A0A5K4F184_SCHMA Loading...

Transmembrane protein

AlphaFold DB , UniProt , Accession A0A5K4F184, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 292 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	56.7	Low	58.8	Low	214 Å²	214	136.4 Å²	136.4	100%	1.054	65%	0.653	S	S	*	*				0	-53	0	-89.8	178.7	169.9	0	0	112.7	K3 N4 Q5	M1-K3 PolarHBondContact O-N 3.24Å; M1-N4 PolarHBondContact O-N 3.3Å; M1-N4 VanDerWaalsContact O-N 3.16Å; M1-Q5 PolarHBondContact O-N 3.47Å
2	L	53.7	Low	58.6	Low	135 Å²	135	138.1 Å²	138.1	71%	0.707	66%	0.655	S	S	*	*	H	α-helix	trans	-53.8	-42	179.4	-83.4	152.4	0	0	0	114.9	N4 Q5 E6	L2-N4 VanDerWaalsContact C-N 3.29Å; L2-N4 PolarHBondContact O-N 2.95Å; L2-Q5 PolarHBondContact O-N 3.33Å; L2-Q5 VanDerWaalsContact O-N 3.1Å; L2-E6 PolarHBondContact O-N 3.46Å; L2-E6 VanDerWaalsContact O-N 3.16Å
3	K	59.9	Low	57.9	Low	176 Å²	176	138.3 Å²	138.3	77%	0.765	66%	0.656	S	S	*	*	H	α-helix	trans	-64.5	-28.9	-179.6	-155.7	173.7	-176.1	179.4	0	114.1	M1 Y7	M1-K3 PolarHBondContact O-N 3.24Å; K3-Y7 PolarHBondContact O-N 3.49Å
4	N	62	Low	57.2	Low	119 Å²	119	139 Å²	139	64%	0.636	66%	0.655	S	S	*	*	H	α-helix	trans	-75.8	-32	175.1	-82.3	8.9	0	0	0	111.8	M1 L2 Y7 Q8	M1-N4 PolarHBondContact O-N 3.3Å; M1-N4 VanDerWaalsContact O-N 3.16Å; L2-N4 VanDerWaalsContact C-N 3.29Å; L2-N4 PolarHBondContact O-N 2.95Å; N4-Y7 PolarHBondContact O-N 2.94Å; N4-Q8 WeakPolarHBondContact O-CG 3.32Å; N4-Q8 PolarHBondContact O-N 3.33Å
5	Q	63.5	Low	56.6	Low	126 Å²	126	136.3 Å²	136.3	59%	0.589	65%	0.647	S	S	*	*	H	α-helix	trans	-69.3	-39.8	176.7	-70.4	-179.6	-36.5	0	0	111.4	M1 L2 Y7 Q8 A9	M1-Q5 PolarHBondContact O-N 3.47Å; L2-Q5 PolarHBondContact O-N 3.33Å; L2-Q5 VanDerWaalsContact O-N 3.1Å; Q5-Y7 VanDerWaalsContact C-N 3.32Å; Q5-Y7 PolarHBondContact O-N 2.99Å; Q5-Q8 PolarHBondContact O-N 3.1Å; Q5-A9 WeakPolarHBondContact O-CB 3.36Å; Q5-A9 PolarHBondContact O-N 3.26Å
6	E	56.8	Low	56.1	Low	134 Å²	134	136.5 Å²	136.5	63%	0.626	64%	0.644	S	S	*	*	H	α-helix	trans	-63.1	-38.4	173.2	-73.2	-176.2	165.3	0	0	112.3	L2 A9 K10	L2-E6 PolarHBondContact O-N 3.46Å; L2-E6 VanDerWaalsContact O-N 3.16Å; E6-A9 PolarHBondContact O-N 3.19Å; E6-K10 PolarHBondContact O-N 2.88Å
7	Y	59.7	Low	55.3	Low	159 Å²	159	136.1 Å²	136.1	62%	0.624	64%	0.642	S	S	*	*	H	α-helix	trans	-66.8	-45.1	178.3	-144.8	-87.2	0	0	0	111.7	K3 N4 Q5 A9 K10 E11	K3-Y7 PolarHBondContact O-N 3.49Å; N4-Y7 PolarHBondContact O-N 2.94Å; Q5-Y7 VanDerWaalsContact C-N 3.32Å; Q5-Y7 PolarHBondContact O-N 2.99Å; Y7-A9 VanDerWaalsContact C-N 3.3Å; Y7-A9 PolarHBondContact O-N 2.66Å; Y7-K10 PolarHBondContact O-N 3.08Å; Y7-E11 PolarHBondContact O-N 2.93Å
8	Q	60.8	Low	55	Low	126 Å²	126	131.6 Å²	131.6	59%	0.589	62%	0.624	S	S	*	*	H	α-helix	trans	-64.8	-32.8	175.6	-73.3	-175.7	-14.2	0	0	112.8	N4 Q5 K12	N4-Q8 WeakPolarHBondContact O-CG 3.32Å; N4-Q8 PolarHBondContact O-N 3.33Å; Q5-Q8 PolarHBondContact O-N 3.1Å; Q8-K12 WeakPolarHBondContact O-CG 3.35Å; Q8-K12 PolarHBondContact O-N 3.36Å; Q8-K12 VanDerWaalsContact O-N 3.1Å
9	A	65	Low	54.6	Low	52 Å²	52	128.4 Å²	128.4	43%	0.43	61%	0.614	S	S	.	*	H	α-helix	trans	-67.5	-39.4	174.2	0	0	0	0	0	111.8	Q5 E6 Y7 Q13	Q5-A9 WeakPolarHBondContact O-CB 3.36Å; Q5-A9 PolarHBondContact O-N 3.26Å; E6-A9 PolarHBondContact O-N 3.19Å; Y7-A9 VanDerWaalsContact C-N 3.3Å; Y7-A9 PolarHBondContact O-N 2.66Å; A9-Q13 PolarHBondContact O-N 3.27Å
10	K	58.6	Low	54.2	Low	148 Å²	148	126.9 Å²	126.9	64%	0.643	61%	0.61	S	S	*	*	H	α-helix	trans	-68	-41.1	175.9	-77	-174.1	178.3	-176.7	0	112.7	E6 Y7 Q13 F14	E6-K10 PolarHBondContact O-N 2.88Å; Y7-K10 PolarHBondContact O-N 3.08Å; K10-Q13 PolarHBondContact O-N 3.04Å; K10-F14 WeakPolarHBondContact O-CB 3.11Å; K10-F14 PolarHBondContact O-N 3.4Å
11	E	49.7	Very low	53.8	Low	111 Å²	111	125.2 Å²	125.2	52%	0.519	61%	0.605	S	S	.	*	H	α-helix	trans	-61.8	-46.3	174	-85.3	-178.3	159.5	0	0	111.6	Y7 Q13 F14 D15	Y7-E11 PolarHBondContact O-N 2.93Å; E11-Q13 VanDerWaalsContact C-N 3.29Å; E11-Q13 PolarHBondContact O-N 2.92Å; E11-F14 PolarHBondContact O-N 3.04Å; E11-F14 VanDerWaalsContact O-N 3.13Å; E11-D15 PolarHBondContact O-N 3.32Å
12	K	56.9	Low	53.5	Low	157 Å²	157	119.4 Å²	119.4	68%	0.683	58%	0.578	S	S	*	*	H	α-helix	trans	-62.2	-35	176.3	-76.8	-176	178.7	-177.4	0	113.2	Q8 K16	Q8-K12 WeakPolarHBondContact O-CG 3.35Å; Q8-K12 PolarHBondContact O-N 3.36Å; Q8-K12 VanDerWaalsContact O-N 3.1Å; K12-K16 VanDerWaalsContact O-CB 3.27Å; K12-K16 WeakPolarHBondContact O-CB 3.27Å; K12-K16 PolarHBondContact O-N 2.77Å
13	Q	48.9	Very low	53.1	Low	141 Å²	141	117.4 Å²	117.4	66%	0.659	57%	0.568	S	S	*	*	H	α-helix	trans	-70.1	-40.3	173.9	-82.8	-171	-28.5	0	0	112	A9 K10 E11 K16 H17	A9-Q13 PolarHBondContact O-N 3.27Å; K10-Q13 PolarHBondContact O-N 3.04Å; E11-Q13 VanDerWaalsContact C-N 3.29Å; E11-Q13 PolarHBondContact O-N 2.92Å; Q13-K16 PolarHBondContact O-N 2.98Å; Q13-H17 PolarHBondContact O-N 2.98Å
14	F	47.9	Very low	52.5	Low	148 Å²	148	110.5 Å²	110.5	65%	0.649	55%	0.547	S	S	*	.	H	α-helix	trans	-62.4	-51.3	176.3	-163.6	-96.2	0	0	0	110	K10 E11 K16 H17 T18	K10-F14 WeakPolarHBondContact O-CB 3.11Å; K10-F14 PolarHBondContact O-N 3.4Å; E11-F14 PolarHBondContact O-N 3.04Å; E11-F14 VanDerWaalsContact O-N 3.13Å; F14-K16 VanDerWaalsContact C-N 3.29Å; F14-K16 PolarHBondContact O-N 3.41Å; F14-H17 CarbonylContact O-C 3.58Å; F14-H17 WeakPolarHBondContact O-CA 3.36Å; F14-H17 WeakPolarHBondContact O-CB 3.13Å; F14-H17 PolarHBondContact O-N 3.45Å; F14-T18 PolarHBondContact O-N 2.95Å; F14-T18 PolarHBondContact O-OG1 3.26Å
15	D	48.5	Very low	52	Low	99 Å²	99	109.9 Å²	109.9	53%	0.529	54%	0.542	S	S	.	.	H	α-helix	trans	-58.7	-37.7	176.8	-73.6	-19.9	0	0	0	112.7	E11 H17 T18 T19	E11-D15 PolarHBondContact O-N 3.32Å; D15-H17 VanDerWaalsContact C-N 3.34Å; D15-T18 PolarHBondContact O-N 3.1Å; D15-T19 WeakPolarHBondContact O-CB 3.38Å; D15-T19 WeakPolarHBondContact O-CG2 3.38Å; D15-T19 PolarHBondContact O-N 3.37Å; D15-T19 PolarHBondContact O-OG1 3.17Å
16	K	48.7	Very low	51.3	Low	139 Å²	139	110.5 Å²	110.5	60%	0.604	55%	0.545	S	S	*	.	H	α-helix	trans	-68	-34.3	174.9	-163.2	174.1	-175.6	-178.5	0	112.2	K12 Q13 F14 T19 N20	K12-K16 VanDerWaalsContact O-CB 3.27Å; K12-K16 WeakPolarHBondContact O-CB 3.27Å; K12-K16 PolarHBondContact O-N 2.77Å; Q13-K16 PolarHBondContact O-N 2.98Å; F14-K16 VanDerWaalsContact C-N 3.29Å; F14-K16 PolarHBondContact O-N 3.41Å; K16-T19 VanDerWaalsContact CA-OG1 3.28Å; K16-T19 WeakPolarHBondContact CA-OG1 2.91Å; K16-T19 PolarHBondContact O-OG1 3.14Å; K16-N20 VanDerWaalsContact O-CB 3.28Å; K16-N20 WeakPolarHBondContact O-CB 3.34Å; K16-N20 PolarHBondContact O-N 2.9Å
17	H	43.5	Very low	51.3	Low	130 Å²	130	108.5 Å²	108.5	60%	0.602	54%	0.539	S	S	*	.	H	α-helix	trans	-72.8	-39.1	174.9	-122.7	-63.3	0	0	0	111.9	Q13 F14 D15 N21	Q13-H17 PolarHBondContact O-N 2.98Å; F14-H17 CarbonylContact O-C 3.58Å; F14-H17 WeakPolarHBondContact O-CA 3.36Å; F14-H17 WeakPolarHBondContact O-CB 3.13Å; F14-H17 PolarHBondContact O-N 3.45Å; D15-H17 VanDerWaalsContact C-N 3.34Å; H17-N21 VanDerWaalsContact O-CB 3.24Å; H17-N21 WeakPolarHBondContact O-CB 3.17Å; H17-N21 VanDerWaalsContact O-CG 3.3Å; H17-N21 PolarHBondContact O-N 2.71Å
18	T	49.3	Very low	51.1	Low	54 Å²	54	104.9 Å²	104.9	33%	0.331	53%	0.527	S	S	.	.	H	α-helix	trans	-69.3	-38.9	175.1	-5.8	0	0	0	0	111.7	F14 D15 N22	F14-T18 PolarHBondContact O-N 2.95Å; F14-T18 PolarHBondContact O-OG1 3.26Å; D15-T18 PolarHBondContact O-N 3.1Å; T18-N22 WeakPolarHBondContact O-CB 3.25Å; T18-N22 PolarHBondContact O-N 3.29Å; T18-N22 PolarHBondContact O-ND2 3.37Å
19	T	47.3	Very low	51.1	Low	71 Å²	71	100.5 Å²	100.5	44%	0.436	52%	0.516	S	S	.	.	H	α-helix	trans	-69.7	-45.9	176.1	44.7	0	0	0	0	111.7	D15 K16 N21 N22 D23	D15-T19 WeakPolarHBondContact O-CB 3.38Å; D15-T19 WeakPolarHBondContact O-CG2 3.38Å; D15-T19 PolarHBondContact O-N 3.37Å; D15-T19 PolarHBondContact O-OG1 3.17Å; K16-T19 VanDerWaalsContact CA-OG1 3.28Å; K16-T19 WeakPolarHBondContact CA-OG1 2.91Å; K16-T19 PolarHBondContact O-OG1 3.14Å; T19-N21 VanDerWaalsContact C-N 3.34Å; T19-N21 PolarHBondContact O-N 2.84Å; T19-N22 PolarHBondContact O-N 2.99Å; T19-D23 WeakPolarHBondContact O-CB 3.16Å; T19-D23 PolarHBondContact O-N 2.99Å
20	N	46.8	Very low	50.9	Low	99 Å²	99	100.5 Å²	100.5	53%	0.529	51%	0.511	S	S	.	.	H	α-helix	trans	-62.1	-39.6	174.6	-85.1	-1.5	0	0	0	112.8	K16 G24	K16-N20 VanDerWaalsContact O-CB 3.28Å; K16-N20 WeakPolarHBondContact O-CB 3.34Å; K16-N20 PolarHBondContact O-N 2.9Å; N20-G24 PolarHBondContact O-N 2.84Å
21	N	46.1	Very low	51.3	Low	92 Å²	92	97.9 Å²	97.9	49%	0.492	50%	0.504	S	S	.	.	H	α-helix	trans	-69.3	-40.2	175.7	-78.7	2.3	0	0	0	111.4	H17 T19 G24 I25	H17-N21 VanDerWaalsContact O-CB 3.24Å; H17-N21 WeakPolarHBondContact O-CB 3.17Å; H17-N21 VanDerWaalsContact O-CG 3.3Å; H17-N21 PolarHBondContact O-N 2.71Å; T19-N21 VanDerWaalsContact C-N 3.34Å; T19-N21 PolarHBondContact O-N 2.84Å; N21-G24 PolarHBondContact O-N 2.92Å; N21-I25 WeakPolarHBondContact O-CB 3.43Å; N21-I25 WeakPolarHBondContact O-CD1 3.33Å; N21-I25 WeakPolarHBondContact O-CG1 3.32Å; N21-I25 PolarHBondContact O-N 3.49Å
22	N	49	Very low	52.2	Low	92 Å²	92	96.4 Å²	96.4	49%	0.492	49%	0.494	S	S	.	.	H	α-helix	trans	-67.7	-39.8	177.2	-76.6	-11.8	0	0	0	111.6	T18 T19 I25 H26	T18-N22 WeakPolarHBondContact O-CB 3.25Å; T18-N22 PolarHBondContact O-N 3.29Å; T18-N22 PolarHBondContact O-ND2 3.37Å; T19-N22 PolarHBondContact O-N 2.99Å; N22-I25 PolarHBondContact O-N 2.73Å; N22-H26 WeakPolarHBondContact O-CB 3.26Å; N22-H26 PolarHBondContact O-N 2.91Å
23	D	47.1	Very low	53	Low	92 Å²	92	95.6 Å²	95.6	49%	0.492	49%	0.49	S	S	.	.	H	α-helix	trans	-65.2	-41.5	176.1	-69.6	-19	0	0	0	110.4	T19 N27	T19-D23 WeakPolarHBondContact O-CB 3.16Å; T19-D23 PolarHBondContact O-N 2.99Å; D23-N27 WeakPolarHBondContact O-CB 3.49Å; D23-N27 PolarHBondContact O-N 3.49Å; D23-N27 PolarHBondContact O-ND2 2.95Å; D23-N27 VanDerWaalsContact O-ND2 3.14Å
24	G	46.2	Very low	54.3	Low	32 Å²	32	93.7 Å²	93.7	33%	0.33	48%	0.481	S	S	.	.	H	α-helix	trans	-60.3	-51.9	172.4	0	0	0	0	0	112.8	N20 N21 H26 N27 E28	N20-G24 PolarHBondContact O-N 2.84Å; N21-G24 PolarHBondContact O-N 2.92Å; G24-H26 VanDerWaalsContact C-N 3.35Å; G24-H26 PolarHBondContact O-N 3.47Å; G24-N27 PolarHBondContact O-N 3.42Å; G24-E28 WeakPolarHBondContact O-CG 3.34Å; G24-E28 PolarHBondContact O-N 3.47Å
25	I	52	Low	55.8	Low	105 Å²	105	87 Å²	87	54%	0.538	45%	0.452	S	S	.	.	H	α-helix	trans	-63	-40.3	179.3	-68.4	165.1	0	0	0	111.4	N21 N22 G29	N21-I25 WeakPolarHBondContact O-CB 3.43Å; N21-I25 WeakPolarHBondContact O-CD1 3.33Å; N21-I25 WeakPolarHBondContact O-CG1 3.32Å; N21-I25 PolarHBondContact O-N 3.49Å; N22-I25 PolarHBondContact O-N 2.73Å; I25-G29 PolarHBondContact O-N 3.3Å; I25-G29 VanDerWaalsContact O-N 3.13Å
26	H	49.1	Very low	57.2	Low	139 Å²	139	84.4 Å²	84.4	64%	0.644	44%	0.435	S	S	*	.	H	α-helix	trans	-72.7	-33.8	-179.4	-155	-64.6	0	0	0	111.5	N22 G24 T30	N22-H26 WeakPolarHBondContact O-CB 3.26Å; N22-H26 PolarHBondContact O-N 2.91Å; G24-H26 VanDerWaalsContact C-N 3.35Å; G24-H26 PolarHBondContact O-N 3.47Å; H26-T30 WeakPolarHBondContact O-CB 3.01Å; H26-T30 PolarHBondContact O-N 3.12Å; H26-T30 PolarHBondContact O-OG1 3.02Å
27	N	55.4	Low	58.9	Low	93 Å²	93	81.3 Å²	81.3	50%	0.497	42%	0.424	S	S	.	.	H	α-helix	trans	-68.7	-47.1	173.1	-72.9	-19.6	0	0	0	111.2	D23 G24 G29 T30 D31	D23-N27 WeakPolarHBondContact O-CB 3.49Å; D23-N27 PolarHBondContact O-N 3.49Å; D23-N27 PolarHBondContact O-ND2 2.95Å; D23-N27 VanDerWaalsContact O-ND2 3.14Å; G24-N27 PolarHBondContact O-N 3.42Å; N27-G29 VanDerWaalsContact C-N 3.32Å; N27-G29 PolarHBondContact O-N 2.9Å; N27-T30 CarbonylContact O-C 3.3Å; N27-T30 WeakPolarHBondContact O-CA 3.44Å; N27-T30 WeakPolarHBondContact O-CB 3.37Å; N27-T30 PolarHBondContact O-N 3.45Å; N27-D31 PolarHBondContact O-N 3.33Å
28	E	56.7	Low	60.8	Low	82 Å²	82	79.5 Å²	79.5	38%	0.383	41%	0.414	S	S	.	.	H	α-helix	trans	-58.6	-42.6	177.4	-74.8	179.8	-164.4	0	0	112.5	G24 T30 R32	G24-E28 WeakPolarHBondContact O-CG 3.34Å; G24-E28 PolarHBondContact O-N 3.47Å; E28-T30 VanDerWaalsContact C-N 3.26Å; E28-T30 PolarHBondContact O-N 3.35Å; E28-R32 WeakPolarHBondContact O-CB 3.27Å; E28-R32 VanDerWaalsContact O-CG 3.27Å; E28-R32 WeakPolarHBondContact O-CG 3.39Å; E28-R32 PolarHBondContact O-N 2.95Å; E28-R32 VanDerWaalsContact O-N 3.15Å; E28-R32 PolarHBondContact O-NE 2.89Å; E28-R32 VanDerWaalsContact O-NE 3.17Å; E28-R32 IonicContact OE2-CZ 2.67Å; E28-R32 IonicContact OE2-NH1 3.38Å; E28-R32 PolarHBondContact OE2-NH1 3.11Å; E28-R32 IonicContact OE2-NH2 3.54Å
29	G	60.1	Low	62.7	Low	35 Å²	35	77.1 Å²	77.1	36%	0.361	40%	0.4	S	S	.	.	H	α-helix	trans	-61	-37.4	174.7	0	0	0	0	0	112.6	I25 N27 K33	I25-G29 PolarHBondContact O-N 3.3Å; I25-G29 VanDerWaalsContact O-N 3.13Å; N27-G29 VanDerWaalsContact C-N 3.32Å; N27-G29 PolarHBondContact O-N 2.9Å; G29-K33 PolarHBondContact O-N 3.39Å
30	T	61.3	Low	64.6	Low	52 Å²	52	77 Å²	77	32%	0.319	40%	0.396	S	S	.	.	H	α-helix	trans	-73.6	-43.7	-179	-57.7	0	0	0	0	111.5	H26 N27 E28 K33 H34	H26-T30 WeakPolarHBondContact O-CB 3.01Å; H26-T30 PolarHBondContact O-N 3.12Å; H26-T30 PolarHBondContact O-OG1 3.02Å; N27-T30 CarbonylContact O-C 3.3Å; N27-T30 WeakPolarHBondContact O-CA 3.44Å; N27-T30 WeakPolarHBondContact O-CB 3.37Å; N27-T30 PolarHBondContact O-N 3.45Å; E28-T30 VanDerWaalsContact C-N 3.26Å; E28-T30 PolarHBondContact O-N 3.35Å; T30-K33 WeakPolarHBondContact O-CB 3.23Å; T30-K33 PolarHBondContact O-N 3Å; T30-H34 VanDerWaalsContact CG2-CE1 3.46Å; T30-H34 WeakPolarHBondContact CG2-CE1 3.38Å; T30-H34 PolarHBondContact O-N 3.39Å; T30-H34 VanDerWaalsContact O-N 3.09Å; T30-H34 PolarHBondContact O-ND1 3.47Å
31	D	66.2	Low	66.7	Low	92 Å²	92	76.9 Å²	76.9	49%	0.492	39%	0.394	S	S	.	.	H	α-helix	trans	-66.1	-41.6	-179.8	-70.1	-23	0	0	0	111.7	N27 K33 H34 F35	N27-D31 PolarHBondContact O-N 3.33Å; D31-K33 VanDerWaalsContact C-N 3.34Å; D31-K33 PolarHBondContact O-N 3.47Å; D31-H34 PolarHBondContact O-N 3.48Å; D31-F35 PolarHBondContact O-N 3.45Å
32	R	69.9	Low	68.9	Low	81 Å²	81	73.7 Å²	73.7	31%	0.306	38%	0.378	S	S	.	.	H	α-helix	trans	-57.7	-46.3	172.8	-73.9	-176.7	-71.3	-123.9	-0.9	111.6	E28 H34 F35 Y36	E28-R32 WeakPolarHBondContact O-CB 3.27Å; E28-R32 VanDerWaalsContact O-CG 3.27Å; E28-R32 WeakPolarHBondContact O-CG 3.39Å; E28-R32 PolarHBondContact O-N 2.95Å; E28-R32 VanDerWaalsContact O-N 3.15Å; E28-R32 PolarHBondContact O-NE 2.89Å; E28-R32 VanDerWaalsContact O-NE 3.17Å; E28-R32 IonicContact OE2-CZ 2.67Å; E28-R32 IonicContact OE2-NH1 3.38Å; E28-R32 PolarHBondContact OE2-NH1 3.11Å; E28-R32 IonicContact OE2-NH2 3.54Å; R32-H34 VanDerWaalsContact C-N 3.31Å; R32-H34 PolarHBondContact O-N 3.5Å; R32-F35 WeakPolarHBondContact O-CB 3.44Å; R32-F35 PolarHBondContact O-N 2.9Å; R32-Y36 HydrophobicContact CB-CE2 4.13Å; R32-Y36 WeakPolarHBondContact O-CD2 3.32Å; R32-Y36 WeakPolarHBondContact O-CE2 3.44Å; R32-Y36 PolarHBondContact O-N 3.27Å
33	K	73.4	Confident	71	Confident	139 Å²	139	69.3 Å²	69.3	60%	0.604	36%	0.355	S	S	*	.	H	α-helix	trans	-58.6	-43	177.5	-171.2	-178.8	177.8	-176.6	0	111.8	G29 T30 D31 Y36 I37	G29-K33 PolarHBondContact O-N 3.39Å; T30-K33 WeakPolarHBondContact O-CB 3.23Å; T30-K33 PolarHBondContact O-N 3Å; D31-K33 VanDerWaalsContact C-N 3.34Å; D31-K33 PolarHBondContact O-N 3.47Å; K33-Y36 PolarHBondContact O-N 3.4Å; K33-I37 HydrophobicContact CG-CD1 3.94Å; K33-I37 WeakPolarHBondContact O-CD1 3.42Å; K33-I37 VanDerWaalsContact O-CG1 3.23Å; K33-I37 WeakPolarHBondContact O-CG1 3.37Å; K33-I37 PolarHBondContact O-N 2.79Å
34	H	75	Confident	73.2	Confident	101 Å²	101	69.4 Å²	69.4	47%	0.468	36%	0.355	S	S	.	.	H	α-helix	trans	-64.4	-39.3	177.2	-73.2	96.9	0	0	0	112.4	T30 D31 R32 I37 K38	T30-H34 VanDerWaalsContact CG2-CE1 3.46Å; T30-H34 WeakPolarHBondContact CG2-CE1 3.38Å; T30-H34 PolarHBondContact O-N 3.39Å; T30-H34 VanDerWaalsContact O-N 3.09Å; T30-H34 PolarHBondContact O-ND1 3.47Å; D31-H34 PolarHBondContact O-N 3.48Å; R32-H34 VanDerWaalsContact C-N 3.31Å; R32-H34 PolarHBondContact O-N 3.5Å; H34-I37 PolarHBondContact O-N 3.23Å; H34-K38 WeakPolarHBondContact O-CG 3.33Å; H34-K38 PolarHBondContact O-N 2.69Å
35	F	80.2	Confident	75.5	Confident	8 Å²	8	70.9 Å²	70.9	4%	0.035	36%	0.36	C	S	.	.	H	α-helix	trans	-60.1	-50.3	174.7	174.9	-106.4	0	0	0	112.1	D31 R32 I37 K38 V39 L210 V218	D31-F35 PolarHBondContact O-N 3.45Å; R32-F35 WeakPolarHBondContact O-CB 3.44Å; R32-F35 PolarHBondContact O-N 2.9Å; F35-I37 VanDerWaalsContact C-N 3.3Å; F35-I37 PolarHBondContact O-N 2.81Å; F35-K38 WeakPolarHBondContact O-CB 3.43Å; F35-K38 PolarHBondContact O-N 3.01Å; F35-K38 VanDerWaalsContact O-N 3.1Å; F35-V39 HydrophobicContact CD1-CG2 4.47Å; F35-V39 HydrophobicContact CD2-CG2 4.41Å; F35-V39 HydrophobicContact CE1-CG2 4.04Å; F35-V39 HydrophobicContact CE2-CG2 3.99Å; F35-V39 HydrophobicContact CZ-CG2 3.77Å; F35-V39 PolarHBondContact O-N 2.53Å; F35-L210 HydrophobicContact CE1-CB 4.41Å; F35-L210 HydrophobicContact CE1-CD2 3.66Å; F35-L210 HydrophobicContact CZ-CD2 3.75Å; F35-V218 HydrophobicContact CD1-CG1 4.4Å; F35-V218 HydrophobicContact CD2-CG1 4.44Å; F35-V218 HydrophobicContact CE1-CB 4.34Å; F35-V218 HydrophobicContact CE1-CG1 3.74Å; F35-V218 HydrophobicContact CE2-CG1 3.78Å; F35-V218 HydrophobicContact CZ-CB 4.42Å; F35-V218 HydrophobicContact CZ-CG1 3.4Å
36	Y	78.8	Confident	77.6	Confident	44 Å²	44	66.1 Å²	66.1	17%	0.173	34%	0.336	C	S	.	.	H	α-helix	trans	-60.2	-40.6	177.4	-64.2	-65.2	0	0	0	112.7	R32 K33 K38 V39 L40 F143 L210 Q211	R32-Y36 HydrophobicContact CB-CE2 4.13Å; R32-Y36 WeakPolarHBondContact O-CD2 3.32Å; R32-Y36 WeakPolarHBondContact O-CE2 3.44Å; R32-Y36 PolarHBondContact O-N 3.27Å; K33-Y36 PolarHBondContact O-N 3.4Å; Y36-K38 VanDerWaalsContact C-N 3.3Å; Y36-K38 PolarHBondContact O-N 3.01Å; Y36-V39 PolarHBondContact O-N 3.48Å; Y36-L40 VanDerWaalsContact O-CB 3.27Å; Y36-L40 WeakPolarHBondContact O-CB 3.18Å; Y36-L40 PolarHBondContact O-N 3.22Å; Y36-F143 HydrophobicContact CD1-CZ 4.23Å; Y36-L210 HydrophobicContact CE1-CB 4.34Å; Y36-Q211 HydrophobicContact CE1-CG 4.28Å; Y36-Q211 WeakPolarHBondContact OH-CA 3.45Å; Y36-Q211 WeakPolarHBondContact OH-CG 3.33Å
37	I	82.9	Confident	79.8	Confident	74 Å²	74	60.3 Å²	60.3	38%	0.379	31%	0.31	S	S	.	.	H	α-helix	trans	-61.2	-42.3	177.4	-70.7	167.5	0	0	0	110.1	K33 H34 F35 L40 I41	K33-I37 HydrophobicContact CG-CD1 3.94Å; K33-I37 WeakPolarHBondContact O-CD1 3.42Å; K33-I37 VanDerWaalsContact O-CG1 3.23Å; K33-I37 WeakPolarHBondContact O-CG1 3.37Å; K33-I37 PolarHBondContact O-N 2.79Å; H34-I37 PolarHBondContact O-N 3.23Å; F35-I37 VanDerWaalsContact C-N 3.3Å; F35-I37 PolarHBondContact O-N 2.81Å; I37-L40 PolarHBondContact O-N 2.95Å; I37-I41 HydrophobicContact CG2-CD1 3.65Å; I37-I41 HydrophobicContact CG2-CG1 4.33Å; I37-I41 WeakPolarHBondContact O-CB 3.2Å; I37-I41 WeakPolarHBondContact O-CG1 3.42Å; I37-I41 PolarHBondContact O-N 3.21Å
38	K	85	Confident	81.7	Confident	92 Å²	92	62.1 Å²	62.1	40%	0.4	31%	0.314	S	S	.	.	H	α-helix	trans	-62.9	-49	176	-74.5	-178.9	178.7	-173.7	0	112.2	H34 F35 Y36 L40 I41 V42 V220 Y223	H34-K38 WeakPolarHBondContact O-CG 3.33Å; H34-K38 PolarHBondContact O-N 2.69Å; F35-K38 WeakPolarHBondContact O-CB 3.43Å; F35-K38 PolarHBondContact O-N 3.01Å; F35-K38 VanDerWaalsContact O-N 3.1Å; Y36-K38 VanDerWaalsContact C-N 3.3Å; Y36-K38 PolarHBondContact O-N 3.01Å; K38-L40 VanDerWaalsContact C-N 3.28Å; K38-L40 PolarHBondContact O-N 3.14Å; K38-I41 PolarHBondContact O-N 3.15Å; K38-V42 WeakPolarHBondContact O-CG2 3.45Å; K38-V42 PolarHBondContact O-N 3.32Å; K38-V220 HydrophobicContact CD-CG1 3.83Å; K38-Y223 HydrophobicContact CB-CG 4.44Å
39	V	87.9	Confident	83.6	Confident	4 Å²	4	59.9 Å²	59.9	2%	0.024	30%	0.304	C	S	.	.	H	α-helix	trans	-56.6	-45.4	176.7	173.9	0	0	0	0	110.5	F35 Y36 V42 F43 L210	F35-V39 HydrophobicContact CD1-CG2 4.47Å; F35-V39 HydrophobicContact CD2-CG2 4.41Å; F35-V39 HydrophobicContact CE1-CG2 4.04Å; F35-V39 HydrophobicContact CE2-CG2 3.99Å; F35-V39 HydrophobicContact CZ-CG2 3.77Å; F35-V39 PolarHBondContact O-N 2.53Å; Y36-V39 PolarHBondContact O-N 3.48Å; V39-V42 PolarHBondContact O-N 3.11Å; V39-F43 VanDerWaalsContact O-CB 3.27Å; V39-F43 WeakPolarHBondContact O-CB 3.49Å; V39-F43 PolarHBondContact O-N 3.07Å; V39-L210 HydrophobicContact CG1-CD1 4.23Å; V39-L210 HydrophobicContact CG1-CD2 4.31Å; V39-L210 HydrophobicContact CG2-CD2 4.04Å
40	L	87.4	Confident	85.3	Confident	68 Å²	68	58.2 Å²	58.2	36%	0.356	29%	0.287	S	S	.	.	H	α-helix	trans	-66.2	-41.8	-179.6	-173.7	65.4	0	0	0	112.3	Y36 I37 K38 F43 L44 M140	Y36-L40 VanDerWaalsContact O-CB 3.27Å; Y36-L40 WeakPolarHBondContact O-CB 3.18Å; Y36-L40 PolarHBondContact O-N 3.22Å; I37-L40 PolarHBondContact O-N 2.95Å; K38-L40 VanDerWaalsContact C-N 3.28Å; K38-L40 PolarHBondContact O-N 3.14Å; L40-F43 HydrophobicContact CD1-CD1 4.25Å; L40-F43 PolarHBondContact O-N 3.5Å; L40-L44 HydrophobicContact CD1-CG 4.47Å; L40-L44 HydrophobicContact CG-CD1 4.17Å; L40-L44 HydrophobicContact CG-CG 4.45Å; L40-L44 WeakPolarHBondContact O-CB 3.47Å; L40-L44 WeakPolarHBondContact O-CG 3.21Å; L40-L44 PolarHBondContact O-N 3.32Å; L40-M140 HydrophobicContact CD1-CE 4.12Å
41	I	91	Very high	86.7	Confident	97 Å²	97	59.9 Å²	59.9	50%	0.497	29%	0.294	S	S	.	.	H	α-helix	trans	-61.7	-45	176.6	-72.9	166.8	0	0	0	110.8	I37 K38 L44 S45	I37-I41 HydrophobicContact CG2-CD1 3.65Å; I37-I41 HydrophobicContact CG2-CG1 4.33Å; I37-I41 WeakPolarHBondContact O-CB 3.2Å; I37-I41 WeakPolarHBondContact O-CG1 3.42Å; I37-I41 PolarHBondContact O-N 3.21Å; K38-I41 PolarHBondContact O-N 3.15Å; I41-L44 PolarHBondContact O-N 3.42Å; I41-S45 PolarHBondContact O-N 3.35Å; I41-S45 PolarHBondContact O-OG 3.3Å
42	V	92	Very high	88.1	Confident	25 Å²	25	59.6 Å²	59.6	15%	0.152	29%	0.292	C	S	.	.	H	α-helix	trans	-65.5	-46.3	178	176.5	0	0	0	0	110.4	K38 V39 L44 S45 Q46 L105 Y223 S227	K38-V42 WeakPolarHBondContact O-CG2 3.45Å; K38-V42 PolarHBondContact O-N 3.32Å; V39-V42 PolarHBondContact O-N 3.11Å; V42-L44 VanDerWaalsContact C-N 3.35Å; V42-L44 PolarHBondContact O-N 2.91Å; V42-S45 CarbonylContact O-C 3.54Å; V42-S45 WeakPolarHBondContact O-CA 3.28Å; V42-S45 VanDerWaalsContact O-CB 3.27Å; V42-S45 WeakPolarHBondContact O-CB 3.49Å; V42-S45 PolarHBondContact O-N 3.41Å; V42-Q46 WeakPolarHBondContact O-CG 3.3Å; V42-Q46 PolarHBondContact O-N 3Å; V42-L105 HydrophobicContact CG1-CD2 3.35Å; V42-Y223 HydrophobicContact CG2-CD2 3.68Å; V42-Y223 HydrophobicContact CG2-CE2 3.66Å; V42-S227 VanDerWaalsContact CG1-OG 3.24Å; V42-S227 WeakPolarHBondContact CG1-OG 3.43Å
43	F	92.8	Very high	89.2	Confident	1 Å²	1	56.4 Å²	56.4	0%	0.004	28%	0.281	C	S	.	.	H	α-helix	trans	-56.6	-46.4	175.6	169.2	-103.3	0	0	0	112.2	V39 L40 S45 Q46 V47 L136 M140 M230 F231 I234	V39-F43 VanDerWaalsContact O-CB 3.27Å; V39-F43 WeakPolarHBondContact O-CB 3.49Å; V39-F43 PolarHBondContact O-N 3.07Å; L40-F43 HydrophobicContact CD1-CD1 4.25Å; L40-F43 PolarHBondContact O-N 3.5Å; F43-S45 VanDerWaalsContact C-N 3.26Å; F43-S45 PolarHBondContact O-N 3.2Å; F43-Q46 WeakPolarHBondContact O-CA 3.31Å; F43-Q46 WeakPolarHBondContact O-CB 3.44Å; F43-Q46 PolarHBondContact O-N 3.36Å; F43-V47 HydrophobicContact CD1-CG2 4.41Å; F43-V47 HydrophobicContact CD2-CG2 4.37Å; F43-V47 HydrophobicContact CE1-CG2 3.81Å; F43-V47 HydrophobicContact CE2-CG2 3.73Å; F43-V47 HydrophobicContact CZ-CG2 3.41Å; F43-V47 VanDerWaalsContact CZ-CG2 3.41Å; F43-V47 WeakPolarHBondContact O-CG2 3.47Å; F43-V47 PolarHBondContact O-N 2.7Å; F43-L136 HydrophobicContact CE1-CD2 4.46Å; F43-L136 HydrophobicContact CZ-CD2 4.01Å; F43-M140 HydrophobicContact CE1-CE 4.12Å; F43-M230 HydrophobicContact CB-SD 4.26Å; F43-M230 HydrophobicContact CD1-SD 3.99Å; F43-M230 HydrophobicContact CD2-CB 4.34Å; F43-M230 HydrophobicContact CD2-CG 3.81Å; F43-M230 HydrophobicContact CD2-SD 3.95Å; F43-M230 HydrophobicContact CE1-SD 4.39Å; F43-M230 HydrophobicContact CE2-CG 3.97Å; F43-M230 HydrophobicContact CE2-SD 4.36Å; F43-M230 HydrophobicContact CG-CG 4.25Å; F43-M230 HydrophobicContact CG-SD 3.76Å; F43-F231 HydrophobicContact CD2-CB 4.4Å; F43-F231 HydrophobicContact CE2-CD2 4.35Å; F43-I234 HydrophobicContact CE1-CD1 4.17Å; F43-I234 HydrophobicContact CE2-CD1 3.51Å; F43-I234 HydrophobicContact CZ-CD1 3.26Å
44	L	93.6	Very high	90	Very high	94 Å²	94	51.2 Å²	51.2	49%	0.492	26%	0.259	S	S	.	.	H	α-helix	trans	-61.3	-35.9	175.9	-73.1	172.5	0	0	0	112	L40 I41 V42 Q46 V47 F48	L40-L44 HydrophobicContact CD1-CG 4.47Å; L40-L44 HydrophobicContact CG-CD1 4.17Å; L40-L44 HydrophobicContact CG-CG 4.45Å; L40-L44 WeakPolarHBondContact O-CB 3.47Å; L40-L44 WeakPolarHBondContact O-CG 3.21Å; L40-L44 PolarHBondContact O-N 3.32Å; I41-L44 PolarHBondContact O-N 3.42Å; V42-L44 VanDerWaalsContact C-N 3.35Å; V42-L44 PolarHBondContact O-N 2.91Å; L44-Q46 VanDerWaalsContact C-N 3.34Å; L44-V47 PolarHBondContact O-N 2.88Å; L44-F48 PolarHBondContact O-N 3.3Å
45	S	95	Very high	90.7	Very high	63 Å²	63	53.1 Å²	53.1	44%	0.441	26%	0.263	S	S	.	.	H	α-helix	trans	-65.2	-38.4	173.5	-54	0	0	0	0	111.5	I41 V42 F43 F48 I49	I41-S45 PolarHBondContact O-N 3.35Å; I41-S45 PolarHBondContact O-OG 3.3Å; V42-S45 CarbonylContact O-C 3.54Å; V42-S45 WeakPolarHBondContact O-CA 3.28Å; V42-S45 VanDerWaalsContact O-CB 3.27Å; V42-S45 WeakPolarHBondContact O-CB 3.49Å; V42-S45 PolarHBondContact O-N 3.41Å; F43-S45 VanDerWaalsContact C-N 3.26Å; F43-S45 PolarHBondContact O-N 3.2Å; S45-F48 WeakPolarHBondContact O-CB 3.46Å; S45-F48 PolarHBondContact O-N 2.91Å; S45-I49 WeakPolarHBondContact O-CG1 3.44Å; S45-I49 PolarHBondContact O-N 2.62Å
46	Q	96.2	Very high	91.2	Very high	4 Å²	4	55.4 Å²	55.4	2%	0.019	28%	0.277	C	S	.	.	H	α-helix	trans	-67	-40.5	174.9	-62	176.1	-67.4	0	0	112	V42 F43 L44 F48 I49 L50 L105 T109 S227 F231	V42-Q46 WeakPolarHBondContact O-CG 3.3Å; V42-Q46 PolarHBondContact O-N 3Å; F43-Q46 WeakPolarHBondContact O-CA 3.31Å; F43-Q46 WeakPolarHBondContact O-CB 3.44Å; F43-Q46 PolarHBondContact O-N 3.36Å; L44-Q46 VanDerWaalsContact C-N 3.34Å; Q46-F48 VanDerWaalsContact C-N 3.29Å; Q46-F48 PolarHBondContact O-N 2.96Å; Q46-I49 PolarHBondContact O-N 3.37Å; Q46-L50 WeakPolarHBondContact O-CB 3.42Å; Q46-L50 PolarHBondContact O-N 3.3Å; Q46-L105 VanDerWaalsContact NE2-CD1 3.34Å; Q46-T109 HydrophobicContact CB-CG2 3.82Å; Q46-T109 HydrophobicContact CG-CG2 4.21Å; Q46-T109 WeakPolarHBondContact CG-OG1 3.43Å; Q46-T109 PolarHBondContact NE2-OG1 3.43Å; Q46-S227 PolarHBondContact OE1-O 3.04Å; Q46-F231 HydrophobicContact CB-CD2 3.56Å; Q46-F231 HydrophobicContact CB-CE2 3.7Å; Q46-F231 HydrophobicContact CB-CG 4.13Å; Q46-F231 HydrophobicContact CB-CZ 4.37Å
47	V	94.9	Very high	91.5	Very high	18 Å²	18	54 Å²	54	11%	0.109	27%	0.272	C	S	.	.	H	α-helix	trans	-62.7	-37	173.5	174	0	0	0	0	111.2	F43 L44 L50 N51 F132	F43-V47 HydrophobicContact CD1-CG2 4.41Å; F43-V47 HydrophobicContact CD2-CG2 4.37Å; F43-V47 HydrophobicContact CE1-CG2 3.81Å; F43-V47 HydrophobicContact CE2-CG2 3.73Å; F43-V47 HydrophobicContact CZ-CG2 3.41Å; F43-V47 VanDerWaalsContact CZ-CG2 3.41Å; F43-V47 WeakPolarHBondContact O-CG2 3.47Å; F43-V47 PolarHBondContact O-N 2.7Å; L44-V47 PolarHBondContact O-N 2.88Å; V47-L50 WeakPolarHBondContact O-CB 3.32Å; V47-L50 PolarHBondContact O-N 2.93Å; V47-N51 PolarHBondContact O-N 3.43Å; V47-N51 PolarHBondContact O-ND2 3.1Å; V47-F132 HydrophobicContact CG1-CE1 4.05Å; V47-F132 HydrophobicContact CG1-CZ 4.04Å; V47-F132 HydrophobicContact CG2-CZ 4.34Å
