A0A5K4EJW2_SCHMA Loading...

Putative divalent metal transporter DMT1B

AlphaFold DB , UniProt , Accession A0A5K4EJW2, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 594 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	33.4	Very low	33.1	Very low	241 Å²	241	158.8 Å²	158.8	100%	1.187	85%	0.849	S	S	*	*				0	104.5	0	-74.3	173.5	171.8	0	0	106.6
2	H	34.5	Very low	33.3	Very low	174 Å²	174	152 Å²	152	81%	0.806	85%	0.845	S	S	*	*			cis	-146.2	124.4	-1.1	-104.8	-93.9	0	0	0	102.7
3	V	32.1	Very low	33.1	Very low	125 Å²	125	158.9 Å²	158.9	76%	0.758	85%	0.85	S	S	*	*				53.3	121	81.4	-173.5	0	0	0	0	110.8
4	C	32.3	Very low	33.3	Very low	124 Å²	124	157.4 Å²	157.4	84%	0.838	85%	0.849	S	S	*	*			cis	-168.5	168.6	48.3	-130.5	0	0	0	0	113.3
5	L	30.3	Very low	33.2	Very low	151 Å²	151	154.3 Å²	154.3	79%	0.791	84%	0.841	S	S	*	*			trans	-91.6	174	175.8	-75.4	156.1	0	0	0	113.2
6	D	34.6	Very low	33.2	Very low	161 Å²	161	154.8 Å²	154.8	86%	0.861	84%	0.842	S	S	*	*			trans	107	133.1	148.7	-61.3	-30.4	0	0	0	120.7
7	G	34	Very low	33.2	Very low	70 Å²	70	154.4 Å²	154.4	72%	0.722	84%	0.838	S	S	*	*			trans	134.8	91.8	141.2	0	0	0	0	0	119.5
8	E	35.1	Very low	33	Very low	181 Å²	181	151.8 Å²	151.8	85%	0.846	83%	0.833	S	S	*	*			trans	43.8	118.3	135.9	-73.5	-179.2	151.1	0	0	122.5
9	E	31.5	Very low	32.8	Very low	170 Å²	170	151.7 Å²	151.7	79%	0.794	83%	0.831	S	S	*	*				68.3	106.2	99.7	-88.1	-168.8	175.5	0	0	117.1
10	N	34.8	Very low	32.7	Very low	158 Å²	158	151.4 Å²	151.4	85%	0.845	82%	0.824	S	S	*	*				-176.4	146.8	116.8	-110.6	-43.9	0	0	0	114.5
11	E	31.9	Very low	32.6	Very low	192 Å²	192	149.2 Å²	149.2	90%	0.897	82%	0.82	S	S	*	*			trans	-65.9	149.8	-177.1	-67.3	178.3	114	0	0	115.2
12	G	35	Very low	32.4	Very low	77 Å²	77	147.1 Å²	147.1	79%	0.794	80%	0.799	S	S	*	*			trans	-177.9	97.1	166.5	0	0	0	0	0	113.8
13	R	31.3	Very low	32.1	Very low	242 Å²	242	145.3 Å²	145.3	91%	0.913	80%	0.8	S	S	*	*			trans	-47.4	135.5	176.8	-75.4	173.2	174.4	161.8	-0.8	114.6
14	T	34.9	Very low	32	Very low	137 Å²	137	145.4 Å²	145.4	84%	0.84	80%	0.801	S	S	*	*				177.4	152.8	102.9	22.4	0	0	0	0	111.6
15	P	32.4	Very low	31.7	Very low	112 Å²	112	148.2 Å²	148.2	73%	0.727	80%	0.799	S	S	*	*			trans	-106.2	134.4	-155.3	36.4	-26.8	0	0	0	113.6
16	L	33.2	Very low	31.7	Very low	162 Å²	162	147.2 Å²	147.2	85%	0.848	80%	0.801	S	S	*	*			trans	-147.7	119.7	162.2	-78.8	175.7	0	0	0	112.1
17	L	33.8	Very low	31.6	Very low	148 Å²	148	147 Å²	147	78%	0.775	80%	0.799	S	S	*	*			trans	61.8	94.5	142.8	-71.4	153.7	0	0	0	119.9
18	S	29.2	Very low	31.3	Very low	107 Å²	107	148 Å²	148	75%	0.748	79%	0.794	S	S	*	*				38.2	99.2	126	63.7	0	0	0	0	118.9
19	D	29.9	Very low	31.1	Very low	151 Å²	151	143.9 Å²	143.9	81%	0.807	79%	0.791	S	S	*	*			trans	-136.4	91.4	144.6	-157.5	2.5	0	0	0	108.6
20	Q	30.2	Very low	30.9	Very low	144 Å²	144	144.6 Å²	144.6	67%	0.673	79%	0.794	S	S	*	*			trans	-111.7	88	166.1	-84.9	-163.5	-0.5	0	0	107.8	R22	Q20-R22 PolarHBondContact O-N 3.39Å; Q20-R22 VanDerWaalsContact OE1-NH2 3.08Å
21	S	30.2	Very low	30.6	Very low	107 Å²	107	145.3 Å²	145.3	75%	0.748	79%	0.792	S	S	*	*			trans	-65.8	80.6	161.1	53.8	0	0	0	0	109.6	T23	S21-T23 PolarHBondContact O-N 3.31Å
22	R	28.7	Very low	30.2	Very low	196 Å²	196	141.6 Å²	141.6	74%	0.74	79%	0.787	S	S	*	*			trans	-75.5	110.4	171.4	-79.7	-176.2	-175.1	-171.3	-0.2	109.7	Q20 V24	Q20-R22 PolarHBondContact O-N 3.39Å; Q20-R22 VanDerWaalsContact OE1-NH2 3.08Å; R22-V24 PolarHBondContact O-N 3.11Å
23	T	28.7	Very low	30.2	Very low	136 Å²	136	144.4 Å²	144.4	83%	0.834	77%	0.774	S	S	*	*			trans	-52.1	118	165.5	32.2	0	0	0	0	111.5	S21	S21-T23 PolarHBondContact O-N 3.31Å
24	V	29.8	Very low	30.2	Very low	128 Å²	128	143.8 Å²	143.8	78%	0.776	77%	0.772	S	S	*	*			trans	-81.3	114.5	176.1	178.2	0	0	0	0	109.3	R22	R22-V24 PolarHBondContact O-N 3.11Å
25	K	27.1	Very low	30.3	Very low	183 Å²	183	142.7 Å²	142.7	80%	0.796	77%	0.767	S	S	*	*	P	Polyproline II helix	trans	-84.8	134.1	166.2	-72.8	178.5	178.2	174.9	0	109.2
26	P	30.4	Very low	31	Very low	129 Å²	129	140.9 Å²	140.9	84%	0.838	75%	0.745	S	S	*	*	P	Polyproline II helix	trans	-71.6	133.8	170.3	-8.5	23.7	0	0	0	110.6
27	I	31.4	Very low	31.3	Very low	158 Å²	158	138.8 Å²	138.8	81%	0.81	74%	0.735	S	S	*	*	P	Polyproline II helix	trans	-81.2	136.5	178.2	-68.8	171.6	0	0	0	110.3
28	S	28.3	Very low	31.7	Very low	90 Å²	90	132.4 Å²	132.4	63%	0.629	70%	0.702	S	S	*	*	P	Polyproline II helix	trans	-47.1	134.3	176.6	151.5	0	0	0	0	116
29	A	29.6	Very low	32.1	Very low	94 Å²	94	130.5 Å²	130.5	78%	0.777	69%	0.688	S	S	*	*	S	Bend	trans	-126.2	113.4	146.9	0	0	0	0	0	109.3
30	H	27.8	Very low	32.8	Very low	185 Å²	185	126.8 Å²	126.8	86%	0.856	67%	0.666	S	S	*	*	S	Bend	trans	57.7	108.3	172.8	-74.8	-72.9	0	0	0	119.4
31	H	27.9	Very low	33.4	Very low	174 Å²	174	121.9 Å²	121.9	81%	0.806	65%	0.647	S	S	*	*			trans	67.2	92.8	177.6	-91.7	13.4	0	0	0	115.9	R33	H31-R33 VanDerWaalsContact C-N 3.28Å; H31-R33 PolarHBondContact O-N 3.1Å
32	S	25.3	Very low	33.9	Very low	114 Å²	114	122 Å²	122	80%	0.797	64%	0.636	S	S	*	*			trans	-59.7	77.4	167.1	45.9	0	0	0	0	112.6
33	R	34.8	Very low	34.7	Very low	135 Å²	135	117.1 Å²	117.1	51%	0.509	62%	0.624	S	S	.	*			trans	-82.8	119.5	155.5	-76.3	-177.4	176.1	167.2	1.5	107.5	H31 D133	H31-R33 VanDerWaalsContact C-N 3.28Å; H31-R33 PolarHBondContact O-N 3.1Å; R33-D133 IonicContact NH1-OD1 3.95Å; R33-D133 PolarHBondContact NH1-OD1 2.89Å; R33-D133 VanDerWaalsContact NH1-OD1 3.12Å
34	R	29.7	Very low	35.8	Very low	230 Å²	230	111.5 Å²	111.5	87%	0.868	59%	0.588	S	S	*	*			trans	-42.3	143	174.7	-75.7	-179.7	178	179.8	-1.1	110.3	R36	R34-R36 PolarHBondContact O-N 2.87Å
35	P	38	Very low	36.7	Very low	113 Å²	113	108.2 Å²	108.2	73%	0.734	58%	0.58	S	S	*	*			trans	-51.2	116.5	169.5	21.1	-30.1	0	0	0	107.9	N37	P35-N37 PolarHBondContact O-N 3.3Å
36	R	48	Very low	38.4	Very low	75 Å²	75	104.7 Å²	104.7	28%	0.283	57%	0.565	S	S	.	*			trans	-74.4	80.6	177.9	-87.6	-171.4	-94.9	-174.8	-2.4	107.3	R34 S38 Y132 D133	R34-R36 PolarHBondContact O-N 2.87Å; R36-S38 VanDerWaalsContact C-N 3.31Å; R36-S38 PolarHBondContact O-N 3.26Å; R36-S38 VanDerWaalsContact O-N 3.11Å; R36-Y132 VanDerWaalsContact NH1-CD1 3.3Å; R36-D133 IonicContact CZ-OD1 2.66Å; R36-D133 IonicContact NH2-OD1 2.76Å; R36-D133 PolarHBondContact NH2-OD1 3.17Å; R36-D133 IonicContact NH2-OD2 3.79Å; R36-D133 PolarHBondContact NH2-OD2 3.39Å
37	N	38.4	Very low	39.8	Very low	118 Å²	118	101 Å²	101	63%	0.631	54%	0.538	S	S	*	.			trans	-72.7	96.5	158.7	-72.1	8.5	0	0	0	105.7	P35 P39	P35-N37 PolarHBondContact O-N 3.3Å; N37-P39 VanDerWaalsContact O-CD 3.29Å; N37-P39 WeakPolarHBondContact O-CD 3.26Å
38	S	41.9	Very low	41.2	Very low	13 Å²	13	95.8 Å²	95.8	9%	0.091	52%	0.522	C	S	.	.			trans	-78.4	112.5	165.1	49.4	0	0	0	0	106.9	R36 H40 S41	R36-S38 VanDerWaalsContact C-N 3.31Å; R36-S38 PolarHBondContact O-N 3.26Å; R36-S38 VanDerWaalsContact O-N 3.11Å; S38-H40 PolarHBondContact O-N 3Å; S38-S41 PolarHBondContact O-N 2.81Å; S38-S41 PolarHBondContact O-OG 3.4Å; S38-S41 WeakPolarHBondContact OG-CB 3.24Å; S38-S41 PolarHBondContact OG-OG 3.2Å
39	P	37.4	Very low	42.8	Very low	68 Å²	68	92.9 Å²	92.9	44%	0.442	50%	0.501	S	S	.	.	T	Hydrogen-bonded Turn	trans	-63.5	-12.3	-177.4	23.5	-31.6	0	0	0	113.2	N37	N37-P39 VanDerWaalsContact O-CD 3.29Å; N37-P39 WeakPolarHBondContact O-CD 3.26Å
40	H	45.3	Very low	44.1	Very low	73 Å²	73	95.9 Å²	95.9	34%	0.338	50%	0.504	S	S	.	.	T	Hydrogen-bonded Turn	trans	-94.1	-13.4	172.4	-71.4	-61	0	0	0	114.4	S38 D43	S38-H40 PolarHBondContact O-N 3Å; H40-D43 IonicContact CE1-OD2 4Å; H40-D43 IonicContact CG-OD2 3.5Å; H40-D43 IonicContact ND1-OD2 3.44Å; H40-D43 PolarHBondContact ND1-OD2 3.4Å; H40-D43 WeakPolarHBondContact O-CB 3.42Å; H40-D43 PolarHBondContact O-N 3.36Å
41	S	41.6	Very low	45.5	Very low	40 Å²	40	88.8 Å²	88.8	28%	0.28	47%	0.474	S	S	.	.	T	Hydrogen-bonded Turn	trans	-71.3	-22.1	161.8	70.8	0	0	0	0	111.2	S38	S38-S41 PolarHBondContact O-N 2.81Å; S38-S41 PolarHBondContact O-OG 3.4Å; S38-S41 WeakPolarHBondContact OG-CB 3.24Å; S38-S41 PolarHBondContact OG-OG 3.2Å
42	E	41.1	Very low	46.7	Very low	111 Å²	111	86.4 Å²	86.4	52%	0.519	47%	0.467	S	S	.	.	S	Bend	trans	-80	-12.7	168.9	-65.3	-177.4	161	0	0	113.3	F44 G45	E42-F44 CarbonylContact O-C 3.55Å; E42-F44 PolarHBondContact O-N 3.24Å; E42-G45 PolarHBondContact O-N 3.09Å
43	D	45.4	Very low	48.2	Very low	93 Å²	93	87 Å²	87	50%	0.497	46%	0.46	S	S	.	.	S	Bend	trans	-69.7	-22	176.8	-113.3	-12.2	0	0	0	112.3	H40 G45	H40-D43 IonicContact CE1-OD2 4Å; H40-D43 IonicContact CG-OD2 3.5Å; H40-D43 IonicContact ND1-OD2 3.44Å; H40-D43 PolarHBondContact ND1-OD2 3.4Å; H40-D43 WeakPolarHBondContact O-CB 3.42Å; H40-D43 PolarHBondContact O-N 3.36Å; D43-G45 PolarHBondContact O-N 3.03Å; D43-G45 VanDerWaalsContact O-N 3.1Å
44	F	52.3	Low	49.1	Very low	18 Å²	18	84 Å²	84	8%	0.079	47%	0.471	C	S	.	.	S	Bend	trans	-79.4	85	156.8	-59.8	-73	0	0	0	105.9	E42 K46 L198 Y388 F392	E42-F44 CarbonylContact O-C 3.55Å; E42-F44 PolarHBondContact O-N 3.24Å; F44-K46 PolarHBondContact O-N 2.84Å; F44-L198 HydrophobicContact CD1-CB 4.04Å; F44-L198 HydrophobicContact CD1-CD1 3.91Å; F44-L198 HydrophobicContact CD1-CD2 3.83Å; F44-L198 HydrophobicContact CD1-CG 4.14Å; F44-L198 HydrophobicContact CE1-CD1 3.82Å; F44-Y388 HydrophobicContact CE1-CE1 4.07Å; F44-Y388 AromaticContact CZ-CD1 3.76Å; F44-Y388 HydrophobicContact CZ-CD1 3.76Å; F44-Y388 AromaticContact CZ-CE1 3.62Å; F44-Y388 HydrophobicContact CZ-CE1 3.62Å; F44-Y388 HydrophobicContact CZ-CG 4.4Å; F44-F392 HydrophobicContact CD2-CZ 4.44Å; F44-F392 HydrophobicContact CE2-CE1 4.07Å; F44-F392 AromaticContact CE2-CZ 3.57Å; F44-F392 HydrophobicContact CE2-CZ 3.57Å; F44-F392 HydrophobicContact CZ-CZ 4.14Å
45	G	49.9	Very low	50.2	Low	59 Å²	59	79.4 Å²	79.4	61%	0.608	46%	0.46	S	S	*	.			trans	-42.4	110.5	176.3	0	0	0	0	0	108.8	E42 D43 I47	E42-G45 PolarHBondContact O-N 3.09Å; D43-G45 PolarHBondContact O-N 3.03Å; D43-G45 VanDerWaalsContact O-N 3.1Å; G45-I47 PolarHBondContact O-N 3.37Å; G45-I47 VanDerWaalsContact O-N 3.09Å
46	K	61.1	Low	51	Low	109 Å²	109	84.1 Å²	84.1	47%	0.474	46%	0.463	S	S	.	.			trans	-58.2	122.7	-169.7	-75.7	-175.8	173	-171.6	0	107.9	F44 G48 S272 D274	F44-K46 PolarHBondContact O-N 2.84Å; K46-G48 PolarHBondContact O-N 3.12Å; K46-G48 VanDerWaalsContact O-N 3.12Å; K46-S272 WeakPolarHBondContact CA-O 3.31Å; K46-D274 HydrophobicContact CB-CB 4.37Å; K46-D274 HydrophobicContact CD-CB 4.2Å; K46-D274 IonicContact NZ-OD1 2.67Å; K46-D274 PolarHBondContact NZ-OD1 3.39Å
47	I	61.3	Low	51.2	Low	52 Å²	52	87.5 Å²	87.5	27%	0.267	49%	0.486	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-75.6	108.9	175	-57.4	175.7	0	0	0	105.5	G45 V49 T66 S272 D274	G45-I47 PolarHBondContact O-N 3.37Å; G45-I47 VanDerWaalsContact O-N 3.09Å; I47-V49 PolarHBondContact O-N 3.32Å; I47-T66 HydrophobicContact CG2-CG2 4.41Å; I47-S272 PolarHBondContact N-O 3.15Å; I47-D274 PolarHBondContact O-N 3.11Å; I47-D274 VanDerWaalsContact O-N 3.09Å
48	G	59.7	Low	52.5	Low	47 Å²	47	90.4 Å²	90.4	49%	0.485	50%	0.498	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-60.8	123.2	175.3	0	0	0	0	0	109.5	K46 N50	K46-G48 PolarHBondContact O-N 3.12Å; K46-G48 VanDerWaalsContact O-N 3.12Å; G48-N50 PolarHBondContact O-N 2.91Å
49	V	61.8	Low	54.2	Low	29 Å²	29	94 Å²	94	18%	0.176	51%	0.512	C	S	.	.			trans	-87.1	96.3	171.7	-172.1	0	0	0	0	106.2	I47 V51 F67 R273 D274	I47-V49 PolarHBondContact O-N 3.32Å; V49-V51 HydrophobicContact CB-CG2 4.38Å; V49-V51 HydrophobicContact CG1-CG2 3.64Å; V49-V51 PolarHBondContact O-N 2.7Å; V49-F67 HydrophobicContact CG1-CE2 4.08Å; V49-F67 HydrophobicContact CG1-CZ 3.95Å; V49-F67 HydrophobicContact CG2-CE1 4.34Å; V49-F67 HydrophobicContact CG2-CZ 4.04Å; V49-R273 HydrophobicContact CG2-CB 4Å; V49-D274 WeakPolarHBondContact CG2-O 3.15Å
50	N	56.6	Low	56.4	Low	157 Å²	157	92.1 Å²	92.1	84%	0.84	50%	0.501	S	S	*	.			trans	-67.6	100.3	171.9	-75.3	-18.6	0	0	0	107.9	G48	G48-N50 PolarHBondContact O-N 2.91Å
51	V	57.4	Low	58.3	Low	37 Å²	37	96.4 Å²	96.4	22%	0.224	52%	0.519	C	S	.	.			trans	-100.2	106.1	174.4	-174.9	0	0	0	0	108.2	V49 L53 L282	V49-V51 HydrophobicContact CB-CG2 4.38Å; V49-V51 HydrophobicContact CG1-CG2 3.64Å; V49-V51 PolarHBondContact O-N 2.7Å; V51-L53 HydrophobicContact CG1-CD2 4.39Å; V51-L53 PolarHBondContact O-N 3.05Å; V51-L282 HydrophobicContact CB-CD2 4.31Å; V51-L282 HydrophobicContact CG1-CD2 3.89Å; V51-L282 HydrophobicContact CG2-CD2 4.06Å
52	D	54.3	Low	60.3	Low	124 Å²	124	101.9 Å²	101.9	66%	0.663	54%	0.54	S	S	*	.			trans	-67.6	100.5	161.3	-72.1	-32.3	0	0	0	107.8	G54 E55	D52-G54 PolarHBondContact O-N 3.23Å; D52-E55 PolarHBondContact O-N 3.03Å
53	L	56.4	Low	62.2	Low	126 Å²	126	98.3 Å²	98.3	66%	0.66	52%	0.522	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.9	-3.5	179.6	-71	164.4	0	0	0	113.4	V51	V51-L53 HydrophobicContact CG1-CD2 4.39Å; V51-L53 PolarHBondContact O-N 3.05Å
54	G	52.7	Low	64.2	Low	71 Å²	71	94.8 Å²	94.8	73%	0.732	50%	0.503	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.6	-22.5	179.2	0	0	0	0	0	115.3	D52 R56	D52-G54 PolarHBondContact O-N 3.23Å; G54-R56 PolarHBondContact O-N 3.07Å
55	E	54.3	Low	65.8	Low	135 Å²	135	102 Å²	102	63%	0.631	53%	0.53	S	S	*	.			trans	-90.6	87.2	178.5	-77.7	-170.9	157.3	0	0	110.9	D52 N57 R63	D52-E55 PolarHBondContact O-N 3.03Å; E55-N57 VanDerWaalsContact C-N 3.31Å; E55-N57 PolarHBondContact O-N 3.03Å; E55-R63 IonicContact OE2-NH2 3.67Å
56	R	53.5	Low	67.4	Low	211 Å²	211	101.1 Å²	101.1	80%	0.796	51%	0.513	S	S	*	.			trans	-76.4	0	-178.5	-89.5	-173	-176	-178.8	1.9	115.8	G54	G54-R56 PolarHBondContact O-N 3.07Å
57	N	52.6	Low	68.5	Low	146 Å²	146	96.3 Å²	96.3	78%	0.781	49%	0.492	S	S	*	.	S	Bend	trans	-150.3	135.8	-170.8	-81	-41	0	0	0	114.8	E55	E55-N57 VanDerWaalsContact C-N 3.31Å; E55-N57 PolarHBondContact O-N 3.03Å
58	M	65.1	Low	69.7	Low	180 Å²	180	94.9 Å²	94.9	89%	0.887	49%	0.485	S	S	*	.	S	Bend	trans	83	131.3	172.1	-53.4	-164.9	-56	0	0	117.3	S60	M58-S60 PolarHBondContact O-N 2.91Å
59	F	77.7	Confident	70.9	Confident	88 Å²	88	92.7 Å²	92.7	39%	0.386	46%	0.463	S	S	.	.			trans	-44.6	130.4	174.7	166.7	-91	0	0	0	111.8	F61 L64 Y289 I292	F59-F61 HydrophobicContact CD1-CE2 4.43Å; F59-F61 AromaticContact CE1-CD1 3.9Å; F59-F61 HydrophobicContact CE1-CD1 3.9Å; F59-F61 HydrophobicContact CE1-CD2 4.06Å; F59-F61 AromaticContact CE1-CE1 3.78Å; F59-F61 HydrophobicContact CE1-CE1 3.78Å; F59-F61 AromaticContact CE1-CE2 3.94Å; F59-F61 HydrophobicContact CE1-CE2 3.94Å; F59-F61 HydrophobicContact CE1-CG 4.04Å; F59-F61 AromaticContact CE1-CZ 3.8Å; F59-F61 HydrophobicContact CE1-CZ 3.8Å; F59-F61 HydrophobicContact CZ-CD1 4.33Å; F59-F61 HydrophobicContact CZ-CE1 4.29Å; F59-L64 HydrophobicContact CE2-CB 4.39Å; F59-L64 HydrophobicContact CE2-CD2 4.27Å; F59-L64 HydrophobicContact CZ-CB 4.29Å; F59-L64 HydrophobicContact CZ-CD2 3.76Å; F59-Y289 HydrophobicContact CD2-CD1 4.48Å; F59-Y289 AromaticContact CD2-CE1 3.76Å; F59-Y289 HydrophobicContact CD2-CE1 3.76Å; F59-Y289 HydrophobicContact CE2-CD1 4.25Å; F59-Y289 AromaticContact CE2-CE1 3.85Å; F59-Y289 HydrophobicContact CE2-CE1 3.85Å; F59-I292 HydrophobicContact CD2-CD1 4.12Å; F59-I292 HydrophobicContact CE2-CD1 3.73Å
60	S	83.6	Confident	72.2	Confident	29 Å²	29	91.3 Å²	91.3	20%	0.203	46%	0.455	C	S	.	.			trans	-112.5	123.9	179.2	172.3	0	0	0	0	111	M58 Q62 R63 L64 Y289	M58-S60 PolarHBondContact O-N 2.91Å; S60-Q62 PolarHBondContact O-N 3.47Å; S60-Q62 PolarHBondContact OG-N 3.08Å; S60-R63 PolarHBondContact O-N 3.31Å; S60-R63 PolarHBondContact OG-N 3.43Å; S60-L64 PolarHBondContact O-N 3.38Å; S60-Y289 PolarHBondContact N-OH 3.45Å
61	F	85.2	Confident	73.9	Confident	162 Å²	162	83.9 Å²	83.9	71%	0.711	42%	0.415	S	S	*	.	H	α-helix	trans	-62.2	-31.8	174.1	-76.7	-79.6	0	0	0	112.5	F59 L64 W65	F59-F61 HydrophobicContact CD1-CE2 4.43Å; F59-F61 AromaticContact CE1-CD1 3.9Å; F59-F61 HydrophobicContact CE1-CD1 3.9Å; F59-F61 HydrophobicContact CE1-CD2 4.06Å; F59-F61 AromaticContact CE1-CE1 3.78Å; F59-F61 HydrophobicContact CE1-CE1 3.78Å; F59-F61 AromaticContact CE1-CE2 3.94Å; F59-F61 HydrophobicContact CE1-CE2 3.94Å; F59-F61 HydrophobicContact CE1-CG 4.04Å; F59-F61 AromaticContact CE1-CZ 3.8Å; F59-F61 HydrophobicContact CE1-CZ 3.8Å; F59-F61 HydrophobicContact CZ-CD1 4.33Å; F59-F61 HydrophobicContact CZ-CE1 4.29Å; F61-L64 PolarHBondContact O-N 3.32Å; F61-W65 WeakPolarHBondContact O-CB 3.24Å; F61-W65 PolarHBondContact O-N 3.44Å
62	Q	83.5	Confident	75.3	Confident	155 Å²	155	84.3 Å²	84.3	72%	0.724	41%	0.414	S	S	*	.	H	α-helix	trans	-68.1	-40.1	176.2	-175.3	179.4	-2.1	0	0	111.4	S60 W65 T66	S60-Q62 PolarHBondContact O-N 3.47Å; S60-Q62 PolarHBondContact OG-N 3.08Å; Q62-W65 PolarHBondContact O-N 3.23Å; Q62-T66 PolarHBondContact O-N 3.04Å; Q62-T66 VanDerWaalsContact O-N 3.14Å; Q62-T66 PolarHBondContact O-OG1 3.25Å
63	R	82.2	Confident	76.9	Confident	37 Å²	37	78.6 Å²	78.6	14%	0.14	38%	0.383	C	S	.	.	H	α-helix	trans	-63.7	-48	172.2	-68.5	-173.8	-173.5	-179.4	5.4	110.1	E55 S60 W65 T66 F67 E285 Y289	E55-R63 IonicContact OE2-NH2 3.67Å; S60-R63 PolarHBondContact O-N 3.31Å; S60-R63 PolarHBondContact OG-N 3.43Å; R63-W65 VanDerWaalsContact C-N 3.31Å; R63-W65 PolarHBondContact O-N 2.88Å; R63-T66 WeakPolarHBondContact O-CB 3.46Å; R63-T66 PolarHBondContact O-N 3.47Å; R63-F67 VanDerWaalsContact O-CD2 3.25Å; R63-F67 WeakPolarHBondContact O-CD2 3.25Å; R63-F67 PolarHBondContact O-N 3.34Å; R63-F67 VanDerWaalsContact O-N 3.12Å; R63-E285 WeakPolarHBondContact CD-OE1 3.44Å; R63-E285 IonicContact CZ-OE1 4Å; R63-E285 IonicContact NE-OE1 3.27Å; R63-E285 IonicContact NH1-OE1 3.74Å; R63-E285 PolarHBondContact NH1-OE1 3.2Å; R63-E285 IonicContact NH1-OE2 2.73Å; R63-Y289 HydrophobicContact CB-CE1 4.14Å; R63-Y289 HydrophobicContact CB-CE2 3.86Å
64	L	87	Confident	78.7	Confident	19 Å²	19	72.6 Å²	72.6	10%	0.099	35%	0.352	C	S	.	.	H	α-helix	trans	-53.2	-48.5	175.5	179.6	65.1	0	0	0	111.3	F59 S60 F61 T66 F67 T68 Y289 I292 E293	F59-L64 HydrophobicContact CE2-CB 4.39Å; F59-L64 HydrophobicContact CE2-CD2 4.27Å; F59-L64 HydrophobicContact CZ-CB 4.29Å; F59-L64 HydrophobicContact CZ-CD2 3.76Å; S60-L64 PolarHBondContact O-N 3.38Å; F61-L64 PolarHBondContact O-N 3.32Å; L64-T66 PolarHBondContact O-N 2.97Å; L64-F67 CarbonylContact O-C 3.59Å; L64-F67 PolarHBondContact O-N 2.9Å; L64-T68 PolarHBondContact O-N 3.42Å; L64-T68 PolarHBondContact O-OG1 3.35Å; L64-Y289 HydrophobicContact CB-CD1 3.94Å; L64-Y289 HydrophobicContact CB-CE1 4.11Å; L64-Y289 HydrophobicContact CD1-CD1 3.97Å; L64-I292 HydrophobicContact CD1-CB 4.37Å; L64-I292 HydrophobicContact CD1-CG2 4.03Å; L64-I292 HydrophobicContact CD2-CG2 4.27Å; L64-E293 HydrophobicContact CD1-CB 4.42Å
65	W	85.2	Confident	80.5	Confident	168 Å²	168	69.2 Å²	69.2	64%	0.636	32%	0.317	S	S	*	.	H	α-helix	trans	-59.5	-31.1	178.5	-174.6	-107.8	0	0	0	114.1	F61 Q62 R63 R199	F61-W65 WeakPolarHBondContact O-CB 3.24Å; F61-W65 PolarHBondContact O-N 3.44Å; Q62-W65 PolarHBondContact O-N 3.23Å; R63-W65 VanDerWaalsContact C-N 3.31Å; R63-W65 PolarHBondContact O-N 2.88Å; W65-R199 VanDerWaalsContact NE1-NH2 3.15Å; W65-R199 PolarHBondContact O-NH2 3.03Å
66	T	83.3	Confident	82.2	Confident	41 Å²	41	63 Å²	63	25%	0.252	29%	0.288	S	S	.	.	H	α-helix	trans	-71	-38.3	175.9	-54.7	0	0	0	0	111.1	I47 Q62 R63 L64	I47-T66 HydrophobicContact CG2-CG2 4.41Å; Q62-T66 PolarHBondContact O-N 3.04Å; Q62-T66 VanDerWaalsContact O-N 3.14Å; Q62-T66 PolarHBondContact O-OG1 3.25Å; R63-T66 WeakPolarHBondContact O-CB 3.46Å; R63-T66 PolarHBondContact O-N 3.47Å; L64-T66 PolarHBondContact O-N 2.97Å
67	F	84.8	Confident	83.9	Confident	8 Å²	8	53 Å²	53	4%	0.035	25%	0.25	C	S	.	.	H	α-helix	trans	-76.4	-29.4	175.1	-74.8	-78.8	0	0	0	112.6	V49 R63 L64 G69 P70 R273 I275 A286 Y289 Y290	V49-F67 HydrophobicContact CG1-CE2 4.08Å; V49-F67 HydrophobicContact CG1-CZ 3.95Å; V49-F67 HydrophobicContact CG2-CE1 4.34Å; V49-F67 HydrophobicContact CG2-CZ 4.04Å; R63-F67 VanDerWaalsContact O-CD2 3.25Å; R63-F67 WeakPolarHBondContact O-CD2 3.25Å; R63-F67 PolarHBondContact O-N 3.34Å; R63-F67 VanDerWaalsContact O-N 3.12Å; L64-F67 CarbonylContact O-C 3.59Å; L64-F67 PolarHBondContact O-N 2.9Å; F67-G69 PolarHBondContact O-N 3.34Å; F67-P70 WeakPolarHBondContact O-CD 3.32Å; F67-R273 HydrophobicContact CD1-CB 4.41Å; F67-R273 HydrophobicContact CD1-CG 4.07Å; F67-R273 HydrophobicContact CE1-CB 4.18Å; F67-R273 HydrophobicContact CE1-CG 4.31Å; F67-I275 HydrophobicContact CE1-CD1 4.29Å; F67-I275 HydrophobicContact CE1-CG1 4.5Å; F67-A286 HydrophobicContact CE1-CB 3.95Å; F67-A286 HydrophobicContact CZ-CB 4.19Å; F67-Y289 AromaticContact CD2-CD2 3.74Å; F67-Y289 HydrophobicContact CD2-CD2 3.74Å; F67-Y289 AromaticContact CD2-CG 3.87Å; F67-Y289 HydrophobicContact CD2-CG 3.87Å; F67-Y289 AromaticContact CE2-CD2 3.79Å; F67-Y289 HydrophobicContact CE2-CD2 3.79Å; F67-Y289 HydrophobicContact CE2-CE2 4.42Å; F67-Y289 HydrophobicContact CE2-CG 4.39Å; F67-Y289 HydrophobicContact CG-CG 4.43Å; F67-Y290 HydrophobicContact CB-CE1 4.45Å; F67-Y290 HydrophobicContact CD1-CD1 4.44Å; F67-Y290 HydrophobicContact CD1-CD2 4.43Å; F67-Y290 AromaticContact CD1-CE1 3.9Å; F67-Y290 HydrophobicContact CD1-CE1 3.9Å; F67-Y290 AromaticContact CD1-CE2 3.94Å; F67-Y290 HydrophobicContact CD1-CE2 3.94Å; F67-Y290 AromaticContact CD1-CZ 3.67Å; F67-Y290 HydrophobicContact CE1-CE2 4.16Å
68	T	86.3	Confident	85.8	Confident	22 Å²	22	46 Å²	46	14%	0.135	21%	0.213	C	C	.	.			trans	-52.8	130.9	177.4	-56.4	0	0	0	0	111.9	L64 F72 R199 R273 E293	L64-T68 PolarHBondContact O-N 3.42Å; L64-T68 PolarHBondContact O-OG1 3.35Å; T68-F72 HydrophobicContact CG2-CD2 3.72Å; T68-F72 HydrophobicContact CG2-CE2 3.61Å; T68-R199 PolarHBondContact O-NH1 2.83Å; T68-R273 PolarHBondContact O-NH2 3.05Å; T68-E293 HydrophobicContact CG2-CG 4.45Å
69	G	86	Confident	87.1	Confident	2 Å²	2	37.6 Å²	37.6	2%	0.021	17%	0.172	C	C	.	.	S	Bend	trans	148.1	-65.1	-177.4	0	0	0	0	0	113.6	F67 G71 F72 L73 E202 E293	F67-G69 PolarHBondContact O-N 3.34Å; G69-G71 VanDerWaalsContact C-N 3.33Å; G69-G71 PolarHBondContact O-N 3.24Å; G69-F72 PolarHBondContact O-N 3.44Å; G69-L73 PolarHBondContact O-N 3.22Å; G69-E202 VanDerWaalsContact CA-OE1 3.31Å; G69-E202 WeakPolarHBondContact CA-OE1 3.49Å; G69-E293 VanDerWaalsContact C-OE1 3.25Å; G69-E293 WeakPolarHBondContact CA-OE1 3.35Å; G69-E293 PolarHBondContact N-OE1 2.99Å
70	P	88.7	Confident	87.7	Confident	0 Å²	0	33.4 Å²	33.4	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-61.8	-38	-174.3	-29.2	43.1	0	0	0	113.5	F67 L73 M74 L269 V270 Y290 E293	F67-P70 WeakPolarHBondContact O-CD 3.32Å; P70-L73 PolarHBondContact O-N 2.93Å; P70-M74 VanDerWaalsContact O-CB 3.26Å; P70-M74 WeakPolarHBondContact O-CB 3.4Å; P70-M74 PolarHBondContact O-N 3.46Å; P70-L269 HydrophobicContact CB-CB 3.78Å; P70-L269 HydrophobicContact CG-CB 4.35Å; P70-V270 HydrophobicContact CB-CG1 4.42Å; P70-Y290 HydrophobicContact CB-CE1 4.39Å; P70-Y290 HydrophobicContact CG-CE1 3.87Å; P70-E293 WeakPolarHBondContact CD-OE1 3.16Å
71	G	91.2	Very high	88	Confident	0 Å²	0	32 Å²	32	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-66.4	-40.3	178.1	0	0	0	0	0	112	G69 M74 S75 E293 A297	G69-G71 VanDerWaalsContact C-N 3.33Å; G69-G71 PolarHBondContact O-N 3.24Å; G71-M74 PolarHBondContact O-N 2.66Å; G71-S75 WeakPolarHBondContact O-CB 3.41Å; G71-S75 PolarHBondContact O-N 2.91Å; G71-E293 WeakPolarHBondContact CA-OE1 3.44Å; G71-E293 PolarHBondContact N-OE1 3.45Å; G71-A297 WeakPolarHBondContact O-CB 3.41Å
72	F	88.5	Confident	88.2	Confident	47 Å²	47	24.3 Å²	24.3	21%	0.206	11%	0.11	C	C	.	.	H	α-helix	trans	-68.6	-39.9	174.9	-79.8	-84.3	0	0	0	112.4	T68 G69 M74 S75 I76 I209 A297	T68-F72 HydrophobicContact CG2-CD2 3.72Å; T68-F72 HydrophobicContact CG2-CE2 3.61Å; G69-F72 PolarHBondContact O-N 3.44Å; F72-M74 VanDerWaalsContact C-N 3.32Å; F72-M74 PolarHBondContact O-N 3.26Å; F72-S75 PolarHBondContact O-N 3.29Å; F72-S75 PolarHBondContact O-OG 2.97Å; F72-I76 WeakPolarHBondContact O-CG1 3.29Å; F72-I76 PolarHBondContact O-N 3.34Å; F72-I209 HydrophobicContact CD1-CD1 4.26Å; F72-A297 HydrophobicContact CD1-CB 4.24Å; F72-A297 HydrophobicContact CD2-CB 4.43Å; F72-A297 HydrophobicContact CE1-CB 4.44Å; F72-A297 HydrophobicContact CG-CB 4.25Å
73	L	88	Confident	88.7	Confident	3 Å²	3	17 Å²	17	2%	0.016	8%	0.075	C	C	.	.	H	α-helix	trans	-62.1	-41.8	173.4	-81.9	166.5	0	0	0	112.2	G69 P70 S75 I76 L198 L201 E202 F205 L269 T385	G69-L73 PolarHBondContact O-N 3.22Å; P70-L73 PolarHBondContact O-N 2.93Å; L73-S75 VanDerWaalsContact C-N 3.35Å; L73-I76 HydrophobicContact CD2-CD1 4.17Å; L73-L198 HydrophobicContact CD1-CD1 3.75Å; L73-L201 HydrophobicContact CD1-CD2 4.48Å; L73-L201 HydrophobicContact CD2-CD2 3.68Å; L73-E202 HydrophobicContact CD1-CG 3.75Å; L73-E202 HydrophobicContact CG-CG 4.26Å; L73-F205 HydrophobicContact CD2-CD2 3.34Å; L73-F205 HydrophobicContact CD2-CE2 3.35Å; L73-F205 HydrophobicContact CG-CD2 4.4Å; L73-L269 HydrophobicContact CB-CD1 3.56Å; L73-L269 HydrophobicContact CD1-CD1 4.01Å; L73-L269 HydrophobicContact CD1-CD2 4.11Å; L73-L269 HydrophobicContact CG-CD1 4.41Å; L73-T385 WeakPolarHBondContact O-CG2 3.15Å
74	M	92.5	Very high	89.2	Confident	0 Å²	0	15.3 Å²	15.3	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-65.6	-37.7	175.2	175.8	-80.5	-67.5	0	0	111.8	P70 G71 F72 I76 A77 Y78 Q113 N262 H266 L298	P70-M74 VanDerWaalsContact O-CB 3.26Å; P70-M74 WeakPolarHBondContact O-CB 3.4Å; P70-M74 PolarHBondContact O-N 3.46Å; G71-M74 PolarHBondContact O-N 2.66Å; F72-M74 VanDerWaalsContact C-N 3.32Å; F72-M74 PolarHBondContact O-N 3.26Å; M74-I76 VanDerWaalsContact C-N 3.25Å; M74-I76 PolarHBondContact O-N 3.34Å; M74-A77 PolarHBondContact O-N 3Å; M74-Y78 HydrophobicContact SD-CD2 4.18Å; M74-Y78 HydrophobicContact SD-CE2 3.61Å; M74-Q113 HydrophobicContact CE-CB 4.07Å; M74-Q113 HydrophobicContact CE-CG 4.01Å; M74-Q113 HydrophobicContact CG-CG 4.25Å; M74-Q113 HydrophobicContact SD-CB 4.32Å; M74-Q113 VanDerWaalsContact SD-CD 3.52Å; M74-Q113 HydrophobicContact SD-CG 3.61Å; M74-N262 WeakPolarHBondContact CG-OD1 3.36Å; M74-N262 PolarHBondContact O-ND2 3.49Å; M74-H266 HydrophobicContact CB-CB 4.24Å; M74-H266 HydrophobicContact CG-CB 3.86Å; M74-L298 HydrophobicContact CE-CD1 3.95Å; M74-L298 HydrophobicContact CE-CD2 4.1Å; M74-L298 HydrophobicContact CE-CG 3.9Å; M74-L298 HydrophobicContact SD-CD1 4.4Å; M74-L298 HydrophobicContact SD-CD2 3.94Å; M74-L298 HydrophobicContact SD-CG 4.37Å
75	S	92.4	Very high	89.4	Confident	0 Å²	0	14.5 Å²	14.5	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-70.8	-18.6	-177.6	77.8	0	0	0	0	113.7	G71 F72 L73 A77 Y78 S301	G71-S75 WeakPolarHBondContact O-CB 3.41Å; G71-S75 PolarHBondContact O-N 2.91Å; F72-S75 PolarHBondContact O-N 3.29Å; F72-S75 PolarHBondContact O-OG 2.97Å; L73-S75 VanDerWaalsContact C-N 3.35Å; S75-A77 PolarHBondContact O-N 2.92Å; S75-Y78 WeakPolarHBondContact O-CA 3.39Å; S75-Y78 VanDerWaalsContact O-CB 3.3Å; S75-Y78 WeakPolarHBondContact O-CB 3.4Å; S75-Y78 PolarHBondContact O-N 2.86Å; S75-S301 WeakPolarHBondContact CB-OG 3.29Å
76	I	88.2	Confident	89.7	Confident	5 Å²	5	6.5 Å²	6.5	3%	0.026	4%	0.035	C	C	.	.	G	3₁₀ helix	trans	-57.2	-36.2	173	-69.3	161.6	0	0	0	111.4	F72 L73 M74 Y78 L79 D80 F205 I209 T385	F72-I76 WeakPolarHBondContact O-CG1 3.29Å; F72-I76 PolarHBondContact O-N 3.34Å; L73-I76 HydrophobicContact CD2-CD1 4.17Å; M74-I76 VanDerWaalsContact C-N 3.25Å; M74-I76 PolarHBondContact O-N 3.34Å; I76-Y78 PolarHBondContact O-N 3.12Å; I76-Y78 VanDerWaalsContact O-N 3.13Å; I76-L79 CarbonylContact O-C 3.59Å; I76-L79 WeakPolarHBondContact O-CA 3.42Å; I76-L79 PolarHBondContact O-N 3.29Å; I76-D80 PolarHBondContact O-N 3.39Å; I76-D80 VanDerWaalsContact O-N 3.12Å; I76-F205 HydrophobicContact CD1-CB 3.74Å; I76-F205 HydrophobicContact CD1-CD1 3.8Å; I76-F205 HydrophobicContact CD1-CD2 3.53Å; I76-F205 HydrophobicContact CD1-CE1 4.25Å; I76-F205 HydrophobicContact CD1-CE2 3.89Å; I76-F205 HydrophobicContact CD1-CG 3.43Å; I76-F205 VanDerWaalsContact CD1-CG 3.43Å; I76-F205 HydrophobicContact CD1-CZ 4.23Å; I76-I209 HydrophobicContact CG1-CD1 4.2Å; I76-T385 HydrophobicContact CB-CG2 4.28Å; I76-T385 HydrophobicContact CD1-CG2 4.36Å; I76-T385 HydrophobicContact CG2-CG2 4.22Å
77	A	90.4	Very high	90.2	Very high	0 Å²	0	4.6 Å²	4.6	0%	0	2%	0.023	C	C	.	.	G	3₁₀ helix	trans	-65.6	-15	177.2	0	0	0	0	0	112.4	M74 S75 M259 N262	M74-A77 PolarHBondContact O-N 3Å; S75-A77 PolarHBondContact O-N 2.92Å; A77-M259 HydrophobicContact CB-SD 3.44Å; A77-M259 WeakPolarHBondContact CB-SD 3.5Å; A77-N262 HydrophobicContact CB-CB 4.15Å; A77-N262 WeakPolarHBondContact CB-ND2 3.44Å
78	Y	92.3	Very high	90.6	Very high	1 Å²	1	4.2 Å²	4.2	0%	0.004	2%	0.021	C	C	.	.	G	3₁₀ helix	trans	-90.8	-2.1	172.3	-67.9	-107.4	0	0	0	112.3	M74 S75 I76 N83 G109 V257 L298 N305	M74-Y78 HydrophobicContact SD-CD2 4.18Å; M74-Y78 HydrophobicContact SD-CE2 3.61Å; S75-Y78 WeakPolarHBondContact O-CA 3.39Å; S75-Y78 VanDerWaalsContact O-CB 3.3Å; S75-Y78 WeakPolarHBondContact O-CB 3.4Å; S75-Y78 PolarHBondContact O-N 2.86Å; I76-Y78 PolarHBondContact O-N 3.12Å; I76-Y78 VanDerWaalsContact O-N 3.13Å; Y78-N83 VanDerWaalsContact C-ND2 3.33Å; Y78-N83 PolarHBondContact O-ND2 3.48Å; Y78-G109 VanDerWaalsContact OH-CA 3.26Å; Y78-G109 WeakPolarHBondContact OH-CA 3.42Å; Y78-V257 HydrophobicContact CD1-CG1 3.8Å; Y78-V257 WeakPolarHBondContact CD1-O 3.46Å; Y78-V257 HydrophobicContact CE1-CG1 3.58Å; Y78-V257 WeakPolarHBondContact CE1-O 2.88Å; Y78-V257 VanDerWaalsContact CZ-O 3.28Å; Y78-L298 HydrophobicContact CD1-CD2 3.85Å; Y78-L298 HydrophobicContact CD2-CD2 3.37Å; Y78-L298 HydrophobicContact CE1-CD2 3.9Å; Y78-L298 HydrophobicContact CE2-CD2 3.44Å; Y78-L298 VanDerWaalsContact CE2-CD2 3.44Å; Y78-L298 HydrophobicContact CG-CD2 3.6Å; Y78-N305 PolarHBondContact O-ND2 2.92Å; Y78-N305 PolarHBondContact O-OD1 3.21Å
79	L	91.7	Very high	90.9	Very high	3 Å²	3	3.4 Å²	3.4	2%	0.016	2%	0.016	C	C	.	.	S	Bend	trans	-130.3	16	-176.8	-64.4	175.1	0	0	0	111.5	I76 I84 I209 M212 I304 N305 A378	I76-L79 CarbonylContact O-C 3.59Å; I76-L79 WeakPolarHBondContact O-CA 3.42Å; I76-L79 PolarHBondContact O-N 3.29Å; L79-I84 WeakPolarHBondContact O-CD1 3.41Å; L79-I209 HydrophobicContact CD1-CD1 4.38Å; L79-I209 HydrophobicContact CD1-CG1 3.99Å; L79-I209 HydrophobicContact CD1-CG2 4.04Å; L79-M212 HydrophobicContact CB-CE 4.14Å; L79-I304 HydrophobicContact CD1-CD1 3.71Å; L79-I304 HydrophobicContact CD2-CB 3.77Å; L79-I304 HydrophobicContact CD2-CD1 3.86Å; L79-I304 HydrophobicContact CD2-CG1 4.43Å; L79-I304 HydrophobicContact CD2-CG2 3.67Å; L79-I304 HydrophobicContact CG-CD1 4.47Å; L79-N305 WeakPolarHBondContact CD2-OD1 3.48Å; L79-A378 WeakPolarHBondContact O-CB 3.4Å
80	D	90.9	Very high	91.2	Very high	0 Å²	0	3.4 Å²	3.4	0%	0	2%	0.016	C	C	.	.	S	Bend	trans	-74.7	166.3	178.6	80.1	-28.6	0	0	0	110.7	I76 G82 N83 I84 M259	I76-D80 PolarHBondContact O-N 3.39Å; I76-D80 VanDerWaalsContact O-N 3.12Å; D80-G82 PolarHBondContact O-N 2.87Å; D80-N83 PolarHBondContact O-N 2.86Å; D80-N83 VanDerWaalsContact O-N 3.16Å; D80-N83 WeakPolarHBondContact OD1-CB 3.38Å; D80-N83 PolarHBondContact OD1-N 3.22Å; D80-I84 WeakPolarHBondContact O-CG1 3.27Å; D80-I84 PolarHBondContact O-N 3.43Å; D80-M259 WeakPolarHBondContact OD2-CE 3.34Å
81	P	89.9	Confident	91.4	Very high	0 Å²	0	3.4 Å²	3.4	0%	0	2%	0.016	C	C	.	.	H	α-helix	trans	-57.2	-32.8	-178.9	-28.4	37.9	0	0	0	113.8	E85 L352 A378	P81-E85 VanDerWaalsContact O-CB 3.31Å; P81-E85 WeakPolarHBondContact O-CB 3.49Å; P81-E85 PolarHBondContact O-N 3.45Å; P81-L352 HydrophobicContact CB-CD1 3.91Å; P81-A378 HydrophobicContact CG-CB 4.3Å
82	G	89.9	Confident	91.4	Very high	0 Å²	0	3.9 Å²	3.9	0%	0	2%	0.02	C	C	.	.	H	α-helix	trans	-63.3	-43.8	177.2	0	0	0	0	0	112.9	D80 S86 N439	D80-G82 PolarHBondContact O-N 2.87Å; G82-S86 PolarHBondContact O-N 2.92Å; G82-S86 VanDerWaalsContact O-N 3.13Å; G82-N439 PolarHBondContact O-ND2 3.11Å
83	N	92.7	Very high	91.5	Very high	0 Å²	0	4.1 Å²	4.1	0%	0	2%	0.023	C	C	.	.	H	α-helix	trans	-71.2	-43.8	175.6	-160.6	-1.1	0	0	0	112.4	Y78 D80 E85 S86 D87 A256 N305	Y78-N83 VanDerWaalsContact C-ND2 3.33Å; Y78-N83 PolarHBondContact O-ND2 3.48Å; D80-N83 PolarHBondContact O-N 2.86Å; D80-N83 VanDerWaalsContact O-N 3.16Å; D80-N83 WeakPolarHBondContact OD1-CB 3.38Å; D80-N83 PolarHBondContact OD1-N 3.22Å; N83-E85 VanDerWaalsContact C-N 3.27Å; N83-E85 PolarHBondContact O-N 2.82Å; N83-S86 WeakPolarHBondContact O-CB 3.44Å; N83-S86 PolarHBondContact O-N 3.03Å; N83-S86 VanDerWaalsContact O-N 3.15Å; N83-D87 WeakPolarHBondContact O-CB 3.39Å; N83-D87 PolarHBondContact O-N 3.33Å; N83-A256 HydrophobicContact CB-CB 4.47Å; N83-N305 PolarHBondContact ND2-ND2 3.3Å; N83-N305 VanDerWaalsContact ND2-ND2 3.14Å
84	I	92.3	Very high	91.6	Very high	2 Å²	2	4 Å²	4	1%	0.01	2%	0.022	C	C	.	.	H	α-helix	trans	-58	-42	177.2	-66.3	171.5	0	0	0	111	L79 D80 D87 L88 M212 V308 L352 W371 L375 A378	L79-I84 WeakPolarHBondContact O-CD1 3.41Å; D80-I84 WeakPolarHBondContact O-CG1 3.27Å; D80-I84 PolarHBondContact O-N 3.43Å; I84-D87 PolarHBondContact O-N 2.88Å; I84-L88 VanDerWaalsContact O-CB 3.3Å; I84-L88 WeakPolarHBondContact O-CB 3.41Å; I84-L88 PolarHBondContact O-N 3.47Å; I84-M212 HydrophobicContact CD1-CE 3.7Å; I84-V308 HydrophobicContact CG2-CG1 4.4Å; I84-L352 HydrophobicContact CB-CD2 4.33Å; I84-L352 HydrophobicContact CG2-CD2 3.82Å; I84-W371 HydrophobicContact CG2-CH2 3.38Å; I84-W371 HydrophobicContact CG2-CZ2 4.16Å; I84-W371 HydrophobicContact CG2-CZ3 3.99Å; I84-L375 HydrophobicContact CD1-CD2 4.2Å; I84-L375 HydrophobicContact CG2-CD2 4.3Å; I84-A378 HydrophobicContact CD1-CB 4.23Å
85	E	91.5	Very high	91.6	Very high	2 Å²	2	5.8 Å²	5.8	1%	0.009	3%	0.032	C	C	.	.	H	α-helix	trans	-66	-44.2	177.2	-171.2	167.5	174	0	0	111.7	P81 N83 D87 L88 Q89 L352 N435	P81-E85 VanDerWaalsContact O-CB 3.31Å; P81-E85 WeakPolarHBondContact O-CB 3.49Å; P81-E85 PolarHBondContact O-N 3.45Å; N83-E85 VanDerWaalsContact C-N 3.27Å; N83-E85 PolarHBondContact O-N 2.82Å; E85-D87 VanDerWaalsContact C-N 3.32Å; E85-D87 PolarHBondContact O-N 3.09Å; E85-L88 PolarHBondContact O-N 3.31Å; E85-Q89 WeakPolarHBondContact O-CB 3.27Å; E85-Q89 WeakPolarHBondContact O-CG 3.29Å; E85-Q89 PolarHBondContact O-N 3.43Å; E85-L352 HydrophobicContact CB-CD1 4.35Å; E85-L352 HydrophobicContact CB-CD2 3.77Å; E85-L352 HydrophobicContact CB-CG 3.87Å; E85-L352 HydrophobicContact CG-CD2 4.4Å; E85-L352 HydrophobicContact CG-CG 4.13Å; E85-N435 WeakPolarHBondContact CB-ND2 3.32Å; E85-N435 VanDerWaalsContact CD-CG 3.5Å; E85-N435 WeakPolarHBondContact CG-ND2 3.48Å; E85-N435 WeakPolarHBondContact OE2-CB 3.24Å; E85-N435 PolarHBondContact OE2-ND2 3.47Å
86	S	92.2	Very high	91.7	Very high	0 Å²	0	6.7 Å²	6.7	0%	0	4%	0.035	C	C	.	.	H	α-helix	trans	-59	-42.2	175	170.7	0	0	0	0	112.2	G82 N83 S90 Q249 I253	G82-S86 PolarHBondContact O-N 2.92Å; G82-S86 VanDerWaalsContact O-N 3.13Å; N83-S86 WeakPolarHBondContact O-CB 3.44Å; N83-S86 PolarHBondContact O-N 3.03Å; N83-S86 VanDerWaalsContact O-N 3.15Å; S86-S90 WeakPolarHBondContact O-CB 3.5Å; S86-S90 PolarHBondContact O-N 3.39Å; S86-Q249 PolarHBondContact O-NE2 2.57Å; S86-I253 WeakPolarHBondContact OG-CA 3.46Å
87	D	94.2	Very high	91.8	Very high	1 Å²	1	9.9 Å²	9.9	1%	0.005	5%	0.047	C	C	.	.	H	α-helix	trans	-65.7	-47.6	177.9	-76.8	-22.2	0	0	0	111.3	N83 I84 E85 Q89 S90 G91 L102 N305 V308 V309	N83-D87 WeakPolarHBondContact O-CB 3.39Å; N83-D87 PolarHBondContact O-N 3.33Å; I84-D87 PolarHBondContact O-N 2.88Å; E85-D87 VanDerWaalsContact C-N 3.32Å; E85-D87 PolarHBondContact O-N 3.09Å; D87-Q89 PolarHBondContact O-N 3.39Å; D87-S90 PolarHBondContact O-N 2.94Å; D87-S90 PolarHBondContact O-OG 2.8Å; D87-G91 PolarHBondContact O-N 3.43Å; D87-L102 WeakPolarHBondContact OD1-CD1 3.34Å; D87-N305 WeakPolarHBondContact OD2-CA 3.47Å; D87-N305 WeakPolarHBondContact OD2-CB 3.43Å; D87-N305 PolarHBondContact OD2-ND2 2.86Å; D87-V308 HydrophobicContact CB-CB 4.26Å; D87-V308 HydrophobicContact CB-CG1 3.77Å; D87-V309 HydrophobicContact CB-CG2 3.71Å; D87-V309 WeakPolarHBondContact O-CG2 3.34Å
88	L	93.3	Very high	91.9	Very high	0 Å²	0	10.2 Å²	10.2	0%	0	5%	0.049	C	C	.	.	H	α-helix	trans	-57.3	-46.9	176.3	166.8	163.4	0	0	0	111.5	I84 E85 G91 A92 V308 F312 V350 D351 W371	I84-L88 VanDerWaalsContact O-CB 3.3Å; I84-L88 WeakPolarHBondContact O-CB 3.41Å; I84-L88 PolarHBondContact O-N 3.47Å; E85-L88 PolarHBondContact O-N 3.31Å; L88-G91 PolarHBondContact O-N 3.23Å; L88-A92 PolarHBondContact O-N 2.93Å; L88-V308 HydrophobicContact CB-CG1 4.19Å; L88-F312 HydrophobicContact CB-CB 4.47Å; L88-F312 HydrophobicContact CB-CD2 3.66Å; L88-F312 HydrophobicContact CB-CE2 4.12Å; L88-F312 HydrophobicContact CB-CG 4.1Å; L88-F312 HydrophobicContact CD1-CD1 4.05Å; L88-F312 HydrophobicContact CD1-CD2 3.87Å; L88-F312 HydrophobicContact CD1-CE1 3.89Å; L88-F312 HydrophobicContact CD1-CE2 3.71Å; L88-F312 HydrophobicContact CD1-CG 4.05Å; L88-F312 HydrophobicContact CD1-CZ 3.71Å; L88-F312 HydrophobicContact CG-CB 4.15Å; L88-F312 HydrophobicContact CG-CD1 4.05Å; L88-F312 HydrophobicContact CG-CD2 3.66Å; L88-F312 HydrophobicContact CG-CE1 4.39Å; L88-F312 HydrophobicContact CG-CE2 4.05Å; L88-F312 HydrophobicContact CG-CG 3.67Å; L88-F312 HydrophobicContact CG-CZ 4.39Å; L88-V350 HydrophobicContact CD1-CG1 4.37Å; L88-V350 HydrophobicContact CD2-CB 3.55Å; L88-V350 HydrophobicContact CD2-CG1 3.32Å; L88-V350 HydrophobicContact CG-CG1 4.07Å; L88-D351 WeakPolarHBondContact CD1-O 3.4Å; L88-W371 HydrophobicContact CD1-CH2 4.18Å; L88-W371 HydrophobicContact CD1-CZ2 4.19Å
89	Q	91.9	Very high	92	Very high	5 Å²	5	10.2 Å²	10.2	2%	0.023	5%	0.049	C	C	.	.	H	α-helix	trans	-66	-38.7	177.5	-75.6	174.8	-15.9	0	0	112.1	E85 D87 G91 A92 I93 V350 D436	E85-Q89 WeakPolarHBondContact O-CB 3.27Å; E85-Q89 WeakPolarHBondContact O-CG 3.29Å; E85-Q89 PolarHBondContact O-N 3.43Å; D87-Q89 PolarHBondContact O-N 3.39Å; Q89-G91 VanDerWaalsContact C-N 3.28Å; Q89-G91 PolarHBondContact O-N 3.08Å; Q89-A92 PolarHBondContact O-N 2.87Å; Q89-I93 HydrophobicContact CB-CD1 4.44Å; Q89-I93 WeakPolarHBondContact O-CB 3.5Å; Q89-I93 VanDerWaalsContact O-CG1 3.32Å; Q89-I93 WeakPolarHBondContact O-CG1 3.25Å; Q89-I93 PolarHBondContact O-N 3.37Å; Q89-V350 VanDerWaalsContact CG-O 3.24Å; Q89-V350 WeakPolarHBondContact CG-O 3.48Å; Q89-V350 PolarHBondContact NE2-O 2.92Å; Q89-D436 PolarHBondContact NE2-OD1 2.84Å; Q89-D436 PolarHBondContact OE1-OD1 2.82Å; Q89-D436 VanDerWaalsContact OE1-OD1 3.07Å
90	S	92.2	Very high	92.1	Very high	2 Å²	2	13.2 Å²	13.2	1%	0.014	6%	0.06	C	C	.	.	H	α-helix	trans	-61.9	-38.3	176.2	79.4	0	0	0	0	112.3	S86 D87 A94 N95 V309	S86-S90 WeakPolarHBondContact O-CB 3.5Å; S86-S90 PolarHBondContact O-N 3.39Å; D87-S90 PolarHBondContact O-N 2.94Å; D87-S90 PolarHBondContact O-OG 2.8Å; S90-A94 WeakPolarHBondContact O-CA 3.11Å; S90-A94 WeakPolarHBondContact O-CB 3.12Å; S90-A94 PolarHBondContact O-N 3.05Å; S90-N95 PolarHBondContact O-N 3.2Å; S90-V309 WeakPolarHBondContact OG-CG2 3.36Å
91	G	92.9	Very high	92.1	Very high	0 Å²	0	14.5 Å²	14.5	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-63	-51.9	170.9	0	0	0	0	0	111.4	D87 L88 Q89 I93 N95 V309 G313	D87-G91 PolarHBondContact O-N 3.43Å; L88-G91 PolarHBondContact O-N 3.23Å; Q89-G91 VanDerWaalsContact C-N 3.28Å; Q89-G91 PolarHBondContact O-N 3.08Å; G91-I93 PolarHBondContact O-N 3.15Å; G91-N95 WeakPolarHBondContact O-CA 3.4Å; G91-N95 PolarHBondContact O-N 3.35Å; G91-V309 WeakPolarHBondContact CA-O 3.3Å; G91-G313 VanDerWaalsContact C-CA 3.47Å; G91-G313 VanDerWaalsContact O-CA 3.24Å; G91-G313 WeakPolarHBondContact O-CA 3.45Å
92	A	91.8	Very high	92.3	Very high	11 Å²	11	14.5 Å²	14.5	9%	0.091	7%	0.067	C	C	.	.	H	α-helix	trans	-62	-42.1	-176.8	0	0	0	0	0	113.7	L88 Q89 F316 Y317 V350	L88-A92 PolarHBondContact O-N 2.93Å; Q89-A92 PolarHBondContact O-N 2.87Å; A92-F316 HydrophobicContact CB-CB 3.78Å; A92-Y317 WeakPolarHBondContact O-CA 3.17Å; A92-V350 HydrophobicContact CB-CB 3.98Å; A92-V350 HydrophobicContact CB-CG2 3.37Å
93	I	90.2	Very high	92.5	Very high	52 Å²	52	16 Å²	16	27%	0.267	7%	0.074	S	C	.	.	H	α-helix	trans	-86.6	-41.8	-174.3	-59.7	170.7	0	0	0	111.1	Q89 G91 P245 E246 Y317	Q89-I93 HydrophobicContact CB-CD1 4.44Å; Q89-I93 WeakPolarHBondContact O-CB 3.5Å; Q89-I93 VanDerWaalsContact O-CG1 3.32Å; Q89-I93 WeakPolarHBondContact O-CG1 3.25Å; Q89-I93 PolarHBondContact O-N 3.37Å; G91-I93 PolarHBondContact O-N 3.15Å; I93-P245 HydrophobicContact CG2-CB 3.84Å; I93-E246 HydrophobicContact CG2-CG 4.03Å; I93-Y317 WeakPolarHBondContact O-CE2 3.27Å
94	A	91	Very high	92.4	Very high	0 Å²	0	19.5 Å²	19.5	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-118	4.8	-169.6	0	0	0	0	0	114.5	S90 Y96 R97 L98 E246	S90-A94 WeakPolarHBondContact O-CA 3.11Å; S90-A94 WeakPolarHBondContact O-CB 3.12Å; S90-A94 PolarHBondContact O-N 3.05Å; A94-Y96 PolarHBondContact O-N 3.29Å; A94-Y96 VanDerWaalsContact O-N 3.09Å; A94-R97 HydrophobicContact CB-CB 4.4Å; A94-R97 VanDerWaalsContact O-CB 3.27Å; A94-R97 WeakPolarHBondContact O-CB 3.36Å; A94-R97 VanDerWaalsContact O-CG 3.3Å; A94-R97 WeakPolarHBondContact O-CG 3.48Å; A94-R97 PolarHBondContact O-N 3.4Å; A94-L98 HydrophobicContact CB-CB 4.41Å; A94-L98 HydrophobicContact CB-CD1 3.58Å; A94-L98 HydrophobicContact CB-CG 3.6Å; A94-E246 HydrophobicContact CB-CG 4.08Å
95	N	91.9	Very high	92.4	Very high	37 Å²	37	19.4 Å²	19.4	20%	0.198	9%	0.093	C	C	.	.	T	Hydrogen-bonded Turn	trans	54.4	-111.6	-174.2	-159.4	-0.7	0	0	0	110.7	S90 G91 Y317	S90-N95 PolarHBondContact O-N 3.2Å; G91-N95 WeakPolarHBondContact O-CA 3.4Å; G91-N95 PolarHBondContact O-N 3.35Å; N95-Y317 HydrophobicContact CB-CD1 3.85Å; N95-Y317 HydrophobicContact CB-CD2 3.53Å; N95-Y317 HydrophobicContact CB-CE1 4.06Å; N95-Y317 HydrophobicContact CB-CE2 3.72Å; N95-Y317 HydrophobicContact CB-CG 3.57Å
96	Y	93.5	Very high	92.5	Very high	19 Å²	19	19.6 Å²	19.6	8%	0.075	9%	0.094	C	C	.	.	T	Hydrogen-bonded Turn	trans	-104	1.7	178.5	-48.6	-48.6	0	0	0	113.3	A94 L98 L99 P225 G233	A94-Y96 PolarHBondContact O-N 3.29Å; A94-Y96 VanDerWaalsContact O-N 3.09Å; Y96-L98 VanDerWaalsContact C-N 3.3Å; Y96-L98 PolarHBondContact O-N 3Å; Y96-L99 HydrophobicContact CD1-CD1 4.18Å; Y96-L99 HydrophobicContact CG-CD1 4.35Å; Y96-L99 WeakPolarHBondContact O-CB 3.29Å; Y96-L99 PolarHBondContact O-N 3.33Å; Y96-P225 VanDerWaalsContact OH-CB 3.27Å; Y96-P225 WeakPolarHBondContact OH-CB 3.47Å; Y96-G233 WeakPolarHBondContact O-CA 3.39Å
97	R	91.4	Very high	92.5	Very high	73 Å²	73	24.1 Å²	24.1	28%	0.275	12%	0.118	S	C	.	.	T	Hydrogen-bonded Turn	trans	-71.3	-20.6	-169.5	-62.8	173.5	178.3	174	-1.8	114.1	A94 W100 P240 Y317	A94-R97 HydrophobicContact CB-CB 4.4Å; A94-R97 VanDerWaalsContact O-CB 3.27Å; A94-R97 WeakPolarHBondContact O-CB 3.36Å; A94-R97 VanDerWaalsContact O-CG 3.3Å; A94-R97 WeakPolarHBondContact O-CG 3.48Å; A94-R97 PolarHBondContact O-N 3.4Å; R97-W100 PolarHBondContact O-NE1 3Å; R97-P240 VanDerWaalsContact CZ-O 3.28Å; R97-P240 PolarHBondContact NH1-O 3.45Å; R97-Y317 PolarHBondContact NH2-OH 2.9Å
98	L	92	Very high	92.2	Very high	7 Å²	7	25.7 Å²	25.7	4%	0.037	13%	0.125	C	C	.	.	T	Hydrogen-bonded Turn	trans	-99.7	0.5	178.7	-64.5	177.6	0	0	0	113.4	A94 Y96 W100 L101 L102 Q249 A250 I253	A94-L98 HydrophobicContact CB-CB 4.41Å; A94-L98 HydrophobicContact CB-CD1 3.58Å; A94-L98 HydrophobicContact CB-CG 3.6Å; Y96-L98 VanDerWaalsContact C-N 3.3Å; Y96-L98 PolarHBondContact O-N 3Å; L98-W100 VanDerWaalsContact C-N 3.31Å; L98-W100 PolarHBondContact O-N 2.86Å; L98-L101 WeakPolarHBondContact O-CA 3.41Å; L98-L101 WeakPolarHBondContact O-CB 3.31Å; L98-L101 PolarHBondContact O-N 2.97Å; L98-L102 PolarHBondContact O-N 3.07Å; L98-L102 VanDerWaalsContact O-N 3.11Å; L98-Q249 HydrophobicContact CD1-CB 4.08Å; L98-Q249 HydrophobicContact CD1-CG 4.17Å; L98-A250 HydrophobicContact CD2-CB 3.95Å; L98-I253 HydrophobicContact CB-CD1 3.78Å; L98-I253 HydrophobicContact CD1-CD1 3.89Å; L98-I253 HydrophobicContact CG-CD1 4.4Å
99	L	94.2	Very high	92.1	Very high	1 Å²	1	25.7 Å²	25.7	1%	0.005	13%	0.125	C	C	.	.	H	α-helix	trans	-60.3	-37.1	-178.7	-77.4	176.4	0	0	0	113.2	Y96 L101 L102 L103 L230 L234 I306 V309	Y96-L99 HydrophobicContact CD1-CD1 4.18Å; Y96-L99 HydrophobicContact CG-CD1 4.35Å; Y96-L99 WeakPolarHBondContact O-CB 3.29Å; Y96-L99 PolarHBondContact O-N 3.33Å; L99-L101 PolarHBondContact O-N 3.26Å; L99-L102 HydrophobicContact CD2-CD2 4.21Å; L99-L102 PolarHBondContact O-N 3.18Å; L99-L103 PolarHBondContact O-N 3.28Å; L99-L230 HydrophobicContact CD1-CD2 4.28Å; L99-L230 HydrophobicContact CD1-CG 3.79Å; L99-L234 HydrophobicContact CB-CB 4.38Å; L99-L234 HydrophobicContact CB-CD1 4.18Å; L99-I306 HydrophobicContact CD2-CG1 4.37Å; L99-V309 HydrophobicContact CD2-CB 3.87Å; L99-V309 HydrophobicContact CD2-CG1 3.6Å; L99-V309 HydrophobicContact CD2-CG2 4.19Å; L99-V309 HydrophobicContact CG-CG1 4.15Å
100	W	93.7	Very high	92.2	Very high	65 Å²	65	26.5 Å²	26.5	25%	0.246	13%	0.13	C	C	.	.	H	α-helix	trans	-61.2	-32.8	175.2	69.5	-89.4	0	0	0	111.9	R97 L98 L104 G233 L234 P237	R97-W100 PolarHBondContact O-NE1 3Å; L98-W100 VanDerWaalsContact C-N 3.31Å; L98-W100 PolarHBondContact O-N 2.86Å; W100-L104 HydrophobicContact CE3-CD2 4.33Å; W100-L104 HydrophobicContact CZ3-CD2 3.93Å; W100-L104 WeakPolarHBondContact O-CB 3.43Å; W100-L104 PolarHBondContact O-N 2.95Å; W100-G233 WeakPolarHBondContact CB-O 3.48Å; W100-G233 PolarHBondContact N-O 3.43Å; W100-L234 VanDerWaalsContact CA-O 3.26Å; W100-L234 WeakPolarHBondContact CA-O 3.26Å; W100-L234 WeakPolarHBondContact CB-O 3.48Å; W100-P237 HydrophobicContact CD2-CB 3.77Å; W100-P237 HydrophobicContact CE3-CB 3.78Å; W100-P237 HydrophobicContact CG-CB 4.24Å; W100-P237 HydrophobicContact CH2-CB 4.49Å; W100-P237 HydrophobicContact CZ2-CB 4.49Å; W100-P237 HydrophobicContact CZ3-CB 4.15Å
101	L	91.6	Very high	92.1	Very high	27 Å²	27	29 Å²	29	14%	0.141	14%	0.14	C	C	.	.	H	α-helix	trans	-75	-41.1	178.4	-175.7	63.7	0	0	0	110.7	L98 L99 L104 A105 A250	L98-L101 WeakPolarHBondContact O-CA 3.41Å; L98-L101 WeakPolarHBondContact O-CB 3.31Å; L98-L101 PolarHBondContact O-N 2.97Å; L99-L101 PolarHBondContact O-N 3.26Å; L101-L104 PolarHBondContact O-N 2.89Å; L101-A105 WeakPolarHBondContact O-CB 3.23Å; L101-A105 PolarHBondContact O-N 3.33Å; L101-A250 HydrophobicContact CD2-CB 3.51Å; L101-A250 VanDerWaalsContact CD2-O 3.25Å; L101-A250 WeakPolarHBondContact CD2-O 3.45Å
102	L	93.6	Very high	92	Very high	1 Å²	1	29 Å²	29	1%	0.005	14%	0.14	C	C	.	.	H	α-helix	trans	-58	-46.5	171.7	175	66.5	0	0	0	111.4	D87 L98 L99 A105 T106 I253 V257 L302 N305 V309	D87-L102 WeakPolarHBondContact OD1-CD1 3.34Å; L98-L102 PolarHBondContact O-N 3.07Å; L98-L102 VanDerWaalsContact O-N 3.11Å; L99-L102 HydrophobicContact CD2-CD2 4.21Å; L99-L102 PolarHBondContact O-N 3.18Å; L102-A105 PolarHBondContact O-N 2.86Å; L102-T106 WeakPolarHBondContact O-CB 3.42Å; L102-T106 PolarHBondContact O-N 3.47Å; L102-T106 PolarHBondContact O-OG1 3.45Å; L102-I253 HydrophobicContact CB-CG2 4.25Å; L102-I253 HydrophobicContact CD1-CG2 4.22Å; L102-V257 HydrophobicContact CD1-CG2 3.73Å; L102-L302 HydrophobicContact CG-CD1 4.38Å; L102-N305 HydrophobicContact CD1-CB 4.24Å; L102-N305 HydrophobicContact CD2-CB 3.81Å; L102-N305 HydrophobicContact CG-CB 4.49Å; L102-V309 HydrophobicContact CD2-CG2 3.95Å
103	L	94.7	Very high	92.1	Very high	30 Å²	30	28.5 Å²	28.5	16%	0.157	14%	0.136	C	C	.	.	H	α-helix	trans	-59.6	-49.9	175	175.1	65.7	0	0	0	111	L99 T106 L107 L234 F235 L302	L99-L103 PolarHBondContact O-N 3.28Å; L103-T106 PolarHBondContact O-N 3.23Å; L103-L107 HydrophobicContact CD1-CD1 4.25Å; L103-L107 HydrophobicContact CD1-CG 4.32Å; L103-L107 HydrophobicContact CG-CD1 4.14Å; L103-L107 VanDerWaalsContact O-CG 3.31Å; L103-L107 WeakPolarHBondContact O-CG 3.38Å; L103-L107 PolarHBondContact O-N 3.49Å; L103-L234 HydrophobicContact CB-CD1 3.83Å; L103-L234 HydrophobicContact CD2-CD1 4.11Å; L103-L234 HydrophobicContact CD2-CG 4.07Å; L103-L234 HydrophobicContact CG-CD1 4.41Å; L103-F235 HydrophobicContact CD2-CD1 4.38Å; L103-F235 HydrophobicContact CD2-CE1 4.22Å; L103-L302 HydrophobicContact CD1-CD1 4.42Å; L103-L302 HydrophobicContact CD1-CD2 3.58Å
104	L	91.3	Very high	92.3	Very high	74 Å²	74	30.9 Å²	30.9	39%	0.387	14%	0.142	S	C	.	.	H	α-helix	trans	-62.4	-45.1	-179.1	-179.6	61.8	0	0	0	111.6	W100 L101 T106 L107 M108	W100-L104 HydrophobicContact CE3-CD2 4.33Å; W100-L104 HydrophobicContact CZ3-CD2 3.93Å; W100-L104 WeakPolarHBondContact O-CB 3.43Å; W100-L104 PolarHBondContact O-N 2.95Å; L101-L104 PolarHBondContact O-N 2.89Å; L104-T106 VanDerWaalsContact C-N 3.32Å; L104-T106 PolarHBondContact O-N 3.31Å; L104-L107 PolarHBondContact O-N 2.78Å; L104-M108 HydrophobicContact CD1-CG 4.38Å; L104-M108 HydrophobicContact CD1-SD 3.73Å; L104-M108 HydrophobicContact CD2-SD 4.27Å; L104-M108 HydrophobicContact CG-SD 3.53Å; L104-M108 VanDerWaalsContact CG-SD 3.53Å; L104-M108 WeakPolarHBondContact O-CB 3.23Å; L104-M108 VanDerWaalsContact O-CG 3.22Å; L104-M108 WeakPolarHBondContact O-CG 3.32Å; L104-M108 PolarHBondContact O-N 3.11Å; L104-M108 VanDerWaalsContact O-SD 3.38Å
