A0A5K4F3P3_SCHMA Loading...

Mannosyltransferase AlphaSync

AlphaFold DB , UniProt , Accession A0A5K4F3P3, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 445 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure AlphaSync Parameters PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	61	Low	84.4	Confident	173 Å²	173	87.7 Å²	87.7	85%	0.852	44%	0.436	S	S	*	.				0	-60.6	0	-79	-82.1	-140	0	0	112.2	V3 I4 F5	M1-V3 VanDerWaalsContact C-N 3.26Å; M1-V3 PolarHBondContact O-N 3.48Å; M1-V3 VanDerWaalsContact O-N 3.12Å; M1-I4 WeakPolarHBondContact O-CB 3.45Å; M1-I4 PolarHBondContact O-N 3.47Å; M1-F5 WeakPolarHBondContact O-CD2 3.43Å; M1-F5 PolarHBondContact O-N 3.16Å; M1-F5 HydrophobicContact SD-CE2 4.15Å
2	E	74.8	Confident	85.4	Confident	82 Å²	82	85.2 Å²	85.2	38%	0.383	42%	0.42	S	S	.	.	H	α-helix	trans	-54.1	-38.2	-174.6	-63.6	-143.5	137.1	0	0	114.9	I4 F5 R6 K122	E2-I4 PolarHBondContact O-N 2.85Å; E2-F5 PolarHBondContact O-N 3.02Å; E2-F5 VanDerWaalsContact O-N 3.16Å; E2-R6 WeakPolarHBondContact O-CG 3.4Å; E2-R6 PolarHBondContact O-N 3.21Å; E2-R6 IonicContact OE2-NE 2.69Å; E2-R6 IonicContact OE2-NH2 2.8Å; E2-R6 PolarHBondContact OE2-NH2 3.32Å; E2-K122 IonicContact OE1-NZ 3.52Å; E2-K122 PolarHBondContact OE1-NZ 3.42Å
3	V	79.1	Confident	86.3	Confident	95 Å²	95	84.7 Å²	84.7	58%	0.576	43%	0.425	S	S	*	.	H	α-helix	trans	-56.7	-34.7	177.8	179.1	0	0	0	0	112.2	M1 N7	M1-V3 VanDerWaalsContact C-N 3.26Å; M1-V3 PolarHBondContact O-N 3.48Å; M1-V3 VanDerWaalsContact O-N 3.12Å; V3-N7 PolarHBondContact O-N 2.85Å
4	I	80.1	Confident	87.1	Confident	63 Å²	63	82.8 Å²	82.8	32%	0.323	42%	0.423	S	S	.	.	H	α-helix	trans	-70.8	-49.2	178.3	-61.1	173.2	0	0	0	109.4	M1 E2 R6 N7 L11 C14	M1-I4 WeakPolarHBondContact O-CB 3.45Å; M1-I4 PolarHBondContact O-N 3.47Å; E2-I4 PolarHBondContact O-N 2.85Å; I4-R6 PolarHBondContact O-N 3.42Å; I4-N7 PolarHBondContact O-N 3.39Å; I4-L11 HydrophobicContact CG2-CB 4.49Å; I4-L11 HydrophobicContact CG2-CD1 4.26Å; I4-C14 HydrophobicContact CG2-CB 4.46Å
5	F	83.9	Confident	87.9	Confident	30 Å²	30	77.9 Å²	77.9	13%	0.132	40%	0.398	C	S	.	.	H	α-helix	trans	-67.4	-33.6	-177.4	-73	-86	0	0	0	113.6	M1 E2 L11 Y109 F118 K122 L125	M1-F5 WeakPolarHBondContact O-CD2 3.43Å; M1-F5 PolarHBondContact O-N 3.16Å; M1-F5 HydrophobicContact SD-CE2 4.15Å; E2-F5 PolarHBondContact O-N 3.02Å; E2-F5 VanDerWaalsContact O-N 3.16Å; F5-L11 HydrophobicContact CD1-CD1 4.01Å; F5-L11 HydrophobicContact CD1-CD2 4.3Å; F5-L11 HydrophobicContact CE1-CD1 4.22Å; F5-Y109 HydrophobicContact CD1-CD2 4.29Å; F5-Y109 AromaticContact CD1-CE2 3.86Å; F5-Y109 HydrophobicContact CD1-CE2 3.86Å; F5-Y109 PolarHBondContact O-OH 3.42Å; F5-F118 HydrophobicContact CB-CE2 3.68Å; F5-F118 HydrophobicContact CB-CZ 3.83Å; F5-K122 HydrophobicContact CB-CD 4.08Å; F5-K122 HydrophobicContact CB-CG 3.93Å; F5-K122 HydrophobicContact CD1-CB 4.26Å; F5-K122 HydrophobicContact CD1-CD 4.46Å; F5-K122 HydrophobicContact CD1-CG 3.64Å; F5-K122 HydrophobicContact CD2-CD 4.02Å; F5-K122 HydrophobicContact CD2-CG 4.08Å; F5-K122 HydrophobicContact CE1-CB 4.16Å; F5-K122 HydrophobicContact CE1-CG 4.05Å; F5-K122 HydrophobicContact CE2-CG 4.49Å; F5-K122 HydrophobicContact CG-CD 3.96Å; F5-K122 HydrophobicContact CG-CG 3.64Å; F5-K122 HydrophobicContact CZ-CB 4.45Å; F5-K122 HydrophobicContact CZ-CG 4.47Å; F5-L125 HydrophobicContact CD1-CD2 4.42Å; F5-L125 HydrophobicContact CE1-CB 4.48Å; F5-L125 HydrophobicContact CE1-CD2 3.76Å
6	R	85.3	Confident	88.5	Confident	175 Å²	175	76.7 Å²	76.7	66%	0.66	39%	0.392	S	S	*	.	H	α-helix	trans	-71.1	-31.3	177.6	-70.2	-174.8	-175.6	-137.9	5.1	112.5	E2 I4 F118	E2-R6 WeakPolarHBondContact O-CG 3.4Å; E2-R6 PolarHBondContact O-N 3.21Å; E2-R6 IonicContact OE2-NE 2.69Å; E2-R6 IonicContact OE2-NH2 2.8Å; E2-R6 PolarHBondContact OE2-NH2 3.32Å; I4-R6 PolarHBondContact O-N 3.42Å; R6-F118 HydrophobicContact CG-CE1 4.38Å; R6-F118 HydrophobicContact CG-CE2 3.83Å; R6-F118 HydrophobicContact CG-CZ 3.59Å
7	N	90.3	Very high	89.1	Confident	59 Å²	59	77.6 Å²	77.6	32%	0.316	40%	0.398	S	S	.	.			trans	-94.4	102.9	177.7	-173.6	-43.8	0	0	0	110.6	V3 I4 S9 R10 L11	V3-N7 PolarHBondContact O-N 2.85Å; I4-N7 PolarHBondContact O-N 3.39Å; N7-S9 VanDerWaalsContact C-N 3.26Å; N7-S9 PolarHBondContact O-N 3.01Å; N7-S9 PolarHBondContact OD1-N 2.99Å; N7-S9 VanDerWaalsContact OD1-N 3.09Å; N7-R10 HydrophobicContact CB-CB 4.04Å; N7-R10 HydrophobicContact CB-CG 4.06Å; N7-R10 PolarHBondContact O-N 2.83Å; N7-R10 VanDerWaalsContact O-N 3.11Å; N7-R10 PolarHBondContact OD1-N 2.97Å; N7-R10 VanDerWaalsContact OD1-N 3.1Å; N7-L11 PolarHBondContact O-N 3.41Å
8	S	90.6	Very high	89.6	Confident	56 Å²	56	77.7 Å²	77.7	39%	0.392	39%	0.394	S	S	.	.	H	α-helix	trans	-51.8	-41.1	-178.7	-77.2	0	0	0	0	113.8	F12 F106	S8-F12 WeakPolarHBondContact O-CB 3.42Å; S8-F12 PolarHBondContact O-N 3.08Å; S8-F106 WeakPolarHBondContact O-CE2 3.26Å
9	S	92.5	Very high	90	Very high	86 Å²	86	73.6 Å²	73.6	60%	0.601	37%	0.374	S	S	*	.	H	α-helix	trans	-69.5	-43.4	-179.8	-52.8	0	0	0	0	111.6	N7 F12 V13	N7-S9 VanDerWaalsContact C-N 3.26Å; N7-S9 PolarHBondContact O-N 3.01Å; N7-S9 PolarHBondContact OD1-N 2.99Å; N7-S9 VanDerWaalsContact OD1-N 3.09Å; S9-F12 PolarHBondContact O-N 3.45Å; S9-V13 WeakPolarHBondContact O-CG2 3.42Å; S9-V13 PolarHBondContact O-N 3.11Å
10	R	94.3	Very high	90.4	Very high	140 Å²	140	74 Å²	74	53%	0.528	37%	0.373	S	S	.	.	H	α-helix	trans	-63.8	-43.7	176.6	-67.9	-178.5	-178.2	172.6	-1	111.3	N7 F12 V13 C14	N7-R10 HydrophobicContact CB-CB 4.04Å; N7-R10 HydrophobicContact CB-CG 4.06Å; N7-R10 PolarHBondContact O-N 2.83Å; N7-R10 VanDerWaalsContact O-N 3.11Å; N7-R10 PolarHBondContact OD1-N 2.97Å; N7-R10 VanDerWaalsContact OD1-N 3.1Å; R10-F12 VanDerWaalsContact C-N 3.34Å; R10-F12 PolarHBondContact O-N 3.07Å; R10-V13 PolarHBondContact O-N 2.89Å; R10-C14 PolarHBondContact O-N 2.91Å; R10-C14 PolarHBondContact O-SG 3.12Å; R10-C14 VanDerWaalsContact O-SG 3.33Å
11	L	96.1	Very high	90.8	Very high	6 Å²	6	76.1 Å²	76.1	3%	0.031	38%	0.38	C	S	.	.	H	α-helix	trans	-58.2	-47.2	175.9	-179.5	60.9	0	0	0	111.4	I4 F5 N7 V13 C14 L15 F106 Y109 L125	I4-L11 HydrophobicContact CG2-CB 4.49Å; I4-L11 HydrophobicContact CG2-CD1 4.26Å; F5-L11 HydrophobicContact CD1-CD1 4.01Å; F5-L11 HydrophobicContact CD1-CD2 4.3Å; F5-L11 HydrophobicContact CE1-CD1 4.22Å; N7-L11 PolarHBondContact O-N 3.41Å; L11-V13 PolarHBondContact O-N 3.18Å; L11-C14 PolarHBondContact O-N 3.02Å; L11-L15 HydrophobicContact CD1-CD1 4.32Å; L11-L15 HydrophobicContact CD1-CG 4.36Å; L11-L15 HydrophobicContact CG-CD1 4.08Å; L11-L15 WeakPolarHBondContact O-CG 3.47Å; L11-L15 PolarHBondContact O-N 3.4Å; L11-F106 HydrophobicContact CD2-CD2 4.21Å; L11-F106 HydrophobicContact CD2-CE2 4.4Å; L11-F106 HydrophobicContact CG-CD2 4.43Å; L11-Y109 HydrophobicContact CD2-CD1 3.39Å; L11-Y109 HydrophobicContact CD2-CD2 4.16Å; L11-Y109 HydrophobicContact CD2-CE1 3.57Å; L11-Y109 HydrophobicContact CD2-CE2 4.33Å; L11-Y109 HydrophobicContact CD2-CG 3.69Å; L11-L125 HydrophobicContact CD1-CD2 3.89Å; L11-L125 HydrophobicContact CD2-CD2 4.32Å
