A0A5K4ET74_SCHMA Loading...

Putative cationic amino acid transporter

AlphaFold DB , UniProt , Accession A0A5K4ET74, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 481 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	45.6	Very low	38.3	Very low	194 Å²	194	137.9 Å²	137.9	96%	0.956	68%	0.68	S	S	*	*				0	-29.7	0	-116.9	-165.8	-48.8	0	0	114.4
2	I	43.5	Very low	38.3	Very low	160 Å²	160	135.7 Å²	135.7	82%	0.821	67%	0.673	S	S	*	*			trans	-87.3	-24.3	173.9	-64.7	171.3	0	0	0	111.9
3	E	35.3	Very low	38	Very low	174 Å²	174	136.2 Å²	136.2	81%	0.813	68%	0.68	S	S	*	*	H	α-helix	trans	-79.3	-31	176	-79.7	173.8	148	0	0	114.3	V5 H6	E3-V5 PolarHBondContact O-N 3.12Å; E3-H6 PolarHBondContact O-N 3.4Å
4	E	39.1	Very low	37.7	Very low	131 Å²	131	131.1 Å²	131.1	61%	0.612	68%	0.679	S	S	*	*	H	α-helix	trans	-68.6	-20.7	176.7	-80.3	173	139.3	0	0	113.4
5	V	42.3	Very low	37.5	Very low	97 Å²	97	134.9 Å²	134.9	59%	0.588	68%	0.681	S	S	*	*	H	α-helix	trans	-78.3	-25.5	178	-179.8	0	0	0	0	111.3	E3	E3-V5 PolarHBondContact O-N 3.12Å
6	H	36.1	Very low	37.3	Very low	133 Å²	133	135.5 Å²	135.5	62%	0.616	69%	0.687	S	S	*	*	H	α-helix	trans	-85.1	-16.4	177.8	-129.8	15.7	0	0	0	113.4	E3	E3-H6 PolarHBondContact O-N 3.4Å
7	E	33.5	Very low	37.4	Very low	129 Å²	129	136.7 Å²	136.7	60%	0.603	70%	0.696	S	S	*	*	H	α-helix	trans	-76.7	-31.2	171.4	-96.4	-171.5	152.5	0	0	113.1	D9 K10 I11	E7-D9 VanDerWaalsContact C-N 3.32Å; E7-D9 PolarHBondContact O-N 3.21Å; E7-K10 PolarHBondContact O-N 3.11Å; E7-I11 VanDerWaalsContact O-CG1 3.3Å; E7-I11 WeakPolarHBondContact O-CG1 3.44Å; E7-I11 PolarHBondContact O-N 2.96Å
8	L	37.6	Very low	37.6	Very low	118 Å²	118	136.1 Å²	136.1	62%	0.618	69%	0.692	S	S	*	*	H	α-helix	trans	-66.8	-31.7	176.6	-82.6	158.6	0	0	0	113.1
9	D	35.5	Very low	37.4	Very low	106 Å²	106	134.6 Å²	134.6	57%	0.567	69%	0.693	S	S	*	*	H	α-helix	trans	-76.2	-25.5	173.6	-79.9	-22.5	0	0	0	112.7	E7	E7-D9 VanDerWaalsContact C-N 3.32Å; E7-D9 PolarHBondContact O-N 3.21Å
10	K	34.1	Very low	37.7	Very low	155 Å²	155	133.6 Å²	133.6	67%	0.674	69%	0.693	S	S	*	*	H	α-helix	trans	-82.3	-29	176.4	-75.3	-174.5	179.4	179.3	0	113.3	E7 N12 N13	E7-K10 PolarHBondContact O-N 3.11Å; K10-N12 PolarHBondContact O-N 2.97Å; K10-N13 PolarHBondContact O-N 3.43Å
11	I	38.7	Very low	38	Very low	120 Å²	120	134.1 Å²	134.1	62%	0.615	70%	0.702	S	S	*	*	H	α-helix	trans	-70.1	-21.1	176.3	-67.4	165.9	0	0	0	111.8	E7	E7-I11 VanDerWaalsContact O-CG1 3.3Å; E7-I11 WeakPolarHBondContact O-CG1 3.44Å; E7-I11 PolarHBondContact O-N 2.96Å
12	N	38.2	Very low	38.1	Very low	111 Å²	111	132.4 Å²	132.4	59%	0.594	69%	0.691	S	S	*	*	G	3₁₀ helix	trans	-81.6	-11.4	175.8	-88.7	-16.3	0	0	0	115	K10 G14	K10-N12 PolarHBondContact O-N 2.97Å; N12-G14 PolarHBondContact O-N 3.08Å
13	N	34.2	Very low	38.7	Very low	142 Å²	142	129 Å²	129	76%	0.759	68%	0.675	S	S	*	*	G	3₁₀ helix	trans	-83.5	14.1	178.3	-76.9	-19	0	0	0	114.1	K10	K10-N13 PolarHBondContact O-N 3.43Å
14	G	34.1	Very low	40	Very low	65 Å²	65	128.8 Å²	128.8	67%	0.67	67%	0.671	S	S	*	*	G	3₁₀ helix	trans	-129.1	12.8	177.6	0	0	0	0	0	114.5	N12	N12-G14 PolarHBondContact O-N 3.08Å
15	R	35.1	Very low	41.7	Very low	188 Å²	188	128.7 Å²	128.7	71%	0.709	67%	0.668	S	S	*	*			trans	-121.9	75.2	170	-81.4	-178.3	175.7	166.1	-0.7	108.8	D17	R15-D17 PolarHBondContact O-N 3.08Å
16	D	34.3	Very low	43.4	Very low	145 Å²	145	128 Å²	128	78%	0.775	67%	0.665	S	S	*	*	T	Hydrogen-bonded Turn	trans	-55.3	133.7	161.5	-66.4	-42.2	0	0	0	108.5
17	D	37.7	Very low	45.5	Very low	156 Å²	156	122.4 Å²	122.4	83%	0.834	64%	0.639	S	S	*	*	T	Hydrogen-bonded Turn	trans	83	33.7	168	-52.2	-28.1	0	0	0	120.7	R15	R15-D17 PolarHBondContact O-N 3.08Å
18	I	41.9	Very low	48.1	Very low	125 Å²	125	117 Å²	117	64%	0.641	62%	0.619	S	S	*	*			trans	-106.2	106.2	151.4	-53.3	176.6	0	0	0	107.7	V20	I18-V20 PolarHBondContact O-N 2.92Å
19	P	34.3	Very low	50.6	Low	109 Å²	109	113.3 Å²	113.3	71%	0.708	60%	0.599	S	S	*	*			trans	-61.2	111.5	174.4	24.8	-30.4	0	0	0	107.4	V21	P19-V21 PolarHBondContact O-N 2.98Å
20	V	42.8	Very low	53.1	Low	113 Å²	113	111.7 Å²	111.7	69%	0.685	60%	0.6	S	S	*	*			trans	-58.8	109.9	172.6	-173.5	0	0	0	0	105.8	I18 Q22	I18-V20 PolarHBondContact O-N 2.92Å; V20-Q22 VanDerWaalsContact C-N 3.27Å; V20-Q22 HydrophobicContact CB-CG 4.44Å; V20-Q22 HydrophobicContact CG1-CG 4.06Å; V20-Q22 PolarHBondContact O-N 3.33Å
21	V	44.6	Very low	55.4	Low	146 Å²	146	107.1 Å²	107.1	89%	0.885	59%	0.588	S	S	*	*			trans	-67.5	91.2	-179	-179.7	0	0	0	0	107.4	P19	P19-V21 PolarHBondContact O-N 2.98Å
22	Q	46.6	Very low	57.6	Low	157 Å²	157	101.4 Å²	101.4	73%	0.734	56%	0.558	S	S	*	*	P	Polyproline II helix	trans	-94.2	139.8	175.7	-67.9	-174.4	-0.5	0	0	109.4	V20 K24	V20-Q22 VanDerWaalsContact C-N 3.27Å; V20-Q22 HydrophobicContact CB-CG 4.44Å; V20-Q22 HydrophobicContact CG1-CG 4.06Å; V20-Q22 PolarHBondContact O-N 3.33Å; Q22-K24 PolarHBondContact O-N 3.05Å
23	L	56.2	Low	60.1	Low	89 Å²	89	97.6 Å²	97.6	47%	0.466	54%	0.538	S	S	.	.	P	Polyproline II helix	trans	-58.2	130.6	174.4	-75.3	163.7	0	0	0	109.7	K25 E240 E241	L23-K25 PolarHBondContact O-N 2.77Å; L23-E240 HydrophobicContact CD1-CB 4.5Å; L23-E241 HydrophobicContact CB-CG 3.87Å; L23-E241 HydrophobicContact CD1-CG 4.16Å; L23-E241 HydrophobicContact CD2-CG 4.45Å; L23-E241 HydrophobicContact CG-CG 4.39Å
24	K	63.2	Low	62.4	Low	169 Å²	169	95.2 Å²	95.2	74%	0.735	53%	0.529	S	S	*	.	P	Polyproline II helix	trans	-68.5	123.2	-178.5	-170.8	177.5	178.6	177.1	0	109.4	Q22 T26	Q22-K24 PolarHBondContact O-N 3.05Å; K24-T26 HydrophobicContact CB-CG2 4.19Å; K24-T26 HydrophobicContact CD-CG2 4Å; K24-T26 HydrophobicContact CG-CG2 3.81Å; K24-T26 PolarHBondContact O-N 3.02Å; K24-T26 VanDerWaalsContact O-N 3.08Å
25	K	74.9	Confident	64.7	Low	129 Å²	129	94.4 Å²	94.4	56%	0.561	51%	0.508	S	S	*	.			trans	-65.2	108.4	171.5	-67.1	-177.9	178.8	-178.2	0	109.8	L23 E240 E241 N243	L23-K25 PolarHBondContact O-N 2.77Å; K25-E240 WeakPolarHBondContact CG-O 3.5Å; K25-E241 CarbonylContact C-O 3.23Å; K25-E241 VanDerWaalsContact CA-O 3.31Å; K25-E241 WeakPolarHBondContact CA-O 3.42Å; K25-N243 VanDerWaalsContact C-OD1 3.22Å; K25-N243 PolarHBondContact O-OD1 2.91Å
26	T	78.1	Confident	67.1	Low	84 Å²	84	85.5 Å²	85.5	52%	0.515	48%	0.475	S	S	.	.			trans	-131.7	-13.5	-176.8	56.1	0	0	0	0	112.8	K24 E241 N243	K24-T26 HydrophobicContact CB-CG2 4.19Å; K24-T26 HydrophobicContact CD-CG2 4Å; K24-T26 HydrophobicContact CG-CG2 3.81Å; K24-T26 PolarHBondContact O-N 3.02Å; K24-T26 VanDerWaalsContact O-N 3.08Å; T26-E241 PolarHBondContact N-O 3.47Å; T26-N243 PolarHBondContact N-OD1 2.9Å
27	I	79.7	Confident	69.6	Low	14 Å²	14	79.4 Å²	79.4	7%	0.072	44%	0.443	C	S	.	.	B	Isolated β-bridge	trans	-93.3	111.2	-172.5	-54.7	178.9	0	0	0	109.6	S32 I35 M238 E241 M242 N243	I27-S32 WeakPolarHBondContact CG2-OG 3.43Å; I27-I35 HydrophobicContact CD1-CD1 4.18Å; I27-I35 HydrophobicContact CG2-CD1 4.04Å; I27-M238 HydrophobicContact CD1-CB 4.15Å; I27-M238 HydrophobicContact CD1-SD 4.47Å; I27-E241 HydrophobicContact CD1-CB 3.66Å; I27-E241 HydrophobicContact CG1-CB 4.09Å; I27-E241 PolarHBondContact N-O 3Å; I27-M242 HydrophobicContact CB-CG 4.29Å; I27-M242 HydrophobicContact CG2-CG 4.26Å; I27-M242 WeakPolarHBondContact O-CA 3.47Å; I27-N243 PolarHBondContact O-N 3.24Å
28	G	88.2	Confident	71.7	Confident	17 Å²	17	72.7 Å²	72.7	18%	0.175	41%	0.411	C	S	.	.			trans	-91.5	-178	170.9	0	0	0	0	0	113.3	A30 S31 S32	G28-A30 PolarHBondContact O-N 2.89Å; G28-S31 PolarHBondContact O-N 2.84Å; G28-S32 WeakPolarHBondContact O-CB 3.32Å; G28-S32 PolarHBondContact O-N 3.27Å; G28-S32 PolarHBondContact O-OG 3.36Å
29	L	90.2	Very high	73.6	Confident	40 Å²	40	68.8 Å²	68.8	21%	0.209	39%	0.394	C	S	.	.	H	α-helix	trans	-56.7	-48.7	179.7	178	59.9	0	0	0	113.5	S31 S32 I33 D248 L251 A252	L29-S31 PolarHBondContact O-N 3.37Å; L29-S32 WeakPolarHBondContact O-CB 3.29Å; L29-S32 PolarHBondContact O-N 3.45Å; L29-S32 VanDerWaalsContact O-N 3.16Å; L29-I33 HydrophobicContact CD1-CD1 4.06Å; L29-I33 HydrophobicContact CD1-CG1 4.29Å; L29-I33 HydrophobicContact CG-CD1 4.08Å; L29-I33 WeakPolarHBondContact O-CG1 3.31Å; L29-I33 PolarHBondContact O-N 3.31Å; L29-D248 HydrophobicContact CB-CB 4.14Å; L29-D248 HydrophobicContact CD1-CB 4.15Å; L29-D248 WeakPolarHBondContact CD1-O 3.25Å; L29-L251 HydrophobicContact CD1-CB 3.88Å; L29-L251 HydrophobicContact CD2-CD1 4.38Å; L29-A252 HydrophobicContact CD1-CB 4.05Å
30	A	88.4	Confident	76.1	Confident	71 Å²	71	63.8 Å²	63.8	59%	0.587	36%	0.362	S	S	*	.	H	α-helix	trans	-61.9	-46.8	-178.7	0	0	0	0	0	111.4	G28 S32 I33 T34	G28-A30 PolarHBondContact O-N 2.89Å; A30-S32 VanDerWaalsContact C-N 3.28Å; A30-S32 PolarHBondContact O-N 3.46Å; A30-I33 PolarHBondContact O-N 2.76Å; A30-T34 PolarHBondContact O-N 2.76Å; A30-T34 PolarHBondContact O-OG1 2.98Å
31	S	82.6	Confident	78.2	Confident	59 Å²	59	58.6 Å²	58.6	41%	0.413	33%	0.33	S	S	.	.	H	α-helix	trans	-59.8	-39.7	174.6	-51.6	0	0	0	0	111.7	G28 L29 T34 I35	G28-S31 PolarHBondContact O-N 2.84Å; L29-S31 PolarHBondContact O-N 3.37Å; S31-T34 PolarHBondContact O-N 3.18Å; S31-I35 WeakPolarHBondContact O-CB 3.21Å; S31-I35 WeakPolarHBondContact O-CD1 3.46Å; S31-I35 WeakPolarHBondContact O-CG1 3.02Å; S31-I35 PolarHBondContact O-N 3Å
32	S	85.3	Confident	79.9	Confident	0 Å²	0	52.1 Å²	52.1	0%	0	29%	0.293	C	S	.	.	H	α-helix	trans	-62.1	-43.7	177.3	-58	0	0	0	0	112.4	I27 G28 L29 A30 I35 I36 M242	I27-S32 WeakPolarHBondContact CG2-OG 3.43Å; G28-S32 WeakPolarHBondContact O-CB 3.32Å; G28-S32 PolarHBondContact O-N 3.27Å; G28-S32 PolarHBondContact O-OG 3.36Å; L29-S32 WeakPolarHBondContact O-CB 3.29Å; L29-S32 PolarHBondContact O-N 3.45Å; L29-S32 VanDerWaalsContact O-N 3.16Å; A30-S32 VanDerWaalsContact C-N 3.28Å; A30-S32 PolarHBondContact O-N 3.46Å; S32-I35 PolarHBondContact O-N 3.21Å; S32-I36 PolarHBondContact O-N 2.8Å; S32-M242 WeakPolarHBondContact OG-CE 3.33Å
33	I	89.3	Confident	81.3	Confident	32 Å²	32	44.8 Å²	44.8	16%	0.164	26%	0.259	C	S	.	.	H	α-helix	trans	-62.2	-49.5	175.8	-66.8	164.5	0	0	0	109.8	L29 A30 I35 I36 V37 A252 I255 S256	L29-I33 HydrophobicContact CD1-CD1 4.06Å; L29-I33 HydrophobicContact CD1-CG1 4.29Å; L29-I33 HydrophobicContact CG-CD1 4.08Å; L29-I33 WeakPolarHBondContact O-CG1 3.31Å; L29-I33 PolarHBondContact O-N 3.31Å; A30-I33 PolarHBondContact O-N 2.76Å; I33-I35 VanDerWaalsContact C-N 3.28Å; I33-I35 PolarHBondContact O-N 3.48Å; I33-I36 PolarHBondContact O-N 2.83Å; I33-V37 HydrophobicContact CG2-CG2 3.97Å; I33-V37 WeakPolarHBondContact O-CB 3.35Å; I33-V37 VanDerWaalsContact O-CG2 3.26Å; I33-V37 WeakPolarHBondContact O-CG2 3.45Å; I33-V37 PolarHBondContact O-N 3.29Å; I33-A252 HydrophobicContact CG1-CB 4.03Å; I33-I255 HydrophobicContact CD1-CB 4.3Å; I33-I255 HydrophobicContact CD1-CD1 3.94Å; I33-I255 HydrophobicContact CD1-CG2 4.02Å; I33-I255 HydrophobicContact CG1-CG2 4.43Å; I33-I255 HydrophobicContact CG2-CG2 4.33Å; I33-S256 WeakPolarHBondContact CA-OG 3.45Å
34	T	83.7	Confident	82.7	Confident	92 Å²	92	40.8 Å²	40.8	56%	0.564	24%	0.239	S	C	*	.	H	α-helix	trans	-60.2	-38.3	178.8	-55.9	0	0	0	0	112	A30 S31 G38	A30-T34 PolarHBondContact O-N 2.76Å; A30-T34 PolarHBondContact O-OG1 2.98Å; S31-T34 PolarHBondContact O-N 3.18Å; T34-G38 WeakPolarHBondContact O-CA 3.32Å; T34-G38 PolarHBondContact O-N 3.02Å
35	I	81.6	Confident	84.1	Confident	47 Å²	47	32.7 Å²	32.7	24%	0.241	20%	0.204	C	C	.	.	H	α-helix	trans	-63.9	-48.3	176.1	-71.4	163.1	0	0	0	110.7	I27 S31 S32 I33 S39 L235	I27-I35 HydrophobicContact CD1-CD1 4.18Å; I27-I35 HydrophobicContact CG2-CD1 4.04Å; S31-I35 WeakPolarHBondContact O-CB 3.21Å; S31-I35 WeakPolarHBondContact O-CD1 3.46Å; S31-I35 WeakPolarHBondContact O-CG1 3.02Å; S31-I35 PolarHBondContact O-N 3Å; S32-I35 PolarHBondContact O-N 3.21Å; I33-I35 VanDerWaalsContact C-N 3.28Å; I33-I35 PolarHBondContact O-N 3.48Å; I35-S39 WeakPolarHBondContact O-CB 3.4Å; I35-S39 PolarHBondContact O-N 3.18Å; I35-S39 PolarHBondContact O-OG 3.42Å; I35-L235 HydrophobicContact CG2-CD1 4.26Å
36	I	86.2	Confident	84.7	Confident	1 Å²	1	26.7 Å²	26.7	1%	0.005	18%	0.177	C	C	.	.	H	α-helix	trans	-66.4	-52	180	-66.8	170.7	0	0	0	110.5	S32 I33 G38 S39 M40 W232 L235 A252 I253	S32-I36 PolarHBondContact O-N 2.8Å; I33-I36 PolarHBondContact O-N 2.83Å; I36-G38 VanDerWaalsContact C-N 3.3Å; I36-G38 PolarHBondContact O-N 3.26Å; I36-S39 PolarHBondContact O-N 3.42Å; I36-M40 HydrophobicContact CG2-CG 4.14Å; I36-M40 HydrophobicContact CG2-SD 3.54Å; I36-M40 VanDerWaalsContact CG2-SD 3.54Å; I36-M40 WeakPolarHBondContact O-CG 3.44Å; I36-M40 PolarHBondContact O-N 3.42Å; I36-W232 HydrophobicContact CG2-CB 4.36Å; I36-L235 HydrophobicContact CD1-CB 4.19Å; I36-L235 HydrophobicContact CD1-CD2 3.48Å; I36-L235 VanDerWaalsContact CD1-CD2 3.48Å; I36-L235 HydrophobicContact CD1-CG 4.45Å; I36-L235 HydrophobicContact CG1-CB 3.92Å; I36-L235 HydrophobicContact CG1-CD2 3.88Å; I36-L235 HydrophobicContact CG1-CG 4.45Å; I36-A252 HydrophobicContact CD1-CB 4.07Å; I36-I253 HydrophobicContact CD1-CG1 3.98Å
37	V	87.3	Confident	85.2	Confident	18 Å²	18	23 Å²	23	11%	0.109	16%	0.155	C	C	.	.	H	α-helix	trans	-58.8	-46	-179.5	174.6	0	0	0	0	110.1	I33 S39 M40 I41 L259 V260	I33-V37 HydrophobicContact CG2-CG2 3.97Å; I33-V37 WeakPolarHBondContact O-CB 3.35Å; I33-V37 VanDerWaalsContact O-CG2 3.26Å; I33-V37 WeakPolarHBondContact O-CG2 3.45Å; I33-V37 PolarHBondContact O-N 3.29Å; V37-S39 VanDerWaalsContact C-N 3.28Å; V37-S39 PolarHBondContact O-N 3.25Å; V37-M40 PolarHBondContact O-N 2.89Å; V37-I41 HydrophobicContact CG1-CD1 3.55Å; V37-I41 HydrophobicContact CG1-CG1 4.15Å; V37-I41 VanDerWaalsContact O-CB 3.22Å; V37-I41 WeakPolarHBondContact O-CB 3.3Å; V37-I41 VanDerWaalsContact O-CG1 3.32Å; V37-I41 WeakPolarHBondContact O-CG1 3.27Å; V37-I41 PolarHBondContact O-N 2.76Å; V37-L259 HydrophobicContact CG2-CD2 4.03Å; V37-V260 HydrophobicContact CB-CG2 4.48Å; V37-V260 HydrophobicContact CG1-CG2 4.28Å; V37-V260 HydrophobicContact CG2-CG2 4.31Å
38	G	81.4	Confident	85.8	Confident	15 Å²	15	22.4 Å²	22.4	16%	0.155	15%	0.152	C	C	.	.	H	α-helix	trans	-67.9	-23.1	176.6	0	0	0	0	0	113.8	T34 I36 K181	T34-G38 WeakPolarHBondContact O-CA 3.32Å; T34-G38 PolarHBondContact O-N 3.02Å; I36-G38 VanDerWaalsContact C-N 3.3Å; I36-G38 PolarHBondContact O-N 3.26Å; G38-K181 PolarHBondContact O-NZ 2.61Å
39	S	80.7	Confident	86.1	Confident	43 Å²	43	21.7 Å²	21.7	30%	0.301	14%	0.144	S	C	.	.	H	α-helix	trans	-84.3	-37.7	175.6	-61.1	0	0	0	0	112.1	I35 I36 V37	I35-S39 WeakPolarHBondContact O-CB 3.4Å; I35-S39 PolarHBondContact O-N 3.18Å; I35-S39 PolarHBondContact O-OG 3.42Å; I36-S39 PolarHBondContact O-N 3.42Å; V37-S39 VanDerWaalsContact C-N 3.28Å; V37-S39 PolarHBondContact O-N 3.25Å
40	M	87.4	Confident	86.2	Confident	4 Å²	4	20.2 Å²	20.2	2%	0.02	14%	0.137	C	C	.	.	H	α-helix	trans	-75.3	-49	178.3	-65.9	175.5	77.8	0	0	111.9	I36 V37 G42 A228 Y229 S230 W232 V260 Y264	I36-M40 HydrophobicContact CG2-CG 4.14Å; I36-M40 HydrophobicContact CG2-SD 3.54Å; I36-M40 VanDerWaalsContact CG2-SD 3.54Å; I36-M40 WeakPolarHBondContact O-CG 3.44Å; I36-M40 PolarHBondContact O-N 3.42Å; V37-M40 PolarHBondContact O-N 2.89Å; M40-G42 PolarHBondContact O-N 2.89Å; M40-A228 VanDerWaalsContact O-O 3.11Å; M40-Y229 HydrophobicContact CE-CD1 3.51Å; M40-Y229 HydrophobicContact CE-CE1 4.49Å; M40-Y229 HydrophobicContact CE-CG 4.24Å; M40-Y229 WeakPolarHBondContact CE-O 3.28Å; M40-S230 WeakPolarHBondContact CA-O 3.41Å; M40-W232 HydrophobicContact CE-CB 4.29Å; M40-W232 HydrophobicContact CG-CB 4.13Å; M40-W232 HydrophobicContact SD-CB 3.78Å; M40-V260 HydrophobicContact CB-CG1 4.27Å; M40-V260 HydrophobicContact CB-CG2 4.18Å; M40-V260 HydrophobicContact CE-CB 4.39Å; M40-V260 HydrophobicContact CE-CG1 4.15Å; M40-V260 HydrophobicContact SD-CG2 4.19Å; M40-Y264 PolarHBondContact O-OH 3.5Å
41	I	86.8	Confident	86.4	Confident	3 Å²	3	16.8 Å²	16.8	2%	0.015	11%	0.109	C	C	.	.	S	Bend	trans	-67.8	105.3	175.8	-61.7	-176.3	0	0	0	107.9	V37 K181 L185 V260 I263 Y264	V37-I41 HydrophobicContact CG1-CD1 3.55Å; V37-I41 HydrophobicContact CG1-CG1 4.15Å; V37-I41 VanDerWaalsContact O-CB 3.22Å; V37-I41 WeakPolarHBondContact O-CB 3.3Å; V37-I41 VanDerWaalsContact O-CG1 3.32Å; V37-I41 WeakPolarHBondContact O-CG1 3.27Å; V37-I41 PolarHBondContact O-N 2.76Å; I41-K181 HydrophobicContact CG2-CD 4.22Å; I41-K181 HydrophobicContact CG2-CG 4.27Å; I41-K181 WeakPolarHBondContact O-CD 3.41Å; I41-K181 WeakPolarHBondContact O-CE 3.44Å; I41-K181 PolarHBondContact O-NZ 3.17Å; I41-L185 HydrophobicContact CD1-CD1 4.36Å; I41-L185 HydrophobicContact CG2-CD1 3.37Å; I41-V260 HydrophobicContact CD1-CG2 4.29Å; I41-V260 HydrophobicContact CG1-CG1 4.37Å; I41-V260 HydrophobicContact CG1-CG2 3.98Å; I41-I263 HydrophobicContact CD1-CD1 3.86Å; I41-I263 HydrophobicContact CD1-CG2 4.37Å; I41-Y264 WeakPolarHBondContact CA-OH 3.47Å; I41-Y264 HydrophobicContact CG1-CE1 4.14Å
42	G	79.4	Confident	87	Confident	10 Å²	10	14 Å²	14	10%	0.103	9%	0.089	C	C	.	.	S	Bend	trans	-144	-140.4	-179.7	0	0	0	0	0	111.4	M40 S309	M40-G42 PolarHBondContact O-N 2.89Å; G42-S309 PolarHBondContact O-OG 2.86Å
43	S	76.3	Confident	87.3	Confident	4 Å²	4	14.4 Å²	14.4	3%	0.028	9%	0.091	C	C	.	.	S	Bend	trans	-74	-24.5	177.8	54.1	0	0	0	0	113.9	I45 F46 V47 M125 T310	S43-I45 VanDerWaalsContact C-N 3.3Å; S43-I45 PolarHBondContact O-N 3.42Å; S43-F46 WeakPolarHBondContact O-CB 3.2Å; S43-F46 PolarHBondContact O-N 2.83Å; S43-V47 PolarHBondContact O-N 3.26Å; S43-M125 VanDerWaalsContact OG-CG 3.23Å; S43-M125 WeakPolarHBondContact OG-CG 3.25Å; S43-T310 VanDerWaalsContact CB-CG2 3.46Å
44	G	87	Confident	87.5	Confident	4 Å²	4	18.4 Å²	18.4	4%	0.041	11%	0.109	C	C	.	.	H	α-helix	trans	-58.7	-39.1	-169.5	0	0	0	0	0	113.3	F46 V47 S48	G44-F46 PolarHBondContact O-N 2.81Å; G44-F46 VanDerWaalsContact O-N 3.08Å; G44-V47 PolarHBondContact O-N 3.43Å; G44-S48 WeakPolarHBondContact O-CB 3.31Å; G44-S48 PolarHBondContact O-N 3.28Å; G44-S48 PolarHBondContact O-OG 3.34Å
45	I	91.4	Very high	88	Confident	0 Å²	0	15 Å²	15	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-61.8	-19.3	176.6	-169.5	53.4	0	0	0	114.2	S43 P49 W66 L185 Y264 A267	S43-I45 VanDerWaalsContact C-N 3.3Å; S43-I45 PolarHBondContact O-N 3.42Å; I45-P49 WeakPolarHBondContact O-CD 3.32Å; I45-P49 WeakPolarHBondContact O-CG 3.48Å; I45-W66 HydrophobicContact CD1-CH2 3.6Å; I45-W66 HydrophobicContact CD1-CZ2 3.9Å; I45-W66 HydrophobicContact CD1-CZ3 4.11Å; I45-L185 HydrophobicContact CG1-CD2 3.95Å; I45-L185 HydrophobicContact CG2-CD1 4.36Å; I45-L185 HydrophobicContact CG2-CD2 3.94Å; I45-Y264 HydrophobicContact CB-CD1 3.94Å; I45-Y264 HydrophobicContact CB-CE1 3.64Å; I45-Y264 HydrophobicContact CD1-CD1 3.65Å; I45-Y264 HydrophobicContact CD1-CE1 4.26Å; I45-Y264 HydrophobicContact CD1-CG 3.86Å; I45-Y264 HydrophobicContact CG1-CD1 3.7Å; I45-Y264 HydrophobicContact CG1-CE1 3.94Å; I45-Y264 HydrophobicContact CG1-CG 4.41Å; I45-Y264 HydrophobicContact CG2-CE1 4.18Å; I45-A267 HydrophobicContact CD1-CB 4.4Å; I45-A267 HydrophobicContact CG1-CB 4.45Å
46	F	88.5	Confident	88.6	Confident	2 Å²	2	12.8 Å²	12.8	1%	0.009	8%	0.076	C	C	.	.	H	α-helix	trans	-93.4	-15.1	178.2	-58.8	-63.3	0	0	0	112.9	S43 G44 Y132 A184 L185 I188 A287 V306	S43-F46 WeakPolarHBondContact O-CB 3.2Å; S43-F46 PolarHBondContact O-N 2.83Å; G44-F46 PolarHBondContact O-N 2.81Å; G44-F46 VanDerWaalsContact O-N 3.08Å; F46-Y132 HydrophobicContact CB-CE2 4.29Å; F46-Y132 PolarHBondContact O-OH 3.43Å; F46-A184 HydrophobicContact CZ-CB 4.35Å; F46-L185 HydrophobicContact CE1-CD2 4.34Å; F46-L185 HydrophobicContact CZ-CD2 4.14Å; F46-L185 HydrophobicContact CZ-CG 4.36Å; F46-I188 HydrophobicContact CE1-CD1 4.07Å; F46-A287 HydrophobicContact CD1-CB 3.87Å; F46-A287 HydrophobicContact CE1-CB 4.22Å; F46-V306 HydrophobicContact CB-CG1 3.79Å; F46-V306 HydrophobicContact CD1-CG1 4.09Å; F46-V306 HydrophobicContact CD1-CG2 3.63Å; F46-V306 HydrophobicContact CD2-CB 4.44Å; F46-V306 HydrophobicContact CD2-CG1 3.65Å; F46-V306 HydrophobicContact CD2-CG2 4.23Å; F46-V306 HydrophobicContact CE1-CG2 3.57Å; F46-V306 HydrophobicContact CE2-CG1 4.24Å; F46-V306 HydrophobicContact CE2-CG2 4.18Å; F46-V306 HydrophobicContact CG-CB 4.4Å; F46-V306 HydrophobicContact CG-CG1 3.55Å; F46-V306 HydrophobicContact CG-CG2 3.97Å; F46-V306 HydrophobicContact CZ-CG2 3.86Å
47	V	88.2	Confident	88.9	Confident	8 Å²	8	16.4 Å²	16.4	5%	0.048	10%	0.095	C	C	.	.	H	α-helix	trans	-107.1	-41.6	-180	-178.9	0	0	0	0	111.9	S43 G44 P49 T128 I368 Y369 I372	S43-V47 PolarHBondContact O-N 3.26Å; G44-V47 PolarHBondContact O-N 3.43Å; V47-P49 VanDerWaalsContact C-CD 3.4Å; V47-T128 HydrophobicContact CG2-CG2 3.32Å; V47-T128 WeakPolarHBondContact CG2-OG1 3.49Å; V47-I368 HydrophobicContact CG1-CG2 4.01Å; V47-Y369 HydrophobicContact CG1-CE1 3.91Å; V47-Y369 PolarHBondContact O-OH 2.9Å; V47-I372 HydrophobicContact CG1-CD1 3.81Å
48	S	92.8	Very high	89.2	Confident	0 Å²	0	15.7 Å²	15.7	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-67.3	-29.2	-170.9	-61.6	0	0	0	0	115.7	G44 T50 G51 I52 V224	G44-S48 WeakPolarHBondContact O-CB 3.31Å; G44-S48 PolarHBondContact O-N 3.28Å; G44-S48 PolarHBondContact O-OG 3.34Å; S48-T50 PolarHBondContact O-N 3.29Å; S48-G51 PolarHBondContact O-N 3.3Å; S48-I52 WeakPolarHBondContact O-CB 3.3Å; S48-I52 VanDerWaalsContact O-CG1 3.3Å; S48-I52 WeakPolarHBondContact O-CG1 3.46Å; S48-I52 PolarHBondContact O-N 2.85Å; S48-V224 VanDerWaalsContact CA-CG1 3.48Å; S48-V224 WeakPolarHBondContact CB-O 3.45Å; S48-V224 PolarHBondContact OG-O 3.41Å
49	P	93.9	Very high	89.8	Confident	3 Å²	3	15.4 Å²	15.4	2%	0.019	9%	0.086	C	C	.	.	H	α-helix	trans	-54.9	-51.4	178.5	-28.6	36.1	0	0	0	113.1	I45 V47 I52 M53 W66 N268 Y271	I45-P49 WeakPolarHBondContact O-CD 3.32Å; I45-P49 WeakPolarHBondContact O-CG 3.48Å; V47-P49 VanDerWaalsContact C-CD 3.4Å; P49-I52 PolarHBondContact O-N 3.25Å; P49-M53 WeakPolarHBondContact O-CB 3.34Å; P49-M53 PolarHBondContact O-N 3.32Å; P49-W66 HydrophobicContact CG-CZ2 4.24Å; P49-N268 WeakPolarHBondContact CB-OD1 3.33Å; P49-Y271 HydrophobicContact CB-CD2 4.45Å; P49-Y271 HydrophobicContact CG-CD2 4.28Å; P49-Y271 HydrophobicContact CG-CE2 3.92Å
50	T	92.5	Very high	90.5	Very high	8 Å²	8	13.6 Å²	13.6	5%	0.049	7%	0.074	C	C	.	.	H	α-helix	trans	-62.3	-47.2	177.8	-58.5	0	0	0	0	111.1	S48 I52 M53 E54 I280 T283 V286 Y369	S48-T50 PolarHBondContact O-N 3.29Å; T50-I52 PolarHBondContact O-N 2.98Å; T50-M53 PolarHBondContact O-N 3.37Å; T50-E54 VanDerWaalsContact O-CB 3.32Å; T50-E54 WeakPolarHBondContact O-CB 3.08Å; T50-E54 PolarHBondContact O-N 3.19Å; T50-I280 VanDerWaalsContact CG2-O 3.31Å; T50-I280 WeakPolarHBondContact CG2-O 3.41Å; T50-I280 PolarHBondContact OG1-O 3.29Å; T50-T283 PolarHBondContact OG1-O 2.97Å; T50-V286 WeakPolarHBondContact OG1-CG2 3.49Å; T50-Y369 WeakPolarHBondContact CB-OH 3.38Å
51	G	91.9	Very high	90.9	Very high	0 Å²	0	13.4 Å²	13.4	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-68.3	-31.7	-177.7	0	0	0	0	0	114	S48 N55	S48-G51 PolarHBondContact O-N 3.3Å; G51-N55 PolarHBondContact O-N 2.77Å; G51-N55 PolarHBondContact O-ND2 3.23Å
52	I	94.9	Very high	91.3	Very high	0 Å²	0	13.6 Å²	13.6	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-69.1	-49.7	171.4	-67	164.8	0	0	0	109	S48 P49 T50 E54 N55 V56 S62 I65 W66 A221 V224	S48-I52 WeakPolarHBondContact O-CB 3.3Å; S48-I52 VanDerWaalsContact O-CG1 3.3Å; S48-I52 WeakPolarHBondContact O-CG1 3.46Å; S48-I52 PolarHBondContact O-N 2.85Å; P49-I52 PolarHBondContact O-N 3.25Å; T50-I52 PolarHBondContact O-N 2.98Å; I52-E54 VanDerWaalsContact C-N 3.28Å; I52-E54 PolarHBondContact O-N 2.99Å; I52-N55 PolarHBondContact O-N 3.21Å; I52-V56 HydrophobicContact CG2-CG2 4.11Å; I52-V56 WeakPolarHBondContact O-CG2 3.5Å; I52-V56 PolarHBondContact O-N 2.87Å; I52-S62 VanDerWaalsContact CG2-OG 3.23Å; I52-S62 WeakPolarHBondContact CG2-OG 3.45Å; I52-I65 HydrophobicContact CD1-CG2 4.36Å; I52-I65 HydrophobicContact CG1-CG2 4.41Å; I52-I65 HydrophobicContact CG2-CB 4.07Å; I52-I65 HydrophobicContact CG2-CG1 4.46Å; I52-I65 HydrophobicContact CG2-CG2 4.08Å; I52-W66 HydrophobicContact CD1-CD2 3.99Å; I52-W66 HydrophobicContact CD1-CG 4.31Å; I52-W66 HydrophobicContact CD1-CH2 4.45Å; I52-W66 HydrophobicContact CD1-CZ2 3.68Å; I52-A221 HydrophobicContact CG2-CB 4.33Å; I52-V224 HydrophobicContact CG1-CB 4.22Å; I52-V224 HydrophobicContact CG1-CG1 4.02Å
53	M	93.2	Very high	92.2	Very high	9 Å²	9	14.6 Å²	14.6	4%	0.044	8%	0.078	C	C	.	.	H	α-helix	trans	-59.3	-38.9	-177.4	-167.2	61.9	-138	0	0	112.2	P49 T50 N55 N57 S58 I59 I280 L281	P49-M53 WeakPolarHBondContact O-CB 3.34Å; P49-M53 PolarHBondContact O-N 3.32Å; T50-M53 PolarHBondContact O-N 3.37Å; M53-N55 VanDerWaalsContact C-N 3.29Å; M53-N55 PolarHBondContact O-N 3.41Å; M53-N57 WeakPolarHBondContact O-CA 3.42Å; M53-N57 PolarHBondContact O-N 2.95Å; M53-S58 VanDerWaalsContact CE-CA 3.43Å; M53-I59 HydrophobicContact CE-CG1 4.45Å; M53-I59 HydrophobicContact SD-CG1 4.08Å; M53-I280 HydrophobicContact CB-CG2 4.15Å; M53-I280 HydrophobicContact CG-CG2 4.14Å; M53-L281 VanDerWaalsContact C-CD2 3.49Å; M53-L281 HydrophobicContact CB-CD2 3.97Å; M53-L281 HydrophobicContact CG-CD2 3.69Å; M53-L281 HydrophobicContact CG-CG 4.04Å
54	E	92.9	Very high	93.2	Very high	115 Å²	115	18 Å²	18	54%	0.537	10%	0.095	S	C	.	.	H	α-helix	trans	-63.7	-32.7	175.9	-174	-177.2	-179.4	0	0	112.7	T50 I52 L281	T50-E54 VanDerWaalsContact O-CB 3.32Å; T50-E54 WeakPolarHBondContact O-CB 3.08Å; T50-E54 PolarHBondContact O-N 3.19Å; I52-E54 VanDerWaalsContact C-N 3.28Å; I52-E54 PolarHBondContact O-N 2.99Å; E54-L281 VanDerWaalsContact CA-CD2 3.46Å; E54-L281 HydrophobicContact CB-CD2 4.05Å
55	N	93.6	Very high	93.7	Very high	22 Å²	22	18 Å²	18	12%	0.118	9%	0.094	C	C	.	.	H	α-helix	trans	-87.2	-39.5	-177.8	-77.6	-78.2	0	0	0	113.1	G51 I52 M53 A217 K220 A221	G51-N55 PolarHBondContact O-N 2.77Å; G51-N55 PolarHBondContact O-ND2 3.23Å; I52-N55 PolarHBondContact O-N 3.21Å; M53-N55 VanDerWaalsContact C-N 3.29Å; M53-N55 PolarHBondContact O-N 3.41Å; N55-A217 VanDerWaalsContact O-CB 3.29Å; N55-A217 WeakPolarHBondContact O-CB 3.37Å; N55-K220 HydrophobicContact CB-CB 4.37Å; N55-K220 WeakPolarHBondContact OD1-CB 3.03Å; N55-K220 WeakPolarHBondContact OD1-CD 3.43Å; N55-K220 WeakPolarHBondContact OD1-CE 3.2Å; N55-K220 PolarHBondContact OD1-NZ 3.07Å; N55-A221 HydrophobicContact CB-CB 3.96Å
56	V	95.2	Very high	94	Very high	0 Å²	0	18 Å²	18	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-97.7	-10.2	-179.3	-63.7	0	0	0	0	114.3	I52 S58 A61 I65 S211 D212 A221	I52-V56 HydrophobicContact CG2-CG2 4.11Å; I52-V56 WeakPolarHBondContact O-CG2 3.5Å; I52-V56 PolarHBondContact O-N 2.87Å; V56-S58 PolarHBondContact O-N 3.08Å; V56-A61 HydrophobicContact CB-CB 3.89Å; V56-A61 HydrophobicContact CG2-CB 3.87Å; V56-I65 HydrophobicContact CG1-CG1 4.07Å; V56-S211 WeakPolarHBondContact O-CA 3.3Å; V56-D212 PolarHBondContact O-N 3.35Å; V56-A221 HydrophobicContact CG1-CB 3.77Å
57	N	92.7	Very high	94.4	Very high	76 Å²	76	20.8 Å²	20.8	41%	0.406	11%	0.111	S	C	.	.			trans	53.2	20.2	175.9	-159.2	38.8	0	0	0	115.8	M53	M53-N57 WeakPolarHBondContact O-CA 3.42Å; M53-N57 PolarHBondContact O-N 2.95Å
58	S	93.3	Very high	94.9	Very high	3 Å²	3	21.8 Å²	21.8	2%	0.021	12%	0.12	C	C	.	.			trans	-144.9	140.9	177.4	153.4	0	0	0	0	111.8	M53 V56 G60 A61 S62 A207 F208 S211	M53-S58 VanDerWaalsContact CE-CA 3.43Å; V56-S58 PolarHBondContact O-N 3.08Å; S58-G60 PolarHBondContact OG-N 2.96Å; S58-A61 PolarHBondContact OG-N 3.2Å; S58-A61 VanDerWaalsContact OG-N 3.07Å; S58-S62 VanDerWaalsContact O-CB 3.25Å; S58-S62 WeakPolarHBondContact O-CB 3.49Å; S58-S62 PolarHBondContact O-N 3.49Å; S58-A207 PolarHBondContact OG-O 3.33Å; S58-F208 WeakPolarHBondContact OG-CA 3.45Å; S58-S211 WeakPolarHBondContact CB-OG 3.46Å; S58-S211 PolarHBondContact OG-OG 2.94Å
59	I	93.7	Very high	95.1	Very high	10 Å²	10	21.8 Å²	21.8	5%	0.051	12%	0.12	C	C	.	.	H	α-helix	trans	-65.2	-47.4	175.6	-70.3	170.9	0	0	0	110.6	M53 S62 L63 G203 L204 A207 V272 P277	M53-I59 HydrophobicContact CE-CG1 4.45Å; M53-I59 HydrophobicContact SD-CG1 4.08Å; I59-S62 WeakPolarHBondContact O-CB 3.33Å; I59-S62 PolarHBondContact O-N 2.81Å; I59-L63 HydrophobicContact CG2-CD1 4.24Å; I59-L63 WeakPolarHBondContact O-CG 3.39Å; I59-L63 PolarHBondContact O-N 3.29Å; I59-G203 WeakPolarHBondContact CD1-O 3.14Å; I59-L204 HydrophobicContact CG2-CD2 4.37Å; I59-A207 PolarHBondContact N-O 3.45Å; I59-V272 HydrophobicContact CD1-CB 4.09Å; I59-V272 HydrophobicContact CD1-CG1 3.69Å; I59-V272 HydrophobicContact CG1-CG1 3.96Å; I59-V272 HydrophobicContact CG2-CB 4.47Å; I59-V272 HydrophobicContact CG2-CG1 3.86Å; I59-V272 HydrophobicContact CG2-CG2 4.34Å; I59-P277 HydrophobicContact CD1-CB 3.71Å; I59-P277 HydrophobicContact CD1-CG 3.61Å; I59-P277 HydrophobicContact CG1-CB 4.16Å
60	G	94.7	Very high	95.2	Very high	4 Å²	4	21.7 Å²	21.7	4%	0.041	12%	0.12	C	C	.	.	H	α-helix	trans	-61.3	-45.8	179.6	0	0	0	0	0	111.6	S58 S62 L63 I64 A207	S58-G60 PolarHBondContact OG-N 2.96Å; G60-S62 PolarHBondContact O-N 3.09Å; G60-L63 PolarHBondContact O-N 3.01Å; G60-I64 WeakPolarHBondContact O-CG1 3.4Å; G60-I64 PolarHBondContact O-N 3.45Å; G60-I64 VanDerWaalsContact O-N 3.11Å; G60-A207 PolarHBondContact N-O 2.76Å
61	A	96	Very high	95.4	Very high	0 Å²	0	25.2 Å²	25.2	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-62.2	-42.3	174.2	0	0	0	0	0	111.5	V56 S58 L63 I64 I65 W213	V56-A61 HydrophobicContact CB-CB 3.89Å; V56-A61 HydrophobicContact CG2-CB 3.87Å; S58-A61 PolarHBondContact OG-N 3.2Å; S58-A61 VanDerWaalsContact OG-N 3.07Å; A61-L63 PolarHBondContact O-N 3.21Å; A61-I64 WeakPolarHBondContact O-CB 3.35Å; A61-I64 PolarHBondContact O-N 2.9Å; A61-I64 VanDerWaalsContact O-N 3.14Å; A61-I65 WeakPolarHBondContact O-CG1 3.3Å; A61-I65 PolarHBondContact O-N 2.96Å; A61-W213 HydrophobicContact CB-CH2 3.99Å; A61-W213 HydrophobicContact CB-CZ2 3.73Å
62	S	96.2	Very high	95.7	Very high	8 Å²	8	25.4 Å²	25.4	6%	0.056	14%	0.139	C	C	.	.	H	α-helix	trans	-59.2	-44.6	177.6	176.7	0	0	0	0	112	I52 S58 I59 G60 I64 I65 W66	I52-S62 VanDerWaalsContact CG2-OG 3.23Å; I52-S62 WeakPolarHBondContact CG2-OG 3.45Å; S58-S62 VanDerWaalsContact O-CB 3.25Å; S58-S62 WeakPolarHBondContact O-CB 3.49Å; S58-S62 PolarHBondContact O-N 3.49Å; I59-S62 WeakPolarHBondContact O-CB 3.33Å; I59-S62 PolarHBondContact O-N 2.81Å; G60-S62 PolarHBondContact O-N 3.09Å; S62-I64 VanDerWaalsContact C-N 3.34Å; S62-I64 PolarHBondContact O-N 3.08Å; S62-I65 WeakPolarHBondContact O-CB 3.46Å; S62-I65 PolarHBondContact O-N 3.43Å; S62-W66 PolarHBondContact O-N 2.91Å
63	L	96.4	Very high	95.7	Very high	31 Å²	31	25.4 Å²	25.4	16%	0.162	14%	0.139	C	C	.	.	H	α-helix	trans	-62.9	-38.5	175.5	-67.2	175	0	0	0	112.3	I59 G60 A61 W66 V67 T265 N268 V269	I59-L63 HydrophobicContact CG2-CD1 4.24Å; I59-L63 WeakPolarHBondContact O-CG 3.39Å; I59-L63 PolarHBondContact O-N 3.29Å; G60-L63 PolarHBondContact O-N 3.01Å; A61-L63 PolarHBondContact O-N 3.21Å; L63-W66 PolarHBondContact O-N 3.47Å; L63-V67 WeakPolarHBondContact O-CG2 3.39Å; L63-V67 PolarHBondContact O-N 3.37Å; L63-V67 VanDerWaalsContact O-N 3.13Å; L63-T265 HydrophobicContact CD2-CG2 4.18Å; L63-N268 HydrophobicContact CD2-CB 3.78Å; L63-V269 HydrophobicContact CD1-CG2 4.06Å; L63-V269 HydrophobicContact CD2-CG2 3.94Å
64	I	97.3	Very high	95.8	Very high	76 Å²	76	26.9 Å²	26.9	39%	0.39	15%	0.146	S	C	.	.	H	α-helix	trans	-62.6	-43.2	173.7	-69.5	177	0	0	0	110.7	G60 A61 S62 W66 V67 A68 F208 W213	G60-I64 WeakPolarHBondContact O-CG1 3.4Å; G60-I64 PolarHBondContact O-N 3.45Å; G60-I64 VanDerWaalsContact O-N 3.11Å; A61-I64 WeakPolarHBondContact O-CB 3.35Å; A61-I64 PolarHBondContact O-N 2.9Å; A61-I64 VanDerWaalsContact O-N 3.14Å; S62-I64 VanDerWaalsContact C-N 3.34Å; S62-I64 PolarHBondContact O-N 3.08Å; I64-W66 PolarHBondContact O-N 2.99Å; I64-V67 PolarHBondContact O-N 2.93Å; I64-A68 VanDerWaalsContact O-CB 3.23Å; I64-A68 WeakPolarHBondContact O-CB 3.39Å; I64-A68 PolarHBondContact O-N 3.48Å; I64-F208 HydrophobicContact CD1-CE1 3.62Å; I64-F208 HydrophobicContact CD1-CZ 4.04Å; I64-F208 HydrophobicContact CG1-CE1 4.44Å; I64-W213 HydrophobicContact CB-CH2 4.37Å; I64-W213 HydrophobicContact CD1-CH2 3.93Å; I64-W213 HydrophobicContact CD1-CZ2 4.42Å; I64-W213 HydrophobicContact CG2-CH2 4.23Å
65	I	97.7	Very high	96	Very high	4 Å²	4	22.7 Å²	22.7	2%	0.021	13%	0.127	C	C	.	.	H	α-helix	trans	-60.2	-44.6	176.9	-65.1	-65.5	0	0	0	110.9	I52 V56 A61 S62 V67 A68 C69 I218 A221 F222	I52-I65 HydrophobicContact CD1-CG2 4.36Å; I52-I65 HydrophobicContact CG1-CG2 4.41Å; I52-I65 HydrophobicContact CG2-CB 4.07Å; I52-I65 HydrophobicContact CG2-CG1 4.46Å; I52-I65 HydrophobicContact CG2-CG2 4.08Å; V56-I65 HydrophobicContact CG1-CG1 4.07Å; A61-I65 WeakPolarHBondContact O-CG1 3.3Å; A61-I65 PolarHBondContact O-N 2.96Å; S62-I65 WeakPolarHBondContact O-CB 3.46Å; S62-I65 PolarHBondContact O-N 3.43Å; I65-V67 PolarHBondContact O-N 2.91Å; I65-A68 PolarHBondContact O-N 3.38Å; I65-C69 WeakPolarHBondContact O-CB 3.49Å; I65-C69 PolarHBondContact O-N 2.84Å; I65-C69 PolarHBondContact O-SG 3.44Å; I65-I218 HydrophobicContact CD1-CG2 4.15Å; I65-A221 HydrophobicContact CD1-CB 4.44Å; I65-A221 HydrophobicContact CG1-CB 4.27Å; I65-A221 HydrophobicContact CG2-CB 4.2Å; I65-F222 HydrophobicContact CD1-CD2 3.8Å; I65-F222 HydrophobicContact CD1-CE2 3.94Å; I65-F222 HydrophobicContact CG2-CD2 4.42Å
66	W	97.5	Very high	96	Very high	0 Å²	0	21.7 Å²	21.7	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-55.5	-51.4	175.4	-82.2	106.6	0	0	0	112.3	I45 P49 I52 S62 L63 I64 A68 C69 G70 A228 Y229 Y264 N268	I45-W66 HydrophobicContact CD1-CH2 3.6Å; I45-W66 HydrophobicContact CD1-CZ2 3.9Å; I45-W66 HydrophobicContact CD1-CZ3 4.11Å; P49-W66 HydrophobicContact CG-CZ2 4.24Å; I52-W66 HydrophobicContact CD1-CD2 3.99Å; I52-W66 HydrophobicContact CD1-CG 4.31Å; I52-W66 HydrophobicContact CD1-CH2 4.45Å; I52-W66 HydrophobicContact CD1-CZ2 3.68Å; S62-W66 PolarHBondContact O-N 2.91Å; L63-W66 PolarHBondContact O-N 3.47Å; I64-W66 PolarHBondContact O-N 2.99Å; W66-A68 VanDerWaalsContact C-N 3.35Å; W66-A68 PolarHBondContact O-N 3.25Å; W66-C69 PolarHBondContact O-N 2.96Å; W66-G70 PolarHBondContact O-N 3.32Å; W66-A228 HydrophobicContact CH2-CB 3.64Å; W66-A228 HydrophobicContact CZ3-CB 3.65Å; W66-Y229 AromaticContact CE3-CE2 3.61Å; W66-Y229 HydrophobicContact CE3-CE2 3.61Å; W66-Y229 HydrophobicContact CZ3-CD2 4.49Å; W66-Y229 AromaticContact CZ3-CE2 3.91Å; W66-Y229 HydrophobicContact CZ3-CE2 3.91Å; W66-Y229 PolarHBondContact O-OH 3.28Å; W66-Y264 AromaticContact CE3-CD2 3.8Å; W66-Y264 HydrophobicContact CE3-CD2 3.8Å; W66-Y264 HydrophobicContact CE3-CG 4.12Å; W66-Y264 HydrophobicContact CH2-CD2 4.35Å; W66-Y264 AromaticContact CZ3-CD2 3.34Å; W66-Y264 HydrophobicContact CZ3-CD2 3.34Å; W66-Y264 AromaticContact CZ3-CE2 3.97Å; W66-Y264 HydrophobicContact CZ3-CE2 3.97Å; W66-Y264 AromaticContact CZ3-CG 3.78Å; W66-Y264 HydrophobicContact CZ3-CG 3.78Å; W66-N268 WeakPolarHBondContact CZ2-ND2 3.15Å; W66-N268 VanDerWaalsContact NE1-CG 3.25Å; W66-N268 PolarHBondContact NE1-ND2 2.74Å; W66-N268 VanDerWaalsContact NE1-ND2 3.12Å; W66-N268 PolarHBondContact NE1-OD1 3.5Å
67	V	98.1	Very high	96	Very high	59 Å²	59	21.7 Å²	21.7	36%	0.358	12%	0.121	S	C	.	.	H	α-helix	trans	-62.3	-43.7	178.8	175.5	0	0	0	0	111.1	L63 I64 I65 G70 L71 T265	L63-V67 WeakPolarHBondContact O-CG2 3.39Å; L63-V67 PolarHBondContact O-N 3.37Å; L63-V67 VanDerWaalsContact O-N 3.13Å; I64-V67 PolarHBondContact O-N 2.93Å; I65-V67 PolarHBondContact O-N 2.91Å; V67-G70 PolarHBondContact O-N 3.32Å; V67-L71 HydrophobicContact CG1-CD1 4.13Å; V67-L71 HydrophobicContact CG1-CG 4.44Å; V67-L71 WeakPolarHBondContact O-CG 3.4Å; V67-L71 PolarHBondContact O-N 3.38Å; V67-T265 HydrophobicContact CG2-CG2 4.21Å
68	A	97.8	Very high	96.1	Very high	30 Å²	30	20.4 Å²	20.4	25%	0.248	11%	0.111	C	C	.	.	H	α-helix	trans	-65.3	-41.2	-179.3	0	0	0	0	0	112.2	I64 I65 W66 G70 L71 F72 F222	I64-A68 VanDerWaalsContact O-CB 3.23Å; I64-A68 WeakPolarHBondContact O-CB 3.39Å; I64-A68 PolarHBondContact O-N 3.48Å; I65-A68 PolarHBondContact O-N 3.38Å; W66-A68 VanDerWaalsContact C-N 3.35Å; W66-A68 PolarHBondContact O-N 3.25Å; A68-G70 VanDerWaalsContact C-N 3.32Å; A68-G70 PolarHBondContact O-N 3.34Å; A68-L71 PolarHBondContact O-N 3.06Å; A68-F72 VanDerWaalsContact O-CB 3.27Å; A68-F72 WeakPolarHBondContact O-CB 3.22Å; A68-F72 PolarHBondContact O-N 3.11Å; A68-F222 HydrophobicContact CB-CE2 3.92Å; A68-F222 HydrophobicContact CB-CZ 3.59Å
69	C	97.3	Very high	96.1	Very high	0 Å²	0	20.2 Å²	20.2	0%	0	11%	0.11	C	C	.	.	H	α-helix	trans	-61.2	-40	173	-72.2	0	0	0	0	111.9	I65 W66 S73 L226 Y229	I65-C69 WeakPolarHBondContact O-CB 3.49Å; I65-C69 PolarHBondContact O-N 2.84Å; I65-C69 PolarHBondContact O-SG 3.44Å; W66-C69 PolarHBondContact O-N 2.96Å; C69-S73 WeakPolarHBondContact O-CB 3.27Å; C69-S73 PolarHBondContact O-N 3.34Å; C69-S73 PolarHBondContact O-OG 3.47Å; C69-L226 HydrophobicContact CB-CD2 3.79Å; C69-L226 HydrophobicContact CB-CG 4.29Å; C69-Y229 HydrophobicContact CB-CD2 3.65Å; C69-Y229 HydrophobicContact CB-CE2 3.63Å
70	G	96.8	Very high	96.1	Very high	1 Å²	1	19.8 Å²	19.8	1%	0.01	11%	0.108	C	C	.	.	H	α-helix	trans	-64	-47.5	176	0	0	0	0	0	113.3	W66 V67 A68 S73 M74 Y229 T261	W66-G70 PolarHBondContact O-N 3.32Å; V67-G70 PolarHBondContact O-N 3.32Å; A68-G70 VanDerWaalsContact C-N 3.32Å; A68-G70 PolarHBondContact O-N 3.34Å; G70-S73 PolarHBondContact O-N 3.46Å; G70-M74 PolarHBondContact O-N 3.35Å; G70-Y229 VanDerWaalsContact CA-CE1 3.41Å; G70-T261 VanDerWaalsContact CA-OG1 3.28Å; G70-T261 WeakPolarHBondContact CA-OG1 3.17Å
71	L	97.1	Very high	96	Very high	82 Å²	82	19.6 Å²	19.6	43%	0.429	11%	0.106	S	C	.	.	H	α-helix	trans	-63.5	-44.2	175.7	-68.6	175.9	0	0	0	111.8	V67 A68 S73 M74 L75	V67-L71 HydrophobicContact CG1-CD1 4.13Å; V67-L71 HydrophobicContact CG1-CG 4.44Å; V67-L71 WeakPolarHBondContact O-CG 3.4Å; V67-L71 PolarHBondContact O-N 3.38Å; A68-L71 PolarHBondContact O-N 3.06Å; L71-S73 VanDerWaalsContact C-N 3.34Å; L71-S73 PolarHBondContact O-N 3.12Å; L71-M74 HydrophobicContact CD2-CE 3.97Å; L71-M74 WeakPolarHBondContact O-CB 3.49Å; L71-M74 PolarHBondContact O-N 2.87Å; L71-L75 WeakPolarHBondContact O-CG 3.49Å; L71-L75 PolarHBondContact O-N 3.02Å
72	F	96.8	Very high	95.9	Very high	4 Å²	4	19.6 Å²	19.6	2%	0.018	11%	0.106	C	C	.	.	H	α-helix	trans	-58.3	-47.4	175.4	178.4	-101.4	0	0	0	111.2	A68 M74 L75 G76 F222 L226 W380 Y414 I417	A68-F72 VanDerWaalsContact O-CB 3.27Å; A68-F72 WeakPolarHBondContact O-CB 3.22Å; A68-F72 PolarHBondContact O-N 3.11Å; F72-M74 VanDerWaalsContact C-N 3.31Å; F72-M74 PolarHBondContact O-N 3.2Å; F72-L75 PolarHBondContact O-N 2.93Å; F72-G76 PolarHBondContact O-N 2.94Å; F72-F222 HydrophobicContact CB-CE1 4.25Å; F72-F222 HydrophobicContact CG-CE1 4.44Å; F72-L226 HydrophobicContact CD1-CD1 3.89Å; F72-L226 HydrophobicContact CD1-CD2 3.57Å; F72-L226 HydrophobicContact CD1-CG 4.39Å; F72-L226 HydrophobicContact CE1-CD1 3.77Å; F72-L226 HydrophobicContact CE1-CD2 4.21Å; F72-W380 HydrophobicContact CE1-CE3 4.09Å; F72-W380 HydrophobicContact CE1-CZ3 4.42Å; F72-Y414 AromaticContact CD1-CE2 3.74Å; F72-Y414 HydrophobicContact CD1-CE2 3.74Å; F72-Y414 AromaticContact CD2-CD2 3.76Å; F72-Y414 HydrophobicContact CD2-CD2 3.76Å; F72-Y414 AromaticContact CD2-CE2 3.81Å; F72-Y414 HydrophobicContact CD2-CE2 3.81Å; F72-Y414 HydrophobicContact CD2-CG 4.47Å; F72-Y414 HydrophobicContact CE1-CD2 4.31Å; F72-Y414 HydrophobicContact CE1-CE1 4.29Å; F72-Y414 AromaticContact CE1-CE2 3.44Å; F72-Y414 HydrophobicContact CE1-CE2 3.44Å; F72-Y414 VanDerWaalsContact CE1-CE2 3.44Å; F72-Y414 AromaticContact CE1-CZ 3.43Å; F72-Y414 VanDerWaalsContact CE1-CZ 3.43Å; F72-Y414 VanDerWaalsContact CE1-OH 3.27Å; F72-Y414 WeakPolarHBondContact CE1-OH 3.28Å; F72-Y414 HydrophobicContact CE2-CD1 4.17Å; F72-Y414 AromaticContact CE2-CD2 3.46Å; F72-Y414 HydrophobicContact CE2-CD2 3.46Å; F72-Y414 VanDerWaalsContact CE2-CD2 3.46Å; F72-Y414 HydrophobicContact CE2-CE1 4.17Å; F72-Y414 AromaticContact CE2-CE2 3.46Å; F72-Y414 HydrophobicContact CE2-CE2 3.46Å; F72-Y414 VanDerWaalsContact CE2-CE2 3.46Å; F72-Y414 AromaticContact CE2-CG 3.83Å; F72-Y414 HydrophobicContact CE2-CG 3.83Å; F72-Y414 AromaticContact CE2-CZ 3.83Å; F72-Y414 HydrophobicContact CG-CD2 4.29Å; F72-Y414 AromaticContact CG-CE2 3.95Å; F72-Y414 HydrophobicContact CG-CE2 3.95Å; F72-Y414 HydrophobicContact CZ-CD1 4.12Å; F72-Y414 AromaticContact CZ-CD2 3.8Å; F72-Y414 HydrophobicContact CZ-CD2 3.8Å; F72-Y414 AromaticContact CZ-CE1 3.67Å; F72-Y414 HydrophobicContact CZ-CE1 3.67Å; F72-Y414 AromaticContact CZ-CE2 3.3Å; F72-Y414 HydrophobicContact CZ-CE2 3.3Å; F72-Y414 HydrophobicContact CZ-CG 4.19Å; F72-Y414 AromaticContact CZ-CZ 3.23Å; F72-Y414 WeakPolarHBondContact O-CD2 3.4Å; F72-Y414 WeakPolarHBondContact O-CE2 3.22Å; F72-I417 HydrophobicContact CD2-CB 3.99Å; F72-I417 HydrophobicContact CD2-CD1 4.01Å; F72-I417 HydrophobicContact CD2-CG2 3.61Å; F72-I417 HydrophobicContact CE2-CB 3.68Å; F72-I417 HydrophobicContact CE2-CG2 3.46Å; F72-I417 VanDerWaalsContact CE2-CG2 3.46Å; F72-I417 HydrophobicContact CZ-CG2 4.26Å
73	S	95.6	Very high	95.7	Very high	0 Å²	0	19.2 Å²	19.2	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-59.8	-40.4	177.2	-61.4	0	0	0	0	112.3	C69 G70 L71 G76 A77 Y229	C69-S73 WeakPolarHBondContact O-CB 3.27Å; C69-S73 PolarHBondContact O-N 3.34Å; C69-S73 PolarHBondContact O-OG 3.47Å; G70-S73 PolarHBondContact O-N 3.46Å; L71-S73 VanDerWaalsContact C-N 3.34Å; L71-S73 PolarHBondContact O-N 3.12Å; S73-G76 PolarHBondContact O-N 2.9Å; S73-A77 VanDerWaalsContact O-CB 3.27Å; S73-A77 WeakPolarHBondContact O-CB 3.41Å; S73-A77 PolarHBondContact O-N 3.14Å; S73-Y229 WeakPolarHBondContact OG-CB 3.37Å
74	M	95.4	Very high	95.3	Very high	39 Å²	39	17.8 Å²	17.8	19%	0.192	10%	0.096	C	C	.	.	H	α-helix	trans	-62.3	-43	175.9	-174	179.3	63.3	0	0	112.3	G70 L71 F72 A77 Y78 C257 L258	G70-M74 PolarHBondContact O-N 3.35Å; L71-M74 HydrophobicContact CD2-CE 3.97Å; L71-M74 WeakPolarHBondContact O-CB 3.49Å; L71-M74 PolarHBondContact O-N 2.87Å; F72-M74 VanDerWaalsContact C-N 3.31Å; F72-M74 PolarHBondContact O-N 3.2Å; M74-A77 PolarHBondContact O-N 3.08Å; M74-Y78 WeakPolarHBondContact O-CB 3.34Å; M74-Y78 PolarHBondContact O-N 2.94Å; M74-C257 HydrophobicContact CB-CB 3.78Å; M74-C257 HydrophobicContact CG-CB 4.03Å; M74-L258 HydrophobicContact SD-CD2 4.22Å; M74-L258 HydrophobicContact SD-CG 4.24Å
75	L	96.2	Very high	94.9	Very high	28 Å²	28	14.2 Å²	14.2	15%	0.147	8%	0.078	C	C	.	.	H	α-helix	trans	-61.8	-45.4	176.9	-67	175.1	0	0	0	111.3	L71 F72 Y78 C79 F410 I413 Y414	L71-L75 WeakPolarHBondContact O-CG 3.49Å; L71-L75 PolarHBondContact O-N 3.02Å; F72-L75 PolarHBondContact O-N 2.93Å; L75-Y78 PolarHBondContact O-N 2.67Å; L75-C79 PolarHBondContact O-N 2.98Å; L75-C79 VanDerWaalsContact O-N 3.12Å; L75-C79 PolarHBondContact O-SG 2.91Å; L75-F410 HydrophobicContact CD2-CB 3.96Å; L75-F410 HydrophobicContact CD2-CD1 3.71Å; L75-F410 HydrophobicContact CD2-CD2 3.79Å; L75-F410 HydrophobicContact CD2-CE1 4.09Å; L75-F410 HydrophobicContact CD2-CE2 4.16Å; L75-F410 HydrophobicContact CD2-CG 3.56Å; L75-F410 HydrophobicContact CD2-CZ 4.3Å; L75-I413 HydrophobicContact CD1-CG2 3.94Å; L75-Y414 HydrophobicContact CB-CD2 4.1Å