105	A	90.7	Very high	92.3	Very high	1 Å²	1	31 Å²	31	1%	0.008	14%	0.143	C	C	.	.	H	α-helix	trans	-60.4	-41.2	176	0	0	0	0	0	111.3	L101 L102 M108 G109 L254 V257	L101-A105 WeakPolarHBondContact O-CB 3.23Å; L101-A105 PolarHBondContact O-N 3.33Å; L102-A105 PolarHBondContact O-N 2.86Å; A105-M108 PolarHBondContact O-N 2.98Å; A105-G109 PolarHBondContact O-N 3.46Å; A105-L254 HydrophobicContact CB-CD1 4.1Å; A105-V257 HydrophobicContact CB-CB 4.06Å; A105-V257 HydrophobicContact CB-CG1 3.85Å; A105-V257 HydrophobicContact CB-CG2 4.42Å
106	T	93.5	Very high	92.5	Very high	5 Å²	5	29.3 Å²	29.3	3%	0.031	13%	0.133	C	C	.	.	H	α-helix	trans	-67.3	-41.5	176.9	-56	0	0	0	0	112	L102 L103 L104 M108 G109 L110 L298 L302	L102-T106 WeakPolarHBondContact O-CB 3.42Å; L102-T106 PolarHBondContact O-N 3.47Å; L102-T106 PolarHBondContact O-OG1 3.45Å; L103-T106 PolarHBondContact O-N 3.23Å; L104-T106 VanDerWaalsContact C-N 3.32Å; L104-T106 PolarHBondContact O-N 3.31Å; T106-M108 VanDerWaalsContact C-N 3.35Å; T106-M108 PolarHBondContact O-N 3.44Å; T106-G109 CarbonylContact O-C 3.4Å; T106-G109 WeakPolarHBondContact O-CA 3.37Å; T106-G109 PolarHBondContact O-N 3.44Å; T106-L110 PolarHBondContact O-N 2.96Å; T106-L298 HydrophobicContact CG2-CB 4.44Å; T106-L302 HydrophobicContact CG2-CB 4.2Å; T106-L302 HydrophobicContact CG2-CD1 4.38Å
107	L	92.3	Very high	92.5	Very high	96 Å²	96	28.6 Å²	28.6	50%	0.503	13%	0.131	S	C	.	.	H	α-helix	trans	-64	-39.8	175.2	-70.8	174.5	0	0	0	112	L103 L104 L110 F111	L103-L107 HydrophobicContact CD1-CD1 4.25Å; L103-L107 HydrophobicContact CD1-CG 4.32Å; L103-L107 HydrophobicContact CG-CD1 4.14Å; L103-L107 VanDerWaalsContact O-CG 3.31Å; L103-L107 WeakPolarHBondContact O-CG 3.38Å; L103-L107 PolarHBondContact O-N 3.49Å; L104-L107 PolarHBondContact O-N 2.78Å; L107-L110 PolarHBondContact O-N 2.67Å; L107-F111 WeakPolarHBondContact O-CB 3.38Å; L107-F111 PolarHBondContact O-N 3.02Å
108	M	87.8	Confident	92.6	Very high	33 Å²	33	27.1 Å²	27.1	16%	0.163	13%	0.126	C	C	.	.	H	α-helix	trans	-68.3	-38.8	174.8	-70.6	158.3	70.4	0	0	111.4	L104 A105 T106 F111 L112 V486 I490	L104-M108 HydrophobicContact CD1-CG 4.38Å; L104-M108 HydrophobicContact CD1-SD 3.73Å; L104-M108 HydrophobicContact CD2-SD 4.27Å; L104-M108 HydrophobicContact CG-SD 3.53Å; L104-M108 VanDerWaalsContact CG-SD 3.53Å; L104-M108 WeakPolarHBondContact O-CB 3.23Å; L104-M108 VanDerWaalsContact O-CG 3.22Å; L104-M108 WeakPolarHBondContact O-CG 3.32Å; L104-M108 PolarHBondContact O-N 3.11Å; L104-M108 VanDerWaalsContact O-SD 3.38Å; A105-M108 PolarHBondContact O-N 2.98Å; T106-M108 VanDerWaalsContact C-N 3.35Å; T106-M108 PolarHBondContact O-N 3.44Å; M108-F111 WeakPolarHBondContact O-CB 3.08Å; M108-F111 PolarHBondContact O-N 3.17Å; M108-L112 WeakPolarHBondContact O-CG 3.42Å; M108-L112 PolarHBondContact O-N 3.19Å; M108-V486 HydrophobicContact CE-CG1 4.47Å; M108-V486 HydrophobicContact CG-CG1 4.41Å; M108-I490 HydrophobicContact CB-CD1 4.33Å; M108-I490 HydrophobicContact CE-CB 4.36Å; M108-I490 HydrophobicContact CE-CD1 3.14Å; M108-I490 HydrophobicContact CE-CG1 2.95Å; M108-I490 HydrophobicContact CG-CD1 4.48Å
109	G	91.5	Very high	92.7	Very high	0 Å²	0	26.8 Å²	26.8	0%	0	12%	0.124	C	C	.	.	H	α-helix	trans	-54.4	-56.3	168.4	0	0	0	0	0	111.6	Y78 A105 T106 F111 L112 Q113	Y78-G109 VanDerWaalsContact OH-CA 3.26Å; Y78-G109 WeakPolarHBondContact OH-CA 3.42Å; A105-G109 PolarHBondContact O-N 3.46Å; T106-G109 CarbonylContact O-C 3.4Å; T106-G109 WeakPolarHBondContact O-CA 3.37Å; T106-G109 PolarHBondContact O-N 3.44Å; G109-F111 PolarHBondContact O-N 3.33Å; G109-L112 PolarHBondContact O-N 3.18Å; G109-L112 VanDerWaalsContact O-N 3.12Å; G109-Q113 WeakPolarHBondContact O-CB 3.23Å; G109-Q113 WeakPolarHBondContact O-CG 3.32Å; G109-Q113 PolarHBondContact O-N 2.71Å
110	L	93.6	Very high	92.7	Very high	23 Å²	23	26.7 Å²	26.7	12%	0.12	12%	0.124	C	C	.	.	H	α-helix	trans	-54.6	-42	176.5	175.8	61.9	0	0	0	112	T106 L107 Q113 R114 F291 T295 L298	T106-L110 PolarHBondContact O-N 2.96Å; L107-L110 PolarHBondContact O-N 2.67Å; L110-Q113 PolarHBondContact O-N 3.34Å; L110-R114 WeakPolarHBondContact O-CB 3.48Å; L110-R114 PolarHBondContact O-N 2.9Å; L110-F291 HydrophobicContact CD1-CE2 4.37Å; L110-F291 HydrophobicContact CG-CE2 4.41Å; L110-T295 HydrophobicContact CD2-CG2 4.14Å; L110-L298 VanDerWaalsContact CA-CD1 3.49Å; L110-L298 HydrophobicContact CB-CD1 3.64Å; L110-L298 HydrophobicContact CD1-CD1 3.87Å; L110-L298 HydrophobicContact CG-CD1 4.35Å
111	F	90.3	Very high	92.6	Very high	55 Å²	55	23.7 Å²	23.7	24%	0.241	11%	0.112	C	C	.	.	H	α-helix	trans	-61.9	-49.1	177.3	176.2	-96.7	0	0	0	112.2	L107 M108 G109 R114 L115 V483	L107-F111 WeakPolarHBondContact O-CB 3.38Å; L107-F111 PolarHBondContact O-N 3.02Å; M108-F111 WeakPolarHBondContact O-CB 3.08Å; M108-F111 PolarHBondContact O-N 3.17Å; G109-F111 PolarHBondContact O-N 3.33Å; F111-R114 WeakPolarHBondContact O-CB 3.34Å; F111-R114 PolarHBondContact O-N 3.47Å; F111-L115 HydrophobicContact CE1-CD1 3.71Å; F111-L115 HydrophobicContact CE1-CG 4.26Å; F111-L115 HydrophobicContact CZ-CD1 3.85Å; F111-L115 HydrophobicContact CZ-CD2 4.34Å; F111-L115 HydrophobicContact CZ-CG 4.15Å; F111-L115 PolarHBondContact O-N 2.93Å; F111-V483 HydrophobicContact CE1-CB 4.26Å; F111-V483 HydrophobicContact CE1-CG1 3.72Å; F111-V483 HydrophobicContact CE1-CG2 4.42Å; F111-V483 HydrophobicContact CE2-CG2 3.88Å; F111-V483 HydrophobicContact CZ-CB 3.64Å; F111-V483 HydrophobicContact CZ-CG1 3.37Å; F111-V483 HydrophobicContact CZ-CG2 3.37Å
112	L	91.2	Very high	92.7	Very high	0 Å²	0	23.3 Å²	23.3	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-67.1	-39.3	177.7	-67.5	169.9	0	0	0	111.7	M108 G109 R114 L115 A116 V258 F263 V450 L453 I490	M108-L112 WeakPolarHBondContact O-CG 3.42Å; M108-L112 PolarHBondContact O-N 3.19Å; G109-L112 PolarHBondContact O-N 3.18Å; G109-L112 VanDerWaalsContact O-N 3.12Å; L112-R114 VanDerWaalsContact C-N 3.32Å; L112-R114 PolarHBondContact O-N 2.9Å; L112-L115 WeakPolarHBondContact O-CA 3.34Å; L112-L115 WeakPolarHBondContact O-CB 3.21Å; L112-L115 PolarHBondContact O-N 3.3Å; L112-A116 PolarHBondContact O-N 3.33Å; L112-V258 HydrophobicContact CD1-CG1 3.93Å; L112-F263 HydrophobicContact CB-CD1 4.32Å; L112-F263 HydrophobicContact CB-CE1 3.47Å; L112-F263 VanDerWaalsContact CB-CE1 3.47Å; L112-F263 HydrophobicContact CB-CZ 3.64Å; L112-F263 HydrophobicContact CD1-CE1 4.33Å; L112-F263 HydrophobicContact CD1-CE2 4.35Å; L112-F263 HydrophobicContact CD1-CZ 3.63Å; L112-F263 HydrophobicContact CG-CZ 4.24Å; L112-V450 HydrophobicContact CD1-CG2 3.88Å; L112-V450 HydrophobicContact CD2-CG1 4.1Å; L112-V450 HydrophobicContact CD2-CG2 4.3Å; L112-L453 WeakPolarHBondContact O-CD2 3.24Å; L112-I490 HydrophobicContact CD1-CD1 4.4Å
113	Q	94.8	Very high	92.6	Very high	0 Å²	0	24.6 Å²	24.6	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-63.2	-38	176.2	-70.2	-65.3	0.7	0	0	111.9	M74 G109 L110 L115 A116 A117 N262 F263 H266	M74-Q113 HydrophobicContact CE-CB 4.07Å; M74-Q113 HydrophobicContact CE-CG 4.01Å; M74-Q113 HydrophobicContact CG-CG 4.25Å; M74-Q113 HydrophobicContact SD-CB 4.32Å; M74-Q113 VanDerWaalsContact SD-CD 3.52Å; M74-Q113 HydrophobicContact SD-CG 3.61Å; G109-Q113 WeakPolarHBondContact O-CB 3.23Å; G109-Q113 WeakPolarHBondContact O-CG 3.32Å; G109-Q113 PolarHBondContact O-N 2.71Å; L110-Q113 PolarHBondContact O-N 3.34Å; Q113-L115 VanDerWaalsContact C-N 3.29Å; Q113-L115 PolarHBondContact O-N 2.92Å; Q113-A116 PolarHBondContact O-N 2.94Å; Q113-A117 WeakPolarHBondContact O-CB 3.23Å; Q113-A117 PolarHBondContact O-N 2.85Å; Q113-N262 PolarHBondContact NE2-ND2 2.93Å; Q113-F263 HydrophobicContact CG-CD1 4.45Å; Q113-F263 HydrophobicContact CG-CE1 4.25Å; Q113-H266 PolarHBondContact O-ND1 3.05Å; Q113-H266 VanDerWaalsContact OE1-CB 3.24Å; Q113-H266 PolarHBondContact OE1-ND1 3.32Å
114	R	93.5	Very high	92.4	Very high	102 Å²	102	24 Å²	24	39%	0.385	12%	0.121	S	C	.	.	H	α-helix	trans	-59.8	-40.6	170.5	-177.4	-173	-177.5	-176.7	-1.1	111.5	L110 F111 L112 R118 F291	L110-R114 WeakPolarHBondContact O-CB 3.48Å; L110-R114 PolarHBondContact O-N 2.9Å; F111-R114 WeakPolarHBondContact O-CB 3.34Å; F111-R114 PolarHBondContact O-N 3.47Å; L112-R114 VanDerWaalsContact C-N 3.32Å; L112-R114 PolarHBondContact O-N 2.9Å; R114-R118 HydrophobicContact CG-CG 4.45Å; R114-R118 WeakPolarHBondContact O-CB 3.35Å; R114-R118 WeakPolarHBondContact O-CG 3.17Å; R114-R118 PolarHBondContact O-N 3.45Å; R114-F291 HydrophobicContact CB-CD2 4.17Å; R114-F291 HydrophobicContact CG-CD2 3.82Å; R114-F291 HydrophobicContact CG-CE2 4.42Å
115	L	91.9	Very high	92.4	Very high	3 Å²	3	26.3 Å²	26.3	2%	0.016	13%	0.125	C	C	.	.	H	α-helix	trans	-65.4	-42.5	176.1	-64.8	-173.8	0	0	0	111.5	F111 L112 Q113 R118 L119 L453 L454 T457 N468 V483	F111-L115 HydrophobicContact CE1-CD1 3.71Å; F111-L115 HydrophobicContact CE1-CG 4.26Å; F111-L115 HydrophobicContact CZ-CD1 3.85Å; F111-L115 HydrophobicContact CZ-CD2 4.34Å; F111-L115 HydrophobicContact CZ-CG 4.15Å; F111-L115 PolarHBondContact O-N 2.93Å; L112-L115 WeakPolarHBondContact O-CA 3.34Å; L112-L115 WeakPolarHBondContact O-CB 3.21Å; L112-L115 PolarHBondContact O-N 3.3Å; Q113-L115 VanDerWaalsContact C-N 3.29Å; Q113-L115 PolarHBondContact O-N 2.92Å; L115-R118 PolarHBondContact O-N 3.02Å; L115-L119 PolarHBondContact O-N 3.4Å; L115-L453 HydrophobicContact CB-CD1 4.2Å; L115-L453 HydrophobicContact CB-CD2 4.1Å; L115-L453 HydrophobicContact CB-CG 4.1Å; L115-L454 HydrophobicContact CD1-CD2 3.79Å; L115-T457 HydrophobicContact CB-CG2 4.16Å; L115-T457 WeakPolarHBondContact O-CG2 3.31Å; L115-N468 VanDerWaalsContact CD2-ND2 3.34Å; L115-N468 WeakPolarHBondContact CD2-ND2 3.29Å; L115-V483 HydrophobicContact CD1-CG1 3.91Å
116	A	94.8	Very high	92.6	Very high	0 Å²	0	26.5 Å²	26.5	0%	0	13%	0.125	C	C	.	.	H	α-helix	trans	-62.7	-47.5	178	0	0	0	0	0	111.8	L112 Q113 L119 G120 F263 S267 L453	L112-A116 PolarHBondContact O-N 3.33Å; Q113-A116 PolarHBondContact O-N 2.94Å; A116-L119 PolarHBondContact O-N 2.89Å; A116-G120 PolarHBondContact O-N 2.77Å; A116-F263 HydrophobicContact CB-CB 4.22Å; A116-F263 HydrophobicContact CB-CD1 4.47Å; A116-S267 WeakPolarHBondContact O-CA 3.24Å; A116-S267 WeakPolarHBondContact O-CB 3.44Å; A116-L453 HydrophobicContact CB-CD1 4.11Å; A116-L453 HydrophobicContact CB-CD2 4.2Å
117	A	94.5	Very high	92.6	Very high	4 Å²	4	26.3 Å²	26.3	3%	0.033	12%	0.124	C	C	.	.	H	α-helix	trans	-58.5	-49.1	174.1	0	0	0	0	0	111.5	Q113 L119 G120 V121 V270	Q113-A117 WeakPolarHBondContact O-CB 3.23Å; Q113-A117 PolarHBondContact O-N 2.85Å; A117-L119 VanDerWaalsContact C-N 3.31Å; A117-L119 PolarHBondContact O-N 3.47Å; A117-G120 PolarHBondContact O-N 3.02Å; A117-G120 VanDerWaalsContact O-N 3.14Å; A117-V121 VanDerWaalsContact O-CG2 3.29Å; A117-V121 WeakPolarHBondContact O-CG2 3.39Å; A117-V121 PolarHBondContact O-N 3.18Å; A117-V270 HydrophobicContact CB-CG1 3.93Å
118	R	93.7	Very high	92.8	Very high	42 Å²	42	21.7 Å²	21.7	16%	0.158	10%	0.1	C	C	.	.	H	α-helix	trans	-60.2	-40.2	179.4	-74.6	178.3	76.1	-146.2	-2	112.6	R114 L115 G120 V121 V122 N287 M463 F466 N468	R114-R118 HydrophobicContact CG-CG 4.45Å; R114-R118 WeakPolarHBondContact O-CB 3.35Å; R114-R118 WeakPolarHBondContact O-CG 3.17Å; R114-R118 PolarHBondContact O-N 3.45Å; L115-R118 PolarHBondContact O-N 3.02Å; R118-G120 VanDerWaalsContact C-N 3.34Å; R118-V121 PolarHBondContact O-N 3.1Å; R118-V122 VanDerWaalsContact O-CB 3.31Å; R118-V122 WeakPolarHBondContact O-CB 3.29Å; R118-V122 VanDerWaalsContact O-CG2 3.22Å; R118-V122 WeakPolarHBondContact O-CG2 3.44Å; R118-V122 PolarHBondContact O-N 3.37Å; R118-N287 WeakPolarHBondContact CG-OD1 3.38Å; R118-M463 HydrophobicContact CB-CE 4.17Å; R118-F466 PolarHBondContact NH2-O 2.87Å; R118-N468 PolarHBondContact NH1-OD1 3.45Å
119	L	93.8	Very high	93.1	Very high	0 Å²	0	21.2 Å²	21.2	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-58.3	-48.5	175.5	-176.1	72.1	0	0	0	110.8	L115 A116 A117 S123 L127 L453 F456 T457 I462 M463	L115-L119 PolarHBondContact O-N 3.4Å; A116-L119 PolarHBondContact O-N 2.89Å; A117-L119 VanDerWaalsContact C-N 3.31Å; A117-L119 PolarHBondContact O-N 3.47Å; L119-S123 VanDerWaalsContact O-CB 3.31Å; L119-S123 WeakPolarHBondContact O-CB 3.22Å; L119-S123 PolarHBondContact O-N 3Å; L119-S123 PolarHBondContact O-OG 3.41Å; L119-L127 HydrophobicContact CD2-CB 3.95Å; L119-L127 HydrophobicContact CD2-CD1 3.51Å; L119-L127 HydrophobicContact CD2-CG 4.33Å; L119-L453 HydrophobicContact CD2-CD1 4.24Å; L119-F456 HydrophobicContact CD1-CB 3.88Å; L119-T457 HydrophobicContact CB-CG2 3.94Å; L119-T457 HydrophobicContact CD1-CG2 4.2Å; L119-I462 HydrophobicContact CD1-CG2 3.9Å; L119-M463 HydrophobicContact CD1-SD 4.12Å
120	G	93.7	Very high	93.3	Very high	0 Å²	0	21.5 Å²	21.5	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-63.2	-43.5	179.3	0	0	0	0	0	113.7	A116 A117 R118 G124 R125 S267	A116-G120 PolarHBondContact O-N 2.77Å; A117-G120 PolarHBondContact O-N 3.02Å; A117-G120 VanDerWaalsContact O-N 3.14Å; R118-G120 VanDerWaalsContact C-N 3.34Å; G120-G124 WeakPolarHBondContact O-CA 3.44Å; G120-G124 PolarHBondContact O-N 3.18Å; G120-G124 VanDerWaalsContact O-N 3.1Å; G120-R125 WeakPolarHBondContact CA-O 3.47Å; G120-S267 WeakPolarHBondContact CA-O 3.41Å
121	V	92.6	Very high	93.3	Very high	1 Å²	1	20.4 Å²	20.4	1%	0.006	9%	0.093	C	C	.	.	H	α-helix	trans	-66.6	-51.1	-179.8	174.9	0	0	0	0	111.4	A117 R118 V270 I275 R277 V283 A286 Y290	A117-V121 VanDerWaalsContact O-CG2 3.29Å; A117-V121 WeakPolarHBondContact O-CG2 3.39Å; A117-V121 PolarHBondContact O-N 3.18Å; R118-V121 PolarHBondContact O-N 3.1Å; V121-V270 HydrophobicContact CG2-CB 3.92Å; V121-V270 HydrophobicContact CG2-CG1 4.5Å; V121-V270 HydrophobicContact CG2-CG2 4Å; V121-I275 HydrophobicContact CG1-CD1 4.08Å; V121-R277 PolarHBondContact O-NE 3.28Å; V121-V283 HydrophobicContact CG1-CG1 4.23Å; V121-A286 HydrophobicContact CG1-CB 4.02Å; V121-Y290 HydrophobicContact CG2-CD2 3.52Å; V121-Y290 HydrophobicContact CG2-CE2 3.51Å
122	V	92.8	Very high	93.5	Very high	20 Å²	20	19.5 Å²	19.5	12%	0.121	9%	0.088	C	C	.	.	H	α-helix	trans	-71.5	-50	-173.9	175.6	0	0	0	0	111.2	R118 V283 M463 F466	R118-V122 VanDerWaalsContact O-CB 3.31Å; R118-V122 WeakPolarHBondContact O-CB 3.29Å; R118-V122 VanDerWaalsContact O-CG2 3.22Å; R118-V122 WeakPolarHBondContact O-CG2 3.44Å; R118-V122 PolarHBondContact O-N 3.37Å; V122-V283 HydrophobicContact CG2-CG1 3.75Å; V122-M463 HydrophobicContact CB-CE 4.17Å; V122-M463 HydrophobicContact CB-SD 4.11Å; V122-M463 HydrophobicContact CG1-CE 4.45Å; V122-M463 HydrophobicContact CG1-SD 4.19Å; V122-M463 HydrophobicContact CG2-CE 3.92Å; V122-F466 HydrophobicContact CG1-CB 4.22Å; V122-F466 HydrophobicContact CG1-CD2 3.95Å; V122-F466 HydrophobicContact CG1-CG 4.44Å; V122-F466 HydrophobicContact CG2-CB 3.81Å; V122-F466 HydrophobicContact CG2-CD2 4.03Å; V122-F466 HydrophobicContact CG2-CG 3.93Å
123	S	91.5	Very high	93.6	Very high	28 Å²	28	21.7 Å²	21.7	20%	0.196	10%	0.1	C	C	.	.	H	α-helix	trans	-80.7	-18.8	-174.4	73.2	0	0	0	0	113.4	L119 R125	L119-S123 VanDerWaalsContact O-CB 3.31Å; L119-S123 WeakPolarHBondContact O-CB 3.22Å; L119-S123 PolarHBondContact O-N 3Å; L119-S123 PolarHBondContact O-OG 3.41Å; S123-R125 PolarHBondContact O-N 3.37Å; S123-R125 PolarHBondContact OG-N 3.29Å; S123-R125 VanDerWaalsContact OG-N 3.09Å; S123-R125 PolarHBondContact OG-O 2.83Å
124	G	90.2	Very high	93.4	Very high	17 Å²	17	24.6 Å²	24.6	18%	0.175	11%	0.114	C	C	.	.	S	Bend	trans	66.4	9.9	-169.1	0	0	0	0	0	114.1	G120 K271	G120-G124 WeakPolarHBondContact O-CA 3.44Å; G120-G124 PolarHBondContact O-N 3.18Å; G120-G124 VanDerWaalsContact O-N 3.1Å; G124-K271 WeakPolarHBondContact O-CE 3.35Å
125	R	91.6	Very high	93.4	Very high	123 Å²	123	20.1 Å²	20.1	46%	0.464	10%	0.097	S	C	.	.	S	Bend	trans	-126.4	142.3	-179.3	-63.8	174.8	177.1	-167.3	-7.5	109	G120 S123 E129 V130 D133	G120-R125 WeakPolarHBondContact CA-O 3.47Å; S123-R125 PolarHBondContact O-N 3.37Å; S123-R125 PolarHBondContact OG-N 3.29Å; S123-R125 VanDerWaalsContact OG-N 3.09Å; S123-R125 PolarHBondContact OG-O 2.83Å; R125-E129 WeakPolarHBondContact CA-OE2 3.19Å; R125-E129 HydrophobicContact CB-CB 4.07Å; R125-V130 HydrophobicContact CB-CG2 3.92Å; R125-D133 IonicContact CZ-OD2 3.63Å; R125-D133 IonicContact NH1-OD2 3.52Å; R125-D133 PolarHBondContact NH1-OD2 3.14Å; R125-D133 IonicContact NH2-OD2 3.23Å
126	H	94.1	Very high	93.5	Very high	5 Å²	5	22.7 Å²	22.7	2%	0.023	11%	0.114	C	C	.	.			trans	-83.2	166.3	175.3	61	74.7	0	0	0	110.9	A128 E129 V130 A268 K271 F392	H126-A128 VanDerWaalsContact C-N 3.29Å; H126-A128 PolarHBondContact ND1-N 2.98Å; H126-A128 PolarHBondContact O-N 3.48Å; H126-A128 VanDerWaalsContact O-N 3.16Å; H126-E129 VanDerWaalsContact CD2-CD 3.4Å; H126-E129 IonicContact CD2-OE1 3.61Å; H126-E129 IonicContact CD2-OE2 3.84Å; H126-E129 PolarHBondContact CD2-OE2 3.28Å; H126-E129 VanDerWaalsContact CD2-OE2 3.24Å; H126-E129 VanDerWaalsContact CE1-CG 3.49Å; H126-E129 WeakPolarHBondContact CE1-CG 3.49Å; H126-E129 IonicContact CG-OE2 3.38Å; H126-E129 PolarHBondContact N-OE2 3.11Å; H126-E129 PolarHBondContact ND1-N 3.01Å; H126-E129 VanDerWaalsContact NE2-CD 3.29Å; H126-E129 WeakPolarHBondContact NE2-CG 3.16Å; H126-E129 IonicContact NE2-OE1 3.49Å; H126-E129 IonicContact NE2-OE2 3.67Å; H126-E129 WeakPolarHBondContact O-CB 3.45Å; H126-E129 PolarHBondContact O-N 2.68Å; H126-V130 PolarHBondContact O-N 2.7Å; H126-A268 HydrophobicContact CB-CB 3.66Å; H126-K271 HydrophobicContact CB-CD 4.26Å; H126-F392 PolarHBondContact CE1-O 3.14Å
127	L	95	Very high	93.4	Very high	0 Å²	0	26.7 Å²	26.7	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-53.4	-43.1	-171.2	-179.3	59.1	0	0	0	113.2	L119 V130 C131 F263 Y264 S267 P452 L453 F456	L119-L127 HydrophobicContact CD2-CB 3.95Å; L119-L127 HydrophobicContact CD2-CD1 3.51Å; L119-L127 HydrophobicContact CD2-CG 4.33Å; L127-V130 PolarHBondContact O-N 2.83Å; L127-C131 PolarHBondContact O-N 3.38Å; L127-C131 PolarHBondContact O-SG 2.83Å; L127-C131 VanDerWaalsContact O-SG 3.33Å; L127-F263 HydrophobicContact CD2-CB 4.35Å; L127-Y264 HydrophobicContact CB-CD1 3.84Å; L127-Y264 HydrophobicContact CB-CE1 4.08Å; L127-Y264 HydrophobicContact CD2-CD1 3.91Å; L127-Y264 HydrophobicContact CD2-CE1 3.63Å; L127-Y264 HydrophobicContact CD2-CE2 4.35Å; L127-Y264 HydrophobicContact CD2-CG 4.38Å; L127-Y264 HydrophobicContact CG-CD1 3.9Å; L127-Y264 HydrophobicContact CG-CE1 3.61Å; L127-S267 PolarHBondContact N-OG 3.24Å; L127-P452 HydrophobicContact CD1-CB 4.27Å; L127-L453 HydrophobicContact CD1-CB 4.39Å; L127-L453 HydrophobicContact CD1-CD1 4.45Å; L127-L453 HydrophobicContact CD2-CB 4.18Å; L127-L453 HydrophobicContact CD2-CD1 4.5Å; L127-F456 HydrophobicContact CD1-CD2 3.81Å; L127-F456 HydrophobicContact CD1-CE2 4.31Å
128	A	95.5	Very high	93.4	Very high	0 Å²	0	30.4 Å²	30.4	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-66.8	-34	178.5	0	0	0	0	0	114.2	H126 C131 Y132 Y264 G396 F397	H126-A128 VanDerWaalsContact C-N 3.29Å; H126-A128 PolarHBondContact ND1-N 2.98Å; H126-A128 PolarHBondContact O-N 3.48Å; H126-A128 VanDerWaalsContact O-N 3.16Å; A128-C131 PolarHBondContact O-N 3.43Å; A128-Y132 PolarHBondContact O-N 3.48Å; A128-Y132 VanDerWaalsContact O-N 3.11Å; A128-Y264 HydrophobicContact CB-CD1 3.86Å; A128-Y264 HydrophobicContact CB-CE1 4.24Å; A128-G396 CarbonylContact O-C 3.6Å; A128-F397 HydrophobicContact CB-CD2 3.61Å; A128-F397 HydrophobicContact CB-CE2 3.66Å; A128-F397 HydrophobicContact CB-CG 4.24Å; A128-F397 HydrophobicContact CB-CZ 4.37Å
129	E	95.3	Very high	93.5	Very high	23 Å²	23	28.6 Å²	28.6	11%	0.107	16%	0.156	C	C	.	.	H	α-helix	trans	-65.5	-40.9	173.6	-80	165.6	154.3	0	0	110.9	R125 H126 Y132 D133 K271	R125-E129 WeakPolarHBondContact CA-OE2 3.19Å; R125-E129 HydrophobicContact CB-CB 4.07Å; H126-E129 VanDerWaalsContact CD2-CD 3.4Å; H126-E129 IonicContact CD2-OE1 3.61Å; H126-E129 IonicContact CD2-OE2 3.84Å; H126-E129 PolarHBondContact CD2-OE2 3.28Å; H126-E129 VanDerWaalsContact CD2-OE2 3.24Å; H126-E129 VanDerWaalsContact CE1-CG 3.49Å; H126-E129 WeakPolarHBondContact CE1-CG 3.49Å; H126-E129 IonicContact CG-OE2 3.38Å; H126-E129 PolarHBondContact N-OE2 3.11Å; H126-E129 PolarHBondContact ND1-N 3.01Å; H126-E129 VanDerWaalsContact NE2-CD 3.29Å; H126-E129 WeakPolarHBondContact NE2-CG 3.16Å; H126-E129 IonicContact NE2-OE1 3.49Å; H126-E129 IonicContact NE2-OE2 3.67Å; H126-E129 WeakPolarHBondContact O-CB 3.45Å; H126-E129 PolarHBondContact O-N 2.68Å; E129-Y132 WeakPolarHBondContact O-CB 3.35Å; E129-Y132 PolarHBondContact O-N 2.91Å; E129-D133 PolarHBondContact O-N 2.96Å; E129-K271 IonicContact OE1-NZ 2.96Å; E129-K271 PolarHBondContact OE1-NZ 3.38Å; E129-K271 IonicContact OE2-NZ 2.78Å; E129-K271 PolarHBondContact OE2-NZ 2.86Å
130	V	94.1	Very high	93.5	Very high	5 Å²	5	29.8 Å²	29.8	3%	0.03	16%	0.161	C	C	.	.	H	α-helix	trans	-66.5	-43.6	176.6	-177.7	0	0	0	0	110.6	R125 H126 L127 Y132 D133 E134 F456 I462	R125-V130 HydrophobicContact CB-CG2 3.92Å; H126-V130 PolarHBondContact O-N 2.7Å; L127-V130 PolarHBondContact O-N 2.83Å; V130-Y132 PolarHBondContact O-N 2.86Å; V130-D133 PolarHBondContact O-N 3.38Å; V130-D133 VanDerWaalsContact O-N 3.15Å; V130-E134 HydrophobicContact CG1-CG 4.14Å; V130-E134 WeakPolarHBondContact O-CG 3.46Å; V130-E134 PolarHBondContact O-N 3.44Å; V130-F456 HydrophobicContact CB-CD2 4.13Å; V130-F456 HydrophobicContact CB-CE2 4.33Å; V130-F456 HydrophobicContact CG1-CB 4.05Å; V130-F456 HydrophobicContact CG1-CD1 3.87Å; V130-F456 HydrophobicContact CG1-CD2 3.51Å; V130-F456 HydrophobicContact CG1-CE1 4.18Å; V130-F456 HydrophobicContact CG1-CE2 3.82Å; V130-F456 HydrophobicContact CG1-CG 3.53Å; V130-F456 HydrophobicContact CG1-CZ 4.14Å; V130-I462 HydrophobicContact CG1-CD1 3.71Å
131	C	94.6	Very high	93.6	Very high	0 Å²	0	33.5 Å²	33.5	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-54.6	-35.5	172.4	-72.4	0	0	0	0	112.3	L127 A128 Y135 F397 F456	L127-C131 PolarHBondContact O-N 3.38Å; L127-C131 PolarHBondContact O-SG 2.83Å; L127-C131 VanDerWaalsContact O-SG 3.33Å; A128-C131 PolarHBondContact O-N 3.43Å; C131-Y135 HydrophobicContact CB-CD2 4.09Å; C131-Y135 WeakPolarHBondContact O-CB 3.34Å; C131-Y135 PolarHBondContact O-N 3Å; C131-F397 HydrophobicContact CB-CD1 3.82Å; C131-F397 HydrophobicContact CB-CE1 3.3Å; C131-F397 HydrophobicContact CB-CZ 3.98Å; C131-F456 HydrophobicContact CB-CE2 4.48Å
132	Y	94.5	Very high	93.7	Very high	36 Å²	36	36.9 Å²	36.9	14%	0.141	20%	0.197	C	C	.	.	H	α-helix	trans	-68.9	-36.2	-179.7	-178.6	-73.9	0	0	0	114.5	R36 A128 E129 V130 R140 G396 F397 N399	R36-Y132 VanDerWaalsContact NH1-CD1 3.3Å; A128-Y132 PolarHBondContact O-N 3.48Å; A128-Y132 VanDerWaalsContact O-N 3.11Å; E129-Y132 WeakPolarHBondContact O-CB 3.35Å; E129-Y132 PolarHBondContact O-N 2.91Å; V130-Y132 PolarHBondContact O-N 2.86Å; Y132-R140 VanDerWaalsContact CA-CD 3.45Å; Y132-R140 VanDerWaalsContact CZ-NH1 3.32Å; Y132-R140 PolarHBondContact O-NH1 3.28Å; Y132-G396 WeakPolarHBondContact CB-O 3.41Å; Y132-G396 WeakPolarHBondContact CD2-O 3.48Å; Y132-F397 VanDerWaalsContact CD2-O 3.27Å; Y132-F397 WeakPolarHBondContact CD2-O 3.33Å; Y132-N399 HydrophobicContact CE2-CB 3.81Å
133	D	92.3	Very high	93.8	Very high	47 Å²	47	36 Å²	36	25%	0.251	19%	0.192	S	C	.	.	H	α-helix	trans	-82.6	-30.2	-178.4	-75	-25.1	0	0	0	112.3	R33 R36 R125 E129 V130	R33-D133 IonicContact NH1-OD1 3.95Å; R33-D133 PolarHBondContact NH1-OD1 2.89Å; R33-D133 VanDerWaalsContact NH1-OD1 3.12Å; R36-D133 IonicContact CZ-OD1 2.66Å; R36-D133 IonicContact NH2-OD1 2.76Å; R36-D133 PolarHBondContact NH2-OD1 3.17Å; R36-D133 IonicContact NH2-OD2 3.79Å; R36-D133 PolarHBondContact NH2-OD2 3.39Å; R125-D133 IonicContact CZ-OD2 3.63Å; R125-D133 IonicContact NH1-OD2 3.52Å; R125-D133 PolarHBondContact NH1-OD2 3.14Å; R125-D133 IonicContact NH2-OD2 3.23Å; E129-D133 PolarHBondContact O-N 2.96Å; V130-D133 PolarHBondContact O-N 3.38Å; V130-D133 VanDerWaalsContact O-N 3.15Å
134	E	92.5	Very high	94	Very high	61 Å²	61	37.5 Å²	37.5	29%	0.285	19%	0.193	S	C	.	.	H	α-helix	trans	-95.6	-42.7	-174.7	-59.4	-60.5	165.9	0	0	114.1	V130 F456 I462 F537 H541	V130-E134 HydrophobicContact CG1-CG 4.14Å; V130-E134 WeakPolarHBondContact O-CG 3.46Å; V130-E134 PolarHBondContact O-N 3.44Å; E134-F456 HydrophobicContact CB-CE1 3.57Å; E134-F456 HydrophobicContact CB-CZ 3.82Å; E134-F456 HydrophobicContact CG-CD1 4.25Å; E134-F456 HydrophobicContact CG-CE1 3.65Å; E134-F456 HydrophobicContact CG-CZ 4.16Å; E134-I462 HydrophobicContact CG-CD1 4.2Å; E134-F537 VanDerWaalsContact O-CZ 3.29Å; E134-F537 WeakPolarHBondContact O-CZ 3.45Å; E134-H541 VanDerWaalsContact CD-NE2 3.29Å; E134-H541 IonicContact OE1-NE2 2.9Å; E134-H541 IonicContact OE2-CD2 3.92Å; E134-H541 PolarHBondContact OE2-CD2 3.17Å; E134-H541 IonicContact OE2-CE1 2.7Å; E134-H541 IonicContact OE2-NE2 3.12Å; E134-H541 PolarHBondContact OE2-NE2 3.13Å
135	Y	92.9	Very high	94.2	Very high	8 Å²	8	41 Å²	41	3%	0.031	21%	0.207	C	C	.	.	S	Bend	trans	-82.7	144.5	-177.2	-74.8	-71.8	0	0	0	112.4	C131 A139 L143 P452 F456 L534 F537	C131-Y135 HydrophobicContact CB-CD2 4.09Å; C131-Y135 WeakPolarHBondContact O-CB 3.34Å; C131-Y135 PolarHBondContact O-N 3Å; Y135-A139 HydrophobicContact CD1-CB 4.33Å; Y135-L143 HydrophobicContact CD2-CD1 3.78Å; Y135-L143 HydrophobicContact CE2-CD1 3.74Å; Y135-L143 HydrophobicContact CG-CD1 4.29Å; Y135-P452 HydrophobicContact CE2-CB 4.15Å; Y135-P452 HydrophobicContact CE2-CG 4.18Å; Y135-F456 AromaticContact CD2-CZ 3.89Å; Y135-F456 HydrophobicContact CD2-CZ 3.89Å; Y135-F456 HydrophobicContact CE2-CE1 4.44Å; Y135-F456 AromaticContact CE2-CE2 4Å; Y135-F456 HydrophobicContact CE2-CE2 4Å; Y135-F456 AromaticContact CE2-CZ 3.46Å; Y135-F456 HydrophobicContact CE2-CZ 3.46Å; Y135-F456 VanDerWaalsContact CE2-CZ 3.46Å; Y135-L534 HydrophobicContact CD1-CD2 4.39Å; Y135-L534 HydrophobicContact CE1-CD2 3.63Å; Y135-F537 AromaticContact CD1-CD1 3.68Å; Y135-F537 HydrophobicContact CD1-CD1 3.68Å; Y135-F537 HydrophobicContact CD1-CD2 4.23Å; Y135-F537 AromaticContact CD1-CE1 3.62Å; Y135-F537 HydrophobicContact CD1-CE1 3.62Å; Y135-F537 HydrophobicContact CD1-CE2 4.19Å; Y135-F537 AromaticContact CD1-CG 4Å; Y135-F537 HydrophobicContact CD1-CG 4Å; Y135-F537 AromaticContact CD1-CZ 3.9Å; Y135-F537 HydrophobicContact CD1-CZ 3.9Å; Y135-F537 HydrophobicContact CE1-CB 4.19Å; Y135-F537 AromaticContact CE1-CD1 3.11Å; Y135-F537 HydrophobicContact CE1-CD1 3.11Å; Y135-F537 HydrophobicContact CE1-CD2 4.3Å; Y135-F537 AromaticContact CE1-CE1 3.45Å; Y135-F537 HydrophobicContact CE1-CE1 3.45Å; Y135-F537 VanDerWaalsContact CE1-CE1 3.45Å; Y135-F537 AromaticContact CE1-CG 3.61Å; Y135-F537 HydrophobicContact CE1-CG 3.61Å; Y135-F537 HydrophobicContact CE1-CZ 4.19Å; Y135-F537 HydrophobicContact CG-CE1 4.33Å; Y135-F537 AromaticContact CZ-CD1 3.8Å
136	P	93.6	Very high	94.4	Very high	56 Å²	56	37.2 Å²	37.2	36%	0.364	20%	0.195	S	C	.	.			trans	-64.7	156.6	170.6	29.6	-34.7	0	0	0	110.9	P138 A139 R140 Y533	P136-P138 VanDerWaalsContact C-CD 3.42Å; P136-A139 HydrophobicContact CG-CB 4.1Å; P136-A139 PolarHBondContact O-N 3.24Å; P136-R140 WeakPolarHBondContact O-CB 3.5Å; P136-R140 PolarHBondContact O-N 3.21Å; P136-Y533 VanDerWaalsContact CG-OH 3.24Å; P136-Y533 WeakPolarHBondContact CG-OH 3.31Å
137	T	93.4	Very high	94.3	Very high	84 Å²	84	37.1 Å²	37.1	52%	0.515	20%	0.195	S	C	.	.	H	α-helix	trans	-53.1	-40.5	-172.5	48.9	0	0	0	0	114.9	I141	T137-I141 WeakPolarHBondContact O-CD1 3.31Å; T137-I141 VanDerWaalsContact O-CG1 3.25Å; T137-I141 WeakPolarHBondContact O-CG1 3.27Å; T137-I141 PolarHBondContact O-N 3.01Å; T137-I141 VanDerWaalsContact O-N 3.09Å
138	P	94.6	Very high	94.3	Very high	82 Å²	82	38.1 Å²	38.1	53%	0.532	20%	0.2	S	C	.	.	H	α-helix	trans	-67.6	-47.7	-179.5	-18.2	33.5	0	0	0	112	P136 R140 I141 I142	P136-P138 VanDerWaalsContact C-CD 3.42Å; P138-R140 VanDerWaalsContact C-N 3.29Å; P138-R140 PolarHBondContact O-N 3.5Å; P138-I141 PolarHBondContact O-N 3.38Å; P138-I142 WeakPolarHBondContact O-CG1 3.39Å; P138-I142 PolarHBondContact O-N 2.85Å
139	A	94	Very high	94.2	Very high	5 Å²	5	40.5 Å²	40.5	4%	0.041	22%	0.215	C	C	.	.	H	α-helix	trans	-61.9	-40	179.9	0	0	0	0	0	111.7	Y135 P136 I142 L143 F530 Y533	Y135-A139 HydrophobicContact CD1-CB 4.33Å; P136-A139 HydrophobicContact CG-CB 4.1Å; P136-A139 PolarHBondContact O-N 3.24Å; A139-I142 PolarHBondContact O-N 3.16Å; A139-L143 WeakPolarHBondContact O-CB 3.39Å; A139-L143 WeakPolarHBondContact O-CG 3.41Å; A139-L143 PolarHBondContact O-N 2.88Å; A139-F530 HydrophobicContact CB-CE2 4.28Å; A139-Y533 HydrophobicContact CB-CD1 4.49Å; A139-Y533 HydrophobicContact CB-CE1 3.52Å
140	R	94.7	Very high	94.1	Very high	24 Å²	24	39.5 Å²	39.5	9%	0.091	21%	0.21	C	C	.	.	H	α-helix	trans	-62.2	-43.3	176.6	-172.9	-174.7	70.5	-168.1	11.9	112.8	Y132 P136 P138 L143 W144 F397	Y132-R140 VanDerWaalsContact CA-CD 3.45Å; Y132-R140 VanDerWaalsContact CZ-NH1 3.32Å; Y132-R140 PolarHBondContact O-NH1 3.28Å; P136-R140 WeakPolarHBondContact O-CB 3.5Å; P136-R140 PolarHBondContact O-N 3.21Å; P138-R140 VanDerWaalsContact C-N 3.29Å; P138-R140 PolarHBondContact O-N 3.5Å; R140-L143 PolarHBondContact O-N 3.2Å; R140-W144 PolarHBondContact O-N 2.9Å; R140-F397 WeakPolarHBondContact CD-O 3.41Å; R140-F397 HydrophobicContact CG-CB 4.33Å; R140-F397 HydrophobicContact CG-CD1 3.65Å; R140-F397 HydrophobicContact CG-CG 4.5Å; R140-F397 PolarHBondContact NE-O 3.07Å
141	I	95.7	Very high	94.1	Very high	79 Å²	79	39.4 Å²	39.4	41%	0.405	21%	0.209	S	C	.	.	H	α-helix	trans	-68.4	-41.5	179.2	-68.8	166.2	0	0	0	110.6	T137 P138 W144 L145 L398	T137-I141 WeakPolarHBondContact O-CD1 3.31Å; T137-I141 VanDerWaalsContact O-CG1 3.25Å; T137-I141 WeakPolarHBondContact O-CG1 3.27Å; T137-I141 PolarHBondContact O-N 3.01Å; T137-I141 VanDerWaalsContact O-N 3.09Å; P138-I141 PolarHBondContact O-N 3.38Å; I141-W144 PolarHBondContact O-N 3.09Å; I141-L145 PolarHBondContact O-N 3.03Å; I141-L398 HydrophobicContact CG1-CD2 4.23Å
142	I	95.3	Very high	94	Very high	72 Å²	72	41 Å²	41	37%	0.369	22%	0.218	S	C	.	.	H	α-helix	trans	-63.6	-44.8	176.2	-62	166.4	0	0	0	110.2	P138 A139 W144 L145 M146 F530	P138-I142 WeakPolarHBondContact O-CG1 3.39Å; P138-I142 PolarHBondContact O-N 2.85Å; A139-I142 PolarHBondContact O-N 3.16Å; I142-W144 VanDerWaalsContact C-N 3.34Å; I142-W144 PolarHBondContact O-N 3.22Å; I142-L145 PolarHBondContact O-N 2.89Å; I142-M146 HydrophobicContact CG2-CE 4.25Å; I142-M146 WeakPolarHBondContact O-CG 3.27Å; I142-M146 PolarHBondContact O-N 2.99Å; I142-F530 HydrophobicContact CB-CE1 4.08Å; I142-F530 HydrophobicContact CB-CE2 4.14Å; I142-F530 HydrophobicContact CB-CZ 3.71Å; I142-F530 HydrophobicContact CD1-CE2 4.24Å; I142-F530 HydrophobicContact CG2-CD1 3.76Å; I142-F530 HydrophobicContact CG2-CD2 4.36Å; I142-F530 HydrophobicContact CG2-CE1 3.39Å; I142-F530 HydrophobicContact CG2-CE2 4.03Å; I142-F530 HydrophobicContact CG2-CG 4.24Å; I142-F530 HydrophobicContact CG2-CZ 3.54Å
143	L	94.5	Very high	93.9	Very high	0 Å²	0	39.5 Å²	39.5	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-57.7	-45.1	174.2	-82.3	175.5	0	0	0	112.1	Y135 A139 R140 L145 M146 V147 F397 F448 P452 F530 L534	Y135-L143 HydrophobicContact CD2-CD1 3.78Å; Y135-L143 HydrophobicContact CE2-CD1 3.74Å; Y135-L143 HydrophobicContact CG-CD1 4.29Å; A139-L143 WeakPolarHBondContact O-CB 3.39Å; A139-L143 WeakPolarHBondContact O-CG 3.41Å; A139-L143 PolarHBondContact O-N 2.88Å; R140-L143 PolarHBondContact O-N 3.2Å; L143-L145 VanDerWaalsContact C-N 3.34Å; L143-L145 PolarHBondContact O-N 3.05Å; L143-M146 PolarHBondContact O-N 3.18Å; L143-V147 WeakPolarHBondContact O-CG2 3.26Å; L143-V147 PolarHBondContact O-N 3.19Å; L143-F397 HydrophobicContact CB-CD1 4.47Å; L143-F397 HydrophobicContact CB-CE1 3.7Å; L143-F397 HydrophobicContact CB-CZ 4.13Å; L143-F397 HydrophobicContact CD1-CE1 4.28Å; L143-F448 HydrophobicContact CD2-CB 3.94Å; L143-F448 HydrophobicContact CD2-CD1 4.25Å; L143-F448 HydrophobicContact CD2-CG 4.49Å; L143-F448 WeakPolarHBondContact CD2-O 3.22Å; L143-P452 HydrophobicContact CD1-CG 4.25Å; L143-P452 HydrophobicContact CD2-CG 4.39Å; L143-F530 HydrophobicContact CD2-CE1 4.06Å; L143-F530 HydrophobicContact CD2-CZ 4.26Å; L143-F530 HydrophobicContact CG-CE1 4.21Å; L143-F530 HydrophobicContact CG-CZ 3.95Å; L143-L534 HydrophobicContact CD1-CD2 3.96Å; L143-L534 HydrophobicContact CD2-CD1 3.68Å; L143-L534 HydrophobicContact CD2-CD2 4.21Å; L143-L534 HydrophobicContact CG-CD2 4.22Å
144	W	95.6	Very high	93.8	Very high	60 Å²	60	37.3 Å²	37.3	23%	0.227	20%	0.201	C	C	.	.	H	α-helix	trans	-58.5	-46.2	176.1	170.7	68.6	0	0	0	111.9	R140 I141 I142 M146 V147 E148 F397 L398	R140-W144 PolarHBondContact O-N 2.9Å; I141-W144 PolarHBondContact O-N 3.09Å; I142-W144 VanDerWaalsContact C-N 3.34Å; I142-W144 PolarHBondContact O-N 3.22Å; W144-M146 VanDerWaalsContact C-N 3.31Å; W144-M146 PolarHBondContact O-N 3.1Å; W144-V147 PolarHBondContact O-N 2.65Å; W144-V147 VanDerWaalsContact O-N 3.17Å; W144-E148 HydrophobicContact CD2-CG 4.12Å; W144-E148 VanDerWaalsContact CE2-CG 3.47Å; W144-E148 HydrophobicContact CG-CG 4.43Å; W144-E148 HydrophobicContact CZ2-CG 3.71Å; W144-E148 VanDerWaalsContact NE1-CG 3.34Å; W144-E148 PolarHBondContact NE1-OE1 3.43Å; W144-E148 WeakPolarHBondContact O-CG 3.29Å; W144-E148 PolarHBondContact O-N 3.03Å; W144-F397 HydrophobicContact CB-CB 3.64Å; W144-F397 HydrophobicContact CB-CD1 4.27Å; W144-F397 HydrophobicContact CB-CD2 4.07Å; W144-F397 HydrophobicContact CB-CG 3.79Å; W144-F397 HydrophobicContact CG-CB 3.99Å; W144-F397 HydrophobicContact CG-CG 4.44Å; W144-L398 HydrophobicContact CD2-CD1 3.67Å; W144-L398 HydrophobicContact CD2-CD2 4.23Å; W144-L398 HydrophobicContact CD2-CG 3.96Å; W144-L398 VanDerWaalsContact CE2-CD1 3.46Å; W144-L398 HydrophobicContact CE3-CD1 3.96Å; W144-L398 HydrophobicContact CE3-CD2 4.31Å; W144-L398 HydrophobicContact CE3-CG 4.43Å; W144-L398 HydrophobicContact CG-CD1 4.33Å; W144-L398 HydrophobicContact CG-CD2 4.4Å; W144-L398 HydrophobicContact CG-CG 4.12Å; W144-L398 HydrophobicContact CH2-CD1 3.86Å; W144-L398 HydrophobicContact CZ2-CD1 3.57Å; W144-L398 HydrophobicContact CZ3-CD1 4.04Å
145	L	95.2	Very high	93.8	Very high	91 Å²	91	35 Å²	35	48%	0.476	19%	0.191	S	C	.	.	H	α-helix	trans	-60.2	-41.5	178.2	-175.1	144.1	0	0	0	111.7	I141 I142 L143 E148 V149	I141-L145 PolarHBondContact O-N 3.03Å; I142-L145 PolarHBondContact O-N 2.89Å; L143-L145 VanDerWaalsContact C-N 3.34Å; L143-L145 PolarHBondContact O-N 3.05Å; L145-E148 PolarHBondContact O-N 3.1Å; L145-V149 HydrophobicContact CD2-CG2 4.27Å; L145-V149 VanDerWaalsContact O-CG2 3.29Å; L145-V149 WeakPolarHBondContact O-CG2 3.45Å; L145-V149 PolarHBondContact O-N 3.31Å
146	M	94.2	Very high	93.7	Very high	43 Å²	43	35.5 Å²	35.5	21%	0.212	19%	0.194	C	C	.	.	H	α-helix	trans	-62.9	-41	175.8	-67.1	-56.7	168	0	0	112.4	I142 L143 W144 V149 A150 Q445 F448	I142-M146 HydrophobicContact CG2-CE 4.25Å; I142-M146 WeakPolarHBondContact O-CG 3.27Å; I142-M146 PolarHBondContact O-N 2.99Å; L143-M146 PolarHBondContact O-N 3.18Å; W144-M146 VanDerWaalsContact C-N 3.31Å; W144-M146 PolarHBondContact O-N 3.1Å; M146-V149 PolarHBondContact O-N 2.98Å; M146-A150 PolarHBondContact O-N 3.11Å; M146-A150 VanDerWaalsContact O-N 3.07Å; M146-Q445 PolarHBondContact O-OE1 2.96Å; M146-F448 HydrophobicContact CB-CB 4.21Å; M146-F448 HydrophobicContact CB-CD2 3.67Å; M146-F448 HydrophobicContact CB-CE2 4.24Å; M146-F448 HydrophobicContact CB-CG 3.99Å; M146-F448 HydrophobicContact CG-CD1 4.5Å; M146-F448 HydrophobicContact CG-CD2 3.7Å; M146-F448 HydrophobicContact CG-CE2 3.77Å; M146-F448 HydrophobicContact CG-CG 4.08Å; M146-F448 HydrophobicContact CG-CZ 4.24Å; M146-F448 HydrophobicContact SD-CD2 4.21Å; M146-F448 HydrophobicContact SD-CE2 3.79Å; M146-F448 HydrophobicContact SD-CZ 4.34Å
147	V	93.6	Very high	93.6	Very high	4 Å²	4	32.9 Å²	32.9	2%	0.024	18%	0.176	C	C	.	.	H	α-helix	trans	-67.5	-41.1	176.4	175.9	0	0	0	0	111.7	L143 W144 V149 A150 I151 Y264 A393 F397	L143-V147 WeakPolarHBondContact O-CG2 3.26Å; L143-V147 PolarHBondContact O-N 3.19Å; W144-V147 PolarHBondContact O-N 2.65Å; W144-V147 VanDerWaalsContact O-N 3.17Å; V147-V149 VanDerWaalsContact C-N 3.34Å; V147-V149 PolarHBondContact O-N 3.26Å; V147-A150 WeakPolarHBondContact O-CB 3.38Å; V147-A150 PolarHBondContact O-N 2.96Å; V147-I151 HydrophobicContact CG1-CD1 3.97Å; V147-I151 WeakPolarHBondContact O-CG1 3.29Å; V147-I151 PolarHBondContact O-N 3.16Å; V147-Y264 HydrophobicContact CB-CE2 4.41Å; V147-Y264 HydrophobicContact CG1-CD2 4.01Å; V147-Y264 HydrophobicContact CG1-CE2 3.99Å; V147-Y264 HydrophobicContact CG2-CD2 4.29Å; V147-Y264 HydrophobicContact CG2-CE1 4.44Å; V147-Y264 HydrophobicContact CG2-CE2 3.44Å; V147-Y264 VanDerWaalsContact CG2-CE2 3.44Å; V147-Y264 WeakPolarHBondContact CG2-OH 3.02Å; V147-A393 HydrophobicContact CG1-CB 3.92Å; V147-F397 HydrophobicContact CG2-CE2 4.16Å; V147-F397 HydrophobicContact CG2-CZ 4.39Å
148	E	94.2	Very high	93.5	Very high	21 Å²	21	29 Å²	29	10%	0.098	15%	0.152	C	C	.	.	H	α-helix	trans	-63.8	-38.4	175	-68.6	-67.7	171.6	0	0	111.8	W144 L145 A150 I151 I152 R407	W144-E148 HydrophobicContact CD2-CG 4.12Å; W144-E148 VanDerWaalsContact CE2-CG 3.47Å; W144-E148 HydrophobicContact CG-CG 4.43Å; W144-E148 HydrophobicContact CZ2-CG 3.71Å; W144-E148 VanDerWaalsContact NE1-CG 3.34Å; W144-E148 PolarHBondContact NE1-OE1 3.43Å; W144-E148 WeakPolarHBondContact O-CG 3.29Å; W144-E148 PolarHBondContact O-N 3.03Å; L145-E148 PolarHBondContact O-N 3.1Å; E148-A150 VanDerWaalsContact C-N 3.32Å; E148-A150 PolarHBondContact O-N 3.22Å; E148-I151 PolarHBondContact O-N 3.26Å; E148-I152 VanDerWaalsContact O-CG1 3.32Å; E148-I152 WeakPolarHBondContact O-CG1 3.45Å; E148-I152 PolarHBondContact O-N 2.94Å; E148-R407 IonicContact OE1-CZ 3.03Å; E148-R407 IonicContact OE1-NH1 2.65Å; E148-R407 IonicContact OE1-NH2 2.78Å; E148-R407 PolarHBondContact OE1-NH2 3.44Å; E148-R407 IonicContact OE2-NH2 3.93Å; E148-R407 PolarHBondContact OE2-NH2 3.17Å
149	V	93.5	Very high	93.3	Very high	50 Å²	50	25 Å²	25	30%	0.303	13%	0.127	S	C	.	.	H	α-helix	trans	-60.4	-42.3	172.8	169	0	0	0	0	111	L145 M146 V147 I151 I152 G153 L441	L145-V149 HydrophobicContact CD2-CG2 4.27Å; L145-V149 VanDerWaalsContact O-CG2 3.29Å; L145-V149 WeakPolarHBondContact O-CG2 3.45Å; L145-V149 PolarHBondContact O-N 3.31Å; M146-V149 PolarHBondContact O-N 2.98Å; V147-V149 VanDerWaalsContact C-N 3.34Å; V147-V149 PolarHBondContact O-N 3.26Å; V149-I151 VanDerWaalsContact C-N 3.34Å; V149-I151 PolarHBondContact O-N 2.94Å; V149-I152 PolarHBondContact O-N 3.39Å; V149-G153 PolarHBondContact O-N 3.04Å; V149-L441 HydrophobicContact CG1-CD1 4.36Å; V149-L441 HydrophobicContact CG1-CD2 4.18Å
150	A	93.4	Very high	93.1	Very high	1 Å²	1	24.9 Å²	24.9	1%	0.008	13%	0.125	C	C	.	.	H	α-helix	trans	-64.9	-36.3	175.8	0	0	0	0	0	112.8	M146 V147 E148 S154 M442 Q445	M146-A150 PolarHBondContact O-N 3.11Å; M146-A150 VanDerWaalsContact O-N 3.07Å; V147-A150 WeakPolarHBondContact O-CB 3.38Å; V147-A150 PolarHBondContact O-N 2.96Å; E148-A150 VanDerWaalsContact C-N 3.32Å; E148-A150 PolarHBondContact O-N 3.22Å; A150-S154 PolarHBondContact O-N 3.04Å; A150-S154 VanDerWaalsContact O-N 3.14Å; A150-M442 HydrophobicContact CB-SD 4.02Å; A150-Q445 HydrophobicContact CB-CB 4.03Å; A150-Q445 HydrophobicContact CB-CG 4.06Å
151	I	93.2	Very high	93	Very high	4 Å²	4	23.8 Å²	23.8	2%	0.021	12%	0.121	C	C	.	.	H	α-helix	trans	-68.1	-47.9	176.3	-67.8	158.7	0	0	0	110.5	V147 E148 V149 G153 S154 D155 H261	V147-I151 HydrophobicContact CG1-CD1 3.97Å; V147-I151 WeakPolarHBondContact O-CG1 3.29Å; V147-I151 PolarHBondContact O-N 3.16Å; E148-I151 PolarHBondContact O-N 3.26Å; V149-I151 VanDerWaalsContact C-N 3.34Å; V149-I151 PolarHBondContact O-N 2.94Å; I151-G153 VanDerWaalsContact C-N 3.27Å; I151-G153 PolarHBondContact O-N 3.36Å; I151-S154 PolarHBondContact O-N 2.83Å; I151-D155 WeakPolarHBondContact O-CB 3.09Å; I151-D155 PolarHBondContact O-N 2.95Å; I151-H261 HydrophobicContact CG1-CB 3.68Å
152	I	93.1	Very high	92.8	Very high	34 Å²	34	20 Å²	20	17%	0.174	10%	0.102	C	C	.	.	H	α-helix	trans	-60.8	-40.2	177.5	-67.7	163.1	0	0	0	110.4	E148 V149 D155 M156 I414 A415	E148-I152 VanDerWaalsContact O-CG1 3.32Å; E148-I152 WeakPolarHBondContact O-CG1 3.45Å; E148-I152 PolarHBondContact O-N 2.94Å; V149-I152 PolarHBondContact O-N 3.39Å; I152-D155 WeakPolarHBondContact O-CB 3.27Å; I152-D155 PolarHBondContact O-N 2.71Å; I152-M156 HydrophobicContact CG2-SD 4.47Å; I152-M156 WeakPolarHBondContact O-CG 3.5Å; I152-M156 PolarHBondContact O-N 3.03Å; I152-I414 HydrophobicContact CD1-CG2 3.95Å; I152-I414 HydrophobicContact CG2-CG2 4.09Å; I152-A415 HydrophobicContact CG2-CB 4.32Å
153	G	92	Very high	92.6	Very high	3 Å²	3	16.7 Å²	16.7	3%	0.031	9%	0.085	C	C	.	.	H	α-helix	trans	-59.7	-46.2	176.3	0	0	0	0	0	112.6	V149 I151 M156 Q157	V149-G153 PolarHBondContact O-N 3.04Å; I151-G153 VanDerWaalsContact C-N 3.27Å; I151-G153 PolarHBondContact O-N 3.36Å; G153-M156 WeakPolarHBondContact O-CB 3.19Å; G153-M156 PolarHBondContact O-N 3.37Å; G153-Q157 WeakPolarHBondContact O-CG 3.18Å; G153-Q157 PolarHBondContact O-N 3.02Å
154	S	91.6	Very high	92.3	Very high	2 Å²	2	16.9 Å²	16.9	1%	0.014	9%	0.086	C	C	.	.	H	α-helix	trans	-65.7	-40.1	175.5	179	0	0	0	0	112.7	A150 I151 M156 Q157 E158 M259 H261	A150-S154 PolarHBondContact O-N 3.04Å; A150-S154 VanDerWaalsContact O-N 3.14Å; I151-S154 PolarHBondContact O-N 2.83Å; S154-M156 VanDerWaalsContact C-N 3.27Å; S154-M156 PolarHBondContact O-N 2.7Å; S154-Q157 PolarHBondContact O-N 3.27Å; S154-Q157 VanDerWaalsContact O-N 3.15Å; S154-E158 PolarHBondContact O-N 2.82Å; S154-E158 VanDerWaalsContact O-N 3.1Å; S154-M259 WeakPolarHBondContact OG-CE 3.37Å; S154-H261 PolarHBondContact OG-CE1 2.92Å
155	D	91.7	Very high	92.2	Very high	13 Å²	13	14 Å²	14	7%	0.07	8%	0.075	C	C	.	.	H	α-helix	trans	-59.8	-36.4	175	-166	3	0	0	0	111.1	I151 I152 E158 V159 R412 A415	I151-D155 WeakPolarHBondContact O-CB 3.09Å; I151-D155 PolarHBondContact O-N 2.95Å; I152-D155 WeakPolarHBondContact O-CB 3.27Å; I152-D155 PolarHBondContact O-N 2.71Å; D155-E158 WeakPolarHBondContact O-CB 3.27Å; D155-E158 PolarHBondContact O-N 3.21Å; D155-V159 VanDerWaalsContact O-CG2 3.29Å; D155-V159 WeakPolarHBondContact O-CG2 3.39Å; D155-V159 PolarHBondContact O-N 2.95Å; D155-R412 WeakPolarHBondContact OD1-CD 3.35Å; D155-R412 IonicContact OD1-CZ 2.85Å; D155-R412 IonicContact OD1-NE 3.89Å; D155-R412 IonicContact OD1-NH1 3.51Å; D155-R412 PolarHBondContact OD1-NH1 2.91Å; D155-R412 WeakPolarHBondContact OD2-CA 3.38Å; D155-R412 PolarHBondContact OD2-N 2.89Å; D155-A415 HydrophobicContact CB-CB 3.9Å
156	M	91.2	Very high	92.1	Very high	18 Å²	18	10.8 Å²	10.8	9%	0.089	6%	0.058	C	C	.	.	H	α-helix	trans	-63.5	-44.3	173.6	-71.3	174.8	62.7	0	0	112.8	I152 G153 S154 E158 V159 I160 A415 P418 M434 L438	I152-M156 HydrophobicContact CG2-SD 4.47Å; I152-M156 WeakPolarHBondContact O-CG 3.5Å; I152-M156 PolarHBondContact O-N 3.03Å; G153-M156 WeakPolarHBondContact O-CB 3.19Å; G153-M156 PolarHBondContact O-N 3.37Å; S154-M156 VanDerWaalsContact C-N 3.27Å; S154-M156 PolarHBondContact O-N 2.7Å; M156-E158 VanDerWaalsContact C-N 3.25Å; M156-E158 PolarHBondContact O-N 3Å; M156-V159 PolarHBondContact O-N 3.16Å; M156-I160 VanDerWaalsContact O-CG1 3.3Å; M156-I160 WeakPolarHBondContact O-CG1 2.98Å; M156-I160 PolarHBondContact O-N 3.07Å; M156-A415 HydrophobicContact CG-CB 3.81Å; M156-A415 WeakPolarHBondContact CG-O 3.45Å; M156-P418 HydrophobicContact CE-CB 3.66Å; M156-P418 HydrophobicContact CE-CG 4.23Å; M156-P418 HydrophobicContact SD-CB 4.4Å; M156-P418 HydrophobicContact SD-CG 4.33Å; M156-M434 HydrophobicContact CE-CE 4Å; M156-M434 HydrophobicContact CE-CG 4.19Å; M156-M434 HydrophobicContact CE-SD 3.57Å; M156-M434 VanDerWaalsContact CE-SD 3.57Å; M156-L438 HydrophobicContact CB-CD1 3.66Å; M156-L438 HydrophobicContact CE-CD1 4.18Å; M156-L438 HydrophobicContact CE-CD2 4.25Å; M156-L438 HydrophobicContact SD-CD2 4.08Å
157	Q	91.6	Very high	91.9	Very high	1 Å²	1	9.3 Å²	9.3	1%	0.005	5%	0.051	C	C	.	.	H	α-helix	trans	-62.5	-37.9	178.4	-57.2	-179.4	-70.1	0	0	111	G153 S154 I160 G161 N435 L438 N439	G153-Q157 WeakPolarHBondContact O-CG 3.18Å; G153-Q157 PolarHBondContact O-N 3.02Å; S154-Q157 PolarHBondContact O-N 3.27Å; S154-Q157 VanDerWaalsContact O-N 3.15Å; Q157-I160 PolarHBondContact O-N 2.83Å; Q157-G161 PolarHBondContact O-N 2.81Å; Q157-N435 WeakPolarHBondContact CG-OD1 3.41Å; Q157-N435 PolarHBondContact NE2-OD1 3.48Å; Q157-L438 HydrophobicContact CG-CB 3.91Å; Q157-L438 HydrophobicContact CG-CD1 3.6Å; Q157-L438 HydrophobicContact CG-CG 4.39Å; Q157-N439 PolarHBondContact NE2-OD1 2.67Å
158	E	90.3	Very high	91.8	Very high	1 Å²	1	9.1 Å²	9.1	1%	0.005	5%	0.05	C	C	.	.	H	α-helix	trans	-65.9	-44.1	175.4	-169.1	-148	130.3	0	0	113.4	S154 D155 M156 I160 G161 T162 G379 T383 R412	S154-E158 PolarHBondContact O-N 2.82Å; S154-E158 VanDerWaalsContact O-N 3.1Å; D155-E158 WeakPolarHBondContact O-CB 3.27Å; D155-E158 PolarHBondContact O-N 3.21Å; M156-E158 VanDerWaalsContact C-N 3.25Å; M156-E158 PolarHBondContact O-N 3Å; E158-I160 VanDerWaalsContact C-N 3.27Å; E158-I160 PolarHBondContact O-N 3.49Å; E158-G161 PolarHBondContact O-N 3.27Å; E158-T162 VanDerWaalsContact O-CB 3.3Å; E158-T162 WeakPolarHBondContact O-CB 3.18Å; E158-T162 PolarHBondContact O-N 3.45Å; E158-T162 PolarHBondContact O-OG1 3.43Å; E158-G379 VanDerWaalsContact CG-C 3.44Å; E158-G379 WeakPolarHBondContact CG-O 3.35Å; E158-T383 VanDerWaalsContact CD-N 3.3Å; E158-T383 WeakPolarHBondContact OE1-CB 3.34Å; E158-T383 PolarHBondContact OE1-OG1 2.66Å; E158-T383 WeakPolarHBondContact OE2-CA 3.49Å; E158-T383 WeakPolarHBondContact OE2-CB 3.37Å; E158-T383 PolarHBondContact OE2-N 2.64Å; E158-T383 PolarHBondContact OE2-OG1 3.12Å; E158-R412 IonicContact OE1-CZ 3.24Å; E158-R412 VanDerWaalsContact OE1-CZ 3.23Å; E158-R412 IonicContact OE1-NH1 2.76Å; E158-R412 PolarHBondContact OE1-NH1 2.83Å; E158-R412 IonicContact OE1-NH2 3.21Å; E158-R412 PolarHBondContact OE1-NH2 2.9Å; E158-R412 IonicContact OE2-NH1 3.82Å; E158-R412 PolarHBondContact OE2-NH1 2.84Å
159	V	91.6	Very high	91.7	Very high	0 Å²	0	11 Å²	11	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-59.1	-43	174.8	169.2	0	0	0	0	110	D155 M156 A163 V180 T183 R412 I416 T419	D155-V159 VanDerWaalsContact O-CG2 3.29Å; D155-V159 WeakPolarHBondContact O-CG2 3.39Å; D155-V159 PolarHBondContact O-N 2.95Å; M156-V159 PolarHBondContact O-N 3.16Å; V159-A163 WeakPolarHBondContact O-CB 3.36Å; V159-A163 PolarHBondContact O-N 2.67Å; V159-V180 HydrophobicContact CG1-CB 4.31Å; V159-V180 HydrophobicContact CG1-CG1 3.72Å; V159-V180 HydrophobicContact CG1-CG2 4.16Å; V159-T183 HydrophobicContact CG1-CG2 4.4Å; V159-R412 VanDerWaalsContact CG2-CZ 3.48Å; V159-I416 HydrophobicContact CG1-CG1 4.09Å; V159-I416 HydrophobicContact CG2-CG1 3.89Å; V159-T419 HydrophobicContact CG1-CG2 4Å
160	I	89.8	Confident	91.6	Very high	2 Å²	2	9.7 Å²	9.7	1%	0.01	5%	0.053	C	C	.	.	H	α-helix	trans	-60.7	-54.2	175.6	-64.7	158.4	0	0	0	110.2	M156 Q157 E158 T162 A163 I164 T419 L431 M434 N435 L438	M156-I160 VanDerWaalsContact O-CG1 3.3Å; M156-I160 WeakPolarHBondContact O-CG1 2.98Å; M156-I160 PolarHBondContact O-N 3.07Å; Q157-I160 PolarHBondContact O-N 2.83Å; E158-I160 VanDerWaalsContact C-N 3.27Å; E158-I160 PolarHBondContact O-N 3.49Å; I160-T162 PolarHBondContact O-N 3.48Å; I160-A163 PolarHBondContact O-N 2.78Å; I160-I164 HydrophobicContact CG2-CD1 3.74Å; I160-I164 HydrophobicContact CG2-CG1 4.46Å; I160-I164 WeakPolarHBondContact O-CG1 3.38Å; I160-I164 PolarHBondContact O-N 3.21Å; I160-T419 HydrophobicContact CG1-CG2 4.05Å; I160-L431 HydrophobicContact CG1-CD2 4.24Å; I160-L431 HydrophobicContact CG2-CB 4.46Å; I160-L431 HydrophobicContact CG2-CD1 4.42Å; I160-M434 HydrophobicContact CD1-CE 3.45Å; I160-M434 VanDerWaalsContact CD1-CE 3.45Å; I160-M434 HydrophobicContact CG1-CE 3.83Å; I160-N435 HydrophobicContact CD1-CB 4.5Å; I160-L438 HydrophobicContact CD1-CD1 4.45Å
161	G	91.4	Very high	91.3	Very high	0 Å²	0	11.6 Å²	11.6	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-59.4	-44.4	-177.9	0	0	0	0	0	113.1	Q157 E158 I164 A165	Q157-G161 PolarHBondContact O-N 2.81Å; E158-G161 PolarHBondContact O-N 3.27Å; G161-I164 PolarHBondContact O-N 3.32Å; G161-A165 WeakPolarHBondContact O-CB 3.38Å; G161-A165 PolarHBondContact O-N 2.78Å
162	T	91.1	Very high	90.8	Very high	1 Å²	1	12.5 Å²	12.5	1%	0.006	8%	0.075	C	C	.	.	H	α-helix	trans	-65.2	-40.9	176.8	-59	0	0	0	0	111.6	E158 I160 A165 I166 T183 L376	E158-T162 VanDerWaalsContact O-CB 3.3Å; E158-T162 WeakPolarHBondContact O-CB 3.18Å; E158-T162 PolarHBondContact O-N 3.45Å; E158-T162 PolarHBondContact O-OG1 3.43Å; I160-T162 PolarHBondContact O-N 3.48Å; T162-A165 WeakPolarHBondContact O-CB 3.37Å; T162-A165 PolarHBondContact O-N 2.84Å; T162-I166 HydrophobicContact CG2-CD1 3.94Å; T162-I166 VanDerWaalsContact O-CG1 3.29Å; T162-I166 WeakPolarHBondContact O-CG1 3.21Å; T162-I166 PolarHBondContact O-N 3.25Å; T162-T183 HydrophobicContact CG2-CG2 3.63Å; T162-L376 HydrophobicContact CG2-CD1 3.77Å