12	F	97.1	Very high	92.5	Very high	57 Å²	57	68.4 Å²	68.4	25%	0.25	34%	0.342	C	S	.	.	H	α-helix	trans	-62.2	-42.7	179.7	-177.5	-114	0	0	0	112.4	S8 S9 R10 C14 L15 L16 I103 F106	S8-F12 WeakPolarHBondContact O-CB 3.42Å; S8-F12 PolarHBondContact O-N 3.08Å; S9-F12 PolarHBondContact O-N 3.45Å; R10-F12 VanDerWaalsContact C-N 3.34Å; R10-F12 PolarHBondContact O-N 3.07Å; F12-C14 PolarHBondContact O-N 2.71Å; F12-L15 PolarHBondContact O-N 3.41Å; F12-L16 WeakPolarHBondContact O-CB 3.3Å; F12-L16 PolarHBondContact O-N 3.34Å; F12-I103 HydrophobicContact CE2-CG1 3.92Å; F12-I103 HydrophobicContact CZ-CG1 4.04Å; F12-F106 HydrophobicContact CB-CD2 4.32Å; F12-F106 HydrophobicContact CB-CE2 4.38Å; F12-F106 HydrophobicContact CB-CG 4.42Å; F12-F106 HydrophobicContact CB-CZ 4.48Å; F12-F106 HydrophobicContact CD2-CB 3.92Å; F12-F106 AromaticContact CD2-CD1 3.99Å; F12-F106 HydrophobicContact CD2-CD1 3.99Å; F12-F106 AromaticContact CD2-CG 3.97Å; F12-F106 HydrophobicContact CD2-CG 3.97Å
13	V	97.2	Very high	93.6	Very high	79 Å²	79	64.5 Å²	64.5	48%	0.479	32%	0.324	S	S	.	.	H	α-helix	trans	-61.6	-43.1	175.5	173.1	0	0	0	0	111.4	S9 R10 L11 L15 L16 L17	S9-V13 WeakPolarHBondContact O-CG2 3.42Å; S9-V13 PolarHBondContact O-N 3.11Å; R10-V13 PolarHBondContact O-N 2.89Å; L11-V13 PolarHBondContact O-N 3.18Å; V13-L15 PolarHBondContact O-N 3.3Å; V13-L16 PolarHBondContact O-N 2.93Å; V13-L17 HydrophobicContact CG1-CD1 4.16Å; V13-L17 HydrophobicContact CG1-CG 4.5Å; V13-L17 WeakPolarHBondContact O-CG 3.33Å; V13-L17 PolarHBondContact O-N 3.21Å
14	C	97.4	Very high	94.4	Very high	58 Å²	58	62.2 Å²	62.2	39%	0.392	31%	0.308	S	S	.	.	H	α-helix	trans	-61.3	-43.4	175.9	-69.2	0	0	0	0	112.3	I4 R10 L11 F12 F18	I4-C14 HydrophobicContact CG2-CB 4.46Å; R10-C14 PolarHBondContact O-N 2.91Å; R10-C14 PolarHBondContact O-SG 3.12Å; R10-C14 VanDerWaalsContact O-SG 3.33Å; L11-C14 PolarHBondContact O-N 3.02Å; F12-C14 PolarHBondContact O-N 2.71Å; C14-F18 WeakPolarHBondContact O-CB 3.16Å; C14-F18 PolarHBondContact O-N 3.02Å
15	L	98	Very high	95.1	Very high	10 Å²	10	65.6 Å²	65.6	5%	0.052	33%	0.326	C	S	.	.	H	α-helix	trans	-65.3	-39.8	177.1	-70	171.3	0	0	0	112	L11 F12 V13 F18 R19 A102 D105 F106 L125 V129	L11-L15 HydrophobicContact CD1-CD1 4.32Å; L11-L15 HydrophobicContact CD1-CG 4.36Å; L11-L15 HydrophobicContact CG-CD1 4.08Å; L11-L15 WeakPolarHBondContact O-CG 3.47Å; L11-L15 PolarHBondContact O-N 3.4Å; F12-L15 PolarHBondContact O-N 3.41Å; V13-L15 PolarHBondContact O-N 3.3Å; L15-F18 PolarHBondContact O-N 3.21Å; L15-R19 WeakPolarHBondContact O-CG 3.48Å; L15-R19 PolarHBondContact O-N 3.2Å; L15-A102 HydrophobicContact CB-CB 4.36Å; L15-D105 HydrophobicContact CD1-CB 3.94Å; L15-D105 HydrophobicContact CD2-CB 4Å; L15-D105 HydrophobicContact CG-CB 4.45Å; L15-F106 HydrophobicContact CD1-CB 3.89Å; L15-L125 HydrophobicContact CD1-CD2 4.31Å; L15-L125 HydrophobicContact CD2-CD1 4.23Å; L15-L125 HydrophobicContact CD2-CD2 4.19Å; L15-V129 HydrophobicContact CD2-CG1 4.07Å
16	L	98.1	Very high	95.5	Very high	58 Å²	58	64.8 Å²	64.8	30%	0.304	32%	0.323	S	S	.	.	H	α-helix	trans	-62.5	-48.7	177	-178.3	63.8	0	0	0	111.3	F12 V13 F18 R19 F20 F99 A102	F12-L16 WeakPolarHBondContact O-CB 3.3Å; F12-L16 PolarHBondContact O-N 3.34Å; V13-L16 PolarHBondContact O-N 2.93Å; L16-F18 PolarHBondContact O-N 2.88Å; L16-R19 PolarHBondContact O-N 2.72Å; L16-F20 VanDerWaalsContact O-CB 3.24Å; L16-F20 WeakPolarHBondContact O-CB 3.11Å; L16-F20 PolarHBondContact O-N 2.89Å; L16-F99 HydrophobicContact CD1-CD2 3.63Å; L16-F99 HydrophobicContact CD1-CE2 4.34Å; L16-A102 HydrophobicContact CB-CB 4.35Å; L16-A102 HydrophobicContact CD1-CB 4.24Å
17	L	98.2	Very high	95.8	Very high	93 Å²	93	65.1 Å²	65.1	49%	0.487	33%	0.332	S	S	.	.	H	α-helix	trans	-60.6	-46.1	175.6	-69.5	173.9	0	0	0	111.1	V13 R19 F20 F21	V13-L17 HydrophobicContact CG1-CD1 4.16Å; V13-L17 HydrophobicContact CG1-CG 4.5Å; V13-L17 WeakPolarHBondContact O-CG 3.33Å; V13-L17 PolarHBondContact O-N 3.21Å; L17-R19 PolarHBondContact O-N 3.16Å; L17-F20 PolarHBondContact O-N 3.21Å; L17-F21 HydrophobicContact CB-CE2 4.48Å; L17-F21 WeakPolarHBondContact O-CD2 3.25Å; L17-F21 PolarHBondContact O-N 3.01Å
18	F	98.1	Very high	95.9	Very high	78 Å²	78	66.1 Å²	66.1	34%	0.342	34%	0.341	S	S	.	.	H	α-helix	trans	-56.9	-49.3	177.7	171.5	-105.8	0	0	0	112.1	C14 L15 L16 F21 N22 V129 I135	C14-F18 WeakPolarHBondContact O-CB 3.16Å; C14-F18 PolarHBondContact O-N 3.02Å; L15-F18 PolarHBondContact O-N 3.21Å; L16-F18 PolarHBondContact O-N 2.88Å; F18-F21 PolarHBondContact O-N 3.1Å; F18-N22 WeakPolarHBondContact O-CB 3.28Å; F18-N22 PolarHBondContact O-N 3.31Å; F18-V129 HydrophobicContact CE1-CB 3.85Å; F18-V129 HydrophobicContact CE1-CG1 4.3Å; F18-V129 HydrophobicContact CZ-CB 4.22Å; F18-I135 HydrophobicContact CZ-CG1 4.38Å
19	R	98.1	Very high	95.9	Very high	0 Å²	0	67 Å²	67	0%	0	35%	0.347	C	S	.	.	H	α-helix	trans	-72.4	-29.8	-179.7	-68	-63.6	-173.5	179.7	-0.7	113.5	L15 L16 L17 N22 A23 G98 A101 A102 D105 T134	L15-R19 WeakPolarHBondContact O-CG 3.48Å; L15-R19 PolarHBondContact O-N 3.2Å; L16-R19 PolarHBondContact O-N 2.72Å; L17-R19 PolarHBondContact O-N 3.16Å; R19-N22 PolarHBondContact NH1-ND2 3.02Å; R19-N22 PolarHBondContact O-N 3.15Å; R19-A23 WeakPolarHBondContact O-CB 3.3Å; R19-A23 PolarHBondContact O-N 3.4Å; R19-G98 WeakPolarHBondContact CB-O 3.37Å; R19-A101 HydrophobicContact CG-CB 4.14Å; R19-A102 HydrophobicContact CB-CB 4.09Å; R19-A102 HydrophobicContact CG-CB 3.96Å; R19-D105 IonicContact CZ-OD1 3.43Å; R19-D105 IonicContact CZ-OD2 3.31Å; R19-D105 VanDerWaalsContact CZ-OD2 3.24Å; R19-D105 IonicContact NE-OD1 3.25Å; R19-D105 IonicContact NE-OD2 3.68Å; R19-D105 PolarHBondContact NE-OD2 3.01Å; R19-D105 VanDerWaalsContact NH2-CG 3.27Å; R19-D105 IonicContact NH2-OD1 2.62Å; R19-D105 PolarHBondContact NH2-OD1 3.41Å; R19-D105 IonicContact NH2-OD2 2.68Å; R19-D105 PolarHBondContact NH2-OD2 3.39Å; R19-T134 PolarHBondContact NH1-O 3.12Å