76	G	94.7	Very high	94.6	Very high	0 Å²	0	14.5 Å²	14.5	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-62.2	-47.1	176.8	0	0	0	0	0	112.1	F72 S73 Y78 C79 Y80 W232 Y414	F72-G76 PolarHBondContact O-N 2.94Å; S73-G76 PolarHBondContact O-N 2.9Å; G76-Y78 VanDerWaalsContact C-N 3.34Å; G76-Y78 PolarHBondContact O-N 3.44Å; G76-C79 WeakPolarHBondContact O-CB 3.32Å; G76-C79 PolarHBondContact O-N 3.13Å; G76-Y80 WeakPolarHBondContact O-CD2 3.47Å; G76-Y80 PolarHBondContact O-N 3.03Å; G76-W232 VanDerWaalsContact C-CH2 3.49Å; G76-Y414 VanDerWaalsContact CA-CD2 3.49Å; G76-Y414 VanDerWaalsContact N-CD2 3.33Å
77	A	94	Very high	94	Very high	0 Å²	0	15.3 Å²	15.3	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-59.4	-43	177.8	0	0	0	0	0	112.5	S73 M74 C79 Y80 A81 W232 I253	S73-A77 VanDerWaalsContact O-CB 3.27Å; S73-A77 WeakPolarHBondContact O-CB 3.41Å; S73-A77 PolarHBondContact O-N 3.14Å; M74-A77 PolarHBondContact O-N 3.08Å; A77-C79 VanDerWaalsContact C-N 3.34Å; A77-C79 PolarHBondContact O-N 3.4Å; A77-Y80 WeakPolarHBondContact O-CB 3.31Å; A77-Y80 PolarHBondContact O-N 2.9Å; A77-A81 PolarHBondContact O-N 3.47Å; A77-W232 HydrophobicContact CB-CB 4.48Å; A77-W232 HydrophobicContact CB-CD2 3.76Å; A77-W232 HydrophobicContact CB-CE3 3.37Å; A77-W232 HydrophobicContact CB-CG 4.24Å; A77-W232 HydrophobicContact CB-CZ3 3.9Å; A77-I253 HydrophobicContact CB-CB 4.4Å; A77-I253 HydrophobicContact CB-CD1 4.34Å; A77-I253 HydrophobicContact CB-CG1 4.22Å; A77-I253 HydrophobicContact CB-CG2 3.35Å; A77-I253 WeakPolarHBondContact O-CD1 3.5Å
78	Y	95.1	Very high	92.7	Very high	49 Å²	49	17.9 Å²	17.9	19%	0.192	9%	0.091	C	C	.	.	H	α-helix	trans	-65.6	-37.6	177.6	-154.2	-80	0	0	0	112.3	M74 L75 G76 Y80 A81 E82 P250 I254 V404 A406 F410	M74-Y78 WeakPolarHBondContact O-CB 3.34Å; M74-Y78 PolarHBondContact O-N 2.94Å; L75-Y78 PolarHBondContact O-N 2.67Å; G76-Y78 VanDerWaalsContact C-N 3.34Å; G76-Y78 PolarHBondContact O-N 3.44Å; Y78-Y80 VanDerWaalsContact C-N 3.32Å; Y78-A81 WeakPolarHBondContact O-CB 3.41Å; Y78-A81 PolarHBondContact O-N 3.36Å; Y78-E82 PolarHBondContact O-N 3Å; Y78-P250 HydrophobicContact CE2-CB 3.76Å; Y78-I254 HydrophobicContact CD2-CD1 4.17Å; Y78-I254 HydrophobicContact CD2-CG1 4.22Å; Y78-I254 HydrophobicContact CE2-CD1 3.8Å; Y78-I254 HydrophobicContact CE2-CG1 4.34Å; Y78-V404 HydrophobicContact CE1-CG1 4.27Å; Y78-A406 HydrophobicContact CD1-CB 3.76Å; Y78-A406 HydrophobicContact CE1-CB 4.21Å; Y78-F410 HydrophobicContact CD1-CD2 4.34Å; Y78-F410 HydrophobicContact CG-CD2 4.47Å
79	C	94.8	Very high	91.4	Very high	0 Å²	0	23.6 Å²	23.6	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-64.2	-39	173.5	-66.7	0	0	0	0	111.7	L75 G76 A77 A81 E82 L83 V387 V390	L75-C79 PolarHBondContact O-N 2.98Å; L75-C79 VanDerWaalsContact O-N 3.12Å; L75-C79 PolarHBondContact O-SG 2.91Å; G76-C79 WeakPolarHBondContact O-CB 3.32Å; G76-C79 PolarHBondContact O-N 3.13Å; A77-C79 VanDerWaalsContact C-N 3.34Å; A77-C79 PolarHBondContact O-N 3.4Å; C79-A81 VanDerWaalsContact C-N 3.34Å; C79-E82 WeakPolarHBondContact O-CB 3.38Å; C79-E82 PolarHBondContact O-N 3.2Å; C79-L83 PolarHBondContact O-N 2.92Å; C79-V387 HydrophobicContact CB-CG1 3.88Å; C79-V387 HydrophobicContact CB-CG2 4.21Å; C79-V390 HydrophobicContact CB-CG2 4.11Å
80	Y	92.7	Very high	89.8	Confident	0 Å²	0	25.5 Å²	25.5	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-65.9	-34.1	174.2	-95.6	-116.5	0	0	0	113.1	G76 A77 Y78 E82 L83 G84 D93 Y96 W232 N233 N236 I383 C386 V387	G76-Y80 WeakPolarHBondContact O-CD2 3.47Å; G76-Y80 PolarHBondContact O-N 3.03Å; A77-Y80 WeakPolarHBondContact O-CB 3.31Å; A77-Y80 PolarHBondContact O-N 2.9Å; Y78-Y80 VanDerWaalsContact C-N 3.32Å; Y80-E82 PolarHBondContact O-N 3.44Å; Y80-L83 PolarHBondContact O-N 3.32Å; Y80-L83 VanDerWaalsContact O-N 3.09Å; Y80-G84 PolarHBondContact O-N 3.33Å; Y80-D93 HydrophobicContact CE1-CB 4.41Å; Y80-D93 WeakPolarHBondContact CE1-OD1 3.4Å; Y80-D93 PolarHBondContact OH-OD2 3.33Å; Y80-Y96 HydrophobicContact CD1-CE2 4.04Å; Y80-Y96 HydrophobicContact CE1-CD2 4.49Å; Y80-Y96 HydrophobicContact CE1-CE2 4.27Å; Y80-W232 HydrophobicContact CD1-CZ3 4.01Å; Y80-W232 AromaticContact CD2-CH2 3.66Å; Y80-W232 HydrophobicContact CD2-CH2 3.66Å; Y80-W232 AromaticContact CD2-CZ3 3.75Å; Y80-W232 HydrophobicContact CD2-CZ3 3.75Å; Y80-W232 HydrophobicContact CE1-CZ3 4.44Å; Y80-W232 AromaticContact CE2-CH2 3.83Å; Y80-W232 HydrophobicContact CE2-CH2 3.83Å; Y80-W232 HydrophobicContact CE2-CZ3 4.25Å; Y80-W232 HydrophobicContact CG-CH2 4.02Å; Y80-W232 AromaticContact CG-CZ3 3.6Å; Y80-W232 HydrophobicContact CG-CZ3 3.6Å; Y80-N233 HydrophobicContact CD1-CB 4.2Å; Y80-N233 HydrophobicContact CE1-CB 4.05Å; Y80-N236 WeakPolarHBondContact CB-ND2 3.4Å; Y80-N236 PolarHBondContact O-OD1 3.42Å; Y80-I383 HydrophobicContact CE2-CG2 3.87Å; Y80-C386 HydrophobicContact CE2-CB 3.77Å; Y80-C386 WeakPolarHBondContact OH-CB 3.48Å; Y80-V387 HydrophobicContact CD2-CG2 4.03Å; Y80-V387 HydrophobicContact CE2-CG2 3.86Å
81	A	92.4	Very high	88.3	Confident	0 Å²	0	26 Å²	26	0%	0	13%	0.125	C	C	.	.	H	α-helix	trans	-60.3	-37.3	175.7	0	0	0	0	0	112.2	A77 Y78 C79 T85 L249 I253 V404	A77-A81 PolarHBondContact O-N 3.47Å; Y78-A81 WeakPolarHBondContact O-CB 3.41Å; Y78-A81 PolarHBondContact O-N 3.36Å; C79-A81 VanDerWaalsContact C-N 3.34Å; A81-T85 WeakPolarHBondContact O-CB 3.45Å; A81-T85 WeakPolarHBondContact O-CG2 3.19Å; A81-T85 PolarHBondContact O-N 2.96Å; A81-T85 VanDerWaalsContact O-N 3.08Å; A81-T85 PolarHBondContact O-OG1 3.15Å; A81-L249 HydrophobicContact CB-CD2 3.85Å; A81-L249 HydrophobicContact CB-CG 3.9Å; A81-I253 HydrophobicContact CB-CD1 3.66Å; A81-V404 HydrophobicContact CB-CG1 4.2Å
82	E	93.7	Very high	87.4	Confident	1 Å²	1	22.1 Å²	22.1	1%	0.005	10%	0.104	C	C	.	.	H	α-helix	trans	-64.4	-48	171.3	170.1	171.9	170.7	0	0	111.7	Y78 C79 Y80 G84 T85 M86 R394 R402 V404 A406	Y78-E82 PolarHBondContact O-N 3Å; C79-E82 WeakPolarHBondContact O-CB 3.38Å; C79-E82 PolarHBondContact O-N 3.2Å; Y80-E82 PolarHBondContact O-N 3.44Å; E82-G84 PolarHBondContact O-N 3.4Å; E82-T85 PolarHBondContact O-N 3.48Å; E82-T85 PolarHBondContact O-OG1 2.98Å; E82-M86 VanDerWaalsContact O-CB 3.24Å; E82-M86 WeakPolarHBondContact O-CB 3.44Å; E82-M86 PolarHBondContact O-N 3.07Å; E82-R394 IonicContact OE1-CZ 3.71Å; E82-R394 IonicContact OE1-NH1 3.14Å; E82-R394 PolarHBondContact OE1-NH1 3.47Å; E82-R394 IonicContact OE1-NH2 3.89Å; E82-R394 PolarHBondContact OE1-NH2 3.41Å; E82-R394 IonicContact OE2-CZ 2.7Å; E82-R394 IonicContact OE2-NH1 3.6Å; E82-R394 IonicContact OE2-NH2 2.78Å; E82-R394 PolarHBondContact OE2-NH2 3.45Å; E82-R402 VanDerWaalsContact OE1-CD 3.32Å; E82-R402 WeakPolarHBondContact OE1-CD 3.31Å; E82-R402 IonicContact OE1-NE 3.66Å; E82-R402 PolarHBondContact OE1-NE 3.14Å; E82-V404 WeakPolarHBondContact CG-O 3.37Å; E82-A406 HydrophobicContact CB-CB 4.3Å; E82-A406 WeakPolarHBondContact OE2-CB 3.48Å; E82-A406 PolarHBondContact OE2-N 2.93Å
83	L	92.4	Very high	86.8	Confident	0 Å²	0	22 Å²	22	0%	0	10%	0.104	C	C	.	.	H	α-helix	trans	-61.6	-44.7	-179.7	-66.7	175.9	0	0	0	111.8	C79 Y80 T85 M86 I87 Y96 C386 I389 V390 F393	C79-L83 PolarHBondContact O-N 2.92Å; Y80-L83 PolarHBondContact O-N 3.32Å; Y80-L83 VanDerWaalsContact O-N 3.09Å; L83-T85 PolarHBondContact O-N 3.43Å; L83-M86 PolarHBondContact O-N 3.39Å; L83-I87 PolarHBondContact O-N 3.23Å; L83-Y96 HydrophobicContact CB-CD1 4.25Å; L83-Y96 HydrophobicContact CB-CD2 3.9Å; L83-Y96 HydrophobicContact CB-CE1 4.25Å; L83-Y96 HydrophobicContact CB-CE2 3.89Å; L83-Y96 HydrophobicContact CB-CG 4.11Å; L83-Y96 HydrophobicContact CD1-CD2 3.95Å; L83-Y96 HydrophobicContact CD1-CG 4.33Å; L83-C386 WeakPolarHBondContact CD1-O 3.3Å; L83-I389 HydrophobicContact CD1-CB 4.49Å; L83-I389 HydrophobicContact CD2-CB 4.28Å; L83-I389 HydrophobicContact CD2-CG2 3.87Å; L83-V390 HydrophobicContact CD1-CG2 4.02Å; L83-V390 HydrophobicContact CD2-CG2 3.82Å; L83-V390 HydrophobicContact CG-CG2 3.71Å; L83-F393 HydrophobicContact CD2-CD2 4.13Å; L83-F393 HydrophobicContact CD2-CE2 4.31Å
84	G	88.4	Confident	86.3	Confident	0 Å²	0	22.6 Å²	22.6	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-63.8	-39.4	178.1	0	0	0	0	0	113.1	Y80 E82 M86 I87 Y96 I239	Y80-G84 PolarHBondContact O-N 3.33Å; E82-G84 PolarHBondContact O-N 3.4Å; G84-M86 VanDerWaalsContact C-N 3.33Å; G84-I87 CarbonylContact O-C 3.11Å; G84-Y96 WeakPolarHBondContact CA-OH 3.25Å; G84-Y96 PolarHBondContact N-OH 2.91Å; G84-I239 VanDerWaalsContact C-CD1 3.41Å; G84-I239 WeakPolarHBondContact O-CD1 3.29Å
85	T	89.5	Confident	85.8	Confident	2 Å²	2	21.1 Å²	21.1	1%	0.012	10%	0.099	C	C	.	.	H	α-helix	trans	-80.2	-13.8	176.6	58.6	0	0	0	0	113.6	A81 E82 L83 H88 I239 P245 L249 P403 V404	A81-T85 WeakPolarHBondContact O-CB 3.45Å; A81-T85 WeakPolarHBondContact O-CG2 3.19Å; A81-T85 PolarHBondContact O-N 2.96Å; A81-T85 VanDerWaalsContact O-N 3.08Å; A81-T85 PolarHBondContact O-OG1 3.15Å; E82-T85 PolarHBondContact O-N 3.48Å; E82-T85 PolarHBondContact O-OG1 2.98Å; L83-T85 PolarHBondContact O-N 3.43Å; T85-H88 PolarHBondContact O-CE1 3.28Å; T85-H88 PolarHBondContact O-ND1 2.83Å; T85-I239 HydrophobicContact CG2-CD1 3.83Å; T85-P245 HydrophobicContact CG2-CB 4.28Å; T85-L249 HydrophobicContact CG2-CD2 4.12Å; T85-P403 WeakPolarHBondContact O-CD 3.35Å; T85-P403 WeakPolarHBondContact O-CG 3.31Å; T85-V404 HydrophobicContact CG2-CB 4.38Å; T85-V404 HydrophobicContact CG2-CG2 3.86Å; T85-V404 WeakPolarHBondContact OG1-CB 3.26Å; T85-V404 PolarHBondContact OG1-N 3.11Å
86	M	90.3	Very high	85.5	Confident	10 Å²	10	19.9 Å²	19.9	5%	0.049	9%	0.092	C	C	.	.	H	α-helix	trans	-88	-39.8	173.6	-174.8	171.2	160.2	0	0	111.7	E82 L83 G84 F393 K397 H400 R402	E82-M86 VanDerWaalsContact O-CB 3.24Å; E82-M86 WeakPolarHBondContact O-CB 3.44Å; E82-M86 PolarHBondContact O-N 3.07Å; L83-M86 PolarHBondContact O-N 3.39Å; G84-M86 VanDerWaalsContact C-N 3.33Å; M86-F393 HydrophobicContact CE-CB 4.32Å; M86-F393 HydrophobicContact CE-CD2 3.75Å; M86-F393 HydrophobicContact CE-CE2 4.34Å; M86-F393 HydrophobicContact CE-CG 4.2Å; M86-F393 HydrophobicContact SD-CD2 3.99Å; M86-K397 HydrophobicContact CE-CB 3.79Å; M86-K397 HydrophobicContact CE-CD 3.69Å; M86-K397 HydrophobicContact CE-CG 4.36Å; M86-H400 HydrophobicContact CE-CB 3.69Å; M86-R402 HydrophobicContact SD-CG 4.18Å
87	I	84.3	Confident	85.5	Confident	17 Å²	17	20 Å²	20	9%	0.087	9%	0.093	C	C	.	.	S	Bend	trans	-111.3	92.8	179.7	-59.4	169.7	0	0	0	108.8	L83 G84 R89 I95 Y96 E99 F393	L83-I87 PolarHBondContact O-N 3.23Å; G84-I87 CarbonylContact O-C 3.11Å; I87-R89 HydrophobicContact CG2-CB 4.37Å; I87-R89 PolarHBondContact O-N 3.32Å; I87-I95 HydrophobicContact CG2-CG1 4.49Å; I87-I95 HydrophobicContact CG2-CG2 4.19Å; I87-Y96 HydrophobicContact CB-CD1 4.15Å; I87-Y96 HydrophobicContact CB-CE1 4.13Å; I87-Y96 HydrophobicContact CD1-CD1 3.84Å; I87-Y96 HydrophobicContact CG2-CD1 4.45Å; I87-E99 HydrophobicContact CD1-CB 4.04Å; I87-E99 HydrophobicContact CD1-CG 3.93Å; I87-F393 HydrophobicContact CD1-CE2 3.74Å; I87-F393 HydrophobicContact CD1-CZ 4.24Å
88	H	72.3	Confident	85.3	Confident	112 Å²	112	22.9 Å²	22.9	52%	0.519	11%	0.105	S	C	.	.			trans	-79.4	69.1	176.9	-69.1	84.9	0	0	0	110.8	T85	T85-H88 PolarHBondContact O-CE1 3.28Å; T85-H88 PolarHBondContact O-ND1 2.83Å
89	R	69.8	Low	85	Confident	150 Å²	150	24.4 Å²	24.4	57%	0.566	11%	0.113	S	C	*	.			trans	-135.7	130.8	169.4	-69.6	-171.9	-179.8	178.1	1.1	110	I87 G91 I95 E240	I87-R89 HydrophobicContact CG2-CB 4.37Å; I87-R89 PolarHBondContact O-N 3.32Å; R89-G91 PolarHBondContact O-N 3.31Å; R89-I95 HydrophobicContact CB-CG1 4.11Å; R89-I95 HydrophobicContact CB-CG2 4.46Å; R89-E240 WeakPolarHBondContact CA-OE1 3.04Å
90	S	63.2	Low	84.9	Confident	41 Å²	41	25.6 Å²	25.6	29%	0.287	12%	0.123	S	C	.	.	T	Hydrogen-bonded Turn	trans	-55.5	117.1	166.9	-77.5	0	0	0	0	110.6	E240 V327	S90-E240 PolarHBondContact N-OE1 3.07Å; S90-E240 PolarHBondContact OG-OE1 3.18Å; S90-E240 PolarHBondContact OG-OE2 3.47Å; S90-V327 VanDerWaalsContact O-CG1 3.25Å; S90-V327 WeakPolarHBondContact O-CG1 3.39Å
91	G	66.6	Low	85	Confident	11 Å²	11	29.2 Å²	29.2	11%	0.113	14%	0.139	C	C	.	.	T	Hydrogen-bonded Turn	trans	157.7	-14.6	-178.8	0	0	0	0	0	115.6	R89	R89-G91 PolarHBondContact O-N 3.31Å
92	G	77.3	Confident	84.9	Confident	0 Å²	0	30.2 Å²	30.2	0%	0	15%	0.149	C	C	.	.	T	Hydrogen-bonded Turn	trans	57.8	-136	173.4	0	0	0	0	0	113.3	Y94 I95 Y96	G92-Y94 PolarHBondContact O-N 3.32Å; G92-Y94 VanDerWaalsContact O-N 3.11Å; G92-I95 VanDerWaalsContact O-CG2 3.26Å; G92-I95 WeakPolarHBondContact O-CG2 3.17Å; G92-I95 PolarHBondContact O-N 2.99Å; G92-I95 VanDerWaalsContact O-N 3.07Å; G92-Y96 PolarHBondContact O-N 3.34Å
93	D	84	Confident	84.8	Confident	1 Å²	1	32.9 Å²	32.9	1%	0.005	17%	0.167	C	C	.	.	H	α-helix	trans	-51.2	-40.1	-174.6	-50	34.9	0	0	0	113.2	Y80 Y96 V97 R109 N233	Y80-D93 HydrophobicContact CE1-CB 4.41Å; Y80-D93 WeakPolarHBondContact CE1-OD1 3.4Å; Y80-D93 PolarHBondContact OH-OD2 3.33Å; D93-Y96 PolarHBondContact O-N 3.22Å; D93-V97 WeakPolarHBondContact O-CG2 3.37Å; D93-V97 PolarHBondContact O-N 3.47Å; D93-R109 IonicContact OD2-CZ 2.74Å; D93-R109 IonicContact OD2-NE 2.85Å; D93-R109 IonicContact OD2-NH2 3.25Å; D93-R109 PolarHBondContact OD2-NH2 3.15Å; D93-N233 PolarHBondContact OD1-ND2 2.93Å; D93-N233 PolarHBondContact OD2-ND2 3.04Å
94	Y	85.7	Confident	84.8	Confident	14 Å²	14	35.9 Å²	35.9	6%	0.055	18%	0.18	C	C	.	.	H	α-helix	trans	-59.7	-49.1	179.8	161	-113.9	0	0	0	111.5	G92 Y96 V97 Y98 G106 L110 V331 Q333	G92-Y94 PolarHBondContact O-N 3.32Å; G92-Y94 VanDerWaalsContact O-N 3.11Å; Y94-Y96 VanDerWaalsContact C-N 3.29Å; Y94-Y96 PolarHBondContact O-N 3.26Å; Y94-V97 PolarHBondContact O-N 3.48Å; Y94-Y98 HydrophobicContact CE2-CD2 4.16Å; Y94-Y98 WeakPolarHBondContact O-CB 3.31Å; Y94-Y98 PolarHBondContact O-N 3.23Å; Y94-Y98 WeakPolarHBondContact OH-CD2 3.49Å; Y94-G106 WeakPolarHBondContact CD2-O 3.5Å; Y94-G106 WeakPolarHBondContact CE2-O 3.2Å; Y94-L110 HydrophobicContact CD2-CB 3.84Å; Y94-L110 HydrophobicContact CE2-CB 4.31Å; Y94-L110 HydrophobicContact CG-CB 4.46Å; Y94-V331 HydrophobicContact CE1-CG2 4.25Å; Y94-Q333 WeakPolarHBondContact OH-CG 3.29Å; Y94-Q333 PolarHBondContact OH-OE1 2.64Å; Y94-Q333 VanDerWaalsContact OH-OE1 3.09Å
95	I	85.1	Confident	85.1	Confident	8 Å²	8	40.9 Å²	40.9	4%	0.041	20%	0.202	C	C	.	.	H	α-helix	trans	-70	-30.5	-175.4	-160.1	64	0	0	0	111.4	I87 R89 G92 Y98 E99	I87-I95 HydrophobicContact CG2-CG1 4.49Å; I87-I95 HydrophobicContact CG2-CG2 4.19Å; R89-I95 HydrophobicContact CB-CG1 4.11Å; R89-I95 HydrophobicContact CB-CG2 4.46Å; G92-I95 VanDerWaalsContact O-CG2 3.26Å; G92-I95 WeakPolarHBondContact O-CG2 3.17Å; G92-I95 PolarHBondContact O-N 2.99Å; G92-I95 VanDerWaalsContact O-N 3.07Å; I95-Y98 HydrophobicContact CD1-CD1 4.36Å; I95-Y98 PolarHBondContact O-N 3.4Å; I95-E99 VanDerWaalsContact O-CB 3.27Å; I95-E99 WeakPolarHBondContact O-CB 3.26Å; I95-E99 PolarHBondContact O-N 3.43Å
96	Y	90	Very high	85.2	Confident	1 Å²	1	40.8 Å²	40.8	0%	0.004	20%	0.201	C	C	.	.	H	α-helix	trans	-64.1	-48.7	175.7	-52.7	-27.2	0	0	0	111.1	Y80 L83 G84 I87 G92 D93 Y94 E99 A100	Y80-Y96 HydrophobicContact CD1-CE2 4.04Å; Y80-Y96 HydrophobicContact CE1-CD2 4.49Å; Y80-Y96 HydrophobicContact CE1-CE2 4.27Å; L83-Y96 HydrophobicContact CB-CD1 4.25Å; L83-Y96 HydrophobicContact CB-CD2 3.9Å; L83-Y96 HydrophobicContact CB-CE1 4.25Å; L83-Y96 HydrophobicContact CB-CE2 3.89Å; L83-Y96 HydrophobicContact CB-CG 4.11Å; L83-Y96 HydrophobicContact CD1-CD2 3.95Å; L83-Y96 HydrophobicContact CD1-CG 4.33Å; G84-Y96 WeakPolarHBondContact CA-OH 3.25Å; G84-Y96 PolarHBondContact N-OH 2.91Å; I87-Y96 HydrophobicContact CB-CD1 4.15Å; I87-Y96 HydrophobicContact CB-CE1 4.13Å; I87-Y96 HydrophobicContact CD1-CD1 3.84Å; I87-Y96 HydrophobicContact CG2-CD1 4.45Å; G92-Y96 PolarHBondContact O-N 3.34Å; D93-Y96 PolarHBondContact O-N 3.22Å; Y94-Y96 VanDerWaalsContact C-N 3.29Å; Y94-Y96 PolarHBondContact O-N 3.26Å; Y96-E99 PolarHBondContact O-N 3.41Å; Y96-A100 VanDerWaalsContact O-CB 3.31Å; Y96-A100 WeakPolarHBondContact O-CB 3.39Å; Y96-A100 PolarHBondContact O-N 2.93Å
97	V	93	Very high	85.2	Confident	4 Å²	4	40.6 Å²	40.6	2%	0.024	20%	0.2	C	C	.	.	H	α-helix	trans	-65.6	-41.1	178.6	179.5	0	0	0	0	110.8	D93 Y94 E99 A100 F101 F105 R109 C386 I389	D93-V97 WeakPolarHBondContact O-CG2 3.37Å; D93-V97 PolarHBondContact O-N 3.47Å; Y94-V97 PolarHBondContact O-N 3.48Å; V97-E99 PolarHBondContact O-N 3.28Å; V97-A100 PolarHBondContact O-N 2.97Å; V97-F101 HydrophobicContact CG1-CD2 4.13Å; V97-F101 PolarHBondContact O-N 3.36Å; V97-F105 VanDerWaalsContact CG1-C 3.42Å; V97-F105 HydrophobicContact CG1-CB 3.72Å; V97-F105 WeakPolarHBondContact CG1-O 3.47Å; V97-R109 HydrophobicContact CB-CB 4.14Å; V97-R109 HydrophobicContact CB-CG 4.33Å; V97-R109 HydrophobicContact CG1-CB 4.12Å; V97-R109 HydrophobicContact CG2-CB 4.09Å; V97-R109 HydrophobicContact CG2-CG 3.89Å; V97-C386 WeakPolarHBondContact CG2-SG 3.47Å; V97-I389 HydrophobicContact CG2-CD1 4.03Å
98	Y	90.2	Very high	85.6	Confident	60 Å²	60	40.9 Å²	40.9	24%	0.235	20%	0.202	C	C	.	.	H	α-helix	trans	-58.7	-46.1	176	-175.7	-79.6	0	0	0	111.8	Y94 I95 G102 P103 V331	Y94-Y98 HydrophobicContact CE2-CD2 4.16Å; Y94-Y98 WeakPolarHBondContact O-CB 3.31Å; Y94-Y98 PolarHBondContact O-N 3.23Å; Y94-Y98 WeakPolarHBondContact OH-CD2 3.49Å; I95-Y98 HydrophobicContact CD1-CD1 4.36Å; I95-Y98 PolarHBondContact O-N 3.4Å; Y98-G102 CarbonylContact O-C 3.58Å; Y98-G102 WeakPolarHBondContact O-CA 3.43Å; Y98-G102 PolarHBondContact O-N 3.07Å; Y98-P103 HydrophobicContact CD2-CB 4.4Å; Y98-P103 HydrophobicContact CE2-CB 3.73Å; Y98-P103 HydrophobicContact CE2-CG 3.91Å; Y98-V331 HydrophobicContact CE2-CG1 3.79Å
99	E	89.2	Confident	86.6	Confident	80 Å²	80	36.3 Å²	36.3	37%	0.374	18%	0.18	S	C	.	.	H	α-helix	trans	-71.9	-32.4	-179	-176.3	63.9	-159.7	0	0	112.7	I87 I95 Y96 V97 F393 K397	I87-E99 HydrophobicContact CD1-CB 4.04Å; I87-E99 HydrophobicContact CD1-CG 3.93Å; I95-E99 VanDerWaalsContact O-CB 3.27Å; I95-E99 WeakPolarHBondContact O-CB 3.26Å; I95-E99 PolarHBondContact O-N 3.43Å; Y96-E99 PolarHBondContact O-N 3.41Å; V97-E99 PolarHBondContact O-N 3.28Å; E99-F393 HydrophobicContact CG-CZ 4.34Å; E99-K397 IonicContact OE1-NZ 2.94Å; E99-K397 PolarHBondContact OE1-NZ 3.33Å
100	A	92.9	Very high	87.5	Confident	26 Å²	26	29.4 Å²	29.4	22%	0.215	15%	0.154	C	C	.	.	H	α-helix	trans	-83.6	-41.9	-177.3	0	0	0	0	0	113.7	Y96 V97 I389 F393	Y96-A100 VanDerWaalsContact O-CB 3.31Å; Y96-A100 WeakPolarHBondContact O-CB 3.39Å; Y96-A100 PolarHBondContact O-N 2.93Å; V97-A100 PolarHBondContact O-N 2.97Å; A100-I389 HydrophobicContact CB-CB 4.3Å; A100-I389 HydrophobicContact CB-CD1 3.77Å; A100-I389 HydrophobicContact CB-CG1 3.74Å; A100-I389 HydrophobicContact CB-CG2 3.61Å; A100-F393 HydrophobicContact CB-CE1 3.67Å; A100-F393 HydrophobicContact CB-CZ 3.73Å
101	F	94.2	Very high	88.9	Confident	75 Å²	75	29.1 Å²	29.1	33%	0.329	15%	0.147	S	C	.	.	H	α-helix	trans	-122.1	-2.3	-170.2	-56.2	-57.3	0	0	0	113.2	V97 F105 V385 I389 V392	V97-F101 HydrophobicContact CG1-CD2 4.13Å; V97-F101 PolarHBondContact O-N 3.36Å; F101-F105 HydrophobicContact CB-CB 3.7Å; F101-F105 HydrophobicContact CB-CD2 3.61Å; F101-F105 HydrophobicContact CB-CE2 4.46Å; F101-F105 HydrophobicContact CB-CG 3.84Å; F101-F105 WeakPolarHBondContact O-CD2 3.46Å; F101-V385 HydrophobicContact CD2-CG1 4.44Å; F101-V385 HydrophobicContact CE2-CG1 3.9Å; F101-I389 HydrophobicContact CD2-CG1 4.43Å; F101-I389 HydrophobicContact CE2-CD1 4.1Å; F101-I389 HydrophobicContact CE2-CG1 3.62Å; F101-I389 HydrophobicContact CZ-CG1 4.06Å; F101-V392 HydrophobicContact CE1-CG2 4.34Å; F101-V392 HydrophobicContact CZ-CG2 4.29Å
102	G	91.4	Very high	90	Very high	21 Å²	21	28.9 Å²	28.9	22%	0.216	14%	0.144	C	C	.	.			trans	90.9	-177.8	175.3	0	0	0	0	0	114.7	Y98 F104 F105 G106	Y98-G102 CarbonylContact O-C 3.58Å; Y98-G102 WeakPolarHBondContact O-CA 3.43Å; Y98-G102 PolarHBondContact O-N 3.07Å; G102-F104 VanDerWaalsContact C-N 3.34Å; G102-F104 PolarHBondContact O-N 3.44Å; G102-F105 PolarHBondContact O-N 3.33Å; G102-G106 PolarHBondContact O-N 2.62Å; G102-G106 VanDerWaalsContact O-N 3.08Å
103	P	90.9	Very high	90.6	Very high	57 Å²	57	29.2 Å²	29.2	37%	0.37	15%	0.145	S	C	.	.	H	α-helix	trans	-61.3	-36.2	-168.3	-24.9	33.5	0	0	0	114.7	Y98 G106 F107 Q333	Y98-P103 HydrophobicContact CD2-CB 4.4Å; Y98-P103 HydrophobicContact CE2-CB 3.73Å; Y98-P103 HydrophobicContact CE2-CG 3.91Å; P103-G106 PolarHBondContact O-N 3.48Å; P103-F107 WeakPolarHBondContact O-CB 3.45Å; P103-F107 PolarHBondContact O-N 3.1Å; P103-Q333 PolarHBondContact O-NE2 3.49Å
104	F	93.4	Very high	90.8	Very high	64 Å²	64	29.2 Å²	29.2	28%	0.281	15%	0.145	S	C	.	.	H	α-helix	trans	-63.9	-51.4	-178.3	173.4	-110.3	0	0	0	112.2	G102 G106 F107 L108 I444 Y447	G102-F104 VanDerWaalsContact C-N 3.34Å; G102-F104 PolarHBondContact O-N 3.44Å; F104-G106 VanDerWaalsContact C-N 3.34Å; F104-F107 WeakPolarHBondContact O-CB 3.19Å; F104-F107 PolarHBondContact O-N 3.48Å; F104-L108 HydrophobicContact CD1-CD1 4.3Å; F104-L108 HydrophobicContact CE1-CD1 3.64Å; F104-L108 HydrophobicContact CE2-CD1 4.19Å; F104-L108 HydrophobicContact CE2-CG 4.35Å; F104-L108 HydrophobicContact CZ-CD1 3.6Å; F104-L108 HydrophobicContact CZ-CG 4.24Å; F104-L108 PolarHBondContact O-N 3.01Å; F104-I444 HydrophobicContact CE2-CG1 4.27Å; F104-I444 HydrophobicContact CE2-CG2 4.3Å; F104-I444 HydrophobicContact CZ-CD1 4.47Å; F104-I444 HydrophobicContact CZ-CG1 4.02Å; F104-I444 HydrophobicContact CZ-CG2 4.46Å; F104-Y447 HydrophobicContact CB-CE1 4.11Å; F104-Y447 AromaticContact CD2-CD1 3.51Å; F104-Y447 HydrophobicContact CD2-CD1 3.51Å; F104-Y447 AromaticContact CD2-CE1 3.67Å; F104-Y447 HydrophobicContact CD2-CE1 3.67Å; F104-Y447 AromaticContact CD2-CG 3.94Å; F104-Y447 HydrophobicContact CD2-CG 3.94Å; F104-Y447 HydrophobicContact CE2-CD1 4.12Å; F104-Y447 HydrophobicContact CE2-CG 4.5Å; F104-Y447 HydrophobicContact CG-CE1 4.37Å
105	F	93.4	Very high	91	Very high	105 Å²	105	29.5 Å²	29.5	46%	0.461	15%	0.149	S	C	.	.	H	α-helix	trans	-69.8	-34.8	179	-70.2	-75.8	0	0	0	111.7	V97 F101 G102 F107 L108 R109	V97-F105 VanDerWaalsContact CG1-C 3.42Å; V97-F105 HydrophobicContact CG1-CB 3.72Å; V97-F105 WeakPolarHBondContact CG1-O 3.47Å; F101-F105 HydrophobicContact CB-CB 3.7Å; F101-F105 HydrophobicContact CB-CD2 3.61Å; F101-F105 HydrophobicContact CB-CE2 4.46Å; F101-F105 HydrophobicContact CB-CG 3.84Å; F101-F105 WeakPolarHBondContact O-CD2 3.46Å; G102-F105 PolarHBondContact O-N 3.33Å; F105-F107 VanDerWaalsContact C-N 3.31Å; F105-F107 PolarHBondContact O-N 3.42Å; F105-L108 PolarHBondContact O-N 3.35Å; F105-R109 PolarHBondContact O-N 2.92Å
106	G	91.3	Very high	91.2	Very high	0 Å²	0	29.1 Å²	29.1	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-54.3	-49.2	168.9	0	0	0	0	0	111.2	Y94 G102 P103 F104 L108 R109 L110	Y94-G106 WeakPolarHBondContact CD2-O 3.5Å; Y94-G106 WeakPolarHBondContact CE2-O 3.2Å; G102-G106 PolarHBondContact O-N 2.62Å; G102-G106 VanDerWaalsContact O-N 3.08Å; P103-G106 PolarHBondContact O-N 3.48Å; F104-G106 VanDerWaalsContact C-N 3.34Å; G106-L108 PolarHBondContact O-N 3.29Å; G106-R109 PolarHBondContact O-N 3.03Å; G106-L110 PolarHBondContact O-N 2.77Å
107	F	91.5	Very high	91.2	Very high	5 Å²	5	29.2 Å²	29.2	2%	0.022	15%	0.148	C	C	.	.	H	α-helix	trans	-62	-44.2	178.3	-179.4	-87.8	0	0	0	112.1	P103 F104 F105 R109 L110 W111 Q333 G443 V446 Y447	P103-F107 WeakPolarHBondContact O-CB 3.45Å; P103-F107 PolarHBondContact O-N 3.1Å; F104-F107 WeakPolarHBondContact O-CB 3.19Å; F104-F107 PolarHBondContact O-N 3.48Å; F105-F107 VanDerWaalsContact C-N 3.31Å; F105-F107 PolarHBondContact O-N 3.42Å; F107-R109 VanDerWaalsContact C-N 3.31Å; F107-R109 PolarHBondContact O-N 3.26Å; F107-L110 PolarHBondContact O-N 3.01Å; F107-W111 HydrophobicContact CD1-CB 4.33Å; F107-W111 HydrophobicContact CE1-CB 4.01Å; F107-W111 HydrophobicContact CE1-CD2 4.34Å; F107-W111 HydrophobicContact CE1-CE3 4.12Å; F107-W111 HydrophobicContact CE1-CG 4.32Å; F107-W111 AromaticContact CZ-CE3 3.85Å; F107-W111 HydrophobicContact CZ-CE3 3.85Å; F107-W111 VanDerWaalsContact O-CB 3.27Å; F107-W111 WeakPolarHBondContact O-CB 3.4Å; F107-W111 PolarHBondContact O-N 3.22Å; F107-Q333 HydrophobicContact CD2-CB 4.26Å; F107-Q333 VanDerWaalsContact CE2-O 3.28Å; F107-Q333 WeakPolarHBondContact CE2-O 3.43Å; F107-G443 WeakPolarHBondContact CE1-O 3.38Å; F107-V446 HydrophobicContact CE1-CB 4.48Å; F107-V446 HydrophobicContact CZ-CB 4.31Å; F107-V446 HydrophobicContact CZ-CG1 3.87Å; F107-Y447 HydrophobicContact CB-CD2 3.49Å; F107-Y447 VanDerWaalsContact CB-CD2 3.49Å; F107-Y447 HydrophobicContact CB-CE2 3.94Å; F107-Y447 HydrophobicContact CB-CG 4.45Å; F107-Y447 AromaticContact CD1-CD2 3.88Å; F107-Y447 HydrophobicContact CD1-CD2 3.88Å; F107-Y447 HydrophobicContact CD1-CG 4.18Å; F107-Y447 HydrophobicContact CD2-CD2 4.04Å; F107-Y447 AromaticContact CG-CD2 3.51Å; F107-Y447 HydrophobicContact CG-CD2 3.51Å; F107-Y447 HydrophobicContact CG-CE2 4.39Å; F107-Y447 HydrophobicContact CG-CG 4.28Å
108	L	93.1	Very high	91.1	Very high	24 Å²	24	29.2 Å²	29.2	13%	0.126	15%	0.147	C	C	.	.	H	α-helix	trans	-61.7	-39	178.1	-71.1	-179	0	0	0	112.3	F104 F105 G106 W111 S112 I444	F104-L108 HydrophobicContact CD1-CD1 4.3Å; F104-L108 HydrophobicContact CE1-CD1 3.64Å; F104-L108 HydrophobicContact CE2-CD1 4.19Å; F104-L108 HydrophobicContact CE2-CG 4.35Å; F104-L108 HydrophobicContact CZ-CD1 3.6Å; F104-L108 HydrophobicContact CZ-CG 4.24Å; F104-L108 PolarHBondContact O-N 3.01Å; F105-L108 PolarHBondContact O-N 3.35Å; G106-L108 PolarHBondContact O-N 3.29Å; L108-W111 PolarHBondContact O-N 3.13Å; L108-S112 WeakPolarHBondContact O-CB 3.27Å; L108-S112 PolarHBondContact O-N 3.44Å; L108-S112 PolarHBondContact O-OG 3.28Å; L108-I444 HydrophobicContact CD2-CG1 3.99Å
109	R	91.9	Very high	91.2	Very high	15 Å²	15	26.4 Å²	26.4	6%	0.057	14%	0.136	C	C	.	.	H	α-helix	trans	-63.7	-42.4	174.7	175.2	66.1	-168.3	93.8	-4.1	111.8	D93 V97 F105 G106 F107 S112 E113	D93-R109 IonicContact OD2-CZ 2.74Å; D93-R109 IonicContact OD2-NE 2.85Å; D93-R109 IonicContact OD2-NH2 3.25Å; D93-R109 PolarHBondContact OD2-NH2 3.15Å; V97-R109 HydrophobicContact CB-CB 4.14Å; V97-R109 HydrophobicContact CB-CG 4.33Å; V97-R109 HydrophobicContact CG1-CB 4.12Å; V97-R109 HydrophobicContact CG2-CB 4.09Å; V97-R109 HydrophobicContact CG2-CG 3.89Å; F105-R109 PolarHBondContact O-N 2.92Å; G106-R109 PolarHBondContact O-N 3.03Å; F107-R109 VanDerWaalsContact C-N 3.31Å; F107-R109 PolarHBondContact O-N 3.26Å; R109-S112 PolarHBondContact O-OG 3.24Å; R109-S112 VanDerWaalsContact O-OG 3.04Å; R109-E113 IonicContact CZ-OE2 3.24Å; R109-E113 VanDerWaalsContact CZ-OE2 3.25Å; R109-E113 IonicContact NH1-OE2 2.82Å; R109-E113 PolarHBondContact NH1-OE2 3.33Å; R109-E113 IonicContact NH2-OE2 3.45Å; R109-E113 PolarHBondContact NH2-OE2 3.25Å; R109-E113 PolarHBondContact O-N 2.85Å
110	L	89.6	Confident	91.4	Very high	5 Å²	5	22.6 Å²	22.6	3%	0.026	12%	0.118	C	C	.	.	H	α-helix	trans	-65.6	-45.7	176	176.9	70.3	0	0	0	110.9	Y94 G106 F107 E113 V114 A328 M334	Y94-L110 HydrophobicContact CD2-CB 3.84Å; Y94-L110 HydrophobicContact CE2-CB 4.31Å; Y94-L110 HydrophobicContact CG-CB 4.46Å; G106-L110 PolarHBondContact O-N 2.77Å; F107-L110 PolarHBondContact O-N 3.01Å; L110-E113 WeakPolarHBondContact O-CB 3.43Å; L110-E113 PolarHBondContact O-N 3.45Å; L110-E113 VanDerWaalsContact O-N 3.15Å; L110-V114 HydrophobicContact CD1-CG1 3.92Å; L110-V114 HydrophobicContact CG-CG1 4.5Å; L110-V114 WeakPolarHBondContact O-CG2 3.2Å; L110-V114 PolarHBondContact O-N 3.24Å; L110-A328 HydrophobicContact CD1-CB 3.89Å; L110-A328 HydrophobicContact CD2-CB 3.3Å; L110-A328 HydrophobicContact CG-CB 4.23Å; L110-M334 HydrophobicContact CD2-CE 3.6Å; L110-M334 HydrophobicContact CD2-CG 3.69Å; L110-M334 HydrophobicContact CG-CE 3.9Å
111	W	91.3	Very high	91.4	Very high	36 Å²	36	21.9 Å²	21.9	14%	0.136	11%	0.112	C	C	.	.	H	α-helix	trans	-58.5	-49.4	179.5	-178.9	-97.3	0	0	0	111.3	F107 L108 E113 V114 V115 I439 T442 G443 V446	F107-W111 HydrophobicContact CD1-CB 4.33Å; F107-W111 HydrophobicContact CE1-CB 4.01Å; F107-W111 HydrophobicContact CE1-CD2 4.34Å; F107-W111 HydrophobicContact CE1-CE3 4.12Å; F107-W111 HydrophobicContact CE1-CG 4.32Å; F107-W111 AromaticContact CZ-CE3 3.85Å; F107-W111 HydrophobicContact CZ-CE3 3.85Å; F107-W111 VanDerWaalsContact O-CB 3.27Å; F107-W111 WeakPolarHBondContact O-CB 3.4Å; F107-W111 PolarHBondContact O-N 3.22Å; L108-W111 PolarHBondContact O-N 3.13Å; W111-E113 VanDerWaalsContact C-N 3.25Å; W111-E113 PolarHBondContact O-N 2.88Å; W111-V114 PolarHBondContact O-N 2.8Å; W111-V115 HydrophobicContact CD2-CB 4.39Å; W111-V115 HydrophobicContact CD2-CG2 3.69Å; W111-V115 HydrophobicContact CE3-CG2 3.69Å; W111-V115 HydrophobicContact CG-CG2 4.37Å; W111-V115 HydrophobicContact CH2-CG2 3.84Å; W111-V115 HydrophobicContact CZ2-CB 4.38Å; W111-V115 HydrophobicContact CZ2-CG1 4.09Å; W111-V115 HydrophobicContact CZ2-CG2 3.85Å; W111-V115 HydrophobicContact CZ3-CG2 3.76Å; W111-V115 VanDerWaalsContact O-CB 3.26Å; W111-V115 WeakPolarHBondContact O-CB 3.4Å; W111-V115 WeakPolarHBondContact O-CG2 3.31Å; W111-V115 PolarHBondContact O-N 3.34Å; W111-I439 PolarHBondContact NE1-O 3.46Å; W111-I439 VanDerWaalsContact NE1-O 3.14Å; W111-T442 PolarHBondContact NE1-OG1 3.47Å; W111-G443 VanDerWaalsContact CD1-CA 3.43Å; W111-V446 HydrophobicContact CE3-CG1 4.34Å; W111-V446 HydrophobicContact CH2-CB 4.3Å; W111-V446 HydrophobicContact CH2-CG1 4.2Å; W111-V446 HydrophobicContact CH2-CG2 3.79Å; W111-V446 HydrophobicContact CZ2-CG2 4.16Å; W111-V446 HydrophobicContact CZ3-CB 4.23Å; W111-V446 HydrophobicContact CZ3-CG1 3.78Å; W111-V446 HydrophobicContact CZ3-CG2 4.21Å
112	S	91.5	Very high	91.3	Very high	6 Å²	6	18.3 Å²	18.3	4%	0.042	10%	0.096	C	C	.	.	I	π-helix	trans	-62.2	-33.7	176.8	68.9	0	0	0	0	112.1	L108 R109 V116 A117	L108-S112 WeakPolarHBondContact O-CB 3.27Å; L108-S112 PolarHBondContact O-N 3.44Å; L108-S112 PolarHBondContact O-OG 3.28Å; R109-S112 PolarHBondContact O-OG 3.24Å; R109-S112 VanDerWaalsContact O-OG 3.04Å; S112-V116 WeakPolarHBondContact O-CA 3.49Å; S112-V116 WeakPolarHBondContact O-CB 3.49Å; S112-V116 PolarHBondContact O-N 3Å; S112-A117 PolarHBondContact O-N 3.32Å
113	E	89.3	Confident	91.4	Very high	7 Å²	7	17.3 Å²	17.3	3%	0.033	9%	0.086	C	C	.	.	I	π-helix	trans	-68.4	-54.8	176.5	-164.2	68.8	-173.1	0	0	112	R109 L110 W111 A117 R118 M324	R109-E113 IonicContact CZ-OE2 3.24Å; R109-E113 VanDerWaalsContact CZ-OE2 3.25Å; R109-E113 IonicContact NH1-OE2 2.82Å; R109-E113 PolarHBondContact NH1-OE2 3.33Å; R109-E113 IonicContact NH2-OE2 3.45Å; R109-E113 PolarHBondContact NH2-OE2 3.25Å; R109-E113 PolarHBondContact O-N 2.85Å; L110-E113 WeakPolarHBondContact O-CB 3.43Å; L110-E113 PolarHBondContact O-N 3.45Å; L110-E113 VanDerWaalsContact O-N 3.15Å; W111-E113 VanDerWaalsContact C-N 3.25Å; W111-E113 PolarHBondContact O-N 2.88Å; E113-A117 PolarHBondContact O-N 2.96Å; E113-R118 HydrophobicContact CG-CG 4.11Å; E113-R118 WeakPolarHBondContact O-CG 3.44Å; E113-R118 PolarHBondContact O-N 3Å; E113-R118 IonicContact OE1-CZ 2.6Å; E113-R118 VanDerWaalsContact OE1-CZ 3.3Å; E113-R118 IonicContact OE1-NE 3.5Å; E113-R118 PolarHBondContact OE1-NE 3.35Å; E113-R118 IonicContact OE1-NH2 3.62Å; E113-R118 PolarHBondContact OE1-NH2 3.36Å; E113-M324 HydrophobicContact CG-CE 3.99Å; E113-M324 HydrophobicContact CG-SD 3.54Å; E113-M324 VanDerWaalsContact CG-SD 3.54Å
114	V	88.5	Confident	91.5	Very high	0 Å²	0	14.6 Å²	14.6	0%	0	7%	0.068	C	C	.	.	I	π-helix	trans	-84.3	-22.5	-167.3	-55.2	0	0	0	0	113.7	L110 W111 P119 F325 M334	L110-V114 HydrophobicContact CD1-CG1 3.92Å; L110-V114 HydrophobicContact CG-CG1 4.5Å; L110-V114 WeakPolarHBondContact O-CG2 3.2Å; L110-V114 PolarHBondContact O-N 3.24Å; W111-V114 PolarHBondContact O-N 2.8Å; V114-P119 WeakPolarHBondContact O-CD 3.32Å; V114-P119 WeakPolarHBondContact O-CG 3.45Å; V114-F325 HydrophobicContact CB-CE1 4.02Å; V114-F325 HydrophobicContact CB-CE2 4.22Å; V114-F325 HydrophobicContact CB-CZ 3.59Å; V114-F325 HydrophobicContact CG1-CE1 4.2Å; V114-F325 HydrophobicContact CG1-CE2 4.34Å; V114-F325 HydrophobicContact CG1-CZ 4Å; V114-F325 HydrophobicContact CG2-CE1 3.92Å; V114-F325 HydrophobicContact CG2-CZ 3.9Å; V114-M334 HydrophobicContact CG2-CE 3.71Å
115	V	89.7	Confident	91.4	Very high	21 Å²	21	12.1 Å²	12.1	13%	0.127	6%	0.058	C	C	.	.	I	π-helix	trans	-99.3	-26.1	178.1	-177	0	0	0	0	111.6	W111 F354 Y362	W111-V115 HydrophobicContact CD2-CB 4.39Å; W111-V115 HydrophobicContact CD2-CG2 3.69Å; W111-V115 HydrophobicContact CE3-CG2 3.69Å; W111-V115 HydrophobicContact CG-CG2 4.37Å; W111-V115 HydrophobicContact CH2-CG2 3.84Å; W111-V115 HydrophobicContact CZ2-CB 4.38Å; W111-V115 HydrophobicContact CZ2-CG1 4.09Å; W111-V115 HydrophobicContact CZ2-CG2 3.85Å; W111-V115 HydrophobicContact CZ3-CG2 3.76Å; W111-V115 VanDerWaalsContact O-CB 3.26Å; W111-V115 WeakPolarHBondContact O-CB 3.4Å; W111-V115 WeakPolarHBondContact O-CG2 3.31Å; W111-V115 PolarHBondContact O-N 3.34Å; V115-F354 HydrophobicContact CG2-CZ 4.34Å; V115-Y362 VanDerWaalsContact O-CE2 3.23Å; V115-Y362 WeakPolarHBondContact O-CE2 3.4Å; V115-Y362 PolarHBondContact O-OH 2.94Å; V115-Y362 VanDerWaalsContact O-OH 3.08Å
116	V	89.9	Confident	91.5	Very high	0 Å²	0	7.1 Å²	7.1	0%	0	4%	0.036	C	C	.	.	I	π-helix	trans	-114.4	-68	-177.2	-177.1	0	0	0	0	112.2	S112 R118 P119 A120 Y362 Y374 V378 I439	S112-V116 WeakPolarHBondContact O-CA 3.49Å; S112-V116 WeakPolarHBondContact O-CB 3.49Å; S112-V116 PolarHBondContact O-N 3Å; V116-R118 PolarHBondContact O-N 2.9Å; V116-P119 WeakPolarHBondContact O-CD 3.37Å; V116-A120 WeakPolarHBondContact O-CB 3.08Å; V116-A120 PolarHBondContact O-N 2.96Å; V116-Y362 WeakPolarHBondContact CA-OH 3.37Å; V116-Y374 HydrophobicContact CG1-CD1 4.37Å; V116-Y374 HydrophobicContact CG1-CE1 3.35Å; V116-Y374 HydrophobicContact CG1-CE2 4.46Å; V116-Y374 WeakPolarHBondContact CG1-OH 3.35Å; V116-Y374 WeakPolarHBondContact CG2-OH 3.5Å; V116-V378 HydrophobicContact CB-CG1 4.1Å; V116-V378 HydrophobicContact CG1-CB 4.06Å; V116-V378 HydrophobicContact CG1-CG1 3.86Å; V116-V378 HydrophobicContact CG1-CG2 4.07Å; V116-I439 HydrophobicContact CG2-CB 4.23Å; V116-I439 HydrophobicContact CG2-CG2 3.31Å
117	A	89.9	Confident	91.5	Very high	3 Å²	3	7.5 Å²	7.5	3%	0.025	4%	0.038	C	C	.	.	I	π-helix	trans	-64	-48.4	-163.4	0	0	0	0	0	112.4	S112 E113 S121 L375	S112-A117 PolarHBondContact O-N 3.32Å; E113-A117 PolarHBondContact O-N 2.96Å; A117-S121 VanDerWaalsContact O-CB 3.26Å; A117-S121 WeakPolarHBondContact O-CB 3.43Å; A117-S121 PolarHBondContact O-N 3.28Å; A117-S121 PolarHBondContact O-OG 3.42Å; A117-L375 VanDerWaalsContact CA-CD1 3.42Å; A117-L375 HydrophobicContact CB-CD1 3.89Å; A117-L375 WeakPolarHBondContact O-CD1 3.5Å
118	R	90	Very high	91.5	Very high	4 Å²	4	7.4 Å²	7.4	2%	0.015	4%	0.037	C	C	.	.	H	α-helix	trans	-69	-50.4	-178.7	-57.2	-68	176.9	141.9	-5.7	112.4	E113 V116 A120 S121 V122 Y234 T317 T320 T321	E113-R118 HydrophobicContact CG-CG 4.11Å; E113-R118 WeakPolarHBondContact O-CG 3.44Å; E113-R118 PolarHBondContact O-N 3Å; E113-R118 IonicContact OE1-CZ 2.6Å; E113-R118 VanDerWaalsContact OE1-CZ 3.3Å; E113-R118 IonicContact OE1-NE 3.5Å; E113-R118 PolarHBondContact OE1-NE 3.35Å; E113-R118 IonicContact OE1-NH2 3.62Å; E113-R118 PolarHBondContact OE1-NH2 3.36Å; V116-R118 PolarHBondContact O-N 2.9Å; R118-A120 PolarHBondContact O-N 3.49Å; R118-S121 PolarHBondContact O-N 3.49Å; R118-V122 WeakPolarHBondContact O-CG2 3.19Å; R118-V122 PolarHBondContact O-N 2.87Å; R118-Y234 PolarHBondContact NH1-OH 2.98Å; R118-T317 HydrophobicContact CB-CG2 4.32Å; R118-T320 PolarHBondContact NH1-OG1 3Å; R118-T321 HydrophobicContact CB-CG2 4.04Å; R118-T321 WeakPolarHBondContact CB-OG1 3.46Å; R118-T321 WeakPolarHBondContact CD-OG1 3.49Å; R118-T321 HydrophobicContact CG-CG2 4.12Å; R118-T321 WeakPolarHBondContact CG-OG1 3.37Å
119	P	92.9	Very high	91.5	Very high	0 Å²	0	7.2 Å²	7.2	0%	0	4%	0.036	C	C	.	.	H	α-helix	trans	-65.8	-39.7	-178.9	-24.2	37.9	0	0	0	113.4	V114 V116 V122 A123 T358 S359 Y362	V114-P119 WeakPolarHBondContact O-CD 3.32Å; V114-P119 WeakPolarHBondContact O-CG 3.45Å; V116-P119 WeakPolarHBondContact O-CD 3.37Å; P119-V122 PolarHBondContact O-N 3.21Å; P119-A123 WeakPolarHBondContact O-CB 3.39Å; P119-A123 PolarHBondContact O-N 3.47Å; P119-T358 VanDerWaalsContact CG-OG1 3.25Å; P119-T358 WeakPolarHBondContact CG-OG1 3.32Å; P119-S359 WeakPolarHBondContact CA-OG 3.16Å; P119-Y362 HydrophobicContact CB-CD2 3.67Å; P119-Y362 HydrophobicContact CB-CE2 3.83Å
120	A	92.7	Very high	91.5	Very high	0 Å²	0	6.5 Å²	6.5	0%	0	3%	0.033	C	C	.	.	H	α-helix	trans	-64.8	-41.2	176.1	0	0	0	0	0	111.3	V116 R118 V122 A123 I124 Y362 L371 L375	V116-A120 WeakPolarHBondContact O-CB 3.08Å; V116-A120 PolarHBondContact O-N 2.96Å; R118-A120 PolarHBondContact O-N 3.49Å; A120-V122 PolarHBondContact O-N 3.32Å; A120-A123 PolarHBondContact O-N 2.97Å; A120-I124 WeakPolarHBondContact O-CD1 3.33Å; A120-I124 VanDerWaalsContact O-CG1 3.27Å; A120-I124 WeakPolarHBondContact O-CG1 3.31Å; A120-I124 PolarHBondContact O-N 3.37Å; A120-Y362 HydrophobicContact CB-CD1 4.18Å; A120-Y362 HydrophobicContact CB-CE1 4.25Å; A120-Y362 HydrophobicContact CB-CG 4.33Å; A120-L371 HydrophobicContact CB-CD2 4.26Å; A120-L375 HydrophobicContact CB-CD1 4.42Å
121	S	92.1	Very high	91.5	Very high	11 Å²	11	9.1 Å²	9.1	8%	0.077	4%	0.044	C	C	.	.	H	α-helix	trans	-59.8	-45.8	174.1	-62.4	0	0	0	0	111.7	A117 R118 A123 I124 M125 L375	A117-S121 VanDerWaalsContact O-CB 3.26Å; A117-S121 WeakPolarHBondContact O-CB 3.43Å; A117-S121 PolarHBondContact O-N 3.28Å; A117-S121 PolarHBondContact O-OG 3.42Å; R118-S121 PolarHBondContact O-N 3.49Å; S121-A123 VanDerWaalsContact C-N 3.33Å; S121-A123 PolarHBondContact O-N 3.33Å; S121-I124 PolarHBondContact O-N 3.48Å; S121-M125 WeakPolarHBondContact O-CB 3.45Å; S121-M125 VanDerWaalsContact O-CE 3.31Å; S121-M125 WeakPolarHBondContact O-CE 3.49Å; S121-M125 VanDerWaalsContact O-CG 3.22Å; S121-M125 WeakPolarHBondContact O-CG 3.14Å; S121-M125 PolarHBondContact O-N 3.27Å; S121-L375 WeakPolarHBondContact OG-CD2 3.45Å
122	V	92.9	Very high	91.5	Very high	0 Å²	0	7.5 Å²	7.5	0%	0	4%	0.038	C	C	.	.	H	α-helix	trans	-58.7	-46.1	175.6	167.4	0	0	0	0	110.8	R118 P119 A120 M125 S126 I156 V314 T317 V318 S359	R118-V122 WeakPolarHBondContact O-CG2 3.19Å; R118-V122 PolarHBondContact O-N 2.87Å; P119-V122 PolarHBondContact O-N 3.21Å; A120-V122 PolarHBondContact O-N 3.32Å; V122-M125 PolarHBondContact O-N 3.5Å; V122-S126 WeakPolarHBondContact O-CB 3.25Å; V122-S126 PolarHBondContact O-N 2.98Å; V122-S126 PolarHBondContact O-OG 3.03Å; V122-S126 VanDerWaalsContact O-OG 3.13Å; V122-I156 HydrophobicContact CG1-CD1 3.9Å; V122-I156 HydrophobicContact CG1-CG1 3.76Å; V122-I156 HydrophobicContact CG1-CG2 4.25Å; V122-V314 HydrophobicContact CG1-CG1 3.91Å; V122-T317 HydrophobicContact CG2-CG2 3.7Å; V122-V318 HydrophobicContact CG2-CG2 4.19Å; V122-S359 WeakPolarHBondContact CB-OG 3.42Å; V122-S359 WeakPolarHBondContact CG1-OG 3.43Å
123	A	94.5	Very high	91.4	Very high	0 Å²	0	10.4 Å²	10.4	0%	0	5%	0.052	C	C	.	.	H	α-helix	trans	-60.2	-49	178	0	0	0	0	0	112.2	P119 A120 S121 M125 S126 M127 L363	P119-A123 WeakPolarHBondContact O-CB 3.39Å; P119-A123 PolarHBondContact O-N 3.47Å; A120-A123 PolarHBondContact O-N 2.97Å; S121-A123 VanDerWaalsContact C-N 3.33Å; S121-A123 PolarHBondContact O-N 3.33Å; A123-M125 VanDerWaalsContact C-N 3.33Å; A123-M125 PolarHBondContact O-N 2.95Å; A123-S126 PolarHBondContact O-N 3.48Å; A123-M127 WeakPolarHBondContact O-CB 3.28Å; A123-M127 VanDerWaalsContact O-CG 3.32Å; A123-M127 WeakPolarHBondContact O-CG 3.41Å; A123-M127 PolarHBondContact O-N 3.3Å; A123-L363 HydrophobicContact CB-CD2 3.92Å; A123-L363 HydrophobicContact CB-CG 4.46Å
124	I	92.4	Very high	91.4	Very high	0 Å²	0	10.5 Å²	10.5	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-56.5	-48	177.1	-69.1	158	0	0	0	110.7	A120 S121 M127 T128 F227 I368 L371 I372 L375	A120-I124 WeakPolarHBondContact O-CD1 3.33Å; A120-I124 VanDerWaalsContact O-CG1 3.27Å; A120-I124 WeakPolarHBondContact O-CG1 3.31Å; A120-I124 PolarHBondContact O-N 3.37Å; S121-I124 PolarHBondContact O-N 3.48Å; I124-M127 PolarHBondContact O-N 3.08Å; I124-T128 WeakPolarHBondContact O-CB 3.08Å; I124-T128 PolarHBondContact O-N 3.48Å; I124-T128 PolarHBondContact O-OG1 3.38Å; I124-F227 HydrophobicContact CB-CZ 4.14Å; I124-F227 HydrophobicContact CD1-CE2 4.08Å; I124-F227 HydrophobicContact CD1-CZ 4.47Å; I124-F227 HydrophobicContact CG2-CE1 3.78Å; I124-F227 HydrophobicContact CG2-CE2 4.1Å; I124-F227 HydrophobicContact CG2-CZ 3.38Å; I124-I368 HydrophobicContact CG2-CG2 4Å; I124-L371 HydrophobicContact CD1-CB 4.02Å; I124-L371 HydrophobicContact CG1-CB 3.8Å; I124-I372 HydrophobicContact CD1-CG1 3.71Å; I124-I372 HydrophobicContact CG1-CG1 4.18Å; I124-I372 HydrophobicContact CG2-CD1 4.16Å; I124-I372 HydrophobicContact CG2-CG1 4.04Å; I124-L375 HydrophobicContact CD1-CB 4.48Å; I124-L375 HydrophobicContact CD1-CD2 3.7Å
125	M	91.9	Very high	91.3	Very high	13 Å²	13	11.9 Å²	11.9	6%	0.064	6%	0.061	C	C	.	.	H	α-helix	trans	-66.8	-41.4	-178.7	-68.2	-169.4	-76.2	0	0	112.6	S43 S121 V122 A123 T128 F129 F227 G313 V314 T317	S43-M125 VanDerWaalsContact OG-CG 3.23Å; S43-M125 WeakPolarHBondContact OG-CG 3.25Å; S121-M125 WeakPolarHBondContact O-CB 3.45Å; S121-M125 VanDerWaalsContact O-CE 3.31Å; S121-M125 WeakPolarHBondContact O-CE 3.49Å; S121-M125 VanDerWaalsContact O-CG 3.22Å; S121-M125 WeakPolarHBondContact O-CG 3.14Å; S121-M125 PolarHBondContact O-N 3.27Å; V122-M125 PolarHBondContact O-N 3.5Å; A123-M125 VanDerWaalsContact C-N 3.33Å; A123-M125 PolarHBondContact O-N 2.95Å; M125-T128 WeakPolarHBondContact O-CB 3.33Å; M125-T128 PolarHBondContact O-N 3.19Å; M125-F129 PolarHBondContact O-N 3.41Å; M125-F227 HydrophobicContact CG-CZ 4.48Å; M125-G313 WeakPolarHBondContact CE-O 3.43Å; M125-V314 HydrophobicContact CB-CG2 3.53Å; M125-T317 HydrophobicContact CE-CG2 4.45Å; M125-T317 WeakPolarHBondContact CE-OG1 3.31Å
126	S	94.4	Very high	91	Very high	0 Å²	0	13.2 Å²	13.2	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-68.8	-34.9	177	-67.4	0	0	0	0	112.7	V122 A123 F129 A130 A152 I156 V314	V122-S126 WeakPolarHBondContact O-CB 3.25Å; V122-S126 PolarHBondContact O-N 2.98Å; V122-S126 PolarHBondContact O-OG 3.03Å; V122-S126 VanDerWaalsContact O-OG 3.13Å; A123-S126 PolarHBondContact O-N 3.48Å; S126-F129 WeakPolarHBondContact O-CB 3.47Å; S126-F129 PolarHBondContact O-N 2.91Å; S126-A130 WeakPolarHBondContact O-CB 3.2Å; S126-A130 PolarHBondContact O-N 2.83Å; S126-A152 WeakPolarHBondContact O-CB 3.3Å; S126-I156 WeakPolarHBondContact OG-CG1 3.35Å; S126-V314 VanDerWaalsContact OG-CG2 3.23Å; S126-V314 WeakPolarHBondContact OG-CG2 3.36Å