163	A	91.1	Very high	90.6	Very high	1 Å²	1	18.6 Å²	18.6	1%	0.008	10%	0.097	C	C	.	.	H	α-helix	trans	-64.3	-42	176.9	0	0	0	0	0	112	V159 I160 I166 N167 L176 V180	V159-A163 WeakPolarHBondContact O-CB 3.36Å; V159-A163 PolarHBondContact O-N 2.67Å; I160-A163 PolarHBondContact O-N 2.78Å; A163-I166 PolarHBondContact O-N 2.9Å; A163-N167 PolarHBondContact O-N 3.35Å; A163-L176 WeakPolarHBondContact O-CD2 3.34Å; A163-V180 HydrophobicContact CB-CB 4.44Å; A163-V180 HydrophobicContact CB-CG2 3.6Å
164	I	90.1	Very high	90.4	Very high	4 Å²	4	21 Å²	21	2%	0.021	11%	0.108	C	C	.	.	H	α-helix	trans	-62.5	-45.3	174.6	-70.3	172.9	0	0	0	110.6	I160 G161 I166 N167 L168 L176 L352 Y353 L375	I160-I164 HydrophobicContact CG2-CD1 3.74Å; I160-I164 HydrophobicContact CG2-CG1 4.46Å; I160-I164 WeakPolarHBondContact O-CG1 3.38Å; I160-I164 PolarHBondContact O-N 3.21Å; G161-I164 PolarHBondContact O-N 3.32Å; I164-I166 PolarHBondContact O-N 3.49Å; I164-N167 PolarHBondContact O-N 2.81Å; I164-L168 HydrophobicContact CG2-CD1 4.04Å; I164-L168 HydrophobicContact CG2-CG 4.43Å; I164-L168 WeakPolarHBondContact O-CG 3.19Å; I164-L168 PolarHBondContact O-N 2.8Å; I164-L176 HydrophobicContact CB-CD2 4.33Å; I164-L176 HydrophobicContact CG1-CD2 3.79Å; I164-L352 HydrophobicContact CD1-CB 3.87Å; I164-L352 HydrophobicContact CD1-CD1 4.47Å; I164-L352 HydrophobicContact CG2-CB 4.21Å; I164-Y353 HydrophobicContact CG2-CD2 4.24Å; I164-L375 HydrophobicContact CG2-CD1 4.16Å
165	A	92.4	Very high	90.2	Very high	0 Å²	0	23.2 Å²	23.2	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-57.5	-47.6	175.9	0	0	0	0	0	112.4	G161 T162 N167 L168 L169 A372 L375 L376	G161-A165 WeakPolarHBondContact O-CB 3.38Å; G161-A165 PolarHBondContact O-N 2.78Å; T162-A165 WeakPolarHBondContact O-CB 3.37Å; T162-A165 PolarHBondContact O-N 2.84Å; A165-N167 VanDerWaalsContact C-N 3.33Å; A165-N167 PolarHBondContact O-N 3.09Å; A165-L168 PolarHBondContact O-N 3.46Å; A165-L169 WeakPolarHBondContact O-CB 3.36Å; A165-L169 VanDerWaalsContact O-CG 3.24Å; A165-L169 WeakPolarHBondContact O-CG 3.38Å; A165-L169 PolarHBondContact O-N 2.86Å; A165-A372 VanDerWaalsContact CB-O 3.25Å; A165-A372 WeakPolarHBondContact CB-O 3.21Å; A165-L375 HydrophobicContact CB-CB 3.9Å; A165-L376 HydrophobicContact CB-CB 3.85Å
166	I	92.6	Very high	89.9	Confident	24 Å²	24	22.9 Å²	22.9	12%	0.123	12%	0.121	C	C	.	.	H	α-helix	trans	-62	-40.9	177.4	-68.8	165.6	0	0	0	111	T162 A163 I164 S170 I174 I182	T162-I166 HydrophobicContact CG2-CD1 3.94Å; T162-I166 VanDerWaalsContact O-CG1 3.29Å; T162-I166 WeakPolarHBondContact O-CG1 3.21Å; T162-I166 PolarHBondContact O-N 3.25Å; A163-I166 PolarHBondContact O-N 2.9Å; I164-I166 PolarHBondContact O-N 3.49Å; I166-S170 VanDerWaalsContact O-CB 3.22Å; I166-S170 WeakPolarHBondContact O-CB 3.17Å; I166-S170 PolarHBondContact O-N 2.9Å; I166-S170 PolarHBondContact O-OG 3.25Å; I166-I174 HydrophobicContact CG2-CB 4.21Å; I166-I174 HydrophobicContact CG2-CD1 3.73Å; I166-I174 HydrophobicContact CG2-CG2 3.97Å; I166-I182 HydrophobicContact CD1-CB 4.15Å; I166-I182 HydrophobicContact CD1-CG2 3.76Å; I166-I182 HydrophobicContact CG2-CD1 4.26Å
167	N	90.9	Very high	89.7	Confident	12 Å²	12	28.3 Å²	28.3	6%	0.064	14%	0.141	C	C	.	.	H	α-helix	trans	-62.5	-46.2	176.3	-177.9	-80.5	0	0	0	111.6	A163 I164 A165 S170 V171 G172 I174 L176 Y353	A163-N167 PolarHBondContact O-N 3.35Å; I164-N167 PolarHBondContact O-N 2.81Å; A165-N167 VanDerWaalsContact C-N 3.33Å; A165-N167 PolarHBondContact O-N 3.09Å; N167-S170 CarbonylContact O-C 3.54Å; N167-S170 PolarHBondContact O-N 3.13Å; N167-S170 PolarHBondContact O-OG 3.04Å; N167-S170 VanDerWaalsContact O-OG 3.06Å; N167-V171 PolarHBondContact O-N 3.33Å; N167-G172 WeakPolarHBondContact O-CA 3.2Å; N167-G172 PolarHBondContact O-N 2.91Å; N167-I174 PolarHBondContact ND2-O 3.32Å; N167-L176 HydrophobicContact CB-CD2 3.58Å; N167-L176 HydrophobicContact CB-CG 4.35Å; N167-Y353 WeakPolarHBondContact OD1-CE2 3.3Å
168	L	91.1	Very high	89.6	Confident	0 Å²	0	29.1 Å²	29.1	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-65.4	-46.3	178.8	-69.9	176.3	0	0	0	112.3	I164 A165 S170 V171 F338 Y353 I357 L368 A372	I164-L168 HydrophobicContact CG2-CD1 4.04Å; I164-L168 HydrophobicContact CG2-CG 4.43Å; I164-L168 WeakPolarHBondContact O-CG 3.19Å; I164-L168 PolarHBondContact O-N 2.8Å; A165-L168 PolarHBondContact O-N 3.46Å; L168-S170 VanDerWaalsContact C-N 3.27Å; L168-S170 PolarHBondContact O-N 3.1Å; L168-V171 PolarHBondContact O-N 3.17Å; L168-F338 HydrophobicContact CD2-CD1 4.18Å; L168-F338 HydrophobicContact CD2-CE1 3.96Å; L168-Y353 HydrophobicContact CD2-CD2 3.77Å; L168-Y353 HydrophobicContact CD2-CE2 3.45Å; L168-Y353 VanDerWaalsContact CD2-CE2 3.45Å; L168-Y353 HydrophobicContact CG-CD2 4.11Å; L168-Y353 HydrophobicContact CG-CE2 4.11Å; L168-I357 HydrophobicContact CD2-CD1 3.76Å; L168-L368 HydrophobicContact CB-CD2 4.23Å; L168-L368 HydrophobicContact CD2-CD2 4.36Å; L168-A372 HydrophobicContact CB-CB 3.65Å; L168-A372 HydrophobicContact CD1-CB 4.24Å
169	L	92.8	Very high	89.6	Confident	61 Å²	61	29 Å²	29	32%	0.319	15%	0.147	S	C	.	.	H	α-helix	trans	-62.2	-34.7	177.3	-72.1	169.7	0	0	0	112.5	A165 V171 F369 A372 I373 L376	A165-L169 WeakPolarHBondContact O-CB 3.36Å; A165-L169 VanDerWaalsContact O-CG 3.24Å; A165-L169 WeakPolarHBondContact O-CG 3.38Å; A165-L169 PolarHBondContact O-N 2.86Å; L169-V171 PolarHBondContact O-N 3.46Å; L169-F369 HydrophobicContact CD2-CD1 4.16Å; L169-A372 HydrophobicContact CD2-CB 3.96Å; L169-A372 HydrophobicContact CG-CB 3.78Å; L169-I373 HydrophobicContact CD2-CG1 3.92Å; L169-L376 HydrophobicContact CD1-CD2 3.91Å
170	S	91.8	Very high	89.5	Confident	22 Å²	22	29 Å²	29	15%	0.154	15%	0.147	C	C	.	.	T	Hydrogen-bonded Turn	trans	-84.7	13.1	176.1	68.2	0	0	0	0	113.3	I166 N167 L168 G172 Y173 I174	I166-S170 VanDerWaalsContact O-CB 3.22Å; I166-S170 WeakPolarHBondContact O-CB 3.17Å; I166-S170 PolarHBondContact O-N 2.9Å; I166-S170 PolarHBondContact O-OG 3.25Å; N167-S170 CarbonylContact O-C 3.54Å; N167-S170 PolarHBondContact O-N 3.13Å; N167-S170 PolarHBondContact O-OG 3.04Å; N167-S170 VanDerWaalsContact O-OG 3.06Å; L168-S170 VanDerWaalsContact C-N 3.27Å; L168-S170 PolarHBondContact O-N 3.1Å; S170-G172 PolarHBondContact O-N 3.12Å; S170-G172 VanDerWaalsContact O-N 3.07Å; S170-Y173 VanDerWaalsContact O-CB 3.29Å; S170-Y173 WeakPolarHBondContact O-CB 3.31Å; S170-Y173 WeakPolarHBondContact O-CD2 3.4Å; S170-Y173 PolarHBondContact O-N 3.32Å; S170-I174 WeakPolarHBondContact OG-CB 3.28Å; S170-I174 PolarHBondContact OG-N 3.04Å; S170-I174 VanDerWaalsContact OG-N 3.13Å
171	V	86.6	Confident	89.5	Confident	41 Å²	41	32.6 Å²	32.6	25%	0.248	17%	0.165	C	C	.	.	T	Hydrogen-bonded Turn	trans	54.7	32	179.6	-160.2	0	0	0	0	112.7	N167 L168 L169 Y173 P335 F338 F369	N167-V171 PolarHBondContact O-N 3.33Å; L168-V171 PolarHBondContact O-N 3.17Å; L169-V171 PolarHBondContact O-N 3.46Å; V171-Y173 VanDerWaalsContact C-N 3.28Å; V171-Y173 HydrophobicContact CB-CD2 4.34Å; V171-Y173 HydrophobicContact CB-CE2 4.45Å; V171-Y173 PolarHBondContact O-N 3.47Å; V171-P335 HydrophobicContact CG1-CB 4.14Å; V171-P335 HydrophobicContact CG1-CG 4.02Å; V171-F338 VanDerWaalsContact CA-CZ 3.46Å; V171-F338 HydrophobicContact CB-CZ 4.13Å; V171-F338 HydrophobicContact CG1-CE2 3.76Å; V171-F338 HydrophobicContact CG1-CZ 3.84Å; V171-F369 HydrophobicContact CG2-CE1 4.4Å; V171-F369 HydrophobicContact CG2-CZ 4.18Å
172	G	83.1	Confident	89.5	Confident	22 Å²	22	35.5 Å²	35.5	23%	0.227	18%	0.18	C	C	.	.	T	Hydrogen-bonded Turn	trans	71.3	11.8	-175.6	0	0	0	0	0	115.3	N167 S170	N167-G172 WeakPolarHBondContact O-CA 3.2Å; N167-G172 PolarHBondContact O-N 2.91Å; S170-G172 PolarHBondContact O-N 3.12Å; S170-G172 VanDerWaalsContact O-N 3.07Å
173	Y	87	Confident	89.4	Confident	163 Å²	163	35.5 Å²	35.5	64%	0.639	18%	0.18	S	C	*	.	S	Bend	trans	-67.2	-36.7	172.6	-78.3	-76	0	0	0	111.9	S170 V171 P175	S170-Y173 VanDerWaalsContact O-CB 3.29Å; S170-Y173 WeakPolarHBondContact O-CB 3.31Å; S170-Y173 WeakPolarHBondContact O-CD2 3.4Å; S170-Y173 PolarHBondContact O-N 3.32Å; V171-Y173 VanDerWaalsContact C-N 3.28Å; V171-Y173 HydrophobicContact CB-CD2 4.34Å; V171-Y173 HydrophobicContact CB-CE2 4.45Å; V171-Y173 PolarHBondContact O-N 3.47Å; Y173-P175 WeakPolarHBondContact O-CD 3.23Å
174	I	88.7	Confident	89.2	Confident	52 Å²	52	38.5 Å²	38.5	27%	0.267	20%	0.195	S	C	.	.	S	Bend	trans	-95.1	111.3	177.5	-58.5	173.4	0	0	0	108.2	I166 N167 S170 A178 I182	I166-I174 HydrophobicContact CG2-CB 4.21Å; I166-I174 HydrophobicContact CG2-CD1 3.73Å; I166-I174 HydrophobicContact CG2-CG2 3.97Å; N167-I174 PolarHBondContact ND2-O 3.32Å; S170-I174 WeakPolarHBondContact OG-CB 3.28Å; S170-I174 PolarHBondContact OG-N 3.04Å; S170-I174 VanDerWaalsContact OG-N 3.13Å; I174-A178 HydrophobicContact CG2-CB 3.84Å; I174-I182 HydrophobicContact CD1-CD1 4.15Å; I174-I182 HydrophobicContact CG2-CD1 3.82Å
175	P	86.6	Confident	88.9	Confident	50 Å²	50	43.5 Å²	43.5	33%	0.325	22%	0.222	S	C	.	.			trans	-66.1	156.6	177.6	29.3	-35.3	0	0	0	111.1	Y173 W177 A178 G179	Y173-P175 WeakPolarHBondContact O-CD 3.23Å; P175-W177 VanDerWaalsContact C-N 3.35Å; P175-W177 HydrophobicContact CG-CD2 4.34Å; P175-W177 HydrophobicContact CG-CZ2 3.84Å; P175-W177 VanDerWaalsContact CG-NE1 3.32Å; P175-W177 PolarHBondContact O-N 3.12Å; P175-A178 HydrophobicContact CG-CB 3.82Å; P175-A178 WeakPolarHBondContact O-CA 3.47Å; P175-A178 WeakPolarHBondContact O-CB 3.49Å; P175-A178 PolarHBondContact O-N 3.38Å; P175-G179 PolarHBondContact O-N 2.83Å
176	L	85.5	Confident	88.3	Confident	5 Å²	5	44.3 Å²	44.3	3%	0.026	23%	0.226	C	C	.	.	H	α-helix	trans	-58.8	-40.2	-173.5	-71.2	176.9	0	0	0	114	A163 I164 N167 A178 G179 V180 I428 L431	A163-L176 WeakPolarHBondContact O-CD2 3.34Å; I164-L176 HydrophobicContact CB-CD2 4.33Å; I164-L176 HydrophobicContact CG1-CD2 3.79Å; N167-L176 HydrophobicContact CB-CD2 3.58Å; N167-L176 HydrophobicContact CB-CG 4.35Å; L176-A178 PolarHBondContact O-N 3.22Å; L176-G179 CarbonylContact O-C 3.56Å; L176-G179 WeakPolarHBondContact O-CA 3.32Å; L176-G179 PolarHBondContact O-N 2.94Å; L176-V180 WeakPolarHBondContact O-CG2 3.32Å; L176-V180 PolarHBondContact O-N 2.76Å; L176-I428 HydrophobicContact CD1-CB 4.03Å; L176-I428 HydrophobicContact CD1-CD1 3.71Å; L176-I428 HydrophobicContact CD1-CG1 3.74Å; L176-I428 HydrophobicContact CD1-CG2 3.18Å; L176-I428 HydrophobicContact CG-CD1 4.26Å; L176-L431 HydrophobicContact CD1-CD1 4.03Å
177	W	87.1	Confident	87.5	Confident	133 Å²	133	43.3 Å²	43.3	50%	0.504	22%	0.221	S	C	.	.	H	α-helix	trans	-60.3	-33.9	175.9	66.4	-99	0	0	0	112.2	P175 L181 V424	P175-W177 VanDerWaalsContact C-N 3.35Å; P175-W177 HydrophobicContact CG-CD2 4.34Å; P175-W177 HydrophobicContact CG-CZ2 3.84Å; P175-W177 VanDerWaalsContact CG-NE1 3.32Å; P175-W177 PolarHBondContact O-N 3.12Å; W177-L181 HydrophobicContact CE3-CD1 3.88Å; W177-L181 HydrophobicContact CZ3-CD1 3.87Å; W177-L181 PolarHBondContact O-N 3.03Å; W177-L181 VanDerWaalsContact O-N 3.16Å; W177-V424 HydrophobicContact CB-CG2 4.4Å
178	A	89.9	Confident	86.9	Confident	17 Å²	17	47.3 Å²	47.3	14%	0.14	24%	0.238	C	C	.	.	H	α-helix	trans	-75.3	-37.1	174.8	0	0	0	0	0	110.8	I174 P175 L176 V180 L181 I182	I174-A178 HydrophobicContact CG2-CB 3.84Å; P175-A178 HydrophobicContact CG-CB 3.82Å; P175-A178 WeakPolarHBondContact O-CA 3.47Å; P175-A178 WeakPolarHBondContact O-CB 3.49Å; P175-A178 PolarHBondContact O-N 3.38Å; L176-A178 PolarHBondContact O-N 3.22Å; A178-V180 VanDerWaalsContact C-N 3.32Å; A178-V180 PolarHBondContact O-N 3.23Å; A178-L181 PolarHBondContact O-N 2.83Å; A178-I182 VanDerWaalsContact O-CG1 3.26Å; A178-I182 WeakPolarHBondContact O-CG1 3.3Å; A178-I182 PolarHBondContact O-N 3.14Å
179	G	90.2	Very high	86.3	Confident	0 Å²	0	50.2 Å²	50.2	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-55.3	-46	169.3	0	0	0	0	0	112	P175 L176 L181 I182 T183	P175-G179 PolarHBondContact O-N 2.83Å; L176-G179 CarbonylContact O-C 3.56Å; L176-G179 WeakPolarHBondContact O-CA 3.32Å; L176-G179 PolarHBondContact O-N 2.94Å; G179-L181 VanDerWaalsContact C-N 3.34Å; G179-L181 PolarHBondContact O-N 2.88Å; G179-I182 WeakPolarHBondContact O-CB 3.38Å; G179-I182 PolarHBondContact O-N 3.06Å; G179-I182 VanDerWaalsContact O-N 3.15Å; G179-T183 VanDerWaalsContact O-CG2 3.24Å; G179-T183 WeakPolarHBondContact O-CG2 3.38Å; G179-T183 PolarHBondContact O-N 2.79Å; G179-T183 VanDerWaalsContact O-N 3.16Å
180	V	89.7	Confident	85.3	Confident	0 Å²	0	47.3 Å²	47.3	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-60.2	-40.4	175.2	172.6	0	0	0	0	111.6	V159 A163 L176 A178 T183 I416 T419 I420	V159-V180 HydrophobicContact CG1-CB 4.31Å; V159-V180 HydrophobicContact CG1-CG1 3.72Å; V159-V180 HydrophobicContact CG1-CG2 4.16Å; A163-V180 HydrophobicContact CB-CB 4.44Å; A163-V180 HydrophobicContact CB-CG2 3.6Å; L176-V180 WeakPolarHBondContact O-CG2 3.32Å; L176-V180 PolarHBondContact O-N 2.76Å; A178-V180 VanDerWaalsContact C-N 3.32Å; A178-V180 PolarHBondContact O-N 3.23Å; V180-T183 PolarHBondContact O-N 3.04Å; V180-T183 PolarHBondContact O-OG1 3.26Å; V180-I416 HydrophobicContact CG1-CG2 4Å; V180-T419 HydrophobicContact CG1-CG2 4.1Å; V180-T419 HydrophobicContact CG2-CG2 3.77Å; V180-I420 HydrophobicContact CB-CG1 4.42Å; V180-I420 HydrophobicContact CG1-CD1 4.24Å; V180-I420 HydrophobicContact CG1-CG1 3.48Å; V180-I420 VanDerWaalsContact CG1-CG1 3.48Å
181	L	90.3	Very high	84.5	Confident	76 Å²	76	48.8 Å²	48.8	40%	0.398	25%	0.246	S	C	.	.	H	α-helix	trans	-68.3	-36.4	175.1	-73.7	172	0	0	0	112.6	W177 A178 G179 T183 I184 I420	W177-L181 HydrophobicContact CE3-CD1 3.88Å; W177-L181 HydrophobicContact CZ3-CD1 3.87Å; W177-L181 PolarHBondContact O-N 3.03Å; W177-L181 VanDerWaalsContact O-N 3.16Å; A178-L181 PolarHBondContact O-N 2.83Å; G179-L181 VanDerWaalsContact C-N 3.34Å; G179-L181 PolarHBondContact O-N 2.88Å; L181-T183 PolarHBondContact O-N 2.88Å; L181-I184 HydrophobicContact CD2-CD1 4.2Å; L181-I184 WeakPolarHBondContact O-CB 3.36Å; L181-I184 WeakPolarHBondContact O-CG1 3.35Å; L181-I184 PolarHBondContact O-N 2.95Å; L181-I184 VanDerWaalsContact O-N 3.13Å; L181-I420 HydrophobicContact CD2-CD1 3.5Å; L181-I420 HydrophobicContact CG-CD1 4.14Å
182	I	91.1	Very high	84.1	Confident	62 Å²	62	53.8 Å²	53.8	32%	0.318	27%	0.265	S	S	.	.	H	α-helix	trans	-64.2	-28.5	177.1	-68.5	162.6	0	0	0	110.9	I166 I174 A178 G179 I184 L185 D186	I166-I182 HydrophobicContact CD1-CB 4.15Å; I166-I182 HydrophobicContact CD1-CG2 3.76Å; I166-I182 HydrophobicContact CG2-CD1 4.26Å; I174-I182 HydrophobicContact CD1-CD1 4.15Å; I174-I182 HydrophobicContact CG2-CD1 3.82Å; A178-I182 VanDerWaalsContact O-CG1 3.26Å; A178-I182 WeakPolarHBondContact O-CG1 3.3Å; A178-I182 PolarHBondContact O-N 3.14Å; G179-I182 WeakPolarHBondContact O-CB 3.38Å; G179-I182 PolarHBondContact O-N 3.06Å; G179-I182 VanDerWaalsContact O-N 3.15Å; I182-I184 PolarHBondContact O-N 2.91Å; I182-I184 VanDerWaalsContact O-N 3.11Å; I182-L185 WeakPolarHBondContact O-CA 3.46Å; I182-L185 WeakPolarHBondContact O-CB 3.47Å; I182-L185 PolarHBondContact O-N 2.92Å; I182-D186 PolarHBondContact O-N 3.5Å
183	T	89.7	Confident	83.6	Confident	0 Å²	0	54.9 Å²	54.9	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-66.5	-11.1	175.8	78.3	0	0	0	0	113.9	V159 T162 G179 V180 L181 D186 R412	V159-T183 HydrophobicContact CG1-CG2 4.4Å; T162-T183 HydrophobicContact CG2-CG2 3.63Å; G179-T183 VanDerWaalsContact O-CG2 3.24Å; G179-T183 WeakPolarHBondContact O-CG2 3.38Å; G179-T183 PolarHBondContact O-N 2.79Å; G179-T183 VanDerWaalsContact O-N 3.16Å; V180-T183 PolarHBondContact O-N 3.04Å; V180-T183 PolarHBondContact O-OG1 3.26Å; L181-T183 PolarHBondContact O-N 2.88Å; T183-D186 WeakPolarHBondContact O-CB 3.5Å; T183-R412 PolarHBondContact O-NE 2.93Å
184	I	85.6	Confident	82.8	Confident	64 Å²	64	48.6 Å²	48.6	33%	0.328	24%	0.243	S	C	.	.	H	α-helix	trans	-67.9	-45.9	166.4	-59.6	173.7	0	0	0	109.4	L181 I182 D186 T187 I416	L181-I184 HydrophobicContact CD2-CD1 4.2Å; L181-I184 WeakPolarHBondContact O-CB 3.36Å; L181-I184 WeakPolarHBondContact O-CG1 3.35Å; L181-I184 PolarHBondContact O-N 2.95Å; L181-I184 VanDerWaalsContact O-N 3.13Å; I182-I184 PolarHBondContact O-N 2.91Å; I182-I184 VanDerWaalsContact O-N 3.11Å; I184-D186 PolarHBondContact O-N 3.47Å; I184-T187 WeakPolarHBondContact O-CB 3.4Å; I184-T187 PolarHBondContact O-N 2.89Å; I184-T187 PolarHBondContact O-OG1 2.94Å; I184-I416 HydrophobicContact CB-CD1 4.42Å; I184-I416 HydrophobicContact CD1-CD1 4.19Å; I184-I416 HydrophobicContact CG1-CD1 3.29Å
185	L	85	Confident	82.2	Confident	110 Å²	110	55 Å²	55	58%	0.576	27%	0.269	S	S	*	.	H	α-helix	trans	-64	-31.8	179.4	-62.3	178	0	0	0	111.3	I182 T187 F188	I182-L185 WeakPolarHBondContact O-CA 3.46Å; I182-L185 WeakPolarHBondContact O-CB 3.47Å; I182-L185 PolarHBondContact O-N 2.92Å; L185-T187 PolarHBondContact O-N 3.5Å; L185-F188 HydrophobicContact CD2-CD2 4.45Å; L185-F188 HydrophobicContact CD2-CE2 4.38Å; L185-F188 VanDerWaalsContact O-CB 3.3Å; L185-F188 WeakPolarHBondContact O-CB 3.48Å; L185-F188 WeakPolarHBondContact O-CD2 3.24Å; L185-F188 PolarHBondContact O-N 3.4Å
186	D	80.1	Confident	81.7	Confident	16 Å²	16	59.5 Å²	59.5	9%	0.086	28%	0.28	C	S	.	.	H	α-helix	trans	-61.1	-30.1	177.8	-175.6	36.6	0	0	0	114.4	I182 T183 I184 F188 T189 F190 Q380 R412	I182-D186 PolarHBondContact O-N 3.5Å; T183-D186 WeakPolarHBondContact O-CB 3.5Å; I184-D186 PolarHBondContact O-N 3.47Å; D186-F188 PolarHBondContact O-N 3.16Å; D186-F188 VanDerWaalsContact O-N 3.1Å; D186-T189 WeakPolarHBondContact O-CA 3.35Å; D186-T189 WeakPolarHBondContact O-CB 3.42Å; D186-T189 PolarHBondContact O-N 3.39Å; D186-T189 PolarHBondContact O-OG1 3.3Å; D186-T189 PolarHBondContact OD1-OG1 2.95Å; D186-F190 PolarHBondContact O-N 3.46Å; D186-Q380 PolarHBondContact OD1-NE2 3.21Å; D186-Q380 PolarHBondContact OD1-OE1 2.97Å; D186-Q380 PolarHBondContact OD2-NE2 3.21Å; D186-R412 IonicContact OD2-NH2 3.62Å
187	T	74.9	Confident	81.2	Confident	3 Å²	3	61 Å²	61	2%	0.018	30%	0.296	C	S	.	.	H	α-helix	trans	-59	-26.4	172.8	66.6	0	0	0	0	112.7	I184 L185 L191 V408 R412	I184-T187 WeakPolarHBondContact O-CB 3.4Å; I184-T187 PolarHBondContact O-N 2.89Å; I184-T187 PolarHBondContact O-OG1 2.94Å; L185-T187 PolarHBondContact O-N 3.5Å; T187-L191 WeakPolarHBondContact O-CG 3.33Å; T187-L191 PolarHBondContact O-N 2.91Å; T187-V408 HydrophobicContact CG2-CG1 3.67Å; T187-R412 HydrophobicContact CG2-CB 3.91Å; T187-R412 HydrophobicContact CG2-CG 3.56Å
188	F	79	Confident	80.5	Confident	97 Å²	97	55.6 Å²	55.6	43%	0.425	28%	0.277	S	S	.	.	H	α-helix	trans	-72.3	-33.7	172.6	-60.7	-70.4	0	0	0	111.7	L185 D186 F190 L191 F192	L185-F188 HydrophobicContact CD2-CD2 4.45Å; L185-F188 HydrophobicContact CD2-CE2 4.38Å; L185-F188 VanDerWaalsContact O-CB 3.3Å; L185-F188 WeakPolarHBondContact O-CB 3.48Å; L185-F188 WeakPolarHBondContact O-CD2 3.24Å; L185-F188 PolarHBondContact O-N 3.4Å; D186-F188 PolarHBondContact O-N 3.16Å; D186-F188 VanDerWaalsContact O-N 3.1Å; F188-F190 VanDerWaalsContact C-N 3.29Å; F188-F190 PolarHBondContact O-N 3.4Å; F188-L191 HydrophobicContact CD1-CD1 4.19Å; F188-L191 PolarHBondContact O-N 3.08Å; F188-L191 VanDerWaalsContact O-N 3.12Å; F188-F192 HydrophobicContact CB-CE2 4.33Å; F188-F192 WeakPolarHBondContact O-CD2 3.48Å; F188-F192 PolarHBondContact O-N 3.15Å
189	T	77.8	Confident	80	Confident	60 Å²	60	59 Å²	59	37%	0.368	29%	0.286	S	S	.	.	H	α-helix	trans	-55.7	-46.9	172.8	-44.8	0	0	0	0	110.5	D186 L191 F192 L193	D186-T189 WeakPolarHBondContact O-CA 3.35Å; D186-T189 WeakPolarHBondContact O-CB 3.42Å; D186-T189 PolarHBondContact O-N 3.39Å; D186-T189 PolarHBondContact O-OG1 3.3Å; D186-T189 PolarHBondContact OD1-OG1 2.95Å; T189-L191 PolarHBondContact O-N 3.26Å; T189-F192 PolarHBondContact O-N 3.21Å; T189-L193 HydrophobicContact CG2-CD1 4.09Å; T189-L193 WeakPolarHBondContact O-CG 3.33Å; T189-L193 PolarHBondContact O-N 3.17Å
190	F	72.6	Confident	79.6	Confident	1 Å²	1	65.4 Å²	65.4	0%	0.004	31%	0.314	C	S	.	.	H	α-helix	trans	-56.5	-48.5	173.8	163.9	-107.1	0	0	0	112.1	D186 F188 F192 L193 D194 T383 M384 T387 Y388 V408	D186-F190 PolarHBondContact O-N 3.46Å; F188-F190 VanDerWaalsContact C-N 3.29Å; F188-F190 PolarHBondContact O-N 3.4Å; F190-F192 VanDerWaalsContact C-N 3.26Å; F190-F192 PolarHBondContact O-N 2.97Å; F190-L193 PolarHBondContact O-N 3.47Å; F190-D194 HydrophobicContact CE2-CB 4.38Å; F190-D194 HydrophobicContact CZ-CB 4.35Å; F190-D194 PolarHBondContact O-N 3.1Å; F190-T383 HydrophobicContact CB-CG2 4.37Å; F190-M384 HydrophobicContact CD2-CB 3.91Å; F190-M384 HydrophobicContact CD2-CE 4.41Å; F190-M384 HydrophobicContact CD2-CG 3.46Å; F190-M384 VanDerWaalsContact CD2-CG 3.46Å; F190-M384 HydrophobicContact CD2-SD 3.68Å; F190-M384 HydrophobicContact CE2-CB 3.9Å; F190-M384 HydrophobicContact CE2-CG 3.97Å; F190-M384 HydrophobicContact CE2-SD 4.12Å; F190-M384 HydrophobicContact CG-CG 4.49Å; F190-T387 HydrophobicContact CE1-CG2 3.63Å; F190-T387 HydrophobicContact CZ-CG2 3.64Å; F190-Y388 HydrophobicContact CE2-CE2 4.38Å; F190-Y388 HydrophobicContact CZ-CE1 4.47Å; F190-V408 HydrophobicContact CD1-CG2 3.9Å; F190-V408 HydrophobicContact CE1-CG2 3.71Å
191	L	73.4	Confident	78.8	Confident	52 Å²	52	65.7 Å²	65.7	27%	0.272	32%	0.316	S	S	.	.	H	α-helix	trans	-63.4	-32.8	-179.4	-67.5	171.7	0	0	0	112.9	T187 F188 T189 W405	T187-L191 WeakPolarHBondContact O-CG 3.33Å; T187-L191 PolarHBondContact O-N 2.91Å; F188-L191 HydrophobicContact CD1-CD1 4.19Å; F188-L191 PolarHBondContact O-N 3.08Å; F188-L191 VanDerWaalsContact O-N 3.12Å; T189-L191 PolarHBondContact O-N 3.26Å; L191-W405 HydrophobicContact CD1-CB 3.47Å; L191-W405 VanDerWaalsContact CD1-CB 3.47Å; L191-W405 HydrophobicContact CD2-CB 3.57Å; L191-W405 HydrophobicContact CG-CB 4.17Å
192	F	78.2	Confident	78.2	Confident	147 Å²	147	62.6 Å²	62.6	65%	0.645	30%	0.3	S	S	*	.	H	α-helix	trans	-68.8	-41.1	171.4	-76.4	-65.9	0	0	0	111.6	F188 T189 F190 K195 Y196	F188-F192 HydrophobicContact CB-CE2 4.33Å; F188-F192 WeakPolarHBondContact O-CD2 3.48Å; F188-F192 PolarHBondContact O-N 3.15Å; T189-F192 PolarHBondContact O-N 3.21Å; F190-F192 VanDerWaalsContact C-N 3.26Å; F190-F192 PolarHBondContact O-N 2.97Å; F192-K195 PolarHBondContact O-N 3.14Å; F192-Y196 WeakPolarHBondContact O-CD2 3.39Å; F192-Y196 VanDerWaalsContact O-CE2 3.24Å; F192-Y196 WeakPolarHBondContact O-CE2 3.44Å
193	L	73.4	Confident	77.8	Confident	45 Å²	45	66.6 Å²	66.6	24%	0.236	32%	0.315	C	S	.	.	H	α-helix	trans	-70.1	-36.6	-179.2	-73.8	170.7	0	0	0	113.1	T189 F190 K195 Y196 F204 M384	T189-L193 HydrophobicContact CG2-CD1 4.09Å; T189-L193 WeakPolarHBondContact O-CG 3.33Å; T189-L193 PolarHBondContact O-N 3.17Å; F190-L193 PolarHBondContact O-N 3.47Å; L193-K195 PolarHBondContact O-N 3.21Å; L193-K195 VanDerWaalsContact O-N 3.15Å; L193-Y196 WeakPolarHBondContact O-CB 3.21Å; L193-Y196 PolarHBondContact O-N 2.87Å; L193-F204 HydrophobicContact CD1-CE1 4.35Å; L193-M384 HydrophobicContact CB-CE 3.91Å; L193-M384 HydrophobicContact CD1-CE 3.35Å; L193-M384 HydrophobicContact CG-CE 4.24Å
194	D	70.7	Confident	77.4	Confident	31 Å²	31	69.9 Å²	69.9	17%	0.166	33%	0.329	C	S	.	.	H	α-helix	trans	-58	-29.7	177.3	-168.7	37.8	0	0	0	112.2	F190 Y196 Y388 R404	F190-D194 HydrophobicContact CE2-CB 4.38Å; F190-D194 HydrophobicContact CZ-CB 4.35Å; F190-D194 PolarHBondContact O-N 3.1Å; D194-Y196 PolarHBondContact O-N 3.47Å; D194-Y388 PolarHBondContact OD1-OH 2.93Å; D194-R404 IonicContact OD1-CZ 3.75Å; D194-R404 IonicContact OD1-NH1 3.64Å; D194-R404 PolarHBondContact OD1-NH1 2.86Å; D194-R404 WeakPolarHBondContact OD2-CD 3.39Å; D194-R404 IonicContact OD2-CZ 2.7Å; D194-R404 IonicContact OD2-NE 3.57Å; D194-R404 IonicContact OD2-NH1 3.97Å; D194-R404 PolarHBondContact OD2-NH1 2.71Å
195	K	76.3	Confident	76.9	Confident	187 Å²	187	66.9 Å²	66.9	81%	0.813	31%	0.314	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.6	-19.6	177.6	-166.2	176	179	-177.7	0	113.8	F192 L193 G197	F192-K195 PolarHBondContact O-N 3.14Å; L193-K195 PolarHBondContact O-N 3.21Å; L193-K195 VanDerWaalsContact O-N 3.15Å; K195-G197 VanDerWaalsContact C-N 3.31Å; K195-G197 PolarHBondContact O-N 3.47Å
196	Y	75.2	Confident	76.7	Confident	144 Å²	144	62.6 Å²	62.6	57%	0.565	30%	0.297	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.6	-5.3	-175.5	-71.7	-85.1	0	0	0	114.1	F192 L193 D194 K200	F192-Y196 WeakPolarHBondContact O-CD2 3.39Å; F192-Y196 VanDerWaalsContact O-CE2 3.24Å; F192-Y196 WeakPolarHBondContact O-CE2 3.44Å; L193-Y196 WeakPolarHBondContact O-CB 3.21Å; L193-Y196 PolarHBondContact O-N 2.87Å; D194-Y196 PolarHBondContact O-N 3.47Å; Y196-K200 HydrophobicContact CD1-CD 4.49Å; Y196-K200 WeakPolarHBondContact O-CD 3.34Å
197	G	74.9	Confident	77	Confident	35 Å²	35	66 Å²	66	36%	0.361	31%	0.314	S	S	.	.			trans	83.8	156.1	177.5	0	0	0	0	0	113.8	K195 R199 K200 L201	K195-G197 VanDerWaalsContact C-N 3.31Å; K195-G197 PolarHBondContact O-N 3.47Å; G197-R199 PolarHBondContact O-N 3.42Å; G197-K200 PolarHBondContact O-N 3.17Å; G197-L201 PolarHBondContact O-N 2.96Å
198	L	73.2	Confident	77.2	Confident	20 Å²	20	66.9 Å²	66.9	11%	0.105	32%	0.319	C	S	.	.	H	α-helix	trans	-57.2	-43.2	-169.6	-173	64.1	0	0	0	113.5	F44 L73 K200 L201 E202	F44-L198 HydrophobicContact CD1-CB 4.04Å; F44-L198 HydrophobicContact CD1-CD1 3.91Å; F44-L198 HydrophobicContact CD1-CD2 3.83Å; F44-L198 HydrophobicContact CD1-CG 4.14Å; F44-L198 HydrophobicContact CE1-CD1 3.82Å; L73-L198 HydrophobicContact CD1-CD1 3.75Å; L198-K200 PolarHBondContact O-N 3.37Å; L198-L201 HydrophobicContact CD1-CD2 4.34Å; L198-L201 PolarHBondContact O-N 3.33Å; L198-E202 HydrophobicContact CD1-CG 4.47Å; L198-E202 HydrophobicContact CG-CG 4.26Å; L198-E202 VanDerWaalsContact O-CG 3.32Å; L198-E202 WeakPolarHBondContact O-CG 3.41Å; L198-E202 PolarHBondContact O-N 3.42Å
199	R	79.3	Confident	77.5	Confident	88 Å²	88	62.7 Å²	62.7	33%	0.332	30%	0.301	S	S	.	.	H	α-helix	trans	-65.3	-37.1	-175.1	-171	58.4	168.3	-165.5	-0.7	113.3	W65 T68 G197 L201 E202 F203	W65-R199 VanDerWaalsContact NE1-NH2 3.15Å; W65-R199 PolarHBondContact O-NH2 3.03Å; T68-R199 PolarHBondContact O-NH1 2.83Å; G197-R199 PolarHBondContact O-N 3.42Å; R199-L201 VanDerWaalsContact C-N 3.34Å; R199-E202 WeakPolarHBondContact CD-OE2 3.47Å; R199-E202 IonicContact NH1-OE2 2.8Å; R199-E202 PolarHBondContact NH1-OE2 3.15Å; R199-F203 PolarHBondContact O-N 3.14Å; R199-F203 VanDerWaalsContact O-N 3.13Å
200	K	80.6	Confident	78	Confident	135 Å²	135	63.8 Å²	63.8	59%	0.587	31%	0.307	S	S	*	.	H	α-helix	trans	-70.7	-36.7	177.3	-66.6	-171.2	-173.9	171.9	0	110.9	Y196 G197 L198 F203 F204	Y196-K200 HydrophobicContact CD1-CD 4.49Å; Y196-K200 WeakPolarHBondContact O-CD 3.34Å; G197-K200 PolarHBondContact O-N 3.17Å; L198-K200 PolarHBondContact O-N 3.37Å; K200-F203 PolarHBondContact O-N 3.21Å; K200-F204 WeakPolarHBondContact O-CB 3.36Å; K200-F204 PolarHBondContact O-N 2.89Å
201	L	73.2	Confident	78.5	Confident	6 Å²	6	67 Å²	67	3%	0.031	32%	0.324	C	S	.	.	H	α-helix	trans	-69.1	-42	176.9	177	153.9	0	0	0	111.3	L73 G197 L198 R199 F203 F204 F205 M384 Y388	L73-L201 HydrophobicContact CD1-CD2 4.48Å; L73-L201 HydrophobicContact CD2-CD2 3.68Å; G197-L201 PolarHBondContact O-N 2.96Å; L198-L201 HydrophobicContact CD1-CD2 4.34Å; L198-L201 PolarHBondContact O-N 3.33Å; R199-L201 VanDerWaalsContact C-N 3.34Å; L201-F203 VanDerWaalsContact C-N 3.34Å; L201-F203 PolarHBondContact O-N 3.49Å; L201-F204 PolarHBondContact O-N 3.04Å; L201-F205 HydrophobicContact CD1-CE2 4.5Å; L201-F205 HydrophobicContact CD2-CD2 3.71Å; L201-F205 HydrophobicContact CD2-CE2 3.25Å; L201-F205 HydrophobicContact CD2-CZ 4.23Å; L201-F205 HydrophobicContact CG-CD2 4.18Å; L201-F205 HydrophobicContact CG-CE2 3.63Å; L201-F205 HydrophobicContact CG-CZ 4.23Å; L201-F205 WeakPolarHBondContact O-CD2 3.5Å; L201-F205 WeakPolarHBondContact O-CG 3.39Å; L201-F205 PolarHBondContact O-N 3.27Å; L201-M384 HydrophobicContact CD1-SD 3.57Å; L201-M384 VanDerWaalsContact CD1-SD 3.57Å; L201-M384 HydrophobicContact CG-SD 4.13Å; L201-Y388 HydrophobicContact CD1-CE2 4.48Å
202	E	79.1	Confident	78.9	Confident	12 Å²	12	64.7 Å²	64.7	6%	0.056	31%	0.312	C	S	.	.	H	α-helix	trans	-55.7	-45.8	169.6	-72.4	171	173.7	0	0	111.7	G69 L73 L198 R199 F205 G206 R273	G69-E202 VanDerWaalsContact CA-OE1 3.31Å; G69-E202 WeakPolarHBondContact CA-OE1 3.49Å; L73-E202 HydrophobicContact CD1-CG 3.75Å; L73-E202 HydrophobicContact CG-CG 4.26Å; L198-E202 HydrophobicContact CD1-CG 4.47Å; L198-E202 HydrophobicContact CG-CG 4.26Å; L198-E202 VanDerWaalsContact O-CG 3.32Å; L198-E202 WeakPolarHBondContact O-CG 3.41Å; L198-E202 PolarHBondContact O-N 3.42Å; R199-E202 WeakPolarHBondContact CD-OE2 3.47Å; R199-E202 IonicContact NH1-OE2 2.8Å; R199-E202 PolarHBondContact NH1-OE2 3.15Å; E202-F205 PolarHBondContact O-N 2.93Å; E202-G206 PolarHBondContact O-N 2.96Å; E202-R273 IonicContact OE1-CZ 2.88Å; E202-R273 IonicContact OE1-NH1 2.91Å; E202-R273 PolarHBondContact OE1-NH1 3.06Å; E202-R273 IonicContact OE1-NH2 3.95Å; E202-R273 PolarHBondContact OE1-NH2 3.42Å; E202-R273 IonicContact OE2-NH2 3.18Å; E202-R273 PolarHBondContact OE2-NH2 3.16Å
203	F	82.7	Confident	79.4	Confident	145 Å²	145	59 Å²	59	64%	0.636	29%	0.292	S	S	*	.	H	α-helix	trans	-66	-43.3	177.6	177.8	-97.1	0	0	0	112.6	R199 K200 L201 F205 G206 L207	R199-F203 PolarHBondContact O-N 3.14Å; R199-F203 VanDerWaalsContact O-N 3.13Å; K200-F203 PolarHBondContact O-N 3.21Å; L201-F203 VanDerWaalsContact C-N 3.34Å; L201-F203 PolarHBondContact O-N 3.49Å; F203-F205 VanDerWaalsContact C-N 3.27Å; F203-F205 PolarHBondContact O-N 3.34Å; F203-G206 PolarHBondContact O-N 2.95Å; F203-L207 PolarHBondContact O-N 3.28Å
204	F	79.5	Confident	80.1	Confident	69 Å²	69	61.6 Å²	61.6	30%	0.303	31%	0.309	S	S	.	.	H	α-helix	trans	-56.5	-43.7	176.1	175.2	-106.6	0	0	0	111.1	L193 K200 L201 L207 L208	L193-F204 HydrophobicContact CD1-CE1 4.35Å; K200-F204 WeakPolarHBondContact O-CB 3.36Å; K200-F204 PolarHBondContact O-N 2.89Å; L201-F204 PolarHBondContact O-N 3.04Å; F204-L207 WeakPolarHBondContact O-CB 3.32Å; F204-L207 PolarHBondContact O-N 3.3Å; F204-L208 HydrophobicContact CD1-CD1 4.12Å; F204-L208 HydrophobicContact CE1-CD1 3.53Å; F204-L208 HydrophobicContact CE1-CG 4.34Å; F204-L208 HydrophobicContact CZ-CD1 3.76Å; F204-L208 HydrophobicContact CZ-CD2 4.43Å; F204-L208 HydrophobicContact CZ-CG 4.29Å; F204-L208 WeakPolarHBondContact O-CG 3.49Å; F204-L208 PolarHBondContact O-N 3.22Å; F204-L208 VanDerWaalsContact O-N 3.12Å
205	F	75.6	Confident	80.6	Confident	1 Å²	1	61.1 Å²	61.1	0%	0.004	31%	0.307	C	S	.	.	H	α-helix	trans	-69.6	-38.8	175.6	-65.2	-45.2	0	0	0	113.9	L73 I76 L201 E202 F203 L207 L208 I209 S381 M384	L73-F205 HydrophobicContact CD2-CD2 3.34Å; L73-F205 HydrophobicContact CD2-CE2 3.35Å; L73-F205 HydrophobicContact CG-CD2 4.4Å; I76-F205 HydrophobicContact CD1-CB 3.74Å; I76-F205 HydrophobicContact CD1-CD1 3.8Å; I76-F205 HydrophobicContact CD1-CD2 3.53Å; I76-F205 HydrophobicContact CD1-CE1 4.25Å; I76-F205 HydrophobicContact CD1-CE2 3.89Å; I76-F205 HydrophobicContact CD1-CG 3.43Å; I76-F205 VanDerWaalsContact CD1-CG 3.43Å; I76-F205 HydrophobicContact CD1-CZ 4.23Å; L201-F205 HydrophobicContact CD1-CE2 4.5Å; L201-F205 HydrophobicContact CD2-CD2 3.71Å; L201-F205 HydrophobicContact CD2-CE2 3.25Å; L201-F205 HydrophobicContact CD2-CZ 4.23Å; L201-F205 HydrophobicContact CG-CD2 4.18Å; L201-F205 HydrophobicContact CG-CE2 3.63Å; L201-F205 HydrophobicContact CG-CZ 4.23Å; L201-F205 WeakPolarHBondContact O-CD2 3.5Å; L201-F205 WeakPolarHBondContact O-CG 3.39Å; L201-F205 PolarHBondContact O-N 3.27Å; E202-F205 PolarHBondContact O-N 2.93Å; F203-F205 VanDerWaalsContact C-N 3.27Å; F203-F205 PolarHBondContact O-N 3.34Å; F205-L207 PolarHBondContact O-N 3.35Å; F205-L208 HydrophobicContact CD1-CD1 4.16Å; F205-L208 PolarHBondContact O-N 2.95Å; F205-L208 VanDerWaalsContact O-N 3.11Å; F205-I209 WeakPolarHBondContact O-CG1 3.44Å; F205-I209 PolarHBondContact O-N 3.39Å; F205-S381 VanDerWaalsContact CD1-OG 3.23Å; F205-S381 WeakPolarHBondContact CD1-OG 3.38Å; F205-S381 VanDerWaalsContact CE1-CB 3.43Å; F205-S381 WeakPolarHBondContact CE1-OG 2.93Å; F205-M384 HydrophobicContact CE1-CE 4.21Å; F205-M384 HydrophobicContact CE1-SD 4.24Å; F205-M384 HydrophobicContact CE2-SD 4.17Å; F205-M384 HydrophobicContact CZ-CB 3.96Å; F205-M384 HydrophobicContact CZ-CE 3.96Å; F205-M384 HydrophobicContact CZ-CG 3.74Å; F205-M384 HydrophobicContact CZ-SD 3.41Å; F205-M384 WeakPolarHBondContact CZ-SD 3.31Å
206	G	81.7	Confident	80.9	Confident	21 Å²	21	52.5 Å²	52.5	22%	0.216	27%	0.27	C	S	.	.	H	α-helix	trans	-55.6	-38.8	171.7	0	0	0	0	0	112.1	E202 F203 T210	E202-G206 PolarHBondContact O-N 2.96Å; F203-G206 PolarHBondContact O-N 2.95Å; G206-T210 WeakPolarHBondContact O-CB 3.45Å; G206-T210 PolarHBondContact O-N 3.16Å; G206-T210 PolarHBondContact O-OG1 2.81Å
207	L	85.9	Confident	81.6	Confident	86 Å²	86	46.1 Å²	46.1	45%	0.45	25%	0.248	S	C	.	.	H	α-helix	trans	-64.4	-47.1	173.9	179.1	68.3	0	0	0	111.9	F203 F204 F205 T210 I211	F203-L207 PolarHBondContact O-N 3.28Å; F204-L207 WeakPolarHBondContact O-CB 3.32Å; F204-L207 PolarHBondContact O-N 3.3Å; F205-L207 PolarHBondContact O-N 3.35Å; L207-T210 WeakPolarHBondContact O-CB 3.2Å; L207-T210 PolarHBondContact O-N 2.95Å; L207-I211 HydrophobicContact CD1-CD1 4.44Å; L207-I211 HydrophobicContact CG-CD1 4.15Å; L207-I211 WeakPolarHBondContact O-CG1 3.48Å; L207-I211 PolarHBondContact O-N 3.16Å
208	L	79.4	Confident	82.3	Confident	22 Å²	22	51.2 Å²	51.2	12%	0.115	26%	0.257	C	S	.	.	H	α-helix	trans	-62.1	-46.8	179.7	-66.5	-179.1	0	0	0	112.4	F204 F205 T210 I211 M212 A377	F204-L208 HydrophobicContact CD1-CD1 4.12Å; F204-L208 HydrophobicContact CE1-CD1 3.53Å; F204-L208 HydrophobicContact CE1-CG 4.34Å; F204-L208 HydrophobicContact CZ-CD1 3.76Å; F204-L208 HydrophobicContact CZ-CD2 4.43Å; F204-L208 HydrophobicContact CZ-CG 4.29Å; F204-L208 WeakPolarHBondContact O-CG 3.49Å; F204-L208 PolarHBondContact O-N 3.22Å; F204-L208 VanDerWaalsContact O-N 3.12Å; F205-L208 HydrophobicContact CD1-CD1 4.16Å; F205-L208 PolarHBondContact O-N 2.95Å; F205-L208 VanDerWaalsContact O-N 3.11Å; L208-T210 VanDerWaalsContact C-N 3.26Å; L208-T210 PolarHBondContact O-N 3.34Å; L208-I211 WeakPolarHBondContact O-CB 3.31Å; L208-I211 PolarHBondContact O-N 3Å; L208-I211 VanDerWaalsContact O-N 3.16Å; L208-M212 WeakPolarHBondContact O-CG 3.28Å; L208-M212 PolarHBondContact O-N 3.35Å; L208-A377 HydrophobicContact CB-CB 4.27Å; L208-A377 HydrophobicContact CD1-CB 3.82Å; L208-A377 HydrophobicContact CD2-CB 3.65Å; L208-A377 HydrophobicContact CG-CB 4.09Å
209	I	85.2	Confident	82.9	Confident	9 Å²	9	50.3 Å²	50.3	5%	0.046	25%	0.253	C	S	.	.	H	α-helix	trans	-60.4	-39.6	176	-65.3	171	0	0	0	110.5	F72 I76 L79 F205 I211 M212 A213 V300 I304	F72-I209 HydrophobicContact CD1-CD1 4.26Å; I76-I209 HydrophobicContact CG1-CD1 4.2Å; L79-I209 HydrophobicContact CD1-CD1 4.38Å; L79-I209 HydrophobicContact CD1-CG1 3.99Å; L79-I209 HydrophobicContact CD1-CG2 4.04Å; F205-I209 WeakPolarHBondContact O-CG1 3.44Å; F205-I209 PolarHBondContact O-N 3.39Å; I209-I211 PolarHBondContact O-N 3.09Å; I209-M212 PolarHBondContact O-N 2.99Å; I209-A213 WeakPolarHBondContact O-CB 3.29Å; I209-A213 PolarHBondContact O-N 3.12Å; I209-V300 HydrophobicContact CG2-CG1 3.79Å; I209-I304 HydrophobicContact CG2-CD1 4.06Å
210	T	87.5	Confident	83.4	Confident	83 Å²	83	47.6 Å²	47.6	51%	0.509	24%	0.243	S	C	.	.	H	α-helix	trans	-63	-42.4	176.8	-59.1	0	0	0	0	111.4	G206 L207 L208 A213 V214	G206-T210 WeakPolarHBondContact O-CB 3.45Å; G206-T210 PolarHBondContact O-N 3.16Å; G206-T210 PolarHBondContact O-OG1 2.81Å; L207-T210 WeakPolarHBondContact O-CB 3.2Å; L207-T210 PolarHBondContact O-N 2.95Å; L208-T210 VanDerWaalsContact C-N 3.26Å; L208-T210 PolarHBondContact O-N 3.34Å; T210-A213 PolarHBondContact O-N 2.8Å; T210-V214 HydrophobicContact CG2-CG2 4.41Å; T210-V214 VanDerWaalsContact O-CG2 3.3Å; T210-V214 WeakPolarHBondContact O-CG2 3.22Å; T210-V214 PolarHBondContact O-N 3.36Å
211	I	83.7	Confident	83.9	Confident	68 Å²	68	46.6 Å²	46.6	35%	0.349	24%	0.243	S	C	.	.	H	α-helix	trans	-60.9	-46.9	175.9	-67.7	165.1	0	0	0	110.2	L207 L208 I209 A213 V214 T215	L207-I211 HydrophobicContact CD1-CD1 4.44Å; L207-I211 HydrophobicContact CG-CD1 4.15Å; L207-I211 WeakPolarHBondContact O-CG1 3.48Å; L207-I211 PolarHBondContact O-N 3.16Å; L208-I211 WeakPolarHBondContact O-CB 3.31Å; L208-I211 PolarHBondContact O-N 3Å; L208-I211 VanDerWaalsContact O-N 3.16Å; I209-I211 PolarHBondContact O-N 3.09Å; I211-A213 PolarHBondContact O-N 3.41Å; I211-V214 PolarHBondContact O-N 3.12Å; I211-T215 HydrophobicContact CG2-CG2 4.26Å; I211-T215 WeakPolarHBondContact O-CB 3.2Å; I211-T215 WeakPolarHBondContact O-CG2 2.97Å; I211-T215 PolarHBondContact O-N 3.45Å; I211-T215 PolarHBondContact O-OG1 3.44Å
212	M	82.4	Confident	84.6	Confident	5 Å²	5	49.3 Å²	49.3	3%	0.025	26%	0.259	C	S	.	.	H	α-helix	trans	-60.2	-46	176.7	-66.4	172	70.4	0	0	111.9	L79 I84 L208 I209 V214 T215 F216 I304 A378	L79-M212 HydrophobicContact CB-CE 4.14Å; I84-M212 HydrophobicContact CD1-CE 3.7Å; L208-M212 WeakPolarHBondContact O-CG 3.28Å; L208-M212 PolarHBondContact O-N 3.35Å; I209-M212 PolarHBondContact O-N 2.99Å; M212-V214 PolarHBondContact O-N 2.82Å; M212-T215 WeakPolarHBondContact CA-OG1 3.32Å; M212-T215 PolarHBondContact O-N 2.76Å; M212-T215 PolarHBondContact O-OG1 2.8Å; M212-F216 HydrophobicContact CB-CD2 4.2Å; M212-F216 HydrophobicContact CB-CE2 4.23Å; M212-F216 HydrophobicContact CE-CE2 4.22Å; M212-F216 WeakPolarHBondContact O-CB 3.15Å; M212-F216 WeakPolarHBondContact O-CD2 3.37Å; M212-F216 PolarHBondContact O-N 2.78Å; M212-I304 HydrophobicContact CB-CD1 4.29Å; M212-A378 HydrophobicContact CE-CB 4.48Å
213	A	88.1	Confident	85	Confident	27 Å²	27	50.6 Å²	50.6	22%	0.223	27%	0.268	C	S	.	.	H	α-helix	trans	-61.1	-43.6	179	0	0	0	0	0	112.8	I209 T210 I211 G217 I304	I209-A213 WeakPolarHBondContact O-CB 3.29Å; I209-A213 PolarHBondContact O-N 3.12Å; T210-A213 PolarHBondContact O-N 2.8Å; I211-A213 PolarHBondContact O-N 3.41Å; A213-G217 WeakPolarHBondContact O-CA 3.35Å; A213-G217 PolarHBondContact O-N 2.75Å; A213-I304 HydrophobicContact CB-CD1 4.09Å; A213-I304 HydrophobicContact CB-CG1 4.07Å
214	V	87.8	Confident	85.3	Confident	99 Å²	99	51.8 Å²	51.8	60%	0.6	27%	0.273	S	S	*	.	H	α-helix	trans	-66.8	-41.7	179.1	169.7	0	0	0	0	111.1	T210 I211 M212 Y218	T210-V214 HydrophobicContact CG2-CG2 4.41Å; T210-V214 VanDerWaalsContact O-CG2 3.3Å; T210-V214 WeakPolarHBondContact O-CG2 3.22Å; T210-V214 PolarHBondContact O-N 3.36Å; I211-V214 PolarHBondContact O-N 3.12Å; M212-V214 PolarHBondContact O-N 2.82Å; V214-Y218 WeakPolarHBondContact O-CB 3.45Å; V214-Y218 PolarHBondContact O-N 3.17Å
215	T	81.5	Confident	85.7	Confident	21 Å²	21	48.9 Å²	48.9	13%	0.129	26%	0.261	C	S	.	.	H	α-helix	trans	-74.9	-49.4	-173.2	51.8	0	0	0	0	112	I211 M212 G217 Y218 E219 I370	I211-T215 HydrophobicContact CG2-CG2 4.26Å; I211-T215 WeakPolarHBondContact O-CB 3.2Å; I211-T215 WeakPolarHBondContact O-CG2 2.97Å; I211-T215 PolarHBondContact O-N 3.45Å; I211-T215 PolarHBondContact O-OG1 3.44Å; M212-T215 WeakPolarHBondContact CA-OG1 3.32Å; M212-T215 PolarHBondContact O-N 2.76Å; M212-T215 PolarHBondContact O-OG1 2.8Å; T215-G217 VanDerWaalsContact C-N 3.33Å; T215-G217 PolarHBondContact O-N 2.79Å; T215-Y218 WeakPolarHBondContact O-CB 3.15Å; T215-Y218 PolarHBondContact O-N 2.84Å; T215-E219 PolarHBondContact O-N 3.45Å; T215-E219 VanDerWaalsContact O-N 3.07Å; T215-I370 HydrophobicContact CG2-CB 4.44Å; T215-I370 HydrophobicContact CG2-CD1 4.38Å; T215-I370 HydrophobicContact CG2-CG1 4.49Å; T215-I370 HydrophobicContact CG2-CG2 3.19Å
216	F	83.8	Confident	86.5	Confident	6 Å²	6	52.8 Å²	52.8	3%	0.026	28%	0.282	C	S	.	.	H	α-helix	trans	-67.1	-34.7	172.8	-66.7	-49.2	0	0	0	112.9	M212 Y218 E219 Y220 I304 F307 V308 W371	M212-F216 HydrophobicContact CB-CD2 4.2Å; M212-F216 HydrophobicContact CB-CE2 4.23Å; M212-F216 HydrophobicContact CE-CE2 4.22Å; M212-F216 WeakPolarHBondContact O-CB 3.15Å; M212-F216 WeakPolarHBondContact O-CD2 3.37Å; M212-F216 PolarHBondContact O-N 2.78Å; F216-Y218 VanDerWaalsContact C-N 3.31Å; F216-Y218 PolarHBondContact O-N 3.35Å; F216-E219 PolarHBondContact O-N 3.09Å; F216-Y220 VanDerWaalsContact O-CB 3.32Å; F216-Y220 WeakPolarHBondContact O-CB 3.32Å; F216-Y220 PolarHBondContact O-N 3.01Å; F216-I304 HydrophobicContact CD2-CG2 3.74Å; F216-I304 HydrophobicContact CE2-CG2 4.3Å; F216-F307 HydrophobicContact CB-CB 3.93Å; F216-F307 HydrophobicContact CB-CD2 4.18Å; F216-V308 HydrophobicContact CD1-CG2 4.22Å; F216-V308 HydrophobicContact CD2-CG2 4.13Å; F216-V308 HydrophobicContact CE1-CG2 4.3Å; F216-V308 HydrophobicContact CE2-CG2 4.19Å; F216-V308 HydrophobicContact CG-CG2 4.15Å; F216-V308 HydrophobicContact CZ-CG2 4.29Å; F216-W371 AromaticContact CE1-CE3 3.32Å; F216-W371 HydrophobicContact CE1-CE3 3.32Å; F216-W371 AromaticContact CE1-CZ3 3.35Å; F216-W371 HydrophobicContact CE1-CZ3 3.35Å; F216-W371 AromaticContact CZ-CE3 3.39Å; F216-W371 HydrophobicContact CZ-CE3 3.39Å; F216-W371 AromaticContact CZ-CZ3 3.34Å; F216-W371 HydrophobicContact CZ-CZ3 3.34Å
217	G	89.4	Confident	87	Confident	10 Å²	10	56.1 Å²	56.1	10%	0.103	29%	0.291	C	S	.	.	H	α-helix	trans	-61.6	-40	172.5	0	0	0	0	0	112.1	A213 T215 I221	A213-G217 WeakPolarHBondContact O-CA 3.35Å; A213-G217 PolarHBondContact O-N 2.75Å; T215-G217 VanDerWaalsContact C-N 3.33Å; T215-G217 PolarHBondContact O-N 2.79Å; G217-I221 WeakPolarHBondContact O-CD1 3.33Å; G217-I221 VanDerWaalsContact O-CG1 3.25Å; G217-I221 WeakPolarHBondContact O-CG1 3.35Å; G217-I221 PolarHBondContact O-N 2.83Å; G217-I221 VanDerWaalsContact O-N 3.15Å
218	Y	88.2	Confident	87.3	Confident	142 Å²	142	58.2 Å²	58.2	56%	0.557	30%	0.302	S	S	*	.	H	α-helix	trans	-63.2	-50	174.2	177.7	-97.8	0	0	0	111.5	V214 T215 F216 Y220 I221 V222	V214-Y218 WeakPolarHBondContact O-CB 3.45Å; V214-Y218 PolarHBondContact O-N 3.17Å; T215-Y218 WeakPolarHBondContact O-CB 3.15Å; T215-Y218 PolarHBondContact O-N 2.84Å; F216-Y218 VanDerWaalsContact C-N 3.31Å; F216-Y218 PolarHBondContact O-N 3.35Å; Y218-Y220 VanDerWaalsContact C-N 3.32Å; Y218-Y220 PolarHBondContact O-N 3.43Å; Y218-I221 PolarHBondContact O-N 3.29Å; Y218-I221 VanDerWaalsContact O-N 3.13Å; Y218-V222 HydrophobicContact CD1-CG2 4.17Å; Y218-V222 HydrophobicContact CD2-CG2 4.43Å; Y218-V222 HydrophobicContact CE1-CG2 3.75Å; Y218-V222 HydrophobicContact CE2-CG2 4.04Å; Y218-V222 HydrophobicContact CG-CG2 4.49Å; Y218-V222 WeakPolarHBondContact O-CG2 3.34Å; Y218-V222 PolarHBondContact O-N 2.94Å
219	E	85.9	Confident	88	Confident	2 Å²	2	59.7 Å²	59.7	1%	0.009	32%	0.315	C	S	.	.	H	α-helix	trans	-58.5	-43.4	178.5	-69.8	176.4	173.5	0	0	112	T215 F216 I221 V222 V223 V311 L359 F363	T215-E219 PolarHBondContact O-N 3.45Å; T215-E219 VanDerWaalsContact O-N 3.07Å; F216-E219 PolarHBondContact O-N 3.09Å; E219-I221 VanDerWaalsContact C-N 3.33Å; E219-I221 PolarHBondContact O-N 3.27Å; E219-V222 PolarHBondContact O-N 2.99Å; E219-V223 WeakPolarHBondContact O-CB 3.45Å; E219-V223 VanDerWaalsContact O-CG2 3.25Å; E219-V223 WeakPolarHBondContact O-CG2 3.15Å; E219-V223 PolarHBondContact O-N 3.31Å; E219-V311 HydrophobicContact CB-CG2 4.04Å; E219-L359 HydrophobicContact CG-CD2 4.45Å; E219-L359 VanDerWaalsContact OE2-CD2 3.29Å; E219-L359 WeakPolarHBondContact OE2-CD2 3.3Å; E219-F363 HydrophobicContact CG-CD2 4.47Å
220	Y	91	Very high	88.3	Confident	30 Å²	30	59.5 Å²	59.5	12%	0.118	31%	0.314	C	S	.	.	H	α-helix	trans	-56.7	-44.8	174.9	178.6	-93.3	0	0	0	112.6	F216 Y218 V222 K224 P225 Q227 L230 F307	F216-Y220 VanDerWaalsContact O-CB 3.32Å; F216-Y220 WeakPolarHBondContact O-CB 3.32Å; F216-Y220 PolarHBondContact O-N 3.01Å; Y218-Y220 VanDerWaalsContact C-N 3.32Å; Y218-Y220 PolarHBondContact O-N 3.43Å; Y220-V222 VanDerWaalsContact C-N 3.34Å; Y220-V222 PolarHBondContact O-N 3.44Å; Y220-K224 PolarHBondContact O-N 3.16Å; Y220-P225 HydrophobicContact CD2-CG 3.75Å; Y220-P225 HydrophobicContact CE2-CG 3.36Å; Y220-P225 VanDerWaalsContact O-CD 3.23Å; Y220-P225 WeakPolarHBondContact O-CD 3.41Å; Y220-Q227 VanDerWaalsContact OH-CD 3.25Å; Y220-Q227 PolarHBondContact OH-NE2 2.63Å; Y220-Q227 PolarHBondContact OH-OE1 3.33Å; Y220-L230 HydrophobicContact CE2-CD1 3.68Å; Y220-L230 VanDerWaalsContact OH-CD1 3.25Å; Y220-L230 WeakPolarHBondContact OH-CD1 3.45Å; Y220-F307 AromaticContact CD1-CD1 3.93Å; Y220-F307 HydrophobicContact CD1-CD1 3.93Å; Y220-F307 AromaticContact CD1-CE1 3.89Å; Y220-F307 HydrophobicContact CD1-CE1 3.89Å; Y220-F307 HydrophobicContact CD2-CB 4.49Å; Y220-F307 AromaticContact CD2-CD1 3.63Å; Y220-F307 HydrophobicContact CD2-CD1 3.63Å; Y220-F307 HydrophobicContact CD2-CE1 4.36Å; Y220-F307 HydrophobicContact CD2-CG 4.45Å; Y220-F307 HydrophobicContact CE1-CD1 4.46Å; Y220-F307 HydrophobicContact CE1-CE1 4.26Å; Y220-F307 HydrophobicContact CE2-CD1 4.16Å; Y220-F307 AromaticContact CG-CD1 3.48Å; Y220-F307 HydrophobicContact CG-CD1 3.48Å; Y220-F307 VanDerWaalsContact CG-CD1 3.48Å; Y220-F307 AromaticContact CG-CE1 3.94Å; Y220-F307 HydrophobicContact CG-CE1 3.94Å; Y220-F307 HydrophobicContact CG-CG 4.27Å
221	I	91.4	Very high	88.6	Confident	115 Å²	115	59.9 Å²	59.9	59%	0.59	31%	0.312	S	S	*	.	H	α-helix	trans	-66.8	-36.2	178.8	-67.9	165	0	0	0	111.3	G217 Y218 E219 K224	G217-I221 WeakPolarHBondContact O-CD1 3.33Å; G217-I221 VanDerWaalsContact O-CG1 3.25Å; G217-I221 WeakPolarHBondContact O-CG1 3.35Å; G217-I221 PolarHBondContact O-N 2.83Å; G217-I221 VanDerWaalsContact O-N 3.15Å; Y218-I221 PolarHBondContact O-N 3.29Å; Y218-I221 VanDerWaalsContact O-N 3.13Å; E219-I221 VanDerWaalsContact C-N 3.33Å; E219-I221 PolarHBondContact O-N 3.27Å; I221-K224 WeakPolarHBondContact O-CG 3.49Å
222	V	88	Confident	89	Confident	62 Å²	62	65.3 Å²	65.3	38%	0.376	33%	0.328	S	S	.	.	H	α-helix	trans	-75.2	-43.1	-179.6	-178.9	0	0	0	0	111.5	Y218 E219 Y220 K224 F363	Y218-V222 HydrophobicContact CD1-CG2 4.17Å; Y218-V222 HydrophobicContact CD2-CG2 4.43Å; Y218-V222 HydrophobicContact CE1-CG2 3.75Å; Y218-V222 HydrophobicContact CE2-CG2 4.04Å; Y218-V222 HydrophobicContact CG-CG2 4.49Å; Y218-V222 WeakPolarHBondContact O-CG2 3.34Å; Y218-V222 PolarHBondContact O-N 2.94Å; E219-V222 PolarHBondContact O-N 2.99Å; Y220-V222 VanDerWaalsContact C-N 3.34Å; Y220-V222 PolarHBondContact O-N 3.44Å; V222-K224 PolarHBondContact O-N 2.86Å; V222-F363 HydrophobicContact CB-CD1 4.26Å; V222-F363 HydrophobicContact CB-CE1 4.05Å; V222-F363 HydrophobicContact CG1-CD1 3.68Å; V222-F363 HydrophobicContact CG1-CE1 3.54Å
223	V	87	Confident	89.5	Confident	39 Å²	39	65.5 Å²	65.5	24%	0.236	33%	0.332	C	S	.	.	H	α-helix	trans	-60.2	-34.3	176.1	171.4	0	0	0	0	111.7	E219 V311 A314 F363	E219-V223 WeakPolarHBondContact O-CB 3.45Å; E219-V223 VanDerWaalsContact O-CG2 3.25Å; E219-V223 WeakPolarHBondContact O-CG2 3.15Å; E219-V223 PolarHBondContact O-N 3.31Å; V223-V311 HydrophobicContact CG2-CB 4.46Å; V223-V311 HydrophobicContact CG2-CG1 4.11Å; V223-V311 HydrophobicContact CG2-CG2 4.14Å; V223-A314 HydrophobicContact CG1-CB 3.5Å; V223-F363 HydrophobicContact CG2-CE1 4.1Å; V223-F363 HydrophobicContact CG2-CE2 3.93Å; V223-F363 HydrophobicContact CG2-CZ 3.27Å
224	K	89	Confident	89.7	Confident	171 Å²	171	65.1 Å²	65.1	74%	0.743	33%	0.326	S	S	*	.			trans	49.2	59.5	-174.6	-60.9	-179.1	-179.1	174.8	0	112.1	Y220 I221 V222	Y220-K224 PolarHBondContact O-N 3.16Å; I221-K224 WeakPolarHBondContact O-CG 3.49Å; V222-K224 PolarHBondContact O-N 2.86Å
225	P	88.5	Confident	89.9	Confident	7 Å²	7	67.2 Å²	67.2	5%	0.045	33%	0.327	C	S	.	.			trans	-59.7	151.8	176.5	26.6	-32.3	0	0	0	110.4	Y96 Y220 Q227	Y96-P225 VanDerWaalsContact OH-CB 3.27Å; Y96-P225 WeakPolarHBondContact OH-CB 3.47Å; Y220-P225 HydrophobicContact CD2-CG 3.75Å; Y220-P225 HydrophobicContact CE2-CG 3.36Å; Y220-P225 VanDerWaalsContact O-CD 3.23Å; Y220-P225 WeakPolarHBondContact O-CD 3.41Å; P225-Q227 PolarHBondContact O-N 2.76Å; P225-Q227 PolarHBondContact O-NE2 3.42Å
226	D	91.8	Very high	90.3	Very high	84 Å²	84	69.3 Å²	69.3	45%	0.449	34%	0.34	S	S	.	.			trans	-62.3	105.4	178.5	175.5	35.3	0	0	0	110.7	L228 S229 L230	D226-L228 PolarHBondContact O-N 3.25Å; D226-L228 PolarHBondContact OD1-N 2.9Å; D226-S229 PolarHBondContact O-N 2.99Å; D226-S229 WeakPolarHBondContact OD2-CB 3.35Å; D226-S229 PolarHBondContact OD2-N 3.1Å; D226-S229 VanDerWaalsContact OD2-N 3.09Å; D226-S229 PolarHBondContact OD2-OG 3.35Å; D226-L230 PolarHBondContact O-N 3.41Å