20	F	98.1	Very high	95.8	Very high	82 Å²	82	65.2 Å²	65.2	36%	0.36	33%	0.327	S	S	.	.	H	α-helix	trans	-61.7	-52.1	170.6	177.9	-101	0	0	0	110.9	L16 L17 N22 A23 L24 I95	L16-F20 VanDerWaalsContact O-CB 3.24Å; L16-F20 WeakPolarHBondContact O-CB 3.11Å; L16-F20 PolarHBondContact O-N 2.89Å; L17-F20 PolarHBondContact O-N 3.21Å; F20-N22 VanDerWaalsContact C-N 3.32Å; F20-N22 PolarHBondContact O-N 2.92Å; F20-A23 WeakPolarHBondContact O-CB 3.23Å; F20-A23 PolarHBondContact O-N 3.22Å; F20-L24 HydrophobicContact CD1-CD1 4.08Å; F20-L24 HydrophobicContact CE1-CD1 3.51Å; F20-L24 HydrophobicContact CE1-CG 4.34Å; F20-L24 HydrophobicContact CZ-CD1 3.82Å; F20-L24 HydrophobicContact CZ-CG 4.4Å; F20-L24 WeakPolarHBondContact O-CG 3.45Å; F20-L24 PolarHBondContact O-N 2.8Å; F20-L24 VanDerWaalsContact O-N 3.12Å; F20-I95 HydrophobicContact CD2-CG1 4.44Å; F20-I95 HydrophobicContact CD2-CG2 4.01Å; F20-I95 HydrophobicContact CE2-CD1 4.18Å; F20-I95 HydrophobicContact CE2-CG1 4.22Å; F20-I95 HydrophobicContact CE2-CG2 4.07Å
21	F	97.8	Very high	95.8	Very high	118 Å²	118	59.3 Å²	59.3	52%	0.518	31%	0.307	S	S	.	.	H	α-helix	trans	-62.7	-39.1	175.8	-73.2	-65	0	0	0	112.2	L17 F18 A23 L24 L25	L17-F21 HydrophobicContact CB-CE2 4.48Å; L17-F21 WeakPolarHBondContact O-CD2 3.25Å; L17-F21 PolarHBondContact O-N 3.01Å; F18-F21 PolarHBondContact O-N 3.1Å; F21-A23 PolarHBondContact O-N 2.87Å; F21-L24 PolarHBondContact O-N 2.96Å; F21-L24 VanDerWaalsContact O-N 3.15Å; F21-L25 VanDerWaalsContact O-CG 3.28Å; F21-L25 WeakPolarHBondContact O-CG 3.19Å; F21-L25 PolarHBondContact O-N 2.99Å
22	N	97.4	Very high	95.7	Very high	12 Å²	12	63 Å²	63	6%	0.064	33%	0.331	C	S	.	.	H	α-helix	trans	-57.3	-47.1	174.3	-173.3	6.4	0	0	0	111.6	F18 R19 F20 L24 L25 I26 I135 P139	F18-N22 WeakPolarHBondContact O-CB 3.28Å; F18-N22 PolarHBondContact O-N 3.31Å; R19-N22 PolarHBondContact NH1-ND2 3.02Å; R19-N22 PolarHBondContact O-N 3.15Å; F20-N22 VanDerWaalsContact C-N 3.32Å; F20-N22 PolarHBondContact O-N 2.92Å; N22-L24 VanDerWaalsContact C-N 3.29Å; N22-L24 PolarHBondContact O-N 3.45Å; N22-L25 PolarHBondContact O-N 3.42Å; N22-I26 PolarHBondContact O-N 2.9Å; N22-I135 PolarHBondContact ND2-O 3.22Å; N22-I135 PolarHBondContact OD1-O 3.18Å; N22-P139 HydrophobicContact CB-CG 4.12Å; N22-P139 VanDerWaalsContact CG-CG 3.46Å; N22-P139 WeakPolarHBondContact ND2-CG 3.39Å
23	A	97	Very high	95.4	Very high	0 Å²	0	61.9 Å²	61.9	0%	0	33%	0.328	C	S	.	.	H	α-helix	trans	-59.3	-38	175.6	0	0	0	0	0	113.1	R19 F20 F21 K91 Q94 I95 P139	R19-A23 WeakPolarHBondContact O-CB 3.3Å; R19-A23 PolarHBondContact O-N 3.4Å; F20-A23 WeakPolarHBondContact O-CB 3.23Å; F20-A23 PolarHBondContact O-N 3.22Å; F21-A23 PolarHBondContact O-N 2.87Å; A23-K91 PolarHBondContact O-NZ 2.9Å; A23-Q94 HydrophobicContact CB-CB 4.15Å; A23-Q94 WeakPolarHBondContact CB-O 3.33Å; A23-Q94 PolarHBondContact O-OE1 3.3Å; A23-I95 HydrophobicContact CB-CG1 4.39Å; A23-P139 HydrophobicContact CB-CB 3.8Å
24	L	96.1	Very high	95.3	Very high	46 Å²	46	58.1 Å²	58.1	24%	0.241	31%	0.305	C	S	.	.	H	α-helix	trans	-68.6	-37	177.3	-64.6	-177.6	0	0	0	112.5	F20 F21 N22 W87 K91 I95	F20-L24 HydrophobicContact CD1-CD1 4.08Å; F20-L24 HydrophobicContact CE1-CD1 3.51Å; F20-L24 HydrophobicContact CE1-CG 4.34Å; F20-L24 HydrophobicContact CZ-CD1 3.82Å; F20-L24 HydrophobicContact CZ-CG 4.4Å; F20-L24 WeakPolarHBondContact O-CG 3.45Å; F20-L24 PolarHBondContact O-N 2.8Å; F20-L24 VanDerWaalsContact O-N 3.12Å; F21-L24 PolarHBondContact O-N 2.96Å; F21-L24 VanDerWaalsContact O-N 3.15Å; N22-L24 VanDerWaalsContact C-N 3.29Å; N22-L24 PolarHBondContact O-N 3.45Å; L24-W87 HydrophobicContact CD2-CH2 4.02Å; L24-W87 HydrophobicContact CD2-CZ2 4.07Å; L24-K91 PolarHBondContact O-NZ 3.38Å; L24-K91 VanDerWaalsContact O-NZ 3.09Å; L24-I95 HydrophobicContact CD2-CD1 4.1Å; L24-I95 HydrophobicContact CD2-CG1 4.3Å
25	L	95.4	Very high	95.1	Very high	134 Å²	134	59.2 Å²	59.2	70%	0.702	30%	0.301	S	S	*	.	H	α-helix	trans	-75.4	-20.5	-176.4	-69.7	172.1	0	0	0	114.3	F21 N22 Q27	F21-L25 VanDerWaalsContact O-CG 3.28Å; F21-L25 WeakPolarHBondContact O-CG 3.19Å; F21-L25 PolarHBondContact O-N 2.99Å; N22-L25 PolarHBondContact O-N 3.42Å; L25-Q27 PolarHBondContact O-N 3.44Å
26	I	92.9	Very high	94.9	Very high	14 Å²	14	64.3 Å²	64.3	7%	0.072	32%	0.32	C	S	.	.			trans	-67.6	117.7	178.2	-68.4	174.8	0	0	0	110.4	N22 K91 P139 R140	N22-I26 PolarHBondContact O-N 2.9Å; I26-K91 PolarHBondContact O-NZ 3.43Å; I26-P139 HydrophobicContact CD1-CB 3.86Å; I26-P139 HydrophobicContact CD1-CG 3.51Å; I26-R140 HydrophobicContact CD1-CG 4.29Å
27	Q	91.2	Very high	94.8	Very high	182 Å²	182	62 Å²	62	85%	0.85	31%	0.308	S	S	*	.			trans	-122	-0.7	176.7	-64.7	-179.4	1	0	0	113.2	L25	L25-Q27 PolarHBondContact O-N 3.44Å
28	T	92.5	Very high	94.6	Very high	80 Å²	80	57.6 Å²	57.6	49%	0.491	29%	0.285	S	S	.	.			trans	-99.2	154.5	-174.9	52	0	0	0	0	111.7	R140	T28-R140 VanDerWaalsContact O-CZ 3.29Å; T28-R140 PolarHBondContact O-NH1 2.98Å; T28-R140 PolarHBondContact O-NH2 2.88Å; T28-R140 PolarHBondContact OG1-NH2 2.88Å
29	S	89.5	Confident	94.4	Very high	75 Å²	75	55 Å²	55	52%	0.524	27%	0.274	S	S	.	.			trans	-85.6	153	166.5	-165.1	0	0	0	0	110.7	Y35 Y136	S29-Y35 WeakPolarHBondContact OG-CE2 3.28Å; S29-Y35 PolarHBondContact OG-OH 3.43Å; S29-Y136 PolarHBondContact O-OH 3.41Å
30	Y	92.1	Very high	94.3	Very high	47 Å²	47	57.4 Å²	57.4	18%	0.184	29%	0.285	C	S	.	.			trans	-116.2	-62	173.4	-179.1	-154.8	0	0	0	111.3	Y136 L142 R381	Y30-Y136 WeakPolarHBondContact CA-OH 3.37Å; Y30-Y136 VanDerWaalsContact CB-OH 3.24Å; Y30-Y136 WeakPolarHBondContact CB-OH 3.4Å; Y30-Y136 HydrophobicContact CD1-CE1 4.15Å; Y30-Y136 AromaticContact CD2-CE1 3.8Å; Y30-Y136 HydrophobicContact CD2-CE1 3.8Å; Y30-Y136 VanDerWaalsContact CD2-OH 3.3Å; Y30-Y136 WeakPolarHBondContact CD2-OH 3.14Å; Y30-Y136 HydrophobicContact CE1-CE1 4.47Å; Y30-Y136 HydrophobicContact CE2-CE1 4.16Å; Y30-Y136 AromaticContact CG-CE1 3.82Å; Y30-Y136 HydrophobicContact CG-CE1 3.82Å; Y30-L142 HydrophobicContact CD1-CD1 3.7Å; Y30-L142 HydrophobicContact CE1-CD1 4.08Å; Y30-R381 HydrophobicContact CE1-CB 4.1Å
31	V	93.4	Very high	94.3	Very high	16 Å²	16	53.5 Å²	53.5	10%	0.097	27%	0.268	C	S	.	.			trans	-146.2	148.7	-172.9	-74.4	0	0	0	0	110.5	D33 E34 L142	V31-D33 HydrophobicContact CG2-CB 4.35Å; V31-D33 PolarHBondContact O-N 2.86Å; V31-D33 VanDerWaalsContact O-N 3.15Å; V31-E34 HydrophobicContact CG2-CB 4.48Å; V31-E34 VanDerWaalsContact O-CB 3.28Å; V31-E34 WeakPolarHBondContact O-CB 3.39Å; V31-E34 PolarHBondContact O-N 3.36Å; V31-L142 HydrophobicContact CG2-CD1 3.96Å; V31-L142 HydrophobicContact CG2-CD2 3.71Å; V31-L142 HydrophobicContact CG2-CG 4.43Å
