A0A5K4F0R0_SCHMA Loading...

Innexin AlphaSync

Structural component of the gap junctions.

AlphaFold DB , UniProt , Accession A0A5K4F0R0, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene inx, Length 395 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure AlphaSync Parameters PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	45.7	Very low	55.7	Low	225 Å²	225	112.8 Å²	112.8	100%	1.108	61%	0.608	S	S	*	*				0	116.1	0	-83.8	178.9	163.2	0	0	107.6	A3	M1-A3 PolarHBondContact O-N 2.94Å
2	D	62.6	Low	55.3	Low	112 Å²	112	106.3 Å²	106.3	60%	0.599	57%	0.572	S	S	*	*			trans	-59.3	135	179.3	-62.1	-31.6	0	0	0	111	N4 N5 A6	D2-N4 PolarHBondContact O-N 3.3Å; D2-N4 VanDerWaalsContact O-N 3.1Å; D2-N5 HydrophobicContact CB-CB 4.44Å; D2-N5 WeakPolarHBondContact O-CA 3.47Å; D2-N5 WeakPolarHBondContact O-CB 3.46Å; D2-N5 PolarHBondContact O-N 3.01Å; D2-A6 PolarHBondContact O-N 3.37Å
3	A	64.1	Low	55.3	Low	80 Å²	80	105.5 Å²	105.5	66%	0.661	56%	0.56	S	S	*	*	H	α-helix	trans	-53.8	-33.2	178.5	0	0	0	0	0	112.2	M1 N5 A6 L7	M1-A3 PolarHBondContact O-N 2.94Å; A3-N5 PolarHBondContact O-N 3.37Å; A3-A6 PolarHBondContact O-N 3.1Å; A3-L7 VanDerWaalsContact O-CB 3.25Å; A3-L7 WeakPolarHBondContact O-CB 3.42Å; A3-L7 PolarHBondContact O-N 3.14Å
4	N	64.6	Low	54.9	Low	125 Å²	125	113.3 Å²	113.3	67%	0.668	58%	0.578	S	S	*	*	H	α-helix	trans	-64.4	-36.1	173.6	-80.7	-19.4	0	0	0	113.4	D2 K8	D2-N4 PolarHBondContact O-N 3.3Å; D2-N4 VanDerWaalsContact O-N 3.1Å; N4-K8 WeakPolarHBondContact O-CB 3.1Å; N4-K8 VanDerWaalsContact O-CG 3.22Å; N4-K8 WeakPolarHBondContact O-CG 3.08Å; N4-K8 PolarHBondContact O-N 3.49Å
5	N	62.9	Low	54.7	Low	87 Å²	87	107.1 Å²	107.1	47%	0.465	55%	0.548	S	S	.	.	H	α-helix	trans	-75.5	-38.5	177.5	-68.7	-21.8	0	0	0	111	D2 A3 K8 L9	D2-N5 HydrophobicContact CB-CB 4.44Å; D2-N5 WeakPolarHBondContact O-CA 3.47Å; D2-N5 WeakPolarHBondContact O-CB 3.46Å; D2-N5 PolarHBondContact O-N 3.01Å; A3-N5 PolarHBondContact O-N 3.37Å; N5-K8 PolarHBondContact O-N 2.96Å; N5-L9 WeakPolarHBondContact O-CB 3.4Å; N5-L9 PolarHBondContact O-N 3.48Å
6	A	50	Low	54.3	Low	52 Å²	52	105.5 Å²	105.5	43%	0.43	55%	0.547	S	S	.	.	H	α-helix	trans	-64.2	-40.3	172.7	0	0	0	0	0	112	D2 A3 L9 G10	D2-A6 PolarHBondContact O-N 3.37Å; A3-A6 PolarHBondContact O-N 3.1Å; A6-L9 CarbonylContact O-C 3.57Å; A6-L9 WeakPolarHBondContact O-CB 3.15Å; A6-L9 PolarHBondContact O-N 2.92Å; A6-G10 PolarHBondContact O-N 3.37Å
7	L	52.4	Low	53.3	Low	102 Å²	102	111.4 Å²	111.4	53%	0.534	56%	0.562	S	S	.	*	H	α-helix	trans	-71.6	-33.9	178	-155.5	132.5	0	0	0	112	A3 G10 R11	A3-L7 VanDerWaalsContact O-CB 3.25Å; A3-L7 WeakPolarHBondContact O-CB 3.42Å; A3-L7 PolarHBondContact O-N 3.14Å; L7-G10 PolarHBondContact O-N 3.48Å; L7-R11 WeakPolarHBondContact O-CG 3.48Å; L7-R11 PolarHBondContact O-N 3.23Å
8	K	56.2	Low	52.8	Low	145 Å²	145	107 Å²	107	63%	0.63	55%	0.549	S	S	*	.	H	α-helix	trans	-63.7	-40.9	168.2	-78.6	173.1	-176.2	174.9	0	111.8	N4 N5 R11 L12	N4-K8 WeakPolarHBondContact O-CB 3.1Å; N4-K8 VanDerWaalsContact O-CG 3.22Å; N4-K8 WeakPolarHBondContact O-CG 3.08Å; N4-K8 PolarHBondContact O-N 3.49Å; N5-K8 PolarHBondContact O-N 2.96Å; K8-R11 PolarHBondContact O-N 3.35Å; K8-L12 PolarHBondContact O-N 2.82Å
9	L	52.5	Low	52.7	Low	94 Å²	94	101.6 Å²	101.6	49%	0.492	52%	0.523	S	S	.	.	H	α-helix	trans	-67.6	-40.3	175.3	-169.1	69.4	0	0	0	111.6	N5 A6 R11 L12 F13	N5-L9 WeakPolarHBondContact O-CB 3.4Å; N5-L9 PolarHBondContact O-N 3.48Å; A6-L9 CarbonylContact O-C 3.57Å; A6-L9 WeakPolarHBondContact O-CB 3.15Å; A6-L9 PolarHBondContact O-N 2.92Å; L9-R11 VanDerWaalsContact C-N 3.32Å; L9-R11 PolarHBondContact O-N 3.02Å; L9-L12 HydrophobicContact CD1-CD2 4.1Å; L9-L12 WeakPolarHBondContact O-CA 3.47Å; L9-L12 WeakPolarHBondContact O-CB 3.21Å; L9-L12 PolarHBondContact O-N 3.39Å; L9-F13 HydrophobicContact CD1-CE2 4.47Å; L9-F13 HydrophobicContact CG-CE2 4.13Å; L9-F13 WeakPolarHBondContact O-CD2 3.46Å
10	G	46.3	Very low	52.9	Low	41 Å²	41	98.7 Å²	98.7	42%	0.423	51%	0.507	S	S	.	.	H	α-helix	trans	-64.3	-34.3	176.2	0	0	0	0	0	113.3	A6 L7 L12 F13 R14	A6-G10 PolarHBondContact O-N 3.37Å; L7-G10 PolarHBondContact O-N 3.48Å; G10-L12 PolarHBondContact O-N 3.3Å; G10-F13 PolarHBondContact O-N 2.9Å; G10-R14 PolarHBondContact O-N 3.43Å
11	R	55.4	Low	53.2	Low	178 Å²	178	94.2 Å²	94.2	67%	0.672	49%	0.485	S	S	*	.	H	α-helix	trans	-65.2	-25.5	170.4	-73.4	-179.9	-173.4	-174.8	2.6	112.9	L7 K8 L9 F13 R14	L7-R11 WeakPolarHBondContact O-CG 3.48Å; L7-R11 PolarHBondContact O-N 3.23Å; K8-R11 PolarHBondContact O-N 3.35Å; L9-R11 VanDerWaalsContact C-N 3.32Å; L9-R11 PolarHBondContact O-N 3.02Å; R11-F13 VanDerWaalsContact C-N 3.28Å; R11-F13 PolarHBondContact O-N 3.22Å; R11-R14 PolarHBondContact O-N 2.79Å
12	L	51.3	Low	54.3	Low	34 Å²	34	83.7 Å²	83.7	18%	0.178	43%	0.434	C	S	.	.	H	α-helix	trans	-66.3	-31.7	174.7	-162.6	74.3	0	0	0	111.8	K8 L9 G10 V123 R126	K8-L12 PolarHBondContact O-N 2.82Å; L9-L12 HydrophobicContact CD1-CD2 4.1Å; L9-L12 WeakPolarHBondContact O-CA 3.47Å; L9-L12 WeakPolarHBondContact O-CB 3.21Å; L9-L12 PolarHBondContact O-N 3.39Å; G10-L12 PolarHBondContact O-N 3.3Å; L12-V123 HydrophobicContact CD2-CB 4.43Å; L12-V123 HydrophobicContact CD2-CG1 3.97Å; L12-V123 HydrophobicContact CD2-CG2 3.73Å; L12-V123 HydrophobicContact CG-CG2 4.41Å; L12-R126 HydrophobicContact CD1-CB 4.32Å
13	F	54.7	Low	55.2	Low	96 Å²	96	78.6 Å²	78.6	42%	0.421	41%	0.406	S	S	.	.	H	α-helix	trans	-90.1	-13.7	-179.9	-69	-72.4	0	0	0	114	L9 G10 R11 V15 W119	L9-F13 HydrophobicContact CD1-CE2 4.47Å; L9-F13 HydrophobicContact CG-CE2 4.13Å; L9-F13 WeakPolarHBondContact O-CD2 3.46Å; G10-F13 PolarHBondContact O-N 2.9Å; R11-F13 VanDerWaalsContact C-N 3.28Å; R11-F13 PolarHBondContact O-N 3.22Å; F13-V15 PolarHBondContact O-N 3.26Å; F13-V15 VanDerWaalsContact O-N 3.12Å; F13-W119 HydrophobicContact CB-CH2 4.46Å; F13-W119 AromaticContact CD1-CD2 3.77Å; F13-W119 HydrophobicContact CD1-CD2 3.77Å; F13-W119 AromaticContact CD1-CE3 3.65Å; F13-W119 HydrophobicContact CD1-CE3 3.65Å; F13-W119 HydrophobicContact CD1-CG 4.41Å; F13-W119 HydrophobicContact CD1-CH2 4.14Å; F13-W119 HydrophobicContact CD1-CZ2 4.25Å; F13-W119 AromaticContact CD1-CZ3 3.85Å; F13-W119 HydrophobicContact CD1-CZ3 3.85Å; F13-W119 HydrophobicContact CE1-CB 4.35Å; F13-W119 AromaticContact CE1-CD2 3.91Å; F13-W119 HydrophobicContact CE1-CD2 3.91Å; F13-W119 AromaticContact CE1-CE3 3.96Å; F13-W119 HydrophobicContact CE1-CE3 3.96Å; F13-W119 HydrophobicContact CE1-CG 4.09Å; F13-W119 WeakPolarHBondContact O-CH2 3.31Å
14	R	49.3	Very low	56.3	Low	215 Å²	215	80.7 Å²	80.7	81%	0.811	40%	0.4	S	S	*	.			trans	-84.8	86.9	-177.5	-156.1	-179.5	-165.5	-176	4.9	110.4	G10 R11	G10-R14 PolarHBondContact O-N 3.43Å; R11-R14 PolarHBondContact O-N 2.79Å
15	V	51.9	Low	57.4	Low	21 Å²	21	75.8 Å²	75.8	13%	0.127	38%	0.375	C	S	.	.	P	Polyproline II helix	trans	-102.1	119.5	-179.3	-177.8	0	0	0	0	110.2	F13 Y30 W119	F13-V15 PolarHBondContact O-N 3.26Å; F13-V15 VanDerWaalsContact O-N 3.12Å; V15-Y30 HydrophobicContact CG1-CE2 4.29Å; V15-Y30 HydrophobicContact CG2-CE2 4.15Å; V15-W119 HydrophobicContact CB-CH2 4.5Å; V15-W119 HydrophobicContact CG2-CH2 3.65Å; V15-W119 HydrophobicContact CG2-CZ3 3.94Å
16	P	49.5	Very low	58.7	Low	81 Å²	81	72.1 Å²	72.1	53%	0.526	36%	0.356	S	S	.	.	P	Polyproline II helix	trans	-66.6	155.8	175.2	26.6	-32.3	0	0	0	111.7	G18 G19	P16-G18 PolarHBondContact O-N 2.93Å; P16-G19 PolarHBondContact O-N 2.83Å
17	Y	36.7	Very low	60.5	Low	206 Å²	206	70.2 Å²	70.2	81%	0.808	34%	0.338	S	S	*	.	T	Hydrogen-bonded Turn	trans	-52.9	125.2	175.3	-130	-95.7	0	0	0	110.1	R140	Y17-R140 PolarHBondContact O-NH2 2.85Å
18	G	44.9	Very low	62.3	Low	32 Å²	32	66.5 Å²	66.5	33%	0.33	32%	0.318	S	S	.	.	T	Hydrogen-bonded Turn	trans	88.7	3.9	-173	0	0	0	0	0	115.9	P16 Q27 R140	P16-G18 PolarHBondContact O-N 2.93Å; G18-Q27 VanDerWaalsContact C-NE2 3.32Å; G18-Q27 PolarHBondContact O-NE2 3.37Å; G18-Q27 PolarHBondContact O-OE1 3.12Å; G18-R140 VanDerWaalsContact C-NH1 3.26Å; G18-R140 PolarHBondContact O-NH1 3.27Å; G18-R140 PolarHBondContact O-NH2 2.94Å
19	G	49.2	Very low	64	Low	5 Å²	5	59.6 Å²	59.6	5%	0.052	29%	0.288	C	S	.	.			trans	60.2	156.7	154.1	0	0	0	0	0	121.4	P16 G21 Q27 R140	P16-G19 PolarHBondContact O-N 2.83Å; G19-G21 VanDerWaalsContact C-N 3.32Å; G19-Q27 VanDerWaalsContact CA-NE2 3.27Å; G19-Q27 PolarHBondContact O-NE2 3.04Å; G19-R140 PolarHBondContact O-NH1 3.04Å
20	E	57.7	Low	65.8	Low	43 Å²	43	55.1 Å²	55.1	20%	0.201	27%	0.265	C	S	.	.	S	Bend	trans	-90	3.1	173.6	-60.5	-176.5	122.5	0	0	112.8	R126	E20-R126 VanDerWaalsContact CD-CZ 3.41Å; E20-R126 VanDerWaalsContact CD-NH2 3.29Å; E20-R126 IonicContact OE1-CZ 2.61Å; E20-R126 IonicContact OE1-NH1 3.39Å; E20-R126 PolarHBondContact OE1-NH1 3.4Å; E20-R126 IonicContact OE1-NH2 2.6Å; E20-R126 PolarHBondContact OE1-NH2 3.46Å; E20-R126 IonicContact OE2-CZ 3.78Å; E20-R126 IonicContact OE2-NE 2.89Å; E20-R126 IonicContact OE2-NH1 2.71Å; E20-R126 PolarHBondContact OE2-NH1 3.25Å; E20-R126 IonicContact OE2-NH2 3.9Å; E20-R126 PolarHBondContact OE2-NH2 3.11Å
21	G	58.2	Low	67.8	Low	5 Å²	5	55.1 Å²	55.1	5%	0.052	25%	0.254	C	S	.	.	S	Bend	trans	-71.7	150.2	175.8	0	0	0	0	0	112.1	G19 D23	G19-G21 VanDerWaalsContact C-N 3.32Å; G21-D23 PolarHBondContact O-N 2.78Å
22	V	70	Confident	69.5	Low	4 Å²	4	49.8 Å²	49.8	2%	0.024	24%	0.236	C	C	.	.	S	Bend	trans	-64.4	-32	176	-177.1	0	0	0	0	111	W125 L136 F195 W302 F348 A352	V22-W125 HydrophobicContact CG2-CZ2 3.86Å; V22-L136 HydrophobicContact CG2-CD1 3.88Å; V22-F195 HydrophobicContact CB-CE2 3.86Å; V22-F195 HydrophobicContact CB-CZ 4.37Å; V22-F195 HydrophobicContact CG1-CE2 4.08Å; V22-F195 HydrophobicContact CG1-CZ 4.18Å; V22-F195 HydrophobicContact CG2-CD2 4.35Å; V22-F195 HydrophobicContact CG2-CE2 3.86Å; V22-W302 HydrophobicContact CG1-CH2 4.16Å; V22-W302 HydrophobicContact CG1-CZ2 3.89Å; V22-F348 HydrophobicContact CG2-CZ 4.48Å; V22-A352 HydrophobicContact CG1-CB 3.72Å
23	D	81.6	Confident	71.5	Confident	4 Å²	4	48.2 Å²	48.2	2%	0.021	23%	0.228	C	C	.	.	S	Bend	trans	-132	148.2	-176.4	-69.4	-76.4	0	0	0	112.5	G21 V25 D26 Q27 R199 W302 K355	G21-D23 PolarHBondContact O-N 2.78Å; D23-V25 PolarHBondContact O-N 3.12Å; D23-D26 PolarHBondContact O-N 2.84Å; D23-D26 VanDerWaalsContact O-N 3.11Å; D23-Q27 WeakPolarHBondContact O-CG 3.43Å; D23-Q27 PolarHBondContact O-N 3.26Å; D23-R199 IonicContact OD2-CZ 3.41Å; D23-R199 IonicContact OD2-NH2 3.82Å; D23-R199 PolarHBondContact OD2-NH2 2.97Å; D23-W302 VanDerWaalsContact CG-NE1 3.3Å; D23-W302 PolarHBondContact OD1-NE1 3.28Å; D23-W302 VanDerWaalsContact OD1-NE1 3.11Å; D23-W302 VanDerWaalsContact OD2-CE2 3.32Å; D23-W302 PolarHBondContact OD2-NE1 3.44Å; D23-K355 WeakPolarHBondContact OD1-CD 3.42Å; D23-K355 VanDerWaalsContact OD1-CE 3.26Å; D23-K355 WeakPolarHBondContact OD1-CE 3.44Å; D23-K355 IonicContact OD1-NZ 3.73Å; D23-K355 PolarHBondContact OD1-NZ 3.49Å
24	F	85.8	Confident	73.3	Confident	124 Å²	124	44.3 Å²	44.3	54%	0.544	21%	0.212	S	C	.	.	H	α-helix	trans	-57.4	-36.6	172.5	-179.4	-111.9	0	0	0	112.8	D26 Q27 L28 F32	F24-D26 VanDerWaalsContact C-N 3.28Å; F24-D26 PolarHBondContact O-N 2.78Å; F24-Q27 WeakPolarHBondContact O-CA 3.33Å; F24-Q27 VanDerWaalsContact O-CB 3.32Å; F24-Q27 WeakPolarHBondContact O-CB 3.37Å; F24-Q27 PolarHBondContact O-N 3.28Å; F24-Q27 VanDerWaalsContact O-N 3.08Å; F24-L28 HydrophobicContact CD1-CD1 4Å; F24-L28 HydrophobicContact CD1-CG 4.16Å; F24-L28 HydrophobicContact CE1-CD1 3.69Å; F24-L28 HydrophobicContact CE1-CD2 3.84Å; F24-L28 HydrophobicContact CE1-CG 3.8Å; F24-L28 HydrophobicContact CE2-CD2 4.42Å; F24-L28 HydrophobicContact CZ-CD1 4.41Å; F24-L28 HydrophobicContact CZ-CD2 3.7Å; F24-L28 HydrophobicContact CZ-CG 4.06Å; F24-L28 PolarHBondContact O-N 3.41Å; F24-F32 HydrophobicContact CE2-CE2 4.18Å; F24-F32 HydrophobicContact CE2-CZ 4.43Å
25	V	89.6	Confident	75.3	Confident	23 Å²	23	35.9 Å²	35.9	14%	0.139	19%	0.192	C	C	.	.	H	α-helix	trans	-61.5	-38.4	177.7	179.7	0	0	0	0	111.3	D23 Q27 L28 N29 L294 T295 N298	D23-V25 PolarHBondContact O-N 3.12Å; V25-Q27 VanDerWaalsContact C-N 3.28Å; V25-Q27 PolarHBondContact O-N 3.44Å; V25-L28 WeakPolarHBondContact O-CB 3.35Å; V25-L28 PolarHBondContact O-N 3.1Å; V25-N29 PolarHBondContact O-N 3.06Å; V25-N29 PolarHBondContact O-ND2 3.02Å; V25-L294 HydrophobicContact CG1-CB 4.27Å; V25-T295 HydrophobicContact CG1-CG2 3.73Å; V25-N298 HydrophobicContact CB-CB 4.34Å; V25-N298 WeakPolarHBondContact CB-ND2 3.23Å; V25-N298 HydrophobicContact CG1-CB 4.3Å; V25-N298 HydrophobicContact CG2-CB 4.03Å
26	D	88.7	Confident	77.3	Confident	10 Å²	10	36.5 Å²	36.5	5%	0.053	19%	0.194	C	C	.	.	H	α-helix	trans	-64.6	-40.5	177.3	-56.4	-17	0	0	0	109.5	D23 F24 L28 N29 Y30 R199 F202	D23-D26 PolarHBondContact O-N 2.84Å; D23-D26 VanDerWaalsContact O-N 3.11Å; F24-D26 VanDerWaalsContact C-N 3.28Å; F24-D26 PolarHBondContact O-N 2.78Å; D26-L28 VanDerWaalsContact C-N 3.33Å; D26-L28 PolarHBondContact O-N 2.78Å; D26-N29 WeakPolarHBondContact O-CB 3.38Å; D26-N29 PolarHBondContact O-N 3Å; D26-Y30 HydrophobicContact CB-CE1 4.46Å; D26-Y30 WeakPolarHBondContact O-CD1 3.36Å; D26-Y30 VanDerWaalsContact O-CE1 3.3Å; D26-Y30 WeakPolarHBondContact O-CE1 3.48Å; D26-Y30 PolarHBondContact O-N 3.39Å; D26-Y30 VanDerWaalsContact O-N 3.12Å; D26-R199 IonicContact OD1-NH2 2.72Å; D26-F202 HydrophobicContact CB-CE2 4.32Å; D26-F202 HydrophobicContact CB-CZ 4.22Å
27	Q	87.8	Confident	79.5	Confident	12 Å²	12	32.6 Å²	32.6	6%	0.056	17%	0.169	C	C	.	.	H	α-helix	trans	-60	-40.6	174.7	-50	-177	5	0	0	112.1	G18 G19 D23 F24 V25 N29 Y30 Q31 F32	G18-Q27 VanDerWaalsContact C-NE2 3.32Å; G18-Q27 PolarHBondContact O-NE2 3.37Å; G18-Q27 PolarHBondContact O-OE1 3.12Å; G19-Q27 VanDerWaalsContact CA-NE2 3.27Å; G19-Q27 PolarHBondContact O-NE2 3.04Å; D23-Q27 WeakPolarHBondContact O-CG 3.43Å; D23-Q27 PolarHBondContact O-N 3.26Å; F24-Q27 WeakPolarHBondContact O-CA 3.33Å; F24-Q27 VanDerWaalsContact O-CB 3.32Å; F24-Q27 WeakPolarHBondContact O-CB 3.37Å; F24-Q27 PolarHBondContact O-N 3.28Å; F24-Q27 VanDerWaalsContact O-N 3.08Å; V25-Q27 VanDerWaalsContact C-N 3.28Å; V25-Q27 PolarHBondContact O-N 3.44Å; Q27-N29 VanDerWaalsContact C-N 3.26Å; Q27-N29 PolarHBondContact O-N 3.49Å; Q27-Y30 VanDerWaalsContact CA-CE1 3.41Å; Q27-Y30 HydrophobicContact CB-CE1 4.29Å; Q27-Y30 HydrophobicContact CG-CE1 4.24Å; Q27-Y30 WeakPolarHBondContact CG-OH 3.28Å; Q27-Q31 WeakPolarHBondContact O-CA 3.35Å; Q27-Q31 VanDerWaalsContact O-CB 3.24Å; Q27-Q31 WeakPolarHBondContact O-CB 2.96Å; Q27-Q31 PolarHBondContact O-N 2.78Å; Q27-F32 PolarHBondContact O-N 3.39Å
28	L	90.8	Very high	82.2	Confident	23 Å²	23	26.5 Å²	26.5	12%	0.12	15%	0.153	C	C	.	.	I	π-helix	trans	-58.1	-39.9	173.7	-67.4	175.4	0	0	0	112	F24 V25 D26 F32 T33 M291 L294	F24-L28 HydrophobicContact CD1-CD1 4Å; F24-L28 HydrophobicContact CD1-CG 4.16Å; F24-L28 HydrophobicContact CE1-CD1 3.69Å; F24-L28 HydrophobicContact CE1-CD2 3.84Å; F24-L28 HydrophobicContact CE1-CG 3.8Å; F24-L28 HydrophobicContact CE2-CD2 4.42Å; F24-L28 HydrophobicContact CZ-CD1 4.41Å; F24-L28 HydrophobicContact CZ-CD2 3.7Å; F24-L28 HydrophobicContact CZ-CG 4.06Å; F24-L28 PolarHBondContact O-N 3.41Å; V25-L28 WeakPolarHBondContact O-CB 3.35Å; V25-L28 PolarHBondContact O-N 3.1Å; D26-L28 VanDerWaalsContact C-N 3.33Å; D26-L28 PolarHBondContact O-N 2.78Å; L28-F32 HydrophobicContact CD2-CB 4.26Å; L28-F32 HydrophobicContact CD2-CD1 4.4Å; L28-F32 HydrophobicContact CD2-CD2 3.69Å; L28-F32 HydrophobicContact CD2-CE2 4.05Å; L28-F32 HydrophobicContact CD2-CG 3.86Å; L28-F32 HydrophobicContact CG-CD2 4.49Å; L28-F32 WeakPolarHBondContact O-CB 3.49Å; L28-T33 PolarHBondContact O-N 2.03Å; L28-T33 PolarHBondContact O-OG1 3.03Å; L28-M291 HydrophobicContact CB-SD 3.78Å; L28-L294 HydrophobicContact CD1-CD1 4.36Å
29	N	91.4	Very high	84.5	Confident	0 Å²	0	29.8 Å²	29.8	0%	0	16%	0.163	C	C	.	.	I	π-helix	trans	-70.1	-52.6	-178	-77.7	-88.8	0	0	0	113.2	V25 D26 Q27 T33 F202 N206 T295	V25-N29 PolarHBondContact O-N 3.06Å; V25-N29 PolarHBondContact O-ND2 3.02Å; D26-N29 WeakPolarHBondContact O-CB 3.38Å; D26-N29 PolarHBondContact O-N 3Å; Q27-N29 VanDerWaalsContact C-N 3.26Å; Q27-N29 PolarHBondContact O-N 3.49Å; N29-T33 WeakPolarHBondContact O-CB 2.96Å; N29-T33 PolarHBondContact O-OG1 2.87Å; N29-F202 HydrophobicContact CB-CD1 3.63Å; N29-F202 HydrophobicContact CB-CE1 3.72Å; N29-N206 PolarHBondContact OD1-ND2 2.88Å; N29-N206 PolarHBondContact OD1-OD1 3.33Å; N29-N206 VanDerWaalsContact OD1-OD1 3.12Å; N29-T295 WeakPolarHBondContact ND2-CG2 3.31Å; N29-T295 WeakPolarHBondContact OD1-CG2 3.27Å
30	Y	90.2	Very high	86.7	Confident	0 Å²	0	30.8 Å²	30.8	0%	0	17%	0.166	C	C	.	.	I	π-helix	trans	-85.4	-49.6	-177.2	69.2	-94.7	0	0	0	111.5	V15 D26 Q27 S34 A118 W119 H122 F202	V15-Y30 HydrophobicContact CG1-CE2 4.29Å; V15-Y30 HydrophobicContact CG2-CE2 4.15Å; D26-Y30 HydrophobicContact CB-CE1 4.46Å; D26-Y30 WeakPolarHBondContact O-CD1 3.36Å; D26-Y30 VanDerWaalsContact O-CE1 3.3Å; D26-Y30 WeakPolarHBondContact O-CE1 3.48Å; D26-Y30 PolarHBondContact O-N 3.39Å; D26-Y30 VanDerWaalsContact O-N 3.12Å; Q27-Y30 VanDerWaalsContact CA-CE1 3.41Å; Q27-Y30 HydrophobicContact CB-CE1 4.29Å; Q27-Y30 HydrophobicContact CG-CE1 4.24Å; Q27-Y30 WeakPolarHBondContact CG-OH 3.28Å; Y30-S34 WeakPolarHBondContact O-CB 3.44Å; Y30-S34 PolarHBondContact O-N 3.48Å; Y30-S34 PolarHBondContact O-OG 3.01Å; Y30-A118 WeakPolarHBondContact CB-O 3.4Å; Y30-W119 HydrophobicContact CD2-CD2 4.29Å; Y30-W119 HydrophobicContact CD2-CE3 4.24Å; Y30-W119 HydrophobicContact CD2-CH2 4.03Å; Y30-W119 HydrophobicContact CD2-CZ2 4.07Å; Y30-W119 HydrophobicContact CD2-CZ3 4.11Å; Y30-W119 HydrophobicContact CE2-CH2 4.31Å; Y30-W119 HydrophobicContact CE2-CZ3 4.46Å; Y30-W119 PolarHBondContact O-NE1 3.4Å; Y30-H122 HydrophobicContact CD1-CB 3.91Å; Y30-H122 AromaticContact CD1-CG 3.93Å; Y30-H122 AromaticContact CD1-ND1 3.9Å; Y30-H122 AromaticContact CE1-ND1 3.61Å; Y30-H122 HydrophobicContact CG-CB 4.01Å; Y30-H122 AromaticContact CZ-ND1 3.98Å; Y30-F202 HydrophobicContact CD1-CE1 4.41Å; Y30-F202 HydrophobicContact CD1-CZ 4.24Å
31	Q	88.2	Confident	88.4	Confident	41 Å²	41	30.6 Å²	30.6	19%	0.192	17%	0.165	C	C	.	.	I	π-helix	trans	-80	-52.5	-169.9	-173.3	173	0.7	0	0	112.5	Q27 S34 G35	Q27-Q31 WeakPolarHBondContact O-CA 3.35Å; Q27-Q31 VanDerWaalsContact O-CB 3.24Å; Q27-Q31 WeakPolarHBondContact O-CB 2.96Å; Q27-Q31 PolarHBondContact O-N 2.78Å; Q31-S34 PolarHBondContact O-OG 3.01Å; Q31-G35 PolarHBondContact O-N 3.07Å
32	F	90.9	Very high	90.1	Very high	67 Å²	67	34.7 Å²	34.7	29%	0.294	19%	0.19	S	C	.	.	I	π-helix	trans	-72.6	-44.9	-176.2	-72.9	-98	0	0	0	111.3	F24 Q27 L28 S34 G35 I36 W287	F24-F32 HydrophobicContact CE2-CE2 4.18Å; F24-F32 HydrophobicContact CE2-CZ 4.43Å; Q27-F32 PolarHBondContact O-N 3.39Å; L28-F32 HydrophobicContact CD2-CB 4.26Å; L28-F32 HydrophobicContact CD2-CD1 4.4Å; L28-F32 HydrophobicContact CD2-CD2 3.69Å; L28-F32 HydrophobicContact CD2-CE2 4.05Å; L28-F32 HydrophobicContact CD2-CG 3.86Å; L28-F32 HydrophobicContact CG-CD2 4.49Å; L28-F32 WeakPolarHBondContact O-CB 3.49Å; F32-S34 PolarHBondContact O-N 3.38Å; F32-G35 PolarHBondContact O-N 3.39Å; F32-I36 WeakPolarHBondContact O-CB 3.48Å; F32-I36 VanDerWaalsContact O-CG1 3.3Å; F32-I36 WeakPolarHBondContact O-CG1 3.29Å; F32-I36 PolarHBondContact O-N 3.44Å; F32-W287 HydrophobicContact CB-CZ2 4.43Å
33	T	93.5	Very high	91.1	Very high	1 Å²	1	38.8 Å²	38.8	1%	0.006	21%	0.209	C	C	.	.	H	α-helix	trans	-63.4	-43.6	178.8	-52.7	0	0	0	0	111.6	L28 N29 G35 I36 I37 W287 Y288	L28-T33 PolarHBondContact O-N 2.03Å; L28-T33 PolarHBondContact O-OG1 3.03Å; N29-T33 WeakPolarHBondContact O-CB 2.96Å; N29-T33 PolarHBondContact O-OG1 2.87Å; T33-G35 PolarHBondContact O-N 3.24Å; T33-I36 PolarHBondContact O-N 3.39Å; T33-I37 HydrophobicContact CG2-CD1 3.92Å; T33-I37 WeakPolarHBondContact O-CD1 3.09Å; T33-I37 WeakPolarHBondContact O-CG1 3.13Å; T33-I37 PolarHBondContact O-N 3.14Å; T33-W287 PolarHBondContact OG1-NE1 2.95Å; T33-Y288 HydrophobicContact CG2-CE1 3.65Å
34	S	93	Very high	91.5	Very high	13 Å²	13	39 Å²	39	9%	0.091	21%	0.21	C	C	.	.	H	α-helix	trans	-64.7	-39.2	174.4	65.1	0	0	0	0	112.5	Y30 Q31 F32 I37 V38 W119	Y30-S34 WeakPolarHBondContact O-CB 3.44Å; Y30-S34 PolarHBondContact O-N 3.48Å; Y30-S34 PolarHBondContact O-OG 3.01Å; Q31-S34 PolarHBondContact O-OG 3.01Å; F32-S34 PolarHBondContact O-N 3.38Å; S34-I37 PolarHBondContact O-N 2.76Å; S34-V38 WeakPolarHBondContact O-CB 3.4Å; S34-V38 VanDerWaalsContact O-CG2 3.28Å; S34-V38 WeakPolarHBondContact O-CG2 3.31Å; S34-V38 PolarHBondContact O-N 2.74Å; S34-W119 VanDerWaalsContact CB-NE1 3.35Å; S34-W119 PolarHBondContact OG-NE1 2.7Å
35	G	91.7	Very high	91.8	Very high	39 Å²	39	34.4 Å²	34.4	40%	0.402	20%	0.199	S	C	.	.	H	α-helix	trans	-61.6	-43.6	175.6	0	0	0	0	0	113.1	Q31 F32 T33 V38 L39	Q31-G35 PolarHBondContact O-N 3.07Å; F32-G35 PolarHBondContact O-N 3.39Å; T33-G35 PolarHBondContact O-N 3.24Å; G35-V38 PolarHBondContact O-N 2.82Å; G35-L39 WeakPolarHBondContact O-CB 3.09Å; G35-L39 PolarHBondContact O-N 3.15Å
36	I	93.8	Very high	91.8	Very high	33 Å²	33	40.1 Å²	40.1	17%	0.169	22%	0.222	C	C	.	.	H	α-helix	trans	-61	-45.1	174.9	-75.1	169.9	0	0	0	110.8	F32 T33 L39 F40 F283 L284 W287	F32-I36 WeakPolarHBondContact O-CB 3.48Å; F32-I36 VanDerWaalsContact O-CG1 3.3Å; F32-I36 WeakPolarHBondContact O-CG1 3.29Å; F32-I36 PolarHBondContact O-N 3.44Å; T33-I36 PolarHBondContact O-N 3.39Å; I36-L39 WeakPolarHBondContact O-CB 3.38Å; I36-L39 PolarHBondContact O-N 2.86Å; I36-F40 HydrophobicContact CG2-CD2 3.77Å; I36-F40 HydrophobicContact CG2-CE2 3.36Å; I36-F40 HydrophobicContact CG2-CZ 4.34Å; I36-F40 WeakPolarHBondContact O-CD2 3.35Å; I36-F40 PolarHBondContact O-N 2.04Å; I36-F283 HydrophobicContact CG2-CE1 3.79Å; I36-L284 HydrophobicContact CG2-CD2 4.21Å; I36-W287 HydrophobicContact CD1-CD2 4.01Å; I36-W287 HydrophobicContact CD1-CE3 4.19Å; I36-W287 HydrophobicContact CD1-CH2 3.64Å; I36-W287 HydrophobicContact CD1-CZ2 3.43Å; I36-W287 VanDerWaalsContact CD1-CZ2 3.43Å; I36-W287 HydrophobicContact CD1-CZ3 4.01Å
37	I	95.2	Very high	91.7	Very high	0 Å²	0	43.3 Å²	43.3	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-65.5	-43.7	179.1	-65.7	163.6	0	0	0	111.2	T33 S34 L39 F40 I41 L111 Q114 A115 L284 Y288	T33-I37 HydrophobicContact CG2-CD1 3.92Å; T33-I37 WeakPolarHBondContact O-CD1 3.09Å; T33-I37 WeakPolarHBondContact O-CG1 3.13Å; T33-I37 PolarHBondContact O-N 3.14Å; S34-I37 PolarHBondContact O-N 2.76Å; I37-L39 VanDerWaalsContact C-N 3.27Å; I37-L39 PolarHBondContact O-N 2.75Å; I37-F40 PolarHBondContact O-N 3.34Å; I37-F40 VanDerWaalsContact O-N 3.11Å; I37-I41 HydrophobicContact CG2-CD1 3.94Å; I37-I41 HydrophobicContact CG2-CG1 4.38Å; I37-I41 WeakPolarHBondContact O-CG1 3.38Å; I37-I41 PolarHBondContact O-N 3.32Å; I37-L111 HydrophobicContact CG2-CB 3.8Å; I37-L111 HydrophobicContact CG2-CD2 4.23Å; I37-L111 WeakPolarHBondContact CG2-O 3.12Å; I37-Q114 HydrophobicContact CD1-CB 4.34Å; I37-A115 HydrophobicContact CB-CB 4.14Å; I37-A115 HydrophobicContact CD1-CB 4.27Å; I37-A115 HydrophobicContact CG2-CB 3.88Å; I37-L284 HydrophobicContact CG1-CD2 4.15Å; I37-Y288 VanDerWaalsContact CD1-OH 3.29Å; I37-Y288 WeakPolarHBondContact CD1-OH 3.49Å
38	V	94.2	Very high	91.6	Very high	78 Å²	78	45.5 Å²	45.5	47%	0.473	24%	0.243	S	C	.	.	H	α-helix	trans	-59.5	-41	175.8	169.5	0	0	0	0	110.8	S34 G35 F40 I41 V42	S34-V38 WeakPolarHBondContact O-CB 3.4Å; S34-V38 VanDerWaalsContact O-CG2 3.28Å; S34-V38 WeakPolarHBondContact O-CG2 3.31Å; S34-V38 PolarHBondContact O-N 2.74Å; G35-V38 PolarHBondContact O-N 2.82Å; V38-F40 PolarHBondContact O-N 2.92Å; V38-I41 PolarHBondContact O-N 3.32Å; V38-V42 WeakPolarHBondContact O-CG2 3.38Å; V38-V42 PolarHBondContact O-N 3.23Å
39	L	93.9	Very high	91.3	Very high	101 Å²	101	54.3 Å²	54.3	53%	0.529	28%	0.276	S	S	.	.	H	α-helix	trans	-59.5	-46	173.6	179.3	66.4	0	0	0	111.6	G35 I36 I37 I41 V42 M43	G35-L39 WeakPolarHBondContact O-CB 3.09Å; G35-L39 PolarHBondContact O-N 3.15Å; I36-L39 WeakPolarHBondContact O-CB 3.38Å; I36-L39 PolarHBondContact O-N 2.86Å; I37-L39 VanDerWaalsContact C-N 3.27Å; I37-L39 PolarHBondContact O-N 2.75Å; L39-I41 PolarHBondContact O-N 3.14Å; L39-V42 PolarHBondContact O-N 3.41Å; L39-M43 HydrophobicContact CG-CE 4.25Å; L39-M43 WeakPolarHBondContact O-CG 3.23Å; L39-M43 PolarHBondContact O-N 2.95Å
40	F	94.5	Very high	91.1	Very high	25 Å²	25	59 Å²	59	11%	0.11	30%	0.304	C	S	.	.	H	α-helix	trans	-62.5	-39.7	176	-72.8	-54.2	0	0	0	113.3	I36 I37 V38 V42 M43 I44 V280 F283 L284	I36-F40 HydrophobicContact CG2-CD2 3.77Å; I36-F40 HydrophobicContact CG2-CE2 3.36Å; I36-F40 HydrophobicContact CG2-CZ 4.34Å; I36-F40 WeakPolarHBondContact O-CD2 3.35Å; I36-F40 PolarHBondContact O-N 2.04Å; I37-F40 PolarHBondContact O-N 3.34Å; I37-F40 VanDerWaalsContact O-N 3.11Å; V38-F40 PolarHBondContact O-N 2.92Å; F40-V42 VanDerWaalsContact C-N 3.35Å; F40-V42 PolarHBondContact O-N 3.45Å; F40-M43 HydrophobicContact CD1-CE 3.15Å; F40-M43 HydrophobicContact CE1-CE 3.5Å; F40-M43 HydrophobicContact CG-CE 4.15Å; F40-M43 PolarHBondContact O-N 3.13Å; F40-I44 VanDerWaalsContact O-CG1 3.29Å; F40-I44 WeakPolarHBondContact O-CG1 3.49Å; F40-I44 PolarHBondContact O-N 2.91Å; F40-V280 HydrophobicContact CB-CG1 3.96Å; F40-V280 HydrophobicContact CB-CG2 4.47Å; F40-V280 HydrophobicContact CD1-CB 4.26Å; F40-V280 HydrophobicContact CD1-CG1 3.92Å; F40-V280 HydrophobicContact CD1-CG2 3.49Å; F40-V280 VanDerWaalsContact CD1-CG2 3.49Å; F40-V280 HydrophobicContact CD2-CG1 3.97Å; F40-V280 HydrophobicContact CE1-CG1 4.45Å; F40-V280 HydrophobicContact CE1-CG2 3.93Å; F40-V280 HydrophobicContact CE2-CG1 4.45Å; F40-V280 HydrophobicContact CG-CG1 3.7Å; F40-V280 HydrophobicContact CG-CG2 4.11Å; F40-F283 AromaticContact CE2-CD1 3.41Å; F40-F283 HydrophobicContact CE2-CD1 3.41Å; F40-F283 VanDerWaalsContact CE2-CD1 3.41Å; F40-F283 AromaticContact CE2-CE1 3.65Å; F40-F283 HydrophobicContact CE2-CE1 3.65Å; F40-F283 HydrophobicContact CE2-CG 4.41Å; F40-F283 HydrophobicContact CZ-CB 4.45Å; F40-F283 AromaticContact CZ-CD1 3.35Å; F40-F283 HydrophobicContact CZ-CD1 3.35Å; F40-F283 AromaticContact CZ-CE1 3.71Å; F40-F283 HydrophobicContact CZ-CE1 3.71Å; F40-F283 AromaticContact CZ-CG 3.95Å; F40-F283 HydrophobicContact CZ-CG 3.95Å; F40-L284 HydrophobicContact CD2-CD1 4.47Å; F40-L284 HydrophobicContact CD2-CD2 4.07Å; F40-L284 HydrophobicContact CD2-CG 4.27Å; F40-L284 HydrophobicContact CE2-CD2 3.94Å; F40-L284 HydrophobicContact CE2-CG 4.17Å
41	I	94.2	Very high	90.8	Very high	39 Å²	39	60.2 Å²	60.2	20%	0.2	32%	0.318	C	S	.	.	H	α-helix	trans	-60.6	-45.8	175.2	-67.4	165	0	0	0	110.4	I37 V38 L39 M43 I44 G45 A108 L111 A112	I37-I41 HydrophobicContact CG2-CD1 3.94Å; I37-I41 HydrophobicContact CG2-CG1 4.38Å; I37-I41 WeakPolarHBondContact O-CG1 3.38Å; I37-I41 PolarHBondContact O-N 3.32Å; V38-I41 PolarHBondContact O-N 3.32Å; L39-I41 PolarHBondContact O-N 3.14Å; I41-M43 PolarHBondContact O-N 3.38Å; I41-I44 PolarHBondContact O-N 3.17Å; I41-G45 PolarHBondContact O-N 3.06Å; I41-A108 HydrophobicContact CG2-CB 4.47Å; I41-L111 HydrophobicContact CD1-CB 3.87Å; I41-L111 HydrophobicContact CG1-CB 3.67Å; I41-L111 HydrophobicContact CG1-CD1 4.21Å; I41-A112 HydrophobicContact CD1-CB 4.01Å
42	V	93.1	Very high	90.7	Very high	92 Å²	92	62 Å²	62	56%	0.558	33%	0.325	S	S	*	.	H	α-helix	trans	-62.6	-42.5	177.5	172.4	0	0	0	0	111	V38 L39 F40 G45 F46	V38-V42 WeakPolarHBondContact O-CG2 3.38Å; V38-V42 PolarHBondContact O-N 3.23Å; L39-V42 PolarHBondContact O-N 3.41Å; F40-V42 VanDerWaalsContact C-N 3.35Å; F40-V42 PolarHBondContact O-N 3.45Å; V42-G45 PolarHBondContact O-N 3.28Å; V42-F46 VanDerWaalsContact O-CB 3.32Å; V42-F46 WeakPolarHBondContact O-CB 3.24Å; V42-F46 PolarHBondContact O-N 3.04Å
43	M	90.7	Very high	90.5	Very high	89 Å²	89	60 Å²	60	44%	0.438	32%	0.319	S	S	.	.	H	α-helix	trans	-64.7	-44.2	178	-70.7	-169.4	-58.2	0	0	112.6	L39 F40 I41 F46 R47	L39-M43 HydrophobicContact CG-CE 4.25Å; L39-M43 WeakPolarHBondContact O-CG 3.23Å; L39-M43 PolarHBondContact O-N 2.95Å; F40-M43 HydrophobicContact CD1-CE 3.15Å; F40-M43 HydrophobicContact CE1-CE 3.5Å; F40-M43 HydrophobicContact CG-CE 4.15Å; F40-M43 PolarHBondContact O-N 3.13Å; I41-M43 PolarHBondContact O-N 3.38Å; M43-F46 PolarHBondContact O-N 3.34Å; M43-R47 PolarHBondContact O-N 3.04Å; M43-R47 VanDerWaalsContact O-N 3.11Å
44	I	91.1	Very high	90.4	Very high	8 Å²	8	60 Å²	60	4%	0.041	32%	0.319	C	S	.	.	H	α-helix	trans	-63.2	-46.1	175.9	-67.6	167.1	0	0	0	110.1	F40 I41 F46 R47 Q48 V107 L111	F40-I44 VanDerWaalsContact O-CG1 3.29Å; F40-I44 WeakPolarHBondContact O-CG1 3.49Å; F40-I44 PolarHBondContact O-N 2.91Å; I41-I44 PolarHBondContact O-N 3.17Å; I44-F46 PolarHBondContact O-N 3.05Å; I44-R47 PolarHBondContact O-N 3.14Å; I44-Q48 WeakPolarHBondContact O-CG 3.38Å; I44-Q48 PolarHBondContact O-N 2.98Å; I44-V107 HydrophobicContact CD1-CG1 4.41Å; I44-V107 HydrophobicContact CG2-CG1 4.24Å; I44-L111 HydrophobicContact CD1-CD1 3.86Å
45	G	90.9	Very high	90.4	Very high	29 Å²	29	63.6 Å²	63.6	30%	0.299	33%	0.334	S	S	.	.	H	α-helix	trans	-62.6	-41.2	178.8	0	0	0	0	0	112.9	I41 V42 R47 Q48 Y49	I41-G45 PolarHBondContact O-N 3.06Å; V42-G45 PolarHBondContact O-N 3.28Å; G45-R47 VanDerWaalsContact C-N 3.35Å; G45-R47 PolarHBondContact O-N 3.35Å; G45-Q48 PolarHBondContact O-N 2.93Å; G45-Y49 WeakPolarHBondContact O-CB 3.24Å; G45-Y49 PolarHBondContact O-N 3.4Å
46	F	90.6	Very high	90.6	Very high	142 Å²	142	62.5 Å²	62.5	62%	0.623	32%	0.32	S	S	*	.	H	α-helix	trans	-60.8	-44.2	174.9	-178.7	-98.9	0	0	0	111.6	V42 M43 I44 Q48 Y49 V50	V42-F46 VanDerWaalsContact O-CB 3.32Å; V42-F46 WeakPolarHBondContact O-CB 3.24Å; V42-F46 PolarHBondContact O-N 3.04Å; M43-F46 PolarHBondContact O-N 3.34Å; I44-F46 PolarHBondContact O-N 3.05Å; F46-Q48 VanDerWaalsContact C-N 3.3Å; F46-Q48 PolarHBondContact O-N 3.31Å; F46-Y49 PolarHBondContact O-N 3.17Å; F46-V50 HydrophobicContact CD1-CG2 4.39Å; F46-V50 HydrophobicContact CD2-CG2 3.91Å; F46-V50 HydrophobicContact CE1-CG2 4.06Å; F46-V50 HydrophobicContact CE2-CG2 3.54Å; F46-V50 HydrophobicContact CG-CG2 4.32Å; F46-V50 HydrophobicContact CZ-CG2 3.63Å; F46-V50 PolarHBondContact O-N 2.85Å
47	R	86.2	Confident	90.6	Very high	77 Å²	77	70.1 Å²	70.1	29%	0.291	35%	0.347	S	S	.	.	H	α-helix	trans	-64.2	-34.4	177.7	-176.6	61.9	-177.8	92.3	-4.7	112.8	M43 I44 G45 F276	M43-R47 PolarHBondContact O-N 3.04Å; M43-R47 VanDerWaalsContact O-N 3.11Å; I44-R47 PolarHBondContact O-N 3.14Å; G45-R47 VanDerWaalsContact C-N 3.35Å; G45-R47 PolarHBondContact O-N 3.35Å; R47-F276 HydrophobicContact CG-CD2 4Å; R47-F276 HydrophobicContact CG-CE2 3.86Å
48	Q	86.4	Confident	90.6	Very high	59 Å²	59	71 Å²	71	28%	0.276	35%	0.352	S	S	.	.	H	α-helix	trans	-75	-28.4	176.6	-72.2	176.8	-4.7	0	0	113.2	I44 G45 F46 G51 V273	I44-Q48 WeakPolarHBondContact O-CG 3.38Å; I44-Q48 PolarHBondContact O-N 2.98Å; G45-Q48 PolarHBondContact O-N 2.93Å; F46-Q48 VanDerWaalsContact C-N 3.3Å; F46-Q48 PolarHBondContact O-N 3.31Å; Q48-G51 VanDerWaalsContact O-O 3.11Å; Q48-V273 HydrophobicContact CG-CG2 4.12Å
49	Y	84.3	Confident	90.5	Very high	208 Å²	208	69.1 Å²	69.1	82%	0.816	34%	0.341	S	S	*	.	H	α-helix	trans	-87	-42.1	-178.5	-175.5	-95.5	0	0	0	113.2	G45 F46	G45-Y49 WeakPolarHBondContact O-CB 3.24Å; G45-Y49 PolarHBondContact O-N 3.4Å; F46-Y49 PolarHBondContact O-N 3.17Å
50	V	86.3	Confident	90.3	Very high	97 Å²	97	73.9 Å²	73.9	59%	0.588	36%	0.361	S	S	*	.	H	α-helix	trans	-77.5	-22.3	-174.7	174.3	0	0	0	0	112.7	F46	F46-V50 HydrophobicContact CD1-CG2 4.39Å; F46-V50 HydrophobicContact CD2-CG2 3.91Å; F46-V50 HydrophobicContact CE1-CG2 4.06Å; F46-V50 HydrophobicContact CE2-CG2 3.54Å; F46-V50 HydrophobicContact CG-CG2 4.32Å; F46-V50 HydrophobicContact CZ-CG2 3.63Å; F46-V50 PolarHBondContact O-N 2.85Å
51	G	83.2	Confident	90.1	Very high	27 Å²	27	79.9 Å²	79.9	28%	0.278	39%	0.389	S	S	.	.	S	Bend	trans	-140.2	166.5	179.3	0	0	0	0	0	112.3	Q48	Q48-G51 VanDerWaalsContact O-O 3.11Å
52	K	86.4	Confident	89.9	Confident	77 Å²	77	78.8 Å²	78.8	34%	0.335	38%	0.383	S	S	.	.			trans	-62	134.1	173.4	-63.6	-175.1	171.1	-170.8	0	109.7	L54 D68 E71	K52-L54 VanDerWaalsContact C-N 3.26Å; K52-L54 PolarHBondContact O-N 2.7Å; K52-D68 WeakPolarHBondContact CE-OD1 3.09Å; K52-D68 IonicContact NZ-OD1 2.62Å; K52-D68 PolarHBondContact NZ-OD1 3.48Å; K52-E71 WeakPolarHBondContact CD-OE2 3.3Å; K52-E71 WeakPolarHBondContact CE-OE2 3.18Å; K52-E71 IonicContact NZ-OE2 3.08Å; K52-E71 PolarHBondContact NZ-OE2 2.61Å
53	P	86.7	Confident	89.9	Confident	26 Å²	26	78 Å²	78	17%	0.169	38%	0.379	C	S	.	.	S	Bend	trans	-73.5	-21	-176.2	30.8	-36.9	0	0	0	113	W75 V273	P53-W75 HydrophobicContact CB-CD2 4.06Å; P53-W75 HydrophobicContact CB-CE3 3.76Å; P53-W75 HydrophobicContact CB-CH2 3.68Å; P53-W75 HydrophobicContact CB-CZ2 4Å; P53-W75 HydrophobicContact CB-CZ3 3.56Å; P53-W75 HydrophobicContact CG-CD2 3.74Å; P53-W75 HydrophobicContact CG-CE3 3.81Å; P53-W75 HydrophobicContact CG-CG 4.17Å; P53-W75 HydrophobicContact CG-CH2 4.41Å; P53-W75 HydrophobicContact CG-CZ2 4.38Å; P53-W75 HydrophobicContact CG-CZ3 4.15Å; P53-V273 HydrophobicContact CB-CG2 4Å; P53-V273 WeakPolarHBondContact O-CG2 3.31Å
