A0A5K4EGD2_SCHMA Loading...

Peroxiredoxin, Prx4

AlphaFold DB , UniProt , Accession A0A5K4EGD2, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 621 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	47	Very low	50.3	Low	121 Å²	121	94.7 Å²	94.7	60%	0.596	50%	0.5	S	S	*	.				0	120.9	0	-151.2	173.1	-177.1	0	0	107.5	E5 I6 L9	M1-E5 VanDerWaalsContact C-OE2 3.31Å; M1-E5 WeakPolarHBondContact CA-OE2 3.47Å; M1-E5 HydrophobicContact CE-CB 3.96Å; M1-E5 HydrophobicContact CG-CB 3.69Å; M1-E5 HydrophobicContact CG-CG 4.49Å; M1-E5 WeakPolarHBondContact CG-OE2 3.27Å; M1-I6 HydrophobicContact CG-CG1 4.32Å; M1-I6 HydrophobicContact SD-CG1 4.19Å; M1-L9 HydrophobicContact CE-CD1 3.91Å
2	T	54.9	Low	50.8	Low	77 Å²	77	94.4 Å²	94.4	47%	0.472	50%	0.498	S	S	.	.			trans	-76.9	159.8	-178.1	59.4	0	0	0	0	110.7	D4 E5 I6	T2-D4 PolarHBondContact O-N 2.8Å; T2-E5 PolarHBondContact N-OE2 2.97Å; T2-E5 PolarHBondContact O-N 3.41Å; T2-E5 VanDerWaalsContact O-N 3.08Å; T2-E5 WeakPolarHBondContact OG1-CG 3.41Å; T2-E5 PolarHBondContact OG1-N 3.23Å; T2-I6 PolarHBondContact O-N 3.42Å
3	K	44.2	Very low	50.6	Low	178 Å²	178	92.8 Å²	92.8	77%	0.774	49%	0.485	S	S	*	.	H	α-helix	trans	-55.4	-31.5	174.9	-163	179.8	-177.8	-176.5	0	111.7	S7	K3-S7 WeakPolarHBondContact O-CB 3.45Å; K3-S7 PolarHBondContact O-N 2.62Å; K3-S7 VanDerWaalsContact O-N 3.08Å; K3-S7 PolarHBondContact O-OG 2.95Å
4	D	50.9	Low	50.1	Low	124 Å²	124	91.7 Å²	91.7	66%	0.663	49%	0.489	S	S	*	.	H	α-helix	trans	-70.9	-40.2	177.2	-59.9	-34.2	0	0	0	112.2	T2 I6 S7 L8	T2-D4 PolarHBondContact O-N 2.8Å; D4-I6 VanDerWaalsContact C-N 3.35Å; D4-I6 PolarHBondContact O-N 2.97Å; D4-S7 PolarHBondContact O-N 3.2Å; D4-L8 WeakPolarHBondContact O-CB 3.44Å; D4-L8 PolarHBondContact O-N 3.3Å
5	E	51.5	Low	49.8	Very low	97 Å²	97	99.7 Å²	99.7	45%	0.453	51%	0.51	S	S	.	.	H	α-helix	trans	-64.4	-38.6	176.2	-75.1	171.8	154.1	0	0	112.2	M1 T2 L9	M1-E5 VanDerWaalsContact C-OE2 3.31Å; M1-E5 WeakPolarHBondContact CA-OE2 3.47Å; M1-E5 HydrophobicContact CE-CB 3.96Å; M1-E5 HydrophobicContact CG-CB 3.69Å; M1-E5 HydrophobicContact CG-CG 4.49Å; M1-E5 WeakPolarHBondContact CG-OE2 3.27Å; T2-E5 PolarHBondContact N-OE2 2.97Å; T2-E5 PolarHBondContact O-N 3.41Å; T2-E5 VanDerWaalsContact O-N 3.08Å; T2-E5 WeakPolarHBondContact OG1-CG 3.41Å; T2-E5 PolarHBondContact OG1-N 3.23Å; E5-L9 WeakPolarHBondContact O-CB 3.43Å; E5-L9 PolarHBondContact O-N 3.03Å
6	I	47.6	Very low	49.5	Very low	79 Å²	79	98.8 Å²	98.8	41%	0.405	52%	0.515	S	S	.	.	H	α-helix	trans	-66.3	-43	175.3	-64	172.5	0	0	0	110.2	M1 T2 D4 L9 I10	M1-I6 HydrophobicContact CG-CG1 4.32Å; M1-I6 HydrophobicContact SD-CG1 4.19Å; T2-I6 PolarHBondContact O-N 3.42Å; D4-I6 VanDerWaalsContact C-N 3.35Å; D4-I6 PolarHBondContact O-N 2.97Å; I6-L9 PolarHBondContact O-N 3.32Å; I6-I10 HydrophobicContact CG2-CD1 3.83Å; I6-I10 VanDerWaalsContact O-CG1 3.24Å; I6-I10 WeakPolarHBondContact O-CG1 3.1Å; I6-I10 PolarHBondContact O-N 3.04Å
7	S	47.4	Very low	49	Very low	64 Å²	64	96.6 Å²	96.6	45%	0.448	51%	0.507	S	S	.	.	H	α-helix	trans	-65.5	-39.3	178.2	-56.8	0	0	0	0	112	K3 D4 I10 A11	K3-S7 WeakPolarHBondContact O-CB 3.45Å; K3-S7 PolarHBondContact O-N 2.62Å; K3-S7 VanDerWaalsContact O-N 3.08Å; K3-S7 PolarHBondContact O-OG 2.95Å; D4-S7 PolarHBondContact O-N 3.2Å; S7-I10 PolarHBondContact O-N 3.31Å; S7-A11 VanDerWaalsContact O-CB 3.27Å; S7-A11 WeakPolarHBondContact O-CB 3.49Å; S7-A11 PolarHBondContact O-N 3.34Å
8	L	56.6	Low	48.4	Very low	116 Å²	116	97.7 Å²	97.7	61%	0.607	52%	0.518	S	S	*	.	H	α-helix	trans	-67.5	-37.2	176.2	-150.1	91.1	0	0	0	111.7	D4 A11 N12	D4-L8 WeakPolarHBondContact O-CB 3.44Å; D4-L8 PolarHBondContact O-N 3.3Å; L8-A11 PolarHBondContact O-N 2.88Å; L8-N12 VanDerWaalsContact O-CB 3.32Å; L8-N12 WeakPolarHBondContact O-CB 3.01Å; L8-N12 PolarHBondContact O-N 3.49Å; L8-N12 PolarHBondContact O-ND2 3.33Å
9	L	51.8	Low	47.7	Very low	56 Å²	56	99.5 Å²	99.5	29%	0.293	54%	0.536	S	S	.	.	H	α-helix	trans	-68.4	-43	177.2	-143.7	113.2	0	0	0	111.2	M1 E5 I6 F13 I33	M1-L9 HydrophobicContact CE-CD1 3.91Å; E5-L9 WeakPolarHBondContact O-CB 3.43Å; E5-L9 PolarHBondContact O-N 3.03Å; I6-L9 PolarHBondContact O-N 3.32Å; L9-F13 HydrophobicContact CD2-CD2 4.37Å; L9-F13 HydrophobicContact CD2-CE2 4.43Å; L9-F13 HydrophobicContact CG-CD2 4.46Å; L9-F13 WeakPolarHBondContact O-CB 3.48Å; L9-F13 WeakPolarHBondContact O-CD2 3.15Å; L9-F13 PolarHBondContact O-N 3.35Å; L9-I33 HydrophobicContact CD2-CD1 3.88Å
10	I	50.2	Low	47.5	Very low	93 Å²	93	98.4 Å²	98.4	48%	0.477	55%	0.549	S	S	.	.	H	α-helix	trans	-62.1	-44.2	174.2	-68	166.8	0	0	0	110.4	I6 S7 F13 S14	I6-I10 HydrophobicContact CG2-CD1 3.83Å; I6-I10 VanDerWaalsContact O-CG1 3.24Å; I6-I10 WeakPolarHBondContact O-CG1 3.1Å; I6-I10 PolarHBondContact O-N 3.04Å; S7-I10 PolarHBondContact O-N 3.31Å; I10-F13 PolarHBondContact O-N 3.44Å; I10-S14 WeakPolarHBondContact O-CB 3.05Å; I10-S14 PolarHBondContact O-N 2.93Å; I10-S14 PolarHBondContact O-OG 2.89Å
11	A	51.4	Low	47.5	Very low	37 Å²	37	98.6 Å²	98.6	31%	0.306	56%	0.557	S	S	.	*	H	α-helix	trans	-69.7	-35.7	-179.6	0	0	0	0	0	114	S7 L8 S14 R15	S7-A11 VanDerWaalsContact O-CB 3.27Å; S7-A11 WeakPolarHBondContact O-CB 3.49Å; S7-A11 PolarHBondContact O-N 3.34Å; L8-A11 PolarHBondContact O-N 2.88Å; A11-S14 PolarHBondContact O-OG 3.41Å; A11-R15 WeakPolarHBondContact O-CG 3.44Å; A11-R15 PolarHBondContact O-N 3.01Å
12	N	55.8	Low	47.4	Very low	91 Å²	91	95 Å²	95	49%	0.487	54%	0.542	S	S	.	.	H	α-helix	trans	-73.7	-33.9	176.2	-78.9	-23.5	0	0	0	112	L8 S16	L8-N12 VanDerWaalsContact O-CB 3.32Å; L8-N12 WeakPolarHBondContact O-CB 3.01Å; L8-N12 PolarHBondContact O-N 3.49Å; L8-N12 PolarHBondContact O-ND2 3.33Å; N12-S16 PolarHBondContact O-OG 3.2Å; N12-S16 VanDerWaalsContact O-OG 3.09Å
13	F	48	Very low	47	Very low	73 Å²	73	99.9 Å²	99.9	32%	0.32	55%	0.553	S	S	.	*	H	α-helix	trans	-77.3	-30.2	174.2	-92.9	-85.5	0	0	0	112.8	L9 I10 R15 S16 V17 M26 K29	L9-F13 HydrophobicContact CD2-CD2 4.37Å; L9-F13 HydrophobicContact CD2-CE2 4.43Å; L9-F13 HydrophobicContact CG-CD2 4.46Å; L9-F13 WeakPolarHBondContact O-CB 3.48Å; L9-F13 WeakPolarHBondContact O-CD2 3.15Å; L9-F13 PolarHBondContact O-N 3.35Å; I10-F13 PolarHBondContact O-N 3.44Å; F13-R15 VanDerWaalsContact C-N 3.26Å; F13-R15 PolarHBondContact O-N 3.49Å; F13-S16 PolarHBondContact O-N 3.18Å; F13-S16 PolarHBondContact O-OG 3.06Å; F13-V17 WeakPolarHBondContact O-CG2 3.3Å; F13-M26 HydrophobicContact CB-CE 3.81Å; F13-K29 HydrophobicContact CE1-CD 4.3Å; F13-K29 HydrophobicContact CZ-CD 4.17Å
14	S	44	Very low	47.1	Very low	78 Å²	78	98.3 Å²	98.3	55%	0.545	55%	0.548	S	S	.	.	H	α-helix	trans	-69.3	-24.1	176.1	72	0	0	0	0	113.2	I10 A11	I10-S14 WeakPolarHBondContact O-CB 3.05Å; I10-S14 PolarHBondContact O-N 2.93Å; I10-S14 PolarHBondContact O-OG 2.89Å; A11-S14 PolarHBondContact O-OG 3.41Å
15	R	46.5	Very low	47	Very low	211 Å²	211	95.1 Å²	95.1	80%	0.796	54%	0.539	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.2	-13.4	178.8	-73.7	178.8	-175.1	171.8	2.2	114.6	A11 F13	A11-R15 WeakPolarHBondContact O-CG 3.44Å; A11-R15 PolarHBondContact O-N 3.01Å; F13-R15 VanDerWaalsContact C-N 3.26Å; F13-R15 PolarHBondContact O-N 3.49Å
16	S	44.5	Very low	46.8	Very low	86 Å²	86	94 Å²	94	60%	0.601	53%	0.534	S	S	*	.	S	Bend	trans	-106.7	8.7	-170.1	45.7	0	0	0	0	114.5	N12 F13	N12-S16 PolarHBondContact O-OG 3.2Å; N12-S16 VanDerWaalsContact O-OG 3.09Å; F13-S16 PolarHBondContact O-N 3.18Å; F13-S16 PolarHBondContact O-OG 3.06Å
17	V	41.2	Very low	46.9	Very low	61 Å²	61	94.3 Å²	94.3	37%	0.37	54%	0.536	S	S	.	.			trans	-128.5	109.9	-158.5	179.6	0	0	0	0	112.6	F13 T22	F13-V17 WeakPolarHBondContact O-CG2 3.3Å; V17-T22 HydrophobicContact CG1-CG2 3.26Å; V17-T22 WeakPolarHBondContact CG1-OG1 3.41Å
18	T	38.6	Very low	47.1	Very low	116 Å²	116	94.1 Å²	94.1	71%	0.712	53%	0.532	S	S	*	.			trans	-67.4	151.6	167.9	30.8	0	0	0	0	111.7	G20	T18-G20 PolarHBondContact O-N 3.34Å
19	P	35.3	Very low	46.9	Very low	133 Å²	133	93.9 Å²	93.9	86%	0.864	53%	0.527	S	S	*	.	S	Bend	trans	-75.8	125.6	-177.3	2.5	12.9	0	0	0	110.9
20	G	42.7	Very low	46.8	Very low	77 Å²	77	95.2 Å²	95.2	79%	0.794	53%	0.534	S	S	*	.	S	Bend	trans	157.1	-26.4	163.7	0	0	0	0	0	119	T18	T18-G20 PolarHBondContact O-N 3.34Å
21	S	47.1	Very low	46.8	Very low	102 Å²	102	95.8 Å²	95.8	71%	0.713	54%	0.538	S	S	*	.	S	Bend	trans	-143.5	14.6	-171.7	60.6	0	0	0	0	114.8
22	T	46.2	Very low	46.9	Very low	45 Å²	45	99.7 Å²	99.7	28%	0.276	55%	0.549	S	S	.	.	H	α-helix	trans	-111.6	-17.6	-144.3	41.6	0	0	0	0	115.4	V17 M26	V17-T22 HydrophobicContact CG1-CG2 3.26Å; V17-T22 WeakPolarHBondContact CG1-OG1 3.41Å; T22-M26 WeakPolarHBondContact O-CB 3.44Å; T22-M26 PolarHBondContact O-N 3.29Å
23	Y	45.3	Very low	46.7	Very low	181 Å²	181	98.2 Å²	98.2	71%	0.71	54%	0.541	S	S	*	.	H	α-helix	trans	-69.6	-41.5	178.2	-160.5	-99.3	0	0	0	112.6	M26 L27	Y23-M26 PolarHBondContact O-N 2.8Å; Y23-L27 HydrophobicContact CD1-CD1 3.69Å; Y23-L27 HydrophobicContact CD1-CG 4.46Å; Y23-L27 HydrophobicContact CE1-CD1 3.55Å; Y23-L27 HydrophobicContact CE1-CG 4.31Å; Y23-L27 PolarHBondContact O-N 3.09Å
24	H	46.8	Very low	46.7	Very low	145 Å²	145	99.1 Å²	99.1	67%	0.671	55%	0.549	S	S	*	.	H	α-helix	trans	-66.8	-43.3	176.7	-170.1	72	0	0	0	111.5	M26 L27 V28	H24-M26 VanDerWaalsContact C-N 3.33Å; H24-M26 PolarHBondContact O-N 3.33Å; H24-L27 PolarHBondContact O-N 2.64Å; H24-V28 VanDerWaalsContact O-CG2 3.26Å; H24-V28 WeakPolarHBondContact O-CG2 3.19Å; H24-V28 PolarHBondContact O-N 3.48Å
25	A	49.1	Very low	46.9	Very low	56 Å²	56	98.7 Å²	98.7	46%	0.463	54%	0.543	S	S	.	.	H	α-helix	trans	-62.7	-38.5	175.8	0	0	0	0	0	112.3	K29	A25-K29 WeakPolarHBondContact O-CB 3.47Å; A25-K29 PolarHBondContact O-N 3.49Å
26	M	47.5	Very low	47.1	Very low	74 Å²	74	95.4 Å²	95.4	37%	0.365	53%	0.534	S	S	.	.	H	α-helix	trans	-61.4	-49.6	172.8	-103.3	-175.9	151.9	0	0	112	F13 T22 Y23 H24 V28 K29 L30	F13-M26 HydrophobicContact CB-CE 3.81Å; T22-M26 WeakPolarHBondContact O-CB 3.44Å; T22-M26 PolarHBondContact O-N 3.29Å; Y23-M26 PolarHBondContact O-N 2.8Å; H24-M26 VanDerWaalsContact C-N 3.33Å; H24-M26 PolarHBondContact O-N 3.33Å; M26-V28 VanDerWaalsContact C-N 3.33Å; M26-V28 PolarHBondContact O-N 3.48Å; M26-K29 PolarHBondContact O-N 3.33Å; M26-L30 WeakPolarHBondContact O-CB 3.29Å; M26-L30 PolarHBondContact O-N 3Å
27	L	49.6	Very low	47.3	Very low	85 Å²	85	94.8 Å²	94.8	45%	0.445	52%	0.524	S	S	.	.	H	α-helix	trans	-60.9	-41.4	178.7	-82.8	165.9	0	0	0	112.1	Y23 H24 N31	Y23-L27 HydrophobicContact CD1-CD1 3.69Å; Y23-L27 HydrophobicContact CD1-CG 4.46Å; Y23-L27 HydrophobicContact CE1-CD1 3.55Å; Y23-L27 HydrophobicContact CE1-CG 4.31Å; Y23-L27 PolarHBondContact O-N 3.09Å; H24-L27 PolarHBondContact O-N 2.64Å; L27-N31 WeakPolarHBondContact O-CB 3.14Å; L27-N31 PolarHBondContact O-N 3.43Å
28	V	51.4	Low	47.6	Very low	60 Å²	60	95.9 Å²	95.9	36%	0.364	53%	0.527	S	S	.	.	H	α-helix	trans	-63.5	-46.9	177.1	171	0	0	0	0	111.2	H24 M26 N31 Q32	H24-V28 VanDerWaalsContact O-CG2 3.26Å; H24-V28 WeakPolarHBondContact O-CG2 3.19Å; H24-V28 PolarHBondContact O-N 3.48Å; M26-V28 VanDerWaalsContact C-N 3.33Å; M26-V28 PolarHBondContact O-N 3.48Å; V28-N31 PolarHBondContact O-N 3.47Å; V28-Q32 WeakPolarHBondContact O-CG 3.21Å; V28-Q32 PolarHBondContact O-N 3.21Å
29	K	52.1	Low	48	Very low	112 Å²	112	97 Å²	97	49%	0.487	52%	0.52	S	S	.	.	H	α-helix	trans	-68.2	-38.5	-179.7	-120.3	159.5	179.6	171.8	0	112.4	F13 A25 M26 Q32 I33	F13-K29 HydrophobicContact CE1-CD 4.3Å; F13-K29 HydrophobicContact CZ-CD 4.17Å; A25-K29 WeakPolarHBondContact O-CB 3.47Å; A25-K29 PolarHBondContact O-N 3.49Å; M26-K29 PolarHBondContact O-N 3.33Å; K29-Q32 PolarHBondContact O-N 3.39Å; K29-I33 WeakPolarHBondContact O-CG1 3.47Å; K29-I33 PolarHBondContact O-N 3.45Å; K29-I33 VanDerWaalsContact O-N 3.08Å
30	L	50.3	Low	48.6	Very low	84 Å²	84	94.2 Å²	94.2	44%	0.44	50%	0.497	S	S	.	.	H	α-helix	trans	-63	-45.2	174.7	-158.8	88	0	0	0	110.9	M26 Q32 I33 L34	M26-L30 WeakPolarHBondContact O-CB 3.29Å; M26-L30 PolarHBondContact O-N 3Å; L30-Q32 VanDerWaalsContact C-N 3.35Å; L30-Q32 PolarHBondContact O-N 3.37Å; L30-I33 PolarHBondContact O-N 2.97Å; L30-L34 HydrophobicContact CD2-CD1 4.32Å; L30-L34 HydrophobicContact CG-CD1 4.23Å; L30-L34 WeakPolarHBondContact O-CB 3.05Å; L30-L34 WeakPolarHBondContact O-CG 3.32Å; L30-L34 PolarHBondContact O-N 3.25Å
31	N	49.2	Very low	48.8	Very low	105 Å²	105	94.2 Å²	94.2	56%	0.561	49%	0.485	S	S	*	.	H	α-helix	trans	-60.8	-41.2	175.2	-106.2	-21	0	0	0	112.4	L27 V28 T35	L27-N31 WeakPolarHBondContact O-CB 3.14Å; L27-N31 PolarHBondContact O-N 3.43Å; V28-N31 PolarHBondContact O-N 3.47Å; N31-T35 VanDerWaalsContact O-CB 3.32Å; N31-T35 WeakPolarHBondContact O-CB 3.29Å; N31-T35 PolarHBondContact O-N 2.95Å; N31-T35 PolarHBondContact O-OG1 2.9Å
32	Q	53.6	Low	48.8	Very low	118 Å²	118	93 Å²	93	55%	0.551	47%	0.473	S	S	*	.	H	α-helix	trans	-62.3	-45.3	177.2	-76	173.6	-6.7	0	0	112.4	V28 K29 L30 T35 K36	V28-Q32 WeakPolarHBondContact O-CG 3.21Å; V28-Q32 PolarHBondContact O-N 3.21Å; K29-Q32 PolarHBondContact O-N 3.39Å; L30-Q32 VanDerWaalsContact C-N 3.35Å; L30-Q32 PolarHBondContact O-N 3.37Å; Q32-T35 PolarHBondContact O-N 3.32Å; Q32-K36 WeakPolarHBondContact O-CB 3.14Å; Q32-K36 PolarHBondContact O-N 3.41Å
33	I	52.5	Low	48.8	Very low	60 Å²	60	95 Å²	95	31%	0.308	48%	0.48	S	S	.	.	H	α-helix	trans	-66	-44.4	-179.4	-67.6	167.5	0	0	0	110.8	L9 K29 L30 K36 N37	L9-I33 HydrophobicContact CD2-CD1 3.88Å; K29-I33 WeakPolarHBondContact O-CG1 3.47Å; K29-I33 PolarHBondContact O-N 3.45Å; K29-I33 VanDerWaalsContact O-N 3.08Å; L30-I33 PolarHBondContact O-N 2.97Å; I33-K36 PolarHBondContact O-N 3.26Å; I33-N37 PolarHBondContact O-N 3.46Å; I33-N37 VanDerWaalsContact O-N 3.12Å; I33-N37 PolarHBondContact O-ND2 2.81Å
34	L	48.2	Very low	48.8	Very low	93 Å²	93	92 Å²	92	49%	0.487	47%	0.472	S	S	.	.	H	α-helix	trans	-63.1	-44.5	177.6	-72.6	167.9	0	0	0	111.6	L30 K36 N37 L38	L30-L34 HydrophobicContact CD2-CD1 4.32Å; L30-L34 HydrophobicContact CG-CD1 4.23Å; L30-L34 WeakPolarHBondContact O-CB 3.05Å; L30-L34 WeakPolarHBondContact O-CG 3.32Å; L30-L34 PolarHBondContact O-N 3.25Å; L34-K36 PolarHBondContact O-N 3.5Å; L34-N37 PolarHBondContact O-N 3Å; L34-L38 WeakPolarHBondContact O-CB 3.41Å; L34-L38 PolarHBondContact O-N 2.93Å
35	T	47	Very low	48.7	Very low	68 Å²	68	93.4 Å²	93.4	42%	0.417	47%	0.472	S	S	.	.	H	α-helix	trans	-62.7	-43.1	178.7	-54.2	0	0	0	0	112	N31 Q32 L38 Y39	N31-T35 VanDerWaalsContact O-CB 3.32Å; N31-T35 WeakPolarHBondContact O-CB 3.29Å; N31-T35 PolarHBondContact O-N 2.95Å; N31-T35 PolarHBondContact O-OG1 2.9Å; Q32-T35 PolarHBondContact O-N 3.32Å; T35-L38 PolarHBondContact O-N 3.47Å; T35-Y39 PolarHBondContact O-N 3.18Å
36	K	50.9	Low	48.1	Very low	143 Å²	143	97.7 Å²	97.7	62%	0.622	48%	0.484	S	S	*	.	H	α-helix	trans	-65.9	-41.5	179.9	-173.1	173.7	-179.6	176.7	0	112.4	Q32 I33 L34 Y39 N40	Q32-K36 WeakPolarHBondContact O-CB 3.14Å; Q32-K36 PolarHBondContact O-N 3.41Å; I33-K36 PolarHBondContact O-N 3.26Å; L34-K36 PolarHBondContact O-N 3.5Å; K36-Y39 PolarHBondContact O-N 3.19Å; K36-N40 PolarHBondContact O-N 3.26Å
37	N	49.6	Very low	47.9	Very low	73 Å²	73	98.3 Å²	98.3	39%	0.39	49%	0.493	S	S	.	.	H	α-helix	trans	-69.1	-34.1	177.6	-79.1	-27.6	0	0	0	112.7	I33 L34 S41	I33-N37 PolarHBondContact O-N 3.46Å; I33-N37 VanDerWaalsContact O-N 3.12Å; I33-N37 PolarHBondContact O-ND2 2.81Å; L34-N37 PolarHBondContact O-N 3Å; N37-S41 WeakPolarHBondContact O-CB 3.41Å; N37-S41 PolarHBondContact O-N 3.27Å; N37-S41 PolarHBondContact O-OG 3.24Å
38	L	46.8	Very low	47.4	Very low	83 Å²	83	99.9 Å²	99.9	44%	0.435	50%	0.501	S	S	.	.	H	α-helix	trans	-66.8	-45.5	172.9	-113.8	133.1	0	0	0	111.7	L34 T35 S41 V42	L34-L38 WeakPolarHBondContact O-CB 3.41Å; L34-L38 PolarHBondContact O-N 2.93Å; T35-L38 PolarHBondContact O-N 3.47Å; L38-S41 PolarHBondContact O-N 3.07Å; L38-V42 WeakPolarHBondContact O-CG2 3.33Å; L38-V42 PolarHBondContact O-N 3.45Å
39	Y	47.7	Very low	46.8	Very low	140 Å²	140	104.4 Å²	104.4	55%	0.549	52%	0.516	S	S	.	.	H	α-helix	trans	-56.3	-52	174.6	178.5	-89.3	0	0	0	111.3	T35 K36 S41 V42 E43	T35-Y39 PolarHBondContact O-N 3.18Å; K36-Y39 PolarHBondContact O-N 3.19Å; Y39-S41 VanDerWaalsContact C-N 3.29Å; Y39-S41 PolarHBondContact O-N 2.8Å; Y39-V42 PolarHBondContact O-N 3.4Å; Y39-E43 HydrophobicContact CE1-CB 4.35Å; Y39-E43 VanDerWaalsContact CE1-OE2 3.24Å; Y39-E43 WeakPolarHBondContact CE1-OE2 3.47Å; Y39-E43 WeakPolarHBondContact O-CB 3.27Å; Y39-E43 PolarHBondContact O-N 2.96Å; Y39-E43 PolarHBondContact OH-OE1 3.39Å
40	N	47.3	Very low	46	Very low	74 Å²	74	107 Å²	107	40%	0.396	53%	0.53	S	S	.	.	H	α-helix	trans	-60.7	-36.8	179.2	-71.2	-3.6	0	0	0	112.3	K36 H44	K36-N40 PolarHBondContact O-N 3.26Å; N40-H44 WeakPolarHBondContact O-CB 3.48Å; N40-H44 PolarHBondContact O-N 3.45Å
41	S	47.6	Very low	45.1	Very low	77 Å²	77	108.3 Å²	108.3	54%	0.538	54%	0.543	S	S	.	.	H	α-helix	trans	-68.9	-40.4	177.1	-67.1	0	0	0	0	112.5	N37 L38 Y39 Y45	N37-S41 WeakPolarHBondContact O-CB 3.41Å; N37-S41 PolarHBondContact O-N 3.27Å; N37-S41 PolarHBondContact O-OG 3.24Å; L38-S41 PolarHBondContact O-N 3.07Å; Y39-S41 VanDerWaalsContact C-N 3.29Å; Y39-S41 PolarHBondContact O-N 2.8Å; S41-Y45 WeakPolarHBondContact O-CB 3.33Å; S41-Y45 PolarHBondContact O-N 2.71Å
42	V	45.6	Very low	44.3	Very low	76 Å²	76	109.6 Å²	109.6	46%	0.461	56%	0.555	S	S	.	*	H	α-helix	trans	-69.2	-43.8	177.2	172.2	0	0	0	0	110.8	L38 Y39 H44 Y45 M46	L38-V42 WeakPolarHBondContact O-CG2 3.33Å; L38-V42 PolarHBondContact O-N 3.45Å; Y39-V42 PolarHBondContact O-N 3.4Å; V42-H44 VanDerWaalsContact C-N 3.35Å; V42-Y45 PolarHBondContact O-N 3.23Å; V42-M46 HydrophobicContact CG1-CG 4.24Å; V42-M46 WeakPolarHBondContact O-CB 3.41Å; V42-M46 WeakPolarHBondContact O-CG 3.43Å; V42-M46 PolarHBondContact O-N 3.44Å
43	E	46	Very low	43.3	Very low	88 Å²	88	109.4 Å²	109.4	41%	0.411	57%	0.566	S	S	.	*	H	α-helix	trans	-63.7	-40.7	177	-164.8	177.2	-133.9	0	0	111.2	Y39 M46 T47	Y39-E43 HydrophobicContact CE1-CB 4.35Å; Y39-E43 VanDerWaalsContact CE1-OE2 3.24Å; Y39-E43 WeakPolarHBondContact CE1-OE2 3.47Å; Y39-E43 WeakPolarHBondContact O-CB 3.27Å; Y39-E43 PolarHBondContact O-N 2.96Å; Y39-E43 PolarHBondContact OH-OE1 3.39Å; E43-M46 PolarHBondContact O-N 3.23Å; E43-T47 WeakPolarHBondContact O-CB 3.48Å; E43-T47 PolarHBondContact O-N 3.4Å; E43-T47 PolarHBondContact O-OG1 3.36Å
44	H	47	Very low	42.4	Very low	117 Å²	117	112.9 Å²	112.9	54%	0.542	59%	0.59	S	S	.	*	H	α-helix	trans	-62.6	-42.1	172.7	-166.7	65.9	0	0	0	112.1	N40 V42 M46 T47 L48	N40-H44 WeakPolarHBondContact O-CB 3.48Å; N40-H44 PolarHBondContact O-N 3.45Å; V42-H44 VanDerWaalsContact C-N 3.35Å; H44-M46 VanDerWaalsContact C-N 3.32Å; H44-M46 PolarHBondContact O-N 3.29Å; H44-T47 WeakPolarHBondContact CA-OG1 3.35Å; H44-T47 PolarHBondContact O-N 3.23Å; H44-T47 PolarHBondContact O-OG1 3.29Å; H44-L48 WeakPolarHBondContact NE2-CD1 3.27Å; H44-L48 WeakPolarHBondContact O-CB 3.37Å; H44-L48 WeakPolarHBondContact O-CD1 3.04Å; H44-L48 WeakPolarHBondContact O-CG 3.49Å; H44-L48 PolarHBondContact O-N 2.82Å; H44-L48 VanDerWaalsContact O-N 3.07Å
45	Y	42.6	Very low	41.7	Very low	175 Å²	175	113.7 Å²	113.7	69%	0.686	60%	0.601	S	S	*	*	H	α-helix	trans	-66.8	-31.7	175.8	-121.2	-89.7	0	0	0	113.3	S41 V42	S41-Y45 WeakPolarHBondContact O-CB 3.33Å; S41-Y45 PolarHBondContact O-N 2.71Å; V42-Y45 PolarHBondContact O-N 3.23Å
46	M	37.8	Very low	40.9	Very low	146 Å²	146	117.7 Å²	117.7	72%	0.719	62%	0.62	S	S	*	*	H	α-helix	trans	-80	-34.3	178.7	-68.8	-84.7	-97.1	0	0	112.2	V42 E43 H44	V42-M46 HydrophobicContact CG1-CG 4.24Å; V42-M46 WeakPolarHBondContact O-CB 3.41Å; V42-M46 WeakPolarHBondContact O-CG 3.43Å; V42-M46 PolarHBondContact O-N 3.44Å; E43-M46 PolarHBondContact O-N 3.23Å; H44-M46 VanDerWaalsContact C-N 3.32Å; H44-M46 PolarHBondContact O-N 3.29Å
47	T	43.9	Very low	40.1	Very low	88 Å²	88	117.8 Å²	117.8	54%	0.54	63%	0.626	S	S	.	*	H	α-helix	trans	-79.6	-28.6	178.7	42	0	0	0	0	113.2	E43 H44 K49	E43-T47 WeakPolarHBondContact O-CB 3.48Å; E43-T47 PolarHBondContact O-N 3.4Å; E43-T47 PolarHBondContact O-OG1 3.36Å; H44-T47 WeakPolarHBondContact CA-OG1 3.35Å; H44-T47 PolarHBondContact O-N 3.23Å; H44-T47 PolarHBondContact O-OG1 3.29Å; T47-K49 PolarHBondContact O-N 2.93Å
48	L	39	Very low	39.1	Very low	117 Å²	117	123.8 Å²	123.8	61%	0.613	65%	0.651	S	S	*	*	T	Hydrogen-bonded Turn	trans	-71.6	-3.9	177.5	-83.2	166.2	0	0	0	115.4	H44	H44-L48 WeakPolarHBondContact NE2-CD1 3.27Å; H44-L48 WeakPolarHBondContact O-CB 3.37Å; H44-L48 WeakPolarHBondContact O-CD1 3.04Å; H44-L48 WeakPolarHBondContact O-CG 3.49Å; H44-L48 PolarHBondContact O-N 2.82Å; H44-L48 VanDerWaalsContact O-N 3.07Å
49	K	38.5	Very low	38.4	Very low	156 Å²	156	125.2 Å²	125.2	68%	0.678	66%	0.664	S	S	*	*	T	Hydrogen-bonded Turn	trans	-121	29.5	-177.4	-71.4	-163	175.2	-171.5	0	115	T47	T47-K49 PolarHBondContact O-N 2.93Å
50	Q	33.8	Very low	37.6	Very low	166 Å²	166	128.2 Å²	128.2	78%	0.776	68%	0.683	S	S	*	*			trans	-67.9	126.7	159	-74.5	-159.8	-2.9	0	0	109.6	T52	Q50-T52 PolarHBondContact O-N 3.45Å
51	P	31.7	Very low	36.7	Very low	112 Å²	112	127.4 Å²	127.4	73%	0.727	69%	0.691	S	S	*	*			trans	-83.2	106.9	-168	31.2	-31.5	0	0	0	111.5
52	T	33.8	Very low	35.7	Very low	132 Å²	132	132.9 Å²	132.9	81%	0.81	71%	0.708	S	S	*	*			trans	-91.9	105.3	154.4	29.9	0	0	0	0	109.1	Q50	Q50-T52 PolarHBondContact O-N 3.45Å
53	S	31.4	Very low	35	Very low	113 Å²	113	133.6 Å²	133.6	79%	0.79	72%	0.722	S	S	*	*			trans	57.9	130.1	158.9	57	0	0	0	0	120.5
54	V	33.3	Very low	34.2	Very low	134 Å²	134	136.3 Å²	136.3	81%	0.812	73%	0.733	S	S	*	*			trans	-79.5	140.9	172.1	-176	0	0	0	0	109.3
55	P	35	Very low	33.7	Very low	110 Å²	110	135.5 Å²	135.5	71%	0.714	73%	0.732	S	S	*	*				-149.5	143.5	106.3	31.8	-11.3	0	0	0	117
56	N	30	Very low	33.5	Very low	152 Å²	152	138.6 Å²	138.6	81%	0.813	74%	0.743	S	S	*	*			trans	18.2	97.2	142.7	-64.3	-9.1	0	0	0	119.2
57	I	33.6	Very low	33.6	Very low	145 Å²	145	140.5 Å²	140.5	74%	0.744	75%	0.747	S	S	*	*			trans	-146.9	122.7	147.5	-59.6	-175.4	0	0	0	108.9	T59	I57-T59 HydrophobicContact CG2-CG2 4.3Å; I57-T59 PolarHBondContact O-N 3.09Å
58	E	29.4	Very low	33.4	Very low	198 Å²	198	142.3 Å²	142.3	93%	0.925	75%	0.749	S	S	*	*			trans	-57.1	111	165.9	-69.5	173.3	154.5	0	0	109.6
59	T	30.4	Very low	33.5	Very low	113 Å²	113	145.3 Å²	145.3	69%	0.693	75%	0.752	S	S	*	*			trans	-138.7	124	167	33.5	0	0	0	0	109.2	I57 G61	I57-T59 HydrophobicContact CG2-CG2 4.3Å; I57-T59 PolarHBondContact O-N 3.09Å; T59-G61 PolarHBondContact O-N 3.25Å
60	H	31.1	Very low	33.7	Very low	204 Å²	204	143.1 Å²	143.1	94%	0.944	75%	0.748	S	S	*	*	S	Bend	trans	-55.6	129.6	164.4	-79.1	-81.7	0	0	0	109.5
61	G	28.4	Very low	34.1	Very low	56 Å²	56	142.9 Å²	142.9	58%	0.577	75%	0.747	S	S	*	*	S	Bend	trans	108.2	140.5	173	0	0	0	0	0	113.1	T59	T59-G61 PolarHBondContact O-N 3.25Å
62	E	27.3	Very low	34.6	Very low	192 Å²	192	139.2 Å²	139.2	90%	0.897	73%	0.73	S	S	*	*			trans	83.5	131.8	163.1	-48.8	-172.7	166.4	0	0	117.6
63	A	30	Very low	35	Very low	91 Å²	91	140.1 Å²	140.1	75%	0.752	72%	0.72	S	S	*	*			trans	67	80	162.8	0	0	0	0	0	119
64	F	30.4	Very low	35.5	Very low	145 Å²	145	135.6 Å²	135.6	64%	0.636	69%	0.688	S	S	*	*			trans	-118.8	137.4	159.3	-140.8	-117.1	0	0	0	109.6	Q68	F64-Q68 VanDerWaalsContact CZ-OE1 3.31Å
65	L	36.3	Very low	36.1	Very low	100 Å²	100	134.6 Å²	134.6	52%	0.524	68%	0.678	S	S	.	*	S	Bend	trans	107.5	14.5	149.1	-56.3	174.5	0	0	0	124.5
66	W	38.5	Very low	36.5	Very low	241 Å²	241	139.6 Å²	139.6	91%	0.913	68%	0.683	S	S	*	*	S	Bend	trans	-103.5	-18.4	165.2	-63.6	89.9	0	0	0	114.4
67	K	39.4	Very low	37	Very low	185 Å²	185	139.7 Å²	139.7	80%	0.804	67%	0.673	S	S	*	*	S	Bend	trans	-97.6	-5.4	179.9	-75.7	-172.7	175.9	-178	0	114.9
68	Q	40.2	Very low	37.3	Very low	127 Å²	127	138.4 Å²	138.4	59%	0.593	66%	0.662	S	S	*	*	S	Bend	trans	-111.6	1.2	-180	-102.7	-177.2	-5.1	0	0	114	F64 D70	F64-Q68 VanDerWaalsContact CZ-OE1 3.31Å; Q68-D70 PolarHBondContact O-N 2.93Å
69	W	40.8	Very low	37.9	Very low	179 Å²	179	139.3 Å²	139.3	68%	0.678	66%	0.663	S	S	*	*			trans	-78.2	62.6	169.7	-143.7	-49.9	0	0	0	109.7
70	D	42.5	Very low	38.3	Very low	110 Å²	110	136.6 Å²	136.6	59%	0.588	64%	0.644	S	S	*	*			trans	-78.3	127.4	175.6	-155.4	-6.1	0	0	0	107.5	Q68 G72 Y73 S74	Q68-D70 PolarHBondContact O-N 2.93Å; D70-G72 PolarHBondContact O-N 3.34Å; D70-Y73 PolarHBondContact O-N 3.17Å; D70-S74 PolarHBondContact O-N 3.3Å
71	Q	42.9	Very low	38.8	Very low	161 Å²	161	131.3 Å²	131.3	75%	0.752	63%	0.626	S	S	*	*	H	α-helix	trans	-50.6	-33.5	176.3	-100.4	168.4	-36.1	0	0	110.9	Y73 S74 D75	Q71-Y73 VanDerWaalsContact C-N 3.35Å; Q71-Y73 PolarHBondContact O-N 3.04Å; Q71-S74 PolarHBondContact O-N 3.03Å; Q71-D75 WeakPolarHBondContact O-CB 3.42Å; Q71-D75 PolarHBondContact O-N 3.32Å; Q71-D75 VanDerWaalsContact O-N 3.08Å
72	G	41.9	Very low	39.4	Very low	36 Å²	36	134.3 Å²	134.3	37%	0.371	64%	0.636	S	S	.	*	H	α-helix	trans	-67.5	-22.3	176.3	0	0	0	0	0	116.1	D70 R76	D70-G72 PolarHBondContact O-N 3.34Å; G72-R76 WeakPolarHBondContact O-CG 3.4Å
73	Y	42	Very low	40.1	Very low	150 Å²	150	130.4 Å²	130.4	59%	0.588	63%	0.629	S	S	*	*	H	α-helix	trans	-85.2	-35.1	176.5	-139.7	-85.7	0	0	0	111.4	D70 Q71 Y77	D70-Y73 PolarHBondContact O-N 3.17Å; Q71-Y73 VanDerWaalsContact C-N 3.35Å; Q71-Y73 PolarHBondContact O-N 3.04Å; Y73-Y77 AromaticContact CD1-CD2 3.88Å; Y73-Y77 HydrophobicContact CD1-CD2 3.88Å; Y73-Y77 AromaticContact CD1-CE2 3.99Å; Y73-Y77 HydrophobicContact CD1-CE2 3.99Å; Y73-Y77 AromaticContact CE1-CD2 3.88Å; Y73-Y77 HydrophobicContact CE1-CD2 3.88Å; Y73-Y77 AromaticContact CE1-CE2 3.59Å; Y73-Y77 HydrophobicContact CE1-CE2 3.59Å; Y73-Y77 AromaticContact CZ-CE2 3.98Å; Y73-Y77 WeakPolarHBondContact O-CD2 3.44Å
74	S	42.6	Very low	40.7	Very low	19 Å²	19	129 Å²	129	13%	0.133	62%	0.617	C	S	.	*	H	α-helix	trans	-71	-41.1	175.6	-67.6	0	0	0	0	111.9	D70 Q71 R76 Y77 F78	D70-S74 PolarHBondContact O-N 3.3Å; Q71-S74 PolarHBondContact O-N 3.03Å; S74-R76 VanDerWaalsContact C-N 3.28Å; S74-R76 PolarHBondContact O-N 2.91Å; S74-Y77 PolarHBondContact O-N 3.19Å; S74-F78 PolarHBondContact O-N 3.41Å; S74-F78 VanDerWaalsContact O-O 3.13Å
75	D	46.5	Very low	41.4	Very low	112 Å²	112	126.2 Å²	126.2	60%	0.599	60%	0.603	S	S	*	*	H	α-helix	trans	-66.7	-26.2	178.3	-74.7	-15.5	0	0	0	113.6	Q71	Q71-D75 WeakPolarHBondContact O-CB 3.42Å; Q71-D75 PolarHBondContact O-N 3.32Å; Q71-D75 VanDerWaalsContact O-N 3.08Å
76	R	43.4	Very low	42.3	Very low	216 Å²	216	124.6 Å²	124.6	82%	0.815	60%	0.599	S	S	*	*	H	α-helix	trans	-79.8	-30.6	-179.8	-83	-176.9	-167.6	-174.3	5.4	114.4	G72 S74	G72-R76 WeakPolarHBondContact O-CG 3.4Å; S74-R76 VanDerWaalsContact C-N 3.28Å; S74-R76 PolarHBondContact O-N 2.91Å
77	Y	39.7	Very low	43.2	Very low	154 Å²	154	115.3 Å²	115.3	60%	0.604	57%	0.57	S	S	*	*	H	α-helix	trans	-110.8	-25.8	-172.2	-73.8	-79.9	0	0	0	113.6	Y73 S74	Y73-Y77 AromaticContact CD1-CD2 3.88Å; Y73-Y77 HydrophobicContact CD1-CD2 3.88Å; Y73-Y77 AromaticContact CD1-CE2 3.99Å; Y73-Y77 HydrophobicContact CD1-CE2 3.99Å; Y73-Y77 AromaticContact CE1-CD2 3.88Å; Y73-Y77 HydrophobicContact CE1-CD2 3.88Å; Y73-Y77 AromaticContact CE1-CE2 3.59Å; Y73-Y77 HydrophobicContact CE1-CE2 3.59Å; Y73-Y77 AromaticContact CZ-CE2 3.98Å; Y73-Y77 WeakPolarHBondContact O-CD2 3.44Å; S74-Y77 PolarHBondContact O-N 3.19Å
78	F	40	Very low	44.2	Very low	118 Å²	118	114.8 Å²	114.8	52%	0.518	57%	0.568	S	S	.	*			trans	-130.2	94.3	-174.1	-50.4	-83	0	0	0	107.7	S74 L80	S74-F78 PolarHBondContact O-N 3.41Å; S74-F78 VanDerWaalsContact O-O 3.13Å; F78-L80 HydrophobicContact CB-CD1 3.7Å; F78-L80 HydrophobicContact CB-CG 3.94Å; F78-L80 PolarHBondContact O-N 2.94Å
79	K	40.7	Very low	45.2	Very low	217 Å²	217	112.1 Å²	112.1	94%	0.943	56%	0.563	S	S	*	*			trans	-63.6	68.3	172.2	-70.9	-177.5	177.4	178.2	0	110.8
80	L	39.4	Very low	45.9	Very low	55 Å²	55	107.8 Å²	107.8	29%	0.288	55%	0.554	S	S	.	*			trans	-98.9	131.1	-179.5	-69.3	168.4	0	0	0	108.1	F78 Y85	F78-L80 HydrophobicContact CB-CD1 3.7Å; F78-L80 HydrophobicContact CB-CG 3.94Å; F78-L80 PolarHBondContact O-N 2.94Å; L80-Y85 HydrophobicContact CB-CE2 3.84Å; L80-Y85 HydrophobicContact CD1-CE1 4.5Å; L80-Y85 HydrophobicContact CD1-CE2 4.25Å; L80-Y85 WeakPolarHBondContact CD1-OH 3.44Å
81	T	42.1	Very low	46.8	Very low	94 Å²	94	106.7 Å²	106.7	58%	0.577	54%	0.544	S	S	*	.			trans	-61	138.5	170.5	31.9	0	0	0	0	109.9	S83 A84	T81-S83 PolarHBondContact O-N 3.46Å; T81-A84 WeakPolarHBondContact O-CB 3.27Å; T81-A84 PolarHBondContact O-N 2.94Å
82	P	41.8	Very low	47.7	Very low	119 Å²	119	102.8 Å²	102.8	77%	0.773	53%	0.527	S	S	*	.	G	3₁₀ helix	trans	-54.4	-23.3	-179.5	-27.7	33.9	0	0	0	115	A84	P82-A84 VanDerWaalsContact C-N 3.28Å; P82-A84 PolarHBondContact O-N 3.33Å
83	S	41.9	Very low	48.7	Very low	109 Å²	109	103.5 Å²	103.5	76%	0.762	52%	0.524	S	S	*	.	G	3₁₀ helix	trans	-73.9	-11.9	175.5	56.5	0	0	0	0	114.9	T81	T81-S83 PolarHBondContact O-N 3.46Å
84	A	42.3	Very low	49.7	Very low	61 Å²	61	100.7 Å²	100.7	50%	0.504	52%	0.518	S	S	.	.	G	3₁₀ helix	trans	-87.9	-8.3	-179.8	0	0	0	0	0	113	T81 P82	T81-A84 WeakPolarHBondContact O-CB 3.27Å; T81-A84 PolarHBondContact O-N 2.94Å; P82-A84 VanDerWaalsContact C-N 3.28Å; P82-A84 PolarHBondContact O-N 3.33Å
85	Y	45.5	Very low	50.5	Low	88 Å²	88	102.5 Å²	102.5	35%	0.345	52%	0.524	S	S	.	.	S	Bend	trans	-88.5	128.8	175.6	-74.8	-82.2	0	0	0	110.1	L80 S87	L80-Y85 HydrophobicContact CB-CE2 3.84Å; L80-Y85 HydrophobicContact CD1-CE1 4.5Å; L80-Y85 HydrophobicContact CD1-CE2 4.25Å; L80-Y85 WeakPolarHBondContact CD1-OH 3.44Å; Y85-S87 PolarHBondContact O-N 3.5Å
86	P	55.2	Low	51.4	Low	66 Å²	66	97.5 Å²	97.5	43%	0.429	50%	0.499	S	S	.	.	P	Polyproline II helix	trans	-57.7	132.6	170.5	-11.6	22.4	0	0	0	108.7	D90 F91	P86-D90 HydrophobicContact CB-CB 3.88Å; P86-F91 HydrophobicContact CB-CD2 3.91Å; P86-F91 HydrophobicContact CB-CE2 3.58Å; P86-F91 HydrophobicContact CB-CZ 4.07Å; P86-F91 HydrophobicContact CG-CE2 3.76Å; P86-F91 HydrophobicContact CG-CZ 3.8Å; P86-F91 WeakPolarHBondContact O-CE2 3.29Å
87	S	56.4	Low	52.6	Low	45 Å²	45	87.5 Å²	87.5	32%	0.315	46%	0.461	S	S	.	.	P	Polyproline II helix	trans	-63.5	160.1	175.1	67.5	0	0	0	0	110.1	Y85 S89 D90 F91	Y85-S87 PolarHBondContact O-N 3.5Å; S87-S89 PolarHBondContact O-N 2.95Å; S87-S89 VanDerWaalsContact O-N 3.15Å; S87-S89 PolarHBondContact OG-OG 3.18Å; S87-D90 WeakPolarHBondContact CB-OD2 3.33Å; S87-D90 PolarHBondContact N-OD2 3.46Å; S87-D90 WeakPolarHBondContact O-CB 3.49Å; S87-D90 PolarHBondContact O-N 2.93Å; S87-D90 PolarHBondContact OG-N 3.44Å; S87-D90 VanDerWaalsContact OG-N 3.15Å; S87-D90 PolarHBondContact OG-OD1 3.39Å; S87-D90 PolarHBondContact OG-OD2 2.88Å; S87-F91 WeakPolarHBondContact O-CD2 3.16Å; S87-F91 PolarHBondContact O-N 3.38Å; S87-F91 VanDerWaalsContact O-N 3.12Å
88	K	59.7	Low	54	Low	175 Å²	175	83 Å²	83	76%	0.761	45%	0.446	S	S	*	.	H	α-helix	trans	-53.2	-35.6	171.7	-175	177.7	178.5	180	0	111.7	I92	K88-I92 HydrophobicContact CG-CD1 4.08Å; K88-I92 WeakPolarHBondContact O-CB 3.19Å; K88-I92 WeakPolarHBondContact O-CD1 3.27Å; K88-I92 WeakPolarHBondContact O-CG1 3.1Å; K88-I92 PolarHBondContact O-N 3.26Å
89	S	61.8	Low	55.4	Low	70 Å²	70	79.1 Å²	79.1	49%	0.49	44%	0.435	S	S	.	.	H	α-helix	trans	-64.3	-38.8	173.6	28.9	0	0	0	0	113.2	S87 I92 T93	S87-S89 PolarHBondContact O-N 2.95Å; S87-S89 VanDerWaalsContact O-N 3.15Å; S87-S89 PolarHBondContact OG-OG 3.18Å; S89-I92 PolarHBondContact O-N 3.02Å; S89-T93 WeakPolarHBondContact O-CB 3.49Å; S89-T93 PolarHBondContact O-N 2.93Å; S89-T93 PolarHBondContact O-OG1 3.33Å
90	D	56.8	Low	56.8	Low	88 Å²	88	69.9 Å²	69.9	47%	0.471	40%	0.396	S	S	.	.	H	α-helix	trans	-66	-43.4	178.2	-58.9	-37	0	0	0	110.6	P86 S87 T93 M94	P86-D90 HydrophobicContact CB-CB 3.88Å; S87-D90 WeakPolarHBondContact CB-OD2 3.33Å; S87-D90 PolarHBondContact N-OD2 3.46Å; S87-D90 WeakPolarHBondContact O-CB 3.49Å; S87-D90 PolarHBondContact O-N 2.93Å; S87-D90 PolarHBondContact OG-N 3.44Å; S87-D90 VanDerWaalsContact OG-N 3.15Å; S87-D90 PolarHBondContact OG-OD1 3.39Å; S87-D90 PolarHBondContact OG-OD2 2.88Å; D90-T93 PolarHBondContact O-N 3.28Å; D90-M94 WeakPolarHBondContact O-CB 3.17Å; D90-M94 PolarHBondContact O-N 3.48Å
91	F	59.5	Low	58.5	Low	87 Å²	87	67.3 Å²	67.3	38%	0.382	38%	0.383	S	S	.	.	H	α-helix	trans	-62.2	-45.2	175.4	-82.6	-71.9	0	0	0	112.8	P86 S87 M94 E95	P86-F91 HydrophobicContact CB-CD2 3.91Å; P86-F91 HydrophobicContact CB-CE2 3.58Å; P86-F91 HydrophobicContact CB-CZ 4.07Å; P86-F91 HydrophobicContact CG-CE2 3.76Å; P86-F91 HydrophobicContact CG-CZ 3.8Å; P86-F91 WeakPolarHBondContact O-CE2 3.29Å; S87-F91 WeakPolarHBondContact O-CD2 3.16Å; S87-F91 PolarHBondContact O-N 3.38Å; S87-F91 VanDerWaalsContact O-N 3.12Å; F91-M94 HydrophobicContact CD1-CE 4.08Å; F91-M94 HydrophobicContact CE1-CE 4.46Å; F91-M94 PolarHBondContact O-N 3.05Å; F91-E95 WeakPolarHBondContact O-CB 3.35Å; F91-E95 WeakPolarHBondContact O-CG 3.15Å; F91-E95 PolarHBondContact O-N 3.47Å
92	I	63.1	Low	60	Low	79 Å²	79	64.5 Å²	64.5	41%	0.405	37%	0.369	S	S	.	.	H	α-helix	trans	-56.2	-56.2	174.7	-72.9	168	0	0	0	108.3	K88 S89 M94 E95 A96 Y495	K88-I92 HydrophobicContact CG-CD1 4.08Å; K88-I92 WeakPolarHBondContact O-CB 3.19Å; K88-I92 WeakPolarHBondContact O-CD1 3.27Å; K88-I92 WeakPolarHBondContact O-CG1 3.1Å; K88-I92 PolarHBondContact O-N 3.26Å; S89-I92 PolarHBondContact O-N 3.02Å; I92-M94 VanDerWaalsContact C-N 3.34Å; I92-M94 PolarHBondContact O-N 2.95Å; I92-E95 PolarHBondContact O-N 2.65Å; I92-E95 VanDerWaalsContact O-N 3.1Å; I92-A96 PolarHBondContact O-N 3.44Å; I92-Y495 HydrophobicContact CG2-CE2 3.99Å; I92-Y495 WeakPolarHBondContact CG2-OH 3.4Å; I92-Y495 WeakPolarHBondContact O-CE1 3.36Å; I92-Y495 PolarHBondContact O-OH 3.5Å
93	T	62.6	Low	61.6	Low	51 Å²	51	61.8 Å²	61.8	31%	0.313	35%	0.348	S	S	.	.	H	α-helix	trans	-55.9	-45.4	-177.7	-56.4	0	0	0	0	112.8	S89 D90 A96 N97	S89-T93 WeakPolarHBondContact O-CB 3.49Å; S89-T93 PolarHBondContact O-N 2.93Å; S89-T93 PolarHBondContact O-OG1 3.33Å; D90-T93 PolarHBondContact O-N 3.28Å; T93-A96 WeakPolarHBondContact O-CB 2.86Å; T93-A96 PolarHBondContact O-N 3.2Å; T93-N97 VanDerWaalsContact O-CG 3.31Å; T93-N97 PolarHBondContact O-N 2.86Å; T93-N97 VanDerWaalsContact O-N 3.1Å; T93-N97 PolarHBondContact O-ND2 3.24Å
94	M	61.8	Low	63.3	Low	92 Å²	92	57 Å²	57	45%	0.453	31%	0.313	S	S	.	.	H	α-helix	trans	-59.5	-47.7	176.5	-175.5	-176.2	73.8	0	0	111.9	D90 F91 I92 A96 N97 E98	D90-M94 WeakPolarHBondContact O-CB 3.17Å; D90-M94 PolarHBondContact O-N 3.48Å; F91-M94 HydrophobicContact CD1-CE 4.08Å; F91-M94 HydrophobicContact CE1-CE 4.46Å; F91-M94 PolarHBondContact O-N 3.05Å; I92-M94 VanDerWaalsContact C-N 3.34Å; I92-M94 PolarHBondContact O-N 2.95Å; M94-A96 PolarHBondContact O-N 3.32Å; M94-N97 PolarHBondContact O-N 3.13Å; M94-E98 PolarHBondContact O-N 3.14Å; M94-E98 VanDerWaalsContact O-N 3.07Å
95	E	60.1	Low	64.9	Low	56 Å²	56	59.7 Å²	59.7	26%	0.262	32%	0.315	S	S	.	.	H	α-helix	trans	-63.2	-31.4	177.5	-72.1	-83.2	154.1	0	0	111.9	F91 I92 A99 Y495 R502 R506	F91-E95 WeakPolarHBondContact O-CB 3.35Å; F91-E95 WeakPolarHBondContact O-CG 3.15Å; F91-E95 PolarHBondContact O-N 3.47Å; I92-E95 PolarHBondContact O-N 2.65Å; I92-E95 VanDerWaalsContact O-N 3.1Å; E95-A99 WeakPolarHBondContact O-CB 3.37Å; E95-A99 PolarHBondContact O-N 3.48Å; E95-Y495 HydrophobicContact CB-CD1 4.35Å; E95-Y495 HydrophobicContact CB-CE1 3.82Å; E95-R502 IonicContact OE2-NH1 2.78Å; E95-R506 IonicContact OE1-CZ 3.31Å; E95-R506 IonicContact OE1-NE 2.75Å; E95-R506 IonicContact OE1-NH2 3.71Å; E95-R506 PolarHBondContact OE1-NH2 3.5Å; E95-R506 IonicContact OE2-NH2 3.95Å; E95-R506 PolarHBondContact OE2-NH2 2.95Å
96	A	66.3	Low	66.1	Low	8 Å²	8	62.3 Å²	62.3	7%	0.066	33%	0.329	C	S	.	.	H	α-helix	trans	-69	-43.8	178.6	0	0	0	0	0	109.9	I92 T93 M94 A99 L100 Y495	I92-A96 PolarHBondContact O-N 3.44Å; T93-A96 WeakPolarHBondContact O-CB 2.86Å; T93-A96 PolarHBondContact O-N 3.2Å; M94-A96 PolarHBondContact O-N 3.32Å; A96-A99 PolarHBondContact O-N 3.12Å; A96-L100 WeakPolarHBondContact O-CD1 3.08Å; A96-L100 VanDerWaalsContact O-CG 3.24Å; A96-L100 WeakPolarHBondContact O-CG 3.4Å; A96-L100 PolarHBondContact O-N 2.7Å; A96-Y495 HydrophobicContact CB-CE1 3.63Å; A96-Y495 HydrophobicContact CB-CE2 4.5Å; A96-Y495 VanDerWaalsContact CB-CZ 3.46Å; A96-Y495 WeakPolarHBondContact CB-OH 3.41Å
97	N	67.3	Low	67.1	Low	5 Å²	5	62.9 Å²	62.9	3%	0.027	33%	0.325	C	S	.	.	H	α-helix	trans	-64.5	-42.8	-179.5	-66.4	-24.5	0	0	0	111	T93 M94 L100 I101 Y118 Q124 I128	T93-N97 VanDerWaalsContact O-CG 3.31Å; T93-N97 PolarHBondContact O-N 2.86Å; T93-N97 VanDerWaalsContact O-N 3.1Å; T93-N97 PolarHBondContact O-ND2 3.24Å; M94-N97 PolarHBondContact O-N 3.13Å; N97-L100 WeakPolarHBondContact O-CB 3.5Å; N97-L100 PolarHBondContact O-N 2.83Å; N97-I101 WeakPolarHBondContact O-CD1 3.4Å; N97-I101 WeakPolarHBondContact O-CG1 3.49Å; N97-I101 PolarHBondContact O-N 2.81Å; N97-Y118 PolarHBondContact OD1-OH 3.34Å; N97-Q124 PolarHBondContact ND2-OE1 2.9Å; N97-I128 HydrophobicContact CB-CD1 3.34Å; N97-I128 HydrophobicContact CB-CG1 3.94Å; N97-I128 VanDerWaalsContact ND2-CD1 3.29Å; N97-I128 WeakPolarHBondContact ND2-CD1 3.47Å
98	E	69.5	Low	68	Low	60 Å²	60	63.7 Å²	63.7	28%	0.28	33%	0.33	S	S	.	.	H	α-helix	trans	-64.5	-39.5	173.6	-72.8	-56.6	129.5	0	0	112.6	M94 L100 I101 A102 H127 K131	M94-E98 PolarHBondContact O-N 3.14Å; M94-E98 VanDerWaalsContact O-N 3.07Å; E98-L100 VanDerWaalsContact C-N 3.29Å; E98-L100 PolarHBondContact O-N 3.1Å; E98-I101 PolarHBondContact O-N 3.32Å; E98-A102 WeakPolarHBondContact O-CB 3.41Å; E98-A102 PolarHBondContact O-N 3.2Å; E98-H127 IonicContact OE1-CD2 3.41Å; E98-H127 PolarHBondContact OE1-CD2 3.25Å; E98-H127 IonicContact OE1-NE2 3.69Å; E98-H127 PolarHBondContact OE1-NE2 3.33Å; E98-K131 IonicContact OE1-NZ 3.27Å; E98-K131 IonicContact OE2-NZ 2.72Å; E98-K131 PolarHBondContact OE2-NZ 3.43Å
99	A	70	Confident	68.6	Low	36 Å²	36	60.7 Å²	60.7	30%	0.298	32%	0.318	S	S	.	.	H	α-helix	trans	-62.9	-37	175	0	0	0	0	0	112.2	E95 A96 L103	E95-A99 WeakPolarHBondContact O-CB 3.37Å; E95-A99 PolarHBondContact O-N 3.48Å; A96-A99 PolarHBondContact O-N 3.12Å; A99-L103 WeakPolarHBondContact O-CB 3.34Å; A99-L103 PolarHBondContact O-N 3Å
100	L	70.8	Confident	69.3	Low	23 Å²	23	61.6 Å²	61.6	12%	0.12	31%	0.313	C	S	.	.	H	α-helix	trans	-68	-45	175	-72.1	161.5	0	0	0	112.1	A96 N97 E98 A102 L103 F104 R117 Y118	A96-L100 WeakPolarHBondContact O-CD1 3.08Å; A96-L100 VanDerWaalsContact O-CG 3.24Å; A96-L100 WeakPolarHBondContact O-CG 3.4Å; A96-L100 PolarHBondContact O-N 2.7Å; N97-L100 WeakPolarHBondContact O-CB 3.5Å; N97-L100 PolarHBondContact O-N 2.83Å; E98-L100 VanDerWaalsContact C-N 3.29Å; E98-L100 PolarHBondContact O-N 3.1Å; L100-A102 VanDerWaalsContact C-N 3.32Å; L100-A102 PolarHBondContact O-N 3.41Å; L100-L103 WeakPolarHBondContact O-CB 3.46Å; L100-L103 PolarHBondContact O-N 3.43Å; L100-L103 VanDerWaalsContact O-N 3.14Å; L100-F104 HydrophobicContact CB-CD2 4.29Å; L100-F104 HydrophobicContact CB-CE2 3.9Å; L100-F104 HydrophobicContact CD2-CE2 4.11Å; L100-F104 HydrophobicContact CD2-CZ 4.28Å; L100-F104 WeakPolarHBondContact O-CD2 3.44Å; L100-F104 WeakPolarHBondContact O-CG 3.42Å; L100-F104 PolarHBondContact O-N 3.22Å; L100-R117 VanDerWaalsContact CD1-NE 3.27Å; L100-Y118 VanDerWaalsContact CD1-OH 3.29Å; L100-Y118 WeakPolarHBondContact CD1-OH 3.44Å
101	I	74.5	Confident	70.2	Confident	2 Å²	2	57.7 Å²	57.7	1%	0.01	29%	0.292	C	S	.	.	H	α-helix	trans	-54.2	-52.7	174.2	-76	157.3	0	0	0	109.6	N97 E98 L103 F104 E105 I128 K131 L132 I135	N97-I101 WeakPolarHBondContact O-CD1 3.4Å; N97-I101 WeakPolarHBondContact O-CG1 3.49Å; N97-I101 PolarHBondContact O-N 2.81Å; E98-I101 PolarHBondContact O-N 3.32Å; I101-L103 VanDerWaalsContact C-N 3.25Å; I101-L103 PolarHBondContact O-N 3.18Å; I101-F104 PolarHBondContact O-N 3.09Å; I101-F104 VanDerWaalsContact O-N 3.13Å; I101-E105 HydrophobicContact CG2-CG 4.47Å; I101-E105 WeakPolarHBondContact O-CG 3.31Å; I101-E105 PolarHBondContact O-N 3.19Å; I101-I128 HydrophobicContact CD1-CB 4.3Å; I101-I128 HydrophobicContact CD1-CG1 3.96Å; I101-I128 HydrophobicContact CD1-CG2 4.2Å; I101-K131 HydrophobicContact CD1-CB 4.12Å; I101-K131 HydrophobicContact CD1-CD 3.95Å; I101-K131 HydrophobicContact CG1-CB 4.2Å; I101-K131 HydrophobicContact CG1-CD 4.42Å; I101-K131 HydrophobicContact CG2-CB 4.16Å; I101-K131 HydrophobicContact CG2-CD 3.5Å; I101-K131 VanDerWaalsContact CG2-CD 3.5Å; I101-K131 HydrophobicContact CG2-CG 4.48Å; I101-L132 HydrophobicContact CG1-CD2 4.3Å; I101-I135 HydrophobicContact CG2-CD1 4.23Å
102	A	73.8	Confident	70.9	Confident	35 Å²	35	56.9 Å²	56.9	29%	0.289	29%	0.292	S	S	.	.	H	α-helix	trans	-62.9	-31.6	179.3	0	0	0	0	0	112.9	E98 L100 K106	E98-A102 WeakPolarHBondContact O-CB 3.41Å; E98-A102 PolarHBondContact O-N 3.2Å; L100-A102 VanDerWaalsContact C-N 3.32Å; L100-A102 PolarHBondContact O-N 3.41Å; A102-K106 WeakPolarHBondContact O-CG 3.39Å; A102-K106 PolarHBondContact O-N 2.98Å
103	L	74.9	Confident	71.6	Confident	62 Å²	62	58.8 Å²	58.8	33%	0.325	30%	0.298	S	S	.	.	H	α-helix	trans	-65.8	-49.9	172.8	179.4	70.4	0	0	0	110.5	A99 L100 I101 K106 H107 F110	A99-L103 WeakPolarHBondContact O-CB 3.34Å; A99-L103 PolarHBondContact O-N 3Å; L100-L103 WeakPolarHBondContact O-CB 3.46Å; L100-L103 PolarHBondContact O-N 3.43Å; L100-L103 VanDerWaalsContact O-N 3.14Å; I101-L103 VanDerWaalsContact C-N 3.25Å; I101-L103 PolarHBondContact O-N 3.18Å; L103-K106 PolarHBondContact O-N 2.66Å; L103-H107 WeakPolarHBondContact O-CA 3.35Å; L103-H107 WeakPolarHBondContact O-CB 3.24Å; L103-H107 PolarHBondContact O-N 2.98Å; L103-F110 HydrophobicContact CD1-CD2 4.26Å; L103-F110 HydrophobicContact CD1-CE2 4.45Å; L103-F110 HydrophobicContact CG-CD2 4.33Å
104	F	77.1	Confident	72.4	Confident	9 Å²	9	56.4 Å²	56.4	4%	0.039	28%	0.283	C	S	.	.	H	α-helix	trans	-71.4	-31.5	-176.8	-64.4	-51.7	0	0	0	113.6	L100 I101 K106 H107 P108 F110 L111 L114 L132 I135	L100-F104 HydrophobicContact CB-CD2 4.29Å; L100-F104 HydrophobicContact CB-CE2 3.9Å; L100-F104 HydrophobicContact CD2-CE2 4.11Å; L100-F104 HydrophobicContact CD2-CZ 4.28Å; L100-F104 WeakPolarHBondContact O-CD2 3.44Å; L100-F104 WeakPolarHBondContact O-CG 3.42Å; L100-F104 PolarHBondContact O-N 3.22Å; I101-F104 PolarHBondContact O-N 3.09Å; I101-F104 VanDerWaalsContact O-N 3.13Å; F104-K106 VanDerWaalsContact C-N 3.29Å; F104-K106 PolarHBondContact O-N 2.83Å; F104-H107 CarbonylContact O-C 3.6Å; F104-P108 WeakPolarHBondContact O-CA 3.43Å; F104-F110 HydrophobicContact CD1-CB 4.03Å; F104-F110 HydrophobicContact CE1-CB 3.82Å; F104-F110 VanDerWaalsContact CE1-O 3.31Å; F104-F110 WeakPolarHBondContact CE1-O 3.35Å; F104-L111 HydrophobicContact CB-CD2 3.84Å; F104-L111 HydrophobicContact CD1-CD2 3.99Å; F104-L111 HydrophobicContact CD1-CG 4.45Å; F104-L111 HydrophobicContact CG-CD2 3.94Å; F104-L114 HydrophobicContact CD2-CD2 3.74Å; F104-L114 HydrophobicContact CD2-CG 4.23Å; F104-L114 HydrophobicContact CE1-CD2 4.36Å; F104-L114 HydrophobicContact CE1-CG 4.15Å; F104-L114 HydrophobicContact CE2-CD2 3.11Å; F104-L114 HydrophobicContact CE2-CG 3.77Å; F104-L114 HydrophobicContact CZ-CD2 3.49Å; F104-L114 VanDerWaalsContact CZ-CD2 3.49Å; F104-L114 HydrophobicContact CZ-CG 3.71Å; F104-L132 HydrophobicContact CD2-CD2 4.11Å; F104-I135 HydrophobicContact CB-CD1 4.32Å; F104-I135 HydrophobicContact CB-CG2 4.09Å
105	E	75.7	Confident	73.2	Confident	116 Å²	116	52 Å²	52	54%	0.542	26%	0.261	S	S	.	.	H	α-helix	trans	-61.3	-39.1	170.9	-74.8	175.2	169.2	0	0	111.8	I101 I135	I101-E105 HydrophobicContact CG2-CG 4.47Å; I101-E105 WeakPolarHBondContact O-CG 3.31Å; I101-E105 PolarHBondContact O-N 3.19Å; E105-I135 HydrophobicContact CG-CD1 3.62Å; E105-I135 HydrophobicContact CG-CG1 3.88Å
106	K	71.5	Confident	73.8	Confident	144 Å²	144	51.7 Å²	51.7	63%	0.626	27%	0.265	S	S	*	.	H	α-helix	trans	-85.6	-31.7	-179.2	-71	-178.3	179.9	-178.1	0	113.6	A102 L103 F104	A102-K106 WeakPolarHBondContact O-CG 3.39Å; A102-K106 PolarHBondContact O-N 2.98Å; L103-K106 PolarHBondContact O-N 2.66Å; F104-K106 VanDerWaalsContact C-N 3.29Å; F104-K106 PolarHBondContact O-N 2.83Å
107	H	75.6	Confident	74.2	Confident	78 Å²	78	54.9 Å²	54.9	36%	0.361	28%	0.275	S	S	.	.			trans	-132.5	69.6	-171.7	-65.1	-74.5	0	0	0	110.4	L103 F104 E109 F110	L103-H107 WeakPolarHBondContact O-CA 3.35Å; L103-H107 WeakPolarHBondContact O-CB 3.24Å; L103-H107 PolarHBondContact O-N 2.98Å; F104-H107 CarbonylContact O-C 3.6Å; H107-E109 VanDerWaalsContact CA-OE2 3.22Å; H107-E109 WeakPolarHBondContact CA-OE2 3.45Å; H107-E109 WeakPolarHBondContact CB-OE1 3.3Å; H107-E109 IonicContact CG-OE1 3.67Å; H107-E109 IonicContact ND1-OE1 3.75Å; H107-E109 PolarHBondContact ND1-OE1 2.85Å; H107-E109 PolarHBondContact O-N 2.72Å; H107-E109 VanDerWaalsContact O-N 3.1Å; H107-F110 HydrophobicContact CB-CD2 3.33Å; H107-F110 HydrophobicContact CB-CE2 3.56Å; H107-F110 HydrophobicContact CB-CG 4.44Å; H107-F110 AromaticContact CG-CE2 3.87Å; H107-F110 PolarHBondContact O-N 3.1Å
108	P	75.4	Confident	74.9	Confident	62 Å²	62	54.9 Å²	54.9	40%	0.403	28%	0.275	S	S	.	.	G	3₁₀ helix	trans	-60.9	-18.8	-179.8	26	-35	0	0	0	112.8	F104 F110 L111	F104-P108 WeakPolarHBondContact O-CA 3.43Å; P108-F110 PolarHBondContact O-N 3.4Å; P108-F110 VanDerWaalsContact O-N 3.14Å; P108-L111 HydrophobicContact CB-CD1 3.91Å; P108-L111 HydrophobicContact CB-CG 4.47Å; P108-L111 VanDerWaalsContact O-CB 3.24Å; P108-L111 WeakPolarHBondContact O-CB 3.44Å; P108-L111 WeakPolarHBondContact O-CD1 3.41Å; P108-L111 WeakPolarHBondContact O-CG 3.17Å; P108-L111 PolarHBondContact O-N 3.21Å
109	E	71.9	Confident	75.7	Confident	111 Å²	111	53 Å²	53	52%	0.519	27%	0.266	S	S	.	.	G	3₁₀ helix	trans	-57.9	-22.7	171.8	64.3	-87.3	-161.2	0	0	113.7	H107	H107-E109 VanDerWaalsContact CA-OE2 3.22Å; H107-E109 WeakPolarHBondContact CA-OE2 3.45Å; H107-E109 WeakPolarHBondContact CB-OE1 3.3Å; H107-E109 IonicContact CG-OE1 3.67Å; H107-E109 IonicContact ND1-OE1 3.75Å; H107-E109 PolarHBondContact ND1-OE1 2.85Å; H107-E109 PolarHBondContact O-N 2.72Å; H107-E109 VanDerWaalsContact O-N 3.1Å
110	F	76.6	Confident	76.5	Confident	89 Å²	89	52.3 Å²	52.3	39%	0.39	26%	0.257	S	S	.	.	G	3₁₀ helix	trans	-86.5	-2.7	176.4	-62.5	-52.7	0	0	0	113.8	L103 F104 H107 P108 N112 K113	L103-F110 HydrophobicContact CD1-CD2 4.26Å; L103-F110 HydrophobicContact CD1-CE2 4.45Å; L103-F110 HydrophobicContact CG-CD2 4.33Å; F104-F110 HydrophobicContact CD1-CB 4.03Å; F104-F110 HydrophobicContact CE1-CB 3.82Å; F104-F110 VanDerWaalsContact CE1-O 3.31Å; F104-F110 WeakPolarHBondContact CE1-O 3.35Å; H107-F110 HydrophobicContact CB-CD2 3.33Å; H107-F110 HydrophobicContact CB-CE2 3.56Å; H107-F110 HydrophobicContact CB-CG 4.44Å; H107-F110 AromaticContact CG-CE2 3.87Å; H107-F110 PolarHBondContact O-N 3.1Å; P108-F110 PolarHBondContact O-N 3.4Å; P108-F110 VanDerWaalsContact O-N 3.14Å; F110-N112 PolarHBondContact O-N 2.71Å; F110-N112 VanDerWaalsContact O-N 3.13Å; F110-K113 VanDerWaalsContact O-CB 3.31Å; F110-K113 WeakPolarHBondContact O-CB 3.2Å; F110-K113 PolarHBondContact O-N 2.94Å