32	P	93.2	Very high	94.2	Very high	84 Å²	84	47.9 Å²	47.9	55%	0.545	24%	0.244	S	C	.	.	T	Hydrogen-bonded Turn	trans	-56	-33.4	179.7	-26.1	35.1	0	0	0	113.3	E34 Y35 W36	P32-E34 PolarHBondContact O-N 2.91Å; P32-E34 VanDerWaalsContact O-N 3.1Å; P32-Y35 PolarHBondContact O-N 3.28Å; P32-W36 PolarHBondContact O-N 2.72Å
33	D	92.7	Very high	94.2	Very high	33 Å²	33	48.3 Å²	48.3	18%	0.176	25%	0.245	C	C	.	.	H	α-helix	trans	-56	-25.9	177.4	-68.1	13.9	0	0	0	113.3	V31 Y35 Q37 L142 R381	V31-D33 HydrophobicContact CG2-CB 4.35Å; V31-D33 PolarHBondContact O-N 2.86Å; V31-D33 VanDerWaalsContact O-N 3.15Å; D33-Y35 PolarHBondContact O-N 2.9Å; D33-Q37 HydrophobicContact CB-CG 4.37Å; D33-Q37 VanDerWaalsContact CG-CD 3.41Å; D33-Q37 WeakPolarHBondContact O-CB 3.3Å; D33-Q37 PolarHBondContact O-N 3.18Å; D33-Q37 PolarHBondContact OD1-NE2 3.17Å; D33-Q37 VanDerWaalsContact OD1-NE2 3.17Å; D33-Q37 PolarHBondContact OD2-NE2 3.09Å; D33-Q37 PolarHBondContact OD2-OE1 3.35Å; D33-L142 HydrophobicContact CB-CD2 4.08Å; D33-R381 IonicContact OD2-CZ 3.47Å; D33-R381 VanDerWaalsContact OD2-CZ 3.31Å; D33-R381 IonicContact OD2-NH1 3.95Å; D33-R381 IonicContact OD2-NH2 3.4Å; D33-R381 PolarHBondContact OD2-NH2 3.46Å
34	E	93.9	Very high	94.2	Very high	0 Å²	0	51.5 Å²	51.5	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-63.6	-26	177.2	-173.8	172.2	-174.9	0	0	112.8	V31 P32 S38 I39 R140 S141 L142	V31-E34 HydrophobicContact CG2-CB 4.48Å; V31-E34 VanDerWaalsContact O-CB 3.28Å; V31-E34 WeakPolarHBondContact O-CB 3.39Å; V31-E34 PolarHBondContact O-N 3.36Å; P32-E34 PolarHBondContact O-N 2.91Å; P32-E34 VanDerWaalsContact O-N 3.1Å; E34-S38 PolarHBondContact O-OG 3.4Å; E34-I39 WeakPolarHBondContact O-CD1 3.45Å; E34-I39 WeakPolarHBondContact O-CG1 3.1Å; E34-R140 WeakPolarHBondContact OE1-CB 3.33Å; E34-R140 WeakPolarHBondContact OE1-CG 3.47Å; E34-R140 IonicContact OE1-NH1 3.89Å; E34-R140 PolarHBondContact OE1-NH1 3.41Å; E34-R140 IonicContact OE2-CZ 2.72Å; E34-R140 IonicContact OE2-NH1 3.16Å; E34-R140 PolarHBondContact OE2-NH1 3.4Å; E34-S141 WeakPolarHBondContact CG-OG 3.31Å; E34-S141 PolarHBondContact O-OG 3.27Å; E34-L142 HydrophobicContact CB-CD2 3.85Å; E34-L142 HydrophobicContact CB-CG 4.12Å; E34-L142 HydrophobicContact CG-CG 4.34Å
35	Y	93.5	Very high	94.2	Very high	82 Å²	82	52.7 Å²	52.7	32%	0.322	26%	0.26	S	S	.	.	I	π-helix	trans	-108	-52.7	-178.7	-49.4	-82	0	0	0	110.9	S29 P32 D33 Q37 S38 I39 E40	S29-Y35 WeakPolarHBondContact OG-CE2 3.28Å; S29-Y35 PolarHBondContact OG-OH 3.43Å; P32-Y35 PolarHBondContact O-N 3.28Å; D33-Y35 PolarHBondContact O-N 2.9Å; Y35-Q37 PolarHBondContact O-N 3.34Å; Y35-S38 PolarHBondContact O-N 3.39Å; Y35-I39 HydrophobicContact CD1-CD1 3.88Å; Y35-I39 HydrophobicContact CE1-CD1 4.29Å; Y35-I39 PolarHBondContact O-N 3.11Å; Y35-E40 WeakPolarHBondContact O-CB 3.47Å; Y35-E40 PolarHBondContact O-N 3.46Å
36	W	94.7	Very high	94.3	Very high	116 Å²	116	47.7 Å²	47.7	44%	0.439	24%	0.235	S	C	.	.	I	π-helix	trans	-79.7	-13.6	-168.1	-59.2	113.2	0	0	0	114.7	P32 E40 V41 A51 T53 W56	P32-W36 PolarHBondContact O-N 2.72Å; W36-E40 HydrophobicContact CE3-CB 4.26Å; W36-E40 HydrophobicContact CE3-CG 4.02Å; W36-E40 HydrophobicContact CZ3-CG 3.95Å; W36-V41 WeakPolarHBondContact O-CG2 3.32Å; W36-A51 HydrophobicContact CZ3-CB 4.16Å; W36-T53 HydrophobicContact CB-CG2 3.75Å; W36-T53 HydrophobicContact CD2-CG2 4.34Å; W36-T53 HydrophobicContact CE3-CG2 4.23Å; W36-T53 HydrophobicContact CG-CG2 4.18Å; W36-W56 PolarHBondContact O-NE1 3.16Å
37	Q	94.6	Very high	94.5	Very high	10 Å²	10	49.4 Å²	49.4	5%	0.047	24%	0.242	C	C	.	.	I	π-helix	trans	-107	-1.9	175.1	-67.1	173.3	7.2	0	0	113.3	D33 Y35 E55 W56 R63 P68	D33-Q37 HydrophobicContact CB-CG 4.37Å; D33-Q37 VanDerWaalsContact CG-CD 3.41Å; D33-Q37 WeakPolarHBondContact O-CB 3.3Å; D33-Q37 PolarHBondContact O-N 3.18Å; D33-Q37 PolarHBondContact OD1-NE2 3.17Å; D33-Q37 VanDerWaalsContact OD1-NE2 3.17Å; D33-Q37 PolarHBondContact OD2-NE2 3.09Å; D33-Q37 PolarHBondContact OD2-OE1 3.35Å; Y35-Q37 PolarHBondContact O-N 3.34Å; Q37-E55 WeakPolarHBondContact CG-OE2 3.15Å; Q37-E55 PolarHBondContact NE2-OE1 3.15Å; Q37-E55 PolarHBondContact NE2-OE2 3.01Å; Q37-W56 WeakPolarHBondContact O-CZ2 3.44Å; Q37-R63 VanDerWaalsContact CD-CZ 3.49Å; Q37-R63 HydrophobicContact CG-CG 4.48Å; Q37-P68 WeakPolarHBondContact O-CG 3.38Å
38	S	94	Very high	94.7	Very high	1 Å²	1	43.9 Å²	43.9	1%	0.007	24%	0.235	C	C	.	.	I	π-helix	trans	-146.6	-72	-172.8	62.7	0	0	0	0	113	E34 Y35 A42 H67 S141	E34-S38 PolarHBondContact O-OG 3.4Å; Y35-S38 PolarHBondContact O-N 3.39Å; S38-A42 VanDerWaalsContact O-CB 3.23Å; S38-A42 WeakPolarHBondContact O-CB 3.2Å; S38-A42 PolarHBondContact O-N 3.43Å; S38-H67 VanDerWaalsContact CB-CE1 3.48Å; S38-H67 WeakPolarHBondContact CB-CE1 3.24Å; S38-S141 WeakPolarHBondContact CB-O 3.44Å; S38-S141 PolarHBondContact OG-O 3.36Å
39	I	95.3	Very high	94.8	Very high	24 Å²	24	47.3 Å²	47.3	12%	0.123	24%	0.24	C	C	.	.	I	π-helix	trans	-60.1	-55.1	-173.9	-64.6	177	0	0	0	111.3	E34 Y35 V41 A42 H43 Y75 P93 S141	E34-I39 WeakPolarHBondContact O-CD1 3.45Å; E34-I39 WeakPolarHBondContact O-CG1 3.1Å; Y35-I39 HydrophobicContact CD1-CD1 3.88Å; Y35-I39 HydrophobicContact CE1-CD1 4.29Å; Y35-I39 PolarHBondContact O-N 3.11Å; I39-V41 VanDerWaalsContact C-N 3.3Å; I39-V41 PolarHBondContact O-N 3.26Å; I39-A42 PolarHBondContact O-N 2.68Å; I39-H43 VanDerWaalsContact O-CB 3.29Å; I39-H43 WeakPolarHBondContact O-CB 3.34Å; I39-H43 PolarHBondContact O-N 3.49Å; I39-Y75 WeakPolarHBondContact CG2-OH 3.31Å; I39-P93 HydrophobicContact CD1-CG 4.47Å; I39-P93 HydrophobicContact CG1-CB 4.25Å; I39-P93 HydrophobicContact CG1-CG 4.16Å; I39-S141 WeakPolarHBondContact CD1-OG 3.47Å; I39-S141 WeakPolarHBondContact CG1-OG 3.38Å
40	E	96.1	Very high	94.9	Very high	49 Å²	49	45.3 Å²	45.3	23%	0.229	23%	0.23	C	C	.	.	H	α-helix	trans	-66.1	-37.5	-174	-176.4	65.4	-167.4	0	0	111.4	Y35 W36 H43 K44 G50 A51	Y35-E40 WeakPolarHBondContact O-CB 3.47Å; Y35-E40 PolarHBondContact O-N 3.46Å; W36-E40 HydrophobicContact CE3-CB 4.26Å; W36-E40 HydrophobicContact CE3-CG 4.02Å; W36-E40 HydrophobicContact CZ3-CG 3.95Å; E40-H43 PolarHBondContact O-N 3.37Å; E40-K44 WeakPolarHBondContact O-CB 3.23Å; E40-K44 PolarHBondContact O-N 3.3Å; E40-G50 WeakPolarHBondContact OE1-CA 3.46Å; E40-A51 WeakPolarHBondContact CG-O 3.41Å; E40-A51 PolarHBondContact OE1-N 2.84Å