54	L	91.7	Very high	89.9	Confident	2 Å²	2	77.7 Å²	77.7	1%	0.01	39%	0.385	C	S	.	.			trans	-146	147.9	-178.5	-177.5	93.3	0	0	0	108.2	K52 C56 C74 W75 C269 V270 L271	K52-L54 VanDerWaalsContact C-N 3.26Å; K52-L54 PolarHBondContact O-N 2.7Å; L54-C56 WeakPolarHBondContact CD2-SG 3.47Å; L54-C74 HydrophobicContact CD2-CB 3.9Å; L54-W75 HydrophobicContact CB-CE3 4.26Å; L54-C269 HydrophobicContact CD1-CB 3.67Å; L54-C269 HydrophobicContact CD2-CB 3.65Å; L54-C269 HydrophobicContact CG-CB 3.73Å; L54-V270 WeakPolarHBondContact CA-O 3.31Å; L54-V270 VanDerWaalsContact CD1-O 3.23Å; L54-V270 WeakPolarHBondContact CD1-O 3.3Å; L54-L271 HydrophobicContact CB-CD1 4.41Å; L54-L271 HydrophobicContact CD1-CB 3.84Å; L54-L271 HydrophobicContact CD1-CD1 3.53Å; L54-L271 HydrophobicContact CD1-CG 4.24Å
55	H	93.2	Very high	90	Very high	88 Å²	88	81 Å²	81	41%	0.407	41%	0.409	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-125	131.8	170.9	-73.2	-78.4	0	0	0	109.9	E71 C269 V270	H55-E71 WeakPolarHBondContact CA-OE1 3.34Å; H55-E71 IonicContact ND1-OE1 3.25Å; H55-C269 CarbonylContact O-C 3.58Å; H55-C269 VanDerWaalsContact O-CA 3.23Å; H55-C269 WeakPolarHBondContact O-CA 3.29Å; H55-V270 PolarHBondContact N-O 3.47Å; H55-V270 PolarHBondContact O-N 3.15Å
56	C	95.4	Very high	90.1	Very high	16 Å²	16	84.8 Å²	84.8	11%	0.108	41%	0.414	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.2	141	-177.8	-65.1	0	0	0	0	112.2	L54 V58 E71 L267 C269	L54-C56 WeakPolarHBondContact CD2-SG 3.47Å; C56-V58 HydrophobicContact CB-CG1 4.41Å; C56-V58 PolarHBondContact O-N 2.92Å; C56-E71 HydrophobicContact CB-CG 3.99Å; C56-E71 PolarHBondContact N-OE1 3.42Å; C56-E71 VanDerWaalsContact N-OE1 3.14Å; C56-L267 HydrophobicContact CB-CB 4.33Å; C56-L267 HydrophobicContact CB-CD1 4.4Å; C56-C269 HydrophobicContact CB-CB 4.05Å; C56-C269 WeakPolarHBondContact CB-SG 3.03Å; C56-C269 WeakPolarHBondContact SG-CB 3.36Å; C56-C269 CovalentContact SG-SG 2.04Å; C56-C269 PolarHBondContact SG-SG 2.89Å
57	W	94.8	Very high	90.2	Very high	193 Å²	193	81 Å²	81	73%	0.731	40%	0.399	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-77	105.7	165.3	-175.2	8	0	0	0	108.7	Q268	W57-Q268 PolarHBondContact N-O 2.92Å
58	V	93.9	Very high	90.6	Very high	18 Å²	18	80.7 Å²	80.7	11%	0.109	40%	0.402	C	S	.	.			trans	-99.8	154.8	177.8	-66.6	0	0	0	0	112.1	C56 F62 E67 A70 L267	C56-V58 HydrophobicContact CB-CG1 4.41Å; C56-V58 PolarHBondContact O-N 2.92Å; V58-F62 HydrophobicContact CB-CB 4.33Å; V58-F62 HydrophobicContact CB-CD2 4.05Å; V58-F62 HydrophobicContact CB-CG 4.36Å; V58-F62 HydrophobicContact CG1-CD2 4.09Å; V58-F62 HydrophobicContact CG2-CB 4.35Å; V58-E67 HydrophobicContact CB-CG 4.42Å; V58-E67 HydrophobicContact CG1-CG 4.46Å; V58-E67 HydrophobicContact CG2-CB 4.38Å; V58-E67 HydrophobicContact CG2-CG 3.52Å; V58-E67 WeakPolarHBondContact CG2-OE1 3.27Å; V58-A70 HydrophobicContact CG1-CB 4.48Å; V58-L267 HydrophobicContact CG1-CD1 4.16Å; V58-L267 HydrophobicContact CG1-CD2 4.25Å
59	P	92.2	Very high	90.8	Very high	38 Å²	38	84.3 Å²	84.3	25%	0.247	42%	0.415	C	S	.	.			trans	-60	151	170	-22.3	33.9	0	0	0	112.3	E61 F62 Y265	P59-E61 WeakPolarHBondContact CB-OE2 3.09Å; P59-E61 PolarHBondContact O-N 3.43Å; P59-E61 VanDerWaalsContact O-N 3.1Å; P59-F62 HydrophobicContact CB-CD1 4.43Å; P59-F62 HydrophobicContact CG-CE1 4.33Å; P59-F62 PolarHBondContact O-N 2.92Å; P59-F62 VanDerWaalsContact O-N 3.12Å; P59-Y265 HydrophobicContact CG-CD1 4.07Å; P59-Y265 HydrophobicContact CG-CE1 4.43Å
60	Q	90.7	Very high	91.3	Very high	201 Å²	201	74.4 Å²	74.4	94%	0.939	38%	0.376	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.2	-15.7	-178.7	-69.2	-173.7	-27.4	0	0	113.9	F62	Q60-F62 PolarHBondContact O-N 3.45Å
61	E	89.3	Confident	91.7	Very high	151 Å²	151	70.7 Å²	70.7	71%	0.706	35%	0.352	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.4	-12.7	176.7	-50.1	91.6	-168.1	0	0	113.4	P59	P59-E61 WeakPolarHBondContact CB-OE2 3.09Å; P59-E61 PolarHBondContact O-N 3.43Å; P59-E61 VanDerWaalsContact O-N 3.1Å
62	F	90.1	Very high	92.1	Very high	17 Å²	17	74.1 Å²	74.1	8%	0.075	36%	0.364	C	S	.	.			trans	-79.1	128.1	-177.2	-79.7	31.9	0	0	0	109.9	V58 P59 Q60 W66 E67 A70 Y265	V58-F62 HydrophobicContact CB-CB 4.33Å; V58-F62 HydrophobicContact CB-CD2 4.05Å; V58-F62 HydrophobicContact CB-CG 4.36Å; V58-F62 HydrophobicContact CG1-CD2 4.09Å; V58-F62 HydrophobicContact CG2-CB 4.35Å; P59-F62 HydrophobicContact CB-CD1 4.43Å; P59-F62 HydrophobicContact CG-CE1 4.33Å; P59-F62 PolarHBondContact O-N 2.92Å; P59-F62 VanDerWaalsContact O-N 3.12Å; Q60-F62 PolarHBondContact O-N 3.45Å; F62-W66 HydrophobicContact CB-CB 4.08Å; F62-W66 HydrophobicContact CD2-CB 3.99Å; F62-W66 HydrophobicContact CE1-CE3 4.46Å; F62-W66 HydrophobicContact CG-CB 4.12Å; F62-E67 HydrophobicContact CB-CG 4.15Å; F62-A70 HydrophobicContact CE2-CB 4.31Å; F62-Y265 HydrophobicContact CE1-CD1 4.34Å; F62-Y265 HydrophobicContact CE1-CE1 4.09Å; F62-Y265 HydrophobicContact CE1-CE2 4.29Å; F62-Y265 HydrophobicContact CZ-CD1 4.26Å; F62-Y265 AromaticContact CZ-CD2 3.98Å; F62-Y265 HydrophobicContact CZ-CD2 3.98Å; F62-Y265 HydrophobicContact CZ-CE1 4.38Å; F62-Y265 HydrophobicContact CZ-CE2 4.12Å; F62-Y265 HydrophobicContact CZ-CG 4.05Å
63	T	92.9	Very high	92.4	Very high	76 Å²	76	72 Å²	72	47%	0.466	36%	0.356	S	S	.	.			trans	-75.5	159.4	169	61.3	0	0	0	0	109.8	S65 W66 E67	T63-S65 PolarHBondContact O-N 3.04Å; T63-S65 PolarHBondContact OG1-OG 3.18Å; T63-W66 WeakPolarHBondContact O-CA 3.37Å; T63-W66 WeakPolarHBondContact O-CB 3.5Å; T63-W66 PolarHBondContact O-N 2.87Å; T63-E67 PolarHBondContact O-N 2.79Å
64	S	92.3	Very high	92.8	Very high	82 Å²	82	70.8 Å²	70.8	57%	0.573	35%	0.348	S	S	*	.	H	α-helix	trans	-53	-33.3	-178.8	-50.2	0	0	0	0	114.3	E67 D68	S64-E67 WeakPolarHBondContact O-CB 3.44Å; S64-E67 PolarHBondContact O-N 2.99Å; S64-D68 PolarHBondContact O-N 3.17Å
65	S	92.9	Very high	92.8	Very high	78 Å²	78	72.9 Å²	72.9	55%	0.545	36%	0.356	S	S	.	.	H	α-helix	trans	-67.3	-31.7	173.5	52.8	0	0	0	0	114.2	T63 Y69	T63-S65 PolarHBondContact O-N 3.04Å; T63-S65 PolarHBondContact OG1-OG 3.18Å; S65-Y69 WeakPolarHBondContact O-CB 3.43Å; S65-Y69 PolarHBondContact O-N 3.4Å; S65-Y69 VanDerWaalsContact O-N 3.1Å
66	W	92.4	Very high	92.7	Very high	107 Å²	107	73.7 Å²	73.7	41%	0.405	37%	0.367	S	S	.	.	H	α-helix	trans	-77.1	-34.8	175.3	-72	48.9	0	0	0	110.7	F62 T63 Y69 A70	F62-W66 HydrophobicContact CB-CB 4.08Å; F62-W66 HydrophobicContact CD2-CB 3.99Å; F62-W66 HydrophobicContact CE1-CE3 4.46Å; F62-W66 HydrophobicContact CG-CB 4.12Å; T63-W66 WeakPolarHBondContact O-CA 3.37Å; T63-W66 WeakPolarHBondContact O-CB 3.5Å; T63-W66 PolarHBondContact O-N 2.87Å; W66-Y69 PolarHBondContact O-N 3.33Å; W66-A70 VanDerWaalsContact O-CB 3.31Å; W66-A70 WeakPolarHBondContact O-CB 3.3Å; W66-A70 PolarHBondContact O-N 3.1Å
67	E	93.7	Very high	92.3	Very high	64 Å²	64	78.6 Å²	78.6	30%	0.299	39%	0.388	S	S	.	.	H	α-helix	trans	-60.1	-51.3	170.9	-55.7	-177.6	159.1	0	0	110.6	V58 F62 T63 S64 Y69 A70 E71	V58-E67 HydrophobicContact CB-CG 4.42Å; V58-E67 HydrophobicContact CG1-CG 4.46Å; V58-E67 HydrophobicContact CG2-CB 4.38Å; V58-E67 HydrophobicContact CG2-CG 3.52Å; V58-E67 WeakPolarHBondContact CG2-OE1 3.27Å; F62-E67 HydrophobicContact CB-CG 4.15Å; T63-E67 PolarHBondContact O-N 2.79Å; S64-E67 WeakPolarHBondContact O-CB 3.44Å; S64-E67 PolarHBondContact O-N 2.99Å; E67-Y69 VanDerWaalsContact C-N 3.28Å; E67-Y69 PolarHBondContact O-N 2.89Å; E67-A70 PolarHBondContact O-N 3.49Å; E67-E71 WeakPolarHBondContact O-CB 3.38Å; E67-E71 WeakPolarHBondContact O-CG 3.49Å; E67-E71 PolarHBondContact O-N 3.1Å
68	D	93	Very high	92	Very high	69 Å²	69	71.8 Å²	71.8	37%	0.369	37%	0.366	S	S	.	.	H	α-helix	trans	-58.4	-40.6	176.5	-73.1	-23.5	0	0	0	111.8	K52 S64 N72	K52-D68 WeakPolarHBondContact CE-OD1 3.09Å; K52-D68 IonicContact NZ-OD1 2.62Å; K52-D68 PolarHBondContact NZ-OD1 3.48Å; S64-D68 PolarHBondContact O-N 3.17Å; D68-N72 VanDerWaalsContact O-CB 3.3Å; D68-N72 WeakPolarHBondContact O-CB 3.4Å; D68-N72 VanDerWaalsContact O-CG 3.24Å; D68-N72 PolarHBondContact O-N 2.85Å; D68-N72 PolarHBondContact O-ND2 3.46Å
69	Y	92.5	Very high	91.9	Very high	136 Å²	136	70.9 Å²	70.9	53%	0.533	36%	0.361	S	S	.	.	H	α-helix	trans	-64.6	-46.4	176.3	175.6	-106.1	0	0	0	112	S65 W66 E67 N72 I73	S65-Y69 WeakPolarHBondContact O-CB 3.43Å; S65-Y69 PolarHBondContact O-N 3.4Å; S65-Y69 VanDerWaalsContact O-N 3.1Å; W66-Y69 PolarHBondContact O-N 3.33Å; E67-Y69 VanDerWaalsContact C-N 3.28Å; E67-Y69 PolarHBondContact O-N 2.89Å; Y69-N72 PolarHBondContact O-N 3.43Å; Y69-I73 HydrophobicContact CD1-CD1 3.95Å; Y69-I73 HydrophobicContact CD2-CD1 4.16Å; Y69-I73 HydrophobicContact CE1-CD1 3.32Å; Y69-I73 HydrophobicContact CE1-CG1 4.46Å; Y69-I73 HydrophobicContact CE2-CD1 3.55Å; Y69-I73 HydrophobicContact CE2-CG1 4.19Å; Y69-I73 HydrophobicContact CG-CD1 4.35Å; Y69-I73 WeakPolarHBondContact O-CB 3.46Å; Y69-I73 WeakPolarHBondContact O-CG1 3.37Å; Y69-I73 PolarHBondContact O-N 3.03Å; Y69-I73 VanDerWaalsContact OH-CD1 3.27Å; Y69-I73 WeakPolarHBondContact OH-CD1 3.47Å
70	A	93.8	Very high	91.9	Very high	0 Å²	0	69.2 Å²	69.2	0%	0	35%	0.349	C	S	.	.	H	α-helix	trans	-63	-46.7	179.1	0	0	0	0	0	111.6	V58 F62 W66 E67 N72 I73 C74 V252 L267	V58-A70 HydrophobicContact CG1-CB 4.48Å; F62-A70 HydrophobicContact CE2-CB 4.31Å; W66-A70 VanDerWaalsContact O-CB 3.31Å; W66-A70 WeakPolarHBondContact O-CB 3.3Å; W66-A70 PolarHBondContact O-N 3.1Å; E67-A70 PolarHBondContact O-N 3.49Å; A70-N72 PolarHBondContact O-N 3.42Å; A70-I73 PolarHBondContact O-N 2.72Å; A70-C74 WeakPolarHBondContact O-CB 3.18Å; A70-C74 PolarHBondContact O-N 3.45Å; A70-C74 PolarHBondContact O-SG 2.91Å; A70-V252 HydrophobicContact CB-CG2 4.32Å; A70-L267 HydrophobicContact CB-CD1 3.72Å
71	E	94	Very high	91.9	Very high	19 Å²	19	60.4 Å²	60.4	9%	0.089	31%	0.308	C	S	.	.	H	α-helix	trans	-60.3	-43.6	176.6	-72.4	178.9	157.5	0	0	111.8	K52 H55 C56 E67 C74 W75	K52-E71 WeakPolarHBondContact CD-OE2 3.3Å; K52-E71 WeakPolarHBondContact CE-OE2 3.18Å; K52-E71 IonicContact NZ-OE2 3.08Å; K52-E71 PolarHBondContact NZ-OE2 2.61Å; H55-E71 WeakPolarHBondContact CA-OE1 3.34Å; H55-E71 IonicContact ND1-OE1 3.25Å; C56-E71 HydrophobicContact CB-CG 3.99Å; C56-E71 PolarHBondContact N-OE1 3.42Å; C56-E71 VanDerWaalsContact N-OE1 3.14Å; E67-E71 WeakPolarHBondContact O-CB 3.38Å; E67-E71 WeakPolarHBondContact O-CG 3.49Å; E67-E71 PolarHBondContact O-N 3.1Å; E71-C74 PolarHBondContact O-N 3.2Å; E71-W75 WeakPolarHBondContact O-CB 3.23Å; E71-W75 PolarHBondContact O-N 3.37Å
72	N	92.8	Very high	91.8	Very high	98 Å²	98	53.8 Å²	53.8	52%	0.524	28%	0.277	S	S	.	.	H	α-helix	trans	-66.5	-39.8	177.7	-78	-47.6	0	0	0	112.6	D68 Y69 A70 W75 V76	D68-N72 VanDerWaalsContact O-CB 3.3Å; D68-N72 WeakPolarHBondContact O-CB 3.4Å; D68-N72 VanDerWaalsContact O-CG 3.24Å; D68-N72 PolarHBondContact O-N 2.85Å; D68-N72 PolarHBondContact O-ND2 3.46Å; Y69-N72 PolarHBondContact O-N 3.43Å; A70-N72 PolarHBondContact O-N 3.42Å; N72-W75 PolarHBondContact O-N 3.19Å; N72-V76 WeakPolarHBondContact O-CG2 3.39Å; N72-V76 PolarHBondContact O-N 3.29Å; N72-V76 VanDerWaalsContact O-N 3.15Å
73	I	93	Very high	91.6	Very high	33 Å²	33	56.3 Å²	56.3	17%	0.169	29%	0.291	C	S	.	.	H	α-helix	trans	-63	-47.9	174.8	-79.3	-176.3	0	0	0	110.8	Y69 A70 W75 V76 Q77 V252	Y69-I73 HydrophobicContact CD1-CD1 3.95Å; Y69-I73 HydrophobicContact CD2-CD1 4.16Å; Y69-I73 HydrophobicContact CE1-CD1 3.32Å; Y69-I73 HydrophobicContact CE1-CG1 4.46Å; Y69-I73 HydrophobicContact CE2-CD1 3.55Å; Y69-I73 HydrophobicContact CE2-CG1 4.19Å; Y69-I73 HydrophobicContact CG-CD1 4.35Å; Y69-I73 WeakPolarHBondContact O-CB 3.46Å; Y69-I73 WeakPolarHBondContact O-CG1 3.37Å; Y69-I73 PolarHBondContact O-N 3.03Å; Y69-I73 VanDerWaalsContact OH-CD1 3.27Å; Y69-I73 WeakPolarHBondContact OH-CD1 3.47Å; A70-I73 PolarHBondContact O-N 2.72Å; I73-W75 PolarHBondContact O-N 2.63Å; I73-V76 PolarHBondContact O-N 3.09Å; I73-Q77 HydrophobicContact CG2-CG 4.19Å; I73-Q77 WeakPolarHBondContact O-CB 3.34Å; I73-Q77 PolarHBondContact O-N 3.14Å; I73-V252 HydrophobicContact CG2-CG2 4.39Å
74	C	93.4	Very high	91	Very high	0 Å²	0	56.6 Å²	56.6	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-62	-36.4	179.3	-70.9	0	0	0	0	112.1	L54 A70 E71 V76 C250	L54-C74 HydrophobicContact CD2-CB 3.9Å; A70-C74 WeakPolarHBondContact O-CB 3.18Å; A70-C74 PolarHBondContact O-N 3.45Å; A70-C74 PolarHBondContact O-SG 2.91Å; E71-C74 PolarHBondContact O-N 3.2Å; C74-V76 VanDerWaalsContact C-N 3.33Å; C74-V76 PolarHBondContact O-N 3.27Å; C74-C250 WeakPolarHBondContact CA-SG 3.25Å; C74-C250 HydrophobicContact CB-CB 3.66Å; C74-C250 WeakPolarHBondContact CB-SG 3.47Å; C74-C250 WeakPolarHBondContact SG-CB 3.46Å; C74-C250 CovalentContact SG-SG 2.03Å; C74-C250 PolarHBondContact SG-SG 3.18Å
75	W	92.3	Very high	90.6	Very high	47 Å²	47	60.6 Å²	60.6	18%	0.178	31%	0.309	C	S	.	.	H	α-helix	trans	-62.1	-39.5	172.9	-179.3	-104.3	0	0	0	112.5	P53 L54 E71 N72 I73 Y104 Q105 L271 V273	P53-W75 HydrophobicContact CB-CD2 4.06Å; P53-W75 HydrophobicContact CB-CE3 3.76Å; P53-W75 HydrophobicContact CB-CH2 3.68Å; P53-W75 HydrophobicContact CB-CZ2 4Å; P53-W75 HydrophobicContact CB-CZ3 3.56Å; P53-W75 HydrophobicContact CG-CD2 3.74Å; P53-W75 HydrophobicContact CG-CE3 3.81Å; P53-W75 HydrophobicContact CG-CG 4.17Å; P53-W75 HydrophobicContact CG-CH2 4.41Å; P53-W75 HydrophobicContact CG-CZ2 4.38Å; P53-W75 HydrophobicContact CG-CZ3 4.15Å; L54-W75 HydrophobicContact CB-CE3 4.26Å; E71-W75 WeakPolarHBondContact O-CB 3.23Å; E71-W75 PolarHBondContact O-N 3.37Å; N72-W75 PolarHBondContact O-N 3.19Å; I73-W75 PolarHBondContact O-N 2.63Å; W75-Y104 HydrophobicContact CD2-CE2 4.15Å; W75-Y104 HydrophobicContact CE3-CD2 4.02Å; W75-Y104 AromaticContact CE3-CE2 3.54Å; W75-Y104 HydrophobicContact CE3-CE2 3.54Å; W75-Y104 AromaticContact CH2-CD2 3.36Å; W75-Y104 HydrophobicContact CH2-CD2 3.36Å; W75-Y104 AromaticContact CH2-CE2 3.76Å; W75-Y104 HydrophobicContact CH2-CE2 3.76Å; W75-Y104 HydrophobicContact CH2-CG 4.48Å; W75-Y104 HydrophobicContact CZ2-CD2 4.1Å; W75-Y104 HydrophobicContact CZ2-CE2 4.31Å; W75-Y104 AromaticContact CZ3-CD2 3.3Å; W75-Y104 HydrophobicContact CZ3-CD2 3.3Å; W75-Y104 AromaticContact CZ3-CE2 3.32Å; W75-Y104 HydrophobicContact CZ3-CE2 3.32Å; W75-Y104 HydrophobicContact CZ3-CG 4.42Å; W75-Q105 PolarHBondContact O-NE2 3.4Å; W75-L271 HydrophobicContact CE3-CD1 4.36Å; W75-L271 HydrophobicContact CZ3-CD1 3.75Å; W75-V273 HydrophobicContact CH2-CG2 4.36Å
76	V	91.7	Very high	90.1	Very high	105 Å²	105	61.8 Å²	61.8	64%	0.636	31%	0.306	S	S	*	.	H	α-helix	trans	-83.7	-40.6	-175.6	173.6	0	0	0	0	113.2	N72 I73 C74 N78 Q105	N72-V76 WeakPolarHBondContact O-CG2 3.39Å; N72-V76 PolarHBondContact O-N 3.29Å; N72-V76 VanDerWaalsContact O-N 3.15Å; I73-V76 PolarHBondContact O-N 3.09Å; C74-V76 VanDerWaalsContact C-N 3.33Å; C74-V76 PolarHBondContact O-N 3.27Å; V76-N78 PolarHBondContact O-N 3.38Å; V76-Q105 PolarHBondContact O-NE2 3.01Å
77	Q	87.4	Confident	89.8	Confident	119 Å²	119	60.9 Å²	60.9	56%	0.556	32%	0.322	S	S	*	.	H	α-helix	trans	-75.8	-6.9	-174	-76	-175.4	-31.8	0	0	114.7	I73	I73-Q77 HydrophobicContact CG2-CG 4.19Å; I73-Q77 WeakPolarHBondContact O-CB 3.34Å; I73-Q77 PolarHBondContact O-N 3.14Å
78	N	88.4	Confident	89.4	Confident	49 Å²	49	61.3 Å²	61.3	26%	0.262	33%	0.325	S	S	.	.			trans	74.1	147.7	-165.4	-47.6	-64.2	0	0	0	112.5	V76 S102 Q105	V76-N78 PolarHBondContact O-N 3.38Å; N78-S102 WeakPolarHBondContact OD1-CA 3.22Å; N78-S102 WeakPolarHBondContact OD1-CB 3.42Å; N78-Q105 VanDerWaalsContact OD1-CD 3.25Å; N78-Q105 PolarHBondContact OD1-NE2 3.07Å; N78-Q105 PolarHBondContact OD1-OE1 3.4Å
79	T	91.9	Very high	89	Confident	0 Å²	0	58.5 Å²	58.5	0%	0	31%	0.311	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-102.3	165.3	172.4	62.9	0	0	0	0	110.4	H100 I101 Y104 T248 Y249 C250	T79-H100 WeakPolarHBondContact O-CA 3.38Å; T79-I101 PolarHBondContact O-N 3.15Å; T79-Y104 PolarHBondContact N-OH 3.38Å; T79-T248 WeakPolarHBondContact CB-OG1 3.32Å; T79-T248 VanDerWaalsContact OG1-CB 3.28Å; T79-T248 WeakPolarHBondContact OG1-CB 3.44Å; T79-T248 PolarHBondContact OG1-OG1 3.27Å; T79-T248 VanDerWaalsContact OG1-OG1 3.07Å; T79-Y249 WeakPolarHBondContact CA-O 3.26Å; T79-Y249 WeakPolarHBondContact CB-O 3.49Å; T79-C250 HydrophobicContact CG2-CB 4.23Å
80	Y	91.9	Very high	88.5	Confident	3 Å²	3	60.6 Å²	60.6	1%	0.012	33%	0.325	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.7	153.9	173.8	58.9	-88.2	0	0	0	110.6	L82 P89 V98 R99 T248 Y249 D251	Y80-L82 HydrophobicContact CD2-CD2 4.03Å; Y80-L82 HydrophobicContact CD2-CG 3.97Å; Y80-L82 HydrophobicContact CE2-CD1 3.92Å; Y80-L82 HydrophobicContact CE2-CD2 4.09Å; Y80-L82 HydrophobicContact CE2-CG 3.89Å; Y80-P89 HydrophobicContact CE2-CG 4.04Å; Y80-V98 HydrophobicContact CD2-CB 4.15Å; Y80-V98 HydrophobicContact CD2-CG1 4.26Å; Y80-V98 HydrophobicContact CD2-CG2 4.02Å; Y80-V98 HydrophobicContact CG-CB 4.38Å; Y80-V98 HydrophobicContact CG-CG2 3.87Å; Y80-R99 WeakPolarHBondContact CA-O 3.49Å; Y80-T248 WeakPolarHBondContact O-CA 3.48Å; Y80-Y249 WeakPolarHBondContact CD1-O 3.32Å; Y80-Y249 VanDerWaalsContact CE2-CB 3.46Å; Y80-Y249 HydrophobicContact CE2-CG 4.32Å; Y80-Y249 PolarHBondContact N-O 3.3Å; Y80-Y249 PolarHBondContact O-N 3.21Å; Y80-D251 WeakPolarHBondContact CE1-OD2 3.49Å; Y80-D251 PolarHBondContact OH-OD1 3.49Å; Y80-D251 PolarHBondContact OH-OD2 2.85Å
81	F	89.4	Confident	87.9	Confident	16 Å²	16	65.8 Å²	65.8	7%	0.07	35%	0.353	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-105.3	137.3	176.8	170.7	-105.3	0	0	0	110.1	L83 R99 I101 W238 G242 P245	F81-L83 HydrophobicContact CE1-CD1 3.97Å; F81-L83 HydrophobicContact CE1-CG 4.13Å; F81-L83 HydrophobicContact CZ-CG 4.41Å; F81-R99 PolarHBondContact N-O 2.99Å; F81-I101 HydrophobicContact CB-CD1 3.59Å; F81-W238 HydrophobicContact CD2-CZ3 4.19Å; F81-W238 HydrophobicContact CE2-CE3 4.11Å; F81-W238 AromaticContact CE2-CZ3 3.61Å; F81-W238 HydrophobicContact CE2-CZ3 3.61Å; F81-G242 VanDerWaalsContact CE1-CA 3.44Å; F81-P245 HydrophobicContact CB-CB 4.4Å; F81-P245 HydrophobicContact CB-CG 4.08Å; F81-P245 HydrophobicContact CD2-CB 3.44Å; F81-P245 VanDerWaalsContact CD2-CB 3.44Å; F81-P245 HydrophobicContact CD2-CG 4.05Å; F81-P245 HydrophobicContact CE2-CB 3.92Å; F81-P245 HydrophobicContact CG-CB 4.01Å; F81-P245 HydrophobicContact CG-CG 4.13Å
82	L	87.9	Confident	87.1	Confident	11 Å²	11	70.3 Å²	70.3	6%	0.058	38%	0.378	C	S	.	.			trans	-120.9	140	172.3	-61.1	176.9	0	0	0	107.8	Y80 E86 I88 V98 Y249	Y80-L82 HydrophobicContact CD2-CD2 4.03Å; Y80-L82 HydrophobicContact CD2-CG 3.97Å; Y80-L82 HydrophobicContact CE2-CD1 3.92Å; Y80-L82 HydrophobicContact CE2-CD2 4.09Å; Y80-L82 HydrophobicContact CE2-CG 3.89Å; L82-E86 HydrophobicContact CB-CB 4.46Å; L82-I88 HydrophobicContact CD1-CG1 4.2Å; L82-V98 HydrophobicContact CD2-CG1 3.8Å; L82-Y249 HydrophobicContact CB-CD2 3.99Å; L82-Y249 HydrophobicContact CB-CE2 3.85Å; L82-Y249 HydrophobicContact CD1-CD2 3.76Å; L82-Y249 HydrophobicContact CD1-CE2 3.97Å; L82-Y249 HydrophobicContact CD1-CG 4.17Å; L82-Y249 HydrophobicContact CG-CD2 3.83Å; L82-Y249 HydrophobicContact CG-CE2 4.15Å
83	L	85.6	Confident	86.6	Confident	71 Å²	71	72.7 Å²	72.7	37%	0.372	38%	0.384	S	S	.	.			trans	-68.5	154.6	169.8	-75.7	84.6	0	0	0	110	F81 N85 E86	F81-L83 HydrophobicContact CE1-CD1 3.97Å; F81-L83 HydrophobicContact CE1-CG 4.13Å; F81-L83 HydrophobicContact CZ-CG 4.41Å; L83-N85 PolarHBondContact O-N 3.14Å; L83-E86 HydrophobicContact CB-CG 4.01Å; L83-E86 WeakPolarHBondContact CD1-OE2 3.48Å; L83-E86 PolarHBondContact N-OE2 3.28Å; L83-E86 PolarHBondContact O-N 3.12Å
84	P	80.9	Confident	86	Confident	82 Å²	82	75.7 Å²	75.7	53%	0.532	40%	0.397	S	S	.	.	T	Hydrogen-bonded Turn	trans	-56.5	-25.2	-179.3	-26.2	33.5	0	0	0	115	E239	P84-E239 HydrophobicContact CG-CB 3.87Å; P84-E239 HydrophobicContact CG-CG 4.3Å; P84-E239 WeakPolarHBondContact CG-OE2 3.43Å
85	N	83.5	Confident	85.3	Confident	165 Å²	165	77.5 Å²	77.5	88%	0.882	41%	0.406	S	S	*	.	T	Hydrogen-bonded Turn	trans	-93.9	-4.5	179.7	-62.9	-28	0	0	0	113.6	L83	L83-N85 PolarHBondContact O-N 3.14Å
86	E	83.1	Confident	84.8	Confident	104 Å²	104	82.2 Å²	82.2	49%	0.486	43%	0.434	S	S	.	.	S	Bend	trans	-89.4	139.1	179.8	-71.6	175.6	161.1	0	0	110.6	L82 L83	L82-E86 HydrophobicContact CB-CB 4.46Å; L83-E86 HydrophobicContact CB-CG 4.01Å; L83-E86 WeakPolarHBondContact CD1-OE2 3.48Å; L83-E86 PolarHBondContact N-OE2 3.28Å; L83-E86 PolarHBondContact O-N 3.12Å
87	A	85.6	Confident	84.2	Confident	88 Å²	88	86.9 Å²	86.9	73%	0.727	44%	0.44	S	S	*	.	P	Polyproline II helix	trans	-74.4	153.2	174.8	0	0	0	0	0	111.1
88	I	85.9	Confident	84	Confident	73 Å²	73	82.4 Å²	82.4	37%	0.374	42%	0.421	S	S	.	.	P	Polyproline II helix	trans	-66.4	129.4	172.8	-61	173	0	0	0	108	L82 E90 T266	L82-I88 HydrophobicContact CD1-CG1 4.2Å; I88-E90 PolarHBondContact O-N 2.82Å; I88-T266 HydrophobicContact CG2-CG2 3.78Å
89	P	84.9	Confident	83.7	Confident	10 Å²	10	85.1 Å²	85.1	7%	0.065	43%	0.427	C	S	.	.	P	Polyproline II helix	trans	-66	126.8	-178.6	27.2	-34.8	0	0	0	110.9	Y80 E94 M95 V98	Y80-P89 HydrophobicContact CE2-CG 4.04Å; P89-E94 WeakPolarHBondContact CA-OE2 3.42Å; P89-E94 HydrophobicContact CB-CB 3.68Å; P89-M95 HydrophobicContact CB-CG 4.16Å; P89-M95 HydrophobicContact CG-CG 4.11Å; P89-V98 HydrophobicContact CG-CG1 4.18Å
90	E	80.2	Confident	83.4	Confident	179 Å²	179	89.9 Å²	89.9	84%	0.836	45%	0.45	S	S	*	.			trans	-96.2	-34.2	178.2	-66.3	-172.2	174.9	0	0	112	I88 E94	I88-E90 PolarHBondContact O-N 2.82Å; E90-E94 PolarHBondContact N-OE2 3.34Å
91	D	81.3	Confident	83.2	Confident	110 Å²	110	90 Å²	90	59%	0.588	45%	0.45	S	S	*	.	S	Bend	trans	-100.6	149.5	-175.8	-75.5	-34.7	0	0	0	112.7	F93 E94 M95	D91-F93 PolarHBondContact O-N 3.48Å; D91-F93 VanDerWaalsContact O-N 3.1Å; D91-E94 HydrophobicContact CB-CG 4.46Å; D91-E94 PolarHBondContact O-N 3.1Å; D91-M95 PolarHBondContact O-N 3.27Å; D91-M95 VanDerWaalsContact O-N 3.14Å
92	D	78.8	Confident	83.2	Confident	114 Å²	114	91.8 Å²	91.8	61%	0.61	47%	0.465	S	S	*	.	H	α-helix	trans	-58.3	-27.1	176.2	-71.2	-35	0	0	0	112.2	L96 K253	D92-L96 WeakPolarHBondContact O-CG 3.24Å; D92-L96 PolarHBondContact O-N 3.34Å; D92-K253 IonicContact OD1-NZ 3.44Å
93	F	81.1	Confident	83.3	Confident	147 Å²	147	92.2 Å²	92.2	65%	0.645	47%	0.466	S	S	*	.	H	α-helix	trans	-71.1	-36.3	176.4	-173.9	-99.8	0	0	0	112.7	D91 L96	D91-F93 PolarHBondContact O-N 3.48Å; D91-F93 VanDerWaalsContact O-N 3.1Å; F93-L96 PolarHBondContact O-N 3.14Å
94	E	80.1	Confident	83.5	Confident	96 Å²	96	88.8 Å²	88.8	45%	0.449	45%	0.448	S	S	.	.	H	α-helix	trans	-72	-36.7	176.5	-63.2	-170.4	147.3	0	0	110.9	P89 E90 D91 L96 R97 V98	P89-E94 WeakPolarHBondContact CA-OE2 3.42Å; P89-E94 HydrophobicContact CB-CB 3.68Å; E90-E94 PolarHBondContact N-OE2 3.34Å; D91-E94 HydrophobicContact CB-CG 4.46Å; D91-E94 PolarHBondContact O-N 3.1Å; E94-L96 PolarHBondContact O-N 2.93Å; E94-R97 WeakPolarHBondContact O-CB 3.35Å; E94-R97 PolarHBondContact O-N 2.97Å; E94-V98 PolarHBondContact O-N 3.4Å
95	M	80	Confident	83.9	Confident	39 Å²	39	87.1 Å²	87.1	19%	0.192	43%	0.433	C	S	.	.	H	α-helix	trans	-59.6	-27.8	172.5	-83.3	-147.1	-103.3	0	0	113.7	P89 D91 R97 V98 D251	P89-M95 HydrophobicContact CB-CG 4.16Å; P89-M95 HydrophobicContact CG-CG 4.11Å; D91-M95 PolarHBondContact O-N 3.27Å; D91-M95 VanDerWaalsContact O-N 3.14Å; M95-R97 PolarHBondContact O-N 2.93Å; M95-V98 WeakPolarHBondContact O-CG2 3.39Å; M95-D251 VanDerWaalsContact SD-OD2 3.33Å
96	L	80.4	Confident	84.3	Confident	146 Å²	146	85.5 Å²	85.5	76%	0.764	42%	0.415	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.2	-18.5	175.1	-69.2	168.6	0	0	0	113.1	D92 F93 E94	D92-L96 WeakPolarHBondContact O-CG 3.24Å; D92-L96 PolarHBondContact O-N 3.34Å; F93-L96 PolarHBondContact O-N 3.14Å; E94-L96 PolarHBondContact O-N 2.93Å
97	R	80.2	Confident	84.8	Confident	203 Å²	203	80.6 Å²	80.6	77%	0.766	39%	0.392	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.6	-22.3	-179	-167.4	-179.3	-66.8	177.3	2.1	112.6	E94 M95	E94-R97 WeakPolarHBondContact O-CB 3.35Å; E94-R97 PolarHBondContact O-N 2.97Å; M95-R97 PolarHBondContact O-N 2.93Å
98	V	83.4	Confident	85.1	Confident	25 Å²	25	77.6 Å²	77.6	15%	0.152	37%	0.367	C	S	.	.	S	Bend	trans	-70.7	146.4	-176.5	-61.4	0	0	0	0	112	Y80 L82 P89 E94 M95 H100	Y80-V98 HydrophobicContact CD2-CB 4.15Å; Y80-V98 HydrophobicContact CD2-CG1 4.26Å; Y80-V98 HydrophobicContact CD2-CG2 4.02Å; Y80-V98 HydrophobicContact CG-CB 4.38Å; Y80-V98 HydrophobicContact CG-CG2 3.87Å; L82-V98 HydrophobicContact CD2-CG1 3.8Å; P89-V98 HydrophobicContact CG-CG1 4.18Å; E94-V98 PolarHBondContact O-N 3.4Å; M95-V98 WeakPolarHBondContact O-CG2 3.39Å; V98-H100 PolarHBondContact O-N 3.42Å
99	R	81.8	Confident	85.5	Confident	105 Å²	105	78.9 Å²	78.9	40%	0.396	37%	0.373	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-81	103.7	176.7	-174	179.7	-180	179.8	0.7	109.7	Y80 F81 I217 G218	Y80-R99 WeakPolarHBondContact CA-O 3.49Å; F81-R99 PolarHBondContact N-O 2.99Å; R99-I217 PolarHBondContact NH2-O 3.07Å; R99-G218 PolarHBondContact NH2-O 2.69Å
100	H	86.4	Confident	86	Confident	101 Å²	101	80.9 Å²	80.9	47%	0.468	38%	0.383	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-71.2	142.6	169.3	-69.1	-80.1	0	0	0	111.8	T79 V98	T79-H100 WeakPolarHBondContact O-CA 3.38Å; V98-H100 PolarHBondContact O-N 3.42Å
101	I	87.3	Confident	86.7	Confident	5 Å²	5	72.4 Å²	72.4	3%	0.026	34%	0.343	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-117	108.3	-175.7	-57.4	179.9	0	0	0	108	T79 F81 Y103 Y104 P245 T248	T79-I101 PolarHBondContact O-N 3.15Å; F81-I101 HydrophobicContact CB-CD1 3.59Å; I101-Y103 HydrophobicContact CG2-CD1 3.71Å; I101-Y103 HydrophobicContact CG2-CE1 3.39Å; I101-Y104 HydrophobicContact CB-CE1 4.19Å; I101-Y104 HydrophobicContact CG2-CD1 3.62Å; I101-Y104 HydrophobicContact CG2-CE1 3.72Å; I101-Y104 WeakPolarHBondContact O-CE1 3.48Å; I101-P245 HydrophobicContact CD1-CG 3.22Å; I101-T248 HydrophobicContact CD1-CG2 4.02Å
102	S	88.5	Confident	87.4	Confident	53 Å²	53	69 Å²	69	37%	0.371	33%	0.331	S	S	.	.			trans	-115.6	-13.9	178.2	60.3	0	0	0	0	113.2	N78 Y104 Q105	N78-S102 WeakPolarHBondContact OD1-CA 3.22Å; N78-S102 WeakPolarHBondContact OD1-CB 3.42Å; S102-Y104 VanDerWaalsContact C-N 3.26Å; S102-Y104 PolarHBondContact O-N 3.42Å; S102-Y104 VanDerWaalsContact O-N 3.14Å; S102-Q105 WeakPolarHBondContact O-CB 3.22Å; S102-Q105 PolarHBondContact O-N 3.1Å; S102-Q105 VanDerWaalsContact O-N 3.12Å
103	Y	90	Very high	88.1	Confident	20 Å²	20	65.4 Å²	65.4	8%	0.078	32%	0.321	C	S	.	.	H	α-helix	trans	-62.7	-29.2	-169.1	69.7	-108	0	0	0	113.4	I101 Q105 W106 V107 F216 F244 N274 I277	I101-Y103 HydrophobicContact CG2-CD1 3.71Å; I101-Y103 HydrophobicContact CG2-CE1 3.39Å; Y103-Q105 PolarHBondContact O-N 2.88Å; Y103-W106 PolarHBondContact O-N 3.29Å; Y103-V107 PolarHBondContact O-N 3.39Å; Y103-F216 HydrophobicContact CD2-CE1 4.43Å; Y103-F216 HydrophobicContact CG-CE1 4.43Å; Y103-F216 WeakPolarHBondContact O-CE1 3.38Å; Y103-F216 WeakPolarHBondContact O-CZ 3.27Å; Y103-F244 HydrophobicContact CE2-CD1 4.12Å; Y103-F244 HydrophobicContact CE2-CE1 4.23Å; Y103-F244 WeakPolarHBondContact OH-CA 3.38Å; Y103-N274 WeakPolarHBondContact CE2-OD1 3.36Å; Y103-N274 VanDerWaalsContact CZ-OD1 3.3Å; Y103-N274 PolarHBondContact OH-ND2 3.34Å; Y103-N274 PolarHBondContact OH-OD1 3.41Å; Y103-I277 HydrophobicContact CE2-CD1 4.43Å; Y103-I277 HydrophobicContact CE2-CG2 4.39Å
104	Y	89.7	Confident	88.8	Confident	0 Å²	0	58.7 Å²	58.7	0%	0	29%	0.291	C	S	.	.	H	α-helix	trans	-67.1	-24.4	-179.3	60.1	-101.8	0	0	0	112.9	W75 T79 I101 S102 V107 L271	W75-Y104 HydrophobicContact CD2-CE2 4.15Å; W75-Y104 HydrophobicContact CE3-CD2 4.02Å; W75-Y104 AromaticContact CE3-CE2 3.54Å; W75-Y104 HydrophobicContact CE3-CE2 3.54Å; W75-Y104 AromaticContact CH2-CD2 3.36Å; W75-Y104 HydrophobicContact CH2-CD2 3.36Å; W75-Y104 AromaticContact CH2-CE2 3.76Å; W75-Y104 HydrophobicContact CH2-CE2 3.76Å; W75-Y104 HydrophobicContact CH2-CG 4.48Å; W75-Y104 HydrophobicContact CZ2-CD2 4.1Å; W75-Y104 HydrophobicContact CZ2-CE2 4.31Å; W75-Y104 AromaticContact CZ3-CD2 3.3Å; W75-Y104 HydrophobicContact CZ3-CD2 3.3Å; W75-Y104 AromaticContact CZ3-CE2 3.32Å; W75-Y104 HydrophobicContact CZ3-CE2 3.32Å; W75-Y104 HydrophobicContact CZ3-CG 4.42Å; T79-Y104 PolarHBondContact N-OH 3.38Å; I101-Y104 HydrophobicContact CB-CE1 4.19Å; I101-Y104 HydrophobicContact CG2-CD1 3.62Å; I101-Y104 HydrophobicContact CG2-CE1 3.72Å; I101-Y104 WeakPolarHBondContact O-CE1 3.48Å; S102-Y104 VanDerWaalsContact C-N 3.26Å; S102-Y104 PolarHBondContact O-N 3.42Å; S102-Y104 VanDerWaalsContact O-N 3.14Å; Y104-V107 WeakPolarHBondContact O-CG1 3.47Å; Y104-L271 HydrophobicContact CD1-CD2 3.59Å; Y104-L271 HydrophobicContact CD2-CD1 4.33Å; Y104-L271 HydrophobicContact CE1-CD2 3.84Å; Y104-L271 HydrophobicContact CE2-CD1 4.38Å; Y104-L271 HydrophobicContact CG-CD1 4.42Å; Y104-L271 HydrophobicContact CG-CD2 4.08Å
105	Q	89.5	Confident	89.5	Confident	47 Å²	47	54.5 Å²	54.5	22%	0.22	27%	0.273	C	S	.	.	H	α-helix	trans	-74.2	-38.5	175.6	-56.8	169.4	-20.2	0	0	111	W75 V76 N78 S102 Y103	W75-Q105 PolarHBondContact O-NE2 3.4Å; V76-Q105 PolarHBondContact O-NE2 3.01Å; N78-Q105 VanDerWaalsContact OD1-CD 3.25Å; N78-Q105 PolarHBondContact OD1-NE2 3.07Å; N78-Q105 PolarHBondContact OD1-OE1 3.4Å; S102-Q105 WeakPolarHBondContact O-CB 3.22Å; S102-Q105 PolarHBondContact O-N 3.1Å; S102-Q105 VanDerWaalsContact O-N 3.12Å; Y103-Q105 PolarHBondContact O-N 2.88Å
106	W	92.8	Very high	90.2	Very high	130 Å²	130	59.1 Å²	59.1	49%	0.492	30%	0.296	S	S	.	.	H	α-helix	trans	-94.3	-8.1	-172.4	-63.1	97.3	0	0	0	113.8	Y103 A108 I109 I110 F216	Y103-W106 PolarHBondContact O-N 3.29Å; W106-A108 VanDerWaalsContact C-N 3.31Å; W106-A108 PolarHBondContact O-N 3.46Å; W106-I109 HydrophobicContact CE3-CD1 3.53Å; W106-I109 HydrophobicContact CZ3-CD1 3.67Å; W106-I109 PolarHBondContact O-N 2.87Å; W106-I110 WeakPolarHBondContact O-CG1 3.12Å; W106-I110 PolarHBondContact O-N 2.88Å; W106-F216 HydrophobicContact CB-CE2 4Å; W106-F216 HydrophobicContact CB-CZ 3.93Å
107	V	93	Very high	90.8	Very high	1 Å²	1	56 Å²	56	1%	0.006	28%	0.278	C	S	.	.	H	α-helix	trans	-53.2	-44.6	-172.6	71.4	0	0	0	0	113.2	I44 Y103 Y104 I109 I110 L111 F216 I277 Y281	I44-V107 HydrophobicContact CD1-CG1 4.41Å; I44-V107 HydrophobicContact CG2-CG1 4.24Å; Y103-V107 PolarHBondContact O-N 3.39Å; Y104-V107 WeakPolarHBondContact O-CG1 3.47Å; V107-I109 PolarHBondContact O-N 3.04Å; V107-I110 PolarHBondContact O-N 3.31Å; V107-L111 HydrophobicContact CG2-CD1 4.22Å; V107-L111 HydrophobicContact CG2-CG 4.45Å; V107-L111 WeakPolarHBondContact O-CB 3.45Å; V107-L111 VanDerWaalsContact O-CG 3.26Å; V107-L111 WeakPolarHBondContact O-CG 3.47Å; V107-L111 PolarHBondContact O-N 3.07Å; V107-F216 HydrophobicContact CB-CE1 4.3Å; V107-F216 HydrophobicContact CG2-CE1 4.4Å; V107-I277 HydrophobicContact CB-CD1 4.04Å; V107-I277 HydrophobicContact CG1-CD1 3.76Å; V107-I277 HydrophobicContact CG1-CG1 4.17Å; V107-I277 HydrophobicContact CG2-CD1 4.17Å; V107-I277 HydrophobicContact CG2-CG1 4.17Å; V107-I277 HydrophobicContact CG2-CG2 4.09Å; V107-Y281 HydrophobicContact CG2-CE2 3.62Å
108	A	92.8	Very high	91.5	Very high	25 Å²	25	46.3 Å²	46.3	21%	0.207	24%	0.242	C	C	.	.	H	α-helix	trans	-67.6	-37.1	-177.9	0	0	0	0	0	111.9	I41 W106 A112	I41-A108 HydrophobicContact CG2-CB 4.47Å; W106-A108 VanDerWaalsContact C-N 3.31Å; W106-A108 PolarHBondContact O-N 3.46Å; A108-A112 WeakPolarHBondContact O-CB 3.49Å; A108-A112 PolarHBondContact O-N 3.21Å
109	I	93.3	Very high	91.9	Very high	100 Å²	100	46.2 Å²	46.2	51%	0.513	24%	0.239	S	C	.	.	H	α-helix	trans	-68.9	-44.3	177.9	-64.1	167.6	0	0	0	109.9	W106 V107 A112 G113	W106-I109 HydrophobicContact CE3-CD1 3.53Å; W106-I109 HydrophobicContact CZ3-CD1 3.67Å; W106-I109 PolarHBondContact O-N 2.87Å; V107-I109 PolarHBondContact O-N 3.04Å; I109-A112 WeakPolarHBondContact O-CB 3.28Å; I109-A112 PolarHBondContact O-N 3.19Å; I109-G113 PolarHBondContact O-N 3.03Å
110	I	94.6	Very high	92.4	Very high	53 Å²	53	44.8 Å²	44.8	27%	0.272	24%	0.242	S	C	.	.	H	α-helix	trans	-63	-47.5	176.6	-64.5	-56.3	0	0	0	110.5	W106 V107 A112 G113 Q114 V212 F216	W106-I110 WeakPolarHBondContact O-CG1 3.12Å; W106-I110 PolarHBondContact O-N 2.88Å; V107-I110 PolarHBondContact O-N 3.31Å; I110-A112 VanDerWaalsContact C-N 3.28Å; I110-A112 PolarHBondContact O-N 3.17Å; I110-G113 CarbonylContact O-C 3.6Å; I110-G113 WeakPolarHBondContact O-CA 3.37Å; I110-G113 PolarHBondContact O-N 3.18Å; I110-Q114 HydrophobicContact CG2-CG 4.29Å; I110-Q114 WeakPolarHBondContact O-CG 3.31Å; I110-Q114 PolarHBondContact O-N 3.35Å; I110-V212 HydrophobicContact CG2-CG1 4.26Å; I110-F216 HydrophobicContact CB-CE2 4.44Å; I110-F216 HydrophobicContact CB-CZ 4.42Å; I110-F216 HydrophobicContact CD1-CD2 4.5Å; I110-F216 HydrophobicContact CD1-CE2 4.35Å; I110-F216 HydrophobicContact CG1-CD2 3.86Å; I110-F216 HydrophobicContact CG1-CE2 3.49Å; I110-F216 VanDerWaalsContact CG1-CE2 3.49Å; I110-F216 HydrophobicContact CG1-CZ 3.83Å