127	M	92.5	Very high	91	Very high	8 Å²	8	18.9 Å²	18.9	4%	0.039	10%	0.099	C	C	.	.	H	α-helix	trans	-68.2	-38.1	171.6	-71.6	-169.9	-72.2	0	0	111.7	A123 I124 A130 K131 A152 L363 I368 L371	A123-M127 WeakPolarHBondContact O-CB 3.28Å; A123-M127 VanDerWaalsContact O-CG 3.32Å; A123-M127 WeakPolarHBondContact O-CG 3.41Å; A123-M127 PolarHBondContact O-N 3.3Å; I124-M127 PolarHBondContact O-N 3.08Å; M127-A130 PolarHBondContact O-N 2.95Å; M127-K131 WeakPolarHBondContact O-CG 3.41Å; M127-K131 PolarHBondContact O-N 2.77Å; M127-A152 HydrophobicContact CG-CB 4.08Å; M127-L363 HydrophobicContact CG-CD2 3.6Å; M127-L363 HydrophobicContact SD-CD2 4.24Å; M127-I368 HydrophobicContact CB-CD1 3.74Å; M127-I368 HydrophobicContact CB-CG1 3.9Å; M127-I368 HydrophobicContact CE-CG1 3.72Å; M127-I368 HydrophobicContact SD-CG1 3.99Å; M127-L371 HydrophobicContact CE-CD1 3.27Å
128	T	91	Very high	90.8	Very high	2 Å²	2	21.6 Å²	21.6	1%	0.012	11%	0.11	C	C	.	.	H	α-helix	trans	-61.6	-47.6	173.6	-52.6	0	0	0	0	110.6	V47 I124 M125 A130 K131 Y132 T310	V47-T128 HydrophobicContact CG2-CG2 3.32Å; V47-T128 WeakPolarHBondContact CG2-OG1 3.49Å; I124-T128 WeakPolarHBondContact O-CB 3.08Å; I124-T128 PolarHBondContact O-N 3.48Å; I124-T128 PolarHBondContact O-OG1 3.38Å; M125-T128 WeakPolarHBondContact O-CB 3.33Å; M125-T128 PolarHBondContact O-N 3.19Å; T128-A130 VanDerWaalsContact C-N 3.29Å; T128-A130 PolarHBondContact O-N 3.19Å; T128-K131 PolarHBondContact O-N 2.9Å; T128-Y132 HydrophobicContact CG2-CD2 3.82Å; T128-Y132 HydrophobicContact CG2-CE2 3.89Å; T128-Y132 VanDerWaalsContact O-CD2 3.31Å; T128-Y132 WeakPolarHBondContact O-CD2 3.17Å; T128-Y132 PolarHBondContact O-N 3.2Å; T128-T310 HydrophobicContact CG2-CG2 3.54Å
129	F	92.5	Very high	90.3	Very high	21 Å²	21	25.1 Å²	25.1	9%	0.092	13%	0.134	C	C	.	.	H	α-helix	trans	-50.7	-51	172.8	164.9	-96.8	0	0	0	111.6	M125 S126 K131 Y132 I133 L151 C155 A307 T310 F311	M125-F129 PolarHBondContact O-N 3.41Å; S126-F129 WeakPolarHBondContact O-CB 3.47Å; S126-F129 PolarHBondContact O-N 2.91Å; F129-K131 PolarHBondContact O-N 3.19Å; F129-Y132 PolarHBondContact O-N 3.38Å; F129-I133 HydrophobicContact CD2-CD1 4.11Å; F129-I133 HydrophobicContact CD2-CG1 4.42Å; F129-I133 HydrophobicContact CE1-CD1 4.07Å; F129-I133 HydrophobicContact CE2-CD1 3.28Å; F129-I133 HydrophobicContact CE2-CG1 4.04Å; F129-I133 HydrophobicContact CZ-CD1 3.27Å; F129-I133 HydrophobicContact CZ-CG1 4.25Å; F129-I133 PolarHBondContact O-N 3.43Å; F129-L151 HydrophobicContact CE1-CD1 4.41Å; F129-L151 HydrophobicContact CE1-CG 4.23Å; F129-C155 HydrophobicContact CD1-CB 3.63Å; F129-C155 HydrophobicContact CE1-CB 3.69Å; F129-C155 HydrophobicContact CG-CB 4.45Å; F129-A307 HydrophobicContact CD2-CB 3.96Å; F129-A307 WeakPolarHBondContact CD2-O 3.39Å; F129-A307 HydrophobicContact CE2-CB 4.11Å; F129-T310 VanDerWaalsContact CA-OG1 3.3Å; F129-T310 WeakPolarHBondContact CA-OG1 3.23Å; F129-T310 VanDerWaalsContact CB-OG1 3.29Å; F129-T310 WeakPolarHBondContact CB-OG1 3.43Å; F129-F311 HydrophobicContact CD2-CB 4.1Å; F129-F311 AromaticContact CD2-CD2 3.98Å; F129-F311 HydrophobicContact CD2-CD2 3.98Å; F129-F311 HydrophobicContact CE2-CB 4.28Å; F129-F311 AromaticContact CE2-CD2 3.57Å; F129-F311 HydrophobicContact CE2-CD2 3.57Å; F129-F311 HydrophobicContact CE2-CE2 4.4Å; F129-F311 HydrophobicContact CE2-CG 4.36Å; F129-F311 AromaticContact CZ-CD2 3.88Å; F129-F311 HydrophobicContact CZ-CD2 3.88Å; F129-F311 HydrophobicContact CZ-CE2 4.31Å
130	A	93	Very high	89.8	Confident	0 Å²	0	32.7 Å²	32.7	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-63.4	-43.1	-177.9	0	0	0	0	0	112.1	S126 M127 T128 Y132 I133 A134 V148 L151 A152	S126-A130 WeakPolarHBondContact O-CB 3.2Å; S126-A130 PolarHBondContact O-N 2.83Å; M127-A130 PolarHBondContact O-N 2.95Å; T128-A130 VanDerWaalsContact C-N 3.29Å; T128-A130 PolarHBondContact O-N 3.19Å; A130-Y132 VanDerWaalsContact C-N 3.34Å; A130-Y132 PolarHBondContact O-N 3.33Å; A130-I133 PolarHBondContact O-N 3.34Å; A130-A134 WeakPolarHBondContact O-CB 3.35Å; A130-A134 PolarHBondContact O-N 3.37Å; A130-V148 HydrophobicContact CB-CB 4.45Å; A130-V148 HydrophobicContact CB-CG1 3.74Å; A130-V148 WeakPolarHBondContact CB-O 3.5Å; A130-L151 HydrophobicContact CB-CB 3.89Å; A130-L151 HydrophobicContact CB-CD2 3.99Å; A130-L151 HydrophobicContact CB-CG 3.96Å; A130-A152 HydrophobicContact CB-CB 4.15Å
131	K	89.5	Confident	89.5	Confident	60 Å²	60	36.1 Å²	36.1	26%	0.261	20%	0.197	S	C	.	.	H	α-helix	trans	-61.1	-42.5	176.5	-73.9	-170	175.6	-173.6	0	112.3	M127 T128 F129 A134 Q135 Q143 V148 P284 I368	M127-K131 WeakPolarHBondContact O-CG 3.41Å; M127-K131 PolarHBondContact O-N 2.77Å; T128-K131 PolarHBondContact O-N 2.9Å; F129-K131 PolarHBondContact O-N 3.19Å; K131-A134 PolarHBondContact O-N 2.81Å; K131-Q135 WeakPolarHBondContact O-CB 3.42Å; K131-Q135 PolarHBondContact O-N 2.91Å; K131-Q143 VanDerWaalsContact CA-OE1 3.25Å; K131-Q143 PolarHBondContact O-NE2 3.01Å; K131-V148 HydrophobicContact CG-CG1 3.76Å; K131-V148 HydrophobicContact CG-CG2 4.44Å; K131-P284 HydrophobicContact CD-CB 4.41Å; K131-I368 HydrophobicContact CD-CD1 3.75Å
132	Y	89.6	Confident	89.1	Confident	2 Å²	2	43 Å²	43	1%	0.008	23%	0.233	C	C	.	.	H	α-helix	trans	-71.6	-37	-178.8	-88.1	-98.5	0	0	0	113.3	F46 T128 F129 A130 P136 A285 A287 I288 V306	F46-Y132 HydrophobicContact CB-CE2 4.29Å; F46-Y132 PolarHBondContact O-OH 3.43Å; T128-Y132 HydrophobicContact CG2-CD2 3.82Å; T128-Y132 HydrophobicContact CG2-CE2 3.89Å; T128-Y132 VanDerWaalsContact O-CD2 3.31Å; T128-Y132 WeakPolarHBondContact O-CD2 3.17Å; T128-Y132 PolarHBondContact O-N 3.2Å; F129-Y132 PolarHBondContact O-N 3.38Å; A130-Y132 VanDerWaalsContact C-N 3.34Å; A130-Y132 PolarHBondContact O-N 3.33Å; Y132-P136 WeakPolarHBondContact O-CD 3.37Å; Y132-A285 HydrophobicContact CD1-CB 4.28Å; Y132-A285 HydrophobicContact CD2-CB 4.42Å; Y132-A285 HydrophobicContact CE1-CB 3.83Å; Y132-A285 HydrophobicContact CE2-CB 4Å; Y132-A285 WeakPolarHBondContact OH-CA 3.49Å; Y132-A287 HydrophobicContact CE1-CB 4.19Å; Y132-I288 HydrophobicContact CD1-CD1 3.55Å; Y132-I288 HydrophobicContact CD1-CG1 3.7Å; Y132-I288 HydrophobicContact CE1-CD1 4.04Å; Y132-I288 HydrophobicContact CE1-CG1 3.77Å; Y132-I288 HydrophobicContact CG-CD1 4.22Å; Y132-V306 HydrophobicContact CD1-CB 3.52Å; Y132-V306 HydrophobicContact CD1-CG1 3.33Å; Y132-V306 HydrophobicContact CD1-CG2 4.08Å; Y132-V306 HydrophobicContact CD2-CG1 3.97Å; Y132-V306 HydrophobicContact CE1-CB 3.81Å; Y132-V306 HydrophobicContact CE1-CG1 3.45Å; Y132-V306 VanDerWaalsContact CE1-CG1 3.45Å; Y132-V306 HydrophobicContact CE1-CG2 3.91Å; Y132-V306 HydrophobicContact CE2-CG1 4.06Å; Y132-V306 HydrophobicContact CG-CB 4.14Å; Y132-V306 HydrophobicContact CG-CG1 3.6Å
133	I	90.5	Very high	88.9	Confident	66 Å²	66	44.2 Å²	44.2	34%	0.338	24%	0.239	S	C	.	.	H	α-helix	trans	-71.9	-34.3	174.6	-75.5	-161.6	0	0	0	112.2	F129 A130 P136 L151 A307	F129-I133 HydrophobicContact CD2-CD1 4.11Å; F129-I133 HydrophobicContact CD2-CG1 4.42Å; F129-I133 HydrophobicContact CE1-CD1 4.07Å; F129-I133 HydrophobicContact CE2-CD1 3.28Å; F129-I133 HydrophobicContact CE2-CG1 4.04Å; F129-I133 HydrophobicContact CZ-CD1 3.27Å; F129-I133 HydrophobicContact CZ-CG1 4.25Å; F129-I133 PolarHBondContact O-N 3.43Å; A130-I133 PolarHBondContact O-N 3.34Å; I133-P136 WeakPolarHBondContact O-CD 3.05Å; I133-L151 HydrophobicContact CB-CD2 4.28Å; I133-L151 HydrophobicContact CG2-CD2 3.94Å; I133-A307 HydrophobicContact CD1-CB 3.91Å; I133-A307 HydrophobicContact CG1-CB 3.48Å; I133-A307 VanDerWaalsContact CG1-CB 3.48Å
134	A	90	Very high	88.7	Confident	10 Å²	10	47.2 Å²	47.2	8%	0.083	26%	0.258	C	S	.	.	H	α-helix	trans	-77.9	-27.2	-178.8	0	0	0	0	0	112.8	A130 K131 I137 F138 Q143	A130-A134 WeakPolarHBondContact O-CB 3.35Å; A130-A134 PolarHBondContact O-N 3.37Å; K131-A134 PolarHBondContact O-N 2.81Å; A134-I137 WeakPolarHBondContact O-CA 3.3Å; A134-I137 WeakPolarHBondContact O-CB 3.34Å; A134-I137 PolarHBondContact O-N 2.88Å; A134-F138 HydrophobicContact CB-CD2 4.4Å; A134-F138 WeakPolarHBondContact O-CD2 3.42Å; A134-F138 PolarHBondContact O-N 3.11Å; A134-F138 VanDerWaalsContact O-N 3.16Å; A134-Q143 HydrophobicContact CB-CG 4.19Å
135	Q	85.2	Confident	88.7	Confident	28 Å²	28	52.6 Å²	52.6	13%	0.131	28%	0.283	C	S	.	.	T	Hydrogen-bonded Turn	trans	-55.2	-41.9	-174.8	-169.6	68.8	22.7	0	0	114	K131 I137 F138 Q143 I288	K131-Q135 WeakPolarHBondContact O-CB 3.42Å; K131-Q135 PolarHBondContact O-N 2.91Å; Q135-I137 PolarHBondContact O-N 3.31Å; Q135-F138 CarbonylContact O-C 3.6Å; Q135-F138 PolarHBondContact O-N 3.49Å; Q135-Q143 VanDerWaalsContact CA-NE2 3.28Å; Q135-Q143 VanDerWaalsContact N-NE2 3.16Å; Q135-I288 HydrophobicContact CB-CD1 3.54Å; Q135-I288 HydrophobicContact CG-CD1 3.84Å; Q135-I288 HydrophobicContact CG-CG2 4.19Å
136	P	84.3	Confident	88.7	Confident	50 Å²	50	57 Å²	57	33%	0.325	31%	0.311	S	S	.	.	T	Hydrogen-bonded Turn	trans	-58.9	-28.1	173.8	-28.7	37.4	0	0	0	115.5	Y132 I133 W299 P303	Y132-P136 WeakPolarHBondContact O-CD 3.37Å; I133-P136 WeakPolarHBondContact O-CD 3.05Å; P136-W299 HydrophobicContact CB-CH2 3.62Å; P136-W299 HydrophobicContact CB-CZ3 4.14Å; P136-W299 HydrophobicContact CG-CH2 3.95Å; P136-W299 HydrophobicContact CG-CZ3 3.94Å; P136-P303 HydrophobicContact CG-CB 4.1Å; P136-P303 HydrophobicContact CG-CG 4.03Å
137	I	88.5	Confident	88.6	Confident	119 Å²	119	59.2 Å²	59.2	61%	0.61	33%	0.329	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.6	-29.7	-179.1	-55.5	171.7	0	0	0	110.2	A134 Q135 P139	A134-I137 WeakPolarHBondContact O-CA 3.3Å; A134-I137 WeakPolarHBondContact O-CB 3.34Å; A134-I137 PolarHBondContact O-N 2.88Å; Q135-I137 PolarHBondContact O-N 3.31Å; I137-P139 VanDerWaalsContact C-CD 3.4Å; I137-P139 WeakPolarHBondContact O-CD 3.17Å
138	F	87.4	Confident	88.7	Confident	60 Å²	60	59.3 Å²	59.3	26%	0.263	33%	0.33	S	S	.	.	S	Bend	trans	-121.9	66.9	179.1	-57.9	-84.6	0	0	0	110.2	A134 Q135 Q143 P144	A134-F138 HydrophobicContact CB-CD2 4.4Å; A134-F138 WeakPolarHBondContact O-CD2 3.42Å; A134-F138 PolarHBondContact O-N 3.11Å; A134-F138 VanDerWaalsContact O-N 3.16Å; Q135-F138 CarbonylContact O-C 3.6Å; Q135-F138 PolarHBondContact O-N 3.49Å; F138-Q143 HydrophobicContact CB-CG 4.06Å; F138-Q143 HydrophobicContact CD2-CG 4.21Å; F138-Q143 HydrophobicContact CG-CG 4.39Å; F138-P144 HydrophobicContact CE1-CG 4.2Å; F138-P144 HydrophobicContact CZ-CG 4.13Å
139	P	79.4	Confident	88.8	Confident	77 Å²	77	62.2 Å²	62.2	50%	0.5	34%	0.341	S	S	.	.	S	Bend	trans	-67.5	-39.6	-172.3	25.1	-33.3	0	0	0	112.9	I137	I137-P139 VanDerWaalsContact C-CD 3.4Å; I137-P139 WeakPolarHBondContact O-CD 3.17Å
140	D	81.3	Confident	89	Confident	160 Å²	160	66.4 Å²	66.4	86%	0.856	36%	0.364	S	S	*	.	S	Bend	trans	-112.2	10.3	-171.8	-54.5	-54.3	0	0	0	113.3
141	C	86.3	Confident	89.1	Confident	72 Å²	72	69.1 Å²	69.1	49%	0.486	38%	0.378	S	S	.	.	S	Bend	trans	-142.5	156.4	-179	54.6	0	0	0	0	112.2	Q143	C141-Q143 PolarHBondContact O-N 3.28Å
142	D	83.4	Confident	89.5	Confident	154 Å²	154	66.2 Å²	66.2	82%	0.824	37%	0.365	S	S	*	.	P	Polyproline II helix	trans	-65.3	135.7	175.5	-69.7	-36	0	0	0	110.9
143	Q	88.6	Confident	89.8	Confident	27 Å²	27	67 Å²	67	13%	0.126	37%	0.372	C	S	.	.	P	Polyproline II helix	trans	-70.4	136.5	179.6	-58.3	167.2	5.4	0	0	109.8	K131 A134 Q135 F138 C141 E145 V148	K131-Q143 VanDerWaalsContact CA-OE1 3.25Å; K131-Q143 PolarHBondContact O-NE2 3.01Å; A134-Q143 HydrophobicContact CB-CG 4.19Å; Q135-Q143 VanDerWaalsContact CA-NE2 3.28Å; Q135-Q143 VanDerWaalsContact N-NE2 3.16Å; F138-Q143 HydrophobicContact CB-CG 4.06Å; F138-Q143 HydrophobicContact CD2-CG 4.21Å; F138-Q143 HydrophobicContact CG-CG 4.39Å; C141-Q143 PolarHBondContact O-N 3.28Å; Q143-E145 PolarHBondContact O-N 3.44Å; Q143-E145 VanDerWaalsContact O-N 3.15Å; Q143-V148 HydrophobicContact CB-CG2 3.8Å
144	P	92.2	Very high	90.2	Very high	63 Å²	63	68 Å²	68	41%	0.409	38%	0.381	S	S	.	.	P	Polyproline II helix	trans	-61.1	122.1	176.7	-18.5	29.3	0	0	0	110.6	F138 V146 A147 V148	F138-P144 HydrophobicContact CE1-CG 4.2Å; F138-P144 HydrophobicContact CZ-CG 4.13Å; P144-V146 VanDerWaalsContact C-N 3.26Å; P144-V146 PolarHBondContact O-N 3.07Å; P144-A147 HydrophobicContact CB-CB 4.12Å; P144-A147 WeakPolarHBondContact O-CA 3.48Å; P144-A147 WeakPolarHBondContact O-CB 3.38Å; P144-A147 PolarHBondContact O-N 2.78Å; P144-V148 PolarHBondContact O-N 2.97Å; P144-V148 VanDerWaalsContact O-N 3.14Å
145	E	90.4	Very high	90.4	Very high	112 Å²	112	67.7 Å²	67.7	52%	0.523	38%	0.378	S	S	.	.	H	α-helix	trans	-57.5	-39.5	-173.3	-173.1	179	-168.9	0	0	112.6	Q143 A147 V148 R149	Q143-E145 PolarHBondContact O-N 3.44Å; Q143-E145 VanDerWaalsContact O-N 3.15Å; E145-A147 VanDerWaalsContact C-N 3.3Å; E145-A147 PolarHBondContact O-N 2.92Å; E145-V148 PolarHBondContact O-N 2.95Å; E145-R149 WeakPolarHBondContact O-CG 3.17Å; E145-R149 PolarHBondContact O-N 2.82Å; E145-R149 IonicContact OE1-CZ 2.66Å; E145-R149 VanDerWaalsContact OE1-CZ 3.24Å; E145-R149 IonicContact OE1-NE 3.24Å; E145-R149 PolarHBondContact OE1-NE 2.93Å; E145-R149 IonicContact OE1-NH2 2.99Å; E145-R149 PolarHBondContact OE1-NH2 3.26Å
146	V	92.6	Very high	91	Very high	105 Å²	105	66.3 Å²	66.3	64%	0.636	37%	0.372	S	S	*	.	H	α-helix	trans	-61.3	-39.7	176.8	-179.6	0	0	0	0	111.2	P144 R149 L150	P144-V146 VanDerWaalsContact C-N 3.26Å; P144-V146 PolarHBondContact O-N 3.07Å; V146-R149 PolarHBondContact O-N 2.85Å; V146-L150 HydrophobicContact CG1-CD1 3.94Å; V146-L150 HydrophobicContact CG1-CG 4.32Å; V146-L150 WeakPolarHBondContact O-CB 3.35Å; V146-L150 VanDerWaalsContact O-CG 3.27Å; V146-L150 WeakPolarHBondContact O-CG 3.12Å; V146-L150 PolarHBondContact O-N 2.7Å
147	A	93.6	Very high	91.6	Very high	47 Å²	47	68.2 Å²	68.2	39%	0.388	38%	0.378	S	S	.	.	H	α-helix	trans	-67	-42.5	179.1	0	0	0	0	0	111	P144 E145 L150 L151	P144-A147 HydrophobicContact CB-CB 4.12Å; P144-A147 WeakPolarHBondContact O-CA 3.48Å; P144-A147 WeakPolarHBondContact O-CB 3.38Å; P144-A147 PolarHBondContact O-N 2.78Å; E145-A147 VanDerWaalsContact C-N 3.3Å; E145-A147 PolarHBondContact O-N 2.92Å; A147-L150 PolarHBondContact O-N 2.92Å; A147-L151 VanDerWaalsContact O-CB 3.32Å; A147-L151 WeakPolarHBondContact O-CB 3.43Å; A147-L151 PolarHBondContact O-N 2.98Å
148	V	93.1	Very high	91.9	Very high	10 Å²	10	66.6 Å²	66.6	6%	0.061	37%	0.37	C	S	.	.	H	α-helix	trans	-60.5	-47	175.3	177.7	0	0	0	0	110.6	A130 K131 Q143 P144 E145 L151 A152	A130-V148 HydrophobicContact CB-CB 4.45Å; A130-V148 HydrophobicContact CB-CG1 3.74Å; A130-V148 WeakPolarHBondContact CB-O 3.5Å; K131-V148 HydrophobicContact CG-CG1 3.76Å; K131-V148 HydrophobicContact CG-CG2 4.44Å; Q143-V148 HydrophobicContact CB-CG2 3.8Å; P144-V148 PolarHBondContact O-N 2.97Å; P144-V148 VanDerWaalsContact O-N 3.14Å; E145-V148 PolarHBondContact O-N 2.95Å; V148-L151 PolarHBondContact O-N 2.88Å; V148-A152 VanDerWaalsContact O-CB 3.31Å; V148-A152 WeakPolarHBondContact O-CB 3.27Å; V148-A152 PolarHBondContact O-N 3.43Å
149	R	94.7	Very high	92.2	Very high	63 Å²	63	63.7 Å²	63.7	24%	0.238	36%	0.358	C	S	.	.	H	α-helix	trans	-65.1	-41.1	179.3	-70.4	179.8	-176.4	-162.2	0	112.6	E145 V146 A152 A153 L363	E145-R149 WeakPolarHBondContact O-CG 3.17Å; E145-R149 PolarHBondContact O-N 2.82Å; E145-R149 IonicContact OE1-CZ 2.66Å; E145-R149 VanDerWaalsContact OE1-CZ 3.24Å; E145-R149 IonicContact OE1-NE 3.24Å; E145-R149 PolarHBondContact OE1-NE 2.93Å; E145-R149 IonicContact OE1-NH2 2.99Å; E145-R149 PolarHBondContact OE1-NH2 3.26Å; V146-R149 PolarHBondContact O-N 2.85Å; R149-A152 PolarHBondContact O-N 3.36Å; R149-A153 WeakPolarHBondContact O-CB 3.25Å; R149-A153 PolarHBondContact O-N 3.11Å; R149-L363 WeakPolarHBondContact CD-O 3.28Å; R149-L363 PolarHBondContact NE-O 3.48Å
150	L	95.9	Very high	92.8	Very high	110 Å²	110	60.4 Å²	60.4	58%	0.576	34%	0.336	S	S	*	.	H	α-helix	trans	-65.3	-44.1	176.1	-73.1	173.8	0	0	0	111.5	V146 A147 A152 A153 V154	V146-L150 HydrophobicContact CG1-CD1 3.94Å; V146-L150 HydrophobicContact CG1-CG 4.32Å; V146-L150 WeakPolarHBondContact O-CB 3.35Å; V146-L150 VanDerWaalsContact O-CG 3.27Å; V146-L150 WeakPolarHBondContact O-CG 3.12Å; V146-L150 PolarHBondContact O-N 2.7Å; A147-L150 PolarHBondContact O-N 2.92Å; L150-A152 VanDerWaalsContact C-N 3.32Å; L150-A152 PolarHBondContact O-N 3.05Å; L150-A153 WeakPolarHBondContact O-CB 3.25Å; L150-A153 PolarHBondContact O-N 3.22Å; L150-V154 WeakPolarHBondContact O-CG2 3.32Å; L150-V154 PolarHBondContact O-N 3.27Å
151	L	95.7	Very high	93.4	Very high	56 Å²	56	59 Å²	59	29%	0.293	32%	0.323	S	S	.	.	H	α-helix	trans	-64.6	-38.1	177	-175.8	60.7	0	0	0	111.7	F129 A130 I133 A147 V148 V154 C155	F129-L151 HydrophobicContact CE1-CD1 4.41Å; F129-L151 HydrophobicContact CE1-CG 4.23Å; A130-L151 HydrophobicContact CB-CB 3.89Å; A130-L151 HydrophobicContact CB-CD2 3.99Å; A130-L151 HydrophobicContact CB-CG 3.96Å; I133-L151 HydrophobicContact CB-CD2 4.28Å; I133-L151 HydrophobicContact CG2-CD2 3.94Å; A147-L151 VanDerWaalsContact O-CB 3.32Å; A147-L151 WeakPolarHBondContact O-CB 3.43Å; A147-L151 PolarHBondContact O-N 2.98Å; V148-L151 PolarHBondContact O-N 2.88Å; L151-V154 PolarHBondContact O-N 2.82Å; L151-C155 PolarHBondContact O-N 3.48Å
152	A	96.2	Very high	93.6	Very high	0 Å²	0	56.9 Å²	56.9	0%	0	31%	0.306	C	S	.	.	H	α-helix	trans	-61.5	-44.3	171.7	0	0	0	0	0	111.4	S126 M127 A130 V148 R149 L150 V154 C155 I156 L363	S126-A152 WeakPolarHBondContact O-CB 3.3Å; M127-A152 HydrophobicContact CG-CB 4.08Å; A130-A152 HydrophobicContact CB-CB 4.15Å; V148-A152 VanDerWaalsContact O-CB 3.31Å; V148-A152 WeakPolarHBondContact O-CB 3.27Å; V148-A152 PolarHBondContact O-N 3.43Å; R149-A152 PolarHBondContact O-N 3.36Å; L150-A152 VanDerWaalsContact C-N 3.32Å; L150-A152 PolarHBondContact O-N 3.05Å; A152-V154 PolarHBondContact O-N 3.39Å; A152-C155 WeakPolarHBondContact O-CB 3.31Å; A152-C155 PolarHBondContact O-N 2.84Å; A152-I156 WeakPolarHBondContact O-CG1 3.25Å; A152-I156 PolarHBondContact O-N 3.21Å; A152-L363 HydrophobicContact CB-CD1 4.12Å; A152-L363 HydrophobicContact CB-CD2 3.84Å
153	A	97.3	Very high	93.8	Very high	18 Å²	18	50 Å²	50	15%	0.149	27%	0.269	C	S	.	.	H	α-helix	trans	-61.9	-42	176.4	0	0	0	0	0	112	R149 L150 C155 I156 I157 L363	R149-A153 WeakPolarHBondContact O-CB 3.25Å; R149-A153 PolarHBondContact O-N 3.11Å; L150-A153 WeakPolarHBondContact O-CB 3.25Å; L150-A153 PolarHBondContact O-N 3.22Å; A153-C155 VanDerWaalsContact C-N 3.31Å; A153-C155 PolarHBondContact O-N 2.86Å; A153-I156 PolarHBondContact O-N 3.4Å; A153-I157 WeakPolarHBondContact O-CB 3.29Å; A153-I157 VanDerWaalsContact O-CG1 3.24Å; A153-I157 WeakPolarHBondContact O-CG1 3.4Å; A153-I157 PolarHBondContact O-N 2.96Å; A153-L363 HydrophobicContact CB-CD1 3.72Å
154	V	97.3	Very high	93.8	Very high	87 Å²	87	49.4 Å²	49.4	53%	0.527	27%	0.27	S	S	.	.	H	α-helix	trans	-59.2	-43.6	174	173.9	0	0	0	0	110.9	L150 L151 A152 I157 L158	L150-V154 WeakPolarHBondContact O-CG2 3.32Å; L150-V154 PolarHBondContact O-N 3.27Å; L151-V154 PolarHBondContact O-N 2.82Å; A152-V154 PolarHBondContact O-N 3.39Å; V154-I157 PolarHBondContact O-N 3.24Å; V154-L158 WeakPolarHBondContact O-CB 3.29Å; V154-L158 PolarHBondContact O-N 2.92Å
155	C	95.7	Very high	93.7	Very high	3 Å²	3	50.5 Å²	50.5	2%	0.02	27%	0.268	C	S	.	.	H	α-helix	trans	-58	-49.1	175.5	177	0	0	0	0	112	F129 L151 A152 A153 L158 L159 F311	F129-C155 HydrophobicContact CD1-CB 3.63Å; F129-C155 HydrophobicContact CE1-CB 3.69Å; F129-C155 HydrophobicContact CG-CB 4.45Å; L151-C155 PolarHBondContact O-N 3.48Å; A152-C155 WeakPolarHBondContact O-CB 3.31Å; A152-C155 PolarHBondContact O-N 2.84Å; A153-C155 VanDerWaalsContact C-N 3.31Å; A153-C155 PolarHBondContact O-N 2.86Å; C155-L158 PolarHBondContact O-N 3.35Å; C155-L159 WeakPolarHBondContact O-CB 3.17Å; C155-L159 PolarHBondContact O-N 3.31Å; C155-F311 HydrophobicContact CB-CE2 4.5Å; C155-F311 WeakPolarHBondContact SG-CD2 3.26Å
156	I	96.3	Very high	93.4	Very high	0 Å²	0	46.5 Å²	46.5	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-60.8	-47.9	178	-62.6	174.8	0	0	0	111	V122 S126 A152 A153 L159 S160 C356 I360 L363	V122-I156 HydrophobicContact CG1-CD1 3.9Å; V122-I156 HydrophobicContact CG1-CG1 3.76Å; V122-I156 HydrophobicContact CG1-CG2 4.25Å; S126-I156 WeakPolarHBondContact OG-CG1 3.35Å; A152-I156 WeakPolarHBondContact O-CG1 3.25Å; A152-I156 PolarHBondContact O-N 3.21Å; A153-I156 PolarHBondContact O-N 3.4Å; I156-L159 PolarHBondContact O-N 2.92Å; I156-S160 WeakPolarHBondContact O-CB 3.34Å; I156-S160 PolarHBondContact O-N 3.27Å; I156-S160 PolarHBondContact O-OG 2.88Å; I156-C356 HydrophobicContact CG2-CB 4.45Å; I156-I360 HydrophobicContact CG2-CG1 4.33Å; I156-L363 HydrophobicContact CD1-CD1 3.78Å; I156-L363 HydrophobicContact CD1-CD2 4.24Å; I156-L363 HydrophobicContact CD1-CG 4.05Å
157	I	97.3	Very high	92.7	Very high	90 Å²	90	44.3 Å²	44.3	46%	0.462	24%	0.239	S	C	.	.	H	α-helix	trans	-63.9	-45.8	-177.3	-68.8	166.5	0	0	0	110.3	A153 V154 S160 F161 I360	A153-I157 WeakPolarHBondContact O-CB 3.29Å; A153-I157 VanDerWaalsContact O-CG1 3.24Å; A153-I157 WeakPolarHBondContact O-CG1 3.4Å; A153-I157 PolarHBondContact O-N 2.96Å; V154-I157 PolarHBondContact O-N 3.24Å; I157-S160 PolarHBondContact O-N 3.46Å; I157-F161 WeakPolarHBondContact O-CB 3.36Å; I157-F161 PolarHBondContact O-N 2.87Å; I157-I360 HydrophobicContact CD1-CD1 4.16Å; I157-I360 HydrophobicContact CG1-CD1 3.88Å
158	L	95.2	Very high	92.1	Very high	84 Å²	84	52.5 Å²	52.5	44%	0.44	26%	0.26	S	S	.	.	H	α-helix	trans	-61.9	-47.5	179.8	-180	62.5	0	0	0	111.4	V154 C155 F161 I162 F311	V154-L158 WeakPolarHBondContact O-CB 3.29Å; V154-L158 PolarHBondContact O-N 2.92Å; C155-L158 PolarHBondContact O-N 3.35Å; L158-F161 WeakPolarHBondContact O-CB 3.47Å; L158-F161 PolarHBondContact O-N 2.82Å; L158-I162 HydrophobicContact CD1-CD1 4.4Å; L158-I162 HydrophobicContact CG-CD1 4.2Å; L158-I162 WeakPolarHBondContact O-CG1 3.48Å; L158-I162 PolarHBondContact O-N 2.75Å; L158-F311 HydrophobicContact CD2-CE2 4.33Å; L158-F311 HydrophobicContact CD2-CZ 3.96Å; L158-F311 HydrophobicContact CG-CZ 4.46Å
159	L	92.9	Very high	91.5	Very high	0 Å²	0	56.5 Å²	56.5	0%	0	28%	0.279	C	S	.	.	H	α-helix	trans	-68.1	-38.5	178.9	-79.5	174.2	0	0	0	112.7	C155 I156 F161 I162 N163 F311 V314 N315	C155-L159 WeakPolarHBondContact O-CB 3.17Å; C155-L159 PolarHBondContact O-N 3.31Å; I156-L159 PolarHBondContact O-N 2.92Å; L159-F161 VanDerWaalsContact C-N 3.3Å; L159-F161 PolarHBondContact O-N 3.1Å; L159-I162 HydrophobicContact CD2-CD1 4.39Å; L159-I162 PolarHBondContact O-N 2.82Å; L159-N163 WeakPolarHBondContact O-CB 3.39Å; L159-N163 PolarHBondContact O-N 3.47Å; L159-N163 PolarHBondContact O-ND2 3.32Å; L159-F311 HydrophobicContact CD1-CD1 3.7Å; L159-F311 HydrophobicContact CD1-CD2 4.09Å; L159-F311 HydrophobicContact CD1-CE1 3.78Å; L159-F311 HydrophobicContact CD1-CE2 4.09Å; L159-F311 HydrophobicContact CD1-CG 3.91Å; L159-F311 HydrophobicContact CD1-CZ 3.95Å; L159-F311 VanDerWaalsContact CD1-O 3.29Å; L159-F311 WeakPolarHBondContact CD1-O 3.39Å; L159-F311 HydrophobicContact CD2-CD1 3.64Å; L159-F311 HydrophobicContact CD2-CE1 3.09Å; L159-F311 HydrophobicContact CD2-CZ 3.62Å; L159-F311 HydrophobicContact CG-CD1 3.95Å; L159-F311 HydrophobicContact CG-CE1 3.48Å; L159-F311 VanDerWaalsContact CG-CE1 3.48Å; L159-F311 HydrophobicContact CG-CE2 4.06Å; L159-F311 HydrophobicContact CG-CG 4.49Å; L159-F311 HydrophobicContact CG-CZ 3.52Å; L159-V314 HydrophobicContact CB-CG1 4.26Å; L159-V314 HydrophobicContact CD1-CB 3.5Å; L159-V314 VanDerWaalsContact CD1-CB 3.5Å; L159-V314 HydrophobicContact CD1-CG1 3.38Å; L159-V314 HydrophobicContact CG-CG1 4.47Å; L159-N315 HydrophobicContact CD1-CB 4.3Å; L159-N315 HydrophobicContact CD2-CB 3.74Å
160	S	93.3	Very high	90.7	Very high	7 Å²	7	53.5 Å²	53.5	5%	0.049	27%	0.268	C	S	.	.	H	α-helix	trans	-62.8	-40.6	173.5	-61.1	0	0	0	0	110.7	I156 I157 N163 A164 V352 C356	I156-S160 WeakPolarHBondContact O-CB 3.34Å; I156-S160 PolarHBondContact O-N 3.27Å; I156-S160 PolarHBondContact O-OG 2.88Å; I157-S160 PolarHBondContact O-N 3.46Å; S160-N163 PolarHBondContact O-N 2.96Å; S160-A164 VanDerWaalsContact O-CB 3.28Å; S160-A164 WeakPolarHBondContact O-CB 3.12Å; S160-A164 PolarHBondContact O-N 3.4Å; S160-V352 WeakPolarHBondContact O-CG1 3.48Å; S160-C356 WeakPolarHBondContact OG-CB 3.49Å
161	F	93.6	Very high	89.8	Confident	130 Å²	130	50.8 Å²	50.8	57%	0.57	26%	0.256	S	S	*	.	H	α-helix	trans	-62	-46.3	174.3	177.2	-97.9	0	0	0	111.9	I157 L158 L159 N163 A164 F165	I157-F161 WeakPolarHBondContact O-CB 3.36Å; I157-F161 PolarHBondContact O-N 2.87Å; L158-F161 WeakPolarHBondContact O-CB 3.47Å; L158-F161 PolarHBondContact O-N 2.82Å; L159-F161 VanDerWaalsContact C-N 3.3Å; L159-F161 PolarHBondContact O-N 3.1Å; F161-N163 VanDerWaalsContact C-N 3.34Å; F161-N163 PolarHBondContact O-N 3.39Å; F161-A164 PolarHBondContact O-N 3.49Å; F161-F165 HydrophobicContact CZ-CD2 4.35Å; F161-F165 VanDerWaalsContact O-CB 3.26Å; F161-F165 WeakPolarHBondContact O-CB 3.39Å; F161-F165 PolarHBondContact O-N 3.47Å
162	I	90.7	Very high	89.2	Confident	28 Å²	28	54.5 Å²	54.5	14%	0.144	27%	0.27	C	S	.	.	H	α-helix	trans	-59.5	-45.5	177.3	-67.8	164.9	0	0	0	110.8	L158 L159 A164 F165 S166 M169	L158-I162 HydrophobicContact CD1-CD1 4.4Å; L158-I162 HydrophobicContact CG-CD1 4.2Å; L158-I162 WeakPolarHBondContact O-CG1 3.48Å; L158-I162 PolarHBondContact O-N 2.75Å; L159-I162 HydrophobicContact CD2-CD1 4.39Å; L159-I162 PolarHBondContact O-N 2.82Å; I162-A164 PolarHBondContact O-N 3.31Å; I162-F165 PolarHBondContact O-N 2.94Å; I162-S166 PolarHBondContact O-N 2.93Å; I162-M169 HydrophobicContact CG2-CB 4.2Å
163	N	87.7	Confident	88.4	Confident	9 Å²	9	55.6 Å²	55.6	5%	0.048	28%	0.277	C	S	.	.	H	α-helix	trans	-65.6	-36.3	177.9	-81.9	-84.1	0	0	0	112.9	L159 S160 F161 S170 N315 V318 V352	L159-N163 WeakPolarHBondContact O-CB 3.39Å; L159-N163 PolarHBondContact O-N 3.47Å; L159-N163 PolarHBondContact O-ND2 3.32Å; S160-N163 PolarHBondContact O-N 2.96Å; F161-N163 VanDerWaalsContact C-N 3.34Å; F161-N163 PolarHBondContact O-N 3.39Å; N163-S170 WeakPolarHBondContact OD1-CB 3.48Å; N163-S170 PolarHBondContact OD1-OG 3.48Å; N163-N315 PolarHBondContact ND2-OD1 2.93Å; N163-V318 HydrophobicContact CB-CG1 3.93Å; N163-V352 HydrophobicContact CB-CG1 4.26Å; N163-V352 HydrophobicContact CB-CG2 4.23Å
164	A	88.6	Confident	87.5	Confident	16 Å²	16	56.2 Å²	56.2	13%	0.132	28%	0.276	C	S	.	.	H	α-helix	trans	-71.5	-31.4	174.9	0	0	0	0	0	112.2	S160 F161 I162 T347 I349 V352	S160-A164 VanDerWaalsContact O-CB 3.28Å; S160-A164 WeakPolarHBondContact O-CB 3.12Å; S160-A164 PolarHBondContact O-N 3.4Å; F161-A164 PolarHBondContact O-N 3.49Å; I162-A164 PolarHBondContact O-N 3.31Å; A164-T347 VanDerWaalsContact O-CB 3.25Å; A164-T347 WeakPolarHBondContact O-CB 3.5Å; A164-T347 PolarHBondContact O-OG1 2.88Å; A164-I349 HydrophobicContact CB-CG1 4.13Å; A164-I349 HydrophobicContact CB-CG2 4.39Å; A164-V352 HydrophobicContact CB-CG1 4.35Å
165	F	89.8	Confident	86.6	Confident	86 Å²	86	55.8 Å²	55.8	38%	0.377	27%	0.271	S	S	.	.	H	α-helix	trans	-83	-45.8	-175.7	-173.5	-99.1	0	0	0	113.4	F161 I162 M169 R345	F161-F165 HydrophobicContact CZ-CD2 4.35Å; F161-F165 VanDerWaalsContact O-CB 3.26Å; F161-F165 WeakPolarHBondContact O-CB 3.39Å; F161-F165 PolarHBondContact O-N 3.47Å; I162-F165 PolarHBondContact O-N 2.94Å; F165-M169 HydrophobicContact CD1-SD 4.03Å; F165-M169 HydrophobicContact CE1-SD 4.21Å; F165-R345 WeakPolarHBondContact O-CD 3.32Å
166	S	85	Confident	85.9	Confident	27 Å²	27	59.3 Å²	59.3	19%	0.189	29%	0.289	C	S	.	.			trans	-157.6	119.3	-177.3	177.4	0	0	0	0	112.9	I162 R168 M169 S170	I162-S166 PolarHBondContact O-N 2.93Å; S166-R168 VanDerWaalsContact C-N 3.26Å; S166-R168 PolarHBondContact O-N 3.43Å; S166-R168 PolarHBondContact OG-N 3.22Å; S166-M169 PolarHBondContact O-N 3.27Å; S166-M169 PolarHBondContact OG-N 2.91Å; S166-S170 PolarHBondContact O-N 2.87Å
167	V	77.2	Confident	85.3	Confident	60 Å²	60	60.5 Å²	60.5	36%	0.364	30%	0.295	S	S	.	.	H	α-helix	trans	-59.3	-39.6	172.2	-174.3	0	0	0	0	110.8	M169 S170 T171 M319 T347	V167-M169 PolarHBondContact O-N 3.25Å; V167-S170 WeakPolarHBondContact O-CB 3.31Å; V167-S170 PolarHBondContact O-N 2.92Å; V167-T171 PolarHBondContact O-N 3Å; V167-T171 PolarHBondContact O-OG1 3.49Å; V167-T171 VanDerWaalsContact O-OG1 3.06Å; V167-M319 HydrophobicContact CG1-CE 4.14Å; V167-T347 HydrophobicContact CG2-CG2 3.72Å
168	R	80.5	Confident	84.4	Confident	218 Å²	218	57.6 Å²	57.6	82%	0.823	28%	0.281	S	S	*	.	H	α-helix	trans	-64.4	-39.7	-179.5	-172.6	177.5	-178.9	171.9	0.6	112.2	S166 F172	S166-R168 VanDerWaalsContact C-N 3.26Å; S166-R168 PolarHBondContact O-N 3.43Å; S166-R168 PolarHBondContact OG-N 3.22Å; R168-F172 WeakPolarHBondContact O-CB 3.38Å; R168-F172 PolarHBondContact O-N 3.17Å
169	M	80	Confident	83.7	Confident	94 Å²	94	62.2 Å²	62.2	46%	0.463	29%	0.294	S	S	.	.	H	α-helix	trans	-66.1	-44.6	174.1	-69.8	-176.2	71.9	0	0	110.7	I162 F165 S166 V167 T171 F172 V173	I162-M169 HydrophobicContact CG2-CB 4.2Å; F165-M169 HydrophobicContact CD1-SD 4.03Å; F165-M169 HydrophobicContact CE1-SD 4.21Å; S166-M169 PolarHBondContact O-N 3.27Å; S166-M169 PolarHBondContact OG-N 2.91Å; V167-M169 PolarHBondContact O-N 3.25Å; M169-T171 VanDerWaalsContact C-N 3.34Å; M169-T171 PolarHBondContact O-N 3.38Å; M169-F172 PolarHBondContact O-N 3.35Å; M169-V173 VanDerWaalsContact O-CB 3.3Å; M169-V173 WeakPolarHBondContact O-CB 3.27Å; M169-V173 WeakPolarHBondContact O-CG2 3.45Å; M169-V173 PolarHBondContact O-N 2.99Å
170	S	77.9	Confident	83.1	Confident	0 Å²	0	62.8 Å²	62.8	0%	0	30%	0.298	C	S	.	.	H	α-helix	trans	-57	-45.6	176.3	179.4	0	0	0	0	112.1	N163 S166 V167 V173 Q174 N315	N163-S170 WeakPolarHBondContact OD1-CB 3.48Å; N163-S170 PolarHBondContact OD1-OG 3.48Å; S166-S170 PolarHBondContact O-N 2.87Å; V167-S170 WeakPolarHBondContact O-CB 3.31Å; V167-S170 PolarHBondContact O-N 2.92Å; S170-V173 PolarHBondContact O-N 3.4Å; S170-Q174 WeakPolarHBondContact O-CB 3.48Å; S170-Q174 PolarHBondContact O-N 2.91Å; S170-N315 PolarHBondContact O-ND2 3.24Å; S170-N315 PolarHBondContact OG-ND2 3.31Å; S170-N315 PolarHBondContact OG-OD1 2.93Å; S170-N315 VanDerWaalsContact OG-OD1 3.09Å
171	T	78.3	Confident	82.6	Confident	54 Å²	54	62.7 Å²	62.7	33%	0.331	30%	0.297	S	S	.	.	H	α-helix	trans	-63	-46.5	176.4	-52.4	0	0	0	0	112	V167 M169 V173 Q174 D175	V167-T171 PolarHBondContact O-N 3Å; V167-T171 PolarHBondContact O-OG1 3.49Å; V167-T171 VanDerWaalsContact O-OG1 3.06Å; M169-T171 VanDerWaalsContact C-N 3.34Å; M169-T171 PolarHBondContact O-N 3.38Å; T171-V173 VanDerWaalsContact C-N 3.33Å; T171-V173 PolarHBondContact O-N 2.84Å; T171-Q174 VanDerWaalsContact O-CB 3.3Å; T171-Q174 WeakPolarHBondContact O-CB 3.38Å; T171-Q174 PolarHBondContact O-N 3.5Å; T171-Q174 VanDerWaalsContact O-N 3.15Å; T171-D175 PolarHBondContact O-N 3.44Å
172	F	81.3	Confident	82	Confident	133 Å²	133	59.2 Å²	59.2	58%	0.583	29%	0.287	S	S	*	.	H	α-helix	trans	-61.1	-43.2	179	176.5	-105	0	0	0	112.3	R168 M169 Q174 D175 I176	R168-F172 WeakPolarHBondContact O-CB 3.38Å; R168-F172 PolarHBondContact O-N 3.17Å; M169-F172 PolarHBondContact O-N 3.35Å; F172-Q174 VanDerWaalsContact C-N 3.32Å; F172-D175 PolarHBondContact O-N 3.3Å; F172-I176 HydrophobicContact CD1-CD1 3.96Å; F172-I176 HydrophobicContact CE1-CD1 3.39Å; F172-I176 HydrophobicContact CE2-CD1 4.15Å; F172-I176 HydrophobicContact CZ-CD1 3.51Å; F172-I176 HydrophobicContact CZ-CG1 4.4Å; F172-I176 PolarHBondContact O-N 2.66Å
173	V	79.5	Confident	81.7	Confident	23 Å²	23	60 Å²	60	14%	0.139	30%	0.297	C	S	.	.	H	α-helix	trans	-61.5	-42.2	175.1	169.8	0	0	0	0	110.4	M169 S170 T171 D175 F177	M169-V173 VanDerWaalsContact O-CB 3.3Å; M169-V173 WeakPolarHBondContact O-CB 3.27Å; M169-V173 WeakPolarHBondContact O-CG2 3.45Å; M169-V173 PolarHBondContact O-N 2.99Å; S170-V173 PolarHBondContact O-N 3.4Å; T171-V173 VanDerWaalsContact C-N 3.33Å; T171-V173 PolarHBondContact O-N 2.84Å; V173-D175 PolarHBondContact O-N 2.6Å; V173-F177 HydrophobicContact CB-CE2 4.38Å; V173-F177 HydrophobicContact CG1-CD2 3.72Å; V173-F177 HydrophobicContact CG1-CE2 3.11Å; V173-F177 HydrophobicContact CG1-CZ 3.83Å; V173-F177 WeakPolarHBondContact O-CD2 3.36Å; V173-F177 VanDerWaalsContact O-CG 3.29Å; V173-F177 WeakPolarHBondContact O-CG 3.24Å; V173-F177 PolarHBondContact O-N 2.75Å
174	Q	80.2	Confident	81.7	Confident	31 Å²	31	59.6 Å²	59.6	15%	0.145	30%	0.295	C	S	.	.	H	α-helix	trans	-59.9	-43.8	175.4	-169.1	63.7	30.2	0	0	112.8	S170 T171 F172 F177 T178 G312 N315	S170-Q174 WeakPolarHBondContact O-CB 3.48Å; S170-Q174 PolarHBondContact O-N 2.91Å; T171-Q174 VanDerWaalsContact O-CB 3.3Å; T171-Q174 WeakPolarHBondContact O-CB 3.38Å; T171-Q174 PolarHBondContact O-N 3.5Å; T171-Q174 VanDerWaalsContact O-N 3.15Å; F172-Q174 VanDerWaalsContact C-N 3.32Å; Q174-F177 PolarHBondContact O-N 3.22Å; Q174-T178 WeakPolarHBondContact O-CB 3.47Å; Q174-T178 PolarHBondContact O-N 2.64Å; Q174-T178 PolarHBondContact O-OG1 3.28Å; Q174-G312 PolarHBondContact NE2-O 3.49Å; Q174-G312 PolarHBondContact OE1-O 3.09Å; Q174-N315 PolarHBondContact OE1-ND2 2.8Å
175	D	77	Confident	81.8	Confident	79 Å²	79	59 Å²	59	42%	0.422	29%	0.289	S	S	.	.	H	α-helix	trans	-63.3	-49.1	-177	-69.7	-19.9	0	0	0	110.8	T171 F172 V173 F177 T178 Y179	T171-D175 PolarHBondContact O-N 3.44Å; F172-D175 PolarHBondContact O-N 3.3Å; V173-D175 PolarHBondContact O-N 2.6Å; D175-F177 VanDerWaalsContact C-N 3.32Å; D175-F177 PolarHBondContact O-N 3.14Å; D175-T178 WeakPolarHBondContact O-CB 3.39Å; D175-T178 PolarHBondContact O-N 3.49Å; D175-T178 VanDerWaalsContact O-N 3.12Å; D175-Y179 HydrophobicContact CB-CE2 4.39Å; D175-Y179 WeakPolarHBondContact O-CD2 3.33Å; D175-Y179 WeakPolarHBondContact O-CE2 3.32Å; D175-Y179 PolarHBondContact O-N 3.07Å
176	I	82.3	Confident	81.9	Confident	76 Å²	76	59 Å²	59	39%	0.39	29%	0.293	S	S	.	.	H	α-helix	trans	-55.3	-48.4	178	-68.5	169.1	0	0	0	111	F172 T178 Y179 A180	F172-I176 HydrophobicContact CD1-CD1 3.96Å; F172-I176 HydrophobicContact CE1-CD1 3.39Å; F172-I176 HydrophobicContact CE2-CD1 4.15Å; F172-I176 HydrophobicContact CZ-CD1 3.51Å; F172-I176 HydrophobicContact CZ-CG1 4.4Å; F172-I176 PolarHBondContact O-N 2.66Å; I176-T178 VanDerWaalsContact C-N 3.26Å; I176-T178 PolarHBondContact O-N 3.48Å; I176-Y179 PolarHBondContact O-N 3.37Å; I176-A180 PolarHBondContact O-N 3.36Å
177	F	82.9	Confident	82.2	Confident	26 Å²	26	60.5 Å²	60.5	11%	0.114	30%	0.297	C	S	.	.	H	α-helix	trans	-71.1	-24.5	-177	-60.7	-25.3	0	0	0	113.2	V173 Q174 D175 A180 K181 L308 F311	V173-F177 HydrophobicContact CB-CE2 4.38Å; V173-F177 HydrophobicContact CG1-CD2 3.72Å; V173-F177 HydrophobicContact CG1-CE2 3.11Å; V173-F177 HydrophobicContact CG1-CZ 3.83Å; V173-F177 WeakPolarHBondContact O-CD2 3.36Å; V173-F177 VanDerWaalsContact O-CG 3.29Å; V173-F177 WeakPolarHBondContact O-CG 3.24Å; V173-F177 PolarHBondContact O-N 2.75Å; Q174-F177 PolarHBondContact O-N 3.22Å; D175-F177 VanDerWaalsContact C-N 3.32Å; D175-F177 PolarHBondContact O-N 3.14Å; F177-A180 PolarHBondContact O-N 3.12Å; F177-K181 PolarHBondContact O-N 3.25Å; F177-L308 WeakPolarHBondContact CB-O 3.45Å; F177-L308 HydrophobicContact CD1-CB 3.86Å; F177-L308 HydrophobicContact CD1-CD2 3.81Å; F177-L308 HydrophobicContact CD1-CG 4.25Å; F177-L308 HydrophobicContact CE1-CB 4.34Å; F177-L308 HydrophobicContact CE1-CD2 3.37Å; F177-L308 HydrophobicContact CE1-CG 4.27Å; F177-L308 WeakPolarHBondContact CG-O 3.48Å; F177-L308 HydrophobicContact CZ-CD2 4.1Å; F177-F311 AromaticContact CD2-CD1 3.96Å; F177-F311 HydrophobicContact CD2-CD1 3.96Å; F177-F311 HydrophobicContact CE2-CB 4.5Å; F177-F311 AromaticContact CE2-CD1 3.25Å; F177-F311 HydrophobicContact CE2-CD1 3.25Å; F177-F311 AromaticContact CE2-CE1 3.73Å; F177-F311 HydrophobicContact CE2-CE1 3.73Å; F177-F311 HydrophobicContact CE2-CG 4.25Å; F177-F311 AromaticContact CZ-CD1 3.91Å; F177-F311 HydrophobicContact CZ-CD1 3.91Å; F177-F311 HydrophobicContact CZ-CE1 4.22Å
178	T	77.9	Confident	83	Confident	29 Å²	29	57.6 Å²	57.6	18%	0.178	28%	0.28	C	S	.	.	H	α-helix	trans	-69.3	-37.3	173.5	-60.3	0	0	0	0	111.8	Q174 D175 I176 K181 V182	Q174-T178 WeakPolarHBondContact O-CB 3.47Å; Q174-T178 PolarHBondContact O-N 2.64Å; Q174-T178 PolarHBondContact O-OG1 3.28Å; D175-T178 WeakPolarHBondContact O-CB 3.39Å; D175-T178 PolarHBondContact O-N 3.49Å; D175-T178 VanDerWaalsContact O-N 3.12Å; I176-T178 VanDerWaalsContact C-N 3.26Å; I176-T178 PolarHBondContact O-N 3.48Å; T178-K181 VanDerWaalsContact O-CG 3.24Å; T178-K181 WeakPolarHBondContact O-CG 3.41Å; T178-V182 WeakPolarHBondContact O-CG2 3.35Å; T178-V182 PolarHBondContact O-N 3.2Å
179	Y	80	Confident	83.6	Confident	180 Å²	180	48.3 Å²	48.3	71%	0.706	25%	0.246	S	C	*	.	H	α-helix	trans	-69.2	-40.8	173.4	-62.3	-65	0	0	0	112	D175 I176 K181 V182 A183	D175-Y179 HydrophobicContact CB-CE2 4.39Å; D175-Y179 WeakPolarHBondContact O-CD2 3.33Å; D175-Y179 WeakPolarHBondContact O-CE2 3.32Å; D175-Y179 PolarHBondContact O-N 3.07Å; I176-Y179 PolarHBondContact O-N 3.37Å; Y179-K181 PolarHBondContact O-N 3.18Å; Y179-V182 PolarHBondContact O-N 3.07Å; Y179-A183 WeakPolarHBondContact O-CB 3.33Å; Y179-A183 PolarHBondContact O-N 3.5Å
180	A	82.1	Confident	84.4	Confident	12 Å²	12	48.5 Å²	48.5	10%	0.099	25%	0.248	C	C	.	.	H	α-helix	trans	-59	-44.3	179.9	0	0	0	0	0	112.7	I176 F177 A183 A184 L308	I176-A180 PolarHBondContact O-N 3.36Å; F177-A180 PolarHBondContact O-N 3.12Å; A180-A183 PolarHBondContact O-N 3.29Å; A180-A184 PolarHBondContact O-N 3.01Å; A180-L308 HydrophobicContact CB-CB 4.09Å; A180-L308 HydrophobicContact CB-CD1 4.16Å
181	K	81.3	Confident	85.2	Confident	5 Å²	5	49.3 Å²	49.3	2%	0.022	25%	0.253	C	S	.	.	H	α-helix	trans	-68.3	-36.1	-179.8	69.6	-172.6	-179.6	-170.3	0	113.7	G38 I41 F177 T178 Y179 L185 S309	G38-K181 PolarHBondContact O-NZ 2.61Å; I41-K181 HydrophobicContact CG2-CD 4.22Å; I41-K181 HydrophobicContact CG2-CG 4.27Å; I41-K181 WeakPolarHBondContact O-CD 3.41Å; I41-K181 WeakPolarHBondContact O-CE 3.44Å; I41-K181 PolarHBondContact O-NZ 3.17Å; F177-K181 PolarHBondContact O-N 3.25Å; T178-K181 VanDerWaalsContact O-CG 3.24Å; T178-K181 WeakPolarHBondContact O-CG 3.41Å; Y179-K181 PolarHBondContact O-N 3.18Å; K181-L185 PolarHBondContact O-N 2.91Å; K181-S309 WeakPolarHBondContact CB-OG 3.05Å
182	V	82	Confident	85.9	Confident	58 Å²	58	46.8 Å²	46.8	35%	0.352	24%	0.238	S	C	.	.	H	α-helix	trans	-68.5	-42.8	176.4	175.1	0	0	0	0	109.8	T178 Y179 A184 L185 I186	T178-V182 WeakPolarHBondContact O-CG2 3.35Å; T178-V182 PolarHBondContact O-N 3.2Å; Y179-V182 PolarHBondContact O-N 3.07Å; V182-A184 VanDerWaalsContact C-N 3.35Å; V182-A184 PolarHBondContact O-N 2.9Å; V182-L185 PolarHBondContact O-N 2.85Å; V182-I186 HydrophobicContact CG1-CD1 3.72Å; V182-I186 HydrophobicContact CG1-CG1 4.35Å; V182-I186 VanDerWaalsContact O-CG1 3.29Å; V182-I186 WeakPolarHBondContact O-CG1 3.25Å; V182-I186 PolarHBondContact O-N 3.26Å
183	A	84.8	Confident	86.6	Confident	44 Å²	44	45.7 Å²	45.7	36%	0.364	23%	0.233	S	C	.	.	H	α-helix	trans	-59.8	-43.1	175.8	0	0	0	0	0	112.4	Y179 A180 L185 I186 M187	Y179-A183 WeakPolarHBondContact O-CB 3.33Å; Y179-A183 PolarHBondContact O-N 3.5Å; A180-A183 PolarHBondContact O-N 3.29Å; A183-L185 PolarHBondContact O-N 2.87Å; A183-I186 PolarHBondContact O-N 3.16Å; A183-M187 WeakPolarHBondContact O-CB 3.3Å; A183-M187 PolarHBondContact O-N 3.02Å
184	A	87.8	Confident	87.4	Confident	0 Å²	0	48 Å²	48	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-58.9	-47.2	177.2	0	0	0	0	0	112.5	F46 A180 V182 M187 I188 M302 F305	F46-A184 HydrophobicContact CZ-CB 4.35Å; A180-A184 PolarHBondContact O-N 3.01Å; V182-A184 VanDerWaalsContact C-N 3.35Å; V182-A184 PolarHBondContact O-N 2.9Å; A184-M187 WeakPolarHBondContact O-CB 3.5Å; A184-M187 PolarHBondContact O-N 2.89Å; A184-I188 WeakPolarHBondContact O-CG1 3.49Å; A184-I188 PolarHBondContact O-N 2.84Å; A184-M302 HydrophobicContact CB-SD 4.32Å; A184-F305 HydrophobicContact CB-CB 3.86Å; A184-F305 HydrophobicContact CB-CD2 4.13Å; A184-F305 HydrophobicContact CB-CG 4.48Å
185	L	90.8	Very high	88.1	Confident	3 Å²	3	48 Å²	48	2%	0.016	25%	0.247	C	C	.	.	H	α-helix	trans	-68.2	-40.2	-179.9	-71.9	172.8	0	0	0	112.5	I41 I45 F46 K181 V182 A183 M187 I188 I189 I263 A267	I41-L185 HydrophobicContact CD1-CD1 4.36Å; I41-L185 HydrophobicContact CG2-CD1 3.37Å; I45-L185 HydrophobicContact CG1-CD2 3.95Å; I45-L185 HydrophobicContact CG2-CD1 4.36Å; I45-L185 HydrophobicContact CG2-CD2 3.94Å; F46-L185 HydrophobicContact CE1-CD2 4.34Å; F46-L185 HydrophobicContact CZ-CD2 4.14Å; F46-L185 HydrophobicContact CZ-CG 4.36Å; K181-L185 PolarHBondContact O-N 2.91Å; V182-L185 PolarHBondContact O-N 2.85Å; A183-L185 PolarHBondContact O-N 2.87Å; L185-M187 VanDerWaalsContact C-N 3.27Å; L185-M187 PolarHBondContact O-N 3.23Å; L185-I188 PolarHBondContact O-N 3.33Å; L185-I189 WeakPolarHBondContact O-CB 3.28Å; L185-I189 VanDerWaalsContact O-CG1 3.26Å; L185-I189 WeakPolarHBondContact O-CG1 3.48Å; L185-I189 PolarHBondContact O-N 2.55Å; L185-I263 HydrophobicContact CB-CG2 4.3Å; L185-I263 HydrophobicContact CD1-CG2 3.91Å; L185-A267 HydrophobicContact CD2-CB 4.28Å
186	I	90.4	Very high	88.9	Confident	88 Å²	88	47.2 Å²	47.2	45%	0.451	24%	0.242	S	C	.	.	H	α-helix	trans	-58.7	-44.2	173.8	-71.1	171.1	0	0	0	110	V182 A183 I188 I189 I190	V182-I186 HydrophobicContact CG1-CD1 3.72Å; V182-I186 HydrophobicContact CG1-CG1 4.35Å; V182-I186 VanDerWaalsContact O-CG1 3.29Å; V182-I186 WeakPolarHBondContact O-CG1 3.25Å; V182-I186 PolarHBondContact O-N 3.26Å; A183-I186 PolarHBondContact O-N 3.16Å; I186-I188 PolarHBondContact O-N 3.12Å; I186-I189 PolarHBondContact O-N 3.44Å; I186-I190 HydrophobicContact CG2-CD1 3.52Å; I186-I190 HydrophobicContact CG2-CG1 4.21Å; I186-I190 WeakPolarHBondContact O-CB 3.45Å; I186-I190 VanDerWaalsContact O-CG1 3.29Å; I186-I190 WeakPolarHBondContact O-CG1 3.11Å; I186-I190 PolarHBondContact O-N 2.82Å
187	M	91.3	Very high	89.5	Confident	57 Å²	57	46.8 Å²	46.8	28%	0.281	26%	0.256	S	S	.	.	H	α-helix	trans	-60.6	-46.6	178.9	-163.9	-165.3	-74.4	0	0	111.9	A183 A184 L185 T191 Y295 I301 M302 F305	A183-M187 WeakPolarHBondContact O-CB 3.3Å; A183-M187 PolarHBondContact O-N 3.02Å; A184-M187 WeakPolarHBondContact O-CB 3.5Å; A184-M187 PolarHBondContact O-N 2.89Å; L185-M187 VanDerWaalsContact C-N 3.27Å; L185-M187 PolarHBondContact O-N 3.23Å; M187-T191 VanDerWaalsContact O-CB 3.27Å; M187-T191 WeakPolarHBondContact O-CB 3.28Å; M187-T191 PolarHBondContact O-N 3.32Å; M187-T191 PolarHBondContact O-OG1 3.32Å; M187-Y295 HydrophobicContact CG-CE2 4.3Å; M187-Y295 VanDerWaalsContact CG-OH 3.28Å; M187-Y295 WeakPolarHBondContact CG-OH 3.48Å; M187-Y295 PolarHBondContact O-OH 3.5Å; M187-Y295 HydrophobicContact SD-CD2 4.32Å; M187-Y295 HydrophobicContact SD-CE1 4.42Å; M187-Y295 HydrophobicContact SD-CE2 3.52Å; M187-Y295 VanDerWaalsContact SD-CE2 3.52Å; M187-I301 HydrophobicContact CE-CG2 4.36Å; M187-M302 HydrophobicContact SD-CE 3.93Å; M187-F305 HydrophobicContact CE-CD2 4.39Å; M187-F305 HydrophobicContact CE-CE2 3.83Å
