A0A3Q0KVE2_SCHMA Loading...

NADH:ubiquinone reductase (H(+)-translocating)

AlphaFold DB , UniProt , Accession A0A3Q0KVE2, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 486 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	48.3	Very low	54.6	Low	164 Å²	164	76.4 Å²	76.4	81%	0.808	42%	0.421	S	S	*	.				0	-65.9	0	-136.6	-98.9	-101	0	0	110.1	M3 V5	M1-M3 PolarHBondContact O-N 3.1Å; M1-V5 WeakPolarHBondContact O-CB 3.23Å; M1-V5 VanDerWaalsContact O-CG2 3.25Å; M1-V5 WeakPolarHBondContact O-CG2 3.27Å; M1-V5 PolarHBondContact O-N 3.05Å; M1-V5 VanDerWaalsContact O-N 3.09Å; M1-V5 HydrophobicContact SD-CG2 4.42Å
2	L	49.9	Very low	55	Low	141 Å²	141	77.7 Å²	77.7	74%	0.738	42%	0.419	S	S	*	.	H	α-helix	trans	-56.3	-50.2	176.8	-95.3	151.8	0	0	0	114.7	G4 V5 V6	L2-G4 PolarHBondContact O-N 2.99Å; L2-V5 PolarHBondContact O-N 3.03Å; L2-V6 HydrophobicContact CD2-CG2 4.34Å; L2-V6 VanDerWaalsContact O-CB 3.25Å; L2-V6 WeakPolarHBondContact O-CB 3.29Å; L2-V6 WeakPolarHBondContact O-CG2 3.37Å; L2-V6 PolarHBondContact O-N 3.46Å
3	M	49.3	Very low	55.2	Low	149 Å²	149	78.5 Å²	78.5	73%	0.734	42%	0.422	S	S	*	.	H	α-helix	trans	-64	-42.9	-175.4	-167.1	-172.1	138.6	0	0	113	M1 V6 L7	M1-M3 PolarHBondContact O-N 3.1Å; M3-V6 PolarHBondContact O-N 2.92Å; M3-L7 HydrophobicContact CE-CD1 4.36Å; M3-L7 VanDerWaalsContact O-CB 3.25Å; M3-L7 WeakPolarHBondContact O-CB 3.35Å; M3-L7 PolarHBondContact O-N 3.32Å
4	G	56.7	Low	55.2	Low	30 Å²	30	80.3 Å²	80.3	31%	0.309	43%	0.43	S	S	.	.	H	α-helix	trans	-68.9	-40.1	177.8	0	0	0	0	0	113.1	L2 L7 L8	L2-G4 PolarHBondContact O-N 2.99Å; G4-L7 PolarHBondContact O-N 3.02Å; G4-L8 WeakPolarHBondContact O-CB 3.29Å; G4-L8 PolarHBondContact O-N 3.48Å
5	V	56.6	Low	55.3	Low	55 Å²	55	75.5 Å²	75.5	33%	0.333	41%	0.406	S	S	.	.	H	α-helix	trans	-66.1	-41.8	174.9	169.5	0	0	0	0	111	M1 L2 S9 M59	M1-V5 WeakPolarHBondContact O-CB 3.23Å; M1-V5 VanDerWaalsContact O-CG2 3.25Å; M1-V5 WeakPolarHBondContact O-CG2 3.27Å; M1-V5 PolarHBondContact O-N 3.05Å; M1-V5 VanDerWaalsContact O-N 3.09Å; M1-V5 HydrophobicContact SD-CG2 4.42Å; L2-V5 PolarHBondContact O-N 3.03Å; V5-S9 WeakPolarHBondContact O-CB 3.2Å; V5-S9 PolarHBondContact O-N 3.17Å; V5-S9 PolarHBondContact O-OG 3.39Å; V5-M59 HydrophobicContact CB-CE 4.5Å; V5-M59 HydrophobicContact CG1-CE 4.09Å
6	V	56.2	Low	55.3	Low	66 Å²	66	75.5 Å²	75.5	40%	0.4	41%	0.409	S	S	.	.	H	α-helix	trans	-64.3	-45.8	176	169.4	0	0	0	0	110.2	L2 M3 L8 S9 L10	L2-V6 HydrophobicContact CD2-CG2 4.34Å; L2-V6 VanDerWaalsContact O-CB 3.25Å; L2-V6 WeakPolarHBondContact O-CB 3.29Å; L2-V6 WeakPolarHBondContact O-CG2 3.37Å; L2-V6 PolarHBondContact O-N 3.46Å; M3-V6 PolarHBondContact O-N 2.92Å; V6-L8 PolarHBondContact O-N 3.25Å; V6-S9 WeakPolarHBondContact CA-OG 3.31Å; V6-S9 CarbonylContact O-C 3.5Å; V6-S9 PolarHBondContact O-N 3.19Å; V6-S9 PolarHBondContact O-OG 3.21Å; V6-L10 HydrophobicContact CG1-CD1 3.94Å; V6-L10 HydrophobicContact CG1-CG 4.4Å; V6-L10 WeakPolarHBondContact O-CB 3.48Å; V6-L10 WeakPolarHBondContact O-CG 3.4Å; V6-L10 PolarHBondContact O-N 3.02Å
7	L	55.2	Low	55.1	Low	61 Å²	61	76.4 Å²	76.4	32%	0.319	41%	0.413	S	S	.	.	H	α-helix	trans	-66.5	-41.8	-178.5	-147.5	160.1	0	0	0	111	M3 G4 L10 I11 F83	M3-L7 HydrophobicContact CE-CD1 4.36Å; M3-L7 VanDerWaalsContact O-CB 3.25Å; M3-L7 WeakPolarHBondContact O-CB 3.35Å; M3-L7 PolarHBondContact O-N 3.32Å; G4-L7 PolarHBondContact O-N 3.02Å; L7-L10 PolarHBondContact O-N 3.14Å; L7-I11 HydrophobicContact CD2-CD1 3.45Å; L7-I11 VanDerWaalsContact CD2-CD1 3.45Å; L7-I11 HydrophobicContact CD2-CG1 3.99Å; L7-I11 WeakPolarHBondContact O-CD1 3.27Å; L7-I11 WeakPolarHBondContact O-CG1 3.12Å; L7-I11 PolarHBondContact O-N 3.39Å; L7-F83 HydrophobicContact CD1-CZ 4.15Å; L7-F83 HydrophobicContact CD2-CE2 4.44Å; L7-F83 HydrophobicContact CD2-CZ 3.98Å
8	L	56.7	Low	55	Low	4 Å²	4	73.2 Å²	73.2	2%	0.021	40%	0.396	C	S	.	.	H	α-helix	trans	-69.9	-31.8	172.6	-79.4	156.9	0	0	0	113.5	G4 V6 L10 I11 F12 L55 S58 M59 L62 F83	G4-L8 WeakPolarHBondContact O-CB 3.29Å; G4-L8 PolarHBondContact O-N 3.48Å; V6-L8 PolarHBondContact O-N 3.25Å; L8-L10 VanDerWaalsContact C-N 3.34Å; L8-I11 HydrophobicContact CD2-CD1 4.49Å; L8-I11 PolarHBondContact O-N 3.42Å; L8-F12 VanDerWaalsContact O-CB 3.23Å; L8-F12 WeakPolarHBondContact O-CB 3.17Å; L8-F12 PolarHBondContact O-N 2.87Å; L8-L55 HydrophobicContact CD2-CD2 3.96Å; L8-S58 VanDerWaalsContact CD2-OG 3.26Å; L8-S58 WeakPolarHBondContact CD2-OG 3.41Å; L8-M59 HydrophobicContact CB-CE 4.07Å; L8-M59 HydrophobicContact CB-CG 3.98Å; L8-M59 HydrophobicContact CB-SD 3.13Å; L8-M59 WeakPolarHBondContact CB-SD 3.48Å; L8-M59 HydrophobicContact CD1-CG 4.3Å; L8-M59 HydrophobicContact CD1-SD 3.34Å; L8-M59 WeakPolarHBondContact CD1-SD 3.25Å; L8-M59 HydrophobicContact CD2-CG 4.48Å; L8-M59 HydrophobicContact CD2-SD 4.35Å; L8-M59 HydrophobicContact CG-CG 4.48Å; L8-M59 HydrophobicContact CG-SD 3.74Å; L8-L62 HydrophobicContact CD1-CD1 3.29Å; L8-F83 HydrophobicContact CD1-CD2 4.35Å; L8-F83 HydrophobicContact CG-CE2 4.32Å
9	S	58.1	Low	54.9	Low	44 Å²	44	74.9 Å²	74.9	31%	0.308	40%	0.4	S	S	.	.	H	α-helix	trans	-68.4	-35.8	172.1	74.9	0	0	0	0	111.5	V5 V6 F12 I13	V5-S9 WeakPolarHBondContact O-CB 3.2Å; V5-S9 PolarHBondContact O-N 3.17Å; V5-S9 PolarHBondContact O-OG 3.39Å; V6-S9 WeakPolarHBondContact CA-OG 3.31Å; V6-S9 CarbonylContact O-C 3.5Å; V6-S9 PolarHBondContact O-N 3.19Å; V6-S9 PolarHBondContact O-OG 3.21Å; S9-F12 PolarHBondContact O-N 3.22Å; S9-I13 WeakPolarHBondContact O-CB 3.36Å; S9-I13 WeakPolarHBondContact O-CD1 3.38Å; S9-I13 WeakPolarHBondContact O-CG1 3.45Å; S9-I13 PolarHBondContact O-N 3.48Å
10	L	55.5	Low	54.7	Low	92 Å²	92	79.4 Å²	79.4	48%	0.482	42%	0.418	S	S	.	.	H	α-helix	trans	-68.8	-41.9	173	-76.7	169.3	0	0	0	110.6	V6 L7 L8 F12 I13 L14	V6-L10 HydrophobicContact CG1-CD1 3.94Å; V6-L10 HydrophobicContact CG1-CG 4.4Å; V6-L10 WeakPolarHBondContact O-CB 3.48Å; V6-L10 WeakPolarHBondContact O-CG 3.4Å; V6-L10 PolarHBondContact O-N 3.02Å; L7-L10 PolarHBondContact O-N 3.14Å; L8-L10 VanDerWaalsContact C-N 3.34Å; L10-F12 VanDerWaalsContact C-N 3.3Å; L10-F12 PolarHBondContact O-N 3.41Å; L10-I13 PolarHBondContact O-N 2.81Å; L10-L14 WeakPolarHBondContact O-CB 3.12Å; L10-L14 WeakPolarHBondContact O-CG 3.26Å; L10-L14 PolarHBondContact O-N 3.24Å
11	I	58.3	Low	54.7	Low	34 Å²	34	78 Å²	78	17%	0.174	42%	0.423	C	S	.	.	H	α-helix	trans	-66.2	-35.5	173.7	-59.3	158.2	0	0	0	110.4	L7 L8 L14 S15 L55	L7-I11 HydrophobicContact CD2-CD1 3.45Å; L7-I11 VanDerWaalsContact CD2-CD1 3.45Å; L7-I11 HydrophobicContact CD2-CG1 3.99Å; L7-I11 WeakPolarHBondContact O-CD1 3.27Å; L7-I11 WeakPolarHBondContact O-CG1 3.12Å; L7-I11 PolarHBondContact O-N 3.39Å; L8-I11 HydrophobicContact CD2-CD1 4.49Å; L8-I11 PolarHBondContact O-N 3.42Å; I11-L14 CarbonylContact O-C 3.53Å; I11-L14 PolarHBondContact O-N 2.84Å; I11-S15 WeakPolarHBondContact O-CB 3.4Å; I11-S15 PolarHBondContact O-N 3.12Å; I11-S15 PolarHBondContact O-OG 2.78Å; I11-L55 HydrophobicContact CB-CD2 3.94Å; I11-L55 HydrophobicContact CG2-CD1 3.74Å; I11-L55 HydrophobicContact CG2-CD2 3.34Å; I11-L55 HydrophobicContact CG2-CG 4.16Å
12	F	59.5	Low	54.9	Low	92 Å²	92	71.8 Å²	71.8	40%	0.404	40%	0.401	S	S	.	.	H	α-helix	trans	-64.6	-47.5	173.7	-173.7	-98.5	0	0	0	110.9	L8 S9 L10 L14 S15 V16 L55	L8-F12 VanDerWaalsContact O-CB 3.23Å; L8-F12 WeakPolarHBondContact O-CB 3.17Å; L8-F12 PolarHBondContact O-N 2.87Å; S9-F12 PolarHBondContact O-N 3.22Å; L10-F12 VanDerWaalsContact C-N 3.3Å; L10-F12 PolarHBondContact O-N 3.41Å; F12-L14 VanDerWaalsContact C-N 3.31Å; F12-L14 PolarHBondContact O-N 3.36Å; F12-S15 WeakPolarHBondContact CA-OG 3.47Å; F12-S15 CarbonylContact O-C 3.26Å; F12-S15 PolarHBondContact O-N 3.15Å; F12-S15 VanDerWaalsContact O-N 3.11Å; F12-S15 PolarHBondContact O-OG 3.21Å; F12-V16 HydrophobicContact CD1-CG2 4.14Å; F12-V16 HydrophobicContact CE1-CG2 3.83Å; F12-V16 HydrophobicContact CZ-CG2 4.14Å; F12-V16 VanDerWaalsContact O-CG2 3.31Å; F12-V16 WeakPolarHBondContact O-CG2 3.42Å; F12-V16 PolarHBondContact O-N 2.7Å; F12-L55 HydrophobicContact CD2-CB 4.46Å
13	I	57.3	Low	55	Low	89 Å²	89	68.7 Å²	68.7	46%	0.456	39%	0.388	S	S	.	.	H	α-helix	trans	-59.7	-44	174.5	-69.8	160.9	0	0	0	110.2	S9 L10 S15 V16 L17	S9-I13 WeakPolarHBondContact O-CB 3.36Å; S9-I13 WeakPolarHBondContact O-CD1 3.38Å; S9-I13 WeakPolarHBondContact O-CG1 3.45Å; S9-I13 PolarHBondContact O-N 3.48Å; L10-I13 PolarHBondContact O-N 2.81Å; I13-S15 VanDerWaalsContact C-N 3.35Å; I13-S15 PolarHBondContact O-N 3.09Å; I13-V16 PolarHBondContact O-N 2.85Å; I13-L17 HydrophobicContact CG2-CD1 3.99Å; I13-L17 VanDerWaalsContact O-CG 3.25Å; I13-L17 WeakPolarHBondContact O-CG 3.34Å; I13-L17 PolarHBondContact O-N 2.92Å
14	L	55.4	Low	55.2	Low	103 Å²	103	64.4 Å²	64.4	54%	0.539	37%	0.37	S	S	.	.	H	α-helix	trans	-61.9	-41.8	174.5	-72.4	167.8	0	0	0	111.1	L10 I11 F12 V16 L17 V18	L10-L14 WeakPolarHBondContact O-CB 3.12Å; L10-L14 WeakPolarHBondContact O-CG 3.26Å; L10-L14 PolarHBondContact O-N 3.24Å; I11-L14 CarbonylContact O-C 3.53Å; I11-L14 PolarHBondContact O-N 2.84Å; F12-L14 VanDerWaalsContact C-N 3.31Å; F12-L14 PolarHBondContact O-N 3.36Å; L14-V16 VanDerWaalsContact C-N 3.31Å; L14-V16 PolarHBondContact O-N 3.49Å; L14-L17 HydrophobicContact CD2-CD1 4.45Å; L14-L17 CarbonylContact O-C 3.55Å; L14-L17 WeakPolarHBondContact O-CA 3.49Å; L14-L17 WeakPolarHBondContact O-CB 3.35Å; L14-L17 PolarHBondContact O-N 3.47Å; L14-L17 VanDerWaalsContact O-N 3.14Å; L14-V18 WeakPolarHBondContact O-CG2 3.4Å; L14-V18 PolarHBondContact O-N 3.34Å
15	S	56.5	Low	55	Low	9 Å²	9	67 Å²	67	6%	0.063	38%	0.383	C	S	.	.	H	α-helix	trans	-67.5	-30.6	177	74.7	0	0	0	0	113.2	I11 F12 I13 V18 F19 L55	I11-S15 WeakPolarHBondContact O-CB 3.4Å; I11-S15 PolarHBondContact O-N 3.12Å; I11-S15 PolarHBondContact O-OG 2.78Å; F12-S15 WeakPolarHBondContact CA-OG 3.47Å; F12-S15 CarbonylContact O-C 3.26Å; F12-S15 PolarHBondContact O-N 3.15Å; F12-S15 VanDerWaalsContact O-N 3.11Å; F12-S15 PolarHBondContact O-OG 3.21Å; I13-S15 VanDerWaalsContact C-N 3.35Å; I13-S15 PolarHBondContact O-N 3.09Å; S15-V18 WeakPolarHBondContact O-CB 3.41Å; S15-V18 PolarHBondContact O-N 3.27Å; S15-F19 PolarHBondContact O-N 3.12Å; S15-L55 VanDerWaalsContact CB-CD1 3.43Å; S15-L55 WeakPolarHBondContact OG-CD1 3.45Å
16	V	56	Low	54.7	Low	75 Å²	75	71 Å²	71	46%	0.455	39%	0.393	S	S	.	.	H	α-helix	trans	-72.2	-37.3	172.4	172.8	0	0	0	0	109.9	F12 I13 L14 V18 F19	F12-V16 HydrophobicContact CD1-CG2 4.14Å; F12-V16 HydrophobicContact CE1-CG2 3.83Å; F12-V16 HydrophobicContact CZ-CG2 4.14Å; F12-V16 VanDerWaalsContact O-CG2 3.31Å; F12-V16 WeakPolarHBondContact O-CG2 3.42Å; F12-V16 PolarHBondContact O-N 2.7Å; I13-V16 PolarHBondContact O-N 2.85Å; L14-V16 VanDerWaalsContact C-N 3.31Å; L14-V16 PolarHBondContact O-N 3.49Å; V16-V18 VanDerWaalsContact C-N 3.27Å; V16-V18 PolarHBondContact O-N 3.22Å; V16-F19 PolarHBondContact O-N 3.45Å
17	L	50.8	Low	54.4	Low	91 Å²	91	71.9 Å²	71.9	48%	0.476	40%	0.402	S	S	.	.	H	α-helix	trans	-67.3	-29.4	171.5	-67.8	166	0	0	0	111.8	I13 L14 F19 Q20	I13-L17 HydrophobicContact CG2-CD1 3.99Å; I13-L17 VanDerWaalsContact O-CG 3.25Å; I13-L17 WeakPolarHBondContact O-CG 3.34Å; I13-L17 PolarHBondContact O-N 2.92Å; L14-L17 HydrophobicContact CD2-CD1 4.45Å; L14-L17 CarbonylContact O-C 3.55Å; L14-L17 WeakPolarHBondContact O-CA 3.49Å; L14-L17 WeakPolarHBondContact O-CB 3.35Å; L14-L17 PolarHBondContact O-N 3.47Å; L14-L17 VanDerWaalsContact O-N 3.14Å; L17-F19 PolarHBondContact O-N 3.21Å; L17-Q20 WeakPolarHBondContact O-CB 3.34Å; L17-Q20 PolarHBondContact O-N 3.38Å
18	V	53.1	Low	54	Low	18 Å²	18	74.2 Å²	74.2	11%	0.109	41%	0.414	C	S	.	.	H	α-helix	trans	-66.8	-21.9	176.9	163.1	0	0	0	0	112.9	L14 S15 V16 Q20 G21 F42	L14-V18 WeakPolarHBondContact O-CG2 3.4Å; L14-V18 PolarHBondContact O-N 3.34Å; S15-V18 WeakPolarHBondContact O-CB 3.41Å; S15-V18 PolarHBondContact O-N 3.27Å; V16-V18 VanDerWaalsContact C-N 3.27Å; V16-V18 PolarHBondContact O-N 3.22Å; V18-Q20 PolarHBondContact O-N 2.89Å; V18-Q20 VanDerWaalsContact O-N 3.1Å; V18-G21 PolarHBondContact O-N 2.92Å; V18-F42 HydrophobicContact CB-CB 4.44Å; V18-F42 HydrophobicContact CB-CD1 4.33Å; V18-F42 HydrophobicContact CG1-CB 3.9Å; V18-F42 HydrophobicContact CG1-CD1 4.1Å; V18-F42 HydrophobicContact CG2-CB 3.92Å; V18-F42 HydrophobicContact CG2-CD1 3.25Å; V18-F42 HydrophobicContact CG2-CE1 3.92Å; V18-F42 HydrophobicContact CG2-CG 3.83Å
19	F	53.1	Low	53.5	Low	106 Å²	106	76.2 Å²	76.2	47%	0.465	44%	0.436	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62	-15.3	169.1	-91.5	-83.7	0	0	0	113.5	S15 V16 L17 G21 L52	S15-F19 PolarHBondContact O-N 3.12Å; V16-F19 PolarHBondContact O-N 3.45Å; L17-F19 PolarHBondContact O-N 3.21Å; F19-G21 VanDerWaalsContact C-N 3.33Å; F19-L52 HydrophobicContact CE2-CD1 3.99Å; F19-L52 HydrophobicContact CZ-CD1 4.46Å
20	Q	52.2	Low	52.8	Low	165 Å²	165	80.4 Å²	80.4	77%	0.771	47%	0.466	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.5	-5.1	175.7	-61	-170.7	-31.3	0	0	113.8	L17 V18	L17-Q20 WeakPolarHBondContact O-CB 3.34Å; L17-Q20 PolarHBondContact O-N 3.38Å; V18-Q20 PolarHBondContact O-N 2.89Å; V18-Q20 VanDerWaalsContact O-N 3.1Å
21	G	53.1	Low	52.2	Low	51 Å²	51	79.2 Å²	79.2	53%	0.526	47%	0.469	S	S	.	.			trans	73.7	136	-178.4	0	0	0	0	0	112.5	V18 F19	V18-G21 PolarHBondContact O-N 2.92Å; F19-G21 VanDerWaalsContact C-N 3.33Å
22	G	52.7	Low	51.5	Low	33 Å²	33	85.2 Å²	85.2	34%	0.34	49%	0.49	S	S	.	.			trans	-173.3	153.1	176	0	0	0	0	0	111.1	F42	G22-F42 CarbonylContact O-C 3.46Å; G22-F42 WeakPolarHBondContact O-CA 3.41Å; G22-F42 VanDerWaalsContact O-CB 3.29Å; G22-F42 WeakPolarHBondContact O-CB 3.2Å; G22-F42 PolarHBondContact O-N 3.16Å
23	V	53.6	Low	50.8	Low	76 Å²	76	89.3 Å²	89.3	46%	0.461	52%	0.516	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-118.5	120.3	170.4	177	0	0	0	0	106.4	H41	V23-H41 WeakPolarHBondContact CG1-CE1 3.31Å; V23-H41 VanDerWaalsContact CG1-ND1 3.31Å; V23-H41 WeakPolarHBondContact CG1-ND1 3.27Å; V23-H41 WeakPolarHBondContact CG2-ND1 3.41Å
24	V	52.4	Low	50.4	Low	59 Å²	59	93.7 Å²	93.7	36%	0.358	53%	0.532	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-110.2	94.8	168.2	-172.6	0	0	0	0	106.3	Y26 L40 F42	V24-Y26 HydrophobicContact CB-CE2 4.2Å; V24-Y26 HydrophobicContact CG1-CD2 3.94Å; V24-Y26 HydrophobicContact CG1-CE1 4.28Å; V24-Y26 HydrophobicContact CG1-CE2 3.33Å; V24-L40 CarbonylContact C-O 3.47Å; V24-L40 PolarHBondContact N-O 2.93Å; V24-L40 PolarHBondContact O-N 3.45Å; V24-L40 VanDerWaalsContact O-O 3.05Å; V24-F42 HydrophobicContact CB-CD2 4.41Å; V24-F42 HydrophobicContact CB-CE2 4.08Å; V24-F42 HydrophobicContact CG2-CD2 4.11Å; V24-F42 HydrophobicContact CG2-CE2 3.97Å
25	S	52.6	Low	50.1	Low	84 Å²	84	93.8 Å²	93.8	59%	0.587	53%	0.528	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-78.8	120.2	170.8	45.5	0	0	0	0	109.3
26	Y	50.3	Low	49.9	Very low	139 Å²	139	95.9 Å²	95.9	55%	0.545	55%	0.551	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-101	106.8	166.8	-69.9	-80.4	0	0	0	107.5	V24 L28 M38 L40	V24-Y26 HydrophobicContact CB-CE2 4.2Å; V24-Y26 HydrophobicContact CG1-CD2 3.94Å; V24-Y26 HydrophobicContact CG1-CE1 4.28Å; V24-Y26 HydrophobicContact CG1-CE2 3.33Å; Y26-L28 PolarHBondContact O-N 3.08Å; Y26-M38 PolarHBondContact N-O 3.02Å; Y26-M38 CarbonylContact O-C 3.53Å; Y26-M38 PolarHBondContact O-N 3.38Å; Y26-M38 VanDerWaalsContact O-O 3.04Å; Y26-L40 HydrophobicContact CD2-CD1 4.04Å; Y26-L40 HydrophobicContact CD2-CG 4.33Å; Y26-L40 HydrophobicContact CE2-CD1 4Å
27	S	49.6	Very low	49.8	Very low	84 Å²	84	96.7 Å²	96.7	59%	0.587	55%	0.553	S	S	*	*			trans	-74.4	107.3	167.1	52.9	0	0	0	0	108.6	G29 D37	S27-G29 PolarHBondContact O-N 3.42Å; S27-D37 VanDerWaalsContact CA-OD1 3.27Å; S27-D37 WeakPolarHBondContact CA-OD1 3.19Å; S27-D37 WeakPolarHBondContact CB-OD1 3.47Å
28	L	47.5	Very low	49.8	Very low	110 Å²	110	94.2 Å²	94.2	58%	0.576	54%	0.539	S	S	*	.			trans	-75.8	74.3	165.5	-74.2	164.5	0	0	0	106.6	Y26 S30 M38	Y26-L28 PolarHBondContact O-N 3.08Å; L28-S30 PolarHBondContact O-N 3.27Å; L28-M38 HydrophobicContact CD1-CB 3.98Å; L28-M38 HydrophobicContact CD1-CG 3.66Å
29	G	45.5	Very low	49.9	Very low	46 Å²	46	93.9 Å²	93.9	47%	0.474	54%	0.538	S	S	.	.			trans	-47.1	136.6	-169	0	0	0	0	0	113.7	S27 A31	S27-G29 PolarHBondContact O-N 3.42Å; G29-A31 PolarHBondContact O-N 2.64Å
30	S	44.3	Very low	50	Low	133 Å²	133	90.7 Å²	90.7	93%	0.93	53%	0.525	S	S	*	.	S	Bend	trans	35.1	-0.1	169	71.2	0	0	0	0	121.7	L28	L28-S30 PolarHBondContact O-N 3.27Å
31	A	43.3	Very low	50.2	Low	67 Å²	67	85.2 Å²	85.2	55%	0.554	50%	0.5	S	S	*	.	S	Bend	trans	-86.2	-10.7	-171.4	0	0	0	0	0	113.3	G29	G29-A31 PolarHBondContact O-N 2.64Å
32	Y	42.3	Very low	50.3	Low	159 Å²	159	84.9 Å²	84.9	62%	0.624	48%	0.484	S	S	*	.			trans	-144.5	96.7	176.3	-53.9	-76.3	0	0	0	110.2	F34 F35	Y32-F34 PolarHBondContact O-N 3.07Å; Y32-F35 PolarHBondContact O-N 2.86Å; Y32-F35 VanDerWaalsContact O-N 3.07Å
33	L	45.7	Very low	50.3	Low	178 Å²	178	86.8 Å²	86.8	93%	0.932	49%	0.492	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.9	-7.9	176.1	-95.9	151.1	0	0	0	115.2
34	F	49.4	Very low	50.9	Low	181 Å²	181	84.5 Å²	84.5	79%	0.794	48%	0.479	S	S	*	.	T	Hydrogen-bonded Turn	trans	-106.3	-15	-179.5	-76.4	-79.8	0	0	0	114.4	Y32	Y32-F34 PolarHBondContact O-N 3.07Å
35	F	49.1	Very low	51.9	Low	106 Å²	106	84.3 Å²	84.3	47%	0.465	49%	0.49	S	S	.	.	S	Bend	trans	-111.1	116	178.2	-78.1	-90.4	0	0	0	107.9	Y32 V99	Y32-F35 PolarHBondContact O-N 2.86Å; Y32-F35 VanDerWaalsContact O-N 3.07Å; F35-V99 HydrophobicContact CD1-CG1 3.9Å; F35-V99 HydrophobicContact CE1-CG1 3.42Å; F35-V99 VanDerWaalsContact CE1-CG1 3.42Å; F35-V99 HydrophobicContact CZ-CG1 4.08Å
36	G	52.1	Low	53.2	Low	52 Å²	52	82.4 Å²	82.4	54%	0.536	47%	0.472	S	S	.	.			trans	-57.6	169	166.8	0	0	0	0	0	111.1	M38	G36-M38 PolarHBondContact O-N 2.85Å; G36-M38 VanDerWaalsContact O-N 3.1Å
37	D	53.5	Low	54.6	Low	93 Å²	93	75.9 Å²	75.9	50%	0.497	45%	0.447	S	S	.	.			trans	-50.8	121.2	173.6	-70.8	-30.6	0	0	0	109.4	S27 S39	S27-D37 VanDerWaalsContact CA-OD1 3.27Å; S27-D37 WeakPolarHBondContact CA-OD1 3.19Å; S27-D37 WeakPolarHBondContact CB-OD1 3.47Å; D37-S39 VanDerWaalsContact C-N 3.29Å; D37-S39 PolarHBondContact O-N 3.1Å
38	M	50.7	Low	55.8	Low	38 Å²	38	72.5 Å²	72.5	19%	0.187	42%	0.423	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-71.9	90.3	177.8	-76.4	-71.8	-68.3	0	0	108.4	Y26 L28 G36 L40	Y26-M38 PolarHBondContact N-O 3.02Å; Y26-M38 CarbonylContact O-C 3.53Å; Y26-M38 PolarHBondContact O-N 3.38Å; Y26-M38 VanDerWaalsContact O-O 3.04Å; L28-M38 HydrophobicContact CD1-CB 3.98Å; L28-M38 HydrophobicContact CD1-CG 3.66Å; G36-M38 PolarHBondContact O-N 2.85Å; G36-M38 VanDerWaalsContact O-N 3.1Å; M38-L40 PolarHBondContact O-N 3.4Å
39	S	55.6	Low	57.3	Low	12 Å²	12	67.6 Å²	67.6	8%	0.084	40%	0.398	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-81.9	116.1	175.6	55.3	0	0	0	0	110.8	D37 H41	D37-S39 VanDerWaalsContact C-N 3.29Å; D37-S39 PolarHBondContact O-N 3.1Å; S39-H41 VanDerWaalsContact CB-CD2 3.48Å; S39-H41 WeakPolarHBondContact CB-CD2 3.42Å; S39-H41 VanDerWaalsContact CB-NE2 3.29Å; S39-H41 WeakPolarHBondContact CB-NE2 3.33Å; S39-H41 PolarHBondContact O-N 3.38Å; S39-H41 PolarHBondContact OG-CD2 3.14Å; S39-H41 VanDerWaalsContact OG-CD2 3.22Å; S39-H41 PolarHBondContact OG-NE2 3.16Å; S39-H41 VanDerWaalsContact OG-NE2 3.17Å
40	L	54	Low	59.2	Low	38 Å²	38	65.5 Å²	65.5	20%	0.199	38%	0.376	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-86.4	99.4	167.7	-61.2	-179	0	0	0	107.6	V24 Y26 M38 F42 L94	V24-L40 CarbonylContact C-O 3.47Å; V24-L40 PolarHBondContact N-O 2.93Å; V24-L40 PolarHBondContact O-N 3.45Å; V24-L40 VanDerWaalsContact O-O 3.05Å; Y26-L40 HydrophobicContact CD2-CD1 4.04Å; Y26-L40 HydrophobicContact CD2-CG 4.33Å; Y26-L40 HydrophobicContact CE2-CD1 4Å; M38-L40 PolarHBondContact O-N 3.4Å; L40-F42 HydrophobicContact CB-CE2 3.9Å; L40-F42 HydrophobicContact CB-CZ 4.37Å; L40-L94 WeakPolarHBondContact CA-O 3.42Å; L40-L94 HydrophobicContact CD2-CB 4Å
41	H	56.7	Low	61	Low	51 Å²	51	59.4 Å²	59.4	24%	0.236	33%	0.333	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-89.1	113.2	176.2	-74.4	-86.9	0	0	0	108.9	V23 S39 S43 L94 Y96	V23-H41 WeakPolarHBondContact CG1-CE1 3.31Å; V23-H41 VanDerWaalsContact CG1-ND1 3.31Å; V23-H41 WeakPolarHBondContact CG1-ND1 3.27Å; V23-H41 WeakPolarHBondContact CG2-ND1 3.41Å; S39-H41 VanDerWaalsContact CB-CD2 3.48Å; S39-H41 WeakPolarHBondContact CB-CD2 3.42Å; S39-H41 VanDerWaalsContact CB-NE2 3.29Å; S39-H41 WeakPolarHBondContact CB-NE2 3.33Å; S39-H41 PolarHBondContact O-N 3.38Å; S39-H41 PolarHBondContact OG-CD2 3.14Å; S39-H41 VanDerWaalsContact OG-CD2 3.22Å; S39-H41 PolarHBondContact OG-NE2 3.16Å; S39-H41 VanDerWaalsContact OG-NE2 3.17Å; H41-S43 PolarHBondContact O-N 2.84Å; H41-L94 PolarHBondContact N-O 3.48Å; H41-Y96 HydrophobicContact CB-CG 4.43Å
42	F	54.8	Low	62.7	Low	43 Å²	43	58.3 Å²	58.3	19%	0.189	32%	0.317	C	S	.	.			trans	-92.5	20.7	175	-65.3	-86.4	0	0	0	111.7	V18 G22 V24 L40 L94	V18-F42 HydrophobicContact CB-CB 4.44Å; V18-F42 HydrophobicContact CB-CD1 4.33Å; V18-F42 HydrophobicContact CG1-CB 3.9Å; V18-F42 HydrophobicContact CG1-CD1 4.1Å; V18-F42 HydrophobicContact CG2-CB 3.92Å; V18-F42 HydrophobicContact CG2-CD1 3.25Å; V18-F42 HydrophobicContact CG2-CE1 3.92Å; V18-F42 HydrophobicContact CG2-CG 3.83Å; G22-F42 CarbonylContact O-C 3.46Å; G22-F42 WeakPolarHBondContact O-CA 3.41Å; G22-F42 VanDerWaalsContact O-CB 3.29Å; G22-F42 WeakPolarHBondContact O-CB 3.2Å; G22-F42 PolarHBondContact O-N 3.16Å; V24-F42 HydrophobicContact CB-CD2 4.41Å; V24-F42 HydrophobicContact CB-CE2 4.08Å; V24-F42 HydrophobicContact CG2-CD2 4.11Å; V24-F42 HydrophobicContact CG2-CE2 3.97Å; L40-F42 HydrophobicContact CB-CE2 3.9Å; L40-F42 HydrophobicContact CB-CZ 4.37Å; F42-L94 HydrophobicContact CD1-CD2 3.26Å; F42-L94 HydrophobicContact CE1-CD1 3.63Å; F42-L94 HydrophobicContact CE1-CD2 3.15Å; F42-L94 HydrophobicContact CE1-CG 4Å; F42-L94 HydrophobicContact CG-CD2 4.26Å; F42-L94 HydrophobicContact CZ-CD1 3.98Å; F42-L94 HydrophobicContact CZ-CD2 4.03Å
43	S	53	Low	64.7	Low	73 Å²	73	50.7 Å²	50.7	51%	0.51	29%	0.288	S	S	.	.			trans	-108.1	-5.8	-163.2	62.8	0	0	0	0	115.8	H41	H41-S43 PolarHBondContact O-N 2.84Å
44	S	66.3	Low	66.7	Low	28 Å²	28	42.3 Å²	42.3	20%	0.196	24%	0.244	C	C	.	.			trans	-86.9	131.7	176.1	74.8	0	0	0	0	110.6	I46 S47 S48 E208	S44-I46 PolarHBondContact O-N 3.42Å; S44-I46 VanDerWaalsContact O-N 3.09Å; S44-S47 PolarHBondContact O-N 3.35Å; S44-S47 VanDerWaalsContact O-N 3.15Å; S44-S47 PolarHBondContact O-OG 2.89Å; S44-S47 VanDerWaalsContact OG-CB 3.27Å; S44-S47 WeakPolarHBondContact OG-CB 3.42Å; S44-S47 PolarHBondContact OG-N 3.31Å; S44-S47 PolarHBondContact OG-OG 2.83Å; S44-S48 PolarHBondContact O-N 3.48Å; S44-E208 PolarHBondContact OG-OE1 3.45Å
45	G	72.9	Confident	68.2	Low	56 Å²	56	33.8 Å²	33.8	58%	0.577	21%	0.207	S	C	*	.	H	α-helix	trans	-58.1	-21.7	171.8	0	0	0	0	0	112.9	S48 S49	G45-S48 PolarHBondContact O-OG 3.36Å; G45-S48 VanDerWaalsContact O-OG 3.12Å; G45-S49 PolarHBondContact O-N 3.27Å; G45-S49 PolarHBondContact O-OG 2.78Å
46	I	80.1	Confident	69.7	Low	44 Å²	44	30 Å²	30	23%	0.226	19%	0.193	C	C	.	.	H	α-helix	trans	-69.1	-53	174.7	-59.6	168.5	0	0	0	110.8	S44 S48 S49 M50 L207 E208 L275	S44-I46 PolarHBondContact O-N 3.42Å; S44-I46 VanDerWaalsContact O-N 3.09Å; I46-S48 PolarHBondContact O-N 3.19Å; I46-S49 PolarHBondContact O-OG 2.75Å; I46-M50 WeakPolarHBondContact O-CB 3.31Å; I46-M50 WeakPolarHBondContact O-CG 3.23Å; I46-M50 PolarHBondContact O-N 3.11Å; I46-M50 VanDerWaalsContact O-N 3.16Å; I46-L207 HydrophobicContact CD1-CB 4.48Å; I46-L207 HydrophobicContact CG2-CB 4.2Å; I46-L207 HydrophobicContact CG2-CD1 4.15Å; I46-E208 WeakPolarHBondContact CB-OE1 3.11Å; I46-E208 HydrophobicContact CG2-CG 4.44Å; I46-E208 VanDerWaalsContact CG2-OE1 3.31Å; I46-E208 WeakPolarHBondContact CG2-OE1 3.42Å; I46-L275 HydrophobicContact CB-CD1 3.95Å; I46-L275 HydrophobicContact CG1-CD1 3.89Å; I46-L275 HydrophobicContact CG2-CD1 3.82Å
47	S	79.2	Confident	71.4	Confident	1 Å²	1	27.6 Å²	27.6	1%	0.007	17%	0.168	C	C	.	.	H	α-helix	trans	-63.8	-40.2	-179.3	57.6	0	0	0	0	112.3	S44 M50 L51	S44-S47 PolarHBondContact O-N 3.35Å; S44-S47 VanDerWaalsContact O-N 3.15Å; S44-S47 PolarHBondContact O-OG 2.89Å; S44-S47 VanDerWaalsContact OG-CB 3.27Å; S44-S47 WeakPolarHBondContact OG-CB 3.42Å; S44-S47 PolarHBondContact OG-N 3.31Å; S44-S47 PolarHBondContact OG-OG 2.83Å; S47-M50 PolarHBondContact O-N 3.47Å; S47-L51 WeakPolarHBondContact O-CB 3.45Å; S47-L51 WeakPolarHBondContact O-CD1 3.43Å; S47-L51 WeakPolarHBondContact O-CG 3.43Å; S47-L51 PolarHBondContact O-N 3.45Å
48	S	75.5	Confident	72.9	Confident	14 Å²	14	23.2 Å²	23.2	10%	0.098	15%	0.145	C	C	.	.	H	α-helix	trans	-63.8	-44.6	-179	65.1	0	0	0	0	113	S44 G45 I46 L51 L52	S44-S48 PolarHBondContact O-N 3.48Å; G45-S48 PolarHBondContact O-OG 3.36Å; G45-S48 VanDerWaalsContact O-OG 3.12Å; I46-S48 PolarHBondContact O-N 3.19Å; S48-L51 PolarHBondContact O-N 3.06Å; S48-L52 PolarHBondContact O-N 3.37Å
49	S	79.5	Confident	74.3	Confident	7 Å²	7	23.8 Å²	23.8	5%	0.049	15%	0.147	C	C	.	.	H	α-helix	trans	-67.3	-38.5	177.7	56.7	0	0	0	0	112.5	G45 I46 L52 M53 L275	G45-S49 PolarHBondContact O-N 3.27Å; G45-S49 PolarHBondContact O-OG 2.78Å; I46-S49 PolarHBondContact O-OG 2.75Å; S49-L52 PolarHBondContact O-N 2.81Å; S49-M53 PolarHBondContact O-N 3.35Å; S49-M53 VanDerWaalsContact O-N 3.1Å; S49-L275 WeakPolarHBondContact OG-CD1 3.38Å; S49-L275 WeakPolarHBondContact OG-CD2 3.46Å
50	M	84.4	Confident	75.6	Confident	1 Å²	1	24.5 Å²	24.5	1%	0.005	15%	0.15	C	C	.	.	H	α-helix	trans	-64.8	-42.8	174.3	-72.7	-59.9	-61.8	0	0	112.7	I46 S47 M53 L54 V93 A200 W204 L278	I46-M50 WeakPolarHBondContact O-CB 3.31Å; I46-M50 WeakPolarHBondContact O-CG 3.23Å; I46-M50 PolarHBondContact O-N 3.11Å; I46-M50 VanDerWaalsContact O-N 3.16Å; S47-M50 PolarHBondContact O-N 3.47Å; M50-M53 HydrophobicContact CE-CE 3.56Å; M50-M53 PolarHBondContact O-N 3.41Å; M50-M53 HydrophobicContact SD-CE 4.11Å; M50-L54 WeakPolarHBondContact O-CB 3.4Å; M50-L54 PolarHBondContact O-N 2.7Å; M50-V93 HydrophobicContact CB-CG1 3.99Å; M50-A200 HydrophobicContact CE-CB 4.13Å; M50-W204 HydrophobicContact CE-CB 4.26Å; M50-L278 HydrophobicContact CE-CD2 3.68Å; M50-L278 HydrophobicContact SD-CD2 3.29Å; M50-L278 WeakPolarHBondContact SD-CD2 3.22Å
51	L	82.6	Confident	77.2	Confident	6 Å²	6	22.7 Å²	22.7	3%	0.031	14%	0.14	C	C	.	.	H	α-helix	trans	-62.6	-42.9	175.5	-73.8	162.9	0	0	0	111.3	S47 S48 M53 L54 L55 V90 V93 L94	S47-L51 WeakPolarHBondContact O-CB 3.45Å; S47-L51 WeakPolarHBondContact O-CD1 3.43Å; S47-L51 WeakPolarHBondContact O-CG 3.43Å; S47-L51 PolarHBondContact O-N 3.45Å; S48-L51 PolarHBondContact O-N 3.06Å; L51-M53 PolarHBondContact O-N 3.27Å; L51-L54 PolarHBondContact O-N 2.75Å; L51-L55 WeakPolarHBondContact O-CB 3.1Å; L51-L55 VanDerWaalsContact O-CG 3.22Å; L51-L55 WeakPolarHBondContact O-CG 3.45Å; L51-L55 PolarHBondContact O-N 3.43Å; L51-V90 HydrophobicContact CD2-CG1 4.08Å; L51-V90 HydrophobicContact CD2-CG2 4.46Å; L51-V93 HydrophobicContact CD1-CG1 4.41Å; L51-V93 HydrophobicContact CD2-CB 4.29Å; L51-V93 HydrophobicContact CD2-CG1 4.13Å; L51-V93 HydrophobicContact CG-CG1 3.81Å; L51-L94 HydrophobicContact CD1-CD2 3.48Å; L51-L94 VanDerWaalsContact CD1-CD2 3.48Å; L51-L94 HydrophobicContact CD1-CG 4.3Å; L51-L94 HydrophobicContact CD2-CD2 4.36Å; L51-L94 HydrophobicContact CD2-CG 4.31Å; L51-L94 HydrophobicContact CG-CD2 4.49Å
52	L	79.1	Confident	78.5	Confident	43 Å²	43	21 Å²	21	23%	0.225	13%	0.133	C	C	.	.	H	α-helix	trans	-59.1	-47.1	177.2	-180	134.9	0	0	0	111.5	F19 S48 S49 C56	F19-L52 HydrophobicContact CE2-CD1 3.99Å; F19-L52 HydrophobicContact CZ-CD1 4.46Å; S48-L52 PolarHBondContact O-N 3.37Å; S49-L52 PolarHBondContact O-N 2.81Å; L52-C56 WeakPolarHBondContact O-CB 3.41Å; L52-C56 PolarHBondContact O-N 3.45Å
53	M	84.9	Confident	79.8	Confident	0 Å²	0	21.3 Å²	21.3	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-57.4	-50.7	174.1	-178.5	-165.9	60.2	0	0	110.9	S49 M50 L51 L55 C56 C57 S196 A200 L278 V279 L283	S49-M53 PolarHBondContact O-N 3.35Å; S49-M53 VanDerWaalsContact O-N 3.1Å; M50-M53 HydrophobicContact CE-CE 3.56Å; M50-M53 PolarHBondContact O-N 3.41Å; M50-M53 HydrophobicContact SD-CE 4.11Å; L51-M53 PolarHBondContact O-N 3.27Å; M53-L55 PolarHBondContact O-N 3.02Å; M53-C56 PolarHBondContact O-N 2.89Å; M53-C57 WeakPolarHBondContact O-CB 3.32Å; M53-C57 PolarHBondContact O-N 3.38Å; M53-C57 PolarHBondContact O-SG 3.16Å; M53-C57 VanDerWaalsContact O-SG 3.33Å; M53-S196 WeakPolarHBondContact CE-O 3.27Å; M53-A200 HydrophobicContact CE-CB 4.28Å; M53-L278 HydrophobicContact CE-CD2 3.88Å; M53-L278 HydrophobicContact SD-CD2 3.88Å; M53-V279 HydrophobicContact CB-CG1 4.22Å; M53-V279 HydrophobicContact CB-CG2 4.41Å; M53-L283 HydrophobicContact CG-CG 4.35Å
54	L	87.5	Confident	81.3	Confident	2 Å²	2	17.9 Å²	17.9	1%	0.01	12%	0.116	C	C	.	.	H	α-helix	trans	-62.9	-44.8	-174.6	-176.9	127.2	0	0	0	112.8	M50 L51 C57 S58 M89 V90 T197	M50-L54 WeakPolarHBondContact O-CB 3.4Å; M50-L54 PolarHBondContact O-N 2.7Å; L51-L54 PolarHBondContact O-N 2.75Å; L54-C57 PolarHBondContact O-N 3.39Å; L54-S58 VanDerWaalsContact O-CB 3.25Å; L54-S58 WeakPolarHBondContact O-CB 3.36Å; L54-S58 PolarHBondContact O-N 2.94Å; L54-S58 PolarHBondContact O-OG 2.95Å; L54-M89 HydrophobicContact CD1-CB 3.66Å; L54-M89 HydrophobicContact CD1-CG 3.08Å; L54-V90 HydrophobicContact CD2-CG2 3.31Å; L54-T197 HydrophobicContact CD1-CG2 3.76Å
55	L	81.3	Confident	82.3	Confident	2 Å²	2	16.5 Å²	16.5	1%	0.01	11%	0.107	C	C	.	.	H	α-helix	trans	-67.3	-42.4	-178.4	-66.3	167.7	0	0	0	110.8	L8 I11 F12 S15 L51 M53 S58 M59 V90	L8-L55 HydrophobicContact CD2-CD2 3.96Å; I11-L55 HydrophobicContact CB-CD2 3.94Å; I11-L55 HydrophobicContact CG2-CD1 3.74Å; I11-L55 HydrophobicContact CG2-CD2 3.34Å; I11-L55 HydrophobicContact CG2-CG 4.16Å; F12-L55 HydrophobicContact CD2-CB 4.46Å; S15-L55 VanDerWaalsContact CB-CD1 3.43Å; S15-L55 WeakPolarHBondContact OG-CD1 3.45Å; L51-L55 WeakPolarHBondContact O-CB 3.1Å; L51-L55 VanDerWaalsContact O-CG 3.22Å; L51-L55 WeakPolarHBondContact O-CG 3.45Å; L51-L55 PolarHBondContact O-N 3.43Å; M53-L55 PolarHBondContact O-N 3.02Å; L55-S58 WeakPolarHBondContact CA-OG 3.3Å; L55-S58 PolarHBondContact O-N 3.46Å; L55-S58 PolarHBondContact O-OG 2.93Å; L55-M59 WeakPolarHBondContact O-CB 3.02Å; L55-M59 VanDerWaalsContact O-CG 3.31Å; L55-M59 WeakPolarHBondContact O-CG 3.4Å; L55-M59 PolarHBondContact O-N 2.83Å; L55-V90 HydrophobicContact CD2-CG2 4.47Å
56	C	80.2	Confident	82.7	Confident	27 Å²	27	16.7 Å²	16.7	18%	0.182	9%	0.092	C	C	.	.	H	α-helix	trans	-59.5	-50.7	174	-171.3	0	0	0	0	111.5	L52 M53 S58 M59 L60 L283	L52-C56 WeakPolarHBondContact O-CB 3.41Å; L52-C56 PolarHBondContact O-N 3.45Å; M53-C56 PolarHBondContact O-N 2.89Å; C56-S58 PolarHBondContact O-N 3.18Å; C56-M59 PolarHBondContact O-N 3.24Å; C56-L60 VanDerWaalsContact O-CG 3.3Å; C56-L60 WeakPolarHBondContact O-CG 3.44Å; C56-L60 PolarHBondContact O-N 3Å; C56-L283 HydrophobicContact CB-CD2 3.72Å
57	C	86.8	Confident	82.8	Confident	0 Å²	0	17 Å²	17	0%	0	9%	0.092	C	C	.	.	H	α-helix	trans	-62.3	-41.2	178.2	-72	0	0	0	0	112.7	M53 L54 L60 S61 S196 C286	M53-C57 WeakPolarHBondContact O-CB 3.32Å; M53-C57 PolarHBondContact O-N 3.38Å; M53-C57 PolarHBondContact O-SG 3.16Å; M53-C57 VanDerWaalsContact O-SG 3.33Å; L54-C57 PolarHBondContact O-N 3.39Å; C57-L60 PolarHBondContact O-N 3.4Å; C57-S61 VanDerWaalsContact O-CB 3.29Å; C57-S61 WeakPolarHBondContact O-CB 3.37Å; C57-S61 PolarHBondContact O-N 2.91Å; C57-S61 PolarHBondContact O-OG 3.37Å; C57-S196 WeakPolarHBondContact CB-OG 3.21Å; C57-C286 HydrophobicContact CB-CB 4.38Å
58	S	86.2	Confident	83	Confident	2 Å²	2	19.3 Å²	19.3	1%	0.014	10%	0.101	C	C	.	.	H	α-helix	trans	-65.2	-40	179	69.5	0	0	0	0	111.8	L8 L54 L55 C56 S61 L62	L8-S58 VanDerWaalsContact CD2-OG 3.26Å; L8-S58 WeakPolarHBondContact CD2-OG 3.41Å; L54-S58 VanDerWaalsContact O-CB 3.25Å; L54-S58 WeakPolarHBondContact O-CB 3.36Å; L54-S58 PolarHBondContact O-N 2.94Å; L54-S58 PolarHBondContact O-OG 2.95Å; L55-S58 WeakPolarHBondContact CA-OG 3.3Å; L55-S58 PolarHBondContact O-N 3.46Å; L55-S58 PolarHBondContact O-OG 2.93Å; C56-S58 PolarHBondContact O-N 3.18Å; S58-S61 WeakPolarHBondContact CA-OG 3.37Å; S58-S61 PolarHBondContact O-OG 3.5Å; S58-L62 VanDerWaalsContact O-CB 3.26Å; S58-L62 WeakPolarHBondContact O-CB 3.43Å; S58-L62 WeakPolarHBondContact O-CD1 3.34Å; S58-L62 WeakPolarHBondContact O-CG 3.31Å; S58-L62 PolarHBondContact O-N 3.48Å
59	M	80.2	Confident	83.2	Confident	49 Å²	49	20.2 Å²	20.2	24%	0.241	11%	0.105	C	C	.	.	H	α-helix	trans	-64.2	-46.6	175.5	-75.5	-62.1	-90.9	0	0	112.2	V5 L8 L55 C56 C63	V5-M59 HydrophobicContact CB-CE 4.5Å; V5-M59 HydrophobicContact CG1-CE 4.09Å; L8-M59 HydrophobicContact CB-CE 4.07Å; L8-M59 HydrophobicContact CB-CG 3.98Å; L8-M59 HydrophobicContact CB-SD 3.13Å; L8-M59 WeakPolarHBondContact CB-SD 3.48Å; L8-M59 HydrophobicContact CD1-CG 4.3Å; L8-M59 HydrophobicContact CD1-SD 3.34Å; L8-M59 WeakPolarHBondContact CD1-SD 3.25Å; L8-M59 HydrophobicContact CD2-CG 4.48Å; L8-M59 HydrophobicContact CD2-SD 4.35Å; L8-M59 HydrophobicContact CG-CG 4.48Å; L8-M59 HydrophobicContact CG-SD 3.74Å; L55-M59 WeakPolarHBondContact O-CB 3.02Å; L55-M59 VanDerWaalsContact O-CG 3.31Å; L55-M59 WeakPolarHBondContact O-CG 3.4Å; L55-M59 PolarHBondContact O-N 2.83Å; C56-M59 PolarHBondContact O-N 3.24Å; M59-C63 WeakPolarHBondContact O-CB 3.2Å; M59-C63 PolarHBondContact O-N 2.85Å; M59-C63 VanDerWaalsContact O-N 3.1Å; M59-C63 PolarHBondContact O-SG 3.48Å
60	L	82.7	Confident	82.8	Confident	27 Å²	27	25.4 Å²	25.4	14%	0.141	13%	0.131	C	C	.	.	H	α-helix	trans	-63	-48.1	179	-68.3	165.8	0	0	0	111.6	C56 C57 C63 Y64 L287 I290 L401	C56-L60 VanDerWaalsContact O-CG 3.3Å; C56-L60 WeakPolarHBondContact O-CG 3.44Å; C56-L60 PolarHBondContact O-N 3Å; C57-L60 PolarHBondContact O-N 3.4Å; L60-C63 PolarHBondContact O-N 3.47Å; L60-Y64 VanDerWaalsContact O-CB 3.26Å; L60-Y64 WeakPolarHBondContact O-CB 3.41Å; L60-Y64 PolarHBondContact O-N 2.75Å; L60-L287 HydrophobicContact CD1-CD2 4.08Å; L60-I290 HydrophobicContact CB-CD1 4.04Å; L60-L401 HydrophobicContact CD1-CD1 3.62Å; L60-L401 HydrophobicContact CD2-CD1 3.89Å; L60-L401 HydrophobicContact CG-CD1 4.35Å
61	S	87.1	Confident	81.8	Confident	0 Å²	0	32.8 Å²	32.8	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-69.9	-34.3	-177.5	57.8	0	0	0	0	113.5	C57 S58 Y64 A65 S191 L192	C57-S61 VanDerWaalsContact O-CB 3.29Å; C57-S61 WeakPolarHBondContact O-CB 3.37Å; C57-S61 PolarHBondContact O-N 2.91Å; C57-S61 PolarHBondContact O-OG 3.37Å; S58-S61 WeakPolarHBondContact CA-OG 3.37Å; S58-S61 PolarHBondContact O-OG 3.5Å; S61-Y64 PolarHBondContact O-N 3.23Å; S61-A65 PolarHBondContact O-N 2.84Å; S61-S191 VanDerWaalsContact CB-OG 3.28Å; S61-S191 WeakPolarHBondContact CB-OG 3.27Å; S61-L192 WeakPolarHBondContact OG-CD1 3.23Å
62	L	84.9	Confident	81	Confident	17 Å²	17	40.5 Å²	40.5	9%	0.089	20%	0.196	C	C	.	.	H	α-helix	trans	-69.4	-43.2	174.1	-74.6	169	0	0	0	111.9	L8 S58 Y64 A65 F66 A79 M82 F83	L8-L62 HydrophobicContact CD1-CD1 3.29Å; S58-L62 VanDerWaalsContact O-CB 3.26Å; S58-L62 WeakPolarHBondContact O-CB 3.43Å; S58-L62 WeakPolarHBondContact O-CD1 3.34Å; S58-L62 WeakPolarHBondContact O-CG 3.31Å; S58-L62 PolarHBondContact O-N 3.48Å; L62-Y64 VanDerWaalsContact C-N 3.26Å; L62-Y64 PolarHBondContact O-N 3.31Å; L62-A65 WeakPolarHBondContact O-CB 3.38Å; L62-A65 PolarHBondContact O-N 2.94Å; L62-F66 WeakPolarHBondContact O-CD2 3.34Å; L62-A79 HydrophobicContact CD2-CB 4.18Å; L62-A79 WeakPolarHBondContact CD2-O 3.24Å; L62-M82 HydrophobicContact CD2-CB 3.77Å; L62-F83 HydrophobicContact CD1-CD2 4.46Å
63	C	80.9	Confident	80.7	Confident	49 Å²	49	42 Å²	42	33%	0.331	21%	0.21	S	C	.	.	H	α-helix	trans	-60.9	-41	172.9	-69.9	0	0	0	0	110.9	M59 L60 A65 F66 H67 F394	M59-C63 WeakPolarHBondContact O-CB 3.2Å; M59-C63 PolarHBondContact O-N 2.85Å; M59-C63 VanDerWaalsContact O-N 3.1Å; M59-C63 PolarHBondContact O-SG 3.48Å; L60-C63 PolarHBondContact O-N 3.47Å; C63-A65 PolarHBondContact O-N 2.87Å; C63-F66 PolarHBondContact O-N 2.67Å; C63-H67 PolarHBondContact O-N 3.02Å; C63-F394 HydrophobicContact CB-CE1 3.6Å; C63-F394 HydrophobicContact CB-CZ 3.88Å; C63-F394 VanDerWaalsContact O-CZ 3.29Å; C63-F394 WeakPolarHBondContact O-CZ 3.14Å
64	Y	85	Confident	80.4	Confident	0 Å²	0	49.4 Å²	49.4	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-64.4	-36.4	176.4	-179.6	-114.6	0	0	0	113.2	L60 S61 L62 F66 H67 Y68 T187 P188 I290 G293 D294	L60-Y64 VanDerWaalsContact O-CB 3.26Å; L60-Y64 WeakPolarHBondContact O-CB 3.41Å; L60-Y64 PolarHBondContact O-N 2.75Å; S61-Y64 PolarHBondContact O-N 3.23Å; L62-Y64 VanDerWaalsContact C-N 3.26Å; L62-Y64 PolarHBondContact O-N 3.31Å; Y64-F66 VanDerWaalsContact C-N 3.26Å; Y64-F66 PolarHBondContact O-N 3.38Å; Y64-H67 WeakPolarHBondContact O-CB 3.24Å; Y64-H67 PolarHBondContact O-N 3.45Å; Y64-Y68 HydrophobicContact CE1-CD2 4.34Å; Y64-Y68 HydrophobicContact CE1-CG 4.32Å; Y64-Y68 AromaticContact CZ-CD2 3.89Å; Y64-Y68 WeakPolarHBondContact O-CB 3.39Å; Y64-Y68 PolarHBondContact O-N 3.02Å; Y64-Y68 VanDerWaalsContact OH-CD2 3.25Å; Y64-Y68 WeakPolarHBondContact OH-CD2 3.33Å; Y64-T187 PolarHBondContact OH-OG1 3.3Å; Y64-P188 HydrophobicContact CD1-CB 3.76Å; Y64-P188 HydrophobicContact CE1-CB 4.19Å; Y64-I290 HydrophobicContact CD1-CG1 3.94Å; Y64-I290 HydrophobicContact CD2-CB 4.33Å; Y64-I290 HydrophobicContact CD2-CG1 4.24Å; Y64-I290 HydrophobicContact CD2-CG2 3.62Å; Y64-I290 HydrophobicContact CE1-CG1 4.48Å; Y64-I290 HydrophobicContact CE2-CB 4.46Å; Y64-I290 HydrophobicContact CE2-CG2 3.83Å; Y64-I290 HydrophobicContact CG-CB 4.39Å; Y64-I290 HydrophobicContact CG-CG1 3.82Å; Y64-I290 HydrophobicContact CG-CG2 4.1Å; Y64-I290 PolarHBondContact OH-O 3.26Å; Y64-G293 WeakPolarHBondContact OH-CA 3.35Å; Y64-D294 VanDerWaalsContact CE2-OD1 3.31Å; Y64-D294 WeakPolarHBondContact CE2-OD1 2.98Å; Y64-D294 PolarHBondContact OH-N 3.42Å
65	A	86.6	Confident	80.1	Confident	0 Å²	0	49.3 Å²	49.3	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-57.9	-37.7	178.4	0	0	0	0	0	112.8	S61 L62 C63 L69 M82 P188	S61-A65 PolarHBondContact O-N 2.84Å; L62-A65 WeakPolarHBondContact O-CB 3.38Å; L62-A65 PolarHBondContact O-N 2.94Å; C63-A65 PolarHBondContact O-N 2.87Å; A65-L69 PolarHBondContact O-N 3.02Å; A65-M82 HydrophobicContact CB-SD 4.03Å; A65-P188 HydrophobicContact CB-CB 3.89Å; A65-P188 HydrophobicContact CB-CG 4.31Å
66	F	82.2	Confident	80.2	Confident	60 Å²	60	55.3 Å²	55.3	26%	0.263	27%	0.265	S	S	.	.	H	α-helix	trans	-73.6	-24.8	175.8	-66.3	-69.3	0	0	0	113.9	L62 C63 Y64 L69 K76 A79	L62-F66 WeakPolarHBondContact O-CD2 3.34Å; C63-F66 PolarHBondContact O-N 2.67Å; Y64-F66 VanDerWaalsContact C-N 3.26Å; Y64-F66 PolarHBondContact O-N 3.38Å; F66-L69 CarbonylContact C-O 3.51Å; F66-K76 HydrophobicContact CE1-CG 4.39Å; F66-A79 HydrophobicContact CE1-CB 4.16Å; F66-A79 HydrophobicContact CE2-CB 4.09Å; F66-A79 HydrophobicContact CZ-CB 3.61Å
67	H	81.5	Confident	80.5	Confident	51 Å²	51	59 Å²	59	24%	0.236	28%	0.282	C	S	.	.	H	α-helix	trans	-79.5	-39.8	173.8	179.3	-101.4	0	0	0	111.8	C63 Y64 D294 S390 F394	C63-H67 PolarHBondContact O-N 3.02Å; Y64-H67 WeakPolarHBondContact O-CB 3.24Å; Y64-H67 PolarHBondContact O-N 3.45Å; H67-D294 IonicContact CE1-OD1 3.32Å; H67-D294 PolarHBondContact CE1-OD1 2.94Å; H67-D294 IonicContact ND1-OD1 3.32Å; H67-D294 PolarHBondContact ND1-OD1 3.26Å; H67-S390 PolarHBondContact NE2-O 3.34Å; H67-F394 HydrophobicContact CB-CD2 4.02Å; H67-F394 HydrophobicContact CB-CE2 3.44Å; H67-F394 VanDerWaalsContact CB-CE2 3.44Å; H67-F394 HydrophobicContact CB-CZ 4.11Å; H67-F394 AromaticContact CD2-CD2 3.96Å; H67-F394 AromaticContact CD2-CE2 3.93Å; H67-F394 AromaticContact CG-CD2 3.82Å; H67-F394 AromaticContact CG-CE2 3.71Å
68	Y	84.5	Confident	80.6	Confident	49 Å²	49	59 Å²	59	19%	0.192	28%	0.282	C	S	.	.	H	α-helix	trans	-74.7	-40.4	-176.3	-174.5	-101.7	0	0	0	112.4	Y64 P186 T187 P188	Y64-Y68 HydrophobicContact CE1-CD2 4.34Å; Y64-Y68 HydrophobicContact CE1-CG 4.32Å; Y64-Y68 AromaticContact CZ-CD2 3.89Å; Y64-Y68 WeakPolarHBondContact O-CB 3.39Å; Y64-Y68 PolarHBondContact O-N 3.02Å; Y64-Y68 VanDerWaalsContact OH-CD2 3.25Å; Y64-Y68 WeakPolarHBondContact OH-CD2 3.33Å; Y68-P186 HydrophobicContact CE1-CB 4.42Å; Y68-T187 WeakPolarHBondContact CD2-OG1 3.26Å; Y68-T187 HydrophobicContact CE2-CG2 4.49Å; Y68-T187 WeakPolarHBondContact CE2-OG1 3.23Å; Y68-T187 VanDerWaalsContact CZ-OG1 3.24Å; Y68-P188 HydrophobicContact CD1-CG 4.09Å
69	L	79.8	Confident	80.6	Confident	33 Å²	33	59.4 Å²	59.4	17%	0.173	28%	0.284	C	S	.	.	S	Bend	trans	-109.9	107.7	170.4	-63.4	172.2	0	0	0	106.4	A65 F66 L78 Y117	A65-L69 PolarHBondContact O-N 3.02Å; F66-L69 CarbonylContact C-O 3.51Å; L69-L78 HydrophobicContact CD1-CB 4.3Å; L69-L78 HydrophobicContact CD1-CD2 3.54Å; L69-Y117 HydrophobicContact CD1-CE1 4.04Å
70	D	70.4	Confident	80.9	Confident	115 Å²	115	61.5 Å²	61.5	62%	0.615	30%	0.3	S	S	*	.			trans	-38.3	149.2	172.1	-73.5	-29.1	0	0	0	111.1	Y72	D70-Y72 HydrophobicContact CB-CD2 3.58Å; D70-Y72 HydrophobicContact CB-CE2 3.75Å; D70-Y72 PolarHBondContact O-N 3.03Å
71	E	62.8	Low	81.1	Confident	157 Å²	157	61.8 Å²	61.8	73%	0.734	30%	0.304	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.8	3.3	-165.5	-61.3	-171.3	162.8	0	0	117.6
72	Y	65.3	Low	81.2	Confident	167 Å²	167	61.9 Å²	61.9	66%	0.655	31%	0.305	S	S	*	.	T	Hydrogen-bonded Turn	trans	-53.8	160.9	170.9	-60.9	-73.4	0	0	0	112.9	D70 Y74 G75	D70-Y72 HydrophobicContact CB-CD2 3.58Å; D70-Y72 HydrophobicContact CB-CE2 3.75Å; D70-Y72 PolarHBondContact O-N 3.03Å; Y72-Y74 PolarHBondContact O-N 3.21Å; Y72-G75 PolarHBondContact O-N 2.98Å
73	S	73.8	Confident	81.3	Confident	74 Å²	74	63.1 Å²	63.1	52%	0.517	31%	0.309	S	S	.	.	H	α-helix	trans	-46.7	-35.1	-176.9	48.8	0	0	0	0	114.4	K76 I77	S73-K76 PolarHBondContact O-N 2.7Å; S73-I77 WeakPolarHBondContact O-CG1 3.25Å; S73-I77 PolarHBondContact O-N 3.35Å