111	L	95.5	Very high	92.7	Very high	0 Å²	0	40.1 Å²	40.1	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-56.9	-41.7	175.2	-74.3	178	0	0	0	111.7	I37 I41 I44 V107 G113 Q114 A115 L284	I37-L111 HydrophobicContact CG2-CB 3.8Å; I37-L111 HydrophobicContact CG2-CD2 4.23Å; I37-L111 WeakPolarHBondContact CG2-O 3.12Å; I41-L111 HydrophobicContact CD1-CB 3.87Å; I41-L111 HydrophobicContact CG1-CB 3.67Å; I41-L111 HydrophobicContact CG1-CD1 4.21Å; I44-L111 HydrophobicContact CD1-CD1 3.86Å; V107-L111 HydrophobicContact CG2-CD1 4.22Å; V107-L111 HydrophobicContact CG2-CG 4.45Å; V107-L111 WeakPolarHBondContact O-CB 3.45Å; V107-L111 VanDerWaalsContact O-CG 3.26Å; V107-L111 WeakPolarHBondContact O-CG 3.47Å; V107-L111 PolarHBondContact O-N 3.07Å; L111-G113 VanDerWaalsContact C-N 3.33Å; L111-G113 PolarHBondContact O-N 2.79Å; L111-Q114 WeakPolarHBondContact O-CB 3.28Å; L111-Q114 PolarHBondContact O-N 2.9Å; L111-A115 PolarHBondContact O-N 3.4Å; L111-L284 HydrophobicContact CD2-CD1 3.61Å
112	A	95.2	Very high	92.8	Very high	40 Å²	40	40 Å²	40	33%	0.331	22%	0.22	S	C	.	.	H	α-helix	trans	-61.2	-42.6	174.8	0	0	0	0	0	111.7	I41 A108 I109 I110 A115 M116	I41-A112 HydrophobicContact CD1-CB 4.01Å; A108-A112 WeakPolarHBondContact O-CB 3.49Å; A108-A112 PolarHBondContact O-N 3.21Å; I109-A112 WeakPolarHBondContact O-CB 3.28Å; I109-A112 PolarHBondContact O-N 3.19Å; I110-A112 VanDerWaalsContact C-N 3.28Å; I110-A112 PolarHBondContact O-N 3.17Å; A112-A115 PolarHBondContact O-N 3.47Å; A112-M116 WeakPolarHBondContact O-CG 3.43Å; A112-M116 PolarHBondContact O-N 2.96Å
113	G	95.4	Very high	92.9	Very high	38 Å²	38	39.4 Å²	39.4	39%	0.392	21%	0.213	S	C	.	.	H	α-helix	trans	-60.8	-42.2	172.8	0	0	0	0	0	113.2	I109 I110 L111 M116 M117	I109-G113 PolarHBondContact O-N 3.03Å; I110-G113 CarbonylContact O-C 3.6Å; I110-G113 WeakPolarHBondContact O-CA 3.37Å; I110-G113 PolarHBondContact O-N 3.18Å; L111-G113 VanDerWaalsContact C-N 3.33Å; L111-G113 PolarHBondContact O-N 2.79Å; G113-M116 PolarHBondContact O-N 3.12Å; G113-M117 WeakPolarHBondContact O-CB 3.49Å; G113-M117 PolarHBondContact O-N 3.45Å
114	Q	95.5	Very high	92.9	Very high	5 Å²	5	40.3 Å²	40.3	2%	0.023	22%	0.219	C	C	.	.	H	α-helix	trans	-62.7	-43.6	175.5	-66	-169.8	-20.5	0	0	111.6	I37 I110 L111 M116 M117 A118 Q209 V212	I37-Q114 HydrophobicContact CD1-CB 4.34Å; I110-Q114 HydrophobicContact CG2-CG 4.29Å; I110-Q114 WeakPolarHBondContact O-CG 3.31Å; I110-Q114 PolarHBondContact O-N 3.35Å; L111-Q114 WeakPolarHBondContact O-CB 3.28Å; L111-Q114 PolarHBondContact O-N 2.9Å; Q114-M116 VanDerWaalsContact C-N 3.33Å; Q114-M116 PolarHBondContact O-N 3.03Å; Q114-M117 PolarHBondContact O-N 3.33Å; Q114-A118 PolarHBondContact O-N 2.81Å; Q114-Q209 VanDerWaalsContact CB-OE1 3.27Å; Q114-V212 HydrophobicContact CG-CG1 4.39Å
115	A	94.9	Very high	92.9	Very high	9 Å²	9	40.6 Å²	40.6	7%	0.074	22%	0.221	C	C	.	.	H	α-helix	trans	-60.1	-42.5	175.1	0	0	0	0	0	111.5	I37 L111 A112 A118	I37-A115 HydrophobicContact CB-CB 4.14Å; I37-A115 HydrophobicContact CD1-CB 4.27Å; I37-A115 HydrophobicContact CG2-CB 3.88Å; L111-A115 PolarHBondContact O-N 3.4Å; A112-A115 PolarHBondContact O-N 3.47Å; A115-A118 PolarHBondContact O-N 3.26Å
116	M	93.7	Very high	92.7	Very high	136 Å²	136	41 Å²	41	67%	0.67	22%	0.22	S	C	*	.	H	α-helix	trans	-65.1	-42.8	175.2	-69.6	176	65.4	0	0	112.2	A112 G113 Q114 A118 W119	A112-M116 WeakPolarHBondContact O-CG 3.43Å; A112-M116 PolarHBondContact O-N 2.96Å; G113-M116 PolarHBondContact O-N 3.12Å; Q114-M116 VanDerWaalsContact C-N 3.33Å; Q114-M116 PolarHBondContact O-N 3.03Å; M116-A118 VanDerWaalsContact C-N 3.27Å; M116-A118 PolarHBondContact O-N 3.38Å; M116-W119 WeakPolarHBondContact O-CB 3.33Å; M116-W119 PolarHBondContact O-N 3.02Å; M116-W119 VanDerWaalsContact O-N 3.07Å
117	M	94.1	Very high	92.5	Very high	79 Å²	79	38.5 Å²	38.5	39%	0.389	22%	0.219	S	C	.	.	H	α-helix	trans	-63.5	-33.8	-179.9	-167.9	-178.3	170.9	0	0	111.8	G113 Q114 W119 V120 N205 Q209	G113-M117 WeakPolarHBondContact O-CB 3.49Å; G113-M117 PolarHBondContact O-N 3.45Å; Q114-M117 PolarHBondContact O-N 3.33Å; M117-W119 PolarHBondContact O-N 3.39Å; M117-V120 WeakPolarHBondContact O-CB 3.31Å; M117-V120 PolarHBondContact O-N 3.37Å; M117-V120 VanDerWaalsContact O-N 3.1Å; M117-N205 WeakPolarHBondContact CG-OD1 3.47Å; M117-N205 PolarHBondContact O-OD1 3.02Å; M117-Q209 PolarHBondContact SD-NE2 3.42Å
118	A	93.1	Very high	92.2	Very high	0 Å²	0	44.6 Å²	44.6	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-61.4	-24.9	173.7	0	0	0	0	0	114.1	Y30 Q114 A115 M116	Y30-A118 WeakPolarHBondContact CB-O 3.4Å; Q114-A118 PolarHBondContact O-N 2.81Å; A115-A118 PolarHBondContact O-N 3.26Å; M116-A118 VanDerWaalsContact C-N 3.27Å; M116-A118 PolarHBondContact O-N 3.38Å
119	W	92	Very high	91.9	Very high	24 Å²	24	43.8 Å²	43.8	9%	0.091	24%	0.235	C	C	.	.	H	α-helix	trans	-83	-19.8	176	-81.1	74	0	0	0	113.8	F13 V15 Y30 S34 M116 M117 H122 V123	F13-W119 HydrophobicContact CB-CH2 4.46Å; F13-W119 AromaticContact CD1-CD2 3.77Å; F13-W119 HydrophobicContact CD1-CD2 3.77Å; F13-W119 AromaticContact CD1-CE3 3.65Å; F13-W119 HydrophobicContact CD1-CE3 3.65Å; F13-W119 HydrophobicContact CD1-CG 4.41Å; F13-W119 HydrophobicContact CD1-CH2 4.14Å; F13-W119 HydrophobicContact CD1-CZ2 4.25Å; F13-W119 AromaticContact CD1-CZ3 3.85Å; F13-W119 HydrophobicContact CD1-CZ3 3.85Å; F13-W119 HydrophobicContact CE1-CB 4.35Å; F13-W119 AromaticContact CE1-CD2 3.91Å; F13-W119 HydrophobicContact CE1-CD2 3.91Å; F13-W119 AromaticContact CE1-CE3 3.96Å; F13-W119 HydrophobicContact CE1-CE3 3.96Å; F13-W119 HydrophobicContact CE1-CG 4.09Å; F13-W119 WeakPolarHBondContact O-CH2 3.31Å; V15-W119 HydrophobicContact CB-CH2 4.5Å; V15-W119 HydrophobicContact CG2-CH2 3.65Å; V15-W119 HydrophobicContact CG2-CZ3 3.94Å; Y30-W119 HydrophobicContact CD2-CD2 4.29Å; Y30-W119 HydrophobicContact CD2-CE3 4.24Å; Y30-W119 HydrophobicContact CD2-CH2 4.03Å; Y30-W119 HydrophobicContact CD2-CZ2 4.07Å; Y30-W119 HydrophobicContact CD2-CZ3 4.11Å; Y30-W119 HydrophobicContact CE2-CH2 4.31Å; Y30-W119 HydrophobicContact CE2-CZ3 4.46Å; Y30-W119 PolarHBondContact O-NE1 3.4Å; S34-W119 VanDerWaalsContact CB-NE1 3.35Å; S34-W119 PolarHBondContact OG-NE1 2.7Å; M116-W119 WeakPolarHBondContact O-CB 3.33Å; M116-W119 PolarHBondContact O-N 3.02Å; M116-W119 VanDerWaalsContact O-N 3.07Å; M117-W119 PolarHBondContact O-N 3.39Å; W119-H122 WeakPolarHBondContact O-CB 3.36Å; W119-H122 PolarHBondContact O-N 3.44Å; W119-H122 VanDerWaalsContact O-N 3.09Å; W119-V123 WeakPolarHBondContact O-CG2 3.23Å; W119-V123 PolarHBondContact O-N 3.5Å
120	V	92.3	Very high	91.4	Very high	75 Å²	75	46.5 Å²	46.5	46%	0.455	24%	0.243	S	C	.	.	H	α-helix	trans	-54	-49.5	-172.9	172.6	0	0	0	0	112.6	M117 H122 V123 L124	M117-V120 WeakPolarHBondContact O-CB 3.31Å; M117-V120 PolarHBondContact O-N 3.37Å; M117-V120 VanDerWaalsContact O-N 3.1Å; V120-H122 VanDerWaalsContact C-N 3.29Å; V120-H122 PolarHBondContact O-N 2.81Å; V120-V123 PolarHBondContact O-N 3.3Å; V120-L124 HydrophobicContact CG1-CD1 4.09Å; V120-L124 HydrophobicContact CG1-CG 4.33Å; V120-L124 WeakPolarHBondContact O-CG 3.49Å; V120-L124 PolarHBondContact O-N 2.91Å
121	P	92.6	Very high	90.9	Very high	3 Å²	3	52.4 Å²	52.4	2%	0.019	26%	0.262	C	S	.	.	H	α-helix	trans	-62.5	-35.8	-179.7	-21.9	34.4	0	0	0	113	L124 W125 V198 F201 F202 N205	P121-L124 PolarHBondContact O-N 3.42Å; P121-W125 PolarHBondContact O-N 3.48Å; P121-W125 VanDerWaalsContact O-N 3.07Å; P121-V198 HydrophobicContact CB-CG1 4.29Å; P121-V198 WeakPolarHBondContact O-CG1 3.37Å; P121-F201 HydrophobicContact CB-CB 4.09Å; P121-F201 HydrophobicContact CG-CB 4.16Å; P121-F202 HydrophobicContact CB-CD1 3.82Å; P121-F202 HydrophobicContact CB-CD2 3.63Å; P121-F202 HydrophobicContact CB-CE1 3.83Å; P121-F202 HydrophobicContact CB-CE2 3.65Å; P121-F202 HydrophobicContact CB-CG 3.73Å; P121-F202 HydrophobicContact CB-CZ 3.76Å; P121-F202 HydrophobicContact CG-CD1 3.97Å; P121-F202 HydrophobicContact CG-CE1 4.21Å; P121-F202 HydrophobicContact CG-CG 4.15Å; P121-N205 HydrophobicContact CG-CB 4.25Å
122	H	90.2	Very high	90.4	Very high	3 Å²	3	52.8 Å²	52.8	1%	0.014	26%	0.264	C	S	.	.	H	α-helix	trans	-67.5	-43.3	176.3	-176.1	72	0	0	0	111.8	Y30 W119 V120 L124 W125 R126 F202	Y30-H122 HydrophobicContact CD1-CB 3.91Å; Y30-H122 AromaticContact CD1-CG 3.93Å; Y30-H122 AromaticContact CD1-ND1 3.9Å; Y30-H122 AromaticContact CE1-ND1 3.61Å; Y30-H122 HydrophobicContact CG-CB 4.01Å; Y30-H122 AromaticContact CZ-ND1 3.98Å; W119-H122 WeakPolarHBondContact O-CB 3.36Å; W119-H122 PolarHBondContact O-N 3.44Å; W119-H122 VanDerWaalsContact O-N 3.09Å; V120-H122 VanDerWaalsContact C-N 3.29Å; V120-H122 PolarHBondContact O-N 2.81Å; H122-L124 VanDerWaalsContact C-N 3.32Å; H122-L124 PolarHBondContact O-N 2.87Å; H122-W125 WeakPolarHBondContact O-CB 3.44Å; H122-W125 PolarHBondContact O-N 3.03Å; H122-R126 WeakPolarHBondContact O-CG 3.37Å; H122-R126 PolarHBondContact O-N 3.43Å; H122-F202 HydrophobicContact CB-CZ 4.18Å
123	V	90	Very high	89.9	Confident	39 Å²	39	51.1 Å²	51.1	24%	0.236	25%	0.25	C	C	.	.	H	α-helix	trans	-61.4	-42.4	175.5	173.4	0	0	0	0	110.8	L12 W119 V120 W125 R126 V127	L12-V123 HydrophobicContact CD2-CB 4.43Å; L12-V123 HydrophobicContact CD2-CG1 3.97Å; L12-V123 HydrophobicContact CD2-CG2 3.73Å; L12-V123 HydrophobicContact CG-CG2 4.41Å; W119-V123 WeakPolarHBondContact O-CG2 3.23Å; W119-V123 PolarHBondContact O-N 3.5Å; V120-V123 PolarHBondContact O-N 3.3Å; V123-W125 VanDerWaalsContact C-N 3.34Å; V123-W125 PolarHBondContact O-N 3.24Å; V123-R126 PolarHBondContact O-N 3.26Å; V123-V127 HydrophobicContact CG1-CG2 4.09Å; V123-V127 WeakPolarHBondContact O-CB 3.42Å; V123-V127 VanDerWaalsContact O-CG2 3.3Å; V123-V127 WeakPolarHBondContact O-CG2 3.45Å; V123-V127 PolarHBondContact O-N 3.01Å
124	L	90.5	Very high	89.4	Confident	39 Å²	39	53.2 Å²	53.2	20%	0.204	26%	0.255	C	S	.	.	H	α-helix	trans	-58.2	-44.4	175.3	-70.9	175.5	0	0	0	111.9	V120 P121 H122 R126 V127 W128 F201	V120-L124 HydrophobicContact CG1-CD1 4.09Å; V120-L124 HydrophobicContact CG1-CG 4.33Å; V120-L124 WeakPolarHBondContact O-CG 3.49Å; V120-L124 PolarHBondContact O-N 2.91Å; P121-L124 PolarHBondContact O-N 3.42Å; H122-L124 VanDerWaalsContact C-N 3.32Å; H122-L124 PolarHBondContact O-N 2.87Å; L124-R126 PolarHBondContact O-N 2.95Å; L124-V127 PolarHBondContact O-N 3.5Å; L124-W128 HydrophobicContact CB-CD2 4.47Å; L124-W128 HydrophobicContact CB-CE3 4.03Å; L124-W128 HydrophobicContact CB-CZ3 4.13Å; L124-W128 HydrophobicContact CD1-CH2 4.26Å; L124-W128 HydrophobicContact CD1-CZ3 4.29Å; L124-W128 HydrophobicContact CD2-CD2 4.41Å; L124-W128 HydrophobicContact CD2-CE3 4.47Å; L124-W128 HydrophobicContact CD2-CH2 3.9Å; L124-W128 HydrophobicContact CD2-CZ2 3.75Å; L124-W128 HydrophobicContact CD2-CZ3 4.26Å; L124-W128 HydrophobicContact CG-CH2 4.49Å; L124-W128 HydrophobicContact CG-CZ3 4.47Å; L124-W128 VanDerWaalsContact O-CB 3.29Å; L124-W128 WeakPolarHBondContact O-CB 3.34Å; L124-W128 PolarHBondContact O-N 3.41Å; L124-F201 HydrophobicContact CD1-CD2 4.16Å; L124-F201 HydrophobicContact CD1-CE2 4.37Å; L124-F201 HydrophobicContact CD1-CG 4.37Å
125	W	90	Very high	88.9	Confident	7 Å²	7	53.9 Å²	53.9	3%	0.027	26%	0.259	C	S	.	.	H	α-helix	trans	-58.5	-47.2	174.7	176.2	-116.9	0	0	0	112.6	V22 P121 H122 V123 S129 V132 I191 F195 V198 F348	V22-W125 HydrophobicContact CG2-CZ2 3.86Å; P121-W125 PolarHBondContact O-N 3.48Å; P121-W125 VanDerWaalsContact O-N 3.07Å; H122-W125 WeakPolarHBondContact O-CB 3.44Å; H122-W125 PolarHBondContact O-N 3.03Å; V123-W125 VanDerWaalsContact C-N 3.34Å; V123-W125 PolarHBondContact O-N 3.24Å; W125-S129 WeakPolarHBondContact O-CB 3.4Å; W125-S129 PolarHBondContact O-N 3.39Å; W125-V132 HydrophobicContact CH2-CG1 4.18Å; W125-V132 HydrophobicContact CZ2-CB 4.18Å; W125-V132 HydrophobicContact CZ2-CG1 3.73Å; W125-I191 HydrophobicContact CH2-CG2 4.36Å; W125-F195 HydrophobicContact CE3-CD2 4.45Å; W125-F195 HydrophobicContact CH2-CB 4Å; W125-F195 AromaticContact CH2-CD2 3.98Å; W125-F195 HydrophobicContact CH2-CD2 3.98Å; W125-F195 HydrophobicContact CH2-CG 4.43Å; W125-F195 HydrophobicContact CZ2-CD2 4.38Å; W125-F195 HydrophobicContact CZ3-CB 3.67Å; W125-F195 HydrophobicContact CZ3-CD2 4.02Å; W125-F195 HydrophobicContact CZ3-CG 4.36Å; W125-V198 HydrophobicContact CB-CG1 4.13Å; W125-V198 HydrophobicContact CB-CG2 4.22Å; W125-V198 HydrophobicContact CE3-CG2 4.34Å; W125-F348 AromaticContact CH2-CE1 3.97Å; W125-F348 HydrophobicContact CH2-CE1 3.97Å; W125-F348 AromaticContact CH2-CZ 3.8Å; W125-F348 HydrophobicContact CH2-CZ 3.8Å; W125-F348 HydrophobicContact CZ2-CZ 4.24Å
126	R	86	Confident	88.5	Confident	55 Å²	55	53.7 Å²	53.7	21%	0.208	26%	0.257	C	S	.	.	H	α-helix	trans	-65.4	-39.8	-178.8	-68	-74	-70.6	-160.7	-13.5	112.4	L12 E20 H122 V123 L124 P133	L12-R126 HydrophobicContact CD1-CB 4.32Å; E20-R126 VanDerWaalsContact CD-CZ 3.41Å; E20-R126 VanDerWaalsContact CD-NH2 3.29Å; E20-R126 IonicContact OE1-CZ 2.61Å; E20-R126 IonicContact OE1-NH1 3.39Å; E20-R126 PolarHBondContact OE1-NH1 3.4Å; E20-R126 IonicContact OE1-NH2 2.6Å; E20-R126 PolarHBondContact OE1-NH2 3.46Å; E20-R126 IonicContact OE2-CZ 3.78Å; E20-R126 IonicContact OE2-NE 2.89Å; E20-R126 IonicContact OE2-NH1 2.71Å; E20-R126 PolarHBondContact OE2-NH1 3.25Å; E20-R126 IonicContact OE2-NH2 3.9Å; E20-R126 PolarHBondContact OE2-NH2 3.11Å; H122-R126 WeakPolarHBondContact O-CG 3.37Å; H122-R126 PolarHBondContact O-N 3.43Å; V123-R126 PolarHBondContact O-N 3.26Å; L124-R126 PolarHBondContact O-N 2.95Å; R126-P133 VanDerWaalsContact NH1-CB 3.29Å
127	V	87.5	Confident	88.1	Confident	77 Å²	77	52.2 Å²	52.2	47%	0.467	25%	0.246	S	C	.	.	H	α-helix	trans	-76.5	-43.7	-177.1	173.2	0	0	0	0	111.5	V123 L124 K130	V123-V127 HydrophobicContact CG1-CG2 4.09Å; V123-V127 WeakPolarHBondContact O-CB 3.42Å; V123-V127 VanDerWaalsContact O-CG2 3.3Å; V123-V127 WeakPolarHBondContact O-CG2 3.45Å; V123-V127 PolarHBondContact O-N 3.01Å; L124-V127 PolarHBondContact O-N 3.5Å; V127-K130 WeakPolarHBondContact O-CG 3.33Å
128	W	87.3	Confident	87.7	Confident	129 Å²	129	51.1 Å²	51.1	49%	0.489	24%	0.242	S	C	.	.	H	α-helix	trans	-80.6	-32.6	-176.6	-67.6	-21.7	0	0	0	113.4	L124 L194 F201	L124-W128 HydrophobicContact CB-CD2 4.47Å; L124-W128 HydrophobicContact CB-CE3 4.03Å; L124-W128 HydrophobicContact CB-CZ3 4.13Å; L124-W128 HydrophobicContact CD1-CH2 4.26Å; L124-W128 HydrophobicContact CD1-CZ3 4.29Å; L124-W128 HydrophobicContact CD2-CD2 4.41Å; L124-W128 HydrophobicContact CD2-CE3 4.47Å; L124-W128 HydrophobicContact CD2-CH2 3.9Å; L124-W128 HydrophobicContact CD2-CZ2 3.75Å; L124-W128 HydrophobicContact CD2-CZ3 4.26Å; L124-W128 HydrophobicContact CG-CH2 4.49Å; L124-W128 HydrophobicContact CG-CZ3 4.47Å; L124-W128 VanDerWaalsContact O-CB 3.29Å; L124-W128 WeakPolarHBondContact O-CB 3.34Å; L124-W128 PolarHBondContact O-N 3.41Å; W128-L194 HydrophobicContact CB-CD1 3.87Å; W128-L194 HydrophobicContact CB-CD2 3.7Å; W128-L194 HydrophobicContact CB-CG 4.31Å; W128-L194 HydrophobicContact CD2-CD1 4.02Å; W128-L194 HydrophobicContact CE3-CD1 3.42Å; W128-L194 VanDerWaalsContact CE3-CD1 3.42Å; W128-L194 HydrophobicContact CG-CD1 4.28Å; W128-L194 HydrophobicContact CZ3-CD1 4.18Å; W128-F201 HydrophobicContact CH2-CE2 4.29Å; W128-F201 HydrophobicContact CZ3-CE2 4.24Å
129	S	85.5	Confident	87.3	Confident	9 Å²	9	51.1 Å²	51.1	6%	0.063	24%	0.242	C	C	.	.			trans	-113.4	70.2	178.8	-164.4	0	0	0	0	110.5	W125 R131 V132 P133	W125-S129 WeakPolarHBondContact O-CB 3.4Å; W125-S129 PolarHBondContact O-N 3.39Å; S129-R131 VanDerWaalsContact C-N 3.35Å; S129-R131 PolarHBondContact O-N 2.8Å; S129-V132 WeakPolarHBondContact OG-CB 3.37Å; S129-V132 WeakPolarHBondContact OG-CG2 3.29Å; S129-P133 WeakPolarHBondContact O-CD 3.38Å; S129-P133 WeakPolarHBondContact O-CG 3.26Å
130	K	82.8	Confident	87	Confident	156 Å²	156	54.4 Å²	54.4	68%	0.678	25%	0.254	S	S	*	.	S	Bend	trans	-64.6	-35.3	-173.9	-63.9	-177	-178.9	177.3	0	114.1	V127	V127-K130 WeakPolarHBondContact O-CG 3.33Å
131	R	84.5	Confident	86.5	Confident	177 Å²	177	55.4 Å²	55.4	67%	0.668	25%	0.254	S	S	*	.	H	α-helix	trans	-77.1	-37.9	-174.1	-66.8	-173.9	-177.7	-179.2	1.4	112.8	S129 V134 L135 E163	S129-R131 VanDerWaalsContact C-N 3.35Å; S129-R131 PolarHBondContact O-N 2.8Å; R131-V134 PolarHBondContact O-N 2.86Å; R131-L135 PolarHBondContact O-N 3.3Å; R131-E163 IonicContact CZ-OE1 2.93Å; R131-E163 IonicContact NH1-OE1 3.34Å; R131-E163 PolarHBondContact NH1-OE1 3.48Å; R131-E163 IonicContact NH1-OE2 2.86Å; R131-E163 PolarHBondContact NH1-OE2 3.14Å
132	V	86.1	Confident	86	Confident	8 Å²	8	55.4 Å²	55.4	5%	0.048	25%	0.254	C	S	.	.	H	α-helix	trans	-66.7	-49.1	-170.9	178	0	0	0	0	112.8	W125 S129 V134 L135 L136 I191 F348	W125-V132 HydrophobicContact CH2-CG1 4.18Å; W125-V132 HydrophobicContact CZ2-CB 4.18Å; W125-V132 HydrophobicContact CZ2-CG1 3.73Å; S129-V132 WeakPolarHBondContact OG-CB 3.37Å; S129-V132 WeakPolarHBondContact OG-CG2 3.29Å; V132-V134 VanDerWaalsContact C-N 3.26Å; V132-V134 PolarHBondContact O-N 3.26Å; V132-L135 WeakPolarHBondContact O-CB 3.42Å; V132-L135 PolarHBondContact O-N 2.82Å; V132-L135 VanDerWaalsContact O-N 3.1Å; V132-L136 HydrophobicContact CG1-CD1 3.79Å; V132-L136 HydrophobicContact CG1-CG 4.06Å; V132-L136 VanDerWaalsContact O-CG 3.31Å; V132-L136 WeakPolarHBondContact O-CG 3.37Å; V132-L136 PolarHBondContact O-N 2.95Å; V132-I191 HydrophobicContact CG2-CD1 4.03Å; V132-I191 HydrophobicContact CG2-CG2 3.74Å; V132-F348 HydrophobicContact CG1-CE1 4.31Å
133	P	83.8	Confident	85.4	Confident	5 Å²	5	57.9 Å²	57.9	3%	0.032	28%	0.275	C	S	.	.	H	α-helix	trans	-59.8	-35.6	177.7	-23	33.5	0	0	0	113	R126 S129 K137	R126-P133 VanDerWaalsContact NH1-CB 3.29Å; S129-P133 WeakPolarHBondContact O-CD 3.38Å; S129-P133 WeakPolarHBondContact O-CG 3.26Å; P133-K137 VanDerWaalsContact O-CB 3.27Å; P133-K137 WeakPolarHBondContact O-CB 3.45Å; P133-K137 PolarHBondContact O-N 3.34Å
134	V	84.8	Confident	84.8	Confident	83 Å²	83	60.4 Å²	60.4	50%	0.503	29%	0.291	S	S	.	.	H	α-helix	trans	-65.7	-44.8	175.2	177.9	0	0	0	0	110.4	R131 V132 K137 N138	R131-V134 PolarHBondContact O-N 2.86Å; V132-V134 VanDerWaalsContact C-N 3.26Å; V132-V134 PolarHBondContact O-N 3.26Å; V134-K137 WeakPolarHBondContact O-CB 3.41Å; V134-K137 PolarHBondContact O-N 2.92Å; V134-N138 VanDerWaalsContact O-CG 3.28Å; V134-N138 PolarHBondContact O-N 2.95Å; V134-N138 PolarHBondContact O-OD1 2.98Å
135	L	85.6	Confident	84.1	Confident	19 Å²	19	65.1 Å²	65.1	10%	0.099	32%	0.324	C	S	.	.	H	α-helix	trans	-63.8	-42.9	178.2	-173.2	57.4	0	0	0	112.2	R131 V132 K137 N138 A139 L157 A160 L349	R131-L135 PolarHBondContact O-N 3.3Å; V132-L135 WeakPolarHBondContact O-CB 3.42Å; V132-L135 PolarHBondContact O-N 2.82Å; V132-L135 VanDerWaalsContact O-N 3.1Å; L135-K137 VanDerWaalsContact C-N 3.34Å; L135-N138 PolarHBondContact O-N 3.26Å; L135-A139 WeakPolarHBondContact O-CB 3.22Å; L135-A139 PolarHBondContact O-N 2.83Å; L135-L157 HydrophobicContact CD1-CD2 3.62Å; L135-L157 HydrophobicContact CD1-CG 3.98Å; L135-L157 HydrophobicContact CD2-CD2 3.9Å; L135-L157 HydrophobicContact CG-CD2 3.55Å; L135-L157 HydrophobicContact CG-CG 4.44Å; L135-A160 HydrophobicContact CD2-CB 3.7Å; L135-L349 HydrophobicContact CD2-CD1 3.84Å; L135-L349 HydrophobicContact CD2-CD2 3.5Å; L135-L349 VanDerWaalsContact CD2-CD2 3.5Å; L135-L349 HydrophobicContact CD2-CG 4.28Å; L135-L349 HydrophobicContact CG-CD1 4.39Å
136	L	86.2	Confident	83.7	Confident	5 Å²	5	68.6 Å²	68.6	3%	0.026	34%	0.343	C	S	.	.	H	α-helix	trans	-66.7	-35.3	176.4	-65.9	179.3	0	0	0	112.1	V22 V132 A139 R140 L349 A352 V353 I356	V22-L136 HydrophobicContact CG2-CD1 3.88Å; V132-L136 HydrophobicContact CG1-CD1 3.79Å; V132-L136 HydrophobicContact CG1-CG 4.06Å; V132-L136 VanDerWaalsContact O-CG 3.31Å; V132-L136 WeakPolarHBondContact O-CG 3.37Å; V132-L136 PolarHBondContact O-N 2.95Å; L136-A139 PolarHBondContact O-N 3.39Å; L136-R140 WeakPolarHBondContact O-CB 3.5Å; L136-R140 PolarHBondContact O-N 2.99Å; L136-L349 HydrophobicContact CD2-CD1 3.91Å; L136-A352 HydrophobicContact CD1-CB 4.29Å; L136-A352 HydrophobicContact CD2-CB 3.82Å; L136-V353 HydrophobicContact CD2-CG2 3.75Å; L136-I356 HydrophobicContact CB-CD1 3.84Å; L136-I356 HydrophobicContact CD1-CD1 3.82Å; L136-I356 HydrophobicContact CD2-CD1 4.05Å; L136-I356 HydrophobicContact CG-CD1 4.1Å
137	K	85.1	Confident	83.6	Confident	104 Å²	104	73.4 Å²	73.4	45%	0.452	37%	0.365	S	S	.	.	H	α-helix	trans	-63.2	-48.7	173.6	-177.4	-178	172.8	-175.9	0	111.3	P133 V134 L135 A139 R140 E141	P133-K137 VanDerWaalsContact O-CB 3.27Å; P133-K137 WeakPolarHBondContact O-CB 3.45Å; P133-K137 PolarHBondContact O-N 3.34Å; V134-K137 WeakPolarHBondContact O-CB 3.41Å; V134-K137 PolarHBondContact O-N 2.92Å; L135-K137 VanDerWaalsContact C-N 3.34Å; K137-A139 VanDerWaalsContact C-N 3.28Å; K137-A139 PolarHBondContact O-N 3.34Å; K137-R140 WeakPolarHBondContact O-CB 3.19Å; K137-R140 PolarHBondContact O-N 3.24Å; K137-R140 VanDerWaalsContact O-N 3.13Å; K137-E141 WeakPolarHBondContact CE-OE1 3.46Å; K137-E141 IonicContact NZ-OE1 2.69Å; K137-E141 PolarHBondContact O-N 3.21Å
138	N	85.3	Confident	83.6	Confident	56 Å²	56	77.2 Å²	77.2	30%	0.299	38%	0.378	S	S	.	.	H	α-helix	trans	-60.6	-40.2	176.9	-64.5	-7.3	0	0	0	111.4	V134 L135 R140 E141 A142	V134-N138 VanDerWaalsContact O-CG 3.28Å; V134-N138 PolarHBondContact O-N 2.95Å; V134-N138 PolarHBondContact O-OD1 2.98Å; L135-N138 PolarHBondContact O-N 3.26Å; N138-R140 VanDerWaalsContact C-N 3.32Å; N138-R140 PolarHBondContact O-N 3.43Å; N138-E141 PolarHBondContact O-N 3.03Å; N138-A142 PolarHBondContact O-N 3.31Å; N138-A142 VanDerWaalsContact O-N 3.11Å
139	A	85.5	Confident	83.6	Confident	1 Å²	1	73.8 Å²	73.8	1%	0.008	37%	0.371	C	S	.	.	H	α-helix	trans	-64.2	-36.2	176.2	0	0	0	0	0	112.6	L135 L136 K137 A142 L157 V353 S357	L135-A139 WeakPolarHBondContact O-CB 3.22Å; L135-A139 PolarHBondContact O-N 2.83Å; L136-A139 PolarHBondContact O-N 3.39Å; K137-A139 VanDerWaalsContact C-N 3.28Å; K137-A139 PolarHBondContact O-N 3.34Å; A139-A142 PolarHBondContact O-N 2.89Å; A139-L157 HydrophobicContact CB-CD1 3.99Å; A139-V353 HydrophobicContact CB-CG1 4.15Å; A139-V353 HydrophobicContact CB-CG2 4.15Å; A139-S357 VanDerWaalsContact O-CB 3.28Å; A139-S357 WeakPolarHBondContact O-CB 3.04Å
140	R	84.8	Confident	83.6	Confident	92 Å²	92	77.2 Å²	77.2	35%	0.347	38%	0.383	S	S	.	.	H	α-helix	trans	-67.8	-44.9	175.3	-169.3	178.8	173.4	-179.4	-2.7	112.3	Y17 G18 G19 L136 K137 N138 A142 A143 I356	Y17-R140 PolarHBondContact O-NH2 2.85Å; G18-R140 VanDerWaalsContact C-NH1 3.26Å; G18-R140 PolarHBondContact O-NH1 3.27Å; G18-R140 PolarHBondContact O-NH2 2.94Å; G19-R140 PolarHBondContact O-NH1 3.04Å; L136-R140 WeakPolarHBondContact O-CB 3.5Å; L136-R140 PolarHBondContact O-N 2.99Å; K137-R140 WeakPolarHBondContact O-CB 3.19Å; K137-R140 PolarHBondContact O-N 3.24Å; K137-R140 VanDerWaalsContact O-N 3.13Å; N138-R140 VanDerWaalsContact C-N 3.32Å; N138-R140 PolarHBondContact O-N 3.43Å; R140-A142 PolarHBondContact O-N 2.88Å; R140-A143 VanDerWaalsContact O-CB 3.25Å; R140-A143 WeakPolarHBondContact O-CB 3.49Å; R140-A143 PolarHBondContact O-N 3.27Å; R140-I356 HydrophobicContact CB-CG2 3.58Å; R140-I356 HydrophobicContact CG-CG2 3.77Å
141	E	82.8	Confident	83.9	Confident	96 Å²	96	74.6 Å²	74.6	45%	0.449	37%	0.373	S	S	.	.	H	α-helix	trans	-62.6	-31.5	178.1	-71.4	173.3	-175	0	0	111.4	K137 N138 A143 V144	K137-E141 WeakPolarHBondContact CE-OE1 3.46Å; K137-E141 IonicContact NZ-OE1 2.69Å; K137-E141 PolarHBondContact O-N 3.21Å; N138-E141 PolarHBondContact O-N 3.03Å; E141-A143 PolarHBondContact O-N 3.44Å; E141-V144 WeakPolarHBondContact O-CB 3.38Å; E141-V144 WeakPolarHBondContact O-CG2 3.49Å; E141-V144 PolarHBondContact O-N 3.01Å
142	A	82.5	Confident	84.2	Confident	3 Å²	3	73.6 Å²	73.6	3%	0.025	37%	0.373	C	S	.	.	T	Hydrogen-bonded Turn	trans	-70.9	-6.1	173.4	0	0	0	0	0	115.7	N138 A139 R140 A153 I361	N138-A142 PolarHBondContact O-N 3.31Å; N138-A142 VanDerWaalsContact O-N 3.11Å; A139-A142 PolarHBondContact O-N 2.89Å; R140-A142 PolarHBondContact O-N 2.88Å; A142-A153 HydrophobicContact CB-CB 3.32Å; A142-I361 HydrophobicContact CB-CD1 4.04Å
143	A	76.5	Confident	84.3	Confident	55 Å²	55	73.5 Å²	73.5	46%	0.455	37%	0.373	S	S	.	.	T	Hydrogen-bonded Turn	trans	-74.3	-16.6	170.4	0	0	0	0	0	112.4	R140 E141	R140-A143 VanDerWaalsContact O-CB 3.25Å; R140-A143 WeakPolarHBondContact O-CB 3.49Å; R140-A143 PolarHBondContact O-N 3.27Å; E141-A143 PolarHBondContact O-N 3.44Å
144	V	78.4	Confident	84.5	Confident	92 Å²	92	73.5 Å²	73.5	56%	0.558	37%	0.373	S	S	*	.	S	Bend	trans	-73	145	174.2	-178.8	0	0	0	0	109.2	E141 D146	E141-V144 WeakPolarHBondContact O-CB 3.38Å; E141-V144 WeakPolarHBondContact O-CG2 3.49Å; E141-V144 PolarHBondContact O-N 3.01Å; V144-D146 PolarHBondContact O-N 2.95Å
145	P	74.5	Confident	84.9	Confident	139 Å²	139	72.6 Å²	72.6	90%	0.903	37%	0.37	S	S	*	.	S	Bend	trans	-70.5	38.5	-171.4	28.3	-37.7	0	0	0	116.3
146	D	82.1	Confident	85.1	Confident	80 Å²	80	74.2 Å²	74.2	43%	0.428	38%	0.383	S	S	.	.			trans	-99.8	119.3	171.5	-169.7	-22.7	0	0	0	111	V144 E148 V149 R150	V144-D146 PolarHBondContact O-N 2.95Å; D146-E148 PolarHBondContact O-N 3.46Å; D146-E148 PolarHBondContact OD1-N 2.81Å; D146-V149 HydrophobicContact CB-CB 4.12Å; D146-V149 HydrophobicContact CB-CG2 4Å; D146-R150 WeakPolarHBondContact O-CB 3.27Å; D146-R150 PolarHBondContact O-N 3.03Å
147	K	84.5	Confident	85.4	Confident	155 Å²	155	74.2 Å²	74.2	67%	0.674	38%	0.383	S	S	*	.	H	α-helix	trans	-65.6	-37.7	-177.6	-171.2	179.2	178.8	-175.3	0	112.2	H151	K147-H151 WeakPolarHBondContact CE-NE2 3.35Å; K147-H151 PolarHBondContact O-CD2 3.35Å; K147-H151 PolarHBondContact O-N 3.39Å
148	E	87.4	Confident	85.7	Confident	157 Å²	157	69.5 Å²	69.5	73%	0.734	36%	0.363	S	S	*	.	H	α-helix	trans	-71.5	-46.1	-176.8	-172.2	176.3	168.8	0	0	110.9	D146 R150 H151 K152	D146-E148 PolarHBondContact O-N 3.46Å; D146-E148 PolarHBondContact OD1-N 2.81Å; E148-R150 VanDerWaalsContact C-N 3.3Å; E148-R150 PolarHBondContact O-N 3.27Å; E148-H151 PolarHBondContact O-N 3.21Å; E148-K152 WeakPolarHBondContact O-CB 3.41Å; E148-K152 PolarHBondContact O-N 2.81Å
149	V	86.3	Confident	86	Confident	57 Å²	57	69.5 Å²	69.5	35%	0.345	37%	0.37	S	S	.	.	H	α-helix	trans	-60.2	-42.4	175.7	179.5	0	0	0	0	110.6	D146 K152 A153	D146-V149 HydrophobicContact CB-CB 4.12Å; D146-V149 HydrophobicContact CB-CG2 4Å; V149-K152 PolarHBondContact O-N 3.02Å; V149-A153 WeakPolarHBondContact O-CB 3.5Å; V149-A153 PolarHBondContact O-N 2.89Å
150	R	87.3	Confident	86.3	Confident	82 Å²	82	70.5 Å²	70.5	31%	0.309	38%	0.378	S	S	.	.	H	α-helix	trans	-61.5	-48.9	177.3	-165.7	-177.5	104.9	-173.8	13.1	112.4	D146 E148 K152 A153 I154 D364	D146-R150 WeakPolarHBondContact O-CB 3.27Å; D146-R150 PolarHBondContact O-N 3.03Å; E148-R150 VanDerWaalsContact C-N 3.3Å; E148-R150 PolarHBondContact O-N 3.27Å; R150-K152 VanDerWaalsContact C-N 3.31Å; R150-K152 PolarHBondContact O-N 3.23Å; R150-A153 PolarHBondContact O-N 3.41Å; R150-I154 HydrophobicContact CG-CD1 3.9Å; R150-I154 WeakPolarHBondContact O-CB 3.38Å; R150-I154 VanDerWaalsContact O-CG1 3.3Å; R150-I154 WeakPolarHBondContact O-CG1 3.19Å; R150-I154 PolarHBondContact O-N 3.3Å; R150-D364 IonicContact CZ-OD2 3.73Å; R150-D364 IonicContact NE-OD2 3.87Å; R150-D364 IonicContact NH2-OD2 2.94Å; R150-D364 PolarHBondContact NH2-OD2 3.39Å
151	H	88.9	Confident	86.6	Confident	100 Å²	100	66.2 Å²	66.2	46%	0.463	36%	0.362	S	S	.	.	H	α-helix	trans	-61.1	-40.1	178	-79.2	-56.4	0	0	0	112.2	K147 E148 I154 S155	K147-H151 WeakPolarHBondContact CE-NE2 3.35Å; K147-H151 PolarHBondContact O-CD2 3.35Å; K147-H151 PolarHBondContact O-N 3.39Å; E148-H151 PolarHBondContact O-N 3.21Å; H151-I154 PolarHBondContact O-N 2.89Å; H151-S155 WeakPolarHBondContact O-CB 3.44Å; H151-S155 PolarHBondContact O-N 3.48Å; H151-S155 PolarHBondContact O-OG 3.5Å
152	K	89.1	Confident	86.9	Confident	156 Å²	156	64.6 Å²	64.6	68%	0.678	36%	0.355	S	S	*	.	H	α-helix	trans	-65.8	-39.7	177	-172.2	177.3	-177.7	176.5	0	112.8	E148 V149 R150 S155 C156	E148-K152 WeakPolarHBondContact O-CB 3.41Å; E148-K152 PolarHBondContact O-N 2.81Å; V149-K152 PolarHBondContact O-N 3.02Å; R150-K152 VanDerWaalsContact C-N 3.31Å; R150-K152 PolarHBondContact O-N 3.23Å; K152-S155 PolarHBondContact O-OG 2.99Å; K152-C156 VanDerWaalsContact O-CB 3.26Å; K152-C156 WeakPolarHBondContact O-CB 3.21Å; K152-C156 PolarHBondContact O-N 3.11Å
153	A	88.2	Confident	87.3	Confident	6 Å²	6	69.4 Å²	69.4	5%	0.05	38%	0.377	C	S	.	.	H	α-helix	trans	-69	-42.5	176.5	0	0	0	0	0	111.9	A142 V149 R150 C156 L157	A142-A153 HydrophobicContact CB-CB 3.32Å; V149-A153 WeakPolarHBondContact O-CB 3.5Å; V149-A153 PolarHBondContact O-N 2.89Å; R150-A153 PolarHBondContact O-N 3.41Å; A153-C156 PolarHBondContact O-N 3.38Å; A153-L157 WeakPolarHBondContact O-CB 3.31Å; A153-L157 VanDerWaalsContact O-CG 3.31Å; A153-L157 WeakPolarHBondContact O-CG 3.29Å; A153-L157 PolarHBondContact O-N 3.29Å
154	I	90	Very high	87.8	Confident	6 Å²	6	68.1 Å²	68.1	3%	0.031	36%	0.362	C	S	.	.	H	α-helix	trans	-60.7	-47.5	175.4	-69.8	168.6	0	0	0	110.4	R150 H151 C156 L157 V158 I361 D364 V365 M368	R150-I154 HydrophobicContact CG-CD1 3.9Å; R150-I154 WeakPolarHBondContact O-CB 3.38Å; R150-I154 VanDerWaalsContact O-CG1 3.3Å; R150-I154 WeakPolarHBondContact O-CG1 3.19Å; R150-I154 PolarHBondContact O-N 3.3Å; H151-I154 PolarHBondContact O-N 2.89Å; I154-C156 VanDerWaalsContact C-N 3.33Å; I154-C156 PolarHBondContact O-N 2.85Å; I154-L157 PolarHBondContact O-N 3.49Å; I154-V158 HydrophobicContact CG2-CG2 4.3Å; I154-V158 WeakPolarHBondContact O-CB 3.43Å; I154-V158 VanDerWaalsContact O-CG2 3.26Å; I154-V158 WeakPolarHBondContact O-CG2 3.21Å; I154-V158 PolarHBondContact O-N 3.48Å; I154-I361 HydrophobicContact CG1-CG2 4.13Å; I154-D364 HydrophobicContact CD1-CB 3.97Å; I154-V365 HydrophobicContact CB-CG2 4.4Å; I154-V365 HydrophobicContact CG1-CG2 4.29Å; I154-V365 HydrophobicContact CG2-CG2 3.94Å; I154-M368 HydrophobicContact CG2-CE 4.37Å; I154-M368 HydrophobicContact CG2-SD 3.55Å; I154-M368 VanDerWaalsContact CG2-SD 3.55Å
155	S	91.2	Very high	88.1	Confident	64 Å²	64	64.5 Å²	64.5	45%	0.448	34%	0.341	S	S	.	.	H	α-helix	trans	-63.9	-38.7	179.1	65.5	0	0	0	0	112.3	H151 K152 A159	H151-S155 WeakPolarHBondContact O-CB 3.44Å; H151-S155 PolarHBondContact O-N 3.48Å; H151-S155 PolarHBondContact O-OG 3.5Å; K152-S155 PolarHBondContact O-OG 2.99Å; S155-A159 VanDerWaalsContact O-CB 3.29Å; S155-A159 WeakPolarHBondContact O-CB 3.33Å; S155-A159 PolarHBondContact O-N 3.42Å
156	C	90.9	Very high	88.6	Confident	53 Å²	53	63.1 Å²	63.1	36%	0.358	32%	0.322	S	S	.	.	H	α-helix	trans	-65	-42.4	174.5	-173	0	0	0	0	112.4	K152 A153 I154 A160	K152-C156 VanDerWaalsContact O-CB 3.26Å; K152-C156 WeakPolarHBondContact O-CB 3.21Å; K152-C156 PolarHBondContact O-N 3.11Å; A153-C156 PolarHBondContact O-N 3.38Å; I154-C156 VanDerWaalsContact C-N 3.33Å; I154-C156 PolarHBondContact O-N 2.85Å; C156-A160 WeakPolarHBondContact O-CB 3.37Å; C156-A160 PolarHBondContact O-N 2.7Å
157	L	91.5	Very high	88.7	Confident	4 Å²	4	61.2 Å²	61.2	2%	0.021	32%	0.318	C	S	.	.	H	α-helix	trans	-63.8	-45.7	175.8	-78.8	167.9	0	0	0	112	L135 A139 A153 I154 A160 L161 L349 V353 I361 V365	L135-L157 HydrophobicContact CD1-CD2 3.62Å; L135-L157 HydrophobicContact CD1-CG 3.98Å; L135-L157 HydrophobicContact CD2-CD2 3.9Å; L135-L157 HydrophobicContact CG-CD2 3.55Å; L135-L157 HydrophobicContact CG-CG 4.44Å; A139-L157 HydrophobicContact CB-CD1 3.99Å; A153-L157 WeakPolarHBondContact O-CB 3.31Å; A153-L157 VanDerWaalsContact O-CG 3.31Å; A153-L157 WeakPolarHBondContact O-CG 3.29Å; A153-L157 PolarHBondContact O-N 3.29Å; I154-L157 PolarHBondContact O-N 3.49Å; L157-A160 PolarHBondContact O-N 2.87Å; L157-L161 WeakPolarHBondContact O-CB 3.32Å; L157-L161 WeakPolarHBondContact O-CG 3.17Å; L157-L161 PolarHBondContact O-N 2.74Å; L157-L349 HydrophobicContact CD2-CD2 4.47Å; L157-V353 HydrophobicContact CD1-CG1 4.17Å; L157-V353 HydrophobicContact CD1-CG2 4.37Å; L157-V353 HydrophobicContact CD2-CG2 3.77Å; L157-I361 HydrophobicContact CD1-CG2 3.97Å; L157-V365 HydrophobicContact CB-CG2 4.17Å; L157-V365 HydrophobicContact CD1-CG2 4.23Å
158	V	92.5	Very high	88.6	Confident	6 Å²	6	54.2 Å²	54.2	4%	0.036	29%	0.289	C	S	.	.	H	α-helix	trans	-62.4	-47.4	177.6	170.6	0	0	0	0	110.2	I154 A160 L161 E162 V365 M368 L369	I154-V158 HydrophobicContact CG2-CG2 4.3Å; I154-V158 WeakPolarHBondContact O-CB 3.43Å; I154-V158 VanDerWaalsContact O-CG2 3.26Å; I154-V158 WeakPolarHBondContact O-CG2 3.21Å; I154-V158 PolarHBondContact O-N 3.48Å; V158-A160 VanDerWaalsContact C-N 3.33Å; V158-A160 PolarHBondContact O-N 2.89Å; V158-L161 PolarHBondContact O-N 3.34Å; V158-L161 VanDerWaalsContact O-N 3.16Å; V158-E162 HydrophobicContact CG1-CG 4.32Å; V158-E162 WeakPolarHBondContact O-CB 3.38Å; V158-E162 WeakPolarHBondContact O-CG 3.25Å; V158-E162 PolarHBondContact O-N 3.4Å; V158-V365 HydrophobicContact CG2-CB 4.35Å; V158-V365 HydrophobicContact CG2-CG1 3.91Å; V158-V365 HydrophobicContact CG2-CG2 4.26Å; V158-M368 HydrophobicContact CB-CE 4.28Å; V158-M368 HydrophobicContact CG1-CE 4.17Å; V158-M368 HydrophobicContact CG2-CB 4.22Å; V158-M368 HydrophobicContact CG2-CE 3.81Å; V158-M368 HydrophobicContact CG2-SD 4.26Å; V158-L369 HydrophobicContact CG1-CD2 4.04Å
