicContact OE2-NE 2.85Å; E246-R402 PolarHBondContact OE2-NE 3.27Å; E246-R402 IonicContact OE2-NH2 3.14Å; E246-R402 PolarHBondContact OE2-NH2 3.22Å; E246-I403 WeakPolarHBondContact OE1-CG1 3.35Å
247	I	95.2	Very high	90.1	Very high	0 Å²	0	31.8 Å²	31.8	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-72.1	-52.7	-175.4	-64.7	168.4	0	0	0	109.6	D226 E229 L230 T243 I244 I245 C249 S250 R251 I259	D226-I247 HydrophobicContact CB-CD1 4.43Å; D226-I247 HydrophobicContact CB-CG2 3.87Å; E229-I247 HydrophobicContact CB-CD1 3.63Å; L230-I247 HydrophobicContact CD1-CG2 3.91Å; L230-I247 HydrophobicContact CD2-CB 4.19Å; L230-I247 HydrophobicContact CD2-CD1 4.17Å; L230-I247 HydrophobicContact CD2-CG2 4.27Å; L230-I247 HydrophobicContact CG-CB 4.42Å; L230-I247 HydrophobicContact CG-CD1 3.92Å; L230-I247 HydrophobicContact CG-CG2 4.09Å; T243-I247 HydrophobicContact CG2-CD1 3.91Å; T243-I247 WeakPolarHBondContact O-CG1 3.35Å; T243-I247 PolarHBondContact O-N 3.14Å; T243-I247 VanDerWaalsContact O-N 3.13Å; I244-I247 PolarHBondContact O-N 3.27Å; I245-I247 PolarHBondContact O-N 3.48Å; I247-C249 PolarHBondContact O-N 3.46Å; I247-S250 PolarHBondContact O-N 2.95Å; I247-R251 HydrophobicContact CG2-CG 4.33Å; I247-R251 VanDerWaalsContact O-CB 3.31Å; I247-R251 WeakPolarHBondContact O-CB 3.36Å; I247-R251 WeakPolarHBondContact O-CD 3.36Å; I247-R251 VanDerWaalsContact O-CG 3.3Å; I247-R251 WeakPolarHBondContact O-CG 3.24Å; I247-R251 PolarHBondContact O-N 3.33Å; I247-I259 HydrophobicContact CG2-CD1 4.04Å
248	L	93.2	Very high	91.2	Very high	2 Å²	2	28.9 Å²	28.9	1%	0.01	14%	0.141	C	C	.	.	H	α-helix	trans	-74.4	-25.8	-171.6	-60.8	-175.7	0	0	0	113.7	L230 I244 I256 H288 L291 L292	L230-L248 HydrophobicContact CD1-CD2 4.08Å; L230-L248 HydrophobicContact CD2-CD1 4.48Å; L230-L248 HydrophobicContact CD2-CD2 4.33Å; L230-L248 HydrophobicContact CD2-CG 4.16Å; I244-L248 HydrophobicContact CG2-CD1 3.77Å; I244-L248 HydrophobicContact CG2-CG 4.36Å; I244-L248 WeakPolarHBondContact O-CB 3.26Å; I244-L248 WeakPolarHBondContact O-CG 3.09Å; I244-L248 PolarHBondContact O-N 3.19Å; L248-I256 HydrophobicContact CD2-CD1 3.68Å; L248-H288 HydrophobicContact CD1-CB 3.8Å; L248-L291 HydrophobicContact CB-CD1 4.26Å; L248-L292 HydrophobicContact CD1-CD1 4.42Å; L248-L292 HydrophobicContact CD1-CD2 4.41Å; L248-L292 HydrophobicContact CD1-CG 4.2Å; L248-L292 HydrophobicContact CD2-CD2 3.64Å; L248-L292 HydrophobicContact CD2-CG 4.22Å
249	C	90.8	Very high	91.9	Very high	4 Å²	4	23.1 Å²	23.1	3%	0.027	11%	0.11	C	C	.	.	H	α-helix	trans	-85.9	-20	178.9	-55.1	0	0	0	0	113.6	I245 I247 I371	I245-C249 WeakPolarHBondContact O-CB 3.42Å; I245-C249 PolarHBondContact O-N 3.48Å; I245-C249 PolarHBondContact O-SG 2.92Å; I247-C249 PolarHBondContact O-N 3.46Å; C249-I371 HydrophobicContact CB-CG1 3.75Å; C249-I371 WeakPolarHBondContact SG-CG1 3.49Å
250	S	92.4	Very high	92.5	Very high	0 Å²	0	23.6 Å²	23.6	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-107.1	-12.9	-174.3	71.1	0	0	0	0	116.1	E246 I247 C374 F382	E246-S250 VanDerWaalsContact O-CB 3.28Å; E246-S250 WeakPolarHBondContact O-CB 3.33Å; E246-S250 PolarHBondContact O-N 3.16Å; E246-S250 PolarHBondContact O-OG 2.98Å; I247-S250 PolarHBondContact O-N 2.95Å; S250-C374 VanDerWaalsContact CA-SG 3.52Å; S250-F382 WeakPolarHBondContact OG-CZ 3.17Å
251	R	93	Very high	92.8	Very high	5 Å²	5	25.7 Å²	25.7	2%	0.019	12%	0.119	C	C	.	.	S	Bend	trans	-83.6	142.1	180	-84.6	35.1	172.2	-178	2.1	110.2	Y129 D226 I247 H255 I256 I259 T406	Y129-R251 HydrophobicContact CE2-CG 4.38Å; D226-R251 VanDerWaalsContact CG-NH2 3.33Å; D226-R251 IonicContact OD1-CZ 2.64Å; D226-R251 IonicContact OD1-NE 2.96Å; D226-R251 IonicContact OD1-NH2 2.79Å; D226-R251 PolarHBondContact OD1-NH2 3.48Å; D226-R251 IonicContact OD2-CZ 3.41Å; D226-R251 IonicContact OD2-NE 2.69Å; D226-R251 PolarHBondContact OD2-NE 3.09Å; D226-R251 IonicContact OD2-NH2 3.21Å; D226-R251 PolarHBondContact OD2-NH2 3.07Å; D226-R251 VanDerWaalsContact OD2-NH2 3.14Å; I247-R251 HydrophobicContact CG2-CG 4.33Å; I247-R251 VanDerWaalsContact O-CB 3.31Å; I247-R251 WeakPolarHBondContact O-CB 3.36Å; I247-R251 WeakPolarHBondContact O-CD 3.36Å; I247-R251 VanDerWaalsContact O-CG 3.3Å; I247-R251 WeakPolarHBondContact O-CG 3.24Å; I247-R251 PolarHBondContact O-N 3.33Å; R251-H255 HydrophobicContact CB-CB 3.74Å; R251-H255 HydrophobicContact CG-CB 3.85Å; R251-I256 HydrophobicContact CB-CD1 3.75Å; R251-I256 HydrophobicContact CB-CG1 4Å; R251-I259 HydrophobicContact CG-CD1 3.95Å; R251-T406 PolarHBondContact NH2-OG1 2.92Å
252	T	91.8	Very high	93.1	Very high	7 Å²	7	23.8 Å²	23.8	4%	0.043	11%	0.113	C	C	.	.			trans	-71.2	166.6	173.4	69.1	0	0	0	0	110.3	P134 E254 H255 I256	P134-T252 HydrophobicContact CG-CG2 3.77Å; T252-E254 PolarHBondContact O-N 3.45Å; T252-E254 PolarHBondContact OG1-N 2.73Å; T252-H255 PolarHBondContact N-ND1 3.28Å; T252-H255 PolarHBondContact O-N 3.28Å; T252-H255 VanDerWaalsContact O-N 3.09Å; T252-H255 PolarHBondContact OG1-CD2 3.05Å; T252-H255 PolarHBondContact OG1-N 2.79Å; T252-H255 VanDerWaalsContact OG1-N 3.08Å; T252-H255 PolarHBondContact OG1-ND1 2.76Å; T252-H255 PolarHBondContact OG1-NE2 3.08Å; T252-I256 WeakPolarHBondContact O-CG1 3.46Å; T252-I256 PolarHBondContact O-N 3.21Å
253	N	92.8	Very high	93.3	Very high	14 Å²	14	20 Å²	20	8%	0.075	9%	0.092	C	C	.	.	H	α-helix	trans	-53.5	-41.6	172.7	-62.8	-49.1	0	0	0	111.5	I256 R257 A294 N295 R296 E298	N253-I256 PolarHBondContact O-N 3.44Å; N253-R257 VanDerWaalsContact CB-NH2 3.32Å; N253-R257 WeakPolarHBondContact O-CB 3.39Å; N253-R257 WeakPolarHBondContact O-CG 3.36Å; N253-R257 PolarHBondContact O-N 3.17Å; N253-A294 HydrophobicContact CB-CB 3.98Å; N253-A294 WeakPolarHBondContact CB-O 3.34Å; N253-A294 VanDerWaalsContact CG-C 3.5Å; N253-A294 VanDerWaalsContact CG-O 3.3Å; N253-A294 WeakPolarHBondContact O-CB 3.49Å; N253-A294 WeakPolarHBondContact OD1-CA 3.11Å; N253-A294 PolarHBondContact OD1-O 2.96Å; N253-N295 PolarHBondContact OD1-N 3.08Å; N253-R296 PolarHBondContact ND2-O 2.91Å; N253-R296 WeakPolarHBondContact OD1-CB 3.44Å; N253-R296 PolarHBondContact OD1-N 2.69Å; N253-E298 WeakPolarHBondContact CB-OE1 3.23Å; N253-E298 VanDerWaalsContact ND2-CD 3.31Å; N253-E298 WeakPolarHBondContact ND2-CG 3.43Å; N253-E298 PolarHBondContact ND2-OE1 3.27Å
254	E	91.1	Very high	93.4	Very high	60 Å²	60	22.1 Å²	22.1	28%	0.28	11%	0.106	S	C	.	.	H	α-helix	trans	-66.5	-38.5	178.3	179.1	56.6	-166.9	0	0	112.7	T252 R257 R258	T252-E254 PolarHBondContact O-N 3.45Å; T252-E254 PolarHBondContact OG1-N 2.73Å; E254-R257 PolarHBondContact O-N 2.94Å; E254-R257 IonicContact OE2-NH1 2.7Å; E254-R258 WeakPolarHBondContact O-CG 3.5Å; E254-R258 PolarHBondContact O-N 3.02Å; E254-R258 IonicContact OE1-CZ 3.83Å; E254-R258 IonicContact OE1-NE 2.68Å; E254-R258 PolarHBondContact OE1-NE 2.94Å; E254-R258 IonicContact OE1-NH2 3.92Å; E254-R258 PolarHBondContact OE1-NH2 2.91Å
255	H	93.8	Very high	93.4	Very high	4 Å²	4	27.3 Å²	27.3	2%	0.019	13%	0.129	C	C	.	.	H	α-helix	trans	-63	-45.1	172.4	-57.5	163.9	0	0	0	111	Y129 S132 R251 T252 R258 I259	Y129-H255 HydrophobicContact CD1-CB 4.05Å; Y129-H255 AromaticContact CD1-CD2 3.31Å; Y129-H255 WeakPolarHBondContact CD1-CD2 3.37Å; Y129-H255 AromaticContact CD1-CG 3.54Å; Y129-H255 AromaticContact CD1-NE2 3.78Å; Y129-H255 HydrophobicContact CE1-CB 3.63Å; Y129-H255 AromaticContact CE1-CD2 3.83Å; Y129-H255 AromaticContact CE1-CG 3.67Å; Y129-H255 AromaticContact CG-CD2 3.78Å; Y129-H255 AromaticContact CG-CE1 3.88Å; Y129-H255 AromaticContact CG-CG 3.88Å; Y129-H255 AromaticContact CG-ND1 3.95Å; Y129-H255 AromaticContact CG-NE2 3.78Å; Y129-H255 PolarHBondContact O-NE2 2.94Å; Y129-H255 VanDerWaalsContact O-NE2 3.17Å; S132-H255 PolarHBondContact O-NE2 3.14Å; S132-H255 VanDerWaalsContact O-NE2 3.16Å; S132-H255 PolarHBondContact OG-CD2 3.19Å; S132-H255 VanDerWaalsContact OG-CD2 3.28Å; S132-H255 PolarHBondContact OG-NE2 2.75Å; S132-H255 VanDerWaalsContact OG-NE2 3.14Å; R251-H255 HydrophobicContact CB-CB 3.74Å; R251-H255 HydrophobicContact CG-CB 3.85Å; T252-H255 PolarHBondContact N-ND1 3.28Å; T252-H255 PolarHBondContact O-N 3.28Å; T252-H255 VanDerWaalsContact O-N 3.09Å; T252-H255 PolarHBondContact OG1-CD2 3.05Å; T252-H255 PolarHBondContact OG1-N 2.79Å; T252-H255 VanDerWaalsContact OG1-N 3.08Å; T252-H255 PolarHBondContact OG1-ND1 2.76Å; T252-H255 PolarHBondContact OG1-NE2 3.08Å; H255-R258 PolarHBondContact O-N 2.75Å; H255-I259 VanDerWaalsContact O-CG1 3.31Å; H255-I259 WeakPolarHBondContact O-CG1 3.36Å; H255-I259 PolarHBondContact O-N 2.75Å
256	I	95	Very high	93.4	Very high	4 Å²	4	27.3 Å²	27.3	2%	0.021	13%	0.129	C	C	.	.	H	α-helix	trans	-60.8	-44.9	176.2	-64.3	-66	0	0	0	111.6	L248 R251 T252 N253 R258 I259 K260 L292 A294	L248-I256 HydrophobicContact CD2-CD1 3.68Å; R251-I256 HydrophobicContact CB-CD1 3.75Å; R251-I256 HydrophobicContact CB-CG1 4Å; T252-I256 WeakPolarHBondContact O-CG1 3.46Å; T252-I256 PolarHBondContact O-N 3.21Å; N253-I256 PolarHBondContact O-N 3.44Å; I256-R258 VanDerWaalsContact C-N 3.3Å; I256-R258 PolarHBondContact O-N 3.05Å; I256-I259 HydrophobicContact CD1-CD1 4.41Å; I256-I259 PolarHBondContact O-N 3.16Å; I256-K260 HydrophobicContact CG2-CD 4.16Å; I256-K260 PolarHBondContact O-N 2.87Å; I256-L292 HydrophobicContact CG2-CD2 4.25Å; I256-L292 WeakPolarHBondContact CG2-O 3.22Å; I256-A294 HydrophobicContact CB-CB 4.1Å; I256-A294 HydrophobicContact CG2-CB 3.87Å
257	R	94.9	Very high	93.3	Very high	101 Å²	101	28.8 Å²	28.8	38%	0.381	14%	0.135	S	C	.	.	H	α-helix	trans	-57.9	-41.9	175.2	-71.1	165.6	-159	145.6	1	111.2	N253 E254 N261 A294	N253-R257 VanDerWaalsContact CB-NH2 3.32Å; N253-R257 WeakPolarHBondContact O-CB 3.39Å; N253-R257 WeakPolarHBondContact O-CG 3.36Å; N253-R257 PolarHBondContact O-N 3.17Å; E254-R257 PolarHBondContact O-N 2.94Å; E254-R257 IonicContact OE2-NH1 2.7Å; R257-N261 VanDerWaalsContact O-CB 3.32Å; R257-N261 WeakPolarHBondContact O-CB 3.44Å; R257-N261 PolarHBondContact O-N 2.66Å; R257-A294 HydrophobicContact CG-CB 3.79Å; R257-A294 PolarHBondContact NH2-O 3.32Å
258	R	93.7	Very high	93	Very high	39 Å²	39	36.9 Å²	36.9	15%	0.147	18%	0.178	C	C	.	.	H	α-helix	trans	-67.2	-44	176.4	-70.4	176	-166.5	177.5	10.9	112.8	V126 G128 S132 A223 E254 H255 I256 K260 N261 V262	V126-R258 PolarHBondContact O-NH1 2.8Å; G128-R258 PolarHBondContact O-NH1 3.23Å; S132-R258 PolarHBondContact OG-NH1 2.6Å; A223-R258 HydrophobicContact CB-CB 3.79Å; E254-R258 WeakPolarHBondContact O-CG 3.5Å; E254-R258 PolarHBondContact O-N 3.02Å; E254-R258 IonicContact OE1-CZ 3.83Å; E254-R258 IonicContact OE1-NE 2.68Å; E254-R258 PolarHBondContact OE1-NE 2.94Å; E254-R258 IonicContact OE1-NH2 3.92Å; E254-R258 PolarHBondContact OE1-NH2 2.91Å; H255-R258 PolarHBondContact O-N 2.75Å; I256-R258 VanDerWaalsContact C-N 3.3Å; I256-R258 PolarHBondContact O-N 3.05Å; R258-K260 PolarHBondContact O-N 3.41Å; R258-N261 WeakPolarHBondContact O-CB 3.3Å; R258-N261 PolarHBondContact O-N 2.95Å; R258-N261 VanDerWaalsContact O-N 3.12Å; R258-V262 PolarHBondContact O-N 2.77Å; R258-V262 VanDerWaalsContact O-N 3.07Å
259	I	95.3	Very high	92.9	Very high	0 Å²	0	39.6 Å²	39.6	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-55.6	-52.8	174.4	-67	164.1	0	0	0	109.5	Y129 A223 D226 A227 L230 I247 R251 H255 I256 N261 V262 Y263 L272	Y129-I259 WeakPolarHBondContact OH-CD1 3.33Å; Y129-I259 WeakPolarHBondContact OH-CG1 3.31Å; A223-I259 HydrophobicContact CB-CG1 4.27Å; D226-I259 HydrophobicContact CB-CD1 3.74Å; D226-I259 HydrophobicContact CB-CG1 3.9Å; A227-I259 HydrophobicContact CB-CG2 4.24Å; L230-I259 HydrophobicContact CD1-CG2 3.89Å; I247-I259 HydrophobicContact CG2-CD1 4.04Å; R251-I259 HydrophobicContact CG-CD1 3.95Å; H255-I259 VanDerWaalsContact O-CG1 3.31Å; H255-I259 WeakPolarHBondContact O-CG1 3.36Å; H255-I259 PolarHBondContact O-N 2.75Å; I256-I259 HydrophobicContact CD1-CD1 4.41Å; I256-I259 PolarHBondContact O-N 3.16Å; I259-N261 VanDerWaalsContact C-N 3.25Å; I259-N261 PolarHBondContact O-N 2.93Å; I259-V262 WeakPolarHBondContact O-CG2 3.44Å; I259-V262 PolarHBondContact O-N 2.7Å; I259-V262 VanDerWaalsContact O-N 3.14Å; I259-Y263 WeakPolarHBondContact O-CB 3.37Å; I259-Y263 PolarHBondContact O-N 2.95Å; I259-L272 HydrophobicContact CG2-CD2 3.59Å
260	K	94.9	Very high	93	Very high	54 Å²	54	45 Å²	45	24%	0.235	23%	0.227	C	C	.	.	H	α-helix	trans	-60.3	-31.7	176.8	-73.1	176.4	59.5	173.2	0	113.2	I256 R258 P264 L272 E273 L292	I256-K260 HydrophobicContact CG2-CD 4.16Å; I256-K260 PolarHBondContact O-N 2.87Å; R258-K260 PolarHBondContact O-N 3.41Å; K260-P264 WeakPolarHBondContact O-CD 3.29Å; K260-L272 HydrophobicContact CG-CB 4.46Å; K260-L272 HydrophobicContact CG-CD2 4Å; K260-E273 IonicContact NZ-OE1 3.74Å; K260-E273 PolarHBondContact NZ-OE1 2.96Å; K260-L292 HydrophobicContact CD-CB 4.44Å; K260-L292 HydrophobicContact CD-CD2 4.25Å; K260-L292 WeakPolarHBondContact CD-O 3.42Å; K260-L292 HydrophobicContact CG-CD2 4.37Å; K260-L292 PolarHBondContact NZ-O 2.85Å
261	N	94.2	Very high	93	Very high	95 Å²	95	47.9 Å²	47.9	51%	0.508	24%	0.242	S	C	.	.	H	α-helix	trans	-73.4	-27.2	177.3	-167.9	-92	0	0	0	114	R257 R258 I259 K265	R257-N261 VanDerWaalsContact O-CB 3.32Å; R257-N261 WeakPolarHBondContact O-CB 3.44Å; R257-N261 PolarHBondContact O-N 2.66Å; R258-N261 WeakPolarHBondContact O-CB 3.3Å; R258-N261 PolarHBondContact O-N 2.95Å; R258-N261 VanDerWaalsContact O-N 3.12Å; I259-N261 VanDerWaalsContact C-N 3.25Å; I259-N261 PolarHBondContact O-N 2.93Å; N261-K265 VanDerWaalsContact O-CD 3.32Å; N261-K265 WeakPolarHBondContact O-CD 3.31Å; N261-K265 WeakPolarHBondContact O-CE 3.43Å; N261-K265 PolarHBondContact O-NZ 2.77Å; N261-K265 PolarHBondContact OD1-NZ 2.69Å
262	V	94.1	Very high	92.9	Very high	18 Å²	18	47.7 Å²	47.7	11%	0.109	24%	0.241	C	C	.	.	H	α-helix	trans	-96.9	-25.6	178.3	-58.8	0	0	0	0	113.4	A223 E224 A227 R258 I259 K265 L266	A223-V262 HydrophobicContact CB-CG2 4.33Å; A223-V262 WeakPolarHBondContact O-CG2 3.46Å; E224-V262 HydrophobicContact CG-CB 4.19Å; E224-V262 HydrophobicContact CG-CG1 4.19Å; E224-V262 HydrophobicContact CG-CG2 4.17Å; A227-V262 HydrophobicContact CB-CG2 4.06Å; R258-V262 PolarHBondContact O-N 2.77Å; R258-V262 VanDerWaalsContact O-N 3.07Å; I259-V262 WeakPolarHBondContact O-CG2 3.44Å; I259-V262 PolarHBondContact O-N 2.7Å; I259-V262 VanDerWaalsContact O-N 3.14Å; V262-K265 WeakPolarHBondContact O-CA 3.27Å; V262-K265 WeakPolarHBondContact O-CB 3.19Å; V262-K265 PolarHBondContact O-N 3.08Å; V262-L266 HydrophobicContact CB-CD1 4.26Å; V262-L266 HydrophobicContact CG2-CD1 4.09Å; V262-L266 WeakPolarHBondContact O-CG 3.16Å; V262-L266 PolarHBondContact O-N 2.86Å
263	Y	94.2	Very high	93	Very high	0 Å²	0	49.4 Å²	49.4	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-50.3	-55.6	-179	-156.2	-90.1	0	0	0	114.5	A227 L230 R231 M234 I259 K265 L266 F267 R270 L272 D275	A227-Y263 HydrophobicContact CB-CD2 3.71Å; A227-Y263 HydrophobicContact CB-CE2 4.44Å; A227-Y263 WeakPolarHBondContact O-CE2 3.31Å; L230-Y263 HydrophobicContact CB-CE2 4.42Å; R231-Y263 WeakPolarHBondContact CA-OH 3.43Å; R231-Y263 HydrophobicContact CB-CE2 3.98Å; R231-Y263 WeakPolarHBondContact CB-OH 3.33Å; R231-Y263 WeakPolarHBondContact CD-OH 3.44Å; M234-Y263 WeakPolarHBondContact CE-OH 3.39Å; I259-Y263 WeakPolarHBondContact O-CB 3.37Å; I259-Y263 PolarHBondContact O-N 2.95Å; Y263-K265 PolarHBondContact O-N 3.16Å; Y263-L266 PolarHBondContact O-N 3.35Å; Y263-L266 VanDerWaalsContact O-N 3.16Å; Y263-F267 AromaticContact CD1-CD2 3.89Å; Y263-F267 HydrophobicContact CD1-CD2 3.89Å; Y263-F267 AromaticContact CD2-CD2 3.96Å; Y263-F267 HydrophobicContact CD2-CD2 3.96Å; Y263-F267 AromaticContact CD2-CE2 3.92Å; Y263-F267 HydrophobicContact CD2-CE2 3.92Å; Y263-F267 AromaticContact CE1-CD2 3.83Å; Y263-F267 HydrophobicContact CE1-CD2 3.83Å; Y263-F267 AromaticContact CE2-CD2 3.89Å; Y263-F267 HydrophobicContact CE2-CD2 3.89Å; Y263-F267 AromaticContact CE2-CE2 3.81Å; Y263-F267 HydrophobicContact CE2-CE2 3.81Å; Y263-F267 AromaticContact CG-CD2 3.95Å; Y263-F267 HydrophobicContact CG-CD2 3.95Å; Y263-F267 HydrophobicContact CG-CE2 4.35Å; Y263-F267 AromaticContact CZ-CD2 3.84Å; Y263-F267 WeakPolarHBondContact O-CD2 3.38Å; Y263-F267 PolarHBondContact O-N 2.86Å; Y263-R270 HydrophobicContact CD1-CB 4.49Å; Y263-R270 HydrophobicContact CE1-CB 4.24Å; Y263-L272 HydrophobicContact CD1-CB 3.9Å; Y263-L272 HydrophobicContact CD2-CB 4.14Å; Y263-L272 HydrophobicContact CD2-CD1 4.02Å; Y263-L272 HydrophobicContact CD2-CD2 4.14Å; Y263-L272 HydrophobicContact CD2-CG 4.33Å; Y263-L272 HydrophobicContact CE1-CB 4.19Å; Y263-L272 HydrophobicContact CE1-CD1 4.44Å; Y263-L272 HydrophobicContact CE2-CB 4.43Å; Y263-L272 HydrophobicContact CE2-CD1 3.64Å; Y263-L272 HydrophobicContact CE2-CG 4.42Å; Y263-L272 HydrophobicContact CG-CB 3.87Å; Y263-D275 VanDerWaalsContact CE1-OD2 3.31Å; Y263-D275 WeakPolarHBondContact CE1-OD2 3.44Å; Y263-D275 PolarHBondContact OH-OD2 3.08Å
264	P	93	Very high	92.8	Very high	46 Å²	46	53.6 Å²	53.6	30%	0.299	27%	0.272	S	S	.	.	H	α-helix	trans	-65.1	-26.1	177.6	25.1	-34.7	0	0	0	113.2	K260 N268 G269 R270	K260-P264 WeakPolarHBondContact O-CD 3.29Å; P264-N268 PolarHBondContact O-N 3.4Å; P264-G269 PolarHBondContact O-N 3.11Å; P264-R270 VanDerWaalsContact CA-O 3.27Å; P264-R270 WeakPolarHBondContact CA-O 3.32Å; P264-R270 WeakPolarHBondContact CB-O 3.36Å
265	K	92.7	Very high	92.6	Very high	111 Å²	111	51.5 Å²	51.5	48%	0.483	26%	0.262	S	S	.	.	H	α-helix	trans	-75.3	-27.9	178.2	-56.5	176	-176.5	163.9	0	112.2	V113 N261 V262 Y263	V113-K265 HydrophobicContact CG1-CD 4.04Å; V113-K265 HydrophobicContact CG2-CB 3.8Å; N261-K265 VanDerWaalsContact O-CD 3.32Å; N261-K265 WeakPolarHBondContact O-CD 3.31Å; N261-K265 WeakPolarHBondContact O-CE 3.43Å; N261-K265 PolarHBondContact O-NZ 2.77Å; N261-K265 PolarHBondContact OD1-NZ 2.69Å; V262-K265 WeakPolarHBondContact O-CA 3.27Å; V262-K265 WeakPolarHBondContact O-CB 3.19Å; V262-K265 PolarHBondContact O-N 3.08Å; Y263-K265 PolarHBondContact O-N 3.16Å
266	L	91.1	Very high	92.3	Very high	9 Å²	9	51.6 Å²	51.6	5%	0.047	26%	0.263	C	S	.	.	H	α-helix	trans	-86.6	-33	175.8	-65.2	168	0	0	0	111.8	P110 V113 E224 A227 I228 V262 Y263	P110-L266 HydrophobicContact CB-CB 4.18Å; P110-L266 HydrophobicContact CB-CD2 3.85Å; P110-L266 WeakPolarHBondContact CB-O 3.29Å; P110-L266 HydrophobicContact CG-CB 4.1Å; P110-L266 HydrophobicContact CG-CD2 3.81Å; P110-L266 HydrophobicContact CG-CG 4.48Å; V113-L266 HydrophobicContact CG2-CD2 3.9Å; V113-L266 HydrophobicContact CG2-CG 4.27Å; E224-L266 HydrophobicContact CB-CD1 4.11Å; E224-L266 HydrophobicContact CG-CD1 4.29Å; A227-L266 HydrophobicContact CB-CD1 3.79Å; I228-L266 HydrophobicContact CG1-CD1 4.47Å; V262-L266 HydrophobicContact CB-CD1 4.26Å; V262-L266 HydrophobicContact CG2-CD1 4.09Å; V262-L266 WeakPolarHBondContact O-CG 3.16Å; V262-L266 PolarHBondContact O-N 2.86Å; Y263-L266 PolarHBondContact O-N 3.35Å; Y263-L266 VanDerWaalsContact O-N 3.16Å
267	F	91.4	Very high	91.6	Very high	31 Å²	31	54.4 Å²	54.4	14%	0.136	28%	0.278	C	S	.	.	T	Hydrogen-bonded Turn	trans	-122.9	46.6	-170.3	-51.5	-56.8	0	0	0	113.8	P110 A227 I228 R231 Y263 G269 R270	P110-F267 HydrophobicContact CG-CE1 4.09Å; A227-F267 HydrophobicContact CB-CE2 4.34Å; A227-F267 WeakPolarHBondContact O-CE2 3.39Å; I228-F267 HydrophobicContact CB-CZ 4.47Å; I228-F267 HydrophobicContact CG1-CZ 3.85Å; R231-F267 HydrophobicContact CB-CD2 4.07Å; R231-F267 HydrophobicContact CB-CE1 4.18Å; R231-F267 HydrophobicContact CB-CE2 3.56Å; R231-F267 HydrophobicContact CB-CZ 3.64Å; R231-F267 HydrophobicContact CG-CD1 4.01Å; R231-F267 HydrophobicContact CG-CD2 4.07Å; R231-F267 HydrophobicContact CG-CE1 3.91Å; R231-F267 HydrophobicContact CG-CE2 3.97Å; R231-F267 HydrophobicContact CG-CG 4.1Å; R231-F267 HydrophobicContact CG-CZ 3.9Å; Y263-F267 AromaticContact CD1-CD2 3.89Å; Y263-F267 HydrophobicContact CD1-CD2 3.89Å; Y263-F267 AromaticContact CD2-CD2 3.96Å; Y263-F267 HydrophobicContact CD2-CD2 3.96Å; Y263-F267 AromaticContact CD2-CE2 3.92Å; Y263-F267 HydrophobicContact CD2-CE2 3.92Å; Y263-F267 AromaticContact CE1-CD2 3.83Å; Y263-F267 HydrophobicContact CE1-CD2 3.83Å; Y263-F267 AromaticContact CE2-CD2 3.89Å; Y263-F267 HydrophobicContact CE2-CD2 3.89Å; Y263-F267 AromaticContact CE2-CE2 3.81Å; Y263-F267 HydrophobicContact CE2-CE2 3.81Å; Y263-F267 AromaticContact CG-CD2 3.95Å; Y263-F267 HydrophobicContact CG-CD2 3.95Å; Y263-F267 HydrophobicContact CG-CE2 4.35Å; Y263-F267 AromaticContact CZ-CD2 3.84Å; Y263-F267 WeakPolarHBondContact O-CD2 3.38Å; Y263-F267 PolarHBondContact O-N 2.86Å; F267-G269 VanDerWaalsContact C-N 3.29Å; F267-G269 PolarHBondContact O-N 3.11Å; F267-G269 VanDerWaalsContact O-N 3.13Å; F267-R270 HydrophobicContact CB-CB 4.24Å; F267-R270 WeakPolarHBondContact O-CB 3.34Å; F267-R270 WeakPolarHBondContact O-CG 3.39Å; F267-R270 PolarHBondContact O-N 3.45Å; F267-R270 VanDerWaalsContact O-N 3.1Å
268	N	89.3	Confident	90.6	Very high	170 Å²	170	55.7 Å²	55.7	91%	0.909	29%	0.293	S	S	*	.	T	Hydrogen-bonded Turn	trans	53.8	36.8	167	-61.9	91.9	0	0	0	115.3	P264	P264-N268 PolarHBondContact O-N 3.4Å
269	G	91.6	Very high	89.2	Confident	59 Å²	59	55.1 Å²	55.1	61%	0.608	29%	0.292	S	S	*	.	T	Hydrogen-bonded Turn	trans	90.3	4.4	177.7	0	0	0	0	0	115.9	P264 F267	P264-G269 PolarHBondContact O-N 3.11Å; F267-G269 VanDerWaalsContact C-N 3.29Å; F267-G269 PolarHBondContact O-N 3.11Å; F267-G269 VanDerWaalsContact O-N 3.13Å