48	F	95.7	Very high	91.5	Very high	130 Å²	130	52.8 Å²	52.8	57%	0.57	26%	0.263	S	S	*	.	H	α-helix	trans	-63	-45.9	173.8	177.4	-102.7	0	0	0	112	L44 S45 Q46 L50 N51 L52	L44-F48 PolarHBondContact O-N 3.3Å; S45-F48 WeakPolarHBondContact O-CB 3.46Å; S45-F48 PolarHBondContact O-N 2.91Å; Q46-F48 VanDerWaalsContact C-N 3.29Å; Q46-F48 PolarHBondContact O-N 2.96Å; F48-L50 VanDerWaalsContact C-N 3.32Å; F48-L50 PolarHBondContact O-N 3.19Å; F48-N51 PolarHBondContact O-N 3.38Å; F48-N51 VanDerWaalsContact O-N 3.17Å; F48-L52 HydrophobicContact CD1-CD1 4.09Å; F48-L52 HydrophobicContact CE1-CD1 3.52Å; F48-L52 HydrophobicContact CE1-CG 4.13Å; F48-L52 HydrophobicContact CZ-CD1 3.95Å; F48-L52 HydrophobicContact CZ-CD2 4.28Å; F48-L52 HydrophobicContact CZ-CG 4.19Å; F48-L52 PolarHBondContact O-N 3.35Å; F48-L52 VanDerWaalsContact O-N 3.08Å
49	I	96.2	Very high	91.5	Very high	36 Å²	36	56.2 Å²	56.2	19%	0.185	28%	0.275	C	S	.	.	H	α-helix	trans	-59.6	-44.1	175	-66.4	167	0	0	0	110.7	S45 Q46 N51 L52 V53 T109 I110	S45-I49 WeakPolarHBondContact O-CG1 3.44Å; S45-I49 PolarHBondContact O-N 2.62Å; Q46-I49 PolarHBondContact O-N 3.37Å; I49-N51 VanDerWaalsContact C-N 3.29Å; I49-N51 PolarHBondContact O-N 3.23Å; I49-L52 WeakPolarHBondContact O-CB 3.39Å; I49-L52 PolarHBondContact O-N 3.36Å; I49-L52 VanDerWaalsContact O-N 3.1Å; I49-V53 HydrophobicContact CG2-CG2 4.41Å; I49-V53 WeakPolarHBondContact O-CG2 3.32Å; I49-V53 PolarHBondContact O-N 3.03Å; I49-T109 HydrophobicContact CB-CG2 3.75Å; I49-T109 HydrophobicContact CD1-CG2 4.15Å; I49-T109 HydrophobicContact CG2-CG2 3.67Å; I49-I110 HydrophobicContact CG2-CG1 3.67Å
50	L	95.2	Very high	91.5	Very high	0 Å²	0	60 Å²	60	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-54.6	-45.8	175.3	171.9	66	0	0	0	111.7	Q46 V47 F48 L52 V53 F54 S113 F132 F231 L235	Q46-L50 WeakPolarHBondContact O-CB 3.42Å; Q46-L50 PolarHBondContact O-N 3.3Å; V47-L50 WeakPolarHBondContact O-CB 3.32Å; V47-L50 PolarHBondContact O-N 2.93Å; F48-L50 VanDerWaalsContact C-N 3.32Å; F48-L50 PolarHBondContact O-N 3.19Å; L50-L52 VanDerWaalsContact C-N 3.34Å; L50-L52 PolarHBondContact O-N 2.91Å; L50-V53 PolarHBondContact O-N 3.17Å; L50-F54 HydrophobicContact CD1-CD2 3.65Å; L50-F54 HydrophobicContact CD1-CE2 3.5Å; L50-F54 HydrophobicContact CD2-CE2 4.35Å; L50-F54 HydrophobicContact CG-CD2 3.81Å; L50-F54 HydrophobicContact CG-CE2 3.86Å; L50-F54 WeakPolarHBondContact O-CD2 3.49Å; L50-F54 PolarHBondContact O-N 3.45Å; L50-S113 WeakPolarHBondContact CD1-OG 3.39Å; L50-F132 HydrophobicContact CD2-CD2 4.28Å; L50-F132 HydrophobicContact CD2-CE1 4.23Å; L50-F132 HydrophobicContact CD2-CE2 3.48Å; L50-F132 VanDerWaalsContact CD2-CE2 3.48Å; L50-F132 HydrophobicContact CD2-CZ 3.46Å; L50-F132 VanDerWaalsContact CD2-CZ 3.46Å; L50-F231 HydrophobicContact CB-CE2 4.31Å; L50-F231 HydrophobicContact CB-CZ 4.36Å; L50-F231 HydrophobicContact CD2-CE2 4.45Å; L50-L235 HydrophobicContact CD1-CD1 4.14Å; L50-L235 HydrophobicContact CD1-CD2 3.89Å; L50-L235 HydrophobicContact CD2-CD1 4.33Å; L50-L235 HydrophobicContact CD2-CD2 3.53Å; L50-L235 HydrophobicContact CD2-CG 4.15Å; L50-L235 HydrophobicContact CG-CD2 4.35Å
51	N	92.6	Very high	91	Very high	86 Å²	86	59.8 Å²	59.8	46%	0.46	30%	0.297	S	S	.	.	H	α-helix	trans	-63	-38.8	177.5	-81.9	-87.2	0	0	0	112.2	V47 F48 I49 V53 F54 Y55	V47-N51 PolarHBondContact O-N 3.43Å; V47-N51 PolarHBondContact O-ND2 3.1Å; F48-N51 PolarHBondContact O-N 3.38Å; F48-N51 VanDerWaalsContact O-N 3.17Å; I49-N51 VanDerWaalsContact C-N 3.29Å; I49-N51 PolarHBondContact O-N 3.23Å; N51-V53 VanDerWaalsContact C-N 3.34Å; N51-F54 PolarHBondContact O-N 3.33Å; N51-Y55 WeakPolarHBondContact O-CB 3.06Å; N51-Y55 PolarHBondContact O-N 3.03Å
52	L	94.5	Very high	90.8	Very high	87 Å²	87	60 Å²	60	46%	0.455	30%	0.302	S	S	.	.	H	α-helix	trans	-64.2	-38.8	174.1	-68	178.1	0	0	0	112.2	F48 I49 L50 Y55 T56	F48-L52 HydrophobicContact CD1-CD1 4.09Å; F48-L52 HydrophobicContact CE1-CD1 3.52Å; F48-L52 HydrophobicContact CE1-CG 4.13Å; F48-L52 HydrophobicContact CZ-CD1 3.95Å; F48-L52 HydrophobicContact CZ-CD2 4.28Å; F48-L52 HydrophobicContact CZ-CG 4.19Å; F48-L52 PolarHBondContact O-N 3.35Å; F48-L52 VanDerWaalsContact O-N 3.08Å; I49-L52 WeakPolarHBondContact O-CB 3.39Å; I49-L52 PolarHBondContact O-N 3.36Å; I49-L52 VanDerWaalsContact O-N 3.1Å; L50-L52 VanDerWaalsContact C-N 3.34Å; L50-L52 PolarHBondContact O-N 2.91Å; L52-Y55 PolarHBondContact O-N 2.87Å; L52-T56 WeakPolarHBondContact O-CB 3.32Å; L52-T56 PolarHBondContact O-N 3.42Å; L52-T56 PolarHBondContact O-OG1 3.06Å
53	V	93.2	Very high	90.3	Very high	13 Å²	13	61.4 Å²	61.4	8%	0.079	31%	0.309	C	S	.	.	H	α-helix	trans	-65.1	-50.1	174.8	176.9	0	0	0	0	109.8	I49 L50 N51 Y55 T56 F57 V117	I49-V53 HydrophobicContact CG2-CG2 4.41Å; I49-V53 WeakPolarHBondContact O-CG2 3.32Å; I49-V53 PolarHBondContact O-N 3.03Å; L50-V53 PolarHBondContact O-N 3.17Å; N51-V53 VanDerWaalsContact C-N 3.34Å; V53-Y55 VanDerWaalsContact C-N 3.3Å; V53-Y55 PolarHBondContact O-N 3.23Å; V53-T56 PolarHBondContact O-N 3.08Å; V53-T56 VanDerWaalsContact O-N 3.11Å; V53-F57 HydrophobicContact CG1-CD2 3.64Å; V53-F57 HydrophobicContact CG1-CE2 3.67Å; V53-F57 VanDerWaalsContact O-CD2 3.23Å; V53-F57 WeakPolarHBondContact O-CD2 3.42Å; V53-F57 PolarHBondContact O-N 3.48Å; V53-V117 HydrophobicContact CG1-CG2 4.06Å
54	F	90.5	Very high	89.4	Confident	30 Å²	30	62 Å²	62	13%	0.132	31%	0.312	C	S	.	.	H	α-helix	trans	-52.1	-48.7	174.1	-93.9	-73.7	0	0	0	112	L50 N51 T56 F57 Y58 V117 D128	L50-F54 HydrophobicContact CD1-CD2 3.65Å; L50-F54 HydrophobicContact CD1-CE2 3.5Å; L50-F54 HydrophobicContact CD2-CE2 4.35Å; L50-F54 HydrophobicContact CG-CD2 3.81Å; L50-F54 HydrophobicContact CG-CE2 3.86Å; L50-F54 WeakPolarHBondContact O-CD2 3.49Å; L50-F54 PolarHBondContact O-N 3.45Å; N51-F54 PolarHBondContact O-N 3.33Å; F54-T56 PolarHBondContact O-N 3.27Å; F54-F57 PolarHBondContact O-N 2.95Å; F54-Y58 HydrophobicContact CD1-CD2 4.04Å; F54-Y58 AromaticContact CD1-CE2 3.73Å; F54-Y58 HydrophobicContact CD1-CE2 3.73Å; F54-Y58 HydrophobicContact CE1-CE2 4.16Å; F54-Y58 WeakPolarHBondContact O-CB 3.13Å; F54-Y58 WeakPolarHBondContact O-CD2 3.22Å; F54-Y58 PolarHBondContact O-N 3.4Å; F54-V117 HydrophobicContact CB-CG2 4.43Å; F54-V117 HydrophobicContact CD1-CB 4.39Å; F54-V117 HydrophobicContact CD1-CG1 3.99Å; F54-V117 HydrophobicContact CD1-CG2 3.63Å; F54-V117 HydrophobicContact CD2-CG2 3.63Å; F54-V117 HydrophobicContact CE1-CB 4.35Å; F54-V117 HydrophobicContact CE1-CG1 4.26Å; F54-V117 HydrophobicContact CE1-CG2 3.69Å; F54-V117 HydrophobicContact CE2-CG2 3.69Å; F54-V117 HydrophobicContact CG-CG2 3.61Å; F54-V117 HydrophobicContact CZ-CG2 3.71Å; F54-D128 HydrophobicContact CE1-CB 4.13Å
55	Y	89.4	Confident	88.8	Confident	141 Å²	141	63.5 Å²	63.5	55%	0.553	32%	0.316	S	S	*	.	H	α-helix	trans	-58.5	-48.4	177.1	-177.8	-92.6	0	0	0	111.8	N51 L52 V53 F57 Y58 Y59	N51-Y55 WeakPolarHBondContact O-CB 3.06Å; N51-Y55 PolarHBondContact O-N 3.03Å; L52-Y55 PolarHBondContact O-N 2.87Å; V53-Y55 VanDerWaalsContact C-N 3.3Å; V53-Y55 PolarHBondContact O-N 3.23Å; Y55-F57 PolarHBondContact O-N 2.92Å; Y55-Y58 PolarHBondContact O-N 3.14Å; Y55-Y59 HydrophobicContact CD1-CD2 4.34Å; Y55-Y59 AromaticContact CD2-CD2 3.37Å; Y55-Y59 HydrophobicContact CD2-CD2 3.37Å; Y55-Y59 AromaticContact CD2-CE2 3.39Å; Y55-Y59 HydrophobicContact CD2-CE2 3.39Å; Y55-Y59 HydrophobicContact CD2-CG 4.45Å; Y55-Y59 HydrophobicContact CE1-CD2 4.31Å; Y55-Y59 AromaticContact CE2-CD2 3.32Å; Y55-Y59 HydrophobicContact CE2-CD2 3.32Å; Y55-Y59 AromaticContact CE2-CE2 3.3Å; Y55-Y59 HydrophobicContact CE2-CE2 3.3Å; Y55-Y59 HydrophobicContact CE2-CG 4.09Å; Y55-Y59 AromaticContact CG-CD2 3.9Å; Y55-Y59 HydrophobicContact CG-CD2 3.9Å; Y55-Y59 HydrophobicContact CG-CE2 4.33Å; Y55-Y59 AromaticContact CZ-CD2 3.82Å; Y55-Y59 WeakPolarHBondContact O-CB 3.3Å; Y55-Y59 VanDerWaalsContact O-CD2 3.32Å; Y55-Y59 WeakPolarHBondContact O-CD2 3.47Å; Y55-Y59 PolarHBondContact O-N 3.2Å
56	T	90.1	Very high	88.2	Confident	56 Å²	56	66.1 Å²	66.1	34%	0.344	32%	0.317	S	S	.	.	H	α-helix	trans	-59.8	-46.5	-178.9	-57.6	0	0	0	0	111.3	L52 V53 F54 I60 L63	L52-T56 WeakPolarHBondContact O-CB 3.32Å; L52-T56 PolarHBondContact O-N 3.42Å; L52-T56 PolarHBondContact O-OG1 3.06Å; V53-T56 PolarHBondContact O-N 3.08Å; V53-T56 VanDerWaalsContact O-N 3.11Å; F54-T56 PolarHBondContact O-N 3.27Å; T56-I60 HydrophobicContact CG2-CD1 3.75Å; T56-I60 WeakPolarHBondContact O-CB 3.44Å; T56-I60 VanDerWaalsContact O-CG1 3.25Å; T56-I60 WeakPolarHBondContact O-CG1 3.4Å; T56-I60 PolarHBondContact O-N 3.31Å; T56-L63 HydrophobicContact CG2-CD2 4.31Å
57	F	85.7	Confident	87.5	Confident	15 Å²	15	66.2 Å²	66.2	7%	0.066	32%	0.317	C	S	.	.	H	α-helix	trans	-69.9	-43.9	-178.3	-82.8	-102.1	0	0	0	111.9	V53 F54 Y55 L63 N64 I67 V117 N118	V53-F57 HydrophobicContact CG1-CD2 3.64Å; V53-F57 HydrophobicContact CG1-CE2 3.67Å; V53-F57 VanDerWaalsContact O-CD2 3.23Å; V53-F57 WeakPolarHBondContact O-CD2 3.42Å; V53-F57 PolarHBondContact O-N 3.48Å; F54-F57 PolarHBondContact O-N 2.95Å; Y55-F57 PolarHBondContact O-N 2.92Å; F57-L63 HydrophobicContact CD1-CD2 3.99Å; F57-L63 HydrophobicContact CD1-CG 4.34Å; F57-L63 HydrophobicContact CD2-CD2 3.92Å; F57-L63 HydrophobicContact CE1-CD2 3.72Å; F57-L63 HydrophobicContact CE1-CG 3.96Å; F57-L63 HydrophobicContact CE2-CD2 3.7Å; F57-L63 HydrophobicContact CG-CD2 4.09Å; F57-L63 HydrophobicContact CZ-CD2 3.6Å; F57-L63 HydrophobicContact CZ-CG 4.22Å; F57-N64 WeakPolarHBondContact CD1-OD1 3.26Å; F57-N64 PolarHBondContact O-ND2 3.38Å; F57-I67 HydrophobicContact CD1-CD1 4.45Å; F57-I67 HydrophobicContact CE1-CD1 3.43Å; F57-I67 VanDerWaalsContact CE1-CD1 3.43Å; F57-I67 HydrophobicContact CZ-CD1 4.07Å; F57-V117 HydrophobicContact CB-CG1 3.48Å; F57-V117 VanDerWaalsContact CB-CG1 3.48Å; F57-V117 HydrophobicContact CD1-CG1 4.24Å; F57-V117 HydrophobicContact CD2-CG1 4.42Å; F57-V117 HydrophobicContact CG-CG1 3.79Å; F57-N118 WeakPolarHBondContact CE1-ND2 3.34Å; F57-N118 WeakPolarHBondContact CE1-OD1 3.4Å
58	Y	83.2	Confident	86.6	Confident	48 Å²	48	67.4 Å²	67.4	19%	0.188	33%	0.333	C	S	.	.	H	α-helix	trans	-67.4	-39.1	179.3	-88.7	-69.6	0	0	0	113.6	F54 Y55 Y121 A125 D128	F54-Y58 HydrophobicContact CD1-CD2 4.04Å; F54-Y58 AromaticContact CD1-CE2 3.73Å; F54-Y58 HydrophobicContact CD1-CE2 3.73Å; F54-Y58 HydrophobicContact CE1-CE2 4.16Å; F54-Y58 WeakPolarHBondContact O-CB 3.13Å; F54-Y58 WeakPolarHBondContact O-CD2 3.22Å; F54-Y58 PolarHBondContact O-N 3.4Å; Y55-Y58 PolarHBondContact O-N 3.14Å; Y58-Y121 AromaticContact CD1-CD2 3.89Å; Y58-Y121 HydrophobicContact CD1-CD2 3.89Å; Y58-Y121 AromaticContact CD1-CE2 3.57Å; Y58-Y121 HydrophobicContact CD1-CE2 3.57Å; Y58-Y121 AromaticContact CE1-CD2 3.52Å; Y58-Y121 HydrophobicContact CE1-CD2 3.52Å; Y58-Y121 AromaticContact CE1-CE2 3.56Å; Y58-Y121 HydrophobicContact CE1-CE2 3.56Å; Y58-Y121 HydrophobicContact CG-CD2 4.49Å; Y58-Y121 HydrophobicContact CG-CE2 4.34Å; Y58-Y121 AromaticContact CZ-CD2 3.87Å; Y58-Y121 PolarHBondContact OH-O 2.73Å; Y58-A125 HydrophobicContact CD1-CB 3.94Å; Y58-A125 HydrophobicContact CD2-CB 4.16Å; Y58-A125 HydrophobicContact CE1-CB 3.63Å; Y58-A125 HydrophobicContact CE2-CB 3.82Å; Y58-A125 HydrophobicContact CG-CB 4.22Å; Y58-A125 WeakPolarHBondContact OH-CA 3.33Å; Y58-A125 PolarHBondContact OH-N 3.02Å; Y58-A125 VanDerWaalsContact OH-N 3.12Å; Y58-D128 PolarHBondContact OH-OD2 3.26Å
59	Y	84.8	Confident	86	Confident	164 Å²	164	68.1 Å²	68.1	64%	0.643	34%	0.338	S	S	*	.	H	α-helix	trans	-90.6	-14.2	-176.5	-73.5	-82.1	0	0	0	114.1	Y55 P61	Y55-Y59 HydrophobicContact CD1-CD2 4.34Å; Y55-Y59 AromaticContact CD2-CD2 3.37Å; Y55-Y59 HydrophobicContact CD2-CD2 3.37Å; Y55-Y59 AromaticContact CD2-CE2 3.39Å; Y55-Y59 HydrophobicContact CD2-CE2 3.39Å; Y55-Y59 HydrophobicContact CD2-CG 4.45Å; Y55-Y59 HydrophobicContact CE1-CD2 4.31Å; Y55-Y59 AromaticContact CE2-CD2 3.32Å; Y55-Y59 HydrophobicContact CE2-CD2 3.32Å; Y55-Y59 AromaticContact CE2-CE2 3.3Å; Y55-Y59 HydrophobicContact CE2-CE2 3.3Å; Y55-Y59 HydrophobicContact CE2-CG 4.09Å; Y55-Y59 AromaticContact CG-CD2 3.9Å; Y55-Y59 HydrophobicContact CG-CD2 3.9Å; Y55-Y59 HydrophobicContact CG-CE2 4.33Å; Y55-Y59 AromaticContact CZ-CD2 3.82Å; Y55-Y59 WeakPolarHBondContact O-CB 3.3Å; Y55-Y59 VanDerWaalsContact O-CD2 3.32Å; Y55-Y59 WeakPolarHBondContact O-CD2 3.47Å; Y55-Y59 PolarHBondContact O-N 3.2Å; Y59-P61 VanDerWaalsContact C-CD 3.42Å; Y59-P61 WeakPolarHBondContact O-CD 3.4Å
60	I	87.8	Confident	85.6	Confident	84 Å²	84	69.3 Å²	69.3	43%	0.431	34%	0.343	S	S	.	.			trans	-109.6	79.2	173.9	-51	-179.9	0	0	0	108.8	T56 V62 L63	T56-I60 HydrophobicContact CG2-CD1 3.75Å; T56-I60 WeakPolarHBondContact O-CB 3.44Å; T56-I60 VanDerWaalsContact O-CG1 3.25Å; T56-I60 WeakPolarHBondContact O-CG1 3.4Å; T56-I60 PolarHBondContact O-N 3.31Å; I60-V62 HydrophobicContact CG2-CB 4.42Å; I60-V62 PolarHBondContact O-N 3.37Å; I60-V62 VanDerWaalsContact O-N 3.1Å; I60-L63 HydrophobicContact CB-CB 4.44Å; I60-L63 HydrophobicContact CG2-CB 4.15Å; I60-L63 WeakPolarHBondContact O-CB 3.23Å; I60-L63 PolarHBondContact O-N 3.01Å
61	P	77	Confident	85.1	Confident	63 Å²	63	71.6 Å²	71.6	41%	0.409	36%	0.355	S	S	.	.	H	α-helix	trans	-61.1	-26.1	-176.1	24.1	-34.7	0	0	0	113	Y59 L63 N64 Q65	Y59-P61 VanDerWaalsContact C-CD 3.42Å; Y59-P61 WeakPolarHBondContact O-CD 3.4Å; P61-L63 PolarHBondContact O-N 3.3Å; P61-N64 PolarHBondContact O-N 3.14Å; P61-Q65 WeakPolarHBondContact O-CG 3.21Å; P61-Q65 PolarHBondContact O-N 3.24Å
62	V	85.8	Confident	84.9	Confident	101 Å²	101	74.5 Å²	74.5	61%	0.612	36%	0.359	S	S	*	.	H	α-helix	trans	-57.6	-38	175.1	179.9	0	0	0	0	111.4	I60 Q65 W66	I60-V62 HydrophobicContact CG2-CB 4.42Å; I60-V62 PolarHBondContact O-N 3.37Å; I60-V62 VanDerWaalsContact O-N 3.1Å; V62-Q65 PolarHBondContact O-N 2.99Å; V62-W66 WeakPolarHBondContact O-CB 3.22Å; V62-W66 PolarHBondContact O-N 3.34Å
63	L	82	Confident	84.6	Confident	55 Å²	55	70.9 Å²	70.9	29%	0.288	34%	0.341	S	S	.	.	H	α-helix	trans	-66.5	-45.1	-179.8	-174.4	62.8	0	0	0	110.9	T56 F57 I60 P61 W66 I67	T56-L63 HydrophobicContact CG2-CD2 4.31Å; F57-L63 HydrophobicContact CD1-CD2 3.99Å; F57-L63 HydrophobicContact CD1-CG 4.34Å; F57-L63 HydrophobicContact CD2-CD2 3.92Å; F57-L63 HydrophobicContact CE1-CD2 3.72Å; F57-L63 HydrophobicContact CE1-CG 3.96Å; F57-L63 HydrophobicContact CE2-CD2 3.7Å; F57-L63 HydrophobicContact CG-CD2 4.09Å; F57-L63 HydrophobicContact CZ-CD2 3.6Å; F57-L63 HydrophobicContact CZ-CG 4.22Å; I60-L63 HydrophobicContact CB-CB 4.44Å; I60-L63 HydrophobicContact CG2-CB 4.15Å; I60-L63 WeakPolarHBondContact O-CB 3.23Å; I60-L63 PolarHBondContact O-N 3.01Å; P61-L63 PolarHBondContact O-N 3.3Å; L63-W66 PolarHBondContact O-N 2.98Å; L63-I67 HydrophobicContact CD1-CD1 4.38Å; L63-I67 HydrophobicContact CG-CD1 4.22Å; L63-I67 WeakPolarHBondContact O-CG1 3.45Å; L63-I67 PolarHBondContact O-N 3.41Å
64	N	74.8	Confident	84.4	Confident	14 Å²	14	70.2 Å²	70.2	8%	0.075	34%	0.337	C	S	.	.	H	α-helix	trans	-65.3	-41.1	176.5	-82.7	-37.3	0	0	0	112.7	F57 P61 W66 I67 G68 Y121	F57-N64 WeakPolarHBondContact CD1-OD1 3.26Å; F57-N64 PolarHBondContact O-ND2 3.38Å; P61-N64 PolarHBondContact O-N 3.14Å; N64-W66 VanDerWaalsContact C-N 3.31Å; N64-W66 PolarHBondContact O-N 2.88Å; N64-I67 PolarHBondContact O-N 2.94Å; N64-G68 PolarHBondContact O-N 3.42Å; N64-Y121 HydrophobicContact CB-CD1 4.3Å; N64-Y121 HydrophobicContact CB-CE1 3.95Å; N64-Y121 WeakPolarHBondContact ND2-CD2 3.47Å; N64-Y121 WeakPolarHBondContact ND2-CE2 3.34Å
65	Q	80.2	Confident	84.3	Confident	126 Å²	126	73.3 Å²	73.3	59%	0.589	35%	0.349	S	S	*	.	H	α-helix	trans	-61.8	-42.2	175.5	-72.9	176.2	-1.5	0	0	111.3	P61 V62 I67 G68 Q69	P61-Q65 WeakPolarHBondContact O-CG 3.21Å; P61-Q65 PolarHBondContact O-N 3.24Å; V62-Q65 PolarHBondContact O-N 2.99Å; Q65-I67 PolarHBondContact O-N 2.91Å; Q65-G68 PolarHBondContact O-N 2.91Å; Q65-Q69 WeakPolarHBondContact O-CG 3.5Å; Q65-Q69 PolarHBondContact O-N 3.34Å
66	W	83	Confident	84.4	Confident	117 Å²	117	70.5 Å²	70.5	44%	0.443	34%	0.343	S	S	.	.	H	α-helix	trans	-62.5	-42.3	177.3	-172.9	82.5	0	0	0	111.8	V62 L63 N64 Q69 H70	V62-W66 WeakPolarHBondContact O-CB 3.22Å; V62-W66 PolarHBondContact O-N 3.34Å; L63-W66 PolarHBondContact O-N 2.98Å; N64-W66 VanDerWaalsContact C-N 3.31Å; N64-W66 PolarHBondContact O-N 2.88Å; W66-Q69 PolarHBondContact O-N 3.18Å; W66-H70 AromaticContact CD1-CD2 3.58Å; W66-H70 AromaticContact CD1-NE2 3.99Å; W66-H70 AromaticContact CD2-CD2 3.82Å; W66-H70 AromaticContact CE2-CD2 3.39Å; W66-H70 AromaticContact CG-CD2 3.94Å; W66-H70 AromaticContact CZ2-CD2 3.87Å; W66-H70 AromaticContact NE1-CD2 3.24Å; W66-H70 PolarHBondContact NE1-CD2 3.47Å; W66-H70 AromaticContact NE1-NE2 3.59Å; W66-H70 WeakPolarHBondContact O-CB 3.49Å; W66-H70 PolarHBondContact O-CD2 2.87Å; W66-H70 VanDerWaalsContact O-CD2 3.3Å; W66-H70 PolarHBondContact O-N 2.92Å
67	I	80.8	Confident	84.5	Confident	6 Å²	6	69.4 Å²	69.4	3%	0.031	34%	0.335	C	S	.	.	H	α-helix	trans	-70.2	-38.6	179.2	-66.5	166.5	0	0	0	111.6	F57 L63 N64 Q65 Q69 H70 I71 M74 N118	F57-I67 HydrophobicContact CD1-CD1 4.45Å; F57-I67 HydrophobicContact CE1-CD1 3.43Å; F57-I67 VanDerWaalsContact CE1-CD1 3.43Å; F57-I67 HydrophobicContact CZ-CD1 4.07Å; L63-I67 HydrophobicContact CD1-CD1 4.38Å; L63-I67 HydrophobicContact CG-CD1 4.22Å; L63-I67 WeakPolarHBondContact O-CG1 3.45Å; L63-I67 PolarHBondContact O-N 3.41Å; N64-I67 PolarHBondContact O-N 2.94Å; Q65-I67 PolarHBondContact O-N 2.91Å; I67-Q69 PolarHBondContact O-N 3.48Å; I67-H70 CarbonylContact O-C 3.59Å; I67-H70 PolarHBondContact O-N 2.98Å; I67-H70 VanDerWaalsContact O-N 3.08Å; I67-I71 PolarHBondContact O-N 2.88Å; I67-M74 HydrophobicContact CG2-CG 3.67Å; I67-M74 HydrophobicContact CG2-SD 3.81Å; I67-N118 WeakPolarHBondContact CD1-OD1 3.45Å; I67-N118 HydrophobicContact CG2-CB 4.5Å; I67-N118 WeakPolarHBondContact CG2-OD1 3.44Å
68	G	76.3	Confident	84.7	Confident	43 Å²	43	69.8 Å²	69.8	44%	0.443	34%	0.339	S	S	.	.	H	α-helix	trans	-60.1	-35.6	172.7	0	0	0	0	0	112.6	N64 Q65	N64-G68 PolarHBondContact O-N 3.42Å; Q65-G68 PolarHBondContact O-N 2.91Å
69	Q	84.2	Confident	85.1	Confident	145 Å²	145	73.2 Å²	73.2	68%	0.678	36%	0.36	S	S	*	.	H	α-helix	trans	-76	-26.8	174.1	-69.8	175.4	3.2	0	0	113.1	Q65 W66 I67	Q65-Q69 WeakPolarHBondContact O-CG 3.5Å; Q65-Q69 PolarHBondContact O-N 3.34Å; W66-Q69 PolarHBondContact O-N 3.18Å; I67-Q69 PolarHBondContact O-N 3.48Å
70	H	86.6	Confident	85.5	Confident	62 Å²	62	68.5 Å²	68.5	29%	0.287	35%	0.345	S	S	.	.			trans	-124.2	61.4	-174	-63.6	-52.6	0	0	0	111.3	W66 I67 W72 S73	W66-H70 AromaticContact CD1-CD2 3.58Å; W66-H70 AromaticContact CD1-NE2 3.99Å; W66-H70 AromaticContact CD2-CD2 3.82Å; W66-H70 AromaticContact CE2-CD2 3.39Å; W66-H70 AromaticContact CG-CD2 3.94Å; W66-H70 AromaticContact CZ2-CD2 3.87Å; W66-H70 AromaticContact NE1-CD2 3.24Å; W66-H70 PolarHBondContact NE1-CD2 3.47Å; W66-H70 AromaticContact NE1-NE2 3.59Å; W66-H70 WeakPolarHBondContact O-CB 3.49Å; W66-H70 PolarHBondContact O-CD2 2.87Å; W66-H70 VanDerWaalsContact O-CD2 3.3Å; W66-H70 PolarHBondContact O-N 2.92Å; I67-H70 CarbonylContact O-C 3.59Å; I67-H70 PolarHBondContact O-N 2.98Å; I67-H70 VanDerWaalsContact O-N 3.08Å; H70-W72 AromaticContact CG-NE1 3.76Å; H70-W72 AromaticContact ND1-NE1 3.64Å; H70-W72 PolarHBondContact O-N 3.05Å; H70-S73 VanDerWaalsContact O-CB 3.27Å; H70-S73 WeakPolarHBondContact O-CB 3.44Å; H70-S73 PolarHBondContact O-N 3.47Å; H70-S73 PolarHBondContact O-OG 3.32Å
71	I	85.3	Confident	85.8	Confident	48 Å²	48	64.5 Å²	64.5	25%	0.246	33%	0.325	C	S	.	.	T	Hydrogen-bonded Turn	trans	-55.2	-25.8	179.7	-164.7	62.4	0	0	0	112.9	I67 S73 M74 Y253	I67-I71 PolarHBondContact O-N 2.88Å; I71-S73 PolarHBondContact O-N 3.29Å; I71-M74 HydrophobicContact CD1-CB 4.41Å; I71-M74 HydrophobicContact CD1-CG 4.18Å; I71-M74 WeakPolarHBondContact O-CB 3.47Å; I71-M74 PolarHBondContact O-N 2.84Å; I71-Y253 HydrophobicContact CD1-CE1 4.16Å
72	W	87.2	Confident	86.5	Confident	147 Å²	147	61.8 Å²	61.8	56%	0.557	31%	0.309	S	S	*	.	H	α-helix	trans	-57.1	-29.6	174.3	73.3	-94.6	0	0	0	113.4	H70 M74 Y75 L76	H70-W72 AromaticContact CG-NE1 3.76Å; H70-W72 AromaticContact ND1-NE1 3.64Å; H70-W72 PolarHBondContact O-N 3.05Å; W72-M74 PolarHBondContact O-N 3.43Å; W72-Y75 PolarHBondContact O-N 3.5Å; W72-L76 HydrophobicContact CZ3-CD2 3.97Å; W72-L76 PolarHBondContact O-N 3.02Å; W72-L76 VanDerWaalsContact O-N 3.1Å
73	S	88	Confident	86.7	Confident	10 Å²	10	64.5 Å²	64.5	7%	0.07	31%	0.309	C	S	.	.	H	α-helix	trans	-62.7	-32.7	176	66.8	0	0	0	0	112	H70 I71 L76 L77	H70-S73 VanDerWaalsContact O-CB 3.27Å; H70-S73 WeakPolarHBondContact O-CB 3.44Å; H70-S73 PolarHBondContact O-N 3.47Å; H70-S73 PolarHBondContact O-OG 3.32Å; I71-S73 PolarHBondContact O-N 3.29Å; S73-L76 WeakPolarHBondContact O-CB 3.38Å; S73-L76 PolarHBondContact O-N 3.2Å; S73-L77 WeakPolarHBondContact O-CG 3.29Å; S73-L77 PolarHBondContact O-N 3.06Å
74	M	89	Confident	87.2	Confident	0 Å²	0	62.5 Å²	62.5	0%	0	30%	0.298	C	S	.	.	H	α-helix	trans	-69.8	-40.3	176.5	-68.5	-65.7	-67.8	0	0	111.9	I67 I71 W72 L76 L77 C78 I115 N118 I119 L256	I67-M74 HydrophobicContact CG2-CG 3.67Å; I67-M74 HydrophobicContact CG2-SD 3.81Å; I71-M74 HydrophobicContact CD1-CB 4.41Å; I71-M74 HydrophobicContact CD1-CG 4.18Å; I71-M74 WeakPolarHBondContact O-CB 3.47Å; I71-M74 PolarHBondContact O-N 2.84Å; W72-M74 PolarHBondContact O-N 3.43Å; M74-L76 VanDerWaalsContact C-N 3.29Å; M74-L76 PolarHBondContact O-N 3.15Å; M74-L77 PolarHBondContact O-N 3.43Å; M74-L77 HydrophobicContact SD-CD1 4.13Å; M74-C78 PolarHBondContact O-N 3.02Å; M74-C78 PolarHBondContact O-SG 3.09Å; M74-C78 VanDerWaalsContact O-SG 3.4Å; M74-I115 HydrophobicContact CE-CB 4.28Å; M74-I115 HydrophobicContact CE-CG1 4.49Å; M74-I115 HydrophobicContact CE-CG2 3.99Å; M74-I115 WeakPolarHBondContact CE-O 3.33Å; M74-N118 HydrophobicContact CE-CB 3.5Å; M74-N118 VanDerWaalsContact CE-CB 3.5Å; M74-N118 HydrophobicContact SD-CB 3.58Å; M74-N118 VanDerWaalsContact SD-CB 3.58Å; M74-I119 HydrophobicContact CE-CG1 4.25Å; M74-L256 HydrophobicContact CB-CD1 4.35Å; M74-L256 HydrophobicContact CB-CD2 3.64Å; M74-L256 HydrophobicContact CE-CD2 3.51Å; M74-L256 HydrophobicContact CG-CD2 4.05Å
75	Y	89.2	Confident	87.9	Confident	94 Å²	94	61.8 Å²	61.8	37%	0.369	30%	0.295	S	S	.	.	H	α-helix	trans	-63.1	-39.2	173.5	-62.1	-56.9	0	0	0	111.5	W72 C78 L79 L256	W72-Y75 PolarHBondContact O-N 3.5Å; Y75-C78 PolarHBondContact O-N 3.39Å; Y75-L79 PolarHBondContact O-N 2.83Å; Y75-L256 HydrophobicContact CD1-CD1 3.87Å; Y75-L256 HydrophobicContact CE1-CD1 3.78Å
76	L	91	Very high	88.2	Confident	83 Å²	83	58.6 Å²	58.6	44%	0.435	28%	0.284	S	S	.	.	H	α-helix	trans	-63.1	-44.9	174.3	-178.1	65.3	0	0	0	111.5	W72 S73 M74 C78 L79 L80	W72-L76 HydrophobicContact CZ3-CD2 3.97Å; W72-L76 PolarHBondContact O-N 3.02Å; W72-L76 VanDerWaalsContact O-N 3.1Å; S73-L76 WeakPolarHBondContact O-CB 3.38Å; S73-L76 PolarHBondContact O-N 3.2Å; M74-L76 VanDerWaalsContact C-N 3.29Å; M74-L76 PolarHBondContact O-N 3.15Å; L76-C78 VanDerWaalsContact C-N 3.35Å; L76-C78 PolarHBondContact O-N 3.36Å; L76-L79 PolarHBondContact O-N 3.27Å; L76-L80 HydrophobicContact CD1-CD1 4.38Å; L76-L80 HydrophobicContact CD1-CG 4.33Å; L76-L80 HydrophobicContact CG-CD1 4.06Å; L76-L80 HydrophobicContact CG-CG 4.4Å; L76-L80 WeakPolarHBondContact O-CB 3.29Å; L76-L80 WeakPolarHBondContact O-CG 3.41Å; L76-L80 PolarHBondContact O-N 3.43Å
77	L	92.1	Very high	88.5	Confident	33 Å²	33	54.6 Å²	54.6	17%	0.173	27%	0.27	C	S	.	.	H	α-helix	trans	-60	-43.8	175.7	-75	173.1	0	0	0	111.6	S73 M74 L79 L80 N81 F111 I115	S73-L77 WeakPolarHBondContact O-CG 3.29Å; S73-L77 PolarHBondContact O-N 3.06Å; M74-L77 PolarHBondContact O-N 3.43Å; M74-L77 HydrophobicContact SD-CD1 4.13Å; L77-L79 VanDerWaalsContact C-N 3.34Å; L77-L79 PolarHBondContact O-N 2.93Å; L77-L80 PolarHBondContact O-N 3.26Å; L77-N81 WeakPolarHBondContact O-CB 3.3Å; L77-N81 PolarHBondContact O-N 3.13Å; L77-F111 HydrophobicContact CD2-CD1 3.89Å; L77-F111 HydrophobicContact CD2-CE1 4.3Å; L77-F111 HydrophobicContact CD2-CG 4.29Å; L77-I115 HydrophobicContact CB-CD1 4.13Å; L77-I115 HydrophobicContact CB-CG1 3.81Å
78	C	90.9	Very high	88.7	Confident	23 Å²	23	54.4 Å²	54.4	16%	0.155	27%	0.27	C	S	.	.	H	α-helix	trans	-58.9	-44.5	175.2	-74.7	0	0	0	0	111.8	M74 Y75 L76 N81 G82	M74-C78 PolarHBondContact O-N 3.02Å; M74-C78 PolarHBondContact O-SG 3.09Å; M74-C78 VanDerWaalsContact O-SG 3.4Å; Y75-C78 PolarHBondContact O-N 3.39Å; L76-C78 VanDerWaalsContact C-N 3.35Å; L76-C78 PolarHBondContact O-N 3.36Å; C78-N81 PolarHBondContact O-N 2.97Å; C78-G82 PolarHBondContact O-N 2.88Å
79	L	91.5	Very high	89	Confident	120 Å²	120	52.6 Å²	52.6	63%	0.628	25%	0.25	S	C	*	.	H	α-helix	trans	-64.7	-46.7	178.7	-172.7	150.5	0	0	0	111.6	Y75 L76 L77 G82 Y83	Y75-L79 PolarHBondContact O-N 2.83Å; L76-L79 PolarHBondContact O-N 3.27Å; L77-L79 VanDerWaalsContact C-N 3.34Å; L77-L79 PolarHBondContact O-N 2.93Å; L79-G82 PolarHBondContact O-N 3.47Å; L79-Y83 WeakPolarHBondContact O-CB 3.15Å; L79-Y83 PolarHBondContact O-N 2.94Å
80	L	94	Very high	88.7	Confident	64 Å²	64	52.4 Å²	52.4	34%	0.335	25%	0.247	S	C	.	.	H	α-helix	trans	-64	-41.6	177.5	-70	175.3	0	0	0	111.8	L76 L77 G82 Y83 N84 F111	L76-L80 HydrophobicContact CD1-CD1 4.38Å; L76-L80 HydrophobicContact CD1-CG 4.33Å; L76-L80 HydrophobicContact CG-CD1 4.06Å; L76-L80 HydrophobicContact CG-CG 4.4Å; L76-L80 WeakPolarHBondContact O-CB 3.29Å; L76-L80 WeakPolarHBondContact O-CG 3.41Å; L76-L80 PolarHBondContact O-N 3.43Å; L77-L80 PolarHBondContact O-N 3.26Å; L80-G82 VanDerWaalsContact C-N 3.34Å; L80-Y83 PolarHBondContact O-N 3.3Å; L80-N84 VanDerWaalsContact O-CB 3.29Å; L80-N84 WeakPolarHBondContact O-CB 3.46Å; L80-N84 PolarHBondContact O-N 3.13Å; L80-F111 HydrophobicContact CB-CD2 3.95Å; L80-F111 HydrophobicContact CB-CE2 3.81Å; L80-F111 HydrophobicContact CD1-CE2 4.23Å; L80-F111 HydrophobicContact CD1-CZ 4.38Å
81	N	93.3	Very high	88.2	Confident	1 Å²	1	52.6 Å²	52.6	1%	0.005	25%	0.249	C	C	.	.	H	α-helix	trans	-62.6	-43.3	176.5	-169.6	63.7	0	0	0	111.4	L77 C78 N84 A85 F108 F111 H112 I115	L77-N81 WeakPolarHBondContact O-CB 3.3Å; L77-N81 PolarHBondContact O-N 3.13Å; C78-N81 PolarHBondContact O-N 2.97Å; N81-N84 PolarHBondContact O-N 2.99Å; N81-A85 WeakPolarHBondContact O-CB 3.47Å; N81-A85 PolarHBondContact O-N 3.45Å; N81-F108 WeakPolarHBondContact ND2-CE2 3.34Å; N81-F108 WeakPolarHBondContact OD1-CD2 3.27Å; N81-F108 VanDerWaalsContact OD1-CE2 3.31Å; N81-F108 WeakPolarHBondContact OD1-CE2 2.89Å; N81-F108 PolarHBondContact OD1-O 3.15Å; N81-F111 HydrophobicContact CB-CB 4.09Å; N81-H112 PolarHBondContact ND2-ND1 2.98Å; N81-H112 PolarHBondContact OD1-N 3.37Å; N81-I115 HydrophobicContact CB-CD1 3.91Å
82	G	90.9	Very high	87.3	Confident	6 Å²	6	53.4 Å²	53.4	6%	0.062	26%	0.257	C	S	.	.	H	α-helix	trans	-66	-42.5	177.2	0	0	0	0	0	113	C78 L79 L80 N84 A85 V86	C78-G82 PolarHBondContact O-N 2.88Å; L79-G82 PolarHBondContact O-N 3.47Å; L80-G82 VanDerWaalsContact C-N 3.34Å; G82-N84 VanDerWaalsContact C-N 3.34Å; G82-N84 PolarHBondContact O-N 3.31Å; G82-A85 PolarHBondContact O-N 2.91Å; G82-V86 WeakPolarHBondContact O-CG2 3.31Å; G82-V86 PolarHBondContact O-N 2.9Å