41	V	96.7	Very high	94.9	Very high	0 Å²	0	45.4 Å²	45.4	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-62.7	-49.6	176.8	-177.2	0	0	0	0	110	W36 I39 H43 K44 W45 L52 W56 P68	W36-V41 WeakPolarHBondContact O-CG2 3.32Å; I39-V41 VanDerWaalsContact C-N 3.3Å; I39-V41 PolarHBondContact O-N 3.26Å; V41-H43 VanDerWaalsContact C-N 3.33Å; V41-H43 PolarHBondContact O-N 2.76Å; V41-K44 PolarHBondContact O-N 2.96Å; V41-W45 HydrophobicContact CG1-CD2 4.12Å; V41-W45 HydrophobicContact CG1-CE3 4.44Å; V41-W45 HydrophobicContact CG1-CH2 3.77Å; V41-W45 HydrophobicContact CG1-CZ2 3.38Å; V41-W45 HydrophobicContact CG1-CZ3 4.27Å; V41-W45 PolarHBondContact O-N 2.78Å; V41-W45 VanDerWaalsContact O-N 3.09Å; V41-L52 HydrophobicContact CB-CD2 4.19Å; V41-L52 HydrophobicContact CG1-CD2 4.06Å; V41-L52 HydrophobicContact CG2-CD2 4.02Å; V41-W56 HydrophobicContact CB-CZ2 4.33Å; V41-W56 HydrophobicContact CG1-CD2 3.99Å; V41-W56 HydrophobicContact CG1-CE3 4.07Å; V41-W56 HydrophobicContact CG1-CH2 4.1Å; V41-W56 HydrophobicContact CG1-CZ2 3.97Å; V41-W56 HydrophobicContact CG1-CZ3 4.13Å; V41-W56 HydrophobicContact CG2-CD2 4.04Å; V41-W56 HydrophobicContact CG2-CG 4.31Å; V41-W56 HydrophobicContact CG2-CZ2 3.76Å; V41-P68 HydrophobicContact CB-CB 4.15Å; V41-P68 HydrophobicContact CB-CG 4.44Å; V41-P68 HydrophobicContact CG1-CB 3.99Å; V41-P68 HydrophobicContact CG1-CG 4.25Å
42	A	97.1	Very high	94.9	Very high	0 Å²	0	47.9 Å²	47.9	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-63.8	-41.1	178.9	0	0	0	0	0	112.2	S38 I39 W45 V46 P68 I71 S72 Y75	S38-A42 VanDerWaalsContact O-CB 3.23Å; S38-A42 WeakPolarHBondContact O-CB 3.2Å; S38-A42 PolarHBondContact O-N 3.43Å; I39-A42 PolarHBondContact O-N 2.68Å; A42-W45 PolarHBondContact O-N 2.85Å; A42-V46 WeakPolarHBondContact O-CG2 3.28Å; A42-V46 PolarHBondContact O-N 2.62Å; A42-P68 HydrophobicContact CB-CB 4.37Å; A42-P68 WeakPolarHBondContact CB-O 3.48Å; A42-I71 HydrophobicContact CB-CB 3.72Å; A42-I71 HydrophobicContact CB-CG2 3.65Å; A42-S72 WeakPolarHBondContact CA-OG 3.32Å; A42-S72 VanDerWaalsContact CB-OG 3.26Å; A42-S72 WeakPolarHBondContact CB-OG 3.31Å; A42-Y75 HydrophobicContact CB-CD2 4.05Å; A42-Y75 HydrophobicContact CB-CE2 4.05Å
43	H	97.3	Very high	95	Very high	22 Å²	22	45.7 Å²	45.7	10%	0.102	24%	0.239	C	C	.	.	H	α-helix	trans	-59.7	-50.2	176.1	-179.5	-82.4	0	0	0	110.8	I39 E40 V41 W45 V46 F47 Y49 Y75	I39-H43 VanDerWaalsContact O-CB 3.29Å; I39-H43 WeakPolarHBondContact O-CB 3.34Å; I39-H43 PolarHBondContact O-N 3.49Å; E40-H43 PolarHBondContact O-N 3.37Å; V41-H43 VanDerWaalsContact C-N 3.33Å; V41-H43 PolarHBondContact O-N 2.76Å; H43-W45 VanDerWaalsContact C-N 3.33Å; H43-W45 PolarHBondContact O-N 3.37Å; H43-V46 PolarHBondContact O-N 3.35Å; H43-V46 VanDerWaalsContact O-N 3.15Å; H43-F47 AromaticContact CD2-CD2 3.39Å; H43-F47 WeakPolarHBondContact CD2-CD2 3.33Å; H43-F47 AromaticContact CD2-CE2 3.75Å; H43-F47 AromaticContact CE1-CD2 3.89Å; H43-F47 AromaticContact CG-CD2 3.88Å; H43-F47 AromaticContact NE2-CD2 3.41Å; H43-F47 WeakPolarHBondContact NE2-CD2 3.39Å; H43-F47 AromaticContact NE2-CE2 3.98Å; H43-F47 AromaticContact NE2-CG 3.91Å; H43-F47 WeakPolarHBondContact O-CD2 3.22Å; H43-F47 PolarHBondContact O-N 3.25Å; H43-Y49 AromaticContact CE1-CD2 4Å; H43-Y49 AromaticContact CE1-CE1 3.84Å; H43-Y49 AromaticContact CE1-CE2 3.45Å; H43-Y49 VanDerWaalsContact CE1-CE2 3.45Å; H43-Y49 WeakPolarHBondContact CE1-CE2 3.46Å; H43-Y49 AromaticContact CE1-CZ 3.34Å; H43-Y49 PolarHBondContact ND1-O 2.96Å; H43-Y49 AromaticContact NE2-CZ 3.85Å; H43-Y75 HydrophobicContact CB-CD2 4.39Å; H43-Y75 HydrophobicContact CB-CE2 4Å
44	K	96.7	Very high	95	Very high	66 Å²	66	49.1 Å²	49.1	29%	0.287	25%	0.249	S	C	.	.	H	α-helix	trans	-59.4	-41.2	178.2	-173.5	-178.9	-174.5	150.8	0	113.1	E40 V41 V46 G48 Y49 G50 L52	E40-K44 WeakPolarHBondContact O-CB 3.23Å; E40-K44 PolarHBondContact O-N 3.3Å; V41-K44 PolarHBondContact O-N 2.96Å; K44-V46 VanDerWaalsContact C-N 3.26Å; K44-V46 PolarHBondContact O-N 3.4Å; K44-G48 VanDerWaalsContact O-CA 3.3Å; K44-G48 WeakPolarHBondContact O-CA 3.17Å; K44-G48 PolarHBondContact O-N 3.28Å; K44-Y49 VanDerWaalsContact CA-O 3.28Å; K44-Y49 WeakPolarHBondContact CA-O 3.42Å; K44-G50 WeakPolarHBondContact CD-O 3.5Å; K44-G50 WeakPolarHBondContact CE-O 3.45Å; K44-G50 PolarHBondContact NZ-O 3.4Å; K44-L52 HydrophobicContact CD-CD1 3.85Å; K44-L52 HydrophobicContact CD-CD2 3.86Å; K44-L52 HydrophobicContact CD-CG 3.5Å; K44-L52 VanDerWaalsContact CD-CG 3.5Å
45	W	95.7	Very high	94.9	Very high	71 Å²	71	49.8 Å²	49.8	27%	0.269	25%	0.252	S	S	.	.	H	α-helix	trans	-64.7	-29.2	178.9	-68.2	-12.6	0	0	0	113.4	V41 A42 H43 W56 P65 P68 L69 T270	V41-W45 HydrophobicContact CG1-CD2 4.12Å; V41-W45 HydrophobicContact CG1-CE3 4.44Å; V41-W45 HydrophobicContact CG1-CH2 3.77Å; V41-W45 HydrophobicContact CG1-CZ2 3.38Å; V41-W45 HydrophobicContact CG1-CZ3 4.27Å; V41-W45 PolarHBondContact O-N 2.78Å; V41-W45 VanDerWaalsContact O-N 3.09Å; A42-W45 PolarHBondContact O-N 2.85Å; H43-W45 VanDerWaalsContact C-N 3.33Å; H43-W45 PolarHBondContact O-N 3.37Å; W45-W56 HydrophobicContact CH2-CH2 4.49Å; W45-W56 HydrophobicContact CH2-CZ3 4.01Å; W45-W56 HydrophobicContact CZ2-CE3 4.2Å; W45-W56 AromaticContact CZ2-CZ3 3.98Å; W45-W56 HydrophobicContact CZ2-CZ3 3.98Å; W45-P65 HydrophobicContact CH2-CB 3.72Å; W45-P65 HydrophobicContact CZ3-CB 4.41Å; W45-P68 HydrophobicContact CE3-CB 4.43Å; W45-P68 HydrophobicContact CH2-CB 4.03Å; W45-P68 HydrophobicContact CH2-CG 4.43Å; W45-P68 HydrophobicContact CZ3-CB 3.7Å; W45-L69 HydrophobicContact CE3-CD2 3.94Å; W45-L69 HydrophobicContact CE3-CG 4.31Å; W45-L69 HydrophobicContact CZ3-CB 4.47Å; W45-L69 HydrophobicContact CZ3-CD2 3.84Å; W45-L69 HydrophobicContact CZ3-CG 3.69Å; W45-T270 HydrophobicContact CH2-CG2 4.05Å; W45-T270 HydrophobicContact CZ2-CG2 3.46Å; W45-T270 VanDerWaalsContact CZ2-CG2 3.46Å
46	V	97.1	Very high	95	Very high	29 Å²	29	46.3 Å²	46.3	18%	0.176	24%	0.239	C	C	.	.	H	α-helix	trans	-91.2	-45.7	-178.9	174.8	0	0	0	0	112.5	A42 H43 K44 S72 K76 A79	A42-V46 WeakPolarHBondContact O-CG2 3.28Å; A42-V46 PolarHBondContact O-N 2.62Å; H43-V46 PolarHBondContact O-N 3.35Å; H43-V46 VanDerWaalsContact O-N 3.15Å; K44-V46 VanDerWaalsContact C-N 3.26Å; K44-V46 PolarHBondContact O-N 3.4Å; V46-S72 WeakPolarHBondContact CG2-O 3.39Å; V46-K76 HydrophobicContact CG1-CB 4.31Å; V46-K76 HydrophobicContact CG1-CD 4.14Å; V46-K76 HydrophobicContact CG2-CB 4.31Å; V46-A79 HydrophobicContact CG1-CB 4.48Å