188	I	93.6	Very high	90	Very high	0 Å²	0	52.8 Å²	52.8	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-60.6	-48.9	176.9	-68.8	165.6	0	0	0	110.6	F46 A184 L185 I186 T191 G192 A267 A270 Y271 A287 F290 M302	F46-I188 HydrophobicContact CE1-CD1 4.07Å; A184-I188 WeakPolarHBondContact O-CG1 3.49Å; A184-I188 PolarHBondContact O-N 2.84Å; L185-I188 PolarHBondContact O-N 3.33Å; I186-I188 PolarHBondContact O-N 3.12Å; I188-T191 PolarHBondContact O-N 3.41Å; I188-G192 PolarHBondContact O-N 3.46Å; I188-A267 HydrophobicContact CG2-CB 4.37Å; I188-A270 HydrophobicContact CG2-CB 3.79Å; I188-A270 WeakPolarHBondContact O-CB 3.49Å; I188-Y271 HydrophobicContact CD1-CE1 3.98Å; I188-Y271 HydrophobicContact CG1-CE1 4.48Å; I188-Y271 HydrophobicContact CG2-CD1 4.28Å; I188-Y271 HydrophobicContact CG2-CE1 3.93Å; I188-A287 HydrophobicContact CD1-CB 4.41Å; I188-F290 HydrophobicContact CG1-CD1 4.39Å; I188-F290 HydrophobicContact CG1-CE1 4.22Å; I188-F290 HydrophobicContact CG2-CE1 4.47Å; I188-F290 HydrophobicContact CG2-CZ 4.33Å; I188-M302 HydrophobicContact CD1-CE 4.1Å; I188-M302 HydrophobicContact CD1-SD 4.01Å; I188-M302 HydrophobicContact CG1-CE 3.67Å; I188-M302 HydrophobicContact CG1-SD 4.26Å
189	I	94.9	Very high	90.7	Very high	23 Å²	23	53.6 Å²	53.6	12%	0.118	30%	0.297	C	S	.	.	H	α-helix	trans	-64.3	-48.3	-176.8	-69.4	168.3	0	0	0	111.3	L185 I186 T191 G192 F193 I263 M266 A267	L185-I189 WeakPolarHBondContact O-CB 3.28Å; L185-I189 VanDerWaalsContact O-CG1 3.26Å; L185-I189 WeakPolarHBondContact O-CG1 3.48Å; L185-I189 PolarHBondContact O-N 2.55Å; I186-I189 PolarHBondContact O-N 3.44Å; I189-T191 VanDerWaalsContact C-N 3.28Å; I189-T191 PolarHBondContact O-N 3.04Å; I189-G192 PolarHBondContact O-N 3.46Å; I189-F193 HydrophobicContact CG2-CD2 3.79Å; I189-F193 HydrophobicContact CG2-CE2 3.54Å; I189-F193 VanDerWaalsContact O-CD2 3.27Å; I189-F193 WeakPolarHBondContact O-CD2 3.36Å; I189-F193 PolarHBondContact O-N 3.42Å; I189-I263 HydrophobicContact CD1-CB 4.36Å; I189-I263 HydrophobicContact CD1-CG1 4.49Å; I189-I263 HydrophobicContact CD1-CG2 3.94Å; I189-M266 HydrophobicContact CD1-CB 4.2Å; I189-M266 HydrophobicContact CG1-CB 4.07Å; I189-M266 HydrophobicContact CG2-CB 4.21Å; I189-A267 HydrophobicContact CG1-CB 4.34Å
190	I	95.4	Very high	91.2	Very high	98 Å²	98	50.1 Å²	50.1	50%	0.503	29%	0.286	S	S	.	.	H	α-helix	trans	-58.7	-45.3	177.7	-70.1	173.5	0	0	0	110	I186 G192 F193 V194	I186-I190 HydrophobicContact CG2-CD1 3.52Å; I186-I190 HydrophobicContact CG2-CG1 4.21Å; I186-I190 WeakPolarHBondContact O-CB 3.45Å; I186-I190 VanDerWaalsContact O-CG1 3.29Å; I186-I190 WeakPolarHBondContact O-CG1 3.11Å; I186-I190 PolarHBondContact O-N 2.82Å; I190-G192 VanDerWaalsContact C-N 3.32Å; I190-G192 PolarHBondContact O-N 2.89Å; I190-F193 PolarHBondContact O-N 3.47Å; I190-V194 HydrophobicContact CG2-CG2 4.49Å; I190-V194 WeakPolarHBondContact O-CG2 3.26Å; I190-V194 PolarHBondContact O-N 2.94Å
191	T	94.3	Very high	91.6	Very high	17 Å²	17	52.2 Å²	52.2	10%	0.104	30%	0.297	C	S	.	.	H	α-helix	trans	-61.7	-41.5	179	-58	0	0	0	0	111.6	M187 I188 I189 F193 V194 Q195 F290 I294 Y295	M187-T191 VanDerWaalsContact O-CB 3.27Å; M187-T191 WeakPolarHBondContact O-CB 3.28Å; M187-T191 PolarHBondContact O-N 3.32Å; M187-T191 PolarHBondContact O-OG1 3.32Å; I188-T191 PolarHBondContact O-N 3.41Å; I189-T191 VanDerWaalsContact C-N 3.28Å; I189-T191 PolarHBondContact O-N 3.04Å; T191-F193 PolarHBondContact O-N 2.99Å; T191-V194 PolarHBondContact O-N 3.32Å; T191-Q195 WeakPolarHBondContact O-CG 3.48Å; T191-Q195 PolarHBondContact O-N 2.76Å; T191-F290 HydrophobicContact CG2-CE1 3.91Å; T191-F290 HydrophobicContact CG2-CZ 3.52Å; T191-I294 HydrophobicContact CG2-CB 4.37Å; T191-I294 HydrophobicContact CG2-CG1 4.26Å; T191-I294 HydrophobicContact CG2-CG2 3.65Å; T191-Y295 HydrophobicContact CG2-CE1 4.31Å; T191-Y295 PolarHBondContact OG1-OH 3.28Å
192	G	94.6	Very high	91.8	Very high	1 Å²	1	57.6 Å²	57.6	1%	0.01	33%	0.326	C	S	.	.	H	α-helix	trans	-58.3	-46	173.2	0	0	0	0	0	112.7	I188 I189 I190 V194 Q195 I196	I188-G192 PolarHBondContact O-N 3.46Å; I189-G192 PolarHBondContact O-N 3.46Å; I190-G192 VanDerWaalsContact C-N 3.32Å; I190-G192 PolarHBondContact O-N 2.89Å; G192-V194 VanDerWaalsContact C-N 3.33Å; G192-V194 PolarHBondContact O-N 3.24Å; G192-Q195 PolarHBondContact O-N 3.48Å; G192-I196 VanDerWaalsContact O-CG1 3.32Å; G192-I196 WeakPolarHBondContact O-CG1 3.38Å; G192-I196 PolarHBondContact O-N 3.15Å
193	F	95.8	Very high	91.8	Very high	110 Å²	110	55.7 Å²	55.7	48%	0.482	32%	0.318	S	S	.	.	H	α-helix	trans	-61.1	-40.5	175.4	-80.1	-65.2	0	0	0	112.7	I189 I190 T191 I196 G197 M266	I189-F193 HydrophobicContact CG2-CD2 3.79Å; I189-F193 HydrophobicContact CG2-CE2 3.54Å; I189-F193 VanDerWaalsContact O-CD2 3.27Å; I189-F193 WeakPolarHBondContact O-CD2 3.36Å; I189-F193 PolarHBondContact O-N 3.42Å; I190-F193 PolarHBondContact O-N 3.47Å; T191-F193 PolarHBondContact O-N 2.99Å; F193-I196 PolarHBondContact O-N 3.29Å; F193-G197 PolarHBondContact O-N 3.49Å; F193-M266 HydrophobicContact CZ-SD 3.97Å
194	V	96.2	Very high	91.8	Very high	71 Å²	71	56.3 Å²	56.3	43%	0.43	32%	0.315	S	S	.	.	H	α-helix	trans	-62.4	-43.7	175.1	175.1	0	0	0	0	111.3	I190 T191 G192 G197 F198	I190-V194 HydrophobicContact CG2-CG2 4.49Å; I190-V194 WeakPolarHBondContact O-CG2 3.26Å; I190-V194 PolarHBondContact O-N 2.94Å; T191-V194 PolarHBondContact O-N 3.32Å; G192-V194 VanDerWaalsContact C-N 3.33Å; G192-V194 PolarHBondContact O-N 3.24Å; V194-G197 CarbonylContact O-C 3.49Å; V194-G197 WeakPolarHBondContact O-CA 3.41Å; V194-G197 PolarHBondContact O-N 2.98Å; V194-G197 VanDerWaalsContact O-N 3.11Å; V194-F198 HydrophobicContact CG1-CD2 3.99Å; V194-F198 HydrophobicContact CG1-CE2 3.43Å; V194-F198 VanDerWaalsContact CG1-CE2 3.43Å; V194-F198 HydrophobicContact CG1-CZ 4.02Å; V194-F198 WeakPolarHBondContact O-CD2 3.38Å; V194-F198 PolarHBondContact O-N 2.87Å
195	Q	95.2	Very high	91.8	Very high	31 Å²	31	61.6 Å²	61.6	15%	0.145	35%	0.347	C	S	.	.	H	α-helix	trans	-63.9	-40.7	177.9	-71.3	-63.1	-35.8	0	0	112.6	T191 G192 G197 F198 G199 K200 V274 I294	T191-Q195 WeakPolarHBondContact O-CG 3.48Å; T191-Q195 PolarHBondContact O-N 2.76Å; G192-Q195 PolarHBondContact O-N 3.48Å; Q195-G197 VanDerWaalsContact C-N 3.28Å; Q195-G197 PolarHBondContact O-N 3.43Å; Q195-F198 CarbonylContact O-C 3.55Å; Q195-F198 WeakPolarHBondContact O-CA 3.22Å; Q195-F198 PolarHBondContact O-N 3.27Å; Q195-G199 PolarHBondContact O-N 3.46Å; Q195-K200 HydrophobicContact CB-CB 4.3Å; Q195-K200 WeakPolarHBondContact O-CB 3.48Å; Q195-K200 PolarHBondContact O-N 3.12Å; Q195-V274 HydrophobicContact CG-CG2 3.82Å; Q195-I294 HydrophobicContact CG-CD1 4.32Å
196	I	94.2	Very high	91.6	Very high	63 Å²	63	63.1 Å²	63.1	32%	0.323	36%	0.363	S	S	.	.	H	α-helix	trans	-61.4	-40.3	172	-66.5	166.8	0	0	0	110.5	G192 F193 F198 G199 V201 V269 T273	G192-I196 VanDerWaalsContact O-CG1 3.32Å; G192-I196 WeakPolarHBondContact O-CG1 3.38Å; G192-I196 PolarHBondContact O-N 3.15Å; F193-I196 PolarHBondContact O-N 3.29Å; I196-F198 PolarHBondContact O-N 2.9Å; I196-G199 WeakPolarHBondContact O-CA 3.1Å; I196-G199 PolarHBondContact O-N 3.47Å; I196-V201 HydrophobicContact CG1-CG1 4.39Å; I196-V201 HydrophobicContact CG2-CG1 4.24Å; I196-V269 HydrophobicContact CD1-CG1 4.09Å; I196-T273 HydrophobicContact CD1-CG2 4.09Å; I196-T273 HydrophobicContact CG1-CG2 3.6Å
197	G	93.9	Very high	91.7	Very high	66 Å²	66	59.9 Å²	59.9	68%	0.68	35%	0.35	S	S	*	.	H	α-helix	trans	-60.1	-29.1	173.6	0	0	0	0	0	113.7	F193 V194 Q195 G199	F193-G197 PolarHBondContact O-N 3.49Å; V194-G197 CarbonylContact O-C 3.49Å; V194-G197 WeakPolarHBondContact O-CA 3.41Å; V194-G197 PolarHBondContact O-N 2.98Å; V194-G197 VanDerWaalsContact O-N 3.11Å; Q195-G197 VanDerWaalsContact C-N 3.28Å; Q195-G197 PolarHBondContact O-N 3.43Å; G197-G199 VanDerWaalsContact C-N 3.27Å
198	F	94.3	Very high	91.8	Very high	152 Å²	152	62.6 Å²	62.6	67%	0.667	36%	0.36	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.6	5	171	-64.4	-45.5	0	0	0	114.1	V194 Q195 I196	V194-F198 HydrophobicContact CG1-CD2 3.99Å; V194-F198 HydrophobicContact CG1-CE2 3.43Å; V194-F198 VanDerWaalsContact CG1-CE2 3.43Å; V194-F198 HydrophobicContact CG1-CZ 4.02Å; V194-F198 WeakPolarHBondContact O-CD2 3.38Å; V194-F198 PolarHBondContact O-N 2.87Å; Q195-F198 CarbonylContact O-C 3.55Å; Q195-F198 WeakPolarHBondContact O-CA 3.22Å; Q195-F198 PolarHBondContact O-N 3.27Å; I196-F198 PolarHBondContact O-N 2.9Å
199	G	91.9	Very high	91.7	Very high	47 Å²	47	67.7 Å²	67.7	49%	0.485	39%	0.388	S	S	.	.	T	Hydrogen-bonded Turn	trans	78.8	13.1	179.4	0	0	0	0	0	114.6	Q195 I196 G197 V201	Q195-G199 PolarHBondContact O-N 3.46Å; I196-G199 WeakPolarHBondContact O-CA 3.1Å; I196-G199 PolarHBondContact O-N 3.47Å; G197-G199 VanDerWaalsContact C-N 3.27Å; G199-V201 VanDerWaalsContact C-N 3.28Å; G199-V201 PolarHBondContact O-N 3.48Å
200	K	91	Very high	91.4	Very high	107 Å²	107	72.9 Å²	72.9	47%	0.465	42%	0.415	S	S	.	.			trans	-78.8	75.3	178.9	-65.3	-67.3	-174.3	179.8	0	111.5	Q195 T273	Q195-K200 HydrophobicContact CB-CB 4.3Å; Q195-K200 WeakPolarHBondContact O-CB 3.48Å; Q195-K200 PolarHBondContact O-N 3.12Å; K200-T273 WeakPolarHBondContact O-CB 3.48Å
201	V	90	Very high	91.3	Very high	56 Å²	56	69.5 Å²	69.5	34%	0.339	40%	0.401	S	S	.	.			trans	-117.8	10.3	-179.6	-63.1	0	0	0	0	113.3	I196 G199 G203 L204	I196-V201 HydrophobicContact CG1-CG1 4.39Å; I196-V201 HydrophobicContact CG2-CG1 4.24Å; G199-V201 VanDerWaalsContact C-N 3.28Å; G199-V201 PolarHBondContact O-N 3.48Å; V201-G203 PolarHBondContact O-N 2.76Å; V201-L204 HydrophobicContact CB-CD1 4.38Å; V201-L204 HydrophobicContact CG1-CD1 4.44Å; V201-L204 WeakPolarHBondContact O-CB 3.27Å; V201-L204 PolarHBondContact O-N 2.7Å
202	D	86.2	Confident	91.3	Very high	117 Å²	117	71.9 Å²	71.9	63%	0.626	41%	0.413	S	S	*	.	G	3₁₀ helix	trans	-57.2	-37.6	-175.9	-58.4	-39.5	0	0	0	112.3	L204 V205	D202-L204 PolarHBondContact O-N 2.64Å; D202-L204 VanDerWaalsContact O-N 3.15Å; D202-V205 WeakPolarHBondContact O-CB 3.41Å; D202-V205 PolarHBondContact O-N 2.85Å; D202-V205 VanDerWaalsContact O-N 3.08Å
203	G	80.7	Confident	91.3	Very high	18 Å²	18	77.6 Å²	77.6	19%	0.186	43%	0.434	C	S	.	.	G	3₁₀ helix	trans	-65.5	-12.4	175.8	0	0	0	0	0	114.6	I59 V201	I59-G203 WeakPolarHBondContact CD1-O 3.14Å; V201-G203 PolarHBondContact O-N 2.76Å
204	L	84.8	Confident	91.3	Very high	57 Å²	57	74.5 Å²	74.5	30%	0.298	43%	0.426	S	S	.	.	G	3₁₀ helix	trans	-97.6	-10.2	175.8	-62.1	169.4	0	0	0	112.4	I59 V201 D202 A207 V272	I59-L204 HydrophobicContact CG2-CD2 4.37Å; V201-L204 HydrophobicContact CB-CD1 4.38Å; V201-L204 HydrophobicContact CG1-CD1 4.44Å; V201-L204 WeakPolarHBondContact O-CB 3.27Å; V201-L204 PolarHBondContact O-N 2.7Å; D202-L204 PolarHBondContact O-N 2.64Å; D202-L204 VanDerWaalsContact O-N 3.15Å; L204-A207 WeakPolarHBondContact O-CB 3.44Å; L204-A207 PolarHBondContact O-N 2.96Å; L204-V272 HydrophobicContact CD2-CG2 3.67Å; L204-V272 HydrophobicContact CG-CG2 4.15Å
205	V	87.6	Confident	91.2	Very high	112 Å²	112	73.7 Å²	73.7	68%	0.679	42%	0.422	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.7	131.9	174.6	-177.7	0	0	0	0	108.6	D202 A207	D202-V205 WeakPolarHBondContact O-CB 3.41Å; D202-V205 PolarHBondContact O-N 2.85Å; D202-V205 VanDerWaalsContact O-N 3.08Å; V205-A207 PolarHBondContact O-N 2.86Å
206	G	88.5	Confident	91	Very high	35 Å²	35	72.8 Å²	72.8	36%	0.361	42%	0.422	S	S	.	.	T	Hydrogen-bonded Turn	trans	63.7	29	-174.9	0	0	0	0	0	112.6	F208 D209	G206-F208 PolarHBondContact O-N 3.11Å; G206-D209 WeakPolarHBondContact CA-OD2 3.48Å; G206-D209 VanDerWaalsContact O-CB 3.28Å; G206-D209 WeakPolarHBondContact O-CB 3.33Å; G206-D209 PolarHBondContact O-N 3.4Å
207	A	90.6	Very high	91	Very high	20 Å²	20	70.1 Å²	70.1	17%	0.165	41%	0.409	C	S	.	.	T	Hydrogen-bonded Turn	trans	-53	-28.4	-171.9	0	0	0	0	0	113.9	S58 I59 G60 L204 V205	S58-A207 PolarHBondContact OG-O 3.33Å; I59-A207 PolarHBondContact N-O 3.45Å; G60-A207 PolarHBondContact N-O 2.76Å; L204-A207 WeakPolarHBondContact O-CB 3.44Å; L204-A207 PolarHBondContact O-N 2.96Å; V205-A207 PolarHBondContact O-N 2.86Å
208	F	94.2	Very high	91	Very high	113 Å²	113	68.4 Å²	68.4	50%	0.496	38%	0.384	S	S	.	.	T	Hydrogen-bonded Turn	trans	-93.8	0.3	-179.3	-66.7	-77.4	0	0	0	114.7	S58 I64 G206 N210 S211	S58-F208 WeakPolarHBondContact OG-CA 3.45Å; I64-F208 HydrophobicContact CD1-CE1 3.62Å; I64-F208 HydrophobicContact CD1-CZ 4.04Å; I64-F208 HydrophobicContact CG1-CE1 4.44Å; G206-F208 PolarHBondContact O-N 3.11Å; F208-N210 PolarHBondContact O-N 3.29Å; F208-S211 WeakPolarHBondContact O-CB 3.11Å; F208-S211 PolarHBondContact O-N 2.91Å; F208-S211 PolarHBondContact O-OG 2.94Å
209	D	90.9	Very high	91	Very high	108 Å²	108	61.2 Å²	61.2	58%	0.578	35%	0.352	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62	138.5	-178.9	-65.1	-8.4	0	0	0	110.2	G206 S211	G206-D209 WeakPolarHBondContact CA-OD2 3.48Å; G206-D209 VanDerWaalsContact O-CB 3.28Å; G206-D209 WeakPolarHBondContact O-CB 3.33Å; G206-D209 PolarHBondContact O-N 3.4Å; D209-S211 PolarHBondContact O-N 3.29Å
210	N	89.2	Confident	91.1	Very high	131 Å²	131	62.1 Å²	62.1	70%	0.701	34%	0.343	S	S	*	.	T	Hydrogen-bonded Turn	trans	60.3	18.6	-178.3	-51.1	-51.1	0	0	0	116.3	F208 D212	F208-N210 PolarHBondContact O-N 3.29Å; N210-D212 PolarHBondContact O-N 3.3Å
211	S	94.1	Very high	91.3	Very high	28 Å²	28	57 Å²	57	20%	0.196	32%	0.321	C	S	.	.			trans	-57	123.7	178.4	-59.5	0	0	0	0	112.5	V56 S58 F208 D209	V56-S211 WeakPolarHBondContact O-CA 3.3Å; S58-S211 WeakPolarHBondContact CB-OG 3.46Å; S58-S211 PolarHBondContact OG-OG 2.94Å; F208-S211 WeakPolarHBondContact O-CB 3.11Å; F208-S211 PolarHBondContact O-N 2.91Å; F208-S211 PolarHBondContact O-OG 2.94Å; D209-S211 PolarHBondContact O-N 3.29Å
212	D	93.7	Very high	91.5	Very high	67 Å²	67	55.4 Å²	55.4	36%	0.358	31%	0.309	S	S	.	.			trans	-90.6	109.2	168.1	-171.5	-6.7	0	0	0	110.1	V56 N210 S214 A217	V56-D212 PolarHBondContact O-N 3.35Å; N210-D212 PolarHBondContact O-N 3.3Å; D212-S214 WeakPolarHBondContact OD1-CA 3.48Å; D212-S214 WeakPolarHBondContact OD1-CB 3.5Å; D212-S214 PolarHBondContact OD1-N 2.83Å; D212-S214 PolarHBondContact OD1-OG 3.08Å; D212-S214 PolarHBondContact OD2-OG 3.09Å; D212-A217 HydrophobicContact CB-CB 4.26Å
213	W	94.9	Very high	91.9	Very high	120 Å²	120	49.9 Å²	49.9	46%	0.455	28%	0.28	S	S	.	.			trans	-101.6	16	176.2	-64.9	98.5	0	0	0	112.7	A61 I64 I218	A61-W213 HydrophobicContact CB-CH2 3.99Å; A61-W213 HydrophobicContact CB-CZ2 3.73Å; I64-W213 HydrophobicContact CB-CH2 4.37Å; I64-W213 HydrophobicContact CD1-CH2 3.93Å; I64-W213 HydrophobicContact CD1-CZ2 4.42Å; I64-W213 HydrophobicContact CG2-CH2 4.23Å; W213-I218 HydrophobicContact CB-CD1 4.43Å; W213-I218 HydrophobicContact CE3-CD1 3.96Å; W213-I218 HydrophobicContact CE3-CG1 4.41Å; W213-I218 VanDerWaalsContact O-CD1 3.28Å; W213-I218 WeakPolarHBondContact O-CD1 3.38Å
214	S	94.9	Very high	92.5	Very high	46 Å²	46	49.1 Å²	49.1	32%	0.322	27%	0.271	S	S	.	.			trans	-60.6	139.6	175.6	69.2	0	0	0	0	109.9	D212 G216 A217 I218	D212-S214 WeakPolarHBondContact OD1-CA 3.48Å; D212-S214 WeakPolarHBondContact OD1-CB 3.5Å; D212-S214 PolarHBondContact OD1-N 2.83Å; D212-S214 PolarHBondContact OD1-OG 3.08Å; D212-S214 PolarHBondContact OD2-OG 3.09Å; S214-G216 PolarHBondContact O-N 3.39Å; S214-G216 VanDerWaalsContact O-N 3.08Å; S214-A217 PolarHBondContact O-N 3.01Å; S214-A217 VanDerWaalsContact O-N 3.09Å; S214-A217 WeakPolarHBondContact OG-CB 3.36Å; S214-A217 PolarHBondContact OG-N 3.29Å; S214-I218 WeakPolarHBondContact O-CG1 3.45Å; S214-I218 PolarHBondContact O-N 3.09Å
215	P	93.8	Very high	93	Very high	53 Å²	53	46.4 Å²	46.4	34%	0.344	26%	0.257	S	S	.	.	H	α-helix	trans	-54.8	-32.4	-178.2	-30.7	36.8	0	0	0	114	T219 F420 F424	P215-T219 WeakPolarHBondContact O-CB 3.26Å; P215-T219 PolarHBondContact O-N 3.31Å; P215-T219 PolarHBondContact O-OG1 3.46Å; P215-F420 HydrophobicContact CB-CE2 4.29Å; P215-F420 HydrophobicContact CB-CZ 3.89Å; P215-F424 HydrophobicContact CB-CB 4.42Å; P215-F424 HydrophobicContact CB-CD1 3.34Å; P215-F424 HydrophobicContact CB-CD2 3.88Å; P215-F424 HydrophobicContact CB-CE1 3.35Å; P215-F424 HydrophobicContact CB-CE2 3.9Å; P215-F424 HydrophobicContact CB-CG 3.61Å; P215-F424 HydrophobicContact CB-CZ 3.63Å; P215-F424 HydrophobicContact CG-CD1 4.36Å; P215-F424 HydrophobicContact CG-CE1 3.9Å; P215-F424 HydrophobicContact CG-CZ 4.01Å
216	G	91.9	Very high	93.4	Very high	13 Å²	13	41 Å²	41	13%	0.134	23%	0.225	C	C	.	.	H	α-helix	trans	-71	-44	177	0	0	0	0	0	113.5	S214 T219 K220 A428	S214-G216 PolarHBondContact O-N 3.39Å; S214-G216 VanDerWaalsContact O-N 3.08Å; G216-T219 PolarHBondContact O-N 3.06Å; G216-K220 PolarHBondContact O-N 3.3Å; G216-K220 VanDerWaalsContact O-N 3.09Å; G216-A428 WeakPolarHBondContact O-CB 3.44Å
217	A	92.9	Very high	93.5	Very high	6 Å²	6	40.2 Å²	40.2	5%	0.05	21%	0.211	C	C	.	.	H	α-helix	trans	-60	-49.3	174	0	0	0	0	0	111.5	N55 D212 S214 T219 K220 A221	N55-A217 VanDerWaalsContact O-CB 3.29Å; N55-A217 WeakPolarHBondContact O-CB 3.37Å; D212-A217 HydrophobicContact CB-CB 4.26Å; S214-A217 PolarHBondContact O-N 3.01Å; S214-A217 VanDerWaalsContact O-N 3.09Å; S214-A217 WeakPolarHBondContact OG-CB 3.36Å; S214-A217 PolarHBondContact OG-N 3.29Å; A217-T219 VanDerWaalsContact C-N 3.26Å; A217-T219 PolarHBondContact O-N 3.31Å; A217-K220 PolarHBondContact O-N 3.26Å; A217-A221 WeakPolarHBondContact O-CB 3.16Å; A217-A221 PolarHBondContact O-N 2.73Å
218	I	95.6	Very high	93.7	Very high	31 Å²	31	39.4 Å²	39.4	16%	0.159	20%	0.204	C	C	.	.	H	α-helix	trans	-57.1	-42.8	177.2	-65.4	171.7	0	0	0	110.5	I65 W213 S214 A221 F222	I65-I218 HydrophobicContact CD1-CG2 4.15Å; W213-I218 HydrophobicContact CB-CD1 4.43Å; W213-I218 HydrophobicContact CE3-CD1 3.96Å; W213-I218 HydrophobicContact CE3-CG1 4.41Å; W213-I218 VanDerWaalsContact O-CD1 3.28Å; W213-I218 WeakPolarHBondContact O-CD1 3.38Å; S214-I218 WeakPolarHBondContact O-CG1 3.45Å; S214-I218 PolarHBondContact O-N 3.09Å; I218-A221 PolarHBondContact O-N 3.41Å; I218-F222 HydrophobicContact CG2-CD2 4Å; I218-F222 HydrophobicContact CG2-CE2 4.45Å; I218-F222 WeakPolarHBondContact O-CB 3.2Å; I218-F222 PolarHBondContact O-N 2.7Å
219	T	94.5	Very high	93.6	Very high	1 Å²	1	34 Å²	34	1%	0.006	18%	0.181	C	C	.	.	H	α-helix	trans	-63.8	-47.9	-179.3	-63.2	0	0	0	0	112.2	P215 G216 A217 A221 F222 Y223 L421 F424 A425	P215-T219 WeakPolarHBondContact O-CB 3.26Å; P215-T219 PolarHBondContact O-N 3.31Å; P215-T219 PolarHBondContact O-OG1 3.46Å; G216-T219 PolarHBondContact O-N 3.06Å; A217-T219 VanDerWaalsContact C-N 3.26Å; A217-T219 PolarHBondContact O-N 3.31Å; T219-A221 PolarHBondContact O-N 3Å; T219-F222 PolarHBondContact O-N 3.25Å; T219-Y223 HydrophobicContact CG2-CD2 4.4Å; T219-Y223 HydrophobicContact CG2-CE2 3.98Å; T219-Y223 PolarHBondContact O-N 3.49Å; T219-L421 HydrophobicContact CG2-CB 4.4Å; T219-L421 HydrophobicContact CG2-CD2 4.07Å; T219-L421 VanDerWaalsContact CG2-O 3.25Å; T219-L421 WeakPolarHBondContact CG2-O 3.15Å; T219-F424 HydrophobicContact CG2-CB 4.49Å; T219-F424 VanDerWaalsContact OG1-CB 3.25Å; T219-F424 WeakPolarHBondContact OG1-CB 3.37Å; T219-A425 HydrophobicContact CG2-CB 4.11Å
220	K	92.5	Very high	93.5	Very high	65 Å²	65	29.7 Å²	29.7	28%	0.283	16%	0.159	S	C	.	.	H	α-helix	trans	-61.8	-44.6	176.7	-73	-171.6	-71.6	155.6	0	111.3	N55 G216 A217 F222 Y223 V224 A428	N55-K220 HydrophobicContact CB-CB 4.37Å; N55-K220 WeakPolarHBondContact OD1-CB 3.03Å; N55-K220 WeakPolarHBondContact OD1-CD 3.43Å; N55-K220 WeakPolarHBondContact OD1-CE 3.2Å; N55-K220 PolarHBondContact OD1-NZ 3.07Å; G216-K220 PolarHBondContact O-N 3.3Å; G216-K220 VanDerWaalsContact O-N 3.09Å; A217-K220 PolarHBondContact O-N 3.26Å; K220-F222 VanDerWaalsContact C-N 3.33Å; K220-F222 PolarHBondContact O-N 3.16Å; K220-Y223 PolarHBondContact O-N 3.3Å; K220-V224 WeakPolarHBondContact O-CG2 3.09Å; K220-V224 PolarHBondContact O-N 2.8Å; K220-V224 VanDerWaalsContact O-N 3.09Å; K220-A428 HydrophobicContact CD-CB 4.25Å; K220-A428 HydrophobicContact CG-CB 4.03Å
221	A	95.3	Very high	93.2	Very high	0 Å²	0	23.5 Å²	23.5	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-60.4	-41.6	175.4	0	0	0	0	0	112.1	I52 N55 V56 I65 A217 I218 T219 Y223 V224 G225	I52-A221 HydrophobicContact CG2-CB 4.33Å; N55-A221 HydrophobicContact CB-CB 3.96Å; V56-A221 HydrophobicContact CG1-CB 3.77Å; I65-A221 HydrophobicContact CD1-CB 4.44Å; I65-A221 HydrophobicContact CG1-CB 4.27Å; I65-A221 HydrophobicContact CG2-CB 4.2Å; A217-A221 WeakPolarHBondContact O-CB 3.16Å; A217-A221 PolarHBondContact O-N 2.73Å; I218-A221 PolarHBondContact O-N 3.41Å; T219-A221 PolarHBondContact O-N 3Å; A221-Y223 PolarHBondContact O-N 3.35Å; A221-V224 PolarHBondContact O-N 2.87Å; A221-G225 PolarHBondContact O-N 3.18Å
222	F	95.6	Very high	92.9	Very high	22 Å²	22	22.2 Å²	22.2	10%	0.096	12%	0.117	C	C	.	.	H	α-helix	trans	-62.1	-42.5	175.7	-114.7	-96.5	0	0	0	112	I65 A68 F72 I218 T219 K220 V224 G225 L226 L421	I65-F222 HydrophobicContact CD1-CD2 3.8Å; I65-F222 HydrophobicContact CD1-CE2 3.94Å; I65-F222 HydrophobicContact CG2-CD2 4.42Å; A68-F222 HydrophobicContact CB-CE2 3.92Å; A68-F222 HydrophobicContact CB-CZ 3.59Å; F72-F222 HydrophobicContact CB-CE1 4.25Å; F72-F222 HydrophobicContact CG-CE1 4.44Å; I218-F222 HydrophobicContact CG2-CD2 4Å; I218-F222 HydrophobicContact CG2-CE2 4.45Å; I218-F222 WeakPolarHBondContact O-CB 3.2Å; I218-F222 PolarHBondContact O-N 2.7Å; T219-F222 PolarHBondContact O-N 3.25Å; K220-F222 VanDerWaalsContact C-N 3.33Å; K220-F222 PolarHBondContact O-N 3.16Å; F222-V224 VanDerWaalsContact C-N 3.35Å; F222-V224 PolarHBondContact O-N 3.44Å; F222-G225 PolarHBondContact O-N 2.95Å; F222-L226 HydrophobicContact CD1-CD1 3.84Å; F222-L226 HydrophobicContact CD1-CG 3.99Å; F222-L226 WeakPolarHBondContact O-CB 3.49Å; F222-L226 WeakPolarHBondContact O-CG 3.4Å; F222-L226 PolarHBondContact O-N 3.34Å; F222-L421 HydrophobicContact CB-CD1 4.5Å; F222-L421 HydrophobicContact CB-CD2 3.61Å; F222-L421 HydrophobicContact CD1-CD1 4.11Å; F222-L421 HydrophobicContact CD1-CD2 4.27Å; F222-L421 HydrophobicContact CG-CD2 3.95Å
223	Y	93.9	Very high	92.5	Very high	2 Å²	2	19.2 Å²	19.2	1%	0.008	10%	0.101	C	C	.	.	H	α-helix	trans	-64.1	-41	176.8	-71.5	-21.5	0	0	0	112.5	T219 K220 A221 F227 T373 F377 W380 L421 A425	T219-Y223 HydrophobicContact CG2-CD2 4.4Å; T219-Y223 HydrophobicContact CG2-CE2 3.98Å; T219-Y223 PolarHBondContact O-N 3.49Å; K220-Y223 PolarHBondContact O-N 3.3Å; A221-Y223 PolarHBondContact O-N 3.35Å; Y223-F227 WeakPolarHBondContact O-CB 3.22Å; Y223-F227 PolarHBondContact O-N 2.98Å; Y223-T373 HydrophobicContact CD2-CG2 4.25Å; Y223-F377 HydrophobicContact CE2-CB 4.27Å; Y223-W380 AromaticContact CD1-CD1 3.65Å; Y223-W380 HydrophobicContact CE1-CB 4.33Å; Y223-W380 AromaticContact CE1-CD1 3.91Å; Y223-W380 HydrophobicContact CE1-CG 4.46Å; Y223-L421 HydrophobicContact CE1-CB 3.94Å; Y223-L421 HydrophobicContact CE1-CD1 4.25Å; Y223-L421 PolarHBondContact OH-O 3.22Å; Y223-A425 HydrophobicContact CE2-CB 3.72Å
224	V	93.6	Very high	91.6	Very high	1 Å²	1	15 Å²	15	1%	0.006	9%	0.085	C	C	.	.	H	α-helix	trans	-65	-42.5	175.1	177.7	0	0	0	0	111.6	S48 I52 K220 A221 F222 I372	S48-V224 VanDerWaalsContact CA-CG1 3.48Å; S48-V224 WeakPolarHBondContact CB-O 3.45Å; S48-V224 PolarHBondContact OG-O 3.41Å; I52-V224 HydrophobicContact CG1-CB 4.22Å; I52-V224 HydrophobicContact CG1-CG1 4.02Å; K220-V224 WeakPolarHBondContact O-CG2 3.09Å; K220-V224 PolarHBondContact O-N 2.8Å; K220-V224 VanDerWaalsContact O-N 3.09Å; A221-V224 PolarHBondContact O-N 2.87Å; F222-V224 VanDerWaalsContact C-N 3.35Å; F222-V224 PolarHBondContact O-N 3.44Å; V224-I372 HydrophobicContact CB-CG2 4.35Å; V224-I372 HydrophobicContact CG2-CG2 3.93Å
225	G	95.3	Very high	90.8	Very high	0 Å²	0	12.9 Å²	12.9	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-66.8	-47.4	176.4	0	0	0	0	0	112.3	A221 F222 F227 A228 Y229	A221-G225 PolarHBondContact O-N 3.18Å; F222-G225 PolarHBondContact O-N 2.95Å; G225-F227 VanDerWaalsContact C-N 3.25Å; G225-F227 PolarHBondContact O-N 3.21Å; G225-A228 WeakPolarHBondContact O-CB 3.45Å; G225-A228 PolarHBondContact O-N 3.44Å; G225-Y229 WeakPolarHBondContact O-CD2 3.37Å; G225-Y229 PolarHBondContact O-N 3.43Å
226	L	94.4	Very high	90.1	Very high	0 Å²	0	10.5 Å²	10.5	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-64.8	-28.4	-179.7	-72.7	179.5	0	0	0	112.9	C69 F72 F222 A228 Y229 S230 W380 L421	C69-L226 HydrophobicContact CB-CD2 3.79Å; C69-L226 HydrophobicContact CB-CG 4.29Å; F72-L226 HydrophobicContact CD1-CD1 3.89Å; F72-L226 HydrophobicContact CD1-CD2 3.57Å; F72-L226 HydrophobicContact CD1-CG 4.39Å; F72-L226 HydrophobicContact CE1-CD1 3.77Å; F72-L226 HydrophobicContact CE1-CD2 4.21Å; F222-L226 HydrophobicContact CD1-CD1 3.84Å; F222-L226 HydrophobicContact CD1-CG 3.99Å; F222-L226 WeakPolarHBondContact O-CB 3.49Å; F222-L226 WeakPolarHBondContact O-CG 3.4Å; F222-L226 PolarHBondContact O-N 3.34Å; L226-A228 PolarHBondContact O-N 3.34Å; L226-Y229 CarbonylContact O-C 3.53Å; L226-Y229 PolarHBondContact O-N 3.09Å; L226-S230 PolarHBondContact O-N 2.93Å; L226-W380 HydrophobicContact CB-CD2 4.35Å; L226-W380 VanDerWaalsContact CB-CE2 3.44Å; L226-W380 HydrophobicContact CB-CH2 4.28Å; L226-W380 HydrophobicContact CB-CZ2 3.46Å; L226-W380 VanDerWaalsContact CB-CZ2 3.46Å; L226-W380 HydrophobicContact CD1-CD2 3.79Å; L226-W380 HydrophobicContact CD1-CE3 4.32Å; L226-W380 HydrophobicContact CD1-CG 4Å; L226-W380 HydrophobicContact CD1-CZ2 4.3Å; L226-W380 HydrophobicContact CD2-CH2 4.48Å; L226-W380 HydrophobicContact CD2-CZ2 4.43Å; L226-W380 HydrophobicContact CG-CZ2 4.28Å; L226-W380 WeakPolarHBondContact O-CZ2 3.42Å; L226-L421 HydrophobicContact CD1-CD1 4.12Å
227	F	92.4	Very high	89.2	Confident	17 Å²	17	11.7 Å²	11.7	8%	0.075	6%	0.06	C	C	.	.	H	α-helix	trans	-54.7	-41.5	168.8	175	-105.6	0	0	0	111.7	I124 M125 Y223 G225 Y229 S230 I372 L375	I124-F227 HydrophobicContact CB-CZ 4.14Å; I124-F227 HydrophobicContact CD1-CE2 4.08Å; I124-F227 HydrophobicContact CD1-CZ 4.47Å; I124-F227 HydrophobicContact CG2-CE1 3.78Å; I124-F227 HydrophobicContact CG2-CE2 4.1Å; I124-F227 HydrophobicContact CG2-CZ 3.38Å; M125-F227 HydrophobicContact CG-CZ 4.48Å; Y223-F227 WeakPolarHBondContact O-CB 3.22Å; Y223-F227 PolarHBondContact O-N 2.98Å; G225-F227 VanDerWaalsContact C-N 3.25Å; G225-F227 PolarHBondContact O-N 3.21Å; F227-Y229 VanDerWaalsContact C-N 3.3Å; F227-Y229 PolarHBondContact O-N 3.12Å; F227-S230 VanDerWaalsContact O-CB 3.29Å; F227-S230 WeakPolarHBondContact O-CB 3.44Å; F227-S230 PolarHBondContact O-N 3.46Å; F227-I372 HydrophobicContact CB-CG2 4.01Å; F227-I372 HydrophobicContact CD1-CD1 4.21Å; F227-I372 HydrophobicContact CD1-CG1 4.35Å; F227-I372 HydrophobicContact CE1-CD1 4.46Å; F227-I372 HydrophobicContact CG-CG1 4.33Å; F227-I372 HydrophobicContact CG-CG2 4.35Å; F227-L375 HydrophobicContact CD2-CD2 3.73Å; F227-L375 HydrophobicContact CE2-CD2 3.8Å
228	A	93.3	Very high	88.2	Confident	3 Å²	3	13.1 Å²	13.1	3%	0.025	7%	0.067	C	C	.	.	H	α-helix	trans	-71	-23.6	176.7	0	0	0	0	0	113.9	M40 W66 G225 L226 Y264	M40-A228 VanDerWaalsContact O-O 3.11Å; W66-A228 HydrophobicContact CH2-CB 3.64Å; W66-A228 HydrophobicContact CZ3-CB 3.65Å; G225-A228 WeakPolarHBondContact O-CB 3.45Å; G225-A228 PolarHBondContact O-N 3.44Å; L226-A228 PolarHBondContact O-N 3.34Å; A228-Y264 HydrophobicContact CB-CE2 3.91Å; A228-Y264 VanDerWaalsContact O-CE2 3.22Å; A228-Y264 WeakPolarHBondContact O-CE2 3.44Å; A228-Y264 PolarHBondContact O-OH 3.42Å
229	Y	92.7	Very high	87.4	Confident	0 Å²	0	11.8 Å²	11.8	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-91.2	0.6	174.6	-73	-87.4	0	0	0	113.5	M40 W66 C69 G70 S73 G225 L226 F227 V260 T261 Y264	M40-Y229 HydrophobicContact CE-CD1 3.51Å; M40-Y229 HydrophobicContact CE-CE1 4.49Å; M40-Y229 HydrophobicContact CE-CG 4.24Å; M40-Y229 WeakPolarHBondContact CE-O 3.28Å; W66-Y229 AromaticContact CE3-CE2 3.61Å; W66-Y229 HydrophobicContact CE3-CE2 3.61Å; W66-Y229 HydrophobicContact CZ3-CD2 4.49Å; W66-Y229 AromaticContact CZ3-CE2 3.91Å; W66-Y229 HydrophobicContact CZ3-CE2 3.91Å; W66-Y229 PolarHBondContact O-OH 3.28Å; C69-Y229 HydrophobicContact CB-CD2 3.65Å; C69-Y229 HydrophobicContact CB-CE2 3.63Å; G70-Y229 VanDerWaalsContact CA-CE1 3.41Å; S73-Y229 WeakPolarHBondContact OG-CB 3.37Å; G225-Y229 WeakPolarHBondContact O-CD2 3.37Å; G225-Y229 PolarHBondContact O-N 3.43Å; L226-Y229 CarbonylContact O-C 3.53Å; L226-Y229 PolarHBondContact O-N 3.09Å; F227-Y229 VanDerWaalsContact C-N 3.3Å; F227-Y229 PolarHBondContact O-N 3.12Å; Y229-V260 HydrophobicContact CD1-CG1 4.1Å; Y229-V260 HydrophobicContact CE1-CG1 3.92Å; Y229-T261 WeakPolarHBondContact CE1-OG1 3.27Å; Y229-T261 WeakPolarHBondContact OH-CA 3.2Å; Y229-Y264 HydrophobicContact CD1-CD2 4.37Å; Y229-Y264 HydrophobicContact CD1-CE2 4.31Å; Y229-Y264 HydrophobicContact CD2-CD2 4.35Å; Y229-Y264 HydrophobicContact CD2-CE2 4.42Å; Y229-Y264 AromaticContact CE1-CD2 3.86Å; Y229-Y264 HydrophobicContact CE1-CD2 3.86Å; Y229-Y264 HydrophobicContact CE1-CE2 4.24Å; Y229-Y264 AromaticContact CE2-CD2 3.86Å; Y229-Y264 HydrophobicContact CE2-CD2 3.86Å; Y229-Y264 HydrophobicContact CE2-CE2 4.37Å; Y229-Y264 HydrophobicContact CG-CE2 4.39Å; Y229-Y264 AromaticContact CZ-CD2 3.57Å
230	S	88.3	Confident	86.5	Confident	17 Å²	17	14.8 Å²	14.8	12%	0.119	7%	0.073	C	C	.	.	T	Hydrogen-bonded Turn	trans	-61.6	147	178.4	-173.2	0	0	0	0	111.9	M40 L226 F227 Q379	M40-S230 WeakPolarHBondContact CA-O 3.41Å; L226-S230 PolarHBondContact O-N 2.93Å; F227-S230 VanDerWaalsContact O-CB 3.29Å; F227-S230 WeakPolarHBondContact O-CB 3.44Å; F227-S230 PolarHBondContact O-N 3.46Å; S230-Q379 PolarHBondContact OG-NE2 3.36Å
231	G	83.6	Confident	85.9	Confident	1 Å²	1	14 Å²	14	1%	0.01	7%	0.071	C	C	.	.	T	Hydrogen-bonded Turn	trans	109.9	-8.4	175	0	0	0	0	0	115.7	N233 Y234	G231-N233 PolarHBondContact O-N 3.19Å; G231-Y234 WeakPolarHBondContact O-CB 3.48Å; G231-Y234 PolarHBondContact O-N 3.12Å
232	W	88.5	Confident	85.3	Confident	2 Å²	2	14 Å²	14	1%	0.008	7%	0.071	C	C	.	.	G	3₁₀ helix	trans	-63.1	-26.1	175.1	57.7	-105.3	0	0	0	113.3	I36 M40 G76 A77 Y80 Y234 W380 I383	I36-W232 HydrophobicContact CG2-CB 4.36Å; M40-W232 HydrophobicContact CE-CB 4.29Å; M40-W232 HydrophobicContact CG-CB 4.13Å; M40-W232 HydrophobicContact SD-CB 3.78Å; G76-W232 VanDerWaalsContact C-CH2 3.49Å; A77-W232 HydrophobicContact CB-CB 4.48Å; A77-W232 HydrophobicContact CB-CD2 3.76Å; A77-W232 HydrophobicContact CB-CE3 3.37Å; A77-W232 HydrophobicContact CB-CG 4.24Å; A77-W232 HydrophobicContact CB-CZ3 3.9Å; Y80-W232 HydrophobicContact CD1-CZ3 4.01Å; Y80-W232 AromaticContact CD2-CH2 3.66Å; Y80-W232 HydrophobicContact CD2-CH2 3.66Å; Y80-W232 AromaticContact CD2-CZ3 3.75Å; Y80-W232 HydrophobicContact CD2-CZ3 3.75Å; Y80-W232 HydrophobicContact CE1-CZ3 4.44Å; Y80-W232 AromaticContact CE2-CH2 3.83Å; Y80-W232 HydrophobicContact CE2-CH2 3.83Å; Y80-W232 HydrophobicContact CE2-CZ3 4.25Å; Y80-W232 HydrophobicContact CG-CH2 4.02Å; Y80-W232 AromaticContact CG-CZ3 3.6Å; Y80-W232 HydrophobicContact CG-CZ3 3.6Å; W232-Y234 VanDerWaalsContact C-N 3.26Å; W232-Y234 PolarHBondContact O-N 3.28Å; W232-W380 HydrophobicContact CZ2-CZ3 4.31Å; W232-I383 HydrophobicContact CH2-CG2 4Å; W232-I383 HydrophobicContact CZ2-CD1 4.48Å; W232-I383 HydrophobicContact CZ2-CG2 4.02Å
233	N	85.3	Confident	84.9	Confident	4 Å²	4	17 Å²	17	2%	0.021	9%	0.088	C	C	.	.	G	3₁₀ helix	trans	-74.3	-15.3	-178.2	60.3	-36.7	0	0	0	113.1	Y80 D93 G231 L235 N236	Y80-N233 HydrophobicContact CD1-CB 4.2Å; Y80-N233 HydrophobicContact CE1-CB 4.05Å; D93-N233 PolarHBondContact OD1-ND2 2.93Å; D93-N233 PolarHBondContact OD2-ND2 3.04Å; G231-N233 PolarHBondContact O-N 3.19Å; N233-L235 VanDerWaalsContact C-N 3.3Å; N233-L235 PolarHBondContact O-N 2.83Å; N233-N236 WeakPolarHBondContact O-CB 3.45Å; N233-N236 PolarHBondContact O-N 3.43Å; N233-N236 VanDerWaalsContact O-N 3.16Å; N233-N236 PolarHBondContact O-ND2 3.08Å
234	Y	75.2	Confident	84.6	Confident	32 Å²	32	20.3 Å²	20.3	13%	0.125	11%	0.106	C	C	.	.	G	3₁₀ helix	trans	-64.4	-30.8	-174.7	-63.6	-8.8	0	0	0	113.6	R118 G231 W232 N236 C237	R118-Y234 PolarHBondContact NH1-OH 2.98Å; G231-Y234 WeakPolarHBondContact O-CB 3.48Å; G231-Y234 PolarHBondContact O-N 3.12Å; W232-Y234 VanDerWaalsContact C-N 3.26Å; W232-Y234 PolarHBondContact O-N 3.28Å; Y234-N236 PolarHBondContact O-N 3.3Å; Y234-C237 WeakPolarHBondContact O-CB 3.49Å; Y234-C237 PolarHBondContact O-N 2.92Å
235	L	77.2	Confident	84.3	Confident	1 Å²	1	21.2 Å²	21.2	1%	0.005	11%	0.112	C	C	.	.	G	3₁₀ helix	trans	-63.4	-29.4	178.7	-170.8	65.3	0	0	0	111.9	I35 I36 N233 C237 M238 I239 M242 L249 A252	I35-L235 HydrophobicContact CG2-CD1 4.26Å; I36-L235 HydrophobicContact CD1-CB 4.19Å; I36-L235 HydrophobicContact CD1-CD2 3.48Å; I36-L235 VanDerWaalsContact CD1-CD2 3.48Å; I36-L235 HydrophobicContact CD1-CG 4.45Å; I36-L235 HydrophobicContact CG1-CB 3.92Å; I36-L235 HydrophobicContact CG1-CD2 3.88Å; I36-L235 HydrophobicContact CG1-CG 4.45Å; N233-L235 VanDerWaalsContact C-N 3.3Å; N233-L235 PolarHBondContact O-N 2.83Å; L235-C237 PolarHBondContact O-N 3.24Å; L235-M238 CarbonylContact O-C 3.53Å; L235-M238 PolarHBondContact O-N 3.42Å; L235-I239 PolarHBondContact O-N 3.37Å; L235-M242 HydrophobicContact CD1-SD 4.19Å; L235-M242 HydrophobicContact CD2-CE 4.3Å; L235-M242 HydrophobicContact CD2-SD 4.25Å; L235-M242 HydrophobicContact CG-SD 4.04Å; L235-L249 HydrophobicContact CB-CD1 4.45Å; L235-L249 HydrophobicContact CD2-CD1 3.51Å; L235-L249 HydrophobicContact CG-CD1 3.91Å; L235-A252 HydrophobicContact CD2-CB 4.21Å
236	N	79.9	Confident	84.1	Confident	2 Å²	2	29.4 Å²	29.4	1%	0.011	14%	0.143	C	C	.	.	G	3₁₀ helix	trans	-65.5	-26.8	176.5	-62.3	-65.4	0	0	0	112.6	Y80 N233 Y234 M238	Y80-N236 WeakPolarHBondContact CB-ND2 3.4Å; Y80-N236 PolarHBondContact O-OD1 3.42Å; N233-N236 WeakPolarHBondContact O-CB 3.45Å; N233-N236 PolarHBondContact O-N 3.43Å; N233-N236 VanDerWaalsContact O-N 3.16Å; N233-N236 PolarHBondContact O-ND2 3.08Å; Y234-N236 PolarHBondContact O-N 3.3Å; N236-M238 PolarHBondContact O-N 3.2Å
237	C	72.4	Confident	84	Confident	39 Å²	39	35.8 Å²	35.8	26%	0.264	17%	0.167	S	C	.	.	G	3₁₀ helix	trans	-72.5	-17.1	174.7	-60.8	0	0	0	0	112.9	Y234 L235	Y234-C237 WeakPolarHBondContact O-CB 3.49Å; Y234-C237 PolarHBondContact O-N 2.92Å; L235-C237 PolarHBondContact O-N 3.24Å
238	M	73.1	Confident	84	Confident	36 Å²	36	35.6 Å²	35.6	18%	0.177	17%	0.167	C	C	.	.	G	3₁₀ helix	trans	-110.3	18.3	-178	-61	175.3	-179.5	0	0	111.8	I27 L235 N236 E240 E241 M242	I27-M238 HydrophobicContact CD1-CB 4.15Å; I27-M238 HydrophobicContact CD1-SD 4.47Å; L235-M238 CarbonylContact O-C 3.53Å; L235-M238 PolarHBondContact O-N 3.42Å; N236-M238 PolarHBondContact O-N 3.2Å; M238-E240 PolarHBondContact O-N 2.94Å; M238-E241 WeakPolarHBondContact O-CB 3.41Å; M238-E241 PolarHBondContact O-N 3.28Å; M238-M242 PolarHBondContact O-N 2.9Å
239	I	77.7	Confident	83.8	Confident	3 Å²	3	35.5 Å²	35.5	2%	0.015	17%	0.165	C	C	.	.	G	3₁₀ helix	trans	-64.9	-28.9	-173	-157	165.7	0	0	0	112.9	G84 T85 L235 E241 M242 P245 L249	G84-I239 VanDerWaalsContact C-CD1 3.41Å; G84-I239 WeakPolarHBondContact O-CD1 3.29Å; T85-I239 HydrophobicContact CG2-CD1 3.83Å; L235-I239 PolarHBondContact O-N 3.37Å; I239-E241 VanDerWaalsContact C-N 3.27Å; I239-E241 PolarHBondContact O-N 3.19Å; I239-M242 HydrophobicContact CG1-SD 4.31Å; I239-M242 PolarHBondContact O-N 3.41Å; I239-P245 HydrophobicContact CD1-CB 4.13Å; I239-P245 HydrophobicContact CG1-CB 3.74Å; I239-P245 HydrophobicContact CG1-CG 4.14Å; I239-L249 HydrophobicContact CD1-CD2 3.53Å; I239-L249 HydrophobicContact CG1-CD2 4.33Å
240	E	76	Confident	83.8	Confident	63 Å²	63	36.2 Å²	36.2	29%	0.294	17%	0.17	S	C	.	.	G	3₁₀ helix	trans	-68.6	-26	175.9	-69.2	176.3	-173.4	0	0	112.4	L23 K25 R89 S90 M238	L23-E240 HydrophobicContact CD1-CB 4.5Å; K25-E240 WeakPolarHBondContact CG-O 3.5Å; R89-E240 WeakPolarHBondContact CA-OE1 3.04Å; S90-E240 PolarHBondContact N-OE1 3.07Å; S90-E240 PolarHBondContact OG-OE1 3.18Å; S90-E240 PolarHBondContact OG-OE2 3.47Å; M238-E240 PolarHBondContact O-N 2.94Å
241	E	79.6	Confident	84.1	Confident	48 Å²	48	38.4 Å²	38.4	22%	0.224	18%	0.18	C	C	.	.	G	3₁₀ helix	trans	-86.4	-6.7	178	-65.6	175.2	-121.5	0	0	112.7	L23 K25 T26 I27 M238 I239	L23-E241 HydrophobicContact CB-CG 3.87Å; L23-E241 HydrophobicContact CD1-CG 4.16Å; L23-E241 HydrophobicContact CD2-CG 4.45Å; L23-E241 HydrophobicContact CG-CG 4.39Å; K25-E241 CarbonylContact C-O 3.23Å; K25-E241 VanDerWaalsContact CA-O 3.31Å; K25-E241 WeakPolarHBondContact CA-O 3.42Å; T26-E241 PolarHBondContact N-O 3.47Å; I27-E241 HydrophobicContact CD1-CB 3.66Å; I27-E241 HydrophobicContact CG1-CB 4.09Å; I27-E241 PolarHBondContact N-O 3Å; M238-E241 WeakPolarHBondContact O-CB 3.41Å; M238-E241 PolarHBondContact O-N 3.28Å; I239-E241 VanDerWaalsContact C-N 3.27Å; I239-E241 PolarHBondContact O-N 3.19Å
242	M	83.6	Confident	84.6	Confident	0 Å²	0	38.4 Å²	38.4	0%	0	18%	0.18	C	C	.	.	B	Isolated β-bridge	trans	-81.9	138.2	-179.9	-67.1	-178.4	70.3	0	0	112.6	I27 S32 L235 M238 I239 P245 D248 L249	I27-M242 HydrophobicContact CB-CG 4.29Å; I27-M242 HydrophobicContact CG2-CG 4.26Å; I27-M242 WeakPolarHBondContact O-CA 3.47Å; S32-M242 WeakPolarHBondContact OG-CE 3.33Å; L235-M242 HydrophobicContact CD1-SD 4.19Å; L235-M242 HydrophobicContact CD2-CE 4.3Å; L235-M242 HydrophobicContact CD2-SD 4.25Å; L235-M242 HydrophobicContact CG-SD 4.04Å; M238-M242 PolarHBondContact O-N 2.9Å; I239-M242 HydrophobicContact CG1-SD 4.31Å; I239-M242 PolarHBondContact O-N 3.41Å; M242-P245 HydrophobicContact CB-CG 3.99Å; M242-D248 HydrophobicContact CE-CB 4.06Å; M242-L249 HydrophobicContact CE-CB 3.96Å; M242-L249 HydrophobicContact CE-CD1 4.42Å; M242-L249 HydrophobicContact SD-CB 4.43Å; M242-L249 HydrophobicContact SD-CD1 4.22Å
243	N	86.6	Confident	84.9	Confident	85 Å²	85	38.4 Å²	38.4	46%	0.455	18%	0.18	S	C	.	.	S	Bend	trans	-66.5	-49.3	-179.7	-68.3	-19.6	0	0	0	112.1	K25 T26 I27	K25-N243 VanDerWaalsContact C-OD1 3.22Å; K25-N243 PolarHBondContact O-OD1 2.91Å; T26-N243 PolarHBondContact N-OD1 2.9Å; I27-N243 PolarHBondContact O-N 3.24Å
244	N	88.6	Confident	85.3	Confident	72 Å²	72	41 Å²	41	39%	0.385	19%	0.194	S	C	.	.			trans	-135.3	78.9	178	-172.6	-7.9	0	0	0	111.5	R246 R247 D248	N244-R246 PolarHBondContact O-N 2.83Å; N244-R246 VanDerWaalsContact O-N 3.17Å; N244-R246 PolarHBondContact OD1-N 3.23Å; N244-R247 PolarHBondContact O-N 3.39Å; N244-R247 PolarHBondContact OD1-N 3.43Å; N244-D248 VanDerWaalsContact O-CB 3.32Å; N244-D248 WeakPolarHBondContact O-CB 3.45Å; N244-D248 PolarHBondContact O-N 3.43Å
245	P	86.9	Confident	86.3	Confident	20 Å²	20	43.1 Å²	43.1	13%	0.13	21%	0.206	C	C	.	.	H	α-helix	trans	-56	-34.8	-178.6	-21.3	28.1	0	0	0	113.5	T85 I239 M242 R247 L249	T85-P245 HydrophobicContact CG2-CB 4.28Å; I239-P245 HydrophobicContact CD1-CB 4.13Å; I239-P245 HydrophobicContact CG1-CB 3.74Å; I239-P245 HydrophobicContact CG1-CG 4.14Å; M242-P245 HydrophobicContact CB-CG 3.99Å; P245-R247 VanDerWaalsContact C-N 3.34Å; P245-R247 PolarHBondContact O-N 3.27Å; P245-L249 WeakPolarHBondContact O-CB 3.43Å; P245-L249 PolarHBondContact O-N 3.4Å
246	R	90.6	Very high	87.1	Confident	173 Å²	173	43 Å²	43	65%	0.653	21%	0.206	S	C	*	.	H	α-helix	trans	-62.8	-39.7	-176	-175.9	178.3	-179.4	-165.1	-4.3	112.8	N244 P250 P403 V404	N244-R246 PolarHBondContact O-N 2.83Å; N244-R246 VanDerWaalsContact O-N 3.17Å; N244-R246 PolarHBondContact OD1-N 3.23Å; R246-P250 WeakPolarHBondContact O-CG 3.38Å; R246-P403 HydrophobicContact CB-CB 4.29Å; R246-P403 HydrophobicContact CG-CB 3.94Å; R246-P403 WeakPolarHBondContact CG-O 3.37Å; R246-P403 PolarHBondContact NE-O 3.31Å; R246-V404 WeakPolarHBondContact O-CG2 3.02Å
247	R	91.9	Very high	87.8	Confident	133 Å²	133	43 Å²	43	50%	0.502	21%	0.206	S	C	.	.	H	α-helix	trans	-96	-47.7	-179.1	178.7	-175	172.5	-85.6	2.3	111.6	N244 P245 P250 L251	N244-R247 PolarHBondContact O-N 3.39Å; N244-R247 PolarHBondContact OD1-N 3.43Å; P245-R247 VanDerWaalsContact C-N 3.34Å; P245-R247 PolarHBondContact O-N 3.27Å; R247-P250 WeakPolarHBondContact O-CD 3.27Å; R247-P250 WeakPolarHBondContact O-CG 3.49Å; R247-L251 HydrophobicContact CG-CD1 3.87Å; R247-L251 WeakPolarHBondContact O-CG 3.47Å
248	D	92.1	Very high	89	Confident	14 Å²	14	45.4 Å²	45.4	8%	0.075	22%	0.215	C	C	.	.	H	α-helix	trans	-78.5	-31.5	-165.1	-64.6	-12.2	0	0	0	111.7	L29 M242 N244 A252	L29-D248 HydrophobicContact CB-CB 4.14Å; L29-D248 HydrophobicContact CD1-CB 4.15Å; L29-D248 WeakPolarHBondContact CD1-O 3.25Å; M242-D248 HydrophobicContact CE-CB 4.06Å; N244-D248 VanDerWaalsContact O-CB 3.32Å; N244-D248 WeakPolarHBondContact O-CB 3.45Å; N244-D248 PolarHBondContact O-N 3.43Å; D248-A252 WeakPolarHBondContact O-CB 3.33Å; D248-A252 PolarHBondContact O-N 3.28Å
249	L	90.9	Very high	90	Very high	0 Å²	0	47.2 Å²	47.2	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-62.5	-55	178	-175.3	58.5	0	0	0	113.3	A81 T85 L235 I239 M242 P245 L251 A252 I253	A81-L249 HydrophobicContact CB-CD2 3.85Å; A81-L249 HydrophobicContact CB-CG 3.9Å; T85-L249 HydrophobicContact CG2-CD2 4.12Å; L235-L249 HydrophobicContact CB-CD1 4.45Å; L235-L249 HydrophobicContact CD2-CD1 3.51Å; L235-L249 HydrophobicContact CG-CD1 3.91Å; I239-L249 HydrophobicContact CD1-CD2 3.53Å; I239-L249 HydrophobicContact CG1-CD2 4.33Å; M242-L249 HydrophobicContact CE-CB 3.96Å; M242-L249 HydrophobicContact CE-CD1 4.42Å; M242-L249 HydrophobicContact SD-CB 4.43Å; M242-L249 HydrophobicContact SD-CD1 4.22Å; P245-L249 WeakPolarHBondContact O-CB 3.43Å; P245-L249 PolarHBondContact O-N 3.4Å; L249-L251 VanDerWaalsContact C-N 3.32Å; L249-L251 PolarHBondContact O-N 2.84Å; L249-A252 PolarHBondContact O-N 3.24Å; L249-I253 HydrophobicContact CD1-CD1 3.86Å; L249-I253 HydrophobicContact CD1-CG1 4.39Å; L249-I253 HydrophobicContact CG-CD1 3.95Å; L249-I253 WeakPolarHBondContact O-CD1 3.24Å; L249-I253 WeakPolarHBondContact O-CG1 3.41Å; L249-I253 PolarHBondContact O-N 3.4Å
250	P	92.6	Very high	90.8	Very high	15 Å²	15	47 Å²	47	10%	0.097	22%	0.224	C	C	.	.	H	α-helix	trans	-64.5	-36.4	-179.7	24.3	-33.9	0	0	0	112.4	Y78 R246 R247 I254 V404	Y78-P250 HydrophobicContact CE2-CB 3.76Å; R246-P250 WeakPolarHBondContact O-CG 3.38Å; R247-P250 WeakPolarHBondContact O-CD 3.27Å; R247-P250 WeakPolarHBondContact O-CG 3.49Å; P250-I254 WeakPolarHBondContact O-CG1 3.28Å; P250-I254 PolarHBondContact O-N 2.71Å; P250-I254 VanDerWaalsContact O-N 3.11Å; P250-V404 HydrophobicContact CG-CG2 4.22Å
251	L	94.9	Very high	91.8	Very high	64 Å²	64	44.8 Å²	44.8	34%	0.335	22%	0.215	S	C	.	.	H	α-helix	trans	-65.7	-46.2	175.6	-71.5	178.1	0	0	0	111.6	L29 R247 L249 I253 I254 I255	L29-L251 HydrophobicContact CD1-CB 3.88Å; L29-L251 HydrophobicContact CD2-CD1 4.38Å; R247-L251 HydrophobicContact CG-CD1 3.87Å; R247-L251 WeakPolarHBondContact O-CG 3.47Å; L249-L251 VanDerWaalsContact C-N 3.32Å; L249-L251 PolarHBondContact O-N 2.84Å; L251-I253 VanDerWaalsContact C-N 3.29Å; L251-I253 PolarHBondContact O-N 3.13Å; L251-I254 PolarHBondContact O-N 2.85Å; L251-I255 WeakPolarHBondContact O-CB 3.41Å; L251-I255 WeakPolarHBondContact O-CD1 3.49Å; L251-I255 VanDerWaalsContact O-CG1 3.26Å; L251-I255 WeakPolarHBondContact O-CG1 3.39Å; L251-I255 PolarHBondContact O-N 3.49Å