111	L	76.8	Confident	77.2	Confident	6 Å²	6	55.5 Å²	55.5	3%	0.031	27%	0.271	C	S	.	.	G	3₁₀ helix	trans	-57.6	-30.1	-178.9	-73.3	170.4	0	0	0	112.9	F104 P108 K113 L114 I135 S139 V372	F104-L111 HydrophobicContact CB-CD2 3.84Å; F104-L111 HydrophobicContact CD1-CD2 3.99Å; F104-L111 HydrophobicContact CD1-CG 4.45Å; F104-L111 HydrophobicContact CG-CD2 3.94Å; P108-L111 HydrophobicContact CB-CD1 3.91Å; P108-L111 HydrophobicContact CB-CG 4.47Å; P108-L111 VanDerWaalsContact O-CB 3.24Å; P108-L111 WeakPolarHBondContact O-CB 3.44Å; P108-L111 WeakPolarHBondContact O-CD1 3.41Å; P108-L111 WeakPolarHBondContact O-CG 3.17Å; P108-L111 PolarHBondContact O-N 3.21Å; L111-K113 PolarHBondContact O-N 3.34Å; L111-K113 VanDerWaalsContact O-N 3.08Å; L111-L114 HydrophobicContact CB-CD1 4.49Å; L111-L114 HydrophobicContact CD2-CD1 3.41Å; L111-L114 VanDerWaalsContact CD2-CD1 3.41Å; L111-L114 HydrophobicContact CD2-CG 4.3Å; L111-L114 VanDerWaalsContact O-CB 3.24Å; L111-L114 WeakPolarHBondContact O-CB 3.46Å; L111-L114 PolarHBondContact O-N 2.97Å; L111-I135 HydrophobicContact CD1-CG2 4.11Å; L111-I135 HydrophobicContact CD2-CG2 3.74Å; L111-I135 HydrophobicContact CG-CG2 4.43Å; L111-S139 WeakPolarHBondContact CD1-OG 3.18Å; L111-V372 HydrophobicContact CB-CB 4.08Å; L111-V372 HydrophobicContact CB-CG1 4Å; L111-V372 HydrophobicContact CD1-CG1 4.37Å
112	N	73.7	Confident	77.7	Confident	71 Å²	71	56.9 Å²	56.9	38%	0.38	28%	0.28	S	S	.	.	G	3₁₀ helix	trans	-62.3	-14.6	173.7	67.3	8.9	0	0	0	114.2	F110 V372	F110-N112 PolarHBondContact O-N 2.71Å; F110-N112 VanDerWaalsContact O-N 3.13Å; N112-V372 VanDerWaalsContact CA-O 3.27Å; N112-V372 WeakPolarHBondContact CA-O 3.34Å
113	K	77.6	Confident	78.2	Confident	119 Å²	119	55.3 Å²	55.3	52%	0.517	27%	0.267	S	S	.	.	G	3₁₀ helix	trans	-88.3	-11.1	173.9	-56.7	-52.4	-179.1	-174.1	0	113	F110 L111 S115 S116	F110-K113 VanDerWaalsContact O-CB 3.31Å; F110-K113 WeakPolarHBondContact O-CB 3.2Å; F110-K113 PolarHBondContact O-N 2.94Å; L111-K113 PolarHBondContact O-N 3.34Å; L111-K113 VanDerWaalsContact O-N 3.08Å; K113-S115 VanDerWaalsContact C-N 3.28Å; K113-S115 PolarHBondContact O-N 3.34Å; K113-S116 PolarHBondContact O-N 2.91Å; K113-S116 VanDerWaalsContact O-N 3.16Å; K113-S116 PolarHBondContact O-OG 3.37Å
114	L	80.1	Confident	78	Confident	1 Å²	1	56.8 Å²	56.8	1%	0.005	27%	0.272	C	S	.	.	H	α-helix	trans	-56.4	-45	177.3	-82.3	172.5	0	0	0	111.6	F104 L111 S116 R117 Y118 L132 I136 L369 V372	F104-L114 HydrophobicContact CD2-CD2 3.74Å; F104-L114 HydrophobicContact CD2-CG 4.23Å; F104-L114 HydrophobicContact CE1-CD2 4.36Å; F104-L114 HydrophobicContact CE1-CG 4.15Å; F104-L114 HydrophobicContact CE2-CD2 3.11Å; F104-L114 HydrophobicContact CE2-CG 3.77Å; F104-L114 HydrophobicContact CZ-CD2 3.49Å; F104-L114 VanDerWaalsContact CZ-CD2 3.49Å; F104-L114 HydrophobicContact CZ-CG 3.71Å; L111-L114 HydrophobicContact CB-CD1 4.49Å; L111-L114 HydrophobicContact CD2-CD1 3.41Å; L111-L114 VanDerWaalsContact CD2-CD1 3.41Å; L111-L114 HydrophobicContact CD2-CG 4.3Å; L111-L114 VanDerWaalsContact O-CB 3.24Å; L111-L114 WeakPolarHBondContact O-CB 3.46Å; L111-L114 PolarHBondContact O-N 2.97Å; L114-S116 VanDerWaalsContact C-N 3.26Å; L114-S116 PolarHBondContact O-N 3.47Å; L114-R117 PolarHBondContact O-N 2.87Å; L114-Y118 HydrophobicContact CD2-CD2 3.73Å; L114-Y118 HydrophobicContact CD2-CE2 3.68Å; L114-Y118 PolarHBondContact O-N 3.39Å; L114-L132 HydrophobicContact CD1-CD2 4.45Å; L114-L132 HydrophobicContact CD2-CD2 3.91Å; L114-I136 HydrophobicContact CD1-CD1 4.08Å; L114-I136 HydrophobicContact CD1-CG1 4Å; L114-L369 HydrophobicContact CB-CD2 3.8Å; L114-V372 HydrophobicContact CB-CG2 4.36Å; L114-V372 HydrophobicContact CD1-CG2 4.2Å
115	S	78.2	Confident	77.9	Confident	0 Å²	0	59.5 Å²	59.5	0%	0	29%	0.292	C	S	.	.	H	α-helix	trans	-61.7	-35.6	-179.2	-50.3	0	0	0	0	112.4	K113 R117 F119 L369	K113-S115 VanDerWaalsContact C-N 3.28Å; K113-S115 PolarHBondContact O-N 3.34Å; S115-R117 PolarHBondContact O-N 2.93Å; S115-R117 VanDerWaalsContact O-N 3.17Å; S115-F119 WeakPolarHBondContact O-CB 3.22Å; S115-F119 PolarHBondContact O-N 2.91Å; S115-L369 PolarHBondContact OG-O 3.36Å
116	S	72.4	Confident	78.1	Confident	48 Å²	48	55.6 Å²	55.6	34%	0.336	28%	0.278	S	S	.	.	H	α-helix	trans	-63.4	-22.3	176.2	73.7	0	0	0	0	113.7	K113 L114	K113-S116 PolarHBondContact O-N 2.91Å; K113-S116 VanDerWaalsContact O-N 3.16Å; K113-S116 PolarHBondContact O-OG 3.37Å; L114-S116 VanDerWaalsContact C-N 3.26Å; L114-S116 PolarHBondContact O-N 3.47Å
117	R	74.2	Confident	78.5	Confident	75 Å²	75	51.8 Å²	51.8	28%	0.283	26%	0.262	S	S	.	.	H	α-helix	trans	-100.8	-42.2	-178.1	-175.2	173.2	-177.4	128.2	0.1	113.1	L100 L114 S115 Q121	L100-R117 VanDerWaalsContact CD1-NE 3.27Å; L114-R117 PolarHBondContact O-N 2.87Å; S115-R117 PolarHBondContact O-N 2.93Å; S115-R117 VanDerWaalsContact O-N 3.17Å; R117-Q121 PolarHBondContact O-NE2 3.44Å
118	Y	83.7	Confident	78.8	Confident	6 Å²	6	48.5 Å²	48.5	2%	0.024	25%	0.247	C	C	.	.	H	α-helix	trans	-109.5	-1.8	-168.6	-66.5	-72.2	0	0	0	114.5	N97 L100 L114 N120 Q121 F123 L132	N97-Y118 PolarHBondContact OD1-OH 3.34Å; L100-Y118 VanDerWaalsContact CD1-OH 3.29Å; L100-Y118 WeakPolarHBondContact CD1-OH 3.44Å; L114-Y118 HydrophobicContact CD2-CD2 3.73Å; L114-Y118 HydrophobicContact CD2-CE2 3.68Å; L114-Y118 PolarHBondContact O-N 3.39Å; Y118-N120 PolarHBondContact O-N 3.42Å; Y118-Q121 WeakPolarHBondContact O-CB 3.41Å; Y118-Q121 PolarHBondContact O-N 3.49Å; Y118-F123 AromaticContact CD1-CD1 3.92Å; Y118-F123 HydrophobicContact CD1-CD1 3.92Å; Y118-F123 HydrophobicContact CD1-CE1 4.11Å; Y118-F123 HydrophobicContact CD2-CE1 4.03Å; Y118-F123 HydrophobicContact CE1-CD1 4.41Å; Y118-F123 AromaticContact CG-CD1 3.99Å; Y118-F123 HydrophobicContact CG-CD1 3.99Å; Y118-F123 AromaticContact CG-CE1 3.68Å; Y118-F123 HydrophobicContact CG-CE1 3.68Å; Y118-L132 HydrophobicContact CE2-CD1 4.15Å
119	F	85.5	Confident	79.5	Confident	20 Å²	20	46.3 Å²	46.3	9%	0.088	23%	0.231	C	C	.	.	T	Hydrogen-bonded Turn	trans	-57	134.4	177	174.1	-122.8	0	0	0	111	S115 Q121 I451 I456 I459 F460 L463	S115-F119 WeakPolarHBondContact O-CB 3.22Å; S115-F119 PolarHBondContact O-N 2.91Å; F119-Q121 PolarHBondContact O-N 2.88Å; F119-I451 HydrophobicContact CE1-CG2 4.5Å; F119-I451 HydrophobicContact CE2-CG2 4.19Å; F119-I451 HydrophobicContact CZ-CG2 3.66Å; F119-I456 HydrophobicContact CD1-CD1 4.01Å; F119-I456 HydrophobicContact CE1-CD1 3.36Å; F119-I456 HydrophobicContact CE1-CG1 4.03Å; F119-I456 HydrophobicContact CZ-CD1 4.1Å; F119-I459 HydrophobicContact CD2-CG2 4.09Å; F119-I459 HydrophobicContact CE1-CB 4.43Å; F119-I459 HydrophobicContact CE1-CG2 4.45Å; F119-I459 HydrophobicContact CE2-CB 3.95Å; F119-I459 HydrophobicContact CE2-CG2 3.28Å; F119-I459 HydrophobicContact CZ-CB 3.6Å; F119-I459 HydrophobicContact CZ-CD1 4.42Å; F119-I459 HydrophobicContact CZ-CG2 3.5Å; F119-I459 VanDerWaalsContact CZ-CG2 3.5Å; F119-F460 HydrophobicContact CD1-CB 4.11Å; F119-F460 AromaticContact CD1-CD2 3.88Å; F119-F460 HydrophobicContact CD1-CD2 3.88Å; F119-F460 HydrophobicContact CE1-CB 4Å; F119-L463 HydrophobicContact CB-CD1 4.27Å; F119-L463 HydrophobicContact CD2-CD1 3.49Å; F119-L463 VanDerWaalsContact CD2-CD1 3.49Å; F119-L463 HydrophobicContact CE2-CD1 4.06Å; F119-L463 HydrophobicContact CG-CD1 3.97Å
120	N	86.5	Confident	80.4	Confident	21 Å²	21	42 Å²	42	11%	0.112	21%	0.21	C	C	.	.	T	Hydrogen-bonded Turn	trans	61.3	19.2	-175.2	-155.5	25.8	0	0	0	114.6	Y118 Y362 Q448 I451 I456	Y118-N120 PolarHBondContact O-N 3.42Å; N120-Y362 PolarHBondContact OD1-OH 3.19Å; N120-Q448 PolarHBondContact ND2-O 3.46Å; N120-Q448 VanDerWaalsContact OD1-CA 3.29Å; N120-Q448 WeakPolarHBondContact OD1-CA 3.29Å; N120-Q448 WeakPolarHBondContact OD1-CG 3.32Å; N120-I451 HydrophobicContact CB-CG2 4.36Å; N120-I456 HydrophobicContact CB-CD1 4.35Å
121	Q	84.8	Confident	80.9	Confident	90 Å²	90	40.2 Å²	40.2	42%	0.421	20%	0.202	S	C	.	.	S	Bend	trans	-119.9	145.4	173.7	-59.2	179.4	17.2	0	0	110.5	R117 Y118 F119 Q366	R117-Q121 PolarHBondContact O-NE2 3.44Å; Y118-Q121 WeakPolarHBondContact O-CB 3.41Å; Y118-Q121 PolarHBondContact O-N 3.49Å; F119-Q121 PolarHBondContact O-N 2.88Å; Q121-Q366 PolarHBondContact O-NE2 2.8Å
122	T	85	Confident	81.4	Confident	31 Å²	31	40 Å²	40	19%	0.19	20%	0.2	C	C	.	.	P	Polyproline II helix	trans	-74.5	138.4	168.4	-50.6	0	0	0	0	109.4	Q124 K444	T122-Q124 PolarHBondContact O-N 2.85Å; T122-K444 PolarHBondContact OG1-NZ 2.91Å
123	F	85.6	Confident	82.3	Confident	2 Å²	2	36.6 Å²	36.6	1%	0.009	18%	0.182	C	C	.	.	P	Polyproline II helix	trans	-62.3	122.7	169.2	-63.3	-35.5	0	0	0	109.8	Y118 S125 R129 L132 W133 D365 L369	Y118-F123 AromaticContact CD1-CD1 3.92Å; Y118-F123 HydrophobicContact CD1-CD1 3.92Å; Y118-F123 HydrophobicContact CD1-CE1 4.11Å; Y118-F123 HydrophobicContact CD2-CE1 4.03Å; Y118-F123 HydrophobicContact CE1-CD1 4.41Å; Y118-F123 AromaticContact CG-CD1 3.99Å; Y118-F123 HydrophobicContact CG-CD1 3.99Å; Y118-F123 AromaticContact CG-CE1 3.68Å; Y118-F123 HydrophobicContact CG-CE1 3.68Å; F123-S125 PolarHBondContact O-N 3.46Å; F123-R129 HydrophobicContact CB-CB 4.03Å; F123-R129 HydrophobicContact CD2-CB 4.3Å; F123-R129 HydrophobicContact CD2-CG 4.21Å; F123-R129 PolarHBondContact O-NH2 3.36Å; F123-L132 HydrophobicContact CD1-CD1 3.72Å; F123-L132 HydrophobicContact CD2-CD1 4.32Å; F123-L132 HydrophobicContact CE1-CD1 3.75Å; F123-L132 HydrophobicContact CE2-CB 4.32Å; F123-L132 HydrophobicContact CE2-CD1 4.36Å; F123-L132 HydrophobicContact CG-CD1 4.03Å; F123-L132 HydrophobicContact CZ-CD1 4.09Å; F123-W133 AromaticContact CD2-CD1 3.95Å; F123-W133 AromaticContact CD2-NE1 3.8Å; F123-W133 AromaticContact CE2-CD1 3.72Å; F123-W133 AromaticContact CE2-NE1 3.69Å; F123-D365 HydrophobicContact CD2-CB 3.87Å; F123-D365 WeakPolarHBondContact CD2-OD1 3.47Å; F123-D365 HydrophobicContact CE2-CB 3.89Å; F123-D365 HydrophobicContact CG-CB 4.36Å; F123-D365 HydrophobicContact CZ-CB 4.41Å; F123-D365 PolarHBondContact N-OD2 3Å; F123-L369 HydrophobicContact CE1-CD2 4.1Å; F123-L369 HydrophobicContact CE1-CG 4.43Å; F123-L369 HydrophobicContact CZ-CD2 3.8Å; F123-L369 HydrophobicContact CZ-CG 4Å
124	Q	70.8	Confident	82.8	Confident	93 Å²	93	31.9 Å²	31.9	44%	0.435	16%	0.164	S	C	.	.	S	Bend	trans	-67.9	120.4	-175.1	-67.6	175.6	-15.8	0	0	109	N97 T122 I128	N97-Q124 PolarHBondContact ND2-OE1 2.9Å; T122-Q124 PolarHBondContact O-N 2.85Å; Q124-I128 HydrophobicContact CB-CD1 4.39Å; Q124-I128 VanDerWaalsContact O-CB 3.29Å; Q124-I128 WeakPolarHBondContact O-CB 3.37Å; Q124-I128 WeakPolarHBondContact O-CD1 3.4Å
125	S	73.9	Confident	83.1	Confident	66 Å²	66	32.8 Å²	32.8	46%	0.462	17%	0.169	S	C	.	.	H	α-helix	trans	68.5	157.2	-173.1	83.5	0	0	0	0	115.9	F123 H127 I128 R129	F123-S125 PolarHBondContact O-N 3.46Å; S125-H127 VanDerWaalsContact C-N 3.31Å; S125-H127 PolarHBondContact OG-N 2.87Å; S125-I128 PolarHBondContact OG-N 3.33Å; S125-R129 PolarHBondContact O-N 3.36Å; S125-R129 PolarHBondContact O-NH1 3.42Å
126	S	80.3	Confident	83.5	Confident	34 Å²	34	32.8 Å²	32.8	24%	0.238	17%	0.169	C	C	.	.	H	α-helix	trans	-66	-32.9	170.2	49.1	0	0	0	0	112.9	R129 R130 D224	S126-R129 PolarHBondContact O-N 2.89Å; S126-R130 WeakPolarHBondContact O-CB 3.42Å; S126-R130 PolarHBondContact O-N 3.15Å; S126-D224 WeakPolarHBondContact CB-OD2 3.14Å; S126-D224 PolarHBondContact OG-OD2 2.67Å
127	H	79.8	Confident	84.2	Confident	65 Å²	65	30.5 Å²	30.5	30%	0.301	15%	0.153	S	C	.	.	H	α-helix	trans	-58.7	-53.6	-179.3	-174.7	82.4	0	0	0	111.5	E98 S125 R130 K131 Y225	E98-H127 IonicContact OE1-CD2 3.41Å; E98-H127 PolarHBondContact OE1-CD2 3.25Å; E98-H127 IonicContact OE1-NE2 3.69Å; E98-H127 PolarHBondContact OE1-NE2 3.33Å; S125-H127 VanDerWaalsContact C-N 3.31Å; S125-H127 PolarHBondContact OG-N 2.87Å; H127-R130 PolarHBondContact O-N 2.89Å; H127-K131 VanDerWaalsContact CE1-CE 3.5Å; H127-K131 WeakPolarHBondContact CE1-CE 3.15Å; H127-K131 WeakPolarHBondContact NE2-CE 3.29Å; H127-K131 PolarHBondContact NE2-NZ 2.77Å; H127-K131 PolarHBondContact O-N 2.96Å; H127-Y225 WeakPolarHBondContact CA-OH 3.35Å; H127-Y225 PolarHBondContact CE1-OH 3.41Å; H127-Y225 VanDerWaalsContact CE1-OH 3.23Å; H127-Y225 AromaticContact ND1-CZ 3.61Å; H127-Y225 PolarHBondContact ND1-OH 3.48Å; H127-Y225 PolarHBondContact O-OH 2.89Å
128	I	82.1	Confident	84.6	Confident	8 Å²	8	29.3 Å²	29.3	4%	0.041	15%	0.152	C	C	.	.	H	α-helix	trans	-67.9	-40.6	-179.1	-65.5	156.6	0	0	0	110.7	N97 I101 Q124 S125 R130 K131 L132	N97-I128 HydrophobicContact CB-CD1 3.34Å; N97-I128 HydrophobicContact CB-CG1 3.94Å; N97-I128 VanDerWaalsContact ND2-CD1 3.29Å; N97-I128 WeakPolarHBondContact ND2-CD1 3.47Å; I101-I128 HydrophobicContact CD1-CB 4.3Å; I101-I128 HydrophobicContact CD1-CG1 3.96Å; I101-I128 HydrophobicContact CD1-CG2 4.2Å; Q124-I128 HydrophobicContact CB-CD1 4.39Å; Q124-I128 VanDerWaalsContact O-CB 3.29Å; Q124-I128 WeakPolarHBondContact O-CB 3.37Å; Q124-I128 WeakPolarHBondContact O-CD1 3.4Å; S125-I128 PolarHBondContact OG-N 3.33Å; I128-R130 PolarHBondContact O-N 3.4Å; I128-K131 PolarHBondContact O-N 3.28Å; I128-L132 HydrophobicContact CG2-CD1 3.66Å; I128-L132 HydrophobicContact CG2-CG 4.08Å; I128-L132 WeakPolarHBondContact O-CB 3.37Å; I128-L132 WeakPolarHBondContact O-CG 3.47Å; I128-L132 PolarHBondContact O-N 3.24Å
129	R	90	Very high	84.3	Confident	17 Å²	17	31.6 Å²	31.6	6%	0.064	17%	0.169	C	C	.	.	H	α-helix	trans	-55.3	-53.5	174.9	178.2	176.1	-63.1	86.2	14.1	111.6	F123 S125 S126 K131 L132 W133 D365	F123-R129 HydrophobicContact CB-CB 4.03Å; F123-R129 HydrophobicContact CD2-CB 4.3Å; F123-R129 HydrophobicContact CD2-CG 4.21Å; F123-R129 PolarHBondContact O-NH2 3.36Å; S125-R129 PolarHBondContact O-N 3.36Å; S125-R129 PolarHBondContact O-NH1 3.42Å; S126-R129 PolarHBondContact O-N 2.89Å; R129-K131 VanDerWaalsContact C-N 3.33Å; R129-K131 PolarHBondContact O-N 3.01Å; R129-L132 PolarHBondContact O-N 2.86Å; R129-W133 HydrophobicContact CG-CD2 4.22Å; R129-W133 HydrophobicContact CG-CG 4.2Å; R129-W133 HydrophobicContact CG-CZ2 4.31Å; R129-W133 VanDerWaalsContact O-CB 3.31Å; R129-W133 WeakPolarHBondContact O-CB 3.29Å; R129-W133 PolarHBondContact O-N 2.91Å; R129-D365 WeakPolarHBondContact CD-OD1 3.26Å; R129-D365 IonicContact CZ-OD1 3.32Å; R129-D365 IonicContact CZ-OD2 2.8Å; R129-D365 IonicContact NE-OD1 3.7Å; R129-D365 PolarHBondContact NE-OD1 3.45Å; R129-D365 IonicContact NE-OD2 3.9Å; R129-D365 PolarHBondContact NE-OD2 3.23Å; R129-D365 IonicContact NH2-OD1 3.36Å; R129-D365 IonicContact NH2-OD2 2.88Å; R129-D365 PolarHBondContact NH2-OD2 3.05Å
130	R	89.8	Confident	83.8	Confident	20 Å²	20	35.5 Å²	35.5	8%	0.075	18%	0.183	C	C	.	.	H	α-helix	trans	-53.9	-51.8	179.3	169	66.8	-163.3	125.9	-6.2	111	S126 H127 I128 W133 S134 M222 Y225 E243	S126-R130 WeakPolarHBondContact O-CB 3.42Å; S126-R130 PolarHBondContact O-N 3.15Å; H127-R130 PolarHBondContact O-N 2.89Å; I128-R130 PolarHBondContact O-N 3.4Å; R130-W133 PolarHBondContact O-N 2.89Å; R130-S134 VanDerWaalsContact O-CB 3.28Å; R130-S134 WeakPolarHBondContact O-CB 3.25Å; R130-S134 PolarHBondContact O-N 3.47Å; R130-M222 VanDerWaalsContact NE-CE 3.3Å; R130-M222 PolarHBondContact NE-SD 2.93Å; R130-M222 PolarHBondContact NH2-SD 3.06Å; R130-Y225 HydrophobicContact CB-CD2 4.05Å; R130-Y225 HydrophobicContact CB-CE2 3.4Å; R130-Y225 VanDerWaalsContact CB-CE2 3.4Å; R130-Y225 HydrophobicContact CG-CD2 3.82Å; R130-Y225 HydrophobicContact CG-CE2 3.47Å; R130-Y225 VanDerWaalsContact CG-CE2 3.47Å; R130-Y225 HydrophobicContact CG-CG 4.48Å; R130-E243 IonicContact CZ-OE1 3.83Å; R130-E243 IonicContact CZ-OE2 3.1Å; R130-E243 IonicContact NH1-OE1 2.8Å; R130-E243 PolarHBondContact NH1-OE1 3.22Å; R130-E243 IonicContact NH1-OE2 2.86Å; R130-E243 PolarHBondContact NH1-OE2 3.04Å; R130-E243 IonicContact NH2-OE1 3.45Å; R130-E243 PolarHBondContact NH2-OE1 3.14Å; R130-E243 IonicContact NH2-OE2 3.71Å; R130-E243 PolarHBondContact NH2-OE2 3.45Å
131	K	87.6	Confident	82.9	Confident	51 Å²	51	35.4 Å²	35.4	22%	0.222	18%	0.183	C	C	.	.	H	α-helix	trans	-64.1	-46.9	-177.1	-73.2	-165.7	-179.2	163.5	0	111.5	E98 I101 H127 I128 R129 S134 I135	E98-K131 IonicContact OE1-NZ 3.27Å; E98-K131 IonicContact OE2-NZ 2.72Å; E98-K131 PolarHBondContact OE2-NZ 3.43Å; I101-K131 HydrophobicContact CD1-CB 4.12Å; I101-K131 HydrophobicContact CD1-CD 3.95Å; I101-K131 HydrophobicContact CG1-CB 4.2Å; I101-K131 HydrophobicContact CG1-CD 4.42Å; I101-K131 HydrophobicContact CG2-CB 4.16Å; I101-K131 HydrophobicContact CG2-CD 3.5Å; I101-K131 VanDerWaalsContact CG2-CD 3.5Å; I101-K131 HydrophobicContact CG2-CG 4.48Å; H127-K131 VanDerWaalsContact CE1-CE 3.5Å; H127-K131 WeakPolarHBondContact CE1-CE 3.15Å; H127-K131 WeakPolarHBondContact NE2-CE 3.29Å; H127-K131 PolarHBondContact NE2-NZ 2.77Å; H127-K131 PolarHBondContact O-N 2.96Å; I128-K131 PolarHBondContact O-N 3.28Å; R129-K131 VanDerWaalsContact C-N 3.33Å; R129-K131 PolarHBondContact O-N 3.01Å; K131-S134 PolarHBondContact O-N 3.26Å; K131-I135 WeakPolarHBondContact O-CD1 3.48Å; K131-I135 WeakPolarHBondContact O-CG1 3.38Å; K131-I135 PolarHBondContact O-N 3.42Å
132	L	88.3	Confident	81.5	Confident	1 Å²	1	38 Å²	38	1%	0.005	19%	0.193	C	C	.	.	H	α-helix	trans	-63.1	-45.6	177.7	-72	179.4	0	0	0	112.1	I101 F104 L114 Y118 F123 I128 R129 S134 I135 I136	I101-L132 HydrophobicContact CG1-CD2 4.3Å; F104-L132 HydrophobicContact CD2-CD2 4.11Å; L114-L132 HydrophobicContact CD1-CD2 4.45Å; L114-L132 HydrophobicContact CD2-CD2 3.91Å; Y118-L132 HydrophobicContact CE2-CD1 4.15Å; F123-L132 HydrophobicContact CD1-CD1 3.72Å; F123-L132 HydrophobicContact CD2-CD1 4.32Å; F123-L132 HydrophobicContact CE1-CD1 3.75Å; F123-L132 HydrophobicContact CE2-CB 4.32Å; F123-L132 HydrophobicContact CE2-CD1 4.36Å; F123-L132 HydrophobicContact CG-CD1 4.03Å; F123-L132 HydrophobicContact CZ-CD1 4.09Å; I128-L132 HydrophobicContact CG2-CD1 3.66Å; I128-L132 HydrophobicContact CG2-CG 4.08Å; I128-L132 WeakPolarHBondContact O-CB 3.37Å; I128-L132 WeakPolarHBondContact O-CG 3.47Å; I128-L132 PolarHBondContact O-N 3.24Å; R129-L132 PolarHBondContact O-N 2.86Å; L132-S134 VanDerWaalsContact C-N 3.31Å; L132-S134 PolarHBondContact O-N 3.17Å; L132-I135 PolarHBondContact O-N 2.98Å; L132-I136 VanDerWaalsContact O-CB 3.3Å; L132-I136 WeakPolarHBondContact O-CB 3.24Å; L132-I136 WeakPolarHBondContact O-CD1 3.41Å; L132-I136 WeakPolarHBondContact O-CG1 3.32Å; L132-I136 PolarHBondContact O-N 3.35Å
133	W	91.3	Very high	79.9	Confident	1 Å²	1	41.9 Å²	41.9	0%	0.004	22%	0.222	C	C	.	.	H	α-helix	trans	-58.9	-44.8	175.2	-77.5	32.6	0	0	0	111.1	F123 R129 R130 I136 L137 I217 A221 L361 W364 D365 M368	F123-W133 AromaticContact CD2-CD1 3.95Å; F123-W133 AromaticContact CD2-NE1 3.8Å; F123-W133 AromaticContact CE2-CD1 3.72Å; F123-W133 AromaticContact CE2-NE1 3.69Å; R129-W133 HydrophobicContact CG-CD2 4.22Å; R129-W133 HydrophobicContact CG-CG 4.2Å; R129-W133 HydrophobicContact CG-CZ2 4.31Å; R129-W133 VanDerWaalsContact O-CB 3.31Å; R129-W133 WeakPolarHBondContact O-CB 3.29Å; R129-W133 PolarHBondContact O-N 2.91Å; R130-W133 PolarHBondContact O-N 2.89Å; W133-I136 PolarHBondContact O-N 2.89Å; W133-L137 WeakPolarHBondContact O-CB 3.49Å; W133-L137 WeakPolarHBondContact O-CG 3.48Å; W133-L137 PolarHBondContact O-N 3.47Å; W133-I217 HydrophobicContact CH2-CD1 4.28Å; W133-I217 HydrophobicContact CH2-CG1 4.07Å; W133-I217 HydrophobicContact CZ3-CG1 4.39Å; W133-A221 HydrophobicContact CD2-CB 4.05Å; W133-A221 HydrophobicContact CE3-CB 3.44Å; W133-A221 VanDerWaalsContact CE3-CB 3.44Å; W133-A221 HydrophobicContact CH2-CB 3.95Å; W133-A221 HydrophobicContact CZ2-CB 4.48Å; W133-A221 HydrophobicContact CZ3-CB 3.4Å; W133-A221 VanDerWaalsContact CZ3-CB 3.4Å; W133-L361 HydrophobicContact CH2-CD2 4.32Å; W133-W364 HydrophobicContact CH2-CB 3.66Å; W133-W364 HydrophobicContact CH2-CE3 4.36Å; W133-W364 HydrophobicContact CH2-CG 4.31Å; W133-W364 HydrophobicContact CZ2-CB 3.64Å; W133-D365 PolarHBondContact NE1-OD1 3.36Å; W133-M368 HydrophobicContact CD2-CE 3.96Å; W133-M368 HydrophobicContact CD2-CG 3.85Å; W133-M368 HydrophobicContact CD2-SD 4.3Å; W133-M368 HydrophobicContact CE3-CE 3.73Å; W133-M368 HydrophobicContact CG-CG 3.95Å; W133-M368 HydrophobicContact CG-SD 4.34Å; W133-M368 HydrophobicContact CH2-CE 4.44Å; W133-M368 HydrophobicContact CZ2-CG 4.25Å; W133-M368 HydrophobicContact CZ3-CE 3.98Å
134	S	89.3	Confident	78.3	Confident	19 Å²	19	43.3 Å²	43.3	13%	0.133	23%	0.229	C	C	.	.	H	α-helix	trans	-59.6	-50.4	177.1	-164.7	0	0	0	0	111.4	R130 K131 L132 I136 L137 L138 E243	R130-S134 VanDerWaalsContact O-CB 3.28Å; R130-S134 WeakPolarHBondContact O-CB 3.25Å; R130-S134 PolarHBondContact O-N 3.47Å; K131-S134 PolarHBondContact O-N 3.26Å; L132-S134 VanDerWaalsContact C-N 3.31Å; L132-S134 PolarHBondContact O-N 3.17Å; S134-I136 VanDerWaalsContact C-N 3.34Å; S134-I136 PolarHBondContact O-N 3.42Å; S134-L137 PolarHBondContact O-N 3.19Å; S134-L138 WeakPolarHBondContact O-CB 3.29Å; S134-L138 WeakPolarHBondContact O-CG 3.28Å; S134-L138 PolarHBondContact O-N 3.37Å; S134-L138 WeakPolarHBondContact OG-CD1 3.42Å; S134-E243 WeakPolarHBondContact CA-OE1 3.32Å; S134-E243 VanDerWaalsContact CB-OE1 3.24Å; S134-E243 WeakPolarHBondContact CB-OE1 3.5Å; S134-E243 PolarHBondContact OG-OE1 3.35Å
135	I	86.2	Confident	77.4	Confident	20 Å²	20	40.2 Å²	40.2	10%	0.103	22%	0.221	C	C	.	.	H	α-helix	trans	-61.1	-43.8	178.3	-61	159.3	0	0	0	110.7	I101 F104 E105 L111 K131 L132 S139	I101-I135 HydrophobicContact CG2-CD1 4.23Å; F104-I135 HydrophobicContact CB-CD1 4.32Å; F104-I135 HydrophobicContact CB-CG2 4.09Å; E105-I135 HydrophobicContact CG-CD1 3.62Å; E105-I135 HydrophobicContact CG-CG1 3.88Å; L111-I135 HydrophobicContact CD1-CG2 4.11Å; L111-I135 HydrophobicContact CD2-CG2 3.74Å; L111-I135 HydrophobicContact CG-CG2 4.43Å; K131-I135 WeakPolarHBondContact O-CD1 3.48Å; K131-I135 WeakPolarHBondContact O-CG1 3.38Å; K131-I135 PolarHBondContact O-N 3.42Å; L132-I135 PolarHBondContact O-N 2.98Å; I135-S139 WeakPolarHBondContact O-CB 3.21Å; I135-S139 PolarHBondContact O-N 3.09Å; I135-S139 PolarHBondContact O-OG 3.33Å
136	I	87	Confident	76.5	Confident	0 Å²	0	41.8 Å²	41.8	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-58.6	-54.4	178	-74.4	165.5	0	0	0	110.9	L114 L132 W133 S134 S139 M368 I371 V372	L114-I136 HydrophobicContact CD1-CD1 4.08Å; L114-I136 HydrophobicContact CD1-CG1 4Å; L132-I136 VanDerWaalsContact O-CB 3.3Å; L132-I136 WeakPolarHBondContact O-CB 3.24Å; L132-I136 WeakPolarHBondContact O-CD1 3.41Å; L132-I136 WeakPolarHBondContact O-CG1 3.32Å; L132-I136 PolarHBondContact O-N 3.35Å; W133-I136 PolarHBondContact O-N 2.89Å; S134-I136 VanDerWaalsContact C-N 3.34Å; S134-I136 PolarHBondContact O-N 3.42Å; I136-S139 PolarHBondContact O-N 2.89Å; I136-S139 PolarHBondContact O-OG 3.46Å; I136-M368 HydrophobicContact CD1-CB 3.96Å; I136-M368 HydrophobicContact CG2-SD 4.23Å; I136-I371 HydrophobicContact CG2-CB 4.1Å; I136-I371 HydrophobicContact CG2-CG2 3.95Å; I136-V372 HydrophobicContact CB-CG1 4.04Å; I136-V372 HydrophobicContact CD1-CG2 4.35Å; I136-V372 HydrophobicContact CG1-CG1 3.74Å; I136-V372 HydrophobicContact CG1-CG2 4.18Å; I136-V372 HydrophobicContact CG2-CG1 3.76Å
137	L	86.3	Confident	75.6	Confident	0 Å²	0	43.6 Å²	43.6	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-69.9	-45	-176.1	-66.7	171.2	0	0	0	111	W133 S134 S139 R140 L218 E243 V246 L247 M368 I371	W133-L137 WeakPolarHBondContact O-CB 3.49Å; W133-L137 WeakPolarHBondContact O-CG 3.48Å; W133-L137 PolarHBondContact O-N 3.47Å; S134-L137 PolarHBondContact O-N 3.19Å; L137-S139 VanDerWaalsContact C-N 3.29Å; L137-S139 PolarHBondContact O-N 2.97Å; L137-R140 WeakPolarHBondContact O-CB 3.25Å; L137-R140 PolarHBondContact O-N 3.23Å; L137-R140 VanDerWaalsContact O-N 3.08Å; L137-L218 HydrophobicContact CD1-CD1 3.96Å; L137-E243 HydrophobicContact CB-CB 4.23Å; L137-E243 HydrophobicContact CB-CG 3.99Å; L137-E243 HydrophobicContact CD1-CB 3.81Å; L137-E243 HydrophobicContact CD1-CG 4.16Å; L137-V246 HydrophobicContact CB-CG1 4.28Å; L137-V246 HydrophobicContact CD2-CG1 3.95Å; L137-V246 WeakPolarHBondContact O-CG1 3.38Å; L137-L247 HydrophobicContact CD2-CB 4.28Å; L137-L247 HydrophobicContact CD2-CD1 4.45Å; L137-M368 HydrophobicContact CD1-CE 4.12Å; L137-M368 HydrophobicContact CD1-SD 4.34Å; L137-M368 HydrophobicContact CD2-CE 4.28Å; L137-M368 HydrophobicContact CD2-SD 4.01Å; L137-M368 HydrophobicContact CG-CE 4.46Å; L137-M368 HydrophobicContact CG-SD 4.1Å; L137-I371 HydrophobicContact CD2-CD1 4.35Å
138	L	81.9	Confident	74.9	Confident	51 Å²	51	40.6 Å²	40.6	27%	0.267	22%	0.218	S	C	.	.	H	α-helix	trans	-68.4	-27.3	179.2	-63.9	177.8	0	0	0	112.6	S134 R140 C141 V239 Q242 E243	S134-L138 WeakPolarHBondContact O-CB 3.29Å; S134-L138 WeakPolarHBondContact O-CG 3.28Å; S134-L138 PolarHBondContact O-N 3.37Å; S134-L138 WeakPolarHBondContact OG-CD1 3.42Å; L138-R140 PolarHBondContact O-N 3.49Å; L138-R140 VanDerWaalsContact O-N 3.13Å; L138-C141 PolarHBondContact O-N 3.45Å; L138-V239 HydrophobicContact CD1-CG1 4.15Å; L138-Q242 HydrophobicContact CD2-CB 4Å; L138-E243 HydrophobicContact CD2-CG 3.96Å; L138-E243 HydrophobicContact CG-CG 4.16Å
139	S	78.2	Confident	74.1	Confident	53 Å²	53	43.2 Å²	43.2	37%	0.371	23%	0.23	S	C	.	.	H	α-helix	trans	-60.6	-22.3	172.5	75.8	0	0	0	0	113.3	L111 I135 I136 L137	L111-S139 WeakPolarHBondContact CD1-OG 3.18Å; I135-S139 WeakPolarHBondContact O-CB 3.21Å; I135-S139 PolarHBondContact O-N 3.09Å; I135-S139 PolarHBondContact O-OG 3.33Å; I136-S139 PolarHBondContact O-N 2.89Å; I136-S139 PolarHBondContact O-OG 3.46Å; L137-S139 VanDerWaalsContact C-N 3.29Å; L137-S139 PolarHBondContact O-N 2.97Å
140	R	74.4	Confident	73.1	Confident	103 Å²	103	48.4 Å²	48.4	39%	0.389	26%	0.255	S	S	.	.	H	α-helix	trans	-89.7	-14.7	176.2	-61.4	-72.3	177.4	-177.7	-15.1	112.8	L137 L138 V246 I250 I371	L137-R140 WeakPolarHBondContact O-CB 3.25Å; L137-R140 PolarHBondContact O-N 3.23Å; L137-R140 VanDerWaalsContact O-N 3.08Å; L138-R140 PolarHBondContact O-N 3.49Å; L138-R140 VanDerWaalsContact O-N 3.13Å; R140-V246 HydrophobicContact CB-CG1 3.71Å; R140-V246 HydrophobicContact CG-CG1 4.4Å; R140-I250 HydrophobicContact CB-CD1 4.15Å; R140-I250 HydrophobicContact CG-CD1 3.86Å; R140-I371 HydrophobicContact CG-CG2 4.24Å; R140-I371 VanDerWaalsContact CZ-O 3.23Å; R140-I371 PolarHBondContact NE-O 3.18Å; R140-I371 PolarHBondContact NH2-O 2.67Å
141	C	68.3	Low	72.1	Confident	18 Å²	18	49.9 Å²	49.9	12%	0.122	26%	0.264	C	S	.	.	S	Bend	trans	-97.2	123.9	175.9	-164.2	0	0	0	0	110	L138 S143 V246	L138-C141 PolarHBondContact O-N 3.45Å; C141-S143 PolarHBondContact O-N 3.4Å; C141-V246 HydrophobicContact CB-CG2 3.75Å
142	K	55.3	Low	71.3	Confident	144 Å²	144	47.8 Å²	47.8	63%	0.626	26%	0.255	S	S	*	.			trans	-70.3	116.2	161.5	-67.2	-174.3	-177.9	178.7	0	107.1	Q144	K142-Q144 PolarHBondContact O-N 2.84Å
143	S	52	Low	70.5	Confident	113 Å²	113	54.3 Å²	54.3	79%	0.79	29%	0.285	S	S	*	.			trans	-42.9	120.2	-171.9	50.5	0	0	0	0	113.7	C141	C141-S143 PolarHBondContact O-N 3.4Å
144	Q	52.1	Low	69.6	Low	33 Å²	33	59.1 Å²	59.1	15%	0.154	32%	0.315	C	S	.	.			trans	-135.4	31.8	170	-63.5	-156.2	40.7	0	0	112.7	K142 T146 K147 F148 I272	K142-Q144 PolarHBondContact O-N 2.84Å; Q144-T146 VanDerWaalsContact C-N 3.25Å; Q144-T146 PolarHBondContact O-N 2.72Å; Q144-T146 VanDerWaalsContact O-N 3.07Å; Q144-K147 PolarHBondContact O-N 3.27Å; Q144-F148 HydrophobicContact CB-CE2 4.42Å; Q144-I272 HydrophobicContact CB-CG2 4.39Å
145	G	52.1	Low	68.7	Low	27 Å²	27	59.7 Å²	59.7	28%	0.278	32%	0.315	S	S	.	.	H	α-helix	trans	-35.4	-53.9	179.9	0	0	0	0	0	114.5	K147 F148 E149	G145-K147 VanDerWaalsContact C-N 3.29Å; G145-K147 PolarHBondContact O-N 3.37Å; G145-F148 PolarHBondContact O-N 3Å; G145-E149 WeakPolarHBondContact O-CG 3.44Å; G145-E149 PolarHBondContact O-N 3.16Å
146	T	54.6	Low	67.6	Low	99 Å²	99	60.8 Å²	60.8	61%	0.607	33%	0.325	S	S	*	.	H	α-helix	trans	-61.5	-29.6	-172.5	53.1	0	0	0	0	114.7	Q144 Q150	Q144-T146 VanDerWaalsContact C-N 3.25Å; Q144-T146 PolarHBondContact O-N 2.72Å; Q144-T146 VanDerWaalsContact O-N 3.07Å; T146-Q150 WeakPolarHBondContact O-CG 3.33Å; T146-Q150 PolarHBondContact O-N 2.8Å
147	K	61.3	Low	66.2	Low	73 Å²	73	63.6 Å²	63.6	32%	0.317	34%	0.343	S	S	.	.	H	α-helix	trans	-82.1	-35.8	-179	-73.2	-175.4	174.8	-173	0	113	Q144 G145 E149 Q150 I151 I272	Q144-K147 PolarHBondContact O-N 3.27Å; G145-K147 VanDerWaalsContact C-N 3.29Å; G145-K147 PolarHBondContact O-N 3.37Å; K147-E149 VanDerWaalsContact C-N 3.32Å; K147-Q150 PolarHBondContact O-N 2.93Å; K147-I151 PolarHBondContact O-N 3.19Å; K147-I272 HydrophobicContact CB-CG2 3.95Å; K147-I272 HydrophobicContact CD-CG2 3.51Å; K147-I272 HydrophobicContact CG-CG2 4.43Å; K147-I272 PolarHBondContact NZ-O 3.46Å
148	F	65.2	Low	64.9	Low	2 Å²	2	69.6 Å²	69.6	1%	0.009	38%	0.375	C	S	.	.	H	α-helix	trans	-63.8	-43.4	174.8	-76.3	-92.1	0	0	0	110.3	Q144 G145 Q150 I151 I152 F196 Q242 I272	Q144-F148 HydrophobicContact CB-CE2 4.42Å; G145-F148 PolarHBondContact O-N 3Å; F148-Q150 VanDerWaalsContact C-N 3.31Å; F148-Q150 PolarHBondContact O-N 2.62Å; F148-I151 PolarHBondContact O-N 2.84Å; F148-I152 HydrophobicContact CB-CD1 4.23Å; F148-I152 WeakPolarHBondContact O-CB 3.38Å; F148-I152 VanDerWaalsContact O-CD1 3.29Å; F148-I152 WeakPolarHBondContact O-CD1 3.05Å; F148-I152 WeakPolarHBondContact O-CG1 3.47Å; F148-I152 PolarHBondContact O-N 3.36Å; F148-F196 AromaticContact CD1-CE1 3.65Å; F148-F196 HydrophobicContact CD1-CE1 3.65Å; F148-F196 AromaticContact CD1-CE2 3.75Å; F148-F196 HydrophobicContact CD1-CE2 3.75Å; F148-F196 AromaticContact CD1-CZ 3.15Å; F148-F196 HydrophobicContact CD1-CZ 3.15Å; F148-F196 HydrophobicContact CE1-CD1 4.49Å; F148-F196 AromaticContact CE1-CE1 3.36Å; F148-F196 HydrophobicContact CE1-CE1 3.36Å; F148-F196 HydrophobicContact CE1-CE2 4.25Å; F148-F196 AromaticContact CE1-CZ 3.22Å; F148-F196 HydrophobicContact CE1-CZ 3.22Å; F148-F196 HydrophobicContact CG-CZ 4.3Å; F148-F196 HydrophobicContact CZ-CZ 4.39Å; F148-Q242 HydrophobicContact CD1-CG 4.47Å; F148-Q242 HydrophobicContact CD2-CG 3.68Å; F148-Q242 HydrophobicContact CE1-CG 4.34Å; F148-Q242 HydrophobicContact CE2-CG 3.53Å; F148-Q242 HydrophobicContact CG-CG 4.15Å; F148-Q242 HydrophobicContact CZ-CG 3.89Å; F148-I272 HydrophobicContact CE2-CD1 3.52Å; F148-I272 HydrophobicContact CE2-CG1 4.13Å; F148-I272 HydrophobicContact CZ-CD1 3.52Å; F148-I272 HydrophobicContact CZ-CG1 3.98Å
149	E	65.8	Low	63.7	Low	63 Å²	63	73 Å²	73	29%	0.294	39%	0.389	S	S	.	.	H	α-helix	trans	-56.8	-43.3	178.2	-70.6	168.3	-169	0	0	112.4	G145 K147 I151 I152 Q153 V234	G145-E149 WeakPolarHBondContact O-CG 3.44Å; G145-E149 PolarHBondContact O-N 3.16Å; K147-E149 VanDerWaalsContact C-N 3.32Å; E149-I151 PolarHBondContact O-N 3.41Å; E149-I152 PolarHBondContact O-N 2.94Å; E149-Q153 VanDerWaalsContact O-CG 3.27Å; E149-Q153 WeakPolarHBondContact O-CG 3.34Å; E149-Q153 PolarHBondContact O-N 3.47Å; E149-V234 HydrophobicContact CB-CG1 4.27Å; E149-V234 HydrophobicContact CG-CG1 4.32Å
150	Q	68.5	Low	63.1	Low	125 Å²	125	74.2 Å²	74.2	58%	0.584	39%	0.392	S	S	*	.	H	α-helix	trans	-61.1	-44.7	177.3	-73.7	175.3	-11	0	0	112.3	T146 K147 F148	T146-Q150 WeakPolarHBondContact O-CG 3.33Å; T146-Q150 PolarHBondContact O-N 2.8Å; K147-Q150 PolarHBondContact O-N 2.93Å; F148-Q150 VanDerWaalsContact C-N 3.31Å; F148-Q150 PolarHBondContact O-N 2.62Å
151	I	69.5	Low	63.2	Low	52 Å²	52	76.5 Å²	76.5	27%	0.267	41%	0.407	S	S	.	.	H	α-helix	trans	-66.2	-44.7	177.5	-64.5	169.4	0	0	0	110.3	K147 F148 E149 Q153 T154 F155 F196 M199	K147-I151 PolarHBondContact O-N 3.19Å; F148-I151 PolarHBondContact O-N 2.84Å; E149-I151 PolarHBondContact O-N 3.41Å; I151-Q153 VanDerWaalsContact C-N 3.25Å; I151-Q153 PolarHBondContact O-N 3.28Å; I151-T154 WeakPolarHBondContact O-CB 3.27Å; I151-T154 PolarHBondContact O-N 2.89Å; I151-T154 PolarHBondContact O-OG1 3.49Å; I151-F155 HydrophobicContact CG2-CE2 4.27Å; I151-F155 HydrophobicContact CG2-CZ 3.92Å; I151-F196 HydrophobicContact CB-CE2 3.97Å; I151-F196 HydrophobicContact CD1-CE2 4.01Å; I151-F196 HydrophobicContact CD1-CZ 4.44Å; I151-F196 HydrophobicContact CG2-CD2 3.77Å; I151-F196 HydrophobicContact CG2-CE2 3.57Å; I151-M199 HydrophobicContact CD1-CE 4.45Å; I151-M199 HydrophobicContact CG2-CE 3.33Å; I151-M199 HydrophobicContact CG2-SD 3.74Å
152	I	70.6	Confident	64	Low	7 Å²	7	80 Å²	80	4%	0.036	42%	0.421	C	S	.	.	H	α-helix	trans	-61.4	-36.9	-178	-68.7	157.3	0	0	0	111.3	F148 E149 T154 F155 F196 V234 I237 G238	F148-I152 HydrophobicContact CB-CD1 4.23Å; F148-I152 WeakPolarHBondContact O-CB 3.38Å; F148-I152 VanDerWaalsContact O-CD1 3.29Å; F148-I152 WeakPolarHBondContact O-CD1 3.05Å; F148-I152 WeakPolarHBondContact O-CG1 3.47Å; F148-I152 PolarHBondContact O-N 3.36Å; E149-I152 PolarHBondContact O-N 2.94Å; I152-T154 PolarHBondContact O-N 2.95Å; I152-F155 HydrophobicContact CB-CD2 4.48Å; I152-F155 HydrophobicContact CG1-CE2 4.39Å; I152-F155 WeakPolarHBondContact O-CB 3.39Å; I152-F155 PolarHBondContact O-N 2.98Å; I152-F196 HydrophobicContact CG1-CD2 4.49Å; I152-V234 HydrophobicContact CB-CG1 4.37Å; I152-V234 HydrophobicContact CG2-CG1 4.05Å; I152-I237 HydrophobicContact CD1-CB 4.25Å; I152-I237 HydrophobicContact CD1-CG2 3.65Å; I152-I237 HydrophobicContact CG1-CG2 3.97Å; I152-I237 HydrophobicContact CG2-CB 4.29Å; I152-I237 HydrophobicContact CG2-CG2 3.83Å; I152-G238 VanDerWaalsContact CD1-CA 3.46Å
153	Q	71.1	Confident	65.5	Low	138 Å²	138	73.3 Å²	73.3	65%	0.645	39%	0.392	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.8	-20.5	175.6	-73.8	172.7	11.6	0	0	113.4	E149 I151 V234	E149-Q153 VanDerWaalsContact O-CG 3.27Å; E149-Q153 WeakPolarHBondContact O-CG 3.34Å; E149-Q153 PolarHBondContact O-N 3.47Å; I151-Q153 VanDerWaalsContact C-N 3.25Å; I151-Q153 PolarHBondContact O-N 3.28Å; Q153-V234 HydrophobicContact CG-CG1 4.16Å
154	T	72.9	Confident	67.3	Low	102 Å²	102	69.4 Å²	69.4	63%	0.626	36%	0.362	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.9	-16.2	174.8	71.4	0	0	0	0	113.3	I151 I152 S156	I151-T154 WeakPolarHBondContact O-CB 3.27Å; I151-T154 PolarHBondContact O-N 2.89Å; I151-T154 PolarHBondContact O-OG1 3.49Å; I152-T154 PolarHBondContact O-N 2.95Å; T154-S156 PolarHBondContact O-N 3.27Å
155	F	70	Confident	69.1	Low	31 Å²	31	72 Å²	72	14%	0.136	38%	0.38	C	S	.	.			trans	-75.1	119.2	178.3	-63.5	-42.2	0	0	0	110.9	I151 I152 Y192 F196 M199	I151-F155 HydrophobicContact CG2-CE2 4.27Å; I151-F155 HydrophobicContact CG2-CZ 3.92Å; I152-F155 HydrophobicContact CB-CD2 4.48Å; I152-F155 HydrophobicContact CG1-CE2 4.39Å; I152-F155 WeakPolarHBondContact O-CB 3.39Å; I152-F155 PolarHBondContact O-N 2.98Å; F155-Y192 HydrophobicContact CB-CD1 4.37Å; F155-Y192 HydrophobicContact CB-CE1 4.19Å; F155-Y192 HydrophobicContact CD2-CD1 4.29Å; F155-F196 HydrophobicContact CE2-CB 3.8Å; F155-F196 AromaticContact CE2-CD2 3.72Å; F155-F196 HydrophobicContact CE2-CD2 3.72Å; F155-F196 HydrophobicContact CE2-CG 4.23Å; F155-F196 HydrophobicContact CZ-CB 4.01Å; F155-F196 AromaticContact CZ-CD2 3.86Å; F155-F196 HydrophobicContact CZ-CD2 3.86Å; F155-F196 HydrophobicContact CZ-CG 4.36Å; F155-M199 HydrophobicContact CE1-CB 4.39Å; F155-M199 HydrophobicContact CE1-CG 4.46Å; F155-M199 HydrophobicContact CE1-SD 3.65Å; F155-M199 HydrophobicContact CZ-CB 4.41Å; F155-M199 HydrophobicContact CZ-CE 4.25Å; F155-M199 HydrophobicContact CZ-SD 3.73Å
156	S	62.4	Low	71	Confident	43 Å²	43	72.8 Å²	72.8	30%	0.301	38%	0.377	S	S	.	.			trans	-73.7	133.4	165.1	-178.9	0	0	0	0	109.8	T154 D158 Q159 K195	T154-S156 PolarHBondContact O-N 3.27Å; S156-D158 PolarHBondContact O-N 3.41Å; S156-D158 PolarHBondContact OG-N 3.05Å; S156-Q159 PolarHBondContact O-N 2.68Å; S156-K195 PolarHBondContact O-NZ 2.81Å
157	P	58.6	Low	72.8	Confident	58 Å²	58	68 Å²	68	38%	0.377	35%	0.348	S	S	.	.	T	Hydrogen-bonded Turn	trans	-59	-28.5	174.3	21.5	-29.9	0	0	0	112.2	Y188 K195	P157-Y188 HydrophobicContact CB-CE1 4.35Å; P157-K195 PolarHBondContact O-NZ 3.14Å
158	D	57.9	Low	74.3	Confident	127 Å²	127	70.9 Å²	70.9	68%	0.679	36%	0.356	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.9	-9	-172.3	-54.7	-31.9	0	0	0	114	S156	S156-D158 PolarHBondContact O-N 3.41Å; S156-D158 PolarHBondContact OG-N 3.05Å
159	Q	57.6	Low	75.6	Confident	122 Å²	122	74.9 Å²	74.9	57%	0.57	38%	0.381	S	S	*	.	S	Bend	trans	-77.7	151.2	171.2	-73.1	-179.4	-22	0	0	110.3	S156 K195	S156-Q159 PolarHBondContact O-N 2.68Å; Q159-K195 WeakPolarHBondContact O-CE 3.39Å; Q159-K195 PolarHBondContact O-NZ 3.16Å
160	D	65.7	Low	76.9	Confident	78 Å²	78	72.3 Å²	72.3	42%	0.417	37%	0.369	S	S	.	.			trans	58.7	49.3	179.2	-41.8	-49.1	0	0	0	116	H162 I163 K195	D160-H162 PolarHBondContact O-N 3.13Å; D160-I163 HydrophobicContact CB-CD1 3.66Å; D160-I163 HydrophobicContact CB-CG1 4.07Å; D160-I163 PolarHBondContact O-N 2.96Å; D160-I163 VanDerWaalsContact O-N 3.09Å; D160-K195 WeakPolarHBondContact OD2-CE 3.45Å
161	E	75	Confident	78	Confident	151 Å²	151	66.5 Å²	66.5	71%	0.706	34%	0.342	S	S	*	.	H	α-helix	trans	-48.7	-30.3	170.6	-74	-168.6	153.5	0	0	112.8	I163 L164 V165	E161-I163 PolarHBondContact O-N 3.08Å; E161-L164 WeakPolarHBondContact O-CB 3.47Å; E161-L164 PolarHBondContact O-N 3.5Å; E161-V165 VanDerWaalsContact O-CG2 3.27Å; E161-V165 WeakPolarHBondContact O-CG2 3.31Å; E161-V165 PolarHBondContact O-N 2.83Å
162	H	85.6	Confident	79	Confident	91 Å²	91	67.8 Å²	67.8	42%	0.421	35%	0.349	S	S	.	.	H	α-helix	trans	-58.1	-47.8	177.8	-176.8	-89.9	0	0	0	113.2	D160 L164 V165 E166 N206	D160-H162 PolarHBondContact O-N 3.13Å; H162-L164 VanDerWaalsContact C-N 3.3Å; H162-L164 PolarHBondContact O-N 3.36Å; H162-V165 PolarHBondContact O-N 2.88Å; H162-E166 IonicContact CE1-OE1 3.52Å; H162-E166 PolarHBondContact CE1-OE1 3.09Å; H162-E166 IonicContact CE1-OE2 2.95Å; H162-E166 IonicContact ND1-OE1 2.63Å; H162-E166 IonicContact ND1-OE2 3.21Å; H162-E166 IonicContact NE2-OE1 3.74Å; H162-E166 WeakPolarHBondContact O-CG 3.42Å; H162-E166 PolarHBondContact O-N 3.26Å; H162-N206 PolarHBondContact CE1-OD1 2.78Å
163	I	88	Confident	79.9	Confident	4 Å²	4	71.7 Å²	71.7	2%	0.021	38%	0.377	C	S	.	.	H	α-helix	trans	-63	-42.5	-179.7	-58.7	168.9	0	0	0	109.9	D160 E161 V165 E166 C167 N191 L194 K195 Q198 I207	D160-I163 HydrophobicContact CB-CD1 3.66Å; D160-I163 HydrophobicContact CB-CG1 4.07Å; D160-I163 PolarHBondContact O-N 2.96Å; D160-I163 VanDerWaalsContact O-N 3.09Å; E161-I163 PolarHBondContact O-N 3.08Å; I163-V165 VanDerWaalsContact C-N 3.32Å; I163-V165 PolarHBondContact O-N 3.26Å; I163-E166 PolarHBondContact O-N 2.84Å; I163-C167 WeakPolarHBondContact O-CB 3.42Å; I163-C167 PolarHBondContact O-N 3.39Å; I163-C167 PolarHBondContact O-SG 3.49Å; I163-N191 WeakPolarHBondContact CG2-OD1 3.5Å; I163-L194 HydrophobicContact CG2-CB 3.83Å; I163-L194 HydrophobicContact CG2-CD1 4.03Å; I163-K195 HydrophobicContact CD1-CG 3.64Å; I163-Q198 VanDerWaalsContact CD1-OE1 3.26Å; I163-I207 HydrophobicContact CB-CD1 4.49Å; I163-I207 HydrophobicContact CD1-CD1 3.72Å; I163-I207 HydrophobicContact CG1-CD1 3.73Å; I163-I207 HydrophobicContact CG1-CG1 4.44Å; I163-I207 HydrophobicContact CG2-CD1 3.98Å
164	L	89.2	Confident	80.8	Confident	32 Å²	32	65.3 Å²	65.3	17%	0.168	35%	0.348	C	S	.	.	H	α-helix	trans	-61.1	-42.3	177.6	-166	90	0	0	0	111.2	E161 H162 R168 L187 Y188 N191	E161-L164 WeakPolarHBondContact O-CB 3.47Å; E161-L164 PolarHBondContact O-N 3.5Å; H162-L164 VanDerWaalsContact C-N 3.3Å; H162-L164 PolarHBondContact O-N 3.36Å; L164-R168 WeakPolarHBondContact O-CB 3.41Å; L164-R168 PolarHBondContact O-N 3.01Å; L164-L187 HydrophobicContact CD1-CD1 4.47Å; L164-L187 HydrophobicContact CD1-CD2 4.16Å; L164-L187 HydrophobicContact CD1-CG 3.96Å; L164-L187 HydrophobicContact CG-CD2 4.27Å; L164-L187 HydrophobicContact CG-CG 4.41Å; L164-Y188 HydrophobicContact CD1-CE1 4.49Å; L164-N191 HydrophobicContact CD1-CB 3.93Å
165	V	90.2	Very high	81.4	Confident	86 Å²	86	65.2 Å²	65.2	52%	0.521	34%	0.342	S	S	.	.	H	α-helix	trans	-65.7	-43.1	176.7	170.3	0	0	0	0	111.3	E161 H162 I163 R168 T169	E161-V165 VanDerWaalsContact O-CG2 3.27Å; E161-V165 WeakPolarHBondContact O-CG2 3.31Å; E161-V165 PolarHBondContact O-N 2.83Å; H162-V165 PolarHBondContact O-N 2.88Å; I163-V165 VanDerWaalsContact C-N 3.32Å; I163-V165 PolarHBondContact O-N 3.26Å; V165-R168 PolarHBondContact O-N 3.32Å; V165-T169 WeakPolarHBondContact O-CB 3.04Å; V165-T169 PolarHBondContact O-N 3.17Å; V165-T169 PolarHBondContact O-OG1 3.45Å
166	E	91.1	Very high	82.3	Confident	44 Å²	44	63.7 Å²	63.7	21%	0.206	34%	0.336	C	S	.	.	H	α-helix	trans	-61.9	-46.4	175.4	-73.3	-174	147.8	0	0	111.5	H162 I163 R168 T169 F170 I212	H162-E166 IonicContact CE1-OE1 3.52Å; H162-E166 PolarHBondContact CE1-OE1 3.09Å; H162-E166 IonicContact CE1-OE2 2.95Å; H162-E166 IonicContact ND1-OE1 2.63Å; H162-E166 IonicContact ND1-OE2 3.21Å; H162-E166 IonicContact NE2-OE1 3.74Å; H162-E166 WeakPolarHBondContact O-CG 3.42Å; H162-E166 PolarHBondContact O-N 3.26Å; I163-E166 PolarHBondContact O-N 2.84Å; E166-R168 VanDerWaalsContact C-N 3.34Å; E166-R168 PolarHBondContact O-N 3.18Å; E166-T169 PolarHBondContact O-N 3.26Å; E166-F170 WeakPolarHBondContact O-CB 3.48Å; E166-F170 PolarHBondContact O-N 3.03Å; E166-I212 HydrophobicContact CB-CD1 3.95Å
167	C	92.8	Very high	83.7	Confident	0 Å²	0	61.7 Å²	61.7	0%	0	32%	0.321	C	S	.	.	H	α-helix	trans	-59.6	-45	176.4	-69.6	0	0	0	0	111.4	I163 F170 L171 L187 M190 L194	I163-C167 WeakPolarHBondContact O-CB 3.42Å; I163-C167 PolarHBondContact O-N 3.39Å; I163-C167 PolarHBondContact O-SG 3.49Å; C167-F170 PolarHBondContact O-N 3.09Å; C167-L171 WeakPolarHBondContact O-CB 3.48Å; C167-L171 VanDerWaalsContact O-CG 3.3Å; C167-L171 WeakPolarHBondContact O-CG 3.39Å; C167-L171 PolarHBondContact O-N 3.43Å; C167-L187 HydrophobicContact CB-CD1 3.68Å; C167-M190 HydrophobicContact CB-CE 4.26Å; C167-L194 WeakPolarHBondContact SG-CD1 3.39Å
168	R	92.5	Very high	85.1	Confident	133 Å²	133	62.5 Å²	62.5	50%	0.502	33%	0.328	S	S	.	.	H	α-helix	trans	-63.9	-42.1	177.7	-176.7	175.1	-65.8	-144.2	-0.6	111.7	L164 V165 E166 L171 N172 L187	L164-R168 WeakPolarHBondContact O-CB 3.41Å; L164-R168 PolarHBondContact O-N 3.01Å; V165-R168 PolarHBondContact O-N 3.32Å; E166-R168 VanDerWaalsContact C-N 3.34Å; E166-R168 PolarHBondContact O-N 3.18Å; R168-L171 PolarHBondContact O-N 3.32Å; R168-N172 VanDerWaalsContact O-CB 3.32Å; R168-N172 WeakPolarHBondContact O-CB 3.11Å; R168-N172 PolarHBondContact O-N 3.38Å; R168-N172 PolarHBondContact O-ND2 2.92Å; R168-L187 HydrophobicContact CB-CD1 4.16Å
169	T	92.6	Very high	86.6	Confident	85 Å²	85	59 Å²	59	52%	0.521	31%	0.314	S	S	.	.	H	α-helix	trans	-60.8	-47.7	177.6	-58.2	0	0	0	0	110.2	V165 E166 N172 S173	V165-T169 WeakPolarHBondContact O-CB 3.04Å; V165-T169 PolarHBondContact O-N 3.17Å; V165-T169 PolarHBondContact O-OG1 3.45Å; E166-T169 PolarHBondContact O-N 3.26Å; T169-N172 PolarHBondContact O-N 3.34Å; T169-S173 PolarHBondContact O-N 3Å; T169-S173 VanDerWaalsContact O-N 3.14Å; T169-S173 PolarHBondContact O-OG 3.35Å
170	F	92.7	Very high	88.2	Confident	10 Å²	10	53.3 Å²	53.3	4%	0.044	29%	0.287	C	S	.	.	H	α-helix	trans	-60.6	-49.4	176.3	170.6	-101.5	0	0	0	112.8	E166 C167 N172 S173 C174 M177 M190 L209 I212 K213 S216 I352	E166-F170 WeakPolarHBondContact O-CB 3.48Å; E166-F170 PolarHBondContact O-N 3.03Å; C167-F170 PolarHBondContact O-N 3.09Å; F170-N172 PolarHBondContact O-N 2.94Å; F170-S173 PolarHBondContact O-N 3.31Å; F170-S173 VanDerWaalsContact O-N 3.15Å; F170-S173 PolarHBondContact O-OG 2.9Å; F170-S173 VanDerWaalsContact O-OG 3.09Å; F170-C174 HydrophobicContact CD2-CB 4.29Å; F170-C174 HydrophobicContact CE1-CB 4.26Å; F170-C174 HydrophobicContact CE2-CB 3.81Å; F170-C174 HydrophobicContact CZ-CB 3.8Å; F170-C174 VanDerWaalsContact O-CB 3.22Å; F170-C174 WeakPolarHBondContact O-CB 3.29Å; F170-C174 PolarHBondContact O-N 2.93Å; F170-M177 HydrophobicContact CE1-CG 3.97Å; F170-M177 HydrophobicContact CZ-CG 4.22Å; F170-M190 HydrophobicContact CD1-CE 4.19Å; F170-L209 HydrophobicContact CD2-CD1 3.99Å; F170-I212 HydrophobicContact CB-CG2 3.98Å; F170-I212 HydrophobicContact CD1-CG2 3.63Å; F170-I212 HydrophobicContact CE1-CG2 4.31Å; F170-I212 HydrophobicContact CG-CG2 3.77Å; F170-K213 HydrophobicContact CE2-CG 3.79Å; F170-K213 HydrophobicContact CZ-CG 3.93Å; F170-S216 WeakPolarHBondContact CE1-OG 3.38Å; F170-I352 HydrophobicContact CE2-CG2 4.33Å; F170-I352 HydrophobicContact CZ-CG2 3.75Å
171	L	93	Very high	89.4	Confident	2 Å²	2	53.7 Å²	53.7	1%	0.01	29%	0.286	C	S	.	.	H	α-helix	trans	-61.2	-31.6	178.3	-72.9	-178.7	0	0	0	112.4	C167 R168 M177 I180 L187 M190	C167-L171 WeakPolarHBondContact O-CB 3.48Å; C167-L171 VanDerWaalsContact O-CG 3.3Å; C167-L171 WeakPolarHBondContact O-CG 3.39Å; C167-L171 PolarHBondContact O-N 3.43Å; R168-L171 PolarHBondContact O-N 3.32Å; L171-M177 HydrophobicContact CD2-CB 3.79Å; L171-M177 HydrophobicContact CD2-CG 4.25Å; L171-I180 HydrophobicContact CD2-CD1 3.8Å; L171-I180 HydrophobicContact CD2-CG1 3.93Å; L171-L187 HydrophobicContact CD1-CD1 4.16Å; L171-M190 HydrophobicContact CD1-SD 4.02Å; L171-M190 HydrophobicContact CD2-SD 3.9Å; L171-M190 HydrophobicContact CG-SD 4.11Å
172	N	90.2	Very high	90	Very high	80 Å²	80	53.2 Å²	53.2	43%	0.428	29%	0.288	S	S	.	.	H	α-helix	trans	-74.3	-30.3	177.8	-74.4	-23.9	0	0	0	113.3	R168 T169 F170 K181	R168-N172 VanDerWaalsContact O-CB 3.32Å; R168-N172 WeakPolarHBondContact O-CB 3.11Å; R168-N172 PolarHBondContact O-N 3.38Å; R168-N172 PolarHBondContact O-ND2 2.92Å; T169-N172 PolarHBondContact O-N 3.34Å; F170-N172 PolarHBondContact O-N 2.94Å; N172-K181 WeakPolarHBondContact OD1-CE 3.32Å
173	S	89	Confident	90.3	Very high	88 Å²	88	49.4 Å²	49.4	62%	0.615	27%	0.271	S	S	*	.	H	α-helix	trans	-94.3	-26.3	-178.4	61.7	0	0	0	0	114.1	T169 F170 I175	T169-S173 PolarHBondContact O-N 3Å; T169-S173 VanDerWaalsContact O-N 3.14Å; T169-S173 PolarHBondContact O-OG 3.35Å; F170-S173 PolarHBondContact O-N 3.31Å; F170-S173 VanDerWaalsContact O-N 3.15Å; F170-S173 PolarHBondContact O-OG 2.9Å; F170-S173 VanDerWaalsContact O-OG 3.09Å; S173-I175 PolarHBondContact O-N 2.85Å