83	Y	91.2	Very high	86.7	Confident	157 Å²	157	52.7 Å²	52.7	62%	0.616	26%	0.264	S	S	*	.	H	α-helix	trans	-60.2	-44.6	174.2	179.9	-108.5	0	0	0	111.9	L79 L80 A85 V86 I87	L79-Y83 WeakPolarHBondContact O-CB 3.15Å; L79-Y83 PolarHBondContact O-N 2.94Å; L80-Y83 PolarHBondContact O-N 3.3Å; Y83-A85 PolarHBondContact O-N 3.47Å; Y83-V86 PolarHBondContact O-N 3.01Å; Y83-I87 HydrophobicContact CD1-CD1 3.8Å; Y83-I87 HydrophobicContact CE1-CD1 3.32Å; Y83-I87 HydrophobicContact CE1-CG1 4.3Å; Y83-I87 HydrophobicContact CE2-CD1 4.43Å; Y83-I87 PolarHBondContact O-N 2.67Å
84	N	91.1	Very high	85.8	Confident	13 Å²	13	54 Å²	54	7%	0.07	27%	0.27	C	S	.	.	H	α-helix	trans	-62.1	-44.1	178.4	-166.1	-2.8	0	0	0	112	L80 N81 G82 V86 I87 L88 I104 V107 F108	L80-N84 VanDerWaalsContact O-CB 3.29Å; L80-N84 WeakPolarHBondContact O-CB 3.46Å; L80-N84 PolarHBondContact O-N 3.13Å; N81-N84 PolarHBondContact O-N 2.99Å; G82-N84 VanDerWaalsContact C-N 3.34Å; G82-N84 PolarHBondContact O-N 3.31Å; N84-V86 VanDerWaalsContact C-N 3.34Å; N84-V86 PolarHBondContact O-N 2.82Å; N84-I87 WeakPolarHBondContact O-CB 3.36Å; N84-I87 PolarHBondContact O-N 2.64Å; N84-L88 PolarHBondContact O-N 2.97Å; N84-I104 PolarHBondContact ND2-O 2.84Å; N84-I104 WeakPolarHBondContact OD1-CG2 3.49Å; N84-I104 PolarHBondContact OD1-O 3.23Å; N84-V107 WeakPolarHBondContact ND2-CG1 3.41Å; N84-F108 WeakPolarHBondContact ND2-CA 3.41Å; N84-F108 PolarHBondContact ND2-N 3.49Å
85	A	90.7	Very high	84.8	Confident	0 Å²	0	54 Å²	54	0%	0	27%	0.271	C	S	.	.	H	α-helix	trans	-62	-40.5	175.3	0	0	0	0	0	112.6	N81 G82 Y83 I87 L88 L89 F108 L267	N81-A85 WeakPolarHBondContact O-CB 3.47Å; N81-A85 PolarHBondContact O-N 3.45Å; G82-A85 PolarHBondContact O-N 2.91Å; Y83-A85 PolarHBondContact O-N 3.47Å; A85-I87 VanDerWaalsContact C-N 3.32Å; A85-I87 PolarHBondContact O-N 2.82Å; A85-L88 PolarHBondContact O-N 3.17Å; A85-L89 WeakPolarHBondContact O-CB 3.32Å; A85-L89 VanDerWaalsContact O-CD1 3.27Å; A85-L89 WeakPolarHBondContact O-CD1 3.27Å; A85-L89 WeakPolarHBondContact O-CG 3.16Å; A85-L89 PolarHBondContact O-N 2.62Å; A85-F108 HydrophobicContact CB-CD2 4.01Å; A85-F108 HydrophobicContact CB-CE2 3.7Å; A85-L267 HydrophobicContact CB-CD1 3.35Å; A85-L267 HydrophobicContact CB-CD2 4.05Å; A85-L267 HydrophobicContact CB-CG 4.27Å
86	V	87.1	Confident	84.1	Confident	59 Å²	59	53.3 Å²	53.3	36%	0.358	27%	0.267	S	S	.	.	H	α-helix	trans	-64.1	-36.8	176.5	172.2	0	0	0	0	111.9	G82 Y83 N84 L89 K90	G82-V86 WeakPolarHBondContact O-CG2 3.31Å; G82-V86 PolarHBondContact O-N 2.9Å; Y83-V86 PolarHBondContact O-N 3.01Å; N84-V86 VanDerWaalsContact C-N 3.34Å; N84-V86 PolarHBondContact O-N 2.82Å; V86-L89 PolarHBondContact O-N 3.24Å; V86-K90 HydrophobicContact CG1-CD 4.04Å; V86-K90 HydrophobicContact CG1-CG 4.22Å; V86-K90 WeakPolarHBondContact O-CB 3.47Å; V86-K90 PolarHBondContact O-N 3.13Å
87	I	87.7	Confident	83.5	Confident	32 Å²	32	55.8 Å²	55.8	16%	0.164	28%	0.275	C	S	.	.	H	α-helix	trans	-59.3	-49.4	174.1	-73.8	169.7	0	0	0	110.6	Y83 N84 A85 L89 I91 I94 I104	Y83-I87 HydrophobicContact CD1-CD1 3.8Å; Y83-I87 HydrophobicContact CE1-CD1 3.32Å; Y83-I87 HydrophobicContact CE1-CG1 4.3Å; Y83-I87 HydrophobicContact CE2-CD1 4.43Å; Y83-I87 PolarHBondContact O-N 2.67Å; N84-I87 WeakPolarHBondContact O-CB 3.36Å; N84-I87 PolarHBondContact O-N 2.64Å; A85-I87 VanDerWaalsContact C-N 3.32Å; A85-I87 PolarHBondContact O-N 2.82Å; I87-L89 VanDerWaalsContact C-N 3.27Å; I87-L89 PolarHBondContact O-N 3.25Å; I87-I91 HydrophobicContact CG2-CD1 4.33Å; I87-I91 WeakPolarHBondContact O-CB 3.27Å; I87-I91 PolarHBondContact O-N 2.73Å; I87-I94 HydrophobicContact CG2-CD1 4.01Å; I87-I94 HydrophobicContact CG2-CG2 4.22Å; I87-I104 HydrophobicContact CG2-CD1 4.2Å; I87-I104 HydrophobicContact CG2-CG2 4.39Å
88	L	86.1	Confident	82.9	Confident	2 Å²	2	61 Å²	61	1%	0.01	30%	0.296	C	S	.	.	H	α-helix	trans	-62.2	-35.1	178.2	-72.7	171.8	0	0	0	112.2	N84 A85 I104 L105 V224 M228	N84-L88 PolarHBondContact O-N 2.97Å; A85-L88 PolarHBondContact O-N 3.17Å; L88-I104 HydrophobicContact CD1-CG2 4Å; L88-I104 HydrophobicContact CD2-CB 4.11Å; L88-I104 HydrophobicContact CD2-CG2 3.51Å; L88-I104 HydrophobicContact CG-CG2 3.54Å; L88-L105 HydrophobicContact CD1-CD1 4.17Å; L88-V224 HydrophobicContact CD2-CG1 4.12Å; L88-M228 HydrophobicContact CB-SD 4.16Å; L88-M228 HydrophobicContact CD1-SD 3.67Å
89	L	82.5	Confident	82.7	Confident	6 Å²	6	63 Å²	63	3%	0.031	31%	0.309	C	S	.	.	H	α-helix	trans	-79.9	-38.8	-176.7	-73	162.2	0	0	0	114	A85 V86 I87 L225 M228 L267 F270 S271 I274	A85-L89 WeakPolarHBondContact O-CB 3.32Å; A85-L89 VanDerWaalsContact O-CD1 3.27Å; A85-L89 WeakPolarHBondContact O-CD1 3.27Å; A85-L89 WeakPolarHBondContact O-CG 3.16Å; A85-L89 PolarHBondContact O-N 2.62Å; V86-L89 PolarHBondContact O-N 3.24Å; I87-L89 VanDerWaalsContact C-N 3.27Å; I87-L89 PolarHBondContact O-N 3.25Å; L89-L225 HydrophobicContact CD2-CD1 3.52Å; L89-L225 HydrophobicContact CG-CD1 4.41Å; L89-M228 HydrophobicContact CD1-CE 4.2Å; L89-M228 HydrophobicContact CD2-CE 4.03Å; L89-M228 HydrophobicContact CG-CE 4.02Å; L89-L267 HydrophobicContact CD1-CD1 4.1Å; L89-L267 HydrophobicContact CD1-CD2 4.19Å; L89-L267 HydrophobicContact CD1-CG 3.89Å; L89-F270 HydrophobicContact CB-CD1 4.43Å; L89-F270 HydrophobicContact CB-CE1 4.22Å; L89-F270 HydrophobicContact CD1-CD1 4.1Å; L89-S271 VanDerWaalsContact CD2-CB 3.48Å; L89-S271 VanDerWaalsContact CD2-OG 3.24Å; L89-S271 WeakPolarHBondContact CD2-OG 3.41Å; L89-I274 HydrophobicContact CB-CD1 3.79Å; L89-I274 HydrophobicContact CD2-CD1 3.92Å; L89-I274 HydrophobicContact CG-CD1 4.46Å; L89-I274 WeakPolarHBondContact O-CD1 3.18Å
90	K	77.6	Confident	82.4	Confident	140 Å²	140	60.4 Å²	60.4	61%	0.609	30%	0.295	S	S	*	.	H	α-helix	trans	-98.3	-19.6	-170.5	-76.6	-163	173.3	-169.1	0	114.7	V86 P92 F270	V86-K90 HydrophobicContact CG1-CD 4.04Å; V86-K90 HydrophobicContact CG1-CG 4.22Å; V86-K90 WeakPolarHBondContact O-CB 3.47Å; V86-K90 PolarHBondContact O-N 3.13Å; K90-P92 WeakPolarHBondContact O-CD 3.35Å; K90-F270 HydrophobicContact CG-CE1 4.36Å
91	I	75.9	Confident	82.2	Confident	67 Å²	67	57.5 Å²	57.5	34%	0.344	28%	0.28	S	S	.	.			trans	-110	86	-172.8	-50.4	179.1	0	0	0	109	I87 N93 I94 E95	I87-I91 HydrophobicContact CG2-CD1 4.33Å; I87-I91 WeakPolarHBondContact O-CB 3.27Å; I87-I91 PolarHBondContact O-N 2.73Å; I91-N93 HydrophobicContact CG2-CB 4.37Å; I91-N93 PolarHBondContact O-N 3.45Å; I91-N93 VanDerWaalsContact O-N 3.12Å; I91-I94 HydrophobicContact CB-CB 4.16Å; I91-I94 HydrophobicContact CB-CD1 4.02Å; I91-I94 HydrophobicContact CB-CG1 4.19Å; I91-I94 HydrophobicContact CD1-CD1 3.81Å; I91-I94 HydrophobicContact CG2-CB 3.96Å; I91-I94 HydrophobicContact CG2-CD1 3.67Å; I91-I94 HydrophobicContact CG2-CG1 3.58Å; I91-I94 PolarHBondContact O-N 3Å; I91-E95 PolarHBondContact O-N 2.91Å; I91-E95 VanDerWaalsContact O-N 3.12Å
92	P	67.4	Low	81.9	Confident	64 Å²	64	59.8 Å²	59.8	42%	0.416	29%	0.294	S	S	.	.	H	α-helix	trans	-60.1	-28.9	-176.1	22.3	-33.2	0	0	0	112.4	K90 I94 E95 R96	K90-P92 WeakPolarHBondContact O-CD 3.35Å; P92-I94 VanDerWaalsContact C-N 3.32Å; P92-I94 PolarHBondContact O-N 3.43Å; P92-E95 PolarHBondContact O-N 3.37Å; P92-R96 WeakPolarHBondContact O-CD 3.44Å; P92-R96 VanDerWaalsContact O-CG 3.3Å; P92-R96 WeakPolarHBondContact O-CG 3.45Å; P92-R96 PolarHBondContact O-N 3.26Å
93	N	72.9	Confident	81.9	Confident	132 Å²	132	64.1 Å²	64.1	71%	0.706	32%	0.315	S	S	*	.	H	α-helix	trans	-62.3	-39.7	174.4	-66.2	-15.4	0	0	0	112	I91 F97	I91-N93 HydrophobicContact CG2-CB 4.37Å; I91-N93 PolarHBondContact O-N 3.45Å; I91-N93 VanDerWaalsContact O-N 3.12Å; N93-F97 WeakPolarHBondContact O-CB 3.4Å; N93-F97 PolarHBondContact O-N 3.43Å
94	I	70.5	Confident	82	Confident	37 Å²	37	57.8 Å²	57.8	19%	0.19	29%	0.291	C	S	.	.	H	α-helix	trans	-76.3	-41	-179.1	-70.9	177	0	0	0	110.1	I87 I91 P92 R96 F97 L100 N101 I104	I87-I94 HydrophobicContact CG2-CD1 4.01Å; I87-I94 HydrophobicContact CG2-CG2 4.22Å; I91-I94 HydrophobicContact CB-CB 4.16Å; I91-I94 HydrophobicContact CB-CD1 4.02Å; I91-I94 HydrophobicContact CB-CG1 4.19Å; I91-I94 HydrophobicContact CD1-CD1 3.81Å; I91-I94 HydrophobicContact CG2-CB 3.96Å; I91-I94 HydrophobicContact CG2-CD1 3.67Å; I91-I94 HydrophobicContact CG2-CG1 3.58Å; I91-I94 PolarHBondContact O-N 3Å; P92-I94 VanDerWaalsContact C-N 3.32Å; P92-I94 PolarHBondContact O-N 3.43Å; I94-R96 PolarHBondContact O-N 2.97Å; I94-F97 PolarHBondContact O-N 3.46Å; I94-L100 HydrophobicContact CG1-CD2 4.09Å; I94-L100 HydrophobicContact CG2-CD2 4.02Å; I94-L100 HydrophobicContact CG2-CG 4.24Å; I94-N101 WeakPolarHBondContact O-CB 3.39Å; I94-I104 HydrophobicContact CG2-CD1 3.32Å
95	E	68.2	Low	82.1	Confident	2 Å²	2	57.4 Å²	57.4	1%	0.009	29%	0.289	C	S	.	.	H	α-helix	trans	-54	-39.3	177	-175.6	-173.3	177.8	0	0	112.1	I91 P92 N101 L225	I91-E95 PolarHBondContact O-N 2.91Å; I91-E95 VanDerWaalsContact O-N 3.12Å; P92-E95 PolarHBondContact O-N 3.37Å; E95-N101 WeakPolarHBondContact O-CB 3.31Å; E95-N101 PolarHBondContact O-ND2 2.92Å; E95-L225 VanDerWaalsContact OE1-CB 3.29Å; E95-L225 WeakPolarHBondContact OE1-CB 3.3Å
96	R	72.9	Confident	82.3	Confident	79 Å²	79	59.3 Å²	59.3	30%	0.298	30%	0.303	S	S	.	.	H	α-helix	trans	-91.3	-15.3	-176.1	-62.7	168.5	179.8	-125	-23.1	113.7	P92 I94 F98 E219 E221 D222	P92-R96 WeakPolarHBondContact O-CD 3.44Å; P92-R96 VanDerWaalsContact O-CG 3.3Å; P92-R96 WeakPolarHBondContact O-CG 3.45Å; P92-R96 PolarHBondContact O-N 3.26Å; I94-R96 PolarHBondContact O-N 2.97Å; R96-F98 PolarHBondContact O-N 2.92Å; R96-E219 IonicContact CZ-OE2 2.84Å; R96-E219 IonicContact NH1-OE2 3.05Å; R96-E219 PolarHBondContact NH1-OE2 2.99Å; R96-E219 IonicContact NH2-OE2 3.84Å; R96-E219 PolarHBondContact NH2-OE2 3.35Å; R96-E221 WeakPolarHBondContact CD-OE2 3.49Å; R96-E221 HydrophobicContact CG-CB 4.11Å; R96-E221 WeakPolarHBondContact CG-OE2 3.34Å; R96-E221 IonicContact CZ-OE2 3.04Å; R96-E221 IonicContact NH1-OE2 2.7Å; R96-D222 IonicContact CZ-OD1 3.97Å; R96-D222 IonicContact NE-OD1 3.72Å; R96-D222 IonicContact NH2-OD1 3.84Å; R96-D222 PolarHBondContact NH2-OD1 3.43Å; R96-D222 IonicContact NH2-OD2 2.68Å
97	F	78.7	Confident	82.7	Confident	134 Å²	134	59.2 Å²	59.2	59%	0.588	30%	0.302	S	S	*	.	S	Bend	trans	-86.1	102.1	-175.3	-161.9	-97.8	0	0	0	111.7	N93 I94 L100 N101	N93-F97 WeakPolarHBondContact O-CB 3.4Å; N93-F97 PolarHBondContact O-N 3.43Å; I94-F97 PolarHBondContact O-N 3.46Å; F97-L100 HydrophobicContact CD1-CB 4.03Å; F97-L100 WeakPolarHBondContact O-CB 3.4Å; F97-L100 PolarHBondContact O-N 3.05Å; F97-N101 PolarHBondContact O-N 3.02Å; F97-N101 PolarHBondContact O-OD1 3.3Å
98	F	80.7	Confident	83.1	Confident	142 Å²	142	57.7 Å²	57.7	62%	0.623	29%	0.294	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.4	136.9	170.5	-178.2	-92.7	0	0	0	110.9	R96 V102	R96-F98 PolarHBondContact O-N 2.92Å; F98-V102 HydrophobicContact CD2-CG2 4.07Å; F98-V102 HydrophobicContact CE2-CG2 4.04Å
99	P	85.2	Confident	83.6	Confident	65 Å²	65	57.6 Å²	57.6	42%	0.422	29%	0.294	S	S	.	.	T	Hydrogen-bonded Turn	cis	-94.5	5.5	4.8	37.2	-36.3	0	0	0	114.7	N101 V102 I103	P99-N101 VanDerWaalsContact C-N 3.3Å; P99-N101 PolarHBondContact O-N 2.9Å; P99-V102 PolarHBondContact O-N 3.04Å; P99-I103 HydrophobicContact CG-CD1 4.45Å; P99-I103 WeakPolarHBondContact O-CG1 3.46Å; P99-I103 PolarHBondContact O-N 2.92Å; P99-I103 VanDerWaalsContact O-N 3.13Å
100	L	86.7	Confident	84.2	Confident	67 Å²	67	60.8 Å²	60.8	35%	0.351	31%	0.31	S	S	.	.	H	α-helix	trans	-59.3	-41.1	-172.6	-176	65	0	0	0	111.9	I94 F97 V102 I103 I104	I94-L100 HydrophobicContact CG1-CD2 4.09Å; I94-L100 HydrophobicContact CG2-CD2 4.02Å; I94-L100 HydrophobicContact CG2-CG 4.24Å; F97-L100 HydrophobicContact CD1-CB 4.03Å; F97-L100 WeakPolarHBondContact O-CB 3.4Å; F97-L100 PolarHBondContact O-N 3.05Å; L100-V102 PolarHBondContact O-N 2.8Å; L100-I103 PolarHBondContact O-N 2.96Å; L100-I104 HydrophobicContact CD1-CD1 3.95Å; L100-I104 HydrophobicContact CD1-CG1 4.24Å; L100-I104 HydrophobicContact CD2-CD1 4.33Å; L100-I104 HydrophobicContact CG-CD1 3.71Å; L100-I104 HydrophobicContact CG-CG1 4.36Å; L100-I104 WeakPolarHBondContact O-CB 3.35Å; L100-I104 VanDerWaalsContact O-CG1 3.27Å; L100-I104 WeakPolarHBondContact O-CG1 3.37Å; L100-I104 PolarHBondContact O-N 3.24Å
101	N	88.2	Confident	85.1	Confident	3 Å²	3	56.8 Å²	56.8	2%	0.016	29%	0.293	C	S	.	.	H	α-helix	trans	-56.1	-45.8	175.5	59.4	-3.9	0	0	0	113.5	I94 E95 F97 P99 I104 L105 V224	I94-N101 WeakPolarHBondContact O-CB 3.39Å; E95-N101 WeakPolarHBondContact O-CB 3.31Å; E95-N101 PolarHBondContact O-ND2 2.92Å; F97-N101 PolarHBondContact O-N 3.02Å; F97-N101 PolarHBondContact O-OD1 3.3Å; P99-N101 VanDerWaalsContact C-N 3.3Å; P99-N101 PolarHBondContact O-N 2.9Å; N101-I104 PolarHBondContact O-N 3.19Å; N101-L105 VanDerWaalsContact O-CB 3.26Å; N101-L105 WeakPolarHBondContact O-CB 3.49Å; N101-L105 PolarHBondContact O-N 3.41Å; N101-V224 HydrophobicContact CB-CG1 4.44Å; N101-V224 HydrophobicContact CB-CG2 4.06Å
102	V	88.5	Confident	86	Confident	49 Å²	49	53.6 Å²	53.6	30%	0.297	28%	0.276	S	S	.	.	H	α-helix	trans	-67.3	-38.1	178.9	177.6	0	0	0	0	111.3	F98 P99 L100 S106	F98-V102 HydrophobicContact CD2-CG2 4.07Å; F98-V102 HydrophobicContact CE2-CG2 4.04Å; P99-V102 PolarHBondContact O-N 3.04Å; L100-V102 PolarHBondContact O-N 2.8Å; V102-S106 WeakPolarHBondContact O-CB 3.49Å; V102-S106 PolarHBondContact O-N 2.96Å; V102-S106 PolarHBondContact O-OG 3.04Å
103	I	90.9	Very high	87.3	Confident	96 Å²	96	50.5 Å²	50.5	49%	0.492	26%	0.257	S	S	.	.	H	α-helix	trans	-63.9	-49.6	177.2	-66.4	168.4	0	0	0	110.2	P99 L100 L105 S106 V107	P99-I103 HydrophobicContact CG-CD1 4.45Å; P99-I103 WeakPolarHBondContact O-CG1 3.46Å; P99-I103 PolarHBondContact O-N 2.92Å; P99-I103 VanDerWaalsContact O-N 3.13Å; L100-I103 PolarHBondContact O-N 2.96Å; I103-L105 VanDerWaalsContact C-N 3.34Å; I103-L105 PolarHBondContact O-N 3.48Å; I103-S106 WeakPolarHBondContact O-CB 3.48Å; I103-S106 PolarHBondContact O-N 3.32Å; I103-S106 VanDerWaalsContact O-N 3.15Å; I103-V107 WeakPolarHBondContact O-CG2 3.32Å; I103-V107 PolarHBondContact O-N 3.24Å
104	I	92.7	Very high	88.3	Confident	25 Å²	25	44.8 Å²	44.8	13%	0.128	23%	0.227	C	C	.	.	H	α-helix	trans	-62.7	-43.1	-179.8	-69.5	175.9	0	0	0	110.5	N84 I87 L88 I94 L100 N101 S106 V107 F108	N84-I104 PolarHBondContact ND2-O 2.84Å; N84-I104 WeakPolarHBondContact OD1-CG2 3.49Å; N84-I104 PolarHBondContact OD1-O 3.23Å; I87-I104 HydrophobicContact CG2-CD1 4.2Å; I87-I104 HydrophobicContact CG2-CG2 4.39Å; L88-I104 HydrophobicContact CD1-CG2 4Å; L88-I104 HydrophobicContact CD2-CB 4.11Å; L88-I104 HydrophobicContact CD2-CG2 3.51Å; L88-I104 HydrophobicContact CG-CG2 3.54Å; I94-I104 HydrophobicContact CG2-CD1 3.32Å; L100-I104 HydrophobicContact CD1-CD1 3.95Å; L100-I104 HydrophobicContact CD1-CG1 4.24Å; L100-I104 HydrophobicContact CD2-CD1 4.33Å; L100-I104 HydrophobicContact CG-CD1 3.71Å; L100-I104 HydrophobicContact CG-CG1 4.36Å; L100-I104 WeakPolarHBondContact O-CB 3.35Å; L100-I104 VanDerWaalsContact O-CG1 3.27Å; L100-I104 WeakPolarHBondContact O-CG1 3.37Å; L100-I104 PolarHBondContact O-N 3.24Å; N101-I104 PolarHBondContact O-N 3.19Å; I104-S106 VanDerWaalsContact C-N 3.33Å; I104-S106 PolarHBondContact O-N 3.41Å; I104-V107 PolarHBondContact O-N 3.45Å; I104-F108 PolarHBondContact O-N 2.95Å
105	L	93.6	Very high	89.3	Confident	4 Å²	4	43 Å²	43	2%	0.021	22%	0.218	C	C	.	.	H	α-helix	trans	-60.1	-41.3	173.4	-173.7	69.2	0	0	0	112.1	V42 Q46 L88 N101 I103 F108 T109 V224 M228	V42-L105 HydrophobicContact CG1-CD2 3.35Å; Q46-L105 VanDerWaalsContact NE2-CD1 3.34Å; L88-L105 HydrophobicContact CD1-CD1 4.17Å; N101-L105 VanDerWaalsContact O-CB 3.26Å; N101-L105 WeakPolarHBondContact O-CB 3.49Å; N101-L105 PolarHBondContact O-N 3.41Å; I103-L105 VanDerWaalsContact C-N 3.34Å; I103-L105 PolarHBondContact O-N 3.48Å; L105-F108 WeakPolarHBondContact O-CB 3.42Å; L105-F108 PolarHBondContact O-N 3.25Å; L105-T109 WeakPolarHBondContact O-CB 3.27Å; L105-T109 PolarHBondContact O-N 3.34Å; L105-T109 PolarHBondContact O-OG1 2.98Å; L105-T109 VanDerWaalsContact O-OG1 3.13Å; L105-V224 HydrophobicContact CB-CG1 4.28Å; L105-V224 HydrophobicContact CD1-CG1 4.25Å; L105-V224 HydrophobicContact CD2-CG1 4.19Å; L105-V224 HydrophobicContact CG-CG1 4.48Å; L105-M228 HydrophobicContact CD1-CB 3.78Å; L105-M228 HydrophobicContact CD1-CG 4.12Å
106	S	94.3	Very high	90.4	Very high	41 Å²	41	43 Å²	43	29%	0.287	22%	0.218	S	C	.	.	H	α-helix	trans	-64.1	-42.6	178.3	-59.8	0	0	0	0	111.4	V102 I103 I104 F108 T109 I110	V102-S106 WeakPolarHBondContact O-CB 3.49Å; V102-S106 PolarHBondContact O-N 2.96Å; V102-S106 PolarHBondContact O-OG 3.04Å; I103-S106 WeakPolarHBondContact O-CB 3.48Å; I103-S106 PolarHBondContact O-N 3.32Å; I103-S106 VanDerWaalsContact O-N 3.15Å; I104-S106 VanDerWaalsContact C-N 3.33Å; I104-S106 PolarHBondContact O-N 3.41Å; S106-F108 VanDerWaalsContact C-N 3.33Å; S106-F108 PolarHBondContact O-N 2.81Å; S106-T109 PolarHBondContact O-N 3.15Å; S106-I110 VanDerWaalsContact O-CG1 3.32Å; S106-I110 WeakPolarHBondContact O-CG1 3.45Å; S106-I110 PolarHBondContact O-N 3.05Å
107	V	95.6	Very high	91.2	Very high	56 Å²	56	39.2 Å²	39.2	34%	0.339	20%	0.204	S	C	.	.	H	α-helix	trans	-62.1	-42.1	174.1	176.3	0	0	0	0	110.8	N84 I103 I104 I110 F111	N84-V107 WeakPolarHBondContact ND2-CG1 3.41Å; I103-V107 WeakPolarHBondContact O-CG2 3.32Å; I103-V107 PolarHBondContact O-N 3.24Å; I104-V107 PolarHBondContact O-N 3.45Å; V107-I110 PolarHBondContact O-N 3.22Å; V107-F111 HydrophobicContact CG1-CD2 3.95Å; V107-F111 HydrophobicContact CG1-CE1 4.43Å; V107-F111 HydrophobicContact CG1-CE2 3.54Å; V107-F111 HydrophobicContact CG1-CZ 3.81Å; V107-F111 WeakPolarHBondContact O-CG 3.21Å; V107-F111 PolarHBondContact O-N 3.3Å
108	F	95.6	Very high	91.7	Very high	0 Å²	0	33 Å²	33	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-59.7	-49.4	175.6	172.5	-93.3	0	0	0	110.5	N81 N84 A85 I104 L105 S106 I110 F111 H112 M228 F231 I232	N81-F108 WeakPolarHBondContact ND2-CE2 3.34Å; N81-F108 WeakPolarHBondContact OD1-CD2 3.27Å; N81-F108 VanDerWaalsContact OD1-CE2 3.31Å; N81-F108 WeakPolarHBondContact OD1-CE2 2.89Å; N81-F108 PolarHBondContact OD1-O 3.15Å; N84-F108 WeakPolarHBondContact ND2-CA 3.41Å; N84-F108 PolarHBondContact ND2-N 3.49Å; A85-F108 HydrophobicContact CB-CD2 4.01Å; A85-F108 HydrophobicContact CB-CE2 3.7Å; I104-F108 PolarHBondContact O-N 2.95Å; L105-F108 WeakPolarHBondContact O-CB 3.42Å; L105-F108 PolarHBondContact O-N 3.25Å; S106-F108 VanDerWaalsContact C-N 3.33Å; S106-F108 PolarHBondContact O-N 2.81Å; F108-I110 VanDerWaalsContact C-N 3.34Å; F108-I110 PolarHBondContact O-N 3.44Å; F108-F111 PolarHBondContact O-N 3.49Å; F108-H112 HydrophobicContact CE1-CB 4.27Å; F108-H112 HydrophobicContact CZ-CB 4.26Å; F108-H112 AromaticContact CZ-ND1 3.77Å; F108-H112 WeakPolarHBondContact O-CB 3.43Å; F108-H112 PolarHBondContact O-N 3.18Å; F108-M228 HydrophobicContact CD1-CG 3.95Å; F108-M228 HydrophobicContact CE1-CG 3.65Å; F108-M228 HydrophobicContact CE1-SD 4.47Å; F108-M228 HydrophobicContact CZ-CG 4.11Å; F108-F231 HydrophobicContact CE1-CD1 4.2Å; F108-I232 HydrophobicContact CE1-CD1 4.22Å; F108-I232 HydrophobicContact CE1-CG1 3.92Å; F108-I232 HydrophobicContact CZ-CD1 3.72Å; F108-I232 HydrophobicContact CZ-CG1 3.6Å
109	T	96.8	Very high	92	Very high	0 Å²	0	26.7 Å²	26.7	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-58.5	-43.4	178.2	-67.2	0	0	0	0	112.2	Q46 I49 L105 S106 S113 F231	Q46-T109 HydrophobicContact CB-CG2 3.82Å; Q46-T109 HydrophobicContact CG-CG2 4.21Å; Q46-T109 WeakPolarHBondContact CG-OG1 3.43Å; Q46-T109 PolarHBondContact NE2-OG1 3.43Å; I49-T109 HydrophobicContact CB-CG2 3.75Å; I49-T109 HydrophobicContact CD1-CG2 4.15Å; I49-T109 HydrophobicContact CG2-CG2 3.67Å; L105-T109 WeakPolarHBondContact O-CB 3.27Å; L105-T109 PolarHBondContact O-N 3.34Å; L105-T109 PolarHBondContact O-OG1 2.98Å; L105-T109 VanDerWaalsContact O-OG1 3.13Å; S106-T109 PolarHBondContact O-N 3.15Å; T109-S113 WeakPolarHBondContact O-CB 3.42Å; T109-S113 PolarHBondContact O-N 3.28Å; T109-S113 PolarHBondContact O-OG 2.9Å; T109-F231 HydrophobicContact CG2-CE1 3.96Å; T109-F231 HydrophobicContact CG2-CE2 4.23Å; T109-F231 HydrophobicContact CG2-CZ 3.63Å
110	I	96	Very high	92	Very high	74 Å²	74	23.7 Å²	23.7	38%	0.379	13%	0.13	S	C	.	.	H	α-helix	trans	-63.5	-49.2	178.4	-67.9	166.1	0	0	0	110.9	I49 S106 V107 F108 S114	I49-I110 HydrophobicContact CG2-CG1 3.67Å; S106-I110 VanDerWaalsContact O-CG1 3.32Å; S106-I110 WeakPolarHBondContact O-CG1 3.45Å; S106-I110 PolarHBondContact O-N 3.05Å; V107-I110 PolarHBondContact O-N 3.22Å; F108-I110 VanDerWaalsContact C-N 3.34Å; F108-I110 PolarHBondContact O-N 3.44Å; I110-S114 VanDerWaalsContact O-CB 3.32Å; I110-S114 WeakPolarHBondContact O-CB 3.45Å; I110-S114 PolarHBondContact O-N 3.35Å; I110-S114 PolarHBondContact O-OG 2.78Å
111	F	95.4	Very high	91.8	Very high	55 Å²	55	24.2 Å²	24.2	24%	0.241	13%	0.127	C	C	.	.	H	α-helix	trans	-65.3	-46.7	-179.5	-68.3	-13.9	0	0	0	111.9	L77 L80 N81 V107 F108 S113 S114 I115	L77-F111 HydrophobicContact CD2-CD1 3.89Å; L77-F111 HydrophobicContact CD2-CE1 4.3Å; L77-F111 HydrophobicContact CD2-CG 4.29Å; L80-F111 HydrophobicContact CB-CD2 3.95Å; L80-F111 HydrophobicContact CB-CE2 3.81Å; L80-F111 HydrophobicContact CD1-CE2 4.23Å; L80-F111 HydrophobicContact CD1-CZ 4.38Å; N81-F111 HydrophobicContact CB-CB 4.09Å; V107-F111 HydrophobicContact CG1-CD2 3.95Å; V107-F111 HydrophobicContact CG1-CE1 4.43Å; V107-F111 HydrophobicContact CG1-CE2 3.54Å; V107-F111 HydrophobicContact CG1-CZ 3.81Å; V107-F111 WeakPolarHBondContact O-CG 3.21Å; V107-F111 PolarHBondContact O-N 3.3Å; F108-F111 PolarHBondContact O-N 3.49Å; F111-S113 PolarHBondContact O-N 3.24Å; F111-S114 PolarHBondContact O-N 3.01Å; F111-I115 WeakPolarHBondContact O-CD1 3.23Å; F111-I115 VanDerWaalsContact O-CG1 3.28Å; F111-I115 WeakPolarHBondContact O-CG1 3.45Å; F111-I115 PolarHBondContact O-N 3.42Å
112	H	95.6	Very high	91.2	Very high	0 Å²	0	27.6 Å²	27.6	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-62.4	-44.1	179.5	-161.7	85.1	0	0	0	111.8	N81 F108 I115 V116 F231 F260 N264	N81-H112 PolarHBondContact ND2-ND1 2.98Å; N81-H112 PolarHBondContact OD1-N 3.37Å; F108-H112 HydrophobicContact CE1-CB 4.27Å; F108-H112 HydrophobicContact CZ-CB 4.26Å; F108-H112 AromaticContact CZ-ND1 3.77Å; F108-H112 WeakPolarHBondContact O-CB 3.43Å; F108-H112 PolarHBondContact O-N 3.18Å; H112-I115 PolarHBondContact O-N 2.99Å; H112-V116 WeakPolarHBondContact O-CG2 3.38Å; H112-V116 PolarHBondContact O-N 3.36Å; H112-V116 VanDerWaalsContact O-N 3.14Å; H112-F231 HydrophobicContact CB-CE1 4.28Å; H112-F231 AromaticContact CD2-CE1 3.93Å; H112-F260 AromaticContact CE1-CE1 3.98Å; H112-F260 AromaticContact CE1-CE2 3.81Å; H112-F260 AromaticContact CE1-CZ 3.18Å; H112-F260 WeakPolarHBondContact CE1-CZ 3.07Å; H112-F260 AromaticContact ND1-CE2 3.77Å; H112-F260 AromaticContact ND1-CZ 3.49Å; H112-F260 WeakPolarHBondContact ND1-CZ 3.39Å; H112-F260 AromaticContact NE2-CZ 3.57Å; H112-N264 PolarHBondContact CE1-OD1 3.46Å
113	S	95.2	Very high	90.6	Very high	0 Å²	0	26.2 Å²	26.2	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-61	-46.3	173.6	-58.4	0	0	0	0	111.2	L50 T109 F111 I115 V116 V117	L50-S113 WeakPolarHBondContact CD1-OG 3.39Å; T109-S113 WeakPolarHBondContact O-CB 3.42Å; T109-S113 PolarHBondContact O-N 3.28Å; T109-S113 PolarHBondContact O-OG 2.9Å; F111-S113 PolarHBondContact O-N 3.24Å; S113-I115 VanDerWaalsContact C-N 3.27Å; S113-I115 PolarHBondContact O-N 3.43Å; S113-V116 PolarHBondContact O-N 3.33Å; S113-V117 WeakPolarHBondContact O-CB 3.15Å; S113-V117 VanDerWaalsContact O-CG2 3.22Å; S113-V117 WeakPolarHBondContact O-CG2 3.45Å; S113-V117 PolarHBondContact O-N 3.46Å
114	S	92.5	Very high	90	Very high	12 Å²	12	22.9 Å²	22.9	8%	0.084	12%	0.124	C	C	.	.	H	α-helix	trans	-59.2	-41.7	-180	-59	0	0	0	0	110.7	I110 F111 N118	I110-S114 VanDerWaalsContact O-CB 3.32Å; I110-S114 WeakPolarHBondContact O-CB 3.45Å; I110-S114 PolarHBondContact O-N 3.35Å; I110-S114 PolarHBondContact O-OG 2.78Å; F111-S114 PolarHBondContact O-N 3.01Å; S114-N118 PolarHBondContact O-N 2.83Å; S114-N118 VanDerWaalsContact O-N 3.11Å; S114-N118 PolarHBondContact O-ND2 3.12Å
115	I	91.9	Very high	89.6	Confident	0 Å²	0	24 Å²	24	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-61.3	-50.3	177.6	-65.2	157.7	0	0	0	110.9	M74 L77 N81 F111 H112 S113 N118 I119 F260	M74-I115 HydrophobicContact CE-CB 4.28Å; M74-I115 HydrophobicContact CE-CG1 4.49Å; M74-I115 HydrophobicContact CE-CG2 3.99Å; M74-I115 WeakPolarHBondContact CE-O 3.33Å; L77-I115 HydrophobicContact CB-CD1 4.13Å; L77-I115 HydrophobicContact CB-CG1 3.81Å; N81-I115 HydrophobicContact CB-CD1 3.91Å; F111-I115 WeakPolarHBondContact O-CD1 3.23Å; F111-I115 VanDerWaalsContact O-CG1 3.28Å; F111-I115 WeakPolarHBondContact O-CG1 3.45Å; F111-I115 PolarHBondContact O-N 3.42Å; H112-I115 PolarHBondContact O-N 2.99Å; S113-I115 VanDerWaalsContact C-N 3.27Å; S113-I115 PolarHBondContact O-N 3.43Å; I115-N118 PolarHBondContact O-N 3.21Å; I115-I119 HydrophobicContact CG2-CD1 3.73Å; I115-I119 VanDerWaalsContact O-CG1 3.31Å; I115-I119 WeakPolarHBondContact O-CG1 3.32Å; I115-I119 PolarHBondContact O-N 3.23Å; I115-I119 VanDerWaalsContact O-N 3.15Å; I115-F260 HydrophobicContact CB-CD2 4.4Å; I115-F260 HydrophobicContact CB-CE2 3.94Å; I115-F260 HydrophobicContact CB-CZ 4.36Å; I115-F260 HydrophobicContact CD1-CD2 4.32Å; I115-F260 HydrophobicContact CD1-CE2 3.83Å; I115-F260 HydrophobicContact CG1-CE2 4.49Å; I115-F260 HydrophobicContact CG2-CD2 3.5Å; I115-F260 HydrophobicContact CG2-CE2 3.5Å; I115-F260 HydrophobicContact CG2-CG 4.03Å; I115-F260 HydrophobicContact CG2-CZ 4.04Å
116	V	92	Very high	89.3	Confident	1 Å²	1	28.7 Å²	28.7	1%	0.006	17%	0.165	C	C	.	.	H	α-helix	trans	-61.6	-48.8	-178.6	175.6	0	0	0	0	110.9	H112 S113 N118 I119 T120 L235 L239 F260	H112-V116 WeakPolarHBondContact O-CG2 3.38Å; H112-V116 PolarHBondContact O-N 3.36Å; H112-V116 VanDerWaalsContact O-N 3.14Å; S113-V116 PolarHBondContact O-N 3.33Å; V116-N118 VanDerWaalsContact C-N 3.31Å; V116-N118 PolarHBondContact O-N 3.46Å; V116-I119 PolarHBondContact O-N 3.17Å; V116-I119 VanDerWaalsContact O-N 3.07Å; V116-T120 HydrophobicContact CG1-CG2 4.12Å; V116-T120 WeakPolarHBondContact O-CG2 3.49Å; V116-T120 PolarHBondContact O-N 3.38Å; V116-T120 PolarHBondContact O-OG1 3.06Å; V116-L235 HydrophobicContact CG1-CD2 4.24Å; V116-L235 HydrophobicContact CG2-CB 4.42Å; V116-L235 HydrophobicContact CG2-CD1 4.5Å; V116-L239 HydrophobicContact CG1-CB 4.44Å; V116-F260 HydrophobicContact CG2-CE1 3.74Å; V116-F260 HydrophobicContact CG2-CZ 3.87Å