252	A	93.4	Very high	92.6	Very high	0 Å²	0	47.9 Å²	47.9	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-59.9	-42.3	178.2	0	0	0	0	0	111.1	L29 I33 I36 L235 D248 L249 S256	L29-A252 HydrophobicContact CD1-CB 4.05Å; I33-A252 HydrophobicContact CG1-CB 4.03Å; I36-A252 HydrophobicContact CD1-CB 4.07Å; L235-A252 HydrophobicContact CD2-CB 4.21Å; D248-A252 WeakPolarHBondContact O-CB 3.33Å; D248-A252 PolarHBondContact O-N 3.28Å; L249-A252 PolarHBondContact O-N 3.24Å; A252-S256 WeakPolarHBondContact O-CB 3.26Å; A252-S256 PolarHBondContact O-N 2.87Å; A252-S256 PolarHBondContact O-OG 3.33Å
253	I	93.5	Very high	93.2	Very high	2 Å²	2	49.2 Å²	49.2	1%	0.01	24%	0.235	C	C	.	.	H	α-helix	trans	-61.5	-52.6	177.8	-74.6	162.3	0	0	0	111.7	I36 A77 A81 L249 L251 S256 C257	I36-I253 HydrophobicContact CD1-CG1 3.98Å; A77-I253 HydrophobicContact CB-CB 4.4Å; A77-I253 HydrophobicContact CB-CD1 4.34Å; A77-I253 HydrophobicContact CB-CG1 4.22Å; A77-I253 HydrophobicContact CB-CG2 3.35Å; A77-I253 WeakPolarHBondContact O-CD1 3.5Å; A81-I253 HydrophobicContact CB-CD1 3.66Å; L249-I253 HydrophobicContact CD1-CD1 3.86Å; L249-I253 HydrophobicContact CD1-CG1 4.39Å; L249-I253 HydrophobicContact CG-CD1 3.95Å; L249-I253 WeakPolarHBondContact O-CD1 3.24Å; L249-I253 WeakPolarHBondContact O-CG1 3.41Å; L249-I253 PolarHBondContact O-N 3.4Å; L251-I253 VanDerWaalsContact C-N 3.29Å; L251-I253 PolarHBondContact O-N 3.13Å; I253-S256 PolarHBondContact O-N 2.87Å; I253-C257 VanDerWaalsContact O-CB 3.3Å; I253-C257 WeakPolarHBondContact O-CB 3.46Å; I253-C257 PolarHBondContact O-N 2.76Å; I253-C257 PolarHBondContact O-SG 2.69Å
254	I	95.1	Very high	93.6	Very high	60 Å²	60	45.1 Å²	45.1	31%	0.308	21%	0.213	S	C	.	.	H	α-helix	trans	-62.4	-50.7	-176.9	-69.3	169.5	0	0	0	110.2	Y78 P250 L251 S256 C257 L258	Y78-I254 HydrophobicContact CD2-CD1 4.17Å; Y78-I254 HydrophobicContact CD2-CG1 4.22Å; Y78-I254 HydrophobicContact CE2-CD1 3.8Å; Y78-I254 HydrophobicContact CE2-CG1 4.34Å; P250-I254 WeakPolarHBondContact O-CG1 3.28Å; P250-I254 PolarHBondContact O-N 2.71Å; P250-I254 VanDerWaalsContact O-N 3.11Å; L251-I254 PolarHBondContact O-N 2.85Å; I254-S256 VanDerWaalsContact C-N 3.33Å; I254-S256 PolarHBondContact O-N 3.49Å; I254-C257 PolarHBondContact O-N 3.39Å; I254-L258 HydrophobicContact CG2-CD1 3.74Å; I254-L258 HydrophobicContact CG2-CG 4.42Å; I254-L258 WeakPolarHBondContact O-CB 3.46Å; I254-L258 VanDerWaalsContact O-CG 3.29Å; I254-L258 WeakPolarHBondContact O-CG 3.34Å; I254-L258 PolarHBondContact O-N 3.49Å
255	I	96.1	Very high	93.9	Very high	75 Å²	75	42.7 Å²	42.7	39%	0.385	20%	0.2	S	C	.	.	H	α-helix	trans	-60.8	-46	-177.9	-65.6	167	0	0	0	110.1	I33 L251 L259	I33-I255 HydrophobicContact CD1-CB 4.3Å; I33-I255 HydrophobicContact CD1-CD1 3.94Å; I33-I255 HydrophobicContact CD1-CG2 4.02Å; I33-I255 HydrophobicContact CG1-CG2 4.43Å; I33-I255 HydrophobicContact CG2-CG2 4.33Å; L251-I255 WeakPolarHBondContact O-CB 3.41Å; L251-I255 WeakPolarHBondContact O-CD1 3.49Å; L251-I255 VanDerWaalsContact O-CG1 3.26Å; L251-I255 WeakPolarHBondContact O-CG1 3.39Å; L251-I255 PolarHBondContact O-N 3.49Å; I255-L259 WeakPolarHBondContact O-CB 3.36Å; I255-L259 PolarHBondContact O-N 2.96Å
256	S	93.7	Very high	94.4	Very high	0 Å²	0	43.9 Å²	43.9	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-68.3	-45.3	-177.4	-54.1	0	0	0	0	112.1	I33 A252 I253 I254 L258 L259 V260	I33-S256 WeakPolarHBondContact CA-OG 3.45Å; A252-S256 WeakPolarHBondContact O-CB 3.26Å; A252-S256 PolarHBondContact O-N 2.87Å; A252-S256 PolarHBondContact O-OG 3.33Å; I253-S256 PolarHBondContact O-N 2.87Å; I254-S256 VanDerWaalsContact C-N 3.33Å; I254-S256 PolarHBondContact O-N 3.49Å; S256-L258 PolarHBondContact O-N 2.82Å; S256-L259 PolarHBondContact O-N 2.99Å; S256-V260 WeakPolarHBondContact O-CB 3.11Å; S256-V260 VanDerWaalsContact O-CG2 3.22Å; S256-V260 WeakPolarHBondContact O-CG2 3.23Å; S256-V260 PolarHBondContact O-N 2.97Å
257	C	94.9	Very high	94.6	Very high	1 Å²	1	35.6 Å²	35.6	1%	0.007	17%	0.174	C	C	.	.	H	α-helix	trans	-64	-42.4	-179.7	-67.4	0	0	0	0	111.5	M74 I253 I254 T261	M74-C257 HydrophobicContact CB-CB 3.78Å; M74-C257 HydrophobicContact CG-CB 4.03Å; I253-C257 VanDerWaalsContact O-CB 3.3Å; I253-C257 WeakPolarHBondContact O-CB 3.46Å; I253-C257 PolarHBondContact O-N 2.76Å; I253-C257 PolarHBondContact O-SG 2.69Å; I254-C257 PolarHBondContact O-N 3.39Å; C257-T261 VanDerWaalsContact O-CB 3.3Å; C257-T261 WeakPolarHBondContact O-CB 3.32Å; C257-T261 PolarHBondContact O-N 2.94Å; C257-T261 PolarHBondContact O-OG1 2.95Å
258	L	96.5	Very high	94.7	Very high	90 Å²	90	29.7 Å²	29.7	47%	0.471	15%	0.152	S	C	.	.	H	α-helix	trans	-66.1	-43.7	176.7	-69.4	176	0	0	0	111.6	M74 I254 S256 T261 F262	M74-L258 HydrophobicContact SD-CD2 4.22Å; M74-L258 HydrophobicContact SD-CG 4.24Å; I254-L258 HydrophobicContact CG2-CD1 3.74Å; I254-L258 HydrophobicContact CG2-CG 4.42Å; I254-L258 WeakPolarHBondContact O-CB 3.46Å; I254-L258 VanDerWaalsContact O-CG 3.29Å; I254-L258 WeakPolarHBondContact O-CG 3.34Å; I254-L258 PolarHBondContact O-N 3.49Å; S256-L258 PolarHBondContact O-N 2.82Å; L258-T261 PolarHBondContact O-N 2.89Å; L258-F262 WeakPolarHBondContact O-CB 3.46Å; L258-F262 PolarHBondContact O-N 3.34Å
259	L	95	Very high	94.9	Very high	73 Å²	73	30.2 Å²	30.2	38%	0.382	16%	0.155	S	C	.	.	H	α-helix	trans	-62	-47.5	178	178.7	61.4	0	0	0	111.7	V37 I255 S256 T261 F262 I263	V37-L259 HydrophobicContact CG2-CD2 4.03Å; I255-L259 WeakPolarHBondContact O-CB 3.36Å; I255-L259 PolarHBondContact O-N 2.96Å; S256-L259 PolarHBondContact O-N 2.99Å; L259-T261 VanDerWaalsContact C-N 3.32Å; L259-T261 PolarHBondContact O-N 3.35Å; L259-F262 PolarHBondContact O-N 2.97Å; L259-I263 HydrophobicContact CD1-CD1 3.93Å; L259-I263 HydrophobicContact CD1-CG1 4.29Å; L259-I263 HydrophobicContact CG-CD1 3.86Å; L259-I263 VanDerWaalsContact O-CG1 3.28Å; L259-I263 WeakPolarHBondContact O-CG1 3.49Å; L259-I263 PolarHBondContact O-N 3.35Å
260	V	95	Very high	95.1	Very high	0 Å²	0	30.3 Å²	30.3	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-63.6	-40.9	177.8	174	0	0	0	0	110.5	V37 M40 I41 Y229 S256 F262 I263 Y264	V37-V260 HydrophobicContact CB-CG2 4.48Å; V37-V260 HydrophobicContact CG1-CG2 4.28Å; V37-V260 HydrophobicContact CG2-CG2 4.31Å; M40-V260 HydrophobicContact CB-CG1 4.27Å; M40-V260 HydrophobicContact CB-CG2 4.18Å; M40-V260 HydrophobicContact CE-CB 4.39Å; M40-V260 HydrophobicContact CE-CG1 4.15Å; M40-V260 HydrophobicContact SD-CG2 4.19Å; I41-V260 HydrophobicContact CD1-CG2 4.29Å; I41-V260 HydrophobicContact CG1-CG1 4.37Å; I41-V260 HydrophobicContact CG1-CG2 3.98Å; Y229-V260 HydrophobicContact CD1-CG1 4.1Å; Y229-V260 HydrophobicContact CE1-CG1 3.92Å; S256-V260 WeakPolarHBondContact O-CB 3.11Å; S256-V260 VanDerWaalsContact O-CG2 3.22Å; S256-V260 WeakPolarHBondContact O-CG2 3.23Å; S256-V260 PolarHBondContact O-N 2.97Å; V260-F262 VanDerWaalsContact C-N 3.34Å; V260-F262 PolarHBondContact O-N 3.38Å; V260-I263 PolarHBondContact O-N 3.46Å; V260-Y264 HydrophobicContact CG1-CD1 4.32Å; V260-Y264 HydrophobicContact CG1-CD2 3.69Å; V260-Y264 HydrophobicContact CG1-CE1 4.08Å; V260-Y264 HydrophobicContact CG1-CE2 3.42Å; V260-Y264 VanDerWaalsContact CG1-CE2 3.42Å; V260-Y264 HydrophobicContact CG1-CG 4.16Å; V260-Y264 WeakPolarHBondContact O-CB 3.25Å; V260-Y264 PolarHBondContact O-N 3.18Å
261	T	96.7	Very high	95.2	Very high	15 Å²	15	29.6 Å²	29.6	9%	0.092	15%	0.152	C	C	.	.	H	α-helix	trans	-61.5	-43.8	176.4	-56.1	0	0	0	0	111.9	G70 Y229 C257 L258 L259 T265	G70-T261 VanDerWaalsContact CA-OG1 3.28Å; G70-T261 WeakPolarHBondContact CA-OG1 3.17Å; Y229-T261 WeakPolarHBondContact CE1-OG1 3.27Å; Y229-T261 WeakPolarHBondContact OH-CA 3.2Å; C257-T261 VanDerWaalsContact O-CB 3.3Å; C257-T261 WeakPolarHBondContact O-CB 3.32Å; C257-T261 PolarHBondContact O-N 2.94Å; C257-T261 PolarHBondContact O-OG1 2.95Å; L258-T261 PolarHBondContact O-N 2.89Å; L259-T261 VanDerWaalsContact C-N 3.32Å; L259-T261 PolarHBondContact O-N 3.35Å; T261-T265 VanDerWaalsContact O-CB 3.3Å; T261-T265 WeakPolarHBondContact O-CB 3.27Å; T261-T265 PolarHBondContact O-N 2.92Å; T261-T265 PolarHBondContact O-OG1 2.79Å
262	F	96.3	Very high	95.1	Very high	113 Å²	113	27.1 Å²	27.1	50%	0.496	14%	0.139	S	C	.	.	H	α-helix	trans	-61.1	-50.2	174.6	178.5	-99.9	0	0	0	111.5	L258 L259 V260 Y264 T265 M266	L258-F262 WeakPolarHBondContact O-CB 3.46Å; L258-F262 PolarHBondContact O-N 3.34Å; L259-F262 PolarHBondContact O-N 2.97Å; V260-F262 VanDerWaalsContact C-N 3.34Å; V260-F262 PolarHBondContact O-N 3.38Å; F262-Y264 PolarHBondContact O-N 3.48Å; F262-T265 PolarHBondContact O-N 3.15Å; F262-M266 HydrophobicContact CD1-CG 4.22Å; F262-M266 HydrophobicContact CD2-CG 4.06Å; F262-M266 HydrophobicContact CE1-CG 3.88Å; F262-M266 HydrophobicContact CE2-CE 4.41Å; F262-M266 HydrophobicContact CE2-CG 3.7Å; F262-M266 HydrophobicContact CE2-SD 4.08Å; F262-M266 HydrophobicContact CG-CG 4.31Å; F262-M266 HydrophobicContact CZ-CG 3.61Å; F262-M266 HydrophobicContact CZ-SD 4.19Å; F262-M266 WeakPolarHBondContact O-CB 3.45Å; F262-M266 VanDerWaalsContact O-CG 3.23Å; F262-M266 WeakPolarHBondContact O-CG 3.41Å; F262-M266 PolarHBondContact O-N 3.45Å
263	I	95.1	Very high	95.1	Very high	28 Å²	28	27.8 Å²	27.8	14%	0.144	14%	0.143	C	C	.	.	H	α-helix	trans	-58.6	-48.5	-179.9	-71.1	168.8	0	0	0	111.1	I41 L185 I189 L259 V260 M266 A267	I41-I263 HydrophobicContact CD1-CD1 3.86Å; I41-I263 HydrophobicContact CD1-CG2 4.37Å; L185-I263 HydrophobicContact CB-CG2 4.3Å; L185-I263 HydrophobicContact CD1-CG2 3.91Å; I189-I263 HydrophobicContact CD1-CB 4.36Å; I189-I263 HydrophobicContact CD1-CG1 4.49Å; I189-I263 HydrophobicContact CD1-CG2 3.94Å; L259-I263 HydrophobicContact CD1-CD1 3.93Å; L259-I263 HydrophobicContact CD1-CG1 4.29Å; L259-I263 HydrophobicContact CG-CD1 3.86Å; L259-I263 VanDerWaalsContact O-CG1 3.28Å; L259-I263 WeakPolarHBondContact O-CG1 3.49Å; L259-I263 PolarHBondContact O-N 3.35Å; V260-I263 PolarHBondContact O-N 3.46Å; I263-M266 PolarHBondContact O-N 3.45Å; I263-A267 VanDerWaalsContact O-CB 3.31Å; I263-A267 WeakPolarHBondContact O-CB 3.4Å; I263-A267 PolarHBondContact O-N 3.01Å
264	Y	95.7	Very high	95.1	Very high	0 Å²	0	29 Å²	29	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-65.8	-43.2	-179.3	-71.5	-7.8	0	0	0	112.1	M40 I41 I45 W66 A228 Y229 V260 F262 A267 N268	M40-Y264 PolarHBondContact O-OH 3.5Å; I41-Y264 WeakPolarHBondContact CA-OH 3.47Å; I41-Y264 HydrophobicContact CG1-CE1 4.14Å; I45-Y264 HydrophobicContact CB-CD1 3.94Å; I45-Y264 HydrophobicContact CB-CE1 3.64Å; I45-Y264 HydrophobicContact CD1-CD1 3.65Å; I45-Y264 HydrophobicContact CD1-CE1 4.26Å; I45-Y264 HydrophobicContact CD1-CG 3.86Å; I45-Y264 HydrophobicContact CG1-CD1 3.7Å; I45-Y264 HydrophobicContact CG1-CE1 3.94Å; I45-Y264 HydrophobicContact CG1-CG 4.41Å; I45-Y264 HydrophobicContact CG2-CE1 4.18Å; W66-Y264 AromaticContact CE3-CD2 3.8Å; W66-Y264 HydrophobicContact CE3-CD2 3.8Å; W66-Y264 HydrophobicContact CE3-CG 4.12Å; W66-Y264 HydrophobicContact CH2-CD2 4.35Å; W66-Y264 AromaticContact CZ3-CD2 3.34Å; W66-Y264 HydrophobicContact CZ3-CD2 3.34Å; W66-Y264 AromaticContact CZ3-CE2 3.97Å; W66-Y264 HydrophobicContact CZ3-CE2 3.97Å; W66-Y264 AromaticContact CZ3-CG 3.78Å; W66-Y264 HydrophobicContact CZ3-CG 3.78Å; A228-Y264 HydrophobicContact CB-CE2 3.91Å; A228-Y264 VanDerWaalsContact O-CE2 3.22Å; A228-Y264 WeakPolarHBondContact O-CE2 3.44Å; A228-Y264 PolarHBondContact O-OH 3.42Å; Y229-Y264 HydrophobicContact CD1-CD2 4.37Å; Y229-Y264 HydrophobicContact CD1-CE2 4.31Å; Y229-Y264 HydrophobicContact CD2-CD2 4.35Å; Y229-Y264 HydrophobicContact CD2-CE2 4.42Å; Y229-Y264 AromaticContact CE1-CD2 3.86Å; Y229-Y264 HydrophobicContact CE1-CD2 3.86Å; Y229-Y264 HydrophobicContact CE1-CE2 4.24Å; Y229-Y264 AromaticContact CE2-CD2 3.86Å; Y229-Y264 HydrophobicContact CE2-CD2 3.86Å; Y229-Y264 HydrophobicContact CE2-CE2 4.37Å; Y229-Y264 HydrophobicContact CG-CE2 4.39Å; Y229-Y264 AromaticContact CZ-CD2 3.57Å; V260-Y264 HydrophobicContact CG1-CD1 4.32Å; V260-Y264 HydrophobicContact CG1-CD2 3.69Å; V260-Y264 HydrophobicContact CG1-CE1 4.08Å; V260-Y264 HydrophobicContact CG1-CE2 3.42Å; V260-Y264 VanDerWaalsContact CG1-CE2 3.42Å; V260-Y264 HydrophobicContact CG1-CG 4.16Å; V260-Y264 WeakPolarHBondContact O-CB 3.25Å; V260-Y264 PolarHBondContact O-N 3.18Å; F262-Y264 PolarHBondContact O-N 3.48Å; Y264-A267 PolarHBondContact O-N 3.44Å; Y264-N268 PolarHBondContact O-N 2.73Å; Y264-N268 PolarHBondContact O-ND2 3.33Å
265	T	96.1	Very high	95	Very high	20 Å²	20	26.2 Å²	26.2	12%	0.123	14%	0.137	C	C	.	.	H	α-helix	trans	-63.4	-46.2	177.5	-51.7	0	0	0	0	110.5	L63 V67 T261 F262 A267 N268 V269	L63-T265 HydrophobicContact CD2-CG2 4.18Å; V67-T265 HydrophobicContact CG2-CG2 4.21Å; T261-T265 VanDerWaalsContact O-CB 3.3Å; T261-T265 WeakPolarHBondContact O-CB 3.27Å; T261-T265 PolarHBondContact O-N 2.92Å; T261-T265 PolarHBondContact O-OG1 2.79Å; F262-T265 PolarHBondContact O-N 3.15Å; T265-A267 PolarHBondContact O-N 2.75Å; T265-N268 PolarHBondContact O-N 3.41Å; T265-V269 WeakPolarHBondContact O-CG2 3.22Å; T265-V269 PolarHBondContact O-N 3.24Å
266	M	95.6	Very high	94.7	Very high	45 Å²	45	25.4 Å²	25.4	22%	0.222	14%	0.137	C	C	.	.	H	α-helix	trans	-64.8	-37.1	178.4	-69.8	-60	103.4	0	0	112.8	I189 F193 F262 I263 N268 V269 A270	I189-M266 HydrophobicContact CD1-CB 4.2Å; I189-M266 HydrophobicContact CG1-CB 4.07Å; I189-M266 HydrophobicContact CG2-CB 4.21Å; F193-M266 HydrophobicContact CZ-SD 3.97Å; F262-M266 HydrophobicContact CD1-CG 4.22Å; F262-M266 HydrophobicContact CD2-CG 4.06Å; F262-M266 HydrophobicContact CE1-CG 3.88Å; F262-M266 HydrophobicContact CE2-CE 4.41Å; F262-M266 HydrophobicContact CE2-CG 3.7Å; F262-M266 HydrophobicContact CE2-SD 4.08Å; F262-M266 HydrophobicContact CG-CG 4.31Å; F262-M266 HydrophobicContact CZ-CG 3.61Å; F262-M266 HydrophobicContact CZ-SD 4.19Å; F262-M266 WeakPolarHBondContact O-CB 3.45Å; F262-M266 VanDerWaalsContact O-CG 3.23Å; F262-M266 WeakPolarHBondContact O-CG 3.41Å; F262-M266 PolarHBondContact O-N 3.45Å; I263-M266 PolarHBondContact O-N 3.45Å; M266-N268 VanDerWaalsContact C-N 3.35Å; M266-V269 HydrophobicContact CE-CG2 4.45Å; M266-V269 PolarHBondContact O-N 3.43Å; M266-A270 WeakPolarHBondContact O-CB 3.31Å; M266-A270 PolarHBondContact O-N 3.07Å
267	A	95.1	Very high	94.5	Very high	0 Å²	0	27.7 Å²	27.7	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-64.2	-40.3	174.9	0	0	0	0	0	111.7	I45 L185 I188 I189 I263 Y264 T265 A270 Y271	I45-A267 HydrophobicContact CD1-CB 4.4Å; I45-A267 HydrophobicContact CG1-CB 4.45Å; L185-A267 HydrophobicContact CD2-CB 4.28Å; I188-A267 HydrophobicContact CG2-CB 4.37Å; I189-A267 HydrophobicContact CG1-CB 4.34Å; I263-A267 VanDerWaalsContact O-CB 3.31Å; I263-A267 WeakPolarHBondContact O-CB 3.4Å; I263-A267 PolarHBondContact O-N 3.01Å; Y264-A267 PolarHBondContact O-N 3.44Å; T265-A267 PolarHBondContact O-N 2.75Å; A267-A270 WeakPolarHBondContact O-CB 3.43Å; A267-A270 PolarHBondContact O-N 3.03Å; A267-Y271 WeakPolarHBondContact O-CD2 3.39Å; A267-Y271 PolarHBondContact O-N 3.48Å
268	N	95.1	Very high	94.2	Very high	9 Å²	9	34.1 Å²	34.1	5%	0.048	18%	0.182	C	C	.	.	H	α-helix	trans	-68.5	-38.6	175.6	-77.4	-87.1	0	0	0	112.2	P49 L63 W66 Y264 T265 M266 A270 Y271 V272	P49-N268 WeakPolarHBondContact CB-OD1 3.33Å; L63-N268 HydrophobicContact CD2-CB 3.78Å; W66-N268 WeakPolarHBondContact CZ2-ND2 3.15Å; W66-N268 VanDerWaalsContact NE1-CG 3.25Å; W66-N268 PolarHBondContact NE1-ND2 2.74Å; W66-N268 VanDerWaalsContact NE1-ND2 3.12Å; W66-N268 PolarHBondContact NE1-OD1 3.5Å; Y264-N268 PolarHBondContact O-N 2.73Å; Y264-N268 PolarHBondContact O-ND2 3.33Å; T265-N268 PolarHBondContact O-N 3.41Å; M266-N268 VanDerWaalsContact C-N 3.35Å; N268-A270 VanDerWaalsContact C-N 3.3Å; N268-A270 PolarHBondContact O-N 3.09Å; N268-Y271 PolarHBondContact O-N 3.35Å; N268-V272 PolarHBondContact O-N 3.43Å
269	V	95.2	Very high	93.8	Very high	24 Å²	24	32 Å²	32	15%	0.145	17%	0.17	C	C	.	.	H	α-helix	trans	-60.4	-42.3	170.7	173	0	0	0	0	110.6	L63 I196 T265 M266 Y271 V272 T273	L63-V269 HydrophobicContact CD1-CG2 4.06Å; L63-V269 HydrophobicContact CD2-CG2 3.94Å; I196-V269 HydrophobicContact CD1-CG1 4.09Å; T265-V269 WeakPolarHBondContact O-CG2 3.22Å; T265-V269 PolarHBondContact O-N 3.24Å; M266-V269 HydrophobicContact CE-CG2 4.45Å; M266-V269 PolarHBondContact O-N 3.43Å; V269-Y271 PolarHBondContact O-N 2.85Å; V269-V272 WeakPolarHBondContact O-CG2 3.49Å; V269-V272 PolarHBondContact O-N 3.27Å; V269-T273 WeakPolarHBondContact O-CG2 3.46Å; V269-T273 PolarHBondContact O-N 2.93Å
270	A	95.4	Very high	93.6	Very high	2 Å²	2	29 Å²	29	2%	0.017	15%	0.154	C	C	.	.	H	α-helix	trans	-61.6	-43.2	175.9	0	0	0	0	0	111.9	I188 M266 A267 N268 V272 T273 F290	I188-A270 HydrophobicContact CG2-CB 3.79Å; I188-A270 WeakPolarHBondContact O-CB 3.49Å; M266-A270 WeakPolarHBondContact O-CB 3.31Å; M266-A270 PolarHBondContact O-N 3.07Å; A267-A270 WeakPolarHBondContact O-CB 3.43Å; A267-A270 PolarHBondContact O-N 3.03Å; N268-A270 VanDerWaalsContact C-N 3.3Å; N268-A270 PolarHBondContact O-N 3.09Å; A270-V272 VanDerWaalsContact C-N 3.32Å; A270-V272 PolarHBondContact O-N 2.79Å; A270-T273 PolarHBondContact O-N 2.99Å; A270-T273 PolarHBondContact O-OG1 3.29Å; A270-F290 WeakPolarHBondContact O-CE2 3.14Å
271	Y	94.5	Very high	93.3	Very high	1 Å²	1	31.6 Å²	31.6	0%	0.004	17%	0.168	C	C	.	.	H	α-helix	trans	-56.7	-44.5	177.8	-68.7	-39.2	0	0	0	112.5	P49 I188 A267 N268 V269 T273 V274 V275 V286 A287 F290	P49-Y271 HydrophobicContact CB-CD2 4.45Å; P49-Y271 HydrophobicContact CG-CD2 4.28Å; P49-Y271 HydrophobicContact CG-CE2 3.92Å; I188-Y271 HydrophobicContact CD1-CE1 3.98Å; I188-Y271 HydrophobicContact CG1-CE1 4.48Å; I188-Y271 HydrophobicContact CG2-CD1 4.28Å; I188-Y271 HydrophobicContact CG2-CE1 3.93Å; A267-Y271 WeakPolarHBondContact O-CD2 3.39Å; A267-Y271 PolarHBondContact O-N 3.48Å; N268-Y271 PolarHBondContact O-N 3.35Å; V269-Y271 PolarHBondContact O-N 2.85Å; Y271-T273 VanDerWaalsContact C-N 3.26Å; Y271-T273 PolarHBondContact O-N 2.69Å; Y271-V274 PolarHBondContact O-N 3.5Å; Y271-V275 WeakPolarHBondContact O-CB 3.37Å; Y271-V275 PolarHBondContact O-N 2.81Å; Y271-V286 HydrophobicContact CD1-CG1 3.85Å; Y271-V286 HydrophobicContact CD2-CG1 3.93Å; Y271-V286 HydrophobicContact CE1-CG1 4.22Å; Y271-V286 HydrophobicContact CE2-CG1 4.3Å; Y271-V286 HydrophobicContact CG-CG1 3.71Å; Y271-A287 HydrophobicContact CE1-CB 4.21Å; Y271-F290 HydrophobicContact CD1-CB 4.08Å; Y271-F290 AromaticContact CD1-CD2 3.87Å; Y271-F290 HydrophobicContact CD1-CD2 3.87Å; Y271-F290 HydrophobicContact CD1-CG 4.08Å; Y271-F290 HydrophobicContact CE1-CB 4.28Å; Y271-F290 HydrophobicContact CE1-CG 4.37Å
272	V	93.6	Very high	92.7	Very high	11 Å²	11	35.4 Å²	35.4	7%	0.067	19%	0.191	C	C	.	.	H	α-helix	trans	-73.7	-13.7	-176.9	-58.9	0	0	0	0	114.4	I59 L204 N268 V269 A270 V274 I280	I59-V272 HydrophobicContact CD1-CB 4.09Å; I59-V272 HydrophobicContact CD1-CG1 3.69Å; I59-V272 HydrophobicContact CG1-CG1 3.96Å; I59-V272 HydrophobicContact CG2-CB 4.47Å; I59-V272 HydrophobicContact CG2-CG1 3.86Å; I59-V272 HydrophobicContact CG2-CG2 4.34Å; L204-V272 HydrophobicContact CD2-CG2 3.67Å; L204-V272 HydrophobicContact CG-CG2 4.15Å; N268-V272 PolarHBondContact O-N 3.43Å; V269-V272 WeakPolarHBondContact O-CG2 3.49Å; V269-V272 PolarHBondContact O-N 3.27Å; A270-V272 VanDerWaalsContact C-N 3.32Å; A270-V272 PolarHBondContact O-N 2.79Å; V272-V274 VanDerWaalsContact C-N 3.26Å; V272-I280 HydrophobicContact CG1-CD1 3.86Å
273	T	93.5	Very high	92.2	Very high	14 Å²	14	30.7 Å²	30.7	9%	0.086	17%	0.171	C	C	.	.	H	α-helix	trans	-76.7	-15.6	173	65	0	0	0	0	112.8	I196 K200 V269 A270 Y271	I196-T273 HydrophobicContact CD1-CG2 4.09Å; I196-T273 HydrophobicContact CG1-CG2 3.6Å; K200-T273 WeakPolarHBondContact O-CB 3.48Å; V269-T273 WeakPolarHBondContact O-CG2 3.46Å; V269-T273 PolarHBondContact O-N 2.93Å; A270-T273 PolarHBondContact O-N 2.99Å; A270-T273 PolarHBondContact O-OG1 3.29Å; Y271-T273 VanDerWaalsContact C-N 3.26Å; Y271-T273 PolarHBondContact O-N 2.69Å
274	V	93	Very high	91.1	Very high	29 Å²	29	31.6 Å²	31.6	18%	0.176	18%	0.179	C	C	.	.	H	α-helix	trans	-124.1	-42.7	-172.9	175.4	0	0	0	0	112	Q195 Y271 V272 F290 R293 I294	Q195-V274 HydrophobicContact CG-CG2 3.82Å; Y271-V274 PolarHBondContact O-N 3.5Å; V272-V274 VanDerWaalsContact C-N 3.26Å; V274-F290 HydrophobicContact CB-CD2 3.6Å; V274-F290 HydrophobicContact CB-CE2 3.73Å; V274-F290 HydrophobicContact CG1-CD2 3.87Å; V274-F290 HydrophobicContact CG1-CE2 4.26Å; V274-F290 HydrophobicContact CG1-CG 4.43Å; V274-F290 HydrophobicContact CG2-CD2 3.83Å; V274-F290 HydrophobicContact CG2-CE2 3.38Å; V274-F290 HydrophobicContact CG2-CZ 4.16Å; V274-R293 HydrophobicContact CG1-CB 3.59Å; V274-R293 HydrophobicContact CG1-CG 4.25Å; V274-I294 HydrophobicContact CB-CG1 4.37Å; V274-I294 HydrophobicContact CG1-CD1 3.92Å; V274-I294 HydrophobicContact CG1-CG1 3.58Å; V274-I294 HydrophobicContact CG2-CD1 3.84Å; V274-I294 HydrophobicContact CG2-CG1 3.8Å
275	V	92.5	Very high	90.6	Very high	1 Å²	1	31.6 Å²	31.6	1%	0.006	18%	0.179	C	C	.	.	S	Bend	trans	-106.3	128	-175.6	-171.2	0	0	0	0	108.4	Y271 E279 I280 T289 F290	Y271-V275 WeakPolarHBondContact O-CB 3.37Å; Y271-V275 PolarHBondContact O-N 2.81Å; V275-E279 HydrophobicContact CG1-CB 3.8Å; V275-E279 HydrophobicContact CG1-CG 3.93Å; V275-I280 HydrophobicContact CB-CG1 4.13Å; V275-I280 HydrophobicContact CG1-CG1 3.75Å; V275-T289 HydrophobicContact CG1-CG2 3.93Å; V275-T289 HydrophobicContact CG2-CG2 4.2Å; V275-F290 HydrophobicContact CG2-CB 3.99Å; V275-F290 HydrophobicContact CG2-CD2 4.45Å
276	S	90.7	Very high	90.3	Very high	57 Å²	57	30.7 Å²	30.7	40%	0.399	17%	0.174	S	C	.	.			trans	-67.9	151	-179.8	71.5	0	0	0	0	111.6	H278 E279 I280	S276-H278 PolarHBondContact O-N 3.42Å; S276-E279 PolarHBondContact O-N 3.24Å; S276-E279 WeakPolarHBondContact OG-CB 3.42Å; S276-E279 PolarHBondContact OG-N 3.04Å; S276-I280 PolarHBondContact O-N 3.05Å
277	P	88.3	Confident	90.1	Very high	48 Å²	48	28.6 Å²	28.6	31%	0.312	16%	0.163	S	C	.	.	H	α-helix	trans	-53.6	-37.9	177.6	2.2	-13.2	0	0	0	114	I59 I280 L281	I59-P277 HydrophobicContact CD1-CB 3.71Å; I59-P277 HydrophobicContact CD1-CG 3.61Å; I59-P277 HydrophobicContact CG1-CB 4.16Å; P277-I280 PolarHBondContact O-N 3.38Å; P277-L281 PolarHBondContact O-N 3.26Å
278	H	88.4	Confident	89.8	Confident	136 Å²	136	28.9 Å²	28.9	63%	0.63	17%	0.165	S	C	*	.	H	α-helix	trans	-66.3	-39	177	-171.6	-10.1	0	0	0	112.1	S276 L281 T282	S276-H278 PolarHBondContact O-N 3.42Å; H278-L281 PolarHBondContact O-N 2.76Å; H278-T282 PolarHBondContact O-N 3.27Å; H278-T282 PolarHBondContact O-OG1 3.5Å; H278-T282 VanDerWaalsContact O-OG1 3.12Å
279	E	89.2	Confident	89.5	Confident	47 Å²	47	29.3 Å²	29.3	22%	0.22	17%	0.168	C	C	.	.	H	α-helix	trans	-70.6	-34.7	179.1	-165.2	174.8	-164.9	0	0	111.1	V275 S276 L281 T282 T283 T289 R293	V275-E279 HydrophobicContact CG1-CB 3.8Å; V275-E279 HydrophobicContact CG1-CG 3.93Å; S276-E279 PolarHBondContact O-N 3.24Å; S276-E279 WeakPolarHBondContact OG-CB 3.42Å; S276-E279 PolarHBondContact OG-N 3.04Å; E279-L281 VanDerWaalsContact C-N 3.27Å; E279-L281 PolarHBondContact O-N 3.02Å; E279-T282 WeakPolarHBondContact CA-OG1 3.5Å; E279-T282 PolarHBondContact O-N 3.44Å; E279-T282 PolarHBondContact O-OG1 3.25Å; E279-T283 WeakPolarHBondContact O-CB 3.42Å; E279-T283 WeakPolarHBondContact O-CG2 3.37Å; E279-T283 PolarHBondContact O-N 3.04Å; E279-T289 HydrophobicContact CG-CG2 3.9Å; E279-T289 WeakPolarHBondContact OE1-CG2 3.13Å; E279-R293 IonicContact OE1-CZ 3.3Å; E279-R293 IonicContact OE1-NE 2.76Å; E279-R293 IonicContact OE1-NH2 3.56Å; E279-R293 PolarHBondContact OE1-NH2 3.38Å; E279-R293 IonicContact OE2-NH2 2.64Å; E279-R293 PolarHBondContact OE2-NH2 3.17Å
280	I	90.5	Very high	89.4	Confident	8 Å²	8	28.2 Å²	28.2	4%	0.041	16%	0.161	C	C	.	.	H	α-helix	trans	-58.6	-38.8	172.5	-67.6	172	0	0	0	111.8	T50 M53 V272 V275 S276 P277 T282 V286	T50-I280 VanDerWaalsContact CG2-O 3.31Å; T50-I280 WeakPolarHBondContact CG2-O 3.41Å; T50-I280 PolarHBondContact OG1-O 3.29Å; M53-I280 HydrophobicContact CB-CG2 4.15Å; M53-I280 HydrophobicContact CG-CG2 4.14Å; V272-I280 HydrophobicContact CG1-CD1 3.86Å; V275-I280 HydrophobicContact CB-CG1 4.13Å; V275-I280 HydrophobicContact CG1-CG1 3.75Å; S276-I280 PolarHBondContact O-N 3.05Å; P277-I280 PolarHBondContact O-N 3.38Å; I280-T282 VanDerWaalsContact C-N 3.33Å; I280-V286 HydrophobicContact CG1-CG1 4.26Å; I280-V286 HydrophobicContact CG2-CG2 4.18Å
281	L	88.1	Confident	89.3	Confident	56 Å²	56	28.1 Å²	28.1	29%	0.293	16%	0.16	S	C	.	.	H	α-helix	trans	-72.7	-24	-179.9	-72.3	172.8	0	0	0	113.8	M53 E54 P277 H278 E279	M53-L281 VanDerWaalsContact C-CD2 3.49Å; M53-L281 HydrophobicContact CB-CD2 3.97Å; M53-L281 HydrophobicContact CG-CD2 3.69Å; M53-L281 HydrophobicContact CG-CG 4.04Å; E54-L281 VanDerWaalsContact CA-CD2 3.46Å; E54-L281 HydrophobicContact CB-CD2 4.05Å; P277-L281 PolarHBondContact O-N 3.26Å; H278-L281 PolarHBondContact O-N 2.76Å; E279-L281 VanDerWaalsContact C-N 3.27Å; E279-L281 PolarHBondContact O-N 3.02Å
282	T	85.5	Confident	89.1	Confident	94 Å²	94	31.7 Å²	31.7	58%	0.577	18%	0.182	S	C	*	.	H	α-helix	trans	-102.7	-24.7	-174.4	49.4	0	0	0	0	112.6	H278 E279 I280	H278-T282 PolarHBondContact O-N 3.27Å; H278-T282 PolarHBondContact O-OG1 3.5Å; H278-T282 VanDerWaalsContact O-OG1 3.12Å; E279-T282 WeakPolarHBondContact CA-OG1 3.5Å; E279-T282 PolarHBondContact O-N 3.44Å; E279-T282 PolarHBondContact O-OG1 3.25Å; I280-T282 VanDerWaalsContact C-N 3.33Å
283	T	84.3	Confident	88.9	Confident	15 Å²	15	38.5 Å²	38.5	9%	0.092	21%	0.206	C	C	.	.			trans	-85.5	129.3	-179.9	-169.6	0	0	0	0	112.2	T50 E279 A285 V286 T289	T50-T283 PolarHBondContact OG1-O 2.97Å; E279-T283 WeakPolarHBondContact O-CB 3.42Å; E279-T283 WeakPolarHBondContact O-CG2 3.37Å; E279-T283 PolarHBondContact O-N 3.04Å; T283-A285 PolarHBondContact O-N 2.92Å; T283-A285 PolarHBondContact OG1-N 3.08Å; T283-V286 HydrophobicContact CG2-CB 4.29Å; T283-V286 HydrophobicContact CG2-CG2 3.73Å; T283-T289 WeakPolarHBondContact CB-OG1 3.29Å; T283-T289 PolarHBondContact OG1-OG1 3.44Å
284	P	73.2	Confident	88.9	Confident	46 Å²	46	40.4 Å²	40.4	30%	0.299	22%	0.216	S	C	.	.	S	Bend	trans	-74.9	-9.9	172.2	30.9	-34.8	0	0	0	112.9	K131	K131-P284 HydrophobicContact CD-CB 4.41Å
285	A	84.9	Confident	88.7	Confident	1 Å²	1	41.3 Å²	41.3	1%	0.008	22%	0.216	C	C	.	.			trans	-139.5	74.8	-173.8	0	0	0	0	0	111.9	Y132 T283 A287 I288 T289	Y132-A285 HydrophobicContact CD1-CB 4.28Å; Y132-A285 HydrophobicContact CD2-CB 4.42Å; Y132-A285 HydrophobicContact CE1-CB 3.83Å; Y132-A285 HydrophobicContact CE2-CB 4Å; Y132-A285 WeakPolarHBondContact OH-CA 3.49Å; T283-A285 PolarHBondContact O-N 2.92Å; T283-A285 PolarHBondContact OG1-N 3.08Å; A285-A287 VanDerWaalsContact C-N 3.27Å; A285-A287 PolarHBondContact O-N 3.28Å; A285-I288 HydrophobicContact CB-CB 4.16Å; A285-I288 HydrophobicContact CB-CD1 3.79Å; A285-I288 HydrophobicContact CB-CG1 4.01Å; A285-I288 PolarHBondContact O-N 3.42Å; A285-T289 PolarHBondContact O-N 2.83Å; A285-T289 VanDerWaalsContact O-N 3.14Å; A285-T289 PolarHBondContact O-OG1 3.36Å
286	V	89.6	Confident	88.6	Confident	1 Å²	1	43.5 Å²	43.5	1%	0.006	24%	0.239	C	C	.	.	H	α-helix	trans	-54.5	-41.7	-175.4	-178.1	0	0	0	0	112.4	T50 Y271 I280 T283 I288 T289 F290	T50-V286 WeakPolarHBondContact OG1-CG2 3.49Å; Y271-V286 HydrophobicContact CD1-CG1 3.85Å; Y271-V286 HydrophobicContact CD2-CG1 3.93Å; Y271-V286 HydrophobicContact CE1-CG1 4.22Å; Y271-V286 HydrophobicContact CE2-CG1 4.3Å; Y271-V286 HydrophobicContact CG-CG1 3.71Å; I280-V286 HydrophobicContact CG1-CG1 4.26Å; I280-V286 HydrophobicContact CG2-CG2 4.18Å; T283-V286 HydrophobicContact CG2-CB 4.29Å; T283-V286 HydrophobicContact CG2-CG2 3.73Å; V286-I288 VanDerWaalsContact C-N 3.3Å; V286-I288 PolarHBondContact O-N 2.87Å; V286-T289 WeakPolarHBondContact O-CB 3.37Å; V286-T289 PolarHBondContact O-N 3.24Å; V286-F290 WeakPolarHBondContact O-CB 3.29Å; V286-F290 PolarHBondContact O-N 3.46Å
287	A	90.8	Very high	88.4	Confident	0 Å²	0	46.9 Å²	46.9	0%	0	26%	0.257	C	S	.	.	H	α-helix	trans	-64.6	-32	179.6	0	0	0	0	0	113.5	F46 Y132 I188 Y271 A285 S291 M302 V306	F46-A287 HydrophobicContact CD1-CB 3.87Å; F46-A287 HydrophobicContact CE1-CB 4.22Å; Y132-A287 HydrophobicContact CE1-CB 4.19Å; I188-A287 HydrophobicContact CD1-CB 4.41Å; Y271-A287 HydrophobicContact CE1-CB 4.21Å; A285-A287 VanDerWaalsContact C-N 3.27Å; A285-A287 PolarHBondContact O-N 3.28Å; A287-S291 PolarHBondContact O-N 3.19Å; A287-M302 HydrophobicContact CB-CG 3.96Å; A287-M302 HydrophobicContact CB-SD 4.46Å; A287-M302 WeakPolarHBondContact O-CG 3.46Å; A287-V306 HydrophobicContact CB-CG2 4.15Å
288	I	89.2	Confident	88.3	Confident	6 Å²	6	50.1 Å²	50.1	3%	0.031	27%	0.269	C	S	.	.	H	α-helix	trans	-72.2	-44.3	175.1	-60.2	-179.9	0	0	0	109.5	Y132 Q135 A285 V286 F290 S291 V292 W299 P303	Y132-I288 HydrophobicContact CD1-CD1 3.55Å; Y132-I288 HydrophobicContact CD1-CG1 3.7Å; Y132-I288 HydrophobicContact CE1-CD1 4.04Å; Y132-I288 HydrophobicContact CE1-CG1 3.77Å; Y132-I288 HydrophobicContact CG-CD1 4.22Å; Q135-I288 HydrophobicContact CB-CD1 3.54Å; Q135-I288 HydrophobicContact CG-CD1 3.84Å; Q135-I288 HydrophobicContact CG-CG2 4.19Å; A285-I288 HydrophobicContact CB-CB 4.16Å; A285-I288 HydrophobicContact CB-CD1 3.79Å; A285-I288 HydrophobicContact CB-CG1 4.01Å; A285-I288 PolarHBondContact O-N 3.42Å; V286-I288 VanDerWaalsContact C-N 3.3Å; V286-I288 PolarHBondContact O-N 2.87Å; I288-F290 VanDerWaalsContact C-N 3.26Å; I288-F290 PolarHBondContact O-N 3.41Å; I288-S291 PolarHBondContact O-N 3.37Å; I288-S291 PolarHBondContact O-OG 2.98Å; I288-V292 HydrophobicContact CG2-CG2 4.23Å; I288-V292 WeakPolarHBondContact O-CG2 3.4Å; I288-V292 PolarHBondContact O-N 3.29Å; I288-W299 HydrophobicContact CG2-CE3 4.29Å; I288-W299 HydrophobicContact CG2-CZ3 4.16Å; I288-P303 HydrophobicContact CD1-CB 3.71Å; I288-P303 HydrophobicContact CD1-CG 3.94Å; I288-P303 HydrophobicContact CG1-CB 4.01Å; I288-P303 HydrophobicContact CG1-CG 3.9Å; I288-P303 HydrophobicContact CG2-CG 4.28Å
289	T	90	Very high	88.3	Confident	19 Å²	19	47.2 Å²	47.2	12%	0.117	25%	0.253	C	S	.	.	H	α-helix	trans	-57.2	-44.5	176.1	-50.6	0	0	0	0	110.9	V275 E279 T283 A285 V286 S291 V292 R293	V275-T289 HydrophobicContact CG1-CG2 3.93Å; V275-T289 HydrophobicContact CG2-CG2 4.2Å; E279-T289 HydrophobicContact CG-CG2 3.9Å; E279-T289 WeakPolarHBondContact OE1-CG2 3.13Å; T283-T289 WeakPolarHBondContact CB-OG1 3.29Å; T283-T289 PolarHBondContact OG1-OG1 3.44Å; A285-T289 PolarHBondContact O-N 2.83Å; A285-T289 VanDerWaalsContact O-N 3.14Å; A285-T289 PolarHBondContact O-OG1 3.36Å; V286-T289 WeakPolarHBondContact O-CB 3.37Å; V286-T289 PolarHBondContact O-N 3.24Å; T289-S291 PolarHBondContact O-N 2.78Å; T289-V292 PolarHBondContact O-N 3.05Å; T289-R293 VanDerWaalsContact O-CG 3.28Å; T289-R293 WeakPolarHBondContact O-CG 3.35Å; T289-R293 PolarHBondContact O-N 2.91Å
290	F	92.7	Very high	88.1	Confident	0 Å²	0	51.4 Å²	51.4	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-57.2	-46	172.8	179.1	-87.4	0	0	0	112.4	I188 T191 A270 Y271 V274 V275 V286 I288 R293 I294 Y295	I188-F290 HydrophobicContact CG1-CD1 4.39Å; I188-F290 HydrophobicContact CG1-CE1 4.22Å; I188-F290 HydrophobicContact CG2-CE1 4.47Å; I188-F290 HydrophobicContact CG2-CZ 4.33Å; T191-F290 HydrophobicContact CG2-CE1 3.91Å; T191-F290 HydrophobicContact CG2-CZ 3.52Å; A270-F290 WeakPolarHBondContact O-CE2 3.14Å; Y271-F290 HydrophobicContact CD1-CB 4.08Å; Y271-F290 AromaticContact CD1-CD2 3.87Å; Y271-F290 HydrophobicContact CD1-CD2 3.87Å; Y271-F290 HydrophobicContact CD1-CG 4.08Å; Y271-F290 HydrophobicContact CE1-CB 4.28Å; Y271-F290 HydrophobicContact CE1-CG 4.37Å; V274-F290 HydrophobicContact CB-CD2 3.6Å; V274-F290 HydrophobicContact CB-CE2 3.73Å; V274-F290 HydrophobicContact CG1-CD2 3.87Å; V274-F290 HydrophobicContact CG1-CE2 4.26Å; V274-F290 HydrophobicContact CG1-CG 4.43Å; V274-F290 HydrophobicContact CG2-CD2 3.83Å; V274-F290 HydrophobicContact CG2-CE2 3.38Å; V274-F290 HydrophobicContact CG2-CZ 4.16Å; V275-F290 HydrophobicContact CG2-CB 3.99Å; V275-F290 HydrophobicContact CG2-CD2 4.45Å; V286-F290 WeakPolarHBondContact O-CB 3.29Å; V286-F290 PolarHBondContact O-N 3.46Å; I288-F290 VanDerWaalsContact C-N 3.26Å; I288-F290 PolarHBondContact O-N 3.41Å; F290-R293 PolarHBondContact O-N 2.96Å; F290-I294 PolarHBondContact O-N 3.47Å; F290-Y295 HydrophobicContact CE1-CE2 4.47Å
291	S	91.8	Very high	87.9	Confident	0 Å²	0	52.5 Å²	52.5	0%	0	27%	0.272	C	S	.	.	H	α-helix	trans	-69.6	-37.7	-177.5	73.5	0	0	0	0	113.2	A287 I288 T289 R293 I294 Y295 W299 M302	A287-S291 PolarHBondContact O-N 3.19Å; I288-S291 PolarHBondContact O-N 3.37Å; I288-S291 PolarHBondContact O-OG 2.98Å; T289-S291 PolarHBondContact O-N 2.78Å; S291-R293 VanDerWaalsContact C-N 3.27Å; S291-R293 PolarHBondContact O-N 3.3Å; S291-I294 PolarHBondContact O-N 3.07Å; S291-Y295 PolarHBondContact O-N 3.37Å; S291-W299 WeakPolarHBondContact CB-O 3.36Å; S291-W299 PolarHBondContact OG-O 2.88Å; S291-M302 WeakPolarHBondContact OG-CB 3.27Å
292	V	90.6	Very high	87.9	Confident	77 Å²	77	49.9 Å²	49.9	47%	0.467	26%	0.258	S	S	.	.	H	α-helix	trans	-60.9	-38.8	176.3	170.3	0	0	0	0	110.9	I288 T289 W299	I288-V292 HydrophobicContact CG2-CG2 4.23Å; I288-V292 WeakPolarHBondContact O-CG2 3.4Å; I288-V292 PolarHBondContact O-N 3.29Å; T289-V292 PolarHBondContact O-N 3.05Å; V292-W299 HydrophobicContact CB-CB 4.49Å; V292-W299 HydrophobicContact CG2-CB 4.05Å; V292-W299 HydrophobicContact CG2-CD2 3.91Å; V292-W299 HydrophobicContact CG2-CE3 3.76Å; V292-W299 HydrophobicContact CG2-CG 4.05Å; V292-W299 HydrophobicContact CG2-CZ3 4.47Å
293	R	90.3	Very high	88	Confident	153 Å²	153	45.6 Å²	45.6	58%	0.577	23%	0.232	S	C	*	.	H	α-helix	trans	-73	-29.9	-179.2	-65.3	-70.9	-174.1	172.8	1.4	113.7	V274 E279 T289 F290 S291	V274-R293 HydrophobicContact CG1-CB 3.59Å; V274-R293 HydrophobicContact CG1-CG 4.25Å; E279-R293 IonicContact OE1-CZ 3.3Å; E279-R293 IonicContact OE1-NE 2.76Å; E279-R293 IonicContact OE1-NH2 3.56Å; E279-R293 PolarHBondContact OE1-NH2 3.38Å; E279-R293 IonicContact OE2-NH2 2.64Å; E279-R293 PolarHBondContact OE2-NH2 3.17Å; T289-R293 VanDerWaalsContact O-CG 3.28Å; T289-R293 WeakPolarHBondContact O-CG 3.35Å; T289-R293 PolarHBondContact O-N 2.91Å; F290-R293 PolarHBondContact O-N 2.96Å; S291-R293 VanDerWaalsContact C-N 3.27Å; S291-R293 PolarHBondContact O-N 3.3Å
294	I	93	Very high	88.1	Confident	55 Å²	55	48.8 Å²	48.8	28%	0.282	25%	0.248	S	C	.	.	H	α-helix	trans	-110.8	-44.5	-170.5	-61.9	-62.6	0	0	0	114.1	T191 Q195 V274 F290 S291 G296	T191-I294 HydrophobicContact CG2-CB 4.37Å; T191-I294 HydrophobicContact CG2-CG1 4.26Å; T191-I294 HydrophobicContact CG2-CG2 3.65Å; Q195-I294 HydrophobicContact CG-CD1 4.32Å; V274-I294 HydrophobicContact CB-CG1 4.37Å; V274-I294 HydrophobicContact CG1-CD1 3.92Å; V274-I294 HydrophobicContact CG1-CG1 3.58Å; V274-I294 HydrophobicContact CG2-CD1 3.84Å; V274-I294 HydrophobicContact CG2-CG1 3.8Å; F290-I294 PolarHBondContact O-N 3.47Å; S291-I294 PolarHBondContact O-N 3.07Å; I294-G296 VanDerWaalsContact C-N 3.31Å; I294-G296 PolarHBondContact O-N 2.87Å
295	Y	90.2	Very high	88.9	Confident	48 Å²	48	49.1 Å²	49.1	19%	0.188	25%	0.245	C	C	.	.	S	Bend	trans	-88.1	2.6	-168.1	-60.2	-39.8	0	0	0	114.1	M187 T191 F290 S291 V297 M298 M302	M187-Y295 HydrophobicContact CG-CE2 4.3Å; M187-Y295 VanDerWaalsContact CG-OH 3.28Å; M187-Y295 WeakPolarHBondContact CG-OH 3.48Å; M187-Y295 PolarHBondContact O-OH 3.5Å; M187-Y295 HydrophobicContact SD-CD2 4.32Å; M187-Y295 HydrophobicContact SD-CE1 4.42Å; M187-Y295 HydrophobicContact SD-CE2 3.52Å; M187-Y295 VanDerWaalsContact SD-CE2 3.52Å; T191-Y295 HydrophobicContact CG2-CE1 4.31Å; T191-Y295 PolarHBondContact OG1-OH 3.28Å; F290-Y295 HydrophobicContact CE1-CE2 4.47Å; S291-Y295 PolarHBondContact O-N 3.37Å; Y295-V297 PolarHBondContact O-N 3.39Å; Y295-M298 PolarHBondContact O-N 3.15Å; Y295-M302 HydrophobicContact CE2-CE 3.8Å
296	G	88.5	Confident	89	Confident	46 Å²	46	49 Å²	49	47%	0.474	24%	0.244	S	C	.	.	G	3₁₀ helix	trans	52.4	-124.2	179.1	0	0	0	0	0	110.5	I294 M298 W299	I294-G296 VanDerWaalsContact C-N 3.31Å; I294-G296 PolarHBondContact O-N 2.87Å; G296-M298 PolarHBondContact O-N 3.41Å; G296-M298 VanDerWaalsContact O-N 3.1Å; G296-W299 WeakPolarHBondContact O-CB 3.27Å; G296-W299 PolarHBondContact O-N 3.14Å; G296-W299 VanDerWaalsContact O-N 3.14Å
297	V	87.1	Confident	89	Confident	129 Å²	129	49.2 Å²	49.2	78%	0.782	25%	0.246	S	C	*	.	G	3₁₀ helix	trans	-60.4	-23	-179.3	-174.7	0	0	0	0	113.4	Y295 W299 W300	Y295-V297 PolarHBondContact O-N 3.39Å; V297-W299 VanDerWaalsContact C-N 3.31Å; V297-W299 PolarHBondContact O-N 2.93Å; V297-W300 PolarHBondContact O-NE1 3.37Å
298	M	86.5	Confident	88.9	Confident	115 Å²	115	51.7 Å²	51.7	57%	0.567	26%	0.259	S	S	*	.	G	3₁₀ helix	trans	-88.9	9.9	-178.9	-61.8	178.4	73.5	0	0	113.5	Y295 G296 W300 I301	Y295-M298 PolarHBondContact O-N 3.15Å; G296-M298 PolarHBondContact O-N 3.41Å; G296-M298 VanDerWaalsContact O-N 3.1Å; M298-W300 PolarHBondContact O-N 3.46Å; M298-W300 VanDerWaalsContact O-N 3.12Å; M298-I301 HydrophobicContact CB-CD1 3.99Å; M298-I301 HydrophobicContact CE-CD1 3.51Å; M298-I301 HydrophobicContact CG-CD1 4.49Å; M298-I301 WeakPolarHBondContact O-CB 3.31Å; M298-I301 WeakPolarHBondContact O-CG1 3.23Å; M298-I301 PolarHBondContact O-N 2.93Å
299	W	87.9	Confident	88.9	Confident	76 Å²	76	51.5 Å²	51.5	29%	0.288	26%	0.258	S	S	.	.	T	Hydrogen-bonded Turn	trans	-56.2	-31.1	-177.6	71.7	-97.6	0	0	0	113.9	P136 I288 S291 V292 G296 V297 I301 M302 P303	P136-W299 HydrophobicContact CB-CH2 3.62Å; P136-W299 HydrophobicContact CB-CZ3 4.14Å; P136-W299 HydrophobicContact CG-CH2 3.95Å; P136-W299 HydrophobicContact CG-CZ3 3.94Å; I288-W299 HydrophobicContact CG2-CE3 4.29Å; I288-W299 HydrophobicContact CG2-CZ3 4.16Å; S291-W299 WeakPolarHBondContact CB-O 3.36Å; S291-W299 PolarHBondContact OG-O 2.88Å; V292-W299 HydrophobicContact CB-CB 4.49Å; V292-W299 HydrophobicContact CG2-CB 4.05Å; V292-W299 HydrophobicContact CG2-CD2 3.91Å; V292-W299 HydrophobicContact CG2-CE3 3.76Å; V292-W299 HydrophobicContact CG2-CG 4.05Å; V292-W299 HydrophobicContact CG2-CZ3 4.47Å; G296-W299 WeakPolarHBondContact O-CB 3.27Å; G296-W299 PolarHBondContact O-N 3.14Å; G296-W299 VanDerWaalsContact O-N 3.14Å; V297-W299 VanDerWaalsContact C-N 3.31Å; V297-W299 PolarHBondContact O-N 2.93Å; W299-I301 PolarHBondContact O-N 3.41Å; W299-M302 PolarHBondContact O-N 2.92Å; W299-P303 HydrophobicContact CE3-CG 4.2Å; W299-P303 HydrophobicContact CZ3-CG 3.96Å; W299-P303 WeakPolarHBondContact O-CD 3.41Å
300	W	85.1	Confident	88.9	Confident	134 Å²	134	50.6 Å²	50.6	51%	0.508	25%	0.252	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67.1	-16.7	-176.7	61	-93.3	0	0	0	114	V297 M298 M302 P303 I304	V297-W300 PolarHBondContact O-NE1 3.37Å; M298-W300 PolarHBondContact O-N 3.46Å; M298-W300 VanDerWaalsContact O-N 3.12Å; W300-M302 VanDerWaalsContact C-N 3.29Å; W300-M302 PolarHBondContact O-N 3.01Å; W300-P303 WeakPolarHBondContact O-CD 3.32Å; W300-I304 HydrophobicContact CE3-CD1 3.49Å; W300-I304 VanDerWaalsContact CE3-CD1 3.49Å; W300-I304 HydrophobicContact CZ3-CD1 3.61Å
301	I	86.1	Confident	88.7	Confident	32 Å²	32	51.7 Å²	51.7	16%	0.164	26%	0.257	C	S	.	.	H	α-helix	trans	-62.9	-38.8	176.7	-64.8	177.5	0	0	0	110.8	M187 M298 W299 I304 F305	M187-I301 HydrophobicContact CE-CG2 4.36Å; M298-I301 HydrophobicContact CB-CD1 3.99Å; M298-I301 HydrophobicContact CE-CD1 3.51Å; M298-I301 HydrophobicContact CG-CD1 4.49Å; M298-I301 WeakPolarHBondContact O-CB 3.31Å; M298-I301 WeakPolarHBondContact O-CG1 3.23Å; M298-I301 PolarHBondContact O-N 2.93Å; W299-I301 PolarHBondContact O-N 3.41Å; I301-I304 PolarHBondContact O-N 2.94Å; I301-F305 HydrophobicContact CG2-CD1 4.38Å; I301-F305 HydrophobicContact CG2-CD2 3.91Å; I301-F305 HydrophobicContact CG2-CE1 4.1Å; I301-F305 HydrophobicContact CG2-CE2 3.59Å; I301-F305 HydrophobicContact CG2-CG 4.3Å; I301-F305 HydrophobicContact CG2-CZ 3.7Å; I301-F305 PolarHBondContact O-N 3.48Å
302	M	88.4	Confident	88.4	Confident	0 Å²	0	51.8 Å²	51.8	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-65.9	-50	-176.5	-167.4	61.9	68.8	0	0	113.2	A184 M187 I188 A287 S291 Y295 W299 W300 I304 F305 V306	A184-M302 HydrophobicContact CB-SD 4.32Å; M187-M302 HydrophobicContact SD-CE 3.93Å; I188-M302 HydrophobicContact CD1-CE 4.1Å; I188-M302 HydrophobicContact CD1-SD 4.01Å; I188-M302 HydrophobicContact CG1-CE 3.67Å; I188-M302 HydrophobicContact CG1-SD 4.26Å; A287-M302 HydrophobicContact CB-CG 3.96Å; A287-M302 HydrophobicContact CB-SD 4.46Å; A287-M302 WeakPolarHBondContact O-CG 3.46Å; S291-M302 WeakPolarHBondContact OG-CB 3.27Å; Y295-M302 HydrophobicContact CE2-CE 3.8Å; W299-M302 PolarHBondContact O-N 2.92Å; W300-M302 VanDerWaalsContact C-N 3.29Å; W300-M302 PolarHBondContact O-N 3.01Å; M302-I304 PolarHBondContact O-N 2.89Å; M302-F305 PolarHBondContact O-N 3.31Å; M302-F305 VanDerWaalsContact O-N 3.15Å; M302-V306 HydrophobicContact CG-CG2 4.36Å; M302-V306 WeakPolarHBondContact O-CG2 3.35Å; M302-V306 PolarHBondContact O-N 2.91Å; M302-V306 HydrophobicContact SD-CG2 4.31Å
303	P	87.6	Confident	88.2	Confident	5 Å²	5	48.7 Å²	48.7	3%	0.032	24%	0.242	C	C	.	.	H	α-helix	trans	-53.4	-40.7	173.6	-7.8	3	0	0	0	112.9	P136 I288 W299 W300 V306 A307	P136-P303 HydrophobicContact CG-CB 4.1Å; P136-P303 HydrophobicContact CG-CG 4.03Å; I288-P303 HydrophobicContact CD1-CB 3.71Å; I288-P303 HydrophobicContact CD1-CG 3.94Å; I288-P303 HydrophobicContact CG1-CB 4.01Å; I288-P303 HydrophobicContact CG1-CG 3.9Å; I288-P303 HydrophobicContact CG2-CG 4.28Å; W299-P303 HydrophobicContact CE3-CG 4.2Å; W299-P303 HydrophobicContact CZ3-CG 3.96Å; W299-P303 WeakPolarHBondContact O-CD 3.41Å; W300-P303 WeakPolarHBondContact O-CD 3.32Å; P303-V306 PolarHBondContact O-N 3.28Å; P303-A307 WeakPolarHBondContact O-CB 3.46Å; P303-A307 PolarHBondContact O-N 2.98Å
304	I	87.2	Confident	88.2	Confident	81 Å²	81	41.4 Å²	41.4	42%	0.415	21%	0.214	S	C	.	.	H	α-helix	trans	-63.4	-50.1	177.3	-65.7	-179.6	0	0	0	110.6	W300 I301 M302 V306 A307 L308	W300-I304 HydrophobicContact CE3-CD1 3.49Å; W300-I304 VanDerWaalsContact CE3-CD1 3.49Å; W300-I304 HydrophobicContact CZ3-CD1 3.61Å; I301-I304 PolarHBondContact O-N 2.94Å; M302-I304 PolarHBondContact O-N 2.89Å; I304-V306 VanDerWaalsContact C-N 3.31Å; I304-V306 PolarHBondContact O-N 3.42Å; I304-A307 PolarHBondContact O-N 3.27Å; I304-L308 HydrophobicContact CG2-CD1 4.09Å; I304-L308 HydrophobicContact CG2-CG 4.29Å; I304-L308 VanDerWaalsContact O-CG 3.28Å; I304-L308 WeakPolarHBondContact O-CG 3.38Å; I304-L308 PolarHBondContact O-N 3.4Å