174	C	90.1	Very high	90.5	Very high	5 Å²	5	51.7 Å²	51.7	3%	0.034	29%	0.285	C	S	.	.			trans	-83	115.7	-173.3	-179	0	0	0	0	112.5	F170 S176 M177 D353	F170-C174 HydrophobicContact CD2-CB 4.29Å; F170-C174 HydrophobicContact CE1-CB 4.26Å; F170-C174 HydrophobicContact CE2-CB 3.81Å; F170-C174 HydrophobicContact CZ-CB 3.8Å; F170-C174 VanDerWaalsContact O-CB 3.22Å; F170-C174 WeakPolarHBondContact O-CB 3.29Å; F170-C174 PolarHBondContact O-N 2.93Å; C174-S176 VanDerWaalsContact C-N 3.33Å; C174-S176 PolarHBondContact O-N 3.48Å; C174-M177 HydrophobicContact CB-CB 4.13Å; C174-M177 HydrophobicContact CB-CG 4.1Å; C174-M177 PolarHBondContact O-N 3.38Å; C174-M177 VanDerWaalsContact SG-CG 3.52Å; C174-D353 WeakPolarHBondContact CB-OD1 3.38Å; C174-D353 PolarHBondContact SG-OD1 2.64Å
175	I	85.6	Confident	90.6	Very high	99 Å²	99	50.2 Å²	50.2	51%	0.508	28%	0.278	S	S	.	.	G	3₁₀ helix	trans	-61.9	-41.2	178	-61.6	170.7	0	0	0	111.2	S173 M177 S178 P440	S173-I175 PolarHBondContact O-N 2.85Å; I175-M177 PolarHBondContact O-N 3.03Å; I175-M177 VanDerWaalsContact O-N 3.13Å; I175-S178 WeakPolarHBondContact O-CB 3.4Å; I175-S178 PolarHBondContact O-N 3.42Å; I175-S178 PolarHBondContact O-OG 2.85Å; I175-S178 VanDerWaalsContact O-OG 3.06Å; I175-P440 HydrophobicContact CD1-CG 4.24Å; I175-P440 HydrophobicContact CG2-CB 4.45Å
176	S	89	Confident	90.7	Very high	0 Å²	0	46.1 Å²	46.1	0%	0	25%	0.253	C	S	.	.	G	3₁₀ helix	trans	-61.7	-22.1	-179	-43.7	0	0	0	0	113.4	C174 D353 L355	C174-S176 VanDerWaalsContact C-N 3.33Å; C174-S176 PolarHBondContact O-N 3.48Å; S176-D353 PolarHBondContact OG-N 2.87Å; S176-L355 WeakPolarHBondContact CB-O 3.34Å; S176-L355 PolarHBondContact OG-O 3.12Å
177	M	91.9	Very high	90.8	Very high	0 Å²	0	44.6 Å²	44.6	0%	0	25%	0.246	C	C	.	.	G	3₁₀ helix	trans	-105.5	10	-175.5	-59.2	-60.9	156.6	0	0	113.5	F170 L171 C174 I175 S179 I180 K181 S216 L220 I352 L360	F170-M177 HydrophobicContact CE1-CG 3.97Å; F170-M177 HydrophobicContact CZ-CG 4.22Å; L171-M177 HydrophobicContact CD2-CB 3.79Å; L171-M177 HydrophobicContact CD2-CG 4.25Å; C174-M177 HydrophobicContact CB-CB 4.13Å; C174-M177 HydrophobicContact CB-CG 4.1Å; C174-M177 PolarHBondContact O-N 3.38Å; C174-M177 VanDerWaalsContact SG-CG 3.52Å; I175-M177 PolarHBondContact O-N 3.03Å; I175-M177 VanDerWaalsContact O-N 3.13Å; M177-S179 PolarHBondContact O-N 3.21Å; M177-I180 HydrophobicContact CB-CD1 4.35Å; M177-I180 HydrophobicContact CB-CG1 4.07Å; M177-I180 VanDerWaalsContact O-CG1 3.26Å; M177-I180 WeakPolarHBondContact O-CG1 3.47Å; M177-I180 PolarHBondContact O-N 3.01Å; M177-I180 HydrophobicContact SD-CD1 3.97Å; M177-I180 HydrophobicContact SD-CG1 4.5Å; M177-K181 PolarHBondContact O-N 2.78Å; M177-S216 VanDerWaalsContact CE-OG 3.29Å; M177-S216 WeakPolarHBondContact CE-OG 3.41Å; M177-L220 HydrophobicContact CE-CD2 3.95Å; M177-L220 HydrophobicContact SD-CB 4.05Å; M177-L220 HydrophobicContact SD-CD1 4.26Å; M177-L220 HydrophobicContact SD-CD2 3.73Å; M177-L220 HydrophobicContact SD-CG 4.23Å; M177-I352 HydrophobicContact CE-CG1 4.33Å; M177-I352 HydrophobicContact CE-CG2 3.86Å; M177-L360 HydrophobicContact CE-CD2 3.97Å
178	S	87.8	Confident	90.8	Very high	75 Å²	75	47.4 Å²	47.4	52%	0.524	26%	0.257	S	S	.	.	T	Hydrogen-bonded Turn	trans	-50.2	-34.6	-177.5	51	0	0	0	0	114.5	I175 I180	I175-S178 WeakPolarHBondContact O-CB 3.4Å; I175-S178 PolarHBondContact O-N 3.42Å; I175-S178 PolarHBondContact O-OG 2.85Å; I175-S178 VanDerWaalsContact O-OG 3.06Å; S178-I180 VanDerWaalsContact C-N 3.34Å; S178-I180 PolarHBondContact O-N 3.35Å
179	S	89.3	Confident	90.8	Very high	55 Å²	55	41 Å²	41	39%	0.385	23%	0.233	S	C	.	.	T	Hydrogen-bonded Turn	trans	-74.4	-16	-179.7	67.6	0	0	0	0	115.8	M177 Q357	M177-S179 PolarHBondContact O-N 3.21Å; S179-Q357 PolarHBondContact OG-NE2 3.48Å; S179-Q357 PolarHBondContact OG-OE1 2.8Å
180	I	91.7	Very high	90.8	Very high	1 Å²	1	37 Å²	37	1%	0.005	21%	0.208	C	C	.	.	T	Hydrogen-bonded Turn	trans	-112.3	-3	-180	60.4	166.8	0	0	0	113.3	L171 M177 S178 D182 S183 C186 V219 L220 K223	L171-I180 HydrophobicContact CD2-CD1 3.8Å; L171-I180 HydrophobicContact CD2-CG1 3.93Å; M177-I180 HydrophobicContact CB-CD1 4.35Å; M177-I180 HydrophobicContact CB-CG1 4.07Å; M177-I180 VanDerWaalsContact O-CG1 3.26Å; M177-I180 WeakPolarHBondContact O-CG1 3.47Å; M177-I180 PolarHBondContact O-N 3.01Å; M177-I180 HydrophobicContact SD-CD1 3.97Å; M177-I180 HydrophobicContact SD-CG1 4.5Å; S178-I180 VanDerWaalsContact C-N 3.34Å; S178-I180 PolarHBondContact O-N 3.35Å; I180-D182 VanDerWaalsContact C-N 3.26Å; I180-D182 PolarHBondContact O-N 3.43Å; I180-S183 WeakPolarHBondContact O-CB 3.37Å; I180-S183 PolarHBondContact O-N 3.15Å; I180-C186 HydrophobicContact CB-CB 3.98Å; I180-C186 HydrophobicContact CD1-CB 4.49Å; I180-C186 HydrophobicContact CG2-CB 4.46Å; I180-V219 HydrophobicContact CD1-CG1 4.3Å; I180-L220 HydrophobicContact CD1-CB 4.32Å; I180-L220 HydrophobicContact CD1-CD1 4.3Å; I180-L220 HydrophobicContact CG1-CD1 4.27Å; I180-L220 HydrophobicContact CG2-CD1 3.91Å; I180-K223 HydrophobicContact CG2-CB 3.42Å; I180-K223 VanDerWaalsContact CG2-CB 3.42Å; I180-K223 HydrophobicContact CG2-CD 4.37Å
181	K	89.8	Confident	90.8	Very high	87 Å²	87	36.6 Å²	36.6	38%	0.378	21%	0.207	S	C	.	.	T	Hydrogen-bonded Turn	trans	-49.9	-42.2	-176.6	177.2	177.5	170.4	169.7	0	114	N172 M177	N172-K181 WeakPolarHBondContact OD1-CE 3.32Å; M177-K181 PolarHBondContact O-N 2.78Å
182	D	88	Confident	90.6	Very high	141 Å²	141	37.9 Å²	37.9	75%	0.754	21%	0.212	S	C	*	.	T	Hydrogen-bonded Turn	trans	-98.8	7	-176.5	-57.8	-43.4	0	0	0	113.5	I180 V184	I180-D182 VanDerWaalsContact C-N 3.26Å; I180-D182 PolarHBondContact O-N 3.43Å; D182-V184 PolarHBondContact O-N 2.87Å
183	S	91.8	Very high	90.6	Very high	11 Å²	11	34.1 Å²	34.1	8%	0.077	19%	0.191	C	C	.	.			trans	-87.7	113.1	-177.7	177.8	0	0	0	0	111.3	I180 G185 C186 L187 S227	I180-S183 WeakPolarHBondContact O-CB 3.37Å; I180-S183 PolarHBondContact O-N 3.15Å; S183-G185 VanDerWaalsContact C-N 3.3Å; S183-G185 PolarHBondContact O-N 2.86Å; S183-C186 PolarHBondContact O-N 2.85Å; S183-C186 PolarHBondContact OG-N 3.4Å; S183-C186 PolarHBondContact OG-SG 2.93Å; S183-L187 PolarHBondContact O-N 3.49Å; S183-S227 PolarHBondContact OG-O 3.47Å
184	V	91.1	Very high	90.7	Very high	52 Å²	52	29.9 Å²	29.9	32%	0.315	16%	0.162	S	C	.	.	H	α-helix	trans	-56.4	-46.8	172.9	176.7	0	0	0	0	110	D182 C186 L187 Y188 K228	D182-V184 PolarHBondContact O-N 2.87Å; V184-C186 VanDerWaalsContact C-N 3.32Å; V184-C186 PolarHBondContact O-N 3.42Å; V184-L187 PolarHBondContact O-N 2.61Å; V184-Y188 HydrophobicContact CG1-CD2 3.62Å; V184-Y188 HydrophobicContact CG1-CE2 3.76Å; V184-Y188 WeakPolarHBondContact O-CD2 3.42Å; V184-Y188 PolarHBondContact O-N 2.99Å; V184-K228 VanDerWaalsContact CB-O 3.31Å; V184-K228 WeakPolarHBondContact CB-O 3.3Å; V184-K228 WeakPolarHBondContact CG2-O 3.42Å; V184-K228 PolarHBondContact N-O 3.24Å
185	G	91.6	Very high	90.4	Very high	0 Å²	0	29.9 Å²	29.9	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-61.5	-38.9	-179.6	0	0	0	0	0	113	S183 A189 S227 Q230	S183-G185 VanDerWaalsContact C-N 3.3Å; S183-G185 PolarHBondContact O-N 2.86Å; G185-A189 VanDerWaalsContact O-CB 3.22Å; G185-A189 WeakPolarHBondContact O-CB 3.33Å; G185-A189 PolarHBondContact O-N 3.09Å; G185-S227 WeakPolarHBondContact CA-O 3.22Å; G185-S227 PolarHBondContact N-O 3.18Å; G185-Q230 WeakPolarHBondContact CA-O 3.47Å; G185-Q230 PolarHBondContact N-O 3.18Å
186	C	93.4	Very high	90.2	Very high	0 Å²	0	25.3 Å²	25.3	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-68	-45.6	176.2	-66	0	0	0	0	112	I180 S183 V184 Y188 A189 M190 V219	I180-C186 HydrophobicContact CB-CB 3.98Å; I180-C186 HydrophobicContact CD1-CB 4.49Å; I180-C186 HydrophobicContact CG2-CB 4.46Å; S183-C186 PolarHBondContact O-N 2.85Å; S183-C186 PolarHBondContact OG-N 3.4Å; S183-C186 PolarHBondContact OG-SG 2.93Å; V184-C186 VanDerWaalsContact C-N 3.32Å; V184-C186 PolarHBondContact O-N 3.42Å; C186-Y188 PolarHBondContact O-N 3.4Å; C186-A189 PolarHBondContact O-N 3.21Å; C186-M190 WeakPolarHBondContact O-CG 3.49Å; C186-M190 PolarHBondContact O-N 2.87Å; C186-V219 HydrophobicContact CB-CG1 3.48Å; C186-V219 VanDerWaalsContact CB-CG1 3.48Å
187	L	93.4	Very high	89.9	Confident	12 Å²	12	25.8 Å²	25.8	6%	0.063	14%	0.139	C	C	.	.	H	α-helix	trans	-59.9	-46.8	178.5	179	65.2	0	0	0	111.6	L164 C167 R168 L171 S183 V184 M190 N191	L164-L187 HydrophobicContact CD1-CD1 4.47Å; L164-L187 HydrophobicContact CD1-CD2 4.16Å; L164-L187 HydrophobicContact CD1-CG 3.96Å; L164-L187 HydrophobicContact CG-CD2 4.27Å; L164-L187 HydrophobicContact CG-CG 4.41Å; C167-L187 HydrophobicContact CB-CD1 3.68Å; R168-L187 HydrophobicContact CB-CD1 4.16Å; L171-L187 HydrophobicContact CD1-CD1 4.16Å; S183-L187 PolarHBondContact O-N 3.49Å; V184-L187 PolarHBondContact O-N 2.61Å; L187-M190 PolarHBondContact O-N 3.15Å; L187-N191 PolarHBondContact O-N 3.26Å
188	Y	91.5	Very high	89.4	Confident	59 Å²	59	27.4 Å²	27.4	23%	0.231	15%	0.147	C	C	.	.	H	α-helix	trans	-68.7	-36.5	177.8	-84.5	-88.3	0	0	0	112.1	P157 L164 V184 C186 M190 N191 Y192 P231	P157-Y188 HydrophobicContact CB-CE1 4.35Å; L164-Y188 HydrophobicContact CD1-CE1 4.49Å; V184-Y188 HydrophobicContact CG1-CD2 3.62Å; V184-Y188 HydrophobicContact CG1-CE2 3.76Å; V184-Y188 WeakPolarHBondContact O-CD2 3.42Å; V184-Y188 PolarHBondContact O-N 2.99Å; C186-Y188 PolarHBondContact O-N 3.4Å; Y188-M190 PolarHBondContact O-N 3.46Å; Y188-N191 WeakPolarHBondContact O-CB 3.49Å; Y188-N191 PolarHBondContact O-N 3.14Å; Y188-Y192 HydrophobicContact CD1-CE2 4.23Å; Y188-Y192 WeakPolarHBondContact O-CD2 3.42Å; Y188-Y192 PolarHBondContact O-N 3.03Å; Y188-P231 HydrophobicContact CD1-CB 4.3Å; Y188-P231 HydrophobicContact CD2-CB 4.38Å; Y188-P231 HydrophobicContact CG-CB 3.99Å
189	A	92.7	Very high	88.9	Confident	0 Å²	0	27.9 Å²	27.9	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-58	-48.5	173	0	0	0	0	0	111.8	G185 C186 N191 Y192 L193 V219 L226 P232 I237 L240	G185-A189 VanDerWaalsContact O-CB 3.22Å; G185-A189 WeakPolarHBondContact O-CB 3.33Å; G185-A189 PolarHBondContact O-N 3.09Å; C186-A189 PolarHBondContact O-N 3.21Å; A189-N191 VanDerWaalsContact C-N 3.34Å; A189-N191 PolarHBondContact O-N 3.27Å; A189-Y192 PolarHBondContact O-N 3.29Å; A189-L193 VanDerWaalsContact O-CG 3.27Å; A189-L193 WeakPolarHBondContact O-CG 3.29Å; A189-L193 PolarHBondContact O-N 3.43Å; A189-L193 VanDerWaalsContact O-N 3.13Å; A189-V219 HydrophobicContact CB-CG1 4.39Å; A189-V219 HydrophobicContact CB-CG2 3.82Å; A189-L226 HydrophobicContact CB-CD1 4Å; A189-P232 HydrophobicContact CB-CG 4.19Å; A189-I237 HydrophobicContact CB-CD1 4.13Å; A189-L240 HydrophobicContact CB-CD1 4.08Å
190	M	93.6	Very high	88.1	Confident	0 Å²	0	25.9 Å²	25.9	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-58.5	-46.3	175.1	-68.9	178.3	60.8	0	0	111.6	C167 F170 L171 C186 L187 Y188 Y192 L193 L194 I212 V219	C167-M190 HydrophobicContact CB-CE 4.26Å; F170-M190 HydrophobicContact CD1-CE 4.19Å; L171-M190 HydrophobicContact CD1-SD 4.02Å; L171-M190 HydrophobicContact CD2-SD 3.9Å; L171-M190 HydrophobicContact CG-SD 4.11Å; C186-M190 WeakPolarHBondContact O-CG 3.49Å; C186-M190 PolarHBondContact O-N 2.87Å; L187-M190 PolarHBondContact O-N 3.15Å; Y188-M190 PolarHBondContact O-N 3.46Å; M190-Y192 PolarHBondContact O-N 3.26Å; M190-L193 PolarHBondContact O-N 3.45Å; M190-L194 WeakPolarHBondContact O-CB 3.22Å; M190-L194 VanDerWaalsContact O-CG 3.27Å; M190-L194 WeakPolarHBondContact O-CG 3.47Å; M190-L194 PolarHBondContact O-N 3.3Å; M190-I212 HydrophobicContact CE-CG2 3.66Å; M190-V219 HydrophobicContact CG-CB 4.11Å; M190-V219 HydrophobicContact CG-CG1 4.25Å; M190-V219 HydrophobicContact CG-CG2 3.77Å
191	N	91.5	Very high	87.2	Confident	2 Å²	2	26.7 Å²	26.7	1%	0.011	13%	0.131	C	C	.	.	H	α-helix	trans	-57.6	-48.4	179.2	-171.1	38.2	0	0	0	112.2	I163 L164 L187 Y188 A189 L193 L194 K195	I163-N191 WeakPolarHBondContact CG2-OD1 3.5Å; L164-N191 HydrophobicContact CD1-CB 3.93Å; L187-N191 PolarHBondContact O-N 3.26Å; Y188-N191 WeakPolarHBondContact O-CB 3.49Å; Y188-N191 PolarHBondContact O-N 3.14Å; A189-N191 VanDerWaalsContact C-N 3.34Å; A189-N191 PolarHBondContact O-N 3.27Å; N191-L193 PolarHBondContact O-N 2.98Å; N191-L194 PolarHBondContact O-N 3.45Å; N191-K195 PolarHBondContact ND2-NZ 3.32Å; N191-K195 WeakPolarHBondContact O-CB 3.5Å; N191-K195 VanDerWaalsContact O-CG 3.3Å; N191-K195 WeakPolarHBondContact O-CG 3.36Å; N191-K195 PolarHBondContact O-N 3.28Å
192	Y	89.1	Confident	86.1	Confident	29 Å²	29	26.3 Å²	26.3	11%	0.114	13%	0.133	C	C	.	.	H	α-helix	trans	-63	-41.8	179.5	-77	-64.7	0	0	0	112.8	F155 Y188 A189 M190 L194 F196 I237	F155-Y192 HydrophobicContact CB-CD1 4.37Å; F155-Y192 HydrophobicContact CB-CE1 4.19Å; F155-Y192 HydrophobicContact CD2-CD1 4.29Å; Y188-Y192 HydrophobicContact CD1-CE2 4.23Å; Y188-Y192 WeakPolarHBondContact O-CD2 3.42Å; Y188-Y192 PolarHBondContact O-N 3.03Å; A189-Y192 PolarHBondContact O-N 3.29Å; M190-Y192 PolarHBondContact O-N 3.26Å; Y192-L194 VanDerWaalsContact C-N 3.34Å; Y192-L194 PolarHBondContact O-N 3Å; Y192-F196 VanDerWaalsContact O-CB 3.29Å; Y192-F196 WeakPolarHBondContact O-CB 3.4Å; Y192-F196 PolarHBondContact O-N 3Å; Y192-I237 HydrophobicContact CD2-CD1 3.91Å; Y192-I237 HydrophobicContact CD2-CG1 3.92Å; Y192-I237 HydrophobicContact CG-CD1 4.33Å; Y192-I237 HydrophobicContact CG-CG1 4.26Å; Y192-I237 HydrophobicContact CG-CG2 4.1Å
193	L	90.5	Very high	85.1	Confident	0 Å²	0	21.6 Å²	21.6	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-62.5	-43.3	178.5	-66	173.5	0	0	0	112.1	A189 M190 N191 F196 Y197 L218 V219 L240 S241 F244	A189-L193 VanDerWaalsContact O-CG 3.27Å; A189-L193 WeakPolarHBondContact O-CG 3.29Å; A189-L193 PolarHBondContact O-N 3.43Å; A189-L193 VanDerWaalsContact O-N 3.13Å; M190-L193 PolarHBondContact O-N 3.45Å; N191-L193 PolarHBondContact O-N 2.98Å; L193-F196 PolarHBondContact O-N 3.34Å; L193-Y197 WeakPolarHBondContact O-CB 3.45Å; L193-Y197 PolarHBondContact O-N 3.4Å; L193-L218 HydrophobicContact CD1-CD2 4.33Å; L193-V219 HydrophobicContact CD1-CG2 4.13Å; L193-L240 HydrophobicContact CD1-CB 4.38Å; L193-L240 HydrophobicContact CD2-CB 3.81Å; L193-L240 WeakPolarHBondContact CD2-O 3.29Å; L193-S241 VanDerWaalsContact CD2-CA 3.41Å; L193-S241 VanDerWaalsContact CD2-N 3.34Å; L193-F244 HydrophobicContact CB-CD1 4.4Å; L193-F244 HydrophobicContact CB-CG 4.5Å; L193-F244 HydrophobicContact CD2-CB 4.03Å; L193-F244 HydrophobicContact CD2-CG 4.5Å
194	L	90.4	Very high	83.8	Confident	0 Å²	0	28.8 Å²	28.8	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-73.4	-37.4	-178.8	-69.8	-179.9	0	0	0	112.6	I163 C167 M190 N191 Y192 Y197 Q198 I207 I212 A215 F244	I163-L194 HydrophobicContact CG2-CB 3.83Å; I163-L194 HydrophobicContact CG2-CD1 4.03Å; C167-L194 WeakPolarHBondContact SG-CD1 3.39Å; M190-L194 WeakPolarHBondContact O-CB 3.22Å; M190-L194 VanDerWaalsContact O-CG 3.27Å; M190-L194 WeakPolarHBondContact O-CG 3.47Å; M190-L194 PolarHBondContact O-N 3.3Å; N191-L194 PolarHBondContact O-N 3.45Å; Y192-L194 VanDerWaalsContact C-N 3.34Å; Y192-L194 PolarHBondContact O-N 3Å; L194-Y197 WeakPolarHBondContact O-CB 3.21Å; L194-Y197 PolarHBondContact O-N 3.3Å; L194-Q198 WeakPolarHBondContact O-CB 3.11Å; L194-Q198 PolarHBondContact O-N 3.11Å; L194-I207 HydrophobicContact CB-CD1 3.65Å; L194-I207 HydrophobicContact CD1-CG2 4.46Å; L194-I207 HydrophobicContact CD2-CG2 3.98Å; L194-I212 HydrophobicContact CD1-CB 4.39Å; L194-I212 HydrophobicContact CD1-CG1 3.76Å; L194-A215 HydrophobicContact CD2-CB 4.02Å; L194-A215 HydrophobicContact CG-CB 4.19Å; L194-F244 HydrophobicContact CD2-CZ 4.37Å
195	K	85.7	Confident	82.6	Confident	5 Å²	5	32.4 Å²	32.4	2%	0.022	16%	0.161	C	C	.	.	H	α-helix	trans	-58.9	-48.4	169.2	-80	178	169	-179.5	0	111.6	S156 P157 Q159 D160 I163 N191 Y197 Q198 M199	S156-K195 PolarHBondContact O-NZ 2.81Å; P157-K195 PolarHBondContact O-NZ 3.14Å; Q159-K195 WeakPolarHBondContact O-CE 3.39Å; Q159-K195 PolarHBondContact O-NZ 3.16Å; D160-K195 WeakPolarHBondContact OD2-CE 3.45Å; I163-K195 HydrophobicContact CD1-CG 3.64Å; N191-K195 PolarHBondContact ND2-NZ 3.32Å; N191-K195 WeakPolarHBondContact O-CB 3.5Å; N191-K195 VanDerWaalsContact O-CG 3.3Å; N191-K195 WeakPolarHBondContact O-CG 3.36Å; N191-K195 PolarHBondContact O-N 3.28Å; K195-Y197 VanDerWaalsContact C-N 3.28Å; K195-Y197 PolarHBondContact O-N 3.31Å; K195-Q198 PolarHBondContact O-N 2.85Å; K195-M199 WeakPolarHBondContact O-CB 3.4Å; K195-M199 PolarHBondContact O-N 2.96Å
196	F	81.4	Confident	81.8	Confident	2 Å²	2	37.6 Å²	37.6	1%	0.009	19%	0.188	C	C	.	.	H	α-helix	trans	-62.9	-38	179.3	-173.3	-89	0	0	0	111.4	F148 I151 I152 F155 Y192 L193 M199 I200 F245	F148-F196 AromaticContact CD1-CE1 3.65Å; F148-F196 HydrophobicContact CD1-CE1 3.65Å; F148-F196 AromaticContact CD1-CE2 3.75Å; F148-F196 HydrophobicContact CD1-CE2 3.75Å; F148-F196 AromaticContact CD1-CZ 3.15Å; F148-F196 HydrophobicContact CD1-CZ 3.15Å; F148-F196 HydrophobicContact CE1-CD1 4.49Å; F148-F196 AromaticContact CE1-CE1 3.36Å; F148-F196 HydrophobicContact CE1-CE1 3.36Å; F148-F196 HydrophobicContact CE1-CE2 4.25Å; F148-F196 AromaticContact CE1-CZ 3.22Å; F148-F196 HydrophobicContact CE1-CZ 3.22Å; F148-F196 HydrophobicContact CG-CZ 4.3Å; F148-F196 HydrophobicContact CZ-CZ 4.39Å; I151-F196 HydrophobicContact CB-CE2 3.97Å; I151-F196 HydrophobicContact CD1-CE2 4.01Å; I151-F196 HydrophobicContact CD1-CZ 4.44Å; I151-F196 HydrophobicContact CG2-CD2 3.77Å; I151-F196 HydrophobicContact CG2-CE2 3.57Å; I152-F196 HydrophobicContact CG1-CD2 4.49Å; F155-F196 HydrophobicContact CE2-CB 3.8Å; F155-F196 AromaticContact CE2-CD2 3.72Å; F155-F196 HydrophobicContact CE2-CD2 3.72Å; F155-F196 HydrophobicContact CE2-CG 4.23Å; F155-F196 HydrophobicContact CZ-CB 4.01Å; F155-F196 AromaticContact CZ-CD2 3.86Å; F155-F196 HydrophobicContact CZ-CD2 3.86Å; F155-F196 HydrophobicContact CZ-CG 4.36Å; Y192-F196 VanDerWaalsContact O-CB 3.29Å; Y192-F196 WeakPolarHBondContact O-CB 3.4Å; Y192-F196 PolarHBondContact O-N 3Å; L193-F196 PolarHBondContact O-N 3.34Å; F196-M199 HydrophobicContact CD2-CE 4.26Å; F196-M199 HydrophobicContact CE2-CE 4.25Å; F196-I200 HydrophobicContact CD1-CD1 3.73Å; F196-I200 HydrophobicContact CE1-CD1 3.11Å; F196-I200 HydrophobicContact CE1-CG1 4.34Å; F196-I200 HydrophobicContact CE2-CD1 4.39Å; F196-I200 HydrophobicContact CZ-CD1 3.49Å; F196-I200 VanDerWaalsContact CZ-CD1 3.49Å; F196-I200 PolarHBondContact O-N 3.34Å; F196-F245 HydrophobicContact CD1-CD2 4.15Å; F196-F245 HydrophobicContact CD1-CE1 4.45Å; F196-F245 AromaticContact CD1-CE2 3.24Å; F196-F245 HydrophobicContact CD1-CE2 3.24Å; F196-F245 AromaticContact CD1-CZ 3.41Å; F196-F245 HydrophobicContact CD1-CZ 3.41Å; F196-F245 VanDerWaalsContact CD1-CZ 3.41Å; F196-F245 HydrophobicContact CE1-CD2 4.09Å; F196-F245 HydrophobicContact CE1-CE1 4.14Å; F196-F245 AromaticContact CE1-CE2 3.49Å; F196-F245 HydrophobicContact CE1-CE2 3.49Å; F196-F245 VanDerWaalsContact CE1-CE2 3.49Å; F196-F245 AromaticContact CE1-CZ 3.49Å; F196-F245 HydrophobicContact CE1-CZ 3.49Å; F196-F245 VanDerWaalsContact CE1-CZ 3.49Å
197	Y	82.5	Confident	81.3	Confident	10 Å²	10	38.1 Å²	38.1	4%	0.039	19%	0.191	C	C	.	.	H	α-helix	trans	-60.7	-50.7	170.3	175.2	-100	0	0	0	113.3	L193 L194 K195 M199 I200 M201 Y211 F244 L248 L258 W262	L193-Y197 WeakPolarHBondContact O-CB 3.45Å; L193-Y197 PolarHBondContact O-N 3.4Å; L194-Y197 WeakPolarHBondContact O-CB 3.21Å; L194-Y197 PolarHBondContact O-N 3.3Å; K195-Y197 VanDerWaalsContact C-N 3.28Å; K195-Y197 PolarHBondContact O-N 3.31Å; Y197-M199 VanDerWaalsContact C-N 3.3Å; Y197-M199 PolarHBondContact O-N 3.45Å; Y197-I200 PolarHBondContact O-N 2.99Å; Y197-M201 HydrophobicContact CD1-CG 4.4Å; Y197-M201 HydrophobicContact CD2-CG 4.08Å; Y197-M201 HydrophobicContact CE1-CG 3.9Å; Y197-M201 HydrophobicContact CE2-CG 3.53Å; Y197-M201 HydrophobicContact CE2-SD 4.11Å; Y197-M201 HydrophobicContact CG-CG 4.47Å; Y197-M201 VanDerWaalsContact CZ-CG 3.42Å; Y197-M201 WeakPolarHBondContact O-CG 3.28Å; Y197-M201 PolarHBondContact O-N 2.93Å; Y197-Y211 HydrophobicContact CE1-CD1 4.38Å; Y197-Y211 AromaticContact CE1-CD2 3.72Å; Y197-Y211 HydrophobicContact CE1-CD2 3.72Å; Y197-Y211 HydrophobicContact CE1-CE1 4.46Å; Y197-Y211 AromaticContact CE1-CE2 3.79Å; Y197-Y211 HydrophobicContact CE1-CE2 3.79Å; Y197-Y211 HydrophobicContact CE1-CG 4.04Å; Y197-Y211 HydrophobicContact CE2-CD1 4.43Å; Y197-Y211 HydrophobicContact CE2-CE1 4.21Å; Y197-Y211 AromaticContact CZ-CE1 3.81Å; Y197-Y211 AromaticContact CZ-CE2 3.69Å; Y197-Y211 AromaticContact CZ-CZ 3.61Å; Y197-Y211 WeakPolarHBondContact OH-CE2 3.3Å; Y197-Y211 PolarHBondContact OH-OH 3.06Å; Y197-Y211 VanDerWaalsContact OH-OH 3.1Å; Y197-F244 HydrophobicContact CD2-CE1 4.36Å; Y197-F244 HydrophobicContact CG-CE1 4.39Å; Y197-L248 HydrophobicContact CD2-CD1 3.84Å; Y197-L248 HydrophobicContact CE2-CD1 3.98Å; Y197-L258 HydrophobicContact CE2-CD2 3.93Å; Y197-L258 WeakPolarHBondContact OH-CD2 3.35Å; Y197-W262 HydrophobicContact CD2-CH2 4.32Å; Y197-W262 HydrophobicContact CE2-CH2 4.23Å
198	Q	81.1	Confident	80.8	Confident	35 Å²	35	42 Å²	42	16%	0.164	20%	0.204	C	C	.	.	H	α-helix	trans	-61	-41.1	-179.2	-171.7	175.5	-3.1	0	0	111.9	I163 L194 K195 I200 M201 N202 T203 I207	I163-Q198 VanDerWaalsContact CD1-OE1 3.26Å; L194-Q198 WeakPolarHBondContact O-CB 3.11Å; L194-Q198 PolarHBondContact O-N 3.11Å; K195-Q198 PolarHBondContact O-N 2.85Å; Q198-I200 VanDerWaalsContact C-N 3.35Å; Q198-I200 PolarHBondContact O-N 3.48Å; Q198-M201 PolarHBondContact O-N 2.64Å; Q198-N202 PolarHBondContact O-N 3.49Å; Q198-T203 WeakPolarHBondContact CG-O 3.46Å; Q198-T203 PolarHBondContact NE2-O 3.38Å; Q198-T203 PolarHBondContact O-N 2.87Å; Q198-I207 HydrophobicContact CB-CD1 4.34Å
199	M	77.7	Confident	80.6	Confident	84 Å²	84	43.7 Å²	43.7	41%	0.414	22%	0.217	S	C	.	.	H	α-helix	trans	-58.9	-45.9	175.9	-170.7	-164.4	69.3	0	0	111.4	I151 F155 K195 F196 Y197 N202	I151-M199 HydrophobicContact CD1-CE 4.45Å; I151-M199 HydrophobicContact CG2-CE 3.33Å; I151-M199 HydrophobicContact CG2-SD 3.74Å; F155-M199 HydrophobicContact CE1-CB 4.39Å; F155-M199 HydrophobicContact CE1-CG 4.46Å; F155-M199 HydrophobicContact CE1-SD 3.65Å; F155-M199 HydrophobicContact CZ-CB 4.41Å; F155-M199 HydrophobicContact CZ-CE 4.25Å; F155-M199 HydrophobicContact CZ-SD 3.73Å; K195-M199 WeakPolarHBondContact O-CB 3.4Å; K195-M199 PolarHBondContact O-N 2.96Å; F196-M199 HydrophobicContact CD2-CE 4.26Å; F196-M199 HydrophobicContact CE2-CE 4.25Å; Y197-M199 VanDerWaalsContact C-N 3.3Å; Y197-M199 PolarHBondContact O-N 3.45Å; M199-N202 PolarHBondContact O-N 3.05Å
200	I	72.7	Confident	80.2	Confident	13 Å²	13	44.5 Å²	44.5	7%	0.067	22%	0.221	C	C	.	.	H	α-helix	trans	-70	-40	-179.7	-76.4	171.4	0	0	0	112.3	F196 Y197 Q198 N202 F245 W262 V271	F196-I200 HydrophobicContact CD1-CD1 3.73Å; F196-I200 HydrophobicContact CE1-CD1 3.11Å; F196-I200 HydrophobicContact CE1-CG1 4.34Å; F196-I200 HydrophobicContact CE2-CD1 4.39Å; F196-I200 HydrophobicContact CZ-CD1 3.49Å; F196-I200 VanDerWaalsContact CZ-CD1 3.49Å; F196-I200 PolarHBondContact O-N 3.34Å; Y197-I200 PolarHBondContact O-N 2.99Å; Q198-I200 VanDerWaalsContact C-N 3.35Å; Q198-I200 PolarHBondContact O-N 3.48Å; I200-N202 PolarHBondContact O-N 3.13Å; I200-F245 HydrophobicContact CB-CE1 4.34Å; I200-F245 HydrophobicContact CB-CZ 4.42Å; I200-F245 HydrophobicContact CD1-CD1 4.4Å; I200-F245 HydrophobicContact CD1-CE1 3.37Å; I200-F245 HydrophobicContact CD1-CE2 4.48Å; I200-F245 HydrophobicContact CD1-CZ 3.42Å; I200-F245 VanDerWaalsContact CD1-CZ 3.42Å; I200-F245 HydrophobicContact CG1-CE1 4.44Å; I200-F245 HydrophobicContact CG1-CZ 4.44Å; I200-F245 HydrophobicContact CG2-CE1 4.14Å; I200-W262 HydrophobicContact CG2-CH2 4.03Å; I200-W262 HydrophobicContact CG2-CZ3 3.97Å; I200-V271 HydrophobicContact CB-CG1 4.22Å; I200-V271 HydrophobicContact CD1-CG1 3.63Å; I200-V271 HydrophobicContact CG1-CG1 3.68Å; I200-V271 HydrophobicContact CG2-CG1 3.54Å; I200-V271 HydrophobicContact CG2-CG2 4.16Å
201	M	71.1	Confident	80	Confident	18 Å²	18	44.8 Å²	44.8	9%	0.089	22%	0.222	C	C	.	.	H	α-helix	trans	-71.5	-15.2	177.5	-68.5	-60.7	-69.9	0	0	112.5	Y197 Q198 T203 L258 W262	Y197-M201 HydrophobicContact CD1-CG 4.4Å; Y197-M201 HydrophobicContact CD2-CG 4.08Å; Y197-M201 HydrophobicContact CE1-CG 3.9Å; Y197-M201 HydrophobicContact CE2-CG 3.53Å; Y197-M201 HydrophobicContact CE2-SD 4.11Å; Y197-M201 HydrophobicContact CG-CG 4.47Å; Y197-M201 VanDerWaalsContact CZ-CG 3.42Å; Y197-M201 WeakPolarHBondContact O-CG 3.28Å; Y197-M201 PolarHBondContact O-N 2.93Å; Q198-M201 PolarHBondContact O-N 2.64Å; M201-T203 HydrophobicContact CB-CG2 3.97Å; M201-T203 PolarHBondContact O-N 3.38Å; M201-L258 HydrophobicContact CE-CD2 4.12Å; M201-L258 HydrophobicContact SD-CD2 4.24Å; M201-W262 HydrophobicContact CG-CZ3 4.43Å; M201-W262 HydrophobicContact SD-CE3 3.92Å; M201-W262 HydrophobicContact SD-CH2 4.16Å; M201-W262 HydrophobicContact SD-CZ3 3.35Å; M201-W262 WeakPolarHBondContact SD-CZ3 3.1Å
202	N	67.7	Low	80	Confident	79 Å²	79	45 Å²	45	42%	0.422	22%	0.223	S	C	.	.	T	Hydrogen-bonded Turn	trans	51.6	40.1	-175.3	-174.9	76.8	0	0	0	111.2	Q198 M199 I200 R278	Q198-N202 PolarHBondContact O-N 3.49Å; M199-N202 PolarHBondContact O-N 3.05Å; I200-N202 PolarHBondContact O-N 3.13Å; N202-R278 HydrophobicContact CB-CG 4.22Å
203	T	66.6	Low	80.1	Confident	43 Å²	43	44.5 Å²	44.5	26%	0.264	22%	0.221	S	C	.	.			trans	-105.6	123.5	179.2	51.6	0	0	0	0	109.7	Q198 M201 E205	Q198-T203 WeakPolarHBondContact CG-O 3.46Å; Q198-T203 PolarHBondContact NE2-O 3.38Å; Q198-T203 PolarHBondContact O-N 2.87Å; M201-T203 HydrophobicContact CB-CG2 3.97Å; M201-T203 PolarHBondContact O-N 3.38Å; T203-E205 PolarHBondContact O-N 3.17Å
204	N	64.2	Low	80.2	Confident	161 Å²	161	44.5 Å²	44.5	86%	0.861	22%	0.222	S	C	*	.			trans	-82.9	4.7	165.7	-67.5	-5.4	0	0	0	111.7
205	E	66.7	Low	80.4	Confident	129 Å²	129	44.5 Å²	44.5	60%	0.603	22%	0.222	S	C	*	.	S	Bend	trans	-74.3	150.1	178	-62.9	-174.6	176.4	0	0	110.8	T203 I207	T203-E205 PolarHBondContact O-N 3.17Å; E205-I207 PolarHBondContact O-N 3.4Å
206	N	75.3	Confident	80.8	Confident	108 Å²	108	44.3 Å²	44.3	58%	0.578	22%	0.221	S	C	*	.	P	Polyproline II helix	trans	-56.3	139.7	172.9	-69	-3.3	0	0	0	110.2	H162 R208	H162-N206 PolarHBondContact CE1-OD1 2.78Å; N206-R208 PolarHBondContact O-N 3.5Å
207	I	81.4	Confident	81.4	Confident	12 Å²	12	44.2 Å²	44.2	6%	0.062	22%	0.22	C	C	.	.	P	Polyproline II helix	trans	-66.9	121.7	-179.1	-61.3	-171.3	0	0	0	108.1	I163 L194 Q198 E205 L209 Y211 I212	I163-I207 HydrophobicContact CB-CD1 4.49Å; I163-I207 HydrophobicContact CD1-CD1 3.72Å; I163-I207 HydrophobicContact CG1-CD1 3.73Å; I163-I207 HydrophobicContact CG1-CG1 4.44Å; I163-I207 HydrophobicContact CG2-CD1 3.98Å; L194-I207 HydrophobicContact CB-CD1 3.65Å; L194-I207 HydrophobicContact CD1-CG2 4.46Å; L194-I207 HydrophobicContact CD2-CG2 3.98Å; Q198-I207 HydrophobicContact CB-CD1 4.34Å; E205-I207 PolarHBondContact O-N 3.4Å; I207-L209 PolarHBondContact O-N 3.06Å; I207-Y211 HydrophobicContact CG2-CD2 4.47Å; I207-I212 HydrophobicContact CG2-CG1 4.11Å
208	R	84	Confident	81.9	Confident	92 Å²	92	43.8 Å²	43.8	35%	0.347	22%	0.219	S	C	.	.	P	Polyproline II helix	trans	-61.9	140.2	179.3	-61.9	-178.3	-179.3	178.9	7.9	110.1	N206 H210 Y211	N206-R208 PolarHBondContact O-N 3.5Å; R208-H210 VanDerWaalsContact CB-CE1 3.41Å; R208-H210 WeakPolarHBondContact CB-CE1 3.4Å; R208-H210 WeakPolarHBondContact CB-ND1 2.95Å; R208-H210 VanDerWaalsContact CD-CE1 3.47Å; R208-H210 WeakPolarHBondContact CD-CE1 3.32Å; R208-H210 PolarHBondContact O-N 3.38Å; R208-H210 VanDerWaalsContact O-N 3.09Å; R208-Y211 HydrophobicContact CB-CD2 3.86Å; R208-Y211 HydrophobicContact CB-CE2 4.02Å; R208-Y211 HydrophobicContact CG-CE2 4.38Å; R208-Y211 PolarHBondContact O-N 2.93Å
209	L	86.3	Confident	82.5	Confident	95 Å²	95	42.1 Å²	42.1	50%	0.497	21%	0.211	S	C	.	.	H	α-helix	trans	-54.3	-34.1	-174.9	-178.1	63.3	0	0	0	113.3	F170 I207 Y211 I212 K213	F170-L209 HydrophobicContact CD2-CD1 3.99Å; I207-L209 PolarHBondContact O-N 3.06Å; L209-Y211 VanDerWaalsContact C-N 3.3Å; L209-Y211 PolarHBondContact O-N 3.41Å; L209-I212 HydrophobicContact CD1-CD1 4.43Å; L209-I212 WeakPolarHBondContact O-CB 3.18Å; L209-I212 PolarHBondContact O-N 3.46Å; L209-K213 WeakPolarHBondContact O-CG 3.44Å; L209-K213 PolarHBondContact O-N 3.43Å
210	H	84.7	Confident	83.3	Confident	18 Å²	18	38.1 Å²	38.1	8%	0.083	19%	0.191	C	C	.	.	H	α-helix	trans	-65.4	-30.1	179.3	66.8	-85.3	0	0	0	113.1	R208 K213 I214 I255 T256	R208-H210 VanDerWaalsContact CB-CE1 3.41Å; R208-H210 WeakPolarHBondContact CB-CE1 3.4Å; R208-H210 WeakPolarHBondContact CB-ND1 2.95Å; R208-H210 VanDerWaalsContact CD-CE1 3.47Å; R208-H210 WeakPolarHBondContact CD-CE1 3.32Å; R208-H210 PolarHBondContact O-N 3.38Å; R208-H210 VanDerWaalsContact O-N 3.09Å; H210-K213 WeakPolarHBondContact O-CB 3.37Å; H210-K213 PolarHBondContact O-N 3.28Å; H210-I214 VanDerWaalsContact O-CG1 3.29Å; H210-I214 WeakPolarHBondContact O-CG1 3.34Å; H210-I214 PolarHBondContact O-N 3.33Å; H210-I255 PolarHBondContact CD2-O 3.13Å; H210-T256 PolarHBondContact NE2-O 3.43Å
211	Y	88.8	Confident	84.1	Confident	6 Å²	6	37.7 Å²	37.7	2%	0.024	19%	0.19	C	C	.	.	H	α-helix	trans	-70.3	-37.6	173.4	-61.2	-58.3	0	0	0	111.8	Y197 I207 R208 L209 K213 I214 A215 L248 T256 L258	Y197-Y211 HydrophobicContact CE1-CD1 4.38Å; Y197-Y211 AromaticContact CE1-CD2 3.72Å; Y197-Y211 HydrophobicContact CE1-CD2 3.72Å; Y197-Y211 HydrophobicContact CE1-CE1 4.46Å; Y197-Y211 AromaticContact CE1-CE2 3.79Å; Y197-Y211 HydrophobicContact CE1-CE2 3.79Å; Y197-Y211 HydrophobicContact CE1-CG 4.04Å; Y197-Y211 HydrophobicContact CE2-CD1 4.43Å; Y197-Y211 HydrophobicContact CE2-CE1 4.21Å; Y197-Y211 AromaticContact CZ-CE1 3.81Å; Y197-Y211 AromaticContact CZ-CE2 3.69Å; Y197-Y211 AromaticContact CZ-CZ 3.61Å; Y197-Y211 WeakPolarHBondContact OH-CE2 3.3Å; Y197-Y211 PolarHBondContact OH-OH 3.06Å; Y197-Y211 VanDerWaalsContact OH-OH 3.1Å; I207-Y211 HydrophobicContact CG2-CD2 4.47Å; R208-Y211 HydrophobicContact CB-CD2 3.86Å; R208-Y211 HydrophobicContact CB-CE2 4.02Å; R208-Y211 HydrophobicContact CG-CE2 4.38Å; R208-Y211 PolarHBondContact O-N 2.93Å; L209-Y211 VanDerWaalsContact C-N 3.3Å; L209-Y211 PolarHBondContact O-N 3.41Å; Y211-K213 VanDerWaalsContact C-N 3.29Å; Y211-K213 PolarHBondContact O-N 3.35Å; Y211-I214 PolarHBondContact O-N 3.39Å; Y211-A215 WeakPolarHBondContact O-CB 3.41Å; Y211-A215 PolarHBondContact O-N 3.31Å; Y211-L248 HydrophobicContact CD1-CD2 4.1Å; Y211-L248 HydrophobicContact CE1-CD2 4.26Å; Y211-T256 VanDerWaalsContact CE1-O 3.26Å; Y211-T256 WeakPolarHBondContact CE1-O 3.41Å; Y211-T256 VanDerWaalsContact CZ-O 3.27Å; Y211-T256 PolarHBondContact OH-O 3.32Å; Y211-L258 HydrophobicContact CE1-CD2 4.18Å; Y211-L258 HydrophobicContact CE1-CG 4.45Å; Y211-L258 WeakPolarHBondContact OH-CD2 3.41Å
212	I	92.2	Very high	84.9	Confident	5 Å²	5	37.2 Å²	37.2	3%	0.026	19%	0.187	C	C	.	.	H	α-helix	trans	-59.5	-44.5	172	-59.8	173.9	0	0	0	109.6	E166 F170 M190 L194 I207 L209 A215 S216	E166-I212 HydrophobicContact CB-CD1 3.95Å; F170-I212 HydrophobicContact CB-CG2 3.98Å; F170-I212 HydrophobicContact CD1-CG2 3.63Å; F170-I212 HydrophobicContact CE1-CG2 4.31Å; F170-I212 HydrophobicContact CG-CG2 3.77Å; M190-I212 HydrophobicContact CE-CG2 3.66Å; L194-I212 HydrophobicContact CD1-CB 4.39Å; L194-I212 HydrophobicContact CD1-CG1 3.76Å; I207-I212 HydrophobicContact CG2-CG1 4.11Å; L209-I212 HydrophobicContact CD1-CD1 4.43Å; L209-I212 WeakPolarHBondContact O-CB 3.18Å; L209-I212 PolarHBondContact O-N 3.46Å; I212-A215 PolarHBondContact O-N 2.88Å; I212-S216 WeakPolarHBondContact O-CB 3.43Å; I212-S216 PolarHBondContact O-N 3.44Å; I212-S216 PolarHBondContact O-OG 2.88Å
213	K	92.4	Very high	85.8	Confident	19 Å²	19	36.3 Å²	36.3	8%	0.083	18%	0.18	C	C	.	.	H	α-helix	trans	-59.7	-50.9	175.8	-69	-178.3	175.4	-159.7	0	111.5	F170 L209 H210 Y211 A215 S216 I217 S349 I352 D353	F170-K213 HydrophobicContact CE2-CG 3.79Å; F170-K213 HydrophobicContact CZ-CG 3.93Å; L209-K213 WeakPolarHBondContact O-CG 3.44Å; L209-K213 PolarHBondContact O-N 3.43Å; H210-K213 WeakPolarHBondContact O-CB 3.37Å; H210-K213 PolarHBondContact O-N 3.28Å; Y211-K213 VanDerWaalsContact C-N 3.29Å; Y211-K213 PolarHBondContact O-N 3.35Å; K213-A215 VanDerWaalsContact C-N 3.33Å; K213-A215 PolarHBondContact O-N 3.47Å; K213-S216 PolarHBondContact O-N 3.26Å; K213-S216 VanDerWaalsContact O-N 3.13Å; K213-S216 PolarHBondContact O-OG 3.21Å; K213-I217 PolarHBondContact O-N 3.5Å; K213-I217 VanDerWaalsContact O-N 3.17Å; K213-S349 VanDerWaalsContact NZ-CB 3.29Å; K213-I352 HydrophobicContact CB-CB 4.32Å; K213-I352 HydrophobicContact CB-CD1 3.77Å; K213-I352 HydrophobicContact CB-CG2 4.19Å; K213-I352 HydrophobicContact CD-CB 4.28Å; K213-I352 HydrophobicContact CD-CG2 4.27Å; K213-I352 HydrophobicContact CG-CB 4.37Å; K213-I352 HydrophobicContact CG-CG2 3.98Å; K213-I352 PolarHBondContact NZ-O 3.36Å; K213-I352 WeakPolarHBondContact O-CD1 3.47Å; K213-D353 WeakPolarHBondContact CE-OD2 3.49Å; K213-D353 IonicContact NZ-OD2 3.92Å; K213-D353 PolarHBondContact NZ-OD2 2.8Å
214	I	91.7	Very high	86.6	Confident	1 Å²	1	39 Å²	39	1%	0.005	19%	0.192	C	C	.	.	H	α-helix	trans	-61.8	-39.2	178.7	-63.5	165	0	0	0	111.8	H210 Y211 I217 F244 L247 L248 L251 T256	H210-I214 VanDerWaalsContact O-CG1 3.29Å; H210-I214 WeakPolarHBondContact O-CG1 3.34Å; H210-I214 PolarHBondContact O-N 3.33Å; Y211-I214 PolarHBondContact O-N 3.39Å; I214-I217 WeakPolarHBondContact O-CG2 3.5Å; I214-F244 HydrophobicContact CB-CE2 4.22Å; I214-F244 HydrophobicContact CG2-CD2 4.24Å; I214-F244 HydrophobicContact CG2-CE2 3.79Å; I214-L247 HydrophobicContact CG2-CD2 3.76Å; I214-L247 HydrophobicContact CG2-CG 4.27Å; I214-L248 HydrophobicContact CD1-CD2 3.84Å; I214-L248 HydrophobicContact CG2-CD2 4.1Å; I214-L251 HydrophobicContact CD1-CD1 3.96Å; I214-L251 HydrophobicContact CG1-CD1 4.21Å; I214-L251 HydrophobicContact CG2-CD1 4.13Å; I214-T256 HydrophobicContact CD1-CG2 4.43Å
215	A	93.6	Very high	87.6	Confident	0 Å²	0	35.8 Å²	35.8	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-65.8	-40.9	175.3	0	0	0	0	0	111.4	L194 Y211 I212 K213 I217 L218 V219 F244	L194-A215 HydrophobicContact CD2-CB 4.02Å; L194-A215 HydrophobicContact CG-CB 4.19Å; Y211-A215 WeakPolarHBondContact O-CB 3.41Å; Y211-A215 PolarHBondContact O-N 3.31Å; I212-A215 PolarHBondContact O-N 2.88Å; K213-A215 VanDerWaalsContact C-N 3.33Å; K213-A215 PolarHBondContact O-N 3.47Å; A215-I217 PolarHBondContact O-N 3.18Å; A215-L218 PolarHBondContact O-N 3.14Å; A215-V219 WeakPolarHBondContact O-CG2 3.4Å; A215-V219 PolarHBondContact O-N 2.88Å; A215-F244 HydrophobicContact CB-CD2 4.38Å; A215-F244 HydrophobicContact CB-CE2 3.85Å; A215-F244 HydrophobicContact CB-CZ 4.39Å
216	S	94.7	Very high	88.6	Confident	0 Å²	0	30.2 Å²	30.2	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-63.4	-38.5	-177.8	74.1	0	0	0	0	113.2	F170 M177 I212 K213 V219 L220	F170-S216 WeakPolarHBondContact CE1-OG 3.38Å; M177-S216 VanDerWaalsContact CE-OG 3.29Å; M177-S216 WeakPolarHBondContact CE-OG 3.41Å; I212-S216 WeakPolarHBondContact O-CB 3.43Å; I212-S216 PolarHBondContact O-N 3.44Å; I212-S216 PolarHBondContact O-OG 2.88Å; K213-S216 PolarHBondContact O-N 3.26Å; K213-S216 VanDerWaalsContact O-N 3.13Å; K213-S216 PolarHBondContact O-OG 3.21Å; S216-V219 PolarHBondContact O-N 3.4Å; S216-L220 WeakPolarHBondContact O-CB 3.18Å; S216-L220 PolarHBondContact O-N 2.89Å
217	I	94.2	Very high	89	Confident	0 Å²	0	27.3 Å²	27.3	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-69.6	-36.3	179	-175.9	58.9	0	0	0	112.2	W133 K213 I214 A215 L220 A221 I352 L360 L361 W364	W133-I217 HydrophobicContact CH2-CD1 4.28Å; W133-I217 HydrophobicContact CH2-CG1 4.07Å; W133-I217 HydrophobicContact CZ3-CG1 4.39Å; K213-I217 PolarHBondContact O-N 3.5Å; K213-I217 VanDerWaalsContact O-N 3.17Å; I214-I217 WeakPolarHBondContact O-CG2 3.5Å; A215-I217 PolarHBondContact O-N 3.18Å; I217-L220 HydrophobicContact CD1-CD2 3.94Å; I217-L220 PolarHBondContact O-N 3.34Å; I217-A221 PolarHBondContact O-N 2.98Å; I217-A221 VanDerWaalsContact O-N 3.13Å; I217-I352 HydrophobicContact CB-CD1 3.98Å; I217-I352 HydrophobicContact CG2-CD1 4.09Å; I217-L360 HydrophobicContact CD1-CD2 4.01Å; I217-L360 HydrophobicContact CD1-CG 4.1Å; I217-L361 HydrophobicContact CD1-CD2 3.98Å; I217-W364 HydrophobicContact CB-CZ2 4.42Å; I217-W364 HydrophobicContact CD1-CD2 4.44Å; I217-W364 HydrophobicContact CD1-CG 4.05Å; I217-W364 HydrophobicContact CG1-CB 4.48Å; I217-W364 HydrophobicContact CG1-CD2 3.61Å; I217-W364 HydrophobicContact CG1-CE3 4.15Å; I217-W364 HydrophobicContact CG1-CG 3.74Å; I217-W364 HydrophobicContact CG1-CZ2 4.2Å; I217-W364 HydrophobicContact CG2-CD2 4.43Å; I217-W364 HydrophobicContact CG2-CH2 3.78Å; I217-W364 HydrophobicContact CG2-CZ2 3.68Å; I217-W364 HydrophobicContact CG2-CZ3 4.19Å
218	L	93.1	Very high	89.3	Confident	1 Å²	1	34.1 Å²	34.1	1%	0.005	16%	0.16	C	C	.	.	H	α-helix	trans	-64.3	-45.7	174.3	-174.6	65.9	0	0	0	110.6	L137 L193 A215 L220 A221 M222 L240 E243 F244	L137-L218 HydrophobicContact CD1-CD1 3.96Å; L193-L218 HydrophobicContact CD1-CD2 4.33Å; A215-L218 PolarHBondContact O-N 3.14Å; L218-L220 PolarHBondContact O-N 3.4Å; L218-A221 PolarHBondContact O-N 3.3Å; L218-M222 WeakPolarHBondContact O-CG 3.4Å; L218-M222 PolarHBondContact O-N 3.29Å; L218-L240 HydrophobicContact CD1-CD2 4.47Å; L218-L240 HydrophobicContact CD2-CD2 3.69Å; L218-L240 HydrophobicContact CG-CD2 3.67Å; L218-E243 HydrophobicContact CD1-CB 4.18Å; L218-E243 HydrophobicContact CD2-CB 4.04Å; L218-F244 HydrophobicContact CD2-CB 3.77Å
219	V	94	Very high	89.6	Confident	0 Å²	0	36.2 Å²	36.2	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-65.2	-37.5	176.3	170.3	0	0	0	0	111.9	I180 C186 A189 M190 L193 A215 S216 A221 M222 K223 L226	I180-V219 HydrophobicContact CD1-CG1 4.3Å; C186-V219 HydrophobicContact CB-CG1 3.48Å; C186-V219 VanDerWaalsContact CB-CG1 3.48Å; A189-V219 HydrophobicContact CB-CG1 4.39Å; A189-V219 HydrophobicContact CB-CG2 3.82Å; M190-V219 HydrophobicContact CG-CB 4.11Å; M190-V219 HydrophobicContact CG-CG1 4.25Å; M190-V219 HydrophobicContact CG-CG2 3.77Å; L193-V219 HydrophobicContact CD1-CG2 4.13Å; A215-V219 WeakPolarHBondContact O-CG2 3.4Å; A215-V219 PolarHBondContact O-N 2.88Å; S216-V219 PolarHBondContact O-N 3.4Å; V219-A221 VanDerWaalsContact C-N 3.3Å; V219-A221 PolarHBondContact O-N 3.33Å; V219-M222 CarbonylContact O-C 3.54Å; V219-M222 WeakPolarHBondContact O-CA 3.12Å; V219-M222 WeakPolarHBondContact O-CB 3.24Å; V219-M222 PolarHBondContact O-N 3.44Å; V219-K223 PolarHBondContact O-N 2.9Å; V219-K223 VanDerWaalsContact O-N 3.11Å; V219-L226 HydrophobicContact CG1-CD1 3.82Å
220	L	93.6	Very high	89.7	Confident	1 Å²	1	38 Å²	38	1%	0.005	18%	0.184	C	C	.	.	H	α-helix	trans	-60.6	-38.6	176	-178.1	64.8	0	0	0	111.9	M177 I180 S216 I217 L218 M222 K223 Q357 L360 L361	M177-L220 HydrophobicContact CE-CD2 3.95Å; M177-L220 HydrophobicContact SD-CB 4.05Å; M177-L220 HydrophobicContact SD-CD1 4.26Å; M177-L220 HydrophobicContact SD-CD2 3.73Å; M177-L220 HydrophobicContact SD-CG 4.23Å; I180-L220 HydrophobicContact CD1-CB 4.32Å; I180-L220 HydrophobicContact CD1-CD1 4.3Å; I180-L220 HydrophobicContact CG1-CD1 4.27Å; I180-L220 HydrophobicContact CG2-CD1 3.91Å; S216-L220 WeakPolarHBondContact O-CB 3.18Å; S216-L220 PolarHBondContact O-N 2.89Å; I217-L220 HydrophobicContact CD1-CD2 3.94Å; I217-L220 PolarHBondContact O-N 3.34Å; L218-L220 PolarHBondContact O-N 3.4Å; L220-M222 PolarHBondContact O-N 3Å; L220-K223 HydrophobicContact CD1-CD 4.38Å; L220-K223 WeakPolarHBondContact O-CB 3.36Å; L220-K223 WeakPolarHBondContact O-CG 3.25Å; L220-K223 PolarHBondContact O-N 2.89Å; L220-Q357 HydrophobicContact CD1-CG 4.31Å; L220-Q357 HydrophobicContact CD2-CG 4.08Å; L220-L360 HydrophobicContact CD2-CD2 4.42Å; L220-L361 HydrophobicContact CD2-CD2 4.16Å; L220-L361 HydrophobicContact CD2-CG 4.34Å; L220-L361 HydrophobicContact CG-CD2 4.32Å
221	A	90.5	Very high	89.8	Confident	4 Å²	4	40.4 Å²	40.4	3%	0.033	20%	0.202	C	C	.	.	H	α-helix	trans	-67.8	-19.9	173.5	0	0	0	0	0	113	W133 I217 L218 V219	W133-A221 HydrophobicContact CD2-CB 4.05Å; W133-A221 HydrophobicContact CE3-CB 3.44Å; W133-A221 VanDerWaalsContact CE3-CB 3.44Å; W133-A221 HydrophobicContact CH2-CB 3.95Å; W133-A221 HydrophobicContact CZ2-CB 4.48Å; W133-A221 HydrophobicContact CZ3-CB 3.4Å; W133-A221 VanDerWaalsContact CZ3-CB 3.4Å; I217-A221 PolarHBondContact O-N 2.98Å; I217-A221 VanDerWaalsContact O-N 3.13Å; L218-A221 PolarHBondContact O-N 3.3Å; V219-A221 VanDerWaalsContact C-N 3.3Å; V219-A221 PolarHBondContact O-N 3.33Å
222	M	87.2	Confident	89.8	Confident	7 Å²	7	41 Å²	41	3%	0.034	21%	0.207	C	C	.	.	T	Hydrogen-bonded Turn	trans	-96.5	0.6	176.2	-60.8	-140.3	39.5	0	0	114.5	R130 L218 V219 L220 D224 Y225 L226 T236 L240	R130-M222 VanDerWaalsContact NE-CE 3.3Å; R130-M222 PolarHBondContact NE-SD 2.93Å; R130-M222 PolarHBondContact NH2-SD 3.06Å; L218-M222 WeakPolarHBondContact O-CG 3.4Å; L218-M222 PolarHBondContact O-N 3.29Å; V219-M222 CarbonylContact O-C 3.54Å; V219-M222 WeakPolarHBondContact O-CA 3.12Å; V219-M222 WeakPolarHBondContact O-CB 3.24Å; V219-M222 PolarHBondContact O-N 3.44Å; L220-M222 PolarHBondContact O-N 3Å; M222-D224 PolarHBondContact O-N 2.8Å; M222-Y225 WeakPolarHBondContact O-CB 3.22Å; M222-Y225 PolarHBondContact O-N 3.45Å; M222-L226 HydrophobicContact CB-CD1 3.92Å; M222-L226 HydrophobicContact CB-CG 4.11Å; M222-L226 HydrophobicContact CE-CD2 4.48Å; M222-L226 PolarHBondContact O-N 3.26Å; M222-T236 HydrophobicContact CE-CG2 3.86Å; M222-L240 HydrophobicContact CE-CG 4.49Å; M222-L240 HydrophobicContact CG-CD2 3.91Å; M222-L240 HydrophobicContact SD-CD1 3.7Å; M222-L240 HydrophobicContact SD-CD2 3.15Å; M222-L240 WeakPolarHBondContact SD-CD2 3.36Å; M222-L240 HydrophobicContact SD-CG 3.37Å; M222-L240 WeakPolarHBondContact SD-CG 3.49Å
223	K	86.8	Confident	89.5	Confident	60 Å²	60	45.1 Å²	45.1	26%	0.261	23%	0.228	S	C	.	.	T	Hydrogen-bonded Turn	trans	-51.1	-34.9	-165.9	69.6	177.2	-168.2	172.5	0	115.4	I180 V219 L220 Y225	I180-K223 HydrophobicContact CG2-CB 3.42Å; I180-K223 VanDerWaalsContact CG2-CB 3.42Å; I180-K223 HydrophobicContact CG2-CD 4.37Å; V219-K223 PolarHBondContact O-N 2.9Å; V219-K223 VanDerWaalsContact O-N 3.11Å; L220-K223 HydrophobicContact CD1-CD 4.38Å; L220-K223 WeakPolarHBondContact O-CB 3.36Å; L220-K223 WeakPolarHBondContact O-CG 3.25Å; L220-K223 PolarHBondContact O-N 2.89Å; K223-Y225 VanDerWaalsContact C-N 3.34Å
224	D	84.5	Confident	89.1	Confident	100 Å²	100	46.9 Å²	46.9	54%	0.535	24%	0.241	S	C	.	.	T	Hydrogen-bonded Turn	trans	-85.6	-7.6	-176.6	-61.1	-34.3	0	0	0	113.2	S126 M222	S126-D224 WeakPolarHBondContact CB-OD2 3.14Å; S126-D224 PolarHBondContact OG-OD2 2.67Å; M222-D224 PolarHBondContact O-N 2.8Å
225	Y	84	Confident	88.7	Confident	94 Å²	94	53.1 Å²	53.1	37%	0.369	27%	0.27	S	S	.	.	T	Hydrogen-bonded Turn	trans	-102	-12.4	175.6	-66.2	-95.3	0	0	0	112.7	H127 R130 M222 K223	H127-Y225 WeakPolarHBondContact CA-OH 3.35Å; H127-Y225 PolarHBondContact CE1-OH 3.41Å; H127-Y225 VanDerWaalsContact CE1-OH 3.23Å; H127-Y225 AromaticContact ND1-CZ 3.61Å; H127-Y225 PolarHBondContact ND1-OH 3.48Å; H127-Y225 PolarHBondContact O-OH 2.89Å; R130-Y225 HydrophobicContact CB-CD2 4.05Å; R130-Y225 HydrophobicContact CB-CE2 3.4Å; R130-Y225 VanDerWaalsContact CB-CE2 3.4Å; R130-Y225 HydrophobicContact CG-CD2 3.82Å; R130-Y225 HydrophobicContact CG-CE2 3.47Å; R130-Y225 VanDerWaalsContact CG-CE2 3.47Å; R130-Y225 HydrophobicContact CG-CG 4.48Å; M222-Y225 WeakPolarHBondContact O-CB 3.22Å; M222-Y225 PolarHBondContact O-N 3.45Å; K223-Y225 VanDerWaalsContact C-N 3.34Å
226	L	87.3	Confident	88.3	Confident	11 Å²	11	54.9 Å²	54.9	6%	0.058	28%	0.281	C	S	.	.	S	Bend	trans	-98	130.6	179.8	-63.4	175.9	0	0	0	109.4	A189 V219 M222 K228 P232 T236	A189-L226 HydrophobicContact CB-CD1 4Å; V219-L226 HydrophobicContact CG1-CD1 3.82Å; M222-L226 HydrophobicContact CB-CD1 3.92Å; M222-L226 HydrophobicContact CB-CG 4.11Å; M222-L226 HydrophobicContact CE-CD2 4.48Å; M222-L226 PolarHBondContact O-N 3.26Å; L226-K228 PolarHBondContact O-N 2.67Å; L226-P232 HydrophobicContact CD2-CB 3.95Å; L226-T236 HydrophobicContact CD2-CG2 3.93Å
227	S	85.1	Confident	88	Confident	48 Å²	48	55 Å²	55	34%	0.336	28%	0.281	S	S	.	.			trans	-61	135	178.3	178.1	0	0	0	0	110.8	S183 G185 N229 Q230	S183-S227 PolarHBondContact OG-O 3.47Å; G185-S227 WeakPolarHBondContact CA-O 3.22Å; G185-S227 PolarHBondContact N-O 3.18Å; S227-N229 PolarHBondContact O-N 2.99Å; S227-N229 PolarHBondContact OG-N 3.14Å; S227-Q230 PolarHBondContact OG-N 3.1Å
228	K	87.4	Confident	87.4	Confident	154 Å²	154	55.1 Å²	55.1	67%	0.67	28%	0.282	S	S	*	.	S	Bend	trans	-65.6	-25.9	173.4	-68.5	-174.8	178.3	-179.5	0	112.6	V184 L226	V184-K228 VanDerWaalsContact CB-O 3.31Å; V184-K228 WeakPolarHBondContact CB-O 3.3Å; V184-K228 WeakPolarHBondContact CG2-O 3.42Å; V184-K228 PolarHBondContact N-O 3.24Å; L226-K228 PolarHBondContact O-N 2.67Å
229	N	89.4	Confident	87	Confident	137 Å²	137	57.4 Å²	57.4	73%	0.733	30%	0.297	S	S	*	.	S	Bend	trans	-118.8	-7.4	-167	-60.3	-25.4	0	0	0	114	S227	S227-N229 PolarHBondContact O-N 2.99Å; S227-N229 PolarHBondContact OG-N 3.14Å
230	Q	88.5	Confident	86.7	Confident	131 Å²	131	57.4 Å²	57.4	61%	0.612	30%	0.297	S	S	*	.	S	Bend	trans	-133.5	147.7	-175.1	-67.1	179.6	-16	0	0	110.8	G185 S227	G185-Q230 WeakPolarHBondContact CA-O 3.47Å; G185-Q230 PolarHBondContact N-O 3.18Å; S227-Q230 PolarHBondContact OG-N 3.1Å
231	P	87.4	Confident	86.3	Confident	70 Å²	70	57.4 Å²	57.4	46%	0.455	30%	0.296	S	S	.	.	P	Polyproline II helix	trans	-62.5	151.3	171	28.1	-34.2	0	0	0	110.6	Y188	Y188-P231 HydrophobicContact CD1-CB 4.3Å; Y188-P231 HydrophobicContact CD2-CB 4.38Å; Y188-P231 HydrophobicContact CG-CB 3.99Å
232	P	87.9	Confident	85.9	Confident	19 Å²	19	57.8 Å²	57.8	12%	0.123	30%	0.298	C	S	.	.	P	Polyproline II helix	trans	-64.1	154.8	175.1	27.5	-34.9	0	0	0	111.8	A189 L226 T236 I237	A189-P232 HydrophobicContact CB-CG 4.19Å; L226-P232 HydrophobicContact CD2-CB 3.95Å; P232-T236 HydrophobicContact CB-CG2 4.27Å; P232-I237 HydrophobicContact CB-CD1 3.87Å; P232-I237 HydrophobicContact CB-CG1 4.12Å; P232-I237 HydrophobicContact CG-CD1 3.23Å; P232-I237 HydrophobicContact CG-CG1 3.69Å
233	N	86.5	Confident	86	Confident	90 Å²	90	57.5 Å²	57.5	48%	0.481	30%	0.296	S	S	.	.	P	Polyproline II helix	trans	-73.3	162.8	173	67.8	26.4	0	0	0	111.7	E235 T236 I237	N233-E235 VanDerWaalsContact C-N 3.32Å; N233-E235 PolarHBondContact O-N 3.49Å; N233-T236 PolarHBondContact O-N 3.14Å; N233-T236 WeakPolarHBondContact OD1-CB 3.49Å; N233-T236 PolarHBondContact OD1-N 3Å; N233-T236 PolarHBondContact OD1-OG1 3.5Å; N233-I237 PolarHBondContact O-N 2.89Å; N233-I237 VanDerWaalsContact O-N 3.14Å