227	Q	91.9	Very high	90.5	Very high	90 Å²	90	73.6 Å²	73.6	42%	0.421	37%	0.368	S	S	.	.	H	α-helix	trans	-62.4	-32.6	-174.3	-59.8	-59.8	-60.3	0	0	111.8	Y220 P225 L230 L231	Y220-Q227 VanDerWaalsContact OH-CD 3.25Å; Y220-Q227 PolarHBondContact OH-NE2 2.63Å; Y220-Q227 PolarHBondContact OH-OE1 3.33Å; P225-Q227 PolarHBondContact O-N 2.76Å; P225-Q227 PolarHBondContact O-NE2 3.42Å; Q227-L230 PolarHBondContact O-N 2.91Å; Q227-L231 WeakPolarHBondContact O-CB 3.49Å; Q227-L231 VanDerWaalsContact O-CG 3.29Å; Q227-L231 WeakPolarHBondContact O-CG 3.15Å; Q227-L231 PolarHBondContact O-N 3.37Å
228	L	93.1	Very high	90.2	Very high	130 Å²	130	76.1 Å²	76.1	68%	0.681	39%	0.385	S	S	*	.	H	α-helix	trans	-69.8	-45.2	-179.4	-176.8	62.6	0	0	0	111	D226 L230 R232	D226-L228 PolarHBondContact O-N 3.25Å; D226-L228 PolarHBondContact OD1-N 2.9Å; L228-L230 VanDerWaalsContact C-N 3.32Å; L228-L230 PolarHBondContact O-N 3Å; L228-R232 VanDerWaalsContact O-CB 3.28Å; L228-R232 WeakPolarHBondContact O-CB 3.11Å; L228-R232 PolarHBondContact O-N 3.14Å
229	S	92.2	Very high	90	Very high	53 Å²	53	71.5 Å²	71.5	37%	0.371	37%	0.372	S	S	.	.	H	α-helix	trans	-65	-36.2	175.6	-65.8	0	0	0	0	112.4	D226 R232 G233	D226-S229 PolarHBondContact O-N 2.99Å; D226-S229 WeakPolarHBondContact OD2-CB 3.35Å; D226-S229 PolarHBondContact OD2-N 3.1Å; D226-S229 VanDerWaalsContact OD2-N 3.09Å; D226-S229 PolarHBondContact OD2-OG 3.35Å; S229-R232 PolarHBondContact O-N 3.35Å; S229-G233 PolarHBondContact O-N 3.08Å
230	L	92.5	Very high	89.8	Confident	6 Å²	6	75 Å²	75	3%	0.031	40%	0.396	C	S	.	.	H	α-helix	trans	-64.7	-51.8	175.5	-172.7	160.9	0	0	0	111.6	L99 Y220 D226 Q227 L228 R232 G233 L234 I306 S310	L99-L230 HydrophobicContact CD1-CD2 4.28Å; L99-L230 HydrophobicContact CD1-CG 3.79Å; Y220-L230 HydrophobicContact CE2-CD1 3.68Å; Y220-L230 VanDerWaalsContact OH-CD1 3.25Å; Y220-L230 WeakPolarHBondContact OH-CD1 3.45Å; D226-L230 PolarHBondContact O-N 3.41Å; Q227-L230 PolarHBondContact O-N 2.91Å; L228-L230 VanDerWaalsContact C-N 3.32Å; L228-L230 PolarHBondContact O-N 3Å; L230-R232 VanDerWaalsContact C-N 3.27Å; L230-R232 PolarHBondContact O-N 3.29Å; L230-G233 CarbonylContact O-C 3.3Å; L230-G233 PolarHBondContact O-N 3.04Å; L230-G233 VanDerWaalsContact O-N 3.11Å; L230-L234 WeakPolarHBondContact O-CB 3.1Å; L230-L234 PolarHBondContact O-N 3.47Å; L230-I306 HydrophobicContact CD1-CG2 4.35Å; L230-I306 HydrophobicContact CD2-CG2 4.24Å; L230-S310 WeakPolarHBondContact CD1-OG 3.38Å
231	L	93.3	Very high	89.2	Confident	91 Å²	91	77.3 Å²	77.3	48%	0.476	43%	0.428	S	S	.	.	H	α-helix	trans	-60.7	-38.7	177.3	-73.1	172.9	0	0	0	111.7	Q227 L234 F235	Q227-L231 WeakPolarHBondContact O-CB 3.49Å; Q227-L231 VanDerWaalsContact O-CG 3.29Å; Q227-L231 WeakPolarHBondContact O-CG 3.15Å; Q227-L231 PolarHBondContact O-N 3.37Å; L231-L234 PolarHBondContact O-N 2.82Å; L231-F235 HydrophobicContact CD2-CE2 4.15Å; L231-F235 WeakPolarHBondContact O-CD2 3.4Å; L231-F235 PolarHBondContact O-N 2.86Å; L231-F235 VanDerWaalsContact O-N 3.14Å
232	R	92.8	Very high	88.8	Confident	181 Å²	181	73.8 Å²	73.8	68%	0.683	41%	0.413	S	S	*	.	H	α-helix	trans	-63.2	-46.4	173.7	-172.6	177.3	-177.3	166.1	1.5	111.1	L228 S229 L230 L234 V236	L228-R232 VanDerWaalsContact O-CB 3.28Å; L228-R232 WeakPolarHBondContact O-CB 3.11Å; L228-R232 PolarHBondContact O-N 3.14Å; S229-R232 PolarHBondContact O-N 3.35Å; L230-R232 VanDerWaalsContact C-N 3.27Å; L230-R232 PolarHBondContact O-N 3.29Å; R232-L234 VanDerWaalsContact C-N 3.26Å; R232-L234 PolarHBondContact O-N 3.19Å; R232-V236 HydrophobicContact CG-CB 4.32Å; R232-V236 HydrophobicContact CG-CG2 3.97Å; R232-V236 WeakPolarHBondContact O-CA 3.41Å; R232-V236 WeakPolarHBondContact O-CB 3.3Å; R232-V236 WeakPolarHBondContact O-CG2 3.23Å; R232-V236 PolarHBondContact O-N 2.66Å
233	G	91.8	Very high	88.6	Confident	10 Å²	10	72.6 Å²	72.6	10%	0.103	41%	0.413	C	S	.	.	H	α-helix	trans	-62.4	-31.5	177.2	0	0	0	0	0	113.7	Y96 W100 S229 L230	Y96-G233 WeakPolarHBondContact O-CA 3.39Å; W100-G233 WeakPolarHBondContact CB-O 3.48Å; W100-G233 PolarHBondContact N-O 3.43Å; S229-G233 PolarHBondContact O-N 3.08Å; L230-G233 CarbonylContact O-C 3.3Å; L230-G233 PolarHBondContact O-N 3.04Å; L230-G233 VanDerWaalsContact O-N 3.11Å
234	L	92.5	Very high	88.2	Confident	19 Å²	19	79 Å²	79	10%	0.099	43%	0.433	C	S	.	.	H	α-helix	trans	-77.6	-38.1	-178.6	-170.6	67	0	0	0	113.3	L99 W100 L103 L230 L231 R232 I306	L99-L234 HydrophobicContact CB-CB 4.38Å; L99-L234 HydrophobicContact CB-CD1 4.18Å; W100-L234 VanDerWaalsContact CA-O 3.26Å; W100-L234 WeakPolarHBondContact CA-O 3.26Å; W100-L234 WeakPolarHBondContact CB-O 3.48Å; L103-L234 HydrophobicContact CB-CD1 3.83Å; L103-L234 HydrophobicContact CD2-CD1 4.11Å; L103-L234 HydrophobicContact CD2-CG 4.07Å; L103-L234 HydrophobicContact CG-CD1 4.41Å; L230-L234 WeakPolarHBondContact O-CB 3.1Å; L230-L234 PolarHBondContact O-N 3.47Å; L231-L234 PolarHBondContact O-N 2.82Å; R232-L234 VanDerWaalsContact C-N 3.26Å; R232-L234 PolarHBondContact O-N 3.19Å; L234-I306 HydrophobicContact CD1-CD1 3.94Å; L234-I306 HydrophobicContact CD1-CG1 4.46Å; L234-I306 HydrophobicContact CD2-CD1 4.27Å
235	F	92.5	Very high	87.9	Confident	142 Å²	142	74.2 Å²	74.2	62%	0.623	42%	0.42	S	S	*	.	H	α-helix	trans	-108	-16.6	-173.9	-67.1	-67.9	0	0	0	114.9	L103 L231 P237	L103-F235 HydrophobicContact CD2-CD1 4.38Å; L103-F235 HydrophobicContact CD2-CE1 4.22Å; L231-F235 HydrophobicContact CD2-CE2 4.15Å; L231-F235 WeakPolarHBondContact O-CD2 3.4Å; L231-F235 PolarHBondContact O-N 2.86Å; L231-F235 VanDerWaalsContact O-N 3.14Å; F235-P237 WeakPolarHBondContact O-CD 3.21Å
236	V	90.5	Very high	87.8	Confident	66 Å²	66	75.3 Å²	75.3	40%	0.4	42%	0.424	S	S	.	.			trans	-103.8	111.2	-179	-174.3	0	0	0	0	109.6	R232 S238	R232-V236 HydrophobicContact CG-CB 4.32Å; R232-V236 HydrophobicContact CG-CG2 3.97Å; R232-V236 WeakPolarHBondContact O-CA 3.41Å; R232-V236 WeakPolarHBondContact O-CB 3.3Å; R232-V236 WeakPolarHBondContact O-CG2 3.23Å; R232-V236 PolarHBondContact O-N 2.66Å; V236-S238 VanDerWaalsContact C-N 3.25Å; V236-S238 PolarHBondContact O-N 3.29Å
237	P	87.2	Confident	87.3	Confident	96 Å²	96	75.3 Å²	75.3	62%	0.623	42%	0.424	S	S	*	.			trans	-73.6	80	176.4	31.2	-34.7	0	0	0	110.3	W100 F235	W100-P237 HydrophobicContact CD2-CB 3.77Å; W100-P237 HydrophobicContact CE3-CB 3.78Å; W100-P237 HydrophobicContact CG-CB 4.24Å; W100-P237 HydrophobicContact CH2-CB 4.49Å; W100-P237 HydrophobicContact CZ2-CB 4.49Å; W100-P237 HydrophobicContact CZ3-CB 4.15Å; F235-P237 WeakPolarHBondContact O-CD 3.21Å
238	S	83.4	Confident	86.6	Confident	63 Å²	63	74.6 Å²	74.6	44%	0.441	42%	0.42	S	S	.	.			trans	-143.8	128.3	179.4	-171	0	0	0	0	110.5	V236 P240	V236-S238 VanDerWaalsContact C-N 3.25Å; V236-S238 PolarHBondContact O-N 3.29Å; S238-P240 VanDerWaalsContact C-CD 3.47Å; S238-P240 WeakPolarHBondContact O-CD 3.21Å
239	C	83.3	Confident	86.2	Confident	44 Å²	44	69 Å²	69	30%	0.297	39%	0.39	S	S	.	.			trans	-122.8	72.6	175.7	-149.2	0	0	0	0	108.5	G241 C242	C239-G241 PolarHBondContact O-N 3.02Å; C239-C242 WeakPolarHBondContact CA-SG 3.06Å; C239-C242 HydrophobicContact CB-CB 3.74Å; C239-C242 WeakPolarHBondContact CB-SG 3.5Å; C239-C242 PolarHBondContact O-N 3.4Å; C239-C242 PolarHBondContact O-SG 3.34Å; C239-C242 VanDerWaalsContact O-SG 3.38Å; C239-C242 WeakPolarHBondContact SG-CB 3.24Å; C239-C242 CovalentContact SG-SG 2Å; C239-C242 PolarHBondContact SG-SG 3.46Å
240	P	81.2	Confident	85.8	Confident	77 Å²	77	67.1 Å²	67.1	50%	0.5	38%	0.379	S	S	.	.	T	Hydrogen-bonded Turn	trans	-68	122.3	-176.6	27.4	-32.9	0	0	0	110.2	R97 S238 C242	R97-P240 VanDerWaalsContact CZ-O 3.28Å; R97-P240 PolarHBondContact NH1-O 3.45Å; S238-P240 VanDerWaalsContact C-CD 3.47Å; S238-P240 WeakPolarHBondContact O-CD 3.21Å; P240-C242 VanDerWaalsContact C-N 3.33Å
241	G	79.3	Confident	85.2	Confident	77 Å²	77	67.1 Å²	67.1	79%	0.794	38%	0.379	S	S	*	.	T	Hydrogen-bonded Turn	trans	75.5	16.5	178.5	0	0	0	0	0	114.9	C239 G243	C239-G241 PolarHBondContact O-N 3.02Å; G241-G243 PolarHBondContact O-N 2.95Å
242	C	82.4	Confident	84.7	Confident	42 Å²	42	63 Å²	63	28%	0.284	36%	0.358	S	S	.	.			trans	-70.4	127.3	176.4	-65.5	0	0	0	0	110.8	C239 P240 E246	C239-C242 WeakPolarHBondContact CA-SG 3.06Å; C239-C242 HydrophobicContact CB-CB 3.74Å; C239-C242 WeakPolarHBondContact CB-SG 3.5Å; C239-C242 PolarHBondContact O-N 3.4Å; C239-C242 PolarHBondContact O-SG 3.34Å; C239-C242 VanDerWaalsContact O-SG 3.38Å; C239-C242 WeakPolarHBondContact SG-CB 3.24Å; C239-C242 CovalentContact SG-SG 2Å; C239-C242 PolarHBondContact SG-SG 3.46Å; P240-C242 VanDerWaalsContact C-N 3.33Å; C242-E246 HydrophobicContact CB-CB 3.75Å; C242-E246 HydrophobicContact CB-CG 4.04Å
243	G	83.6	Confident	84.5	Confident	36 Å²	36	54.4 Å²	54.4	37%	0.371	33%	0.326	S	S	.	.			trans	-99.1	-151.6	178.9	0	0	0	0	0	112	G241 E246 L247	G241-G243 PolarHBondContact O-N 2.95Å; G243-E246 WeakPolarHBondContact CA-OE2 3.17Å; G243-E246 PolarHBondContact N-OE2 3.31Å; G243-L247 PolarHBondContact O-N 2.94Å
244	W	79.5	Confident	84.1	Confident	174 Å²	174	54.8 Å²	54.8	66%	0.659	33%	0.325	S	S	*	.	H	α-helix	trans	-66.3	-46	179.7	-66.6	116	0	0	0	114	E246 L247 E248 F500	W244-E246 PolarHBondContact O-N 2.83Å; W244-L247 HydrophobicContact CE3-CD2 4.29Å; W244-L247 HydrophobicContact CZ3-CD2 4.08Å; W244-L247 PolarHBondContact O-N 3.35Å; W244-E248 PolarHBondContact O-N 3.14Å; W244-F500 HydrophobicContact CE3-CE1 4.05Å; W244-F500 AromaticContact CE3-CZ 3.86Å; W244-F500 HydrophobicContact CE3-CZ 3.86Å; W244-F500 HydrophobicContact CH2-CE1 4.34Å; W244-F500 AromaticContact CH2-CE2 3.96Å; W244-F500 HydrophobicContact CH2-CE2 3.96Å; W244-F500 AromaticContact CH2-CZ 3.43Å; W244-F500 HydrophobicContact CH2-CZ 3.43Å; W244-F500 VanDerWaalsContact CH2-CZ 3.43Å; W244-F500 AromaticContact CZ3-CE1 3.49Å; W244-F500 HydrophobicContact CZ3-CE1 3.49Å; W244-F500 VanDerWaalsContact CZ3-CE1 3.49Å; W244-F500 AromaticContact CZ3-CE2 3.92Å; W244-F500 HydrophobicContact CZ3-CE2 3.92Å; W244-F500 AromaticContact CZ3-CZ 3Å; W244-F500 HydrophobicContact CZ3-CZ 3Å
245	P	81.7	Confident	83.7	Confident	71 Å²	71	53.9 Å²	53.9	46%	0.461	32%	0.321	S	S	.	.	H	α-helix	trans	-62.5	-40.9	-178.4	-23	35.4	0	0	0	112.8	I93 L247 E248 Q249	I93-P245 HydrophobicContact CG2-CB 3.84Å; P245-L247 VanDerWaalsContact C-N 3.32Å; P245-L247 PolarHBondContact O-N 3.32Å; P245-E248 PolarHBondContact O-N 3.35Å; P245-Q249 WeakPolarHBondContact O-CB 3.4Å; P245-Q249 PolarHBondContact O-N 3.4Å
246	E	86.8	Confident	83.5	Confident	30 Å²	30	47.1 Å²	47.1	14%	0.14	29%	0.291	C	S	.	.	H	α-helix	trans	-66.1	-36.3	177.9	-63.5	85	161.7	0	0	111.9	I93 A94 C242 G243 W244 A250	I93-E246 HydrophobicContact CG2-CG 4.03Å; A94-E246 HydrophobicContact CB-CG 4.08Å; C242-E246 HydrophobicContact CB-CB 3.75Å; C242-E246 HydrophobicContact CB-CG 4.04Å; G243-E246 WeakPolarHBondContact CA-OE2 3.17Å; G243-E246 PolarHBondContact N-OE2 3.31Å; W244-E246 PolarHBondContact O-N 2.83Å; E246-A250 WeakPolarHBondContact O-CB 3.22Å; E246-A250 PolarHBondContact O-N 3.08Å
247	L	81	Confident	83.5	Confident	84 Å²	84	44 Å²	44	44%	0.44	27%	0.272	S	S	.	.	H	α-helix	trans	-70	-43.3	176.7	-176.1	65.5	0	0	0	111.1	G243 W244 P245 Q249 A250 V251 F500	G243-L247 PolarHBondContact O-N 2.94Å; W244-L247 HydrophobicContact CE3-CD2 4.29Å; W244-L247 HydrophobicContact CZ3-CD2 4.08Å; W244-L247 PolarHBondContact O-N 3.35Å; P245-L247 VanDerWaalsContact C-N 3.32Å; P245-L247 PolarHBondContact O-N 3.32Å; L247-Q249 VanDerWaalsContact C-N 3.32Å; L247-Q249 PolarHBondContact O-N 2.9Å; L247-A250 WeakPolarHBondContact O-CB 3.08Å; L247-A250 PolarHBondContact O-N 3.25Å; L247-V251 WeakPolarHBondContact O-CG2 2.95Å; L247-V251 PolarHBondContact O-N 3.08Å; L247-F500 HydrophobicContact CD2-CE1 4.44Å
248	E	77.9	Confident	83.5	Confident	74 Å²	74	39.6 Å²	39.6	35%	0.346	24%	0.244	S	C	.	.	H	α-helix	trans	-58.6	-46	174.8	-175.7	168.9	-176.2	0	0	110.8	W244 P245 A250 V251 G252 L501	W244-E248 PolarHBondContact O-N 3.14Å; P245-E248 PolarHBondContact O-N 3.35Å; E248-A250 VanDerWaalsContact C-N 3.34Å; E248-A250 PolarHBondContact O-N 3.39Å; E248-V251 WeakPolarHBondContact O-CB 3.27Å; E248-V251 PolarHBondContact O-N 2.62Å; E248-V251 VanDerWaalsContact O-N 3.16Å; E248-G252 PolarHBondContact O-N 3.31Å; E248-L501 HydrophobicContact CG-CD2 4.24Å
249	Q	85.5	Confident	83.9	Confident	12 Å²	12	36.7 Å²	36.7	6%	0.056	22%	0.223	C	C	.	.	H	α-helix	trans	-62.7	-39.3	176.1	-163.8	61.3	29.9	0	0	112.7	S86 L98 P245 L247 V251 G252 I253	S86-Q249 PolarHBondContact O-NE2 2.57Å; L98-Q249 HydrophobicContact CD1-CB 4.08Å; L98-Q249 HydrophobicContact CD1-CG 4.17Å; P245-Q249 WeakPolarHBondContact O-CB 3.4Å; P245-Q249 PolarHBondContact O-N 3.4Å; L247-Q249 VanDerWaalsContact C-N 3.32Å; L247-Q249 PolarHBondContact O-N 2.9Å; Q249-V251 PolarHBondContact O-N 2.87Å; Q249-G252 WeakPolarHBondContact O-CA 3.43Å; Q249-G252 PolarHBondContact O-N 3.01Å; Q249-I253 WeakPolarHBondContact O-CG1 3.33Å; Q249-I253 PolarHBondContact O-N 2.83Å
250	A	83.7	Confident	84.2	Confident	15 Å²	15	34.8 Å²	34.8	12%	0.124	21%	0.21	C	C	.	.	H	α-helix	trans	-57.6	-36.6	176.8	0	0	0	0	0	112.1	L98 L101 E246 L247 E248	L98-A250 HydrophobicContact CD2-CB 3.95Å; L101-A250 HydrophobicContact CD2-CB 3.51Å; L101-A250 VanDerWaalsContact CD2-O 3.25Å; L101-A250 WeakPolarHBondContact CD2-O 3.45Å; E246-A250 WeakPolarHBondContact O-CB 3.22Å; E246-A250 PolarHBondContact O-N 3.08Å; L247-A250 WeakPolarHBondContact O-CB 3.08Å; L247-A250 PolarHBondContact O-N 3.25Å; E248-A250 VanDerWaalsContact C-N 3.34Å; E248-A250 PolarHBondContact O-N 3.39Å
251	V	79.3	Confident	84.8	Confident	5 Å²	5	31.1 Å²	31.1	3%	0.03	19%	0.187	C	C	.	.	H	α-helix	trans	-70.9	-44.1	173.8	-178.2	0	0	0	0	111.3	L247 E248 Q249 I253 L254 G255 I497 L501	L247-V251 WeakPolarHBondContact O-CG2 2.95Å; L247-V251 PolarHBondContact O-N 3.08Å; E248-V251 WeakPolarHBondContact O-CB 3.27Å; E248-V251 PolarHBondContact O-N 2.62Å; E248-V251 VanDerWaalsContact O-N 3.16Å; Q249-V251 PolarHBondContact O-N 2.87Å; V251-I253 VanDerWaalsContact C-N 3.27Å; V251-I253 PolarHBondContact O-N 3.38Å; V251-L254 PolarHBondContact O-N 2.85Å; V251-L254 VanDerWaalsContact O-N 3.1Å; V251-G255 PolarHBondContact O-N 3.34Å; V251-G255 VanDerWaalsContact O-N 3.11Å; V251-I497 HydrophobicContact CB-CG2 3.72Å; V251-I497 HydrophobicContact CG1-CG2 3.18Å; V251-I497 HydrophobicContact CG2-CB 4.27Å; V251-I497 HydrophobicContact CG2-CD1 4.24Å; V251-I497 HydrophobicContact CG2-CG1 4.25Å; V251-I497 HydrophobicContact CG2-CG2 3.12Å; V251-L501 HydrophobicContact CB-CD1 3.92Å; V251-L501 HydrophobicContact CG1-CD1 3.52Å; V251-L501 HydrophobicContact CG2-CD1 4.09Å
252	G	82.6	Confident	85.5	Confident	5 Å²	5	27.5 Å²	27.5	5%	0.052	15%	0.149	C	C	.	.	H	α-helix	trans	-51.9	-46.7	176	0	0	0	0	0	111.7	E248 Q249 L254 G255 A256	E248-G252 PolarHBondContact O-N 3.31Å; Q249-G252 WeakPolarHBondContact O-CA 3.43Å; Q249-G252 PolarHBondContact O-N 3.01Å; G252-L254 VanDerWaalsContact C-N 3.34Å; G252-L254 PolarHBondContact O-N 3.49Å; G252-G255 PolarHBondContact O-N 3.09Å; G252-A256 VanDerWaalsContact O-CB 3.27Å; G252-A256 WeakPolarHBondContact O-CB 3.25Å; G252-A256 PolarHBondContact O-N 3.29Å
253	I	88.5	Confident	86	Confident	0 Å²	0	25.5 Å²	25.5	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-56.5	-45.2	177.1	-66	166.4	0	0	0	111.4	S86 L98 L102 Q249 V251 A256 V257	S86-I253 WeakPolarHBondContact OG-CA 3.46Å; L98-I253 HydrophobicContact CB-CD1 3.78Å; L98-I253 HydrophobicContact CD1-CD1 3.89Å; L98-I253 HydrophobicContact CG-CD1 4.4Å; L102-I253 HydrophobicContact CB-CG2 4.25Å; L102-I253 HydrophobicContact CD1-CG2 4.22Å; Q249-I253 WeakPolarHBondContact O-CG1 3.33Å; Q249-I253 PolarHBondContact O-N 2.83Å; V251-I253 VanDerWaalsContact C-N 3.27Å; V251-I253 PolarHBondContact O-N 3.38Å; I253-A256 PolarHBondContact O-N 2.93Å; I253-V257 HydrophobicContact CG2-CG2 4.12Å; I253-V257 VanDerWaalsContact O-CB 3.26Å; I253-V257 WeakPolarHBondContact O-CB 2.96Å; I253-V257 WeakPolarHBondContact O-CG2 3.37Å; I253-V257 PolarHBondContact O-N 3.31Å
254	L	83.7	Confident	86.6	Confident	18 Å²	18	23.8 Å²	23.8	9%	0.094	12%	0.118	C	C	.	.	H	α-helix	trans	-65.8	-41.4	-179.2	-175.5	64.9	0	0	0	111.9	A105 V251 G252 V258 V494	A105-L254 HydrophobicContact CB-CD1 4.1Å; V251-L254 PolarHBondContact O-N 2.85Å; V251-L254 VanDerWaalsContact O-N 3.1Å; G252-L254 VanDerWaalsContact C-N 3.34Å; G252-L254 PolarHBondContact O-N 3.49Å; L254-V258 HydrophobicContact CD1-CG2 4.16Å; L254-V258 WeakPolarHBondContact O-CB 3.32Å; L254-V258 PolarHBondContact O-N 3.06Å; L254-V258 VanDerWaalsContact O-N 3.11Å; L254-V494 HydrophobicContact CD2-CG2 3.5Å; L254-V494 VanDerWaalsContact CD2-CG2 3.5Å; L254-V494 HydrophobicContact CG-CG2 4.48Å
255	G	83.3	Confident	87.3	Confident	0 Å²	0	15.5 Å²	15.5	0%	0	9%	0.086	C	C	.	.	H	α-helix	trans	-69.1	-38.7	177.9	0	0	0	0	0	113.3	V251 G252 M442	V251-G255 PolarHBondContact O-N 3.34Å; V251-G255 VanDerWaalsContact O-N 3.11Å; G252-G255 PolarHBondContact O-N 3.09Å; G255-M442 WeakPolarHBondContact O-CB 3.45Å
256	A	88.5	Confident	87.9	Confident	1 Å²	1	12.1 Å²	12.1	1%	0.008	6%	0.064	C	C	.	.	H	α-helix	trans	-69.8	-45	178.2	0	0	0	0	0	111.9	N83 G252 I253 M259	N83-A256 HydrophobicContact CB-CB 4.47Å; G252-A256 VanDerWaalsContact O-CB 3.27Å; G252-A256 WeakPolarHBondContact O-CB 3.25Å; G252-A256 PolarHBondContact O-N 3.29Å; I253-A256 PolarHBondContact O-N 2.93Å; A256-M259 WeakPolarHBondContact O-CG 3.43Å
257	V	91.2	Very high	88.3	Confident	0 Å²	0	10.7 Å²	10.7	0%	0	6%	0.058	C	C	.	.	H	α-helix	trans	-75	-36.8	-176.8	173.9	0	0	0	0	112.2	Y78 L102 A105 I253	Y78-V257 HydrophobicContact CD1-CG1 3.8Å; Y78-V257 WeakPolarHBondContact CD1-O 3.46Å; Y78-V257 HydrophobicContact CE1-CG1 3.58Å; Y78-V257 WeakPolarHBondContact CE1-O 2.88Å; Y78-V257 VanDerWaalsContact CZ-O 3.28Å; L102-V257 HydrophobicContact CD1-CG2 3.73Å; A105-V257 HydrophobicContact CB-CB 4.06Å; A105-V257 HydrophobicContact CB-CG1 3.85Å; A105-V257 HydrophobicContact CB-CG2 4.42Å; I253-V257 HydrophobicContact CG2-CG2 4.12Å; I253-V257 VanDerWaalsContact O-CB 3.26Å; I253-V257 WeakPolarHBondContact O-CB 2.96Å; I253-V257 WeakPolarHBondContact O-CG2 3.37Å; I253-V257 PolarHBondContact O-N 3.31Å
258	V	88.3	Confident	88.9	Confident	3 Å²	3	7 Å²	7	2%	0.018	4%	0.039	C	C	.	.	S	Bend	trans	-107.1	74.8	-174.5	-169.6	0	0	0	0	110.9	L112 L254 F263 L446	L112-V258 HydrophobicContact CD1-CG1 3.93Å; L254-V258 HydrophobicContact CD1-CG2 4.16Å; L254-V258 WeakPolarHBondContact O-CB 3.32Å; L254-V258 PolarHBondContact O-N 3.06Å; L254-V258 VanDerWaalsContact O-N 3.11Å; V258-F263 HydrophobicContact CG1-CE2 4.26Å; V258-F263 HydrophobicContact CG1-CZ 3.57Å; V258-L446 HydrophobicContact CB-CD1 3.79Å; V258-L446 HydrophobicContact CG1-CD1 3.68Å; V258-L446 HydrophobicContact CG1-CG 4.32Å
259	M	90	Very high	89.5	Confident	2 Å²	2	3.7 Å²	3.7	1%	0.01	2%	0.024	C	C	.	.			trans	-73	124.4	-177.7	-63.9	-175.6	117.1	0	0	113.3	A77 D80 S154 A256 H261 N262 M442	A77-M259 HydrophobicContact CB-SD 3.44Å; A77-M259 WeakPolarHBondContact CB-SD 3.5Å; D80-M259 WeakPolarHBondContact OD2-CE 3.34Å; S154-M259 WeakPolarHBondContact OG-CE 3.37Å; A256-M259 WeakPolarHBondContact O-CG 3.43Å; M259-H261 PolarHBondContact O-N 3.48Å; M259-H261 PolarHBondContact SD-CE1 3.42Å; M259-N262 HydrophobicContact CB-CB 4.06Å; M259-N262 WeakPolarHBondContact O-CB 3.34Å; M259-N262 PolarHBondContact O-N 3.25Å; M259-M442 HydrophobicContact CB-CE 3.96Å; M259-M442 HydrophobicContact CE-CE 3.9Å; M259-M442 HydrophobicContact CG-CE 3.97Å
260	P	90.3	Very high	89.8	Confident	4 Å²	4	3.1 Å²	3.1	3%	0.026	2%	0.021	C	C	.	.	H	α-helix	trans	-65.6	-38.4	-175.2	-21.9	33.8	0	0	0	113.8	N262 F263 Y264 M442 Q445 L446 A449	P260-N262 PolarHBondContact O-N 3.42Å; P260-F263 PolarHBondContact O-N 3.5Å; P260-Y264 WeakPolarHBondContact O-CD2 3.5Å; P260-M442 VanDerWaalsContact CD-CE 3.48Å; P260-Q445 HydrophobicContact CG-CB 3.87Å; P260-L446 HydrophobicContact CG-CB 4.35Å; P260-A449 HydrophobicContact CB-CB 3.72Å; P260-A449 WeakPolarHBondContact O-CB 3.48Å
261	H	92.9	Very high	90.1	Very high	1 Å²	1	4.1 Å²	4.1	1%	0.005	2%	0.023	C	C	.	.	H	α-helix	trans	-64.3	-29.2	-179.3	72.3	-104.2	0	0	0	111.8	I151 S154 M259 F263 Y264 L265 S389	I151-H261 HydrophobicContact CG1-CB 3.68Å; S154-H261 PolarHBondContact OG-CE1 2.92Å; M259-H261 PolarHBondContact O-N 3.48Å; M259-H261 PolarHBondContact SD-CE1 3.42Å; H261-F263 VanDerWaalsContact C-N 3.27Å; H261-F263 PolarHBondContact O-N 3.29Å; H261-Y264 WeakPolarHBondContact O-CB 3.47Å; H261-Y264 PolarHBondContact O-N 3.39Å; H261-Y264 VanDerWaalsContact O-N 3.08Å; H261-L265 PolarHBondContact O-N 3.3Å; H261-L265 VanDerWaalsContact O-N 3.15Å; H261-S389 PolarHBondContact CD2-OG 3.4Å
262	N	94.4	Very high	90.3	Very high	0 Å²	0	4.1 Å²	4.1	0%	0	2%	0.023	C	C	.	.	H	α-helix	trans	-68.7	-24.5	-175.1	-161.2	14.8	0	0	0	112.3	M74 A77 Q113 M259 P260 L265 H266	M74-N262 WeakPolarHBondContact CG-OD1 3.36Å; M74-N262 PolarHBondContact O-ND2 3.49Å; A77-N262 HydrophobicContact CB-CB 4.15Å; A77-N262 WeakPolarHBondContact CB-ND2 3.44Å; Q113-N262 PolarHBondContact NE2-ND2 2.93Å; M259-N262 HydrophobicContact CB-CB 4.06Å; M259-N262 WeakPolarHBondContact O-CB 3.34Å; M259-N262 PolarHBondContact O-N 3.25Å; P260-N262 PolarHBondContact O-N 3.42Å; N262-L265 WeakPolarHBondContact O-CB 3.26Å; N262-L265 PolarHBondContact O-N 3.15Å; N262-H266 WeakPolarHBondContact O-CB 3.42Å; N262-H266 PolarHBondContact O-N 3.36Å
263	F	94.3	Very high	90.4	Very high	0 Å²	0	3.9 Å²	3.9	0%	0	2%	0.021	C	C	.	.	H	α-helix	trans	-67.6	-37.1	171.8	-57	-41.5	0	0	0	112.4	L112 Q113 A116 L127 V258 P260 H261 S267 A449 V450 L453	L112-F263 HydrophobicContact CB-CD1 4.32Å; L112-F263 HydrophobicContact CB-CE1 3.47Å; L112-F263 VanDerWaalsContact CB-CE1 3.47Å; L112-F263 HydrophobicContact CB-CZ 3.64Å; L112-F263 HydrophobicContact CD1-CE1 4.33Å; L112-F263 HydrophobicContact CD1-CE2 4.35Å; L112-F263 HydrophobicContact CD1-CZ 3.63Å; L112-F263 HydrophobicContact CG-CZ 4.24Å; Q113-F263 HydrophobicContact CG-CD1 4.45Å; Q113-F263 HydrophobicContact CG-CE1 4.25Å; A116-F263 HydrophobicContact CB-CB 4.22Å; A116-F263 HydrophobicContact CB-CD1 4.47Å; L127-F263 HydrophobicContact CD2-CB 4.35Å; V258-F263 HydrophobicContact CG1-CE2 4.26Å; V258-F263 HydrophobicContact CG1-CZ 3.57Å; P260-F263 PolarHBondContact O-N 3.5Å; H261-F263 VanDerWaalsContact C-N 3.27Å; H261-F263 PolarHBondContact O-N 3.29Å; F263-S267 WeakPolarHBondContact O-CB 3.49Å; F263-S267 PolarHBondContact O-N 2.83Å; F263-S267 VanDerWaalsContact O-N 3.15Å; F263-S267 PolarHBondContact O-OG 3.22Å; F263-S267 VanDerWaalsContact O-OG 3.1Å; F263-A449 HydrophobicContact CD2-CB 3.71Å; F263-A449 HydrophobicContact CE2-CB 4.37Å; F263-V450 HydrophobicContact CD2-CG2 4.44Å; F263-V450 HydrophobicContact CE2-CG2 3.65Å; F263-V450 HydrophobicContact CZ-CG2 4.29Å; F263-L453 HydrophobicContact CB-CD2 4.46Å; F263-L453 HydrophobicContact CD1-CD2 4.42Å; F263-L453 HydrophobicContact CG-CD2 4.24Å
264	Y	94.7	Very high	90.2	Very high	0 Å²	0	7.5 Å²	7.5	0%	0	4%	0.04	C	C	.	.	H	α-helix	trans	-67.8	-42.8	175	-61.9	-86.2	0	0	0	110.4	L127 A128 V147 P260 H261 S267 A268 F397 F448 A449	L127-Y264 HydrophobicContact CB-CD1 3.84Å; L127-Y264 HydrophobicContact CB-CE1 4.08Å; L127-Y264 HydrophobicContact CD2-CD1 3.91Å; L127-Y264 HydrophobicContact CD2-CE1 3.63Å; L127-Y264 HydrophobicContact CD2-CE2 4.35Å; L127-Y264 HydrophobicContact CD2-CG 4.38Å; L127-Y264 HydrophobicContact CG-CD1 3.9Å; L127-Y264 HydrophobicContact CG-CE1 3.61Å; A128-Y264 HydrophobicContact CB-CD1 3.86Å; A128-Y264 HydrophobicContact CB-CE1 4.24Å; V147-Y264 HydrophobicContact CB-CE2 4.41Å; V147-Y264 HydrophobicContact CG1-CD2 4.01Å; V147-Y264 HydrophobicContact CG1-CE2 3.99Å; V147-Y264 HydrophobicContact CG2-CD2 4.29Å; V147-Y264 HydrophobicContact CG2-CE1 4.44Å; V147-Y264 HydrophobicContact CG2-CE2 3.44Å; V147-Y264 VanDerWaalsContact CG2-CE2 3.44Å; V147-Y264 WeakPolarHBondContact CG2-OH 3.02Å; P260-Y264 WeakPolarHBondContact O-CD2 3.5Å; H261-Y264 WeakPolarHBondContact O-CB 3.47Å; H261-Y264 PolarHBondContact O-N 3.39Å; H261-Y264 VanDerWaalsContact O-N 3.08Å; Y264-S267 PolarHBondContact O-OG 2.88Å; Y264-A268 PolarHBondContact O-N 3.43Å; Y264-F397 HydrophobicContact CD1-CE2 4.14Å; Y264-F397 AromaticContact CE1-CE2 3.54Å; Y264-F397 HydrophobicContact CE1-CE2 3.54Å; Y264-F397 AromaticContact CE1-CZ 3.59Å; Y264-F397 HydrophobicContact CE1-CZ 3.59Å; Y264-F397 AromaticContact CZ-CZ 3.95Å; Y264-F448 PolarHBondContact OH-O 3.39Å; Y264-A449 HydrophobicContact CE2-CB 3.67Å
265	L	93.8	Very high	90.2	Very high	1 Å²	1	7 Å²	7	1%	0.005	4%	0.037	C	C	.	.	H	α-helix	trans	-56.4	-58.4	174.7	-172.5	60.2	0	0	0	112	H261 N262 S267 A268 L269 T385 S389 F392	H261-L265 PolarHBondContact O-N 3.3Å; H261-L265 VanDerWaalsContact O-N 3.15Å; N262-L265 WeakPolarHBondContact O-CB 3.26Å; N262-L265 PolarHBondContact O-N 3.15Å; L265-S267 VanDerWaalsContact C-N 3.33Å; L265-S267 PolarHBondContact O-N 3.22Å; L265-A268 CarbonylContact O-C 3.55Å; L265-A268 WeakPolarHBondContact O-CA 3.41Å; L265-A268 WeakPolarHBondContact O-CB 3.46Å; L265-A268 PolarHBondContact O-N 3.4Å; L265-L269 HydrophobicContact CD1-CD1 3.96Å; L265-L269 HydrophobicContact CD1-CD2 4.37Å; L265-L269 HydrophobicContact CD1-CG 3.99Å; L265-L269 HydrophobicContact CD2-CD1 4.24Å; L265-L269 HydrophobicContact CG-CD1 3.68Å; L265-L269 HydrophobicContact CG-CG 4.09Å; L265-L269 WeakPolarHBondContact O-CG 3.4Å; L265-L269 PolarHBondContact O-N 3.4Å; L265-T385 HydrophobicContact CD2-CG2 3.86Å; L265-S389 WeakPolarHBondContact CB-OG 3.47Å; L265-F392 HydrophobicContact CD1-CD2 4.41Å; L265-F392 HydrophobicContact CD1-CE2 4.16Å
266	H	94.9	Very high	90.3	Very high	0 Å²	0	10.8 Å²	10.8	0%	0	6%	0.058	C	C	.	.	H	α-helix	trans	-64.7	-39.2	-172.5	-167.5	-170.1	0	0	0	111.8	M74 Q113 N262 A268 L269 V270 S294	M74-H266 HydrophobicContact CB-CB 4.24Å; M74-H266 HydrophobicContact CG-CB 3.86Å; Q113-H266 PolarHBondContact O-ND1 3.05Å; Q113-H266 VanDerWaalsContact OE1-CB 3.24Å; Q113-H266 PolarHBondContact OE1-ND1 3.32Å; N262-H266 WeakPolarHBondContact O-CB 3.42Å; N262-H266 PolarHBondContact O-N 3.36Å; H266-A268 PolarHBondContact O-N 3.41Å; H266-L269 PolarHBondContact O-N 3.45Å; H266-V270 WeakPolarHBondContact O-CG1 3.32Å; H266-V270 PolarHBondContact O-N 3.49Å; H266-S294 PolarHBondContact CE1-OG 2.92Å; H266-S294 PolarHBondContact NE2-OG 2.78Å
267	S	95.2	Very high	90.2	Very high	0 Å²	0	14.9 Å²	14.9	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-62.8	-22.9	174.2	72.3	0	0	0	0	113.8	A116 G120 L127 F263 Y264 L265 V270	A116-S267 WeakPolarHBondContact O-CA 3.24Å; A116-S267 WeakPolarHBondContact O-CB 3.44Å; G120-S267 WeakPolarHBondContact CA-O 3.41Å; L127-S267 PolarHBondContact N-OG 3.24Å; F263-S267 WeakPolarHBondContact O-CB 3.49Å; F263-S267 PolarHBondContact O-N 2.83Å; F263-S267 VanDerWaalsContact O-N 3.15Å; F263-S267 PolarHBondContact O-OG 3.22Å; F263-S267 VanDerWaalsContact O-OG 3.1Å; Y264-S267 PolarHBondContact O-OG 2.88Å; L265-S267 VanDerWaalsContact C-N 3.33Å; L265-S267 PolarHBondContact O-N 3.22Å; S267-V270 WeakPolarHBondContact O-CG2 3.46Å
268	A	93.4	Very high	89.9	Confident	5 Å²	5	22 Å²	22	4%	0.041	11%	0.111	C	C	.	.	H	α-helix	trans	-91.3	-40.8	175.7	0	0	0	0	0	112.8	H126 Y264 L265 H266 V270 K271 F392	H126-A268 HydrophobicContact CB-CB 3.66Å; Y264-A268 PolarHBondContact O-N 3.43Å; L265-A268 CarbonylContact O-C 3.55Å; L265-A268 WeakPolarHBondContact O-CA 3.41Å; L265-A268 WeakPolarHBondContact O-CB 3.46Å; L265-A268 PolarHBondContact O-N 3.4Å; H266-A268 PolarHBondContact O-N 3.41Å; A268-V270 VanDerWaalsContact C-N 3.28Å; A268-V270 PolarHBondContact O-N 2.87Å; A268-K271 VanDerWaalsContact O-CB 3.24Å; A268-K271 WeakPolarHBondContact O-CB 3.46Å; A268-K271 PolarHBondContact O-N 3.05Å; A268-F392 HydrophobicContact CB-CB 4.24Å; A268-F392 HydrophobicContact CB-CD1 3.72Å; A268-F392 HydrophobicContact CB-CD2 3.33Å; A268-F392 HydrophobicContact CB-CE1 3.79Å; A268-F392 HydrophobicContact CB-CE2 3.41Å; A268-F392 VanDerWaalsContact CB-CE2 3.41Å; A268-F392 HydrophobicContact CB-CG 3.49Å; A268-F392 VanDerWaalsContact CB-CG 3.49Å; A268-F392 HydrophobicContact CB-CZ 3.63Å
269	L	90.8	Very high	89.8	Confident	5 Å²	5	24.1 Å²	24.1	3%	0.026	12%	0.122	C	C	.	.	H	α-helix	trans	-60.7	-37.1	-179.2	-71.2	177.5	0	0	0	112	P70 L73 L265 H266 K271 S272	P70-L269 HydrophobicContact CB-CB 3.78Å; P70-L269 HydrophobicContact CG-CB 4.35Å; L73-L269 HydrophobicContact CB-CD1 3.56Å; L73-L269 HydrophobicContact CD1-CD1 4.01Å; L73-L269 HydrophobicContact CD1-CD2 4.11Å; L73-L269 HydrophobicContact CG-CD1 4.41Å; L265-L269 HydrophobicContact CD1-CD1 3.96Å; L265-L269 HydrophobicContact CD1-CD2 4.37Å; L265-L269 HydrophobicContact CD1-CG 3.99Å; L265-L269 HydrophobicContact CD2-CD1 4.24Å; L265-L269 HydrophobicContact CG-CD1 3.68Å; L265-L269 HydrophobicContact CG-CG 4.09Å; L265-L269 WeakPolarHBondContact O-CG 3.4Å; L265-L269 PolarHBondContact O-N 3.4Å; H266-L269 PolarHBondContact O-N 3.45Å; L269-K271 PolarHBondContact O-N 2.88Å; L269-K271 VanDerWaalsContact O-N 3.08Å; L269-S272 WeakPolarHBondContact O-CB 3.3Å; L269-S272 PolarHBondContact O-N 2.97Å; L269-S272 VanDerWaalsContact O-N 3.08Å; L269-S272 PolarHBondContact O-OG 3.21Å
270	V	91.7	Very high	89.7	Confident	1 Å²	1	26.8 Å²	26.8	1%	0.006	14%	0.14	C	C	.	.	G	3₁₀ helix	trans	-63	-15.1	176.5	-62.7	0	0	0	0	114.1	P70 A117 V121 H266 S267 A268 S272 Y290	P70-V270 HydrophobicContact CB-CG1 4.42Å; A117-V270 HydrophobicContact CB-CG1 3.93Å; V121-V270 HydrophobicContact CG2-CB 3.92Å; V121-V270 HydrophobicContact CG2-CG1 4.5Å; V121-V270 HydrophobicContact CG2-CG2 4Å; H266-V270 WeakPolarHBondContact O-CG1 3.32Å; H266-V270 PolarHBondContact O-N 3.49Å; S267-V270 WeakPolarHBondContact O-CG2 3.46Å; A268-V270 VanDerWaalsContact C-N 3.28Å; A268-V270 PolarHBondContact O-N 2.87Å; V270-S272 VanDerWaalsContact C-N 3.28Å; V270-S272 PolarHBondContact O-N 3.43Å; V270-Y290 HydrophobicContact CB-CD2 4.36Å; V270-Y290 HydrophobicContact CB-CE1 4.29Å; V270-Y290 HydrophobicContact CB-CE2 3.86Å; V270-Y290 HydrophobicContact CG1-CD1 3.99Å; V270-Y290 HydrophobicContact CG1-CD2 4.15Å; V270-Y290 HydrophobicContact CG1-CE1 3.96Å; V270-Y290 HydrophobicContact CG1-CE2 4.08Å; V270-Y290 HydrophobicContact CG1-CG 4.09Å; V270-Y290 PolarHBondContact O-OH 3.46Å
271	K	89.6	Confident	89.5	Confident	35 Å²	35	32 Å²	32	15%	0.152	16%	0.162	C	C	.	.	G	3₁₀ helix	trans	-75.2	-14.7	175.3	-63.1	172.6	61.3	179.3	0	113.4	G124 H126 E129 A268 L269 R273	G124-K271 WeakPolarHBondContact O-CE 3.35Å; H126-K271 HydrophobicContact CB-CD 4.26Å; E129-K271 IonicContact OE1-NZ 2.96Å; E129-K271 PolarHBondContact OE1-NZ 3.38Å; E129-K271 IonicContact OE2-NZ 2.78Å; E129-K271 PolarHBondContact OE2-NZ 2.86Å; A268-K271 VanDerWaalsContact O-CB 3.24Å; A268-K271 WeakPolarHBondContact O-CB 3.46Å; A268-K271 PolarHBondContact O-N 3.05Å; L269-K271 PolarHBondContact O-N 2.88Å; L269-K271 VanDerWaalsContact O-N 3.08Å; K271-R273 PolarHBondContact O-N 2.89Å
272	S	84.7	Confident	89.2	Confident	6 Å²	6	33 Å²	33	4%	0.042	17%	0.168	C	C	.	.	G	3₁₀ helix	trans	-70.5	-13.5	-178.6	57.2	0	0	0	0	114	K46 I47 L269 V270	K46-S272 WeakPolarHBondContact CA-O 3.31Å; I47-S272 PolarHBondContact N-O 3.15Å; L269-S272 WeakPolarHBondContact O-CB 3.3Å; L269-S272 PolarHBondContact O-N 2.97Å; L269-S272 VanDerWaalsContact O-N 3.08Å; L269-S272 PolarHBondContact O-OG 3.21Å; V270-S272 VanDerWaalsContact C-N 3.28Å; V270-S272 PolarHBondContact O-N 3.43Å
273	R	84.9	Confident	89	Confident	0 Å²	0	33.2 Å²	33.2	0%	0	17%	0.168	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-100.1	127.7	173.3	-70.2	58.5	178.6	166.6	9.1	108	V49 F67 T68 E202 K271 I275 Y290	V49-R273 HydrophobicContact CG2-CB 4Å; F67-R273 HydrophobicContact CD1-CB 4.41Å; F67-R273 HydrophobicContact CD1-CG 4.07Å; F67-R273 HydrophobicContact CE1-CB 4.18Å; F67-R273 HydrophobicContact CE1-CG 4.31Å; T68-R273 PolarHBondContact O-NH2 3.05Å; E202-R273 IonicContact OE1-CZ 2.88Å; E202-R273 IonicContact OE1-NH1 2.91Å; E202-R273 PolarHBondContact OE1-NH1 3.06Å; E202-R273 IonicContact OE1-NH2 3.95Å; E202-R273 PolarHBondContact OE1-NH2 3.42Å; E202-R273 IonicContact OE2-NH2 3.18Å; E202-R273 PolarHBondContact OE2-NH2 3.16Å; K271-R273 PolarHBondContact O-N 2.89Å; R273-I275 PolarHBondContact O-N 3.2Å; R273-Y290 VanDerWaalsContact CB-OH 3.29Å; R273-Y290 WeakPolarHBondContact CB-OH 3.17Å; R273-Y290 VanDerWaalsContact CD-OH 3.3Å; R273-Y290 WeakPolarHBondContact CD-OH 3.32Å; R273-Y290 WeakPolarHBondContact CG-OH 3.4Å
274	D	83.1	Confident	88.7	Confident	75 Å²	75	42 Å²	42	40%	0.401	20%	0.202	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-79.7	114.8	-177.8	-154.8	35.2	0	0	0	110.5	K46 I47 V49	K46-D274 HydrophobicContact CB-CB 4.37Å; K46-D274 HydrophobicContact CD-CB 4.2Å; K46-D274 IonicContact NZ-OD1 2.67Å; K46-D274 PolarHBondContact NZ-OD1 3.39Å; I47-D274 PolarHBondContact O-N 3.11Å; I47-D274 VanDerWaalsContact O-N 3.09Å; V49-D274 WeakPolarHBondContact CG2-O 3.15Å
275	I	84.1	Confident	88.5	Confident	9 Å²	9	43.2 Å²	43.2	5%	0.046	21%	0.207	C	C	.	.			trans	-123.8	126.1	-177.3	-58.8	157.7	0	0	0	107.3	F67 V121 R273 R277 L282 V283 A286 Y290	F67-I275 HydrophobicContact CE1-CD1 4.29Å; F67-I275 HydrophobicContact CE1-CG1 4.5Å; V121-I275 HydrophobicContact CG1-CD1 4.08Å; R273-I275 PolarHBondContact O-N 3.2Å; I275-R277 PolarHBondContact O-N 3.1Å; I275-R277 PolarHBondContact O-NH1 3.11Å; I275-R277 VanDerWaalsContact O-NH1 3.16Å; I275-L282 HydrophobicContact CG2-CB 4.2Å; I275-V283 HydrophobicContact CG2-CG2 4.4Å; I275-A286 HydrophobicContact CD1-CB 3.44Å; I275-A286 VanDerWaalsContact CD1-CB 3.44Å; I275-A286 HydrophobicContact CG1-CB 4.14Å; I275-A286 HydrophobicContact CG2-CB 4.48Å; I275-Y290 HydrophobicContact CD1-CE2 4.19Å
276	D	85.3	Confident	88.3	Confident	79 Å²	79	43.2 Å²	43.2	42%	0.422	21%	0.207	S	C	.	.			trans	-71.6	111.1	170.5	179.5	18.1	0	0	0	109.8	N278 N279 L282	D276-N278 VanDerWaalsContact C-N 3.29Å; D276-N278 WeakPolarHBondContact OD1-CB 3.41Å; D276-N278 PolarHBondContact OD1-N 3.28Å; D276-N278 PolarHBondContact OD1-ND2 2.78Å; D276-N279 PolarHBondContact O-N 3.36Å; D276-L282 HydrophobicContact CB-CD1 4.04Å
277	R	85.9	Confident	88.1	Confident	87 Å²	87	44.1 Å²	44.1	33%	0.328	21%	0.212	S	C	.	.	T	Hydrogen-bonded Turn	trans	-81.5	-10.9	-176	-65.8	169.4	-168.9	79.9	-0.6	112.8	V121 I275	V121-R277 PolarHBondContact O-NE 3.28Å; I275-R277 PolarHBondContact O-N 3.1Å; I275-R277 PolarHBondContact O-NH1 3.11Å; I275-R277 VanDerWaalsContact O-NH1 3.16Å
278	N	86.2	Confident	87.9	Confident	148 Å²	148	48 Å²	48	79%	0.791	23%	0.232	S	C	*	.	T	Hydrogen-bonded Turn	trans	-74.4	-21.6	173.7	-56	-58.9	0	0	0	111.4	D276 P280	D276-N278 VanDerWaalsContact C-N 3.29Å; D276-N278 WeakPolarHBondContact OD1-CB 3.41Å; D276-N278 PolarHBondContact OD1-N 3.28Å; D276-N278 PolarHBondContact OD1-ND2 2.78Å; N278-P280 WeakPolarHBondContact O-CD 3.32Å
279	N	86.6	Confident	87.9	Confident	48 Å²	48	48 Å²	48	26%	0.257	23%	0.23	S	C	.	.			trans	-99.9	105.4	177.7	-170.1	-14.2	0	0	0	111	D276 F281 L282 V283	D276-N279 PolarHBondContact O-N 3.36Å; N279-F281 PolarHBondContact O-N 3.42Å; N279-F281 VanDerWaalsContact O-N 3.16Å; N279-F281 WeakPolarHBondContact OD1-CB 3.36Å; N279-F281 PolarHBondContact OD1-N 3.39Å; N279-F281 VanDerWaalsContact OD1-N 3.12Å; N279-L282 HydrophobicContact CB-CB 4.41Å; N279-L282 HydrophobicContact CB-CD1 4.03Å; N279-L282 HydrophobicContact CB-CG 4.1Å; N279-L282 PolarHBondContact O-N 2.93Å; N279-L282 VanDerWaalsContact O-N 3.16Å; N279-V283 PolarHBondContact O-N 3.3Å
280	P	86.7	Confident	88	Confident	59 Å²	59	47.8 Å²	47.8	38%	0.383	23%	0.229	S	C	.	.	H	α-helix	trans	-63.3	-24.4	-178.1	26.2	-35.3	0	0	0	113.4	N278 V283 R284 E465 F466	N278-P280 WeakPolarHBondContact O-CD 3.32Å; P280-V283 PolarHBondContact O-N 2.78Å; P280-R284 WeakPolarHBondContact O-CB 3.43Å; P280-R284 PolarHBondContact O-N 3.12Å; P280-E465 WeakPolarHBondContact CB-OE1 3.39Å; P280-F466 HydrophobicContact CB-CE2 4.3Å; P280-F466 HydrophobicContact CB-CZ 3.93Å; P280-F466 WeakPolarHBondContact O-CZ 3.21Å
281	F	86.6	Confident	88.1	Confident	113 Å²	113	51 Å²	51	50%	0.496	24%	0.243	S	C	.	.	H	α-helix	trans	-63.5	-46.9	175.4	-179.8	-93.7	0	0	0	111.5	N279 V283 R284 E285	N279-F281 PolarHBondContact O-N 3.42Å; N279-F281 VanDerWaalsContact O-N 3.16Å; N279-F281 WeakPolarHBondContact OD1-CB 3.36Å; N279-F281 PolarHBondContact OD1-N 3.39Å; N279-F281 VanDerWaalsContact OD1-N 3.12Å; F281-V283 VanDerWaalsContact C-N 3.33Å; F281-V283 PolarHBondContact O-N 3.02Å; F281-R284 PolarHBondContact O-N 3.24Å; F281-E285 WeakPolarHBondContact O-CB 3.46Å; F281-E285 PolarHBondContact O-N 2.9Å
282	L	87.1	Confident	88.3	Confident	23 Å²	23	51.6 Å²	51.6	12%	0.12	25%	0.248	C	C	.	.	H	α-helix	trans	-65.8	-37.9	179.6	-64.2	-179.9	0	0	0	111.7	V51 I275 D276 N279 E285 A286	V51-L282 HydrophobicContact CB-CD2 4.31Å; V51-L282 HydrophobicContact CG1-CD2 3.89Å; V51-L282 HydrophobicContact CG2-CD2 4.06Å; I275-L282 HydrophobicContact CG2-CB 4.2Å; D276-L282 HydrophobicContact CB-CD1 4.04Å; N279-L282 HydrophobicContact CB-CB 4.41Å; N279-L282 HydrophobicContact CB-CD1 4.03Å; N279-L282 HydrophobicContact CB-CG 4.1Å; N279-L282 PolarHBondContact O-N 2.93Å; N279-L282 VanDerWaalsContact O-N 3.16Å; L282-E285 PolarHBondContact O-N 3.49Å; L282-A286 WeakPolarHBondContact O-CB 3.38Å; L282-A286 PolarHBondContact O-N 3.05Å
283	V	89.7	Confident	88.7	Confident	3 Å²	3	51.4 Å²	51.4	2%	0.018	25%	0.246	C	C	.	.	H	α-helix	trans	-63.6	-41.6	174.4	174.8	0	0	0	0	111.2	V121 V122 I275 N279 P280 F281 N287 F466	V121-V283 HydrophobicContact CG1-CG1 4.23Å; V122-V283 HydrophobicContact CG2-CG1 3.75Å; I275-V283 HydrophobicContact CG2-CG2 4.4Å; N279-V283 PolarHBondContact O-N 3.3Å; P280-V283 PolarHBondContact O-N 2.78Å; F281-V283 VanDerWaalsContact C-N 3.33Å; F281-V283 PolarHBondContact O-N 3.02Å; V283-N287 WeakPolarHBondContact O-CB 3.5Å; V283-N287 VanDerWaalsContact O-CG 3.24Å; V283-N287 PolarHBondContact O-N 3.24Å; V283-N287 PolarHBondContact O-ND2 3.19Å; V283-F466 HydrophobicContact CB-CE2 4.07Å; V283-F466 HydrophobicContact CB-CZ 3.87Å; V283-F466 HydrophobicContact CG1-CD1 4.45Å; V283-F466 HydrophobicContact CG1-CD2 4.01Å; V283-F466 HydrophobicContact CG1-CE1 4.07Å; V283-F466 HydrophobicContact CG1-CE2 3.6Å; V283-F466 HydrophobicContact CG1-CG 4.43Å; V283-F466 HydrophobicContact CG1-CZ 3.63Å
284	R	88.8	Confident	89.2	Confident	186 Å²	186	51.5 Å²	51.5	70%	0.702	25%	0.246	S	C	*	.	H	α-helix	trans	-67.1	-42.5	176.9	-170.5	174.5	-173.1	160	0.3	111.9	P280 F281 N287 M288 F466	P280-R284 WeakPolarHBondContact O-CB 3.43Å; P280-R284 PolarHBondContact O-N 3.12Å; F281-R284 PolarHBondContact O-N 3.24Å; R284-N287 PolarHBondContact O-N 3.48Å; R284-M288 PolarHBondContact O-N 3.24Å; R284-F466 HydrophobicContact CB-CE1 4.23Å
285	E	88.8	Confident	89.8	Confident	24 Å²	24	50.1 Å²	50.1	11%	0.112	24%	0.241	C	C	.	.	H	α-helix	trans	-63.1	-48.5	177.1	-178	174	-159.1	0	0	111.3	R63 F281 L282 N287 M288 Y289	R63-E285 WeakPolarHBondContact CD-OE1 3.44Å; R63-E285 IonicContact CZ-OE1 4Å; R63-E285 IonicContact NE-OE1 3.27Å; R63-E285 IonicContact NH1-OE1 3.74Å; R63-E285 PolarHBondContact NH1-OE1 3.2Å; R63-E285 IonicContact NH1-OE2 2.73Å; F281-E285 WeakPolarHBondContact O-CB 3.46Å; F281-E285 PolarHBondContact O-N 2.9Å; L282-E285 PolarHBondContact O-N 3.49Å; E285-N287 VanDerWaalsContact C-N 3.34Å; E285-N287 PolarHBondContact O-N 2.62Å; E285-M288 WeakPolarHBondContact O-CB 3.45Å; E285-M288 PolarHBondContact O-N 2.97Å; E285-Y289 HydrophobicContact CG-CD2 3.73Å; E285-Y289 HydrophobicContact CG-CE2 3.35Å; E285-Y289 VanDerWaalsContact O-CD2 3.32Å; E285-Y289 WeakPolarHBondContact O-CD2 3.42Å; E285-Y289 PolarHBondContact O-N 2.79Å; E285-Y289 WeakPolarHBondContact OE1-CE2 3.42Å
286	A	91	Very high	90.3	Very high	1 Å²	1	53.4 Å²	53.4	1%	0.008	26%	0.258	C	S	.	.	H	α-helix	trans	-59.3	-44.3	176.2	0	0	0	0	0	112	F67 V121 I275 L282 M288 Y289 Y290	F67-A286 HydrophobicContact CE1-CB 3.95Å; F67-A286 HydrophobicContact CZ-CB 4.19Å; V121-A286 HydrophobicContact CG1-CB 4.02Å; I275-A286 HydrophobicContact CD1-CB 3.44Å; I275-A286 VanDerWaalsContact CD1-CB 3.44Å; I275-A286 HydrophobicContact CG1-CB 4.14Å; I275-A286 HydrophobicContact CG2-CB 4.48Å; L282-A286 WeakPolarHBondContact O-CB 3.38Å; L282-A286 PolarHBondContact O-N 3.05Å; A286-M288 PolarHBondContact O-N 3.24Å; A286-Y289 PolarHBondContact O-N 3.11Å; A286-Y290 HydrophobicContact CB-CD2 4.4Å; A286-Y290 HydrophobicContact CB-CE2 4.37Å; A286-Y290 WeakPolarHBondContact O-CB 3.33Å; A286-Y290 WeakPolarHBondContact O-CD2 3.45Å; A286-Y290 PolarHBondContact O-N 2.6Å
287	N	90.9	Very high	90.7	Very high	19 Å²	19	49.7 Å²	49.7	10%	0.102	24%	0.238	C	C	.	.	H	α-helix	trans	-60.9	-32.3	175.5	-78.8	-40.9	0	0	0	113	R118 V283 R284 E285 F291	R118-N287 WeakPolarHBondContact CG-OD1 3.38Å; V283-N287 WeakPolarHBondContact O-CB 3.5Å; V283-N287 VanDerWaalsContact O-CG 3.24Å; V283-N287 PolarHBondContact O-N 3.24Å; V283-N287 PolarHBondContact O-ND2 3.19Å; R284-N287 PolarHBondContact O-N 3.48Å; E285-N287 VanDerWaalsContact C-N 3.34Å; E285-N287 PolarHBondContact O-N 2.62Å; N287-F291 VanDerWaalsContact O-CB 3.27Å; N287-F291 WeakPolarHBondContact O-CB 3.27Å; N287-F291 PolarHBondContact O-N 3.31Å
288	M	90.6	Very high	91.1	Very high	83 Å²	83	45.7 Å²	45.7	41%	0.409	22%	0.223	S	C	.	.	H	α-helix	trans	-69.9	-49.8	174.9	-176.8	-171.5	72.3	0	0	111	R284 E285 A286 F291 I292	R284-M288 PolarHBondContact O-N 3.24Å; E285-M288 WeakPolarHBondContact O-CB 3.45Å; E285-M288 PolarHBondContact O-N 2.97Å; A286-M288 PolarHBondContact O-N 3.24Å; M288-F291 PolarHBondContact O-N 2.89Å; M288-I292 HydrophobicContact CG-CD1 4.05Å; M288-I292 WeakPolarHBondContact O-CG1 3.39Å; M288-I292 PolarHBondContact O-N 3.01Å
289	Y	92.6	Very high	91.5	Very high	3 Å²	3	44.5 Å²	44.5	1%	0.012	21%	0.211	C	C	.	.	H	α-helix	trans	-63.6	-44.4	180	-73.7	-63	0	0	0	112.4	F59 S60 R63 L64 F67 E285 A286 F291 I292 E293	F59-Y289 HydrophobicContact CD2-CD1 4.48Å; F59-Y289 AromaticContact CD2-CE1 3.76Å; F59-Y289 HydrophobicContact CD2-CE1 3.76Å; F59-Y289 HydrophobicContact CE2-CD1 4.25Å; F59-Y289 AromaticContact CE2-CE1 3.85Å; F59-Y289 HydrophobicContact CE2-CE1 3.85Å; S60-Y289 PolarHBondContact N-OH 3.45Å; R63-Y289 HydrophobicContact CB-CE1 4.14Å; R63-Y289 HydrophobicContact CB-CE2 3.86Å; L64-Y289 HydrophobicContact CB-CD1 3.94Å; L64-Y289 HydrophobicContact CB-CE1 4.11Å; L64-Y289 HydrophobicContact CD1-CD1 3.97Å; F67-Y289 AromaticContact CD2-CD2 3.74Å; F67-Y289 HydrophobicContact CD2-CD2 3.74Å; F67-Y289 AromaticContact CD2-CG 3.87Å; F67-Y289 HydrophobicContact CD2-CG 3.87Å; F67-Y289 AromaticContact CE2-CD2 3.79Å; F67-Y289 HydrophobicContact CE2-CD2 3.79Å; F67-Y289 HydrophobicContact CE2-CE2 4.42Å; F67-Y289 HydrophobicContact CE2-CG 4.39Å; F67-Y289 HydrophobicContact CG-CG 4.43Å; E285-Y289 HydrophobicContact CG-CD2 3.73Å; E285-Y289 HydrophobicContact CG-CE2 3.35Å; E285-Y289 VanDerWaalsContact O-CD2 3.32Å; E285-Y289 WeakPolarHBondContact O-CD2 3.42Å; E285-Y289 PolarHBondContact O-N 2.79Å; E285-Y289 WeakPolarHBondContact OE1-CE2 3.42Å; A286-Y289 PolarHBondContact O-N 3.11Å; Y289-F291 VanDerWaalsContact C-N 3.27Å; Y289-F291 PolarHBondContact O-N 3.13Å; Y289-I292 PolarHBondContact O-N 3.35Å; Y289-E293 WeakPolarHBondContact O-CB 3.22Å; Y289-E293 PolarHBondContact O-N 3.28Å
290	Y	93.2	Very high	91.9	Very high	2 Å²	2	44.3 Å²	44.3	1%	0.008	21%	0.212	C	C	.	.	H	α-helix	trans	-62.5	-34.4	175.5	-75.6	-51.7	0	0	0	112.9	F67 P70 V121 V270 R273 I275 A286 S294	F67-Y290 HydrophobicContact CB-CE1 4.45Å; F67-Y290 HydrophobicContact CD1-CD1 4.44Å; F67-Y290 HydrophobicContact CD1-CD2 4.43Å; F67-Y290 AromaticContact CD1-CE1 3.9Å; F67-Y290 HydrophobicContact CD1-CE1 3.9Å; F67-Y290 AromaticContact CD1-CE2 3.94Å; F67-Y290 HydrophobicContact CD1-CE2 3.94Å; F67-Y290 AromaticContact CD1-CZ 3.67Å; F67-Y290 HydrophobicContact CE1-CE2 4.16Å; P70-Y290 HydrophobicContact CB-CE1 4.39Å; P70-Y290 HydrophobicContact CG-CE1 3.87Å; V121-Y290 HydrophobicContact CG2-CD2 3.52Å; V121-Y290 HydrophobicContact CG2-CE2 3.51Å; V270-Y290 HydrophobicContact CB-CD2 4.36Å; V270-Y290 HydrophobicContact CB-CE1 4.29Å; V270-Y290 HydrophobicContact CB-CE2 3.86Å; V270-Y290 HydrophobicContact CG1-CD1 3.99Å; V270-Y290 HydrophobicContact CG1-CD2 4.15Å; V270-Y290 HydrophobicContact CG1-CE1 3.96Å; V270-Y290 HydrophobicContact CG1-CE2 4.08Å; V270-Y290 HydrophobicContact CG1-CG 4.09Å; V270-Y290 PolarHBondContact O-OH 3.46Å; R273-Y290 VanDerWaalsContact CB-OH 3.29Å; R273-Y290 WeakPolarHBondContact CB-OH 3.17Å; R273-Y290 VanDerWaalsContact CD-OH 3.3Å; R273-Y290 WeakPolarHBondContact CD-OH 3.32Å; R273-Y290 WeakPolarHBondContact CG-OH 3.4Å; I275-Y290 HydrophobicContact CD1-CE2 4.19Å; A286-Y290 HydrophobicContact CB-CD2 4.4Å; A286-Y290 HydrophobicContact CB-CE2 4.37Å; A286-Y290 WeakPolarHBondContact O-CB 3.33Å; A286-Y290 WeakPolarHBondContact O-CD2 3.45Å; A286-Y290 PolarHBondContact O-N 2.6Å; Y290-S294 VanDerWaalsContact O-CB 3.26Å; Y290-S294 WeakPolarHBondContact O-CB 3.44Å; Y290-S294 PolarHBondContact O-N 3.27Å; Y290-S294 PolarHBondContact O-OG 3.03Å
291	F	93.7	Very high	92.2	Very high	69 Å²	69	41.6 Å²	41.6	30%	0.303	19%	0.194	S	C	.	.	H	α-helix	trans	-67.7	-45.4	175.1	177.2	-112.5	0	0	0	111.9	L110 R114 N287 M288 Y289 T295	L110-F291 HydrophobicContact CD1-CE2 4.37Å; L110-F291 HydrophobicContact CG-CE2 4.41Å; R114-F291 HydrophobicContact CB-CD2 4.17Å; R114-F291 HydrophobicContact CG-CD2 3.82Å; R114-F291 HydrophobicContact CG-CE2 4.42Å; N287-F291 VanDerWaalsContact O-CB 3.27Å; N287-F291 WeakPolarHBondContact O-CB 3.27Å; N287-F291 PolarHBondContact O-N 3.31Å; M288-F291 PolarHBondContact O-N 2.89Å; Y289-F291 VanDerWaalsContact C-N 3.27Å; Y289-F291 PolarHBondContact O-N 3.13Å; F291-T295 WeakPolarHBondContact O-CB 3.45Å; F291-T295 PolarHBondContact O-N 3.39Å; F291-T295 PolarHBondContact O-OG1 2.78Å
292	I	93.9	Very high	92.7	Very high	47 Å²	47	36.9 Å²	36.9	24%	0.241	17%	0.174	C	C	.	.	H	α-helix	trans	-60.7	-49.2	177	-68	169	0	0	0	110	F59 L64 M288 Y289 T295 I296	F59-I292 HydrophobicContact CD2-CD1 4.12Å; F59-I292 HydrophobicContact CE2-CD1 3.73Å; L64-I292 HydrophobicContact CD1-CB 4.37Å; L64-I292 HydrophobicContact CD1-CG2 4.03Å; L64-I292 HydrophobicContact CD2-CG2 4.27Å; M288-I292 HydrophobicContact CG-CD1 4.05Å; M288-I292 WeakPolarHBondContact O-CG1 3.39Å; M288-I292 PolarHBondContact O-N 3.01Å; Y289-I292 PolarHBondContact O-N 3.35Å; I292-T295 WeakPolarHBondContact O-CB 3.4Å; I292-T295 PolarHBondContact O-N 2.65Å; I292-I296 HydrophobicContact CG2-CD1 3.86Å; I292-I296 WeakPolarHBondContact O-CG1 3.28Å; I292-I296 PolarHBondContact O-N 2.89Å
293	E	93.6	Very high	93	Very high	2 Å²	2	38.4 Å²	38.4	1%	0.009	18%	0.181	C	C	.	.	H	α-helix	trans	-58.3	-51.4	178.9	-173.8	-149.5	165.8	0	0	112	L64 T68 G69 P70 G71 Y289 T295 I296 A297	L64-E293 HydrophobicContact CD1-CB 4.42Å; T68-E293 HydrophobicContact CG2-CG 4.45Å; G69-E293 VanDerWaalsContact C-OE1 3.25Å; G69-E293 WeakPolarHBondContact CA-OE1 3.35Å; G69-E293 PolarHBondContact N-OE1 2.99Å; P70-E293 WeakPolarHBondContact CD-OE1 3.16Å; G71-E293 WeakPolarHBondContact CA-OE1 3.44Å; G71-E293 PolarHBondContact N-OE1 3.45Å; Y289-E293 WeakPolarHBondContact O-CB 3.22Å; Y289-E293 PolarHBondContact O-N 3.28Å; E293-T295 PolarHBondContact O-N 2.9Å; E293-I296 PolarHBondContact O-N 3.31Å; E293-A297 PolarHBondContact O-N 3.29Å
294	S	94.4	Very high	93.2	Very high	1 Å²	1	38.3 Å²	38.3	1%	0.007	18%	0.18	C	C	.	.	H	α-helix	trans	-61.9	-34.9	178.9	-59.1	0	0	0	0	112.1	H266 Y290 L298	H266-S294 PolarHBondContact CE1-OG 2.92Å; H266-S294 PolarHBondContact NE2-OG 2.78Å; Y290-S294 VanDerWaalsContact O-CB 3.26Å; Y290-S294 WeakPolarHBondContact O-CB 3.44Å; Y290-S294 PolarHBondContact O-N 3.27Å; Y290-S294 PolarHBondContact O-OG 3.03Å; S294-L298 WeakPolarHBondContact O-CB 3.37Å; S294-L298 WeakPolarHBondContact O-CG 3.49Å; S294-L298 PolarHBondContact O-N 2.56Å
295	T	95.8	Very high	93.5	Very high	47 Å²	47	29.5 Å²	29.5	29%	0.288	15%	0.147	S	C	.	.	H	α-helix	trans	-66	-44.4	176.2	-57.9	0	0	0	0	110.8	L110 F291 I292 E293 F299	L110-T295 HydrophobicContact CD2-CG2 4.14Å; F291-T295 WeakPolarHBondContact O-CB 3.45Å; F291-T295 PolarHBondContact O-N 3.39Å; F291-T295 PolarHBondContact O-OG1 2.78Å; I292-T295 WeakPolarHBondContact O-CB 3.4Å; I292-T295 PolarHBondContact O-N 2.65Å; E293-T295 PolarHBondContact O-N 2.9Å; T295-F299 WeakPolarHBondContact O-CB 3.36Å; T295-F299 PolarHBondContact O-N 3.47Å
296	I	94.6	Very high	93.8	Very high	78 Å²	78	28.8 Å²	28.8	40%	0.4	14%	0.144	S	C	.	.	H	α-helix	trans	-62.7	-47.4	176.6	-66.5	165.8	0	0	0	110.2	I292 E293 F299 V300	I292-I296 HydrophobicContact CG2-CD1 3.86Å; I292-I296 WeakPolarHBondContact O-CG1 3.28Å; I292-I296 PolarHBondContact O-N 2.89Å; E293-I296 PolarHBondContact O-N 3.31Å; I296-F299 PolarHBondContact O-N 3.36Å; I296-V300 WeakPolarHBondContact O-CG2 3.31Å; I296-V300 PolarHBondContact O-N 3.09Å