74	Y	79.3	Confident	81.5	Confident	157 Å²	157	65.7 Å²	65.7	62%	0.616	32%	0.318	S	S	*	.	H	α-helix	trans	-57.3	-49.4	177.6	-63.2	-66.5	0	0	0	112.9	Y72 K76 I77 L78 Y117	Y72-Y74 PolarHBondContact O-N 3.21Å; Y74-K76 VanDerWaalsContact C-N 3.26Å; Y74-K76 PolarHBondContact O-N 3.36Å; Y74-I77 PolarHBondContact O-N 3.21Å; Y74-L78 PolarHBondContact O-N 3.33Å; Y74-Y117 VanDerWaalsContact C-OH 3.24Å; Y74-Y117 WeakPolarHBondContact CA-OH 3.35Å; Y74-Y117 WeakPolarHBondContact CB-OH 3.3Å; Y74-Y117 PolarHBondContact O-OH 3.38Å
75	G	80.6	Confident	81.7	Confident	0 Å²	0	65.7 Å²	65.7	0%	0	32%	0.318	C	S	.	.	H	α-helix	trans	-61.2	-35.1	179.6	0	0	0	0	0	112.8	Y72 L78 A79	Y72-G75 PolarHBondContact O-N 2.98Å; G75-L78 PolarHBondContact O-N 2.95Å; G75-A79 WeakPolarHBondContact O-CB 3.41Å; G75-A79 PolarHBondContact O-N 3.15Å
76	K	83.1	Confident	81.8	Confident	128 Å²	128	65.8 Å²	65.8	56%	0.557	32%	0.319	S	S	*	.	H	α-helix	trans	-66.4	-42.3	177	-64.1	179.1	-174.9	173.6	0	112.2	F66 S73 Y74 L78 A79 V80	F66-K76 HydrophobicContact CE1-CG 4.39Å; S73-K76 PolarHBondContact O-N 2.7Å; Y74-K76 VanDerWaalsContact C-N 3.26Å; Y74-K76 PolarHBondContact O-N 3.36Å; K76-L78 VanDerWaalsContact C-N 3.33Å; K76-A79 PolarHBondContact O-N 3.45Å; K76-V80 VanDerWaalsContact O-CG2 3.32Å; K76-V80 WeakPolarHBondContact O-CG2 3.37Å; K76-V80 PolarHBondContact O-N 3.2Å
77	I	86.1	Confident	81.8	Confident	105 Å²	105	64.8 Å²	64.8	54%	0.538	32%	0.318	S	S	.	.	H	α-helix	trans	-62.7	-44.2	178.4	-64.9	166.2	0	0	0	110.1	S73 Y74 V80 S81 Y117	S73-I77 WeakPolarHBondContact O-CG1 3.25Å; S73-I77 PolarHBondContact O-N 3.35Å; Y74-I77 PolarHBondContact O-N 3.21Å; I77-V80 PolarHBondContact O-N 3.1Å; I77-S81 PolarHBondContact O-N 2.72Å; I77-S81 VanDerWaalsContact O-N 3.07Å; I77-S81 PolarHBondContact O-OG 2.71Å; I77-Y117 HydrophobicContact CG2-CE2 4.47Å
78	L	89	Confident	82.1	Confident	0 Å²	0	63.7 Å²	63.7	0%	0	31%	0.314	C	S	.	.	H	α-helix	trans	-63.1	-43.7	176.2	-170.9	69.6	0	0	0	112.1	L69 Y74 G75 K76 V80 S81 M82 L114 Y117 P186 P188 V189	L69-L78 HydrophobicContact CD1-CB 4.3Å; L69-L78 HydrophobicContact CD1-CD2 3.54Å; Y74-L78 PolarHBondContact O-N 3.33Å; G75-L78 PolarHBondContact O-N 2.95Å; K76-L78 VanDerWaalsContact C-N 3.33Å; L78-V80 VanDerWaalsContact C-N 3.32Å; L78-V80 PolarHBondContact O-N 2.58Å; L78-S81 WeakPolarHBondContact CA-OG 3.24Å; L78-S81 PolarHBondContact O-N 2.96Å; L78-S81 PolarHBondContact O-OG 3.43Å; L78-M82 HydrophobicContact CD2-SD 4.35Å; L78-M82 HydrophobicContact CG-CG 4.43Å; L78-M82 HydrophobicContact CG-SD 4.04Å; L78-M82 WeakPolarHBondContact O-CB 3.13Å; L78-M82 VanDerWaalsContact O-CG 3.26Å; L78-M82 WeakPolarHBondContact O-CG 3.25Å; L78-M82 PolarHBondContact O-N 3.04Å; L78-L114 HydrophobicContact CD1-CD2 4.41Å; L78-Y117 HydrophobicContact CB-CD2 4.45Å; L78-Y117 HydrophobicContact CB-CE2 3.9Å; L78-Y117 HydrophobicContact CD1-CD1 4.16Å; L78-Y117 HydrophobicContact CD1-CD2 3.72Å; L78-Y117 HydrophobicContact CD1-CE1 4.43Å; L78-Y117 HydrophobicContact CD1-CE2 4.02Å; L78-Y117 HydrophobicContact CD1-CG 3.79Å; L78-P186 HydrophobicContact CD1-CG 4.13Å; L78-P186 HydrophobicContact CD2-CB 4.38Å; L78-P186 HydrophobicContact CD2-CG 4.18Å; L78-P188 HydrophobicContact CD2-CG 3.75Å; L78-V189 HydrophobicContact CD1-CG2 3.65Å; L78-V189 HydrophobicContact CD2-CG2 4.47Å; L78-V189 HydrophobicContact CG-CG2 4.34Å
79	A	86.4	Confident	82.3	Confident	9 Å²	9	61.4 Å²	61.4	7%	0.074	31%	0.305	C	S	.	.	H	α-helix	trans	-63.1	-38.9	178.8	0	0	0	0	0	112	L62 F66 G75 K76 F83	L62-A79 HydrophobicContact CD2-CB 4.18Å; L62-A79 WeakPolarHBondContact CD2-O 3.24Å; F66-A79 HydrophobicContact CE1-CB 4.16Å; F66-A79 HydrophobicContact CE2-CB 4.09Å; F66-A79 HydrophobicContact CZ-CB 3.61Å; G75-A79 WeakPolarHBondContact O-CB 3.41Å; G75-A79 PolarHBondContact O-N 3.15Å; K76-A79 PolarHBondContact O-N 3.45Å; A79-F83 WeakPolarHBondContact O-CB 3.22Å; A79-F83 PolarHBondContact O-N 3.14Å
80	V	86.3	Confident	82.5	Confident	93 Å²	93	60.7 Å²	60.7	56%	0.564	30%	0.303	S	S	*	.	H	α-helix	trans	-64.9	-45.5	175.9	171.8	0	0	0	0	110.9	K76 I77 L78 M82 F83 M84	K76-V80 VanDerWaalsContact O-CG2 3.32Å; K76-V80 WeakPolarHBondContact O-CG2 3.37Å; K76-V80 PolarHBondContact O-N 3.2Å; I77-V80 PolarHBondContact O-N 3.1Å; L78-V80 VanDerWaalsContact C-N 3.32Å; L78-V80 PolarHBondContact O-N 2.58Å; V80-M82 PolarHBondContact O-N 3.27Å; V80-F83 PolarHBondContact O-N 2.95Å; V80-M84 WeakPolarHBondContact O-CG 3.33Å; V80-M84 PolarHBondContact O-N 3.3Å
81	S	87.5	Confident	83.1	Confident	34 Å²	34	58.4 Å²	58.4	24%	0.238	29%	0.292	C	S	.	.	H	α-helix	trans	-66.7	-36.9	178.3	58	0	0	0	0	112.7	I77 L78 M84 F85 L114	I77-S81 PolarHBondContact O-N 2.72Å; I77-S81 VanDerWaalsContact O-N 3.07Å; I77-S81 PolarHBondContact O-OG 2.71Å; L78-S81 WeakPolarHBondContact CA-OG 3.24Å; L78-S81 PolarHBondContact O-N 2.96Å; L78-S81 PolarHBondContact O-OG 3.43Å; S81-M84 PolarHBondContact O-N 2.76Å; S81-F85 PolarHBondContact O-N 3.42Å; S81-L114 WeakPolarHBondContact OG-CD2 3.29Å
82	M	89.4	Confident	84.2	Confident	1 Å²	1	50.9 Å²	50.9	1%	0.005	26%	0.257	C	S	.	.	H	α-helix	trans	-64	-39.1	172.6	-73.5	177.8	67.4	0	0	112.4	L62 A65 L78 V80 F85 S86 L114 P188 V189 L192	L62-M82 HydrophobicContact CD2-CB 3.77Å; A65-M82 HydrophobicContact CB-SD 4.03Å; L78-M82 HydrophobicContact CD2-SD 4.35Å; L78-M82 HydrophobicContact CG-CG 4.43Å; L78-M82 HydrophobicContact CG-SD 4.04Å; L78-M82 WeakPolarHBondContact O-CB 3.13Å; L78-M82 VanDerWaalsContact O-CG 3.26Å; L78-M82 WeakPolarHBondContact O-CG 3.25Å; L78-M82 PolarHBondContact O-N 3.04Å; V80-M82 PolarHBondContact O-N 3.27Å; M82-F85 PolarHBondContact O-N 3.24Å; M82-S86 PolarHBondContact O-N 3.35Å; M82-L114 HydrophobicContact CG-CD2 4.11Å; M82-P188 HydrophobicContact CE-CB 4.08Å; M82-P188 WeakPolarHBondContact CE-O 3.46Å; M82-P188 HydrophobicContact SD-CB 4.04Å; M82-V189 HydrophobicContact CG-CG2 4.16Å; M82-V189 HydrophobicContact SD-CG2 4.19Å; M82-L192 HydrophobicContact CB-CD1 4.27Å; M82-L192 HydrophobicContact CE-CB 4.08Å; M82-L192 HydrophobicContact CE-CD1 3.72Å
83	F	86.9	Confident	85.2	Confident	43 Å²	43	43.1 Å²	43.1	19%	0.189	23%	0.227	C	C	.	.	H	α-helix	trans	-66.2	-43.9	175	178.9	-96.8	0	0	0	111.7	L7 L8 L62 A79 V80 F85 S86 T87	L7-F83 HydrophobicContact CD1-CZ 4.15Å; L7-F83 HydrophobicContact CD2-CE2 4.44Å; L7-F83 HydrophobicContact CD2-CZ 3.98Å; L8-F83 HydrophobicContact CD1-CD2 4.35Å; L8-F83 HydrophobicContact CG-CE2 4.32Å; L62-F83 HydrophobicContact CD1-CD2 4.46Å; A79-F83 WeakPolarHBondContact O-CB 3.22Å; A79-F83 PolarHBondContact O-N 3.14Å; V80-F83 PolarHBondContact O-N 2.95Å; F83-F85 PolarHBondContact O-N 3.39Å; F83-S86 PolarHBondContact O-N 3.01Å; F83-S86 PolarHBondContact O-OG 3.34Å; F83-T87 HydrophobicContact CD1-CG2 4.13Å; F83-T87 HydrophobicContact CE1-CG2 3.67Å; F83-T87 HydrophobicContact CE2-CG2 4.22Å; F83-T87 HydrophobicContact CZ-CG2 3.71Å; F83-T87 WeakPolarHBondContact O-CG2 3.46Å; F83-T87 PolarHBondContact O-N 3.47Å; F83-T87 PolarHBondContact O-OG1 2.9Å
84	M	85.7	Confident	85.3	Confident	103 Å²	103	40.5 Å²	40.5	51%	0.507	21%	0.207	S	C	.	.	H	α-helix	trans	-56.5	-43.5	173.8	-68.7	-58.2	-65.9	0	0	111	V80 S81 T87 V88	V80-M84 WeakPolarHBondContact O-CG 3.33Å; V80-M84 PolarHBondContact O-N 3.3Å; S81-M84 PolarHBondContact O-N 2.76Å; M84-T87 PolarHBondContact O-N 3.49Å; M84-T87 PolarHBondContact O-OG1 3.39Å; M84-V88 WeakPolarHBondContact O-CG2 3.17Å; M84-V88 PolarHBondContact O-N 3.42Å
85	F	88.9	Confident	85.2	Confident	0 Å²	0	33.2 Å²	33.2	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-63.8	-41	177.3	-179.7	-102.6	0	0	0	113.7	S81 M82 F83 V88 M89 L107 V110 L114 L192 V193 T197	S81-F85 PolarHBondContact O-N 3.42Å; M82-F85 PolarHBondContact O-N 3.24Å; F83-F85 PolarHBondContact O-N 3.39Å; F85-V88 PolarHBondContact O-N 3.5Å; F85-M89 PolarHBondContact O-N 3.45Å; F85-L107 HydrophobicContact CE2-CD1 4.47Å; F85-L107 HydrophobicContact CE2-CD2 4.14Å; F85-L107 HydrophobicContact CE2-CG 3.79Å; F85-L107 HydrophobicContact CZ-CD2 4.36Å; F85-L107 HydrophobicContact CZ-CG 4.24Å; F85-V110 HydrophobicContact CB-CG1 3.61Å; F85-V110 HydrophobicContact CD2-CB 3.95Å; F85-V110 HydrophobicContact CD2-CG1 3.74Å; F85-V110 HydrophobicContact CG-CG1 4.14Å; F85-L114 HydrophobicContact CB-CD1 3.76Å; F85-L114 HydrophobicContact CD1-CD1 4.26Å; F85-L114 HydrophobicContact CD2-CD1 4.13Å; F85-L114 HydrophobicContact CG-CD1 3.8Å; F85-L192 HydrophobicContact CD1-CD2 3.32Å; F85-L192 HydrophobicContact CE1-CD2 3.3Å; F85-V193 HydrophobicContact CD1-CG2 4.15Å; F85-V193 HydrophobicContact CE1-CB 4.21Å; F85-V193 HydrophobicContact CE1-CG1 4.45Å; F85-V193 HydrophobicContact CE1-CG2 3.6Å; F85-V193 HydrophobicContact CZ-CB 4.25Å; F85-V193 HydrophobicContact CZ-CG1 3.99Å; F85-V193 HydrophobicContact CZ-CG2 3.84Å; F85-T197 HydrophobicContact CE1-CG2 3.81Å; F85-T197 WeakPolarHBondContact CE1-OG1 3.37Å; F85-T197 HydrophobicContact CZ-CG2 4.49Å; F85-T197 WeakPolarHBondContact CZ-OG1 3.13Å
86	S	87.2	Confident	84.9	Confident	3 Å²	3	38.8 Å²	38.8	2%	0.021	20%	0.201	C	C	.	.	H	α-helix	trans	-66.3	-38.3	175.9	69.3	0	0	0	0	111.9	M82 F83 V88 M89 V90	M82-S86 PolarHBondContact O-N 3.35Å; F83-S86 PolarHBondContact O-N 3.01Å; F83-S86 PolarHBondContact O-OG 3.34Å; S86-V88 PolarHBondContact O-N 2.92Å; S86-M89 PolarHBondContact O-N 3.2Å; S86-V90 WeakPolarHBondContact O-CG2 3.4Å; S86-V90 PolarHBondContact O-N 3Å
87	T	83	Confident	84.6	Confident	39 Å²	39	36 Å²	36	24%	0.239	19%	0.19	C	C	.	.	H	α-helix	trans	-63.2	-40.2	177.8	60.6	0	0	0	0	112.9	F83 M84 M89 V90 V91	F83-T87 HydrophobicContact CD1-CG2 4.13Å; F83-T87 HydrophobicContact CE1-CG2 3.67Å; F83-T87 HydrophobicContact CE2-CG2 4.22Å; F83-T87 HydrophobicContact CZ-CG2 3.71Å; F83-T87 WeakPolarHBondContact O-CG2 3.46Å; F83-T87 PolarHBondContact O-N 3.47Å; F83-T87 PolarHBondContact O-OG1 2.9Å; M84-T87 PolarHBondContact O-N 3.49Å; M84-T87 PolarHBondContact O-OG1 3.39Å; T87-M89 VanDerWaalsContact C-N 3.3Å; T87-M89 PolarHBondContact O-N 2.72Å; T87-V90 PolarHBondContact O-N 2.79Å; T87-V91 WeakPolarHBondContact O-CG2 3.5Å; T87-V91 PolarHBondContact O-N 3.49Å
88	V	87.9	Confident	84.3	Confident	28 Å²	28	31.3 Å²	31.3	17%	0.17	17%	0.166	C	C	.	.	H	α-helix	trans	-60.4	-42.8	175.2	173.8	0	0	0	0	110.8	M84 F85 S86 V91 L92 L107	M84-V88 WeakPolarHBondContact O-CG2 3.17Å; M84-V88 PolarHBondContact O-N 3.42Å; F85-V88 PolarHBondContact O-N 3.5Å; S86-V88 PolarHBondContact O-N 2.92Å; V88-V91 PolarHBondContact O-N 3.12Å; V88-L92 WeakPolarHBondContact O-CB 3.46Å; V88-L92 PolarHBondContact O-N 3.11Å; V88-L107 HydrophobicContact CG1-CB 4.34Å
89	M	88.7	Confident	83.9	Confident	0 Å²	0	32.6 Å²	32.6	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-68.9	-37	177.5	-175	66.7	-175	0	0	112.4	L54 F85 S86 T87 L92 V93 L107 T197 A201	L54-M89 HydrophobicContact CD1-CB 3.66Å; L54-M89 HydrophobicContact CD1-CG 3.08Å; F85-M89 PolarHBondContact O-N 3.45Å; S86-M89 PolarHBondContact O-N 3.2Å; T87-M89 VanDerWaalsContact C-N 3.3Å; T87-M89 PolarHBondContact O-N 2.72Å; M89-L92 HydrophobicContact CE-CD2 4.23Å; M89-L92 PolarHBondContact O-N 2.93Å; M89-L92 HydrophobicContact SD-CD2 3.81Å; M89-V93 HydrophobicContact CE-CG2 3.7Å; M89-V93 WeakPolarHBondContact O-CG2 3.22Å; M89-V93 PolarHBondContact O-N 3.36Å; M89-V93 HydrophobicContact SD-CG2 4.41Å; M89-L107 HydrophobicContact CB-CD1 4.04Å; M89-L107 HydrophobicContact CG-CD1 4.27Å; M89-L107 HydrophobicContact SD-CD1 3.5Å; M89-L107 VanDerWaalsContact SD-CD1 3.5Å; M89-T197 HydrophobicContact CB-CG2 4.36Å; M89-T197 HydrophobicContact CG-CG2 4.08Å; M89-A201 HydrophobicContact CE-CB 4.03Å; M89-A201 HydrophobicContact SD-CB 4Å
90	V	84.3	Confident	83.7	Confident	19 Å²	19	32.4 Å²	32.4	12%	0.115	17%	0.172	C	C	.	.	H	α-helix	trans	-59.8	-48.2	172.5	172.2	0	0	0	0	110.6	L51 L54 L55 S86 T87 L92 V93 L94	L51-V90 HydrophobicContact CD2-CG1 4.08Å; L51-V90 HydrophobicContact CD2-CG2 4.46Å; L54-V90 HydrophobicContact CD2-CG2 3.31Å; L55-V90 HydrophobicContact CD2-CG2 4.47Å; S86-V90 WeakPolarHBondContact O-CG2 3.4Å; S86-V90 PolarHBondContact O-N 3Å; T87-V90 PolarHBondContact O-N 2.79Å; V90-L92 VanDerWaalsContact C-N 3.28Å; V90-L92 PolarHBondContact O-N 3.18Å; V90-V93 PolarHBondContact O-N 3.03Å; V90-L94 HydrophobicContact CG1-CD1 3.69Å; V90-L94 HydrophobicContact CG1-CG 4.29Å; V90-L94 WeakPolarHBondContact O-CB 3.43Å; V90-L94 VanDerWaalsContact O-CG 3.26Å; V90-L94 WeakPolarHBondContact O-CG 3.35Å; V90-L94 PolarHBondContact O-N 3.2Å
91	V	82.4	Confident	83.5	Confident	66 Å²	66	28 Å²	28	40%	0.4	15%	0.145	S	C	.	.	H	α-helix	trans	-59.3	-42.8	178.8	171.7	0	0	0	0	110.7	T87 V88 L94 S95	T87-V91 WeakPolarHBondContact O-CG2 3.5Å; T87-V91 PolarHBondContact O-N 3.49Å; V88-V91 PolarHBondContact O-N 3.12Å; V91-L94 PolarHBondContact O-N 3.46Å; V91-S95 VanDerWaalsContact O-CB 3.3Å; V91-S95 WeakPolarHBondContact O-CB 3.36Å; V91-S95 PolarHBondContact O-N 2.76Å; V91-S95 VanDerWaalsContact O-N 3.14Å; V91-S95 PolarHBondContact O-OG 3.37Å
92	L	86.7	Confident	83.5	Confident	0 Å²	0	28.1 Å²	28.1	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-60.9	-49.6	177.2	176.3	135.9	0	0	0	112.3	V88 M89 V90 L94 S95 M103 L104 W204	V88-L92 WeakPolarHBondContact O-CB 3.46Å; V88-L92 PolarHBondContact O-N 3.11Å; M89-L92 HydrophobicContact CE-CD2 4.23Å; M89-L92 PolarHBondContact O-N 2.93Å; M89-L92 HydrophobicContact SD-CD2 3.81Å; V90-L92 VanDerWaalsContact C-N 3.28Å; V90-L92 PolarHBondContact O-N 3.18Å; L92-L94 VanDerWaalsContact C-N 3.27Å; L92-L94 PolarHBondContact O-N 3.08Å; L92-S95 PolarHBondContact O-N 3.35Å; L92-S95 VanDerWaalsContact O-N 3.16Å; L92-S95 PolarHBondContact O-OG 3.4Å; L92-M103 HydrophobicContact CB-CB 4.22Å; L92-M103 HydrophobicContact CD1-CB 3.99Å; L92-L104 HydrophobicContact CD1-CB 4.37Å; L92-L104 HydrophobicContact CD1-CD2 3.53Å; L92-L104 HydrophobicContact CD1-CG 3.61Å; L92-W204 HydrophobicContact CD1-CZ3 4.34Å; L92-W204 HydrophobicContact CD2-CD2 4.05Å; L92-W204 HydrophobicContact CD2-CE3 3.42Å; L92-W204 VanDerWaalsContact CD2-CE3 3.42Å; L92-W204 HydrophobicContact CD2-CH2 3.86Å; L92-W204 HydrophobicContact CD2-CZ2 4.44Å; L92-W204 HydrophobicContact CD2-CZ3 3.33Å; L92-W204 HydrophobicContact CG-CE3 4.32Å; L92-W204 HydrophobicContact CG-CH2 4Å; L92-W204 HydrophobicContact CG-CZ3 3.71Å; L92-W204 VanDerWaalsContact O-CH2 3.24Å; L92-W204 WeakPolarHBondContact O-CH2 3.47Å; L92-W204 WeakPolarHBondContact O-CZ2 3.23Å
93	V	85	Confident	83.3	Confident	4 Å²	4	30.9 Å²	30.9	2%	0.024	16%	0.157	C	C	.	.	H	α-helix	trans	-65.8	-30.9	-178.6	175.4	0	0	0	0	112.5	M50 L51 M89 V90 S95	M50-V93 HydrophobicContact CB-CG1 3.99Å; L51-V93 HydrophobicContact CD1-CG1 4.41Å; L51-V93 HydrophobicContact CD2-CB 4.29Å; L51-V93 HydrophobicContact CD2-CG1 4.13Å; L51-V93 HydrophobicContact CG-CG1 3.81Å; M89-V93 HydrophobicContact CE-CG2 3.7Å; M89-V93 WeakPolarHBondContact O-CG2 3.22Å; M89-V93 PolarHBondContact O-N 3.36Å; M89-V93 HydrophobicContact SD-CG2 4.41Å; V90-V93 PolarHBondContact O-N 3.03Å; V93-S95 VanDerWaalsContact C-N 3.32Å
94	L	77.8	Confident	83.4	Confident	18 Å²	18	28.8 Å²	28.8	9%	0.094	15%	0.148	C	C	.	.	H	α-helix	trans	-79.6	-15.6	177.5	-69.4	178.9	0	0	0	114.1	L40 H41 F42 L51 V90 V91 L92	L40-L94 WeakPolarHBondContact CA-O 3.42Å; L40-L94 HydrophobicContact CD2-CB 4Å; H41-L94 PolarHBondContact N-O 3.48Å; F42-L94 HydrophobicContact CD1-CD2 3.26Å; F42-L94 HydrophobicContact CE1-CD1 3.63Å; F42-L94 HydrophobicContact CE1-CD2 3.15Å; F42-L94 HydrophobicContact CE1-CG 4Å; F42-L94 HydrophobicContact CG-CD2 4.26Å; F42-L94 HydrophobicContact CZ-CD1 3.98Å; F42-L94 HydrophobicContact CZ-CD2 4.03Å; L51-L94 HydrophobicContact CD1-CD2 3.48Å; L51-L94 VanDerWaalsContact CD1-CD2 3.48Å; L51-L94 HydrophobicContact CD1-CG 4.3Å; L51-L94 HydrophobicContact CD2-CD2 4.36Å; L51-L94 HydrophobicContact CD2-CG 4.31Å; L51-L94 HydrophobicContact CG-CD2 4.49Å; V90-L94 HydrophobicContact CG1-CD1 3.69Å; V90-L94 HydrophobicContact CG1-CG 4.29Å; V90-L94 WeakPolarHBondContact O-CB 3.43Å; V90-L94 VanDerWaalsContact O-CG 3.26Å; V90-L94 WeakPolarHBondContact O-CG 3.35Å; V90-L94 PolarHBondContact O-N 3.2Å; V91-L94 PolarHBondContact O-N 3.46Å; L92-L94 VanDerWaalsContact C-N 3.27Å; L92-L94 PolarHBondContact O-N 3.08Å
95	S	76.6	Confident	83.7	Confident	4 Å²	4	26.1 Å²	26.1	3%	0.028	13%	0.134	C	C	.	.	B	Isolated β-bridge	trans	-89.3	126.7	-176.7	75.7	0	0	0	0	110.4	V91 L92 V93 S100	V91-S95 VanDerWaalsContact O-CB 3.3Å; V91-S95 WeakPolarHBondContact O-CB 3.36Å; V91-S95 PolarHBondContact O-N 2.76Å; V91-S95 VanDerWaalsContact O-N 3.14Å; V91-S95 PolarHBondContact O-OG 3.37Å; L92-S95 PolarHBondContact O-N 3.35Å; L92-S95 VanDerWaalsContact O-N 3.16Å; L92-S95 PolarHBondContact O-OG 3.4Å; V93-S95 VanDerWaalsContact C-N 3.32Å; S95-S100 WeakPolarHBondContact CB-OG 3.5Å; S95-S100 WeakPolarHBondContact OG-CB 3.48Å; S95-S100 PolarHBondContact OG-OG 3.39Å
96	Y	73.1	Confident	83.7	Confident	117 Å²	117	32.3 Å²	32.3	46%	0.459	16%	0.158	S	C	.	.			trans	-101.4	-16	-177	-169.9	-106.5	0	0	0	113.4	H41 Y209	H41-Y96 HydrophobicContact CB-CG 4.43Å; Y96-Y209 PolarHBondContact O-OH 2.78Å
97	E	77.9	Confident	83.8	Confident	71 Å²	71	32.2 Å²	32.2	33%	0.332	16%	0.157	S	C	.	.	S	Bend	trans	-71.9	135.8	-178.3	-70.9	-62.3	159.9	0	0	111	V99 S100 Y209	E97-V99 PolarHBondContact O-N 3.21Å; E97-V99 VanDerWaalsContact O-N 3.14Å; E97-S100 PolarHBondContact O-N 3.42Å; E97-S100 PolarHBondContact O-OG 2.96Å; E97-Y209 PolarHBondContact O-OH 2.87Å
98	V	79	Confident	84.1	Confident	6 Å²	6	30.4 Å²	30.4	4%	0.036	15%	0.147	C	C	.	.	G	3₁₀ helix	trans	-58	-37.1	178.1	-164	0	0	0	0	109.9	S100 T101 L144 L145 Y148 Y209	V98-S100 VanDerWaalsContact C-N 3.29Å; V98-S100 PolarHBondContact O-N 3.46Å; V98-T101 VanDerWaalsContact O-CB 3.26Å; V98-T101 WeakPolarHBondContact O-CB 3.29Å; V98-T101 VanDerWaalsContact O-CG2 3.23Å; V98-T101 WeakPolarHBondContact O-CG2 3.47Å; V98-T101 PolarHBondContact O-N 2.77Å; V98-T101 VanDerWaalsContact O-N 3.1Å; V98-T101 PolarHBondContact O-OG1 3.49Å; V98-L144 HydrophobicContact CG1-CD2 4.45Å; V98-L145 HydrophobicContact CB-CD2 4.13Å; V98-L145 HydrophobicContact CG1-CD2 3.55Å; V98-L145 WeakPolarHBondContact O-CD2 3.24Å; V98-Y148 HydrophobicContact CB-CD1 4.07Å; V98-Y148 HydrophobicContact CB-CE1 4.05Å; V98-Y148 HydrophobicContact CG1-CD1 4.36Å; V98-Y148 HydrophobicContact CG1-CG 4.42Å; V98-Y148 HydrophobicContact CG2-CD1 3.88Å; V98-Y148 HydrophobicContact CG2-CD2 4.31Å; V98-Y148 HydrophobicContact CG2-CE1 3.48Å; V98-Y148 VanDerWaalsContact CG2-CE1 3.48Å; V98-Y148 HydrophobicContact CG2-CE2 3.94Å; V98-Y148 HydrophobicContact CG2-CG 4.28Å; V98-Y209 HydrophobicContact CB-CE1 4.15Å; V98-Y209 HydrophobicContact CG1-CD1 4.31Å; V98-Y209 HydrophobicContact CG1-CE1 4.15Å; V98-Y209 HydrophobicContact CG2-CD1 4.19Å; V98-Y209 HydrophobicContact CG2-CE1 3.8Å
99	V	82.2	Confident	84.2	Confident	26 Å²	26	32 Å²	32	16%	0.158	15%	0.154	C	C	.	.	G	3₁₀ helix	trans	-62.8	-33.3	177.9	-173.9	0	0	0	0	112.4	F35 E97 T101 L102 M149	F35-V99 HydrophobicContact CD1-CG1 3.9Å; F35-V99 HydrophobicContact CE1-CG1 3.42Å; F35-V99 VanDerWaalsContact CE1-CG1 3.42Å; F35-V99 HydrophobicContact CZ-CG1 4.08Å; E97-V99 PolarHBondContact O-N 3.21Å; E97-V99 VanDerWaalsContact O-N 3.14Å; V99-T101 PolarHBondContact O-N 3.07Å; V99-L102 HydrophobicContact CG1-CD1 4.04Å; V99-L102 WeakPolarHBondContact O-CB 2.95Å; V99-L102 WeakPolarHBondContact O-CD1 3.35Å; V99-L102 VanDerWaalsContact O-CG 3.24Å; V99-L102 WeakPolarHBondContact O-CG 3.36Å; V99-L102 PolarHBondContact O-N 2.95Å; V99-L102 VanDerWaalsContact O-N 3.15Å; V99-M149 HydrophobicContact CG2-CE 3.72Å
100	S	80.5	Confident	84.3	Confident	5 Å²	5	33.3 Å²	33.3	4%	0.035	16%	0.162	C	C	.	.	G	3₁₀ helix	trans	-71.4	-11.2	178.8	67.6	0	0	0	0	112.9	S95 E97 V98 L102 M103	S95-S100 WeakPolarHBondContact CB-OG 3.5Å; S95-S100 WeakPolarHBondContact OG-CB 3.48Å; S95-S100 PolarHBondContact OG-OG 3.39Å; E97-S100 PolarHBondContact O-N 3.42Å; E97-S100 PolarHBondContact O-OG 2.96Å; V98-S100 VanDerWaalsContact C-N 3.29Å; V98-S100 PolarHBondContact O-N 3.46Å; S100-L102 PolarHBondContact O-N 3.45Å; S100-L102 VanDerWaalsContact O-N 3.13Å; S100-M103 VanDerWaalsContact O-CB 3.3Å; S100-M103 WeakPolarHBondContact O-CB 3.35Å; S100-M103 VanDerWaalsContact O-CG 3.24Å; S100-M103 WeakPolarHBondContact O-CG 3.31Å; S100-M103 PolarHBondContact O-N 3.04Å
101	T	83.2	Confident	84.5	Confident	0 Å²	0	32.6 Å²	32.6	0%	0	16%	0.158	C	C	.	.	G	3₁₀ helix	trans	-61.4	-16.8	168.9	68.1	0	0	0	0	113.3	V98 V99 M103 L104 F205 Y209	V98-T101 VanDerWaalsContact O-CB 3.26Å; V98-T101 WeakPolarHBondContact O-CB 3.29Å; V98-T101 VanDerWaalsContact O-CG2 3.23Å; V98-T101 WeakPolarHBondContact O-CG2 3.47Å; V98-T101 PolarHBondContact O-N 2.77Å; V98-T101 VanDerWaalsContact O-N 3.1Å; V98-T101 PolarHBondContact O-OG1 3.49Å; V99-T101 PolarHBondContact O-N 3.07Å; T101-M103 PolarHBondContact O-N 3.4Å; T101-L104 VanDerWaalsContact O-CB 3.24Å; T101-L104 WeakPolarHBondContact O-CB 3.47Å; T101-L104 VanDerWaalsContact O-CG 3.28Å; T101-L104 WeakPolarHBondContact O-CG 3.24Å; T101-L104 PolarHBondContact O-N 3.36Å; T101-F205 HydrophobicContact CG2-CD2 4.06Å; T101-F205 HydrophobicContact CG2-CE2 4.02Å; T101-Y209 HydrophobicContact CG2-CD2 4.07Å; T101-Y209 HydrophobicContact CG2-CE1 4.27Å; T101-Y209 HydrophobicContact CG2-CE2 3.19Å; T101-Y209 VanDerWaalsContact CG2-OH 3.22Å; T101-Y209 WeakPolarHBondContact CG2-OH 3.32Å
102	L	86.6	Confident	84.9	Confident	37 Å²	37	31.4 Å²	31.4	19%	0.194	15%	0.147	C	C	.	.	G	3₁₀ helix	trans	-56.2	-19.5	168.4	-69.8	172.7	0	0	0	112.9	V99 S100 L104 E105 L141 F142 L145	V99-L102 HydrophobicContact CG1-CD1 4.04Å; V99-L102 WeakPolarHBondContact O-CB 2.95Å; V99-L102 WeakPolarHBondContact O-CD1 3.35Å; V99-L102 VanDerWaalsContact O-CG 3.24Å; V99-L102 WeakPolarHBondContact O-CG 3.36Å; V99-L102 PolarHBondContact O-N 2.95Å; V99-L102 VanDerWaalsContact O-N 3.15Å; S100-L102 PolarHBondContact O-N 3.45Å; S100-L102 VanDerWaalsContact O-N 3.13Å; L102-L104 PolarHBondContact O-N 3.18Å; L102-L104 VanDerWaalsContact O-N 3.11Å; L102-E105 VanDerWaalsContact O-CB 3.32Å; L102-E105 WeakPolarHBondContact O-CB 3.34Å; L102-E105 PolarHBondContact O-N 3.1Å; L102-L141 HydrophobicContact CD2-CD2 3.62Å; L102-L141 HydrophobicContact CG-CD2 4.35Å; L102-F142 HydrophobicContact CD2-CD1 3.92Å; L102-F142 HydrophobicContact CD2-CE1 3.38Å; L102-F142 HydrophobicContact CD2-CZ 3.89Å; L102-L145 HydrophobicContact CD1-CD1 4.09Å; L102-L145 HydrophobicContact CD2-CD1 3.51Å; L102-L145 HydrophobicContact CG-CD1 3.62Å
103	M	86.4	Confident	85.1	Confident	59 Å²	59	36.9 Å²	36.9	29%	0.291	18%	0.176	S	C	.	.	H	α-helix	trans	-60.2	-17.1	170.8	-63.8	-61.5	167.7	0	0	113.5	L92 S100 T101 E105 Y106 L107	L92-M103 HydrophobicContact CB-CB 4.22Å; L92-M103 HydrophobicContact CD1-CB 3.99Å; S100-M103 VanDerWaalsContact O-CB 3.3Å; S100-M103 WeakPolarHBondContact O-CB 3.35Å; S100-M103 VanDerWaalsContact O-CG 3.24Å; S100-M103 WeakPolarHBondContact O-CG 3.31Å; S100-M103 PolarHBondContact O-N 3.04Å; T101-M103 PolarHBondContact O-N 3.4Å; M103-E105 PolarHBondContact O-N 3.13Å; M103-Y106 PolarHBondContact O-N 3.28Å; M103-Y106 HydrophobicContact SD-CD2 3.65Å; M103-Y106 HydrophobicContact SD-CE2 3.96Å; M103-Y106 HydrophobicContact SD-CG 4.46Å; M103-L107 PolarHBondContact O-N 3.38Å; M103-L107 VanDerWaalsContact O-N 3.09Å
104	L	88.8	Confident	85.4	Confident	0 Å²	0	36.9 Å²	36.9	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-60.6	-28.3	170.4	-73.5	173.1	0	0	0	113.2	L92 T101 L102 G108 L141 V165 K169 A201 F205	L92-L104 HydrophobicContact CD1-CB 4.37Å; L92-L104 HydrophobicContact CD1-CD2 3.53Å; L92-L104 HydrophobicContact CD1-CG 3.61Å; T101-L104 VanDerWaalsContact O-CB 3.24Å; T101-L104 WeakPolarHBondContact O-CB 3.47Å; T101-L104 VanDerWaalsContact O-CG 3.28Å; T101-L104 WeakPolarHBondContact O-CG 3.24Å; T101-L104 PolarHBondContact O-N 3.36Å; L102-L104 PolarHBondContact O-N 3.18Å; L102-L104 VanDerWaalsContact O-N 3.11Å; L104-G108 PolarHBondContact O-N 2.91Å; L104-L141 HydrophobicContact CB-CD1 4.03Å; L104-L141 HydrophobicContact CD1-CD1 3.55Å; L104-L141 HydrophobicContact CG-CD1 4.31Å; L104-V165 HydrophobicContact CD1-CG1 4.4Å; L104-K169 PolarHBondContact O-NZ 3.48Å; L104-A201 HydrophobicContact CD2-CB 3.77Å; L104-F205 HydrophobicContact CD1-CB 4.45Å; L104-F205 HydrophobicContact CD1-CD2 4.1Å; L104-F205 HydrophobicContact CD1-CG 4.32Å
105	E	91	Very high	86	Confident	46 Å²	46	36.3 Å²	36.3	22%	0.215	17%	0.173	C	C	.	.	H	α-helix	trans	-71.4	-45.4	177.7	-165.1	-166.7	147.6	0	0	110.7	L102 M103 L107 G108 L109 R135	L102-E105 VanDerWaalsContact O-CB 3.32Å; L102-E105 WeakPolarHBondContact O-CB 3.34Å; L102-E105 PolarHBondContact O-N 3.1Å; M103-E105 PolarHBondContact O-N 3.13Å; E105-L107 VanDerWaalsContact C-N 3.27Å; E105-L107 PolarHBondContact O-N 3.29Å; E105-G108 PolarHBondContact O-N 2.96Å; E105-G108 VanDerWaalsContact O-N 3.1Å; E105-L109 PolarHBondContact O-N 3.5Å; E105-R135 VanDerWaalsContact CG-NH1 3.34Å; E105-R135 IonicContact OE1-CZ 3.22Å; E105-R135 VanDerWaalsContact OE1-CZ 3.22Å; E105-R135 IonicContact OE1-NH1 2.6Å; E105-R135 PolarHBondContact OE1-NH1 3.05Å; E105-R135 IonicContact OE1-NH2 2.99Å; E105-R135 PolarHBondContact OE1-NH2 3.13Å
106	Y	89.2	Confident	86.6	Confident	131 Å²	131	37.9 Å²	37.9	51%	0.514	18%	0.181	S	C	.	.	H	α-helix	trans	-61.2	-38	174.8	-69	-81.9	0	0	0	111.3	M103 G108 L109 V110	M103-Y106 PolarHBondContact O-N 3.28Å; M103-Y106 HydrophobicContact SD-CD2 3.65Å; M103-Y106 HydrophobicContact SD-CE2 3.96Å; M103-Y106 HydrophobicContact SD-CG 4.46Å; Y106-G108 VanDerWaalsContact C-N 3.31Å; Y106-G108 PolarHBondContact O-N 2.91Å; Y106-L109 PolarHBondContact O-N 3.49Å; Y106-V110 WeakPolarHBondContact O-CG2 3.49Å; Y106-V110 PolarHBondContact O-N 3.03Å
107	L	90.6	Very high	87.4	Confident	0 Å²	0	35.1 Å²	35.1	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-60.9	-40.6	174.9	-170.5	143.5	0	0	0	111.8	F85 V88 M89 M103 E105 S111 L198 A201	F85-L107 HydrophobicContact CE2-CD1 4.47Å; F85-L107 HydrophobicContact CE2-CD2 4.14Å; F85-L107 HydrophobicContact CE2-CG 3.79Å; F85-L107 HydrophobicContact CZ-CD2 4.36Å; F85-L107 HydrophobicContact CZ-CG 4.24Å; V88-L107 HydrophobicContact CG1-CB 4.34Å; M89-L107 HydrophobicContact CB-CD1 4.04Å; M89-L107 HydrophobicContact CG-CD1 4.27Å; M89-L107 HydrophobicContact SD-CD1 3.5Å; M89-L107 VanDerWaalsContact SD-CD1 3.5Å; M103-L107 PolarHBondContact O-N 3.38Å; M103-L107 VanDerWaalsContact O-N 3.09Å; E105-L107 VanDerWaalsContact C-N 3.27Å; E105-L107 PolarHBondContact O-N 3.29Å; L107-S111 WeakPolarHBondContact O-CB 3.23Å; L107-S111 PolarHBondContact O-N 3.5Å; L107-S111 VanDerWaalsContact O-N 3.1Å; L107-L198 HydrophobicContact CD2-CB 3.86Å; L107-L198 HydrophobicContact CD2-CD1 4.35Å; L107-L198 HydrophobicContact CD2-CG 3.62Å; L107-A201 HydrophobicContact CD1-CB 4.47Å
108	G	88.7	Confident	87.8	Confident	2 Å²	2	36.1 Å²	36.1	2%	0.021	17%	0.171	C	C	.	.	H	α-helix	trans	-60.3	-49.1	172.9	0	0	0	0	0	112.4	L104 E105 Y106 S111 F112	L104-G108 PolarHBondContact O-N 2.91Å; E105-G108 PolarHBondContact O-N 2.96Å; E105-G108 VanDerWaalsContact O-N 3.1Å; Y106-G108 VanDerWaalsContact C-N 3.31Å; Y106-G108 PolarHBondContact O-N 2.91Å; G108-S111 PolarHBondContact O-N 3.11Å; G108-S111 PolarHBondContact O-OG 3.3Å; G108-F112 PolarHBondContact O-N 3.04Å; G108-F112 VanDerWaalsContact O-N 3.09Å
109	L	89.5	Confident	88.2	Confident	60 Å²	60	37.5 Å²	37.5	31%	0.314	19%	0.187	S	C	.	.	H	α-helix	trans	-61.9	-45.1	179.5	-74.8	176.9	0	0	0	113.4	E105 Y106 S111 F112 L113 L131	E105-L109 PolarHBondContact O-N 3.5Å; Y106-L109 PolarHBondContact O-N 3.49Å; L109-S111 VanDerWaalsContact C-N 3.31Å; L109-S111 PolarHBondContact O-N 2.93Å; L109-F112 WeakPolarHBondContact O-CB 3.34Å; L109-F112 PolarHBondContact O-N 3.29Å; L109-L113 PolarHBondContact O-N 3.36Å; L109-L131 HydrophobicContact CD2-CD1 4.44Å
110	V	90	Very high	88.6	Confident	29 Å²	29	39.9 Å²	39.9	18%	0.176	20%	0.201	C	C	.	.	H	α-helix	trans	-68.3	-35.3	179.9	-179.5	0	0	0	0	110.7	F85 Y106 F112 L113 L114	F85-V110 HydrophobicContact CB-CG1 3.61Å; F85-V110 HydrophobicContact CD2-CB 3.95Å; F85-V110 HydrophobicContact CD2-CG1 3.74Å; F85-V110 HydrophobicContact CG-CG1 4.14Å; Y106-V110 WeakPolarHBondContact O-CG2 3.49Å; Y106-V110 PolarHBondContact O-N 3.03Å; V110-F112 VanDerWaalsContact C-N 3.32Å; V110-F112 PolarHBondContact O-N 3.13Å; V110-L113 PolarHBondContact O-N 3.31Å; V110-L114 PolarHBondContact O-N 3.08Å; V110-L114 VanDerWaalsContact O-N 3.09Å
111	S	89.8	Confident	89	Confident	3 Å²	3	50.3 Å²	50.3	2%	0.021	24%	0.24	C	C	.	.	H	α-helix	trans	-63.1	-38.9	174.6	78.9	0	0	0	0	112.4	L107 G108 L109 L114 M115	L107-S111 WeakPolarHBondContact O-CB 3.23Å; L107-S111 PolarHBondContact O-N 3.5Å; L107-S111 VanDerWaalsContact O-N 3.1Å; G108-S111 PolarHBondContact O-N 3.11Å; G108-S111 PolarHBondContact O-OG 3.3Å; L109-S111 VanDerWaalsContact C-N 3.31Å; L109-S111 PolarHBondContact O-N 2.93Å; S111-L114 PolarHBondContact O-N 2.96Å; S111-M115 VanDerWaalsContact O-CE 3.25Å; S111-M115 WeakPolarHBondContact O-CE 3.45Å; S111-M115 PolarHBondContact O-N 3.38Å
112	F	90	Very high	89.1	Confident	42 Å²	42	52.8 Å²	52.8	18%	0.184	26%	0.257	C	S	.	.	H	α-helix	trans	-58	-49.5	173.6	168.9	-107.2	0	0	0	111.5	G108 L109 V110 L114 M115 L116 G127 L131	G108-F112 PolarHBondContact O-N 3.04Å; G108-F112 VanDerWaalsContact O-N 3.09Å; L109-F112 WeakPolarHBondContact O-CB 3.34Å; L109-F112 PolarHBondContact O-N 3.29Å; V110-F112 VanDerWaalsContact C-N 3.32Å; V110-F112 PolarHBondContact O-N 3.13Å; F112-L114 VanDerWaalsContact C-N 3.28Å; F112-L114 PolarHBondContact O-N 3.33Å; F112-M115 PolarHBondContact O-N 3.45Å; F112-M115 VanDerWaalsContact O-N 3.16Å; F112-L116 HydrophobicContact CD1-CD1 4.29Å; F112-L116 HydrophobicContact CE1-CD1 3.63Å; F112-L116 HydrophobicContact CE1-CG 4.5Å; F112-L116 HydrophobicContact CE2-CD1 3.97Å; F112-L116 HydrophobicContact CE2-CD2 4.3Å; F112-L116 HydrophobicContact CE2-CG 4.19Å; F112-L116 HydrophobicContact CZ-CD1 3.48Å; F112-L116 VanDerWaalsContact CZ-CD1 3.48Å; F112-L116 HydrophobicContact CZ-CG 4.2Å; F112-L116 WeakPolarHBondContact O-CG 3.43Å; F112-L116 PolarHBondContact O-N 3.49Å; F112-G127 VanDerWaalsContact CD2-C 3.48Å; F112-G127 WeakPolarHBondContact CD2-O 3.42Å; F112-L131 HydrophobicContact CB-CD1 4.15Å; F112-L131 HydrophobicContact CD1-CD1 3.84Å; F112-L131 HydrophobicContact CD2-CB 3.98Å; F112-L131 HydrophobicContact CD2-CD1 3.88Å; F112-L131 HydrophobicContact CE1-CD1 4.11Å; F112-L131 HydrophobicContact CE2-CB 4.49Å; F112-L131 HydrophobicContact CE2-CD1 4.14Å; F112-L131 HydrophobicContact CG-CB 4.37Å; F112-L131 HydrophobicContact CG-CD1 3.68Å; F112-L131 HydrophobicContact CZ-CD1 4.23Å
113	L	90.5	Very high	89.1	Confident	115 Å²	115	51.3 Å²	51.3	60%	0.602	25%	0.25	S	S	*	.	H	α-helix	trans	-60.1	-38.6	178.5	-66.4	175.5	0	0	0	112.3	L109 V110 L116	L109-L113 PolarHBondContact O-N 3.36Å; V110-L113 PolarHBondContact O-N 3.31Å; L113-L116 PolarHBondContact O-N 3.07Å
114	L	91	Very high	89.2	Confident	4 Å²	4	53.4 Å²	53.4	2%	0.021	26%	0.256	C	S	.	.	H	α-helix	trans	-65.3	-37.7	176.5	-76.7	170.7	0	0	0	113	L78 S81 M82 F85 V110 S111 F112 L116 Y117 V189 V193	L78-L114 HydrophobicContact CD1-CD2 4.41Å; S81-L114 WeakPolarHBondContact OG-CD2 3.29Å; M82-L114 HydrophobicContact CG-CD2 4.11Å; F85-L114 HydrophobicContact CB-CD1 3.76Å; F85-L114 HydrophobicContact CD1-CD1 4.26Å; F85-L114 HydrophobicContact CD2-CD1 4.13Å; F85-L114 HydrophobicContact CG-CD1 3.8Å; V110-L114 PolarHBondContact O-N 3.08Å; V110-L114 VanDerWaalsContact O-N 3.09Å; S111-L114 PolarHBondContact O-N 2.96Å; F112-L114 VanDerWaalsContact C-N 3.28Å; F112-L114 PolarHBondContact O-N 3.33Å; L114-L116 VanDerWaalsContact C-N 3.29Å; L114-L116 PolarHBondContact O-N 3.13Å; L114-Y117 WeakPolarHBondContact O-CB 3.4Å; L114-Y117 PolarHBondContact O-N 2.87Å; L114-V189 HydrophobicContact CB-CG1 3.84Å; L114-V189 HydrophobicContact CB-CG2 4.47Å; L114-V189 HydrophobicContact CD1-CG1 4.35Å; L114-V189 HydrophobicContact CD2-CG2 4.07Å; L114-V193 HydrophobicContact CD1-CG2 4.06Å
115	M	90.3	Very high	89.1	Confident	6 Å²	6	60.2 Å²	60.2	3%	0.03	28%	0.281	C	S	.	.	H	α-helix	trans	-67.6	-30	177	-78.2	-179.5	-83.4	0	0	112.8	S111 F112 Y117 T130 A182 A185	S111-M115 VanDerWaalsContact O-CE 3.25Å; S111-M115 WeakPolarHBondContact O-CE 3.45Å; S111-M115 PolarHBondContact O-N 3.38Å; F112-M115 PolarHBondContact O-N 3.45Å; F112-M115 VanDerWaalsContact O-N 3.16Å; M115-Y117 PolarHBondContact O-N 3.3Å; M115-T130 VanDerWaalsContact CE-CB 3.49Å; M115-T130 HydrophobicContact CE-CG2 3.7Å; M115-T130 WeakPolarHBondContact CE-OG1 3.48Å; M115-T130 HydrophobicContact SD-CG2 3.55Å; M115-T130 VanDerWaalsContact SD-CG2 3.55Å; M115-T130 PolarHBondContact SD-OG1 3.39Å; M115-A182 HydrophobicContact SD-CB 3.58Å; M115-A182 VanDerWaalsContact SD-CB 3.58Å; M115-A185 HydrophobicContact CG-CB 4.17Å
116	L	90.5	Very high	88.8	Confident	37 Å²	37	58.1 Å²	58.1	19%	0.194	27%	0.272	C	S	.	.	G	3₁₀ helix	trans	-75	-2.4	178.9	-66.3	-171	0	0	0	114.5	F112 L113 L114 Y118 G119 Y124	F112-L116 HydrophobicContact CD1-CD1 4.29Å; F112-L116 HydrophobicContact CE1-CD1 3.63Å; F112-L116 HydrophobicContact CE1-CG 4.5Å; F112-L116 HydrophobicContact CE2-CD1 3.97Å; F112-L116 HydrophobicContact CE2-CD2 4.3Å; F112-L116 HydrophobicContact CE2-CG 4.19Å; F112-L116 HydrophobicContact CZ-CD1 3.48Å; F112-L116 VanDerWaalsContact CZ-CD1 3.48Å; F112-L116 HydrophobicContact CZ-CG 4.2Å; F112-L116 WeakPolarHBondContact O-CG 3.43Å; F112-L116 PolarHBondContact O-N 3.49Å; L113-L116 PolarHBondContact O-N 3.07Å; L114-L116 VanDerWaalsContact C-N 3.29Å; L114-L116 PolarHBondContact O-N 3.13Å; L116-Y118 VanDerWaalsContact C-N 3.33Å; L116-Y118 PolarHBondContact O-N 2.95Å; L116-G119 PolarHBondContact O-N 2.68Å; L116-Y124 HydrophobicContact CD1-CD1 4.41Å; L116-Y124 HydrophobicContact CD1-CE1 4.31Å; L116-Y124 HydrophobicContact CD2-CD1 3.34Å; L116-Y124 HydrophobicContact CD2-CE1 3.8Å; L116-Y124 HydrophobicContact CD2-CG 4.14Å; L116-Y124 HydrophobicContact CG-CD1 4.41Å; L116-Y124 HydrophobicContact CG-CE1 4.5Å
117	Y	90	Very high	88.7	Confident	58 Å²	58	51.9 Å²	51.9	23%	0.227	25%	0.247	C	C	.	.	G	3₁₀ helix	trans	-52.5	-43.2	-171.3	-179.7	-99.4	0	0	0	114.8	L69 Y74 I77 L78 L114 M115 G119 P186	L69-Y117 HydrophobicContact CD1-CE1 4.04Å; Y74-Y117 VanDerWaalsContact C-OH 3.24Å; Y74-Y117 WeakPolarHBondContact CA-OH 3.35Å; Y74-Y117 WeakPolarHBondContact CB-OH 3.3Å; Y74-Y117 PolarHBondContact O-OH 3.38Å; I77-Y117 HydrophobicContact CG2-CE2 4.47Å; L78-Y117 HydrophobicContact CB-CD2 4.45Å; L78-Y117 HydrophobicContact CB-CE2 3.9Å; L78-Y117 HydrophobicContact CD1-CD1 4.16Å; L78-Y117 HydrophobicContact CD1-CD2 3.72Å; L78-Y117 HydrophobicContact CD1-CE1 4.43Å; L78-Y117 HydrophobicContact CD1-CE2 4.02Å; L78-Y117 HydrophobicContact CD1-CG 3.79Å; L114-Y117 WeakPolarHBondContact O-CB 3.4Å; L114-Y117 PolarHBondContact O-N 2.87Å; M115-Y117 PolarHBondContact O-N 3.3Å; Y117-G119 VanDerWaalsContact C-N 3.31Å; Y117-G119 PolarHBondContact O-N 3.24Å; Y117-P186 HydrophobicContact CD1-CG 4.13Å
118	Y	87	Confident	88.6	Confident	92 Å²	92	55.7 Å²	55.7	36%	0.361	27%	0.27	S	S	.	.	G	3₁₀ helix	trans	-75.6	-15.5	179.7	-73.1	-44.6	0	0	0	114.2	L116 V120 P186	L116-Y118 VanDerWaalsContact C-N 3.33Å; L116-Y118 PolarHBondContact O-N 2.95Å; Y118-V120 PolarHBondContact O-N 2.83Å; Y118-V120 VanDerWaalsContact O-N 3.16Å; Y118-P186 HydrophobicContact CE2-CB 4.01Å; Y118-P186 HydrophobicContact CE2-CG 4.42Å
119	G	87.3	Confident	88.5	Confident	36 Å²	36	57.9 Å²	57.9	37%	0.371	28%	0.283	S	S	.	.			trans	61.7	21.5	179.3	0	0	0	0	0	115.3	L116 Y117 Y124	L116-G119 PolarHBondContact O-N 2.68Å; Y117-G119 VanDerWaalsContact C-N 3.31Å; Y117-G119 PolarHBondContact O-N 3.24Å; G119-Y124 VanDerWaalsContact C-CE2 3.42Å; G119-Y124 WeakPolarHBondContact O-CE2 3.3Å
120	V	89.7	Confident	88.3	Confident	76 Å²	76	55.2 Å²	55.2	46%	0.461	27%	0.27	S	S	.	.			trans	-92.3	145.3	177.6	-177.9	0	0	0	0	110.3	Y118 S122 C123 Y124	Y118-V120 PolarHBondContact O-N 2.83Å; Y118-V120 VanDerWaalsContact O-N 3.16Å; V120-S122 PolarHBondContact O-N 3.27Å; V120-S122 VanDerWaalsContact O-N 3.1Å; V120-C123 WeakPolarHBondContact O-CA 3.43Å; V120-C123 WeakPolarHBondContact O-CB 3.11Å; V120-C123 PolarHBondContact O-N 3.44Å; V120-Y124 VanDerWaalsContact O-CD2 3.26Å; V120-Y124 WeakPolarHBondContact O-CD2 3.5Å; V120-Y124 PolarHBondContact O-N 2.84Å
121	W	88.2	Confident	88.2	Confident	224 Å²	224	55.9 Å²	55.9	85%	0.848	27%	0.272	S	S	*	.	H	α-helix	trans	-46	-41.1	176.3	-78.4	108.7	0	0	0	114.4	C123 Y124 R125	W121-C123 VanDerWaalsContact C-N 3.35Å; W121-C123 PolarHBondContact O-N 3.27Å; W121-Y124 PolarHBondContact O-N 3.23Å; W121-R125 PolarHBondContact O-N 3.11Å; W121-R125 VanDerWaalsContact O-N 3.09Å
122	S	85.5	Confident	88.2	Confident	51 Å²	51	59.6 Å²	59.6	36%	0.357	29%	0.294	S	S	.	.	H	α-helix	trans	-64.8	-37.6	176.6	63.1	0	0	0	0	112.3	V120 G126 R184	V120-S122 PolarHBondContact O-N 3.27Å; V120-S122 VanDerWaalsContact O-N 3.1Å; S122-G126 PolarHBondContact O-N 3.35Å; S122-R184 VanDerWaalsContact C-CD 3.5Å; S122-R184 WeakPolarHBondContact O-CD 3.37Å; S122-R184 PolarHBondContact O-NH1 2.65Å
123	C	87.1	Confident	88	Confident	7 Å²	7	58.3 Å²	58.3	5%	0.047	29%	0.291	C	S	.	.	H	α-helix	trans	-71.3	-38.8	176.2	-60.9	0	0	0	0	111.5	V120 W121 R125 G126 G127	V120-C123 WeakPolarHBondContact O-CA 3.43Å; V120-C123 WeakPolarHBondContact O-CB 3.11Å; V120-C123 PolarHBondContact O-N 3.44Å; W121-C123 VanDerWaalsContact C-N 3.35Å; W121-C123 PolarHBondContact O-N 3.27Å; C123-R125 PolarHBondContact O-N 3.23Å; C123-G126 PolarHBondContact O-N 3.23Å; C123-G127 PolarHBondContact O-N 3.37Å
124	Y	88.8	Confident	87.8	Confident	103 Å²	103	53.3 Å²	53.3	40%	0.404	27%	0.265	S	S	.	.	H	α-helix	trans	-58.7	-47	174.1	-71.9	-67	0	0	0	112.1	L116 G119 V120 W121 G126 G127 V128	L116-Y124 HydrophobicContact CD1-CD1 4.41Å; L116-Y124 HydrophobicContact CD1-CE1 4.31Å; L116-Y124 HydrophobicContact CD2-CD1 3.34Å; L116-Y124 HydrophobicContact CD2-CE1 3.8Å; L116-Y124 HydrophobicContact CD2-CG 4.14Å; L116-Y124 HydrophobicContact CG-CD1 4.41Å; L116-Y124 HydrophobicContact CG-CE1 4.5Å; G119-Y124 VanDerWaalsContact C-CE2 3.42Å; G119-Y124 WeakPolarHBondContact O-CE2 3.3Å; V120-Y124 VanDerWaalsContact O-CD2 3.26Å; V120-Y124 WeakPolarHBondContact O-CD2 3.5Å; V120-Y124 PolarHBondContact O-N 2.84Å; W121-Y124 PolarHBondContact O-N 3.23Å; Y124-G126 VanDerWaalsContact C-N 3.31Å; Y124-G126 PolarHBondContact O-N 3.47Å; Y124-G127 PolarHBondContact O-N 3.03Å; Y124-V128 WeakPolarHBondContact O-CG2 3.47Å; Y124-V128 PolarHBondContact O-N 3.45Å
125	R	87.1	Confident	87.8	Confident	143 Å²	143	56.9 Å²	56.9	54%	0.54	28%	0.278	S	S	.	.	H	α-helix	trans	-57.5	-45.3	175.9	-179.5	179.1	173.3	-178	-1.5	111.5	W121 C123 V128 V129	W121-R125 PolarHBondContact O-N 3.11Å; W121-R125 VanDerWaalsContact O-N 3.09Å; C123-R125 PolarHBondContact O-N 3.23Å; R125-V128 PolarHBondContact O-N 3.01Å; R125-V129 WeakPolarHBondContact O-CG2 3.49Å; R125-V129 PolarHBondContact O-N 2.97Å; R125-V129 VanDerWaalsContact O-N 3.15Å
126	G	83.4	Confident	87.7	Confident	1 Å²	1	60 Å²	60	1%	0.01	29%	0.292	C	S	.	.	H	α-helix	trans	-65.2	-43.1	178.8	0	0	0	0	0	112.7	S122 C123 Y124 V128 V129 T130	S122-G126 PolarHBondContact O-N 3.35Å; C123-G126 PolarHBondContact O-N 3.23Å; Y124-G126 VanDerWaalsContact C-N 3.31Å; Y124-G126 PolarHBondContact O-N 3.47Å; G126-V128 PolarHBondContact O-N 2.85Å; G126-V129 PolarHBondContact O-N 3.05Å; G126-T130 WeakPolarHBondContact O-CG2 3.49Å; G126-T130 PolarHBondContact O-N 2.99Å; G126-T130 PolarHBondContact O-OG1 3.07Å
127	G	87.1	Confident	87.8	Confident	0 Å²	0	58.2 Å²	58.2	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-57.9	-44.8	174.1	0	0	0	0	0	112.7	F112 C123 Y124 T130 L131	F112-G127 VanDerWaalsContact CD2-C 3.48Å; F112-G127 WeakPolarHBondContact CD2-O 3.42Å; C123-G127 PolarHBondContact O-N 3.37Å; Y124-G127 PolarHBondContact O-N 3.03Å; G127-T130 WeakPolarHBondContact CA-OG1 3.47Å; G127-T130 PolarHBondContact O-N 3.36Å; G127-T130 PolarHBondContact O-OG1 2.93Å; G127-L131 WeakPolarHBondContact O-CB 3.48Å; G127-L131 PolarHBondContact O-N 3.11Å
128	V	88.2	Confident	87.9	Confident	81 Å²	81	55.7 Å²	55.7	49%	0.491	27%	0.273	S	S	.	.	H	α-helix	trans	-65.7	-44	179.6	174.3	0	0	0	0	111.7	Y124 R125 G126 T130 L131 V132	Y124-V128 WeakPolarHBondContact O-CG2 3.47Å; Y124-V128 PolarHBondContact O-N 3.45Å; R125-V128 PolarHBondContact O-N 3.01Å; G126-V128 PolarHBondContact O-N 2.85Å; V128-T130 VanDerWaalsContact C-N 3.32Å; V128-T130 PolarHBondContact O-N 2.85Å; V128-L131 PolarHBondContact O-N 3.21Å; V128-V132 HydrophobicContact CG1-CG2 4.28Å; V128-V132 WeakPolarHBondContact O-CG2 3.26Å; V128-V132 PolarHBondContact O-N 2.97Å
129	V	87	Confident	88.2	Confident	48 Å²	48	55.1 Å²	55.1	29%	0.291	28%	0.279	S	S	.	.	H	α-helix	trans	-59.7	-43.7	178.6	172.3	0	0	0	0	111.3	R125 G126 S133 W178	R125-V129 WeakPolarHBondContact O-CG2 3.49Å; R125-V129 PolarHBondContact O-N 2.97Å; R125-V129 VanDerWaalsContact O-N 3.15Å; G126-V129 PolarHBondContact O-N 3.05Å; V129-S133 WeakPolarHBondContact O-CB 3.02Å; V129-S133 PolarHBondContact O-N 3.35Å; V129-S133 PolarHBondContact O-OG 3.48Å; V129-W178 HydrophobicContact CG1-CB 4.15Å
130	T	85.6	Confident	88.4	Confident	4 Å²	4	53.6 Å²	53.6	3%	0.025	26%	0.263	C	S	.	.	H	α-helix	trans	-68	-38	177.9	52.7	0	0	0	0	113.5	M115 G126 G127 V128 S133 S134 W178 A182	M115-T130 VanDerWaalsContact CE-CB 3.49Å; M115-T130 HydrophobicContact CE-CG2 3.7Å; M115-T130 WeakPolarHBondContact CE-OG1 3.48Å; M115-T130 HydrophobicContact SD-CG2 3.55Å; M115-T130 VanDerWaalsContact SD-CG2 3.55Å; M115-T130 PolarHBondContact SD-OG1 3.39Å; G126-T130 WeakPolarHBondContact O-CG2 3.49Å; G126-T130 PolarHBondContact O-N 2.99Å; G126-T130 PolarHBondContact O-OG1 3.07Å; G127-T130 WeakPolarHBondContact CA-OG1 3.47Å; G127-T130 PolarHBondContact O-N 3.36Å; G127-T130 PolarHBondContact O-OG1 2.93Å; V128-T130 VanDerWaalsContact C-N 3.32Å; V128-T130 PolarHBondContact O-N 2.85Å; T130-S133 PolarHBondContact O-OG 2.96Å; T130-S133 VanDerWaalsContact O-OG 3.06Å; T130-S134 WeakPolarHBondContact O-CB 3.48Å; T130-S134 PolarHBondContact O-N 3.01Å; T130-S134 PolarHBondContact O-OG 2.92Å; T130-W178 HydrophobicContact CG2-CB 3.99Å; T130-W178 HydrophobicContact CG2-CD2 4.5Å; T130-W178 HydrophobicContact CG2-CE3 3.77Å; T130-W178 WeakPolarHBondContact CG2-O 3.31Å; T130-A182 HydrophobicContact CG2-CB 3.91Å