234	V	83.5	Confident	86.1	Confident	57 Å²	57	54.6 Å²	54.6	35%	0.345	28%	0.284	S	S	.	.	H	α-helix	trans	-60.5	-40.1	-176	178.6	0	0	0	0	111.9	E149 I152 Q153 T236 I237 G238	E149-V234 HydrophobicContact CB-CG1 4.27Å; E149-V234 HydrophobicContact CG-CG1 4.32Å; I152-V234 HydrophobicContact CB-CG1 4.37Å; I152-V234 HydrophobicContact CG2-CG1 4.05Å; Q153-V234 HydrophobicContact CG-CG1 4.16Å; V234-T236 PolarHBondContact O-N 2.88Å; V234-I237 PolarHBondContact O-N 3.49Å; V234-G238 PolarHBondContact O-N 3.35Å
235	E	83.6	Confident	85.9	Confident	132 Å²	132	49.9 Å²	49.9	62%	0.617	26%	0.258	S	S	*	.	H	α-helix	trans	-60.2	-44.8	178.4	-64.3	176.1	-177.1	0	0	111.6	N233 I237 G238 V239	N233-E235 VanDerWaalsContact C-N 3.32Å; N233-E235 PolarHBondContact O-N 3.49Å; E235-I237 PolarHBondContact O-N 3.02Å; E235-G238 PolarHBondContact O-N 2.92Å; E235-V239 WeakPolarHBondContact O-CG2 3.36Å; E235-V239 PolarHBondContact O-N 2.94Å
236	T	86.4	Confident	85.8	Confident	37 Å²	37	45.6 Å²	45.6	23%	0.227	24%	0.242	C	C	.	.	H	α-helix	trans	-63	-42.7	177.7	-59.5	0	0	0	0	111	M222 L226 P232 N233 V234 V239 L240	M222-T236 HydrophobicContact CE-CG2 3.86Å; L226-T236 HydrophobicContact CD2-CG2 3.93Å; P232-T236 HydrophobicContact CB-CG2 4.27Å; N233-T236 PolarHBondContact O-N 3.14Å; N233-T236 WeakPolarHBondContact OD1-CB 3.49Å; N233-T236 PolarHBondContact OD1-N 3Å; N233-T236 PolarHBondContact OD1-OG1 3.5Å; V234-T236 PolarHBondContact O-N 2.88Å; T236-V239 PolarHBondContact O-N 2.93Å; T236-L240 HydrophobicContact CG2-CD1 4.16Å; T236-L240 WeakPolarHBondContact O-CB 3.38Å; T236-L240 WeakPolarHBondContact O-CG 3.47Å; T236-L240 PolarHBondContact O-N 2.94Å
237	I	86.5	Confident	85.8	Confident	2 Å²	2	45.1 Å²	45.1	1%	0.01	24%	0.239	C	C	.	.	H	α-helix	trans	-66.7	-37.4	175.5	-63.6	-54.4	0	0	0	111.5	I152 A189 Y192 P232 N233 V234 E235 L240 S241	I152-I237 HydrophobicContact CD1-CB 4.25Å; I152-I237 HydrophobicContact CD1-CG2 3.65Å; I152-I237 HydrophobicContact CG1-CG2 3.97Å; I152-I237 HydrophobicContact CG2-CB 4.29Å; I152-I237 HydrophobicContact CG2-CG2 3.83Å; A189-I237 HydrophobicContact CB-CD1 4.13Å; Y192-I237 HydrophobicContact CD2-CD1 3.91Å; Y192-I237 HydrophobicContact CD2-CG1 3.92Å; Y192-I237 HydrophobicContact CG-CD1 4.33Å; Y192-I237 HydrophobicContact CG-CG1 4.26Å; Y192-I237 HydrophobicContact CG-CG2 4.1Å; P232-I237 HydrophobicContact CB-CD1 3.87Å; P232-I237 HydrophobicContact CB-CG1 4.12Å; P232-I237 HydrophobicContact CG-CD1 3.23Å; P232-I237 HydrophobicContact CG-CG1 3.69Å; N233-I237 PolarHBondContact O-N 2.89Å; N233-I237 VanDerWaalsContact O-N 3.14Å; V234-I237 PolarHBondContact O-N 3.49Å; E235-I237 PolarHBondContact O-N 3.02Å; I237-L240 HydrophobicContact CD1-CD1 4.39Å; I237-L240 PolarHBondContact O-N 3.4Å; I237-S241 VanDerWaalsContact O-CB 3.27Å; I237-S241 WeakPolarHBondContact O-CB 3.47Å; I237-S241 PolarHBondContact O-N 3.06Å; I237-S241 PolarHBondContact O-OG 2.88Å
238	G	82.3	Confident	85.8	Confident	2 Å²	2	42.8 Å²	42.8	2%	0.021	22%	0.223	C	C	.	.	H	α-helix	trans	-59.1	-48.6	175.9	0	0	0	0	0	111.9	I152 V234 E235 S241 Q242	I152-G238 VanDerWaalsContact CD1-CA 3.46Å; V234-G238 PolarHBondContact O-N 3.35Å; E235-G238 PolarHBondContact O-N 2.92Å; G238-S241 PolarHBondContact O-N 2.96Å; G238-Q242 PolarHBondContact O-N 3.18Å
239	V	84.4	Confident	85.3	Confident	50 Å²	50	37.5 Å²	37.5	30%	0.303	21%	0.206	S	C	.	.	H	α-helix	trans	-64	-48.5	176.1	173.5	0	0	0	0	111.3	L138 E235 T236 S241 Q242 E243	L138-V239 HydrophobicContact CD1-CG1 4.15Å; E235-V239 WeakPolarHBondContact O-CG2 3.36Å; E235-V239 PolarHBondContact O-N 2.94Å; T236-V239 PolarHBondContact O-N 2.93Å; V239-S241 VanDerWaalsContact C-N 3.27Å; V239-S241 PolarHBondContact O-N 3.32Å; V239-Q242 WeakPolarHBondContact O-CB 3.42Å; V239-Q242 PolarHBondContact O-N 3.03Å; V239-Q242 VanDerWaalsContact O-N 3.16Å; V239-E243 HydrophobicContact CG1-CG 4.39Å; V239-E243 VanDerWaalsContact CG1-OE1 3.29Å; V239-E243 WeakPolarHBondContact CG1-OE1 3.48Å; V239-E243 WeakPolarHBondContact O-CG 3.49Å; V239-E243 PolarHBondContact O-N 3.37Å
240	L	88.6	Confident	84.9	Confident	0 Å²	0	32.7 Å²	32.7	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-59.2	-38.2	178.1	-88.3	174	0	0	0	112.6	A189 L193 L218 M222 T236 I237 Q242 E243 F244	A189-L240 HydrophobicContact CB-CD1 4.08Å; L193-L240 HydrophobicContact CD1-CB 4.38Å; L193-L240 HydrophobicContact CD2-CB 3.81Å; L193-L240 WeakPolarHBondContact CD2-O 3.29Å; L218-L240 HydrophobicContact CD1-CD2 4.47Å; L218-L240 HydrophobicContact CD2-CD2 3.69Å; L218-L240 HydrophobicContact CG-CD2 3.67Å; M222-L240 HydrophobicContact CE-CG 4.49Å; M222-L240 HydrophobicContact CG-CD2 3.91Å; M222-L240 HydrophobicContact SD-CD1 3.7Å; M222-L240 HydrophobicContact SD-CD2 3.15Å; M222-L240 WeakPolarHBondContact SD-CD2 3.36Å; M222-L240 HydrophobicContact SD-CG 3.37Å; M222-L240 WeakPolarHBondContact SD-CG 3.49Å; T236-L240 HydrophobicContact CG2-CD1 4.16Å; T236-L240 WeakPolarHBondContact O-CB 3.38Å; T236-L240 WeakPolarHBondContact O-CG 3.47Å; T236-L240 PolarHBondContact O-N 2.94Å; I237-L240 HydrophobicContact CD1-CD1 4.39Å; I237-L240 PolarHBondContact O-N 3.4Å; L240-Q242 VanDerWaalsContact C-N 3.35Å; L240-E243 PolarHBondContact O-N 3.43Å; L240-F244 VanDerWaalsContact O-CB 3.25Å; L240-F244 WeakPolarHBondContact O-CB 3.4Å; L240-F244 PolarHBondContact O-N 3.43Å
241	S	85.5	Confident	84.7	Confident	0 Å²	0	26.6 Å²	26.6	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-64.7	-41.7	178	-59.6	0	0	0	0	110.7	L193 I237 G238 V239 F244 F245	L193-S241 VanDerWaalsContact CD2-CA 3.41Å; L193-S241 VanDerWaalsContact CD2-N 3.34Å; I237-S241 VanDerWaalsContact O-CB 3.27Å; I237-S241 WeakPolarHBondContact O-CB 3.47Å; I237-S241 PolarHBondContact O-N 3.06Å; I237-S241 PolarHBondContact O-OG 2.88Å; G238-S241 PolarHBondContact O-N 2.96Å; V239-S241 VanDerWaalsContact C-N 3.27Å; V239-S241 PolarHBondContact O-N 3.32Å; S241-F244 PolarHBondContact O-N 3.38Å; S241-F245 WeakPolarHBondContact O-CD2 3.38Å; S241-F245 PolarHBondContact O-N 3.29Å; S241-F245 VanDerWaalsContact O-N 3.12Å
242	Q	82.4	Confident	84.6	Confident	13 Å²	13	23.3 Å²	23.3	6%	0.061	13%	0.129	C	C	.	.	H	α-helix	trans	-62.3	-49.2	174.3	-70.9	175.2	13.1	0	0	111.8	L138 F148 G238 V239 L240 F244 F245 V246	L138-Q242 HydrophobicContact CD2-CB 4Å; F148-Q242 HydrophobicContact CD1-CG 4.47Å; F148-Q242 HydrophobicContact CD2-CG 3.68Å; F148-Q242 HydrophobicContact CE1-CG 4.34Å; F148-Q242 HydrophobicContact CE2-CG 3.53Å; F148-Q242 HydrophobicContact CG-CG 4.15Å; F148-Q242 HydrophobicContact CZ-CG 3.89Å; G238-Q242 PolarHBondContact O-N 3.18Å; V239-Q242 WeakPolarHBondContact O-CB 3.42Å; V239-Q242 PolarHBondContact O-N 3.03Å; V239-Q242 VanDerWaalsContact O-N 3.16Å; L240-Q242 VanDerWaalsContact C-N 3.35Å; Q242-F244 VanDerWaalsContact C-N 3.31Å; Q242-F244 PolarHBondContact O-N 2.85Å; Q242-F245 PolarHBondContact O-N 2.75Å; Q242-V246 WeakPolarHBondContact O-CB 3.43Å; Q242-V246 VanDerWaalsContact O-CG2 3.28Å; Q242-V246 WeakPolarHBondContact O-CG2 3.35Å; Q242-V246 PolarHBondContact O-N 3.24Å
243	E	87.6	Confident	84.2	Confident	0 Å²	0	23.2 Å²	23.2	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-59.5	-42.4	179.7	-70.5	176.3	-175.7	0	0	112.1	R130 S134 L137 L138 L218 V239 L240 L247	R130-E243 IonicContact CZ-OE1 3.83Å; R130-E243 IonicContact CZ-OE2 3.1Å; R130-E243 IonicContact NH1-OE1 2.8Å; R130-E243 PolarHBondContact NH1-OE1 3.22Å; R130-E243 IonicContact NH1-OE2 2.86Å; R130-E243 PolarHBondContact NH1-OE2 3.04Å; R130-E243 IonicContact NH2-OE1 3.45Å; R130-E243 PolarHBondContact NH2-OE1 3.14Å; R130-E243 IonicContact NH2-OE2 3.71Å; R130-E243 PolarHBondContact NH2-OE2 3.45Å; S134-E243 WeakPolarHBondContact CA-OE1 3.32Å; S134-E243 VanDerWaalsContact CB-OE1 3.24Å; S134-E243 WeakPolarHBondContact CB-OE1 3.5Å; S134-E243 PolarHBondContact OG-OE1 3.35Å; L137-E243 HydrophobicContact CB-CB 4.23Å; L137-E243 HydrophobicContact CB-CG 3.99Å; L137-E243 HydrophobicContact CD1-CB 3.81Å; L137-E243 HydrophobicContact CD1-CG 4.16Å; L138-E243 HydrophobicContact CD2-CG 3.96Å; L138-E243 HydrophobicContact CG-CG 4.16Å; L218-E243 HydrophobicContact CD1-CB 4.18Å; L218-E243 HydrophobicContact CD2-CB 4.04Å; V239-E243 HydrophobicContact CG1-CG 4.39Å; V239-E243 VanDerWaalsContact CG1-OE1 3.29Å; V239-E243 WeakPolarHBondContact CG1-OE1 3.48Å; V239-E243 WeakPolarHBondContact O-CG 3.49Å; V239-E243 PolarHBondContact O-N 3.37Å; L240-E243 PolarHBondContact O-N 3.43Å; E243-L247 VanDerWaalsContact O-CB 3.29Å; E243-L247 WeakPolarHBondContact O-CB 3.38Å; E243-L247 PolarHBondContact O-N 3.07Å
244	F	88.5	Confident	83.8	Confident	0 Å²	0	19.1 Å²	19.1	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-62.1	-44.3	177.6	-179.6	-112.5	0	0	0	112.1	L193 L194 Y197 I214 A215 L218 L240 S241 Q242 L247 L248	L193-F244 HydrophobicContact CB-CD1 4.4Å; L193-F244 HydrophobicContact CB-CG 4.5Å; L193-F244 HydrophobicContact CD2-CB 4.03Å; L193-F244 HydrophobicContact CD2-CG 4.5Å; L194-F244 HydrophobicContact CD2-CZ 4.37Å; Y197-F244 HydrophobicContact CD2-CE1 4.36Å; Y197-F244 HydrophobicContact CG-CE1 4.39Å; I214-F244 HydrophobicContact CB-CE2 4.22Å; I214-F244 HydrophobicContact CG2-CD2 4.24Å; I214-F244 HydrophobicContact CG2-CE2 3.79Å; A215-F244 HydrophobicContact CB-CD2 4.38Å; A215-F244 HydrophobicContact CB-CE2 3.85Å; A215-F244 HydrophobicContact CB-CZ 4.39Å; L218-F244 HydrophobicContact CD2-CB 3.77Å; L240-F244 VanDerWaalsContact O-CB 3.25Å; L240-F244 WeakPolarHBondContact O-CB 3.4Å; L240-F244 PolarHBondContact O-N 3.43Å; S241-F244 PolarHBondContact O-N 3.38Å; Q242-F244 VanDerWaalsContact C-N 3.31Å; Q242-F244 PolarHBondContact O-N 2.85Å; F244-L247 WeakPolarHBondContact O-CB 3.4Å; F244-L247 PolarHBondContact O-N 2.9Å; F244-L248 HydrophobicContact CD1-CD1 4.09Å; F244-L248 HydrophobicContact CE1-CD1 3.53Å; F244-L248 HydrophobicContact CE1-CG 4.28Å; F244-L248 HydrophobicContact CE2-CD1 4.41Å; F244-L248 HydrophobicContact CE2-CG 4.37Å; F244-L248 HydrophobicContact CZ-CD1 3.73Å; F244-L248 HydrophobicContact CZ-CD2 4.38Å; F244-L248 HydrophobicContact CZ-CG 4.16Å; F244-L248 WeakPolarHBondContact O-CG 3.08Å; F244-L248 PolarHBondContact O-N 3.38Å
245	F	81.7	Confident	83.9	Confident	1 Å²	1	16.4 Å²	16.4	0%	0.004	9%	0.091	C	C	.	.	H	α-helix	trans	-71.1	-39.7	-179.7	-85.6	-107.7	0	0	0	112.7	F196 I200 S241 Q242 L247 L248 S249 W262 L268	F196-F245 HydrophobicContact CD1-CD2 4.15Å; F196-F245 HydrophobicContact CD1-CE1 4.45Å; F196-F245 AromaticContact CD1-CE2 3.24Å; F196-F245 HydrophobicContact CD1-CE2 3.24Å; F196-F245 AromaticContact CD1-CZ 3.41Å; F196-F245 HydrophobicContact CD1-CZ 3.41Å; F196-F245 VanDerWaalsContact CD1-CZ 3.41Å; F196-F245 HydrophobicContact CE1-CD2 4.09Å; F196-F245 HydrophobicContact CE1-CE1 4.14Å; F196-F245 AromaticContact CE1-CE2 3.49Å; F196-F245 HydrophobicContact CE1-CE2 3.49Å; F196-F245 VanDerWaalsContact CE1-CE2 3.49Å; F196-F245 AromaticContact CE1-CZ 3.49Å; F196-F245 HydrophobicContact CE1-CZ 3.49Å; F196-F245 VanDerWaalsContact CE1-CZ 3.49Å; I200-F245 HydrophobicContact CB-CE1 4.34Å; I200-F245 HydrophobicContact CB-CZ 4.42Å; I200-F245 HydrophobicContact CD1-CD1 4.4Å; I200-F245 HydrophobicContact CD1-CE1 3.37Å; I200-F245 HydrophobicContact CD1-CE2 4.48Å; I200-F245 HydrophobicContact CD1-CZ 3.42Å; I200-F245 VanDerWaalsContact CD1-CZ 3.42Å; I200-F245 HydrophobicContact CG1-CE1 4.44Å; I200-F245 HydrophobicContact CG1-CZ 4.44Å; I200-F245 HydrophobicContact CG2-CE1 4.14Å; S241-F245 WeakPolarHBondContact O-CD2 3.38Å; S241-F245 PolarHBondContact O-N 3.29Å; S241-F245 VanDerWaalsContact O-N 3.12Å; Q242-F245 PolarHBondContact O-N 2.75Å; F245-L247 VanDerWaalsContact C-N 3.27Å; F245-L247 PolarHBondContact O-N 3.12Å; F245-L248 PolarHBondContact O-N 3.22Å; F245-S249 PolarHBondContact O-N 3.49Å; F245-S249 PolarHBondContact O-OG 2.9Å; F245-W262 AromaticContact CD1-CH2 3.8Å; F245-W262 HydrophobicContact CD1-CH2 3.8Å; F245-W262 AromaticContact CD1-CZ2 3.47Å; F245-W262 HydrophobicContact CD1-CZ2 3.47Å; F245-W262 VanDerWaalsContact CD1-CZ2 3.47Å; F245-W262 AromaticContact CE1-CH2 3.4Å; F245-W262 HydrophobicContact CE1-CH2 3.4Å; F245-W262 AromaticContact CE1-CZ2 3.59Å; F245-W262 HydrophobicContact CE1-CZ2 3.59Å; F245-W262 HydrophobicContact CG-CZ2 4.43Å; F245-W262 HydrophobicContact CZ-CH2 4.31Å; F245-L268 HydrophobicContact CB-CD1 3.61Å; F245-L268 HydrophobicContact CD1-CD1 3.57Å; F245-L268 HydrophobicContact CG-CD1 3.98Å
246	V	81.8	Confident	83.8	Confident	3 Å²	3	10.1 Å²	10.1	2%	0.018	6%	0.061	C	C	.	.	H	α-helix	trans	-56.4	-48.6	170.2	168.9	0	0	0	0	109.3	L137 R140 C141 Q242 L248 S249 I250	L137-V246 HydrophobicContact CB-CG1 4.28Å; L137-V246 HydrophobicContact CD2-CG1 3.95Å; L137-V246 WeakPolarHBondContact O-CG1 3.38Å; R140-V246 HydrophobicContact CB-CG1 3.71Å; R140-V246 HydrophobicContact CG-CG1 4.4Å; C141-V246 HydrophobicContact CB-CG2 3.75Å; Q242-V246 WeakPolarHBondContact O-CB 3.43Å; Q242-V246 VanDerWaalsContact O-CG2 3.28Å; Q242-V246 WeakPolarHBondContact O-CG2 3.35Å; Q242-V246 PolarHBondContact O-N 3.24Å; V246-L248 PolarHBondContact O-N 3.03Å; V246-S249 PolarHBondContact O-N 3.42Å; V246-S249 PolarHBondContact O-OG 2.79Å; V246-I250 HydrophobicContact CG1-CD1 3.48Å; V246-I250 VanDerWaalsContact CG1-CD1 3.48Å; V246-I250 HydrophobicContact CG1-CG1 4.41Å; V246-I250 WeakPolarHBondContact O-CG1 3.26Å; V246-I250 PolarHBondContact O-N 3.24Å; V246-I250 VanDerWaalsContact O-N 3.16Å
247	L	87.2	Confident	83.4	Confident	1 Å²	1	10.1 Å²	10.1	1%	0.005	6%	0.059	C	C	.	.	H	α-helix	trans	-59.7	-46.1	-179.2	-178.5	60.8	0	0	0	111.7	L137 I214 E243 F244 F245 S249 I250 L251 W364 M368 I371	L137-L247 HydrophobicContact CD2-CB 4.28Å; L137-L247 HydrophobicContact CD2-CD1 4.45Å; I214-L247 HydrophobicContact CG2-CD2 3.76Å; I214-L247 HydrophobicContact CG2-CG 4.27Å; E243-L247 VanDerWaalsContact O-CB 3.29Å; E243-L247 WeakPolarHBondContact O-CB 3.38Å; E243-L247 PolarHBondContact O-N 3.07Å; F244-L247 WeakPolarHBondContact O-CB 3.4Å; F244-L247 PolarHBondContact O-N 2.9Å; F245-L247 VanDerWaalsContact C-N 3.27Å; F245-L247 PolarHBondContact O-N 3.12Å; L247-S249 PolarHBondContact O-N 2.83Å; L247-I250 PolarHBondContact O-N 3.05Å; L247-I250 VanDerWaalsContact O-N 3.14Å; L247-L251 HydrophobicContact CD1-CD1 4.06Å; L247-L251 HydrophobicContact CD1-CD2 4.25Å; L247-L251 HydrophobicContact CD1-CG 3.88Å; L247-L251 HydrophobicContact CG-CD1 3.88Å; L247-L251 HydrophobicContact CG-CG 4.18Å; L247-L251 WeakPolarHBondContact O-CG 3.39Å; L247-L251 PolarHBondContact O-N 3.45Å; L247-W364 HydrophobicContact CD1-CZ3 3.89Å; L247-W364 HydrophobicContact CD2-CH2 4.2Å; L247-W364 HydrophobicContact CD2-CZ3 3.9Å; L247-W364 HydrophobicContact CG-CZ3 4.45Å; L247-M368 HydrophobicContact CD1-CE 4.1Å; L247-I371 HydrophobicContact CD1-CD1 4.38Å
248	L	84.6	Confident	82.7	Confident	0 Å²	0	10.4 Å²	10.4	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-60.2	-31.9	174.7	-72.9	-177.9	0	0	0	113.4	Y197 Y211 I214 F244 F245 V246 I250 T256 L258 W262	Y197-L248 HydrophobicContact CD2-CD1 3.84Å; Y197-L248 HydrophobicContact CE2-CD1 3.98Å; Y211-L248 HydrophobicContact CD1-CD2 4.1Å; Y211-L248 HydrophobicContact CE1-CD2 4.26Å; I214-L248 HydrophobicContact CD1-CD2 3.84Å; I214-L248 HydrophobicContact CG2-CD2 4.1Å; F244-L248 HydrophobicContact CD1-CD1 4.09Å; F244-L248 HydrophobicContact CE1-CD1 3.53Å; F244-L248 HydrophobicContact CE1-CG 4.28Å; F244-L248 HydrophobicContact CE2-CD1 4.41Å; F244-L248 HydrophobicContact CE2-CG 4.37Å; F244-L248 HydrophobicContact CZ-CD1 3.73Å; F244-L248 HydrophobicContact CZ-CD2 4.38Å; F244-L248 HydrophobicContact CZ-CG 4.16Å; F244-L248 WeakPolarHBondContact O-CG 3.08Å; F244-L248 PolarHBondContact O-N 3.38Å; F245-L248 PolarHBondContact O-N 3.22Å; V246-L248 PolarHBondContact O-N 3.03Å; L248-I250 VanDerWaalsContact C-N 3.34Å; L248-T256 HydrophobicContact CD2-CG2 4.06Å; L248-L258 HydrophobicContact CB-CD1 3.79Å; L248-L258 HydrophobicContact CD1-CD1 4.27Å; L248-L258 HydrophobicContact CD2-CD1 4.33Å; L248-L258 HydrophobicContact CG-CD1 4.36Å; L248-W262 HydrophobicContact CB-CZ2 4.49Å; L248-W262 HydrophobicContact CD1-CZ2 4.21Å
249	S	77.3	Confident	81.9	Confident	43 Å²	43	10.7 Å²	10.7	30%	0.301	6%	0.062	S	C	.	.	H	α-helix	trans	-79.4	-13.3	177.8	73.6	0	0	0	0	114.5	F245 V246 L247 F263	F245-S249 PolarHBondContact O-N 3.49Å; F245-S249 PolarHBondContact O-OG 2.9Å; V246-S249 PolarHBondContact O-N 3.42Å; V246-S249 PolarHBondContact O-OG 2.79Å; L247-S249 PolarHBondContact O-N 2.83Å; S249-F263 VanDerWaalsContact O-CD1 3.25Å; S249-F263 WeakPolarHBondContact O-CD1 2.97Å
250	I	80.7	Confident	80.8	Confident	36 Å²	36	12.2 Å²	12.2	19%	0.185	8%	0.079	C	C	.	.	H	α-helix	trans	-109.3	-33	-175.6	-63.8	171.5	0	0	0	111.7	R140 V246 L247 L248 I371 L381	R140-I250 HydrophobicContact CB-CD1 4.15Å; R140-I250 HydrophobicContact CG-CD1 3.86Å; V246-I250 HydrophobicContact CG1-CD1 3.48Å; V246-I250 VanDerWaalsContact CG1-CD1 3.48Å; V246-I250 HydrophobicContact CG1-CG1 4.41Å; V246-I250 WeakPolarHBondContact O-CG1 3.26Å; V246-I250 PolarHBondContact O-N 3.24Å; V246-I250 VanDerWaalsContact O-N 3.16Å; L247-I250 PolarHBondContact O-N 3.05Å; L247-I250 VanDerWaalsContact O-N 3.14Å; L248-I250 VanDerWaalsContact C-N 3.34Å; I250-I371 HydrophobicContact CD1-CG2 3.7Å; I250-I371 HydrophobicContact CG2-CD1 4.02Å; I250-I371 HydrophobicContact CG2-CG1 3.77Å; I250-I371 HydrophobicContact CG2-CG2 4.26Å; I250-L381 HydrophobicContact CG2-CD2 4.37Å; I250-L381 WeakPolarHBondContact O-CD2 3.42Å
251	L	85.3	Confident	79.4	Confident	3 Å²	3	15 Å²	15	2%	0.016	9%	0.094	C	C	.	.	S	Bend	trans	-59.2	144.7	174.6	-74.1	173.5	0	0	0	110.7	I214 L247 T256 W364 L381	I214-L251 HydrophobicContact CD1-CD1 3.96Å; I214-L251 HydrophobicContact CG1-CD1 4.21Å; I214-L251 HydrophobicContact CG2-CD1 4.13Å; L247-L251 HydrophobicContact CD1-CD1 4.06Å; L247-L251 HydrophobicContact CD1-CD2 4.25Å; L247-L251 HydrophobicContact CD1-CG 3.88Å; L247-L251 HydrophobicContact CG-CD1 3.88Å; L247-L251 HydrophobicContact CG-CG 4.18Å; L247-L251 WeakPolarHBondContact O-CG 3.39Å; L247-L251 PolarHBondContact O-N 3.45Å; L251-T256 HydrophobicContact CB-CG2 3.47Å; L251-T256 VanDerWaalsContact CB-CG2 3.47Å; L251-T256 HydrophobicContact CD1-CG2 4.13Å; L251-T256 HydrophobicContact CG-CG2 4.46Å; L251-W364 HydrophobicContact CD1-CH2 4.33Å; L251-W364 HydrophobicContact CD2-CH2 4.31Å; L251-L381 HydrophobicContact CD2-CD2 4.31Å
252	P	83.7	Confident	78.4	Confident	0 Å²	0	15.1 Å²	15.1	0%	0	9%	0.094	C	C	.	.			trans	-57.9	144.5	-178.8	-22.8	35	0	0	0	112	F254 I255 T256 E378 L381 L385	P252-F254 HydrophobicContact CB-CD1 3.73Å; P252-F254 HydrophobicContact CB-CD2 4.46Å; P252-F254 HydrophobicContact CB-CE1 3.27Å; P252-F254 HydrophobicContact CB-CE2 4.06Å; P252-F254 HydrophobicContact CB-CG 4.3Å; P252-F254 HydrophobicContact CB-CZ 3.46Å; P252-F254 VanDerWaalsContact CB-CZ 3.46Å; P252-F254 HydrophobicContact CG-CE1 4.05Å; P252-F254 HydrophobicContact CG-CE2 4.47Å; P252-F254 HydrophobicContact CG-CZ 3.81Å; P252-F254 PolarHBondContact O-N 3.25Å; P252-I255 HydrophobicContact CB-CG1 4.41Å; P252-I255 HydrophobicContact CG-CD1 4.2Å; P252-I255 WeakPolarHBondContact O-CB 3.42Å; P252-I255 PolarHBondContact O-N 3.3Å; P252-T256 PolarHBondContact O-N 2.85Å; P252-E378 WeakPolarHBondContact CA-OE1 3.29Å; P252-E378 HydrophobicContact CB-CG 3.99Å; P252-E378 HydrophobicContact CG-CG 4.42Å; P252-L381 HydrophobicContact CG-CD2 4.19Å; P252-L381 HydrophobicContact CG-CG 4.22Å; P252-L385 HydrophobicContact CG-CD1 3.99Å
253	S	79.3	Confident	77.2	Confident	17 Å²	17	17.7 Å²	17.7	12%	0.119	11%	0.105	C	C	.	.	H	α-helix	trans	-57	-34.1	-176.7	52.8	0	0	0	0	112.8	I255 Q257 M285 Q289 E378	S253-I255 PolarHBondContact O-N 3.09Å; S253-Q257 VanDerWaalsContact O-CA 3.29Å; S253-Q257 WeakPolarHBondContact O-CA 2.93Å; S253-Q257 PolarHBondContact O-N 3.16Å; S253-M285 WeakPolarHBondContact O-CE 3.43Å; S253-Q289 PolarHBondContact OG-OE1 2.88Å; S253-Q289 VanDerWaalsContact OG-OE1 3.06Å; S253-E378 PolarHBondContact N-OE1 3.35Å; S253-E378 PolarHBondContact OG-OE1 3.48Å
254	F	79.5	Confident	75.6	Confident	5 Å²	5	20.6 Å²	20.6	2%	0.022	12%	0.123	C	C	.	.	H	α-helix	trans	-63.2	-21.8	174.2	63.3	-101.1	0	0	0	114.6	P252 M285 K290 F293 I347	P252-F254 HydrophobicContact CB-CD1 3.73Å; P252-F254 HydrophobicContact CB-CD2 4.46Å; P252-F254 HydrophobicContact CB-CE1 3.27Å; P252-F254 HydrophobicContact CB-CE2 4.06Å; P252-F254 HydrophobicContact CB-CG 4.3Å; P252-F254 HydrophobicContact CB-CZ 3.46Å; P252-F254 VanDerWaalsContact CB-CZ 3.46Å; P252-F254 HydrophobicContact CG-CE1 4.05Å; P252-F254 HydrophobicContact CG-CE2 4.47Å; P252-F254 HydrophobicContact CG-CZ 3.81Å; P252-F254 PolarHBondContact O-N 3.25Å; F254-M285 HydrophobicContact CB-CE 4.32Å; F254-K290 HydrophobicContact CB-CG 4.34Å; F254-F293 HydrophobicContact CE1-CB 4.29Å; F254-F293 AromaticContact CE1-CD2 3.96Å; F254-F293 HydrophobicContact CE1-CD2 3.96Å; F254-F293 HydrophobicContact CE1-CG 4.22Å; F254-F293 HydrophobicContact CE2-CD1 4.41Å; F254-F293 HydrophobicContact CE2-CD2 4.07Å; F254-F293 HydrophobicContact CE2-CE2 4.18Å; F254-F293 HydrophobicContact CE2-CG 4.18Å; F254-F293 HydrophobicContact CE2-CZ 4.43Å; F254-F293 HydrophobicContact CZ-CB 4.35Å; F254-F293 HydrophobicContact CZ-CD1 4.45Å; F254-F293 AromaticContact CZ-CD2 3.38Å; F254-F293 HydrophobicContact CZ-CD2 3.38Å; F254-F293 AromaticContact CZ-CE2 3.71Å; F254-F293 HydrophobicContact CZ-CE2 3.71Å; F254-F293 AromaticContact CZ-CG 3.79Å; F254-F293 HydrophobicContact CZ-CG 3.79Å; F254-F293 HydrophobicContact CZ-CZ 4.39Å; F254-I347 HydrophobicContact CD2-CG2 3.84Å; F254-I347 HydrophobicContact CE2-CG2 3.46Å; F254-I347 VanDerWaalsContact CE2-CG2 3.46Å
255	I	85.4	Confident	73.7	Confident	0 Å²	0	25.6 Å²	25.6	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-89.1	-51.2	176.5	-55.8	-172.6	0	0	0	110.6	H210 P252 S253 Q257 I347 V350 L385	H210-I255 PolarHBondContact CD2-O 3.13Å; P252-I255 HydrophobicContact CB-CG1 4.41Å; P252-I255 HydrophobicContact CG-CD1 4.2Å; P252-I255 WeakPolarHBondContact O-CB 3.42Å; P252-I255 PolarHBondContact O-N 3.3Å; S253-I255 PolarHBondContact O-N 3.09Å; I255-Q257 VanDerWaalsContact C-N 3.35Å; I255-I347 HydrophobicContact CD1-CG2 4.14Å; I255-I347 HydrophobicContact CG1-CG2 3.99Å; I255-V350 HydrophobicContact CD1-CG2 4.07Å; I255-V350 HydrophobicContact CG2-CG2 3.65Å; I255-L385 HydrophobicContact CD1-CD1 3.65Å
256	T	81	Confident	72.4	Confident	0 Å²	0	31.6 Å²	31.6	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-79.4	-24.2	-173.2	61.3	0	0	0	0	112.5	H210 Y211 I214 L248 L251 P252 L258	H210-T256 PolarHBondContact NE2-O 3.43Å; Y211-T256 VanDerWaalsContact CE1-O 3.26Å; Y211-T256 WeakPolarHBondContact CE1-O 3.41Å; Y211-T256 VanDerWaalsContact CZ-O 3.27Å; Y211-T256 PolarHBondContact OH-O 3.32Å; I214-T256 HydrophobicContact CD1-CG2 4.43Å; L248-T256 HydrophobicContact CD2-CG2 4.06Å; L251-T256 HydrophobicContact CB-CG2 3.47Å; L251-T256 VanDerWaalsContact CB-CG2 3.47Å; L251-T256 HydrophobicContact CD1-CG2 4.13Å; L251-T256 HydrophobicContact CG-CG2 4.46Å; P252-T256 PolarHBondContact O-N 2.85Å; T256-L258 PolarHBondContact O-N 2.87Å
257	Q	77	Confident	71.1	Confident	36 Å²	36	31.6 Å²	31.6	17%	0.168	18%	0.175	C	C	.	.			trans	56.3	24.2	-174.1	-52.9	180	-9	0	0	113.4	S253 I255 F283 M285	S253-Q257 VanDerWaalsContact O-CA 3.29Å; S253-Q257 WeakPolarHBondContact O-CA 2.93Å; S253-Q257 PolarHBondContact O-N 3.16Å; I255-Q257 VanDerWaalsContact C-N 3.35Å; Q257-F283 HydrophobicContact CB-CE1 4.41Å; Q257-F283 WeakPolarHBondContact O-CD1 3.37Å; Q257-F283 WeakPolarHBondContact O-CE1 3.32Å; Q257-M285 HydrophobicContact CB-CE 4.02Å; Q257-M285 HydrophobicContact CG-CE 3.7Å
258	L	73.7	Confident	69.6	Low	9 Å²	9	33.1 Å²	33.1	5%	0.047	18%	0.182	C	C	.	.			trans	-81.3	148.5	-178.3	-65.8	167.2	0	0	0	111.2	Y197 M201 Y211 L248 T256 W262 F263	Y197-L258 HydrophobicContact CE2-CD2 3.93Å; Y197-L258 WeakPolarHBondContact OH-CD2 3.35Å; M201-L258 HydrophobicContact CE-CD2 4.12Å; M201-L258 HydrophobicContact SD-CD2 4.24Å; Y211-L258 HydrophobicContact CE1-CD2 4.18Å; Y211-L258 HydrophobicContact CE1-CG 4.45Å; Y211-L258 WeakPolarHBondContact OH-CD2 3.41Å; L248-L258 HydrophobicContact CB-CD1 3.79Å; L248-L258 HydrophobicContact CD1-CD1 4.27Å; L248-L258 HydrophobicContact CD2-CD1 4.33Å; L248-L258 HydrophobicContact CG-CD1 4.36Å; T256-L258 PolarHBondContact O-N 2.87Å; L258-W262 HydrophobicContact CB-CB 3.91Å; L258-W262 HydrophobicContact CB-CD2 4.39Å; L258-W262 HydrophobicContact CB-CG 3.94Å; L258-W262 HydrophobicContact CD1-CD2 3.82Å; L258-W262 HydrophobicContact CD1-CG 3.81Å; L258-W262 HydrophobicContact CD1-CZ2 4.25Å; L258-W262 HydrophobicContact CD2-CD2 4.36Å; L258-W262 HydrophobicContact CD2-CE3 4.33Å; L258-W262 HydrophobicContact CG-CD2 4.41Å; L258-W262 HydrophobicContact CG-CG 4.37Å; L258-F263 HydrophobicContact CB-CE2 4.3Å; L258-F263 HydrophobicContact CB-CZ 4.35Å
259	P	64.4	Low	68.3	Low	7 Å²	7	35.7 Å²	35.7	5%	0.045	19%	0.194	C	C	.	.			trans	-59.5	147.7	176	-21.9	32.4	0	0	0	111.5	I261 W262 I279	P259-I261 HydrophobicContact CB-CG2 4.22Å; P259-I261 PolarHBondContact O-N 3.35Å; P259-W262 WeakPolarHBondContact O-CB 3.49Å; P259-W262 PolarHBondContact O-N 3.31Å; P259-I279 HydrophobicContact CG-CG2 4.43Å
260	A	61.5	Low	67.3	Low	82 Å²	82	35.3 Å²	35.3	68%	0.678	19%	0.189	S	C	*	.	G	3₁₀ helix	trans	-51.2	-33.3	-176.5	0	0	0	0	0	113.8	W262 F263	A260-W262 PolarHBondContact O-N 3.08Å; A260-F263 PolarHBondContact O-N 3.34Å; A260-F263 VanDerWaalsContact O-N 3.09Å
261	I	59.8	Low	66.2	Low	58 Å²	58	34.5 Å²	34.5	30%	0.297	19%	0.186	S	C	.	.	G	3₁₀ helix	trans	-57.4	-32.1	177.2	-160.7	168	0	0	0	112	P259 F263 T264 S267 I279	P259-I261 HydrophobicContact CB-CG2 4.22Å; P259-I261 PolarHBondContact O-N 3.35Å; I261-F263 PolarHBondContact O-N 3.16Å; I261-T264 WeakPolarHBondContact O-CB 3.41Å; I261-T264 PolarHBondContact O-N 3.22Å; I261-T264 VanDerWaalsContact O-N 3.1Å; I261-T264 PolarHBondContact O-OG1 2.86Å; I261-S267 WeakPolarHBondContact O-CB 3.42Å; I261-I279 HydrophobicContact CG2-CG2 3.38Å
262	W	63	Low	64.7	Low	4 Å²	4	35.3 Å²	35.3	2%	0.015	19%	0.19	C	C	.	.	G	3₁₀ helix	trans	-57.6	-33.2	177.7	-166.2	-83.8	0	0	0	113	Y197 I200 M201 F245 L248 L258 P259 A260 T264 S267 I279	Y197-W262 HydrophobicContact CD2-CH2 4.32Å; Y197-W262 HydrophobicContact CE2-CH2 4.23Å; I200-W262 HydrophobicContact CG2-CH2 4.03Å; I200-W262 HydrophobicContact CG2-CZ3 3.97Å; M201-W262 HydrophobicContact CG-CZ3 4.43Å; M201-W262 HydrophobicContact SD-CE3 3.92Å; M201-W262 HydrophobicContact SD-CH2 4.16Å; M201-W262 HydrophobicContact SD-CZ3 3.35Å; M201-W262 WeakPolarHBondContact SD-CZ3 3.1Å; F245-W262 AromaticContact CD1-CH2 3.8Å; F245-W262 HydrophobicContact CD1-CH2 3.8Å; F245-W262 AromaticContact CD1-CZ2 3.47Å; F245-W262 HydrophobicContact CD1-CZ2 3.47Å; F245-W262 VanDerWaalsContact CD1-CZ2 3.47Å; F245-W262 AromaticContact CE1-CH2 3.4Å; F245-W262 HydrophobicContact CE1-CH2 3.4Å; F245-W262 AromaticContact CE1-CZ2 3.59Å; F245-W262 HydrophobicContact CE1-CZ2 3.59Å; F245-W262 HydrophobicContact CG-CZ2 4.43Å; F245-W262 HydrophobicContact CZ-CH2 4.31Å; L248-W262 HydrophobicContact CB-CZ2 4.49Å; L248-W262 HydrophobicContact CD1-CZ2 4.21Å; L258-W262 HydrophobicContact CB-CB 3.91Å; L258-W262 HydrophobicContact CB-CD2 4.39Å; L258-W262 HydrophobicContact CB-CG 3.94Å; L258-W262 HydrophobicContact CD1-CD2 3.82Å; L258-W262 HydrophobicContact CD1-CG 3.81Å; L258-W262 HydrophobicContact CD1-CZ2 4.25Å; L258-W262 HydrophobicContact CD2-CD2 4.36Å; L258-W262 HydrophobicContact CD2-CE3 4.33Å; L258-W262 HydrophobicContact CG-CD2 4.41Å; L258-W262 HydrophobicContact CG-CG 4.37Å; P259-W262 WeakPolarHBondContact O-CB 3.49Å; P259-W262 PolarHBondContact O-N 3.31Å; A260-W262 PolarHBondContact O-N 3.08Å; W262-T264 VanDerWaalsContact C-N 3.27Å; W262-T264 PolarHBondContact O-N 2.93Å; W262-S267 PolarHBondContact O-OG 3.03Å; W262-I279 HydrophobicContact CD2-CD1 4.35Å; W262-I279 HydrophobicContact CE3-CD1 3.35Å; W262-I279 HydrophobicContact CZ3-CD1 3.62Å
263	F	57.3	Low	63.3	Low	67 Å²	67	40.3 Å²	40.3	29%	0.294	21%	0.213	S	C	.	.	G	3₁₀ helix	trans	-82.8	-4.5	-177.2	-58.8	-80.7	0	0	0	113.4	S249 L258 A260 I261	S249-F263 VanDerWaalsContact O-CD1 3.25Å; S249-F263 WeakPolarHBondContact O-CD1 2.97Å; L258-F263 HydrophobicContact CB-CE2 4.3Å; L258-F263 HydrophobicContact CB-CZ 4.35Å; A260-F263 PolarHBondContact O-N 3.34Å; A260-F263 VanDerWaalsContact O-N 3.09Å; I261-F263 PolarHBondContact O-N 3.16Å
264	T	54.7	Low	62.1	Low	61 Å²	61	44.5 Å²	44.5	37%	0.374	23%	0.231	S	C	.	.	S	Bend	trans	-75.5	131.9	171.6	66.8	0	0	0	0	109.1	I261 W262 Q266 S267	I261-T264 WeakPolarHBondContact O-CB 3.41Å; I261-T264 PolarHBondContact O-N 3.22Å; I261-T264 VanDerWaalsContact O-N 3.1Å; I261-T264 PolarHBondContact O-OG1 2.86Å; W262-T264 VanDerWaalsContact C-N 3.27Å; W262-T264 PolarHBondContact O-N 2.93Å; T264-Q266 PolarHBondContact O-N 2.98Å; T264-S267 WeakPolarHBondContact O-CB 3.31Å; T264-S267 PolarHBondContact O-N 3.45Å; T264-S267 PolarHBondContact O-OG 3.2Å; T264-S267 PolarHBondContact OG1-N 3.34Å
265	H	49.7	Very low	60.6	Low	105 Å²	105	53.5 Å²	53.5	49%	0.486	27%	0.273	S	S	.	.	H	α-helix	trans	-53.4	-24.3	173.8	-175.9	-69.2	0	0	0	112.1	Q269	H265-Q269 VanDerWaalsContact CE1-CD 3.48Å; H265-Q269 PolarHBondContact CE1-NE2 3.24Å; H265-Q269 PolarHBondContact ND1-OE1 3.42Å
266	Q	53.1	Low	58.8	Low	126 Å²	126	59.8 Å²	59.8	59%	0.589	31%	0.306	S	S	*	.	H	α-helix	trans	-71.2	-27.8	174.5	-73.6	178.6	-10.9	0	0	113.5	T264 Q269 N270	T264-Q266 PolarHBondContact O-N 2.98Å; Q266-Q269 CarbonylContact O-C 3.41Å; Q266-Q269 PolarHBondContact O-N 3.42Å; Q266-N270 WeakPolarHBondContact O-CA 3.29Å; Q266-N270 WeakPolarHBondContact O-CB 3.24Å; Q266-N270 PolarHBondContact O-N 2.93Å; Q266-N270 PolarHBondContact O-ND2 2.93Å; Q266-N270 PolarHBondContact O-OD1 3.42Å
267	S	54.6	Low	57.2	Low	4 Å²	4	63.2 Å²	63.2	3%	0.028	32%	0.32	C	S	.	.	H	α-helix	trans	-63.1	-50.6	-175.6	69.4	0	0	0	0	112.1	I261 W262 T264 Q269 N270 V271	I261-S267 WeakPolarHBondContact O-CB 3.42Å; W262-S267 PolarHBondContact O-OG 3.03Å; T264-S267 WeakPolarHBondContact O-CB 3.31Å; T264-S267 PolarHBondContact O-N 3.45Å; T264-S267 PolarHBondContact O-OG 3.2Å; T264-S267 PolarHBondContact OG1-N 3.34Å; S267-Q269 VanDerWaalsContact C-N 3.31Å; S267-Q269 PolarHBondContact O-N 2.87Å; S267-N270 PolarHBondContact O-N 3.2Å; S267-V271 VanDerWaalsContact O-CB 3.29Å; S267-V271 WeakPolarHBondContact O-CB 3.36Å; S267-V271 WeakPolarHBondContact O-CG2 3.15Å; S267-V271 PolarHBondContact O-N 2.97Å
268	L	55.3	Low	56	Low	32 Å²	32	67.9 Å²	67.9	17%	0.168	34%	0.336	C	S	.	.	H	α-helix	trans	-64	-43.5	178.8	-159.3	85.6	0	0	0	109.6	F245 N270 I272	F245-L268 HydrophobicContact CB-CD1 3.61Å; F245-L268 HydrophobicContact CD1-CD1 3.57Å; F245-L268 HydrophobicContact CG-CD1 3.98Å; L268-N270 PolarHBondContact O-N 3.49Å; L268-I272 HydrophobicContact CD2-CD1 3.92Å; L268-I272 HydrophobicContact CG-CD1 3.7Å; L268-I272 VanDerWaalsContact O-CB 3.32Å; L268-I272 WeakPolarHBondContact O-CB 3.14Å; L268-I272 WeakPolarHBondContact O-CD1 3.41Å; L268-I272 WeakPolarHBondContact O-CG1 3.44Å; L268-I272 PolarHBondContact O-N 3.39Å
269	Q	57.2	Low	55.1	Low	54 Å²	54	68.1 Å²	68.1	25%	0.252	34%	0.337	S	S	.	.	H	α-helix	trans	-61.8	-42.1	176.3	-70.9	-172.4	-44	0	0	112.3	H265 Q266 S267 I272 Q273	H265-Q269 VanDerWaalsContact CE1-CD 3.48Å; H265-Q269 PolarHBondContact CE1-NE2 3.24Å; H265-Q269 PolarHBondContact ND1-OE1 3.42Å; Q266-Q269 CarbonylContact O-C 3.41Å; Q266-Q269 PolarHBondContact O-N 3.42Å; S267-Q269 VanDerWaalsContact C-N 3.31Å; S267-Q269 PolarHBondContact O-N 2.87Å; Q269-I272 PolarHBondContact O-N 3.33Å; Q269-Q273 WeakPolarHBondContact O-CB 3.5Å; Q269-Q273 WeakPolarHBondContact O-CG 3.48Å; Q269-Q273 PolarHBondContact O-N 3.13Å
270	N	57.7	Low	54.3	Low	36 Å²	36	76.2 Å²	76.2	19%	0.193	37%	0.372	C	S	.	.	H	α-helix	trans	-72.1	-42.5	-178.5	-69.5	-12.6	0	0	0	111.2	Q266 S267 L268 I272 Q273 H274 Y277	Q266-N270 WeakPolarHBondContact O-CA 3.29Å; Q266-N270 WeakPolarHBondContact O-CB 3.24Å; Q266-N270 PolarHBondContact O-N 2.93Å; Q266-N270 PolarHBondContact O-ND2 2.93Å; Q266-N270 PolarHBondContact O-OD1 3.42Å; S267-N270 PolarHBondContact O-N 3.2Å; L268-N270 PolarHBondContact O-N 3.49Å; N270-I272 VanDerWaalsContact C-N 3.27Å; N270-I272 PolarHBondContact O-N 2.99Å; N270-Q273 PolarHBondContact O-N 3.04Å; N270-H274 WeakPolarHBondContact O-CB 3.37Å; N270-H274 PolarHBondContact O-N 3.23Å; N270-Y277 HydrophobicContact CB-CD1 3.97Å; N270-Y277 HydrophobicContact CB-CD2 4.07Å; N270-Y277 HydrophobicContact CB-CE1 3.89Å; N270-Y277 HydrophobicContact CB-CE2 4Å; N270-Y277 HydrophobicContact CB-CG 4.05Å; N270-Y277 WeakPolarHBondContact O-CB 3.16Å
271	V	56.7	Low	53.5	Low	19 Å²	19	74 Å²	74	12%	0.115	36%	0.357	C	S	.	.	H	α-helix	trans	-57.2	-41.4	172	169.1	0	0	0	0	110.9	I200 S267 Y277 I279	I200-V271 HydrophobicContact CB-CG1 4.22Å; I200-V271 HydrophobicContact CD1-CG1 3.63Å; I200-V271 HydrophobicContact CG1-CG1 3.68Å; I200-V271 HydrophobicContact CG2-CG1 3.54Å; I200-V271 HydrophobicContact CG2-CG2 4.16Å; S267-V271 VanDerWaalsContact O-CB 3.29Å; S267-V271 WeakPolarHBondContact O-CB 3.36Å; S267-V271 WeakPolarHBondContact O-CG2 3.15Å; S267-V271 PolarHBondContact O-N 2.97Å; V271-Y277 HydrophobicContact CG2-CD1 3.79Å; V271-Y277 HydrophobicContact CG2-CE1 4.41Å; V271-I279 HydrophobicContact CG2-CD1 3.59Å; V271-I279 HydrophobicContact CG2-CG1 3.9Å
272	I	53.8	Low	52.5	Low	19 Å²	19	76.7 Å²	76.7	10%	0.097	38%	0.376	C	S	.	.	H	α-helix	trans	-83.2	-25.8	-178.8	-60.1	162.3	0	0	0	112.6	Q144 K147 F148 L268 Q269 N270	Q144-I272 HydrophobicContact CB-CG2 4.39Å; K147-I272 HydrophobicContact CB-CG2 3.95Å; K147-I272 HydrophobicContact CD-CG2 3.51Å; K147-I272 HydrophobicContact CG-CG2 4.43Å; K147-I272 PolarHBondContact NZ-O 3.46Å; F148-I272 HydrophobicContact CE2-CD1 3.52Å; F148-I272 HydrophobicContact CE2-CG1 4.13Å; F148-I272 HydrophobicContact CZ-CD1 3.52Å; F148-I272 HydrophobicContact CZ-CG1 3.98Å; L268-I272 HydrophobicContact CD2-CD1 3.92Å; L268-I272 HydrophobicContact CG-CD1 3.7Å; L268-I272 VanDerWaalsContact O-CB 3.32Å; L268-I272 WeakPolarHBondContact O-CB 3.14Å; L268-I272 WeakPolarHBondContact O-CD1 3.41Å; L268-I272 WeakPolarHBondContact O-CG1 3.44Å; L268-I272 PolarHBondContact O-N 3.39Å; Q269-I272 PolarHBondContact O-N 3.33Å; N270-I272 VanDerWaalsContact C-N 3.27Å; N270-I272 PolarHBondContact O-N 2.99Å
273	Q	54.9	Low	51.9	Low	105 Å²	105	81.4 Å²	81.4	49%	0.491	40%	0.397	S	S	.	.	H	α-helix	trans	-86	-26.9	-178.7	-78.3	177.9	1.5	0	0	113.6	Q269 N270	Q269-Q273 WeakPolarHBondContact O-CB 3.5Å; Q269-Q273 WeakPolarHBondContact O-CG 3.48Å; Q269-Q273 PolarHBondContact O-N 3.13Å; N270-Q273 PolarHBondContact O-N 3.04Å
274	H	53.3	Low	51.3	Low	105 Å²	105	86.4 Å²	86.4	49%	0.486	42%	0.421	S	S	.	.			trans	-118.9	107.6	-178.7	-65	-64.6	0	0	0	107.8	N270 N276 Y277	N270-H274 WeakPolarHBondContact O-CB 3.37Å; N270-H274 PolarHBondContact O-N 3.23Å; H274-N276 PolarHBondContact O-N 3.37Å; H274-Y277 PolarHBondContact O-N 3.01Å
275	E	48.3	Very low	51.3	Low	194 Å²	194	86.1 Å²	86.1	91%	0.907	42%	0.416	S	S	*	.	T	Hydrogen-bonded Turn	trans	-51.8	-14.1	177.6	-67.6	176.9	164.3	0	0	113.8
276	N	47.7	Very low	51.9	Low	132 Å²	132	85.6 Å²	85.6	71%	0.706	42%	0.417	S	S	*	.	T	Hydrogen-bonded Turn	trans	-120.5	14.6	179.5	-72.8	-49.6	0	0	0	114.6	H274 R278	H274-N276 PolarHBondContact O-N 3.37Å; N276-R278 PolarHBondContact O-N 2.63Å
277	Y	47.2	Very low	52.5	Low	73 Å²	73	84.8 Å²	84.8	29%	0.286	42%	0.417	S	S	.	.			trans	-75.1	98.6	178.6	-169.2	-91.5	0	0	0	110.9	N270 V271 H274 I279	N270-Y277 HydrophobicContact CB-CD1 3.97Å; N270-Y277 HydrophobicContact CB-CD2 4.07Å; N270-Y277 HydrophobicContact CB-CE1 3.89Å; N270-Y277 HydrophobicContact CB-CE2 4Å; N270-Y277 HydrophobicContact CB-CG 4.05Å; N270-Y277 WeakPolarHBondContact O-CB 3.16Å; V271-Y277 HydrophobicContact CG2-CD1 3.79Å; V271-Y277 HydrophobicContact CG2-CE1 4.41Å; H274-Y277 PolarHBondContact O-N 3.01Å; Y277-I279 HydrophobicContact CD1-CG1 4.2Å; Y277-I279 HydrophobicContact CE1-CG1 3.98Å
278	R	52.5	Low	53.7	Low	134 Å²	134	88 Å²	88	51%	0.506	43%	0.434	S	S	.	.			trans	-87.1	120	175.8	-63.2	179.3	-175.6	-172	1.6	108.5	N202 N276 K280	N202-R278 HydrophobicContact CB-CG 4.22Å; N276-R278 PolarHBondContact O-N 2.63Å; R278-K280 VanDerWaalsContact C-N 3.33Å; R278-K280 PolarHBondContact O-N 3.44Å
279	I	53.5	Low	54.9	Low	14 Å²	14	89.7 Å²	89.7	7%	0.072	44%	0.441	C	S	.	.			trans	-71.1	94.9	170.4	-68	175.8	0	0	0	107.8	P259 I261 W262 V271 Y277	P259-I279 HydrophobicContact CG-CG2 4.43Å; I261-I279 HydrophobicContact CG2-CG2 3.38Å; W262-I279 HydrophobicContact CD2-CD1 4.35Å; W262-I279 HydrophobicContact CE3-CD1 3.35Å; W262-I279 HydrophobicContact CZ3-CD1 3.62Å; V271-I279 HydrophobicContact CG2-CD1 3.59Å; V271-I279 HydrophobicContact CG2-CG1 3.9Å; Y277-I279 HydrophobicContact CD1-CG1 4.2Å; Y277-I279 HydrophobicContact CE1-CG1 3.98Å
280	K	47.8	Very low	56.3	Low	176 Å²	176	88.8 Å²	88.8	77%	0.765	44%	0.436	S	S	*	.			trans	-94.2	109.4	166	-69.7	-172.9	178.5	-176.3	0	107.5	R278	R278-K280 VanDerWaalsContact C-N 3.33Å; R278-K280 PolarHBondContact O-N 3.44Å
281	G	46.2	Very low	57.6	Low	36 Å²	36	88.5 Å²	88.5	37%	0.371	43%	0.434	S	S	.	.			trans	-147	136.6	174.8	0	0	0	0	0	109.9
282	T	38.9	Very low	59.1	Low	114 Å²	114	93.2 Å²	93.2	70%	0.699	45%	0.453	S	S	*	.			trans	-68.9	136.6	168.1	38.7	0	0	0	0	109	E284	T282-E284 VanDerWaalsContact C-N 3.32Å; T282-E284 PolarHBondContact O-N 3.24Å
283	F	49.9	Very low	60.9	Low	104 Å²	104	92.6 Å²	92.6	46%	0.456	45%	0.45	S	S	.	.			trans	-71.3	89.8	171.8	-71.1	-108	0	0	0	108	Q257	Q257-F283 HydrophobicContact CB-CE1 4.41Å; Q257-F283 WeakPolarHBondContact O-CD1 3.37Å; Q257-F283 WeakPolarHBondContact O-CE1 3.32Å
284	E	45.1	Very low	62.6	Low	172 Å²	172	87.6 Å²	87.6	80%	0.804	43%	0.427	S	S	*	.			trans	-97	83.2	163	-74.9	-177.4	-173	0	0	107.6	T282 N286	T282-E284 VanDerWaalsContact C-N 3.32Å; T282-E284 PolarHBondContact O-N 3.24Å; E284-N286 PolarHBondContact O-N 2.99Å
285	M	54.3	Low	64.4	Low	54 Å²	54	85.4 Å²	85.4	27%	0.266	42%	0.416	S	S	.	.			trans	-67.3	124.4	160.3	-82.1	-155.1	146.6	0	0	108	S253 F254 Q257 D287 K290	S253-M285 WeakPolarHBondContact O-CE 3.43Å; F254-M285 HydrophobicContact CB-CE 4.32Å; Q257-M285 HydrophobicContact CB-CE 4.02Å; Q257-M285 HydrophobicContact CG-CE 3.7Å; M285-D287 PolarHBondContact O-N 2.59Å; M285-D287 VanDerWaalsContact O-N 3.14Å; M285-K290 WeakPolarHBondContact SD-CE 3.38Å
286	N	61.6	Low	66.5	Low	95 Å²	95	77.6 Å²	77.6	51%	0.508	38%	0.383	S	S	.	.			trans	-77.3	101.6	171.2	-165.5	-10.1	0	0	0	107.3	E284 N288 Q289	E284-N286 PolarHBondContact O-N 2.99Å; N286-N288 PolarHBondContact O-N 2.49Å; N286-N288 WeakPolarHBondContact OD1-CB 3.31Å; N286-N288 PolarHBondContact OD1-N 3.03Å; N286-Q289 HydrophobicContact CB-CG 4.39Å; N286-Q289 WeakPolarHBondContact O-CB 3.29Å; N286-Q289 PolarHBondContact O-N 2.99Å
287	D	66.9	Low	68.7	Low	108 Å²	108	71.3 Å²	71.3	58%	0.578	35%	0.349	S	S	*	.	H	α-helix	trans	-49	-27.2	177.4	-71.9	-34.3	0	0	0	112.2	M285 Q289 K290 I291	M285-D287 PolarHBondContact O-N 2.59Å; M285-D287 VanDerWaalsContact O-N 3.14Å; D287-Q289 VanDerWaalsContact C-N 3.29Å; D287-Q289 PolarHBondContact O-N 3.39Å; D287-K290 WeakPolarHBondContact O-CB 3.38Å; D287-K290 PolarHBondContact O-N 3.43Å; D287-K290 VanDerWaalsContact O-N 3.15Å; D287-I291 WeakPolarHBondContact O-CG1 3.29Å; D287-I291 PolarHBondContact O-N 2.93Å; D287-I291 VanDerWaalsContact O-N 3.09Å
288	N	78.8	Confident	70.9	Confident	72 Å²	72	68 Å²	68	39%	0.385	34%	0.337	S	S	.	.	H	α-helix	trans	-56.6	-35.4	172.5	-162.8	0.3	0	0	0	113.8	N286 K292	N286-N288 PolarHBondContact O-N 2.49Å; N286-N288 WeakPolarHBondContact OD1-CB 3.31Å; N286-N288 PolarHBondContact OD1-N 3.03Å; N288-K292 VanDerWaalsContact O-CB 3.3Å; N288-K292 WeakPolarHBondContact O-CB 3.39Å; N288-K292 WeakPolarHBondContact O-CG 3.13Å; N288-K292 PolarHBondContact O-N 3.46Å; N288-K292 VanDerWaalsContact OD1-CE 3.22Å; N288-K292 WeakPolarHBondContact OD1-CE 3.4Å
289	Q	81.3	Confident	72.8	Confident	67 Å²	67	67.2 Å²	67.2	31%	0.313	34%	0.337	S	S	.	.	H	α-helix	trans	-69.5	-38.4	176.9	-73.4	177.6	-35.5	0	0	112	S253 N286 D287 K292 F293	S253-Q289 PolarHBondContact OG-OE1 2.88Å; S253-Q289 VanDerWaalsContact OG-OE1 3.06Å; N286-Q289 HydrophobicContact CB-CG 4.39Å; N286-Q289 WeakPolarHBondContact O-CB 3.29Å; N286-Q289 PolarHBondContact O-N 2.99Å; D287-Q289 VanDerWaalsContact C-N 3.29Å; D287-Q289 PolarHBondContact O-N 3.39Å; Q289-K292 PolarHBondContact O-N 2.7Å; Q289-F293 WeakPolarHBondContact O-CB 3.38Å; Q289-F293 PolarHBondContact O-N 3.35Å
290	K	86	Confident	74.7	Confident	36 Å²	36	67.2 Å²	67.2	16%	0.157	34%	0.337	C	S	.	.	H	α-helix	trans	-63	-48.1	176	-65.5	-175.4	165.5	-166.5	0	110.7	F254 M285 D287 F293 S294 Y340 E344	F254-K290 HydrophobicContact CB-CG 4.34Å; M285-K290 WeakPolarHBondContact SD-CE 3.38Å; D287-K290 WeakPolarHBondContact O-CB 3.38Å; D287-K290 PolarHBondContact O-N 3.43Å; D287-K290 VanDerWaalsContact O-N 3.15Å; K290-F293 PolarHBondContact O-N 2.94Å; K290-S294 WeakPolarHBondContact O-CB 3.42Å; K290-S294 PolarHBondContact O-N 3.22Å; K290-Y340 HydrophobicContact CB-CD1 4.01Å; K290-Y340 HydrophobicContact CB-CD2 3.81Å; K290-Y340 HydrophobicContact CB-CE1 3.88Å; K290-Y340 HydrophobicContact CB-CE2 3.65Å; K290-Y340 HydrophobicContact CB-CG 3.97Å; K290-Y340 HydrophobicContact CD-CD1 4.04Å; K290-Y340 HydrophobicContact CD-CE1 3.44Å; K290-Y340 VanDerWaalsContact CD-CE1 3.44Å; K290-Y340 HydrophobicContact CG-CD1 4.36Å; K290-Y340 HydrophobicContact CG-CE1 3.76Å; K290-Y340 HydrophobicContact CG-CE2 3.95Å; K290-Y340 WeakPolarHBondContact O-CD2 3.22Å; K290-E344 IonicContact NZ-OE1 3.23Å; K290-E344 PolarHBondContact NZ-OE1 3.06Å
291	I	84.9	Confident	76.8	Confident	29 Å²	29	58.9 Å²	58.9	15%	0.149	30%	0.3	C	S	.	.	H	α-helix	trans	-60.9	-48.3	177.5	-64.9	170.3	0	0	0	110.3	D287 F293 S294 Q295 E337	D287-I291 WeakPolarHBondContact O-CG1 3.29Å; D287-I291 PolarHBondContact O-N 2.93Å; D287-I291 VanDerWaalsContact O-N 3.09Å; I291-F293 VanDerWaalsContact C-N 3.35Å; I291-F293 PolarHBondContact O-N 3.41Å; I291-S294 WeakPolarHBondContact O-CB 3.46Å; I291-S294 PolarHBondContact O-N 3.23Å; I291-Q295 HydrophobicContact CG2-CG 4.47Å; I291-Q295 WeakPolarHBondContact O-CG 3.19Å; I291-Q295 PolarHBondContact O-N 3.23Å; I291-E337 HydrophobicContact CG1-CB 4.38Å
292	K	87.9	Confident	78.9	Confident	118 Å²	118	62.6 Å²	62.6	51%	0.513	30%	0.303	S	S	.	.	H	α-helix	trans	-60.1	-40.8	176.8	-77.9	173.8	176.5	176.1	0	113.3	N288 Q289 Q295 S296	N288-K292 VanDerWaalsContact O-CB 3.3Å; N288-K292 WeakPolarHBondContact O-CB 3.39Å; N288-K292 WeakPolarHBondContact O-CG 3.13Å; N288-K292 PolarHBondContact O-N 3.46Å; N288-K292 VanDerWaalsContact OD1-CE 3.22Å; N288-K292 WeakPolarHBondContact OD1-CE 3.4Å; Q289-K292 PolarHBondContact O-N 2.7Å; K292-Q295 PolarHBondContact O-N 3.16Å; K292-S296 PolarHBondContact O-N 3.26Å
293	F	91.2	Very high	81.4	Confident	7 Å²	7	62.5 Å²	62.5	3%	0.031	29%	0.291	C	S	.	.	H	α-helix	trans	-63.4	-46.2	176	-179.1	-93.5	0	0	0	110.9	F254 Q289 K290 I291 Q295 S296 V297 Y340 I343 I347 S382 L385	F254-F293 HydrophobicContact CE1-CB 4.29Å; F254-F293 AromaticContact CE1-CD2 3.96Å; F254-F293 HydrophobicContact CE1-CD2 3.96Å; F254-F293 HydrophobicContact CE1-CG 4.22Å; F254-F293 HydrophobicContact CE2-CD1 4.41Å; F254-F293 HydrophobicContact CE2-CD2 4.07Å; F254-F293 HydrophobicContact CE2-CE2 4.18Å; F254-F293 HydrophobicContact CE2-CG 4.18Å; F254-F293 HydrophobicContact CE2-CZ 4.43Å; F254-F293 HydrophobicContact CZ-CB 4.35Å; F254-F293 HydrophobicContact CZ-CD1 4.45Å; F254-F293 AromaticContact CZ-CD2 3.38Å; F254-F293 HydrophobicContact CZ-CD2 3.38Å; F254-F293 AromaticContact CZ-CE2 3.71Å; F254-F293 HydrophobicContact CZ-CE2 3.71Å; F254-F293 AromaticContact CZ-CG 3.79Å; F254-F293 HydrophobicContact CZ-CG 3.79Å; F254-F293 HydrophobicContact CZ-CZ 4.39Å; Q289-F293 WeakPolarHBondContact O-CB 3.38Å; Q289-F293 PolarHBondContact O-N 3.35Å; K290-F293 PolarHBondContact O-N 2.94Å; I291-F293 VanDerWaalsContact C-N 3.35Å; I291-F293 PolarHBondContact O-N 3.41Å; F293-Q295 PolarHBondContact O-N 3.19Å; F293-S296 WeakPolarHBondContact O-CA 3.3Å; F293-S296 VanDerWaalsContact O-CB 3.32Å; F293-S296 WeakPolarHBondContact O-CB 3.48Å; F293-S296 PolarHBondContact O-N 2.92Å; F293-S296 VanDerWaalsContact O-N 3.1Å; F293-V297 HydrophobicContact CD1-CG2 4.04Å; F293-V297 HydrophobicContact CE1-CG2 3.53Å; F293-V297 HydrophobicContact CZ-CG2 3.88Å; F293-V297 WeakPolarHBondContact O-CG2 3.45Å; F293-V297 PolarHBondContact O-N 3.41Å; F293-Y340 HydrophobicContact CD1-CE2 4.3Å; F293-I343 HydrophobicContact CD1-CD1 4.06Å; F293-I343 HydrophobicContact CE1-CD1 3.98Å; F293-I347 HydrophobicContact CE1-CD1 3.53Å; F293-I347 HydrophobicContact CE1-CG1 3.66Å; F293-I347 HydrophobicContact CE1-CG2 4.14Å; F293-I347 HydrophobicContact CZ-CD1 3.59Å; F293-I347 HydrophobicContact CZ-CG1 4.19Å; F293-I347 HydrophobicContact CZ-CG2 4.33Å; F293-S382 WeakPolarHBondContact CE2-O 3.36Å; F293-L385 HydrophobicContact CE2-CB 3.93Å; F293-L385 HydrophobicContact CZ-CB 4.13Å
294	S	91.7	Very high	83.1	Confident	0 Å²	0	58.1 Å²	58.1	0%	0	27%	0.272	C	S	.	.	H	α-helix	trans	-58.3	-45.3	176	-175	0	0	0	0	112.6	K290 I291 S296 V297 L298 S336 F339 Y340	K290-S294 WeakPolarHBondContact O-CB 3.42Å; K290-S294 PolarHBondContact O-N 3.22Å; I291-S294 WeakPolarHBondContact O-CB 3.46Å; I291-S294 PolarHBondContact O-N 3.23Å; S294-S296 VanDerWaalsContact C-N 3.31Å; S294-S296 PolarHBondContact O-N 2.78Å; S294-V297 PolarHBondContact O-N 3.19Å; S294-L298 PolarHBondContact O-N 2.98Å; S294-S336 WeakPolarHBondContact CB-O 3.4Å; S294-S336 WeakPolarHBondContact OG-CA 3.45Å; S294-S336 PolarHBondContact OG-O 3.04Å; S294-F339 WeakPolarHBondContact OG-CD1 3.49Å; S294-Y340 PolarHBondContact OG-N 2.76Å
295	Q	91	Very high	85.1	Confident	59 Å²	59	52.4 Å²	52.4	28%	0.276	25%	0.247	S	C	.	.	H	α-helix	trans	-57.7	-43	172.5	-72.7	171.7	-15.2	0	0	111.9	I291 K292 F293 L298 K299 D333 S336	I291-Q295 HydrophobicContact CG2-CG 4.47Å; I291-Q295 WeakPolarHBondContact O-CG 3.19Å; I291-Q295 PolarHBondContact O-N 3.23Å; K292-Q295 PolarHBondContact O-N 3.16Å; F293-Q295 PolarHBondContact O-N 3.19Å; Q295-L298 PolarHBondContact O-N 3.36Å; Q295-K299 WeakPolarHBondContact O-CB 3.33Å; Q295-K299 PolarHBondContact O-N 3.26Å; Q295-D333 PolarHBondContact NE2-OD1 2.91Å; Q295-S336 WeakPolarHBondContact CG-OG 3.4Å