159	A	92.1	Very high	88.3	Confident	55 Å²	55	51.3 Å²	51.3	46%	0.455	27%	0.274	S	S	.	.	H	α-helix	trans	-59.5	-41.7	177	0	0	0	0	0	112.5	S155 E162 E163	S155-A159 VanDerWaalsContact O-CB 3.29Å; S155-A159 WeakPolarHBondContact O-CB 3.33Å; S155-A159 PolarHBondContact O-N 3.42Å; A159-E162 PolarHBondContact O-N 2.93Å; A159-E163 PolarHBondContact O-N 2.91Å
160	A	90.3	Very high	88.1	Confident	22 Å²	22	57 Å²	57	18%	0.182	29%	0.289	C	S	.	.	H	α-helix	trans	-64.9	-39.5	176.3	0	0	0	0	0	112.5	L135 C156 L157 V158 I164	L135-A160 HydrophobicContact CD2-CB 3.7Å; C156-A160 WeakPolarHBondContact O-CB 3.37Å; C156-A160 PolarHBondContact O-N 2.7Å; L157-A160 PolarHBondContact O-N 2.87Å; V158-A160 VanDerWaalsContact C-N 3.33Å; V158-A160 PolarHBondContact O-N 2.89Å; A160-I164 VanDerWaalsContact O-CG1 3.3Å; A160-I164 WeakPolarHBondContact O-CG1 2.92Å; A160-I164 PolarHBondContact O-N 3.12Å
161	L	91	Very high	87.5	Confident	2 Å²	2	55.2 Å²	55.2	1%	0.01	28%	0.282	C	S	.	.	H	α-helix	trans	-70.9	-36.1	177.1	-73.5	170	0	0	0	112.1	L157 V158 I164 S165 L342 G346 L349 L350 V365 L369	L157-L161 WeakPolarHBondContact O-CB 3.32Å; L157-L161 WeakPolarHBondContact O-CG 3.17Å; L157-L161 PolarHBondContact O-N 2.74Å; V158-L161 PolarHBondContact O-N 3.34Å; V158-L161 VanDerWaalsContact O-N 3.16Å; L161-I164 HydrophobicContact CD2-CD1 4.48Å; L161-I164 PolarHBondContact O-N 2.96Å; L161-S165 WeakPolarHBondContact O-CB 3.35Å; L161-S165 PolarHBondContact O-N 3.29Å; L161-L342 HydrophobicContact CD2-CD1 3.88Å; L161-G346 VanDerWaalsContact CD2-CA 3.42Å; L161-L349 HydrophobicContact CD2-CB 4.28Å; L161-L349 HydrophobicContact CD2-CD2 3.75Å; L161-L349 HydrophobicContact CD2-CG 4.42Å; L161-L349 HydrophobicContact CG-CD2 3.97Å; L161-L350 HydrophobicContact CD1-CD2 3.66Å; L161-L350 HydrophobicContact CD1-CG 4.05Å; L161-V365 HydrophobicContact CD1-CG1 3.72Å; L161-L369 HydrophobicContact CB-CD1 4.04Å; L161-L369 HydrophobicContact CB-CD2 4.13Å; L161-L369 HydrophobicContact CD1-CD1 3.57Å; L161-L369 HydrophobicContact CG-CD1 4.4Å
162	E	90.6	Very high	86.9	Confident	62 Å²	62	55 Å²	55	29%	0.29	28%	0.278	S	S	.	.	H	α-helix	trans	-65.9	-43.6	173.8	-74.5	179.3	167.6	0	0	111.3	V158 A159 I164 S165 E166 L369 N372	V158-E162 HydrophobicContact CG1-CG 4.32Å; V158-E162 WeakPolarHBondContact O-CB 3.38Å; V158-E162 WeakPolarHBondContact O-CG 3.25Å; V158-E162 PolarHBondContact O-N 3.4Å; A159-E162 PolarHBondContact O-N 2.93Å; E162-I164 VanDerWaalsContact C-N 3.31Å; E162-I164 PolarHBondContact O-N 2.88Å; E162-S165 CarbonylContact O-C 3.58Å; E162-S165 WeakPolarHBondContact O-CA 3.47Å; E162-S165 WeakPolarHBondContact O-CB 3.21Å; E162-S165 PolarHBondContact O-N 3Å; E162-S165 PolarHBondContact O-OG 3.46Å; E162-E166 WeakPolarHBondContact O-CG 3.41Å; E162-E166 PolarHBondContact O-N 3.3Å; E162-L369 HydrophobicContact CG-CD2 3.9Å; E162-N372 PolarHBondContact OE1-ND2 3.42Å
163	E	89.2	Confident	86.3	Confident	105 Å²	105	58.8 Å²	58.8	49%	0.491	29%	0.287	S	S	.	.	H	α-helix	trans	-56	-44.4	173.4	-172.7	-173	173.7	0	0	111.2	R131 A159 S165 E166 A167	R131-E163 IonicContact CZ-OE1 2.93Å; R131-E163 IonicContact NH1-OE1 3.34Å; R131-E163 PolarHBondContact NH1-OE1 3.48Å; R131-E163 IonicContact NH1-OE2 2.86Å; R131-E163 PolarHBondContact NH1-OE2 3.14Å; A159-E163 PolarHBondContact O-N 2.91Å; E163-S165 VanDerWaalsContact C-N 3.34Å; E163-S165 PolarHBondContact O-N 3.01Å; E163-E166 PolarHBondContact O-N 2.75Å; E163-A167 WeakPolarHBondContact O-CB 3.43Å; E163-A167 PolarHBondContact O-N 3.47Å
164	I	86.9	Confident	85.7	Confident	28 Å²	28	63.7 Å²	63.7	14%	0.144	32%	0.317	C	S	.	.	H	α-helix	trans	-62.1	-42.6	174.9	-67.8	165.4	0	0	0	110.7	A160 L161 E162 A167 S168 T188 D345	A160-I164 VanDerWaalsContact O-CG1 3.3Å; A160-I164 WeakPolarHBondContact O-CG1 2.92Å; A160-I164 PolarHBondContact O-N 3.12Å; L161-I164 HydrophobicContact CD2-CD1 4.48Å; L161-I164 PolarHBondContact O-N 2.96Å; E162-I164 VanDerWaalsContact C-N 3.31Å; E162-I164 PolarHBondContact O-N 2.88Å; I164-A167 PolarHBondContact O-N 2.96Å; I164-S168 PolarHBondContact O-N 2.97Å; I164-T188 HydrophobicContact CG2-CG2 4.08Å; I164-D345 HydrophobicContact CD1-CB 4.5Å; I164-D345 HydrophobicContact CG2-CB 4.3Å
165	S	85.7	Confident	84.5	Confident	16 Å²	16	66.9 Å²	66.9	11%	0.112	33%	0.329	C	S	.	.	H	α-helix	trans	-67.1	-38.8	-179.5	86.3	0	0	0	0	112.7	L161 E162 E163 S168 K169 N341	L161-S165 WeakPolarHBondContact O-CB 3.35Å; L161-S165 PolarHBondContact O-N 3.29Å; E162-S165 CarbonylContact O-C 3.58Å; E162-S165 WeakPolarHBondContact O-CA 3.47Å; E162-S165 WeakPolarHBondContact O-CB 3.21Å; E162-S165 PolarHBondContact O-N 3Å; E162-S165 PolarHBondContact O-OG 3.46Å; E163-S165 VanDerWaalsContact C-N 3.34Å; E163-S165 PolarHBondContact O-N 3.01Å; S165-S168 VanDerWaalsContact O-CB 3.24Å; S165-S168 WeakPolarHBondContact O-CB 3.37Å; S165-S168 PolarHBondContact O-N 3.4Å; S165-K169 WeakPolarHBondContact O-CG 3.14Å; S165-K169 PolarHBondContact O-N 2.95Å; S165-N341 VanDerWaalsContact CA-O 3.26Å; S165-N341 WeakPolarHBondContact CA-O 3.35Å; S165-N341 VanDerWaalsContact CB-O 3.28Å; S165-N341 WeakPolarHBondContact CB-O 3.19Å
166	E	85.8	Confident	83.4	Confident	109 Å²	109	66 Å²	66	51%	0.509	33%	0.33	S	S	.	.	H	α-helix	trans	-68.6	-41.4	176.3	-73	-175.2	-179.9	0	0	111.3	E162 E163 S168 K169 R170	E162-E166 WeakPolarHBondContact O-CG 3.41Å; E162-E166 PolarHBondContact O-N 3.3Å; E163-E166 PolarHBondContact O-N 2.75Å; E166-S168 VanDerWaalsContact C-N 3.27Å; E166-S168 PolarHBondContact O-N 2.98Å; E166-K169 PolarHBondContact O-N 3.39Å; E166-R170 WeakPolarHBondContact O-CB 3.33Å; E166-R170 PolarHBondContact O-N 3.17Å
167	A	83.6	Confident	82.2	Confident	41 Å²	41	70 Å²	70	34%	0.339	35%	0.346	S	S	.	.	H	α-helix	trans	-59.5	-39.5	173.2	0	0	0	0	0	111.6	E163 I164 R170 Y171	E163-A167 WeakPolarHBondContact O-CB 3.43Å; E163-A167 PolarHBondContact O-N 3.47Å; I164-A167 PolarHBondContact O-N 2.96Å; A167-R170 PolarHBondContact O-N 3.45Å; A167-Y171 WeakPolarHBondContact O-CB 3.37Å; A167-Y171 PolarHBondContact O-N 2.86Å
168	S	81.3	Confident	80.7	Confident	8 Å²	8	77.7 Å²	77.7	6%	0.056	38%	0.38	C	S	.	.	H	α-helix	trans	-59	-49.8	173	-167	0	0	0	0	112.3	I164 S165 E166 Y171 R172 T188 N340	I164-S168 PolarHBondContact O-N 2.97Å; S165-S168 VanDerWaalsContact O-CB 3.24Å; S165-S168 WeakPolarHBondContact O-CB 3.37Å; S165-S168 PolarHBondContact O-N 3.4Å; E166-S168 VanDerWaalsContact C-N 3.27Å; E166-S168 PolarHBondContact O-N 2.98Å; S168-Y171 PolarHBondContact O-N 3.46Å; S168-R172 WeakPolarHBondContact O-CB 3.32Å; S168-R172 PolarHBondContact O-N 2.96Å; S168-T188 WeakPolarHBondContact OG-CG2 3.44Å; S168-N340 PolarHBondContact OG-O 3.28Å
169	K	82.2	Confident	79.2	Confident	96 Å²	96	82.5 Å²	82.5	42%	0.417	40%	0.402	S	S	.	.	H	α-helix	trans	-62.7	-44.1	179.8	-70.8	172.9	-174.6	172.4	0	110.9	S165 E166 R172 R173 N341	S165-K169 WeakPolarHBondContact O-CG 3.14Å; S165-K169 PolarHBondContact O-N 2.95Å; E166-K169 PolarHBondContact O-N 3.39Å; K169-R172 PolarHBondContact O-N 3.02Å; K169-R173 PolarHBondContact O-N 3.22Å; K169-N341 WeakPolarHBondContact CE-OD1 3.5Å
170	R	81	Confident	77.6	Confident	175 Å²	175	84.8 Å²	84.8	66%	0.66	40%	0.399	S	S	*	.	H	α-helix	trans	-62	-47.8	178.4	-157.8	-179	-62.6	178.4	2.2	111	E166 A167 R172 R173 T174	E166-R170 WeakPolarHBondContact O-CB 3.33Å; E166-R170 PolarHBondContact O-N 3.17Å; A167-R170 PolarHBondContact O-N 3.45Å; R170-R172 VanDerWaalsContact C-N 3.31Å; R170-R172 PolarHBondContact O-N 3.14Å; R170-R173 PolarHBondContact O-N 3.36Å; R170-T174 PolarHBondContact O-N 3.47Å; R170-T174 PolarHBondContact O-OG1 3.07Å; R170-T174 VanDerWaalsContact O-OG1 3.06Å
171	Y	76	Confident	76	Confident	46 Å²	46	89.2 Å²	89.2	18%	0.18	43%	0.427	C	S	.	.	H	α-helix	trans	-57	-43.5	175.6	-179.2	-100.7	0	0	0	112.6	A167 S168 R175 G184 P186 P187	A167-Y171 WeakPolarHBondContact O-CB 3.37Å; A167-Y171 PolarHBondContact O-N 2.86Å; S168-Y171 PolarHBondContact O-N 3.46Å; Y171-R175 PolarHBondContact O-N 3.07Å; Y171-R175 PolarHBondContact OH-NH1 3.1Å; Y171-G184 PolarHBondContact OH-O 2.94Å; Y171-G184 VanDerWaalsContact OH-O 3.08Å; Y171-P186 HydrophobicContact CD1-CB 3.95Å; Y171-P186 HydrophobicContact CE1-CB 3.74Å; Y171-P187 VanDerWaalsContact CD2-CD 3.4Å; Y171-P187 HydrophobicContact CD2-CG 4.07Å; Y171-P187 HydrophobicContact CG-CG 3.9Å
172	R	76	Confident	74.4	Confident	96 Å²	96	95.3 Å²	95.3	36%	0.362	46%	0.459	S	S	.	.	H	α-helix	trans	-65.8	-42	177.8	-167.5	-176.8	-57.9	-148.9	-6.6	112	S168 K169 R170 R180 N340	S168-R172 WeakPolarHBondContact O-CB 3.32Å; S168-R172 PolarHBondContact O-N 2.96Å; K169-R172 PolarHBondContact O-N 3.02Å; R170-R172 VanDerWaalsContact C-N 3.31Å; R170-R172 PolarHBondContact O-N 3.14Å; R172-R180 PolarHBondContact O-NH2 3.2Å; R172-N340 PolarHBondContact NH1-OD1 3.35Å; R172-N340 VanDerWaalsContact NH2-CA 3.32Å; R172-N340 VanDerWaalsContact NH2-CB 3.35Å; R172-N340 PolarHBondContact NH2-OD1 3.1Å
173	R	76.8	Confident	72.4	Confident	234 Å²	234	93.2 Å²	93.2	88%	0.883	45%	0.453	S	S	*	.	H	α-helix	trans	-67.5	-38.6	-179.1	-168	175.7	-178.1	172.7	0.3	112.3	K169 R170	K169-R173 PolarHBondContact O-N 3.22Å; R170-R173 PolarHBondContact O-N 3.36Å
174	T	74.5	Confident	70.8	Confident	110 Å²	110	90.4 Å²	90.4	68%	0.675	45%	0.453	S	S	*	.	H	α-helix	trans	-80.9	-29.8	-174.3	-52.3	0	0	0	0	113.8	R170	R170-T174 PolarHBondContact O-N 3.47Å; R170-T174 PolarHBondContact O-OG1 3.07Å; R170-T174 VanDerWaalsContact O-OG1 3.06Å
175	R	65.7	Low	69.5	Low	73 Å²	73	93.2 Å²	93.2	28%	0.275	47%	0.473	S	S	.	.	S	Bend	trans	-103.7	128.3	-177.8	-78.3	-170.7	169.2	177.3	-4.9	113.3	Y171 Q179 R180	Y171-R175 PolarHBondContact O-N 3.07Å; Y171-R175 PolarHBondContact OH-NH1 3.1Å; R175-Q179 HydrophobicContact CG-CG 4.42Å; R175-R180 HydrophobicContact CB-CG 3.99Å; R175-R180 VanDerWaalsContact O-CZ 3.29Å; R175-R180 PolarHBondContact O-NE 3.26Å; R175-R180 PolarHBondContact O-NH2 3.44Å
176	G	66.9	Low	68.5	Low	45 Å²	45	94.7 Å²	94.7	46%	0.464	48%	0.482	S	S	.	.			trans	-67.9	164.5	169.1	0	0	0	0	0	113.3	F178 Q179 R180	G176-F178 PolarHBondContact O-N 3.48Å; G176-Q179 PolarHBondContact O-N 3.15Å; G176-R180 WeakPolarHBondContact O-CG 3.15Å; G176-R180 PolarHBondContact O-N 2.94Å; G176-R180 VanDerWaalsContact O-N 3.13Å
177	I	67	Low	67.4	Low	136 Å²	136	92.1 Å²	92.1	70%	0.697	48%	0.475	S	S	*	.	H	α-helix	trans	-54.1	-47.5	-173.4	-63.4	170.4	0	0	0	112	Q179 R180 C181	I177-Q179 PolarHBondContact O-N 3.05Å; I177-R180 WeakPolarHBondContact O-CB 3.47Å; I177-R180 PolarHBondContact O-N 2.56Å; I177-C181 PolarHBondContact O-N 3.4Å
178	F	59.3	Low	66.8	Low	167 Å²	167	90.5 Å²	90.5	73%	0.732	46%	0.461	S	S	*	.	H	α-helix	trans	-62.9	-41.6	-178.9	-170.8	-104.5	0	0	0	112.8	G176 R180 C181 L182	G176-F178 PolarHBondContact O-N 3.48Å; F178-R180 VanDerWaalsContact C-N 3.26Å; F178-R180 PolarHBondContact O-N 2.92Å; F178-C181 PolarHBondContact O-N 3.27Å; F178-L182 HydrophobicContact CD1-CD1 4.1Å; F178-L182 HydrophobicContact CD2-CD1 4.42Å; F178-L182 HydrophobicContact CE1-CD1 3.54Å; F178-L182 HydrophobicContact CE2-CD1 3.9Å; F178-L182 HydrophobicContact CZ-CD1 3.42Å; F178-L182 VanDerWaalsContact CZ-CD1 3.42Å; F178-L182 PolarHBondContact O-N 3.31Å
179	Q	60.8	Low	66.7	Low	107 Å²	107	90.7 Å²	90.7	50%	0.5	46%	0.461	S	S	.	.	H	α-helix	trans	-73.8	-15.8	178.9	-155.4	178.2	17.7	0	0	113	R175 G176 I177 G183	R175-Q179 HydrophobicContact CG-CG 4.42Å; G176-Q179 PolarHBondContact O-N 3.15Å; I177-Q179 PolarHBondContact O-N 3.05Å; Q179-G183 VanDerWaalsContact O-CA 3.25Å; Q179-G183 WeakPolarHBondContact O-CA 3.31Å; Q179-G183 PolarHBondContact O-N 3.48Å
180	R	58.6	Low	66.8	Low	103 Å²	103	95.5 Å²	95.5	39%	0.389	48%	0.477	S	S	.	.	H	α-helix	trans	-79	-27.7	172	-69.1	177.2	-164	156.5	5	113.1	R172 R175 G176 I177 F178	R172-R180 PolarHBondContact O-NH2 3.2Å; R175-R180 HydrophobicContact CB-CG 3.99Å; R175-R180 VanDerWaalsContact O-CZ 3.29Å; R175-R180 PolarHBondContact O-NE 3.26Å; R175-R180 PolarHBondContact O-NH2 3.44Å; G176-R180 WeakPolarHBondContact O-CG 3.15Å; G176-R180 PolarHBondContact O-N 2.94Å; G176-R180 VanDerWaalsContact O-N 3.13Å; I177-R180 WeakPolarHBondContact O-CB 3.47Å; I177-R180 PolarHBondContact O-N 2.56Å; F178-R180 VanDerWaalsContact C-N 3.26Å; F178-R180 PolarHBondContact O-N 2.92Å
181	C	56.7	Low	67.2	Low	114 Å²	114	89.2 Å²	89.2	77%	0.77	46%	0.456	S	S	*	.	H	α-helix	trans	-80.9	-42.5	177.1	-74.8	0	0	0	0	112.1	I177 F178	I177-C181 PolarHBondContact O-N 3.4Å; F178-C181 PolarHBondContact O-N 3.27Å
182	L	57.2	Low	67.8	Low	131 Å²	131	87.1 Å²	87.1	69%	0.686	45%	0.448	S	S	*	.	H	α-helix	trans	-86.7	-29.2	179.6	-86.6	134	0	0	0	113.6	F178	F178-L182 HydrophobicContact CD1-CD1 4.1Å; F178-L182 HydrophobicContact CD2-CD1 4.42Å; F178-L182 HydrophobicContact CE1-CD1 3.54Å; F178-L182 HydrophobicContact CE2-CD1 3.9Å; F178-L182 HydrophobicContact CZ-CD1 3.42Å; F178-L182 VanDerWaalsContact CZ-CD1 3.42Å; F178-L182 PolarHBondContact O-N 3.31Å
183	G	49.8	Very low	68.5	Low	17 Å²	17	86.5 Å²	86.5	18%	0.175	45%	0.452	C	S	.	.	S	Bend	trans	-78.8	140.4	177.8	0	0	0	0	0	110.8	Q179	Q179-G183 VanDerWaalsContact O-CA 3.25Å; Q179-G183 WeakPolarHBondContact O-CA 3.31Å; Q179-G183 PolarHBondContact O-N 3.48Å
184	G	55.8	Low	69.2	Low	47 Å²	47	77 Å²	77	49%	0.485	42%	0.418	S	S	.	.	P	Polyproline II helix	trans	-47.2	167.7	-177.3	0	0	0	0	0	115.8	Y171	Y171-G184 PolarHBondContact OH-O 2.94Å; Y171-G184 VanDerWaalsContact OH-O 3.08Å
185	P	59.7	Low	70	Confident	86 Å²	86	72 Å²	72	56%	0.558	39%	0.387	S	S	*	.	P	Polyproline II helix	trans	-59.3	148.3	-165.2	30.1	-38.7	0	0	0	111.4	T189	P185-T189 WeakPolarHBondContact CB-OG1 3.25Å
186	P	63.7	Low	71.2	Confident	48 Å²	48	69.7 Å²	69.7	31%	0.312	38%	0.38	S	S	.	.	P	Polyproline II helix	trans	-56.6	147	-176.1	24	-32.6	0	0	0	110	Y171 T188 T189	Y171-P186 HydrophobicContact CD1-CB 3.95Å; Y171-P186 HydrophobicContact CE1-CB 3.74Å; P186-T188 PolarHBondContact O-N 2.88Å; P186-T189 HydrophobicContact CG-CG2 3.8Å; P186-T189 PolarHBondContact O-N 3.32Å; P186-T189 PolarHBondContact O-OG1 3.19Å
187	P	63.6	Low	72.5	Confident	54 Å²	54	70.6 Å²	70.6	35%	0.351	37%	0.373	S	S	.	.	G	3₁₀ helix	trans	-54.8	-23.9	-175.9	20.4	-31.9	0	0	0	113.1	Y171 T189 R190	Y171-P187 VanDerWaalsContact CD2-CD 3.4Å; Y171-P187 HydrophobicContact CD2-CG 4.07Å; Y171-P187 HydrophobicContact CG-CG 3.9Å; P187-T189 PolarHBondContact O-N 3.46Å; P187-R190 PolarHBondContact O-N 3.18Å
188	T	69.8	Low	73.7	Confident	8 Å²	8	64.3 Å²	64.3	5%	0.049	34%	0.341	C	S	.	.	G	3₁₀ helix	trans	-73.1	4.4	174.9	55.2	0	0	0	0	116.1	I164 S168 P186 W344 D345	I164-T188 HydrophobicContact CG2-CG2 4.08Å; S168-T188 WeakPolarHBondContact OG-CG2 3.44Å; P186-T188 PolarHBondContact O-N 2.88Å; T188-W344 PolarHBondContact O-N 2.91Å; T188-D345 VanDerWaalsContact O-CB 3.26Å; T188-D345 WeakPolarHBondContact O-CB 3.44Å; T188-D345 PolarHBondContact O-N 3.34Å
189	T	79.7	Confident	75.3	Confident	11 Å²	11	56.5 Å²	56.5	7%	0.067	31%	0.307	C	S	.	.	G	3₁₀ helix	trans	-118.8	-3.9	176.3	56.4	0	0	0	0	112.4	P185 P186 P187 T192 L193 W344 D345	P185-T189 WeakPolarHBondContact CB-OG1 3.25Å; P186-T189 HydrophobicContact CG-CG2 3.8Å; P186-T189 PolarHBondContact O-N 3.32Å; P186-T189 PolarHBondContact O-OG1 3.19Å; P187-T189 PolarHBondContact O-N 3.46Å; T189-T192 PolarHBondContact O-N 2.74Å; T189-L193 VanDerWaalsContact O-CB 3.22Å; T189-L193 WeakPolarHBondContact O-CB 3.39Å; T189-L193 PolarHBondContact O-N 3.02Å; T189-W344 HydrophobicContact CG2-CB 3.96Å; T189-W344 HydrophobicContact CG2-CD2 3.7Å; T189-W344 HydrophobicContact CG2-CE3 4.18Å; T189-W344 HydrophobicContact CG2-CG 3.6Å; T189-D345 VanDerWaalsContact C-OD1 3.23Å; T189-D345 WeakPolarHBondContact CA-OD1 3.31Å; T189-D345 PolarHBondContact N-OD2 3.12Å
190	R	85.1	Confident	76.9	Confident	197 Å²	197	56.5 Å²	56.5	74%	0.743	31%	0.309	S	S	*	.	H	α-helix	trans	-67.1	-43.9	-170.1	-177.3	-178.8	177.7	-179	0.9	111	P187 L194 D345	P187-R190 PolarHBondContact O-N 3.18Å; R190-L194 VanDerWaalsContact O-CB 3.28Å; R190-L194 WeakPolarHBondContact O-CB 3.48Å; R190-L194 PolarHBondContact O-N 3.23Å; R190-D345 PolarHBondContact N-OD2 3.06Å
191	I	88.1	Confident	78.6	Confident	44 Å²	44	55.9 Å²	55.9	23%	0.226	31%	0.31	C	S	.	.	H	α-helix	trans	-69.3	-43.5	-178.5	-61.4	174	0	0	0	109.8	W125 V132 L194 F195 D345 F348	W125-I191 HydrophobicContact CH2-CG2 4.36Å; V132-I191 HydrophobicContact CG2-CD1 4.03Å; V132-I191 HydrophobicContact CG2-CG2 3.74Å; I191-L194 WeakPolarHBondContact O-CB 3.43Å; I191-L194 PolarHBondContact O-N 2.9Å; I191-F195 WeakPolarHBondContact O-CB 3.45Å; I191-F195 PolarHBondContact O-N 3.32Å; I191-D345 HydrophobicContact CB-CB 4.29Å; I191-D345 PolarHBondContact N-OD1 3.35Å; I191-D345 PolarHBondContact N-OD2 3.43Å; I191-D345 VanDerWaalsContact N-OD2 3.15Å; I191-F348 HydrophobicContact CG2-CD1 3.88Å; I191-F348 HydrophobicContact CG2-CE1 3.72Å
192	T	89	Confident	80.4	Confident	2 Å²	2	50.7 Å²	50.7	1%	0.012	27%	0.274	C	S	.	.	H	α-helix	trans	-62.7	-46.4	179.6	-53.1	0	0	0	0	111	T189 L194 F195 L196 L306 W344 D345 F348	T189-T192 PolarHBondContact O-N 2.74Å; T192-L194 VanDerWaalsContact C-N 3.35Å; T192-L194 PolarHBondContact O-N 3.13Å; T192-F195 WeakPolarHBondContact O-CB 3.36Å; T192-F195 PolarHBondContact O-N 3.41Å; T192-L196 WeakPolarHBondContact O-CG 3.43Å; T192-L196 PolarHBondContact O-N 3.42Å; T192-L306 HydrophobicContact CG2-CB 4.33Å; T192-L306 HydrophobicContact CG2-CD1 3.77Å; T192-L306 HydrophobicContact CG2-CD2 4.18Å; T192-L306 HydrophobicContact CG2-CG 4.32Å; T192-W344 PolarHBondContact OG1-O 3.21Å; T192-D345 VanDerWaalsContact CB-OD1 3.3Å; T192-D345 WeakPolarHBondContact CB-OD1 3.39Å; T192-D345 PolarHBondContact N-OD1 3.2Å; T192-D345 WeakPolarHBondContact OG1-CA 3.45Å; T192-D345 PolarHBondContact OG1-N 3.49Å; T192-D345 PolarHBondContact OG1-OD1 3.01Å; T192-F348 HydrophobicContact CG2-CB 4.44Å
193	L	90.4	Very high	82.3	Confident	83 Å²	83	45.9 Å²	45.9	44%	0.435	25%	0.249	S	C	.	.	H	α-helix	trans	-62.2	-43.7	177.1	-178.8	65.3	0	0	0	111.2	T189 F195 L196 I197	T189-L193 VanDerWaalsContact O-CB 3.22Å; T189-L193 WeakPolarHBondContact O-CB 3.39Å; T189-L193 PolarHBondContact O-N 3.02Å; L193-F195 VanDerWaalsContact C-N 3.33Å; L193-F195 PolarHBondContact O-N 3.23Å; L193-L196 PolarHBondContact O-N 2.99Å; L193-I197 HydrophobicContact CD1-CD1 4.42Å; L193-I197 HydrophobicContact CG-CD1 3.99Å; L193-I197 VanDerWaalsContact O-CG1 3.31Å; L193-I197 WeakPolarHBondContact O-CG1 3.11Å; L193-I197 PolarHBondContact O-N 2.85Å
194	L	90.9	Very high	84.5	Confident	34 Å²	34	47.6 Å²	47.6	18%	0.178	26%	0.261	C	S	.	.	H	α-helix	trans	-59	-44.3	176.2	-177.3	67.7	0	0	0	111.8	W128 R190 I191 T192 I197 V198	W128-L194 HydrophobicContact CB-CD1 3.87Å; W128-L194 HydrophobicContact CB-CD2 3.7Å; W128-L194 HydrophobicContact CB-CG 4.31Å; W128-L194 HydrophobicContact CD2-CD1 4.02Å; W128-L194 HydrophobicContact CE3-CD1 3.42Å; W128-L194 VanDerWaalsContact CE3-CD1 3.42Å; W128-L194 HydrophobicContact CG-CD1 4.28Å; W128-L194 HydrophobicContact CZ3-CD1 4.18Å; R190-L194 VanDerWaalsContact O-CB 3.28Å; R190-L194 WeakPolarHBondContact O-CB 3.48Å; R190-L194 PolarHBondContact O-N 3.23Å; I191-L194 WeakPolarHBondContact O-CB 3.43Å; I191-L194 PolarHBondContact O-N 2.9Å; T192-L194 VanDerWaalsContact C-N 3.35Å; T192-L194 PolarHBondContact O-N 3.13Å; L194-I197 PolarHBondContact O-N 3.42Å; L194-V198 WeakPolarHBondContact O-CG2 3.49Å; L194-V198 PolarHBondContact O-N 2.93Å
195	F	91	Very high	86.4	Confident	4 Å²	4	45.7 Å²	45.7	2%	0.018	24%	0.24	C	C	.	.	H	α-helix	trans	-60.2	-45	175.9	175.5	-107.2	0	0	0	112	V22 W125 I191 T192 L193 I197 V198 R199 W302 F348	V22-F195 HydrophobicContact CB-CE2 3.86Å; V22-F195 HydrophobicContact CB-CZ 4.37Å; V22-F195 HydrophobicContact CG1-CE2 4.08Å; V22-F195 HydrophobicContact CG1-CZ 4.18Å; V22-F195 HydrophobicContact CG2-CD2 4.35Å; V22-F195 HydrophobicContact CG2-CE2 3.86Å; W125-F195 HydrophobicContact CE3-CD2 4.45Å; W125-F195 HydrophobicContact CH2-CB 4Å; W125-F195 AromaticContact CH2-CD2 3.98Å; W125-F195 HydrophobicContact CH2-CD2 3.98Å; W125-F195 HydrophobicContact CH2-CG 4.43Å; W125-F195 HydrophobicContact CZ2-CD2 4.38Å; W125-F195 HydrophobicContact CZ3-CB 3.67Å; W125-F195 HydrophobicContact CZ3-CD2 4.02Å; W125-F195 HydrophobicContact CZ3-CG 4.36Å; I191-F195 WeakPolarHBondContact O-CB 3.45Å; I191-F195 PolarHBondContact O-N 3.32Å; T192-F195 WeakPolarHBondContact O-CB 3.36Å; T192-F195 PolarHBondContact O-N 3.41Å; L193-F195 VanDerWaalsContact C-N 3.33Å; L193-F195 PolarHBondContact O-N 3.23Å; F195-I197 PolarHBondContact O-N 3.33Å; F195-V198 PolarHBondContact O-N 3.33Å; F195-R199 HydrophobicContact CZ-CG 4.5Å; F195-R199 WeakPolarHBondContact O-CG 3.45Å; F195-R199 PolarHBondContact O-N 2.91Å; F195-W302 HydrophobicContact CE1-CB 4.34Å; F195-W302 AromaticContact CE1-CD2 3.78Å; F195-W302 HydrophobicContact CE1-CD2 3.78Å; F195-W302 HydrophobicContact CE1-CE3 4Å; F195-W302 AromaticContact CE1-CG 3.97Å; F195-W302 HydrophobicContact CE1-CG 3.97Å; F195-W302 HydrophobicContact CZ-CD2 4.13Å; F195-W302 HydrophobicContact CZ-CG 4.4Å; F195-W302 HydrophobicContact CZ-CZ2 4.33Å; F195-F348 HydrophobicContact CB-CE2 4.04Å; F195-F348 HydrophobicContact CB-CZ 3.97Å; F195-F348 HydrophobicContact CD1-CD2 4.02Å; F195-F348 AromaticContact CD1-CE2 3.41Å; F195-F348 HydrophobicContact CD1-CE2 3.41Å; F195-F348 VanDerWaalsContact CD1-CE2 3.41Å; F195-F348 HydrophobicContact CD1-CZ 4.15Å; F195-F348 AromaticContact CD2-CE2 3.76Å; F195-F348 HydrophobicContact CD2-CE2 3.76Å; F195-F348 AromaticContact CD2-CZ 3.74Å; F195-F348 HydrophobicContact CD2-CZ 3.74Å; F195-F348 HydrophobicContact CE1-CD2 4.29Å; F195-F348 AromaticContact CE1-CE2 3.62Å; F195-F348 HydrophobicContact CE1-CE2 3.62Å; F195-F348 AromaticContact CE2-CE2 3.97Å; F195-F348 HydrophobicContact CE2-CE2 3.97Å; F195-F348 HydrophobicContact CE2-CZ 4.19Å; F195-F348 HydrophobicContact CG-CD2 4.35Å; F195-F348 AromaticContact CG-CE2 3.46Å; F195-F348 HydrophobicContact CG-CE2 3.46Å; F195-F348 VanDerWaalsContact CG-CE2 3.46Å; F195-F348 AromaticContact CG-CZ 3.69Å; F195-F348 HydrophobicContact CG-CZ 3.69Å; F195-F348 AromaticContact CZ-CE2 3.86Å; F195-F348 HydrophobicContact CZ-CE2 3.86Å
196	L	92.2	Very high	88.1	Confident	26 Å²	26	41.7 Å²	41.7	14%	0.136	21%	0.214	C	C	.	.	H	α-helix	trans	-63.6	-39.9	176.4	-67.9	176	0	0	0	112.1	T192 L193 R199 I200 I303 L306	T192-L196 WeakPolarHBondContact O-CG 3.43Å; T192-L196 PolarHBondContact O-N 3.42Å; L193-L196 PolarHBondContact O-N 2.99Å; L196-R199 WeakPolarHBondContact O-CB 3.47Å; L196-R199 PolarHBondContact O-N 3.05Å; L196-I200 WeakPolarHBondContact O-CG1 3.43Å; L196-I200 PolarHBondContact O-N 3.09Å; L196-I303 HydrophobicContact CD2-CG1 3.86Å; L196-L306 HydrophobicContact CD2-CD1 4.39Å
197	I	93.1	Very high	89.6	Confident	63 Å²	63	43.9 Å²	43.9	32%	0.323	22%	0.222	S	C	.	.	H	α-helix	trans	-61.6	-45.8	175	-71.5	166.9	0	0	0	110.9	L193 L194 F195 R199 I200 F201	L193-I197 HydrophobicContact CD1-CD1 4.42Å; L193-I197 HydrophobicContact CG-CD1 3.99Å; L193-I197 VanDerWaalsContact O-CG1 3.31Å; L193-I197 WeakPolarHBondContact O-CG1 3.11Å; L193-I197 PolarHBondContact O-N 2.85Å; L194-I197 PolarHBondContact O-N 3.42Å; F195-I197 PolarHBondContact O-N 3.33Å; I197-R199 VanDerWaalsContact C-N 3.27Å; I197-R199 PolarHBondContact O-N 2.95Å; I197-I200 WeakPolarHBondContact O-CB 3.45Å; I197-I200 PolarHBondContact O-N 3.33Å; I197-I200 VanDerWaalsContact O-N 3.14Å; I197-F201 HydrophobicContact CG2-CD2 3.82Å; I197-F201 HydrophobicContact CG2-CE2 3.47Å; I197-F201 VanDerWaalsContact CG2-CE2 3.47Å; I197-F201 VanDerWaalsContact O-CD2 3.25Å; I197-F201 WeakPolarHBondContact O-CD2 3.37Å; I197-F201 PolarHBondContact O-N 3.05Å
198	V	93	Very high	91.1	Very high	4 Å²	4	42.3 Å²	42.3	2%	0.024	22%	0.216	C	C	.	.	H	α-helix	trans	-60.1	-38.7	176.5	168.8	0	0	0	0	111.6	P121 W125 L194 F195 I200 F201 F202	P121-V198 HydrophobicContact CB-CG1 4.29Å; P121-V198 WeakPolarHBondContact O-CG1 3.37Å; W125-V198 HydrophobicContact CB-CG1 4.13Å; W125-V198 HydrophobicContact CB-CG2 4.22Å; W125-V198 HydrophobicContact CE3-CG2 4.34Å; L194-V198 WeakPolarHBondContact O-CG2 3.49Å; L194-V198 PolarHBondContact O-N 2.93Å; F195-V198 PolarHBondContact O-N 3.33Å; V198-I200 VanDerWaalsContact C-N 3.34Å; V198-I200 PolarHBondContact O-N 3.07Å; V198-F201 CarbonylContact O-C 3.45Å; V198-F201 WeakPolarHBondContact O-CA 3.41Å; V198-F201 WeakPolarHBondContact O-CB 3.49Å; V198-F201 PolarHBondContact O-N 3.46Å; V198-F201 VanDerWaalsContact O-N 3.1Å; V198-F202 HydrophobicContact CG1-CD2 3.89Å; V198-F202 HydrophobicContact CG1-CE2 3.74Å; V198-F202 WeakPolarHBondContact O-CD2 3.28Å; V198-F202 PolarHBondContact O-N 3.49Å
199	R	92.8	Very high	92.3	Very high	3 Å²	3	42 Å²	42	1%	0.011	21%	0.214	C	C	.	.	H	α-helix	trans	-63.4	-39.4	175.4	-76.7	178.5	157.8	-87.7	-10	112.9	D23 D26 F195 L196 I197 F201 F202 I203 N298 T299 W302	D23-R199 IonicContact OD2-CZ 3.41Å; D23-R199 IonicContact OD2-NH2 3.82Å; D23-R199 PolarHBondContact OD2-NH2 2.97Å; D26-R199 IonicContact OD1-NH2 2.72Å; F195-R199 HydrophobicContact CZ-CG 4.5Å; F195-R199 WeakPolarHBondContact O-CG 3.45Å; F195-R199 PolarHBondContact O-N 2.91Å; L196-R199 WeakPolarHBondContact O-CB 3.47Å; L196-R199 PolarHBondContact O-N 3.05Å; I197-R199 VanDerWaalsContact C-N 3.27Å; I197-R199 PolarHBondContact O-N 2.95Å; R199-F201 VanDerWaalsContact C-N 3.26Å; R199-F201 PolarHBondContact O-N 2.93Å; R199-F202 WeakPolarHBondContact O-CB 3.19Å; R199-F202 PolarHBondContact O-N 3.24Å; R199-F202 VanDerWaalsContact O-N 3.15Å; R199-I203 WeakPolarHBondContact O-CG1 3.3Å; R199-I203 PolarHBondContact O-N 2.97Å; R199-N298 VanDerWaalsContact NH1-C 3.33Å; R199-N298 PolarHBondContact NH1-ND2 3.44Å; R199-N298 PolarHBondContact NH2-ND2 3.3Å; R199-T299 HydrophobicContact CB-CG2 4.04Å; R199-T299 VanDerWaalsContact NH1-N 3.12Å; R199-T299 PolarHBondContact NH1-OG1 2.71Å; R199-W302 VanDerWaalsContact NH2-NE1 3.13Å
200	I	94.1	Very high	93.1	Very high	107 Å²	107	42.4 Å²	42.4	55%	0.549	22%	0.215	S	C	.	.	H	α-helix	trans	-61	-40.5	172.4	-65.2	166.2	0	0	0	109.8	L196 I197 V198 F202 I203 A204	L196-I200 WeakPolarHBondContact O-CG1 3.43Å; L196-I200 PolarHBondContact O-N 3.09Å; I197-I200 WeakPolarHBondContact O-CB 3.45Å; I197-I200 PolarHBondContact O-N 3.33Å; I197-I200 VanDerWaalsContact O-N 3.14Å; V198-I200 VanDerWaalsContact C-N 3.34Å; V198-I200 PolarHBondContact O-N 3.07Å; I200-F202 PolarHBondContact O-N 3.42Å; I200-I203 PolarHBondContact O-N 3.24Å; I200-A204 VanDerWaalsContact O-CB 3.27Å; I200-A204 WeakPolarHBondContact O-CB 3.38Å; I200-A204 PolarHBondContact O-N 3.43Å
201	F	95.3	Very high	93.5	Very high	91 Å²	91	39.9 Å²	39.9	40%	0.399	21%	0.206	S	C	.	.	H	α-helix	trans	-63.4	-35.7	173.4	-75.7	-64.3	0	0	0	113.6	P121 L124 W128 I197 V198 R199 N205	P121-F201 HydrophobicContact CB-CB 4.09Å; P121-F201 HydrophobicContact CG-CB 4.16Å; L124-F201 HydrophobicContact CD1-CD2 4.16Å; L124-F201 HydrophobicContact CD1-CE2 4.37Å; L124-F201 HydrophobicContact CD1-CG 4.37Å; W128-F201 HydrophobicContact CH2-CE2 4.29Å; W128-F201 HydrophobicContact CZ3-CE2 4.24Å; I197-F201 HydrophobicContact CG2-CD2 3.82Å; I197-F201 HydrophobicContact CG2-CE2 3.47Å; I197-F201 VanDerWaalsContact CG2-CE2 3.47Å; I197-F201 VanDerWaalsContact O-CD2 3.25Å; I197-F201 WeakPolarHBondContact O-CD2 3.37Å; I197-F201 PolarHBondContact O-N 3.05Å; V198-F201 CarbonylContact O-C 3.45Å; V198-F201 WeakPolarHBondContact O-CA 3.41Å; V198-F201 WeakPolarHBondContact O-CB 3.49Å; V198-F201 PolarHBondContact O-N 3.46Å; V198-F201 VanDerWaalsContact O-N 3.1Å; R199-F201 VanDerWaalsContact C-N 3.26Å; R199-F201 PolarHBondContact O-N 2.93Å; F201-N205 WeakPolarHBondContact O-CB 3.3Å; F201-N205 PolarHBondContact O-N 3.31Å
202	F	94.6	Very high	93.8	Very high	5 Å²	5	40.2 Å²	40.2	2%	0.022	21%	0.21	C	C	.	.	H	α-helix	trans	-63.5	-44.8	172	-85.6	-70.9	0	0	0	112.2	D26 N29 Y30 P121 H122 V198 R199 I200 N205 N206	D26-F202 HydrophobicContact CB-CE2 4.32Å; D26-F202 HydrophobicContact CB-CZ 4.22Å; N29-F202 HydrophobicContact CB-CD1 3.63Å; N29-F202 HydrophobicContact CB-CE1 3.72Å; Y30-F202 HydrophobicContact CD1-CE1 4.41Å; Y30-F202 HydrophobicContact CD1-CZ 4.24Å; P121-F202 HydrophobicContact CB-CD1 3.82Å; P121-F202 HydrophobicContact CB-CD2 3.63Å; P121-F202 HydrophobicContact CB-CE1 3.83Å; P121-F202 HydrophobicContact CB-CE2 3.65Å; P121-F202 HydrophobicContact CB-CG 3.73Å; P121-F202 HydrophobicContact CB-CZ 3.76Å; P121-F202 HydrophobicContact CG-CD1 3.97Å; P121-F202 HydrophobicContact CG-CE1 4.21Å; P121-F202 HydrophobicContact CG-CG 4.15Å; H122-F202 HydrophobicContact CB-CZ 4.18Å; V198-F202 HydrophobicContact CG1-CD2 3.89Å; V198-F202 HydrophobicContact CG1-CE2 3.74Å; V198-F202 WeakPolarHBondContact O-CD2 3.28Å; V198-F202 PolarHBondContact O-N 3.49Å; R199-F202 WeakPolarHBondContact O-CB 3.19Å; R199-F202 PolarHBondContact O-N 3.24Å; R199-F202 VanDerWaalsContact O-N 3.15Å; I200-F202 PolarHBondContact O-N 3.42Å; F202-N205 PolarHBondContact O-N 3.09Å; F202-N206 PolarHBondContact O-N 3.29Å; F202-N206 PolarHBondContact O-ND2 3.2Å
203	I	95.7	Very high	94	Very high	30 Å²	30	40.1 Å²	40.1	15%	0.154	21%	0.21	C	C	.	.	H	α-helix	trans	-63.5	-47.7	176.9	-64.5	166.3	0	0	0	110.2	R199 I200 N205 N206 I207 I296 T299	R199-I203 WeakPolarHBondContact O-CG1 3.3Å; R199-I203 PolarHBondContact O-N 2.97Å; I200-I203 PolarHBondContact O-N 3.24Å; I203-N205 VanDerWaalsContact C-N 3.29Å; I203-N205 PolarHBondContact O-N 3.49Å; I203-N206 PolarHBondContact O-N 2.92Å; I203-I207 HydrophobicContact CG2-CD1 3.84Å; I203-I207 WeakPolarHBondContact O-CG1 3.42Å; I203-I207 PolarHBondContact O-N 2.82Å; I203-I296 HydrophobicContact CD1-CG1 4.01Å; I203-I296 HydrophobicContact CG1-CG1 4.06Å; I203-I296 HydrophobicContact CG2-CD1 4.3Å; I203-I296 HydrophobicContact CG2-CG1 3.94Å; I203-T299 HydrophobicContact CD1-CG2 4.15Å
204	A	96.2	Very high	94	Very high	52 Å²	52	38 Å²	38	43%	0.43	20%	0.197	S	C	.	.	H	α-helix	trans	-62	-37	177.9	0	0	0	0	0	111.8	I200 G208	I200-A204 VanDerWaalsContact O-CB 3.27Å; I200-A204 WeakPolarHBondContact O-CB 3.38Å; I200-A204 PolarHBondContact O-N 3.43Å; A204-G208 WeakPolarHBondContact O-CA 3.28Å; A204-G208 PolarHBondContact O-N 2.61Å
205	N	96.1	Very high	94.1	Very high	8 Å²	8	43.1 Å²	43.1	4%	0.043	22%	0.22	C	C	.	.	H	α-helix	trans	-61.8	-50.9	173.1	176.5	65.7	0	0	0	110.8	M117 P121 F201 F202 I203 I207 G208 Q209	M117-N205 WeakPolarHBondContact CG-OD1 3.47Å; M117-N205 PolarHBondContact O-OD1 3.02Å; P121-N205 HydrophobicContact CG-CB 4.25Å; F201-N205 WeakPolarHBondContact O-CB 3.3Å; F201-N205 PolarHBondContact O-N 3.31Å; F202-N205 PolarHBondContact O-N 3.09Å; I203-N205 VanDerWaalsContact C-N 3.29Å; I203-N205 PolarHBondContact O-N 3.49Å; N205-I207 PolarHBondContact O-N 3.21Å; N205-G208 CarbonylContact O-C 3.58Å; N205-G208 WeakPolarHBondContact O-CA 3.22Å; N205-G208 PolarHBondContact O-N 2.84Å; N205-G208 VanDerWaalsContact O-N 3.12Å; N205-Q209 VanDerWaalsContact O-CG 3.31Å; N205-Q209 WeakPolarHBondContact O-CG 3.43Å; N205-Q209 PolarHBondContact O-N 3.36Å; N205-Q209 PolarHBondContact OD1-NE2 2.88Å
206	N	96.1	Very high	94	Very high	1 Å²	1	44.9 Å²	44.9	1%	0.005	23%	0.228	C	C	.	.	H	α-helix	trans	-58.7	-45.2	179.7	-72.7	-40.1	0	0	0	112.9	N29 F202 I203 G208 Q209 I210 A292 T295	N29-N206 PolarHBondContact OD1-ND2 2.88Å; N29-N206 PolarHBondContact OD1-OD1 3.33Å; N29-N206 VanDerWaalsContact OD1-OD1 3.12Å; F202-N206 PolarHBondContact O-N 3.29Å; F202-N206 PolarHBondContact O-ND2 3.2Å; I203-N206 PolarHBondContact O-N 2.92Å; N206-G208 VanDerWaalsContact C-N 3.33Å; N206-Q209 PolarHBondContact O-N 3.08Å; N206-I210 PolarHBondContact O-N 3.2Å; N206-A292 HydrophobicContact CB-CB 4.04Å; N206-T295 PolarHBondContact ND2-OG1 3.41Å
207	I	95.1	Very high	93.8	Very high	95 Å²	95	43.9 Å²	43.9	49%	0.487	22%	0.223	S	C	.	.	H	α-helix	trans	-65.4	-41.5	176.1	-63.6	170.7	0	0	0	110.3	I203 N205 Q209 I210 Y211	I203-I207 HydrophobicContact CG2-CD1 3.84Å; I203-I207 WeakPolarHBondContact O-CG1 3.42Å; I203-I207 PolarHBondContact O-N 2.82Å; N205-I207 PolarHBondContact O-N 3.21Å; I207-Q209 VanDerWaalsContact C-N 3.33Å; I207-Q209 PolarHBondContact O-N 3.36Å; I207-I210 PolarHBondContact O-N 3.21Å; I207-Y211 PolarHBondContact O-N 3.17Å; I207-Y211 VanDerWaalsContact O-N 3.1Å