270	R	92.2	Very high	87.5	Confident	119 Å²	119	61.3 Å²	61.3	45%	0.449	33%	0.33	S	S	.	.			trans	-60.2	141.4	170.7	-74.9	-177.5	173.7	-88.8	-12.6	112.1	Y263 P264 F267 D275	Y263-R270 HydrophobicContact CD1-CB 4.49Å; Y263-R270 HydrophobicContact CE1-CB 4.24Å; P264-R270 VanDerWaalsContact CA-O 3.27Å; P264-R270 WeakPolarHBondContact CA-O 3.32Å; P264-R270 WeakPolarHBondContact CB-O 3.36Å; F267-R270 HydrophobicContact CB-CB 4.24Å; F267-R270 WeakPolarHBondContact O-CB 3.34Å; F267-R270 WeakPolarHBondContact O-CG 3.39Å; F267-R270 PolarHBondContact O-N 3.45Å; F267-R270 VanDerWaalsContact O-N 3.1Å; R270-D275 WeakPolarHBondContact CD-OD2 3.43Å; R270-D275 IonicContact CZ-OD1 3.39Å; R270-D275 IonicContact NH1-OD1 3.53Å; R270-D275 PolarHBondContact NH1-OD1 3.16Å; R270-D275 IonicContact NH1-OD2 3.65Å
271	D	92.3	Very high	86.7	Confident	60 Å²	60	63.3 Å²	63.3	32%	0.321	34%	0.341	S	S	.	.			trans	-91.2	153.4	166.3	-170.9	68.4	0	0	0	111.8	E273 D274 D275	D271-E273 WeakPolarHBondContact OD2-CA 3.41Å; D271-E273 WeakPolarHBondContact OD2-CB 3.29Å; D271-E273 PolarHBondContact OD2-N 3.4Å; D271-D274 HydrophobicContact CB-CB 4.22Å; D271-D274 PolarHBondContact OD2-N 2.57Å; D271-D275 PolarHBondContact O-N 3.29Å
272	L	92.7	Very high	85.9	Confident	0 Å²	0	65.8 Å²	65.8	0%	0	35%	0.349	C	S	.	.	H	α-helix	trans	-89.9	-28.3	-177.5	174	58.5	0	0	0	113.4	L230 M234 I259 K260 Y263 V276 L292	L230-L272 HydrophobicContact CB-CD1 4.36Å; L230-L272 HydrophobicContact CD1-CD1 4.14Å; L230-L272 HydrophobicContact CD1-CD2 4Å; M234-L272 HydrophobicContact CE-CD1 3.87Å; I259-L272 HydrophobicContact CG2-CD2 3.59Å; K260-L272 HydrophobicContact CG-CB 4.46Å; K260-L272 HydrophobicContact CG-CD2 4Å; Y263-L272 HydrophobicContact CD1-CB 3.9Å; Y263-L272 HydrophobicContact CD2-CB 4.14Å; Y263-L272 HydrophobicContact CD2-CD1 4.02Å; Y263-L272 HydrophobicContact CD2-CD2 4.14Å; Y263-L272 HydrophobicContact CD2-CG 4.33Å; Y263-L272 HydrophobicContact CE1-CB 4.19Å; Y263-L272 HydrophobicContact CE1-CD1 4.44Å; Y263-L272 HydrophobicContact CE2-CB 4.43Å; Y263-L272 HydrophobicContact CE2-CD1 3.64Å; Y263-L272 HydrophobicContact CE2-CG 4.42Å; Y263-L272 HydrophobicContact CG-CB 3.87Å; L272-V276 HydrophobicContact CD1-CG2 4.17Å; L272-V276 WeakPolarHBondContact O-CB 3.2Å; L272-V276 WeakPolarHBondContact O-CG2 3.45Å; L272-V276 PolarHBondContact O-N 2.85Å; L272-L292 HydrophobicContact CD2-CD2 3.59Å; L272-L292 HydrophobicContact CG-CD1 4.15Å; L272-L292 HydrophobicContact CG-CD2 3.82Å
273	E	91.8	Very high	85.1	Confident	43 Å²	43	66.5 Å²	66.5	20%	0.201	35%	0.352	C	S	.	.	H	α-helix	trans	-70.2	-38.5	169.9	-71.7	-175.1	-146.7	0	0	110.2	K260 D271 V276 N277 L292	K260-E273 IonicContact NZ-OE1 3.74Å; K260-E273 PolarHBondContact NZ-OE1 2.96Å; D271-E273 WeakPolarHBondContact OD2-CA 3.41Å; D271-E273 WeakPolarHBondContact OD2-CB 3.29Å; D271-E273 PolarHBondContact OD2-N 3.4Å; E273-V276 PolarHBondContact O-N 2.78Å; E273-N277 WeakPolarHBondContact O-CB 3.47Å; E273-N277 PolarHBondContact O-N 3.43Å; E273-L292 HydrophobicContact CG-CB 3.74Å; E273-L292 HydrophobicContact CG-CD1 3.83Å; E273-L292 HydrophobicContact CG-CG 4.4Å
274	D	89.3	Confident	84.4	Confident	103 Å²	103	67.1 Å²	67.1	55%	0.551	35%	0.354	S	S	*	.	H	α-helix	trans	-61.4	-52.1	173.3	-75.5	-20.6	0	0	0	112.2	D271 V276 N277 D278	D271-D274 HydrophobicContact CB-CB 4.22Å; D271-D274 PolarHBondContact OD2-N 2.57Å; D274-V276 PolarHBondContact O-N 3.47Å; D274-N277 WeakPolarHBondContact O-CA 3.28Å; D274-N277 WeakPolarHBondContact O-CB 3.33Å; D274-N277 PolarHBondContact O-N 2.89Å; D274-D278 PolarHBondContact O-N 3.37Å
275	D	88.2	Confident	84	Confident	16 Å²	16	67.2 Å²	67.2	9%	0.086	35%	0.35	C	S	.	.	H	α-helix	trans	-63.3	-25	179.4	-84.3	-22.9	0	0	0	112.9	R231 M234 Y263 R270 D271	R231-D275 IonicContact CZ-OD2 2.97Å; R231-D275 IonicContact NE-OD2 3.59Å; R231-D275 IonicContact NH1-OD1 2.74Å; R231-D275 PolarHBondContact NH1-OD1 2.98Å; R231-D275 IonicContact NH1-OD2 3.85Å; R231-D275 PolarHBondContact NH1-OD2 3.5Å; M234-D275 HydrophobicContact CE-CB 3.7Å; M234-D275 HydrophobicContact SD-CB 4.42Å; M234-D275 VanDerWaalsContact SD-O 3.38Å; Y263-D275 VanDerWaalsContact CE1-OD2 3.31Å; Y263-D275 WeakPolarHBondContact CE1-OD2 3.44Å; Y263-D275 PolarHBondContact OH-OD2 3.08Å; R270-D275 WeakPolarHBondContact CD-OD2 3.43Å; R270-D275 IonicContact CZ-OD1 3.39Å; R270-D275 IonicContact NH1-OD1 3.53Å; R270-D275 PolarHBondContact NH1-OD1 3.16Å; R270-D275 IonicContact NH1-OD2 3.65Å; D271-D275 PolarHBondContact O-N 3.29Å
276	V	86	Confident	83.7	Confident	5 Å²	5	64.4 Å²	64.4	3%	0.03	34%	0.344	C	S	.	.	H	α-helix	trans	-83.1	-27.9	171.1	166	0	0	0	0	112.3	M234 L272 E273 D274 D278 D279 H288 I289 L292	M234-V276 HydrophobicContact CE-CG2 4.18Å; M234-V276 HydrophobicContact SD-CB 4.24Å; M234-V276 HydrophobicContact SD-CG2 3.36Å; M234-V276 WeakPolarHBondContact SD-CG2 3.38Å; L272-V276 HydrophobicContact CD1-CG2 4.17Å; L272-V276 WeakPolarHBondContact O-CB 3.2Å; L272-V276 WeakPolarHBondContact O-CG2 3.45Å; L272-V276 PolarHBondContact O-N 2.85Å; E273-V276 PolarHBondContact O-N 2.78Å; D274-V276 PolarHBondContact O-N 3.47Å; V276-D278 VanDerWaalsContact C-N 3.25Å; V276-D278 PolarHBondContact O-N 3.04Å; V276-D279 PolarHBondContact O-N 3.47Å; V276-H288 HydrophobicContact CG1-CB 3.95Å; V276-I289 HydrophobicContact CG1-CG1 4.24Å; V276-L292 HydrophobicContact CB-CD1 4.14Å; V276-L292 HydrophobicContact CG1-CD1 4.32Å; V276-L292 HydrophobicContact CG2-CD1 3.94Å
277	N	80.2	Confident	83.5	Confident	64 Å²	64	64 Å²	64	34%	0.342	34%	0.343	S	S	.	.	H	α-helix	trans	-71.7	-17.9	-179.7	170.3	86.6	0	0	0	112.6	E273 D274 D279 K285 I289	E273-N277 WeakPolarHBondContact O-CB 3.47Å; E273-N277 PolarHBondContact O-N 3.43Å; D274-N277 WeakPolarHBondContact O-CA 3.28Å; D274-N277 WeakPolarHBondContact O-CB 3.33Å; D274-N277 PolarHBondContact O-N 2.89Å; N277-D279 VanDerWaalsContact C-N 3.34Å; N277-D279 PolarHBondContact O-N 3.14Å; N277-K285 VanDerWaalsContact CG-NZ 3.32Å; N277-K285 WeakPolarHBondContact O-CD 3.44Å; N277-K285 VanDerWaalsContact O-CE 3.27Å; N277-K285 WeakPolarHBondContact O-CE 3.27Å; N277-K285 PolarHBondContact O-NZ 2.99Å; N277-K285 WeakPolarHBondContact OD1-CE 3.23Å; N277-K285 PolarHBondContact OD1-NZ 2.8Å; N277-I289 HydrophobicContact CB-CD1 4.2Å
278	D	74.3	Confident	83.4	Confident	128 Å²	128	62.6 Å²	62.6	68%	0.684	34%	0.336	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.5	-11.5	176.3	-77.5	-8.4	0	0	0	114.4	D274 V276	D274-D278 PolarHBondContact O-N 3.37Å; V276-D278 VanDerWaalsContact C-N 3.25Å; V276-D278 PolarHBondContact O-N 3.04Å
279	D	65.5	Low	83.5	Confident	27 Å²	27	55.6 Å²	55.6	14%	0.144	30%	0.299	C	S	.	.	S	Bend	trans	-76.4	148.6	176.9	-156.1	-20.4	0	0	0	112.7	T239 V276 N277	T239-D279 WeakPolarHBondContact CB-OD2 3.39Å; T239-D279 VanDerWaalsContact CG2-OD2 3.22Å; T239-D279 WeakPolarHBondContact CG2-OD2 3.28Å; T239-D279 PolarHBondContact OG1-OD2 2.73Å; V276-D279 PolarHBondContact O-N 3.47Å; N277-D279 VanDerWaalsContact C-N 3.34Å; N277-D279 PolarHBondContact O-N 3.14Å
280	T	59.4	Low	83.4	Confident	130 Å²	130	54.3 Å²	54.3	80%	0.798	28%	0.282	S	S	*	.	S	Bend	trans	-81.3	-24.6	-163.9	57.7	0	0	0	0	115.2	H282	T280-H282 PolarHBondContact O-N 3.3Å
281	E	76.6	Confident	83.5	Confident	96 Å²	96	49.4 Å²	49.4	45%	0.449	27%	0.265	S	S	.	.			trans	-86.5	101.5	-176.7	-84.7	169.5	-158.4	0	0	112	K241 L283 F284 K285	K241-E281 IonicContact NZ-OE1 2.74Å; K241-E281 PolarHBondContact NZ-OE1 2.74Å; K241-E281 IonicContact NZ-OE2 3.81Å; K241-E281 PolarHBondContact NZ-OE2 3.45Å; E281-L283 VanDerWaalsContact C-N 3.32Å; E281-L283 PolarHBondContact O-N 2.93Å; E281-L283 VanDerWaalsContact O-N 3.17Å; E281-F284 HydrophobicContact CB-CB 3.77Å; E281-F284 WeakPolarHBondContact O-CB 3.29Å; E281-F284 PolarHBondContact O-N 3.32Å; E281-F284 VanDerWaalsContact O-N 3.07Å; E281-K285 WeakPolarHBondContact O-CB 3.3Å; E281-K285 PolarHBondContact O-N 2.58Å
282	H	77.3	Confident	83.6	Confident	146 Å²	146	46.6 Å²	46.6	68%	0.676	25%	0.249	S	C	*	.	H	α-helix	trans	-49.8	-44.7	-174.6	-175.2	-83	0	0	0	114.5	T280 S286	T280-H282 PolarHBondContact O-N 3.3Å; H282-S286 PolarHBondContact CE1-OG 2.98Å; H282-S286 VanDerWaalsContact O-CB 3.25Å; H282-S286 WeakPolarHBondContact O-CB 3.49Å; H282-S286 PolarHBondContact O-N 3.41Å; H282-S286 PolarHBondContact O-OG 3.27Å
283	L	79.2	Confident	83.6	Confident	33 Å²	33	53.5 Å²	53.5	17%	0.173	28%	0.276	C	S	.	.	H	α-helix	trans	-65.3	-49.7	177.9	-180	66.5	0	0	0	112	E281 K285 S286 I287 E325 I330 L365	E281-L283 VanDerWaalsContact C-N 3.32Å; E281-L283 PolarHBondContact O-N 2.93Å; E281-L283 VanDerWaalsContact O-N 3.17Å; L283-K285 VanDerWaalsContact C-N 3.34Å; L283-K285 PolarHBondContact O-N 2.89Å; L283-S286 PolarHBondContact O-N 2.84Å; L283-I287 HydrophobicContact CD1-CD1 3.98Å; L283-I287 HydrophobicContact CD1-CG1 4.37Å; L283-I287 HydrophobicContact CG-CD1 3.98Å; L283-I287 WeakPolarHBondContact O-CG1 3.48Å; L283-I287 PolarHBondContact O-N 2.68Å; L283-E325 HydrophobicContact CD1-CB 4.1Å; L283-E325 HydrophobicContact CD1-CG 3.79Å; L283-E325 HydrophobicContact CD2-CG 3.8Å; L283-E325 HydrophobicContact CG-CG 4.26Å; L283-I330 HydrophobicContact CD1-CD1 3.67Å; L283-L365 HydrophobicContact CD2-CD1 4.45Å; L283-L365 HydrophobicContact CD2-CD2 3.94Å
284	F	79.3	Confident	83.7	Confident	13 Å²	13	51.7 Å²	51.7	6%	0.057	27%	0.268	C	S	.	.	H	α-helix	trans	-56.8	-50.4	179.8	177.6	-87.5	0	0	0	110.2	K241 I244 I245 E281 I287 H288	K241-F284 HydrophobicContact CB-CE2 3.67Å; K241-F284 HydrophobicContact CB-CZ 3.84Å; K241-F284 HydrophobicContact CD-CD2 4.27Å; K241-F284 HydrophobicContact CD-CE2 3.97Å; K241-F284 HydrophobicContact CD-CZ 4.26Å; K241-F284 HydrophobicContact CG-CD2 4.47Å; K241-F284 HydrophobicContact CG-CE1 4.32Å; K241-F284 HydrophobicContact CG-CE2 3.71Å; K241-F284 HydrophobicContact CG-CZ 3.64Å; I244-F284 HydrophobicContact CB-CZ 4.18Å; I244-F284 HydrophobicContact CD1-CE1 4.47Å; I244-F284 HydrophobicContact CD1-CZ 4.33Å; I244-F284 HydrophobicContact CG2-CE1 4.38Å; I244-F284 HydrophobicContact CG2-CZ 3.97Å; I245-F284 HydrophobicContact CD1-CE2 4.01Å; I245-F284 HydrophobicContact CG1-CE2 3.94Å; E281-F284 HydrophobicContact CB-CB 3.77Å; E281-F284 WeakPolarHBondContact O-CB 3.29Å; E281-F284 PolarHBondContact O-N 3.32Å; E281-F284 VanDerWaalsContact O-N 3.07Å; F284-I287 PolarHBondContact O-N 3.23Å; F284-H288 AromaticContact CD1-ND1 3.62Å; F284-H288 AromaticContact CD2-CE1 3.57Å; F284-H288 AromaticContact CD2-ND1 3.81Å; F284-H288 AromaticContact CE1-CE1 3.91Å; F284-H288 AromaticContact CE1-ND1 3.51Å; F284-H288 AromaticContact CE2-CE1 3.27Å; F284-H288 WeakPolarHBondContact CE2-CE1 3.45Å; F284-H288 AromaticContact CE2-ND1 3.71Å; F284-H288 AromaticContact CG-CE1 4Å; F284-H288 AromaticContact CG-ND1 3.75Å; F284-H288 AromaticContact CZ-CE1 3.44Å; F284-H288 VanDerWaalsContact CZ-CE1 3.44Å; F284-H288 WeakPolarHBondContact CZ-CE1 3.21Å; F284-H288 AromaticContact CZ-ND1 3.54Å; F284-H288 PolarHBondContact O-N 2.93Å; F284-H288 VanDerWaalsContact O-N 3.09Å; F284-H288 PolarHBondContact O-ND1 3.3Å
285	K	83.9	Confident	83.9	Confident	49 Å²	49	52.6 Å²	52.6	21%	0.213	27%	0.273	C	S	.	.	H	α-helix	trans	-56.7	-49	173.8	170.9	174.8	166.5	168.3	0	112.5	N277 E281 L283 I287 H288 I289	N277-K285 VanDerWaalsContact CG-NZ 3.32Å; N277-K285 WeakPolarHBondContact O-CD 3.44Å; N277-K285 VanDerWaalsContact O-CE 3.27Å; N277-K285 WeakPolarHBondContact O-CE 3.27Å; N277-K285 PolarHBondContact O-NZ 2.99Å; N277-K285 WeakPolarHBondContact OD1-CE 3.23Å; N277-K285 PolarHBondContact OD1-NZ 2.8Å; E281-K285 WeakPolarHBondContact O-CB 3.3Å; E281-K285 PolarHBondContact O-N 2.58Å; L283-K285 VanDerWaalsContact C-N 3.34Å; L283-K285 PolarHBondContact O-N 2.89Å; K285-I287 PolarHBondContact O-N 3.18Å; K285-H288 PolarHBondContact O-N 2.67Å; K285-I289 HydrophobicContact CG-CD1 3.68Å; K285-I289 WeakPolarHBondContact O-CB 3.34Å; K285-I289 WeakPolarHBondContact O-CG1 3.32Å; K285-I289 PolarHBondContact O-N 3.21Å
286	S	85.3	Confident	84.1	Confident	51 Å²	51	52.8 Å²	52.8	36%	0.357	27%	0.272	S	S	.	.	H	α-helix	trans	-60.6	-42.3	-179.1	-63.3	0	0	0	0	112.8	H282 L283 A290	H282-S286 PolarHBondContact CE1-OG 2.98Å; H282-S286 VanDerWaalsContact O-CB 3.25Å; H282-S286 WeakPolarHBondContact O-CB 3.49Å; H282-S286 PolarHBondContact O-N 3.41Å; H282-S286 PolarHBondContact O-OG 3.27Å; L283-S286 PolarHBondContact O-N 2.84Å; S286-A290 VanDerWaalsContact O-CB 3.3Å; S286-A290 WeakPolarHBondContact O-CB 3.46Å; S286-A290 PolarHBondContact O-N 3.12Å; S286-A290 VanDerWaalsContact O-N 3.1Å
287	I	88.4	Confident	84.4	Confident	2 Å²	2	55.4 Å²	55.4	1%	0.01	29%	0.286	C	S	.	.	H	α-helix	trans	-66.4	-46	177.4	-68.4	170.1	0	0	0	110.7	L283 F284 K285 A290 L291 I330 I334 T367 I368 I371	L283-I287 HydrophobicContact CD1-CD1 3.98Å; L283-I287 HydrophobicContact CD1-CG1 4.37Å; L283-I287 HydrophobicContact CG-CD1 3.98Å; L283-I287 WeakPolarHBondContact O-CG1 3.48Å; L283-I287 PolarHBondContact O-N 2.68Å; F284-I287 PolarHBondContact O-N 3.23Å; K285-I287 PolarHBondContact O-N 3.18Å; I287-A290 PolarHBondContact O-N 2.85Å; I287-L291 HydrophobicContact CG2-CD1 4Å; I287-L291 WeakPolarHBondContact O-CG 3.49Å; I287-L291 PolarHBondContact O-N 2.85Å; I287-I330 HydrophobicContact CD1-CD1 4.34Å; I287-I330 HydrophobicContact CD1-CG2 4.43Å; I287-I330 HydrophobicContact CG1-CG2 3.89Å; I287-I334 HydrophobicContact CB-CD1 4.34Å; I287-I334 HydrophobicContact CG1-CD1 4.36Å; I287-I334 HydrophobicContact CG2-CD1 3.98Å; I287-T367 HydrophobicContact CB-CG2 4.38Å; I287-T367 HydrophobicContact CD1-CG2 4.34Å; I287-T367 HydrophobicContact CG2-CG2 3.66Å; I287-I368 HydrophobicContact CD1-CD1 4.15Å; I287-I368 HydrophobicContact CD1-CG1 3.91Å; I287-I371 HydrophobicContact CG2-CD1 3.74Å
288	H	89.1	Confident	84.9	Confident	0 Å²	0	57.9 Å²	57.9	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-70.6	-37.5	-176.9	-69.5	115.1	0	0	0	113.2	L248 V276 F284 K285 A290 L291 L292	L248-H288 HydrophobicContact CD1-CB 3.8Å; V276-H288 HydrophobicContact CG1-CB 3.95Å; F284-H288 AromaticContact CD1-ND1 3.62Å; F284-H288 AromaticContact CD2-CE1 3.57Å; F284-H288 AromaticContact CD2-ND1 3.81Å; F284-H288 AromaticContact CE1-CE1 3.91Å; F284-H288 AromaticContact CE1-ND1 3.51Å; F284-H288 AromaticContact CE2-CE1 3.27Å; F284-H288 WeakPolarHBondContact CE2-CE1 3.45Å; F284-H288 AromaticContact CE2-ND1 3.71Å; F284-H288 AromaticContact CG-CE1 4Å; F284-H288 AromaticContact CG-ND1 3.75Å; F284-H288 AromaticContact CZ-CE1 3.44Å; F284-H288 VanDerWaalsContact CZ-CE1 3.44Å; F284-H288 WeakPolarHBondContact CZ-CE1 3.21Å; F284-H288 AromaticContact CZ-ND1 3.54Å; F284-H288 PolarHBondContact O-N 2.93Å; F284-H288 VanDerWaalsContact O-N 3.09Å; F284-H288 PolarHBondContact O-ND1 3.3Å; K285-H288 PolarHBondContact O-N 2.67Å; H288-A290 VanDerWaalsContact C-N 3.33Å; H288-A290 PolarHBondContact O-N 3.47Å; H288-L291 PolarHBondContact O-N 2.72Å; H288-L292 WeakPolarHBondContact O-CB 3.31Å; H288-L292 VanDerWaalsContact O-CG 3.32Å; H288-L292 WeakPolarHBondContact O-CG 3.34Å; H288-L292 PolarHBondContact O-N 3.19Å
289	I	90.2	Very high	85.5	Confident	24 Å²	24	58.9 Å²	58.9	12%	0.123	29%	0.294	C	S	.	.	H	α-helix	trans	-61.9	-42	170	-68.1	170.3	0	0	0	110.5	V276 N277 K285 L291 L292 R293	V276-I289 HydrophobicContact CG1-CG1 4.24Å; N277-I289 HydrophobicContact CB-CD1 4.2Å; K285-I289 HydrophobicContact CG-CD1 3.68Å; K285-I289 WeakPolarHBondContact O-CB 3.34Å; K285-I289 WeakPolarHBondContact O-CG1 3.32Å; K285-I289 PolarHBondContact O-N 3.21Å; I289-L291 VanDerWaalsContact C-N 3.31Å; I289-L291 PolarHBondContact O-N 2.82Å; I289-L292 PolarHBondContact O-N 2.67Å; I289-R293 WeakPolarHBondContact O-CG 3.35Å; I289-R293 PolarHBondContact O-N 2.99Å
290	A	91.2	Very high	86.5	Confident	31 Å²	31	62.9 Å²	62.9	26%	0.256	32%	0.32	S	S	.	.	H	α-helix	trans	-65.9	-31.1	177.8	0	0	0	0	0	113.3	S286 I287 H288 I334	S286-A290 VanDerWaalsContact O-CB 3.3Å; S286-A290 WeakPolarHBondContact O-CB 3.46Å; S286-A290 PolarHBondContact O-N 3.12Å; S286-A290 VanDerWaalsContact O-N 3.1Å; I287-A290 PolarHBondContact O-N 2.85Å; H288-A290 VanDerWaalsContact C-N 3.33Å; H288-A290 PolarHBondContact O-N 3.47Å; A290-I334 HydrophobicContact CB-CD1 3.82Å; A290-I334 HydrophobicContact CB-CG2 4.06Å
291	L	92.7	Very high	88	Confident	17 Å²	17	64.6 Å²	64.6	9%	0.089	32%	0.316	C	S	.	.	H	α-helix	trans	-71.4	-42.8	170.1	-70	164.3	0	0	0	112	L248 I287 H288 I289 R293 A294 I334 I371	L248-L291 HydrophobicContact CB-CD1 4.26Å; I287-L291 HydrophobicContact CG2-CD1 4Å; I287-L291 WeakPolarHBondContact O-CG 3.49Å; I287-L291 PolarHBondContact O-N 2.85Å; H288-L291 PolarHBondContact O-N 2.72Å; I289-L291 VanDerWaalsContact C-N 3.31Å; I289-L291 PolarHBondContact O-N 2.82Å; L291-R293 PolarHBondContact O-N 3.43Å; L291-R293 VanDerWaalsContact O-N 3.17Å; L291-A294 PolarHBondContact O-N 3.29Å; L291-I334 HydrophobicContact CD2-CG2 4.18Å; L291-I334 HydrophobicContact CG-CG2 4.46Å; L291-I371 HydrophobicContact CD1-CD1 4.26Å
292	L	94.3	Very high	88.8	Confident	0 Å²	0	63.3 Å²	63.3	0%	0	31%	0.312	C	S	.	.	H	α-helix	trans	-62	-21.2	179	-77	171.3	0	0	0	114.2	L248 I256 K260 L272 E273 V276 H288 I289 A294	L248-L292 HydrophobicContact CD1-CD1 4.42Å; L248-L292 HydrophobicContact CD1-CD2 4.41Å; L248-L292 HydrophobicContact CD1-CG 4.2Å; L248-L292 HydrophobicContact CD2-CD2 3.64Å; L248-L292 HydrophobicContact CD2-CG 4.22Å; I256-L292 HydrophobicContact CG2-CD2 4.25Å; I256-L292 WeakPolarHBondContact CG2-O 3.22Å; K260-L292 HydrophobicContact CD-CB 4.44Å; K260-L292 HydrophobicContact CD-CD2 4.25Å; K260-L292 WeakPolarHBondContact CD-O 3.42Å; K260-L292 HydrophobicContact CG-CD2 4.37Å; K260-L292 PolarHBondContact NZ-O 2.85Å; L272-L292 HydrophobicContact CD2-CD2 3.59Å; L272-L292 HydrophobicContact CG-CD1 4.15Å; L272-L292 HydrophobicContact CG-CD2 3.82Å; E273-L292 HydrophobicContact CG-CB 3.74Å; E273-L292 HydrophobicContact CG-CD1 3.83Å; E273-L292 HydrophobicContact CG-CG 4.4Å; V276-L292 HydrophobicContact CB-CD1 4.14Å; V276-L292 HydrophobicContact CG1-CD1 4.32Å; V276-L292 HydrophobicContact CG2-CD1 3.94Å; H288-L292 WeakPolarHBondContact O-CB 3.31Å; H288-L292 VanDerWaalsContact O-CG 3.32Å; H288-L292 WeakPolarHBondContact O-CG 3.34Å; H288-L292 PolarHBondContact O-N 3.19Å; I289-L292 PolarHBondContact O-N 2.67Å; L292-A294 PolarHBondContact O-N 2.93Å
293	R	93.7	Very high	89.6	Confident	146 Å²	146	58.8 Å²	58.8	55%	0.551	29%	0.293	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.2	-17.3	172.3	-72.9	172.1	-175.9	-179.1	-0.4	114	I289 L291 N295	I289-R293 WeakPolarHBondContact O-CG 3.35Å; I289-R293 PolarHBondContact O-N 2.99Å; L291-R293 PolarHBondContact O-N 3.43Å; L291-R293 VanDerWaalsContact O-N 3.17Å; R293-N295 VanDerWaalsContact C-N 3.26Å; R293-N295 VanDerWaalsContact O-CG 3.29Å; R293-N295 PolarHBondContact O-N 3.18Å; R293-N295 PolarHBondContact O-OD1 3.37Å
294	A	93.5	Very high	90.4	Very high	4 Å²	4	59.4 Å²	59.4	3%	0.033	31%	0.307	C	S	.	.			trans	53.4	39.9	174.5	0	0	0	0	0	114.4	N253 I256 R257 L291 L292	N253-A294 HydrophobicContact CB-CB 3.98Å; N253-A294 WeakPolarHBondContact CB-O 3.34Å; N253-A294 VanDerWaalsContact CG-C 3.5Å; N253-A294 VanDerWaalsContact CG-O 3.3Å; N253-A294 WeakPolarHBondContact O-CB 3.49Å; N253-A294 WeakPolarHBondContact OD1-CA 3.11Å; N253-A294 PolarHBondContact OD1-O 2.96Å; I256-A294 HydrophobicContact CB-CB 4.1Å; I256-A294 HydrophobicContact CG2-CB 3.87Å; R257-A294 HydrophobicContact CG-CB 3.79Å; R257-A294 PolarHBondContact NH2-O 3.32Å; L291-A294 PolarHBondContact O-N 3.29Å; L292-A294 PolarHBondContact O-N 2.93Å
295	N	93.4	Very high	91.2	Very high	123 Å²	123	64.2 Å²	64.2	66%	0.658	33%	0.333	S	S	*	.			trans	-120.1	32	-176.3	-70.5	-22.7	0	0	0	112.4	N253 R293	N253-N295 PolarHBondContact OD1-N 3.08Å; R293-N295 VanDerWaalsContact C-N 3.26Å; R293-N295 VanDerWaalsContact O-CG 3.29Å; R293-N295 PolarHBondContact O-N 3.18Å; R293-N295 PolarHBondContact O-OD1 3.37Å
296	R	93	Very high	91.8	Very high	19 Å²	19	63.8 Å²	63.8	7%	0.072	33%	0.333	C	S	.	.			trans	-68.2	140.8	165.8	-175	-177.5	-70.3	-77.8	0.9	109	N253 L333 I334 R336	N253-R296 PolarHBondContact ND2-O 2.91Å; N253-R296 WeakPolarHBondContact OD1-CB 3.44Å; N253-R296 PolarHBondContact OD1-N 2.69Å; R296-L333 PolarHBondContact NH1-O 3.02Å; R296-L333 PolarHBondContact NH2-O 2.99Å; R296-I334 PolarHBondContact NH1-O 2.87Å; R296-I334 PolarHBondContact NH2-O 2.68Å; R296-R336 WeakPolarHBondContact CD-O 3.31Å; R296-R336 WeakPolarHBondContact CG-O 2.94Å; R296-R336 PolarHBondContact NH1-O 3.37Å
297	D	93	Very high	92.3	Very high	60 Å²	60	61.6 Å²	61.6	32%	0.321	32%	0.318	S	S	.	.			trans	-59.8	133.8	171.1	-178.5	7.7	0	0	0	111.3	F299 T335 S337	D297-F299 WeakPolarHBondContact OD1-CB 3.31Å; D297-F299 WeakPolarHBondContact OD1-CD2 3.07Å; D297-F299 PolarHBondContact OD1-N 2.98Å; D297-T335 VanDerWaalsContact CB-O 3.27Å; D297-T335 WeakPolarHBondContact CB-O 3.3Å; D297-T335 PolarHBondContact N-O 3.34Å; D297-S337 WeakPolarHBondContact O-CA 3.36Å; D297-S337 WeakPolarHBondContact O-CB 3.44Å
298	E	89.4	Confident	92.7	Very high	117 Å²	117	66.2 Å²	66.2	55%	0.547	34%	0.339	S	S	.	.			trans	-112.7	3.5	-178.3	-70.5	174.3	164.5	0	0	112.1	N253	N253-E298 WeakPolarHBondContact CB-OE1 3.23Å; N253-E298 VanDerWaalsContact ND2-CD 3.31Å; N253-E298 WeakPolarHBondContact ND2-CG 3.43Å; N253-E298 PolarHBondContact ND2-OE1 3.27Å
299	F	87.8	Confident	93	Very high	148 Å²	148	72.6 Å²	72.6	65%	0.649	36%	0.364	S	S	*	.			trans	-69	134	175.6	-67	-60	0	0	0	112	D297 S337	D297-F299 WeakPolarHBondContact OD1-CB 3.31Å; D297-F299 WeakPolarHBondContact OD1-CD2 3.07Å; D297-F299 PolarHBondContact OD1-N 2.98Å; F299-S337 WeakPolarHBondContact O-CB 3.14Å; F299-S337 PolarHBondContact O-OG 2.84Å; F299-S337 VanDerWaalsContact O-OG 3.06Å
300	T	85.7	Confident	93.3	Very high	111 Å²	111	71.9 Å²	71.9	68%	0.681	36%	0.36	S	S	*	.			trans	-87.9	-8.5	179.6	52.3	0	0	0	0	113.8