117	V	90	Very high	88.9	Confident	0 Å²	0	28.4 Å²	28.4	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-59.7	-40.9	-178.1	176	0	0	0	0	111.7	V53 F54 F57 S113 I119 T120 Y121	V53-V117 HydrophobicContact CG1-CG2 4.06Å; F54-V117 HydrophobicContact CB-CG2 4.43Å; F54-V117 HydrophobicContact CD1-CB 4.39Å; F54-V117 HydrophobicContact CD1-CG1 3.99Å; F54-V117 HydrophobicContact CD1-CG2 3.63Å; F54-V117 HydrophobicContact CD2-CG2 3.63Å; F54-V117 HydrophobicContact CE1-CB 4.35Å; F54-V117 HydrophobicContact CE1-CG1 4.26Å; F54-V117 HydrophobicContact CE1-CG2 3.69Å; F54-V117 HydrophobicContact CE2-CG2 3.69Å; F54-V117 HydrophobicContact CG-CG2 3.61Å; F54-V117 HydrophobicContact CZ-CG2 3.71Å; F57-V117 HydrophobicContact CB-CG1 3.48Å; F57-V117 VanDerWaalsContact CB-CG1 3.48Å; F57-V117 HydrophobicContact CD1-CG1 4.24Å; F57-V117 HydrophobicContact CD2-CG1 4.42Å; F57-V117 HydrophobicContact CG-CG1 3.79Å; S113-V117 WeakPolarHBondContact O-CB 3.15Å; S113-V117 VanDerWaalsContact O-CG2 3.22Å; S113-V117 WeakPolarHBondContact O-CG2 3.45Å; S113-V117 PolarHBondContact O-N 3.46Å; V117-I119 VanDerWaalsContact C-N 3.34Å; V117-I119 PolarHBondContact O-N 3.29Å; V117-T120 PolarHBondContact O-N 2.98Å; V117-Y121 WeakPolarHBondContact O-CA 3Å; V117-Y121 VanDerWaalsContact O-CB 3.27Å; V117-Y121 WeakPolarHBondContact O-CB 3.42Å; V117-Y121 PolarHBondContact O-N 3.24Å
118	N	87.7	Confident	88.5	Confident	3 Å²	3	25.9 Å²	25.9	2%	0.016	15%	0.145	C	C	.	.	H	α-helix	trans	-67.2	-35.4	177	-81.3	-74.9	0	0	0	113	F57 I67 M74 S114 I115 V116	F57-N118 WeakPolarHBondContact CE1-ND2 3.34Å; F57-N118 WeakPolarHBondContact CE1-OD1 3.4Å; I67-N118 WeakPolarHBondContact CD1-OD1 3.45Å; I67-N118 HydrophobicContact CG2-CB 4.5Å; I67-N118 WeakPolarHBondContact CG2-OD1 3.44Å; M74-N118 HydrophobicContact CE-CB 3.5Å; M74-N118 VanDerWaalsContact CE-CB 3.5Å; M74-N118 HydrophobicContact SD-CB 3.58Å; M74-N118 VanDerWaalsContact SD-CB 3.58Å; S114-N118 PolarHBondContact O-N 2.83Å; S114-N118 VanDerWaalsContact O-N 3.11Å; S114-N118 PolarHBondContact O-ND2 3.12Å; I115-N118 PolarHBondContact O-N 3.21Å; V116-N118 VanDerWaalsContact C-N 3.31Å; V116-N118 PolarHBondContact O-N 3.46Å
119	I	87.1	Confident	88.3	Confident	10 Å²	10	28 Å²	28	5%	0.051	16%	0.163	C	C	.	.	H	α-helix	trans	-69.1	-42.2	176.8	-66.6	164.8	0	0	0	109.8	M74 I115 V116 V117 L239 L256 K257	M74-I119 HydrophobicContact CE-CG1 4.25Å; I115-I119 HydrophobicContact CG2-CD1 3.73Å; I115-I119 VanDerWaalsContact O-CG1 3.31Å; I115-I119 WeakPolarHBondContact O-CG1 3.32Å; I115-I119 PolarHBondContact O-N 3.23Å; I115-I119 VanDerWaalsContact O-N 3.15Å; V116-I119 PolarHBondContact O-N 3.17Å; V116-I119 VanDerWaalsContact O-N 3.07Å; V117-I119 VanDerWaalsContact C-N 3.34Å; V117-I119 PolarHBondContact O-N 3.29Å; I119-L239 HydrophobicContact CB-CD1 4.24Å; I119-L239 HydrophobicContact CD1-CD2 4.49Å; I119-L239 HydrophobicContact CG2-CD1 3.65Å; I119-L256 HydrophobicContact CD1-CD2 4.34Å; I119-L256 HydrophobicContact CD1-CG 4.35Å; I119-L256 HydrophobicContact CG1-CD2 4.04Å; I119-L256 HydrophobicContact CG1-CG 4.48Å; I119-K257 HydrophobicContact CG2-CB 3.96Å; I119-K257 HydrophobicContact CG2-CD 4.18Å; I119-K257 HydrophobicContact CG2-CG 4.26Å
120	T	86.2	Confident	88	Confident	2 Å²	2	31.6 Å²	31.6	1%	0.012	18%	0.181	C	C	.	.	H	α-helix	trans	-89.3	-12.7	-173	67.2	0	0	0	0	114.1	V116 V117 Q122 N123 D128 L239	V116-T120 HydrophobicContact CG1-CG2 4.12Å; V116-T120 WeakPolarHBondContact O-CG2 3.49Å; V116-T120 PolarHBondContact O-N 3.38Å; V116-T120 PolarHBondContact O-OG1 3.06Å; V117-T120 PolarHBondContact O-N 2.98Å; T120-Q122 PolarHBondContact O-N 2.91Å; T120-N123 VanDerWaalsContact O-CB 3.32Å; T120-N123 WeakPolarHBondContact O-CB 3.29Å; T120-N123 PolarHBondContact O-N 3.19Å; T120-D128 VanDerWaalsContact CB-CG 3.46Å; T120-D128 VanDerWaalsContact CB-OD1 3.3Å; T120-D128 WeakPolarHBondContact CB-OD1 3.33Å; T120-D128 WeakPolarHBondContact CB-OD2 3.19Å; T120-D128 PolarHBondContact OG1-OD2 3.2Å; T120-L239 HydrophobicContact CG2-CD1 3.47Å; T120-L239 VanDerWaalsContact CG2-CD1 3.47Å
121	Y	82.2	Confident	87.8	Confident	78 Å²	78	28 Å²	28	31%	0.306	16%	0.163	S	C	.	.	G	3₁₀ helix	trans	-47	-36.3	-177.3	179.8	-109.6	0	0	0	113.8	Y58 N64 V117 N123 G124	Y58-Y121 AromaticContact CD1-CD2 3.89Å; Y58-Y121 HydrophobicContact CD1-CD2 3.89Å; Y58-Y121 AromaticContact CD1-CE2 3.57Å; Y58-Y121 HydrophobicContact CD1-CE2 3.57Å; Y58-Y121 AromaticContact CE1-CD2 3.52Å; Y58-Y121 HydrophobicContact CE1-CD2 3.52Å; Y58-Y121 AromaticContact CE1-CE2 3.56Å; Y58-Y121 HydrophobicContact CE1-CE2 3.56Å; Y58-Y121 HydrophobicContact CG-CD2 4.49Å; Y58-Y121 HydrophobicContact CG-CE2 4.34Å; Y58-Y121 AromaticContact CZ-CD2 3.87Å; Y58-Y121 PolarHBondContact OH-O 2.73Å; N64-Y121 HydrophobicContact CB-CD1 4.3Å; N64-Y121 HydrophobicContact CB-CE1 3.95Å; N64-Y121 WeakPolarHBondContact ND2-CD2 3.47Å; N64-Y121 WeakPolarHBondContact ND2-CE2 3.34Å; V117-Y121 WeakPolarHBondContact O-CA 3Å; V117-Y121 VanDerWaalsContact O-CB 3.27Å; V117-Y121 WeakPolarHBondContact O-CB 3.42Å; V117-Y121 PolarHBondContact O-N 3.24Å; Y121-N123 PolarHBondContact O-N 3.33Å; Y121-G124 PolarHBondContact O-N 2.85Å
122	Q	75.7	Confident	87.7	Confident	73 Å²	73	26.4 Å²	26.4	34%	0.341	16%	0.156	S	C	.	.	G	3₁₀ helix	trans	-70.1	-25.5	-179.3	-63.3	-179.2	4.5	0	0	114.3	T120 G124 I250 Y253	T120-Q122 PolarHBondContact O-N 2.91Å; Q122-G124 PolarHBondContact O-N 3.29Å; Q122-I250 VanDerWaalsContact NE2-CD1 3.25Å; Q122-Y253 VanDerWaalsContact NE2-CD2 3.33Å
123	N	75.9	Confident	87.7	Confident	20 Å²	20	30.8 Å²	30.8	11%	0.107	18%	0.178	C	C	.	.	G	3₁₀ helix	trans	-67.7	-25.8	175.5	-58.4	-29.8	0	0	0	111.6	T120 Y121 D127 D128 E246	T120-N123 VanDerWaalsContact O-CB 3.32Å; T120-N123 WeakPolarHBondContact O-CB 3.29Å; T120-N123 PolarHBondContact O-N 3.19Å; Y121-N123 PolarHBondContact O-N 3.33Å; N123-D127 HydrophobicContact CB-CB 4.4Å; N123-D128 WeakPolarHBondContact CB-OD1 3.36Å; N123-D128 PolarHBondContact ND2-OD1 3.23Å; N123-E246 WeakPolarHBondContact OD1-CA 3.44Å; N123-E246 VanDerWaalsContact OD1-CB 3.3Å; N123-E246 WeakPolarHBondContact OD1-CB 3.28Å; N123-E246 WeakPolarHBondContact OD1-CG 3.18Å
124	G	79.1	Confident	87.6	Confident	27 Å²	27	34 Å²	34	28%	0.278	20%	0.195	S	C	.	.			trans	92.4	149.6	-175.5	0	0	0	0	0	112.9	Y121 Q122 V126 D127 D128	Y121-G124 PolarHBondContact O-N 2.85Å; Q122-G124 PolarHBondContact O-N 3.29Å; G124-V126 PolarHBondContact O-N 3.06Å; G124-V126 VanDerWaalsContact O-N 3.14Å; G124-D127 PolarHBondContact O-N 3.48Å; G124-D128 PolarHBondContact O-N 2.97Å
125	A	82.4	Confident	87.8	Confident	49 Å²	49	33.5 Å²	33.5	41%	0.405	19%	0.191	S	C	.	.	H	α-helix	trans	-60.1	-32.8	-168.4	0	0	0	0	0	113.9	Y58 A129	Y58-A125 HydrophobicContact CD1-CB 3.94Å; Y58-A125 HydrophobicContact CD2-CB 4.16Å; Y58-A125 HydrophobicContact CE1-CB 3.63Å; Y58-A125 HydrophobicContact CE2-CB 3.82Å; Y58-A125 HydrophobicContact CG-CB 4.22Å; Y58-A125 WeakPolarHBondContact OH-CA 3.33Å; Y58-A125 PolarHBondContact OH-N 3.02Å; Y58-A125 VanDerWaalsContact OH-N 3.12Å; A125-A129 VanDerWaalsContact O-CB 3.26Å; A125-A129 WeakPolarHBondContact O-CB 3.16Å; A125-A129 PolarHBondContact O-N 3.28Å
126	V	87.4	Confident	87.9	Confident	101 Å²	101	35.3 Å²	35.3	61%	0.612	20%	0.201	S	C	*	.	H	α-helix	trans	-70.8	-44.1	-177.9	178.3	0	0	0	0	110.7	G124 A129 I130	G124-V126 PolarHBondContact O-N 3.06Å; G124-V126 VanDerWaalsContact O-N 3.14Å; V126-A129 PolarHBondContact O-N 2.98Å; V126-I130 HydrophobicContact CG1-CD1 3.75Å; V126-I130 HydrophobicContact CG1-CG1 4.43Å; V126-I130 WeakPolarHBondContact O-CB 3.38Å; V126-I130 VanDerWaalsContact O-CG1 3.23Å; V126-I130 WeakPolarHBondContact O-CG1 3.27Å; V126-I130 PolarHBondContact O-N 3.33Å
127	D	87.3	Confident	88	Confident	36 Å²	36	39.9 Å²	39.9	19%	0.193	22%	0.224	C	C	.	.	H	α-helix	trans	-69	-39	-177.4	-69.4	-9.5	0	0	0	110.7	N123 G124 I130 S131 F245	N123-D127 HydrophobicContact CB-CB 4.4Å; G124-D127 PolarHBondContact O-N 3.48Å; D127-I130 PolarHBondContact O-N 3.46Å; D127-S131 WeakPolarHBondContact O-CB 3.41Å; D127-S131 PolarHBondContact O-N 3.46Å; D127-F245 HydrophobicContact CB-CB 3.79Å; D127-F245 HydrophobicContact CB-CD2 4.32Å; D127-F245 HydrophobicContact CB-CG 4.14Å
128	D	87.1	Confident	88.2	Confident	2 Å²	2	42 Å²	42	1%	0.011	24%	0.237	C	C	.	.	H	α-helix	trans	-64.8	-42.2	173.3	-74.4	-2.8	0	0	0	112.4	F54 Y58 T120 N123 G124 S131 F132	F54-D128 HydrophobicContact CE1-CB 4.13Å; Y58-D128 PolarHBondContact OH-OD2 3.26Å; T120-D128 VanDerWaalsContact CB-CG 3.46Å; T120-D128 VanDerWaalsContact CB-OD1 3.3Å; T120-D128 WeakPolarHBondContact CB-OD1 3.33Å; T120-D128 WeakPolarHBondContact CB-OD2 3.19Å; T120-D128 PolarHBondContact OG1-OD2 3.2Å; N123-D128 WeakPolarHBondContact CB-OD1 3.36Å; N123-D128 PolarHBondContact ND2-OD1 3.23Å; G124-D128 PolarHBondContact O-N 2.97Å; D128-S131 PolarHBondContact O-N 2.85Å; D128-S131 PolarHBondContact O-OG 2.88Å; D128-F132 VanDerWaalsContact O-CB 3.32Å; D128-F132 WeakPolarHBondContact O-CB 3.47Å; D128-F132 PolarHBondContact O-N 3.41Å
129	A	89.9	Confident	88.4	Confident	46 Å²	46	42 Å²	42	38%	0.38	24%	0.238	S	C	.	.	H	α-helix	trans	-64.8	-43.4	176.7	0	0	0	0	0	111.5	A125 V126 F132 I133	A125-A129 VanDerWaalsContact O-CB 3.26Å; A125-A129 WeakPolarHBondContact O-CB 3.16Å; A125-A129 PolarHBondContact O-N 3.28Å; V126-A129 PolarHBondContact O-N 2.98Å; A129-F132 PolarHBondContact O-N 2.92Å; A129-I133 WeakPolarHBondContact O-CB 3.47Å; A129-I133 WeakPolarHBondContact O-CD1 3.17Å; A129-I133 WeakPolarHBondContact O-CG1 3.41Å; A129-I133 PolarHBondContact O-N 3.19Å
130	I	92.3	Very high	88.5	Confident	74 Å²	74	45 Å²	45	38%	0.379	25%	0.252	S	S	.	.	H	α-helix	trans	-62	-47.2	177.3	-71.3	168.1	0	0	0	110.2	V126 D127 F132 I133 I134 F245	V126-I130 HydrophobicContact CG1-CD1 3.75Å; V126-I130 HydrophobicContact CG1-CG1 4.43Å; V126-I130 WeakPolarHBondContact O-CB 3.38Å; V126-I130 VanDerWaalsContact O-CG1 3.23Å; V126-I130 WeakPolarHBondContact O-CG1 3.27Å; V126-I130 PolarHBondContact O-N 3.33Å; D127-I130 PolarHBondContact O-N 3.46Å; I130-F132 VanDerWaalsContact C-N 3.33Å; I130-F132 PolarHBondContact O-N 2.92Å; I130-I133 PolarHBondContact O-N 3.38Å; I130-I134 HydrophobicContact CG2-CD1 3.71Å; I130-I134 HydrophobicContact CG2-CG1 4.45Å; I130-I134 VanDerWaalsContact O-CG1 3.27Å; I130-I134 WeakPolarHBondContact O-CG1 3.28Å; I130-I134 PolarHBondContact O-N 2.95Å; I130-F245 HydrophobicContact CG2-CZ 4.33Å
131	S	91.7	Very high	88.7	Confident	0 Å²	0	49.3 Å²	49.3	0%	0	27%	0.274	C	S	.	.	H	α-helix	trans	-60.1	-45.6	179.8	84.1	0	0	0	0	110.9	D127 D128 I133 I134 V135 S238 S242	D127-S131 WeakPolarHBondContact O-CB 3.41Å; D127-S131 PolarHBondContact O-N 3.46Å; D128-S131 PolarHBondContact O-N 2.85Å; D128-S131 PolarHBondContact O-OG 2.88Å; S131-I133 PolarHBondContact O-N 3.46Å; S131-I134 PolarHBondContact O-N 3.33Å; S131-V135 WeakPolarHBondContact O-CG2 3.26Å; S131-V135 PolarHBondContact O-N 3Å; S131-S238 PolarHBondContact OG-OG 3.26Å; S131-S242 WeakPolarHBondContact CB-OG 3.47Å; S131-S242 PolarHBondContact OG-OG 3.21Å
132	F	93.4	Very high	89	Confident	20 Å²	20	47.5 Å²	47.5	9%	0.088	27%	0.27	C	S	.	.	H	α-helix	trans	-64.7	-42.2	-179.5	-172.3	-108.2	0	0	0	111.9	V47 L50 D128 A129 I130 V135 L136 I234 L235	V47-F132 HydrophobicContact CG1-CE1 4.05Å; V47-F132 HydrophobicContact CG1-CZ 4.04Å; V47-F132 HydrophobicContact CG2-CZ 4.34Å; L50-F132 HydrophobicContact CD2-CD2 4.28Å; L50-F132 HydrophobicContact CD2-CE1 4.23Å; L50-F132 HydrophobicContact CD2-CE2 3.48Å; L50-F132 VanDerWaalsContact CD2-CE2 3.48Å; L50-F132 HydrophobicContact CD2-CZ 3.46Å; L50-F132 VanDerWaalsContact CD2-CZ 3.46Å; D128-F132 VanDerWaalsContact O-CB 3.32Å; D128-F132 WeakPolarHBondContact O-CB 3.47Å; D128-F132 PolarHBondContact O-N 3.41Å; A129-F132 PolarHBondContact O-N 2.92Å; I130-F132 VanDerWaalsContact C-N 3.33Å; I130-F132 PolarHBondContact O-N 2.92Å; F132-V135 PolarHBondContact O-N 3.28Å; F132-L136 HydrophobicContact CD1-CD1 3.76Å; F132-L136 HydrophobicContact CD1-CG 4.22Å; F132-L136 HydrophobicContact CE1-CD1 3.31Å; F132-L136 HydrophobicContact CE1-CD2 4.44Å; F132-L136 HydrophobicContact CE1-CG 3.89Å; F132-L136 HydrophobicContact CE2-CG 4.48Å; F132-L136 HydrophobicContact CZ-CD1 3.84Å; F132-L136 HydrophobicContact CZ-CD2 4.14Å; F132-L136 HydrophobicContact CZ-CG 4.01Å; F132-L136 WeakPolarHBondContact O-CB 3.45Å; F132-L136 WeakPolarHBondContact O-CG 3.5Å; F132-L136 PolarHBondContact O-N 3.5Å; F132-I234 HydrophobicContact CE2-CG2 3.85Å; F132-I234 HydrophobicContact CZ-CG2 4.44Å; F132-L235 HydrophobicContact CD2-CD2 4.43Å; F132-L235 HydrophobicContact CE2-CD2 4.1Å
133	I	94	Very high	89.4	Confident	93 Å²	93	46 Å²	46	48%	0.477	26%	0.262	S	S	.	.	H	α-helix	trans	-62.3	-45.4	176	-71.2	166.3	0	0	0	111.1	A129 I130 S131 V135 L136 I137	A129-I133 WeakPolarHBondContact O-CB 3.47Å; A129-I133 WeakPolarHBondContact O-CD1 3.17Å; A129-I133 WeakPolarHBondContact O-CG1 3.41Å; A129-I133 PolarHBondContact O-N 3.19Å; I130-I133 PolarHBondContact O-N 3.38Å; S131-I133 PolarHBondContact O-N 3.46Å; I133-V135 VanDerWaalsContact C-N 3.31Å; I133-V135 PolarHBondContact O-N 3.43Å; I133-L136 PolarHBondContact O-N 2.8Å; I133-I137 HydrophobicContact CG2-CD1 3.69Å; I133-I137 HydrophobicContact CG2-CG1 4.39Å; I133-I137 VanDerWaalsContact O-CG1 3.31Å; I133-I137 WeakPolarHBondContact O-CG1 3.2Å; I133-I137 PolarHBondContact O-N 2.87Å
134	I	94.6	Very high	89.8	Confident	68 Å²	68	49.3 Å²	49.3	35%	0.349	28%	0.283	S	S	.	.	H	α-helix	trans	-59.2	-46	177.5	-68.8	165.5	0	0	0	110.2	I130 S131 I137 T138 L241	I130-I134 HydrophobicContact CG2-CD1 3.71Å; I130-I134 HydrophobicContact CG2-CG1 4.45Å; I130-I134 VanDerWaalsContact O-CG1 3.27Å; I130-I134 WeakPolarHBondContact O-CG1 3.28Å; I130-I134 PolarHBondContact O-N 2.95Å; S131-I134 PolarHBondContact O-N 3.33Å; I134-I137 PolarHBondContact O-N 3.31Å; I134-T138 HydrophobicContact CG2-CG2 4.39Å; I134-T138 WeakPolarHBondContact O-CB 3.43Å; I134-T138 WeakPolarHBondContact O-CG2 3.4Å; I134-T138 PolarHBondContact O-N 3.32Å; I134-T138 PolarHBondContact O-OG1 3.4Å; I134-L241 HydrophobicContact CB-CD2 3.79Å; I134-L241 HydrophobicContact CD1-CD2 4.25Å; I134-L241 HydrophobicContact CG2-CD2 3.63Å
135	V	95	Very high	90.1	Very high	0 Å²	0	51.9 Å²	51.9	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-64.7	-41.8	179.4	174.2	0	0	0	0	111.6	S131 F132 I133 T138 S139 F196 I234 L241	S131-V135 WeakPolarHBondContact O-CG2 3.26Å; S131-V135 PolarHBondContact O-N 3Å; F132-V135 PolarHBondContact O-N 3.28Å; I133-V135 VanDerWaalsContact C-N 3.31Å; I133-V135 PolarHBondContact O-N 3.43Å; V135-T138 WeakPolarHBondContact CA-OG1 3.43Å; V135-T138 PolarHBondContact O-OG1 3.33Å; V135-T138 VanDerWaalsContact O-OG1 3.05Å; V135-S139 WeakPolarHBondContact O-CB 3.45Å; V135-S139 PolarHBondContact O-N 3.05Å; V135-S139 PolarHBondContact O-OG 3.39Å; V135-F196 HydrophobicContact CG2-CD2 4.34Å; V135-F196 HydrophobicContact CG2-CE2 3.72Å; V135-I234 HydrophobicContact CG1-CG2 4.12Å; V135-I234 WeakPolarHBondContact CG1-O 3.43Å; V135-L241 HydrophobicContact CG2-CB 4.27Å; V135-L241 HydrophobicContact CG2-CD2 3.87Å
136	L	93.8	Very high	90.1	Very high	39 Å²	39	50 Å²	50	20%	0.204	27%	0.273	C	S	.	.	H	α-helix	trans	-62.2	-47.2	176.3	-78.9	-178.2	0	0	0	111.6	F43 F132 I133 M140 I234	F43-L136 HydrophobicContact CE1-CD2 4.46Å; F43-L136 HydrophobicContact CZ-CD2 4.01Å; F132-L136 HydrophobicContact CD1-CD1 3.76Å; F132-L136 HydrophobicContact CD1-CG 4.22Å; F132-L136 HydrophobicContact CE1-CD1 3.31Å; F132-L136 HydrophobicContact CE1-CD2 4.44Å; F132-L136 HydrophobicContact CE1-CG 3.89Å; F132-L136 HydrophobicContact CE2-CG 4.48Å; F132-L136 HydrophobicContact CZ-CD1 3.84Å; F132-L136 HydrophobicContact CZ-CD2 4.14Å; F132-L136 HydrophobicContact CZ-CG 4.01Å; F132-L136 WeakPolarHBondContact O-CB 3.45Å; F132-L136 WeakPolarHBondContact O-CG 3.5Å; F132-L136 PolarHBondContact O-N 3.5Å; I133-L136 PolarHBondContact O-N 2.8Å; L136-M140 VanDerWaalsContact O-CB 3.22Å; L136-M140 WeakPolarHBondContact O-CB 3.4Å; L136-M140 WeakPolarHBondContact O-CG 3.4Å; L136-M140 PolarHBondContact O-N 3.41Å; L136-I234 HydrophobicContact CD2-CD1 4.25Å; L136-I234 HydrophobicContact CD2-CG2 3.84Å
137	I	94.6	Very high	89.6	Confident	96 Å²	96	47.7 Å²	47.7	49%	0.492	26%	0.259	S	S	.	.	H	α-helix	trans	-62.9	-49.4	-179.7	-68.6	169.4	0	0	0	110.4	I133 I134 M140 I141	I133-I137 HydrophobicContact CG2-CD1 3.69Å; I133-I137 HydrophobicContact CG2-CG1 4.39Å; I133-I137 VanDerWaalsContact O-CG1 3.31Å; I133-I137 WeakPolarHBondContact O-CG1 3.2Å; I133-I137 PolarHBondContact O-N 2.87Å; I134-I137 PolarHBondContact O-N 3.31Å; I137-M140 PolarHBondContact O-N 3.02Å; I137-I141 HydrophobicContact CG2-CD1 3.79Å; I137-I141 VanDerWaalsContact O-CG1 3.26Å; I137-I141 WeakPolarHBondContact O-CG1 3.3Å; I137-I141 PolarHBondContact O-N 2.86Å
138	T	93.8	Very high	89	Confident	45 Å²	45	53 Å²	53	28%	0.276	28%	0.281	S	S	.	.	H	α-helix	trans	-62.1	-46	179.8	48.5	0	0	0	0	111.7	I134 V135 M140 I141 L142	I134-T138 HydrophobicContact CG2-CG2 4.39Å; I134-T138 WeakPolarHBondContact O-CB 3.43Å; I134-T138 WeakPolarHBondContact O-CG2 3.4Å; I134-T138 PolarHBondContact O-N 3.32Å; I134-T138 PolarHBondContact O-OG1 3.4Å; V135-T138 WeakPolarHBondContact CA-OG1 3.43Å; V135-T138 PolarHBondContact O-OG1 3.33Å; V135-T138 VanDerWaalsContact O-OG1 3.05Å; T138-M140 PolarHBondContact O-N 2.99Å; T138-I141 PolarHBondContact O-N 3.34Å; T138-L142 WeakPolarHBondContact O-CG 3.47Å; T138-L142 PolarHBondContact O-N 3.22Å
139	S	92.3	Very high	88.2	Confident	4 Å²	4	58.8 Å²	58.8	3%	0.028	30%	0.303	C	S	.	.	H	α-helix	trans	-64.8	-37.9	178.2	-55.4	0	0	0	0	112.1	V135 L142 F143 Q200	V135-S139 WeakPolarHBondContact O-CB 3.45Å; V135-S139 PolarHBondContact O-N 3.05Å; V135-S139 PolarHBondContact O-OG 3.39Å; S139-L142 PolarHBondContact O-N 2.95Å; S139-F143 WeakPolarHBondContact O-CB 3.19Å; S139-F143 PolarHBondContact O-N 2.88Å; S139-Q200 PolarHBondContact OG-NE2 3.07Å
140	M	89	Confident	87	Confident	71 Å²	71	60.5 Å²	60.5	35%	0.35	31%	0.312	S	S	.	.	H	α-helix	trans	-66.6	-40.9	175.3	-76.8	-72.5	173.5	0	0	112.3	L40 F43 L136 I137 T138 L142 F143 V144	L40-M140 HydrophobicContact CD1-CE 4.12Å; F43-M140 HydrophobicContact CE1-CE 4.12Å; L136-M140 VanDerWaalsContact O-CB 3.22Å; L136-M140 WeakPolarHBondContact O-CB 3.4Å; L136-M140 WeakPolarHBondContact O-CG 3.4Å; L136-M140 PolarHBondContact O-N 3.41Å; I137-M140 PolarHBondContact O-N 3.02Å; T138-M140 PolarHBondContact O-N 2.99Å; M140-L142 VanDerWaalsContact C-N 3.34Å; M140-F143 WeakPolarHBondContact O-CB 3.34Å; M140-F143 PolarHBondContact O-N 3.4Å; M140-V144 WeakPolarHBondContact O-CG2 3.24Å; M140-V144 PolarHBondContact O-N 3.44Å
141	I	90.6	Very high	85.6	Confident	93 Å²	93	64.2 Å²	64.2	48%	0.477	32%	0.322	S	S	.	.	H	α-helix	trans	-60.9	-47.1	174.1	-69.2	164.7	0	0	0	109.8	I137 T138 F143 V144 I145	I137-I141 HydrophobicContact CG2-CD1 3.79Å; I137-I141 VanDerWaalsContact O-CG1 3.26Å; I137-I141 WeakPolarHBondContact O-CG1 3.3Å; I137-I141 PolarHBondContact O-N 2.86Å; T138-I141 PolarHBondContact O-N 3.34Å; I141-F143 VanDerWaalsContact C-N 3.32Å; I141-F143 PolarHBondContact O-N 3.11Å; I141-V144 PolarHBondContact O-N 2.84Å; I141-I145 HydrophobicContact CG2-CD1 3.68Å; I141-I145 HydrophobicContact CG2-CG1 4.38Å; I141-I145 VanDerWaalsContact O-CG1 3.3Å; I141-I145 WeakPolarHBondContact O-CG1 3.41Å; I141-I145 PolarHBondContact O-N 2.94Å
142	L	88.9	Confident	84.3	Confident	41 Å²	41	68.8 Å²	68.8	22%	0.215	35%	0.347	C	S	.	.	H	α-helix	trans	-61.3	-40.4	176.2	-70.2	178.8	0	0	0	112	T138 S139 M140 V144 I145 T146 Q200 T203 I204	T138-L142 WeakPolarHBondContact O-CG 3.47Å; T138-L142 PolarHBondContact O-N 3.22Å; S139-L142 PolarHBondContact O-N 2.95Å; M140-L142 VanDerWaalsContact C-N 3.34Å; L142-V144 PolarHBondContact O-N 3.2Å; L142-I145 PolarHBondContact O-N 3.3Å; L142-T146 VanDerWaalsContact O-CB 3.25Å; L142-T146 WeakPolarHBondContact O-CB 3.37Å; L142-T146 PolarHBondContact O-N 2.9Å; L142-T146 PolarHBondContact O-OG1 3.29Å; L142-Q200 HydrophobicContact CD1-CB 3.95Å; L142-Q200 VanDerWaalsContact CD1-OE1 3.23Å; L142-T203 HydrophobicContact CB-CG2 4.4Å; L142-I204 HydrophobicContact CB-CG1 4.31Å; L142-I204 HydrophobicContact CD1-CD1 4.41Å; L142-I204 HydrophobicContact CD1-CG1 4.18Å; L142-I204 HydrophobicContact CD2-CD1 4.11Å; L142-I204 HydrophobicContact CD2-CG1 4.24Å; L142-I204 HydrophobicContact CG-CG1 4.49Å
143	F	85	Confident	82.9	Confident	40 Å²	40	71.3 Å²	71.3	18%	0.175	36%	0.361	C	S	.	.	H	α-helix	trans	-58.4	-48.3	175.3	-172.9	-79.2	0	0	0	111.6	Y36 S139 M140 I141 T147 V207 M230	Y36-F143 HydrophobicContact CD1-CZ 4.23Å; S139-F143 WeakPolarHBondContact O-CB 3.19Å; S139-F143 PolarHBondContact O-N 2.88Å; M140-F143 WeakPolarHBondContact O-CB 3.34Å; M140-F143 PolarHBondContact O-N 3.4Å; I141-F143 VanDerWaalsContact C-N 3.32Å; I141-F143 PolarHBondContact O-N 3.11Å; F143-T147 VanDerWaalsContact O-CB 3.3Å; F143-T147 WeakPolarHBondContact O-CB 3.46Å; F143-T147 PolarHBondContact O-N 3.4Å; F143-T147 PolarHBondContact O-OG1 2.9Å; F143-V207 HydrophobicContact CB-CG2 4.23Å; F143-V207 HydrophobicContact CD2-CB 4.28Å; F143-V207 HydrophobicContact CD2-CG1 4.1Å; F143-V207 HydrophobicContact CD2-CG2 3.16Å; F143-V207 HydrophobicContact CE2-CB 4.49Å; F143-V207 HydrophobicContact CE2-CG1 4.14Å; F143-V207 HydrophobicContact CE2-CG2 3.65Å; F143-V207 HydrophobicContact CG-CG1 4.49Å; F143-V207 HydrophobicContact CG-CG2 3.97Å; F143-M230 HydrophobicContact CD2-CE 3.39Å; F143-M230 HydrophobicContact CE2-CE 3.46Å; F143-M230 VanDerWaalsContact CE2-CE 3.46Å
144	V	84.4	Confident	81.5	Confident	91 Å²	91	67.9 Å²	67.9	55%	0.552	34%	0.344	S	S	*	.	H	α-helix	trans	-65.1	-45.4	179.6	171.6	0	0	0	0	111.5	M140 I141 L142 T147 K148	M140-V144 WeakPolarHBondContact O-CG2 3.24Å; M140-V144 PolarHBondContact O-N 3.44Å; I141-V144 PolarHBondContact O-N 2.84Å; L142-V144 PolarHBondContact O-N 3.2Å; V144-T147 PolarHBondContact O-N 3.38Å; V144-K148 VanDerWaalsContact O-CB 3.31Å; V144-K148 WeakPolarHBondContact O-CB 3.41Å; V144-K148 PolarHBondContact O-N 2.89Å
145	I	84.6	Confident	80.1	Confident	80 Å²	80	69.3 Å²	69.3	41%	0.41	36%	0.355	S	S	.	.	H	α-helix	trans	-61.4	-49.8	178.5	-69.1	170.8	0	0	0	110	I141 L142 T147 K148 Y149	I141-I145 HydrophobicContact CG2-CD1 3.68Å; I141-I145 HydrophobicContact CG2-CG1 4.38Å; I141-I145 VanDerWaalsContact O-CG1 3.3Å; I141-I145 WeakPolarHBondContact O-CG1 3.41Å; I141-I145 PolarHBondContact O-N 2.94Å; L142-I145 PolarHBondContact O-N 3.3Å; I145-T147 VanDerWaalsContact C-N 3.29Å; I145-T147 PolarHBondContact O-N 3.28Å; I145-K148 PolarHBondContact O-N 3.14Å; I145-K148 VanDerWaalsContact O-N 3.14Å; I145-Y149 HydrophobicContact CG2-CD2 3.82Å; I145-Y149 HydrophobicContact CG2-CE2 4.23Å; I145-Y149 VanDerWaalsContact O-CD2 3.3Å; I145-Y149 WeakPolarHBondContact O-CD2 3.31Å; I145-Y149 PolarHBondContact O-N 3.1Å
146	T	82.8	Confident	78.6	Confident	11 Å²	11	74.1 Å²	74.1	7%	0.067	38%	0.377	C	S	.	.	H	α-helix	trans	-62.1	-39.3	-178.5	-52.2	0	0	0	0	111	L142 S150 I204 V207 Q208 Q211	L142-T146 VanDerWaalsContact O-CB 3.25Å; L142-T146 WeakPolarHBondContact O-CB 3.37Å; L142-T146 PolarHBondContact O-N 2.9Å; L142-T146 PolarHBondContact O-OG1 3.29Å; T146-S150 PolarHBondContact O-N 2.86Å; T146-I204 HydrophobicContact CG2-CG2 4.13Å; T146-V207 HydrophobicContact CG2-CB 4.03Å; T146-V207 HydrophobicContact CG2-CG1 3.73Å; T146-Q208 HydrophobicContact CG2-CG 3.64Å; T146-Q211 PolarHBondContact O-NE2 3.4Å
147	T	75.7	Confident	77.2	Confident	52 Å²	52	72.7 Å²	72.7	32%	0.319	37%	0.369	S	S	.	.	H	α-helix	trans	-70.6	-29.2	176.5	-52.1	0	0	0	0	113.8	F143 V144 I145 Q211	F143-T147 VanDerWaalsContact O-CB 3.3Å; F143-T147 WeakPolarHBondContact O-CB 3.46Å; F143-T147 PolarHBondContact O-N 3.4Å; F143-T147 PolarHBondContact O-OG1 2.9Å; V144-T147 PolarHBondContact O-N 3.38Å; I145-T147 VanDerWaalsContact C-N 3.29Å; I145-T147 PolarHBondContact O-N 3.28Å; T147-Q211 PolarHBondContact OG1-NE2 3.28Å
148	K	75.5	Confident	75.8	Confident	148 Å²	148	70.5 Å²	70.5	64%	0.643	36%	0.355	S	S	*	.	H	α-helix	trans	-80.2	-42.2	179.5	-176.7	176.6	179.5	-177.6	0	113	V144 I145	V144-K148 VanDerWaalsContact O-CB 3.31Å; V144-K148 WeakPolarHBondContact O-CB 3.41Å; V144-K148 PolarHBondContact O-N 2.89Å; I145-K148 PolarHBondContact O-N 3.14Å; I145-K148 VanDerWaalsContact O-N 3.14Å
149	Y	70.5	Confident	74.5	Confident	123 Å²	123	75.2 Å²	75.2	48%	0.482	37%	0.373	S	S	.	.	H	α-helix	trans	-95.6	-9.9	-169.4	-69.4	-77	0	0	0	114.3	I145 Y151	I145-Y149 HydrophobicContact CG2-CD2 3.82Å; I145-Y149 HydrophobicContact CG2-CE2 4.23Å; I145-Y149 VanDerWaalsContact O-CD2 3.3Å; I145-Y149 WeakPolarHBondContact O-CD2 3.31Å; I145-Y149 PolarHBondContact O-N 3.1Å; Y149-Y151 VanDerWaalsContact CB-CD2 3.41Å; Y149-Y151 HydrophobicContact CD1-CE2 4.16Å; Y149-Y151 HydrophobicContact CG-CD2 4.33Å; Y149-Y151 AromaticContact CG-CE2 3.85Å; Y149-Y151 HydrophobicContact CG-CE2 3.85Å; Y149-Y151 PolarHBondContact O-N 2.85Å
150	S	64.7	Low	73.4	Confident	81 Å²	81	79.4 Å²	79.4	57%	0.566	39%	0.389	S	S	*	.			trans	44.2	35.7	178.4	-56.3	0	0	0	0	113.8	T146 D152	T146-S150 PolarHBondContact O-N 2.86Å; S150-D152 PolarHBondContact O-N 3.33Å; S150-D152 VanDerWaalsContact O-N 3.15Å
151	Y	63.8	Low	72.3	Confident	152 Å²	152	77.5 Å²	77.5	60%	0.596	38%	0.379	S	S	*	.			trans	-67.8	114.3	173.2	-72.9	-67	0	0	0	107.7	Y149 I153 Q208	Y149-Y151 VanDerWaalsContact CB-CD2 3.41Å; Y149-Y151 HydrophobicContact CD1-CE2 4.16Å; Y149-Y151 HydrophobicContact CG-CD2 4.33Å; Y149-Y151 AromaticContact CG-CE2 3.85Å; Y149-Y151 HydrophobicContact CG-CE2 3.85Å; Y149-Y151 PolarHBondContact O-N 2.85Å; Y151-I153 VanDerWaalsContact C-N 3.33Å; Y151-I153 PolarHBondContact O-N 2.89Å; Y151-I153 VanDerWaalsContact O-N 3.07Å; Y151-Q208 PolarHBondContact O-NE2 3.19Å
152	D	62.5	Low	71.3	Confident	97 Å²	97	80.4 Å²	80.4	52%	0.519	39%	0.389	S	S	.	.			trans	-81.5	82.9	172.8	-165.8	-5.8	0	0	0	109.4	S150 T154	S150-D152 PolarHBondContact O-N 3.33Å; S150-D152 VanDerWaalsContact O-N 3.15Å; D152-T154 WeakPolarHBondContact OD1-CB 2.94Å; D152-T154 PolarHBondContact OD1-N 2.91Å; D152-T154 PolarHBondContact OD1-OG1 3.2Å
153	I	64.4	Low	70.6	Confident	73 Å²	73	83 Å²	83	37%	0.374	41%	0.406	S	S	.	.			trans	-78.8	-8.9	174.4	-52.5	171.2	0	0	0	109.9	Y151 V155 F156 F157 I204	Y151-I153 VanDerWaalsContact C-N 3.33Å; Y151-I153 PolarHBondContact O-N 2.89Å; Y151-I153 VanDerWaalsContact O-N 3.07Å; I153-V155 VanDerWaalsContact C-N 3.32Å; I153-V155 PolarHBondContact O-N 3.48Å; I153-F156 HydrophobicContact CG2-CB 4.29Å; I153-F156 HydrophobicContact CG2-CD1 4.3Å; I153-F156 WeakPolarHBondContact O-CB 3.31Å; I153-F156 PolarHBondContact O-N 3.45Å; I153-F157 PolarHBondContact O-N 3.49Å; I153-I204 HydrophobicContact CD1-CG2 4.38Å
154	T	65.3	Low	70	Confident	20 Å²	20	83.2 Å²	83.2	12%	0.123	41%	0.407	C	S	.	.	H	α-helix	trans	-59.5	-42.8	-173.1	-25.5	0	0	0	0	111.7	D152 F156 F157 Y158 M205	D152-T154 WeakPolarHBondContact OD1-CB 2.94Å; D152-T154 PolarHBondContact OD1-N 2.91Å; D152-T154 PolarHBondContact OD1-OG1 3.2Å; T154-F156 PolarHBondContact O-N 3.12Å; T154-F157 WeakPolarHBondContact O-CB 3.49Å; T154-F157 PolarHBondContact O-N 3.12Å; T154-Y158 HydrophobicContact CG2-CD2 4.18Å; T154-Y158 HydrophobicContact CG2-CE2 3.58Å; T154-Y158 WeakPolarHBondContact O-CD2 3.1Å; T154-Y158 PolarHBondContact O-N 3.49Å; T154-M205 HydrophobicContact CG2-CE 3.69Å
155	V	64.9	Low	69.5	Low	98 Å²	98	79.3 Å²	79.3	59%	0.594	38%	0.383	S	S	*	.	H	α-helix	trans	-60.5	-45.1	176.7	-178.8	0	0	0	0	111.4	I153 F157 Y158 Q159	I153-V155 VanDerWaalsContact C-N 3.32Å; I153-V155 PolarHBondContact O-N 3.48Å; V155-F157 VanDerWaalsContact C-N 3.35Å; V155-Y158 PolarHBondContact O-N 3.25Å; V155-Q159 PolarHBondContact O-N 3.2Å