131	L	88.9	Confident	88.5	Confident	43 Å²	43	50.1 Å²	50.1	23%	0.225	24%	0.241	C	C	.	.	H	α-helix	trans	-63.4	-51.9	174.9	-173.6	151	0	0	0	109.9	L109 F112 G127 V128 S133 S134 R135	L109-L131 HydrophobicContact CD2-CD1 4.44Å; F112-L131 HydrophobicContact CB-CD1 4.15Å; F112-L131 HydrophobicContact CD1-CD1 3.84Å; F112-L131 HydrophobicContact CD2-CB 3.98Å; F112-L131 HydrophobicContact CD2-CD1 3.88Å; F112-L131 HydrophobicContact CE1-CD1 4.11Å; F112-L131 HydrophobicContact CE2-CB 4.49Å; F112-L131 HydrophobicContact CE2-CD1 4.14Å; F112-L131 HydrophobicContact CG-CB 4.37Å; F112-L131 HydrophobicContact CG-CD1 3.68Å; F112-L131 HydrophobicContact CZ-CD1 4.23Å; G127-L131 WeakPolarHBondContact O-CB 3.48Å; G127-L131 PolarHBondContact O-N 3.11Å; V128-L131 PolarHBondContact O-N 3.21Å; L131-S133 PolarHBondContact O-N 3.3Å; L131-S134 PolarHBondContact O-N 2.9Å; L131-S134 PolarHBondContact O-OG 3.47Å; L131-R135 HydrophobicContact CD2-CG 3.91Å; L131-R135 VanDerWaalsContact O-CG 3.28Å; L131-R135 WeakPolarHBondContact O-CG 3.24Å; L131-R135 PolarHBondContact O-N 3.19Å
132	V	88.4	Confident	88.8	Confident	80 Å²	80	44.1 Å²	44.1	49%	0.485	22%	0.222	S	C	.	.	H	α-helix	trans	-60.6	-44.6	-178.1	173.7	0	0	0	0	111.7	V128 S134 R135 F136	V128-V132 HydrophobicContact CG1-CG2 4.28Å; V128-V132 WeakPolarHBondContact O-CG2 3.26Å; V128-V132 PolarHBondContact O-N 2.97Å; V132-S134 VanDerWaalsContact C-N 3.34Å; V132-S134 PolarHBondContact O-N 2.76Å; V132-R135 PolarHBondContact O-N 2.97Å; V132-F136 PolarHBondContact O-N 3.41Å
133	S	86.7	Confident	89.1	Confident	16 Å²	16	47.1 Å²	47.1	11%	0.112	23%	0.228	C	C	.	.	H	α-helix	trans	-63.3	-39.9	177.8	67.2	0	0	0	0	112.3	V129 T130 L131 F136 W178	V129-S133 WeakPolarHBondContact O-CB 3.02Å; V129-S133 PolarHBondContact O-N 3.35Å; V129-S133 PolarHBondContact O-OG 3.48Å; T130-S133 PolarHBondContact O-OG 2.96Å; T130-S133 VanDerWaalsContact O-OG 3.06Å; L131-S133 PolarHBondContact O-N 3.3Å; S133-F136 PolarHBondContact O-N 2.92Å; S133-W178 VanDerWaalsContact OG-CB 3.29Å; S133-W178 WeakPolarHBondContact OG-CB 3.42Å; S133-W178 VanDerWaalsContact OG-CG 3.28Å
134	S	87	Confident	89.3	Confident	10 Å²	10	46.8 Å²	46.8	7%	0.07	23%	0.226	C	C	.	.	H	α-helix	trans	-65.8	-38.3	177.7	72.7	0	0	0	0	112.4	T130 L131 V132 F136 G137 D138	T130-S134 WeakPolarHBondContact O-CB 3.48Å; T130-S134 PolarHBondContact O-N 3.01Å; T130-S134 PolarHBondContact O-OG 2.92Å; L131-S134 PolarHBondContact O-N 2.9Å; L131-S134 PolarHBondContact O-OG 3.47Å; V132-S134 VanDerWaalsContact C-N 3.34Å; V132-S134 PolarHBondContact O-N 2.76Å; S134-F136 VanDerWaalsContact C-N 3.32Å; S134-F136 PolarHBondContact O-N 3.49Å; S134-G137 PolarHBondContact O-N 3.17Å; S134-G137 VanDerWaalsContact O-N 3.14Å; S134-D138 PolarHBondContact O-N 2.98Å
135	R	89.9	Confident	89.3	Confident	78 Å²	78	42.6 Å²	42.6	29%	0.294	21%	0.211	S	C	.	.	H	α-helix	trans	-65.1	-33.8	178.2	-69.5	-58	-175.5	163.1	-12	113.2	E105 L131 V132 G137 D138 V139	E105-R135 VanDerWaalsContact CG-NH1 3.34Å; E105-R135 IonicContact OE1-CZ 3.22Å; E105-R135 VanDerWaalsContact OE1-CZ 3.22Å; E105-R135 IonicContact OE1-NH1 2.6Å; E105-R135 PolarHBondContact OE1-NH1 3.05Å; E105-R135 IonicContact OE1-NH2 2.99Å; E105-R135 PolarHBondContact OE1-NH2 3.13Å; L131-R135 HydrophobicContact CD2-CG 3.91Å; L131-R135 VanDerWaalsContact O-CG 3.28Å; L131-R135 WeakPolarHBondContact O-CG 3.24Å; L131-R135 PolarHBondContact O-N 3.19Å; V132-R135 PolarHBondContact O-N 2.97Å; R135-G137 VanDerWaalsContact C-N 3.27Å; R135-G137 PolarHBondContact O-N 2.96Å; R135-D138 PolarHBondContact O-N 3.27Å; R135-V139 WeakPolarHBondContact O-CG2 3.48Å; R135-V139 PolarHBondContact O-N 2.98Å
136	F	89.1	Confident	89.5	Confident	71 Å²	71	38.1 Å²	38.1	31%	0.311	20%	0.204	S	C	.	.	H	α-helix	trans	-60.7	-39.4	173.8	-169	-100.1	0	0	0	111.8	V132 S133 S134 L164 T168 F175 W486	V132-F136 PolarHBondContact O-N 3.41Å; S133-F136 PolarHBondContact O-N 2.92Å; S134-F136 VanDerWaalsContact C-N 3.32Å; S134-F136 PolarHBondContact O-N 3.49Å; F136-L164 HydrophobicContact CE1-CD1 4.32Å; F136-L164 HydrophobicContact CE1-CD2 3.95Å; F136-T168 HydrophobicContact CB-CG2 4.38Å; F136-T168 HydrophobicContact CD1-CG2 3.91Å; F136-F175 AromaticContact CD1-CE1 3.95Å; F136-F175 HydrophobicContact CD1-CE1 3.95Å; F136-F175 HydrophobicContact CD1-CE2 4.28Å; F136-F175 AromaticContact CD1-CZ 3.57Å; F136-F175 HydrophobicContact CD1-CZ 3.57Å; F136-F175 HydrophobicContact CE1-CE1 4.23Å; F136-F175 HydrophobicContact CE1-CE2 4.2Å; F136-F175 AromaticContact CE1-CZ 3.49Å; F136-F175 HydrophobicContact CE1-CZ 3.49Å; F136-F175 VanDerWaalsContact CE1-CZ 3.49Å; F136-F175 HydrophobicContact CZ-CZ 4.41Å; F136-W486 HydrophobicContact CD2-CZ3 4.24Å; F136-W486 HydrophobicContact CE2-CH2 4.05Å; F136-W486 AromaticContact CE2-CZ3 3.68Å; F136-W486 HydrophobicContact CE2-CZ3 3.68Å; F136-W486 HydrophobicContact CZ-CH2 4.13Å; F136-W486 HydrophobicContact CZ-CZ3 4.13Å
137	G	91.2	Very high	89.8	Confident	0 Å²	0	40.3 Å²	40.3	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-66.3	-42.8	172.9	0	0	0	0	0	112.8	S134 R135 V139 A140 L141 T168	S134-G137 PolarHBondContact O-N 3.17Å; S134-G137 VanDerWaalsContact O-N 3.14Å; R135-G137 VanDerWaalsContact C-N 3.27Å; R135-G137 PolarHBondContact O-N 2.96Å; G137-V139 VanDerWaalsContact C-N 3.29Å; G137-V139 PolarHBondContact O-N 3.47Å; G137-A140 WeakPolarHBondContact O-CB 3.15Å; G137-A140 PolarHBondContact O-N 2.94Å; G137-L141 PolarHBondContact O-N 3.31Å; G137-T168 WeakPolarHBondContact CA-OG1 3.3Å
138	D	92	Very high	89.7	Confident	5 Å²	5	45.3 Å²	45.3	3%	0.027	23%	0.233	C	C	.	.	H	α-helix	trans	-64	-34.4	-178.4	-57.4	-28.5	0	0	0	111.8	S134 R135 A140 L141 F142 K169	S134-D138 PolarHBondContact O-N 2.98Å; R135-D138 PolarHBondContact O-N 3.27Å; D138-A140 VanDerWaalsContact C-N 3.33Å; D138-A140 PolarHBondContact O-N 3.44Å; D138-L141 WeakPolarHBondContact O-CB 3.47Å; D138-L141 PolarHBondContact O-N 3.32Å; D138-L141 VanDerWaalsContact O-N 3.17Å; D138-F142 WeakPolarHBondContact O-CD2 3.25Å; D138-F142 PolarHBondContact O-N 2.96Å; D138-K169 WeakPolarHBondContact OD1-CE 3.46Å; D138-K169 IonicContact OD1-NZ 2.75Å; D138-K169 PolarHBondContact OD1-NZ 3.44Å; D138-K169 IonicContact OD2-NZ 3.72Å
139	V	93.2	Very high	89.6	Confident	80 Å²	80	47.2 Å²	47.2	49%	0.485	24%	0.238	S	C	.	.	H	α-helix	trans	-60	-43.2	171.7	173.1	0	0	0	0	111.4	R135 G137 L141 F142 F143	R135-V139 WeakPolarHBondContact O-CG2 3.48Å; R135-V139 PolarHBondContact O-N 2.98Å; G137-V139 VanDerWaalsContact C-N 3.29Å; G137-V139 PolarHBondContact O-N 3.47Å; V139-L141 VanDerWaalsContact C-N 3.3Å; V139-L141 PolarHBondContact O-N 2.72Å; V139-F142 PolarHBondContact O-N 2.98Å; V139-F143 HydrophobicContact CG1-CD2 4.04Å; V139-F143 HydrophobicContact CG1-CE2 3.67Å; V139-F143 WeakPolarHBondContact O-CD2 3.41Å; V139-F143 PolarHBondContact O-N 3.42Å
140	A	93	Very high	89.6	Confident	4 Å²	4	49.2 Å²	49.2	3%	0.033	25%	0.251	C	S	.	.	H	α-helix	trans	-65.9	-33.7	176.2	0	0	0	0	0	112.3	G137 D138 F143 L144 C161 L164 V165	G137-A140 WeakPolarHBondContact O-CB 3.15Å; G137-A140 PolarHBondContact O-N 2.94Å; D138-A140 VanDerWaalsContact C-N 3.33Å; D138-A140 PolarHBondContact O-N 3.44Å; A140-F143 PolarHBondContact O-N 3.32Å; A140-L144 WeakPolarHBondContact O-CB 3.37Å; A140-L144 PolarHBondContact O-N 3.23Å; A140-C161 HydrophobicContact CB-CB 4.44Å; A140-L164 HydrophobicContact CB-CB 3.73Å; A140-L164 HydrophobicContact CB-CD1 4.17Å; A140-V165 HydrophobicContact CB-CG2 4.03Å
141	L	92	Very high	89.5	Confident	3 Å²	3	52.3 Å²	52.3	2%	0.016	28%	0.283	C	S	.	.	H	α-helix	trans	-63.3	-43.5	173.6	-172.1	162.8	0	0	0	111.3	L102 L104 G137 D138 V139 F143 L144 L145 V165	L102-L141 HydrophobicContact CD2-CD2 3.62Å; L102-L141 HydrophobicContact CG-CD2 4.35Å; L104-L141 HydrophobicContact CB-CD1 4.03Å; L104-L141 HydrophobicContact CD1-CD1 3.55Å; L104-L141 HydrophobicContact CG-CD1 4.31Å; G137-L141 PolarHBondContact O-N 3.31Å; D138-L141 WeakPolarHBondContact O-CB 3.47Å; D138-L141 PolarHBondContact O-N 3.32Å; D138-L141 VanDerWaalsContact O-N 3.17Å; V139-L141 VanDerWaalsContact C-N 3.3Å; V139-L141 PolarHBondContact O-N 2.72Å; L141-F143 PolarHBondContact O-N 3.18Å; L141-L144 WeakPolarHBondContact O-CB 3.31Å; L141-L144 PolarHBondContact O-N 3.17Å; L141-L144 VanDerWaalsContact O-N 3.17Å; L141-L145 HydrophobicContact CD2-CD1 3.43Å; L141-L145 VanDerWaalsContact CD2-CD1 3.43Å; L141-L145 HydrophobicContact CD2-CG 3.95Å; L141-L145 WeakPolarHBondContact O-CG 3.28Å; L141-L145 PolarHBondContact O-N 3.47Å; L141-V165 HydrophobicContact CB-CG2 3.91Å
142	F	92.8	Very high	89.2	Confident	99 Å²	99	54 Å²	54	43%	0.434	30%	0.298	S	S	.	.	H	α-helix	trans	-60.8	-42.4	175.4	-74.9	-66.5	0	0	0	112.8	L102 D138 V139 L144 L145 A146	L102-F142 HydrophobicContact CD2-CD1 3.92Å; L102-F142 HydrophobicContact CD2-CE1 3.38Å; L102-F142 HydrophobicContact CD2-CZ 3.89Å; D138-F142 WeakPolarHBondContact O-CD2 3.25Å; D138-F142 PolarHBondContact O-N 2.96Å; V139-F142 PolarHBondContact O-N 2.98Å; F142-L144 VanDerWaalsContact C-N 3.31Å; F142-L144 PolarHBondContact O-N 3.5Å; F142-L145 PolarHBondContact O-N 3.24Å; F142-A146 WeakPolarHBondContact O-CB 3.43Å; F142-A146 PolarHBondContact O-N 3.42Å
143	F	92	Very high	88.8	Confident	113 Å²	113	51.7 Å²	51.7	50%	0.496	29%	0.291	S	S	.	.	H	α-helix	trans	-62.5	-40.8	174.1	-76.4	-63.5	0	0	0	112.1	V139 A140 L141 A146 F147	V139-F143 HydrophobicContact CG1-CD2 4.04Å; V139-F143 HydrophobicContact CG1-CE2 3.67Å; V139-F143 WeakPolarHBondContact O-CD2 3.41Å; V139-F143 PolarHBondContact O-N 3.42Å; A140-F143 PolarHBondContact O-N 3.32Å; L141-F143 PolarHBondContact O-N 3.18Å; F143-A146 WeakPolarHBondContact O-CB 3.17Å; F143-A146 PolarHBondContact O-N 2.95Å; F143-F147 HydrophobicContact CB-CE2 4.22Å; F143-F147 WeakPolarHBondContact O-CD2 3.39Å; F143-F147 VanDerWaalsContact O-CG 3.31Å; F143-F147 WeakPolarHBondContact O-CG 3.42Å; F143-F147 PolarHBondContact O-N 3.38Å
144	L	90.9	Very high	88.8	Confident	0 Å²	0	54 Å²	54	0%	0	31%	0.307	C	S	.	.	H	α-helix	trans	-62.5	-44.5	177.7	-173.9	140.9	0	0	0	112.2	V98 A140 L141 F142 A146 F147 Y148 C161 M162 F205 M213	V98-L144 HydrophobicContact CG1-CD2 4.45Å; A140-L144 WeakPolarHBondContact O-CB 3.37Å; A140-L144 PolarHBondContact O-N 3.23Å; L141-L144 WeakPolarHBondContact O-CB 3.31Å; L141-L144 PolarHBondContact O-N 3.17Å; L141-L144 VanDerWaalsContact O-N 3.17Å; F142-L144 VanDerWaalsContact C-N 3.31Å; F142-L144 PolarHBondContact O-N 3.5Å; L144-A146 VanDerWaalsContact C-N 3.34Å; L144-F147 PolarHBondContact O-N 2.94Å; L144-Y148 PolarHBondContact O-N 3.24Å; L144-C161 HydrophobicContact CB-CB 4.2Å; L144-C161 HydrophobicContact CD1-CB 4.31Å; L144-M162 HydrophobicContact CD1-CB 4.4Å; L144-M162 HydrophobicContact CD1-CG 3.35Å; L144-M162 HydrophobicContact CD1-SD 3.17Å; L144-M162 WeakPolarHBondContact CD1-SD 3.46Å; L144-M162 HydrophobicContact CG-SD 4.49Å; L144-F205 HydrophobicContact CD1-CZ 4.27Å; L144-F205 HydrophobicContact CD2-CZ 4.34Å; L144-M213 HydrophobicContact CD1-CE 4.05Å; L144-M213 HydrophobicContact CD2-CE 3.43Å; L144-M213 VanDerWaalsContact CD2-CE 3.43Å; L144-M213 HydrophobicContact CD2-SD 4.3Å; L144-M213 HydrophobicContact CG-CE 3.5Å; L144-M213 VanDerWaalsContact CG-CE 3.5Å
145	L	90	Very high	88.8	Confident	16 Å²	16	55.8 Å²	55.8	8%	0.084	32%	0.32	C	S	.	.	H	α-helix	trans	-61.7	-42.8	174.2	-73	174.7	0	0	0	111.7	V98 L102 L141 F142 F147 Y148 M149	V98-L145 HydrophobicContact CB-CD2 4.13Å; V98-L145 HydrophobicContact CG1-CD2 3.55Å; V98-L145 WeakPolarHBondContact O-CD2 3.24Å; L102-L145 HydrophobicContact CD1-CD1 4.09Å; L102-L145 HydrophobicContact CD2-CD1 3.51Å; L102-L145 HydrophobicContact CG-CD1 3.62Å; L141-L145 HydrophobicContact CD2-CD1 3.43Å; L141-L145 VanDerWaalsContact CD2-CD1 3.43Å; L141-L145 HydrophobicContact CD2-CG 3.95Å; L141-L145 WeakPolarHBondContact O-CG 3.28Å; L141-L145 PolarHBondContact O-N 3.47Å; F142-L145 PolarHBondContact O-N 3.24Å; L145-F147 VanDerWaalsContact C-N 3.34Å; L145-F147 PolarHBondContact O-N 3.32Å; L145-Y148 PolarHBondContact O-N 2.91Å; L145-M149 VanDerWaalsContact O-CG 3.27Å; L145-M149 WeakPolarHBondContact O-CG 3.44Å; L145-M149 PolarHBondContact O-N 3.32Å
146	A	90.6	Very high	88.8	Confident	49 Å²	49	54.6 Å²	54.6	41%	0.405	32%	0.323	S	S	.	.	H	α-helix	trans	-58.3	-47.4	176.2	0	0	0	0	0	111.1	F142 F143 L144 Y148 M149 T150	F142-A146 WeakPolarHBondContact O-CB 3.43Å; F142-A146 PolarHBondContact O-N 3.42Å; F143-A146 WeakPolarHBondContact O-CB 3.17Å; F143-A146 PolarHBondContact O-N 2.95Å; L144-A146 VanDerWaalsContact C-N 3.34Å; A146-Y148 VanDerWaalsContact C-N 3.35Å; A146-Y148 PolarHBondContact O-N 3.04Å; A146-M149 PolarHBondContact O-N 3.45Å; A146-T150 WeakPolarHBondContact O-CG2 3.25Å; A146-T150 PolarHBondContact O-N 2.98Å; A146-T150 PolarHBondContact O-OG1 3.38Å
147	F	89.4	Confident	88.9	Confident	46 Å²	46	55.4 Å²	55.4	20%	0.202	33%	0.33	C	S	.	.	H	α-helix	trans	-64.4	-36.5	177.6	-63.3	-39.4	0	0	0	113.4	F143 L144 L145 G151 S152 L157 V158	F143-F147 HydrophobicContact CB-CE2 4.22Å; F143-F147 WeakPolarHBondContact O-CD2 3.39Å; F143-F147 VanDerWaalsContact O-CG 3.31Å; F143-F147 WeakPolarHBondContact O-CG 3.42Å; F143-F147 PolarHBondContact O-N 3.38Å; L144-F147 PolarHBondContact O-N 2.94Å; L145-F147 VanDerWaalsContact C-N 3.34Å; L145-F147 PolarHBondContact O-N 3.32Å; F147-G151 WeakPolarHBondContact O-CA 3.39Å; F147-G151 PolarHBondContact O-N 3.09Å; F147-S152 VanDerWaalsContact CD1-O 3.25Å; F147-S152 WeakPolarHBondContact CD1-O 3.45Å; F147-S152 PolarHBondContact O-N 2.91Å; F147-L157 HydrophobicContact CE2-CB 4.19Å; F147-L157 HydrophobicContact CZ-CB 4.47Å; F147-L157 HydrophobicContact CZ-CD1 4.4Å; F147-V158 HydrophobicContact CB-CG2 4.24Å; F147-V158 HydrophobicContact CD2-CG2 4.23Å
148	Y	85.9	Confident	88.9	Confident	105 Å²	105	56 Å²	56	41%	0.412	33%	0.333	S	S	.	.	H	α-helix	trans	-64.5	-47.8	175.5	-177.7	-101.9	0	0	0	111.4	V98 L144 L145 A146 G151 V212 M213	V98-Y148 HydrophobicContact CB-CD1 4.07Å; V98-Y148 HydrophobicContact CB-CE1 4.05Å; V98-Y148 HydrophobicContact CG1-CD1 4.36Å; V98-Y148 HydrophobicContact CG1-CG 4.42Å; V98-Y148 HydrophobicContact CG2-CD1 3.88Å; V98-Y148 HydrophobicContact CG2-CD2 4.31Å; V98-Y148 HydrophobicContact CG2-CE1 3.48Å; V98-Y148 VanDerWaalsContact CG2-CE1 3.48Å; V98-Y148 HydrophobicContact CG2-CE2 3.94Å; V98-Y148 HydrophobicContact CG2-CG 4.28Å; L144-Y148 PolarHBondContact O-N 3.24Å; L145-Y148 PolarHBondContact O-N 2.91Å; A146-Y148 VanDerWaalsContact C-N 3.35Å; A146-Y148 PolarHBondContact O-N 3.04Å; Y148-G151 PolarHBondContact O-N 3.46Å; Y148-V212 HydrophobicContact CE2-CG1 4.08Å; Y148-M213 HydrophobicContact CD2-CE 4.33Å; Y148-M213 HydrophobicContact CD2-SD 3.54Å; Y148-M213 VanDerWaalsContact CD2-SD 3.54Å; Y148-M213 HydrophobicContact CE2-SD 4.28Å; Y148-M213 HydrophobicContact CG-SD 4.29Å
149	M	86.5	Confident	88.9	Confident	121 Å²	121	55.7 Å²	55.7	60%	0.596	33%	0.332	S	S	*	.	H	α-helix	trans	-69.6	-37.3	-177.4	-65.7	-60.5	-121.2	0	0	112.9	V99 L145 A146 G151	V99-M149 HydrophobicContact CG2-CE 3.72Å; L145-M149 VanDerWaalsContact O-CG 3.27Å; L145-M149 WeakPolarHBondContact O-CG 3.44Å; L145-M149 PolarHBondContact O-N 3.32Å; A146-M149 PolarHBondContact O-N 3.45Å; M149-G151 VanDerWaalsContact C-N 3.34Å
150	T	87.4	Confident	88.9	Confident	91 Å²	91	55.3 Å²	55.3	56%	0.558	33%	0.327	S	S	*	.	H	α-helix	trans	-81.6	-16.1	177.4	62.5	0	0	0	0	112.9	A146 S152	A146-T150 WeakPolarHBondContact O-CG2 3.25Å; A146-T150 PolarHBondContact O-N 2.98Å; A146-T150 PolarHBondContact O-OG1 3.38Å; T150-S152 WeakPolarHBondContact CB-OG 3.25Å; T150-S152 PolarHBondContact O-N 3.41Å; T150-S152 PolarHBondContact OG1-N 3.08Å; T150-S152 PolarHBondContact OG1-OG 3.17Å
151	G	83.2	Confident	88.9	Confident	68 Å²	68	55.6 Å²	55.6	70%	0.701	33%	0.328	S	S	*	.	S	Bend	trans	63.1	13.9	-168.7	0	0	0	0	0	113.5	F147 Y148 M149	F147-G151 WeakPolarHBondContact O-CA 3.39Å; F147-G151 PolarHBondContact O-N 3.09Å; Y148-G151 PolarHBondContact O-N 3.46Å; M149-G151 VanDerWaalsContact C-N 3.34Å
152	S	81.1	Confident	88.9	Confident	78 Å²	78	55.5 Å²	55.5	55%	0.545	33%	0.328	S	S	.	.			trans	-119	71.8	-170.2	76	0	0	0	0	111.2	F147 T150	F147-S152 VanDerWaalsContact CD1-O 3.25Å; F147-S152 WeakPolarHBondContact CD1-O 3.45Å; F147-S152 PolarHBondContact O-N 2.91Å; T150-S152 WeakPolarHBondContact CB-OG 3.25Å; T150-S152 PolarHBondContact O-N 3.41Å; T150-S152 PolarHBondContact OG1-N 3.08Å; T150-S152 PolarHBondContact OG1-OG 3.17Å
153	G	80.8	Confident	88.9	Confident	32 Å²	32	52.2 Å²	52.2	33%	0.33	32%	0.315	S	S	.	.			trans	-132.7	133.2	172.4	0	0	0	0	0	110.3
154	S	86.5	Confident	89	Confident	64 Å²	64	48.7 Å²	48.7	45%	0.448	30%	0.301	S	S	.	.			trans	-65.4	140.9	166.5	66.7	0	0	0	0	108.6	C156 L157 V158	S154-C156 PolarHBondContact O-N 3.46Å; S154-C156 VanDerWaalsContact O-N 3.08Å; S154-L157 PolarHBondContact O-N 3.12Å; S154-L157 WeakPolarHBondContact OG-CB 3.34Å; S154-L157 WeakPolarHBondContact OG-CD1 3.35Å; S154-L157 VanDerWaalsContact OG-CG 3.25Å; S154-L157 WeakPolarHBondContact OG-CG 3.34Å; S154-L157 PolarHBondContact OG-N 2.96Å; S154-V158 PolarHBondContact O-N 2.92Å
155	S	87.3	Confident	89.1	Confident	49 Å²	49	48.7 Å²	48.7	34%	0.343	30%	0.301	S	S	.	.	H	α-helix	trans	-54.3	-34.2	-178.6	56.9	0	0	0	0	112	S159 E217 C219	S155-S159 WeakPolarHBondContact O-CB 3.16Å; S155-S159 PolarHBondContact O-N 2.87Å; S155-S159 PolarHBondContact O-OG 2.95Å; S155-E217 VanDerWaalsContact CB-O 3.23Å; S155-E217 WeakPolarHBondContact CB-O 3.26Å; S155-E217 PolarHBondContact OG-O 3.31Å; S155-C219 PolarHBondContact OG-SG 3.46Å; S155-C219 VanDerWaalsContact OG-SG 3.4Å
156	C	89.6	Confident	89.3	Confident	53 Å²	53	48.3 Å²	48.3	36%	0.358	30%	0.299	S	S	.	.	H	α-helix	trans	-66.7	-44.8	176.5	-65.9	0	0	0	0	112.4	S154 S159 L160 C219 L222	S154-C156 PolarHBondContact O-N 3.46Å; S154-C156 VanDerWaalsContact O-N 3.08Å; C156-S159 WeakPolarHBondContact CA-OG 3.22Å; C156-S159 PolarHBondContact O-N 3.16Å; C156-S159 PolarHBondContact O-OG 3.39Å; C156-L160 WeakPolarHBondContact O-CB 3.2Å; C156-L160 PolarHBondContact O-N 3.29Å; C156-C219 WeakPolarHBondContact CA-SG 3.33Å; C156-C219 HydrophobicContact CB-CB 4.14Å; C156-C219 WeakPolarHBondContact CB-SG 3.34Å; C156-C219 PolarHBondContact N-SG 2.92Å; C156-C219 WeakPolarHBondContact SG-CB 3.37Å; C156-C219 CovalentContact SG-SG 2.04Å; C156-C219 PolarHBondContact SG-SG 3.02Å; C156-L222 HydrophobicContact CB-CD1 3.76Å; C156-L222 WeakPolarHBondContact O-CD1 3.18Å
157	L	91.1	Very high	89.3	Confident	87 Å²	87	46.2 Å²	46.2	46%	0.455	28%	0.282	S	S	.	.	H	α-helix	trans	-64.3	-43	177.4	-75.2	173	0	0	0	111.4	F147 S154 S159 L160 C161	F147-L157 HydrophobicContact CE2-CB 4.19Å; F147-L157 HydrophobicContact CZ-CB 4.47Å; F147-L157 HydrophobicContact CZ-CD1 4.4Å; S154-L157 PolarHBondContact O-N 3.12Å; S154-L157 WeakPolarHBondContact OG-CB 3.34Å; S154-L157 WeakPolarHBondContact OG-CD1 3.35Å; S154-L157 VanDerWaalsContact OG-CG 3.25Å; S154-L157 WeakPolarHBondContact OG-CG 3.34Å; S154-L157 PolarHBondContact OG-N 2.96Å; L157-S159 VanDerWaalsContact C-N 3.34Å; L157-S159 PolarHBondContact O-N 3.35Å; L157-L160 PolarHBondContact O-N 2.93Å; L157-C161 PolarHBondContact O-N 2.82Å; L157-C161 PolarHBondContact O-SG 3.21Å; L157-C161 VanDerWaalsContact O-SG 3.38Å
158	V	91.6	Very high	89.4	Confident	12 Å²	12	44 Å²	44	7%	0.073	27%	0.272	C	S	.	.	H	α-helix	trans	-59.5	-46.6	175.9	176.8	0	0	0	0	110.6	F147 S154 L160 C161 M162 M213	F147-V158 HydrophobicContact CB-CG2 4.24Å; F147-V158 HydrophobicContact CD2-CG2 4.23Å; S154-V158 PolarHBondContact O-N 2.92Å; V158-L160 VanDerWaalsContact C-N 3.33Å; V158-L160 PolarHBondContact O-N 2.04Å; V158-C161 PolarHBondContact O-N 2.98Å; V158-M162 WeakPolarHBondContact O-CG 3.46Å; V158-M162 PolarHBondContact O-N 3.34Å; V158-M213 HydrophobicContact CG1-CB 3.93Å; V158-M213 HydrophobicContact CG1-CE 3.71Å
159	S	91.6	Very high	89.7	Confident	0 Å²	0	39.1 Å²	39.1	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-65.7	-33.3	178.3	70	0	0	0	0	113.5	S155 C156 L157 L163 L222	S155-S159 WeakPolarHBondContact O-CB 3.16Å; S155-S159 PolarHBondContact O-N 2.87Å; S155-S159 PolarHBondContact O-OG 2.95Å; C156-S159 WeakPolarHBondContact CA-OG 3.22Å; C156-S159 PolarHBondContact O-N 3.16Å; C156-S159 PolarHBondContact O-OG 3.39Å; L157-S159 VanDerWaalsContact C-N 3.34Å; L157-S159 PolarHBondContact O-N 3.35Å; S159-L163 WeakPolarHBondContact O-CB 3.36Å; S159-L163 PolarHBondContact O-N 3.17Å; S159-L222 WeakPolarHBondContact OG-CD1 3.41Å
160	L	93	Very high	89.9	Confident	72 Å²	72	33.4 Å²	33.4	38%	0.377	23%	0.225	S	C	.	.	H	α-helix	trans	-68.7	-44.4	175	-175.8	146.3	0	0	0	111	C156 L157 V158 L163 L164 L222	C156-L160 WeakPolarHBondContact O-CB 3.2Å; C156-L160 PolarHBondContact O-N 3.29Å; L157-L160 PolarHBondContact O-N 2.93Å; V158-L160 VanDerWaalsContact C-N 3.33Å; V158-L160 PolarHBondContact O-N 2.04Å; L160-L163 PolarHBondContact O-N 2.75Å; L160-L164 HydrophobicContact CD2-CD1 3.78Å; L160-L164 HydrophobicContact CD2-CG 4.3Å; L160-L164 WeakPolarHBondContact O-CG 3.16Å; L160-L164 PolarHBondContact O-N 3.08Å; L160-L222 HydrophobicContact CB-CD1 4.37Å; L160-L222 HydrophobicContact CD1-CD2 4.35Å
161	C	93.3	Very high	89.9	Confident	9 Å²	9	29 Å²	29	6%	0.061	20%	0.198	C	C	.	.	H	α-helix	trans	-60.5	-46	174.7	-69.8	0	0	0	0	111.4	A140 L144 L157 V158 L163 L164 V165	A140-C161 HydrophobicContact CB-CB 4.44Å; L144-C161 HydrophobicContact CB-CB 4.2Å; L144-C161 HydrophobicContact CD1-CB 4.31Å; L157-C161 PolarHBondContact O-N 2.82Å; L157-C161 PolarHBondContact O-SG 3.21Å; L157-C161 VanDerWaalsContact O-SG 3.38Å; V158-C161 PolarHBondContact O-N 2.98Å; C161-L163 VanDerWaalsContact C-N 3.34Å; C161-L163 PolarHBondContact O-N 3.44Å; C161-L164 PolarHBondContact O-N 2.81Å; C161-V165 WeakPolarHBondContact O-CG2 3.13Å; C161-V165 PolarHBondContact O-N 3.41Å
162	M	92.3	Very high	90.1	Very high	1 Å²	1	26.3 Å²	26.3	1%	0.005	17%	0.167	C	C	.	.	H	α-helix	trans	-56.6	-47.2	174.3	-75.5	-69	-67	0	0	111.9	L144 V158 L164 V165 V166 F205 Y206 C215	L144-M162 HydrophobicContact CD1-CB 4.4Å; L144-M162 HydrophobicContact CD1-CG 3.35Å; L144-M162 HydrophobicContact CD1-SD 3.17Å; L144-M162 WeakPolarHBondContact CD1-SD 3.46Å; L144-M162 HydrophobicContact CG-SD 4.49Å; V158-M162 WeakPolarHBondContact O-CG 3.46Å; V158-M162 PolarHBondContact O-N 3.34Å; M162-L164 VanDerWaalsContact C-N 3.31Å; M162-L164 PolarHBondContact O-N 3.49Å; M162-V165 PolarHBondContact O-N 3.22Å; M162-V166 WeakPolarHBondContact O-CG2 3.31Å; M162-V166 PolarHBondContact O-N 3.43Å; M162-F205 HydrophobicContact CE-CD1 3.91Å; M162-F205 HydrophobicContact CE-CE1 3.49Å; M162-F205 VanDerWaalsContact CE-CE1 3.49Å; M162-F205 HydrophobicContact CE-CZ 4.08Å; M162-F205 HydrophobicContact SD-CD1 4.19Å; M162-F205 HydrophobicContact SD-CE1 3.18Å; M162-F205 WeakPolarHBondContact SD-CE1 3.47Å; M162-F205 HydrophobicContact SD-CZ 3.43Å; M162-F205 WeakPolarHBondContact SD-CZ 3.34Å; M162-Y206 HydrophobicContact CE-CD2 4.43Å; M162-C215 VanDerWaalsContact CG-SG 3.6Å
163	L	92.9	Very high	90.1	Very high	30 Å²	30	24.8 Å²	24.8	16%	0.157	15%	0.151	C	C	.	.	H	α-helix	trans	-60.3	-40.4	178.5	-178.2	141.8	0	0	0	112	S159 L160 C161 V166 A167 F225	S159-L163 WeakPolarHBondContact O-CB 3.36Å; S159-L163 PolarHBondContact O-N 3.17Å; L160-L163 PolarHBondContact O-N 2.75Å; C161-L163 VanDerWaalsContact C-N 3.34Å; C161-L163 PolarHBondContact O-N 3.44Å; L163-V166 PolarHBondContact O-N 3.06Å; L163-A167 WeakPolarHBondContact O-CB 3.09Å; L163-A167 PolarHBondContact O-N 2.82Å; L163-F225 HydrophobicContact CD1-CD1 4.36Å; L163-F225 HydrophobicContact CD2-CE1 4.44Å
164	L	93.3	Very high	90.3	Very high	39 Å²	39	25.3 Å²	25.3	20%	0.204	15%	0.149	C	C	.	.	H	α-helix	trans	-66.3	-42	177.5	-71.7	-179.2	0	0	0	112.5	F136 A140 L160 C161 M162 A167 T168 F175	F136-L164 HydrophobicContact CE1-CD1 4.32Å; F136-L164 HydrophobicContact CE1-CD2 3.95Å; A140-L164 HydrophobicContact CB-CB 3.73Å; A140-L164 HydrophobicContact CB-CD1 4.17Å; L160-L164 HydrophobicContact CD2-CD1 3.78Å; L160-L164 HydrophobicContact CD2-CG 4.3Å; L160-L164 WeakPolarHBondContact O-CG 3.16Å; L160-L164 PolarHBondContact O-N 3.08Å; C161-L164 PolarHBondContact O-N 2.81Å; M162-L164 VanDerWaalsContact C-N 3.31Å; M162-L164 PolarHBondContact O-N 3.49Å; L164-A167 PolarHBondContact O-N 3.14Å; L164-T168 WeakPolarHBondContact O-CB 3.45Å; L164-T168 VanDerWaalsContact O-CG2 3.27Å; L164-T168 WeakPolarHBondContact O-CG2 3.2Å; L164-T168 PolarHBondContact O-N 2.92Å; L164-T168 PolarHBondContact O-OG1 3.33Å; L164-F175 HydrophobicContact CD2-CE2 4.34Å
165	V	93.6	Very high	90.2	Very high	0 Å²	0	23.7 Å²	23.7	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-60.8	-48.7	175.4	176.3	0	0	0	0	110.3	L104 A140 L141 C161 M162 T168 K169 F205	L104-V165 HydrophobicContact CD1-CG1 4.4Å; A140-V165 HydrophobicContact CB-CG2 4.03Å; L141-V165 HydrophobicContact CB-CG2 3.91Å; C161-V165 WeakPolarHBondContact O-CG2 3.13Å; C161-V165 PolarHBondContact O-N 3.41Å; M162-V165 PolarHBondContact O-N 3.22Å; V165-T168 PolarHBondContact O-OG1 3.16Å; V165-T168 VanDerWaalsContact O-OG1 3.04Å; V165-K169 WeakPolarHBondContact O-CG 3.25Å; V165-K169 PolarHBondContact O-N 3.28Å; V165-F205 HydrophobicContact CB-CD1 4.28Å; V165-F205 HydrophobicContact CB-CE1 3.87Å; V165-F205 HydrophobicContact CG1-CD1 3.64Å; V165-F205 HydrophobicContact CG1-CE1 3.58Å; V165-F205 HydrophobicContact CG1-CG 4.31Å; V165-F205 HydrophobicContact CG1-CZ 4.25Å; V165-F205 HydrophobicContact CG2-CE1 4.31Å
166	V	93.4	Very high	89.9	Confident	8 Å²	8	22.9 Å²	22.9	5%	0.048	13%	0.128	C	C	.	.	H	α-helix	trans	-62.9	-51.6	178.4	177	0	0	0	0	110.1	M162 L163 T168 K169 S170 L172 M203 F205 Y206	M162-V166 WeakPolarHBondContact O-CG2 3.31Å; M162-V166 PolarHBondContact O-N 3.43Å; L163-V166 PolarHBondContact O-N 3.06Å; V166-T168 VanDerWaalsContact C-N 3.3Å; V166-T168 PolarHBondContact O-N 2.96Å; V166-K169 PolarHBondContact O-N 2.89Å; V166-S170 WeakPolarHBondContact O-CA 3.2Å; V166-S170 VanDerWaalsContact O-CB 3.29Å; V166-S170 WeakPolarHBondContact O-CB 3.28Å; V166-S170 PolarHBondContact O-N 3Å; V166-S170 PolarHBondContact O-OG 3.25Å; V166-L172 HydrophobicContact CG1-CD1 4.15Å; V166-M203 HydrophobicContact CG1-SD 4.11Å; V166-F205 HydrophobicContact CG2-CD1 4.49Å; V166-Y206 HydrophobicContact CG2-CD2 4.07Å; V166-Y206 HydrophobicContact CG2-CG 4.46Å
167	A	91.7	Very high	89.5	Confident	5 Å²	5	22.1 Å²	22.1	4%	0.041	12%	0.123	C	C	.	.	H	α-helix	trans	-60.3	-37.8	-174.4	0	0	0	0	0	113.5	L163 L164 A171 L172 F175	L163-A167 WeakPolarHBondContact O-CB 3.09Å; L163-A167 PolarHBondContact O-N 2.82Å; L164-A167 PolarHBondContact O-N 3.14Å; A167-A171 PolarHBondContact O-N 3.48Å; A167-L172 HydrophobicContact CB-CB 3.97Å; A167-L172 HydrophobicContact CB-CD1 4.29Å; A167-L172 PolarHBondContact O-N 3.31Å; A167-F175 HydrophobicContact CB-CD2 4.12Å
168	T	91.4	Very high	89.2	Confident	1 Å²	1	18.1 Å²	18.1	1%	0.006	10%	0.102	C	C	.	.	H	α-helix	trans	-73.7	-47.5	179	52.2	0	0	0	0	112.2	F136 G137 L164 V165 V166 F175 W178	F136-T168 HydrophobicContact CB-CG2 4.38Å; F136-T168 HydrophobicContact CD1-CG2 3.91Å; G137-T168 WeakPolarHBondContact CA-OG1 3.3Å; L164-T168 WeakPolarHBondContact O-CB 3.45Å; L164-T168 VanDerWaalsContact O-CG2 3.27Å; L164-T168 WeakPolarHBondContact O-CG2 3.2Å; L164-T168 PolarHBondContact O-N 2.92Å; L164-T168 PolarHBondContact O-OG1 3.33Å; V165-T168 PolarHBondContact O-OG1 3.16Å; V165-T168 VanDerWaalsContact O-OG1 3.04Å; V166-T168 VanDerWaalsContact C-N 3.3Å; V166-T168 PolarHBondContact O-N 2.96Å; T168-F175 HydrophobicContact CG2-CD1 4.32Å; T168-F175 HydrophobicContact CG2-CD2 3.85Å; T168-F175 HydrophobicContact CG2-CE2 4.06Å; T168-F175 HydrophobicContact CG2-CG 3.99Å; T168-F175 HydrophobicContact CG2-CZ 4.39Å; T168-W178 PolarHBondContact O-NE1 3.04Å
169	K	91.2	Very high	89	Confident	2 Å²	2	17.6 Å²	17.6	1%	0.009	10%	0.099	C	C	.	.	H	α-helix	trans	-74.5	-32.6	-179.5	-61.1	-71.2	-179.2	177.2	0	112.6	L104 D138 V165 V166 W178 L198 V199	L104-K169 PolarHBondContact O-NZ 3.48Å; D138-K169 WeakPolarHBondContact OD1-CE 3.46Å; D138-K169 IonicContact OD1-NZ 2.75Å; D138-K169 PolarHBondContact OD1-NZ 3.44Å; D138-K169 IonicContact OD2-NZ 3.72Å; V165-K169 WeakPolarHBondContact O-CG 3.25Å; V165-K169 PolarHBondContact O-N 3.28Å; V166-K169 PolarHBondContact O-N 2.89Å; K169-W178 WeakPolarHBondContact O-CZ2 3.26Å; K169-L198 HydrophobicContact CD-CD2 4.49Å; K169-L198 VanDerWaalsContact O-CD2 3.25Å; K169-L198 WeakPolarHBondContact O-CD2 3.5Å; K169-V199 WeakPolarHBondContact O-CA 3.3Å
170	S	91.3	Very high	88.7	Confident	0 Å²	0	19 Å²	19	0%	0	11%	0.106	C	C	.	.	T	Hydrogen-bonded Turn	trans	-97.5	7.3	-176.8	79.8	0	0	0	0	115	V166 L172	V166-S170 WeakPolarHBondContact O-CA 3.2Å; V166-S170 VanDerWaalsContact O-CB 3.29Å; V166-S170 WeakPolarHBondContact O-CB 3.28Å; V166-S170 PolarHBondContact O-N 3Å; V166-S170 PolarHBondContact O-OG 3.25Å; S170-L172 PolarHBondContact O-N 3.48Å; S170-L172 WeakPolarHBondContact OG-CG 3.49Å
171	A	87.2	Confident	88.3	Confident	0 Å²	0	17.3 Å²	17.3	0%	0	10%	0.096	C	C	.	.	T	Hydrogen-bonded Turn	trans	58.9	41.9	176.5	0	0	0	0	0	114.2	A167 S176 W178 L179	A167-A171 PolarHBondContact O-N 3.48Å; A171-S176 WeakPolarHBondContact O-CB 3.39Å; A171-W178 HydrophobicContact CB-CZ2 3.8Å; A171-L179 HydrophobicContact CB-CB 4Å; A171-L179 HydrophobicContact CB-CD2 4.47Å
172	L	88.9	Confident	88	Confident	10 Å²	10	17 Å²	17	5%	0.052	9%	0.094	C	C	.	.			trans	-78	157.9	172	-59.8	174.8	0	0	0	111	V166 A167 S170 P174 F175 S176 T233 S260 V263	V166-L172 HydrophobicContact CG1-CD1 4.15Å; A167-L172 HydrophobicContact CB-CB 3.97Å; A167-L172 HydrophobicContact CB-CD1 4.29Å; A167-L172 PolarHBondContact O-N 3.31Å; S170-L172 PolarHBondContact O-N 3.48Å; S170-L172 WeakPolarHBondContact OG-CG 3.49Å; L172-P174 CarbonylContact O-C 3.59Å; L172-F175 CarbonylContact O-C 3.6Å; L172-F175 VanDerWaalsContact O-C 3.26Å; L172-F175 VanDerWaalsContact O-CA 3.25Å; L172-F175 WeakPolarHBondContact O-CA 3.45Å; L172-F175 PolarHBondContact O-N 2.93Å; L172-S176 PolarHBondContact O-N 3.27Å; L172-T233 HydrophobicContact CB-CG2 4.16Å; L172-T233 HydrophobicContact CD2-CG2 4.13Å; L172-S260 WeakPolarHBondContact CD2-OG 3.3Å; L172-V263 HydrophobicContact CD1-CG1 4.29Å; L172-V263 HydrophobicContact CD1-CG2 4.07Å; L172-V263 HydrophobicContact CD2-CG2 4.13Å
173	F	81.1	Confident	87.9	Confident	47 Å²	47	17.1 Å²	17.1	21%	0.206	10%	0.095	C	C	.	.	T	Hydrogen-bonded Turn	trans	-67.3	129.1	178	179.9	-96.3	0	0	0	108.2	T233 I236	F173-T233 HydrophobicContact CB-CG2 3.34Å; F173-I236 HydrophobicContact CD2-CD1 4.15Å; F173-I236 HydrophobicContact CE2-CD1 4.27Å
174	P	84	Confident	87.5	Confident	43 Å²	43	18.7 Å²	18.7	28%	0.279	10%	0.099	S	C	.	.	T	Hydrogen-bonded Turn	cis	-90.8	-7.3	13.1	34.8	-36.4	0	0	0	116.4	L172 S176 V482	L172-P174 CarbonylContact O-C 3.59Å; P174-S176 PolarHBondContact O-N 2.68Å; P174-V482 HydrophobicContact CB-CG1 4.5Å
175	F	83.8	Confident	87.3	Confident	29 Å²	29	16.9 Å²	16.9	13%	0.127	9%	0.089	C	C	.	.	T	Hydrogen-bonded Turn	trans	-80.5	34	-175.7	-54.5	-70.2	0	0	0	114.9	F136 L164 A167 T168 L172 W178	F136-F175 AromaticContact CD1-CE1 3.95Å; F136-F175 HydrophobicContact CD1-CE1 3.95Å; F136-F175 HydrophobicContact CD1-CE2 4.28Å; F136-F175 AromaticContact CD1-CZ 3.57Å; F136-F175 HydrophobicContact CD1-CZ 3.57Å; F136-F175 HydrophobicContact CE1-CE1 4.23Å; F136-F175 HydrophobicContact CE1-CE2 4.2Å; F136-F175 AromaticContact CE1-CZ 3.49Å; F136-F175 HydrophobicContact CE1-CZ 3.49Å; F136-F175 VanDerWaalsContact CE1-CZ 3.49Å; F136-F175 HydrophobicContact CZ-CZ 4.41Å; L164-F175 HydrophobicContact CD2-CE2 4.34Å; A167-F175 HydrophobicContact CB-CD2 4.12Å; T168-F175 HydrophobicContact CG2-CD1 4.32Å; T168-F175 HydrophobicContact CG2-CD2 3.85Å; T168-F175 HydrophobicContact CG2-CE2 4.06Å; T168-F175 HydrophobicContact CG2-CG 3.99Å; T168-F175 HydrophobicContact CG2-CZ 4.39Å; L172-F175 CarbonylContact O-C 3.6Å; L172-F175 VanDerWaalsContact O-C 3.26Å; L172-F175 VanDerWaalsContact O-CA 3.25Å; L172-F175 WeakPolarHBondContact O-CA 3.45Å; L172-F175 PolarHBondContact O-N 2.93Å; F175-W178 PolarHBondContact O-NE1 3.04Å; F175-W178 VanDerWaalsContact O-NE1 3.09Å
176	S	82.3	Confident	87.2	Confident	32 Å²	32	16.9 Å²	16.9	22%	0.224	9%	0.089	C	C	.	.	T	Hydrogen-bonded Turn	trans	-84.5	-16	-179.6	62.3	0	0	0	0	114.3	A171 L172 P174 W178 L179	A171-S176 WeakPolarHBondContact O-CB 3.39Å; L172-S176 PolarHBondContact O-N 3.27Å; P174-S176 PolarHBondContact O-N 2.68Å; S176-W178 PolarHBondContact O-N 3.23Å; S176-L179 PolarHBondContact O-N 3.34Å
177	S	80.2	Confident	87.1	Confident	37 Å²	37	16.6 Å²	16.6	26%	0.259	9%	0.087	S	C	.	.	H	α-helix	trans	-64.5	-37.3	-172	57.3	0	0	0	0	113.9	L179 L180 E181	S177-L179 VanDerWaalsContact C-N 3.26Å; S177-L179 PolarHBondContact O-N 2.98Å; S177-L180 PolarHBondContact O-N 3.44Å; S177-L180 VanDerWaalsContact O-N 3.16Å; S177-E181 PolarHBondContact O-N 3.25Å
178	W	85.2	Confident	87	Confident	4 Å²	4	16.3 Å²	16.3	2%	0.015	9%	0.085	C	C	.	.	H	α-helix	trans	-63.2	-34.3	-175	74.5	-100.9	0	0	0	112.1	V129 T130 S133 T168 K169 A171 F175 S176 L180 E181 A182 L198 V199	V129-W178 HydrophobicContact CG1-CB 4.15Å; T130-W178 HydrophobicContact CG2-CB 3.99Å; T130-W178 HydrophobicContact CG2-CD2 4.5Å; T130-W178 HydrophobicContact CG2-CE3 3.77Å; T130-W178 WeakPolarHBondContact CG2-O 3.31Å; S133-W178 VanDerWaalsContact OG-CB 3.29Å; S133-W178 WeakPolarHBondContact OG-CB 3.42Å; S133-W178 VanDerWaalsContact OG-CG 3.28Å; T168-W178 PolarHBondContact O-NE1 3.04Å; K169-W178 WeakPolarHBondContact O-CZ2 3.26Å; A171-W178 HydrophobicContact CB-CZ2 3.8Å; F175-W178 PolarHBondContact O-NE1 3.04Å; F175-W178 VanDerWaalsContact O-NE1 3.09Å; S176-W178 PolarHBondContact O-N 3.23Å; W178-L180 VanDerWaalsContact C-N 3.32Å; W178-L180 PolarHBondContact O-N 3.01Å; W178-E181 PolarHBondContact O-N 3.42Å; W178-A182 WeakPolarHBondContact O-CB 3.32Å; W178-A182 PolarHBondContact O-N 3.32Å; W178-L198 HydrophobicContact CH2-CD1 4.09Å; W178-L198 HydrophobicContact CH2-CD2 3.27Å; W178-L198 HydrophobicContact CH2-CG 4.2Å; W178-L198 HydrophobicContact CZ2-CD2 3.8Å; W178-L198 HydrophobicContact CZ3-CD1 3.94Å; W178-L198 HydrophobicContact CZ3-CD2 3.98Å; W178-V199 HydrophobicContact CH2-CG2 3.98Å
179	L	86.5	Confident	87	Confident	1 Å²	1	16.4 Å²	16.4	1%	0.005	9%	0.086	C	C	.	.	H	α-helix	trans	-65	-37.6	178.8	-167.3	83.9	0	0	0	111.6	A171 S176 S177 A182 M183 H194 V199 A252 T255 C256	A171-L179 HydrophobicContact CB-CB 4Å; A171-L179 HydrophobicContact CB-CD2 4.47Å; S176-L179 PolarHBondContact O-N 3.34Å; S177-L179 VanDerWaalsContact C-N 3.26Å; S177-L179 PolarHBondContact O-N 2.98Å; L179-A182 PolarHBondContact O-N 3.42Å; L179-M183 HydrophobicContact CG-CE 4.47Å; L179-H194 HydrophobicContact CD1-CB 4.2Å; L179-V199 HydrophobicContact CD1-CG2 3.61Å; L179-A252 HydrophobicContact CD2-CB 4.02Å; L179-A252 WeakPolarHBondContact CD2-O 3.42Å; L179-A252 HydrophobicContact CG-CB 4.41Å; L179-T255 WeakPolarHBondContact CD2-OG1 3.39Å; L179-C256 WeakPolarHBondContact CD2-SG 3.44Å
180	L	86.6	Confident	87	Confident	29 Å²	29	16.3 Å²	16.3	15%	0.152	9%	0.085	C	C	.	.	H	α-helix	trans	-70.1	-39	178.5	-61.1	176.1	0	0	0	111.8	S177 W178 A182 M183 Y240 Q249 A252 L253	S177-L180 PolarHBondContact O-N 3.44Å; S177-L180 VanDerWaalsContact O-N 3.16Å; W178-L180 VanDerWaalsContact C-N 3.32Å; W178-L180 PolarHBondContact O-N 3.01Å; L180-A182 VanDerWaalsContact C-N 3.33Å; L180-M183 PolarHBondContact O-N 3.16Å; L180-Y240 HydrophobicContact CD1-CE1 4.03Å; L180-Q249 HydrophobicContact CD2-CB 4.41Å; L180-A252 HydrophobicContact CD2-CB 4.04Å; L180-L253 HydrophobicContact CD1-CD2 4.33Å; L180-L253 HydrophobicContact CD2-CD1 4.4Å; L180-L253 HydrophobicContact CD2-CD2 3.78Å; L180-L253 HydrophobicContact CD2-CG 3.78Å
181	E	85.1	Confident	87	Confident	37 Å²	37	16.3 Å²	16.3	17%	0.173	9%	0.085	C	C	.	.	H	α-helix	trans	-69.5	-31.5	177.3	-74	-69	134.6	0	0	112.3	S177 W178 M183 R184	S177-E181 PolarHBondContact O-N 3.25Å; W178-E181 PolarHBondContact O-N 3.42Å; E181-M183 PolarHBondContact O-N 3.45Å; E181-R184 VanDerWaalsContact CD-NH2 3.29Å; E181-R184 PolarHBondContact O-N 3.33Å; E181-R184 IonicContact OE1-CZ 3.85Å; E181-R184 IonicContact OE1-NH2 2.97Å; E181-R184 PolarHBondContact OE1-NH2 2.88Å; E181-R184 IonicContact OE2-CZ 3Å; E181-R184 IonicContact OE2-NH1 2.65Å; E181-R184 PolarHBondContact OE2-NH1 3.48Å; E181-R184 IonicContact OE2-NH2 2.87Å; E181-R184 PolarHBondContact OE2-NH2 3.41Å
182	A	86.7	Confident	87.2	Confident	1 Å²	1	16.4 Å²	16.4	1%	0.008	9%	0.086	C	C	.	.	H	α-helix	trans	-66.1	-22.5	176.9	0	0	0	0	0	113.7	M115 T130 W178 L179 L180 R184 A185 H194	M115-A182 HydrophobicContact SD-CB 3.58Å; M115-A182 VanDerWaalsContact SD-CB 3.58Å; T130-A182 HydrophobicContact CG2-CB 3.91Å; W178-A182 WeakPolarHBondContact O-CB 3.32Å; W178-A182 PolarHBondContact O-N 3.32Å; L179-A182 PolarHBondContact O-N 3.42Å; L180-A182 VanDerWaalsContact C-N 3.33Å; A182-R184 PolarHBondContact O-N 2.75Å; A182-A185 WeakPolarHBondContact O-CB 3.31Å; A182-A185 PolarHBondContact O-N 3.03Å; A182-A185 VanDerWaalsContact O-N 3.08Å; A182-H194 WeakPolarHBondContact CB-CE1 2.95Å; A182-H194 VanDerWaalsContact CB-NE2 3.3Å; A182-H194 WeakPolarHBondContact CB-NE2 3.2Å
183	M	88.8	Confident	87.1	Confident	4 Å²	4	16.1 Å²	16.1	2%	0.02	8%	0.084	C	C	.	.	T	Hydrogen-bonded Turn	trans	-67.1	0.2	179.8	-66.9	-61.6	157.9	0	0	114.2	L179 L180 E181 A185 H194 K248 Q249 A252 F289	L179-M183 HydrophobicContact CG-CE 4.47Å; L180-M183 PolarHBondContact O-N 3.16Å; E181-M183 PolarHBondContact O-N 3.45Å; M183-A185 VanDerWaalsContact C-N 3.33Å; M183-H194 HydrophobicContact CE-CB 3.71Å; M183-H194 WeakPolarHBondContact CE-CD2 3.46Å; M183-K248 HydrophobicContact CB-CB 4.04Å; M183-K248 HydrophobicContact CG-CB 4.37Å; M183-K248 WeakPolarHBondContact O-CE 3.34Å; M183-K248 PolarHBondContact O-NZ 3.38Å; M183-K248 HydrophobicContact SD-CB 4.29Å; M183-Q249 HydrophobicContact CB-CG 4.47Å; M183-A252 HydrophobicContact CE-CB 3.43Å; M183-A252 VanDerWaalsContact CE-CB 3.43Å; M183-A252 HydrophobicContact CG-CB 3.8Å; M183-A252 HydrophobicContact SD-CB 4.17Å; M183-F289 HydrophobicContact CE-CE1 4.09Å; M183-F289 HydrophobicContact CE-CZ 3.69Å; M183-F289 HydrophobicContact SD-CE1 3.83Å; M183-F289 HydrophobicContact SD-CZ 4.08Å
184	R	85.6	Confident	87	Confident	64 Å²	64	13.9 Å²	13.9	24%	0.242	8%	0.075	C	C	.	.	T	Hydrogen-bonded Turn	trans	-75.2	-21.4	169.5	-65.9	-177.1	179.6	135.4	20.6	113.3	S122 E181 A182	S122-R184 VanDerWaalsContact C-CD 3.5Å; S122-R184 WeakPolarHBondContact O-CD 3.37Å; S122-R184 PolarHBondContact O-NH1 2.65Å; E181-R184 VanDerWaalsContact CD-NH2 3.29Å; E181-R184 PolarHBondContact O-N 3.33Å; E181-R184 IonicContact OE1-CZ 3.85Å; E181-R184 IonicContact OE1-NH2 2.97Å; E181-R184 PolarHBondContact OE1-NH2 2.88Å; E181-R184 IonicContact OE2-CZ 3Å; E181-R184 IonicContact OE2-NH1 2.65Å; E181-R184 PolarHBondContact OE2-NH1 3.48Å; E181-R184 IonicContact OE2-NH2 2.87Å; E181-R184 PolarHBondContact OE2-NH2 3.41Å; A182-R184 PolarHBondContact O-N 2.75Å
185	A	89.4	Confident	86.7	Confident	1 Å²	1	12 Å²	12	1%	0.008	6%	0.062	C	C	.	.	S	Bend	trans	-58.4	161.4	174.9	0	0	0	0	0	112.7	M115 A182 M183 V189 K248	M115-A185 HydrophobicContact CG-CB 4.17Å; A182-A185 WeakPolarHBondContact O-CB 3.31Å; A182-A185 PolarHBondContact O-N 3.03Å; A182-A185 VanDerWaalsContact O-N 3.08Å; M183-A185 VanDerWaalsContact C-N 3.33Å; A185-V189 HydrophobicContact CB-CB 4.41Å; A185-V189 HydrophobicContact CB-CG1 4.22Å; A185-K248 PolarHBondContact O-NZ 3.27Å; A185-K248 VanDerWaalsContact O-NZ 3.14Å
186	P	90.2	Very high	86.3	Confident	0 Å²	0	10.6 Å²	10.6	0%	0	6%	0.056	C	C	.	.			trans	-55.8	144.2	170.8	22	-32.8	0	0	0	111.5	Y68 L78 Y117 Y118 P188 V189 S190	Y68-P186 HydrophobicContact CE1-CB 4.42Å; L78-P186 HydrophobicContact CD1-CG 4.13Å; L78-P186 HydrophobicContact CD2-CB 4.38Å; L78-P186 HydrophobicContact CD2-CG 4.18Å; Y117-P186 HydrophobicContact CD1-CG 4.13Å; Y118-P186 HydrophobicContact CE2-CB 4.01Å; Y118-P186 HydrophobicContact CE2-CG 4.42Å; P186-P188 VanDerWaalsContact C-CD 3.49Å; P186-P188 HydrophobicContact CB-CG 4.16Å; P186-V189 HydrophobicContact CG-CB 4.11Å; P186-V189 HydrophobicContact CG-CG2 3.71Å; P186-V189 WeakPolarHBondContact O-CB 3.5Å; P186-V189 PolarHBondContact O-N 3.41Å; P186-S190 PolarHBondContact O-N 2.95Å; P186-S190 VanDerWaalsContact O-N 3.16Å
187	T	91.1	Very high	86.5	Confident	1 Å²	1	9.1 Å²	9.1	1%	0.006	5%	0.046	C	C	.	.	H	α-helix	trans	-54.6	-41	-178.7	48.4	0	0	0	0	114.5	Y64 Y68 V189 S190 S191 K248 I296	Y64-T187 PolarHBondContact OH-OG1 3.3Å; Y68-T187 WeakPolarHBondContact CD2-OG1 3.26Å; Y68-T187 HydrophobicContact CE2-CG2 4.49Å; Y68-T187 WeakPolarHBondContact CE2-OG1 3.23Å; Y68-T187 VanDerWaalsContact CZ-OG1 3.24Å; T187-V189 VanDerWaalsContact C-N 3.28Å; T187-V189 PolarHBondContact O-N 3.35Å; T187-S190 WeakPolarHBondContact CA-OG 3.32Å; T187-S190 PolarHBondContact O-N 3.36Å; T187-S190 VanDerWaalsContact O-N 3.16Å; T187-S190 PolarHBondContact O-OG 3.49Å; T187-S191 WeakPolarHBondContact O-CB 3.37Å; T187-S191 PolarHBondContact O-N 2.96Å; T187-K248 HydrophobicContact CG2-CD 3.91Å; T187-I296 HydrophobicContact CG2-CD1 4.08Å
188	P	90	Very high	86.9	Confident	0 Å²	0	7.8 Å²	7.8	0%	0	4%	0.036	C	C	.	.	H	α-helix	trans	-58.6	-38.1	174.6	21.3	-35.4	0	0	0	113	Y64 A65 Y68 L78 M82 P186 S191 L192	Y64-P188 HydrophobicContact CD1-CB 3.76Å; Y64-P188 HydrophobicContact CE1-CB 4.19Å; A65-P188 HydrophobicContact CB-CB 3.89Å; A65-P188 HydrophobicContact CB-CG 4.31Å; Y68-P188 HydrophobicContact CD1-CG 4.09Å; L78-P188 HydrophobicContact CD2-CG 3.75Å; M82-P188 HydrophobicContact CE-CB 4.08Å; M82-P188 WeakPolarHBondContact CE-O 3.46Å; M82-P188 HydrophobicContact SD-CB 4.04Å; P186-P188 VanDerWaalsContact C-CD 3.49Å; P186-P188 HydrophobicContact CB-CG 4.16Å; P188-S191 PolarHBondContact O-N 2.87Å; P188-S191 PolarHBondContact O-OG 3.36Å; P188-L192 PolarHBondContact O-N 3.38Å