47	F	96.8	Very high	94.9	Very high	50 Å²	50	44.8 Å²	44.8	22%	0.219	24%	0.237	C	C	.	.	H	α-helix	trans	-98	-10.4	-171.4	-63.4	-77.8	0	0	0	113.7	H43 Y49 Y75 A79 D84 I89	H43-F47 AromaticContact CD2-CD2 3.39Å; H43-F47 WeakPolarHBondContact CD2-CD2 3.33Å; H43-F47 AromaticContact CD2-CE2 3.75Å; H43-F47 AromaticContact CE1-CD2 3.89Å; H43-F47 AromaticContact CG-CD2 3.88Å; H43-F47 AromaticContact NE2-CD2 3.41Å; H43-F47 WeakPolarHBondContact NE2-CD2 3.39Å; H43-F47 AromaticContact NE2-CE2 3.98Å; H43-F47 AromaticContact NE2-CG 3.91Å; H43-F47 WeakPolarHBondContact O-CD2 3.22Å; H43-F47 PolarHBondContact O-N 3.25Å; F47-Y49 VanDerWaalsContact C-N 3.27Å; F47-Y49 HydrophobicContact CB-CD1 3.87Å; F47-Y49 HydrophobicContact CB-CE1 3.63Å; F47-Y49 HydrophobicContact CG-CE1 4.45Å; F47-Y49 WeakPolarHBondContact O-CD1 3.4Å; F47-Y49 PolarHBondContact O-N 3.28Å; F47-Y75 HydrophobicContact CE2-CD2 4.47Å; F47-Y75 HydrophobicContact CE2-CG 4.36Å; F47-A79 HydrophobicContact CE1-CB 3.85Å; F47-A79 HydrophobicContact CZ-CB 4.06Å; F47-D84 HydrophobicContact CE1-CB 4.2Å; F47-D84 HydrophobicContact CZ-CB 4.18Å; F47-I89 HydrophobicContact CE2-CD1 3.89Å; F47-I89 HydrophobicContact CZ-CD1 3.66Å; F47-I89 HydrophobicContact CZ-CG1 4.44Å
48	G	95.4	Very high	94.7	Very high	67 Å²	67	46.9 Å²	46.9	69%	0.691	25%	0.251	S	S	*	.	S	Bend	trans	80.4	-2.2	175.9	0	0	0	0	0	115.3	K44	K44-G48 VanDerWaalsContact O-CA 3.3Å; K44-G48 WeakPolarHBondContact O-CA 3.17Å; K44-G48 PolarHBondContact O-N 3.28Å
49	Y	95.5	Very high	94.4	Very high	152 Å²	152	55 Å²	55	60%	0.596	29%	0.286	S	S	*	.			trans	-129.9	154.7	176.3	72.1	-87.2	0	0	0	111.9	H43 K44 F47	H43-Y49 AromaticContact CE1-CD2 4Å; H43-Y49 AromaticContact CE1-CE1 3.84Å; H43-Y49 AromaticContact CE1-CE2 3.45Å; H43-Y49 VanDerWaalsContact CE1-CE2 3.45Å; H43-Y49 WeakPolarHBondContact CE1-CE2 3.46Å; H43-Y49 AromaticContact CE1-CZ 3.34Å; H43-Y49 PolarHBondContact ND1-O 2.96Å; H43-Y49 AromaticContact NE2-CZ 3.85Å; K44-Y49 VanDerWaalsContact CA-O 3.28Å; K44-Y49 WeakPolarHBondContact CA-O 3.42Å; F47-Y49 VanDerWaalsContact C-N 3.27Å; F47-Y49 HydrophobicContact CB-CD1 3.87Å; F47-Y49 HydrophobicContact CB-CE1 3.63Å; F47-Y49 HydrophobicContact CG-CE1 4.45Å; F47-Y49 WeakPolarHBondContact O-CD1 3.4Å; F47-Y49 PolarHBondContact O-N 3.28Å
50	G	91.5	Very high	94.2	Very high	32 Å²	32	56.5 Å²	56.5	33%	0.33	29%	0.294	S	S	.	.			trans	130.5	170.4	-175.1	0	0	0	0	0	113.1	E40 K44	E40-G50 WeakPolarHBondContact OE1-CA 3.46Å; K44-G50 WeakPolarHBondContact CD-O 3.5Å; K44-G50 WeakPolarHBondContact CE-O 3.45Å; K44-G50 PolarHBondContact NZ-O 3.4Å
51	A	91.6	Very high	94	Very high	50 Å²	50	54.1 Å²	54.1	41%	0.413	28%	0.283	S	S	.	.			trans	-102.1	137.5	-176.6	0	0	0	0	0	111.8	W36 E40	W36-A51 HydrophobicContact CZ3-CB 4.16Å; E40-A51 WeakPolarHBondContact CG-O 3.41Å; E40-A51 PolarHBondContact OE1-N 2.84Å
52	L	94.5	Very high	93.8	Very high	67 Å²	67	54.3 Å²	54.3	35%	0.351	28%	0.283	S	S	.	.			trans	-107.7	137.3	168.6	-64.4	176.8	0	0	0	108.2	V41 K44 W56	V41-L52 HydrophobicContact CB-CD2 4.19Å; V41-L52 HydrophobicContact CG1-CD2 4.06Å; V41-L52 HydrophobicContact CG2-CD2 4.02Å; K44-L52 HydrophobicContact CD-CD1 3.85Å; K44-L52 HydrophobicContact CD-CD2 3.86Å; K44-L52 HydrophobicContact CD-CG 3.5Å; K44-L52 VanDerWaalsContact CD-CG 3.5Å; L52-W56 HydrophobicContact CB-CB 4.12Å; L52-W56 HydrophobicContact CD1-CB 4.42Å; L52-W56 HydrophobicContact CD2-CG 4.42Å
53	T	94.5	Very high	93.6	Very high	39 Å²	39	56.1 Å²	56.1	24%	0.239	29%	0.29	C	S	.	.			trans	-76.6	167.5	172.9	60.3	0	0	0	0	111	W36 E55 W56	W36-T53 HydrophobicContact CB-CG2 3.75Å; W36-T53 HydrophobicContact CD2-CG2 4.34Å; W36-T53 HydrophobicContact CE3-CG2 4.23Å; W36-T53 HydrophobicContact CG-CG2 4.18Å; T53-E55 PolarHBondContact O-N 2.88Å; T53-E55 VanDerWaalsContact O-N 3.08Å; T53-W56 PolarHBondContact O-N 2.9Å
54	W	93	Very high	93.5	Very high	105 Å²	105	55.7 Å²	55.7	40%	0.398	29%	0.29	S	S	.	.	G	3₁₀ helix	trans	-54.4	-26.1	176.2	63.7	-92.2	0	0	0	113.3	W56 E57 I60 L62 F284	W54-W56 PolarHBondContact O-N 3.21Å; W54-E57 WeakPolarHBondContact O-CB 3.48Å; W54-E57 PolarHBondContact O-N 3.39Å; W54-E57 VanDerWaalsContact O-N 3.12Å; W54-I60 HydrophobicContact CE3-CD1 3.77Å; W54-I60 HydrophobicContact CE3-CG2 4.15Å; W54-I60 HydrophobicContact CZ3-CD1 4.46Å; W54-I60 HydrophobicContact CZ3-CG2 4.07Å; W54-L62 HydrophobicContact CH2-CD2 3.95Å; W54-L62 HydrophobicContact CZ3-CD2 4.07Å; W54-F284 AromaticContact CH2-CE1 3.97Å; W54-F284 HydrophobicContact CH2-CE1 3.97Å; W54-F284 AromaticContact CH2-CE2 3.9Å; W54-F284 HydrophobicContact CH2-CE2 3.9Å; W54-F284 AromaticContact CH2-CZ 3.43Å; W54-F284 HydrophobicContact CH2-CZ 3.43Å; W54-F284 VanDerWaalsContact CH2-CZ 3.43Å; W54-F284 HydrophobicContact CZ2-CZ 4.41Å; W54-F284 AromaticContact CZ3-CE2 3.96Å; W54-F284 HydrophobicContact CZ3-CE2 3.96Å; W54-F284 AromaticContact CZ3-CZ 3.98Å; W54-F284 HydrophobicContact CZ3-CZ 3.98Å
55	E	91.9	Very high	93.4	Very high	13 Å²	13	52.5 Å²	52.5	6%	0.061	28%	0.276	C	S	.	.	G	3₁₀ helix	trans	-63.1	-22.7	178.2	-58.7	-170.1	143.6	0	0	113.2	Q37 T53 L62 R63	Q37-E55 WeakPolarHBondContact CG-OE2 3.15Å; Q37-E55 PolarHBondContact NE2-OE1 3.15Å; Q37-E55 PolarHBondContact NE2-OE2 3.01Å; T53-E55 PolarHBondContact O-N 2.88Å; T53-E55 VanDerWaalsContact O-N 3.08Å; E55-L62 HydrophobicContact CB-CB 4.25Å; E55-L62 HydrophobicContact CG-CD2 4.2Å; E55-L62 PolarHBondContact O-N 2.78Å; E55-R63 HydrophobicContact CB-CG 4.03Å; E55-R63 VanDerWaalsContact CD-NE 3.34Å; E55-R63 IonicContact OE1-CZ 3.47Å; E55-R63 IonicContact OE1-NE 3.21Å; E55-R63 PolarHBondContact OE1-NE 3.25Å; E55-R63 IonicContact OE1-NH2 2.81Å; E55-R63 PolarHBondContact OE1-NH2 3.02Å; E55-R63 IonicContact OE2-CZ 3.88Å; E55-R63 IonicContact OE2-NE 3.16Å; E55-R63 PolarHBondContact OE2-NE 3.46Å; E55-R63 IonicContact OE2-NH2 3.39Å
56	W	94.5	Very high	93.4	Very high	10 Å²	10	50.5 Å²	50.5	4%	0.038	27%	0.271	C	S	.	.	G	3₁₀ helix	trans	-100.5	-1.4	179.2	-63.7	95.9	0	0	0	113.4	W36 Q37 V41 W45 L52 T53 W54 R63 P68 F271	W36-W56 PolarHBondContact O-NE1 3.16Å; Q37-W56 WeakPolarHBondContact O-CZ2 3.44Å; V41-W56 HydrophobicContact CB-CZ2 4.33Å; V41-W56 HydrophobicContact CG1-CD2 3.99Å; V41-W56 HydrophobicContact CG1-CE3 4.07Å; V41-W56 HydrophobicContact CG1-CH2 4.1Å; V41-W56 HydrophobicContact CG1-CZ2 3.97Å; V41-W56 HydrophobicContact CG1-CZ3 4.13Å; V41-W56 HydrophobicContact CG2-CD2 4.04Å; V41-W56 HydrophobicContact CG2-CG 4.31Å; V41-W56 HydrophobicContact CG2-CZ2 3.76Å; W45-W56 HydrophobicContact CH2-CH2 4.49Å; W45-W56 HydrophobicContact CH2-CZ3 4.01Å; W45-W56 HydrophobicContact CZ2-CE3 4.2Å; W45-W56 AromaticContact CZ2-CZ3 3.98Å; W45-W56 HydrophobicContact CZ2-CZ3 3.98Å; L52-W56 HydrophobicContact CB-CB 4.12Å; L52-W56 HydrophobicContact CD1-CB 4.42Å; L52-W56 HydrophobicContact CD2-CG 4.42Å; T53-W56 PolarHBondContact O-N 2.9Å; W54-W56 PolarHBondContact O-N 3.21Å; W56-R63 HydrophobicContact CH2-CB 3.6Å; W56-R63 HydrophobicContact CZ2-CB 3.54Å; W56-R63 HydrophobicContact CZ2-CG 4.13Å; W56-R63 HydrophobicContact CZ3-CB 4.18Å; W56-P68 HydrophobicContact CH2-CG 3.56Å; W56-P68 HydrophobicContact CZ2-CG 3.86Å; W56-F271 AromaticContact CE3-CE1 4Å; W56-F271 HydrophobicContact CE3-CE1 4Å; W56-F271 AromaticContact CE3-CZ 3.88Å; W56-F271 HydrophobicContact CE3-CZ 3.88Å; W56-F271 HydrophobicContact CZ3-CZ 4.08Å; W56-F271 WeakPolarHBondContact O-CE1 3.43Å