297	A	93.6	Very high	94	Very high	0 Å²	0	30.8 Å²	30.8	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-63.5	-45	-178	0	0	0	0	0	112.6	G71 F72 E293 V300 S301	G71-A297 WeakPolarHBondContact O-CB 3.41Å; F72-A297 HydrophobicContact CD1-CB 4.24Å; F72-A297 HydrophobicContact CD2-CB 4.43Å; F72-A297 HydrophobicContact CE1-CB 4.44Å; F72-A297 HydrophobicContact CG-CB 4.25Å; E293-A297 PolarHBondContact O-N 3.29Å; A297-V300 PolarHBondContact O-N 3.24Å; A297-S301 PolarHBondContact O-N 3.35Å; A297-S301 PolarHBondContact O-OG 3.33Å
298	L	94.7	Very high	94.1	Very high	3 Å²	3	29.9 Å²	29.9	2%	0.016	15%	0.148	C	C	.	.	H	α-helix	trans	-72.1	-28.5	176.1	-68.8	-177.2	0	0	0	113.1	M74 Y78 T106 L110 S294 S301 L302	M74-L298 HydrophobicContact CE-CD1 3.95Å; M74-L298 HydrophobicContact CE-CD2 4.1Å; M74-L298 HydrophobicContact CE-CG 3.9Å; M74-L298 HydrophobicContact SD-CD1 4.4Å; M74-L298 HydrophobicContact SD-CD2 3.94Å; M74-L298 HydrophobicContact SD-CG 4.37Å; Y78-L298 HydrophobicContact CD1-CD2 3.85Å; Y78-L298 HydrophobicContact CD2-CD2 3.37Å; Y78-L298 HydrophobicContact CE1-CD2 3.9Å; Y78-L298 HydrophobicContact CE2-CD2 3.44Å; Y78-L298 VanDerWaalsContact CE2-CD2 3.44Å; Y78-L298 HydrophobicContact CG-CD2 3.6Å; T106-L298 HydrophobicContact CG2-CB 4.44Å; L110-L298 VanDerWaalsContact CA-CD1 3.49Å; L110-L298 HydrophobicContact CB-CD1 3.64Å; L110-L298 HydrophobicContact CD1-CD1 3.87Å; L110-L298 HydrophobicContact CG-CD1 4.35Å; S294-L298 WeakPolarHBondContact O-CB 3.37Å; S294-L298 WeakPolarHBondContact O-CG 3.49Å; S294-L298 PolarHBondContact O-N 2.56Å; L298-S301 PolarHBondContact O-N 3.12Å; L298-L302 WeakPolarHBondContact O-CB 3.17Å; L298-L302 PolarHBondContact O-N 3.33Å
299	F	95.6	Very high	94.3	Very high	123 Å²	123	26 Å²	26	54%	0.539	13%	0.129	S	C	.	.	H	α-helix	trans	-66.2	-44.5	172	178.6	-100.5	0	0	0	111.5	T295 I296 S301 L302 M303	T295-F299 WeakPolarHBondContact O-CB 3.36Å; T295-F299 PolarHBondContact O-N 3.47Å; I296-F299 PolarHBondContact O-N 3.36Å; F299-S301 VanDerWaalsContact C-N 3.29Å; F299-S301 PolarHBondContact O-N 2.91Å; F299-L302 PolarHBondContact O-N 2.92Å; F299-M303 HydrophobicContact CD1-CG 4.44Å; F299-M303 HydrophobicContact CD2-CE 4.43Å; F299-M303 HydrophobicContact CE1-CG 4.03Å; F299-M303 HydrophobicContact CE2-CE 3.84Å; F299-M303 HydrophobicContact CE2-SD 4.43Å; F299-M303 HydrophobicContact CZ-CE 4.08Å; F299-M303 HydrophobicContact CZ-CG 4.09Å; F299-M303 HydrophobicContact CZ-SD 4.05Å; F299-M303 WeakPolarHBondContact O-CG 3.06Å; F299-M303 PolarHBondContact O-N 3.15Å
300	V	93.8	Very high	94.4	Very high	45 Å²	45	25.9 Å²	25.9	27%	0.273	13%	0.129	S	C	.	.	H	α-helix	trans	-59.8	-43	173.6	172.8	0	0	0	0	110.6	I209 I296 A297 M303 I304	I209-V300 HydrophobicContact CG2-CG1 3.79Å; I296-V300 WeakPolarHBondContact O-CG2 3.31Å; I296-V300 PolarHBondContact O-N 3.09Å; A297-V300 PolarHBondContact O-N 3.24Å; V300-M303 PolarHBondContact O-N 3.01Å; V300-I304 HydrophobicContact CG1-CD1 4.3Å; V300-I304 PolarHBondContact O-N 3.41Å; V300-I304 VanDerWaalsContact O-N 3.15Å
301	S	94.2	Very high	94.3	Very high	1 Å²	1	25.8 Å²	25.8	1%	0.007	13%	0.128	C	C	.	.	H	α-helix	trans	-63.1	-46.5	177.7	-52.2	0	0	0	0	111.4	S75 A297 L298 F299 M303 I304 N305	S75-S301 WeakPolarHBondContact CB-OG 3.29Å; A297-S301 PolarHBondContact O-N 3.35Å; A297-S301 PolarHBondContact O-OG 3.33Å; L298-S301 PolarHBondContact O-N 3.12Å; F299-S301 VanDerWaalsContact C-N 3.29Å; F299-S301 PolarHBondContact O-N 2.91Å; S301-M303 VanDerWaalsContact C-N 3.27Å; S301-M303 PolarHBondContact O-N 3.27Å; S301-I304 WeakPolarHBondContact O-CB 3.15Å; S301-I304 PolarHBondContact O-N 2.97Å; S301-I304 VanDerWaalsContact O-N 3.09Å; S301-N305 PolarHBondContact O-N 3.16Å; S301-N305 PolarHBondContact O-OD1 2.96Å
302	L	95.3	Very high	94.3	Very high	14 Å²	14	22.5 Å²	22.5	7%	0.073	11%	0.114	C	C	.	.	H	α-helix	trans	-55.9	-40.5	174.7	179.6	65	0	0	0	112.6	L102 L103 T106 L298 F299 N305 I306	L102-L302 HydrophobicContact CG-CD1 4.38Å; L103-L302 HydrophobicContact CD1-CD1 4.42Å; L103-L302 HydrophobicContact CD1-CD2 3.58Å; T106-L302 HydrophobicContact CG2-CB 4.2Å; T106-L302 HydrophobicContact CG2-CD1 4.38Å; L298-L302 WeakPolarHBondContact O-CB 3.17Å; L298-L302 PolarHBondContact O-N 3.33Å; F299-L302 PolarHBondContact O-N 2.92Å; L302-N305 PolarHBondContact O-N 2.92Å; L302-I306 HydrophobicContact CD1-CD1 4.17Å; L302-I306 HydrophobicContact CD1-CG1 4.35Å; L302-I306 HydrophobicContact CG-CD1 3.97Å; L302-I306 WeakPolarHBondContact O-CB 2.93Å; L302-I306 VanDerWaalsContact O-CG1 3.27Å; L302-I306 WeakPolarHBondContact O-CG1 2.95Å; L302-I306 PolarHBondContact O-N 3.29Å
303	M	94.9	Very high	94.2	Very high	56 Å²	56	20.4 Å²	20.4	28%	0.276	10%	0.103	S	C	.	.	H	α-helix	trans	-63.5	-43.6	177.2	-69.3	-60.1	99.3	0	0	111.5	F299 V300 S301 I306 F307	F299-M303 HydrophobicContact CD1-CG 4.44Å; F299-M303 HydrophobicContact CD2-CE 4.43Å; F299-M303 HydrophobicContact CE1-CG 4.03Å; F299-M303 HydrophobicContact CE2-CE 3.84Å; F299-M303 HydrophobicContact CE2-SD 4.43Å; F299-M303 HydrophobicContact CZ-CE 4.08Å; F299-M303 HydrophobicContact CZ-CG 4.09Å; F299-M303 HydrophobicContact CZ-SD 4.05Å; F299-M303 WeakPolarHBondContact O-CG 3.06Å; F299-M303 PolarHBondContact O-N 3.15Å; V300-M303 PolarHBondContact O-N 3.01Å; S301-M303 VanDerWaalsContact C-N 3.27Å; S301-M303 PolarHBondContact O-N 3.27Å; M303-I306 HydrophobicContact CE-CD1 3.74Å; M303-I306 PolarHBondContact O-N 3.33Å; M303-F307 WeakPolarHBondContact O-CD2 3.39Å; M303-F307 WeakPolarHBondContact O-CG 3.49Å; M303-F307 PolarHBondContact O-N 2.99Å
304	I	93.6	Very high	94.1	Very high	1 Å²	1	22.1 Å²	22.1	1%	0.005	12%	0.118	C	C	.	.	H	α-helix	trans	-60.6	-48.1	175.3	-66.2	164.8	0	0	0	110.3	L79 I209 M212 A213 F216 V300 S301 I306 F307 V308	L79-I304 HydrophobicContact CD1-CD1 3.71Å; L79-I304 HydrophobicContact CD2-CB 3.77Å; L79-I304 HydrophobicContact CD2-CD1 3.86Å; L79-I304 HydrophobicContact CD2-CG1 4.43Å; L79-I304 HydrophobicContact CD2-CG2 3.67Å; L79-I304 HydrophobicContact CG-CD1 4.47Å; I209-I304 HydrophobicContact CG2-CD1 4.06Å; M212-I304 HydrophobicContact CB-CD1 4.29Å; A213-I304 HydrophobicContact CB-CD1 4.09Å; A213-I304 HydrophobicContact CB-CG1 4.07Å; F216-I304 HydrophobicContact CD2-CG2 3.74Å; F216-I304 HydrophobicContact CE2-CG2 4.3Å; V300-I304 HydrophobicContact CG1-CD1 4.3Å; V300-I304 PolarHBondContact O-N 3.41Å; V300-I304 VanDerWaalsContact O-N 3.15Å; S301-I304 WeakPolarHBondContact O-CB 3.15Å; S301-I304 PolarHBondContact O-N 2.97Å; S301-I304 VanDerWaalsContact O-N 3.09Å; I304-I306 VanDerWaalsContact C-N 3.33Å; I304-I306 PolarHBondContact O-N 2.96Å; I304-F307 WeakPolarHBondContact O-CA 3.21Å; I304-F307 WeakPolarHBondContact O-CB 3.5Å; I304-F307 PolarHBondContact O-N 3.4Å; I304-V308 HydrophobicContact CG2-CG2 4.36Å; I304-V308 WeakPolarHBondContact O-CG2 3.49Å; I304-V308 PolarHBondContact O-N 3.1Å
305	N	95	Very high	93.8	Very high	1 Å²	1	22.3 Å²	22.3	1%	0.005	12%	0.12	C	C	.	.	H	α-helix	trans	-59.4	-44.4	179.5	-67.3	32	0	0	0	111	Y78 L79 N83 D87 L102 S301 L302 F307 V308 V309	Y78-N305 PolarHBondContact O-ND2 2.92Å; Y78-N305 PolarHBondContact O-OD1 3.21Å; L79-N305 WeakPolarHBondContact CD2-OD1 3.48Å; N83-N305 PolarHBondContact ND2-ND2 3.3Å; N83-N305 VanDerWaalsContact ND2-ND2 3.14Å; D87-N305 WeakPolarHBondContact OD2-CA 3.47Å; D87-N305 WeakPolarHBondContact OD2-CB 3.43Å; D87-N305 PolarHBondContact OD2-ND2 2.86Å; L102-N305 HydrophobicContact CD1-CB 4.24Å; L102-N305 HydrophobicContact CD2-CB 3.81Å; L102-N305 HydrophobicContact CG-CB 4.49Å; S301-N305 PolarHBondContact O-N 3.16Å; S301-N305 PolarHBondContact O-OD1 2.96Å; L302-N305 PolarHBondContact O-N 2.92Å; N305-F307 VanDerWaalsContact C-N 3.32Å; N305-F307 PolarHBondContact O-N 3.29Å; N305-V308 PolarHBondContact O-N 3.49Å; N305-V309 VanDerWaalsContact O-CG2 3.28Å; N305-V309 WeakPolarHBondContact O-CG2 3.29Å; N305-V309 PolarHBondContact O-N 3.2Å
306	I	95.2	Very high	93.5	Very high	9 Å²	9	20.2 Å²	20.2	5%	0.046	11%	0.107	C	C	.	.	H	α-helix	trans	-59.7	-42.1	174.2	-70.1	169.1	0	0	0	111.2	L99 L230 L234 L302 M303 I304 S310	L99-I306 HydrophobicContact CD2-CG1 4.37Å; L230-I306 HydrophobicContact CD1-CG2 4.35Å; L230-I306 HydrophobicContact CD2-CG2 4.24Å; L234-I306 HydrophobicContact CD1-CD1 3.94Å; L234-I306 HydrophobicContact CD1-CG1 4.46Å; L234-I306 HydrophobicContact CD2-CD1 4.27Å; L302-I306 HydrophobicContact CD1-CD1 4.17Å; L302-I306 HydrophobicContact CD1-CG1 4.35Å; L302-I306 HydrophobicContact CG-CD1 3.97Å; L302-I306 WeakPolarHBondContact O-CB 2.93Å; L302-I306 VanDerWaalsContact O-CG1 3.27Å; L302-I306 WeakPolarHBondContact O-CG1 2.95Å; L302-I306 PolarHBondContact O-N 3.29Å; M303-I306 HydrophobicContact CE-CD1 3.74Å; M303-I306 PolarHBondContact O-N 3.33Å; I304-I306 VanDerWaalsContact C-N 3.33Å; I304-I306 PolarHBondContact O-N 2.96Å; I306-S310 WeakPolarHBondContact O-CB 3.3Å; I306-S310 PolarHBondContact O-N 3.41Å; I306-S310 PolarHBondContact O-OG 3.08Å
307	F	94.1	Very high	93.2	Very high	42 Å²	42	20.1 Å²	20.1	18%	0.184	10%	0.102	C	C	.	.	H	α-helix	trans	-60.9	-47.6	176.2	-62.4	-26.1	0	0	0	111.6	F216 Y220 M303 I304 N305 S310 V311	F216-F307 HydrophobicContact CB-CB 3.93Å; F216-F307 HydrophobicContact CB-CD2 4.18Å; Y220-F307 AromaticContact CD1-CD1 3.93Å; Y220-F307 HydrophobicContact CD1-CD1 3.93Å; Y220-F307 AromaticContact CD1-CE1 3.89Å; Y220-F307 HydrophobicContact CD1-CE1 3.89Å; Y220-F307 HydrophobicContact CD2-CB 4.49Å; Y220-F307 AromaticContact CD2-CD1 3.63Å; Y220-F307 HydrophobicContact CD2-CD1 3.63Å; Y220-F307 HydrophobicContact CD2-CE1 4.36Å; Y220-F307 HydrophobicContact CD2-CG 4.45Å; Y220-F307 HydrophobicContact CE1-CD1 4.46Å; Y220-F307 HydrophobicContact CE1-CE1 4.26Å; Y220-F307 HydrophobicContact CE2-CD1 4.16Å; Y220-F307 AromaticContact CG-CD1 3.48Å; Y220-F307 HydrophobicContact CG-CD1 3.48Å; Y220-F307 VanDerWaalsContact CG-CD1 3.48Å; Y220-F307 AromaticContact CG-CE1 3.94Å; Y220-F307 HydrophobicContact CG-CE1 3.94Å; Y220-F307 HydrophobicContact CG-CG 4.27Å; M303-F307 WeakPolarHBondContact O-CD2 3.39Å; M303-F307 WeakPolarHBondContact O-CG 3.49Å; M303-F307 PolarHBondContact O-N 2.99Å; I304-F307 WeakPolarHBondContact O-CA 3.21Å; I304-F307 WeakPolarHBondContact O-CB 3.5Å; I304-F307 PolarHBondContact O-N 3.4Å; N305-F307 VanDerWaalsContact C-N 3.32Å; N305-F307 PolarHBondContact O-N 3.29Å; F307-S310 PolarHBondContact O-N 2.92Å; F307-V311 WeakPolarHBondContact O-CB 3.43Å; F307-V311 VanDerWaalsContact O-CG2 3.26Å; F307-V311 WeakPolarHBondContact O-CG2 3.42Å; F307-V311 PolarHBondContact O-N 2.94Å
308	V	93.5	Very high	92.8	Very high	1 Å²	1	23.8 Å²	23.8	1%	0.006	14%	0.14	C	C	.	.	H	α-helix	trans	-59.2	-54.9	178.6	173.1	0	0	0	0	110.9	I84 D87 L88 F216 I304 N305 S310 V311 F312	I84-V308 HydrophobicContact CG2-CG1 4.4Å; D87-V308 HydrophobicContact CB-CB 4.26Å; D87-V308 HydrophobicContact CB-CG1 3.77Å; L88-V308 HydrophobicContact CB-CG1 4.19Å; F216-V308 HydrophobicContact CD1-CG2 4.22Å; F216-V308 HydrophobicContact CD2-CG2 4.13Å; F216-V308 HydrophobicContact CE1-CG2 4.3Å; F216-V308 HydrophobicContact CE2-CG2 4.19Å; F216-V308 HydrophobicContact CG-CG2 4.15Å; F216-V308 HydrophobicContact CZ-CG2 4.29Å; I304-V308 HydrophobicContact CG2-CG2 4.36Å; I304-V308 WeakPolarHBondContact O-CG2 3.49Å; I304-V308 PolarHBondContact O-N 3.1Å; N305-V308 PolarHBondContact O-N 3.49Å; V308-S310 PolarHBondContact O-N 3.18Å; V308-V311 PolarHBondContact O-N 2.86Å; V308-F312 HydrophobicContact CG1-CD2 3.79Å; V308-F312 HydrophobicContact CG1-CE2 3.96Å; V308-F312 WeakPolarHBondContact O-CD2 3.2Å; V308-F312 PolarHBondContact O-N 2.88Å; V308-F312 VanDerWaalsContact O-N 3.12Å
309	V	94.9	Very high	92.5	Very high	2 Å²	2	28.4 Å²	28.4	1%	0.012	16%	0.16	C	C	.	.	H	α-helix	trans	-54.2	-41.3	177.4	177.6	0	0	0	0	110.7	D87 S90 G91 L99 L102 N305 G313	D87-V309 HydrophobicContact CB-CG2 3.71Å; D87-V309 WeakPolarHBondContact O-CG2 3.34Å; S90-V309 WeakPolarHBondContact OG-CG2 3.36Å; G91-V309 WeakPolarHBondContact CA-O 3.3Å; L99-V309 HydrophobicContact CD2-CB 3.87Å; L99-V309 HydrophobicContact CD2-CG1 3.6Å; L99-V309 HydrophobicContact CD2-CG2 4.19Å; L99-V309 HydrophobicContact CG-CG1 4.15Å; L102-V309 HydrophobicContact CD2-CG2 3.95Å; N305-V309 VanDerWaalsContact O-CG2 3.28Å; N305-V309 WeakPolarHBondContact O-CG2 3.29Å; N305-V309 PolarHBondContact O-N 3.2Å; V309-G313 WeakPolarHBondContact O-CA 3.34Å; V309-G313 PolarHBondContact O-N 3.23Å
310	S	94.1	Very high	91.9	Very high	0 Å²	0	25.9 Å²	25.9	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-73.3	-42	-173.5	-57.1	0	0	0	0	113.5	L230 I306 F307 V308 A314	L230-S310 WeakPolarHBondContact CD1-OG 3.38Å; I306-S310 WeakPolarHBondContact O-CB 3.3Å; I306-S310 PolarHBondContact O-N 3.41Å; I306-S310 PolarHBondContact O-OG 3.08Å; F307-S310 PolarHBondContact O-N 2.92Å; V308-S310 PolarHBondContact O-N 3.18Å; S310-A314 WeakPolarHBondContact O-CB 3.46Å; S310-A314 PolarHBondContact O-N 2.81Å; S310-A314 VanDerWaalsContact O-N 3.07Å
311	V	92.3	Very high	91.4	Very high	0 Å²	0	23.9 Å²	23.9	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-64.1	-48.1	178.2	168.7	0	0	0	0	110.1	E219 V223 F307 V308 G315 F358 L359	E219-V311 HydrophobicContact CB-CG2 4.04Å; V223-V311 HydrophobicContact CG2-CB 4.46Å; V223-V311 HydrophobicContact CG2-CG1 4.11Å; V223-V311 HydrophobicContact CG2-CG2 4.14Å; F307-V311 WeakPolarHBondContact O-CB 3.43Å; F307-V311 VanDerWaalsContact O-CG2 3.26Å; F307-V311 WeakPolarHBondContact O-CG2 3.42Å; F307-V311 PolarHBondContact O-N 2.94Å; V308-V311 PolarHBondContact O-N 2.86Å; V311-G315 PolarHBondContact O-N 2.93Å; V311-F358 HydrophobicContact CG1-CE1 4.29Å; V311-L359 HydrophobicContact CG1-CD2 3.78Å
312	F	92.8	Very high	90.7	Very high	0 Å²	0	27.7 Å²	27.7	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-76.1	-28.6	-179.4	-67.6	-64.4	0	0	0	113.2	L88 V308 G315 F316 G355 F358 L359 W371	L88-F312 HydrophobicContact CB-CB 4.47Å; L88-F312 HydrophobicContact CB-CD2 3.66Å; L88-F312 HydrophobicContact CB-CE2 4.12Å; L88-F312 HydrophobicContact CB-CG 4.1Å; L88-F312 HydrophobicContact CD1-CD1 4.05Å; L88-F312 HydrophobicContact CD1-CD2 3.87Å; L88-F312 HydrophobicContact CD1-CE1 3.89Å; L88-F312 HydrophobicContact CD1-CE2 3.71Å; L88-F312 HydrophobicContact CD1-CG 4.05Å; L88-F312 HydrophobicContact CD1-CZ 3.71Å; L88-F312 HydrophobicContact CG-CB 4.15Å; L88-F312 HydrophobicContact CG-CD1 4.05Å; L88-F312 HydrophobicContact CG-CD2 3.66Å; L88-F312 HydrophobicContact CG-CE1 4.39Å; L88-F312 HydrophobicContact CG-CE2 4.05Å; L88-F312 HydrophobicContact CG-CG 3.67Å; L88-F312 HydrophobicContact CG-CZ 4.39Å; V308-F312 HydrophobicContact CG1-CD2 3.79Å; V308-F312 HydrophobicContact CG1-CE2 3.96Å; V308-F312 WeakPolarHBondContact O-CD2 3.2Å; V308-F312 PolarHBondContact O-N 2.88Å; V308-F312 VanDerWaalsContact O-N 3.12Å; F312-G315 PolarHBondContact O-N 3.3Å; F312-F316 HydrophobicContact CB-CD2 4.44Å; F312-F316 AromaticContact CD1-CD2 3.88Å; F312-F316 HydrophobicContact CD1-CD2 3.88Å; F312-F316 AromaticContact CD1-CE2 3.75Å; F312-F316 HydrophobicContact CD1-CE2 3.75Å; F312-F316 HydrophobicContact CE1-CE2 4.24Å; F312-F316 PolarHBondContact O-N 2.87Å; F312-G355 VanDerWaalsContact CE1-CA 3.4Å; F312-F358 AromaticContact CD1-CD1 3.95Å; F312-F358 HydrophobicContact CD1-CD1 3.95Å; F312-F358 HydrophobicContact CD1-CE1 4.4Å; F312-F358 AromaticContact CE1-CD1 3.82Å; F312-F358 HydrophobicContact CE1-CD1 3.82Å; F312-L359 HydrophobicContact CE1-CD2 4.49Å; F312-L359 HydrophobicContact CE1-CG 4.25Å; F312-L359 HydrophobicContact CZ-CD1 3.94Å; F312-L359 HydrophobicContact CZ-CD2 4.42Å; F312-L359 HydrophobicContact CZ-CG 4.09Å; F312-W371 AromaticContact CE2-CH2 3.7Å; F312-W371 HydrophobicContact CE2-CH2 3.7Å; F312-W371 AromaticContact CE2-CZ3 3.77Å; F312-W371 HydrophobicContact CE2-CZ3 3.77Å; F312-W371 HydrophobicContact CZ-CE3 4.46Å; F312-W371 AromaticContact CZ-CH2 3.82Å; F312-W371 HydrophobicContact CZ-CH2 3.82Å; F312-W371 HydrophobicContact CZ-CZ2 4.32Å; F312-W371 AromaticContact CZ-CZ3 3.9Å; F312-W371 HydrophobicContact CZ-CZ3 3.9Å
313	G	92.6	Very high	90.1	Very high	2 Å²	2	31.8 Å²	31.8	2%	0.021	18%	0.175	C	C	.	.	H	α-helix	trans	-63.2	-45.3	170.2	0	0	0	0	0	113	G91 V309 G315 Y317	G91-G313 VanDerWaalsContact C-CA 3.47Å; G91-G313 VanDerWaalsContact O-CA 3.24Å; G91-G313 WeakPolarHBondContact O-CA 3.45Å; V309-G313 WeakPolarHBondContact O-CA 3.34Å; V309-G313 PolarHBondContact O-N 3.23Å; G313-G315 VanDerWaalsContact C-N 3.3Å; G313-G315 PolarHBondContact O-N 3.28Å; G313-Y317 WeakPolarHBondContact O-CB 3.42Å; G313-Y317 PolarHBondContact O-N 3.27Å
314	A	90.9	Very high	89.5	Confident	39 Å²	39	29.6 Å²	29.6	32%	0.322	17%	0.165	S	C	.	.	H	α-helix	trans	-66.6	-33.2	173.8	0	0	0	0	0	112.8	V223 S310	V223-A314 HydrophobicContact CG1-CB 3.5Å; S310-A314 WeakPolarHBondContact O-CB 3.46Å; S310-A314 PolarHBondContact O-N 2.81Å; S310-A314 VanDerWaalsContact O-N 3.07Å
315	G	87.9	Confident	88.9	Confident	4 Å²	4	30 Å²	30	4%	0.041	17%	0.167	C	C	.	.	H	α-helix	trans	-72.9	-57.3	-178.2	0	0	0	0	0	114.3	V311 F312 G313 K319	V311-G315 PolarHBondContact O-N 2.93Å; F312-G315 PolarHBondContact O-N 3.3Å; G313-G315 VanDerWaalsContact C-N 3.3Å; G313-G315 PolarHBondContact O-N 3.28Å; G315-K319 WeakPolarHBondContact O-CD 3.39Å; G315-K319 PolarHBondContact O-NZ 3.33Å
316	F	90.2	Very high	88.2	Confident	3 Å²	3	34.8 Å²	34.8	1%	0.013	19%	0.189	C	C	.	.	H	α-helix	trans	-103.4	-21	-166.7	-74.6	-74.5	0	0	0	114.9	A92 F312 G318 K319 V321 V324 V350 F358	A92-F316 HydrophobicContact CB-CB 3.78Å; F312-F316 HydrophobicContact CB-CD2 4.44Å; F312-F316 AromaticContact CD1-CD2 3.88Å; F312-F316 HydrophobicContact CD1-CD2 3.88Å; F312-F316 AromaticContact CD1-CE2 3.75Å; F312-F316 HydrophobicContact CD1-CE2 3.75Å; F312-F316 HydrophobicContact CE1-CE2 4.24Å; F312-F316 PolarHBondContact O-N 2.87Å; F316-G318 PolarHBondContact O-N 2.91Å; F316-G318 VanDerWaalsContact O-N 3.14Å; F316-K319 PolarHBondContact O-N 3.5Å; F316-K319 VanDerWaalsContact O-O 3.13Å; F316-V321 HydrophobicContact CD1-CG2 4.08Å; F316-V321 HydrophobicContact CE1-CB 4.34Å; F316-V321 HydrophobicContact CE1-CG1 4.27Å; F316-V321 HydrophobicContact CE1-CG2 3.91Å; F316-V324 HydrophobicContact CD1-CG2 4.16Å; F316-V324 HydrophobicContact CE1-CB 4.26Å; F316-V324 HydrophobicContact CE1-CG1 4.2Å; F316-V324 HydrophobicContact CE1-CG2 4.37Å; F316-V350 HydrophobicContact CB-CG2 4.09Å; F316-V350 HydrophobicContact CD1-CG1 4.36Å; F316-V350 HydrophobicContact CD1-CG2 3.98Å; F316-V350 HydrophobicContact CD2-CG1 3.69Å; F316-V350 HydrophobicContact CD2-CG2 4.25Å; F316-V350 HydrophobicContact CE1-CG1 4.23Å; F316-V350 HydrophobicContact CE1-CG2 4.45Å; F316-V350 HydrophobicContact CE2-CG1 3.51Å; F316-V350 HydrophobicContact CG-CG1 4.11Å; F316-V350 HydrophobicContact CG-CG2 3.86Å; F316-V350 HydrophobicContact CZ-CG1 3.79Å; F316-F358 HydrophobicContact CD2-CG 4.47Å; F316-F358 HydrophobicContact CE2-CB 3.63Å; F316-F358 HydrophobicContact CE2-CD1 4.07Å; F316-F358 HydrophobicContact CE2-CD2 4.25Å; F316-F358 AromaticContact CE2-CG 3.7Å; F316-F358 HydrophobicContact CE2-CG 3.7Å; F316-F358 HydrophobicContact CZ-CB 3.52Å; F316-F358 HydrophobicContact CZ-CD2 4.28Å; F316-F358 AromaticContact CZ-CG 3.94Å; F316-F358 HydrophobicContact CZ-CG 3.94Å
317	Y	87.7	Confident	87.6	Confident	76 Å²	76	38.9 Å²	38.9	30%	0.298	21%	0.211	S	C	.	.	T	Hydrogen-bonded Turn	trans	-60	123.1	-173.4	-175.8	-102.7	0	0	0	112.3	A92 I93 N95 R97 G313 K319	A92-Y317 WeakPolarHBondContact O-CA 3.17Å; I93-Y317 WeakPolarHBondContact O-CE2 3.27Å; N95-Y317 HydrophobicContact CB-CD1 3.85Å; N95-Y317 HydrophobicContact CB-CD2 3.53Å; N95-Y317 HydrophobicContact CB-CE1 4.06Å; N95-Y317 HydrophobicContact CB-CE2 3.72Å; N95-Y317 HydrophobicContact CB-CG 3.57Å; R97-Y317 PolarHBondContact NH2-OH 2.9Å; G313-Y317 WeakPolarHBondContact O-CB 3.42Å; G313-Y317 PolarHBondContact O-N 3.27Å; Y317-K319 VanDerWaalsContact C-N 3.29Å; Y317-K319 PolarHBondContact O-N 3.43Å
318	G	86.1	Confident	86.8	Confident	77 Å²	77	37.2 Å²	37.2	79%	0.794	21%	0.205	S	C	*	.	T	Hydrogen-bonded Turn	trans	75	9.8	-177.9	0	0	0	0	0	115.3	F316	F316-G318 PolarHBondContact O-N 2.91Å; F316-G318 VanDerWaalsContact O-N 3.14Å
319	K	86.9	Confident	86	Confident	101 Å²	101	40 Å²	40	44%	0.439	22%	0.222	S	C	.	.	S	Bend	trans	-122	145.7	177.4	-54.2	179.4	-161.6	153.7	0	110.2	G315 F316 Y317 V324	G315-K319 WeakPolarHBondContact O-CD 3.39Å; G315-K319 PolarHBondContact O-NZ 3.33Å; F316-K319 PolarHBondContact O-N 3.5Å; F316-K319 VanDerWaalsContact O-O 3.13Å; Y317-K319 VanDerWaalsContact C-N 3.29Å; Y317-K319 PolarHBondContact O-N 3.43Å; K319-V324 HydrophobicContact CB-CG2 3.67Å; K319-V324 HydrophobicContact CD-CG2 3.82Å; K319-V324 HydrophobicContact CG-CG2 4.42Å
320	N	83.9	Confident	85.3	Confident	69 Å²	69	49.4 Å²	49.4	37%	0.369	26%	0.257	S	S	.	.			trans	-79.7	142.5	171.2	-65.7	-18.2	0	0	0	109.9	K322 Q323 V324	N320-K322 PolarHBondContact O-N 3.31Å; N320-Q323 HydrophobicContact CB-CB 4.42Å; N320-Q323 HydrophobicContact CB-CG 4.06Å; N320-Q323 WeakPolarHBondContact O-CB 3.33Å; N320-Q323 PolarHBondContact O-N 2.75Å; N320-V324 PolarHBondContact O-N 3.45Å; N320-V324 VanDerWaalsContact O-N 3.1Å
321	V	82.4	Confident	84.5	Confident	3 Å²	3	55.1 Å²	55.1	2%	0.018	28%	0.284	C	S	.	.	H	α-helix	trans	-54.2	-43.5	179.2	175.3	0	0	0	0	111	F316 Q323 V324 I325 P347 V350 T354	F316-V321 HydrophobicContact CD1-CG2 4.08Å; F316-V321 HydrophobicContact CE1-CB 4.34Å; F316-V321 HydrophobicContact CE1-CG1 4.27Å; F316-V321 HydrophobicContact CE1-CG2 3.91Å; V321-Q323 VanDerWaalsContact C-N 3.32Å; V321-Q323 PolarHBondContact O-N 2.76Å; V321-V324 PolarHBondContact O-N 3.36Å; V321-I325 HydrophobicContact CG1-CD1 3.57Å; V321-I325 HydrophobicContact CG1-CG1 4.26Å; V321-I325 WeakPolarHBondContact O-CB 3.12Å; V321-I325 VanDerWaalsContact O-CG1 3.29Å; V321-I325 WeakPolarHBondContact O-CG1 3.33Å; V321-I325 PolarHBondContact O-N 3.01Å; V321-P347 PolarHBondContact N-O 2.93Å; V321-V350 HydrophobicContact CG2-CG2 3.82Å; V321-T354 HydrophobicContact CG1-CG2 3.69Å
322	K	80.9	Confident	83.7	Confident	82 Å²	82	58 Å²	58	36%	0.357	31%	0.314	S	S	.	.	H	α-helix	trans	-58.6	-40.8	176.2	-71.6	-175	-177.1	-174	0	112.9	N320 I325 E326 S343 P347	N320-K322 PolarHBondContact O-N 3.31Å; K322-I325 PolarHBondContact O-N 2.92Å; K322-E326 WeakPolarHBondContact O-CB 3.21Å; K322-E326 WeakPolarHBondContact O-CG 3.26Å; K322-E326 PolarHBondContact O-N 2.91Å; K322-S343 VanDerWaalsContact CE-O 3.3Å; K322-S343 WeakPolarHBondContact CE-O 3.45Å; K322-S343 PolarHBondContact NZ-O 3.23Å; K322-P347 HydrophobicContact CB-CB 4.37Å; K322-P347 HydrophobicContact CD-CB 3.91Å; K322-P347 HydrophobicContact CD-CG 4.38Å; K322-P347 HydrophobicContact CG-CB 3.89Å
323	Q	82.1	Confident	82.9	Confident	99 Å²	99	62.6 Å²	62.6	46%	0.463	33%	0.333	S	S	.	.	H	α-helix	trans	-67.2	-41.5	178.8	-68.4	172.3	-25	0	0	111.8	N320 V321 N327	N320-Q323 HydrophobicContact CB-CB 4.42Å; N320-Q323 HydrophobicContact CB-CG 4.06Å; N320-Q323 WeakPolarHBondContact O-CB 3.33Å; N320-Q323 PolarHBondContact O-N 2.75Å; V321-Q323 VanDerWaalsContact C-N 3.32Å; V321-Q323 PolarHBondContact O-N 2.76Å; Q323-N327 WeakPolarHBondContact O-CB 3.21Å; Q323-N327 VanDerWaalsContact O-CG 3.3Å; Q323-N327 PolarHBondContact O-N 2.95Å; Q323-N327 VanDerWaalsContact O-N 3.12Å; Q323-N327 PolarHBondContact O-ND2 3.07Å
324	V	82.1	Confident	82.3	Confident	11 Å²	11	63.1 Å²	63.1	7%	0.067	34%	0.336	C	S	.	.	H	α-helix	trans	-62.4	-45.9	177.4	177.6	0	0	0	0	110.2	F316 K319 N320 V321 C328 F358	F316-V324 HydrophobicContact CD1-CG2 4.16Å; F316-V324 HydrophobicContact CE1-CB 4.26Å; F316-V324 HydrophobicContact CE1-CG1 4.2Å; F316-V324 HydrophobicContact CE1-CG2 4.37Å; K319-V324 HydrophobicContact CB-CG2 3.67Å; K319-V324 HydrophobicContact CD-CG2 3.82Å; K319-V324 HydrophobicContact CG-CG2 4.42Å; N320-V324 PolarHBondContact O-N 3.45Å; N320-V324 VanDerWaalsContact O-N 3.1Å; V321-V324 PolarHBondContact O-N 3.36Å; V324-C328 PolarHBondContact O-N 3.36Å; V324-F358 HydrophobicContact CG1-CD2 3.66Å; V324-F358 HydrophobicContact CG1-CE2 4.21Å
325	I	81.5	Confident	81.8	Confident	9 Å²	9	63.7 Å²	63.7	5%	0.046	34%	0.336	C	S	.	.	H	α-helix	trans	-73.4	-37.8	-177.8	-63.2	-179.8	0	0	0	112	V321 K322 C328 T329 T339 A342 T354 I357	V321-I325 HydrophobicContact CG1-CD1 3.57Å; V321-I325 HydrophobicContact CG1-CG1 4.26Å; V321-I325 WeakPolarHBondContact O-CB 3.12Å; V321-I325 VanDerWaalsContact O-CG1 3.29Å; V321-I325 WeakPolarHBondContact O-CG1 3.33Å; V321-I325 PolarHBondContact O-N 3.01Å; K322-I325 PolarHBondContact O-N 2.92Å; I325-C328 WeakPolarHBondContact O-CB 3.44Å; I325-C328 PolarHBondContact O-N 3.49Å; I325-T329 WeakPolarHBondContact O-CB 3.14Å; I325-T329 PolarHBondContact O-N 2.82Å; I325-T329 PolarHBondContact O-OG1 3Å; I325-T339 HydrophobicContact CG2-CG2 4.1Å; I325-A342 HydrophobicContact CD1-CB 3.46Å; I325-A342 VanDerWaalsContact CD1-CB 3.46Å; I325-A342 HydrophobicContact CG2-CB 4.34Å; I325-T354 HydrophobicContact CD1-CG2 4.36Å; I325-I357 HydrophobicContact CD1-CG2 4.28Å; I325-I357 HydrophobicContact CG1-CG2 4.32Å; I325-I357 HydrophobicContact CG2-CG2 4.49Å
326	E	81	Confident	81.4	Confident	102 Å²	102	67.9 Å²	67.9	48%	0.477	36%	0.361	S	S	.	.	H	α-helix	trans	-62.4	-42.7	175.4	-79.9	173.2	-164.7	0	0	111.7	K322 C328 T329 R330	K322-E326 WeakPolarHBondContact O-CB 3.21Å; K322-E326 WeakPolarHBondContact O-CG 3.26Å; K322-E326 PolarHBondContact O-N 2.91Å; E326-C328 VanDerWaalsContact C-N 3.34Å; E326-C328 PolarHBondContact O-N 2.76Å; E326-T329 PolarHBondContact O-N 3.47Å; E326-R330 WeakPolarHBondContact O-CG 3.27Å; E326-R330 PolarHBondContact O-N 3.3Å; E326-R330 VanDerWaalsContact O-N 3.08Å
327	N	81.4	Confident	80.9	Confident	94 Å²	94	73.7 Å²	73.7	50%	0.503	38%	0.383	S	S	.	.	H	α-helix	trans	-60.7	-45.4	175.6	-76.8	-13.9	0	0	0	111.3	Q323 T329 R330	Q323-N327 WeakPolarHBondContact O-CB 3.21Å; Q323-N327 VanDerWaalsContact O-CG 3.3Å; Q323-N327 PolarHBondContact O-N 2.95Å; Q323-N327 VanDerWaalsContact O-N 3.12Å; Q323-N327 PolarHBondContact O-ND2 3.07Å; N327-T329 PolarHBondContact O-N 3.35Å; N327-R330 PolarHBondContact O-N 3.06Å
328	C	78.4	Confident	80.6	Confident	8 Å²	8	70.1 Å²	70.1	5%	0.054	37%	0.369	C	S	.	.	H	α-helix	trans	-62.2	-40.4	174.6	168.3	0	0	0	0	113.5	V324 I325 E326 R330 E331 G332 C361	V324-C328 PolarHBondContact O-N 3.36Å; I325-C328 WeakPolarHBondContact O-CB 3.44Å; I325-C328 PolarHBondContact O-N 3.49Å; E326-C328 VanDerWaalsContact C-N 3.34Å; E326-C328 PolarHBondContact O-N 2.76Å; C328-R330 VanDerWaalsContact C-N 3.26Å; C328-R330 PolarHBondContact O-N 2.73Å; C328-E331 PolarHBondContact O-N 2.92Å; C328-E331 VanDerWaalsContact O-N 3.11Å; C328-G332 PolarHBondContact O-N 3.26Å; C328-C361 HydrophobicContact CB-CB 3.44Å; C328-C361 VanDerWaalsContact CB-CB 3.44Å; C328-C361 WeakPolarHBondContact CB-SG 3.24Å; C328-C361 WeakPolarHBondContact SG-CA 3.34Å; C328-C361 WeakPolarHBondContact SG-CB 3.45Å; C328-C361 CovalentContact SG-SG 2Å; C328-C361 PolarHBondContact SG-SG 3.24Å
329	T	77.1	Confident	79.9	Confident	60 Å²	60	66.8 Å²	66.8	37%	0.368	33%	0.333	S	S	.	.	H	α-helix	trans	-62.9	-36.9	179.9	-54.6	0	0	0	0	110.8	I325 E326 N327 E331 G332 T339	I325-T329 WeakPolarHBondContact O-CB 3.14Å; I325-T329 PolarHBondContact O-N 2.82Å; I325-T329 PolarHBondContact O-OG1 3Å; E326-T329 PolarHBondContact O-N 3.47Å; N327-T329 PolarHBondContact O-N 3.35Å; T329-E331 PolarHBondContact O-N 2.88Å; T329-G332 PolarHBondContact O-N 3.28Å; T329-G332 VanDerWaalsContact O-N 3.09Å; T329-T339 HydrophobicContact CG2-CG2 4.38Å; T329-T339 VanDerWaalsContact OG1-CG2 3.25Å; T329-T339 WeakPolarHBondContact OG1-CG2 3.25Å
330	R	79.2	Confident	79.4	Confident	198 Å²	198	66.9 Å²	66.9	75%	0.747	34%	0.338	S	S	*	.	H	α-helix	trans	-63.3	-29.1	176.1	-71.2	174.5	-175.2	179.9	4.3	113.1	E326 N327 C328 G332	E326-R330 WeakPolarHBondContact O-CG 3.27Å; E326-R330 PolarHBondContact O-N 3.3Å; E326-R330 VanDerWaalsContact O-N 3.08Å; N327-R330 PolarHBondContact O-N 3.06Å; C328-R330 VanDerWaalsContact C-N 3.26Å; C328-R330 PolarHBondContact O-N 2.73Å; R330-G332 VanDerWaalsContact C-N 3.31Å
331	E	77.4	Confident	78.9	Confident	121 Å²	121	64.9 Å²	64.9	57%	0.565	33%	0.332	S	S	*	.	H	α-helix	trans	-80.3	-12.1	176.8	-62.4	-175.6	163.2	0	0	113	C328 T329 K333	C328-E331 PolarHBondContact O-N 2.92Å; C328-E331 VanDerWaalsContact O-N 3.11Å; T329-E331 PolarHBondContact O-N 2.88Å; E331-K333 VanDerWaalsContact C-N 3.27Å; E331-K333 HydrophobicContact CB-CD 4.21Å; E331-K333 HydrophobicContact CB-CG 4.03Å; E331-K333 PolarHBondContact O-N 2.9Å; E331-K333 WeakPolarHBondContact OE2-CD 2.98Å; E331-K333 WeakPolarHBondContact OE2-CE 3.48Å; E331-K333 IonicContact OE2-NZ 2.65Å; E331-K333 PolarHBondContact OE2-NZ 3.37Å
332	G	75.7	Confident	78.5	Confident	61 Å²	61	64.9 Å²	64.9	63%	0.629	33%	0.332	S	S	*	.	T	Hydrogen-bonded Turn	trans	68.8	20.6	177	0	0	0	0	0	114.6	C328 T329 R330	C328-G332 PolarHBondContact O-N 3.26Å; T329-G332 PolarHBondContact O-N 3.28Å; T329-G332 VanDerWaalsContact O-N 3.09Å; R330-G332 VanDerWaalsContact C-N 3.31Å
333	K	75.1	Confident	77.8	Confident	95 Å²	95	64 Å²	64	41%	0.413	34%	0.336	S	S	.	.			trans	-76.4	-20.6	-174.1	-71.3	178.5	174.4	166.4	0	114.7	E331 C361	E331-K333 VanDerWaalsContact C-N 3.27Å; E331-K333 HydrophobicContact CB-CD 4.21Å; E331-K333 HydrophobicContact CB-CG 4.03Å; E331-K333 PolarHBondContact O-N 2.9Å; E331-K333 WeakPolarHBondContact OE2-CD 2.98Å; E331-K333 WeakPolarHBondContact OE2-CE 3.48Å; E331-K333 IonicContact OE2-NZ 2.65Å; E331-K333 PolarHBondContact OE2-NZ 3.37Å; K333-C361 WeakPolarHBondContact CD-O 3.04Å; K333-C361 PolarHBondContact NZ-O 3.24Å
334	I	80.5	Confident	77.2	Confident	14 Å²	14	62 Å²	62	7%	0.072	33%	0.333	C	S	.	.	S	Bend	trans	-128.1	143.6	-173.7	-61.8	-169.7	0	0	0	110.9	V336 F338 I357 G360 C361 L365 L368	I334-V336 PolarHBondContact O-N 3.41Å; I334-F338 HydrophobicContact CG2-CB 3.68Å; I334-F338 HydrophobicContact CG2-CD2 3.33Å; I334-F338 HydrophobicContact CG2-CE2 4.26Å; I334-F338 HydrophobicContact CG2-CG 3.93Å; I334-I357 HydrophobicContact CD1-CG2 4.05Å; I334-I357 VanDerWaalsContact CD1-O 3.25Å; I334-I357 WeakPolarHBondContact CD1-O 3.31Å; I334-G360 VanDerWaalsContact CD1-C 3.48Å; I334-C361 HydrophobicContact CD1-CB 4.17Å; I334-C361 WeakPolarHBondContact CD1-SG 3.26Å; I334-L365 HydrophobicContact CG1-CD2 4.33Å; I334-L368 HydrophobicContact CD1-CD1 4.43Å
335	P	81.2	Confident	76.7	Confident	50 Å²	50	61.6 Å²	61.6	33%	0.325	33%	0.33	S	S	.	.			trans	-51.3	133.3	170.3	-27.6	32.8	0	0	0	114	V171 R337 F338	V171-P335 HydrophobicContact CG1-CB 4.14Å; V171-P335 HydrophobicContact CG1-CG 4.02Å; P335-R337 PolarHBondContact O-N 2.95Å; P335-F338 HydrophobicContact CB-CD2 3.87Å; P335-F338 HydrophobicContact CB-CE2 4.26Å; P335-F338 HydrophobicContact CG-CD2 3.97Å; P335-F338 HydrophobicContact CG-CE2 3.95Å; P335-F338 WeakPolarHBondContact O-CB 3.26Å; P335-F338 PolarHBondContact O-N 3.5Å
336	V	78.3	Confident	76.3	Confident	93 Å²	93	64.8 Å²	64.8	56%	0.564	35%	0.347	S	S	*	.	H	α-helix	trans	-55.1	-26.5	-177.1	-178.1	0	0	0	0	113.8	I334 F338 T339 N340	I334-V336 PolarHBondContact O-N 3.41Å; V336-F338 VanDerWaalsContact C-N 3.28Å; V336-F338 PolarHBondContact O-N 3.16Å; V336-T339 PolarHBondContact O-N 3.35Å; V336-T339 PolarHBondContact O-OG1 2.82Å; V336-N340 WeakPolarHBondContact O-CB 3.34Å; V336-N340 VanDerWaalsContact O-CG 3.24Å; V336-N340 PolarHBondContact O-N 3.39Å
337	R	79.9	Confident	75.8	Confident	124 Å²	124	61.7 Å²	61.7	47%	0.468	34%	0.336	S	S	.	.	H	α-helix	trans	-61.3	-38.1	177.6	-70.3	-172.7	178.9	-158.4	2.8	112.8	P335 A341	P335-R337 PolarHBondContact O-N 2.95Å; R337-A341 PolarHBondContact O-N 2.95Å; R337-A341 VanDerWaalsContact O-N 3.14Å
338	F	80.9	Confident	75.4	Confident	1 Å²	1	62.7 Å²	62.7	0%	0.004	34%	0.341	C	S	.	.	H	α-helix	trans	-67.3	-43	178.8	-69.9	-51.7	0	0	0	111.6	L168 V171 I334 P335 V336 A341 A342 Y353 I357 L368	L168-F338 HydrophobicContact CD2-CD1 4.18Å; L168-F338 HydrophobicContact CD2-CE1 3.96Å; V171-F338 VanDerWaalsContact CA-CZ 3.46Å; V171-F338 HydrophobicContact CB-CZ 4.13Å; V171-F338 HydrophobicContact CG1-CE2 3.76Å; V171-F338 HydrophobicContact CG1-CZ 3.84Å; I334-F338 HydrophobicContact CG2-CB 3.68Å; I334-F338 HydrophobicContact CG2-CD2 3.33Å; I334-F338 HydrophobicContact CG2-CE2 4.26Å; I334-F338 HydrophobicContact CG2-CG 3.93Å; P335-F338 HydrophobicContact CB-CD2 3.87Å; P335-F338 HydrophobicContact CB-CE2 4.26Å; P335-F338 HydrophobicContact CG-CD2 3.97Å; P335-F338 HydrophobicContact CG-CE2 3.95Å; P335-F338 WeakPolarHBondContact O-CB 3.26Å; P335-F338 PolarHBondContact O-N 3.5Å; V336-F338 VanDerWaalsContact C-N 3.28Å; V336-F338 PolarHBondContact O-N 3.16Å; F338-A341 PolarHBondContact O-N 2.99Å; F338-A342 VanDerWaalsContact O-CB 3.31Å; F338-A342 WeakPolarHBondContact O-CB 3.48Å; F338-A342 PolarHBondContact O-N 3.39Å; F338-Y353 PolarHBondContact O-OH 2.91Å; F338-I357 HydrophobicContact CB-CD1 3.65Å; F338-I357 HydrophobicContact CD1-CD1 3.94Å; F338-I357 HydrophobicContact CG-CD1 3.92Å; F338-L368 HydrophobicContact CE2-CD1 4.29Å; F338-L368 HydrophobicContact CZ-CD1 4.42Å; F338-L368 HydrophobicContact CZ-CD2 4.12Å
339	T	72.3	Confident	75.4	Confident	8 Å²	8	63.6 Å²	63.6	5%	0.049	35%	0.348	C	S	.	.	H	α-helix	trans	-72.9	-35.6	-178.1	59.4	0	0	0	0	111.5	I325 T329 V336 A342 S343	I325-T339 HydrophobicContact CG2-CG2 4.1Å; T329-T339 HydrophobicContact CG2-CG2 4.38Å; T329-T339 VanDerWaalsContact OG1-CG2 3.25Å; T329-T339 WeakPolarHBondContact OG1-CG2 3.25Å; V336-T339 PolarHBondContact O-N 3.35Å; V336-T339 PolarHBondContact O-OG1 2.82Å; T339-A342 PolarHBondContact O-N 2.96Å; T339-S343 WeakPolarHBondContact O-CB 3.35Å; T339-S343 PolarHBondContact O-N 3.46Å
340	N	75.9	Confident	75.8	Confident	102 Å²	102	61.2 Å²	61.2	55%	0.545	33%	0.333	S	S	.	.	H	α-helix	trans	-61.1	-47	172.5	-74.8	-7.9	0	0	0	111.8	V336 S343	V336-N340 WeakPolarHBondContact O-CB 3.34Å; V336-N340 VanDerWaalsContact O-CG 3.24Å; V336-N340 PolarHBondContact O-N 3.39Å; N340-S343 PolarHBondContact O-N 3.44Å; N340-S343 PolarHBondContact O-OG 2.69Å
341	A	74	Confident	76.2	Confident	28 Å²	28	52 Å²	52	23%	0.231	30%	0.298	C	S	.	.	H	α-helix	trans	-62.3	-49.3	174.6	0	0	0	0	0	110.4	R337 F338 S343 S344 F345 Y353	R337-A341 PolarHBondContact O-N 2.95Å; R337-A341 VanDerWaalsContact O-N 3.14Å; F338-A341 PolarHBondContact O-N 2.99Å; A341-S343 PolarHBondContact O-N 3.24Å; A341-S343 VanDerWaalsContact O-N 3.11Å; A341-S344 PolarHBondContact O-N 2.96Å; A341-S344 PolarHBondContact O-OG 3.43Å; A341-F345 WeakPolarHBondContact O-CD2 3.35Å; A341-F345 WeakPolarHBondContact O-CE2 3.32Å; A341-Y353 HydrophobicContact CB-CE1 3.98Å; A341-Y353 VanDerWaalsContact CB-OH 3.32Å; A341-Y353 WeakPolarHBondContact CB-OH 3.46Å
342	A	72.9	Confident	76.8	Confident	2 Å²	2	46.2 Å²	46.2	2%	0.017	27%	0.271	C	S	.	.	H	α-helix	trans	-60.4	-26.4	-178.9	0	0	0	0	0	113.8	I325 F338 T339 S344 F345 Y353 I357	I325-A342 HydrophobicContact CD1-CB 3.46Å; I325-A342 VanDerWaalsContact CD1-CB 3.46Å; I325-A342 HydrophobicContact CG2-CB 4.34Å; F338-A342 VanDerWaalsContact O-CB 3.31Å; F338-A342 WeakPolarHBondContact O-CB 3.48Å; F338-A342 PolarHBondContact O-N 3.39Å; T339-A342 PolarHBondContact O-N 2.96Å; A342-S344 VanDerWaalsContact C-N 3.27Å; A342-S344 PolarHBondContact O-N 3.33Å; A342-F345 VanDerWaalsContact CA-CD2 3.41Å; A342-F345 WeakPolarHBondContact O-CD2 3.35Å; A342-F345 PolarHBondContact O-N 2.94Å; A342-Y353 HydrophobicContact CB-CD1 4.41Å; A342-Y353 HydrophobicContact CB-CE1 3.99Å; A342-I357 HydrophobicContact CB-CG1 4.34Å
343	S	67.3	Low	77.4	Confident	64 Å²	64	43.4 Å²	43.4	45%	0.448	24%	0.242	S	C	.	.	T	Hydrogen-bonded Turn	trans	-69.5	-19.6	177.8	75.9	0	0	0	0	114.5	K322 T339 N340 A341 F345	K322-S343 VanDerWaalsContact CE-O 3.3Å; K322-S343 WeakPolarHBondContact CE-O 3.45Å; K322-S343 PolarHBondContact NZ-O 3.23Å; T339-S343 WeakPolarHBondContact O-CB 3.35Å; T339-S343 PolarHBondContact O-N 3.46Å; N340-S343 PolarHBondContact O-N 3.44Å; N340-S343 PolarHBondContact O-OG 2.69Å; A341-S343 PolarHBondContact O-N 3.24Å; A341-S343 VanDerWaalsContact O-N 3.11Å; S343-F345 VanDerWaalsContact C-N 3.34Å
344	S	69.6	Low	78.1	Confident	56 Å²	56	38.9 Å²	38.9	39%	0.392	22%	0.222	S	C	.	.	T	Hydrogen-bonded Turn	trans	-78.4	-20.3	176.7	77.7	0	0	0	0	113.1	A341 A342 E429	A341-S344 PolarHBondContact O-N 2.96Å; A341-S344 PolarHBondContact O-OG 3.43Å; A342-S344 VanDerWaalsContact C-N 3.27Å; A342-S344 PolarHBondContact O-N 3.33Å; S344-E429 PolarHBondContact OG-OE2 3.34Å
345	F	72.1	Confident	78.5	Confident	4 Å²	4	38.2 Å²	38.2	2%	0.018	22%	0.219	C	C	.	.	S	Bend	trans	-70.2	155.5	-177.9	-65.4	-104.1	0	0	0	111.6	A341 A342 S343 P347 D351 Y353 T354 I428	A341-F345 WeakPolarHBondContact O-CD2 3.35Å; A341-F345 WeakPolarHBondContact O-CE2 3.32Å; A342-F345 VanDerWaalsContact CA-CD2 3.41Å; A342-F345 WeakPolarHBondContact O-CD2 3.35Å; A342-F345 PolarHBondContact O-N 2.94Å; S343-F345 VanDerWaalsContact C-N 3.34Å; F345-P347 WeakPolarHBondContact O-CD 3.26Å; F345-D351 WeakPolarHBondContact CD1-OD2 3.44Å; F345-D351 WeakPolarHBondContact CE1-OD2 3.44Å; F345-Y353 HydrophobicContact CD2-CD1 4.4Å; F345-Y353 HydrophobicContact CE1-CD1 4.36Å; F345-Y353 HydrophobicContact CE1-CG 4.46Å; F345-Y353 AromaticContact CE2-CD1 3.48Å; F345-Y353 HydrophobicContact CE2-CD1 3.48Å; F345-Y353 VanDerWaalsContact CE2-CD1 3.48Å; F345-Y353 AromaticContact CE2-CE1 3.85Å; F345-Y353 HydrophobicContact CE2-CE1 3.85Å; F345-Y353 HydrophobicContact CE2-CG 4.22Å; F345-Y353 AromaticContact CZ-CD1 3.43Å; F345-Y353 HydrophobicContact CZ-CD1 3.43Å; F345-Y353 VanDerWaalsContact CZ-CD1 3.43Å; F345-Y353 HydrophobicContact CZ-CE1 4.16Å; F345-Y353 AromaticContact CZ-CG 3.69Å; F345-Y353 HydrophobicContact CZ-CG 3.69Å; F345-T354 HydrophobicContact CB-CG2 4.35Å; F345-T354 HydrophobicContact CD1-CG2 4.48Å; F345-T354 HydrophobicContact CG-CG2 4.24Å; F345-I428 HydrophobicContact CD1-CG2 4.37Å; F345-I428 HydrophobicContact CE1-CB 4.49Å; F345-I428 HydrophobicContact CE1-CG2 3.37Å; F345-I428 HydrophobicContact CE2-CG2 4.17Å; F345-I428 HydrophobicContact CZ-CB 4.35Å; F345-I428 HydrophobicContact CZ-CG2 3.27Å
346	D	72.1	Confident	78.8	Confident	76 Å²	76	35.9 Å²	35.9	41%	0.406	20%	0.203	S	C	.	.			trans	-61.2	122.1	173.7	179	-8.4	0	0	0	109	N348 S349	D346-N348 PolarHBondContact O-N 2.77Å; D346-N348 PolarHBondContact OD1-N 3.49Å; D346-N348 PolarHBondContact OD1-ND2 3.3Å; D346-S349 WeakPolarHBondContact CB-OG 3.14Å; D346-S349 PolarHBondContact O-N 2.89Å; D346-S349 PolarHBondContact O-OG 3.28Å
347	P	71.4	Confident	79.3	Confident	36 Å²	36	31.4 Å²	31.4	23%	0.234	18%	0.177	C	C	.	.	T	Hydrogen-bonded Turn	trans	-58.7	-17.8	-178.7	22.7	-34.3	0	0	0	114.6	V321 K322 F345	V321-P347 PolarHBondContact N-O 2.93Å; K322-P347 HydrophobicContact CB-CB 4.37Å; K322-P347 HydrophobicContact CD-CB 3.91Å; K322-P347 HydrophobicContact CD-CG 4.38Å; K322-P347 HydrophobicContact CG-CB 3.89Å; F345-P347 WeakPolarHBondContact O-CD 3.26Å
348	N	72.6	Confident	79.7	Confident	116 Å²	116	25.8 Å²	25.8	62%	0.62	16%	0.156	S	C	*	.	T	Hydrogen-bonded Turn	trans	-99.7	-12.3	-175.1	-53.5	-53.5	0	0	0	113.5	D346	D346-N348 PolarHBondContact O-N 2.77Å; D346-N348 PolarHBondContact OD1-N 3.49Å; D346-N348 PolarHBondContact OD1-ND2 3.3Å
349	S	77.5	Confident	80	Confident	27 Å²	27	25.8 Å²	25.8	19%	0.189	16%	0.155	C	C	.	.			trans	-108	131	179.4	65.6	0	0	0	0	110.3	D346	D346-S349 WeakPolarHBondContact CB-OG 3.14Å; D346-S349 PolarHBondContact O-N 2.89Å; D346-S349 PolarHBondContact O-OG 3.28Å
350	V	85.6	Confident	80.7	Confident	10 Å²	10	25.4 Å²	25.4	6%	0.061	15%	0.153	C	C	.	.			trans	-100.1	139.2	172	-162.9	0	0	0	0	108.1	L88 Q89 A92 F316 V321	L88-V350 HydrophobicContact CD1-CG1 4.37Å; L88-V350 HydrophobicContact CD2-CB 3.55Å; L88-V350 HydrophobicContact CD2-CG1 3.32Å; L88-V350 HydrophobicContact CG-CG1 4.07Å; Q89-V350 VanDerWaalsContact CG-O 3.24Å; Q89-V350 WeakPolarHBondContact CG-O 3.48Å; Q89-V350 PolarHBondContact NE2-O 2.92Å; A92-V350 HydrophobicContact CB-CB 3.98Å; A92-V350 HydrophobicContact CB-CG2 3.37Å; F316-V350 HydrophobicContact CB-CG2 4.09Å; F316-V350 HydrophobicContact CD1-CG1 4.36Å; F316-V350 HydrophobicContact CD1-CG2 3.98Å; F316-V350 HydrophobicContact CD2-CG1 3.69Å; F316-V350 HydrophobicContact CD2-CG2 4.25Å; F316-V350 HydrophobicContact CE1-CG1 4.23Å; F316-V350 HydrophobicContact CE1-CG2 4.45Å; F316-V350 HydrophobicContact CE2-CG1 3.51Å; F316-V350 HydrophobicContact CG-CG1 4.11Å; F316-V350 HydrophobicContact CG-CG2 3.86Å; F316-V350 HydrophobicContact CZ-CG1 3.79Å; V321-V350 HydrophobicContact CG2-CG2 3.82Å
351	D	87.5	Confident	81.2	Confident	3 Å²	3	20.6 Å²	20.6	2%	0.016	13%	0.128	C	C	.	.			trans	-136.9	176.7	-175.6	79.7	-27.7	0	0	0	110.9	L88 F345 Y353 T354 G355 T432	L88-D351 WeakPolarHBondContact CD1-O 3.4Å; F345-D351 WeakPolarHBondContact CD1-OD2 3.44Å; F345-D351 WeakPolarHBondContact CE1-OD2 3.44Å; D351-Y353 PolarHBondContact O-N 3.39Å; D351-Y353 PolarHBondContact OD1-N 3.28Å; D351-Y353 WeakPolarHBondContact OD2-CB 3.38Å; D351-T354 PolarHBondContact N-OG1 2.93Å; D351-T354 PolarHBondContact O-N 2.84Å; D351-T354 PolarHBondContact O-OG1 3.32Å; D351-T354 WeakPolarHBondContact OD1-CB 3.33Å; D351-T354 WeakPolarHBondContact OD1-CG2 3.25Å; D351-T354 PolarHBondContact OD1-N 3.27Å; D351-T354 PolarHBondContact OD1-OG1 2.94Å; D351-G355 PolarHBondContact O-N 3.44Å; D351-T432 HydrophobicContact CB-CG2 3.97Å; D351-T432 WeakPolarHBondContact CB-OG1 3.4Å
352	L	89.9	Confident	81.6	Confident	0 Å²	0	24.2 Å²	24.2	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-60.9	-30.2	-179.7	-64.6	177.3	0	0	0	113	P81 I84 E85 I164 G356 W371 L375	P81-L352 HydrophobicContact CB-CD1 3.91Å; I84-L352 HydrophobicContact CB-CD2 4.33Å; I84-L352 HydrophobicContact CG2-CD2 3.82Å; E85-L352 HydrophobicContact CB-CD1 4.35Å; E85-L352 HydrophobicContact CB-CD2 3.77Å; E85-L352 HydrophobicContact CB-CG 3.87Å; E85-L352 HydrophobicContact CG-CD2 4.4Å; E85-L352 HydrophobicContact CG-CG 4.13Å; I164-L352 HydrophobicContact CD1-CB 3.87Å; I164-L352 HydrophobicContact CD1-CD1 4.47Å; I164-L352 HydrophobicContact CG2-CB 4.21Å; L352-G356 PolarHBondContact O-N 2.81Å; L352-W371 HydrophobicContact CD2-CH2 4.34Å; L352-W371 HydrophobicContact CD2-CZ2 3.84Å; L352-W371 PolarHBondContact O-NE1 3.47Å; L352-L375 HydrophobicContact CB-CD1 4.05Å; L352-L375 HydrophobicContact CD1-CD2 4.31Å; L352-L375 HydrophobicContact CD2-CD2 3.93Å
353	Y	89.3	Confident	82.1	Confident	3 Å²	3	26.5 Å²	26.5	1%	0.012	15%	0.149	C	C	.	.	H	α-helix	trans	-72.4	-56	179	-173.8	-97.2	0	0	0	111.5	I164 N167 L168 F338 A341 A342 F345 D351 G355 G356 I357	I164-Y353 HydrophobicContact CG2-CD2 4.24Å; N167-Y353 WeakPolarHBondContact OD1-CE2 3.3Å; L168-Y353 HydrophobicContact CD2-CD2 3.77Å; L168-Y353 HydrophobicContact CD2-CE2 3.45Å; L168-Y353 VanDerWaalsContact CD2-CE2 3.45Å; L168-Y353 HydrophobicContact CG-CD2 4.11Å; L168-Y353 HydrophobicContact CG-CE2 4.11Å; F338-Y353 PolarHBondContact O-OH 2.91Å; A341-Y353 HydrophobicContact CB-CE1 3.98Å; A341-Y353 VanDerWaalsContact CB-OH 3.32Å; A341-Y353 WeakPolarHBondContact CB-OH 3.46Å; A342-Y353 HydrophobicContact CB-CD1 4.41Å; A342-Y353 HydrophobicContact CB-CE1 3.99Å; F345-Y353 HydrophobicContact CD2-CD1 4.4Å; F345-Y353 HydrophobicContact CE1-CD1 4.36Å; F345-Y353 HydrophobicContact CE1-CG 4.46Å; F345-Y353 AromaticContact CE2-CD1 3.48Å; F345-Y353 HydrophobicContact CE2-CD1 3.48Å; F345-Y353 VanDerWaalsContact CE2-CD1 3.48Å; F345-Y353 AromaticContact CE2-CE1 3.85Å; F345-Y353 HydrophobicContact CE2-CE1 3.85Å; F345-Y353 HydrophobicContact CE2-CG 4.22Å; F345-Y353 AromaticContact CZ-CD1 3.43Å; F345-Y353 HydrophobicContact CZ-CD1 3.43Å; F345-Y353 VanDerWaalsContact CZ-CD1 3.43Å; F345-Y353 HydrophobicContact CZ-CE1 4.16Å; F345-Y353 AromaticContact CZ-CG 3.69Å; F345-Y353 HydrophobicContact CZ-CG 3.69Å; D351-Y353 PolarHBondContact O-N 3.39Å; D351-Y353 PolarHBondContact OD1-N 3.28Å; D351-Y353 WeakPolarHBondContact OD2-CB 3.38Å; Y353-G355 PolarHBondContact O-N 3.29Å; Y353-G356 PolarHBondContact O-N 2.99Å; Y353-I357 HydrophobicContact CD1-CG1 4.07Å; Y353-I357 HydrophobicContact CE1-CD1 4.09Å; Y353-I357 HydrophobicContact CE1-CG1 3.78Å; Y353-I357 WeakPolarHBondContact O-CG1 3.03Å; Y353-I357 PolarHBondContact O-N 3.46Å
354	T	88.7	Confident	83	Confident	0 Å²	0	24.6 Å²	24.6	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-61.8	-33	178.7	55.9	0	0	0	0	111.6	V321 I325 F345 D351 I357 F358	V321-T354 HydrophobicContact CG1-CG2 3.69Å; I325-T354 HydrophobicContact CD1-CG2 4.36Å; F345-T354 HydrophobicContact CB-CG2 4.35Å; F345-T354 HydrophobicContact CD1-CG2 4.48Å; F345-T354 HydrophobicContact CG-CG2 4.24Å; D351-T354 PolarHBondContact N-OG1 2.93Å; D351-T354 PolarHBondContact O-N 2.84Å; D351-T354 PolarHBondContact O-OG1 3.32Å; D351-T354 WeakPolarHBondContact OD1-CB 3.33Å; D351-T354 WeakPolarHBondContact OD1-CG2 3.25Å; D351-T354 PolarHBondContact OD1-N 3.27Å; D351-T354 PolarHBondContact OD1-OG1 2.94Å; T354-I357 PolarHBondContact O-N 3.48Å; T354-F358 WeakPolarHBondContact O-CB 3.35Å; T354-F358 PolarHBondContact O-N 3.1Å
355	G	88.8	Confident	83.9	Confident	0 Å²	0	25 Å²	25	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-58.1	-48.9	169.6	0	0	0	0	0	112.6	F312 D351 Y353 I357 F358 L359	F312-G355 VanDerWaalsContact CE1-CA 3.4Å; D351-G355 PolarHBondContact O-N 3.44Å; Y353-G355 PolarHBondContact O-N 3.29Å; G355-I357 VanDerWaalsContact C-N 3.34Å; G355-I357 PolarHBondContact O-N 3.18Å; G355-F358 WeakPolarHBondContact O-CB 3.35Å; G355-F358 PolarHBondContact O-N 3.24Å; G355-L359 WeakPolarHBondContact O-CG 3.21Å; G355-L359 PolarHBondContact O-N 3.42Å
356	G	89.1	Confident	84.5	Confident	0 Å²	0	28 Å²	28	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-62.2	-39.5	175.7	0	0	0	0	0	113.2	L352 Y353 L359 G360 L368	L352-G356 PolarHBondContact O-N 2.81Å; Y353-G356 PolarHBondContact O-N 2.99Å; G356-L359 PolarHBondContact O-N 3.12Å; G356-G360 PolarHBondContact O-N 3.27Å; G356-L368 WeakPolarHBondContact O-CD1 3.39Å; G356-L368 WeakPolarHBondContact O-CG 3.12Å
357	I	88.5	Confident	85.2	Confident	0 Å²	0	24.8 Å²	24.8	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-63.4	-46.1	175.4	-58.2	-38.9	0	0	0	110.6	L168 I325 I334 F338 A342 Y353 T354 G355 L359 G360 C361 L368	L168-I357 HydrophobicContact CD2-CD1 3.76Å; I325-I357 HydrophobicContact CD1-CG2 4.28Å; I325-I357 HydrophobicContact CG1-CG2 4.32Å; I325-I357 HydrophobicContact CG2-CG2 4.49Å; I334-I357 HydrophobicContact CD1-CG2 4.05Å; I334-I357 VanDerWaalsContact CD1-O 3.25Å; I334-I357 WeakPolarHBondContact CD1-O 3.31Å; F338-I357 HydrophobicContact CB-CD1 3.65Å; F338-I357 HydrophobicContact CD1-CD1 3.94Å; F338-I357 HydrophobicContact CG-CD1 3.92Å; A342-I357 HydrophobicContact CB-CG1 4.34Å; Y353-I357 HydrophobicContact CD1-CG1 4.07Å; Y353-I357 HydrophobicContact CE1-CD1 4.09Å; Y353-I357 HydrophobicContact CE1-CG1 3.78Å; Y353-I357 WeakPolarHBondContact O-CG1 3.03Å; Y353-I357 PolarHBondContact O-N 3.46Å; T354-I357 PolarHBondContact O-N 3.48Å; G355-I357 VanDerWaalsContact C-N 3.34Å; G355-I357 PolarHBondContact O-N 3.18Å; I357-L359 PolarHBondContact O-N 3.16Å; I357-G360 PolarHBondContact O-N 3.44Å; I357-G360 VanDerWaalsContact O-N 3.16Å; I357-C361 WeakPolarHBondContact O-CB 3.34Å; I357-C361 PolarHBondContact O-N 3.46Å; I357-C361 PolarHBondContact O-SG 2.82Å; I357-L368 HydrophobicContact CD1-CD1 3.92Å
358	F	88	Confident	86	Confident	6 Å²	6	23 Å²	23	3%	0.026	14%	0.135	C	C	.	.	H	α-helix	trans	-57.8	-46.1	176.8	168.5	-101	0	0	0	112.5	V311 F312 F316 V324 T354 G355 G360 C361 E362	V311-F358 HydrophobicContact CG1-CE1 4.29Å; F312-F358 AromaticContact CD1-CD1 3.95Å; F312-F358 HydrophobicContact CD1-CD1 3.95Å; F312-F358 HydrophobicContact CD1-CE1 4.4Å; F312-F358 AromaticContact CE1-CD1 3.82Å; F312-F358 HydrophobicContact CE1-CD1 3.82Å; F316-F358 HydrophobicContact CD2-CG 4.47Å; F316-F358 HydrophobicContact CE2-CB 3.63Å; F316-F358 HydrophobicContact CE2-CD1 4.07Å; F316-F358 HydrophobicContact CE2-CD2 4.25Å; F316-F358 AromaticContact CE2-CG 3.7Å; F316-F358 HydrophobicContact CE2-CG 3.7Å; F316-F358 HydrophobicContact CZ-CB 3.52Å; F316-F358 HydrophobicContact CZ-CD2 4.28Å; F316-F358 AromaticContact CZ-CG 3.94Å; F316-F358 HydrophobicContact CZ-CG 3.94Å; V324-F358 HydrophobicContact CG1-CD2 3.66Å; V324-F358 HydrophobicContact CG1-CE2 4.21Å; T354-F358 WeakPolarHBondContact O-CB 3.35Å; T354-F358 PolarHBondContact O-N 3.1Å; G355-F358 WeakPolarHBondContact O-CB 3.35Å; G355-F358 PolarHBondContact O-N 3.24Å; F358-G360 VanDerWaalsContact C-N 3.3Å; F358-G360 PolarHBondContact O-N 3.33Å; F358-C361 VanDerWaalsContact O-CB 3.3Å; F358-C361 WeakPolarHBondContact O-CB 3.18Å; F358-C361 PolarHBondContact O-N 3.16Å; F358-E362 HydrophobicContact CD2-CG 3.94Å; F358-E362 HydrophobicContact CE1-CG 4.37Å; F358-E362 HydrophobicContact CE2-CG 3.38Å; F358-E362 HydrophobicContact CZ-CG 3.63Å; F358-E362 PolarHBondContact O-N 2.92Å