189	V	91.9	Very high	87.1	Confident	2 Å²	2	7.6 Å²	7.6	1%	0.012	4%	0.035	C	C	.	.	H	α-helix	trans	-65.7	-46.4	175.7	173.3	0	0	0	0	110.4	L78 M82 L114 A185 P186 T187 S191 L192 V193	L78-V189 HydrophobicContact CD1-CG2 3.65Å; L78-V189 HydrophobicContact CD2-CG2 4.47Å; L78-V189 HydrophobicContact CG-CG2 4.34Å; M82-V189 HydrophobicContact CG-CG2 4.16Å; M82-V189 HydrophobicContact SD-CG2 4.19Å; L114-V189 HydrophobicContact CB-CG1 3.84Å; L114-V189 HydrophobicContact CB-CG2 4.47Å; L114-V189 HydrophobicContact CD1-CG1 4.35Å; L114-V189 HydrophobicContact CD2-CG2 4.07Å; A185-V189 HydrophobicContact CB-CB 4.41Å; A185-V189 HydrophobicContact CB-CG1 4.22Å; P186-V189 HydrophobicContact CG-CB 4.11Å; P186-V189 HydrophobicContact CG-CG2 3.71Å; P186-V189 WeakPolarHBondContact O-CB 3.5Å; P186-V189 PolarHBondContact O-N 3.41Å; T187-V189 VanDerWaalsContact C-N 3.28Å; T187-V189 PolarHBondContact O-N 3.35Å; V189-S191 VanDerWaalsContact C-N 3.25Å; V189-S191 PolarHBondContact O-N 3.26Å; V189-L192 PolarHBondContact O-N 2.83Å; V189-L192 VanDerWaalsContact O-N 3.16Å; V189-V193 HydrophobicContact CG1-CB 4.5Å; V189-V193 HydrophobicContact CG1-CG2 3.67Å; V189-V193 WeakPolarHBondContact O-CB 3.36Å; V189-V193 WeakPolarHBondContact O-CG2 3.12Å; V189-V193 PolarHBondContact O-N 3.05Å
190	S	91.8	Very high	87.3	Confident	0 Å²	0	7.8 Å²	7.8	0%	0	4%	0.037	C	C	.	.	H	α-helix	trans	-61.2	-35.3	176.7	61.7	0	0	0	0	113.1	P186 T187 L192 H194	P186-S190 PolarHBondContact O-N 2.95Å; P186-S190 VanDerWaalsContact O-N 3.16Å; T187-S190 WeakPolarHBondContact CA-OG 3.32Å; T187-S190 PolarHBondContact O-N 3.36Å; T187-S190 VanDerWaalsContact O-N 3.16Å; T187-S190 PolarHBondContact O-OG 3.49Å; S190-L192 PolarHBondContact O-N 3.23Å; S190-H194 PolarHBondContact O-N 2.85Å
191	S	90	Very high	87.6	Confident	0 Å²	0	6.4 Å²	6.4	0%	0	3%	0.029	C	C	.	.	H	α-helix	trans	-67	-21.4	179.5	79.8	0	0	0	0	113.6	S61 T187 P188 V189 S195 C286	S61-S191 VanDerWaalsContact CB-OG 3.28Å; S61-S191 WeakPolarHBondContact CB-OG 3.27Å; T187-S191 WeakPolarHBondContact O-CB 3.37Å; T187-S191 PolarHBondContact O-N 2.96Å; P188-S191 PolarHBondContact O-N 2.87Å; P188-S191 PolarHBondContact O-OG 3.36Å; V189-S191 VanDerWaalsContact C-N 3.25Å; V189-S191 PolarHBondContact O-N 3.26Å; S191-S195 WeakPolarHBondContact O-CB 3.46Å; S191-S195 PolarHBondContact O-OG 3.48Å; S191-C286 PolarHBondContact O-SG 3.09Å; S191-C286 VanDerWaalsContact O-SG 3.35Å
192	L	91	Very high	87.9	Confident	2 Å²	2	4.6 Å²	4.6	1%	0.01	2%	0.021	C	C	.	.	H	α-helix	trans	-100.5	-57.6	177.9	-167.8	170.4	0	0	0	109.8	S61 M82 F85 P188 V189 S190 H194 S195 S196 T197	S61-L192 WeakPolarHBondContact OG-CD1 3.23Å; M82-L192 HydrophobicContact CB-CD1 4.27Å; M82-L192 HydrophobicContact CE-CB 4.08Å; M82-L192 HydrophobicContact CE-CD1 3.72Å; F85-L192 HydrophobicContact CD1-CD2 3.32Å; F85-L192 HydrophobicContact CE1-CD2 3.3Å; P188-L192 PolarHBondContact O-N 3.38Å; V189-L192 PolarHBondContact O-N 2.83Å; V189-L192 VanDerWaalsContact O-N 3.16Å; S190-L192 PolarHBondContact O-N 3.23Å; L192-H194 PolarHBondContact O-N 3.48Å; L192-S195 PolarHBondContact O-OG 2.96Å; L192-S196 PolarHBondContact O-N 3.36Å; L192-S196 PolarHBondContact O-OG 3.24Å; L192-T197 HydrophobicContact CD2-CG2 3.61Å; L192-T197 PolarHBondContact O-OG1 3.03Å
193	V	87.8	Confident	88.2	Confident	4 Å²	4	4.6 Å²	4.6	2%	0.024	2%	0.021	C	C	.	.	I	π-helix	trans	-64.7	-43.8	-170.3	179.9	0	0	0	0	112.7	F85 L114 V189 T197 L198	F85-V193 HydrophobicContact CD1-CG2 4.15Å; F85-V193 HydrophobicContact CE1-CB 4.21Å; F85-V193 HydrophobicContact CE1-CG1 4.45Å; F85-V193 HydrophobicContact CE1-CG2 3.6Å; F85-V193 HydrophobicContact CZ-CB 4.25Å; F85-V193 HydrophobicContact CZ-CG1 3.99Å; F85-V193 HydrophobicContact CZ-CG2 3.84Å; L114-V193 HydrophobicContact CD1-CG2 4.06Å; V189-V193 HydrophobicContact CG1-CB 4.5Å; V189-V193 HydrophobicContact CG1-CG2 3.67Å; V189-V193 WeakPolarHBondContact O-CB 3.36Å; V189-V193 WeakPolarHBondContact O-CG2 3.12Å; V189-V193 PolarHBondContact O-N 3.05Å; V193-T197 WeakPolarHBondContact CA-OG1 3.23Å; V193-T197 PolarHBondContact O-OG1 2.89Å; V193-L198 HydrophobicContact CG1-CB 3.96Å; V193-L198 HydrophobicContact CG1-CD1 3.96Å; V193-L198 WeakPolarHBondContact O-CB 3.41Å; V193-L198 PolarHBondContact O-N 2.92Å; V193-L198 VanDerWaalsContact O-N 3.08Å
194	H	79.6	Confident	88.2	Confident	0 Å²	0	4.5 Å²	4.5	0%	0	2%	0.02	C	C	.	.	I	π-helix	trans	-97.9	-10.2	-170.8	-56.1	-49.1	0	0	0	114	L179 A182 M183 S190 L192	L179-H194 HydrophobicContact CD1-CB 4.2Å; A182-H194 WeakPolarHBondContact CB-CE1 2.95Å; A182-H194 VanDerWaalsContact CB-NE2 3.3Å; A182-H194 WeakPolarHBondContact CB-NE2 3.2Å; M183-H194 HydrophobicContact CE-CB 3.71Å; M183-H194 WeakPolarHBondContact CE-CD2 3.46Å; S190-H194 PolarHBondContact O-N 2.85Å; L192-H194 PolarHBondContact O-N 3.48Å
195	S	77.9	Confident	88.5	Confident	3 Å²	3	1.4 Å²	1.4	2%	0.021	1%	0.009	C	C	.	.	I	π-helix	trans	-90.9	-46.4	176.5	63.8	0	0	0	0	112	S191 L192 G282	S191-S195 WeakPolarHBondContact O-CB 3.46Å; S191-S195 PolarHBondContact O-OG 3.48Å; L192-S195 PolarHBondContact O-OG 2.96Å; S195-G282 WeakPolarHBondContact O-CA 3.4Å
196	S	74.4	Confident	88.6	Confident	1 Å²	1	2.2 Å²	2.2	1%	0.007	1%	0.012	C	C	.	.	I	π-helix	trans	-134.6	-15.3	-155.3	61.4	0	0	0	0	115.4	M53 C57 L192 A200	M53-S196 WeakPolarHBondContact CE-O 3.27Å; C57-S196 WeakPolarHBondContact CB-OG 3.21Å; L192-S196 PolarHBondContact O-N 3.36Å; L192-S196 PolarHBondContact O-OG 3.24Å; S196-A200 VanDerWaalsContact O-CB 3.28Å; S196-A200 WeakPolarHBondContact O-CB 3.24Å
197	T	86.7	Confident	88.6	Confident	1 Å²	1	2.6 Å²	2.6	1%	0.006	1%	0.014	C	C	.	.	I	π-helix	trans	-117.4	-69.7	-175.2	60.7	0	0	0	0	113.5	L54 F85 M89 L192 V193 A200 A201	L54-T197 HydrophobicContact CD1-CG2 3.76Å; F85-T197 HydrophobicContact CE1-CG2 3.81Å; F85-T197 WeakPolarHBondContact CE1-OG1 3.37Å; F85-T197 HydrophobicContact CZ-CG2 4.49Å; F85-T197 WeakPolarHBondContact CZ-OG1 3.13Å; M89-T197 HydrophobicContact CB-CG2 4.36Å; M89-T197 HydrophobicContact CG-CG2 4.08Å; L192-T197 HydrophobicContact CD2-CG2 3.61Å; L192-T197 PolarHBondContact O-OG1 3.03Å; V193-T197 WeakPolarHBondContact CA-OG1 3.23Å; V193-T197 PolarHBondContact O-OG1 2.89Å; T197-A200 CarbonylContact O-C 3.51Å; T197-A200 PolarHBondContact O-N 2.95Å; T197-A201 WeakPolarHBondContact O-CB 3.47Å; T197-A201 PolarHBondContact O-N 3.03Å
198	L	88.2	Confident	88.4	Confident	8 Å²	8	3.7 Å²	3.7	4%	0.042	2%	0.019	C	C	.	.	H	α-helix	trans	-69.2	-49.2	-166.9	-166.7	170.2	0	0	0	110.7	L107 K169 W178 V193 A200 A201	L107-L198 HydrophobicContact CD2-CB 3.86Å; L107-L198 HydrophobicContact CD2-CD1 4.35Å; L107-L198 HydrophobicContact CD2-CG 3.62Å; K169-L198 HydrophobicContact CD-CD2 4.49Å; K169-L198 VanDerWaalsContact O-CD2 3.25Å; K169-L198 WeakPolarHBondContact O-CD2 3.5Å; W178-L198 HydrophobicContact CH2-CD1 4.09Å; W178-L198 HydrophobicContact CH2-CD2 3.27Å; W178-L198 HydrophobicContact CH2-CG 4.2Å; W178-L198 HydrophobicContact CZ2-CD2 3.8Å; W178-L198 HydrophobicContact CZ3-CD1 3.94Å; W178-L198 HydrophobicContact CZ3-CD2 3.98Å; V193-L198 HydrophobicContact CG1-CB 3.96Å; V193-L198 HydrophobicContact CG1-CD1 3.96Å; V193-L198 WeakPolarHBondContact O-CB 3.41Å; V193-L198 PolarHBondContact O-N 2.92Å; V193-L198 VanDerWaalsContact O-N 3.08Å; L198-A200 VanDerWaalsContact C-N 3.3Å; L198-A200 PolarHBondContact O-N 3.49Å; L198-A201 PolarHBondContact O-N 3.17Å
199	V	90.5	Very high	88.2	Confident	1 Å²	1	4.1 Å²	4.1	1%	0.006	2%	0.02	C	C	.	.	H	α-helix	trans	-70.5	-32.8	-179.8	-169.7	0	0	0	0	111.1	K169 W178 L179 I259	K169-V199 WeakPolarHBondContact O-CA 3.3Å; W178-V199 HydrophobicContact CH2-CG2 3.98Å; L179-V199 HydrophobicContact CD1-CG2 3.61Å; V199-I259 HydrophobicContact CB-CD1 4.08Å; V199-I259 HydrophobicContact CG1-CB 4.18Å; V199-I259 HydrophobicContact CG1-CD1 3.17Å; V199-I259 HydrophobicContact CG1-CG1 3.63Å; V199-I259 HydrophobicContact CG1-CG2 3.96Å
200	A	91	Very high	88	Confident	4 Å²	4	4.2 Å²	4.2	3%	0.033	2%	0.021	C	C	.	.	H	α-helix	trans	-73.9	-29.6	175.5	0	0	0	0	0	113	M50 M53 S196 T197 L198 G202 M203 W204 L278	M50-A200 HydrophobicContact CE-CB 4.13Å; M53-A200 HydrophobicContact CE-CB 4.28Å; S196-A200 VanDerWaalsContact O-CB 3.28Å; S196-A200 WeakPolarHBondContact O-CB 3.24Å; T197-A200 CarbonylContact O-C 3.51Å; T197-A200 PolarHBondContact O-N 2.95Å; L198-A200 VanDerWaalsContact C-N 3.3Å; L198-A200 PolarHBondContact O-N 3.49Å; A200-G202 VanDerWaalsContact C-N 3.32Å; A200-G202 PolarHBondContact O-N 3.36Å; A200-M203 WeakPolarHBondContact O-CB 3.27Å; A200-M203 PolarHBondContact O-N 3.49Å; A200-M203 VanDerWaalsContact O-N 3.08Å; A200-W204 PolarHBondContact O-N 3.37Å; A200-L278 HydrophobicContact CB-CD1 4.39Å; A200-L278 HydrophobicContact CB-CD2 4.2Å
201	A	91	Very high	87.6	Confident	0 Å²	0	10.8 Å²	10.8	0%	0	5%	0.052	C	C	.	.	H	α-helix	trans	-63.4	-37.7	-178.8	0	0	0	0	0	112	M89 L104 L107 T197 L198 M203 W204 F205	M89-A201 HydrophobicContact CE-CB 4.03Å; M89-A201 HydrophobicContact SD-CB 4Å; L104-A201 HydrophobicContact CD2-CB 3.77Å; L107-A201 HydrophobicContact CD1-CB 4.47Å; T197-A201 WeakPolarHBondContact O-CB 3.47Å; T197-A201 PolarHBondContact O-N 3.03Å; L198-A201 PolarHBondContact O-N 3.17Å; A201-M203 VanDerWaalsContact C-N 3.31Å; A201-M203 PolarHBondContact O-N 3.43Å; A201-W204 PolarHBondContact O-N 3.02Å; A201-F205 WeakPolarHBondContact O-CB 3.4Å; A201-F205 PolarHBondContact O-N 2.84Å
202	G	91.7	Very high	87.1	Confident	0 Å²	0	14 Å²	14	0%	0	7%	0.071	C	C	.	.	H	α-helix	trans	-62.1	-39.1	172.8	0	0	0	0	0	112.5	A200 Y206	A200-G202 VanDerWaalsContact C-N 3.32Å; A200-G202 PolarHBondContact O-N 3.36Å; G202-Y206 PolarHBondContact O-N 3.38Å; G202-Y206 VanDerWaalsContact O-N 3.12Å
203	M	92.8	Very high	86.6	Confident	1 Å²	1	14.8 Å²	14.8	1%	0.005	8%	0.075	C	C	.	.	H	α-helix	trans	-74	-38.7	178.5	-59.9	-44.4	-61.9	0	0	112.6	V166 A200 A201 F205 Y206 L207 I259 V262 V263 M266 L278	V166-M203 HydrophobicContact CG1-SD 4.11Å; A200-M203 WeakPolarHBondContact O-CB 3.27Å; A200-M203 PolarHBondContact O-N 3.49Å; A200-M203 VanDerWaalsContact O-N 3.08Å; A201-M203 VanDerWaalsContact C-N 3.31Å; A201-M203 PolarHBondContact O-N 3.43Å; M203-F205 VanDerWaalsContact C-N 3.35Å; M203-Y206 PolarHBondContact O-N 3.01Å; M203-L207 WeakPolarHBondContact O-CG 3.2Å; M203-L207 PolarHBondContact O-N 3.11Å; M203-I259 HydrophobicContact CG-CG2 4.04Å; M203-I259 HydrophobicContact SD-CG2 4.04Å; M203-V262 HydrophobicContact CE-CB 4.2Å; M203-V262 HydrophobicContact CE-CG1 3.68Å; M203-V262 HydrophobicContact CG-CG1 4.47Å; M203-V263 HydrophobicContact CE-CB 4.05Å; M203-V263 HydrophobicContact CE-CG2 3.3Å; M203-V263 HydrophobicContact SD-CG2 3.39Å; M203-V263 WeakPolarHBondContact SD-CG2 3.42Å; M203-M266 HydrophobicContact CB-CE 4.35Å; M203-M266 HydrophobicContact CE-CE 3.91Å; M203-M266 HydrophobicContact CE-SD 3.35Å; M203-M266 WeakPolarHBondContact CE-SD 3.35Å; M203-L278 HydrophobicContact CB-CD1 3.34Å; M203-L278 HydrophobicContact CG-CD1 3.9Å
204	W	90.8	Very high	86.1	Confident	1 Å²	1	20.6 Å²	20.6	0%	0.004	10%	0.1	C	C	.	.	H	α-helix	trans	-60.4	-45	171.7	170.7	79.2	0	0	0	111.4	M50 L92 A200 A201 Y206 L207 E208 Y209	M50-W204 HydrophobicContact CE-CB 4.26Å; L92-W204 HydrophobicContact CD1-CZ3 4.34Å; L92-W204 HydrophobicContact CD2-CD2 4.05Å; L92-W204 HydrophobicContact CD2-CE3 3.42Å; L92-W204 VanDerWaalsContact CD2-CE3 3.42Å; L92-W204 HydrophobicContact CD2-CH2 3.86Å; L92-W204 HydrophobicContact CD2-CZ2 4.44Å; L92-W204 HydrophobicContact CD2-CZ3 3.33Å; L92-W204 HydrophobicContact CG-CE3 4.32Å; L92-W204 HydrophobicContact CG-CH2 4Å; L92-W204 HydrophobicContact CG-CZ3 3.71Å; L92-W204 VanDerWaalsContact O-CH2 3.24Å; L92-W204 WeakPolarHBondContact O-CH2 3.47Å; L92-W204 WeakPolarHBondContact O-CZ2 3.23Å; A200-W204 PolarHBondContact O-N 3.37Å; A201-W204 PolarHBondContact O-N 3.02Å; W204-Y206 VanDerWaalsContact C-N 3.29Å; W204-Y206 PolarHBondContact O-N 3.3Å; W204-L207 WeakPolarHBondContact O-CB 3.34Å; W204-L207 PolarHBondContact O-N 3.03Å; W204-L207 VanDerWaalsContact O-N 3.11Å; W204-E208 HydrophobicContact CD2-CG 4.4Å; W204-E208 HydrophobicContact CZ2-CG 4.04Å; W204-E208 PolarHBondContact O-N 3.17Å; W204-Y209 HydrophobicContact CH2-CE2 4.33Å; W204-Y209 HydrophobicContact CZ3-CE2 4.41Å
205	F	91	Very high	85.9	Confident	0 Å²	0	21.5 Å²	21.5	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-59.3	-41.4	176	174.5	-101.4	0	0	0	111.7	T101 L104 L144 M162 V165 V166 A201 M203 Y209	T101-F205 HydrophobicContact CG2-CD2 4.06Å; T101-F205 HydrophobicContact CG2-CE2 4.02Å; L104-F205 HydrophobicContact CD1-CB 4.45Å; L104-F205 HydrophobicContact CD1-CD2 4.1Å; L104-F205 HydrophobicContact CD1-CG 4.32Å; L144-F205 HydrophobicContact CD1-CZ 4.27Å; L144-F205 HydrophobicContact CD2-CZ 4.34Å; M162-F205 HydrophobicContact CE-CD1 3.91Å; M162-F205 HydrophobicContact CE-CE1 3.49Å; M162-F205 VanDerWaalsContact CE-CE1 3.49Å; M162-F205 HydrophobicContact CE-CZ 4.08Å; M162-F205 HydrophobicContact SD-CD1 4.19Å; M162-F205 HydrophobicContact SD-CE1 3.18Å; M162-F205 WeakPolarHBondContact SD-CE1 3.47Å; M162-F205 HydrophobicContact SD-CZ 3.43Å; M162-F205 WeakPolarHBondContact SD-CZ 3.34Å; V165-F205 HydrophobicContact CB-CD1 4.28Å; V165-F205 HydrophobicContact CB-CE1 3.87Å; V165-F205 HydrophobicContact CG1-CD1 3.64Å; V165-F205 HydrophobicContact CG1-CE1 3.58Å; V165-F205 HydrophobicContact CG1-CG 4.31Å; V165-F205 HydrophobicContact CG1-CZ 4.25Å; V165-F205 HydrophobicContact CG2-CE1 4.31Å; V166-F205 HydrophobicContact CG2-CD1 4.49Å; A201-F205 WeakPolarHBondContact O-CB 3.4Å; A201-F205 PolarHBondContact O-N 2.84Å; M203-F205 VanDerWaalsContact C-N 3.35Å; F205-Y209 AromaticContact CD2-CD2 3.43Å; F205-Y209 HydrophobicContact CD2-CD2 3.43Å; F205-Y209 VanDerWaalsContact CD2-CD2 3.43Å; F205-Y209 AromaticContact CD2-CE2 3.87Å; F205-Y209 HydrophobicContact CD2-CE2 3.87Å; F205-Y209 HydrophobicContact CD2-CG 4.39Å; F205-Y209 AromaticContact CE2-CD2 3.65Å; F205-Y209 HydrophobicContact CE2-CD2 3.65Å; F205-Y209 HydrophobicContact CE2-CE2 4.21Å; F205-Y209 HydrophobicContact CE2-CG 4.23Å; F205-Y209 HydrophobicContact CG-CD2 4.21Å; F205-Y209 WeakPolarHBondContact O-CB 3.5Å; F205-Y209 WeakPolarHBondContact O-CD2 3.33Å; F205-Y209 PolarHBondContact O-N 3.1Å; F205-Y209 VanDerWaalsContact O-N 3.12Å
206	Y	91.9	Very high	86.2	Confident	17 Å²	17	22.7 Å²	22.7	7%	0.067	11%	0.111	C	C	.	.	H	α-helix	trans	-63.3	-44.6	173.5	-171.6	-90.2	0	0	0	112.2	M162 V166 G202 M203 W204 E208 S210 F216 M266 Y271	M162-Y206 HydrophobicContact CE-CD2 4.43Å; V166-Y206 HydrophobicContact CG2-CD2 4.07Å; V166-Y206 HydrophobicContact CG2-CG 4.46Å; G202-Y206 PolarHBondContact O-N 3.38Å; G202-Y206 VanDerWaalsContact O-N 3.12Å; M203-Y206 PolarHBondContact O-N 3.01Å; W204-Y206 VanDerWaalsContact C-N 3.29Å; W204-Y206 PolarHBondContact O-N 3.3Å; Y206-E208 PolarHBondContact O-N 3.01Å; Y206-S210 WeakPolarHBondContact O-CA 3.11Å; Y206-S210 WeakPolarHBondContact O-CB 3.35Å; Y206-S210 PolarHBondContact O-N 3.23Å; Y206-S210 PolarHBondContact O-OG 3.42Å; Y206-F216 HydrophobicContact CE2-CE2 4.1Å; Y206-M266 HydrophobicContact CD1-CB 3.83Å; Y206-M266 HydrophobicContact CD1-CG 4.29Å; Y206-M266 HydrophobicContact CD1-SD 3.67Å; Y206-M266 HydrophobicContact CE1-CB 3.57Å; Y206-M266 HydrophobicContact CE1-CG 4.47Å; Y206-M266 HydrophobicContact CE1-SD 4.39Å; Y206-M266 HydrophobicContact CG-SD 4.47Å; Y206-Y271 AromaticContact CE1-CE1 3.93Å; Y206-Y271 HydrophobicContact CE1-CE1 3.93Å
207	L	89.9	Confident	86.4	Confident	9 Å²	9	28 Å²	28	5%	0.047	14%	0.136	C	C	.	.	H	α-helix	trans	-58.7	-48.6	-180	-80.3	170.2	0	0	0	113	I46 M203 W204 M266 Y271 L275	I46-L207 HydrophobicContact CD1-CB 4.48Å; I46-L207 HydrophobicContact CG2-CB 4.2Å; I46-L207 HydrophobicContact CG2-CD1 4.15Å; M203-L207 WeakPolarHBondContact O-CG 3.2Å; M203-L207 PolarHBondContact O-N 3.11Å; W204-L207 WeakPolarHBondContact O-CB 3.34Å; W204-L207 PolarHBondContact O-N 3.03Å; W204-L207 VanDerWaalsContact O-N 3.11Å; L207-M266 HydrophobicContact CD1-CE 3.57Å; L207-M266 HydrophobicContact CD2-CE 3.61Å; L207-M266 HydrophobicContact CD2-CG 4.36Å; L207-M266 HydrophobicContact CD2-SD 4.05Å; L207-M266 HydrophobicContact CG-CE 3.4Å; L207-M266 VanDerWaalsContact CG-CE 3.4Å; L207-M266 HydrophobicContact CG-SD 3.95Å; L207-Y271 HydrophobicContact CD2-CD1 3.95Å; L207-Y271 HydrophobicContact CD2-CG 4.48Å; L207-L275 HydrophobicContact CD1-CB 4.34Å; L207-L275 HydrophobicContact CD1-CD1 4.18Å
208	E	86.4	Confident	86	Confident	24 Å²	24	31.9 Å²	31.9	11%	0.112	18%	0.176	C	C	.	.	H	α-helix	trans	-74.4	-42.2	-175.8	-67.1	-70.7	173.9	0	0	112	S44 I46 W204 Y206	S44-E208 PolarHBondContact OG-OE1 3.45Å; I46-E208 WeakPolarHBondContact CB-OE1 3.11Å; I46-E208 HydrophobicContact CG2-CG 4.44Å; I46-E208 VanDerWaalsContact CG2-OE1 3.31Å; I46-E208 WeakPolarHBondContact CG2-OE1 3.42Å; W204-E208 HydrophobicContact CD2-CG 4.4Å; W204-E208 HydrophobicContact CZ2-CG 4.04Å; W204-E208 PolarHBondContact O-N 3.17Å; Y206-E208 PolarHBondContact O-N 3.01Å
209	Y	86.9	Confident	86	Confident	8 Å²	8	31.8 Å²	31.8	3%	0.031	18%	0.176	C	C	.	.	H	α-helix	trans	-101.9	-9.9	-169.3	-60.5	-73.3	0	0	0	114.9	Y96 E97 V98 T101 W204 F205 Q211 V212 M213	Y96-Y209 PolarHBondContact O-OH 2.78Å; E97-Y209 PolarHBondContact O-OH 2.87Å; V98-Y209 HydrophobicContact CB-CE1 4.15Å; V98-Y209 HydrophobicContact CG1-CD1 4.31Å; V98-Y209 HydrophobicContact CG1-CE1 4.15Å; V98-Y209 HydrophobicContact CG2-CD1 4.19Å; V98-Y209 HydrophobicContact CG2-CE1 3.8Å; T101-Y209 HydrophobicContact CG2-CD2 4.07Å; T101-Y209 HydrophobicContact CG2-CE1 4.27Å; T101-Y209 HydrophobicContact CG2-CE2 3.19Å; T101-Y209 VanDerWaalsContact CG2-OH 3.22Å; T101-Y209 WeakPolarHBondContact CG2-OH 3.32Å; W204-Y209 HydrophobicContact CH2-CE2 4.33Å; W204-Y209 HydrophobicContact CZ3-CE2 4.41Å; F205-Y209 AromaticContact CD2-CD2 3.43Å; F205-Y209 HydrophobicContact CD2-CD2 3.43Å; F205-Y209 VanDerWaalsContact CD2-CD2 3.43Å; F205-Y209 AromaticContact CD2-CE2 3.87Å; F205-Y209 HydrophobicContact CD2-CE2 3.87Å; F205-Y209 HydrophobicContact CD2-CG 4.39Å; F205-Y209 AromaticContact CE2-CD2 3.65Å; F205-Y209 HydrophobicContact CE2-CD2 3.65Å; F205-Y209 HydrophobicContact CE2-CE2 4.21Å; F205-Y209 HydrophobicContact CE2-CG 4.23Å; F205-Y209 HydrophobicContact CG-CD2 4.21Å; F205-Y209 WeakPolarHBondContact O-CB 3.5Å; F205-Y209 WeakPolarHBondContact O-CD2 3.33Å; F205-Y209 PolarHBondContact O-N 3.1Å; F205-Y209 VanDerWaalsContact O-N 3.12Å; Y209-Q211 VanDerWaalsContact C-N 3.32Å; Y209-Q211 PolarHBondContact O-N 3.3Å; Y209-V212 PolarHBondContact O-N 3.06Å; Y209-M213 VanDerWaalsContact O-CB 3.29Å; Y209-M213 WeakPolarHBondContact O-CB 3.21Å; Y209-M213 VanDerWaalsContact O-CG 3.24Å; Y209-M213 WeakPolarHBondContact O-CG 3.41Å; Y209-M213 PolarHBondContact O-N 3.4Å
210	S	86.6	Confident	85.9	Confident	5 Å²	5	36.3 Å²	36.3	4%	0.035	21%	0.208	C	C	.	.	H	α-helix	trans	-58.1	-43.3	179.5	53.5	0	0	0	0	112.9	Y206 K214 C215	Y206-S210 WeakPolarHBondContact O-CA 3.11Å; Y206-S210 WeakPolarHBondContact O-CB 3.35Å; Y206-S210 PolarHBondContact O-N 3.23Å; Y206-S210 PolarHBondContact O-OG 3.42Å; S210-K214 PolarHBondContact O-N 3.49Å; S210-C215 PolarHBondContact O-N 3.37Å
211	Q	84.1	Confident	85.8	Confident	137 Å²	137	42.3 Å²	42.3	64%	0.64	24%	0.239	S	C	*	.	H	α-helix	trans	-74.4	-43	179	-63.5	-175.2	-2	0	0	111.6	Y209 M213 K214	Y209-Q211 VanDerWaalsContact C-N 3.32Å; Y209-Q211 PolarHBondContact O-N 3.3Å; Q211-M213 VanDerWaalsContact C-N 3.31Å; Q211-M213 PolarHBondContact O-N 2.94Å; Q211-K214 PolarHBondContact O-N 3.26Å
212	V	80	Confident	85.9	Confident	67 Å²	67	43.8 Å²	43.8	41%	0.406	25%	0.247	S	C	.	.	H	α-helix	trans	-61.2	-41.7	-179.9	178.9	0	0	0	0	111.3	Y148 Y209 K214	Y148-V212 HydrophobicContact CE2-CG1 4.08Å; Y209-V212 PolarHBondContact O-N 3.06Å; V212-K214 VanDerWaalsContact C-N 3.32Å; V212-K214 PolarHBondContact O-N 3.46Å
213	M	79.1	Confident	85.8	Confident	19 Å²	19	47.3 Å²	47.3	9%	0.094	26%	0.26	C	S	.	.	T	Hydrogen-bonded Turn	trans	-88.5	3.2	-175.9	-58.9	-63.1	-75	0	0	113.4	L144 Y148 V158 Y209 Q211 C215	L144-M213 HydrophobicContact CD1-CE 4.05Å; L144-M213 HydrophobicContact CD2-CE 3.43Å; L144-M213 VanDerWaalsContact CD2-CE 3.43Å; L144-M213 HydrophobicContact CD2-SD 4.3Å; L144-M213 HydrophobicContact CG-CE 3.5Å; L144-M213 VanDerWaalsContact CG-CE 3.5Å; Y148-M213 HydrophobicContact CD2-CE 4.33Å; Y148-M213 HydrophobicContact CD2-SD 3.54Å; Y148-M213 VanDerWaalsContact CD2-SD 3.54Å; Y148-M213 HydrophobicContact CE2-SD 4.28Å; Y148-M213 HydrophobicContact CG-SD 4.29Å; V158-M213 HydrophobicContact CG1-CB 3.93Å; V158-M213 HydrophobicContact CG1-CE 3.71Å; Y209-M213 VanDerWaalsContact O-CB 3.29Å; Y209-M213 WeakPolarHBondContact O-CB 3.21Å; Y209-M213 VanDerWaalsContact O-CG 3.24Å; Y209-M213 WeakPolarHBondContact O-CG 3.41Å; Y209-M213 PolarHBondContact O-N 3.4Å; Q211-M213 VanDerWaalsContact C-N 3.31Å; Q211-M213 PolarHBondContact O-N 2.94Å; M213-C215 PolarHBondContact O-N 3.04Å
214	K	76.9	Confident	85.8	Confident	127 Å²	127	50.4 Å²	50.4	55%	0.552	28%	0.282	S	S	*	.	T	Hydrogen-bonded Turn	trans	49.7	46.2	-179.3	-68.2	-176.2	179.1	-175.3	0	112.5	S210 Q211 V212 F216 E217	S210-K214 PolarHBondContact O-N 3.49Å; Q211-K214 PolarHBondContact O-N 3.26Å; V212-K214 VanDerWaalsContact C-N 3.32Å; V212-K214 PolarHBondContact O-N 3.46Å; K214-F216 PolarHBondContact O-N 3.09Å; K214-E217 HydrophobicContact CB-CG 4.13Å; K214-E217 WeakPolarHBondContact CG-OE1 3.32Å; K214-E217 PolarHBondContact O-N 3.25Å
215	C	76.9	Confident	85.8	Confident	19 Å²	19	55.7 Å²	55.7	13%	0.128	31%	0.305	C	S	.	.	T	Hydrogen-bonded Turn	trans	-59.7	138	-173.4	-69.9	0	0	0	0	111.6	M162 S210 M213 E217	M162-C215 VanDerWaalsContact CG-SG 3.6Å; S210-C215 PolarHBondContact O-N 3.37Å; M213-C215 PolarHBondContact O-N 3.04Å; C215-E217 PolarHBondContact O-N 3.42Å
216	F	83	Confident	85.9	Confident	28 Å²	28	56 Å²	56	12%	0.123	31%	0.308	C	S	.	.	T	Hydrogen-bonded Turn	trans	67.1	2.8	177.7	-53.2	-73.7	0	0	0	116.5	Y206 K214 G218 C219 L222 Y223 L267	Y206-F216 HydrophobicContact CE2-CE2 4.1Å; K214-F216 PolarHBondContact O-N 3.09Å; F216-G218 PolarHBondContact O-N 2.75Å; F216-G218 VanDerWaalsContact O-N 3.08Å; F216-C219 PolarHBondContact O-N 2.92Å; F216-C219 VanDerWaalsContact O-N 3.07Å; F216-L222 HydrophobicContact CD1-CB 4.2Å; F216-L222 HydrophobicContact CE1-CB 4.21Å; F216-Y223 HydrophobicContact CB-CD2 4.47Å; F216-Y223 HydrophobicContact CD2-CD2 4.46Å; F216-Y223 HydrophobicContact CG-CD2 4.26Å; F216-L267 HydrophobicContact CE2-CD2 3.79Å; F216-L267 HydrophobicContact CZ-CD2 4.07Å
217	E	79.1	Confident	85.9	Confident	111 Å²	111	55.9 Å²	55.9	52%	0.519	31%	0.308	S	S	.	.	T	Hydrogen-bonded Turn	trans	-58.4	116.5	172.5	-73.6	-172.5	-171.6	0	0	110.6	S155 K214 C215 C219	S155-E217 VanDerWaalsContact CB-O 3.23Å; S155-E217 WeakPolarHBondContact CB-O 3.26Å; S155-E217 PolarHBondContact OG-O 3.31Å; K214-E217 HydrophobicContact CB-CG 4.13Å; K214-E217 WeakPolarHBondContact CG-OE1 3.32Å; K214-E217 PolarHBondContact O-N 3.25Å; C215-E217 PolarHBondContact O-N 3.42Å; E217-C219 VanDerWaalsContact C-N 3.28Å; E217-C219 PolarHBondContact O-N 2.89Å
218	G	78	Confident	86.1	Confident	83 Å²	83	57.5 Å²	57.5	86%	0.856	32%	0.323	S	S	*	.	T	Hydrogen-bonded Turn	trans	78	-2	-179.1	0	0	0	0	0	116	F216	F216-G218 PolarHBondContact O-N 2.75Å; F216-G218 VanDerWaalsContact O-N 3.08Å
219	C	87.4	Confident	86.3	Confident	7 Å²	7	57 Å²	57	5%	0.047	32%	0.321	C	S	.	.			trans	-115.6	63.9	-173.3	-54.6	0	0	0	0	112.1	S155 C156 F216 E217 L221 L222 Y223	S155-C219 PolarHBondContact OG-SG 3.46Å; S155-C219 VanDerWaalsContact OG-SG 3.4Å; C156-C219 WeakPolarHBondContact CA-SG 3.33Å; C156-C219 HydrophobicContact CB-CB 4.14Å; C156-C219 WeakPolarHBondContact CB-SG 3.34Å; C156-C219 PolarHBondContact N-SG 2.92Å; C156-C219 WeakPolarHBondContact SG-CB 3.37Å; C156-C219 CovalentContact SG-SG 2.04Å; C156-C219 PolarHBondContact SG-SG 3.02Å; F216-C219 PolarHBondContact O-N 2.92Å; F216-C219 VanDerWaalsContact O-N 3.07Å; E217-C219 VanDerWaalsContact C-N 3.28Å; E217-C219 PolarHBondContact O-N 2.89Å; C219-L221 PolarHBondContact O-N 3.01Å; C219-L222 HydrophobicContact CB-CB 4.3Å; C219-L222 HydrophobicContact CB-CD1 4.17Å; C219-L222 PolarHBondContact O-N 3.21Å; C219-L222 VanDerWaalsContact O-N 3.16Å; C219-Y223 PolarHBondContact O-N 3.04Å; C219-Y223 VanDerWaalsContact O-N 3.14Å
220	S	88.4	Confident	86.7	Confident	96 Å²	96	56.6 Å²	56.6	67%	0.671	32%	0.32	S	S	*	.	H	α-helix	trans	-58.8	-32.1	-177.4	60.3	0	0	0	0	114	Y223 S224	S220-Y223 PolarHBondContact O-N 3.49Å; S220-S224 PolarHBondContact O-N 3.2Å; S220-S224 PolarHBondContact O-OG 3.42Å
221	L	90.8	Very high	87.1	Confident	130 Å²	130	57.7 Å²	57.7	68%	0.681	33%	0.325	S	S	*	.	H	α-helix	trans	-69.4	-39.7	178.1	-169.7	150	0	0	0	112.2	C219 Y223 S224 F225	C219-L221 PolarHBondContact O-N 3.01Å; L221-Y223 VanDerWaalsContact C-N 3.34Å; L221-S224 PolarHBondContact O-N 2.95Å; L221-S224 PolarHBondContact O-OG 3Å; L221-F225 VanDerWaalsContact O-CB 3.29Å; L221-F225 WeakPolarHBondContact O-CB 3.22Å; L221-F225 PolarHBondContact O-N 3.48Å
222	L	91.4	Very high	87.4	Confident	31 Å²	31	55 Å²	55	16%	0.162	31%	0.314	C	S	.	.	H	α-helix	trans	-69.9	-36.7	176.2	-72.6	174.5	0	0	0	111.2	C156 S159 L160 F216 C219 F225 S226	C156-L222 HydrophobicContact CB-CD1 3.76Å; C156-L222 WeakPolarHBondContact O-CD1 3.18Å; S159-L222 WeakPolarHBondContact OG-CD1 3.41Å; L160-L222 HydrophobicContact CB-CD1 4.37Å; L160-L222 HydrophobicContact CD1-CD2 4.35Å; F216-L222 HydrophobicContact CD1-CB 4.2Å; F216-L222 HydrophobicContact CE1-CB 4.21Å; C219-L222 HydrophobicContact CB-CB 4.3Å; C219-L222 HydrophobicContact CB-CD1 4.17Å; C219-L222 PolarHBondContact O-N 3.21Å; C219-L222 VanDerWaalsContact O-N 3.16Å; L222-F225 PolarHBondContact O-N 3.31Å; L222-S226 WeakPolarHBondContact O-CB 3.39Å; L222-S226 PolarHBondContact O-N 3.17Å
223	Y	91.2	Very high	87.9	Confident	74 Å²	74	52 Å²	52	29%	0.29	30%	0.297	S	S	.	.	H	α-helix	trans	-60	-50.8	172.6	177.5	-94.9	0	0	0	111.6	F216 C219 S220 L221 F225 S226 M227 L267	F216-Y223 HydrophobicContact CB-CD2 4.47Å; F216-Y223 HydrophobicContact CD2-CD2 4.46Å; F216-Y223 HydrophobicContact CG-CD2 4.26Å; C219-Y223 PolarHBondContact O-N 3.04Å; C219-Y223 VanDerWaalsContact O-N 3.14Å; S220-Y223 PolarHBondContact O-N 3.49Å; L221-Y223 VanDerWaalsContact C-N 3.34Å; Y223-F225 VanDerWaalsContact C-N 3.33Å; Y223-F225 PolarHBondContact O-N 2.97Å; Y223-S226 PolarHBondContact O-N 3.29Å; Y223-S226 PolarHBondContact O-OG 3.28Å; Y223-M227 PolarHBondContact O-N 3.39Å; Y223-L267 HydrophobicContact CD2-CD2 4.36Å; Y223-L267 HydrophobicContact CE2-CB 4.03Å; Y223-L267 HydrophobicContact CE2-CD2 4.24Å; Y223-L267 VanDerWaalsContact CE2-O 3.24Å; Y223-L267 WeakPolarHBondContact CE2-O 3.37Å; Y223-L267 PolarHBondContact OH-O 2.88Å; Y223-L267 VanDerWaalsContact OH-O 3.08Å
224	S	90.8	Very high	88.6	Confident	66 Å²	66	51.3 Å²	51.3	46%	0.462	29%	0.293	S	S	.	.	H	α-helix	trans	-65	-36.6	179.2	64.5	0	0	0	0	112.6	S220 L221 M227 A228	S220-S224 PolarHBondContact O-N 3.2Å; S220-S224 PolarHBondContact O-OG 3.42Å; L221-S224 PolarHBondContact O-N 2.95Å; L221-S224 PolarHBondContact O-OG 3Å; S224-M227 PolarHBondContact O-N 3.48Å; S224-A228 WeakPolarHBondContact O-CB 3.47Å; S224-A228 PolarHBondContact O-N 3.26Å
225	F	92.2	Very high	89.2	Confident	112 Å²	112	47.5 Å²	47.5	49%	0.491	28%	0.279	S	S	.	.	H	α-helix	trans	-61.8	-46.4	172.7	-179	-101.8	0	0	0	111.9	L163 L221 L222 Y223 M227 A228 C229	L163-F225 HydrophobicContact CD1-CD1 4.36Å; L163-F225 HydrophobicContact CD2-CE1 4.44Å; L221-F225 VanDerWaalsContact O-CB 3.29Å; L221-F225 WeakPolarHBondContact O-CB 3.22Å; L221-F225 PolarHBondContact O-N 3.48Å; L222-F225 PolarHBondContact O-N 3.31Å; Y223-F225 VanDerWaalsContact C-N 3.33Å; Y223-F225 PolarHBondContact O-N 2.97Å; F225-M227 VanDerWaalsContact C-N 3.33Å; F225-M227 PolarHBondContact O-N 3.1Å; F225-A228 PolarHBondContact O-N 3.44Å; F225-C229 PolarHBondContact O-N 2.98Å; F225-C229 PolarHBondContact O-SG 2.71Å
226	S	92.5	Very high	89.7	Confident	7 Å²	7	49 Å²	49	5%	0.049	29%	0.285	C	S	.	.	H	α-helix	trans	-60.2	-42.6	178.1	76.8	0	0	0	0	112.6	L222 Y223 C229 A230 L267	L222-S226 WeakPolarHBondContact O-CB 3.39Å; L222-S226 PolarHBondContact O-N 3.17Å; Y223-S226 PolarHBondContact O-N 3.29Å; Y223-S226 PolarHBondContact O-OG 3.28Å; S226-C229 PolarHBondContact O-N 2.79Å; S226-A230 PolarHBondContact O-N 2.99Å; S226-L267 WeakPolarHBondContact OG-CD1 3.49Å; S226-L267 VanDerWaalsContact OG-CD2 3.32Å; S226-L267 WeakPolarHBondContact OG-CD2 3.3Å
227	M	92.7	Very high	89.9	Confident	14 Å²	14	48 Å²	48	7%	0.069	28%	0.281	C	S	.	.	H	α-helix	trans	-64	-43.5	176	-173.4	70.7	-158.3	0	0	110.8	Y223 S224 F225 A230 L231 V264 L267 L358	Y223-M227 PolarHBondContact O-N 3.39Å; S224-M227 PolarHBondContact O-N 3.48Å; F225-M227 VanDerWaalsContact C-N 3.33Å; F225-M227 PolarHBondContact O-N 3.1Å; M227-A230 PolarHBondContact O-N 2.84Å; M227-L231 HydrophobicContact CE-CD1 3.77Å; M227-L231 HydrophobicContact CE-CD2 3.78Å; M227-L231 HydrophobicContact CE-CG 3.73Å; M227-L231 HydrophobicContact CG-CD1 4.08Å; M227-L231 VanDerWaalsContact O-CG 3.3Å; M227-L231 WeakPolarHBondContact O-CG 3.38Å; M227-L231 PolarHBondContact O-N 3.48Å; M227-V264 HydrophobicContact CE-CB 4.05Å; M227-V264 HydrophobicContact CE-CG1 3.32Å; M227-V264 HydrophobicContact CE-CG2 3.62Å; M227-V264 HydrophobicContact SD-CB 4.4Å; M227-V264 HydrophobicContact SD-CG1 4.05Å; M227-V264 HydrophobicContact SD-CG2 3.98Å; M227-L267 HydrophobicContact CB-CD1 4.35Å; M227-L267 HydrophobicContact SD-CD1 4.26Å; M227-L358 HydrophobicContact CE-CD1 3.31Å; M227-L358 HydrophobicContact CE-CD2 4.47Å; M227-L358 HydrophobicContact CE-CG 3.88Å; M227-L358 HydrophobicContact CG-CD1 4.48Å; M227-L358 HydrophobicContact SD-CD1 4.27Å
228	A	92.8	Very high	90.3	Very high	43 Å²	43	42.8 Å²	42.8	36%	0.355	26%	0.257	S	S	.	.	H	α-helix	trans	-62.7	-43.7	177	0	0	0	0	0	111.8	S224 F225 A230 L231 L232	S224-A228 WeakPolarHBondContact O-CB 3.47Å; S224-A228 PolarHBondContact O-N 3.26Å; F225-A228 PolarHBondContact O-N 3.44Å; A228-A230 VanDerWaalsContact C-N 3.34Å; A228-A230 PolarHBondContact O-N 3.26Å; A228-L231 PolarHBondContact O-N 3.31Å; A228-L232 WeakPolarHBondContact O-CB 3.41Å; A228-L232 VanDerWaalsContact O-CG 3.23Å; A228-L232 WeakPolarHBondContact O-CG 2.91Å; A228-L232 PolarHBondContact O-N 3.45Å
229	C	92.3	Very high	90.6	Very high	13 Å²	13	41.2 Å²	41.2	9%	0.088	23%	0.231	C	C	.	.	H	α-helix	trans	-57.2	-46.5	174.4	-74.3	0	0	0	0	111.6	F225 S226 L232 T233	F225-C229 PolarHBondContact O-N 2.98Å; F225-C229 PolarHBondContact O-SG 2.71Å; S226-C229 PolarHBondContact O-N 2.79Å; C229-L232 PolarHBondContact O-N 2.88Å; C229-T233 VanDerWaalsContact O-CG2 3.27Å; C229-T233 WeakPolarHBondContact O-CG2 3.07Å; C229-T233 PolarHBondContact O-N 3.41Å; C229-T233 PolarHBondContact O-OG1 3.33Å
230	A	94.4	Very high	90.4	Very high	0 Å²	0	45 Å²	45	0%	0	25%	0.245	C	C	.	.	H	α-helix	trans	-69.5	-33.6	179.8	0	0	0	0	0	113.4	S226 M227 A228 T233 M234 V263 V264	S226-A230 PolarHBondContact O-N 2.99Å; M227-A230 PolarHBondContact O-N 2.84Å; A228-A230 VanDerWaalsContact C-N 3.34Å; A228-A230 PolarHBondContact O-N 3.26Å; A230-T233 VanDerWaalsContact C-OG1 3.26Å; A230-T233 WeakPolarHBondContact CA-OG1 3.41Å; A230-T233 PolarHBondContact O-OG1 3.08Å; A230-M234 WeakPolarHBondContact O-CE 3.39Å; A230-M234 WeakPolarHBondContact O-CG 3.12Å; A230-M234 PolarHBondContact O-N 3.25Å; A230-V263 HydrophobicContact CB-CB 4.22Å; A230-V263 HydrophobicContact CB-CG1 3.85Å; A230-V264 HydrophobicContact CB-CG2 3.65Å
231	L	94.3	Very high	90.2	Very high	28 Å²	28	40.4 Å²	40.4	15%	0.147	21%	0.213	C	C	.	.	H	α-helix	trans	-70	-44.5	173.6	-70.2	168.9	0	0	0	111.3	M227 A228 T233 M234 L235 V361 M362	M227-L231 HydrophobicContact CE-CD1 3.77Å; M227-L231 HydrophobicContact CE-CD2 3.78Å; M227-L231 HydrophobicContact CE-CG 3.73Å; M227-L231 HydrophobicContact CG-CD1 4.08Å; M227-L231 VanDerWaalsContact O-CG 3.3Å; M227-L231 WeakPolarHBondContact O-CG 3.38Å; M227-L231 PolarHBondContact O-N 3.48Å; A228-L231 PolarHBondContact O-N 3.31Å; L231-T233 VanDerWaalsContact C-N 3.34Å; L231-T233 PolarHBondContact O-N 3.16Å; L231-M234 HydrophobicContact CD2-CE 3.67Å; L231-M234 HydrophobicContact CG-CE 4.4Å; L231-M234 PolarHBondContact O-N 3.38Å; L231-L235 WeakPolarHBondContact O-CG 3.34Å; L231-L235 PolarHBondContact O-N 2.89Å; L231-L235 VanDerWaalsContact O-N 3.1Å; L231-V361 HydrophobicContact CD2-CG1 3.84Å; L231-M362 HydrophobicContact CD2-SD 3.49Å; L231-M362 WeakPolarHBondContact CD2-SD 3.39Å
232	L	90.8	Very high	89.8	Confident	79 Å²	79	35.3 Å²	35.3	41%	0.414	19%	0.187	S	C	.	.	H	α-helix	trans	-62.2	-41	178	-73.9	171.3	0	0	0	111.6	A228 C229 M234 L235 I236	A228-L232 WeakPolarHBondContact O-CB 3.41Å; A228-L232 VanDerWaalsContact O-CG 3.23Å; A228-L232 WeakPolarHBondContact O-CG 2.91Å; A228-L232 PolarHBondContact O-N 3.45Å; C229-L232 PolarHBondContact O-N 2.88Å; L232-M234 PolarHBondContact O-N 2.79Å; L232-L235 PolarHBondContact O-N 3.45Å; L232-I236 HydrophobicContact CB-CD1 4.43Å; L232-I236 WeakPolarHBondContact O-CB 3.13Å; L232-I236 VanDerWaalsContact O-CG1 3.23Å; L232-I236 WeakPolarHBondContact O-CG1 3.37Å; L232-I236 PolarHBondContact O-N 2.95Å
233	T	90.6	Very high	89.2	Confident	6 Å²	6	36.3 Å²	36.3	4%	0.037	19%	0.191	C	C	.	.	H	α-helix	trans	-60.9	-44.2	175.1	47	0	0	0	0	112.4	L172 F173 C229 A230 L231 L235 S237 S260	L172-T233 HydrophobicContact CB-CG2 4.16Å; L172-T233 HydrophobicContact CD2-CG2 4.13Å; F173-T233 HydrophobicContact CB-CG2 3.34Å; C229-T233 VanDerWaalsContact O-CG2 3.27Å; C229-T233 WeakPolarHBondContact O-CG2 3.07Å; C229-T233 PolarHBondContact O-N 3.41Å; C229-T233 PolarHBondContact O-OG1 3.33Å; A230-T233 VanDerWaalsContact C-OG1 3.26Å; A230-T233 WeakPolarHBondContact CA-OG1 3.41Å; A230-T233 PolarHBondContact O-OG1 3.08Å; L231-T233 VanDerWaalsContact C-N 3.34Å; L231-T233 PolarHBondContact O-N 3.16Å; T233-L235 VanDerWaalsContact C-N 3.33Å; T233-L235 PolarHBondContact O-N 2.97Å; T233-S237 WeakPolarHBondContact O-CB 3.43Å; T233-S237 PolarHBondContact O-N 3.29Å; T233-S237 PolarHBondContact O-OG 3.35Å; T233-S260 VanDerWaalsContact CB-OG 3.3Å; T233-S260 WeakPolarHBondContact CB-OG 3.22Å; T233-S260 WeakPolarHBondContact OG1-CB 3.46Å; T233-S260 PolarHBondContact OG1-OG 3.21Å
234	M	93.4	Very high	88.6	Confident	3 Å²	3	33.1 Å²	33.1	2%	0.015	18%	0.18	C	C	.	.	H	α-helix	trans	-59.4	-45.8	177.8	-73.8	-171.9	-74.1	0	0	111.5	A230 L231 L232 S237 G238 W261 V264 M362	A230-M234 WeakPolarHBondContact O-CE 3.39Å; A230-M234 WeakPolarHBondContact O-CG 3.12Å; A230-M234 PolarHBondContact O-N 3.25Å; L231-M234 HydrophobicContact CD2-CE 3.67Å; L231-M234 HydrophobicContact CG-CE 4.4Å; L231-M234 PolarHBondContact O-N 3.38Å; L232-M234 PolarHBondContact O-N 2.79Å; M234-S237 PolarHBondContact O-OG 2.53Å; M234-G238 PolarHBondContact O-N 2.8Å; M234-W261 HydrophobicContact SD-CB 4.19Å; M234-W261 HydrophobicContact SD-CD2 3.95Å; M234-W261 HydrophobicContact SD-CG 3.59Å; M234-W261 VanDerWaalsContact SD-CG 3.59Å; M234-V264 HydrophobicContact CE-CB 4.38Å; M234-V264 HydrophobicContact CE-CG2 3.57Å; M234-M362 HydrophobicContact CE-CE 3.84Å; M234-M362 HydrophobicContact CE-SD 3.68Å; M234-M362 HydrophobicContact SD-CE 4.12Å
235	L	90.3	Very high	88.1	Confident	47 Å²	47	34.7 Å²	34.7	25%	0.246	18%	0.183	C	C	.	.	H	α-helix	trans	-66.8	-51.1	-179.7	-66.9	175.9	0	0	0	112	L231 L232 T233 G238 T239 V361 L364 L368	L231-L235 WeakPolarHBondContact O-CG 3.34Å; L231-L235 PolarHBondContact O-N 2.89Å; L231-L235 VanDerWaalsContact O-N 3.1Å; L232-L235 PolarHBondContact O-N 3.45Å; T233-L235 VanDerWaalsContact C-N 3.33Å; T233-L235 PolarHBondContact O-N 2.97Å; L235-G238 PolarHBondContact O-N 3.01Å; L235-T239 WeakPolarHBondContact O-CG2 3.47Å; L235-T239 PolarHBondContact O-N 3.22Å; L235-T239 PolarHBondContact O-OG1 3.39Å; L235-T239 VanDerWaalsContact O-OG1 3.1Å; L235-V361 HydrophobicContact CD1-CG1 4.15Å; L235-V361 HydrophobicContact CD2-CG1 4.49Å; L235-L364 HydrophobicContact CD2-CD2 3.33Å; L235-L368 HydrophobicContact CD2-CD1 4.03Å
236	I	87.3	Confident	87.7	Confident	52 Å²	52	31.3 Å²	31.3	27%	0.267	17%	0.17	S	C	.	.	H	α-helix	trans	-64.3	-44.6	-177.8	-65.8	166.6	0	0	0	110.9	F173 L232 T239 Y240 I479	F173-I236 HydrophobicContact CD2-CD1 4.15Å; F173-I236 HydrophobicContact CE2-CD1 4.27Å; L232-I236 HydrophobicContact CB-CD1 4.43Å; L232-I236 WeakPolarHBondContact O-CB 3.13Å; L232-I236 VanDerWaalsContact O-CG1 3.23Å; L232-I236 WeakPolarHBondContact O-CG1 3.37Å; L232-I236 PolarHBondContact O-N 2.95Å; I236-T239 PolarHBondContact O-OG1 3.47Å; I236-T239 VanDerWaalsContact O-OG1 3.1Å; I236-Y240 WeakPolarHBondContact O-CB 3.49Å; I236-Y240 PolarHBondContact O-N 2.91Å; I236-I479 HydrophobicContact CD1-CD1 4.43Å; I236-I479 HydrophobicContact CG2-CD1 4.2Å
237	S	86.9	Confident	87.4	Confident	6 Å²	6	31.2 Å²	31.2	4%	0.042	17%	0.169	C	C	.	.	H	α-helix	trans	-67.7	-39	178.5	61.7	0	0	0	0	111.9	T233 M234 S241 L253 S257	T233-S237 WeakPolarHBondContact O-CB 3.43Å; T233-S237 PolarHBondContact O-N 3.29Å; T233-S237 PolarHBondContact O-OG 3.35Å; M234-S237 PolarHBondContact O-OG 2.53Å; S237-S241 VanDerWaalsContact O-CB 3.27Å; S237-S241 WeakPolarHBondContact O-CB 3.28Å; S237-S241 PolarHBondContact O-N 3.5Å; S237-L253 WeakPolarHBondContact CB-O 3.38Å; S237-S257 WeakPolarHBondContact OG-CA 3.46Å; S237-S257 WeakPolarHBondContact OG-CB 3.08Å; S237-S257 PolarHBondContact OG-N 3.38Å
238	G	87.4	Confident	87.3	Confident	1 Å²	1	30.7 Å²	30.7	1%	0.01	17%	0.166	C	C	.	.	H	α-helix	trans	-59.7	-49.8	174.4	0	0	0	0	0	112.4	M234 L235 S241	M234-G238 PolarHBondContact O-N 2.8Å; L235-G238 PolarHBondContact O-N 3.01Å; G238-S241 PolarHBondContact O-OG 3.06Å
239	T	84.6	Confident	87.1	Confident	51 Å²	51	30.7 Å²	30.7	31%	0.313	16%	0.159	S	C	.	.	H	α-helix	trans	-69.5	-43	179.8	55.4	0	0	0	0	112.6	L235 I236 S241 L242 L368	L235-T239 WeakPolarHBondContact O-CG2 3.47Å; L235-T239 PolarHBondContact O-N 3.22Å; L235-T239 PolarHBondContact O-OG1 3.39Å; L235-T239 VanDerWaalsContact O-OG1 3.1Å; I236-T239 PolarHBondContact O-OG1 3.47Å; I236-T239 VanDerWaalsContact O-OG1 3.1Å; T239-S241 VanDerWaalsContact C-N 3.28Å; T239-S241 PolarHBondContact O-N 3Å; T239-L242 WeakPolarHBondContact O-CB 3.29Å; T239-L242 PolarHBondContact O-N 3.44Å; T239-L242 VanDerWaalsContact O-N 3.14Å; T239-L368 HydrophobicContact CG2-CD1 4.23Å; T239-L368 HydrophobicContact CG2-CD2 4.2Å
240	Y	84.1	Confident	86.9	Confident	85 Å²	85	30.1 Å²	30.1	33%	0.333	16%	0.155	S	C	.	.	H	α-helix	trans	-65.3	-33.2	179.8	-169.7	-127.2	0	0	0	112	L180 I236 L242 I243 C244 L253 M472	L180-Y240 HydrophobicContact CD1-CE1 4.03Å; I236-Y240 WeakPolarHBondContact O-CB 3.49Å; I236-Y240 PolarHBondContact O-N 2.91Å; Y240-L242 PolarHBondContact O-N 3.32Å; Y240-L242 VanDerWaalsContact O-N 3.1Å; Y240-I243 PolarHBondContact O-N 3.17Å; Y240-C244 VanDerWaalsContact CD1-SG 3.51Å; Y240-C244 WeakPolarHBondContact CE1-SG 3.44Å; Y240-C244 VanDerWaalsContact CZ-SG 3.52Å; Y240-C244 PolarHBondContact O-N 2.94Å; Y240-C244 PolarHBondContact O-SG 3.38Å; Y240-L253 HydrophobicContact CD1-CD1 3.28Å; Y240-L253 HydrophobicContact CD1-CD2 3.72Å; Y240-L253 HydrophobicContact CD1-CG 4.12Å; Y240-L253 HydrophobicContact CE1-CD1 3.92Å; Y240-L253 HydrophobicContact CE1-CD2 4.5Å; Y240-L253 HydrophobicContact CG-CD1 4.02Å; Y240-M472 HydrophobicContact CD2-CE 3.82Å
241	S	83.4	Confident	86.7	Confident	1 Å²	1	30.1 Å²	30.1	1%	0.007	16%	0.155	C	C	.	.	T	Hydrogen-bonded Turn	trans	-61.4	-19.7	175.8	77.6	0	0	0	0	114.1	S237 G238 T239 S250 Y372 R375	S237-S241 VanDerWaalsContact O-CB 3.27Å; S237-S241 WeakPolarHBondContact O-CB 3.28Å; S237-S241 PolarHBondContact O-N 3.5Å; G238-S241 PolarHBondContact O-OG 3.06Å; T239-S241 VanDerWaalsContact C-N 3.28Å; T239-S241 PolarHBondContact O-N 3Å; S241-S250 PolarHBondContact O-OG 3.02Å; S241-Y372 WeakPolarHBondContact OG-CB 3.35Å; S241-Y372 WeakPolarHBondContact OG-CD1 3.47Å; S241-R375 PolarHBondContact O-NH1 3.22Å
242	L	82.7	Confident	86.5	Confident	23 Å²	23	28.8 Å²	28.8	12%	0.12	15%	0.148	C	C	.	.	T	Hydrogen-bonded Turn	trans	-81.2	-15.4	175.7	-59.7	177.9	0	0	0	113.5	T239 Y240 L368 V371 R375	T239-L242 WeakPolarHBondContact O-CB 3.29Å; T239-L242 PolarHBondContact O-N 3.44Å; T239-L242 VanDerWaalsContact O-N 3.14Å; Y240-L242 PolarHBondContact O-N 3.32Å; Y240-L242 VanDerWaalsContact O-N 3.1Å; L242-L368 HydrophobicContact CD1-CD2 4.43Å; L242-V371 HydrophobicContact CD1-CG1 4.02Å; L242-V371 HydrophobicContact CD2-CB 4.38Å; L242-V371 HydrophobicContact CD2-CG1 3.62Å; L242-V371 HydrophobicContact CG-CG1 4.49Å; L242-R375 PolarHBondContact O-NE 2.94Å; L242-R375 VanDerWaalsContact O-NE 3.13Å; L242-R375 PolarHBondContact O-NH1 2.89Å; L242-R375 VanDerWaalsContact O-NH1 3.13Å; L242-R375 PolarHBondContact O-NH2 3.4Å
243	I	79	Confident	86.5	Confident	52 Å²	52	25.5 Å²	25.5	27%	0.267	13%	0.131	S	C	.	.	T	Hydrogen-bonded Turn	trans	-110.9	-29.7	-175.5	-63.7	159	0	0	0	111	Y240 N245 M472	Y240-I243 PolarHBondContact O-N 3.17Å; I243-N245 PolarHBondContact O-N 2.89Å; I243-N245 PolarHBondContact O-OD1 3.38Å; I243-M472 HydrophobicContact CD1-CB 4.05Å; I243-M472 HydrophobicContact CD1-CE 3.56Å; I243-M472 HydrophobicContact CD1-CG 3.36Å; I243-M472 HydrophobicContact CD1-SD 3.29Å; I243-M472 WeakPolarHBondContact CD1-SD 3.32Å
244	C	77.7	Confident	86.6	Confident	7 Å²	7	25.2 Å²	25.2	5%	0.047	13%	0.129	C	C	.	.			trans	-54.7	132.4	-180	-72.4	0	0	0	0	112.6	Y240 L253 R375	Y240-C244 VanDerWaalsContact CD1-SG 3.51Å; Y240-C244 WeakPolarHBondContact CE1-SG 3.44Å; Y240-C244 VanDerWaalsContact CZ-SG 3.52Å; Y240-C244 PolarHBondContact O-N 2.94Å; Y240-C244 PolarHBondContact O-SG 3.38Å; C244-L253 HydrophobicContact CB-CD1 4.32Å; C244-L253 WeakPolarHBondContact SG-CD1 3.29Å; C244-R375 VanDerWaalsContact O-CZ 3.31Å; C244-R375 PolarHBondContact O-NH1 3.41Å; C244-R375 PolarHBondContact O-NH2 3.47Å