301	F	91.2	Very high	93.4	Very high	166 Å²	166	70.5 Å²	70.5	73%	0.728	35%	0.348	S	S	*	.			trans	-78.6	135.9	174.4	178.6	-95.5	0	0	0	110.6	D303	F301-D303 HydrophobicContact CE1-CB 4.22Å
302	I	92.6	Very high	93.4	Very high	70 Å²	70	74.6 Å²	74.6	36%	0.359	37%	0.367	S	S	.	.			trans	-116.8	113.9	-177.4	-57.3	175.1	0	0	0	108.8	G304 V307 A343	I302-G304 PolarHBondContact O-N 2.98Å; I302-V307 HydrophobicContact CG2-CG2 3.5Å; I302-A343 HydrophobicContact CD1-CB 4.48Å; I302-A343 HydrophobicContact CG2-CB 4.08Å
303	D	94.7	Very high	93.2	Very high	50 Å²	50	75.5 Å²	75.5	27%	0.267	37%	0.371	S	S	.	.			trans	-83.8	108.1	171.7	170.6	26.1	0	0	0	110.1	F301 N305 L306 V307 R309	F301-D303 HydrophobicContact CE1-CB 4.22Å; D303-N305 PolarHBondContact O-N 3.32Å; D303-N305 VanDerWaalsContact O-N 3.16Å; D303-N305 WeakPolarHBondContact OD1-CB 3.17Å; D303-N305 PolarHBondContact OD1-N 2.82Å; D303-N305 PolarHBondContact OD1-ND2 3.15Å; D303-L306 HydrophobicContact CB-CB 3.95Å; D303-L306 WeakPolarHBondContact O-CA 3.48Å; D303-L306 WeakPolarHBondContact O-CB 3.35Å; D303-L306 PolarHBondContact O-N 3.48Å; D303-L306 WeakPolarHBondContact OD2-CB 3.26Å; D303-L306 PolarHBondContact OD2-N 3.41Å; D303-L306 VanDerWaalsContact OD2-N 3.17Å; D303-V307 WeakPolarHBondContact O-CG2 3.37Å; D303-V307 PolarHBondContact O-N 2.87Å; D303-R309 IonicContact OD2-NH2 2.8Å
304	G	95.5	Very high	93	Very high	47 Å²	47	68.5 Å²	68.5	49%	0.485	35%	0.345	S	S	.	.	H	α-helix	trans	-55.7	-31.2	177	0	0	0	0	0	113.9	I302 L306 V307 Q308	I302-G304 PolarHBondContact O-N 2.98Å; G304-L306 VanDerWaalsContact C-N 3.3Å; G304-L306 PolarHBondContact O-N 3.04Å; G304-V307 PolarHBondContact O-N 2.64Å; G304-Q308 PolarHBondContact O-N 3.06Å
305	N	96.4	Very high	92.7	Very high	113 Å²	113	70.4 Å²	70.4	60%	0.604	35%	0.354	S	S	*	.	H	α-helix	trans	-71.3	-27.5	176.6	-50.5	-86.9	0	0	0	111.7	D303 R309	D303-N305 PolarHBondContact O-N 3.32Å; D303-N305 VanDerWaalsContact O-N 3.16Å; D303-N305 WeakPolarHBondContact OD1-CB 3.17Å; D303-N305 PolarHBondContact OD1-N 2.82Å; D303-N305 PolarHBondContact OD1-ND2 3.15Å; N305-R309 WeakPolarHBondContact O-CG 3.47Å; N305-R309 PolarHBondContact O-NE 2.74Å
306	L	96.5	Very high	92.3	Very high	40 Å²	40	68.6 Å²	68.6	21%	0.209	34%	0.338	C	S	.	.	H	α-helix	trans	-79.2	-37.5	171.9	-170.5	66.6	0	0	0	111.2	D303 G304 R309 D310	D303-L306 HydrophobicContact CB-CB 3.95Å; D303-L306 WeakPolarHBondContact O-CA 3.48Å; D303-L306 WeakPolarHBondContact O-CB 3.35Å; D303-L306 PolarHBondContact O-N 3.48Å; D303-L306 WeakPolarHBondContact OD2-CB 3.26Å; D303-L306 PolarHBondContact OD2-N 3.41Å; D303-L306 VanDerWaalsContact OD2-N 3.17Å; G304-L306 VanDerWaalsContact C-N 3.3Å; G304-L306 PolarHBondContact O-N 3.04Å; L306-R309 PolarHBondContact O-N 3.46Å; L306-D310 PolarHBondContact O-N 3.23Å
307	V	96.7	Very high	91.9	Very high	5 Å²	5	67.7 Å²	67.7	3%	0.03	34%	0.335	C	S	.	.	H	α-helix	trans	-58.4	-54.3	174.8	179.3	0	0	0	0	109.6	I302 D303 G304 R309 D310 V311 H340 A343 V344 E347	I302-V307 HydrophobicContact CG2-CG2 3.5Å; D303-V307 WeakPolarHBondContact O-CG2 3.37Å; D303-V307 PolarHBondContact O-N 2.87Å; G304-V307 PolarHBondContact O-N 2.64Å; V307-R309 VanDerWaalsContact C-N 3.32Å; V307-R309 PolarHBondContact O-N 3.11Å; V307-D310 PolarHBondContact O-N 2.71Å; V307-D310 VanDerWaalsContact O-N 3.1Å; V307-V311 HydrophobicContact CG1-CG2 4.17Å; V307-V311 VanDerWaalsContact O-CG2 3.26Å; V307-V311 WeakPolarHBondContact O-CG2 3.49Å; V307-V311 PolarHBondContact O-N 3.07Å; V307-H340 PolarHBondContact N-CE1 2.85Å; V307-A343 HydrophobicContact CG1-CB 4.07Å; V307-A343 HydrophobicContact CG2-CB 3.95Å; V307-V344 HydrophobicContact CB-CG2 4.36Å; V307-V344 HydrophobicContact CG1-CB 4.44Å; V307-V344 HydrophobicContact CG1-CG2 3.83Å; V307-E347 VanDerWaalsContact CG1-OE2 3.28Å; V307-E347 WeakPolarHBondContact CG1-OE2 3.39Å
308	Q	96.1	Very high	91.3	Very high	99 Å²	99	65.1 Å²	65.1	46%	0.463	32%	0.321	S	S	.	.	H	α-helix	trans	-54.9	-44.5	179.1	-170	-168	-33.9	0	0	112.4	G304 D310 V311 E312	G304-Q308 PolarHBondContact O-N 3.06Å; Q308-D310 PolarHBondContact O-N 2.94Å; Q308-V311 WeakPolarHBondContact O-CB 3.5Å; Q308-V311 PolarHBondContact O-N 3.46Å; Q308-E312 PolarHBondContact NE2-OE1 2.92Å; Q308-E312 WeakPolarHBondContact O-CG 3.37Å; Q308-E312 PolarHBondContact O-N 3.38Å
309	R	95.8	Very high	90.7	Very high	135 Å²	135	65.1 Å²	65.1	51%	0.509	32%	0.319	S	S	.	.	H	α-helix	trans	-64.9	-38.4	178.2	-76.6	177.9	-70.3	157.8	-2.6	113.3	D303 N305 L306 V307 E313	D303-R309 IonicContact OD2-NH2 2.8Å; N305-R309 WeakPolarHBondContact O-CG 3.47Å; N305-R309 PolarHBondContact O-NE 2.74Å; L306-R309 PolarHBondContact O-N 3.46Å; V307-R309 VanDerWaalsContact C-N 3.32Å; V307-R309 PolarHBondContact O-N 3.11Å; R309-E313 PolarHBondContact O-N 3.36Å; R309-E313 VanDerWaalsContact O-N 3.08Å
310	D	95.4	Very high	89.8	Confident	8 Å²	8	64 Å²	64	4%	0.043	32%	0.316	C	S	.	.	H	α-helix	trans	-74.8	-28.5	176.3	-71	-15	0	0	0	111.7	L306 V307 Q308 L314 I332 R336 H340 V344	L306-D310 PolarHBondContact O-N 3.23Å; V307-D310 PolarHBondContact O-N 2.71Å; V307-D310 VanDerWaalsContact O-N 3.1Å; Q308-D310 PolarHBondContact O-N 2.94Å; D310-L314 WeakPolarHBondContact O-CB 3.47Å; D310-L314 PolarHBondContact O-N 2.92Å; D310-I332 HydrophobicContact CB-CD1 4.4Å; D310-I332 HydrophobicContact CB-CG2 4.06Å; D310-I332 WeakPolarHBondContact OD1-CD1 3.27Å; D310-R336 IonicContact OD1-CZ 2.64Å; D310-R336 IonicContact OD1-NE 3.83Å; D310-R336 IonicContact OD1-NH2 3.7Å; D310-R336 PolarHBondContact OD1-NH2 3.18Å; D310-R336 IonicContact OD2-CZ 2.86Å; D310-R336 IonicContact OD2-NE 3.78Å; D310-R336 PolarHBondContact OD2-NE 2.83Å; D310-R336 IonicContact OD2-NH2 2.8Å; D310-R336 PolarHBondContact OD2-NH2 2.78Å; D310-H340 IonicContact OD2-CD2 2.85Å; D310-H340 IonicContact OD2-CE1 3.65Å; D310-H340 IonicContact OD2-NE2 3.48Å; D310-H340 PolarHBondContact OD2-NE2 3.39Å; D310-V344 HydrophobicContact CB-CG1 4.49Å; D310-V344 HydrophobicContact CB-CG2 3.85Å
311	V	93.9	Very high	88.6	Confident	2 Å²	2	65.9 Å²	65.9	1%	0.012	32%	0.322	C	S	.	.	H	α-helix	trans	-67.3	-44.1	170	171.7	0	0	0	0	111	V307 Q308 E313 L314 I315 V344 E347 L351	V307-V311 HydrophobicContact CG1-CG2 4.17Å; V307-V311 VanDerWaalsContact O-CG2 3.26Å; V307-V311 WeakPolarHBondContact O-CG2 3.49Å; V307-V311 PolarHBondContact O-N 3.07Å; Q308-V311 WeakPolarHBondContact O-CB 3.5Å; Q308-V311 PolarHBondContact O-N 3.46Å; V311-E313 VanDerWaalsContact C-N 3.34Å; V311-E313 PolarHBondContact O-N 3.36Å; V311-L314 PolarHBondContact O-N 3.08Å; V311-I315 HydrophobicContact CG1-CD1 3.89Å; V311-I315 HydrophobicContact CG1-CG1 4.49Å; V311-I315 WeakPolarHBondContact O-CG1 3.45Å; V311-I315 PolarHBondContact O-N 2.91Å; V311-V344 HydrophobicContact CG2-CB 4.13Å; V311-V344 HydrophobicContact CG2-CG1 3.78Å; V311-V344 HydrophobicContact CG2-CG2 4.35Å; V311-V344 WeakPolarHBondContact CG2-O 3.39Å; V311-E347 HydrophobicContact CG1-CG 4.38Å; V311-E347 HydrophobicContact CG2-CB 3.92Å; V311-E347 HydrophobicContact CG2-CG 4.1Å; V311-L351 HydrophobicContact CG1-CD1 3.77Å
312	E	92.1	Very high	87.4	Confident	103 Å²	103	60 Å²	60	48%	0.481	30%	0.297	S	S	.	.	H	α-helix	trans	-59.4	-43.9	173.5	-74.9	169.3	-165.8	0	0	111.2	Q308 I315 R316	Q308-E312 PolarHBondContact NE2-OE1 2.92Å; Q308-E312 WeakPolarHBondContact O-CG 3.37Å; Q308-E312 PolarHBondContact O-N 3.38Å; E312-I315 PolarHBondContact O-N 3.49Å; E312-R316 VanDerWaalsContact O-CB 3.24Å; E312-R316 WeakPolarHBondContact O-CB 3.23Å; E312-R316 PolarHBondContact O-N 3.21Å
313	E	90.9	Very high	86.3	Confident	19 Å²	19	63.4 Å²	63.4	9%	0.089	31%	0.306	C	S	.	.	H	α-helix	trans	-65.3	-36.3	174.9	-177.7	63.7	-161.1	0	0	112.8	R309 V311 R316 A317 K328 I332	R309-E313 PolarHBondContact O-N 3.36Å; R309-E313 VanDerWaalsContact O-N 3.08Å; V311-E313 VanDerWaalsContact C-N 3.34Å; V311-E313 PolarHBondContact O-N 3.36Å; E313-R316 WeakPolarHBondContact O-CB 3.32Å; E313-R316 PolarHBondContact O-N 3.32Å; E313-R316 IonicContact OE1-CZ 3.58Å; E313-R316 IonicContact OE1-NE 2.67Å; E313-R316 IonicContact OE1-NH2 2.75Å; E313-R316 PolarHBondContact OE1-NH2 2.82Å; E313-R316 IonicContact OE2-CZ 3.22Å; E313-R316 IonicContact OE2-NE 2.82Å; E313-R316 PolarHBondContact OE2-NE 3.43Å; E313-R316 IonicContact OE2-NH2 2.81Å; E313-R316 PolarHBondContact OE2-NH2 2.97Å; E313-A317 WeakPolarHBondContact O-CB 3.38Å; E313-A317 PolarHBondContact O-N 2.65Å; E313-K328 HydrophobicContact CG-CB 3.94Å; E313-K328 WeakPolarHBondContact OE1-CB 3.46Å; E313-K328 WeakPolarHBondContact OE1-CG 3.39Å; E313-K328 PolarHBondContact OE1-N 3.18Å; E313-I332 HydrophobicContact CB-CD1 4.09Å; E313-I332 HydrophobicContact CG-CD1 3.7Å
314	L	88.9	Confident	85.1	Confident	0 Å²	0	61.4 Å²	61.4	0%	0	30%	0.295	C	S	.	.	H	α-helix	trans	-66.7	-46.6	174.9	175.7	54.4	0	0	0	111.9	D310 V311 R316 A317 L318 F329 V344 F345 Y348 L356 M360	D310-L314 WeakPolarHBondContact O-CB 3.47Å; D310-L314 PolarHBondContact O-N 2.92Å; V311-L314 PolarHBondContact O-N 3.08Å; L314-R316 VanDerWaalsContact C-N 3.26Å; L314-R316 PolarHBondContact O-N 3.35Å; L314-A317 PolarHBondContact O-N 3.13Å; L314-L318 HydrophobicContact CD1-CD1 3.48Å; L314-L318 VanDerWaalsContact CD1-CD1 3.48Å; L314-L318 HydrophobicContact CD1-CG 3.97Å; L314-L318 HydrophobicContact CG-CD1 4.01Å; L314-L318 WeakPolarHBondContact O-CG 3.29Å; L314-L318 PolarHBondContact O-N 3.17Å; L314-F329 HydrophobicContact CB-CD2 4.29Å; L314-F329 HydrophobicContact CD1-CD1 4.21Å; L314-F329 HydrophobicContact CD1-CD2 3.72Å; L314-F329 HydrophobicContact CD1-CE1 4.1Å; L314-F329 HydrophobicContact CD1-CE2 3.61Å; L314-F329 HydrophobicContact CD1-CG 4.02Å; L314-F329 HydrophobicContact CD1-CZ 3.79Å; L314-F329 HydrophobicContact CD2-CE2 4.27Å; L314-F329 HydrophobicContact CG-CD2 4.49Å; L314-F329 HydrophobicContact CG-CE2 4.35Å; L314-V344 HydrophobicContact CD2-CG1 4.08Å; L314-F345 HydrophobicContact CD2-CD1 4.42Å; L314-Y348 HydrophobicContact CB-CD2 4.43Å; L314-Y348 HydrophobicContact CD2-CD2 3.63Å; L314-Y348 HydrophobicContact CD2-CE2 4.33Å; L314-Y348 HydrophobicContact CD2-CG 3.83Å; L314-Y348 HydrophobicContact CG-CD2 3.66Å; L314-Y348 HydrophobicContact CG-CE2 3.97Å; L314-Y348 HydrophobicContact CG-CG 4.35Å; L314-L356 HydrophobicContact CD1-CD1 4.08Å; L314-L356 HydrophobicContact CD2-CD1 4.04Å; L314-L356 HydrophobicContact CD2-CD2 4.04Å; L314-L356 HydrophobicContact CG-CD1 4.44Å; L314-M360 HydrophobicContact CD1-CE 4Å
315	I	87.3	Confident	83.8	Confident	44 Å²	44	63.2 Å²	63.2	23%	0.226	29%	0.291	C	S	.	.	H	α-helix	trans	-60.4	-39.7	174	-67.8	168.8	0	0	0	110.3	V311 E312 K319 Y348 L351	V311-I315 HydrophobicContact CG1-CD1 3.89Å; V311-I315 HydrophobicContact CG1-CG1 4.49Å; V311-I315 WeakPolarHBondContact O-CG1 3.45Å; V311-I315 PolarHBondContact O-N 2.91Å; E312-I315 PolarHBondContact O-N 3.49Å; I315-K319 HydrophobicContact CG2-CD 4.04Å; I315-K319 HydrophobicContact CG2-CG 4.35Å; I315-K319 WeakPolarHBondContact O-CB 3.44Å; I315-K319 PolarHBondContact O-N 2.88Å; I315-Y348 HydrophobicContact CG1-CD2 3.72Å; I315-Y348 HydrophobicContact CG1-CE2 3.66Å; I315-L351 HydrophobicContact CD1-CD1 4.22Å
316	R	86.4	Confident	82.5	Confident	84 Å²	84	64 Å²	64	32%	0.317	29%	0.291	S	S	.	.	H	α-helix	trans	-62.8	-47.3	176.2	-165.8	174.2	78.4	85.1	0.4	111.8	E312 E313 L314 Q320 I322	E312-R316 VanDerWaalsContact O-CB 3.24Å; E312-R316 WeakPolarHBondContact O-CB 3.23Å; E312-R316 PolarHBondContact O-N 3.21Å; E313-R316 WeakPolarHBondContact O-CB 3.32Å; E313-R316 PolarHBondContact O-N 3.32Å; E313-R316 IonicContact OE1-CZ 3.58Å; E313-R316 IonicContact OE1-NE 2.67Å; E313-R316 IonicContact OE1-NH2 2.75Å; E313-R316 PolarHBondContact OE1-NH2 2.82Å; E313-R316 IonicContact OE2-CZ 3.22Å; E313-R316 IonicContact OE2-NE 2.82Å; E313-R316 PolarHBondContact OE2-NE 3.43Å; E313-R316 IonicContact OE2-NH2 2.81Å; E313-R316 PolarHBondContact OE2-NH2 2.97Å; L314-R316 VanDerWaalsContact C-N 3.26Å; L314-R316 PolarHBondContact O-N 3.35Å; R316-Q320 VanDerWaalsContact O-CB 3.31Å; R316-Q320 WeakPolarHBondContact O-CB 3.34Å; R316-Q320 WeakPolarHBondContact O-CG 3.4Å; R316-Q320 PolarHBondContact O-N 3.49Å; R316-I322 HydrophobicContact CG-CD1 4.16Å
317	A	83.3	Confident	81.6	Confident	1 Å²	1	62.5 Å²	62.5	1%	0.008	28%	0.284	C	S	.	.	H	α-helix	trans	-61.9	-46.3	179.3	0	0	0	0	0	112.4	E313 L314 F329	E313-A317 WeakPolarHBondContact O-CB 3.38Å; E313-A317 PolarHBondContact O-N 2.65Å; L314-A317 PolarHBondContact O-N 3.13Å; A317-F329 HydrophobicContact CB-CB 4.05Å
318	L	80	Confident	81.1	Confident	6 Å²	6	68.6 Å²	68.6	3%	0.031	31%	0.309	C	S	.	.	H	α-helix	trans	-76.3	-52.3	-175.4	-66.3	168.7	0	0	0	112.7	L314 I324 Y348 L356 E359 M360 H363	L314-L318 HydrophobicContact CD1-CD1 3.48Å; L314-L318 VanDerWaalsContact CD1-CD1 3.48Å; L314-L318 HydrophobicContact CD1-CG 3.97Å; L314-L318 HydrophobicContact CG-CD1 4.01Å; L314-L318 WeakPolarHBondContact O-CG 3.29Å; L314-L318 PolarHBondContact O-N 3.17Å; L318-I324 HydrophobicContact CD2-CD1 4.28Å; L318-Y348 HydrophobicContact CD1-CE1 4.49Å; L318-Y348 HydrophobicContact CD1-CE2 3.79Å; L318-Y348 WeakPolarHBondContact CD1-OH 3.27Å; L318-L356 HydrophobicContact CD1-CD1 3.78Å; L318-E359 HydrophobicContact CD1-CG 4.24Å; L318-E359 HydrophobicContact CD2-CG 4.2Å; L318-M360 HydrophobicContact CD1-CE 4.21Å; L318-M360 HydrophobicContact CD2-CE 3.75Å; L318-M360 HydrophobicContact CD2-SD 4.33Å; L318-M360 HydrophobicContact CG-CE 4.37Å; L318-H363 WeakPolarHBondContact CD2-NE2 3.43Å
319	K	77.6	Confident	80.6	Confident	117 Å²	117	63.9 Å²	63.9	51%	0.509	29%	0.288	S	S	.	.	H	α-helix	trans	-82.1	-18.6	-167.9	-60.8	-163.8	-176.7	-175.1	0	115.1	I315 N352	I315-K319 HydrophobicContact CG2-CD 4.04Å; I315-K319 HydrophobicContact CG2-CG 4.35Å; I315-K319 WeakPolarHBondContact O-CB 3.44Å; I315-K319 PolarHBondContact O-N 2.88Å; K319-N352 WeakPolarHBondContact CE-OD1 3.49Å; K319-N352 PolarHBondContact NZ-OD1 2.7Å
320	Q	68.2	Low	80.2	Confident	125 Å²	125	58.4 Å²	58.4	58%	0.584	27%	0.268	S	S	*	.	T	Hydrogen-bonded Turn	trans	-93.8	9.7	-175.5	-58.5	-172.4	-10.2	0	0	113.4	R316 I322	R316-Q320 VanDerWaalsContact O-CB 3.31Å; R316-Q320 WeakPolarHBondContact O-CB 3.34Å; R316-Q320 WeakPolarHBondContact O-CG 3.4Å; R316-Q320 PolarHBondContact O-N 3.49Å; Q320-I322 HydrophobicContact CB-CD1 4.11Å; Q320-I322 HydrophobicContact CB-CG1 4Å; Q320-I322 PolarHBondContact O-N 3.09Å; Q320-I322 VanDerWaalsContact O-N 3.09Å
321	N	61.2	Low	80	Confident	150 Å²	150	61.4 Å²	61.4	80%	0.802	29%	0.288	S	S	*	.			trans	52.9	24.5	-173.8	-68.7	-38.2	0	0	0	113.9	R323	N321-R323 PolarHBondContact O-N 3.41Å
322	I	66.9	Low	79.9	Confident	41 Å²	41	62 Å²	62	21%	0.21	29%	0.291	C	S	.	.			trans	-65.5	130.5	168.1	-59.5	172	0	0	0	106.1	R316 Q320 I324 E326	R316-I322 HydrophobicContact CG-CD1 4.16Å; Q320-I322 HydrophobicContact CB-CD1 4.11Å; Q320-I322 HydrophobicContact CB-CG1 4Å; Q320-I322 PolarHBondContact O-N 3.09Å; Q320-I322 VanDerWaalsContact O-N 3.09Å; I322-I324 PolarHBondContact O-N 3.02Å; I322-E326 HydrophobicContact CG2-CB 4.26Å
323	R	68.3	Low	79.9	Confident	143 Å²	143	57.1 Å²	57.1	54%	0.54	27%	0.268	S	S	.	.			trans	-58.1	128.2	172.5	-71.2	172.1	63.8	-172.6	11.1	107.5	N321 E325 E326 S327	N321-R323 PolarHBondContact O-N 3.41Å; R323-E325 HydrophobicContact CB-CB 4.46Å; R323-E325 IonicContact CZ-OE2 3.94Å; R323-E325 IonicContact NE-OE2 3.84Å; R323-E325 PolarHBondContact NE-OE2 3.48Å; R323-E325 IonicContact NH2-OE1 3.73Å; R323-E325 IonicContact NH2-OE2 3.56Å; R323-E325 PolarHBondContact NH2-OE2 3.48Å; R323-E325 PolarHBondContact O-N 2.74Å; R323-E326 HydrophobicContact CB-CB 4.44Å; R323-E326 HydrophobicContact CB-CG 4.13Å; R323-E326 WeakPolarHBondContact CD-OE1 3.33Å; R323-E326 IonicContact CZ-OE1 2.68Å; R323-E326 IonicContact NE-OE1 3.31Å; R323-E326 IonicContact NH1-OE1 3.12Å; R323-E326 PolarHBondContact NH1-OE1 2.74Å; R323-E326 WeakPolarHBondContact O-CA 3.47Å; R323-E326 WeakPolarHBondContact O-CB 3.11Å; R323-E326 PolarHBondContact O-N 3.06Å; R323-S327 PolarHBondContact O-N 2.96Å
324	I	69.4	Low	79.9	Confident	7 Å²	7	56.8 Å²	56.8	4%	0.036	27%	0.267	C	S	.	.	G	3₁₀ helix	trans	-58.7	-27.4	-174.3	-63	168.1	0	0	0	110.8	L318 I322 E326 S327 F329 I330 H363 L365 I368	L318-I324 HydrophobicContact CD2-CD1 4.28Å; I322-I324 PolarHBondContact O-N 3.02Å; I324-E326 VanDerWaalsContact C-N 3.29Å; I324-E326 PolarHBondContact O-N 2.93Å; I324-S327 WeakPolarHBondContact O-CB 3.36Å; I324-S327 PolarHBondContact O-N 3.36Å; I324-S327 PolarHBondContact O-OG 3.13Å; I324-F329 HydrophobicContact CG2-CD1 4.27Å; I324-I330 HydrophobicContact CG2-CD1 4.09Å; I324-I330 HydrophobicContact CG2-CG1 3.94Å; I324-I330 WeakPolarHBondContact O-CD1 3.47Å; I324-H363 HydrophobicContact CD1-CB 3.95Å; I324-L365 HydrophobicContact CB-CD1 3.99Å; I324-L365 HydrophobicContact CD1-CD1 3.91Å; I324-L365 HydrophobicContact CG1-CD1 4.47Å; I324-L365 HydrophobicContact CG2-CD1 4.37Å; I324-I368 HydrophobicContact CG2-CD1 3.76Å
325	E	68	Low	80.1	Confident	86 Å²	86	59.8 Å²	59.8	40%	0.402	29%	0.286	S	S	.	.	G	3₁₀ helix	trans	-55.2	-33.3	169.2	-44.6	-178.4	94.1	0	0	114.8	L283 R323	L283-E325 HydrophobicContact CD1-CB 4.1Å; L283-E325 HydrophobicContact CD1-CG 3.79Å; L283-E325 HydrophobicContact CD2-CG 3.8Å; L283-E325 HydrophobicContact CG-CG 4.26Å; R323-E325 HydrophobicContact CB-CB 4.46Å; R323-E325 IonicContact CZ-OE2 3.94Å; R323-E325 IonicContact NE-OE2 3.84Å; R323-E325 PolarHBondContact NE-OE2 3.48Å; R323-E325 IonicContact NH2-OE1 3.73Å; R323-E325 IonicContact NH2-OE2 3.56Å; R323-E325 PolarHBondContact NH2-OE2 3.48Å; R323-E325 PolarHBondContact O-N 2.74Å
326	E	69.4	Low	80.5	Confident	130 Å²	130	60.6 Å²	60.6	61%	0.607	29%	0.286	S	S	*	.	G	3₁₀ helix	trans	-98.7	-5	-177.9	-62.4	166.4	-171.9	0	0	111.8	I322 R323 I324	I322-E326 HydrophobicContact CG2-CB 4.26Å; R323-E326 HydrophobicContact CB-CB 4.44Å; R323-E326 HydrophobicContact CB-CG 4.13Å; R323-E326 WeakPolarHBondContact CD-OE1 3.33Å; R323-E326 IonicContact CZ-OE1 2.68Å; R323-E326 IonicContact NE-OE1 3.31Å; R323-E326 IonicContact NH1-OE1 3.12Å; R323-E326 PolarHBondContact NH1-OE1 2.74Å; R323-E326 WeakPolarHBondContact O-CA 3.47Å; R323-E326 WeakPolarHBondContact O-CB 3.11Å; R323-E326 PolarHBondContact O-N 3.06Å; I324-E326 VanDerWaalsContact C-N 3.29Å; I324-E326 PolarHBondContact O-N 2.93Å
327	S	77.8	Confident	80.8	Confident	8 Å²	8	56.8 Å²	56.8	6%	0.056	27%	0.272	C	S	.	.	S	Bend	trans	-87.4	159.3	179.7	80.6	0	0	0	0	112.7	R323 I324 F329	R323-S327 PolarHBondContact O-N 2.96Å; I324-S327 WeakPolarHBondContact O-CB 3.36Å; I324-S327 PolarHBondContact O-N 3.36Å; I324-S327 PolarHBondContact O-OG 3.13Å; S327-F329 PolarHBondContact O-N 3.28Å; S327-F329 WeakPolarHBondContact OG-CB 3.43Å; S327-F329 PolarHBondContact OG-N 2.97Å
328	K	86.2	Confident	81.2	Confident	132 Å²	132	57.9 Å²	57.9	57%	0.574	28%	0.276	S	S	*	.	T	Hydrogen-bonded Turn	trans	-79.3	-3.7	172	-49.1	171.9	-176	168.4	0	112.4	E313 I330 P331 I332	E313-K328 HydrophobicContact CG-CB 3.94Å; E313-K328 WeakPolarHBondContact OE1-CB 3.46Å; E313-K328 WeakPolarHBondContact OE1-CG 3.39Å; E313-K328 PolarHBondContact OE1-N 3.18Å; K328-I330 PolarHBondContact O-N 2.79Å; K328-P331 VanDerWaalsContact O-CD 3.31Å; K328-P331 WeakPolarHBondContact O-CD 3.35Å; K328-I332 HydrophobicContact CB-CD1 4.42Å; K328-I332 WeakPolarHBondContact O-CG1 3.47Å; K328-I332 PolarHBondContact O-N 3.13Å; K328-I332 VanDerWaalsContact O-N 3.12Å
329	F	86.7	Confident	81.8	Confident	1 Å²	1	58 Å²	58	0%	0.004	28%	0.279	C	S	.	.	H	α-helix	trans	-63.7	-38.1	-177.5	177	-115.7	0	0	0	112.5	L314 A317 I324 S327 I332 L333 F345 M360 I368	L314-F329 HydrophobicContact CB-CD2 4.29Å; L314-F329 HydrophobicContact CD1-CD1 4.21Å; L314-F329 HydrophobicContact CD1-CD2 3.72Å; L314-F329 HydrophobicContact CD1-CE1 4.1Å; L314-F329 HydrophobicContact CD1-CE2 3.61Å; L314-F329 HydrophobicContact CD1-CG 4.02Å; L314-F329 HydrophobicContact CD1-CZ 3.79Å; L314-F329 HydrophobicContact CD2-CE2 4.27Å; L314-F329 HydrophobicContact CG-CD2 4.49Å; L314-F329 HydrophobicContact CG-CE2 4.35Å; A317-F329 HydrophobicContact CB-CB 4.05Å; I324-F329 HydrophobicContact CG2-CD1 4.27Å; S327-F329 PolarHBondContact O-N 3.28Å; S327-F329 WeakPolarHBondContact OG-CB 3.43Å; S327-F329 PolarHBondContact OG-N 2.97Å; F329-I332 PolarHBondContact O-N 3.07Å; F329-L333 HydrophobicContact CE1-CB 4.4Å; F329-L333 HydrophobicContact CE1-CD1 4.5Å; F329-L333 HydrophobicContact CE1-CD2 3.88Å; F329-L333 HydrophobicContact CE1-CG 4.5Å; F329-L333 HydrophobicContact CE2-CB 4.23Å; F329-L333 HydrophobicContact CE2-CD1 4.33Å; F329-L333 HydrophobicContact CZ-CB 4.13Å; F329-L333 HydrophobicContact CZ-CD1 3.82Å; F329-L333 HydrophobicContact CZ-CD2 4.05Å; F329-L333 HydrophobicContact CZ-CG 4.22Å; F329-L333 WeakPolarHBondContact O-CB 3.44Å; F329-L333 PolarHBondContact O-N 2.99Å; F329-F345 HydrophobicContact CE2-CE1 4.36Å; F329-F345 HydrophobicContact CZ-CE1 4.37Å; F329-M360 HydrophobicContact CD1-CE 4.06Å; F329-M360 HydrophobicContact CE1-CE 3.29Å; F329-M360 HydrophobicContact CE1-SD 4.38Å; F329-M360 HydrophobicContact CZ-CE 3.81Å; F329-I368 HydrophobicContact CE1-CG2 4.24Å
330	I	86.7	Confident	82.6	Confident	19 Å²	19	52.8 Å²	52.8	10%	0.097	26%	0.256	C	S	.	.	H	α-helix	trans	-61.4	-51.6	176.9	-65.7	173.7	0	0	0	111.5	L283 I287 I324 K328 I332 L333 I334 I368	L283-I330 HydrophobicContact CD1-CD1 3.67Å; I287-I330 HydrophobicContact CD1-CD1 4.34Å; I287-I330 HydrophobicContact CD1-CG2 4.43Å; I287-I330 HydrophobicContact CG1-CG2 3.89Å; I324-I330 HydrophobicContact CG2-CD1 4.09Å; I324-I330 HydrophobicContact CG2-CG1 3.94Å; I324-I330 WeakPolarHBondContact O-CD1 3.47Å; K328-I330 PolarHBondContact O-N 2.79Å; I330-I332 VanDerWaalsContact C-N 3.32Å; I330-I332 PolarHBondContact O-N 3.03Å; I330-L333 PolarHBondContact O-N 3.45Å; I330-I334 HydrophobicContact CG2-CD1 3.74Å; I330-I334 HydrophobicContact CG2-CG1 4.49Å; I330-I334 WeakPolarHBondContact O-CG1 3.5Å; I330-I334 PolarHBondContact O-N 2.89Å; I330-I368 HydrophobicContact CD1-CD1 3.91Å; I330-I368 HydrophobicContact CG1-CD1 3.87Å