57	E	92.9	Very high	93.4	Very high	84 Å²	84	49.4 Å²	49.4	39%	0.393	26%	0.264	S	S	.	.	S	Bend	trans	-63	132.4	175.5	-170.6	176.2	172	0	0	109.2	W54 K59 I60 A61	W54-E57 WeakPolarHBondContact O-CB 3.48Å; W54-E57 PolarHBondContact O-N 3.39Å; W54-E57 VanDerWaalsContact O-N 3.12Å; E57-K59 PolarHBondContact O-N 2.9Å; E57-K59 IonicContact OE1-NZ 3.97Å; E57-I60 PolarHBondContact O-N 2.99Å; E57-A61 PolarHBondContact O-N 2.82Å
58	P	90.2	Very high	93.4	Very high	53 Å²	53	47.1 Å²	47.1	34%	0.344	25%	0.254	S	S	.	.	T	Hydrogen-bonded Turn	trans	-53.6	-30.1	-176.2	-30.7	36.3	0	0	0	114.8	I60 F271 I275	P58-I60 VanDerWaalsContact C-N 3.26Å; P58-I60 PolarHBondContact O-N 3.27Å; P58-F271 HydrophobicContact CB-CB 4.41Å; P58-I275 WeakPolarHBondContact O-CD1 3.29Å
59	K	88.8	Confident	93.5	Very high	172 Å²	172	45.9 Å²	45.9	75%	0.748	23%	0.232	S	C	*	.	T	Hydrogen-bonded Turn	trans	-68.1	-24	177.1	-64	177.7	-175.6	164.7	0	113.6	E57	E57-K59 PolarHBondContact O-N 2.9Å; E57-K59 IonicContact OE1-NZ 3.97Å
60	I	90.2	Very high	93.5	Very high	55 Å²	55	41.9 Å²	41.9	28%	0.282	22%	0.22	S	C	.	.	T	Hydrogen-bonded Turn	trans	-108.5	-53.4	-175.4	-57.9	-179.2	0	0	0	109.9	W54 E57 P58 L62 N280	W54-I60 HydrophobicContact CE3-CD1 3.77Å; W54-I60 HydrophobicContact CE3-CG2 4.15Å; W54-I60 HydrophobicContact CZ3-CD1 4.46Å; W54-I60 HydrophobicContact CZ3-CG2 4.07Å; E57-I60 PolarHBondContact O-N 2.99Å; P58-I60 VanDerWaalsContact C-N 3.26Å; P58-I60 PolarHBondContact O-N 3.27Å; I60-L62 HydrophobicContact CG2-CB 4.1Å; I60-L62 PolarHBondContact O-N 3.18Å; I60-N280 PolarHBondContact O-ND2 2.99Å
61	A	92.5	Very high	93.8	Very high	0 Å²	0	40.4 Å²	40.4	0%	0	21%	0.205	C	C	.	.			trans	41.7	60.2	176.2	0	0	0	0	0	112.4	E57 F271 I275	E57-A61 PolarHBondContact O-N 2.82Å; A61-F271 HydrophobicContact CB-CD1 3.84Å; A61-F271 HydrophobicContact CB-CD2 3.87Å; A61-F271 HydrophobicContact CB-CE1 3.83Å; A61-F271 HydrophobicContact CB-CE2 3.87Å; A61-F271 HydrophobicContact CB-CG 3.86Å; A61-F271 HydrophobicContact CB-CZ 3.84Å; A61-I275 HydrophobicContact CB-CD1 3.57Å; A61-I275 HydrophobicContact CB-CG2 3.95Å
62	L	92.1	Very high	94.1	Very high	3 Å²	3	38.5 Å²	38.5	2%	0.016	19%	0.188	C	C	.	.			trans	-81.4	-24.2	-169.8	-168.6	65.6	0	0	0	112.9	W54 E55 I60 F281 F284	W54-L62 HydrophobicContact CH2-CD2 3.95Å; W54-L62 HydrophobicContact CZ3-CD2 4.07Å; E55-L62 HydrophobicContact CB-CB 4.25Å; E55-L62 HydrophobicContact CG-CD2 4.2Å; E55-L62 PolarHBondContact O-N 2.78Å; I60-L62 HydrophobicContact CG2-CB 4.1Å; I60-L62 PolarHBondContact O-N 3.18Å; L62-F281 HydrophobicContact CD1-CB 4.37Å; L62-F284 HydrophobicContact CD1-CB 3.58Å; L62-F284 HydrophobicContact CD1-CD1 4.09Å; L62-F284 HydrophobicContact CD1-CG 3.86Å; L62-F284 HydrophobicContact CD2-CD1 3.98Å; L62-F284 HydrophobicContact CD2-CE1 4.23Å; L62-F284 HydrophobicContact CD2-CG 4.37Å
63	R	93.7	Very high	94.2	Very high	39 Å²	39	41.9 Å²	41.9	15%	0.147	20%	0.201	C	C	.	.	S	Bend	trans	-112.7	145.2	-168.7	-57.9	-62.7	178.4	-176.7	-8.3	111	Q37 E55 W56	Q37-R63 VanDerWaalsContact CD-CZ 3.49Å; Q37-R63 HydrophobicContact CG-CG 4.48Å; E55-R63 HydrophobicContact CB-CG 4.03Å; E55-R63 VanDerWaalsContact CD-NE 3.34Å; E55-R63 IonicContact OE1-CZ 3.47Å; E55-R63 IonicContact OE1-NE 3.21Å; E55-R63 PolarHBondContact OE1-NE 3.25Å; E55-R63 IonicContact OE1-NH2 2.81Å; E55-R63 PolarHBondContact OE1-NH2 3.02Å; E55-R63 IonicContact OE2-CZ 3.88Å; E55-R63 IonicContact OE2-NE 3.16Å; E55-R63 PolarHBondContact OE2-NE 3.46Å; E55-R63 IonicContact OE2-NH2 3.39Å; W56-R63 HydrophobicContact CH2-CB 3.6Å; W56-R63 HydrophobicContact CZ2-CB 3.54Å; W56-R63 HydrophobicContact CZ2-CG 4.13Å; W56-R63 HydrophobicContact CZ3-CB 4.18Å
64	S	94.5	Very high	94.4	Very high	12 Å²	12	42.1 Å²	42.1	8%	0.084	20%	0.2	C	C	.	.			trans	-75.4	129.3	175.9	178.9	0	0	0	0	110.8	V66 P68 L194 N277	S64-V66 PolarHBondContact O-N 3.4Å; S64-V66 WeakPolarHBondContact OG-CG2 3.4Å; S64-P68 WeakPolarHBondContact O-CD 3.47Å; S64-L194 WeakPolarHBondContact CB-O 3.5Å; S64-L194 PolarHBondContact OG-O 2.96Å; S64-N277 WeakPolarHBondContact CA-ND2 3.46Å
65	P	95.3	Very high	94.6	Very high	0 Å²	0	37.1 Å²	37.1	0%	0	18%	0.181	C	C	.	.	T	Hydrogen-bonded Turn	trans	-71.4	-13.9	178.9	29.2	-34.9	0	0	0	113	W45 H67 P68 L69 L266 D267 T270	W45-P65 HydrophobicContact CH2-CB 3.72Å; W45-P65 HydrophobicContact CZ3-CB 4.41Å; P65-H67 VanDerWaalsContact C-N 3.35Å; P65-H67 PolarHBondContact O-N 2.85Å; P65-P68 WeakPolarHBondContact O-CD 3.16Å; P65-L69 HydrophobicContact CB-CD1 4.3Å; P65-L69 VanDerWaalsContact O-CB 3.23Å; P65-L69 WeakPolarHBondContact O-CB 3.23Å; P65-L69 WeakPolarHBondContact O-CG 3.34Å; P65-L69 PolarHBondContact O-N 3.44Å; P65-L266 HydrophobicContact CG-CB 3.99Å; P65-D267 WeakPolarHBondContact CD-OD1 3.13Å; P65-T270 HydrophobicContact CB-CG2 4.2Å; P65-T270 WeakPolarHBondContact CB-OG1 3.25Å
66	V	95.4	Very high	94.9	Very high	29 Å²	29	42 Å²	42	18%	0.176	20%	0.202	C	C	.	.	H	α-helix	trans	-56.6	-45.1	-174.8	178.2	0	0	0	0	112.2	S64 L70 I195 L266	S64-V66 PolarHBondContact O-N 3.4Å; S64-V66 WeakPolarHBondContact OG-CG2 3.4Å; V66-L70 PolarHBondContact O-N 3.38Å; V66-I195 HydrophobicContact CB-CG1 4.11Å; V66-I195 HydrophobicContact CG1-CD1 4.12Å; V66-I195 HydrophobicContact CG1-CG1 3.77Å; V66-L266 HydrophobicContact CG2-CD1 3.85Å
67	H	96.1	Very high	95.1	Very high	6 Å²	6	44.2 Å²	44.2	3%	0.028	22%	0.217	C	C	.	.	H	α-helix	trans	-71.6	-50.4	-177.4	171.2	-122.9	0	0	0	113.2	S38 P65 L69 L70 H97 S141 S143 I195	S38-H67 VanDerWaalsContact CB-CE1 3.48Å; S38-H67 WeakPolarHBondContact CB-CE1 3.24Å; P65-H67 VanDerWaalsContact C-N 3.35Å; P65-H67 PolarHBondContact O-N 2.85Å; H67-L69 PolarHBondContact O-N 3.48Å; H67-L70 WeakPolarHBondContact O-CB 3.26Å; H67-L70 PolarHBondContact O-N 3.43Å; H67-L70 VanDerWaalsContact O-N 3.16Å; H67-H97 AromaticContact CD2-NE2 3.87Å; H67-H97 AromaticContact CE1-NE2 3.87Å; H67-H97 AromaticContact NE2-CE1 3.39Å; H67-H97 PolarHBondContact NE2-CE1 2.85Å; H67-H97 AromaticContact NE2-NE2 2.92Å; H67-H97 PolarHBondContact NE2-NE2 2.7Å; H67-S141 PolarHBondContact CE1-O 3.16Å; H67-S143 PolarHBondContact CE1-N 2.97Å; H67-S143 VanDerWaalsContact CE1-N 3.28Å; H67-I195 HydrophobicContact CB-CG2 4.05Å