245	N	81	Confident	86.6	Confident	98 Å²	98	25 Å²	25	52%	0.524	13%	0.128	S	C	.	.			trans	-98.2	-6.3	179.2	-70.2	-23.5	0	0	0	113.3	I243 K304 V305	I243-N245 PolarHBondContact O-N 2.89Å; I243-N245 PolarHBondContact O-OD1 3.38Å; N245-K304 CarbonylContact O-C 3.54Å; N245-K304 VanDerWaalsContact O-CA 3.32Å; N245-K304 WeakPolarHBondContact O-CA 3.26Å; N245-V305 VanDerWaalsContact O-CG2 3.29Å; N245-V305 WeakPolarHBondContact O-CG2 3.25Å; N245-V305 PolarHBondContact O-N 3.33Å
246	D	84.4	Confident	86.6	Confident	42 Å²	42	23 Å²	23	23%	0.225	12%	0.118	C	C	.	.	B	Isolated β-bridge	trans	-97.7	126.1	174.7	-73.2	-19	0	0	0	109.7	K248 Q249 S250 K304	D246-K248 PolarHBondContact O-N 3.34Å; D246-Q249 HydrophobicContact CB-CB 4.01Å; D246-Q249 HydrophobicContact CB-CG 3.89Å; D246-Q249 PolarHBondContact O-N 3Å; D246-S250 PolarHBondContact O-N 3.39Å; D246-K304 WeakPolarHBondContact OD1-CG 3.33Å
247	M	85	Confident	86.9	Confident	4 Å²	4	20.8 Å²	20.8	2%	0.02	11%	0.107	C	C	.	.	H	α-helix	trans	-60.4	-45.8	-176.2	-67.6	-65.3	-78.4	0	0	111.5	Q249 S250 M251 V292 Q303 V305 V308 L376 L379 F380	M247-Q249 PolarHBondContact O-N 3.2Å; M247-S250 PolarHBondContact O-N 3.27Å; M247-M251 WeakPolarHBondContact O-CG 3.29Å; M247-M251 PolarHBondContact O-N 3.39Å; M247-M251 VanDerWaalsContact O-N 3.07Å; M247-V292 HydrophobicContact CB-CG1 4.29Å; M247-Q303 PolarHBondContact N-O 2.66Å; M247-V305 HydrophobicContact SD-CG2 3.91Å; M247-V308 HydrophobicContact CG-CG2 4.06Å; M247-L376 HydrophobicContact CE-CD2 4.37Å; M247-L376 HydrophobicContact SD-CD2 4.48Å; M247-L379 HydrophobicContact CE-CB 4.19Å; M247-L379 HydrophobicContact SD-CB 4.1Å; M247-L379 HydrophobicContact SD-CD1 4.17Å; M247-F380 HydrophobicContact CE-CD1 3.91Å; M247-F380 HydrophobicContact CE-CD2 4.21Å; M247-F380 HydrophobicContact CE-CE1 3.61Å; M247-F380 HydrophobicContact CE-CE2 3.9Å; M247-F380 HydrophobicContact CE-CG 4.22Å; M247-F380 HydrophobicContact CE-CZ 3.61Å
248	K	90.8	Very high	87.2	Confident	3 Å²	3	20.5 Å²	20.5	1%	0.013	11%	0.105	C	C	.	.	H	α-helix	trans	-62.4	-38.9	177.9	-72.7	-168.3	-77.6	176.2	0	112.9	M183 A185 T187 D246 M251 A252 V292 I296	M183-K248 HydrophobicContact CB-CB 4.04Å; M183-K248 HydrophobicContact CG-CB 4.37Å; M183-K248 WeakPolarHBondContact O-CE 3.34Å; M183-K248 PolarHBondContact O-NZ 3.38Å; M183-K248 HydrophobicContact SD-CB 4.29Å; A185-K248 PolarHBondContact O-NZ 3.27Å; A185-K248 VanDerWaalsContact O-NZ 3.14Å; T187-K248 HydrophobicContact CG2-CD 3.91Å; D246-K248 PolarHBondContact O-N 3.34Å; K248-M251 WeakPolarHBondContact O-CB 3.49Å; K248-M251 PolarHBondContact O-N 3.3Å; K248-A252 PolarHBondContact O-N 2.89Å; K248-V292 HydrophobicContact CG-CG1 4.12Å; K248-I296 HydrophobicContact CD-CD1 4.23Å; K248-I296 HydrophobicContact CG-CD1 3.96Å
249	Q	88.2	Confident	87.5	Confident	43 Å²	43	20.6 Å²	20.6	20%	0.201	11%	0.105	C	C	.	.	H	α-helix	trans	-69.8	-40	178.8	-67.9	-177.5	-15.6	0	0	111.8	L180 M183 D246 M247 M251 A252 L253	L180-Q249 HydrophobicContact CD2-CB 4.41Å; M183-Q249 HydrophobicContact CB-CG 4.47Å; D246-Q249 HydrophobicContact CB-CB 4.01Å; D246-Q249 HydrophobicContact CB-CG 3.89Å; D246-Q249 PolarHBondContact O-N 3Å; M247-Q249 PolarHBondContact O-N 3.2Å; Q249-M251 VanDerWaalsContact C-N 3.26Å; Q249-M251 PolarHBondContact O-N 3.37Å; Q249-A252 WeakPolarHBondContact O-CB 3.49Å; Q249-A252 PolarHBondContact O-N 3.23Å; Q249-A252 VanDerWaalsContact O-N 3.13Å; Q249-L253 WeakPolarHBondContact O-CG 3.29Å; Q249-L253 PolarHBondContact O-N 2.9Å
250	S	88.2	Confident	88	Confident	2 Å²	2	18.2 Å²	18.2	1%	0.014	9%	0.091	C	C	.	.	H	α-helix	trans	-61.3	-37.6	173.3	-173.7	0	0	0	0	111.7	S241 D246 M247 L253 S254	S241-S250 PolarHBondContact O-OG 3.02Å; D246-S250 PolarHBondContact O-N 3.39Å; M247-S250 PolarHBondContact O-N 3.27Å; S250-L253 PolarHBondContact O-N 3.11Å; S250-S254 PolarHBondContact O-N 3.49Å; S250-S254 VanDerWaalsContact O-N 3.13Å; S250-S254 PolarHBondContact O-OG 3.39Å; S250-S254 VanDerWaalsContact O-OG 3.06Å
251	M	91.4	Very high	88.5	Confident	0 Å²	0	14.2 Å²	14.2	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-65.9	-35.8	172.7	-67.9	-50.9	-54.6	0	0	113.8	M247 K248 Q249 S254 T255 K285 V288 F289 V292 L329 L376	M247-M251 WeakPolarHBondContact O-CG 3.29Å; M247-M251 PolarHBondContact O-N 3.39Å; M247-M251 VanDerWaalsContact O-N 3.07Å; K248-M251 WeakPolarHBondContact O-CB 3.49Å; K248-M251 PolarHBondContact O-N 3.3Å; Q249-M251 VanDerWaalsContact C-N 3.26Å; Q249-M251 PolarHBondContact O-N 3.37Å; M251-S254 WeakPolarHBondContact CA-OG 3.35Å; M251-S254 PolarHBondContact O-N 3.09Å; M251-S254 PolarHBondContact O-OG 2.98Å; M251-T255 PolarHBondContact O-N 2.88Å; M251-T255 VanDerWaalsContact O-N 3.16Å; M251-K285 HydrophobicContact CE-CD 4.29Å; M251-K285 PolarHBondContact O-NZ 3.23Å; M251-V288 HydrophobicContact CE-CB 3.6Å; M251-V288 HydrophobicContact CE-CG1 3.16Å; M251-V288 HydrophobicContact CE-CG2 4.32Å; M251-V288 HydrophobicContact SD-CG1 3.78Å; M251-F289 HydrophobicContact CB-CD1 4.42Å; M251-F289 HydrophobicContact CB-CE1 3.69Å; M251-F289 HydrophobicContact CB-CZ 3.82Å; M251-V292 HydrophobicContact CG-CG2 3.93Å; M251-L329 HydrophobicContact CE-CD1 4.08Å; M251-L376 HydrophobicContact SD-CD1 3.68Å; M251-L376 HydrophobicContact SD-CD2 4.3Å
252	A	90.5	Very high	89	Confident	0 Å²	0	14.2 Å²	14.2	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-66.5	-40.2	173.8	0	0	0	0	0	112.1	L179 L180 M183 K248 Q249 S254 T255 C256	L179-A252 HydrophobicContact CD2-CB 4.02Å; L179-A252 WeakPolarHBondContact CD2-O 3.42Å; L179-A252 HydrophobicContact CG-CB 4.41Å; L180-A252 HydrophobicContact CD2-CB 4.04Å; M183-A252 HydrophobicContact CE-CB 3.43Å; M183-A252 VanDerWaalsContact CE-CB 3.43Å; M183-A252 HydrophobicContact CG-CB 3.8Å; M183-A252 HydrophobicContact SD-CB 4.17Å; K248-A252 PolarHBondContact O-N 2.89Å; Q249-A252 WeakPolarHBondContact O-CB 3.49Å; Q249-A252 PolarHBondContact O-N 3.23Å; Q249-A252 VanDerWaalsContact O-N 3.13Å; A252-S254 VanDerWaalsContact C-N 3.28Å; A252-S254 PolarHBondContact O-N 2.92Å; A252-T255 PolarHBondContact O-N 3.29Å; A252-T255 PolarHBondContact O-OG1 3.28Å; A252-C256 PolarHBondContact O-N 3.48Å
253	L	90.2	Very high	89.6	Confident	9 Å²	9	13.8 Å²	13.8	5%	0.047	7%	0.073	C	C	.	.	H	α-helix	trans	-67.7	-34.5	177.9	-68.1	164	0	0	0	111.9	L180 S237 Y240 C244 Q249 S250 T255 C256 S257	L180-L253 HydrophobicContact CD1-CD2 4.33Å; L180-L253 HydrophobicContact CD2-CD1 4.4Å; L180-L253 HydrophobicContact CD2-CD2 3.78Å; L180-L253 HydrophobicContact CD2-CG 3.78Å; S237-L253 WeakPolarHBondContact CB-O 3.38Å; Y240-L253 HydrophobicContact CD1-CD1 3.28Å; Y240-L253 HydrophobicContact CD1-CD2 3.72Å; Y240-L253 HydrophobicContact CD1-CG 4.12Å; Y240-L253 HydrophobicContact CE1-CD1 3.92Å; Y240-L253 HydrophobicContact CE1-CD2 4.5Å; Y240-L253 HydrophobicContact CG-CD1 4.02Å; C244-L253 HydrophobicContact CB-CD1 4.32Å; C244-L253 WeakPolarHBondContact SG-CD1 3.29Å; Q249-L253 WeakPolarHBondContact O-CG 3.29Å; Q249-L253 PolarHBondContact O-N 2.9Å; S250-L253 PolarHBondContact O-N 3.11Å; L253-T255 VanDerWaalsContact C-N 3.27Å; L253-T255 PolarHBondContact O-N 3.42Å; L253-C256 PolarHBondContact O-N 3.21Å; L253-S257 PolarHBondContact O-N 3.41Å; L253-S257 PolarHBondContact O-OG 3.01Å
254	S	92.4	Very high	90.3	Very high	0 Å²	0	11.3 Å²	11.3	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-73	-15.4	171.3	51.8	0	0	0	0	113.4	S250 M251 A252 S257 N258 K285 Y372	S250-S254 PolarHBondContact O-N 3.49Å; S250-S254 VanDerWaalsContact O-N 3.13Å; S250-S254 PolarHBondContact O-OG 3.39Å; S250-S254 VanDerWaalsContact O-OG 3.06Å; M251-S254 WeakPolarHBondContact CA-OG 3.35Å; M251-S254 PolarHBondContact O-N 3.09Å; M251-S254 PolarHBondContact O-OG 2.98Å; A252-S254 VanDerWaalsContact C-N 3.28Å; A252-S254 PolarHBondContact O-N 2.92Å; S254-S257 WeakPolarHBondContact CA-OG 3.26Å; S254-S257 PolarHBondContact O-OG 3.33Å; S254-N258 PolarHBondContact O-ND2 2.86Å; S254-K285 VanDerWaalsContact CB-NZ 3.3Å; S254-K285 PolarHBondContact O-NZ 2.98Å; S254-K285 PolarHBondContact OG-NZ 3.33Å; S254-Y372 VanDerWaalsContact CB-CE2 3.45Å
255	T	92.9	Very high	91	Very high	0 Å²	0	11 Å²	11	0%	0	6%	0.058	C	C	.	.	H	α-helix	trans	-78.1	-47.4	164.5	58.8	0	0	0	0	110.2	L179 M251 A252 L253 S257 N258 I259 K285 F289	L179-T255 WeakPolarHBondContact CD2-OG1 3.39Å; M251-T255 PolarHBondContact O-N 2.88Å; M251-T255 VanDerWaalsContact O-N 3.16Å; A252-T255 PolarHBondContact O-N 3.29Å; A252-T255 PolarHBondContact O-OG1 3.28Å; L253-T255 VanDerWaalsContact C-N 3.27Å; L253-T255 PolarHBondContact O-N 3.42Å; T255-S257 VanDerWaalsContact C-N 3.28Å; T255-S257 PolarHBondContact O-N 2.76Å; T255-N258 PolarHBondContact O-N 3.29Å; T255-N258 VanDerWaalsContact O-N 3.11Å; T255-I259 WeakPolarHBondContact O-CD1 3.46Å; T255-I259 PolarHBondContact O-N 3.39Å; T255-K285 HydrophobicContact CG2-CD 3.54Å; T255-K285 VanDerWaalsContact CG2-CE 3.42Å; T255-K285 HydrophobicContact CG2-CG 3.87Å; T255-F289 HydrophobicContact CG2-CE2 4.19Å
256	C	91.7	Very high	91.5	Very high	4 Å²	4	6.3 Å²	6.3	3%	0.027	3%	0.033	C	C	.	.	H	α-helix	trans	-51.1	-46.6	176.3	-68.7	0	0	0	0	112.5	L179 A252 L253 S260	L179-C256 WeakPolarHBondContact CD2-SG 3.44Å; A252-C256 PolarHBondContact O-N 3.48Å; L253-C256 PolarHBondContact O-N 3.21Å; C256-S260 VanDerWaalsContact O-CB 3.31Å; C256-S260 WeakPolarHBondContact O-CB 3.39Å; C256-S260 PolarHBondContact O-N 3.19Å; C256-S260 PolarHBondContact O-OG 3.41Å
257	S	92.8	Very high	91.8	Very high	5 Å²	5	5 Å²	5	4%	0.035	3%	0.026	C	C	.	.	H	α-helix	trans	-62.7	-49.3	177.5	50.7	0	0	0	0	112.2	S237 L253 S254 T255 I259 S260 W261 Y372	S237-S257 WeakPolarHBondContact OG-CA 3.46Å; S237-S257 WeakPolarHBondContact OG-CB 3.08Å; S237-S257 PolarHBondContact OG-N 3.38Å; L253-S257 PolarHBondContact O-N 3.41Å; L253-S257 PolarHBondContact O-OG 3.01Å; S254-S257 WeakPolarHBondContact CA-OG 3.26Å; S254-S257 PolarHBondContact O-OG 3.33Å; T255-S257 VanDerWaalsContact C-N 3.28Å; T255-S257 PolarHBondContact O-N 2.76Å; S257-I259 PolarHBondContact O-N 3.12Å; S257-S260 WeakPolarHBondContact O-CB 3.43Å; S257-S260 PolarHBondContact O-N 3.47Å; S257-W261 VanDerWaalsContact O-CD1 3.26Å; S257-W261 PolarHBondContact O-N 3.43Å; S257-Y372 PolarHBondContact OG-OH 3.02Å
258	N	93.8	Very high	92	Very high	0 Å²	0	6.7 Å²	6.7	0%	0	4%	0.035	C	C	.	.	H	α-helix	trans	-68.7	-33.3	-177.4	-76.7	-41.5	0	0	0	113.8	S254 T255 W261 V262 Q277 H281 K341	S254-N258 PolarHBondContact O-ND2 2.86Å; T255-N258 PolarHBondContact O-N 3.29Å; T255-N258 VanDerWaalsContact O-N 3.11Å; N258-W261 WeakPolarHBondContact O-CB 3.28Å; N258-W261 PolarHBondContact O-N 3.01Å; N258-V262 WeakPolarHBondContact O-CG2 3.29Å; N258-V262 PolarHBondContact O-N 2.85Å; N258-Q277 PolarHBondContact O-NE2 3.14Å; N258-H281 WeakPolarHBondContact CB-CD2 3.47Å; N258-K341 PolarHBondContact OD1-NZ 3.01Å
259	I	93.9	Very high	91.8	Very high	4 Å²	4	8.5 Å²	8.5	2%	0.021	6%	0.055	C	C	.	.	H	α-helix	trans	-70.3	-36.4	171.9	-75.3	121.3	0	0	0	111.2	V199 M203 T255 S257 W261 V262 V263 H281	V199-I259 HydrophobicContact CB-CD1 4.08Å; V199-I259 HydrophobicContact CG1-CB 4.18Å; V199-I259 HydrophobicContact CG1-CD1 3.17Å; V199-I259 HydrophobicContact CG1-CG1 3.63Å; V199-I259 HydrophobicContact CG1-CG2 3.96Å; M203-I259 HydrophobicContact CG-CG2 4.04Å; M203-I259 HydrophobicContact SD-CG2 4.04Å; T255-I259 WeakPolarHBondContact O-CD1 3.46Å; T255-I259 PolarHBondContact O-N 3.39Å; S257-I259 PolarHBondContact O-N 3.12Å; I259-W261 VanDerWaalsContact C-N 3.27Å; I259-W261 PolarHBondContact O-N 3.29Å; I259-V262 WeakPolarHBondContact O-CA 3.49Å; I259-V262 VanDerWaalsContact O-CB 3.32Å; I259-V262 WeakPolarHBondContact O-CB 3.23Å; I259-V262 PolarHBondContact O-N 2.9Å; I259-V263 WeakPolarHBondContact O-CG2 3.33Å; I259-V263 PolarHBondContact O-N 2.93Å; I259-H281 VanDerWaalsContact CD1-CE1 3.46Å; I259-H281 WeakPolarHBondContact CD1-CE1 3.46Å
260	S	94.5	Very high	91.8	Very high	0 Å²	0	9.2 Å²	9.2	0%	0	6%	0.058	C	C	.	.	H	α-helix	trans	-64.7	-33.1	174.3	-58.1	0	0	0	0	112	L172 T233 C256 S257 V262 V263 V264	L172-S260 WeakPolarHBondContact CD2-OG 3.3Å; T233-S260 VanDerWaalsContact CB-OG 3.3Å; T233-S260 WeakPolarHBondContact CB-OG 3.22Å; T233-S260 WeakPolarHBondContact OG1-CB 3.46Å; T233-S260 PolarHBondContact OG1-OG 3.21Å; C256-S260 VanDerWaalsContact O-CB 3.31Å; C256-S260 WeakPolarHBondContact O-CB 3.39Å; C256-S260 PolarHBondContact O-N 3.19Å; C256-S260 PolarHBondContact O-OG 3.41Å; S257-S260 WeakPolarHBondContact O-CB 3.43Å; S257-S260 PolarHBondContact O-N 3.47Å; S260-V262 VanDerWaalsContact C-N 3.32Å; S260-V262 PolarHBondContact O-N 3.43Å; S260-V263 PolarHBondContact O-N 3.43Å; S260-V264 WeakPolarHBondContact O-CG2 3.47Å; S260-V264 PolarHBondContact O-N 3.41Å
261	W	94.3	Very high	91.8	Very high	2 Å²	2	12.2 Å²	12.2	1%	0.008	7%	0.069	C	C	.	.	H	α-helix	trans	-58.7	-44.4	167.6	-85.6	92	0	0	0	111.7	M234 S257 N258 I259 V263 V264 M265 K341 F344 I345 M362 C365 V366	M234-W261 HydrophobicContact SD-CB 4.19Å; M234-W261 HydrophobicContact SD-CD2 3.95Å; M234-W261 HydrophobicContact SD-CG 3.59Å; M234-W261 VanDerWaalsContact SD-CG 3.59Å; S257-W261 VanDerWaalsContact O-CD1 3.26Å; S257-W261 PolarHBondContact O-N 3.43Å; N258-W261 WeakPolarHBondContact O-CB 3.28Å; N258-W261 PolarHBondContact O-N 3.01Å; I259-W261 VanDerWaalsContact C-N 3.27Å; I259-W261 PolarHBondContact O-N 3.29Å; W261-V263 VanDerWaalsContact C-N 3.34Å; W261-V263 PolarHBondContact O-N 3.44Å; W261-V264 PolarHBondContact O-N 3.4Å; W261-M265 HydrophobicContact CE3-CE 4.18Å; W261-M265 WeakPolarHBondContact O-CG 3.44Å; W261-M265 PolarHBondContact O-N 3.31Å; W261-K341 HydrophobicContact CE3-CG 4.45Å; W261-F344 HydrophobicContact CE3-CD1 4.26Å; W261-F344 HydrophobicContact CE3-CE1 4.43Å; W261-F344 AromaticContact CZ3-CD1 3.99Å; W261-F344 HydrophobicContact CZ3-CD1 3.99Å; W261-F344 HydrophobicContact CZ3-CE1 4.31Å; W261-I345 HydrophobicContact CH2-CD1 4.15Å; W261-I345 HydrophobicContact CH2-CG1 4.47Å; W261-I345 HydrophobicContact CZ3-CD1 4.43Å; W261-I345 HydrophobicContact CZ3-CG1 4.4Å; W261-M362 HydrophobicContact CD2-CE 3.64Å; W261-M362 HydrophobicContact CE3-CE 3.2Å; W261-M362 HydrophobicContact CH2-CB 3.89Å; W261-M362 HydrophobicContact CH2-CE 3.42Å; W261-M362 VanDerWaalsContact CH2-CE 3.42Å; W261-M362 HydrophobicContact CH2-SD 4.48Å; W261-M362 HydrophobicContact CZ2-CE 3.84Å; W261-M362 WeakPolarHBondContact CZ2-O 3.33Å; W261-M362 HydrophobicContact CZ3-CB 4.44Å; W261-M362 HydrophobicContact CZ3-CE 3.1Å; W261-C365 HydrophobicContact CZ2-CB 3.71Å; W261-V366 HydrophobicContact CH2-CG2 3.53Å; W261-V366 HydrophobicContact CZ2-CG2 3.55Å
262	V	94.8	Very high	91.6	Very high	1 Å²	1	16.8 Å²	16.8	1%	0.006	9%	0.094	C	C	.	.	H	α-helix	trans	-61.9	-42.1	177.5	178.3	0	0	0	0	110.8	M203 N258 I259 S260 V264 M265 M266 G274 Q277 L278	M203-V262 HydrophobicContact CE-CB 4.2Å; M203-V262 HydrophobicContact CE-CG1 3.68Å; M203-V262 HydrophobicContact CG-CG1 4.47Å; N258-V262 WeakPolarHBondContact O-CG2 3.29Å; N258-V262 PolarHBondContact O-N 2.85Å; I259-V262 WeakPolarHBondContact O-CA 3.49Å; I259-V262 VanDerWaalsContact O-CB 3.32Å; I259-V262 WeakPolarHBondContact O-CB 3.23Å; I259-V262 PolarHBondContact O-N 2.9Å; S260-V262 VanDerWaalsContact C-N 3.32Å; S260-V262 PolarHBondContact O-N 3.43Å; V262-V264 VanDerWaalsContact C-N 3.34Å; V262-V264 PolarHBondContact O-N 2.96Å; V262-M265 PolarHBondContact O-N 3.02Å; V262-M266 HydrophobicContact CG1-CE 3.28Å; V262-M266 HydrophobicContact CG1-SD 4.16Å; V262-M266 VanDerWaalsContact O-CG 3.31Å; V262-M266 WeakPolarHBondContact O-CG 3.31Å; V262-M266 PolarHBondContact O-N 3.46Å; V262-G274 WeakPolarHBondContact CG1-O 3.45Å; V262-Q277 HydrophobicContact CG2-CB 4.08Å; V262-Q277 HydrophobicContact CG2-CG 3.77Å; V262-L278 HydrophobicContact CG1-CB 4.3Å; V262-L278 HydrophobicContact CG1-CD1 4.31Å; V262-L278 HydrophobicContact CG2-CB 4.31Å
263	V	94.3	Very high	91.4	Very high	13 Å²	13	17 Å²	17	8%	0.079	10%	0.095	C	C	.	.	H	α-helix	trans	-59.3	-45.4	175	176.1	0	0	0	0	111	L172 M203 A230 I259 S260 W261 M265 M266 L267	L172-V263 HydrophobicContact CD1-CG1 4.29Å; L172-V263 HydrophobicContact CD1-CG2 4.07Å; L172-V263 HydrophobicContact CD2-CG2 4.13Å; M203-V263 HydrophobicContact CE-CB 4.05Å; M203-V263 HydrophobicContact CE-CG2 3.3Å; M203-V263 HydrophobicContact SD-CG2 3.39Å; M203-V263 WeakPolarHBondContact SD-CG2 3.42Å; A230-V263 HydrophobicContact CB-CB 4.22Å; A230-V263 HydrophobicContact CB-CG1 3.85Å; I259-V263 WeakPolarHBondContact O-CG2 3.33Å; I259-V263 PolarHBondContact O-N 2.93Å; S260-V263 PolarHBondContact O-N 3.43Å; W261-V263 VanDerWaalsContact C-N 3.34Å; W261-V263 PolarHBondContact O-N 3.44Å; V263-M265 PolarHBondContact O-N 3.34Å; V263-M266 PolarHBondContact O-N 2.87Å; V263-L267 HydrophobicContact CG1-CD1 3.88Å; V263-L267 HydrophobicContact CG1-CG 4.26Å; V263-L267 VanDerWaalsContact O-CG 3.31Å; V263-L267 WeakPolarHBondContact O-CG 3.36Å; V263-L267 PolarHBondContact O-N 2.92Å
264	V	93.8	Very high	91.5	Very high	0 Å²	0	16.6 Å²	16.6	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-63.6	-39.9	178.5	166.5	0	0	0	0	112.2	M227 A230 M234 S260 W261 V262 L267 L268 F344 M362	M227-V264 HydrophobicContact CE-CB 4.05Å; M227-V264 HydrophobicContact CE-CG1 3.32Å; M227-V264 HydrophobicContact CE-CG2 3.62Å; M227-V264 HydrophobicContact SD-CB 4.4Å; M227-V264 HydrophobicContact SD-CG1 4.05Å; M227-V264 HydrophobicContact SD-CG2 3.98Å; A230-V264 HydrophobicContact CB-CG2 3.65Å; M234-V264 HydrophobicContact CE-CB 4.38Å; M234-V264 HydrophobicContact CE-CG2 3.57Å; S260-V264 WeakPolarHBondContact O-CG2 3.47Å; S260-V264 PolarHBondContact O-N 3.41Å; W261-V264 PolarHBondContact O-N 3.4Å; V262-V264 VanDerWaalsContact C-N 3.34Å; V262-V264 PolarHBondContact O-N 2.96Å; V264-L267 PolarHBondContact O-N 3.48Å; V264-L268 HydrophobicContact CG1-CD1 4.29Å; V264-L268 WeakPolarHBondContact O-CG 3.31Å; V264-L268 PolarHBondContact O-N 3.05Å; V264-L268 VanDerWaalsContact O-N 3.13Å; V264-F344 HydrophobicContact CG1-CE1 3.93Å; V264-F344 HydrophobicContact CG1-CZ 3.73Å; V264-M362 HydrophobicContact CB-CE 4.33Å; V264-M362 HydrophobicContact CG1-CE 3.77Å; V264-M362 HydrophobicContact CG1-SD 4.16Å
265	M	92.3	Very high	91.3	Very high	0 Å²	0	17.5 Å²	17.5	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-59.3	-47.3	174.5	-69.4	177.3	177	0	0	111.6	W261 V262 V263 L268 G269 E270 L273 Q277 F344	W261-M265 HydrophobicContact CE3-CE 4.18Å; W261-M265 WeakPolarHBondContact O-CG 3.44Å; W261-M265 PolarHBondContact O-N 3.31Å; V262-M265 PolarHBondContact O-N 3.02Å; V263-M265 PolarHBondContact O-N 3.34Å; M265-L268 PolarHBondContact O-N 3.02Å; M265-G269 PolarHBondContact O-N 3.33Å; M265-E270 PolarHBondContact O-N 3.24Å; M265-L273 HydrophobicContact SD-CB 4.28Å; M265-Q277 HydrophobicContact SD-CB 4.15Å; M265-F344 HydrophobicContact CB-CD2 4.3Å; M265-F344 HydrophobicContact CB-CE2 4.03Å; M265-F344 HydrophobicContact CB-CZ 4.3Å; M265-F344 HydrophobicContact CE-CB 3.58Å; M265-F344 HydrophobicContact CE-CD1 3.81Å; M265-F344 HydrophobicContact CE-CD2 4.46Å; M265-F344 HydrophobicContact CE-CG 3.71Å; M265-F344 HydrophobicContact CG-CB 4.44Å; M265-F344 HydrophobicContact CG-CD1 3.94Å; M265-F344 HydrophobicContact CG-CD2 3.64Å; M265-F344 HydrophobicContact CG-CE1 3.94Å; M265-F344 HydrophobicContact CG-CE2 3.67Å; M265-F344 HydrophobicContact CG-CG 3.75Å; M265-F344 HydrophobicContact CG-CZ 3.77Å; M265-F344 HydrophobicContact SD-CG 4.43Å
266	M	91.6	Very high	91	Very high	0 Å²	0	17.8 Å²	17.8	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-67.4	-40.7	-179.1	-66.7	178.3	-175.5	0	0	112.7	M203 Y206 L207 V262 V263 L268 G269 Y271	M203-M266 HydrophobicContact CB-CE 4.35Å; M203-M266 HydrophobicContact CE-CE 3.91Å; M203-M266 HydrophobicContact CE-SD 3.35Å; M203-M266 WeakPolarHBondContact CE-SD 3.35Å; Y206-M266 HydrophobicContact CD1-CB 3.83Å; Y206-M266 HydrophobicContact CD1-CG 4.29Å; Y206-M266 HydrophobicContact CD1-SD 3.67Å; Y206-M266 HydrophobicContact CE1-CB 3.57Å; Y206-M266 HydrophobicContact CE1-CG 4.47Å; Y206-M266 HydrophobicContact CE1-SD 4.39Å; Y206-M266 HydrophobicContact CG-SD 4.47Å; L207-M266 HydrophobicContact CD1-CE 3.57Å; L207-M266 HydrophobicContact CD2-CE 3.61Å; L207-M266 HydrophobicContact CD2-CG 4.36Å; L207-M266 HydrophobicContact CD2-SD 4.05Å; L207-M266 HydrophobicContact CG-CE 3.4Å; L207-M266 VanDerWaalsContact CG-CE 3.4Å; L207-M266 HydrophobicContact CG-SD 3.95Å; V262-M266 HydrophobicContact CG1-CE 3.28Å; V262-M266 HydrophobicContact CG1-SD 4.16Å; V262-M266 VanDerWaalsContact O-CG 3.31Å; V262-M266 WeakPolarHBondContact O-CG 3.31Å; V262-M266 PolarHBondContact O-N 3.46Å; V263-M266 PolarHBondContact O-N 2.87Å; M266-L268 VanDerWaalsContact C-N 3.28Å; M266-L268 PolarHBondContact O-N 2.95Å; M266-G269 PolarHBondContact O-N 2.89Å; M266-Y271 HydrophobicContact CB-CD1 4.33Å; M266-Y271 HydrophobicContact CB-CE1 4.48Å; M266-Y271 HydrophobicContact CG-CD1 4.37Å
267	L	91.2	Very high	91	Very high	14 Å²	14	17.6 Å²	17.6	7%	0.073	10%	0.098	C	C	.	.	H	α-helix	trans	-61.1	-37.8	175.5	-72.4	172.8	0	0	0	111.8	F216 Y223 S226 M227 V263 V264 G269	F216-L267 HydrophobicContact CE2-CD2 3.79Å; F216-L267 HydrophobicContact CZ-CD2 4.07Å; Y223-L267 HydrophobicContact CD2-CD2 4.36Å; Y223-L267 HydrophobicContact CE2-CB 4.03Å; Y223-L267 HydrophobicContact CE2-CD2 4.24Å; Y223-L267 VanDerWaalsContact CE2-O 3.24Å; Y223-L267 WeakPolarHBondContact CE2-O 3.37Å; Y223-L267 PolarHBondContact OH-O 2.88Å; Y223-L267 VanDerWaalsContact OH-O 3.08Å; S226-L267 WeakPolarHBondContact OG-CD1 3.49Å; S226-L267 VanDerWaalsContact OG-CD2 3.32Å; S226-L267 WeakPolarHBondContact OG-CD2 3.3Å; M227-L267 HydrophobicContact CB-CD1 4.35Å; M227-L267 HydrophobicContact SD-CD1 4.26Å; V263-L267 HydrophobicContact CG1-CD1 3.88Å; V263-L267 HydrophobicContact CG1-CG 4.26Å; V263-L267 VanDerWaalsContact O-CG 3.31Å; V263-L267 WeakPolarHBondContact O-CG 3.36Å; V263-L267 PolarHBondContact O-N 2.92Å; V264-L267 PolarHBondContact O-N 3.48Å; L267-G269 PolarHBondContact O-N 3.48Å
268	L	89.1	Confident	90.9	Very high	41 Å²	41	17.6 Å²	17.6	22%	0.215	10%	0.097	C	C	.	.	T	Hydrogen-bonded Turn	trans	-76.6	-0.5	176.5	-68.8	177.7	0	0	0	114.1	V264 M265 M266 F344 I348 L358	V264-L268 HydrophobicContact CG1-CD1 4.29Å; V264-L268 WeakPolarHBondContact O-CG 3.31Å; V264-L268 PolarHBondContact O-N 3.05Å; V264-L268 VanDerWaalsContact O-N 3.13Å; M265-L268 PolarHBondContact O-N 3.02Å; M266-L268 VanDerWaalsContact C-N 3.28Å; M266-L268 PolarHBondContact O-N 2.95Å; L268-F344 HydrophobicContact CB-CE2 4.25Å; L268-F344 HydrophobicContact CB-CZ 4.5Å; L268-F344 HydrophobicContact CD1-CE1 4.44Å; L268-F344 HydrophobicContact CD1-CE2 3.81Å; L268-F344 HydrophobicContact CD1-CZ 3.42Å; L268-F344 VanDerWaalsContact CD1-CZ 3.42Å; L268-F344 HydrophobicContact CG-CZ 4.39Å; L268-I348 HydrophobicContact CD1-CD1 3.65Å; L268-I348 HydrophobicContact CD1-CG1 3.77Å; L268-L358 HydrophobicContact CD1-CD1 4.47Å; L268-L358 HydrophobicContact CD1-CD2 4.13Å
269	G	86.4	Confident	90.6	Very high	41 Å²	41	18.2 Å²	18.2	42%	0.423	10%	0.101	S	C	.	.	T	Hydrogen-bonded Turn	trans	90.3	5.2	177.7	0	0	0	0	0	114.9	M265 M266 L267 Y271	M265-G269 PolarHBondContact O-N 3.33Å; M266-G269 PolarHBondContact O-N 2.89Å; L267-G269 PolarHBondContact O-N 3.48Å; G269-Y271 VanDerWaalsContact C-N 3.33Å; G269-Y271 WeakPolarHBondContact O-CD2 3.17Å; G269-Y271 PolarHBondContact O-N 2.65Å
270	E	87	Confident	90.3	Very high	57 Å²	57	18.2 Å²	18.2	27%	0.266	10%	0.101	S	C	.	.			trans	-90.6	64.3	-179.5	-61.5	-76.5	-171.3	0	0	110.5	M265 D272 L273 G274 F344 S347	M265-E270 PolarHBondContact O-N 3.24Å; E270-D272 PolarHBondContact O-N 3.42Å; E270-L273 HydrophobicContact CB-CB 4.25Å; E270-L273 HydrophobicContact CB-CD1 4.16Å; E270-L273 HydrophobicContact CB-CG 4.48Å; E270-L273 HydrophobicContact CG-CD1 4.36Å; E270-L273 PolarHBondContact O-N 2.92Å; E270-G274 PolarHBondContact O-N 3.46Å; E270-F344 HydrophobicContact CB-CD2 4.28Å; E270-F344 HydrophobicContact CB-CE2 4.34Å; E270-F344 HydrophobicContact CG-CD2 4.08Å; E270-F344 HydrophobicContact CG-CE2 4.12Å; E270-S347 WeakPolarHBondContact OE1-CB 3.42Å; E270-S347 PolarHBondContact OE1-OG 3.33Å
271	Y	88.9	Confident	90.1	Very high	65 Å²	65	18.4 Å²	18.4	26%	0.255	10%	0.102	S	C	.	.	H	α-helix	trans	-62.5	-41	-174.6	-61.3	-74.3	0	0	0	112.8	Y206 L207 M266 G269 G274 L275	Y206-Y271 AromaticContact CE1-CE1 3.93Å; Y206-Y271 HydrophobicContact CE1-CE1 3.93Å; L207-Y271 HydrophobicContact CD2-CD1 3.95Å; L207-Y271 HydrophobicContact CD2-CG 4.48Å; M266-Y271 HydrophobicContact CB-CD1 4.33Å; M266-Y271 HydrophobicContact CB-CE1 4.48Å; M266-Y271 HydrophobicContact CG-CD1 4.37Å; G269-Y271 VanDerWaalsContact C-N 3.33Å; G269-Y271 WeakPolarHBondContact O-CD2 3.17Å; G269-Y271 PolarHBondContact O-N 2.65Å; Y271-G274 PolarHBondContact O-N 3.04Å; Y271-L275 WeakPolarHBondContact O-CB 3.49Å; Y271-L275 PolarHBondContact O-N 3.36Å
272	D	86.7	Confident	89.9	Confident	96 Å²	96	18.3 Å²	18.3	51%	0.513	10%	0.102	S	C	.	.	H	α-helix	trans	-67.4	-42.6	-178.1	-60.2	-34.4	0	0	0	111.8	E270 G274 L275 V276 L416	E270-D272 PolarHBondContact O-N 3.42Å; D272-G274 VanDerWaalsContact C-N 3.32Å; D272-G274 PolarHBondContact O-N 3.11Å; D272-L275 PolarHBondContact O-N 2.82Å; D272-V276 WeakPolarHBondContact O-CG2 3.45Å; D272-V276 PolarHBondContact O-N 3.25Å; D272-L416 HydrophobicContact CB-CD1 3.72Å; D272-L416 HydrophobicContact CB-CD2 3.82Å; D272-L416 HydrophobicContact CB-CG 4.38Å
273	L	87.3	Confident	89.5	Confident	6 Å²	6	18.9 Å²	18.9	3%	0.031	11%	0.105	C	C	.	.	H	α-helix	trans	-63.5	-40.5	174.1	-66.7	-179.4	0	0	0	111.3	M265 E270 L275 V276 Q277 A343 F344 L413	M265-L273 HydrophobicContact SD-CB 4.28Å; E270-L273 HydrophobicContact CB-CB 4.25Å; E270-L273 HydrophobicContact CB-CD1 4.16Å; E270-L273 HydrophobicContact CB-CG 4.48Å; E270-L273 HydrophobicContact CG-CD1 4.36Å; E270-L273 PolarHBondContact O-N 2.92Å; L273-L275 VanDerWaalsContact C-N 3.35Å; L273-V276 PolarHBondContact O-N 3.01Å; L273-Q277 VanDerWaalsContact O-CB 3.23Å; L273-Q277 WeakPolarHBondContact O-CB 3.43Å; L273-Q277 PolarHBondContact O-N 3.12Å; L273-A343 HydrophobicContact CD1-CB 4.27Å; L273-A343 HydrophobicContact CD2-CB 3.93Å; L273-F344 HydrophobicContact CD1-CB 4.14Å; L273-F344 HydrophobicContact CD1-CD2 4.45Å; L273-L413 HydrophobicContact CD2-CD2 3.56Å
274	G	91.1	Very high	89.1	Confident	0 Å²	0	18.4 Å²	18.4	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-60	-43.7	174.8	0	0	0	0	0	112.4	V262 E270 Y271 D272 Q277 L278	V262-G274 WeakPolarHBondContact CG1-O 3.45Å; E270-G274 PolarHBondContact O-N 3.46Å; Y271-G274 PolarHBondContact O-N 3.04Å; D272-G274 VanDerWaalsContact C-N 3.32Å; D272-G274 PolarHBondContact O-N 3.11Å; G274-Q277 PolarHBondContact O-N 3.01Å; G274-L278 WeakPolarHBondContact O-CB 3.49Å; G274-L278 PolarHBondContact O-N 2.97Å
275	L	89	Confident	89	Confident	18 Å²	18	18.4 Å²	18.4	9%	0.094	10%	0.102	C	C	.	.	H	α-helix	trans	-64.9	-49.5	177.4	178.7	136.9	0	0	0	112.2	I46 S49 L207 Y271 D272 L273 Q277 L278 V279	I46-L275 HydrophobicContact CB-CD1 3.95Å; I46-L275 HydrophobicContact CG1-CD1 3.89Å; I46-L275 HydrophobicContact CG2-CD1 3.82Å; S49-L275 WeakPolarHBondContact OG-CD1 3.38Å; S49-L275 WeakPolarHBondContact OG-CD2 3.46Å; L207-L275 HydrophobicContact CD1-CB 4.34Å; L207-L275 HydrophobicContact CD1-CD1 4.18Å; Y271-L275 WeakPolarHBondContact O-CB 3.49Å; Y271-L275 PolarHBondContact O-N 3.36Å; D272-L275 PolarHBondContact O-N 2.82Å; L273-L275 VanDerWaalsContact C-N 3.35Å; L275-Q277 VanDerWaalsContact C-N 3.27Å; L275-Q277 PolarHBondContact O-N 3.17Å; L275-L278 PolarHBondContact O-N 3.35Å; L275-L278 VanDerWaalsContact O-N 3.13Å; L275-V279 WeakPolarHBondContact O-CG2 3.33Å; L275-V279 PolarHBondContact O-N 3.45Å
276	V	86.8	Confident	88.8	Confident	6 Å²	6	18.4 Å²	18.4	4%	0.036	10%	0.102	C	C	.	.	H	α-helix	trans	-58.6	-44.5	178.1	170.9	0	0	0	0	110	D272 L273 L278 V279 I280 Y412 L416	D272-V276 WeakPolarHBondContact O-CG2 3.45Å; D272-V276 PolarHBondContact O-N 3.25Å; L273-V276 PolarHBondContact O-N 3.01Å; V276-L278 VanDerWaalsContact C-N 3.34Å; V276-L278 PolarHBondContact O-N 3.25Å; V276-V279 PolarHBondContact O-N 3.24Å; V276-I280 HydrophobicContact CG1-CD1 3.76Å; V276-I280 WeakPolarHBondContact O-CG1 3.34Å; V276-I280 PolarHBondContact O-N 2.83Å; V276-I280 VanDerWaalsContact O-N 3.11Å; V276-Y412 HydrophobicContact CG2-CD1 4.48Å; V276-Y412 HydrophobicContact CG2-CG 4.06Å; V276-L416 HydrophobicContact CG2-CD1 4.22Å
277	Q	90.5	Very high	88.6	Confident	0 Å²	0	18.6 Å²	18.6	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-61.4	-42.8	177.3	-178	157.8	-54.2	0	0	112.3	N258 V262 M265 L273 G274 L275 I280 H281 M337 S340	N258-Q277 PolarHBondContact O-NE2 3.14Å; V262-Q277 HydrophobicContact CG2-CB 4.08Å; V262-Q277 HydrophobicContact CG2-CG 3.77Å; M265-Q277 HydrophobicContact SD-CB 4.15Å; L273-Q277 VanDerWaalsContact O-CB 3.23Å; L273-Q277 WeakPolarHBondContact O-CB 3.43Å; L273-Q277 PolarHBondContact O-N 3.12Å; G274-Q277 PolarHBondContact O-N 3.01Å; L275-Q277 VanDerWaalsContact C-N 3.27Å; L275-Q277 PolarHBondContact O-N 3.17Å; Q277-I280 PolarHBondContact O-N 3.46Å; Q277-H281 WeakPolarHBondContact O-CB 3.28Å; Q277-H281 PolarHBondContact O-N 3.18Å; Q277-M337 VanDerWaalsContact CD-CE 3.49Å; Q277-M337 HydrophobicContact CG-CE 3.24Å; Q277-M337 HydrophobicContact CG-SD 3.97Å; Q277-S340 PolarHBondContact OE1-OG 3.3Å
278	L	91	Very high	88.5	Confident	5 Å²	5	18 Å²	18	3%	0.026	10%	0.1	C	C	.	.	H	α-helix	trans	-63.4	-42.5	-179.6	-175.1	151.1	0	0	0	111.7	M50 M53 A200 M203 V262 G274 L275 V276 H281 G282	M50-L278 HydrophobicContact CE-CD2 3.68Å; M50-L278 HydrophobicContact SD-CD2 3.29Å; M50-L278 WeakPolarHBondContact SD-CD2 3.22Å; M53-L278 HydrophobicContact CE-CD2 3.88Å; M53-L278 HydrophobicContact SD-CD2 3.88Å; A200-L278 HydrophobicContact CB-CD1 4.39Å; A200-L278 HydrophobicContact CB-CD2 4.2Å; M203-L278 HydrophobicContact CB-CD1 3.34Å; M203-L278 HydrophobicContact CG-CD1 3.9Å; V262-L278 HydrophobicContact CG1-CB 4.3Å; V262-L278 HydrophobicContact CG1-CD1 4.31Å; V262-L278 HydrophobicContact CG2-CB 4.31Å; G274-L278 WeakPolarHBondContact O-CB 3.49Å; G274-L278 PolarHBondContact O-N 2.97Å; L275-L278 PolarHBondContact O-N 3.35Å; L275-L278 VanDerWaalsContact O-N 3.13Å; V276-L278 VanDerWaalsContact C-N 3.34Å; V276-L278 PolarHBondContact O-N 3.25Å; L278-H281 PolarHBondContact O-N 3.49Å; L278-G282 PolarHBondContact O-N 2.97Å
279	V	87.7	Confident	88.6	Confident	13 Å²	13	16 Å²	16	8%	0.079	9%	0.09	C	C	.	.	H	α-helix	trans	-63.1	-49.3	177.6	171.6	0	0	0	0	111.4	M53 L275 V276 H281 G282 L283	M53-V279 HydrophobicContact CB-CG1 4.22Å; M53-V279 HydrophobicContact CB-CG2 4.41Å; L275-V279 WeakPolarHBondContact O-CG2 3.33Å; L275-V279 PolarHBondContact O-N 3.45Å; V276-V279 PolarHBondContact O-N 3.24Å; V279-H281 VanDerWaalsContact C-N 3.35Å; V279-H281 PolarHBondContact O-N 3Å; V279-G282 PolarHBondContact O-N 2.88Å; V279-L283 HydrophobicContact CG1-CD1 4.34Å; V279-L283 WeakPolarHBondContact O-CG 3.47Å; V279-L283 PolarHBondContact O-N 3.46Å; V279-L283 VanDerWaalsContact O-N 3.16Å
280	I	88	Confident	88.7	Confident	5 Å²	5	14.5 Å²	14.5	3%	0.026	7%	0.071	C	C	.	.	H	α-helix	trans	-64.3	-41.9	179.6	-63.4	169.5	0	0	0	110.7	V276 Q277 S284 C336 M337	V276-I280 HydrophobicContact CG1-CD1 3.76Å; V276-I280 WeakPolarHBondContact O-CG1 3.34Å; V276-I280 PolarHBondContact O-N 2.83Å; V276-I280 VanDerWaalsContact O-N 3.11Å; Q277-I280 PolarHBondContact O-N 3.46Å; I280-S284 WeakPolarHBondContact O-CB 3.5Å; I280-S284 PolarHBondContact O-N 3.04Å; I280-S284 PolarHBondContact O-OG 3.39Å; I280-C336 HydrophobicContact CG2-CB 3.84Å; I280-M337 HydrophobicContact CB-SD 3.87Å; I280-M337 HydrophobicContact CG2-CG 3.98Å; I280-M337 HydrophobicContact CG2-SD 3.64Å
281	H	90.3	Very high	88.6	Confident	4 Å²	4	11.8 Å²	11.8	2%	0.019	6%	0.059	C	C	.	.	H	α-helix	trans	-59.9	-48.4	175.3	168.6	-93.9	0	0	0	111.8	N258 I259 Q277 L278 V279 L283 S284 K285 M337	N258-H281 WeakPolarHBondContact CB-CD2 3.47Å; I259-H281 VanDerWaalsContact CD1-CE1 3.46Å; I259-H281 WeakPolarHBondContact CD1-CE1 3.46Å; Q277-H281 WeakPolarHBondContact O-CB 3.28Å; Q277-H281 PolarHBondContact O-N 3.18Å; L278-H281 PolarHBondContact O-N 3.49Å; V279-H281 VanDerWaalsContact C-N 3.35Å; V279-H281 PolarHBondContact O-N 3Å; H281-L283 PolarHBondContact O-N 2.99Å; H281-S284 WeakPolarHBondContact CA-OG 3.49Å; H281-S284 PolarHBondContact O-N 3.36Å; H281-S284 PolarHBondContact O-OG 3.26Å; H281-K285 VanDerWaalsContact NE2-CG 3.33Å; H281-K285 WeakPolarHBondContact NE2-CG 3.36Å; H281-K285 VanDerWaalsContact O-CB 3.23Å; H281-K285 WeakPolarHBondContact O-CB 3.28Å; H281-K285 VanDerWaalsContact O-CG 3.28Å; H281-K285 WeakPolarHBondContact O-CG 3.2Å; H281-K285 PolarHBondContact O-N 3.07Å; H281-M337 HydrophobicContact CB-CE 3.99Å; H281-M337 HydrophobicContact CB-SD 4.02Å
282	G	89.9	Confident	88.5	Confident	0 Å²	0	8.8 Å²	8.8	0%	0	5%	0.047	C	C	.	.	H	α-helix	trans	-60.5	-45.9	-177.9	0	0	0	0	0	112.5	S195 L278 V279 C286	S195-G282 WeakPolarHBondContact O-CA 3.4Å; L278-G282 PolarHBondContact O-N 2.97Å; V279-G282 PolarHBondContact O-N 2.88Å; G282-C286 WeakPolarHBondContact O-CB 3.38Å; G282-C286 PolarHBondContact O-N 2.86Å
283	L	86.6	Confident	88.6	Confident	13 Å²	13	4.2 Å²	4.2	7%	0.068	2%	0.023	C	C	.	.	H	α-helix	trans	-63.8	-51.4	177.2	-67.9	174.6	0	0	0	112	M53 C56 V279 H281 K285 C286 L287	M53-L283 HydrophobicContact CG-CG 4.35Å; C56-L283 HydrophobicContact CB-CD2 3.72Å; V279-L283 HydrophobicContact CG1-CD1 4.34Å; V279-L283 WeakPolarHBondContact O-CG 3.47Å; V279-L283 PolarHBondContact O-N 3.46Å; V279-L283 VanDerWaalsContact O-N 3.16Å; H281-L283 PolarHBondContact O-N 2.99Å; L283-K285 VanDerWaalsContact C-N 3.35Å; L283-K285 PolarHBondContact O-N 2.6Å; L283-C286 PolarHBondContact O-N 3.21Å; L283-L287 WeakPolarHBondContact O-CG 3.46Å; L283-L287 PolarHBondContact O-N 3.42Å
284	S	87.1	Confident	88.4	Confident	2 Å²	2	4 Å²	4	1%	0.014	2%	0.022	C	C	.	.	H	α-helix	trans	-62	-41.9	-179.1	54.8	0	0	0	0	111.9	I280 H281 L287 V288 L329	I280-S284 WeakPolarHBondContact O-CB 3.5Å; I280-S284 PolarHBondContact O-N 3.04Å; I280-S284 PolarHBondContact O-OG 3.39Å; H281-S284 WeakPolarHBondContact CA-OG 3.49Å; H281-S284 PolarHBondContact O-N 3.36Å; H281-S284 PolarHBondContact O-OG 3.26Å; S284-L287 PolarHBondContact O-N 3.29Å; S284-V288 VanDerWaalsContact O-CG2 3.22Å; S284-V288 WeakPolarHBondContact O-CG2 3.48Å; S284-V288 PolarHBondContact O-N 3.1Å; S284-L329 VanDerWaalsContact OG-CD2 3.23Å; S284-L329 WeakPolarHBondContact OG-CD2 3.26Å
285	K	90.6	Very high	87.9	Confident	0 Å²	0	4 Å²	4	0%	0	2%	0.022	C	C	.	.	H	α-helix	trans	-66	-39.4	176.9	-76.8	-68.3	-169.9	169.5	0	113.9	M251 S254 T255 H281 L283 L287 V288 F289 L329	M251-K285 HydrophobicContact CE-CD 4.29Å; M251-K285 PolarHBondContact O-NZ 3.23Å; S254-K285 VanDerWaalsContact CB-NZ 3.3Å; S254-K285 PolarHBondContact O-NZ 2.98Å; S254-K285 PolarHBondContact OG-NZ 3.33Å; T255-K285 HydrophobicContact CG2-CD 3.54Å; T255-K285 VanDerWaalsContact CG2-CE 3.42Å; T255-K285 HydrophobicContact CG2-CG 3.87Å; H281-K285 VanDerWaalsContact NE2-CG 3.33Å; H281-K285 WeakPolarHBondContact NE2-CG 3.36Å; H281-K285 VanDerWaalsContact O-CB 3.23Å; H281-K285 WeakPolarHBondContact O-CB 3.28Å; H281-K285 VanDerWaalsContact O-CG 3.28Å; H281-K285 WeakPolarHBondContact O-CG 3.2Å; H281-K285 PolarHBondContact O-N 3.07Å; L283-K285 VanDerWaalsContact C-N 3.35Å; L283-K285 PolarHBondContact O-N 2.6Å; K285-L287 VanDerWaalsContact C-N 3.25Å; K285-L287 PolarHBondContact O-N 3.45Å; K285-V288 PolarHBondContact O-N 3.28Å; K285-F289 VanDerWaalsContact O-CD2 3.25Å; K285-F289 WeakPolarHBondContact O-CD2 3.44Å; K285-F289 PolarHBondContact O-N 3.19Å; K285-L329 HydrophobicContact CD-CD1 4Å; K285-L329 HydrophobicContact CD-CD2 3.92Å; K285-L329 HydrophobicContact CG-CD2 3.95Å
286	C	88.7	Confident	87.8	Confident	0 Å²	0	3.4 Å²	3.4	0%	0	2%	0.018	C	C	.	.	H	α-helix	trans	-55.2	-46.9	174.2	-173.3	0	0	0	0	110.3	C57 S191 G282 L283 F289 I290	C57-C286 HydrophobicContact CB-CB 4.38Å; S191-C286 PolarHBondContact O-SG 3.09Å; S191-C286 VanDerWaalsContact O-SG 3.35Å; G282-C286 WeakPolarHBondContact O-CB 3.38Å; G282-C286 PolarHBondContact O-N 2.86Å; L283-C286 PolarHBondContact O-N 3.21Å; C286-F289 PolarHBondContact O-N 2.9Å; C286-I290 WeakPolarHBondContact O-CG1 3.17Å; C286-I290 PolarHBondContact O-N 3.33Å; C286-I290 VanDerWaalsContact O-N 3.09Å
287	L	87.7	Confident	87.5	Confident	4 Å²	4	5.3 Å²	5.3	2%	0.021	3%	0.032	C	C	.	.	H	α-helix	trans	-65.1	-40.4	178.1	-65	178.4	0	0	0	113.5	L60 L283 S284 K285 I290 L291 L325 L401 P402	L60-L287 HydrophobicContact CD1-CD2 4.08Å; L283-L287 WeakPolarHBondContact O-CG 3.46Å; L283-L287 PolarHBondContact O-N 3.42Å; S284-L287 PolarHBondContact O-N 3.29Å; K285-L287 VanDerWaalsContact C-N 3.25Å; K285-L287 PolarHBondContact O-N 3.45Å; L287-I290 PolarHBondContact O-N 3.47Å; L287-L291 PolarHBondContact O-N 3.32Å; L287-L325 HydrophobicContact CB-CD1 4.25Å; L287-L325 HydrophobicContact CB-CD2 3.71Å; L287-L325 HydrophobicContact CD1-CD2 3.93Å; L287-L325 HydrophobicContact CG-CD2 4.5Å; L287-L401 HydrophobicContact CD1-CB 3.84Å; L287-L401 HydrophobicContact CD1-CD1 4.42Å; L287-L401 HydrophobicContact CD2-CD1 4.18Å; L287-P402 HydrophobicContact CD1-CG 3.85Å
288	V	88.6	Confident	86.9	Confident	1 Å²	1	6 Å²	6	1%	0.006	4%	0.04	C	C	.	.	H	α-helix	trans	-68.5	-36.6	178.1	-167.1	0	0	0	0	111.7	M251 S284 K285 L291 V292 L325 L326 L329	M251-V288 HydrophobicContact CE-CB 3.6Å; M251-V288 HydrophobicContact CE-CG1 3.16Å; M251-V288 HydrophobicContact CE-CG2 4.32Å; M251-V288 HydrophobicContact SD-CG1 3.78Å; S284-V288 VanDerWaalsContact O-CG2 3.22Å; S284-V288 WeakPolarHBondContact O-CG2 3.48Å; S284-V288 PolarHBondContact O-N 3.1Å; K285-V288 PolarHBondContact O-N 3.28Å; V288-L291 PolarHBondContact O-N 2.74Å; V288-V292 HydrophobicContact CG1-CG2 4.31Å; V288-V292 WeakPolarHBondContact O-CB 3.4Å; V288-V292 VanDerWaalsContact O-CG2 3.27Å; V288-V292 WeakPolarHBondContact O-CG2 3.33Å; V288-V292 PolarHBondContact O-N 3.23Å; V288-L325 HydrophobicContact CG2-CB 4.01Å; V288-L325 HydrophobicContact CG2-CD1 4.39Å; V288-L325 HydrophobicContact CG2-CD2 4.42Å; V288-L326 HydrophobicContact CG1-CD2 3.88Å; V288-L329 HydrophobicContact CG2-CD1 3.76Å
289	F	91.1	Very high	86.2	Confident	1 Å²	1	6.3 Å²	6.3	0%	0.004	4%	0.043	C	C	.	.	H	α-helix	trans	-66.7	-36.9	175.1	-83.3	-65.5	0	0	0	112.8	M183 M251 T255 K285 C286 V292 G293	M183-F289 HydrophobicContact CE-CE1 4.09Å; M183-F289 HydrophobicContact CE-CZ 3.69Å; M183-F289 HydrophobicContact SD-CE1 3.83Å; M183-F289 HydrophobicContact SD-CZ 4.08Å; M251-F289 HydrophobicContact CB-CD1 4.42Å; M251-F289 HydrophobicContact CB-CE1 3.69Å; M251-F289 HydrophobicContact CB-CZ 3.82Å; T255-F289 HydrophobicContact CG2-CE2 4.19Å; K285-F289 VanDerWaalsContact O-CD2 3.25Å; K285-F289 WeakPolarHBondContact O-CD2 3.44Å; K285-F289 PolarHBondContact O-N 3.19Å; C286-F289 PolarHBondContact O-N 2.9Å; F289-V292 PolarHBondContact O-N 3.07Å; F289-G293 PolarHBondContact O-N 3.18Å
290	I	87.6	Confident	85.7	Confident	8 Å²	8	15.6 Å²	15.6	4%	0.041	8%	0.083	C	C	.	.	H	α-helix	trans	-59.8	-50.2	172	-71.7	167.9	0	0	0	109.9	L60 Y64 C286 L287 V292 G293 D294	L60-I290 HydrophobicContact CB-CD1 4.04Å; Y64-I290 HydrophobicContact CD1-CG1 3.94Å; Y64-I290 HydrophobicContact CD2-CB 4.33Å; Y64-I290 HydrophobicContact CD2-CG1 4.24Å; Y64-I290 HydrophobicContact CD2-CG2 3.62Å; Y64-I290 HydrophobicContact CE1-CG1 4.48Å; Y64-I290 HydrophobicContact CE2-CB 4.46Å; Y64-I290 HydrophobicContact CE2-CG2 3.83Å; Y64-I290 HydrophobicContact CG-CB 4.39Å; Y64-I290 HydrophobicContact CG-CG1 3.82Å; Y64-I290 HydrophobicContact CG-CG2 4.1Å; Y64-I290 PolarHBondContact OH-O 3.26Å; C286-I290 WeakPolarHBondContact O-CG1 3.17Å; C286-I290 PolarHBondContact O-N 3.33Å; C286-I290 VanDerWaalsContact O-N 3.09Å; L287-I290 PolarHBondContact O-N 3.47Å; I290-V292 PolarHBondContact O-N 3.14Å; I290-G293 PolarHBondContact O-N 3.09Å; I290-D294 PolarHBondContact O-N 2.7Å
291	L	85.9	Confident	85.3	Confident	1 Å²	1	17.3 Å²	17.3	1%	0.005	10%	0.102	C	C	.	.	H	α-helix	trans	-57.7	-50.1	176.7	177.8	138.3	0	0	0	111.5	L287 V288 G293 D294 Y295 Y321 L322 L325 F380 Y395	L287-L291 PolarHBondContact O-N 3.32Å; V288-L291 PolarHBondContact O-N 2.74Å; L291-G293 PolarHBondContact O-N 3.21Å; L291-D294 PolarHBondContact O-N 3.27Å; L291-D294 VanDerWaalsContact O-N 3.13Å; L291-Y295 HydrophobicContact CD1-CE2 4.16Å; L291-Y295 HydrophobicContact CD2-CD2 3.92Å; L291-Y295 HydrophobicContact CD2-CE2 3.89Å; L291-Y295 HydrophobicContact CG-CD2 3.94Å; L291-Y295 HydrophobicContact CG-CE2 3.77Å; L291-Y295 WeakPolarHBondContact O-CD2 3.42Å; L291-Y295 PolarHBondContact O-N 3.47Å; L291-Y321 HydrophobicContact CD1-CD1 3.75Å; L291-Y321 HydrophobicContact CD1-CE1 3.61Å; L291-L322 HydrophobicContact CD1-CD2 3.37Å; L291-L322 HydrophobicContact CD1-CG 3.95Å; L291-L322 HydrophobicContact CD2-CD2 3.45Å; L291-L322 VanDerWaalsContact CD2-CD2 3.45Å; L291-L322 HydrophobicContact CG-CD2 4.03Å; L291-L325 HydrophobicContact CD1-CD1 4.31Å; L291-F380 HydrophobicContact CD2-CD1 4.04Å; L291-F380 HydrophobicContact CD2-CE1 3.41Å; L291-F380 VanDerWaalsContact CD2-CE1 3.41Å; L291-F380 HydrophobicContact CD2-CE2 4.12Å; L291-F380 HydrophobicContact CD2-CZ 3.45Å; L291-F380 VanDerWaalsContact CD2-CZ 3.45Å; L291-Y395 HydrophobicContact CD1-CE1 3.62Å; L291-Y395 WeakPolarHBondContact CD1-OH 3.23Å; L291-Y395 HydrophobicContact CG-CE1 4.39Å; L291-Y395 VanDerWaalsContact CG-OH 3.29Å; L291-Y395 WeakPolarHBondContact CG-OH 3.47Å