156	F	63.9	Low	69.1	Low	101 Å²	101	78 Å²	78	44%	0.443	38%	0.379	S	S	.	.	H	α-helix	trans	-61.9	-44.7	176.2	-178.9	-91	0	0	0	110.6	I153 T154 Y158 Q159 Y160 F164	I153-F156 HydrophobicContact CG2-CB 4.29Å; I153-F156 HydrophobicContact CG2-CD1 4.3Å; I153-F156 WeakPolarHBondContact O-CB 3.31Å; I153-F156 PolarHBondContact O-N 3.45Å; T154-F156 PolarHBondContact O-N 3.12Å; F156-Y158 PolarHBondContact O-N 2.99Å; F156-Q159 PolarHBondContact O-N 3.46Å; F156-Y160 AromaticContact CD1-CD2 3.86Å; F156-Y160 HydrophobicContact CD1-CD2 3.86Å; F156-Y160 AromaticContact CD2-CD2 3.52Å; F156-Y160 HydrophobicContact CD2-CD2 3.52Å; F156-Y160 AromaticContact CD2-CE2 3.37Å; F156-Y160 HydrophobicContact CD2-CE2 3.37Å; F156-Y160 AromaticContact CE1-CD2 3.68Å; F156-Y160 HydrophobicContact CE1-CD2 3.68Å; F156-Y160 HydrophobicContact CE1-CE2 4.32Å; F156-Y160 HydrophobicContact CE1-CG 4.29Å; F156-Y160 AromaticContact CE2-CD2 3.34Å; F156-Y160 HydrophobicContact CE2-CD2 3.34Å; F156-Y160 AromaticContact CE2-CE2 3.1Å; F156-Y160 HydrophobicContact CE2-CE2 3.1Å; F156-Y160 HydrophobicContact CE2-CG 4.41Å; F156-Y160 AromaticContact CE2-CZ 4Å; F156-Y160 AromaticContact CG-CD2 3.77Å; F156-Y160 HydrophobicContact CG-CD2 3.77Å; F156-Y160 HydrophobicContact CG-CE2 4.1Å; F156-Y160 AromaticContact CZ-CD2 3.41Å; F156-Y160 HydrophobicContact CZ-CD2 3.41Å; F156-Y160 VanDerWaalsContact CZ-CD2 3.41Å; F156-Y160 AromaticContact CZ-CE2 3.63Å; F156-Y160 HydrophobicContact CZ-CE2 3.63Å; F156-Y160 HydrophobicContact CZ-CG 4.13Å; F156-Y160 WeakPolarHBondContact O-CD2 3.13Å; F156-Y160 PolarHBondContact O-N 3.04Å; F156-F164 HydrophobicContact CD1-CE2 4.48Å; F156-F164 HydrophobicContact CE1-CE2 4.05Å; F156-F164 HydrophobicContact CE1-CZ 4.3Å
157	F	64.4	Low	68.8	Low	9 Å²	9	79.7 Å²	79.7	4%	0.039	39%	0.39	C	S	.	.	H	α-helix	trans	-59.5	-43.3	179.2	-176.3	-94.2	0	0	0	112.7	I153 T154 V155 Q159 Y160 F161 F164 V165 F202 M205	I153-F157 PolarHBondContact O-N 3.49Å; T154-F157 WeakPolarHBondContact O-CB 3.49Å; T154-F157 PolarHBondContact O-N 3.12Å; V155-F157 VanDerWaalsContact C-N 3.35Å; F157-Q159 VanDerWaalsContact C-N 3.35Å; F157-Q159 PolarHBondContact O-N 2.74Å; F157-Y160 CarbonylContact O-C 3.1Å; F157-Y160 VanDerWaalsContact O-C 3.3Å; F157-Y160 PolarHBondContact O-N 3.18Å; F157-F161 HydrophobicContact CE1-CD2 4.28Å; F157-F161 WeakPolarHBondContact O-CA 3.38Å; F157-F161 PolarHBondContact O-N 3.01Å; F157-F164 HydrophobicContact CD2-CB 4.35Å; F157-F164 AromaticContact CD2-CD2 3.89Å; F157-F164 HydrophobicContact CD2-CD2 3.89Å; F157-F164 HydrophobicContact CD2-CE2 4.43Å; F157-F164 HydrophobicContact CD2-CG 4.14Å; F157-F164 HydrophobicContact CE2-CB 3.67Å; F157-F164 HydrophobicContact CE2-CD2 4.08Å; F157-F164 AromaticContact CE2-CG 3.89Å; F157-F164 HydrophobicContact CE2-CG 3.89Å; F157-F164 HydrophobicContact CZ-CB 4.36Å; F157-V165 HydrophobicContact CZ-CG2 4.27Å; F157-F202 HydrophobicContact CZ-CE1 4.17Å; F157-M205 HydrophobicContact CB-CE 3.63Å; F157-M205 HydrophobicContact CB-SD 3.73Å; F157-M205 HydrophobicContact CD1-CE 3.52Å; F157-M205 HydrophobicContact CD1-SD 4.26Å; F157-M205 HydrophobicContact CD2-CE 4.19Å; F157-M205 HydrophobicContact CD2-CG 4.2Å; F157-M205 HydrophobicContact CD2-SD 3.83Å; F157-M205 HydrophobicContact CE1-CE 4.22Å; F157-M205 HydrophobicContact CE2-CG 4.34Å; F157-M205 HydrophobicContact CG-CE 3.5Å; F157-M205 HydrophobicContact CG-CG 4.43Å; F157-M205 HydrophobicContact CG-SD 3.67Å
158	Y	65.7	Low	68.9	Low	51 Å²	51	77.3 Å²	77.3	20%	0.2	38%	0.375	C	S	.	.	H	α-helix	trans	-64.2	-40	177	-77.1	-66.2	0	0	0	112.5	T154 V155 F156 Y160 F161 M273 E276	T154-Y158 HydrophobicContact CG2-CD2 4.18Å; T154-Y158 HydrophobicContact CG2-CE2 3.58Å; T154-Y158 WeakPolarHBondContact O-CD2 3.1Å; T154-Y158 PolarHBondContact O-N 3.49Å; V155-Y158 PolarHBondContact O-N 3.25Å; F156-Y158 PolarHBondContact O-N 2.99Å; Y158-Y160 VanDerWaalsContact C-N 3.32Å; Y158-Y160 PolarHBondContact O-N 3.44Å; Y158-F161 WeakPolarHBondContact O-CB 3.25Å; Y158-F161 PolarHBondContact O-N 3.28Å; Y158-M273 HydrophobicContact CE1-SD 3.73Å; Y158-E276 WeakPolarHBondContact CE1-OE2 3.28Å; Y158-E276 HydrophobicContact CE2-CG 4.07Å; Y158-E276 WeakPolarHBondContact CE2-OE1 3.42Å; Y158-E276 VanDerWaalsContact CZ-OE2 3.23Å; Y158-E276 VanDerWaalsContact OH-CB 3.25Å; Y158-E276 WeakPolarHBondContact OH-CB 3.4Å; Y158-E276 WeakPolarHBondContact OH-CG 3.38Å; Y158-E276 PolarHBondContact OH-OE2 3.25Å
159	Q	66.6	Low	69	Low	143 Å²	143	73.1 Å²	73.1	67%	0.668	36%	0.36	S	S	*	.	H	α-helix	trans	-66.6	-37	177.9	-170.1	172.8	1.6	0	0	111.9	V155 F156 F157	V155-Q159 PolarHBondContact O-N 3.2Å; F156-Q159 PolarHBondContact O-N 3.46Å; F157-Q159 VanDerWaalsContact C-N 3.35Å; F157-Q159 PolarHBondContact O-N 2.74Å
160	Y	67.9	Low	69.5	Low	93 Å²	93	72.1 Å²	72.1	37%	0.365	36%	0.358	S	S	.	.	T	Hydrogen-bonded Turn	trans	-102.7	24.7	179.4	-62	-75.6	0	0	0	112.9	F156 F157 Y158 F162 V163 F164	F156-Y160 AromaticContact CD1-CD2 3.86Å; F156-Y160 HydrophobicContact CD1-CD2 3.86Å; F156-Y160 AromaticContact CD2-CD2 3.52Å; F156-Y160 HydrophobicContact CD2-CD2 3.52Å; F156-Y160 AromaticContact CD2-CE2 3.37Å; F156-Y160 HydrophobicContact CD2-CE2 3.37Å; F156-Y160 AromaticContact CE1-CD2 3.68Å; F156-Y160 HydrophobicContact CE1-CD2 3.68Å; F156-Y160 HydrophobicContact CE1-CE2 4.32Å; F156-Y160 HydrophobicContact CE1-CG 4.29Å; F156-Y160 AromaticContact CE2-CD2 3.34Å; F156-Y160 HydrophobicContact CE2-CD2 3.34Å; F156-Y160 AromaticContact CE2-CE2 3.1Å; F156-Y160 HydrophobicContact CE2-CE2 3.1Å; F156-Y160 HydrophobicContact CE2-CG 4.41Å; F156-Y160 AromaticContact CE2-CZ 4Å; F156-Y160 AromaticContact CG-CD2 3.77Å; F156-Y160 HydrophobicContact CG-CD2 3.77Å; F156-Y160 HydrophobicContact CG-CE2 4.1Å; F156-Y160 AromaticContact CZ-CD2 3.41Å; F156-Y160 HydrophobicContact CZ-CD2 3.41Å; F156-Y160 VanDerWaalsContact CZ-CD2 3.41Å; F156-Y160 AromaticContact CZ-CE2 3.63Å; F156-Y160 HydrophobicContact CZ-CE2 3.63Å; F156-Y160 HydrophobicContact CZ-CG 4.13Å; F156-Y160 WeakPolarHBondContact O-CD2 3.13Å; F156-Y160 PolarHBondContact O-N 3.04Å; F157-Y160 CarbonylContact O-C 3.1Å; F157-Y160 VanDerWaalsContact O-C 3.3Å; F157-Y160 PolarHBondContact O-N 3.18Å; Y158-Y160 VanDerWaalsContact C-N 3.32Å; Y158-Y160 PolarHBondContact O-N 3.44Å; Y160-F162 VanDerWaalsContact C-N 3.29Å; Y160-F162 PolarHBondContact O-N 3.07Å; Y160-V163 HydrophobicContact CD1-CG2 4.22Å; Y160-V163 WeakPolarHBondContact O-CA 3.45Å; Y160-V163 VanDerWaalsContact O-CB 3.28Å; Y160-V163 WeakPolarHBondContact O-CB 3.27Å; Y160-V163 PolarHBondContact O-N 3.29Å; Y160-F164 WeakPolarHBondContact O-CD2 3.31Å; Y160-F164 PolarHBondContact O-N 2.84Å
161	F	67	Low	70.2	Confident	31 Å²	31	68.5 Å²	68.5	14%	0.136	33%	0.332	C	S	.	.	H	α-helix	trans	-50.5	-48.5	-173.6	167.8	-107.8	0	0	0	112.8	F157 Y158 V163 F164 V165 Y269	F157-F161 HydrophobicContact CE1-CD2 4.28Å; F157-F161 WeakPolarHBondContact O-CA 3.38Å; F157-F161 PolarHBondContact O-N 3.01Å; Y158-F161 WeakPolarHBondContact O-CB 3.25Å; Y158-F161 PolarHBondContact O-N 3.28Å; F161-V163 PolarHBondContact O-N 3.23Å; F161-F164 PolarHBondContact O-N 3.31Å; F161-V165 HydrophobicContact CD2-CB 4.38Å; F161-V165 HydrophobicContact CD2-CG2 3.86Å; F161-V165 HydrophobicContact CE2-CB 3.67Å; F161-V165 HydrophobicContact CE2-CG1 4.11Å; F161-V165 HydrophobicContact CE2-CG2 3.25Å; F161-V165 HydrophobicContact CZ-CB 3.86Å; F161-V165 HydrophobicContact CZ-CG1 3.95Å; F161-V165 HydrophobicContact CZ-CG2 3.96Å; F161-V165 PolarHBondContact O-N 2.91Å; F161-Y269 HydrophobicContact CD2-CD2 4.24Å; F161-Y269 AromaticContact CD2-CE2 3.5Å; F161-Y269 HydrophobicContact CD2-CE2 3.5Å; F161-Y269 VanDerWaalsContact CD2-CE2 3.5Å; F161-Y269 AromaticContact CD2-CZ 3.8Å; F161-Y269 HydrophobicContact CE1-CE1 4.47Å; F161-Y269 HydrophobicContact CE2-CD1 4.2Å; F161-Y269 AromaticContact CE2-CD2 3.43Å; F161-Y269 HydrophobicContact CE2-CD2 3.43Å; F161-Y269 VanDerWaalsContact CE2-CD2 3.43Å; F161-Y269 AromaticContact CE2-CE1 3.72Å; F161-Y269 HydrophobicContact CE2-CE1 3.72Å; F161-Y269 AromaticContact CE2-CE2 2.89Å; F161-Y269 HydrophobicContact CE2-CE2 2.89Å; F161-Y269 HydrophobicContact CE2-CG 4.05Å; F161-Y269 AromaticContact CE2-CZ 3.01Å; F161-Y269 VanDerWaalsContact CE2-OH 3.26Å; F161-Y269 WeakPolarHBondContact CE2-OH 3.48Å; F161-Y269 HydrophobicContact CZ-CD1 4.13Å; F161-Y269 HydrophobicContact CZ-CD2 4.19Å; F161-Y269 AromaticContact CZ-CE1 3.48Å; F161-Y269 HydrophobicContact CZ-CE1 3.48Å; F161-Y269 VanDerWaalsContact CZ-CE1 3.48Å; F161-Y269 AromaticContact CZ-CE2 3.6Å; F161-Y269 HydrophobicContact CZ-CE2 3.6Å; F161-Y269 HydrophobicContact CZ-CG 4.42Å; F161-Y269 AromaticContact CZ-CZ 3.14Å; F161-Y269 WeakPolarHBondContact CZ-OH 3.34Å
162	F	69.4	Low	70.7	Confident	154 Å²	154	61.2 Å²	61.2	68%	0.675	30%	0.304	S	S	*	.	H	α-helix	trans	-64.7	-28.9	179.5	-70	-78.2	0	0	0	112.7	Y160 F164 V166	Y160-F162 VanDerWaalsContact C-N 3.29Å; Y160-F162 PolarHBondContact O-N 3.07Å; F162-F164 VanDerWaalsContact C-N 3.33Å; F162-V166 HydrophobicContact CB-CG2 4.15Å; F162-V166 HydrophobicContact CD1-CG2 3.85Å; F162-V166 WeakPolarHBondContact O-CB 3.16Å; F162-V166 WeakPolarHBondContact O-CG2 3.33Å; F162-V166 PolarHBondContact O-N 3.49Å
163	V	72.7	Confident	71.4	Confident	94 Å²	94	60 Å²	60	57%	0.57	30%	0.297	S	S	*	.	H	α-helix	trans	-70.5	-31.5	179.3	-175.7	0	0	0	0	111.3	Y160 F161 P167	Y160-V163 HydrophobicContact CD1-CG2 4.22Å; Y160-V163 WeakPolarHBondContact O-CA 3.45Å; Y160-V163 VanDerWaalsContact O-CB 3.28Å; Y160-V163 WeakPolarHBondContact O-CB 3.27Å; Y160-V163 PolarHBondContact O-N 3.29Å; F161-V163 PolarHBondContact O-N 3.23Å; V163-P167 WeakPolarHBondContact O-CD 3.44Å; V163-P167 WeakPolarHBondContact O-CG 3.24Å
164	F	72.9	Confident	72.2	Confident	46 Å²	46	60.8 Å²	60.8	20%	0.202	30%	0.297	C	S	.	.	H	α-helix	trans	-92.1	-42.9	-179.6	-72.2	-77.7	0	0	0	113.2	F156 F157 Y160 F161 F162 L168	F156-F164 HydrophobicContact CD1-CE2 4.48Å; F156-F164 HydrophobicContact CE1-CE2 4.05Å; F156-F164 HydrophobicContact CE1-CZ 4.3Å; F157-F164 HydrophobicContact CD2-CB 4.35Å; F157-F164 AromaticContact CD2-CD2 3.89Å; F157-F164 HydrophobicContact CD2-CD2 3.89Å; F157-F164 HydrophobicContact CD2-CE2 4.43Å; F157-F164 HydrophobicContact CD2-CG 4.14Å; F157-F164 HydrophobicContact CE2-CB 3.67Å; F157-F164 HydrophobicContact CE2-CD2 4.08Å; F157-F164 AromaticContact CE2-CG 3.89Å; F157-F164 HydrophobicContact CE2-CG 3.89Å; F157-F164 HydrophobicContact CZ-CB 4.36Å; Y160-F164 WeakPolarHBondContact O-CD2 3.31Å; Y160-F164 PolarHBondContact O-N 2.84Å; F161-F164 PolarHBondContact O-N 3.31Å; F162-F164 VanDerWaalsContact C-N 3.33Å; F164-L168 WeakPolarHBondContact O-CB 3.43Å
165	V	74.1	Confident	72.7	Confident	9 Å²	9	60 Å²	60	6%	0.055	29%	0.292	C	S	.	.	H	α-helix	trans	-84.4	-33.9	-172.5	174	0	0	0	0	113.1	F157 F161 L168 L169 Y269	F157-V165 HydrophobicContact CZ-CG2 4.27Å; F161-V165 HydrophobicContact CD2-CB 4.38Å; F161-V165 HydrophobicContact CD2-CG2 3.86Å; F161-V165 HydrophobicContact CE2-CB 3.67Å; F161-V165 HydrophobicContact CE2-CG1 4.11Å; F161-V165 HydrophobicContact CE2-CG2 3.25Å; F161-V165 HydrophobicContact CZ-CB 3.86Å; F161-V165 HydrophobicContact CZ-CG1 3.95Å; F161-V165 HydrophobicContact CZ-CG2 3.96Å; F161-V165 PolarHBondContact O-N 2.91Å; V165-L168 WeakPolarHBondContact O-CB 3.49Å; V165-L168 PolarHBondContact O-N 3.18Å; V165-L169 HydrophobicContact CG1-CD1 4.05Å; V165-L169 HydrophobicContact CG1-CG 4.21Å; V165-L169 PolarHBondContact O-N 2.75Å; V165-Y269 HydrophobicContact CG2-CD2 4.44Å
166	V	77.3	Confident	73.2	Confident	53 Å²	53	56.9 Å²	56.9	32%	0.321	27%	0.272	S	S	.	.	H	α-helix	trans	-64.8	-50.7	-178.2	178	0	0	0	0	111.4	F162 L168 L169 F170	F162-V166 HydrophobicContact CB-CG2 4.15Å; F162-V166 HydrophobicContact CD1-CG2 3.85Å; F162-V166 WeakPolarHBondContact O-CB 3.16Å; F162-V166 WeakPolarHBondContact O-CG2 3.33Å; F162-V166 PolarHBondContact O-N 3.49Å; V166-L168 PolarHBondContact O-N 2.95Å; V166-L169 PolarHBondContact O-N 3.3Å; V166-F170 HydrophobicContact CG1-CD2 3.52Å; V166-F170 HydrophobicContact CG1-CE2 3.43Å; V166-F170 VanDerWaalsContact CG1-CE2 3.43Å; V166-F170 WeakPolarHBondContact O-CD2 3.18Å; V166-F170 PolarHBondContact O-N 3.37Å; V166-F170 VanDerWaalsContact O-N 3.11Å
167	P	75.7	Confident	74	Confident	46 Å²	46	56 Å²	56	30%	0.299	27%	0.271	S	S	.	.	H	α-helix	trans	-58.5	-33.6	175.4	-25.5	37.3	0	0	0	112.5	V163 F170 T171 F194	V163-P167 WeakPolarHBondContact O-CD 3.44Å; V163-P167 WeakPolarHBondContact O-CG 3.24Å; P167-F170 PolarHBondContact O-N 3.31Å; P167-T171 WeakPolarHBondContact O-CB 3.22Å; P167-T171 PolarHBondContact O-N 2.91Å; P167-T171 PolarHBondContact O-OG1 3.2Å; P167-F194 HydrophobicContact CB-CE1 3.89Å; P167-F194 HydrophobicContact CB-CZ 3.86Å
168	L	77.7	Confident	74.5	Confident	2 Å²	2	58.2 Å²	58.2	1%	0.01	28%	0.281	C	S	.	.	H	α-helix	trans	-70.7	-37.7	-179.2	-168.9	58	0	0	0	113	F164 V165 V166 P172 T195 H198 F202 I265	F164-L168 WeakPolarHBondContact O-CB 3.43Å; V165-L168 WeakPolarHBondContact O-CB 3.49Å; V165-L168 PolarHBondContact O-N 3.18Å; V166-L168 PolarHBondContact O-N 2.95Å; L168-P172 WeakPolarHBondContact O-CD 3.34Å; L168-T195 HydrophobicContact CD1-CG2 4.39Å; L168-H198 HydrophobicContact CD1-CB 3.31Å; L168-H198 HydrophobicContact CD2-CB 3.96Å; L168-H198 HydrophobicContact CG-CB 4.19Å; L168-F202 HydrophobicContact CD2-CD2 4.16Å; L168-F202 HydrophobicContact CD2-CE2 3.26Å; L168-F202 HydrophobicContact CD2-CZ 3.73Å; L168-I265 HydrophobicContact CB-CG2 4.47Å; L168-I265 HydrophobicContact CD1-CD1 3.95Å; L168-I265 HydrophobicContact CD1-CG1 4.39Å; L168-I265 HydrophobicContact CD2-CB 4.4Å; L168-I265 HydrophobicContact CD2-CD1 4.27Å; L168-I265 HydrophobicContact CD2-CG1 3.91Å; L168-I265 HydrophobicContact CD2-CG2 3.64Å; L168-I265 HydrophobicContact CG-CD1 3.64Å; L168-I265 HydrophobicContact CG-CG1 3.85Å; L168-I265 HydrophobicContact CG-CG2 3.82Å
169	L	77.7	Confident	74.9	Confident	60 Å²	60	56.2 Å²	56.2	31%	0.314	27%	0.274	S	S	.	.	H	α-helix	trans	-69.3	-36.7	173.4	-72.4	174.3	0	0	0	111.9	V165 V166 I173 V262 I265	V165-L169 HydrophobicContact CG1-CD1 4.05Å; V165-L169 HydrophobicContact CG1-CG 4.21Å; V165-L169 PolarHBondContact O-N 2.75Å; V166-L169 PolarHBondContact O-N 3.3Å; L169-I173 VanDerWaalsContact O-CD1 3.31Å; L169-I173 WeakPolarHBondContact O-CD1 3.37Å; L169-I173 WeakPolarHBondContact O-CG1 3.15Å; L169-V262 HydrophobicContact CD2-CG1 4.29Å; L169-I265 HydrophobicContact CD2-CG2 3.94Å; L169-I265 HydrophobicContact CG-CG2 4.45Å
170	F	80.8	Confident	75.3	Confident	101 Å²	101	55.6 Å²	55.6	44%	0.443	27%	0.269	S	S	.	.	H	α-helix	trans	-76.9	-26.5	179.6	-78.3	-65.8	0	0	0	113.6	V166 P167 I173 F174	V166-F170 HydrophobicContact CG1-CD2 3.52Å; V166-F170 HydrophobicContact CG1-CE2 3.43Å; V166-F170 VanDerWaalsContact CG1-CE2 3.43Å; V166-F170 WeakPolarHBondContact O-CD2 3.18Å; V166-F170 PolarHBondContact O-N 3.37Å; V166-F170 VanDerWaalsContact O-N 3.11Å; P167-F170 PolarHBondContact O-N 3.31Å; F170-I173 HydrophobicContact CD1-CD1 4.37Å; F170-I173 WeakPolarHBondContact O-CB 3.29Å; F170-I173 PolarHBondContact O-N 3Å; F170-I173 VanDerWaalsContact O-N 3.15Å; F170-F174 HydrophobicContact CB-CD2 3.94Å; F170-F174 HydrophobicContact CB-CE2 3.71Å; F170-F174 HydrophobicContact CG-CE2 4.36Å; F170-F174 WeakPolarHBondContact O-CD2 3.3Å; F170-F174 PolarHBondContact O-N 2.95Å
171	T	79.5	Confident	75.8	Confident	5 Å²	5	55.7 Å²	55.7	3%	0.031	28%	0.28	C	S	.	.	H	α-helix	trans	-59.5	-52.2	-176.3	-68.7	0	0	0	0	113.2	P167 I173 F174 I175 F191 F194 T195	P167-T171 WeakPolarHBondContact O-CB 3.22Å; P167-T171 PolarHBondContact O-N 2.91Å; P167-T171 PolarHBondContact O-OG1 3.2Å; T171-I173 VanDerWaalsContact C-N 3.26Å; T171-I173 PolarHBondContact O-N 3.47Å; T171-F174 PolarHBondContact O-N 3.03Å; T171-I175 HydrophobicContact CG2-CD1 4.15Å; T171-I175 WeakPolarHBondContact O-CG1 3.24Å; T171-I175 PolarHBondContact O-N 3.41Å; T171-F191 HydrophobicContact CG2-CB 3.76Å; T171-F191 HydrophobicContact CG2-CD1 3.73Å; T171-F191 HydrophobicContact CG2-CG 4.15Å; T171-F191 VanDerWaalsContact CG2-O 3.24Å; T171-F191 WeakPolarHBondContact CG2-O 3.36Å; T171-F194 HydrophobicContact CG2-CD1 4.04Å; T171-F194 WeakPolarHBondContact OG1-CD1 3.34Å; T171-F194 WeakPolarHBondContact OG1-CE1 3.47Å; T171-T195 WeakPolarHBondContact CG2-OG1 3.27Å
172	P	74.4	Confident	76	Confident	0 Å²	0	56.3 Å²	56.3	0%	0	30%	0.295	C	S	.	.	H	α-helix	trans	-60.6	-34.6	173.7	-22.5	32.2	0	0	0	113.3	L168 I175 L176 T258 L261 V262 I265	L168-P172 WeakPolarHBondContact O-CD 3.34Å; P172-I175 WeakPolarHBondContact O-CB 3.44Å; P172-I175 PolarHBondContact O-N 3.08Å; P172-L176 PolarHBondContact O-N 3.22Å; P172-T258 HydrophobicContact CB-CG2 3.71Å; P172-T258 VanDerWaalsContact O-CG2 3.23Å; P172-T258 WeakPolarHBondContact O-CG2 3.18Å; P172-L261 HydrophobicContact CG-CB 4.38Å; P172-V262 HydrophobicContact CB-CG2 3.55Å; P172-V262 HydrophobicContact CG-CG2 3.79Å; P172-I265 HydrophobicContact CG-CD1 4.09Å
173	I	78.2	Confident	75.8	Confident	72 Å²	72	54.9 Å²	54.9	37%	0.369	29%	0.288	S	S	.	.	H	α-helix	trans	-67	-43.3	178.3	-61.3	171.8	0	0	0	110.1	L169 F170 T171 L176 I177	L169-I173 VanDerWaalsContact O-CD1 3.31Å; L169-I173 WeakPolarHBondContact O-CD1 3.37Å; L169-I173 WeakPolarHBondContact O-CG1 3.15Å; F170-I173 HydrophobicContact CD1-CD1 4.37Å; F170-I173 WeakPolarHBondContact O-CB 3.29Å; F170-I173 PolarHBondContact O-N 3Å; F170-I173 VanDerWaalsContact O-N 3.15Å; T171-I173 VanDerWaalsContact C-N 3.26Å; T171-I173 PolarHBondContact O-N 3.47Å; I173-L176 WeakPolarHBondContact O-CB 3.34Å; I173-L176 PolarHBondContact O-N 3.03Å; I173-I177 HydrophobicContact CG2-CD1 4.07Å; I173-I177 WeakPolarHBondContact O-CG1 3.21Å; I173-I177 PolarHBondContact O-N 3.45Å
174	F	80.4	Confident	75.4	Confident	89 Å²	89	55.8 Å²	55.8	39%	0.39	29%	0.287	S	S	.	.	H	α-helix	trans	-63.7	-43.5	175	-77.9	-57.1	0	0	0	111.5	F170 T171 L176 I177 F178 F191	F170-F174 HydrophobicContact CB-CD2 3.94Å; F170-F174 HydrophobicContact CB-CE2 3.71Å; F170-F174 HydrophobicContact CG-CE2 4.36Å; F170-F174 WeakPolarHBondContact O-CD2 3.3Å; F170-F174 PolarHBondContact O-N 2.95Å; T171-F174 PolarHBondContact O-N 3.03Å; F174-L176 PolarHBondContact O-N 2.89Å; F174-I177 HydrophobicContact CD1-CD1 4.49Å; F174-I177 PolarHBondContact O-N 2.87Å; F174-F178 HydrophobicContact CB-CD2 4.18Å; F174-F178 HydrophobicContact CB-CE2 4.05Å; F174-F178 HydrophobicContact CD1-CE2 4.2Å; F174-F178 HydrophobicContact CG-CE2 4.47Å; F174-F178 WeakPolarHBondContact O-CD2 3.07Å; F174-F178 PolarHBondContact O-N 2.94Å; F174-F191 HydrophobicContact CB-CE1 4.18Å; F174-F191 HydrophobicContact CB-CE2 4.09Å; F174-F191 HydrophobicContact CB-CZ 3.88Å; F174-F191 HydrophobicContact CD2-CE1 4.48Å; F174-F191 HydrophobicContact CG-CZ 4.34Å
175	I	75.3	Confident	74.9	Confident	2 Å²	2	58.7 Å²	58.7	1%	0.01	30%	0.303	C	S	.	.	H	α-helix	trans	-51.1	-49.5	172.8	-70	157.9	0	0	0	109.8	T171 P172 I177 F178 T179 F191 M192	T171-I175 HydrophobicContact CG2-CD1 4.15Å; T171-I175 WeakPolarHBondContact O-CG1 3.24Å; T171-I175 PolarHBondContact O-N 3.41Å; P172-I175 WeakPolarHBondContact O-CB 3.44Å; P172-I175 PolarHBondContact O-N 3.08Å; I175-I177 PolarHBondContact O-N 3.05Å; I175-F178 PolarHBondContact O-N 3.4Å; I175-T179 PolarHBondContact O-N 2.9Å; I175-T179 PolarHBondContact O-OG1 3.37Å; I175-F191 HydrophobicContact CD1-CB 3.57Å; I175-F191 HydrophobicContact CG1-CB 3.31Å; I175-F191 HydrophobicContact CG1-CD2 4.23Å; I175-F191 HydrophobicContact CG1-CG 4.02Å; I175-M192 HydrophobicContact CD1-CG 4Å; I175-M192 HydrophobicContact CD1-SD 3.34Å; I175-M192 WeakPolarHBondContact CD1-SD 3.43Å
176	L	76.1	Confident	74.6	Confident	34 Å²	34	64.4 Å²	64.4	18%	0.178	33%	0.333	C	S	.	.	H	α-helix	trans	-60.1	-48.4	-179.7	-164.7	76	0	0	0	112.8	P172 I173 F174 F178 T179 F180 F255 T258	P172-L176 PolarHBondContact O-N 3.22Å; I173-L176 WeakPolarHBondContact O-CB 3.34Å; I173-L176 PolarHBondContact O-N 3.03Å; F174-L176 PolarHBondContact O-N 2.89Å; L176-F178 VanDerWaalsContact C-N 3.3Å; L176-F178 PolarHBondContact O-N 3.32Å; L176-T179 PolarHBondContact O-N 2.68Å; L176-F180 HydrophobicContact CD1-CD2 4.32Å; L176-F180 HydrophobicContact CD1-CE2 3.79Å; L176-F180 HydrophobicContact CD2-CE2 4.19Å; L176-F180 HydrophobicContact CG-CD2 3.91Å; L176-F180 HydrophobicContact CG-CE2 3.72Å; L176-F180 WeakPolarHBondContact O-CD2 3.11Å; L176-F180 PolarHBondContact O-N 2.87Å; L176-F255 HydrophobicContact CD1-CB 4.07Å; L176-F255 HydrophobicContact CD1-CD2 3.56Å; L176-F255 HydrophobicContact CD1-CG 4.3Å; L176-F255 HydrophobicContact CD2-CD2 3.79Å; L176-F255 HydrophobicContact CD2-CE2 3.94Å; L176-F255 HydrophobicContact CG-CD2 4.29Å; L176-T258 HydrophobicContact CB-CG2 4.25Å
177	I	79.9	Confident	74.3	Confident	82 Å²	82	63.5 Å²	63.5	42%	0.421	33%	0.327	S	S	.	.	H	α-helix	trans	-58.2	-45.3	178.2	-67.5	165.4	0	0	0	110	I173 F174 I175 F180 V181	I173-I177 HydrophobicContact CG2-CD1 4.07Å; I173-I177 WeakPolarHBondContact O-CG1 3.21Å; I173-I177 PolarHBondContact O-N 3.45Å; F174-I177 HydrophobicContact CD1-CD1 4.49Å; F174-I177 PolarHBondContact O-N 2.87Å; I175-I177 PolarHBondContact O-N 3.05Å; I177-F180 PolarHBondContact O-N 3.4Å; I177-V181 HydrophobicContact CG2-CG2 4.25Å; I177-V181 WeakPolarHBondContact O-CB 3.43Å; I177-V181 WeakPolarHBondContact O-CG2 3.17Å; I177-V181 PolarHBondContact O-N 2.74Å
178	F	76.1	Confident	74	Confident	56 Å²	56	61.7 Å²	61.7	25%	0.246	32%	0.316	C	S	.	.	H	α-helix	trans	-69	-36.3	-178.9	-72.6	-60.7	0	0	0	113	F174 I175 L176 F180 V181 G182 F183 T187 F191	F174-F178 HydrophobicContact CB-CD2 4.18Å; F174-F178 HydrophobicContact CB-CE2 4.05Å; F174-F178 HydrophobicContact CD1-CE2 4.2Å; F174-F178 HydrophobicContact CG-CE2 4.47Å; F174-F178 WeakPolarHBondContact O-CD2 3.07Å; F174-F178 PolarHBondContact O-N 2.94Å; I175-F178 PolarHBondContact O-N 3.4Å; L176-F178 VanDerWaalsContact C-N 3.3Å; L176-F178 PolarHBondContact O-N 3.32Å; F178-F180 VanDerWaalsContact C-N 3.33Å; F178-F180 PolarHBondContact O-N 3.37Å; F178-V181 PolarHBondContact O-N 2.97Å; F178-G182 PolarHBondContact O-N 3.35Å; F178-G182 VanDerWaalsContact O-N 3.14Å; F178-F183 HydrophobicContact CB-CB 4.17Å; F178-F183 HydrophobicContact CD1-CB 3.98Å; F178-F183 AromaticContact CD1-CD2 4Å; F178-F183 HydrophobicContact CD1-CD2 4Å; F178-F183 HydrophobicContact CD1-CG 4.25Å; F178-F183 HydrophobicContact CE1-CD2 4.49Å; F178-F183 HydrophobicContact CG-CB 4.47Å; F178-F183 PolarHBondContact O-N 3.28Å; F178-T187 HydrophobicContact CB-CG2 4.04Å; F178-T187 HydrophobicContact CD1-CG2 4.08Å; F178-T187 HydrophobicContact CD2-CG2 3.43Å; F178-T187 VanDerWaalsContact CD2-CG2 3.43Å; F178-T187 HydrophobicContact CE1-CG2 4.42Å; F178-T187 HydrophobicContact CE2-CG2 3.86Å; F178-T187 HydrophobicContact CG-CG2 3.58Å; F178-T187 HydrophobicContact CZ-CG2 4.33Å; F178-F191 HydrophobicContact CD2-CD2 4.29Å; F178-F191 AromaticContact CD2-CE2 3.62Å; F178-F191 HydrophobicContact CD2-CE2 3.62Å; F178-F191 HydrophobicContact CD2-CZ 4.46Å; F178-F191 AromaticContact CE2-CE2 3.51Å; F178-F191 HydrophobicContact CE2-CE2 3.51Å; F178-F191 AromaticContact CE2-CZ 3.96Å; F178-F191 HydrophobicContact CE2-CZ 3.96Å
179	T	72.9	Confident	74.1	Confident	9 Å²	9	64.7 Å²	64.7	6%	0.055	33%	0.328	C	S	.	.	H	α-helix	trans	-60.3	-41	171.6	-57.9	0	0	0	0	111.3	I175 L176	I175-T179 PolarHBondContact O-N 2.9Å; I175-T179 PolarHBondContact O-OG1 3.37Å; L176-T179 PolarHBondContact O-N 2.68Å
180	F	75.5	Confident	74.2	Confident	129 Å²	129	67 Å²	67	57%	0.566	34%	0.341	S	S	*	.	H	α-helix	trans	-76.2	-29.7	178.2	-79.7	-70	0	0	0	114.2	L176 I177 F178 G182	L176-F180 HydrophobicContact CD1-CD2 4.32Å; L176-F180 HydrophobicContact CD1-CE2 3.79Å; L176-F180 HydrophobicContact CD2-CE2 4.19Å; L176-F180 HydrophobicContact CG-CD2 3.91Å; L176-F180 HydrophobicContact CG-CE2 3.72Å; L176-F180 WeakPolarHBondContact O-CD2 3.11Å; L176-F180 PolarHBondContact O-N 2.87Å; I177-F180 PolarHBondContact O-N 3.4Å; F178-F180 VanDerWaalsContact C-N 3.33Å; F178-F180 PolarHBondContact O-N 3.37Å; F180-G182 VanDerWaalsContact C-N 3.3Å
181	V	79.1	Confident	74.3	Confident	96 Å²	96	64.7 Å²	64.7	58%	0.582	33%	0.33	S	S	*	.	H	α-helix	trans	-80.3	-12.6	179.1	174.8	0	0	0	0	112.3	I177 F178 F183	I177-V181 HydrophobicContact CG2-CG2 4.25Å; I177-V181 WeakPolarHBondContact O-CB 3.43Å; I177-V181 WeakPolarHBondContact O-CG2 3.17Å; I177-V181 PolarHBondContact O-N 2.74Å; F178-V181 PolarHBondContact O-N 2.97Å; V181-F183 HydrophobicContact CB-CD2 4.39Å; V181-F183 HydrophobicContact CG1-CD2 3.76Å; V181-F183 HydrophobicContact CG1-CE2 3.87Å
182	G	69.5	Low	74.4	Confident	44 Å²	44	64.5 Å²	64.5	45%	0.454	33%	0.329	S	S	.	.	T	Hydrogen-bonded Turn	trans	90.9	17.1	178.8	0	0	0	0	0	114.1	F178 F180 E184	F178-G182 PolarHBondContact O-N 3.35Å; F178-G182 VanDerWaalsContact O-N 3.14Å; F180-G182 VanDerWaalsContact C-N 3.3Å; G182-E184 PolarHBondContact O-N 3.44Å
183	F	67.1	Low	75	Confident	124 Å²	124	67.2 Å²	67.2	54%	0.544	35%	0.346	S	S	.	.			trans	-87.9	65.5	165.9	-74.3	-77.8	0	0	0	108.9	F178 V181 I185	F178-F183 HydrophobicContact CB-CB 4.17Å; F178-F183 HydrophobicContact CD1-CB 3.98Å; F178-F183 AromaticContact CD1-CD2 4Å; F178-F183 HydrophobicContact CD1-CD2 4Å; F178-F183 HydrophobicContact CD1-CG 4.25Å; F178-F183 HydrophobicContact CE1-CD2 4.49Å; F178-F183 HydrophobicContact CG-CB 4.47Å; F178-F183 PolarHBondContact O-N 3.28Å; V181-F183 HydrophobicContact CB-CD2 4.39Å; V181-F183 HydrophobicContact CG1-CD2 3.76Å; V181-F183 HydrophobicContact CG1-CE2 3.87Å; F183-I185 PolarHBondContact O-N 2.87Å
184	E	63.3	Low	75.3	Confident	113 Å²	113	67.5 Å²	67.5	53%	0.528	34%	0.344	S	S	.	.	T	Hydrogen-bonded Turn	trans	-71.4	-37.7	-152	-66.9	-177.4	157.7	0	0	114.7	G182	G182-E184 PolarHBondContact O-N 3.44Å
185	I	63.3	Low	75.6	Confident	107 Å²	107	63.2 Å²	63.2	55%	0.549	33%	0.326	S	S	.	.	T	Hydrogen-bonded Turn	trans	-115.8	-59.4	-162.8	-58	174.1	0	0	0	113.4	F183 T187 K189	F183-I185 PolarHBondContact O-N 2.87Å; I185-T187 PolarHBondContact O-N 2.95Å; I185-K189 HydrophobicContact CG2-CD 4.06Å; I185-K189 WeakPolarHBondContact O-CB 3.47Å; I185-K189 WeakPolarHBondContact O-CG 3.32Å; I185-K189 PolarHBondContact O-N 3.2Å
186	L	66.9	Low	76.4	Confident	129 Å²	129	64.7 Å²	64.7	68%	0.675	33%	0.332	S	S	*	.	H	α-helix	trans	-64.9	-44.5	-170.9	-174.9	66	0	0	0	111.5	K189 L190	L186-K189 PolarHBondContact O-N 2.95Å; L186-L190 HydrophobicContact CG-CD1 4.22Å; L186-L190 WeakPolarHBondContact O-CG 3.06Å; L186-L190 PolarHBondContact O-N 2.97Å
187	T	70	Confident	76.9	Confident	34 Å²	34	66.7 Å²	66.7	21%	0.209	34%	0.342	C	S	.	.	H	α-helix	trans	-66.3	-47.2	-177.5	-52.3	0	0	0	0	111.2	F178 I185 K189 L190 F191	F178-T187 HydrophobicContact CB-CG2 4.04Å; F178-T187 HydrophobicContact CD1-CG2 4.08Å; F178-T187 HydrophobicContact CD2-CG2 3.43Å; F178-T187 VanDerWaalsContact CD2-CG2 3.43Å; F178-T187 HydrophobicContact CE1-CG2 4.42Å; F178-T187 HydrophobicContact CE2-CG2 3.86Å; F178-T187 HydrophobicContact CG-CG2 3.58Å; F178-T187 HydrophobicContact CZ-CG2 4.33Å; I185-T187 PolarHBondContact O-N 2.95Å; T187-K189 PolarHBondContact O-N 3.37Å; T187-L190 PolarHBondContact O-N 3.13Å; T187-F191 HydrophobicContact CG2-CD2 3.74Å; T187-F191 HydrophobicContact CG2-CE2 3.45Å; T187-F191 VanDerWaalsContact CG2-CE2 3.45Å; T187-F191 WeakPolarHBondContact O-CD2 3.14Å; T187-F191 PolarHBondContact O-N 3.25Å; T187-F191 VanDerWaalsContact O-N 3.12Å