208	G	95.2	Very high	93.3	Very high	21 Å²	21	43.2 Å²	43.2	22%	0.216	23%	0.231	C	C	.	.	H	α-helix	trans	-59.3	-40.4	175.9	0	0	0	0	0	112.7	A204 N205 N206 I210 Y211 V212	A204-G208 WeakPolarHBondContact O-CA 3.28Å; A204-G208 PolarHBondContact O-N 2.61Å; N205-G208 CarbonylContact O-C 3.58Å; N205-G208 WeakPolarHBondContact O-CA 3.22Å; N205-G208 PolarHBondContact O-N 2.84Å; N205-G208 VanDerWaalsContact O-N 3.12Å; N206-G208 VanDerWaalsContact C-N 3.33Å; G208-I210 VanDerWaalsContact C-N 3.35Å; G208-I210 PolarHBondContact O-N 3.11Å; G208-Y211 WeakPolarHBondContact O-CB 3.35Å; G208-Y211 PolarHBondContact O-N 2.92Å; G208-Y211 VanDerWaalsContact O-N 3.14Å; G208-V212 WeakPolarHBondContact O-CG2 3.45Å; G208-V212 PolarHBondContact O-N 3.11Å
209	Q	95.4	Very high	92.9	Very high	1 Å²	1	43.9 Å²	43.9	1%	0.005	24%	0.235	C	C	.	.	H	α-helix	trans	-61.6	-42.6	176.6	-65.3	-51.6	-28.3	0	0	111.9	Q114 M117 N205 N206 I207 Y211 V212 M213 Y288	Q114-Q209 VanDerWaalsContact CB-OE1 3.27Å; M117-Q209 PolarHBondContact SD-NE2 3.42Å; N205-Q209 VanDerWaalsContact O-CG 3.31Å; N205-Q209 WeakPolarHBondContact O-CG 3.43Å; N205-Q209 PolarHBondContact O-N 3.36Å; N205-Q209 PolarHBondContact OD1-NE2 2.88Å; N206-Q209 PolarHBondContact O-N 3.08Å; I207-Q209 VanDerWaalsContact C-N 3.33Å; I207-Q209 PolarHBondContact O-N 3.36Å; Q209-Y211 VanDerWaalsContact C-N 3.28Å; Q209-Y211 PolarHBondContact O-N 3.23Å; Q209-V212 PolarHBondContact O-N 3.3Å; Q209-M213 VanDerWaalsContact O-CG 3.31Å; Q209-M213 WeakPolarHBondContact O-CG 3.41Å; Q209-M213 PolarHBondContact O-N 3.38Å; Q209-Y288 HydrophobicContact CB-CD1 3.92Å; Q209-Y288 HydrophobicContact CB-CD2 4.07Å; Q209-Y288 HydrophobicContact CB-CE1 3.67Å; Q209-Y288 HydrophobicContact CB-CE2 3.82Å; Q209-Y288 HydrophobicContact CB-CG 4.12Å; Q209-Y288 HydrophobicContact CG-CD1 4.19Å; Q209-Y288 HydrophobicContact CG-CE1 3.57Å; Q209-Y288 HydrophobicContact CG-CE2 4.42Å
210	I	94.9	Very high	92.4	Very high	20 Å²	20	50.4 Å²	50.4	10%	0.103	27%	0.27	C	S	.	.	H	α-helix	trans	-61	-41.5	175.3	-62.4	168.8	0	0	0	110.3	N206 I207 G208 M213 K214 I289	N206-I210 PolarHBondContact O-N 3.2Å; I207-I210 PolarHBondContact O-N 3.21Å; G208-I210 VanDerWaalsContact C-N 3.35Å; G208-I210 PolarHBondContact O-N 3.11Å; I210-M213 PolarHBondContact O-N 3.28Å; I210-K214 WeakPolarHBondContact O-CB 3.5Å; I210-K214 PolarHBondContact O-N 3.46Å; I210-I289 HydrophobicContact CD1-CD1 3.6Å; I210-I289 HydrophobicContact CD1-CG1 4.17Å
211	Y	94.1	Very high	92	Very high	143 Å²	143	49.8 Å²	49.8	56%	0.561	27%	0.268	S	S	*	.	H	α-helix	trans	-66.9	-41.1	176.9	-172.2	-96.1	0	0	0	112.8	I207 G208 Q209 M213 K214 H215	I207-Y211 PolarHBondContact O-N 3.17Å; I207-Y211 VanDerWaalsContact O-N 3.1Å; G208-Y211 WeakPolarHBondContact O-CB 3.35Å; G208-Y211 PolarHBondContact O-N 2.92Å; G208-Y211 VanDerWaalsContact O-N 3.14Å; Q209-Y211 VanDerWaalsContact C-N 3.28Å; Q209-Y211 PolarHBondContact O-N 3.23Å; Y211-M213 VanDerWaalsContact C-N 3.33Å; Y211-M213 PolarHBondContact O-N 2.6Å; Y211-K214 PolarHBondContact O-N 2.76Å; Y211-H215 WeakPolarHBondContact O-CB 3.49Å; Y211-H215 PolarHBondContact O-N 3.13Å
212	V	94.2	Very high	91.6	Very high	51 Å²	51	49 Å²	49	31%	0.309	27%	0.271	S	S	.	.	H	α-helix	trans	-60.2	-44.8	174.6	170.8	0	0	0	0	110.3	I110 Q114 G208 Q209 H215 F216	I110-V212 HydrophobicContact CG2-CG1 4.26Å; Q114-V212 HydrophobicContact CG-CG1 4.39Å; G208-V212 WeakPolarHBondContact O-CG2 3.45Å; G208-V212 PolarHBondContact O-N 3.11Å; Q209-V212 PolarHBondContact O-N 3.3Å; V212-H215 PolarHBondContact O-N 3.46Å; V212-F216 VanDerWaalsContact O-CB 3.28Å; V212-F216 WeakPolarHBondContact O-CB 3.36Å; V212-F216 PolarHBondContact O-N 2.98Å
213	M	93.3	Very high	91.4	Very high	0 Å²	0	53.8 Å²	53.8	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-62.4	-46.2	176.9	-69.1	172.4	65.2	0	0	112	Q209 I210 Y211 H215 F216 I217 F224 Y281 L284 W285 Y288	Q209-M213 VanDerWaalsContact O-CG 3.31Å; Q209-M213 WeakPolarHBondContact O-CG 3.41Å; Q209-M213 PolarHBondContact O-N 3.38Å; I210-M213 PolarHBondContact O-N 3.28Å; Y211-M213 VanDerWaalsContact C-N 3.33Å; Y211-M213 PolarHBondContact O-N 2.6Å; M213-H215 PolarHBondContact O-N 3.2Å; M213-F216 PolarHBondContact O-N 2.83Å; M213-I217 WeakPolarHBondContact O-CG1 3.48Å; M213-I217 PolarHBondContact O-N 3.08Å; M213-I217 VanDerWaalsContact O-N 3.1Å; M213-F224 HydrophobicContact CB-CE1 4.17Å; M213-F224 HydrophobicContact CB-CZ 3.87Å; M213-F224 HydrophobicContact CE-CZ 3.89Å; M213-Y281 HydrophobicContact CB-CD1 4.3Å; M213-Y281 HydrophobicContact CB-CE1 4.13Å; M213-Y281 HydrophobicContact CE-CD1 3.59Å; M213-Y281 HydrophobicContact CE-CE1 4.24Å; M213-Y281 HydrophobicContact CE-CG 4.09Å; M213-Y281 VanDerWaalsContact CE-O 3.28Å; M213-Y281 WeakPolarHBondContact CE-O 3.47Å; M213-Y281 HydrophobicContact CG-CD1 4.33Å; M213-Y281 HydrophobicContact CG-CE1 4.07Å; M213-L284 HydrophobicContact CE-CB 3.83Å; M213-L284 HydrophobicContact SD-CB 4.25Å; M213-W285 HydrophobicContact CE-CB 4.24Å; M213-Y288 HydrophobicContact SD-CD2 3.67Å; M213-Y288 HydrophobicContact SD-CE2 3.66Å
214	K	91.7	Very high	91	Very high	39 Å²	39	52.5 Å²	52.5	17%	0.17	29%	0.289	C	S	.	.	H	α-helix	trans	-55.6	-51.9	175.2	170.4	-175.1	159.6	171	0	111.1	I210 Y211 F216 I217 G218 T219 N220 T222 F224	I210-K214 WeakPolarHBondContact O-CB 3.5Å; I210-K214 PolarHBondContact O-N 3.46Å; Y211-K214 PolarHBondContact O-N 2.76Å; K214-F216 VanDerWaalsContact C-N 3.32Å; K214-F216 PolarHBondContact O-N 3.36Å; K214-I217 PolarHBondContact O-N 3.18Å; K214-G218 PolarHBondContact O-N 2.9Å; K214-G218 VanDerWaalsContact O-N 3.17Å; K214-T219 VanDerWaalsContact CE-O 3.3Å; K214-T219 WeakPolarHBondContact CE-O 3.31Å; K214-T219 HydrophobicContact CG-CG2 4.26Å; K214-T219 WeakPolarHBondContact CG-O 3.24Å; K214-T219 PolarHBondContact O-N 3.44Å; K214-N220 WeakPolarHBondContact CE-O 3.32Å; K214-N220 PolarHBondContact NZ-O 3.18Å; K214-T222 HydrophobicContact CD-CG2 3.77Å; K214-F224 HydrophobicContact CB-CD1 4.41Å; K214-F224 HydrophobicContact CB-CE1 4.37Å
215	H	91.4	Very high	90.6	Very high	142 Å²	142	50 Å²	50	66%	0.657	27%	0.269	S	S	*	.	H	α-helix	trans	-62.8	-39.9	-177.9	-176.3	66.8	0	0	0	111.8	Y211 V212 M213 G218	Y211-H215 WeakPolarHBondContact O-CB 3.49Å; Y211-H215 PolarHBondContact O-N 3.13Å; V212-H215 PolarHBondContact O-N 3.46Å; M213-H215 PolarHBondContact O-N 3.2Å; H215-G218 PolarHBondContact O-N 3.31Å; H215-G218 VanDerWaalsContact O-N 3.17Å
216	F	90.2	Very high	90.3	Very high	41 Å²	41	52.6 Å²	52.6	18%	0.18	28%	0.282	C	S	.	.	H	α-helix	trans	-68.8	-38	-178.5	-173.5	-111.7	0	0	0	113.8	Y103 W106 V107 I110 V212 M213 K214 G218 Y281	Y103-F216 HydrophobicContact CD2-CE1 4.43Å; Y103-F216 HydrophobicContact CG-CE1 4.43Å; Y103-F216 WeakPolarHBondContact O-CE1 3.38Å; Y103-F216 WeakPolarHBondContact O-CZ 3.27Å; W106-F216 HydrophobicContact CB-CE2 4Å; W106-F216 HydrophobicContact CB-CZ 3.93Å; V107-F216 HydrophobicContact CB-CE1 4.3Å; V107-F216 HydrophobicContact CG2-CE1 4.4Å; I110-F216 HydrophobicContact CB-CE2 4.44Å; I110-F216 HydrophobicContact CB-CZ 4.42Å; I110-F216 HydrophobicContact CD1-CD2 4.5Å; I110-F216 HydrophobicContact CD1-CE2 4.35Å; I110-F216 HydrophobicContact CG1-CD2 3.86Å; I110-F216 HydrophobicContact CG1-CE2 3.49Å; I110-F216 VanDerWaalsContact CG1-CE2 3.49Å; I110-F216 HydrophobicContact CG1-CZ 3.83Å; V212-F216 VanDerWaalsContact O-CB 3.28Å; V212-F216 WeakPolarHBondContact O-CB 3.36Å; V212-F216 PolarHBondContact O-N 2.98Å; M213-F216 PolarHBondContact O-N 2.83Å; K214-F216 VanDerWaalsContact C-N 3.32Å; K214-F216 PolarHBondContact O-N 3.36Å; F216-G218 PolarHBondContact O-N 2.89Å; F216-Y281 HydrophobicContact CD1-CE1 4.3Å; F216-Y281 AromaticContact CD1-CZ 3.98Å; F216-Y281 WeakPolarHBondContact CD1-OH 3.43Å; F216-Y281 WeakPolarHBondContact CE1-OH 3.45Å
217	I	87.3	Confident	90	Very high	5 Å²	5	56.3 Å²	56.3	3%	0.026	30%	0.299	C	S	.	.	H	α-helix	trans	-70.3	-25.4	173.2	-65.6	162.7	0	0	0	110.9	R99 M213 K214 T219 F224 L243 F244 Y281	R99-I217 PolarHBondContact NH2-O 3.07Å; M213-I217 WeakPolarHBondContact O-CG1 3.48Å; M213-I217 PolarHBondContact O-N 3.08Å; M213-I217 VanDerWaalsContact O-N 3.1Å; K214-I217 PolarHBondContact O-N 3.18Å; I217-T219 HydrophobicContact CB-CG2 4.34Å; I217-T219 HydrophobicContact CG2-CG2 4.18Å; I217-F224 HydrophobicContact CD1-CD2 3.69Å; I217-F224 HydrophobicContact CD1-CE1 4.48Å; I217-F224 HydrophobicContact CD1-CE2 3.34Å; I217-F224 HydrophobicContact CD1-CG 4.41Å; I217-F224 HydrophobicContact CD1-CZ 3.79Å; I217-L243 HydrophobicContact CG2-CD2 3.61Å; I217-F244 HydrophobicContact CD1-CE2 4.23Å; I217-F244 HydrophobicContact CD1-CZ 3.62Å; I217-F244 HydrophobicContact CG1-CE1 4.39Å; I217-F244 HydrophobicContact CG1-CZ 3.86Å; I217-F244 HydrophobicContact CG2-CZ 4.5Å; I217-Y281 HydrophobicContact CD1-CD1 3.59Å; I217-Y281 HydrophobicContact CD1-CE1 4.07Å; I217-Y281 HydrophobicContact CD1-CG 4.47Å; I217-Y281 HydrophobicContact CG1-CD1 4.07Å; I217-Y281 HydrophobicContact CG1-CE1 4.09Å
218	G	83.4	Confident	89.6	Confident	48 Å²	48	52.1 Å²	52.1	50%	0.495	28%	0.278	S	S	.	.	T	Hydrogen-bonded Turn	trans	75.6	31	-175.2	0	0	0	0	0	112.7	R99 K214 H215 F216	R99-G218 PolarHBondContact NH2-O 2.69Å; K214-G218 PolarHBondContact O-N 2.9Å; K214-G218 VanDerWaalsContact O-N 3.17Å; H215-G218 PolarHBondContact O-N 3.31Å; H215-G218 VanDerWaalsContact O-N 3.17Å; F216-G218 PolarHBondContact O-N 2.89Å
219	T	82.9	Confident	89.3	Confident	19 Å²	19	55 Å²	55	12%	0.117	29%	0.285	C	S	.	.			trans	-97.5	148.3	171.3	-177.3	0	0	0	0	110.8	K214 I217 D221 F224	K214-T219 VanDerWaalsContact CE-O 3.3Å; K214-T219 WeakPolarHBondContact CE-O 3.31Å; K214-T219 HydrophobicContact CG-CG2 4.26Å; K214-T219 WeakPolarHBondContact CG-O 3.24Å; K214-T219 PolarHBondContact O-N 3.44Å; I217-T219 HydrophobicContact CB-CG2 4.34Å; I217-T219 HydrophobicContact CG2-CG2 4.18Å; T219-D221 VanDerWaalsContact C-N 3.34Å; T219-D221 PolarHBondContact OG1-N 3.15Å; T219-F224 HydrophobicContact CG2-CB 3.7Å; T219-F224 HydrophobicContact CG2-CD1 4.22Å; T219-F224 HydrophobicContact CG2-CG 4.01Å
220	N	83.8	Confident	89	Confident	140 Å²	140	59.4 Å²	59.4	75%	0.749	31%	0.306	S	S	*	.	S	Bend	trans	-83.2	-13.8	176.1	-72.8	-27.8	0	0	0	112.6	K214	K214-N220 WeakPolarHBondContact CE-O 3.32Å; K214-N220 PolarHBondContact NZ-O 3.18Å
221	D	86.2	Confident	88.5	Confident	93 Å²	93	60 Å²	60	50%	0.497	31%	0.308	S	S	.	.			trans	-92.1	127.4	-174.6	-61.8	-31.6	0	0	0	111.8	T219 L223	T219-D221 VanDerWaalsContact C-N 3.34Å; T219-D221 PolarHBondContact OG1-N 3.15Å; D221-L223 VanDerWaalsContact C-N 3.28Å
222	T	86.2	Confident	88.1	Confident	76 Å²	76	56.1 Å²	56.1	47%	0.466	30%	0.296	S	S	.	.	T	Hydrogen-bonded Turn	trans	-73.9	-24.6	173.9	52.6	0	0	0	0	112.2	K214 F224 W285	K214-T222 HydrophobicContact CD-CG2 3.77Å; T222-F224 VanDerWaalsContact C-N 3.27Å; T222-F224 PolarHBondContact O-N 3.22Å; T222-W285 PolarHBondContact O-NE1 2.96Å; T222-W285 VanDerWaalsContact O-NE1 3.09Å
223	L	89.4	Confident	87.7	Confident	104 Å²	104	59.8 Å²	59.8	55%	0.545	31%	0.314	S	S	.	.	T	Hydrogen-bonded Turn	trans	-90.8	21.7	177.4	-59.2	178.8	0	0	0	112.7	D221 G225 L226 H227 W285	D221-L223 VanDerWaalsContact C-N 3.28Å; L223-G225 PolarHBondContact O-N 2.95Å; L223-G225 VanDerWaalsContact O-N 3.14Å; L223-L226 PolarHBondContact O-N 3.43Å; L223-H227 PolarHBondContact O-N 3.47Å; L223-H227 VanDerWaalsContact O-N 3.15Å; L223-W285 HydrophobicContact CD2-CH2 4.43Å; L223-W285 HydrophobicContact CD2-CZ2 3.85Å
224	F	88.3	Confident	87.4	Confident	4 Å²	4	66.4 Å²	66.4	2%	0.018	35%	0.348	C	S	.	.	H	α-helix	trans	-54.1	-36.9	-177.6	75.6	-90.8	0	0	0	112.7	M213 K214 I217 T219 T222 L226 H227 V228 W285	M213-F224 HydrophobicContact CB-CE1 4.17Å; M213-F224 HydrophobicContact CB-CZ 3.87Å; M213-F224 HydrophobicContact CE-CZ 3.89Å; K214-F224 HydrophobicContact CB-CD1 4.41Å; K214-F224 HydrophobicContact CB-CE1 4.37Å; I217-F224 HydrophobicContact CD1-CD2 3.69Å; I217-F224 HydrophobicContact CD1-CE1 4.48Å; I217-F224 HydrophobicContact CD1-CE2 3.34Å; I217-F224 HydrophobicContact CD1-CG 4.41Å; I217-F224 HydrophobicContact CD1-CZ 3.79Å; T219-F224 HydrophobicContact CG2-CB 3.7Å; T219-F224 HydrophobicContact CG2-CD1 4.22Å; T219-F224 HydrophobicContact CG2-CG 4.01Å; T222-F224 VanDerWaalsContact C-N 3.27Å; T222-F224 PolarHBondContact O-N 3.22Å; F224-L226 VanDerWaalsContact C-N 3.3Å; F224-L226 PolarHBondContact O-N 2.92Å; F224-H227 PolarHBondContact O-N 3.21Å; F224-V228 VanDerWaalsContact O-CG2 3.31Å; F224-V228 WeakPolarHBondContact O-CG2 3.3Å; F224-V228 PolarHBondContact O-N 3.22Å; F224-W285 AromaticContact CE1-CD1 3.57Å; F224-W285 HydrophobicContact CZ-CB 4.41Å; F224-W285 AromaticContact CZ-CD1 3.68Å; F224-W285 HydrophobicContact CZ-CG 4.35Å
225	G	88.2	Confident	86.9	Confident	0 Å²	0	67.2 Å²	67.2	0%	0	37%	0.367	C	S	.	.	H	α-helix	trans	-64.2	-34.9	179.8	0	0	0	0	0	113	L223 F229	L223-G225 PolarHBondContact O-N 2.95Å; L223-G225 VanDerWaalsContact O-N 3.14Å; G225-F229 VanDerWaalsContact O-CB 3.22Å; G225-F229 WeakPolarHBondContact O-CB 2.88Å; G225-F229 PolarHBondContact O-N 2.98Å; G225-F229 VanDerWaalsContact O-N 3.14Å
226	L	90	Very high	85.9	Confident	62 Å²	62	63 Å²	63	33%	0.325	35%	0.354	S	S	.	.	H	α-helix	trans	-71.5	-42.3	174.1	-178.1	63	0	0	0	111.3	L223 F224 F229 Q230 W285	L223-L226 PolarHBondContact O-N 3.43Å; F224-L226 VanDerWaalsContact C-N 3.3Å; F224-L226 PolarHBondContact O-N 2.92Å; L226-F229 PolarHBondContact O-N 3.41Å; L226-Q230 HydrophobicContact CD1-CG 4.4Å; L226-Q230 VanDerWaalsContact O-CG 3.31Å; L226-Q230 WeakPolarHBondContact O-CG 3.43Å; L226-Q230 PolarHBondContact O-N 3.47Å; L226-W285 HydrophobicContact CB-CH2 3.8Å; L226-W285 HydrophobicContact CB-CZ2 4.41Å; L226-W285 HydrophobicContact CB-CZ3 4.13Å
227	H	88.1	Confident	84.9	Confident	79 Å²	79	66.9 Å²	66.9	37%	0.366	37%	0.372	S	S	.	.	H	α-helix	trans	-61.9	-51.4	179.6	-175	53.9	0	0	0	111.6	L223 F224 F229 Q230 E231	L223-H227 PolarHBondContact O-N 3.47Å; L223-H227 VanDerWaalsContact O-N 3.15Å; F224-H227 PolarHBondContact O-N 3.21Å; H227-F229 VanDerWaalsContact C-N 3.27Å; H227-F229 PolarHBondContact O-N 3.32Å; H227-Q230 PolarHBondContact O-N 2.63Å; H227-Q230 VanDerWaalsContact O-N 3.13Å; H227-E231 IonicContact CD2-OE1 3.64Å; H227-E231 IonicContact CE1-OE1 3.12Å; H227-E231 PolarHBondContact CE1-OE1 3.05Å; H227-E231 IonicContact NE2-OE1 3.76Å; H227-E231 PolarHBondContact NE2-OE1 3.5Å; H227-E231 VanDerWaalsContact NE2-OE1 3.12Å; H227-E231 WeakPolarHBondContact O-CG 3.46Å; H227-E231 PolarHBondContact O-N 3.44Å
228	V	87.6	Confident	84.2	Confident	7 Å²	7	68.5 Å²	68.5	4%	0.042	38%	0.378	C	S	.	.	H	α-helix	trans	-61.4	-37.8	177.1	-179.3	0	0	0	0	111	F224 E231 L232 L243 E278 I282	F224-V228 VanDerWaalsContact O-CG2 3.31Å; F224-V228 WeakPolarHBondContact O-CG2 3.3Å; F224-V228 PolarHBondContact O-N 3.22Å; V228-E231 PolarHBondContact O-N 3.48Å; V228-L232 HydrophobicContact CG1-CD1 4.47Å; V228-L232 VanDerWaalsContact O-CG 3.3Å; V228-L232 WeakPolarHBondContact O-CG 3.33Å; V228-L232 PolarHBondContact O-N 2.94Å; V228-L243 HydrophobicContact CG2-CD1 4.18Å; V228-E278 HydrophobicContact CG1-CG 4.24Å; V228-I282 HydrophobicContact CB-CD1 4.42Å; V228-I282 HydrophobicContact CB-CG1 4.38Å; V228-I282 HydrophobicContact CG1-CD1 3.65Å; V228-I282 HydrophobicContact CG1-CG1 4.04Å
229	F	89.5	Confident	83.5	Confident	81 Å²	81	69 Å²	69	36%	0.355	37%	0.368	S	S	.	.	H	α-helix	trans	-65.1	-40.4	176	-177.5	-105.4	0	0	0	112.8	G225 L226 H227 L232 L233 I282 F286	G225-F229 VanDerWaalsContact O-CB 3.22Å; G225-F229 WeakPolarHBondContact O-CB 2.88Å; G225-F229 PolarHBondContact O-N 2.98Å; G225-F229 VanDerWaalsContact O-N 3.14Å; L226-F229 PolarHBondContact O-N 3.41Å; H227-F229 VanDerWaalsContact C-N 3.27Å; H227-F229 PolarHBondContact O-N 3.32Å; F229-L232 PolarHBondContact O-N 3.2Å; F229-L233 HydrophobicContact CD1-CD1 4.01Å; F229-L233 HydrophobicContact CE1-CD1 3.5Å; F229-L233 HydrophobicContact CE1-CG 4.18Å; F229-L233 HydrophobicContact CZ-CD1 3.96Å; F229-L233 HydrophobicContact CZ-CD2 4.36Å; F229-L233 HydrophobicContact CZ-CG 4.25Å; F229-L233 WeakPolarHBondContact O-CG 3.46Å; F229-L233 PolarHBondContact O-N 3.38Å; F229-L233 VanDerWaalsContact O-N 3.14Å; F229-I282 HydrophobicContact CB-CG2 4.37Å; F229-I282 HydrophobicContact CD2-CG2 4.24Å; F229-F286 HydrophobicContact CB-CE2 4.11Å; F229-F286 HydrophobicContact CB-CZ 4.18Å; F229-F286 HydrophobicContact CD1-CE2 4.49Å; F229-F286 HydrophobicContact CD1-CZ 4.07Å; F229-F286 HydrophobicContact CD2-CE2 4.18Å; F229-F286 HydrophobicContact CG-CE2 4.01Å; F229-F286 HydrophobicContact CG-CZ 4.01Å
230	Q	88.3	Confident	82.9	Confident	94 Å²	94	73.3 Å²	73.3	44%	0.439	39%	0.394	S	S	.	.	H	α-helix	trans	-66	-43	175.8	-74	172.8	-20.2	0	0	111.8	L226 H227 L232 L233 I234	L226-Q230 HydrophobicContact CD1-CG 4.4Å; L226-Q230 VanDerWaalsContact O-CG 3.31Å; L226-Q230 WeakPolarHBondContact O-CG 3.43Å; L226-Q230 PolarHBondContact O-N 3.47Å; H227-Q230 PolarHBondContact O-N 2.63Å; H227-Q230 VanDerWaalsContact O-N 3.13Å; Q230-L232 VanDerWaalsContact C-N 3.27Å; Q230-L232 PolarHBondContact O-N 3.41Å; Q230-L233 PolarHBondContact O-N 2.78Å; Q230-L233 VanDerWaalsContact O-N 3.17Å; Q230-I234 WeakPolarHBondContact O-CG1 3.24Å; Q230-I234 PolarHBondContact O-N 3.29Å
231	E	84.3	Confident	82.4	Confident	31 Å²	31	68.2 Å²	68.2	15%	0.145	37%	0.369	C	S	.	.	H	α-helix	trans	-58.1	-41.2	175	-71.3	-176.7	158.6	0	0	111.6	H227 V228 L233 I234 G235 S236 S241	H227-E231 IonicContact CD2-OE1 3.64Å; H227-E231 IonicContact CE1-OE1 3.12Å; H227-E231 PolarHBondContact CE1-OE1 3.05Å; H227-E231 IonicContact NE2-OE1 3.76Å; H227-E231 PolarHBondContact NE2-OE1 3.5Å; H227-E231 VanDerWaalsContact NE2-OE1 3.12Å; H227-E231 WeakPolarHBondContact O-CG 3.46Å; H227-E231 PolarHBondContact O-N 3.44Å; V228-E231 PolarHBondContact O-N 3.48Å; E231-L233 PolarHBondContact O-N 3.34Å; E231-I234 PolarHBondContact O-N 3.5Å; E231-G235 PolarHBondContact O-N 3.12Å; E231-S236 PolarHBondContact O-N 2.85Å; E231-S241 PolarHBondContact OE2-OG 3.38Å
232	L	85.5	Confident	82	Confident	62 Å²	62	64.3 Å²	64.3	33%	0.325	35%	0.351	S	S	.	.	H	α-helix	trans	-65.2	-36	176	-75	174	0	0	0	114	V228 F229 Q230 G235 E278 K279 I282	V228-L232 HydrophobicContact CG1-CD1 4.47Å; V228-L232 VanDerWaalsContact O-CG 3.3Å; V228-L232 WeakPolarHBondContact O-CG 3.33Å; V228-L232 PolarHBondContact O-N 2.94Å; F229-L232 PolarHBondContact O-N 3.2Å; Q230-L232 VanDerWaalsContact C-N 3.27Å; Q230-L232 PolarHBondContact O-N 3.41Å; L232-G235 PolarHBondContact O-N 2.87Å; L232-E278 WeakPolarHBondContact CD1-OE1 3.39Å; L232-E278 WeakPolarHBondContact CD2-OE1 3.32Å; L232-K279 VanDerWaalsContact CD2-NZ 3.3Å; L232-I282 HydrophobicContact CD1-CD1 3.45Å; L232-I282 VanDerWaalsContact CD1-CD1 3.45Å
233	L	87.2	Confident	81.8	Confident	128 Å²	128	61.6 Å²	61.6	67%	0.67	33%	0.333	S	S	*	.	H	α-helix	trans	-71.5	-36.7	177.3	-73.4	175.8	0	0	0	112.3	F229 Q230 E231 G235	F229-L233 HydrophobicContact CD1-CD1 4.01Å; F229-L233 HydrophobicContact CE1-CD1 3.5Å; F229-L233 HydrophobicContact CE1-CG 4.18Å; F229-L233 HydrophobicContact CZ-CD1 3.96Å; F229-L233 HydrophobicContact CZ-CD2 4.36Å; F229-L233 HydrophobicContact CZ-CG 4.25Å; F229-L233 WeakPolarHBondContact O-CG 3.46Å; F229-L233 PolarHBondContact O-N 3.38Å; F229-L233 VanDerWaalsContact O-N 3.14Å; Q230-L233 PolarHBondContact O-N 2.78Å; Q230-L233 VanDerWaalsContact O-N 3.17Å; E231-L233 PolarHBondContact O-N 3.34Å; L233-G235 PolarHBondContact O-N 3.31Å
234	I	86.9	Confident	81.7	Confident	139 Å²	139	56.9 Å²	56.9	71%	0.713	31%	0.308	S	S	*	.	H	α-helix	trans	-71.8	-22.4	176.3	-65.4	165.5	0	0	0	110.6	Q230 E231 S236	Q230-I234 WeakPolarHBondContact O-CG1 3.24Å; Q230-I234 PolarHBondContact O-N 3.29Å; E231-I234 PolarHBondContact O-N 3.5Å; I234-S236 VanDerWaalsContact C-N 3.34Å
235	G	80.3	Confident	81.8	Confident	57 Å²	57	56.8 Å²	56.8	59%	0.588	31%	0.308	S	S	*	.	T	Hydrogen-bonded Turn	trans	78.1	21.3	-174	0	0	0	0	0	112.6	E231 L232 L233	E231-G235 PolarHBondContact O-N 3.12Å; L232-G235 PolarHBondContact O-N 2.87Å; L233-G235 PolarHBondContact O-N 3.31Å
236	S	71.1	Confident	81.9	Confident	54 Å²	54	60.9 Å²	60.9	38%	0.378	32%	0.324	S	S	.	.			trans	-65.4	139.2	174.4	-173.8	0	0	0	0	110	E231 I234	E231-S236 PolarHBondContact O-N 2.85Å; I234-S236 VanDerWaalsContact C-N 3.34Å
237	E	67.9	Low	81.9	Confident	121 Å²	121	59.4 Å²	59.4	57%	0.565	32%	0.317	S	S	*	.			trans	-75.6	146.7	179.5	-68.2	176.4	162.8	0	0	111.5	E239 V240	E237-E239 HydrophobicContact CB-CB 4.45Å; E237-E239 HydrophobicContact CB-CG 4.26Å; E237-E239 PolarHBondContact O-N 3.47Å; E237-V240 PolarHBondContact O-N 3.39Å
238	W	72.9	Confident	82.2	Confident	39 Å²	39	55.7 Å²	55.7	15%	0.148	30%	0.3	C	S	.	.	H	α-helix	trans	-60.1	-12.8	176.1	54.4	-85.1	0	0	0	113.3	F81 V240 G242 P245 R246 V247	F81-W238 HydrophobicContact CD2-CZ3 4.19Å; F81-W238 HydrophobicContact CE2-CE3 4.11Å; F81-W238 AromaticContact CE2-CZ3 3.61Å; F81-W238 HydrophobicContact CE2-CZ3 3.61Å; W238-V240 VanDerWaalsContact C-N 3.28Å; W238-V240 PolarHBondContact O-N 3.05Å; W238-G242 PolarHBondContact O-N 3.09Å; W238-P245 HydrophobicContact CE3-CB 3.66Å; W238-P245 HydrophobicContact CZ3-CB 3.71Å; W238-R246 HydrophobicContact CD2-CB 4.13Å; W238-R246 HydrophobicContact CD2-CG 4.1Å; W238-R246 HydrophobicContact CG-CG 4.05Å; W238-R246 HydrophobicContact CZ2-CB 4.01Å; W238-V247 HydrophobicContact CH2-CB 3.6Å; W238-V247 HydrophobicContact CH2-CG2 3.77Å; W238-V247 HydrophobicContact CZ2-CB 4.24Å; W238-V247 HydrophobicContact CZ2-CG2 3.88Å; W238-V247 HydrophobicContact CZ3-CB 4.41Å
239	E	69.2	Low	82.4	Confident	60 Å²	60	57.7 Å²	57.7	28%	0.28	31%	0.307	S	S	.	.	H	α-helix	trans	-66.8	-26.2	-177.1	-59.2	-172.2	173.9	0	0	113.2	P84 E237	P84-E239 HydrophobicContact CG-CB 3.87Å; P84-E239 HydrophobicContact CG-CG 4.3Å; P84-E239 WeakPolarHBondContact CG-OE2 3.43Å; E237-E239 HydrophobicContact CB-CB 4.45Å; E237-E239 HydrophobicContact CB-CG 4.26Å; E237-E239 PolarHBondContact O-N 3.47Å
240	V	70.4	Confident	82.6	Confident	109 Å²	109	54 Å²	54	66%	0.661	29%	0.291	S	S	*	.	H	α-helix	trans	-86.7	-45	-176.3	-176.6	0	0	0	0	112	E237 W238	E237-V240 PolarHBondContact O-N 3.39Å; W238-V240 VanDerWaalsContact C-N 3.28Å; W238-V240 PolarHBondContact O-N 3.05Å
241	S	74	Confident	82.8	Confident	33 Å²	33	50.7 Å²	50.7	23%	0.231	28%	0.276	C	S	.	.	H	α-helix	trans	-80.1	-21.7	-176.2	62.1	0	0	0	0	112.7	E231 L243	E231-S241 PolarHBondContact OE2-OG 3.38Å; S241-L243 PolarHBondContact O-N 3.46Å
242	G	76.9	Confident	83.1	Confident	10 Å²	10	49.3 Å²	49.3	10%	0.103	27%	0.27	C	S	.	.			trans	61.1	10.8	-173.2	0	0	0	0	0	113.2	F81 W238	F81-G242 VanDerWaalsContact CE1-CA 3.44Å; W238-G242 PolarHBondContact O-N 3.09Å
243	L	81.9	Confident	83.2	Confident	20 Å²	20	51.6 Å²	51.6	11%	0.105	28%	0.277	C	S	.	.	S	Bend	trans	-89	127	174.5	-66.6	170.2	0	0	0	107.8	I217 V228 S241	I217-L243 HydrophobicContact CG2-CD2 3.61Å; V228-L243 HydrophobicContact CG2-CD1 4.18Å; S241-L243 PolarHBondContact O-N 3.46Å
244	F	87.8	Confident	83.3	Confident	5 Å²	5	46.6 Å²	46.6	2%	0.022	25%	0.252	C	S	.	.	S	Bend	trans	54.5	56.4	-178.5	-51.9	-76.8	0	0	0	115.2	Y103 I217 N274 I277 E278 Y281	Y103-F244 HydrophobicContact CE2-CD1 4.12Å; Y103-F244 HydrophobicContact CE2-CE1 4.23Å; Y103-F244 WeakPolarHBondContact OH-CA 3.38Å; I217-F244 HydrophobicContact CD1-CE2 4.23Å; I217-F244 HydrophobicContact CD1-CZ 3.62Å; I217-F244 HydrophobicContact CG1-CE1 4.39Å; I217-F244 HydrophobicContact CG1-CZ 3.86Å; I217-F244 HydrophobicContact CG2-CZ 4.5Å; F244-N274 WeakPolarHBondContact CA-ND2 3.49Å; F244-N274 WeakPolarHBondContact CD1-OD1 3.47Å; F244-I277 HydrophobicContact CD1-CG2 4.2Å; F244-I277 HydrophobicContact CE1-CG2 3.74Å; F244-E278 HydrophobicContact CB-CB 3.92Å; F244-E278 HydrophobicContact CB-CG 3.87Å; F244-E278 HydrophobicContact CD1-CB 4.14Å; F244-E278 HydrophobicContact CD2-CB 4.18Å; F244-E278 HydrophobicContact CD2-CG 3.75Å; F244-E278 HydrophobicContact CE2-CG 4.42Å; F244-E278 HydrophobicContact CG-CB 3.82Å; F244-E278 HydrophobicContact CG-CG 3.82Å; F244-Y281 HydrophobicContact CZ-CG 4.3Å
245	P	89.6	Confident	83.2	Confident	1 Å²	1	50.4 Å²	50.4	1%	0.006	26%	0.258	C	S	.	.			trans	-66.5	138.7	-178	27.4	-33.9	0	0	0	113.3	F81 I101 W238 T248 N274	F81-P245 HydrophobicContact CB-CB 4.4Å; F81-P245 HydrophobicContact CB-CG 4.08Å; F81-P245 HydrophobicContact CD2-CB 3.44Å; F81-P245 VanDerWaalsContact CD2-CB 3.44Å; F81-P245 HydrophobicContact CD2-CG 4.05Å; F81-P245 HydrophobicContact CE2-CB 3.92Å; F81-P245 HydrophobicContact CG-CB 4.01Å; F81-P245 HydrophobicContact CG-CG 4.13Å; I101-P245 HydrophobicContact CD1-CG 3.22Å; W238-P245 HydrophobicContact CE3-CB 3.66Å; W238-P245 HydrophobicContact CZ3-CB 3.71Å; P245-T248 HydrophobicContact CB-CG2 4.34Å; P245-T248 HydrophobicContact CG-CG2 4.05Å; P245-N274 WeakPolarHBondContact CD-ND2 3.14Å; P245-N274 PolarHBondContact O-ND2 2.89Å
246	R	90.2	Very high	83.4	Confident	87 Å²	87	52.4 Å²	52.4	33%	0.328	25%	0.25	S	C	.	.	S	Bend	trans	-89.8	-24.2	-179.2	-59	-177	-173.7	165.7	4.1	112.2	W238 V270 L271 E278	W238-R246 HydrophobicContact CD2-CB 4.13Å; W238-R246 HydrophobicContact CD2-CG 4.1Å; W238-R246 HydrophobicContact CG-CG 4.05Å; W238-R246 HydrophobicContact CZ2-CB 4.01Å; R246-V270 CarbonylContact O-C 3.59Å; R246-V270 WeakPolarHBondContact O-CA 3.46Å; R246-L271 PolarHBondContact O-N 2.91Å; R246-E278 IonicContact NH2-OE2 2.87Å
247	V	91.3	Very high	84.1	Confident	31 Å²	31	58.7 Å²	58.7	19%	0.188	28%	0.278	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-119.9	133.9	173.7	-172.3	0	0	0	0	108.6	W238 Q268 C269	W238-V247 HydrophobicContact CH2-CB 3.6Å; W238-V247 HydrophobicContact CH2-CG2 3.77Å; W238-V247 HydrophobicContact CZ2-CB 4.24Å; W238-V247 HydrophobicContact CZ2-CG2 3.88Å; W238-V247 HydrophobicContact CZ3-CB 4.41Å; V247-Q268 HydrophobicContact CG1-CG 3.45Å; V247-Q268 VanDerWaalsContact CG1-CG 3.45Å; V247-C269 CarbonylContact C-O 3.53Å; V247-C269 WeakPolarHBondContact CA-O 3.43Å
248	T	92.7	Very high	84.9	Confident	0 Å²	0	57 Å²	57	0%	0	29%	0.293	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-138.3	159.4	-179.1	57.3	0	0	0	0	109.4	T79 Y80 I101 P245 C269 L271	T79-T248 WeakPolarHBondContact CB-OG1 3.32Å; T79-T248 VanDerWaalsContact OG1-CB 3.28Å; T79-T248 WeakPolarHBondContact OG1-CB 3.44Å; T79-T248 PolarHBondContact OG1-OG1 3.27Å; T79-T248 VanDerWaalsContact OG1-OG1 3.07Å; Y80-T248 WeakPolarHBondContact O-CA 3.48Å; I101-T248 HydrophobicContact CD1-CG2 4.02Å; P245-T248 HydrophobicContact CB-CG2 4.34Å; P245-T248 HydrophobicContact CG-CG2 4.05Å; T248-C269 PolarHBondContact N-O 3.36Å; T248-C269 PolarHBondContact O-N 3.41Å; T248-C269 VanDerWaalsContact O-O 3.13Å; T248-L271 HydrophobicContact CG2-CD2 4.44Å
249	Y	93.2	Very high	85.2	Confident	50 Å²	50	59.9 Å²	59.9	20%	0.196	31%	0.308	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-108.9	153.2	179.7	-62.7	-88.1	0	0	0	110.8	T79 Y80 L82 L267 Q268	T79-Y249 WeakPolarHBondContact CA-O 3.26Å; T79-Y249 WeakPolarHBondContact CB-O 3.49Å; Y80-Y249 WeakPolarHBondContact CD1-O 3.32Å; Y80-Y249 VanDerWaalsContact CE2-CB 3.46Å; Y80-Y249 HydrophobicContact CE2-CG 4.32Å; Y80-Y249 PolarHBondContact N-O 3.3Å; Y80-Y249 PolarHBondContact O-N 3.21Å; L82-Y249 HydrophobicContact CB-CD2 3.99Å; L82-Y249 HydrophobicContact CB-CE2 3.85Å; L82-Y249 HydrophobicContact CD1-CD2 3.76Å; L82-Y249 HydrophobicContact CD1-CE2 3.97Å; L82-Y249 HydrophobicContact CD1-CG 4.17Å; L82-Y249 HydrophobicContact CG-CD2 3.83Å; L82-Y249 HydrophobicContact CG-CE2 4.15Å; Y249-L267 WeakPolarHBondContact CA-O 3.33Å; Y249-Q268 HydrophobicContact CD1-CB 4.24Å; Y249-Q268 HydrophobicContact CD1-CG 4.41Å; Y249-Q268 HydrophobicContact CE1-CB 3.99Å; Y249-Q268 HydrophobicContact CE1-CG 3.88Å
250	C	93.4	Very high	85.9	Confident	2 Å²	2	65.8 Å²	65.8	1%	0.014	34%	0.341	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-149.4	139.1	-178.5	169.5	0	0	0	0	110.6	C74 T79 L267	C74-C250 WeakPolarHBondContact CA-SG 3.25Å; C74-C250 HydrophobicContact CB-CB 3.66Å; C74-C250 WeakPolarHBondContact CB-SG 3.47Å; C74-C250 WeakPolarHBondContact SG-CB 3.46Å; C74-C250 CovalentContact SG-SG 2.03Å; C74-C250 PolarHBondContact SG-SG 3.18Å; T79-C250 HydrophobicContact CG2-CB 4.23Å; C250-L267 PolarHBondContact N-O 3.45Å; C250-L267 PolarHBondContact O-N 3.49Å
251	D	91.5	Very high	86.3	Confident	25 Å²	25	69 Å²	69	13%	0.134	35%	0.346	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-110.2	112.2	-178.4	-54.1	-30.1	0	0	0	111.1	Y80 M95 Y265 T266	Y80-D251 WeakPolarHBondContact CE1-OD2 3.49Å; Y80-D251 PolarHBondContact OH-OD1 3.49Å; Y80-D251 PolarHBondContact OH-OD2 2.85Å; M95-D251 VanDerWaalsContact SD-OD2 3.33Å; D251-Y265 WeakPolarHBondContact CA-O 3.3Å; D251-T266 WeakPolarHBondContact OD1-CG2 3.46Å
252	V	91	Very high	86.7	Confident	3 Å²	3	69.7 Å²	69.7	2%	0.018	35%	0.35	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.3	114.4	178.3	-176.3	0	0	0	0	109.5	A70 I73 V254 S264 Y265 L267	A70-V252 HydrophobicContact CB-CG2 4.32Å; I73-V252 HydrophobicContact CG2-CG2 4.39Å; V252-V254 HydrophobicContact CG1-CG2 3.92Å; V252-S264 WeakPolarHBondContact O-CA 3.28Å; V252-Y265 PolarHBondContact N-O 3.42Å; V252-Y265 PolarHBondContact O-N 3.44Å; V252-L267 HydrophobicContact CG2-CD1 3.72Å; V252-L267 HydrophobicContact CG2-CG 4.41Å
253	K	89	Confident	87.1	Confident	109 Å²	109	70.3 Å²	70.3	47%	0.474	35%	0.354	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.2	106.8	176.8	-63.9	-175.6	178.4	179.3	0	110.4	D92 P262 A263	D92-K253 IonicContact OD1-NZ 3.44Å; K253-P262 HydrophobicContact CB-CB 4.35Å; K253-A263 CarbonylContact C-O 3.59Å; K253-A263 WeakPolarHBondContact CA-O 3.37Å
254	V	87.4	Confident	87.3	Confident	24 Å²	24	72.8 Å²	72.8	15%	0.145	37%	0.373	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-103	130.7	179.6	-174.8	0	0	0	0	110.5	V252 P262 A263 Y265	V252-V254 HydrophobicContact CG1-CG2 3.92Å; V254-P262 WeakPolarHBondContact O-CA 3.42Å; V254-A263 PolarHBondContact N-O 2.89Å; V254-A263 PolarHBondContact O-N 2.78Å; V254-Y265 HydrophobicContact CG2-CD2 4.43Å; V254-Y265 HydrophobicContact CG2-CE2 4.49Å
255	R	86	Confident	87.5	Confident	219 Å²	219	75.4 Å²	75.4	83%	0.826	38%	0.383	S	S	*	.	P	Polyproline II helix	trans	-102.7	117.2	173.5	-68.8	-176.2	178	115	-1.3	110	P262	R255-P262 HydrophobicContact CG-CB 3.92Å
256	K	84.4	Confident	87.6	Confident	98 Å²	98	78.7 Å²	78.7	43%	0.426	40%	0.403	S	S	.	.	P	Polyproline II helix	trans	-99.7	148.6	168.8	-56	179.6	179.3	177.7	0	109.7	G258 Q259	K256-G258 PolarHBondContact O-N 2.78Å; K256-Q259 HydrophobicContact CB-CG 4.44Å; K256-Q259 PolarHBondContact O-N 3.34Å
257	L	84.6	Confident	87.8	Confident	186 Å²	186	74.6 Å²	74.6	97%	0.974	39%	0.388	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.4	134.1	175.5	-73.1	165.8	0	0	0	110.1
258	G	85.8	Confident	87.9	Confident	85 Å²	85	76.6 Å²	76.6	88%	0.876	40%	0.395	S	S	*	.	T	Hydrogen-bonded Turn	trans	87.4	-7	179.4	0	0	0	0	0	115.9	K256	K256-G258 PolarHBondContact O-N 2.78Å
259	Q	80.1	Confident	88	Confident	100 Å²	100	76.6 Å²	76.6	47%	0.467	40%	0.395	S	S	.	.			trans	-90.8	128.5	174.1	-66.7	-174.1	-56	0	0	111.4	K256	K256-Q259 HydrophobicContact CB-CG 4.44Å; K256-Q259 PolarHBondContact O-N 3.34Å
260	L	82	Confident	88	Confident	184 Å²	184	77.7 Å²	77.7	96%	0.963	41%	0.407	S	S	*	.	S	Bend	trans	-69.9	-31.6	177.5	-124.3	105.8	0	0	0	112.7
261	K	80	Confident	87.9	Confident	177 Å²	177	77.7 Å²	77.7	77%	0.77	41%	0.407	S	S	*	.	S	Bend	trans	-119.4	142.9	178.5	-67.8	-172.9	179.2	-176.1	0	110.2
262	P	82.7	Confident	87.9	Confident	48 Å²	48	77.9 Å²	77.9	31%	0.312	41%	0.409	S	S	.	.			trans	-63.2	139.8	172.3	26.9	-32.2	0	0	0	110.4	K253 V254 R255 S264	K253-P262 HydrophobicContact CB-CB 4.35Å; V254-P262 WeakPolarHBondContact O-CA 3.42Å; R255-P262 HydrophobicContact CG-CB 3.92Å; P262-S264 PolarHBondContact O-N 3.26Å
263	A	84.7	Confident	87.9	Confident	23 Å²	23	78 Å²	78	19%	0.19	41%	0.41	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-73.2	124.3	167.7	0	0	0	0	0	108.3	K253 V254 Y265	K253-A263 CarbonylContact C-O 3.59Å; K253-A263 WeakPolarHBondContact CA-O 3.37Å; V254-A263 PolarHBondContact N-O 2.89Å; V254-A263 PolarHBondContact O-N 2.78Å; A263-Y265 HydrophobicContact CB-CE2 3.85Å
264	S	86.9	Confident	87.9	Confident	71 Å²	71	72.8 Å²	72.8	50%	0.497	39%	0.387	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-105.7	129.6	179.1	-53.4	0	0	0	0	108.9	V252 P262	V252-S264 WeakPolarHBondContact O-CA 3.28Å; P262-S264 PolarHBondContact O-N 3.26Å
265	Y	90.4	Very high	88	Confident	60 Å²	60	76.7 Å²	76.7	24%	0.235	40%	0.4	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-119.7	118.9	177.1	-63.7	-87.1	0	0	0	108.9	P59 F62 D251 V252 V254 A263	P59-Y265 HydrophobicContact CG-CD1 4.07Å; P59-Y265 HydrophobicContact CG-CE1 4.43Å; F62-Y265 HydrophobicContact CE1-CD1 4.34Å; F62-Y265 HydrophobicContact CE1-CE1 4.09Å; F62-Y265 HydrophobicContact CE1-CE2 4.29Å; F62-Y265 HydrophobicContact CZ-CD1 4.26Å; F62-Y265 AromaticContact CZ-CD2 3.98Å; F62-Y265 HydrophobicContact CZ-CD2 3.98Å; F62-Y265 HydrophobicContact CZ-CE1 4.38Å; F62-Y265 HydrophobicContact CZ-CE2 4.12Å; F62-Y265 HydrophobicContact CZ-CG 4.05Å; D251-Y265 WeakPolarHBondContact CA-O 3.3Å; V252-Y265 PolarHBondContact N-O 3.42Å; V252-Y265 PolarHBondContact O-N 3.44Å; V254-Y265 HydrophobicContact CG2-CD2 4.43Å; V254-Y265 HydrophobicContact CG2-CE2 4.49Å; A263-Y265 HydrophobicContact CB-CE2 3.85Å