292	V	87.3	Confident	84.9	Confident	2 Å²	2	17.6 Å²	17.6	1%	0.012	11%	0.106	C	C	.	.	H	α-helix	trans	-57.5	-41.5	178.8	167.2	0	0	0	0	111.1	M247 K248 M251 V288 F289 I290 Y295 I296 F380	M247-V292 HydrophobicContact CB-CG1 4.29Å; K248-V292 HydrophobicContact CG-CG1 4.12Å; M251-V292 HydrophobicContact CG-CG2 3.93Å; V288-V292 HydrophobicContact CG1-CG2 4.31Å; V288-V292 WeakPolarHBondContact O-CB 3.4Å; V288-V292 VanDerWaalsContact O-CG2 3.27Å; V288-V292 WeakPolarHBondContact O-CG2 3.33Å; V288-V292 PolarHBondContact O-N 3.23Å; F289-V292 PolarHBondContact O-N 3.07Å; I290-V292 PolarHBondContact O-N 3.14Å; V292-Y295 PolarHBondContact O-N 3.42Å; V292-I296 HydrophobicContact CG1-CD1 3.6Å; V292-I296 HydrophobicContact CG1-CG1 4.27Å; V292-I296 VanDerWaalsContact O-CG1 3.23Å; V292-I296 WeakPolarHBondContact O-CG1 3.5Å; V292-I296 PolarHBondContact O-N 3.41Å; V292-F380 HydrophobicContact CG2-CE1 4.02Å; V292-F380 HydrophobicContact CG2-CZ 3.54Å
293	G	87.4	Confident	84.7	Confident	0 Å²	0	20.5 Å²	20.5	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-67.8	-34.8	179.4	0	0	0	0	0	113.3	Y64 F289 I290 L291 I296 S297	Y64-G293 WeakPolarHBondContact OH-CA 3.35Å; F289-G293 PolarHBondContact O-N 3.18Å; I290-G293 PolarHBondContact O-N 3.09Å; L291-G293 PolarHBondContact O-N 3.21Å; G293-I296 PolarHBondContact O-N 3.3Å; G293-S297 WeakPolarHBondContact O-CB 3.15Å; G293-S297 PolarHBondContact O-N 2.99Å
294	D	82.8	Confident	84.6	Confident	0 Å²	0	25.7 Å²	25.7	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-64.4	-42.3	171.8	-74.5	-26.7	0	0	0	111.6	Y64 H67 I290 L291 S297 G298 Y395	Y64-D294 VanDerWaalsContact CE2-OD1 3.31Å; Y64-D294 WeakPolarHBondContact CE2-OD1 2.98Å; Y64-D294 PolarHBondContact OH-N 3.42Å; H67-D294 IonicContact CE1-OD1 3.32Å; H67-D294 PolarHBondContact CE1-OD1 2.94Å; H67-D294 IonicContact ND1-OD1 3.32Å; H67-D294 PolarHBondContact ND1-OD1 3.26Å; I290-D294 PolarHBondContact O-N 2.7Å; L291-D294 PolarHBondContact O-N 3.27Å; L291-D294 VanDerWaalsContact O-N 3.13Å; D294-S297 PolarHBondContact O-N 3.43Å; D294-S297 PolarHBondContact O-OG 3.26Å; D294-G298 PolarHBondContact O-N 2.94Å; D294-Y395 WeakPolarHBondContact OD2-CE2 3.37Å
295	Y	82.2	Confident	84.1	Confident	2 Å²	2	26.6 Å²	26.6	1%	0.008	15%	0.147	C	C	.	.	H	α-helix	trans	-64	-41	175	-83.7	-108.5	0	0	0	112.3	L291 V292 S297 G298 G299 V308 V310 L322 F380 I391 Y395	L291-Y295 HydrophobicContact CD1-CE2 4.16Å; L291-Y295 HydrophobicContact CD2-CD2 3.92Å; L291-Y295 HydrophobicContact CD2-CE2 3.89Å; L291-Y295 HydrophobicContact CG-CD2 3.94Å; L291-Y295 HydrophobicContact CG-CE2 3.77Å; L291-Y295 WeakPolarHBondContact O-CD2 3.42Å; L291-Y295 PolarHBondContact O-N 3.47Å; V292-Y295 PolarHBondContact O-N 3.42Å; Y295-S297 VanDerWaalsContact C-N 3.33Å; Y295-S297 PolarHBondContact O-N 2.76Å; Y295-G298 PolarHBondContact O-N 3.49Å; Y295-G299 PolarHBondContact O-N 3.41Å; Y295-V308 HydrophobicContact CD1-CG1 3.98Å; Y295-V310 HydrophobicContact CD1-CB 3.57Å; Y295-V310 HydrophobicContact CD1-CG1 3.94Å; Y295-V310 HydrophobicContact CD1-CG2 3.92Å; Y295-V310 HydrophobicContact CE1-CB 3.6Å; Y295-V310 HydrophobicContact CE1-CG1 3.54Å; Y295-V310 HydrophobicContact CE1-CG2 4.39Å; Y295-V310 HydrophobicContact CG-CG2 4.5Å; Y295-L322 WeakPolarHBondContact OH-CD1 3.31Å; Y295-F380 AromaticContact CD1-CD1 3.53Å; Y295-F380 HydrophobicContact CD1-CD1 3.53Å; Y295-F380 HydrophobicContact CD1-CE1 4.22Å; Y295-F380 HydrophobicContact CD2-CD1 4.21Å; Y295-F380 HydrophobicContact CD2-CE1 4.28Å; Y295-F380 HydrophobicContact CE1-CB 4.12Å; Y295-F380 AromaticContact CE1-CD1 3.73Å; Y295-F380 HydrophobicContact CE1-CD1 3.73Å; Y295-F380 HydrophobicContact CE1-CG 4.37Å; Y295-F380 HydrophobicContact CE2-CD1 4.36Å; Y295-F380 AromaticContact CG-CD1 3.79Å; Y295-F380 HydrophobicContact CG-CD1 3.79Å; Y295-F380 HydrophobicContact CG-CE1 4Å; Y295-I391 HydrophobicContact CE2-CD1 4.31Å; Y295-Y395 WeakPolarHBondContact CE2-OH 3.36Å
296	I	85.3	Confident	83.3	Confident	4 Å²	4	33.3 Å²	33.3	2%	0.021	18%	0.183	C	C	.	.	H	α-helix	trans	-62.5	-41.4	174.1	-68.9	164.8	0	0	0	110.5	T187 K248 V292 G293 G298 G299 F300 G301 Q303	T187-I296 HydrophobicContact CG2-CD1 4.08Å; K248-I296 HydrophobicContact CD-CD1 4.23Å; K248-I296 HydrophobicContact CG-CD1 3.96Å; V292-I296 HydrophobicContact CG1-CD1 3.6Å; V292-I296 HydrophobicContact CG1-CG1 4.27Å; V292-I296 VanDerWaalsContact O-CG1 3.23Å; V292-I296 WeakPolarHBondContact O-CG1 3.5Å; V292-I296 PolarHBondContact O-N 3.41Å; G293-I296 PolarHBondContact O-N 3.3Å; I296-G298 VanDerWaalsContact C-N 3.34Å; I296-G298 PolarHBondContact O-N 3.27Å; I296-G299 CarbonylContact O-C 3.59Å; I296-G299 PolarHBondContact O-N 3.17Å; I296-F300 PolarHBondContact O-N 2.91Å; I296-G301 WeakPolarHBondContact O-CA 3.32Å; I296-G301 PolarHBondContact O-N 3.35Å; I296-Q303 HydrophobicContact CD1-CG 4.24Å; I296-Q303 HydrophobicContact CG2-CG 4.32Å
297	S	80.8	Confident	82.6	Confident	47 Å²	47	37.3 Å²	37.3	33%	0.329	20%	0.202	S	C	.	.	H	α-helix	trans	-63.7	-39.8	177.1	79.4	0	0	0	0	111.9	G293 D294 Y295 G299 F300	G293-S297 WeakPolarHBondContact O-CB 3.15Å; G293-S297 PolarHBondContact O-N 2.99Å; D294-S297 PolarHBondContact O-N 3.43Å; D294-S297 PolarHBondContact O-OG 3.26Å; Y295-S297 VanDerWaalsContact C-N 3.33Å; Y295-S297 PolarHBondContact O-N 2.76Å; S297-G299 VanDerWaalsContact C-N 3.32Å; S297-G299 PolarHBondContact O-N 2.89Å; S297-F300 PolarHBondContact O-N 3.06Å
298	G	77.6	Confident	81.8	Confident	15 Å²	15	37.5 Å²	37.5	16%	0.155	20%	0.203	C	C	.	.	H	α-helix	trans	-67.2	-29.2	174.7	0	0	0	0	0	113.9	D294 Y295 I296 F300	D294-G298 PolarHBondContact O-N 2.94Å; Y295-G298 PolarHBondContact O-N 3.49Å; I296-G298 VanDerWaalsContact C-N 3.34Å; I296-G298 PolarHBondContact O-N 3.27Å; G298-F300 VanDerWaalsContact C-N 3.31Å; G298-F300 PolarHBondContact O-N 3.49Å
299	G	76.4	Confident	80.7	Confident	10 Å²	10	41.9 Å²	41.9	10%	0.103	22%	0.224	C	C	.	.	T	Hydrogen-bonded Turn	trans	-88.7	23.5	174.3	0	0	0	0	0	114.7	Y295 I296 S297 G301 G302	Y295-G299 PolarHBondContact O-N 3.41Å; I296-G299 CarbonylContact O-C 3.59Å; I296-G299 PolarHBondContact O-N 3.17Å; S297-G299 VanDerWaalsContact C-N 3.32Å; S297-G299 PolarHBondContact O-N 2.89Å; G299-G301 PolarHBondContact O-N 3.05Å; G299-G302 PolarHBondContact O-N 3.04Å; G299-G302 VanDerWaalsContact O-N 3.12Å
300	F	78.6	Confident	79.6	Confident	208 Å²	208	41.9 Å²	41.9	91%	0.912	23%	0.225	S	C	*	.	T	Hydrogen-bonded Turn	trans	54.9	34.4	-179.3	-58.3	-78.1	0	0	0	114.5	I296 S297 G298	I296-F300 PolarHBondContact O-N 2.91Å; S297-F300 PolarHBondContact O-N 3.06Å; G298-F300 VanDerWaalsContact C-N 3.31Å; G298-F300 PolarHBondContact O-N 3.49Å
301	G	79.5	Confident	78.8	Confident	42 Å²	42	43 Å²	43	43%	0.433	23%	0.233	S	C	.	.	T	Hydrogen-bonded Turn	trans	88	2.1	178.3	0	0	0	0	0	114.9	I296 G299 Q303	I296-G301 WeakPolarHBondContact O-CA 3.32Å; I296-G301 PolarHBondContact O-N 3.35Å; G299-G301 PolarHBondContact O-N 3.05Å; G301-Q303 PolarHBondContact O-N 3.32Å
302	G	82.1	Confident	78.1	Confident	9 Å²	9	43.2 Å²	43.2	9%	0.093	23%	0.234	C	C	.	.			trans	-65.3	120.3	174.2	0	0	0	0	0	112.3	G299	G299-G302 PolarHBondContact O-N 3.04Å; G299-G302 VanDerWaalsContact O-N 3.12Å
303	Q	85.5	Confident	77	Confident	62 Å²	62	48.9 Å²	48.9	29%	0.29	26%	0.264	S	S	.	.			trans	-97.8	-19.5	179.9	-62.7	-179.4	21.5	0	0	113.2	M247 I296 G301	M247-Q303 PolarHBondContact N-O 2.66Å; I296-Q303 HydrophobicContact CD1-CG 4.24Å; I296-Q303 HydrophobicContact CG2-CG 4.32Å; G301-Q303 PolarHBondContact O-N 3.32Å
304	K	84.1	Confident	75.9	Confident	122 Å²	122	53.2 Å²	53.2	53%	0.53	31%	0.308	S	S	.	.	B	Isolated β-bridge	trans	-72.2	144	180	-66.7	-178.6	179.3	179.5	0	109.3	N245 D246 N306 Q307	N245-K304 CarbonylContact O-C 3.54Å; N245-K304 VanDerWaalsContact O-CA 3.32Å; N245-K304 WeakPolarHBondContact O-CA 3.26Å; D246-K304 WeakPolarHBondContact OD1-CG 3.33Å; K304-N306 PolarHBondContact O-N 3.16Å; K304-N306 VanDerWaalsContact O-N 3.11Å; K304-Q307 HydrophobicContact CB-CG 4.19Å; K304-Q307 WeakPolarHBondContact O-CB 3.42Å; K304-Q307 PolarHBondContact O-N 3.16Å
305	V	77.2	Confident	75.5	Confident	20 Å²	20	55.1 Å²	55.1	12%	0.121	32%	0.321	C	S	.	.	G	3₁₀ helix	trans	-46.2	-45.2	176.6	176	0	0	0	0	112.1	N245 M247 Q307 V308 L379	N245-V305 VanDerWaalsContact O-CG2 3.29Å; N245-V305 WeakPolarHBondContact O-CG2 3.25Å; N245-V305 PolarHBondContact O-N 3.33Å; M247-V305 HydrophobicContact SD-CG2 3.91Å; V305-Q307 PolarHBondContact O-N 3.3Å; V305-Q307 VanDerWaalsContact O-N 3.12Å; V305-V308 PolarHBondContact O-N 3.09Å; V305-L379 HydrophobicContact CB-CD1 4.44Å; V305-L379 HydrophobicContact CG1-CB 4.13Å; V305-L379 HydrophobicContact CG1-CD1 3.88Å; V305-L379 HydrophobicContact CG1-CD2 3.28Å; V305-L379 HydrophobicContact CG1-CG 3.89Å; V305-L379 HydrophobicContact CG2-CD1 3.58Å; V305-L379 HydrophobicContact CG2-CG 4.47Å
306	N	73.5	Confident	75.3	Confident	142 Å²	142	62 Å²	62	76%	0.759	36%	0.357	S	S	*	.	G	3₁₀ helix	trans	-69.4	-9.8	-176.4	-58.3	4.7	0	0	0	114.3	K304	K304-N306 PolarHBondContact O-N 3.16Å; K304-N306 VanDerWaalsContact O-N 3.11Å
307	Q	73.1	Confident	75	Confident	84 Å²	84	67.1 Å²	67.1	39%	0.393	38%	0.376	S	S	.	.	G	3₁₀ helix	trans	-102.2	-4.6	-178.5	-62.5	176	-36.3	0	0	112.4	K304 V305 M309	K304-Q307 HydrophobicContact CB-CG 4.19Å; K304-Q307 WeakPolarHBondContact O-CB 3.42Å; K304-Q307 PolarHBondContact O-N 3.16Å; V305-Q307 PolarHBondContact O-N 3.3Å; V305-Q307 VanDerWaalsContact O-N 3.12Å; Q307-M309 PolarHBondContact O-N 3.21Å
308	V	71.9	Confident	74.8	Confident	7 Å²	7	65.9 Å²	65.9	4%	0.042	37%	0.365	C	S	.	.			trans	-75.9	109.5	175	-177.4	0	0	0	0	107.6	M247 Y295 V305 G382	M247-V308 HydrophobicContact CG-CG2 4.06Å; Y295-V308 HydrophobicContact CD1-CG1 3.98Å; V305-V308 PolarHBondContact O-N 3.09Å; V308-G382 WeakPolarHBondContact O-CA 3.13Å
309	M	65.5	Low	75	Confident	94 Å²	94	69 Å²	69	46%	0.463	38%	0.375	S	S	.	.			trans	-104.3	12.5	-175.1	-61.1	-61.5	178.6	0	0	113.3	Q307 S386	Q307-M309 PolarHBondContact O-N 3.21Å; M309-S386 PolarHBondContact O-OG 3.1Å
310	V	67.4	Low	75.4	Confident	1 Å²	1	72.2 Å²	72.2	1%	0.006	39%	0.392	C	S	.	.			trans	-96.7	129.7	-177.4	-171.3	0	0	0	0	108.3	Y295 G382 V388 I391	Y295-V310 HydrophobicContact CD1-CB 3.57Å; Y295-V310 HydrophobicContact CD1-CG1 3.94Å; Y295-V310 HydrophobicContact CD1-CG2 3.92Å; Y295-V310 HydrophobicContact CE1-CB 3.6Å; Y295-V310 HydrophobicContact CE1-CG1 3.54Å; Y295-V310 HydrophobicContact CE1-CG2 4.39Å; Y295-V310 HydrophobicContact CG-CG2 4.5Å; V310-G382 CarbonylContact C-O 3.3Å; V310-G382 VanDerWaalsContact C-O 3.3Å; V310-G382 PolarHBondContact O-N 3Å; V310-V388 HydrophobicContact CB-CG2 4.45Å; V310-V388 HydrophobicContact CG1-CG2 4.22Å; V310-V388 HydrophobicContact CG2-CB 4.48Å; V310-V388 HydrophobicContact CG2-CG2 3.53Å; V310-I391 HydrophobicContact CG1-CD1 3.86Å
311	S	70.3	Confident	75.6	Confident	32 Å²	32	62.4 Å²	62.4	22%	0.224	35%	0.349	C	S	.	.			trans	-106.8	136.1	167.8	-179.5	0	0	0	0	109.6	L313 D381 G382	S311-L313 WeakPolarHBondContact OG-CB 3.27Å; S311-L313 PolarHBondContact OG-N 2.72Å; S311-L313 VanDerWaalsContact OG-N 3.13Å; S311-D381 PolarHBondContact OG-OD1 2.98Å; S311-G382 PolarHBondContact N-O 3.49Å
312	F	71.1	Confident	75.9	Confident	4 Å²	4	60.5 Å²	60.5	2%	0.018	33%	0.329	C	S	.	.			trans	-91	-10.5	169	60.1	-103.2	0	0	0	112	G314 C315 E318 F319 L322 F377 F380 D381	F312-G314 PolarHBondContact O-N 3.24Å; F312-C315 PolarHBondContact O-N 3.42Å; F312-C315 VanDerWaalsContact O-N 3.13Å; F312-E318 HydrophobicContact CB-CB 4.41Å; F312-F319 HydrophobicContact CD2-CB 4.36Å; F312-F319 AromaticContact CD2-CD2 3.77Å; F312-F319 HydrophobicContact CD2-CD2 3.77Å; F312-F319 AromaticContact CE2-CD2 3.6Å; F312-F319 HydrophobicContact CE2-CD2 3.6Å; F312-F319 HydrophobicContact CE2-CE2 4.07Å; F312-L322 HydrophobicContact CB-CD1 3.81Å; F312-L322 HydrophobicContact CD1-CD1 3.45Å; F312-L322 VanDerWaalsContact CD1-CD1 3.45Å; F312-L322 HydrophobicContact CE1-CD1 4.15Å; F312-L322 HydrophobicContact CG-CD1 3.73Å; F312-F377 WeakPolarHBondContact CE1-O 3.29Å; F312-F377 HydrophobicContact CE2-CE1 4.25Å; F312-F377 AromaticContact CE2-CZ 3.95Å; F312-F377 HydrophobicContact CE2-CZ 3.95Å; F312-F377 HydrophobicContact CZ-CD1 4.37Å; F312-F377 AromaticContact CZ-CE1 3.82Å; F312-F377 HydrophobicContact CZ-CE1 3.82Å; F312-F377 HydrophobicContact CZ-CE2 4.38Å; F312-F377 AromaticContact CZ-CZ 3.81Å; F312-F377 HydrophobicContact CZ-CZ 3.81Å; F312-F380 HydrophobicContact CD1-CB 4.1Å; F312-F380 HydrophobicContact CE1-CB 4.07Å; F312-D381 HydrophobicContact CD1-CB 4.08Å; F312-D381 HydrophobicContact CE1-CB 3.39Å; F312-D381 HydrophobicContact CE2-CB 4.48Å; F312-D381 HydrophobicContact CZ-CB 3.62Å
313	L	64.7	Low	76.2	Confident	122 Å²	122	62.9 Å²	62.9	64%	0.639	34%	0.337	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.4	111.5	176.8	-72.7	171.7	0	0	0	109	S311 D381	S311-L313 WeakPolarHBondContact OG-CB 3.27Å; S311-L313 PolarHBondContact OG-N 2.72Å; S311-L313 VanDerWaalsContact OG-N 3.13Å; L313-D381 WeakPolarHBondContact CD1-OD2 3.41Å; L313-D381 WeakPolarHBondContact CG-OD1 3.34Å; L313-D381 VanDerWaalsContact CG-OD2 3.26Å; L313-D381 WeakPolarHBondContact CG-OD2 3.3Å
314	G	64.6	Low	76.2	Confident	90 Å²	90	61.3 Å²	61.3	93%	0.928	33%	0.332	S	S	*	.	T	Hydrogen-bonded Turn	trans	119.9	-10.4	-177.9	0	0	0	0	0	114.6	F312	F312-G314 PolarHBondContact O-N 3.24Å
315	C	74.4	Confident	76.3	Confident	41 Å²	41	55.7 Å²	55.7	28%	0.277	31%	0.307	S	S	.	.			trans	-121.3	100.7	170.1	-166.2	0	0	0	0	111.2	F312 R317 E318 F319	F312-C315 PolarHBondContact O-N 3.42Å; F312-C315 VanDerWaalsContact O-N 3.13Å; C315-R317 PolarHBondContact O-N 2.72Å; C315-R317 VanDerWaalsContact O-N 3.14Å; C315-E318 HydrophobicContact CB-CB 4.13Å; C315-E318 HydrophobicContact CB-CG 4.17Å; C315-E318 PolarHBondContact O-N 3.35Å; C315-E318 VanDerWaalsContact O-N 3.12Å; C315-F319 PolarHBondContact O-N 3.45Å
316	L	77.9	Confident	76.9	Confident	147 Å²	147	54.8 Å²	54.8	77%	0.77	30%	0.302	S	S	*	.	H	α-helix	trans	-53.4	-36.4	178.1	-72.9	175.1	0	0	0	112.7	F319 V320	L316-F319 PolarHBondContact O-N 3.02Å; L316-V320 VanDerWaalsContact O-CG2 3.28Å; L316-V320 WeakPolarHBondContact O-CG2 3.37Å; L316-V320 PolarHBondContact O-N 2.86Å
317	R	78	Confident	77.7	Confident	111 Å²	111	48.3 Å²	48.3	42%	0.419	27%	0.267	S	S	.	.	H	α-helix	trans	-63.7	-45.7	179.7	-174.9	-177	65.6	175.8	3.7	112.2	C315 Y321 L399	C315-R317 PolarHBondContact O-N 2.72Å; C315-R317 VanDerWaalsContact O-N 3.14Å; R317-Y321 WeakPolarHBondContact O-CB 3.4Å; R317-Y321 PolarHBondContact O-N 2.89Å; R317-L399 HydrophobicContact CG-CD1 4.38Å
318	E	77.5	Confident	78.5	Confident	21 Å²	21	44.3 Å²	44.3	10%	0.098	25%	0.248	C	C	.	.	H	α-helix	trans	-70.4	-39.3	-179.7	-70.4	168.8	-167.1	0	0	110.9	F312 C315 Y321 L322 I391	F312-E318 HydrophobicContact CB-CB 4.41Å; C315-E318 HydrophobicContact CB-CB 4.13Å; C315-E318 HydrophobicContact CB-CG 4.17Å; C315-E318 PolarHBondContact O-N 3.35Å; C315-E318 VanDerWaalsContact O-N 3.12Å; E318-Y321 PolarHBondContact O-N 2.97Å; E318-L322 WeakPolarHBondContact O-CB 3.39Å; E318-L322 WeakPolarHBondContact O-CG 3.46Å; E318-L322 PolarHBondContact O-N 3.45Å; E318-I391 HydrophobicContact CG-CG2 4.44Å
319	F	82.4	Confident	79.3	Confident	81 Å²	81	44.1 Å²	44.1	36%	0.355	25%	0.247	S	C	.	.	H	α-helix	trans	-55.9	-53.6	172.5	180	-84	0	0	0	111.7	F312 C315 L316 Y321 L322 F323 F377	F312-F319 HydrophobicContact CD2-CB 4.36Å; F312-F319 AromaticContact CD2-CD2 3.77Å; F312-F319 HydrophobicContact CD2-CD2 3.77Å; F312-F319 AromaticContact CE2-CD2 3.6Å; F312-F319 HydrophobicContact CE2-CD2 3.6Å; F312-F319 HydrophobicContact CE2-CE2 4.07Å; C315-F319 PolarHBondContact O-N 3.45Å; L316-F319 PolarHBondContact O-N 3.02Å; F319-Y321 VanDerWaalsContact C-N 3.31Å; F319-Y321 PolarHBondContact O-N 2.66Å; F319-L322 PolarHBondContact O-N 2.97Å; F319-F323 WeakPolarHBondContact O-CB 3.42Å; F319-F323 PolarHBondContact O-N 3.47Å; F319-F377 AromaticContact CD2-CZ 3.86Å; F319-F377 HydrophobicContact CD2-CZ 3.86Å; F319-F377 HydrophobicContact CE2-CE1 4.11Å; F319-F377 AromaticContact CE2-CZ 3.46Å; F319-F377 HydrophobicContact CE2-CZ 3.46Å; F319-F377 VanDerWaalsContact CE2-CZ 3.46Å; F319-F377 AromaticContact CZ-CZ 3.87Å; F319-F377 HydrophobicContact CZ-CZ 3.87Å
320	V	83.8	Confident	80.4	Confident	76 Å²	76	39.6 Å²	39.6	46%	0.461	23%	0.225	S	C	.	.	H	α-helix	trans	-63.2	-39.7	-179.4	172.5	0	0	0	0	110.9	L316 F323 T324	L316-V320 VanDerWaalsContact O-CG2 3.28Å; L316-V320 WeakPolarHBondContact O-CG2 3.37Å; L316-V320 PolarHBondContact O-N 2.86Å; V320-F323 PolarHBondContact O-N 3.32Å; V320-T324 HydrophobicContact CG1-CG2 4.26Å; V320-T324 WeakPolarHBondContact O-CB 3.25Å; V320-T324 VanDerWaalsContact O-CG2 3.23Å; V320-T324 WeakPolarHBondContact O-CG2 3.38Å; V320-T324 PolarHBondContact O-N 3.46Å; V320-T324 PolarHBondContact O-OG1 2.84Å
321	Y	83.4	Confident	81.2	Confident	3 Å²	3	39.6 Å²	39.6	1%	0.012	22%	0.224	C	C	.	.	H	α-helix	trans	-65	-49	177.8	-177	-111.5	0	0	0	112.8	L291 R317 E318 F319 F323 T324 L325 Y395 S398 L399	L291-Y321 HydrophobicContact CD1-CD1 3.75Å; L291-Y321 HydrophobicContact CD1-CE1 3.61Å; R317-Y321 WeakPolarHBondContact O-CB 3.4Å; R317-Y321 PolarHBondContact O-N 2.89Å; E318-Y321 PolarHBondContact O-N 2.97Å; F319-Y321 VanDerWaalsContact C-N 3.31Å; F319-Y321 PolarHBondContact O-N 2.66Å; Y321-F323 VanDerWaalsContact C-N 3.31Å; Y321-F323 PolarHBondContact O-N 2.69Å; Y321-T324 WeakPolarHBondContact CA-OG1 3.29Å; Y321-T324 PolarHBondContact O-N 2.69Å; Y321-T324 PolarHBondContact O-OG1 2.73Å; Y321-L325 HydrophobicContact CD1-CD1 3.96Å; Y321-L325 HydrophobicContact CD2-CD1 4.4Å; Y321-L325 HydrophobicContact CD2-CG 4.48Å; Y321-L325 HydrophobicContact CE1-CD1 3.39Å; Y321-L325 HydrophobicContact CE1-CG 4.41Å; Y321-L325 HydrophobicContact CE2-CD1 3.85Å; Y321-L325 HydrophobicContact CE2-CG 4.13Å; Y321-L325 HydrophobicContact CG-CD1 4.46Å; Y321-L325 WeakPolarHBondContact O-CB 3.49Å; Y321-L325 WeakPolarHBondContact O-CG 3.28Å; Y321-L325 PolarHBondContact O-N 3.22Å; Y321-Y395 AromaticContact CD1-CD1 3.29Å; Y321-Y395 HydrophobicContact CD1-CD1 3.29Å; Y321-Y395 AromaticContact CD1-CE1 3.37Å; Y321-Y395 HydrophobicContact CD1-CE1 3.37Å; Y321-Y395 HydrophobicContact CD1-CG 4.45Å; Y321-Y395 AromaticContact CE1-CD1 3.34Å; Y321-Y395 HydrophobicContact CE1-CD1 3.34Å; Y321-Y395 AromaticContact CE1-CE1 3.36Å; Y321-Y395 HydrophobicContact CE1-CE1 3.36Å; Y321-Y395 HydrophobicContact CE1-CG 4.22Å; Y321-Y395 HydrophobicContact CG-CD1 4.11Å; Y321-S398 WeakPolarHBondContact CE2-OG 3.33Å; Y321-S398 WeakPolarHBondContact OH-CB 3.48Å; Y321-S398 PolarHBondContact OH-OG 3.44Å; Y321-L399 HydrophobicContact CD2-CB 4.17Å; Y321-L399 HydrophobicContact CD2-CD1 3.87Å; Y321-L399 HydrophobicContact CD2-CG 4.16Å; Y321-L399 HydrophobicContact CE2-CB 4.49Å; Y321-L399 HydrophobicContact CG-CD1 4.28Å
322	L	85.6	Confident	81.8	Confident	1 Å²	1	40 Å²	40	1%	0.005	22%	0.222	C	C	.	.	H	α-helix	trans	-58.9	-45.2	175	-85.3	170.9	0	0	0	111.6	L291 Y295 F312 E318 F319 L325 L326 F377 F380	L291-L322 HydrophobicContact CD1-CD2 3.37Å; L291-L322 HydrophobicContact CD1-CG 3.95Å; L291-L322 HydrophobicContact CD2-CD2 3.45Å; L291-L322 VanDerWaalsContact CD2-CD2 3.45Å; L291-L322 HydrophobicContact CG-CD2 4.03Å; Y295-L322 WeakPolarHBondContact OH-CD1 3.31Å; F312-L322 HydrophobicContact CB-CD1 3.81Å; F312-L322 HydrophobicContact CD1-CD1 3.45Å; F312-L322 VanDerWaalsContact CD1-CD1 3.45Å; F312-L322 HydrophobicContact CE1-CD1 4.15Å; F312-L322 HydrophobicContact CG-CD1 3.73Å; E318-L322 WeakPolarHBondContact O-CB 3.39Å; E318-L322 WeakPolarHBondContact O-CG 3.46Å; E318-L322 PolarHBondContact O-N 3.45Å; F319-L322 PolarHBondContact O-N 2.97Å; L322-L325 PolarHBondContact O-N 3.35Å; L322-L326 HydrophobicContact CD2-CD1 4.33Å; L322-L326 WeakPolarHBondContact O-CB 3.25Å; L322-L326 WeakPolarHBondContact O-CG 3.47Å; L322-L326 PolarHBondContact O-N 2.96Å; L322-F377 HydrophobicContact CB-CD2 4.39Å; L322-F377 HydrophobicContact CB-CE2 4.17Å; L322-F380 HydrophobicContact CD1-CB 4.22Å; L322-F380 HydrophobicContact CD2-CB 4.38Å; L322-F380 HydrophobicContact CD2-CD1 4.5Å; L322-F380 HydrophobicContact CD2-CD2 3.96Å; L322-F380 HydrophobicContact CD2-CE2 4.35Å; L322-F380 HydrophobicContact CD2-CG 4.04Å
323	F	87.4	Confident	82.3	Confident	59 Å²	59	41.6 Å²	41.6	26%	0.259	23%	0.233	S	C	.	.	H	α-helix	trans	-60	-53.9	179.2	-175.3	-89.4	0	0	0	110.4	F319 V320 Y321 L325 L326 F327 F332 I335 F377	F319-F323 WeakPolarHBondContact O-CB 3.42Å; F319-F323 PolarHBondContact O-N 3.47Å; V320-F323 PolarHBondContact O-N 3.32Å; Y321-F323 VanDerWaalsContact C-N 3.31Å; Y321-F323 PolarHBondContact O-N 2.69Å; F323-L325 VanDerWaalsContact C-N 3.31Å; F323-L325 PolarHBondContact O-N 3.01Å; F323-L326 PolarHBondContact O-N 2.89Å; F323-F327 HydrophobicContact CB-CD2 4.45Å; F323-F327 HydrophobicContact CD1-CD2 4.23Å; F323-F327 AromaticContact CD2-CD2 3.31Å; F323-F327 HydrophobicContact CD2-CD2 3.31Å; F323-F327 AromaticContact CD2-CE2 3.27Å; F323-F327 HydrophobicContact CD2-CE2 3.27Å; F323-F327 HydrophobicContact CD2-CG 4.28Å; F323-F327 HydrophobicContact CD2-CZ 4.21Å; F323-F327 HydrophobicContact CE1-CB 4.42Å; F323-F327 HydrophobicContact CE1-CD2 4.27Å; F323-F327 HydrophobicContact CE1-CG 4.41Å; F323-F327 HydrophobicContact CE2-CD1 4.45Å; F323-F327 AromaticContact CE2-CD2 3.37Å; F323-F327 HydrophobicContact CE2-CD2 3.37Å; F323-F327 HydrophobicContact CE2-CE1 4.37Å; F323-F327 AromaticContact CE2-CE2 3.26Å; F323-F327 HydrophobicContact CE2-CE2 3.26Å; F323-F327 AromaticContact CE2-CG 3.97Å; F323-F327 HydrophobicContact CE2-CG 3.97Å; F323-F327 AromaticContact CE2-CZ 3.77Å; F323-F327 HydrophobicContact CE2-CZ 3.77Å; F323-F327 AromaticContact CG-CD2 3.76Å; F323-F327 HydrophobicContact CG-CD2 3.76Å; F323-F327 HydrophobicContact CG-CE2 4.17Å; F323-F327 HydrophobicContact CZ-CB 4.48Å; F323-F327 AromaticContact CZ-CD2 3.86Å; F323-F327 HydrophobicContact CZ-CD2 3.86Å; F323-F327 HydrophobicContact CZ-CE2 4.14Å; F323-F327 HydrophobicContact CZ-CG 4.03Å; F323-F327 VanDerWaalsContact O-CB 3.28Å; F323-F327 WeakPolarHBondContact O-CB 3.42Å; F323-F327 WeakPolarHBondContact O-CD2 3.49Å; F323-F327 PolarHBondContact O-N 3.32Å; F323-F332 HydrophobicContact CZ-CE1 4.44Å; F323-I335 HydrophobicContact CE1-CD1 4.09Å; F323-F377 HydrophobicContact CB-CE2 3.98Å; F323-F377 HydrophobicContact CD2-CE2 4.25Å; F323-F377 HydrophobicContact CD2-CZ 4.48Å
324	T	86.3	Confident	82.9	Confident	30 Å²	30	41.8 Å²	41.8	18%	0.184	23%	0.229	C	C	.	.	H	α-helix	trans	-60	-39.1	-179.1	51.4	0	0	0	0	112.7	V320 Y321 G328 I335	V320-T324 HydrophobicContact CG1-CG2 4.26Å; V320-T324 WeakPolarHBondContact O-CB 3.25Å; V320-T324 VanDerWaalsContact O-CG2 3.23Å; V320-T324 WeakPolarHBondContact O-CG2 3.38Å; V320-T324 PolarHBondContact O-N 3.46Å; V320-T324 PolarHBondContact O-OG1 2.84Å; Y321-T324 WeakPolarHBondContact CA-OG1 3.29Å; Y321-T324 PolarHBondContact O-N 2.69Å; Y321-T324 PolarHBondContact O-OG1 2.73Å; T324-G328 VanDerWaalsContact O-CA 3.27Å; T324-G328 WeakPolarHBondContact O-CA 3.27Å; T324-G328 PolarHBondContact O-N 3.46Å; T324-I335 WeakPolarHBondContact O-CG2 3.4Å
325	L	87.1	Confident	83.8	Confident	3 Å²	3	39 Å²	39	2%	0.016	19%	0.192	C	C	.	.	H	α-helix	trans	-68.5	-51.8	176.9	-77.7	-178.2	0	0	0	113.3	L287 V288 L291 Y321 L322 F323 G328 L329 P402	L287-L325 HydrophobicContact CB-CD1 4.25Å; L287-L325 HydrophobicContact CB-CD2 3.71Å; L287-L325 HydrophobicContact CD1-CD2 3.93Å; L287-L325 HydrophobicContact CG-CD2 4.5Å; V288-L325 HydrophobicContact CG2-CB 4.01Å; V288-L325 HydrophobicContact CG2-CD1 4.39Å; V288-L325 HydrophobicContact CG2-CD2 4.42Å; L291-L325 HydrophobicContact CD1-CD1 4.31Å; Y321-L325 HydrophobicContact CD1-CD1 3.96Å; Y321-L325 HydrophobicContact CD2-CD1 4.4Å; Y321-L325 HydrophobicContact CD2-CG 4.48Å; Y321-L325 HydrophobicContact CE1-CD1 3.39Å; Y321-L325 HydrophobicContact CE1-CG 4.41Å; Y321-L325 HydrophobicContact CE2-CD1 3.85Å; Y321-L325 HydrophobicContact CE2-CG 4.13Å; Y321-L325 HydrophobicContact CG-CD1 4.46Å; Y321-L325 WeakPolarHBondContact O-CB 3.49Å; Y321-L325 WeakPolarHBondContact O-CG 3.28Å; Y321-L325 PolarHBondContact O-N 3.22Å; L322-L325 PolarHBondContact O-N 3.35Å; F323-L325 VanDerWaalsContact C-N 3.31Å; F323-L325 PolarHBondContact O-N 3.01Å; L325-G328 PolarHBondContact O-N 3.19Å; L325-L329 WeakPolarHBondContact O-CG 3.38Å; L325-L329 PolarHBondContact O-N 3.49Å; L325-P402 HydrophobicContact CD2-CB 4.48Å; L325-P402 HydrophobicContact CD2-CG 3.56Å; L325-P402 HydrophobicContact CG-CG 4.4Å
326	L	90	Very high	84.2	Confident	2 Å²	2	37.1 Å²	37.1	1%	0.01	18%	0.18	C	C	.	.	H	α-helix	trans	-73.2	-43.3	-173.2	-66.1	173.7	0	0	0	111.8	V288 L322 F323 G328 L329 S330 S373 L376 F377 F380	V288-L326 HydrophobicContact CG1-CD2 3.88Å; L322-L326 HydrophobicContact CD2-CD1 4.33Å; L322-L326 WeakPolarHBondContact O-CB 3.25Å; L322-L326 WeakPolarHBondContact O-CG 3.47Å; L322-L326 PolarHBondContact O-N 2.96Å; F323-L326 PolarHBondContact O-N 2.89Å; L326-G328 VanDerWaalsContact C-N 3.32Å; L326-L329 WeakPolarHBondContact O-CB 3.47Å; L326-L329 PolarHBondContact O-N 3.45Å; L326-S330 PolarHBondContact O-N 2.67Å; L326-S373 WeakPolarHBondContact O-CB 3.3Å; L326-L376 HydrophobicContact CD1-CB 4.45Å; L326-L376 HydrophobicContact CD2-CB 4.34Å; L326-F377 HydrophobicContact CD1-CB 3.89Å; L326-F377 HydrophobicContact CD1-CD2 4.14Å; L326-F380 HydrophobicContact CD1-CD2 3.76Å; L326-F380 HydrophobicContact CD1-CE2 3.81Å; L326-F380 HydrophobicContact CD2-CE2 4.18Å
327	F	90	Very high	84.7	Confident	5 Å²	5	30.1 Å²	30.1	2%	0.022	14%	0.143	C	C	.	.	H	α-helix	trans	-75.2	-24.4	175.3	-72.7	-85.4	0	0	0	112.6	F323 L329 S330 G331 F332 L374 F377 L439	F323-F327 HydrophobicContact CB-CD2 4.45Å; F323-F327 HydrophobicContact CD1-CD2 4.23Å; F323-F327 AromaticContact CD2-CD2 3.31Å; F323-F327 HydrophobicContact CD2-CD2 3.31Å; F323-F327 AromaticContact CD2-CE2 3.27Å; F323-F327 HydrophobicContact CD2-CE2 3.27Å; F323-F327 HydrophobicContact CD2-CG 4.28Å; F323-F327 HydrophobicContact CD2-CZ 4.21Å; F323-F327 HydrophobicContact CE1-CB 4.42Å; F323-F327 HydrophobicContact CE1-CD2 4.27Å; F323-F327 HydrophobicContact CE1-CG 4.41Å; F323-F327 HydrophobicContact CE2-CD1 4.45Å; F323-F327 AromaticContact CE2-CD2 3.37Å; F323-F327 HydrophobicContact CE2-CD2 3.37Å; F323-F327 HydrophobicContact CE2-CE1 4.37Å; F323-F327 AromaticContact CE2-CE2 3.26Å; F323-F327 HydrophobicContact CE2-CE2 3.26Å; F323-F327 AromaticContact CE2-CG 3.97Å; F323-F327 HydrophobicContact CE2-CG 3.97Å; F323-F327 AromaticContact CE2-CZ 3.77Å; F323-F327 HydrophobicContact CE2-CZ 3.77Å; F323-F327 AromaticContact CG-CD2 3.76Å; F323-F327 HydrophobicContact CG-CD2 3.76Å; F323-F327 HydrophobicContact CG-CE2 4.17Å; F323-F327 HydrophobicContact CZ-CB 4.48Å; F323-F327 AromaticContact CZ-CD2 3.86Å; F323-F327 HydrophobicContact CZ-CD2 3.86Å; F323-F327 HydrophobicContact CZ-CE2 4.14Å; F323-F327 HydrophobicContact CZ-CG 4.03Å; F323-F327 VanDerWaalsContact O-CB 3.28Å; F323-F327 WeakPolarHBondContact O-CB 3.42Å; F323-F327 WeakPolarHBondContact O-CD2 3.49Å; F323-F327 PolarHBondContact O-N 3.32Å; F327-L329 PolarHBondContact O-N 3.01Å; F327-S330 WeakPolarHBondContact CA-OG 3.21Å; F327-S330 PolarHBondContact O-N 3.49Å; F327-S330 PolarHBondContact O-OG 3.16Å; F327-G331 PolarHBondContact O-N 2.91Å; F327-F332 HydrophobicContact CB-CB 3.76Å; F327-F332 HydrophobicContact CB-CG 4.26Å; F327-F332 HydrophobicContact CD1-CB 4.22Å; F327-F332 AromaticContact CD1-CD2 3.95Å; F327-F332 HydrophobicContact CD1-CD2 3.95Å; F327-F332 HydrophobicContact CD1-CG 4.14Å; F327-F332 HydrophobicContact CG-CB 4.47Å; F327-F332 PolarHBondContact O-N 3.13Å; F327-L374 HydrophobicContact CE1-CD2 3.95Å; F327-L374 HydrophobicContact CE1-CG 3.91Å; F327-L374 HydrophobicContact CZ-CD2 3.43Å; F327-L374 VanDerWaalsContact CZ-CD2 3.43Å; F327-L374 HydrophobicContact CZ-CG 3.84Å; F327-F377 HydrophobicContact CE2-CB 4.32Å; F327-F377 HydrophobicContact CE2-CD2 4.15Å; F327-F377 HydrophobicContact CE2-CG 4.12Å; F327-L439 HydrophobicContact CE1-CD2 3.69Å; F327-L439 HydrophobicContact CZ-CD2 4.35Å
328	G	88.7	Confident	85.1	Confident	0 Å²	0	25.7 Å²	25.7	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-62	-30.8	168.7	0	0	0	0	0	113.2	T324 L325 L326 I335 M337	T324-G328 VanDerWaalsContact O-CA 3.27Å; T324-G328 WeakPolarHBondContact O-CA 3.27Å; T324-G328 PolarHBondContact O-N 3.46Å; L325-G328 PolarHBondContact O-N 3.19Å; L326-G328 VanDerWaalsContact C-N 3.32Å; G328-I335 VanDerWaalsContact CA-CG2 3.48Å; G328-M337 VanDerWaalsContact O-CB 3.27Å; G328-M337 WeakPolarHBondContact O-CB 3.42Å; G328-M337 WeakPolarHBondContact O-CG 3.27Å; G328-M337 PolarHBondContact O-N 2.62Å
329	L	88.7	Confident	85.3	Confident	3 Å²	3	25.9 Å²	25.9	2%	0.016	13%	0.127	C	C	.	.	H	α-helix	trans	-75.8	-35.5	175.2	-69.9	174	0	0	0	113.3	M251 S284 K285 V288 L325 L326 F327 G331 K341	M251-L329 HydrophobicContact CE-CD1 4.08Å; S284-L329 VanDerWaalsContact OG-CD2 3.23Å; S284-L329 WeakPolarHBondContact OG-CD2 3.26Å; K285-L329 HydrophobicContact CD-CD1 4Å; K285-L329 HydrophobicContact CD-CD2 3.92Å; K285-L329 HydrophobicContact CG-CD2 3.95Å; V288-L329 HydrophobicContact CG2-CD1 3.76Å; L325-L329 WeakPolarHBondContact O-CG 3.38Å; L325-L329 PolarHBondContact O-N 3.49Å; L326-L329 WeakPolarHBondContact O-CB 3.47Å; L326-L329 PolarHBondContact O-N 3.45Å; F327-L329 PolarHBondContact O-N 3.01Å; L329-G331 VanDerWaalsContact C-N 3.27Å; L329-K341 PolarHBondContact O-NZ 3.4Å
330	S	88.5	Confident	85.5	Confident	0 Å²	0	22 Å²	22	0%	0	11%	0.11	C	C	.	.	H	α-helix	trans	-73	-25	175.3	57.4	0	0	0	0	111.8	L326 F327 K341 S369 S373	L326-S330 PolarHBondContact O-N 2.67Å; F327-S330 WeakPolarHBondContact CA-OG 3.21Å; F327-S330 PolarHBondContact O-N 3.49Å; F327-S330 PolarHBondContact O-OG 3.16Å; S330-K341 PolarHBondContact O-NZ 3.45Å; S330-S369 WeakPolarHBondContact CB-O 3.37Å; S330-S369 PolarHBondContact O-OG 3.06Å; S330-S373 WeakPolarHBondContact CB-OG 3.46Å; S330-S373 PolarHBondContact OG-OG 3.28Å
331	G	84.2	Confident	85.7	Confident	0 Å²	0	18.4 Å²	18.4	0%	0	9%	0.088	C	C	.	.	T	Hydrogen-bonded Turn	trans	89.1	35.2	-178.5	0	0	0	0	0	111.7	F327 L329 Y338 Y435	F327-G331 PolarHBondContact O-N 2.91Å; L329-G331 VanDerWaalsContact C-N 3.27Å; G331-Y338 WeakPolarHBondContact O-CB 3.23Å; G331-Y338 WeakPolarHBondContact O-CD2 3.34Å; G331-Y435 WeakPolarHBondContact O-CE1 3.46Å; G331-Y435 PolarHBondContact O-OH 3.4Å
332	F	84.2	Confident	85.8	Confident	42 Å²	42	18.8 Å²	18.8	18%	0.184	9%	0.09	C	C	.	.			trans	-54.4	143.7	174.3	-163.4	-97.5	0	0	0	110.9	F323 F327 F334 I335 Y338 L439	F323-F332 HydrophobicContact CZ-CE1 4.44Å; F327-F332 HydrophobicContact CB-CB 3.76Å; F327-F332 HydrophobicContact CB-CG 4.26Å; F327-F332 HydrophobicContact CD1-CB 4.22Å; F327-F332 AromaticContact CD1-CD2 3.95Å; F327-F332 HydrophobicContact CD1-CD2 3.95Å; F327-F332 HydrophobicContact CD1-CG 4.14Å; F327-F332 HydrophobicContact CG-CB 4.47Å; F327-F332 PolarHBondContact O-N 3.13Å; F332-F334 PolarHBondContact O-N 3.21Å; F332-I335 HydrophobicContact CB-CD1 4.38Å; F332-I335 HydrophobicContact CD1-CD1 4.08Å; F332-I335 PolarHBondContact O-N 3.02Å; F332-Y338 WeakPolarHBondContact O-CB 3.32Å; F332-L439 HydrophobicContact CE2-CD1 3.77Å; F332-L439 HydrophobicContact CE2-CD2 4.32Å; F332-L439 HydrophobicContact CE2-CG 4.25Å; F332-L439 HydrophobicContact CZ-CD1 4.28Å
333	P	81.3	Confident	85.7	Confident	37 Å²	37	19 Å²	19	24%	0.24	9%	0.092	C	C	.	.	T	Hydrogen-bonded Turn	trans	-46.9	129.8	-171.5	15.8	-32.9	0	0	0	113.4	I335 Y338	P333-I335 VanDerWaalsContact C-N 3.28Å; P333-I335 PolarHBondContact O-N 3.38Å; P333-Y338 HydrophobicContact CB-CD2 4.43Å; P333-Y338 HydrophobicContact CB-CE2 4.2Å
334	F	77.9	Confident	85.7	Confident	126 Å²	126	16.2 Å²	16.2	55%	0.553	8%	0.08	S	C	*	.	T	Hydrogen-bonded Turn	trans	68	11.5	179.2	-48.1	-71.5	0	0	0	116.6	F332 Y338 L423	F332-F334 PolarHBondContact O-N 3.21Å; F334-Y338 HydrophobicContact CD1-CE1 4.31Å; F334-L423 HydrophobicContact CE1-CD1 4.14Å; F334-L423 HydrophobicContact CE1-CD2 3.76Å; F334-L423 HydrophobicContact CZ-CD1 4.49Å; F334-L423 HydrophobicContact CZ-CD2 4.16Å
335	I	83.1	Confident	85.7	Confident	31 Å²	31	15.3 Å²	15.3	16%	0.159	7%	0.074	C	C	.	.	S	Bend	trans	-117.7	130.8	178.8	-47.9	178.1	0	0	0	110.7	F323 T324 G328 F332 P333 M337 Y338	F323-I335 HydrophobicContact CE1-CD1 4.09Å; T324-I335 WeakPolarHBondContact O-CG2 3.4Å; G328-I335 VanDerWaalsContact CA-CG2 3.48Å; F332-I335 HydrophobicContact CB-CD1 4.38Å; F332-I335 HydrophobicContact CD1-CD1 4.08Å; F332-I335 PolarHBondContact O-N 3.02Å; P333-I335 VanDerWaalsContact C-N 3.28Å; P333-I335 PolarHBondContact O-N 3.38Å; I335-M337 PolarHBondContact O-N 3.46Å; I335-Y338 VanDerWaalsContact O-CB 3.3Å; I335-Y338 WeakPolarHBondContact O-CB 3.2Å; I335-Y338 PolarHBondContact O-N 3.37Å
336	C	83.2	Confident	85.4	Confident	2 Å²	2	15.6 Å²	15.6	1%	0.014	8%	0.076	C	C	.	.	T	Hydrogen-bonded Turn	trans	36.7	-98.6	171.6	-58.2	0	0	0	0	114.7	I280 Y338 S405	I280-C336 HydrophobicContact CG2-CB 3.84Å; C336-Y338 PolarHBondContact O-N 3.32Å; C336-S405 PolarHBondContact SG-OG 3.31Å
337	M	87.7	Confident	84.9	Confident	0 Å²	0	17 Å²	17	0%	0	9%	0.086	C	C	.	.	T	Hydrogen-bonded Turn	trans	-75.3	-6	-172.1	-60.6	-78.5	-74.7	0	0	114.4	Q277 I280 H281 G328 I335 F339 S340 K341	Q277-M337 VanDerWaalsContact CD-CE 3.49Å; Q277-M337 HydrophobicContact CG-CE 3.24Å; Q277-M337 HydrophobicContact CG-SD 3.97Å; I280-M337 HydrophobicContact CB-SD 3.87Å; I280-M337 HydrophobicContact CG2-CG 3.98Å; I280-M337 HydrophobicContact CG2-SD 3.64Å; H281-M337 HydrophobicContact CB-CE 3.99Å; H281-M337 HydrophobicContact CB-SD 4.02Å; G328-M337 VanDerWaalsContact O-CB 3.27Å; G328-M337 WeakPolarHBondContact O-CB 3.42Å; G328-M337 WeakPolarHBondContact O-CG 3.27Å; G328-M337 PolarHBondContact O-N 2.62Å; I335-M337 PolarHBondContact O-N 3.46Å; M337-F339 VanDerWaalsContact C-N 3.27Å; M337-F339 PolarHBondContact O-N 3.1Å; M337-S340 PolarHBondContact O-OG 3.48Å; M337-K341 PolarHBondContact O-N 2.9Å
338	Y	86.1	Confident	84.4	Confident	17 Å²	17	17 Å²	17	7%	0.067	9%	0.086	C	C	.	.	H	α-helix	trans	-53.6	-47.7	178.4	168.8	-109.7	0	0	0	111.6	G331 F332 P333 F334 I335 C336 K341 H342 L431 Y435	G331-Y338 WeakPolarHBondContact O-CB 3.23Å; G331-Y338 WeakPolarHBondContact O-CD2 3.34Å; F332-Y338 WeakPolarHBondContact O-CB 3.32Å; P333-Y338 HydrophobicContact CB-CD2 4.43Å; P333-Y338 HydrophobicContact CB-CE2 4.2Å; F334-Y338 HydrophobicContact CD1-CE1 4.31Å; I335-Y338 VanDerWaalsContact O-CB 3.3Å; I335-Y338 WeakPolarHBondContact O-CB 3.2Å; I335-Y338 PolarHBondContact O-N 3.37Å; C336-Y338 PolarHBondContact O-N 3.32Å; Y338-K341 PolarHBondContact O-N 3.46Å; Y338-H342 HydrophobicContact CD2-CB 4.44Å; Y338-H342 HydrophobicContact CE2-CB 4.17Å; Y338-H342 AromaticContact CZ-CD2 3.99Å; Y338-H342 WeakPolarHBondContact O-CB 3.28Å; Y338-H342 PolarHBondContact O-N 3.34Å; Y338-L431 HydrophobicContact CE2-CD2 4.32Å; Y338-Y435 HydrophobicContact CD2-CE2 4.14Å; Y338-Y435 HydrophobicContact CE2-CE2 4.15Å
339	F	82.5	Confident	83.4	Confident	25 Å²	25	18.7 Å²	18.7	11%	0.11	10%	0.104	C	C	.	.	H	α-helix	trans	-57.9	-53.8	-175.8	-72.5	-56.9	0	0	0	111.9	M337 H342 A343 Y410 L413	M337-F339 VanDerWaalsContact C-N 3.27Å; M337-F339 PolarHBondContact O-N 3.1Å; F339-H342 PolarHBondContact O-N 3.38Å; F339-A343 VanDerWaalsContact O-CB 3.31Å; F339-A343 WeakPolarHBondContact O-CB 3.34Å; F339-A343 PolarHBondContact O-N 3.22Å; F339-Y410 HydrophobicContact CD1-CD2 4.2Å; F339-Y410 AromaticContact CE1-CD2 3.57Å; F339-Y410 HydrophobicContact CE1-CD2 3.57Å; F339-Y410 HydrophobicContact CE1-CE2 4.37Å; F339-Y410 HydrophobicContact CE1-CG 4.46Å; F339-Y410 AromaticContact CZ-CD2 3.81Å; F339-Y410 HydrophobicContact CZ-CD2 3.81Å; F339-Y410 HydrophobicContact CZ-CG 4.33Å; F339-L413 HydrophobicContact CB-CD1 3.37Å; F339-L413 HydrophobicContact CB-CG 4.02Å; F339-L413 HydrophobicContact CD1-CD1 3.85Å; F339-L413 HydrophobicContact CG-CD1 3.99Å; F339-L413 WeakPolarHBondContact O-CD1 3.49Å
340	S	86.4	Confident	82.2	Confident	0 Å²	0	21.9 Å²	21.9	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-64.5	-45.4	-178.7	63.9	0	0	0	0	112.6	Q277 M337 F344	Q277-S340 PolarHBondContact OE1-OG 3.3Å; M337-S340 PolarHBondContact O-OG 3.48Å; S340-F344 VanDerWaalsContact O-CB 3.3Å; S340-F344 WeakPolarHBondContact O-CB 2.69Å; S340-F344 PolarHBondContact O-N 3.27Å
341	K	88.6	Confident	80.8	Confident	0 Å²	0	28.2 Å²	28.2	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-65.5	-42.2	180	-70.1	-175.4	-177	174.7	0	111.7	N258 W261 L329 S330 M337 Y338 I345	N258-K341 PolarHBondContact OD1-NZ 3.01Å; W261-K341 HydrophobicContact CE3-CG 4.45Å; L329-K341 PolarHBondContact O-NZ 3.4Å; S330-K341 PolarHBondContact O-NZ 3.45Å; M337-K341 PolarHBondContact O-N 2.9Å; Y338-K341 PolarHBondContact O-N 3.46Å; K341-I345 WeakPolarHBondContact O-CB 3.48Å; K341-I345 WeakPolarHBondContact O-CD1 3.29Å; K341-I345 VanDerWaalsContact O-CG1 3.26Å; K341-I345 WeakPolarHBondContact O-CG1 3.42Å; K341-I345 PolarHBondContact O-N 2.88Å
342	H	85	Confident	79.6	Confident	11 Å²	11	37.2 Å²	37.2	5%	0.051	20%	0.202	C	C	.	.	H	α-helix	trans	-64.5	-49.6	178.2	-179.2	-79.7	0	0	0	111.5	Y338 F339 F344 I345 S346 S428 L431	Y338-H342 HydrophobicContact CD2-CB 4.44Å; Y338-H342 HydrophobicContact CE2-CB 4.17Å; Y338-H342 AromaticContact CZ-CD2 3.99Å; Y338-H342 WeakPolarHBondContact O-CB 3.28Å; Y338-H342 PolarHBondContact O-N 3.34Å; F339-H342 PolarHBondContact O-N 3.38Å; H342-F344 VanDerWaalsContact C-N 3.28Å; H342-F344 PolarHBondContact O-N 2.93Å; H342-I345 PolarHBondContact O-N 3.18Å; H342-S346 WeakPolarHBondContact O-CB 3.39Å; H342-S346 PolarHBondContact O-N 3.11Å; H342-S428 VanDerWaalsContact NE2-CA 3.31Å; H342-S428 WeakPolarHBondContact NE2-CA 3.49Å; H342-S428 WeakPolarHBondContact NE2-CB 3.35Å; H342-L431 HydrophobicContact CB-CD2 3.92Å
343	A	82.7	Confident	78.2	Confident	6 Å²	6	41.1 Å²	41.1	5%	0.05	23%	0.228	C	C	.	.	H	α-helix	trans	-57.7	-43.2	178.2	0	0	0	0	0	111.5	L273 F339 S346 S347 L413	L273-A343 HydrophobicContact CD1-CB 4.27Å; L273-A343 HydrophobicContact CD2-CB 3.93Å; F339-A343 VanDerWaalsContact O-CB 3.31Å; F339-A343 WeakPolarHBondContact O-CB 3.34Å; F339-A343 PolarHBondContact O-N 3.22Å; A343-S346 PolarHBondContact O-N 2.97Å; A343-S347 PolarHBondContact O-N 2.93Å; A343-L413 HydrophobicContact CB-CD1 4.22Å; A343-L413 HydrophobicContact CB-CD2 3.76Å
344	F	87.1	Confident	76.9	Confident	0 Å²	0	48.8 Å²	48.8	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-67.2	-45.5	179.2	-179.4	-116.2	0	0	0	113.9	W261 V264 M265 L268 E270 L273 S340 H342 S346 S347 I348 M362	W261-F344 HydrophobicContact CE3-CD1 4.26Å; W261-F344 HydrophobicContact CE3-CE1 4.43Å; W261-F344 AromaticContact CZ3-CD1 3.99Å; W261-F344 HydrophobicContact CZ3-CD1 3.99Å; W261-F344 HydrophobicContact CZ3-CE1 4.31Å; V264-F344 HydrophobicContact CG1-CE1 3.93Å; V264-F344 HydrophobicContact CG1-CZ 3.73Å; M265-F344 HydrophobicContact CB-CD2 4.3Å; M265-F344 HydrophobicContact CB-CE2 4.03Å; M265-F344 HydrophobicContact CB-CZ 4.3Å; M265-F344 HydrophobicContact CE-CB 3.58Å; M265-F344 HydrophobicContact CE-CD1 3.81Å; M265-F344 HydrophobicContact CE-CD2 4.46Å; M265-F344 HydrophobicContact CE-CG 3.71Å; M265-F344 HydrophobicContact CG-CB 4.44Å; M265-F344 HydrophobicContact CG-CD1 3.94Å; M265-F344 HydrophobicContact CG-CD2 3.64Å; M265-F344 HydrophobicContact CG-CE1 3.94Å; M265-F344 HydrophobicContact CG-CE2 3.67Å; M265-F344 HydrophobicContact CG-CG 3.75Å; M265-F344 HydrophobicContact CG-CZ 3.77Å; M265-F344 HydrophobicContact SD-CG 4.43Å; L268-F344 HydrophobicContact CB-CE2 4.25Å; L268-F344 HydrophobicContact CB-CZ 4.5Å; L268-F344 HydrophobicContact CD1-CE1 4.44Å; L268-F344 HydrophobicContact CD1-CE2 3.81Å; L268-F344 HydrophobicContact CD1-CZ 3.42Å; L268-F344 VanDerWaalsContact CD1-CZ 3.42Å; L268-F344 HydrophobicContact CG-CZ 4.39Å; E270-F344 HydrophobicContact CB-CD2 4.28Å; E270-F344 HydrophobicContact CB-CE2 4.34Å; E270-F344 HydrophobicContact CG-CD2 4.08Å; E270-F344 HydrophobicContact CG-CE2 4.12Å; L273-F344 HydrophobicContact CD1-CB 4.14Å; L273-F344 HydrophobicContact CD1-CD2 4.45Å; S340-F344 VanDerWaalsContact O-CB 3.3Å; S340-F344 WeakPolarHBondContact O-CB 2.69Å; S340-F344 PolarHBondContact O-N 3.27Å; H342-F344 VanDerWaalsContact C-N 3.28Å; H342-F344 PolarHBondContact O-N 2.93Å; F344-S346 PolarHBondContact O-N 3.47Å; F344-S347 PolarHBondContact O-N 2.76Å; F344-S347 PolarHBondContact O-OG 3.25Å; F344-S347 VanDerWaalsContact O-OG 3.11Å; F344-I348 HydrophobicContact CD1-CD1 3.67Å; F344-I348 HydrophobicContact CD2-CD1 4.15Å; F344-I348 HydrophobicContact CD2-CG1 4.43Å; F344-I348 HydrophobicContact CE1-CD1 3.24Å; F344-I348 HydrophobicContact CE1-CG1 4.41Å; F344-I348 HydrophobicContact CE2-CD1 3.76Å; F344-I348 HydrophobicContact CE2-CG1 4.11Å; F344-I348 HydrophobicContact CG-CD1 4.13Å; F344-I348 HydrophobicContact CZ-CD1 3.32Å; F344-I348 HydrophobicContact CZ-CG1 4.15Å; F344-I348 WeakPolarHBondContact O-CG1 3.07Å; F344-I348 PolarHBondContact O-N 3.15Å; F344-M362 HydrophobicContact CE1-CE 3.94Å
345	I	86.5	Confident	76.7	Confident	11 Å²	11	45.6 Å²	45.6	6%	0.056	24%	0.244	C	C	.	.	H	α-helix	trans	-62.3	-36.8	176.8	-69.9	167.2	0	0	0	110.1	W261 K341 H342 G349 M363 V366 L431	W261-I345 HydrophobicContact CH2-CD1 4.15Å; W261-I345 HydrophobicContact CH2-CG1 4.47Å; W261-I345 HydrophobicContact CZ3-CD1 4.43Å; W261-I345 HydrophobicContact CZ3-CG1 4.4Å; K341-I345 WeakPolarHBondContact O-CB 3.48Å; K341-I345 WeakPolarHBondContact O-CD1 3.29Å; K341-I345 VanDerWaalsContact O-CG1 3.26Å; K341-I345 WeakPolarHBondContact O-CG1 3.42Å; K341-I345 PolarHBondContact O-N 2.88Å; H342-I345 PolarHBondContact O-N 3.18Å; I345-G349 PolarHBondContact O-N 3.49Å; I345-G349 VanDerWaalsContact O-N 3.11Å; I345-M363 HydrophobicContact CD1-SD 3.98Å; I345-M363 HydrophobicContact CG2-SD 3.79Å; I345-V366 HydrophobicContact CD1-CG2 3.79Å; I345-L431 HydrophobicContact CD1-CD1 3.53Å
346	S	80.2	Confident	76.5	Confident	10 Å²	10	47.9 Å²	47.9	7%	0.07	26%	0.259	C	S	.	.	H	α-helix	trans	-65.4	-43.4	176	-175.9	0	0	0	0	112.4	H342 A343 F344 I348 G349 Q427	H342-S346 WeakPolarHBondContact O-CB 3.39Å; H342-S346 PolarHBondContact O-N 3.11Å; A343-S346 PolarHBondContact O-N 2.97Å; F344-S346 PolarHBondContact O-N 3.47Å; S346-I348 PolarHBondContact O-N 3.06Å; S346-G349 PolarHBondContact O-N 3.33Å; S346-Q427 VanDerWaalsContact CB-OE1 3.31Å; S346-Q427 PolarHBondContact O-NE2 3.04Å; S346-Q427 PolarHBondContact O-OE1 3.42Å; S346-Q427 PolarHBondContact OG-OE1 3.49Å