188	S	70.9	Confident	77.2	Confident	8 Å²	8	63.7 Å²	63.7	6%	0.056	33%	0.326	C	S	.	.	H	α-helix	trans	-56.9	-49.4	176	-179.1	0	0	0	0	111.2	L190 F191 M192	S188-L190 PolarHBondContact O-N 3.24Å; S188-F191 PolarHBondContact O-N 2.67Å; S188-M192 VanDerWaalsContact O-CG 3.29Å; S188-M192 WeakPolarHBondContact O-CG 3.42Å; S188-M192 PolarHBondContact O-N 2.95Å
189	K	78.5	Confident	77.8	Confident	64 Å²	64	61 Å²	61	28%	0.278	32%	0.315	S	S	.	.	H	α-helix	trans	-60.2	-42.8	179.5	-71.2	-173.4	-179.8	-155	0	112.8	I185 L186 T187 F191 M192 V193 L244 E246	I185-K189 HydrophobicContact CG2-CD 4.06Å; I185-K189 WeakPolarHBondContact O-CB 3.47Å; I185-K189 WeakPolarHBondContact O-CG 3.32Å; I185-K189 PolarHBondContact O-N 3.2Å; L186-K189 PolarHBondContact O-N 2.95Å; T187-K189 PolarHBondContact O-N 3.37Å; K189-F191 PolarHBondContact O-N 2.73Å; K189-M192 PolarHBondContact O-N 2.95Å; K189-V193 WeakPolarHBondContact O-CG2 3.36Å; K189-V193 PolarHBondContact O-N 3.28Å; K189-L244 HydrophobicContact CB-CD2 4.05Å; K189-L244 HydrophobicContact CG-CD2 4.41Å; K189-L244 PolarHBondContact NZ-O 3.33Å; K189-L244 WeakPolarHBondContact O-CD2 3.44Å; K189-E246 PolarHBondContact NZ-O 2.72Å
190	L	81.1	Confident	78.7	Confident	110 Å²	110	61.5 Å²	61.5	58%	0.576	32%	0.316	S	S	*	.	H	α-helix	trans	-62	-43.4	177.6	-73	172.6	0	0	0	112.5	L186 T187 S188 M192 V193 F194	L186-L190 HydrophobicContact CG-CD1 4.22Å; L186-L190 WeakPolarHBondContact O-CG 3.06Å; L186-L190 PolarHBondContact O-N 2.97Å; T187-L190 PolarHBondContact O-N 3.13Å; S188-L190 PolarHBondContact O-N 3.24Å; L190-M192 VanDerWaalsContact C-N 3.28Å; L190-M192 PolarHBondContact O-N 2.95Å; L190-V193 PolarHBondContact O-N 2.68Å; L190-F194 PolarHBondContact O-N 3.05Å
191	F	81.6	Confident	79.2	Confident	51 Å²	51	59.9 Å²	59.9	22%	0.224	31%	0.309	C	S	.	.	H	α-helix	trans	-67.3	-30.2	176.6	-80.6	-62	0	0	0	112.6	T171 F174 I175 F178 T187 S188 K189 F194 T195	T171-F191 HydrophobicContact CG2-CB 3.76Å; T171-F191 HydrophobicContact CG2-CD1 3.73Å; T171-F191 HydrophobicContact CG2-CG 4.15Å; T171-F191 VanDerWaalsContact CG2-O 3.24Å; T171-F191 WeakPolarHBondContact CG2-O 3.36Å; F174-F191 HydrophobicContact CB-CE1 4.18Å; F174-F191 HydrophobicContact CB-CE2 4.09Å; F174-F191 HydrophobicContact CB-CZ 3.88Å; F174-F191 HydrophobicContact CD2-CE1 4.48Å; F174-F191 HydrophobicContact CG-CZ 4.34Å; I175-F191 HydrophobicContact CD1-CB 3.57Å; I175-F191 HydrophobicContact CG1-CB 3.31Å; I175-F191 HydrophobicContact CG1-CD2 4.23Å; I175-F191 HydrophobicContact CG1-CG 4.02Å; F178-F191 HydrophobicContact CD2-CD2 4.29Å; F178-F191 AromaticContact CD2-CE2 3.62Å; F178-F191 HydrophobicContact CD2-CE2 3.62Å; F178-F191 HydrophobicContact CD2-CZ 4.46Å; F178-F191 AromaticContact CE2-CE2 3.51Å; F178-F191 HydrophobicContact CE2-CE2 3.51Å; F178-F191 AromaticContact CE2-CZ 3.96Å; F178-F191 HydrophobicContact CE2-CZ 3.96Å; T187-F191 HydrophobicContact CG2-CD2 3.74Å; T187-F191 HydrophobicContact CG2-CE2 3.45Å; T187-F191 VanDerWaalsContact CG2-CE2 3.45Å; T187-F191 WeakPolarHBondContact O-CD2 3.14Å; T187-F191 PolarHBondContact O-N 3.25Å; T187-F191 VanDerWaalsContact O-N 3.12Å; S188-F191 PolarHBondContact O-N 2.67Å; K189-F191 PolarHBondContact O-N 2.73Å; F191-F194 WeakPolarHBondContact O-CB 3.22Å; F191-F194 PolarHBondContact O-N 3.01Å; F191-T195 PolarHBondContact O-N 3.27Å; F191-T195 PolarHBondContact O-OG1 2.96Å
192	M	82.7	Confident	79.5	Confident	2 Å²	2	55.6 Å²	55.6	1%	0.01	28%	0.283	C	S	.	.	H	α-helix	trans	-71.7	-35.7	173.8	-66	-58.4	-56.1	0	0	112.5	I175 S188 K189 L190 F194 T195 F196 T243 L261	I175-M192 HydrophobicContact CD1-CG 4Å; I175-M192 HydrophobicContact CD1-SD 3.34Å; I175-M192 WeakPolarHBondContact CD1-SD 3.43Å; S188-M192 VanDerWaalsContact O-CG 3.29Å; S188-M192 WeakPolarHBondContact O-CG 3.42Å; S188-M192 PolarHBondContact O-N 2.95Å; K189-M192 PolarHBondContact O-N 2.95Å; L190-M192 VanDerWaalsContact C-N 3.28Å; L190-M192 PolarHBondContact O-N 2.95Å; M192-F194 VanDerWaalsContact C-N 3.31Å; M192-F194 PolarHBondContact O-N 3.1Å; M192-T195 PolarHBondContact O-N 3.4Å; M192-F196 WeakPolarHBondContact O-CB 3.35Å; M192-F196 PolarHBondContact O-N 3.31Å; M192-T243 HydrophobicContact CB-CG2 4.34Å; M192-T243 HydrophobicContact CE-CG2 4.36Å; M192-T243 HydrophobicContact CG-CG2 3.63Å; M192-T243 HydrophobicContact SD-CG2 4.45Å; M192-L261 HydrophobicContact CE-CD1 3.88Å; M192-L261 HydrophobicContact SD-CD1 4.37Å
193	V	86.1	Confident	80.4	Confident	56 Å²	56	53.8 Å²	53.8	34%	0.339	26%	0.263	S	S	.	.	H	α-helix	trans	-59.6	-44.8	168.5	177.7	0	0	0	0	110.4	K189 L190 T195 F196 I197 L244	K189-V193 WeakPolarHBondContact O-CG2 3.36Å; K189-V193 PolarHBondContact O-N 3.28Å; L190-V193 PolarHBondContact O-N 2.68Å; V193-T195 VanDerWaalsContact C-N 3.34Å; V193-T195 PolarHBondContact O-N 3.31Å; V193-F196 WeakPolarHBondContact O-CB 3.47Å; V193-F196 PolarHBondContact O-N 2.7Å; V193-I197 HydrophobicContact CG1-CD1 3.97Å; V193-I197 WeakPolarHBondContact O-CG1 3.27Å; V193-I197 PolarHBondContact O-N 3.25Å; V193-L244 HydrophobicContact CG2-CD1 3.96Å; V193-L244 HydrophobicContact CG2-CD2 3.68Å; V193-L244 HydrophobicContact CG2-CG 4.45Å
194	F	85.9	Confident	81.3	Confident	78 Å²	78	49.2 Å²	49.2	34%	0.342	24%	0.244	S	C	.	.	H	α-helix	trans	-59.9	-46.2	176.6	-173.1	-97.5	0	0	0	111.3	P167 T171 L190 F191 M192 F196 I197 H198	P167-F194 HydrophobicContact CB-CE1 3.89Å; P167-F194 HydrophobicContact CB-CZ 3.86Å; T171-F194 HydrophobicContact CG2-CD1 4.04Å; T171-F194 WeakPolarHBondContact OG1-CD1 3.34Å; T171-F194 WeakPolarHBondContact OG1-CE1 3.47Å; L190-F194 PolarHBondContact O-N 3.05Å; F191-F194 WeakPolarHBondContact O-CB 3.22Å; F191-F194 PolarHBondContact O-N 3.01Å; M192-F194 VanDerWaalsContact C-N 3.31Å; M192-F194 PolarHBondContact O-N 3.1Å; F194-F196 PolarHBondContact O-N 2.81Å; F194-I197 PolarHBondContact O-N 3.3Å; F194-H198 AromaticContact CD1-CE1 3.49Å; F194-H198 VanDerWaalsContact CD1-CE1 3.49Å; F194-H198 WeakPolarHBondContact CD1-CE1 3.22Å; F194-H198 AromaticContact CD1-ND1 3.58Å; F194-H198 AromaticContact CD2-CE1 3.75Å; F194-H198 AromaticContact CE1-CE1 3.05Å; F194-H198 WeakPolarHBondContact CE1-CE1 3.26Å; F194-H198 AromaticContact CE1-ND1 3.59Å; F194-H198 AromaticContact CE1-NE2 3.49Å; F194-H198 WeakPolarHBondContact CE1-NE2 3.19Å; F194-H198 AromaticContact CE2-CE1 3.34Å; F194-H198 WeakPolarHBondContact CE2-CE1 3.21Å; F194-H198 AromaticContact CG-CE1 3.84Å; F194-H198 AromaticContact CG-ND1 3.92Å; F194-H198 AromaticContact CZ-CE1 2.98Å; F194-H198 WeakPolarHBondContact CZ-CE1 3.45Å; F194-H198 AromaticContact CZ-ND1 3.92Å; F194-H198 AromaticContact CZ-NE2 3.44Å; F194-H198 WeakPolarHBondContact CZ-NE2 3.47Å; F194-H198 PolarHBondContact O-N 2.7Å; F194-H198 PolarHBondContact O-ND1 3.24Å
195	T	86.3	Confident	82.1	Confident	0 Å²	0	44.1 Å²	44.1	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-60	-43.6	176.5	-54.5	0	0	0	0	111.8	L168 T171 F191 M192 V193 I197 H198 F199 S240	L168-T195 HydrophobicContact CD1-CG2 4.39Å; T171-T195 WeakPolarHBondContact CG2-OG1 3.27Å; F191-T195 PolarHBondContact O-N 3.27Å; F191-T195 PolarHBondContact O-OG1 2.96Å; M192-T195 PolarHBondContact O-N 3.4Å; V193-T195 VanDerWaalsContact C-N 3.34Å; V193-T195 PolarHBondContact O-N 3.31Å; T195-I197 PolarHBondContact O-N 3.25Å; T195-H198 PolarHBondContact O-N 2.93Å; T195-F199 HydrophobicContact CG2-CD2 3.91Å; T195-F199 HydrophobicContact CG2-CE2 3.73Å; T195-F199 WeakPolarHBondContact O-CD2 3.16Å; T195-F199 PolarHBondContact O-N 3.27Å; T195-S240 WeakPolarHBondContact CG2-OG 3.43Å
196	F	90.5	Very high	83.1	Confident	33 Å²	33	39.1 Å²	39.1	15%	0.145	19%	0.194	C	C	.	.	H	α-helix	trans	-57.2	-49.6	174.9	167	-98.5	0	0	0	111.8	V135 M192 V193 F194 H198 F199 Q200 S237 L241	V135-F196 HydrophobicContact CG2-CD2 4.34Å; V135-F196 HydrophobicContact CG2-CE2 3.72Å; M192-F196 WeakPolarHBondContact O-CB 3.35Å; M192-F196 PolarHBondContact O-N 3.31Å; V193-F196 WeakPolarHBondContact O-CB 3.47Å; V193-F196 PolarHBondContact O-N 2.7Å; F194-F196 PolarHBondContact O-N 2.81Å; F196-H198 PolarHBondContact O-N 2.9Å; F196-F199 PolarHBondContact O-N 3.08Å; F196-Q200 HydrophobicContact CE1-CG 3.99Å; F196-Q200 HydrophobicContact CE2-CG 4.05Å; F196-Q200 HydrophobicContact CZ-CG 3.73Å; F196-Q200 WeakPolarHBondContact O-CG 3.4Å; F196-Q200 PolarHBondContact O-N 3.48Å; F196-S237 WeakPolarHBondContact CD2-OG 3.49Å; F196-S237 WeakPolarHBondContact CE2-OG 3.34Å; F196-L241 HydrophobicContact CD2-CB 4Å; F196-L241 HydrophobicContact CD2-CD1 4.31Å; F196-L241 HydrophobicContact CE2-CB 4.4Å; F196-L241 HydrophobicContact CE2-CD1 4.46Å; F196-L241 HydrophobicContact CE2-CD2 4.3Å; F196-L241 HydrophobicContact CG-CD1 4.42Å
197	I	88.3	Confident	83.8	Confident	75 Å²	75	33 Å²	33	39%	0.385	16%	0.162	S	C	.	.	H	α-helix	trans	-57.7	-40.4	178	-68.5	167.5	0	0	0	110.6	V193 F194 T195 Q200 F201	V193-I197 HydrophobicContact CG1-CD1 3.97Å; V193-I197 WeakPolarHBondContact O-CG1 3.27Å; V193-I197 PolarHBondContact O-N 3.25Å; F194-I197 PolarHBondContact O-N 3.3Å; T195-I197 PolarHBondContact O-N 3.25Å; I197-Q200 WeakPolarHBondContact O-CB 3.2Å; I197-Q200 PolarHBondContact O-N 3.43Å; I197-F201 HydrophobicContact CG2-CD2 4.05Å; I197-F201 HydrophobicContact CG2-CE2 3.79Å; I197-F201 VanDerWaalsContact O-CD2 3.29Å; I197-F201 WeakPolarHBondContact O-CD2 3.43Å; I197-F201 PolarHBondContact O-N 3.2Å
198	H	86	Confident	84.2	Confident	20 Å²	20	31.8 Å²	31.8	9%	0.093	15%	0.154	C	C	.	.	H	α-helix	trans	-66.8	-40.8	178.7	-76.8	64.6	0	0	0	112.8	L168 F194 T195 F196 Q200 F201 F202	L168-H198 HydrophobicContact CD1-CB 3.31Å; L168-H198 HydrophobicContact CD2-CB 3.96Å; L168-H198 HydrophobicContact CG-CB 4.19Å; F194-H198 AromaticContact CD1-CE1 3.49Å; F194-H198 VanDerWaalsContact CD1-CE1 3.49Å; F194-H198 WeakPolarHBondContact CD1-CE1 3.22Å; F194-H198 AromaticContact CD1-ND1 3.58Å; F194-H198 AromaticContact CD2-CE1 3.75Å; F194-H198 AromaticContact CE1-CE1 3.05Å; F194-H198 WeakPolarHBondContact CE1-CE1 3.26Å; F194-H198 AromaticContact CE1-ND1 3.59Å; F194-H198 AromaticContact CE1-NE2 3.49Å; F194-H198 WeakPolarHBondContact CE1-NE2 3.19Å; F194-H198 AromaticContact CE2-CE1 3.34Å; F194-H198 WeakPolarHBondContact CE2-CE1 3.21Å; F194-H198 AromaticContact CG-CE1 3.84Å; F194-H198 AromaticContact CG-ND1 3.92Å; F194-H198 AromaticContact CZ-CE1 2.98Å; F194-H198 WeakPolarHBondContact CZ-CE1 3.45Å; F194-H198 AromaticContact CZ-ND1 3.92Å; F194-H198 AromaticContact CZ-NE2 3.44Å; F194-H198 WeakPolarHBondContact CZ-NE2 3.47Å; F194-H198 PolarHBondContact O-N 2.7Å; F194-H198 PolarHBondContact O-ND1 3.24Å; T195-H198 PolarHBondContact O-N 2.93Å; F196-H198 PolarHBondContact O-N 2.9Å; H198-Q200 VanDerWaalsContact C-N 3.26Å; H198-Q200 PolarHBondContact O-N 3.4Å; H198-F201 WeakPolarHBondContact O-CA 3.12Å; H198-F201 WeakPolarHBondContact O-CB 3.49Å; H198-F201 PolarHBondContact O-N 3.33Å; H198-F201 VanDerWaalsContact O-N 3.1Å; H198-F202 PolarHBondContact O-N 3.09Å
199	F	89	Confident	84.3	Confident	0 Å²	0	32.5 Å²	32.5	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-63.9	-33.5	172.9	-82.1	-72.4	0	0	0	112.1	T195 F196 F201 F202 T203 V233 C236 L261 I265	T195-F199 HydrophobicContact CG2-CD2 3.91Å; T195-F199 HydrophobicContact CG2-CE2 3.73Å; T195-F199 WeakPolarHBondContact O-CD2 3.16Å; T195-F199 PolarHBondContact O-N 3.27Å; F196-F199 PolarHBondContact O-N 3.08Å; F199-F201 VanDerWaalsContact C-N 3.3Å; F199-F201 PolarHBondContact O-N 2.79Å; F199-F202 HydrophobicContact CD1-CD2 4.01Å; F199-F202 HydrophobicContact CE1-CD2 4.25Å; F199-F202 CarbonylContact O-C 3.59Å; F199-F202 WeakPolarHBondContact O-CA 3.44Å; F199-F202 WeakPolarHBondContact O-CB 3.49Å; F199-F202 PolarHBondContact O-N 3.13Å; F199-F202 VanDerWaalsContact O-N 3.08Å; F199-T203 PolarHBondContact O-N 2.98Å; F199-T203 PolarHBondContact O-OG1 3.1Å; F199-V233 HydrophobicContact CB-CG1 4.38Å; F199-V233 HydrophobicContact CD1-CB 4.47Å; F199-V233 HydrophobicContact CD1-CG1 4.28Å; F199-V233 HydrophobicContact CD1-CG2 4.47Å; F199-V233 WeakPolarHBondContact O-CG1 3.21Å; F199-C236 HydrophobicContact CD1-CB 3.87Å; F199-C236 HydrophobicContact CD2-CB 4.05Å; F199-C236 HydrophobicContact CE1-CB 3.37Å; F199-C236 HydrophobicContact CE2-CB 3.59Å; F199-C236 HydrophobicContact CG-CB 4.19Å; F199-C236 HydrophobicContact CZ-CB 3.22Å; F199-L261 HydrophobicContact CE2-CD2 3.92Å; F199-L261 HydrophobicContact CZ-CD2 4.31Å; F199-I265 HydrophobicContact CE2-CG1 4.22Å; F199-I265 HydrophobicContact CZ-CG1 3.73Å
200	Q	90.3	Very high	84	Confident	18 Å²	18	29.8 Å²	29.8	8%	0.084	15%	0.147	C	C	.	.	H	α-helix	trans	-63.8	-35.1	172	-65.6	-60.5	-53	0	0	112.2	S139 L142 F196 I197 H198 T203 I204 S237	S139-Q200 PolarHBondContact OG-NE2 3.07Å; L142-Q200 HydrophobicContact CD1-CB 3.95Å; L142-Q200 VanDerWaalsContact CD1-OE1 3.23Å; F196-Q200 HydrophobicContact CE1-CG 3.99Å; F196-Q200 HydrophobicContact CE2-CG 4.05Å; F196-Q200 HydrophobicContact CZ-CG 3.73Å; F196-Q200 WeakPolarHBondContact O-CG 3.4Å; F196-Q200 PolarHBondContact O-N 3.48Å; I197-Q200 WeakPolarHBondContact O-CB 3.2Å; I197-Q200 PolarHBondContact O-N 3.43Å; H198-Q200 VanDerWaalsContact C-N 3.26Å; H198-Q200 PolarHBondContact O-N 3.4Å; Q200-T203 VanDerWaalsContact O-CB 3.3Å; Q200-T203 WeakPolarHBondContact O-CB 3.34Å; Q200-T203 PolarHBondContact O-N 2.99Å; Q200-I204 PolarHBondContact O-N 3Å; Q200-S237 PolarHBondContact NE2-OG 3.5Å
201	F	86.5	Confident	83.3	Confident	96 Å²	96	25.8 Å²	25.8	42%	0.421	13%	0.125	S	C	.	.	H	α-helix	trans	-64.1	-42.1	168.3	-81.1	-74.5	0	0	0	112.2	I197 H198 F199 T203 I204 M205	I197-F201 HydrophobicContact CG2-CD2 4.05Å; I197-F201 HydrophobicContact CG2-CE2 3.79Å; I197-F201 VanDerWaalsContact O-CD2 3.29Å; I197-F201 WeakPolarHBondContact O-CD2 3.43Å; I197-F201 PolarHBondContact O-N 3.2Å; H198-F201 WeakPolarHBondContact O-CA 3.12Å; H198-F201 WeakPolarHBondContact O-CB 3.49Å; H198-F201 PolarHBondContact O-N 3.33Å; H198-F201 VanDerWaalsContact O-N 3.1Å; F199-F201 VanDerWaalsContact C-N 3.3Å; F199-F201 PolarHBondContact O-N 2.79Å; F201-T203 PolarHBondContact O-N 3.17Å; F201-I204 HydrophobicContact CD1-CD1 4.4Å; F201-I204 WeakPolarHBondContact O-CB 2.98Å; F201-I204 PolarHBondContact O-N 3.06Å; F201-I204 VanDerWaalsContact O-N 3.09Å; F201-M205 WeakPolarHBondContact O-CG 3.49Å; F201-M205 PolarHBondContact O-N 3.44Å
202	F	86.4	Confident	82.1	Confident	6 Å²	6	24.2 Å²	24.2	3%	0.026	12%	0.123	C	C	.	.	H	α-helix	trans	-62.4	-28.3	173.6	-77.7	-43	0	0	0	113.2	F157 L168 H198 F199 M205 T206 V233 I265 V268 I272	F157-F202 HydrophobicContact CZ-CE1 4.17Å; L168-F202 HydrophobicContact CD2-CD2 4.16Å; L168-F202 HydrophobicContact CD2-CE2 3.26Å; L168-F202 HydrophobicContact CD2-CZ 3.73Å; H198-F202 PolarHBondContact O-N 3.09Å; F199-F202 HydrophobicContact CD1-CD2 4.01Å; F199-F202 HydrophobicContact CE1-CD2 4.25Å; F199-F202 CarbonylContact O-C 3.59Å; F199-F202 WeakPolarHBondContact O-CA 3.44Å; F199-F202 WeakPolarHBondContact O-CB 3.49Å; F199-F202 PolarHBondContact O-N 3.13Å; F199-F202 VanDerWaalsContact O-N 3.08Å; F202-M205 PolarHBondContact O-N 3.01Å; F202-T206 VanDerWaalsContact O-CB 3.29Å; F202-T206 WeakPolarHBondContact O-CB 3.46Å; F202-T206 PolarHBondContact O-N 2.97Å; F202-T206 PolarHBondContact O-OG1 3.4Å; F202-V233 HydrophobicContact CB-CG1 4.11Å; F202-V233 HydrophobicContact CB-CG2 3.78Å; F202-I265 HydrophobicContact CE2-CG2 4.44Å; F202-V268 HydrophobicContact CB-CG1 4.22Å; F202-V268 HydrophobicContact CD1-CG1 3.99Å; F202-V268 HydrophobicContact CD2-CG1 4.11Å; F202-V268 HydrophobicContact CE1-CG1 4.34Å; F202-V268 HydrophobicContact CE2-CG1 4.39Å; F202-V268 HydrophobicContact CG-CG1 3.9Å; F202-I272 HydrophobicContact CD1-CD1 4Å; F202-I272 HydrophobicContact CE1-CD1 4.24Å
203	T	88.3	Confident	80.4	Confident	5 Å²	5	25.7 Å²	25.7	3%	0.031	14%	0.139	C	C	.	.	H	α-helix	trans	-60.1	-50	170.8	-57.6	0	0	0	0	110	L142 F199 Q200 F201 M205 T206 V207 V233	L142-T203 HydrophobicContact CB-CG2 4.4Å; F199-T203 PolarHBondContact O-N 2.98Å; F199-T203 PolarHBondContact O-OG1 3.1Å; Q200-T203 VanDerWaalsContact O-CB 3.3Å; Q200-T203 WeakPolarHBondContact O-CB 3.34Å; Q200-T203 PolarHBondContact O-N 2.99Å; F201-T203 PolarHBondContact O-N 3.17Å; T203-M205 VanDerWaalsContact C-N 3.32Å; T203-M205 PolarHBondContact O-N 3.28Å; T203-T206 PolarHBondContact O-N 2.94Å; T203-V207 VanDerWaalsContact O-CG2 3.27Å; T203-V207 WeakPolarHBondContact O-CG2 3.41Å; T203-V207 PolarHBondContact O-N 3.45Å; T203-V233 WeakPolarHBondContact OG1-CG1 3.13Å
204	I	85.8	Confident	78.3	Confident	29 Å²	29	30.5 Å²	30.5	15%	0.149	16%	0.158	C	C	.	.	H	α-helix	trans	-58.5	-46.6	178.4	-60.7	167.9	0	0	0	110.4	L142 T146 I153 Q200 F201 T206 V207 Q208	L142-I204 HydrophobicContact CB-CG1 4.31Å; L142-I204 HydrophobicContact CD1-CD1 4.41Å; L142-I204 HydrophobicContact CD1-CG1 4.18Å; L142-I204 HydrophobicContact CD2-CD1 4.11Å; L142-I204 HydrophobicContact CD2-CG1 4.24Å; L142-I204 HydrophobicContact CG-CG1 4.49Å; T146-I204 HydrophobicContact CG2-CG2 4.13Å; I153-I204 HydrophobicContact CD1-CG2 4.38Å; Q200-I204 PolarHBondContact O-N 3Å; F201-I204 HydrophobicContact CD1-CD1 4.4Å; F201-I204 WeakPolarHBondContact O-CB 2.98Å; F201-I204 PolarHBondContact O-N 3.06Å; F201-I204 VanDerWaalsContact O-N 3.09Å; I204-T206 PolarHBondContact O-N 3.27Å; I204-V207 PolarHBondContact O-N 3.44Å; I204-Q208 WeakPolarHBondContact O-CG 3.05Å; I204-Q208 PolarHBondContact O-N 3.34Å
205	M	80.4	Confident	75.9	Confident	6 Å²	6	33.9 Å²	33.9	3%	0.03	18%	0.179	C	C	.	.	H	α-helix	trans	-62.8	-42.4	178.7	-66.6	-57.6	-55.2	0	0	112.7	T154 F157 F201 F202 T203 V207 Q208 T209 I272	T154-M205 HydrophobicContact CG2-CE 3.69Å; F157-M205 HydrophobicContact CB-CE 3.63Å; F157-M205 HydrophobicContact CB-SD 3.73Å; F157-M205 HydrophobicContact CD1-CE 3.52Å; F157-M205 HydrophobicContact CD1-SD 4.26Å; F157-M205 HydrophobicContact CD2-CE 4.19Å; F157-M205 HydrophobicContact CD2-CG 4.2Å; F157-M205 HydrophobicContact CD2-SD 3.83Å; F157-M205 HydrophobicContact CE1-CE 4.22Å; F157-M205 HydrophobicContact CE2-CG 4.34Å; F157-M205 HydrophobicContact CG-CE 3.5Å; F157-M205 HydrophobicContact CG-CG 4.43Å; F157-M205 HydrophobicContact CG-SD 3.67Å; F201-M205 WeakPolarHBondContact O-CG 3.49Å; F201-M205 PolarHBondContact O-N 3.44Å; F202-M205 PolarHBondContact O-N 3.01Å; T203-M205 VanDerWaalsContact C-N 3.32Å; T203-M205 PolarHBondContact O-N 3.28Å; M205-V207 VanDerWaalsContact C-N 3.25Å; M205-V207 PolarHBondContact O-N 2.83Å; M205-Q208 PolarHBondContact O-N 3.39Å; M205-T209 WeakPolarHBondContact O-CB 3.36Å; M205-T209 VanDerWaalsContact O-CG2 3.31Å; M205-T209 WeakPolarHBondContact O-CG2 3.49Å; M205-T209 PolarHBondContact O-N 3.03Å; M205-T209 PolarHBondContact O-OG1 2.97Å; M205-I272 HydrophobicContact CB-CD1 4.23Å
206	T	83.2	Confident	73.7	Confident	1 Å²	1	35.2 Å²	35.2	1%	0.006	19%	0.187	C	C	.	.	H	α-helix	trans	-60.9	-41	176.5	-57.7	0	0	0	0	109.7	F202 T203 I204 T209 L210 Q229 M230	F202-T206 VanDerWaalsContact O-CB 3.29Å; F202-T206 WeakPolarHBondContact O-CB 3.46Å; F202-T206 PolarHBondContact O-N 2.97Å; F202-T206 PolarHBondContact O-OG1 3.4Å; T203-T206 PolarHBondContact O-N 2.94Å; I204-T206 PolarHBondContact O-N 3.27Å; T206-T209 WeakPolarHBondContact CA-OG1 3.34Å; T206-T209 PolarHBondContact O-OG1 3.28Å; T206-L210 HydrophobicContact CG2-CD1 4.1Å; T206-L210 WeakPolarHBondContact O-CB 2.93Å; T206-L210 WeakPolarHBondContact O-CD1 3.34Å; T206-L210 WeakPolarHBondContact O-CG 3.15Å; T206-L210 PolarHBondContact O-N 2.96Å; T206-Q229 HydrophobicContact CG2-CB 3.77Å; T206-M230 HydrophobicContact CG2-CB 4.3Å
207	V	81.5	Confident	71.4	Confident	0 Å²	0	41.5 Å²	41.5	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-69.2	-39.9	177.7	178.6	0	0	0	0	112.5	F143 T146 T203 I204 M205 L210 Q211 M230	F143-V207 HydrophobicContact CB-CG2 4.23Å; F143-V207 HydrophobicContact CD2-CB 4.28Å; F143-V207 HydrophobicContact CD2-CG1 4.1Å; F143-V207 HydrophobicContact CD2-CG2 3.16Å; F143-V207 HydrophobicContact CE2-CB 4.49Å; F143-V207 HydrophobicContact CE2-CG1 4.14Å; F143-V207 HydrophobicContact CE2-CG2 3.65Å; F143-V207 HydrophobicContact CG-CG1 4.49Å; F143-V207 HydrophobicContact CG-CG2 3.97Å; T146-V207 HydrophobicContact CG2-CB 4.03Å; T146-V207 HydrophobicContact CG2-CG1 3.73Å; T203-V207 VanDerWaalsContact O-CG2 3.27Å; T203-V207 WeakPolarHBondContact O-CG2 3.41Å; T203-V207 PolarHBondContact O-N 3.45Å; I204-V207 PolarHBondContact O-N 3.44Å; M205-V207 VanDerWaalsContact C-N 3.25Å; M205-V207 PolarHBondContact O-N 2.83Å; V207-L210 WeakPolarHBondContact O-CB 3.44Å; V207-L210 PolarHBondContact O-N 3.32Å; V207-Q211 VanDerWaalsContact O-CG 3.28Å; V207-Q211 WeakPolarHBondContact O-CG 3.44Å; V207-Q211 PolarHBondContact O-N 2.9Å; V207-M230 HydrophobicContact CG2-CE 4.49Å
208	Q	79.1	Confident	69.6	Low	9 Å²	9	39.5 Å²	39.5	4%	0.042	21%	0.208	C	C	.	.	H	α-helix	trans	-66.7	-40.6	176.3	-74.1	170.7	-12.7	0	0	112.3	T146 Y151 I204 M205 L210 Q211 G212	T146-Q208 HydrophobicContact CG2-CG 3.64Å; Y151-Q208 PolarHBondContact O-NE2 3.19Å; I204-Q208 WeakPolarHBondContact O-CG 3.05Å; I204-Q208 PolarHBondContact O-N 3.34Å; M205-Q208 PolarHBondContact O-N 3.39Å; Q208-L210 VanDerWaalsContact C-N 3.31Å; Q208-L210 PolarHBondContact O-N 3.06Å; Q208-Q211 WeakPolarHBondContact O-CB 3.46Å; Q208-Q211 PolarHBondContact O-N 2.84Å; Q208-Q211 VanDerWaalsContact O-N 3.1Å; Q208-G212 PolarHBondContact O-N 3.31Å
209	T	72.4	Confident	68	Low	24 Å²	24	41.5 Å²	41.5	15%	0.147	22%	0.218	C	C	.	.	H	α-helix	trans	-67.9	-33.2	175.6	53.1	0	0	0	0	112	M205 T206 Q211 I272	M205-T209 WeakPolarHBondContact O-CB 3.36Å; M205-T209 VanDerWaalsContact O-CG2 3.31Å; M205-T209 WeakPolarHBondContact O-CG2 3.49Å; M205-T209 PolarHBondContact O-N 3.03Å; M205-T209 PolarHBondContact O-OG1 2.97Å; T206-T209 WeakPolarHBondContact CA-OG1 3.34Å; T206-T209 PolarHBondContact O-OG1 3.28Å; T209-Q211 VanDerWaalsContact C-N 3.31Å; T209-I272 HydrophobicContact CG2-CG2 4.1Å
210	L	73.1	Confident	66.3	Low	6 Å²	6	44.3 Å²	44.3	3%	0.031	24%	0.235	C	C	.	.	H	α-helix	trans	-67.8	-29.1	169.3	-75.6	169.4	0	0	0	113	F35 Y36 V39 T206 V207 Q208 M230	F35-L210 HydrophobicContact CE1-CB 4.41Å; F35-L210 HydrophobicContact CE1-CD2 3.66Å; F35-L210 HydrophobicContact CZ-CD2 3.75Å; Y36-L210 HydrophobicContact CE1-CB 4.34Å; V39-L210 HydrophobicContact CG1-CD1 4.23Å; V39-L210 HydrophobicContact CG1-CD2 4.31Å; V39-L210 HydrophobicContact CG2-CD2 4.04Å; T206-L210 HydrophobicContact CG2-CD1 4.1Å; T206-L210 WeakPolarHBondContact O-CB 2.93Å; T206-L210 WeakPolarHBondContact O-CD1 3.34Å; T206-L210 WeakPolarHBondContact O-CG 3.15Å; T206-L210 PolarHBondContact O-N 2.96Å; V207-L210 WeakPolarHBondContact O-CB 3.44Å; V207-L210 PolarHBondContact O-N 3.32Å; Q208-L210 VanDerWaalsContact C-N 3.31Å; Q208-L210 PolarHBondContact O-N 3.06Å; L210-M230 HydrophobicContact CD1-CE 4.48Å
211	Q	66.3	Low	64.7	Low	27 Å²	27	47.7 Å²	47.7	13%	0.126	25%	0.25	C	S	.	.	H	α-helix	trans	-70.2	-34.1	-179.6	-80.3	165.1	12.7	0	0	113.6	Y36 T146 T147 V207 Q208 T209	Y36-Q211 HydrophobicContact CE1-CG 4.28Å; Y36-Q211 WeakPolarHBondContact OH-CA 3.45Å; Y36-Q211 WeakPolarHBondContact OH-CG 3.33Å; T146-Q211 PolarHBondContact O-NE2 3.4Å; T147-Q211 PolarHBondContact OG1-NE2 3.28Å; V207-Q211 VanDerWaalsContact O-CG 3.28Å; V207-Q211 WeakPolarHBondContact O-CG 3.44Å; V207-Q211 PolarHBondContact O-N 2.9Å; Q208-Q211 WeakPolarHBondContact O-CB 3.46Å; Q208-Q211 PolarHBondContact O-N 2.84Å; Q208-Q211 VanDerWaalsContact O-N 3.1Å; T209-Q211 VanDerWaalsContact C-N 3.31Å
212	G	55.6	Low	64.1	Low	18 Å²	18	44 Å²	44	19%	0.186	24%	0.235	C	C	.	.			trans	65.4	146.5	-168.9	0	0	0	0	0	111.4	Q208	Q208-G212 PolarHBondContact O-N 3.31Å
213	G	47.7	Very low	63.8	Low	33 Å²	33	45.2 Å²	45.2	34%	0.34	24%	0.24	S	C	.	.			trans	-61.8	156.5	167.9	0	0	0	0	0	110.6	D215 V216	G213-D215 PolarHBondContact O-N 3.47Å; G213-V216 VanDerWaalsContact O-CB 3.28Å; G213-V216 WeakPolarHBondContact O-CB 3.13Å; G213-V216 WeakPolarHBondContact O-CG2 3.41Å; G213-V216 PolarHBondContact O-N 3Å
214	H	41.3	Very low	63.7	Low	157 Å²	157	45 Å²	45	73%	0.727	24%	0.239	S	C	*	.	T	Hydrogen-bonded Turn	trans	-50.5	-20.1	-173.8	-125.1	82.4	0	0	0	115.7
215	D	34.8	Very low	63.6	Low	149 Å²	149	43.7 Å²	43.7	80%	0.797	23%	0.232	S	C	*	.	T	Hydrogen-bonded Turn	trans	-103.8	16.7	-177.5	-57.3	-40.2	0	0	0	113.6	G213	G213-D215 PolarHBondContact O-N 3.47Å
216	V	41.4	Very low	63.8	Low	28 Å²	28	43.5 Å²	43.5	17%	0.17	23%	0.231	C	C	.	.			trans	-132.8	106.8	-158.7	-163.1	0	0	0	0	113.2	G213 V218 L279 L283	G213-V216 VanDerWaalsContact O-CB 3.28Å; G213-V216 WeakPolarHBondContact O-CB 3.13Å; G213-V216 WeakPolarHBondContact O-CG2 3.41Å; G213-V216 PolarHBondContact O-N 3Å; V216-V218 PolarHBondContact O-N 3.23Å; V216-V218 VanDerWaalsContact O-N 3.07Å; V216-L279 HydrophobicContact CB-CD1 4.47Å; V216-L279 HydrophobicContact CG1-CD1 3.23Å; V216-L279 HydrophobicContact CG1-CD2 4.19Å; V216-L279 HydrophobicContact CG1-CG 3.63Å; V216-L283 HydrophobicContact CG2-CD2 4.34Å
217	E	42.4	Very low	64.2	Low	165 Å²	165	43.4 Å²	43.4	77%	0.771	23%	0.231	S	C	*	.			trans	-70.3	98.1	167.2	-68.2	175.8	-179.1	0	0	109	E219	E217-E219 PolarHBondContact O-N 3.36Å; E217-E219 VanDerWaalsContact O-N 3.15Å
218	V	49.4	Very low	64.6	Low	33 Å²	33	43.4 Å²	43.4	20%	0.2	23%	0.231	C	C	.	.			trans	-60.1	116.6	158.9	-178.7	0	0	0	0	105.8	F35 V216 V220	F35-V218 HydrophobicContact CD1-CG1 4.4Å; F35-V218 HydrophobicContact CD2-CG1 4.44Å; F35-V218 HydrophobicContact CE1-CB 4.34Å; F35-V218 HydrophobicContact CE1-CG1 3.74Å; F35-V218 HydrophobicContact CE2-CG1 3.78Å; F35-V218 HydrophobicContact CZ-CB 4.42Å; F35-V218 HydrophobicContact CZ-CG1 3.4Å; V216-V218 PolarHBondContact O-N 3.23Å; V216-V218 VanDerWaalsContact O-N 3.07Å; V218-V220 PolarHBondContact O-N 2.91Å
219	E	51.9	Low	65.1	Low	62 Å²	62	43 Å²	43	29%	0.29	23%	0.229	S	C	.	.			trans	-61.8	135.3	-178.8	-85.4	167.3	-147.9	0	0	108.5	R96 E217 E221 D222 K282	R96-E219 IonicContact CZ-OE2 2.84Å; R96-E219 IonicContact NH1-OE2 3.05Å; R96-E219 PolarHBondContact NH1-OE2 2.99Å; R96-E219 IonicContact NH2-OE2 3.84Å; R96-E219 PolarHBondContact NH2-OE2 3.35Å; E217-E219 PolarHBondContact O-N 3.36Å; E217-E219 VanDerWaalsContact O-N 3.15Å; E219-E221 PolarHBondContact O-N 3.23Å; E219-D222 PolarHBondContact O-N 3.26Å; E219-K282 IonicContact OE1-NZ 3.07Å; E219-K282 PolarHBondContact OE1-NZ 3.33Å; E219-K282 IonicContact OE2-NZ 3.84Å; E219-K282 PolarHBondContact OE2-NZ 2.88Å; E219-K282 VanDerWaalsContact OE2-NZ 3.07Å
220	V	54.1	Low	66	Low	58 Å²	58	42.4 Å²	42.4	35%	0.352	22%	0.224	S	C	.	.	T	Hydrogen-bonded Turn	trans	-55.5	-10	179.7	176.8	0	0	0	0	112.6	K38 V218 Y223	K38-V220 HydrophobicContact CD-CG1 3.83Å; V218-V220 PolarHBondContact O-N 2.91Å; V220-Y223 WeakPolarHBondContact O-CD1 3.29Å
221	E	57.9	Low	67	Low	89 Å²	89	42.2 Å²	42.2	42%	0.416	22%	0.223	S	C	.	.	T	Hydrogen-bonded Turn	trans	-86.5	-26.2	-179.5	-58.9	175.7	-178.1	0	0	114.2	R96 E219 Y223	R96-E221 WeakPolarHBondContact CD-OE2 3.49Å; R96-E221 HydrophobicContact CG-CB 4.11Å; R96-E221 WeakPolarHBondContact CG-OE2 3.34Å; R96-E221 IonicContact CZ-OE2 3.04Å; R96-E221 IonicContact NH1-OE2 2.7Å; E219-E221 PolarHBondContact O-N 3.23Å; E221-Y223 VanDerWaalsContact O-CD1 3.32Å; E221-Y223 WeakPolarHBondContact O-CD1 3.47Å; E221-Y223 PolarHBondContact O-N 3.06Å; E221-Y223 VanDerWaalsContact O-N 3.13Å