296	S	92.2	Very high	86.5	Confident	29 Å²	29	51.4 Å²	51.4	20%	0.203	25%	0.251	C	S	.	.	H	α-helix	trans	-60.7	-47.3	175.7	-167.6	0	0	0	0	111.3	K292 F293 S294 L298 K299 Q300 S386	K292-S296 PolarHBondContact O-N 3.26Å; F293-S296 WeakPolarHBondContact O-CA 3.3Å; F293-S296 VanDerWaalsContact O-CB 3.32Å; F293-S296 WeakPolarHBondContact O-CB 3.48Å; F293-S296 PolarHBondContact O-N 2.92Å; F293-S296 VanDerWaalsContact O-N 3.1Å; S294-S296 VanDerWaalsContact C-N 3.31Å; S294-S296 PolarHBondContact O-N 2.78Å; S296-L298 PolarHBondContact O-N 2.9Å; S296-K299 WeakPolarHBondContact O-CB 3.45Å; S296-K299 PolarHBondContact O-N 3.42Å; S296-Q300 VanDerWaalsContact O-CG 3.31Å; S296-Q300 WeakPolarHBondContact O-CG 3.39Å; S296-Q300 PolarHBondContact O-N 2.7Å; S296-S386 WeakPolarHBondContact OG-CB 3.33Å; S296-S386 PolarHBondContact OG-OG 2.86Å
297	V	94.6	Very high	87.5	Confident	0 Å²	0	53 Å²	53	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-59.3	-47	177.6	177.7	0	0	0	0	111	F293 S294 K299 Q300 L301 F339 I343 T389 A390 I393	F293-V297 HydrophobicContact CD1-CG2 4.04Å; F293-V297 HydrophobicContact CE1-CG2 3.53Å; F293-V297 HydrophobicContact CZ-CG2 3.88Å; F293-V297 WeakPolarHBondContact O-CG2 3.45Å; F293-V297 PolarHBondContact O-N 3.41Å; S294-V297 PolarHBondContact O-N 3.19Å; V297-K299 VanDerWaalsContact C-N 3.33Å; V297-K299 PolarHBondContact O-N 2.93Å; V297-Q300 PolarHBondContact O-N 2.88Å; V297-L301 WeakPolarHBondContact O-CB 3.28Å; V297-L301 PolarHBondContact O-N 3.3Å; V297-F339 HydrophobicContact CB-CE1 4.12Å; V297-F339 HydrophobicContact CG1-CE1 3.74Å; V297-F339 HydrophobicContact CG1-CZ 4.22Å; V297-I343 HydrophobicContact CB-CD1 4.39Å; V297-I343 HydrophobicContact CG2-CD1 4.02Å; V297-T389 HydrophobicContact CG1-CG2 3.8Å; V297-T389 HydrophobicContact CG2-CG2 4.07Å; V297-A390 HydrophobicContact CG1-CB 4.49Å; V297-I393 HydrophobicContact CG1-CD1 3.95Å
298	L	92.3	Very high	88.4	Confident	4 Å²	4	48.9 Å²	48.9	2%	0.021	24%	0.237	C	C	.	.	H	α-helix	trans	-62.1	-40.4	177.6	-73.5	175.4	0	0	0	112.1	S294 Q295 S296 L301 R302 V313 F339	S294-L298 PolarHBondContact O-N 2.98Å; Q295-L298 PolarHBondContact O-N 3.36Å; S296-L298 PolarHBondContact O-N 2.9Å; L298-L301 PolarHBondContact O-N 3.18Å; L298-R302 WeakPolarHBondContact O-CB 3.43Å; L298-R302 VanDerWaalsContact O-CG 3.23Å; L298-R302 WeakPolarHBondContact O-CG 3.45Å; L298-R302 PolarHBondContact O-N 3.28Å; L298-V313 HydrophobicContact CD1-CG2 4.44Å; L298-V313 HydrophobicContact CD2-CG2 3.46Å; L298-V313 VanDerWaalsContact CD2-CG2 3.46Å; L298-F339 HydrophobicContact CD1-CB 4.24Å; L298-F339 HydrophobicContact CD1-CD1 3.95Å; L298-F339 HydrophobicContact CD1-CG 4.11Å; L298-F339 HydrophobicContact CD2-CD1 3.68Å; L298-F339 HydrophobicContact CD2-CD2 3.92Å; L298-F339 HydrophobicContact CD2-CE1 3.53Å; L298-F339 HydrophobicContact CD2-CE2 3.77Å; L298-F339 HydrophobicContact CD2-CG 3.86Å; L298-F339 HydrophobicContact CD2-CZ 3.56Å; L298-F339 HydrophobicContact CG-CD1 3.55Å; L298-F339 HydrophobicContact CG-CE1 3.65Å; L298-F339 HydrophobicContact CG-CG 4.05Å; L298-F339 HydrophobicContact CG-CZ 4.22Å
299	K	92.3	Very high	88.7	Confident	118 Å²	118	45.5 Å²	45.5	51%	0.513	22%	0.219	S	C	.	.	H	α-helix	trans	-61	-46.3	175.3	-175.4	-178.9	179.5	-179.6	0	111.4	Q295 S296 V297 R302 Y303	Q295-K299 WeakPolarHBondContact O-CB 3.33Å; Q295-K299 PolarHBondContact O-N 3.26Å; S296-K299 WeakPolarHBondContact O-CB 3.45Å; S296-K299 PolarHBondContact O-N 3.42Å; V297-K299 VanDerWaalsContact C-N 3.33Å; V297-K299 PolarHBondContact O-N 2.93Å; K299-R302 PolarHBondContact O-N 2.84Å; K299-Y303 PolarHBondContact O-N 3.39Å
300	Q	94.1	Very high	88.8	Confident	14 Å²	14	45.1 Å²	45.1	7%	0.065	22%	0.224	C	C	.	.	H	α-helix	trans	-66.8	-38.2	177.1	-56.1	-40.7	-19.9	0	0	112.1	S296 V297 Y303 I304 Y383 A390 F455	S296-Q300 VanDerWaalsContact O-CG 3.31Å; S296-Q300 WeakPolarHBondContact O-CG 3.39Å; S296-Q300 PolarHBondContact O-N 2.7Å; V297-Q300 PolarHBondContact O-N 2.88Å; Q300-Y303 WeakPolarHBondContact O-CB 3.37Å; Q300-Y303 PolarHBondContact O-N 3.35Å; Q300-I304 WeakPolarHBondContact O-CG1 3.22Å; Q300-I304 PolarHBondContact O-N 3.18Å; Q300-Y383 VanDerWaalsContact NE2-CE2 3.3Å; Q300-A390 HydrophobicContact CB-CB 3.62Å; Q300-F455 HydrophobicContact CB-CE1 4.11Å; Q300-F455 HydrophobicContact CB-CZ 4.06Å; Q300-F455 HydrophobicContact CG-CE1 4.36Å
301	L	91.3	Very high	88.7	Confident	0 Å²	0	46 Å²	46	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-65.7	-42.3	176.9	-173.5	61.4	0	0	0	111.4	V297 L298 Y303 I304 D305 I308 A309 V312 A390 I393 F394	V297-L301 WeakPolarHBondContact O-CB 3.28Å; V297-L301 PolarHBondContact O-N 3.3Å; L298-L301 PolarHBondContact O-N 3.18Å; L301-Y303 VanDerWaalsContact C-N 3.25Å; L301-Y303 PolarHBondContact O-N 3.49Å; L301-I304 PolarHBondContact O-N 3.45Å; L301-D305 CarbonylContact O-C 3.51Å; L301-D305 PolarHBondContact O-N 2.87Å; L301-I308 HydrophobicContact CD1-CG2 4.47Å; L301-A309 HydrophobicContact CB-CB 4.29Å; L301-A309 HydrophobicContact CD2-CB 4.08Å; L301-A309 HydrophobicContact CG-CB 3.83Å; L301-V312 HydrophobicContact CD2-CG2 4.37Å; L301-A390 HydrophobicContact CB-CB 4.06Å; L301-A390 WeakPolarHBondContact CD1-O 3.19Å; L301-I393 HydrophobicContact CD1-CG2 4.33Å; L301-I393 HydrophobicContact CD2-CG2 3.83Å; L301-F394 HydrophobicContact CD1-CB 3.92Å
302	R	91.6	Very high	88.7	Confident	114 Å²	114	44.6 Å²	44.6	43%	0.43	23%	0.227	S	C	.	.	H	α-helix	trans	-61.1	-34.6	173.1	-73.5	171.1	-177.3	168.5	0.5	112	L298 K299 G306 A309 E332	L298-R302 WeakPolarHBondContact O-CB 3.43Å; L298-R302 VanDerWaalsContact O-CG 3.23Å; L298-R302 WeakPolarHBondContact O-CG 3.45Å; L298-R302 PolarHBondContact O-N 3.28Å; K299-R302 PolarHBondContact O-N 2.84Å; R302-G306 PolarHBondContact O-N 2.92Å; R302-A309 HydrophobicContact CB-CB 4.31Å; R302-A309 HydrophobicContact CG-CB 3.58Å; R302-E332 IonicContact NH1-OE1 3.97Å; R302-E332 PolarHBondContact NH1-OE1 2.93Å
303	Y	90.1	Very high	88.6	Confident	113 Å²	113	39.9 Å²	39.9	44%	0.443	21%	0.208	S	C	.	.	H	α-helix	trans	-68.8	-35	176	-175.8	-103.3	0	0	0	112.7	K299 Q300 L301 Y454 F455	K299-Y303 PolarHBondContact O-N 3.39Å; Q300-Y303 WeakPolarHBondContact O-CB 3.37Å; Q300-Y303 PolarHBondContact O-N 3.35Å; L301-Y303 VanDerWaalsContact C-N 3.25Å; L301-Y303 PolarHBondContact O-N 3.49Å; Y303-Y454 HydrophobicContact CD1-CD1 4.08Å; Y303-Y454 AromaticContact CE1-CD1 3.86Å; Y303-Y454 HydrophobicContact CE1-CD1 3.86Å; Y303-Y454 HydrophobicContact CE1-CG 4.36Å; Y303-Y454 VanDerWaalsContact CE1-O 3.31Å; Y303-Y454 WeakPolarHBondContact CE1-O 3.45Å; Y303-F455 HydrophobicContact CD1-CD1 4.48Å; Y303-F455 AromaticContact CD1-CE1 3.79Å; Y303-F455 HydrophobicContact CD1-CE1 3.79Å; Y303-F455 HydrophobicContact CD1-CZ 4.26Å; Y303-F455 HydrophobicContact CE1-CE1 4.38Å
304	I	86.1	Confident	88.1	Confident	11 Å²	11	46.5 Å²	46.5	6%	0.056	24%	0.237	C	C	.	.	H	α-helix	trans	-71.9	-54.8	173.2	-61.2	166.8	0	0	0	110.5	Q300 L301 A390 I391 F394 Y454 F455	Q300-I304 WeakPolarHBondContact O-CG1 3.22Å; Q300-I304 PolarHBondContact O-N 3.18Å; L301-I304 PolarHBondContact O-N 3.45Å; I304-A390 HydrophobicContact CD1-CB 4.08Å; I304-I391 HydrophobicContact CD1-CG1 3.96Å; I304-F394 HydrophobicContact CG2-CB 4.38Å; I304-F394 HydrophobicContact CG2-CD1 4.14Å; I304-F394 HydrophobicContact CG2-CD2 3.54Å; I304-F394 HydrophobicContact CG2-CE1 4.32Å; I304-F394 HydrophobicContact CG2-CE2 3.73Å; I304-F394 HydrophobicContact CG2-CG 3.76Å; I304-F394 HydrophobicContact CG2-CZ 4.13Å; I304-Y454 HydrophobicContact CG1-CD2 4.28Å; I304-Y454 HydrophobicContact CG1-CG 4.3Å; I304-Y454 HydrophobicContact CG2-CD2 4.46Å; I304-Y454 HydrophobicContact CG2-CE2 3.99Å; I304-Y454 PolarHBondContact O-OH 3.36Å; I304-F455 HydrophobicContact CD1-CE2 3.81Å; I304-F455 HydrophobicContact CD1-CZ 3.84Å; I304-F455 HydrophobicContact CG1-CE2 3.9Å; I304-F455 HydrophobicContact CG1-CZ 3.67Å
305	D	86.6	Confident	87.6	Confident	53 Å²	53	48.9 Å²	48.9	28%	0.283	25%	0.248	S	C	.	.			trans	-157.9	110.6	180	-170.7	-47.4	0	0	0	111.6	L301 N307 I308 A309 F394	L301-D305 CarbonylContact O-C 3.51Å; L301-D305 PolarHBondContact O-N 2.87Å; D305-N307 PolarHBondContact O-N 3.21Å; D305-N307 WeakPolarHBondContact OD1-CA 3.47Å; D305-N307 WeakPolarHBondContact OD1-CB 3.42Å; D305-N307 PolarHBondContact OD1-N 3.1Å; D305-I308 HydrophobicContact CB-CB 4.08Å; D305-I308 HydrophobicContact CB-CD1 4.06Å; D305-I308 HydrophobicContact CB-CG1 4.28Å; D305-I308 PolarHBondContact OD1-N 2.86Å; D305-A309 WeakPolarHBondContact O-CB 3.16Å; D305-A309 PolarHBondContact O-N 2.9Å; D305-F394 HydrophobicContact CB-CD2 4.2Å; D305-F394 HydrophobicContact CB-CE2 3.96Å
306	G	84.5	Confident	87.2	Confident	33 Å²	33	46.2 Å²	46.2	34%	0.34	24%	0.236	S	C	.	.	H	α-helix	trans	-66.8	-28.6	-179.8	0	0	0	0	0	115.1	R302 S310	R302-G306 PolarHBondContact O-N 2.92Å; G306-S310 WeakPolarHBondContact O-CB 3.31Å; G306-S310 PolarHBondContact O-N 2.85Å; G306-S310 VanDerWaalsContact O-N 3.09Å; G306-S310 PolarHBondContact O-OG 2.96Å
307	N	82.5	Confident	86.4	Confident	129 Å²	129	45.8 Å²	45.8	69%	0.69	23%	0.231	S	C	*	.	H	α-helix	trans	-74.8	-43.3	179.3	-68.5	-32.3	0	0	0	110.6	D305 S310 S311	D305-N307 PolarHBondContact O-N 3.21Å; D305-N307 WeakPolarHBondContact OD1-CA 3.47Å; D305-N307 WeakPolarHBondContact OD1-CB 3.42Å; D305-N307 PolarHBondContact OD1-N 3.1Å; N307-S310 PolarHBondContact O-N 2.95Å; N307-S311 WeakPolarHBondContact O-CB 2.97Å; N307-S311 PolarHBondContact O-N 3.45Å; N307-S311 PolarHBondContact O-OG 2.73Å
308	I	86.2	Confident	85.4	Confident	20 Å²	20	48.4 Å²	48.4	10%	0.103	24%	0.243	C	C	.	.	H	α-helix	trans	-63.7	-46.5	174.3	-70.8	173.1	0	0	0	110	L301 D305 S310 S311 V312 F394 W397 I398	L301-I308 HydrophobicContact CD1-CG2 4.47Å; D305-I308 HydrophobicContact CB-CB 4.08Å; D305-I308 HydrophobicContact CB-CD1 4.06Å; D305-I308 HydrophobicContact CB-CG1 4.28Å; D305-I308 PolarHBondContact OD1-N 2.86Å; I308-S310 VanDerWaalsContact C-N 3.27Å; I308-S310 PolarHBondContact O-N 3.35Å; I308-S311 PolarHBondContact O-N 3.42Å; I308-V312 HydrophobicContact CG2-CG2 4.01Å; I308-V312 VanDerWaalsContact O-CG2 3.27Å; I308-V312 WeakPolarHBondContact O-CG2 3.39Å; I308-V312 PolarHBondContact O-N 3.24Å; I308-F394 HydrophobicContact CD1-CD2 3.63Å; I308-F394 HydrophobicContact CD1-CE2 3.49Å; I308-F394 VanDerWaalsContact CD1-CE2 3.49Å; I308-W397 HydrophobicContact CG2-CB 4.13Å; I308-W397 HydrophobicContact CG2-CG 3.82Å; I308-I398 HydrophobicContact CD1-CG2 3.68Å
309	A	85.2	Confident	84.3	Confident	1 Å²	1	48.4 Å²	48.4	1%	0.008	24%	0.243	C	C	.	.	H	α-helix	trans	-54	-46.1	176.6	0	0	0	0	0	112	L301 R302 D305 S311 V313	L301-A309 HydrophobicContact CB-CB 4.29Å; L301-A309 HydrophobicContact CD2-CB 4.08Å; L301-A309 HydrophobicContact CG-CB 3.83Å; R302-A309 HydrophobicContact CB-CB 4.31Å; R302-A309 HydrophobicContact CG-CB 3.58Å; D305-A309 WeakPolarHBondContact O-CB 3.16Å; D305-A309 PolarHBondContact O-N 2.9Å; A309-S311 VanDerWaalsContact C-N 3.35Å; A309-S311 PolarHBondContact O-N 3.39Å; A309-V313 VanDerWaalsContact O-CG2 3.3Å; A309-V313 WeakPolarHBondContact O-CG2 3.37Å; A309-V313 PolarHBondContact O-N 3.21Å; A309-V313 VanDerWaalsContact O-N 3.08Å
310	S	83.3	Confident	83.1	Confident	60 Å²	60	45.9 Å²	45.9	42%	0.42	23%	0.232	S	C	.	.	H	α-helix	trans	-65.2	-37.9	177.4	-58.1	0	0	0	0	112.4	G306 N307 I308 K314	G306-S310 WeakPolarHBondContact O-CB 3.31Å; G306-S310 PolarHBondContact O-N 2.85Å; G306-S310 VanDerWaalsContact O-N 3.09Å; G306-S310 PolarHBondContact O-OG 2.96Å; N307-S310 PolarHBondContact O-N 2.95Å; I308-S310 VanDerWaalsContact C-N 3.27Å; I308-S310 PolarHBondContact O-N 3.35Å; S310-K314 WeakPolarHBondContact O-CB 3.34Å; S310-K314 VanDerWaalsContact O-CG 3.26Å; S310-K314 WeakPolarHBondContact O-CG 3.47Å; S310-K314 PolarHBondContact O-N 3.09Å
311	S	83.1	Confident	81.6	Confident	53 Å²	53	48.4 Å²	48.4	37%	0.371	25%	0.246	S	C	.	.	H	α-helix	trans	-70.5	-42.8	-179.8	-56.3	0	0	0	0	112	N307 I308 A309 K314 Q315	N307-S311 WeakPolarHBondContact O-CB 2.97Å; N307-S311 PolarHBondContact O-N 3.45Å; N307-S311 PolarHBondContact O-OG 2.73Å; I308-S311 PolarHBondContact O-N 3.42Å; A309-S311 VanDerWaalsContact C-N 3.35Å; A309-S311 PolarHBondContact O-N 3.39Å; S311-K314 PolarHBondContact O-N 2.75Å; S311-Q315 WeakPolarHBondContact O-CB 3.36Å; S311-Q315 PolarHBondContact O-N 2.94Å
312	V	84.7	Confident	80.3	Confident	0 Å²	0	51.1 Å²	51.1	0%	0	26%	0.26	C	S	.	.	H	α-helix	trans	-60.7	-48.7	174.7	178.7	0	0	0	0	109.9	L301 I308 K314 Q315 V316 F339 F342 I393 W397	L301-V312 HydrophobicContact CD2-CG2 4.37Å; I308-V312 HydrophobicContact CG2-CG2 4.01Å; I308-V312 VanDerWaalsContact O-CG2 3.27Å; I308-V312 WeakPolarHBondContact O-CG2 3.39Å; I308-V312 PolarHBondContact O-N 3.24Å; V312-K314 PolarHBondContact O-N 3.39Å; V312-Q315 PolarHBondContact O-N 3.31Å; V312-V316 HydrophobicContact CG1-CG2 4.34Å; V312-V316 VanDerWaalsContact O-CG2 3.31Å; V312-V316 WeakPolarHBondContact O-CG2 3.2Å; V312-V316 PolarHBondContact O-N 3.48Å; V312-F339 HydrophobicContact CG1-CE2 3.79Å; V312-F342 HydrophobicContact CG1-CE1 4.2Å; V312-I393 HydrophobicContact CG1-CG2 4.15Å; V312-I393 HydrophobicContact CG2-CG2 3.97Å; V312-W397 HydrophobicContact CB-CE3 4.34Å; V312-W397 HydrophobicContact CB-CZ3 4.22Å; V312-W397 HydrophobicContact CG1-CZ3 4.46Å; V312-W397 HydrophobicContact CG2-CD2 3.52Å; V312-W397 HydrophobicContact CG2-CE3 3.41Å; V312-W397 VanDerWaalsContact CG2-CE3 3.41Å; V312-W397 HydrophobicContact CG2-CG 4.07Å; V312-W397 HydrophobicContact CG2-CH2 4.2Å; V312-W397 HydrophobicContact CG2-CZ2 4.33Å; V312-W397 HydrophobicContact CG2-CZ3 3.76Å
313	V	85.5	Confident	78.5	Confident	20 Å²	20	51 Å²	51	12%	0.121	27%	0.268	C	S	.	.	H	α-helix	trans	-60.4	-46	178.8	171.1	0	0	0	0	111	L298 A309 Q315 V316 L317 F339	L298-V313 HydrophobicContact CD1-CG2 4.44Å; L298-V313 HydrophobicContact CD2-CG2 3.46Å; L298-V313 VanDerWaalsContact CD2-CG2 3.46Å; A309-V313 VanDerWaalsContact O-CG2 3.3Å; A309-V313 WeakPolarHBondContact O-CG2 3.37Å; A309-V313 PolarHBondContact O-N 3.21Å; A309-V313 VanDerWaalsContact O-N 3.08Å; V313-Q315 VanDerWaalsContact C-N 3.32Å; V313-Q315 PolarHBondContact O-N 3.15Å; V313-V316 PolarHBondContact O-N 2.9Å; V313-L317 HydrophobicContact CG1-CD1 3.81Å; V313-L317 HydrophobicContact CG1-CG 4.2Å; V313-L317 WeakPolarHBondContact O-CB 3.3Å; V313-L317 VanDerWaalsContact O-CG 3.27Å; V313-L317 WeakPolarHBondContact O-CG 3.22Å; V313-L317 PolarHBondContact O-N 3.29Å; V313-F339 HydrophobicContact CG2-CD2 4.42Å
314	K	81.1	Confident	76.7	Confident	146 Å²	146	51.6 Å²	51.6	64%	0.635	28%	0.283	S	S	*	.	H	α-helix	trans	-58.2	-43.4	175.6	-77.6	176.3	-179.4	-176	0	112.2	S310 S311 V312 L317 F318	S310-K314 WeakPolarHBondContact O-CB 3.34Å; S310-K314 VanDerWaalsContact O-CG 3.26Å; S310-K314 WeakPolarHBondContact O-CG 3.47Å; S310-K314 PolarHBondContact O-N 3.09Å; S311-K314 PolarHBondContact O-N 2.75Å; V312-K314 PolarHBondContact O-N 3.39Å; K314-L317 PolarHBondContact O-N 2.73Å; K314-F318 VanDerWaalsContact O-CB 3.24Å; K314-F318 WeakPolarHBondContact O-CB 3.4Å; K314-F318 PolarHBondContact O-N 2.89Å
315	Q	81.1	Confident	75	Confident	49 Å²	49	53.2 Å²	53.2	23%	0.229	29%	0.291	C	S	.	.	H	α-helix	trans	-63.3	-45	177.1	-171.7	64.8	32.3	0	0	111.3	S311 V312 V313 L317 F318 V319 W397 L431	S311-Q315 WeakPolarHBondContact O-CB 3.36Å; S311-Q315 PolarHBondContact O-N 2.94Å; V312-Q315 PolarHBondContact O-N 3.31Å; V313-Q315 VanDerWaalsContact C-N 3.32Å; V313-Q315 PolarHBondContact O-N 3.15Å; Q315-L317 VanDerWaalsContact C-N 3.34Å; Q315-L317 PolarHBondContact O-N 3.43Å; Q315-F318 PolarHBondContact O-N 3.14Å; Q315-V319 HydrophobicContact CG-CG2 4.49Å; Q315-V319 WeakPolarHBondContact O-CB 3.18Å; Q315-V319 WeakPolarHBondContact O-CG2 3.31Å; Q315-V319 PolarHBondContact O-N 3.05Å; Q315-W397 HydrophobicContact CB-CH2 3.8Å; Q315-W397 HydrophobicContact CB-CZ3 4.31Å; Q315-W397 HydrophobicContact CG-CH2 4.2Å; Q315-L431 HydrophobicContact CG-CD2 4.36Å
316	V	81.8	Confident	73.3	Confident	3 Å²	3	55.6 Å²	55.6	2%	0.018	31%	0.312	C	S	.	.	H	α-helix	trans	-64.4	-39.3	178.7	177.2	0	0	0	0	111.4	V312 V313 K320 I338 F339 F342 L431	V312-V316 HydrophobicContact CG1-CG2 4.34Å; V312-V316 VanDerWaalsContact O-CG2 3.31Å; V312-V316 WeakPolarHBondContact O-CG2 3.2Å; V312-V316 PolarHBondContact O-N 3.48Å; V313-V316 PolarHBondContact O-N 2.9Å; V316-K320 WeakPolarHBondContact O-CG 3.27Å; V316-K320 PolarHBondContact O-N 3.31Å; V316-I338 HydrophobicContact CG1-CG2 3.76Å; V316-F339 HydrophobicContact CG2-CD2 4.39Å; V316-F342 HydrophobicContact CG1-CB 3.87Å; V316-F342 HydrophobicContact CG2-CB 3.93Å; V316-F342 HydrophobicContact CG2-CD1 3.86Å; V316-F342 HydrophobicContact CG2-CD2 4.19Å; V316-F342 HydrophobicContact CG2-CE1 4.43Å; V316-F342 HydrophobicContact CG2-CG 3.7Å; V316-L431 HydrophobicContact CG2-CD2 4.48Å
317	L	77.1	Confident	71.3	Confident	20 Å²	20	59.9 Å²	59.9	11%	0.105	33%	0.327	C	S	.	.	H	α-helix	trans	-67.4	-45.1	176.2	-71	174.4	0	0	0	112.3	V313 K314 Q315 V319 K320 D321 I322 I325 I338	V313-L317 HydrophobicContact CG1-CD1 3.81Å; V313-L317 HydrophobicContact CG1-CG 4.2Å; V313-L317 WeakPolarHBondContact O-CB 3.3Å; V313-L317 VanDerWaalsContact O-CG 3.27Å; V313-L317 WeakPolarHBondContact O-CG 3.22Å; V313-L317 PolarHBondContact O-N 3.29Å; K314-L317 PolarHBondContact O-N 2.73Å; Q315-L317 VanDerWaalsContact C-N 3.34Å; Q315-L317 PolarHBondContact O-N 3.43Å; L317-V319 VanDerWaalsContact C-N 3.29Å; L317-V319 PolarHBondContact O-N 3.41Å; L317-K320 CarbonylContact O-C 3.59Å; L317-K320 WeakPolarHBondContact O-CA 3.44Å; L317-K320 PolarHBondContact O-N 3.22Å; L317-D321 PolarHBondContact O-N 3.13Å; L317-I322 HydrophobicContact CD2-CB 4.35Å; L317-I322 HydrophobicContact CD2-CD1 4.41Å; L317-I322 HydrophobicContact CD2-CG2 4.28Å; L317-I322 PolarHBondContact O-N 2.87Å; L317-I322 VanDerWaalsContact O-N 3.08Å; L317-I325 HydrophobicContact CD1-CD1 3.8Å; L317-I325 HydrophobicContact CD1-CG1 4.15Å; L317-I325 HydrophobicContact CD2-CD1 3.82Å; L317-I325 HydrophobicContact CG-CD1 4.47Å; L317-I338 HydrophobicContact CD2-CB 4.47Å; L317-I338 HydrophobicContact CD2-CD1 3.69Å; L317-I338 HydrophobicContact CD2-CG2 4.03Å
318	F	72.7	Confident	69.5	Low	56 Å²	56	60 Å²	60	25%	0.246	33%	0.327	C	S	.	.	H	α-helix	trans	-55.6	-48.8	175.6	176.7	-98	0	0	0	110.3	K314 Q315 K320 D321 I408	K314-F318 VanDerWaalsContact O-CB 3.24Å; K314-F318 WeakPolarHBondContact O-CB 3.4Å; K314-F318 PolarHBondContact O-N 2.89Å; Q315-F318 PolarHBondContact O-N 3.14Å; F318-K320 PolarHBondContact O-N 3.46Å; F318-K320 VanDerWaalsContact O-N 3.14Å; F318-D321 PolarHBondContact O-N 3.19Å; F318-I408 HydrophobicContact CE2-CG1 4.36Å; F318-I408 HydrophobicContact CE2-CG2 4.04Å; F318-I408 HydrophobicContact CZ-CG1 4.24Å
319	V	68.4	Low	67.4	Low	3 Å²	3	63.6 Å²	63.6	2%	0.018	36%	0.36	C	S	.	.	H	α-helix	trans	-66.2	-18.9	179.4	179.9	0	0	0	0	112.8	Q315 L317 S424 E427 I428	Q315-V319 HydrophobicContact CG-CG2 4.49Å; Q315-V319 WeakPolarHBondContact O-CB 3.18Å; Q315-V319 WeakPolarHBondContact O-CG2 3.31Å; Q315-V319 PolarHBondContact O-N 3.05Å; L317-V319 VanDerWaalsContact C-N 3.29Å; L317-V319 PolarHBondContact O-N 3.41Å; V319-S424 VanDerWaalsContact CG1-O 3.25Å; V319-S424 WeakPolarHBondContact CG1-O 3.4Å; V319-S424 VanDerWaalsContact O-CA 3.22Å; V319-S424 WeakPolarHBondContact O-CA 3.11Å; V319-S424 WeakPolarHBondContact O-CB 3.33Å; V319-E427 HydrophobicContact CB-CB 4.39Å; V319-E427 HydrophobicContact CG1-CB 3.44Å; V319-E427 VanDerWaalsContact CG1-CB 3.44Å; V319-E427 HydrophobicContact CG2-CB 4.07Å; V319-I428 HydrophobicContact CB-CD1 4.39Å; V319-I428 HydrophobicContact CB-CG1 4.08Å; V319-I428 HydrophobicContact CG1-CB 3.93Å; V319-I428 HydrophobicContact CG1-CD1 3.7Å; V319-I428 HydrophobicContact CG1-CG1 3.36Å
320	K	68.1	Low	65.7	Low	66 Å²	66	70.8 Å²	70.8	29%	0.287	40%	0.398	S	S	.	.	T	Hydrogen-bonded Turn	trans	-91	8.4	173.6	-74.4	-61.4	-164.8	-171.7	0	114	V316 L317 F318 I322 I338 I428	V316-K320 WeakPolarHBondContact O-CG 3.27Å; V316-K320 PolarHBondContact O-N 3.31Å; L317-K320 CarbonylContact O-C 3.59Å; L317-K320 WeakPolarHBondContact O-CA 3.44Å; L317-K320 PolarHBondContact O-N 3.22Å; F318-K320 PolarHBondContact O-N 3.46Å; F318-K320 VanDerWaalsContact O-N 3.14Å; K320-I322 VanDerWaalsContact C-N 3.28Å; K320-I322 HydrophobicContact CB-CD1 3.99Å; K320-I322 HydrophobicContact CB-CG1 4.22Å; K320-I322 PolarHBondContact O-N 3.45Å; K320-I338 HydrophobicContact CB-CG2 4.41Å; K320-I338 HydrophobicContact CG-CG2 3.81Å; K320-I428 HydrophobicContact CD-CD1 3.48Å; K320-I428 VanDerWaalsContact CD-CD1 3.48Å; K320-I428 HydrophobicContact CG-CD1 3.9Å
321	D	62.4	Low	64.5	Low	66 Å²	66	68.7 Å²	68.7	35%	0.353	38%	0.382	S	S	.	.	T	Hydrogen-bonded Turn	trans	56.3	38.4	-172.4	-73	-42.4	0	0	0	113	L317 F318 R420	L317-D321 PolarHBondContact O-N 3.13Å; F318-D321 PolarHBondContact O-N 3.19Å; D321-R420 WeakPolarHBondContact OD2-CB 3.31Å; D321-R420 WeakPolarHBondContact OD2-CG 3.39Å
322	I	63.8	Low	63.8	Low	58 Å²	58	70.9 Å²	70.9	30%	0.297	39%	0.386	S	S	.	.			trans	-106.4	88	176.5	-62.1	170.2	0	0	0	107.7	L317 K320 T324 I325 I338	L317-I322 HydrophobicContact CD2-CB 4.35Å; L317-I322 HydrophobicContact CD2-CD1 4.41Å; L317-I322 HydrophobicContact CD2-CG2 4.28Å; L317-I322 PolarHBondContact O-N 2.87Å; L317-I322 VanDerWaalsContact O-N 3.08Å; K320-I322 VanDerWaalsContact C-N 3.28Å; K320-I322 HydrophobicContact CB-CD1 3.99Å; K320-I322 HydrophobicContact CB-CG1 4.22Å; K320-I322 PolarHBondContact O-N 3.45Å; I322-T324 VanDerWaalsContact C-N 3.32Å; I322-T324 PolarHBondContact O-N 3.28Å; I322-I325 HydrophobicContact CG2-CD1 4.18Å; I322-I325 HydrophobicContact CG2-CG1 3.93Å; I322-I338 HydrophobicContact CD1-CD1 3.22Å; I322-I338 HydrophobicContact CD1-CG1 4.05Å
323	D	53.7	Low	63.1	Low	112 Å²	112	75.5 Å²	75.5	60%	0.599	41%	0.411	S	S	*	.			trans	-69.9	-20.4	-164	-85.9	-32.4	0	0	0	115.1
324	T	53.3	Low	62.4	Low	124 Å²	124	78.5 Å²	78.5	76%	0.761	43%	0.425	S	S	*	.			trans	-175.5	119.1	178.5	5.9	0	0	0	0	108.8	I322	I322-T324 VanDerWaalsContact C-N 3.32Å; I322-T324 PolarHBondContact O-N 3.28Å
325	I	50.5	Low	62.1	Low	46 Å²	46	72.5 Å²	72.5	24%	0.236	40%	0.402	C	S	.	.			trans	-100.7	109.5	167.1	-10.9	-176.2	0	0	0	106.5	L317 I322 E331 C335	L317-I325 HydrophobicContact CD1-CD1 3.8Å; L317-I325 HydrophobicContact CD1-CG1 4.15Å; L317-I325 HydrophobicContact CD2-CD1 3.82Å; L317-I325 HydrophobicContact CG-CD1 4.47Å; I322-I325 HydrophobicContact CG2-CD1 4.18Å; I322-I325 HydrophobicContact CG2-CG1 3.93Å; I325-E331 WeakPolarHBondContact CA-OE1 3.25Å; I325-E331 HydrophobicContact CB-CG 4.06Å; I325-E331 VanDerWaalsContact CB-OE1 3.29Å; I325-E331 WeakPolarHBondContact CB-OE1 3.41Å; I325-E331 VanDerWaalsContact CB-OE2 3.3Å; I325-E331 WeakPolarHBondContact CB-OE2 3.31Å; I325-E331 HydrophobicContact CG2-CB 4.18Å; I325-E331 HydrophobicContact CG2-CG 3.42Å; I325-E331 VanDerWaalsContact CG2-CG 3.42Å; I325-E331 WeakPolarHBondContact CG2-OE1 3.24Å; I325-C335 WeakPolarHBondContact CD1-SG 3.27Å
326	S	50.5	Low	62.2	Low	103 Å²	103	70.4 Å²	70.4	72%	0.72	39%	0.392	S	S	*	.			trans	-88.3	0.5	-163.4	51.8	0	0	0	0	114.8	E331	S326-E331 PolarHBondContact N-OE1 2.93Å
327	N	43.1	Very low	62.2	Low	122 Å²	122	75.8 Å²	75.8	65%	0.652	42%	0.417	S	S	*	.			trans	-152.8	82	-173.2	-85.7	-32.7	0	0	0	113.5	A329 E331	N327-A329 PolarHBondContact O-N 3.14Å; N327-E331 VanDerWaalsContact CA-OE1 3.32Å; N327-E331 WeakPolarHBondContact CA-OE1 3.44Å; N327-E331 VanDerWaalsContact N-CD 3.35Å; N327-E331 PolarHBondContact N-OE1 3.07Å; N327-E331 PolarHBondContact N-OE2 3.49Å; N327-E331 WeakPolarHBondContact O-CG 3.06Å
328	L	45.1	Very low	62.4	Low	132 Å²	132	75.8 Å²	75.8	69%	0.691	42%	0.417	S	S	*	.	T	Hydrogen-bonded Turn	trans	-48.4	-19.7	-171.5	-94.8	84.5	0	0	0	118.2	E331	L328-E331 WeakPolarHBondContact CA-OE2 3.34Å; L328-E331 PolarHBondContact N-OE2 3.3Å; L328-E331 PolarHBondContact O-N 2.8Å
329	A	41.7	Very low	63.2	Low	96 Å²	96	73.2 Å²	73.2	79%	0.793	41%	0.406	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.7	-31.2	-169.4	0	0	0	0	0	115.2	N327	N327-A329 PolarHBondContact O-N 3.14Å
330	N	48.1	Very low	64.1	Low	151 Å²	151	73.5 Å²	73.5	81%	0.807	41%	0.407	S	S	*	.	T	Hydrogen-bonded Turn	trans	-96.5	2.1	170.6	-76.8	-10.8	0	0	0	111.8
331	E	59.5	Low	65	Low	17 Å²	17	73 Å²	73	8%	0.079	41%	0.409	C	S	.	.	T	Hydrogen-bonded Turn	trans	-101.7	-10.4	-168.7	-64.9	172.8	173.6	0	0	112.9	I325 S326 N327 L328 D333 I334 C335	I325-E331 WeakPolarHBondContact CA-OE1 3.25Å; I325-E331 HydrophobicContact CB-CG 4.06Å; I325-E331 VanDerWaalsContact CB-OE1 3.29Å; I325-E331 WeakPolarHBondContact CB-OE1 3.41Å; I325-E331 VanDerWaalsContact CB-OE2 3.3Å; I325-E331 WeakPolarHBondContact CB-OE2 3.31Å; I325-E331 HydrophobicContact CG2-CB 4.18Å; I325-E331 HydrophobicContact CG2-CG 3.42Å; I325-E331 VanDerWaalsContact CG2-CG 3.42Å; I325-E331 WeakPolarHBondContact CG2-OE1 3.24Å; S326-E331 PolarHBondContact N-OE1 2.93Å; N327-E331 VanDerWaalsContact CA-OE1 3.32Å; N327-E331 WeakPolarHBondContact CA-OE1 3.44Å; N327-E331 VanDerWaalsContact N-CD 3.35Å; N327-E331 PolarHBondContact N-OE1 3.07Å; N327-E331 PolarHBondContact N-OE2 3.49Å; N327-E331 WeakPolarHBondContact O-CG 3.06Å; L328-E331 WeakPolarHBondContact CA-OE2 3.34Å; L328-E331 PolarHBondContact N-OE2 3.3Å; L328-E331 PolarHBondContact O-N 2.8Å; E331-D333 VanDerWaalsContact C-N 3.32Å; E331-D333 PolarHBondContact O-N 2.95Å; E331-I334 PolarHBondContact O-N 2.69Å; E331-C335 WeakPolarHBondContact O-CB 3.41Å; E331-C335 PolarHBondContact O-N 3.13Å; E331-C335 PolarHBondContact O-SG 2.95Å
332	E	67.5	Low	66.2	Low	99 Å²	99	70 Å²	70	46%	0.463	39%	0.393	S	S	.	.	H	α-helix	trans	-62.5	-39.6	179.3	-71.6	-154.8	137	0	0	111.7	R302 S336	R302-E332 IonicContact NH1-OE1 3.97Å; R302-E332 PolarHBondContact NH1-OE1 2.93Å; E332-S336 WeakPolarHBondContact O-CB 3.26Å; E332-S336 PolarHBondContact O-N 3.08Å; E332-S336 PolarHBondContact O-OG 3.24Å
333	D	70.9	Confident	67.5	Low	96 Å²	96	67.2 Å²	67.2	51%	0.513	38%	0.379	S	S	.	.	H	α-helix	trans	-67	-46.9	177.6	-72.5	-18.8	0	0	0	111.3	Q295 E331 S336 E337	Q295-D333 PolarHBondContact NE2-OD1 2.91Å; E331-D333 VanDerWaalsContact C-N 3.32Å; E331-D333 PolarHBondContact O-N 2.95Å; D333-S336 CarbonylContact O-C 3.59Å; D333-S336 PolarHBondContact O-N 2.85Å; D333-E337 WeakPolarHBondContact O-CB 3.34Å; D333-E337 PolarHBondContact O-N 3.08Å
334	I	71.2	Confident	69.3	Low	84 Å²	84	64.5 Å²	64.5	43%	0.431	36%	0.362	S	S	.	.	H	α-helix	trans	-63.1	-48.5	178.5	-62.4	173.2	0	0	0	110.6	E331 S336 E337 I338	E331-I334 PolarHBondContact O-N 2.69Å; I334-S336 PolarHBondContact O-N 3.17Å; I334-E337 PolarHBondContact O-N 3.31Å; I334-I338 HydrophobicContact CG2-CD1 3.68Å; I334-I338 VanDerWaalsContact O-CD1 3.31Å; I334-I338 WeakPolarHBondContact O-CD1 3.45Å; I334-I338 WeakPolarHBondContact O-CG1 3.16Å; I334-I338 PolarHBondContact O-N 2.82Å
335	C	74.9	Confident	70.9	Confident	20 Å²	20	61.1 Å²	61.1	14%	0.135	34%	0.342	C	S	.	.	H	α-helix	trans	-56.9	-41.2	174.4	-72.9	0	0	0	0	111.2	I325 E331 F339	I325-C335 WeakPolarHBondContact CD1-SG 3.27Å; E331-C335 WeakPolarHBondContact O-CB 3.41Å; E331-C335 PolarHBondContact O-N 3.13Å; E331-C335 PolarHBondContact O-SG 2.95Å; C335-F339 WeakPolarHBondContact O-CB 3.46Å; C335-F339 PolarHBondContact O-N 2.83Å
336	S	81.8	Confident	72.9	Confident	4 Å²	4	58.9 Å²	58.9	3%	0.028	33%	0.331	C	S	.	.	H	α-helix	trans	-71.6	-35.7	-179	-62.5	0	0	0	0	112.1	S294 Q295 E332 D333 I334 Y340	S294-S336 WeakPolarHBondContact CB-O 3.4Å; S294-S336 WeakPolarHBondContact OG-CA 3.45Å; S294-S336 PolarHBondContact OG-O 3.04Å; Q295-S336 WeakPolarHBondContact CG-OG 3.4Å; E332-S336 WeakPolarHBondContact O-CB 3.26Å; E332-S336 PolarHBondContact O-N 3.08Å; E332-S336 PolarHBondContact O-OG 3.24Å; D333-S336 CarbonylContact O-C 3.59Å; D333-S336 PolarHBondContact O-N 2.85Å; I334-S336 PolarHBondContact O-N 3.17Å; S336-Y340 VanDerWaalsContact O-CB 3.29Å; S336-Y340 WeakPolarHBondContact O-CB 3.43Å; S336-Y340 PolarHBondContact O-N 3.26Å
337	E	82.3	Confident	74.8	Confident	117 Å²	117	54 Å²	54	55%	0.547	30%	0.297	S	S	.	.	H	α-helix	trans	-64.5	-45.7	173.5	-171	-176.9	162.8	0	0	111.3	I291 D333 I334 Y340 T341	I291-E337 HydrophobicContact CG1-CB 4.38Å; D333-E337 WeakPolarHBondContact O-CB 3.34Å; D333-E337 PolarHBondContact O-N 3.08Å; I334-E337 PolarHBondContact O-N 3.31Å; E337-Y340 WeakPolarHBondContact O-CB 3.37Å; E337-Y340 PolarHBondContact O-N 3.17Å; E337-T341 PolarHBondContact O-N 3.08Å; E337-T341 PolarHBondContact O-OG1 3.46Å
338	I	81.5	Confident	76.9	Confident	20 Å²	20	49.4 Å²	49.4	10%	0.103	27%	0.273	C	S	.	.	H	α-helix	trans	-64.1	-45.8	176.4	-68.2	156.4	0	0	0	110.9	V316 L317 K320 I322 I334 Y340 T341 F342	V316-I338 HydrophobicContact CG1-CG2 3.76Å; L317-I338 HydrophobicContact CD2-CB 4.47Å; L317-I338 HydrophobicContact CD2-CD1 3.69Å; L317-I338 HydrophobicContact CD2-CG2 4.03Å; K320-I338 HydrophobicContact CB-CG2 4.41Å; K320-I338 HydrophobicContact CG-CG2 3.81Å; I322-I338 HydrophobicContact CD1-CD1 3.22Å; I322-I338 HydrophobicContact CD1-CG1 4.05Å; I334-I338 HydrophobicContact CG2-CD1 3.68Å; I334-I338 VanDerWaalsContact O-CD1 3.31Å; I334-I338 WeakPolarHBondContact O-CD1 3.45Å; I334-I338 WeakPolarHBondContact O-CG1 3.16Å; I334-I338 PolarHBondContact O-N 2.82Å; I338-Y340 VanDerWaalsContact C-N 3.27Å; I338-Y340 PolarHBondContact O-N 3.37Å; I338-T341 WeakPolarHBondContact O-CB 3.08Å; I338-T341 PolarHBondContact O-N 2.98Å; I338-T341 VanDerWaalsContact O-N 3.16Å; I338-F342 PolarHBondContact O-N 3.44Å
339	F	88.2	Confident	78.8	Confident	2 Å²	2	43.2 Å²	43.2	1%	0.009	24%	0.241	C	C	.	.	H	α-helix	trans	-64.3	-33.8	176.6	-172.8	-106.1	0	0	0	111.9	S294 V297 L298 V312 V313 V316 C335 T341 F342 I343 I393	S294-F339 WeakPolarHBondContact OG-CD1 3.49Å; V297-F339 HydrophobicContact CB-CE1 4.12Å; V297-F339 HydrophobicContact CG1-CE1 3.74Å; V297-F339 HydrophobicContact CG1-CZ 4.22Å; L298-F339 HydrophobicContact CD1-CB 4.24Å; L298-F339 HydrophobicContact CD1-CD1 3.95Å; L298-F339 HydrophobicContact CD1-CG 4.11Å; L298-F339 HydrophobicContact CD2-CD1 3.68Å; L298-F339 HydrophobicContact CD2-CD2 3.92Å; L298-F339 HydrophobicContact CD2-CE1 3.53Å; L298-F339 HydrophobicContact CD2-CE2 3.77Å; L298-F339 HydrophobicContact CD2-CG 3.86Å; L298-F339 HydrophobicContact CD2-CZ 3.56Å; L298-F339 HydrophobicContact CG-CD1 3.55Å; L298-F339 HydrophobicContact CG-CE1 3.65Å; L298-F339 HydrophobicContact CG-CG 4.05Å; L298-F339 HydrophobicContact CG-CZ 4.22Å; V312-F339 HydrophobicContact CG1-CE2 3.79Å; V313-F339 HydrophobicContact CG2-CD2 4.42Å; V316-F339 HydrophobicContact CG2-CD2 4.39Å; C335-F339 WeakPolarHBondContact O-CB 3.46Å; C335-F339 PolarHBondContact O-N 2.83Å; F339-T341 VanDerWaalsContact C-N 3.29Å; F339-T341 PolarHBondContact O-N 3.33Å; F339-F342 HydrophobicContact CD2-CD1 4.12Å; F339-F342 AromaticContact CE2-CD1 3.83Å; F339-F342 HydrophobicContact CE2-CD1 3.83Å; F339-F342 HydrophobicContact CE2-CE1 4.22Å; F339-F342 HydrophobicContact CZ-CD1 4.43Å; F339-F342 WeakPolarHBondContact O-CB 3.18Å; F339-F342 PolarHBondContact O-N 3.02Å; F339-F342 VanDerWaalsContact O-N 3.09Å; F339-I343 HydrophobicContact CD1-CD1 4.29Å; F339-I343 HydrophobicContact CD1-CG2 4.24Å; F339-I343 HydrophobicContact CE1-CD1 4.23Å; F339-I343 HydrophobicContact CE1-CG2 3.75Å; F339-I343 HydrophobicContact CE2-CG2 4.4Å; F339-I343 HydrophobicContact CZ-CG2 3.86Å; F339-I343 PolarHBondContact O-N 3.47Å; F339-I343 VanDerWaalsContact O-N 3.11Å; F339-I393 HydrophobicContact CE1-CD1 4.44Å; F339-I393 HydrophobicContact CZ-CD1 3.73Å
340	Y	89	Confident	81.1	Confident	9 Å²	9	38.7 Å²	38.7	4%	0.035	20%	0.203	C	C	.	.	H	α-helix	trans	-59.6	-43.6	174	-172.5	-92.5	0	0	0	110.7	K290 F293 S294 S336 E337 I338 F342 I343 E344	K290-Y340 HydrophobicContact CB-CD1 4.01Å; K290-Y340 HydrophobicContact CB-CD2 3.81Å; K290-Y340 HydrophobicContact CB-CE1 3.88Å; K290-Y340 HydrophobicContact CB-CE2 3.65Å; K290-Y340 HydrophobicContact CB-CG 3.97Å; K290-Y340 HydrophobicContact CD-CD1 4.04Å; K290-Y340 HydrophobicContact CD-CE1 3.44Å; K290-Y340 VanDerWaalsContact CD-CE1 3.44Å; K290-Y340 HydrophobicContact CG-CD1 4.36Å; K290-Y340 HydrophobicContact CG-CE1 3.76Å; K290-Y340 HydrophobicContact CG-CE2 3.95Å; K290-Y340 WeakPolarHBondContact O-CD2 3.22Å; F293-Y340 HydrophobicContact CD1-CE2 4.3Å; S294-Y340 PolarHBondContact OG-N 2.76Å; S336-Y340 VanDerWaalsContact O-CB 3.29Å; S336-Y340 WeakPolarHBondContact O-CB 3.43Å; S336-Y340 PolarHBondContact O-N 3.26Å; E337-Y340 WeakPolarHBondContact O-CB 3.37Å; E337-Y340 PolarHBondContact O-N 3.17Å; I338-Y340 VanDerWaalsContact C-N 3.27Å; I338-Y340 PolarHBondContact O-N 3.37Å; Y340-F342 PolarHBondContact O-N 2.93Å; Y340-I343 HydrophobicContact CD2-CD1 4.32Å; Y340-I343 HydrophobicContact CD2-CG1 4.38Å; Y340-I343 WeakPolarHBondContact O-CG1 3.47Å; Y340-I343 PolarHBondContact O-N 2.78Å; Y340-I343 VanDerWaalsContact O-N 3.12Å; Y340-E344 HydrophobicContact CD1-CB 4.16Å; Y340-E344 HydrophobicContact CE1-CB 3.84Å; Y340-E344 HydrophobicContact CE1-CG 3.89Å; Y340-E344 VanDerWaalsContact O-CB 3.29Å; Y340-E344 WeakPolarHBondContact O-CB 3.38Å; Y340-E344 PolarHBondContact O-N 2.74Å
341	T	85.4	Confident	83.3	Confident	55 Å²	55	31.5 Å²	31.5	34%	0.337	17%	0.165	S	C	.	.	H	α-helix	trans	-58.5	-31.5	177.3	-53.2	0	0	0	0	112.3	E337 I338 F339	E337-T341 PolarHBondContact O-N 3.08Å; E337-T341 PolarHBondContact O-OG1 3.46Å; I338-T341 WeakPolarHBondContact O-CB 3.08Å; I338-T341 PolarHBondContact O-N 2.98Å; I338-T341 VanDerWaalsContact O-N 3.16Å; F339-T341 VanDerWaalsContact C-N 3.29Å; F339-T341 PolarHBondContact O-N 3.33Å
342	F	88.5	Confident	84.8	Confident	2 Å²	2	30.7 Å²	30.7	1%	0.009	16%	0.161	C	C	.	.	H	α-helix	trans	-73	-45.1	175.5	164.4	-112.3	0	0	0	112.3	V312 V316 I338 F339 Y340 P345 I393 L431 N432 F435	V312-F342 HydrophobicContact CG1-CE1 4.2Å; V316-F342 HydrophobicContact CG1-CB 3.87Å; V316-F342 HydrophobicContact CG2-CB 3.93Å; V316-F342 HydrophobicContact CG2-CD1 3.86Å; V316-F342 HydrophobicContact CG2-CD2 4.19Å; V316-F342 HydrophobicContact CG2-CE1 4.43Å; V316-F342 HydrophobicContact CG2-CG 3.7Å; I338-F342 PolarHBondContact O-N 3.44Å; F339-F342 HydrophobicContact CD2-CD1 4.12Å; F339-F342 AromaticContact CE2-CD1 3.83Å; F339-F342 HydrophobicContact CE2-CD1 3.83Å; F339-F342 HydrophobicContact CE2-CE1 4.22Å; F339-F342 HydrophobicContact CZ-CD1 4.43Å; F339-F342 WeakPolarHBondContact O-CB 3.18Å; F339-F342 PolarHBondContact O-N 3.02Å; F339-F342 VanDerWaalsContact O-N 3.09Å; Y340-F342 PolarHBondContact O-N 2.93Å; F342-P345 WeakPolarHBondContact O-CD 3.36Å; F342-I393 HydrophobicContact CE1-CD1 4.33Å; F342-L431 HydrophobicContact CD2-CD2 4.08Å; F342-L431 HydrophobicContact CE2-CB 4.28Å; F342-L431 HydrophobicContact CE2-CD2 3.39Å; F342-L431 HydrophobicContact CE2-CG 3.7Å; F342-L431 HydrophobicContact CZ-CD2 3.7Å; F342-L431 HydrophobicContact CZ-CG 4.13Å; F342-N432 PolarHBondContact O-ND2 3.46Å; F342-F435 HydrophobicContact CE1-CE2 4.25Å; F342-F435 HydrophobicContact CE2-CE2 4.46Å; F342-F435 HydrophobicContact CZ-CD2 4.12Å; F342-F435 AromaticContact CZ-CE2 3.52Å; F342-F435 HydrophobicContact CZ-CE2 3.52Å; F342-F435 AromaticContact CZ-CZ 3.85Å; F342-F435 HydrophobicContact CZ-CZ 3.85Å
343	I	91.8	Very high	85.8	Confident	0 Å²	0	27.7 Å²	27.7	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-83.5	-16.9	-177.3	66.4	176.6	0	0	0	113.8	F293 V297 F339 Y340 P345 I346 I347 T389 I393	F293-I343 HydrophobicContact CD1-CD1 4.06Å; F293-I343 HydrophobicContact CE1-CD1 3.98Å; V297-I343 HydrophobicContact CB-CD1 4.39Å; V297-I343 HydrophobicContact CG2-CD1 4.02Å; F339-I343 HydrophobicContact CD1-CD1 4.29Å; F339-I343 HydrophobicContact CD1-CG2 4.24Å; F339-I343 HydrophobicContact CE1-CD1 4.23Å; F339-I343 HydrophobicContact CE1-CG2 3.75Å; F339-I343 HydrophobicContact CE2-CG2 4.4Å; F339-I343 HydrophobicContact CZ-CG2 3.86Å; F339-I343 PolarHBondContact O-N 3.47Å; F339-I343 VanDerWaalsContact O-N 3.11Å; Y340-I343 HydrophobicContact CD2-CD1 4.32Å; Y340-I343 HydrophobicContact CD2-CG1 4.38Å; Y340-I343 WeakPolarHBondContact O-CG1 3.47Å; Y340-I343 PolarHBondContact O-N 2.78Å; Y340-I343 VanDerWaalsContact O-N 3.12Å; I343-P345 VanDerWaalsContact C-CD 3.5Å; I343-I346 WeakPolarHBondContact O-CA 3.25Å; I343-I346 WeakPolarHBondContact O-CB 2.84Å; I343-I346 PolarHBondContact O-N 3.47Å; I343-I347 HydrophobicContact CB-CG1 4.29Å; I343-I347 HydrophobicContact CD1-CG1 4.45Å; I343-I347 HydrophobicContact CG1-CG1 4.32Å; I343-I347 WeakPolarHBondContact O-CG1 3.34Å; I343-I347 PolarHBondContact O-N 3.39Å; I343-T389 HydrophobicContact CG2-CG2 4.48Å; I343-I393 HydrophobicContact CG2-CD1 3.78Å
344	E	89.6	Confident	86.8	Confident	56 Å²	56	23.6 Å²	23.6	26%	0.262	13%	0.126	S	C	.	.	H	α-helix	trans	-52.1	-44.9	-175.9	-179.9	173.6	-137.1	0	0	113.1	K290 Y340 I346 I347 T348	K290-E344 IonicContact NZ-OE1 3.23Å; K290-E344 PolarHBondContact NZ-OE1 3.06Å; Y340-E344 HydrophobicContact CD1-CB 4.16Å; Y340-E344 HydrophobicContact CE1-CB 3.84Å; Y340-E344 HydrophobicContact CE1-CG 3.89Å; Y340-E344 VanDerWaalsContact O-CB 3.29Å; Y340-E344 WeakPolarHBondContact O-CB 3.38Å; Y340-E344 PolarHBondContact O-N 2.74Å; E344-I346 VanDerWaalsContact C-N 3.31Å; E344-I346 PolarHBondContact O-N 3.13Å; E344-I347 PolarHBondContact O-N 2.91Å; E344-T348 HydrophobicContact CG-CG2 3.89Å; E344-T348 WeakPolarHBondContact O-CB 3.26Å; E344-T348 VanDerWaalsContact O-CG2 3.3Å; E344-T348 WeakPolarHBondContact O-CG2 3.28Å; E344-T348 PolarHBondContact O-N 3.01Å; E344-T348 PolarHBondContact O-OG1 3.22Å
345	P	88.2	Confident	87.9	Confident	52 Å²	52	19.6 Å²	19.6	34%	0.338	11%	0.105	S	C	.	.	H	α-helix	trans	-62.9	-33.7	176.1	-23.5	36.1	0	0	0	113.9	F342 I343 S349 Y354	F342-P345 WeakPolarHBondContact O-CD 3.36Å; I343-P345 VanDerWaalsContact C-CD 3.5Å; P345-S349 VanDerWaalsContact O-CB 3.29Å; P345-S349 WeakPolarHBondContact O-CB 3.18Å; P345-S349 PolarHBondContact O-N 3.14Å; P345-S349 PolarHBondContact O-OG 2.91Å; P345-Y354 WeakPolarHBondContact CB-OH 3.44Å
346	I	91.9	Very high	88.8	Confident	0 Å²	0	19.9 Å²	19.9	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-71.7	-40.8	178.3	-58.4	162.1	0	0	0	110.3	I343 E344 S349 V350 F351 Y354 F392 F435	I343-I346 WeakPolarHBondContact O-CA 3.25Å; I343-I346 WeakPolarHBondContact O-CB 2.84Å; I343-I346 PolarHBondContact O-N 3.47Å; E344-I346 VanDerWaalsContact C-N 3.31Å; E344-I346 PolarHBondContact O-N 3.13Å; I346-S349 PolarHBondContact O-OG 2.9Å; I346-V350 PolarHBondContact O-N 3.01Å; I346-F351 HydrophobicContact CG2-CD1 3.56Å; I346-F351 HydrophobicContact CG2-CE1 3.56Å; I346-F351 HydrophobicContact CG2-CG 4.46Å; I346-F351 HydrophobicContact CG2-CZ 4.46Å; I346-F351 PolarHBondContact O-N 3.01Å; I346-Y354 HydrophobicContact CB-CE2 4.26Å; I346-Y354 HydrophobicContact CG1-CD1 4.27Å; I346-Y354 HydrophobicContact CG1-CD2 4.36Å; I346-Y354 HydrophobicContact CG1-CE1 3.74Å; I346-Y354 HydrophobicContact CG1-CE2 3.87Å; I346-F392 HydrophobicContact CD1-CD1 4.21Å; I346-F392 HydrophobicContact CD1-CE1 3.77Å; I346-F392 HydrophobicContact CG1-CE1 4.1Å; I346-F392 HydrophobicContact CG2-CD1 3.92Å; I346-F392 HydrophobicContact CG2-CE1 3.91Å; I346-F435 HydrophobicContact CD1-CD2 4.03Å; I346-F435 HydrophobicContact CD1-CE2 4.44Å
347	I	91.2	Very high	89.3	Confident	1 Å²	1	21.3 Å²	21.3	1%	0.005	11%	0.114	C	C	.	.	H	α-helix	trans	-81.8	-43.9	-173.8	-61.9	-61.5	0	0	0	112.5	F254 I255 F293 I343 E344 S349 V350 T389	F254-I347 HydrophobicContact CD2-CG2 3.84Å; F254-I347 HydrophobicContact CE2-CG2 3.46Å; F254-I347 VanDerWaalsContact CE2-CG2 3.46Å; I255-I347 HydrophobicContact CD1-CG2 4.14Å; I255-I347 HydrophobicContact CG1-CG2 3.99Å; F293-I347 HydrophobicContact CE1-CD1 3.53Å; F293-I347 HydrophobicContact CE1-CG1 3.66Å; F293-I347 HydrophobicContact CE1-CG2 4.14Å; F293-I347 HydrophobicContact CZ-CD1 3.59Å; F293-I347 HydrophobicContact CZ-CG1 4.19Å; F293-I347 HydrophobicContact CZ-CG2 4.33Å; I343-I347 HydrophobicContact CB-CG1 4.29Å; I343-I347 HydrophobicContact CD1-CG1 4.45Å; I343-I347 HydrophobicContact CG1-CG1 4.32Å; I343-I347 WeakPolarHBondContact O-CG1 3.34Å; I343-I347 PolarHBondContact O-N 3.39Å; E344-I347 PolarHBondContact O-N 2.91Å; I347-S349 PolarHBondContact O-N 2.95Å; I347-V350 PolarHBondContact O-N 3.41Å; I347-T389 HydrophobicContact CD1-CG2 3.72Å; I347-T389 WeakPolarHBondContact CD1-OG1 3.22Å; I347-T389 HydrophobicContact CG1-CG2 4.49Å
348	T	86.3	Confident	89.8	Confident	25 Å²	25	18.9 Å²	18.9	15%	0.153	11%	0.11	C	C	.	.	H	α-helix	trans	-63.4	-26.6	176.2	53.5	0	0	0	0	111.8	E344	E344-T348 HydrophobicContact CG-CG2 3.89Å; E344-T348 WeakPolarHBondContact O-CB 3.26Å; E344-T348 VanDerWaalsContact O-CG2 3.3Å; E344-T348 WeakPolarHBondContact O-CG2 3.28Å; E344-T348 PolarHBondContact O-N 3.01Å; E344-T348 PolarHBondContact O-OG1 3.22Å
349	S	84.9	Confident	90.3	Very high	1 Å²	1	18 Å²	18	1%	0.007	11%	0.105	C	C	.	.	T	Hydrogen-bonded Turn	trans	-86.2	-10.5	171	65.3	0	0	0	0	114.1	K213 P345 I346 I347 F351 I352	K213-S349 VanDerWaalsContact NZ-CB 3.29Å; P345-S349 VanDerWaalsContact O-CB 3.29Å; P345-S349 WeakPolarHBondContact O-CB 3.18Å; P345-S349 PolarHBondContact O-N 3.14Å; P345-S349 PolarHBondContact O-OG 2.91Å; I346-S349 PolarHBondContact O-OG 2.9Å; I347-S349 PolarHBondContact O-N 2.95Å; S349-F351 PolarHBondContact O-N 3.27Å; S349-I352 VanDerWaalsContact CB-O 3.24Å; S349-I352 WeakPolarHBondContact CB-O 3.47Å; S349-I352 WeakPolarHBondContact O-CB 3.37Å; S349-I352 WeakPolarHBondContact O-CD1 3.38Å; S349-I352 WeakPolarHBondContact O-CG1 3.5Å; S349-I352 PolarHBondContact O-N 2.74Å; S349-I352 PolarHBondContact OG-O 3.36Å
350	V	90.6	Very high	90.7	Very high	1 Å²	1	17.9 Å²	17.9	1%	0.006	10%	0.104	C	C	.	.	T	Hydrogen-bonded Turn	trans	46.9	48.8	-171	-160.8	0	0	0	0	110.7	I255 I346 I347 I352 W364 L367 L385	I255-V350 HydrophobicContact CD1-CG2 4.07Å; I255-V350 HydrophobicContact CG2-CG2 3.65Å; I346-V350 PolarHBondContact O-N 3.01Å; I347-V350 PolarHBondContact O-N 3.41Å; V350-I352 PolarHBondContact O-N 3.47Å; V350-W364 HydrophobicContact CB-CZ2 3.63Å; V350-W364 HydrophobicContact CG1-CH2 4.4Å; V350-W364 HydrophobicContact CG1-CZ2 3.53Å; V350-W364 HydrophobicContact CG2-CZ2 4.02Å; V350-W364 PolarHBondContact O-NE1 2.97Å; V350-L367 HydrophobicContact CG1-CD1 3.82Å; V350-L385 HydrophobicContact CG1-CD2 4.11Å
351	F	93.5	Very high	90.9	Very high	0 Å²	0	18.1 Å²	18.1	0%	0	11%	0.106	C	C	.	.	T	Hydrogen-bonded Turn	trans	66.3	5.1	-176.8	-49.6	-84.1	0	0	0	116.7	I346 S349 D353 Y354 L355 L360 I363 L385 F388 F392	I346-F351 HydrophobicContact CG2-CD1 3.56Å; I346-F351 HydrophobicContact CG2-CE1 3.56Å; I346-F351 HydrophobicContact CG2-CG 4.46Å; I346-F351 HydrophobicContact CG2-CZ 4.46Å; I346-F351 PolarHBondContact O-N 3.01Å; S349-F351 PolarHBondContact O-N 3.27Å; F351-D353 PolarHBondContact O-N 3.27Å; F351-Y354 PolarHBondContact O-N 3.13Å; F351-L355 HydrophobicContact CB-CD1 3.5Å; F351-L355 VanDerWaalsContact CB-CD1 3.5Å; F351-L355 HydrophobicContact CB-CG 3.96Å; F351-L355 HydrophobicContact CD1-CD1 4.12Å; F351-L355 HydrophobicContact CG-CD1 3.87Å; F351-L355 PolarHBondContact O-N 3.03Å; F351-L360 HydrophobicContact CB-CD1 4.14Å; F351-I363 HydrophobicContact CD2-CD1 4.13Å; F351-I363 HydrophobicContact CD2-CG2 4.22Å; F351-I363 HydrophobicContact CE2-CD1 4.39Å; F351-I363 HydrophobicContact CE2-CG2 4.32Å; F351-I363 HydrophobicContact CG-CD1 4.36Å; F351-L385 HydrophobicContact CE2-CD2 4.5Å; F351-F388 HydrophobicContact CE2-CB 4.11Å; F351-F388 HydrophobicContact CZ-CB 4.03Å; F351-F392 HydrophobicContact CD1-CB 4.32Å; F351-F392 HydrophobicContact CD1-CD1 4.22Å; F351-F392 HydrophobicContact CD1-CD2 4.35Å; F351-F392 HydrophobicContact CD1-CG 4.03Å; F351-F392 HydrophobicContact CE1-CB 3.69Å; F351-F392 AromaticContact CE1-CD1 3.98Å; F351-F392 HydrophobicContact CE1-CD1 3.98Å; F351-F392 AromaticContact CE1-CG 3.8Å; F351-F392 HydrophobicContact CE1-CG 3.8Å
352	I	91.4	Very high	91.4	Very high	0 Å²	0	15.5 Å²	15.5	0%	0	9%	0.09	C	C	.	.	T	Hydrogen-bonded Turn	trans	-68.2	129.6	174.4	-61.6	166.1	0	0	0	108.8	F170 M177 K213 I217 S349 V350 Y354 L360	F170-I352 HydrophobicContact CE2-CG2 4.33Å; F170-I352 HydrophobicContact CZ-CG2 3.75Å; M177-I352 HydrophobicContact CE-CG1 4.33Å; M177-I352 HydrophobicContact CE-CG2 3.86Å; K213-I352 HydrophobicContact CB-CB 4.32Å; K213-I352 HydrophobicContact CB-CD1 3.77Å; K213-I352 HydrophobicContact CB-CG2 4.19Å; K213-I352 HydrophobicContact CD-CB 4.28Å; K213-I352 HydrophobicContact CD-CG2 4.27Å; K213-I352 HydrophobicContact CG-CB 4.37Å; K213-I352 HydrophobicContact CG-CG2 3.98Å; K213-I352 PolarHBondContact NZ-O 3.36Å; K213-I352 WeakPolarHBondContact O-CD1 3.47Å; I217-I352 HydrophobicContact CB-CD1 3.98Å; I217-I352 HydrophobicContact CG2-CD1 4.09Å; S349-I352 VanDerWaalsContact CB-O 3.24Å; S349-I352 WeakPolarHBondContact CB-O 3.47Å; S349-I352 WeakPolarHBondContact O-CB 3.37Å; S349-I352 WeakPolarHBondContact O-CD1 3.38Å; S349-I352 WeakPolarHBondContact O-CG1 3.5Å; S349-I352 PolarHBondContact O-N 2.74Å; S349-I352 PolarHBondContact OG-O 3.36Å; V350-I352 PolarHBondContact O-N 3.47Å; I352-Y354 VanDerWaalsContact C-N 3.33Å; I352-L360 HydrophobicContact CG1-CD1 4.06Å; I352-L360 HydrophobicContact CG1-CD2 4.03Å
353	D	88	Confident	91.7	Very high	37 Å²	37	15.4 Å²	15.4	20%	0.198	9%	0.09	C	C	.	.	T	Hydrogen-bonded Turn	trans	87.8	-27.3	-165.8	-54.7	-36.2	0	0	0	114.7	C174 S176 K213 F351 L436	C174-D353 WeakPolarHBondContact CB-OD1 3.38Å; C174-D353 PolarHBondContact SG-OD1 2.64Å; S176-D353 PolarHBondContact OG-N 2.87Å; K213-D353 WeakPolarHBondContact CE-OD2 3.49Å; K213-D353 IonicContact NZ-OD2 3.92Å; K213-D353 PolarHBondContact NZ-OD2 2.8Å; F351-D353 PolarHBondContact O-N 3.27Å; D353-L436 HydrophobicContact CB-CD2 3.99Å
354	Y	92.5	Very high	91.8	Very high	10 Å²	10	15.4 Å²	15.4	4%	0.039	9%	0.09	C	C	.	.	T	Hydrogen-bonded Turn	trans	-89.4	-25.8	-175.8	-72.4	-87.2	0	0	0	113.7	P345 I346 F351 I352 F392 N432 F435 L436 G439 P440	P345-Y354 WeakPolarHBondContact CB-OH 3.44Å; I346-Y354 HydrophobicContact CB-CE2 4.26Å; I346-Y354 HydrophobicContact CG1-CD1 4.27Å; I346-Y354 HydrophobicContact CG1-CD2 4.36Å; I346-Y354 HydrophobicContact CG1-CE1 3.74Å; I346-Y354 HydrophobicContact CG1-CE2 3.87Å; F351-Y354 PolarHBondContact O-N 3.13Å; I352-Y354 VanDerWaalsContact C-N 3.33Å; Y354-F392 HydrophobicContact CD1-CE1 4.1Å; Y354-F392 AromaticContact CD1-CZ 3.66Å; Y354-F392 HydrophobicContact CD1-CZ 3.66Å; Y354-F392 HydrophobicContact CG-CE1 4.49Å; Y354-F392 HydrophobicContact CG-CZ 4.04Å; Y354-N432 PolarHBondContact OH-OD1 3.4Å; Y354-N432 VanDerWaalsContact OH-OD1 3.12Å; Y354-F435 HydrophobicContact CD1-CB 4.21Å; Y354-F435 HydrophobicContact CE1-CB 4.08Å; Y354-L436 HydrophobicContact CD1-CD2 3.76Å; Y354-L436 HydrophobicContact CD1-CG 4.04Å; Y354-L436 HydrophobicContact CD2-CD2 4.25Å; Y354-L436 HydrophobicContact CE1-CD2 3.8Å; Y354-L436 HydrophobicContact CE1-CG 3.75Å; Y354-L436 HydrophobicContact CE2-CD2 4.25Å; Y354-L436 HydrophobicContact CG-CD2 4.03Å; Y354-G439 CarbonylContact O-C 2.88Å; Y354-G439 WeakPolarHBondContact O-CA 3.27Å; Y354-P440 WeakPolarHBondContact O-CD 3.41Å; Y354-P440 VanDerWaalsContact O-N 3.16Å