359	L	87.7	Confident	86.8	Confident	0 Å²	0	20.7 Å²	20.7	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-61.9	-40.4	176.6	-66.9	176.1	0	0	0	111.9	E219 V311 F312 G355 G356 I357 C361 F363 C367 W371	E219-L359 HydrophobicContact CG-CD2 4.45Å; E219-L359 VanDerWaalsContact OE2-CD2 3.29Å; E219-L359 WeakPolarHBondContact OE2-CD2 3.3Å; V311-L359 HydrophobicContact CG1-CD2 3.78Å; F312-L359 HydrophobicContact CE1-CD2 4.49Å; F312-L359 HydrophobicContact CE1-CG 4.25Å; F312-L359 HydrophobicContact CZ-CD1 3.94Å; F312-L359 HydrophobicContact CZ-CD2 4.42Å; F312-L359 HydrophobicContact CZ-CG 4.09Å; G355-L359 WeakPolarHBondContact O-CG 3.21Å; G355-L359 PolarHBondContact O-N 3.42Å; G356-L359 PolarHBondContact O-N 3.12Å; I357-L359 PolarHBondContact O-N 3.16Å; L359-C361 PolarHBondContact O-N 3.15Å; L359-F363 HydrophobicContact CD2-CD2 3.9Å; L359-F363 HydrophobicContact CD2-CE2 3.95Å; L359-F363 WeakPolarHBondContact O-CB 3.35Å; L359-F363 PolarHBondContact O-N 2.96Å; L359-C367 HydrophobicContact CB-CB 4.32Å; L359-W371 HydrophobicContact CD1-CB 3.89Å; L359-W371 HydrophobicContact CD1-CD2 3.85Å; L359-W371 HydrophobicContact CD1-CE3 3.61Å; L359-W371 HydrophobicContact CD1-CG 4Å; L359-W371 HydrophobicContact CD1-CZ3 4.33Å
360	G	87	Confident	87.2	Confident	0 Å²	0	22.1 Å²	22.1	0%	0	12%	0.124	C	C	.	.	H	α-helix	trans	-59.8	-32.6	172.5	0	0	0	0	0	113.6	I334 G356 I357 F358 G364	I334-G360 VanDerWaalsContact CD1-C 3.48Å; G356-G360 PolarHBondContact O-N 3.27Å; I357-G360 PolarHBondContact O-N 3.44Å; I357-G360 VanDerWaalsContact O-N 3.16Å; F358-G360 VanDerWaalsContact C-N 3.3Å; F358-G360 PolarHBondContact O-N 3.33Å; G360-G364 WeakPolarHBondContact CA-O 3.34Å; G360-G364 CarbonylContact O-C 3.4Å; G360-G364 VanDerWaalsContact O-C 3.3Å; G360-G364 WeakPolarHBondContact O-CA 3.5Å; G360-G364 PolarHBondContact O-N 3.36Å; G360-G364 VanDerWaalsContact O-N 3.11Å
361	C	84.9	Confident	87.4	Confident	2 Å²	2	21.8 Å²	21.8	1%	0.014	12%	0.122	C	C	.	.	H	α-helix	trans	-79.1	-46.4	-173.5	-76.4	0	0	0	0	111.2	C328 K333 I334 I357 F358 L359	C328-C361 HydrophobicContact CB-CB 3.44Å; C328-C361 VanDerWaalsContact CB-CB 3.44Å; C328-C361 WeakPolarHBondContact CB-SG 3.24Å; C328-C361 WeakPolarHBondContact SG-CA 3.34Å; C328-C361 WeakPolarHBondContact SG-CB 3.45Å; C328-C361 CovalentContact SG-SG 2Å; C328-C361 PolarHBondContact SG-SG 3.24Å; K333-C361 WeakPolarHBondContact CD-O 3.04Å; K333-C361 PolarHBondContact NZ-O 3.24Å; I334-C361 HydrophobicContact CD1-CB 4.17Å; I334-C361 WeakPolarHBondContact CD1-SG 3.26Å; I357-C361 WeakPolarHBondContact O-CB 3.34Å; I357-C361 PolarHBondContact O-N 3.46Å; I357-C361 PolarHBondContact O-SG 2.82Å; F358-C361 VanDerWaalsContact O-CB 3.3Å; F358-C361 WeakPolarHBondContact O-CB 3.18Å; F358-C361 PolarHBondContact O-N 3.16Å; L359-C361 PolarHBondContact O-N 3.15Å
362	E	83.4	Confident	87.5	Confident	103 Å²	103	21.6 Å²	21.6	48%	0.481	12%	0.121	S	C	.	.	H	α-helix	trans	-81.3	-42.3	-176.2	-67.3	-62.5	154.6	0	0	111.8	F358	F358-E362 HydrophobicContact CD2-CG 3.94Å; F358-E362 HydrophobicContact CE1-CG 4.37Å; F358-E362 HydrophobicContact CE2-CG 3.38Å; F358-E362 HydrophobicContact CZ-CG 3.63Å; F358-E362 PolarHBondContact O-N 2.92Å
363	F	84.1	Confident	87.4	Confident	51 Å²	51	25.6 Å²	25.6	22%	0.224	14%	0.141	C	C	.	.	H	α-helix	trans	-112.7	-6.3	-170.6	-50.9	-63.9	0	0	0	114	E219 V222 V223 L359 C367	E219-F363 HydrophobicContact CG-CD2 4.47Å; V222-F363 HydrophobicContact CB-CD1 4.26Å; V222-F363 HydrophobicContact CB-CE1 4.05Å; V222-F363 HydrophobicContact CG1-CD1 3.68Å; V222-F363 HydrophobicContact CG1-CE1 3.54Å; V223-F363 HydrophobicContact CG2-CE1 4.1Å; V223-F363 HydrophobicContact CG2-CE2 3.93Å; V223-F363 HydrophobicContact CG2-CZ 3.27Å; L359-F363 HydrophobicContact CD2-CD2 3.9Å; L359-F363 HydrophobicContact CD2-CE2 3.95Å; L359-F363 WeakPolarHBondContact O-CB 3.35Å; L359-F363 PolarHBondContact O-N 2.96Å; F363-C367 HydrophobicContact CB-CB 3.8Å; F363-C367 WeakPolarHBondContact CB-SG 3.49Å
364	G	85.7	Confident	87.2	Confident	24 Å²	24	25.8 Å²	25.8	25%	0.247	14%	0.144	C	C	.	.			trans	95.8	169.4	178.3	0	0	0	0	0	113.8	G360 A366 C367	G360-G364 WeakPolarHBondContact CA-O 3.34Å; G360-G364 CarbonylContact O-C 3.4Å; G360-G364 VanDerWaalsContact O-C 3.3Å; G360-G364 WeakPolarHBondContact O-CA 3.5Å; G360-G364 PolarHBondContact O-N 3.36Å; G360-G364 VanDerWaalsContact O-N 3.11Å; G364-A366 PolarHBondContact O-N 2.73Å; G364-A366 VanDerWaalsContact O-N 3.08Å; G364-C367 PolarHBondContact O-N 3.22Å; G364-C367 VanDerWaalsContact O-N 3.07Å
365	L	87.4	Confident	87.3	Confident	65 Å²	65	25.9 Å²	25.9	34%	0.34	15%	0.145	S	C	.	.	H	α-helix	trans	-57.9	-28.3	-173	-67.5	173.2	0	0	0	114.3	I334 C367 L368 F369	I334-L365 HydrophobicContact CG1-CD2 4.33Å; L365-C367 VanDerWaalsContact C-N 3.34Å; L365-C367 PolarHBondContact O-N 3.22Å; L365-L368 PolarHBondContact O-N 2.72Å; L365-F369 HydrophobicContact CB-CD2 4.47Å; L365-F369 HydrophobicContact CB-CE2 4.27Å; L365-F369 WeakPolarHBondContact O-CD2 3.44Å; L365-F369 PolarHBondContact O-N 3.03Å
366	A	86.3	Confident	87.3	Confident	65 Å²	65	28.3 Å²	28.3	54%	0.537	16%	0.157	S	C	.	.	H	α-helix	trans	-59.7	-44.3	177.1	0	0	0	0	0	111.7	G364 F369 I370	G364-A366 PolarHBondContact O-N 2.73Å; G364-A366 VanDerWaalsContact O-N 3.08Å; A366-F369 PolarHBondContact O-N 2.95Å; A366-I370 WeakPolarHBondContact O-CB 3.15Å; A366-I370 WeakPolarHBondContact O-CD1 3.46Å; A366-I370 WeakPolarHBondContact O-CG1 3.26Å; A366-I370 PolarHBondContact O-N 3.01Å
367	C	85.1	Confident	87	Confident	9 Å²	9	28.8 Å²	28.8	6%	0.061	16%	0.161	C	C	.	.	H	α-helix	trans	-66.1	-39.6	177.9	-71.7	0	0	0	0	112	L359 F363 G364 L365 F369 I370 W371	L359-C367 HydrophobicContact CB-CB 4.32Å; F363-C367 HydrophobicContact CB-CB 3.8Å; F363-C367 WeakPolarHBondContact CB-SG 3.49Å; G364-C367 PolarHBondContact O-N 3.22Å; G364-C367 VanDerWaalsContact O-N 3.07Å; L365-C367 VanDerWaalsContact C-N 3.34Å; L365-C367 PolarHBondContact O-N 3.22Å; C367-F369 PolarHBondContact O-N 2.86Å; C367-I370 PolarHBondContact O-N 3.15Å; C367-W371 WeakPolarHBondContact O-CB 3.49Å; C367-W371 PolarHBondContact O-N 2.97Å
368	L	89.4	Confident	87	Confident	0 Å²	0	29 Å²	29	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-59.2	-45.4	173.3	-178.2	158.4	0	0	0	111.9	L168 I334 F338 G356 I357 L365 W371 A372	L168-L368 HydrophobicContact CB-CD2 4.23Å; L168-L368 HydrophobicContact CD2-CD2 4.36Å; I334-L368 HydrophobicContact CD1-CD1 4.43Å; F338-L368 HydrophobicContact CE2-CD1 4.29Å; F338-L368 HydrophobicContact CZ-CD1 4.42Å; F338-L368 HydrophobicContact CZ-CD2 4.12Å; G356-L368 WeakPolarHBondContact O-CD1 3.39Å; G356-L368 WeakPolarHBondContact O-CG 3.12Å; I357-L368 HydrophobicContact CD1-CD1 3.92Å; L365-L368 PolarHBondContact O-N 2.72Å; L368-W371 WeakPolarHBondContact O-CB 3.24Å; L368-W371 PolarHBondContact O-N 3.3Å; L368-A372 WeakPolarHBondContact O-CB 3.35Å; L368-A372 PolarHBondContact O-N 3.2Å
369	F	89.4	Confident	87	Confident	66 Å²	66	28.7 Å²	28.7	29%	0.289	16%	0.162	S	C	.	.	H	α-helix	trans	-69.3	-37.3	178.4	-72.2	-55.2	0	0	0	112.3	L169 V171 L365 A366 C367 A372 I373	L169-F369 HydrophobicContact CD2-CD1 4.16Å; V171-F369 HydrophobicContact CG2-CE1 4.4Å; V171-F369 HydrophobicContact CG2-CZ 4.18Å; L365-F369 HydrophobicContact CB-CD2 4.47Å; L365-F369 HydrophobicContact CB-CE2 4.27Å; L365-F369 WeakPolarHBondContact O-CD2 3.44Å; L365-F369 PolarHBondContact O-N 3.03Å; A366-F369 PolarHBondContact O-N 2.95Å; C367-F369 PolarHBondContact O-N 2.86Å; F369-A372 PolarHBondContact O-N 2.69Å; F369-I373 VanDerWaalsContact O-CG1 3.25Å; F369-I373 WeakPolarHBondContact O-CG1 3.21Å; F369-I373 PolarHBondContact O-N 2.91Å
370	I	85.8	Confident	86.8	Confident	58 Å²	58	29.7 Å²	29.7	30%	0.297	17%	0.166	S	C	.	.	H	α-helix	trans	-60.5	-45.4	173.3	-77.1	167.4	0	0	0	110.9	T215 A366 C367 A372 I373 G374	T215-I370 HydrophobicContact CG2-CB 4.44Å; T215-I370 HydrophobicContact CG2-CD1 4.38Å; T215-I370 HydrophobicContact CG2-CG1 4.49Å; T215-I370 HydrophobicContact CG2-CG2 3.19Å; A366-I370 WeakPolarHBondContact O-CB 3.15Å; A366-I370 WeakPolarHBondContact O-CD1 3.46Å; A366-I370 WeakPolarHBondContact O-CG1 3.26Å; A366-I370 PolarHBondContact O-N 3.01Å; C367-I370 PolarHBondContact O-N 3.15Å; I370-A372 VanDerWaalsContact C-N 3.35Å; I370-A372 PolarHBondContact O-N 2.93Å; I370-I373 PolarHBondContact O-N 3.29Å; I370-G374 PolarHBondContact O-N 3.42Å
371	W	88.8	Confident	86.6	Confident	2 Å²	2	29.9 Å²	29.9	1%	0.008	17%	0.168	C	C	.	.	H	α-helix	trans	-55.7	-49.6	172.4	172	-101.3	0	0	0	111.1	I84 L88 F216 F312 L352 L359 C367 L368 I373 G374 L375	I84-W371 HydrophobicContact CG2-CH2 3.38Å; I84-W371 HydrophobicContact CG2-CZ2 4.16Å; I84-W371 HydrophobicContact CG2-CZ3 3.99Å; L88-W371 HydrophobicContact CD1-CH2 4.18Å; L88-W371 HydrophobicContact CD1-CZ2 4.19Å; F216-W371 AromaticContact CE1-CE3 3.32Å; F216-W371 HydrophobicContact CE1-CE3 3.32Å; F216-W371 AromaticContact CE1-CZ3 3.35Å; F216-W371 HydrophobicContact CE1-CZ3 3.35Å; F216-W371 AromaticContact CZ-CE3 3.39Å; F216-W371 HydrophobicContact CZ-CE3 3.39Å; F216-W371 AromaticContact CZ-CZ3 3.34Å; F216-W371 HydrophobicContact CZ-CZ3 3.34Å; F312-W371 AromaticContact CE2-CH2 3.7Å; F312-W371 HydrophobicContact CE2-CH2 3.7Å; F312-W371 AromaticContact CE2-CZ3 3.77Å; F312-W371 HydrophobicContact CE2-CZ3 3.77Å; F312-W371 HydrophobicContact CZ-CE3 4.46Å; F312-W371 AromaticContact CZ-CH2 3.82Å; F312-W371 HydrophobicContact CZ-CH2 3.82Å; F312-W371 HydrophobicContact CZ-CZ2 4.32Å; F312-W371 AromaticContact CZ-CZ3 3.9Å; F312-W371 HydrophobicContact CZ-CZ3 3.9Å; L352-W371 HydrophobicContact CD2-CH2 4.34Å; L352-W371 HydrophobicContact CD2-CZ2 3.84Å; L352-W371 PolarHBondContact O-NE1 3.47Å; L359-W371 HydrophobicContact CD1-CB 3.89Å; L359-W371 HydrophobicContact CD1-CD2 3.85Å; L359-W371 HydrophobicContact CD1-CE3 3.61Å; L359-W371 HydrophobicContact CD1-CG 4Å; L359-W371 HydrophobicContact CD1-CZ3 4.33Å; C367-W371 WeakPolarHBondContact O-CB 3.49Å; C367-W371 PolarHBondContact O-N 2.97Å; L368-W371 WeakPolarHBondContact O-CB 3.24Å; L368-W371 PolarHBondContact O-N 3.3Å; W371-I373 PolarHBondContact O-N 3.02Å; W371-G374 PolarHBondContact O-N 3.21Å; W371-G374 VanDerWaalsContact O-N 3.14Å; W371-L375 HydrophobicContact CD2-CD1 4.45Å; W371-L375 HydrophobicContact CD2-CG 4.38Å; W371-L375 HydrophobicContact CZ2-CD1 4.17Å; W371-L375 HydrophobicContact CZ2-CD2 4.17Å; W371-L375 HydrophobicContact CZ2-CG 4.37Å; W371-L375 VanDerWaalsContact NE1-CD1 3.25Å; W371-L375 WeakPolarHBondContact O-CG 3.38Å; W371-L375 PolarHBondContact O-N 3.31Å
372	A	90.8	Very high	86.6	Confident	0 Å²	0	29.9 Å²	29.9	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-63.9	-38.8	179.8	0	0	0	0	0	112.5	A165 L168 L169 L368 F369 I370 L375 L376	A165-A372 VanDerWaalsContact CB-O 3.25Å; A165-A372 WeakPolarHBondContact CB-O 3.21Å; L168-A372 HydrophobicContact CB-CB 3.65Å; L168-A372 HydrophobicContact CD1-CB 4.24Å; L169-A372 HydrophobicContact CD2-CB 3.96Å; L169-A372 HydrophobicContact CG-CB 3.78Å; L368-A372 WeakPolarHBondContact O-CB 3.35Å; L368-A372 PolarHBondContact O-N 3.2Å; F369-A372 PolarHBondContact O-N 2.69Å; I370-A372 VanDerWaalsContact C-N 3.35Å; I370-A372 PolarHBondContact O-N 2.93Å; A372-L375 PolarHBondContact O-N 3.4Å; A372-L376 WeakPolarHBondContact O-CB 3.27Å; A372-L376 PolarHBondContact O-N 3.28Å
373	I	87.6	Confident	86.8	Confident	84 Å²	84	25.2 Å²	25.2	43%	0.431	15%	0.146	S	C	.	.	H	α-helix	trans	-64.1	-42.5	172.8	-68.1	167.5	0	0	0	110.6	L169 F369 I370 W371 L376 A377	L169-I373 HydrophobicContact CD2-CG1 3.92Å; F369-I373 VanDerWaalsContact O-CG1 3.25Å; F369-I373 WeakPolarHBondContact O-CG1 3.21Å; F369-I373 PolarHBondContact O-N 2.91Å; I370-I373 PolarHBondContact O-N 3.29Å; W371-I373 PolarHBondContact O-N 3.02Å; I373-L376 PolarHBondContact O-N 2.81Å; I373-A377 VanDerWaalsContact O-CB 3.24Å; I373-A377 WeakPolarHBondContact O-CB 3.11Å; I373-A377 PolarHBondContact O-N 2.94Å
374	G	85.6	Confident	86.7	Confident	7 Å²	7	22.9 Å²	22.9	7%	0.072	14%	0.136	C	C	.	.	H	α-helix	trans	-61.3	-44.8	176.5	0	0	0	0	0	112.3	I370 W371 A377 A378	I370-G374 PolarHBondContact O-N 3.42Å; W371-G374 PolarHBondContact O-N 3.21Å; W371-G374 VanDerWaalsContact O-N 3.14Å; G374-A377 WeakPolarHBondContact O-CB 3.42Å; G374-A377 PolarHBondContact O-N 3.41Å; G374-A378 WeakPolarHBondContact O-CB 3.3Å; G374-A378 PolarHBondContact O-N 2.85Å
375	L	89.3	Confident	86.7	Confident	2 Å²	2	21.8 Å²	21.8	1%	0.01	12%	0.124	C	C	.	.	H	α-helix	trans	-64.5	-41.7	175	-71.7	-174.9	0	0	0	112.5	I84 I164 A165 L352 W371 A372 A378 G379	I84-L375 HydrophobicContact CD1-CD2 4.2Å; I84-L375 HydrophobicContact CG2-CD2 4.3Å; I164-L375 HydrophobicContact CG2-CD1 4.16Å; A165-L375 HydrophobicContact CB-CB 3.9Å; L352-L375 HydrophobicContact CB-CD1 4.05Å; L352-L375 HydrophobicContact CD1-CD2 4.31Å; L352-L375 HydrophobicContact CD2-CD2 3.93Å; W371-L375 HydrophobicContact CD2-CD1 4.45Å; W371-L375 HydrophobicContact CD2-CG 4.38Å; W371-L375 HydrophobicContact CZ2-CD1 4.17Å; W371-L375 HydrophobicContact CZ2-CD2 4.17Å; W371-L375 HydrophobicContact CZ2-CG 4.37Å; W371-L375 VanDerWaalsContact NE1-CD1 3.25Å; W371-L375 WeakPolarHBondContact O-CG 3.38Å; W371-L375 PolarHBondContact O-N 3.31Å; A372-L375 PolarHBondContact O-N 3.4Å; L375-A378 PolarHBondContact O-N 3.32Å; L375-G379 PolarHBondContact O-N 2.92Å
376	L	89.1	Confident	86.8	Confident	51 Å²	51	19.2 Å²	19.2	27%	0.267	11%	0.113	S	C	.	.	H	α-helix	trans	-59.3	-51	174.5	-175.5	61.2	0	0	0	109.6	T162 A165 L169 A372 I373 A378 G379 Q380	T162-L376 HydrophobicContact CG2-CD1 3.77Å; A165-L376 HydrophobicContact CB-CB 3.85Å; L169-L376 HydrophobicContact CD1-CD2 3.91Å; A372-L376 WeakPolarHBondContact O-CB 3.27Å; A372-L376 PolarHBondContact O-N 3.28Å; I373-L376 PolarHBondContact O-N 2.81Å; L376-A378 PolarHBondContact O-N 3.27Å; L376-G379 WeakPolarHBondContact O-CA 3.41Å; L376-G379 PolarHBondContact O-N 3.1Å; L376-Q380 VanDerWaalsContact O-CG 3.27Å; L376-Q380 WeakPolarHBondContact O-CG 3.43Å; L376-Q380 PolarHBondContact O-N 3.32Å
377	A	83.9	Confident	86.8	Confident	10 Å²	10	16.3 Å²	16.3	8%	0.083	9%	0.089	C	C	.	.	H	α-helix	trans	-58.5	-45.7	178.5	0	0	0	0	0	113.2	L208 I373 G374 G379 S381	L208-A377 HydrophobicContact CB-CB 4.27Å; L208-A377 HydrophobicContact CD1-CB 3.82Å; L208-A377 HydrophobicContact CD2-CB 3.65Å; L208-A377 HydrophobicContact CG-CB 4.09Å; I373-A377 VanDerWaalsContact O-CB 3.24Å; I373-A377 WeakPolarHBondContact O-CB 3.11Å; I373-A377 PolarHBondContact O-N 2.94Å; G374-A377 WeakPolarHBondContact O-CB 3.42Å; G374-A377 PolarHBondContact O-N 3.41Å; A377-G379 VanDerWaalsContact C-N 3.32Å; A377-S381 WeakPolarHBondContact O-CB 3.25Å; A377-S381 PolarHBondContact O-N 2.95Å; A377-S381 PolarHBondContact O-OG 3.07Å
378	A	87	Confident	86.8	Confident	4 Å²	4	16 Å²	16	3%	0.033	9%	0.087	C	C	.	.	H	α-helix	trans	-61.3	-42.9	175.2	0	0	0	0	0	111.1	L79 P81 I84 M212 G374 L375 L376 S381 S382	L79-A378 WeakPolarHBondContact O-CB 3.4Å; P81-A378 HydrophobicContact CG-CB 4.3Å; I84-A378 HydrophobicContact CD1-CB 4.23Å; M212-A378 HydrophobicContact CE-CB 4.48Å; G374-A378 WeakPolarHBondContact O-CB 3.3Å; G374-A378 PolarHBondContact O-N 2.85Å; L375-A378 PolarHBondContact O-N 3.32Å; L376-A378 PolarHBondContact O-N 3.27Å; A378-S381 PolarHBondContact O-N 3.38Å; A378-S382 WeakPolarHBondContact O-CB 3.23Å; A378-S382 PolarHBondContact O-N 3.01Å
379	G	88.2	Confident	86.9	Confident	0 Å²	0	16 Å²	16	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-55.8	-60	173.9	0	0	0	0	0	112.3	E158 L375 L376 A377 S381 S382 T383	E158-G379 VanDerWaalsContact CG-C 3.44Å; E158-G379 WeakPolarHBondContact CG-O 3.35Å; L375-G379 PolarHBondContact O-N 2.92Å; L376-G379 WeakPolarHBondContact O-CA 3.41Å; L376-G379 PolarHBondContact O-N 3.1Å; A377-G379 VanDerWaalsContact C-N 3.32Å; G379-S381 PolarHBondContact O-N 3.44Å; G379-S381 VanDerWaalsContact O-N 3.12Å; G379-S382 PolarHBondContact O-N 3.12Å; G379-S382 VanDerWaalsContact O-N 3.07Å; G379-T383 PolarHBondContact O-N 2.89Å; G379-T383 VanDerWaalsContact O-N 3.16Å; G379-T383 PolarHBondContact O-OG1 3.27Å
380	Q	84.8	Confident	87	Confident	21 Å²	21	12.9 Å²	12.9	10%	0.098	7%	0.073	C	C	.	.	H	α-helix	trans	-50.2	-43	177.3	-65.3	-56.5	-57.6	0	0	113.3	D186 L376 T383 M384	D186-Q380 PolarHBondContact OD1-NE2 3.21Å; D186-Q380 PolarHBondContact OD1-OE1 2.97Å; D186-Q380 PolarHBondContact OD2-NE2 3.21Å; L376-Q380 VanDerWaalsContact O-CG 3.27Å; L376-Q380 WeakPolarHBondContact O-CG 3.43Å; L376-Q380 PolarHBondContact O-N 3.32Å; Q380-T383 PolarHBondContact O-OG1 3.18Å; Q380-M384 VanDerWaalsContact O-CG 3.27Å; Q380-M384 WeakPolarHBondContact O-CG 3.32Å; Q380-M384 PolarHBondContact O-N 2.8Å
381	S	82.4	Confident	87.2	Confident	4 Å²	4	10.5 Å²	10.5	3%	0.028	6%	0.061	C	C	.	.	H	α-helix	trans	-70.2	-39.1	-175	-54.8	0	0	0	0	111	F205 A377 A378 G379 M384 T385	F205-S381 VanDerWaalsContact CD1-OG 3.23Å; F205-S381 WeakPolarHBondContact CD1-OG 3.38Å; F205-S381 VanDerWaalsContact CE1-CB 3.43Å; F205-S381 WeakPolarHBondContact CE1-OG 2.93Å; A377-S381 WeakPolarHBondContact O-CB 3.25Å; A377-S381 PolarHBondContact O-N 2.95Å; A377-S381 PolarHBondContact O-OG 3.07Å; A378-S381 PolarHBondContact O-N 3.38Å; G379-S381 PolarHBondContact O-N 3.44Å; G379-S381 VanDerWaalsContact O-N 3.12Å; S381-M384 PolarHBondContact O-N 3Å; S381-T385 PolarHBondContact O-N 3.18Å; S381-T385 PolarHBondContact O-OG1 2.95Å
382	S	85.5	Confident	87.4	Confident	1 Å²	1	11 Å²	11	1%	0.007	6%	0.063	C	C	.	.	H	α-helix	trans	-67.8	-33.9	177.6	-158	0	0	0	0	112.8	A378 G379 M384 T385 G386	A378-S382 WeakPolarHBondContact O-CB 3.23Å; A378-S382 PolarHBondContact O-N 3.01Å; G379-S382 PolarHBondContact O-N 3.12Å; G379-S382 VanDerWaalsContact O-N 3.07Å; S382-M384 VanDerWaalsContact C-N 3.28Å; S382-M384 PolarHBondContact O-N 2.71Å; S382-T385 WeakPolarHBondContact CA-OG1 3.14Å; S382-T385 PolarHBondContact O-N 3.37Å; S382-T385 PolarHBondContact O-OG1 3.06Å; S382-G386 PolarHBondContact O-N 3Å
383	T	85.7	Confident	87.4	Confident	6 Å²	6	11 Å²	11	4%	0.037	6%	0.063	C	C	.	.	H	α-helix	trans	-66.9	-34.4	176.2	24.3	0	0	0	0	110.9	E158 F190 G379 Q380 T387	E158-T383 VanDerWaalsContact CD-N 3.3Å; E158-T383 WeakPolarHBondContact OE1-CB 3.34Å; E158-T383 PolarHBondContact OE1-OG1 2.66Å; E158-T383 WeakPolarHBondContact OE2-CA 3.49Å; E158-T383 WeakPolarHBondContact OE2-CB 3.37Å; E158-T383 PolarHBondContact OE2-N 2.64Å; E158-T383 PolarHBondContact OE2-OG1 3.12Å; F190-T383 HydrophobicContact CB-CG2 4.37Å; G379-T383 PolarHBondContact O-N 2.89Å; G379-T383 VanDerWaalsContact O-N 3.16Å; G379-T383 PolarHBondContact O-OG1 3.27Å; Q380-T383 PolarHBondContact O-OG1 3.18Å; T383-T387 VanDerWaalsContact O-CB 3.25Å; T383-T387 WeakPolarHBondContact O-CB 3.31Å; T383-T387 PolarHBondContact O-N 3.16Å; T383-T387 PolarHBondContact O-OG1 3.33Å
384	M	82.7	Confident	87.6	Confident	1 Å²	1	7.7 Å²	7.7	1%	0.005	5%	0.046	C	C	.	.	H	α-helix	trans	-65.2	-48.6	175	-49.2	-145.5	-168	0	0	111.5	F190 L193 L201 F205 Q380 S381 S382 T387 Y388	F190-M384 HydrophobicContact CD2-CB 3.91Å; F190-M384 HydrophobicContact CD2-CE 4.41Å; F190-M384 HydrophobicContact CD2-CG 3.46Å; F190-M384 VanDerWaalsContact CD2-CG 3.46Å; F190-M384 HydrophobicContact CD2-SD 3.68Å; F190-M384 HydrophobicContact CE2-CB 3.9Å; F190-M384 HydrophobicContact CE2-CG 3.97Å; F190-M384 HydrophobicContact CE2-SD 4.12Å; F190-M384 HydrophobicContact CG-CG 4.49Å; L193-M384 HydrophobicContact CB-CE 3.91Å; L193-M384 HydrophobicContact CD1-CE 3.35Å; L193-M384 HydrophobicContact CG-CE 4.24Å; L201-M384 HydrophobicContact CD1-SD 3.57Å; L201-M384 VanDerWaalsContact CD1-SD 3.57Å; L201-M384 HydrophobicContact CG-SD 4.13Å; F205-M384 HydrophobicContact CE1-CE 4.21Å; F205-M384 HydrophobicContact CE1-SD 4.24Å; F205-M384 HydrophobicContact CE2-SD 4.17Å; F205-M384 HydrophobicContact CZ-CB 3.96Å; F205-M384 HydrophobicContact CZ-CE 3.96Å; F205-M384 HydrophobicContact CZ-CG 3.74Å; F205-M384 HydrophobicContact CZ-SD 3.41Å; F205-M384 WeakPolarHBondContact CZ-SD 3.31Å; Q380-M384 VanDerWaalsContact O-CG 3.27Å; Q380-M384 WeakPolarHBondContact O-CG 3.32Å; Q380-M384 PolarHBondContact O-N 2.8Å; S381-M384 PolarHBondContact O-N 3Å; S382-M384 VanDerWaalsContact C-N 3.28Å; S382-M384 PolarHBondContact O-N 2.71Å; M384-T387 PolarHBondContact O-N 3.12Å; M384-Y388 HydrophobicContact CB-CE2 4.46Å; M384-Y388 WeakPolarHBondContact O-CD2 3.33Å; M384-Y388 PolarHBondContact O-N 3Å
385	T	86.8	Confident	87.9	Confident	1 Å²	1	8.2 Å²	8.2	1%	0.006	5%	0.046	C	C	.	.	H	α-helix	trans	-65.9	-42.7	-179	56.6	0	0	0	0	111.1	L73 I76 L265 S381 S382 T387 Y388 S389	L73-T385 WeakPolarHBondContact O-CG2 3.15Å; I76-T385 HydrophobicContact CB-CG2 4.28Å; I76-T385 HydrophobicContact CD1-CG2 4.36Å; I76-T385 HydrophobicContact CG2-CG2 4.22Å; L265-T385 HydrophobicContact CD2-CG2 3.86Å; S381-T385 PolarHBondContact O-N 3.18Å; S381-T385 PolarHBondContact O-OG1 2.95Å; S382-T385 WeakPolarHBondContact CA-OG1 3.14Å; S382-T385 PolarHBondContact O-N 3.37Å; S382-T385 PolarHBondContact O-OG1 3.06Å; T385-T387 VanDerWaalsContact C-N 3.35Å; T385-T387 PolarHBondContact O-N 2.87Å; T385-Y388 PolarHBondContact O-N 2.95Å; T385-S389 VanDerWaalsContact O-CB 3.26Å; T385-S389 WeakPolarHBondContact O-CB 3.41Å; T385-S389 PolarHBondContact O-N 2.68Å; T385-S389 PolarHBondContact O-OG 2.9Å
386	G	87.9	Confident	88	Confident	11 Å²	11	8.1 Å²	8.1	11%	0.113	5%	0.046	C	C	.	.	H	α-helix	trans	-59.6	-42.8	174.1	0	0	0	0	0	112.4	S382 G390	S382-G386 PolarHBondContact O-N 3Å; G386-G390 PolarHBondContact O-N 2.82Å
387	T	86.9	Confident	88.2	Confident	4 Å²	4	5.7 Å²	5.7	3%	0.025	3%	0.033	C	C	.	.	H	α-helix	trans	-61.2	-50.6	176.5	-61.3	0	0	0	0	112.3	F190 T383 M384 T385 G390 Q391 V408	F190-T387 HydrophobicContact CE1-CG2 3.63Å; F190-T387 HydrophobicContact CZ-CG2 3.64Å; T383-T387 VanDerWaalsContact O-CB 3.25Å; T383-T387 WeakPolarHBondContact O-CB 3.31Å; T383-T387 PolarHBondContact O-N 3.16Å; T383-T387 PolarHBondContact O-OG1 3.33Å; M384-T387 PolarHBondContact O-N 3.12Å; T385-T387 VanDerWaalsContact C-N 3.35Å; T385-T387 PolarHBondContact O-N 2.87Å; T387-G390 PolarHBondContact O-N 3.13Å; T387-Q391 WeakPolarHBondContact O-CB 3.4Å; T387-Q391 PolarHBondContact O-N 3.23Å; T387-V408 HydrophobicContact CG2-CG2 3.19Å; T387-V408 WeakPolarHBondContact OG1-CG2 3.44Å
388	Y	86.1	Confident	88.5	Confident	4 Å²	4	7.5 Å²	7.5	2%	0.016	4%	0.041	C	C	.	.	H	α-helix	trans	-66.4	-45.7	-179.8	-70.1	-49.9	0	0	0	111.6	F44 F190 D194 L201 M384 T385 G390 Q391 F392	F44-Y388 HydrophobicContact CE1-CE1 4.07Å; F44-Y388 AromaticContact CZ-CD1 3.76Å; F44-Y388 HydrophobicContact CZ-CD1 3.76Å; F44-Y388 AromaticContact CZ-CE1 3.62Å; F44-Y388 HydrophobicContact CZ-CE1 3.62Å; F44-Y388 HydrophobicContact CZ-CG 4.4Å; F190-Y388 HydrophobicContact CE2-CE2 4.38Å; F190-Y388 HydrophobicContact CZ-CE1 4.47Å; D194-Y388 PolarHBondContact OD1-OH 2.93Å; L201-Y388 HydrophobicContact CD1-CE2 4.48Å; M384-Y388 HydrophobicContact CB-CE2 4.46Å; M384-Y388 WeakPolarHBondContact O-CD2 3.33Å; M384-Y388 PolarHBondContact O-N 3Å; T385-Y388 PolarHBondContact O-N 2.95Å; Y388-G390 PolarHBondContact O-N 3.23Å; Y388-Q391 PolarHBondContact O-N 2.91Å; Y388-F392 WeakPolarHBondContact O-CD2 3.34Å; Y388-F392 WeakPolarHBondContact O-CG 3.41Å; Y388-F392 PolarHBondContact O-N 3.02Å
389	S	91.1	Very high	88.6	Confident	0 Å²	0	10.9 Å²	10.9	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-53.2	-47.2	176.7	-57.9	0	0	0	0	110.7	H261 L265 T385 A393	H261-S389 PolarHBondContact CD2-OG 3.4Å; L265-S389 WeakPolarHBondContact CB-OG 3.47Å; T385-S389 VanDerWaalsContact O-CB 3.26Å; T385-S389 WeakPolarHBondContact O-CB 3.41Å; T385-S389 PolarHBondContact O-N 2.68Å; T385-S389 PolarHBondContact O-OG 2.9Å; S389-A393 WeakPolarHBondContact O-CB 3.48Å; S389-A393 PolarHBondContact O-N 3.31Å
390	G	91.6	Very high	88.7	Confident	0 Å²	0	14.3 Å²	14.3	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-62	-50.4	175.3	0	0	0	0	0	112.4	G386 T387 Y388 F392 A393 M394 R407	G386-G390 PolarHBondContact O-N 2.82Å; T387-G390 PolarHBondContact O-N 3.13Å; Y388-G390 PolarHBondContact O-N 3.23Å; G390-F392 PolarHBondContact O-N 3.04Å; G390-A393 CarbonylContact O-C 3.58Å; G390-A393 WeakPolarHBondContact O-CA 3.49Å; G390-A393 WeakPolarHBondContact O-CB 3.44Å; G390-A393 PolarHBondContact O-N 3.12Å; G390-M394 PolarHBondContact O-N 3.22Å; G390-R407 PolarHBondContact O-NH1 2.93Å; G390-R407 PolarHBondContact O-NH2 3.32Å
391	Q	90.2	Very high	88.6	Confident	8 Å²	8	18.8 Å²	18.8	4%	0.037	10%	0.096	C	C	.	.	H	α-helix	trans	-54.7	-45	-177.9	-174.6	176.6	4.3	0	0	110.4	T387 Y388 M394 E395	T387-Q391 WeakPolarHBondContact O-CB 3.4Å; T387-Q391 PolarHBondContact O-N 3.23Å; Y388-Q391 PolarHBondContact O-N 2.91Å; Q391-M394 PolarHBondContact O-N 3.4Å; Q391-E395 HydrophobicContact CG-CG 4.36Å; Q391-E395 WeakPolarHBondContact CG-OE1 3.24Å; Q391-E395 PolarHBondContact NE2-OE1 3.4Å; Q391-E395 WeakPolarHBondContact O-CB 3.34Å; Q391-E395 WeakPolarHBondContact O-CG 3.47Å; Q391-E395 PolarHBondContact O-N 3.24Å
392	F	91.3	Very high	88.6	Confident	13 Å²	13	23 Å²	23	6%	0.057	11%	0.111	C	C	.	.	H	α-helix	trans	-63.9	-38.8	173.7	-60.2	-50.4	0	0	0	112.9	F44 H126 L265 A268 Y388 G390 G396	F44-F392 HydrophobicContact CD2-CZ 4.44Å; F44-F392 HydrophobicContact CE2-CE1 4.07Å; F44-F392 AromaticContact CE2-CZ 3.57Å; F44-F392 HydrophobicContact CE2-CZ 3.57Å; F44-F392 HydrophobicContact CZ-CZ 4.14Å; H126-F392 PolarHBondContact CE1-O 3.14Å; L265-F392 HydrophobicContact CD1-CD2 4.41Å; L265-F392 HydrophobicContact CD1-CE2 4.16Å; A268-F392 HydrophobicContact CB-CB 4.24Å; A268-F392 HydrophobicContact CB-CD1 3.72Å; A268-F392 HydrophobicContact CB-CD2 3.33Å; A268-F392 HydrophobicContact CB-CE1 3.79Å; A268-F392 HydrophobicContact CB-CE2 3.41Å; A268-F392 VanDerWaalsContact CB-CE2 3.41Å; A268-F392 HydrophobicContact CB-CG 3.49Å; A268-F392 VanDerWaalsContact CB-CG 3.49Å; A268-F392 HydrophobicContact CB-CZ 3.63Å; Y388-F392 WeakPolarHBondContact O-CD2 3.34Å; Y388-F392 WeakPolarHBondContact O-CG 3.41Å; Y388-F392 PolarHBondContact O-N 3.02Å; G390-F392 PolarHBondContact O-N 3.04Å; F392-G396 WeakPolarHBondContact O-CA 3.33Å; F392-G396 PolarHBondContact O-N 3.23Å
393	A	92.6	Very high	88.6	Confident	0 Å²	0	29 Å²	29	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-61.7	-47.6	174.9	0	0	0	0	0	111.4	V147 S389 G390 G396 F397	V147-A393 HydrophobicContact CG1-CB 3.92Å; S389-A393 WeakPolarHBondContact O-CB 3.48Å; S389-A393 PolarHBondContact O-N 3.31Å; G390-A393 CarbonylContact O-C 3.58Å; G390-A393 WeakPolarHBondContact O-CA 3.49Å; G390-A393 WeakPolarHBondContact O-CB 3.44Å; G390-A393 PolarHBondContact O-N 3.12Å; A393-G396 PolarHBondContact O-N 3.49Å; A393-F397 HydrophobicContact CB-CD2 4.15Å; A393-F397 HydrophobicContact CB-CE2 4.45Å; A393-F397 VanDerWaalsContact O-CB 3.25Å; A393-F397 WeakPolarHBondContact O-CB 3.49Å; A393-F397 VanDerWaalsContact O-CD2 3.22Å; A393-F397 WeakPolarHBondContact O-CD2 3.45Å; A393-F397 PolarHBondContact O-N 3.15Å
394	M	91.6	Very high	88.3	Confident	13 Å²	13	30.2 Å²	30.2	6%	0.064	14%	0.141	C	C	.	.	H	α-helix	trans	-70.8	-44.5	-177.7	-176	179	-165	0	0	112.9	G390 Q391 G396 L398 N399 L400 W402 R407	G390-M394 PolarHBondContact O-N 3.22Å; Q391-M394 PolarHBondContact O-N 3.4Å; M394-G396 VanDerWaalsContact C-N 3.33Å; M394-L398 WeakPolarHBondContact O-CA 3.41Å; M394-L398 WeakPolarHBondContact O-CB 3.3Å; M394-L398 PolarHBondContact O-N 3.13Å; M394-N399 PolarHBondContact O-N 2.91Å; M394-L400 HydrophobicContact CE-CB 4.24Å; M394-L400 HydrophobicContact CE-CD2 3.28Å; M394-L400 HydrophobicContact CE-CG 3.72Å; M394-L400 HydrophobicContact CG-CB 4.2Å; M394-W402 HydrophobicContact CE-CB 4.1Å; M394-W402 HydrophobicContact CE-CD2 3.24Å; M394-W402 VanDerWaalsContact CE-CE2 3.4Å; M394-W402 HydrophobicContact CE-CE3 3.69Å; M394-W402 HydrophobicContact CE-CG 3.4Å; M394-W402 HydrophobicContact CE-CH2 4.36Å; M394-W402 HydrophobicContact CE-CZ2 4.01Å; M394-W402 HydrophobicContact CE-CZ3 4.19Å; M394-W402 HydrophobicContact SD-CB 4.05Å; M394-W402 HydrophobicContact SD-CD2 4.1Å; M394-W402 HydrophobicContact SD-CE3 4.25Å; M394-W402 HydrophobicContact SD-CG 4Å; M394-R407 PolarHBondContact SD-NH1 2.97Å; M394-R407 VanDerWaalsContact SD-NH1 3.38Å
395	E	91.1	Very high	88.3	Confident	18 Å²	18	36 Å²	36	8%	0.084	16%	0.163	C	C	.	.	H	α-helix	trans	-67	-36.6	175.1	-70.6	-176.6	-166.2	0	0	111.4	Q391 N399	Q391-E395 HydrophobicContact CG-CG 4.36Å; Q391-E395 WeakPolarHBondContact CG-OE1 3.24Å; Q391-E395 PolarHBondContact NE2-OE1 3.4Å; Q391-E395 WeakPolarHBondContact O-CB 3.34Å; Q391-E395 WeakPolarHBondContact O-CG 3.47Å; Q391-E395 PolarHBondContact O-N 3.24Å; E395-N399 WeakPolarHBondContact O-CA 3.32Å; E395-N399 PolarHBondContact O-N 3.34Å
396	G	91.1	Very high	88.3	Confident	0 Å²	0	39.2 Å²	39.2	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-69.7	-64.4	176.8	0	0	0	0	0	112.1	A128 Y132 F392 A393 M394	A128-G396 CarbonylContact O-C 3.6Å; Y132-G396 WeakPolarHBondContact CB-O 3.41Å; Y132-G396 WeakPolarHBondContact CD2-O 3.48Å; F392-G396 WeakPolarHBondContact O-CA 3.33Å; F392-G396 PolarHBondContact O-N 3.23Å; A393-G396 PolarHBondContact O-N 3.49Å; M394-G396 VanDerWaalsContact C-N 3.33Å
397	F	93.2	Very high	88.3	Confident	0 Å²	0	39.1 Å²	39.1	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-74	-32.5	-172.6	-73.1	-78	0	0	0	114.6	A128 C131 Y132 R140 L143 W144 V147 Y264 A393	A128-F397 HydrophobicContact CB-CD2 3.61Å; A128-F397 HydrophobicContact CB-CE2 3.66Å; A128-F397 HydrophobicContact CB-CG 4.24Å; A128-F397 HydrophobicContact CB-CZ 4.37Å; C131-F397 HydrophobicContact CB-CD1 3.82Å; C131-F397 HydrophobicContact CB-CE1 3.3Å; C131-F397 HydrophobicContact CB-CZ 3.98Å; Y132-F397 VanDerWaalsContact CD2-O 3.27Å; Y132-F397 WeakPolarHBondContact CD2-O 3.33Å; R140-F397 WeakPolarHBondContact CD-O 3.41Å; R140-F397 HydrophobicContact CG-CB 4.33Å; R140-F397 HydrophobicContact CG-CD1 3.65Å; R140-F397 HydrophobicContact CG-CG 4.5Å; R140-F397 PolarHBondContact NE-O 3.07Å; L143-F397 HydrophobicContact CB-CD1 4.47Å; L143-F397 HydrophobicContact CB-CE1 3.7Å; L143-F397 HydrophobicContact CB-CZ 4.13Å; L143-F397 HydrophobicContact CD1-CE1 4.28Å; W144-F397 HydrophobicContact CB-CB 3.64Å; W144-F397 HydrophobicContact CB-CD1 4.27Å; W144-F397 HydrophobicContact CB-CD2 4.07Å; W144-F397 HydrophobicContact CB-CG 3.79Å; W144-F397 HydrophobicContact CG-CB 3.99Å; W144-F397 HydrophobicContact CG-CG 4.44Å; V147-F397 HydrophobicContact CG2-CE2 4.16Å; V147-F397 HydrophobicContact CG2-CZ 4.39Å; Y264-F397 HydrophobicContact CD1-CE2 4.14Å; Y264-F397 AromaticContact CE1-CE2 3.54Å; Y264-F397 HydrophobicContact CE1-CE2 3.54Å; Y264-F397 AromaticContact CE1-CZ 3.59Å; Y264-F397 HydrophobicContact CE1-CZ 3.59Å; Y264-F397 AromaticContact CZ-CZ 3.95Å; A393-F397 HydrophobicContact CB-CD2 4.15Å; A393-F397 HydrophobicContact CB-CE2 4.45Å; A393-F397 VanDerWaalsContact O-CB 3.25Å; A393-F397 WeakPolarHBondContact O-CB 3.49Å; A393-F397 VanDerWaalsContact O-CD2 3.22Å; A393-F397 WeakPolarHBondContact O-CD2 3.45Å; A393-F397 PolarHBondContact O-N 3.15Å
398	L	91.3	Very high	88.2	Confident	48 Å²	48	39 Å²	39	25%	0.251	17%	0.174	S	C	.	.	H	α-helix	trans	-110.1	-13.8	-177.2	-58.7	-177.1	0	0	0	113.4	I141 W144 M394 L400	I141-L398 HydrophobicContact CG1-CD2 4.23Å; W144-L398 HydrophobicContact CD2-CD1 3.67Å; W144-L398 HydrophobicContact CD2-CD2 4.23Å; W144-L398 HydrophobicContact CD2-CG 3.96Å; W144-L398 VanDerWaalsContact CE2-CD1 3.46Å; W144-L398 HydrophobicContact CE3-CD1 3.96Å; W144-L398 HydrophobicContact CE3-CD2 4.31Å; W144-L398 HydrophobicContact CE3-CG 4.43Å; W144-L398 HydrophobicContact CG-CD1 4.33Å; W144-L398 HydrophobicContact CG-CD2 4.4Å; W144-L398 HydrophobicContact CG-CG 4.12Å; W144-L398 HydrophobicContact CH2-CD1 3.86Å; W144-L398 HydrophobicContact CZ2-CD1 3.57Å; W144-L398 HydrophobicContact CZ3-CD1 4.04Å; M394-L398 WeakPolarHBondContact O-CA 3.41Å; M394-L398 WeakPolarHBondContact O-CB 3.3Å; M394-L398 PolarHBondContact O-N 3.13Å; L398-L400 HydrophobicContact CB-CB 3.96Å; L398-L400 PolarHBondContact O-N 3.41Å
399	N	89.7	Confident	88.3	Confident	75 Å²	75	42.2 Å²	42.2	40%	0.401	19%	0.19	S	C	.	.			trans	54.4	31.4	-169.7	-164.3	40.7	0	0	0	112.3	Y132 M394 E395	Y132-N399 HydrophobicContact CE2-CB 3.81Å; M394-N399 PolarHBondContact O-N 2.91Å; E395-N399 WeakPolarHBondContact O-CA 3.32Å; E395-N399 PolarHBondContact O-N 3.34Å
400	L	88.4	Confident	88.2	Confident	73 Å²	73	45.6 Å²	45.6	38%	0.382	21%	0.208	S	C	.	.			trans	-100.7	117	-178.2	-174.9	58.6	0	0	0	108.8	M394 L398	M394-L400 HydrophobicContact CE-CB 4.24Å; M394-L400 HydrophobicContact CE-CD2 3.28Å; M394-L400 HydrophobicContact CE-CG 3.72Å; M394-L400 HydrophobicContact CG-CB 4.2Å; L398-L400 HydrophobicContact CB-CB 3.96Å; L398-L400 PolarHBondContact O-N 3.41Å
401	K	82.9	Confident	88	Confident	115 Å²	115	46.1 Å²	46.1	50%	0.5	21%	0.211	S	C	.	.			trans	-91.4	106.5	-178.8	-63.7	-179.8	-179.7	179.5	0	109.2
402	W	83.5	Confident	87.9	Confident	92 Å²	92	46 Å²	46	35%	0.348	21%	0.21	S	C	.	.			trans	-111.1	149.4	175.1	-89.1	28.9	0	0	0	110.7	M394 I410	M394-W402 HydrophobicContact CE-CB 4.1Å; M394-W402 HydrophobicContact CE-CD2 3.24Å; M394-W402 VanDerWaalsContact CE-CE2 3.4Å; M394-W402 HydrophobicContact CE-CE3 3.69Å; M394-W402 HydrophobicContact CE-CG 3.4Å; M394-W402 HydrophobicContact CE-CH2 4.36Å; M394-W402 HydrophobicContact CE-CZ2 4.01Å; M394-W402 HydrophobicContact CE-CZ3 4.19Å; M394-W402 HydrophobicContact SD-CB 4.05Å; M394-W402 HydrophobicContact SD-CD2 4.1Å; M394-W402 HydrophobicContact SD-CE3 4.25Å; M394-W402 HydrophobicContact SD-CG 4Å; W402-I410 HydrophobicContact CE3-CD1 4.3Å; W402-I410 HydrophobicContact CH2-CD1 3.56Å; W402-I410 HydrophobicContact CZ3-CD1 3.25Å; W402-I410 HydrophobicContact CZ3-CG1 4.44Å
403	K	84.3	Confident	87.8	Confident	128 Å²	128	48.6 Å²	48.6	56%	0.557	23%	0.23	S	C	*	.			trans	-69	138.5	172.2	-62	-177.5	179.6	-178.8	0	108.7	W405 Q406 R407	K403-W405 VanDerWaalsContact C-N 3.31Å; K403-W405 PolarHBondContact O-N 3.31Å; K403-Q406 HydrophobicContact CB-CG 4.15Å; K403-Q406 WeakPolarHBondContact O-CB 3.4Å; K403-Q406 PolarHBondContact O-N 2.86Å; K403-R407 PolarHBondContact O-N 3.42Å
404	R	80.8	Confident	87.8	Confident	30 Å²	30	52.6 Å²	52.6	11%	0.113	25%	0.251	C	S	.	.	H	α-helix	trans	-49.2	-49.5	-179.7	-71.5	178.4	-176.6	164.4	7.2	112.6	D194 Q406 R407 V408	D194-R404 IonicContact OD1-CZ 3.75Å; D194-R404 IonicContact OD1-NH1 3.64Å; D194-R404 PolarHBondContact OD1-NH1 2.86Å; D194-R404 WeakPolarHBondContact OD2-CD 3.39Å; D194-R404 IonicContact OD2-CZ 2.7Å; D194-R404 IonicContact OD2-NE 3.57Å; D194-R404 IonicContact OD2-NH1 3.97Å; D194-R404 PolarHBondContact OD2-NH1 2.71Å; R404-Q406 VanDerWaalsContact C-N 3.32Å; R404-Q406 PolarHBondContact O-N 3.45Å; R404-R407 WeakPolarHBondContact O-CB 3.36Å; R404-R407 PolarHBondContact O-N 2.96Å; R404-R407 VanDerWaalsContact O-N 3.14Å; R404-V408 WeakPolarHBondContact O-CG2 3.33Å; R404-V408 PolarHBondContact O-N 2.94Å
405	W	82.4	Confident	87.6	Confident	123 Å²	123	52 Å²	52	47%	0.466	25%	0.248	S	C	.	.	H	α-helix	trans	-60.6	-37	-180	75.4	-94	0	0	0	114.1	L191 K403 R407 L409	L191-W405 HydrophobicContact CD1-CB 3.47Å; L191-W405 VanDerWaalsContact CD1-CB 3.47Å; L191-W405 HydrophobicContact CD2-CB 3.57Å; L191-W405 HydrophobicContact CG-CB 4.17Å; K403-W405 VanDerWaalsContact C-N 3.31Å; K403-W405 PolarHBondContact O-N 3.31Å; W405-R407 VanDerWaalsContact C-N 3.32Å; W405-L409 VanDerWaalsContact O-CB 3.3Å; W405-L409 WeakPolarHBondContact O-CB 3.42Å; W405-L409 PolarHBondContact O-N 3.14Å
406	Q	87.3	Confident	87.6	Confident	68 Å²	68	51.5 Å²	51.5	32%	0.318	25%	0.246	S	C	.	.	H	α-helix	trans	-67.8	-40.2	178.6	-65.2	179.1	-46.8	0	0	110.3	K403 R404 I410	K403-Q406 HydrophobicContact CB-CG 4.15Å; K403-Q406 WeakPolarHBondContact O-CB 3.4Å; K403-Q406 PolarHBondContact O-N 2.86Å; R404-Q406 VanDerWaalsContact C-N 3.32Å; R404-Q406 PolarHBondContact O-N 3.45Å; Q406-I410 WeakPolarHBondContact O-CB 3.33Å; Q406-I410 WeakPolarHBondContact O-CG1 3.02Å; Q406-I410 PolarHBondContact O-N 2.87Å; Q406-I410 VanDerWaalsContact O-N 3.12Å
407	R	87	Confident	87.5	Confident	10 Å²	10	56.6 Å²	56.6	4%	0.038	27%	0.272	C	S	.	.	H	α-helix	trans	-60.8	-55.8	176.2	-172.1	-160	-178.1	77.2	22	111	E148 G390 M394 K403 R404 W405 L409 I410 T411	E148-R407 IonicContact OE1-CZ 3.03Å; E148-R407 IonicContact OE1-NH1 2.65Å; E148-R407 IonicContact OE1-NH2 2.78Å; E148-R407 PolarHBondContact OE1-NH2 3.44Å; E148-R407 IonicContact OE2-NH2 3.93Å; E148-R407 PolarHBondContact OE2-NH2 3.17Å; G390-R407 PolarHBondContact O-NH1 2.93Å; G390-R407 PolarHBondContact O-NH2 3.32Å; M394-R407 PolarHBondContact SD-NH1 2.97Å; M394-R407 VanDerWaalsContact SD-NH1 3.38Å; K403-R407 PolarHBondContact O-N 3.42Å; R404-R407 WeakPolarHBondContact O-CB 3.36Å; R404-R407 PolarHBondContact O-N 2.96Å; R404-R407 VanDerWaalsContact O-N 3.14Å; W405-R407 VanDerWaalsContact C-N 3.32Å; R407-L409 VanDerWaalsContact C-N 3.3Å; R407-L409 PolarHBondContact O-N 3.43Å; R407-I410 PolarHBondContact O-N 3.36Å; R407-I410 VanDerWaalsContact O-N 3.12Å; R407-T411 HydrophobicContact CG-CG2 4.4Å; R407-T411 PolarHBondContact O-N 3.21Å; R407-T411 PolarHBondContact O-OG1 3.03Å
408	V	85.5	Confident	87.2	Confident	2 Å²	2	58.8 Å²	58.8	1%	0.012	29%	0.287	C	S	.	.	H	α-helix	trans	-57.8	-45.9	-178.1	-179	0	0	0	0	110.9	T187 F190 T387 R404 I410 T411 R412	T187-V408 HydrophobicContact CG2-CG1 3.67Å; F190-V408 HydrophobicContact CD1-CG2 3.9Å; F190-V408 HydrophobicContact CE1-CG2 3.71Å; T387-V408 HydrophobicContact CG2-CG2 3.19Å; T387-V408 WeakPolarHBondContact OG1-CG2 3.44Å; R404-V408 WeakPolarHBondContact O-CG2 3.33Å; R404-V408 PolarHBondContact O-N 2.94Å; V408-I410 VanDerWaalsContact C-N 3.28Å; V408-I410 PolarHBondContact O-N 3.28Å; V408-T411 PolarHBondContact O-N 3.4Å; V408-T411 PolarHBondContact O-OG1 3.39Å; V408-R412 WeakPolarHBondContact O-CB 3.16Å; V408-R412 PolarHBondContact O-N 2.72Å
409	L	87	Confident	86.9	Confident	70 Å²	70	56.5 Å²	56.5	37%	0.366	28%	0.275	S	S	.	.	H	α-helix	trans	-57.4	-43.6	178.8	-169	91.8	0	0	0	111.4	W405 R407 S413	W405-L409 VanDerWaalsContact O-CB 3.3Å; W405-L409 WeakPolarHBondContact O-CB 3.42Å; W405-L409 PolarHBondContact O-N 3.14Å; R407-L409 VanDerWaalsContact C-N 3.3Å; R407-L409 PolarHBondContact O-N 3.43Å; L409-S413 WeakPolarHBondContact O-CB 3.39Å; L409-S413 PolarHBondContact O-N 3.28Å; L409-S413 PolarHBondContact O-OG 2.94Å
410	I	89.2	Confident	86.8	Confident	71 Å²	71	55 Å²	55	36%	0.364	27%	0.266	S	S	.	.	H	α-helix	trans	-71.5	-49.4	-178.1	-73.2	167.3	0	0	0	111.4	W402 Q406 R407 V408 R412 S413 I414	W402-I410 HydrophobicContact CE3-CD1 4.3Å; W402-I410 HydrophobicContact CH2-CD1 3.56Å; W402-I410 HydrophobicContact CZ3-CD1 3.25Å; W402-I410 HydrophobicContact CZ3-CG1 4.44Å; Q406-I410 WeakPolarHBondContact O-CB 3.33Å; Q406-I410 WeakPolarHBondContact O-CG1 3.02Å; Q406-I410 PolarHBondContact O-N 2.87Å; Q406-I410 VanDerWaalsContact O-N 3.12Å; R407-I410 PolarHBondContact O-N 3.36Å; R407-I410 VanDerWaalsContact O-N 3.12Å; V408-I410 VanDerWaalsContact C-N 3.28Å; V408-I410 PolarHBondContact O-N 3.28Å; I410-R412 VanDerWaalsContact C-N 3.34Å; I410-R412 PolarHBondContact O-N 3.46Å; I410-S413 PolarHBondContact O-N 3.23Å; I410-I414 HydrophobicContact CG2-CD1 3.92Å; I410-I414 VanDerWaalsContact O-CG1 3.3Å; I410-I414 WeakPolarHBondContact O-CG1 3.42Å; I410-I414 PolarHBondContact O-N 2.85Å
411	T	87.7	Confident	86.7	Confident	12 Å²	12	55.3 Å²	55.3	7%	0.074	27%	0.268	C	S	.	.	H	α-helix	trans	-62.2	-44.9	179.5	55.3	0	0	0	0	110.8	R407 V408 S413 I414 A415	R407-T411 HydrophobicContact CG-CG2 4.4Å; R407-T411 PolarHBondContact O-N 3.21Å; R407-T411 PolarHBondContact O-OG1 3.03Å; V408-T411 PolarHBondContact O-N 3.4Å; V408-T411 PolarHBondContact O-OG1 3.39Å; T411-S413 PolarHBondContact O-N 2.97Å; T411-I414 PolarHBondContact O-N 2.98Å; T411-I414 VanDerWaalsContact O-N 3.16Å; T411-A415 WeakPolarHBondContact O-CB 3.49Å; T411-A415 PolarHBondContact O-N 3.11Å
412	R	89.1	Confident	86.6	Confident	4 Å²	4	50.8 Å²	50.8	2%	0.015	25%	0.25	C	C	.	.	H	α-helix	trans	-64.5	-39.7	178.3	-163.9	73.2	150.8	-168.6	-9.5	111.8	D155 E158 V159 T183 D186 T187 V408 I410 I414 A415 I416	D155-R412 WeakPolarHBondContact OD1-CD 3.35Å; D155-R412 IonicContact OD1-CZ 2.85Å; D155-R412 IonicContact OD1-NE 3.89Å; D155-R412 IonicContact OD1-NH1 3.51Å; D155-R412 PolarHBondContact OD1-NH1 2.91Å; D155-R412 WeakPolarHBondContact OD2-CA 3.38Å; D155-R412 PolarHBondContact OD2-N 2.89Å; E158-R412 IonicContact OE1-CZ 3.24Å; E158-R412 VanDerWaalsContact OE1-CZ 3.23Å; E158-R412 IonicContact OE1-NH1 2.76Å; E158-R412 PolarHBondContact OE1-NH1 2.83Å; E158-R412 IonicContact OE1-NH2 3.21Å; E158-R412 PolarHBondContact OE1-NH2 2.9Å; E158-R412 IonicContact OE2-NH1 3.82Å; E158-R412 PolarHBondContact OE2-NH1 2.84Å; V159-R412 VanDerWaalsContact CG2-CZ 3.48Å; T183-R412 PolarHBondContact O-NE 2.93Å; D186-R412 IonicContact OD2-NH2 3.62Å; T187-R412 HydrophobicContact CG2-CB 3.91Å; T187-R412 HydrophobicContact CG2-CG 3.56Å; V408-R412 WeakPolarHBondContact O-CB 3.16Å; V408-R412 PolarHBondContact O-N 2.72Å; I410-R412 VanDerWaalsContact C-N 3.34Å; I410-R412 PolarHBondContact O-N 3.46Å; R412-I414 VanDerWaalsContact C-N 3.31Å; R412-I414 PolarHBondContact O-N 3.31Å; R412-A415 PolarHBondContact O-N 2.91Å; R412-I416 HydrophobicContact CG-CD1 3.61Å; R412-I416 HydrophobicContact CG-CG1 4.13Å; R412-I416 VanDerWaalsContact O-CB 3.24Å; R412-I416 WeakPolarHBondContact O-CB 3.47Å; R412-I416 WeakPolarHBondContact O-CG1 3.35Å; R412-I416 PolarHBondContact O-N 3.21Å
413	S	89.1	Confident	86.4	Confident	69 Å²	69	47 Å²	47	48%	0.483	24%	0.237	S	C	.	.	H	α-helix	trans	-62.2	-39.8	175.3	-62.9	0	0	0	0	111.9	L409 I410 T411 L417	L409-S413 WeakPolarHBondContact O-CB 3.39Å; L409-S413 PolarHBondContact O-N 3.28Å; L409-S413 PolarHBondContact O-OG 2.94Å; I410-S413 PolarHBondContact O-N 3.23Å; T411-S413 PolarHBondContact O-N 2.97Å; S413-L417 PolarHBondContact O-N 3.23Å
414	I	91	Very high	86.3	Confident	84 Å²	84	44.9 Å²	44.9	43%	0.431	23%	0.234	S	C	.	.	H	α-helix	trans	-69.4	-40.1	176.7	-64	165.6	0	0	0	110.8	I152 I410 T411 R412 P418	I152-I414 HydrophobicContact CD1-CG2 3.95Å; I152-I414 HydrophobicContact CG2-CG2 4.09Å; I410-I414 HydrophobicContact CG2-CD1 3.92Å; I410-I414 VanDerWaalsContact O-CG1 3.3Å; I410-I414 WeakPolarHBondContact O-CG1 3.42Å; I410-I414 PolarHBondContact O-N 2.85Å; T411-I414 PolarHBondContact O-N 2.98Å; T411-I414 VanDerWaalsContact O-N 3.16Å; R412-I414 VanDerWaalsContact C-N 3.31Å; R412-I414 PolarHBondContact O-N 3.31Å; I414-P418 WeakPolarHBondContact O-CD 3.03Å
415	A	88.8	Confident	86.3	Confident	0 Å²	0	51 Å²	51	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-70.1	-40	179.2	0	0	0	0	0	112.8	I152 D155 M156 T411 R412 L417 P418 T419	I152-A415 HydrophobicContact CG2-CB 4.32Å; D155-A415 HydrophobicContact CB-CB 3.9Å; M156-A415 HydrophobicContact CG-CB 3.81Å; M156-A415 WeakPolarHBondContact CG-O 3.45Å; T411-A415 WeakPolarHBondContact O-CB 3.49Å; T411-A415 PolarHBondContact O-N 3.11Å; R412-A415 PolarHBondContact O-N 2.91Å; A415-L417 VanDerWaalsContact C-N 3.34Å; A415-L417 PolarHBondContact O-N 3.31Å; A415-P418 WeakPolarHBondContact O-CD 3.27Å; A415-T419 PolarHBondContact O-OG1 2.92Å
416	I	89.9	Confident	85.8	Confident	8 Å²	8	53 Å²	53	4%	0.041	27%	0.27	C	S	.	.	H	α-helix	trans	-68.4	-34.3	-179.1	-75.8	177.1	0	0	0	111.7	V159 V180 I184 R412 T419 I420	V159-I416 HydrophobicContact CG1-CG1 4.09Å; V159-I416 HydrophobicContact CG2-CG1 3.89Å; V180-I416 HydrophobicContact CG1-CG2 4Å; I184-I416 HydrophobicContact CB-CD1 4.42Å; I184-I416 HydrophobicContact CD1-CD1 4.19Å; I184-I416 HydrophobicContact CG1-CD1 3.29Å; R412-I416 HydrophobicContact CG-CD1 3.61Å; R412-I416 HydrophobicContact CG-CG1 4.13Å; R412-I416 VanDerWaalsContact O-CB 3.24Å; R412-I416 WeakPolarHBondContact O-CB 3.47Å; R412-I416 WeakPolarHBondContact O-CG1 3.35Å; R412-I416 PolarHBondContact O-N 3.21Å; I416-T419 PolarHBondContact O-N 2.83Å; I416-T419 VanDerWaalsContact O-N 3.14Å; I416-I420 HydrophobicContact CG2-CD1 3.27Å; I416-I420 HydrophobicContact CG2-CG1 3.66Å; I416-I420 WeakPolarHBondContact O-CG1 3.41Å; I416-I420 PolarHBondContact O-N 3.27Å
417	L	90.1	Very high	84.8	Confident	106 Å²	106	50.7 Å²	50.7	56%	0.555	26%	0.264	S	S	*	.	H	α-helix	trans	-58	-54.3	-174.6	175.3	67.7	0	0	0	112.5	S413 A415 T419 I420 L421	S413-L417 PolarHBondContact O-N 3.23Å; A415-L417 VanDerWaalsContact C-N 3.34Å; A415-L417 PolarHBondContact O-N 3.31Å; L417-T419 VanDerWaalsContact C-N 3.3Å; L417-T419 PolarHBondContact O-N 3.03Å; L417-I420 PolarHBondContact O-N 3.38Å; L417-L421 HydrophobicContact CD1-CD1 4.14Å; L417-L421 HydrophobicContact CD1-CG 4.29Å; L417-L421 HydrophobicContact CG-CD1 4.19Å; L417-L421 WeakPolarHBondContact O-CG 3.26Å; L417-L421 PolarHBondContact O-N 3.31Å
418	P	86.3	Confident	83.8	Confident	47 Å²	47	52.4 Å²	52.4	31%	0.305	27%	0.274	S	S	.	.	H	α-helix	trans	-57.5	-40.5	173.2	-24	32.5	0	0	0	113.2	M156 I414 A415 L421 T422	M156-P418 HydrophobicContact CE-CB 3.66Å; M156-P418 HydrophobicContact CE-CG 4.23Å; M156-P418 HydrophobicContact SD-CB 4.4Å; M156-P418 HydrophobicContact SD-CG 4.33Å; I414-P418 WeakPolarHBondContact O-CD 3.03Å; A415-P418 WeakPolarHBondContact O-CD 3.27Å; P418-L421 PolarHBondContact O-N 3.31Å; P418-T422 PolarHBondContact O-N 2.82Å; P418-T422 PolarHBondContact O-OG1 2Å; P418-T422 VanDerWaalsContact O-OG1 3.08Å
419	T	85.1	Confident	82.8	Confident	0 Å²	0	55.6 Å²	55.6	0%	0	29%	0.288	C	S	.	.	H	α-helix	trans	-66.4	-41.5	-178.1	-52	0	0	0	0	112.4	V159 I160 V180 A415 I416 L417 T423 L431 M434	V159-T419 HydrophobicContact CG1-CG2 4Å; I160-T419 HydrophobicContact CG1-CG2 4.05Å; V180-T419 HydrophobicContact CG1-CG2 4.1Å; V180-T419 HydrophobicContact CG2-CG2 3.77Å; A415-T419 PolarHBondContact O-OG1 2.92Å; I416-T419 PolarHBondContact O-N 2.83Å; I416-T419 VanDerWaalsContact O-N 3.14Å; L417-T419 VanDerWaalsContact C-N 3.3Å; L417-T419 PolarHBondContact O-N 3.03Å; T419-T423 WeakPolarHBondContact O-CB 3.43Å; T419-T423 VanDerWaalsContact O-CG2 3.31Å; T419-T423 WeakPolarHBondContact O-CG2 3.32Å; T419-T423 PolarHBondContact O-N 2.93Å; T419-T423 PolarHBondContact O-OG1 3.28Å; T419-L431 HydrophobicContact CG2-CD2 4.27Å; T419-M434 HydrophobicContact CG2-CE 3.98Å
420	I	87.5	Confident	82.1	Confident	44 Å²	44	55.6 Å²	55.6	23%	0.226	29%	0.289	C	S	.	.	H	α-helix	trans	-64.3	-45.6	173.1	-69.2	-179.6	0	0	0	110.4	V180 L181 I416 L417 T422 T423 V424	V180-I420 HydrophobicContact CB-CG1 4.42Å; V180-I420 HydrophobicContact CG1-CD1 4.24Å; V180-I420 HydrophobicContact CG1-CG1 3.48Å; V180-I420 VanDerWaalsContact CG1-CG1 3.48Å; L181-I420 HydrophobicContact CD2-CD1 3.5Å; L181-I420 HydrophobicContact CG-CD1 4.14Å; I416-I420 HydrophobicContact CG2-CD1 3.27Å; I416-I420 HydrophobicContact CG2-CG1 3.66Å; I416-I420 WeakPolarHBondContact O-CG1 3.41Å; I416-I420 PolarHBondContact O-N 3.27Å; L417-I420 PolarHBondContact O-N 3.38Å; I420-T422 VanDerWaalsContact C-N 3.33Å; I420-T422 PolarHBondContact O-N 2.92Å; I420-T423 WeakPolarHBondContact CA-OG1 3.17Å; I420-T423 PolarHBondContact O-N 3.05Å; I420-T423 PolarHBondContact O-OG1 2.72Å; I420-V424 HydrophobicContact CG2-CG2 3.95Å; I420-V424 WeakPolarHBondContact O-CB 3.46Å; I420-V424 VanDerWaalsContact O-CG2 3.28Å; I420-V424 WeakPolarHBondContact O-CG2 3.5Å; I420-V424 PolarHBondContact O-N 2.98Å
421	L	86.3	Confident	81.5	Confident	79 Å²	79	52.4 Å²	52.4	41%	0.414	27%	0.272	S	S	.	.	H	α-helix	trans	-59.9	-44.6	179.9	-68.3	173.9	0	0	0	111.2	L417 P418 F425	L417-L421 HydrophobicContact CD1-CD1 4.14Å; L417-L421 HydrophobicContact CD1-CG 4.29Å; L417-L421 HydrophobicContact CG-CD1 4.19Å; L417-L421 WeakPolarHBondContact O-CG 3.26Å; L417-L421 PolarHBondContact O-N 3.31Å; P418-L421 PolarHBondContact O-N 3.31Å; L421-F425 HydrophobicContact CB-CD2 4.36Å; L421-F425 HydrophobicContact CD2-CD2 3.99Å; L421-F425 HydrophobicContact CD2-CE2 3.57Å; L421-F425 WeakPolarHBondContact O-CB 3.46Å; L421-F425 VanDerWaalsContact O-CD2 3.27Å; L421-F425 WeakPolarHBondContact O-CD2 3.39Å; L421-F425 PolarHBondContact O-N 3.04Å
422	T	81.1	Confident	80.9	Confident	19 Å²	19	52 Å²	52	12%	0.117	27%	0.27	C	S	.	.	H	α-helix	trans	-62.9	-49.1	176.6	-58.6	0	0	0	0	111.2	P418 I420 V424 R426 G427 D430 L431	P418-T422 PolarHBondContact O-N 2.82Å; P418-T422 PolarHBondContact O-OG1 2Å; P418-T422 VanDerWaalsContact O-OG1 3.08Å; I420-T422 VanDerWaalsContact C-N 3.33Å; I420-T422 PolarHBondContact O-N 2.92Å; T422-V424 PolarHBondContact O-N 3.44Å; T422-R426 WeakPolarHBondContact O-CA 3.39Å; T422-R426 WeakPolarHBondContact O-CB 3.5Å; T422-R426 PolarHBondContact O-N 3.2Å; T422-G427 PolarHBondContact O-N 3.41Å; T422-D430 HydrophobicContact CG2-CB 3.8Å; T422-L431 HydrophobicContact CG2-CD2 4.38Å