222	D	72.1	Confident	68.3	Low	18 Å²	18	40.9 Å²	40.9	10%	0.096	22%	0.217	C	C	.	.	T	Hydrogen-bonded Turn	trans	-81.6	9.6	-175.9	-58.9	-15.3	0	0	0	111.9	R96 E219 V224 L225 G226	R96-D222 IonicContact CZ-OD1 3.97Å; R96-D222 IonicContact NE-OD1 3.72Å; R96-D222 IonicContact NH2-OD1 3.84Å; R96-D222 PolarHBondContact NH2-OD1 3.43Å; R96-D222 IonicContact NH2-OD2 2.68Å; E219-D222 PolarHBondContact O-N 3.26Å; D222-V224 PolarHBondContact O-N 3.06Å; D222-L225 PolarHBondContact O-N 2.77Å; D222-G226 PolarHBondContact O-N 3.1Å
223	Y	81.4	Confident	70.1	Confident	33 Å²	33	40.1 Å²	40.1	13%	0.129	21%	0.209	C	C	.	.	H	α-helix	trans	-61.8	-29.3	-178.7	70.3	-81	0	0	0	112.9	K38 V42 V220 E221 S227	K38-Y223 HydrophobicContact CB-CG 4.44Å; V42-Y223 HydrophobicContact CG2-CD2 3.68Å; V42-Y223 HydrophobicContact CG2-CE2 3.66Å; V220-Y223 WeakPolarHBondContact O-CD1 3.29Å; E221-Y223 VanDerWaalsContact O-CD1 3.32Å; E221-Y223 WeakPolarHBondContact O-CD1 3.47Å; E221-Y223 PolarHBondContact O-N 3.06Å; E221-Y223 VanDerWaalsContact O-N 3.13Å; Y223-S227 WeakPolarHBondContact O-CB 3.41Å; Y223-S227 PolarHBondContact O-N 3.49Å; Y223-S227 PolarHBondContact O-OG 3.35Å
224	V	85.7	Confident	72.3	Confident	1 Å²	1	38.8 Å²	38.8	1%	0.006	19%	0.194	C	C	.	.	H	α-helix	trans	-63.2	-48.7	177.1	169.9	0	0	0	0	109.8	L88 N101 L105 D222 S227 M228	L88-V224 HydrophobicContact CD2-CG1 4.12Å; N101-V224 HydrophobicContact CB-CG1 4.44Å; N101-V224 HydrophobicContact CB-CG2 4.06Å; L105-V224 HydrophobicContact CB-CG1 4.28Å; L105-V224 HydrophobicContact CD1-CG1 4.25Å; L105-V224 HydrophobicContact CD2-CG1 4.19Å; L105-V224 HydrophobicContact CG-CG1 4.48Å; D222-V224 PolarHBondContact O-N 3.06Å; V224-S227 PolarHBondContact O-N 3.37Å; V224-S227 PolarHBondContact O-OG 3.07Å; V224-M228 WeakPolarHBondContact O-CB 3.43Å; V224-M228 PolarHBondContact O-N 3.29Å
225	L	83.9	Confident	74.8	Confident	1 Å²	1	31.3 Å²	31.3	1%	0.005	16%	0.159	C	C	.	.	H	α-helix	trans	-64.9	-43.2	-179.8	-175.1	52.8	0	0	0	111.6	L89 E95 D222 S227 M228 Q229 S271 I274 N275	L89-L225 HydrophobicContact CD2-CD1 3.52Å; L89-L225 HydrophobicContact CG-CD1 4.41Å; E95-L225 VanDerWaalsContact OE1-CB 3.29Å; E95-L225 WeakPolarHBondContact OE1-CB 3.3Å; D222-L225 PolarHBondContact O-N 2.77Å; L225-S227 PolarHBondContact O-N 2.91Å; L225-M228 HydrophobicContact CD1-CE 3.73Å; L225-M228 PolarHBondContact O-N 3.4Å; L225-Q229 WeakPolarHBondContact O-CG 3.41Å; L225-Q229 PolarHBondContact O-N 2.87Å; L225-S271 WeakPolarHBondContact CD1-OG 3.27Å; L225-I274 HydrophobicContact CD2-CG2 4.48Å; L225-N275 WeakPolarHBondContact CD2-OD1 3.49Å
226	G	85.2	Confident	77.6	Confident	1 Å²	1	24.2 Å²	24.2	1%	0.01	12%	0.121	C	C	.	.	H	α-helix	trans	-57.5	-46.3	172.7	0	0	0	0	0	113.9	D222 Q229 M230	D222-G226 PolarHBondContact O-N 3.1Å; G226-Q229 PolarHBondContact O-N 3.39Å; G226-M230 PolarHBondContact O-N 3.19Å; G226-M230 VanDerWaalsContact O-N 3.08Å
227	S	89.8	Confident	80.1	Confident	0 Å²	0	22.9 Å²	22.9	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-65.8	-40.3	177.2	68.3	0	0	0	0	112.3	V42 Q46 Y223 V224 L225 M230 F231	V42-S227 VanDerWaalsContact CG1-OG 3.24Å; V42-S227 WeakPolarHBondContact CG1-OG 3.43Å; Q46-S227 PolarHBondContact OE1-O 3.04Å; Y223-S227 WeakPolarHBondContact O-CB 3.41Å; Y223-S227 PolarHBondContact O-N 3.49Å; Y223-S227 PolarHBondContact O-OG 3.35Å; V224-S227 PolarHBondContact O-N 3.37Å; V224-S227 PolarHBondContact O-OG 3.07Å; L225-S227 PolarHBondContact O-N 2.91Å; S227-M230 PolarHBondContact O-N 3.34Å; S227-F231 VanDerWaalsContact O-CB 3.3Å; S227-F231 WeakPolarHBondContact O-CB 3.48Å; S227-F231 PolarHBondContact O-N 3.15Å
228	M	91.4	Very high	82.5	Confident	0 Å²	0	15.2 Å²	15.2	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-60.7	-47.9	175.7	-171.1	-169.9	76.3	0	0	111.5	L88 L89 L105 F108 V224 L225 F231 I232 L267	L88-M228 HydrophobicContact CB-SD 4.16Å; L88-M228 HydrophobicContact CD1-SD 3.67Å; L89-M228 HydrophobicContact CD1-CE 4.2Å; L89-M228 HydrophobicContact CD2-CE 4.03Å; L89-M228 HydrophobicContact CG-CE 4.02Å; L105-M228 HydrophobicContact CD1-CB 3.78Å; L105-M228 HydrophobicContact CD1-CG 4.12Å; F108-M228 HydrophobicContact CD1-CG 3.95Å; F108-M228 HydrophobicContact CE1-CG 3.65Å; F108-M228 HydrophobicContact CE1-SD 4.47Å; F108-M228 HydrophobicContact CZ-CG 4.11Å; V224-M228 WeakPolarHBondContact O-CB 3.43Å; V224-M228 PolarHBondContact O-N 3.29Å; L225-M228 HydrophobicContact CD1-CE 3.73Å; L225-M228 PolarHBondContact O-N 3.4Å; M228-F231 PolarHBondContact O-N 2.92Å; M228-I232 HydrophobicContact CE-CD1 4.23Å; M228-I232 HydrophobicContact CG-CD1 3.94Å; M228-I232 WeakPolarHBondContact O-CD1 3.2Å; M228-I232 VanDerWaalsContact O-CG1 3.27Å; M228-I232 WeakPolarHBondContact O-CG1 3.23Å; M228-I232 PolarHBondContact O-N 3.47Å; M228-L267 HydrophobicContact CE-CD2 4.13Å
229	Q	89.5	Confident	84.5	Confident	0 Å²	0	13.7 Å²	13.7	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-57.9	-51	177	-73.8	172.2	-11.7	0	0	111.4	T206 L225 G226 F231 I232 V233 S271 N275	T206-Q229 HydrophobicContact CG2-CB 3.77Å; L225-Q229 WeakPolarHBondContact O-CG 3.41Å; L225-Q229 PolarHBondContact O-N 2.87Å; G226-Q229 PolarHBondContact O-N 3.39Å; Q229-F231 VanDerWaalsContact C-N 3.29Å; Q229-F231 PolarHBondContact O-N 3.35Å; Q229-I232 PolarHBondContact O-N 2.68Å; Q229-V233 WeakPolarHBondContact O-CG2 3.35Å; Q229-V233 PolarHBondContact O-N 3.02Å; Q229-S271 WeakPolarHBondContact CG-OG 3.44Å; Q229-S271 VanDerWaalsContact NE2-CB 3.34Å; Q229-S271 PolarHBondContact NE2-O 3.43Å; Q229-S271 PolarHBondContact NE2-OG 3.31Å; Q229-N275 PolarHBondContact NE2-ND2 2.91Å; Q229-N275 PolarHBondContact OE1-ND2 3.36Å
230	M	90.6	Very high	86.3	Confident	12 Å²	12	10.8 Å²	10.8	6%	0.059	6%	0.055	C	C	.	.	H	α-helix	trans	-59.4	-42.3	179.3	179.9	175.8	-84.7	0	0	111.4	F43 F143 T206 V207 L210 G226 S227 V233 I234	F43-M230 HydrophobicContact CB-SD 4.26Å; F43-M230 HydrophobicContact CD1-SD 3.99Å; F43-M230 HydrophobicContact CD2-CB 4.34Å; F43-M230 HydrophobicContact CD2-CG 3.81Å; F43-M230 HydrophobicContact CD2-SD 3.95Å; F43-M230 HydrophobicContact CE1-SD 4.39Å; F43-M230 HydrophobicContact CE2-CG 3.97Å; F43-M230 HydrophobicContact CE2-SD 4.36Å; F43-M230 HydrophobicContact CG-CG 4.25Å; F43-M230 HydrophobicContact CG-SD 3.76Å; F143-M230 HydrophobicContact CD2-CE 3.39Å; F143-M230 HydrophobicContact CE2-CE 3.46Å; F143-M230 VanDerWaalsContact CE2-CE 3.46Å; T206-M230 HydrophobicContact CG2-CB 4.3Å; V207-M230 HydrophobicContact CG2-CE 4.49Å; L210-M230 HydrophobicContact CD1-CE 4.48Å; G226-M230 PolarHBondContact O-N 3.19Å; G226-M230 VanDerWaalsContact O-N 3.08Å; S227-M230 PolarHBondContact O-N 3.34Å; M230-V233 PolarHBondContact O-N 3.41Å; M230-I234 HydrophobicContact CG-CD1 3.74Å; M230-I234 WeakPolarHBondContact O-CB 3.3Å; M230-I234 WeakPolarHBondContact O-CG1 3.36Å; M230-I234 PolarHBondContact O-N 3.37Å
231	F	94.5	Very high	88.1	Confident	1 Å²	1	8.8 Å²	8.8	0%	0.004	4%	0.042	C	C	.	.	H	α-helix	trans	-62.2	-46.6	177.9	-174	-108	0	0	0	112.5	F43 Q46 L50 F108 T109 H112 S227 M228 Q229 I234 L235	F43-F231 HydrophobicContact CD2-CB 4.4Å; F43-F231 HydrophobicContact CE2-CD2 4.35Å; Q46-F231 HydrophobicContact CB-CD2 3.56Å; Q46-F231 HydrophobicContact CB-CE2 3.7Å; Q46-F231 HydrophobicContact CB-CG 4.13Å; Q46-F231 HydrophobicContact CB-CZ 4.37Å; L50-F231 HydrophobicContact CB-CE2 4.31Å; L50-F231 HydrophobicContact CB-CZ 4.36Å; L50-F231 HydrophobicContact CD2-CE2 4.45Å; F108-F231 HydrophobicContact CE1-CD1 4.2Å; T109-F231 HydrophobicContact CG2-CE1 3.96Å; T109-F231 HydrophobicContact CG2-CE2 4.23Å; T109-F231 HydrophobicContact CG2-CZ 3.63Å; H112-F231 HydrophobicContact CB-CE1 4.28Å; H112-F231 AromaticContact CD2-CE1 3.93Å; S227-F231 VanDerWaalsContact O-CB 3.3Å; S227-F231 WeakPolarHBondContact O-CB 3.48Å; S227-F231 PolarHBondContact O-N 3.15Å; M228-F231 PolarHBondContact O-N 2.92Å; Q229-F231 VanDerWaalsContact C-N 3.29Å; Q229-F231 PolarHBondContact O-N 3.35Å; F231-I234 PolarHBondContact O-N 3.03Å; F231-L235 HydrophobicContact CD1-CD1 4.08Å; F231-L235 HydrophobicContact CD2-CD1 4.41Å; F231-L235 HydrophobicContact CE1-CD1 3.37Å; F231-L235 HydrophobicContact CE1-CG 4.49Å; F231-L235 HydrophobicContact CE2-CD1 3.75Å; F231-L235 HydrophobicContact CE2-CG 4.31Å; F231-L235 HydrophobicContact CZ-CD1 3.17Å; F231-L235 HydrophobicContact CZ-CG 4.18Å; F231-L235 WeakPolarHBondContact O-CB 3.42Å; F231-L235 PolarHBondContact O-N 2.76Å
232	I	93.9	Very high	89.6	Confident	0 Å²	0	4.6 Å²	4.6	0%	0	2%	0.023	C	C	.	.	H	α-helix	trans	-61.5	-47.2	178	-65.8	156.8	0	0	0	110.8	F108 M228 Q229 I234 L235 C236 N264 L267 V268	F108-I232 HydrophobicContact CE1-CD1 4.22Å; F108-I232 HydrophobicContact CE1-CG1 3.92Å; F108-I232 HydrophobicContact CZ-CD1 3.72Å; F108-I232 HydrophobicContact CZ-CG1 3.6Å; M228-I232 HydrophobicContact CE-CD1 4.23Å; M228-I232 HydrophobicContact CG-CD1 3.94Å; M228-I232 WeakPolarHBondContact O-CD1 3.2Å; M228-I232 VanDerWaalsContact O-CG1 3.27Å; M228-I232 WeakPolarHBondContact O-CG1 3.23Å; M228-I232 PolarHBondContact O-N 3.47Å; Q229-I232 PolarHBondContact O-N 2.68Å; I232-I234 VanDerWaalsContact C-N 3.35Å; I232-I234 PolarHBondContact O-N 3.15Å; I232-L235 PolarHBondContact O-N 2.96Å; I232-C236 VanDerWaalsContact O-CB 3.28Å; I232-C236 WeakPolarHBondContact O-CB 3.49Å; I232-C236 PolarHBondContact O-N 3.18Å; I232-C236 PolarHBondContact O-SG 2.89Å; I232-N264 HydrophobicContact CG2-CB 3.84Å; I232-L267 HydrophobicContact CD1-CD2 3.3Å; I232-V268 HydrophobicContact CB-CG2 4.02Å; I232-V268 HydrophobicContact CG2-CG2 3.47Å; I232-V268 VanDerWaalsContact CG2-CG2 3.47Å
233	V	93.2	Very high	90.1	Very high	1 Å²	1	4 Å²	4	1%	0.006	2%	0.019	C	C	.	.	H	α-helix	trans	-61.3	-45.7	-177.8	170.2	0	0	0	0	110.8	F199 F202 T203 Q229 M230 S237 V268	F199-V233 HydrophobicContact CB-CG1 4.38Å; F199-V233 HydrophobicContact CD1-CB 4.47Å; F199-V233 HydrophobicContact CD1-CG1 4.28Å; F199-V233 HydrophobicContact CD1-CG2 4.47Å; F199-V233 WeakPolarHBondContact O-CG1 3.21Å; F202-V233 HydrophobicContact CB-CG1 4.11Å; F202-V233 HydrophobicContact CB-CG2 3.78Å; T203-V233 WeakPolarHBondContact OG1-CG1 3.13Å; Q229-V233 WeakPolarHBondContact O-CG2 3.35Å; Q229-V233 PolarHBondContact O-N 3.02Å; M230-V233 PolarHBondContact O-N 3.41Å; V233-S237 WeakPolarHBondContact O-CB 3.26Å; V233-S237 PolarHBondContact O-N 3.45Å; V233-V268 HydrophobicContact CG2-CG1 3.91Å; V233-V268 HydrophobicContact CG2-CG2 3.94Å
234	I	94.1	Very high	90.2	Very high	6 Å²	6	4.9 Å²	4.9	3%	0.031	3%	0.026	C	C	.	.	H	α-helix	trans	-65.7	-45.8	179.3	-73.2	171.2	0	0	0	110.9	F43 F132 V135 L136 M230 F231 I232 S237 S238	F43-I234 HydrophobicContact CE1-CD1 4.17Å; F43-I234 HydrophobicContact CE2-CD1 3.51Å; F43-I234 HydrophobicContact CZ-CD1 3.26Å; F132-I234 HydrophobicContact CE2-CG2 3.85Å; F132-I234 HydrophobicContact CZ-CG2 4.44Å; V135-I234 HydrophobicContact CG1-CG2 4.12Å; V135-I234 WeakPolarHBondContact CG1-O 3.43Å; L136-I234 HydrophobicContact CD2-CD1 4.25Å; L136-I234 HydrophobicContact CD2-CG2 3.84Å; M230-I234 HydrophobicContact CG-CD1 3.74Å; M230-I234 WeakPolarHBondContact O-CB 3.3Å; M230-I234 WeakPolarHBondContact O-CG1 3.36Å; M230-I234 PolarHBondContact O-N 3.37Å; F231-I234 PolarHBondContact O-N 3.03Å; I232-I234 VanDerWaalsContact C-N 3.35Å; I232-I234 PolarHBondContact O-N 3.15Å; I234-S237 PolarHBondContact O-N 2.93Å; I234-S238 WeakPolarHBondContact O-CB 3.39Å; I234-S238 PolarHBondContact O-N 2.77Å
235	L	94.3	Very high	90.1	Very high	0 Å²	0	8 Å²	8	0%	0	4%	0.04	C	C	.	.	H	α-helix	trans	-68.6	-40.5	-179.7	-89.6	-177.9	0	0	0	113.4	L50 V116 F132 F231 I232 S237 S238 L239	L50-L235 HydrophobicContact CD1-CD1 4.14Å; L50-L235 HydrophobicContact CD1-CD2 3.89Å; L50-L235 HydrophobicContact CD2-CD1 4.33Å; L50-L235 HydrophobicContact CD2-CD2 3.53Å; L50-L235 HydrophobicContact CD2-CG 4.15Å; L50-L235 HydrophobicContact CG-CD2 4.35Å; V116-L235 HydrophobicContact CG1-CD2 4.24Å; V116-L235 HydrophobicContact CG2-CB 4.42Å; V116-L235 HydrophobicContact CG2-CD1 4.5Å; F132-L235 HydrophobicContact CD2-CD2 4.43Å; F132-L235 HydrophobicContact CE2-CD2 4.1Å; F231-L235 HydrophobicContact CD1-CD1 4.08Å; F231-L235 HydrophobicContact CD2-CD1 4.41Å; F231-L235 HydrophobicContact CE1-CD1 3.37Å; F231-L235 HydrophobicContact CE1-CG 4.49Å; F231-L235 HydrophobicContact CE2-CD1 3.75Å; F231-L235 HydrophobicContact CE2-CG 4.31Å; F231-L235 HydrophobicContact CZ-CD1 3.17Å; F231-L235 HydrophobicContact CZ-CG 4.18Å; F231-L235 WeakPolarHBondContact O-CB 3.42Å; F231-L235 PolarHBondContact O-N 2.76Å; I232-L235 PolarHBondContact O-N 2.96Å; L235-S237 VanDerWaalsContact C-N 3.33Å; L235-S238 PolarHBondContact O-N 2.85Å; L235-L239 WeakPolarHBondContact O-CB 3.42Å; L235-L239 PolarHBondContact O-N 3.26Å
236	C	93.1	Very high	89.8	Confident	0 Å²	0	9 Å²	9	0%	0	4%	0.044	C	C	.	.	H	α-helix	trans	-69.7	-33.7	176.5	-65.8	0	0	0	0	111.9	F199 I232 S240 L261 N264	F199-C236 HydrophobicContact CD1-CB 3.87Å; F199-C236 HydrophobicContact CD2-CB 4.05Å; F199-C236 HydrophobicContact CE1-CB 3.37Å; F199-C236 HydrophobicContact CE2-CB 3.59Å; F199-C236 HydrophobicContact CG-CB 4.19Å; F199-C236 HydrophobicContact CZ-CB 3.22Å; I232-C236 VanDerWaalsContact O-CB 3.28Å; I232-C236 WeakPolarHBondContact O-CB 3.49Å; I232-C236 PolarHBondContact O-N 3.18Å; I232-C236 PolarHBondContact O-SG 2.89Å; C236-S240 WeakPolarHBondContact O-CB 3.32Å; C236-S240 PolarHBondContact O-N 3.36Å; C236-S240 PolarHBondContact O-OG 3.41Å; C236-L261 HydrophobicContact CB-CD2 3.99Å; C236-N264 VanDerWaalsContact SG-CB 3.56Å
237	S	93.5	Very high	89.1	Confident	0 Å²	0	18.9 Å²	18.9	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-64.7	-44	172	-168.1	0	0	0	0	111	F196 Q200 V233 I234 L235 S240 L241	F196-S237 WeakPolarHBondContact CD2-OG 3.49Å; F196-S237 WeakPolarHBondContact CE2-OG 3.34Å; Q200-S237 PolarHBondContact NE2-OG 3.5Å; V233-S237 WeakPolarHBondContact O-CB 3.26Å; V233-S237 PolarHBondContact O-N 3.45Å; I234-S237 PolarHBondContact O-N 2.93Å; L235-S237 VanDerWaalsContact C-N 3.33Å; S237-S240 WeakPolarHBondContact O-CB 3.25Å; S237-S240 PolarHBondContact O-N 2.67Å; S237-L241 PolarHBondContact O-N 3.48Å
238	S	93	Very high	88.2	Confident	4 Å²	4	25.2 Å²	25.2	3%	0.028	12%	0.115	C	C	.	.	H	α-helix	trans	-64.9	-43.5	175.2	170.7	0	0	0	0	112.5	S131 I234 L235 S240 L241 S242	S131-S238 PolarHBondContact OG-OG 3.26Å; I234-S238 WeakPolarHBondContact O-CB 3.39Å; I234-S238 PolarHBondContact O-N 2.77Å; L235-S238 PolarHBondContact O-N 2.85Å; S238-S240 PolarHBondContact O-N 3.35Å; S238-L241 PolarHBondContact O-N 3.09Å; S238-S242 WeakPolarHBondContact O-CB 3.31Å; S238-S242 PolarHBondContact O-N 3.19Å; S238-S242 PolarHBondContact O-OG 3.43Å
239	L	91.9	Very high	87.2	Confident	1 Å²	1	28.2 Å²	28.2	1%	0.005	14%	0.136	C	C	.	.	H	α-helix	trans	-57	-41.3	171.8	176.7	59.8	0	0	0	111.1	V116 I119 T120 L235 S242 T243 K257 F260 L261	V116-L239 HydrophobicContact CG1-CB 4.44Å; I119-L239 HydrophobicContact CB-CD1 4.24Å; I119-L239 HydrophobicContact CD1-CD2 4.49Å; I119-L239 HydrophobicContact CG2-CD1 3.65Å; T120-L239 HydrophobicContact CG2-CD1 3.47Å; T120-L239 VanDerWaalsContact CG2-CD1 3.47Å; L235-L239 WeakPolarHBondContact O-CB 3.42Å; L235-L239 PolarHBondContact O-N 3.26Å; L239-S242 PolarHBondContact O-N 2.86Å; L239-T243 PolarHBondContact O-N 3.5Å; L239-T243 PolarHBondContact O-OG1 3.02Å; L239-K257 HydrophobicContact CD1-CD 4.16Å; L239-K257 HydrophobicContact CD1-CG 4.28Å; L239-K257 HydrophobicContact CD2-CG 4.22Å; L239-K257 HydrophobicContact CG-CD 4.45Å; L239-K257 HydrophobicContact CG-CG 4.27Å; L239-F260 HydrophobicContact CD2-CD1 3.66Å; L239-F260 HydrophobicContact CD2-CE1 3.98Å; L239-L261 HydrophobicContact CD2-CD2 4.07Å; L239-L261 HydrophobicContact CD2-CG 4.26Å
240	S	90.1	Very high	86.6	Confident	0 Å²	0	31.4 Å²	31.4	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-66.4	-42.8	179.8	-58	0	0	0	0	112.7	T195 C236 S237 S238	T195-S240 WeakPolarHBondContact CG2-OG 3.43Å; C236-S240 WeakPolarHBondContact O-CB 3.32Å; C236-S240 PolarHBondContact O-N 3.36Å; C236-S240 PolarHBondContact O-OG 3.41Å; S237-S240 WeakPolarHBondContact O-CB 3.25Å; S237-S240 PolarHBondContact O-N 2.67Å; S238-S240 PolarHBondContact O-N 3.35Å
241	L	91.5	Very high	85.9	Confident	17 Å²	17	35.8 Å²	35.8	9%	0.089	17%	0.171	C	C	.	.	H	α-helix	trans	-70.4	-36	177.8	-168.6	67.9	0	0	0	112.1	I134 V135 F196 S237 S238 T243 L244 F245	I134-L241 HydrophobicContact CB-CD2 3.79Å; I134-L241 HydrophobicContact CD1-CD2 4.25Å; I134-L241 HydrophobicContact CG2-CD2 3.63Å; V135-L241 HydrophobicContact CG2-CB 4.27Å; V135-L241 HydrophobicContact CG2-CD2 3.87Å; F196-L241 HydrophobicContact CD2-CB 4Å; F196-L241 HydrophobicContact CD2-CD1 4.31Å; F196-L241 HydrophobicContact CE2-CB 4.4Å; F196-L241 HydrophobicContact CE2-CD1 4.46Å; F196-L241 HydrophobicContact CE2-CD2 4.3Å; F196-L241 HydrophobicContact CG-CD1 4.42Å; S237-L241 PolarHBondContact O-N 3.48Å; S238-L241 PolarHBondContact O-N 3.09Å; L241-T243 PolarHBondContact O-N 3.42Å; L241-L244 HydrophobicContact CD1-CD1 3.71Å; L241-L244 VanDerWaalsContact O-CB 3.31Å; L241-L244 WeakPolarHBondContact O-CB 3.44Å; L241-L244 WeakPolarHBondContact O-CG 3.29Å; L241-L244 PolarHBondContact O-N 3.39Å; L241-F245 HydrophobicContact CG-CE2 4.48Å
242	S	89.1	Confident	85.3	Confident	1 Å²	1	41 Å²	41	1%	0.007	20%	0.196	C	C	.	.	H	α-helix	trans	-60.9	-32.5	179	-54.4	0	0	0	0	112.3	S131 S238 L239 L244 F245 E246	S131-S242 WeakPolarHBondContact CB-OG 3.47Å; S131-S242 PolarHBondContact OG-OG 3.21Å; S238-S242 WeakPolarHBondContact O-CB 3.31Å; S238-S242 PolarHBondContact O-N 3.19Å; S238-S242 PolarHBondContact O-OG 3.43Å; L239-S242 PolarHBondContact O-N 2.86Å; S242-L244 PolarHBondContact O-N 2.84Å; S242-L244 VanDerWaalsContact O-N 3.13Å; S242-F245 PolarHBondContact O-N 3.32Å; S242-E246 PolarHBondContact O-N 2.94Å
243	T	82.7	Confident	84.8	Confident	4 Å²	4	42.4 Å²	42.4	3%	0.025	20%	0.201	C	C	.	.	H	α-helix	trans	-63.5	-18.7	176.8	-55.8	0	0	0	0	112.9	M192 L239 L241 F245 E246 K257	M192-T243 HydrophobicContact CB-CG2 4.34Å; M192-T243 HydrophobicContact CE-CG2 4.36Å; M192-T243 HydrophobicContact CG-CG2 3.63Å; M192-T243 HydrophobicContact SD-CG2 4.45Å; L239-T243 PolarHBondContact O-N 3.5Å; L239-T243 PolarHBondContact O-OG1 3.02Å; L241-T243 PolarHBondContact O-N 3.42Å; T243-F245 VanDerWaalsContact C-N 3.3Å; T243-E246 WeakPolarHBondContact O-CB 3.05Å; T243-K257 VanDerWaalsContact CG2-NZ 3.29Å; T243-K257 WeakPolarHBondContact OG1-CD 3.42Å; T243-K257 PolarHBondContact OG1-NZ 3.06Å
244	L	83.5	Confident	84.2	Confident	52 Å²	52	42.6 Å²	42.6	27%	0.272	20%	0.202	S	C	.	.	H	α-helix	trans	-69.5	-32.9	172.9	-59.4	-176.6	0	0	0	112.1	K189 V193 L241 S242	K189-L244 HydrophobicContact CB-CD2 4.05Å; K189-L244 HydrophobicContact CG-CD2 4.41Å; K189-L244 PolarHBondContact NZ-O 3.33Å; K189-L244 WeakPolarHBondContact O-CD2 3.44Å; V193-L244 HydrophobicContact CG2-CD1 3.96Å; V193-L244 HydrophobicContact CG2-CD2 3.68Å; V193-L244 HydrophobicContact CG2-CG 4.45Å; L241-L244 HydrophobicContact CD1-CD1 3.71Å; L241-L244 VanDerWaalsContact O-CB 3.31Å; L241-L244 WeakPolarHBondContact O-CB 3.44Å; L241-L244 WeakPolarHBondContact O-CG 3.29Å; L241-L244 PolarHBondContact O-N 3.39Å; S242-L244 PolarHBondContact O-N 2.84Å; S242-L244 VanDerWaalsContact O-N 3.13Å
245	F	83	Confident	83.7	Confident	68 Å²	68	45.9 Å²	45.9	30%	0.298	22%	0.216	S	C	.	.	H	α-helix	trans	-84.1	-17.5	179.9	-54.9	-61.5	0	0	0	112.9	D127 I130 L241 S242 T243 R247	D127-F245 HydrophobicContact CB-CB 3.79Å; D127-F245 HydrophobicContact CB-CD2 4.32Å; D127-F245 HydrophobicContact CB-CG 4.14Å; I130-F245 HydrophobicContact CG2-CZ 4.33Å; L241-F245 HydrophobicContact CG-CE2 4.48Å; S242-F245 PolarHBondContact O-N 3.32Å; T243-F245 VanDerWaalsContact C-N 3.3Å; F245-R247 PolarHBondContact O-N 3.49Å
246	E	78	Confident	83.4	Confident	20 Å²	20	45.9 Å²	45.9	9%	0.093	22%	0.216	C	C	.	.			trans	-53.5	126.1	176	-166.1	170.1	178.3	0	0	111.1	N123 K189 S242 T243 S249 K257	N123-E246 WeakPolarHBondContact OD1-CA 3.44Å; N123-E246 VanDerWaalsContact OD1-CB 3.3Å; N123-E246 WeakPolarHBondContact OD1-CB 3.28Å; N123-E246 WeakPolarHBondContact OD1-CG 3.18Å; K189-E246 PolarHBondContact NZ-O 2.72Å; S242-E246 PolarHBondContact O-N 2.94Å; T243-E246 WeakPolarHBondContact O-CB 3.05Å; E246-S249 WeakPolarHBondContact OE1-CA 3.45Å; E246-K257 IonicContact OE2-NZ 2.69Å; E246-K257 PolarHBondContact OE2-NZ 3.28Å
247	R	71.1	Confident	83.1	Confident	210 Å²	210	46 Å²	46	79%	0.792	22%	0.217	S	C	*	.	S	Bend	trans	-99.6	-44.8	-178.5	-62.9	-175.3	-171.7	-177.6	3.4	111.9	F245	F245-R247 PolarHBondContact O-N 3.49Å
248	D	71.4	Confident	82.7	Confident	133 Å²	133	46.5 Å²	46.5	71%	0.711	22%	0.22	S	C	*	.	S	Bend	trans	-120.1	120.1	178.8	-61.2	-43.3	0	0	0	108.1
249	S	68.6	Low	82.4	Confident	62 Å²	62	49.6 Å²	49.6	43%	0.434	24%	0.235	S	C	.	.			trans	-95.4	126.3	177.4	138.9	0	0	0	0	109.9	E246 D254	E246-S249 WeakPolarHBondContact OE1-CA 3.45Å; S249-D254 WeakPolarHBondContact CB-OD2 3.31Å; S249-D254 PolarHBondContact OG-OD2 2.86Å
250	I	76.8	Confident	82.3	Confident	68 Å²	68	49.7 Å²	49.7	35%	0.349	24%	0.236	S	C	.	.			trans	-97.9	121.5	169.2	-59.2	-170	0	0	0	108.3	Q122 E252 Y253 D254	Q122-I250 VanDerWaalsContact NE2-CD1 3.25Å; I250-E252 HydrophobicContact CG2-CB 4.48Å; I250-E252 VanDerWaalsContact CG2-OE2 3.26Å; I250-E252 WeakPolarHBondContact CG2-OE2 3.46Å; I250-E252 PolarHBondContact O-N 3.22Å; I250-E252 VanDerWaalsContact O-N 3.14Å; I250-Y253 HydrophobicContact CB-CD2 3.86Å; I250-Y253 HydrophobicContact CD1-CD2 4.41Å; I250-Y253 HydrophobicContact CG2-CD2 3.79Å; I250-Y253 HydrophobicContact CG2-CE2 4.41Å; I250-Y253 PolarHBondContact O-N 3.45Å; I250-D254 PolarHBondContact O-N 3.48Å
251	K	77.7	Confident	82.3	Confident	104 Å²	104	49.8 Å²	49.8	45%	0.452	24%	0.236	S	C	.	.	H	α-helix	trans	-54.5	-38.2	-172.3	-64.7	-175.8	-179.4	-176.7	0	113.2	D254 F255	K251-D254 PolarHBondContact O-N 3.23Å; K251-F255 WeakPolarHBondContact O-CB 3.48Å; K251-F255 PolarHBondContact O-N 3.06Å
252	E	81.3	Confident	82	Confident	111 Å²	111	50.9 Å²	50.9	52%	0.519	24%	0.244	S	C	.	.	H	α-helix	trans	-65.3	-41.9	178.6	-68.5	77.7	-171.7	0	0	112.5	I250 F255 L256	I250-E252 HydrophobicContact CG2-CB 4.48Å; I250-E252 VanDerWaalsContact CG2-OE2 3.26Å; I250-E252 WeakPolarHBondContact CG2-OE2 3.46Å; I250-E252 PolarHBondContact O-N 3.22Å; I250-E252 VanDerWaalsContact O-N 3.14Å; E252-F255 PolarHBondContact O-N 2.82Å; E252-L256 WeakPolarHBondContact O-CB 3.25Å; E252-L256 PolarHBondContact O-N 3.22Å
253	Y	82.8	Confident	82	Confident	29 Å²	29	54.4 Å²	54.4	11%	0.114	26%	0.259	C	S	.	.	H	α-helix	trans	-73.1	-35.5	178.1	-73.9	-80.1	0	0	0	111.6	I71 Q122 I250 L256 K257	I71-Y253 HydrophobicContact CD1-CE1 4.16Å; Q122-Y253 VanDerWaalsContact NE2-CD2 3.33Å; I250-Y253 HydrophobicContact CB-CD2 3.86Å; I250-Y253 HydrophobicContact CD1-CD2 4.41Å; I250-Y253 HydrophobicContact CG2-CD2 3.79Å; I250-Y253 HydrophobicContact CG2-CE2 4.41Å; I250-Y253 PolarHBondContact O-N 3.45Å; Y253-L256 PolarHBondContact O-N 3.21Å; Y253-K257 WeakPolarHBondContact O-CB 2.95Å; Y253-K257 PolarHBondContact O-N 3.14Å
254	D	80.7	Confident	82.3	Confident	5 Å²	5	54.2 Å²	54.2	3%	0.027	26%	0.258	C	S	.	.	H	α-helix	trans	-61.7	-45.1	171.5	-90.4	-14	0	0	0	112.1	S249 I250 K251 L256 K257 T258	S249-D254 WeakPolarHBondContact CB-OD2 3.31Å; S249-D254 PolarHBondContact OG-OD2 2.86Å; I250-D254 PolarHBondContact O-N 3.48Å; K251-D254 PolarHBondContact O-N 3.23Å; D254-L256 VanDerWaalsContact C-N 3.34Å; D254-L256 PolarHBondContact O-N 2.87Å; D254-K257 WeakPolarHBondContact O-CB 3.49Å; D254-K257 PolarHBondContact O-N 3.42Å; D254-K257 WeakPolarHBondContact OD1-CE 3.3Å; D254-K257 IonicContact OD1-NZ 3.89Å; D254-K257 PolarHBondContact OD1-NZ 3.33Å; D254-T258 WeakPolarHBondContact O-CB 3.32Å; D254-T258 PolarHBondContact O-N 2.96Å; D254-T258 PolarHBondContact O-OG1 3.07Å
255	F	84.2	Confident	82.5	Confident	74 Å²	74	51.8 Å²	51.8	33%	0.325	25%	0.245	S	C	.	.	H	α-helix	trans	-61	-44.1	175.2	179.2	-105.5	0	0	0	111.7	L176 K251 E252 T258 I259	L176-F255 HydrophobicContact CD1-CB 4.07Å; L176-F255 HydrophobicContact CD1-CD2 3.56Å; L176-F255 HydrophobicContact CD1-CG 4.3Å; L176-F255 HydrophobicContact CD2-CD2 3.79Å; L176-F255 HydrophobicContact CD2-CE2 3.94Å; L176-F255 HydrophobicContact CG-CD2 4.29Å; K251-F255 WeakPolarHBondContact O-CB 3.48Å; K251-F255 PolarHBondContact O-N 3.06Å; E252-F255 PolarHBondContact O-N 2.82Å; F255-T258 PolarHBondContact O-N 3.42Å; F255-I259 HydrophobicContact CD1-CD1 3.76Å; F255-I259 HydrophobicContact CE1-CD1 3.24Å; F255-I259 HydrophobicContact CE1-CG1 4.38Å; F255-I259 HydrophobicContact CE2-CD1 4.12Å; F255-I259 HydrophobicContact CG-CD1 4.41Å; F255-I259 HydrophobicContact CZ-CD1 3.45Å; F255-I259 VanDerWaalsContact CZ-CD1 3.45Å; F255-I259 HydrophobicContact CZ-CG1 4.34Å; F255-I259 WeakPolarHBondContact O-CG1 3.19Å; F255-I259 PolarHBondContact O-N 3.07Å
256	L	87	Confident	82.6	Confident	0 Å²	0	50.9 Å²	50.9	0%	0	25%	0.25	C	C	.	.	H	α-helix	trans	-63.9	-43.6	177	-176.9	68.9	0	0	0	112.1	M74 Y75 I119 E252 Y253 D254 I259 F260	M74-L256 HydrophobicContact CB-CD1 4.35Å; M74-L256 HydrophobicContact CB-CD2 3.64Å; M74-L256 HydrophobicContact CE-CD2 3.51Å; M74-L256 HydrophobicContact CG-CD2 4.05Å; Y75-L256 HydrophobicContact CD1-CD1 3.87Å; Y75-L256 HydrophobicContact CE1-CD1 3.78Å; I119-L256 HydrophobicContact CD1-CD2 4.34Å; I119-L256 HydrophobicContact CD1-CG 4.35Å; I119-L256 HydrophobicContact CG1-CD2 4.04Å; I119-L256 HydrophobicContact CG1-CG 4.48Å; E252-L256 WeakPolarHBondContact O-CB 3.25Å; E252-L256 PolarHBondContact O-N 3.22Å; Y253-L256 PolarHBondContact O-N 3.21Å; D254-L256 VanDerWaalsContact C-N 3.34Å; D254-L256 PolarHBondContact O-N 2.87Å; L256-I259 PolarHBondContact O-N 2.95Å; L256-F260 VanDerWaalsContact O-CB 3.3Å; L256-F260 WeakPolarHBondContact O-CB 3.42Å; L256-F260 PolarHBondContact O-N 3.14Å
257	K	87.5	Confident	83	Confident	4 Å²	4	50.3 Å²	50.3	2%	0.017	25%	0.248	C	C	.	.	H	α-helix	trans	-57	-47.8	174.5	178.6	172.3	64.1	-162.5	0	110.8	I119 L239 T243 E246 Y253 D254 F260 L261	I119-K257 HydrophobicContact CG2-CB 3.96Å; I119-K257 HydrophobicContact CG2-CD 4.18Å; I119-K257 HydrophobicContact CG2-CG 4.26Å; L239-K257 HydrophobicContact CD1-CD 4.16Å; L239-K257 HydrophobicContact CD1-CG 4.28Å; L239-K257 HydrophobicContact CD2-CG 4.22Å; L239-K257 HydrophobicContact CG-CD 4.45Å; L239-K257 HydrophobicContact CG-CG 4.27Å; T243-K257 VanDerWaalsContact CG2-NZ 3.29Å; T243-K257 WeakPolarHBondContact OG1-CD 3.42Å; T243-K257 PolarHBondContact OG1-NZ 3.06Å; E246-K257 IonicContact OE2-NZ 2.69Å; E246-K257 PolarHBondContact OE2-NZ 3.28Å; Y253-K257 WeakPolarHBondContact O-CB 2.95Å; Y253-K257 PolarHBondContact O-N 3.14Å; D254-K257 WeakPolarHBondContact O-CB 3.49Å; D254-K257 PolarHBondContact O-N 3.42Å; D254-K257 WeakPolarHBondContact OD1-CE 3.3Å; D254-K257 IonicContact OD1-NZ 3.89Å; D254-K257 PolarHBondContact OD1-NZ 3.33Å; K257-F260 PolarHBondContact O-N 3.41Å; K257-L261 HydrophobicContact CG-CD1 3.99Å; K257-L261 WeakPolarHBondContact O-CB 3.46Å; K257-L261 VanDerWaalsContact O-CG 3.29Å; K257-L261 WeakPolarHBondContact O-CG 3.09Å; K257-L261 PolarHBondContact O-N 3.45Å