355	L	94.4	Very high	92	Very high	0 Å²	0	12.8 Å²	12.8	0%	0	8%	0.077	C	C	.	.	S	Bend	trans	-120.6	154	-173.5	-65.8	175.5	0	0	0	112.6	S176 F351 T359 L360 I363 F392 L442 F447	S176-L355 WeakPolarHBondContact CB-O 3.34Å; S176-L355 PolarHBondContact OG-O 3.12Å; F351-L355 HydrophobicContact CB-CD1 3.5Å; F351-L355 VanDerWaalsContact CB-CD1 3.5Å; F351-L355 HydrophobicContact CB-CG 3.96Å; F351-L355 HydrophobicContact CD1-CD1 4.12Å; F351-L355 HydrophobicContact CG-CD1 3.87Å; F351-L355 PolarHBondContact O-N 3.03Å; L355-T359 HydrophobicContact CD1-CG2 4.08Å; L355-T359 HydrophobicContact CD2-CG2 4.1Å; L355-T359 HydrophobicContact CG-CG2 4.49Å; L355-L360 HydrophobicContact CB-CB 4.26Å; L355-I363 HydrophobicContact CD1-CD1 3.31Å; L355-I363 HydrophobicContact CD1-CG1 4.46Å; L355-F392 HydrophobicContact CD2-CD2 3.84Å; L355-F392 HydrophobicContact CD2-CE2 3.81Å; L355-F392 HydrophobicContact CG-CE2 4.45Å; L355-L442 HydrophobicContact CD2-CB 4.36Å; L355-L442 HydrophobicContact CD2-CD1 4.26Å; L355-F447 HydrophobicContact CD1-CZ 4.39Å; L355-F447 HydrophobicContact CD2-CE2 4.23Å; L355-F447 HydrophobicContact CD2-CZ 4.1Å
356	S	92.8	Very high	92.2	Very high	26 Å²	26	10.4 Å²	10.4	18%	0.182	6%	0.062	C	C	.	.			trans	-61.5	155.9	167.4	67.6	0	0	0	0	111	S358 T359 L360 P440	S356-S358 VanDerWaalsContact C-N 3.27Å; S356-S358 PolarHBondContact O-N 2.86Å; S356-S358 PolarHBondContact OG-OG 3.02Å; S356-T359 PolarHBondContact O-N 3.43Å; S356-T359 PolarHBondContact OG-OG1 3.27Å; S356-T359 VanDerWaalsContact OG-OG1 3.13Å; S356-L360 VanDerWaalsContact O-CB 3.26Å; S356-L360 WeakPolarHBondContact O-CB 3.42Å; S356-L360 PolarHBondContact O-N 3.26Å; S356-P440 WeakPolarHBondContact CB-O 3.35Å
357	Q	93.5	Very high	92.2	Very high	34 Å²	34	10.5 Å²	10.5	16%	0.159	6%	0.063	C	C	.	.	H	α-helix	trans	-55.5	-40.7	-178.1	176.7	171.7	-16.7	0	0	113.2	S179 L220 L361	S179-Q357 PolarHBondContact OG-NE2 3.48Å; S179-Q357 PolarHBondContact OG-OE1 2.8Å; L220-Q357 HydrophobicContact CD1-CG 4.31Å; L220-Q357 HydrophobicContact CD2-CG 4.08Å; Q357-L361 HydrophobicContact CG-CD1 3.96Å; Q357-L361 HydrophobicContact CG-CG 4.42Å; Q357-L361 WeakPolarHBondContact O-CB 3.47Å; Q357-L361 VanDerWaalsContact O-CG 3.28Å; Q357-L361 WeakPolarHBondContact O-CG 3.14Å; Q357-L361 PolarHBondContact O-N 3.3Å
358	S	91.7	Very high	92.1	Very high	66 Å²	66	10.5 Å²	10.5	46%	0.462	6%	0.062	S	C	.	.	H	α-helix	trans	-67.4	-44.4	-178.1	50.4	0	0	0	0	111.8	S356 Y362	S356-S358 VanDerWaalsContact C-N 3.27Å; S356-S358 PolarHBondContact O-N 2.86Å; S356-S358 PolarHBondContact OG-OG 3.02Å; S358-Y362 PolarHBondContact O-N 2.98Å; S358-Y362 VanDerWaalsContact O-N 3.11Å
359	T	93.8	Very high	92.2	Very high	0 Å²	0	9.3 Å²	9.3	0%	0	6%	0.055	C	C	.	.	H	α-helix	trans	-68.9	-42.6	177.6	-53.9	0	0	0	0	111	L355 S356 Y362 I363 L442 K444 F447	L355-T359 HydrophobicContact CD1-CG2 4.08Å; L355-T359 HydrophobicContact CD2-CG2 4.1Å; L355-T359 HydrophobicContact CG-CG2 4.49Å; S356-T359 PolarHBondContact O-N 3.43Å; S356-T359 PolarHBondContact OG-OG1 3.27Å; S356-T359 VanDerWaalsContact OG-OG1 3.13Å; T359-Y362 WeakPolarHBondContact O-CB 3.03Å; T359-Y362 PolarHBondContact O-N 3.38Å; T359-I363 PolarHBondContact O-N 3.09Å; T359-L442 PolarHBondContact OG1-O 3.35Å; T359-K444 HydrophobicContact CG2-CB 4.42Å; T359-K444 PolarHBondContact OG1-N 3.38Å; T359-K444 VanDerWaalsContact OG1-N 3.07Å; T359-F447 HydrophobicContact CG2-CD2 3.63Å; T359-F447 HydrophobicContact CG2-CE2 3.52Å; T359-F447 HydrophobicContact CG2-CZ 4.32Å
360	L	95.1	Very high	92.3	Very high	0 Å²	0	9.4 Å²	9.4	0%	0	6%	0.056	C	C	.	.	H	α-helix	trans	-58.7	-50.7	175.5	-178	67.1	0	0	0	111.6	M177 I217 L220 F351 I352 L355 S356 Y362 I363 W364	M177-L360 HydrophobicContact CE-CD2 3.97Å; I217-L360 HydrophobicContact CD1-CD2 4.01Å; I217-L360 HydrophobicContact CD1-CG 4.1Å; L220-L360 HydrophobicContact CD2-CD2 4.42Å; F351-L360 HydrophobicContact CB-CD1 4.14Å; I352-L360 HydrophobicContact CG1-CD1 4.06Å; I352-L360 HydrophobicContact CG1-CD2 4.03Å; L355-L360 HydrophobicContact CB-CB 4.26Å; S356-L360 VanDerWaalsContact O-CB 3.26Å; S356-L360 WeakPolarHBondContact O-CB 3.42Å; S356-L360 PolarHBondContact O-N 3.26Å; L360-Y362 VanDerWaalsContact C-N 3.26Å; L360-Y362 PolarHBondContact O-N 3.46Å; L360-I363 PolarHBondContact O-N 2.77Å; L360-W364 VanDerWaalsContact O-CD1 3.31Å; L360-W364 PolarHBondContact O-N 3.12Å
361	L	94.5	Very high	92	Very high	14 Å²	14	9.7 Å²	9.7	7%	0.073	6%	0.057	C	C	.	.	H	α-helix	trans	-62.8	-33.4	178.3	-73.9	174.5	0	0	0	112.3	W133 I217 L220 Q357 D365	W133-L361 HydrophobicContact CH2-CD2 4.32Å; I217-L361 HydrophobicContact CD1-CD2 3.98Å; L220-L361 HydrophobicContact CD2-CD2 4.16Å; L220-L361 HydrophobicContact CD2-CG 4.34Å; L220-L361 HydrophobicContact CG-CD2 4.32Å; Q357-L361 HydrophobicContact CG-CD1 3.96Å; Q357-L361 HydrophobicContact CG-CG 4.42Å; Q357-L361 WeakPolarHBondContact O-CB 3.47Å; Q357-L361 VanDerWaalsContact O-CG 3.28Å; Q357-L361 WeakPolarHBondContact O-CG 3.14Å; Q357-L361 PolarHBondContact O-N 3.3Å; L361-D365 WeakPolarHBondContact O-CB 3.41Å; L361-D365 PolarHBondContact O-N 2.97Å
362	Y	94.5	Very high	91.2	Very high	0 Å²	0	10 Å²	10	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-64.3	-47.1	174.1	160.2	-97.6	0	0	0	112	N120 S358 T359 L360 W364 D365 Q366 F388 K444 F447 Q448	N120-Y362 PolarHBondContact OD1-OH 3.19Å; S358-Y362 PolarHBondContact O-N 2.98Å; S358-Y362 VanDerWaalsContact O-N 3.11Å; T359-Y362 WeakPolarHBondContact O-CB 3.03Å; T359-Y362 PolarHBondContact O-N 3.38Å; L360-Y362 VanDerWaalsContact C-N 3.26Å; L360-Y362 PolarHBondContact O-N 3.46Å; Y362-W364 VanDerWaalsContact C-N 3.31Å; Y362-W364 PolarHBondContact O-N 3.11Å; Y362-D365 WeakPolarHBondContact O-CB 3.29Å; Y362-D365 PolarHBondContact O-N 3.26Å; Y362-Q366 HydrophobicContact CE2-CG 4.09Å; Y362-Q366 WeakPolarHBondContact O-CG 3.29Å; Y362-Q366 PolarHBondContact O-N 3.41Å; Y362-F388 AromaticContact CE1-CE1 3.96Å; Y362-F388 HydrophobicContact CE1-CE1 3.96Å; Y362-F388 HydrophobicContact CE1-CZ 4.43Å; Y362-K444 HydrophobicContact CD1-CB 4.14Å; Y362-K444 HydrophobicContact CG-CB 4.09Å; Y362-F447 HydrophobicContact CD1-CB 4.37Å; Y362-F447 HydrophobicContact CE1-CB 3.71Å; Y362-Q448 HydrophobicContact CD2-CG 4.27Å; Y362-Q448 HydrophobicContact CE1-CG 4.24Å; Y362-Q448 HydrophobicContact CE2-CG 3.46Å; Y362-Q448 VanDerWaalsContact CE2-CG 3.46Å; Y362-Q448 VanDerWaalsContact CZ-CG 3.46Å; Y362-Q448 WeakPolarHBondContact OH-CG 3.1Å
363	I	94.7	Very high	90.1	Very high	0 Å²	0	10.3 Å²	10.3	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-59.8	-46.7	176.9	-66.4	-178.3	0	0	0	109.7	F351 L355 T359 L360 D365 Q366 L367 F388 F447	F351-I363 HydrophobicContact CD2-CD1 4.13Å; F351-I363 HydrophobicContact CD2-CG2 4.22Å; F351-I363 HydrophobicContact CE2-CD1 4.39Å; F351-I363 HydrophobicContact CE2-CG2 4.32Å; F351-I363 HydrophobicContact CG-CD1 4.36Å; L355-I363 HydrophobicContact CD1-CD1 3.31Å; L355-I363 HydrophobicContact CD1-CG1 4.46Å; T359-I363 PolarHBondContact O-N 3.09Å; L360-I363 PolarHBondContact O-N 2.77Å; I363-D365 PolarHBondContact O-N 2.84Å; I363-Q366 WeakPolarHBondContact O-CA 3.31Å; I363-Q366 WeakPolarHBondContact O-CB 3.33Å; I363-Q366 PolarHBondContact O-N 3.17Å; I363-L367 HydrophobicContact CG2-CD1 4.34Å; I363-L367 HydrophobicContact CG2-CG 4.43Å; I363-L367 WeakPolarHBondContact O-CG 3.29Å; I363-L367 PolarHBondContact O-N 3.23Å; I363-F388 HydrophobicContact CD1-CD1 4.1Å; I363-F388 HydrophobicContact CD1-CG 4.49Å; I363-F388 HydrophobicContact CG1-CD1 3.88Å; I363-F388 HydrophobicContact CG1-CE1 4.08Å; I363-F388 HydrophobicContact CG1-CG 4.41Å; I363-F388 HydrophobicContact CG2-CB 4.5Å; I363-F388 HydrophobicContact CG2-CD1 4.36Å; I363-F388 HydrophobicContact CG2-CD2 4.11Å; I363-F388 HydrophobicContact CG2-CE2 4.49Å; I363-F388 HydrophobicContact CG2-CG 4.06Å; I363-F447 HydrophobicContact CD1-CD1 4.25Å; I363-F447 HydrophobicContact CD1-CE1 3.87Å; I363-F447 HydrophobicContact CD1-CZ 4.26Å
364	W	94.6	Very high	88.7	Confident	1 Å²	1	10.8 Å²	10.8	0%	0.004	7%	0.071	C	C	.	.	H	α-helix	trans	-65	-34.5	178.6	-84	87.8	0	0	0	113.4	W133 I217 L247 L251 V350 L360 Y362 Q366 L367 M368	W133-W364 HydrophobicContact CH2-CB 3.66Å; W133-W364 HydrophobicContact CH2-CE3 4.36Å; W133-W364 HydrophobicContact CH2-CG 4.31Å; W133-W364 HydrophobicContact CZ2-CB 3.64Å; I217-W364 HydrophobicContact CB-CZ2 4.42Å; I217-W364 HydrophobicContact CD1-CD2 4.44Å; I217-W364 HydrophobicContact CD1-CG 4.05Å; I217-W364 HydrophobicContact CG1-CB 4.48Å; I217-W364 HydrophobicContact CG1-CD2 3.61Å; I217-W364 HydrophobicContact CG1-CE3 4.15Å; I217-W364 HydrophobicContact CG1-CG 3.74Å; I217-W364 HydrophobicContact CG1-CZ2 4.2Å; I217-W364 HydrophobicContact CG2-CD2 4.43Å; I217-W364 HydrophobicContact CG2-CH2 3.78Å; I217-W364 HydrophobicContact CG2-CZ2 3.68Å; I217-W364 HydrophobicContact CG2-CZ3 4.19Å; L247-W364 HydrophobicContact CD1-CZ3 3.89Å; L247-W364 HydrophobicContact CD2-CH2 4.2Å; L247-W364 HydrophobicContact CD2-CZ3 3.9Å; L247-W364 HydrophobicContact CG-CZ3 4.45Å; L251-W364 HydrophobicContact CD1-CH2 4.33Å; L251-W364 HydrophobicContact CD2-CH2 4.31Å; V350-W364 HydrophobicContact CB-CZ2 3.63Å; V350-W364 HydrophobicContact CG1-CH2 4.4Å; V350-W364 HydrophobicContact CG1-CZ2 3.53Å; V350-W364 HydrophobicContact CG2-CZ2 4.02Å; V350-W364 PolarHBondContact O-NE1 2.97Å; L360-W364 VanDerWaalsContact O-CD1 3.31Å; L360-W364 PolarHBondContact O-N 3.12Å; Y362-W364 VanDerWaalsContact C-N 3.31Å; Y362-W364 PolarHBondContact O-N 3.11Å; W364-Q366 VanDerWaalsContact C-N 3.26Å; W364-Q366 PolarHBondContact O-N 3.34Å; W364-L367 HydrophobicContact CD2-CD1 4.16Å; W364-L367 HydrophobicContact CE3-CD1 4.35Å; W364-L367 HydrophobicContact CG-CD1 4.47Å; W364-L367 PolarHBondContact O-N 2.98Å; W364-M368 HydrophobicContact CE3-CE 4.05Å; W364-M368 HydrophobicContact CZ3-CE 4.22Å; W364-M368 VanDerWaalsContact O-CG 3.29Å; W364-M368 WeakPolarHBondContact O-CG 3.01Å; W364-M368 PolarHBondContact O-N 3.32Å
365	D	93.7	Very high	87.3	Confident	0 Å²	0	15.4 Å²	15.4	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-57.8	-40.9	170.1	-71.7	-17	0	0	0	110.4	F123 R129 W133 L361 Y362 I363 M368 L369	F123-D365 HydrophobicContact CD2-CB 3.87Å; F123-D365 WeakPolarHBondContact CD2-OD1 3.47Å; F123-D365 HydrophobicContact CE2-CB 3.89Å; F123-D365 HydrophobicContact CG-CB 4.36Å; F123-D365 HydrophobicContact CZ-CB 4.41Å; F123-D365 PolarHBondContact N-OD2 3Å; R129-D365 WeakPolarHBondContact CD-OD1 3.26Å; R129-D365 IonicContact CZ-OD1 3.32Å; R129-D365 IonicContact CZ-OD2 2.8Å; R129-D365 IonicContact NE-OD1 3.7Å; R129-D365 PolarHBondContact NE-OD1 3.45Å; R129-D365 IonicContact NE-OD2 3.9Å; R129-D365 PolarHBondContact NE-OD2 3.23Å; R129-D365 IonicContact NH2-OD1 3.36Å; R129-D365 IonicContact NH2-OD2 2.88Å; R129-D365 PolarHBondContact NH2-OD2 3.05Å; W133-D365 PolarHBondContact NE1-OD1 3.36Å; L361-D365 WeakPolarHBondContact O-CB 3.41Å; L361-D365 PolarHBondContact O-N 2.97Å; Y362-D365 WeakPolarHBondContact O-CB 3.29Å; Y362-D365 PolarHBondContact O-N 3.26Å; I363-D365 PolarHBondContact O-N 2.84Å; D365-M368 PolarHBondContact O-N 3.07Å; D365-L369 WeakPolarHBondContact O-CG 3.33Å; D365-L369 PolarHBondContact O-N 3.43Å; D365-L369 VanDerWaalsContact O-N 3.09Å
366	Q	91.9	Very high	85.7	Confident	2 Å²	2	17.6 Å²	17.6	1%	0.009	11%	0.107	C	C	.	.	H	α-helix	trans	-70.3	-37.1	177	-53.8	-43.3	-67.8	0	0	112.8	Q121 Y362 I363 W364 M368 L369 C370 F388	Q121-Q366 PolarHBondContact O-NE2 2.8Å; Y362-Q366 HydrophobicContact CE2-CG 4.09Å; Y362-Q366 WeakPolarHBondContact O-CG 3.29Å; Y362-Q366 PolarHBondContact O-N 3.41Å; I363-Q366 WeakPolarHBondContact O-CA 3.31Å; I363-Q366 WeakPolarHBondContact O-CB 3.33Å; I363-Q366 PolarHBondContact O-N 3.17Å; W364-Q366 VanDerWaalsContact C-N 3.26Å; W364-Q366 PolarHBondContact O-N 3.34Å; Q366-M368 VanDerWaalsContact C-N 3.34Å; Q366-L369 PolarHBondContact O-N 3.23Å; Q366-C370 PolarHBondContact O-N 3.16Å; Q366-C370 VanDerWaalsContact O-N 3.08Å; Q366-F388 HydrophobicContact CB-CE2 3.84Å; Q366-F388 HydrophobicContact CB-CZ 3.86Å; Q366-F388 HydrophobicContact CG-CE2 4.27Å; Q366-F388 HydrophobicContact CG-CZ 3.75Å
367	L	91.8	Very high	84.6	Confident	3 Å²	3	20.2 Å²	20.2	2%	0.016	12%	0.119	C	C	.	.	H	α-helix	trans	-63	-41.9	173.3	-61	177.3	0	0	0	110.8	V350 I363 W364 L369 C370 I371 L381 I384 L385	V350-L367 HydrophobicContact CG1-CD1 3.82Å; I363-L367 HydrophobicContact CG2-CD1 4.34Å; I363-L367 HydrophobicContact CG2-CG 4.43Å; I363-L367 WeakPolarHBondContact O-CG 3.29Å; I363-L367 PolarHBondContact O-N 3.23Å; W364-L367 HydrophobicContact CD2-CD1 4.16Å; W364-L367 HydrophobicContact CE3-CD1 4.35Å; W364-L367 HydrophobicContact CG-CD1 4.47Å; W364-L367 PolarHBondContact O-N 2.98Å; L367-L369 VanDerWaalsContact C-N 3.32Å; L367-L369 PolarHBondContact O-N 2.88Å; L367-C370 WeakPolarHBondContact O-CA 3.4Å; L367-C370 WeakPolarHBondContact O-CB 3.4Å; L367-C370 PolarHBondContact O-N 2.87Å; L367-I371 WeakPolarHBondContact O-CG1 3.28Å; L367-I371 PolarHBondContact O-N 3.41Å; L367-I371 VanDerWaalsContact O-N 3.14Å; L367-L381 HydrophobicContact CB-CD1 4.21Å; L367-L381 HydrophobicContact CD2-CD1 3.63Å; L367-L381 HydrophobicContact CG-CD1 4.43Å; L367-I384 HydrophobicContact CD2-CG2 4.05Å; L367-L385 HydrophobicContact CD1-CD2 3.9Å; L367-L385 HydrophobicContact CD2-CD2 3.64Å; L367-L385 HydrophobicContact CD2-CG 3.82Å; L367-L385 HydrophobicContact CG-CD2 4.43Å
368	M	90.6	Very high	83.8	Confident	0 Å²	0	21.9 Å²	21.9	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-62	-38.2	175.7	-69.6	-67.6	167	0	0	112.2	W133 I136 L137 L247 W364 D365 Q366 C370 I371	W133-M368 HydrophobicContact CD2-CE 3.96Å; W133-M368 HydrophobicContact CD2-CG 3.85Å; W133-M368 HydrophobicContact CD2-SD 4.3Å; W133-M368 HydrophobicContact CE3-CE 3.73Å; W133-M368 HydrophobicContact CG-CG 3.95Å; W133-M368 HydrophobicContact CG-SD 4.34Å; W133-M368 HydrophobicContact CH2-CE 4.44Å; W133-M368 HydrophobicContact CZ2-CG 4.25Å; W133-M368 HydrophobicContact CZ3-CE 3.98Å; I136-M368 HydrophobicContact CD1-CB 3.96Å; I136-M368 HydrophobicContact CG2-SD 4.23Å; L137-M368 HydrophobicContact CD1-CE 4.12Å; L137-M368 HydrophobicContact CD1-SD 4.34Å; L137-M368 HydrophobicContact CD2-CE 4.28Å; L137-M368 HydrophobicContact CD2-SD 4.01Å; L137-M368 HydrophobicContact CG-CE 4.46Å; L137-M368 HydrophobicContact CG-SD 4.1Å; L247-M368 HydrophobicContact CD1-CE 4.1Å; W364-M368 HydrophobicContact CE3-CE 4.05Å; W364-M368 HydrophobicContact CZ3-CE 4.22Å; W364-M368 VanDerWaalsContact O-CG 3.29Å; W364-M368 WeakPolarHBondContact O-CG 3.01Å; W364-M368 PolarHBondContact O-N 3.32Å; D365-M368 PolarHBondContact O-N 3.07Å; Q366-M368 VanDerWaalsContact C-N 3.34Å; M368-C370 VanDerWaalsContact C-N 3.3Å; M368-C370 PolarHBondContact O-N 3.25Å; M368-I371 WeakPolarHBondContact O-CB 3.45Å; M368-I371 PolarHBondContact O-N 2.81Å; M368-I371 HydrophobicContact SD-CD1 3.96Å
369	L	88.5	Confident	83.2	Confident	0 Å²	0	22.2 Å²	22.2	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-63.5	-35.3	172.6	-67.6	175.7	0	0	0	112.4	L114 S115 F123 D365 Q366 L367 I371 V372 G373	L114-L369 HydrophobicContact CB-CD2 3.8Å; S115-L369 PolarHBondContact OG-O 3.36Å; F123-L369 HydrophobicContact CE1-CD2 4.1Å; F123-L369 HydrophobicContact CE1-CG 4.43Å; F123-L369 HydrophobicContact CZ-CD2 3.8Å; F123-L369 HydrophobicContact CZ-CG 4Å; D365-L369 WeakPolarHBondContact O-CG 3.33Å; D365-L369 PolarHBondContact O-N 3.43Å; D365-L369 VanDerWaalsContact O-N 3.09Å; Q366-L369 PolarHBondContact O-N 3.23Å; L367-L369 VanDerWaalsContact C-N 3.32Å; L367-L369 PolarHBondContact O-N 2.88Å; L369-I371 VanDerWaalsContact C-N 3.3Å; L369-I371 PolarHBondContact O-N 3.41Å; L369-V372 WeakPolarHBondContact O-CG2 3.31Å; L369-V372 PolarHBondContact O-N 3Å; L369-G373 PolarHBondContact O-N 2.78Å; L369-G373 VanDerWaalsContact O-N 3.11Å
370	C	87	Confident	82.8	Confident	4 Å²	4	22.3 Å²	22.3	3%	0.027	13%	0.13	C	C	.	.	H	α-helix	trans	-62.1	-37.9	172.9	-169.6	0	0	0	0	112.8	Q366 L367 M368 V372 G373 L381 I384 L463	Q366-C370 PolarHBondContact O-N 3.16Å; Q366-C370 VanDerWaalsContact O-N 3.08Å; L367-C370 WeakPolarHBondContact O-CA 3.4Å; L367-C370 WeakPolarHBondContact O-CB 3.4Å; L367-C370 PolarHBondContact O-N 2.87Å; M368-C370 VanDerWaalsContact C-N 3.3Å; M368-C370 PolarHBondContact O-N 3.25Å; C370-V372 PolarHBondContact O-N 3.26Å; C370-G373 PolarHBondContact O-N 3.18Å; C370-L381 HydrophobicContact CB-CD1 4.27Å; C370-I384 HydrophobicContact CB-CD1 3.62Å; C370-I384 VanDerWaalsContact SG-CD1 3.56Å; C370-L463 HydrophobicContact CB-CD2 3.93Å
371	I	83.3	Confident	82.4	Confident	6 Å²	6	22.6 Å²	22.6	3%	0.031	13%	0.131	C	C	.	.	H	α-helix	trans	-63.2	-25.7	-179.6	-63.7	177.6	0	0	0	111.8	I136 L137 R140 L247 I250 L367 M368 L369 P376	I136-I371 HydrophobicContact CG2-CB 4.1Å; I136-I371 HydrophobicContact CG2-CG2 3.95Å; L137-I371 HydrophobicContact CD2-CD1 4.35Å; R140-I371 HydrophobicContact CG-CG2 4.24Å; R140-I371 VanDerWaalsContact CZ-O 3.23Å; R140-I371 PolarHBondContact NE-O 3.18Å; R140-I371 PolarHBondContact NH2-O 2.67Å; L247-I371 HydrophobicContact CD1-CD1 4.38Å; I250-I371 HydrophobicContact CD1-CG2 3.7Å; I250-I371 HydrophobicContact CG2-CD1 4.02Å; I250-I371 HydrophobicContact CG2-CG1 3.77Å; I250-I371 HydrophobicContact CG2-CG2 4.26Å; L367-I371 WeakPolarHBondContact O-CG1 3.28Å; L367-I371 PolarHBondContact O-N 3.41Å; L367-I371 VanDerWaalsContact O-N 3.14Å; M368-I371 WeakPolarHBondContact O-CB 3.45Å; M368-I371 PolarHBondContact O-N 2.81Å; M368-I371 HydrophobicContact SD-CD1 3.96Å; L369-I371 VanDerWaalsContact C-N 3.3Å; L369-I371 PolarHBondContact O-N 3.41Å; I371-P376 WeakPolarHBondContact O-CB 3.48Å
372	V	77.1	Confident	82.2	Confident	6 Å²	6	22.9 Å²	22.9	4%	0.036	13%	0.134	C	C	.	.	H	α-helix	trans	-106.9	2.3	176.8	-69.6	0	0	0	0	114.3	L111 N112 L114 I136 L369 C370	L111-V372 HydrophobicContact CB-CB 4.08Å; L111-V372 HydrophobicContact CB-CG1 4Å; L111-V372 HydrophobicContact CD1-CG1 4.37Å; N112-V372 VanDerWaalsContact CA-O 3.27Å; N112-V372 WeakPolarHBondContact CA-O 3.34Å; L114-V372 HydrophobicContact CB-CG2 4.36Å; L114-V372 HydrophobicContact CD1-CG2 4.2Å; I136-V372 HydrophobicContact CB-CG1 4.04Å; I136-V372 HydrophobicContact CD1-CG2 4.35Å; I136-V372 HydrophobicContact CG1-CG1 3.74Å; I136-V372 HydrophobicContact CG1-CG2 4.18Å; I136-V372 HydrophobicContact CG2-CG1 3.76Å; L369-V372 WeakPolarHBondContact O-CG2 3.31Å; L369-V372 PolarHBondContact O-N 3Å; C370-V372 PolarHBondContact O-N 3.26Å
373	G	67.8	Low	82	Confident	7 Å²	7	24.8 Å²	24.8	7%	0.072	14%	0.142	C	C	.	.	S	Bend	trans	-61.5	175	178.8	0	0	0	0	0	113.6	L369 C370 E375 P376 L463	L369-G373 PolarHBondContact O-N 2.78Å; L369-G373 VanDerWaalsContact O-N 3.11Å; C370-G373 PolarHBondContact O-N 3.18Å; G373-E375 VanDerWaalsContact C-N 3.27Å; G373-E375 PolarHBondContact O-N 3.34Å; G373-P376 WeakPolarHBondContact O-CD 3.45Å; G373-L463 CarbonylContact C-O 3.57Å; G373-L463 VanDerWaalsContact CA-O 3.23Å; G373-L463 WeakPolarHBondContact CA-O 3.35Å
374	A	58.9	Low	81.9	Confident	47 Å²	47	24.8 Å²	24.8	39%	0.388	14%	0.142	S	C	.	.	S	Bend	trans	-58.3	-37	-178	0	0	0	0	0	113.5	L463	A374-L463 PolarHBondContact N-O 3.21Å
375	E	63	Low	81.9	Confident	108 Å²	108	24.8 Å²	24.8	51%	0.505	14%	0.142	S	C	.	.	S	Bend	trans	-128.1	84.4	174.8	-69.2	-169.6	169.5	0	0	110.7	G373 I377 S380	G373-E375 VanDerWaalsContact C-N 3.27Å; G373-E375 PolarHBondContact O-N 3.34Å; E375-I377 HydrophobicContact CB-CD1 4.42Å; E375-I377 HydrophobicContact CB-CG1 4.3Å; E375-I377 PolarHBondContact O-N 2.65Å; E375-S380 VanDerWaalsContact O-CB 3.31Å; E375-S380 WeakPolarHBondContact O-CB 3.42Å; E375-S380 PolarHBondContact O-OG 2.79Å
376	P	62	Low	82	Confident	45 Å²	45	24.8 Å²	24.8	29%	0.292	14%	0.142	S	C	.	.			trans	-82.9	65.6	-178.1	35.5	-32.8	0	0	0	109.2	I371 G373	I371-P376 WeakPolarHBondContact O-CB 3.48Å; G373-P376 WeakPolarHBondContact O-CD 3.45Å
377	I	69.3	Low	82.2	Confident	82 Å²	82	24.7 Å²	24.7	42%	0.421	14%	0.141	S	C	.	.			trans	-107.8	154.9	179.3	52.8	176.6	0	0	0	110.1	E375 S379 S380 L381	E375-I377 HydrophobicContact CB-CD1 4.42Å; E375-I377 HydrophobicContact CB-CG1 4.3Å; E375-I377 PolarHBondContact O-N 2.65Å; I377-S379 WeakPolarHBondContact CD1-OG 3.35Å; I377-S379 VanDerWaalsContact CG1-OG 3.25Å; I377-S379 WeakPolarHBondContact CG1-OG 3.45Å; I377-S379 PolarHBondContact O-N 3.46Å; I377-S379 VanDerWaalsContact O-N 3.07Å; I377-S380 VanDerWaalsContact CG1-OG 3.25Å; I377-S380 WeakPolarHBondContact CG1-OG 3.44Å; I377-S380 WeakPolarHBondContact O-CB 3.38Å; I377-S380 PolarHBondContact O-N 3.23Å; I377-L381 PolarHBondContact O-N 2.97Å
378	E	75.9	Confident	82.4	Confident	69 Å²	69	24.7 Å²	24.7	32%	0.322	14%	0.141	S	C	.	.	H	α-helix	trans	-51.5	-34.1	-179.6	-177.5	176.4	-166.5	0	0	112.3	P252 S253 L381 S382	P252-E378 WeakPolarHBondContact CA-OE1 3.29Å; P252-E378 HydrophobicContact CB-CG 3.99Å; P252-E378 HydrophobicContact CG-CG 4.42Å; S253-E378 PolarHBondContact N-OE1 3.35Å; S253-E378 PolarHBondContact OG-OE1 3.48Å; E378-L381 PolarHBondContact O-N 2.88Å; E378-S382 VanDerWaalsContact O-CB 3.28Å; E378-S382 WeakPolarHBondContact O-CB 3.24Å; E378-S382 PolarHBondContact O-N 3.38Å; E378-S382 PolarHBondContact O-OG 3.09Å
379	S	79.6	Confident	82.7	Confident	72 Å²	72	24.7 Å²	24.7	50%	0.503	14%	0.141	S	C	.	.	H	α-helix	trans	-67.5	-36.8	176.9	54.4	0	0	0	0	113.5	I377 S382 Y383	I377-S379 WeakPolarHBondContact CD1-OG 3.35Å; I377-S379 VanDerWaalsContact CG1-OG 3.25Å; I377-S379 WeakPolarHBondContact CG1-OG 3.45Å; I377-S379 PolarHBondContact O-N 3.46Å; I377-S379 VanDerWaalsContact O-N 3.07Å; S379-S382 PolarHBondContact O-N 3.03Å; S379-Y383 WeakPolarHBondContact O-CB 3.2Å; S379-Y383 PolarHBondContact O-N 3.19Å
380	S	84.1	Confident	83	Confident	3 Å²	3	24.7 Å²	24.7	2%	0.021	14%	0.141	C	C	.	.	H	α-helix	trans	-65.5	-44.5	176.9	-55.3	0	0	0	0	110.7	E375 I377 Y383 I384	E375-S380 VanDerWaalsContact O-CB 3.31Å; E375-S380 WeakPolarHBondContact O-CB 3.42Å; E375-S380 PolarHBondContact O-OG 2.79Å; I377-S380 VanDerWaalsContact CG1-OG 3.25Å; I377-S380 WeakPolarHBondContact CG1-OG 3.44Å; I377-S380 WeakPolarHBondContact O-CB 3.38Å; I377-S380 PolarHBondContact O-N 3.23Å; S380-Y383 PolarHBondContact O-N 3.26Å; S380-I384 PolarHBondContact O-N 2.99Å
381	L	88.5	Confident	83.4	Confident	5 Å²	5	24.5 Å²	24.5	3%	0.026	14%	0.14	C	C	.	.	H	α-helix	trans	-66.3	-41.6	177.3	-171	58.4	0	0	0	111.2	I250 L251 P252 L367 C370 I377 E378 Y383 I384 L385	I250-L381 HydrophobicContact CG2-CD2 4.37Å; I250-L381 WeakPolarHBondContact O-CD2 3.42Å; L251-L381 HydrophobicContact CD2-CD2 4.31Å; P252-L381 HydrophobicContact CG-CD2 4.19Å; P252-L381 HydrophobicContact CG-CG 4.22Å; L367-L381 HydrophobicContact CB-CD1 4.21Å; L367-L381 HydrophobicContact CD2-CD1 3.63Å; L367-L381 HydrophobicContact CG-CD1 4.43Å; C370-L381 HydrophobicContact CB-CD1 4.27Å; I377-L381 PolarHBondContact O-N 2.97Å; E378-L381 PolarHBondContact O-N 2.88Å; L381-Y383 VanDerWaalsContact C-N 3.33Å; L381-Y383 PolarHBondContact O-N 2.93Å; L381-I384 PolarHBondContact O-N 2.8Å; L381-L385 HydrophobicContact CG-CD1 4.17Å; L381-L385 VanDerWaalsContact O-CB 3.31Å; L381-L385 WeakPolarHBondContact O-CB 3.48Å; L381-L385 VanDerWaalsContact O-CG 3.28Å; L381-L385 WeakPolarHBondContact O-CG 3.33Å; L381-L385 PolarHBondContact O-N 3.26Å
382	S	89.8	Confident	84.1	Confident	21 Å²	21	24.2 Å²	24.2	15%	0.147	14%	0.138	C	C	.	.	H	α-helix	trans	-61.4	-40.4	174.2	-61.9	0	0	0	0	112.1	F293 E378 S379 S386	F293-S382 WeakPolarHBondContact CE2-O 3.36Å; E378-S382 VanDerWaalsContact O-CB 3.28Å; E378-S382 WeakPolarHBondContact O-CB 3.24Å; E378-S382 PolarHBondContact O-N 3.38Å; E378-S382 PolarHBondContact O-OG 3.09Å; S379-S382 PolarHBondContact O-N 3.03Å; S382-S386 WeakPolarHBondContact O-CB 3.08Å; S382-S386 PolarHBondContact O-N 2.6Å
383	Y	91.1	Very high	84.9	Confident	39 Å²	39	23.9 Å²	23.9	15%	0.153	14%	0.137	C	C	.	.	H	α-helix	trans	-62.8	-52.1	176.3	176.9	-94.2	0	0	0	111.2	Q300 S379 S380 L381 L385 S386 C387 D458 I459 L462	Q300-Y383 VanDerWaalsContact NE2-CE2 3.3Å; S379-Y383 WeakPolarHBondContact O-CB 3.2Å; S379-Y383 PolarHBondContact O-N 3.19Å; S380-Y383 PolarHBondContact O-N 3.26Å; L381-Y383 VanDerWaalsContact C-N 3.33Å; L381-Y383 PolarHBondContact O-N 2.93Å; Y383-L385 VanDerWaalsContact C-N 3.34Å; Y383-L385 PolarHBondContact O-N 3.32Å; Y383-S386 WeakPolarHBondContact O-CA 3.32Å; Y383-S386 WeakPolarHBondContact O-CB 3.49Å; Y383-S386 PolarHBondContact O-N 3.17Å; Y383-S386 PolarHBondContact O-OG 3.47Å; Y383-C387 PolarHBondContact O-N 3.47Å; Y383-C387 PolarHBondContact O-SG 2.94Å; Y383-D458 HydrophobicContact CE1-CB 4.36Å; Y383-D458 WeakPolarHBondContact OH-CB 3.11Å; Y383-D458 PolarHBondContact OH-OD2 3.29Å; Y383-I459 HydrophobicContact CE1-CG1 3.93Å; Y383-L462 HydrophobicContact CD1-CD2 3.73Å; Y383-L462 HydrophobicContact CE1-CD2 4.48Å; Y383-L462 HydrophobicContact CG-CD2 4.44Å
384	I	91.9	Very high	86.1	Confident	1 Å²	1	25 Å²	25	1%	0.005	14%	0.139	C	C	.	.	H	α-helix	trans	-61.2	-43.5	179.8	-68.9	177.9	0	0	0	111.3	L367 C370 S380 L381 S386 C387 F388 I459 L462 L463	L367-I384 HydrophobicContact CD2-CG2 4.05Å; C370-I384 HydrophobicContact CB-CD1 3.62Å; C370-I384 VanDerWaalsContact SG-CD1 3.56Å; S380-I384 PolarHBondContact O-N 2.99Å; L381-I384 PolarHBondContact O-N 2.8Å; I384-S386 VanDerWaalsContact C-N 3.28Å; I384-S386 PolarHBondContact O-N 2.89Å; I384-C387 WeakPolarHBondContact O-CB 3.24Å; I384-C387 PolarHBondContact O-N 3.19Å; I384-F388 HydrophobicContact CG2-CD2 3.64Å; I384-F388 HydrophobicContact CG2-CE2 3.49Å; I384-F388 VanDerWaalsContact CG2-CE2 3.49Å; I384-F388 VanDerWaalsContact O-CD2 3.29Å; I384-F388 WeakPolarHBondContact O-CD2 3.25Å; I384-F388 PolarHBondContact O-N 3.1Å; I384-I459 HydrophobicContact CD1-CG2 3.94Å; I384-I459 HydrophobicContact CG1-CG1 4.44Å; I384-I459 HydrophobicContact CG1-CG2 4.05Å; I384-L462 HydrophobicContact CD1-CD2 4.07Å; I384-L462 HydrophobicContact CG1-CD2 3.9Å; I384-L463 HydrophobicContact CD1-CD2 3.83Å; I384-L463 HydrophobicContact CD1-CG 4.34Å
385	L	94.1	Very high	87.7	Confident	1 Å²	1	23 Å²	23	1%	0.005	12%	0.123	C	C	.	.	H	α-helix	trans	-59.5	-39.8	173.6	-76.9	169.6	0	0	0	111.6	P252 I255 F293 V350 F351 L367 L381 Y383 C387 F388 T389	P252-L385 HydrophobicContact CG-CD1 3.99Å; I255-L385 HydrophobicContact CD1-CD1 3.65Å; F293-L385 HydrophobicContact CE2-CB 3.93Å; F293-L385 HydrophobicContact CZ-CB 4.13Å; V350-L385 HydrophobicContact CG1-CD2 4.11Å; F351-L385 HydrophobicContact CE2-CD2 4.5Å; L367-L385 HydrophobicContact CD1-CD2 3.9Å; L367-L385 HydrophobicContact CD2-CD2 3.64Å; L367-L385 HydrophobicContact CD2-CG 3.82Å; L367-L385 HydrophobicContact CG-CD2 4.43Å; L381-L385 HydrophobicContact CG-CD1 4.17Å; L381-L385 VanDerWaalsContact O-CB 3.31Å; L381-L385 WeakPolarHBondContact O-CB 3.48Å; L381-L385 VanDerWaalsContact O-CG 3.28Å; L381-L385 WeakPolarHBondContact O-CG 3.33Å; L381-L385 PolarHBondContact O-N 3.26Å; Y383-L385 VanDerWaalsContact C-N 3.34Å; Y383-L385 PolarHBondContact O-N 3.32Å; L385-C387 VanDerWaalsContact C-N 3.34Å; L385-C387 PolarHBondContact O-N 3.39Å; L385-F388 PolarHBondContact O-N 2.82Å; L385-T389 WeakPolarHBondContact O-CB 3.35Å; L385-T389 PolarHBondContact O-N 2.61Å; L385-T389 PolarHBondContact O-OG1 2.85Å
386	S	95.2	Very high	89	Confident	0 Å²	0	17.9 Å²	17.9	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-64.4	-37.5	177.3	78.2	0	0	0	0	112.6	S296 S382 Y383 I384 T389 A390	S296-S386 WeakPolarHBondContact OG-CB 3.33Å; S296-S386 PolarHBondContact OG-OG 2.86Å; S382-S386 WeakPolarHBondContact O-CB 3.08Å; S382-S386 PolarHBondContact O-N 2.6Å; Y383-S386 WeakPolarHBondContact O-CA 3.32Å; Y383-S386 WeakPolarHBondContact O-CB 3.49Å; Y383-S386 PolarHBondContact O-N 3.17Å; Y383-S386 PolarHBondContact O-OG 3.47Å; I384-S386 VanDerWaalsContact C-N 3.28Å; I384-S386 PolarHBondContact O-N 2.89Å; S386-T389 PolarHBondContact O-N 3.02Å; S386-A390 WeakPolarHBondContact O-CB 3.37Å; S386-A390 PolarHBondContact O-N 3.31Å
387	C	95.9	Very high	90.3	Very high	0 Å²	0	18.1 Å²	18.1	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-63.6	-49.4	173	-63.5	0	0	0	0	111.6	Y383 I384 L385 T389 A390 I391 F455 I459	Y383-C387 PolarHBondContact O-N 3.47Å; Y383-C387 PolarHBondContact O-SG 2.94Å; I384-C387 WeakPolarHBondContact O-CB 3.24Å; I384-C387 PolarHBondContact O-N 3.19Å; L385-C387 VanDerWaalsContact C-N 3.34Å; L385-C387 PolarHBondContact O-N 3.39Å; C387-T389 VanDerWaalsContact C-N 3.29Å; C387-T389 PolarHBondContact O-N 3.4Å; C387-A390 PolarHBondContact O-N 3.47Å; C387-I391 WeakPolarHBondContact O-CG1 3.38Å; C387-I391 PolarHBondContact O-N 3.39Å; C387-F455 HydrophobicContact CB-CD2 4.31Å; C387-F455 HydrophobicContact CB-CG 4.28Å; C387-I459 HydrophobicContact CB-CD1 4.22Å
388	F	96.6	Very high	91.1	Very high	2 Å²	2	18.4 Å²	18.4	1%	0.009	10%	0.095	C	C	.	.	H	α-helix	trans	-62.7	-36.5	178.3	-80.3	-63.1	0	0	0	112.7	F351 Y362 I363 Q366 I384 L385 I391 F392 F447 I451	F351-F388 HydrophobicContact CE2-CB 4.11Å; F351-F388 HydrophobicContact CZ-CB 4.03Å; Y362-F388 AromaticContact CE1-CE1 3.96Å; Y362-F388 HydrophobicContact CE1-CE1 3.96Å; Y362-F388 HydrophobicContact CE1-CZ 4.43Å; I363-F388 HydrophobicContact CD1-CD1 4.1Å; I363-F388 HydrophobicContact CD1-CG 4.49Å; I363-F388 HydrophobicContact CG1-CD1 3.88Å; I363-F388 HydrophobicContact CG1-CE1 4.08Å; I363-F388 HydrophobicContact CG1-CG 4.41Å; I363-F388 HydrophobicContact CG2-CB 4.5Å; I363-F388 HydrophobicContact CG2-CD1 4.36Å; I363-F388 HydrophobicContact CG2-CD2 4.11Å; I363-F388 HydrophobicContact CG2-CE2 4.49Å; I363-F388 HydrophobicContact CG2-CG 4.06Å; Q366-F388 HydrophobicContact CB-CE2 3.84Å; Q366-F388 HydrophobicContact CB-CZ 3.86Å; Q366-F388 HydrophobicContact CG-CE2 4.27Å; Q366-F388 HydrophobicContact CG-CZ 3.75Å; I384-F388 HydrophobicContact CG2-CD2 3.64Å; I384-F388 HydrophobicContact CG2-CE2 3.49Å; I384-F388 VanDerWaalsContact CG2-CE2 3.49Å; I384-F388 VanDerWaalsContact O-CD2 3.29Å; I384-F388 WeakPolarHBondContact O-CD2 3.25Å; I384-F388 PolarHBondContact O-N 3.1Å; L385-F388 PolarHBondContact O-N 2.82Å; F388-I391 PolarHBondContact O-N 2.89Å; F388-F392 VanDerWaalsContact O-CB 3.31Å; F388-F392 WeakPolarHBondContact O-CB 3.41Å; F388-F392 PolarHBondContact O-N 3.42Å; F388-F447 AromaticContact CD1-CD1 3.83Å; F388-F447 HydrophobicContact CD1-CD1 3.83Å; F388-F447 HydrophobicContact CD1-CE1 4.33Å; F388-F447 HydrophobicContact CE1-CD1 4.27Å; F388-I451 HydrophobicContact CE1-CD1 3.97Å; F388-I451 HydrophobicContact CE1-CG1 4.04Å; F388-I451 HydrophobicContact CZ-CD1 4.05Å; F388-I451 HydrophobicContact CZ-CG1 4.32Å
389	T	96.7	Very high	91.5	Very high	0 Å²	0	19.3 Å²	19.3	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-67.8	-44.4	177.7	-52.8	0	0	0	0	111	V297 I343 I347 L385 S386 C387 I391 F392 I393	V297-T389 HydrophobicContact CG1-CG2 3.8Å; V297-T389 HydrophobicContact CG2-CG2 4.07Å; I343-T389 HydrophobicContact CG2-CG2 4.48Å; I347-T389 HydrophobicContact CD1-CG2 3.72Å; I347-T389 WeakPolarHBondContact CD1-OG1 3.22Å; I347-T389 HydrophobicContact CG1-CG2 4.49Å; L385-T389 WeakPolarHBondContact O-CB 3.35Å; L385-T389 PolarHBondContact O-N 2.61Å; L385-T389 PolarHBondContact O-OG1 2.85Å; S386-T389 PolarHBondContact O-N 3.02Å; C387-T389 VanDerWaalsContact C-N 3.29Å; C387-T389 PolarHBondContact O-N 3.4Å; T389-I391 VanDerWaalsContact C-N 3.35Å; T389-I391 PolarHBondContact O-N 3.41Å; T389-F392 PolarHBondContact O-N 2.91Å; T389-I393 HydrophobicContact CG2-CD1 3.96Å; T389-I393 HydrophobicContact CG2-CG1 4.48Å; T389-I393 VanDerWaalsContact O-CG1 3.24Å; T389-I393 WeakPolarHBondContact O-CG1 3.29Å; T389-I393 PolarHBondContact O-N 3.04Å
390	A	96.2	Very high	91.5	Very high	0 Å²	0	17.7 Å²	17.7	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-61.5	-43.5	175.4	0	0	0	0	0	111.9	V297 Q300 L301 I304 S386 C387 I393 F394	V297-A390 HydrophobicContact CG1-CB 4.49Å; Q300-A390 HydrophobicContact CB-CB 3.62Å; L301-A390 HydrophobicContact CB-CB 4.06Å; L301-A390 WeakPolarHBondContact CD1-O 3.19Å; I304-A390 HydrophobicContact CD1-CB 4.08Å; S386-A390 WeakPolarHBondContact O-CB 3.37Å; S386-A390 PolarHBondContact O-N 3.31Å; C387-A390 PolarHBondContact O-N 3.47Å; A390-I393 PolarHBondContact O-N 3.08Å; A390-F394 WeakPolarHBondContact O-CB 3.36Å; A390-F394 PolarHBondContact O-N 3.16Å
391	I	95.5	Very high	90.3	Very high	0 Å²	0	22.3 Å²	22.3	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-60.1	-47.2	174.5	-71.3	169.7	0	0	0	111	I304 C387 F388 T389 I393 F394 L395 F447 L450 I451 F455	I304-I391 HydrophobicContact CD1-CG1 3.96Å; C387-I391 WeakPolarHBondContact O-CG1 3.38Å; C387-I391 PolarHBondContact O-N 3.39Å; F388-I391 PolarHBondContact O-N 2.89Å; T389-I391 VanDerWaalsContact C-N 3.35Å; T389-I391 PolarHBondContact O-N 3.41Å; I391-I393 PolarHBondContact O-N 3.3Å; I391-F394 PolarHBondContact O-N 3.11Å; I391-L395 HydrophobicContact CG2-CD1 3.65Å; I391-L395 HydrophobicContact CG2-CG 4.18Å; I391-L395 WeakPolarHBondContact O-CB 3.09Å; I391-L395 WeakPolarHBondContact O-CG 3.38Å; I391-L395 PolarHBondContact O-N 2.92Å; I391-F447 HydrophobicContact CB-CD1 4.17Å; I391-F447 HydrophobicContact CB-CE1 4.24Å; I391-F447 HydrophobicContact CG2-CD1 3.35Å; I391-F447 HydrophobicContact CG2-CE1 3.59Å; I391-F447 HydrophobicContact CG2-CG 3.98Å; I391-F447 HydrophobicContact CG2-CZ 4.37Å; I391-L450 HydrophobicContact CB-CD1 4.48Å; I391-L450 HydrophobicContact CD1-CB 3.96Å; I391-L450 HydrophobicContact CG1-CB 4Å; I391-L450 HydrophobicContact CG1-CD1 4.44Å; I391-L450 HydrophobicContact CG2-CB 4.18Å; I391-L450 HydrophobicContact CG2-CD1 3.64Å; I391-I451 HydrophobicContact CD1-CD1 3.51Å; I391-I451 HydrophobicContact CD1-CG1 3.75Å; I391-F455 HydrophobicContact CD1-CD2 3.93Å; I391-F455 HydrophobicContact CD1-CE2 3.93Å; I391-F455 HydrophobicContact CG1-CD2 4.41Å; I391-F455 HydrophobicContact CG1-CE2 3.89Å
392	F	96.9	Very high	88.5	Confident	0 Å²	0	27.8 Å²	27.8	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-59.3	-48.3	179.1	173.7	-107.1	0	0	0	111.9	I346 F351 Y354 L355 F388 T389 F394 L395 C396 F435 L442 F447	I346-F392 HydrophobicContact CD1-CD1 4.21Å; I346-F392 HydrophobicContact CD1-CE1 3.77Å; I346-F392 HydrophobicContact CG1-CE1 4.1Å; I346-F392 HydrophobicContact CG2-CD1 3.92Å; I346-F392 HydrophobicContact CG2-CE1 3.91Å; F351-F392 HydrophobicContact CD1-CB 4.32Å; F351-F392 HydrophobicContact CD1-CD1 4.22Å; F351-F392 HydrophobicContact CD1-CD2 4.35Å; F351-F392 HydrophobicContact CD1-CG 4.03Å; F351-F392 HydrophobicContact CE1-CB 3.69Å; F351-F392 AromaticContact CE1-CD1 3.98Å; F351-F392 HydrophobicContact CE1-CD1 3.98Å; F351-F392 AromaticContact CE1-CG 3.8Å; F351-F392 HydrophobicContact CE1-CG 3.8Å; Y354-F392 HydrophobicContact CD1-CE1 4.1Å; Y354-F392 AromaticContact CD1-CZ 3.66Å; Y354-F392 HydrophobicContact CD1-CZ 3.66Å; Y354-F392 HydrophobicContact CG-CE1 4.49Å; Y354-F392 HydrophobicContact CG-CZ 4.04Å; L355-F392 HydrophobicContact CD2-CD2 3.84Å; L355-F392 HydrophobicContact CD2-CE2 3.81Å; L355-F392 HydrophobicContact CG-CE2 4.45Å; F388-F392 VanDerWaalsContact O-CB 3.31Å; F388-F392 WeakPolarHBondContact O-CB 3.41Å; F388-F392 PolarHBondContact O-N 3.42Å; T389-F392 PolarHBondContact O-N 2.91Å; F392-F394 PolarHBondContact O-N 3.34Å; F392-L395 PolarHBondContact O-N 2.99Å; F392-C396 WeakPolarHBondContact CE2-SG 3.23Å; F392-C396 VanDerWaalsContact CZ-SG 3.52Å; F392-C396 WeakPolarHBondContact O-CB 3.36Å; F392-C396 PolarHBondContact O-N 2.78Å; F392-C396 PolarHBondContact O-SG 3.48Å; F392-F435 HydrophobicContact CD1-CD2 4.43Å; F392-F435 HydrophobicContact CE1-CB 4.47Å; F392-F435 AromaticContact CE1-CD2 3.65Å; F392-F435 HydrophobicContact CE1-CD2 3.65Å; F392-F435 HydrophobicContact CE1-CE2 4.29Å; F392-F435 HydrophobicContact CE1-CG 4.44Å; F392-F435 HydrophobicContact CZ-CB 4.26Å; F392-F435 HydrophobicContact CZ-CD2 4.17Å; F392-L442 HydrophobicContact CD2-CD1 3.8Å; F392-L442 HydrophobicContact CE2-CD1 3.99Å; F392-F447 HydrophobicContact CB-CE1 4.24Å; F392-F447 HydrophobicContact CB-CZ 4.2Å; F392-F447 HydrophobicContact CD2-CZ 4.25Å
393	I	94.7	Very high	85.9	Confident	0 Å²	0	35 Å²	35	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-60.1	-47.3	177.3	-66.6	169.6	0	0	0	110.2	V297 L301 V312 F339 F342 I343 T389 A390 I391 C396 W397 F435	V297-I393 HydrophobicContact CG1-CD1 3.95Å; L301-I393 HydrophobicContact CD1-CG2 4.33Å; L301-I393 HydrophobicContact CD2-CG2 3.83Å; V312-I393 HydrophobicContact CG1-CG2 4.15Å; V312-I393 HydrophobicContact CG2-CG2 3.97Å; F339-I393 HydrophobicContact CE1-CD1 4.44Å; F339-I393 HydrophobicContact CZ-CD1 3.73Å; F342-I393 HydrophobicContact CE1-CD1 4.33Å; I343-I393 HydrophobicContact CG2-CD1 3.78Å; T389-I393 HydrophobicContact CG2-CD1 3.96Å; T389-I393 HydrophobicContact CG2-CG1 4.48Å; T389-I393 VanDerWaalsContact O-CG1 3.24Å; T389-I393 WeakPolarHBondContact O-CG1 3.29Å; T389-I393 PolarHBondContact O-N 3.04Å; A390-I393 PolarHBondContact O-N 3.08Å; I391-I393 PolarHBondContact O-N 3.3Å; I393-C396 PolarHBondContact O-N 2.94Å; I393-W397 WeakPolarHBondContact O-CB 3.05Å; I393-W397 PolarHBondContact O-N 3Å; I393-F435 HydrophobicContact CB-CE2 4.44Å; I393-F435 HydrophobicContact CG1-CE2 4.1Å; I393-F435 HydrophobicContact CG2-CE2 4.46Å; I393-F435 HydrophobicContact CG2-CZ 4.35Å
394	F	92.5	Very high	83	Confident	29 Å²	29	37.3 Å²	37.3	13%	0.127	20%	0.2	C	C	.	.	H	α-helix	trans	-57.7	-50.5	177.6	172	-94.9	0	0	0	111.8	L301 I304 D305 I308 A390 I391 F392 C396 W397 I398 L450	L301-F394 HydrophobicContact CD1-CB 3.92Å; I304-F394 HydrophobicContact CG2-CB 4.38Å; I304-F394 HydrophobicContact CG2-CD1 4.14Å; I304-F394 HydrophobicContact CG2-CD2 3.54Å; I304-F394 HydrophobicContact CG2-CE1 4.32Å; I304-F394 HydrophobicContact CG2-CE2 3.73Å; I304-F394 HydrophobicContact CG2-CG 3.76Å; I304-F394 HydrophobicContact CG2-CZ 4.13Å; D305-F394 HydrophobicContact CB-CD2 4.2Å; D305-F394 HydrophobicContact CB-CE2 3.96Å; I308-F394 HydrophobicContact CD1-CD2 3.63Å; I308-F394 HydrophobicContact CD1-CE2 3.49Å; I308-F394 VanDerWaalsContact CD1-CE2 3.49Å; A390-F394 WeakPolarHBondContact O-CB 3.36Å; A390-F394 PolarHBondContact O-N 3.16Å; I391-F394 PolarHBondContact O-N 3.11Å; F392-F394 PolarHBondContact O-N 3.34Å; F394-C396 PolarHBondContact O-N 2.63Å; F394-W397 PolarHBondContact O-N 2.88Å; F394-I398 HydrophobicContact CD2-CG2 4.49Å; F394-I398 HydrophobicContact CE1-CD1 4.14Å; F394-I398 HydrophobicContact CE2-CG2 4.17Å; F394-I398 HydrophobicContact CZ-CG2 4.18Å; F394-I398 WeakPolarHBondContact O-CG1 3.42Å; F394-I398 WeakPolarHBondContact O-CG2 3.32Å; F394-I398 PolarHBondContact O-N 3.21Å; F394-I398 VanDerWaalsContact O-N 3.12Å; F394-L450 HydrophobicContact CD1-CD1 3.8Å; F394-L450 HydrophobicContact CE1-CD1 4.06Å; F394-L450 HydrophobicContact CE1-CD2 4.2Å
395	L	91.9	Very high	80.4	Confident	7 Å²	7	43.6 Å²	43.6	4%	0.037	23%	0.231	C	C	.	.	H	α-helix	trans	-65.7	-36.4	-177.5	-74.3	174.7	0	0	0	113.2	I391 F392 I398 R399 L442 D446 F447 L450	I391-L395 HydrophobicContact CG2-CD1 3.65Å; I391-L395 HydrophobicContact CG2-CG 4.18Å; I391-L395 WeakPolarHBondContact O-CB 3.09Å; I391-L395 WeakPolarHBondContact O-CG 3.38Å; I391-L395 PolarHBondContact O-N 2.92Å; F392-L395 PolarHBondContact O-N 2.99Å; L395-I398 HydrophobicContact CD2-CD1 4.35Å; L395-I398 WeakPolarHBondContact O-CG1 2.94Å; L395-R399 PolarHBondContact O-NH1 3.31Å; L395-L442 HydrophobicContact CB-CD1 3.84Å; L395-L442 HydrophobicContact CB-CD2 3.89Å; L395-L442 HydrophobicContact CD1-CD1 4.37Å; L395-D446 HydrophobicContact CD1-CB 3.83Å; L395-D446 HydrophobicContact CD2-CB 3.99Å; L395-F447 HydrophobicContact CD1-CD2 3.91Å; L395-F447 HydrophobicContact CD1-CE2 3.77Å; L395-F447 HydrophobicContact CD1-CG 4.35Å; L395-F447 HydrophobicContact CD1-CZ 4.11Å; L395-L450 HydrophobicContact CD1-CD1 4.04Å; L395-L450 HydrophobicContact CD2-CD1 3.64Å; L395-L450 HydrophobicContact CG-CD1 3.7Å
396	C	91.5	Very high	77.4	Confident	0 Å²	0	47.1 Å²	47.1	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-68.3	-47.4	173.1	-68.6	0	0	0	0	110.5	F392 I393 F394 I398 R399 I400 F435 I438	F392-C396 WeakPolarHBondContact CE2-SG 3.23Å; F392-C396 VanDerWaalsContact CZ-SG 3.52Å; F392-C396 WeakPolarHBondContact O-CB 3.36Å; F392-C396 PolarHBondContact O-N 2.78Å; F392-C396 PolarHBondContact O-SG 3.48Å; I393-C396 PolarHBondContact O-N 2.94Å; F394-C396 PolarHBondContact O-N 2.63Å; C396-I398 PolarHBondContact O-N 3.16Å; C396-R399 PolarHBondContact O-N 2.83Å; C396-I400 PolarHBondContact O-N 3.48Å; C396-F435 HydrophobicContact CB-CD1 3.63Å; C396-F435 HydrophobicContact CB-CD2 4.17Å; C396-F435 HydrophobicContact CB-CE1 3.55Å; C396-F435 HydrophobicContact CB-CE2 4.08Å; C396-F435 HydrophobicContact CB-CG 3.94Å; C396-F435 HydrophobicContact CB-CZ 3.78Å; C396-I438 HydrophobicContact CB-CG2 4.42Å
397	W	88.6	Confident	74.6	Confident	50 Å²	50	51.8 Å²	51.8	19%	0.189	28%	0.281	C	S	.	.	H	α-helix	trans	-59	-44.8	-175.1	-170.1	-91	0	0	0	113	I308 V312 Q315 I393 F394 R399 I400 L431	I308-W397 HydrophobicContact CG2-CB 4.13Å; I308-W397 HydrophobicContact CG2-CG 3.82Å; V312-W397 HydrophobicContact CB-CE3 4.34Å; V312-W397 HydrophobicContact CB-CZ3 4.22Å; V312-W397 HydrophobicContact CG1-CZ3 4.46Å; V312-W397 HydrophobicContact CG2-CD2 3.52Å; V312-W397 HydrophobicContact CG2-CE3 3.41Å; V312-W397 VanDerWaalsContact CG2-CE3 3.41Å; V312-W397 HydrophobicContact CG2-CG 4.07Å; V312-W397 HydrophobicContact CG2-CH2 4.2Å; V312-W397 HydrophobicContact CG2-CZ2 4.33Å; V312-W397 HydrophobicContact CG2-CZ3 3.76Å; Q315-W397 HydrophobicContact CB-CH2 3.8Å; Q315-W397 HydrophobicContact CB-CZ3 4.31Å; Q315-W397 HydrophobicContact CG-CH2 4.2Å; I393-W397 WeakPolarHBondContact O-CB 3.05Å; I393-W397 PolarHBondContact O-N 3Å; F394-W397 PolarHBondContact O-N 2.88Å; W397-R399 PolarHBondContact O-N 3.43Å; W397-R399 VanDerWaalsContact O-N 3.16Å; W397-I400 HydrophobicContact CD2-CD1 4.42Å; W397-I400 HydrophobicContact CE3-CD1 3.93Å; W397-I400 HydrophobicContact CZ3-CD1 4.39Å; W397-I400 PolarHBondContact O-N 3.06Å; W397-L431 HydrophobicContact CZ3-CD1 4.28Å; W397-L431 HydrophobicContact CZ3-CD2 4.46Å
398	I	86.4	Confident	72	Confident	87 Å²	87	54.9 Å²	54.9	45%	0.446	30%	0.297	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.6	-15.4	179.1	64	172	0	0	0	113.6	I308 F394 L395 C396	I308-I398 HydrophobicContact CD1-CG2 3.68Å; F394-I398 HydrophobicContact CD2-CG2 4.49Å; F394-I398 HydrophobicContact CE1-CD1 4.14Å; F394-I398 HydrophobicContact CE2-CG2 4.17Å; F394-I398 HydrophobicContact CZ-CG2 4.18Å; F394-I398 WeakPolarHBondContact O-CG1 3.42Å; F394-I398 WeakPolarHBondContact O-CG2 3.32Å; F394-I398 PolarHBondContact O-N 3.21Å; F394-I398 VanDerWaalsContact O-N 3.12Å; L395-I398 HydrophobicContact CD2-CD1 4.35Å; L395-I398 WeakPolarHBondContact O-CG1 2.94Å; C396-I398 PolarHBondContact O-N 3.16Å
399	R	84	Confident	69.2	Low	89 Å²	89	61.5 Å²	61.5	34%	0.336	33%	0.332	S	S	.	.	T	Hydrogen-bonded Turn	trans	-101.3	-6	-179.6	-75.4	177	176.3	84.3	-7.4	113.4	L395 C396 W397 P401 I438 D446	L395-R399 PolarHBondContact O-NH1 3.31Å; C396-R399 PolarHBondContact O-N 2.83Å; W397-R399 PolarHBondContact O-N 3.43Å; W397-R399 VanDerWaalsContact O-N 3.16Å; R399-P401 WeakPolarHBondContact O-CD 3.44Å; R399-I438 HydrophobicContact CB-CD1 4.29Å; R399-I438 HydrophobicContact CB-CG2 3.74Å; R399-I438 HydrophobicContact CG-CG2 4.42Å; R399-D446 IonicContact CZ-OD2 2.93Å; R399-D446 IonicContact NH1-OD2 2.88Å; R399-D446 IonicContact NH2-OD2 3.28Å; R399-D446 PolarHBondContact NH2-OD2 3.38Å
400	I	79.4	Confident	66.4	Low	37 Å²	37	68.6 Å²	68.6	19%	0.19	37%	0.365	C	S	.	.	S	Bend	trans	-66.2	122.6	172.5	-63.7	173.4	0	0	0	108	C396 W397 S402 L431 Q434 F435 I438	C396-I400 PolarHBondContact O-N 3.48Å; W397-I400 HydrophobicContact CD2-CD1 4.42Å; W397-I400 HydrophobicContact CE3-CD1 3.93Å; W397-I400 HydrophobicContact CZ3-CD1 4.39Å; W397-I400 PolarHBondContact O-N 3.06Å; I400-S402 PolarHBondContact O-N 3.4Å; I400-L431 HydrophobicContact CD1-CD1 3.93Å; I400-Q434 VanDerWaalsContact CG2-OE1 3.24Å; I400-F435 HydrophobicContact CD1-CE1 4.11Å; I400-I438 HydrophobicContact CG1-CD1 3.76Å
401	P	59.1	Low	63.8	Low	101 Å²	101	73.5 Å²	73.5	66%	0.656	39%	0.385	S	S	*	.			trans	-56.4	126.6	172.2	-20	31.1	0	0	0	108.6	R399 H403	R399-P401 WeakPolarHBondContact O-CD 3.44Å; P401-H403 VanDerWaalsContact C-N 3.28Å; P401-H403 PolarHBondContact O-N 2.91Å
402	S	50.8	Low	61.4	Low	120 Å²	120	81.6 Å²	81.6	84%	0.839	42%	0.422	S	S	*	.			trans	-64.1	89	180	-27.2	0	0	0	0	109.2	I400	I400-S402 PolarHBondContact O-N 3.4Å
403	H	35.6	Very low	58.9	Low	172 Å²	172	89.9 Å²	89.9	80%	0.796	46%	0.461	S	S	*	.			trans	-64.8	124	158.3	-97.6	-54.2	0	0	0	105.7	P401 M405	P401-H403 VanDerWaalsContact C-N 3.28Å; P401-H403 PolarHBondContact O-N 2.91Å; H403-M405 PolarHBondContact O-N 3.45Å
404	P	28.8	Very low	56.7	Low	88 Å²	88	92.2 Å²	92.2	57%	0.571	47%	0.473	S	S	*	.			trans	-57.6	130.1	178.9	25	-31.3	0	0	0	107.3	S406	P404-S406 PolarHBondContact O-N 3.09Å; P404-S406 PolarHBondContact O-OG 3.02Å
405	M	38.2	Very low	54.3	Low	132 Å²	132	97.6 Å²	97.6	65%	0.65	50%	0.503	S	S	*	.	G	3₁₀ helix	trans	-60.9	26	172.7	-77.8	-76.8	-102.2	0	0	113	H403 I408	H403-M405 PolarHBondContact O-N 3.45Å; M405-I408 HydrophobicContact CB-CD1 4.41Å; M405-I408 HydrophobicContact CE-CD1 3.47Å; M405-I408 VanDerWaalsContact CE-CD1 3.47Å; M405-I408 HydrophobicContact SD-CD1 3.49Å; M405-I408 WeakPolarHBondContact SD-CD1 3.44Å; M405-I408 HydrophobicContact SD-CG1 4.43Å
406	S	31.2	Very low	52.2	Low	76 Å²	76	100.1 Å²	100.1	53%	0.531	52%	0.519	S	S	.	.	G	3₁₀ helix	trans	-82.2	-11.8	-176.7	46.5	0	0	0	0	114.4	P404	P404-S406 PolarHBondContact O-N 3.09Å; P404-S406 PolarHBondContact O-OG 3.02Å
407	D	36.5	Very low	50.3	Low	98 Å²	98	106.6 Å²	106.6	52%	0.524	55%	0.552	S	S	.	*	G	3₁₀ helix	trans	-91.5	-2.3	179.7	-75.7	-21.5	0	0	0	114.6	N409 Q410	D407-N409 PolarHBondContact O-N 3.48Å; D407-N409 VanDerWaalsContact O-N 3.16Å; D407-Q410 PolarHBondContact O-N 3.41Å; D407-Q410 VanDerWaalsContact O-N 3.09Å
408	I	41.2	Very low	48.3	Very low	64 Å²	64	108.4 Å²	108.4	33%	0.328	57%	0.572	S	S	.	*	G	3₁₀ helix	trans	-62.1	-25.5	176.4	-66.8	175.4	0	0	0	111.6	F318 M405 Q410	F318-I408 HydrophobicContact CE2-CG1 4.36Å; F318-I408 HydrophobicContact CE2-CG2 4.04Å; F318-I408 HydrophobicContact CZ-CG1 4.24Å; M405-I408 HydrophobicContact CB-CD1 4.41Å; M405-I408 HydrophobicContact CE-CD1 3.47Å; M405-I408 VanDerWaalsContact CE-CD1 3.47Å; M405-I408 HydrophobicContact SD-CD1 3.49Å; M405-I408 WeakPolarHBondContact SD-CD1 3.44Å; M405-I408 HydrophobicContact SD-CG1 4.43Å; I408-Q410 VanDerWaalsContact C-N 3.29Å; I408-Q410 PolarHBondContact O-N 2.99Å