347	S	79.8	Confident	76.6	Confident	31 Å²	31	51.8 Å²	51.8	22%	0.217	29%	0.286	C	S	.	.	H	α-helix	trans	-63.7	-40.7	178.6	83.6	0	0	0	0	111.8	E270 A343 F344 G349 Y351	E270-S347 WeakPolarHBondContact OE1-CB 3.42Å; E270-S347 PolarHBondContact OE1-OG 3.33Å; A343-S347 PolarHBondContact O-N 2.93Å; F344-S347 PolarHBondContact O-N 2.76Å; F344-S347 PolarHBondContact O-OG 3.25Å; F344-S347 VanDerWaalsContact O-OG 3.11Å; S347-G349 PolarHBondContact O-N 3.15Å; S347-Y351 WeakPolarHBondContact O-CD2 3.37Å; S347-Y351 WeakPolarHBondContact O-CE2 3.33Å
348	I	80.2	Confident	76.6	Confident	5 Å²	5	53 Å²	53	3%	0.026	29%	0.292	C	S	.	.	H	α-helix	trans	-68.3	-35.9	178.3	-61	162	0	0	0	112.3	L268 F344 S346 G350 Y351 K355 L358 V359	L268-I348 HydrophobicContact CD1-CD1 3.65Å; L268-I348 HydrophobicContact CD1-CG1 3.77Å; F344-I348 HydrophobicContact CD1-CD1 3.67Å; F344-I348 HydrophobicContact CD2-CD1 4.15Å; F344-I348 HydrophobicContact CD2-CG1 4.43Å; F344-I348 HydrophobicContact CE1-CD1 3.24Å; F344-I348 HydrophobicContact CE1-CG1 4.41Å; F344-I348 HydrophobicContact CE2-CD1 3.76Å; F344-I348 HydrophobicContact CE2-CG1 4.11Å; F344-I348 HydrophobicContact CG-CD1 4.13Å; F344-I348 HydrophobicContact CZ-CD1 3.32Å; F344-I348 HydrophobicContact CZ-CG1 4.15Å; F344-I348 WeakPolarHBondContact O-CG1 3.07Å; F344-I348 PolarHBondContact O-N 3.15Å; S346-I348 PolarHBondContact O-N 3.06Å; I348-G350 PolarHBondContact O-N 2.93Å; I348-Y351 WeakPolarHBondContact O-CD2 3.49Å; I348-Y351 PolarHBondContact O-N 2.99Å; I348-K355 HydrophobicContact CG2-CB 4.06Å; I348-K355 HydrophobicContact CG2-CD 4.46Å; I348-K355 HydrophobicContact CG2-CG 4.42Å; I348-L358 HydrophobicContact CD1-CD2 3.81Å; I348-L358 HydrophobicContact CG2-CD2 3.84Å; I348-V359 HydrophobicContact CB-CG2 4.19Å; I348-V359 HydrophobicContact CG2-CG2 3.46Å; I348-V359 VanDerWaalsContact CG2-CG2 3.46Å
349	G	67.9	Low	76.6	Confident	36 Å²	36	53.7 Å²	53.7	37%	0.371	30%	0.298	S	S	.	.	H	α-helix	trans	-66.5	-11.8	-172	0	0	0	0	0	114.7	I345 S346 S347 Y351 Q427	I345-G349 PolarHBondContact O-N 3.49Å; I345-G349 VanDerWaalsContact O-N 3.11Å; S346-G349 PolarHBondContact O-N 3.33Å; S347-G349 PolarHBondContact O-N 3.15Å; G349-Y351 VanDerWaalsContact C-N 3.32Å; G349-Q427 VanDerWaalsContact CA-NE2 3.3Å
350	G	63.6	Low	76.9	Confident	70 Å²	70	57.7 Å²	57.7	72%	0.722	32%	0.319	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80	-3.2	175.4	0	0	0	0	0	115.6	I348	I348-G350 PolarHBondContact O-N 2.93Å
351	Y	58.4	Low	77.1	Confident	132 Å²	132	59.3 Å²	59.3	52%	0.518	33%	0.329	S	S	.	.	S	Bend	trans	-113	164.3	-168.3	-62.3	-84.8	0	0	0	115	S347 I348 G349 K355	S347-Y351 WeakPolarHBondContact O-CD2 3.37Å; S347-Y351 WeakPolarHBondContact O-CE2 3.33Å; I348-Y351 WeakPolarHBondContact O-CD2 3.49Å; I348-Y351 PolarHBondContact O-N 2.99Å; G349-Y351 VanDerWaalsContact C-N 3.32Å; Y351-K355 HydrophobicContact CD1-CD 4.44Å; Y351-K355 HydrophobicContact CD2-CD 3.89Å; Y351-K355 HydrophobicContact CG-CD 3.64Å
352	K	58.6	Low	77.3	Confident	190 Å²	190	59.4 Å²	59.4	83%	0.826	33%	0.33	S	S	*	.			trans	-44.5	161.9	-175.2	-61.1	179.2	-178.9	177	0	116.5	F354 K355	K352-F354 VanDerWaalsContact C-N 3.33Å; K352-F354 PolarHBondContact O-N 3.27Å; K352-K355 WeakPolarHBondContact O-CB 3.36Å; K352-K355 PolarHBondContact O-N 3.05Å
353	V	54.8	Low	77.5	Confident	123 Å²	123	59.6 Å²	59.6	75%	0.745	33%	0.331	S	S	*	.	T	Hydrogen-bonded Turn	trans	-39.9	-42.3	-177.5	-176.4	0	0	0	0	116.2	K355 V356	V353-K355 PolarHBondContact O-N 2.91Å; V353-V356 WeakPolarHBondContact O-CB 3.4Å; V353-V356 WeakPolarHBondContact O-CG2 3.46Å; V353-V356 PolarHBondContact O-N 3.03Å
354	F	55.8	Low	78	Confident	198 Å²	198	63.4 Å²	63.4	87%	0.868	35%	0.35	S	S	*	.	H	α-helix	trans	-60.5	-30.9	178.1	-86.4	-77.9	0	0	0	113.4	K352 V356	K352-F354 VanDerWaalsContact C-N 3.33Å; K352-F354 PolarHBondContact O-N 3.27Å; F354-V356 VanDerWaalsContact C-N 3.27Å; F354-V356 PolarHBondContact O-N 3.13Å
355	K	72.8	Confident	78.2	Confident	60 Å²	60	63.6 Å²	63.6	26%	0.261	35%	0.351	S	S	.	.	H	α-helix	trans	-76.3	-14	174.5	-74.5	173	172.2	-168.9	0	112.4	I348 Y351 K352 V353 L358 V359	I348-K355 HydrophobicContact CG2-CB 4.06Å; I348-K355 HydrophobicContact CG2-CD 4.46Å; I348-K355 HydrophobicContact CG2-CG 4.42Å; Y351-K355 HydrophobicContact CD1-CD 4.44Å; Y351-K355 HydrophobicContact CD2-CD 3.89Å; Y351-K355 HydrophobicContact CG-CD 3.64Å; K352-K355 WeakPolarHBondContact O-CB 3.36Å; K352-K355 PolarHBondContact O-N 3.05Å; V353-K355 PolarHBondContact O-N 2.91Å; K355-L358 PolarHBondContact O-N 3.37Å; K355-V359 WeakPolarHBondContact O-CG2 3.39Å; K355-V359 PolarHBondContact O-N 3.2Å
356	V	78.3	Confident	78.5	Confident	78 Å²	78	63.1 Å²	63.1	47%	0.473	35%	0.349	S	S	.	.	H	α-helix	trans	-66.3	-45.2	174.1	-179.3	0	0	0	0	111.2	V353 F354 L358 V359 I360	V353-V356 WeakPolarHBondContact O-CB 3.4Å; V353-V356 WeakPolarHBondContact O-CG2 3.46Å; V353-V356 PolarHBondContact O-N 3.03Å; F354-V356 VanDerWaalsContact C-N 3.27Å; F354-V356 PolarHBondContact O-N 3.13Å; V356-L358 VanDerWaalsContact C-N 3.3Å; V356-L358 PolarHBondContact O-N 3.37Å; V356-V359 PolarHBondContact O-N 2.9Å; V356-I360 HydrophobicContact CG1-CD1 4.09Å; V356-I360 WeakPolarHBondContact O-CG1 3.29Å; V356-I360 PolarHBondContact O-N 2.87Å
357	C	84.9	Confident	79.1	Confident	84 Å²	84	64.5 Å²	64.5	57%	0.568	36%	0.355	S	S	*	.	H	α-helix	trans	-59.7	-44.8	175.3	-176.8	0	0	0	0	110.9	V359 I360 V361	C357-V359 PolarHBondContact O-N 3.29Å; C357-I360 PolarHBondContact O-N 3.34Å; C357-V361 WeakPolarHBondContact O-CG2 3.29Å; C357-V361 PolarHBondContact O-N 3.28Å
358	L	87.9	Confident	79.7	Confident	25 Å²	25	64 Å²	64	13%	0.131	35%	0.35	C	S	.	.	H	α-helix	trans	-58.9	-47.7	175.6	-173.8	149.1	0	0	0	111.3	M227 L268 I348 K355 V356 I360 V361 M362	M227-L358 HydrophobicContact CE-CD1 3.31Å; M227-L358 HydrophobicContact CE-CD2 4.47Å; M227-L358 HydrophobicContact CE-CG 3.88Å; M227-L358 HydrophobicContact CG-CD1 4.48Å; M227-L358 HydrophobicContact SD-CD1 4.27Å; L268-L358 HydrophobicContact CD1-CD1 4.47Å; L268-L358 HydrophobicContact CD1-CD2 4.13Å; I348-L358 HydrophobicContact CD1-CD2 3.81Å; I348-L358 HydrophobicContact CG2-CD2 3.84Å; K355-L358 PolarHBondContact O-N 3.37Å; V356-L358 VanDerWaalsContact C-N 3.3Å; V356-L358 PolarHBondContact O-N 3.37Å; L358-I360 PolarHBondContact O-N 3.36Å; L358-V361 PolarHBondContact O-N 3.27Å; L358-M362 HydrophobicContact CD2-CG 3.94Å; L358-M362 HydrophobicContact CG-CG 4.48Å; L358-M362 VanDerWaalsContact O-CG 3.24Å; L358-M362 WeakPolarHBondContact O-CG 3.48Å; L358-M362 PolarHBondContact O-N 3.41Å
359	V	86.6	Confident	80.3	Confident	32 Å²	32	63.8 Å²	63.8	19%	0.194	35%	0.349	C	S	.	.	H	α-helix	trans	-56.7	-48.4	175.9	170.2	0	0	0	0	110.8	I348 K355 V356 C357 V361 M362 M363	I348-V359 HydrophobicContact CB-CG2 4.19Å; I348-V359 HydrophobicContact CG2-CG2 3.46Å; I348-V359 VanDerWaalsContact CG2-CG2 3.46Å; K355-V359 WeakPolarHBondContact O-CG2 3.39Å; K355-V359 PolarHBondContact O-N 3.2Å; V356-V359 PolarHBondContact O-N 2.9Å; C357-V359 PolarHBondContact O-N 3.29Å; V359-V361 VanDerWaalsContact C-N 3.31Å; V359-V361 PolarHBondContact O-N 3.34Å; V359-M362 PolarHBondContact O-N 3.27Å; V359-M362 VanDerWaalsContact O-N 3.12Å; V359-M363 HydrophobicContact CG1-CG 4.14Å; V359-M363 VanDerWaalsContact O-CG 3.26Å; V359-M363 WeakPolarHBondContact O-CG 3.43Å; V359-M363 PolarHBondContact O-N 3.44Å
360	I	88.5	Confident	81.4	Confident	109 Å²	109	62.1 Å²	62.1	56%	0.559	33%	0.331	S	S	*	.	H	α-helix	trans	-57.2	-45.8	178.9	-66.9	164.9	0	0	0	111	V356 C357 L358 M363 L364	V356-I360 HydrophobicContact CG1-CD1 4.09Å; V356-I360 WeakPolarHBondContact O-CG1 3.29Å; V356-I360 PolarHBondContact O-N 2.87Å; C357-I360 PolarHBondContact O-N 3.34Å; L358-I360 PolarHBondContact O-N 3.36Å; I360-M363 PolarHBondContact O-N 3.06Å; I360-L364 PolarHBondContact O-N 2.64Å
361	V	91.8	Very high	82.7	Confident	35 Å²	35	58.9 Å²	58.9	21%	0.212	30%	0.298	C	S	.	.	H	α-helix	trans	-63.6	-43.3	177.3	177.9	0	0	0	0	111	L231 L235 C357 L358 V359 M363 L364 C365	L231-V361 HydrophobicContact CD2-CG1 3.84Å; L235-V361 HydrophobicContact CD1-CG1 4.15Å; L235-V361 HydrophobicContact CD2-CG1 4.49Å; C357-V361 WeakPolarHBondContact O-CG2 3.29Å; C357-V361 PolarHBondContact O-N 3.28Å; L358-V361 PolarHBondContact O-N 3.27Å; V359-V361 VanDerWaalsContact C-N 3.31Å; V359-V361 PolarHBondContact O-N 3.34Å; V361-M363 PolarHBondContact O-N 3.22Å; V361-L364 WeakPolarHBondContact O-CB 3.49Å; V361-L364 PolarHBondContact O-N 3.16Å; V361-C365 PolarHBondContact O-N 2.95Å; V361-C365 PolarHBondContact O-SG 3.2Å
362	M	91.4	Very high	84.2	Confident	1 Å²	1	52.8 Å²	52.8	1%	0.005	27%	0.274	C	S	.	.	H	α-helix	trans	-63.6	-39.8	177.4	-64	-49.5	-78.9	0	0	111.9	L231 M234 W261 V264 F344 L358 V359 L364 C365 V366	L231-M362 HydrophobicContact CD2-SD 3.49Å; L231-M362 WeakPolarHBondContact CD2-SD 3.39Å; M234-M362 HydrophobicContact CE-CE 3.84Å; M234-M362 HydrophobicContact CE-SD 3.68Å; M234-M362 HydrophobicContact SD-CE 4.12Å; W261-M362 HydrophobicContact CD2-CE 3.64Å; W261-M362 HydrophobicContact CE3-CE 3.2Å; W261-M362 HydrophobicContact CH2-CB 3.89Å; W261-M362 HydrophobicContact CH2-CE 3.42Å; W261-M362 VanDerWaalsContact CH2-CE 3.42Å; W261-M362 HydrophobicContact CH2-SD 4.48Å; W261-M362 HydrophobicContact CZ2-CE 3.84Å; W261-M362 WeakPolarHBondContact CZ2-O 3.33Å; W261-M362 HydrophobicContact CZ3-CB 4.44Å; W261-M362 HydrophobicContact CZ3-CE 3.1Å; V264-M362 HydrophobicContact CB-CE 4.33Å; V264-M362 HydrophobicContact CG1-CE 3.77Å; V264-M362 HydrophobicContact CG1-SD 4.16Å; F344-M362 HydrophobicContact CE1-CE 3.94Å; L358-M362 HydrophobicContact CD2-CG 3.94Å; L358-M362 HydrophobicContact CG-CG 4.48Å; L358-M362 VanDerWaalsContact O-CG 3.24Å; L358-M362 WeakPolarHBondContact O-CG 3.48Å; L358-M362 PolarHBondContact O-N 3.41Å; V359-M362 PolarHBondContact O-N 3.27Å; V359-M362 VanDerWaalsContact O-N 3.12Å; M362-L364 VanDerWaalsContact C-N 3.31Å; M362-L364 PolarHBondContact O-N 3.02Å; M362-C365 WeakPolarHBondContact O-CB 3.36Å; M362-C365 PolarHBondContact O-N 2.96Å; M362-C365 VanDerWaalsContact O-N 3.17Å; M362-V366 WeakPolarHBondContact O-CG2 3.29Å; M362-V366 PolarHBondContact O-N 2.98Å
363	M	90.2	Very high	85.7	Confident	16 Å²	16	43.8 Å²	43.8	8%	0.079	24%	0.235	C	C	.	.	H	α-helix	trans	-62.2	-40.2	173.9	-64.1	-45.7	-66.4	0	0	111.4	I345 V359 I360 V361 C365 V366 L367 L430 L431 V434	I345-M363 HydrophobicContact CD1-SD 3.98Å; I345-M363 HydrophobicContact CG2-SD 3.79Å; V359-M363 HydrophobicContact CG1-CG 4.14Å; V359-M363 VanDerWaalsContact O-CG 3.26Å; V359-M363 WeakPolarHBondContact O-CG 3.43Å; V359-M363 PolarHBondContact O-N 3.44Å; I360-M363 PolarHBondContact O-N 3.06Å; V361-M363 PolarHBondContact O-N 3.22Å; M363-C365 VanDerWaalsContact C-N 3.33Å; M363-V366 PolarHBondContact O-N 2.9Å; M363-L367 PolarHBondContact O-N 3.02Å; M363-L430 HydrophobicContact CE-CD2 3.34Å; M363-L430 HydrophobicContact CG-CD2 4.09Å; M363-L430 HydrophobicContact SD-CD2 4.05Å; M363-L431 HydrophobicContact CE-CB 4.31Å; M363-L431 HydrophobicContact CE-CD1 3.43Å; M363-L431 VanDerWaalsContact CE-CD1 3.43Å; M363-L431 HydrophobicContact CE-CG 4.44Å; M363-L431 HydrophobicContact SD-CD1 4.14Å; M363-V434 HydrophobicContact CB-CG2 4.48Å; M363-V434 HydrophobicContact CE-CB 3.79Å; M363-V434 HydrophobicContact CE-CG1 4.15Å; M363-V434 HydrophobicContact CE-CG2 3.46Å; M363-V434 VanDerWaalsContact CE-CG2 3.46Å
364	L	92	Very high	87.3	Confident	85 Å²	85	38 Å²	38	45%	0.445	20%	0.2	S	C	.	.	H	α-helix	trans	-64.3	-38.7	174.2	-169.8	148.6	0	0	0	111.5	L235 I360 V361 M362 L367 L368	L235-L364 HydrophobicContact CD2-CD2 3.33Å; I360-L364 PolarHBondContact O-N 2.64Å; V361-L364 WeakPolarHBondContact O-CB 3.49Å; V361-L364 PolarHBondContact O-N 3.16Å; M362-L364 VanDerWaalsContact C-N 3.31Å; M362-L364 PolarHBondContact O-N 3.02Å; L364-L367 WeakPolarHBondContact O-CB 3.39Å; L364-L367 PolarHBondContact O-N 3.46Å; L364-L368 HydrophobicContact CD2-CD1 3.72Å; L364-L368 HydrophobicContact CD2-CG 4.14Å; L364-L368 WeakPolarHBondContact O-CG 3.28Å; L364-L368 PolarHBondContact O-N 3.01Å
365	C	93.2	Very high	88.7	Confident	5 Å²	5	29.6 Å²	29.6	3%	0.034	16%	0.162	C	C	.	.	H	α-helix	trans	-63.7	-38.3	173.2	-67.9	0	0	0	0	112.5	W261 V361 M362 M363 L368 S369	W261-C365 HydrophobicContact CZ2-CB 3.71Å; V361-C365 PolarHBondContact O-N 2.95Å; V361-C365 PolarHBondContact O-SG 3.2Å; M362-C365 WeakPolarHBondContact O-CB 3.36Å; M362-C365 PolarHBondContact O-N 2.96Å; M362-C365 VanDerWaalsContact O-N 3.17Å; M363-C365 VanDerWaalsContact C-N 3.33Å; C365-L368 PolarHBondContact O-N 3.06Å; C365-S369 PolarHBondContact O-N 3.23Å
366	V	92.5	Very high	89.3	Confident	0 Å²	0	26.9 Å²	26.9	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-62.2	-47.2	172.4	176.2	0	0	0	0	109.9	W261 I345 M362 M363 L368 S369 V370 L431 V434 Y435	W261-V366 HydrophobicContact CH2-CG2 3.53Å; W261-V366 HydrophobicContact CZ2-CG2 3.55Å; I345-V366 HydrophobicContact CD1-CG2 3.79Å; M362-V366 WeakPolarHBondContact O-CG2 3.29Å; M362-V366 PolarHBondContact O-N 2.98Å; M363-V366 PolarHBondContact O-N 2.9Å; V366-L368 PolarHBondContact O-N 3.46Å; V366-S369 WeakPolarHBondContact O-CA 3.42Å; V366-S369 WeakPolarHBondContact O-CB 3.27Å; V366-S369 PolarHBondContact O-N 3.06Å; V366-S369 PolarHBondContact O-OG 3.3Å; V366-V370 WeakPolarHBondContact O-CG2 3.49Å; V366-V370 PolarHBondContact O-N 3.37Å; V366-V370 VanDerWaalsContact O-N 3.11Å; V366-L431 HydrophobicContact CG1-CD1 4.12Å; V366-L431 HydrophobicContact CG2-CD1 4.27Å; V366-V434 HydrophobicContact CB-CG1 4.35Å; V366-V434 HydrophobicContact CG1-CG1 4.23Å; V366-Y435 HydrophobicContact CG1-CD1 4.1Å; V366-Y435 HydrophobicContact CG1-CE1 3.46Å; V366-Y435 VanDerWaalsContact CG1-CE1 3.46Å
367	L	92.9	Very high	89.6	Confident	40 Å²	40	23.7 Å²	23.7	21%	0.209	13%	0.131	C	C	.	.	H	α-helix	trans	-55.8	-50.3	177.2	-174.7	150.6	0	0	0	111.4	M363 L364 S369 V370 V371 V434 V437	M363-L367 PolarHBondContact O-N 3.02Å; L364-L367 WeakPolarHBondContact O-CB 3.39Å; L364-L367 PolarHBondContact O-N 3.46Å; L367-S369 PolarHBondContact O-N 3.14Å; L367-V370 PolarHBondContact O-N 3.41Å; L367-V370 VanDerWaalsContact O-N 3.15Å; L367-V371 HydrophobicContact CD2-CG2 3.9Å; L367-V371 VanDerWaalsContact O-CG2 3.29Å; L367-V371 WeakPolarHBondContact O-CG2 3.36Å; L367-V371 PolarHBondContact O-N 3.48Å; L367-V434 HydrophobicContact CB-CG1 4.03Å; L367-V437 HydrophobicContact CD1-CG1 3.86Å
368	L	90.9	Very high	89.5	Confident	20 Å²	20	21.7 Å²	21.7	11%	0.105	11%	0.112	C	C	.	.	H	α-helix	trans	-56.7	-38.3	176.5	-73.9	173.6	0	0	0	111.8	L235 T239 L242 L364 C365 V366 V370 V371 Y372	L235-L368 HydrophobicContact CD2-CD1 4.03Å; T239-L368 HydrophobicContact CG2-CD1 4.23Å; T239-L368 HydrophobicContact CG2-CD2 4.2Å; L242-L368 HydrophobicContact CD1-CD2 4.43Å; L364-L368 HydrophobicContact CD2-CD1 3.72Å; L364-L368 HydrophobicContact CD2-CG 4.14Å; L364-L368 WeakPolarHBondContact O-CG 3.28Å; L364-L368 PolarHBondContact O-N 3.01Å; C365-L368 PolarHBondContact O-N 3.06Å; V366-L368 PolarHBondContact O-N 3.46Å; L368-V370 PolarHBondContact O-N 2.95Å; L368-V371 PolarHBondContact O-N 2.97Å; L368-Y372 WeakPolarHBondContact O-CD1 3.2Å; L368-Y372 PolarHBondContact O-N 3.07Å
369	S	92.6	Very high	89.1	Confident	1 Å²	1	22.2 Å²	22.2	1%	0.007	12%	0.115	C	C	.	.	H	α-helix	trans	-64.4	-38.5	178.4	76.8	0	0	0	0	114.4	S330 C365 V366 L367 S373	S330-S369 WeakPolarHBondContact CB-O 3.37Å; S330-S369 PolarHBondContact O-OG 3.06Å; C365-S369 PolarHBondContact O-N 3.23Å; V366-S369 WeakPolarHBondContact O-CA 3.42Å; V366-S369 WeakPolarHBondContact O-CB 3.27Å; V366-S369 PolarHBondContact O-N 3.06Å; V366-S369 PolarHBondContact O-OG 3.3Å; L367-S369 PolarHBondContact O-N 3.14Å; S369-S373 VanDerWaalsContact O-CB 3.29Å; S369-S373 WeakPolarHBondContact O-CB 3.42Å; S369-S373 PolarHBondContact O-N 3.43Å; S369-S373 VanDerWaalsContact O-N 3.11Å; S369-S373 PolarHBondContact O-OG 3.35Å
370	V	92.5	Very high	88.6	Confident	0 Å²	0	20.7 Å²	20.7	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-66.7	-47.9	174.2	-178.6	0	0	0	0	110.1	V366 L367 L368 Y372 S373 L374 Y435 L439	V366-V370 WeakPolarHBondContact O-CG2 3.49Å; V366-V370 PolarHBondContact O-N 3.37Å; V366-V370 VanDerWaalsContact O-N 3.11Å; L367-V370 PolarHBondContact O-N 3.41Å; L367-V370 VanDerWaalsContact O-N 3.15Å; L368-V370 PolarHBondContact O-N 2.95Å; V370-Y372 PolarHBondContact O-N 3.08Å; V370-S373 WeakPolarHBondContact CA-OG 3.5Å; V370-S373 PolarHBondContact O-N 3.16Å; V370-S373 PolarHBondContact O-OG 3.42Å; V370-L374 HydrophobicContact CG1-CD1 4.36Å; V370-L374 WeakPolarHBondContact O-CB 3.5Å; V370-L374 PolarHBondContact O-N 3.06Å; V370-Y435 HydrophobicContact CG2-CD1 3.54Å; V370-Y435 HydrophobicContact CG2-CE1 4.06Å; V370-L439 HydrophobicContact CG1-CD2 3.89Å; V370-L439 HydrophobicContact CG1-CG 4.14Å
371	V	90.8	Very high	87.9	Confident	2 Å²	2	16.4 Å²	16.4	1%	0.012	8%	0.084	C	C	.	.	H	α-helix	trans	-59.4	-46.6	-177.3	177.2	0	0	0	0	111.2	L242 L367 L368 R375 G438 V441 F445	L242-V371 HydrophobicContact CD1-CG1 4.02Å; L242-V371 HydrophobicContact CD2-CB 4.38Å; L242-V371 HydrophobicContact CD2-CG1 3.62Å; L242-V371 HydrophobicContact CG-CG1 4.49Å; L367-V371 HydrophobicContact CD2-CG2 3.9Å; L367-V371 VanDerWaalsContact O-CG2 3.29Å; L367-V371 WeakPolarHBondContact O-CG2 3.36Å; L367-V371 PolarHBondContact O-N 3.48Å; L368-V371 PolarHBondContact O-N 2.97Å; V371-R375 PolarHBondContact O-N 3.21Å; V371-G438 WeakPolarHBondContact CG2-O 3.29Å; V371-V441 HydrophobicContact CG1-CG1 4.4Å; V371-V441 HydrophobicContact CG2-CB 4.01Å; V371-V441 HydrophobicContact CG2-CG1 3.76Å; V371-F445 HydrophobicContact CG1-CD2 3.76Å; V371-F445 HydrophobicContact CG1-CE2 4.18Å
372	Y	89.1	Confident	86.4	Confident	4 Å²	4	15.4 Å²	15.4	2%	0.016	8%	0.081	C	C	.	.	H	α-helix	trans	-71.9	-32.7	178.3	72.6	-123	0	0	0	112.8	S241 S254 S257 L368 V370 L374 R375 L376	S241-Y372 WeakPolarHBondContact OG-CB 3.35Å; S241-Y372 WeakPolarHBondContact OG-CD1 3.47Å; S254-Y372 VanDerWaalsContact CB-CE2 3.45Å; S257-Y372 PolarHBondContact OG-OH 3.02Å; L368-Y372 WeakPolarHBondContact O-CD1 3.2Å; L368-Y372 PolarHBondContact O-N 3.07Å; V370-Y372 PolarHBondContact O-N 3.08Å; Y372-L374 VanDerWaalsContact C-N 3.33Å; Y372-R375 PolarHBondContact O-N 3.39Å; Y372-L376 HydrophobicContact CD2-CD1 4.42Å; Y372-L376 WeakPolarHBondContact O-CG 2.88Å; Y372-L376 PolarHBondContact O-N 3.13Å
373	S	90.2	Very high	84.7	Confident	1 Å²	1	19 Å²	19	1%	0.007	12%	0.117	C	C	.	.	H	α-helix	trans	-66.5	-39.2	177.6	67.9	0	0	0	0	111.3	L326 S330 S369 V370 L376 F377	L326-S373 WeakPolarHBondContact O-CB 3.3Å; S330-S373 WeakPolarHBondContact CB-OG 3.46Å; S330-S373 PolarHBondContact OG-OG 3.28Å; S369-S373 VanDerWaalsContact O-CB 3.29Å; S369-S373 WeakPolarHBondContact O-CB 3.42Å; S369-S373 PolarHBondContact O-N 3.43Å; S369-S373 VanDerWaalsContact O-N 3.11Å; S369-S373 PolarHBondContact O-OG 3.35Å; V370-S373 WeakPolarHBondContact CA-OG 3.5Å; V370-S373 PolarHBondContact O-N 3.16Å; V370-S373 PolarHBondContact O-OG 3.42Å; S373-L376 PolarHBondContact O-N 3.29Å; S373-F377 WeakPolarHBondContact O-CB 3.36Å; S373-F377 PolarHBondContact O-N 3.49Å
374	L	87.9	Confident	83	Confident	3 Å²	3	19.2 Å²	19.2	2%	0.016	12%	0.124	C	C	.	.	H	α-helix	trans	-62	-48.4	171.1	-90.8	174.8	0	0	0	111.9	F327 V370 Y372 L376 F377 F378 L439 F443	F327-L374 HydrophobicContact CE1-CD2 3.95Å; F327-L374 HydrophobicContact CE1-CG 3.91Å; F327-L374 HydrophobicContact CZ-CD2 3.43Å; F327-L374 VanDerWaalsContact CZ-CD2 3.43Å; F327-L374 HydrophobicContact CZ-CG 3.84Å; V370-L374 HydrophobicContact CG1-CD1 4.36Å; V370-L374 WeakPolarHBondContact O-CB 3.5Å; V370-L374 PolarHBondContact O-N 3.06Å; Y372-L374 VanDerWaalsContact C-N 3.33Å; L374-L376 VanDerWaalsContact C-N 3.34Å; L374-L376 PolarHBondContact O-N 3.28Å; L374-F377 WeakPolarHBondContact O-CB 3.4Å; L374-F377 PolarHBondContact O-N 2.96Å; L374-F377 VanDerWaalsContact O-N 3.17Å; L374-F378 HydrophobicContact CD2-CE2 3.95Å; L374-F378 WeakPolarHBondContact O-CD2 3.36Å; L374-F378 PolarHBondContact O-N 3.34Å; L374-F378 VanDerWaalsContact O-N 3.08Å; L374-L439 VanDerWaalsContact CD1-CA 3.49Å; L374-L439 HydrophobicContact CD1-CB 4.24Å; L374-L439 HydrophobicContact CD1-CD2 3.51Å; L374-L439 HydrophobicContact CD1-CG 4.42Å; L374-L439 WeakPolarHBondContact CD1-O 3.32Å; L374-L439 HydrophobicContact CD2-CD2 3.96Å; L374-L439 HydrophobicContact CG-CD2 3.85Å; L374-F443 HydrophobicContact CD1-CD2 4.22Å; L374-F443 HydrophobicContact CD2-CD2 4.33Å; L374-F443 HydrophobicContact CD2-CE2 3.97Å; L374-F443 HydrophobicContact CD2-CZ 4.45Å
375	R	85.8	Confident	81	Confident	21 Å²	21	22.2 Å²	22.2	8%	0.079	15%	0.146	C	C	.	.	H	α-helix	trans	-52.1	-56.7	175.9	-178.8	-172.6	-177.8	-137.3	-0.9	109.5	S241 L242 C244 V371 Y372 F377 F378 L379	S241-R375 PolarHBondContact O-NH1 3.22Å; L242-R375 PolarHBondContact O-NE 2.94Å; L242-R375 VanDerWaalsContact O-NE 3.13Å; L242-R375 PolarHBondContact O-NH1 2.89Å; L242-R375 VanDerWaalsContact O-NH1 3.13Å; L242-R375 PolarHBondContact O-NH2 3.4Å; C244-R375 VanDerWaalsContact O-CZ 3.31Å; C244-R375 PolarHBondContact O-NH1 3.41Å; C244-R375 PolarHBondContact O-NH2 3.47Å; V371-R375 PolarHBondContact O-N 3.21Å; Y372-R375 PolarHBondContact O-N 3.39Å; R375-F377 VanDerWaalsContact C-N 3.28Å; R375-F377 PolarHBondContact O-N 3.13Å; R375-F378 PolarHBondContact O-N 3.48Å; R375-F378 VanDerWaalsContact O-N 3.13Å; R375-L379 HydrophobicContact CG-CD1 4.02Å; R375-L379 HydrophobicContact CG-CG 4.26Å; R375-L379 VanDerWaalsContact O-CG 3.28Å; R375-L379 WeakPolarHBondContact O-CG 3.25Å; R375-L379 PolarHBondContact O-N 2.68Å
376	L	84.4	Confident	79	Confident	3 Å²	3	24.6 Å²	24.6	2%	0.016	16%	0.162	C	C	.	.	H	α-helix	trans	-54.7	-43.3	179.4	-77.1	168.8	0	0	0	112.3	M247 M251 L326 Y372 S373 L374 F378 L379 F380	M247-L376 HydrophobicContact CE-CD2 4.37Å; M247-L376 HydrophobicContact SD-CD2 4.48Å; M251-L376 HydrophobicContact SD-CD1 3.68Å; M251-L376 HydrophobicContact SD-CD2 4.3Å; L326-L376 HydrophobicContact CD1-CB 4.45Å; L326-L376 HydrophobicContact CD2-CB 4.34Å; Y372-L376 HydrophobicContact CD2-CD1 4.42Å; Y372-L376 WeakPolarHBondContact O-CG 2.88Å; Y372-L376 PolarHBondContact O-N 3.13Å; S373-L376 PolarHBondContact O-N 3.29Å; L374-L376 VanDerWaalsContact C-N 3.34Å; L374-L376 PolarHBondContact O-N 3.28Å; L376-F378 PolarHBondContact O-N 2.89Å; L376-L379 PolarHBondContact O-N 3.31Å; L376-L379 VanDerWaalsContact O-N 3.13Å; L376-F380 WeakPolarHBondContact O-CD2 3.32Å; L376-F380 PolarHBondContact O-N 3.07Å
377	F	86.2	Confident	77.1	Confident	11 Å²	11	33.5 Å²	33.5	5%	0.048	20%	0.201	C	C	.	.	H	α-helix	trans	-55.9	-47.5	177.5	-179.7	-95.1	0	0	0	112.1	F312 F319 L322 F323 L326 F327 S373 L374 R375 F380	F312-F377 WeakPolarHBondContact CE1-O 3.29Å; F312-F377 HydrophobicContact CE2-CE1 4.25Å; F312-F377 AromaticContact CE2-CZ 3.95Å; F312-F377 HydrophobicContact CE2-CZ 3.95Å; F312-F377 HydrophobicContact CZ-CD1 4.37Å; F312-F377 AromaticContact CZ-CE1 3.82Å; F312-F377 HydrophobicContact CZ-CE1 3.82Å; F312-F377 HydrophobicContact CZ-CE2 4.38Å; F312-F377 AromaticContact CZ-CZ 3.81Å; F312-F377 HydrophobicContact CZ-CZ 3.81Å; F319-F377 AromaticContact CD2-CZ 3.86Å; F319-F377 HydrophobicContact CD2-CZ 3.86Å; F319-F377 HydrophobicContact CE2-CE1 4.11Å; F319-F377 AromaticContact CE2-CZ 3.46Å; F319-F377 HydrophobicContact CE2-CZ 3.46Å; F319-F377 VanDerWaalsContact CE2-CZ 3.46Å; F319-F377 AromaticContact CZ-CZ 3.87Å; F319-F377 HydrophobicContact CZ-CZ 3.87Å; L322-F377 HydrophobicContact CB-CD2 4.39Å; L322-F377 HydrophobicContact CB-CE2 4.17Å; F323-F377 HydrophobicContact CB-CE2 3.98Å; F323-F377 HydrophobicContact CD2-CE2 4.25Å; F323-F377 HydrophobicContact CD2-CZ 4.48Å; L326-F377 HydrophobicContact CD1-CB 3.89Å; L326-F377 HydrophobicContact CD1-CD2 4.14Å; F327-F377 HydrophobicContact CE2-CB 4.32Å; F327-F377 HydrophobicContact CE2-CD2 4.15Å; F327-F377 HydrophobicContact CE2-CG 4.12Å; S373-F377 WeakPolarHBondContact O-CB 3.36Å; S373-F377 PolarHBondContact O-N 3.49Å; L374-F377 WeakPolarHBondContact O-CB 3.4Å; L374-F377 PolarHBondContact O-N 2.96Å; L374-F377 VanDerWaalsContact O-N 3.17Å; R375-F377 VanDerWaalsContact C-N 3.28Å; R375-F377 PolarHBondContact O-N 3.13Å; F377-F380 PolarHBondContact O-N 3.38Å
378	F	81.8	Confident	75.1	Confident	42 Å²	42	32.5 Å²	32.5	18%	0.184	20%	0.197	C	C	.	.	H	α-helix	trans	-71.8	-27.7	177	-74	-71.2	0	0	0	113.9	L374 R375 L376 F380 D381 F443 V446	L374-F378 HydrophobicContact CD2-CE2 3.95Å; L374-F378 WeakPolarHBondContact O-CD2 3.36Å; L374-F378 PolarHBondContact O-N 3.34Å; L374-F378 VanDerWaalsContact O-N 3.08Å; R375-F378 PolarHBondContact O-N 3.48Å; R375-F378 VanDerWaalsContact O-N 3.13Å; L376-F378 PolarHBondContact O-N 2.89Å; F378-F380 VanDerWaalsContact C-N 3.26Å; F378-F380 PolarHBondContact O-N 3.35Å; F378-D381 WeakPolarHBondContact O-CB 3.45Å; F378-D381 PolarHBondContact O-N 3.42Å; F378-D381 VanDerWaalsContact O-N 3.09Å; F378-F443 HydrophobicContact CE1-CE1 4.44Å; F378-F443 HydrophobicContact CE2-CD1 4.08Å; F378-F443 AromaticContact CE2-CE1 3.8Å; F378-F443 HydrophobicContact CE2-CE1 3.8Å; F378-F443 HydrophobicContact CE2-CZ 4.16Å; F378-F443 AromaticContact CZ-CD1 3.97Å; F378-F443 HydrophobicContact CZ-CD1 3.97Å; F378-F443 AromaticContact CZ-CE1 3.34Å; F378-F443 HydrophobicContact CZ-CE1 3.34Å; F378-F443 AromaticContact CZ-CZ 3.84Å; F378-F443 HydrophobicContact CZ-CZ 3.84Å; F378-V446 HydrophobicContact CB-CG1 3.78Å; F378-V446 HydrophobicContact CB-CG2 4.21Å; F378-V446 HydrophobicContact CD1-CG1 4.15Å; F378-V446 HydrophobicContact CD2-CB 4.06Å; F378-V446 HydrophobicContact CD2-CG1 3.69Å; F378-V446 HydrophobicContact CD2-CG2 3.52Å; F378-V446 HydrophobicContact CE2-CG1 4.32Å; F378-V446 HydrophobicContact CE2-CG2 4.25Å; F378-V446 HydrophobicContact CG-CB 4.44Å; F378-V446 HydrophobicContact CG-CG1 3.6Å; F378-V446 HydrophobicContact CG-CG2 4.13Å
379	L	79	Confident	73.2	Confident	35 Å²	35	37.1 Å²	37.1	18%	0.183	22%	0.22	C	C	.	.	H	α-helix	trans	-69.9	-24.1	176.3	-65.5	-176.9	0	0	0	113	M247 V305 R375 L376 D381	M247-L379 HydrophobicContact CE-CB 4.19Å; M247-L379 HydrophobicContact SD-CB 4.1Å; M247-L379 HydrophobicContact SD-CD1 4.17Å; V305-L379 HydrophobicContact CB-CD1 4.44Å; V305-L379 HydrophobicContact CG1-CB 4.13Å; V305-L379 HydrophobicContact CG1-CD1 3.88Å; V305-L379 HydrophobicContact CG1-CD2 3.28Å; V305-L379 HydrophobicContact CG1-CG 3.89Å; V305-L379 HydrophobicContact CG2-CD1 3.58Å; V305-L379 HydrophobicContact CG2-CG 4.47Å; R375-L379 HydrophobicContact CG-CD1 4.02Å; R375-L379 HydrophobicContact CG-CG 4.26Å; R375-L379 VanDerWaalsContact O-CG 3.28Å; R375-L379 WeakPolarHBondContact O-CG 3.25Å; R375-L379 PolarHBondContact O-N 2.68Å; L376-L379 PolarHBondContact O-N 3.31Å; L376-L379 VanDerWaalsContact O-N 3.13Å; L379-D381 PolarHBondContact O-N 3.37Å
380	F	77.6	Confident	71	Confident	1 Å²	1	39.6 Å²	39.6	0%	0.004	24%	0.237	C	C	.	.	T	Hydrogen-bonded Turn	trans	-73.9	-9.7	170.6	-74.3	-70.1	0	0	0	113.3	M247 L291 V292 Y295 F312 L322 L326 L376 F377 F378 G382	M247-F380 HydrophobicContact CE-CD1 3.91Å; M247-F380 HydrophobicContact CE-CD2 4.21Å; M247-F380 HydrophobicContact CE-CE1 3.61Å; M247-F380 HydrophobicContact CE-CE2 3.9Å; M247-F380 HydrophobicContact CE-CG 4.22Å; M247-F380 HydrophobicContact CE-CZ 3.61Å; L291-F380 HydrophobicContact CD2-CD1 4.04Å; L291-F380 HydrophobicContact CD2-CE1 3.41Å; L291-F380 VanDerWaalsContact CD2-CE1 3.41Å; L291-F380 HydrophobicContact CD2-CE2 4.12Å; L291-F380 HydrophobicContact CD2-CZ 3.45Å; L291-F380 VanDerWaalsContact CD2-CZ 3.45Å; V292-F380 HydrophobicContact CG2-CE1 4.02Å; V292-F380 HydrophobicContact CG2-CZ 3.54Å; Y295-F380 AromaticContact CD1-CD1 3.53Å; Y295-F380 HydrophobicContact CD1-CD1 3.53Å; Y295-F380 HydrophobicContact CD1-CE1 4.22Å; Y295-F380 HydrophobicContact CD2-CD1 4.21Å; Y295-F380 HydrophobicContact CD2-CE1 4.28Å; Y295-F380 HydrophobicContact CE1-CB 4.12Å; Y295-F380 AromaticContact CE1-CD1 3.73Å; Y295-F380 HydrophobicContact CE1-CD1 3.73Å; Y295-F380 HydrophobicContact CE1-CG 4.37Å; Y295-F380 HydrophobicContact CE2-CD1 4.36Å; Y295-F380 AromaticContact CG-CD1 3.79Å; Y295-F380 HydrophobicContact CG-CD1 3.79Å; Y295-F380 HydrophobicContact CG-CE1 4Å; F312-F380 HydrophobicContact CD1-CB 4.1Å; F312-F380 HydrophobicContact CE1-CB 4.07Å; L322-F380 HydrophobicContact CD1-CB 4.22Å; L322-F380 HydrophobicContact CD2-CB 4.38Å; L322-F380 HydrophobicContact CD2-CD1 4.5Å; L322-F380 HydrophobicContact CD2-CD2 3.96Å; L322-F380 HydrophobicContact CD2-CE2 4.35Å; L322-F380 HydrophobicContact CD2-CG 4.04Å; L326-F380 HydrophobicContact CD1-CD2 3.76Å; L326-F380 HydrophobicContact CD1-CE2 3.81Å; L326-F380 HydrophobicContact CD2-CE2 4.18Å; L376-F380 WeakPolarHBondContact O-CD2 3.32Å; L376-F380 PolarHBondContact O-N 3.07Å; F377-F380 PolarHBondContact O-N 3.38Å; F378-F380 VanDerWaalsContact C-N 3.26Å; F378-F380 PolarHBondContact O-N 3.35Å; F380-G382 VanDerWaalsContact C-N 3.31Å; F380-G382 PolarHBondContact O-N 3.02Å
381	D	72.8	Confident	69.1	Low	19 Å²	19	39.6 Å²	39.6	10%	0.102	24%	0.238	C	C	.	.			trans	-94.3	64.9	172.9	-158.2	19.3	0	0	0	109.9	S311 F312 L313 F378 L379 G383	S311-D381 PolarHBondContact OG-OD1 2.98Å; F312-D381 HydrophobicContact CD1-CB 4.08Å; F312-D381 HydrophobicContact CE1-CB 3.39Å; F312-D381 HydrophobicContact CE2-CB 4.48Å; F312-D381 HydrophobicContact CZ-CB 3.62Å; L313-D381 WeakPolarHBondContact CD1-OD2 3.41Å; L313-D381 WeakPolarHBondContact CG-OD1 3.34Å; L313-D381 VanDerWaalsContact CG-OD2 3.26Å; L313-D381 WeakPolarHBondContact CG-OD2 3.3Å; F378-D381 WeakPolarHBondContact O-CB 3.45Å; F378-D381 PolarHBondContact O-N 3.42Å; F378-D381 VanDerWaalsContact O-N 3.09Å; L379-D381 PolarHBondContact O-N 3.37Å; D381-G383 PolarHBondContact O-N 2.95Å
382	G	60.6	Low	67.4	Low	14 Å²	14	45.3 Å²	45.3	14%	0.144	26%	0.259	C	S	.	.			trans	-71.5	114.5	171.2	0	0	0	0	0	107.4	V308 V310 S311 F380 G384	V308-G382 WeakPolarHBondContact O-CA 3.13Å; V310-G382 CarbonylContact C-O 3.3Å; V310-G382 VanDerWaalsContact C-O 3.3Å; V310-G382 PolarHBondContact O-N 3Å; S311-G382 PolarHBondContact N-O 3.49Å; F380-G382 VanDerWaalsContact C-N 3.31Å; F380-G382 PolarHBondContact O-N 3.02Å; G382-G384 PolarHBondContact O-N 2.93Å
383	G	55.8	Low	65.5	Low	75 Å²	75	55.1 Å²	55.1	77%	0.773	30%	0.296	S	S	*	.			trans	-60.3	27.7	-176.2	0	0	0	0	0	116.8	D381	D381-G383 PolarHBondContact O-N 2.95Å
384	G	55.4	Low	63.8	Low	22 Å²	22	57.7 Å²	57.7	23%	0.227	31%	0.307	C	S	.	.			trans	-82.6	153.4	171.3	0	0	0	0	0	113.4	G382	G382-G384 PolarHBondContact O-N 2.93Å
385	V	49.5	Very low	62.4	Low	147 Å²	147	58 Å²	58	89%	0.891	31%	0.308	S	S	*	.			trans	-88.9	-4.4	-169	-162.5	0	0	0	0	112.4	K387	V385-K387 PolarHBondContact O-N 2.89Å
386	S	51.7	Low	60.9	Low	55 Å²	55	60 Å²	60	39%	0.385	33%	0.325	S	S	.	.			trans	-81.6	108.9	-174	51.1	0	0	0	0	111.9	M309 V388	M309-S386 PolarHBondContact O-OG 3.1Å; S386-V388 PolarHBondContact O-N 3.25Å; S386-V388 VanDerWaalsContact O-N 3.14Å
387	K	51.7	Low	59.6	Low	188 Å²	188	65.5 Å²	65.5	82%	0.817	35%	0.354	S	S	*	.			trans	-65.6	104.8	160.8	-71	-179.2	-179.9	176.4	0	108.4	V385 I389	V385-K387 PolarHBondContact O-N 2.89Å; K387-I389 PolarHBondContact O-N 3.04Å
388	V	51.7	Low	58.5	Low	19 Å²	19	65.4 Å²	65.4	12%	0.115	35%	0.354	C	S	.	.			trans	-76.7	99.3	175	-179.4	0	0	0	0	108.5	V310 S386 S390 I391	V310-V388 HydrophobicContact CB-CG2 4.45Å; V310-V388 HydrophobicContact CG1-CG2 4.22Å; V310-V388 HydrophobicContact CG2-CB 4.48Å; V310-V388 HydrophobicContact CG2-CG2 3.53Å; S386-V388 PolarHBondContact O-N 3.25Å; S386-V388 VanDerWaalsContact O-N 3.14Å; V388-S390 WeakPolarHBondContact CG1-OG 3.37Å; V388-S390 PolarHBondContact O-N 3.31Å; V388-I391 HydrophobicContact CB-CD1 3.7Å; V388-I391 HydrophobicContact CB-CG1 3.96Å; V388-I391 HydrophobicContact CG1-CD1 4.14Å; V388-I391 HydrophobicContact CG1-CG1 3.85Å; V388-I391 WeakPolarHBondContact O-CB 3.09Å; V388-I391 WeakPolarHBondContact O-CG1 3.25Å; V388-I391 PolarHBondContact O-N 2.68Å
389	I	49.2	Very low	57.6	Low	117 Å²	117	65.7 Å²	65.7	60%	0.6	36%	0.357	S	S	*	.	G	3₁₀ helix	trans	-61.1	-28.2	-176.6	-68.6	171	0	0	0	112.1	K387 I391 R392	K387-I389 PolarHBondContact O-N 3.04Å; I389-I391 VanDerWaalsContact C-N 3.33Å; I389-I391 PolarHBondContact O-N 3.36Å; I389-R392 PolarHBondContact O-N 2.93Å; I389-R392 PolarHBondContact O-NE 3.02Å
390	S	46.5	Very low	57	Low	52 Å²	52	71.7 Å²	71.7	36%	0.364	38%	0.379	S	S	.	.	G	3₁₀ helix	trans	-72.4	-19.3	-176.5	51.6	0	0	0	0	114.5	H67 V388 R392	H67-S390 PolarHBondContact NE2-O 3.34Å; V388-S390 WeakPolarHBondContact CG1-OG 3.37Å; V388-S390 PolarHBondContact O-N 3.31Å; S390-R392 PolarHBondContact O-N 3.35Å
391	I	53.6	Low	56.5	Low	1 Å²	1	73.4 Å²	73.4	1%	0.005	39%	0.387	C	S	.	.	G	3₁₀ helix	trans	-55.3	-25.6	172.8	-65.6	176	0	0	0	110.5	Y295 V310 E318 V388 I389 R393 Y395	Y295-I391 HydrophobicContact CE2-CD1 4.31Å; V310-I391 HydrophobicContact CG1-CD1 3.86Å; E318-I391 HydrophobicContact CG-CG2 4.44Å; V388-I391 HydrophobicContact CB-CD1 3.7Å; V388-I391 HydrophobicContact CB-CG1 3.96Å; V388-I391 HydrophobicContact CG1-CD1 4.14Å; V388-I391 HydrophobicContact CG1-CG1 3.85Å; V388-I391 WeakPolarHBondContact O-CB 3.09Å; V388-I391 WeakPolarHBondContact O-CG1 3.25Å; V388-I391 PolarHBondContact O-N 2.68Å; I389-I391 VanDerWaalsContact C-N 3.33Å; I389-I391 PolarHBondContact O-N 3.36Å; I391-R393 PolarHBondContact O-N 3.1Å; I391-Y395 HydrophobicContact CB-CE2 4.16Å; I391-Y395 HydrophobicContact CG2-CD1 4.04Å; I391-Y395 HydrophobicContact CG2-CD2 3.8Å; I391-Y395 HydrophobicContact CG2-CE1 3.7Å; I391-Y395 HydrophobicContact CG2-CE2 3.41Å; I391-Y395 VanDerWaalsContact CG2-CE2 3.41Å; I391-Y395 HydrophobicContact CG2-CG 4.07Å; I391-Y395 WeakPolarHBondContact O-CD2 3.34Å; I391-Y395 VanDerWaalsContact O-CE2 3.28Å; I391-Y395 WeakPolarHBondContact O-CE2 3.33Å
392	R	53.8	Low	56.2	Low	121 Å²	121	72.8 Å²	72.8	46%	0.457	38%	0.384	S	S	.	.	G	3₁₀ helix	trans	-80.7	-15.4	-156.3	-62.9	-173.5	-73.4	-167.6	4.8	117	I389 S390	I389-R392 PolarHBondContact O-N 2.93Å; I389-R392 PolarHBondContact O-NE 3.02Å; S390-R392 PolarHBondContact O-N 3.35Å
393	R	49.6	Very low	56.5	Low	211 Å²	211	76.7 Å²	76.7	80%	0.796	40%	0.401	S	S	*	.	T	Hydrogen-bonded Turn	trans	-89	-50.1	-173.8	-78.2	-166.3	-108.3	-180	-1.9	113.7	I391 Y395 S396	I391-R393 PolarHBondContact O-N 3.1Å; R393-Y395 VanDerWaalsContact C-N 3.29Å; R393-Y395 PolarHBondContact O-N 3.14Å; R393-S396 PolarHBondContact O-OG 3.18Å
394	F	54.8	Low	57	Low	54 Å²	54	77.7 Å²	77.7	24%	0.237	39%	0.389	C	S	.	.	T	Hydrogen-bonded Turn	trans	-68.4	-29.1	-179	-88.4	-88.5	0	0	0	113.5	C63 H67 S396 I397 S398	C63-F394 HydrophobicContact CB-CE1 3.6Å; C63-F394 HydrophobicContact CB-CZ 3.88Å; C63-F394 VanDerWaalsContact O-CZ 3.29Å; C63-F394 WeakPolarHBondContact O-CZ 3.14Å; H67-F394 HydrophobicContact CB-CD2 4.02Å; H67-F394 HydrophobicContact CB-CE2 3.44Å; H67-F394 VanDerWaalsContact CB-CE2 3.44Å; H67-F394 HydrophobicContact CB-CZ 4.11Å; H67-F394 AromaticContact CD2-CD2 3.96Å; H67-F394 AromaticContact CD2-CE2 3.93Å; H67-F394 AromaticContact CG-CD2 3.82Å; H67-F394 AromaticContact CG-CE2 3.71Å; F394-S396 PolarHBondContact O-N 3.43Å; F394-I397 PolarHBondContact O-N 3.09Å; F394-S398 PolarHBondContact O-N 3.33Å; F394-S398 PolarHBondContact O-OG 3.4Å
395	Y	58.1	Low	57.5	Low	9 Å²	9	76.7 Å²	76.7	4%	0.035	38%	0.378	C	S	.	.	H	α-helix	trans	-67.4	-20.6	-175.5	-77.2	-118.8	0	0	0	113.8	L291 D294 Y295 Y321 I391 R393 S398 L399	L291-Y395 HydrophobicContact CD1-CE1 3.62Å; L291-Y395 WeakPolarHBondContact CD1-OH 3.23Å; L291-Y395 HydrophobicContact CG-CE1 4.39Å; L291-Y395 VanDerWaalsContact CG-OH 3.29Å; L291-Y395 WeakPolarHBondContact CG-OH 3.47Å; D294-Y395 WeakPolarHBondContact OD2-CE2 3.37Å; Y295-Y395 WeakPolarHBondContact CE2-OH 3.36Å; Y321-Y395 AromaticContact CD1-CD1 3.29Å; Y321-Y395 HydrophobicContact CD1-CD1 3.29Å; Y321-Y395 AromaticContact CD1-CE1 3.37Å; Y321-Y395 HydrophobicContact CD1-CE1 3.37Å; Y321-Y395 HydrophobicContact CD1-CG 4.45Å; Y321-Y395 AromaticContact CE1-CD1 3.34Å; Y321-Y395 HydrophobicContact CE1-CD1 3.34Å; Y321-Y395 AromaticContact CE1-CE1 3.36Å; Y321-Y395 HydrophobicContact CE1-CE1 3.36Å; Y321-Y395 HydrophobicContact CE1-CG 4.22Å; Y321-Y395 HydrophobicContact CG-CD1 4.11Å; I391-Y395 HydrophobicContact CB-CE2 4.16Å; I391-Y395 HydrophobicContact CG2-CD1 4.04Å; I391-Y395 HydrophobicContact CG2-CD2 3.8Å; I391-Y395 HydrophobicContact CG2-CE1 3.7Å; I391-Y395 HydrophobicContact CG2-CE2 3.41Å; I391-Y395 VanDerWaalsContact CG2-CE2 3.41Å; I391-Y395 HydrophobicContact CG2-CG 4.07Å; I391-Y395 WeakPolarHBondContact O-CD2 3.34Å; I391-Y395 VanDerWaalsContact O-CE2 3.28Å; I391-Y395 WeakPolarHBondContact O-CE2 3.33Å; R393-Y395 VanDerWaalsContact C-N 3.29Å; R393-Y395 PolarHBondContact O-N 3.14Å; Y395-S398 VanDerWaalsContact CA-OG 3.31Å; Y395-S398 WeakPolarHBondContact CA-OG 3.38Å; Y395-S398 PolarHBondContact O-OG 3.13Å; Y395-L399 PolarHBondContact O-N 3.41Å
396	S	54.7	Low	58.3	Low	63 Å²	63	70.7 Å²	70.7	44%	0.441	34%	0.343	S	S	.	.	H	α-helix	trans	-68.4	-37.8	-179.5	60.4	0	0	0	0	112.6	R393 F394 Y400	R393-S396 PolarHBondContact O-OG 3.18Å; F394-S396 PolarHBondContact O-N 3.43Å; S396-Y400 WeakPolarHBondContact O-CE2 3.27Å
397	I	58.4	Low	59.1	Low	120 Å²	120	72.6 Å²	72.6	62%	0.615	35%	0.352	S	S	*	.	H	α-helix	trans	-86.3	-36.1	-179.5	-63	166.2	0	0	0	110.2	F394 L399	F394-I397 PolarHBondContact O-N 3.09Å; I397-L399 VanDerWaalsContact C-N 3.32Å; I397-L399 PolarHBondContact O-N 3.29Å
398	S	62.3	Low	59.8	Low	8 Å²	8	66 Å²	66	6%	0.056	33%	0.325	C	S	.	.	H	α-helix	trans	-72.9	-19.8	-174.1	64.9	0	0	0	0	114.5	Y321 F394 Y395 Y400 L401 P402	Y321-S398 WeakPolarHBondContact CE2-OG 3.33Å; Y321-S398 WeakPolarHBondContact OH-CB 3.48Å; Y321-S398 PolarHBondContact OH-OG 3.44Å; F394-S398 PolarHBondContact O-N 3.33Å; F394-S398 PolarHBondContact O-OG 3.4Å; Y395-S398 VanDerWaalsContact CA-OG 3.31Å; Y395-S398 WeakPolarHBondContact CA-OG 3.38Å; Y395-S398 PolarHBondContact O-OG 3.13Å; S398-Y400 VanDerWaalsContact C-N 3.27Å; S398-Y400 PolarHBondContact O-N 3.17Å; S398-L401 PolarHBondContact O-N 2.99Å; S398-P402 WeakPolarHBondContact O-CD 3.19Å
399	L	62.8	Low	60.5	Low	48 Å²	48	65 Å²	65	25%	0.251	32%	0.32	S	S	.	.	T	Hydrogen-bonded Turn	trans	-65.4	-30	-179.9	-163.8	123.8	0	0	0	113.2	R317 Y321 Y395 I397	R317-L399 HydrophobicContact CG-CD1 4.38Å; Y321-L399 HydrophobicContact CD2-CB 4.17Å; Y321-L399 HydrophobicContact CD2-CD1 3.87Å; Y321-L399 HydrophobicContact CD2-CG 4.16Å; Y321-L399 HydrophobicContact CE2-CB 4.49Å; Y321-L399 HydrophobicContact CG-CD1 4.28Å; Y395-L399 PolarHBondContact O-N 3.41Å; I397-L399 VanDerWaalsContact C-N 3.32Å; I397-L399 PolarHBondContact O-N 3.29Å
400	Y	66.2	Low	61.4	Low	162 Å²	162	65.8 Å²	65.8	64%	0.635	32%	0.316	S	S	*	.	H	α-helix	trans	-78.7	-22.4	-179.3	-62.2	-72.9	0	0	0	113.1	S396 S398 L403 L404	S396-Y400 WeakPolarHBondContact O-CE2 3.27Å; S398-Y400 VanDerWaalsContact C-N 3.27Å; S398-Y400 PolarHBondContact O-N 3.17Å; Y400-L403 PolarHBondContact O-N 3.42Å; Y400-L404 WeakPolarHBondContact O-CB 3.37Å; Y400-L404 PolarHBondContact O-N 2.95Å
401	L	67.1	Low	62.5	Low	36 Å²	36	66 Å²	66	19%	0.188	32%	0.317	C	S	.	.	H	α-helix	trans	-70.4	-42	-175	-74	169.8	0	0	0	113.9	L60 L287 S398 L403 L404 S405	L60-L401 HydrophobicContact CD1-CD1 3.62Å; L60-L401 HydrophobicContact CD2-CD1 3.89Å; L60-L401 HydrophobicContact CG-CD1 4.35Å; L287-L401 HydrophobicContact CD1-CB 3.84Å; L287-L401 HydrophobicContact CD1-CD1 4.42Å; L287-L401 HydrophobicContact CD2-CD1 4.18Å; S398-L401 PolarHBondContact O-N 2.99Å; L401-L403 VanDerWaalsContact C-N 3.3Å; L401-L403 PolarHBondContact O-N 3.13Å; L401-L404 PolarHBondContact O-N 3.02Å; L401-S405 PolarHBondContact O-N 3.05Å
402	P	66.7	Low	63	Low	6 Å²	6	69.4 Å²	69.4	4%	0.039	33%	0.331	C	S	.	.	H	α-helix	trans	-60.1	-40.7	171.6	-26	34.8	0	0	0	111.9	L287 L325 S398 S405 S406	L287-P402 HydrophobicContact CD1-CG 3.85Å; L325-P402 HydrophobicContact CD2-CB 4.48Å; L325-P402 HydrophobicContact CD2-CG 3.56Å; L325-P402 HydrophobicContact CG-CG 4.4Å; S398-P402 WeakPolarHBondContact O-CD 3.19Å; P402-S405 WeakPolarHBondContact CA-OG 3.5Å; P402-S405 PolarHBondContact O-N 3.08Å; P402-S405 PolarHBondContact O-OG 3.47Å; P402-S406 PolarHBondContact O-N 3.18Å
403	L	66.3	Low	63.4	Low	96 Å²	96	64.1 Å²	64.1	50%	0.503	31%	0.311	S	S	.	.	H	α-helix	trans	-62.7	-46.5	175.3	-68.6	172.5	0	0	0	110.7	Y400 L401 S405 S406 V407	Y400-L403 PolarHBondContact O-N 3.42Å; L401-L403 VanDerWaalsContact C-N 3.3Å; L401-L403 PolarHBondContact O-N 3.13Å; L403-S405 VanDerWaalsContact C-N 3.31Å; L403-S405 PolarHBondContact O-N 3.03Å; L403-S406 PolarHBondContact O-N 2.98Å; L403-S406 VanDerWaalsContact O-N 3.13Å; L403-S406 PolarHBondContact O-OG 3.33Å; L403-V407 WeakPolarHBondContact O-CG2 3.23Å; L403-V407 PolarHBondContact O-N 3.16Å
404	L	66.9	Low	64	Low	96 Å²	96	61.3 Å²	61.3	50%	0.503	31%	0.305	S	S	.	.	H	α-helix	trans	-59.2	-41.9	174.7	-165.9	118.2	0	0	0	111.6	Y400 L401 S406 V407 L408	Y400-L404 WeakPolarHBondContact O-CB 3.37Å; Y400-L404 PolarHBondContact O-N 2.95Å; L401-L404 PolarHBondContact O-N 3.02Å; L404-S406 VanDerWaalsContact C-N 3.31Å; L404-S406 PolarHBondContact O-N 3.13Å; L404-V407 PolarHBondContact O-N 2.98Å; L404-L408 HydrophobicContact CD2-CD1 3.69Å; L404-L408 HydrophobicContact CD2-CG 4.29Å; L404-L408 HydrophobicContact CG-CD1 4.42Å; L404-L408 WeakPolarHBondContact O-CB 3.21Å; L404-L408 VanDerWaalsContact O-CG 3.3Å; L404-L408 WeakPolarHBondContact O-CG 3.47Å; L404-L408 PolarHBondContact O-N 2.93Å
405	S	66.1	Low	64.5	Low	2 Å²	2	62.5 Å²	62.5	1%	0.014	32%	0.32	C	S	.	.	H	α-helix	trans	-65.2	-32.4	176.6	71.8	0	0	0	0	113.4	C336 L401 P402 L403 G409	C336-S405 PolarHBondContact SG-OG 3.31Å; L401-S405 PolarHBondContact O-N 3.05Å; P402-S405 WeakPolarHBondContact CA-OG 3.5Å; P402-S405 PolarHBondContact O-N 3.08Å; P402-S405 PolarHBondContact O-OG 3.47Å; L403-S405 VanDerWaalsContact C-N 3.31Å; L403-S405 PolarHBondContact O-N 3.03Å; S405-G409 PolarHBondContact O-N 3.17Å