305	F	88.7	Confident	88	Confident	53 Å²	53	38.8 Å²	38.8	23%	0.232	20%	0.201	C	C	.	.	H	α-helix	trans	-62.8	-38	-179.7	-73	-5.9	0	0	0	113	A184 M187 I301 M302 L308 S309	A184-F305 HydrophobicContact CB-CB 3.86Å; A184-F305 HydrophobicContact CB-CD2 4.13Å; A184-F305 HydrophobicContact CB-CG 4.48Å; M187-F305 HydrophobicContact CE-CD2 4.39Å; M187-F305 HydrophobicContact CE-CE2 3.83Å; I301-F305 HydrophobicContact CG2-CD1 4.38Å; I301-F305 HydrophobicContact CG2-CD2 3.91Å; I301-F305 HydrophobicContact CG2-CE1 4.1Å; I301-F305 HydrophobicContact CG2-CE2 3.59Å; I301-F305 HydrophobicContact CG2-CG 4.3Å; I301-F305 HydrophobicContact CG2-CZ 3.7Å; I301-F305 PolarHBondContact O-N 3.48Å; M302-F305 PolarHBondContact O-N 3.31Å; M302-F305 VanDerWaalsContact O-N 3.15Å; F305-L308 PolarHBondContact O-N 3.28Å; F305-S309 WeakPolarHBondContact O-CB 3.45Å; F305-S309 PolarHBondContact O-N 3.04Å
306	V	88.9	Confident	87.7	Confident	0 Å²	0	37.2 Å²	37.2	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-69.1	-40.8	175.5	179.4	0	0	0	0	111.4	F46 Y132 A287 M302 P303 I304 L308 S309 T310	F46-V306 HydrophobicContact CB-CG1 3.79Å; F46-V306 HydrophobicContact CD1-CG1 4.09Å; F46-V306 HydrophobicContact CD1-CG2 3.63Å; F46-V306 HydrophobicContact CD2-CB 4.44Å; F46-V306 HydrophobicContact CD2-CG1 3.65Å; F46-V306 HydrophobicContact CD2-CG2 4.23Å; F46-V306 HydrophobicContact CE1-CG2 3.57Å; F46-V306 HydrophobicContact CE2-CG1 4.24Å; F46-V306 HydrophobicContact CE2-CG2 4.18Å; F46-V306 HydrophobicContact CG-CB 4.4Å; F46-V306 HydrophobicContact CG-CG1 3.55Å; F46-V306 HydrophobicContact CG-CG2 3.97Å; F46-V306 HydrophobicContact CZ-CG2 3.86Å; Y132-V306 HydrophobicContact CD1-CB 3.52Å; Y132-V306 HydrophobicContact CD1-CG1 3.33Å; Y132-V306 HydrophobicContact CD1-CG2 4.08Å; Y132-V306 HydrophobicContact CD2-CG1 3.97Å; Y132-V306 HydrophobicContact CE1-CB 3.81Å; Y132-V306 HydrophobicContact CE1-CG1 3.45Å; Y132-V306 VanDerWaalsContact CE1-CG1 3.45Å; Y132-V306 HydrophobicContact CE1-CG2 3.91Å; Y132-V306 HydrophobicContact CE2-CG1 4.06Å; Y132-V306 HydrophobicContact CG-CB 4.14Å; Y132-V306 HydrophobicContact CG-CG1 3.6Å; A287-V306 HydrophobicContact CB-CG2 4.15Å; M302-V306 HydrophobicContact CG-CG2 4.36Å; M302-V306 WeakPolarHBondContact O-CG2 3.35Å; M302-V306 PolarHBondContact O-N 2.91Å; M302-V306 HydrophobicContact SD-CG2 4.31Å; P303-V306 PolarHBondContact O-N 3.28Å; I304-V306 VanDerWaalsContact C-N 3.31Å; I304-V306 PolarHBondContact O-N 3.42Å; V306-L308 VanDerWaalsContact C-N 3.34Å; V306-L308 PolarHBondContact O-N 3Å; V306-S309 WeakPolarHBondContact O-CB 3.41Å; V306-S309 PolarHBondContact O-N 3.47Å; V306-T310 HydrophobicContact CG1-CG2 4.35Å; V306-T310 WeakPolarHBondContact O-CG2 3.32Å; V306-T310 PolarHBondContact O-N 3.02Å; V306-T310 PolarHBondContact O-OG1 2.87Å; V306-T310 VanDerWaalsContact O-OG1 3.05Å
307	A	89.4	Confident	87.5	Confident	4 Å²	4	35.6 Å²	35.6	3%	0.033	18%	0.18	C	C	.	.	H	α-helix	trans	-60.1	-44.6	173.5	0	0	0	0	0	111.2	F129 I133 P303 I304 S309 T310 F311	F129-A307 HydrophobicContact CD2-CB 3.96Å; F129-A307 WeakPolarHBondContact CD2-O 3.39Å; F129-A307 HydrophobicContact CE2-CB 4.11Å; I133-A307 HydrophobicContact CD1-CB 3.91Å; I133-A307 HydrophobicContact CG1-CB 3.48Å; I133-A307 VanDerWaalsContact CG1-CB 3.48Å; P303-A307 WeakPolarHBondContact O-CB 3.46Å; P303-A307 PolarHBondContact O-N 2.98Å; I304-A307 PolarHBondContact O-N 3.27Å; A307-S309 VanDerWaalsContact C-N 3.33Å; A307-S309 PolarHBondContact O-N 3.37Å; A307-T310 WeakPolarHBondContact CA-OG1 3.41Å; A307-T310 PolarHBondContact O-N 2.74Å; A307-T310 PolarHBondContact O-OG1 3.03Å; A307-F311 WeakPolarHBondContact O-CB 3.45Å; A307-F311 PolarHBondContact O-N 3.41Å
308	L	88.3	Confident	87.6	Confident	53 Å²	53	29.5 Å²	29.5	28%	0.277	14%	0.143	S	C	.	.	H	α-helix	trans	-62.2	-40.3	174.8	-66.7	-179.3	0	0	0	111.8	F177 A180 I304 F305 V306 F311 G312	F177-L308 WeakPolarHBondContact CB-O 3.45Å; F177-L308 HydrophobicContact CD1-CB 3.86Å; F177-L308 HydrophobicContact CD1-CD2 3.81Å; F177-L308 HydrophobicContact CD1-CG 4.25Å; F177-L308 HydrophobicContact CE1-CB 4.34Å; F177-L308 HydrophobicContact CE1-CD2 3.37Å; F177-L308 HydrophobicContact CE1-CG 4.27Å; F177-L308 WeakPolarHBondContact CG-O 3.48Å; F177-L308 HydrophobicContact CZ-CD2 4.1Å; A180-L308 HydrophobicContact CB-CB 4.09Å; A180-L308 HydrophobicContact CB-CD1 4.16Å; I304-L308 HydrophobicContact CG2-CD1 4.09Å; I304-L308 HydrophobicContact CG2-CG 4.29Å; I304-L308 VanDerWaalsContact O-CG 3.28Å; I304-L308 WeakPolarHBondContact O-CG 3.38Å; I304-L308 PolarHBondContact O-N 3.4Å; F305-L308 PolarHBondContact O-N 3.28Å; V306-L308 VanDerWaalsContact C-N 3.34Å; V306-L308 PolarHBondContact O-N 3Å; L308-F311 PolarHBondContact O-N 3.49Å; L308-G312 PolarHBondContact O-N 2.99Å
309	S	89.4	Confident	87.3	Confident	1 Å²	1	25.5 Å²	25.5	1%	0.007	12%	0.123	C	C	.	.	H	α-helix	trans	-59.5	-51.2	176	-178.1	0	0	0	0	112.4	G42 K181 F305 V306 A307 F311 G312 G313	G42-S309 PolarHBondContact O-OG 2.86Å; K181-S309 WeakPolarHBondContact CB-OG 3.05Å; F305-S309 WeakPolarHBondContact O-CB 3.45Å; F305-S309 PolarHBondContact O-N 3.04Å; V306-S309 WeakPolarHBondContact O-CB 3.41Å; V306-S309 PolarHBondContact O-N 3.47Å; A307-S309 VanDerWaalsContact C-N 3.33Å; A307-S309 PolarHBondContact O-N 3.37Å; S309-F311 PolarHBondContact O-N 3.11Å; S309-G312 PolarHBondContact O-N 3.05Å; S309-G313 PolarHBondContact O-N 3.27Å
310	T	89.6	Confident	86.9	Confident	0 Å²	0	23.3 Å²	23.3	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-64.2	-40.8	-179.4	51.2	0	0	0	0	111.5	S43 T128 F129 V306 A307 G312 G313 V314	S43-T310 VanDerWaalsContact CB-CG2 3.46Å; T128-T310 HydrophobicContact CG2-CG2 3.54Å; F129-T310 VanDerWaalsContact CA-OG1 3.3Å; F129-T310 WeakPolarHBondContact CA-OG1 3.23Å; F129-T310 VanDerWaalsContact CB-OG1 3.29Å; F129-T310 WeakPolarHBondContact CB-OG1 3.43Å; V306-T310 HydrophobicContact CG1-CG2 4.35Å; V306-T310 WeakPolarHBondContact O-CG2 3.32Å; V306-T310 PolarHBondContact O-N 3.02Å; V306-T310 PolarHBondContact O-OG1 2.87Å; V306-T310 VanDerWaalsContact O-OG1 3.05Å; A307-T310 WeakPolarHBondContact CA-OG1 3.41Å; A307-T310 PolarHBondContact O-N 2.74Å; A307-T310 PolarHBondContact O-OG1 3.03Å; T310-G312 PolarHBondContact O-N 3.29Å; T310-G313 PolarHBondContact O-N 2.92Å; T310-G313 VanDerWaalsContact O-N 3.11Å; T310-V314 WeakPolarHBondContact O-CG2 3.41Å; T310-V314 PolarHBondContact O-N 2.98Å
311	F	88.5	Confident	86.8	Confident	24 Å²	24	16.9 Å²	16.9	11%	0.105	9%	0.094	C	C	.	.	H	α-helix	trans	-62.8	-40.8	175.1	-161.3	-82	0	0	0	111.8	F129 C155 L158 L159 F177 A307 L308 S309 G313 V314 N315	F129-F311 HydrophobicContact CD2-CB 4.1Å; F129-F311 AromaticContact CD2-CD2 3.98Å; F129-F311 HydrophobicContact CD2-CD2 3.98Å; F129-F311 HydrophobicContact CE2-CB 4.28Å; F129-F311 AromaticContact CE2-CD2 3.57Å; F129-F311 HydrophobicContact CE2-CD2 3.57Å; F129-F311 HydrophobicContact CE2-CE2 4.4Å; F129-F311 HydrophobicContact CE2-CG 4.36Å; F129-F311 AromaticContact CZ-CD2 3.88Å; F129-F311 HydrophobicContact CZ-CD2 3.88Å; F129-F311 HydrophobicContact CZ-CE2 4.31Å; C155-F311 HydrophobicContact CB-CE2 4.5Å; C155-F311 WeakPolarHBondContact SG-CD2 3.26Å; L158-F311 HydrophobicContact CD2-CE2 4.33Å; L158-F311 HydrophobicContact CD2-CZ 3.96Å; L158-F311 HydrophobicContact CG-CZ 4.46Å; L159-F311 HydrophobicContact CD1-CD1 3.7Å; L159-F311 HydrophobicContact CD1-CD2 4.09Å; L159-F311 HydrophobicContact CD1-CE1 3.78Å; L159-F311 HydrophobicContact CD1-CE2 4.09Å; L159-F311 HydrophobicContact CD1-CG 3.91Å; L159-F311 HydrophobicContact CD1-CZ 3.95Å; L159-F311 VanDerWaalsContact CD1-O 3.29Å; L159-F311 WeakPolarHBondContact CD1-O 3.39Å; L159-F311 HydrophobicContact CD2-CD1 3.64Å; L159-F311 HydrophobicContact CD2-CE1 3.09Å; L159-F311 HydrophobicContact CD2-CZ 3.62Å; L159-F311 HydrophobicContact CG-CD1 3.95Å; L159-F311 HydrophobicContact CG-CE1 3.48Å; L159-F311 VanDerWaalsContact CG-CE1 3.48Å; L159-F311 HydrophobicContact CG-CE2 4.06Å; L159-F311 HydrophobicContact CG-CG 4.49Å; L159-F311 HydrophobicContact CG-CZ 3.52Å; F177-F311 AromaticContact CD2-CD1 3.96Å; F177-F311 HydrophobicContact CD2-CD1 3.96Å; F177-F311 HydrophobicContact CE2-CB 4.5Å; F177-F311 AromaticContact CE2-CD1 3.25Å; F177-F311 HydrophobicContact CE2-CD1 3.25Å; F177-F311 AromaticContact CE2-CE1 3.73Å; F177-F311 HydrophobicContact CE2-CE1 3.73Å; F177-F311 HydrophobicContact CE2-CG 4.25Å; F177-F311 AromaticContact CZ-CD1 3.91Å; F177-F311 HydrophobicContact CZ-CD1 3.91Å; F177-F311 HydrophobicContact CZ-CE1 4.22Å; A307-F311 WeakPolarHBondContact O-CB 3.45Å; A307-F311 PolarHBondContact O-N 3.41Å; L308-F311 PolarHBondContact O-N 3.49Å; S309-F311 PolarHBondContact O-N 3.11Å; F311-G313 VanDerWaalsContact C-N 3.35Å; F311-V314 PolarHBondContact O-N 2.92Å; F311-N315 PolarHBondContact O-N 2.88Å
312	G	85.8	Confident	86.5	Confident	2 Å²	2	16.1 Å²	16.1	2%	0.021	9%	0.091	C	C	.	.	H	α-helix	trans	-64.9	-33.5	170.8	0	0	0	0	0	113.9	Q174 L308 S309 T310 N315 G316	Q174-G312 PolarHBondContact NE2-O 3.49Å; Q174-G312 PolarHBondContact OE1-O 3.09Å; L308-G312 PolarHBondContact O-N 2.99Å; S309-G312 PolarHBondContact O-N 3.05Å; T310-G312 PolarHBondContact O-N 3.29Å; G312-N315 PolarHBondContact O-N 3.41Å; G312-G316 PolarHBondContact O-N 2.92Å
313	G	86.4	Confident	85.7	Confident	12 Å²	12	21.6 Å²	21.6	12%	0.124	11%	0.112	C	C	.	.	H	α-helix	trans	-64.3	-43.8	174	0	0	0	0	0	112.7	M125 S309 T310 F311 T317	M125-G313 WeakPolarHBondContact CE-O 3.43Å; S309-G313 PolarHBondContact O-N 3.27Å; T310-G313 PolarHBondContact O-N 2.92Å; T310-G313 VanDerWaalsContact O-N 3.11Å; F311-G313 VanDerWaalsContact C-N 3.35Å; G313-T317 WeakPolarHBondContact O-CB 3.4Å; G313-T317 PolarHBondContact O-N 2.84Å; G313-T317 VanDerWaalsContact O-N 3.07Å; G313-T317 PolarHBondContact O-OG1 2.83Å
314	V	90.8	Very high	85.2	Confident	0 Å²	0	22.7 Å²	22.7	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-61.2	-49.4	174.4	175.3	0	0	0	0	110.4	V122 M125 S126 L159 T310 F311 G316 T317 V318	V122-V314 HydrophobicContact CG1-CG1 3.91Å; M125-V314 HydrophobicContact CB-CG2 3.53Å; S126-V314 VanDerWaalsContact OG-CG2 3.23Å; S126-V314 WeakPolarHBondContact OG-CG2 3.36Å; L159-V314 HydrophobicContact CB-CG1 4.26Å; L159-V314 HydrophobicContact CD1-CB 3.5Å; L159-V314 VanDerWaalsContact CD1-CB 3.5Å; L159-V314 HydrophobicContact CD1-CG1 3.38Å; L159-V314 HydrophobicContact CG-CG1 4.47Å; T310-V314 WeakPolarHBondContact O-CG2 3.41Å; T310-V314 PolarHBondContact O-N 2.98Å; F311-V314 PolarHBondContact O-N 2.92Å; V314-G316 PolarHBondContact O-N 2.9Å; V314-T317 PolarHBondContact O-N 3.45Å; V314-V318 HydrophobicContact CG1-CG2 4.37Å; V314-V318 WeakPolarHBondContact O-CG2 3.17Å; V314-V318 PolarHBondContact O-N 3.23Å
315	N	88.4	Confident	84.9	Confident	0 Å²	0	18.9 Å²	18.9	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-58.8	-48.3	-179.2	-173.5	61.7	0	0	0	112.1	L159 N163 S170 Q174 F311 G312 T317 V318 M319	L159-N315 HydrophobicContact CD1-CB 4.3Å; L159-N315 HydrophobicContact CD2-CB 3.74Å; N163-N315 PolarHBondContact ND2-OD1 2.93Å; S170-N315 PolarHBondContact O-ND2 3.24Å; S170-N315 PolarHBondContact OG-ND2 3.31Å; S170-N315 PolarHBondContact OG-OD1 2.93Å; S170-N315 VanDerWaalsContact OG-OD1 3.09Å; Q174-N315 PolarHBondContact OE1-ND2 2.8Å; F311-N315 PolarHBondContact O-N 2.88Å; G312-N315 PolarHBondContact O-N 3.41Å; N315-T317 VanDerWaalsContact C-N 3.28Å; N315-T317 PolarHBondContact O-N 3.2Å; N315-V318 PolarHBondContact O-N 3Å; N315-M319 WeakPolarHBondContact O-CB 3.36Å; N315-M319 PolarHBondContact O-N 3.06Å
316	G	82.6	Confident	84.1	Confident	15 Å²	15	19.5 Å²	19.5	16%	0.155	10%	0.1	C	C	.	.	H	α-helix	trans	-61.5	-35.6	177.6	0	0	0	0	0	113	G312 V314 T320	G312-G316 PolarHBondContact O-N 2.92Å; V314-G316 PolarHBondContact O-N 2.9Å; G316-T320 WeakPolarHBondContact O-CB 3.32Å; G316-T320 WeakPolarHBondContact O-CG2 3.5Å; G316-T320 PolarHBondContact O-N 3.02Å; G316-T320 PolarHBondContact O-OG1 2.86Å
317	T	85.6	Confident	83.2	Confident	12 Å²	12	20.6 Å²	20.6	7%	0.074	11%	0.107	C	C	.	.	H	α-helix	trans	-73.2	-42	178.9	-58.6	0	0	0	0	112	R118 V122 M125 G313 V314 N315 M319 T320 T321	R118-T317 HydrophobicContact CB-CG2 4.32Å; V122-T317 HydrophobicContact CG2-CG2 3.7Å; M125-T317 HydrophobicContact CE-CG2 4.45Å; M125-T317 WeakPolarHBondContact CE-OG1 3.31Å; G313-T317 WeakPolarHBondContact O-CB 3.4Å; G313-T317 PolarHBondContact O-N 2.84Å; G313-T317 VanDerWaalsContact O-N 3.07Å; G313-T317 PolarHBondContact O-OG1 2.83Å; V314-T317 PolarHBondContact O-N 3.45Å; N315-T317 VanDerWaalsContact C-N 3.28Å; N315-T317 PolarHBondContact O-N 3.2Å; T317-M319 VanDerWaalsContact C-N 3.34Å; T317-M319 PolarHBondContact O-N 3.41Å; T317-T320 WeakPolarHBondContact CA-OG1 3.22Å; T317-T320 PolarHBondContact O-N 3.32Å; T317-T320 PolarHBondContact O-OG1 3.49Å; T317-T321 WeakPolarHBondContact O-CB 3.33Å; T317-T321 PolarHBondContact O-N 3.43Å; T317-T321 PolarHBondContact O-OG1 2.98Å
318	V	88	Confident	82.4	Confident	1 Å²	1	20.4 Å²	20.4	1%	0.006	11%	0.106	C	C	.	.	H	α-helix	trans	-61.6	-44.4	174.2	173.9	0	0	0	0	110.5	V122 N163 V314 N315 T321 S322 V352	V122-V318 HydrophobicContact CG2-CG2 4.19Å; N163-V318 HydrophobicContact CB-CG1 3.93Å; V314-V318 HydrophobicContact CG1-CG2 4.37Å; V314-V318 WeakPolarHBondContact O-CG2 3.17Å; V314-V318 PolarHBondContact O-N 3.23Å; N315-V318 PolarHBondContact O-N 3Å; V318-T321 PolarHBondContact O-N 3.01Å; V318-S322 PolarHBondContact O-N 2.8Å; V318-V352 HydrophobicContact CG1-CG1 3.98Å; V318-V352 HydrophobicContact CG1-CG2 4.27Å
319	M	81.5	Confident	81.8	Confident	30 Å²	30	18.5 Å²	18.5	15%	0.148	10%	0.097	C	C	.	.	H	α-helix	trans	-60	-49	178.3	-173.5	180	-177.6	0	0	112	V167 N315 T317 S322	V167-M319 HydrophobicContact CG1-CE 4.14Å; N315-M319 WeakPolarHBondContact O-CB 3.36Å; N315-M319 PolarHBondContact O-N 3.06Å; T317-M319 VanDerWaalsContact C-N 3.34Å; T317-M319 PolarHBondContact O-N 3.41Å; M319-S322 PolarHBondContact O-OG 2.85Å
320	T	79.1	Confident	80.9	Confident	30 Å²	30	24.5 Å²	24.5	18%	0.184	12%	0.124	C	C	.	.	H	α-helix	trans	-70.7	-33.4	-178.7	48.8	0	0	0	0	113.2	R118 G316 T317 S322 R323 M324	R118-T320 PolarHBondContact NH1-OG1 3Å; G316-T320 WeakPolarHBondContact O-CB 3.32Å; G316-T320 WeakPolarHBondContact O-CG2 3.5Å; G316-T320 PolarHBondContact O-N 3.02Å; G316-T320 PolarHBondContact O-OG1 2.86Å; T317-T320 WeakPolarHBondContact CA-OG1 3.22Å; T317-T320 PolarHBondContact O-N 3.32Å; T317-T320 PolarHBondContact O-OG1 3.49Å; T320-S322 VanDerWaalsContact C-N 3.34Å; T320-S322 PolarHBondContact O-N 3.34Å; T320-R323 PolarHBondContact O-N 3.45Å; T320-M324 PolarHBondContact O-N 2.88Å
321	T	83.4	Confident	80.3	Confident	0 Å²	0	26.8 Å²	26.8	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-63.7	-40.1	177.7	-55.7	0	0	0	0	111.6	R118 T317 V318 R323 M324 F325 T355	R118-T321 HydrophobicContact CB-CG2 4.04Å; R118-T321 WeakPolarHBondContact CB-OG1 3.46Å; R118-T321 WeakPolarHBondContact CD-OG1 3.49Å; R118-T321 HydrophobicContact CG-CG2 4.12Å; R118-T321 WeakPolarHBondContact CG-OG1 3.37Å; T317-T321 WeakPolarHBondContact O-CB 3.33Å; T317-T321 PolarHBondContact O-N 3.43Å; T317-T321 PolarHBondContact O-OG1 2.98Å; V318-T321 PolarHBondContact O-N 3.01Å; T321-R323 VanDerWaalsContact C-N 3.27Å; T321-R323 PolarHBondContact O-N 2.86Å; T321-M324 WeakPolarHBondContact O-CB 3.34Å; T321-M324 PolarHBondContact O-N 3.38Å; T321-M324 VanDerWaalsContact O-N 3.11Å; T321-F325 HydrophobicContact CG2-CD2 4.26Å; T321-F325 HydrophobicContact CG2-CE2 3.82Å; T321-F325 WeakPolarHBondContact O-CD2 3.48Å; T321-F325 PolarHBondContact O-N 3.24Å; T321-T355 HydrophobicContact CG2-CG2 4.08Å; T321-T355 WeakPolarHBondContact CG2-OG1 3.43Å
322	S	79.3	Confident	79.8	Confident	15 Å²	15	31 Å²	31	11%	0.105	16%	0.162	C	C	.	.	H	α-helix	trans	-61.3	-33.7	178.5	70.7	0	0	0	0	113.8	V318 M319 T320 F325 F326 P348	V318-S322 PolarHBondContact O-N 2.8Å; M319-S322 PolarHBondContact O-OG 2.85Å; T320-S322 VanDerWaalsContact C-N 3.34Å; T320-S322 PolarHBondContact O-N 3.34Å; S322-F325 PolarHBondContact O-N 2.96Å; S322-F326 PolarHBondContact O-N 2.98Å; S322-P348 VanDerWaalsContact CB-CG 3.46Å
323	R	72.1	Confident	79.6	Confident	116 Å²	116	31.4 Å²	31.4	44%	0.438	16%	0.163	S	C	.	.	H	α-helix	trans	-70.1	-32.7	175.6	-64.8	179.7	-179.3	-178.2	-2	112.6	T320 T321 F326 V327	T320-R323 PolarHBondContact O-N 3.45Å; T321-R323 VanDerWaalsContact C-N 3.27Å; T321-R323 PolarHBondContact O-N 2.86Å; R323-F326 WeakPolarHBondContact O-CB 3.47Å; R323-F326 PolarHBondContact O-N 2.66Å; R323-V327 PolarHBondContact O-N 3.03Å
324	M	76.3	Confident	79.4	Confident	28 Å²	28	31.7 Å²	31.7	14%	0.138	16%	0.162	C	C	.	.	H	α-helix	trans	-65.9	-40	175.9	-81.1	-176.5	166.1	0	0	112.2	E113 T320 T321 F326 V327 A328	E113-M324 HydrophobicContact CG-CE 3.99Å; E113-M324 HydrophobicContact CG-SD 3.54Å; E113-M324 VanDerWaalsContact CG-SD 3.54Å; T320-M324 PolarHBondContact O-N 2.88Å; T321-M324 WeakPolarHBondContact O-CB 3.34Å; T321-M324 PolarHBondContact O-N 3.38Å; T321-M324 VanDerWaalsContact O-N 3.11Å; M324-F326 VanDerWaalsContact C-N 3.3Å; M324-F326 PolarHBondContact O-N 3.2Å; M324-V327 PolarHBondContact O-N 3.28Å; M324-A328 WeakPolarHBondContact O-CB 3.44Å; M324-A328 PolarHBondContact O-N 2.94Å; M324-A328 VanDerWaalsContact O-N 3.07Å
325	F	81.3	Confident	78.8	Confident	1 Å²	1	34.4 Å²	34.4	0%	0.004	18%	0.179	C	C	.	.	H	α-helix	trans	-57.8	-46.7	174.7	-78.9	-68.2	0	0	0	111.1	V114 T321 S322 V327 A328 S329 M334 L338 C339 A351 F354	V114-F325 HydrophobicContact CB-CE1 4.02Å; V114-F325 HydrophobicContact CB-CE2 4.22Å; V114-F325 HydrophobicContact CB-CZ 3.59Å; V114-F325 HydrophobicContact CG1-CE1 4.2Å; V114-F325 HydrophobicContact CG1-CE2 4.34Å; V114-F325 HydrophobicContact CG1-CZ 4Å; V114-F325 HydrophobicContact CG2-CE1 3.92Å; V114-F325 HydrophobicContact CG2-CZ 3.9Å; T321-F325 HydrophobicContact CG2-CD2 4.26Å; T321-F325 HydrophobicContact CG2-CE2 3.82Å; T321-F325 WeakPolarHBondContact O-CD2 3.48Å; T321-F325 PolarHBondContact O-N 3.24Å; S322-F325 PolarHBondContact O-N 2.96Å; F325-V327 PolarHBondContact O-N 2.86Å; F325-A328 WeakPolarHBondContact O-CB 3.4Å; F325-A328 PolarHBondContact O-N 3.21Å; F325-A328 VanDerWaalsContact O-N 3.11Å; F325-S329 PolarHBondContact O-N 3.44Å; F325-M334 HydrophobicContact CD1-CG 4.39Å; F325-M334 HydrophobicContact CD1-SD 4.45Å; F325-M334 HydrophobicContact CE1-CE 4.31Å; F325-M334 HydrophobicContact CE1-SD 4.24Å; F325-L338 HydrophobicContact CD1-CB 4.08Å; F325-L338 HydrophobicContact CD1-CD1 3.85Å; F325-L338 HydrophobicContact CE1-CD1 3.71Å; F325-L338 HydrophobicContact CG-CB 4.44Å; F325-C339 PolarHBondContact O-SG 3.32Å; F325-A351 HydrophobicContact CB-CB 4.12Å; F325-A351 HydrophobicContact CD2-CB 3.66Å; F325-A351 HydrophobicContact CE2-CB 4.42Å; F325-A351 HydrophobicContact CG-CB 4.11Å; F325-F354 HydrophobicContact CE1-CD1 4.29Å; F325-F354 HydrophobicContact CE1-CE1 4.38Å; F325-F354 AromaticContact CE2-CD1 3.99Å; F325-F354 HydrophobicContact CE2-CD1 3.99Å; F325-F354 AromaticContact CZ-CD1 3.4Å; F325-F354 HydrophobicContact CZ-CD1 3.4Å; F325-F354 VanDerWaalsContact CZ-CD1 3.4Å; F325-F354 AromaticContact CZ-CE1 3.65Å; F325-F354 HydrophobicContact CZ-CE1 3.65Å; F325-F354 HydrophobicContact CZ-CG 4.31Å
326	F	71.8	Confident	78.3	Confident	65 Å²	65	40.5 Å²	40.5	29%	0.285	21%	0.206	S	C	.	.	H	α-helix	trans	-50.8	-55.3	178.9	-173.3	-91.6	0	0	0	112.3	S322 R323 M324 A328 S329 S480	S322-F326 PolarHBondContact O-N 2.98Å; R323-F326 WeakPolarHBondContact O-CB 3.47Å; R323-F326 PolarHBondContact O-N 2.66Å; M324-F326 VanDerWaalsContact C-N 3.3Å; M324-F326 PolarHBondContact O-N 3.2Å; F326-A328 VanDerWaalsContact C-N 3.33Å; F326-A328 PolarHBondContact O-N 2.93Å; F326-S329 PolarHBondContact O-N 3.01Å; F326-S329 PolarHBondContact O-OG 3.39Å; F326-S480 WeakPolarHBondContact CE2-OG 3.43Å
327	V	69.9	Low	78.3	Confident	24 Å²	24	40.6 Å²	40.6	15%	0.145	20%	0.203	C	C	.	.	H	α-helix	trans	-60.6	-42	178.8	176.8	0	0	0	0	111.6	S90 R323 M324 F325 S329 Q330	S90-V327 VanDerWaalsContact O-CG1 3.25Å; S90-V327 WeakPolarHBondContact O-CG1 3.39Å; R323-V327 PolarHBondContact O-N 3.03Å; M324-V327 PolarHBondContact O-N 3.28Å; F325-V327 PolarHBondContact O-N 2.86Å; V327-S329 VanDerWaalsContact C-N 3.29Å; V327-S329 PolarHBondContact O-N 3.18Å; V327-Q330 PolarHBondContact O-N 3.21Å
328	A	73.5	Confident	78.1	Confident	0 Å²	0	41.2 Å²	41.2	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-63.6	-31.9	-178.6	0	0	0	0	0	113.8	L110 M324 F325 F326 V331 Q333 M334	L110-A328 HydrophobicContact CD1-CB 3.89Å; L110-A328 HydrophobicContact CD2-CB 3.3Å; L110-A328 HydrophobicContact CG-CB 4.23Å; M324-A328 WeakPolarHBondContact O-CB 3.44Å; M324-A328 PolarHBondContact O-N 2.94Å; M324-A328 VanDerWaalsContact O-N 3.07Å; F325-A328 WeakPolarHBondContact O-CB 3.4Å; F325-A328 PolarHBondContact O-N 3.21Å; F325-A328 VanDerWaalsContact O-N 3.11Å; F326-A328 VanDerWaalsContact C-N 3.33Å; F326-A328 PolarHBondContact O-N 2.93Å; A328-V331 PolarHBondContact O-N 3.5Å; A328-Q333 PolarHBondContact O-N 3.48Å; A328-M334 HydrophobicContact CB-CB 4.11Å; A328-M334 HydrophobicContact CB-CG 3.74Å
329	S	73.6	Confident	77.7	Confident	13 Å²	13	41.3 Å²	41.3	9%	0.091	21%	0.206	C	C	.	.	H	α-helix	trans	-73	-28.7	176.9	68.9	0	0	0	0	114.1	F325 F326 V327 V331 N332 C339	F325-S329 PolarHBondContact O-N 3.44Å; F326-S329 PolarHBondContact O-N 3.01Å; F326-S329 PolarHBondContact O-OG 3.39Å; V327-S329 VanDerWaalsContact C-N 3.29Å; V327-S329 PolarHBondContact O-N 3.18Å; S329-V331 PolarHBondContact O-N 3.39Å; S329-N332 PolarHBondContact O-N 3.02Å; S329-C339 WeakPolarHBondContact CB-SG 3.23Å; S329-C339 WeakPolarHBondContact OG-CB 3.49Å; S329-C339 PolarHBondContact OG-SG 2.97Å
330	Q	72.2	Confident	77.7	Confident	126 Å²	126	40.7 Å²	40.7	59%	0.589	20%	0.202	S	C	*	.	H	α-helix	trans	-62.5	-25.9	177.3	-66	-172.9	-26.3	0	0	111.5	V327	V327-Q330 PolarHBondContact O-N 3.21Å
331	V	76.5	Confident	77.9	Confident	48 Å²	48	40.6 Å²	40.6	29%	0.291	20%	0.201	S	C	.	.	T	Hydrogen-bonded Turn	trans	-97.7	13.7	176.9	-156	0	0	0	0	112.3	Y94 Y98 A328 S329 Q333	Y94-V331 HydrophobicContact CE1-CG2 4.25Å; Y98-V331 HydrophobicContact CE2-CG1 3.79Å; A328-V331 PolarHBondContact O-N 3.5Å; S329-V331 PolarHBondContact O-N 3.39Å; V331-Q333 HydrophobicContact CB-CG 4.44Å; V331-Q333 PolarHBondContact O-N 3.02Å; V331-Q333 VanDerWaalsContact O-N 3.08Å
332	N	77.6	Confident	77.9	Confident	114 Å²	114	42 Å²	42	61%	0.61	21%	0.207	S	C	*	.	T	Hydrogen-bonded Turn	trans	53.4	25.3	-177.8	-63.7	-59.7	0	0	0	114.7	S329	S329-N332 PolarHBondContact O-N 3.02Å
333	Q	82.1	Confident	78	Confident	10 Å²	10	45.9 Å²	45.9	5%	0.047	23%	0.225	C	C	.	.	S	Bend	trans	-91.1	-16.6	178	-69.9	-144.6	-19.3	0	0	113.3	Y94 P103 F107 A328 V331	Y94-Q333 WeakPolarHBondContact OH-CG 3.29Å; Y94-Q333 PolarHBondContact OH-OE1 2.64Å; Y94-Q333 VanDerWaalsContact OH-OE1 3.09Å; P103-Q333 PolarHBondContact O-NE2 3.49Å; F107-Q333 HydrophobicContact CD2-CB 4.26Å; F107-Q333 VanDerWaalsContact CE2-O 3.28Å; F107-Q333 WeakPolarHBondContact CE2-O 3.43Å; A328-Q333 PolarHBondContact O-N 3.48Å; V331-Q333 HydrophobicContact CB-CG 4.44Å; V331-Q333 PolarHBondContact O-N 3.02Å; V331-Q333 VanDerWaalsContact O-N 3.08Å
334	M	81.6	Confident	78.4	Confident	18 Å²	18	46 Å²	46	9%	0.089	24%	0.235	C	C	.	.	S	Bend	trans	-122.4	151.8	174.9	-80.6	-70.6	177.3	0	0	111.3	L110 V114 F325 A328 K336 L338	L110-M334 HydrophobicContact CD2-CE 3.6Å; L110-M334 HydrophobicContact CD2-CG 3.69Å; L110-M334 HydrophobicContact CG-CE 3.9Å; V114-M334 HydrophobicContact CG2-CE 3.71Å; F325-M334 HydrophobicContact CD1-CG 4.39Å; F325-M334 HydrophobicContact CD1-SD 4.45Å; F325-M334 HydrophobicContact CE1-CE 4.31Å; F325-M334 HydrophobicContact CE1-SD 4.24Å; A328-M334 HydrophobicContact CB-CB 4.11Å; A328-M334 HydrophobicContact CB-CG 3.74Å; M334-K336 PolarHBondContact O-N 3.14Å; M334-L338 HydrophobicContact SD-CD1 4.29Å
335	P	79	Confident	78.5	Confident	56 Å²	56	50.9 Å²	50.9	36%	0.364	25%	0.251	S	S	.	.			trans	-51.7	127.6	169.5	-27.7	36.3	0	0	0	111.7	L337 L338 F464	P335-L337 PolarHBondContact O-N 2.94Å; P335-L338 PolarHBondContact O-N 3.44Å; P335-F464 HydrophobicContact CB-CZ 4.11Å
336	K	78.3	Confident	78.6	Confident	129 Å²	129	56.6 Å²	56.6	56%	0.561	28%	0.279	S	S	*	.	G	3₁₀ helix	trans	-52.7	-31.4	178.2	-66.2	-172.5	178	-175	0	112.9	M334 L338 C339 F340	M334-K336 PolarHBondContact O-N 3.14Å; K336-L338 PolarHBondContact O-N 2.84Å; K336-C339 PolarHBondContact O-N 3.42Å; K336-F340 HydrophobicContact CB-CE1 3.86Å; K336-F340 HydrophobicContact CB-CZ 4.04Å; K336-F340 WeakPolarHBondContact O-CD1 3.47Å; K336-F340 WeakPolarHBondContact O-CE1 3.4Å; K336-F340 PolarHBondContact O-N 3.23Å
337	L	81.3	Confident	79.1	Confident	17 Å²	17	53.5 Å²	53.5	9%	0.089	27%	0.266	C	S	.	.	G	3₁₀ helix	trans	-52.3	-39.1	177.2	-179.6	63.5	0	0	0	113.4	P335 C339 F340 S350 F467 T468 V471 L477	P335-L337 PolarHBondContact O-N 2.94Å; L337-C339 PolarHBondContact O-N 3.47Å; L337-C339 VanDerWaalsContact O-N 3.13Å; L337-F340 HydrophobicContact CD1-CD2 3.94Å; L337-F340 HydrophobicContact CD1-CE2 4.23Å; L337-F340 PolarHBondContact O-N 3.36Å; L337-S350 VanDerWaalsContact O-CB 3.31Å; L337-S350 WeakPolarHBondContact O-CB 3.21Å; L337-S350 PolarHBondContact O-OG 3.27Å; L337-F467 HydrophobicContact CD2-CD1 4.29Å; L337-F467 HydrophobicContact CD2-CE1 3.72Å; L337-T468 HydrophobicContact CB-CG2 4.31Å; L337-T468 HydrophobicContact CD1-CG2 4.22Å; L337-V471 HydrophobicContact CD1-CB 3.76Å; L337-V471 HydrophobicContact CD1-CG1 3.66Å; L337-V471 HydrophobicContact CD2-CB 4.12Å; L337-V471 HydrophobicContact CD2-CG1 4.12Å; L337-V471 HydrophobicContact CD2-CG2 4.13Å; L337-V471 HydrophobicContact CG-CG1 4.33Å; L337-L477 HydrophobicContact CD1-CD1 4.39Å
338	L	82.4	Confident	79.9	Confident	24 Å²	24	53.3 Å²	53.3	13%	0.126	27%	0.265	C	S	.	.	G	3₁₀ helix	trans	-70.6	-6.3	-178	-65.8	177.3	0	0	0	113.1	F325 M334 P335 K336 S350 A351 F354	F325-L338 HydrophobicContact CD1-CB 4.08Å; F325-L338 HydrophobicContact CD1-CD1 3.85Å; F325-L338 HydrophobicContact CE1-CD1 3.71Å; F325-L338 HydrophobicContact CG-CB 4.44Å; M334-L338 HydrophobicContact SD-CD1 4.29Å; P335-L338 PolarHBondContact O-N 3.44Å; K336-L338 PolarHBondContact O-N 2.84Å; L338-S350 WeakPolarHBondContact CA-OG 3.43Å; L338-A351 WeakPolarHBondContact O-CB 3.3Å; L338-F354 HydrophobicContact CD2-CB 4Å; L338-F354 HydrophobicContact CD2-CD2 4.5Å; L338-F354 HydrophobicContact CD2-CG 4.36Å
339	C	79.5	Confident	80.6	Confident	4 Å²	4	54.2 Å²	54.2	3%	0.027	27%	0.27	C	S	.	.	G	3₁₀ helix	trans	-117.9	-0.5	-174.4	-58.1	0	0	0	0	112.9	F325 S329 K336 L337	F325-C339 PolarHBondContact O-SG 3.32Å; S329-C339 WeakPolarHBondContact CB-SG 3.23Å; S329-C339 WeakPolarHBondContact OG-CB 3.49Å; S329-C339 PolarHBondContact OG-SG 2.97Å; K336-C339 PolarHBondContact O-N 3.42Å; L337-C339 PolarHBondContact O-N 3.47Å; L337-C339 VanDerWaalsContact O-N 3.13Å
340	F	81.3	Confident	81.4	Confident	16 Å²	16	54.1 Å²	54.1	7%	0.07	27%	0.269	C	S	.	.			trans	-71.2	145.4	175.8	-61.2	-18.5	0	0	0	111.2	K336 L337 T468 Q472 L477 V478 P479	K336-F340 HydrophobicContact CB-CE1 3.86Å; K336-F340 HydrophobicContact CB-CZ 4.04Å; K336-F340 WeakPolarHBondContact O-CD1 3.47Å; K336-F340 WeakPolarHBondContact O-CE1 3.4Å; K336-F340 PolarHBondContact O-N 3.23Å; L337-F340 HydrophobicContact CD1-CD2 3.94Å; L337-F340 HydrophobicContact CD1-CE2 4.23Å; L337-F340 PolarHBondContact O-N 3.36Å; F340-T468 HydrophobicContact CE2-CG2 3.71Å; F340-T468 HydrophobicContact CZ-CG2 4.25Å; F340-Q472 HydrophobicContact CD2-CG 3.52Å; F340-Q472 HydrophobicContact CE2-CG 3.5Å; F340-Q472 VanDerWaalsContact CE2-CG 3.5Å; F340-L477 HydrophobicContact CB-CB 3.65Å; F340-L477 HydrophobicContact CB-CD1 4.33Å; F340-L477 HydrophobicContact CB-CG 4.46Å; F340-L477 HydrophobicContact CD2-CB 4.26Å; F340-L477 HydrophobicContact CG-CB 4.45Å; F340-V478 CarbonylContact C-O 3.48Å; F340-V478 VanDerWaalsContact CA-O 3.28Å; F340-V478 WeakPolarHBondContact CA-O 3.39Å; F340-V478 WeakPolarHBondContact CB-O 3.42Å; F340-P479 HydrophobicContact CD1-CB 4.18Å; F340-P479 HydrophobicContact CD1-CG 4.38Å; F340-P479 HydrophobicContact CE1-CB 3.93Å; F340-P479 HydrophobicContact CE1-CG 3.93Å; F340-P479 HydrophobicContact CZ-CG 4.34Å
341	L	82.7	Confident	82.1	Confident	29 Å²	29	48.1 Å²	48.1	15%	0.152	24%	0.241	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-105.6	145.2	-179.8	-60.1	176.5	0	0	0	109.7	M343 M346 T347 P348 L477 V478	L341-M343 PolarHBondContact O-N 2.66Å; L341-M346 HydrophobicContact CD1-CE 4.11Å; L341-T347 WeakPolarHBondContact CA-O 3.21Å; L341-P348 HydrophobicContact CD2-CB 3.95Å; L341-L477 CarbonylContact O-C 3.53Å; L341-L477 WeakPolarHBondContact O-CA 3.39Å; L341-V478 PolarHBondContact N-O 2.87Å; L341-V478 WeakPolarHBondContact O-CG2 3.46Å; L341-V478 PolarHBondContact O-N 3.11Å
342	H	83.8	Confident	82.8	Confident	28 Å²	28	46 Å²	46	13%	0.13	23%	0.228	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-67	130.6	171.7	-177.3	-74.3	0	0	0	110.7	D344 R345 M346 T347 I349 F475 L477	H342-D344 IonicContact CE1-OD2 3.82Å; H342-D344 PolarHBondContact ND1-N 2.96Å; H342-D344 VanDerWaalsContact ND1-N 3.12Å; H342-D344 PolarHBondContact O-N 2.95Å; H342-R345 HydrophobicContact CB-CB 4.33Å; H342-R345 PolarHBondContact ND1-N 3.13Å; H342-R345 PolarHBondContact O-N 3.06Å; H342-M346 WeakPolarHBondContact O-CA 3.31Å; H342-M346 PolarHBondContact O-N 3.46Å; H342-T347 PolarHBondContact N-O 3.47Å; H342-I349 HydrophobicContact CB-CD1 3.69Å; H342-I349 HydrophobicContact CB-CG1 4.11Å; H342-I349 VanDerWaalsContact CD2-CD1 3.45Å; H342-I349 WeakPolarHBondContact CD2-CD1 3.34Å; H342-F475 PolarHBondContact CD2-O 3.4Å; H342-L477 HydrophobicContact CB-CD2 4.3Å
343	M	81.2	Confident	83.6	Confident	97 Å²	97	43 Å²	43	48%	0.478	21%	0.214	S	C	.	.	T	Hydrogen-bonded Turn	trans	-51.6	-50.8	-174.1	-77.6	-172.9	-79.1	0	0	113.9	L341 K476 V478	L341-M343 PolarHBondContact O-N 2.66Å; M343-K476 HydrophobicContact CE-CB 3.62Å; M343-K476 HydrophobicContact CE-CG 4.16Å; M343-K476 WeakPolarHBondContact CG-O 3.32Å; M343-K476 PolarHBondContact N-O 3.18Å; M343-V478 HydrophobicContact CG-CB 4.22Å; M343-V478 HydrophobicContact CG-CG1 3.42Å; M343-V478 VanDerWaalsContact CG-CG1 3.42Å; M343-V478 HydrophobicContact CG-CG2 3.8Å; M343-V478 HydrophobicContact SD-CG1 3.73Å
344	D	81.2	Confident	84.1	Confident	120 Å²	120	45.4 Å²	45.4	64%	0.642	22%	0.224	S	C	*	.	T	Hydrogen-bonded Turn	trans	-85.7	-21.8	-173	-50.8	-39.1	0	0	0	114	H342	H342-D344 IonicContact CE1-OD2 3.82Å; H342-D344 PolarHBondContact ND1-N 2.96Å; H342-D344 VanDerWaalsContact ND1-N 3.12Å; H342-D344 PolarHBondContact O-N 2.95Å
345	R	78.6	Confident	84.6	Confident	129 Å²	129	44.6 Å²	44.6	49%	0.487	22%	0.22	S	C	.	.	T	Hydrogen-bonded Turn	trans	-112	-16.8	-167.6	-62.1	-62.3	-170.2	-172.8	0.6	112.7	F165 H342 T347	F165-R345 WeakPolarHBondContact O-CD 3.32Å; H342-R345 HydrophobicContact CB-CB 4.33Å; H342-R345 PolarHBondContact ND1-N 3.13Å; H342-R345 PolarHBondContact O-N 3.06Å; R345-T347 HydrophobicContact CB-CG2 4.12Å; R345-T347 PolarHBondContact O-N 3.17Å
346	M	81.7	Confident	85.4	Confident	121 Å²	121	42.6 Å²	42.6	60%	0.596	21%	0.208	S	C	*	.			trans	53.8	33.4	-174.6	-58.5	-64.3	-74.8	0	0	112.6	L341 H342	L341-M346 HydrophobicContact CD1-CE 4.11Å; H342-M346 WeakPolarHBondContact O-CA 3.31Å; H342-M346 PolarHBondContact O-N 3.46Å
347	T	83.2	Confident	86.2	Confident	0 Å²	0	41.2 Å²	41.2	0%	0	21%	0.205	C	C	.	.			trans	-104.3	141.4	-179.4	48.7	0	0	0	0	111.6	A164 V167 L341 H342 R345 I349	A164-T347 VanDerWaalsContact O-CB 3.25Å; A164-T347 WeakPolarHBondContact O-CB 3.5Å; A164-T347 PolarHBondContact O-OG1 2.88Å; V167-T347 HydrophobicContact CG2-CG2 3.72Å; L341-T347 WeakPolarHBondContact CA-O 3.21Å; H342-T347 PolarHBondContact N-O 3.47Å; R345-T347 HydrophobicContact CB-CG2 4.12Å; R345-T347 PolarHBondContact O-N 3.17Å; T347-I349 VanDerWaalsContact C-N 3.31Å; T347-I349 PolarHBondContact O-N 2.61Å
348	P	86.5	Confident	86.8	Confident	20 Å²	20	41.5 Å²	41.5	13%	0.13	21%	0.208	C	C	.	.			trans	-83.5	67.9	-179.8	34	-36	0	0	0	111.8	S322 L341 S350 A351 V352	S322-P348 VanDerWaalsContact CB-CG 3.46Å; L341-P348 HydrophobicContact CD2-CB 3.95Å; P348-S350 VanDerWaalsContact C-N 3.31Å; P348-S350 PolarHBondContact O-N 2.95Å; P348-A351 HydrophobicContact CB-CB 4.32Å; P348-A351 PolarHBondContact O-N 2.9Å; P348-V352 WeakPolarHBondContact O-CG2 3.36Å; P348-V352 PolarHBondContact O-N 3.4Å; P348-V352 VanDerWaalsContact O-N 3.16Å
349	I	89	Confident	87.4	Confident	20 Å²	20	40.3 Å²	40.3	10%	0.103	20%	0.202	C	C	.	.	H	α-helix	trans	-56.8	-42.5	-172.6	-60.6	-177.1	0	0	0	112.1	A164 H342 T347 A351 V352 V353 F475 L477	A164-I349 HydrophobicContact CB-CG1 4.13Å; A164-I349 HydrophobicContact CB-CG2 4.39Å; H342-I349 HydrophobicContact CB-CD1 3.69Å; H342-I349 HydrophobicContact CB-CG1 4.11Å; H342-I349 VanDerWaalsContact CD2-CD1 3.45Å; H342-I349 WeakPolarHBondContact CD2-CD1 3.34Å; T347-I349 VanDerWaalsContact C-N 3.31Å; T347-I349 PolarHBondContact O-N 2.61Å; I349-A351 PolarHBondContact O-N 3.27Å; I349-V352 PolarHBondContact O-N 3.11Å; I349-V353 HydrophobicContact CG2-CG2 4.05Å; I349-V353 WeakPolarHBondContact O-CB 3.18Å; I349-V353 VanDerWaalsContact O-CG2 3.28Å; I349-V353 WeakPolarHBondContact O-CG2 3.21Å; I349-V353 PolarHBondContact O-N 3.4Å; I349-F475 HydrophobicContact CG2-CD1 4.1Å; I349-F475 HydrophobicContact CG2-CE1 4.45Å; I349-F475 HydrophobicContact CG2-CG 4.3Å; I349-L477 HydrophobicContact CB-CD2 4.22Å
350	S	88.9	Confident	88.2	Confident	10 Å²	10	42.1 Å²	42.1	7%	0.07	21%	0.211	C	C	.	.	H	α-helix	trans	-63.8	-42.2	-177.3	52.3	0	0	0	0	113	L337 L338 P348 V353 F354	L337-S350 VanDerWaalsContact O-CB 3.31Å; L337-S350 WeakPolarHBondContact O-CB 3.21Å; L337-S350 PolarHBondContact O-OG 3.27Å; L338-S350 WeakPolarHBondContact CA-OG 3.43Å; P348-S350 VanDerWaalsContact C-N 3.31Å; P348-S350 PolarHBondContact O-N 2.95Å; S350-V353 PolarHBondContact O-N 2.75Å; S350-F354 PolarHBondContact O-N 2.82Å
351	A	88.6	Confident	88.8	Confident	0 Å²	0	44.9 Å²	44.9	0%	0	23%	0.231	C	C	.	.	H	α-helix	trans	-63.7	-41.4	174.3	0	0	0	0	0	112.3	F325 L338 P348 I349 F354 T355	F325-A351 HydrophobicContact CB-CB 4.12Å; F325-A351 HydrophobicContact CD2-CB 3.66Å; F325-A351 HydrophobicContact CE2-CB 4.42Å; F325-A351 HydrophobicContact CG-CB 4.11Å; L338-A351 WeakPolarHBondContact O-CB 3.3Å; P348-A351 HydrophobicContact CB-CB 4.32Å; P348-A351 PolarHBondContact O-N 2.9Å; I349-A351 PolarHBondContact O-N 3.27Å; A351-F354 PolarHBondContact O-N 3Å; A351-T355 PolarHBondContact O-N 2.94Å; A351-T355 PolarHBondContact O-OG1 3.03Å
352	V	91.1	Very high	89.3	Confident	3 Å²	3	44.4 Å²	44.4	2%	0.018	23%	0.227	C	C	.	.	H	α-helix	trans	-66.1	-43.8	179.1	174.2	0	0	0	0	110.6	S160 N163 A164 V318 P348 I349 F354 T355 C356	S160-V352 WeakPolarHBondContact O-CG1 3.48Å; N163-V352 HydrophobicContact CB-CG1 4.26Å; N163-V352 HydrophobicContact CB-CG2 4.23Å; A164-V352 HydrophobicContact CB-CG1 4.35Å; V318-V352 HydrophobicContact CG1-CG1 3.98Å; V318-V352 HydrophobicContact CG1-CG2 4.27Å; P348-V352 WeakPolarHBondContact O-CG2 3.36Å; P348-V352 PolarHBondContact O-N 3.4Å; P348-V352 VanDerWaalsContact O-N 3.16Å; I349-V352 PolarHBondContact O-N 3.11Å; V352-F354 PolarHBondContact O-N 3.39Å; V352-T355 PolarHBondContact O-N 2.79Å; V352-C356 VanDerWaalsContact O-CB 3.28Å; V352-C356 WeakPolarHBondContact O-CB 3.23Å; V352-C356 PolarHBondContact O-N 3Å
353	V	92.8	Very high	89.7	Confident	52 Å²	52	43.2 Å²	43.2	32%	0.315	22%	0.222	S	C	.	.	H	α-helix	trans	-61.7	-44	175.8	169.9	0	0	0	0	111.1	I349 S350 T355 C356 I357	I349-V353 HydrophobicContact CG2-CG2 4.05Å; I349-V353 WeakPolarHBondContact O-CB 3.18Å; I349-V353 VanDerWaalsContact O-CG2 3.28Å; I349-V353 WeakPolarHBondContact O-CG2 3.21Å; I349-V353 PolarHBondContact O-N 3.4Å; S350-V353 PolarHBondContact O-N 2.75Å; V353-T355 PolarHBondContact O-N 3.45Å; V353-C356 WeakPolarHBondContact O-CB 3.22Å; V353-C356 PolarHBondContact O-N 2.99Å; V353-I357 HydrophobicContact CG1-CD1 3.71Å; V353-I357 HydrophobicContact CG1-CG1 4.39Å; V353-I357 VanDerWaalsContact O-CG1 3.31Å; V353-I357 WeakPolarHBondContact O-CG1 3.35Å; V353-I357 PolarHBondContact O-N 3.31Å
354	F	92.7	Very high	90.1	Very high	61 Å²	61	45.7 Å²	45.7	27%	0.268	23%	0.23	S	C	.	.	H	α-helix	trans	-57.8	-51.2	175.5	179.3	-91.7	0	0	0	111.2	V115 F325 L338 S350 A351 V352 C356 I357 T358	V115-F354 HydrophobicContact CG2-CZ 4.34Å; F325-F354 HydrophobicContact CE1-CD1 4.29Å; F325-F354 HydrophobicContact CE1-CE1 4.38Å; F325-F354 AromaticContact CE2-CD1 3.99Å; F325-F354 HydrophobicContact CE2-CD1 3.99Å; F325-F354 AromaticContact CZ-CD1 3.4Å; F325-F354 HydrophobicContact CZ-CD1 3.4Å; F325-F354 VanDerWaalsContact CZ-CD1 3.4Å; F325-F354 AromaticContact CZ-CE1 3.65Å; F325-F354 HydrophobicContact CZ-CE1 3.65Å; F325-F354 HydrophobicContact CZ-CG 4.31Å; L338-F354 HydrophobicContact CD2-CB 4Å; L338-F354 HydrophobicContact CD2-CD2 4.5Å; L338-F354 HydrophobicContact CD2-CG 4.36Å; S350-F354 PolarHBondContact O-N 2.82Å; A351-F354 PolarHBondContact O-N 3Å; V352-F354 PolarHBondContact O-N 3.39Å; F354-C356 VanDerWaalsContact C-N 3.31Å; F354-C356 PolarHBondContact O-N 3.48Å; F354-I357 PolarHBondContact O-N 3.49Å; F354-T358 HydrophobicContact CD1-CG2 4.24Å; F354-T358 HydrophobicContact CE1-CG2 3.79Å; F354-T358 HydrophobicContact CE2-CG2 4.14Å; F354-T358 HydrophobicContact CZ-CG2 3.74Å; F354-T358 PolarHBondContact O-N 3.05Å; F354-T358 PolarHBondContact O-OG1 3.35Å
355	T	92.9	Very high	90.1	Very high	0 Å²	0	43.3 Å²	43.3	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-60	-42.5	179.7	-51.7	0	0	0	0	111.2	T321 A351 V352 V353 T358 S359	T321-T355 HydrophobicContact CG2-CG2 4.08Å; T321-T355 WeakPolarHBondContact CG2-OG1 3.43Å; A351-T355 PolarHBondContact O-N 2.94Å; A351-T355 PolarHBondContact O-OG1 3.03Å; V352-T355 PolarHBondContact O-N 2.79Å; V353-T355 PolarHBondContact O-N 3.45Å; T355-T358 WeakPolarHBondContact CA-OG1 3.38Å; T355-T358 PolarHBondContact O-OG1 3.44Å; T355-S359 VanDerWaalsContact O-CB 3.26Å; T355-S359 WeakPolarHBondContact O-CB 3.42Å; T355-S359 PolarHBondContact O-N 3.12Å; T355-S359 PolarHBondContact O-OG 3.34Å
356	C	95.2	Very high	89.9	Confident	15 Å²	15	39 Å²	39	10%	0.101	22%	0.215	C	C	.	.	H	α-helix	trans	-58.8	-53.2	176.8	-178.3	0	0	0	0	111.4	I156 S160 V352 V353 F354 T358 S359 I360	I156-C356 HydrophobicContact CG2-CB 4.45Å; S160-C356 WeakPolarHBondContact OG-CB 3.49Å; V352-C356 VanDerWaalsContact O-CB 3.28Å; V352-C356 WeakPolarHBondContact O-CB 3.23Å; V352-C356 PolarHBondContact O-N 3Å; V353-C356 WeakPolarHBondContact O-CB 3.22Å; V353-C356 PolarHBondContact O-N 2.99Å; F354-C356 VanDerWaalsContact C-N 3.31Å; F354-C356 PolarHBondContact O-N 3.48Å; C356-T358 PolarHBondContact O-N 3.25Å; C356-S359 PolarHBondContact O-N 3.17Å; C356-I360 WeakPolarHBondContact O-CG1 3.47Å; C356-I360 PolarHBondContact O-N 3.36Å
357	I	95.7	Very high	90	Very high	99 Å²	99	36.6 Å²	36.6	51%	0.508	21%	0.205	S	C	.	.	H	α-helix	trans	-60.1	-49.8	-179.3	-67.9	167.9	0	0	0	110.4	V353 F354 S359 I360 C361	V353-I357 HydrophobicContact CG1-CD1 3.71Å; V353-I357 HydrophobicContact CG1-CG1 4.39Å; V353-I357 VanDerWaalsContact O-CG1 3.31Å; V353-I357 WeakPolarHBondContact O-CG1 3.35Å; V353-I357 PolarHBondContact O-N 3.31Å; F354-I357 PolarHBondContact O-N 3.49Å; I357-S359 VanDerWaalsContact C-N 3.27Å; I357-S359 PolarHBondContact O-N 3.45Å; I357-I360 PolarHBondContact O-N 3Å; I357-C361 PolarHBondContact O-N 3.31Å; I357-C361 PolarHBondContact O-SG 2.93Å; I357-C361 VanDerWaalsContact O-SG 3.33Å
358	T	94.1	Very high	90	Very high	23 Å²	23	37 Å²	37	14%	0.141	21%	0.207	C	C	.	.	H	α-helix	trans	-62	-37.6	179.5	51.3	0	0	0	0	111.7	P119 F354 T355 C356 C361 Y362	P119-T358 VanDerWaalsContact CG-OG1 3.25Å; P119-T358 WeakPolarHBondContact CG-OG1 3.32Å; F354-T358 HydrophobicContact CD1-CG2 4.24Å; F354-T358 HydrophobicContact CE1-CG2 3.79Å; F354-T358 HydrophobicContact CE2-CG2 4.14Å; F354-T358 HydrophobicContact CZ-CG2 3.74Å; F354-T358 PolarHBondContact O-N 3.05Å; F354-T358 PolarHBondContact O-OG1 3.35Å; T355-T358 WeakPolarHBondContact CA-OG1 3.38Å; T355-T358 PolarHBondContact O-OG1 3.44Å; C356-T358 PolarHBondContact O-N 3.25Å; T358-C361 WeakPolarHBondContact O-CB 3.47Å; T358-C361 PolarHBondContact O-N 3.05Å; T358-Y362 VanDerWaalsContact O-CD2 3.25Å; T358-Y362 WeakPolarHBondContact O-CD2 3.47Å; T358-Y362 PolarHBondContact O-N 3.48Å
359	S	95.4	Very high	90	Very high	0 Å²	0	38.2 Å²	38.2	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-69.7	-38.1	179.4	-53.5	0	0	0	0	111.7	P119 V122 T355 C356 I357 C361 Y362 L363	P119-S359 WeakPolarHBondContact CA-OG 3.16Å; V122-S359 WeakPolarHBondContact CB-OG 3.42Å; V122-S359 WeakPolarHBondContact CG1-OG 3.43Å; T355-S359 VanDerWaalsContact O-CB 3.26Å; T355-S359 WeakPolarHBondContact O-CB 3.42Å; T355-S359 PolarHBondContact O-N 3.12Å; T355-S359 PolarHBondContact O-OG 3.34Å; C356-S359 PolarHBondContact O-N 3.17Å; I357-S359 VanDerWaalsContact C-N 3.27Å; I357-S359 PolarHBondContact O-N 3.45Å; S359-C361 VanDerWaalsContact C-N 3.31Å; S359-C361 PolarHBondContact O-N 2.83Å; S359-Y362 PolarHBondContact O-N 3.19Å; S359-L363 PolarHBondContact O-N 3.26Å
360	I	95.8	Very high	89.9	Confident	42 Å²	42	39.1 Å²	39.1	22%	0.215	22%	0.218	C	C	.	.	H	α-helix	trans	-62.5	-39.3	172.8	-69.4	168	0	0	0	110.5	I156 I157 C356 I357 Y362 L363 F364	I156-I360 HydrophobicContact CG2-CG1 4.33Å; I157-I360 HydrophobicContact CD1-CD1 4.16Å; I157-I360 HydrophobicContact CG1-CD1 3.88Å; C356-I360 WeakPolarHBondContact O-CG1 3.47Å; C356-I360 PolarHBondContact O-N 3.36Å; I357-I360 PolarHBondContact O-N 3Å; I360-Y362 VanDerWaalsContact C-N 3.28Å; I360-Y362 PolarHBondContact O-N 2.95Å; I360-L363 WeakPolarHBondContact O-CB 3.42Å; I360-L363 PolarHBondContact O-N 3.37Å; I360-L363 VanDerWaalsContact O-N 3.07Å; I360-F364 HydrophobicContact CG2-CE2 4.03Å; I360-F364 VanDerWaalsContact O-CD2 3.25Å; I360-F364 WeakPolarHBondContact O-CD2 3.3Å; I360-F364 WeakPolarHBondContact O-CE2 3.3Å
361	C	94.4	Very high	89.8	Confident	73 Å²	73	38.8 Å²	38.8	49%	0.493	22%	0.215	S	C	.	.	H	α-helix	trans	-58.2	-41.2	173.9	-66.4	0	0	0	0	112	I357 T358 S359 L363 F364	I357-C361 PolarHBondContact O-N 3.31Å; I357-C361 PolarHBondContact O-SG 2.93Å; I357-C361 VanDerWaalsContact O-SG 3.33Å; T358-C361 WeakPolarHBondContact O-CB 3.47Å; T358-C361 PolarHBondContact O-N 3.05Å; S359-C361 VanDerWaalsContact C-N 3.31Å; S359-C361 PolarHBondContact O-N 2.83Å; C361-L363 VanDerWaalsContact C-N 3.26Å; C361-L363 PolarHBondContact O-N 3.48Å; C361-F364 PolarHBondContact O-N 2.95Å; C361-F364 VanDerWaalsContact O-N 3.14Å
362	Y	92.5	Very high	89.9	Confident	19 Å²	19	38.8 Å²	38.8	8%	0.075	22%	0.215	C	C	.	.	H	α-helix	trans	-68	-20.2	176.3	-81.4	-76.4	0	0	0	114.1	V115 V116 P119 A120 T358 S359 I360 F364 V365 L371 Y374	V115-Y362 VanDerWaalsContact O-CE2 3.23Å; V115-Y362 WeakPolarHBondContact O-CE2 3.4Å; V115-Y362 PolarHBondContact O-OH 2.94Å; V115-Y362 VanDerWaalsContact O-OH 3.08Å; V116-Y362 WeakPolarHBondContact CA-OH 3.37Å; P119-Y362 HydrophobicContact CB-CD2 3.67Å; P119-Y362 HydrophobicContact CB-CE2 3.83Å; A120-Y362 HydrophobicContact CB-CD1 4.18Å; A120-Y362 HydrophobicContact CB-CE1 4.25Å; A120-Y362 HydrophobicContact CB-CG 4.33Å; T358-Y362 VanDerWaalsContact O-CD2 3.25Å; T358-Y362 WeakPolarHBondContact O-CD2 3.47Å; T358-Y362 PolarHBondContact O-N 3.48Å; S359-Y362 PolarHBondContact O-N 3.19Å; I360-Y362 VanDerWaalsContact C-N 3.28Å; I360-Y362 PolarHBondContact O-N 2.95Å; Y362-F364 PolarHBondContact O-N 3.49Å; Y362-V365 HydrophobicContact CD1-CB 4.22Å; Y362-V365 HydrophobicContact CD1-CG1 4.48Å; Y362-V365 HydrophobicContact CD1-CG2 4.18Å; Y362-V365 WeakPolarHBondContact O-CB 3.11Å; Y362-V365 PolarHBondContact O-N 3.42Å; Y362-L371 HydrophobicContact CD1-CD2 3.67Å; Y362-L371 HydrophobicContact CE1-CD2 4.5Å; Y362-L371 HydrophobicContact CG-CD2 4.38Å; Y362-Y374 HydrophobicContact CE1-CD1 4.47Å; Y362-Y374 AromaticContact CE1-CE1 3.61Å; Y362-Y374 HydrophobicContact CE1-CE1 3.61Å; Y362-Y374 PolarHBondContact OH-OH 2.77Å