409	N	36.6	Very low	46.4	Very low	142 Å²	142	109.3 Å²	109.3	76%	0.759	58%	0.575	S	S	*	*	G	3₁₀ helix	trans	-76	-8.4	178	-70.9	-11.8	0	0	0	114.5	D407	D407-N409 PolarHBondContact O-N 3.48Å; D407-N409 VanDerWaalsContact O-N 3.16Å
410	Q	39.8	Very low	44.4	Very low	148 Å²	148	108.6 Å²	108.6	69%	0.692	57%	0.572	S	S	*	*	G	3₁₀ helix	trans	-91.9	-11.1	176.9	-70.5	-172.3	6.2	0	0	113.6	D407 I408	D407-Q410 PolarHBondContact O-N 3.41Å; D407-Q410 VanDerWaalsContact O-N 3.09Å; I408-Q410 VanDerWaalsContact C-N 3.29Å; I408-Q410 PolarHBondContact O-N 2.99Å
411	Y	41.6	Very low	42.7	Very low	104 Å²	104	113.9 Å²	113.9	41%	0.408	59%	0.594	S	S	.	*	G	3₁₀ helix	trans	-89.4	-7.4	-172.8	-86.1	-87.3	0	0	0	115.3	Q413 I414	Y411-Q413 PolarHBondContact O-N 2.94Å; Y411-I414 HydrophobicContact CD1-CD1 3.82Å; Y411-I414 HydrophobicContact CE1-CD1 3.91Å
412	E	43.3	Very low	41.9	Very low	169 Å²	169	115 Å²	115	79%	0.79	59%	0.59	S	S	*	*	G	3₁₀ helix	trans	-63.4	-6.3	175	-77.5	-172.3	155.5	0	0	114.3
413	Q	45.7	Very low	41.4	Very low	174 Å²	174	111.7 Å²	111.7	81%	0.813	56%	0.563	S	S	*	*	G	3₁₀ helix	trans	-100.2	-1	-175.6	-73.7	-173.8	-7.8	0	0	116.3	Y411 N415	Y411-Q413 PolarHBondContact O-N 2.94Å; Q413-N415 PolarHBondContact O-N 2.71Å
414	I	48.9	Very low	41.8	Very low	49 Å²	49	104.2 Å²	104.2	25%	0.251	53%	0.53	S	S	.	.			trans	-92.6	102.2	-178.6	-53.4	-179.9	0	0	0	110.4	Y411 R420 I423	Y411-I414 HydrophobicContact CD1-CD1 3.82Å; Y411-I414 HydrophobicContact CE1-CD1 3.91Å; I414-R420 PolarHBondContact O-NE 3.08Å; I414-R420 PolarHBondContact O-NH2 3.22Å; I414-I423 HydrophobicContact CD1-CD1 4Å; I414-I423 HydrophobicContact CG2-CD1 4.18Å
415	N	41.4	Very low	42.7	Very low	143 Å²	143	109.2 Å²	109.2	77%	0.765	54%	0.537	S	S	*	.			trans	-106	23.3	-168.3	-99.3	-16.2	0	0	0	115.7	Q413	Q413-N415 PolarHBondContact O-N 2.71Å
416	T	47.4	Very low	43.3	Very low	59 Å²	59	109.6 Å²	109.6	36%	0.362	54%	0.535	S	S	.	.			trans	-123.1	130.7	173.4	76.7	0	0	0	0	113.2	S418 E419 R420	T416-S418 VanDerWaalsContact C-N 3.27Å; T416-S418 PolarHBondContact O-N 3.33Å; T416-E419 PolarHBondContact O-N 2.9Å; T416-E419 WeakPolarHBondContact OG1-CB 3.38Å; T416-E419 VanDerWaalsContact OG1-CG 3.26Å; T416-E419 WeakPolarHBondContact OG1-CG 3.43Å; T416-E419 PolarHBondContact OG1-OE2 2.98Å; T416-R420 PolarHBondContact O-N 3.49Å; T416-R420 VanDerWaalsContact O-N 3.14Å
417	I	52	Low	44.2	Very low	136 Å²	136	107.8 Å²	107.8	70%	0.697	52%	0.518	S	S	*	.	H	α-helix	trans	-65.5	-28.5	-173.8	-63.2	168.1	0	0	0	112.2	K421	I417-K421 PolarHBondContact O-N 2.91Å
418	S	46.5	Very low	45	Very low	88 Å²	88	104.1 Å²	104.1	62%	0.615	50%	0.498	S	S	*	.	H	α-helix	trans	-76	-41.2	178.4	48.9	0	0	0	0	112.7	T416 E422	T416-S418 VanDerWaalsContact C-N 3.27Å; T416-S418 PolarHBondContact O-N 3.33Å; S418-E422 PolarHBondContact O-N 2.83Å
419	E	46.2	Very low	45.8	Very low	107 Å²	107	102.7 Å²	102.7	50%	0.5	50%	0.497	S	S	.	.	H	α-helix	trans	-69.4	-39.2	177.4	-68.6	172.5	157.7	0	0	110.5	T416 K421 E422 I423	T416-E419 PolarHBondContact O-N 2.9Å; T416-E419 WeakPolarHBondContact OG1-CB 3.38Å; T416-E419 VanDerWaalsContact OG1-CG 3.26Å; T416-E419 WeakPolarHBondContact OG1-CG 3.43Å; T416-E419 PolarHBondContact OG1-OE2 2.98Å; E419-K421 PolarHBondContact O-N 3.2Å; E419-E422 PolarHBondContact O-N 3.4Å; E419-E422 VanDerWaalsContact O-N 3.13Å; E419-I423 HydrophobicContact CB-CD1 4.28Å; E419-I423 WeakPolarHBondContact O-CB 3.33Å; E419-I423 WeakPolarHBondContact O-CD1 3.47Å; E419-I423 WeakPolarHBondContact O-CG1 3.34Å; E419-I423 PolarHBondContact O-N 3.04Å
420	R	41.6	Very low	47.4	Very low	73 Å²	73	98 Å²	98	28%	0.275	48%	0.475	S	S	.	.	H	α-helix	trans	-55.3	-44.2	173.7	-89	-169.4	-167.6	-150.8	1.5	114.2	D321 I414 T416 E422 I423 S424	D321-R420 WeakPolarHBondContact OD2-CB 3.31Å; D321-R420 WeakPolarHBondContact OD2-CG 3.39Å; I414-R420 PolarHBondContact O-NE 3.08Å; I414-R420 PolarHBondContact O-NH2 3.22Å; T416-R420 PolarHBondContact O-N 3.49Å; T416-R420 VanDerWaalsContact O-N 3.14Å; R420-E422 VanDerWaalsContact C-N 3.31Å; R420-E422 PolarHBondContact O-N 3.01Å; R420-I423 PolarHBondContact O-N 3.2Å; R420-S424 WeakPolarHBondContact O-CB 3.23Å; R420-S424 PolarHBondContact O-N 3.34Å; R420-S424 PolarHBondContact O-OG 2.84Å
421	K	43.3	Very low	49.5	Very low	148 Å²	148	91.5 Å²	91.5	64%	0.643	45%	0.445	S	S	*	.	H	α-helix	trans	-66.5	-28.7	176.6	-81.8	-175.2	178	179.1	0	114.2	I417 E419 S424	I417-K421 PolarHBondContact O-N 2.91Å; E419-K421 PolarHBondContact O-N 3.2Å; K421-S424 VanDerWaalsContact C-OG 3.29Å; K421-S424 VanDerWaalsContact CA-OG 3.31Å; K421-S424 WeakPolarHBondContact CA-OG 3.29Å; K421-S424 PolarHBondContact O-OG 3.16Å
422	E	42.8	Very low	51.5	Low	124 Å²	124	87.1 Å²	87.1	58%	0.579	43%	0.428	S	S	*	.	H	α-helix	trans	-85.9	-34.4	179.7	-153	172.4	-176.5	0	0	111.5	S418 E419 R420 K426	S418-E422 PolarHBondContact O-N 2.83Å; E419-E422 PolarHBondContact O-N 3.4Å; E419-E422 VanDerWaalsContact O-N 3.13Å; R420-E422 VanDerWaalsContact C-N 3.31Å; R420-E422 PolarHBondContact O-N 3.01Å; E422-K426 WeakPolarHBondContact O-CG 3.03Å; E422-K426 PolarHBondContact O-N 2.99Å
423	I	40.8	Very low	53.5	Low	51 Å²	51	84.3 Å²	84.3	26%	0.262	42%	0.415	S	S	.	.	H	α-helix	trans	-66	-48.6	173	-65.6	162.7	0	0	0	110.7	I414 E419 R420 R425 K426 E427	I414-I423 HydrophobicContact CD1-CD1 4Å; I414-I423 HydrophobicContact CG2-CD1 4.18Å; E419-I423 HydrophobicContact CB-CD1 4.28Å; E419-I423 WeakPolarHBondContact O-CB 3.33Å; E419-I423 WeakPolarHBondContact O-CD1 3.47Å; E419-I423 WeakPolarHBondContact O-CG1 3.34Å; E419-I423 PolarHBondContact O-N 3.04Å; R420-I423 PolarHBondContact O-N 3.2Å; I423-R425 VanDerWaalsContact C-N 3.31Å; I423-R425 PolarHBondContact O-N 3.13Å; I423-K426 WeakPolarHBondContact O-CA 3.46Å; I423-K426 WeakPolarHBondContact O-CB 3.33Å; I423-K426 PolarHBondContact O-N 3.14Å; I423-E427 HydrophobicContact CG2-CG 4.43Å; I423-E427 PolarHBondContact O-N 3.42Å
424	S	44.3	Very low	55.4	Low	15 Å²	15	79.1 Å²	79.1	11%	0.105	39%	0.391	C	S	.	.	H	α-helix	trans	-57.1	-38	177.3	48.8	0	0	0	0	114.1	V319 R420 K421 I428	V319-S424 VanDerWaalsContact CG1-O 3.25Å; V319-S424 WeakPolarHBondContact CG1-O 3.4Å; V319-S424 VanDerWaalsContact O-CA 3.22Å; V319-S424 WeakPolarHBondContact O-CA 3.11Å; V319-S424 WeakPolarHBondContact O-CB 3.33Å; R420-S424 WeakPolarHBondContact O-CB 3.23Å; R420-S424 PolarHBondContact O-N 3.34Å; R420-S424 PolarHBondContact O-OG 2.84Å; K421-S424 VanDerWaalsContact C-OG 3.29Å; K421-S424 VanDerWaalsContact CA-OG 3.31Å; K421-S424 WeakPolarHBondContact CA-OG 3.29Å; K421-S424 PolarHBondContact O-OG 3.16Å; S424-I428 PolarHBondContact O-N 3.24Å; S424-I428 VanDerWaalsContact O-N 3.13Å
425	R	47.7	Very low	57.4	Low	194 Å²	194	76.8 Å²	76.8	73%	0.732	38%	0.379	S	S	*	.	H	α-helix	trans	-68.9	-39.5	173.8	-77	-177.3	178	177.1	-0.8	112.2	I423 E427 A429	I423-R425 VanDerWaalsContact C-N 3.31Å; I423-R425 PolarHBondContact O-N 3.13Å; R425-E427 VanDerWaalsContact C-N 3.34Å; R425-A429 VanDerWaalsContact O-CB 3.22Å; R425-A429 WeakPolarHBondContact O-CB 3.45Å; R425-A429 PolarHBondContact O-N 3.07Å
426	K	50.2	Low	59.7	Low	139 Å²	139	73 Å²	73	60%	0.604	36%	0.358	S	S	*	.	H	α-helix	trans	-66.9	-34.3	177	-75.3	176.4	-178.4	173.2	0	112.1	E422 I423 A429 S430	E422-K426 WeakPolarHBondContact O-CG 3.03Å; E422-K426 PolarHBondContact O-N 2.99Å; I423-K426 WeakPolarHBondContact O-CA 3.46Å; I423-K426 WeakPolarHBondContact O-CB 3.33Å; I423-K426 PolarHBondContact O-N 3.14Å; K426-A429 WeakPolarHBondContact O-CB 3.12Å; K426-S430 PolarHBondContact O-N 3.12Å
427	E	50.5	Low	61.6	Low	39 Å²	39	76 Å²	76	18%	0.182	37%	0.371	C	S	.	.	H	α-helix	trans	-79	-36.1	179.5	-75.7	-179.4	-178.3	0	0	113.4	V319 I423 R425 A429 S430 L431	V319-E427 HydrophobicContact CB-CB 4.39Å; V319-E427 HydrophobicContact CG1-CB 3.44Å; V319-E427 VanDerWaalsContact CG1-CB 3.44Å; V319-E427 HydrophobicContact CG2-CB 4.07Å; I423-E427 HydrophobicContact CG2-CG 4.43Å; I423-E427 PolarHBondContact O-N 3.42Å; R425-E427 VanDerWaalsContact C-N 3.34Å; E427-A429 VanDerWaalsContact C-N 3.29Å; E427-S430 WeakPolarHBondContact O-CA 3.42Å; E427-S430 VanDerWaalsContact O-CB 3.23Å; E427-S430 WeakPolarHBondContact O-CB 3.37Å; E427-S430 PolarHBondContact O-N 3.29Å; E427-S430 PolarHBondContact O-OG 3.41Å; E427-L431 PolarHBondContact O-N 3.01Å; E427-L431 VanDerWaalsContact O-N 3.08Å
428	I	54	Low	63.3	Low	20 Å²	20	70.1 Å²	70.1	10%	0.103	34%	0.341	C	S	.	.	H	α-helix	trans	-67.4	-38.9	171.4	-91.1	144.7	0	0	0	108.7	V319 K320 S424 S430 L431 N432	V319-I428 HydrophobicContact CB-CD1 4.39Å; V319-I428 HydrophobicContact CB-CG1 4.08Å; V319-I428 HydrophobicContact CG1-CB 3.93Å; V319-I428 HydrophobicContact CG1-CD1 3.7Å; V319-I428 HydrophobicContact CG1-CG1 3.36Å; K320-I428 HydrophobicContact CD-CD1 3.48Å; K320-I428 VanDerWaalsContact CD-CD1 3.48Å; K320-I428 HydrophobicContact CG-CD1 3.9Å; S424-I428 PolarHBondContact O-N 3.24Å; S424-I428 VanDerWaalsContact O-N 3.13Å; I428-S430 PolarHBondContact O-N 3.08Å; I428-L431 PolarHBondContact O-N 3.21Å; I428-N432 PolarHBondContact O-N 2.98Å
429	A	57	Low	65.4	Low	35 Å²	35	66 Å²	66	29%	0.289	31%	0.312	S	S	.	.	H	α-helix	trans	-55.9	-41.5	168.6	0	0	0	0	0	109.9	R425 K426 E427 L431 N432 E433	R425-A429 VanDerWaalsContact O-CB 3.22Å; R425-A429 WeakPolarHBondContact O-CB 3.45Å; R425-A429 PolarHBondContact O-N 3.07Å; K426-A429 WeakPolarHBondContact O-CB 3.12Å; E427-A429 VanDerWaalsContact C-N 3.29Å; A429-L431 PolarHBondContact O-N 2.79Å; A429-N432 PolarHBondContact O-N 3.11Å; A429-E433 WeakPolarHBondContact O-CB 3.31Å; A429-E433 WeakPolarHBondContact O-CG 3.24Å; A429-E433 PolarHBondContact O-N 2.88Å
430	S	71.3	Confident	67.5	Low	43 Å²	43	62.3 Å²	62.3	30%	0.301	30%	0.297	S	S	.	.	H	α-helix	trans	-61.1	-38.9	176.6	97.4	0	0	0	0	113.9	K426 E427 I428 E433 Q434	K426-S430 PolarHBondContact O-N 3.12Å; E427-S430 WeakPolarHBondContact O-CA 3.42Å; E427-S430 VanDerWaalsContact O-CB 3.23Å; E427-S430 WeakPolarHBondContact O-CB 3.37Å; E427-S430 PolarHBondContact O-N 3.29Å; E427-S430 PolarHBondContact O-OG 3.41Å; I428-S430 PolarHBondContact O-N 3.08Å; S430-E433 PolarHBondContact O-N 2.89Å; S430-Q434 VanDerWaalsContact O-CG 3.29Å; S430-Q434 WeakPolarHBondContact O-CG 3.41Å; S430-Q434 PolarHBondContact O-N 3.23Å
431	L	82.7	Confident	69.8	Low	11 Å²	11	65.4 Å²	65.4	6%	0.058	32%	0.315	C	S	.	.	H	α-helix	trans	-73.4	-42	-179.8	-173.6	62.6	0	0	0	110.9	Q315 V316 F342 W397 I400 E427 I428 A429 E433 Q434 F435	Q315-L431 HydrophobicContact CG-CD2 4.36Å; V316-L431 HydrophobicContact CG2-CD2 4.48Å; F342-L431 HydrophobicContact CD2-CD2 4.08Å; F342-L431 HydrophobicContact CE2-CB 4.28Å; F342-L431 HydrophobicContact CE2-CD2 3.39Å; F342-L431 HydrophobicContact CE2-CG 3.7Å; F342-L431 HydrophobicContact CZ-CD2 3.7Å; F342-L431 HydrophobicContact CZ-CG 4.13Å; W397-L431 HydrophobicContact CZ3-CD1 4.28Å; W397-L431 HydrophobicContact CZ3-CD2 4.46Å; I400-L431 HydrophobicContact CD1-CD1 3.93Å; E427-L431 PolarHBondContact O-N 3.01Å; E427-L431 VanDerWaalsContact O-N 3.08Å; I428-L431 PolarHBondContact O-N 3.21Å; A429-L431 PolarHBondContact O-N 2.79Å; L431-E433 VanDerWaalsContact C-N 3.32Å; L431-Q434 PolarHBondContact O-N 2.91Å; L431-F435 HydrophobicContact CD1-CD1 4.37Å; L431-F435 HydrophobicContact CD1-CE1 3.95Å; L431-F435 HydrophobicContact CG-CE1 4.31Å; L431-F435 WeakPolarHBondContact O-CD1 3.48Å; L431-F435 PolarHBondContact O-N 3.44Å
432	N	83.8	Confident	72	Confident	13 Å²	13	58.4 Å²	58.4	7%	0.07	28%	0.284	C	S	.	.	H	α-helix	trans	-64.8	-35.8	173	-91.9	-49.4	0	0	0	112.1	F342 Y354 I428 A429 F435 L436	F342-N432 PolarHBondContact O-ND2 3.46Å; Y354-N432 PolarHBondContact OH-OD1 3.4Å; Y354-N432 VanDerWaalsContact OH-OD1 3.12Å; I428-N432 PolarHBondContact O-N 2.98Å; A429-N432 PolarHBondContact O-N 3.11Å; N432-F435 PolarHBondContact O-N 3.42Å; N432-L436 WeakPolarHBondContact O-CG 3.34Å; N432-L436 PolarHBondContact O-N 2.84Å
433	E	84.4	Confident	74.4	Confident	110 Å²	110	58.4 Å²	58.4	51%	0.514	28%	0.284	S	S	.	.	H	α-helix	trans	-63.9	-43.6	173.1	-78.2	168.5	-169	0	0	111.2	A429 S430 L431 F435 L436 I437	A429-E433 WeakPolarHBondContact O-CB 3.31Å; A429-E433 WeakPolarHBondContact O-CG 3.24Å; A429-E433 PolarHBondContact O-N 2.88Å; S430-E433 PolarHBondContact O-N 2.89Å; L431-E433 VanDerWaalsContact C-N 3.32Å; E433-F435 VanDerWaalsContact C-N 3.29Å; E433-F435 PolarHBondContact O-N 3.5Å; E433-L436 WeakPolarHBondContact O-CB 3.47Å; E433-L436 PolarHBondContact O-N 3.48Å; E433-L436 VanDerWaalsContact O-N 3.16Å; E433-I437 VanDerWaalsContact O-CG1 3.31Å; E433-I437 WeakPolarHBondContact O-CG1 3.49Å; E433-I437 PolarHBondContact O-N 2.86Å
434	Q	87	Confident	76.8	Confident	65 Å²	65	59.1 Å²	59.1	30%	0.304	29%	0.285	S	S	.	.	H	α-helix	trans	-59.5	-41.4	172.4	-74.2	174.9	47.7	0	0	111.5	I400 S430 L431 L436 I437 I438	I400-Q434 VanDerWaalsContact CG2-OE1 3.24Å; S430-Q434 VanDerWaalsContact O-CG 3.29Å; S430-Q434 WeakPolarHBondContact O-CG 3.41Å; S430-Q434 PolarHBondContact O-N 3.23Å; L431-Q434 PolarHBondContact O-N 2.91Å; Q434-L436 VanDerWaalsContact C-N 3.33Å; Q434-L436 PolarHBondContact O-N 3.17Å; Q434-I437 PolarHBondContact O-N 3.29Å; Q434-I438 WeakPolarHBondContact O-CB 3.31Å; Q434-I438 WeakPolarHBondContact O-CG1 3.49Å; Q434-I438 PolarHBondContact O-N 3.1Å
435	F	91	Very high	79	Confident	0 Å²	0	62.4 Å²	62.4	0%	0	30%	0.302	C	S	.	.	H	α-helix	trans	-67.4	-33.3	176.6	-80	26	0	0	0	112.4	F342 I346 Y354 F392 I393 C396 I400 L431 N432 E433 I437 G439	F342-F435 HydrophobicContact CE1-CE2 4.25Å; F342-F435 HydrophobicContact CE2-CE2 4.46Å; F342-F435 HydrophobicContact CZ-CD2 4.12Å; F342-F435 AromaticContact CZ-CE2 3.52Å; F342-F435 HydrophobicContact CZ-CE2 3.52Å; F342-F435 AromaticContact CZ-CZ 3.85Å; F342-F435 HydrophobicContact CZ-CZ 3.85Å; I346-F435 HydrophobicContact CD1-CD2 4.03Å; I346-F435 HydrophobicContact CD1-CE2 4.44Å; Y354-F435 HydrophobicContact CD1-CB 4.21Å; Y354-F435 HydrophobicContact CE1-CB 4.08Å; F392-F435 HydrophobicContact CD1-CD2 4.43Å; F392-F435 HydrophobicContact CE1-CB 4.47Å; F392-F435 AromaticContact CE1-CD2 3.65Å; F392-F435 HydrophobicContact CE1-CD2 3.65Å; F392-F435 HydrophobicContact CE1-CE2 4.29Å; F392-F435 HydrophobicContact CE1-CG 4.44Å; F392-F435 HydrophobicContact CZ-CB 4.26Å; F392-F435 HydrophobicContact CZ-CD2 4.17Å; I393-F435 HydrophobicContact CB-CE2 4.44Å; I393-F435 HydrophobicContact CG1-CE2 4.1Å; I393-F435 HydrophobicContact CG2-CE2 4.46Å; I393-F435 HydrophobicContact CG2-CZ 4.35Å; C396-F435 HydrophobicContact CB-CD1 3.63Å; C396-F435 HydrophobicContact CB-CD2 4.17Å; C396-F435 HydrophobicContact CB-CE1 3.55Å; C396-F435 HydrophobicContact CB-CE2 4.08Å; C396-F435 HydrophobicContact CB-CG 3.94Å; C396-F435 HydrophobicContact CB-CZ 3.78Å; I400-F435 HydrophobicContact CD1-CE1 4.11Å; L431-F435 HydrophobicContact CD1-CD1 4.37Å; L431-F435 HydrophobicContact CD1-CE1 3.95Å; L431-F435 HydrophobicContact CG-CE1 4.31Å; L431-F435 WeakPolarHBondContact O-CD1 3.48Å; L431-F435 PolarHBondContact O-N 3.44Å; N432-F435 PolarHBondContact O-N 3.42Å; E433-F435 VanDerWaalsContact C-N 3.29Å; E433-F435 PolarHBondContact O-N 3.5Å; F435-I437 VanDerWaalsContact C-N 3.31Å; F435-G439 WeakPolarHBondContact O-CA 3.36Å; F435-G439 PolarHBondContact O-N 3.28Å
436	L	88.6	Confident	81	Confident	63 Å²	63	55.3 Å²	55.3	33%	0.33	28%	0.278	S	S	.	.	H	α-helix	trans	-69.2	-28.2	172.8	-75.4	166.6	0	0	0	112.6	D353 Y354 N432 E433 Q434 P440	D353-L436 HydrophobicContact CB-CD2 3.99Å; Y354-L436 HydrophobicContact CD1-CD2 3.76Å; Y354-L436 HydrophobicContact CD1-CG 4.04Å; Y354-L436 HydrophobicContact CD2-CD2 4.25Å; Y354-L436 HydrophobicContact CE1-CD2 3.8Å; Y354-L436 HydrophobicContact CE1-CG 3.75Å; Y354-L436 HydrophobicContact CE2-CD2 4.25Å; Y354-L436 HydrophobicContact CG-CD2 4.03Å; N432-L436 WeakPolarHBondContact O-CG 3.34Å; N432-L436 PolarHBondContact O-N 2.84Å; E433-L436 WeakPolarHBondContact O-CB 3.47Å; E433-L436 PolarHBondContact O-N 3.48Å; E433-L436 VanDerWaalsContact O-N 3.16Å; Q434-L436 VanDerWaalsContact C-N 3.33Å; Q434-L436 PolarHBondContact O-N 3.17Å; L436-P440 WeakPolarHBondContact O-CD 3.29Å; L436-P440 WeakPolarHBondContact O-CG 3.34Å
437	I	87.2	Confident	83	Confident	121 Å²	121	48.7 Å²	48.7	62%	0.621	25%	0.25	S	C	*	.	H	α-helix	trans	-78.2	-47.9	175.3	-66.5	163.6	0	0	0	110.8	E433 Q434 F435	E433-I437 VanDerWaalsContact O-CG1 3.31Å; E433-I437 WeakPolarHBondContact O-CG1 3.49Å; E433-I437 PolarHBondContact O-N 2.86Å; Q434-I437 PolarHBondContact O-N 3.29Å; F435-I437 VanDerWaalsContact C-N 3.31Å
438	I	88.6	Confident	84.9	Confident	14 Å²	14	48.8 Å²	48.8	7%	0.072	25%	0.25	C	S	.	.	H	α-helix	trans	-77.4	-39.7	-175.1	-65.4	167.4	0	0	0	111.7	C396 R399 I400 Q434 E441 L442	C396-I438 HydrophobicContact CB-CG2 4.42Å; R399-I438 HydrophobicContact CB-CD1 4.29Å; R399-I438 HydrophobicContact CB-CG2 3.74Å; R399-I438 HydrophobicContact CG-CG2 4.42Å; I400-I438 HydrophobicContact CG1-CD1 3.76Å; Q434-I438 WeakPolarHBondContact O-CB 3.31Å; Q434-I438 WeakPolarHBondContact O-CG1 3.49Å; Q434-I438 PolarHBondContact O-N 3.1Å; I438-E441 WeakPolarHBondContact O-CB 3.44Å; I438-E441 PolarHBondContact O-N 3.03Å; I438-L442 HydrophobicContact CG2-CD2 4.37Å
439	G	90	Very high	86.5	Confident	0 Å²	0	53.9 Å²	53.9	0%	0	27%	0.272	C	S	.	.	G	3₁₀ helix	trans	-55.6	-42.2	-170.8	0	0	0	0	0	114.8	Y354 F435 E441 L442	Y354-G439 CarbonylContact O-C 2.88Å; Y354-G439 WeakPolarHBondContact O-CA 3.27Å; F435-G439 WeakPolarHBondContact O-CA 3.36Å; F435-G439 PolarHBondContact O-N 3.28Å; G439-E441 PolarHBondContact O-N 3.29Å; G439-L442 WeakPolarHBondContact O-CB 3.44Å; G439-L442 WeakPolarHBondContact O-CG 3.13Å; G439-L442 PolarHBondContact O-N 2.87Å
440	P	91.5	Very high	87.9	Confident	30 Å²	30	52.5 Å²	52.5	20%	0.195	26%	0.26	C	S	.	.	G	3₁₀ helix	trans	-61.4	-21.7	174.9	-27.3	36.8	0	0	0	114.8	I175 Y354 S356 L436 L442	I175-P440 HydrophobicContact CD1-CG 4.24Å; I175-P440 HydrophobicContact CG2-CB 4.45Å; Y354-P440 WeakPolarHBondContact O-CD 3.41Å; Y354-P440 VanDerWaalsContact O-N 3.16Å; S356-P440 WeakPolarHBondContact CB-O 3.35Å; L436-P440 WeakPolarHBondContact O-CD 3.29Å; L436-P440 WeakPolarHBondContact O-CG 3.34Å; P440-L442 VanDerWaalsContact C-N 3.32Å
441	E	89.5	Confident	88.7	Confident	138 Å²	138	50.5 Å²	50.5	65%	0.645	25%	0.245	S	C	*	.	G	3₁₀ helix	trans	-82.5	-10.7	176.3	-54.3	-174.5	161	0	0	112.8	I438 G439 E443	I438-E441 WeakPolarHBondContact O-CB 3.44Å; I438-E441 PolarHBondContact O-N 3.03Å; G439-E441 PolarHBondContact O-N 3.29Å; E441-E443 PolarHBondContact O-N 3.48Å
442	L	90.2	Very high	88.8	Confident	1 Å²	1	56.9 Å²	56.9	1%	0.005	27%	0.273	C	S	.	.			trans	-73.6	126.3	179.3	-58	-176.8	0	0	0	111.4	L355 T359 F392 L395 I438 G439 P440 F447	L355-L442 HydrophobicContact CD2-CB 4.36Å; L355-L442 HydrophobicContact CD2-CD1 4.26Å; T359-L442 PolarHBondContact OG1-O 3.35Å; F392-L442 HydrophobicContact CD2-CD1 3.8Å; F392-L442 HydrophobicContact CE2-CD1 3.99Å; L395-L442 HydrophobicContact CB-CD1 3.84Å; L395-L442 HydrophobicContact CB-CD2 3.89Å; L395-L442 HydrophobicContact CD1-CD1 4.37Å; I438-L442 HydrophobicContact CG2-CD2 4.37Å; G439-L442 WeakPolarHBondContact O-CB 3.44Å; G439-L442 WeakPolarHBondContact O-CG 3.13Å; G439-L442 PolarHBondContact O-N 2.87Å; P440-L442 VanDerWaalsContact C-N 3.32Å; L442-F447 HydrophobicContact CB-CE2 4.06Å; L442-F447 HydrophobicContact CD1-CE2 4.21Å; L442-F447 HydrophobicContact CD1-CZ 4.35Å
443	E	91.3	Very high	88.7	Confident	124 Å²	124	62 Å²	62	58%	0.579	30%	0.295	S	S	*	.			trans	-87.9	144.1	178.5	-62.8	-169.8	166.4	0	0	111.3	E441 D445 D446	E441-E443 PolarHBondContact O-N 3.48Å; E443-D445 PolarHBondContact O-N 3.19Å; E443-D445 VanDerWaalsContact O-N 3.11Å; E443-D446 WeakPolarHBondContact O-CB 2.94Å; E443-D446 PolarHBondContact O-N 3.1Å; E443-D446 VanDerWaalsContact O-N 3.09Å
444	K	92.6	Very high	88.7	Confident	66 Å²	66	59 Å²	59	29%	0.287	28%	0.279	S	S	.	.	H	α-helix	trans	-56	-28.5	174.7	72.8	-175.7	-176.6	169.1	0	112.9	T122 T359 Y362 D446 F447 Q448	T122-K444 PolarHBondContact OG1-NZ 2.91Å; T359-K444 HydrophobicContact CG2-CB 4.42Å; T359-K444 PolarHBondContact OG1-N 3.38Å; T359-K444 VanDerWaalsContact OG1-N 3.07Å; Y362-K444 HydrophobicContact CD1-CB 4.14Å; Y362-K444 HydrophobicContact CG-CB 4.09Å; K444-D446 VanDerWaalsContact C-N 3.3Å; K444-D446 PolarHBondContact O-N 3.34Å; K444-F447 WeakPolarHBondContact O-CB 2.99Å; K444-F447 PolarHBondContact O-N 3.44Å; K444-Q448 WeakPolarHBondContact O-CG 3.3Å; K444-Q448 PolarHBondContact O-N 3.38Å
445	D	90.6	Very high	88.8	Confident	84 Å²	84	56 Å²	56	45%	0.449	26%	0.264	S	S	.	.	H	α-helix	trans	-68.9	-31.8	-178	-68.4	3.4	0	0	0	110.8	E443 Q448 F449	E443-D445 PolarHBondContact O-N 3.19Å; E443-D445 VanDerWaalsContact O-N 3.11Å; D445-Q448 PolarHBondContact O-N 3.48Å; D445-F449 VanDerWaalsContact O-CB 3.32Å; D445-F449 WeakPolarHBondContact O-CB 3.47Å; D445-F449 PolarHBondContact O-N 2.66Å
446	D	88.3	Confident	88.6	Confident	45 Å²	45	58.1 Å²	58.1	24%	0.241	28%	0.276	C	S	.	.	H	α-helix	trans	-62.3	-44.2	171.5	-72.5	-22.9	0	0	0	111.2	L395 R399 E443 K444 F449 L450	L395-D446 HydrophobicContact CD1-CB 3.83Å; L395-D446 HydrophobicContact CD2-CB 3.99Å; R399-D446 IonicContact CZ-OD2 2.93Å; R399-D446 IonicContact NH1-OD2 2.88Å; R399-D446 IonicContact NH2-OD2 3.28Å; R399-D446 PolarHBondContact NH2-OD2 3.38Å; E443-D446 WeakPolarHBondContact O-CB 2.94Å; E443-D446 PolarHBondContact O-N 3.1Å; E443-D446 VanDerWaalsContact O-N 3.09Å; K444-D446 VanDerWaalsContact C-N 3.3Å; K444-D446 PolarHBondContact O-N 3.34Å; D446-F449 PolarHBondContact O-N 2.97Å; D446-L450 WeakPolarHBondContact O-CG 3.05Å; D446-L450 PolarHBondContact O-N 3.05Å
447	F	92.8	Very high	88.2	Confident	0 Å²	0	59.3 Å²	59.3	0%	0	28%	0.28	C	S	.	.	H	α-helix	trans	-64.7	-46.1	175.7	-75.6	-97.9	0	0	0	111.1	L355 T359 Y362 I363 F388 I391 F392 L395 L442 K444 F449 L450 I451	L355-F447 HydrophobicContact CD1-CZ 4.39Å; L355-F447 HydrophobicContact CD2-CE2 4.23Å; L355-F447 HydrophobicContact CD2-CZ 4.1Å; T359-F447 HydrophobicContact CG2-CD2 3.63Å; T359-F447 HydrophobicContact CG2-CE2 3.52Å; T359-F447 HydrophobicContact CG2-CZ 4.32Å; Y362-F447 HydrophobicContact CD1-CB 4.37Å; Y362-F447 HydrophobicContact CE1-CB 3.71Å; I363-F447 HydrophobicContact CD1-CD1 4.25Å; I363-F447 HydrophobicContact CD1-CE1 3.87Å; I363-F447 HydrophobicContact CD1-CZ 4.26Å; F388-F447 AromaticContact CD1-CD1 3.83Å; F388-F447 HydrophobicContact CD1-CD1 3.83Å; F388-F447 HydrophobicContact CD1-CE1 4.33Å; F388-F447 HydrophobicContact CE1-CD1 4.27Å; I391-F447 HydrophobicContact CB-CD1 4.17Å; I391-F447 HydrophobicContact CB-CE1 4.24Å; I391-F447 HydrophobicContact CG2-CD1 3.35Å; I391-F447 HydrophobicContact CG2-CE1 3.59Å; I391-F447 HydrophobicContact CG2-CG 3.98Å; I391-F447 HydrophobicContact CG2-CZ 4.37Å; F392-F447 HydrophobicContact CB-CE1 4.24Å; F392-F447 HydrophobicContact CB-CZ 4.2Å; F392-F447 HydrophobicContact CD2-CZ 4.25Å; L395-F447 HydrophobicContact CD1-CD2 3.91Å; L395-F447 HydrophobicContact CD1-CE2 3.77Å; L395-F447 HydrophobicContact CD1-CG 4.35Å; L395-F447 HydrophobicContact CD1-CZ 4.11Å; L442-F447 HydrophobicContact CB-CE2 4.06Å; L442-F447 HydrophobicContact CD1-CE2 4.21Å; L442-F447 HydrophobicContact CD1-CZ 4.35Å; K444-F447 WeakPolarHBondContact O-CB 2.99Å; K444-F447 PolarHBondContact O-N 3.44Å; F447-F449 VanDerWaalsContact C-N 3.26Å; F447-F449 PolarHBondContact O-N 3.32Å; F447-L450 PolarHBondContact O-N 2.97Å; F447-I451 WeakPolarHBondContact O-CB 3.33Å; F447-I451 VanDerWaalsContact O-CG1 3.27Å; F447-I451 WeakPolarHBondContact O-CG1 3.47Å; F447-I451 PolarHBondContact O-N 3.26Å
448	Q	91.2	Very high	88	Confident	42 Å²	42	55.6 Å²	55.6	20%	0.196	26%	0.262	C	S	.	.	H	α-helix	trans	-59.2	-40.1	178.3	-73.3	178.3	-1.7	0	0	112	N120 Y362 K444 D445 K452	N120-Q448 PolarHBondContact ND2-O 3.46Å; N120-Q448 VanDerWaalsContact OD1-CA 3.29Å; N120-Q448 WeakPolarHBondContact OD1-CA 3.29Å; N120-Q448 WeakPolarHBondContact OD1-CG 3.32Å; Y362-Q448 HydrophobicContact CD2-CG 4.27Å; Y362-Q448 HydrophobicContact CE1-CG 4.24Å; Y362-Q448 HydrophobicContact CE2-CG 3.46Å; Y362-Q448 VanDerWaalsContact CE2-CG 3.46Å; Y362-Q448 VanDerWaalsContact CZ-CG 3.46Å; Y362-Q448 WeakPolarHBondContact OH-CG 3.1Å; K444-Q448 WeakPolarHBondContact O-CG 3.3Å; K444-Q448 PolarHBondContact O-N 3.38Å; D445-Q448 PolarHBondContact O-N 3.48Å; Q448-K452 VanDerWaalsContact O-CB 3.25Å; Q448-K452 WeakPolarHBondContact O-CB 3.44Å; Q448-K452 PolarHBondContact O-N 3.01Å
449	F	87.2	Confident	87.8	Confident	126 Å²	126	55 Å²	55	55%	0.553	26%	0.259	S	S	*	.	H	α-helix	trans	-63.4	-49.4	175.6	176.5	-97.8	0	0	0	111.7	D445 D446 F447 K452 K453	D445-F449 VanDerWaalsContact O-CB 3.32Å; D445-F449 WeakPolarHBondContact O-CB 3.47Å; D445-F449 PolarHBondContact O-N 2.66Å; D446-F449 PolarHBondContact O-N 2.97Å; F447-F449 VanDerWaalsContact C-N 3.26Å; F447-F449 PolarHBondContact O-N 3.32Å; F449-K452 WeakPolarHBondContact O-CB 3.19Å; F449-K452 PolarHBondContact O-N 2.96Å; F449-K453 HydrophobicContact CE1-CD 4.01Å; F449-K453 HydrophobicContact CZ-CD 4.16Å; F449-K453 WeakPolarHBondContact O-CB 3.31Å; F449-K453 PolarHBondContact O-N 2.62Å
450	L	85.9	Confident	87.5	Confident	7 Å²	7	56.5 Å²	56.5	4%	0.037	27%	0.266	C	S	.	.	H	α-helix	trans	-68.1	-37.4	-179.1	-71.1	173.3	0	0	0	112.7	I391 F394 L395 D446 F447 K453 Y454	I391-L450 HydrophobicContact CB-CD1 4.48Å; I391-L450 HydrophobicContact CD1-CB 3.96Å; I391-L450 HydrophobicContact CG1-CB 4Å; I391-L450 HydrophobicContact CG1-CD1 4.44Å; I391-L450 HydrophobicContact CG2-CB 4.18Å; I391-L450 HydrophobicContact CG2-CD1 3.64Å; F394-L450 HydrophobicContact CD1-CD1 3.8Å; F394-L450 HydrophobicContact CE1-CD1 4.06Å; F394-L450 HydrophobicContact CE1-CD2 4.2Å; L395-L450 HydrophobicContact CD1-CD1 4.04Å; L395-L450 HydrophobicContact CD2-CD1 3.64Å; L395-L450 HydrophobicContact CG-CD1 3.7Å; D446-L450 WeakPolarHBondContact O-CG 3.05Å; D446-L450 PolarHBondContact O-N 3.05Å; F447-L450 PolarHBondContact O-N 2.97Å; L450-K453 PolarHBondContact O-N 2.97Å; L450-Y454 HydrophobicContact CD2-CD2 3.91Å; L450-Y454 HydrophobicContact CD2-CE2 3.59Å; L450-Y454 WeakPolarHBondContact O-CD2 3.45Å; L450-Y454 PolarHBondContact O-N 2.95Å
451	I	88.4	Confident	86.8	Confident	0 Å²	0	55.9 Å²	55.9	0%	0	26%	0.261	C	S	.	.	I	π-helix	trans	-59.5	-49.4	169.9	-68.4	-70.2	0	0	0	110	F119 N120 F388 I391 F447 K453 F455 I456 I459	F119-I451 HydrophobicContact CE1-CG2 4.5Å; F119-I451 HydrophobicContact CE2-CG2 4.19Å; F119-I451 HydrophobicContact CZ-CG2 3.66Å; N120-I451 HydrophobicContact CB-CG2 4.36Å; F388-I451 HydrophobicContact CE1-CD1 3.97Å; F388-I451 HydrophobicContact CE1-CG1 4.04Å; F388-I451 HydrophobicContact CZ-CD1 4.05Å; F388-I451 HydrophobicContact CZ-CG1 4.32Å; I391-I451 HydrophobicContact CD1-CD1 3.51Å; I391-I451 HydrophobicContact CD1-CG1 3.75Å; F447-I451 WeakPolarHBondContact O-CB 3.33Å; F447-I451 VanDerWaalsContact O-CG1 3.27Å; F447-I451 WeakPolarHBondContact O-CG1 3.47Å; F447-I451 PolarHBondContact O-N 3.26Å; I451-K453 PolarHBondContact O-N 3.31Å; I451-F455 HydrophobicContact CD1-CB 4.35Å; I451-F455 HydrophobicContact CD1-CD2 4.25Å; I451-F455 CarbonylContact O-C 3.43Å; I451-F455 PolarHBondContact O-N 3.04Å; I451-I456 HydrophobicContact CG2-CD1 4.44Å; I451-I456 PolarHBondContact O-N 3.42Å; I451-I459 HydrophobicContact CD1-CD1 3.69Å
452	K	85.6	Confident	86.4	Confident	146 Å²	146	50 Å²	50	64%	0.635	23%	0.234	S	C	*	.	I	π-helix	trans	-59.1	-37.7	179	-172.6	176.4	178.7	-178.7	0	112.4	Q448 F449 I456	Q448-K452 VanDerWaalsContact O-CB 3.25Å; Q448-K452 WeakPolarHBondContact O-CB 3.44Å; Q448-K452 PolarHBondContact O-N 3.01Å; F449-K452 WeakPolarHBondContact O-CB 3.19Å; F449-K452 PolarHBondContact O-N 2.96Å; K452-I456 VanDerWaalsContact O-CG2 3.3Å; K452-I456 WeakPolarHBondContact O-CG2 3.42Å
453	K	81	Confident	85.8	Confident	121 Å²	121	50 Å²	50	53%	0.526	23%	0.234	S	C	.	.	I	π-helix	trans	-78.2	-42.1	-175.5	-174.4	175.9	175.5	-160.5	0	113.1	F449 L450 I451	F449-K453 HydrophobicContact CE1-CD 4.01Å; F449-K453 HydrophobicContact CZ-CD 4.16Å; F449-K453 WeakPolarHBondContact O-CB 3.31Å; F449-K453 PolarHBondContact O-N 2.62Å; L450-K453 PolarHBondContact O-N 2.97Å; I451-K453 PolarHBondContact O-N 3.31Å
454	Y	85	Confident	84.8	Confident	47 Å²	47	45.4 Å²	45.4	18%	0.184	22%	0.215	C	C	.	.	I	π-helix	trans	-113.3	-35	-168.6	-66.2	-76.6	0	0	0	113.8	Y303 I304 L450	Y303-Y454 HydrophobicContact CD1-CD1 4.08Å; Y303-Y454 AromaticContact CE1-CD1 3.86Å; Y303-Y454 HydrophobicContact CE1-CD1 3.86Å; Y303-Y454 HydrophobicContact CE1-CG 4.36Å; Y303-Y454 VanDerWaalsContact CE1-O 3.31Å; Y303-Y454 WeakPolarHBondContact CE1-O 3.45Å; I304-Y454 HydrophobicContact CG1-CD2 4.28Å; I304-Y454 HydrophobicContact CG1-CG 4.3Å; I304-Y454 HydrophobicContact CG2-CD2 4.46Å; I304-Y454 HydrophobicContact CG2-CE2 3.99Å; I304-Y454 PolarHBondContact O-OH 3.36Å; L450-Y454 HydrophobicContact CD2-CD2 3.91Å; L450-Y454 HydrophobicContact CD2-CE2 3.59Å; L450-Y454 WeakPolarHBondContact O-CD2 3.45Å; L450-Y454 PolarHBondContact O-N 2.95Å
455	F	89.1	Confident	83.6	Confident	0 Å²	0	44.5 Å²	44.5	0%	0	22%	0.224	C	C	.	.	I	π-helix	trans	-123.6	5.6	-165	-52.8	-67.9	0	0	0	114.4	Q300 Y303 I304 C387 I391 I451 M457 I459	Q300-F455 HydrophobicContact CB-CE1 4.11Å; Q300-F455 HydrophobicContact CB-CZ 4.06Å; Q300-F455 HydrophobicContact CG-CE1 4.36Å; Y303-F455 HydrophobicContact CD1-CD1 4.48Å; Y303-F455 AromaticContact CD1-CE1 3.79Å; Y303-F455 HydrophobicContact CD1-CE1 3.79Å; Y303-F455 HydrophobicContact CD1-CZ 4.26Å; Y303-F455 HydrophobicContact CE1-CE1 4.38Å; I304-F455 HydrophobicContact CD1-CE2 3.81Å; I304-F455 HydrophobicContact CD1-CZ 3.84Å; I304-F455 HydrophobicContact CG1-CE2 3.9Å; I304-F455 HydrophobicContact CG1-CZ 3.67Å; C387-F455 HydrophobicContact CB-CD2 4.31Å; C387-F455 HydrophobicContact CB-CG 4.28Å; I391-F455 HydrophobicContact CD1-CD2 3.93Å; I391-F455 HydrophobicContact CD1-CE2 3.93Å; I391-F455 HydrophobicContact CG1-CD2 4.41Å; I391-F455 HydrophobicContact CG1-CE2 3.89Å; I451-F455 HydrophobicContact CD1-CB 4.35Å; I451-F455 HydrophobicContact CD1-CD2 4.25Å; I451-F455 CarbonylContact O-C 3.43Å; I451-F455 PolarHBondContact O-N 3.04Å; F455-M457 PolarHBondContact O-N 2.68Å; F455-I459 HydrophobicContact CB-CD1 3.6Å; F455-I459 HydrophobicContact CB-CG1 4.08Å; F455-I459 WeakPolarHBondContact O-CB 3.38Å; F455-I459 WeakPolarHBondContact O-CG1 3.41Å; F455-I459 PolarHBondContact O-N 3.15Å
456	I	85.2	Confident	82	Confident	46 Å²	46	44.5 Å²	44.5	24%	0.236	23%	0.227	C	C	.	.	H	α-helix	trans	-61.3	-46.5	-170.6	-166.5	79.4	0	0	0	112	F119 N120 I451 K452 F460	F119-I456 HydrophobicContact CD1-CD1 4.01Å; F119-I456 HydrophobicContact CE1-CD1 3.36Å; F119-I456 HydrophobicContact CE1-CG1 4.03Å; F119-I456 HydrophobicContact CZ-CD1 4.1Å; N120-I456 HydrophobicContact CB-CD1 4.35Å; I451-I456 HydrophobicContact CG2-CD1 4.44Å; I451-I456 PolarHBondContact O-N 3.42Å; K452-I456 VanDerWaalsContact O-CG2 3.3Å; K452-I456 WeakPolarHBondContact O-CG2 3.42Å; I456-F460 WeakPolarHBondContact O-CB 3.05Å; I456-F460 PolarHBondContact O-N 3.45Å
457	M	81.1	Confident	80.2	Confident	87 Å²	87	47.2 Å²	47.2	43%	0.429	24%	0.239	S	C	.	.	H	α-helix	trans	-71.3	-46.5	-177.1	-70.8	-60.5	100	0	0	111.1	F455 F460 C461	F455-M457 PolarHBondContact O-N 2.68Å; M457-F460 PolarHBondContact O-N 3.19Å; M457-C461 VanDerWaalsContact O-CB 3.29Å; M457-C461 WeakPolarHBondContact O-CB 3.48Å; M457-C461 PolarHBondContact O-N 2.94Å; M457-C461 PolarHBondContact O-SG 2.88Å; M457-C461 VanDerWaalsContact O-SG 3.36Å
458	D	83.1	Confident	77.5	Confident	43 Å²	43	56.5 Å²	56.5	23%	0.23	28%	0.282	C	S	.	.	H	α-helix	trans	-61	-51.7	-178.4	-64.3	-9.7	0	0	0	111.5	Y383 C461 L462 Y469	Y383-D458 HydrophobicContact CE1-CB 4.36Å; Y383-D458 WeakPolarHBondContact OH-CB 3.11Å; Y383-D458 PolarHBondContact OH-OD2 3.29Å; D458-C461 PolarHBondContact O-N 3.44Å; D458-L462 WeakPolarHBondContact O-CB 3.36Å; D458-L462 PolarHBondContact O-N 3.22Å; D458-Y469 PolarHBondContact O-OH 3.41Å
459	I	85.5	Confident	74.8	Confident	2 Å²	2	59.6 Å²	59.6	1%	0.01	29%	0.293	C	S	.	.	H	α-helix	trans	-68	-40.1	179.9	-61	171.4	0	0	0	110.5	F119 Y383 I384 C387 I451 F455 C461 L462 L463	F119-I459 HydrophobicContact CD2-CG2 4.09Å; F119-I459 HydrophobicContact CE1-CB 4.43Å; F119-I459 HydrophobicContact CE1-CG2 4.45Å; F119-I459 HydrophobicContact CE2-CB 3.95Å; F119-I459 HydrophobicContact CE2-CG2 3.28Å; F119-I459 HydrophobicContact CZ-CB 3.6Å; F119-I459 HydrophobicContact CZ-CD1 4.42Å; F119-I459 HydrophobicContact CZ-CG2 3.5Å; F119-I459 VanDerWaalsContact CZ-CG2 3.5Å; Y383-I459 HydrophobicContact CE1-CG1 3.93Å; I384-I459 HydrophobicContact CD1-CG2 3.94Å; I384-I459 HydrophobicContact CG1-CG1 4.44Å; I384-I459 HydrophobicContact CG1-CG2 4.05Å; C387-I459 HydrophobicContact CB-CD1 4.22Å; I451-I459 HydrophobicContact CD1-CD1 3.69Å; F455-I459 HydrophobicContact CB-CD1 3.6Å; F455-I459 HydrophobicContact CB-CG1 4.08Å; F455-I459 WeakPolarHBondContact O-CB 3.38Å; F455-I459 WeakPolarHBondContact O-CG1 3.41Å; F455-I459 PolarHBondContact O-N 3.15Å; I459-C461 PolarHBondContact O-N 2.97Å; I459-L462 WeakPolarHBondContact O-CB 3.44Å; I459-L462 PolarHBondContact O-N 2.95Å; I459-L463 HydrophobicContact CG2-CD1 3.72Å; I459-L463 HydrophobicContact CG2-CG 4.02Å; I459-L463 WeakPolarHBondContact O-CB 3.42Å; I459-L463 WeakPolarHBondContact O-CG 3.35Å; I459-L463 PolarHBondContact O-N 3.46Å
460	F	82.4	Confident	72.1	Confident	32 Å²	32	59.7 Å²	59.7	14%	0.14	30%	0.299	C	S	.	.	H	α-helix	trans	-59.9	-49.9	177.5	-176	-96.9	0	0	0	110.9	F119 I456 M457 L462 L463 T464 W487	F119-F460 HydrophobicContact CD1-CB 4.11Å; F119-F460 AromaticContact CD1-CD2 3.88Å; F119-F460 HydrophobicContact CD1-CD2 3.88Å; F119-F460 HydrophobicContact CE1-CB 4Å; I456-F460 WeakPolarHBondContact O-CB 3.05Å; I456-F460 PolarHBondContact O-N 3.45Å; M457-F460 PolarHBondContact O-N 3.19Å; F460-L462 VanDerWaalsContact C-N 3.32Å; F460-L462 PolarHBondContact O-N 3.4Å; F460-L463 PolarHBondContact O-N 3.03Å; F460-L463 VanDerWaalsContact O-N 3.1Å; F460-T464 HydrophobicContact CD1-CG2 4.32Å; F460-T464 HydrophobicContact CD2-CG2 4.17Å; F460-T464 HydrophobicContact CE1-CG2 3.89Å; F460-T464 HydrophobicContact CE2-CG2 3.75Å; F460-T464 HydrophobicContact CG-CG2 4.44Å; F460-T464 HydrophobicContact CZ-CG2 3.58Å; F460-T464 PolarHBondContact O-N 2.85Å; F460-T464 PolarHBondContact O-OG1 3.27Å; F460-W487 HydrophobicContact CE1-CH2 4.07Å; F460-W487 HydrophobicContact CE1-CZ2 4.05Å; F460-W487 HydrophobicContact CE2-CH2 4.26Å; F460-W487 AromaticContact CZ-CH2 3.41Å; F460-W487 HydrophobicContact CZ-CH2 3.41Å; F460-W487 VanDerWaalsContact CZ-CH2 3.41Å; F460-W487 AromaticContact CZ-CZ2 3.8Å; F460-W487 HydrophobicContact CZ-CZ2 3.8Å; F460-W487 HydrophobicContact CZ-CZ3 4.24Å
461	C	77.5	Confident	69.7	Low	16 Å²	16	63.7 Å²	63.7	11%	0.108	33%	0.333	C	S	.	.	H	α-helix	trans	-59.3	-40.1	177.6	-76.1	0	0	0	0	112.7	M457 D458 I459 G465 T466	M457-C461 VanDerWaalsContact O-CB 3.29Å; M457-C461 WeakPolarHBondContact O-CB 3.48Å; M457-C461 PolarHBondContact O-N 2.94Å; M457-C461 PolarHBondContact O-SG 2.88Å; M457-C461 VanDerWaalsContact O-SG 3.36Å; D458-C461 PolarHBondContact O-N 3.44Å; I459-C461 PolarHBondContact O-N 2.97Å; C461-G465 VanDerWaalsContact O-CA 3.29Å; C461-G465 WeakPolarHBondContact O-CA 3.17Å; C461-G465 PolarHBondContact O-N 2.66Å; C461-T466 PolarHBondContact O-N 2.87Å
462	L	80.5	Confident	67	Low	14 Å²	14	71.3 Å²	71.3	7%	0.073	37%	0.373	C	S	.	.	H	α-helix	trans	-58.7	-46.9	172.9	-172	65.6	0	0	0	112.1	Y383 I384 D458 I459 F460 Y469	Y383-L462 HydrophobicContact CD1-CD2 3.73Å; Y383-L462 HydrophobicContact CE1-CD2 4.48Å; Y383-L462 HydrophobicContact CG-CD2 4.44Å; I384-L462 HydrophobicContact CD1-CD2 4.07Å; I384-L462 HydrophobicContact CG1-CD2 3.9Å; D458-L462 WeakPolarHBondContact O-CB 3.36Å; D458-L462 PolarHBondContact O-N 3.22Å; I459-L462 WeakPolarHBondContact O-CB 3.44Å; I459-L462 PolarHBondContact O-N 2.95Å; F460-L462 VanDerWaalsContact C-N 3.32Å; F460-L462 PolarHBondContact O-N 3.4Å; L462-Y469 HydrophobicContact CB-CE2 3.93Å; L462-Y469 WeakPolarHBondContact CB-OH 3.45Å; L462-Y469 HydrophobicContact CD1-CD2 4.37Å; L462-Y469 HydrophobicContact CD1-CE1 4.46Å; L462-Y469 HydrophobicContact CD1-CE2 3.58Å; L462-Y469 HydrophobicContact CG-CE2 4.37Å
463	L	77.2	Confident	64.3	Low	2 Å²	2	67.8 Å²	67.8	1%	0.01	37%	0.368	C	S	.	.	H	α-helix	trans	-73.6	-37.3	-176	-68.1	178	0	0	0	112.6	F119 C370 G373 A374 I384 I459 F460	F119-L463 HydrophobicContact CB-CD1 4.27Å; F119-L463 HydrophobicContact CD2-CD1 3.49Å; F119-L463 VanDerWaalsContact CD2-CD1 3.49Å; F119-L463 HydrophobicContact CE2-CD1 4.06Å; F119-L463 HydrophobicContact CG-CD1 3.97Å; C370-L463 HydrophobicContact CB-CD2 3.93Å; G373-L463 CarbonylContact C-O 3.57Å; G373-L463 VanDerWaalsContact CA-O 3.23Å; G373-L463 WeakPolarHBondContact CA-O 3.35Å; A374-L463 PolarHBondContact N-O 3.21Å; I384-L463 HydrophobicContact CD1-CD2 3.83Å; I384-L463 HydrophobicContact CD1-CG 4.34Å; I459-L463 HydrophobicContact CG2-CD1 3.72Å; I459-L463 HydrophobicContact CG2-CG 4.02Å; I459-L463 WeakPolarHBondContact O-CB 3.42Å; I459-L463 WeakPolarHBondContact O-CG 3.35Å; I459-L463 PolarHBondContact O-N 3.46Å; F460-L463 PolarHBondContact O-N 3.03Å; F460-L463 VanDerWaalsContact O-N 3.1Å
464	T	71.2	Confident	61.8	Low	28 Å²	28	65.5 Å²	65.5	17%	0.172	37%	0.366	C	S	.	.	H	α-helix	trans	-95.4	-12.5	-176.4	55.9	0	0	0	0	114.2	F460 T466	F460-T464 HydrophobicContact CD1-CG2 4.32Å; F460-T464 HydrophobicContact CD2-CG2 4.17Å; F460-T464 HydrophobicContact CE1-CG2 3.89Å; F460-T464 HydrophobicContact CE2-CG2 3.75Å; F460-T464 HydrophobicContact CG-CG2 4.44Å; F460-T464 HydrophobicContact CZ-CG2 3.58Å; F460-T464 PolarHBondContact O-N 2.85Å; F460-T464 PolarHBondContact O-OG1 3.27Å; T464-T466 VanDerWaalsContact C-N 3.31Å; T464-T466 WeakPolarHBondContact OG1-CG2 3.44Å; T464-T466 PolarHBondContact OG1-OG1 3.06Å
465	G	67.9	Low	59.1	Low	46 Å²	46	70.5 Å²	70.5	47%	0.474	40%	0.395	S	S	.	.	T	Hydrogen-bonded Turn	trans	69	26.7	-177.7	0	0	0	0	0	113.4	C461 Q467	C461-G465 VanDerWaalsContact O-CA 3.29Å; C461-G465 WeakPolarHBondContact O-CA 3.17Å; C461-G465 PolarHBondContact O-N 2.66Å; G465-Q467 PolarHBondContact O-N 3.17Å
466	T	56.3	Low	56.2	Low	84 Å²	84	75 Å²	75	52%	0.515	42%	0.418	S	S	.	.			trans	-84.6	1.1	-167.3	41.4	0	0	0	0	115.9	C461 T464	C461-T466 PolarHBondContact O-N 2.87Å; T464-T466 VanDerWaalsContact C-N 3.31Å; T464-T466 WeakPolarHBondContact OG1-CG2 3.44Å; T464-T466 PolarHBondContact OG1-OG1 3.06Å
467	Q	49.8	Very low	53.4	Low	103 Å²	103	77.4 Å²	77.4	48%	0.481	44%	0.44	S	S	.	.	S	Bend	trans	-157	145.9	171.9	-102.6	167.1	6.6	0	0	110.8	G465 Y469 L476	G465-Q467 PolarHBondContact O-N 3.17Å; Q467-Y469 PolarHBondContact O-N 3.19Å; Q467-Y469 VanDerWaalsContact O-N 3.14Å; Q467-L476 VanDerWaalsContact OE1-CD2 3.31Å
468	Q	37.1	Very low	51	Low	195 Å²	195	79.9 Å²	79.9	91%	0.911	46%	0.455	S	S	*	.			trans	-59.3	113.6	176.6	-78	177.4	-30.3	0	0	110	N470	Q468-N470 PolarHBondContact O-N 2.98Å
469	Y	34.5	Very low	48.4	Very low	107 Å²	107	85.1 Å²	85.1	42%	0.42	48%	0.483	S	S	.	.			trans	-62.4	96.9	168.2	-102.6	-93.5	0	0	0	109.3	D458 L462 Q467 A471	D458-Y469 PolarHBondContact O-OH 3.41Å; L462-Y469 HydrophobicContact CB-CE2 3.93Å; L462-Y469 WeakPolarHBondContact CB-OH 3.45Å; L462-Y469 HydrophobicContact CD1-CD2 4.37Å; L462-Y469 HydrophobicContact CD1-CE1 4.46Å; L462-Y469 HydrophobicContact CD1-CE2 3.58Å; L462-Y469 HydrophobicContact CG-CE2 4.37Å; Q467-Y469 PolarHBondContact O-N 3.19Å; Q467-Y469 VanDerWaalsContact O-N 3.14Å; Y469-A471 PolarHBondContact O-N 3.24Å
470	N	30.2	Very low	45.8	Very low	127 Å²	127	93.6 Å²	93.6	68%	0.679	52%	0.522	S	S	*	.			trans	-74.2	103.8	153.4	-97	-13.8	0	0	0	106.4	Q468 N472 S473	Q468-N470 PolarHBondContact O-N 2.98Å; N470-N472 PolarHBondContact O-N 3.07Å; N470-S473 PolarHBondContact O-N 2.99Å
471	A	34.8	Very low	43.4	Very low	91 Å²	91	97.7 Å²	97.7	75%	0.752	55%	0.545	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.1	2.1	-175.1	0	0	0	0	0	115.9	Y469	Y469-A471 PolarHBondContact O-N 3.24Å
472	N	32.5	Very low	41.4	Very low	160 Å²	160	103.7 Å²	103.7	86%	0.856	58%	0.575	S	S	*	*	T	Hydrogen-bonded Turn	trans	-127	0.7	-172.8	-72.3	-17.9	0	0	0	116.1	N470	N470-N472 PolarHBondContact O-N 3.07Å
473	S	29.5	Very low	39.1	Very low	73 Å²	73	107.5 Å²	107.5	51%	0.51	60%	0.599	S	S	.	*			trans	-131.5	103.3	-175.2	62.4	0	0	0	0	113.8	N470 L475	N470-S473 PolarHBondContact O-N 2.99Å; S473-L475 PolarHBondContact O-N 3.27Å
474	C	27.7	Very low	37.1	Very low	73 Å²	73	112.1 Å²	112.1	49%	0.493	63%	0.631	S	S	.	*			trans	-72.9	69.3	162.9	-178.9	0	0	0	0	109.6
475	L	27.9	Very low	35.5	Very low	151 Å²	151	115.5 Å²	115.5	79%	0.791	65%	0.652	S	S	*	*			trans	-153.8	88.9	174.5	-81.7	176.5	0	0	0	109.7	S473	S473-L475 PolarHBondContact O-N 3.27Å
476	L	27.9	Very low	33.8	Very low	94 Å²	94	114.9 Å²	114.9	49%	0.492	65%	0.646	S	S	.	*			trans	-89.8	105.3	149.7	-76.8	171.8	0	0	0	107.1	Q467	Q467-L476 VanDerWaalsContact OE1-CD2 3.31Å
477	S	27.2	Very low	32.7	Very low	98 Å²	98	116.8 Å²	116.8	69%	0.685	64%	0.644	S	S	*	*			trans	-56.2	137.5	169.9	46	0	0	0	0	110.8	D479	S477-D479 PolarHBondContact O-N 3.49Å
478	N	29.9	Very low	31.9	Very low	139 Å²	139	115.8 Å²	115.8	74%	0.743	65%	0.648	S	S	*	*	T	Hydrogen-bonded Turn	trans	-59.8	7.9	-171.2	-77.6	-35	0	0	0	117.9
479	D	28.2	Very low	31.7	Very low	153 Å²	153	110.2 Å²	110.2	82%	0.818	63%	0.631	S	S	*	*	T	Hydrogen-bonded Turn	trans	-102.6	0.8	-161.1	-78.5	-22.3	0	0	0	117.3	S477	S477-D479 PolarHBondContact O-N 3.49Å
480	E	32.5	Very low	31.5	Very low	179 Å²	179	110.2 Å²	110.2	84%	0.836	64%	0.642	S	S	*	*			trans	-128.7	31.5	176.7	-77.5	-169.5	156.5	0	0	114.5	L482	E480-L482 PolarHBondContact O-N 3.44Å
481	L	31.6	Very low	31.5	Very low	118 Å²	118	109.1 Å²	109.1	62%	0.618	64%	0.636	S	S	*	*			trans	-64.8	98.4	173.9	-95.7	150.2	0	0	0	111.2	T483	L481-T483 PolarHBondContact O-N 2.8Å
482	L	34.4	Very low	31.4	Very low	142 Å²	142	112.6 Å²	112.6	74%	0.743	64%	0.637	S	S	*	*			trans	-53.4	107.8	158.5	-82.2	164.7	0	0	0	108.2	E480	E480-L482 PolarHBondContact O-N 3.44Å
483	T	32.8	Very low	31.2	Very low	94 Å²	94	112.4 Å²	112.4	58%	0.577	63%	0.628	S	S	*	*			trans	-54.8	146.2	-176.1	46.5	0	0	0	0	111.7	L481 T485 G486	L481-T483 PolarHBondContact O-N 2.8Å; T483-T485 PolarHBondContact O-N 3.41Å; T483-T485 PolarHBondContact OG1-OG1 3.21Å; T483-T485 VanDerWaalsContact OG1-OG1 3.04Å; T483-G486 PolarHBondContact O-N 3.25Å
484	S	35.9	Very low	31.2	Very low	99 Å²	99	113.7 Å²	113.7	69%	0.692	64%	0.637	S	S	*	*	H	α-helix	trans	-54.3	-15	-177.6	73.6	0	0	0	0	114.9	S488	S484-S488 PolarHBondContact O-OG 2.99Å
485	T	36.6	Very low	31.4	Very low	99 Å²	99	114.3 Å²	114.3	61%	0.607	63%	0.63	S	S	*	*	H	α-helix	trans	-69.7	-30.3	172.6	43.7	0	0	0	0	113.5	T483	T483-T485 PolarHBondContact O-N 3.41Å; T483-T485 PolarHBondContact OG1-OG1 3.21Å; T483-T485 VanDerWaalsContact OG1-OG1 3.04Å
486	G	32.3	Very low	32	Very low	34 Å²	34	112.9 Å²	112.9	35%	0.351	62%	0.622	S	S	.	*	H	α-helix	trans	-67.3	-40.8	177.5	0	0	0	0	0	113.1	T483 S489 T490	T483-G486 PolarHBondContact O-N 3.25Å; G486-S489 PolarHBondContact O-N 3.45Å; G486-S489 PolarHBondContact O-OG 2.94Å; G486-T490 PolarHBondContact O-OG1 2.87Å
487	W	34.1	Very low	32.4	Very low	123 Å²	123	113.1 Å²	113.1	47%	0.466	62%	0.623	S	S	.	*	H	α-helix	trans	-68.8	-35.7	-179.5	-77.7	96.1	0	0	0	113.2	F460 S489 T490	F460-W487 HydrophobicContact CE1-CH2 4.07Å; F460-W487 HydrophobicContact CE1-CZ2 4.05Å; F460-W487 HydrophobicContact CE2-CH2 4.26Å; F460-W487 AromaticContact CZ-CH2 3.41Å; F460-W487 HydrophobicContact CZ-CH2 3.41Å; F460-W487 VanDerWaalsContact CZ-CH2 3.41Å; F460-W487 AromaticContact CZ-CZ2 3.8Å; F460-W487 HydrophobicContact CZ-CZ2 3.8Å; F460-W487 HydrophobicContact CZ-CZ3 4.24Å; W487-S489 VanDerWaalsContact C-N 3.26Å; W487-S489 PolarHBondContact O-N 3.1Å; W487-T490 PolarHBondContact O-N 3.48Å
488	S	32.3	Very low	32.8	Very low	82 Å²	82	112.9 Å²	112.9	57%	0.573	61%	0.614	S	S	*	*	H	α-helix	trans	-66.2	-27.3	-178.8	-59.2	0	0	0	0	113	S484	S484-S488 PolarHBondContact O-OG 2.99Å
489	S	32.1	Very low	32.9	Very low	79 Å²	79	111 Å²	111	55%	0.552	61%	0.609	S	S	*	*	H	α-helix	trans	-78.1	-23.6	179.7	74.6	0	0	0	0	114.1	G486 W487	G486-S489 PolarHBondContact O-N 3.45Å; G486-S489 PolarHBondContact O-OG 2.94Å; W487-S489 VanDerWaalsContact C-N 3.26Å; W487-S489 PolarHBondContact O-N 3.1Å
490	T	31.1	Very low	33.3	Very low	106 Å²	106	107.7 Å²	107.7	65%	0.65	60%	0.598	S	S	*	*	H	α-helix	trans	-86.7	-24.7	-171.7	-52.2	0	0	0	0	112.2	G486 W487 Q492	G486-T490 PolarHBondContact O-OG1 2.87Å; W487-T490 PolarHBondContact O-N 3.48Å; T490-Q492 PolarHBondContact O-N 3.37Å
491	L	31	Very low	33.6	Very low	105 Å²	105	107 Å²	107	55%	0.55	59%	0.592	S	S	.	*	T	Hydrogen-bonded Turn	trans	-82.8	-5.7	-176	-73.6	165.1	0	0	0	114.7	K493	L491-K493 PolarHBondContact O-N 2.82Å
492	Q	32	Very low	34	Very low	163 Å²	163	104.2 Å²	104.2	76%	0.762	57%	0.573	S	S	*	*	T	Hydrogen-bonded Turn	trans	-86.3	1.2	-169	-110.9	-178.8	2.6	0	0	116.6	T490	T490-Q492 PolarHBondContact O-N 3.37Å
493	K	28.7	Very low	34.2	Very low	157 Å²	157	103.5 Å²	103.5	68%	0.683	57%	0.565	S	S	*	*			trans	-144.4	98	-166.6	-66.1	179.7	-178.1	172.6	0	114.1	L491	L491-K493 PolarHBondContact O-N 2.82Å
494	S	28.4	Very low	35	Very low	99 Å²	99	106 Å²	106	69%	0.692	57%	0.569	S	S	*	*			trans	175.5	116.5	143.8	30.1	0	0	0	0	114
495	Y	33.6	Very low	35.4	Very low	87 Å²	87	108 Å²	108	34%	0.341	57%	0.568	S	S	.	*			trans	-138.9	140.9	154.9	-61.1	-101.4	0	0	0	105.6	I92 E95 A96	I92-Y495 HydrophobicContact CG2-CE2 3.99Å; I92-Y495 WeakPolarHBondContact CG2-OH 3.4Å; I92-Y495 WeakPolarHBondContact O-CE1 3.36Å; I92-Y495 PolarHBondContact O-OH 3.5Å; E95-Y495 HydrophobicContact CB-CD1 4.35Å; E95-Y495 HydrophobicContact CB-CE1 3.82Å; A96-Y495 HydrophobicContact CB-CE1 3.63Å; A96-Y495 HydrophobicContact CB-CE2 4.5Å; A96-Y495 VanDerWaalsContact CB-CZ 3.46Å; A96-Y495 WeakPolarHBondContact CB-OH 3.41Å
496	L	39	Very low	36.1	Very low	120 Å²	120	108.1 Å²	108.1	63%	0.628	56%	0.557	S	S	*	*				178.8	153.5	70.4	-102.9	131	0	0	0	109.1
497	I	36.9	Very low	37.3	Very low	99 Å²	99	112 Å²	112	51%	0.508	57%	0.569	S	S	.	*			trans	-126.6	169.9	165.8	-74.2	164.7	0	0	0	108.6	R502	I497-R502 PolarHBondContact O-NE 3.26Å; I497-R502 PolarHBondContact O-NH1 2.84Å; I497-R502 PolarHBondContact O-NH2 3.31Å