266	T	92	Very high	88.2	Confident	70 Å²	70	70.8 Å²	70.8	43%	0.429	38%	0.381	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-87	111.9	173.1	53.9	0	0	0	0	108.7	I88 D251	I88-T266 HydrophobicContact CG2-CG2 3.78Å; D251-T266 WeakPolarHBondContact OD1-CG2 3.46Å
267	L	94	Very high	88.6	Confident	2 Å²	2	66.1 Å²	66.1	1%	0.01	36%	0.36	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-103.8	134.2	-177	-55.4	-179.4	0	0	0	110.1	C56 V58 A70 Y249 C250 V252	C56-L267 HydrophobicContact CB-CB 4.33Å; C56-L267 HydrophobicContact CB-CD1 4.4Å; V58-L267 HydrophobicContact CG1-CD1 4.16Å; V58-L267 HydrophobicContact CG1-CD2 4.25Å; A70-L267 HydrophobicContact CB-CD1 3.72Å; Y249-L267 WeakPolarHBondContact CA-O 3.33Å; C250-L267 PolarHBondContact N-O 3.45Å; C250-L267 PolarHBondContact O-N 3.49Å; V252-L267 HydrophobicContact CG2-CD1 3.72Å; V252-L267 HydrophobicContact CG2-CG 4.41Å
268	Q	93.9	Very high	88.9	Confident	72 Å²	72	57.7 Å²	57.7	34%	0.336	32%	0.316	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-89.8	119.1	171	-173.1	-179.2	13.6	0	0	108.8	W57 V247 Y249	W57-Q268 PolarHBondContact N-O 2.92Å; V247-Q268 HydrophobicContact CG1-CG 3.45Å; V247-Q268 VanDerWaalsContact CG1-CG 3.45Å; Y249-Q268 HydrophobicContact CD1-CB 4.24Å; Y249-Q268 HydrophobicContact CD1-CG 4.41Å; Y249-Q268 HydrophobicContact CE1-CB 3.99Å; Y249-Q268 HydrophobicContact CE1-CG 3.88Å
269	C	94.8	Very high	89.2	Confident	0 Å²	0	56.8 Å²	56.8	0%	0	29%	0.288	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.8	134.3	-172.5	-52.1	0	0	0	0	112.5	L54 H55 C56 V247 T248	L54-C269 HydrophobicContact CD1-CB 3.67Å; L54-C269 HydrophobicContact CD2-CB 3.65Å; L54-C269 HydrophobicContact CG-CB 3.73Å; H55-C269 CarbonylContact O-C 3.58Å; H55-C269 VanDerWaalsContact O-CA 3.23Å; H55-C269 WeakPolarHBondContact O-CA 3.29Å; C56-C269 HydrophobicContact CB-CB 4.05Å; C56-C269 WeakPolarHBondContact CB-SG 3.03Å; C56-C269 WeakPolarHBondContact SG-CB 3.36Å; C56-C269 CovalentContact SG-SG 2.04Å; C56-C269 PolarHBondContact SG-SG 2.89Å; V247-C269 CarbonylContact C-O 3.53Å; V247-C269 WeakPolarHBondContact CA-O 3.43Å; T248-C269 PolarHBondContact N-O 3.36Å; T248-C269 PolarHBondContact O-N 3.41Å; T248-C269 VanDerWaalsContact O-O 3.13Å
270	V	93.6	Very high	89.8	Confident	74 Å²	74	52.5 Å²	52.5	45%	0.448	27%	0.269	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-87.3	134.5	173.5	-177	0	0	0	0	109.1	L54 H55 R246 P272	L54-V270 WeakPolarHBondContact CA-O 3.31Å; L54-V270 VanDerWaalsContact CD1-O 3.23Å; L54-V270 WeakPolarHBondContact CD1-O 3.3Å; H55-V270 PolarHBondContact N-O 3.47Å; H55-V270 PolarHBondContact O-N 3.15Å; R246-V270 CarbonylContact O-C 3.59Å; R246-V270 WeakPolarHBondContact O-CA 3.46Å; V270-P272 HydrophobicContact CG1-CG 4.42Å; V270-P272 VanDerWaalsContact O-CD 3.24Å; V270-P272 WeakPolarHBondContact O-CD 3.35Å
271	L	91.9	Very high	90.4	Very high	1 Å²	1	43.8 Å²	43.8	1%	0.005	22%	0.223	C	C	.	.			trans	-117.9	79	-175	-171.5	65.5	0	0	0	111.9	L54 W75 Y104 R246 T248 V273 N274	L54-L271 HydrophobicContact CB-CD1 4.41Å; L54-L271 HydrophobicContact CD1-CB 3.84Å; L54-L271 HydrophobicContact CD1-CD1 3.53Å; L54-L271 HydrophobicContact CD1-CG 4.24Å; W75-L271 HydrophobicContact CE3-CD1 4.36Å; W75-L271 HydrophobicContact CZ3-CD1 3.75Å; Y104-L271 HydrophobicContact CD1-CD2 3.59Å; Y104-L271 HydrophobicContact CD2-CD1 4.33Å; Y104-L271 HydrophobicContact CE1-CD2 3.84Å; Y104-L271 HydrophobicContact CE2-CD1 4.38Å; Y104-L271 HydrophobicContact CG-CD1 4.42Å; Y104-L271 HydrophobicContact CG-CD2 4.08Å; R246-L271 PolarHBondContact O-N 2.91Å; T248-L271 HydrophobicContact CG2-CD2 4.44Å; L271-V273 VanDerWaalsContact C-N 3.27Å; L271-V273 PolarHBondContact O-N 3.43Å; L271-N274 HydrophobicContact CB-CB 4.43Å; L271-N274 HydrophobicContact CD2-CB 3.74Å; L271-N274 HydrophobicContact CG-CB 3.84Å; L271-N274 WeakPolarHBondContact O-CB 3.34Å; L271-N274 PolarHBondContact O-N 3.28Å
272	P	90.3	Very high	91	Very high	30 Å²	30	36.1 Å²	36.1	20%	0.195	19%	0.19	C	C	.	.	H	α-helix	trans	-61.8	-29.7	-179.1	-23.7	33.2	0	0	0	114.4	V270 N274 Y275 F276	V270-P272 HydrophobicContact CG1-CG 4.42Å; V270-P272 VanDerWaalsContact O-CD 3.24Å; V270-P272 WeakPolarHBondContact O-CD 3.35Å; P272-N274 PolarHBondContact O-N 2.71Å; P272-Y275 WeakPolarHBondContact O-CB 3.34Å; P272-Y275 PolarHBondContact O-N 3.48Å; P272-F276 WeakPolarHBondContact O-CD2 3.3Å
273	V	90.4	Very high	91.6	Very high	4 Å²	4	38.2 Å²	38.2	2%	0.024	20%	0.195	C	C	.	.	H	α-helix	trans	-59.1	-36.7	178.5	174	0	0	0	0	110.8	Q48 P53 W75 L271 Y275 F276 I277	Q48-V273 HydrophobicContact CG-CG2 4.12Å; P53-V273 HydrophobicContact CB-CG2 4Å; P53-V273 WeakPolarHBondContact O-CG2 3.31Å; W75-V273 HydrophobicContact CH2-CG2 4.36Å; L271-V273 VanDerWaalsContact C-N 3.27Å; L271-V273 PolarHBondContact O-N 3.43Å; V273-Y275 VanDerWaalsContact C-N 3.32Å; V273-Y275 PolarHBondContact O-N 3.31Å; V273-F276 PolarHBondContact O-N 3.41Å; V273-F276 VanDerWaalsContact O-N 3.15Å; V273-I277 HydrophobicContact CG1-CD1 3.89Å; V273-I277 HydrophobicContact CG1-CG1 4.28Å; V273-I277 WeakPolarHBondContact O-CG1 3.42Å; V273-I277 PolarHBondContact O-N 3.1Å
274	N	90.5	Very high	92.1	Very high	0 Å²	0	37.1 Å²	37.1	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-67	-34.8	-177.4	-154.3	21.2	0	0	0	112.9	Y103 F244 P245 L271 P272 F276 I277 E278	Y103-N274 WeakPolarHBondContact CE2-OD1 3.36Å; Y103-N274 VanDerWaalsContact CZ-OD1 3.3Å; Y103-N274 PolarHBondContact OH-ND2 3.34Å; Y103-N274 PolarHBondContact OH-OD1 3.41Å; F244-N274 WeakPolarHBondContact CA-ND2 3.49Å; F244-N274 WeakPolarHBondContact CD1-OD1 3.47Å; P245-N274 WeakPolarHBondContact CD-ND2 3.14Å; P245-N274 PolarHBondContact O-ND2 2.89Å; L271-N274 HydrophobicContact CB-CB 4.43Å; L271-N274 HydrophobicContact CD2-CB 3.74Å; L271-N274 HydrophobicContact CG-CB 3.84Å; L271-N274 WeakPolarHBondContact O-CB 3.34Å; L271-N274 PolarHBondContact O-N 3.28Å; P272-N274 PolarHBondContact O-N 2.71Å; N274-F276 VanDerWaalsContact C-N 3.27Å; N274-F276 PolarHBondContact O-N 3.39Å; N274-I277 PolarHBondContact O-N 3.03Å; N274-E278 WeakPolarHBondContact O-CB 3.34Å; N274-E278 PolarHBondContact O-N 2.83Å
275	Y	89.2	Confident	92.6	Very high	106 Å²	106	34.4 Å²	34.4	42%	0.416	16%	0.164	S	C	.	.	H	α-helix	trans	-57.2	-41.9	172.7	176.3	-92.7	0	0	0	111.6	P272 V273 K279	P272-Y275 WeakPolarHBondContact O-CB 3.34Å; P272-Y275 PolarHBondContact O-N 3.48Å; V273-Y275 VanDerWaalsContact C-N 3.32Å; V273-Y275 PolarHBondContact O-N 3.31Å; Y275-K279 WeakPolarHBondContact O-CG 3.49Å
276	F	90.4	Very high	92.8	Very high	96 Å²	96	35.4 Å²	35.4	42%	0.421	17%	0.17	S	C	.	.	H	α-helix	trans	-69	-43.9	175.6	-75.3	-81.2	0	0	0	111.9	R47 P272 V273 N274 E278 K279 V280	R47-F276 HydrophobicContact CG-CD2 4Å; R47-F276 HydrophobicContact CG-CE2 3.86Å; P272-F276 WeakPolarHBondContact O-CD2 3.3Å; V273-F276 PolarHBondContact O-N 3.41Å; V273-F276 VanDerWaalsContact O-N 3.15Å; N274-F276 VanDerWaalsContact C-N 3.27Å; N274-F276 PolarHBondContact O-N 3.39Å; F276-E278 VanDerWaalsContact C-N 3.29Å; F276-E278 PolarHBondContact O-N 3.06Å; F276-K279 PolarHBondContact O-N 2.9Å; F276-V280 WeakPolarHBondContact O-CG2 3.4Å; F276-V280 PolarHBondContact O-N 3.42Å
277	I	91.7	Very high	93	Very high	0 Å²	0	34.3 Å²	34.3	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-57	-45.4	178.7	-65.3	172.5	0	0	0	110.6	Y103 V107 F244 V273 N274 K279 V280 Y281	Y103-I277 HydrophobicContact CE2-CD1 4.43Å; Y103-I277 HydrophobicContact CE2-CG2 4.39Å; V107-I277 HydrophobicContact CB-CD1 4.04Å; V107-I277 HydrophobicContact CG1-CD1 3.76Å; V107-I277 HydrophobicContact CG1-CG1 4.17Å; V107-I277 HydrophobicContact CG2-CD1 4.17Å; V107-I277 HydrophobicContact CG2-CG1 4.17Å; V107-I277 HydrophobicContact CG2-CG2 4.09Å; F244-I277 HydrophobicContact CD1-CG2 4.2Å; F244-I277 HydrophobicContact CE1-CG2 3.74Å; V273-I277 HydrophobicContact CG1-CD1 3.89Å; V273-I277 HydrophobicContact CG1-CG1 4.28Å; V273-I277 WeakPolarHBondContact O-CG1 3.42Å; V273-I277 PolarHBondContact O-N 3.1Å; N274-I277 PolarHBondContact O-N 3.03Å; I277-K279 VanDerWaalsContact C-N 3.3Å; I277-K279 PolarHBondContact O-N 3.25Å; I277-V280 PolarHBondContact O-N 3Å; I277-Y281 HydrophobicContact CG2-CD2 3.56Å; I277-Y281 HydrophobicContact CG2-CE2 3.68Å; I277-Y281 HydrophobicContact CG2-CG 4.45Å; I277-Y281 WeakPolarHBondContact O-CB 3.47Å; I277-Y281 WeakPolarHBondContact O-CD2 3.46Å; I277-Y281 PolarHBondContact O-N 3.43Å
278	E	91.7	Very high	93.1	Very high	9 Å²	9	34.2 Å²	34.2	4%	0.042	16%	0.158	C	C	.	.	H	α-helix	trans	-49.5	-50.7	176.5	-167.9	-156	141.1	0	0	111.1	V228 L232 F244 R246 N274 F276 Y281 I282	V228-E278 HydrophobicContact CG1-CG 4.24Å; L232-E278 WeakPolarHBondContact CD1-OE1 3.39Å; L232-E278 WeakPolarHBondContact CD2-OE1 3.32Å; F244-E278 HydrophobicContact CB-CB 3.92Å; F244-E278 HydrophobicContact CB-CG 3.87Å; F244-E278 HydrophobicContact CD1-CB 4.14Å; F244-E278 HydrophobicContact CD2-CB 4.18Å; F244-E278 HydrophobicContact CD2-CG 3.75Å; F244-E278 HydrophobicContact CE2-CG 4.42Å; F244-E278 HydrophobicContact CG-CB 3.82Å; F244-E278 HydrophobicContact CG-CG 3.82Å; R246-E278 IonicContact NH2-OE2 2.87Å; N274-E278 WeakPolarHBondContact O-CB 3.34Å; N274-E278 PolarHBondContact O-N 2.83Å; F276-E278 VanDerWaalsContact C-N 3.29Å; F276-E278 PolarHBondContact O-N 3.06Å; E278-Y281 PolarHBondContact O-N 3.45Å; E278-I282 HydrophobicContact CG-CD1 4.24Å; E278-I282 WeakPolarHBondContact O-CD1 3.3Å; E278-I282 VanDerWaalsContact O-CG1 3.24Å; E278-I282 WeakPolarHBondContact O-CG1 3.37Å; E278-I282 PolarHBondContact O-N 3.05Å
279	K	91.4	Very high	93.2	Very high	65 Å²	65	34.2 Å²	34.2	28%	0.283	16%	0.159	S	C	.	.	H	α-helix	trans	-69.5	-39.6	-178.2	-51.6	-43.4	174.5	-165.9	0	112.5	L232 Y275 F276 I277 Y281 F283	L232-K279 VanDerWaalsContact CD2-NZ 3.3Å; Y275-K279 WeakPolarHBondContact O-CG 3.49Å; F276-K279 PolarHBondContact O-N 2.9Å; I277-K279 VanDerWaalsContact C-N 3.3Å; I277-K279 PolarHBondContact O-N 3.25Å; K279-Y281 VanDerWaalsContact C-N 3.34Å; K279-F283 WeakPolarHBondContact O-CB 3.15Å; K279-F283 PolarHBondContact O-N 2.91Å
280	V	93.9	Very high	93.2	Very high	11 Å²	11	38.1 Å²	38.1	7%	0.067	18%	0.18	C	C	.	.	H	α-helix	trans	-60.8	-45	175.9	172.4	0	0	0	0	110.7	F40 F276 I277 F283 L284	F40-V280 HydrophobicContact CB-CG1 3.96Å; F40-V280 HydrophobicContact CB-CG2 4.47Å; F40-V280 HydrophobicContact CD1-CB 4.26Å; F40-V280 HydrophobicContact CD1-CG1 3.92Å; F40-V280 HydrophobicContact CD1-CG2 3.49Å; F40-V280 VanDerWaalsContact CD1-CG2 3.49Å; F40-V280 HydrophobicContact CD2-CG1 3.97Å; F40-V280 HydrophobicContact CE1-CG1 4.45Å; F40-V280 HydrophobicContact CE1-CG2 3.93Å; F40-V280 HydrophobicContact CE2-CG1 4.45Å; F40-V280 HydrophobicContact CG-CG1 3.7Å; F40-V280 HydrophobicContact CG-CG2 4.11Å; F276-V280 WeakPolarHBondContact O-CG2 3.4Å; F276-V280 PolarHBondContact O-N 3.42Å; I277-V280 PolarHBondContact O-N 3Å; V280-F283 PolarHBondContact O-N 2.86Å; V280-L284 HydrophobicContact CG1-CD1 3.79Å; V280-L284 HydrophobicContact CG1-CG 4.27Å; V280-L284 WeakPolarHBondContact O-CB 3.41Å; V280-L284 VanDerWaalsContact O-CG 3.31Å; V280-L284 WeakPolarHBondContact O-CG 3.36Å; V280-L284 PolarHBondContact O-N 2.79Å
281	Y	93.6	Very high	93.4	Very high	1 Å²	1	34.7 Å²	34.7	0%	0.004	16%	0.159	C	C	.	.	H	α-helix	trans	-69.3	-39.3	-178.2	-89.8	-111.7	0	0	0	112.7	V107 M213 F216 I217 F244 I277 E278 K279 L284 W285	V107-Y281 HydrophobicContact CG2-CE2 3.62Å; M213-Y281 HydrophobicContact CB-CD1 4.3Å; M213-Y281 HydrophobicContact CB-CE1 4.13Å; M213-Y281 HydrophobicContact CE-CD1 3.59Å; M213-Y281 HydrophobicContact CE-CE1 4.24Å; M213-Y281 HydrophobicContact CE-CG 4.09Å; M213-Y281 VanDerWaalsContact CE-O 3.28Å; M213-Y281 WeakPolarHBondContact CE-O 3.47Å; M213-Y281 HydrophobicContact CG-CD1 4.33Å; M213-Y281 HydrophobicContact CG-CE1 4.07Å; F216-Y281 HydrophobicContact CD1-CE1 4.3Å; F216-Y281 AromaticContact CD1-CZ 3.98Å; F216-Y281 WeakPolarHBondContact CD1-OH 3.43Å; F216-Y281 WeakPolarHBondContact CE1-OH 3.45Å; I217-Y281 HydrophobicContact CD1-CD1 3.59Å; I217-Y281 HydrophobicContact CD1-CE1 4.07Å; I217-Y281 HydrophobicContact CD1-CG 4.47Å; I217-Y281 HydrophobicContact CG1-CD1 4.07Å; I217-Y281 HydrophobicContact CG1-CE1 4.09Å; F244-Y281 HydrophobicContact CZ-CG 4.3Å; I277-Y281 HydrophobicContact CG2-CD2 3.56Å; I277-Y281 HydrophobicContact CG2-CE2 3.68Å; I277-Y281 HydrophobicContact CG2-CG 4.45Å; I277-Y281 WeakPolarHBondContact O-CB 3.47Å; I277-Y281 WeakPolarHBondContact O-CD2 3.46Å; I277-Y281 PolarHBondContact O-N 3.43Å; E278-Y281 PolarHBondContact O-N 3.45Å; K279-Y281 VanDerWaalsContact C-N 3.34Å; Y281-L284 PolarHBondContact O-N 2.67Å; Y281-W285 VanDerWaalsContact O-CB 3.31Å; Y281-W285 WeakPolarHBondContact O-CB 3.34Å; Y281-W285 PolarHBondContact O-N 3.41Å
282	I	93.3	Very high	93.5	Very high	15 Å²	15	35.2 Å²	35.2	8%	0.077	16%	0.163	C	C	.	.	H	α-helix	trans	-60.1	-49.4	173.2	-66.3	163	0	0	0	109.9	V228 F229 L232 E278 L284 W285 F286	V228-I282 HydrophobicContact CB-CD1 4.42Å; V228-I282 HydrophobicContact CB-CG1 4.38Å; V228-I282 HydrophobicContact CG1-CD1 3.65Å; V228-I282 HydrophobicContact CG1-CG1 4.04Å; F229-I282 HydrophobicContact CB-CG2 4.37Å; F229-I282 HydrophobicContact CD2-CG2 4.24Å; L232-I282 HydrophobicContact CD1-CD1 3.45Å; L232-I282 VanDerWaalsContact CD1-CD1 3.45Å; E278-I282 HydrophobicContact CG-CD1 4.24Å; E278-I282 WeakPolarHBondContact O-CD1 3.3Å; E278-I282 VanDerWaalsContact O-CG1 3.24Å; E278-I282 WeakPolarHBondContact O-CG1 3.37Å; E278-I282 PolarHBondContact O-N 3.05Å; I282-L284 PolarHBondContact O-N 3.27Å; I282-W285 PolarHBondContact O-N 3.49Å; I282-F286 HydrophobicContact CG2-CD2 3.93Å; I282-F286 HydrophobicContact CG2-CE2 3.71Å; I282-F286 VanDerWaalsContact O-CD2 3.23Å; I282-F286 WeakPolarHBondContact O-CD2 2.75Å; I282-F286 PolarHBondContact O-N 2.81Å
283	F	95.6	Very high	93.8	Very high	93 Å²	93	36.6 Å²	36.6	41%	0.408	17%	0.174	S	C	.	.	H	α-helix	trans	-59.1	-49.2	178.5	175.9	-88.4	0	0	0	111.9	I36 F40 K279 V280 W285 F286 W287	I36-F283 HydrophobicContact CG2-CE1 3.79Å; F40-F283 AromaticContact CE2-CD1 3.41Å; F40-F283 HydrophobicContact CE2-CD1 3.41Å; F40-F283 VanDerWaalsContact CE2-CD1 3.41Å; F40-F283 AromaticContact CE2-CE1 3.65Å; F40-F283 HydrophobicContact CE2-CE1 3.65Å; F40-F283 HydrophobicContact CE2-CG 4.41Å; F40-F283 HydrophobicContact CZ-CB 4.45Å; F40-F283 AromaticContact CZ-CD1 3.35Å; F40-F283 HydrophobicContact CZ-CD1 3.35Å; F40-F283 AromaticContact CZ-CE1 3.71Å; F40-F283 HydrophobicContact CZ-CE1 3.71Å; F40-F283 AromaticContact CZ-CG 3.95Å; F40-F283 HydrophobicContact CZ-CG 3.95Å; K279-F283 WeakPolarHBondContact O-CB 3.15Å; K279-F283 PolarHBondContact O-N 2.91Å; V280-F283 PolarHBondContact O-N 2.86Å; F283-W285 VanDerWaalsContact C-N 3.3Å; F283-W285 PolarHBondContact O-N 3.07Å; F283-F286 PolarHBondContact O-N 3.3Å; F283-W287 HydrophobicContact CE1-CB 4.39Å; F283-W287 HydrophobicContact CZ-CE3 4.33Å; F283-W287 WeakPolarHBondContact O-CB 3.38Å; F283-W287 PolarHBondContact O-N 2.86Å
284	L	95.7	Very high	94.1	Very high	0 Å²	0	39.3 Å²	39.3	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-63.1	-36.2	179.7	-74.8	177.8	0	0	0	112	I36 I37 F40 L111 M213 V280 Y281 I282 W287 Y288	I36-L284 HydrophobicContact CG2-CD2 4.21Å; I37-L284 HydrophobicContact CG1-CD2 4.15Å; F40-L284 HydrophobicContact CD2-CD1 4.47Å; F40-L284 HydrophobicContact CD2-CD2 4.07Å; F40-L284 HydrophobicContact CD2-CG 4.27Å; F40-L284 HydrophobicContact CE2-CD2 3.94Å; F40-L284 HydrophobicContact CE2-CG 4.17Å; L111-L284 HydrophobicContact CD2-CD1 3.61Å; M213-L284 HydrophobicContact CE-CB 3.83Å; M213-L284 HydrophobicContact SD-CB 4.25Å; V280-L284 HydrophobicContact CG1-CD1 3.79Å; V280-L284 HydrophobicContact CG1-CG 4.27Å; V280-L284 WeakPolarHBondContact O-CB 3.41Å; V280-L284 VanDerWaalsContact O-CG 3.31Å; V280-L284 WeakPolarHBondContact O-CG 3.36Å; V280-L284 PolarHBondContact O-N 2.79Å; Y281-L284 PolarHBondContact O-N 2.67Å; I282-L284 PolarHBondContact O-N 3.27Å; L284-W287 WeakPolarHBondContact O-CB 3.25Å; L284-W287 PolarHBondContact O-N 3.36Å; L284-Y288 HydrophobicContact CB-CD2 4.36Å; L284-Y288 HydrophobicContact CB-CE2 4.17Å; L284-Y288 HydrophobicContact CD2-CE2 4.5Å; L284-Y288 WeakPolarHBondContact O-CD2 3.41Å; L284-Y288 PolarHBondContact O-N 2.95Å
285	W	95.5	Very high	94.3	Very high	13 Å²	13	39.4 Å²	39.4	5%	0.049	19%	0.188	C	C	.	.	H	α-helix	trans	-60.9	-50.7	176.1	-175.9	91	0	0	0	111.6	M213 T222 L223 F224 L226 Y281 I282 F283 W287 Y288 I289	M213-W285 HydrophobicContact CE-CB 4.24Å; T222-W285 PolarHBondContact O-NE1 2.96Å; T222-W285 VanDerWaalsContact O-NE1 3.09Å; L223-W285 HydrophobicContact CD2-CH2 4.43Å; L223-W285 HydrophobicContact CD2-CZ2 3.85Å; F224-W285 AromaticContact CE1-CD1 3.57Å; F224-W285 HydrophobicContact CZ-CB 4.41Å; F224-W285 AromaticContact CZ-CD1 3.68Å; F224-W285 HydrophobicContact CZ-CG 4.35Å; L226-W285 HydrophobicContact CB-CH2 3.8Å; L226-W285 HydrophobicContact CB-CZ2 4.41Å; L226-W285 HydrophobicContact CB-CZ3 4.13Å; Y281-W285 VanDerWaalsContact O-CB 3.31Å; Y281-W285 WeakPolarHBondContact O-CB 3.34Å; Y281-W285 PolarHBondContact O-N 3.41Å; I282-W285 PolarHBondContact O-N 3.49Å; F283-W285 VanDerWaalsContact C-N 3.3Å; F283-W285 PolarHBondContact O-N 3.07Å; W285-W287 VanDerWaalsContact C-N 3.3Å; W285-W287 PolarHBondContact O-N 2.89Å; W285-Y288 PolarHBondContact O-N 2.88Å; W285-I289 HydrophobicContact CD2-CG1 4.32Å; W285-I289 HydrophobicContact CE3-CG1 4.43Å; W285-I289 HydrophobicContact CH2-CG1 4.26Å; W285-I289 HydrophobicContact CZ2-CD1 4.38Å; W285-I289 HydrophobicContact CZ2-CG1 4.15Å; W285-I289 HydrophobicContact CZ3-CG1 4.41Å; W285-I289 WeakPolarHBondContact O-CG1 3.26Å; W285-I289 PolarHBondContact O-N 3.01Å; W285-I289 VanDerWaalsContact O-N 3.1Å
286	F	96.1	Very high	94.6	Very high	81 Å²	81	38.5 Å²	38.5	36%	0.355	19%	0.19	S	C	.	.	H	α-helix	trans	-61.7	-40	175.2	-76.1	-70.4	0	0	0	111.9	F229 I282 F283 I289 L290	F229-F286 HydrophobicContact CB-CE2 4.11Å; F229-F286 HydrophobicContact CB-CZ 4.18Å; F229-F286 HydrophobicContact CD1-CE2 4.49Å; F229-F286 HydrophobicContact CD1-CZ 4.07Å; F229-F286 HydrophobicContact CD2-CE2 4.18Å; F229-F286 HydrophobicContact CG-CE2 4.01Å; F229-F286 HydrophobicContact CG-CZ 4.01Å; I282-F286 HydrophobicContact CG2-CD2 3.93Å; I282-F286 HydrophobicContact CG2-CE2 3.71Å; I282-F286 VanDerWaalsContact O-CD2 3.23Å; I282-F286 WeakPolarHBondContact O-CD2 2.75Å; I282-F286 PolarHBondContact O-N 2.81Å; F283-F286 PolarHBondContact O-N 3.3Å; F286-I289 PolarHBondContact O-N 3Å; F286-L290 WeakPolarHBondContact O-CB 3.2Å; F286-L290 PolarHBondContact O-N 3.46Å
287	W	96.3	Very high	94.9	Very high	48 Å²	48	38.9 Å²	38.9	18%	0.182	20%	0.195	C	C	.	.	H	α-helix	trans	-60.5	-46.7	177.2	-176.9	-97.2	0	0	0	112.2	F32 T33 I36 F283 L284 W285 I289 L290 M291	F32-W287 HydrophobicContact CB-CZ2 4.43Å; T33-W287 PolarHBondContact OG1-NE1 2.95Å; I36-W287 HydrophobicContact CD1-CD2 4.01Å; I36-W287 HydrophobicContact CD1-CE3 4.19Å; I36-W287 HydrophobicContact CD1-CH2 3.64Å; I36-W287 HydrophobicContact CD1-CZ2 3.43Å; I36-W287 VanDerWaalsContact CD1-CZ2 3.43Å; I36-W287 HydrophobicContact CD1-CZ3 4.01Å; F283-W287 HydrophobicContact CE1-CB 4.39Å; F283-W287 HydrophobicContact CZ-CE3 4.33Å; F283-W287 WeakPolarHBondContact O-CB 3.38Å; F283-W287 PolarHBondContact O-N 2.86Å; L284-W287 WeakPolarHBondContact O-CB 3.25Å; L284-W287 PolarHBondContact O-N 3.36Å; W285-W287 VanDerWaalsContact C-N 3.3Å; W285-W287 PolarHBondContact O-N 2.89Å; W287-I289 PolarHBondContact O-N 3.03Å; W287-L290 WeakPolarHBondContact O-CB 3.37Å; W287-L290 PolarHBondContact O-N 3.27Å; W287-M291 HydrophobicContact CD2-CE 4.45Å; W287-M291 HydrophobicContact CH2-CE 4.1Å; W287-M291 HydrophobicContact CZ2-CE 3.86Å; W287-M291 HydrophobicContact CZ2-CG 4.42Å; W287-M291 HydrophobicContact CZ2-SD 4.02Å; W287-M291 HydrophobicContact CZ3-CE 4.48Å; W287-M291 WeakPolarHBondContact O-CG 3.11Å; W287-M291 PolarHBondContact O-N 2.93Å
288	Y	95.9	Very high	95	Very high	0 Å²	0	39.4 Å²	39.4	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-68.5	-34.2	179.3	-74	-58.3	0	0	0	113.1	T33 I37 Q209 M213 L284 W285 M291 A292	T33-Y288 HydrophobicContact CG2-CE1 3.65Å; I37-Y288 VanDerWaalsContact CD1-OH 3.29Å; I37-Y288 WeakPolarHBondContact CD1-OH 3.49Å; Q209-Y288 HydrophobicContact CB-CD1 3.92Å; Q209-Y288 HydrophobicContact CB-CD2 4.07Å; Q209-Y288 HydrophobicContact CB-CE1 3.67Å; Q209-Y288 HydrophobicContact CB-CE2 3.82Å; Q209-Y288 HydrophobicContact CB-CG 4.12Å; Q209-Y288 HydrophobicContact CG-CD1 4.19Å; Q209-Y288 HydrophobicContact CG-CE1 3.57Å; Q209-Y288 HydrophobicContact CG-CE2 4.42Å; M213-Y288 HydrophobicContact SD-CD2 3.67Å; M213-Y288 HydrophobicContact SD-CE2 3.66Å; L284-Y288 HydrophobicContact CB-CD2 4.36Å; L284-Y288 HydrophobicContact CB-CE2 4.17Å; L284-Y288 HydrophobicContact CD2-CE2 4.5Å; L284-Y288 WeakPolarHBondContact O-CD2 3.41Å; L284-Y288 PolarHBondContact O-N 2.95Å; W285-Y288 PolarHBondContact O-N 2.88Å; Y288-M291 PolarHBondContact O-N 2.86Å; Y288-A292 VanDerWaalsContact O-CB 3.22Å; Y288-A292 WeakPolarHBondContact O-CB 3.39Å; Y288-A292 PolarHBondContact O-N 3.06Å
289	I	95.5	Very high	95.1	Very high	72 Å²	72	39.5 Å²	39.5	37%	0.369	20%	0.199	S	C	.	.	H	α-helix	trans	-63.4	-43.9	171.7	-66.8	-68.9	0	0	0	110.6	I210 W285 F286 W287 A292 S293	I210-I289 HydrophobicContact CD1-CD1 3.6Å; I210-I289 HydrophobicContact CD1-CG1 4.17Å; W285-I289 HydrophobicContact CD2-CG1 4.32Å; W285-I289 HydrophobicContact CE3-CG1 4.43Å; W285-I289 HydrophobicContact CH2-CG1 4.26Å; W285-I289 HydrophobicContact CZ2-CD1 4.38Å; W285-I289 HydrophobicContact CZ2-CG1 4.15Å; W285-I289 HydrophobicContact CZ3-CG1 4.41Å; W285-I289 WeakPolarHBondContact O-CG1 3.26Å; W285-I289 PolarHBondContact O-N 3.01Å; W285-I289 VanDerWaalsContact O-N 3.1Å; F286-I289 PolarHBondContact O-N 3Å; W287-I289 PolarHBondContact O-N 3.03Å; I289-A292 PolarHBondContact O-N 3.46Å; I289-S293 PolarHBondContact O-N 3.1Å; I289-S293 PolarHBondContact O-OG 3.31Å
290	L	95.8	Very high	95.3	Very high	82 Å²	82	42.5 Å²	42.5	43%	0.429	21%	0.213	S	C	.	.	H	α-helix	trans	-61.4	-47.1	174	-179.4	65.2	0	0	0	111.3	F286 W287 A292 S293 L294	F286-L290 WeakPolarHBondContact O-CB 3.2Å; F286-L290 PolarHBondContact O-N 3.46Å; W287-L290 WeakPolarHBondContact O-CB 3.37Å; W287-L290 PolarHBondContact O-N 3.27Å; L290-A292 PolarHBondContact O-N 2.92Å; L290-S293 PolarHBondContact O-N 3.28Å; L290-S293 PolarHBondContact O-OG 3.17Å; L290-L294 HydrophobicContact CD1-CD1 4.13Å; L290-L294 HydrophobicContact CD1-CG 4.22Å; L290-L294 HydrophobicContact CG-CD1 4.04Å; L290-L294 HydrophobicContact CG-CG 4.48Å; L290-L294 WeakPolarHBondContact O-CB 3.36Å; L290-L294 WeakPolarHBondContact O-CG 3.26Å; L290-L294 PolarHBondContact O-N 3.18Å
291	M	95.9	Very high	95.3	Very high	2 Å²	2	45 Å²	45	1%	0.01	23%	0.225	C	C	.	.	H	α-helix	trans	-64.1	-40.1	178.2	-69.1	-54.4	101.2	0	0	112.3	L28 W287 Y288 L294 T295	L28-M291 HydrophobicContact CB-SD 3.78Å; W287-M291 HydrophobicContact CD2-CE 4.45Å; W287-M291 HydrophobicContact CH2-CE 4.1Å; W287-M291 HydrophobicContact CZ2-CE 3.86Å; W287-M291 HydrophobicContact CZ2-CG 4.42Å; W287-M291 HydrophobicContact CZ2-SD 4.02Å; W287-M291 HydrophobicContact CZ3-CE 4.48Å; W287-M291 WeakPolarHBondContact O-CG 3.11Å; W287-M291 PolarHBondContact O-N 2.93Å; Y288-M291 PolarHBondContact O-N 2.86Å; M291-L294 HydrophobicContact CE-CD1 3.8Å; M291-T295 WeakPolarHBondContact O-CB 3.07Å; M291-T295 VanDerWaalsContact O-CG2 3.25Å; M291-T295 WeakPolarHBondContact O-CG2 3.47Å; M291-T295 PolarHBondContact O-N 2.92Å; M291-T295 PolarHBondContact O-OG1 2.91Å
292	A	95.6	Very high	95.3	Very high	11 Å²	11	45.2 Å²	45.2	9%	0.091	23%	0.226	C	C	.	.	H	α-helix	trans	-61.3	-47.7	174.9	0	0	0	0	0	111.4	N206 Y288 I289 L290 T295 I296	N206-A292 HydrophobicContact CB-CB 4.04Å; Y288-A292 VanDerWaalsContact O-CB 3.22Å; Y288-A292 WeakPolarHBondContact O-CB 3.39Å; Y288-A292 PolarHBondContact O-N 3.06Å; I289-A292 PolarHBondContact O-N 3.46Å; L290-A292 PolarHBondContact O-N 2.92Å; A292-T295 WeakPolarHBondContact CA-OG1 3.47Å; A292-T295 PolarHBondContact O-N 2.86Å; A292-T295 PolarHBondContact O-OG1 3.29Å; A292-I296 WeakPolarHBondContact O-CB 3.4Å; A292-I296 WeakPolarHBondContact O-CD1 3.28Å; A292-I296 WeakPolarHBondContact O-CG1 3.49Å; A292-I296 PolarHBondContact O-N 3.11Å
293	S	96.3	Very high	95.3	Very high	60 Å²	60	47.8 Å²	47.8	42%	0.42	24%	0.239	S	C	.	.	H	α-helix	trans	-64.2	-45.5	178.9	60.7	0	0	0	0	112.6	I289 L290 T295 I296 L297	I289-S293 PolarHBondContact O-N 3.1Å; I289-S293 PolarHBondContact O-OG 3.31Å; L290-S293 PolarHBondContact O-N 3.28Å; L290-S293 PolarHBondContact O-OG 3.17Å; S293-T295 PolarHBondContact O-N 3.23Å; S293-I296 PolarHBondContact O-N 3.4Å; S293-L297 WeakPolarHBondContact O-CB 3.48Å; S293-L297 PolarHBondContact O-N 3.36Å
294	L	96.1	Very high	95.2	Very high	61 Å²	61	45.4 Å²	45.4	32%	0.319	23%	0.232	S	C	.	.	H	α-helix	trans	-63.1	-40.2	176.7	-69	177	0	0	0	112.1	V25 L28 L290 M291 N298	V25-L294 HydrophobicContact CG1-CB 4.27Å; L28-L294 HydrophobicContact CD1-CD1 4.36Å; L290-L294 HydrophobicContact CD1-CD1 4.13Å; L290-L294 HydrophobicContact CD1-CG 4.22Å; L290-L294 HydrophobicContact CG-CD1 4.04Å; L290-L294 HydrophobicContact CG-CG 4.48Å; L290-L294 WeakPolarHBondContact O-CB 3.36Å; L290-L294 WeakPolarHBondContact O-CG 3.26Å; L290-L294 PolarHBondContact O-N 3.18Å; M291-L294 HydrophobicContact CE-CD1 3.8Å; L294-N298 WeakPolarHBondContact O-CB 3.48Å; L294-N298 PolarHBondContact O-N 2.91Å
295	T	94.8	Very high	94.9	Very high	2 Å²	2	49.8 Å²	49.8	1%	0.012	25%	0.251	C	S	.	.	H	α-helix	trans	-68.7	-41.8	177.6	47.1	0	0	0	0	112.8	V25 N29 N206 M291 A292 S293 T299	V25-T295 HydrophobicContact CG1-CG2 3.73Å; N29-T295 WeakPolarHBondContact ND2-CG2 3.31Å; N29-T295 WeakPolarHBondContact OD1-CG2 3.27Å; N206-T295 PolarHBondContact ND2-OG1 3.41Å; M291-T295 WeakPolarHBondContact O-CB 3.07Å; M291-T295 VanDerWaalsContact O-CG2 3.25Å; M291-T295 WeakPolarHBondContact O-CG2 3.47Å; M291-T295 PolarHBondContact O-N 2.92Å; M291-T295 PolarHBondContact O-OG1 2.91Å; A292-T295 WeakPolarHBondContact CA-OG1 3.47Å; A292-T295 PolarHBondContact O-N 2.86Å; A292-T295 PolarHBondContact O-OG1 3.29Å; S293-T295 PolarHBondContact O-N 3.23Å; T295-T299 WeakPolarHBondContact O-CB 3.39Å; T295-T299 PolarHBondContact O-N 3.48Å; T295-T299 PolarHBondContact O-OG1 2.93Å
296	I	96.6	Very high	94.7	Very high	87 Å²	87	49.2 Å²	49.2	45%	0.446	25%	0.249	S	C	.	.	H	α-helix	trans	-62.8	-50.3	176.2	-70.1	165.8	0	0	0	110	I203 A292 S293 N298 T299 F300	I203-I296 HydrophobicContact CD1-CG1 4.01Å; I203-I296 HydrophobicContact CG1-CG1 4.06Å; I203-I296 HydrophobicContact CG2-CD1 4.3Å; I203-I296 HydrophobicContact CG2-CG1 3.94Å; A292-I296 WeakPolarHBondContact O-CB 3.4Å; A292-I296 WeakPolarHBondContact O-CD1 3.28Å; A292-I296 WeakPolarHBondContact O-CG1 3.49Å; A292-I296 PolarHBondContact O-N 3.11Å; S293-I296 PolarHBondContact O-N 3.4Å; I296-N298 PolarHBondContact O-N 3.03Å; I296-T299 PolarHBondContact O-N 3.27Å; I296-F300 PolarHBondContact O-N 3.32Å
297	L	96.3	Very high	94.3	Very high	103 Å²	103	47.7 Å²	47.7	54%	0.539	25%	0.248	S	C	.	.	H	α-helix	trans	-60.4	-46.9	179.4	-179.8	60.8	0	0	0	111.4	S293 T299 F300 I301	S293-L297 WeakPolarHBondContact O-CB 3.48Å; S293-L297 PolarHBondContact O-N 3.36Å; L297-T299 VanDerWaalsContact C-N 3.3Å; L297-T299 PolarHBondContact O-N 3.4Å; L297-F300 PolarHBondContact O-N 3.32Å; L297-I301 HydrophobicContact CD1-CD1 4.49Å; L297-I301 HydrophobicContact CG-CD1 4.23Å; L297-I301 WeakPolarHBondContact O-CG1 3.44Å; L297-I301 PolarHBondContact O-N 3.03Å
298	N	93.5	Very high	94	Very high	12 Å²	12	49.3 Å²	49.3	6%	0.064	26%	0.26	C	S	.	.	H	α-helix	trans	-62.5	-38.9	177.3	-170.9	38.4	0	0	0	111.6	V25 R199 L294 I296 I301 W302	V25-N298 HydrophobicContact CB-CB 4.34Å; V25-N298 WeakPolarHBondContact CB-ND2 3.23Å; V25-N298 HydrophobicContact CG1-CB 4.3Å; V25-N298 HydrophobicContact CG2-CB 4.03Å; R199-N298 VanDerWaalsContact NH1-C 3.33Å; R199-N298 PolarHBondContact NH1-ND2 3.44Å; R199-N298 PolarHBondContact NH2-ND2 3.3Å; L294-N298 WeakPolarHBondContact O-CB 3.48Å; L294-N298 PolarHBondContact O-N 2.91Å; I296-N298 PolarHBondContact O-N 3.03Å; N298-I301 PolarHBondContact O-N 3.46Å; N298-W302 VanDerWaalsContact O-CD1 3.28Å; N298-W302 PolarHBondContact O-N 2.7Å
299	T	94.3	Very high	93.6	Very high	10 Å²	10	52.8 Å²	52.8	6%	0.061	28%	0.282	C	S	.	.	H	α-helix	trans	-66.3	-41.1	177.4	-61.1	0	0	0	0	111.3	R199 I203 T295 I296 L297 I301 W302 I303	R199-T299 HydrophobicContact CB-CG2 4.04Å; R199-T299 VanDerWaalsContact NH1-N 3.12Å; R199-T299 PolarHBondContact NH1-OG1 2.71Å; I203-T299 HydrophobicContact CD1-CG2 4.15Å; T295-T299 WeakPolarHBondContact O-CB 3.39Å; T295-T299 PolarHBondContact O-N 3.48Å; T295-T299 PolarHBondContact O-OG1 2.93Å; I296-T299 PolarHBondContact O-N 3.27Å; L297-T299 VanDerWaalsContact C-N 3.3Å; L297-T299 PolarHBondContact O-N 3.4Å; T299-I301 VanDerWaalsContact C-N 3.34Å; T299-I301 PolarHBondContact O-N 3.23Å; T299-W302 PolarHBondContact O-N 3.23Å; T299-I303 HydrophobicContact CG2-CD1 3.99Å; T299-I303 HydrophobicContact CG2-CG1 4.41Å; T299-I303 VanDerWaalsContact O-CG1 3.3Å; T299-I303 WeakPolarHBondContact O-CG1 3.4Å; T299-I303 PolarHBondContact O-N 3.08Å
300	F	95.8	Very high	93.3	Very high	129 Å²	129	57.4 Å²	57.4	57%	0.566	30%	0.296	S	S	*	.	H	α-helix	trans	-61.6	-41.6	174.1	-173.1	-100.7	0	0	0	112.3	I296 L297 W302 I303 T304	I296-F300 PolarHBondContact O-N 3.32Å; L297-F300 PolarHBondContact O-N 3.32Å; F300-W302 VanDerWaalsContact C-N 3.32Å; F300-W302 PolarHBondContact O-N 2.97Å; F300-I303 PolarHBondContact O-N 2.62Å; F300-T304 HydrophobicContact CD1-CG2 4.19Å; F300-T304 HydrophobicContact CE1-CG2 3.8Å; F300-T304 HydrophobicContact CE2-CG2 4.41Å; F300-T304 HydrophobicContact CZ-CG2 3.93Å; F300-T304 WeakPolarHBondContact O-CG2 3.47Å; F300-T304 PolarHBondContact O-N 3.04Å; F300-T304 PolarHBondContact O-OG1 3.24Å; F300-T304 VanDerWaalsContact O-OG1 3.13Å
301	I	93.1	Very high	93.1	Very high	63 Å²	63	60.2 Å²	60.2	32%	0.323	30%	0.301	S	S	.	.	H	α-helix	trans	-60.2	-42.2	174.5	-67.9	165.6	0	0	0	111	L297 N298 T299 T304 K305	L297-I301 HydrophobicContact CD1-CD1 4.49Å; L297-I301 HydrophobicContact CG-CD1 4.23Å; L297-I301 WeakPolarHBondContact O-CG1 3.44Å; L297-I301 PolarHBondContact O-N 3.03Å; N298-I301 PolarHBondContact O-N 3.46Å; T299-I301 VanDerWaalsContact C-N 3.34Å; T299-I301 PolarHBondContact O-N 3.23Å; I301-T304 PolarHBondContact O-OG1 3.06Å; I301-K305 HydrophobicContact CG2-CD 4.12Å; I301-K305 WeakPolarHBondContact O-CB 3.49Å; I301-K305 VanDerWaalsContact O-CG 3.28Å; I301-K305 WeakPolarHBondContact O-CG 3.39Å; I301-K305 PolarHBondContact O-N 2.64Å; I301-K305 VanDerWaalsContact O-N 3.09Å
302	W	92.8	Very high	92.9	Very high	5 Å²	5	60.9 Å²	60.9	2%	0.019	30%	0.304	C	S	.	.	H	α-helix	trans	-68	-42.9	176.7	-85.5	101.3	0	0	0	112.9	V22 D23 F195 R199 N298 T299 F300 T304 K305 L306 F348 Q351 A352 K355	V22-W302 HydrophobicContact CG1-CH2 4.16Å; V22-W302 HydrophobicContact CG1-CZ2 3.89Å; D23-W302 VanDerWaalsContact CG-NE1 3.3Å; D23-W302 PolarHBondContact OD1-NE1 3.28Å; D23-W302 VanDerWaalsContact OD1-NE1 3.11Å; D23-W302 VanDerWaalsContact OD2-CE2 3.32Å; D23-W302 PolarHBondContact OD2-NE1 3.44Å; F195-W302 HydrophobicContact CE1-CB 4.34Å; F195-W302 AromaticContact CE1-CD2 3.78Å; F195-W302 HydrophobicContact CE1-CD2 3.78Å; F195-W302 HydrophobicContact CE1-CE3 4Å; F195-W302 AromaticContact CE1-CG 3.97Å; F195-W302 HydrophobicContact CE1-CG 3.97Å; F195-W302 HydrophobicContact CZ-CD2 4.13Å; F195-W302 HydrophobicContact CZ-CG 4.4Å; F195-W302 HydrophobicContact CZ-CZ2 4.33Å; R199-W302 VanDerWaalsContact NH2-NE1 3.13Å; N298-W302 VanDerWaalsContact O-CD1 3.28Å; N298-W302 PolarHBondContact O-N 2.7Å; T299-W302 PolarHBondContact O-N 3.23Å; F300-W302 VanDerWaalsContact C-N 3.32Å; F300-W302 PolarHBondContact O-N 2.97Å; W302-T304 VanDerWaalsContact C-N 3.33Å; W302-T304 PolarHBondContact O-N 3.49Å; W302-K305 PolarHBondContact O-N 3.03Å; W302-L306 HydrophobicContact CB-CD1 4.44Å; W302-L306 HydrophobicContact CE3-CD1 3.73Å; W302-L306 HydrophobicContact CE3-CD2 4.4Å; W302-L306 HydrophobicContact CE3-CG 4.03Å; W302-L306 HydrophobicContact CZ3-CD1 4.44Å; W302-L306 HydrophobicContact CZ3-CD2 4.49Å; W302-L306 WeakPolarHBondContact O-CB 3.24Å; W302-L306 VanDerWaalsContact O-CG 3.24Å; W302-L306 WeakPolarHBondContact O-CG 3.46Å; W302-L306 PolarHBondContact O-N 3.2Å; W302-F348 HydrophobicContact CE3-CD2 4.37Å; W302-F348 HydrophobicContact CH2-CD2 4.36Å; W302-F348 HydrophobicContact CH2-CE2 4.3Å; W302-F348 AromaticContact CZ3-CD2 3.78Å; W302-F348 HydrophobicContact CZ3-CD2 3.78Å; W302-F348 HydrophobicContact CZ3-CE2 4.09Å; W302-Q351 HydrophobicContact CH2-CB 4.01Å; W302-Q351 HydrophobicContact CZ3-CB 3.85Å; W302-A352 HydrophobicContact CH2-CB 4.38Å; W302-K355 HydrophobicContact CZ2-CD 4.32Å