331	P	90.6	Very high	83.9	Confident	72 Å²	72	46.8 Å²	46.8	47%	0.468	23%	0.229	S	C	.	.	H	α-helix	trans	-50.6	-46	169.6	-30.7	33.5	0	0	0	114.3	K328 I334 T335	K328-P331 VanDerWaalsContact O-CD 3.31Å; K328-P331 WeakPolarHBondContact O-CD 3.35Å; P331-I334 PolarHBondContact O-N 3.32Å; P331-T335 WeakPolarHBondContact O-CB 3.45Å; P331-T335 WeakPolarHBondContact O-CG2 3.35Å; P331-T335 PolarHBondContact O-N 3.3Å; P331-T335 PolarHBondContact O-OG1 3.37Å
332	I	93.1	Very high	85.4	Confident	13 Å²	13	42.9 Å²	42.9	7%	0.067	20%	0.202	C	C	.	.	H	α-helix	trans	-61.4	-50.4	178.5	-71.1	165.1	0	0	0	110.8	D310 E313 K328 F329 I330 I334 T335 R336 L341	D310-I332 HydrophobicContact CB-CD1 4.4Å; D310-I332 HydrophobicContact CB-CG2 4.06Å; D310-I332 WeakPolarHBondContact OD1-CD1 3.27Å; E313-I332 HydrophobicContact CB-CD1 4.09Å; E313-I332 HydrophobicContact CG-CD1 3.7Å; K328-I332 HydrophobicContact CB-CD1 4.42Å; K328-I332 WeakPolarHBondContact O-CG1 3.47Å; K328-I332 PolarHBondContact O-N 3.13Å; K328-I332 VanDerWaalsContact O-N 3.12Å; F329-I332 PolarHBondContact O-N 3.07Å; I330-I332 VanDerWaalsContact C-N 3.32Å; I330-I332 PolarHBondContact O-N 3.03Å; I332-I334 VanDerWaalsContact C-N 3.26Å; I332-I334 PolarHBondContact O-N 2.79Å; I332-T335 PolarHBondContact O-N 2.9Å; I332-R336 HydrophobicContact CG2-CG 3.86Å; I332-R336 WeakPolarHBondContact O-CB 3.49Å; I332-R336 WeakPolarHBondContact O-CG 3.33Å; I332-R336 PolarHBondContact O-N 3.11Å; I332-L341 HydrophobicContact CG2-CD2 4Å
333	L	91.1	Very high	86.7	Confident	1 Å²	1	42.2 Å²	42.2	1%	0.005	20%	0.203	C	C	.	.	H	α-helix	trans	-60.1	-32.3	-178.4	-176.4	67.3	0	0	0	113.1	R296 F329 I330 L341 F345 I368 I371 V372 I375	R296-L333 PolarHBondContact NH1-O 3.02Å; R296-L333 PolarHBondContact NH2-O 2.99Å; F329-L333 HydrophobicContact CE1-CB 4.4Å; F329-L333 HydrophobicContact CE1-CD1 4.5Å; F329-L333 HydrophobicContact CE1-CD2 3.88Å; F329-L333 HydrophobicContact CE1-CG 4.5Å; F329-L333 HydrophobicContact CE2-CB 4.23Å; F329-L333 HydrophobicContact CE2-CD1 4.33Å; F329-L333 HydrophobicContact CZ-CB 4.13Å; F329-L333 HydrophobicContact CZ-CD1 3.82Å; F329-L333 HydrophobicContact CZ-CD2 4.05Å; F329-L333 HydrophobicContact CZ-CG 4.22Å; F329-L333 WeakPolarHBondContact O-CB 3.44Å; F329-L333 PolarHBondContact O-N 2.99Å; I330-L333 PolarHBondContact O-N 3.45Å; L333-L341 WeakPolarHBondContact O-CD1 3.08Å; L333-F345 HydrophobicContact CD1-CE1 4.34Å; L333-F345 HydrophobicContact CD1-CZ 3.69Å; L333-I368 HydrophobicContact CD2-CB 4.48Å; L333-I368 HydrophobicContact CD2-CG1 4.47Å; L333-I368 HydrophobicContact CD2-CG2 3.82Å; L333-I371 HydrophobicContact CD1-CG2 3.91Å; L333-I371 HydrophobicContact CD2-CB 4.22Å; L333-I371 HydrophobicContact CD2-CG2 3.95Å; L333-I371 HydrophobicContact CG-CB 4.47Å; L333-I371 HydrophobicContact CG-CG2 3.66Å; L333-V372 HydrophobicContact CD1-CG2 3.99Å; L333-V372 HydrophobicContact CD2-CG2 4.42Å; L333-I375 HydrophobicContact CD1-CD1 3.48Å; L333-I375 VanDerWaalsContact CD1-CD1 3.48Å; L333-I375 HydrophobicContact CG-CD1 4.38Å
334	I	91.9	Very high	88	Confident	12 Å²	12	35.4 Å²	35.4	6%	0.062	18%	0.177	C	C	.	.	H	α-helix	trans	-86.8	-37.3	179	-63.1	174.5	0	0	0	111.9	I287 A290 L291 R296 I330 P331 I332	I287-I334 HydrophobicContact CB-CD1 4.34Å; I287-I334 HydrophobicContact CG1-CD1 4.36Å; I287-I334 HydrophobicContact CG2-CD1 3.98Å; A290-I334 HydrophobicContact CB-CD1 3.82Å; A290-I334 HydrophobicContact CB-CG2 4.06Å; L291-I334 HydrophobicContact CD2-CG2 4.18Å; L291-I334 HydrophobicContact CG-CG2 4.46Å; R296-I334 PolarHBondContact NH1-O 2.87Å; R296-I334 PolarHBondContact NH2-O 2.68Å; I330-I334 HydrophobicContact CG2-CD1 3.74Å; I330-I334 HydrophobicContact CG2-CG1 4.49Å; I330-I334 WeakPolarHBondContact O-CG1 3.5Å; I330-I334 PolarHBondContact O-N 2.89Å; P331-I334 PolarHBondContact O-N 3.32Å; I332-I334 VanDerWaalsContact C-N 3.26Å; I332-I334 PolarHBondContact O-N 2.79Å
335	T	93.1	Very high	89.1	Confident	64 Å²	64	35.1 Å²	35.1	39%	0.393	18%	0.176	S	C	.	.	H	α-helix	trans	-97	-28.5	-169.3	60.6	0	0	0	0	115.6	D297 P331 I332	D297-T335 VanDerWaalsContact CB-O 3.27Å; D297-T335 WeakPolarHBondContact CB-O 3.3Å; D297-T335 PolarHBondContact N-O 3.34Å; P331-T335 WeakPolarHBondContact O-CB 3.45Å; P331-T335 WeakPolarHBondContact O-CG2 3.35Å; P331-T335 PolarHBondContact O-N 3.3Å; P331-T335 PolarHBondContact O-OG1 3.37Å; I332-T335 PolarHBondContact O-N 2.9Å
336	R	94.6	Very high	90.3	Very high	61 Å²	61	36.2 Å²	36.2	23%	0.23	19%	0.185	C	C	.	.	S	Bend	trans	-72.8	156.5	179.9	-66.2	-66.4	-166.5	-113.5	-16.3	112.7	R296 D310 I332 L341	R296-R336 WeakPolarHBondContact CD-O 3.31Å; R296-R336 WeakPolarHBondContact CG-O 2.94Å; R296-R336 PolarHBondContact NH1-O 3.37Å; D310-R336 IonicContact OD1-CZ 2.64Å; D310-R336 IonicContact OD1-NE 3.83Å; D310-R336 IonicContact OD1-NH2 3.7Å; D310-R336 PolarHBondContact OD1-NH2 3.18Å; D310-R336 IonicContact OD2-CZ 2.86Å; D310-R336 IonicContact OD2-NE 3.78Å; D310-R336 PolarHBondContact OD2-NE 2.83Å; D310-R336 IonicContact OD2-NH2 2.8Å; D310-R336 PolarHBondContact OD2-NH2 2.78Å; I332-R336 HydrophobicContact CG2-CG 3.86Å; I332-R336 WeakPolarHBondContact O-CB 3.49Å; I332-R336 WeakPolarHBondContact O-CG 3.33Å; I332-R336 PolarHBondContact O-N 3.11Å; R336-L341 HydrophobicContact CB-CD1 3.93Å; R336-L341 HydrophobicContact CB-CD2 3.85Å; R336-L341 HydrophobicContact CB-CG 3.64Å; R336-L341 HydrophobicContact CG-CD2 4.29Å
337	S	93.2	Very high	91.5	Very high	4 Å²	4	33 Å²	33	3%	0.028	17%	0.17	C	C	.	.			trans	-67.2	154.6	177.6	78	0	0	0	0	112.1	D297 F299 G339 H340 L341	D297-S337 WeakPolarHBondContact O-CA 3.36Å; D297-S337 WeakPolarHBondContact O-CB 3.44Å; F299-S337 WeakPolarHBondContact O-CB 3.14Å; F299-S337 PolarHBondContact O-OG 2.84Å; F299-S337 VanDerWaalsContact O-OG 3.06Å; S337-G339 VanDerWaalsContact C-N 3.34Å; S337-G339 PolarHBondContact O-N 3.19Å; S337-H340 PolarHBondContact O-N 3.45Å; S337-H340 WeakPolarHBondContact OG-CB 3.41Å; S337-H340 PolarHBondContact OG-N 3.3Å; S337-L341 PolarHBondContact O-N 3.27Å
338	Y	91.8	Very high	92.1	Very high	23 Å²	23	32.6 Å²	32.6	9%	0.09	17%	0.167	C	C	.	.	H	α-helix	trans	-60.9	-42.3	-178.8	-71.4	-73.9	0	0	0	111.9	E136 L341 R342 I375	E136-Y338 WeakPolarHBondContact OE1-CB 3.35Å; Y338-L341 PolarHBondContact O-N 3.31Å; Y338-R342 WeakPolarHBondContact O-CG 3.41Å; Y338-R342 PolarHBondContact O-N 3.42Å; Y338-I375 HydrophobicContact CD1-CB 4.25Å; Y338-I375 HydrophobicContact CD1-CG1 3.73Å; Y338-I375 HydrophobicContact CD1-CG2 4.39Å; Y338-I375 HydrophobicContact CE1-CG1 3.86Å
339	G	91.7	Very high	92.3	Very high	10 Å²	10	28 Å²	28	10%	0.103	15%	0.151	C	C	.	.	H	α-helix	trans	-58.4	-46.1	172.3	0	0	0	0	0	113.6	E136 S337 R342 A343	E136-G339 PolarHBondContact OE2-N 3.42Å; S337-G339 VanDerWaalsContact C-N 3.34Å; S337-G339 PolarHBondContact O-N 3.19Å; G339-R342 PolarHBondContact O-N 2.98Å; G339-A343 PolarHBondContact O-N 3.36Å; G339-A343 VanDerWaalsContact O-N 3.12Å
340	H	95	Very high	92.5	Very high	6 Å²	6	32.5 Å²	32.5	3%	0.028	18%	0.183	C	C	.	.	H	α-helix	trans	-61.4	-46.8	176.4	-179.7	89.3	0	0	0	112.2	V307 D310 S337 R342 A343 V344	V307-H340 PolarHBondContact N-CE1 2.85Å; D310-H340 IonicContact OD2-CD2 2.85Å; D310-H340 IonicContact OD2-CE1 3.65Å; D310-H340 IonicContact OD2-NE2 3.48Å; D310-H340 PolarHBondContact OD2-NE2 3.39Å; S337-H340 PolarHBondContact O-N 3.45Å; S337-H340 WeakPolarHBondContact OG-CB 3.41Å; S337-H340 PolarHBondContact OG-N 3.3Å; H340-R342 PolarHBondContact O-N 3.41Å; H340-A343 WeakPolarHBondContact O-CB 3.27Å; H340-A343 PolarHBondContact O-N 2.84Å; H340-A343 VanDerWaalsContact O-N 3.12Å; H340-V344 WeakPolarHBondContact O-CG2 3.32Å; H340-V344 PolarHBondContact O-N 3.4Å
341	L	94.7	Very high	92.7	Very high	0 Å²	0	36.6 Å²	36.6	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-67.8	-35	-179.3	-69.9	168.3	0	0	0	112.5	I332 L333 R336 S337 Y338 A343 V344 F345 I375	I332-L341 HydrophobicContact CG2-CD2 4Å; L333-L341 WeakPolarHBondContact O-CD1 3.08Å; R336-L341 HydrophobicContact CB-CD1 3.93Å; R336-L341 HydrophobicContact CB-CD2 3.85Å; R336-L341 HydrophobicContact CB-CG 3.64Å; R336-L341 HydrophobicContact CG-CD2 4.29Å; S337-L341 PolarHBondContact O-N 3.27Å; Y338-L341 PolarHBondContact O-N 3.31Å; L341-A343 VanDerWaalsContact C-N 3.31Å; L341-A343 PolarHBondContact O-N 3.42Å; L341-V344 PolarHBondContact O-N 2.83Å; L341-F345 HydrophobicContact CB-CE2 4.46Å; L341-F345 HydrophobicContact CB-CZ 4.2Å; L341-F345 HydrophobicContact CD2-CE1 4.5Å; L341-F345 VanDerWaalsContact O-CD1 3.26Å; L341-F345 WeakPolarHBondContact O-CD1 3.43Å; L341-F345 WeakPolarHBondContact O-CD2 3.41Å; L341-F345 WeakPolarHBondContact O-CG 3.49Å; L341-F345 PolarHBondContact O-N 2.69Å; L341-I375 HydrophobicContact CB-CD1 4.42Å; L341-I375 HydrophobicContact CB-CG2 3.67Å; L341-I375 HydrophobicContact CD1-CD1 3.75Å; L341-I375 HydrophobicContact CD1-CG1 4.48Å
342	R	93.6	Very high	92.4	Very high	67 Å²	67	34.7 Å²	34.7	25%	0.253	19%	0.19	S	C	.	.	H	α-helix	trans	-62.2	-37.6	170	-73.9	-169.5	-59.7	-88.3	-6.2	112.1	E136 Y338 G339 H340 F345 N346 I375	E136-R342 IonicContact OE1-CZ 2.77Å; E136-R342 IonicContact OE1-NH1 2.6Å; E136-R342 PolarHBondContact OE1-NH1 3.17Å; E136-R342 IonicContact OE1-NH2 2.9Å; E136-R342 PolarHBondContact OE1-NH2 2.95Å; E136-R342 IonicContact OE2-CZ 2.73Å; E136-R342 IonicContact OE2-NH1 3.66Å; E136-R342 IonicContact OE2-NH2 2.68Å; E136-R342 PolarHBondContact OE2-NH2 3.48Å; Y338-R342 WeakPolarHBondContact O-CG 3.41Å; Y338-R342 PolarHBondContact O-N 3.42Å; G339-R342 PolarHBondContact O-N 2.98Å; H340-R342 PolarHBondContact O-N 3.41Å; R342-F345 PolarHBondContact O-N 2.89Å; R342-N346 WeakPolarHBondContact O-CB 3.3Å; R342-N346 PolarHBondContact O-N 3.24Å; R342-N346 PolarHBondContact O-ND2 2.93Å; R342-N346 PolarHBondContact O-OD1 3.45Å; R342-I375 VanDerWaalsContact CD-O 3.29Å; R342-I375 WeakPolarHBondContact CD-O 3.44Å; R342-I375 HydrophobicContact CG-CG2 3.98Å; R342-I375 VanDerWaalsContact CG-O 3.27Å; R342-I375 WeakPolarHBondContact CG-O 3.46Å
343	A	94.2	Very high	91.8	Very high	27 Å²	27	43.5 Å²	43.5	22%	0.223	23%	0.228	C	C	.	.	H	α-helix	trans	-63.3	-47.3	173	0	0	0	0	0	111.8	I302 V307 G339 H340 L341 F345 N346 E347	I302-A343 HydrophobicContact CD1-CB 4.48Å; I302-A343 HydrophobicContact CG2-CB 4.08Å; V307-A343 HydrophobicContact CG1-CB 4.07Å; V307-A343 HydrophobicContact CG2-CB 3.95Å; G339-A343 PolarHBondContact O-N 3.36Å; G339-A343 VanDerWaalsContact O-N 3.12Å; H340-A343 WeakPolarHBondContact O-CB 3.27Å; H340-A343 PolarHBondContact O-N 2.84Å; H340-A343 VanDerWaalsContact O-N 3.12Å; L341-A343 VanDerWaalsContact C-N 3.31Å; L341-A343 PolarHBondContact O-N 3.42Å; A343-F345 VanDerWaalsContact C-N 3.31Å; A343-F345 PolarHBondContact O-N 3.37Å; A343-N346 PolarHBondContact O-N 2.89Å; A343-E347 PolarHBondContact O-N 3Å
344	V	94.9	Very high	91.2	Very high	0 Å²	0	45 Å²	45	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-55.5	-44.1	175	170.8	0	0	0	0	111.4	V307 D310 V311 L314 H340 L341 Y348	V307-V344 HydrophobicContact CB-CG2 4.36Å; V307-V344 HydrophobicContact CG1-CB 4.44Å; V307-V344 HydrophobicContact CG1-CG2 3.83Å; D310-V344 HydrophobicContact CB-CG1 4.49Å; D310-V344 HydrophobicContact CB-CG2 3.85Å; V311-V344 HydrophobicContact CG2-CB 4.13Å; V311-V344 HydrophobicContact CG2-CG1 3.78Å; V311-V344 HydrophobicContact CG2-CG2 4.35Å; V311-V344 WeakPolarHBondContact CG2-O 3.39Å; L314-V344 HydrophobicContact CD2-CG1 4.08Å; H340-V344 WeakPolarHBondContact O-CG2 3.32Å; H340-V344 PolarHBondContact O-N 3.4Å; L341-V344 PolarHBondContact O-N 2.83Å; V344-Y348 VanDerWaalsContact O-CB 3.27Å; V344-Y348 WeakPolarHBondContact O-CB 3.39Å; V344-Y348 PolarHBondContact O-N 3.3Å
345	F	93.5	Very high	90.7	Very high	1 Å²	1	46.8 Å²	46.8	0%	0.004	25%	0.248	C	C	.	.	H	α-helix	trans	-71.2	-36.1	-178.8	-58.5	-14.2	0	0	0	112.7	L314 F329 L333 L341 R342 A343 S349 L356 V372 I375 Q376	L314-F345 HydrophobicContact CD2-CD1 4.42Å; F329-F345 HydrophobicContact CE2-CE1 4.36Å; F329-F345 HydrophobicContact CZ-CE1 4.37Å; L333-F345 HydrophobicContact CD1-CE1 4.34Å; L333-F345 HydrophobicContact CD1-CZ 3.69Å; L341-F345 HydrophobicContact CB-CE2 4.46Å; L341-F345 HydrophobicContact CB-CZ 4.2Å; L341-F345 HydrophobicContact CD2-CE1 4.5Å; L341-F345 VanDerWaalsContact O-CD1 3.26Å; L341-F345 WeakPolarHBondContact O-CD1 3.43Å; L341-F345 WeakPolarHBondContact O-CD2 3.41Å; L341-F345 WeakPolarHBondContact O-CG 3.49Å; L341-F345 PolarHBondContact O-N 2.69Å; R342-F345 PolarHBondContact O-N 2.89Å; A343-F345 VanDerWaalsContact C-N 3.31Å; A343-F345 PolarHBondContact O-N 3.37Å; F345-S349 WeakPolarHBondContact O-CB 3.28Å; F345-S349 PolarHBondContact O-N 2.89Å; F345-S349 PolarHBondContact O-OG 3.09Å; F345-L356 HydrophobicContact CB-CD2 4.18Å; F345-L356 HydrophobicContact CD1-CD2 3.2Å; F345-L356 HydrophobicContact CD2-CD2 4.19Å; F345-L356 HydrophobicContact CE1-CD2 3.5Å; F345-L356 VanDerWaalsContact CE1-CD2 3.5Å; F345-L356 HydrophobicContact CE2-CD2 4.4Å; F345-L356 HydrophobicContact CG-CD2 3.6Å; F345-L356 HydrophobicContact CZ-CD2 4.09Å; F345-V372 HydrophobicContact CD2-CG1 4.47Å; F345-V372 HydrophobicContact CE2-CB 4.43Å; F345-V372 HydrophobicContact CE2-CG1 4.05Å; F345-V372 HydrophobicContact CE2-CG2 4.4Å; F345-V372 HydrophobicContact CZ-CG1 4.42Å; F345-V372 HydrophobicContact CZ-CG2 4.04Å; F345-I375 HydrophobicContact CD2-CG2 4.16Å; F345-I375 HydrophobicContact CE2-CB 3.88Å; F345-I375 HydrophobicContact CE2-CD1 4.17Å; F345-I375 HydrophobicContact CE2-CG2 3.54Å; F345-I375 HydrophobicContact CZ-CD1 4.07Å; F345-I375 HydrophobicContact CZ-CG2 4.28Å; F345-Q376 HydrophobicContact CD2-CG 3.67Å; F345-Q376 HydrophobicContact CE2-CG 4.22Å
346	N	92.7	Very high	90.2	Very high	109 Å²	109	43.8 Å²	43.8	58%	0.583	23%	0.23	S	C	*	.	H	α-helix	trans	-67.4	-42.6	176	-70.8	-13.3	0	0	0	111.5	R342 A343 S349 S350	R342-N346 WeakPolarHBondContact O-CB 3.3Å; R342-N346 PolarHBondContact O-N 3.24Å; R342-N346 PolarHBondContact O-ND2 2.93Å; R342-N346 PolarHBondContact O-OD1 3.45Å; A343-N346 PolarHBondContact O-N 2.89Å; N346-S349 PolarHBondContact O-N 3.45Å; N346-S350 WeakPolarHBondContact O-CB 3.32Å; N346-S350 PolarHBondContact O-N 3.34Å; N346-S350 PolarHBondContact O-OG 3.15Å
347	E	93.6	Very high	89.6	Confident	63 Å²	63	42.3 Å²	42.3	29%	0.294	23%	0.225	S	C	.	.	H	α-helix	trans	-67.8	-45.2	176.1	-172.8	177.3	154.9	0	0	111.5	V307 V311 A343 S349 S350 L351	V307-E347 VanDerWaalsContact CG1-OE2 3.28Å; V307-E347 WeakPolarHBondContact CG1-OE2 3.39Å; V311-E347 HydrophobicContact CG1-CG 4.38Å; V311-E347 HydrophobicContact CG2-CB 3.92Å; V311-E347 HydrophobicContact CG2-CG 4.1Å; A343-E347 PolarHBondContact O-N 3Å; E347-S349 VanDerWaalsContact C-N 3.32Å; E347-S349 PolarHBondContact O-N 2.89Å; E347-S350 WeakPolarHBondContact O-CB 3.31Å; E347-S350 PolarHBondContact O-N 2.87Å; E347-S350 VanDerWaalsContact O-N 3.15Å; E347-L351 HydrophobicContact CG-CD1 4.15Å; E347-L351 WeakPolarHBondContact O-CG 3.24Å; E347-L351 PolarHBondContact O-N 3.22Å
348	Y	91.9	Very high	88.9	Confident	0 Å²	0	48 Å²	48	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-53.5	-48.4	172.7	178.8	-86	0	0	0	111.8	L314 I315 L318 V344 S350 L351 N352 L356	L314-Y348 HydrophobicContact CB-CD2 4.43Å; L314-Y348 HydrophobicContact CD2-CD2 3.63Å; L314-Y348 HydrophobicContact CD2-CE2 4.33Å; L314-Y348 HydrophobicContact CD2-CG 3.83Å; L314-Y348 HydrophobicContact CG-CD2 3.66Å; L314-Y348 HydrophobicContact CG-CE2 3.97Å; L314-Y348 HydrophobicContact CG-CG 4.35Å; I315-Y348 HydrophobicContact CG1-CD2 3.72Å; I315-Y348 HydrophobicContact CG1-CE2 3.66Å; L318-Y348 HydrophobicContact CD1-CE1 4.49Å; L318-Y348 HydrophobicContact CD1-CE2 3.79Å; L318-Y348 WeakPolarHBondContact CD1-OH 3.27Å; V344-Y348 VanDerWaalsContact O-CB 3.27Å; V344-Y348 WeakPolarHBondContact O-CB 3.39Å; V344-Y348 PolarHBondContact O-N 3.3Å; Y348-S350 VanDerWaalsContact C-N 3.32Å; Y348-S350 PolarHBondContact O-N 2.99Å; Y348-L351 PolarHBondContact O-N 3.47Å; Y348-N352 VanDerWaalsContact CD2-ND2 3.31Å; Y348-N352 WeakPolarHBondContact CD2-ND2 3.38Å; Y348-N352 HydrophobicContact CE1-CB 4.14Å; Y348-N352 VanDerWaalsContact CE2-ND2 3.27Å; Y348-N352 WeakPolarHBondContact CE2-ND2 3.29Å; Y348-N352 WeakPolarHBondContact O-CB 3.5Å; Y348-N352 PolarHBondContact O-N 2.92Å; Y348-N352 PolarHBondContact O-ND2 3.18Å; Y348-L356 HydrophobicContact CD1-CB 4.21Å; Y348-L356 HydrophobicContact CD1-CD1 4.15Å; Y348-L356 HydrophobicContact CE1-CB 4.46Å; Y348-L356 HydrophobicContact CE1-CD1 4.04Å
349	S	90.6	Very high	88.3	Confident	35 Å²	35	49.9 Å²	49.9	25%	0.245	26%	0.261	C	S	.	.	H	α-helix	trans	-65.3	-37.3	-179.2	-53.8	0	0	0	0	111.5	F345 N346 E347 K353	F345-S349 WeakPolarHBondContact O-CB 3.28Å; F345-S349 PolarHBondContact O-N 2.89Å; F345-S349 PolarHBondContact O-OG 3.09Å; N346-S349 PolarHBondContact O-N 3.45Å; E347-S349 VanDerWaalsContact C-N 3.32Å; E347-S349 PolarHBondContact O-N 2.89Å; S349-K353 WeakPolarHBondContact O-CA 3.33Å; S349-K353 PolarHBondContact O-N 2.98Å
350	S	90.5	Very high	87.6	Confident	96 Å²	96	49.5 Å²	49.5	67%	0.671	26%	0.257	S	S	*	.	H	α-helix	trans	-65.9	-39.6	177.1	-58.7	0	0	0	0	112.8	N346 E347 Y348	N346-S350 WeakPolarHBondContact O-CB 3.32Å; N346-S350 PolarHBondContact O-N 3.34Å; N346-S350 PolarHBondContact O-OG 3.15Å; E347-S350 WeakPolarHBondContact O-CB 3.31Å; E347-S350 PolarHBondContact O-N 2.87Å; E347-S350 VanDerWaalsContact O-N 3.15Å; Y348-S350 VanDerWaalsContact C-N 3.32Å; Y348-S350 PolarHBondContact O-N 2.99Å
351	L	90	Very high	86.7	Confident	105 Å²	105	51.8 Å²	51.8	55%	0.55	27%	0.274	S	S	.	.	H	α-helix	trans	-74.8	-39.5	178.3	-68.6	172.2	0	0	0	112.8	V311 I315 E347 Y348	V311-L351 HydrophobicContact CG1-CD1 3.77Å; I315-L351 HydrophobicContact CD1-CD1 4.22Å; E347-L351 HydrophobicContact CG-CD1 4.15Å; E347-L351 WeakPolarHBondContact O-CG 3.24Å; E347-L351 PolarHBondContact O-N 3.22Å; Y348-L351 PolarHBondContact O-N 3.47Å
352	N	84.8	Confident	85.1	Confident	32 Å²	32	55.2 Å²	55.2	17%	0.171	31%	0.308	C	S	.	.	H	α-helix	trans	-98.9	-18.8	-168.8	-64.6	-72.9	0	0	0	114.6	K319 Y348 C354	K319-N352 WeakPolarHBondContact CE-OD1 3.49Å; K319-N352 PolarHBondContact NZ-OD1 2.7Å; Y348-N352 VanDerWaalsContact CD2-ND2 3.31Å; Y348-N352 WeakPolarHBondContact CD2-ND2 3.38Å; Y348-N352 HydrophobicContact CE1-CB 4.14Å; Y348-N352 VanDerWaalsContact CE2-ND2 3.27Å; Y348-N352 WeakPolarHBondContact CE2-ND2 3.29Å; Y348-N352 WeakPolarHBondContact O-CB 3.5Å; Y348-N352 PolarHBondContact O-N 2.92Å; Y348-N352 PolarHBondContact O-ND2 3.18Å; N352-C354 PolarHBondContact O-N 3.35Å
353	K	79.9	Confident	83.8	Confident	197 Å²	197	55.7 Å²	55.7	86%	0.857	31%	0.313	S	S	*	.	S	Bend	trans	61.1	16.8	-176.8	-51.2	179.9	-178.5	178.2	0	115.2	S349	S349-K353 WeakPolarHBondContact O-CA 3.33Å; S349-K353 PolarHBondContact O-N 2.98Å
354	C	79.7	Confident	82.2	Confident	33 Å²	33	56.8 Å²	56.8	22%	0.223	33%	0.328	C	S	.	.	S	Bend	trans	-115.4	155.3	166.9	61.4	0	0	0	0	110.2	N352 E359	N352-C354 PolarHBondContact O-N 3.35Å; C354-E359 PolarHBondContact SG-OE2 2.91Å
355	N	80.3	Confident	81.2	Confident	50 Å²	50	59 Å²	59	27%	0.267	34%	0.34	S	S	.	.			trans	-79.4	131.3	170.2	177.9	4.3	0	0	0	109	E357 E358 E359	N355-E357 WeakPolarHBondContact ND2-CB 3.32Å; N355-E357 PolarHBondContact ND2-OE2 3.41Å; N355-E357 PolarHBondContact O-N 3.34Å; N355-E357 VanDerWaalsContact O-N 3.12Å; N355-E357 WeakPolarHBondContact OD1-CB 3.26Å; N355-E357 PolarHBondContact OD1-N 2.93Å; N355-E358 HydrophobicContact CB-CG 3.96Å; N355-E358 WeakPolarHBondContact CB-OE2 3.46Å; N355-E358 PolarHBondContact N-OE2 3.08Å; N355-E358 VanDerWaalsContact N-OE2 3.16Å; N355-E358 WeakPolarHBondContact O-CB 3.4Å; N355-E358 PolarHBondContact O-N 2.91Å; N355-E359 PolarHBondContact O-N 3.14Å
356	L	83.9	Confident	80.6	Confident	0 Å²	0	64.2 Å²	64.2	0%	0	37%	0.367	C	S	.	.	H	α-helix	trans	-54.2	-31.9	175.2	-177.2	61.8	0	0	0	112.9	L314 L318 F345 Y348 E358 M360 V372	L314-L356 HydrophobicContact CD1-CD1 4.08Å; L314-L356 HydrophobicContact CD2-CD1 4.04Å; L314-L356 HydrophobicContact CD2-CD2 4.04Å; L314-L356 HydrophobicContact CG-CD1 4.44Å; L318-L356 HydrophobicContact CD1-CD1 3.78Å; F345-L356 HydrophobicContact CB-CD2 4.18Å; F345-L356 HydrophobicContact CD1-CD2 3.2Å; F345-L356 HydrophobicContact CD2-CD2 4.19Å; F345-L356 HydrophobicContact CE1-CD2 3.5Å; F345-L356 VanDerWaalsContact CE1-CD2 3.5Å; F345-L356 HydrophobicContact CE2-CD2 4.4Å; F345-L356 HydrophobicContact CG-CD2 3.6Å; F345-L356 HydrophobicContact CZ-CD2 4.09Å; Y348-L356 HydrophobicContact CD1-CB 4.21Å; Y348-L356 HydrophobicContact CD1-CD1 4.15Å; Y348-L356 HydrophobicContact CE1-CB 4.46Å; Y348-L356 HydrophobicContact CE1-CD1 4.04Å; L356-E358 VanDerWaalsContact C-N 3.33Å; L356-E358 PolarHBondContact O-N 2.95Å; L356-M360 HydrophobicContact CD1-CE 3.69Å; L356-M360 HydrophobicContact CD1-CG 4.14Å; L356-M360 HydrophobicContact CG-CE 4.37Å; L356-M360 HydrophobicContact CG-CG 4.2Å; L356-M360 VanDerWaalsContact O-CB 3.3Å; L356-M360 WeakPolarHBondContact O-CB 3.47Å; L356-M360 WeakPolarHBondContact O-CG 3.42Å; L356-M360 PolarHBondContact O-N 3.49Å; L356-V372 HydrophobicContact CD2-CG1 3.98Å; L356-V372 HydrophobicContact CD2-CG2 4.4Å; L356-V372 HydrophobicContact CG-CG1 4.16Å