406	S	65.4	Low	64.4	Low	21 Å²	21	65.4 Å²	65.4	15%	0.147	34%	0.336	C	S	.	.	H	α-helix	trans	-70.3	-39	174.6	73.5	0	0	0	0	111.6	P402 L403 L404 G409 Y410	P402-S406 PolarHBondContact O-N 3.18Å; L403-S406 PolarHBondContact O-N 2.98Å; L403-S406 VanDerWaalsContact O-N 3.13Å; L403-S406 PolarHBondContact O-OG 3.33Å; L404-S406 VanDerWaalsContact C-N 3.31Å; L404-S406 PolarHBondContact O-N 3.13Å; S406-G409 PolarHBondContact O-N 2.96Å; S406-Y410 WeakPolarHBondContact O-CB 3.13Å; S406-Y410 PolarHBondContact O-N 3.44Å
407	V	69.1	Low	64.3	Low	95 Å²	95	64.2 Å²	64.2	58%	0.576	33%	0.326	S	S	*	.	H	α-helix	trans	-67.2	-45.4	175.3	174.4	0	0	0	0	110.4	L403 L404 Y410 S411	L403-V407 WeakPolarHBondContact O-CG2 3.23Å; L403-V407 PolarHBondContact O-N 3.16Å; L404-V407 PolarHBondContact O-N 2.98Å; V407-Y410 PolarHBondContact O-N 3.41Å; V407-S411 WeakPolarHBondContact O-CB 3.04Å; V407-S411 PolarHBondContact O-N 3.29Å; V407-S411 PolarHBondContact O-OG 3.4Å
408	L	66.1	Low	63.8	Low	48 Å²	48	65.3 Å²	65.3	25%	0.251	34%	0.338	S	S	.	.	H	α-helix	trans	-60.5	-47.4	174.9	-71.2	176.5	0	0	0	110.9	L404 Y410 S411 Y412	L404-L408 HydrophobicContact CD2-CD1 3.69Å; L404-L408 HydrophobicContact CD2-CG 4.29Å; L404-L408 HydrophobicContact CG-CD1 4.42Å; L404-L408 WeakPolarHBondContact O-CB 3.21Å; L404-L408 VanDerWaalsContact O-CG 3.3Å; L404-L408 WeakPolarHBondContact O-CG 3.47Å; L404-L408 PolarHBondContact O-N 2.93Å; L408-Y410 VanDerWaalsContact C-N 3.3Å; L408-Y410 PolarHBondContact O-N 2.74Å; L408-S411 WeakPolarHBondContact CA-OG 3.34Å; L408-S411 PolarHBondContact O-N 3.39Å; L408-S411 PolarHBondContact O-OG 3.44Å; L408-Y412 HydrophobicContact CB-CD2 4.28Å; L408-Y412 HydrophobicContact CB-CE2 4.34Å; L408-Y412 HydrophobicContact CD2-CE2 4.35Å; L408-Y412 WeakPolarHBondContact O-CB 3.28Å; L408-Y412 WeakPolarHBondContact O-CD2 3.2Å; L408-Y412 PolarHBondContact O-N 3.27Å
409	G	65.8	Low	63.2	Low	0 Å²	0	67.5 Å²	67.5	0%	0	36%	0.361	C	S	.	.	H	α-helix	trans	-57.2	-44.4	176.8	0	0	0	0	0	112.1	S405 S406 L413	S405-G409 PolarHBondContact O-N 3.17Å; S406-G409 PolarHBondContact O-N 2.96Å; G409-L413 WeakPolarHBondContact O-CB 3.25Å; G409-L413 WeakPolarHBondContact O-CG 3.24Å; G409-L413 PolarHBondContact O-N 3.37Å
410	Y	69.1	Low	62.5	Low	133 Å²	133	73.6 Å²	73.6	52%	0.522	38%	0.382	S	S	.	.	H	α-helix	trans	-65.1	-45	175.7	-175.1	-104.5	0	0	0	112.6	F339 S406 V407 L408 L413 F414	F339-Y410 HydrophobicContact CD1-CD2 4.2Å; F339-Y410 AromaticContact CE1-CD2 3.57Å; F339-Y410 HydrophobicContact CE1-CD2 3.57Å; F339-Y410 HydrophobicContact CE1-CE2 4.37Å; F339-Y410 HydrophobicContact CE1-CG 4.46Å; F339-Y410 AromaticContact CZ-CD2 3.81Å; F339-Y410 HydrophobicContact CZ-CD2 3.81Å; F339-Y410 HydrophobicContact CZ-CG 4.33Å; S406-Y410 WeakPolarHBondContact O-CB 3.13Å; S406-Y410 PolarHBondContact O-N 3.44Å; V407-Y410 PolarHBondContact O-N 3.41Å; L408-Y410 VanDerWaalsContact C-N 3.3Å; L408-Y410 PolarHBondContact O-N 2.74Å; Y410-L413 PolarHBondContact O-N 3.45Å; Y410-F414 WeakPolarHBondContact O-CB 3.4Å; Y410-F414 PolarHBondContact O-N 3.48Å
411	S	68.8	Low	61.9	Low	56 Å²	56	68.7 Å²	68.7	39%	0.392	37%	0.369	S	S	.	.	H	α-helix	trans	-66	-40.4	180	60.9	0	0	0	0	112.5	V407 L408 F414 S415	V407-S411 WeakPolarHBondContact O-CB 3.04Å; V407-S411 PolarHBondContact O-N 3.29Å; V407-S411 PolarHBondContact O-OG 3.4Å; L408-S411 WeakPolarHBondContact CA-OG 3.34Å; L408-S411 PolarHBondContact O-N 3.39Å; L408-S411 PolarHBondContact O-OG 3.44Å; S411-F414 PolarHBondContact O-N 3.15Å; S411-S415 PolarHBondContact O-N 3.23Å; S411-S415 VanDerWaalsContact O-N 3.12Å
412	Y	64.5	Low	61.5	Low	73 Å²	73	73.1 Å²	73.1	29%	0.286	39%	0.393	S	S	.	.	H	α-helix	trans	-65.4	-44.1	176	-82.4	-67.1	0	0	0	110.9	V276 L408 F414 S415 L416	V276-Y412 HydrophobicContact CG2-CD1 4.48Å; V276-Y412 HydrophobicContact CG2-CG 4.06Å; L408-Y412 HydrophobicContact CB-CD2 4.28Å; L408-Y412 HydrophobicContact CB-CE2 4.34Å; L408-Y412 HydrophobicContact CD2-CE2 4.35Å; L408-Y412 WeakPolarHBondContact O-CB 3.28Å; L408-Y412 WeakPolarHBondContact O-CD2 3.2Å; L408-Y412 PolarHBondContact O-N 3.27Å; Y412-F414 VanDerWaalsContact C-N 3.35Å; Y412-F414 PolarHBondContact O-N 3.48Å; Y412-S415 PolarHBondContact O-N 2.77Å; Y412-S415 PolarHBondContact O-OG 3.13Å; Y412-L416 WeakPolarHBondContact O-CB 3.42Å; Y412-L416 WeakPolarHBondContact O-CG 3.35Å; Y412-L416 PolarHBondContact O-N 2.85Å
413	L	62.4	Low	61	Low	9 Å²	9	77.1 Å²	77.1	5%	0.047	41%	0.414	C	S	.	.	H	α-helix	trans	-60.6	-43.6	174.2	-80.2	-163	0	0	0	112.9	L273 F339 A343 G409 Y410 S415 L416 V417	L273-L413 HydrophobicContact CD2-CD2 3.56Å; F339-L413 HydrophobicContact CB-CD1 3.37Å; F339-L413 HydrophobicContact CB-CG 4.02Å; F339-L413 HydrophobicContact CD1-CD1 3.85Å; F339-L413 HydrophobicContact CG-CD1 3.99Å; F339-L413 WeakPolarHBondContact O-CD1 3.49Å; A343-L413 HydrophobicContact CB-CD1 4.22Å; A343-L413 HydrophobicContact CB-CD2 3.76Å; G409-L413 WeakPolarHBondContact O-CB 3.25Å; G409-L413 WeakPolarHBondContact O-CG 3.24Å; G409-L413 PolarHBondContact O-N 3.37Å; Y410-L413 PolarHBondContact O-N 3.45Å; L413-S415 PolarHBondContact O-N 3.12Å; L413-L416 PolarHBondContact O-N 3.23Å; L413-L416 VanDerWaalsContact O-N 3.16Å; L413-V417 PolarHBondContact O-N 3.24Å
414	F	63	Low	60.6	Low	153 Å²	153	81 Å²	81	67%	0.671	43%	0.427	S	S	*	.	H	α-helix	trans	-60.1	-33.4	179.4	-171.2	-98.4	0	0	0	111.5	Y410 S411 Y412	Y410-F414 WeakPolarHBondContact O-CB 3.4Å; Y410-F414 PolarHBondContact O-N 3.48Å; S411-F414 PolarHBondContact O-N 3.15Å; Y412-F414 VanDerWaalsContact C-N 3.35Å; Y412-F414 PolarHBondContact O-N 3.48Å
415	S	63.9	Low	60.6	Low	78 Å²	78	78.7 Å²	78.7	55%	0.545	42%	0.418	S	S	.	.	H	α-helix	trans	-76.9	-34.1	175.8	70.3	0	0	0	0	114.3	S411 Y412 L413	S411-S415 PolarHBondContact O-N 3.23Å; S411-S415 VanDerWaalsContact O-N 3.12Å; Y412-S415 PolarHBondContact O-N 2.77Å; Y412-S415 PolarHBondContact O-OG 3.13Å; L413-S415 PolarHBondContact O-N 3.12Å
416	L	56.1	Low	60.8	Low	71 Å²	71	88.8 Å²	88.8	37%	0.372	46%	0.458	S	S	.	.	H	α-helix	trans	-92.3	-28.2	-171	-72.2	165.2	0	0	0	113.2	D272 V276 Y412 L413	D272-L416 HydrophobicContact CB-CD1 3.72Å; D272-L416 HydrophobicContact CB-CD2 3.82Å; D272-L416 HydrophobicContact CB-CG 4.38Å; V276-L416 HydrophobicContact CG2-CD1 4.22Å; Y412-L416 WeakPolarHBondContact O-CB 3.42Å; Y412-L416 WeakPolarHBondContact O-CG 3.35Å; Y412-L416 PolarHBondContact O-N 2.85Å; L413-L416 PolarHBondContact O-N 3.23Å; L413-L416 VanDerWaalsContact O-N 3.16Å
417	V	54.3	Low	61.1	Low	38 Å²	38	90.1 Å²	90.1	23%	0.23	46%	0.462	C	S	.	.			trans	-129.3	77.6	-169.3	-169.6	0	0	0	0	110.1	L413 G419	L413-V417 PolarHBondContact O-N 3.24Å; V417-G419 PolarHBondContact O-N 2.7Å; V417-G419 VanDerWaalsContact O-N 3.08Å
418	V	47.2	Very low	61.3	Low	142 Å²	142	86 Å²	86	86%	0.861	44%	0.437	S	S	*	.	S	Bend	trans	-69.8	4.4	178.2	175.4	0	0	0	0	113.2
419	G	49.9	Very low	61.9	Low	54 Å²	54	88.6 Å²	88.6	56%	0.557	45%	0.449	S	S	*	.	S	Bend	trans	-136.4	-9.8	-163.7	0	0	0	0	0	120.8	V417	V417-G419 PolarHBondContact O-N 2.7Å; V417-G419 VanDerWaalsContact O-N 3.08Å
420	Y	48.5	Very low	62.6	Low	177 Å²	177	93.1 Å²	93.1	69%	0.694	47%	0.472	S	S	*	.	S	Bend	trans	-141.2	0.1	-164.7	-66.3	-71.6	0	0	0	117.9	D422	Y420-D422 PolarHBondContact O-N 3.3Å
421	T	53.5	Low	63.4	Low	59 Å²	59	86.9 Å²	86.9	36%	0.362	45%	0.448	S	S	.	.			trans	-102.9	55.2	-179.5	60.9	0	0	0	0	112.3	L423	T421-L423 PolarHBondContact O-N 3.5Å
422	D	56.9	Low	64	Low	128 Å²	128	86.6 Å²	86.6	68%	0.684	45%	0.446	S	S	*	.			trans	-68.8	118	158.1	-75.3	-21	0	0	0	107.3	Y420 F424 C425	Y420-D422 PolarHBondContact O-N 3.3Å; D422-F424 PolarHBondContact O-N 3.31Å; D422-C425 PolarHBondContact O-N 3.45Å
423	L	57	Low	65.1	Low	90 Å²	90	87.2 Å²	87.2	47%	0.471	46%	0.458	S	S	.	.	T	Hydrogen-bonded Turn	trans	-55.6	-12.6	178	-73.2	167.4	0	0	0	113	F334 T421 S428	F334-L423 HydrophobicContact CE1-CD1 4.14Å; F334-L423 HydrophobicContact CE1-CD2 3.76Å; F334-L423 HydrophobicContact CZ-CD1 4.49Å; F334-L423 HydrophobicContact CZ-CD2 4.16Å; T421-L423 PolarHBondContact O-N 3.5Å; L423-S428 WeakPolarHBondContact O-CB 3.18Å; L423-S428 PolarHBondContact O-OG 3.5Å
424	F	57.9	Low	66.4	Low	178 Å²	178	87.9 Å²	87.9	78%	0.781	46%	0.462	S	S	*	.	T	Hydrogen-bonded Turn	trans	-105.8	8.7	-179.5	-64.1	-76	0	0	0	115.1	D422	D422-F424 PolarHBondContact O-N 3.31Å
425	C	67.4	Low	67.7	Low	47 Å²	47	80.8 Å²	80.8	32%	0.318	43%	0.43	S	S	.	.	S	Bend	trans	-64.7	148.9	176	-170	0	0	0	0	111.9	D422 Q427 S428 M429	D422-C425 PolarHBondContact O-N 3.45Å; C425-Q427 PolarHBondContact O-N 3.24Å; C425-S428 PolarHBondContact N-OG 2.87Å; C425-S428 WeakPolarHBondContact O-CB 3.25Å; C425-S428 PolarHBondContact O-N 3.23Å; C425-S428 PolarHBondContact O-OG 2.99Å; C425-M429 PolarHBondContact O-N 2.9Å
426	Y	70.5	Confident	68.9	Low	215 Å²	215	82 Å²	82	84%	0.843	43%	0.429	S	S	*	.	H	α-helix	trans	-51.9	-32.7	177.9	-73.7	-75.3	0	0	0	113.6	M429 L430	Y426-M429 PolarHBondContact O-N 2.83Å; Y426-L430 WeakPolarHBondContact O-CB 3.36Å; Y426-L430 PolarHBondContact O-N 3.48Å
427	Q	71.7	Confident	70.5	Confident	49 Å²	49	82 Å²	82	23%	0.229	43%	0.431	C	S	.	.	H	α-helix	trans	-69.4	-36.5	177.4	-66.7	168.9	-18.3	0	0	112.4	S346 G349 C425 M429 L430 L431	S346-Q427 VanDerWaalsContact CB-OE1 3.31Å; S346-Q427 PolarHBondContact O-NE2 3.04Å; S346-Q427 PolarHBondContact O-OE1 3.42Å; S346-Q427 PolarHBondContact OG-OE1 3.49Å; G349-Q427 VanDerWaalsContact CA-NE2 3.3Å; C425-Q427 PolarHBondContact O-N 3.24Å; Q427-M429 VanDerWaalsContact C-N 3.34Å; Q427-L430 PolarHBondContact O-N 3.05Å; Q427-L431 WeakPolarHBondContact O-CB 3.4Å; Q427-L431 PolarHBondContact O-N 3.42Å
428	S	73.8	Confident	72.1	Confident	8 Å²	8	80.1 Å²	80.1	6%	0.056	42%	0.42	C	S	.	.	H	α-helix	trans	-67.4	-39	175.8	75.6	0	0	0	0	111	H342 L423 C425 L431 S432	H342-S428 VanDerWaalsContact NE2-CA 3.31Å; H342-S428 WeakPolarHBondContact NE2-CA 3.49Å; H342-S428 WeakPolarHBondContact NE2-CB 3.35Å; L423-S428 WeakPolarHBondContact O-CB 3.18Å; L423-S428 PolarHBondContact O-OG 3.5Å; C425-S428 PolarHBondContact N-OG 2.87Å; C425-S428 WeakPolarHBondContact O-CB 3.25Å; C425-S428 PolarHBondContact O-N 3.23Å; C425-S428 PolarHBondContact O-OG 2.99Å; S428-L431 PolarHBondContact O-N 3.13Å; S428-S432 PolarHBondContact O-N 3.31Å
429	M	77.4	Confident	74.1	Confident	102 Å²	102	74.8 Å²	74.8	50%	0.502	39%	0.387	S	S	.	.	H	α-helix	trans	-64.3	-41.4	173.6	-67.5	-64	-148.9	0	0	111.9	C425 Y426 Q427 L431 S432 V433	C425-M429 PolarHBondContact O-N 2.9Å; Y426-M429 PolarHBondContact O-N 2.83Å; Q427-M429 VanDerWaalsContact C-N 3.34Å; M429-L431 VanDerWaalsContact C-N 3.33Å; M429-L431 PolarHBondContact O-N 3.05Å; M429-S432 PolarHBondContact O-N 3.25Å; M429-S432 PolarHBondContact O-OG 3.42Å; M429-V433 WeakPolarHBondContact O-CG2 3.06Å; M429-V433 PolarHBondContact O-N 3.02Å
430	L	81.7	Confident	75.9	Confident	95 Å²	95	78.6 Å²	78.6	50%	0.497	39%	0.392	S	S	.	.	H	α-helix	trans	-65.9	-39.4	177.3	-169.3	152	0	0	0	111.3	M363 Y426 Q427 V433 V434	M363-L430 HydrophobicContact CE-CD2 3.34Å; M363-L430 HydrophobicContact CG-CD2 4.09Å; M363-L430 HydrophobicContact SD-CD2 4.05Å; Y426-L430 WeakPolarHBondContact O-CB 3.36Å; Y426-L430 PolarHBondContact O-N 3.48Å; Q427-L430 PolarHBondContact O-N 3.05Å; L430-V433 PolarHBondContact O-N 3.44Å; L430-V434 HydrophobicContact CD2-CG2 4.27Å; L430-V434 WeakPolarHBondContact O-CG2 3.28Å; L430-V434 PolarHBondContact O-N 2.67Å
431	L	84.5	Confident	77.7	Confident	2 Å²	2	72.8 Å²	72.8	1%	0.01	37%	0.374	C	S	.	.	H	α-helix	trans	-66.1	-40.6	175.1	-166.2	70.3	0	0	0	112.1	Y338 H342 I345 M363 V366 Q427 S428 M429 V433 V434 Y435	Y338-L431 HydrophobicContact CE2-CD2 4.32Å; H342-L431 HydrophobicContact CB-CD2 3.92Å; I345-L431 HydrophobicContact CD1-CD1 3.53Å; M363-L431 HydrophobicContact CE-CB 4.31Å; M363-L431 HydrophobicContact CE-CD1 3.43Å; M363-L431 VanDerWaalsContact CE-CD1 3.43Å; M363-L431 HydrophobicContact CE-CG 4.44Å; M363-L431 HydrophobicContact SD-CD1 4.14Å; V366-L431 HydrophobicContact CG1-CD1 4.12Å; V366-L431 HydrophobicContact CG2-CD1 4.27Å; Q427-L431 WeakPolarHBondContact O-CB 3.4Å; Q427-L431 PolarHBondContact O-N 3.42Å; S428-L431 PolarHBondContact O-N 3.13Å; M429-L431 VanDerWaalsContact C-N 3.33Å; M429-L431 PolarHBondContact O-N 3.05Å; L431-V433 PolarHBondContact O-N 2.98Å; L431-V434 PolarHBondContact O-N 3.1Å; L431-V434 VanDerWaalsContact O-N 3.17Å; L431-Y435 HydrophobicContact CB-CE2 4.43Å; L431-Y435 HydrophobicContact CD1-CE2 4.2Å; L431-Y435 HydrophobicContact CD2-CE2 3.59Å; L431-Y435 WeakPolarHBondContact CD2-OH 3.28Å; L431-Y435 HydrophobicContact CG-CD2 4.09Å; L431-Y435 HydrophobicContact CG-CE2 3.39Å; L431-Y435 WeakPolarHBondContact O-CD2 3.44Å; L431-Y435 PolarHBondContact O-N 3.14Å
432	S	82.7	Confident	79.1	Confident	51 Å²	51	70 Å²	70	36%	0.357	36%	0.357	S	S	.	.	H	α-helix	trans	-63.1	-40.8	175.8	74.3	0	0	0	0	112.1	S428 M429 V434 Y435 M436	S428-S432 PolarHBondContact O-N 3.31Å; M429-S432 PolarHBondContact O-N 3.25Å; M429-S432 PolarHBondContact O-OG 3.42Å; S432-V434 VanDerWaalsContact C-N 3.33Å; S432-V434 PolarHBondContact O-N 3.16Å; S432-Y435 PolarHBondContact O-N 3.24Å; S432-M436 WeakPolarHBondContact O-CG 3.29Å; S432-M436 PolarHBondContact O-N 3.21Å
433	V	87.3	Confident	80.3	Confident	86 Å²	86	68.5 Å²	68.5	52%	0.521	35%	0.345	S	S	.	.	H	α-helix	trans	-59.8	-43.9	172	172.6	0	0	0	0	110.9	M429 L430 L431 Y435 M436 V437	M429-V433 WeakPolarHBondContact O-CG2 3.06Å; M429-V433 PolarHBondContact O-N 3.02Å; L430-V433 PolarHBondContact O-N 3.44Å; L431-V433 PolarHBondContact O-N 2.98Å; V433-Y435 VanDerWaalsContact C-N 3.35Å; V433-Y435 PolarHBondContact O-N 3.02Å; V433-M436 PolarHBondContact O-N 3.26Å; V433-V437 HydrophobicContact CG1-CG2 4.24Å; V433-V437 WeakPolarHBondContact O-CG2 3.1Å; V433-V437 PolarHBondContact O-N 3.13Å
434	V	90.1	Very high	81.3	Confident	22 Å²	22	66.5 Å²	66.5	13%	0.133	35%	0.346	C	S	.	.	H	α-helix	trans	-63.5	-39	177.2	170.4	0	0	0	0	112.2	M363 V366 L367 L430 L431 S432 V437 G438	M363-V434 HydrophobicContact CB-CG2 4.48Å; M363-V434 HydrophobicContact CE-CB 3.79Å; M363-V434 HydrophobicContact CE-CG1 4.15Å; M363-V434 HydrophobicContact CE-CG2 3.46Å; M363-V434 VanDerWaalsContact CE-CG2 3.46Å; V366-V434 HydrophobicContact CB-CG1 4.35Å; V366-V434 HydrophobicContact CG1-CG1 4.23Å; L367-V434 HydrophobicContact CB-CG1 4.03Å; L430-V434 HydrophobicContact CD2-CG2 4.27Å; L430-V434 WeakPolarHBondContact O-CG2 3.28Å; L430-V434 PolarHBondContact O-N 2.67Å; L431-V434 PolarHBondContact O-N 3.1Å; L431-V434 VanDerWaalsContact O-N 3.17Å; S432-V434 VanDerWaalsContact C-N 3.33Å; S432-V434 PolarHBondContact O-N 3.16Å; V434-V437 PolarHBondContact O-N 2.66Å; V434-G438 PolarHBondContact O-N 2.65Å
435	Y	89.5	Confident	82.1	Confident	4 Å²	4	63.1 Å²	63.1	2%	0.016	33%	0.331	C	S	.	.	H	α-helix	trans	-61	-44.1	172.5	-69.4	-57	0	0	0	111.6	G331 Y338 V366 V370 L431 S432 V433 G438 L439	G331-Y435 WeakPolarHBondContact O-CE1 3.46Å; G331-Y435 PolarHBondContact O-OH 3.4Å; Y338-Y435 HydrophobicContact CD2-CE2 4.14Å; Y338-Y435 HydrophobicContact CE2-CE2 4.15Å; V366-Y435 HydrophobicContact CG1-CD1 4.1Å; V366-Y435 HydrophobicContact CG1-CE1 3.46Å; V366-Y435 VanDerWaalsContact CG1-CE1 3.46Å; V370-Y435 HydrophobicContact CG2-CD1 3.54Å; V370-Y435 HydrophobicContact CG2-CE1 4.06Å; L431-Y435 HydrophobicContact CB-CE2 4.43Å; L431-Y435 HydrophobicContact CD1-CE2 4.2Å; L431-Y435 HydrophobicContact CD2-CE2 3.59Å; L431-Y435 WeakPolarHBondContact CD2-OH 3.28Å; L431-Y435 HydrophobicContact CG-CD2 4.09Å; L431-Y435 HydrophobicContact CG-CE2 3.39Å; L431-Y435 WeakPolarHBondContact O-CD2 3.44Å; L431-Y435 PolarHBondContact O-N 3.14Å; S432-Y435 PolarHBondContact O-N 3.24Å; V433-Y435 VanDerWaalsContact C-N 3.35Å; V433-Y435 PolarHBondContact O-N 3.02Å; Y435-G438 PolarHBondContact O-N 3.36Å; Y435-L439 WeakPolarHBondContact O-CG 3.19Å; Y435-L439 PolarHBondContact O-N 2.93Å
436	M	88.9	Confident	82.2	Confident	105 Å²	105	61.5 Å²	61.5	52%	0.517	32%	0.32	S	S	.	.	H	α-helix	trans	-65.2	-43.3	178.2	-65.8	-61.1	-67	0	0	112.4	S432 V433 L439 M440	S432-M436 WeakPolarHBondContact O-CG 3.29Å; S432-M436 PolarHBondContact O-N 3.21Å; V433-M436 PolarHBondContact O-N 3.26Å; M436-L439 WeakPolarHBondContact O-CB 3.39Å; M436-L439 PolarHBondContact O-N 2.91Å; M436-L439 HydrophobicContact SD-CD1 4.41Å; M436-M440 WeakPolarHBondContact O-CG 3.28Å; M436-M440 PolarHBondContact O-N 3.38Å
437	V	90.8	Very high	81.9	Confident	69 Å²	69	55.2 Å²	55.2	42%	0.418	30%	0.303	S	S	.	.	H	α-helix	trans	-63.5	-44.7	175.1	174.7	0	0	0	0	110.4	L367 V433 V434 L439 M440 V441	L367-V437 HydrophobicContact CD1-CG1 3.86Å; V433-V437 HydrophobicContact CG1-CG2 4.24Å; V433-V437 WeakPolarHBondContact O-CG2 3.1Å; V433-V437 PolarHBondContact O-N 3.13Å; V434-V437 PolarHBondContact O-N 2.66Å; V437-L439 VanDerWaalsContact C-N 3.26Å; V437-L439 PolarHBondContact O-N 3.03Å; V437-M440 PolarHBondContact O-N 2.82Å; V437-V441 HydrophobicContact CG1-CG2 4.22Å; V437-V441 WeakPolarHBondContact O-CB 2.9Å; V437-V441 VanDerWaalsContact O-CG2 3.29Å; V437-V441 WeakPolarHBondContact O-CG2 3.38Å; V437-V441 PolarHBondContact O-N 3.13Å
438	G	88.1	Confident	81.4	Confident	0 Å²	0	54.7 Å²	54.7	0%	0	31%	0.311	C	S	.	.	H	α-helix	trans	-59.2	-38.1	175.5	0	0	0	0	0	112.5	V371 V434 Y435 G442	V371-G438 WeakPolarHBondContact CG2-O 3.29Å; V434-G438 PolarHBondContact O-N 2.65Å; Y435-G438 PolarHBondContact O-N 3.36Å; G438-G442 PolarHBondContact O-N 3.46Å
439	L	87.8	Confident	80.4	Confident	29 Å²	29	59.6 Å²	59.6	15%	0.152	33%	0.329	C	S	.	.	H	α-helix	trans	-62.1	-52.3	173.3	-74.2	-179.4	0	0	0	111.5	F327 F332 V370 L374 Y435 M436 V437 V441 G442 F443	F327-L439 HydrophobicContact CE1-CD2 3.69Å; F327-L439 HydrophobicContact CZ-CD2 4.35Å; F332-L439 HydrophobicContact CE2-CD1 3.77Å; F332-L439 HydrophobicContact CE2-CD2 4.32Å; F332-L439 HydrophobicContact CE2-CG 4.25Å; F332-L439 HydrophobicContact CZ-CD1 4.28Å; V370-L439 HydrophobicContact CG1-CD2 3.89Å; V370-L439 HydrophobicContact CG1-CG 4.14Å; L374-L439 VanDerWaalsContact CD1-CA 3.49Å; L374-L439 HydrophobicContact CD1-CB 4.24Å; L374-L439 HydrophobicContact CD1-CD2 3.51Å; L374-L439 HydrophobicContact CD1-CG 4.42Å; L374-L439 WeakPolarHBondContact CD1-O 3.32Å; L374-L439 HydrophobicContact CD2-CD2 3.96Å; L374-L439 HydrophobicContact CG-CD2 3.85Å; Y435-L439 WeakPolarHBondContact O-CG 3.19Å; Y435-L439 PolarHBondContact O-N 2.93Å; M436-L439 WeakPolarHBondContact O-CB 3.39Å; M436-L439 PolarHBondContact O-N 2.91Å; M436-L439 HydrophobicContact SD-CD1 4.41Å; V437-L439 VanDerWaalsContact C-N 3.26Å; V437-L439 PolarHBondContact O-N 3.03Å; L439-V441 VanDerWaalsContact C-N 3.32Å; L439-V441 PolarHBondContact O-N 3.16Å; L439-G442 PolarHBondContact O-N 3.09Å; L439-F443 VanDerWaalsContact O-CD2 3.27Å; L439-F443 WeakPolarHBondContact O-CD2 3.42Å; L439-F443 PolarHBondContact O-N 3.01Å
440	M	87.4	Confident	78.6	Confident	135 Å²	135	62 Å²	62	67%	0.665	33%	0.333	S	S	*	.	H	α-helix	trans	-57.6	-44.8	179.9	-68	-67.4	177.6	0	0	112.2	M436 V437 G444	M436-M440 WeakPolarHBondContact O-CG 3.28Å; M436-M440 PolarHBondContact O-N 3.38Å; V437-M440 PolarHBondContact O-N 2.82Å; M440-G444 PolarHBondContact O-N 2.65Å
441	V	86.7	Confident	76.2	Confident	54 Å²	54	65.4 Å²	65.4	33%	0.327	34%	0.344	S	S	.	.	H	α-helix	trans	-63.7	-46.1	177	173.2	0	0	0	0	110.6	V371 V437 L439 G444 F445	V371-V441 HydrophobicContact CG1-CG1 4.4Å; V371-V441 HydrophobicContact CG2-CB 4.01Å; V371-V441 HydrophobicContact CG2-CG1 3.76Å; V437-V441 HydrophobicContact CG1-CG2 4.22Å; V437-V441 WeakPolarHBondContact O-CB 2.9Å; V437-V441 VanDerWaalsContact O-CG2 3.29Å; V437-V441 WeakPolarHBondContact O-CG2 3.38Å; V437-V441 PolarHBondContact O-N 3.13Å; L439-V441 VanDerWaalsContact C-N 3.32Å; L439-V441 PolarHBondContact O-N 3.16Å; V441-G444 PolarHBondContact O-N 3.49Å; V441-G444 VanDerWaalsContact O-N 3.16Å; V441-F445 HydrophobicContact CG1-CD2 3.75Å; V441-F445 HydrophobicContact CG1-CE2 3.51Å; V441-F445 VanDerWaalsContact O-CD2 3.24Å; V441-F445 WeakPolarHBondContact O-CD2 3.26Å; V441-F445 PolarHBondContact O-N 3.1Å
442	G	82.7	Confident	73.8	Confident	0 Å²	0	69.4 Å²	69.4	0%	0	36%	0.363	C	S	.	.	H	α-helix	trans	-62.7	-43.1	178.8	0	0	0	0	0	113.3	G438 L439 G444 F445 V446	G438-G442 PolarHBondContact O-N 3.46Å; L439-G442 PolarHBondContact O-N 3.09Å; G442-G444 VanDerWaalsContact C-N 3.32Å; G442-G444 PolarHBondContact O-N 2.75Å; G442-F445 PolarHBondContact O-N 2.87Å; G442-V446 VanDerWaalsContact O-CG2 3.25Å; G442-V446 WeakPolarHBondContact O-CG2 3.47Å; G442-V446 PolarHBondContact O-N 2.97Å
443	F	81.8	Confident	71.4	Confident	97 Å²	97	72.7 Å²	72.7	43%	0.425	39%	0.387	S	S	.	.	H	α-helix	trans	-59.9	-42.3	171.4	-89	-79.5	0	0	0	111.8	L374 F378 L439 F445 V446 V447	L374-F443 HydrophobicContact CD1-CD2 4.22Å; L374-F443 HydrophobicContact CD2-CD2 4.33Å; L374-F443 HydrophobicContact CD2-CE2 3.97Å; L374-F443 HydrophobicContact CD2-CZ 4.45Å; F378-F443 HydrophobicContact CE1-CE1 4.44Å; F378-F443 HydrophobicContact CE2-CD1 4.08Å; F378-F443 AromaticContact CE2-CE1 3.8Å; F378-F443 HydrophobicContact CE2-CE1 3.8Å; F378-F443 HydrophobicContact CE2-CZ 4.16Å; F378-F443 AromaticContact CZ-CD1 3.97Å; F378-F443 HydrophobicContact CZ-CD1 3.97Å; F378-F443 AromaticContact CZ-CE1 3.34Å; F378-F443 HydrophobicContact CZ-CE1 3.34Å; F378-F443 AromaticContact CZ-CZ 3.84Å; F378-F443 HydrophobicContact CZ-CZ 3.84Å; L439-F443 VanDerWaalsContact O-CD2 3.27Å; L439-F443 WeakPolarHBondContact O-CD2 3.42Å; L439-F443 PolarHBondContact O-N 3.01Å; F443-F445 PolarHBondContact O-N 3.23Å; F443-V446 PolarHBondContact O-N 2.73Å; F443-V447 VanDerWaalsContact O-CG2 3.32Å; F443-V447 WeakPolarHBondContact O-CG2 3.34Å; F443-V447 PolarHBondContact O-N 3.37Å
444	G	78.2	Confident	68.6	Low	48 Å²	48	72 Å²	72	50%	0.495	40%	0.397	S	S	.	.	H	α-helix	trans	-58.6	-44.5	175.5	0	0	0	0	0	113.1	M440 V441 G442 G448	M440-G444 PolarHBondContact O-N 2.65Å; V441-G444 PolarHBondContact O-N 3.49Å; V441-G444 VanDerWaalsContact O-N 3.16Å; G442-G444 VanDerWaalsContact C-N 3.32Å; G442-G444 PolarHBondContact O-N 2.75Å; G444-G448 PolarHBondContact O-N 2.67Å
445	F	74.2	Confident	65.6	Low	107 Å²	107	74 Å²	74	47%	0.469	41%	0.411	S	S	.	.	H	α-helix	trans	-61.9	-46	174.9	-84.3	-72.4	0	0	0	112	V371 V441 G442 F443 G448 Y449	V371-F445 HydrophobicContact CG1-CD2 3.76Å; V371-F445 HydrophobicContact CG1-CE2 4.18Å; V441-F445 HydrophobicContact CG1-CD2 3.75Å; V441-F445 HydrophobicContact CG1-CE2 3.51Å; V441-F445 VanDerWaalsContact O-CD2 3.24Å; V441-F445 WeakPolarHBondContact O-CD2 3.26Å; V441-F445 PolarHBondContact O-N 3.1Å; G442-F445 PolarHBondContact O-N 2.87Å; F443-F445 PolarHBondContact O-N 3.23Å; F445-G448 PolarHBondContact O-N 3.09Å; F445-Y449 WeakPolarHBondContact O-CD2 3.46Å; F445-Y449 PolarHBondContact O-N 3.43Å; F445-Y449 VanDerWaalsContact O-N 3.13Å
446	V	70.9	Confident	62.8	Low	13 Å²	13	80.7 Å²	80.7	8%	0.079	45%	0.447	C	S	.	.	H	α-helix	trans	-62.6	-53.6	-179.2	172.8	0	0	0	0	110.2	F378 G442 F443 G448 Y449 W450	F378-V446 HydrophobicContact CB-CG1 3.78Å; F378-V446 HydrophobicContact CB-CG2 4.21Å; F378-V446 HydrophobicContact CD1-CG1 4.15Å; F378-V446 HydrophobicContact CD2-CB 4.06Å; F378-V446 HydrophobicContact CD2-CG1 3.69Å; F378-V446 HydrophobicContact CD2-CG2 3.52Å; F378-V446 HydrophobicContact CE2-CG1 4.32Å; F378-V446 HydrophobicContact CE2-CG2 4.25Å; F378-V446 HydrophobicContact CG-CB 4.44Å; F378-V446 HydrophobicContact CG-CG1 3.6Å; F378-V446 HydrophobicContact CG-CG2 4.13Å; G442-V446 VanDerWaalsContact O-CG2 3.25Å; G442-V446 WeakPolarHBondContact O-CG2 3.47Å; G442-V446 PolarHBondContact O-N 2.97Å; F443-V446 PolarHBondContact O-N 2.73Å; V446-G448 PolarHBondContact O-N 3.15Å; V446-Y449 WeakPolarHBondContact O-CA 3.47Å; V446-Y449 WeakPolarHBondContact O-CB 3.48Å; V446-Y449 PolarHBondContact O-N 3.02Å; V446-W450 VanDerWaalsContact O-CD1 3.24Å; V446-W450 PolarHBondContact O-N 2.69Å
447	V	64.5	Low	59.9	Low	83 Å²	83	84.8 Å²	84.8	50%	0.503	46%	0.462	S	S	.	.	H	α-helix	trans	-58.4	-36.5	179.8	174.6	0	0	0	0	111.5	F443 Y449 W450 K451	F443-V447 VanDerWaalsContact O-CG2 3.32Å; F443-V447 WeakPolarHBondContact O-CG2 3.34Å; F443-V447 PolarHBondContact O-N 3.37Å; V447-Y449 VanDerWaalsContact C-N 3.35Å; V447-Y449 PolarHBondContact O-N 2.66Å; V447-W450 PolarHBondContact O-N 2.76Å; V447-K451 PolarHBondContact O-N 2.75Å
448	G	59.6	Low	56.8	Low	38 Å²	38	90.6 Å²	90.6	39%	0.392	48%	0.482	S	S	.	.	H	α-helix	trans	-58	-43.8	172.4	0	0	0	0	0	112.9	G444 F445 V446 M452	G444-G448 PolarHBondContact O-N 2.67Å; F445-G448 PolarHBondContact O-N 3.09Å; V446-G448 PolarHBondContact O-N 3.15Å; G448-M452 WeakPolarHBondContact O-CG 3.32Å
449	Y	54.5	Low	54	Low	112 Å²	112	93.4 Å²	93.4	44%	0.439	51%	0.511	S	S	.	.	H	α-helix	trans	-69.5	-39.1	176.9	-89.5	-80.1	0	0	0	113.4	F445 V446 V447 K451 M452	F445-Y449 WeakPolarHBondContact O-CD2 3.46Å; F445-Y449 PolarHBondContact O-N 3.43Å; F445-Y449 VanDerWaalsContact O-N 3.13Å; V446-Y449 WeakPolarHBondContact O-CA 3.47Å; V446-Y449 WeakPolarHBondContact O-CB 3.48Å; V446-Y449 PolarHBondContact O-N 3.02Å; V447-Y449 VanDerWaalsContact C-N 3.35Å; V447-Y449 PolarHBondContact O-N 2.66Å; Y449-K451 PolarHBondContact O-N 3.49Å; Y449-M452 PolarHBondContact O-N 3.45Å
450	W	39.5	Very low	51.5	Low	152 Å²	152	95.2 Å²	95.2	58%	0.576	54%	0.537	S	S	*	.	H	α-helix	trans	-66.3	-25.1	178.5	-78	80.7	0	0	0	112.9	V446 V447 M452	V446-W450 VanDerWaalsContact O-CD1 3.24Å; V446-W450 PolarHBondContact O-N 2.69Å; V447-W450 PolarHBondContact O-N 2.76Å; W450-M452 VanDerWaalsContact C-N 3.35Å
451	K	31.2	Very low	49	Very low	166 Å²	166	96.3 Å²	96.3	72%	0.722	54%	0.542	S	S	*	.	G	3₁₀ helix	trans	-81.6	-6.8	172.4	-89.4	-177.2	174.1	178.6	0	114.6	V447 Y449	V447-K451 PolarHBondContact O-N 2.75Å; Y449-K451 PolarHBondContact O-N 3.49Å
452	M	33.2	Very low	46.5	Very low	86 Å²	86	97.6 Å²	97.6	42%	0.424	55%	0.547	S	S	.	.	G	3₁₀ helix	trans	-96.6	19.6	-174.9	-75.6	-142.8	81.8	0	0	115.3	G448 Y449 W450	G448-M452 WeakPolarHBondContact O-CG 3.32Å; Y449-M452 PolarHBondContact O-N 3.45Å; W450-M452 VanDerWaalsContact C-N 3.35Å
453	S	32.4	Very low	44.3	Very low	121 Å²	121	101.2 Å²	101.2	85%	0.846	57%	0.573	S	S	*	*	G	3₁₀ helix	trans	-98.2	-3.2	169.9	70.1	0	0	0	0	114.6
454	G	28.8	Very low	42.1	Very low	72 Å²	72	102.1 Å²	102.1	74%	0.742	58%	0.582	S	S	*	*	S	Bend	trans	-139.1	12.5	-174.6	0	0	0	0	0	116.6
455	C	26.8	Very low	40.4	Very low	64 Å²	64	103.1 Å²	103.1	43%	0.432	58%	0.578	S	S	.	*			trans	-144.3	70.5	-174.7	-142.9	0	0	0	0	113.4	K457	C455-K457 PolarHBondContact O-N 3.43Å
456	D	30.3	Very low	39.2	Very low	143 Å²	143	102.3 Å²	102.3	77%	0.765	58%	0.581	S	S	*	*	S	Bend	trans	-73.6	3.1	173	-75.7	-25	0	0	0	113.9
457	K	27.9	Very low	38	Very low	191 Å²	191	106.5 Å²	106.5	83%	0.83	60%	0.603	S	S	*	*	S	Bend	trans	-140.1	9.5	-167.4	-79.2	-175.1	179.4	171.7	0	119.1	C455	C455-K457 PolarHBondContact O-N 3.43Å
458	F	25.9	Very low	37.4	Very low	191 Å²	191	108.7 Å²	108.7	84%	0.838	61%	0.606	S	S	*	*	S	Bend	trans	-126.4	114.6	179.6	-105.4	-94.7	0	0	0	115.1
459	G	28.8	Very low	36.9	Very low	60 Å²	60	111.6 Å²	111.6	62%	0.619	61%	0.608	S	S	*	*	S	Bend	trans	84.4	78.8	143.1	0	0	0	0	0	117.6	M461	G459-M461 PolarHBondContact O-N 3.21Å
460	G	36	Very low	36.9	Very low	67 Å²	67	107.7 Å²	107.7	69%	0.691	60%	0.601	S	S	*	*	S	Bend	trans	66	-20.8	144.6	0	0	0	0	0	120.3	S463	G460-S463 PolarHBondContact O-OG 3.12Å
461	M	34.1	Very low	37.7	Very low	157 Å²	157	104.1 Å²	104.1	77%	0.773	59%	0.593	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.1	-12.1	-174.5	-64	-174.7	93.9	0	0	113.6	G459 S463	G459-M461 PolarHBondContact O-N 3.21Å; M461-S463 PolarHBondContact O-N 3.46Å
462	N	34.8	Very low	39	Very low	81 Å²	81	97.7 Å²	97.7	43%	0.433	57%	0.566	S	S	.	*	H	α-helix	trans	-65.3	-20.7	168.4	-82.3	-13.5	0	0	0	112.1	V466	N462-V466 HydrophobicContact CB-CG2 4.49Å; N462-V466 WeakPolarHBondContact O-CA 3.17Å; N462-V466 WeakPolarHBondContact O-CB 3.26Å; N462-V466 WeakPolarHBondContact O-CG2 3.07Å; N462-V466 PolarHBondContact O-N 3.33Å
463	S	37.1	Very low	40.2	Very low	76 Å²	76	100.6 Å²	100.6	53%	0.531	57%	0.573	S	S	.	*	H	α-helix	trans	-65.3	-45	179.1	64.1	0	0	0	0	111.8	G460 M461 L467	G460-S463 PolarHBondContact O-OG 3.12Å; M461-S463 PolarHBondContact O-N 3.46Å; S463-L467 WeakPolarHBondContact O-CA 3.42Å; S463-L467 WeakPolarHBondContact O-CB 3.1Å; S463-L467 PolarHBondContact O-N 3.32Å
464	L	35.7	Very low	41.4	Very low	117 Å²	117	98.2 Å²	98.2	61%	0.613	55%	0.554	S	S	*	*	H	α-helix	trans	-71.8	-37.3	179.5	-90.3	160.4	0	0	0	112.8	L467 F468	L464-L467 PolarHBondContact O-N 3.03Å; L464-F468 WeakPolarHBondContact O-CB 3.4Å; L464-F468 PolarHBondContact O-N 2.7Å
465	V	42.3	Very low	42.9	Very low	68 Å²	68	100.4 Å²	100.4	41%	0.412	54%	0.543	S	S	.	.	H	α-helix	trans	-75	-34	176.6	178.3	0	0	0	0	111.4	K469	V465-K469 WeakPolarHBondContact O-CB 3.35Å; V465-K469 PolarHBondContact O-N 3.24Å
466	V	48.6	Very low	44.3	Very low	91 Å²	91	99.3 Å²	99.3	55%	0.552	54%	0.536	S	S	*	.	H	α-helix	trans	-73.5	-30	171.3	173.6	0	0	0	0	111.2	N462 G470	N462-V466 HydrophobicContact CB-CG2 4.49Å; N462-V466 WeakPolarHBondContact O-CA 3.17Å; N462-V466 WeakPolarHBondContact O-CB 3.26Å; N462-V466 WeakPolarHBondContact O-CG2 3.07Å; N462-V466 PolarHBondContact O-N 3.33Å; V466-G470 VanDerWaalsContact O-CA 3.26Å; V466-G470 WeakPolarHBondContact O-CA 3.3Å; V466-G470 PolarHBondContact O-N 2.71Å
467	L	46.4	Very low	45.5	Very low	101 Å²	101	96.5 Å²	96.5	53%	0.529	52%	0.521	S	S	.	.	H	α-helix	trans	-77.4	-35.8	174.5	-162.2	156.8	0	0	0	110.7	S463 L464 G470 L471	S463-L467 WeakPolarHBondContact O-CA 3.42Å; S463-L467 WeakPolarHBondContact O-CB 3.1Å; S463-L467 PolarHBondContact O-N 3.32Å; L464-L467 PolarHBondContact O-N 3.03Å; L467-G470 PolarHBondContact O-N 3.25Å; L467-L471 HydrophobicContact CD2-CD1 3.51Å; L467-L471 HydrophobicContact CD2-CG 4.05Å; L467-L471 WeakPolarHBondContact O-CB 3.06Å; L467-L471 VanDerWaalsContact O-CG 3.27Å; L467-L471 WeakPolarHBondContact O-CG 3.43Å; L467-L471 PolarHBondContact O-N 3.24Å
468	F	51	Low	46.8	Very low	129 Å²	129	92.5 Å²	92.5	57%	0.566	51%	0.508	S	S	*	.	H	α-helix	trans	-70.4	-42.6	169.1	-112.6	-88.6	0	0	0	111.9	L464 G470 M472	L464-F468 WeakPolarHBondContact O-CB 3.4Å; L464-F468 PolarHBondContact O-N 2.7Å; F468-G470 VanDerWaalsContact C-N 3.3Å; F468-M472 WeakPolarHBondContact O-CA 3.07Å; F468-M472 WeakPolarHBondContact O-CB 3.19Å; F468-M472 WeakPolarHBondContact O-CG 3.47Å; F468-M472 PolarHBondContact O-N 3.12Å
469	K	50.6	Low	48	Very low	99 Å²	99	85.5 Å²	85.5	43%	0.43	48%	0.479	S	S	.	.	H	α-helix	trans	-61.8	-40.8	170.3	-90.7	179.4	172.3	174	0	110.7	V465 M472 Y473	V465-K469 WeakPolarHBondContact O-CB 3.35Å; V465-K469 PolarHBondContact O-N 3.24Å; K469-M472 CarbonylContact O-C 3.51Å; K469-M472 PolarHBondContact O-N 2.9Å; K469-Y473 HydrophobicContact CB-CD2 4.19Å; K469-Y473 HydrophobicContact CB-CE2 4.25Å; K469-Y473 HydrophobicContact CG-CE2 4.48Å; K469-Y473 VanDerWaalsContact O-CB 3.26Å; K469-Y473 WeakPolarHBondContact O-CB 3.39Å; K469-Y473 WeakPolarHBondContact O-CD2 3.14Å; K469-Y473 PolarHBondContact O-N 3.11Å
470	G	53.9	Low	48.9	Very low	29 Å²	29	84.7 Å²	84.7	30%	0.299	46%	0.464	S	S	.	.	H	α-helix	trans	-66.9	-46.5	179.3	0	0	0	0	0	111.6	V466 L467 F468 M472 Y473 T474	V466-G470 VanDerWaalsContact O-CA 3.26Å; V466-G470 WeakPolarHBondContact O-CA 3.3Å; V466-G470 PolarHBondContact O-N 2.71Å; L467-G470 PolarHBondContact O-N 3.25Å; F468-G470 VanDerWaalsContact C-N 3.3Å; G470-M472 VanDerWaalsContact C-N 3.33Å; G470-Y473 PolarHBondContact O-N 2.86Å; G470-T474 WeakPolarHBondContact O-CB 3.44Å; G470-T474 VanDerWaalsContact O-CG2 3.3Å; G470-T474 WeakPolarHBondContact O-CG2 3.35Å; G470-T474 PolarHBondContact O-N 3.36Å; G470-T474 PolarHBondContact O-OG1 3.33Å; G470-T474 VanDerWaalsContact O-OG1 3.06Å
471	L	55.9	Low	49.3	Very low	77 Å²	77	89.6 Å²	89.6	40%	0.403	47%	0.466	S	S	.	.	H	α-helix	trans	-61.3	-42.3	170.1	-79.9	170.1	0	0	0	110.8	L467 T474 F475	L467-L471 HydrophobicContact CD2-CD1 3.51Å; L467-L471 HydrophobicContact CD2-CG 4.05Å; L467-L471 WeakPolarHBondContact O-CB 3.06Å; L467-L471 VanDerWaalsContact O-CG 3.27Å; L467-L471 WeakPolarHBondContact O-CG 3.43Å; L467-L471 PolarHBondContact O-N 3.24Å; L471-T474 VanDerWaalsContact CA-OG1 3.32Å; L471-T474 WeakPolarHBondContact CA-OG1 3.17Å; L471-T474 PolarHBondContact O-N 3.35Å; L471-T474 PolarHBondContact O-OG1 2.68Å; L471-F475 HydrophobicContact CB-CD2 4.46Å; L471-F475 HydrophobicContact CD2-CE2 4.47Å; L471-F475 WeakPolarHBondContact O-CA 3.48Å; L471-F475 WeakPolarHBondContact O-CB 3.45Å; L471-F475 WeakPolarHBondContact O-CD2 3Å; L471-F475 PolarHBondContact O-N 2.75Å
472	M	58.8	Low	49.8	Very low	32 Å²	32	85.6 Å²	85.6	16%	0.158	45%	0.451	C	S	.	.	H	α-helix	trans	-68.9	-34	177.7	-78.2	-83.8	-19.7	0	0	112.6	Y240 I243 F468 K469 G470 S476	Y240-M472 HydrophobicContact CD2-CE 3.82Å; I243-M472 HydrophobicContact CD1-CB 4.05Å; I243-M472 HydrophobicContact CD1-CE 3.56Å; I243-M472 HydrophobicContact CD1-CG 3.36Å; I243-M472 HydrophobicContact CD1-SD 3.29Å; I243-M472 WeakPolarHBondContact CD1-SD 3.32Å; F468-M472 WeakPolarHBondContact O-CA 3.07Å; F468-M472 WeakPolarHBondContact O-CB 3.19Å; F468-M472 WeakPolarHBondContact O-CG 3.47Å; F468-M472 PolarHBondContact O-N 3.12Å; K469-M472 CarbonylContact O-C 3.51Å; K469-M472 PolarHBondContact O-N 2.9Å; G470-M472 VanDerWaalsContact C-N 3.33Å; M472-S476 WeakPolarHBondContact O-CA 3.05Å; M472-S476 WeakPolarHBondContact O-CB 3.48Å; M472-S476 PolarHBondContact O-N 3.32Å; M472-S476 PolarHBondContact O-OG 3.06Å
473	Y	59.3	Low	50.3	Low	146 Å²	146	83.4 Å²	83.4	57%	0.573	44%	0.44	S	S	*	.	H	α-helix	trans	-73.5	-42.7	174.1	-84.5	-63.1	0	0	0	109.9	K469 G470 S476 D477	K469-Y473 HydrophobicContact CB-CD2 4.19Å; K469-Y473 HydrophobicContact CB-CE2 4.25Å; K469-Y473 HydrophobicContact CG-CE2 4.48Å; K469-Y473 VanDerWaalsContact O-CB 3.26Å; K469-Y473 WeakPolarHBondContact O-CB 3.39Å; K469-Y473 WeakPolarHBondContact O-CD2 3.14Å; K469-Y473 PolarHBondContact O-N 3.11Å; G470-Y473 PolarHBondContact O-N 2.86Å; Y473-S476 WeakPolarHBondContact CA-OG 3.1Å; Y473-S476 CarbonylContact O-C 3.52Å; Y473-S476 PolarHBondContact O-N 2.96Å; Y473-S476 PolarHBondContact O-OG 2.76Å; Y473-D477 WeakPolarHBondContact O-CA 3.32Å; Y473-D477 WeakPolarHBondContact O-CB 3.27Å; Y473-D477 PolarHBondContact O-N 2.77Å
474	T	56.9	Low	50.3	Low	72 Å²	72	87.6 Å²	87.6	44%	0.442	45%	0.449	S	S	.	.	H	α-helix	trans	-67.1	-37.3	173.2	57.5	0	0	0	0	111.4	G470 L471 D477 L478	G470-T474 WeakPolarHBondContact O-CB 3.44Å; G470-T474 VanDerWaalsContact O-CG2 3.3Å; G470-T474 WeakPolarHBondContact O-CG2 3.35Å; G470-T474 PolarHBondContact O-N 3.36Å; G470-T474 PolarHBondContact O-OG1 3.33Å; G470-T474 VanDerWaalsContact O-OG1 3.06Å; L471-T474 VanDerWaalsContact CA-OG1 3.32Å; L471-T474 WeakPolarHBondContact CA-OG1 3.17Å; L471-T474 PolarHBondContact O-N 3.35Å; L471-T474 PolarHBondContact O-OG1 2.68Å; T474-D477 PolarHBondContact O-N 3.39Å; T474-L478 WeakPolarHBondContact O-CB 3.19Å; T474-L478 WeakPolarHBondContact O-CD1 3.22Å; T474-L478 WeakPolarHBondContact O-CG 3.35Å; T474-L478 PolarHBondContact O-N 3.31Å
475	F	59.6	Low	50.2	Low	118 Å²	118	93 Å²	93	52%	0.518	46%	0.461	S	S	.	.	H	α-helix	trans	-67.4	-41.1	170.6	-89.1	-71	0	0	0	111.1	L471 D477 L478 I479	L471-F475 HydrophobicContact CB-CD2 4.46Å; L471-F475 HydrophobicContact CD2-CE2 4.47Å; L471-F475 WeakPolarHBondContact O-CA 3.48Å; L471-F475 WeakPolarHBondContact O-CB 3.45Å; L471-F475 WeakPolarHBondContact O-CD2 3Å; L471-F475 PolarHBondContact O-N 2.75Å; F475-D477 VanDerWaalsContact C-N 3.29Å; F475-D477 PolarHBondContact O-N 3.05Å; F475-L478 PolarHBondContact O-N 3.48Å; F475-I479 WeakPolarHBondContact O-CB 3.11Å; F475-I479 VanDerWaalsContact O-CD1 3.28Å; F475-I479 WeakPolarHBondContact O-CD1 3.3Å; F475-I479 WeakPolarHBondContact O-CG1 3.26Å; F475-I479 PolarHBondContact O-N 3.23Å
476	S	56.9	Low	49.8	Very low	41 Å²	41	99.9 Å²	99.9	29%	0.287	48%	0.48	S	S	.	.	H	α-helix	trans	-70.1	-28.9	176	77.6	0	0	0	0	112.1	M472 Y473 S480	M472-S476 WeakPolarHBondContact O-CA 3.05Å; M472-S476 WeakPolarHBondContact O-CB 3.48Å; M472-S476 PolarHBondContact O-N 3.32Å; M472-S476 PolarHBondContact O-OG 3.06Å; Y473-S476 WeakPolarHBondContact CA-OG 3.1Å; Y473-S476 CarbonylContact O-C 3.52Å; Y473-S476 PolarHBondContact O-N 2.96Å; Y473-S476 PolarHBondContact O-OG 2.76Å; S476-S480 WeakPolarHBondContact O-CA 3.47Å; S476-S480 WeakPolarHBondContact O-CB 2.99Å; S476-S480 PolarHBondContact O-N 3.46Å; S476-S480 PolarHBondContact O-OG 2.73Å
477	D	55	Low	49.9	Very low	83 Å²	83	100.4 Å²	100.4	44%	0.444	48%	0.477	S	S	.	.	H	α-helix	trans	-77.2	-40.3	175.2	-71.3	-15.3	0	0	0	109.7	Y473 T474 F475 S480 F481	Y473-D477 WeakPolarHBondContact O-CA 3.32Å; Y473-D477 WeakPolarHBondContact O-CB 3.27Å; Y473-D477 PolarHBondContact O-N 2.77Å; T474-D477 PolarHBondContact O-N 3.39Å; F475-D477 VanDerWaalsContact C-N 3.29Å; F475-D477 PolarHBondContact O-N 3.05Å; D477-S480 VanDerWaalsContact CA-OG 3.3Å; D477-S480 WeakPolarHBondContact CA-OG 3.2Å; D477-S480 CarbonylContact O-C 3.59Å; D477-S480 PolarHBondContact O-N 2.66Å; D477-S480 PolarHBondContact O-OG 2.76Å; D477-F481 WeakPolarHBondContact O-CB 3.26Å; D477-F481 VanDerWaalsContact O-CD2 3.22Å; D477-F481 WeakPolarHBondContact O-CD2 3.47Å; D477-F481 PolarHBondContact O-N 3.45Å
478	L	55.8	Low	50	Low	108 Å²	108	100.3 Å²	100.3	57%	0.565	47%	0.474	S	S	*	.	H	α-helix	trans	-64.6	-42.5	171.2	-75.3	164.7	0	0	0	111.1	T474 F475 F481 V482	T474-L478 WeakPolarHBondContact O-CB 3.19Å; T474-L478 WeakPolarHBondContact O-CD1 3.22Å; T474-L478 WeakPolarHBondContact O-CG 3.35Å; T474-L478 PolarHBondContact O-N 3.31Å; F475-L478 PolarHBondContact O-N 3.48Å; L478-F481 PolarHBondContact O-N 2.81Å; L478-V482 VanDerWaalsContact O-CG2 3.28Å; L478-V482 WeakPolarHBondContact O-CG2 3.03Å; L478-V482 PolarHBondContact O-N 2.91Å; L478-V482 VanDerWaalsContact O-N 3.09Å
479	I	51.8	Low	50	Low	44 Å²	44	98.7 Å²	98.7	23%	0.226	47%	0.469	C	S	.	.	H	α-helix	trans	-70.2	-38.9	175.4	-68	161.5	0	0	0	109.9	I236 F475 V482 V483	I236-I479 HydrophobicContact CD1-CD1 4.43Å; I236-I479 HydrophobicContact CG2-CD1 4.2Å; F475-I479 WeakPolarHBondContact O-CB 3.11Å; F475-I479 VanDerWaalsContact O-CD1 3.28Å; F475-I479 WeakPolarHBondContact O-CD1 3.3Å; F475-I479 WeakPolarHBondContact O-CG1 3.26Å; F475-I479 PolarHBondContact O-N 3.23Å; I479-V482 CarbonylContact O-C 3.59Å; I479-V482 PolarHBondContact O-N 2.77Å; I479-V482 VanDerWaalsContact O-N 3.13Å; I479-V483 HydrophobicContact CG2-CG2 3.9Å; I479-V483 VanDerWaalsContact O-CB 3.25Å; I479-V483 WeakPolarHBondContact O-CB 3.47Å; I479-V483 WeakPolarHBondContact O-CG2 2.99Å; I479-V483 PolarHBondContact O-N 3.31Å
480	S	46.8	Very low	50	Low	43 Å²	43	98.7 Å²	98.7	30%	0.301	47%	0.471	S	S	.	.	H	α-helix	trans	-67.6	-37.2	174.1	75	0	0	0	0	110.3	S476 D477 V482 V483 F484	S476-S480 WeakPolarHBondContact O-CA 3.47Å; S476-S480 WeakPolarHBondContact O-CB 2.99Å; S476-S480 PolarHBondContact O-N 3.46Å; S476-S480 PolarHBondContact O-OG 2.73Å; D477-S480 VanDerWaalsContact CA-OG 3.3Å; D477-S480 WeakPolarHBondContact CA-OG 3.2Å; D477-S480 CarbonylContact O-C 3.59Å; D477-S480 PolarHBondContact O-N 2.66Å; D477-S480 PolarHBondContact O-OG 2.76Å; S480-V482 PolarHBondContact O-N 3.45Å; S480-V483 CarbonylContact O-C 3.59Å; S480-V483 PolarHBondContact O-N 2.7Å; S480-V483 VanDerWaalsContact O-N 3.12Å; S480-F484 WeakPolarHBondContact O-CA 3.42Å; S480-F484 WeakPolarHBondContact O-CB 3.03Å; S480-F484 PolarHBondContact O-N 3.22Å
481	F	45.3	Very low	49.7	Very low	169 Å²	169	103.1 Å²	103.1	74%	0.741	48%	0.482	S	S	*	.	H	α-helix	trans	-59.6	-32.5	169.8	-96.9	-77	0	0	0	112.9	D477 L478	D477-F481 WeakPolarHBondContact O-CB 3.26Å; D477-F481 VanDerWaalsContact O-CD2 3.22Å; D477-F481 WeakPolarHBondContact O-CD2 3.47Å; D477-F481 PolarHBondContact O-N 3.45Å; L478-F481 PolarHBondContact O-N 2.81Å
482	V	44.2	Very low	49.3	Very low	73 Å²	73	104.8 Å²	104.8	44%	0.442	49%	0.487	S	S	.	.	H	α-helix	trans	-79.5	-32.6	175.2	173.1	0	0	0	0	112.3	P174 L478 I479 S480	P174-V482 HydrophobicContact CB-CG1 4.5Å; L478-V482 VanDerWaalsContact O-CG2 3.28Å; L478-V482 WeakPolarHBondContact O-CG2 3.03Å; L478-V482 PolarHBondContact O-N 2.91Å; L478-V482 VanDerWaalsContact O-N 3.09Å; I479-V482 CarbonylContact O-C 3.59Å; I479-V482 PolarHBondContact O-N 2.77Å; I479-V482 VanDerWaalsContact O-N 3.13Å; S480-V482 PolarHBondContact O-N 3.45Å
483	V	44.3	Very low	48.6	Very low	35 Å²	35	110 Å²	110	21%	0.212	51%	0.511	C	S	.	.	H	α-helix	trans	-96.9	-24.9	-173.5	173.9	0	0	0	0	113.2	I479 S480 R485	I479-V483 HydrophobicContact CG2-CG2 3.9Å; I479-V483 VanDerWaalsContact O-CB 3.25Å; I479-V483 WeakPolarHBondContact O-CB 3.47Å; I479-V483 WeakPolarHBondContact O-CG2 2.99Å; I479-V483 PolarHBondContact O-N 3.31Å; S480-V483 CarbonylContact O-C 3.59Å; S480-V483 PolarHBondContact O-N 2.7Å; S480-V483 VanDerWaalsContact O-N 3.12Å; V483-R485 VanDerWaalsContact C-N 3.34Å
484	F	36.7	Very low	47.8	Very low	165 Å²	165	107.2 Å²	107.2	72%	0.724	51%	0.506	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88	0.1	-179.1	-125.7	-87.8	0	0	0	113.2	S480	S480-F484 WeakPolarHBondContact O-CA 3.42Å; S480-F484 WeakPolarHBondContact O-CB 3.03Å; S480-F484 PolarHBondContact O-N 3.22Å
485	R	33.5	Very low	47.1	Very low	229 Å²	229	110.2 Å²	110.2	86%	0.864	51%	0.511	S	S	*	.	T	Hydrogen-bonded Turn	trans	-102.5	9.4	170.4	-149.9	178.3	162.1	179.4	-5.2	112.8	V483	V483-R485 VanDerWaalsContact C-N 3.34Å
486	W	34.9	Very low	45.9	Very low	214 Å²	214	109.5 Å²	109.5	81%	0.811	51%	0.511	S	S	*	.			trans	-119.3	0	169.9	-75.9	93.2	0	0	0	110.7	F136	F136-W486 HydrophobicContact CD2-CZ3 4.24Å; F136-W486 HydrophobicContact CE2-CH2 4.05Å; F136-W486 AromaticContact CE2-CZ3 3.68Å; F136-W486 HydrophobicContact CE2-CZ3 3.68Å; F136-W486 HydrophobicContact CZ-CH2 4.13Å; F136-W486 HydrophobicContact CZ-CZ3 4.13Å

Retrieved 486 of 486 residues in 356.1 ms (Link to these results)

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