423	T	79.1	Confident	80.3	Confident	13 Å²	13	53 Å²	53	8%	0.08	28%	0.281	C	S	.	.	H	α-helix	trans	-65.5	-34.1	-178.3	51	0	0	0	0	114.2	T419 I420 L431	T419-T423 WeakPolarHBondContact O-CB 3.43Å; T419-T423 VanDerWaalsContact O-CG2 3.31Å; T419-T423 WeakPolarHBondContact O-CG2 3.32Å; T419-T423 PolarHBondContact O-N 2.93Å; T419-T423 PolarHBondContact O-OG1 3.28Å; I420-T423 WeakPolarHBondContact CA-OG1 3.17Å; I420-T423 PolarHBondContact O-N 3.05Å; I420-T423 PolarHBondContact O-OG1 2.72Å; T423-L431 HydrophobicContact CG2-CD1 3.84Å; T423-L431 HydrophobicContact CG2-CD2 3.6Å; T423-L431 HydrophobicContact CG2-CG 3.96Å
424	V	81.9	Confident	79.9	Confident	83 Å²	83	50.8 Å²	50.8	50%	0.503	26%	0.264	S	S	.	.	H	α-helix	trans	-81.7	-41.7	-179.1	173.2	0	0	0	0	111.9	W177 I420 T422	W177-V424 HydrophobicContact CB-CG2 4.4Å; I420-V424 HydrophobicContact CG2-CG2 3.95Å; I420-V424 WeakPolarHBondContact O-CB 3.46Å; I420-V424 VanDerWaalsContact O-CG2 3.28Å; I420-V424 WeakPolarHBondContact O-CG2 3.5Å; I420-V424 PolarHBondContact O-N 2.98Å; T422-V424 PolarHBondContact O-N 3.44Å
425	F	81.4	Confident	79.5	Confident	159 Å²	159	46.9 Å²	46.9	70%	0.697	24%	0.244	S	C	*	.	H	α-helix	trans	-95.8	-30.4	-171.7	-69	-68.1	0	0	0	114.7	L421	L421-F425 HydrophobicContact CB-CD2 4.36Å; L421-F425 HydrophobicContact CD2-CD2 3.99Å; L421-F425 HydrophobicContact CD2-CE2 3.57Å; L421-F425 WeakPolarHBondContact O-CB 3.46Å; L421-F425 VanDerWaalsContact O-CD2 3.27Å; L421-F425 WeakPolarHBondContact O-CD2 3.39Å; L421-F425 PolarHBondContact O-N 3.04Å
426	R	70.7	Confident	79	Confident	165 Å²	165	48.6 Å²	48.6	62%	0.623	25%	0.253	S	S	*	.	T	Hydrogen-bonded Turn	trans	-111.8	-12.8	-175.2	-61.6	-153.9	172.2	90.5	-4.1	114.6	T422 D430	T422-R426 WeakPolarHBondContact O-CA 3.39Å; T422-R426 WeakPolarHBondContact O-CB 3.5Å; T422-R426 PolarHBondContact O-N 3.2Å; R426-D430 HydrophobicContact CB-CB 3.97Å; R426-D430 WeakPolarHBondContact CB-OD2 3.29Å; R426-D430 WeakPolarHBondContact CD-OD2 3.47Å
427	G	67.9	Low	78.6	Confident	20 Å²	20	52.9 Å²	52.9	21%	0.206	27%	0.271	C	S	.	.			trans	92.2	-175.1	-177.9	0	0	0	0	0	112.2	T422	T422-G427 PolarHBondContact O-N 3.41Å
428	I	64.8	Low	78.5	Confident	46 Å²	46	48.1 Å²	48.1	24%	0.236	25%	0.246	C	C	.	.	S	Bend	trans	-81	-37.3	-171	-61.8	174.4	0	0	0	110.7	L176 F345 D430 L431	L176-I428 HydrophobicContact CD1-CB 4.03Å; L176-I428 HydrophobicContact CD1-CD1 3.71Å; L176-I428 HydrophobicContact CD1-CG1 3.74Å; L176-I428 HydrophobicContact CD1-CG2 3.18Å; L176-I428 HydrophobicContact CG-CD1 4.26Å; F345-I428 HydrophobicContact CD1-CG2 4.37Å; F345-I428 HydrophobicContact CE1-CB 4.49Å; F345-I428 HydrophobicContact CE1-CG2 3.37Å; F345-I428 HydrophobicContact CE2-CG2 4.17Å; F345-I428 HydrophobicContact CZ-CB 4.35Å; F345-I428 HydrophobicContact CZ-CG2 3.27Å; I428-D430 PolarHBondContact O-N 2.95Å; I428-D430 VanDerWaalsContact O-N 3.1Å; I428-L431 HydrophobicContact CG2-CD1 4.37Å; I428-L431 VanDerWaalsContact O-CB 3.25Å; I428-L431 WeakPolarHBondContact O-CB 3.41Å; I428-L431 WeakPolarHBondContact O-CG 3.27Å; I428-L431 PolarHBondContact O-N 3.44Å
429	E	64.2	Low	78.5	Confident	68 Å²	68	46 Å²	46	32%	0.318	23%	0.232	S	C	.	.	T	Hydrogen-bonded Turn	trans	-50.1	-31.7	177.4	39	-85.9	-174.8	0	0	114.4	S344 L431	S344-E429 PolarHBondContact OG-OE2 3.34Å; E429-L431 VanDerWaalsContact C-N 3.29Å; E429-L431 PolarHBondContact O-N 3.19Å
430	D	73.2	Confident	78.3	Confident	71 Å²	71	46.9 Å²	46.9	38%	0.38	24%	0.238	S	C	.	.	H	α-helix	trans	-81.7	-4.2	179.8	-87.2	4.8	0	0	0	114.1	T422 R426 I428 M434	T422-D430 HydrophobicContact CG2-CB 3.8Å; R426-D430 HydrophobicContact CB-CB 3.97Å; R426-D430 WeakPolarHBondContact CB-OD2 3.29Å; R426-D430 WeakPolarHBondContact CD-OD2 3.47Å; I428-D430 PolarHBondContact O-N 2.95Å; I428-D430 VanDerWaalsContact O-N 3.1Å; D430-M434 WeakPolarHBondContact O-CB 3.49Å; D430-M434 PolarHBondContact O-N 3.48Å; D430-M434 VanDerWaalsContact O-N 3.08Å
431	L	76.2	Confident	78.2	Confident	4 Å²	4	46.5 Å²	46.5	2%	0.021	24%	0.236	C	C	.	.	H	α-helix	trans	-67	-39.7	173	-71.4	-177.8	0	0	0	112	I160 L176 T419 T422 T423 I428 E429 M434 N435	I160-L431 HydrophobicContact CG1-CD2 4.24Å; I160-L431 HydrophobicContact CG2-CB 4.46Å; I160-L431 HydrophobicContact CG2-CD1 4.42Å; L176-L431 HydrophobicContact CD1-CD1 4.03Å; T419-L431 HydrophobicContact CG2-CD2 4.27Å; T422-L431 HydrophobicContact CG2-CD2 4.38Å; T423-L431 HydrophobicContact CG2-CD1 3.84Å; T423-L431 HydrophobicContact CG2-CD2 3.6Å; T423-L431 HydrophobicContact CG2-CG 3.96Å; I428-L431 HydrophobicContact CG2-CD1 4.37Å; I428-L431 VanDerWaalsContact O-CB 3.25Å; I428-L431 WeakPolarHBondContact O-CB 3.41Å; I428-L431 WeakPolarHBondContact O-CG 3.27Å; I428-L431 PolarHBondContact O-N 3.44Å; E429-L431 VanDerWaalsContact C-N 3.29Å; E429-L431 PolarHBondContact O-N 3.19Å; L431-M434 HydrophobicContact CD2-CE 3.9Å; L431-M434 WeakPolarHBondContact O-CB 3.39Å; L431-M434 PolarHBondContact O-N 3.13Å; L431-N435 PolarHBondContact O-N 2.94Å
432	T	74.8	Confident	78.2	Confident	3 Å²	3	42.8 Å²	42.8	2%	0.018	22%	0.217	C	C	.	.	H	α-helix	trans	-61.5	-50.7	177	-49.2	0	0	0	0	110.3	D351 M434 N435 D436	D351-T432 HydrophobicContact CB-CG2 3.97Å; D351-T432 WeakPolarHBondContact CB-OG1 3.4Å; T432-M434 PolarHBondContact O-N 3Å; T432-N435 PolarHBondContact O-N 3.35Å; T432-D436 VanDerWaalsContact O-CG 3.27Å; T432-D436 PolarHBondContact O-N 2.9Å
433	G	76	Confident	78.3	Confident	25 Å²	25	41.9 Å²	41.9	26%	0.258	21%	0.211	S	C	.	.	H	α-helix	trans	-62.1	-27.6	176.9	0	0	0	0	0	113.5	F437	G433-F437 WeakPolarHBondContact O-CB 3.42Å; G433-F437 PolarHBondContact O-N 3.39Å
434	M	81	Confident	78.6	Confident	23 Å²	23	42.8 Å²	42.8	11%	0.113	22%	0.216	C	C	.	.	H	α-helix	trans	-70.7	-44.5	171.2	-171.4	169.1	75.6	0	0	111.4	M156 I160 T419 D430 L431 T432 F437 L438	M156-M434 HydrophobicContact CE-CE 4Å; M156-M434 HydrophobicContact CE-CG 4.19Å; M156-M434 HydrophobicContact CE-SD 3.57Å; M156-M434 VanDerWaalsContact CE-SD 3.57Å; I160-M434 HydrophobicContact CD1-CE 3.45Å; I160-M434 VanDerWaalsContact CD1-CE 3.45Å; I160-M434 HydrophobicContact CG1-CE 3.83Å; T419-M434 HydrophobicContact CG2-CE 3.98Å; D430-M434 WeakPolarHBondContact O-CB 3.49Å; D430-M434 PolarHBondContact O-N 3.48Å; D430-M434 VanDerWaalsContact O-N 3.08Å; L431-M434 HydrophobicContact CD2-CE 3.9Å; L431-M434 WeakPolarHBondContact O-CB 3.39Å; L431-M434 PolarHBondContact O-N 3.13Å; T432-M434 PolarHBondContact O-N 3Å; M434-F437 WeakPolarHBondContact O-CB 3.25Å; M434-F437 PolarHBondContact O-N 2.9Å; M434-L438 HydrophobicContact CG-CD1 4.26Å; M434-L438 VanDerWaalsContact O-CG 3.24Å; M434-L438 WeakPolarHBondContact O-CG 3.49Å; M434-L438 PolarHBondContact O-N 3.39Å
435	N	82.9	Confident	78.9	Confident	1 Å²	1	39.4 Å²	39.4	1%	0.005	20%	0.195	C	C	.	.	H	α-helix	trans	-63.3	-41.9	177.6	-171.3	61.7	0	0	0	112.4	E85 Q157 I160 L431 T432 F437 L438 N439	E85-N435 WeakPolarHBondContact CB-ND2 3.32Å; E85-N435 VanDerWaalsContact CD-CG 3.5Å; E85-N435 WeakPolarHBondContact CG-ND2 3.48Å; E85-N435 WeakPolarHBondContact OE2-CB 3.24Å; E85-N435 PolarHBondContact OE2-ND2 3.47Å; Q157-N435 WeakPolarHBondContact CG-OD1 3.41Å; Q157-N435 PolarHBondContact NE2-OD1 3.48Å; I160-N435 HydrophobicContact CD1-CB 4.5Å; L431-N435 PolarHBondContact O-N 2.94Å; T432-N435 PolarHBondContact O-N 3.35Å; N435-F437 VanDerWaalsContact C-N 3.3Å; N435-F437 PolarHBondContact O-N 3.35Å; N435-L438 WeakPolarHBondContact O-CB 3.3Å; N435-L438 PolarHBondContact O-N 2.87Å; N435-N439 PolarHBondContact O-N 2.96Å
436	D	78.6	Confident	79.2	Confident	36 Å²	36	31.8 Å²	31.8	19%	0.193	16%	0.162	C	C	.	.	H	α-helix	trans	-58.7	-45.2	175.3	-60.8	-13	0	0	0	110.8	Q89 T432 L438 N439 V440	Q89-D436 PolarHBondContact NE2-OD1 2.84Å; Q89-D436 PolarHBondContact OE1-OD1 2.82Å; Q89-D436 VanDerWaalsContact OE1-OD1 3.07Å; T432-D436 VanDerWaalsContact O-CG 3.27Å; T432-D436 PolarHBondContact O-N 2.9Å; D436-L438 VanDerWaalsContact C-N 3.31Å; D436-L438 PolarHBondContact O-N 3.2Å; D436-N439 PolarHBondContact O-N 3.29Å; D436-V440 WeakPolarHBondContact O-CG2 3.37Å; D436-V440 PolarHBondContact O-N 2.93Å
437	F	81.7	Confident	80	Confident	99 Å²	99	24 Å²	24	43%	0.434	13%	0.132	S	C	.	.	H	α-helix	trans	-62.8	-37.5	175.6	179.7	-97.2	0	0	0	112.4	G433 M434 N435 V440 L441	G433-F437 WeakPolarHBondContact O-CB 3.42Å; G433-F437 PolarHBondContact O-N 3.39Å; M434-F437 WeakPolarHBondContact O-CB 3.25Å; M434-F437 PolarHBondContact O-N 2.9Å; N435-F437 VanDerWaalsContact C-N 3.3Å; N435-F437 PolarHBondContact O-N 3.35Å; F437-V440 PolarHBondContact O-N 3.38Å; F437-L441 WeakPolarHBondContact O-CB 3.41Å; F437-L441 PolarHBondContact O-N 2.84Å
438	L	87.8	Confident	81	Confident	5 Å²	5	23 Å²	23	3%	0.026	12%	0.123	C	C	.	.	H	α-helix	trans	-66.9	-41.1	176.5	-69.2	169.5	0	0	0	111.6	M156 Q157 I160 M434 N435 D436 V440 L441 M442	M156-L438 HydrophobicContact CB-CD1 3.66Å; M156-L438 HydrophobicContact CE-CD1 4.18Å; M156-L438 HydrophobicContact CE-CD2 4.25Å; M156-L438 HydrophobicContact SD-CD2 4.08Å; Q157-L438 HydrophobicContact CG-CB 3.91Å; Q157-L438 HydrophobicContact CG-CD1 3.6Å; Q157-L438 HydrophobicContact CG-CG 4.39Å; I160-L438 HydrophobicContact CD1-CD1 4.45Å; M434-L438 HydrophobicContact CG-CD1 4.26Å; M434-L438 VanDerWaalsContact O-CG 3.24Å; M434-L438 WeakPolarHBondContact O-CG 3.49Å; M434-L438 PolarHBondContact O-N 3.39Å; N435-L438 WeakPolarHBondContact O-CB 3.3Å; N435-L438 PolarHBondContact O-N 2.87Å; D436-L438 VanDerWaalsContact C-N 3.31Å; D436-L438 PolarHBondContact O-N 3.2Å; L438-V440 VanDerWaalsContact C-N 3.32Å; L438-V440 PolarHBondContact O-N 3.43Å; L438-L441 HydrophobicContact CD2-CD2 4.23Å; L438-L441 WeakPolarHBondContact O-CB 3.47Å; L438-L441 PolarHBondContact O-N 3.36Å; L438-L441 VanDerWaalsContact O-N 3.14Å; L438-M442 VanDerWaalsContact O-CG 3.3Å; L438-M442 WeakPolarHBondContact O-CG 3.14Å; L438-M442 PolarHBondContact O-N 3.38Å
439	N	86.4	Confident	82.3	Confident	2 Å²	2	20.9 Å²	20.9	1%	0.011	11%	0.111	C	C	.	.	H	α-helix	trans	-61.6	-41	173.7	-76.9	-27.3	0	0	0	111.8	G82 Q157 N435 D436 M442 S443	G82-N439 PolarHBondContact O-ND2 3.11Å; Q157-N439 PolarHBondContact NE2-OD1 2.67Å; N435-N439 PolarHBondContact O-N 2.96Å; D436-N439 PolarHBondContact O-N 3.29Å; N439-M442 PolarHBondContact O-N 3.39Å; N439-S443 PolarHBondContact O-N 3.24Å; N439-S443 VanDerWaalsContact O-N 3.15Å
440	V	80.1	Confident	83.5	Confident	20 Å²	20	17.6 Å²	17.6	12%	0.121	10%	0.096	C	C	.	.	H	α-helix	trans	-64	-42.2	172.5	172.8	0	0	0	0	111.5	D436 F437 L438 M442 S443 V444 L501	D436-V440 WeakPolarHBondContact O-CG2 3.37Å; D436-V440 PolarHBondContact O-N 2.93Å; F437-V440 PolarHBondContact O-N 3.38Å; L438-V440 VanDerWaalsContact C-N 3.32Å; L438-V440 PolarHBondContact O-N 3.43Å; V440-M442 VanDerWaalsContact C-N 3.28Å; V440-M442 PolarHBondContact O-N 3.3Å; V440-S443 VanDerWaalsContact O-CB 3.32Å; V440-S443 WeakPolarHBondContact O-CB 3.01Å; V440-S443 PolarHBondContact O-N 3.12Å; V440-V444 WeakPolarHBondContact O-CG2 3.43Å; V440-V444 PolarHBondContact O-N 2.96Å; V440-L501 HydrophobicContact CB-CD1 4.32Å; V440-L501 HydrophobicContact CG1-CB 4.42Å; V440-L501 HydrophobicContact CG1-CD1 3.58Å; V440-L501 HydrophobicContact CG2-CD1 3.77Å
441	L	85.6	Confident	84.2	Confident	36 Å²	36	14.7 Å²	14.7	19%	0.188	8%	0.08	C	C	.	.	H	α-helix	trans	-58.1	-41.6	174.6	176.9	66.6	0	0	0	110.9	V149 F437 L438 S443 V444 Q445	V149-L441 HydrophobicContact CG1-CD1 4.36Å; V149-L441 HydrophobicContact CG1-CD2 4.18Å; F437-L441 WeakPolarHBondContact O-CB 3.41Å; F437-L441 PolarHBondContact O-N 2.84Å; L438-L441 HydrophobicContact CD2-CD2 4.23Å; L438-L441 WeakPolarHBondContact O-CB 3.47Å; L438-L441 PolarHBondContact O-N 3.36Å; L438-L441 VanDerWaalsContact O-N 3.14Å; L441-S443 VanDerWaalsContact C-N 3.32Å; L441-S443 PolarHBondContact O-N 2.73Å; L441-V444 WeakPolarHBondContact O-CA 3.45Å; L441-V444 WeakPolarHBondContact O-CB 3.47Å; L441-V444 PolarHBondContact O-N 2.56Å; L441-Q445 HydrophobicContact CD1-CG 4.39Å; L441-Q445 HydrophobicContact CG-CG 4.44Å; L441-Q445 WeakPolarHBondContact O-CG 3.48Å; L441-Q445 PolarHBondContact O-N 2.89Å
442	M	88.2	Confident	84.9	Confident	1 Å²	1	14.5 Å²	14.5	1%	0.005	8%	0.079	C	C	.	.	H	α-helix	trans	-62.5	-38.8	177.6	-67.1	-60.6	-86	0	0	112.3	A150 G255 M259 P260 L438 N439 V440 V444 Q445 L446	A150-M442 HydrophobicContact CB-SD 4.02Å; G255-M442 WeakPolarHBondContact O-CB 3.45Å; M259-M442 HydrophobicContact CB-CE 3.96Å; M259-M442 HydrophobicContact CE-CE 3.9Å; M259-M442 HydrophobicContact CG-CE 3.97Å; P260-M442 VanDerWaalsContact CD-CE 3.48Å; L438-M442 VanDerWaalsContact O-CG 3.3Å; L438-M442 WeakPolarHBondContact O-CG 3.14Å; L438-M442 PolarHBondContact O-N 3.38Å; N439-M442 PolarHBondContact O-N 3.39Å; V440-M442 VanDerWaalsContact C-N 3.28Å; V440-M442 PolarHBondContact O-N 3.3Å; M442-V444 PolarHBondContact O-N 2.87Å; M442-Q445 PolarHBondContact O-N 3.02Å; M442-L446 PolarHBondContact O-N 3.31Å; M442-L446 VanDerWaalsContact O-N 3.16Å
443	S	83.1	Confident	85.7	Confident	0 Å²	0	14.3 Å²	14.3	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-59	-44.8	169.5	176.7	0	0	0	0	111.4	N439 V440 L441 Q445 L446 V494 N498	N439-S443 PolarHBondContact O-N 3.24Å; N439-S443 VanDerWaalsContact O-N 3.15Å; V440-S443 VanDerWaalsContact O-CB 3.32Å; V440-S443 WeakPolarHBondContact O-CB 3.01Å; V440-S443 PolarHBondContact O-N 3.12Å; L441-S443 VanDerWaalsContact C-N 3.32Å; L441-S443 PolarHBondContact O-N 2.73Å; S443-Q445 VanDerWaalsContact C-N 3.27Å; S443-Q445 PolarHBondContact O-N 3.15Å; S443-L446 WeakPolarHBondContact O-CB 3.18Å; S443-L446 PolarHBondContact O-N 2.9Å; S443-V494 WeakPolarHBondContact O-CG1 3.22Å; S443-N498 PolarHBondContact O-ND2 3.16Å; S443-N498 PolarHBondContact OG-ND2 2.97Å; S443-N498 PolarHBondContact OG-OD1 3.36Å; S443-N498 VanDerWaalsContact OG-OD1 3.12Å
444	V	83.4	Confident	86.3	Confident	31 Å²	31	13.7 Å²	13.7	19%	0.188	7%	0.069	C	C	.	.	H	α-helix	trans	-60.8	-34.4	175.8	178.2	0	0	0	0	112.7	V440 L441 M442 P447 N498 Y527	V440-V444 WeakPolarHBondContact O-CG2 3.43Å; V440-V444 PolarHBondContact O-N 2.96Å; L441-V444 WeakPolarHBondContact O-CA 3.45Å; L441-V444 WeakPolarHBondContact O-CB 3.47Å; L441-V444 PolarHBondContact O-N 2.56Å; M442-V444 PolarHBondContact O-N 2.87Å; V444-P447 WeakPolarHBondContact O-CD 3.3Å; V444-N498 WeakPolarHBondContact CA-ND2 3.49Å; V444-N498 HydrophobicContact CG2-CB 3.86Å; V444-N498 VanDerWaalsContact CG2-CG 3.44Å; V444-N498 PolarHBondContact N-ND2 3.31Å; V444-Y527 HydrophobicContact CG1-CD2 4.13Å; V444-Y527 HydrophobicContact CG1-CE2 3.57Å; V444-Y527 WeakPolarHBondContact O-CE2 3.36Å; V444-Y527 PolarHBondContact O-OH 3.43Å; V444-Y527 VanDerWaalsContact O-OH 3.1Å
445	Q	89.8	Confident	86.5	Confident	12 Å²	12	12.9 Å²	12.9	6%	0.056	7%	0.065	C	C	.	.	H	α-helix	trans	-80.6	-18.9	-178.1	-64.2	-57.3	-29.2	0	0	113.8	M146 A150 P260 L441 M442 S443 F448	M146-Q445 PolarHBondContact O-OE1 2.96Å; A150-Q445 HydrophobicContact CB-CB 4.03Å; A150-Q445 HydrophobicContact CB-CG 4.06Å; P260-Q445 HydrophobicContact CG-CB 3.87Å; L441-Q445 HydrophobicContact CD1-CG 4.39Å; L441-Q445 HydrophobicContact CG-CG 4.44Å; L441-Q445 WeakPolarHBondContact O-CG 3.48Å; L441-Q445 PolarHBondContact O-N 2.89Å; M442-Q445 PolarHBondContact O-N 3.02Å; S443-Q445 VanDerWaalsContact C-N 3.27Å; S443-Q445 PolarHBondContact O-N 3.15Å; Q445-F448 WeakPolarHBondContact O-CB 3.49Å; Q445-F448 PolarHBondContact O-N 2.96Å; Q445-F448 VanDerWaalsContact O-N 3.11Å
446	L	87.3	Confident	86.9	Confident	0 Å²	0	12.8 Å²	12.8	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-52.9	-44.7	-174.3	-170.5	159	0	0	0	115	V258 P260 M442 S443 F448 A449 V450 I490 V494	V258-L446 HydrophobicContact CB-CD1 3.79Å; V258-L446 HydrophobicContact CG1-CD1 3.68Å; V258-L446 HydrophobicContact CG1-CG 4.32Å; P260-L446 HydrophobicContact CG-CB 4.35Å; M442-L446 PolarHBondContact O-N 3.31Å; M442-L446 VanDerWaalsContact O-N 3.16Å; S443-L446 WeakPolarHBondContact O-CB 3.18Å; S443-L446 PolarHBondContact O-N 2.9Å; L446-F448 PolarHBondContact O-N 3.44Å; L446-A449 PolarHBondContact O-N 3.41Å; L446-V450 HydrophobicContact CD2-CB 4.09Å; L446-V450 HydrophobicContact CD2-CG2 3.44Å; L446-V450 VanDerWaalsContact CD2-CG2 3.44Å; L446-V450 HydrophobicContact CG-CG2 4.04Å; L446-V450 WeakPolarHBondContact O-CG2 3.4Å; L446-V450 PolarHBondContact O-N 2.98Å; L446-I490 HydrophobicContact CD1-CG2 4.45Å; L446-I490 HydrophobicContact CD2-CG2 3.66Å; L446-V494 HydrophobicContact CD1-CG2 4.42Å
447	P	86.5	Confident	87.4	Confident	0 Å²	0	11.1 Å²	11.1	0%	0	6%	0.056	C	C	.	.	H	α-helix	trans	-58.7	-32.3	179.5	-26.8	38	0	0	0	113.7	V444 A449 I451 V494 V495 V531	V444-P447 WeakPolarHBondContact O-CD 3.3Å; P447-A449 VanDerWaalsContact C-N 3.25Å; P447-A449 PolarHBondContact O-N 3.36Å; P447-I451 HydrophobicContact CB-CD1 3.88Å; P447-I451 VanDerWaalsContact O-CB 3.31Å; P447-I451 WeakPolarHBondContact O-CB 3.46Å; P447-I451 WeakPolarHBondContact O-CD1 3.39Å; P447-I451 VanDerWaalsContact O-CG1 3.27Å; P447-I451 WeakPolarHBondContact O-CG1 3.28Å; P447-I451 PolarHBondContact O-N 3.44Å; P447-V494 HydrophobicContact CG-CG1 4.22Å; P447-V495 HydrophobicContact CG-CG2 4.39Å; P447-V531 HydrophobicContact CB-CG2 4.3Å
448	F	90.2	Very high	87.5	Confident	1 Å²	1	6.8 Å²	6.8	0%	0.004	4%	0.038	C	C	.	.	H	α-helix	trans	-70.6	-19.8	-177.4	-57.8	-52.6	0	0	0	113.8	L143 M146 Y264 Q445 L446 P452 Y527 F530 V531 L534	L143-F448 HydrophobicContact CD2-CB 3.94Å; L143-F448 HydrophobicContact CD2-CD1 4.25Å; L143-F448 HydrophobicContact CD2-CG 4.49Å; L143-F448 WeakPolarHBondContact CD2-O 3.22Å; M146-F448 HydrophobicContact CB-CB 4.21Å; M146-F448 HydrophobicContact CB-CD2 3.67Å; M146-F448 HydrophobicContact CB-CE2 4.24Å; M146-F448 HydrophobicContact CB-CG 3.99Å; M146-F448 HydrophobicContact CG-CD1 4.5Å; M146-F448 HydrophobicContact CG-CD2 3.7Å; M146-F448 HydrophobicContact CG-CE2 3.77Å; M146-F448 HydrophobicContact CG-CG 4.08Å; M146-F448 HydrophobicContact CG-CZ 4.24Å; M146-F448 HydrophobicContact SD-CD2 4.21Å; M146-F448 HydrophobicContact SD-CE2 3.79Å; M146-F448 HydrophobicContact SD-CZ 4.34Å; Y264-F448 PolarHBondContact OH-O 3.39Å; Q445-F448 WeakPolarHBondContact O-CB 3.49Å; Q445-F448 PolarHBondContact O-N 2.96Å; Q445-F448 VanDerWaalsContact O-N 3.11Å; L446-F448 PolarHBondContact O-N 3.44Å; F448-P452 WeakPolarHBondContact O-CD 3.45Å; F448-P452 VanDerWaalsContact O-CG 3.23Å; F448-P452 WeakPolarHBondContact O-CG 3.45Å; F448-Y527 HydrophobicContact CE1-CE2 4.46Å; F448-Y527 AromaticContact CE2-CD2 3.89Å; F448-Y527 HydrophobicContact CE2-CD2 3.89Å; F448-Y527 AromaticContact CE2-CE2 3.53Å; F448-Y527 HydrophobicContact CE2-CE2 3.53Å; F448-Y527 AromaticContact CZ-CD2 3.49Å; F448-Y527 HydrophobicContact CZ-CD2 3.49Å; F448-Y527 VanDerWaalsContact CZ-CD2 3.49Å; F448-Y527 AromaticContact CZ-CE2 3.39Å; F448-Y527 HydrophobicContact CZ-CE2 3.39Å; F448-F530 AromaticContact CD1-CD1 3.96Å; F448-F530 HydrophobicContact CD1-CD1 3.96Å; F448-F530 AromaticContact CD1-CE1 3.97Å; F448-F530 HydrophobicContact CD1-CE1 3.97Å; F448-F530 AromaticContact CE1-CD1 3.42Å; F448-F530 HydrophobicContact CE1-CD1 3.42Å; F448-F530 VanDerWaalsContact CE1-CD1 3.42Å; F448-F530 AromaticContact CE1-CE1 3.91Å; F448-F530 HydrophobicContact CE1-CE1 3.91Å; F448-F530 HydrophobicContact CE1-CG 4.48Å; F448-F530 HydrophobicContact CZ-CD1 4.19Å; F448-V531 HydrophobicContact CE1-CG2 3.72Å; F448-V531 HydrophobicContact CZ-CG2 4.07Å; F448-L534 HydrophobicContact CD1-CD1 3.72Å; F448-L534 HydrophobicContact CE1-CD1 4.28Å
449	A	91.7	Very high	87.4	Confident	0 Å²	0	6.6 Å²	6.6	0%	0	4%	0.037	C	C	.	.	H	α-helix	trans	-99.6	-39.3	173.3	0	0	0	0	0	111.9	P260 F263 Y264 L446 P447 L453	P260-A449 HydrophobicContact CB-CB 3.72Å; P260-A449 WeakPolarHBondContact O-CB 3.48Å; F263-A449 HydrophobicContact CD2-CB 3.71Å; F263-A449 HydrophobicContact CE2-CB 4.37Å; Y264-A449 HydrophobicContact CE2-CB 3.67Å; L446-A449 PolarHBondContact O-N 3.41Å; P447-A449 VanDerWaalsContact C-N 3.25Å; P447-A449 PolarHBondContact O-N 3.36Å; A449-L453 VanDerWaalsContact O-CB 3.27Å; A449-L453 WeakPolarHBondContact O-CB 3.27Å; A449-L453 PolarHBondContact O-N 2.91Å
450	V	88.8	Confident	87.3	Confident	0 Å²	0	11.1 Å²	11.1	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-69.7	-43.3	-178	171.7	0	0	0	0	112.5	L112 F263 L446 L453 L454 A487	L112-V450 HydrophobicContact CD1-CG2 3.88Å; L112-V450 HydrophobicContact CD2-CG1 4.1Å; L112-V450 HydrophobicContact CD2-CG2 4.3Å; F263-V450 HydrophobicContact CD2-CG2 4.44Å; F263-V450 HydrophobicContact CE2-CG2 3.65Å; F263-V450 HydrophobicContact CZ-CG2 4.29Å; L446-V450 HydrophobicContact CD2-CB 4.09Å; L446-V450 HydrophobicContact CD2-CG2 3.44Å; L446-V450 VanDerWaalsContact CD2-CG2 3.44Å; L446-V450 HydrophobicContact CG-CG2 4.04Å; L446-V450 WeakPolarHBondContact O-CG2 3.4Å; L446-V450 PolarHBondContact O-N 2.98Å; V450-L453 PolarHBondContact O-N 2.91Å; V450-L454 HydrophobicContact CG1-CD1 3.73Å; V450-L454 HydrophobicContact CG1-CG 4.14Å; V450-L454 VanDerWaalsContact O-CG 3.27Å; V450-L454 WeakPolarHBondContact O-CG 3.5Å; V450-L454 PolarHBondContact O-N 3.43Å; V450-A487 HydrophobicContact CG1-CB 4.12Å
451	I	88	Confident	87.6	Confident	9 Å²	9	14.1 Å²	14.1	5%	0.046	8%	0.076	C	C	.	.	H	α-helix	trans	-63.2	-49.6	-177.7	-64.9	162	0	0	0	111.7	P447 L453 L454 T455 V531 L534 I535	P447-I451 HydrophobicContact CB-CD1 3.88Å; P447-I451 VanDerWaalsContact O-CB 3.31Å; P447-I451 WeakPolarHBondContact O-CB 3.46Å; P447-I451 WeakPolarHBondContact O-CD1 3.39Å; P447-I451 VanDerWaalsContact O-CG1 3.27Å; P447-I451 WeakPolarHBondContact O-CG1 3.28Å; P447-I451 PolarHBondContact O-N 3.44Å; I451-L453 VanDerWaalsContact C-N 3.32Å; I451-L453 PolarHBondContact O-N 3.38Å; I451-L454 PolarHBondContact O-N 3.32Å; I451-T455 WeakPolarHBondContact O-CB 3.39Å; I451-T455 PolarHBondContact O-N 3.02Å; I451-T455 PolarHBondContact O-OG1 2.92Å; I451-V531 HydrophobicContact CD1-CG1 3.95Å; I451-L534 HydrophobicContact CD1-CB 4.44Å; I451-L534 HydrophobicContact CG2-CB 3.83Å; I451-I535 HydrophobicContact CD1-CD1 4.3Å; I451-I535 HydrophobicContact CD1-CG1 3.8Å; I451-I535 HydrophobicContact CG1-CG1 4.3Å; I451-I535 HydrophobicContact CG2-CG1 4.42Å
452	P	91.3	Very high	87.7	Confident	0 Å²	0	13.6 Å²	13.6	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-58	-43.4	172.9	-27.8	37.8	0	0	0	112.9	L127 Y135 L143 F448 L454 T455 F456	L127-P452 HydrophobicContact CD1-CB 4.27Å; Y135-P452 HydrophobicContact CE2-CB 4.15Å; Y135-P452 HydrophobicContact CE2-CG 4.18Å; L143-P452 HydrophobicContact CD1-CG 4.25Å; L143-P452 HydrophobicContact CD2-CG 4.39Å; F448-P452 WeakPolarHBondContact O-CD 3.45Å; F448-P452 VanDerWaalsContact O-CG 3.23Å; F448-P452 WeakPolarHBondContact O-CG 3.45Å; P452-L454 PolarHBondContact O-N 3.25Å; P452-T455 PolarHBondContact O-N 3.39Å; P452-F456 HydrophobicContact CB-CD2 4.31Å; P452-F456 HydrophobicContact CB-CE2 3.9Å; P452-F456 WeakPolarHBondContact O-CD2 3.4Å; P452-F456 WeakPolarHBondContact O-CG 3.38Å; P452-F456 PolarHBondContact O-N 3.39Å
453	L	91.5	Very high	87.6	Confident	0 Å²	0	13.6 Å²	13.6	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-59.3	-47.9	-178.9	178.3	60.7	0	0	0	112.2	L112 L115 A116 L119 L127 F263 A449 V450 I451 T457	L112-L453 WeakPolarHBondContact O-CD2 3.24Å; L115-L453 HydrophobicContact CB-CD1 4.2Å; L115-L453 HydrophobicContact CB-CD2 4.1Å; L115-L453 HydrophobicContact CB-CG 4.1Å; A116-L453 HydrophobicContact CB-CD1 4.11Å; A116-L453 HydrophobicContact CB-CD2 4.2Å; L119-L453 HydrophobicContact CD2-CD1 4.24Å; L127-L453 HydrophobicContact CD1-CB 4.39Å; L127-L453 HydrophobicContact CD1-CD1 4.45Å; L127-L453 HydrophobicContact CD2-CB 4.18Å; L127-L453 HydrophobicContact CD2-CD1 4.5Å; F263-L453 HydrophobicContact CB-CD2 4.46Å; F263-L453 HydrophobicContact CD1-CD2 4.42Å; F263-L453 HydrophobicContact CG-CD2 4.24Å; A449-L453 VanDerWaalsContact O-CB 3.27Å; A449-L453 WeakPolarHBondContact O-CB 3.27Å; A449-L453 PolarHBondContact O-N 2.91Å; V450-L453 PolarHBondContact O-N 2.91Å; I451-L453 VanDerWaalsContact C-N 3.32Å; I451-L453 PolarHBondContact O-N 3.38Å; L453-T457 HydrophobicContact CD1-CG2 4.01Å; L453-T457 WeakPolarHBondContact O-CB 3.46Å; L453-T457 VanDerWaalsContact O-CG2 3.27Å; L453-T457 WeakPolarHBondContact O-CG2 3.11Å; L453-T457 PolarHBondContact O-N 3.4Å; L453-T457 PolarHBondContact O-OG1 2.93Å
454	L	87.7	Confident	87.7	Confident	12 Å²	12	15.8 Å²	15.8	6%	0.063	9%	0.091	C	C	.	.	H	α-helix	trans	-65.7	-41	177.4	-65	166.9	0	0	0	112.4	L115 V450 I451 P452 T457 S458 V483 A487	L115-L454 HydrophobicContact CD1-CD2 3.79Å; V450-L454 HydrophobicContact CG1-CD1 3.73Å; V450-L454 HydrophobicContact CG1-CG 4.14Å; V450-L454 VanDerWaalsContact O-CG 3.27Å; V450-L454 WeakPolarHBondContact O-CG 3.5Å; V450-L454 PolarHBondContact O-N 3.43Å; I451-L454 PolarHBondContact O-N 3.32Å; P452-L454 PolarHBondContact O-N 3.25Å; L454-T457 WeakPolarHBondContact CA-OG1 3.3Å; L454-T457 PolarHBondContact O-OG1 3.04Å; L454-S458 WeakPolarHBondContact O-CB 3.19Å; L454-S458 PolarHBondContact O-N 2.92Å; L454-S458 PolarHBondContact O-OG 3.09Å; L454-V483 HydrophobicContact CD2-CG1 3.8Å; L454-A487 HydrophobicContact CD1-CB 3.24Å; L454-A487 HydrophobicContact CD2-CB 3.73Å; L454-A487 HydrophobicContact CG-CB 4.01Å
455	T	86.9	Confident	87.7	Confident	5 Å²	5	20.7 Å²	20.7	3%	0.031	11%	0.112	C	C	.	.	H	α-helix	trans	-58	-51.6	179.9	-63.9	0	0	0	0	110	I451 P452 S458 S459 G538 H541 V542	I451-T455 WeakPolarHBondContact O-CB 3.39Å; I451-T455 PolarHBondContact O-N 3.02Å; I451-T455 PolarHBondContact O-OG1 2.92Å; P452-T455 PolarHBondContact O-N 3.39Å; T455-S458 PolarHBondContact O-N 3.15Å; T455-S459 PolarHBondContact O-N 3.32Å; T455-S459 VanDerWaalsContact O-N 3.1Å; T455-G538 VanDerWaalsContact CG2-CA 3.43Å; T455-G538 WeakPolarHBondContact OG1-CA 3.2Å; T455-H541 HydrophobicContact CG2-CB 4.3Å; T455-V542 HydrophobicContact CG2-CG2 4.41Å
456	F	91.1	Very high	87.4	Confident	0 Å²	0	21.8 Å²	21.8	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-75.7	-36.8	-175.4	-57.7	-38.8	0	0	0	112.9	L119 L127 V130 C131 E134 Y135 P452 S458 S459 I462 M463	L119-F456 HydrophobicContact CD1-CB 3.88Å; L127-F456 HydrophobicContact CD1-CD2 3.81Å; L127-F456 HydrophobicContact CD1-CE2 4.31Å; V130-F456 HydrophobicContact CB-CD2 4.13Å; V130-F456 HydrophobicContact CB-CE2 4.33Å; V130-F456 HydrophobicContact CG1-CB 4.05Å; V130-F456 HydrophobicContact CG1-CD1 3.87Å; V130-F456 HydrophobicContact CG1-CD2 3.51Å; V130-F456 HydrophobicContact CG1-CE1 4.18Å; V130-F456 HydrophobicContact CG1-CE2 3.82Å; V130-F456 HydrophobicContact CG1-CG 3.53Å; V130-F456 HydrophobicContact CG1-CZ 4.14Å; C131-F456 HydrophobicContact CB-CE2 4.48Å; E134-F456 HydrophobicContact CB-CE1 3.57Å; E134-F456 HydrophobicContact CB-CZ 3.82Å; E134-F456 HydrophobicContact CG-CD1 4.25Å; E134-F456 HydrophobicContact CG-CE1 3.65Å; E134-F456 HydrophobicContact CG-CZ 4.16Å; Y135-F456 AromaticContact CD2-CZ 3.89Å; Y135-F456 HydrophobicContact CD2-CZ 3.89Å; Y135-F456 HydrophobicContact CE2-CE1 4.44Å; Y135-F456 AromaticContact CE2-CE2 4Å; Y135-F456 HydrophobicContact CE2-CE2 4Å; Y135-F456 AromaticContact CE2-CZ 3.46Å; Y135-F456 HydrophobicContact CE2-CZ 3.46Å; Y135-F456 VanDerWaalsContact CE2-CZ 3.46Å; P452-F456 HydrophobicContact CB-CD2 4.31Å; P452-F456 HydrophobicContact CB-CE2 3.9Å; P452-F456 WeakPolarHBondContact O-CD2 3.4Å; P452-F456 WeakPolarHBondContact O-CG 3.38Å; P452-F456 PolarHBondContact O-N 3.39Å; F456-S458 PolarHBondContact O-N 3.27Å; F456-S459 PolarHBondContact O-N 2.98Å; F456-I462 HydrophobicContact CB-CD1 3.83Å; F456-I462 HydrophobicContact CD1-CD1 3.52Å; F456-I462 HydrophobicContact CE1-CD1 4.4Å; F456-I462 HydrophobicContact CG-CD1 3.93Å; F456-M463 WeakPolarHBondContact O-CG 3.47Å
457	T	88.8	Confident	87.1	Confident	0 Å²	0	24.4 Å²	24.4	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-70.7	-15	174.8	56.3	0	0	0	0	113.8	L115 L119 L453 L454 M463 N468	L115-T457 HydrophobicContact CB-CG2 4.16Å; L115-T457 WeakPolarHBondContact O-CG2 3.31Å; L119-T457 HydrophobicContact CB-CG2 3.94Å; L119-T457 HydrophobicContact CD1-CG2 4.2Å; L453-T457 HydrophobicContact CD1-CG2 4.01Å; L453-T457 WeakPolarHBondContact O-CB 3.46Å; L453-T457 VanDerWaalsContact O-CG2 3.27Å; L453-T457 WeakPolarHBondContact O-CG2 3.11Å; L453-T457 PolarHBondContact O-N 3.4Å; L453-T457 PolarHBondContact O-OG1 2.93Å; L454-T457 WeakPolarHBondContact CA-OG1 3.3Å; L454-T457 PolarHBondContact O-OG1 3.04Å; T457-M463 HydrophobicContact CG2-SD 4.49Å; T457-M463 WeakPolarHBondContact O-CG 3.28Å; T457-N468 PolarHBondContact O-N 3.26Å; T457-N468 VanDerWaalsContact O-N 3.07Å; T457-N468 PolarHBondContact OG1-ND2 3Å; T457-N468 VanDerWaalsContact OG1-ND2 3.16Å
458	S	83.9	Confident	86.5	Confident	9 Å²	9	25.2 Å²	25.2	6%	0.063	13%	0.132	C	C	.	.	H	α-helix	trans	-99.1	-8.9	173.5	-52.4	0	0	0	0	113.5	L454 T455 F456	L454-S458 WeakPolarHBondContact O-CB 3.19Å; L454-S458 PolarHBondContact O-N 2.92Å; L454-S458 PolarHBondContact O-OG 3.09Å; T455-S458 PolarHBondContact O-N 3.15Å; F456-S458 PolarHBondContact O-N 3.27Å
459	S	85.7	Confident	85.1	Confident	0 Å²	0	28.9 Å²	28.9	0%	0	16%	0.158	C	C	.	.			trans	-78.9	126.1	179.7	-170.8	0	0	0	0	110.9	T455 F456 S461 I462 M463 H541 S545	T455-S459 PolarHBondContact O-N 3.32Å; T455-S459 VanDerWaalsContact O-N 3.1Å; F456-S459 PolarHBondContact O-N 2.98Å; S459-S461 VanDerWaalsContact C-N 3.25Å; S459-S461 PolarHBondContact O-N 3.42Å; S459-I462 PolarHBondContact O-N 2.85Å; S459-M463 PolarHBondContact O-N 3.49Å; S459-H541 PolarHBondContact OG-CE1 3.15Å; S459-H541 VanDerWaalsContact OG-CE1 3.26Å; S459-H541 PolarHBondContact OG-ND1 3.38Å; S459-S545 WeakPolarHBondContact OG-CB 3.16Å; S459-S545 PolarHBondContact OG-OG 3.47Å
460	R	84.1	Confident	83.4	Confident	97 Å²	97	35.3 Å²	35.3	37%	0.366	19%	0.192	S	C	.	.	H	α-helix	trans	-67.5	-28.3	177.6	-170.7	-177.9	-173.7	-179.6	-0.1	111.7	I462 A464 K467 S545	R460-I462 VanDerWaalsContact C-N 3.28Å; R460-I462 PolarHBondContact O-N 2.86Å; R460-A464 VanDerWaalsContact O-CA 3.23Å; R460-A464 WeakPolarHBondContact O-CA 3.4Å; R460-A464 PolarHBondContact O-N 3.09Å; R460-K467 HydrophobicContact CB-CD 4.4Å; R460-K467 HydrophobicContact CG-CD 4.47Å; R460-S545 WeakPolarHBondContact CA-OG 3.11Å; R460-S545 WeakPolarHBondContact CB-OG 2.97Å; R460-S545 PolarHBondContact N-OG 3.09Å
461	S	85.4	Confident	81.8	Confident	84 Å²	84	36.5 Å²	36.5	59%	0.587	20%	0.199	S	C	*	.	H	α-helix	trans	-69.3	-29.1	-179.3	-169	0	0	0	0	112.1	S459 S545	S459-S461 VanDerWaalsContact C-N 3.25Å; S459-S461 PolarHBondContact O-N 3.42Å; S461-S545 PolarHBondContact N-OG 3.34Å
462	I	87.8	Confident	80.1	Confident	25 Å²	25	42.6 Å²	42.6	13%	0.128	23%	0.232	C	C	.	.	H	α-helix	trans	-99.5	-45.2	-175.8	-61.8	166.2	0	0	0	110.4	L119 V130 E134 F456 S459 R460	L119-I462 HydrophobicContact CD1-CG2 3.9Å; V130-I462 HydrophobicContact CG1-CD1 3.71Å; E134-I462 HydrophobicContact CG-CD1 4.2Å; F456-I462 HydrophobicContact CB-CD1 3.83Å; F456-I462 HydrophobicContact CD1-CD1 3.52Å; F456-I462 HydrophobicContact CE1-CD1 4.4Å; F456-I462 HydrophobicContact CG-CD1 3.93Å; S459-I462 PolarHBondContact O-N 2.85Å; R460-I462 VanDerWaalsContact C-N 3.28Å; R460-I462 PolarHBondContact O-N 2.86Å
463	M	87.3	Confident	78.4	Confident	0 Å²	0	50 Å²	50	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-93.6	-6.9	-174.9	-64.4	-66.4	-70.1	0	0	114.1	R118 L119 V122 F456 T457 S459 E465 F466 K467	R118-M463 HydrophobicContact CB-CE 4.17Å; L119-M463 HydrophobicContact CD1-SD 4.12Å; V122-M463 HydrophobicContact CB-CE 4.17Å; V122-M463 HydrophobicContact CB-SD 4.11Å; V122-M463 HydrophobicContact CG1-CE 4.45Å; V122-M463 HydrophobicContact CG1-SD 4.19Å; V122-M463 HydrophobicContact CG2-CE 3.92Å; F456-M463 WeakPolarHBondContact O-CG 3.47Å; T457-M463 HydrophobicContact CG2-SD 4.49Å; T457-M463 WeakPolarHBondContact O-CG 3.28Å; S459-M463 PolarHBondContact O-N 3.49Å; M463-E465 PolarHBondContact O-N 3.44Å; M463-F466 HydrophobicContact CE-CB 4.2Å; M463-F466 WeakPolarHBondContact CE-O 3.5Å; M463-F466 WeakPolarHBondContact O-CA 3.29Å; M463-F466 WeakPolarHBondContact O-CB 3.22Å; M463-F466 PolarHBondContact O-N 2.94Å; M463-K467 HydrophobicContact CB-CB 4.08Å
464	A	83.9	Confident	76.5	Confident	46 Å²	46	51.8 Å²	51.8	38%	0.38	27%	0.272	S	S	.	.	G	3₁₀ helix	trans	48.3	-121.4	-175.3	0	0	0	0	0	112	R460 F466	R460-A464 VanDerWaalsContact O-CA 3.23Å; R460-A464 WeakPolarHBondContact O-CA 3.4Å; R460-A464 PolarHBondContact O-N 3.09Å; A464-F466 VanDerWaalsContact C-N 3.33Å
465	E	83.8	Confident	74.9	Confident	135 Å²	135	58.6 Å²	58.6	63%	0.631	30%	0.302	S	S	*	.	G	3₁₀ helix	trans	-72.6	-21.3	176.1	60.7	177.1	-157.8	0	0	113.9	P280 M463 K467	P280-E465 WeakPolarHBondContact CB-OE1 3.39Å; M463-E465 PolarHBondContact O-N 3.44Å; E465-K467 PolarHBondContact O-N 3.37Å
466	F	83.4	Confident	73.2	Confident	35 Å²	35	60.2 Å²	60.2	15%	0.154	31%	0.31	C	S	.	.	G	3₁₀ helix	trans	-83.9	14	179.4	-59.2	-78.8	0	0	0	113.4	R118 V122 P280 V283 R284 M463 A464	R118-F466 PolarHBondContact NH2-O 2.87Å; V122-F466 HydrophobicContact CG1-CB 4.22Å; V122-F466 HydrophobicContact CG1-CD2 3.95Å; V122-F466 HydrophobicContact CG1-CG 4.44Å; V122-F466 HydrophobicContact CG2-CB 3.81Å; V122-F466 HydrophobicContact CG2-CD2 4.03Å; V122-F466 HydrophobicContact CG2-CG 3.93Å; P280-F466 HydrophobicContact CB-CE2 4.3Å; P280-F466 HydrophobicContact CB-CZ 3.93Å; P280-F466 WeakPolarHBondContact O-CZ 3.21Å; V283-F466 HydrophobicContact CB-CE2 4.07Å; V283-F466 HydrophobicContact CB-CZ 3.87Å; V283-F466 HydrophobicContact CG1-CD1 4.45Å; V283-F466 HydrophobicContact CG1-CD2 4.01Å; V283-F466 HydrophobicContact CG1-CE1 4.07Å; V283-F466 HydrophobicContact CG1-CE2 3.6Å; V283-F466 HydrophobicContact CG1-CG 4.43Å; V283-F466 HydrophobicContact CG1-CZ 3.63Å; R284-F466 HydrophobicContact CB-CE1 4.23Å; M463-F466 HydrophobicContact CE-CB 4.2Å; M463-F466 WeakPolarHBondContact CE-O 3.5Å; M463-F466 WeakPolarHBondContact O-CA 3.29Å; M463-F466 WeakPolarHBondContact O-CB 3.22Å; M463-F466 PolarHBondContact O-N 2.94Å; A464-F466 VanDerWaalsContact C-N 3.33Å
467	K	80.9	Confident	71.3	Confident	55 Å²	55	60.7 Å²	60.7	24%	0.239	31%	0.312	C	S	.	.	S	Bend	trans	-60.1	152.4	177.7	72.7	-178.4	-177	-176.5	0	112.1	R460 M463 E465 S469	R460-K467 HydrophobicContact CB-CD 4.4Å; R460-K467 HydrophobicContact CG-CD 4.47Å; M463-K467 HydrophobicContact CB-CB 4.08Å; E465-K467 PolarHBondContact O-N 3.37Å; K467-S469 PolarHBondContact O-N 3.38Å; K467-S469 VanDerWaalsContact O-N 3.13Å
468	N	75	Confident	69.7	Low	16 Å²	16	62.4 Å²	62.4	9%	0.086	32%	0.32	C	S	.	.			trans	-67.2	109.8	169	-66.3	-19.7	0	0	0	109.7	L115 R118 T457	L115-N468 VanDerWaalsContact CD2-ND2 3.34Å; L115-N468 WeakPolarHBondContact CD2-ND2 3.29Å; R118-N468 PolarHBondContact NH1-OD1 3.45Å; T457-N468 PolarHBondContact O-N 3.26Å; T457-N468 VanDerWaalsContact O-N 3.07Å; T457-N468 PolarHBondContact OG1-ND2 3Å; T457-N468 VanDerWaalsContact OG1-ND2 3.16Å
469	S	60.6	Low	68.2	Low	79 Å²	79	65.7 Å²	65.7	55%	0.552	34%	0.34	S	S	*	.			trans	-125.1	122.3	-171.9	-175.4	0	0	0	0	112.7	K467	K467-S469 PolarHBondContact O-N 3.38Å; K467-S469 VanDerWaalsContact O-N 3.13Å
470	L	56.1	Low	66.5	Low	134 Å²	134	71.2 Å²	71.2	70%	0.702	36%	0.364	S	S	*	.	S	Bend	trans	-146.7	5.5	148.4	-140	81.5	0	0	0	114.2
471	T	53.7	Low	65.4	Low	25 Å²	25	66.9 Å²	66.9	15%	0.153	35%	0.348	C	S	.	.			trans	-151	124.4	-174.6	-48.6	0	0	0	0	114.2	Y473 L476 K480 R546	T471-Y473 HydrophobicContact CG2-CD2 4.19Å; T471-Y473 PolarHBondContact O-N 3.35Å; T471-L476 HydrophobicContact CG2-CB 3.82Å; T471-K480 HydrophobicContact CG2-CB 4.47Å; T471-R546 PolarHBondContact O-NH1 2Å; T471-R546 PolarHBondContact O-NH2 3.32Å
472	N	54	Low	64.3	Low	137 Å²	137	66.3 Å²	66.3	73%	0.733	34%	0.343	S	S	*	.	S	Bend	trans	-70.3	-12.9	178.1	-78.2	-21.4	0	0	0	114.3	R546	N472-R546 PolarHBondContact O-NH1 3.02Å
473	Y	55.6	Low	63.1	Low	156 Å²	156	66.2 Å²	66.2	61%	0.612	34%	0.343	S	S	*	.			trans	-102.8	125.7	-177.2	-56.6	-75.2	0	0	0	112.2	T471 L476 M477	T471-Y473 HydrophobicContact CG2-CD2 4.19Å; T471-Y473 PolarHBondContact O-N 3.35Å; Y473-L476 HydrophobicContact CD2-CD1 3.92Å; Y473-L476 HydrophobicContact CG-CD1 4.08Å; Y473-L476 CarbonylContact O-C 3.53Å; Y473-L476 PolarHBondContact O-N 3.14Å; Y473-M477 PolarHBondContact O-N 3.11Å
474	P	51.2	Low	61.9	Low	37 Å²	37	66.4 Å²	66.4	24%	0.24	35%	0.345	C	S	.	.	S	Bend	trans	-70	-38.8	-175.3	25.2	-32.2	0	0	0	113.4	L476 M477	P474-L476 PolarHBondContact O-N 2.94Å; P474-M477 VanDerWaalsContact O-CB 3.29Å; P474-M477 WeakPolarHBondContact O-CB 3.36Å; P474-M477 PolarHBondContact O-N 2.84Å
475	F	54.1	Low	61.1	Low	156 Å²	156	67.2 Å²	67.2	68%	0.684	34%	0.342	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.5	-34.9	173.2	-176.5	-102.6	0	0	0	112	M477 T479	F475-M477 VanDerWaalsContact C-N 3.31Å; F475-T479 PolarHBondContact O-OG1 3.5Å
476	L	51	Low	60.2	Low	39 Å²	39	63.5 Å²	63.5	20%	0.204	33%	0.328	C	S	.	.	T	Hydrogen-bonded Turn	trans	-82.6	-7.1	175.8	-68.2	166.7	0	0	0	112.8	T471 Y473 P474 F478 T479 K480	T471-L476 HydrophobicContact CG2-CB 3.82Å; Y473-L476 HydrophobicContact CD2-CD1 3.92Å; Y473-L476 HydrophobicContact CG-CD1 4.08Å; Y473-L476 CarbonylContact O-C 3.53Å; Y473-L476 PolarHBondContact O-N 3.14Å; P474-L476 PolarHBondContact O-N 2.94Å; L476-F478 VanDerWaalsContact C-N 3.34Å; L476-F478 PolarHBondContact O-N 3.06Å; L476-T479 VanDerWaalsContact CA-OG1 3.31Å; L476-T479 WeakPolarHBondContact CA-OG1 3.32Å; L476-T479 CarbonylContact O-C 3.43Å; L476-T479 PolarHBondContact O-N 2.78Å; L476-K480 HydrophobicContact CB-CB 4.24Å; L476-K480 HydrophobicContact CB-CD 3.93Å; L476-K480 HydrophobicContact CB-CG 4.1Å; L476-K480 HydrophobicContact CD1-CD 3.96Å; L476-K480 HydrophobicContact CD2-CD 3.57Å; L476-K480 HydrophobicContact CD2-CG 3.84Å; L476-K480 HydrophobicContact CG-CD 4.01Å; L476-K480 HydrophobicContact CG-CG 4.47Å; L476-K480 WeakPolarHBondContact O-CA 3.24Å; L476-K480 WeakPolarHBondContact O-CB 3.17Å; L476-K480 PolarHBondContact O-N 3.13Å
477	M	51.5	Low	59.2	Low	9 Å²	9	61.8 Å²	61.8	4%	0.044	32%	0.321	C	S	.	.	H	α-helix	trans	-69.2	-37.8	-177.5	-162.4	-177.6	96.2	0	0	111.4	Y473 P474 F475 T479 S481 S484 V542 R546	Y473-M477 PolarHBondContact O-N 3.11Å; P474-M477 VanDerWaalsContact O-CB 3.29Å; P474-M477 WeakPolarHBondContact O-CB 3.36Å; P474-M477 PolarHBondContact O-N 2.84Å; F475-M477 VanDerWaalsContact C-N 3.31Å; M477-T479 VanDerWaalsContact C-N 3.3Å; M477-S481 VanDerWaalsContact O-CB 3.32Å; M477-S481 WeakPolarHBondContact O-CB 3.12Å; M477-S481 PolarHBondContact O-N 2.86Å; M477-S484 VanDerWaalsContact O-CB 3.23Å; M477-S484 WeakPolarHBondContact O-CB 3.4Å; M477-V542 HydrophobicContact CE-CB 4.2Å; M477-V542 HydrophobicContact CE-CG1 3.45Å; M477-V542 VanDerWaalsContact CE-CG1 3.45Å; M477-V542 HydrophobicContact CE-CG2 3.91Å; M477-V542 HydrophobicContact SD-CG1 3.41Å; M477-V542 WeakPolarHBondContact SD-CG1 3.39Å; M477-R546 PolarHBondContact SD-NH2 3.37Å
478	F	54	Low	58.5	Low	36 Å²	36	61 Å²	61	16%	0.158	32%	0.319	C	S	.	.	H	α-helix	trans	-74.4	-21.3	175.2	-72.5	-91.6	0	0	0	113.1	L476 S484 N488 F539	L476-F478 VanDerWaalsContact C-N 3.34Å; L476-F478 PolarHBondContact O-N 3.06Å; F478-S484 WeakPolarHBondContact CA-OG 3.46Å; F478-N488 PolarHBondContact O-ND2 3.4Å; F478-F539 AromaticContact CD2-CD2 3.54Å; F478-F539 HydrophobicContact CD2-CD2 3.54Å; F478-F539 HydrophobicContact CD2-CE2 4.13Å; F478-F539 HydrophobicContact CE2-CB 3.87Å; F478-F539 AromaticContact CE2-CD2 3.38Å; F478-F539 HydrophobicContact CE2-CD2 3.38Å; F478-F539 HydrophobicContact CE2-CE2 4.31Å; F478-F539 HydrophobicContact CE2-CG 4.08Å; F478-F539 HydrophobicContact CZ-CB 4.16Å; F478-F539 HydrophobicContact CZ-CD2 4.4Å
479	T	52.7	Low	58.3	Low	78 Å²	78	65.7 Å²	65.7	48%	0.479	34%	0.344	S	S	.	.	H	α-helix	trans	-112.9	-12.3	-173	55	0	0	0	0	114.9	F475 L476 M477 I485	F475-T479 PolarHBondContact O-OG1 3.5Å; L476-T479 VanDerWaalsContact CA-OG1 3.31Å; L476-T479 WeakPolarHBondContact CA-OG1 3.32Å; L476-T479 CarbonylContact O-C 3.43Å; L476-T479 PolarHBondContact O-N 2.78Å; M477-T479 VanDerWaalsContact C-N 3.3Å; T479-I485 VanDerWaalsContact O-CD1 3.23Å; T479-I485 WeakPolarHBondContact O-CD1 3.41Å; T479-I485 VanDerWaalsContact O-CG1 3.28Å; T479-I485 WeakPolarHBondContact O-CG1 3.44Å
480	K	50.3	Low	58.7	Low	117 Å²	117	62.3 Å²	62.3	51%	0.509	32%	0.319	S	S	.	.	H	α-helix	trans	-128	-18.9	-176.9	-70.6	-170.6	176.9	170.2	0	115.4	T471 L476 P482	T471-K480 HydrophobicContact CG2-CB 4.47Å; L476-K480 HydrophobicContact CB-CB 4.24Å; L476-K480 HydrophobicContact CB-CD 3.93Å; L476-K480 HydrophobicContact CB-CG 4.1Å; L476-K480 HydrophobicContact CD1-CD 3.96Å; L476-K480 HydrophobicContact CD2-CD 3.57Å; L476-K480 HydrophobicContact CD2-CG 3.84Å; L476-K480 HydrophobicContact CG-CD 4.01Å; L476-K480 HydrophobicContact CG-CG 4.47Å; L476-K480 WeakPolarHBondContact O-CA 3.24Å; L476-K480 WeakPolarHBondContact O-CB 3.17Å; L476-K480 PolarHBondContact O-N 3.13Å; K480-P482 WeakPolarHBondContact O-CD 3.49Å
481	S	61.3	Low	59.2	Low	6 Å²	6	56.2 Å²	56.2	4%	0.042	29%	0.288	C	S	.	.	S	Bend	trans	-69.6	121.7	168.9	-178.3	0	0	0	0	107.5	M477 V483 S484 I485	M477-S481 VanDerWaalsContact O-CB 3.32Å; M477-S481 WeakPolarHBondContact O-CB 3.12Å; M477-S481 PolarHBondContact O-N 2.86Å; S481-V483 PolarHBondContact O-N 2.86Å; S481-V483 VanDerWaalsContact O-N 3.1Å; S481-S484 PolarHBondContact O-N 3.34Å; S481-I485 WeakPolarHBondContact O-CG1 3.31Å; S481-I485 PolarHBondContact O-N 2.96Å
482	P	63.3	Low	60	Low	72 Å²	72	59.3 Å²	59.3	47%	0.468	31%	0.307	S	S	.	.	H	α-helix	trans	-54.5	-36.1	180	20.3	-31.2	0	0	0	111.1	K480 I485 V486	K480-P482 WeakPolarHBondContact O-CD 3.49Å; P482-I485 PolarHBondContact O-N 3.35Å; P482-V486 WeakPolarHBondContact O-CB 3.43Å; P482-V486 VanDerWaalsContact O-CG2 3.26Å; P482-V486 WeakPolarHBondContact O-CG2 3.46Å; P482-V486 PolarHBondContact O-N 2.87Å
483	V	62.4	Low	60.9	Low	22 Å²	22	54.8 Å²	54.8	13%	0.133	29%	0.288	C	S	.	.	H	α-helix	trans	-57	-48.6	173.2	172.7	0	0	0	0	112.7	F111 L115 L454 S481 A487	F111-V483 HydrophobicContact CE1-CB 4.26Å; F111-V483 HydrophobicContact CE1-CG1 3.72Å; F111-V483 HydrophobicContact CE1-CG2 4.42Å; F111-V483 HydrophobicContact CE2-CG2 3.88Å; F111-V483 HydrophobicContact CZ-CB 3.64Å; F111-V483 HydrophobicContact CZ-CG1 3.37Å; F111-V483 HydrophobicContact CZ-CG2 3.37Å; L115-V483 HydrophobicContact CD1-CG1 3.91Å; L454-V483 HydrophobicContact CD2-CG1 3.8Å; S481-V483 PolarHBondContact O-N 2.86Å; S481-V483 VanDerWaalsContact O-N 3.1Å; V483-A487 WeakPolarHBondContact O-CB 3.4Å; V483-A487 PolarHBondContact O-N 2.92Å; V483-A487 VanDerWaalsContact O-N 3.09Å
484	S	60.6	Low	61.5	Low	5 Å²	5	47.3 Å²	47.3	4%	0.035	26%	0.259	C	S	.	.	H	α-helix	trans	-79.1	-31.8	-177.3	-164.8	0	0	0	0	112.1	M477 F478 S481 A487 N488	M477-S484 VanDerWaalsContact O-CB 3.23Å; M477-S484 WeakPolarHBondContact O-CB 3.4Å; F478-S484 WeakPolarHBondContact CA-OG 3.46Å; S481-S484 PolarHBondContact O-N 3.34Å; S484-A487 PolarHBondContact O-N 3.11Å; S484-N488 WeakPolarHBondContact O-CB 3.3Å; S484-N488 PolarHBondContact O-N 3.45Å; S484-N488 PolarHBondContact O-ND2 3.49Å; S484-N488 PolarHBondContact OG-ND2 3.4Å; S484-N488 VanDerWaalsContact OG-ND2 3.09Å
485	I	66.8	Low	62.5	Low	63 Å²	63	46.5 Å²	46.5	32%	0.323	25%	0.253	S	S	.	.	H	α-helix	trans	-60.1	-53.3	172.9	-65.4	168.1	0	0	0	108.5	T479 S481 P482 A487 N488 L489	T479-I485 VanDerWaalsContact O-CD1 3.23Å; T479-I485 WeakPolarHBondContact O-CD1 3.41Å; T479-I485 VanDerWaalsContact O-CG1 3.28Å; T479-I485 WeakPolarHBondContact O-CG1 3.44Å; S481-I485 WeakPolarHBondContact O-CG1 3.31Å; S481-I485 PolarHBondContact O-N 2.96Å; P482-I485 PolarHBondContact O-N 3.35Å; I485-A487 VanDerWaalsContact C-N 3.31Å; I485-A487 PolarHBondContact O-N 3.06Å; I485-N488 PolarHBondContact O-N 3.14Å; I485-L489 HydrophobicContact CG2-CD1 3.72Å; I485-L489 HydrophobicContact CG2-CG 4.18Å; I485-L489 VanDerWaalsContact O-CB 3.31Å; I485-L489 WeakPolarHBondContact O-CB 3.5Å; I485-L489 WeakPolarHBondContact O-CG 3.36Å; I485-L489 PolarHBondContact O-N 2.89Å
486	V	65.6	Low	63.4	Low	56 Å²	56	42.2 Å²	42.2	34%	0.339	24%	0.242	S	C	.	.	H	α-helix	trans	-57.2	-47.4	179.6	171.2	0	0	0	0	110.2	M108 P482 L489 I490	M108-V486 HydrophobicContact CE-CG1 4.47Å; M108-V486 HydrophobicContact CG-CG1 4.41Å; P482-V486 WeakPolarHBondContact O-CB 3.43Å; P482-V486 VanDerWaalsContact O-CG2 3.26Å; P482-V486 WeakPolarHBondContact O-CG2 3.46Å; P482-V486 PolarHBondContact O-N 2.87Å; V486-L489 WeakPolarHBondContact O-CB 3.41Å; V486-L489 PolarHBondContact O-N 3.28Å; V486-I490 HydrophobicContact CG1-CD1 4.04Å; V486-I490 VanDerWaalsContact O-CG1 3.23Å; V486-I490 WeakPolarHBondContact O-CG1 3.29Å; V486-I490 PolarHBondContact O-N 3.35Å
487	A	62.6	Low	64.3	Low	0 Å²	0	42.5 Å²	42.5	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-76.5	-27.4	-175.3	0	0	0	0	0	114.7	V450 L454 V483 S484 I485 S491	V450-A487 HydrophobicContact CG1-CB 4.12Å; L454-A487 HydrophobicContact CD1-CB 3.24Å; L454-A487 HydrophobicContact CD2-CB 3.73Å; L454-A487 HydrophobicContact CG-CB 4.01Å; V483-A487 WeakPolarHBondContact O-CB 3.4Å; V483-A487 PolarHBondContact O-N 2.92Å; V483-A487 VanDerWaalsContact O-N 3.09Å; S484-A487 PolarHBondContact O-N 3.11Å; I485-A487 VanDerWaalsContact C-N 3.31Å; I485-A487 PolarHBondContact O-N 3.06Å; A487-S491 WeakPolarHBondContact O-CB 3.5Å; A487-S491 PolarHBondContact O-N 3.14Å; A487-S491 PolarHBondContact O-OG 3.43Å
488	N	65.9	Low	65.2	Low	39 Å²	39	42.3 Å²	42.3	21%	0.209	24%	0.243	C	C	.	.	H	α-helix	trans	-70.2	-40.2	167.4	-74.8	-40.1	0	0	0	110.9	F478 S484 I485 I490 S491 V492	F478-N488 PolarHBondContact O-ND2 3.4Å; S484-N488 WeakPolarHBondContact O-CB 3.3Å; S484-N488 PolarHBondContact O-N 3.45Å; S484-N488 PolarHBondContact O-ND2 3.49Å; S484-N488 PolarHBondContact OG-ND2 3.4Å; S484-N488 VanDerWaalsContact OG-ND2 3.09Å; I485-N488 PolarHBondContact O-N 3.14Å; N488-I490 VanDerWaalsContact C-N 3.32Å; N488-I490 PolarHBondContact O-N 2.69Å; N488-S491 PolarHBondContact O-N 2.85Å; N488-V492 VanDerWaalsContact O-CB 3.3Å; N488-V492 WeakPolarHBondContact O-CB 3.39Å; N488-V492 WeakPolarHBondContact O-CG2 3.37Å; N488-V492 PolarHBondContact O-N 3.29Å
489	L	71.8	Confident	66	Low	114 Å²	114	43.8 Å²	43.8	60%	0.597	25%	0.252	S	S	*	.	H	α-helix	trans	-61.4	-42	173.7	-73.6	174.4	0	0	0	110.8	I485 V486 A493	I485-L489 HydrophobicContact CG2-CD1 3.72Å; I485-L489 HydrophobicContact CG2-CG 4.18Å; I485-L489 VanDerWaalsContact O-CB 3.31Å; I485-L489 WeakPolarHBondContact O-CB 3.5Å; I485-L489 WeakPolarHBondContact O-CG 3.36Å; I485-L489 PolarHBondContact O-N 2.89Å; V486-L489 WeakPolarHBondContact O-CB 3.41Å; V486-L489 PolarHBondContact O-N 3.28Å; L489-A493 WeakPolarHBondContact O-CB 3.39Å; L489-A493 PolarHBondContact O-N 3.27Å
490	I	67.4	Low	66.9	Low	7 Å²	7	43.6 Å²	43.6	4%	0.036	24%	0.244	C	C	.	.	H	α-helix	trans	-58.1	-55.5	171.2	-67.8	167.9	0	0	0	110	M108 L112 L446 V486 N488 V492 A493 V494	M108-I490 HydrophobicContact CB-CD1 4.33Å; M108-I490 HydrophobicContact CE-CB 4.36Å; M108-I490 HydrophobicContact CE-CD1 3.14Å; M108-I490 HydrophobicContact CE-CG1 2.95Å; M108-I490 HydrophobicContact CG-CD1 4.48Å; L112-I490 HydrophobicContact CD1-CD1 4.4Å; L446-I490 HydrophobicContact CD1-CG2 4.45Å; L446-I490 HydrophobicContact CD2-CG2 3.66Å; V486-I490 HydrophobicContact CG1-CD1 4.04Å; V486-I490 VanDerWaalsContact O-CG1 3.23Å; V486-I490 WeakPolarHBondContact O-CG1 3.29Å; V486-I490 PolarHBondContact O-N 3.35Å; N488-I490 VanDerWaalsContact C-N 3.32Å; N488-I490 PolarHBondContact O-N 2.69Å; I490-V492 VanDerWaalsContact C-N 3.28Å; I490-V492 PolarHBondContact O-N 2.83Å; I490-A493 PolarHBondContact O-N 2.96Å; I490-V494 HydrophobicContact CG2-CG2 3.82Å; I490-V494 WeakPolarHBondContact O-CB 3.5Å; I490-V494 WeakPolarHBondContact O-CG2 3.21Å; I490-V494 PolarHBondContact O-N 2.98Å
491	S	66.6	Low	67.7	Low	7 Å²	7	38.5 Å²	38.5	5%	0.049	22%	0.223	C	C	.	.	H	α-helix	trans	-61.1	-40.5	-174.7	-58.2	0	0	0	0	111.1	A487 N488 V495	A487-S491 WeakPolarHBondContact O-CB 3.5Å; A487-S491 PolarHBondContact O-N 3.14Å; A487-S491 PolarHBondContact O-OG 3.43Å; N488-S491 PolarHBondContact O-N 2.85Å; S491-V495 WeakPolarHBondContact O-CB 3.43Å; S491-V495 WeakPolarHBondContact O-CG2 3.4Å; S491-V495 PolarHBondContact O-N 3.24Å
492	V	72	Confident	68	Low	90 Å²	90	38.7 Å²	38.7	55%	0.545	23%	0.226	S	C	.	.	H	α-helix	trans	-68.7	-44.2	175.9	171.3	0	0	0	0	111.1	N488 I490 V495 S496	N488-V492 VanDerWaalsContact O-CB 3.3Å; N488-V492 WeakPolarHBondContact O-CB 3.39Å; N488-V492 WeakPolarHBondContact O-CG2 3.37Å; N488-V492 PolarHBondContact O-N 3.29Å; I490-V492 VanDerWaalsContact C-N 3.28Å; I490-V492 PolarHBondContact O-N 2.83Å; V492-V495 PolarHBondContact O-N 2.91Å; V492-S496 WeakPolarHBondContact O-CB 3.42Å; V492-S496 PolarHBondContact O-N 3.48Å; V492-S496 PolarHBondContact O-OG 3.48Å