357	E	81.6	Confident	80.1	Confident	30 Å²	30	59.8 Å²	59.8	14%	0.14	34%	0.344	C	S	.	.	H	α-helix	trans	-63.6	-35.3	176.1	-167.2	-166	158.2	0	0	113	N355 S361 L369 R373	N355-E357 WeakPolarHBondContact ND2-CB 3.32Å; N355-E357 PolarHBondContact ND2-OE2 3.41Å; N355-E357 PolarHBondContact O-N 3.34Å; N355-E357 VanDerWaalsContact O-N 3.12Å; N355-E357 WeakPolarHBondContact OD1-CB 3.26Å; N355-E357 PolarHBondContact OD1-N 2.93Å; E357-S361 WeakPolarHBondContact O-CB 3.13Å; E357-S361 PolarHBondContact O-N 3.23Å; E357-S361 PolarHBondContact O-OG 2.95Å; E357-L369 HydrophobicContact CG-CD1 3.76Å; E357-L369 WeakPolarHBondContact O-CD1 3.37Å; E357-R373 HydrophobicContact CG-CG 4.06Å; E357-R373 IonicContact OE1-CZ 3.84Å; E357-R373 IonicContact OE1-NE 3.74Å; E357-R373 PolarHBondContact OE1-NE 3.45Å; E357-R373 IonicContact OE1-NH2 3.34Å; E357-R373 PolarHBondContact OE1-NH2 2.92Å
358	E	78.9	Confident	79.8	Confident	125 Å²	125	56.8 Å²	56.8	58%	0.584	33%	0.33	S	S	*	.	H	α-helix	trans	-71.6	-47.2	179	-64.4	167.8	151.9	0	0	109.9	N355 L356 M360 S361 G362	N355-E358 HydrophobicContact CB-CG 3.96Å; N355-E358 WeakPolarHBondContact CB-OE2 3.46Å; N355-E358 PolarHBondContact N-OE2 3.08Å; N355-E358 VanDerWaalsContact N-OE2 3.16Å; N355-E358 WeakPolarHBondContact O-CB 3.4Å; N355-E358 PolarHBondContact O-N 2.91Å; L356-E358 VanDerWaalsContact C-N 3.33Å; L356-E358 PolarHBondContact O-N 2.95Å; E358-M360 PolarHBondContact O-N 3.34Å; E358-S361 WeakPolarHBondContact O-CB 3.2Å; E358-S361 PolarHBondContact O-N 3.17Å; E358-G362 PolarHBondContact O-N 2.83Å; E358-G362 VanDerWaalsContact O-N 3.09Å
359	E	78.1	Confident	79.6	Confident	61 Å²	61	57.2 Å²	57.2	29%	0.285	33%	0.332	S	S	.	.	H	α-helix	trans	-58.7	-49.2	175.6	-152.1	97.3	166.2	0	0	111	L318 C354 N355 S361 G362 H363	L318-E359 HydrophobicContact CD1-CG 4.24Å; L318-E359 HydrophobicContact CD2-CG 4.2Å; C354-E359 PolarHBondContact SG-OE2 2.91Å; N355-E359 PolarHBondContact O-N 3.14Å; E359-S361 VanDerWaalsContact C-N 3.27Å; E359-S361 PolarHBondContact O-N 3.25Å; E359-G362 WeakPolarHBondContact O-CA 3.29Å; E359-G362 PolarHBondContact O-N 3.35Å; E359-H363 PolarHBondContact O-CD2 3.17Å; E359-H363 PolarHBondContact O-N 2.85Å
360	M	77.8	Confident	79.6	Confident	2 Å²	2	56.1 Å²	56.1	1%	0.01	33%	0.325	C	S	.	.	H	α-helix	trans	-64.4	-29.9	178.4	-70.1	-69.3	170.8	0	0	113.1	L314 L318 F329 L356 E358 H363 I368 L369 V372	L314-M360 HydrophobicContact CD1-CE 4Å; L318-M360 HydrophobicContact CD1-CE 4.21Å; L318-M360 HydrophobicContact CD2-CE 3.75Å; L318-M360 HydrophobicContact CD2-SD 4.33Å; L318-M360 HydrophobicContact CG-CE 4.37Å; F329-M360 HydrophobicContact CD1-CE 4.06Å; F329-M360 HydrophobicContact CE1-CE 3.29Å; F329-M360 HydrophobicContact CE1-SD 4.38Å; F329-M360 HydrophobicContact CZ-CE 3.81Å; L356-M360 HydrophobicContact CD1-CE 3.69Å; L356-M360 HydrophobicContact CD1-CG 4.14Å; L356-M360 HydrophobicContact CG-CE 4.37Å; L356-M360 HydrophobicContact CG-CG 4.2Å; L356-M360 VanDerWaalsContact O-CB 3.3Å; L356-M360 WeakPolarHBondContact O-CB 3.47Å; L356-M360 WeakPolarHBondContact O-CG 3.42Å; L356-M360 PolarHBondContact O-N 3.49Å; E358-M360 PolarHBondContact O-N 3.34Å; M360-H363 PolarHBondContact O-N 2.75Å; M360-I368 HydrophobicContact CE-CG2 4.41Å; M360-I368 HydrophobicContact SD-CG2 3.56Å; M360-I368 VanDerWaalsContact SD-CG2 3.56Å; M360-L369 HydrophobicContact CB-CB 4.47Å; M360-L369 HydrophobicContact CB-CD1 3.92Å; M360-V372 HydrophobicContact CG-CG2 4.42Å
361	S	74.9	Confident	79.6	Confident	55 Å²	55	51.7 Å²	51.7	39%	0.385	29%	0.293	S	S	.	.	H	α-helix	trans	-67.8	-36.7	172.1	-61.5	0	0	0	0	111.5	E357 E358 E359 H363 G364 L369	E357-S361 WeakPolarHBondContact O-CB 3.13Å; E357-S361 PolarHBondContact O-N 3.23Å; E357-S361 PolarHBondContact O-OG 2.95Å; E358-S361 WeakPolarHBondContact O-CB 3.2Å; E358-S361 PolarHBondContact O-N 3.17Å; E359-S361 VanDerWaalsContact C-N 3.27Å; E359-S361 PolarHBondContact O-N 3.25Å; S361-H363 VanDerWaalsContact C-N 3.28Å; S361-H363 PolarHBondContact O-N 2.7Å; S361-G364 PolarHBondContact O-N 2.98Å; S361-L369 WeakPolarHBondContact OG-CD1 3.24Å; S361-L369 WeakPolarHBondContact OG-CD2 3.45Å
362	G	62.7	Low	79.6	Confident	71 Å²	71	46.7 Å²	46.7	73%	0.732	27%	0.267	S	S	*	.	H	α-helix	trans	-62.9	-29.3	174.5	0	0	0	0	0	114.3	E358 E359 G364	E358-G362 PolarHBondContact O-N 2.83Å; E358-G362 VanDerWaalsContact O-N 3.09Å; E359-G362 WeakPolarHBondContact O-CA 3.29Å; E359-G362 PolarHBondContact O-N 3.35Å; G362-G364 VanDerWaalsContact C-N 3.35Å
363	H	64.8	Low	80	Confident	77 Å²	77	47.1 Å²	47.1	36%	0.356	27%	0.266	S	S	.	.	T	Hydrogen-bonded Turn	trans	-80.7	-7.8	176.8	-66.2	-67.8	0	0	0	114.6	L318 I324 E359 M360 S361 L365	L318-H363 WeakPolarHBondContact CD2-NE2 3.43Å; I324-H363 HydrophobicContact CD1-CB 3.95Å; E359-H363 PolarHBondContact O-CD2 3.17Å; E359-H363 PolarHBondContact O-N 2.85Å; M360-H363 PolarHBondContact O-N 2.75Å; S361-H363 VanDerWaalsContact C-N 3.28Å; S361-H363 PolarHBondContact O-N 2.7Å; H363-L365 HydrophobicContact CB-CG 4.46Å; H363-L365 PolarHBondContact O-N 2.92Å; H363-L365 VanDerWaalsContact O-N 3.15Å
364	G	60.7	Low	80.5	Confident	51 Å²	51	37.8 Å²	37.8	53%	0.526	23%	0.226	S	C	.	.	T	Hydrogen-bonded Turn	trans	70.5	2.1	177.6	0	0	0	0	0	116.2	S361 G362 N366	S361-G364 PolarHBondContact O-N 2.98Å; G362-G364 VanDerWaalsContact C-N 3.35Å; G364-N366 PolarHBondContact O-N 2.99Å
365	L	75	Confident	81.1	Confident	47 Å²	47	36.4 Å²	36.4	25%	0.246	22%	0.216	C	C	.	.			trans	-83.6	74.6	-174.6	-60.4	-179.1	0	0	0	111.8	L283 I324 H363 T367 I368 L369	L283-L365 HydrophobicContact CD2-CD1 4.45Å; L283-L365 HydrophobicContact CD2-CD2 3.94Å; I324-L365 HydrophobicContact CB-CD1 3.99Å; I324-L365 HydrophobicContact CD1-CD1 3.91Å; I324-L365 HydrophobicContact CG1-CD1 4.47Å; I324-L365 HydrophobicContact CG2-CD1 4.37Å; H363-L365 HydrophobicContact CB-CG 4.46Å; H363-L365 PolarHBondContact O-N 2.92Å; H363-L365 VanDerWaalsContact O-N 3.15Å; L365-T367 PolarHBondContact O-N 3.22Å; L365-I368 HydrophobicContact CB-CB 4.14Å; L365-I368 HydrophobicContact CB-CD1 4.2Å; L365-I368 HydrophobicContact CB-CG1 4.43Å; L365-I368 HydrophobicContact CD1-CD1 3.75Å; L365-I368 PolarHBondContact O-N 3.17Å; L365-L369 PolarHBondContact O-N 3.4Å
366	N	80	Confident	81.6	Confident	110 Å²	110	36.8 Å²	36.8	59%	0.588	22%	0.217	S	C	*	.	H	α-helix	trans	-47.5	-36.5	-176.5	-77.2	-34.3	0	0	0	115.1	G364 S370	G364-N366 PolarHBondContact O-N 2.99Å; N366-S370 WeakPolarHBondContact O-CB 3.42Å; N366-S370 PolarHBondContact O-N 3.35Å; N366-S370 PolarHBondContact O-OG 3.08Å
367	T	83	Confident	81.9	Confident	15 Å²	15	39.1 Å²	39.1	9%	0.092	23%	0.229	C	C	.	.	H	α-helix	trans	-62.6	-52.4	174.4	-49.8	0	0	0	0	111.4	I245 I287 L365 S370 I371	I245-T367 WeakPolarHBondContact CD1-OG1 3.36Å; I245-T367 HydrophobicContact CG1-CG2 4.19Å; I287-T367 HydrophobicContact CB-CG2 4.38Å; I287-T367 HydrophobicContact CD1-CG2 4.34Å; I287-T367 HydrophobicContact CG2-CG2 3.66Å; L365-T367 PolarHBondContact O-N 3.22Å; T367-S370 PolarHBondContact O-N 3.12Å; T367-I371 HydrophobicContact CG2-CD1 4.13Å; T367-I371 WeakPolarHBondContact O-CG1 3.27Å; T367-I371 PolarHBondContact O-N 3.33Å
368	I	86.3	Confident	82.5	Confident	1 Å²	1	38.2 Å²	38.2	1%	0.005	22%	0.224	C	C	.	.	H	α-helix	trans	-65.2	-43	-178.3	-69.3	175.3	0	0	0	110.4	I287 I324 F329 I330 L333 M360 L365 S370 I371 V372	I287-I368 HydrophobicContact CD1-CD1 4.15Å; I287-I368 HydrophobicContact CD1-CG1 3.91Å; I324-I368 HydrophobicContact CG2-CD1 3.76Å; F329-I368 HydrophobicContact CE1-CG2 4.24Å; I330-I368 HydrophobicContact CD1-CD1 3.91Å; I330-I368 HydrophobicContact CG1-CD1 3.87Å; L333-I368 HydrophobicContact CD2-CB 4.48Å; L333-I368 HydrophobicContact CD2-CG1 4.47Å; L333-I368 HydrophobicContact CD2-CG2 3.82Å; M360-I368 HydrophobicContact CE-CG2 4.41Å; M360-I368 HydrophobicContact SD-CG2 3.56Å; M360-I368 VanDerWaalsContact SD-CG2 3.56Å; L365-I368 HydrophobicContact CB-CB 4.14Å; L365-I368 HydrophobicContact CB-CD1 4.2Å; L365-I368 HydrophobicContact CB-CG1 4.43Å; L365-I368 HydrophobicContact CD1-CD1 3.75Å; L365-I368 PolarHBondContact O-N 3.17Å; I368-S370 VanDerWaalsContact C-N 3.28Å; I368-S370 PolarHBondContact O-N 3.46Å; I368-I371 PolarHBondContact O-N 3.03Å; I368-V372 HydrophobicContact CG2-CG2 4.48Å; I368-V372 WeakPolarHBondContact O-CG2 3.35Å; I368-V372 PolarHBondContact O-N 3.18Å
369	L	88.8	Confident	83.2	Confident	9 Å²	9	32.8 Å²	32.8	5%	0.047	20%	0.2	C	C	.	.	H	α-helix	trans	-58.7	-39.1	174.4	179.5	61.8	0	0	0	112.3	E357 M360 S361 L365 R373	E357-L369 HydrophobicContact CG-CD1 3.76Å; E357-L369 WeakPolarHBondContact O-CD1 3.37Å; M360-L369 HydrophobicContact CB-CB 4.47Å; M360-L369 HydrophobicContact CB-CD1 3.92Å; S361-L369 WeakPolarHBondContact OG-CD1 3.24Å; S361-L369 WeakPolarHBondContact OG-CD2 3.45Å; L365-L369 PolarHBondContact O-N 3.4Å; L369-R373 VanDerWaalsContact CD2-NH1 3.26Å; L369-R373 WeakPolarHBondContact O-CB 3.47Å; L369-R373 WeakPolarHBondContact O-CG 3.36Å; L369-R373 PolarHBondContact O-N 3.44Å
370	S	89.7	Confident	84.1	Confident	12 Å²	12	34 Å²	34	8%	0.084	20%	0.202	C	C	.	.	H	α-helix	trans	-71	-37.9	176.1	-62.4	0	0	0	0	112.8	I245 N366 T367 I368 C374	I245-S370 WeakPolarHBondContact CG2-OG 3.31Å; N366-S370 WeakPolarHBondContact O-CB 3.42Å; N366-S370 PolarHBondContact O-N 3.35Å; N366-S370 PolarHBondContact O-OG 3.08Å; T367-S370 PolarHBondContact O-N 3.12Å; I368-S370 VanDerWaalsContact C-N 3.28Å; I368-S370 PolarHBondContact O-N 3.46Å; S370-C374 VanDerWaalsContact O-CB 3.23Å; S370-C374 WeakPolarHBondContact O-CB 3.09Å; S370-C374 PolarHBondContact O-N 3.47Å
371	I	90	Very high	84.9	Confident	2 Å²	2	34.3 Å²	34.3	1%	0.01	20%	0.203	C	C	.	.	H	α-helix	trans	-62.4	-47.6	172.8	-63.7	163.5	0	0	0	110	C249 I287 L291 L333 T367 I368 C374 I375	C249-I371 HydrophobicContact CB-CG1 3.75Å; C249-I371 WeakPolarHBondContact SG-CG1 3.49Å; I287-I371 HydrophobicContact CG2-CD1 3.74Å; L291-I371 HydrophobicContact CD1-CD1 4.26Å; L333-I371 HydrophobicContact CD1-CG2 3.91Å; L333-I371 HydrophobicContact CD2-CB 4.22Å; L333-I371 HydrophobicContact CD2-CG2 3.95Å; L333-I371 HydrophobicContact CG-CB 4.47Å; L333-I371 HydrophobicContact CG-CG2 3.66Å; T367-I371 HydrophobicContact CG2-CD1 4.13Å; T367-I371 WeakPolarHBondContact O-CG1 3.27Å; T367-I371 PolarHBondContact O-N 3.33Å; I368-I371 PolarHBondContact O-N 3.03Å; I371-C374 PolarHBondContact O-N 2.82Å; I371-I375 HydrophobicContact CG2-CD1 3.55Å; I371-I375 HydrophobicContact CG2-CG1 4.32Å; I371-I375 WeakPolarHBondContact O-CD1 3.38Å; I371-I375 VanDerWaalsContact O-CG1 3.24Å; I371-I375 WeakPolarHBondContact O-CG1 3.38Å; I371-I375 PolarHBondContact O-N 3.49Å
372	V	91.6	Very high	85.9	Confident	0 Å²	0	31.7 Å²	31.7	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-58.8	-52.7	177.9	169.5	0	0	0	0	111.2	L333 F345 L356 M360 I368 C374 I375 Q376	L333-V372 HydrophobicContact CD1-CG2 3.99Å; L333-V372 HydrophobicContact CD2-CG2 4.42Å; F345-V372 HydrophobicContact CD2-CG1 4.47Å; F345-V372 HydrophobicContact CE2-CB 4.43Å; F345-V372 HydrophobicContact CE2-CG1 4.05Å; F345-V372 HydrophobicContact CE2-CG2 4.4Å; F345-V372 HydrophobicContact CZ-CG1 4.42Å; F345-V372 HydrophobicContact CZ-CG2 4.04Å; L356-V372 HydrophobicContact CD2-CG1 3.98Å; L356-V372 HydrophobicContact CD2-CG2 4.4Å; L356-V372 HydrophobicContact CG-CG1 4.16Å; M360-V372 HydrophobicContact CG-CG2 4.42Å; I368-V372 HydrophobicContact CG2-CG2 4.48Å; I368-V372 WeakPolarHBondContact O-CG2 3.35Å; I368-V372 PolarHBondContact O-N 3.18Å; V372-C374 VanDerWaalsContact C-N 3.32Å; V372-C374 PolarHBondContact O-N 3.49Å; V372-I375 PolarHBondContact O-N 3.04Å; V372-Q376 HydrophobicContact CG1-CG 4.44Å; V372-Q376 WeakPolarHBondContact O-CG 3.38Å; V372-Q376 PolarHBondContact O-N 2.94Å
373	R	92.2	Very high	87.5	Confident	42 Å²	42	28.3 Å²	28.3	16%	0.158	15%	0.15	C	C	.	.	H	α-helix	trans	-55.2	-45.5	175.8	-77.8	-176.8	174.4	120.8	5.7	112.3	E357 L369 I375 Q376 N377 Y381 E384	E357-R373 HydrophobicContact CG-CG 4.06Å; E357-R373 IonicContact OE1-CZ 3.84Å; E357-R373 IonicContact OE1-NE 3.74Å; E357-R373 PolarHBondContact OE1-NE 3.45Å; E357-R373 IonicContact OE1-NH2 3.34Å; E357-R373 PolarHBondContact OE1-NH2 2.92Å; L369-R373 VanDerWaalsContact CD2-NH1 3.26Å; L369-R373 WeakPolarHBondContact O-CB 3.47Å; L369-R373 WeakPolarHBondContact O-CG 3.36Å; L369-R373 PolarHBondContact O-N 3.44Å; R373-I375 PolarHBondContact O-N 3.41Å; R373-Q376 PolarHBondContact O-N 3.46Å; R373-N377 CarbonylContact O-C 3.6Å; R373-N377 PolarHBondContact O-N 3.03Å; R373-Y381 HydrophobicContact CB-CD2 3.85Å; R373-E384 WeakPolarHBondContact CD-OE2 3.49Å; R373-E384 IonicContact CZ-OE2 3.79Å; R373-E384 IonicContact NE-OE2 2.73Å; R373-E384 PolarHBondContact NE-OE2 3.19Å; R373-E384 VanDerWaalsContact NE-OE2 3.16Å
374	C	91.6	Very high	89	Confident	1 Å²	1	25.9 Å²	25.9	1%	0.007	14%	0.138	C	C	.	.	H	α-helix	trans	-69.4	-30.6	-178.5	-170.6	0	0	0	0	113.4	S250 S370 I371 V372 R378 Y381	S250-C374 VanDerWaalsContact CA-SG 3.52Å; S370-C374 VanDerWaalsContact O-CB 3.23Å; S370-C374 WeakPolarHBondContact O-CB 3.09Å; S370-C374 PolarHBondContact O-N 3.47Å; I371-C374 PolarHBondContact O-N 2.82Å; V372-C374 VanDerWaalsContact C-N 3.32Å; V372-C374 PolarHBondContact O-N 3.49Å; C374-R378 PolarHBondContact O-N 3.1Å; C374-Y381 HydrophobicContact CB-CD1 4.35Å; C374-Y381 HydrophobicContact CB-CG 4.25Å
375	I	91.5	Very high	90.6	Very high	3 Å²	3	23.9 Å²	23.9	2%	0.015	12%	0.115	C	C	.	.	H	α-helix	trans	-70.6	-44.5	172	-69.7	157.8	0	0	0	110.7	L333 Y338 L341 R342 F345 I371 V372 R373	L333-I375 HydrophobicContact CD1-CD1 3.48Å; L333-I375 VanDerWaalsContact CD1-CD1 3.48Å; L333-I375 HydrophobicContact CG-CD1 4.38Å; Y338-I375 HydrophobicContact CD1-CB 4.25Å; Y338-I375 HydrophobicContact CD1-CG1 3.73Å; Y338-I375 HydrophobicContact CD1-CG2 4.39Å; Y338-I375 HydrophobicContact CE1-CG1 3.86Å; L341-I375 HydrophobicContact CB-CD1 4.42Å; L341-I375 HydrophobicContact CB-CG2 3.67Å; L341-I375 HydrophobicContact CD1-CD1 3.75Å; L341-I375 HydrophobicContact CD1-CG1 4.48Å; R342-I375 VanDerWaalsContact CD-O 3.29Å; R342-I375 WeakPolarHBondContact CD-O 3.44Å; R342-I375 HydrophobicContact CG-CG2 3.98Å; R342-I375 VanDerWaalsContact CG-O 3.27Å; R342-I375 WeakPolarHBondContact CG-O 3.46Å; F345-I375 HydrophobicContact CD2-CG2 4.16Å; F345-I375 HydrophobicContact CE2-CB 3.88Å; F345-I375 HydrophobicContact CE2-CD1 4.17Å; F345-I375 HydrophobicContact CE2-CG2 3.54Å; F345-I375 HydrophobicContact CZ-CD1 4.07Å; F345-I375 HydrophobicContact CZ-CG2 4.28Å; I371-I375 HydrophobicContact CG2-CD1 3.55Å; I371-I375 HydrophobicContact CG2-CG1 4.32Å; I371-I375 WeakPolarHBondContact O-CD1 3.38Å; I371-I375 VanDerWaalsContact O-CG1 3.24Å; I371-I375 WeakPolarHBondContact O-CG1 3.38Å; I371-I375 PolarHBondContact O-N 3.49Å; V372-I375 PolarHBondContact O-N 3.04Å; R373-I375 PolarHBondContact O-N 3.41Å
376	Q	90.6	Very high	91.7	Very high	59 Å²	59	21.6 Å²	21.6	28%	0.276	10%	0.104	S	C	.	.	H	α-helix	trans	-62.1	-55.1	-179.7	-73.7	172.8	-53.4	0	0	111.2	F345 V372 R373	F345-Q376 HydrophobicContact CD2-CG 3.67Å; F345-Q376 HydrophobicContact CE2-CG 4.22Å; V372-Q376 HydrophobicContact CG1-CG 4.44Å; V372-Q376 WeakPolarHBondContact O-CG 3.38Å; V372-Q376 PolarHBondContact O-N 2.94Å; R373-Q376 PolarHBondContact O-N 3.46Å
377	N	91.3	Very high	92.4	Very high	49 Å²	49	17.1 Å²	17.1	26%	0.262	8%	0.079	S	C	.	.			trans	-156.8	97.6	-179	-175.1	-26.7	0	0	0	110.5	R373 P379 R380 Y381 E418	R373-N377 CarbonylContact O-C 3.6Å; R373-N377 PolarHBondContact O-N 3.03Å; N377-P379 VanDerWaalsContact OD1-CD 3.3Å; N377-P379 WeakPolarHBondContact OD1-CD 3.37Å; N377-R380 HydrophobicContact CB-CB 3.77Å; N377-R380 WeakPolarHBondContact O-CB 3.47Å; N377-R380 PolarHBondContact O-N 3.22Å; N377-R380 VanDerWaalsContact OD1-CB 3.29Å; N377-R380 WeakPolarHBondContact OD1-CB 3.22Å; N377-R380 PolarHBondContact OD1-N 2.79Å; N377-Y381 PolarHBondContact O-N 2.76Å; N377-E418 PolarHBondContact ND2-OE1 3.44Å
378	R	92.9	Very high	92.9	Very high	11 Å²	11	22.3 Å²	22.3	4%	0.042	10%	0.101	C	C	.	.	H	α-helix	trans	-63.5	-44.2	-178.9	-176.9	-177.6	-48.8	91.7	-3.9	113.6	D137 C374 R380 Y381 F382	D137-R378 IonicContact OD1-CZ 2.75Å; D137-R378 IonicContact OD1-NH1 2.6Å; D137-R378 PolarHBondContact OD1-NH1 3.2Å; D137-R378 IonicContact OD1-NH2 3.68Å; D137-R378 IonicContact OD2-CZ 3.2Å; D137-R378 IonicContact OD2-NH1 2.8Å; D137-R378 PolarHBondContact OD2-NH1 3.32Å; C374-R378 PolarHBondContact O-N 3.1Å; R378-R380 VanDerWaalsContact C-N 3.31Å; R378-R380 PolarHBondContact O-N 3.12Å; R378-Y381 PolarHBondContact O-N 2.92Å; R378-F382 HydrophobicContact CG-CD2 4.15Å; R378-F382 HydrophobicContact CG-CE2 3.71Å; R378-F382 VanDerWaalsContact O-CD2 3.28Å; R378-F382 WeakPolarHBondContact O-CD2 3.49Å; R378-F382 PolarHBondContact O-N 3.13Å
379	P	94.7	Very high	93.2	Very high	11 Å²	11	22.4 Å²	22.4	7%	0.071	10%	0.101	C	C	.	.	H	α-helix	trans	-56	-43.3	171.8	-28.9	35.7	0	0	0	113.5	N377 F382 A383 Q414 I415 E418	N377-P379 VanDerWaalsContact OD1-CD 3.3Å; N377-P379 WeakPolarHBondContact OD1-CD 3.37Å; P379-F382 PolarHBondContact O-N 2.93Å; P379-A383 WeakPolarHBondContact O-CB 3.46Å; P379-A383 PolarHBondContact O-N 2.85Å; P379-Q414 HydrophobicContact CB-CB 3.63Å; P379-Q414 HydrophobicContact CG-CB 3.7Å; P379-Q414 HydrophobicContact CG-CG 4.48Å; P379-I415 HydrophobicContact CB-CG1 4.01Å; P379-E418 HydrophobicContact CB-CG 4.29Å
380	R	95.2	Very high	93.3	Very high	87 Å²	87	22.7 Å²	22.7	33%	0.328	10%	0.103	S	C	.	.	H	α-helix	trans	-63.6	-42.5	176.5	-173.1	-166.8	176.2	99.2	-14	112.7	N377 R378 F382 A383 E384 E418 L422	N377-R380 HydrophobicContact CB-CB 3.77Å; N377-R380 WeakPolarHBondContact O-CB 3.47Å; N377-R380 PolarHBondContact O-N 3.22Å; N377-R380 VanDerWaalsContact OD1-CB 3.29Å; N377-R380 WeakPolarHBondContact OD1-CB 3.22Å; N377-R380 PolarHBondContact OD1-N 2.79Å; R378-R380 VanDerWaalsContact C-N 3.31Å; R378-R380 PolarHBondContact O-N 3.12Å; R380-F382 VanDerWaalsContact C-N 3.3Å; R380-F382 PolarHBondContact O-N 3.12Å; R380-A383 CarbonylContact O-C 3.12Å; R380-A383 WeakPolarHBondContact O-CA 3.25Å; R380-A383 WeakPolarHBondContact O-CB 3.26Å; R380-A383 PolarHBondContact O-N 3.43Å; R380-A383 VanDerWaalsContact O-N 3.08Å; R380-E384 HydrophobicContact CG-CG 4.44Å; R380-E384 IonicContact CZ-OE1 3.42Å; R380-E384 IonicContact NE-OE1 2.66Å; R380-E384 PolarHBondContact NE-OE1 3.1Å; R380-E384 WeakPolarHBondContact O-CG 3.24Å; R380-E384 PolarHBondContact O-N 2.91Å; R380-E418 HydrophobicContact CB-CB 4.27Å; R380-E418 HydrophobicContact CB-CG 3.94Å; R380-E418 WeakPolarHBondContact CG-OE2 3.46Å; R380-E418 IonicContact NH1-OE2 2.77Å; R380-L422 HydrophobicContact CG-CD1 3.88Å
381	Y	95	Very high	93.2	Very high	8 Å²	8	28.2 Å²	28.2	3%	0.031	13%	0.126	C	C	.	.	H	α-helix	trans	-55.9	-44	175.3	171.7	-101.1	0	0	0	112.1	E246 R373 C374 N377 R378 K385	E246-Y381 WeakPolarHBondContact CA-OH 3.47Å; E246-Y381 HydrophobicContact CG-CE1 4.4Å; R373-Y381 HydrophobicContact CB-CD2 3.85Å; C374-Y381 HydrophobicContact CB-CD1 4.35Å; C374-Y381 HydrophobicContact CB-CG 4.25Å; N377-Y381 PolarHBondContact O-N 2.76Å; R378-Y381 PolarHBondContact O-N 2.92Å; Y381-K385 PolarHBondContact O-N 2.99Å; Y381-K385 WeakPolarHBondContact OH-CE 3.47Å
382	F	96.6	Very high	92.8	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-69.1	-37.1	173.9	-70.8	-59.6	0	0	0	112.8	E246 S250 R378 P379 R380 K385 L386 I403 R407 I415	E246-F382 HydrophobicContact CG-CE1 4.19Å; S250-F382 WeakPolarHBondContact OG-CZ 3.17Å; R378-F382 HydrophobicContact CG-CD2 4.15Å; R378-F382 HydrophobicContact CG-CE2 3.71Å; R378-F382 VanDerWaalsContact O-CD2 3.28Å; R378-F382 WeakPolarHBondContact O-CD2 3.49Å; R378-F382 PolarHBondContact O-N 3.13Å; P379-F382 PolarHBondContact O-N 2.93Å; R380-F382 VanDerWaalsContact C-N 3.3Å; R380-F382 PolarHBondContact O-N 3.12Å; F382-K385 PolarHBondContact O-N 2.98Å; F382-L386 WeakPolarHBondContact O-CB 3.25Å; F382-L386 WeakPolarHBondContact O-CG 3.28Å; F382-L386 PolarHBondContact O-N 3.47Å; F382-I403 HydrophobicContact CB-CG2 4.05Å; F382-I403 HydrophobicContact CD1-CD1 4.16Å; F382-I403 HydrophobicContact CD1-CG1 4.04Å; F382-I403 HydrophobicContact CD1-CG2 3.94Å; F382-I403 HydrophobicContact CG-CG2 4.21Å; F382-R407 HydrophobicContact CD2-CG 4.25Å; F382-R407 HydrophobicContact CE2-CG 4.17Å; F382-R407 HydrophobicContact CG-CG 4.46Å; F382-R407 HydrophobicContact CZ-CG 4.3Å; F382-I415 HydrophobicContact CB-CD1 3.78Å; F382-I415 HydrophobicContact CB-CG1 4.01Å; F382-I415 HydrophobicContact CB-CG2 4.21Å; F382-I415 HydrophobicContact CD2-CD1 3.9Å; F382-I415 HydrophobicContact CG-CD1 4.11Å
383	A	97.1	Very high	92	Very high	0 Å²	0	33.9 Å²	33.9	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-60.8	-45.8	174.4	0	0	0	0	0	111.9	P379 R380 K385 L386 I387 I415 E418 F419 L422	P379-A383 WeakPolarHBondContact O-CB 3.46Å; P379-A383 PolarHBondContact O-N 2.85Å; R380-A383 CarbonylContact O-C 3.12Å; R380-A383 WeakPolarHBondContact O-CA 3.25Å; R380-A383 WeakPolarHBondContact O-CB 3.26Å; R380-A383 PolarHBondContact O-N 3.43Å; R380-A383 VanDerWaalsContact O-N 3.08Å; A383-K385 VanDerWaalsContact C-N 3.35Å; A383-K385 PolarHBondContact O-N 2.93Å; A383-L386 PolarHBondContact O-N 3.41Å; A383-I387 VanDerWaalsContact O-CG1 3.24Å; A383-I387 WeakPolarHBondContact O-CG1 3.39Å; A383-I387 PolarHBondContact O-N 2.95Å; A383-I415 HydrophobicContact CB-CG2 4.49Å; A383-E418 HydrophobicContact CB-CB 3.77Å; A383-F419 HydrophobicContact CB-CB 3.99Å; A383-L422 HydrophobicContact CB-CD1 4.1Å