303	I	93.2	Very high	92.7	Very high	69 Å²	69	61.5 Å²	61.5	35%	0.354	31%	0.306	S	S	.	.	H	α-helix	trans	-58	-47	175.8	-69.4	172.7	0	0	0	110.2	L196 T299 F300 K305 L306 C307	L196-I303 HydrophobicContact CD2-CG1 3.86Å; T299-I303 HydrophobicContact CG2-CD1 3.99Å; T299-I303 HydrophobicContact CG2-CG1 4.41Å; T299-I303 VanDerWaalsContact O-CG1 3.3Å; T299-I303 WeakPolarHBondContact O-CG1 3.4Å; T299-I303 PolarHBondContact O-N 3.08Å; F300-I303 PolarHBondContact O-N 2.62Å; I303-K305 VanDerWaalsContact C-N 3.34Å; I303-K305 PolarHBondContact O-N 3.45Å; I303-L306 PolarHBondContact O-N 3.01Å; I303-C307 HydrophobicContact CG2-CB 4.41Å; I303-C307 WeakPolarHBondContact O-CB 3.3Å; I303-C307 PolarHBondContact O-N 3.35Å; I303-C307 PolarHBondContact O-SG 3.3Å
304	T	93.4	Very high	92.5	Very high	44 Å²	44	61.5 Å²	61.5	27%	0.27	30%	0.3	S	S	.	.	H	α-helix	trans	-65	-36.3	179.2	55.6	0	0	0	0	112.6	F300 I301 W302 L308	F300-T304 HydrophobicContact CD1-CG2 4.19Å; F300-T304 HydrophobicContact CE1-CG2 3.8Å; F300-T304 HydrophobicContact CE2-CG2 4.41Å; F300-T304 HydrophobicContact CZ-CG2 3.93Å; F300-T304 WeakPolarHBondContact O-CG2 3.47Å; F300-T304 PolarHBondContact O-N 3.04Å; F300-T304 PolarHBondContact O-OG1 3.24Å; F300-T304 VanDerWaalsContact O-OG1 3.13Å; I301-T304 PolarHBondContact O-OG1 3.06Å; W302-T304 VanDerWaalsContact C-N 3.33Å; W302-T304 PolarHBondContact O-N 3.49Å; T304-L308 WeakPolarHBondContact O-CB 3.22Å; T304-L308 WeakPolarHBondContact O-CG 3.38Å
305	K	91	Very high	92.3	Very high	91 Å²	91	60.2 Å²	60.2	40%	0.396	29%	0.292	S	S	.	.	H	α-helix	trans	-70.9	-32.6	176.2	-74.2	179.3	178.2	-173.8	0	113.9	I301 W302 I303 R312	I301-K305 HydrophobicContact CG2-CD 4.12Å; I301-K305 WeakPolarHBondContact O-CB 3.49Å; I301-K305 VanDerWaalsContact O-CG 3.28Å; I301-K305 WeakPolarHBondContact O-CG 3.39Å; I301-K305 PolarHBondContact O-N 2.64Å; I301-K305 VanDerWaalsContact O-N 3.09Å; W302-K305 PolarHBondContact O-N 3.03Å; I303-K305 VanDerWaalsContact C-N 3.34Å; I303-K305 PolarHBondContact O-N 3.45Å; K305-R312 WeakPolarHBondContact O-CG 3.47Å
306	L	90	Very high	92.1	Very high	1 Å²	1	60.1 Å²	60.1	1%	0.005	29%	0.291	C	S	.	.	H	α-helix	trans	-96.7	-36.6	-173.7	-66.5	169.4	0	0	0	113.7	T192 L196 W302 I303 R312 F348	T192-L306 HydrophobicContact CG2-CB 4.33Å; T192-L306 HydrophobicContact CG2-CD1 3.77Å; T192-L306 HydrophobicContact CG2-CD2 4.18Å; T192-L306 HydrophobicContact CG2-CG 4.32Å; L196-L306 HydrophobicContact CD2-CD1 4.39Å; W302-L306 HydrophobicContact CB-CD1 4.44Å; W302-L306 HydrophobicContact CE3-CD1 3.73Å; W302-L306 HydrophobicContact CE3-CD2 4.4Å; W302-L306 HydrophobicContact CE3-CG 4.03Å; W302-L306 HydrophobicContact CZ3-CD1 4.44Å; W302-L306 HydrophobicContact CZ3-CD2 4.49Å; W302-L306 WeakPolarHBondContact O-CB 3.24Å; W302-L306 VanDerWaalsContact O-CG 3.24Å; W302-L306 WeakPolarHBondContact O-CG 3.46Å; W302-L306 PolarHBondContact O-N 3.2Å; I303-L306 PolarHBondContact O-N 3.01Å; L306-R312 VanDerWaalsContact O-CD 3.31Å; L306-R312 WeakPolarHBondContact O-CD 3.44Å; L306-R312 PolarHBondContact O-NH1 2.94Å; L306-F348 HydrophobicContact CD1-CD2 4.31Å; L306-F348 HydrophobicContact CD2-CB 3.76Å; L306-F348 HydrophobicContact CD2-CD2 4.35Å
307	C	87.7	Confident	91.9	Very high	50 Å²	50	58.8 Å²	58.8	34%	0.338	28%	0.28	S	S	.	.	H	α-helix	trans	-85.2	-31.8	-175.5	-64.2	0	0	0	0	112.5	I303 P309	I303-C307 HydrophobicContact CG2-CB 4.41Å; I303-C307 WeakPolarHBondContact O-CB 3.3Å; I303-C307 PolarHBondContact O-N 3.35Å; I303-C307 PolarHBondContact O-SG 3.3Å; C307-P309 VanDerWaalsContact O-CD 3.27Å; C307-P309 WeakPolarHBondContact O-CD 3.36Å
308	L	90.3	Very high	91.6	Very high	82 Å²	82	59.2 Å²	59.2	43%	0.429	28%	0.28	S	S	.	.			trans	-80.9	111.4	-177.7	-61.7	178.2	0	0	0	111.1	T304 Y310 R311 R312	T304-L308 WeakPolarHBondContact O-CB 3.22Å; T304-L308 WeakPolarHBondContact O-CG 3.38Å; L308-Y310 PolarHBondContact O-N 2.87Å; L308-R311 HydrophobicContact CB-CB 4.13Å; L308-R311 HydrophobicContact CB-CG 3.97Å; L308-R311 HydrophobicContact CD1-CG 4.03Å; L308-R311 PolarHBondContact O-N 3.02Å; L308-R311 VanDerWaalsContact O-N 3.17Å; L308-R312 WeakPolarHBondContact O-CG 3.49Å; L308-R312 PolarHBondContact O-N 3.43Å
309	P	87.4	Confident	91.5	Very high	72 Å²	72	59.8 Å²	59.8	47%	0.468	28%	0.281	S	S	.	.	H	α-helix	trans	-62.4	-31.4	-177.2	25.8	-34.5	0	0	0	112.6	C307 R312 V313	C307-P309 VanDerWaalsContact O-CD 3.27Å; C307-P309 WeakPolarHBondContact O-CD 3.36Å; P309-R312 WeakPolarHBondContact O-CB 3.4Å; P309-R312 PolarHBondContact O-N 3.47Å; P309-V313 WeakPolarHBondContact O-CG2 3.46Å; P309-V313 PolarHBondContact O-N 2.94Å; P309-V313 VanDerWaalsContact O-N 3.09Å
310	Y	90.3	Very high	91.3	Very high	169 Å²	169	59.3 Å²	59.3	66%	0.663	28%	0.278	S	S	*	.	H	α-helix	trans	-62.1	-48.9	176	178.8	-99.8	0	0	0	112.1	L308 R312 V313 Q314	L308-Y310 PolarHBondContact O-N 2.87Å; Y310-R312 VanDerWaalsContact C-N 3.29Å; Y310-R312 PolarHBondContact O-N 3.4Å; Y310-V313 PolarHBondContact O-N 2.99Å; Y310-Q314 VanDerWaalsContact O-CB 3.32Å; Y310-Q314 WeakPolarHBondContact O-CB 3.3Å; Y310-Q314 PolarHBondContact O-N 2.87Å
311	R	91.4	Very high	91	Very high	142 Å²	142	58 Å²	58	54%	0.536	27%	0.272	S	S	.	.	H	α-helix	trans	-62.5	-38.3	179.3	-70.5	-69.6	-172	163.7	1	111.8	L308 Q314 F315	L308-R311 HydrophobicContact CB-CB 4.13Å; L308-R311 HydrophobicContact CB-CG 3.97Å; L308-R311 HydrophobicContact CD1-CG 4.03Å; L308-R311 PolarHBondContact O-N 3.02Å; L308-R311 VanDerWaalsContact O-N 3.17Å; R311-Q314 PolarHBondContact O-N 3.33Å; R311-F315 WeakPolarHBondContact O-CB 3.24Å; R311-F315 PolarHBondContact O-N 3.48Å
312	R	91.5	Very high	90.7	Very high	15 Å²	15	58.2 Å²	58.2	6%	0.057	28%	0.284	C	S	.	.	H	α-helix	trans	-59.4	-50.9	175.1	-73.5	-165.3	-46	-151.8	7.6	113	K305 L306 L308 P309 Y310 Q314 F315 I316 V338 N339 W344 I347	K305-R312 WeakPolarHBondContact O-CG 3.47Å; L306-R312 VanDerWaalsContact O-CD 3.31Å; L306-R312 WeakPolarHBondContact O-CD 3.44Å; L306-R312 PolarHBondContact O-NH1 2.94Å; L308-R312 WeakPolarHBondContact O-CG 3.49Å; L308-R312 PolarHBondContact O-N 3.43Å; P309-R312 WeakPolarHBondContact O-CB 3.4Å; P309-R312 PolarHBondContact O-N 3.47Å; Y310-R312 VanDerWaalsContact C-N 3.29Å; Y310-R312 PolarHBondContact O-N 3.4Å; R312-Q314 VanDerWaalsContact C-N 3.34Å; R312-F315 PolarHBondContact O-N 3.01Å; R312-I316 PolarHBondContact O-N 3.32Å; R312-V338 HydrophobicContact CB-CG1 4.33Å; R312-N339 PolarHBondContact NH2-OD1 3.27Å; R312-W344 VanDerWaalsContact NH1-CD1 3.34Å; R312-W344 VanDerWaalsContact NH1-NE1 3.14Å; R312-I347 HydrophobicContact CB-CD1 3.85Å; R312-I347 HydrophobicContact CG-CD1 3.97Å; R312-I347 HydrophobicContact CG-CG2 4.18Å
313	V	91.2	Very high	90.5	Very high	25 Å²	25	60.3 Å²	60.3	15%	0.152	30%	0.295	C	S	.	.	H	α-helix	trans	-66	-41.4	178.1	176.1	0	0	0	0	110.2	P309 Y310 F315 I316 R317 A335 V338	P309-V313 WeakPolarHBondContact O-CG2 3.46Å; P309-V313 PolarHBondContact O-N 2.94Å; P309-V313 VanDerWaalsContact O-N 3.09Å; Y310-V313 PolarHBondContact O-N 2.99Å; V313-F315 VanDerWaalsContact C-N 3.34Å; V313-F315 PolarHBondContact O-N 2.95Å; V313-I316 PolarHBondContact O-N 3.43Å; V313-R317 WeakPolarHBondContact O-CB 3.26Å; V313-R317 PolarHBondContact O-N 2.98Å; V313-A335 HydrophobicContact CG1-CB 4.34Å; V313-A335 HydrophobicContact CG2-CB 4.28Å; V313-V338 HydrophobicContact CG2-CB 4.18Å; V313-V338 HydrophobicContact CG2-CG1 4.03Å
314	Q	91.4	Very high	90	Very high	60 Å²	60	66.4 Å²	66.4	28%	0.28	32%	0.319	S	S	.	.	H	α-helix	trans	-59.7	-42.6	178	-172.4	179.4	13.4	0	0	112.4	Y310 R311 R312 R317 Q318	Y310-Q314 VanDerWaalsContact O-CB 3.32Å; Y310-Q314 WeakPolarHBondContact O-CB 3.3Å; Y310-Q314 PolarHBondContact O-N 2.87Å; R311-Q314 PolarHBondContact O-N 3.33Å; R312-Q314 VanDerWaalsContact C-N 3.34Å; Q314-R317 PolarHBondContact O-N 3.04Å; Q314-Q318 WeakPolarHBondContact O-CG 3.39Å; Q314-Q318 PolarHBondContact O-N 3.05Å
315	F	91.8	Very high	89.3	Confident	33 Å²	33	67.9 Å²	67.9	15%	0.145	32%	0.322	C	S	.	.	H	α-helix	trans	-57.4	-55.1	177.7	177.3	-104.4	0	0	0	111.5	R311 R312 V313 R317 Q318 Y319 L350 Q351 V362	R311-F315 WeakPolarHBondContact O-CB 3.24Å; R311-F315 PolarHBondContact O-N 3.48Å; R312-F315 PolarHBondContact O-N 3.01Å; V313-F315 VanDerWaalsContact C-N 3.34Å; V313-F315 PolarHBondContact O-N 2.95Å; F315-R317 VanDerWaalsContact C-N 3.32Å; F315-R317 PolarHBondContact O-N 3.4Å; F315-Q318 PolarHBondContact O-N 3.36Å; F315-Y319 HydrophobicContact CD1-CE2 4.3Å; F315-Y319 AromaticContact CD2-CE2 3.93Å; F315-Y319 HydrophobicContact CD2-CE2 3.93Å; F315-Y319 HydrophobicContact CE1-CD2 4.44Å; F315-Y319 AromaticContact CE1-CE2 3.87Å; F315-Y319 HydrophobicContact CE1-CE2 3.87Å; F315-Y319 AromaticContact CE2-CE2 3.48Å; F315-Y319 HydrophobicContact CE2-CE2 3.48Å; F315-Y319 VanDerWaalsContact CE2-CE2 3.48Å; F315-Y319 HydrophobicContact CG-CE2 4.33Å; F315-Y319 HydrophobicContact CZ-CD2 4.41Å; F315-Y319 AromaticContact CZ-CE2 3.44Å; F315-Y319 HydrophobicContact CZ-CE2 3.44Å; F315-Y319 VanDerWaalsContact CZ-CE2 3.44Å; F315-Y319 VanDerWaalsContact O-CD2 3.24Å; F315-Y319 WeakPolarHBondContact O-CD2 3.39Å; F315-L350 HydrophobicContact CE1-CB 4.2Å; F315-Q351 HydrophobicContact CD1-CG 4.15Å; F315-Q351 HydrophobicContact CE1-CG 3.75Å; F315-Q351 HydrophobicContact CE2-CG 4.12Å; F315-Q351 HydrophobicContact CZ-CG 3.72Å; F315-V362 HydrophobicContact CZ-CG1 4.48Å
316	I	92.2	Very high	88.5	Confident	0 Å²	0	64.7 Å²	64.7	0%	0	31%	0.31	C	S	.	.	H	α-helix	trans	-64.5	-38.2	179.1	-61.4	-59.8	0	0	0	111.7	R312 V313 Q318 Y319 L320 F337 V338 L342 L350 T366	R312-I316 PolarHBondContact O-N 3.32Å; V313-I316 PolarHBondContact O-N 3.43Å; I316-Q318 VanDerWaalsContact C-N 3.27Å; I316-Q318 PolarHBondContact O-N 3.41Å; I316-Y319 PolarHBondContact O-N 3.18Å; I316-L320 HydrophobicContact CG2-CD1 3.91Å; I316-L320 HydrophobicContact CG2-CG 4.23Å; I316-L320 PolarHBondContact O-N 3.45Å; I316-F337 HydrophobicContact CG2-CE1 4.36Å; I316-V338 HydrophobicContact CB-CG2 3.79Å; I316-V338 HydrophobicContact CG1-CG2 3.88Å; I316-V338 HydrophobicContact CG2-CG2 3.84Å; I316-L342 HydrophobicContact CD1-CD2 4.01Å; I316-L342 HydrophobicContact CG1-CD2 4.24Å; I316-L350 HydrophobicContact CD1-CD1 3.63Å; I316-T366 HydrophobicContact CD1-CG2 4.37Å; I316-T366 HydrophobicContact CG2-CG2 3.9Å
317	R	91.1	Very high	87.8	Confident	59 Å²	59	67.1 Å²	67.1	22%	0.223	33%	0.327	C	S	.	.	H	α-helix	trans	-59.9	-35.8	177.5	-180	172.3	174.4	164.6	-1.3	112.4	V313 Q314 F315 K321 L326 E331	V313-R317 WeakPolarHBondContact O-CB 3.26Å; V313-R317 PolarHBondContact O-N 2.98Å; Q314-R317 PolarHBondContact O-N 3.04Å; F315-R317 VanDerWaalsContact C-N 3.32Å; F315-R317 PolarHBondContact O-N 3.4Å; R317-K321 HydrophobicContact CG-CD 4.25Å; R317-K321 HydrophobicContact CG-CG 4.47Å; R317-K321 VanDerWaalsContact NE-CE 3.35Å; R317-K321 VanDerWaalsContact NH2-NZ 3.11Å; R317-K321 WeakPolarHBondContact O-CB 3.21Å; R317-K321 VanDerWaalsContact O-CG 3.3Å; R317-K321 WeakPolarHBondContact O-CG 2.99Å; R317-K321 PolarHBondContact O-N 3.28Å; R317-L326 HydrophobicContact CG-CD2 3.85Å; R317-E331 IonicContact CZ-OE1 2.98Å; R317-E331 VanDerWaalsContact CZ-OE1 3.25Å; R317-E331 IonicContact CZ-OE2 3.33Å; R317-E331 IonicContact NH1-OE1 3.86Å; R317-E331 PolarHBondContact NH1-OE1 3.02Å; R317-E331 IonicContact NH1-OE2 2.63Å; R317-E331 PolarHBondContact NH1-OE2 3.11Å; R317-E331 IonicContact NH2-OE1 2.71Å; R317-E331 PolarHBondContact NH2-OE1 3.29Å; R317-E331 IonicContact NH2-OE2 3.97Å; R317-E331 PolarHBondContact NH2-OE2 3.43Å
318	Q	90.7	Very high	86.9	Confident	112 Å²	112	72 Å²	72	52%	0.523	34%	0.344	S	S	.	.	H	α-helix	trans	-64	-44.9	176.9	-74.6	170.6	-12.1	0	0	111.6	Q314 F315 I316 K321 A322	Q314-Q318 WeakPolarHBondContact O-CG 3.39Å; Q314-Q318 PolarHBondContact O-N 3.05Å; F315-Q318 PolarHBondContact O-N 3.36Å; I316-Q318 VanDerWaalsContact C-N 3.27Å; I316-Q318 PolarHBondContact O-N 3.41Å; Q318-K321 PolarHBondContact O-N 3.16Å; Q318-A322 PolarHBondContact O-N 2.97Å
319	Y	91.2	Very high	85.7	Confident	25 Å²	25	74 Å²	74	10%	0.098	36%	0.361	C	S	.	.	H	α-helix	trans	-66.7	-42.7	177	-68.3	-81	0	0	0	112.7	F315 I316 K321 A322 L323 S354 D359 V362 L363	F315-Y319 HydrophobicContact CD1-CE2 4.3Å; F315-Y319 AromaticContact CD2-CE2 3.93Å; F315-Y319 HydrophobicContact CD2-CE2 3.93Å; F315-Y319 HydrophobicContact CE1-CD2 4.44Å; F315-Y319 AromaticContact CE1-CE2 3.87Å; F315-Y319 HydrophobicContact CE1-CE2 3.87Å; F315-Y319 AromaticContact CE2-CE2 3.48Å; F315-Y319 HydrophobicContact CE2-CE2 3.48Å; F315-Y319 VanDerWaalsContact CE2-CE2 3.48Å; F315-Y319 HydrophobicContact CG-CE2 4.33Å; F315-Y319 HydrophobicContact CZ-CD2 4.41Å; F315-Y319 AromaticContact CZ-CE2 3.44Å; F315-Y319 HydrophobicContact CZ-CE2 3.44Å; F315-Y319 VanDerWaalsContact CZ-CE2 3.44Å; F315-Y319 VanDerWaalsContact O-CD2 3.24Å; F315-Y319 WeakPolarHBondContact O-CD2 3.39Å; I316-Y319 PolarHBondContact O-N 3.18Å; Y319-K321 VanDerWaalsContact C-N 3.33Å; Y319-K321 PolarHBondContact O-N 3.49Å; Y319-A322 WeakPolarHBondContact O-CB 3.28Å; Y319-A322 PolarHBondContact O-N 3.39Å; Y319-L323 PolarHBondContact O-N 3.01Å; Y319-S354 PolarHBondContact OH-OG 3.3Å; Y319-D359 HydrophobicContact CE1-CB 4.07Å; Y319-D359 PolarHBondContact OH-OD1 2.97Å; Y319-V362 HydrophobicContact CD1-CG1 4.26Å; Y319-V362 HydrophobicContact CD2-CG1 4.27Å; Y319-V362 HydrophobicContact CE1-CB 4.12Å; Y319-V362 HydrophobicContact CE1-CG1 3.9Å; Y319-V362 HydrophobicContact CE2-CG1 3.94Å; Y319-V362 HydrophobicContact CG-CG1 4.43Å; Y319-L363 HydrophobicContact CD1-CB 3.96Å
320	L	89.6	Confident	85.2	Confident	0 Å²	0	72.3 Å²	72.3	0%	0	35%	0.346	C	S	.	.	H	α-helix	trans	-67.1	-34.2	179.1	-66.8	177	0	0	0	112.9	I316 L323 K324 Q325 L326 T366 W370	I316-L320 HydrophobicContact CG2-CD1 3.91Å; I316-L320 HydrophobicContact CG2-CG 4.23Å; I316-L320 PolarHBondContact O-N 3.45Å; L320-L323 PolarHBondContact O-N 3.35Å; L320-K324 PolarHBondContact O-N 2.98Å; L320-Q325 PolarHBondContact O-N 2.83Å; L320-L326 HydrophobicContact CB-CB 3.93Å; L320-L326 HydrophobicContact CB-CD2 4.39Å; L320-L326 HydrophobicContact CD1-CD1 4.46Å; L320-T366 HydrophobicContact CD2-CG2 3.87Å; L320-T366 HydrophobicContact CG-CG2 4.08Å; L320-W370 HydrophobicContact CD1-CD2 3.97Å; L320-W370 HydrophobicContact CD1-CE3 4.02Å; L320-W370 HydrophobicContact CD1-CG 4.22Å; L320-W370 HydrophobicContact CD2-CB 3.62Å; L320-W370 HydrophobicContact CD2-CD2 4.37Å; L320-W370 HydrophobicContact CD2-CG 3.75Å
321	K	89.1	Confident	84.7	Confident	101 Å²	101	67.2 Å²	67.2	44%	0.439	33%	0.328	S	S	.	.	H	α-helix	trans	-66.2	-41	171.4	-78.4	-176.3	173.1	-173.3	0	111.8	R317 Q318 Y319 L323 K324 L326	R317-K321 HydrophobicContact CG-CD 4.25Å; R317-K321 HydrophobicContact CG-CG 4.47Å; R317-K321 VanDerWaalsContact NE-CE 3.35Å; R317-K321 VanDerWaalsContact NH2-NZ 3.11Å; R317-K321 WeakPolarHBondContact O-CB 3.21Å; R317-K321 VanDerWaalsContact O-CG 3.3Å; R317-K321 WeakPolarHBondContact O-CG 2.99Å; R317-K321 PolarHBondContact O-N 3.28Å; Q318-K321 PolarHBondContact O-N 3.16Å; Y319-K321 VanDerWaalsContact C-N 3.33Å; Y319-K321 PolarHBondContact O-N 3.49Å; K321-L323 PolarHBondContact O-N 3.48Å; K321-K324 PolarHBondContact O-N 2.95Å; K321-L326 HydrophobicContact CG-CD2 4.31Å
322	A	88.4	Confident	84.3	Confident	68 Å²	68	65.3 Å²	65.3	56%	0.562	33%	0.332	S	S	*	.	H	α-helix	trans	-61.2	-35.3	175.7	0	0	0	0	0	111.9	Q318 Y319 K324 L363	Q318-A322 PolarHBondContact O-N 2.97Å; Y319-A322 WeakPolarHBondContact O-CB 3.28Å; Y319-A322 PolarHBondContact O-N 3.39Å; A322-K324 VanDerWaalsContact C-N 3.27Å; A322-K324 PolarHBondContact O-N 3.13Å; A322-L363 HydrophobicContact CB-CD1 4.02Å
323	L	87.7	Confident	84	Confident	49 Å²	49	66.2 Å²	66.2	26%	0.257	34%	0.338	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75.3	-6.5	173.8	-80.9	169.8	0	0	0	115	Y319 L320 K321 Q325 L363	Y319-L323 PolarHBondContact O-N 3.01Å; L320-L323 PolarHBondContact O-N 3.35Å; K321-L323 PolarHBondContact O-N 3.48Å; L323-Q325 HydrophobicContact CB-CB 4.26Å; L323-Q325 HydrophobicContact CB-CG 4.05Å; L323-Q325 PolarHBondContact O-N 3.5Å; L323-Q325 VanDerWaalsContact O-N 3.11Å; L323-L363 HydrophobicContact CD1-CD2 4.23Å; L323-L363 HydrophobicContact CD1-CG 4.22Å; L323-L363 WeakPolarHBondContact CD1-O 3.5Å; L323-L363 HydrophobicContact CD2-CD2 3.33Å; L323-L363 HydrophobicContact CD2-CG 4.07Å; L323-L363 HydrophobicContact CG-CD1 4.49Å; L323-L363 HydrophobicContact CG-CD2 3.69Å; L323-L363 HydrophobicContact CG-CG 3.83Å
324	K	83.2	Confident	83.8	Confident	196 Å²	196	65.1 Å²	65.1	85%	0.852	33%	0.331	S	S	*	.	T	Hydrogen-bonded Turn	trans	54.1	23.1	-171.2	-56.2	-179.2	-180	179.2	0	114	L320 K321 A322	L320-K324 PolarHBondContact O-N 2.98Å; K321-K324 PolarHBondContact O-N 2.95Å; A322-K324 VanDerWaalsContact C-N 3.27Å; A322-K324 PolarHBondContact O-N 3.13Å
325	Q	78.5	Confident	83.7	Confident	75 Å²	75	63.7 Å²	63.7	35%	0.35	33%	0.33	S	S	.	.			trans	-92.3	-7.2	-179.5	-76.7	-176.6	-12.6	0	0	113.5	L320 L323	L320-Q325 PolarHBondContact O-N 2.83Å; L323-Q325 HydrophobicContact CB-CB 4.26Å; L323-Q325 HydrophobicContact CB-CG 4.05Å; L323-Q325 PolarHBondContact O-N 3.5Å; L323-Q325 VanDerWaalsContact O-N 3.11Å
326	L	74.4	Confident	83.4	Confident	24 Å²	24	67.2 Å²	67.2	13%	0.126	34%	0.342	C	S	.	.			trans	-111.6	116.2	-177.1	-169.7	72.4	0	0	0	111.1	R317 L320 K321 E330 C334 W370	R317-L326 HydrophobicContact CG-CD2 3.85Å; L320-L326 HydrophobicContact CB-CB 3.93Å; L320-L326 HydrophobicContact CB-CD2 4.39Å; L320-L326 HydrophobicContact CD1-CD1 4.46Å; K321-L326 HydrophobicContact CG-CD2 4.31Å; L326-E330 HydrophobicContact CD1-CB 3.82Å; L326-C334 HydrophobicContact CD1-CB 4.11Å; L326-W370 HydrophobicContact CD1-CH2 4.39Å; L326-W370 HydrophobicContact CD1-CZ2 4.03Å
327	S	74.9	Confident	83.2	Confident	53 Å²	53	67.6 Å²	67.6	37%	0.371	34%	0.344	S	S	.	.			trans	-85.1	160.9	168.7	69.4	0	0	0	0	111.9	T329 E330	S327-T329 PolarHBondContact O-N 3.42Å; S327-T329 PolarHBondContact OG-OG1 3Å; S327-T329 VanDerWaalsContact OG-OG1 3.06Å; S327-E330 PolarHBondContact N-OE2 3.42Å; S327-E330 PolarHBondContact O-N 2.99Å; S327-E330 VanDerWaalsContact OG-CD 3.29Å; S327-E330 WeakPolarHBondContact OG-CG 3.48Å; S327-E330 PolarHBondContact OG-OE2 3.38Å
328	H	69	Low	83.2	Confident	152 Å²	152	64.8 Å²	64.8	70%	0.704	33%	0.333	S	S	*	.	G	3₁₀ helix	trans	-62	-27.3	178.7	-103.2	-71.6	0	0	0	113.5	E330 E331	H328-E330 VanDerWaalsContact C-N 3.28Å; H328-E330 PolarHBondContact O-N 3.11Å; H328-E331 IonicContact CE1-OE1 3.97Å; H328-E331 IonicContact ND1-OE1 3.97Å; H328-E331 PolarHBondContact ND1-OE1 2.87Å; H328-E331 VanDerWaalsContact ND1-OE1 3.08Å; H328-E331 WeakPolarHBondContact O-CG 3.46Å
329	T	64.7	Low	83	Confident	125 Å²	125	62.4 Å²	62.4	77%	0.767	32%	0.324	S	S	*	.	G	3₁₀ helix	trans	-75.1	-16.7	179.2	47.4	0	0	0	0	112.9	S327	S327-T329 PolarHBondContact O-N 3.42Å; S327-T329 PolarHBondContact OG-OG1 3Å; S327-T329 VanDerWaalsContact OG-OG1 3.06Å
330	E	77.7	Confident	82.6	Confident	36 Å²	36	63.7 Å²	63.7	17%	0.168	33%	0.332	C	S	.	.	G	3₁₀ helix	trans	-94	7.4	-175.1	-68.9	169.7	128.2	0	0	114.2	L326 S327 H328 T332 E333 C334 W370 Q374	L326-E330 HydrophobicContact CD1-CB 3.82Å; S327-E330 PolarHBondContact N-OE2 3.42Å; S327-E330 PolarHBondContact O-N 2.99Å; S327-E330 VanDerWaalsContact OG-CD 3.29Å; S327-E330 WeakPolarHBondContact OG-CG 3.48Å; S327-E330 PolarHBondContact OG-OE2 3.38Å; H328-E330 VanDerWaalsContact C-N 3.28Å; H328-E330 PolarHBondContact O-N 3.11Å; E330-T332 PolarHBondContact O-N 2.98Å; E330-E333 HydrophobicContact CB-CB 4.48Å; E330-E333 HydrophobicContact CB-CG 4.49Å; E330-E333 CarbonylContact O-C 3.53Å; E330-E333 WeakPolarHBondContact O-CA 3.32Å; E330-E333 VanDerWaalsContact O-CB 3.31Å; E330-E333 WeakPolarHBondContact O-CB 3.42Å; E330-E333 PolarHBondContact O-N 2.9Å; E330-C334 PolarHBondContact O-N 2.86Å; E330-W370 HydrophobicContact CB-CZ2 4.43Å; E330-Q374 PolarHBondContact OE1-NE2 2.72Å
331	E	78.3	Confident	82.4	Confident	62 Å²	62	64.7 Å²	64.7	29%	0.29	34%	0.337	S	S	.	.	H	α-helix	trans	-60.6	-45.3	-175.5	-70.2	-173.2	-170.9	0	0	113.3	R317 H328 E333 C334 A335	R317-E331 IonicContact CZ-OE1 2.98Å; R317-E331 VanDerWaalsContact CZ-OE1 3.25Å; R317-E331 IonicContact CZ-OE2 3.33Å; R317-E331 IonicContact NH1-OE1 3.86Å; R317-E331 PolarHBondContact NH1-OE1 3.02Å; R317-E331 IonicContact NH1-OE2 2.63Å; R317-E331 PolarHBondContact NH1-OE2 3.11Å; R317-E331 IonicContact NH2-OE1 2.71Å; R317-E331 PolarHBondContact NH2-OE1 3.29Å; R317-E331 IonicContact NH2-OE2 3.97Å; R317-E331 PolarHBondContact NH2-OE2 3.43Å; H328-E331 IonicContact CE1-OE1 3.97Å; H328-E331 IonicContact ND1-OE1 3.97Å; H328-E331 PolarHBondContact ND1-OE1 2.87Å; H328-E331 VanDerWaalsContact ND1-OE1 3.08Å; H328-E331 WeakPolarHBondContact O-CG 3.46Å; E331-E333 PolarHBondContact O-N 2.67Å; E331-C334 WeakPolarHBondContact O-CB 3.5Å; E331-C334 PolarHBondContact O-N 3.49Å; E331-A335 PolarHBondContact O-N 3.26Å
332	T	84	Confident	82.3	Confident	101 Å²	101	60.2 Å²	60.2	62%	0.62	32%	0.318	S	S	*	.	H	α-helix	trans	-65.6	-26.7	175.7	-47.2	0	0	0	0	111.4	E330 R336	E330-T332 PolarHBondContact O-N 2.98Å; T332-R336 WeakPolarHBondContact O-CG 3.41Å; T332-R336 PolarHBondContact O-N 3.48Å; T332-R336 PolarHBondContact O-NE 3.32Å
333	E	85.6	Confident	82.2	Confident	35 Å²	35	57 Å²	57	16%	0.164	29%	0.293	C	S	.	.	H	α-helix	trans	-76.1	-41.3	176.4	-47.3	-135.3	129.8	0	0	111.2	E330 E331 A335 R336 F337 W370 K377	E330-E333 HydrophobicContact CB-CB 4.48Å; E330-E333 HydrophobicContact CB-CG 4.49Å; E330-E333 CarbonylContact O-C 3.53Å; E330-E333 WeakPolarHBondContact O-CA 3.32Å; E330-E333 VanDerWaalsContact O-CB 3.31Å; E330-E333 WeakPolarHBondContact O-CB 3.42Å; E330-E333 PolarHBondContact O-N 2.9Å; E331-E333 PolarHBondContact O-N 2.67Å; E333-A335 VanDerWaalsContact C-N 3.35Å; E333-A335 PolarHBondContact O-N 3.4Å; E333-R336 WeakPolarHBondContact O-CB 3.48Å; E333-R336 PolarHBondContact O-N 3.17Å; E333-R336 VanDerWaalsContact O-N 3.17Å; E333-R336 IonicContact OE1-CZ 2.95Å; E333-R336 IonicContact OE1-NH2 2.95Å; E333-R336 PolarHBondContact OE1-NH2 3.04Å; E333-F337 WeakPolarHBondContact O-CB 3.39Å; E333-F337 PolarHBondContact O-N 3.23Å; E333-W370 HydrophobicContact CB-CH2 4.16Å; E333-K377 IonicContact OE1-NZ 3.42Å; E333-K377 PolarHBondContact OE1-NZ 2.96Å; E333-K377 IonicContact OE2-NZ 3.6Å; E333-K377 PolarHBondContact OE2-NZ 3.47Å
334	C	86.9	Confident	82.3	Confident	1 Å²	1	59.2 Å²	59.2	1%	0.007	30%	0.297	C	S	.	.	H	α-helix	trans	-58.7	-46.8	173.2	-174.3	0	0	0	0	110.8	L326 E330 E331 R336 F337 V338 W370	L326-C334 HydrophobicContact CD1-CB 4.11Å; E330-C334 PolarHBondContact O-N 2.86Å; E331-C334 WeakPolarHBondContact O-CB 3.5Å; E331-C334 PolarHBondContact O-N 3.49Å; C334-R336 VanDerWaalsContact C-N 3.28Å; C334-R336 PolarHBondContact O-N 3.26Å; C334-F337 WeakPolarHBondContact O-CB 3.02Å; C334-F337 PolarHBondContact O-N 2.97Å; C334-V338 VanDerWaalsContact O-CG2 3.28Å; C334-V338 WeakPolarHBondContact O-CG2 3.47Å; C334-V338 PolarHBondContact O-N 3.41Å; C334-W370 HydrophobicContact CB-CH2 4.41Å; C334-W370 HydrophobicContact CB-CZ3 4.47Å
335	A	88.2	Confident	82.6	Confident	31 Å²	31	50.1 Å²	50.1	26%	0.256	26%	0.258	S	S	.	.	H	α-helix	trans	-59.9	-37.6	176.2	0	0	0	0	0	112.8	V313 E331 E333 N339	V313-A335 HydrophobicContact CG1-CB 4.34Å; V313-A335 HydrophobicContact CG2-CB 4.28Å; E331-A335 PolarHBondContact O-N 3.26Å; E333-A335 VanDerWaalsContact C-N 3.35Å; E333-A335 PolarHBondContact O-N 3.4Å; A335-N339 WeakPolarHBondContact O-CB 3.31Å; A335-N339 PolarHBondContact O-N 3.18Å; A335-N339 PolarHBondContact O-ND2 3.06Å
336	R	86.6	Confident	83.2	Confident	106 Å²	106	46.6 Å²	46.6	40%	0.4	24%	0.241	S	C	.	.	H	α-helix	trans	-67.6	-45.1	173.8	-77.8	-177.6	-76.7	155.5	-3.2	111.7	T332 E333 C334 N340	T332-R336 WeakPolarHBondContact O-CG 3.41Å; T332-R336 PolarHBondContact O-N 3.48Å; T332-R336 PolarHBondContact O-NE 3.32Å; E333-R336 WeakPolarHBondContact O-CB 3.48Å; E333-R336 PolarHBondContact O-N 3.17Å; E333-R336 VanDerWaalsContact O-N 3.17Å; E333-R336 IonicContact OE1-CZ 2.95Å; E333-R336 IonicContact OE1-NH2 2.95Å; E333-R336 PolarHBondContact OE1-NH2 3.04Å; C334-R336 VanDerWaalsContact C-N 3.28Å; C334-R336 PolarHBondContact O-N 3.26Å; R336-N340 WeakPolarHBondContact O-CA 3.28Å; R336-N340 WeakPolarHBondContact O-CB 3.31Å; R336-N340 PolarHBondContact O-N 2.79Å
337	F	88.6	Confident	84	Confident	9 Å²	9	45.4 Å²	45.4	4%	0.039	24%	0.235	C	C	.	.	I	π-helix	trans	-57.7	-49.5	176.8	168	-107.2	0	0	0	111.7	I316 E333 C334 N341 L342 L369 W370 Y373	I316-F337 HydrophobicContact CG2-CE1 4.36Å; E333-F337 WeakPolarHBondContact O-CB 3.39Å; E333-F337 PolarHBondContact O-N 3.23Å; C334-F337 WeakPolarHBondContact O-CB 3.02Å; C334-F337 PolarHBondContact O-N 2.97Å; F337-N341 HydrophobicContact CD2-CB 4.22Å; F337-N341 WeakPolarHBondContact O-CB 3.42Å; F337-N341 PolarHBondContact O-N 2.95Å; F337-L342 PolarHBondContact O-N 3.44Å; F337-L342 VanDerWaalsContact O-N 3.11Å; F337-L369 HydrophobicContact CZ-CB 3.94Å; F337-W370 HydrophobicContact CB-CE3 4.19Å; F337-W370 HydrophobicContact CB-CZ3 3.68Å; F337-W370 AromaticContact CD1-CE3 3.77Å; F337-W370 HydrophobicContact CD1-CE3 3.77Å; F337-W370 HydrophobicContact CD1-CZ3 4.04Å; F337-W370 HydrophobicContact CD2-CE3 4.3Å; F337-W370 HydrophobicContact CE1-CE3 4.2Å; F337-W370 AromaticContact CG-CE3 3.83Å; F337-W370 HydrophobicContact CG-CE3 3.83Å; F337-W370 AromaticContact CG-CZ3 3.85Å; F337-W370 HydrophobicContact CG-CZ3 3.85Å; F337-Y373 HydrophobicContact CB-CD1 4.16Å; F337-Y373 HydrophobicContact CB-CE1 3.97Å; F337-Y373 AromaticContact CD2-CD1 3.77Å; F337-Y373 HydrophobicContact CD2-CD1 3.77Å; F337-Y373 AromaticContact CD2-CD2 3.99Å; F337-Y373 HydrophobicContact CD2-CD2 3.99Å; F337-Y373 HydrophobicContact CD2-CE1 4.34Å; F337-Y373 HydrophobicContact CD2-CE2 4.5Å; F337-Y373 AromaticContact CD2-CG 3.55Å; F337-Y373 HydrophobicContact CD2-CG 3.55Å; F337-Y373 HydrophobicContact CE2-CG 4.11Å; F337-Y373 HydrophobicContact CG-CD1 4.24Å; F337-Y373 HydrophobicContact CG-CG 4.45Å
338	V	89.7	Confident	84.8	Confident	0 Å²	0	43 Å²	43	0%	0	22%	0.218	C	C	.	.	I	π-helix	trans	-64.1	-51.4	-179.2	175.8	0	0	0	0	111.4	R312 V313 I316 C334 G343 I347	R312-V338 HydrophobicContact CB-CG1 4.33Å; V313-V338 HydrophobicContact CG2-CB 4.18Å; V313-V338 HydrophobicContact CG2-CG1 4.03Å; I316-V338 HydrophobicContact CB-CG2 3.79Å; I316-V338 HydrophobicContact CG1-CG2 3.88Å; I316-V338 HydrophobicContact CG2-CG2 3.84Å; C334-V338 VanDerWaalsContact O-CG2 3.28Å; C334-V338 WeakPolarHBondContact O-CG2 3.47Å; C334-V338 PolarHBondContact O-N 3.41Å; V338-G343 PolarHBondContact O-N 3.18Å; V338-I347 HydrophobicContact CG1-CD1 3.46Å; V338-I347 VanDerWaalsContact CG1-CD1 3.46Å; V338-I347 HydrophobicContact CG1-CG1 4.31Å
339	N	86.6	Confident	85.9	Confident	61 Å²	61	36 Å²	36	33%	0.326	19%	0.186	S	C	.	.	I	π-helix	trans	-77.4	-31.2	-175.1	-70.3	-51.1	0	0	0	113.6	R312 A335	R312-N339 PolarHBondContact NH2-OD1 3.27Å; A335-N339 WeakPolarHBondContact O-CB 3.31Å; A335-N339 PolarHBondContact O-N 3.18Å; A335-N339 PolarHBondContact O-ND2 3.06Å
340	N	83.6	Confident	87.2	Confident	52 Å²	52	30.3 Å²	30.3	28%	0.278	15%	0.151	S	C	.	.	I	π-helix	trans	-96.6	-45.3	-174	-64.1	-36.4	0	0	0	114.3	S168 R172 R336	S168-N340 PolarHBondContact OG-O 3.28Å; R172-N340 PolarHBondContact NH1-OD1 3.35Å; R172-N340 VanDerWaalsContact NH2-CA 3.32Å; R172-N340 VanDerWaalsContact NH2-CB 3.35Å; R172-N340 PolarHBondContact NH2-OD1 3.1Å; R336-N340 WeakPolarHBondContact O-CA 3.28Å; R336-N340 WeakPolarHBondContact O-CB 3.31Å; R336-N340 PolarHBondContact O-N 2.79Å
341	N	84.4	Confident	87.9	Confident	21 Å²	21	29.2 Å²	29.2	11%	0.112	15%	0.146	C	C	.	.	I	π-helix	trans	-89.9	-54.3	-176.4	-76.1	6.2	0	0	0	111.1	S165 K169 F337 Y373	S165-N341 VanDerWaalsContact CA-O 3.26Å; S165-N341 WeakPolarHBondContact CA-O 3.35Å; S165-N341 VanDerWaalsContact CB-O 3.28Å; S165-N341 WeakPolarHBondContact CB-O 3.19Å; K169-N341 WeakPolarHBondContact CE-OD1 3.5Å; F337-N341 HydrophobicContact CD2-CB 4.22Å; F337-N341 WeakPolarHBondContact O-CB 3.42Å; F337-N341 PolarHBondContact O-N 2.95Å; N341-Y373 WeakPolarHBondContact ND2-CD2 3.4Å; N341-Y373 WeakPolarHBondContact ND2-CE2 3.25Å
342	L	87.5	Confident	88.5	Confident	7 Å²	7	26.3 Å²	26.3	4%	0.037	13%	0.132	C	C	.	.	I	π-helix	trans	-74.2	-39.5	-174.2	-168.6	65.6	0	0	0	112	L161 I316 F337 G346 I347 L350	L161-L342 HydrophobicContact CD2-CD1 3.88Å; I316-L342 HydrophobicContact CD1-CD2 4.01Å; I316-L342 HydrophobicContact CG1-CD2 4.24Å; F337-L342 PolarHBondContact O-N 3.44Å; F337-L342 VanDerWaalsContact O-N 3.11Å; L342-G346 WeakPolarHBondContact O-CA 3.38Å; L342-G346 PolarHBondContact O-N 3.36Å; L342-I347 HydrophobicContact CD2-CD1 4.43Å; L342-I347 HydrophobicContact CD2-CG1 3.46Å; L342-I347 VanDerWaalsContact CD2-CG1 3.46Å; L342-I347 HydrophobicContact CG-CG1 3.95Å; L342-L350 HydrophobicContact CD1-CD1 4.31Å; L342-L350 HydrophobicContact CD2-CD1 3.78Å
343	G	87.1	Confident	88.7	Confident	2 Å²	2	21.5 Å²	21.5	2%	0.021	10%	0.103	C	C	.	.	H	α-helix	trans	63.9	-162.3	178.8	0	0	0	0	0	112.6	V338 I347	V338-G343 PolarHBondContact O-N 3.18Å; G343-I347 WeakPolarHBondContact O-CD1 3.35Å; G343-I347 VanDerWaalsContact O-CG1 3.26Å; G343-I347 WeakPolarHBondContact O-CG1 3.42Å
344	W	88.7	Confident	88.9	Confident	95 Å²	95	21.2 Å²	21.2	36%	0.36	10%	0.104	S	C	.	.	H	α-helix	trans	-80.3	-44.9	-173.7	-61.2	37.3	0	0	0	110.5	T188 T189 T192 R312 G346 I347 F348	T188-W344 PolarHBondContact O-N 2.91Å; T189-W344 HydrophobicContact CG2-CB 3.96Å; T189-W344 HydrophobicContact CG2-CD2 3.7Å; T189-W344 HydrophobicContact CG2-CE3 4.18Å; T189-W344 HydrophobicContact CG2-CG 3.6Å; T192-W344 PolarHBondContact OG1-O 3.21Å; R312-W344 VanDerWaalsContact NH1-CD1 3.34Å; R312-W344 VanDerWaalsContact NH1-NE1 3.14Å; W344-G346 VanDerWaalsContact C-N 3.34Å; W344-G346 PolarHBondContact O-N 3.29Å; W344-I347 PolarHBondContact O-N 3.4Å; W344-F348 WeakPolarHBondContact O-CB 3.45Å; W344-F348 PolarHBondContact O-N 3.03Å
345	D	89.8	Confident	88.9	Confident	5 Å²	5	26 Å²	26	3%	0.027	13%	0.125	C	C	.	.	H	α-helix	trans	-62.1	-39	-179.4	-70.5	-8.7	0	0	0	112.4	I164 T188 T189 R190 I191 T192 F348 L349	I164-D345 HydrophobicContact CD1-CB 4.5Å; I164-D345 HydrophobicContact CG2-CB 4.3Å; T188-D345 VanDerWaalsContact O-CB 3.26Å; T188-D345 WeakPolarHBondContact O-CB 3.44Å; T188-D345 PolarHBondContact O-N 3.34Å; T189-D345 VanDerWaalsContact C-OD1 3.23Å; T189-D345 WeakPolarHBondContact CA-OD1 3.31Å; T189-D345 PolarHBondContact N-OD2 3.12Å; R190-D345 PolarHBondContact N-OD2 3.06Å; I191-D345 HydrophobicContact CB-CB 4.29Å; I191-D345 PolarHBondContact N-OD1 3.35Å; I191-D345 PolarHBondContact N-OD2 3.43Å; I191-D345 VanDerWaalsContact N-OD2 3.15Å; T192-D345 VanDerWaalsContact CB-OD1 3.3Å; T192-D345 WeakPolarHBondContact CB-OD1 3.39Å; T192-D345 PolarHBondContact N-OD1 3.2Å; T192-D345 WeakPolarHBondContact OG1-CA 3.45Å; T192-D345 PolarHBondContact OG1-N 3.49Å; T192-D345 PolarHBondContact OG1-OD1 3.01Å; D345-F348 PolarHBondContact O-N 2.75Å; D345-L349 WeakPolarHBondContact O-CB 3.38Å; D345-L349 PolarHBondContact O-N 3.38Å
346	G	90.8	Very high	88.8	Confident	0 Å²	0	26.4 Å²	26.4	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-67.1	-37.4	177.1	0	0	0	0	0	112.7	L161 L342 W344 L349 L350	L161-G346 VanDerWaalsContact CD2-CA 3.42Å; L342-G346 WeakPolarHBondContact O-CA 3.38Å; L342-G346 PolarHBondContact O-N 3.36Å; W344-G346 VanDerWaalsContact C-N 3.34Å; W344-G346 PolarHBondContact O-N 3.29Å; G346-L349 PolarHBondContact O-N 3.41Å; G346-L350 WeakPolarHBondContact O-CG 3.45Å; G346-L350 PolarHBondContact O-N 3.22Å
347	I	91.9	Very high	88.6	Confident	0 Å²	0	22.5 Å²	22.5	0%	0	11%	0.112	C	C	.	.	H	α-helix	trans	-72.6	-41.4	177.2	-63.7	162.6	0	0	0	110.7	R312 V338 L342 G343 W344 L349 L350 Q351	R312-I347 HydrophobicContact CB-CD1 3.85Å; R312-I347 HydrophobicContact CG-CD1 3.97Å; R312-I347 HydrophobicContact CG-CG2 4.18Å; V338-I347 HydrophobicContact CG1-CD1 3.46Å; V338-I347 VanDerWaalsContact CG1-CD1 3.46Å; V338-I347 HydrophobicContact CG1-CG1 4.31Å; L342-I347 HydrophobicContact CD2-CD1 4.43Å; L342-I347 HydrophobicContact CD2-CG1 3.46Å; L342-I347 VanDerWaalsContact CD2-CG1 3.46Å; L342-I347 HydrophobicContact CG-CG1 3.95Å; G343-I347 WeakPolarHBondContact O-CD1 3.35Å; G343-I347 VanDerWaalsContact O-CG1 3.26Å; G343-I347 WeakPolarHBondContact O-CG1 3.42Å; W344-I347 PolarHBondContact O-N 3.4Å; I347-L349 VanDerWaalsContact C-N 3.31Å; I347-L349 PolarHBondContact O-N 3.36Å; I347-L350 PolarHBondContact O-N 2.83Å; I347-Q351 HydrophobicContact CG2-CG 4.32Å; I347-Q351 WeakPolarHBondContact O-CB 3.4Å; I347-Q351 VanDerWaalsContact O-CG 3.3Å; I347-Q351 WeakPolarHBondContact O-CG 3.29Å; I347-Q351 PolarHBondContact O-N 2.95Å