363	L	93.1	Very high	89.7	Confident	4 Å²	4	39.4 Å²	39.4	2%	0.021	22%	0.219	C	C	.	.	T	Hydrogen-bonded Turn	trans	-65.7	-17.4	171.8	-64.8	179.9	0	0	0	113.1	A123 M127 R149 A152 A153 I156 S359 I360 C361	A123-L363 HydrophobicContact CB-CD2 3.92Å; A123-L363 HydrophobicContact CB-CG 4.46Å; M127-L363 HydrophobicContact CG-CD2 3.6Å; M127-L363 HydrophobicContact SD-CD2 4.24Å; R149-L363 WeakPolarHBondContact CD-O 3.28Å; R149-L363 PolarHBondContact NE-O 3.48Å; A152-L363 HydrophobicContact CB-CD1 4.12Å; A152-L363 HydrophobicContact CB-CD2 3.84Å; A153-L363 HydrophobicContact CB-CD1 3.72Å; I156-L363 HydrophobicContact CD1-CD1 3.78Å; I156-L363 HydrophobicContact CD1-CD2 4.24Å; I156-L363 HydrophobicContact CD1-CG 4.05Å; S359-L363 PolarHBondContact O-N 3.26Å; I360-L363 WeakPolarHBondContact O-CB 3.42Å; I360-L363 PolarHBondContact O-N 3.37Å; I360-L363 VanDerWaalsContact O-N 3.07Å; C361-L363 VanDerWaalsContact C-N 3.26Å; C361-L363 PolarHBondContact O-N 3.48Å
364	F	89.7	Confident	89.5	Confident	148 Å²	148	37.5 Å²	37.5	65%	0.649	21%	0.206	S	C	*	.	T	Hydrogen-bonded Turn	trans	-90.2	-8.4	173.3	-59.2	-78.2	0	0	0	112.7	I360 C361 Y362 G366	I360-F364 HydrophobicContact CG2-CE2 4.03Å; I360-F364 VanDerWaalsContact O-CD2 3.25Å; I360-F364 WeakPolarHBondContact O-CD2 3.3Å; I360-F364 WeakPolarHBondContact O-CE2 3.3Å; C361-F364 PolarHBondContact O-N 2.95Å; C361-F364 VanDerWaalsContact O-N 3.14Å; Y362-F364 PolarHBondContact O-N 3.49Å; F364-G366 PolarHBondContact O-N 3.41Å
365	V	80.3	Confident	89.4	Confident	70 Å²	70	34.7 Å²	34.7	42%	0.424	19%	0.194	S	C	.	.	S	Bend	trans	-95.5	95.5	-173.3	-179.1	0	0	0	0	109.4	Y362 L371	Y362-V365 HydrophobicContact CD1-CB 4.22Å; Y362-V365 HydrophobicContact CD1-CG1 4.48Å; Y362-V365 HydrophobicContact CD1-CG2 4.18Å; Y362-V365 WeakPolarHBondContact O-CB 3.11Å; Y362-V365 PolarHBondContact O-N 3.42Å; V365-L371 HydrophobicContact CB-CD2 4.49Å; V365-L371 HydrophobicContact CG1-CD2 4.47Å; V365-L371 WeakPolarHBondContact O-CD1 3.36Å; V365-L371 VanDerWaalsContact O-CG 3.3Å; V365-L371 WeakPolarHBondContact O-CG 3.11Å
366	G	74.4	Confident	89.3	Confident	38 Å²	38	34.8 Å²	34.8	39%	0.392	20%	0.195	S	C	.	.	S	Bend	trans	61	-166.5	168	0	0	0	0	0	115.6	F364	F364-G366 PolarHBondContact O-N 3.41Å
367	D	83.2	Confident	89.1	Confident	72 Å²	72	34.2 Å²	34.2	39%	0.385	19%	0.19	S	C	.	.			trans	-88.2	170.2	174.3	75.6	-64	0	0	0	111.6	Y369 S370 L371	D367-Y369 VanDerWaalsContact C-N 3.31Å; D367-Y369 PolarHBondContact O-N 2.93Å; D367-Y369 WeakPolarHBondContact OD2-CB 3.42Å; D367-Y369 PolarHBondContact OD2-N 3.48Å; D367-S370 PolarHBondContact O-N 3.41Å; D367-S370 WeakPolarHBondContact OD1-CB 3.5Å; D367-S370 PolarHBondContact OD1-N 3.26Å; D367-S370 PolarHBondContact OD1-OG 3.33Å; D367-S370 PolarHBondContact OD2-N 3.04Å; D367-L371 PolarHBondContact O-N 3.35Å; D367-L371 VanDerWaalsContact O-N 3.12Å
368	I	84.8	Confident	88.9	Confident	8 Å²	8	29.6 Å²	29.6	4%	0.041	17%	0.167	C	C	.	.	H	α-helix	trans	-58.7	-40.6	-176.5	-63	177.9	0	0	0	112	V47 I124 M127 K131 L371 I372	V47-I368 HydrophobicContact CG1-CG2 4.01Å; I124-I368 HydrophobicContact CG2-CG2 4Å; M127-I368 HydrophobicContact CB-CD1 3.74Å; M127-I368 HydrophobicContact CB-CG1 3.9Å; M127-I368 HydrophobicContact CE-CG1 3.72Å; M127-I368 HydrophobicContact SD-CG1 3.99Å; K131-I368 HydrophobicContact CD-CD1 3.75Å; I368-L371 WeakPolarHBondContact O-CB 3.26Å; I368-L371 PolarHBondContact O-N 3.32Å; I368-I372 HydrophobicContact CG2-CD1 3.82Å; I368-I372 HydrophobicContact CG2-CG1 4.45Å; I368-I372 VanDerWaalsContact O-CG1 3.27Å; I368-I372 WeakPolarHBondContact O-CG1 3.41Å; I368-I372 PolarHBondContact O-N 3.15Å
369	Y	86.3	Confident	88.8	Confident	46 Å²	46	29 Å²	29	18%	0.18	16%	0.163	C	C	.	.	H	α-helix	trans	-76.3	-38.6	-174.2	-65.8	-69.2	0	0	0	111.7	V47 T50 D367 L371 I372 T373	V47-Y369 HydrophobicContact CG1-CE1 3.91Å; V47-Y369 PolarHBondContact O-OH 2.9Å; T50-Y369 WeakPolarHBondContact CB-OH 3.38Å; D367-Y369 VanDerWaalsContact C-N 3.31Å; D367-Y369 PolarHBondContact O-N 2.93Å; D367-Y369 WeakPolarHBondContact OD2-CB 3.42Å; D367-Y369 PolarHBondContact OD2-N 3.48Å; Y369-L371 VanDerWaalsContact C-N 3.3Å; Y369-L371 PolarHBondContact O-N 2.96Å; Y369-I372 HydrophobicContact CD1-CD1 4.25Å; Y369-I372 WeakPolarHBondContact O-CB 3.29Å; Y369-I372 PolarHBondContact O-N 3.29Å; Y369-I372 VanDerWaalsContact O-N 3.12Å; Y369-T373 PolarHBondContact O-N 3.04Å; Y369-T373 PolarHBondContact O-OG1 3.08Å
370	S	85.9	Confident	88.6	Confident	39 Å²	39	29.1 Å²	29.1	27%	0.273	16%	0.163	S	C	.	.	H	α-helix	trans	-59.7	-42	171.2	-61.3	0	0	0	0	111.9	D367 I372 T373 Y374	D367-S370 PolarHBondContact O-N 3.41Å; D367-S370 WeakPolarHBondContact OD1-CB 3.5Å; D367-S370 PolarHBondContact OD1-N 3.26Å; D367-S370 PolarHBondContact OD1-OG 3.33Å; D367-S370 PolarHBondContact OD2-N 3.04Å; S370-I372 VanDerWaalsContact C-N 3.34Å; S370-I372 PolarHBondContact O-N 3.35Å; S370-T373 PolarHBondContact O-N 3.46Å; S370-Y374 WeakPolarHBondContact O-CB 3.45Å; S370-Y374 PolarHBondContact O-N 3.2Å
371	L	87.6	Confident	88.5	Confident	3 Å²	3	29.7 Å²	29.7	2%	0.016	17%	0.166	C	C	.	.	H	α-helix	trans	-60.5	-41.5	173.4	-88.8	156.3	0	0	0	112.2	A120 I124 M127 Y362 V365 D367 I368 Y369 L375	A120-L371 HydrophobicContact CB-CD2 4.26Å; I124-L371 HydrophobicContact CD1-CB 4.02Å; I124-L371 HydrophobicContact CG1-CB 3.8Å; M127-L371 HydrophobicContact CE-CD1 3.27Å; Y362-L371 HydrophobicContact CD1-CD2 3.67Å; Y362-L371 HydrophobicContact CE1-CD2 4.5Å; Y362-L371 HydrophobicContact CG-CD2 4.38Å; V365-L371 HydrophobicContact CB-CD2 4.49Å; V365-L371 HydrophobicContact CG1-CD2 4.47Å; V365-L371 WeakPolarHBondContact O-CD1 3.36Å; V365-L371 VanDerWaalsContact O-CG 3.3Å; V365-L371 WeakPolarHBondContact O-CG 3.11Å; D367-L371 PolarHBondContact O-N 3.35Å; D367-L371 VanDerWaalsContact O-N 3.12Å; I368-L371 WeakPolarHBondContact O-CB 3.26Å; I368-L371 PolarHBondContact O-N 3.32Å; Y369-L371 VanDerWaalsContact C-N 3.3Å; Y369-L371 PolarHBondContact O-N 2.96Å; L371-L375 WeakPolarHBondContact O-CB 3.2Å; L371-L375 PolarHBondContact O-N 2.99Å
372	I	89.4	Confident	88.4	Confident	0 Å²	0	26.8 Å²	26.8	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-64.8	-42.3	176.1	-72	166.9	0	0	0	111	V47 I124 V224 F227 I368 Y369 S370 L375 G376	V47-I372 HydrophobicContact CG1-CD1 3.81Å; I124-I372 HydrophobicContact CD1-CG1 3.71Å; I124-I372 HydrophobicContact CG1-CG1 4.18Å; I124-I372 HydrophobicContact CG2-CD1 4.16Å; I124-I372 HydrophobicContact CG2-CG1 4.04Å; V224-I372 HydrophobicContact CB-CG2 4.35Å; V224-I372 HydrophobicContact CG2-CG2 3.93Å; F227-I372 HydrophobicContact CB-CG2 4.01Å; F227-I372 HydrophobicContact CD1-CD1 4.21Å; F227-I372 HydrophobicContact CD1-CG1 4.35Å; F227-I372 HydrophobicContact CE1-CD1 4.46Å; F227-I372 HydrophobicContact CG-CG1 4.33Å; F227-I372 HydrophobicContact CG-CG2 4.35Å; I368-I372 HydrophobicContact CG2-CD1 3.82Å; I368-I372 HydrophobicContact CG2-CG1 4.45Å; I368-I372 VanDerWaalsContact O-CG1 3.27Å; I368-I372 WeakPolarHBondContact O-CG1 3.41Å; I368-I372 PolarHBondContact O-N 3.15Å; Y369-I372 HydrophobicContact CD1-CD1 4.25Å; Y369-I372 WeakPolarHBondContact O-CB 3.29Å; Y369-I372 PolarHBondContact O-N 3.29Å; Y369-I372 VanDerWaalsContact O-N 3.12Å; S370-I372 VanDerWaalsContact C-N 3.34Å; S370-I372 PolarHBondContact O-N 3.35Å; I372-L375 PolarHBondContact O-N 2.96Å; I372-G376 WeakPolarHBondContact O-CA 3.41Å; I372-G376 PolarHBondContact O-N 2.89Å
373	T	88.2	Confident	88.4	Confident	15 Å²	15	25.9 Å²	25.9	9%	0.092	14%	0.144	C	C	.	.	H	α-helix	trans	-65	-47.1	178.1	-60.2	0	0	0	0	111.3	Y223 Y369 S370 G376 F377 A429 E432	Y223-T373 HydrophobicContact CD2-CG2 4.25Å; Y369-T373 PolarHBondContact O-N 3.04Å; Y369-T373 PolarHBondContact O-OG1 3.08Å; S370-T373 PolarHBondContact O-N 3.46Å; T373-G376 PolarHBondContact O-N 3.18Å; T373-F377 PolarHBondContact O-N 2.84Å; T373-A429 HydrophobicContact CG2-CB 3.62Å; T373-E432 HydrophobicContact CG2-CB 4.29Å
374	Y	87.5	Confident	88.4	Confident	13 Å²	13	26 Å²	26	5%	0.051	15%	0.146	C	C	.	.	H	α-helix	trans	-59	-48.2	174.5	161.8	-100	0	0	0	112	V116 Y362 S370 G376 F377 V378 L435 G436 I439	V116-Y374 HydrophobicContact CG1-CD1 4.37Å; V116-Y374 HydrophobicContact CG1-CE1 3.35Å; V116-Y374 HydrophobicContact CG1-CE2 4.46Å; V116-Y374 WeakPolarHBondContact CG1-OH 3.35Å; V116-Y374 WeakPolarHBondContact CG2-OH 3.5Å; Y362-Y374 HydrophobicContact CE1-CD1 4.47Å; Y362-Y374 AromaticContact CE1-CE1 3.61Å; Y362-Y374 HydrophobicContact CE1-CE1 3.61Å; Y362-Y374 PolarHBondContact OH-OH 2.77Å; S370-Y374 WeakPolarHBondContact O-CB 3.45Å; S370-Y374 PolarHBondContact O-N 3.2Å; Y374-G376 VanDerWaalsContact C-N 3.34Å; Y374-G376 PolarHBondContact O-N 2.94Å; Y374-F377 PolarHBondContact O-N 3.25Å; Y374-V378 HydrophobicContact CE2-CG2 4.3Å; Y374-V378 PolarHBondContact O-N 3.39Å; Y374-L435 HydrophobicContact CD2-CB 4.23Å; Y374-L435 HydrophobicContact CE2-CB 4.29Å; Y374-G436 VanDerWaalsContact CE2-CA 3.44Å; Y374-I439 HydrophobicContact CE2-CD1 3.93Å; Y374-I439 WeakPolarHBondContact OH-CD1 3.31Å
375	L	90.7	Very high	88.7	Confident	2 Å²	2	21.7 Å²	21.7	1%	0.01	13%	0.131	C	C	.	.	H	α-helix	trans	-60	-45.7	175.8	172.3	62.9	0	0	0	111	A117 A120 S121 I124 F227 L371 I372 F377 V378 Q379	A117-L375 VanDerWaalsContact CA-CD1 3.42Å; A117-L375 HydrophobicContact CB-CD1 3.89Å; A117-L375 WeakPolarHBondContact O-CD1 3.5Å; A120-L375 HydrophobicContact CB-CD1 4.42Å; S121-L375 WeakPolarHBondContact OG-CD2 3.45Å; I124-L375 HydrophobicContact CD1-CB 4.48Å; I124-L375 HydrophobicContact CD1-CD2 3.7Å; F227-L375 HydrophobicContact CD2-CD2 3.73Å; F227-L375 HydrophobicContact CE2-CD2 3.8Å; L371-L375 WeakPolarHBondContact O-CB 3.2Å; L371-L375 PolarHBondContact O-N 2.99Å; I372-L375 PolarHBondContact O-N 2.96Å; L375-F377 VanDerWaalsContact C-N 3.33Å; L375-F377 PolarHBondContact O-N 2.6Å; L375-V378 PolarHBondContact O-N 3.24Å; L375-Q379 HydrophobicContact CD1-CB 4.36Å; L375-Q379 WeakPolarHBondContact O-CB 3.46Å; L375-Q379 PolarHBondContact O-N 2.77Å
376	G	90.4	Very high	89.3	Confident	2 Å²	2	18.4 Å²	18.4	2%	0.021	11%	0.111	C	C	.	.	H	α-helix	trans	-57	-47.2	179	0	0	0	0	0	111.3	I372 T373 Y374 V378 W380	I372-G376 WeakPolarHBondContact O-CA 3.41Å; I372-G376 PolarHBondContact O-N 2.89Å; T373-G376 PolarHBondContact O-N 3.18Å; Y374-G376 VanDerWaalsContact C-N 3.34Å; Y374-G376 PolarHBondContact O-N 2.94Å; G376-V378 PolarHBondContact O-N 2.94Å; G376-W380 VanDerWaalsContact O-CB 3.3Å; G376-W380 WeakPolarHBondContact O-CB 3.29Å; G376-W380 PolarHBondContact O-N 2.75Å
377	F	91.7	Very high	90.4	Very high	3 Å²	3	16.6 Å²	16.6	1%	0.013	9%	0.093	C	C	.	.	H	α-helix	trans	-55.9	-55.4	175.5	178.5	-91.5	0	0	0	111.8	Y223 T373 Y374 L375 L381 V422 A425 F426 V437	Y223-F377 HydrophobicContact CE2-CB 4.27Å; T373-F377 PolarHBondContact O-N 2.84Å; Y374-F377 PolarHBondContact O-N 3.25Å; L375-F377 VanDerWaalsContact C-N 3.33Å; L375-F377 PolarHBondContact O-N 2.6Å; F377-L381 HydrophobicContact CE1-CD2 4.1Å; F377-L381 HydrophobicContact CZ-CD2 4.26Å; F377-L381 WeakPolarHBondContact O-CB 3.3Å; F377-L381 PolarHBondContact O-N 3.47Å; F377-V422 HydrophobicContact CE2-CG1 3.91Å; F377-V422 HydrophobicContact CZ-CG1 4.41Å; F377-A425 HydrophobicContact CD2-CB 3.89Å; F377-A425 HydrophobicContact CE2-CB 4.48Å; F377-F426 HydrophobicContact CE2-CD2 4.32Å; F377-F426 AromaticContact CE2-CE2 3.61Å; F377-F426 HydrophobicContact CE2-CE2 3.61Å; F377-F426 AromaticContact CE2-CZ 3.84Å; F377-F426 HydrophobicContact CE2-CZ 3.84Å; F377-F426 AromaticContact CZ-CE2 3.81Å; F377-F426 HydrophobicContact CZ-CE2 3.81Å; F377-F426 AromaticContact CZ-CZ 3.65Å; F377-F426 HydrophobicContact CZ-CZ 3.65Å; F377-V437 HydrophobicContact CE1-CG2 3.73Å; F377-V437 HydrophobicContact CZ-CG2 3.75Å
378	V	92.4	Very high	91	Very high	2 Å²	2	14.6 Å²	14.6	1%	0.012	8%	0.084	C	C	.	.	H	α-helix	trans	-65.4	-45.8	-174.9	172.9	0	0	0	0	111.5	V116 Y374 L375 G376 A382 I440	V116-V378 HydrophobicContact CB-CG1 4.1Å; V116-V378 HydrophobicContact CG1-CB 4.06Å; V116-V378 HydrophobicContact CG1-CG1 3.86Å; V116-V378 HydrophobicContact CG1-CG2 4.07Å; Y374-V378 HydrophobicContact CE2-CG2 4.3Å; Y374-V378 PolarHBondContact O-N 3.39Å; L375-V378 PolarHBondContact O-N 3.24Å; G376-V378 PolarHBondContact O-N 2.94Å; V378-A382 VanDerWaalsContact O-CB 3.31Å; V378-A382 WeakPolarHBondContact O-CB 3.16Å; V378-A382 PolarHBondContact O-N 3.12Å; V378-A382 VanDerWaalsContact O-N 3.07Å; V378-I440 HydrophobicContact CB-CD1 4.49Å; V378-I440 HydrophobicContact CG1-CD1 4.06Å; V378-I440 HydrophobicContact CG1-CG1 4.17Å; V378-I440 HydrophobicContact CG2-CD1 4.15Å; V378-I440 HydrophobicContact CG2-CG1 4.43Å
379	Q	91.5	Very high	91.5	Very high	11 Å²	11	14.2 Å²	14.2	5%	0.051	8%	0.082	C	C	.	.	H	α-helix	trans	-68.1	-47.6	-176.2	-175.6	174.2	-3.2	0	0	111.5	S230 L375 A382 I383	S230-Q379 PolarHBondContact OG-NE2 3.36Å; L375-Q379 HydrophobicContact CD1-CB 4.36Å; L375-Q379 WeakPolarHBondContact O-CB 3.46Å; L375-Q379 PolarHBondContact O-N 2.77Å; Q379-A382 PolarHBondContact O-N 3.44Å; Q379-I383 HydrophobicContact CG-CD1 3.86Å; Q379-I383 VanDerWaalsContact O-CG1 3.32Å; Q379-I383 WeakPolarHBondContact O-CG1 3.48Å; Q379-I383 PolarHBondContact O-N 2.81Å
380	W	91.1	Very high	91.9	Very high	2 Å²	2	12 Å²	12	1%	0.008	7%	0.074	C	C	.	.	H	α-helix	trans	-76.2	-30.2	-176.4	-60.5	117.1	0	0	0	112.3	F72 Y223 L226 W232 G376 I383 G384 Y414 T418	F72-W380 HydrophobicContact CE1-CE3 4.09Å; F72-W380 HydrophobicContact CE1-CZ3 4.42Å; Y223-W380 AromaticContact CD1-CD1 3.65Å; Y223-W380 HydrophobicContact CE1-CB 4.33Å; Y223-W380 AromaticContact CE1-CD1 3.91Å; Y223-W380 HydrophobicContact CE1-CG 4.46Å; L226-W380 HydrophobicContact CB-CD2 4.35Å; L226-W380 VanDerWaalsContact CB-CE2 3.44Å; L226-W380 HydrophobicContact CB-CH2 4.28Å; L226-W380 HydrophobicContact CB-CZ2 3.46Å; L226-W380 VanDerWaalsContact CB-CZ2 3.46Å; L226-W380 HydrophobicContact CD1-CD2 3.79Å; L226-W380 HydrophobicContact CD1-CE3 4.32Å; L226-W380 HydrophobicContact CD1-CG 4Å; L226-W380 HydrophobicContact CD1-CZ2 4.3Å; L226-W380 HydrophobicContact CD2-CH2 4.48Å; L226-W380 HydrophobicContact CD2-CZ2 4.43Å; L226-W380 HydrophobicContact CG-CZ2 4.28Å; L226-W380 WeakPolarHBondContact O-CZ2 3.42Å; W232-W380 HydrophobicContact CZ2-CZ3 4.31Å; G376-W380 VanDerWaalsContact O-CB 3.3Å; G376-W380 WeakPolarHBondContact O-CB 3.29Å; G376-W380 PolarHBondContact O-N 2.75Å; W380-I383 HydrophobicContact CE3-CB 4.28Å; W380-I383 HydrophobicContact CE3-CD1 3.72Å; W380-I383 HydrophobicContact CE3-CG2 4.42Å; W380-I383 HydrophobicContact CH2-CD1 4.08Å; W380-I383 HydrophobicContact CZ3-CD1 3.49Å; W380-I383 VanDerWaalsContact CZ3-CD1 3.49Å; W380-I383 HydrophobicContact CZ3-CG2 4.43Å; W380-G384 PolarHBondContact O-N 2.96Å; W380-Y414 WeakPolarHBondContact CZ3-OH 3.39Å; W380-T418 VanDerWaalsContact O-CG2 3.29Å; W380-T418 WeakPolarHBondContact O-CG2 3.31Å
381	L	92.6	Very high	92.4	Very high	54 Å²	54	12.3 Å²	12.3	28%	0.283	7%	0.072	S	C	.	.	H	α-helix	trans	-59.1	-48.9	166.4	177.7	64.5	0	0	0	110.8	F377 I383 G384 V385 V422 I440	F377-L381 HydrophobicContact CE1-CD2 4.1Å; F377-L381 HydrophobicContact CZ-CD2 4.26Å; F377-L381 WeakPolarHBondContact O-CB 3.3Å; F377-L381 PolarHBondContact O-N 3.47Å; L381-I383 PolarHBondContact O-N 3.06Å; L381-G384 PolarHBondContact O-N 3.39Å; L381-V385 WeakPolarHBondContact O-CG2 3.39Å; L381-V385 PolarHBondContact O-N 2.86Å; L381-V422 HydrophobicContact CB-CG2 4.23Å; L381-V422 HydrophobicContact CD1-CG1 4.48Å; L381-V422 HydrophobicContact CD1-CG2 3.99Å; L381-I440 HydrophobicContact CD2-CD1 4.18Å
382	A	92.4	Very high	92.8	Very high	11 Å²	11	14.3 Å²	14.3	9%	0.091	8%	0.084	C	C	.	.	H	α-helix	trans	-62.2	-44.1	-179.3	0	0	0	0	0	112.4	V378 Q379 V385 C386	V378-A382 VanDerWaalsContact O-CB 3.31Å; V378-A382 WeakPolarHBondContact O-CB 3.16Å; V378-A382 PolarHBondContact O-N 3.12Å; V378-A382 VanDerWaalsContact O-N 3.07Å; Q379-A382 PolarHBondContact O-N 3.44Å; A382-V385 PolarHBondContact O-N 3.29Å; A382-C386 PolarHBondContact O-N 3.45Å; A382-C386 PolarHBondContact O-SG 2.6Å
383	I	92.3	Very high	93.1	Very high	1 Å²	1	14.5 Å²	14.5	1%	0.005	9%	0.085	C	C	.	.	H	α-helix	trans	-67.8	-38.7	176.8	-66.3	171.3	0	0	0	110.8	Y80 W232 Q379 W380 L381 V385 C386 V387 Y414	Y80-I383 HydrophobicContact CE2-CG2 3.87Å; W232-I383 HydrophobicContact CH2-CG2 4Å; W232-I383 HydrophobicContact CZ2-CD1 4.48Å; W232-I383 HydrophobicContact CZ2-CG2 4.02Å; Q379-I383 HydrophobicContact CG-CD1 3.86Å; Q379-I383 VanDerWaalsContact O-CG1 3.32Å; Q379-I383 WeakPolarHBondContact O-CG1 3.48Å; Q379-I383 PolarHBondContact O-N 2.81Å; W380-I383 HydrophobicContact CE3-CB 4.28Å; W380-I383 HydrophobicContact CE3-CD1 3.72Å; W380-I383 HydrophobicContact CE3-CG2 4.42Å; W380-I383 HydrophobicContact CH2-CD1 4.08Å; W380-I383 HydrophobicContact CZ3-CD1 3.49Å; W380-I383 VanDerWaalsContact CZ3-CD1 3.49Å; W380-I383 HydrophobicContact CZ3-CG2 4.43Å; L381-I383 PolarHBondContact O-N 3.06Å; I383-V385 VanDerWaalsContact C-N 3.33Å; I383-V385 PolarHBondContact O-N 2.86Å; I383-C386 CarbonylContact O-C 3.54Å; I383-C386 WeakPolarHBondContact O-CA 3.12Å; I383-C386 WeakPolarHBondContact O-CB 3.29Å; I383-C386 PolarHBondContact O-N 3.01Å; I383-C386 VanDerWaalsContact O-N 3.1Å; I383-V387 HydrophobicContact CG2-CG2 4.36Å; I383-V387 WeakPolarHBondContact O-CG2 3.44Å; I383-V387 PolarHBondContact O-N 2.79Å; I383-Y414 HydrophobicContact CG2-CE1 4Å; I383-Y414 VanDerWaalsContact CG2-OH 3.22Å; I383-Y414 WeakPolarHBondContact CG2-OH 3.37Å
384	G	95	Very high	93.3	Very high	6 Å²	6	15.7 Å²	15.7	6%	0.062	9%	0.088	C	C	.	.	H	α-helix	trans	-58.2	-43.7	173.9	0	0	0	0	0	112.7	W380 L381 V387 S388	W380-G384 PolarHBondContact O-N 2.96Å; L381-G384 PolarHBondContact O-N 3.39Å; G384-V387 PolarHBondContact O-N 2.85Å; G384-S388 WeakPolarHBondContact O-CB 3.22Å; G384-S388 PolarHBondContact O-N 3.33Å
385	V	94.6	Very high	93.6	Very high	58 Å²	58	21.5 Å²	21.5	35%	0.352	12%	0.118	S	C	.	.	H	α-helix	trans	-60.8	-45.1	172.6	172.8	0	0	0	0	110.4	F101 L381 A382 I383 V387 S388 I389	F101-V385 HydrophobicContact CD2-CG1 4.44Å; F101-V385 HydrophobicContact CE2-CG1 3.9Å; L381-V385 WeakPolarHBondContact O-CG2 3.39Å; L381-V385 PolarHBondContact O-N 2.86Å; A382-V385 PolarHBondContact O-N 3.29Å; I383-V385 VanDerWaalsContact C-N 3.33Å; I383-V385 PolarHBondContact O-N 2.86Å; V385-V387 PolarHBondContact O-N 3.38Å; V385-S388 WeakPolarHBondContact O-CB 3.47Å; V385-S388 PolarHBondContact O-N 3.15Å; V385-S388 PolarHBondContact O-OG 3.07Å; V385-I389 PolarHBondContact O-N 3.35Å
386	C	94.2	Very high	93.8	Very high	0 Å²	0	25.9 Å²	25.9	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-59.7	-45.7	175.4	-72.1	0	0	0	0	112.5	Y80 L83 V97 A382 I383 S388 I389	Y80-C386 HydrophobicContact CE2-CB 3.77Å; Y80-C386 WeakPolarHBondContact OH-CB 3.48Å; L83-C386 WeakPolarHBondContact CD1-O 3.3Å; V97-C386 WeakPolarHBondContact CG2-SG 3.47Å; A382-C386 PolarHBondContact O-N 3.45Å; A382-C386 PolarHBondContact O-SG 2.6Å; I383-C386 CarbonylContact O-C 3.54Å; I383-C386 WeakPolarHBondContact O-CA 3.12Å; I383-C386 WeakPolarHBondContact O-CB 3.29Å; I383-C386 PolarHBondContact O-N 3.01Å; I383-C386 VanDerWaalsContact O-N 3.1Å; C386-S388 VanDerWaalsContact C-N 3.29Å; C386-S388 PolarHBondContact O-N 2.88Å; C386-I389 WeakPolarHBondContact O-CB 3.22Å; C386-I389 WeakPolarHBondContact O-CG1 3.21Å; C386-I389 PolarHBondContact O-N 2.92Å; C386-I389 VanDerWaalsContact O-N 3.1Å
387	V	95.5	Very high	93.8	Very high	0 Å²	0	28.6 Å²	28.6	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-65.7	-33.7	178.6	175.6	0	0	0	0	111.6	C79 Y80 I383 G384 V385 I389 V390 A411 Y414 V415	C79-V387 HydrophobicContact CB-CG1 3.88Å; C79-V387 HydrophobicContact CB-CG2 4.21Å; Y80-V387 HydrophobicContact CD2-CG2 4.03Å; Y80-V387 HydrophobicContact CE2-CG2 3.86Å; I383-V387 HydrophobicContact CG2-CG2 4.36Å; I383-V387 WeakPolarHBondContact O-CG2 3.44Å; I383-V387 PolarHBondContact O-N 2.79Å; G384-V387 PolarHBondContact O-N 2.85Å; V385-V387 PolarHBondContact O-N 3.38Å; V387-I389 PolarHBondContact O-N 3.26Å; V387-I389 VanDerWaalsContact O-N 3.15Å; V387-V390 WeakPolarHBondContact O-CB 3.43Å; V387-V390 PolarHBondContact O-N 3.11Å; V387-A411 HydrophobicContact CG1-CB 4.06Å; V387-Y414 HydrophobicContact CB-CD1 3.73Å; V387-Y414 HydrophobicContact CB-CE1 4.16Å; V387-Y414 HydrophobicContact CB-CG 4.46Å; V387-Y414 HydrophobicContact CG1-CD1 3.77Å; V387-Y414 HydrophobicContact CG1-CG 4.05Å; V387-Y414 HydrophobicContact CG2-CD1 3.63Å; V387-Y414 HydrophobicContact CG2-CE1 3.66Å; V387-Y414 HydrophobicContact CG2-CG 4.28Å; V387-V415 HydrophobicContact CG1-CG2 4.32Å
388	S	96.4	Very high	93.6	Very high	30 Å²	30	37.8 Å²	37.8	21%	0.21	19%	0.191	C	C	.	.	H	α-helix	trans	-59.6	-25.5	174.7	83.2	0	0	0	0	112.9	G384 V385 C386 V390 I391 V392	G384-S388 WeakPolarHBondContact O-CB 3.22Å; G384-S388 PolarHBondContact O-N 3.33Å; V385-S388 WeakPolarHBondContact O-CB 3.47Å; V385-S388 PolarHBondContact O-N 3.15Å; V385-S388 PolarHBondContact O-OG 3.07Å; C386-S388 VanDerWaalsContact C-N 3.29Å; C386-S388 PolarHBondContact O-N 2.88Å; S388-V390 PolarHBondContact O-N 3.4Å; S388-I391 WeakPolarHBondContact O-CA 3.14Å; S388-I391 WeakPolarHBondContact O-CB 3.45Å; S388-I391 PolarHBondContact O-N 3.29Å; S388-V392 PolarHBondContact O-N 3.33Å
389	I	95.5	Very high	93.5	Very high	0 Å²	0	45.1 Å²	45.1	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-61.2	-32.9	175.7	-60.7	169.9	0	0	0	111.3	L83 V97 A100 F101 V385 C386 V387 I391 V392 F393	L83-I389 HydrophobicContact CD1-CB 4.49Å; L83-I389 HydrophobicContact CD2-CB 4.28Å; L83-I389 HydrophobicContact CD2-CG2 3.87Å; V97-I389 HydrophobicContact CG2-CD1 4.03Å; A100-I389 HydrophobicContact CB-CB 4.3Å; A100-I389 HydrophobicContact CB-CD1 3.77Å; A100-I389 HydrophobicContact CB-CG1 3.74Å; A100-I389 HydrophobicContact CB-CG2 3.61Å; F101-I389 HydrophobicContact CD2-CG1 4.43Å; F101-I389 HydrophobicContact CE2-CD1 4.1Å; F101-I389 HydrophobicContact CE2-CG1 3.62Å; F101-I389 HydrophobicContact CZ-CG1 4.06Å; V385-I389 PolarHBondContact O-N 3.35Å; C386-I389 WeakPolarHBondContact O-CB 3.22Å; C386-I389 WeakPolarHBondContact O-CG1 3.21Å; C386-I389 PolarHBondContact O-N 2.92Å; C386-I389 VanDerWaalsContact O-N 3.1Å; V387-I389 PolarHBondContact O-N 3.26Å; V387-I389 VanDerWaalsContact O-N 3.15Å; I389-I391 PolarHBondContact O-N 2.89Å; I389-V392 PolarHBondContact O-N 2.9Å; I389-F393 HydrophobicContact CG2-CD1 3.9Å; I389-F393 HydrophobicContact CG2-CD2 3.59Å; I389-F393 HydrophobicContact CG2-CE1 3.73Å; I389-F393 HydrophobicContact CG2-CE2 3.38Å; I389-F393 HydrophobicContact CG2-CG 3.84Å; I389-F393 HydrophobicContact CG2-CZ 3.47Å; I389-F393 VanDerWaalsContact CG2-CZ 3.47Å; I389-F393 WeakPolarHBondContact O-CB 3.3Å; I389-F393 WeakPolarHBondContact O-CG 3.21Å; I389-F393 PolarHBondContact O-N 3.35Å
390	V	95.6	Very high	93.4	Very high	0 Å²	0	48.4 Å²	48.4	0%	0	25%	0.245	C	C	.	.	H	α-helix	trans	-59	-41.8	174.8	177.8	0	0	0	0	110.3	C79 L83 V387 S388 R394 A411	C79-V390 HydrophobicContact CB-CG2 4.11Å; L83-V390 HydrophobicContact CD1-CG2 4.02Å; L83-V390 HydrophobicContact CD2-CG2 3.82Å; L83-V390 HydrophobicContact CG-CG2 3.71Å; V387-V390 WeakPolarHBondContact O-CB 3.43Å; V387-V390 PolarHBondContact O-N 3.11Å; S388-V390 PolarHBondContact O-N 3.4Å; V390-R394 WeakPolarHBondContact O-CG 3.45Å; V390-R394 PolarHBondContact O-N 2.69Å; V390-R394 VanDerWaalsContact O-N 3.13Å; V390-A411 HydrophobicContact CB-CB 4.16Å; V390-A411 HydrophobicContact CG1-CB 4.15Å
391	I	96.3	Very high	93.3	Very high	46 Å²	46	53 Å²	53	24%	0.236	28%	0.275	C	S	.	.	H	α-helix	trans	-67.9	-46.5	177.1	-53.8	175.8	0	0	0	109.9	S388 I389 F393 R394 A411 I412 V415	S388-I391 WeakPolarHBondContact O-CA 3.14Å; S388-I391 WeakPolarHBondContact O-CB 3.45Å; S388-I391 PolarHBondContact O-N 3.29Å; I389-I391 PolarHBondContact O-N 2.89Å; I391-F393 PolarHBondContact O-N 2.93Å; I391-R394 WeakPolarHBondContact O-CB 3.43Å; I391-R394 PolarHBondContact O-N 3.47Å; I391-A411 HydrophobicContact CD1-CB 4.27Å; I391-A411 HydrophobicContact CG1-CB 3.83Å; I391-I412 HydrophobicContact CD1-CG1 4.09Å; I391-V415 HydrophobicContact CD1-CG2 4.1Å
392	V	95.6	Very high	93.3	Very high	44 Å²	44	52.8 Å²	52.8	27%	0.267	27%	0.271	S	S	.	.	H	α-helix	trans	-59.4	-47.9	178.3	175.1	0	0	0	0	111.2	F101 S388 I389 R394 I395 T396	F101-V392 HydrophobicContact CE1-CG2 4.34Å; F101-V392 HydrophobicContact CZ-CG2 4.29Å; S388-V392 PolarHBondContact O-N 3.33Å; I389-V392 PolarHBondContact O-N 2.9Å; V392-R394 VanDerWaalsContact C-N 3.27Å; V392-R394 PolarHBondContact O-N 2.87Å; V392-I395 WeakPolarHBondContact O-CA 3.16Å; V392-I395 WeakPolarHBondContact O-CB 3.16Å; V392-I395 PolarHBondContact O-N 2.96Å; V392-T396 HydrophobicContact CG1-CG2 3.96Å; V392-T396 PolarHBondContact O-N 3.16Å; V392-T396 PolarHBondContact O-OG1 2.9Å; V392-T396 VanDerWaalsContact O-OG1 3.11Å
393	F	94.9	Very high	93.2	Very high	4 Å²	4	54.6 Å²	54.6	2%	0.018	28%	0.282	C	S	.	.	H	α-helix	trans	-69.3	-21.4	-179.4	-75.3	-2.7	0	0	0	113.8	L83 M86 I87 E99 A100 I389 I391 I395 K397 R402	L83-F393 HydrophobicContact CD2-CD2 4.13Å; L83-F393 HydrophobicContact CD2-CE2 4.31Å; M86-F393 HydrophobicContact CE-CB 4.32Å; M86-F393 HydrophobicContact CE-CD2 3.75Å; M86-F393 HydrophobicContact CE-CE2 4.34Å; M86-F393 HydrophobicContact CE-CG 4.2Å; M86-F393 HydrophobicContact SD-CD2 3.99Å; I87-F393 HydrophobicContact CD1-CE2 3.74Å; I87-F393 HydrophobicContact CD1-CZ 4.24Å; E99-F393 HydrophobicContact CG-CZ 4.34Å; A100-F393 HydrophobicContact CB-CE1 3.67Å; A100-F393 HydrophobicContact CB-CZ 3.73Å; I389-F393 HydrophobicContact CG2-CD1 3.9Å; I389-F393 HydrophobicContact CG2-CD2 3.59Å; I389-F393 HydrophobicContact CG2-CE1 3.73Å; I389-F393 HydrophobicContact CG2-CE2 3.38Å; I389-F393 HydrophobicContact CG2-CG 3.84Å; I389-F393 HydrophobicContact CG2-CZ 3.47Å; I389-F393 VanDerWaalsContact CG2-CZ 3.47Å; I389-F393 WeakPolarHBondContact O-CB 3.3Å; I389-F393 WeakPolarHBondContact O-CG 3.21Å; I389-F393 PolarHBondContact O-N 3.35Å; I391-F393 PolarHBondContact O-N 2.93Å; F393-I395 PolarHBondContact O-N 3.37Å; F393-K397 HydrophobicContact CB-CB 4.46Å; F393-K397 HydrophobicContact CD1-CD 4.26Å; F393-K397 HydrophobicContact CD1-CG 4.44Å; F393-K397 HydrophobicContact CE1-CD 4.27Å; F393-K397 HydrophobicContact CG-CD 4.47Å; F393-K397 CarbonylContact O-C 3.57Å; F393-K397 VanDerWaalsContact O-C 3.23Å; F393-K397 WeakPolarHBondContact O-CA 3.49Å; F393-K397 PolarHBondContact O-N 3.46Å; F393-R402 PolarHBondContact O-NH2 2.89Å
394	R	94.1	Very high	93.2	Very high	40 Å²	40	54.9 Å²	54.9	15%	0.151	28%	0.283	C	S	.	.	H	α-helix	trans	-62.9	-32.1	168.1	-71	-91.2	-177.3	-81.5	-3.9	111.4	E82 V390 I391 V392 A406 I408	E82-R394 IonicContact OE1-CZ 3.71Å; E82-R394 IonicContact OE1-NH1 3.14Å; E82-R394 PolarHBondContact OE1-NH1 3.47Å; E82-R394 IonicContact OE1-NH2 3.89Å; E82-R394 PolarHBondContact OE1-NH2 3.41Å; E82-R394 IonicContact OE2-CZ 2.7Å; E82-R394 IonicContact OE2-NH1 3.6Å; E82-R394 IonicContact OE2-NH2 2.78Å; E82-R394 PolarHBondContact OE2-NH2 3.45Å; V390-R394 WeakPolarHBondContact O-CG 3.45Å; V390-R394 PolarHBondContact O-N 2.69Å; V390-R394 VanDerWaalsContact O-N 3.13Å; I391-R394 WeakPolarHBondContact O-CB 3.43Å; I391-R394 PolarHBondContact O-N 3.47Å; V392-R394 VanDerWaalsContact C-N 3.27Å; V392-R394 PolarHBondContact O-N 2.87Å; R394-A406 PolarHBondContact NH2-O 3.25Å; R394-I408 HydrophobicContact CB-CD1 4.2Å; R394-I408 HydrophobicContact CG-CD1 3.9Å
395	I	93.6	Very high	93.1	Very high	136 Å²	136	61.3 Å²	61.3	70%	0.697	31%	0.31	S	S	*	.	H	α-helix	trans	-90.6	-51.5	-178.8	-55.9	171	0	0	0	110.5	V392 F393	V392-I395 WeakPolarHBondContact O-CA 3.16Å; V392-I395 WeakPolarHBondContact O-CB 3.16Å; V392-I395 PolarHBondContact O-N 2.96Å; F393-I395 PolarHBondContact O-N 3.37Å
396	T	93.9	Very high	93.1	Very high	94 Å²	94	58.6 Å²	58.6	58%	0.577	29%	0.293	S	S	*	.	H	α-helix	trans	-82.9	-33.3	-171.4	60.2	0	0	0	0	113.9	V392	V392-T396 HydrophobicContact CG1-CG2 3.96Å; V392-T396 PolarHBondContact O-N 3.16Å; V392-T396 PolarHBondContact O-OG1 2.9Å; V392-T396 VanDerWaalsContact O-OG1 3.11Å
397	K	90.8	Very high	93.1	Very high	58 Å²	58	61.6 Å²	61.6	25%	0.252	31%	0.313	S	S	.	.	T	Hydrogen-bonded Turn	trans	-119.5	48.7	-177.7	-67.5	-171.5	176.9	-176.6	0	111.3	M86 E99 F393 N399 H400 R402	M86-K397 HydrophobicContact CE-CB 3.79Å; M86-K397 HydrophobicContact CE-CD 3.69Å; M86-K397 HydrophobicContact CE-CG 4.36Å; E99-K397 IonicContact OE1-NZ 2.94Å; E99-K397 PolarHBondContact OE1-NZ 3.33Å; F393-K397 HydrophobicContact CB-CB 4.46Å; F393-K397 HydrophobicContact CD1-CD 4.26Å; F393-K397 HydrophobicContact CD1-CG 4.44Å; F393-K397 HydrophobicContact CE1-CD 4.27Å; F393-K397 HydrophobicContact CG-CD 4.47Å; F393-K397 CarbonylContact O-C 3.57Å; F393-K397 VanDerWaalsContact O-C 3.23Å; F393-K397 WeakPolarHBondContact O-CA 3.49Å; F393-K397 PolarHBondContact O-N 3.46Å; K397-N399 VanDerWaalsContact C-N 3.33Å; K397-N399 PolarHBondContact O-N 3.49Å; K397-H400 HydrophobicContact CB-CB 4.27Å; K397-H400 PolarHBondContact O-N 3.41Å; K397-R402 PolarHBondContact O-NH2 2.86Å
398	R	88.5	Confident	93.1	Very high	197 Å²	197	65.1 Å²	65.1	74%	0.743	33%	0.331	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.3	-43	-172.5	-171.9	174.9	177.5	174.6	-0.9	113.8	R402	R398-R402 PolarHBondContact O-NH1 3.22Å
399	N	89	Confident	93.1	Very high	155 Å²	155	68.6 Å²	68.6	83%	0.829	35%	0.346	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.1	0	-172.6	-62.2	-18.5	0	0	0	114.5	K397	K397-N399 VanDerWaalsContact C-N 3.33Å; K397-N399 PolarHBondContact O-N 3.49Å
400	H	89	Confident	93.1	Very high	81 Å²	81	71.8 Å²	71.8	38%	0.375	36%	0.361	S	S	.	.	S	Bend	trans	-68.1	136.7	179.5	-159.5	-78.7	0	0	0	110.4	M86 K397 R402	M86-H400 HydrophobicContact CE-CB 3.69Å; K397-H400 HydrophobicContact CB-CB 4.27Å; K397-H400 PolarHBondContact O-N 3.41Å; H400-R402 PolarHBondContact O-N 3.18Å; H400-R402 PolarHBondContact O-NH1 3.16Å
401	P	90	Very high	93.2	Very high	98 Å²	98	71.8 Å²	71.8	64%	0.636	36%	0.361	S	S	*	.			trans	-60.4	136.7	175.2	21	-30	0	0	0	110.6
402	R	92.3	Very high	93.2	Very high	49 Å²	49	72.9 Å²	72.9	19%	0.185	37%	0.366	C	S	.	.			trans	-128.2	93.2	-179.4	-67	178.1	-176	98	-8.1	108.7	E82 M86 F393 K397 R398 H400 V404	E82-R402 VanDerWaalsContact OE1-CD 3.32Å; E82-R402 WeakPolarHBondContact OE1-CD 3.31Å; E82-R402 IonicContact OE1-NE 3.66Å; E82-R402 PolarHBondContact OE1-NE 3.14Å; M86-R402 HydrophobicContact SD-CG 4.18Å; F393-R402 PolarHBondContact O-NH2 2.89Å; K397-R402 PolarHBondContact O-NH2 2.86Å; R398-R402 PolarHBondContact O-NH1 3.22Å; H400-R402 PolarHBondContact O-N 3.18Å; H400-R402 PolarHBondContact O-NH1 3.16Å; R402-V404 PolarHBondContact O-N 3.14Å
403	P	91.2	Very high	93.3	Very high	49 Å²	49	73.7 Å²	73.7	32%	0.318	37%	0.368	S	S	.	.	S	Bend	trans	-58.6	-40.2	-178.5	-24.5	34.7	0	0	0	112.2	T85 R246	T85-P403 WeakPolarHBondContact O-CD 3.35Å; T85-P403 WeakPolarHBondContact O-CG 3.31Å; R246-P403 HydrophobicContact CB-CB 4.29Å; R246-P403 HydrophobicContact CG-CB 3.94Å; R246-P403 WeakPolarHBondContact CG-O 3.37Å; R246-P403 PolarHBondContact NE-O 3.31Å
404	V	91.9	Very high	93.5	Very high	7 Å²	7	73.5 Å²	73.5	4%	0.042	37%	0.368	C	S	.	.	S	Bend	trans	-111.9	131.5	167.6	179.4	0	0	0	0	107.7	Y78 A81 E82 T85 R246 P250 R402	Y78-V404 HydrophobicContact CE1-CG1 4.27Å; A81-V404 HydrophobicContact CB-CG1 4.2Å; E82-V404 WeakPolarHBondContact CG-O 3.37Å; T85-V404 HydrophobicContact CG2-CB 4.38Å; T85-V404 HydrophobicContact CG2-CG2 3.86Å; T85-V404 WeakPolarHBondContact OG1-CB 3.26Å; T85-V404 PolarHBondContact OG1-N 3.11Å; R246-V404 WeakPolarHBondContact O-CG2 3.02Å; P250-V404 HydrophobicContact CG-CG2 4.22Å; R402-V404 PolarHBondContact O-N 3.14Å
405	K	93.4	Very high	93.6	Very high	142 Å²	142	73 Å²	73	62%	0.617	37%	0.369	S	S	*	.			trans	-124.6	104.5	-179.5	-172.8	-177.9	178.3	-177	0	109
406	A	93.4	Very high	93.8	Very high	1 Å²	1	71.7 Å²	71.7	1%	0.008	36%	0.362	C	S	.	.			trans	-66.7	137	173.1	0	0	0	0	0	110.1	Y78 E82 R394 I408	Y78-A406 HydrophobicContact CD1-CB 3.76Å; Y78-A406 HydrophobicContact CE1-CB 4.21Å; E82-A406 HydrophobicContact CB-CB 4.3Å; E82-A406 WeakPolarHBondContact OE2-CB 3.48Å; E82-A406 PolarHBondContact OE2-N 2.93Å; R394-A406 PolarHBondContact NH2-O 3.25Å; A406-I408 PolarHBondContact O-N 3.2Å
407	P	95.1	Very high	93.9	Very high	62 Å²	62	69.9 Å²	69.9	40%	0.403	35%	0.349	S	S	.	.			trans	-53.1	129.5	166.1	-23.9	33.8	0	0	0	109.3	L409 F410	P407-L409 PolarHBondContact O-N 3Å; P407-L409 VanDerWaalsContact O-N 3.12Å; P407-F410 HydrophobicContact CB-CD1 4.09Å; P407-F410 HydrophobicContact CB-CE1 4.29Å; P407-F410 HydrophobicContact CB-CG 4.21Å; P407-F410 HydrophobicContact CG-CD1 4.35Å; P407-F410 HydrophobicContact CG-CD2 4.16Å; P407-F410 HydrophobicContact CG-CE1 4.21Å; P407-F410 HydrophobicContact CG-CE2 4.02Å; P407-F410 HydrophobicContact CG-CG 4.33Å; P407-F410 HydrophobicContact CG-CZ 4.04Å; P407-F410 WeakPolarHBondContact O-CB 3.22Å; P407-F410 PolarHBondContact O-N 2.85Å
408	I	94.7	Very high	94.2	Very high	75 Å²	75	67.4 Å²	67.4	39%	0.385	34%	0.338	S	S	.	.	H	α-helix	trans	-60.7	-28	-177.5	-163	166.3	0	0	0	111.9	R394 A406 F410 A411 I412	R394-I408 HydrophobicContact CB-CD1 4.2Å; R394-I408 HydrophobicContact CG-CD1 3.9Å; A406-I408 PolarHBondContact O-N 3.2Å; I408-F410 PolarHBondContact O-N 3.35Å; I408-A411 PolarHBondContact O-N 3.23Å; I408-I412 HydrophobicContact CG1-CD1 4.21Å; I408-I412 HydrophobicContact CG1-CG1 4.49Å; I408-I412 HydrophobicContact CG2-CD1 4.44Å; I408-I412 WeakPolarHBondContact O-CG1 3.37Å; I408-I412 PolarHBondContact O-N 2.94Å
409	L	96.5	Very high	94.5	Very high	102 Å²	102	62.4 Å²	62.4	53%	0.534	33%	0.326	S	S	.	.	H	α-helix	trans	-56.8	-36.1	174.1	-176	62.3	0	0	0	112.2	P407 I412 I413	P407-L409 PolarHBondContact O-N 3Å; P407-L409 VanDerWaalsContact O-N 3.12Å; L409-I412 PolarHBondContact O-N 3.37Å; L409-I413 HydrophobicContact CD1-CD1 3.95Å; L409-I413 HydrophobicContact CD1-CG1 4.1Å; L409-I413 HydrophobicContact CD2-CD1 4.36Å; L409-I413 HydrophobicContact CG-CD1 3.73Å; L409-I413 HydrophobicContact CG-CG1 4.3Å; L409-I413 WeakPolarHBondContact O-CB 3.05Å; L409-I413 VanDerWaalsContact O-CG1 3.25Å; L409-I413 WeakPolarHBondContact O-CG1 3.25Å; L409-I413 PolarHBondContact O-N 3.24Å
410	F	96.5	Very high	94.9	Very high	68 Å²	68	58.6 Å²	58.6	30%	0.298	30%	0.302	S	S	.	.	H	α-helix	trans	-65	-44.4	178.5	-69.4	5.5	0	0	0	110.8	L75 Y78 P407 I408 Y414	L75-F410 HydrophobicContact CD2-CB 3.96Å; L75-F410 HydrophobicContact CD2-CD1 3.71Å; L75-F410 HydrophobicContact CD2-CD2 3.79Å; L75-F410 HydrophobicContact CD2-CE1 4.09Å; L75-F410 HydrophobicContact CD2-CE2 4.16Å; L75-F410 HydrophobicContact CD2-CG 3.56Å; L75-F410 HydrophobicContact CD2-CZ 4.3Å; Y78-F410 HydrophobicContact CD1-CD2 4.34Å; Y78-F410 HydrophobicContact CG-CD2 4.47Å; P407-F410 HydrophobicContact CB-CD1 4.09Å; P407-F410 HydrophobicContact CB-CE1 4.29Å; P407-F410 HydrophobicContact CB-CG 4.21Å; P407-F410 HydrophobicContact CG-CD1 4.35Å; P407-F410 HydrophobicContact CG-CD2 4.16Å; P407-F410 HydrophobicContact CG-CE1 4.21Å; P407-F410 HydrophobicContact CG-CE2 4.02Å; P407-F410 HydrophobicContact CG-CG 4.33Å; P407-F410 HydrophobicContact CG-CZ 4.04Å; P407-F410 WeakPolarHBondContact O-CB 3.22Å; P407-F410 PolarHBondContact O-N 2.85Å; I408-F410 PolarHBondContact O-N 3.35Å; F410-Y414 VanDerWaalsContact O-CB 3.29Å; F410-Y414 WeakPolarHBondContact O-CB 3.37Å; F410-Y414 PolarHBondContact O-N 2.84Å
411	A	96.7	Very high	95.2	Very high	0 Å²	0	54.8 Å²	54.8	0%	0	29%	0.285	C	S	.	.	H	α-helix	trans	-65.3	-41.3	177	0	0	0	0	0	111.7	V387 V390 I391 I408 Y414 V415	V387-A411 HydrophobicContact CG1-CB 4.06Å; V390-A411 HydrophobicContact CB-CB 4.16Å; V390-A411 HydrophobicContact CG1-CB 4.15Å; I391-A411 HydrophobicContact CD1-CB 4.27Å; I391-A411 HydrophobicContact CG1-CB 3.83Å; I408-A411 PolarHBondContact O-N 3.23Å; A411-Y414 PolarHBondContact O-N 3.48Å; A411-V415 WeakPolarHBondContact O-CB 3.41Å; A411-V415 VanDerWaalsContact O-CG2 3.27Å; A411-V415 WeakPolarHBondContact O-CG2 3.32Å; A411-V415 PolarHBondContact O-N 3.43Å
412	I	97.2	Very high	95.3	Very high	69 Å²	69	51.1 Å²	51.1	35%	0.354	26%	0.261	S	S	.	.	H	α-helix	trans	-62.7	-50.6	177.9	-67.1	165.8	0	0	0	110.6	I391 I408 L409 Y414 V415 L416	I391-I412 HydrophobicContact CD1-CG1 4.09Å; I408-I412 HydrophobicContact CG1-CD1 4.21Å; I408-I412 HydrophobicContact CG1-CG1 4.49Å; I408-I412 HydrophobicContact CG2-CD1 4.44Å; I408-I412 WeakPolarHBondContact O-CG1 3.37Å; I408-I412 PolarHBondContact O-N 2.94Å; L409-I412 PolarHBondContact O-N 3.37Å; I412-Y414 VanDerWaalsContact C-N 3.3Å; I412-Y414 PolarHBondContact O-N 3.15Å; I412-V415 PolarHBondContact O-N 2.98Å; I412-L416 HydrophobicContact CG2-CD1 3.95Å; I412-L416 HydrophobicContact CG2-CG 4.37Å; I412-L416 WeakPolarHBondContact O-CB 3.26Å; I412-L416 VanDerWaalsContact O-CG 3.31Å; I412-L416 WeakPolarHBondContact O-CG 3.37Å; I412-L416 PolarHBondContact O-N 3.34Å
413	I	97.6	Very high	95.4	Very high	61 Å²	61	53.7 Å²	53.7	31%	0.313	28%	0.277	S	S	.	.	H	α-helix	trans	-58.7	-45.6	178.5	-69.6	170.1	0	0	0	110.3	L75 L409 V415 L416 I417	L75-I413 HydrophobicContact CD1-CG2 3.94Å; L409-I413 HydrophobicContact CD1-CD1 3.95Å; L409-I413 HydrophobicContact CD1-CG1 4.1Å; L409-I413 HydrophobicContact CD2-CD1 4.36Å; L409-I413 HydrophobicContact CG-CD1 3.73Å; L409-I413 HydrophobicContact CG-CG1 4.3Å; L409-I413 WeakPolarHBondContact O-CB 3.05Å; L409-I413 VanDerWaalsContact O-CG1 3.25Å; L409-I413 WeakPolarHBondContact O-CG1 3.25Å; L409-I413 PolarHBondContact O-N 3.24Å; I413-V415 PolarHBondContact O-N 3.44Å; I413-L416 PolarHBondContact O-N 3.25Å; I413-I417 HydrophobicContact CG2-CD1 3.73Å; I413-I417 HydrophobicContact CG2-CG1 4.46Å; I413-I417 WeakPolarHBondContact O-CG1 3.43Å; I413-I417 PolarHBondContact O-N 3.32Å
414	Y	97.3	Very high	95.6	Very high	0 Å²	0	54.1 Å²	54.1	0%	0	27%	0.274	C	S	.	.	H	α-helix	trans	-62.1	-44.9	-179.7	-166.7	-82.8	0	0	0	112.2	F72 L75 G76 W380 I383 V387 F410 A411 I412 I417 T418	F72-Y414 AromaticContact CD1-CE2 3.74Å; F72-Y414 HydrophobicContact CD1-CE2 3.74Å; F72-Y414 AromaticContact CD2-CD2 3.76Å; F72-Y414 HydrophobicContact CD2-CD2 3.76Å; F72-Y414 AromaticContact CD2-CE2 3.81Å; F72-Y414 HydrophobicContact CD2-CE2 3.81Å; F72-Y414 HydrophobicContact CD2-CG 4.47Å; F72-Y414 HydrophobicContact CE1-CD2 4.31Å; F72-Y414 HydrophobicContact CE1-CE1 4.29Å; F72-Y414 AromaticContact CE1-CE2 3.44Å; F72-Y414 HydrophobicContact CE1-CE2 3.44Å; F72-Y414 VanDerWaalsContact CE1-CE2 3.44Å; F72-Y414 AromaticContact CE1-CZ 3.43Å; F72-Y414 VanDerWaalsContact CE1-CZ 3.43Å; F72-Y414 VanDerWaalsContact CE1-OH 3.27Å; F72-Y414 WeakPolarHBondContact CE1-OH 3.28Å; F72-Y414 HydrophobicContact CE2-CD1 4.17Å; F72-Y414 AromaticContact CE2-CD2 3.46Å; F72-Y414 HydrophobicContact CE2-CD2 3.46Å; F72-Y414 VanDerWaalsContact CE2-CD2 3.46Å; F72-Y414 HydrophobicContact CE2-CE1 4.17Å; F72-Y414 AromaticContact CE2-CE2 3.46Å; F72-Y414 HydrophobicContact CE2-CE2 3.46Å; F72-Y414 VanDerWaalsContact CE2-CE2 3.46Å; F72-Y414 AromaticContact CE2-CG 3.83Å; F72-Y414 HydrophobicContact CE2-CG 3.83Å; F72-Y414 AromaticContact CE2-CZ 3.83Å; F72-Y414 HydrophobicContact CG-CD2 4.29Å; F72-Y414 AromaticContact CG-CE2 3.95Å; F72-Y414 HydrophobicContact CG-CE2 3.95Å; F72-Y414 HydrophobicContact CZ-CD1 4.12Å; F72-Y414 AromaticContact CZ-CD2 3.8Å; F72-Y414 HydrophobicContact CZ-CD2 3.8Å; F72-Y414 AromaticContact CZ-CE1 3.67Å; F72-Y414 HydrophobicContact CZ-CE1 3.67Å; F72-Y414 AromaticContact CZ-CE2 3.3Å; F72-Y414 HydrophobicContact CZ-CE2 3.3Å; F72-Y414 HydrophobicContact CZ-CG 4.19Å; F72-Y414 AromaticContact CZ-CZ 3.23Å; F72-Y414 WeakPolarHBondContact O-CD2 3.4Å; F72-Y414 WeakPolarHBondContact O-CE2 3.22Å; L75-Y414 HydrophobicContact CB-CD2 4.1Å; G76-Y414 VanDerWaalsContact CA-CD2 3.49Å; G76-Y414 VanDerWaalsContact N-CD2 3.33Å; W380-Y414 WeakPolarHBondContact CZ3-OH 3.39Å; I383-Y414 HydrophobicContact CG2-CE1 4Å; I383-Y414 VanDerWaalsContact CG2-OH 3.22Å; I383-Y414 WeakPolarHBondContact CG2-OH 3.37Å; V387-Y414 HydrophobicContact CB-CD1 3.73Å; V387-Y414 HydrophobicContact CB-CE1 4.16Å; V387-Y414 HydrophobicContact CB-CG 4.46Å; V387-Y414 HydrophobicContact CG1-CD1 3.77Å; V387-Y414 HydrophobicContact CG1-CG 4.05Å; V387-Y414 HydrophobicContact CG2-CD1 3.63Å; V387-Y414 HydrophobicContact CG2-CE1 3.66Å; V387-Y414 HydrophobicContact CG2-CG 4.28Å; F410-Y414 VanDerWaalsContact O-CB 3.29Å; F410-Y414 WeakPolarHBondContact O-CB 3.37Å; F410-Y414 PolarHBondContact O-N 2.84Å; A411-Y414 PolarHBondContact O-N 3.48Å; I412-Y414 VanDerWaalsContact C-N 3.3Å; I412-Y414 PolarHBondContact O-N 3.15Å; Y414-I417 PolarHBondContact O-N 3.33Å; Y414-T418 WeakPolarHBondContact CE1-OG1 3.44Å; Y414-T418 WeakPolarHBondContact O-CB 3.37Å; Y414-T418 PolarHBondContact O-N 3Å; Y414-T418 PolarHBondContact O-OG1 3.42Å
415	V	97.2	Very high	95.6	Very high	29 Å²	29	53.8 Å²	53.8	18%	0.176	27%	0.272	C	S	.	.	H	α-helix	trans	-65.1	-41.4	177.8	170.6	0	0	0	0	111	V387 I391 A411 I412 I413 T418 L419	V387-V415 HydrophobicContact CG1-CG2 4.32Å; I391-V415 HydrophobicContact CD1-CG2 4.1Å; A411-V415 WeakPolarHBondContact O-CB 3.41Å; A411-V415 VanDerWaalsContact O-CG2 3.27Å; A411-V415 WeakPolarHBondContact O-CG2 3.32Å; A411-V415 PolarHBondContact O-N 3.43Å; I412-V415 PolarHBondContact O-N 2.98Å; I413-V415 PolarHBondContact O-N 3.44Å; V415-T418 PolarHBondContact O-N 3.01Å; V415-L419 HydrophobicContact CG1-CD1 4.04Å; V415-L419 HydrophobicContact CG1-CG 4.4Å; V415-L419 WeakPolarHBondContact O-CB 3.47Å; V415-L419 VanDerWaalsContact O-CG 3.31Å; V415-L419 WeakPolarHBondContact O-CG 3.3Å; V415-L419 PolarHBondContact O-N 2.87Å
416	L	97.4	Very high	95.5	Very high	108 Å²	108	50.8 Å²	50.8	57%	0.565	26%	0.259	S	S	*	.	H	α-helix	trans	-62	-46	176.8	-72.9	176	0	0	0	112.2	I412 I413 T418 L419 F420	I412-L416 HydrophobicContact CG2-CD1 3.95Å; I412-L416 HydrophobicContact CG2-CG 4.37Å; I412-L416 WeakPolarHBondContact O-CB 3.26Å; I412-L416 VanDerWaalsContact O-CG 3.31Å; I412-L416 WeakPolarHBondContact O-CG 3.37Å; I412-L416 PolarHBondContact O-N 3.34Å; I413-L416 PolarHBondContact O-N 3.25Å; L416-T418 VanDerWaalsContact C-N 3.32Å; L416-L419 PolarHBondContact O-N 3.41Å; L416-F420 PolarHBondContact O-N 3.4Å