384	E	95.3	Very high	91.2	Very high	25 Å²	25	37.5 Å²	37.5	12%	0.117	18%	0.175	C	C	.	.	H	α-helix	trans	-61.3	-39.7	176.2	-72.1	176.9	-163.1	0	0	112.5	R373 R380 I387 K388 L422	R373-E384 WeakPolarHBondContact CD-OE2 3.49Å; R373-E384 IonicContact CZ-OE2 3.79Å; R373-E384 IonicContact NE-OE2 2.73Å; R373-E384 PolarHBondContact NE-OE2 3.19Å; R373-E384 VanDerWaalsContact NE-OE2 3.16Å; R380-E384 HydrophobicContact CG-CG 4.44Å; R380-E384 IonicContact CZ-OE1 3.42Å; R380-E384 IonicContact NE-OE1 2.66Å; R380-E384 PolarHBondContact NE-OE1 3.1Å; R380-E384 WeakPolarHBondContact O-CG 3.24Å; R380-E384 PolarHBondContact O-N 2.91Å; E384-I387 PolarHBondContact O-N 3.1Å; E384-K388 WeakPolarHBondContact O-CG 3.34Å; E384-K388 PolarHBondContact O-N 3.32Å; E384-K388 VanDerWaalsContact O-N 3.07Å; E384-L422 HydrophobicContact CG-CD1 3.57Å
385	K	95.2	Very high	90.5	Very high	9 Å²	9	44.2 Å²	44.2	4%	0.039	20%	0.204	C	C	.	.	H	α-helix	trans	-65.5	-45.2	172.1	-87.6	-160.9	167.1	-132.1	0	112.4	D242 E246 Y381 F382 A383 I387 K388 A389 I403	D242-K385 PolarHBondContact O-NZ 3.13Å; D242-K385 WeakPolarHBondContact OD1-CE 3.34Å; D242-K385 IonicContact OD1-NZ 3.62Å; D242-K385 PolarHBondContact OD1-NZ 3.49Å; D242-K385 IonicContact OD2-NZ 3.75Å; D242-K385 PolarHBondContact OD2-NZ 2.96Å; E246-K385 HydrophobicContact CB-CD 4.42Å; E246-K385 HydrophobicContact CG-CD 3.94Å; E246-K385 WeakPolarHBondContact OE2-CD 3.38Å; E246-K385 WeakPolarHBondContact OE2-CE 3.35Å; E246-K385 IonicContact OE2-NZ 3.47Å; E246-K385 PolarHBondContact OE2-NZ 2.77Å; Y381-K385 PolarHBondContact O-N 2.99Å; Y381-K385 WeakPolarHBondContact OH-CE 3.47Å; F382-K385 PolarHBondContact O-N 2.98Å; A383-K385 VanDerWaalsContact C-N 3.35Å; A383-K385 PolarHBondContact O-N 2.93Å; K385-I387 VanDerWaalsContact C-N 3.3Å; K385-I387 PolarHBondContact O-N 3.27Å; K385-K388 WeakPolarHBondContact O-CB 3.28Å; K385-K388 PolarHBondContact O-N 3.18Å; K385-A389 PolarHBondContact O-N 3Å; K385-I403 HydrophobicContact CB-CD1 3.66Å; K385-I403 HydrophobicContact CD-CD1 4.29Å
386	L	96.3	Very high	90.3	Very high	0 Å²	0	46.2 Å²	46.2	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-61.1	-37.5	175	-74.6	169.9	0	0	0	111.9	F382 A383 A389 T390 I400 I403 I404 I415 F419 L427	F382-L386 WeakPolarHBondContact O-CB 3.25Å; F382-L386 WeakPolarHBondContact O-CG 3.28Å; F382-L386 PolarHBondContact O-N 3.47Å; A383-L386 PolarHBondContact O-N 3.41Å; L386-A389 PolarHBondContact O-N 3.34Å; L386-T390 VanDerWaalsContact O-CB 3.32Å; L386-T390 WeakPolarHBondContact O-CB 3.36Å; L386-T390 VanDerWaalsContact O-CG2 3.27Å; L386-T390 WeakPolarHBondContact O-CG2 3.35Å; L386-T390 PolarHBondContact O-N 3.38Å; L386-T390 PolarHBondContact O-OG1 3.17Å; L386-I400 HydrophobicContact CD2-CG1 4.32Å; L386-I400 HydrophobicContact CD2-CG2 4.46Å; L386-I403 HydrophobicContact CD1-CG2 3.88Å; L386-I403 HydrophobicContact CD2-CB 4.11Å; L386-I403 HydrophobicContact CD2-CD1 4.23Å; L386-I403 HydrophobicContact CD2-CG2 4.14Å; L386-I403 HydrophobicContact CG-CB 4.38Å; L386-I403 HydrophobicContact CG-CD1 4.06Å; L386-I403 HydrophobicContact CG-CG2 3.96Å; L386-I404 HydrophobicContact CD2-CG1 4.44Å; L386-I415 HydrophobicContact CD1-CG2 3.62Å; L386-F419 HydrophobicContact CB-CD2 3.81Å; L386-F419 HydrophobicContact CB-CE2 3.78Å; L386-L427 HydrophobicContact CB-CD1 4.35Å; L386-L427 HydrophobicContact CD1-CD1 4.25Å; L386-L427 HydrophobicContact CD1-CD2 3.94Å; L386-L427 HydrophobicContact CD2-CD1 4.49Å
387	I	95.2	Very high	90.3	Very high	15 Å²	15	44.2 Å²	44.2	8%	0.077	21%	0.206	C	C	.	.	H	α-helix	trans	-64.6	-40.7	175	-69.6	161.9	0	0	0	111	A383 E384 K385 T390 K391 F419 L422 Y423	A383-I387 VanDerWaalsContact O-CG1 3.24Å; A383-I387 WeakPolarHBondContact O-CG1 3.39Å; A383-I387 PolarHBondContact O-N 2.95Å; E384-I387 PolarHBondContact O-N 3.1Å; K385-I387 VanDerWaalsContact C-N 3.3Å; K385-I387 PolarHBondContact O-N 3.27Å; I387-T390 WeakPolarHBondContact CA-OG1 3.42Å; I387-T390 PolarHBondContact O-OG1 3.41Å; I387-K391 VanDerWaalsContact O-CG 3.28Å; I387-K391 WeakPolarHBondContact O-CG 3.34Å; I387-K391 PolarHBondContact O-N 3.03Å; I387-F419 HydrophobicContact CB-CE2 4.36Å; I387-F419 HydrophobicContact CD1-CD2 4.32Å; I387-F419 HydrophobicContact CG1-CD2 3.6Å; I387-F419 HydrophobicContact CG1-CE1 4.5Å; I387-F419 HydrophobicContact CG1-CE2 3.5Å; I387-F419 HydrophobicContact CG1-CG 4.16Å; I387-F419 HydrophobicContact CG1-CZ 3.98Å; I387-L422 HydrophobicContact CD1-CB 3.45Å; I387-L422 VanDerWaalsContact CD1-CB 3.45Å; I387-L422 HydrophobicContact CD1-CD1 3.89Å; I387-L422 HydrophobicContact CD1-CG 4.34Å; I387-Y423 HydrophobicContact CG1-CG 4.27Å; I387-Y423 HydrophobicContact CG2-CD2 3.97Å; I387-Y423 HydrophobicContact CG2-CE2 4.4Å; I387-Y423 HydrophobicContact CG2-CG 4.32Å
388	K	93.5	Very high	90.3	Very high	125 Å²	125	44.1 Å²	44.1	54%	0.543	20%	0.204	S	C	.	.	H	α-helix	trans	-62.5	-48	174.2	-71	165.4	-175.8	171.1	0	111.3	E384 K385	E384-K388 WeakPolarHBondContact O-CG 3.34Å; E384-K388 PolarHBondContact O-N 3.32Å; E384-K388 VanDerWaalsContact O-N 3.07Å; K385-K388 WeakPolarHBondContact O-CB 3.28Å; K385-K388 PolarHBondContact O-N 3.18Å
389	A	92.9	Very high	90.3	Very high	2 Å²	2	44 Å²	44	2%	0.017	20%	0.204	C	C	.	.	H	α-helix	trans	-65.9	-45.5	-178.9	0	0	0	0	0	112.4	K385 L386 K391 N392 T393 D396 T399 I400	K385-A389 PolarHBondContact O-N 3Å; L386-A389 PolarHBondContact O-N 3.34Å; A389-K391 VanDerWaalsContact C-N 3.29Å; A389-K391 PolarHBondContact O-N 3.09Å; A389-N392 CarbonylContact O-C 3.57Å; A389-N392 PolarHBondContact O-N 3.04Å; A389-N392 VanDerWaalsContact O-N 3.1Å; A389-T393 WeakPolarHBondContact O-CA 3.31Å; A389-T393 PolarHBondContact O-N 3.5Å; A389-T393 VanDerWaalsContact O-N 3.1Å; A389-D396 HydrophobicContact CB-CB 3.98Å; A389-D396 WeakPolarHBondContact CB-OD2 3.42Å; A389-T399 HydrophobicContact CB-CG2 4.49Å; A389-I400 HydrophobicContact CB-CD1 4.03Å; A389-I400 HydrophobicContact CB-CG1 3.6Å
390	T	90.5	Very high	90.3	Very high	15 Å²	15	43.5 Å²	43.5	9%	0.092	20%	0.201	C	C	.	.	H	α-helix	trans	-68.6	-20.9	-177.9	51.2	0	0	0	0	114.3	L386 I387 N392 T393 I400 F419 L427 C430 L431	L386-T390 VanDerWaalsContact O-CB 3.32Å; L386-T390 WeakPolarHBondContact O-CB 3.36Å; L386-T390 VanDerWaalsContact O-CG2 3.27Å; L386-T390 WeakPolarHBondContact O-CG2 3.35Å; L386-T390 PolarHBondContact O-N 3.38Å; L386-T390 PolarHBondContact O-OG1 3.17Å; I387-T390 WeakPolarHBondContact CA-OG1 3.42Å; I387-T390 PolarHBondContact O-OG1 3.41Å; T390-N392 PolarHBondContact O-N 3.3Å; T390-T393 WeakPolarHBondContact CA-OG1 3.33Å; T390-T393 PolarHBondContact O-OG1 3.24Å; T390-I400 HydrophobicContact CG2-CD1 3.96Å; T390-F419 HydrophobicContact CG2-CE2 4.45Å; T390-F419 HydrophobicContact CG2-CZ 4.44Å; T390-L427 HydrophobicContact CG2-CD1 4.26Å; T390-C430 HydrophobicContact CG2-CB 4.09Å; T390-L431 HydrophobicContact CG2-CD2 4.33Å
391	K	87.9	Confident	90.3	Very high	128 Å²	128	39.4 Å²	39.4	56%	0.557	19%	0.185	S	C	*	.	T	Hydrogen-bonded Turn	trans	-61.4	-28.6	170.3	-77.9	168.4	-179	179.7	0	112.9	I387 A389	I387-K391 VanDerWaalsContact O-CG 3.28Å; I387-K391 WeakPolarHBondContact O-CG 3.34Å; I387-K391 PolarHBondContact O-N 3.03Å; A389-K391 VanDerWaalsContact C-N 3.29Å; A389-K391 PolarHBondContact O-N 3.09Å
392	N	82	Confident	90.4	Very high	107 Å²	107	39 Å²	39	57%	0.572	18%	0.184	S	C	*	.	T	Hydrogen-bonded Turn	trans	-134.1	53.6	174.2	-71.2	-60.7	0	0	0	109.6	A389 T390 E394 K395 D396	A389-N392 CarbonylContact O-C 3.57Å; A389-N392 PolarHBondContact O-N 3.04Å; A389-N392 VanDerWaalsContact O-N 3.1Å; T390-N392 PolarHBondContact O-N 3.3Å; N392-E394 PolarHBondContact O-N 2.89Å; N392-K395 HydrophobicContact CB-CB 4.35Å; N392-K395 PolarHBondContact O-N 3.13Å; N392-D396 PolarHBondContact O-N 3.28Å
393	T	75.1	Confident	90.4	Very high	14 Å²	14	39 Å²	39	9%	0.086	18%	0.184	C	C	.	.	T	Hydrogen-bonded Turn	trans	-43.1	-40.4	-172	-63.8	0	0	0	0	113.5	A389 T390 K395 D396 L397 I400	A389-T393 WeakPolarHBondContact O-CA 3.31Å; A389-T393 PolarHBondContact O-N 3.5Å; A389-T393 VanDerWaalsContact O-N 3.1Å; T390-T393 WeakPolarHBondContact CA-OG1 3.33Å; T390-T393 PolarHBondContact O-OG1 3.24Å; T393-K395 VanDerWaalsContact C-N 3.34Å; T393-K395 PolarHBondContact O-N 3.36Å; T393-D396 PolarHBondContact O-N 3.13Å; T393-L397 HydrophobicContact CG2-CD2 3.95Å; T393-L397 WeakPolarHBondContact O-CG 3.47Å; T393-L397 PolarHBondContact O-N 3.26Å; T393-I400 HydrophobicContact CG2-CD1 3.96Å
394	E	74.1	Confident	90.4	Very high	118 Å²	118	39 Å²	39	55%	0.551	18%	0.184	S	C	*	.	T	Hydrogen-bonded Turn	trans	-70.7	-24.3	-176.3	-65.8	174.9	-175.1	0	0	114.3	N392 R463	N392-E394 PolarHBondContact O-N 2.89Å; E394-R463 IonicContact OE1-NH2 3.31Å; E394-R463 PolarHBondContact OE1-NH2 2.93Å
395	K	78.2	Confident	90.3	Very high	142 Å²	142	38.2 Å²	38.2	62%	0.617	18%	0.181	S	C	*	.	T	Hydrogen-bonded Turn	trans	-82.4	-36.8	171.8	-70.9	-160.6	172.1	-155.9	0	112.8	E100 N392 T393	E100-K395 IonicContact OE1-NZ 2.78Å; E100-K395 PolarHBondContact OE1-NZ 3.09Å; E100-K395 WeakPolarHBondContact OE2-CE 3.38Å; E100-K395 IonicContact OE2-NZ 3.61Å; E100-K395 PolarHBondContact OE2-NZ 3.29Å; N392-K395 HydrophobicContact CB-CB 4.35Å; N392-K395 PolarHBondContact O-N 3.13Å; T393-K395 VanDerWaalsContact C-N 3.34Å; T393-K395 PolarHBondContact O-N 3.36Å
396	D	86.6	Confident	90.3	Very high	45 Å²	45	37.9 Å²	37.9	24%	0.241	18%	0.179	C	C	.	.			trans	-120.2	41	-168.8	-164.5	14.8	0	0	0	114.1	A389 N392 T393 K398 T399 I400	A389-D396 HydrophobicContact CB-CB 3.98Å; A389-D396 WeakPolarHBondContact CB-OD2 3.42Å; N392-D396 PolarHBondContact O-N 3.28Å; T393-D396 PolarHBondContact O-N 3.13Å; D396-K398 PolarHBondContact O-N 3.47Å; D396-T399 VanDerWaalsContact CG-CB 3.49Å; D396-T399 PolarHBondContact O-N 2.66Å; D396-T399 WeakPolarHBondContact OD1-CB 3.41Å; D396-T399 PolarHBondContact OD1-N 3.41Å; D396-T399 PolarHBondContact OD1-OG1 3Å; D396-T399 VanDerWaalsContact OD2-CB 3.31Å; D396-T399 WeakPolarHBondContact OD2-CB 3.49Å; D396-T399 PolarHBondContact OD2-OG1 3.42Å; D396-I400 WeakPolarHBondContact O-CG1 3.41Å; D396-I400 PolarHBondContact O-N 2.98Å
397	L	89.8	Confident	90.2	Very high	17 Å²	17	38 Å²	38	9%	0.089	18%	0.18	C	C	.	.	H	α-helix	trans	-60	-26.2	166.7	-79.6	172.2	0	0	0	111.9	C210 T393 I400 I401 L466	C210-L397 HydrophobicContact CB-CB 4.33Å; C210-L397 HydrophobicContact CB-CD1 3.59Å; C210-L397 VanDerWaalsContact SG-CD1 3.57Å; T393-L397 HydrophobicContact CG2-CD2 3.95Å; T393-L397 WeakPolarHBondContact O-CG 3.47Å; T393-L397 PolarHBondContact O-N 3.26Å; L397-I400 PolarHBondContact O-N 2.89Å; L397-I401 HydrophobicContact CB-CD1 4.33Å; L397-I401 WeakPolarHBondContact O-CB 3.49Å; L397-I401 WeakPolarHBondContact O-CD1 3.45Å; L397-I401 WeakPolarHBondContact O-CG1 3.42Å; L397-I401 PolarHBondContact O-N 3.18Å; L397-L466 HydrophobicContact CD2-CD1 4.36Å
398	K	91.4	Very high	90.1	Very high	48 Å²	48	37.2 Å²	37.2	21%	0.209	18%	0.176	C	C	.	.	H	α-helix	trans	-56.5	-55.8	176.6	-177.1	-170	170.9	-171.5	0	111.1	M105 E229 D240 D396 I400 I401 R402	M105-K398 HydrophobicContact SD-CB 4.5Å; M105-K398 HydrophobicContact SD-CG 4.31Å; E229-K398 WeakPolarHBondContact OE2-CE 3.2Å; E229-K398 IonicContact OE2-NZ 2.87Å; D240-K398 IonicContact OD2-NZ 3.23Å; D240-K398 PolarHBondContact OD2-NZ 3.38Å; D396-K398 PolarHBondContact O-N 3.47Å; K398-I400 PolarHBondContact O-N 3.31Å; K398-I401 PolarHBondContact O-N 3.42Å; K398-R402 WeakPolarHBondContact O-CB 3.29Å; K398-R402 PolarHBondContact O-N 2.91Å
399	T	93.9	Very high	90	Very high	8 Å²	8	33.2 Å²	33.2	5%	0.049	16%	0.159	C	C	.	.	H	α-helix	trans	-66.7	-38	-179.2	-58.2	0	0	0	0	111.6	A389 D396 R402 I403	A389-T399 HydrophobicContact CB-CG2 4.49Å; D396-T399 VanDerWaalsContact CG-CB 3.49Å; D396-T399 PolarHBondContact O-N 2.66Å; D396-T399 WeakPolarHBondContact OD1-CB 3.41Å; D396-T399 PolarHBondContact OD1-N 3.41Å; D396-T399 PolarHBondContact OD1-OG1 3Å; D396-T399 VanDerWaalsContact OD2-CB 3.31Å; D396-T399 WeakPolarHBondContact OD2-CB 3.49Å; D396-T399 PolarHBondContact OD2-OG1 3.42Å; T399-R402 PolarHBondContact O-N 2.69Å; T399-R402 PolarHBondContact OG1-NH2 2.81Å; T399-R402 VanDerWaalsContact OG1-NH2 3.11Å; T399-I403 HydrophobicContact CG2-CD1 3.64Å; T399-I403 HydrophobicContact CG2-CG1 4.24Å; T399-I403 WeakPolarHBondContact O-CB 3.37Å; T399-I403 WeakPolarHBondContact O-CG1 3.48Å; T399-I403 PolarHBondContact O-N 2.81Å
400	I	95.2	Very high	89.9	Confident	0 Å²	0	33.3 Å²	33.3	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-61.7	-46.8	175.9	-63	170.2	0	0	0	111.1	L386 A389 T390 T393 D396 L397 K398 I404 L431 L466	L386-I400 HydrophobicContact CD2-CG1 4.32Å; L386-I400 HydrophobicContact CD2-CG2 4.46Å; A389-I400 HydrophobicContact CB-CD1 4.03Å; A389-I400 HydrophobicContact CB-CG1 3.6Å; T390-I400 HydrophobicContact CG2-CD1 3.96Å; T393-I400 HydrophobicContact CG2-CD1 3.96Å; D396-I400 WeakPolarHBondContact O-CG1 3.41Å; D396-I400 PolarHBondContact O-N 2.98Å; L397-I400 PolarHBondContact O-N 2.89Å; K398-I400 PolarHBondContact O-N 3.31Å; I400-I404 HydrophobicContact CG2-CD1 3.78Å; I400-I404 WeakPolarHBondContact O-CB 3.48Å; I400-I404 WeakPolarHBondContact O-CG1 3.34Å; I400-I404 PolarHBondContact O-N 2.84Å; I400-L431 HydrophobicContact CD1-CD2 4.36Å; I400-L431 HydrophobicContact CG2-CD2 3.79Å; I400-L466 HydrophobicContact CG2-CD1 3.81Å
401	I	95.3	Very high	90	Very high	1 Å²	1	32.9 Å²	32.9	1%	0.005	16%	0.157	C	C	.	.	H	α-helix	trans	-62.7	-47.7	176.3	-67.1	161.6	0	0	0	110.1	M105 C210 C214 A217 L397 K398 I404 V405 L466	M105-I401 HydrophobicContact CE-CB 4.2Å; M105-I401 HydrophobicContact CE-CG2 3.77Å; M105-I401 HydrophobicContact SD-CD1 4.05Å; C210-I401 HydrophobicContact CB-CD1 4.4Å; C214-I401 HydrophobicContact CB-CD1 3.99Å; C214-I401 HydrophobicContact CB-CG1 4.02Å; C214-I401 HydrophobicContact CB-CG2 4.18Å; A217-I401 HydrophobicContact CB-CG2 4.01Å; L397-I401 HydrophobicContact CB-CD1 4.33Å; L397-I401 WeakPolarHBondContact O-CB 3.49Å; L397-I401 WeakPolarHBondContact O-CD1 3.45Å; L397-I401 WeakPolarHBondContact O-CG1 3.42Å; L397-I401 PolarHBondContact O-N 3.18Å; K398-I401 PolarHBondContact O-N 3.42Å; I401-I404 PolarHBondContact O-N 3.45Å; I401-V405 HydrophobicContact CG2-CG2 4.05Å; I401-V405 VanDerWaalsContact O-CB 3.28Å; I401-V405 WeakPolarHBondContact O-CB 3.3Å; I401-V405 VanDerWaalsContact O-CG2 3.29Å; I401-V405 WeakPolarHBondContact O-CG2 3.48Å; I401-V405 PolarHBondContact O-N 3.14Å; I401-L466 HydrophobicContact CG1-CD1 4.3Å; I401-L466 HydrophobicContact CG1-CD2 4.14Å
402	R	96.5	Very high	90.4	Very high	0 Å²	0	26.8 Å²	26.8	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-58.5	-50.8	-179	-177.9	175.9	58.4	-122.8	-1.7	112.1	F225 E229 T243 E246 K398 T399 T406	F225-R402 HydrophobicContact CE1-CB 4.5Å; F225-R402 HydrophobicContact CZ-CB 4.4Å; E229-R402 HydrophobicContact CG-CG 4.21Å; E229-R402 WeakPolarHBondContact OE2-CD 3.4Å; E229-R402 IonicContact OE2-CZ 2.66Å; E229-R402 IonicContact OE2-NH1 3.84Å; E229-R402 PolarHBondContact OE2-NH1 2.88Å; T243-R402 VanDerWaalsContact CG2-NH1 3.33Å; T243-R402 PolarHBondContact OG1-NH1 3.3Å; E246-R402 VanDerWaalsContact CD-NE 3.32Å; E246-R402 IonicContact OE1-CZ 2.95Å; E246-R402 IonicContact OE1-NE 2.7Å; E246-R402 PolarHBondContact OE1-NE 2.92Å; E246-R402 IonicContact OE1-NH2 3.16Å; E246-R402 IonicContact OE2-CZ 2.77Å; E246-R402 IonicContact OE2-NE 2.85Å; E246-R402 PolarHBondContact OE2-NE 3.27Å; E246-R402 IonicContact OE2-NH2 3.14Å; E246-R402 PolarHBondContact OE2-NH2 3.22Å; K398-R402 WeakPolarHBondContact O-CB 3.29Å; K398-R402 PolarHBondContact O-N 2.91Å; T399-R402 PolarHBondContact O-N 2.69Å; T399-R402 PolarHBondContact OG1-NH2 2.81Å; T399-R402 VanDerWaalsContact OG1-NH2 3.11Å; R402-T406 WeakPolarHBondContact O-CB 3.42Å; R402-T406 VanDerWaalsContact O-CG2 3.32Å; R402-T406 WeakPolarHBondContact O-CG2 3.01Å; R402-T406 PolarHBondContact O-N 3.5Å; R402-T406 VanDerWaalsContact O-N 3.09Å; R402-T406 PolarHBondContact O-OG1 3.42Å
403	I	96.6	Very high	91	Very high	0 Å²	0	22.5 Å²	22.5	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-66	-48.4	179.8	-64.1	173.3	0	0	0	110.3	E246 F382 K385 L386 T399 V405 T406 R407	E246-I403 WeakPolarHBondContact OE1-CG1 3.35Å; F382-I403 HydrophobicContact CB-CG2 4.05Å; F382-I403 HydrophobicContact CD1-CD1 4.16Å; F382-I403 HydrophobicContact CD1-CG1 4.04Å; F382-I403 HydrophobicContact CD1-CG2 3.94Å; F382-I403 HydrophobicContact CG-CG2 4.21Å; K385-I403 HydrophobicContact CB-CD1 3.66Å; K385-I403 HydrophobicContact CD-CD1 4.29Å; L386-I403 HydrophobicContact CD1-CG2 3.88Å; L386-I403 HydrophobicContact CD2-CB 4.11Å; L386-I403 HydrophobicContact CD2-CD1 4.23Å; L386-I403 HydrophobicContact CD2-CG2 4.14Å; L386-I403 HydrophobicContact CG-CB 4.38Å; L386-I403 HydrophobicContact CG-CD1 4.06Å; L386-I403 HydrophobicContact CG-CG2 3.96Å; T399-I403 HydrophobicContact CG2-CD1 3.64Å; T399-I403 HydrophobicContact CG2-CG1 4.24Å; T399-I403 WeakPolarHBondContact O-CB 3.37Å; T399-I403 WeakPolarHBondContact O-CG1 3.48Å; T399-I403 PolarHBondContact O-N 2.81Å; I403-V405 PolarHBondContact O-N 3.32Å; I403-T406 PolarHBondContact O-N 2.82Å; I403-T406 PolarHBondContact O-OG1 3.49Å; I403-R407 HydrophobicContact CG2-CG 4.2Å; I403-R407 VanDerWaalsContact O-CB 3.27Å; I403-R407 WeakPolarHBondContact O-CB 3.03Å; I403-R407 VanDerWaalsContact O-CG 3.29Å; I403-R407 WeakPolarHBondContact O-CG 3.42Å; I403-R407 PolarHBondContact O-N 2.64Å
404	I	95.8	Very high	91.9	Very high	0 Å²	0	24 Å²	24	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-65.8	-44.2	-176.1	-67.4	177.2	0	0	0	111.6	L386 I400 I401 C408 M412 L427 L431 L466 L469 I470	L386-I404 HydrophobicContact CD2-CG1 4.44Å; I400-I404 HydrophobicContact CG2-CD1 3.78Å; I400-I404 WeakPolarHBondContact O-CB 3.48Å; I400-I404 WeakPolarHBondContact O-CG1 3.34Å; I400-I404 PolarHBondContact O-N 2.84Å; I401-I404 PolarHBondContact O-N 3.45Å; I404-C408 WeakPolarHBondContact O-CB 3.42Å; I404-C408 PolarHBondContact O-N 3.34Å; I404-C408 PolarHBondContact O-SG 3.39Å; I404-C408 VanDerWaalsContact O-SG 3.34Å; I404-M412 HydrophobicContact CB-CE 4.45Å; I404-M412 HydrophobicContact CG1-CE 4.11Å; I404-L427 HydrophobicContact CD1-CD2 4.49Å; I404-L431 HydrophobicContact CD1-CD1 3.67Å; I404-L466 HydrophobicContact CB-CD2 3.96Å; I404-L466 HydrophobicContact CD1-CB 4.17Å; I404-L466 HydrophobicContact CD1-CD2 4.11Å; I404-L466 HydrophobicContact CG2-CD2 3.97Å; I404-L469 HydrophobicContact CG2-CB 3.66Å; I404-L469 HydrophobicContact CG2-CD1 3.85Å; I404-L469 HydrophobicContact CG2-CG 4.42Å; I404-I470 HydrophobicContact CD1-CG2 4.07Å; I404-I470 HydrophobicContact CG1-CG2 4.31Å; I404-I470 HydrophobicContact CG2-CG2 3.98Å
405	V	94.8	Very high	92.9	Very high	8 Å²	8	18.3 Å²	18.3	5%	0.048	9%	0.091	C	C	.	.	H	α-helix	trans	-68.2	-34.9	179.6	172.7	0	0	0	0	112.4	A217 L218 F225 I401 I403 L469	A217-V405 HydrophobicContact CB-CG1 4.25Å; A217-V405 HydrophobicContact CB-CG2 4.25Å; L218-V405 HydrophobicContact CD2-CG1 4.2Å; L218-V405 HydrophobicContact CD2-CG2 4.1Å; L218-V405 HydrophobicContact CG-CG2 4.1Å; F225-V405 HydrophobicContact CD1-CB 4.38Å; F225-V405 HydrophobicContact CD1-CG1 3.89Å; F225-V405 HydrophobicContact CE1-CB 3.98Å; F225-V405 HydrophobicContact CE1-CG1 3.95Å; I401-V405 HydrophobicContact CG2-CG2 4.05Å; I401-V405 VanDerWaalsContact O-CB 3.28Å; I401-V405 WeakPolarHBondContact O-CB 3.3Å; I401-V405 VanDerWaalsContact O-CG2 3.29Å; I401-V405 WeakPolarHBondContact O-CG2 3.48Å; I401-V405 PolarHBondContact O-N 3.14Å; I403-V405 PolarHBondContact O-N 3.32Å; V405-L469 HydrophobicContact CG2-CD1 4Å
406	T	94.4	Very high	93.8	Very high	2 Å²	2	12.9 Å²	12.9	1%	0.012	7%	0.067	C	C	.	.	H	α-helix	trans	-83.1	-21.2	179.8	59.6	0	0	0	0	114	F225 R251 R402 I403	F225-T406 HydrophobicContact CD1-CG2 3.8Å; F225-T406 HydrophobicContact CE1-CG2 4.26Å; R251-T406 PolarHBondContact NH2-OG1 2.92Å; R402-T406 WeakPolarHBondContact O-CB 3.42Å; R402-T406 VanDerWaalsContact O-CG2 3.32Å; R402-T406 WeakPolarHBondContact O-CG2 3.01Å; R402-T406 PolarHBondContact O-N 3.5Å; R402-T406 VanDerWaalsContact O-N 3.09Å; R402-T406 PolarHBondContact O-OG1 3.42Å; I403-T406 PolarHBondContact O-N 2.82Å; I403-T406 PolarHBondContact O-OG1 3.49Å
407	R	94.4	Very high	94.2	Very high	2 Å²	2	16.5 Å²	16.5	1%	0.008	8%	0.082	C	C	.	.	H	α-helix	trans	-112.6	-12.7	-175.3	-52.2	-49.3	-68.8	-170.2	-5.2	115.6	F382 I403 E409 V410 D411 M412 I415	F382-R407 HydrophobicContact CD2-CG 4.25Å; F382-R407 HydrophobicContact CE2-CG 4.17Å; F382-R407 HydrophobicContact CG-CG 4.46Å; F382-R407 HydrophobicContact CZ-CG 4.3Å; I403-R407 HydrophobicContact CG2-CG 4.2Å; I403-R407 VanDerWaalsContact O-CB 3.27Å; I403-R407 WeakPolarHBondContact O-CB 3.03Å; I403-R407 VanDerWaalsContact O-CG 3.29Å; I403-R407 WeakPolarHBondContact O-CG 3.42Å; I403-R407 PolarHBondContact O-N 2.64Å; R407-E409 PolarHBondContact O-N 3.36Å; R407-V410 PolarHBondContact O-N 3.18Å; R407-D411 WeakPolarHBondContact CB-OD1 3.16Å; R407-D411 IonicContact CZ-OD1 2.75Å; R407-D411 IonicContact CZ-OD2 2.76Å; R407-D411 IonicContact NE-OD1 3.4Å; R407-D411 PolarHBondContact NE-OD1 3.2Å; R407-D411 IonicContact NE-OD2 2.69Å; R407-D411 IonicContact NH2-OD1 3.23Å; R407-D411 PolarHBondContact NH2-OD1 2.85Å; R407-D411 IonicContact NH2-OD2 3.05Å; R407-D411 PolarHBondContact NH2-OD2 2.96Å; R407-D411 PolarHBondContact O-N 2.92Å; R407-M412 HydrophobicContact CB-CE 3.84Å; R407-M412 WeakPolarHBondContact O-CB 3.1Å; R407-M412 PolarHBondContact O-N 3.33Å; R407-I415 HydrophobicContact CB-CD1 3.68Å; R407-I415 HydrophobicContact CG-CD1 3.88Å
408	C	94	Very high	94.6	Very high	0 Å²	0	17.4 Å²	17.4	0%	0	9%	0.086	C	C	.	.	T	Hydrogen-bonded Turn	trans	-61.5	-17.2	-179.5	65.4	0	0	0	0	115.3	T142 V143 I404 L469	T142-C408 PolarHBondContact N-O 3.43Å; T142-C408 PolarHBondContact OG1-O 3.1Å; V143-C408 HydrophobicContact CG2-CB 4.01Å; V143-C408 PolarHBondContact N-O 2.8Å; I404-C408 WeakPolarHBondContact O-CB 3.42Å; I404-C408 PolarHBondContact O-N 3.34Å; I404-C408 PolarHBondContact O-SG 3.39Å; I404-C408 VanDerWaalsContact O-SG 3.34Å; C408-L469 HydrophobicContact CB-CB 4.15Å