493	A	72	Confident	68.2	Low	41 Å²	41	37.5 Å²	37.5	34%	0.339	22%	0.219	S	C	.	.	H	α-helix	trans	-61.2	-54.2	177.5	0	0	0	0	0	110	L489 I490 V495 S496 I497	L489-A493 WeakPolarHBondContact O-CB 3.39Å; L489-A493 PolarHBondContact O-N 3.27Å; I490-A493 PolarHBondContact O-N 2.96Å; A493-V495 PolarHBondContact O-N 3.02Å; A493-S496 PolarHBondContact O-N 3.34Å; A493-I497 HydrophobicContact CB-CD1 4.46Å; A493-I497 WeakPolarHBondContact O-CB 3.26Å; A493-I497 WeakPolarHBondContact O-CD1 3.38Å; A493-I497 WeakPolarHBondContact O-CG1 3.2Å; A493-I497 PolarHBondContact O-N 3.05Å
494	V	68.9	Low	68.4	Low	0 Å²	0	39 Å²	39	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-53.4	-51.1	175.3	167.6	0	0	0	0	110.9	L254 S443 L446 P447 I490 I497 N498	L254-V494 HydrophobicContact CD2-CG2 3.5Å; L254-V494 VanDerWaalsContact CD2-CG2 3.5Å; L254-V494 HydrophobicContact CG-CG2 4.48Å; S443-V494 WeakPolarHBondContact O-CG1 3.22Å; L446-V494 HydrophobicContact CD1-CG2 4.42Å; P447-V494 HydrophobicContact CG-CG1 4.22Å; I490-V494 HydrophobicContact CG2-CG2 3.82Å; I490-V494 WeakPolarHBondContact O-CB 3.5Å; I490-V494 WeakPolarHBondContact O-CG2 3.21Å; I490-V494 PolarHBondContact O-N 2.98Å; V494-I497 PolarHBondContact O-N 3.32Å; V494-N498 WeakPolarHBondContact CG1-ND2 3.01Å; V494-N498 WeakPolarHBondContact O-CB 3.2Å; V494-N498 PolarHBondContact O-N 3.01Å; V494-N498 PolarHBondContact O-ND2 3.36Å
495	V	71.1	Confident	68.7	Low	19 Å²	19	40.7 Å²	40.7	12%	0.115	24%	0.238	C	C	.	.	H	α-helix	trans	-63.7	-44.9	178.5	169.7	0	0	0	0	111.5	P447 S491 V492 A493 I497 N498 L499 Y527 L528	P447-V495 HydrophobicContact CG-CG2 4.39Å; S491-V495 WeakPolarHBondContact O-CB 3.43Å; S491-V495 WeakPolarHBondContact O-CG2 3.4Å; S491-V495 PolarHBondContact O-N 3.24Å; V492-V495 PolarHBondContact O-N 2.91Å; A493-V495 PolarHBondContact O-N 3.02Å; V495-I497 VanDerWaalsContact C-N 3.32Å; V495-I497 PolarHBondContact O-N 3.33Å; V495-N498 PolarHBondContact O-N 3.44Å; V495-L499 HydrophobicContact CG1-CD1 3.87Å; V495-L499 HydrophobicContact CG1-CG 4.24Å; V495-L499 WeakPolarHBondContact O-CB 3.5Å; V495-L499 WeakPolarHBondContact O-CG 3.27Å; V495-L499 PolarHBondContact O-N 3.06Å; V495-Y527 HydrophobicContact CG2-CE1 4.32Å; V495-L528 HydrophobicContact CG1-CD2 3.52Å
496	S	72.9	Confident	68.7	Low	66 Å²	66	38.5 Å²	38.5	46%	0.462	23%	0.227	S	C	.	.	H	α-helix	trans	-62.8	-42.9	179.9	-57.3	0	0	0	0	111.4	V492 A493 F500	V492-S496 WeakPolarHBondContact O-CB 3.42Å; V492-S496 PolarHBondContact O-N 3.48Å; V492-S496 PolarHBondContact O-OG 3.48Å; A493-S496 PolarHBondContact O-N 3.34Å; S496-F500 WeakPolarHBondContact O-CB 3.47Å; S496-F500 PolarHBondContact O-N 2.7Å
497	I	70.5	Confident	68.7	Low	46 Å²	46	42.7 Å²	42.7	24%	0.236	24%	0.241	C	C	.	.	H	α-helix	trans	-63.3	-46.2	175.1	-79.4	167.9	0	0	0	110.9	V251 A493 V494 V495 L499 F500 L501	V251-I497 HydrophobicContact CB-CG2 3.72Å; V251-I497 HydrophobicContact CG1-CG2 3.18Å; V251-I497 HydrophobicContact CG2-CB 4.27Å; V251-I497 HydrophobicContact CG2-CD1 4.24Å; V251-I497 HydrophobicContact CG2-CG1 4.25Å; V251-I497 HydrophobicContact CG2-CG2 3.12Å; A493-I497 HydrophobicContact CB-CD1 4.46Å; A493-I497 WeakPolarHBondContact O-CB 3.26Å; A493-I497 WeakPolarHBondContact O-CD1 3.38Å; A493-I497 WeakPolarHBondContact O-CG1 3.2Å; A493-I497 PolarHBondContact O-N 3.05Å; V494-I497 PolarHBondContact O-N 3.32Å; V495-I497 VanDerWaalsContact C-N 3.32Å; V495-I497 PolarHBondContact O-N 3.33Å; I497-L499 VanDerWaalsContact C-N 3.34Å; I497-L499 PolarHBondContact O-N 2.87Å; I497-F500 CarbonylContact O-C 3.6Å; I497-F500 WeakPolarHBondContact O-CA 3.09Å; I497-F500 WeakPolarHBondContact O-CB 3.25Å; I497-F500 PolarHBondContact O-N 3.21Å; I497-F500 VanDerWaalsContact O-N 3.12Å; I497-L501 HydrophobicContact CG2-CD1 4.05Å; I497-L501 HydrophobicContact CG2-CG 4.43Å; I497-L501 WeakPolarHBondContact O-CG 3.29Å; I497-L501 PolarHBondContact O-N 2.95Å
498	N	70.8	Confident	68.9	Low	4 Å²	4	46.4 Å²	46.4	2%	0.021	27%	0.272	C	S	.	.	H	α-helix	trans	-69.8	-34.1	-178.6	-70	-24	0	0	0	111.6	S443 V444 V494 V495 F500 G502	S443-N498 PolarHBondContact O-ND2 3.16Å; S443-N498 PolarHBondContact OG-ND2 2.97Å; S443-N498 PolarHBondContact OG-OD1 3.36Å; S443-N498 VanDerWaalsContact OG-OD1 3.12Å; V444-N498 WeakPolarHBondContact CA-ND2 3.49Å; V444-N498 HydrophobicContact CG2-CB 3.86Å; V444-N498 VanDerWaalsContact CG2-CG 3.44Å; V444-N498 PolarHBondContact N-ND2 3.31Å; V494-N498 WeakPolarHBondContact CG1-ND2 3.01Å; V494-N498 WeakPolarHBondContact O-CB 3.2Å; V494-N498 PolarHBondContact O-N 3.01Å; V494-N498 PolarHBondContact O-ND2 3.36Å; V495-N498 PolarHBondContact O-N 3.44Å; N498-F500 VanDerWaalsContact C-N 3.31Å; N498-G502 PolarHBondContact O-N 3.5Å
499	L	70.4	Confident	68.9	Low	68 Å²	68	51.4 Å²	51.4	36%	0.356	29%	0.287	S	S	.	.	H	α-helix	trans	-63.4	-41.1	169.5	-72.1	171.7	0	0	0	110.7	V495 I497 S503 F524 L528	V495-L499 HydrophobicContact CG1-CD1 3.87Å; V495-L499 HydrophobicContact CG1-CG 4.24Å; V495-L499 WeakPolarHBondContact O-CB 3.5Å; V495-L499 WeakPolarHBondContact O-CG 3.27Å; V495-L499 PolarHBondContact O-N 3.06Å; I497-L499 VanDerWaalsContact C-N 3.34Å; I497-L499 PolarHBondContact O-N 2.87Å; L499-S503 PolarHBondContact O-N 3.02Å; L499-F524 HydrophobicContact CD2-CD1 3.84Å; L499-F524 HydrophobicContact CD2-CE1 4.32Å; L499-L528 HydrophobicContact CD1-CD1 4.46Å; L499-L528 HydrophobicContact CD1-CD2 4.43Å; L499-L528 HydrophobicContact CD2-CD1 4.06Å; L499-L528 HydrophobicContact CD2-CD2 4.46Å; L499-L528 HydrophobicContact CD2-CG 4.49Å
500	F	71.8	Confident	68.7	Low	73 Å²	73	48.5 Å²	48.5	32%	0.32	27%	0.272	S	S	.	.	H	α-helix	trans	-65	-53	176.3	179.2	-96.7	0	0	0	111.9	W244 L247 S496 I497 N498 G502 S503 V504	W244-F500 HydrophobicContact CE3-CE1 4.05Å; W244-F500 AromaticContact CE3-CZ 3.86Å; W244-F500 HydrophobicContact CE3-CZ 3.86Å; W244-F500 HydrophobicContact CH2-CE1 4.34Å; W244-F500 AromaticContact CH2-CE2 3.96Å; W244-F500 HydrophobicContact CH2-CE2 3.96Å; W244-F500 AromaticContact CH2-CZ 3.43Å; W244-F500 HydrophobicContact CH2-CZ 3.43Å; W244-F500 VanDerWaalsContact CH2-CZ 3.43Å; W244-F500 AromaticContact CZ3-CE1 3.49Å; W244-F500 HydrophobicContact CZ3-CE1 3.49Å; W244-F500 VanDerWaalsContact CZ3-CE1 3.49Å; W244-F500 AromaticContact CZ3-CE2 3.92Å; W244-F500 HydrophobicContact CZ3-CE2 3.92Å; W244-F500 AromaticContact CZ3-CZ 3Å; W244-F500 HydrophobicContact CZ3-CZ 3Å; L247-F500 HydrophobicContact CD2-CE1 4.44Å; S496-F500 WeakPolarHBondContact O-CB 3.47Å; S496-F500 PolarHBondContact O-N 2.7Å; I497-F500 CarbonylContact O-C 3.6Å; I497-F500 WeakPolarHBondContact O-CA 3.09Å; I497-F500 WeakPolarHBondContact O-CB 3.25Å; I497-F500 PolarHBondContact O-N 3.21Å; I497-F500 VanDerWaalsContact O-N 3.12Å; N498-F500 VanDerWaalsContact C-N 3.31Å; F500-G502 VanDerWaalsContact C-N 3.33Å; F500-G502 PolarHBondContact O-N 3.23Å; F500-S503 WeakPolarHBondContact O-CA 3.41Å; F500-S503 WeakPolarHBondContact O-CB 3.12Å; F500-S503 PolarHBondContact O-N 3.27Å; F500-S503 PolarHBondContact O-OG 3.35Å; F500-V504 HydrophobicContact CD1-CG2 4.26Å; F500-V504 HydrophobicContact CE1-CG2 3.56Å; F500-V504 HydrophobicContact CE2-CG2 4.16Å; F500-V504 HydrophobicContact CZ-CG2 3.45Å; F500-V504 VanDerWaalsContact CZ-CG2 3.45Å; F500-V504 WeakPolarHBondContact O-CG2 3.47Å; F500-V504 PolarHBondContact O-N 3.45Å
501	L	67	Low	69	Low	11 Å²	11	51.6 Å²	51.6	6%	0.058	29%	0.293	C	S	.	.	H	α-helix	trans	-60.3	-41.7	177.2	-73	177.1	0	0	0	112	E248 V251 V440 I497 S503 V504 V505	E248-L501 HydrophobicContact CG-CD2 4.24Å; V251-L501 HydrophobicContact CB-CD1 3.92Å; V251-L501 HydrophobicContact CG1-CD1 3.52Å; V251-L501 HydrophobicContact CG2-CD1 4.09Å; V440-L501 HydrophobicContact CB-CD1 4.32Å; V440-L501 HydrophobicContact CG1-CB 4.42Å; V440-L501 HydrophobicContact CG1-CD1 3.58Å; V440-L501 HydrophobicContact CG2-CD1 3.77Å; I497-L501 HydrophobicContact CG2-CD1 4.05Å; I497-L501 HydrophobicContact CG2-CG 4.43Å; I497-L501 WeakPolarHBondContact O-CG 3.29Å; I497-L501 PolarHBondContact O-N 2.95Å; L501-S503 VanDerWaalsContact C-N 3.28Å; L501-S503 PolarHBondContact O-N 2.97Å; L501-V504 PolarHBondContact O-N 2.94Å; L501-V504 VanDerWaalsContact O-N 3.09Å; L501-V505 WeakPolarHBondContact O-CB 3.4Å; L501-V505 WeakPolarHBondContact O-CG2 3.41Å; L501-V505 PolarHBondContact O-N 3.1Å
502	G	67.4	Low	69.4	Low	10 Å²	10	58.2 Å²	58.2	10%	0.103	32%	0.323	C	S	.	.	H	α-helix	trans	-53.1	-47.9	171	0	0	0	0	0	111.4	N498 F500 V504 I506	N498-G502 PolarHBondContact O-N 3.5Å; F500-G502 VanDerWaalsContact C-N 3.33Å; F500-G502 PolarHBondContact O-N 3.23Å; G502-V504 VanDerWaalsContact C-N 3.31Å; G502-V504 PolarHBondContact O-N 3.35Å; G502-I506 VanDerWaalsContact O-CB 3.29Å; G502-I506 WeakPolarHBondContact O-CB 3.25Å; G502-I506 VanDerWaalsContact O-CD1 3.26Å; G502-I506 WeakPolarHBondContact O-CD1 3.25Å; G502-I506 WeakPolarHBondContact O-CG1 3.25Å; G502-I506 PolarHBondContact O-N 2.88Å
503	S	67.5	Low	69.8	Low	47 Å²	47	59.5 Å²	59.5	33%	0.329	32%	0.323	S	S	.	.	H	α-helix	trans	-63.8	-34.7	177.8	83.9	0	0	0	0	113.4	L499 F500 L501 K507	L499-S503 PolarHBondContact O-N 3.02Å; F500-S503 WeakPolarHBondContact O-CA 3.41Å; F500-S503 WeakPolarHBondContact O-CB 3.12Å; F500-S503 PolarHBondContact O-N 3.27Å; F500-S503 PolarHBondContact O-OG 3.35Å; L501-S503 VanDerWaalsContact C-N 3.28Å; L501-S503 PolarHBondContact O-N 2.97Å; S503-K507 WeakPolarHBondContact O-CB 3.06Å; S503-K507 VanDerWaalsContact O-CG 3.29Å; S503-K507 WeakPolarHBondContact O-CG 3.43Å; S503-K507 PolarHBondContact O-N 3.45Å; S503-K507 VanDerWaalsContact O-N 3.16Å
504	V	67.3	Low	70.4	Confident	54 Å²	54	67.1 Å²	67.1	33%	0.327	34%	0.343	S	S	.	.	H	α-helix	trans	-71.9	-51.1	177.7	174.6	0	0	0	0	110.6	F500 L501 G502 I506 K507 A508	F500-V504 HydrophobicContact CD1-CG2 4.26Å; F500-V504 HydrophobicContact CE1-CG2 3.56Å; F500-V504 HydrophobicContact CE2-CG2 4.16Å; F500-V504 HydrophobicContact CZ-CG2 3.45Å; F500-V504 VanDerWaalsContact CZ-CG2 3.45Å; F500-V504 WeakPolarHBondContact O-CG2 3.47Å; F500-V504 PolarHBondContact O-N 3.45Å; L501-V504 PolarHBondContact O-N 2.94Å; L501-V504 VanDerWaalsContact O-N 3.09Å; G502-V504 VanDerWaalsContact C-N 3.31Å; G502-V504 PolarHBondContact O-N 3.35Å; V504-I506 VanDerWaalsContact C-N 3.29Å; V504-I506 PolarHBondContact O-N 3.05Å; V504-K507 PolarHBondContact O-N 3.12Å; V504-A508 VanDerWaalsContact O-CB 3.28Å; V504-A508 WeakPolarHBondContact O-CB 3.48Å; V504-A508 PolarHBondContact O-N 3.36Å
505	V	65.6	Low	71.1	Confident	39 Å²	39	69.7 Å²	69.7	24%	0.236	36%	0.364	C	S	.	.	H	α-helix	trans	-59.4	-42.2	178.6	173.1	0	0	0	0	110.7	L501 K507 A508 R509	L501-V505 WeakPolarHBondContact O-CB 3.4Å; L501-V505 WeakPolarHBondContact O-CG2 3.41Å; L501-V505 PolarHBondContact O-N 3.1Å; V505-K507 VanDerWaalsContact C-N 3.3Å; V505-K507 PolarHBondContact O-N 2.87Å; V505-A508 PolarHBondContact O-N 3.33Å; V505-R509 HydrophobicContact CG1-CB 4.41Å; V505-R509 WeakPolarHBondContact O-CB 3.27Å; V505-R509 PolarHBondContact O-N 2.92Å
506	I	66.9	Low	71.6	Confident	17 Å²	17	70.8 Å²	70.8	9%	0.087	37%	0.371	C	S	.	.	H	α-helix	trans	-63.1	-37.6	176.4	-65.9	165.4	0	0	0	111.2	G502 V504 L510 Y517 M520 F524	G502-I506 VanDerWaalsContact O-CB 3.29Å; G502-I506 WeakPolarHBondContact O-CB 3.25Å; G502-I506 VanDerWaalsContact O-CD1 3.26Å; G502-I506 WeakPolarHBondContact O-CD1 3.25Å; G502-I506 WeakPolarHBondContact O-CG1 3.25Å; G502-I506 PolarHBondContact O-N 2.88Å; V504-I506 VanDerWaalsContact C-N 3.29Å; V504-I506 PolarHBondContact O-N 3.05Å; I506-L510 HydrophobicContact CB-CD1 4.2Å; I506-L510 HydrophobicContact CG1-CD1 3.86Å; I506-L510 HydrophobicContact CG2-CD1 4.24Å; I506-Y517 HydrophobicContact CG2-CD1 3.33Å; I506-Y517 HydrophobicContact CG2-CE1 3.19Å; I506-Y517 HydrophobicContact CG2-CG 4.35Å; I506-M520 HydrophobicContact CD1-CB 3.65Å; I506-M520 HydrophobicContact CD1-CE 4.11Å; I506-M520 HydrophobicContact CD1-CG 4.08Å; I506-M520 HydrophobicContact CG1-CB 4.19Å; I506-M520 HydrophobicContact CG1-CE 4.07Å; I506-M520 HydrophobicContact CG1-CG 4.05Å; I506-F524 HydrophobicContact CD1-CD2 4.47Å; I506-F524 HydrophobicContact CD1-CE2 3.96Å
507	K	66.6	Low	72	Confident	144 Å²	144	71.7 Å²	71.7	63%	0.626	36%	0.364	S	S	*	.	H	α-helix	trans	-77.3	-34.9	178.8	-76.6	177.4	-179.6	179.9	0	113.3	S503 V504 V505	S503-K507 WeakPolarHBondContact O-CB 3.06Å; S503-K507 VanDerWaalsContact O-CG 3.29Å; S503-K507 WeakPolarHBondContact O-CG 3.43Å; S503-K507 PolarHBondContact O-N 3.45Å; S503-K507 VanDerWaalsContact O-N 3.16Å; V504-K507 PolarHBondContact O-N 3.12Å; V505-K507 VanDerWaalsContact C-N 3.3Å; V505-K507 PolarHBondContact O-N 2.87Å
508	A	65.9	Low	72.8	Confident	79 Å²	79	74.3 Å²	74.3	65%	0.653	38%	0.378	S	S	*	.	H	α-helix	trans	-92.6	-36.4	-171	0	0	0	0	0	113.6	V504 V505	V504-A508 VanDerWaalsContact O-CB 3.28Å; V504-A508 WeakPolarHBondContact O-CB 3.48Å; V504-A508 PolarHBondContact O-N 3.36Å; V505-A508 PolarHBondContact O-N 3.33Å
509	R	65.8	Low	73.4	Confident	143 Å²	143	75.5 Å²	75.5	54%	0.54	39%	0.392	S	S	.	.	T	Hydrogen-bonded Turn	trans	-114.7	-20.1	-169.8	-64.3	-171.3	-178.7	156.9	3	114.5	V505	V505-R509 HydrophobicContact CG1-CB 4.41Å; V505-R509 WeakPolarHBondContact O-CB 3.27Å; V505-R509 PolarHBondContact O-N 2.92Å
510	L	68.7	Low	73.9	Confident	53 Å²	53	74.7 Å²	74.7	28%	0.277	39%	0.387	S	S	.	.	S	Bend	trans	-94.6	139.7	179.7	-68.9	173.8	0	0	0	111.1	I506 V516 M520	I506-L510 HydrophobicContact CB-CD1 4.2Å; I506-L510 HydrophobicContact CG1-CD1 3.86Å; I506-L510 HydrophobicContact CG2-CD1 4.24Å; L510-V516 HydrophobicContact CB-CG1 3.87Å; L510-V516 HydrophobicContact CD1-CG1 3.54Å; L510-V516 HydrophobicContact CD2-CG1 4.04Å; L510-V516 HydrophobicContact CG-CG1 4.02Å; L510-M520 HydrophobicContact CD1-CG 3.88Å; L510-M520 HydrophobicContact CD1-SD 4.35Å
511	P	74.2	Confident	74.5	Confident	72 Å²	72	73.2 Å²	73.2	47%	0.468	39%	0.392	S	S	.	.			trans	-60.8	142.8	176.4	26.4	-33.5	0	0	0	109.8	H513 V516	P511-H513 PolarHBondContact O-N 3.21Å; P511-V516 HydrophobicContact CG-CG2 4.48Å
512	H	74.5	Confident	75.5	Confident	146 Å²	146	77.8 Å²	77.8	68%	0.676	42%	0.416	S	S	*	.	S	Bend	trans	-70.4	65.9	-178.5	-64.4	-49.6	0	0	0	112.4	Y517	H512-Y517 PolarHBondContact ND1-OH 3.19Å
513	H	80.8	Confident	76.4	Confident	118 Å²	118	82.7 Å²	82.7	55%	0.546	44%	0.439	S	S	.	.			trans	-117.3	125.3	175.9	-71.6	-58.4	0	0	0	109.7	P511 A515 V516 Y517	P511-H513 PolarHBondContact O-N 3.21Å; H513-A515 PolarHBondContact O-N 3.46Å; H513-A515 VanDerWaalsContact O-N 3.08Å; H513-V516 HydrophobicContact CB-CG2 4.11Å; H513-V516 WeakPolarHBondContact O-CB 3.11Å; H513-V516 PolarHBondContact O-N 3.25Å; H513-Y517 VanDerWaalsContact O-CD2 3.29Å; H513-Y517 WeakPolarHBondContact O-CD2 3.43Å; H513-Y517 PolarHBondContact O-N 3.07Å
514	W	83.3	Confident	77.1	Confident	201 Å²	201	82.6 Å²	82.6	76%	0.761	43%	0.433	S	S	*	.	H	α-helix	trans	-52.8	-33.6	-178.9	66.8	-92.9	0	0	0	113.1	V516 Y517 L518	W514-V516 VanDerWaalsContact C-N 3.31Å; W514-V516 PolarHBondContact O-N 2.62Å; W514-Y517 PolarHBondContact O-N 2.96Å; W514-L518 HydrophobicContact CZ3-CD1 4.33Å; W514-L518 WeakPolarHBondContact O-CB 3.34Å; W514-L518 PolarHBondContact O-N 2.97Å
515	A	84.9	Confident	78.1	Confident	53 Å²	53	82.9 Å²	82.9	44%	0.438	44%	0.441	S	S	.	.	H	α-helix	trans	-63.8	-35.7	178	0	0	0	0	0	112.4	H513 L518 G519	H513-A515 PolarHBondContact O-N 3.46Å; H513-A515 VanDerWaalsContact O-N 3.08Å; A515-L518 PolarHBondContact O-N 2.94Å; A515-G519 PolarHBondContact O-N 3.14Å
516	V	80.4	Confident	79.3	Confident	43 Å²	43	85.3 Å²	85.3	26%	0.261	46%	0.459	S	S	.	.	H	α-helix	trans	-69.9	-44.5	176.6	-179.3	0	0	0	0	110.2	L510 P511 H513 W514 L518 G519 M520	L510-V516 HydrophobicContact CB-CG1 3.87Å; L510-V516 HydrophobicContact CD1-CG1 3.54Å; L510-V516 HydrophobicContact CD2-CG1 4.04Å; L510-V516 HydrophobicContact CG-CG1 4.02Å; P511-V516 HydrophobicContact CG-CG2 4.48Å; H513-V516 HydrophobicContact CB-CG2 4.11Å; H513-V516 WeakPolarHBondContact O-CB 3.11Å; H513-V516 PolarHBondContact O-N 3.25Å; W514-V516 VanDerWaalsContact C-N 3.31Å; W514-V516 PolarHBondContact O-N 2.62Å; V516-L518 VanDerWaalsContact C-N 3.32Å; V516-L518 PolarHBondContact O-N 2.76Å; V516-G519 PolarHBondContact O-N 3.49Å; V516-M520 HydrophobicContact CG1-CG 4.46Å; V516-M520 WeakPolarHBondContact O-CB 3.21Å; V516-M520 VanDerWaalsContact O-CG 3.31Å; V516-M520 WeakPolarHBondContact O-CG 2.85Å; V516-M520 PolarHBondContact O-N 3.48Å
517	Y	82.1	Confident	80.3	Confident	85 Å²	85	85.8 Å²	85.8	33%	0.333	46%	0.459	S	S	.	.	H	α-helix	trans	-59.7	-42.5	173.7	-69.7	-78.2	0	0	0	112.1	I506 H512 H513 W514 G521	I506-Y517 HydrophobicContact CG2-CD1 3.33Å; I506-Y517 HydrophobicContact CG2-CE1 3.19Å; I506-Y517 HydrophobicContact CG2-CG 4.35Å; H512-Y517 PolarHBondContact ND1-OH 3.19Å; H513-Y517 VanDerWaalsContact O-CD2 3.29Å; H513-Y517 WeakPolarHBondContact O-CD2 3.43Å; H513-Y517 PolarHBondContact O-N 3.07Å; W514-Y517 PolarHBondContact O-N 2.96Å; Y517-G521 PolarHBondContact O-N 3.26Å
518	L	86.1	Confident	81.3	Confident	100 Å²	100	82 Å²	82	52%	0.524	45%	0.445	S	S	.	.	H	α-helix	trans	-65.8	-45.6	178.4	-175.8	141.5	0	0	0	111.6	W514 A515 V516 G521 L522	W514-L518 HydrophobicContact CZ3-CD1 4.33Å; W514-L518 WeakPolarHBondContact O-CB 3.34Å; W514-L518 PolarHBondContact O-N 2.97Å; A515-L518 PolarHBondContact O-N 2.94Å; V516-L518 VanDerWaalsContact C-N 3.32Å; V516-L518 PolarHBondContact O-N 2.76Å; L518-G521 PolarHBondContact O-N 2.93Å; L518-L522 HydrophobicContact CD2-CD1 3.75Å; L518-L522 WeakPolarHBondContact O-CG 3.16Å; L518-L522 PolarHBondContact O-N 3.04Å
519	G	84.4	Confident	82.5	Confident	30 Å²	30	80.1 Å²	80.1	31%	0.309	43%	0.434	S	S	.	.	H	α-helix	trans	-60.3	-46.4	176.2	0	0	0	0	0	112.5	A515 V516 L522 L523	A515-G519 PolarHBondContact O-N 3.14Å; V516-G519 PolarHBondContact O-N 3.49Å; G519-L522 PolarHBondContact O-N 2.94Å; G519-L523 WeakPolarHBondContact O-CG 3.3Å; G519-L523 PolarHBondContact O-N 2.94Å
520	M	80.6	Confident	83.7	Confident	51 Å²	51	74.5 Å²	74.5	25%	0.251	41%	0.414	S	S	.	.	H	α-helix	trans	-64.9	-41.1	176.2	-69.9	-61.3	-62.2	0	0	112	I506 L510 V516 L522 L523 F524	I506-M520 HydrophobicContact CD1-CB 3.65Å; I506-M520 HydrophobicContact CD1-CE 4.11Å; I506-M520 HydrophobicContact CD1-CG 4.08Å; I506-M520 HydrophobicContact CG1-CB 4.19Å; I506-M520 HydrophobicContact CG1-CE 4.07Å; I506-M520 HydrophobicContact CG1-CG 4.05Å; L510-M520 HydrophobicContact CD1-CG 3.88Å; L510-M520 HydrophobicContact CD1-SD 4.35Å; V516-M520 HydrophobicContact CG1-CG 4.46Å; V516-M520 WeakPolarHBondContact O-CB 3.21Å; V516-M520 VanDerWaalsContact O-CG 3.31Å; V516-M520 WeakPolarHBondContact O-CG 2.85Å; V516-M520 PolarHBondContact O-N 3.48Å; M520-L522 VanDerWaalsContact C-N 3.32Å; M520-L522 PolarHBondContact O-N 2.54Å; M520-L523 PolarHBondContact O-N 2.99Å; M520-L523 HydrophobicContact SD-CD1 4.21Å; M520-F524 HydrophobicContact CE-CD2 4.47Å; M520-F524 HydrophobicContact CE-CE2 3.8Å; M520-F524 VanDerWaalsContact O-CD2 3.23Å; M520-F524 WeakPolarHBondContact O-CD2 3.47Å; M520-F524 PolarHBondContact O-N 3.31Å
521	G	83.7	Confident	84.6	Confident	41 Å²	41	72.4 Å²	72.4	42%	0.423	40%	0.403	S	S	.	.	H	α-helix	trans	-59.1	-41.9	175.5	0	0	0	0	0	112.6	Y517 L518 F524 A525	Y517-G521 PolarHBondContact O-N 3.26Å; L518-G521 PolarHBondContact O-N 2.93Å; G521-F524 PolarHBondContact O-N 3.37Å; G521-A525 WeakPolarHBondContact O-CB 3.29Å; G521-A525 PolarHBondContact O-N 3.28Å
522	L	88.2	Confident	85.2	Confident	107 Å²	107	75.7 Å²	75.7	56%	0.56	41%	0.41	S	S	*	.	H	α-helix	trans	-64.2	-44.8	174.4	-73	171.6	0	0	0	112	L518 G519 M520 F524 A525 C526	L518-L522 HydrophobicContact CD2-CD1 3.75Å; L518-L522 WeakPolarHBondContact O-CG 3.16Å; L518-L522 PolarHBondContact O-N 3.04Å; G519-L522 PolarHBondContact O-N 2.94Å; M520-L522 VanDerWaalsContact C-N 3.32Å; M520-L522 PolarHBondContact O-N 2.54Å; L522-F524 PolarHBondContact O-N 3.09Å; L522-A525 PolarHBondContact O-N 3.07Å; L522-C526 PolarHBondContact O-N 3.39Å; L522-C526 PolarHBondContact O-SG 3.04Å; L522-C526 VanDerWaalsContact O-SG 3.34Å
523	L	85.9	Confident	86	Confident	113 Å²	113	72.5 Å²	72.5	59%	0.592	39%	0.393	S	S	*	.	H	α-helix	trans	-59.8	-45.1	176.2	-73	173.9	0	0	0	111.8	G519 M520 C526 Y527	G519-L523 WeakPolarHBondContact O-CG 3.3Å; G519-L523 PolarHBondContact O-N 2.94Å; M520-L523 PolarHBondContact O-N 2.99Å; M520-L523 HydrophobicContact SD-CD1 4.21Å; L523-C526 PolarHBondContact O-N 2.99Å; L523-Y527 WeakPolarHBondContact O-CB 3.48Å; L523-Y527 PolarHBondContact O-N 3.32Å
524	F	83.1	Confident	86.4	Confident	46 Å²	46	66.9 Å²	66.9	20%	0.202	37%	0.367	C	S	.	.	H	α-helix	trans	-62.9	-41.8	175.5	-86.2	-67.9	0	0	0	112.3	L499 I506 M520 G521 L522 Y527 L528	L499-F524 HydrophobicContact CD2-CD1 3.84Å; L499-F524 HydrophobicContact CD2-CE1 4.32Å; I506-F524 HydrophobicContact CD1-CD2 4.47Å; I506-F524 HydrophobicContact CD1-CE2 3.96Å; M520-F524 HydrophobicContact CE-CD2 4.47Å; M520-F524 HydrophobicContact CE-CE2 3.8Å; M520-F524 VanDerWaalsContact O-CD2 3.23Å; M520-F524 WeakPolarHBondContact O-CD2 3.47Å; M520-F524 PolarHBondContact O-N 3.31Å; G521-F524 PolarHBondContact O-N 3.37Å; L522-F524 PolarHBondContact O-N 3.09Å; F524-Y527 PolarHBondContact O-N 3.44Å; F524-L528 WeakPolarHBondContact O-CB 3.38Å; F524-L528 WeakPolarHBondContact O-CG 3.46Å; F524-L528 PolarHBondContact O-N 3.29Å
525	A	87.9	Confident	86.5	Confident	60 Å²	60	60 Å²	60	50%	0.496	34%	0.344	S	S	.	.	H	α-helix	trans	-63	-41.8	176.1	0	0	0	0	0	111.9	G521 L522 G529	G521-A525 WeakPolarHBondContact O-CB 3.29Å; G521-A525 PolarHBondContact O-N 3.28Å; L522-A525 PolarHBondContact O-N 3.07Å; A525-G529 PolarHBondContact O-N 3.01Å
526	C	91.1	Very high	86.7	Confident	90 Å²	90	64.3 Å²	64.3	61%	0.608	35%	0.349	S	S	*	.	H	α-helix	trans	-62.9	-44.9	174	-71.2	0	0	0	0	111.9	L522 L523 G529 F530	L522-C526 PolarHBondContact O-N 3.39Å; L522-C526 PolarHBondContact O-SG 3.04Å; L522-C526 VanDerWaalsContact O-SG 3.34Å; L523-C526 PolarHBondContact O-N 2.99Å; C526-G529 PolarHBondContact O-N 3.02Å; C526-F530 WeakPolarHBondContact O-CB 3.4Å; C526-F530 PolarHBondContact O-N 3.43Å
527	Y	88.5	Confident	87.1	Confident	27 Å²	27	64 Å²	64	11%	0.106	35%	0.345	C	S	.	.	H	α-helix	trans	-58	-53.5	175.9	169.1	-92.2	0	0	0	111.3	V444 F448 V495 L523 F524 G529 F530 V531	V444-Y527 HydrophobicContact CG1-CD2 4.13Å; V444-Y527 HydrophobicContact CG1-CE2 3.57Å; V444-Y527 WeakPolarHBondContact O-CE2 3.36Å; V444-Y527 PolarHBondContact O-OH 3.43Å; V444-Y527 VanDerWaalsContact O-OH 3.1Å; F448-Y527 HydrophobicContact CE1-CE2 4.46Å; F448-Y527 AromaticContact CE2-CD2 3.89Å; F448-Y527 HydrophobicContact CE2-CD2 3.89Å; F448-Y527 AromaticContact CE2-CE2 3.53Å; F448-Y527 HydrophobicContact CE2-CE2 3.53Å; F448-Y527 AromaticContact CZ-CD2 3.49Å; F448-Y527 HydrophobicContact CZ-CD2 3.49Å; F448-Y527 VanDerWaalsContact CZ-CD2 3.49Å; F448-Y527 AromaticContact CZ-CE2 3.39Å; F448-Y527 HydrophobicContact CZ-CE2 3.39Å; V495-Y527 HydrophobicContact CG2-CE1 4.32Å; L523-Y527 WeakPolarHBondContact O-CB 3.48Å; L523-Y527 PolarHBondContact O-N 3.32Å; F524-Y527 PolarHBondContact O-N 3.44Å; Y527-G529 PolarHBondContact O-N 3.4Å; Y527-F530 PolarHBondContact O-N 3.16Å; Y527-V531 HydrophobicContact CE1-CG2 4.14Å; Y527-V531 HydrophobicContact CE2-CG2 4.21Å; Y527-V531 WeakPolarHBondContact O-CG2 3.43Å; Y527-V531 PolarHBondContact O-N 2.91Å
528	L	87	Confident	87.2	Confident	63 Å²	63	60 Å²	60	33%	0.33	33%	0.329	S	S	.	.	H	α-helix	trans	-63.3	-40.9	179.4	-69.8	179.4	0	0	0	112.1	V495 L499 F524 F530 V531 F532	V495-L528 HydrophobicContact CG1-CD2 3.52Å; L499-L528 HydrophobicContact CD1-CD1 4.46Å; L499-L528 HydrophobicContact CD1-CD2 4.43Å; L499-L528 HydrophobicContact CD2-CD1 4.06Å; L499-L528 HydrophobicContact CD2-CD2 4.46Å; L499-L528 HydrophobicContact CD2-CG 4.49Å; F524-L528 WeakPolarHBondContact O-CB 3.38Å; F524-L528 WeakPolarHBondContact O-CG 3.46Å; F524-L528 PolarHBondContact O-N 3.29Å; L528-F530 VanDerWaalsContact C-N 3.32Å; L528-F530 PolarHBondContact O-N 3.02Å; L528-V531 PolarHBondContact O-N 2.72Å; L528-F532 WeakPolarHBondContact O-CB 3.45Å; L528-F532 PolarHBondContact O-N 2.97Å
529	G	90.9	Very high	87.1	Confident	41 Å²	41	58.1 Å²	58.1	42%	0.423	32%	0.317	S	S	.	.	H	α-helix	trans	-61.1	-40.3	176.2	0	0	0	0	0	112.2	A525 C526 Y527 Y533	A525-G529 PolarHBondContact O-N 3.01Å; C526-G529 PolarHBondContact O-N 3.02Å; Y527-G529 PolarHBondContact O-N 3.4Å; G529-Y533 WeakPolarHBondContact O-CB 3.32Å; G529-Y533 PolarHBondContact O-N 3.13Å
530	F	91.4	Very high	87.1	Confident	25 Å²	25	59.5 Å²	59.5	11%	0.11	32%	0.316	C	S	.	.	H	α-helix	trans	-71.9	-41.2	177.1	-170.8	-124.1	0	0	0	112.6	A139 I142 L143 F448 C526 Y527 L528 F532 Y533 L534	A139-F530 HydrophobicContact CB-CE2 4.28Å; I142-F530 HydrophobicContact CB-CE1 4.08Å; I142-F530 HydrophobicContact CB-CE2 4.14Å; I142-F530 HydrophobicContact CB-CZ 3.71Å; I142-F530 HydrophobicContact CD1-CE2 4.24Å; I142-F530 HydrophobicContact CG2-CD1 3.76Å; I142-F530 HydrophobicContact CG2-CD2 4.36Å; I142-F530 HydrophobicContact CG2-CE1 3.39Å; I142-F530 HydrophobicContact CG2-CE2 4.03Å; I142-F530 HydrophobicContact CG2-CG 4.24Å; I142-F530 HydrophobicContact CG2-CZ 3.54Å; L143-F530 HydrophobicContact CD2-CE1 4.06Å; L143-F530 HydrophobicContact CD2-CZ 4.26Å; L143-F530 HydrophobicContact CG-CE1 4.21Å; L143-F530 HydrophobicContact CG-CZ 3.95Å; F448-F530 AromaticContact CD1-CD1 3.96Å; F448-F530 HydrophobicContact CD1-CD1 3.96Å; F448-F530 AromaticContact CD1-CE1 3.97Å; F448-F530 HydrophobicContact CD1-CE1 3.97Å; F448-F530 AromaticContact CE1-CD1 3.42Å; F448-F530 HydrophobicContact CE1-CD1 3.42Å; F448-F530 VanDerWaalsContact CE1-CD1 3.42Å; F448-F530 AromaticContact CE1-CE1 3.91Å; F448-F530 HydrophobicContact CE1-CE1 3.91Å; F448-F530 HydrophobicContact CE1-CG 4.48Å; F448-F530 HydrophobicContact CZ-CD1 4.19Å; C526-F530 WeakPolarHBondContact O-CB 3.4Å; C526-F530 PolarHBondContact O-N 3.43Å; Y527-F530 PolarHBondContact O-N 3.16Å; L528-F530 VanDerWaalsContact C-N 3.32Å; L528-F530 PolarHBondContact O-N 3.02Å; F530-F532 VanDerWaalsContact C-N 3.33Å; F530-F532 PolarHBondContact O-N 3.4Å; F530-Y533 HydrophobicContact CD2-CD1 4.15Å; F530-Y533 HydrophobicContact CE2-CD1 4.02Å; F530-Y533 HydrophobicContact CE2-CE1 4.48Å; F530-Y533 WeakPolarHBondContact O-CB 3.25Å; F530-Y533 PolarHBondContact O-N 3.45Å; F530-L534 HydrophobicContact CD1-CD1 4.24Å; F530-L534 HydrophobicContact CE1-CD1 3.89Å; F530-L534 HydrophobicContact CE1-CG 4.36Å; F530-L534 HydrophobicContact CE2-CD2 4.34Å; F530-L534 HydrophobicContact CE2-CG 4.43Å; F530-L534 HydrophobicContact CZ-CD1 4.2Å; F530-L534 HydrophobicContact CZ-CD2 4.09Å; F530-L534 HydrophobicContact CZ-CG 4.24Å; F530-L534 WeakPolarHBondContact O-CG 3.25Å; F530-L534 PolarHBondContact O-N 2.83Å
531	V	86.9	Confident	87.3	Confident	9 Å²	9	58.3 Å²	58.3	6%	0.055	31%	0.31	C	S	.	.	H	α-helix	trans	-58.5	-46.2	172	171.3	0	0	0	0	110.6	P447 F448 I451 Y527 L528 Y533 L534 I535	P447-V531 HydrophobicContact CB-CG2 4.3Å; F448-V531 HydrophobicContact CE1-CG2 3.72Å; F448-V531 HydrophobicContact CZ-CG2 4.07Å; I451-V531 HydrophobicContact CD1-CG1 3.95Å; Y527-V531 HydrophobicContact CE1-CG2 4.14Å; Y527-V531 HydrophobicContact CE2-CG2 4.21Å; Y527-V531 WeakPolarHBondContact O-CG2 3.43Å; Y527-V531 PolarHBondContact O-N 2.91Å; L528-V531 PolarHBondContact O-N 2.72Å; V531-Y533 VanDerWaalsContact C-N 3.34Å; V531-Y533 PolarHBondContact O-N 3.02Å; V531-L534 PolarHBondContact O-N 3.41Å; V531-I535 HydrophobicContact CG1-CD1 3.99Å; V531-I535 WeakPolarHBondContact O-CG1 3.43Å; V531-I535 PolarHBondContact O-N 2.82Å
532	F	87.9	Confident	87.2	Confident	140 Å²	140	56.5 Å²	56.5	61%	0.614	29%	0.291	S	S	*	.	H	α-helix	trans	-60.5	-43.3	176	-178.6	-96.3	0	0	0	111.9	L528 F530 L534 I535 W536	L528-F532 WeakPolarHBondContact O-CB 3.45Å; L528-F532 PolarHBondContact O-N 2.97Å; F530-F532 VanDerWaalsContact C-N 3.33Å; F530-F532 PolarHBondContact O-N 3.4Å; F532-L534 VanDerWaalsContact C-N 3.34Å; F532-L534 PolarHBondContact O-N 3.49Å; F532-I535 PolarHBondContact O-N 2.71Å; F532-W536 VanDerWaalsContact O-CB 3.26Å; F532-W536 WeakPolarHBondContact O-CB 3.23Å; F532-W536 PolarHBondContact O-N 3.03Å
533	Y	91.9	Very high	86.7	Confident	80 Å²	80	56.1 Å²	56.1	31%	0.314	28%	0.282	S	S	.	.	H	α-helix	trans	-57.6	-44.2	174.8	169.5	-91.3	0	0	0	112.2	P136 A139 G529 F530 V531 W536 F537	P136-Y533 VanDerWaalsContact CG-OH 3.24Å; P136-Y533 WeakPolarHBondContact CG-OH 3.31Å; A139-Y533 HydrophobicContact CB-CD1 4.49Å; A139-Y533 HydrophobicContact CB-CE1 3.52Å; G529-Y533 WeakPolarHBondContact O-CB 3.32Å; G529-Y533 PolarHBondContact O-N 3.13Å; F530-Y533 HydrophobicContact CD2-CD1 4.15Å; F530-Y533 HydrophobicContact CE2-CD1 4.02Å; F530-Y533 HydrophobicContact CE2-CE1 4.48Å; F530-Y533 WeakPolarHBondContact O-CB 3.25Å; F530-Y533 PolarHBondContact O-N 3.45Å; V531-Y533 VanDerWaalsContact C-N 3.34Å; V531-Y533 PolarHBondContact O-N 3.02Å; Y533-W536 PolarHBondContact O-N 2.84Å; Y533-F537 VanDerWaalsContact O-CB 3.27Å; Y533-F537 WeakPolarHBondContact O-CB 3.46Å; Y533-F537 PolarHBondContact O-N 3.02Å
534	L	89.1	Confident	86.6	Confident	0 Å²	0	58.8 Å²	58.8	0%	0	28%	0.284	C	S	.	.	H	α-helix	trans	-66.1	-41.6	178.7	-66.8	173.8	0	0	0	112.2	Y135 L143 F448 I451 F530 V531 F532 F537 G538	Y135-L534 HydrophobicContact CD1-CD2 4.39Å; Y135-L534 HydrophobicContact CE1-CD2 3.63Å; L143-L534 HydrophobicContact CD1-CD2 3.96Å; L143-L534 HydrophobicContact CD2-CD1 3.68Å; L143-L534 HydrophobicContact CD2-CD2 4.21Å; L143-L534 HydrophobicContact CG-CD2 4.22Å; F448-L534 HydrophobicContact CD1-CD1 3.72Å; F448-L534 HydrophobicContact CE1-CD1 4.28Å; I451-L534 HydrophobicContact CD1-CB 4.44Å; I451-L534 HydrophobicContact CG2-CB 3.83Å; F530-L534 HydrophobicContact CD1-CD1 4.24Å; F530-L534 HydrophobicContact CE1-CD1 3.89Å; F530-L534 HydrophobicContact CE1-CG 4.36Å; F530-L534 HydrophobicContact CE2-CD2 4.34Å; F530-L534 HydrophobicContact CE2-CG 4.43Å; F530-L534 HydrophobicContact CZ-CD1 4.2Å; F530-L534 HydrophobicContact CZ-CD2 4.09Å; F530-L534 HydrophobicContact CZ-CG 4.24Å; F530-L534 WeakPolarHBondContact O-CG 3.25Å; F530-L534 PolarHBondContact O-N 2.83Å; V531-L534 PolarHBondContact O-N 3.41Å; F532-L534 VanDerWaalsContact C-N 3.34Å; F532-L534 PolarHBondContact O-N 3.49Å; L534-F537 PolarHBondContact O-N 2.97Å; L534-G538 PolarHBondContact O-N 3.07Å
535	I	85.3	Confident	86.4	Confident	56 Å²	56	56.9 Å²	56.9	29%	0.287	28%	0.276	S	S	.	.	H	α-helix	trans	-62.6	-47.8	175.6	-66.1	169.4	0	0	0	110.2	I451 V531 F532 G538 F539	I451-I535 HydrophobicContact CD1-CD1 4.3Å; I451-I535 HydrophobicContact CD1-CG1 3.8Å; I451-I535 HydrophobicContact CG1-CG1 4.3Å; I451-I535 HydrophobicContact CG2-CG1 4.42Å; V531-I535 HydrophobicContact CG1-CD1 3.99Å; V531-I535 WeakPolarHBondContact O-CG1 3.43Å; V531-I535 PolarHBondContact O-N 2.82Å; F532-I535 PolarHBondContact O-N 2.71Å; I535-G538 PolarHBondContact O-N 3.37Å; I535-F539 PolarHBondContact O-N 3.44Å
536	W	87.8	Confident	85.5	Confident	143 Å²	143	56.8 Å²	56.8	54%	0.542	26%	0.263	S	S	.	.	H	α-helix	trans	-59.7	-47.2	177.4	173.2	-105.2	0	0	0	112	F532 Y533 G538 F539 I540	F532-W536 VanDerWaalsContact O-CB 3.26Å; F532-W536 WeakPolarHBondContact O-CB 3.23Å; F532-W536 PolarHBondContact O-N 3.03Å; Y533-W536 PolarHBondContact O-N 2.84Å; W536-G538 PolarHBondContact O-N 3.22Å; W536-F539 WeakPolarHBondContact O-CB 3.12Å; W536-F539 PolarHBondContact O-N 3.32Å; W536-I540 HydrophobicContact CD2-CD1 4.08Å; W536-I540 HydrophobicContact CG-CD1 4.39Å; W536-I540 HydrophobicContact CZ2-CD1 3.64Å; W536-I540 HydrophobicContact CZ2-CG1 4.41Å; W536-I540 VanDerWaalsContact NE1-CD1 3.25Å; W536-I540 PolarHBondContact O-N 3.21Å; W536-I540 VanDerWaalsContact O-N 3.09Å
537	F	89.9	Confident	84.5	Confident	38 Å²	38	60.9 Å²	60.9	17%	0.167	27%	0.266	C	S	.	.	H	α-helix	trans	-58.5	-48	175.4	179.6	-84.7	0	0	0	111	E134 Y135 Y533 L534 F539 I540 H541	E134-F537 VanDerWaalsContact O-CZ 3.29Å; E134-F537 WeakPolarHBondContact O-CZ 3.45Å; Y135-F537 AromaticContact CD1-CD1 3.68Å; Y135-F537 HydrophobicContact CD1-CD1 3.68Å; Y135-F537 HydrophobicContact CD1-CD2 4.23Å; Y135-F537 AromaticContact CD1-CE1 3.62Å; Y135-F537 HydrophobicContact CD1-CE1 3.62Å; Y135-F537 HydrophobicContact CD1-CE2 4.19Å; Y135-F537 AromaticContact CD1-CG 4Å; Y135-F537 HydrophobicContact CD1-CG 4Å; Y135-F537 AromaticContact CD1-CZ 3.9Å; Y135-F537 HydrophobicContact CD1-CZ 3.9Å; Y135-F537 HydrophobicContact CE1-CB 4.19Å; Y135-F537 AromaticContact CE1-CD1 3.11Å; Y135-F537 HydrophobicContact CE1-CD1 3.11Å; Y135-F537 HydrophobicContact CE1-CD2 4.3Å; Y135-F537 AromaticContact CE1-CE1 3.45Å; Y135-F537 HydrophobicContact CE1-CE1 3.45Å; Y135-F537 VanDerWaalsContact CE1-CE1 3.45Å; Y135-F537 AromaticContact CE1-CG 3.61Å; Y135-F537 HydrophobicContact CE1-CG 3.61Å; Y135-F537 HydrophobicContact CE1-CZ 4.19Å; Y135-F537 HydrophobicContact CG-CE1 4.33Å; Y135-F537 AromaticContact CZ-CD1 3.8Å; Y533-F537 VanDerWaalsContact O-CB 3.27Å; Y533-F537 WeakPolarHBondContact O-CB 3.46Å; Y533-F537 PolarHBondContact O-N 3.02Å; L534-F537 PolarHBondContact O-N 2.97Å; F537-F539 VanDerWaalsContact C-N 3.31Å; F537-F539 PolarHBondContact O-N 3.47Å; F537-I540 PolarHBondContact O-N 2.94Å; F537-H541 HydrophobicContact CD1-CB 4.48Å; F537-H541 HydrophobicContact CE1-CB 4.19Å; F537-H541 WeakPolarHBondContact O-CB 3.46Å; F537-H541 PolarHBondContact O-N 3.38Å
538	G	84.3	Confident	83.3	Confident	0 Å²	0	62.7 Å²	62.7	0%	0	28%	0.28	C	S	.	.	H	α-helix	trans	-61.5	-39.1	179.8	0	0	0	0	0	112.8	T455 L534 I535 W536 H541 V542	T455-G538 VanDerWaalsContact CG2-CA 3.43Å; T455-G538 WeakPolarHBondContact OG1-CA 3.2Å; L534-G538 PolarHBondContact O-N 3.07Å; I535-G538 PolarHBondContact O-N 3.37Å; W536-G538 PolarHBondContact O-N 3.22Å; G538-H541 PolarHBondContact O-N 2.91Å; G538-V542 WeakPolarHBondContact O-CB 3.35Å; G538-V542 VanDerWaalsContact O-CG2 3.27Å; G538-V542 WeakPolarHBondContact O-CG2 3.44Å; G538-V542 PolarHBondContact O-N 2.93Å; G538-V542 VanDerWaalsContact O-N 3.08Å
539	F	82.6	Confident	81.8	Confident	61 Å²	61	63.5 Å²	63.5	27%	0.268	29%	0.289	S	S	.	.	H	α-helix	trans	-59.5	-49.9	173.9	-175.2	-90.2	0	0	0	112	F478 I535 W536 F537 W543	F478-F539 AromaticContact CD2-CD2 3.54Å; F478-F539 HydrophobicContact CD2-CD2 3.54Å; F478-F539 HydrophobicContact CD2-CE2 4.13Å; F478-F539 HydrophobicContact CE2-CB 3.87Å; F478-F539 AromaticContact CE2-CD2 3.38Å; F478-F539 HydrophobicContact CE2-CD2 3.38Å; F478-F539 HydrophobicContact CE2-CE2 4.31Å; F478-F539 HydrophobicContact CE2-CG 4.08Å; F478-F539 HydrophobicContact CZ-CB 4.16Å; F478-F539 HydrophobicContact CZ-CD2 4.4Å; I535-F539 PolarHBondContact O-N 3.44Å; W536-F539 WeakPolarHBondContact O-CB 3.12Å; W536-F539 PolarHBondContact O-N 3.32Å; F537-F539 VanDerWaalsContact C-N 3.31Å; F537-F539 PolarHBondContact O-N 3.47Å; F539-W543 VanDerWaalsContact O-CB 3.24Å; F539-W543 WeakPolarHBondContact O-CB 3.4Å; F539-W543 PolarHBondContact O-N 3.48Å
540	I	85.6	Confident	80.1	Confident	58 Å²	58	66 Å²	66	30%	0.297	29%	0.292	S	S	.	.	H	α-helix	trans	-63.7	-43.6	179	-68.4	171.4	0	0	0	111.2	W536 F537 W543 R544	W536-I540 HydrophobicContact CD2-CD1 4.08Å; W536-I540 HydrophobicContact CG-CD1 4.39Å; W536-I540 HydrophobicContact CZ2-CD1 3.64Å; W536-I540 HydrophobicContact CZ2-CG1 4.41Å; W536-I540 VanDerWaalsContact NE1-CD1 3.25Å; W536-I540 PolarHBondContact O-N 3.21Å; W536-I540 VanDerWaalsContact O-N 3.09Å; F537-I540 PolarHBondContact O-N 2.94Å; I540-W543 PolarHBondContact O-N 3.47Å; I540-R544 WeakPolarHBondContact O-CB 2.87Å; I540-R544 PolarHBondContact O-N 2.88Å
541	H	85.2	Confident	77.7	Confident	27 Å²	27	68.9 Å²	68.9	13%	0.125	32%	0.32	C	S	.	.	H	α-helix	trans	-60.6	-52.4	-177.1	-172.7	-83.2	0	0	0	111.7	E134 T455 S459 F537 G538 W543 R544 S545	E134-H541 VanDerWaalsContact CD-NE2 3.29Å; E134-H541 IonicContact OE1-NE2 2.9Å; E134-H541 IonicContact OE2-CD2 3.92Å; E134-H541 PolarHBondContact OE2-CD2 3.17Å; E134-H541 IonicContact OE2-CE1 2.7Å; E134-H541 IonicContact OE2-NE2 3.12Å; E134-H541 PolarHBondContact OE2-NE2 3.13Å; T455-H541 HydrophobicContact CG2-CB 4.3Å; S459-H541 PolarHBondContact OG-CE1 3.15Å; S459-H541 VanDerWaalsContact OG-CE1 3.26Å; S459-H541 PolarHBondContact OG-ND1 3.38Å; F537-H541 HydrophobicContact CD1-CB 4.48Å; F537-H541 HydrophobicContact CE1-CB 4.19Å; F537-H541 WeakPolarHBondContact O-CB 3.46Å; F537-H541 PolarHBondContact O-N 3.38Å; G538-H541 PolarHBondContact O-N 2.91Å; H541-W543 VanDerWaalsContact C-N 3.29Å; H541-W543 PolarHBondContact O-N 2.87Å; H541-R544 PolarHBondContact O-N 2.84Å; H541-S545 WeakPolarHBondContact O-CB 3.37Å; H541-S545 PolarHBondContact O-N 3.08Å
542	V	80.1	Confident	75.4	Confident	3 Å²	3	73.8 Å²	73.8	2%	0.018	35%	0.35	C	S	.	.	H	α-helix	trans	-60.1	-43	177	169	0	0	0	0	110.6	T455 M477 G538 S545 R546	T455-V542 HydrophobicContact CG2-CG2 4.41Å; M477-V542 HydrophobicContact CE-CB 4.2Å; M477-V542 HydrophobicContact CE-CG1 3.45Å; M477-V542 VanDerWaalsContact CE-CG1 3.45Å; M477-V542 HydrophobicContact CE-CG2 3.91Å; M477-V542 HydrophobicContact SD-CG1 3.41Å; M477-V542 WeakPolarHBondContact SD-CG1 3.39Å; G538-V542 WeakPolarHBondContact O-CB 3.35Å; G538-V542 VanDerWaalsContact O-CG2 3.27Å; G538-V542 WeakPolarHBondContact O-CG2 3.44Å; G538-V542 PolarHBondContact O-N 2.93Å; G538-V542 VanDerWaalsContact O-N 3.08Å; V542-S545 PolarHBondContact O-N 3.33Å; V542-R546 WeakPolarHBondContact O-CG 3.09Å; V542-R546 PolarHBondContact O-N 3.17Å
543	W	78.5	Confident	72.7	Confident	99 Å²	99	72.8 Å²	72.8	38%	0.375	36%	0.355	S	S	.	.	H	α-helix	trans	-60.6	-45.9	178.6	-178.9	87	0	0	0	111.9	F539 I540 H541 R546 R547	F539-W543 VanDerWaalsContact O-CB 3.24Å; F539-W543 WeakPolarHBondContact O-CB 3.4Å; F539-W543 PolarHBondContact O-N 3.48Å; I540-W543 PolarHBondContact O-N 3.47Å; H541-W543 VanDerWaalsContact C-N 3.29Å; H541-W543 PolarHBondContact O-N 2.87Å; W543-R546 PolarHBondContact O-N 2.93Å; W543-R547 VanDerWaalsContact CH2-CZ 3.42Å; W543-R547 VanDerWaalsContact CH2-NH1 3.33Å
544	R	83.9	Confident	69.8	Low	169 Å²	169	74.5 Å²	74.5	64%	0.638	37%	0.374	S	S	*	.	H	α-helix	trans	-65.5	-42.7	177.1	-175.2	178.3	-80.1	168.9	-5.4	111.5	I540 H541 R546 R547 T548	I540-R544 WeakPolarHBondContact O-CB 2.87Å; I540-R544 PolarHBondContact O-N 2.88Å; H541-R544 PolarHBondContact O-N 2.84Å; R544-R546 PolarHBondContact O-N 3.38Å; R544-R547 PolarHBondContact O-N 3.45Å; R544-T548 PolarHBondContact O-N 3.11Å
545	S	78.9	Confident	67.1	Low	5 Å²	5	81.3 Å²	81.3	4%	0.035	41%	0.41	C	S	.	.	H	α-helix	trans	-61.6	-24.8	179.2	171.3	0	0	0	0	113.8	S459 R460 S461 H541 V542 T548	S459-S545 WeakPolarHBondContact OG-CB 3.16Å; S459-S545 PolarHBondContact OG-OG 3.47Å; R460-S545 WeakPolarHBondContact CA-OG 3.11Å; R460-S545 WeakPolarHBondContact CB-OG 2.97Å; R460-S545 PolarHBondContact N-OG 3.09Å; S461-S545 PolarHBondContact N-OG 3.34Å; H541-S545 WeakPolarHBondContact O-CB 3.37Å; H541-S545 PolarHBondContact O-N 3.08Å; V542-S545 PolarHBondContact O-N 3.33Å; S545-T548 PolarHBondContact O-OG1 3.07Å
546	R	70	Confident	64.6	Low	58 Å²	58	85.4 Å²	85.4	22%	0.219	43%	0.432	C	S	.	.	H	α-helix	trans	-75	-26.1	174.4	-72.3	-179.2	-178.5	-147	-1.1	113.1	T471 N472 M477 V542 W543 R544	T471-R546 PolarHBondContact O-NH1 2Å; T471-R546 PolarHBondContact O-NH2 3.32Å; N472-R546 PolarHBondContact O-NH1 3.02Å; M477-R546 PolarHBondContact SD-NH2 3.37Å; V542-R546 WeakPolarHBondContact O-CG 3.09Å; V542-R546 PolarHBondContact O-N 3.17Å; W543-R546 PolarHBondContact O-N 2.93Å; R544-R546 PolarHBondContact O-N 3.38Å
547	R	69.6	Low	62.4	Low	176 Å²	176	87.6 Å²	87.6	66%	0.664	45%	0.45	S	S	*	.	H	α-helix	trans	-86.8	-17.9	-178.1	-70.9	-173	174.1	-164.8	-4.5	113.7	W543 R544 P549	W543-R547 VanDerWaalsContact CH2-CZ 3.42Å; W543-R547 VanDerWaalsContact CH2-NH1 3.33Å; R544-R547 PolarHBondContact O-N 3.45Å; R547-P549 VanDerWaalsContact O-CD 3.31Å; R547-P549 WeakPolarHBondContact O-CD 3.35Å
548	T	63.5	Low	60	Low	66 Å²	66	92.2 Å²	92.2	41%	0.405	48%	0.477	S	S	.	.	S	Bend	trans	-74.3	116.4	176.5	48.7	0	0	0	0	109.7	R544 S545	R544-T548 PolarHBondContact O-N 3.11Å; S545-T548 PolarHBondContact O-OG1 3.07Å
549	P	54.6	Low	57.5	Low	79 Å²	79	104 Å²	104	51%	0.513	52%	0.522	S	S	.	.			trans	-62.4	141.3	171	26.2	-31.5	0	0	0	109.3	R547 A551	R547-P549 VanDerWaalsContact O-CD 3.31Å; R547-P549 WeakPolarHBondContact O-CD 3.35Å; P549-A551 PolarHBondContact O-N 3.08Å
550	I	55.6	Low	55.4	Low	95 Å²	95	105.9 Å²	105.9	49%	0.487	54%	0.542	S	S	.	.			trans	-76.8	114.1	168.9	-61.3	172.4	0	0	0	105.1	V552	I550-V552 VanDerWaalsContact C-N 3.33Å; I550-V552 HydrophobicContact CG2-CG2 4.27Å; I550-V552 PolarHBondContact O-N 3.33Å
551	A	41.8	Very low	52.6	Low	85 Å²	85	111.1 Å²	111.1	70%	0.702	57%	0.57	S	S	*	*			trans	-65.3	97.8	168.7	0	0	0	0	0	107.9	P549 V553	P549-A551 PolarHBondContact O-N 3.08Å; A551-V553 PolarHBondContact O-N 3.37Å
552	V	37.7	Very low	50.1	Low	111 Å²	111	114.1 Å²	114.1	67%	0.673	59%	0.594	S	S	*	*			trans	-80.2	101.2	168.2	-178	0	0	0	0	106	I550 T554	I550-V552 VanDerWaalsContact C-N 3.33Å; I550-V552 HydrophobicContact CG2-CG2 4.27Å; I550-V552 PolarHBondContact O-N 3.33Å; V552-T554 HydrophobicContact CG1-CG2 4.28Å; V552-T554 PolarHBondContact O-N 3.25Å; V552-T554 VanDerWaalsContact O-N 3.12Å
553	V	31.5	Very low	47.8	Very low	120 Å²	120	120 Å²	120	73%	0.727	63%	0.63	S	S	*	*			trans	-78.2	94.5	170.4	-178.1	0	0	0	0	107.1	A551 L555	A551-V553 PolarHBondContact O-N 3.37Å; V553-L555 PolarHBondContact O-N 3.12Å
554	T	30.7	Very low	45.7	Very low	116 Å²	116	121.3 Å²	121.3	71%	0.712	64%	0.643	S	S	*	*			trans	-72.9	107.6	162.5	36.1	0	0	0	0	108	V552 N556	V552-T554 HydrophobicContact CG1-CG2 4.28Å; V552-T554 PolarHBondContact O-N 3.25Å; V552-T554 VanDerWaalsContact O-N 3.12Å; T554-N556 VanDerWaalsContact C-N 3.34Å; T554-N556 PolarHBondContact O-N 3.49Å
555	L	31.4	Very low	43.2	Very low	143 Å²	143	119.7 Å²	119.7	75%	0.749	65%	0.646	S	S	*	*			trans	-70	95.5	166.2	-83.6	164.9	0	0	0	107.9	V553	V553-L555 PolarHBondContact O-N 3.12Å
556	N	33	Very low	41	Very low	142 Å²	142	125.5 Å²	125.5	76%	0.759	68%	0.682	S	S	*	*			trans	-75.5	125.8	164.4	-139.8	-6	0	0	0	107.4	T554 D558	T554-N556 VanDerWaalsContact C-N 3.34Å; T554-N556 PolarHBondContact O-N 3.49Å; N556-D558 PolarHBondContact O-N 3.47Å
557	M	41.4	Very low	39	Very low	188 Å²	188	125.7 Å²	125.7	93%	0.926	70%	0.702	S	S	*	*	S	Bend	trans	-68.1	-0.3	-173.4	-79.7	-177.2	65.8	0	0	114.2
558	D	40.1	Very low	37.1	Very low	136 Å²	136	121.8 Å²	121.8	73%	0.727	71%	0.707	S	S	*	*	S	Bend	trans	-111.3	117.2	174.5	-83.3	-40.9	0	0	0	112.1	N556 S560	N556-D558 PolarHBondContact O-N 3.47Å; D558-S560 PolarHBondContact O-N 3.11Å; D558-S560 VanDerWaalsContact O-N 3.1Å
559	R	31	Very low	35.6	Very low	248 Å²	248	125.1 Å²	125.1	94%	0.936	73%	0.727	S	S	*	*	S	Bend	trans	1.3	90	161.4	-72.2	175.5	171.3	176.1	-2.1	116.2
560	S	38.6	Very low	34.3	Very low	99 Å²	99	129.4 Å²	129.4	69%	0.692	75%	0.746	S	S	*	*			trans	166.9	124.9	138	45.3	0	0	0	0	109.4	D558 S562	D558-S560 PolarHBondContact O-N 3.11Å; D558-S560 VanDerWaalsContact O-N 3.1Å; S560-S562 PolarHBondContact O-N 3.38Å; S560-S562 VanDerWaalsContact O-N 3.11Å
561	L	28.2	Very low	33.1	Very low	168 Å²	168	130.5 Å²	130.5	88%	0.88	76%	0.757	S	S	*	*			trans	-68	108.7	169	-113.4	94.5	0	0	0	107.7
562	S	31.1	Very low	32.4	Very low	90 Å²	90	132.9 Å²	132.9	63%	0.629	76%	0.763	S	S	*	*			trans	-115.8	122.5	163.6	53.8	0	0	0	0	108.7	S560	S560-S562 PolarHBondContact O-N 3.38Å; S560-S562 VanDerWaalsContact O-N 3.11Å
563	V	33	Very low	32.3	Very low	128 Å²	128	135 Å²	135	78%	0.776	77%	0.769	S	S	*	*			trans	-85.4	108.1	171	178.6	0	0	0	0	106.1
564	I	34.3	Very low	32.3	Very low	126 Å²	126	137.3 Å²	137.3	65%	0.646	78%	0.777	S	S	*	*			trans	-95	110.1	173.7	-57.4	179.1	0	0	0	108	V566	I564-V566 HydrophobicContact CG2-CG2 3.7Å; I564-V566 PolarHBondContact O-N 3.5Å
565	D	30.7	Very low	32.5	Very low	134 Å²	134	135.3 Å²	135.3	72%	0.717	78%	0.78	S	S	*	*			trans	-78.6	101.5	169.5	-123	-20.2	0	0	0	108.4	G567	D565-G567 PolarHBondContact O-N 3.33Å
566	V	32.3	Very low	32.8	Very low	128 Å²	128	136.5 Å²	136.5	78%	0.776	79%	0.787	S	S	*	*			trans	-92.8	85.2	174.8	-171.8	0	0	0	0	109	I564	I564-V566 HydrophobicContact CG2-CG2 3.7Å; I564-V566 PolarHBondContact O-N 3.5Å
567	G	28.9	Very low	32.9	Very low	62 Å²	62	133.1 Å²	133.1	64%	0.639	79%	0.785	S	S	*	*			trans	-125.8	105.5	172.6	0	0	0	0	0	111.8	D565	D565-G567 PolarHBondContact O-N 3.33Å
568	A	28.7	Very low	32.5	Very low	93 Å²	93	128 Å²	128	77%	0.769	78%	0.781	S	S	*	*			trans	48.3	95.7	156.2	0	0	0	0	0	119.1
569	T	33	Very low	32.2	Very low	136 Å²	136	129.3 Å²	129.3	83%	0.834	79%	0.788	S	S	*	*			trans	-178.9	139.7	134.6	26	0	0	0	0	111.7	V571	T569-V571 PolarHBondContact O-N 3.01Å
570	N	27	Very low	32.3	Very low	169 Å²	169	128.8 Å²	128.8	90%	0.904	79%	0.786	S	S	*	*			trans	-53.5	124.1	168.2	-70.8	-24.9	0	0	0	110.8
571	V	30.9	Very low	32	Very low	118 Å²	118	128.4 Å²	128.4	72%	0.715	78%	0.783	S	S	*	*			trans	-130.5	108.6	164	-178.5	0	0	0	0	108.9	T569	T569-V571 PolarHBondContact O-N 3.01Å
572	T	27.8	Very low	32.1	Very low	136 Å²	136	126.9 Å²	126.9	83%	0.834	78%	0.781	S	S	*	*			trans	-67.8	125.2	164.7	38.8	0	0	0	0	109.8
573	I	34.2	Very low	32.1	Very low	155 Å²	155	127.7 Å²	127.7	80%	0.795	79%	0.787	S	S	*	*			trans	-97.8	105.1	172.4	-58.6	178.5	0	0	0	108
574	N	32.8	Very low	32.1	Very low	169 Å²	169	130.4 Å²	130.4	90%	0.904	79%	0.791	S	S	*	*			trans	-95.5	112.1	157.4	-91.1	-8.3	0	0	0	107.1
575	G	34.5	Very low	31.8	Very low	74 Å²	74	132.9 Å²	132.9	76%	0.763	80%	0.8	S	S	*	*			trans	-108.9	113.6	170.8	0	0	0	0	0	109.6
576	D	37.5	Very low	31.9	Very low	168 Å²	168	133.4 Å²	133.4	90%	0.898	81%	0.808	S	S	*	*			trans	-95.1	136.9	173.8	-166.8	11.7	0	0	0	110.9
577	G	34.6	Very low	31.7	Very low	71 Å²	71	134.1 Å²	134.1	73%	0.732	81%	0.807	S	S	*	*			trans	29.9	123.3	155.4	0	0	0	0	0	122.7
578	G	34	Very low	31.8	Very low	81 Å²	81	139 Å²	139	84%	0.835	81%	0.813	S	S	*	*			trans	170.3	78.5	155.5	0	0	0	0	0	117.3
579	N	32.7	Very low	31.9	Very low	162 Å²	162	143 Å²	143	87%	0.866	81%	0.813	S	S	*	*			trans	-34.8	134.7	173.1	-82.1	-29.4	0	0	0	118.1
580	R	33.3	Very low	31.6	Very low	237 Å²	237	143 Å²	143	89%	0.894	81%	0.813	S	S	*	*				-177.1	109.7	113.4	-103.5	174.3	178.6	169.8	0.2	114.3
581	S	33.1	Very low	31.6	Very low	92 Å²	92	142.1 Å²	142.1	64%	0.643	81%	0.805	S	S	*	*			trans	43.6	120	134.4	60.8	0	0	0	0	122.8
582	T	30.2	Very low	31.4	Very low	135 Å²	135	142.5 Å²	142.5	83%	0.828	81%	0.807	S	S	*	*			trans	63.7	124.5	134.9	58.6	0	0	0	0	117.4
583	S	30.9	Very low	31.6	Very low	108 Å²	108	142.8 Å²	142.8	76%	0.755	80%	0.803	S	S	*	*			cis	-169.2	163.5	37	49.8	0	0	0	0	111.2
584	E	33.1	Very low	31.5	Very low	184 Å²	184	144.1 Å²	144.1	86%	0.86	83%	0.826	S	S	*	*			trans	90.5	107.4	163.6	-65.2	-170.6	145.4	0	0	119.4
585	E	28	Very low	31.4	Very low	178 Å²	178	142.9 Å²	142.9	83%	0.832	82%	0.822	S	S	*	*			trans	-60.6	132.1	165.2	-71	168.6	115.1	0	0	111.4
586	T	32.5	Very low	31.2	Very low	146 Å²	146	146.5 Å²	146.5	90%	0.896	83%	0.826	S	S	*	*			trans	-142.7	102.5	143.9	-20.9	0	0	0	0	109
587	L	27.6	Very low	30.9	Very low	142 Å²	142	145.3 Å²	145.3	74%	0.743	82%	0.821	S	S	*	*			trans	-84.8	107.2	-176.2	-171.4	132	0	0	0	108.8
588	H	31.3	Very low	30.7	Very low	166 Å²	166	149.7 Å²	149.7	77%	0.769	83%	0.827	S	S	*	*			trans	-149.8	92.3	162.7	-107.6	-76.7	0	0	0	114.4
589	K	30.4	Very low	30.5	Very low	176 Å²	176	154 Å²	154	77%	0.765	83%	0.826	S	S	*	*			trans	45	89.1	137.2	-67.4	179	177.2	174.9	0	118.5	M591	K589-M591 PolarHBondContact O-N 3.35Å
590	T	26.3	Very low	30.3	Very low	137 Å²	137	153.5 Å²	153.5	84%	0.84	82%	0.824	S	S	*	*			trans	-72.6	101.5	150.1	-40.6	0	0	0	0	109	V592	T590-V592 PolarHBondContact O-N 3.43Å
591	M	28.3	Very low	30.1	Very low	149 Å²	149	147.5 Å²	147.5	73%	0.734	82%	0.818	S	S	*	*			trans	-86.5	97.5	169.1	-163	174.8	-175.3	0	0	108.5	K589 L593	K589-M591 PolarHBondContact O-N 3.35Å; M591-L593 HydrophobicContact CE-CD1 3.76Å; M591-L593 HydrophobicContact CE-CD2 4.13Å; M591-L593 HydrophobicContact CE-CG 3.95Å; M591-L593 HydrophobicContact CG-CD1 4.23Å; M591-L593 HydrophobicContact CG-CG 4.17Å; M591-L593 PolarHBondContact O-N 2.65Å; M591-L593 HydrophobicContact SD-CD1 3.91Å; M591-L593 HydrophobicContact SD-CG 4.38Å
592	V	26.8	Very low	29.9	Very low	127 Å²	127	151.8 Å²	151.8	77%	0.77	83%	0.832	S	S	*	*			trans	-68.4	111.5	161.7	177.7	0	0	0	0	106.6	T590	T590-V592 PolarHBondContact O-N 3.43Å
593	L	31.4	Very low	29.8	Very low	142 Å²	142	153.2 Å²	153.2	74%	0.743	83%	0.832	S	S	*	*			trans	-109.3	118.8	165.7	-88.8	161	0	0	0	107.9	M591	M591-L593 HydrophobicContact CE-CD1 3.76Å; M591-L593 HydrophobicContact CE-CD2 4.13Å; M591-L593 HydrophobicContact CE-CG 3.95Å; M591-L593 HydrophobicContact CG-CD1 4.23Å; M591-L593 HydrophobicContact CG-CG 4.17Å; M591-L593 PolarHBondContact O-N 2.65Å; M591-L593 HydrophobicContact SD-CD1 3.91Å; M591-L593 HydrophobicContact SD-CG 4.38Å
594	S	31.4	Very low	29.7	Very low	183 Å²	183	157.3 Å²	157.3	100%	1.28	84%	0.839	S	S	*	*			trans	-70.4	0	-175.4	-173.4	0	0	0	0	114.2

Retrieved 594 of 594 residues in 1050.5 ms (Link to these results)

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