348	F	92.1	Very high	88.5	Confident	1 Å²	1	24 Å²	24	0%	0.004	12%	0.124	C	C	.	.	H	α-helix	trans	-55	-48.9	172	165.2	-104.6	0	0	0	111	V22 W125 V132 I191 T192 F195 W302 L306 W344 D345 Q351 A352	V22-F348 HydrophobicContact CG2-CZ 4.48Å; W125-F348 AromaticContact CH2-CE1 3.97Å; W125-F348 HydrophobicContact CH2-CE1 3.97Å; W125-F348 AromaticContact CH2-CZ 3.8Å; W125-F348 HydrophobicContact CH2-CZ 3.8Å; W125-F348 HydrophobicContact CZ2-CZ 4.24Å; V132-F348 HydrophobicContact CG1-CE1 4.31Å; I191-F348 HydrophobicContact CG2-CD1 3.88Å; I191-F348 HydrophobicContact CG2-CE1 3.72Å; T192-F348 HydrophobicContact CG2-CB 4.44Å; F195-F348 HydrophobicContact CB-CE2 4.04Å; F195-F348 HydrophobicContact CB-CZ 3.97Å; F195-F348 HydrophobicContact CD1-CD2 4.02Å; F195-F348 AromaticContact CD1-CE2 3.41Å; F195-F348 HydrophobicContact CD1-CE2 3.41Å; F195-F348 VanDerWaalsContact CD1-CE2 3.41Å; F195-F348 HydrophobicContact CD1-CZ 4.15Å; F195-F348 AromaticContact CD2-CE2 3.76Å; F195-F348 HydrophobicContact CD2-CE2 3.76Å; F195-F348 AromaticContact CD2-CZ 3.74Å; F195-F348 HydrophobicContact CD2-CZ 3.74Å; F195-F348 HydrophobicContact CE1-CD2 4.29Å; F195-F348 AromaticContact CE1-CE2 3.62Å; F195-F348 HydrophobicContact CE1-CE2 3.62Å; F195-F348 AromaticContact CE2-CE2 3.97Å; F195-F348 HydrophobicContact CE2-CE2 3.97Å; F195-F348 HydrophobicContact CE2-CZ 4.19Å; F195-F348 HydrophobicContact CG-CD2 4.35Å; F195-F348 AromaticContact CG-CE2 3.46Å; F195-F348 HydrophobicContact CG-CE2 3.46Å; F195-F348 VanDerWaalsContact CG-CE2 3.46Å; F195-F348 AromaticContact CG-CZ 3.69Å; F195-F348 HydrophobicContact CG-CZ 3.69Å; F195-F348 AromaticContact CZ-CE2 3.86Å; F195-F348 HydrophobicContact CZ-CE2 3.86Å; W302-F348 HydrophobicContact CE3-CD2 4.37Å; W302-F348 HydrophobicContact CH2-CD2 4.36Å; W302-F348 HydrophobicContact CH2-CE2 4.3Å; W302-F348 AromaticContact CZ3-CD2 3.78Å; W302-F348 HydrophobicContact CZ3-CD2 3.78Å; W302-F348 HydrophobicContact CZ3-CE2 4.09Å; L306-F348 HydrophobicContact CD1-CD2 4.31Å; L306-F348 HydrophobicContact CD2-CB 3.76Å; L306-F348 HydrophobicContact CD2-CD2 4.35Å; W344-F348 WeakPolarHBondContact O-CB 3.45Å; W344-F348 PolarHBondContact O-N 3.03Å; D345-F348 PolarHBondContact O-N 2.75Å; F348-Q351 PolarHBondContact O-N 3.41Å; F348-A352 WeakPolarHBondContact O-CB 3.45Å; F348-A352 PolarHBondContact O-N 2.83Å
349	L	91.1	Very high	88.4	Confident	7 Å²	7	28.2 Å²	28.2	4%	0.037	15%	0.146	C	C	.	.	H	α-helix	trans	-62.7	-45.2	-179.9	-179	60.9	0	0	0	111.8	L135 L136 L157 L161 D345 G346 I347 Q351 A352 V353	L135-L349 HydrophobicContact CD2-CD1 3.84Å; L135-L349 HydrophobicContact CD2-CD2 3.5Å; L135-L349 VanDerWaalsContact CD2-CD2 3.5Å; L135-L349 HydrophobicContact CD2-CG 4.28Å; L135-L349 HydrophobicContact CG-CD1 4.39Å; L136-L349 HydrophobicContact CD2-CD1 3.91Å; L157-L349 HydrophobicContact CD2-CD2 4.47Å; L161-L349 HydrophobicContact CD2-CB 4.28Å; L161-L349 HydrophobicContact CD2-CD2 3.75Å; L161-L349 HydrophobicContact CD2-CG 4.42Å; L161-L349 HydrophobicContact CG-CD2 3.97Å; D345-L349 WeakPolarHBondContact O-CB 3.38Å; D345-L349 PolarHBondContact O-N 3.38Å; G346-L349 PolarHBondContact O-N 3.41Å; I347-L349 VanDerWaalsContact C-N 3.31Å; I347-L349 PolarHBondContact O-N 3.36Å; L349-Q351 PolarHBondContact O-N 2.88Å; L349-A352 PolarHBondContact O-N 3.36Å; L349-V353 HydrophobicContact CD1-CG2 4.24Å; L349-V353 WeakPolarHBondContact O-CB 3.46Å; L349-V353 VanDerWaalsContact O-CG2 3.23Å; L349-V353 WeakPolarHBondContact O-CG2 3.26Å; L349-V353 PolarHBondContact O-N 2.98Å
350	L	91.9	Very high	88.4	Confident	4 Å²	4	29.7 Å²	29.7	2%	0.021	15%	0.153	C	C	.	.	H	α-helix	trans	-63.1	-40.8	176.5	-70.3	175.7	0	0	0	112.4	L161 F315 I316 L342 G346 I347 V353 S354 V362 V365	L161-L350 HydrophobicContact CD1-CD2 3.66Å; L161-L350 HydrophobicContact CD1-CG 4.05Å; F315-L350 HydrophobicContact CE1-CB 4.2Å; I316-L350 HydrophobicContact CD1-CD1 3.63Å; L342-L350 HydrophobicContact CD1-CD1 4.31Å; L342-L350 HydrophobicContact CD2-CD1 3.78Å; G346-L350 WeakPolarHBondContact O-CG 3.45Å; G346-L350 PolarHBondContact O-N 3.22Å; I347-L350 PolarHBondContact O-N 2.83Å; L350-V353 PolarHBondContact O-N 2.93Å; L350-S354 WeakPolarHBondContact O-CB 3.44Å; L350-S354 PolarHBondContact O-N 2.87Å; L350-V362 HydrophobicContact CB-CG1 4.36Å; L350-V362 HydrophobicContact CD2-CG1 4.3Å; L350-V362 WeakPolarHBondContact O-CG2 3.36Å; L350-V365 HydrophobicContact CD2-CB 4.42Å; L350-V365 HydrophobicContact CD2-CG1 3.74Å
351	Q	91.7	Very high	88.6	Confident	14 Å²	14	27.4 Å²	27.4	7%	0.065	14%	0.141	C	C	.	.	H	α-helix	trans	-65.5	-40.3	175.7	-74	179.9	5.1	0	0	112.1	W302 F315 I347 F348 L349 S354 K355	W302-Q351 HydrophobicContact CH2-CB 4.01Å; W302-Q351 HydrophobicContact CZ3-CB 3.85Å; F315-Q351 HydrophobicContact CD1-CG 4.15Å; F315-Q351 HydrophobicContact CE1-CG 3.75Å; F315-Q351 HydrophobicContact CE2-CG 4.12Å; F315-Q351 HydrophobicContact CZ-CG 3.72Å; I347-Q351 HydrophobicContact CG2-CG 4.32Å; I347-Q351 WeakPolarHBondContact O-CB 3.4Å; I347-Q351 VanDerWaalsContact O-CG 3.3Å; I347-Q351 WeakPolarHBondContact O-CG 3.29Å; I347-Q351 PolarHBondContact O-N 2.95Å; F348-Q351 PolarHBondContact O-N 3.41Å; L349-Q351 PolarHBondContact O-N 2.88Å; Q351-S354 PolarHBondContact O-N 3.26Å; Q351-K355 PolarHBondContact O-N 3.03Å
352	A	91	Very high	89	Confident	0 Å²	0	26.4 Å²	26.4	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-63.8	-43	175.6	0	0	0	0	0	111.5	V22 L136 W302 F348 L349 K355 I356	V22-A352 HydrophobicContact CG1-CB 3.72Å; L136-A352 HydrophobicContact CD1-CB 4.29Å; L136-A352 HydrophobicContact CD2-CB 3.82Å; W302-A352 HydrophobicContact CH2-CB 4.38Å; F348-A352 WeakPolarHBondContact O-CB 3.45Å; F348-A352 PolarHBondContact O-N 2.83Å; L349-A352 PolarHBondContact O-N 3.36Å; A352-K355 PolarHBondContact O-N 3.43Å; A352-I356 WeakPolarHBondContact O-CG1 3.45Å; A352-I356 PolarHBondContact O-N 2.71Å; A352-I356 VanDerWaalsContact O-N 3.11Å
353	V	90.1	Very high	89.2	Confident	1 Å²	1	27.8 Å²	27.8	1%	0.006	14%	0.143	C	C	.	.	H	α-helix	trans	-65.3	-43.7	177.3	172.1	0	0	0	0	111.5	L136 A139 L157 L349 L350 K355 I356 S357 I361 V362	L136-V353 HydrophobicContact CD2-CG2 3.75Å; A139-V353 HydrophobicContact CB-CG1 4.15Å; A139-V353 HydrophobicContact CB-CG2 4.15Å; L157-V353 HydrophobicContact CD1-CG1 4.17Å; L157-V353 HydrophobicContact CD1-CG2 4.37Å; L157-V353 HydrophobicContact CD2-CG2 3.77Å; L349-V353 HydrophobicContact CD1-CG2 4.24Å; L349-V353 WeakPolarHBondContact O-CB 3.46Å; L349-V353 VanDerWaalsContact O-CG2 3.23Å; L349-V353 WeakPolarHBondContact O-CG2 3.26Å; L349-V353 PolarHBondContact O-N 2.98Å; L350-V353 PolarHBondContact O-N 2.93Å; V353-K355 PolarHBondContact O-N 3.41Å; V353-I356 PolarHBondContact O-N 2.69Å; V353-S357 WeakPolarHBondContact CG1-OG 3.2Å; V353-S357 PolarHBondContact O-N 3.35Å; V353-S357 PolarHBondContact O-OG 2.92Å; V353-I361 HydrophobicContact CG1-CG2 4.15Å; V353-V362 HydrophobicContact CB-CG2 4.06Å; V353-V362 HydrophobicContact CG1-CG2 3.75Å
354	S	89.6	Confident	89.3	Confident	28 Å²	28	29.8 Å²	29.8	20%	0.196	15%	0.153	C	C	.	.	H	α-helix	trans	-54.6	-40.5	174.9	158.6	0	0	0	0	111	Y319 L350 Q351 D359	Y319-S354 PolarHBondContact OH-OG 3.3Å; L350-S354 WeakPolarHBondContact O-CB 3.44Å; L350-S354 PolarHBondContact O-N 2.87Å; Q351-S354 PolarHBondContact O-N 3.26Å; S354-D359 WeakPolarHBondContact CB-OD1 3.26Å; S354-D359 PolarHBondContact OG-OD1 3.1Å
355	K	86.9	Confident	89.5	Confident	102 Å²	102	25.3 Å²	25.3	44%	0.443	14%	0.136	S	C	.	.	H	α-helix	trans	-76.7	-31.7	-177.2	-143.2	177.3	-172.7	176.8	0	114.5	D23 W302 Q351 A352 V353	D23-K355 WeakPolarHBondContact OD1-CD 3.42Å; D23-K355 VanDerWaalsContact OD1-CE 3.26Å; D23-K355 WeakPolarHBondContact OD1-CE 3.44Å; D23-K355 IonicContact OD1-NZ 3.73Å; D23-K355 PolarHBondContact OD1-NZ 3.49Å; W302-K355 HydrophobicContact CZ2-CD 4.32Å; Q351-K355 PolarHBondContact O-N 3.03Å; A352-K355 PolarHBondContact O-N 3.43Å; V353-K355 PolarHBondContact O-N 3.41Å
356	I	85.4	Confident	89.6	Confident	39 Å²	39	25.1 Å²	25.1	20%	0.2	14%	0.135	C	C	.	.	H	α-helix	trans	-88.9	-37.5	-175.5	-70.7	171.8	0	0	0	112.6	L136 R140 A352 V353	L136-I356 HydrophobicContact CB-CD1 3.84Å; L136-I356 HydrophobicContact CD1-CD1 3.82Å; L136-I356 HydrophobicContact CD2-CD1 4.05Å; L136-I356 HydrophobicContact CG-CD1 4.1Å; R140-I356 HydrophobicContact CB-CG2 3.58Å; R140-I356 HydrophobicContact CG-CG2 3.77Å; A352-I356 WeakPolarHBondContact O-CG1 3.45Å; A352-I356 PolarHBondContact O-N 2.71Å; A352-I356 VanDerWaalsContact O-N 3.11Å; V353-I356 PolarHBondContact O-N 2.69Å
357	S	83.3	Confident	89.7	Confident	25 Å²	25	25.3 Å²	25.3	18%	0.175	14%	0.138	C	C	.	.	S	Bend	trans	-110.5	-99.1	-168.1	64.2	0	0	0	0	111.2	A139 V353	A139-S357 VanDerWaalsContact O-CB 3.28Å; A139-S357 WeakPolarHBondContact O-CB 3.04Å; V353-S357 WeakPolarHBondContact CG1-OG 3.2Å; V353-S357 PolarHBondContact O-N 3.35Å; V353-S357 PolarHBondContact O-OG 2.92Å
358	S	85	Confident	89.6	Confident	41 Å²	41	29 Å²	29	29%	0.287	16%	0.155	S	C	.	.			trans	-151.8	155.8	170.3	63.1	0	0	0	0	110.3	L360 I361	S358-L360 PolarHBondContact O-N 2.99Å; S358-I361 PolarHBondContact O-N 3.45Å
359	D	88.3	Confident	89.6	Confident	88 Å²	88	29.6 Å²	29.6	47%	0.471	16%	0.159	S	C	.	.	H	α-helix	trans	-61.1	-21.3	172.6	-75.4	-35.1	0	0	0	112.9	Y319 S354 V362 L363	Y319-D359 HydrophobicContact CE1-CB 4.07Å; Y319-D359 PolarHBondContact OH-OD1 2.97Å; S354-D359 WeakPolarHBondContact CB-OD1 3.26Å; S354-D359 PolarHBondContact OG-OD1 3.1Å; D359-V362 PolarHBondContact O-N 3Å; D359-L363 VanDerWaalsContact O-CB 3.31Å; D359-L363 WeakPolarHBondContact O-CB 3.45Å; D359-L363 PolarHBondContact O-N 3.39Å
360	L	87.4	Confident	89.6	Confident	92 Å²	92	29.2 Å²	29.2	48%	0.482	16%	0.157	S	C	.	.	H	α-helix	trans	-66.2	-40.9	177.7	-173.3	66.1	0	0	0	112.2	S358 V362 L363 D364	S358-L360 PolarHBondContact O-N 2.99Å; L360-V362 VanDerWaalsContact C-N 3.33Å; L360-L363 WeakPolarHBondContact O-CB 3.38Å; L360-L363 PolarHBondContact O-N 2.97Å; L360-D364 PolarHBondContact O-N 3.37Å
361	I	87.7	Confident	89.5	Confident	3 Å²	3	30.9 Å²	30.9	2%	0.015	17%	0.169	C	C	.	.	H	α-helix	trans	-65.8	-41.8	177.5	-63.9	178.4	0	0	0	109.9	A142 I154 L157 V353 S358 L363 D364 V365	A142-I361 HydrophobicContact CB-CD1 4.04Å; I154-I361 HydrophobicContact CG1-CG2 4.13Å; L157-I361 HydrophobicContact CD1-CG2 3.97Å; V353-I361 HydrophobicContact CG1-CG2 4.15Å; S358-I361 PolarHBondContact O-N 3.45Å; I361-L363 VanDerWaalsContact C-N 3.31Å; I361-L363 PolarHBondContact O-N 3.47Å; I361-D364 PolarHBondContact O-N 3.18Å; I361-V365 HydrophobicContact CG2-CG2 4.29Å; I361-V365 WeakPolarHBondContact O-CB 3.4Å; I361-V365 WeakPolarHBondContact O-CG2 3.42Å; I361-V365 PolarHBondContact O-N 3.36Å
362	V	91.4	Very high	89.4	Confident	0 Å²	0	32.7 Å²	32.7	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-65.4	-37.3	177.5	175.9	0	0	0	0	111.5	F315 Y319 L350 V353 D359 L360 T366	F315-V362 HydrophobicContact CZ-CG1 4.48Å; Y319-V362 HydrophobicContact CD1-CG1 4.26Å; Y319-V362 HydrophobicContact CD2-CG1 4.27Å; Y319-V362 HydrophobicContact CE1-CB 4.12Å; Y319-V362 HydrophobicContact CE1-CG1 3.9Å; Y319-V362 HydrophobicContact CE2-CG1 3.94Å; Y319-V362 HydrophobicContact CG-CG1 4.43Å; L350-V362 HydrophobicContact CB-CG1 4.36Å; L350-V362 HydrophobicContact CD2-CG1 4.3Å; L350-V362 WeakPolarHBondContact O-CG2 3.36Å; V353-V362 HydrophobicContact CB-CG2 4.06Å; V353-V362 HydrophobicContact CG1-CG2 3.75Å; D359-V362 PolarHBondContact O-N 3Å; L360-V362 VanDerWaalsContact C-N 3.33Å; V362-T366 WeakPolarHBondContact O-CB 3.3Å; V362-T366 PolarHBondContact O-N 2.95Å; V362-T366 PolarHBondContact O-OG1 3.34Å
363	L	91.8	Very high	89.3	Confident	37 Å²	37	34.6 Å²	34.6	19%	0.194	19%	0.186	C	C	.	.	H	α-helix	trans	-60	-54.1	174	-174.8	148.7	0	0	0	110.8	Y319 A322 L323 D359 L360 I361 V365 T366 G367	Y319-L363 HydrophobicContact CD1-CB 3.96Å; A322-L363 HydrophobicContact CB-CD1 4.02Å; L323-L363 HydrophobicContact CD1-CD2 4.23Å; L323-L363 HydrophobicContact CD1-CG 4.22Å; L323-L363 WeakPolarHBondContact CD1-O 3.5Å; L323-L363 HydrophobicContact CD2-CD2 3.33Å; L323-L363 HydrophobicContact CD2-CG 4.07Å; L323-L363 HydrophobicContact CG-CD1 4.49Å; L323-L363 HydrophobicContact CG-CD2 3.69Å; L323-L363 HydrophobicContact CG-CG 3.83Å; D359-L363 VanDerWaalsContact O-CB 3.31Å; D359-L363 WeakPolarHBondContact O-CB 3.45Å; D359-L363 PolarHBondContact O-N 3.39Å; L360-L363 WeakPolarHBondContact O-CB 3.38Å; L360-L363 PolarHBondContact O-N 2.97Å; I361-L363 VanDerWaalsContact C-N 3.31Å; I361-L363 PolarHBondContact O-N 3.47Å; L363-V365 PolarHBondContact O-N 2.96Å; L363-T366 PolarHBondContact O-N 2.94Å; L363-G367 PolarHBondContact O-N 2.84Å
364	D	90.7	Very high	89.2	Confident	43 Å²	43	37.4 Å²	37.4	23%	0.23	20%	0.199	C	C	.	.	H	α-helix	trans	-57.9	-47.6	178.4	-76.3	-9.1	0	0	0	111.7	R150 I154 L360 I361 T366 G367 M368	R150-D364 IonicContact CZ-OD2 3.73Å; R150-D364 IonicContact NE-OD2 3.87Å; R150-D364 IonicContact NH2-OD2 2.94Å; R150-D364 PolarHBondContact NH2-OD2 3.39Å; I154-D364 HydrophobicContact CD1-CB 3.97Å; L360-D364 PolarHBondContact O-N 3.37Å; I361-D364 PolarHBondContact O-N 3.18Å; D364-T366 PolarHBondContact O-N 3.29Å; D364-G367 PolarHBondContact O-N 3.01Å; D364-M368 WeakPolarHBondContact O-CG 3.49Å; D364-M368 PolarHBondContact O-N 3Å
365	V	92	Very high	89.2	Confident	1 Å²	1	43.5 Å²	43.5	1%	0.006	22%	0.218	C	C	.	.	H	α-helix	trans	-62.3	-44.7	179.1	170.8	0	0	0	0	111.4	I154 L157 V158 L161 L350 I361 L363 M368 L369	I154-V365 HydrophobicContact CB-CG2 4.4Å; I154-V365 HydrophobicContact CG1-CG2 4.29Å; I154-V365 HydrophobicContact CG2-CG2 3.94Å; L157-V365 HydrophobicContact CB-CG2 4.17Å; L157-V365 HydrophobicContact CD1-CG2 4.23Å; V158-V365 HydrophobicContact CG2-CB 4.35Å; V158-V365 HydrophobicContact CG2-CG1 3.91Å; V158-V365 HydrophobicContact CG2-CG2 4.26Å; L161-V365 HydrophobicContact CD1-CG1 3.72Å; L350-V365 HydrophobicContact CD2-CB 4.42Å; L350-V365 HydrophobicContact CD2-CG1 3.74Å; I361-V365 HydrophobicContact CG2-CG2 4.29Å; I361-V365 WeakPolarHBondContact O-CB 3.4Å; I361-V365 WeakPolarHBondContact O-CG2 3.42Å; I361-V365 PolarHBondContact O-N 3.36Å; L363-V365 PolarHBondContact O-N 2.96Å; V365-M368 PolarHBondContact O-N 3.48Å; V365-L369 HydrophobicContact CG1-CD1 3.86Å; V365-L369 HydrophobicContact CG1-CG 4.45Å; V365-L369 VanDerWaalsContact O-CG 3.29Å; V365-L369 WeakPolarHBondContact O-CG 3.37Å; V365-L369 PolarHBondContact O-N 2.75Å
366	T	92.6	Very high	89.2	Confident	1 Å²	1	41.2 Å²	41.2	1%	0.006	22%	0.218	C	C	.	.	H	α-helix	trans	-66.2	-39.7	-178.8	-57.6	0	0	0	0	111.2	I316 L320 V362 L363 D364 L369 W370	I316-T366 HydrophobicContact CD1-CG2 4.37Å; I316-T366 HydrophobicContact CG2-CG2 3.9Å; L320-T366 HydrophobicContact CD2-CG2 3.87Å; L320-T366 HydrophobicContact CG-CG2 4.08Å; V362-T366 WeakPolarHBondContact O-CB 3.3Å; V362-T366 PolarHBondContact O-N 2.95Å; V362-T366 PolarHBondContact O-OG1 3.34Å; L363-T366 PolarHBondContact O-N 2.94Å; D364-T366 PolarHBondContact O-N 3.29Å; T366-L369 PolarHBondContact O-N 3.11Å; T366-W370 WeakPolarHBondContact O-CB 3.49Å; T366-W370 PolarHBondContact O-N 2.94Å
367	G	91.4	Very high	89.1	Confident	5 Å²	5	43.2 Å²	43.2	5%	0.052	23%	0.226	C	C	.	.	H	α-helix	trans	-64.2	-44.2	175.1	0	0	0	0	0	112.9	L363 D364 W370 S371	L363-G367 PolarHBondContact O-N 2.84Å; D364-G367 PolarHBondContact O-N 3.01Å; G367-W370 PolarHBondContact O-N 2.85Å; G367-S371 PolarHBondContact O-N 3.06Å; G367-S371 PolarHBondContact O-OG 2.98Å
368	M	91	Very high	89.3	Confident	76 Å²	76	46.6 Å²	46.6	37%	0.374	24%	0.241	S	C	.	.	H	α-helix	trans	-59.8	-47.9	174.5	-76.1	179.6	55.6	0	0	111.9	I154 V158 D364 V365 W370 S371 N372	I154-M368 HydrophobicContact CG2-CE 4.37Å; I154-M368 HydrophobicContact CG2-SD 3.55Å; I154-M368 VanDerWaalsContact CG2-SD 3.55Å; V158-M368 HydrophobicContact CB-CE 4.28Å; V158-M368 HydrophobicContact CG1-CE 4.17Å; V158-M368 HydrophobicContact CG2-CB 4.22Å; V158-M368 HydrophobicContact CG2-CE 3.81Å; V158-M368 HydrophobicContact CG2-SD 4.26Å; D364-M368 WeakPolarHBondContact O-CG 3.49Å; D364-M368 PolarHBondContact O-N 3Å; V365-M368 PolarHBondContact O-N 3.48Å; M368-W370 VanDerWaalsContact C-N 3.32Å; M368-W370 PolarHBondContact O-N 3.39Å; M368-S371 PolarHBondContact O-N 3.26Å; M368-S371 PolarHBondContact O-OG 3.41Å; M368-N372 WeakPolarHBondContact O-CB 3.34Å; M368-N372 PolarHBondContact O-N 3.02Å
369	L	91.5	Very high	89.4	Confident	14 Å²	14	47.5 Å²	47.5	7%	0.073	25%	0.245	C	C	.	.	H	α-helix	trans	-63	-38	179	-70.4	168.5	0	0	0	112.8	V158 L161 E162 F337 V365 T366 Y373	V158-L369 HydrophobicContact CG1-CD2 4.04Å; L161-L369 HydrophobicContact CB-CD1 4.04Å; L161-L369 HydrophobicContact CB-CD2 4.13Å; L161-L369 HydrophobicContact CD1-CD1 3.57Å; L161-L369 HydrophobicContact CG-CD1 4.4Å; E162-L369 HydrophobicContact CG-CD2 3.9Å; F337-L369 HydrophobicContact CZ-CB 3.94Å; V365-L369 HydrophobicContact CG1-CD1 3.86Å; V365-L369 HydrophobicContact CG1-CG 4.45Å; V365-L369 VanDerWaalsContact O-CG 3.29Å; V365-L369 WeakPolarHBondContact O-CG 3.37Å; V365-L369 PolarHBondContact O-N 2.75Å; T366-L369 PolarHBondContact O-N 3.11Å; L369-Y373 WeakPolarHBondContact O-CB 3.44Å; L369-Y373 PolarHBondContact O-N 3.33Å
370	W	91.1	Very high	89.1	Confident	0 Å²	0	44.4 Å²	44.4	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-66.9	-46.2	177.3	180	-108.4	0	0	0	112.1	L320 L326 E330 E333 C334 F337 T366 G367 M368 N372 Y373 Q374	L320-W370 HydrophobicContact CD1-CD2 3.97Å; L320-W370 HydrophobicContact CD1-CE3 4.02Å; L320-W370 HydrophobicContact CD1-CG 4.22Å; L320-W370 HydrophobicContact CD2-CB 3.62Å; L320-W370 HydrophobicContact CD2-CD2 4.37Å; L320-W370 HydrophobicContact CD2-CG 3.75Å; L326-W370 HydrophobicContact CD1-CH2 4.39Å; L326-W370 HydrophobicContact CD1-CZ2 4.03Å; E330-W370 HydrophobicContact CB-CZ2 4.43Å; E333-W370 HydrophobicContact CB-CH2 4.16Å; C334-W370 HydrophobicContact CB-CH2 4.41Å; C334-W370 HydrophobicContact CB-CZ3 4.47Å; F337-W370 HydrophobicContact CB-CE3 4.19Å; F337-W370 HydrophobicContact CB-CZ3 3.68Å; F337-W370 AromaticContact CD1-CE3 3.77Å; F337-W370 HydrophobicContact CD1-CE3 3.77Å; F337-W370 HydrophobicContact CD1-CZ3 4.04Å; F337-W370 HydrophobicContact CD2-CE3 4.3Å; F337-W370 HydrophobicContact CE1-CE3 4.2Å; F337-W370 AromaticContact CG-CE3 3.83Å; F337-W370 HydrophobicContact CG-CE3 3.83Å; F337-W370 AromaticContact CG-CZ3 3.85Å; F337-W370 HydrophobicContact CG-CZ3 3.85Å; T366-W370 WeakPolarHBondContact O-CB 3.49Å; T366-W370 PolarHBondContact O-N 2.94Å; G367-W370 PolarHBondContact O-N 2.85Å; M368-W370 VanDerWaalsContact C-N 3.32Å; M368-W370 PolarHBondContact O-N 3.39Å; W370-N372 PolarHBondContact O-N 3.21Å; W370-Y373 HydrophobicContact CE3-CD1 4.07Å; W370-Y373 AromaticContact CZ3-CD1 3.91Å; W370-Y373 HydrophobicContact CZ3-CD1 3.91Å; W370-Y373 HydrophobicContact CZ3-CE1 4.11Å; W370-Y373 WeakPolarHBondContact O-CB 3.29Å; W370-Y373 PolarHBondContact O-N 3.01Å; W370-Q374 HydrophobicContact CZ2-CG 4.39Å; W370-Q374 PolarHBondContact O-N 3.17Å
371	S	90.3	Very high	88.8	Confident	38 Å²	38	43.2 Å²	43.2	27%	0.266	23%	0.23	S	C	.	.	H	α-helix	trans	-62.1	-41.2	175.9	65.7	0	0	0	0	112.7	G367 M368 Y373 Q374 R375	G367-S371 PolarHBondContact O-N 3.06Å; G367-S371 PolarHBondContact O-OG 2.98Å; M368-S371 PolarHBondContact O-N 3.26Å; M368-S371 PolarHBondContact O-OG 3.41Å; S371-Y373 VanDerWaalsContact C-N 3.31Å; S371-Y373 PolarHBondContact O-N 2.97Å; S371-Q374 PolarHBondContact O-N 2.75Å; S371-R375 WeakPolarHBondContact O-CB 3.46Å; S371-R375 PolarHBondContact O-N 3.2Å
372	N	89.8	Confident	88.4	Confident	52 Å²	52	48.9 Å²	48.9	28%	0.278	26%	0.256	S	S	.	.	H	α-helix	trans	-63.3	-38.7	174.8	-73.4	-6.4	0	0	0	111.4	E162 M368 W370 R375 A376	E162-N372 PolarHBondContact OE1-ND2 3.42Å; M368-N372 WeakPolarHBondContact O-CB 3.34Å; M368-N372 PolarHBondContact O-N 3.02Å; W370-N372 PolarHBondContact O-N 3.21Å; N372-R375 PolarHBondContact O-N 3.05Å; N372-A376 WeakPolarHBondContact O-CB 3.47Å; N372-A376 PolarHBondContact O-N 3.19Å
373	Y	88	Confident	87.8	Confident	40 Å²	40	54.5 Å²	54.5	16%	0.157	28%	0.283	C	S	.	.	H	α-helix	trans	-64.5	-46.4	174.9	172.9	-110.9	0	0	0	112.8	F337 N341 L369 W370 S371 R375 A376 K377	F337-Y373 HydrophobicContact CB-CD1 4.16Å; F337-Y373 HydrophobicContact CB-CE1 3.97Å; F337-Y373 AromaticContact CD2-CD1 3.77Å; F337-Y373 HydrophobicContact CD2-CD1 3.77Å; F337-Y373 AromaticContact CD2-CD2 3.99Å; F337-Y373 HydrophobicContact CD2-CD2 3.99Å; F337-Y373 HydrophobicContact CD2-CE1 4.34Å; F337-Y373 HydrophobicContact CD2-CE2 4.5Å; F337-Y373 AromaticContact CD2-CG 3.55Å; F337-Y373 HydrophobicContact CD2-CG 3.55Å; F337-Y373 HydrophobicContact CE2-CG 4.11Å; F337-Y373 HydrophobicContact CG-CD1 4.24Å; F337-Y373 HydrophobicContact CG-CG 4.45Å; N341-Y373 WeakPolarHBondContact ND2-CD2 3.4Å; N341-Y373 WeakPolarHBondContact ND2-CE2 3.25Å; L369-Y373 WeakPolarHBondContact O-CB 3.44Å; L369-Y373 PolarHBondContact O-N 3.33Å; W370-Y373 HydrophobicContact CE3-CD1 4.07Å; W370-Y373 AromaticContact CZ3-CD1 3.91Å; W370-Y373 HydrophobicContact CZ3-CD1 3.91Å; W370-Y373 HydrophobicContact CZ3-CE1 4.11Å; W370-Y373 WeakPolarHBondContact O-CB 3.29Å; W370-Y373 PolarHBondContact O-N 3.01Å; S371-Y373 VanDerWaalsContact C-N 3.31Å; S371-Y373 PolarHBondContact O-N 2.97Å; Y373-R375 VanDerWaalsContact C-N 3.34Å; Y373-R375 PolarHBondContact O-N 3.36Å; Y373-A376 PolarHBondContact O-N 3.45Å; Y373-K377 PolarHBondContact O-N 3.16Å; Y373-K377 VanDerWaalsContact O-N 3.1Å
374	Q	88.3	Confident	87.1	Confident	60 Å²	60	57 Å²	57	28%	0.28	30%	0.296	S	S	.	.	H	α-helix	trans	-60.4	-44.5	176.3	-75.3	-179.8	-29.8	0	0	111.1	E330 W370 S371 A376 K377 I378	E330-Q374 PolarHBondContact OE1-NE2 2.72Å; W370-Q374 HydrophobicContact CZ2-CG 4.39Å; W370-Q374 PolarHBondContact O-N 3.17Å; S371-Q374 PolarHBondContact O-N 2.75Å; Q374-A376 PolarHBondContact O-N 3.49Å; Q374-K377 WeakPolarHBondContact O-CB 3.4Å; Q374-K377 PolarHBondContact O-N 3.06Å; Q374-I378 WeakPolarHBondContact O-CG1 3.39Å; Q374-I378 PolarHBondContact O-N 2.99Å
375	R	89.2	Confident	86.5	Confident	157 Å²	157	59.3 Å²	59.3	59%	0.592	31%	0.307	S	S	*	.	H	α-helix	trans	-59.8	-48	177.6	-168	-178.4	-62.5	144.2	3.8	112	S371 N372 Y373 K377 I378 T379	S371-R375 WeakPolarHBondContact O-CB 3.46Å; S371-R375 PolarHBondContact O-N 3.2Å; N372-R375 PolarHBondContact O-N 3.05Å; Y373-R375 VanDerWaalsContact C-N 3.34Å; Y373-R375 PolarHBondContact O-N 3.36Å; R375-K377 PolarHBondContact O-N 3.49Å; R375-I378 PolarHBondContact O-N 3.2Å; R375-T379 PolarHBondContact O-N 3.27Å; R375-T379 PolarHBondContact O-OG1 2.93Å
376	A	86.2	Confident	86	Confident	54 Å²	54	60.7 Å²	60.7	45%	0.446	32%	0.322	S	S	.	.	H	α-helix	trans	-63.2	-27.9	178.4	0	0	0	0	0	113.4	N372 Y373 Q374 T379 G380	N372-A376 WeakPolarHBondContact O-CB 3.47Å; N372-A376 PolarHBondContact O-N 3.19Å; Y373-A376 PolarHBondContact O-N 3.45Å; Q374-A376 PolarHBondContact O-N 3.49Å; A376-T379 PolarHBondContact O-OG1 3.02Å; A376-G380 PolarHBondContact O-N 3.36Å; A376-G380 VanDerWaalsContact O-N 3.16Å
377	K	85.1	Confident	85.3	Confident	81 Å²	81	67.4 Å²	67.4	35%	0.352	35%	0.347	S	S	.	.	H	α-helix	trans	-73.8	-43.3	175	-175	-169	178.9	-163.2	0	111.4	E333 Y373 Q374 R375 G380 T381	E333-K377 IonicContact OE1-NZ 3.42Å; E333-K377 PolarHBondContact OE1-NZ 2.96Å; E333-K377 IonicContact OE2-NZ 3.6Å; E333-K377 PolarHBondContact OE2-NZ 3.47Å; Y373-K377 PolarHBondContact O-N 3.16Å; Y373-K377 VanDerWaalsContact O-N 3.1Å; Q374-K377 WeakPolarHBondContact O-CB 3.4Å; Q374-K377 PolarHBondContact O-N 3.06Å; R375-K377 PolarHBondContact O-N 3.49Å; K377-G380 PolarHBondContact O-N 3.01Å; K377-T381 WeakPolarHBondContact O-CB 3.47Å; K377-T381 PolarHBondContact O-N 3.41Å; K377-T381 PolarHBondContact O-OG1 3.07Å
378	I	87.3	Confident	84.8	Confident	96 Å²	96	73.3 Å²	73.3	49%	0.492	37%	0.372	S	S	.	.	H	α-helix	trans	-61	-51.9	178.2	-66.8	165.3	0	0	0	109.4	Q374 R375 G380 T381 E382	Q374-I378 WeakPolarHBondContact O-CG1 3.39Å; Q374-I378 PolarHBondContact O-N 2.99Å; R375-I378 PolarHBondContact O-N 3.2Å; I378-G380 VanDerWaalsContact C-N 3.34Å; I378-G380 PolarHBondContact O-N 3.41Å; I378-T381 WeakPolarHBondContact O-CA 3.44Å; I378-T381 WeakPolarHBondContact O-CB 3.37Å; I378-T381 PolarHBondContact O-N 3.12Å; I378-E382 WeakPolarHBondContact O-CG 3.46Å; I378-E382 PolarHBondContact O-N 3.5Å
379	T	87.3	Confident	84.5	Confident	60 Å²	60	74 Å²	74	37%	0.368	38%	0.376	S	S	.	.	H	α-helix	trans	-60.7	-42.2	178.9	58.4	0	0	0	0	112.2	R375 A376 T381 E382 E383	R375-T379 PolarHBondContact O-N 3.27Å; R375-T379 PolarHBondContact O-OG1 2.93Å; A376-T379 PolarHBondContact O-OG1 3.02Å; T379-T381 VanDerWaalsContact C-N 3.25Å; T379-T381 PolarHBondContact O-N 3.04Å; T379-E382 PolarHBondContact O-N 2.98Å; T379-E383 WeakPolarHBondContact O-CG 3.49Å; T379-E383 PolarHBondContact O-N 2.67Å
380	G	81.7	Confident	84.2	Confident	22 Å²	22	78.8 Å²	78.8	23%	0.227	40%	0.398	C	S	.	.	H	α-helix	trans	-65.1	-28.4	175.6	0	0	0	0	0	113.7	A376 K377 I378 N384	A376-G380 PolarHBondContact O-N 3.36Å; A376-G380 VanDerWaalsContact O-N 3.16Å; K377-G380 PolarHBondContact O-N 3.01Å; I378-G380 VanDerWaalsContact C-N 3.34Å; I378-G380 PolarHBondContact O-N 3.41Å; G380-N384 PolarHBondContact O-N 3.33Å; G380-N384 PolarHBondContact O-ND2 3.45Å
381	T	79.9	Confident	83.8	Confident	68 Å²	68	81.7 Å²	81.7	42%	0.417	42%	0.418	S	S	.	.	H	α-helix	trans	-74	-43.1	175.2	-54.2	0	0	0	0	110.5	K377 I378 T379 N384 I385	K377-T381 WeakPolarHBondContact O-CB 3.47Å; K377-T381 PolarHBondContact O-N 3.41Å; K377-T381 PolarHBondContact O-OG1 3.07Å; I378-T381 WeakPolarHBondContact O-CA 3.44Å; I378-T381 WeakPolarHBondContact O-CB 3.37Å; I378-T381 PolarHBondContact O-N 3.12Å; T379-T381 VanDerWaalsContact C-N 3.25Å; T379-T381 PolarHBondContact O-N 3.04Å; T381-N384 PolarHBondContact O-N 3.02Å; T381-I385 HydrophobicContact CG2-CD1 3.93Å; T381-I385 VanDerWaalsContact O-CG1 3.29Å; T381-I385 WeakPolarHBondContact O-CG1 3.5Å; T381-I385 PolarHBondContact O-N 3.37Å
382	E	79.6	Confident	83.5	Confident	122 Å²	122	84.1 Å²	84.1	57%	0.57	43%	0.427	S	S	*	.	H	α-helix	trans	-59.3	-45.2	174.4	-69.9	170.4	175	0	0	111.8	I378 T379 N384 I385 G386	I378-E382 WeakPolarHBondContact O-CG 3.46Å; I378-E382 PolarHBondContact O-N 3.5Å; T379-E382 PolarHBondContact O-N 2.98Å; E382-N384 VanDerWaalsContact C-N 3.33Å; E382-N384 PolarHBondContact O-N 3.1Å; E382-I385 PolarHBondContact O-N 3.16Å; E382-G386 PolarHBondContact O-N 2.97Å
383	E	78.5	Confident	83.2	Confident	118 Å²	118	87.8 Å²	87.8	55%	0.551	45%	0.447	S	S	*	.	H	α-helix	trans	-62.5	-37.9	175.7	-74	177.2	-170.8	0	0	113	T379 R387	T379-E383 WeakPolarHBondContact O-CG 3.49Å; T379-E383 PolarHBondContact O-N 2.67Å; E383-R387 WeakPolarHBondContact O-CB 3.48Å; E383-R387 WeakPolarHBondContact O-CG 3.41Å; E383-R387 PolarHBondContact O-N 3.47Å
384	N	76.8	Confident	82.7	Confident	89 Å²	89	96.1 Å²	96.1	48%	0.476	48%	0.478	S	S	.	.	H	α-helix	trans	-70.7	-39.6	177.9	-72.6	-26.1	0	0	0	111.5	G380 T381 E382 R387 F388	G380-N384 PolarHBondContact O-N 3.33Å; G380-N384 PolarHBondContact O-ND2 3.45Å; T381-N384 PolarHBondContact O-N 3.02Å; E382-N384 VanDerWaalsContact C-N 3.33Å; E382-N384 PolarHBondContact O-N 3.1Å; N384-R387 PolarHBondContact O-N 3.5Å; N384-R387 PolarHBondContact OD1-NH1 2.84Å; N384-R387 PolarHBondContact OD1-NH2 3.32Å; N384-F388 WeakPolarHBondContact O-CB 3.36Å; N384-F388 PolarHBondContact O-N 2.92Å
385	I	78.7	Confident	81.6	Confident	92 Å²	92	102.1 Å²	102.1	47%	0.472	52%	0.518	S	S	.	.	H	α-helix	trans	-64.1	-45.4	174.3	-68.4	166.8	0	0	0	109.9	T381 E382 R387 F388 I389	T381-I385 HydrophobicContact CG2-CD1 3.93Å; T381-I385 VanDerWaalsContact O-CG1 3.29Å; T381-I385 WeakPolarHBondContact O-CG1 3.5Å; T381-I385 PolarHBondContact O-N 3.37Å; E382-I385 PolarHBondContact O-N 3.16Å; I385-R387 PolarHBondContact O-N 3Å; I385-F388 WeakPolarHBondContact O-CB 3.29Å; I385-F388 PolarHBondContact O-N 3.42Å; I385-F388 VanDerWaalsContact O-N 3.16Å; I385-I389 HydrophobicContact CG2-CD1 3.83Å; I385-I389 HydrophobicContact CG2-CG1 4.45Å; I385-I389 WeakPolarHBondContact O-CG1 3.45Å; I385-I389 PolarHBondContact O-N 3.31Å
386	G	81.1	Confident	81.3	Confident	30 Å²	30	99.4 Å²	99.4	31%	0.309	51%	0.514	S	S	.	.	H	α-helix	trans	-57	-48.8	175.7	0	0	0	0	0	112.3	E382 F388 I389 E390	E382-G386 PolarHBondContact O-N 2.97Å; G386-F388 VanDerWaalsContact C-N 3.31Å; G386-F388 PolarHBondContact O-N 3.23Å; G386-I389 PolarHBondContact O-N 3.02Å; G386-E390 WeakPolarHBondContact O-CG 3.49Å; G386-E390 PolarHBondContact O-N 3.21Å
387	R	77.6	Confident	81	Confident	142 Å²	142	101.7 Å²	101.7	54%	0.536	52%	0.518	S	S	.	.	H	α-helix	trans	-62	-35.2	175.4	-80.8	-173.5	-91.4	130.3	-0.4	113.4	E383 N384 I385 S391	E383-R387 WeakPolarHBondContact O-CB 3.48Å; E383-R387 WeakPolarHBondContact O-CG 3.41Å; E383-R387 PolarHBondContact O-N 3.47Å; N384-R387 PolarHBondContact O-N 3.5Å; N384-R387 PolarHBondContact OD1-NH1 2.84Å; N384-R387 PolarHBondContact OD1-NH2 3.32Å; I385-R387 PolarHBondContact O-N 3Å; R387-S391 WeakPolarHBondContact O-CB 3.45Å; R387-S391 PolarHBondContact O-N 2.94Å
388	F	81	Confident	80.8	Confident	129 Å²	129	102.9 Å²	102.9	57%	0.566	53%	0.527	S	S	*	.	H	α-helix	trans	-67.4	-45.3	176.2	179.1	-108.1	0	0	0	111.6	N384 I385 G386 E390 S391 I392	N384-F388 WeakPolarHBondContact O-CB 3.36Å; N384-F388 PolarHBondContact O-N 2.92Å; I385-F388 WeakPolarHBondContact O-CB 3.29Å; I385-F388 PolarHBondContact O-N 3.42Å; I385-F388 VanDerWaalsContact O-N 3.16Å; G386-F388 VanDerWaalsContact C-N 3.31Å; G386-F388 PolarHBondContact O-N 3.23Å; F388-E390 VanDerWaalsContact C-N 3.33Å; F388-E390 PolarHBondContact O-N 2.97Å; F388-S391 PolarHBondContact O-N 2.96Å; F388-S391 VanDerWaalsContact O-N 3.1Å; F388-S391 PolarHBondContact O-OG 3.41Å; F388-I392 HydrophobicContact CD1-CD1 3.8Å; F388-I392 HydrophobicContact CE1-CD1 3.27Å; F388-I392 HydrophobicContact CE1-CG1 4.32Å; F388-I392 HydrophobicContact CE2-CD1 4.2Å; F388-I392 HydrophobicContact CE2-CG1 4.49Å; F388-I392 HydrophobicContact CG-CD1 4.48Å; F388-I392 HydrophobicContact CZ-CD1 3.51Å; F388-I392 HydrophobicContact CZ-CG1 4.22Å; F388-I392 PolarHBondContact O-N 3.29Å
389	I	84.8	Confident	80.4	Confident	89 Å²	89	103.3 Å²	103.3	46%	0.456	53%	0.529	S	S	.	.	H	α-helix	trans	-60.8	-43.4	175.9	-66	166.7	0	0	0	110.7	I385 G386 S391 I392 N393	I385-I389 HydrophobicContact CG2-CD1 3.83Å; I385-I389 HydrophobicContact CG2-CG1 4.45Å; I385-I389 WeakPolarHBondContact O-CG1 3.45Å; I385-I389 PolarHBondContact O-N 3.31Å; G386-I389 PolarHBondContact O-N 3.02Å; I389-S391 VanDerWaalsContact C-N 3.29Å; I389-S391 PolarHBondContact O-N 3.44Å; I389-I392 PolarHBondContact O-N 3.11Å; I389-N393 PolarHBondContact O-N 3.05Å
390	E	85.1	Confident	80	Confident	116 Å²	116	106 Å²	106	54%	0.542	54%	0.539	S	S	.	.	H	α-helix	trans	-61.1	-35.7	174.1	-74.6	178.7	-178.4	0	0	113	G386 F388 R394	G386-E390 WeakPolarHBondContact O-CG 3.49Å; G386-E390 PolarHBondContact O-N 3.21Å; F388-E390 VanDerWaalsContact C-N 3.33Å; F388-E390 PolarHBondContact O-N 2.97Å; E390-R394 WeakPolarHBondContact O-CG 3.47Å; E390-R394 PolarHBondContact O-N 3.29Å
391	S	83.4	Confident	79.8	Confident	61 Å²	61	111.6 Å²	111.6	43%	0.427	56%	0.56	S	S	.	*	H	α-helix	trans	-70.7	-35.5	177.7	74.2	0	0	0	0	113	R387 F388 I389 R394	R387-S391 WeakPolarHBondContact O-CB 3.45Å; R387-S391 PolarHBondContact O-N 2.94Å; F388-S391 PolarHBondContact O-N 2.96Å; F388-S391 VanDerWaalsContact O-N 3.1Å; F388-S391 PolarHBondContact O-OG 3.41Å; I389-S391 VanDerWaalsContact C-N 3.29Å; I389-S391 PolarHBondContact O-N 3.44Å; S391-R394 PolarHBondContact O-N 3.38Å
392	I	83.7	Confident	79.8	Confident	89 Å²	89	114.7 Å²	114.7	46%	0.456	57%	0.57	S	S	.	*	H	α-helix	trans	-66.9	-43.6	174.2	-69.8	167.8	0	0	0	110	F388 I389 R394 V395	F388-I392 HydrophobicContact CD1-CD1 3.8Å; F388-I392 HydrophobicContact CE1-CD1 3.27Å; F388-I392 HydrophobicContact CE1-CG1 4.32Å; F388-I392 HydrophobicContact CE2-CD1 4.2Å; F388-I392 HydrophobicContact CE2-CG1 4.49Å; F388-I392 HydrophobicContact CG-CD1 4.48Å; F388-I392 HydrophobicContact CZ-CD1 3.51Å; F388-I392 HydrophobicContact CZ-CG1 4.22Å; F388-I392 PolarHBondContact O-N 3.29Å; I389-I392 PolarHBondContact O-N 3.11Å; I392-R394 PolarHBondContact O-N 2.98Å; I392-R394 VanDerWaalsContact O-N 3.11Å; I392-V395 PolarHBondContact O-N 3.29Å
393	N	84.4	Confident	79.9	Confident	128 Å²	128	114.2 Å²	114.2	68%	0.684	57%	0.57	S	S	*	*	T	Hydrogen-bonded Turn	trans	-69.9	-5.6	-178.9	-71.2	-15.3	0	0	0	114.3	I389	I389-N393 PolarHBondContact O-N 3.05Å
394	R	76.4	Confident	80	Confident	216 Å²	216	113.8 Å²	113.8	82%	0.815	57%	0.572	S	S	*	*	T	Hydrogen-bonded Turn	trans	-96.2	-8.6	175.5	-77.7	-175.9	-174.6	-169	3.8	114	E390 S391 I392	E390-R394 WeakPolarHBondContact O-CG 3.47Å; E390-R394 PolarHBondContact O-N 3.29Å; S391-R394 PolarHBondContact O-N 3.38Å; I392-R394 PolarHBondContact O-N 2.98Å; I392-R394 VanDerWaalsContact O-N 3.11Å
395	V	66.7	Low	80.3	Confident	185 Å²	185	116.1 Å²	116.1	100%	1.121	58%	0.58	S	S	*	*			trans	-97.3	0	171.8	-177.8	0	0	0	0	108.1	I392	I392-V395 PolarHBondContact O-N 3.29Å

Retrieved 395 of 395 residues in 675.7 ms (Link to these results)

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