409	E	91.2	Very high	94.8	Very high	40 Å²	40	15.1 Å²	15.1	19%	0.187	8%	0.076	C	C	.	.	T	Hydrogen-bonded Turn	trans	-113.1	22	175.8	-67	172.3	-118	0	0	111.8	V143 P180 L181 R184 R407	V143-E409 HydrophobicContact CB-CG 3.92Å; V143-E409 HydrophobicContact CG1-CG 4.48Å; P180-E409 WeakPolarHBondContact CA-OE2 3.5Å; P180-E409 HydrophobicContact CB-CG 4.48Å; P180-E409 WeakPolarHBondContact CB-OE2 3.41Å; L181-E409 WeakPolarHBondContact CB-OE2 3.36Å; L181-E409 VanDerWaalsContact N-CD 3.32Å; L181-E409 PolarHBondContact N-OE1 2.91Å; L181-E409 VanDerWaalsContact N-OE1 3.13Å; L181-E409 PolarHBondContact N-OE2 2.81Å; R184-E409 IonicContact CZ-OE1 3.14Å; R184-E409 VanDerWaalsContact CZ-OE1 3.23Å; R184-E409 IonicContact NH1-OE1 3.36Å; R184-E409 PolarHBondContact NH1-OE1 2.96Å; R184-E409 IonicContact NH2-OE1 2.73Å; R184-E409 PolarHBondContact NH2-OE1 2.73Å; R407-E409 PolarHBondContact O-N 3.36Å
410	V	91.1	Very high	94.9	Very high	5 Å²	5	18.7 Å²	18.7	3%	0.03	10%	0.095	C	C	.	.	T	Hydrogen-bonded Turn	trans	-131.8	-85	-179.7	-168.2	0	0	0	0	111.2	I139 T140 R407	I139-V410 CarbonylContact C-O 3.27Å; I139-V410 WeakPolarHBondContact CA-O 3.39Å; I139-V410 VanDerWaalsContact CG2-O 3.27Å; I139-V410 WeakPolarHBondContact CG2-O 3.46Å; T140-V410 CarbonylContact C-O 3.51Å; T140-V410 PolarHBondContact N-O 3.24Å; R407-V410 PolarHBondContact O-N 3.18Å
411	D	92.8	Very high	95	Very high	5 Å²	5	24.7 Å²	24.7	3%	0.027	13%	0.127	C	C	.	.	T	Hydrogen-bonded Turn	trans	-132.5	18.4	-165.5	57.8	-16.5	0	0	0	113.1	T140 R407 G413 Q414 I415	T140-D411 WeakPolarHBondContact OG1-CA 3.5Å; R407-D411 WeakPolarHBondContact CB-OD1 3.16Å; R407-D411 IonicContact CZ-OD1 2.75Å; R407-D411 IonicContact CZ-OD2 2.76Å; R407-D411 IonicContact NE-OD1 3.4Å; R407-D411 PolarHBondContact NE-OD1 3.2Å; R407-D411 IonicContact NE-OD2 2.69Å; R407-D411 IonicContact NH2-OD1 3.23Å; R407-D411 PolarHBondContact NH2-OD1 2.85Å; R407-D411 IonicContact NH2-OD2 3.05Å; R407-D411 PolarHBondContact NH2-OD2 2.96Å; R407-D411 PolarHBondContact O-N 2.92Å; D411-G413 PolarHBondContact O-N 3.4Å; D411-G413 VanDerWaalsContact O-N 3.13Å; D411-Q414 PolarHBondContact O-N 3.11Å; D411-Q414 VanDerWaalsContact O-N 3.13Å; D411-I415 WeakPolarHBondContact O-CG1 3.34Å; D411-I415 PolarHBondContact O-N 3.22Å; D411-I415 WeakPolarHBondContact OD1-CD1 3.44Å
412	M	95	Very high	95	Very high	0 Å²	0	27.6 Å²	27.6	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-59	-25.2	-177.9	-176.4	57.2	52.2	0	0	114	T140 T142 I404 R407 I415 K416 L427 I470	T140-M412 PolarHBondContact O-N 3.01Å; T142-M412 HydrophobicContact CG2-CB 3.87Å; T142-M412 HydrophobicContact CG2-CG 3.61Å; T142-M412 WeakPolarHBondContact OG1-CG 3.4Å; I404-M412 HydrophobicContact CB-CE 4.45Å; I404-M412 HydrophobicContact CG1-CE 4.11Å; R407-M412 HydrophobicContact CB-CE 3.84Å; R407-M412 WeakPolarHBondContact O-CB 3.1Å; R407-M412 PolarHBondContact O-N 3.33Å; M412-I415 HydrophobicContact CE-CD1 4.21Å; M412-I415 HydrophobicContact SD-CB 4.41Å; M412-I415 HydrophobicContact SD-CG2 4.34Å; M412-K416 HydrophobicContact CG-CD 4.07Å; M412-K416 VanDerWaalsContact O-CD 3.24Å; M412-K416 WeakPolarHBondContact O-CD 3.31Å; M412-K416 WeakPolarHBondContact O-CG 3.29Å; M412-K416 PolarHBondContact O-N 3.33Å; M412-K416 VanDerWaalsContact O-N 3.14Å; M412-K416 HydrophobicContact SD-CD 4.27Å; M412-K416 HydrophobicContact SD-CG 4.12Å; M412-L427 HydrophobicContact SD-CD2 4.15Å; M412-I470 HydrophobicContact CG-CB 4.44Å; M412-I470 HydrophobicContact CG-CG2 4Å; M412-I470 HydrophobicContact SD-CG2 3.74Å
413	G	94.4	Very high	94.9	Very high	17 Å²	17	31.7 Å²	31.7	18%	0.175	16%	0.158	C	C	.	.	H	α-helix	trans	-59.7	-60.1	169.7	0	0	0	0	0	111.6	T140 D411 I415 K416 E417	T140-G413 PolarHBondContact O-N 2.98Å; D411-G413 PolarHBondContact O-N 3.4Å; D411-G413 VanDerWaalsContact O-N 3.13Å; G413-I415 VanDerWaalsContact C-N 3.3Å; G413-I415 PolarHBondContact O-N 2.89Å; G413-K416 WeakPolarHBondContact O-CB 3.45Å; G413-K416 PolarHBondContact O-N 3.31Å; G413-K416 VanDerWaalsContact O-N 3.08Å; G413-E417 PolarHBondContact O-N 2.96Å; G413-E417 VanDerWaalsContact O-N 3.12Å
414	Q	94.1	Very high	94.8	Very high	45 Å²	45	34.8 Å²	34.8	21%	0.21	19%	0.19	C	C	.	.	H	α-helix	trans	-59	-38.1	176.6	-68.9	-178.4	-61	0	0	113	I138 T140 P379 D411 K416 E417 E418	I138-Q414 PolarHBondContact O-OE1 2.85Å; I138-Q414 VanDerWaalsContact O-OE1 3.07Å; T140-Q414 HydrophobicContact CG2-CG 4.15Å; T140-Q414 PolarHBondContact OG1-N 2.75Å; P379-Q414 HydrophobicContact CB-CB 3.63Å; P379-Q414 HydrophobicContact CG-CB 3.7Å; P379-Q414 HydrophobicContact CG-CG 4.48Å; D411-Q414 PolarHBondContact O-N 3.11Å; D411-Q414 VanDerWaalsContact O-N 3.13Å; Q414-K416 VanDerWaalsContact C-N 3.26Å; Q414-K416 PolarHBondContact O-N 2.91Å; Q414-E417 PolarHBondContact O-N 2.99Å; Q414-E418 PolarHBondContact O-N 3.48Å
415	I	96.5	Very high	94.6	Very high	0 Å²	0	40.6 Å²	40.6	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-60	-38.1	177	-67.8	169.3	0	0	0	110.9	P379 F382 A383 L386 R407 D411 M412 G413 F419	P379-I415 HydrophobicContact CB-CG1 4.01Å; F382-I415 HydrophobicContact CB-CD1 3.78Å; F382-I415 HydrophobicContact CB-CG1 4.01Å; F382-I415 HydrophobicContact CB-CG2 4.21Å; F382-I415 HydrophobicContact CD2-CD1 3.9Å; F382-I415 HydrophobicContact CG-CD1 4.11Å; A383-I415 HydrophobicContact CB-CG2 4.49Å; L386-I415 HydrophobicContact CD1-CG2 3.62Å; R407-I415 HydrophobicContact CB-CD1 3.68Å; R407-I415 HydrophobicContact CG-CD1 3.88Å; D411-I415 WeakPolarHBondContact O-CG1 3.34Å; D411-I415 PolarHBondContact O-N 3.22Å; D411-I415 WeakPolarHBondContact OD1-CD1 3.44Å; M412-I415 HydrophobicContact CE-CD1 4.21Å; M412-I415 HydrophobicContact SD-CB 4.41Å; M412-I415 HydrophobicContact SD-CG2 4.34Å; G413-I415 VanDerWaalsContact C-N 3.3Å; G413-I415 PolarHBondContact O-N 2.89Å; I415-F419 WeakPolarHBondContact O-CB 3.4Å; I415-F419 PolarHBondContact O-N 3.22Å
416	K	96	Very high	94.6	Very high	28 Å²	28	41.4 Å²	41.4	12%	0.122	22%	0.221	C	C	.	.	H	α-helix	trans	-73.2	-35.1	177.6	-69.7	160.4	65.7	-165.7	0	112.6	T142 M412 G413 Q414 L420 L427 I470 E472	T142-K416 HydrophobicContact CG2-CD 4.21Å; M412-K416 HydrophobicContact CG-CD 4.07Å; M412-K416 VanDerWaalsContact O-CD 3.24Å; M412-K416 WeakPolarHBondContact O-CD 3.31Å; M412-K416 WeakPolarHBondContact O-CG 3.29Å; M412-K416 PolarHBondContact O-N 3.33Å; M412-K416 VanDerWaalsContact O-N 3.14Å; M412-K416 HydrophobicContact SD-CD 4.27Å; M412-K416 HydrophobicContact SD-CG 4.12Å; G413-K416 WeakPolarHBondContact O-CB 3.45Å; G413-K416 PolarHBondContact O-N 3.31Å; G413-K416 VanDerWaalsContact O-N 3.08Å; Q414-K416 VanDerWaalsContact C-N 3.26Å; Q414-K416 PolarHBondContact O-N 2.91Å; K416-L420 WeakPolarHBondContact O-CB 3.24Å; K416-L420 PolarHBondContact O-N 3.11Å; K416-L427 HydrophobicContact CG-CB 4.37Å; K416-L427 HydrophobicContact CG-CD2 3.99Å; K416-I470 HydrophobicContact CD-CB 4.15Å; K416-I470 PolarHBondContact NZ-O 3.17Å; K416-E472 IonicContact NZ-OE1 3.61Å; K416-E472 PolarHBondContact NZ-OE1 3.37Å; K416-E472 IonicContact NZ-OE2 2.74Å; K416-E472 PolarHBondContact NZ-OE2 3.31Å
417	E	95.9	Very high	94.5	Very high	120 Å²	120	41.3 Å²	41.3	56%	0.561	22%	0.221	S	C	*	.	H	α-helix	trans	-64.4	-51.3	173.9	-68.7	170	-179.9	0	0	110.7	G413 Q414 F419 L420 N421	G413-E417 PolarHBondContact O-N 2.96Å; G413-E417 VanDerWaalsContact O-N 3.12Å; Q414-E417 PolarHBondContact O-N 2.99Å; E417-F419 VanDerWaalsContact C-N 3.34Å; E417-F419 PolarHBondContact O-N 3.48Å; E417-L420 PolarHBondContact O-N 2.99Å; E417-N421 WeakPolarHBondContact O-CB 3.29Å; E417-N421 PolarHBondContact O-N 2.57Å; E417-N421 PolarHBondContact O-ND2 2.89Å
418	E	96.6	Very high	94.4	Very high	36 Å²	36	43.7 Å²	43.7	17%	0.168	23%	0.231	C	C	.	.	H	α-helix	trans	-60.6	-39.8	174.2	-73.6	-72.4	170.6	0	0	112.4	N377 P379 R380 A383 Q414 L420 N421 L422	N377-E418 PolarHBondContact ND2-OE1 3.44Å; P379-E418 HydrophobicContact CB-CG 4.29Å; R380-E418 HydrophobicContact CB-CB 4.27Å; R380-E418 HydrophobicContact CB-CG 3.94Å; R380-E418 WeakPolarHBondContact CG-OE2 3.46Å; R380-E418 IonicContact NH1-OE2 2.77Å; A383-E418 HydrophobicContact CB-CB 3.77Å; Q414-E418 PolarHBondContact O-N 3.48Å; E418-L420 PolarHBondContact O-N 2.94Å; E418-N421 PolarHBondContact O-N 3.28Å; E418-L422 VanDerWaalsContact O-CB 3.26Å; E418-L422 WeakPolarHBondContact O-CB 3.42Å; E418-L422 WeakPolarHBondContact O-CG 3.45Å; E418-L422 PolarHBondContact O-N 3.37Å
419	F	96.9	Very high	94.2	Very high	0 Å²	0	47 Å²	47	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-60.8	-45.2	175.6	-174.2	-73.1	0	0	0	111.6	A383 L386 I387 T390 I415 E417 L422 Y423 K425 L427 C430	A383-F419 HydrophobicContact CB-CB 3.99Å; L386-F419 HydrophobicContact CB-CD2 3.81Å; L386-F419 HydrophobicContact CB-CE2 3.78Å; I387-F419 HydrophobicContact CB-CE2 4.36Å; I387-F419 HydrophobicContact CD1-CD2 4.32Å; I387-F419 HydrophobicContact CG1-CD2 3.6Å; I387-F419 HydrophobicContact CG1-CE1 4.5Å; I387-F419 HydrophobicContact CG1-CE2 3.5Å; I387-F419 HydrophobicContact CG1-CG 4.16Å; I387-F419 HydrophobicContact CG1-CZ 3.98Å; T390-F419 HydrophobicContact CG2-CE2 4.45Å; T390-F419 HydrophobicContact CG2-CZ 4.44Å; I415-F419 WeakPolarHBondContact O-CB 3.4Å; I415-F419 PolarHBondContact O-N 3.22Å; E417-F419 VanDerWaalsContact C-N 3.34Å; E417-F419 PolarHBondContact O-N 3.48Å; F419-L422 PolarHBondContact O-N 3.15Å; F419-Y423 AromaticContact CE1-CD1 3.81Å; F419-Y423 HydrophobicContact CE1-CD1 3.81Å; F419-Y423 HydrophobicContact CZ-CD1 4.08Å; F419-Y423 VanDerWaalsContact O-CB 3.31Å; F419-Y423 WeakPolarHBondContact O-CB 3.41Å; F419-Y423 PolarHBondContact O-N 3.01Å; F419-K425 WeakPolarHBondContact CD1-O 3.47Å; F419-K425 WeakPolarHBondContact CE1-O 3.41Å; F419-L427 HydrophobicContact CD1-CB 3.91Å; F419-L427 HydrophobicContact CD2-CB 4.25Å; F419-L427 HydrophobicContact CD2-CD1 3.96Å; F419-L427 VanDerWaalsContact CE1-CA 3.49Å; F419-L427 HydrophobicContact CE1-CB 4.1Å; F419-L427 HydrophobicContact CE2-CB 4.42Å; F419-L427 HydrophobicContact CE2-CD1 3.61Å; F419-L427 HydrophobicContact CG-CB 4.01Å; F419-L427 HydrophobicContact CZ-CB 4.35Å; F419-L427 HydrophobicContact CZ-CD1 3.95Å; F419-C430 HydrophobicContact CE1-CB 4.46Å; F419-C430 HydrophobicContact CZ-CB 4.11Å
420	L	96.6	Very high	94.2	Very high	84 Å²	84	46.2 Å²	46.2	44%	0.44	25%	0.247	S	C	.	.	H	α-helix	trans	-64.6	-44.4	177.1	-179.8	61.8	0	0	0	111.3	K416 E417 E418 L422 G424	K416-L420 WeakPolarHBondContact O-CB 3.24Å; K416-L420 PolarHBondContact O-N 3.11Å; E417-L420 PolarHBondContact O-N 2.99Å; E418-L420 PolarHBondContact O-N 2.94Å; L420-L422 VanDerWaalsContact C-N 3.34Å; L420-L422 PolarHBondContact O-N 3.09Å; L420-G424 WeakPolarHBondContact O-CA 2.97Å; L420-G424 PolarHBondContact O-N 2.91Å
421	N	96.8	Very high	94	Very high	125 Å²	125	46 Å²	46	67%	0.668	25%	0.246	S	C	*	.	H	α-helix	trans	-62.6	-38.1	178.4	-67.7	-21.1	0	0	0	112.5	E417 E418	E417-N421 WeakPolarHBondContact O-CB 3.29Å; E417-N421 PolarHBondContact O-N 2.57Å; E417-N421 PolarHBondContact O-ND2 2.89Å; E418-N421 PolarHBondContact O-N 3.28Å
422	L	95.8	Very high	93.6	Very high	62 Å²	62	49.6 Å²	49.6	33%	0.325	26%	0.262	S	S	.	.	H	α-helix	trans	-79.1	-34.3	-179.7	-80.7	171.2	0	0	0	114.3	R380 A383 E384 I387 E418 F419 L420	R380-L422 HydrophobicContact CG-CD1 3.88Å; A383-L422 HydrophobicContact CB-CD1 4.1Å; E384-L422 HydrophobicContact CG-CD1 3.57Å; I387-L422 HydrophobicContact CD1-CB 3.45Å; I387-L422 VanDerWaalsContact CD1-CB 3.45Å; I387-L422 HydrophobicContact CD1-CD1 3.89Å; I387-L422 HydrophobicContact CD1-CG 4.34Å; E418-L422 VanDerWaalsContact O-CB 3.26Å; E418-L422 WeakPolarHBondContact O-CB 3.42Å; E418-L422 WeakPolarHBondContact O-CG 3.45Å; E418-L422 PolarHBondContact O-N 3.37Å; F419-L422 PolarHBondContact O-N 3.15Å; L420-L422 VanDerWaalsContact C-N 3.34Å; L420-L422 PolarHBondContact O-N 3.09Å
423	Y	93.9	Very high	92.3	Very high	87 Å²	87	52.4 Å²	52.4	34%	0.341	27%	0.274	S	S	.	.	H	α-helix	trans	-116	-13.1	-167.4	-166.6	-128.9	0	0	0	114.7	I387 F419 K425 C430	I387-Y423 HydrophobicContact CG1-CG 4.27Å; I387-Y423 HydrophobicContact CG2-CD2 3.97Å; I387-Y423 HydrophobicContact CG2-CE2 4.4Å; I387-Y423 HydrophobicContact CG2-CG 4.32Å; F419-Y423 AromaticContact CE1-CD1 3.81Å; F419-Y423 HydrophobicContact CE1-CD1 3.81Å; F419-Y423 HydrophobicContact CZ-CD1 4.08Å; F419-Y423 VanDerWaalsContact O-CB 3.31Å; F419-Y423 WeakPolarHBondContact O-CB 3.41Å; F419-Y423 PolarHBondContact O-N 3.01Å; Y423-K425 HydrophobicContact CD1-CB 3.95Å; Y423-K425 HydrophobicContact CE1-CB 4.21Å; Y423-K425 HydrophobicContact CE1-CD 4.32Å; Y423-K425 PolarHBondContact O-N 3.4Å; Y423-K425 VanDerWaalsContact O-N 3.13Å; Y423-C430 VanDerWaalsContact CE1-SG 3.6Å
424	G	93.5	Very high	90.4	Very high	65 Å²	65	57.9 Å²	57.9	67%	0.67	30%	0.299	S	S	*	.	S	Bend	trans	68.9	3.6	-178.8	0	0	0	0	0	115	L420	L420-G424 WeakPolarHBondContact O-CA 2.97Å; L420-G424 PolarHBondContact O-N 2.91Å
425	K	92.3	Very high	87.9	Confident	122 Å²	122	59.1 Å²	59.1	53%	0.53	31%	0.307	S	S	.	.	S	Bend	trans	-129.1	147.5	171.4	-66.3	-173.3	175.8	-171.1	0	109.1	F419 Y423	F419-K425 WeakPolarHBondContact CD1-O 3.47Å; F419-K425 WeakPolarHBondContact CE1-O 3.41Å; Y423-K425 HydrophobicContact CD1-CB 3.95Å; Y423-K425 HydrophobicContact CE1-CB 4.21Å; Y423-K425 HydrophobicContact CE1-CD 4.32Å; Y423-K425 PolarHBondContact O-N 3.4Å; Y423-K425 VanDerWaalsContact O-N 3.13Å
426	S	93.8	Very high	85.1	Confident	24 Å²	24	62.3 Å²	62.3	17%	0.168	34%	0.34	C	S	.	.			trans	-72.1	151.4	177.4	82.5	0	0	0	0	111.6	K428 D429 C430	S426-K428 PolarHBondContact O-N 3.47Å; S426-K428 PolarHBondContact OG-N 2.82Å; S426-D429 WeakPolarHBondContact CB-OD2 3.48Å; S426-D429 PolarHBondContact O-N 3.46Å; S426-D429 VanDerWaalsContact O-N 3.11Å; S426-D429 PolarHBondContact OG-N 3.08Å; S426-D429 PolarHBondContact OG-OD2 2.96Å; S426-C430 PolarHBondContact O-N 3.38Å; S426-C430 VanDerWaalsContact O-N 3.15Å; S426-C430 PolarHBondContact O-SG 3.32Å
427	L	93.8	Very high	82.2	Confident	1 Å²	1	68.3 Å²	68.3	1%	0.005	36%	0.363	C	S	.	.	H	α-helix	trans	-56.4	-37	171.6	177.2	62.7	0	0	0	111.2	L386 T390 I404 M412 K416 F419 D429 C430 L431 I470	L386-L427 HydrophobicContact CB-CD1 4.35Å; L386-L427 HydrophobicContact CD1-CD1 4.25Å; L386-L427 HydrophobicContact CD1-CD2 3.94Å; L386-L427 HydrophobicContact CD2-CD1 4.49Å; T390-L427 HydrophobicContact CG2-CD1 4.26Å; I404-L427 HydrophobicContact CD1-CD2 4.49Å; M412-L427 HydrophobicContact SD-CD2 4.15Å; K416-L427 HydrophobicContact CG-CB 4.37Å; K416-L427 HydrophobicContact CG-CD2 3.99Å; F419-L427 HydrophobicContact CD1-CB 3.91Å; F419-L427 HydrophobicContact CD2-CB 4.25Å; F419-L427 HydrophobicContact CD2-CD1 3.96Å; F419-L427 VanDerWaalsContact CE1-CA 3.49Å; F419-L427 HydrophobicContact CE1-CB 4.1Å; F419-L427 HydrophobicContact CE2-CB 4.42Å; F419-L427 HydrophobicContact CE2-CD1 3.61Å; F419-L427 HydrophobicContact CG-CB 4.01Å; F419-L427 HydrophobicContact CZ-CB 4.35Å; F419-L427 HydrophobicContact CZ-CD1 3.95Å; L427-D429 PolarHBondContact O-N 2.86Å; L427-C430 PolarHBondContact O-N 3.43Å; L427-L431 HydrophobicContact CD1-CD1 4Å; L427-L431 HydrophobicContact CD1-CG 4.21Å; L427-L431 HydrophobicContact CG-CD1 3.96Å; L427-L431 VanDerWaalsContact O-CG 3.31Å; L427-L431 WeakPolarHBondContact O-CG 3.48Å; L427-L431 PolarHBondContact O-N 3.13Å; L427-I470 HydrophobicContact CD2-CD1 4.37Å; L427-I470 HydrophobicContact CD2-CG2 4.24Å; L427-I470 HydrophobicContact CG-CD1 4.26Å
428	K	92.2	Very high	79.4	Confident	51 Å²	51	70.7 Å²	70.7	22%	0.222	38%	0.379	C	S	.	.	H	α-helix	trans	-58.6	-45.9	175	162.6	167.1	174.3	179.9	0	112.2	S426 C430 L431 K432 L467 I470 E472	S426-K428 PolarHBondContact O-N 3.47Å; S426-K428 PolarHBondContact OG-N 2.82Å; K428-C430 VanDerWaalsContact C-N 3.32Å; K428-C430 PolarHBondContact O-N 3.13Å; K428-L431 PolarHBondContact O-N 2.97Å; K428-K432 WeakPolarHBondContact O-CG 3.43Å; K428-K432 PolarHBondContact O-N 2.96Å; K428-L467 HydrophobicContact CB-CD2 4.3Å; K428-L467 HydrophobicContact CG-CD2 4.04Å; K428-I470 HydrophobicContact CB-CD1 4.05Å; K428-E472 HydrophobicContact CD-CB 3.44Å; K428-E472 VanDerWaalsContact CD-CB 3.44Å; K428-E472 WeakPolarHBondContact CD-O 3.46Å; K428-E472 WeakPolarHBondContact CE-O 3.42Å; K428-E472 PolarHBondContact NZ-O 3.08Å; K428-E472 PolarHBondContact NZ-OXT 2.85Å
429	D	90	Very high	77	Confident	70 Å²	70	71.9 Å²	71.9	37%	0.374	39%	0.389	S	S	.	.	H	α-helix	trans	-69.4	-32.7	-179.9	-59.1	-48.5	0	0	0	111.9	S426 L427 L431 K432	S426-D429 WeakPolarHBondContact CB-OD2 3.48Å; S426-D429 PolarHBondContact O-N 3.46Å; S426-D429 VanDerWaalsContact O-N 3.11Å; S426-D429 PolarHBondContact OG-N 3.08Å; S426-D429 PolarHBondContact OG-OD2 2.96Å; L427-D429 PolarHBondContact O-N 2.86Å; D429-L431 VanDerWaalsContact C-N 3.29Å; D429-L431 PolarHBondContact O-N 3.39Å; D429-K432 PolarHBondContact O-N 3.05Å; D429-K432 WeakPolarHBondContact OD1-CE 3.42Å; D429-K432 IonicContact OD1-NZ 3.76Å; D429-K432 PolarHBondContact OD1-NZ 3.37Å
430	C	89.3	Confident	74.9	Confident	23 Å²	23	76.5 Å²	76.5	16%	0.155	41%	0.414	C	S	.	.	H	α-helix	trans	-71.8	-21.3	174.1	-56.2	0	0	0	0	113.6	T390 F419 Y423 S426 L427 K428	T390-C430 HydrophobicContact CG2-CB 4.09Å; F419-C430 HydrophobicContact CE1-CB 4.46Å; F419-C430 HydrophobicContact CZ-CB 4.11Å; Y423-C430 VanDerWaalsContact CE1-SG 3.6Å; S426-C430 PolarHBondContact O-N 3.38Å; S426-C430 VanDerWaalsContact O-N 3.15Å; S426-C430 PolarHBondContact O-SG 3.32Å; L427-C430 PolarHBondContact O-N 3.43Å; K428-C430 VanDerWaalsContact C-N 3.32Å; K428-C430 PolarHBondContact O-N 3.13Å
431	L	88.5	Confident	72.9	Confident	0 Å²	0	80.4 Å²	80.4	0%	0	43%	0.429	C	S	.	.	H	α-helix	trans	-98.3	-13.6	176.3	-66.5	176.4	0	0	0	113.7	T390 I400 I404 L427 K428 D429 R463 L466 L467 I470	T390-L431 HydrophobicContact CG2-CD2 4.33Å; I400-L431 HydrophobicContact CD1-CD2 4.36Å; I400-L431 HydrophobicContact CG2-CD2 3.79Å; I404-L431 HydrophobicContact CD1-CD1 3.67Å; L427-L431 HydrophobicContact CD1-CD1 4Å; L427-L431 HydrophobicContact CD1-CG 4.21Å; L427-L431 HydrophobicContact CG-CD1 3.96Å; L427-L431 VanDerWaalsContact O-CG 3.31Å; L427-L431 WeakPolarHBondContact O-CG 3.48Å; L427-L431 PolarHBondContact O-N 3.13Å; K428-L431 PolarHBondContact O-N 2.97Å; D429-L431 VanDerWaalsContact C-N 3.29Å; D429-L431 PolarHBondContact O-N 3.39Å; L431-R463 WeakPolarHBondContact O-CB 3.41Å; L431-R463 WeakPolarHBondContact O-CD 3.43Å; L431-L466 HydrophobicContact CD1-CB 4.36Å; L431-L467 HydrophobicContact CB-CD2 3.93Å; L431-L467 HydrophobicContact CB-CG 4.27Å; L431-I470 HydrophobicContact CD1-CD1 4.19Å
432	K	84.3	Confident	71	Confident	82 Å²	82	81.1 Å²	81.1	36%	0.357	43%	0.429	S	S	.	.	S	Bend	trans	-61.3	154.3	167.1	-77.2	172.3	-171.4	165.8	0	110	K428 D429	K428-K432 WeakPolarHBondContact O-CG 3.43Å; K428-K432 PolarHBondContact O-N 2.96Å; D429-K432 PolarHBondContact O-N 3.05Å; D429-K432 WeakPolarHBondContact OD1-CE 3.42Å; D429-K432 IonicContact OD1-NZ 3.76Å; D429-K432 PolarHBondContact OD1-NZ 3.37Å
433	F	67.4	Low	69.3	Low	59 Å²	59	79.9 Å²	79.9	26%	0.259	43%	0.426	S	S	.	.			trans	-85.3	110.4	153.3	-98.9	-82.1	0	0	0	107.1	N435 L455 R460 R463	F433-N435 PolarHBondContact O-N 3.45Å; F433-L455 HydrophobicContact CE1-CD1 3.83Å; F433-L455 HydrophobicContact CZ-CD1 4.34Å; F433-R460 HydrophobicContact CD2-CB 4.37Å; F433-R460 HydrophobicContact CD2-CG 4.39Å; F433-R460 HydrophobicContact CE2-CB 4.2Å; F433-R463 VanDerWaalsContact CE2-CZ 3.49Å; F433-R463 VanDerWaalsContact CZ-CZ 3.5Å
434	D	53.5	Low	67.5	Low	131 Å²	131	77.3 Å²	77.3	70%	0.701	42%	0.417	S	S	*	.			trans	-66.3	113.9	162.5	-90.7	-21.9	0	0	0	108.1	G436	D434-G436 PolarHBondContact O-N 2.83Å
435	N	43.1	Very low	66	Low	72 Å²	72	80.2 Å²	80.2	39%	0.385	41%	0.414	S	S	.	.			trans	-73.4	56.4	158.2	-69.6	-7	0	0	0	108.1	F433 Y437	F433-N435 PolarHBondContact O-N 3.45Å; N435-Y437 PolarHBondContact O-N 3.46Å
436	G	36	Very low	64.8	Low	66 Å²	66	79.1 Å²	79.1	68%	0.68	41%	0.413	S	S	*	.			trans	-66.8	9.4	-164.5	0	0	0	0	0	116.1	D434	D434-G436 PolarHBondContact O-N 2.83Å
437	Y	35	Very low	63.3	Low	155 Å²	155	79.6 Å²	79.6	61%	0.608	41%	0.413	S	S	*	.			trans	-94.6	102.4	173	-80.3	-75.2	0	0	0	109.6	N435 V439 N444 I447	N435-Y437 PolarHBondContact O-N 3.46Å; Y437-V439 HydrophobicContact CD1-CG2 4.1Å; Y437-V439 HydrophobicContact CG-CG2 4.43Å; Y437-V439 PolarHBondContact O-N 3.31Å; Y437-N444 PolarHBondContact O-ND2 3.46Å; Y437-N444 VanDerWaalsContact O-ND2 3.17Å; Y437-I447 HydrophobicContact CD2-CD1 4.2Å; Y437-I447 HydrophobicContact CG-CD1 4.01Å
438	N	38.9	Very low	61.5	Low	170 Å²	170	82.7 Å²	82.7	91%	0.909	43%	0.427	S	S	*	.			trans	-72.2	70.4	167.4	-172	18.8	0	0	0	109.8
439	V	44.5	Very low	60.1	Low	61 Å²	61	83.5 Å²	83.5	37%	0.37	44%	0.439	S	S	.	.			trans	-130	149.9	-175.8	-168	0	0	0	0	107.5	Y437 S443 N444	Y437-V439 HydrophobicContact CD1-CG2 4.1Å; Y437-V439 HydrophobicContact CG-CG2 4.43Å; Y437-V439 PolarHBondContact O-N 3.31Å; V439-S443 VanDerWaalsContact CG1-CB 3.42Å; V439-N444 PolarHBondContact O-ND2 2.81Å
440	N	52.9	Low	58.8	Low	97 Å²	97	83.9 Å²	83.9	52%	0.519	44%	0.441	S	S	.	.			trans	-49.6	153.7	-172.5	58.1	2.8	0	0	0	114.5	E442 S443 N444	N440-E442 PolarHBondContact O-N 3.28Å; N440-E442 VanDerWaalsContact O-N 3.08Å; N440-S443 WeakPolarHBondContact O-CA 3.23Å; N440-S443 WeakPolarHBondContact O-CB 3.46Å; N440-S443 PolarHBondContact O-N 3.31Å; N440-S443 WeakPolarHBondContact OD1-CB 3.48Å; N440-S443 PolarHBondContact OD1-OG 2.77Å; N440-N444 PolarHBondContact O-N 3.05Å