498	D	35.8	Very low	38.5	Very low	94 Å²	94	111.7 Å²	111.7	50%	0.503	58%	0.576	S	S	.	*			trans	-35.5	123.6	-170.1	-163.1	-20.7	0	0	0	120.3	S500 R502	D498-S500 PolarHBondContact OD1-N 3.37Å; D498-S500 PolarHBondContact OD1-OG 2.97Å; D498-R502 WeakPolarHBondContact O-CD 3.47Å; D498-R502 WeakPolarHBondContact O-CG 3.47Å; D498-R502 PolarHBondContact O-NE 3.05Å
499	P	32.8	Very low	39.3	Very low	98 Å²	98	112.6 Å²	112.6	64%	0.636	57%	0.571	S	S	*	*	S	Bend	trans	-76.7	-19.2	-177.5	-15.2	30.1	0	0	0	118.2	R502	P499-R502 PolarHBondContact O-N 3.32Å
500	S	35.3	Very low	40.6	Very low	84 Å²	84	114.8 Å²	114.8	59%	0.587	57%	0.568	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77	-42.3	-162.1	56.8	0	0	0	0	114	D498 R502	D498-S500 PolarHBondContact OD1-N 3.37Å; D498-S500 PolarHBondContact OD1-OG 2.97Å; S500-R502 VanDerWaalsContact C-N 3.28Å; S500-R502 PolarHBondContact O-N 3.02Å
501	K	39.4	Very low	42.3	Very low	166 Å²	166	112.5 Å²	112.5	72%	0.722	56%	0.56	S	S	*	*	T	Hydrogen-bonded Turn	trans	-74.4	-16.1	174.2	-69	-173.9	174.6	-174.7	0	113.9
502	R	38.7	Very low	43.8	Very low	58 Å²	58	113.3 Å²	113.3	22%	0.219	56%	0.561	C	S	.	*	H	α-helix	trans	-75.4	-26.5	-177.3	-61	-177.6	-169.3	-145.4	-19.3	113.1	E95 I497 D498 P499 S500 E504 R506	E95-R502 IonicContact OE2-NH1 2.78Å; I497-R502 PolarHBondContact O-NE 3.26Å; I497-R502 PolarHBondContact O-NH1 2.84Å; I497-R502 PolarHBondContact O-NH2 3.31Å; D498-R502 WeakPolarHBondContact O-CD 3.47Å; D498-R502 WeakPolarHBondContact O-CG 3.47Å; D498-R502 PolarHBondContact O-NE 3.05Å; P499-R502 PolarHBondContact O-N 3.32Å; S500-R502 VanDerWaalsContact C-N 3.28Å; S500-R502 PolarHBondContact O-N 3.02Å; R502-E504 VanDerWaalsContact C-N 3.35Å; R502-R506 WeakPolarHBondContact O-CB 3.14Å; R502-R506 WeakPolarHBondContact O-CD 3.37Å; R502-R506 WeakPolarHBondContact O-CG 3.32Å; R502-R506 PolarHBondContact O-N 3.41Å; R502-R506 VanDerWaalsContact O-N 3.16Å
503	K	40.5	Very low	45.4	Very low	128 Å²	128	109.5 Å²	109.5	56%	0.557	55%	0.545	S	S	*	.	H	α-helix	trans	-67.6	-38.3	-177.5	-167.3	178.2	177.4	-172.7	0	111.6	L507	K503-L507 HydrophobicContact CG-CD1 4.48Å; K503-L507 WeakPolarHBondContact O-CD1 3.36Å; K503-L507 WeakPolarHBondContact O-CG 3.49Å; K503-L507 PolarHBondContact O-N 3.07Å
504	E	48.9	Very low	47.3	Very low	145 Å²	145	108 Å²	108	68%	0.678	54%	0.541	S	S	*	.	H	α-helix	trans	-75.6	-43	-177	-156.2	168.7	-157.7	0	0	112	R502 R506 L507 L508	R502-E504 VanDerWaalsContact C-N 3.35Å; E504-R506 PolarHBondContact O-N 3.44Å; E504-L507 PolarHBondContact O-N 2.96Å; E504-L508 WeakPolarHBondContact O-CG 3.26Å; E504-L508 PolarHBondContact O-N 2.81Å
505	Q	44.9	Very low	49.4	Very low	142 Å²	142	111 Å²	111	66%	0.664	54%	0.537	S	S	*	.	H	α-helix	trans	-64.9	-36.7	174.6	-74.9	-178.5	-24.8	0	0	113	L508 H509	Q505-L508 PolarHBondContact O-N 2.67Å; Q505-H509 WeakPolarHBondContact O-CB 3.33Å; Q505-H509 PolarHBondContact O-N 3.49Å
506	R	49.8	Very low	51	Low	102 Å²	102	111.9 Å²	111.9	39%	0.385	55%	0.547	S	S	.	.	H	α-helix	trans	-63	-45.7	174.5	-76.6	171.2	179.7	177.1	-1.3	111.5	E95 R502 E504 L508 H509 Y510	E95-R506 IonicContact OE1-CZ 3.31Å; E95-R506 IonicContact OE1-NE 2.75Å; E95-R506 IonicContact OE1-NH2 3.71Å; E95-R506 PolarHBondContact OE1-NH2 3.5Å; E95-R506 IonicContact OE2-NH2 3.95Å; E95-R506 PolarHBondContact OE2-NH2 2.95Å; R502-R506 WeakPolarHBondContact O-CB 3.14Å; R502-R506 WeakPolarHBondContact O-CD 3.37Å; R502-R506 WeakPolarHBondContact O-CG 3.32Å; R502-R506 PolarHBondContact O-N 3.41Å; R502-R506 VanDerWaalsContact O-N 3.16Å; E504-R506 PolarHBondContact O-N 3.44Å; R506-L508 VanDerWaalsContact C-N 3.34Å; R506-L508 PolarHBondContact O-N 2.98Å; R506-H509 PolarHBondContact O-N 3.45Å; R506-Y510 HydrophobicContact CB-CD2 4.46Å; R506-Y510 HydrophobicContact CB-CE2 4.28Å; R506-Y510 WeakPolarHBondContact O-CD2 3.44Å; R506-Y510 PolarHBondContact O-N 3.04Å
507	L	58.2	Low	52.4	Low	115 Å²	115	113 Å²	113	60%	0.602	54%	0.543	S	S	*	.	H	α-helix	trans	-62.1	-40.9	178	-78.4	161.9	0	0	0	112	K503 E504 A511	K503-L507 HydrophobicContact CG-CD1 4.48Å; K503-L507 WeakPolarHBondContact O-CD1 3.36Å; K503-L507 WeakPolarHBondContact O-CG 3.49Å; K503-L507 PolarHBondContact O-N 3.07Å; E504-L507 PolarHBondContact O-N 2.96Å; L507-A511 WeakPolarHBondContact O-CB 3.4Å; L507-A511 PolarHBondContact O-N 3.37Å
508	L	58.7	Low	54.4	Low	116 Å²	116	113 Å²	113	61%	0.607	54%	0.544	S	S	*	.	H	α-helix	trans	-63.7	-44.5	175.4	-74.9	165.2	0	0	0	112.1	E504 Q505 R506 A511 E512	E504-L508 WeakPolarHBondContact O-CG 3.26Å; E504-L508 PolarHBondContact O-N 2.81Å; Q505-L508 PolarHBondContact O-N 2.67Å; R506-L508 VanDerWaalsContact C-N 3.34Å; R506-L508 PolarHBondContact O-N 2.98Å; L508-A511 PolarHBondContact O-N 3.48Å; L508-E512 WeakPolarHBondContact O-CB 3.48Å; L508-E512 PolarHBondContact O-N 3.46Å
509	H	50.2	Low	56.3	Low	101 Å²	101	112 Å²	112	47%	0.468	54%	0.542	S	S	.	.	H	α-helix	trans	-66.4	-40	179.9	-169.1	59.4	0	0	0	112.7	Q505 R506 E512 L513	Q505-H509 WeakPolarHBondContact O-CB 3.33Å; Q505-H509 PolarHBondContact O-N 3.49Å; R506-H509 PolarHBondContact O-N 3.45Å; H509-E512 PolarHBondContact O-N 3.5Å; H509-L513 WeakPolarHBondContact O-CG 3.34Å; H509-L513 PolarHBondContact O-N 3.23Å
510	Y	58.5	Low	58.4	Low	126 Å²	126	113.4 Å²	113.4	49%	0.494	54%	0.54	S	S	.	.	H	α-helix	trans	-64.8	-41.2	174.8	-74.2	-59.3	0	0	0	112.2	R506 E512 L513 E514	R506-Y510 HydrophobicContact CB-CD2 4.46Å; R506-Y510 HydrophobicContact CB-CE2 4.28Å; R506-Y510 WeakPolarHBondContact O-CD2 3.44Å; R506-Y510 PolarHBondContact O-N 3.04Å; Y510-E512 VanDerWaalsContact C-N 3.27Å; Y510-E512 PolarHBondContact O-N 3.12Å; Y510-L513 PolarHBondContact O-N 3.36Å; Y510-E514 WeakPolarHBondContact O-CB 3.33Å; Y510-E514 PolarHBondContact O-N 2.92Å
511	A	67.5	Low	60.4	Low	58 Å²	58	113.3 Å²	113.3	48%	0.479	53%	0.533	S	S	.	.	H	α-helix	trans	-62.8	-35.6	175.3	0	0	0	0	0	112.1	L507 L508 R515	L507-A511 WeakPolarHBondContact O-CB 3.4Å; L507-A511 PolarHBondContact O-N 3.37Å; L508-A511 PolarHBondContact O-N 3.48Å; A511-R515 WeakPolarHBondContact O-CB 3.33Å; A511-R515 PolarHBondContact O-N 3.14Å
512	E	62.8	Low	62.4	Low	122 Å²	122	111 Å²	111	57%	0.57	52%	0.524	S	S	*	.	H	α-helix	trans	-72.1	-43.7	177.2	-168.8	165.5	-158.7	0	0	112.5	L508 H509 Y510 E514 R515 L516	L508-E512 WeakPolarHBondContact O-CB 3.48Å; L508-E512 PolarHBondContact O-N 3.46Å; H509-E512 PolarHBondContact O-N 3.5Å; Y510-E512 VanDerWaalsContact C-N 3.27Å; Y510-E512 PolarHBondContact O-N 3.12Å; E512-E514 VanDerWaalsContact C-N 3.33Å; E512-E514 PolarHBondContact O-N 2.74Å; E512-R515 WeakPolarHBondContact O-CB 3.47Å; E512-R515 PolarHBondContact O-N 3.45Å; E512-L516 WeakPolarHBondContact O-CG 3.5Å; E512-L516 PolarHBondContact O-N 3.29Å
513	L	64.1	Low	64.2	Low	82 Å²	82	113.1 Å²	113.1	43%	0.429	54%	0.539	S	S	.	.	H	α-helix	trans	-61.2	-40.7	174.1	-74.9	173.6	0	0	0	112.2	H509 Y510 L516 R517	H509-L513 WeakPolarHBondContact O-CG 3.34Å; H509-L513 PolarHBondContact O-N 3.23Å; Y510-L513 PolarHBondContact O-N 3.36Å; L513-L516 PolarHBondContact O-N 3Å; L513-R517 WeakPolarHBondContact O-CB 3.46Å; L513-R517 PolarHBondContact O-N 3.33Å
514	E	68.3	Low	66	Low	127 Å²	127	113.3 Å²	113.3	59%	0.593	54%	0.544	S	S	*	.	H	α-helix	trans	-65.8	-39.6	175.5	-172.9	165.2	-158.9	0	0	111.5	Y510 E512 R517 N518	Y510-E514 WeakPolarHBondContact O-CB 3.33Å; Y510-E514 PolarHBondContact O-N 2.92Å; E512-E514 VanDerWaalsContact C-N 3.33Å; E512-E514 PolarHBondContact O-N 2.74Å; E514-R517 PolarHBondContact O-N 2.92Å; E514-N518 WeakPolarHBondContact O-CB 3.33Å; E514-N518 VanDerWaalsContact O-CG 3.29Å; E514-N518 PolarHBondContact O-N 3.43Å; E514-N518 PolarHBondContact O-ND2 3.4Å
515	R	74.1	Confident	67.6	Low	160 Å²	160	113.2 Å²	113.2	60%	0.604	54%	0.541	S	S	*	.	H	α-helix	trans	-59.2	-48.9	171.2	-117.3	-170.3	160	128.1	3	111.6	A511 E512 R517 N518 T519 P609	A511-R515 WeakPolarHBondContact O-CB 3.33Å; A511-R515 PolarHBondContact O-N 3.14Å; E512-R515 WeakPolarHBondContact O-CB 3.47Å; E512-R515 PolarHBondContact O-N 3.45Å; R515-R517 PolarHBondContact O-N 3.43Å; R515-N518 PolarHBondContact O-N 2.95Å; R515-T519 PolarHBondContact O-N 2.99Å; R515-T519 PolarHBondContact O-OG1 2.98Å; R515-P609 VanDerWaalsContact NH2-CB 3.35Å
516	L	66.6	Low	69.2	Low	107 Å²	107	109.7 Å²	109.7	56%	0.56	53%	0.525	S	S	*	.	H	α-helix	trans	-61	-43.9	179.9	-73.3	172.6	0	0	0	111.7	E512 L513 T519 E520	E512-L516 WeakPolarHBondContact O-CG 3.5Å; E512-L516 PolarHBondContact O-N 3.29Å; L513-L516 PolarHBondContact O-N 3Å; L516-T519 WeakPolarHBondContact O-CB 3.37Å; L516-T519 PolarHBondContact O-N 3.36Å; L516-T519 VanDerWaalsContact O-N 3.16Å; L516-E520 PolarHBondContact O-N 3.49Å
517	R	69.1	Low	70.8	Confident	143 Å²	143	109.6 Å²	109.6	54%	0.54	53%	0.529	S	S	.	.	H	α-helix	trans	-65.4	-43	178.8	-166.4	177.8	-174.8	-178.4	3.3	112.7	L513 E514 R515 T519 E520 D521	L513-R517 WeakPolarHBondContact O-CB 3.46Å; L513-R517 PolarHBondContact O-N 3.33Å; E514-R517 PolarHBondContact O-N 2.92Å; R515-R517 PolarHBondContact O-N 3.43Å; R517-T519 PolarHBondContact O-N 3.08Å; R517-E520 PolarHBondContact O-N 2.66Å; R517-D521 PolarHBondContact O-N 3.08Å
518	N	78.6	Confident	72	Confident	98 Å²	98	110.6 Å²	110.6	52%	0.524	53%	0.531	S	S	.	.	H	α-helix	trans	-61.8	-34.3	173.6	-74.3	-29.9	0	0	0	111.7	E514 R515 H522	E514-N518 WeakPolarHBondContact O-CB 3.33Å; E514-N518 VanDerWaalsContact O-CG 3.29Å; E514-N518 PolarHBondContact O-N 3.43Å; E514-N518 PolarHBondContact O-ND2 3.4Å; R515-N518 PolarHBondContact O-N 2.95Å; N518-H522 WeakPolarHBondContact O-CB 3.35Å; N518-H522 PolarHBondContact O-N 3.46Å; N518-H522 VanDerWaalsContact O-N 3.08Å
519	T	76	Confident	73.2	Confident	75 Å²	75	109.2 Å²	109.2	46%	0.46	52%	0.521	S	S	.	.	H	α-helix	trans	-70.9	-40.4	176.3	-41.2	0	0	0	0	111.3	R515 L516 R517 H522 L523	R515-T519 PolarHBondContact O-N 2.99Å; R515-T519 PolarHBondContact O-OG1 2.98Å; L516-T519 WeakPolarHBondContact O-CB 3.37Å; L516-T519 PolarHBondContact O-N 3.36Å; L516-T519 VanDerWaalsContact O-N 3.16Å; R517-T519 PolarHBondContact O-N 3.08Å; T519-H522 PolarHBondContact O-N 3.4Å; T519-L523 WeakPolarHBondContact O-CB 3.45Å; T519-L523 WeakPolarHBondContact O-CG 3.42Å; T519-L523 PolarHBondContact O-N 2.89Å
520	E	76	Confident	74.6	Confident	126 Å²	126	108.2 Å²	108.2	59%	0.589	52%	0.519	S	S	*	.	H	α-helix	trans	-62.7	-46.8	174.9	-175.4	176.6	-161.2	0	0	111.9	L516 R517 H522 L523 M524	L516-E520 PolarHBondContact O-N 3.49Å; R517-E520 PolarHBondContact O-N 2.66Å; E520-H522 VanDerWaalsContact C-N 3.26Å; E520-H522 PolarHBondContact O-N 3.34Å; E520-L523 WeakPolarHBondContact O-CB 3.24Å; E520-L523 PolarHBondContact O-N 2.98Å; E520-L523 VanDerWaalsContact O-N 3.16Å; E520-M524 PolarHBondContact O-N 3.42Å
521	D	77.8	Confident	75.8	Confident	83 Å²	83	105.6 Å²	105.6	44%	0.444	51%	0.513	S	S	.	.	H	α-helix	trans	-61	-37	175	-83.8	-12	0	0	0	111.8	R517 K525	R517-D521 PolarHBondContact O-N 3.08Å; D521-K525 WeakPolarHBondContact O-CG 3.47Å; D521-K525 PolarHBondContact O-N 3.44Å; D521-K525 VanDerWaalsContact O-N 3.09Å
522	H	80	Confident	76.7	Confident	117 Å²	117	105.6 Å²	105.6	54%	0.542	51%	0.507	S	S	.	.	H	α-helix	trans	-68	-42.4	175	-155.8	70.9	0	0	0	111.7	N518 T519 E520 K525 M526	N518-H522 WeakPolarHBondContact O-CB 3.35Å; N518-H522 PolarHBondContact O-N 3.46Å; N518-H522 VanDerWaalsContact O-N 3.08Å; T519-H522 PolarHBondContact O-N 3.4Å; E520-H522 VanDerWaalsContact C-N 3.26Å; E520-H522 PolarHBondContact O-N 3.34Å; H522-K525 PolarHBondContact O-N 3.37Å; H522-M526 WeakPolarHBondContact O-CG 3.19Å; H522-M526 PolarHBondContact O-N 3.06Å
523	L	76.7	Confident	77.7	Confident	102 Å²	102	103.1 Å²	103.1	53%	0.534	49%	0.493	S	S	.	.	H	α-helix	trans	-62.4	-42.8	175.2	-75.9	167.2	0	0	0	111.9	T519 E520 K525 M526 Q527	T519-L523 WeakPolarHBondContact O-CB 3.45Å; T519-L523 WeakPolarHBondContact O-CG 3.42Å; T519-L523 PolarHBondContact O-N 2.89Å; E520-L523 WeakPolarHBondContact O-CB 3.24Å; E520-L523 PolarHBondContact O-N 2.98Å; E520-L523 VanDerWaalsContact O-N 3.16Å; L523-K525 PolarHBondContact O-N 2.88Å; L523-M526 HydrophobicContact CD2-CE 3.63Å; L523-M526 HydrophobicContact CG-CE 4.42Å; L523-M526 PolarHBondContact O-N 2.99Å; L523-Q527 WeakPolarHBondContact O-CB 3.33Å; L523-Q527 PolarHBondContact O-N 3.45Å
524	M	78.1	Confident	78.6	Confident	133 Å²	133	105.1 Å²	105.1	66%	0.655	50%	0.499	S	S	*	.	H	α-helix	trans	-59.5	-44.1	174	-87.3	-89	-79.7	0	0	112	E520 Q527 H528	E520-M524 PolarHBondContact O-N 3.42Å; M524-Q527 PolarHBondContact O-N 3.3Å; M524-H528 PolarHBondContact O-N 2.88Å
525	K	84	Confident	79.4	Confident	142 Å²	142	102.9 Å²	102.9	62%	0.617	49%	0.494	S	S	*	.	H	α-helix	trans	-64	-42.8	174.7	-74.4	172.7	-176.7	170.9	0	112	D521 H522 L523 H528 Q529	D521-K525 WeakPolarHBondContact O-CG 3.47Å; D521-K525 PolarHBondContact O-N 3.44Å; D521-K525 VanDerWaalsContact O-N 3.09Å; H522-K525 PolarHBondContact O-N 3.37Å; L523-K525 PolarHBondContact O-N 2.88Å; K525-H528 PolarHBondContact O-N 3.28Å; K525-Q529 WeakPolarHBondContact O-CG 3.32Å; K525-Q529 PolarHBondContact O-N 3.02Å
526	M	78.9	Confident	79.9	Confident	68 Å²	68	100.6 Å²	100.6	34%	0.335	49%	0.488	S	S	.	.	H	α-helix	trans	-65.4	-39.8	176.5	-73.5	-162.6	-54.2	0	0	112	H522 L523 Q529 L530	H522-M526 WeakPolarHBondContact O-CG 3.19Å; H522-M526 PolarHBondContact O-N 3.06Å; L523-M526 HydrophobicContact CD2-CE 3.63Å; L523-M526 HydrophobicContact CG-CE 4.42Å; L523-M526 PolarHBondContact O-N 2.99Å; M526-Q529 WeakPolarHBondContact O-CB 3.27Å; M526-Q529 PolarHBondContact O-N 2.95Å; M526-L530 WeakPolarHBondContact O-CB 3.39Å; M526-L530 PolarHBondContact O-N 3.37Å
527	Q	82.2	Confident	80.7	Confident	101 Å²	101	100.6 Å²	100.6	47%	0.472	49%	0.488	S	S	.	.	H	α-helix	trans	-61	-46.9	176.3	-173.3	66.5	22	0	0	110.8	L523 M524 Q529 L530 D531	L523-Q527 WeakPolarHBondContact O-CB 3.33Å; L523-Q527 PolarHBondContact O-N 3.45Å; M524-Q527 PolarHBondContact O-N 3.3Å; Q527-Q529 VanDerWaalsContact C-N 3.31Å; Q527-Q529 PolarHBondContact O-N 3.28Å; Q527-L530 PolarHBondContact O-N 3.47Å; Q527-L530 VanDerWaalsContact O-N 3.12Å; Q527-D531 PolarHBondContact O-N 3.46Å
528	H	84.5	Confident	81.6	Confident	135 Å²	135	100.7 Å²	100.7	63%	0.625	49%	0.492	S	S	*	.	H	α-helix	trans	-60.8	-39.5	175.5	-173.3	-67.1	0	0	0	112.2	M524 K525 T532	M524-H528 PolarHBondContact O-N 2.88Å; K525-H528 PolarHBondContact O-N 3.28Å; H528-T532 PolarHBondContact O-N 3.09Å; H528-T532 PolarHBondContact O-OG1 3.4Å
529	Q	83.6	Confident	81.9	Confident	88 Å²	88	101 Å²	101	41%	0.411	49%	0.49	S	S	.	.	H	α-helix	trans	-64.3	-42.2	173.8	-74.2	178.6	-13.8	0	0	111.6	K525 M526 Q527 T532 Y533	K525-Q529 WeakPolarHBondContact O-CG 3.32Å; K525-Q529 PolarHBondContact O-N 3.02Å; M526-Q529 WeakPolarHBondContact O-CB 3.27Å; M526-Q529 PolarHBondContact O-N 2.95Å; Q527-Q529 VanDerWaalsContact C-N 3.31Å; Q527-Q529 PolarHBondContact O-N 3.28Å; Q529-T532 WeakPolarHBondContact O-CB 3.46Å; Q529-T532 PolarHBondContact O-N 3.11Å; Q529-Y533 HydrophobicContact CB-CE2 4.32Å; Q529-Y533 WeakPolarHBondContact O-CD2 3.39Å; Q529-Y533 PolarHBondContact O-N 2.63Å
530	L	80	Confident	82.3	Confident	80 Å²	80	99 Å²	99	42%	0.419	48%	0.482	S	S	.	.	H	α-helix	trans	-66	-40	-179.7	-162.8	146.2	0	0	0	111.7	M526 Q527 T532 Y533 K534	M526-L530 WeakPolarHBondContact O-CB 3.39Å; M526-L530 PolarHBondContact O-N 3.37Å; Q527-L530 PolarHBondContact O-N 3.47Å; Q527-L530 VanDerWaalsContact O-N 3.12Å; L530-T532 VanDerWaalsContact C-N 3.34Å; L530-Y533 PolarHBondContact O-N 2.79Å; L530-K534 HydrophobicContact CD2-CD 3.91Å; L530-K534 HydrophobicContact CD2-CG 4.23Å; L530-K534 WeakPolarHBondContact O-CG 3.49Å; L530-K534 PolarHBondContact O-N 3.39Å
531	D	83.7	Confident	82.6	Confident	71 Å²	71	95.8 Å²	95.8	38%	0.38	47%	0.473	S	S	.	.	H	α-helix	trans	-66.1	-37.7	173.6	-70	-25.8	0	0	0	111.7	Q527 Y533 K534 T535	Q527-D531 PolarHBondContact O-N 3.46Å; D531-Y533 PolarHBondContact O-N 2.94Å; D531-K534 PolarHBondContact O-N 3.15Å; D531-T535 PolarHBondContact O-N 2.93Å; D531-T535 PolarHBondContact O-OG1 3.05Å
532	T	85.9	Confident	83	Confident	57 Å²	57	96.2 Å²	96.2	35%	0.35	48%	0.476	S	S	.	.	H	α-helix	trans	-61.8	-42.8	171.8	-54.6	0	0	0	0	111.3	H528 Q529 L530 T535 K536	H528-T532 PolarHBondContact O-N 3.09Å; H528-T532 PolarHBondContact O-OG1 3.4Å; Q529-T532 WeakPolarHBondContact O-CB 3.46Å; Q529-T532 PolarHBondContact O-N 3.11Å; L530-T532 VanDerWaalsContact C-N 3.34Å; T532-T535 PolarHBondContact O-N 2.71Å; T532-K536 WeakPolarHBondContact O-CG 3.47Å; T532-K536 PolarHBondContact O-N 3.2Å; T532-K536 VanDerWaalsContact O-N 3.14Å
533	Y	82.8	Confident	83.2	Confident	71 Å²	71	93.5 Å²	93.5	28%	0.278	46%	0.463	S	S	.	.	H	α-helix	trans	-67.8	-42.8	177.1	-74.3	-58.2	0	0	0	112.6	Q529 L530 D531 T535 K536 L537 L593 V596 F600	Q529-Y533 HydrophobicContact CB-CE2 4.32Å; Q529-Y533 WeakPolarHBondContact O-CD2 3.39Å; Q529-Y533 PolarHBondContact O-N 2.63Å; L530-Y533 PolarHBondContact O-N 2.79Å; D531-Y533 PolarHBondContact O-N 2.94Å; Y533-T535 VanDerWaalsContact C-N 3.26Å; Y533-T535 PolarHBondContact O-N 3.15Å; Y533-K536 PolarHBondContact O-N 2.91Å; Y533-L537 WeakPolarHBondContact O-CB 3.46Å; Y533-L537 PolarHBondContact O-N 3.4Å; Y533-L593 HydrophobicContact CD1-CD2 4.31Å; Y533-V596 HydrophobicContact CE1-CG1 3.8Å; Y533-V596 HydrophobicContact CE2-CG1 4.15Å; Y533-V596 VanDerWaalsContact CZ-CG1 3.5Å; Y533-V596 VanDerWaalsContact OH-CG1 3.29Å; Y533-V596 WeakPolarHBondContact OH-CG1 3.49Å; Y533-F600 AromaticContact CE2-CE2 3.94Å; Y533-F600 HydrophobicContact CE2-CE2 3.94Å; Y533-F600 HydrophobicContact CE2-CZ 4.38Å
534	K	82.7	Confident	83.4	Confident	124 Å²	124	92.6 Å²	92.6	54%	0.539	46%	0.458	S	S	.	.	H	α-helix	trans	-55.8	-43.1	174	-80.8	176.4	175.8	164.7	0	111.7	L530 D531 L537 K538	L530-K534 HydrophobicContact CD2-CD 3.91Å; L530-K534 HydrophobicContact CD2-CG 4.23Å; L530-K534 WeakPolarHBondContact O-CG 3.49Å; L530-K534 PolarHBondContact O-N 3.39Å; D531-K534 PolarHBondContact O-N 3.15Å; K534-L537 PolarHBondContact O-N 3.45Å; K534-K538 PolarHBondContact O-N 3.38Å
535	T	85.9	Confident	83.6	Confident	80 Å²	80	89.4 Å²	89.4	49%	0.491	45%	0.449	S	S	.	.	H	α-helix	trans	-62.3	-47.6	178.2	-49	0	0	0	0	111	D531 T532 Y533 L537 K538 E539	D531-T535 PolarHBondContact O-N 2.93Å; D531-T535 PolarHBondContact O-OG1 3.05Å; T532-T535 PolarHBondContact O-N 2.71Å; Y533-T535 VanDerWaalsContact C-N 3.26Å; Y533-T535 PolarHBondContact O-N 3.15Å; T535-L537 VanDerWaalsContact C-N 3.32Å; T535-L537 PolarHBondContact O-N 2.85Å; T535-K538 PolarHBondContact O-N 2.92Å; T535-E539 WeakPolarHBondContact O-CG 3.22Å; T535-E539 PolarHBondContact O-N 3.48Å
536	K	85.7	Confident	83.5	Confident	111 Å²	111	87.4 Å²	87.4	48%	0.483	45%	0.445	S	S	.	.	H	α-helix	trans	-62.7	-35.1	175.5	-71.8	178.2	178.5	176.9	0	113.5	T532 Y533 A540	T532-K536 WeakPolarHBondContact O-CG 3.47Å; T532-K536 PolarHBondContact O-N 3.2Å; T532-K536 VanDerWaalsContact O-N 3.14Å; Y533-K536 PolarHBondContact O-N 2.91Å; K536-A540 WeakPolarHBondContact O-CB 3.5Å; K536-A540 PolarHBondContact O-N 3.31Å
537	L	82.5	Confident	83.5	Confident	107 Å²	107	86 Å²	86	56%	0.56	44%	0.442	S	S	*	.	H	α-helix	trans	-72.3	-37.3	-179.8	-139.7	150.6	0	0	0	111.1	Y533 K534 T535 A540 S541	Y533-L537 WeakPolarHBondContact O-CB 3.46Å; Y533-L537 PolarHBondContact O-N 3.4Å; K534-L537 PolarHBondContact O-N 3.45Å; T535-L537 VanDerWaalsContact C-N 3.32Å; T535-L537 PolarHBondContact O-N 2.85Å; L537-A540 PolarHBondContact O-N 3.36Å; L537-S541 WeakPolarHBondContact O-CB 3.26Å; L537-S541 PolarHBondContact O-N 3.22Å
538	K	87.1	Confident	83.3	Confident	145 Å²	145	88.1 Å²	88.1	63%	0.63	45%	0.449	S	S	*	.	H	α-helix	trans	-61.7	-48.8	171.1	-171.3	177.8	179.6	-178.6	0	111.3	K534 T535 A540 S541 D542	K534-K538 PolarHBondContact O-N 3.38Å; T535-K538 PolarHBondContact O-N 2.92Å; K538-A540 VanDerWaalsContact C-N 3.33Å; K538-A540 PolarHBondContact O-N 2.87Å; K538-S541 WeakPolarHBondContact O-CB 3.3Å; K538-S541 PolarHBondContact O-N 2.91Å; K538-D542 VanDerWaalsContact O-CG 3.3Å; K538-D542 PolarHBondContact O-N 3.35Å
539	E	86.7	Confident	82.9	Confident	104 Å²	104	89.6 Å²	89.6	49%	0.486	45%	0.449	S	S	.	.	H	α-helix	trans	-56.5	-44.8	175.4	-70.7	172.2	-179.1	0	0	112.3	T535 D542 E543	T535-E539 WeakPolarHBondContact O-CG 3.22Å; T535-E539 PolarHBondContact O-N 3.48Å; E539-D542 PolarHBondContact O-N 3.48Å; E539-E543 WeakPolarHBondContact O-CG 3.45Å; E539-E543 PolarHBondContact O-N 2.75Å
540	A	83.1	Confident	82.6	Confident	33 Å²	33	88.7 Å²	88.7	27%	0.273	45%	0.447	S	S	.	.	H	α-helix	trans	-65.7	-39.3	177.7	0	0	0	0	0	112.7	K536 L537 K538 E543 I544	K536-A540 WeakPolarHBondContact O-CB 3.5Å; K536-A540 PolarHBondContact O-N 3.31Å; L537-A540 PolarHBondContact O-N 3.36Å; K538-A540 VanDerWaalsContact C-N 3.33Å; K538-A540 PolarHBondContact O-N 2.87Å; A540-E543 PolarHBondContact O-N 2.88Å; A540-I544 VanDerWaalsContact O-CG1 3.31Å; A540-I544 WeakPolarHBondContact O-CG1 3.48Å; A540-I544 PolarHBondContact O-N 3.27Å
541	S	83.4	Confident	82.1	Confident	59 Å²	59	89.8 Å²	89.8	41%	0.413	45%	0.453	S	S	.	.	H	α-helix	trans	-64	-42	175.6	-179.6	0	0	0	0	112	L537 K538 I544 S545	L537-S541 WeakPolarHBondContact O-CB 3.26Å; L537-S541 PolarHBondContact O-N 3.22Å; K538-S541 WeakPolarHBondContact O-CB 3.3Å; K538-S541 PolarHBondContact O-N 2.91Å; S541-I544 PolarHBondContact O-N 2.98Å; S541-S545 WeakPolarHBondContact O-CB 3.38Å; S541-S545 PolarHBondContact O-N 2.86Å; S541-S545 PolarHBondContact O-OG 3.34Å
542	D	85.7	Confident	81.4	Confident	93 Å²	93	89.7 Å²	89.7	50%	0.497	46%	0.457	S	S	.	.	H	α-helix	trans	-65.1	-40.5	177.3	-68.5	-18.7	0	0	0	110.9	K538 E539 S545 N546	K538-D542 VanDerWaalsContact O-CG 3.3Å; K538-D542 PolarHBondContact O-N 3.35Å; E539-D542 PolarHBondContact O-N 3.48Å; D542-S545 PolarHBondContact O-N 3.22Å; D542-N546 WeakPolarHBondContact O-CB 3.27Å; D542-N546 PolarHBondContact O-N 2.99Å
543	E	83.8	Confident	80.7	Confident	59 Å²	59	91.4 Å²	91.4	28%	0.276	46%	0.461	S	S	.	.	H	α-helix	trans	-63.9	-40.7	174	-77.1	-172.8	-176.3	0	0	113.4	E539 A540 N546 S547 N586	E539-E543 WeakPolarHBondContact O-CG 3.45Å; E539-E543 PolarHBondContact O-N 2.75Å; A540-E543 PolarHBondContact O-N 2.88Å; E543-N546 PolarHBondContact O-N 2.96Å; E543-S547 WeakPolarHBondContact O-CB 3.45Å; E543-S547 PolarHBondContact O-N 3.49Å; E543-S547 PolarHBondContact O-OG 3.02Å; E543-N586 PolarHBondContact OE2-ND2 3.12Å; E543-N586 PolarHBondContact OE2-OD1 2.75Å
544	I	82.2	Confident	79.7	Confident	84 Å²	84	95.1 Å²	95.1	43%	0.431	48%	0.476	S	S	.	.	H	α-helix	trans	-65.7	-43.6	176.1	-70.8	167.2	0	0	0	110.3	A540 S541 N546 S547 K548	A540-I544 VanDerWaalsContact O-CG1 3.31Å; A540-I544 WeakPolarHBondContact O-CG1 3.48Å; A540-I544 PolarHBondContact O-N 3.27Å; S541-I544 PolarHBondContact O-N 2.98Å; I544-N546 VanDerWaalsContact C-N 3.33Å; I544-N546 PolarHBondContact O-N 3.08Å; I544-S547 PolarHBondContact O-N 3.49Å; I544-K548 HydrophobicContact CG2-CD 4.45Å; I544-K548 PolarHBondContact O-N 3.46Å
545	S	80.3	Confident	78.3	Confident	65 Å²	65	93.2 Å²	93.2	46%	0.455	48%	0.483	S	S	.	.	H	α-helix	trans	-62.6	-42.5	178.6	-60.8	0	0	0	0	111.2	S541 D542 K548 R549	S541-S545 WeakPolarHBondContact O-CB 3.38Å; S541-S545 PolarHBondContact O-N 2.86Å; S541-S545 PolarHBondContact O-OG 3.34Å; D542-S545 PolarHBondContact O-N 3.22Å; S545-K548 PolarHBondContact O-N 2.86Å; S545-R549 WeakPolarHBondContact O-CB 3.25Å; S545-R549 PolarHBondContact O-N 3.44Å
546	N	83.1	Confident	76.9	Confident	100 Å²	100	95 Å²	95	54%	0.535	49%	0.494	S	S	.	.	H	α-helix	trans	-65	-39.2	175	-156.8	15.5	0	0	0	111.8	D542 E543 I544 R549 L550	D542-N546 WeakPolarHBondContact O-CB 3.27Å; D542-N546 PolarHBondContact O-N 2.99Å; E543-N546 PolarHBondContact O-N 2.96Å; I544-N546 VanDerWaalsContact C-N 3.33Å; I544-N546 PolarHBondContact O-N 3.08Å; N546-R549 PolarHBondContact O-N 3.06Å; N546-L550 WeakPolarHBondContact O-CG 3.29Å; N546-L550 PolarHBondContact O-N 3.22Å
547	S	78.3	Confident	75.4	Confident	39 Å²	39	98.2 Å²	98.2	27%	0.273	51%	0.508	S	S	.	.	H	α-helix	trans	-67	-40.7	176.3	-59.3	0	0	0	0	112.8	E543 I544 R549 L550 L551	E543-S547 WeakPolarHBondContact O-CB 3.45Å; E543-S547 PolarHBondContact O-N 3.49Å; E543-S547 PolarHBondContact O-OG 3.02Å; I544-S547 PolarHBondContact O-N 3.49Å; S547-R549 VanDerWaalsContact C-N 3.35Å; S547-L550 PolarHBondContact O-N 3.22Å; S547-L551 PolarHBondContact O-N 3.03Å
548	K	77.5	Confident	73.5	Confident	145 Å²	145	99.5 Å²	99.5	63%	0.63	51%	0.511	S	S	*	.	H	α-helix	trans	-62.5	-41.4	173.7	-79.1	-175.6	176.8	-178.8	0	111.7	I544 S545 L550 L551 S552	I544-K548 HydrophobicContact CG2-CD 4.45Å; I544-K548 PolarHBondContact O-N 3.46Å; S545-K548 PolarHBondContact O-N 2.86Å; K548-L550 VanDerWaalsContact C-N 3.34Å; K548-L551 PolarHBondContact O-N 3.35Å; K548-S552 PolarHBondContact O-N 2.86Å; K548-S552 PolarHBondContact O-OG 3.41Å
549	R	77.3	Confident	71	Confident	167 Å²	167	100.8 Å²	100.8	63%	0.63	53%	0.525	S	S	*	.	H	α-helix	trans	-63.7	-38.7	175.9	-176.4	178.7	167	167.6	-2.3	112.1	S545 N546 S547 S552 Q553	S545-R549 WeakPolarHBondContact O-CB 3.25Å; S545-R549 PolarHBondContact O-N 3.44Å; N546-R549 PolarHBondContact O-N 3.06Å; S547-R549 VanDerWaalsContact C-N 3.35Å; R549-S552 PolarHBondContact O-OG 2.92Å; R549-Q553 VanDerWaalsContact O-CG 3.3Å; R549-Q553 WeakPolarHBondContact O-CG 3.38Å; R549-Q553 PolarHBondContact O-N 3.29Å
550	L	76.8	Confident	68.6	Low	69 Å²	69	105.3 Å²	105.3	36%	0.361	54%	0.539	S	S	.	.	H	α-helix	trans	-67	-44.7	173.5	-72.6	168.2	0	0	0	111.3	N546 S547 K548 S552 Q553 Y554	N546-L550 WeakPolarHBondContact O-CG 3.29Å; N546-L550 PolarHBondContact O-N 3.22Å; S547-L550 PolarHBondContact O-N 3.22Å; K548-L550 VanDerWaalsContact C-N 3.34Å; L550-S552 PolarHBondContact O-N 3Å; L550-Q553 WeakPolarHBondContact O-CB 3.09Å; L550-Q553 PolarHBondContact O-N 3.46Å; L550-Q553 VanDerWaalsContact O-N 3.17Å; L550-Y554 HydrophobicContact CB-CE2 4.45Å; L550-Y554 WeakPolarHBondContact O-CD2 3.13Å; L550-Y554 PolarHBondContact O-N 2.85Å
551	L	70.1	Confident	66.2	Low	103 Å²	103	108.7 Å²	108.7	54%	0.539	56%	0.561	S	S	.	*	H	α-helix	trans	-62	-40.4	178.1	-79.5	167.1	0	0	0	112.9	S547 K548 Q553 Y554 A555	S547-L551 PolarHBondContact O-N 3.03Å; K548-L551 PolarHBondContact O-N 3.35Å; L551-Q553 VanDerWaalsContact C-N 3.29Å; L551-Q553 PolarHBondContact O-N 3.47Å; L551-Y554 PolarHBondContact O-N 2.87Å; L551-A555 WeakPolarHBondContact O-CB 3.23Å; L551-A555 PolarHBondContact O-N 3.28Å
552	S	69.5	Low	63.9	Low	68 Å²	68	111.3 Å²	111.3	48%	0.476	58%	0.576	S	S	.	*	H	α-helix	trans	-66.4	-31.6	175.7	62.2	0	0	0	0	112.6	K548 R549 L550 T556	K548-S552 PolarHBondContact O-N 2.86Å; K548-S552 PolarHBondContact O-OG 3.41Å; R549-S552 PolarHBondContact O-OG 2.92Å; L550-S552 PolarHBondContact O-N 3Å; S552-T556 WeakPolarHBondContact O-CG2 3.38Å; S552-T556 PolarHBondContact O-N 2.9Å; S552-T556 PolarHBondContact O-OG1 2.65Å
553	Q	70.4	Confident	61.6	Low	93 Å²	93	114.3 Å²	114.3	44%	0.435	59%	0.592	S	S	.	*	H	α-helix	trans	-69.2	-32.6	171.7	-73	176.2	-12.4	0	0	113	R549 L550 L551 T556	R549-Q553 VanDerWaalsContact O-CG 3.3Å; R549-Q553 WeakPolarHBondContact O-CG 3.38Å; R549-Q553 PolarHBondContact O-N 3.29Å; L550-Q553 WeakPolarHBondContact O-CB 3.09Å; L550-Q553 PolarHBondContact O-N 3.46Å; L550-Q553 VanDerWaalsContact O-N 3.17Å; L551-Q553 VanDerWaalsContact C-N 3.29Å; L551-Q553 PolarHBondContact O-N 3.47Å; Q553-T556 PolarHBondContact O-OG1 3.31Å
554	Y	61.7	Low	59.3	Low	150 Å²	150	121.2 Å²	121.2	59%	0.588	62%	0.622	S	S	*	*	H	α-helix	trans	-79.1	-40.7	175.4	-74.2	-69.3	0	0	0	112.4	L550 L551 T556 K557	L550-Y554 HydrophobicContact CB-CE2 4.45Å; L550-Y554 WeakPolarHBondContact O-CD2 3.13Å; L550-Y554 PolarHBondContact O-N 2.85Å; L551-Y554 PolarHBondContact O-N 2.87Å; Y554-T556 PolarHBondContact O-N 2.93Å; Y554-K557 PolarHBondContact O-N 3.36Å
555	A	54.3	Low	57.2	Low	83 Å²	83	123.9 Å²	123.9	69%	0.686	64%	0.641	S	S	*	*	H	α-helix	trans	-65.2	-24.6	179.9	0	0	0	0	0	113.2	L551 K557	L551-A555 WeakPolarHBondContact O-CB 3.23Å; L551-A555 PolarHBondContact O-N 3.28Å; A555-K557 VanDerWaalsContact C-N 3.31Å
556	T	55.8	Low	55.2	Low	117 Å²	117	128.8 Å²	128.8	72%	0.718	66%	0.663	S	S	*	*	T	Hydrogen-bonded Turn	trans	-84.1	-2.6	174.7	45.6	0	0	0	0	113.6	S552 Q553 Y554	S552-T556 WeakPolarHBondContact O-CG2 3.38Å; S552-T556 PolarHBondContact O-N 2.9Å; S552-T556 PolarHBondContact O-OG1 2.65Å; Q553-T556 PolarHBondContact O-OG1 3.31Å; Y554-T556 PolarHBondContact O-N 2.93Å
557	K	54.2	Low	53.1	Low	180 Å²	180	132.6 Å²	132.6	78%	0.783	68%	0.677	S	S	*	*	T	Hydrogen-bonded Turn	trans	-122.2	-4.5	-171.8	-86.6	-172.5	174.7	-177.1	0	116.8	Y554 A555	Y554-K557 PolarHBondContact O-N 3.36Å; A555-K557 VanDerWaalsContact C-N 3.31Å
558	Q	42.5	Very low	51.1	Low	134 Å²	134	139 Å²	139	63%	0.626	71%	0.707	S	S	*	*			trans	-141.3	116.1	-179.1	-79.3	-176.4	-27.7	0	0	114	Y560	Q558-Y560 HydrophobicContact CB-CD2 4.42Å; Q558-Y560 PolarHBondContact O-N 3.37Å
559	D	35	Very low	49.1	Very low	172 Å²	172	139.2 Å²	139.2	92%	0.92	72%	0.715	S	S	*	*			trans	-48	113.5	151.8	-70.2	-48.9	0	0	0	109.6
560	Y	36.1	Very low	47.2	Very low	198 Å²	198	137.5 Å²	137.5	78%	0.776	72%	0.719	S	S	*	*			trans	-126.9	106.7	168.3	-118.4	-90.2	0	0	0	109.9	Q558	Q558-Y560 HydrophobicContact CB-CD2 4.42Å; Q558-Y560 PolarHBondContact O-N 3.37Å
561	S	33.2	Very low	45.4	Very low	105 Å²	105	142.1 Å²	142.1	73%	0.734	74%	0.738	S	S	*	*			trans	-66.6	128.9	170.9	-170.9	0	0	0	0	109.8	N563	S561-N563 PolarHBondContact O-N 3.02Å
562	P	35	Very low	43.7	Very low	113 Å²	113	146.4 Å²	146.4	73%	0.734	75%	0.752	S	S	*	*	S	Bend	trans	-88.9	95.6	178.9	32.8	-26.9	0	0	0	108.6
563	N	36.5	Very low	42.1	Very low	156 Å²	156	152.1 Å²	152.1	83%	0.834	77%	0.774	S	S	*	*			trans	178.2	98.8	159	-89.9	-23.7	0	0	0	108.7	S561	S561-N563 PolarHBondContact O-N 3.02Å
564	K	36.2	Very low	40.4	Very low	205 Å²	205	155.4 Å²	155.4	89%	0.891	80%	0.795	S	S	*	*			trans	146	74.6	162.7	-86.3	176.3	179.1	-172.6	0	110.3
565	V	38.3	Very low	39.1	Very low	139 Å²	139	153.9 Å²	153.9	84%	0.842	81%	0.806	S	S	*	*			trans	-145.5	62.4	160.7	-165.9	0	0	0	0	109.1
566	D	38.4	Very low	38.1	Very low	169 Å²	169	153.8 Å²	153.8	90%	0.904	80%	0.8	S	S	*	*	S	Bend	trans	-120.7	2.2	164.6	-87.2	-34.5	0	0	0	112.9
567	E	37.5	Very low	37.4	Very low	180 Å²	180	152.2 Å²	152.2	84%	0.841	79%	0.794	S	S	*	*			trans	-141.5	97.4	178.9	-70.8	-179.5	166.9	0	0	109.1
568	L	36.1	Very low	36.6	Very low	172 Å²	172	149.7 Å²	149.7	90%	0.901	79%	0.788	S	S	*	*			trans	-168.4	68	155.6	-100.3	150.4	0	0	0	108.3
569	N	36.6	Very low	36.6	Very low	150 Å²	150	147.8 Å²	147.8	80%	0.802	78%	0.782	S	S	*	*			trans	-70.5	143.3	151	-85.2	-26.5	0	0	0	108.7
570	D	37.9	Very low	37	Very low	132 Å²	132	147.9 Å²	147.9	71%	0.706	78%	0.775	S	S	*	*	S	Bend	trans	71.8	112.6	156.5	-64.3	-26.8	0	0	0	120.9
571	H	37.7	Very low	37.4	Very low	165 Å²	165	144 Å²	144	76%	0.764	77%	0.766	S	S	*	*			trans	91.7	116.4	144.4	-64.7	-50	0	0	0	121.2
572	K	35.4	Very low	38	Very low	193 Å²	193	144.1 Å²	144.1	84%	0.839	75%	0.753	S	S	*	*			trans	61.4	101.4	144.1	-73.9	177.8	174.7	174.4	0	116.4
573	M	35.1	Very low	38.4	Very low	188 Å²	188	146.2 Å²	146.2	93%	0.926	75%	0.747	S	S	*	*				-165.6	133.7	119.4	-94	-107.3	178.8	0	0	110.5	S575	M573-S575 PolarHBondContact O-N 2.99Å
574	N	34.6	Very low	39	Very low	163 Å²	163	147 Å²	147	87%	0.872	74%	0.743	S	S	*	*			trans	-78.2	109.4	-173.4	-67.4	-41	0	0	0	110.6
575	S	34.5	Very low	39.6	Very low	117 Å²	117	140 Å²	140	82%	0.818	72%	0.719	S	S	*	*	S	Bend	trans	-178.5	54.7	150.8	59.5	0	0	0	0	112.8	M573	M573-S575 PolarHBondContact O-N 2.99Å
576	S	34.1	Very low	40.1	Very low	81 Å²	81	135.1 Å²	135.1	57%	0.566	69%	0.688	S	S	*	*			trans	-173.5	46.2	152.6	66.1	0	0	0	0	110.7	L578 N579	S576-L578 PolarHBondContact O-N 2.98Å; S576-N579 PolarHBondContact O-N 3.45Å
577	S	39.5	Very low	40.9	Very low	84 Å²	84	132.2 Å²	132.2	59%	0.587	67%	0.672	S	S	*	*	H	α-helix	trans	-66.9	-22.3	176.9	50.2	0	0	0	0	112.3	N579 I581	S577-N579 PolarHBondContact O-N 3.03Å; S577-I581 WeakPolarHBondContact O-CB 3.4Å; S577-I581 VanDerWaalsContact O-CD1 3.25Å; S577-I581 WeakPolarHBondContact O-CD1 3.42Å; S577-I581 WeakPolarHBondContact O-CG1 3.41Å; S577-I581 PolarHBondContact O-N 3.09Å
578	L	39.3	Very low	42	Very low	127 Å²	127	129.8 Å²	129.8	67%	0.665	66%	0.661	S	S	*	*	H	α-helix	trans	-69.1	-32.5	177.6	-98	98.8	0	0	0	114.3	S576 K582	S576-L578 PolarHBondContact O-N 2.98Å; L578-K582 WeakPolarHBondContact O-CB 3.36Å; L578-K582 PolarHBondContact O-N 3.35Å; L578-K582 VanDerWaalsContact O-N 3.14Å
579	N	41.6	Very low	42.9	Very low	95 Å²	95	126.3 Å²	126.3	51%	0.508	64%	0.638	S	S	.	*	H	α-helix	trans	-86.5	-35.6	-173.1	-76.4	-11.7	0	0	0	113.4	S576 S577 W583	S576-N579 PolarHBondContact O-N 3.45Å; S577-N579 PolarHBondContact O-N 3.03Å; N579-W583 VanDerWaalsContact O-CD1 3.29Å; N579-W583 PolarHBondContact O-N 3.04Å; N579-W583 VanDerWaalsContact O-N 3.09Å
580	K	43	Very low	43.7	Very low	174 Å²	174	124.3 Å²	124.3	76%	0.757	63%	0.627	S	S	*	*	H	α-helix	trans	-72.3	-32.7	173.2	-95.3	-179.2	176.1	176.5	0	112.7	K584	K580-K584 PolarHBondContact O-N 3.34Å; K580-K584 VanDerWaalsContact O-N 3.09Å
581	I	44.6	Very low	44.9	Very low	116 Å²	116	121.2 Å²	121.2	60%	0.595	61%	0.613	S	S	*	*	H	α-helix	trans	-71.9	-40.2	175.6	-64	172.5	0	0	0	110.6	S577 K584 S585	S577-I581 WeakPolarHBondContact O-CB 3.4Å; S577-I581 VanDerWaalsContact O-CD1 3.25Å; S577-I581 WeakPolarHBondContact O-CD1 3.42Å; S577-I581 WeakPolarHBondContact O-CG1 3.41Å; S577-I581 PolarHBondContact O-N 3.09Å; I581-K584 PolarHBondContact O-N 2.74Å; I581-S585 VanDerWaalsContact O-CB 3.27Å; I581-S585 WeakPolarHBondContact O-CB 2.96Å; I581-S585 PolarHBondContact O-N 3.2Å
582	K	45.7	Very low	46	Very low	108 Å²	108	117.7 Å²	117.7	47%	0.47	60%	0.6	S	S	.	*	H	α-helix	trans	-61.4	-42.9	172.3	-91.3	-173.7	170.4	-173.7	0	112.7	L578 S585 N586	L578-K582 WeakPolarHBondContact O-CB 3.36Å; L578-K582 PolarHBondContact O-N 3.35Å; L578-K582 VanDerWaalsContact O-N 3.14Å; K582-S585 PolarHBondContact O-N 3.16Å; K582-N586 WeakPolarHBondContact O-CB 3.29Å; K582-N586 PolarHBondContact O-N 3.38Å
583	W	43.3	Very low	47	Very low	157 Å²	157	111 Å²	111	60%	0.595	57%	0.573	S	S	*	*	H	α-helix	trans	-66.2	-42.5	178.4	-91	73.9	0	0	0	113.1	N579 N586 L587	N579-W583 VanDerWaalsContact O-CD1 3.29Å; N579-W583 PolarHBondContact O-N 3.04Å; N579-W583 VanDerWaalsContact O-N 3.09Å; W583-N586 PolarHBondContact O-N 2.72Å; W583-L587 PolarHBondContact O-N 3.18Å
584	K	50.5	Low	48	Very low	173 Å²	173	108.7 Å²	108.7	75%	0.752	56%	0.557	S	S	*	*	H	α-helix	trans	-64.7	-40.2	173.4	-103.4	-175.2	174.8	-177.1	0	112.2	K580 I581 L587 H588	K580-K584 PolarHBondContact O-N 3.34Å; K580-K584 VanDerWaalsContact O-N 3.09Å; I581-K584 PolarHBondContact O-N 2.74Å; K584-L587 PolarHBondContact O-N 2.76Å; K584-H588 WeakPolarHBondContact O-CB 3.43Å; K584-H588 PolarHBondContact O-N 3.03Å
585	S	47.6	Very low	49.1	Very low	56 Å²	56	104.7 Å²	104.7	39%	0.392	54%	0.536	S	S	.	.	H	α-helix	trans	-63.5	-41	175.9	-171.9	0	0	0	0	111.6	I581 K582 H588 K589	I581-S585 VanDerWaalsContact O-CB 3.27Å; I581-S585 WeakPolarHBondContact O-CB 2.96Å; I581-S585 PolarHBondContact O-N 3.2Å; K582-S585 PolarHBondContact O-N 3.16Å; S585-H588 PolarHBondContact O-N 2.93Å; S585-K589 WeakPolarHBondContact O-CB 3.32Å; S585-K589 WeakPolarHBondContact O-CG 3.5Å; S585-K589 PolarHBondContact O-N 3.25Å
586	N	49.5	Very low	50	Low	37 Å²	37	100.9 Å²	100.9	20%	0.198	51%	0.508	C	S	.	.	H	α-helix	trans	-72.5	-34.9	178.5	-75.4	-8.4	0	0	0	113	E543 K582 W583 K589 L590	E543-N586 PolarHBondContact OE2-ND2 3.12Å; E543-N586 PolarHBondContact OE2-OD1 2.75Å; K582-N586 WeakPolarHBondContact O-CB 3.29Å; K582-N586 PolarHBondContact O-N 3.38Å; W583-N586 PolarHBondContact O-N 2.72Å; N586-K589 PolarHBondContact O-N 3.25Å; N586-L590 WeakPolarHBondContact O-CB 3.37Å; N586-L590 PolarHBondContact O-N 3.16Å
587	L	54.9	Low	50.7	Low	108 Å²	108	100.1 Å²	100.1	57%	0.565	51%	0.506	S	S	*	.	H	α-helix	trans	-64.8	-41.2	170.1	-118	111.9	0	0	0	111.6	W583 K584 L590 T591	W583-L587 PolarHBondContact O-N 3.18Å; K584-L587 PolarHBondContact O-N 2.76Å; L587-L590 PolarHBondContact O-N 3.01Å; L587-T591 WeakPolarHBondContact O-CB 3.49Å; L587-T591 PolarHBondContact O-N 3.44Å; L587-T591 PolarHBondContact O-OG1 2.89Å
588	H	59.8	Low	51.1	Low	129 Å²	129	101.6 Å²	101.6	60%	0.597	50%	0.504	S	S	*	.	H	α-helix	trans	-66.6	-40	176.6	-160.4	68.7	0	0	0	111.6	K584 S585 T591 L592	K584-H588 WeakPolarHBondContact O-CB 3.43Å; K584-H588 PolarHBondContact O-N 3.03Å; S585-H588 PolarHBondContact O-N 2.93Å; H588-T591 PolarHBondContact O-N 3.09Å; H588-L592 WeakPolarHBondContact O-CB 3.49Å; H588-L592 PolarHBondContact O-N 3.43Å
589	K	54.9	Low	51.5	Low	99 Å²	99	100.3 Å²	100.3	43%	0.43	50%	0.498	S	S	.	.	H	α-helix	trans	-62.6	-42.3	172	-78.7	-179	179.5	-179.8	0	112.5	S585 N586 L592 L593	S585-K589 WeakPolarHBondContact O-CB 3.32Å; S585-K589 WeakPolarHBondContact O-CG 3.5Å; S585-K589 PolarHBondContact O-N 3.25Å; N586-K589 PolarHBondContact O-N 3.25Å; K589-L592 PolarHBondContact O-N 2.84Å; K589-L593 WeakPolarHBondContact O-CB 3.42Å; K589-L593 PolarHBondContact O-N 2.81Å
590	L	53.5	Low	51.7	Low	108 Å²	108	100.5 Å²	100.5	57%	0.565	49%	0.494	S	S	*	.	H	α-helix	trans	-64.6	-38.9	175.2	-89.2	159.4	0	0	0	112.1	N586 L587 L593 K594	N586-L590 WeakPolarHBondContact O-CB 3.37Å; N586-L590 PolarHBondContact O-N 3.16Å; L587-L590 PolarHBondContact O-N 3.01Å; L590-L593 PolarHBondContact O-N 3.28Å; L590-K594 WeakPolarHBondContact O-CB 3.47Å; L590-K594 PolarHBondContact O-N 3.38Å
591	T	63.8	Low	51.5	Low	68 Å²	68	94 Å²	94	42%	0.417	48%	0.477	S	S	.	.	H	α-helix	trans	-68.1	-41.3	176.2	-47.8	0	0	0	0	110.9	L587 H588 K594 N595	L587-T591 WeakPolarHBondContact O-CB 3.49Å; L587-T591 PolarHBondContact O-N 3.44Å; L587-T591 PolarHBondContact O-OG1 2.89Å; H588-T591 PolarHBondContact O-N 3.09Å; T591-K594 PolarHBondContact O-N 3.02Å; T591-N595 WeakPolarHBondContact O-CB 3.44Å; T591-N595 VanDerWaalsContact O-CG 3.29Å; T591-N595 PolarHBondContact O-N 2.96Å
592	L	61	Low	51.4	Low	91 Å²	91	90.9 Å²	90.9	48%	0.476	47%	0.468	S	S	.	.	H	α-helix	trans	-61.9	-43.9	172.4	-90.2	157.5	0	0	0	112.2	H588 K589 K594 N595 V596	H588-L592 WeakPolarHBondContact O-CB 3.49Å; H588-L592 PolarHBondContact O-N 3.43Å; K589-L592 PolarHBondContact O-N 2.84Å; L592-K594 VanDerWaalsContact C-N 3.34Å; L592-K594 PolarHBondContact O-N 3.19Å; L592-N595 PolarHBondContact O-N 3.32Å; L592-V596 WeakPolarHBondContact O-CB 3.32Å; L592-V596 VanDerWaalsContact O-CG2 3.24Å; L592-V596 WeakPolarHBondContact O-CG2 3.44Å; L592-V596 PolarHBondContact O-N 3.16Å
593	L	55.5	Low	51.1	Low	53 Å²	53	91.8 Å²	91.8	28%	0.277	48%	0.478	S	S	.	.	H	α-helix	trans	-63.7	-38.8	175.8	-84.5	161.2	0	0	0	112	Y533 K589 L590 V596 A597	Y533-L593 HydrophobicContact CD1-CD2 4.31Å; K589-L593 WeakPolarHBondContact O-CB 3.42Å; K589-L593 PolarHBondContact O-N 2.81Å; L590-L593 PolarHBondContact O-N 3.28Å; L593-V596 PolarHBondContact O-N 2.88Å; L593-A597 WeakPolarHBondContact O-CB 3.44Å; L593-A597 PolarHBondContact O-N 3.47Å
594	K	56.2	Low	50.9	Low	138 Å²	138	89.4 Å²	89.4	60%	0.6	48%	0.481	S	S	*	.	H	α-helix	trans	-65.6	-42.1	175.2	-164.9	177.9	-178.5	-177.6	0	111.6	L590 T591 L592 A597 Q598	L590-K594 WeakPolarHBondContact O-CB 3.47Å; L590-K594 PolarHBondContact O-N 3.38Å; T591-K594 PolarHBondContact O-N 3.02Å; L592-K594 VanDerWaalsContact C-N 3.34Å; L592-K594 PolarHBondContact O-N 3.19Å; K594-A597 PolarHBondContact O-N 3.38Å; K594-Q598 WeakPolarHBondContact O-CB 3.48Å; K594-Q598 WeakPolarHBondContact O-CG 3.42Å; K594-Q598 PolarHBondContact O-N 2.93Å
595	N	57.4	Low	50.4	Low	79 Å²	79	89.2 Å²	89.2	42%	0.422	48%	0.483	S	S	.	.	H	α-helix	trans	-68.1	-37.6	176.1	-70.7	-6.7	0	0	0	112.1	T591 L592 Q598 N599	T591-N595 WeakPolarHBondContact O-CB 3.44Å; T591-N595 VanDerWaalsContact O-CG 3.29Å; T591-N595 PolarHBondContact O-N 2.96Å; L592-N595 PolarHBondContact O-N 3.32Å; N595-Q598 PolarHBondContact O-N 2.89Å; N595-N599 WeakPolarHBondContact O-CB 3.33Å; N595-N599 PolarHBondContact O-N 3.23Å; N595-N599 PolarHBondContact O-ND2 3.35Å
596	V	54.1	Low	49.8	Very low	37 Å²	37	93.7 Å²	93.7	22%	0.224	50%	0.502	C	S	.	.	H	α-helix	trans	-64.8	-45.2	173.3	167.7	0	0	0	0	110.7	Y533 L592 L593 Q598 N599 F600	Y533-V596 HydrophobicContact CE1-CG1 3.8Å; Y533-V596 HydrophobicContact CE2-CG1 4.15Å; Y533-V596 VanDerWaalsContact CZ-CG1 3.5Å; Y533-V596 VanDerWaalsContact OH-CG1 3.29Å; Y533-V596 WeakPolarHBondContact OH-CG1 3.49Å; L592-V596 WeakPolarHBondContact O-CB 3.32Å; L592-V596 VanDerWaalsContact O-CG2 3.24Å; L592-V596 WeakPolarHBondContact O-CG2 3.44Å; L592-V596 PolarHBondContact O-N 3.16Å; L593-V596 PolarHBondContact O-N 2.88Å; V596-Q598 VanDerWaalsContact C-N 3.33Å; V596-Q598 PolarHBondContact O-N 2.84Å; V596-N599 PolarHBondContact O-N 2.84Å; V596-F600 HydrophobicContact CG1-CD2 3.78Å; V596-F600 HydrophobicContact CG1-CE2 4.01Å; V596-F600 WeakPolarHBondContact O-CD2 3.24Å; V596-F600 PolarHBondContact O-N 2.88Å
597	A	49.1	Very low	48.9	Very low	65 Å²	65	96.3 Å²	96.3	54%	0.537	52%	0.524	S	S	.	.	H	α-helix	trans	-62.7	-39	177.1	0	0	0	0	0	112.1	L593 K594 G601	L593-A597 WeakPolarHBondContact O-CB 3.44Å; L593-A597 PolarHBondContact O-N 3.47Å; K594-A597 PolarHBondContact O-N 3.38Å; A597-G601 PolarHBondContact O-N 3.28Å; A597-G601 VanDerWaalsContact O-N 3.09Å
598	Q	48.6	Very low	47.7	Very low	115 Å²	115	98 Å²	98	54%	0.537	53%	0.533	S	S	.	.	H	α-helix	trans	-67.9	-38.9	174.1	-77	-179.7	-32.2	0	0	112.5	K594 N595 V596 G601 A602	K594-Q598 WeakPolarHBondContact O-CB 3.48Å; K594-Q598 WeakPolarHBondContact O-CG 3.42Å; K594-Q598 PolarHBondContact O-N 2.93Å; N595-Q598 PolarHBondContact O-N 2.89Å; V596-Q598 VanDerWaalsContact C-N 3.33Å; V596-Q598 PolarHBondContact O-N 2.84Å; Q598-G601 PolarHBondContact O-N 3.3Å; Q598-A602 WeakPolarHBondContact O-CB 3.31Å; Q598-A602 PolarHBondContact O-N 3.48Å
599	N	47.6	Very low	46.4	Very low	101 Å²	101	96 Å²	96	54%	0.54	53%	0.532	S	S	.	.	H	α-helix	trans	-71.8	-30.6	177	-72.6	-18.4	0	0	0	113	N595 V596 N603	N595-N599 WeakPolarHBondContact O-CB 3.33Å; N595-N599 PolarHBondContact O-N 3.23Å; N595-N599 PolarHBondContact O-ND2 3.35Å; V596-N599 PolarHBondContact O-N 2.84Å; N599-N603 WeakPolarHBondContact O-CB 3.3Å; N599-N603 PolarHBondContact O-N 2.96Å; N599-N603 VanDerWaalsContact O-N 3.17Å
600	F	44.2	Very low	45.4	Very low	98 Å²	98	98.7 Å²	98.7	43%	0.43	55%	0.55	S	S	.	*	H	α-helix	trans	-70.7	-34.2	171.4	-96.1	-84.2	0	0	0	112.3	Y533 V596 T604	Y533-F600 AromaticContact CE2-CE2 3.94Å; Y533-F600 HydrophobicContact CE2-CE2 3.94Å; Y533-F600 HydrophobicContact CE2-CZ 4.38Å; V596-F600 HydrophobicContact CG1-CD2 3.78Å; V596-F600 HydrophobicContact CG1-CE2 4.01Å; V596-F600 WeakPolarHBondContact O-CD2 3.24Å; V596-F600 PolarHBondContact O-N 2.88Å; F600-T604 PolarHBondContact O-OG1 3.04Å
601	G	40.6	Very low	44.5	Very low	38 Å²	38	103.1 Å²	103.1	39%	0.392	57%	0.565	S	S	.	*	H	α-helix	trans	-71.2	-35.6	172.2	0	0	0	0	0	113.7	A597 Q598 T604	A597-G601 PolarHBondContact O-N 3.28Å; A597-G601 VanDerWaalsContact O-N 3.09Å; Q598-G601 PolarHBondContact O-N 3.3Å; G601-T604 PolarHBondContact O-OG1 2.86Å
602	A	40.8	Very low	43	Very low	50 Å²	50	109.2 Å²	109.2	41%	0.413	59%	0.589	S	S	.	*	H	α-helix	trans	-80.1	-26.5	-178.1	0	0	0	0	0	114.1	Q598 T604	Q598-A602 WeakPolarHBondContact O-CB 3.31Å; Q598-A602 PolarHBondContact O-N 3.48Å; A602-T604 VanDerWaalsContact C-N 3.32Å
603	N	40	Very low	41.5	Very low	128 Å²	128	110.7 Å²	110.7	68%	0.684	61%	0.607	S	S	*	*	T	Hydrogen-bonded Turn	trans	-82	-8	178.8	-78.7	-16.6	0	0	0	114.1	N599	N599-N603 WeakPolarHBondContact O-CB 3.3Å; N599-N603 PolarHBondContact O-N 2.96Å; N599-N603 VanDerWaalsContact O-N 3.17Å
604	T	39.9	Very low	40.3	Very low	107 Å²	107	116.6 Å²	116.6	66%	0.656	63%	0.633	S	S	*	*	T	Hydrogen-bonded Turn	trans	-89.9	-11.1	174.9	34.5	0	0	0	0	113.2	F600 G601 A602	F600-T604 PolarHBondContact O-OG1 3.04Å; G601-T604 PolarHBondContact O-OG1 2.86Å; A602-T604 VanDerWaalsContact C-N 3.32Å
605	E	38.6	Very low	39.1	Very low	169 Å²	169	116.6 Å²	116.6	79%	0.79	64%	0.644	S	S	*	*	S	Bend	trans	-100.4	-2.5	179.8	-70.5	-175	160.2	0	0	114.6
606	N	35	Very low	37.7	Very low	149 Å²	149	121.1 Å²	121.1	80%	0.797	67%	0.667	S	S	*	*	S	Bend	trans	-122.3	8.6	-175	-91.2	-29	0	0	0	116.8	N608	N606-N608 PolarHBondContact O-N 2.91Å
607	S	31.5	Very low	36.6	Very low	93 Å²	93	127.8 Å²	127.8	65%	0.65	70%	0.695	S	S	*	*			trans	-93.7	80.8	175	59.4	0	0	0	0	111.6	P609	S607-P609 WeakPolarHBondContact O-CD 3.38Å
608	N	30.8	Very low	35.8	Very low	142 Å²	142	130.5 Å²	130.5	76%	0.759	71%	0.705	S	S	*	*			trans	-89.8	104.9	169	-143.3	-8.4	0	0	0	108.2	N606 L610	N606-N608 PolarHBondContact O-N 2.91Å; N608-L610 PolarHBondContact O-N 2.86Å
609	P	32.1	Very low	34.9	Very low	89 Å²	89	133 Å²	133	58%	0.578	72%	0.717	S	S	*	*	T	Hydrogen-bonded Turn	trans	-81.7	19.6	-166.8	-9.3	27.6	0	0	0	114.9	R515 S607	R515-P609 VanDerWaalsContact NH2-CB 3.35Å; S607-P609 WeakPolarHBondContact O-CD 3.38Å
610	L	33.7	Very low	34.2	Very low	155 Å²	155	135.1 Å²	135.1	81%	0.812	73%	0.728	S	S	*	*	T	Hydrogen-bonded Turn	trans	-114.1	12.1	-164.9	-95.7	154.8	0	0	0	115.3	N608	N608-L610 PolarHBondContact O-N 2.86Å
611	K	35	Very low	33.7	Very low	201 Å²	201	142.1 Å²	142.1	87%	0.874	77%	0.77	S	S	*	*	S	Bend	trans	-135.9	14.1	-177.2	-81.9	-170.1	175.9	-178.8	0	117.6
612	Q	30.9	Very low	33.3	Very low	195 Å²	195	147.3 Å²	147.3	91%	0.911	79%	0.789	S	S	*	*			trans	-130.3	74.6	178.1	-76.2	-179.6	-13.6	0	0	112
613	S	30.3	Very low	32.9	Very low	123 Å²	123	152.4 Å²	152.4	86%	0.86	81%	0.809	S	S	*	*	S	Bend	trans	-154	26.1	159.5	67.9	0	0	0	0	112.4
614	Q	31	Very low	32.5	Very low	177 Å²	177	153.8 Å²	153.8	83%	0.827	82%	0.816	S	S	*	*	S	Bend	trans	-121.8	140.2	163.2	-76.2	-179.9	-22	0	0	106
615	V	29.7	Very low	32.1	Very low	137 Å²	137	156.5 Å²	156.5	83%	0.83	83%	0.825	S	S	*	*			trans	83.8	81.4	-174.5	-161.8	0	0	0	0	113.3
616	I	29.3	Very low	31.7	Very low	175 Å²	175	155.8 Å²	155.8	90%	0.897	83%	0.827	S	S	*	*				-161.9	84.9	121.6	-78.5	142	0	0	0	104.6
617	Q	30.6	Very low	31.5	Very low	177 Å²	177	156.2 Å²	156.2	83%	0.827	83%	0.829	S	S	*	*			trans	-137.1	145.6	154.1	-103.3	-174.5	-6.5	0	0	105.7
618	T	31.7	Very low	31.5	Very low	121 Å²	121	160.7 Å²	160.7	74%	0.742	84%	0.842	S	S	*	*			trans	79.1	113.6	166.5	58	0	0	0	0	119.1
619	E	30.4	Very low	31.5	Very low	168 Å²	168	162.2 Å²	162.2	79%	0.785	85%	0.848	S	S	*	*			trans	111.7	98.8	132.5	-76.2	167.9	179.7	0	0	118.9
620	N	31.5	Very low	31.5	Very low	146 Å²	146	168.3 Å²	168.3	78%	0.781	87%	0.871	S	S	*	*				47.3	100.8	125	-61.6	-14.7	0	0	0	118.6
621	D	33.8	Very low	31.3	Very low	244 Å²	244	169.5 Å²	169.5	100%	1.305	88%	0.876	S	S	*	*				-157.8	0	104.9	-94.3	-20	0	0	0	110.4

Retrieved 621 of 621 residues in 140.6 ms (Link to these results)

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