417	I	96.8	Very high	95.4	Very high	56 Å²	56	55.8 Å²	55.8	29%	0.287	29%	0.289	S	S	.	.	H	α-helix	trans	-65.1	-39.9	176.2	-66.3	169.2	0	0	0	110.3	F72 I413 Y414 L419 F420 L421	F72-I417 HydrophobicContact CD2-CB 3.99Å; F72-I417 HydrophobicContact CD2-CD1 4.01Å; F72-I417 HydrophobicContact CD2-CG2 3.61Å; F72-I417 HydrophobicContact CE2-CB 3.68Å; F72-I417 HydrophobicContact CE2-CG2 3.46Å; F72-I417 VanDerWaalsContact CE2-CG2 3.46Å; F72-I417 HydrophobicContact CZ-CG2 4.26Å; I413-I417 HydrophobicContact CG2-CD1 3.73Å; I413-I417 HydrophobicContact CG2-CG1 4.46Å; I413-I417 WeakPolarHBondContact O-CG1 3.43Å; I413-I417 PolarHBondContact O-N 3.32Å; Y414-I417 PolarHBondContact O-N 3.33Å; I417-L419 VanDerWaalsContact C-N 3.35Å; I417-L419 PolarHBondContact O-N 3.18Å; I417-F420 WeakPolarHBondContact O-CB 3.43Å; I417-F420 PolarHBondContact O-N 3.47Å; I417-L421 HydrophobicContact CG2-CD1 4.24Å; I417-L421 HydrophobicContact CG2-CG 4.38Å; I417-L421 WeakPolarHBondContact O-CG 3.28Å; I417-L421 PolarHBondContact O-N 3.18Å
418	T	96.6	Very high	95.1	Very high	6 Å²	6	54.3 Å²	54.3	4%	0.037	28%	0.282	C	S	.	.	H	α-helix	trans	-62.7	-42.6	176.9	-54.9	0	0	0	0	111.7	W380 Y414 V415 L416 F420 L421 V422	W380-T418 VanDerWaalsContact O-CG2 3.29Å; W380-T418 WeakPolarHBondContact O-CG2 3.31Å; Y414-T418 WeakPolarHBondContact CE1-OG1 3.44Å; Y414-T418 WeakPolarHBondContact O-CB 3.37Å; Y414-T418 PolarHBondContact O-N 3Å; Y414-T418 PolarHBondContact O-OG1 3.42Å; V415-T418 PolarHBondContact O-N 3.01Å; L416-T418 VanDerWaalsContact C-N 3.32Å; T418-F420 VanDerWaalsContact C-N 3.35Å; T418-L421 PolarHBondContact O-N 3.25Å; T418-V422 HydrophobicContact CG2-CG2 4.35Å; T418-V422 VanDerWaalsContact O-CG2 3.29Å; T418-V422 WeakPolarHBondContact O-CG2 3.49Å; T418-V422 PolarHBondContact O-N 3.37Å
419	L	95.5	Very high	94.8	Very high	92 Å²	92	51 Å²	51	48%	0.482	27%	0.266	S	S	.	.	H	α-helix	trans	-61.9	-43.1	174.8	-73.5	169.8	0	0	0	111.4	V415 L416 I417 L421 V422 I423	V415-L419 HydrophobicContact CG1-CD1 4.04Å; V415-L419 HydrophobicContact CG1-CG 4.4Å; V415-L419 WeakPolarHBondContact O-CB 3.47Å; V415-L419 VanDerWaalsContact O-CG 3.31Å; V415-L419 WeakPolarHBondContact O-CG 3.3Å; V415-L419 PolarHBondContact O-N 2.87Å; L416-L419 PolarHBondContact O-N 3.41Å; I417-L419 VanDerWaalsContact C-N 3.35Å; I417-L419 PolarHBondContact O-N 3.18Å; L419-L421 PolarHBondContact O-N 3.01Å; L419-V422 PolarHBondContact O-N 3.12Å; L419-I423 WeakPolarHBondContact O-CB 3.43Å; L419-I423 WeakPolarHBondContact O-CD1 3.47Å; L419-I423 WeakPolarHBondContact O-CG1 3.37Å; L419-I423 PolarHBondContact O-N 3.37Å
420	F	96.4	Very high	94.5	Very high	75 Å²	75	49 Å²	49	33%	0.329	26%	0.259	S	S	.	.	H	α-helix	trans	-55.8	-51.4	173.6	174.2	-85.7	0	0	0	111.2	P215 L416 I417 T418 V422 I423 F424	P215-F420 HydrophobicContact CB-CE2 4.29Å; P215-F420 HydrophobicContact CB-CZ 3.89Å; L416-F420 PolarHBondContact O-N 3.4Å; I417-F420 WeakPolarHBondContact O-CB 3.43Å; I417-F420 PolarHBondContact O-N 3.47Å; T418-F420 VanDerWaalsContact C-N 3.35Å; F420-V422 PolarHBondContact O-N 3.2Å; F420-I423 PolarHBondContact O-N 3.26Å; F420-F424 HydrophobicContact CD1-CD2 4.21Å; F420-F424 AromaticContact CD2-CD2 3.51Å; F420-F424 HydrophobicContact CD2-CD2 3.51Å; F420-F424 AromaticContact CD2-CE2 3.46Å; F420-F424 HydrophobicContact CD2-CE2 3.46Å; F420-F424 VanDerWaalsContact CD2-CE2 3.46Å; F420-F424 HydrophobicContact CE1-CD2 4.07Å; F420-F424 AromaticContact CE2-CD2 3.36Å; F420-F424 HydrophobicContact CE2-CD2 3.36Å; F420-F424 AromaticContact CE2-CE2 3.23Å; F420-F424 HydrophobicContact CE2-CE2 3.23Å; F420-F424 HydrophobicContact CE2-CG 4.47Å; F420-F424 HydrophobicContact CE2-CZ 4.25Å; F420-F424 AromaticContact CG-CD2 3.94Å; F420-F424 HydrophobicContact CG-CD2 3.94Å; F420-F424 HydrophobicContact CG-CE2 4.32Å; F420-F424 AromaticContact CZ-CD2 3.66Å; F420-F424 HydrophobicContact CZ-CD2 3.66Å; F420-F424 AromaticContact CZ-CE2 3.95Å; F420-F424 HydrophobicContact CZ-CE2 3.95Å; F420-F424 HydrophobicContact CZ-CG 4.43Å; F420-F424 WeakPolarHBondContact O-CD2 3.4Å; F420-F424 PolarHBondContact O-N 3.26Å
421	L	95.4	Very high	94.3	Very high	2 Å²	2	50.1 Å²	50.1	1%	0.01	27%	0.271	C	S	.	.	H	α-helix	trans	-60.5	-44.8	179.9	-66.6	175.4	0	0	0	111.6	T219 F222 Y223 L226 I417 T418 L419 A425	T219-L421 HydrophobicContact CG2-CB 4.4Å; T219-L421 HydrophobicContact CG2-CD2 4.07Å; T219-L421 VanDerWaalsContact CG2-O 3.25Å; T219-L421 WeakPolarHBondContact CG2-O 3.15Å; F222-L421 HydrophobicContact CB-CD1 4.5Å; F222-L421 HydrophobicContact CB-CD2 3.61Å; F222-L421 HydrophobicContact CD1-CD1 4.11Å; F222-L421 HydrophobicContact CD1-CD2 4.27Å; F222-L421 HydrophobicContact CG-CD2 3.95Å; Y223-L421 HydrophobicContact CE1-CB 3.94Å; Y223-L421 HydrophobicContact CE1-CD1 4.25Å; Y223-L421 PolarHBondContact OH-O 3.22Å; L226-L421 HydrophobicContact CD1-CD1 4.12Å; I417-L421 HydrophobicContact CG2-CD1 4.24Å; I417-L421 HydrophobicContact CG2-CG 4.38Å; I417-L421 WeakPolarHBondContact O-CG 3.28Å; I417-L421 PolarHBondContact O-N 3.18Å; T418-L421 PolarHBondContact O-N 3.25Å; L419-L421 PolarHBondContact O-N 3.01Å; L421-A425 WeakPolarHBondContact O-CB 3.38Å; L421-A425 PolarHBondContact O-N 3.49Å
422	V	93.2	Very high	93.9	Very high	21 Å²	21	52.4 Å²	52.4	13%	0.127	28%	0.282	C	S	.	.	H	α-helix	trans	-64.2	-44	179.5	169.3	0	0	0	0	111.5	F377 L381 T418 L419 F420 A425 F426	F377-V422 HydrophobicContact CE2-CG1 3.91Å; F377-V422 HydrophobicContact CZ-CG1 4.41Å; L381-V422 HydrophobicContact CB-CG2 4.23Å; L381-V422 HydrophobicContact CD1-CG1 4.48Å; L381-V422 HydrophobicContact CD1-CG2 3.99Å; T418-V422 HydrophobicContact CG2-CG2 4.35Å; T418-V422 VanDerWaalsContact O-CG2 3.29Å; T418-V422 WeakPolarHBondContact O-CG2 3.49Å; T418-V422 PolarHBondContact O-N 3.37Å; L419-V422 PolarHBondContact O-N 3.12Å; F420-V422 PolarHBondContact O-N 3.2Å; V422-A425 PolarHBondContact O-N 3.34Å; V422-F426 HydrophobicContact CG1-CE2 4.22Å; V422-F426 WeakPolarHBondContact O-CD2 3.2Å
423	I	94.4	Very high	93.6	Very high	102 Å²	102	49.1 Å²	49.1	52%	0.523	27%	0.265	S	S	.	.	H	α-helix	trans	-64.4	-49.5	-179.6	-70	165.5	0	0	0	110.4	L419 F420 A425 F426	L419-I423 WeakPolarHBondContact O-CB 3.43Å; L419-I423 WeakPolarHBondContact O-CD1 3.47Å; L419-I423 WeakPolarHBondContact O-CG1 3.37Å; L419-I423 PolarHBondContact O-N 3.37Å; F420-I423 PolarHBondContact O-N 3.26Å; I423-A425 VanDerWaalsContact C-N 3.29Å; I423-A425 PolarHBondContact O-N 2.94Å; I423-F426 PolarHBondContact O-N 3.37Å
424	F	94.8	Very high	93.3	Very high	58 Å²	58	51.3 Å²	51.3	25%	0.254	28%	0.277	S	S	.	.	H	α-helix	trans	-77.2	-15.5	-177.3	-75.5	-70	0	0	0	113.3	P215 T219 F420 F426 V427 A428	P215-F424 HydrophobicContact CB-CB 4.42Å; P215-F424 HydrophobicContact CB-CD1 3.34Å; P215-F424 HydrophobicContact CB-CD2 3.88Å; P215-F424 HydrophobicContact CB-CE1 3.35Å; P215-F424 HydrophobicContact CB-CE2 3.9Å; P215-F424 HydrophobicContact CB-CG 3.61Å; P215-F424 HydrophobicContact CB-CZ 3.63Å; P215-F424 HydrophobicContact CG-CD1 4.36Å; P215-F424 HydrophobicContact CG-CE1 3.9Å; P215-F424 HydrophobicContact CG-CZ 4.01Å; T219-F424 HydrophobicContact CG2-CB 4.49Å; T219-F424 VanDerWaalsContact OG1-CB 3.25Å; T219-F424 WeakPolarHBondContact OG1-CB 3.37Å; F420-F424 HydrophobicContact CD1-CD2 4.21Å; F420-F424 AromaticContact CD2-CD2 3.51Å; F420-F424 HydrophobicContact CD2-CD2 3.51Å; F420-F424 AromaticContact CD2-CE2 3.46Å; F420-F424 HydrophobicContact CD2-CE2 3.46Å; F420-F424 VanDerWaalsContact CD2-CE2 3.46Å; F420-F424 HydrophobicContact CE1-CD2 4.07Å; F420-F424 AromaticContact CE2-CD2 3.36Å; F420-F424 HydrophobicContact CE2-CD2 3.36Å; F420-F424 AromaticContact CE2-CE2 3.23Å; F420-F424 HydrophobicContact CE2-CE2 3.23Å; F420-F424 HydrophobicContact CE2-CG 4.47Å; F420-F424 HydrophobicContact CE2-CZ 4.25Å; F420-F424 AromaticContact CG-CD2 3.94Å; F420-F424 HydrophobicContact CG-CD2 3.94Å; F420-F424 HydrophobicContact CG-CE2 4.32Å; F420-F424 AromaticContact CZ-CD2 3.66Å; F420-F424 HydrophobicContact CZ-CD2 3.66Å; F420-F424 AromaticContact CZ-CE2 3.95Å; F420-F424 HydrophobicContact CZ-CE2 3.95Å; F420-F424 HydrophobicContact CZ-CG 4.43Å; F420-F424 WeakPolarHBondContact O-CD2 3.4Å; F420-F424 PolarHBondContact O-N 3.26Å; F424-F426 VanDerWaalsContact C-N 3.34Å; F424-V427 HydrophobicContact CD1-CG2 4.39Å; F424-V427 PolarHBondContact O-N 2.93Å; F424-A428 VanDerWaalsContact O-CB 3.27Å; F424-A428 WeakPolarHBondContact O-CB 3.5Å; F424-A428 PolarHBondContact O-N 3.24Å
425	A	91.4	Very high	92.9	Very high	1 Å²	1	55.4 Å²	55.4	1%	0.008	30%	0.298	C	S	.	.	H	α-helix	trans	-63.2	-40.4	169	0	0	0	0	0	111.6	T219 Y223 F377 L421 V422 I423 V427 A428 A429 S433	T219-A425 HydrophobicContact CG2-CB 4.11Å; Y223-A425 HydrophobicContact CE2-CB 3.72Å; F377-A425 HydrophobicContact CD2-CB 3.89Å; F377-A425 HydrophobicContact CE2-CB 4.48Å; L421-A425 WeakPolarHBondContact O-CB 3.38Å; L421-A425 PolarHBondContact O-N 3.49Å; V422-A425 PolarHBondContact O-N 3.34Å; I423-A425 VanDerWaalsContact C-N 3.29Å; I423-A425 PolarHBondContact O-N 2.94Å; A425-V427 PolarHBondContact O-N 3.48Å; A425-A428 PolarHBondContact O-N 3.46Å; A425-A429 CarbonylContact O-C 3.58Å; A425-A429 VanDerWaalsContact O-C 3.27Å; A425-A429 WeakPolarHBondContact O-CA 3.49Å; A425-A429 PolarHBondContact O-N 2.87Å; A425-S433 VanDerWaalsContact C-OG 3.24Å; A425-S433 PolarHBondContact O-OG 3.23Å; A425-S433 VanDerWaalsContact O-OG 3.11Å
426	F	91.9	Very high	92.5	Very high	79 Å²	79	54 Å²	54	35%	0.346	29%	0.29	S	S	.	.	H	α-helix	trans	-65.4	-26.8	175.2	-75	-75.6	0	0	0	113.3	F377 V422 I423 F424 P430 L434 V437	F377-F426 HydrophobicContact CE2-CD2 4.32Å; F377-F426 AromaticContact CE2-CE2 3.61Å; F377-F426 HydrophobicContact CE2-CE2 3.61Å; F377-F426 AromaticContact CE2-CZ 3.84Å; F377-F426 HydrophobicContact CE2-CZ 3.84Å; F377-F426 AromaticContact CZ-CE2 3.81Å; F377-F426 HydrophobicContact CZ-CE2 3.81Å; F377-F426 AromaticContact CZ-CZ 3.65Å; F377-F426 HydrophobicContact CZ-CZ 3.65Å; V422-F426 HydrophobicContact CG1-CE2 4.22Å; V422-F426 WeakPolarHBondContact O-CD2 3.2Å; I423-F426 PolarHBondContact O-N 3.37Å; F424-F426 VanDerWaalsContact C-N 3.34Å; F426-P430 WeakPolarHBondContact O-CB 3.28Å; F426-L434 HydrophobicContact CE1-CD2 4.18Å; F426-L434 HydrophobicContact CE1-CG 4.43Å; F426-V437 HydrophobicContact CE1-CG2 4.32Å; F426-V437 HydrophobicContact CZ-CG2 3.81Å
427	V	90.6	Very high	92.2	Very high	106 Å²	106	51.4 Å²	51.4	64%	0.642	28%	0.278	S	S	*	.	H	α-helix	trans	-80.5	-42.4	175.7	-178.9	0	0	0	0	110.7	F424 A425	F424-V427 HydrophobicContact CD1-CG2 4.39Å; F424-V427 PolarHBondContact O-N 2.93Å; A425-V427 PolarHBondContact O-N 3.48Å
428	A	88.9	Confident	92	Very high	30 Å²	30	51.1 Å²	51.1	25%	0.248	28%	0.284	C	S	.	.	H	α-helix	trans	-84.3	-32.8	-171.9	0	0	0	0	0	114.4	G216 K220 F424 A425	G216-A428 WeakPolarHBondContact O-CB 3.44Å; K220-A428 HydrophobicContact CD-CB 4.25Å; K220-A428 HydrophobicContact CG-CB 4.03Å; F424-A428 VanDerWaalsContact O-CB 3.27Å; F424-A428 WeakPolarHBondContact O-CB 3.5Å; F424-A428 PolarHBondContact O-N 3.24Å; A425-A428 PolarHBondContact O-N 3.46Å
429	A	87.8	Confident	91.6	Very high	6 Å²	6	52.9 Å²	52.9	5%	0.05	29%	0.293	C	S	.	.			trans	-147.8	64.8	-172.4	0	0	0	0	0	109.7	T373 A425 V431 E432 S433	T373-A429 HydrophobicContact CG2-CB 3.62Å; A425-A429 CarbonylContact O-C 3.58Å; A425-A429 VanDerWaalsContact O-C 3.27Å; A425-A429 WeakPolarHBondContact O-CA 3.49Å; A425-A429 PolarHBondContact O-N 2.87Å; A429-V431 VanDerWaalsContact C-N 3.33Å; A429-V431 PolarHBondContact O-N 3.34Å; A429-E432 VanDerWaalsContact C-OE2 3.28Å; A429-E432 WeakPolarHBondContact CA-OE2 3.33Å; A429-E432 HydrophobicContact CB-CB 4.28Å; A429-E432 WeakPolarHBondContact CB-OE2 3.18Å; A429-S433 VanDerWaalsContact O-CB 3.3Å; A429-S433 WeakPolarHBondContact O-CB 3.36Å; A429-S433 PolarHBondContact O-N 3.42Å; A429-S433 PolarHBondContact O-OG 2.84Å
430	P	91.9	Very high	91.3	Very high	61 Å²	61	50 Å²	50	40%	0.396	28%	0.278	S	S	.	.	H	α-helix	trans	-62.3	-38.7	-172.4	21.6	-31.9	0	0	0	112.6	F426 L434	F426-P430 WeakPolarHBondContact O-CB 3.28Å; P430-L434 VanDerWaalsContact O-CB 3.25Å; P430-L434 WeakPolarHBondContact O-CB 3.5Å; P430-L434 WeakPolarHBondContact O-CD1 3.46Å; P430-L434 WeakPolarHBondContact O-CG 3.24Å; P430-L434 PolarHBondContact O-N 3.45Å
431	V	90.9	Very high	91.2	Very high	91 Å²	91	49.2 Å²	49.2	55%	0.552	28%	0.281	S	S	*	.	H	α-helix	trans	-66.8	-49.2	-176.8	178.5	0	0	0	0	110	A429 S433 L434 L435	A429-V431 VanDerWaalsContact C-N 3.33Å; A429-V431 PolarHBondContact O-N 3.34Å; V431-S433 VanDerWaalsContact C-N 3.35Å; V431-S433 PolarHBondContact O-N 2.87Å; V431-L434 PolarHBondContact O-N 2.82Å; V431-L435 HydrophobicContact CG1-CD1 4.08Å; V431-L435 WeakPolarHBondContact O-CB 2.99Å; V431-L435 VanDerWaalsContact O-CG 3.26Å; V431-L435 WeakPolarHBondContact O-CG 3.39Å; V431-L435 PolarHBondContact O-N 3.26Å
432	E	89.3	Confident	91.1	Very high	48 Å²	48	52.1 Å²	52.1	22%	0.224	30%	0.299	C	S	.	.	H	α-helix	trans	-63.3	-42.5	179.6	-60.8	73.8	-165	0	0	110.7	T373 A429 L435 G436	T373-E432 HydrophobicContact CG2-CB 4.29Å; A429-E432 VanDerWaalsContact C-OE2 3.28Å; A429-E432 WeakPolarHBondContact CA-OE2 3.33Å; A429-E432 HydrophobicContact CB-CB 4.28Å; A429-E432 WeakPolarHBondContact CB-OE2 3.18Å; E432-L435 PolarHBondContact O-N 3.45Å; E432-G436 PolarHBondContact O-N 3.23Å
433	S	90.1	Very high	91.1	Very high	0 Å²	0	51.1 Å²	51.1	0%	0	29%	0.293	C	S	.	.	H	α-helix	trans	-65.9	-43.4	177.9	-56.9	0	0	0	0	111.9	A425 A429 V431 G436 V437	A425-S433 VanDerWaalsContact C-OG 3.24Å; A425-S433 PolarHBondContact O-OG 3.23Å; A425-S433 VanDerWaalsContact O-OG 3.11Å; A429-S433 VanDerWaalsContact O-CB 3.3Å; A429-S433 WeakPolarHBondContact O-CB 3.36Å; A429-S433 PolarHBondContact O-N 3.42Å; A429-S433 PolarHBondContact O-OG 2.84Å; V431-S433 VanDerWaalsContact C-N 3.35Å; V431-S433 PolarHBondContact O-N 2.87Å; S433-G436 WeakPolarHBondContact O-CA 3.4Å; S433-G436 PolarHBondContact O-N 3.43Å; S433-V437 PolarHBondContact O-N 3.45Å
434	L	91.6	Very high	91.1	Very high	106 Å²	106	49.1 Å²	49.1	56%	0.555	28%	0.282	S	S	*	.	H	α-helix	trans	-65.6	-40.1	176.7	-74.9	169.9	0	0	0	112	F426 P430 V431 G436 V437 A438	F426-L434 HydrophobicContact CE1-CD2 4.18Å; F426-L434 HydrophobicContact CE1-CG 4.43Å; P430-L434 VanDerWaalsContact O-CB 3.25Å; P430-L434 WeakPolarHBondContact O-CB 3.5Å; P430-L434 WeakPolarHBondContact O-CD1 3.46Å; P430-L434 WeakPolarHBondContact O-CG 3.24Å; P430-L434 PolarHBondContact O-N 3.45Å; V431-L434 PolarHBondContact O-N 2.82Å; L434-G436 VanDerWaalsContact C-N 3.28Å; L434-G436 PolarHBondContact O-N 3.47Å; L434-V437 PolarHBondContact O-N 2.9Å; L434-A438 WeakPolarHBondContact O-CB 3.03Å; L434-A438 PolarHBondContact O-N 2.85Å
435	L	88.8	Confident	91.1	Very high	87 Å²	87	49.5 Å²	49.5	46%	0.455	29%	0.291	S	S	.	.	H	α-helix	trans	-60.9	-40.5	172.2	-73.4	171.4	0	0	0	111	Y374 V431 E432 A438 I439	Y374-L435 HydrophobicContact CD2-CB 4.23Å; Y374-L435 HydrophobicContact CE2-CB 4.29Å; V431-L435 HydrophobicContact CG1-CD1 4.08Å; V431-L435 WeakPolarHBondContact O-CB 2.99Å; V431-L435 VanDerWaalsContact O-CG 3.26Å; V431-L435 WeakPolarHBondContact O-CG 3.39Å; V431-L435 PolarHBondContact O-N 3.26Å; E432-L435 PolarHBondContact O-N 3.45Å; L435-A438 PolarHBondContact O-N 3.34Å; L435-I439 WeakPolarHBondContact O-CG1 3.13Å; L435-I439 PolarHBondContact O-N 3.24Å
436	G	88.5	Confident	91.2	Very high	0 Å²	0	52.3 Å²	52.3	0%	0	31%	0.307	C	S	.	.	H	α-helix	trans	-54.3	-52.9	172.6	0	0	0	0	0	112.5	Y374 E432 S433 L434 I440	Y374-G436 VanDerWaalsContact CE2-CA 3.44Å; E432-G436 PolarHBondContact O-N 3.23Å; S433-G436 WeakPolarHBondContact O-CA 3.4Å; S433-G436 PolarHBondContact O-N 3.43Å; L434-G436 VanDerWaalsContact C-N 3.28Å; L434-G436 PolarHBondContact O-N 3.47Å; G436-I440 VanDerWaalsContact O-CG1 3.31Å; G436-I440 WeakPolarHBondContact O-CG1 3.42Å; G436-I440 PolarHBondContact O-N 3.03Å; G436-I440 VanDerWaalsContact O-N 3.14Å
437	V	91.4	Very high	91.2	Very high	53 Å²	53	50.4 Å²	50.4	32%	0.321	30%	0.298	S	S	.	.	H	α-helix	trans	-61.8	-46.7	176.7	176.4	0	0	0	0	111.1	F377 F426 S433 L434 I439 I440 C441	F377-V437 HydrophobicContact CE1-CG2 3.73Å; F377-V437 HydrophobicContact CZ-CG2 3.75Å; F426-V437 HydrophobicContact CE1-CG2 4.32Å; F426-V437 HydrophobicContact CZ-CG2 3.81Å; S433-V437 PolarHBondContact O-N 3.45Å; L434-V437 PolarHBondContact O-N 2.9Å; V437-I439 VanDerWaalsContact C-N 3.32Å; V437-I439 PolarHBondContact O-N 3.34Å; V437-I440 PolarHBondContact O-N 3.34Å; V437-C441 WeakPolarHBondContact O-CB 3.44Å; V437-C441 PolarHBondContact O-N 2.9Å; V437-C441 PolarHBondContact O-SG 3Å
438	A	92.1	Very high	91.3	Very high	49 Å²	49	49.8 Å²	49.8	41%	0.405	29%	0.291	S	S	.	.	H	α-helix	trans	-57.8	-44.4	-177.4	0	0	0	0	0	111.8	L434 L435 C441 T442	L434-A438 WeakPolarHBondContact O-CB 3.03Å; L434-A438 PolarHBondContact O-N 2.85Å; L435-A438 PolarHBondContact O-N 3.34Å; A438-C441 CarbonylContact O-C 3.27Å; A438-C441 WeakPolarHBondContact O-CA 3.42Å; A438-C441 WeakPolarHBondContact O-CB 3.37Å; A438-C441 PolarHBondContact O-N 3.03Å; A438-T442 WeakPolarHBondContact O-CG2 3.47Å; A438-T442 PolarHBondContact O-N 3.33Å
439	I	88	Confident	91.3	Very high	44 Å²	44	52.6 Å²	52.6	23%	0.226	30%	0.301	C	S	.	.	H	α-helix	trans	-74.9	-31.7	-178.2	-64	169	0	0	0	112	W111 V116 Y374 L435 V437 C441 T442	W111-I439 PolarHBondContact NE1-O 3.46Å; W111-I439 VanDerWaalsContact NE1-O 3.14Å; V116-I439 HydrophobicContact CG2-CB 4.23Å; V116-I439 HydrophobicContact CG2-CG2 3.31Å; Y374-I439 HydrophobicContact CE2-CD1 3.93Å; Y374-I439 WeakPolarHBondContact OH-CD1 3.31Å; L435-I439 WeakPolarHBondContact O-CG1 3.13Å; L435-I439 PolarHBondContact O-N 3.24Å; V437-I439 VanDerWaalsContact C-N 3.32Å; V437-I439 PolarHBondContact O-N 3.34Å; I439-C441 VanDerWaalsContact C-N 3.31Å; I439-T442 PolarHBondContact O-N 2.8Å; I439-T442 PolarHBondContact O-OG1 3.27Å
440	I	91	Very high	91.3	Very high	32 Å²	32	54 Å²	54	16%	0.164	32%	0.316	C	S	.	.	H	α-helix	trans	-62.5	-44.4	167.4	-65.2	168.5	0	0	0	109.5	V378 L381 G436 V437 T442 G443	V378-I440 HydrophobicContact CB-CD1 4.49Å; V378-I440 HydrophobicContact CG1-CD1 4.06Å; V378-I440 HydrophobicContact CG1-CG1 4.17Å; V378-I440 HydrophobicContact CG2-CD1 4.15Å; V378-I440 HydrophobicContact CG2-CG1 4.43Å; L381-I440 HydrophobicContact CD2-CD1 4.18Å; G436-I440 VanDerWaalsContact O-CG1 3.31Å; G436-I440 WeakPolarHBondContact O-CG1 3.42Å; G436-I440 PolarHBondContact O-N 3.03Å; G436-I440 VanDerWaalsContact O-N 3.14Å; V437-I440 PolarHBondContact O-N 3.34Å; I440-T442 VanDerWaalsContact C-N 3.27Å; I440-T442 PolarHBondContact O-N 3.18Å; I440-G443 PolarHBondContact O-N 3.2Å
441	C	93.2	Very high	91	Very high	58 Å²	58	52.9 Å²	52.9	39%	0.392	31%	0.309	S	S	.	.	H	α-helix	trans	-64.6	-26	178.9	-72.2	0	0	0	0	113.3	V437 A438 I439 G443 I444 P445	V437-C441 WeakPolarHBondContact O-CB 3.44Å; V437-C441 PolarHBondContact O-N 2.9Å; V437-C441 PolarHBondContact O-SG 3Å; A438-C441 CarbonylContact O-C 3.27Å; A438-C441 WeakPolarHBondContact O-CA 3.42Å; A438-C441 WeakPolarHBondContact O-CB 3.37Å; A438-C441 PolarHBondContact O-N 3.03Å; I439-C441 VanDerWaalsContact C-N 3.31Å; C441-G443 PolarHBondContact O-N 3.34Å; C441-I444 HydrophobicContact CB-CD1 4.38Å; C441-I444 VanDerWaalsContact O-CB 3.3Å; C441-I444 WeakPolarHBondContact O-CB 3.28Å; C441-I444 WeakPolarHBondContact O-CG1 3.33Å; C441-I444 PolarHBondContact O-N 3.44Å; C441-P445 WeakPolarHBondContact O-CD 3.35Å
442	T	94.1	Very high	90.8	Very high	62 Å²	62	51 Å²	51	38%	0.38	30%	0.303	S	S	.	.	T	Hydrogen-bonded Turn	trans	-64.6	-17.8	171.9	69	0	0	0	0	112.6	W111 A438 I439 I440 I444 P445 V446	W111-T442 PolarHBondContact NE1-OG1 3.47Å; A438-T442 WeakPolarHBondContact O-CG2 3.47Å; A438-T442 PolarHBondContact O-N 3.33Å; I439-T442 PolarHBondContact O-N 2.8Å; I439-T442 PolarHBondContact O-OG1 3.27Å; I440-T442 VanDerWaalsContact C-N 3.27Å; I440-T442 PolarHBondContact O-N 3.18Å; T442-I444 PolarHBondContact O-N 3.3Å; T442-P445 VanDerWaalsContact O-CD 3.27Å; T442-P445 WeakPolarHBondContact O-CD 3.28Å; T442-P445 VanDerWaalsContact O-CG 3.31Å; T442-P445 WeakPolarHBondContact O-CG 3.34Å; T442-V446 WeakPolarHBondContact O-CG2 3.5Å
443	G	92.8	Very high	90.6	Very high	0 Å²	0	54 Å²	54	0%	0	31%	0.312	C	S	.	.	H	α-helix	trans	-65.8	-26.6	170.5	0	0	0	0	0	113	F107 W111 I440 C441 V446 Y447	F107-G443 WeakPolarHBondContact CE1-O 3.38Å; W111-G443 VanDerWaalsContact CD1-CA 3.43Å; I440-G443 PolarHBondContact O-N 3.2Å; C441-G443 PolarHBondContact O-N 3.34Å; G443-V446 PolarHBondContact O-N 2.94Å; G443-Y447 WeakPolarHBondContact O-CB 3.47Å; G443-Y447 PolarHBondContact O-N 2.9Å
444	I	94.8	Very high	90.3	Very high	61 Å²	61	62.7 Å²	62.7	31%	0.313	35%	0.35	S	S	.	.	H	α-helix	trans	-63.9	-55.9	-179.1	-56.8	175.1	0	0	0	112.1	F104 L108 C441 T442 V446 Y447 I448	F104-I444 HydrophobicContact CE2-CG1 4.27Å; F104-I444 HydrophobicContact CE2-CG2 4.3Å; F104-I444 HydrophobicContact CZ-CD1 4.47Å; F104-I444 HydrophobicContact CZ-CG1 4.02Å; F104-I444 HydrophobicContact CZ-CG2 4.46Å; L108-I444 HydrophobicContact CD2-CG1 3.99Å; C441-I444 HydrophobicContact CB-CD1 4.38Å; C441-I444 VanDerWaalsContact O-CB 3.3Å; C441-I444 WeakPolarHBondContact O-CB 3.28Å; C441-I444 WeakPolarHBondContact O-CG1 3.33Å; C441-I444 PolarHBondContact O-N 3.44Å; T442-I444 PolarHBondContact O-N 3.3Å; I444-V446 VanDerWaalsContact C-N 3.27Å; I444-V446 PolarHBondContact O-N 3.33Å; I444-Y447 WeakPolarHBondContact O-CB 3.23Å; I444-Y447 PolarHBondContact O-N 2.66Å; I444-I448 HydrophobicContact CG2-CD1 3.97Å; I444-I448 WeakPolarHBondContact O-CG1 3.46Å; I444-I448 PolarHBondContact O-N 3.2Å
445	P	94.5	Very high	90	Very high	66 Å²	66	64.5 Å²	64.5	43%	0.429	36%	0.36	S	S	.	.	H	α-helix	trans	-62.6	-36.2	177.9	23.8	-33.4	0	0	0	111.8	C441 T442 I448 I449	C441-P445 WeakPolarHBondContact O-CD 3.35Å; T442-P445 VanDerWaalsContact O-CD 3.27Å; T442-P445 WeakPolarHBondContact O-CD 3.28Å; T442-P445 VanDerWaalsContact O-CG 3.31Å; T442-P445 WeakPolarHBondContact O-CG 3.34Å; P445-I448 PolarHBondContact O-N 3.36Å; P445-I449 WeakPolarHBondContact O-CB 3.34Å; P445-I449 VanDerWaalsContact O-CG1 3.29Å; P445-I449 WeakPolarHBondContact O-CG1 3.4Å; P445-I449 PolarHBondContact O-N 3.04Å
446	V	92.7	Very high	89.8	Confident	59 Å²	59	62.8 Å²	62.8	36%	0.358	35%	0.349	S	S	.	.	H	α-helix	trans	-65.3	-39.5	176.8	-178.9	0	0	0	0	111.3	F107 W111 T442 G443 I444 G450	F107-V446 HydrophobicContact CE1-CB 4.48Å; F107-V446 HydrophobicContact CZ-CB 4.31Å; F107-V446 HydrophobicContact CZ-CG1 3.87Å; W111-V446 HydrophobicContact CE3-CG1 4.34Å; W111-V446 HydrophobicContact CH2-CB 4.3Å; W111-V446 HydrophobicContact CH2-CG1 4.2Å; W111-V446 HydrophobicContact CH2-CG2 3.79Å; W111-V446 HydrophobicContact CZ2-CG2 4.16Å; W111-V446 HydrophobicContact CZ3-CB 4.23Å; W111-V446 HydrophobicContact CZ3-CG1 3.78Å; W111-V446 HydrophobicContact CZ3-CG2 4.21Å; T442-V446 WeakPolarHBondContact O-CG2 3.5Å; G443-V446 PolarHBondContact O-N 2.94Å; I444-V446 VanDerWaalsContact C-N 3.27Å; I444-V446 PolarHBondContact O-N 3.33Å; V446-G450 VanDerWaalsContact O-CA 3.32Å; V446-G450 WeakPolarHBondContact O-CA 3.2Å; V446-G450 PolarHBondContact O-N 3.3Å
447	Y	92.5	Very high	89.9	Confident	39 Å²	39	65.5 Å²	65.5	15%	0.153	37%	0.367	C	S	.	.	H	α-helix	trans	-63.8	-43.9	173.9	177.7	-97.6	0	0	0	112.1	F104 F107 G443 I444 G450 C451 A452	F104-Y447 HydrophobicContact CB-CE1 4.11Å; F104-Y447 AromaticContact CD2-CD1 3.51Å; F104-Y447 HydrophobicContact CD2-CD1 3.51Å; F104-Y447 AromaticContact CD2-CE1 3.67Å; F104-Y447 HydrophobicContact CD2-CE1 3.67Å; F104-Y447 AromaticContact CD2-CG 3.94Å; F104-Y447 HydrophobicContact CD2-CG 3.94Å; F104-Y447 HydrophobicContact CE2-CD1 4.12Å; F104-Y447 HydrophobicContact CE2-CG 4.5Å; F104-Y447 HydrophobicContact CG-CE1 4.37Å; F107-Y447 HydrophobicContact CB-CD2 3.49Å; F107-Y447 VanDerWaalsContact CB-CD2 3.49Å; F107-Y447 HydrophobicContact CB-CE2 3.94Å; F107-Y447 HydrophobicContact CB-CG 4.45Å; F107-Y447 AromaticContact CD1-CD2 3.88Å; F107-Y447 HydrophobicContact CD1-CD2 3.88Å; F107-Y447 HydrophobicContact CD1-CG 4.18Å; F107-Y447 HydrophobicContact CD2-CD2 4.04Å; F107-Y447 AromaticContact CG-CD2 3.51Å; F107-Y447 HydrophobicContact CG-CD2 3.51Å; F107-Y447 HydrophobicContact CG-CE2 4.39Å; F107-Y447 HydrophobicContact CG-CG 4.28Å; G443-Y447 WeakPolarHBondContact O-CB 3.47Å; G443-Y447 PolarHBondContact O-N 2.9Å; I444-Y447 WeakPolarHBondContact O-CB 3.23Å; I444-Y447 PolarHBondContact O-N 2.66Å; Y447-G450 PolarHBondContact O-N 2.96Å; Y447-C451 HydrophobicContact CD2-CB 3.75Å; Y447-C451 HydrophobicContact CE2-CB 3.67Å; Y447-C451 HydrophobicContact CG-CB 4.42Å; Y447-C451 WeakPolarHBondContact O-CA 3.49Å; Y447-C451 WeakPolarHBondContact O-CB 3.34Å; Y447-C451 PolarHBondContact O-N 3.5Å; Y447-A452 HydrophobicContact CD1-CB 4.36Å; Y447-A452 HydrophobicContact CE1-CB 4.06Å; Y447-A452 PolarHBondContact O-N 2.91Å
448	I	92.2	Very high	89.7	Confident	94 Å²	94	70.5 Å²	70.5	48%	0.482	38%	0.384	S	S	.	.	I	π-helix	trans	-62.4	-49.1	-179.2	-67.4	167.7	0	0	0	110	I444 P445 W453	I444-I448 HydrophobicContact CG2-CD1 3.97Å; I444-I448 WeakPolarHBondContact O-CG1 3.46Å; I444-I448 PolarHBondContact O-N 3.2Å; P445-I448 PolarHBondContact O-N 3.36Å; I448-W453 VanDerWaalsContact O-CB 3.31Å; I448-W453 WeakPolarHBondContact O-CB 3.47Å; I448-W453 PolarHBondContact O-N 3.33Å
449	I	90	Very high	89.6	Confident	89 Å²	89	72 Å²	72	46%	0.456	39%	0.392	S	S	.	.	I	π-helix	trans	-70.1	-40.5	-179.9	-63.6	167.4	0	0	0	111.2	P445 W453 K456	P445-I449 WeakPolarHBondContact O-CB 3.34Å; P445-I449 VanDerWaalsContact O-CG1 3.29Å; P445-I449 WeakPolarHBondContact O-CG1 3.4Å; P445-I449 PolarHBondContact O-N 3.04Å; I449-W453 HydrophobicContact CG2-CE3 4.45Å; I449-K456 WeakPolarHBondContact O-CE 3.44Å; I449-K456 PolarHBondContact O-NZ 3.42Å
450	G	87.2	Confident	89.7	Confident	36 Å²	36	74.3 Å²	74.3	37%	0.371	40%	0.4	S	S	.	.	I	π-helix	trans	-79.3	-51.1	-172.5	0	0	0	0	0	113.5	V446 Y447 K456	V446-G450 VanDerWaalsContact O-CA 3.32Å; V446-G450 WeakPolarHBondContact O-CA 3.2Å; V446-G450 PolarHBondContact O-N 3.3Å; Y447-G450 PolarHBondContact O-N 2.96Å; G450-K456 PolarHBondContact O-NZ 3.34Å
451	C	85.1	Confident	89.5	Confident	37 Å²	37	77.2 Å²	77.2	25%	0.25	41%	0.413	C	S	.	.	I	π-helix	trans	-111.2	-46.3	-167.4	-60.4	0	0	0	0	113	Y447	Y447-C451 HydrophobicContact CD2-CB 3.75Å; Y447-C451 HydrophobicContact CE2-CB 3.67Å; Y447-C451 HydrophobicContact CG-CB 4.42Å; Y447-C451 WeakPolarHBondContact O-CA 3.49Å; Y447-C451 WeakPolarHBondContact O-CB 3.34Å; Y447-C451 PolarHBondContact O-N 3.5Å
452	A	86.6	Confident	89.3	Confident	52 Å²	52	82.8 Å²	82.8	43%	0.43	43%	0.426	S	S	.	.	I	π-helix	trans	-74.1	-33.3	-174.7	0	0	0	0	0	112.6	Y447 K454	Y447-A452 HydrophobicContact CD1-CB 4.36Å; Y447-A452 HydrophobicContact CE1-CB 4.06Å; Y447-A452 PolarHBondContact O-N 2.91Å; A452-K454 PolarHBondContact O-N 3.42Å
453	W	86.3	Confident	89.2	Confident	109 Å²	109	87.6 Å²	87.6	41%	0.413	44%	0.441	S	S	.	.			trans	-77	92	-179.8	-170.5	21.3	0	0	0	112.1	I448 I449 N455 K456 P457	I448-W453 VanDerWaalsContact O-CB 3.31Å; I448-W453 WeakPolarHBondContact O-CB 3.47Å; I448-W453 PolarHBondContact O-N 3.33Å; I449-W453 HydrophobicContact CG2-CE3 4.45Å; W453-N455 PolarHBondContact NE1-O 2.98Å; W453-N455 VanDerWaalsContact NE1-O 3.11Å; W453-K456 HydrophobicContact CD2-CG 3.83Å; W453-K456 HydrophobicContact CE3-CG 3.89Å; W453-K456 HydrophobicContact CG-CG 4.11Å; W453-K456 HydrophobicContact CZ3-CG 4.49Å; W453-K456 WeakPolarHBondContact O-CE 3.4Å; W453-K456 WeakPolarHBondContact O-CG 3.39Å; W453-P457 VanDerWaalsContact CH2-CD 3.41Å; W453-P457 HydrophobicContact CH2-CG 4.01Å; W453-P457 HydrophobicContact CZ2-CG 4.06Å
454	K	82.2	Confident	88.9	Confident	183 Å²	183	91.9 Å²	91.9	80%	0.796	46%	0.46	S	S	*	.			trans	-71.8	-39.6	179.1	-63.3	-173.2	179.9	-177.8	0	113.2	A452 K456	A452-K454 PolarHBondContact O-N 3.42Å; K454-K456 PolarHBondContact O-N 3.48Å
455	N	85.5	Confident	88.6	Confident	144 Å²	144	94.5 Å²	94.5	77%	0.77	47%	0.471	S	S	*	.	S	Bend	trans	-95	59.2	-172.7	-64.9	-14.7	0	0	0	112.5	W453	W453-N455 PolarHBondContact NE1-O 2.98Å; W453-N455 VanDerWaalsContact NE1-O 3.11Å
456	K	85.8	Confident	88.4	Confident	51 Å²	51	95.2 Å²	95.2	22%	0.222	48%	0.478	C	S	.	.			trans	-66.9	142.5	178.1	-64.7	172.5	-174.9	171.8	0	110.8	I449 G450 W453 K454 K458 F460 Q461	I449-K456 WeakPolarHBondContact O-CE 3.44Å; I449-K456 PolarHBondContact O-NZ 3.42Å; G450-K456 PolarHBondContact O-NZ 3.34Å; W453-K456 HydrophobicContact CD2-CG 3.83Å; W453-K456 HydrophobicContact CE3-CG 3.89Å; W453-K456 HydrophobicContact CG-CG 4.11Å; W453-K456 HydrophobicContact CZ3-CG 4.49Å; W453-K456 WeakPolarHBondContact O-CE 3.4Å; W453-K456 WeakPolarHBondContact O-CG 3.39Å; K454-K456 PolarHBondContact O-N 3.48Å; K456-K458 PolarHBondContact O-N 3.15Å; K456-F460 HydrophobicContact CB-CD1 4.39Å; K456-F460 HydrophobicContact CD-CD1 4.25Å; K456-F460 HydrophobicContact CD-CE1 4.22Å; K456-Q461 HydrophobicContact CB-CG 3.98Å
457	P	89.1	Confident	88.4	Confident	57 Å²	57	98.1 Å²	98.1	37%	0.37	49%	0.486	S	S	.	.			trans	-54.9	135.3	175.5	-24.7	31.9	0	0	0	111.1	W453 S459 F460 Q461	W453-P457 VanDerWaalsContact CH2-CD 3.41Å; W453-P457 HydrophobicContact CH2-CG 4.01Å; W453-P457 HydrophobicContact CZ2-CG 4.06Å; P457-S459 PolarHBondContact O-N 2.88Å; P457-S459 VanDerWaalsContact O-N 3.12Å; P457-F460 HydrophobicContact CB-CB 4.38Å; P457-F460 WeakPolarHBondContact O-CB 3.42Å; P457-F460 PolarHBondContact O-N 3.08Å; P457-Q461 PolarHBondContact O-N 3.2Å; P457-Q461 VanDerWaalsContact O-N 3.08Å
458	K	87.6	Confident	88.2	Confident	159 Å²	159	97 Å²	97	69%	0.691	48%	0.483	S	S	*	.	H	α-helix	trans	-55.9	-31.7	178.4	-69.5	-174.7	178.5	179.7	0	112.4	K456 R462	K456-K458 PolarHBondContact O-N 3.15Å; K458-R462 WeakPolarHBondContact O-CB 3.29Å; K458-R462 WeakPolarHBondContact O-CG 3.29Å; K458-R462 PolarHBondContact O-N 3.12Å
459	S	90.9	Very high	88.1	Confident	81 Å²	81	95.8 Å²	95.8	57%	0.566	48%	0.477	S	S	*	.	H	α-helix	trans	-63.4	-42.7	174.9	55.1	0	0	0	0	112.5	P457 K463	P457-S459 PolarHBondContact O-N 2.88Å; P457-S459 VanDerWaalsContact O-N 3.12Å; S459-K463 WeakPolarHBondContact O-CG 3.44Å; S459-K463 PolarHBondContact O-N 3.21Å; S459-K463 VanDerWaalsContact O-N 3.08Å
460	F	89.1	Confident	88.2	Confident	92 Å²	92	93.5 Å²	93.5	40%	0.404	48%	0.475	S	S	.	.	H	α-helix	trans	-66.4	-46.7	176.3	179.7	-95.3	0	0	0	111.1	K456 P457 R462 K463 F464	K456-F460 HydrophobicContact CB-CD1 4.39Å; K456-F460 HydrophobicContact CD-CD1 4.25Å; K456-F460 HydrophobicContact CD-CE1 4.22Å; P457-F460 HydrophobicContact CB-CB 4.38Å; P457-F460 WeakPolarHBondContact O-CB 3.42Å; P457-F460 PolarHBondContact O-N 3.08Å; F460-R462 PolarHBondContact O-N 3.25Å; F460-K463 PolarHBondContact O-N 3.4Å; F460-F464 WeakPolarHBondContact O-CB 3.26Å; F460-F464 PolarHBondContact O-N 3.01Å
461	Q	86.5	Confident	88.3	Confident	92 Å²	92	92.8 Å²	92.8	43%	0.43	46%	0.464	S	S	.	.	H	α-helix	trans	-57.9	-46.6	177.1	-69.4	178.9	-15.2	0	0	111.6	K456 P457 K463 F464 E465	K456-Q461 HydrophobicContact CB-CG 3.98Å; P457-Q461 PolarHBondContact O-N 3.2Å; P457-Q461 VanDerWaalsContact O-N 3.08Å; Q461-K463 PolarHBondContact O-N 3.42Å; Q461-F464 PolarHBondContact O-N 3.4Å; Q461-E465 VanDerWaalsContact O-CB 3.3Å; Q461-E465 WeakPolarHBondContact O-CB 3.44Å; Q461-E465 PolarHBondContact O-N 2.89Å
462	R	89.6	Confident	88.5	Confident	176 Å²	176	93.1 Å²	93.1	66%	0.664	46%	0.461	S	S	*	.	H	α-helix	trans	-61.7	-41.3	176.8	-76.5	178.6	179.7	177.3	-0.9	113.2	K458 F460 S466	K458-R462 WeakPolarHBondContact O-CB 3.29Å; K458-R462 WeakPolarHBondContact O-CG 3.29Å; K458-R462 PolarHBondContact O-N 3.12Å; F460-R462 PolarHBondContact O-N 3.25Å; R462-S466 WeakPolarHBondContact O-CB 3.38Å; R462-S466 PolarHBondContact O-N 3.14Å; R462-S466 PolarHBondContact O-OG 2.69Å
463	K	91.5	Very high	88.8	Confident	162 Å²	162	98.5 Å²	98.5	70%	0.704	48%	0.475	S	S	*	.	H	α-helix	trans	-64.9	-44.1	176	-77.8	-174.4	178.7	-173.9	0	111.3	S459 F460 Q461 S466 F467	S459-K463 WeakPolarHBondContact O-CG 3.44Å; S459-K463 PolarHBondContact O-N 3.21Å; S459-K463 VanDerWaalsContact O-N 3.08Å; F460-K463 PolarHBondContact O-N 3.4Å; Q461-K463 PolarHBondContact O-N 3.42Å; K463-S466 PolarHBondContact O-N 3.1Å; K463-F467 WeakPolarHBondContact O-CB 3.46Å; K463-F467 PolarHBondContact O-N 3.03Å
464	F	87.9	Confident	89	Confident	90 Å²	90	99.5 Å²	99.5	40%	0.395	49%	0.488	S	S	.	.	H	α-helix	trans	-65.4	-40.6	178.8	-170.5	-98.2	0	0	0	112.1	P335 F460 Q461 F467 T468	P335-F464 HydrophobicContact CB-CZ 4.11Å; F460-F464 WeakPolarHBondContact O-CB 3.26Å; F460-F464 PolarHBondContact O-N 3.01Å; Q461-F464 PolarHBondContact O-N 3.4Å; F464-F467 PolarHBondContact O-N 3.39Å; F464-T468 WeakPolarHBondContact O-CB 3.45Å; F464-T468 PolarHBondContact O-N 3.32Å; F464-T468 PolarHBondContact O-OG1 3.44Å
465	E	88.4	Confident	89.3	Confident	117 Å²	117	94.1 Å²	94.1	55%	0.547	47%	0.465	S	S	.	.	H	α-helix	trans	-66.2	-43.2	174.6	-170.6	171.1	-160	0	0	111.4	Q461 F467 T468 I469	Q461-E465 VanDerWaalsContact O-CB 3.3Å; Q461-E465 WeakPolarHBondContact O-CB 3.44Å; Q461-E465 PolarHBondContact O-N 2.89Å; E465-F467 VanDerWaalsContact C-N 3.33Å; E465-F467 PolarHBondContact O-N 2.93Å; E465-T468 WeakPolarHBondContact O-CB 3.49Å; E465-T468 PolarHBondContact O-N 3.06Å; E465-T468 VanDerWaalsContact O-N 3.17Å; E465-I469 HydrophobicContact CG-CD1 4.07Å; E465-I469 WeakPolarHBondContact O-CB 3.32Å; E465-I469 VanDerWaalsContact O-CG1 3.3Å; E465-I469 WeakPolarHBondContact O-CG1 3.27Å; E465-I469 PolarHBondContact O-N 3.36Å
466	S	90.9	Very high	89.5	Confident	80 Å²	80	92.6 Å²	92.6	56%	0.559	45%	0.451	S	S	*	.	H	α-helix	trans	-60.8	-41.9	174.3	-60	0	0	0	0	112.1	R462 K463 I469 G470	R462-S466 WeakPolarHBondContact O-CB 3.38Å; R462-S466 PolarHBondContact O-N 3.14Å; R462-S466 PolarHBondContact O-OG 2.69Å; K463-S466 PolarHBondContact O-N 3.1Å; S466-I469 PolarHBondContact O-N 2.69Å; S466-G470 PolarHBondContact O-N 3.41Å
467	F	91.6	Very high	89.5	Confident	121 Å²	121	90.4 Å²	90.4	53%	0.531	44%	0.442	S	S	.	.	H	α-helix	trans	-61.9	-47.5	173.2	175.3	-100.4	0	0	0	111.2	L337 K463 F464 E465 I469 G470 V471	L337-F467 HydrophobicContact CD2-CD1 4.29Å; L337-F467 HydrophobicContact CD2-CE1 3.72Å; K463-F467 WeakPolarHBondContact O-CB 3.46Å; K463-F467 PolarHBondContact O-N 3.03Å; F464-F467 PolarHBondContact O-N 3.39Å; E465-F467 VanDerWaalsContact C-N 3.33Å; E465-F467 PolarHBondContact O-N 2.93Å; F467-I469 PolarHBondContact O-N 3.04Å; F467-G470 PolarHBondContact O-N 2.94Å; F467-G470 VanDerWaalsContact O-N 3.12Å; F467-V471 HydrophobicContact CD1-CG2 4.38Å; F467-V471 HydrophobicContact CD2-CG2 4.41Å; F467-V471 HydrophobicContact CE1-CG2 3.95Å; F467-V471 HydrophobicContact CE2-CG2 3.98Å; F467-V471 HydrophobicContact CZ-CG2 3.74Å; F467-V471 WeakPolarHBondContact O-CG2 3.4Å; F467-V471 PolarHBondContact O-N 3.42Å
468	T	89.4	Confident	89.3	Confident	16 Å²	16	90.2 Å²	90.2	10%	0.098	44%	0.439	C	S	.	.	H	α-helix	trans	-58	-47.3	178.2	-58.6	0	0	0	0	111	L337 F340 F464 E465 G470 V471 Q472	L337-T468 HydrophobicContact CB-CG2 4.31Å; L337-T468 HydrophobicContact CD1-CG2 4.22Å; F340-T468 HydrophobicContact CE2-CG2 3.71Å; F340-T468 HydrophobicContact CZ-CG2 4.25Å; F464-T468 WeakPolarHBondContact O-CB 3.45Å; F464-T468 PolarHBondContact O-N 3.32Å; F464-T468 PolarHBondContact O-OG1 3.44Å; E465-T468 WeakPolarHBondContact O-CB 3.49Å; E465-T468 PolarHBondContact O-N 3.06Å; E465-T468 VanDerWaalsContact O-N 3.17Å; T468-G470 VanDerWaalsContact C-N 3.34Å; T468-G470 PolarHBondContact O-N 3.22Å; T468-V471 PolarHBondContact O-N 3.24Å; T468-Q472 WeakPolarHBondContact O-CB 3.28Å; T468-Q472 VanDerWaalsContact O-CG 3.31Å; T468-Q472 WeakPolarHBondContact O-CG 3.37Å; T468-Q472 PolarHBondContact O-N 2.99Å
469	I	89.6	Confident	89	Confident	68 Å²	68	86 Å²	86	35%	0.349	43%	0.429	S	S	.	.	H	α-helix	trans	-63.3	-39.4	176.3	-67.7	167.7	0	0	0	111.1	E465 S466 F467 Q472 K473	E465-I469 HydrophobicContact CG-CD1 4.07Å; E465-I469 WeakPolarHBondContact O-CB 3.32Å; E465-I469 VanDerWaalsContact O-CG1 3.3Å; E465-I469 WeakPolarHBondContact O-CG1 3.27Å; E465-I469 PolarHBondContact O-N 3.36Å; S466-I469 PolarHBondContact O-N 2.69Å; F467-I469 PolarHBondContact O-N 3.04Å; I469-Q472 PolarHBondContact O-N 3.43Å; I469-K473 HydrophobicContact CG2-CD 4.19Å; I469-K473 HydrophobicContact CG2-CG 4.46Å; I469-K473 WeakPolarHBondContact O-CG 3.4Å; I469-K473 PolarHBondContact O-N 3.5Å
470	G	91.7	Very high	87.9	Confident	40 Å²	40	84 Å²	84	41%	0.412	41%	0.414	S	S	.	.	H	α-helix	trans	-59.3	-47.9	175.6	0	0	0	0	0	112	S466 F467 T468 K473 L474	S466-G470 PolarHBondContact O-N 3.41Å; F467-G470 PolarHBondContact O-N 2.94Å; F467-G470 VanDerWaalsContact O-N 3.12Å; T468-G470 VanDerWaalsContact C-N 3.34Å; T468-G470 PolarHBondContact O-N 3.22Å; G470-K473 PolarHBondContact O-N 2.95Å; G470-L474 WeakPolarHBondContact O-CB 3.27Å; G470-L474 PolarHBondContact O-N 2.95Å
471	V	90	Very high	86.3	Confident	22 Å²	22	90.4 Å²	90.4	13%	0.133	45%	0.453	C	S	.	.	H	α-helix	trans	-67.7	-38.1	177.2	-176.9	0	0	0	0	111.3	L337 F467 T468 K473 L474 F475 L477	L337-V471 HydrophobicContact CD1-CB 3.76Å; L337-V471 HydrophobicContact CD1-CG1 3.66Å; L337-V471 HydrophobicContact CD2-CB 4.12Å; L337-V471 HydrophobicContact CD2-CG1 4.12Å; L337-V471 HydrophobicContact CD2-CG2 4.13Å; L337-V471 HydrophobicContact CG-CG1 4.33Å; F467-V471 HydrophobicContact CD1-CG2 4.38Å; F467-V471 HydrophobicContact CD2-CG2 4.41Å; F467-V471 HydrophobicContact CE1-CG2 3.95Å; F467-V471 HydrophobicContact CE2-CG2 3.98Å; F467-V471 HydrophobicContact CZ-CG2 3.74Å; F467-V471 WeakPolarHBondContact O-CG2 3.4Å; F467-V471 PolarHBondContact O-N 3.42Å; T468-V471 PolarHBondContact O-N 3.24Å; V471-K473 PolarHBondContact O-N 3.19Å; V471-L474 PolarHBondContact O-N 3.42Å; V471-F475 HydrophobicContact CG1-CD2 3.67Å; V471-F475 HydrophobicContact CG1-CE2 4.1Å; V471-F475 PolarHBondContact O-N 3.47Å; V471-L477 HydrophobicContact CG1-CD1 4.22Å
472	Q	89.5	Confident	86.3	Confident	44 Å²	44	90.4 Å²	90.4	21%	0.206	45%	0.454	C	S	.	.	H	α-helix	trans	-59.4	-43.8	173.3	-77.3	179.6	-67.5	0	0	112.3	F340 T468 I469 K476 L477	F340-Q472 HydrophobicContact CD2-CG 3.52Å; F340-Q472 HydrophobicContact CE2-CG 3.5Å; F340-Q472 VanDerWaalsContact CE2-CG 3.5Å; T468-Q472 WeakPolarHBondContact O-CB 3.28Å; T468-Q472 VanDerWaalsContact O-CG 3.31Å; T468-Q472 WeakPolarHBondContact O-CG 3.37Å; T468-Q472 PolarHBondContact O-N 2.99Å; I469-Q472 PolarHBondContact O-N 3.43Å; Q472-K476 CarbonylContact O-C 3.48Å; Q472-K476 WeakPolarHBondContact O-CA 3.47Å; Q472-K476 PolarHBondContact O-N 2.96Å; Q472-L477 HydrophobicContact CG-CB 4.31Å; Q472-L477 PolarHBondContact O-N 3.05Å
473	K	90.9	Very high	86.2	Confident	164 Å²	164	85.8 Å²	85.8	71%	0.713	44%	0.443	S	S	*	.	H	α-helix	trans	-68.6	-42.6	177.3	-72.6	179	-179.8	-177.1	0	111.8	I469 G470 V471	I469-K473 HydrophobicContact CG2-CD 4.19Å; I469-K473 HydrophobicContact CG2-CG 4.46Å; I469-K473 WeakPolarHBondContact O-CG 3.4Å; I469-K473 PolarHBondContact O-N 3.5Å; G470-K473 PolarHBondContact O-N 2.95Å; V471-K473 PolarHBondContact O-N 3.19Å
474	L	91.1	Very high	85.9	Confident	130 Å²	130	81.6 Å²	81.6	68%	0.681	43%	0.428	S	S	*	.	H	α-helix	trans	-61.2	-46.4	-179.2	-177.8	66.4	0	0	0	112	G470 V471	G470-L474 WeakPolarHBondContact O-CB 3.27Å; G470-L474 PolarHBondContact O-N 2.95Å; V471-L474 PolarHBondContact O-N 3.42Å
475	F	88.2	Confident	85.7	Confident	71 Å²	71	81.1 Å²	81.1	31%	0.311	43%	0.43	S	S	.	.	T	Hydrogen-bonded Turn	trans	-104.4	10.9	-176.1	-66.6	-60.6	0	0	0	113.9	H342 I349 V471 L477	H342-F475 PolarHBondContact CD2-O 3.4Å; I349-F475 HydrophobicContact CG2-CD1 4.1Å; I349-F475 HydrophobicContact CG2-CE1 4.45Å; I349-F475 HydrophobicContact CG2-CG 4.3Å; V471-F475 HydrophobicContact CG1-CD2 3.67Å; V471-F475 HydrophobicContact CG1-CE2 4.1Å; V471-F475 PolarHBondContact O-N 3.47Å; F475-L477 VanDerWaalsContact C-N 3.32Å; F475-L477 HydrophobicContact CB-CD1 3.84Å; F475-L477 HydrophobicContact CB-CD2 3.9Å; F475-L477 HydrophobicContact CB-CG 3.59Å; F475-L477 HydrophobicContact CD2-CD1 4.48Å; F475-L477 PolarHBondContact O-N 3.29Å
476	K	89.5	Confident	85.6	Confident	111 Å²	111	78.9 Å²	78.9	48%	0.483	42%	0.423	S	S	.	.	T	Hydrogen-bonded Turn	trans	49.2	50.3	-178	-65.1	-174.1	-178.4	-177.1	0	112.9	M343 Q472	M343-K476 HydrophobicContact CE-CB 3.62Å; M343-K476 HydrophobicContact CE-CG 4.16Å; M343-K476 WeakPolarHBondContact CG-O 3.32Å; M343-K476 PolarHBondContact N-O 3.18Å; Q472-K476 CarbonylContact O-C 3.48Å; Q472-K476 WeakPolarHBondContact O-CA 3.47Å; Q472-K476 PolarHBondContact O-N 2.96Å
477	L	87	Confident	85.2	Confident	6 Å²	6	78.8 Å²	78.8	3%	0.031	41%	0.414	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.2	139.3	-173.8	-54.3	172.6	0	0	0	112.5	L337 F340 L341 H342 I349 V471 Q472 F475	L337-L477 HydrophobicContact CD1-CD1 4.39Å; F340-L477 HydrophobicContact CB-CB 3.65Å; F340-L477 HydrophobicContact CB-CD1 4.33Å; F340-L477 HydrophobicContact CB-CG 4.46Å; F340-L477 HydrophobicContact CD2-CB 4.26Å; F340-L477 HydrophobicContact CG-CB 4.45Å; L341-L477 CarbonylContact O-C 3.53Å; L341-L477 WeakPolarHBondContact O-CA 3.39Å; H342-L477 HydrophobicContact CB-CD2 4.3Å; I349-L477 HydrophobicContact CB-CD2 4.22Å; V471-L477 HydrophobicContact CG1-CD1 4.22Å; Q472-L477 HydrophobicContact CG-CB 4.31Å; Q472-L477 PolarHBondContact O-N 3.05Å; F475-L477 VanDerWaalsContact C-N 3.32Å; F475-L477 HydrophobicContact CB-CD1 3.84Å; F475-L477 HydrophobicContact CB-CD2 3.9Å; F475-L477 HydrophobicContact CB-CG 3.59Å; F475-L477 HydrophobicContact CD2-CD1 4.48Å; F475-L477 PolarHBondContact O-N 3.29Å
478	V	85.1	Confident	84.8	Confident	52 Å²	52	75.8 Å²	75.8	32%	0.315	41%	0.406	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-123.3	149.1	175.6	-74.2	0	0	0	0	111.7	F340 L341 M343	F340-V478 CarbonylContact C-O 3.48Å; F340-V478 VanDerWaalsContact CA-O 3.28Å; F340-V478 WeakPolarHBondContact CA-O 3.39Å; F340-V478 WeakPolarHBondContact CB-O 3.42Å; L341-V478 PolarHBondContact N-O 2.87Å; L341-V478 WeakPolarHBondContact O-CG2 3.46Å; L341-V478 PolarHBondContact O-N 3.11Å; M343-V478 HydrophobicContact CG-CB 4.22Å; M343-V478 HydrophobicContact CG-CG1 3.42Å; M343-V478 VanDerWaalsContact CG-CG1 3.42Å; M343-V478 HydrophobicContact CG-CG2 3.8Å; M343-V478 HydrophobicContact SD-CG1 3.73Å
479	P	79.7	Confident	84.4	Confident	72 Å²	72	80.4 Å²	80.4	47%	0.468	43%	0.429	S	S	.	.			trans	-60.3	141.6	170.7	-15.6	29.1	0	0	0	110.9	F340	F340-P479 HydrophobicContact CD1-CB 4.18Å; F340-P479 HydrophobicContact CD1-CG 4.38Å; F340-P479 HydrophobicContact CE1-CB 3.93Å; F340-P479 HydrophobicContact CE1-CG 3.93Å; F340-P479 HydrophobicContact CZ-CG 4.34Å
480	S	68	Low	84	Confident	38 Å²	38	81.4 Å²	81.4	27%	0.266	44%	0.436	S	S	.	.			trans	-76.4	127.8	164.9	58.5	0	0	0	0	109.5	F326	F326-S480 WeakPolarHBondContact CE2-OG 3.43Å
481	N	57.1	Low	83.3	Confident	227 Å²	227	85.2 Å²	85.2	100%	1.214	44%	0.438	S	S	*	.			trans	-69.8	0	175.7	-76.6	-13.3	0	0	0	112.6

Retrieved 481 of 481 residues in 1119.2 ms (Link to these results)

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