441	E	54.2	Low	57.1	Low	165 Å²	165	85.2 Å²	85.2	77%	0.771	45%	0.446	S	S	*	.	H	α-helix	trans	-51	-39.1	-170.5	-95.1	-172.5	131.7	0	0	114	N444 Q445	E441-N444 CarbonylContact O-C 3.55Å; E441-N444 WeakPolarHBondContact O-CB 3.24Å; E441-N444 PolarHBondContact O-N 2.69Å; E441-Q445 WeakPolarHBondContact O-CG 3.37Å; E441-Q445 PolarHBondContact O-N 3.11Å
442	E	58.3	Low	55.6	Low	140 Å²	140	90.7 Å²	90.7	65%	0.654	47%	0.472	S	S	*	.	H	α-helix	trans	-62.3	-48.1	176.3	-59.3	-179.7	142.4	0	0	111.8	N440 N444 Q445 I446	N440-E442 PolarHBondContact O-N 3.28Å; N440-E442 VanDerWaalsContact O-N 3.08Å; E442-N444 PolarHBondContact O-N 2.93Å; E442-Q445 WeakPolarHBondContact O-CB 3.31Å; E442-Q445 PolarHBondContact O-N 2.66Å; E442-Q445 VanDerWaalsContact O-N 3.08Å; E442-I446 WeakPolarHBondContact O-CG1 3.32Å; E442-I446 PolarHBondContact O-N 3.11Å
443	S	60.1	Low	54.3	Low	37 Å²	37	93.1 Å²	93.1	26%	0.259	49%	0.487	S	S	.	.	H	α-helix	trans	-63.2	-33.8	173.9	-61.7	0	0	0	0	111.4	V439 N440 Q445 I446 I447	V439-S443 VanDerWaalsContact CG1-CB 3.42Å; N440-S443 WeakPolarHBondContact O-CA 3.23Å; N440-S443 WeakPolarHBondContact O-CB 3.46Å; N440-S443 PolarHBondContact O-N 3.31Å; N440-S443 WeakPolarHBondContact OD1-CB 3.48Å; N440-S443 PolarHBondContact OD1-OG 2.77Å; S443-Q445 VanDerWaalsContact C-N 3.33Å; S443-I446 PolarHBondContact O-N 3.18Å; S443-I447 VanDerWaalsContact O-CB 3.31Å; S443-I447 WeakPolarHBondContact O-CB 3.41Å; S443-I447 WeakPolarHBondContact O-CG1 3.39Å; S443-I447 PolarHBondContact O-N 3.49Å
444	N	56.2	Low	53.6	Low	32 Å²	32	96.4 Å²	96.4	17%	0.171	51%	0.507	C	S	.	.	H	α-helix	trans	-68.2	-29.5	174.2	-111.9	-63.9	0	0	0	112.7	Y437 V439 N440 E441 E442 Q448	Y437-N444 PolarHBondContact O-ND2 3.46Å; Y437-N444 VanDerWaalsContact O-ND2 3.17Å; V439-N444 PolarHBondContact O-ND2 2.81Å; N440-N444 PolarHBondContact O-N 3.05Å; E441-N444 CarbonylContact O-C 3.55Å; E441-N444 WeakPolarHBondContact O-CB 3.24Å; E441-N444 PolarHBondContact O-N 2.69Å; E442-N444 PolarHBondContact O-N 2.93Å; N444-Q448 VanDerWaalsContact O-CB 3.3Å; N444-Q448 WeakPolarHBondContact O-CB 3.39Å; N444-Q448 WeakPolarHBondContact O-CG 3.44Å; N444-Q448 PolarHBondContact O-N 2.97Å; N444-Q448 VanDerWaalsContact O-N 3.07Å; N444-Q448 PolarHBondContact O-NE2 2.88Å
445	Q	60.6	Low	53.5	Low	126 Å²	126	93.4 Å²	93.4	59%	0.589	49%	0.49	S	S	*	.	H	α-helix	trans	-74.3	-39.6	169.8	-68.4	178.6	37.3	0	0	112	E441 E442 S443 Q448 S449	E441-Q445 WeakPolarHBondContact O-CG 3.37Å; E441-Q445 PolarHBondContact O-N 3.11Å; E442-Q445 WeakPolarHBondContact O-CB 3.31Å; E442-Q445 PolarHBondContact O-N 2.66Å; E442-Q445 VanDerWaalsContact O-N 3.08Å; S443-Q445 VanDerWaalsContact C-N 3.33Å; Q445-Q448 PolarHBondContact O-N 3.46Å; Q445-S449 WeakPolarHBondContact O-CB 3.46Å; Q445-S449 PolarHBondContact O-N 3.24Å; Q445-S449 PolarHBondContact O-OG 3.06Å
446	I	67.7	Low	54.2	Low	100 Å²	100	91.4 Å²	91.4	51%	0.513	49%	0.486	S	S	.	.	H	α-helix	trans	-64.4	-48.7	175.6	-68	167.3	0	0	0	110.3	E442 S443 Q448 S449 I450	E442-I446 WeakPolarHBondContact O-CG1 3.32Å; E442-I446 PolarHBondContact O-N 3.11Å; S443-I446 PolarHBondContact O-N 3.18Å; I446-Q448 VanDerWaalsContact C-N 3.34Å; I446-Q448 PolarHBondContact O-N 3.21Å; I446-S449 WeakPolarHBondContact O-CB 3.48Å; I446-S449 PolarHBondContact O-N 2.88Å; I446-S449 VanDerWaalsContact O-N 3.11Å; I446-I450 HydrophobicContact CG2-CD1 3.65Å; I446-I450 HydrophobicContact CG2-CG1 4.3Å; I446-I450 WeakPolarHBondContact O-CB 3.11Å; I446-I450 VanDerWaalsContact O-CG1 3.31Å; I446-I450 WeakPolarHBondContact O-CG1 3.4Å; I446-I450 PolarHBondContact O-N 2.81Å
447	I	62.1	Low	55.9	Low	34 Å²	34	89.1 Å²	89.1	17%	0.174	46%	0.463	C	S	.	.	H	α-helix	trans	-61.4	-40.4	175.6	-69.5	165.3	0	0	0	111	Y437 S443 S449 I450 N451	Y437-I447 HydrophobicContact CD2-CD1 4.2Å; Y437-I447 HydrophobicContact CG-CD1 4.01Å; S443-I447 VanDerWaalsContact O-CB 3.31Å; S443-I447 WeakPolarHBondContact O-CB 3.41Å; S443-I447 WeakPolarHBondContact O-CG1 3.39Å; S443-I447 PolarHBondContact O-N 3.49Å; I447-S449 VanDerWaalsContact C-N 3.33Å; I447-S449 PolarHBondContact O-N 2.77Å; I447-I450 PolarHBondContact O-N 2.65Å; I447-N451 VanDerWaalsContact O-CB 3.25Å; I447-N451 WeakPolarHBondContact O-CB 3.4Å; I447-N451 PolarHBondContact O-N 3.26Å
448	Q	56	Low	58	Low	65 Å²	65	84.9 Å²	84.9	30%	0.304	45%	0.449	S	S	.	.	H	α-helix	trans	-64	-36.7	173.7	-81.9	177.5	81	0	0	113.1	N444 Q445 I446 H452	N444-Q448 VanDerWaalsContact O-CB 3.3Å; N444-Q448 WeakPolarHBondContact O-CB 3.39Å; N444-Q448 WeakPolarHBondContact O-CG 3.44Å; N444-Q448 PolarHBondContact O-N 2.97Å; N444-Q448 VanDerWaalsContact O-N 3.07Å; N444-Q448 PolarHBondContact O-NE2 2.88Å; Q445-Q448 PolarHBondContact O-N 3.46Å; I446-Q448 VanDerWaalsContact C-N 3.34Å; I446-Q448 PolarHBondContact O-N 3.21Å; Q448-H452 VanDerWaalsContact O-CB 3.25Å; Q448-H452 WeakPolarHBondContact O-CB 3.41Å; Q448-H452 PolarHBondContact O-N 3.01Å
449	S	62.8	Low	60	Low	68 Å²	68	77.4 Å²	77.4	48%	0.476	41%	0.411	S	S	.	.	H	α-helix	trans	-70.9	-45.5	177	-56.9	0	0	0	0	111.2	Q445 I446 I447 H452 I453	Q445-S449 WeakPolarHBondContact O-CB 3.46Å; Q445-S449 PolarHBondContact O-N 3.24Å; Q445-S449 PolarHBondContact O-OG 3.06Å; I446-S449 WeakPolarHBondContact O-CB 3.48Å; I446-S449 PolarHBondContact O-N 2.88Å; I446-S449 VanDerWaalsContact O-N 3.11Å; I447-S449 VanDerWaalsContact C-N 3.33Å; I447-S449 PolarHBondContact O-N 2.77Å; S449-H452 WeakPolarHBondContact O-CB 3.37Å; S449-H452 PolarHBondContact O-N 3.14Å; S449-I453 WeakPolarHBondContact O-CD1 3.44Å; S449-I453 VanDerWaalsContact O-CG1 3.26Å; S449-I453 WeakPolarHBondContact O-CG1 3.4Å; S449-I453 PolarHBondContact O-N 3.16Å
450	I	63	Low	62	Low	78 Å²	78	79.1 Å²	79.1	40%	0.4	41%	0.41	S	S	.	.	H	α-helix	trans	-59.9	-47.8	174.3	-70.8	173.5	0	0	0	110.4	I446 I447 H452 I453 L454	I446-I450 HydrophobicContact CG2-CD1 3.65Å; I446-I450 HydrophobicContact CG2-CG1 4.3Å; I446-I450 WeakPolarHBondContact O-CB 3.11Å; I446-I450 VanDerWaalsContact O-CG1 3.31Å; I446-I450 WeakPolarHBondContact O-CG1 3.4Å; I446-I450 PolarHBondContact O-N 2.81Å; I447-I450 PolarHBondContact O-N 2.65Å; I450-H452 VanDerWaalsContact C-N 3.32Å; I450-H452 PolarHBondContact O-N 3.36Å; I450-I453 CarbonylContact O-C 3.6Å; I450-I453 PolarHBondContact O-N 3.05Å; I450-L454 HydrophobicContact CG2-CD1 3.5Å; I450-L454 HydrophobicContact CG2-CG 4.01Å; I450-L454 WeakPolarHBondContact O-CB 3.26Å; I450-L454 WeakPolarHBondContact O-CG 3.33Å; I450-L454 PolarHBondContact O-N 3.33Å
451	N	54.4	Low	63.7	Low	52 Å²	52	75.3 Å²	75.3	28%	0.278	39%	0.39	S	S	.	.	H	α-helix	trans	-65.8	-33.7	177.8	-72	-10.1	0	0	0	112.5	I447 I453 L455	I447-N451 VanDerWaalsContact O-CB 3.25Å; I447-N451 WeakPolarHBondContact O-CB 3.4Å; I447-N451 PolarHBondContact O-N 3.26Å; N451-I453 VanDerWaalsContact C-N 3.27Å; N451-I453 PolarHBondContact O-N 3.27Å; N451-L455 HydrophobicContact CB-CD1 4.36Å; N451-L455 WeakPolarHBondContact O-CB 2.81Å; N451-L455 PolarHBondContact O-N 3.05Å
452	H	55.6	Low	65.4	Low	115 Å²	115	67.5 Å²	67.5	53%	0.532	35%	0.353	S	S	.	.	H	α-helix	trans	-66.3	-30	172.5	-172.9	-62.5	0	0	0	112.4	Q448 S449 I450	Q448-H452 VanDerWaalsContact O-CB 3.25Å; Q448-H452 WeakPolarHBondContact O-CB 3.41Å; Q448-H452 PolarHBondContact O-N 3.01Å; S449-H452 WeakPolarHBondContact O-CB 3.37Å; S449-H452 PolarHBondContact O-N 3.14Å; I450-H452 VanDerWaalsContact C-N 3.32Å; I450-H452 PolarHBondContact O-N 3.36Å
453	I	58.6	Low	67	Low	132 Å²	132	61.8 Å²	61.8	68%	0.677	33%	0.326	S	S	*	.	H	α-helix	trans	-84.1	-42.4	178	-68.5	163.3	0	0	0	111.6	S449 I450 N451	S449-I453 WeakPolarHBondContact O-CD1 3.44Å; S449-I453 VanDerWaalsContact O-CG1 3.26Å; S449-I453 WeakPolarHBondContact O-CG1 3.4Å; S449-I453 PolarHBondContact O-N 3.16Å; I450-I453 CarbonylContact O-C 3.6Å; I450-I453 PolarHBondContact O-N 3.05Å; N451-I453 VanDerWaalsContact C-N 3.27Å; N451-I453 PolarHBondContact O-N 3.27Å
454	L	51.3	Low	68.4	Low	129 Å²	129	62.4 Å²	62.4	68%	0.675	33%	0.33	S	S	*	.	H	α-helix	trans	-90	-39.6	-171.6	-64.6	-174.7	0	0	0	114.4	I450	I450-L454 HydrophobicContact CG2-CD1 3.5Å; I450-L454 HydrophobicContact CG2-CG 4.01Å; I450-L454 WeakPolarHBondContact O-CB 3.26Å; I450-L454 WeakPolarHBondContact O-CG 3.33Å; I450-L454 PolarHBondContact O-N 3.33Å
455	L	52.1	Low	70.2	Confident	68 Å²	68	60.9 Å²	60.9	36%	0.356	32%	0.322	S	S	.	.	T	Hydrogen-bonded Turn	trans	-99.8	0.1	-174.5	-57.8	178	0	0	0	113.2	F433 N451 A459	F433-L455 HydrophobicContact CE1-CD1 3.83Å; F433-L455 HydrophobicContact CZ-CD1 4.34Å; N451-L455 HydrophobicContact CB-CD1 4.36Å; N451-L455 WeakPolarHBondContact O-CB 2.81Å; N451-L455 PolarHBondContact O-N 3.05Å; L455-A459 WeakPolarHBondContact O-CB 3.42Å
456	G	58.3	Low	71.8	Confident	29 Å²	29	54.9 Å²	54.9	30%	0.299	29%	0.294	S	S	.	.	T	Hydrogen-bonded Turn	trans	72.9	128.1	178.4	0	0	0	0	0	113.9	E458 A459	G456-E458 PolarHBondContact O-N 2.86Å; G456-E458 VanDerWaalsContact O-N 3.11Å; G456-A459 PolarHBondContact O-N 3.01Å; G456-A459 VanDerWaalsContact O-N 3.1Å
457	G	72.2	Confident	73	Confident	18 Å²	18	51.6 Å²	51.6	19%	0.186	28%	0.277	C	S	.	.	H	α-helix	trans	-53.8	-32.6	172.9	0	0	0	0	0	112.9	A459 R460 N461	G457-A459 PolarHBondContact O-N 3.4Å; G457-R460 WeakPolarHBondContact O-CB 3.42Å; G457-R460 PolarHBondContact O-N 2.99Å; G457-N461 WeakPolarHBondContact O-CB 3.42Å; G457-N461 VanDerWaalsContact O-CG 3.27Å; G457-N461 PolarHBondContact O-N 3.05Å; G457-N461 PolarHBondContact O-ND2 3.45Å
458	E	78.1	Confident	74.4	Confident	67 Å²	67	54.1 Å²	54.1	31%	0.313	29%	0.287	S	S	.	.	H	α-helix	trans	-53.8	-47.1	174.8	-66.1	161.5	-144.6	0	0	113	N208 G209 F211 G456 R460 N461 C462	N208-E458 WeakPolarHBondContact CB-OE1 3.13Å; G209-E458 WeakPolarHBondContact CA-OE2 3.41Å; G209-E458 PolarHBondContact N-OE2 3.48Å; F211-E458 HydrophobicContact CB-CB 4.26Å; F211-E458 WeakPolarHBondContact CB-O 3.26Å; G456-E458 PolarHBondContact O-N 2.86Å; G456-E458 VanDerWaalsContact O-N 3.11Å; E458-R460 VanDerWaalsContact C-N 3.33Å; E458-R460 PolarHBondContact O-N 2.69Å; E458-N461 PolarHBondContact O-N 2.58Å; E458-C462 VanDerWaalsContact O-CB 3.31Å; E458-C462 WeakPolarHBondContact O-CB 3.5Å; E458-C462 PolarHBondContact O-N 3.06Å
459	A	82	Confident	76.2	Confident	13 Å²	13	51 Å²	51	11%	0.107	27%	0.273	C	S	.	.	H	α-helix	trans	-63.8	-40.2	179.6	0	0	0	0	0	111.8	L455 G456 G457 R463	L455-A459 WeakPolarHBondContact O-CB 3.42Å; G456-A459 PolarHBondContact O-N 3.01Å; G456-A459 VanDerWaalsContact O-N 3.1Å; G457-A459 PolarHBondContact O-N 3.4Å; A459-R463 WeakPolarHBondContact O-CG 3.48Å; A459-R463 PolarHBondContact O-N 3.27Å
460	R	84.6	Confident	77.6	Confident	97 Å²	97	47.8 Å²	47.8	37%	0.366	25%	0.25	S	S	.	.	H	α-helix	trans	-65.9	-41.4	175.3	-173.4	179.7	-176.9	172	4.6	111.8	F433 G457 E458 S464	F433-R460 HydrophobicContact CD2-CB 4.37Å; F433-R460 HydrophobicContact CD2-CG 4.39Å; F433-R460 HydrophobicContact CE2-CB 4.2Å; G457-R460 WeakPolarHBondContact O-CB 3.42Å; G457-R460 PolarHBondContact O-N 2.99Å; E458-R460 VanDerWaalsContact C-N 3.33Å; E458-R460 PolarHBondContact O-N 2.69Å; R460-S464 VanDerWaalsContact O-CB 3.29Å; R460-S464 WeakPolarHBondContact O-CB 3.25Å; R460-S464 PolarHBondContact O-N 2.8Å
461	N	89.2	Confident	78.4	Confident	17 Å²	17	48.7 Å²	48.7	9%	0.091	25%	0.248	C	C	.	.	H	α-helix	trans	-71.3	-37.5	178.5	-69.6	-30.8	0	0	0	112.1	E169 I173 F211 G457 E458 S464 M465	E169-N461 PolarHBondContact OE1-ND2 3.29Å; E169-N461 PolarHBondContact OE2-ND2 3.36Å; I173-N461 HydrophobicContact CD1-CB 4.21Å; F211-N461 HydrophobicContact CB-CB 4.2Å; F211-N461 HydrophobicContact CD1-CB 4Å; F211-N461 VanDerWaalsContact CD2-C 3.48Å; F211-N461 HydrophobicContact CD2-CB 3.62Å; F211-N461 HydrophobicContact CE1-CB 4.29Å; F211-N461 HydrophobicContact CE2-CB 3.91Å; F211-N461 HydrophobicContact CG-CB 3.66Å; F211-N461 HydrophobicContact CZ-CB 4.24Å; G457-N461 WeakPolarHBondContact O-CB 3.42Å; G457-N461 VanDerWaalsContact O-CG 3.27Å; G457-N461 PolarHBondContact O-N 3.05Å; G457-N461 PolarHBondContact O-ND2 3.45Å; E458-N461 PolarHBondContact O-N 2.58Å; N461-S464 CarbonylContact O-C 3.46Å; N461-S464 PolarHBondContact O-N 2.81Å; N461-M465 PolarHBondContact O-N 3.48Å
462	C	91.2	Very high	78.4	Confident	0 Å²	0	52.8 Å²	52.8	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-61.1	-53.6	172.1	-175.9	0	0	0	0	111.1	C210 F211 E458 S464 M465 L466	C210-C462 HydrophobicContact CB-CB 4.09Å; C210-C462 PolarHBondContact O-SG 3.3Å; C210-C462 VanDerWaalsContact O-SG 3.38Å; C210-C462 VanDerWaalsContact SG-CB 3.57Å; F211-C462 HydrophobicContact CB-CB 4.3Å; E458-C462 VanDerWaalsContact O-CB 3.31Å; E458-C462 WeakPolarHBondContact O-CB 3.5Å; E458-C462 PolarHBondContact O-N 3.06Å; C462-S464 VanDerWaalsContact C-N 3.26Å; C462-S464 PolarHBondContact O-N 3.11Å; C462-M465 WeakPolarHBondContact O-CB 3.25Å; C462-M465 PolarHBondContact O-N 2.8Å; C462-L466 WeakPolarHBondContact O-CG 3.3Å; C462-L466 PolarHBondContact O-N 3.45Å
463	R	90.1	Very high	79.6	Confident	20 Å²	20	49.7 Å²	49.7	8%	0.075	25%	0.252	C	S	.	.	H	α-helix	trans	-56.6	-41.1	174.4	-71	-173.2	-154.3	176.1	11.7	111.4	E394 L431 F433 A459 M465 L466 L467	E394-R463 IonicContact OE1-NH2 3.31Å; E394-R463 PolarHBondContact OE1-NH2 2.93Å; L431-R463 WeakPolarHBondContact O-CB 3.41Å; L431-R463 WeakPolarHBondContact O-CD 3.43Å; F433-R463 VanDerWaalsContact CE2-CZ 3.49Å; F433-R463 VanDerWaalsContact CZ-CZ 3.5Å; A459-R463 WeakPolarHBondContact O-CG 3.48Å; A459-R463 PolarHBondContact O-N 3.27Å; R463-M465 VanDerWaalsContact C-N 3.31Å; R463-M465 PolarHBondContact O-N 2.81Å; R463-L466 PolarHBondContact O-N 3.07Å; R463-L467 WeakPolarHBondContact O-CB 3.2Å; R463-L467 VanDerWaalsContact O-CG 3.29Å; R463-L467 WeakPolarHBondContact O-CG 3.31Å; R463-L467 PolarHBondContact O-N 2.6Å
464	S	90.8	Very high	80.7	Confident	50 Å²	50	45.3 Å²	45.3	35%	0.35	23%	0.23	S	C	.	.	H	α-helix	trans	-66	-25.2	174.8	-174.1	0	0	0	0	114.6	R460 N461 C462	R460-S464 VanDerWaalsContact O-CB 3.29Å; R460-S464 WeakPolarHBondContact O-CB 3.25Å; R460-S464 PolarHBondContact O-N 2.8Å; N461-S464 CarbonylContact O-C 3.46Å; N461-S464 PolarHBondContact O-N 2.81Å; C462-S464 VanDerWaalsContact C-N 3.26Å; C462-S464 PolarHBondContact O-N 3.11Å
465	M	92.9	Very high	82.3	Confident	0 Å²	0	40.7 Å²	40.7	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-75.3	-48.6	171.2	-175.4	68.7	88.4	0	0	110.5	I173 M176 G177 F211 L215 L218 N461 C462 R463 L467 K468 L469	I173-M465 HydrophobicContact CB-CE 4.35Å; I173-M465 HydrophobicContact CB-SD 4.4Å; I173-M465 HydrophobicContact CG1-CB 4.44Å; I173-M465 HydrophobicContact CG1-CE 3.89Å; I173-M465 HydrophobicContact CG1-SD 4.27Å; I173-M465 HydrophobicContact CG2-SD 4.13Å; M176-M465 HydrophobicContact CB-CE 3.96Å; G177-M465 WeakPolarHBondContact CA-SD 3.19Å; F211-M465 HydrophobicContact CE2-CE 4.11Å; L215-M465 HydrophobicContact CD1-CE 4.39Å; L215-M465 HydrophobicContact CD2-CE 3.34Å; L215-M465 HydrophobicContact CG-CE 3.62Å; L218-M465 HydrophobicContact CD1-CE 4.2Å; L218-M465 HydrophobicContact CD1-CG 3.91Å; L218-M465 HydrophobicContact CD1-SD 3.95Å; N461-M465 PolarHBondContact O-N 3.48Å; C462-M465 WeakPolarHBondContact O-CB 3.25Å; C462-M465 PolarHBondContact O-N 2.8Å; R463-M465 VanDerWaalsContact C-N 3.31Å; R463-M465 PolarHBondContact O-N 2.81Å; M465-L467 VanDerWaalsContact C-N 3.3Å; M465-L467 PolarHBondContact O-N 2.93Å; M465-K468 WeakPolarHBondContact O-CA 3.21Å; M465-K468 WeakPolarHBondContact O-CB 3.31Å; M465-K468 PolarHBondContact O-N 3.43Å; M465-L469 PolarHBondContact O-N 3.41Å; M465-L469 VanDerWaalsContact O-N 3.13Å
466	L	93.8	Very high	84.1	Confident	0 Å²	0	39.1 Å²	39.1	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-59.4	-41.3	-179	-63.5	164.2	0	0	0	111.5	L397 I400 I401 I404 L431 C462 R463 K468 L469 I470	L397-L466 HydrophobicContact CD2-CD1 4.36Å; I400-L466 HydrophobicContact CG2-CD1 3.81Å; I401-L466 HydrophobicContact CG1-CD1 4.3Å; I401-L466 HydrophobicContact CG1-CD2 4.14Å; I404-L466 HydrophobicContact CB-CD2 3.96Å; I404-L466 HydrophobicContact CD1-CB 4.17Å; I404-L466 HydrophobicContact CD1-CD2 4.11Å; I404-L466 HydrophobicContact CG2-CD2 3.97Å; L431-L466 HydrophobicContact CD1-CB 4.36Å; C462-L466 WeakPolarHBondContact O-CG 3.3Å; C462-L466 PolarHBondContact O-N 3.45Å; R463-L466 PolarHBondContact O-N 3.07Å; L466-K468 PolarHBondContact O-N 3.07Å; L466-L469 PolarHBondContact O-N 2.78Å; L466-L469 VanDerWaalsContact O-N 3.13Å; L466-I470 PolarHBondContact O-N 2.92Å; L466-I470 VanDerWaalsContact O-N 3.09Å
467	L	92.9	Very high	85.7	Confident	32 Å²	32	39.7 Å²	39.7	17%	0.168	19%	0.19	C	C	.	.	H	α-helix	trans	-57	-33.9	172.1	-74.4	171.5	0	0	0	113.1	K428 L431 R463 M465 I470 R471	K428-L467 HydrophobicContact CB-CD2 4.3Å; K428-L467 HydrophobicContact CG-CD2 4.04Å; L431-L467 HydrophobicContact CB-CD2 3.93Å; L431-L467 HydrophobicContact CB-CG 4.27Å; R463-L467 WeakPolarHBondContact O-CB 3.2Å; R463-L467 VanDerWaalsContact O-CG 3.29Å; R463-L467 WeakPolarHBondContact O-CG 3.31Å; R463-L467 PolarHBondContact O-N 2.6Å; M465-L467 VanDerWaalsContact C-N 3.3Å; M465-L467 PolarHBondContact O-N 2.93Å; L467-I470 HydrophobicContact CD2-CD1 4.25Å; L467-I470 WeakPolarHBondContact O-CG1 3.44Å; L467-R471 PolarHBondContact O-N 2.91Å
468	K	92.9	Very high	86.6	Confident	87 Å²	87	41.1 Å²	41.1	38%	0.378	19%	0.19	S	C	.	.	H	α-helix	trans	-75.1	-34.8	175.6	-68.5	-50.2	-159.7	155.9	0	113.3	I173 G177 H178 M465 L466 R471	I173-K468 HydrophobicContact CG2-CG 4.05Å; G177-K468 CarbonylContact O-C 3.58Å; G177-K468 WeakPolarHBondContact O-CB 3.27Å; H178-K468 VanDerWaalsContact NE2-CD 3.31Å; H178-K468 WeakPolarHBondContact NE2-CD 3.43Å; H178-K468 WeakPolarHBondContact NE2-CE 3.31Å; H178-K468 PolarHBondContact NE2-NZ 3.23Å; M465-K468 WeakPolarHBondContact O-CA 3.21Å; M465-K468 WeakPolarHBondContact O-CB 3.31Å; M465-K468 PolarHBondContact O-N 3.43Å; L466-K468 PolarHBondContact O-N 3.07Å; K468-R471 WeakPolarHBondContact O-CG 3.42Å; K468-R471 PolarHBondContact O-N 3.32Å
469	L	93.3	Very high	87.2	Confident	0 Å²	0	39.3 Å²	39.3	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-67.2	-35	175.1	-60.3	175.8	0	0	0	112.3	T142 V143 L218 I404 V405 C408 M465 L466 R471	T142-L469 VanDerWaalsContact CB-O 3.29Å; T142-L469 WeakPolarHBondContact CB-O 3.46Å; T142-L469 PolarHBondContact OG1-O 2.83Å; V143-L469 HydrophobicContact CG2-CD2 4.25Å; V143-L469 VanDerWaalsContact CG2-O 3.3Å; V143-L469 WeakPolarHBondContact CG2-O 3.37Å; L218-L469 HydrophobicContact CD1-CD1 4.19Å; L218-L469 HydrophobicContact CD1-CD2 4.25Å; L218-L469 HydrophobicContact CD2-CD1 3.88Å; L218-L469 HydrophobicContact CD2-CD2 3.7Å; L218-L469 HydrophobicContact CD2-CG 4.44Å; L218-L469 HydrophobicContact CG-CD1 4.34Å; I404-L469 HydrophobicContact CG2-CB 3.66Å; I404-L469 HydrophobicContact CG2-CD1 3.85Å; I404-L469 HydrophobicContact CG2-CG 4.42Å; V405-L469 HydrophobicContact CG2-CD1 4Å; C408-L469 HydrophobicContact CB-CB 4.15Å; M465-L469 PolarHBondContact O-N 3.41Å; M465-L469 VanDerWaalsContact O-N 3.13Å; L466-L469 PolarHBondContact O-N 2.78Å; L466-L469 VanDerWaalsContact O-N 3.13Å; L469-R471 VanDerWaalsContact C-N 3.26Å; L469-R471 PolarHBondContact O-N 3.08Å
470	I	92.7	Very high	87.6	Confident	0 Å²	0	41.3 Å²	41.3	0%	0	19%	0.187	C	C	.	.	T	Hydrogen-bonded Turn	trans	-83.5	0.5	174.2	71.6	168.9	0	0	0	114.2	T142 I404 M412 K416 L427 K428 L431 L466 L467 E472	T142-I470 WeakPolarHBondContact CG2-O 3.17Å; I404-I470 HydrophobicContact CD1-CG2 4.07Å; I404-I470 HydrophobicContact CG1-CG2 4.31Å; I404-I470 HydrophobicContact CG2-CG2 3.98Å; M412-I470 HydrophobicContact CG-CB 4.44Å; M412-I470 HydrophobicContact CG-CG2 4Å; M412-I470 HydrophobicContact SD-CG2 3.74Å; K416-I470 HydrophobicContact CD-CB 4.15Å; K416-I470 PolarHBondContact NZ-O 3.17Å; L427-I470 HydrophobicContact CD2-CD1 4.37Å; L427-I470 HydrophobicContact CD2-CG2 4.24Å; L427-I470 HydrophobicContact CG-CD1 4.26Å; K428-I470 HydrophobicContact CB-CD1 4.05Å; L431-I470 HydrophobicContact CD1-CD1 4.19Å; L466-I470 PolarHBondContact O-N 2.92Å; L466-I470 VanDerWaalsContact O-N 3.09Å; L467-I470 HydrophobicContact CD2-CD1 4.25Å; L467-I470 WeakPolarHBondContact O-CG1 3.44Å; I470-E472 PolarHBondContact O-N 3.07Å
471	R	78.8	Confident	87.9	Confident	97 Å²	97	36.7 Å²	36.7	37%	0.366	17%	0.172	S	C	.	.	T	Hydrogen-bonded Turn	trans	53.1	41	171.4	-82.4	-140.2	-170.2	135.1	-16.7	117.7	T142 T144 L467 K468 L469	T142-R471 WeakPolarHBondContact O-CD 3.46Å; T142-R471 WeakPolarHBondContact O-CG 3.48Å; T142-R471 PolarHBondContact O-NE 3.36Å; T142-R471 PolarHBondContact O-NH1 2.94Å; T144-R471 VanDerWaalsContact N-NH1 3.14Å; T144-R471 VanDerWaalsContact N-NH2 3.14Å; T144-R471 PolarHBondContact O-NH2 2.63Å; T144-R471 PolarHBondContact OG1-NH1 3.2Å; T144-R471 PolarHBondContact OG1-NH2 2.93Å; L467-R471 PolarHBondContact O-N 2.91Å; K468-R471 WeakPolarHBondContact O-CG 3.42Å; K468-R471 PolarHBondContact O-N 3.32Å; L469-R471 VanDerWaalsContact C-N 3.26Å; L469-R471 PolarHBondContact O-N 3.08Å
472	E	55.7	Low	87.7	Confident	137 Å²	137	38.5 Å²	38.5	64%	0.64	18%	0.18	S	C	*	.			trans	-137.4	0	172.4	-77.9	168.4	-163.6	0	0	114	K416 K428 I470	K416-E472 IonicContact NZ-OE1 3.61Å; K416-E472 PolarHBondContact NZ-OE1 3.37Å; K416-E472 IonicContact NZ-OE2 2.74Å; K416-E472 PolarHBondContact NZ-OE2 3.31Å; K428-E472 HydrophobicContact CD-CB 3.44Å; K428-E472 VanDerWaalsContact CD-CB 3.44Å; K428-E472 WeakPolarHBondContact CD-O 3.46Å; K428-E472 WeakPolarHBondContact CE-O 3.42Å; K428-E472 PolarHBondContact NZ-O 3.08Å; K428-E472 PolarHBondContact NZ-OXT 2.85Å; I470-E472 PolarHBondContact O-N 3.07Å

Retrieved 472 of 472 residues in 262.4 ms (Link to these results)

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