258	T	84.7	Confident	83.7	Confident	10 Å²	10	40.3 Å²	40.3	6%	0.061	21%	0.21	C	C	.	.	H	α-helix	trans	-57.6	-51.1	175.3	-71.9	0	0	0	0	111.7	P172 L176 D254 F255 F260 L261 V262	P172-T258 HydrophobicContact CB-CG2 3.71Å; P172-T258 VanDerWaalsContact O-CG2 3.23Å; P172-T258 WeakPolarHBondContact O-CG2 3.18Å; L176-T258 HydrophobicContact CB-CG2 4.25Å; D254-T258 WeakPolarHBondContact O-CB 3.32Å; D254-T258 PolarHBondContact O-N 2.96Å; D254-T258 PolarHBondContact O-OG1 3.07Å; F255-T258 PolarHBondContact O-N 3.42Å; T258-F260 VanDerWaalsContact C-N 3.31Å; T258-F260 PolarHBondContact O-N 2.57Å; T258-L261 PolarHBondContact O-N 2.72Å; T258-V262 HydrophobicContact CG2-CG2 4.49Å; T258-V262 WeakPolarHBondContact O-CG2 3.27Å; T258-V262 PolarHBondContact O-N 3.19Å
259	I	86.7	Confident	84.1	Confident	68 Å²	68	36.4 Å²	36.4	35%	0.349	19%	0.185	S	C	.	.	H	α-helix	trans	-58.6	-46.7	178.8	-72.6	173.3	0	0	0	110.7	F255 L256 L261 V262 F263	F255-I259 HydrophobicContact CD1-CD1 3.76Å; F255-I259 HydrophobicContact CE1-CD1 3.24Å; F255-I259 HydrophobicContact CE1-CG1 4.38Å; F255-I259 HydrophobicContact CE2-CD1 4.12Å; F255-I259 HydrophobicContact CG-CD1 4.41Å; F255-I259 HydrophobicContact CZ-CD1 3.45Å; F255-I259 VanDerWaalsContact CZ-CD1 3.45Å; F255-I259 HydrophobicContact CZ-CG1 4.34Å; F255-I259 WeakPolarHBondContact O-CG1 3.19Å; F255-I259 PolarHBondContact O-N 3.07Å; L256-I259 PolarHBondContact O-N 2.95Å; I259-L261 PolarHBondContact O-N 3.17Å; I259-V262 PolarHBondContact O-N 3.29Å; I259-F263 WeakPolarHBondContact O-CB 3.28Å; I259-F263 PolarHBondContact O-N 3Å
260	F	90.3	Very high	84.8	Confident	4 Å²	4	37.5 Å²	37.5	2%	0.018	18%	0.183	C	C	.	.	H	α-helix	trans	-61.9	-43.5	-179	-177.5	-102.4	0	0	0	111.6	H112 I115 V116 L239 L256 K257 T258 N264	H112-F260 AromaticContact CE1-CE1 3.98Å; H112-F260 AromaticContact CE1-CE2 3.81Å; H112-F260 AromaticContact CE1-CZ 3.18Å; H112-F260 WeakPolarHBondContact CE1-CZ 3.07Å; H112-F260 AromaticContact ND1-CE2 3.77Å; H112-F260 AromaticContact ND1-CZ 3.49Å; H112-F260 WeakPolarHBondContact ND1-CZ 3.39Å; H112-F260 AromaticContact NE2-CZ 3.57Å; I115-F260 HydrophobicContact CB-CD2 4.4Å; I115-F260 HydrophobicContact CB-CE2 3.94Å; I115-F260 HydrophobicContact CB-CZ 4.36Å; I115-F260 HydrophobicContact CD1-CD2 4.32Å; I115-F260 HydrophobicContact CD1-CE2 3.83Å; I115-F260 HydrophobicContact CG1-CE2 4.49Å; I115-F260 HydrophobicContact CG2-CD2 3.5Å; I115-F260 HydrophobicContact CG2-CE2 3.5Å; I115-F260 HydrophobicContact CG2-CG 4.03Å; I115-F260 HydrophobicContact CG2-CZ 4.04Å; V116-F260 HydrophobicContact CG2-CE1 3.74Å; V116-F260 HydrophobicContact CG2-CZ 3.87Å; L239-F260 HydrophobicContact CD2-CD1 3.66Å; L239-F260 HydrophobicContact CD2-CE1 3.98Å; L256-F260 VanDerWaalsContact O-CB 3.3Å; L256-F260 WeakPolarHBondContact O-CB 3.42Å; L256-F260 PolarHBondContact O-N 3.14Å; K257-F260 PolarHBondContact O-N 3.41Å; T258-F260 VanDerWaalsContact C-N 3.31Å; T258-F260 PolarHBondContact O-N 2.57Å; F260-N264 WeakPolarHBondContact CD2-ND2 3.35Å; F260-N264 WeakPolarHBondContact CE1-ND2 3.13Å; F260-N264 VanDerWaalsContact CE2-ND2 3.27Å; F260-N264 WeakPolarHBondContact CE2-ND2 3.17Å; F260-N264 VanDerWaalsContact CZ-ND2 3.32Å; F260-N264 WeakPolarHBondContact CZ-ND2 3.48Å; F260-N264 WeakPolarHBondContact O-CB 3.48Å; F260-N264 PolarHBondContact O-N 2.71Å; F260-N264 PolarHBondContact O-ND2 2.97Å
261	L	89.5	Confident	85	Confident	1 Å²	1	34.3 Å²	34.3	1%	0.005	17%	0.166	C	C	.	.	H	α-helix	trans	-64.9	-48.7	177	-71.3	169.4	0	0	0	111.6	P172 M192 F199 C236 L239 K257 T258 I259 F263 N264 I265	P172-L261 HydrophobicContact CG-CB 4.38Å; M192-L261 HydrophobicContact CE-CD1 3.88Å; M192-L261 HydrophobicContact SD-CD1 4.37Å; F199-L261 HydrophobicContact CE2-CD2 3.92Å; F199-L261 HydrophobicContact CZ-CD2 4.31Å; C236-L261 HydrophobicContact CB-CD2 3.99Å; L239-L261 HydrophobicContact CD2-CD2 4.07Å; L239-L261 HydrophobicContact CD2-CG 4.26Å; K257-L261 HydrophobicContact CG-CD1 3.99Å; K257-L261 WeakPolarHBondContact O-CB 3.46Å; K257-L261 VanDerWaalsContact O-CG 3.29Å; K257-L261 WeakPolarHBondContact O-CG 3.09Å; K257-L261 PolarHBondContact O-N 3.45Å; T258-L261 PolarHBondContact O-N 2.72Å; I259-L261 PolarHBondContact O-N 3.17Å; L261-F263 VanDerWaalsContact C-N 3.29Å; L261-F263 PolarHBondContact O-N 3.32Å; L261-N264 PolarHBondContact O-N 3.2Å; L261-I265 WeakPolarHBondContact O-CB 3.39Å; L261-I265 WeakPolarHBondContact O-CD1 3.28Å; L261-I265 WeakPolarHBondContact O-CG1 3.13Å; L261-I265 PolarHBondContact O-N 3.18Å
262	V	86.6	Confident	84.9	Confident	41 Å²	41	29.3 Å²	29.3	25%	0.248	15%	0.145	C	C	.	.	H	α-helix	trans	-57.2	-45.4	178.4	171.7	0	0	0	0	111	L169 P172 T258 I259 A266	L169-V262 HydrophobicContact CD2-CG1 4.29Å; P172-V262 HydrophobicContact CB-CG2 3.55Å; P172-V262 HydrophobicContact CG-CG2 3.79Å; T258-V262 HydrophobicContact CG2-CG2 4.49Å; T258-V262 WeakPolarHBondContact O-CG2 3.27Å; T258-V262 PolarHBondContact O-N 3.19Å; I259-V262 PolarHBondContact O-N 3.29Å; V262-A266 PolarHBondContact O-N 3.41Å; V262-A266 VanDerWaalsContact O-N 3.14Å
263	F	88.1	Confident	84.7	Confident	75 Å²	75	26.5 Å²	26.5	33%	0.329	13%	0.132	S	C	.	.	H	α-helix	trans	-61.2	-47.8	177.4	176.5	-98.8	0	0	0	111.7	I259 L261 A266 L267	I259-F263 WeakPolarHBondContact O-CB 3.28Å; I259-F263 PolarHBondContact O-N 3Å; L261-F263 VanDerWaalsContact C-N 3.29Å; L261-F263 PolarHBondContact O-N 3.32Å; F263-A266 PolarHBondContact O-N 3.13Å; F263-L267 HydrophobicContact CE1-CD1 3.66Å; F263-L267 HydrophobicContact CE2-CD1 4.49Å; F263-L267 HydrophobicContact CZ-CD1 3.52Å; F263-L267 WeakPolarHBondContact O-CB 3.43Å; F263-L267 PolarHBondContact O-N 2.95Å
264	N	90	Very high	84.3	Confident	0 Å²	0	26.1 Å²	26.1	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-71.5	-30.9	-178	-77.7	-66.5	0	0	0	113.5	H112 I232 C236 F260 L261 L267 V268	H112-N264 PolarHBondContact CE1-OD1 3.46Å; I232-N264 HydrophobicContact CG2-CB 3.84Å; C236-N264 VanDerWaalsContact SG-CB 3.56Å; F260-N264 WeakPolarHBondContact CD2-ND2 3.35Å; F260-N264 WeakPolarHBondContact CE1-ND2 3.13Å; F260-N264 VanDerWaalsContact CE2-ND2 3.27Å; F260-N264 WeakPolarHBondContact CE2-ND2 3.17Å; F260-N264 VanDerWaalsContact CZ-ND2 3.32Å; F260-N264 WeakPolarHBondContact CZ-ND2 3.48Å; F260-N264 WeakPolarHBondContact O-CB 3.48Å; F260-N264 PolarHBondContact O-N 2.71Å; F260-N264 PolarHBondContact O-ND2 2.97Å; L261-N264 PolarHBondContact O-N 3.2Å; N264-L267 PolarHBondContact O-N 3.29Å; N264-V268 WeakPolarHBondContact O-CB 3.3Å; N264-V268 VanDerWaalsContact O-CG2 3.31Å; N264-V268 WeakPolarHBondContact O-CG2 3.19Å; N264-V268 PolarHBondContact O-N 3.44Å
265	I	86.4	Confident	83.8	Confident	0 Å²	0	27.1 Å²	27.1	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-58.6	-50.8	169.5	-72.1	157.4	0	0	0	109.9	L168 L169 P172 F199 F202 L261 L267 Y269	L168-I265 HydrophobicContact CB-CG2 4.47Å; L168-I265 HydrophobicContact CD1-CD1 3.95Å; L168-I265 HydrophobicContact CD1-CG1 4.39Å; L168-I265 HydrophobicContact CD2-CB 4.4Å; L168-I265 HydrophobicContact CD2-CD1 4.27Å; L168-I265 HydrophobicContact CD2-CG1 3.91Å; L168-I265 HydrophobicContact CD2-CG2 3.64Å; L168-I265 HydrophobicContact CG-CD1 3.64Å; L168-I265 HydrophobicContact CG-CG1 3.85Å; L168-I265 HydrophobicContact CG-CG2 3.82Å; L169-I265 HydrophobicContact CD2-CG2 3.94Å; L169-I265 HydrophobicContact CG-CG2 4.45Å; P172-I265 HydrophobicContact CG-CD1 4.09Å; F199-I265 HydrophobicContact CE2-CG1 4.22Å; F199-I265 HydrophobicContact CZ-CG1 3.73Å; F202-I265 HydrophobicContact CE2-CG2 4.44Å; L261-I265 WeakPolarHBondContact O-CB 3.39Å; L261-I265 WeakPolarHBondContact O-CD1 3.28Å; L261-I265 WeakPolarHBondContact O-CG1 3.13Å; L261-I265 PolarHBondContact O-N 3.18Å; I265-L267 VanDerWaalsContact C-N 3.26Å; I265-L267 PolarHBondContact O-N 3.19Å; I265-Y269 WeakPolarHBondContact O-CB 3.45Å; I265-Y269 PolarHBondContact O-N 2.98Å; I265-Y269 VanDerWaalsContact O-N 3.1Å
266	A	85.2	Confident	83	Confident	49 Å²	49	25.2 Å²	25.2	41%	0.405	13%	0.129	S	C	.	.	H	α-helix	trans	-62.4	-37	177.8	0	0	0	0	0	111.7	V262 F263 F270	V262-A266 PolarHBondContact O-N 3.41Å; V262-A266 VanDerWaalsContact O-N 3.14Å; F263-A266 PolarHBondContact O-N 3.13Å; A266-F270 WeakPolarHBondContact O-CB 3.44Å; A266-F270 PolarHBondContact O-N 3.11Å
267	L	86.2	Confident	82.1	Confident	9 Å²	9	28.4 Å²	28.4	5%	0.047	15%	0.149	C	C	.	.	H	α-helix	trans	-69.5	-47.9	-179.4	-163.9	124.8	0	0	0	113.1	A85 L89 M228 I232 F263 N264 I265 Y269 F270 S271	A85-L267 HydrophobicContact CB-CD1 3.35Å; A85-L267 HydrophobicContact CB-CD2 4.05Å; A85-L267 HydrophobicContact CB-CG 4.27Å; L89-L267 HydrophobicContact CD1-CD1 4.1Å; L89-L267 HydrophobicContact CD1-CD2 4.19Å; L89-L267 HydrophobicContact CD1-CG 3.89Å; M228-L267 HydrophobicContact CE-CD2 4.13Å; I232-L267 HydrophobicContact CD1-CD2 3.3Å; F263-L267 HydrophobicContact CE1-CD1 3.66Å; F263-L267 HydrophobicContact CE2-CD1 4.49Å; F263-L267 HydrophobicContact CZ-CD1 3.52Å; F263-L267 WeakPolarHBondContact O-CB 3.43Å; F263-L267 PolarHBondContact O-N 2.95Å; N264-L267 PolarHBondContact O-N 3.29Å; I265-L267 VanDerWaalsContact C-N 3.26Å; I265-L267 PolarHBondContact O-N 3.19Å; L267-Y269 VanDerWaalsContact C-N 3.25Å; L267-Y269 PolarHBondContact O-N 3.04Å; L267-F270 PolarHBondContact O-N 3.38Å; L267-S271 VanDerWaalsContact O-CB 3.25Å; L267-S271 WeakPolarHBondContact O-CB 3.41Å; L267-S271 PolarHBondContact O-N 2.95Å
268	V	85.3	Confident	81	Confident	0 Å²	0	30.5 Å²	30.5	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-57.9	-44	174.9	169.9	0	0	0	0	109.7	F202 I232 V233 N264 S271 I272	F202-V268 HydrophobicContact CB-CG1 4.22Å; F202-V268 HydrophobicContact CD1-CG1 3.99Å; F202-V268 HydrophobicContact CD2-CG1 4.11Å; F202-V268 HydrophobicContact CE1-CG1 4.34Å; F202-V268 HydrophobicContact CE2-CG1 4.39Å; F202-V268 HydrophobicContact CG-CG1 3.9Å; I232-V268 HydrophobicContact CB-CG2 4.02Å; I232-V268 HydrophobicContact CG2-CG2 3.47Å; I232-V268 VanDerWaalsContact CG2-CG2 3.47Å; V233-V268 HydrophobicContact CG2-CG1 3.91Å; V233-V268 HydrophobicContact CG2-CG2 3.94Å; N264-V268 WeakPolarHBondContact O-CB 3.3Å; N264-V268 VanDerWaalsContact O-CG2 3.31Å; N264-V268 WeakPolarHBondContact O-CG2 3.19Å; N264-V268 PolarHBondContact O-N 3.44Å; V268-S271 WeakPolarHBondContact O-CB 3.34Å; V268-S271 PolarHBondContact O-N 3.14Å; V268-I272 HydrophobicContact CG1-CD1 3.9Å; V268-I272 WeakPolarHBondContact O-CG1 3.33Å; V268-I272 PolarHBondContact O-N 3.43Å
269	Y	81.4	Confident	79.8	Confident	50 Å²	50	32.4 Å²	32.4	20%	0.196	17%	0.17	C	C	.	.	H	α-helix	trans	-62.9	-49.2	177.1	174.9	-111.8	0	0	0	113	F161 V165 I265 L267 S271 I272 M273	F161-Y269 HydrophobicContact CD2-CD2 4.24Å; F161-Y269 AromaticContact CD2-CE2 3.5Å; F161-Y269 HydrophobicContact CD2-CE2 3.5Å; F161-Y269 VanDerWaalsContact CD2-CE2 3.5Å; F161-Y269 AromaticContact CD2-CZ 3.8Å; F161-Y269 HydrophobicContact CE1-CE1 4.47Å; F161-Y269 HydrophobicContact CE2-CD1 4.2Å; F161-Y269 AromaticContact CE2-CD2 3.43Å; F161-Y269 HydrophobicContact CE2-CD2 3.43Å; F161-Y269 VanDerWaalsContact CE2-CD2 3.43Å; F161-Y269 AromaticContact CE2-CE1 3.72Å; F161-Y269 HydrophobicContact CE2-CE1 3.72Å; F161-Y269 AromaticContact CE2-CE2 2.89Å; F161-Y269 HydrophobicContact CE2-CE2 2.89Å; F161-Y269 HydrophobicContact CE2-CG 4.05Å; F161-Y269 AromaticContact CE2-CZ 3.01Å; F161-Y269 VanDerWaalsContact CE2-OH 3.26Å; F161-Y269 WeakPolarHBondContact CE2-OH 3.48Å; F161-Y269 HydrophobicContact CZ-CD1 4.13Å; F161-Y269 HydrophobicContact CZ-CD2 4.19Å; F161-Y269 AromaticContact CZ-CE1 3.48Å; F161-Y269 HydrophobicContact CZ-CE1 3.48Å; F161-Y269 VanDerWaalsContact CZ-CE1 3.48Å; F161-Y269 AromaticContact CZ-CE2 3.6Å; F161-Y269 HydrophobicContact CZ-CE2 3.6Å; F161-Y269 HydrophobicContact CZ-CG 4.42Å; F161-Y269 AromaticContact CZ-CZ 3.14Å; F161-Y269 WeakPolarHBondContact CZ-OH 3.34Å; V165-Y269 HydrophobicContact CG2-CD2 4.44Å; I265-Y269 WeakPolarHBondContact O-CB 3.45Å; I265-Y269 PolarHBondContact O-N 2.98Å; I265-Y269 VanDerWaalsContact O-N 3.1Å; L267-Y269 VanDerWaalsContact C-N 3.25Å; L267-Y269 PolarHBondContact O-N 3.04Å; Y269-S271 PolarHBondContact O-N 3Å; Y269-I272 PolarHBondContact O-N 2.99Å; Y269-I272 VanDerWaalsContact O-N 3.13Å; Y269-M273 HydrophobicContact CD1-CG 4.4Å; Y269-M273 HydrophobicContact CD2-CG 4.23Å; Y269-M273 HydrophobicContact CE1-CG 3.8Å; Y269-M273 HydrophobicContact CE2-CG 3.54Å; Y269-M273 HydrophobicContact CE2-SD 3.85Å; Y269-M273 WeakPolarHBondContact O-CG 3.49Å; Y269-M273 PolarHBondContact O-N 2.85Å; Y269-M273 PolarHBondContact OH-SD 3.22Å
270	F	82.2	Confident	78.8	Confident	85 Å²	85	34.4 Å²	34.4	37%	0.373	18%	0.176	S	C	.	.	H	α-helix	trans	-59.7	-36.4	178.4	-175.8	-113	0	0	0	111.5	L89 K90 A266 L267 M273 I274	L89-F270 HydrophobicContact CB-CD1 4.43Å; L89-F270 HydrophobicContact CB-CE1 4.22Å; L89-F270 HydrophobicContact CD1-CD1 4.1Å; K90-F270 HydrophobicContact CG-CE1 4.36Å; A266-F270 WeakPolarHBondContact O-CB 3.44Å; A266-F270 PolarHBondContact O-N 3.11Å; L267-F270 PolarHBondContact O-N 3.38Å; F270-M273 PolarHBondContact O-N 3.15Å; F270-I274 HydrophobicContact CD1-CD1 3.57Å; F270-I274 HydrophobicContact CE1-CD1 3.15Å; F270-I274 HydrophobicContact CE1-CG1 4.17Å; F270-I274 HydrophobicContact CE2-CD1 4.26Å; F270-I274 HydrophobicContact CE2-CG1 4.47Å; F270-I274 HydrophobicContact CG-CD1 4.28Å; F270-I274 HydrophobicContact CZ-CD1 3.54Å; F270-I274 HydrophobicContact CZ-CG1 4.13Å; F270-I274 WeakPolarHBondContact O-CG1 3.08Å; F270-I274 PolarHBondContact O-N 3.38Å
271	S	80.7	Confident	77.6	Confident	1 Å²	1	37.5 Å²	37.5	1%	0.007	20%	0.198	C	C	.	.	H	α-helix	trans	-65	-43.4	175	-163	0	0	0	0	112.8	L89 L225 Q229 L267 V268 Y269 M273 I274 N275	L89-S271 VanDerWaalsContact CD2-CB 3.48Å; L89-S271 VanDerWaalsContact CD2-OG 3.24Å; L89-S271 WeakPolarHBondContact CD2-OG 3.41Å; L225-S271 WeakPolarHBondContact CD1-OG 3.27Å; Q229-S271 WeakPolarHBondContact CG-OG 3.44Å; Q229-S271 VanDerWaalsContact NE2-CB 3.34Å; Q229-S271 PolarHBondContact NE2-O 3.43Å; Q229-S271 PolarHBondContact NE2-OG 3.31Å; L267-S271 VanDerWaalsContact O-CB 3.25Å; L267-S271 WeakPolarHBondContact O-CB 3.41Å; L267-S271 PolarHBondContact O-N 2.95Å; V268-S271 WeakPolarHBondContact O-CB 3.34Å; V268-S271 PolarHBondContact O-N 3.14Å; Y269-S271 PolarHBondContact O-N 3Å; S271-M273 VanDerWaalsContact C-N 3.33Å; S271-M273 PolarHBondContact O-N 2.79Å; S271-I274 PolarHBondContact O-N 3.43Å; S271-N275 PolarHBondContact O-N 2.88Å
272	I	77	Confident	76.1	Confident	0 Å²	0	39.9 Å²	39.9	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-60.8	-43.1	173.8	-71.3	164.9	0	0	0	110.9	F202 M205 T209 V268 Y269 N275 E276	F202-I272 HydrophobicContact CD1-CD1 4Å; F202-I272 HydrophobicContact CE1-CD1 4.24Å; M205-I272 HydrophobicContact CB-CD1 4.23Å; T209-I272 HydrophobicContact CG2-CG2 4.1Å; V268-I272 HydrophobicContact CG1-CD1 3.9Å; V268-I272 WeakPolarHBondContact O-CG1 3.33Å; V268-I272 PolarHBondContact O-N 3.43Å; Y269-I272 PolarHBondContact O-N 2.99Å; Y269-I272 VanDerWaalsContact O-N 3.13Å; I272-N275 PolarHBondContact O-N 3.08Å; I272-E276 PolarHBondContact O-N 2.85Å
273	M	76.8	Confident	74.7	Confident	52 Å²	52	41.4 Å²	41.4	26%	0.256	22%	0.215	S	C	.	.	H	α-helix	trans	-64.3	-40.2	177.4	-73	-65.7	-60.4	0	0	112.8	Y158 Y269 F270 S271 E276 T277	Y158-M273 HydrophobicContact CE1-SD 3.73Å; Y269-M273 HydrophobicContact CD1-CG 4.4Å; Y269-M273 HydrophobicContact CD2-CG 4.23Å; Y269-M273 HydrophobicContact CE1-CG 3.8Å; Y269-M273 HydrophobicContact CE2-CG 3.54Å; Y269-M273 HydrophobicContact CE2-SD 3.85Å; Y269-M273 WeakPolarHBondContact O-CG 3.49Å; Y269-M273 PolarHBondContact O-N 2.85Å; Y269-M273 PolarHBondContact OH-SD 3.22Å; F270-M273 PolarHBondContact O-N 3.15Å; S271-M273 VanDerWaalsContact C-N 3.33Å; S271-M273 PolarHBondContact O-N 2.79Å; M273-E276 PolarHBondContact O-N 2.88Å; M273-T277 WeakPolarHBondContact O-CB 3.4Å; M273-T277 WeakPolarHBondContact O-CG2 3.15Å; M273-T277 PolarHBondContact O-N 3.44Å; M273-T277 PolarHBondContact O-OG1 2.95Å
274	I	74.5	Confident	73.6	Confident	20 Å²	20	46.6 Å²	46.6	10%	0.103	23%	0.232	C	C	.	.	H	α-helix	trans	-63.6	-47.4	175.4	-73.9	164.1	0	0	0	110.3	L89 L225 F270 S271 E276 T277 N278	L89-I274 HydrophobicContact CB-CD1 3.79Å; L89-I274 HydrophobicContact CD2-CD1 3.92Å; L89-I274 HydrophobicContact CG-CD1 4.46Å; L89-I274 WeakPolarHBondContact O-CD1 3.18Å; L225-I274 HydrophobicContact CD2-CG2 4.48Å; F270-I274 HydrophobicContact CD1-CD1 3.57Å; F270-I274 HydrophobicContact CE1-CD1 3.15Å; F270-I274 HydrophobicContact CE1-CG1 4.17Å; F270-I274 HydrophobicContact CE2-CD1 4.26Å; F270-I274 HydrophobicContact CE2-CG1 4.47Å; F270-I274 HydrophobicContact CG-CD1 4.28Å; F270-I274 HydrophobicContact CZ-CD1 3.54Å; F270-I274 HydrophobicContact CZ-CG1 4.13Å; F270-I274 WeakPolarHBondContact O-CG1 3.08Å; F270-I274 PolarHBondContact O-N 3.38Å; S271-I274 PolarHBondContact O-N 3.43Å; I274-E276 PolarHBondContact O-N 3.15Å; I274-T277 WeakPolarHBondContact CA-OG1 3.35Å; I274-T277 PolarHBondContact O-N 3.1Å; I274-T277 PolarHBondContact O-OG1 3.4Å; I274-N278 WeakPolarHBondContact CG2-ND2 3.37Å; I274-N278 WeakPolarHBondContact O-CB 3.36Å; I274-N278 PolarHBondContact O-N 2.96Å
275	N	69	Low	72.4	Confident	27 Å²	27	49 Å²	49	14%	0.144	25%	0.249	C	C	.	.	H	α-helix	trans	-53.6	-45.4	176.8	-79.1	0.7	0	0	0	111	L225 Q229 S271 I272 L279	L225-N275 WeakPolarHBondContact CD2-OD1 3.49Å; Q229-N275 PolarHBondContact NE2-ND2 2.91Å; Q229-N275 PolarHBondContact OE1-ND2 3.36Å; S271-N275 PolarHBondContact O-N 2.88Å; I272-N275 PolarHBondContact O-N 3.08Å; N275-L279 WeakPolarHBondContact O-CB 3.46Å; N275-L279 PolarHBondContact O-N 3.31Å
276	E	67.2	Low	71.2	Confident	34 Å²	34	53.1 Å²	53.1	16%	0.159	27%	0.271	C	S	.	.	H	α-helix	trans	-72	-39.3	-179.3	-157.6	-150.9	-170.7	0	0	113.6	Y158 I272 M273 I274 L279 K280	Y158-E276 WeakPolarHBondContact CE1-OE2 3.28Å; Y158-E276 HydrophobicContact CE2-CG 4.07Å; Y158-E276 WeakPolarHBondContact CE2-OE1 3.42Å; Y158-E276 VanDerWaalsContact CZ-OE2 3.23Å; Y158-E276 VanDerWaalsContact OH-CB 3.25Å; Y158-E276 WeakPolarHBondContact OH-CB 3.4Å; Y158-E276 WeakPolarHBondContact OH-CG 3.38Å; Y158-E276 PolarHBondContact OH-OE2 3.25Å; I272-E276 PolarHBondContact O-N 2.85Å; M273-E276 PolarHBondContact O-N 2.88Å; I274-E276 PolarHBondContact O-N 3.15Å; E276-L279 WeakPolarHBondContact O-CA 3.24Å; E276-L279 WeakPolarHBondContact O-CB 3.27Å; E276-L279 PolarHBondContact O-N 2.77Å; E276-K280 VanDerWaalsContact CD-CE 3.49Å; E276-K280 PolarHBondContact O-N 2.82Å; E276-K280 WeakPolarHBondContact OE1-CE 3.28Å; E276-K280 IonicContact OE1-NZ 2.86Å; E276-K280 PolarHBondContact OE1-NZ 2.65Å; E276-K280 IonicContact OE2-NZ 2.77Å; E276-K280 PolarHBondContact OE2-NZ 2.84Å
277	T	69.1	Low	69.9	Low	66 Å²	66	56.8 Å²	56.8	41%	0.405	28%	0.281	S	S	.	.	H	α-helix	trans	-68.2	-41	178.5	51	0	0	0	0	111.9	M273 I274 L279 K280 S281	M273-T277 WeakPolarHBondContact O-CB 3.4Å; M273-T277 WeakPolarHBondContact O-CG2 3.15Å; M273-T277 PolarHBondContact O-N 3.44Å; M273-T277 PolarHBondContact O-OG1 2.95Å; I274-T277 WeakPolarHBondContact CA-OG1 3.35Å; I274-T277 PolarHBondContact O-N 3.1Å; I274-T277 PolarHBondContact O-OG1 3.4Å; T277-L279 VanDerWaalsContact C-N 3.26Å; T277-L279 PolarHBondContact O-N 3.24Å; T277-K280 PolarHBondContact O-N 3.22Å; T277-S281 WeakPolarHBondContact O-CB 3.44Å; T277-S281 PolarHBondContact O-N 2.86Å; T277-S281 PolarHBondContact O-OG 3.28Å
278	N	65.2	Low	68.9	Low	49 Å²	49	60.6 Å²	60.6	26%	0.262	30%	0.301	S	S	.	.	H	α-helix	trans	-57.4	-43.6	170.2	-73.6	-14.5	0	0	0	109.9	I274 S281 K282	I274-N278 WeakPolarHBondContact CG2-ND2 3.37Å; I274-N278 WeakPolarHBondContact O-CB 3.36Å; I274-N278 PolarHBondContact O-N 2.96Å; N278-S281 PolarHBondContact O-OG 3.39Å; N278-K282 WeakPolarHBondContact O-CG 3.14Å; N278-K282 PolarHBondContact O-N 3.03Å
279	L	59.5	Low	67.8	Low	49 Å²	49	69.7 Å²	69.7	26%	0.257	34%	0.336	S	S	.	.	H	α-helix	trans	-56.9	-54.1	174.3	-144.3	73	0	0	0	113.3	V216 N275 E276 T277 S281 K282 L283	V216-L279 HydrophobicContact CB-CD1 4.47Å; V216-L279 HydrophobicContact CG1-CD1 3.23Å; V216-L279 HydrophobicContact CG1-CD2 4.19Å; V216-L279 HydrophobicContact CG1-CG 3.63Å; N275-L279 WeakPolarHBondContact O-CB 3.46Å; N275-L279 PolarHBondContact O-N 3.31Å; E276-L279 WeakPolarHBondContact O-CA 3.24Å; E276-L279 WeakPolarHBondContact O-CB 3.27Å; E276-L279 PolarHBondContact O-N 2.77Å; T277-L279 VanDerWaalsContact C-N 3.26Å; T277-L279 PolarHBondContact O-N 3.24Å; L279-S281 VanDerWaalsContact C-N 3.34Å; L279-S281 PolarHBondContact O-N 3.46Å; L279-K282 PolarHBondContact O-N 2.76Å; L279-L283 PolarHBondContact O-N 3.38Å
280	K	65.4	Low	67	Low	110 Å²	110	74.2 Å²	74.2	48%	0.478	36%	0.362	S	S	.	.	H	α-helix	trans	-63.4	-39.1	-177.1	-77.3	174.2	179	158.9	0	112	E276 T277 K282 R284	E276-K280 VanDerWaalsContact CD-CE 3.49Å; E276-K280 PolarHBondContact O-N 2.82Å; E276-K280 WeakPolarHBondContact OE1-CE 3.28Å; E276-K280 IonicContact OE1-NZ 2.86Å; E276-K280 PolarHBondContact OE1-NZ 2.65Å; E276-K280 IonicContact OE2-NZ 2.77Å; E276-K280 PolarHBondContact OE2-NZ 2.84Å; T277-K280 PolarHBondContact O-N 3.22Å; K280-K282 VanDerWaalsContact C-N 3.32Å; K280-K282 PolarHBondContact O-N 3.01Å; K280-R284 PolarHBondContact O-N 2.84Å
281	S	64.1	Low	66	Low	69 Å²	69	75 Å²	75	48%	0.483	37%	0.374	S	S	.	.	H	α-helix	trans	-63.1	-39.4	177.7	75.7	0	0	0	0	111.8	T277 N278 L279 R284 S285	T277-S281 WeakPolarHBondContact O-CB 3.44Å; T277-S281 PolarHBondContact O-N 2.86Å; T277-S281 PolarHBondContact O-OG 3.28Å; N278-S281 PolarHBondContact O-OG 3.39Å; L279-S281 VanDerWaalsContact C-N 3.34Å; L279-S281 PolarHBondContact O-N 3.46Å; S281-R284 PolarHBondContact O-N 2.96Å; S281-S285 PolarHBondContact O-N 2.96Å; S281-S285 VanDerWaalsContact O-N 3.14Å
282	K	59.2	Low	64.6	Low	52 Å²	52	85.4 Å²	85.4	23%	0.226	42%	0.422	C	S	.	.	H	α-helix	trans	-70.6	-44.4	178.9	-70.6	179.6	-171.2	-172.2	0	112.2	E219 N278 L279 K280 R284 S285 N286	E219-K282 IonicContact OE1-NZ 3.07Å; E219-K282 PolarHBondContact OE1-NZ 3.33Å; E219-K282 IonicContact OE2-NZ 3.84Å; E219-K282 PolarHBondContact OE2-NZ 2.88Å; E219-K282 VanDerWaalsContact OE2-NZ 3.07Å; N278-K282 WeakPolarHBondContact O-CG 3.14Å; N278-K282 PolarHBondContact O-N 3.03Å; L279-K282 PolarHBondContact O-N 2.76Å; K280-K282 VanDerWaalsContact C-N 3.32Å; K280-K282 PolarHBondContact O-N 3.01Å; K282-R284 VanDerWaalsContact C-N 3.26Å; K282-R284 PolarHBondContact O-N 3.04Å; K282-S285 WeakPolarHBondContact O-CA 3.44Å; K282-S285 WeakPolarHBondContact O-CB 3.45Å; K282-S285 PolarHBondContact O-N 2.96Å; K282-S285 PolarHBondContact O-OG 2.99Å; K282-N286 PolarHBondContact O-N 3.31Å
283	L	56.6	Low	63.9	Low	72 Å²	72	89.7 Å²	89.7	38%	0.377	44%	0.443	S	S	.	.	H	α-helix	trans	-53.9	-44.4	174.1	-77.7	170.6	0	0	0	111.8	V216 L279 S285 N286 M287	V216-L283 HydrophobicContact CG2-CD2 4.34Å; L279-L283 PolarHBondContact O-N 3.38Å; L283-S285 VanDerWaalsContact C-N 3.34Å; L283-S285 PolarHBondContact O-N 3.39Å; L283-N286 PolarHBondContact O-N 3.13Å; L283-M287 PolarHBondContact O-N 3.1Å
284	R	65.4	Low	63.3	Low	185 Å²	185	91.7 Å²	91.7	70%	0.698	45%	0.453	S	S	*	.	H	α-helix	trans	-63	-39.8	175.9	-171.5	-179.6	-73.4	-175	-3.5	112.1	K280 S281 K282 N288	K280-R284 PolarHBondContact O-N 2.84Å; S281-R284 PolarHBondContact O-N 2.96Å; K282-R284 VanDerWaalsContact C-N 3.26Å; K282-R284 PolarHBondContact O-N 3.04Å; R284-N288 VanDerWaalsContact O-CG 3.25Å; R284-N288 PolarHBondContact O-N 3.19Å; R284-N288 VanDerWaalsContact O-N 3.11Å; R284-N288 PolarHBondContact O-OD1 3.4Å
285	S	64.7	Low	62.6	Low	50 Å²	50	95.7 Å²	95.7	35%	0.35	47%	0.472	S	S	.	.	H	α-helix	trans	-67.5	-36.9	178.4	78.6	0	0	0	0	113.2	S281 K282 L283 N288 R289	S281-S285 PolarHBondContact O-N 2.96Å; S281-S285 VanDerWaalsContact O-N 3.14Å; K282-S285 WeakPolarHBondContact O-CA 3.44Å; K282-S285 WeakPolarHBondContact O-CB 3.45Å; K282-S285 PolarHBondContact O-N 2.96Å; K282-S285 PolarHBondContact O-OG 2.99Å; L283-S285 VanDerWaalsContact C-N 3.34Å; L283-S285 PolarHBondContact O-N 3.39Å; S285-N288 PolarHBondContact O-N 3.45Å; S285-R289 PolarHBondContact O-N 3.04Å
286	N	60.4	Low	62.3	Low	86 Å²	86	99.7 Å²	99.7	46%	0.46	49%	0.492	S	S	.	.	H	α-helix	trans	-70.7	-42.2	176.7	-78.5	-7.7	0	0	0	111.5	K282 L283 N288 R289 I290	K282-N286 PolarHBondContact O-N 3.31Å; L283-N286 PolarHBondContact O-N 3.13Å; N286-N288 VanDerWaalsContact C-N 3.28Å; N286-N288 PolarHBondContact O-N 3.16Å; N286-R289 PolarHBondContact O-N 3.28Å; N286-R289 VanDerWaalsContact O-N 3.08Å; N286-I290 WeakPolarHBondContact O-CG1 3.43Å; N286-I290 PolarHBondContact O-N 3.16Å; N286-I290 VanDerWaalsContact O-N 3.1Å
287	M	58.7	Low	62	Low	127 Å²	127	103.8 Å²	103.8	63%	0.626	51%	0.513	S	S	*	.	H	α-helix	trans	-58.4	-40	172.6	-79.9	-177.6	63	0	0	112.5	L283 R289 I290 T291	L283-M287 PolarHBondContact O-N 3.1Å; M287-R289 VanDerWaalsContact C-N 3.3Å; M287-R289 PolarHBondContact O-N 3.1Å; M287-I290 PolarHBondContact O-N 3.47Å; M287-T291 WeakPolarHBondContact O-CG2 3.47Å; M287-T291 PolarHBondContact O-N 3.28Å; M287-T291 VanDerWaalsContact O-N 3.15Å; M287-T291 PolarHBondContact O-OG1 3.41Å
288	N	64.7	Low	61.5	Low	88 Å²	88	106.3 Å²	106.3	47%	0.471	52%	0.52	S	S	.	.	H	α-helix	trans	-65.5	-31.2	176.3	-71	-4.4	0	0	0	112.5	R284 S285 N286 T291 H292	R284-N288 VanDerWaalsContact O-CG 3.25Å; R284-N288 PolarHBondContact O-N 3.19Å; R284-N288 VanDerWaalsContact O-N 3.11Å; R284-N288 PolarHBondContact O-OD1 3.4Å; S285-N288 PolarHBondContact O-N 3.45Å; N286-N288 VanDerWaalsContact C-N 3.28Å; N286-N288 PolarHBondContact O-N 3.16Å; N288-T291 WeakPolarHBondContact CA-OG1 3.4Å; N288-T291 PolarHBondContact O-OG1 3.46Å; N288-H292 PolarHBondContact O-CD2 3.29Å
289	R	61.4	Low	61.2	Low	191 Å²	191	110.4 Å²	110.4	72%	0.721	54%	0.538	S	S	*	.	H	α-helix	trans	-74.1	-29.2	173.3	-74.7	-169.7	-151	-179.4	9	113.8	S285 N286 M287 T291	S285-R289 PolarHBondContact O-N 3.04Å; N286-R289 PolarHBondContact O-N 3.28Å; N286-R289 VanDerWaalsContact O-N 3.08Å; M287-R289 VanDerWaalsContact C-N 3.3Å; M287-R289 PolarHBondContact O-N 3.1Å; R289-T291 VanDerWaalsContact C-N 3.34Å
290	I	64.6	Low	61.3	Low	145 Å²	145	115.2 Å²	115.2	74%	0.744	56%	0.56	S	S	*	*	H	α-helix	trans	-79.4	-23.6	179.9	-64.2	166.4	0	0	0	111.1	N286 M287	N286-I290 WeakPolarHBondContact O-CG1 3.43Å; N286-I290 PolarHBondContact O-N 3.16Å; N286-I290 VanDerWaalsContact O-N 3.1Å; M287-I290 PolarHBondContact O-N 3.47Å
291	T	62.7	Low	61	Low	103 Å²	103	115.6 Å²	115.6	63%	0.632	57%	0.567	S	S	*	*			trans	-91.9	-7.2	-178.8	46.9	0	0	0	0	114.4	M287 N288 R289	M287-T291 WeakPolarHBondContact O-CG2 3.47Å; M287-T291 PolarHBondContact O-N 3.28Å; M287-T291 VanDerWaalsContact O-N 3.15Å; M287-T291 PolarHBondContact O-OG1 3.41Å; N288-T291 WeakPolarHBondContact CA-OG1 3.4Å; N288-T291 PolarHBondContact O-OG1 3.46Å; R289-T291 VanDerWaalsContact C-N 3.34Å
292	H	49.7	Very low	60.7	Low	219 Å²	219	119.8 Å²	119.8	100%	1.014	57%	0.574	S	S	*	*			trans	-112.4	0	176.6	-79.3	-56.7	0	0	0	111.4	N288	N288-H292 PolarHBondContact O-CD2 3.29Å

Retrieved 292 of 292 residues in 182 ms (Link to these results)

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