68	P	97.1	Very high	95.3	Very high	1 Å²	1	41 Å²	41	1%	0.006	20%	0.202	C	C	.	.	H	α-helix	trans	-62	-29.4	173.8	-19.6	28.6	0	0	0	113.2	Q37 V41 A42 W45 W56 S64 P65 L70 I71 S72	Q37-P68 WeakPolarHBondContact O-CG 3.38Å; V41-P68 HydrophobicContact CB-CB 4.15Å; V41-P68 HydrophobicContact CB-CG 4.44Å; V41-P68 HydrophobicContact CG1-CB 3.99Å; V41-P68 HydrophobicContact CG1-CG 4.25Å; A42-P68 HydrophobicContact CB-CB 4.37Å; A42-P68 WeakPolarHBondContact CB-O 3.48Å; W45-P68 HydrophobicContact CE3-CB 4.43Å; W45-P68 HydrophobicContact CH2-CB 4.03Å; W45-P68 HydrophobicContact CH2-CG 4.43Å; W45-P68 HydrophobicContact CZ3-CB 3.7Å; W56-P68 HydrophobicContact CH2-CG 3.56Å; W56-P68 HydrophobicContact CZ2-CG 3.86Å; S64-P68 WeakPolarHBondContact O-CD 3.47Å; P65-P68 WeakPolarHBondContact O-CD 3.16Å; P68-L70 VanDerWaalsContact C-N 3.32Å; P68-L70 PolarHBondContact O-N 3.32Å; P68-I71 PolarHBondContact O-N 3.36Å; P68-I71 VanDerWaalsContact O-N 3.16Å; P68-S72 WeakPolarHBondContact O-CB 3.29Å; P68-S72 PolarHBondContact O-N 3.19Å; P68-S72 PolarHBondContact O-OG 2.93Å
69	L	96.7	Very high	95.6	Very high	41 Å²	41	39.8 Å²	39.8	22%	0.215	20%	0.197	C	C	.	.	H	α-helix	trans	-62.6	-36.8	175	-84.1	175.3	0	0	0	112.5	W45 P65 H67 I71 S72 F73 L266 W269	W45-L69 HydrophobicContact CE3-CD2 3.94Å; W45-L69 HydrophobicContact CE3-CG 4.31Å; W45-L69 HydrophobicContact CZ3-CB 4.47Å; W45-L69 HydrophobicContact CZ3-CD2 3.84Å; W45-L69 HydrophobicContact CZ3-CG 3.69Å; P65-L69 HydrophobicContact CB-CD1 4.3Å; P65-L69 VanDerWaalsContact O-CB 3.23Å; P65-L69 WeakPolarHBondContact O-CB 3.23Å; P65-L69 WeakPolarHBondContact O-CG 3.34Å; P65-L69 PolarHBondContact O-N 3.44Å; H67-L69 PolarHBondContact O-N 3.48Å; L69-I71 VanDerWaalsContact C-N 3.28Å; L69-I71 PolarHBondContact O-N 2.98Å; L69-S72 PolarHBondContact O-N 2.88Å; L69-F73 PolarHBondContact O-N 3.47Å; L69-L266 HydrophobicContact CD1-CD1 4.11Å; L69-L266 HydrophobicContact CD1-CD2 3.9Å; L69-W269 HydrophobicContact CD1-CZ3 4.48Å; L69-W269 HydrophobicContact CD2-CH2 4.07Å; L69-W269 HydrophobicContact CD2-CZ3 3.72Å
70	L	96.4	Very high	96	Very high	68 Å²	68	36.3 Å²	36.3	36%	0.356	19%	0.19	S	C	.	.	H	α-helix	trans	-61	-39.9	174	-67.6	170.4	0	0	0	111.4	V66 H67 P68 L96	V66-L70 PolarHBondContact O-N 3.38Å; H67-L70 WeakPolarHBondContact O-CB 3.26Å; H67-L70 PolarHBondContact O-N 3.43Å; H67-L70 VanDerWaalsContact O-N 3.16Å; P68-L70 VanDerWaalsContact C-N 3.32Å; P68-L70 PolarHBondContact O-N 3.32Å; L70-L96 HydrophobicContact CB-CD2 4.39Å
71	I	98	Very high	96.3	Very high	1 Å²	1	40 Å²	40	1%	0.005	21%	0.209	C	C	.	.	H	α-helix	trans	-72.2	-41.6	177.1	-58.5	171.8	0	0	0	110.3	A42 P68 L69 F73 I74 Y75 P93 L96	A42-I71 HydrophobicContact CB-CB 3.72Å; A42-I71 HydrophobicContact CB-CG2 3.65Å; P68-I71 PolarHBondContact O-N 3.36Å; P68-I71 VanDerWaalsContact O-N 3.16Å; L69-I71 VanDerWaalsContact C-N 3.28Å; L69-I71 PolarHBondContact O-N 2.98Å; I71-F73 VanDerWaalsContact C-N 3.28Å; I71-F73 PolarHBondContact O-N 3.48Å; I71-I74 WeakPolarHBondContact O-CB 3.41Å; I71-I74 PolarHBondContact O-N 2.72Å; I71-I74 VanDerWaalsContact O-N 3.08Å; I71-Y75 HydrophobicContact CG2-CD2 4.07Å; I71-Y75 HydrophobicContact CG2-CE1 4.22Å; I71-Y75 HydrophobicContact CG2-CE2 3.69Å; I71-Y75 HydrophobicContact CG2-CG 4.5Å; I71-Y75 PolarHBondContact O-N 3.3Å; I71-P93 HydrophobicContact CD1-CB 4.39Å; I71-P93 HydrophobicContact CG2-CB 4.11Å; I71-P93 HydrophobicContact CG2-CG 3.87Å; I71-L96 HydrophobicContact CG1-CD2 4.39Å
72	S	97.6	Very high	96.4	Very high	10 Å²	10	42.8 Å²	42.8	7%	0.07	24%	0.238	C	C	.	.	H	α-helix	trans	-59.8	-40	178.7	-55.3	0	0	0	0	111.4	A42 V46 P68 L69 I74 Y75 K76	A42-S72 WeakPolarHBondContact CA-OG 3.32Å; A42-S72 VanDerWaalsContact CB-OG 3.26Å; A42-S72 WeakPolarHBondContact CB-OG 3.31Å; V46-S72 WeakPolarHBondContact CG2-O 3.39Å; P68-S72 WeakPolarHBondContact O-CB 3.29Å; P68-S72 PolarHBondContact O-N 3.19Å; P68-S72 PolarHBondContact O-OG 2.93Å; L69-S72 PolarHBondContact O-N 2.88Å; S72-I74 VanDerWaalsContact C-N 3.33Å; S72-I74 PolarHBondContact O-N 2.95Å; S72-Y75 PolarHBondContact O-N 3.14Å; S72-K76 WeakPolarHBondContact O-CB 3.32Å; S72-K76 PolarHBondContact O-N 2.97Å
73	F	97.7	Very high	96.6	Very high	139 Å²	139	44.5 Å²	44.5	61%	0.61	25%	0.253	S	S	*	.	H	α-helix	trans	-58.3	-46.6	174.9	176.1	-104.1	0	0	0	111.4	L69 I71 K76 V77	L69-F73 PolarHBondContact O-N 3.47Å; I71-F73 VanDerWaalsContact C-N 3.28Å; I71-F73 PolarHBondContact O-N 3.48Å; F73-K76 PolarHBondContact O-N 3.3Å; F73-V77 HydrophobicContact CE1-CG2 4.25Å; F73-V77 HydrophobicContact CE2-CG2 4.33Å; F73-V77 HydrophobicContact CZ-CG2 4.07Å; F73-V77 WeakPolarHBondContact O-CG2 3.31Å; F73-V77 PolarHBondContact O-N 3.17Å
74	I	97.5	Very high	96.6	Very high	44 Å²	44	46.2 Å²	46.2	23%	0.226	27%	0.265	C	S	.	.	H	α-helix	trans	-64.2	-43.9	177.6	-64.6	-57.1	0	0	0	111.6	I71 S72 K76 V77 I78 L96	I71-I74 WeakPolarHBondContact O-CB 3.41Å; I71-I74 PolarHBondContact O-N 2.72Å; I71-I74 VanDerWaalsContact O-N 3.08Å; S72-I74 VanDerWaalsContact C-N 3.33Å; S72-I74 PolarHBondContact O-N 2.95Å; I74-K76 VanDerWaalsContact C-N 3.31Å; I74-K76 PolarHBondContact O-N 3.06Å; I74-V77 PolarHBondContact O-N 2.84Å; I74-I78 HydrophobicContact CG2-CD1 3.62Å; I74-I78 HydrophobicContact CG2-CG1 4.43Å; I74-I78 WeakPolarHBondContact O-CD1 3.21Å; I74-I78 VanDerWaalsContact O-CG1 3.29Å; I74-I78 WeakPolarHBondContact O-CG1 3.49Å; I74-I78 PolarHBondContact O-N 3.13Å; I74-L96 HydrophobicContact CD1-CD1 4.32Å; I74-L96 HydrophobicContact CG1-CD1 4.08Å; I74-L96 HydrophobicContact CG1-CD2 3.93Å; I74-L96 HydrophobicContact CG1-CG 4.43Å
75	Y	98.2	Very high	96.6	Very high	0 Å²	0	48.8 Å²	48.8	0%	0	28%	0.283	C	S	.	.	H	α-helix	trans	-60	-41	174.3	-73	-14.4	0	0	0	112.7	I39 A42 H43 F47 I71 S72 V77 I78 A79 I89 S92 P93	I39-Y75 WeakPolarHBondContact CG2-OH 3.31Å; A42-Y75 HydrophobicContact CB-CD2 4.05Å; A42-Y75 HydrophobicContact CB-CE2 4.05Å; H43-Y75 HydrophobicContact CB-CD2 4.39Å; H43-Y75 HydrophobicContact CB-CE2 4Å; F47-Y75 HydrophobicContact CE2-CD2 4.47Å; F47-Y75 HydrophobicContact CE2-CG 4.36Å; I71-Y75 HydrophobicContact CG2-CD2 4.07Å; I71-Y75 HydrophobicContact CG2-CE1 4.22Å; I71-Y75 HydrophobicContact CG2-CE2 3.69Å; I71-Y75 HydrophobicContact CG2-CG 4.5Å; I71-Y75 PolarHBondContact O-N 3.3Å; S72-Y75 PolarHBondContact O-N 3.14Å; Y75-V77 PolarHBondContact O-N 3.21Å; Y75-I78 PolarHBondContact O-N 3.5Å; Y75-A79 WeakPolarHBondContact O-CB 3.1Å; Y75-A79 PolarHBondContact O-N 2.71Å; Y75-I89 HydrophobicContact CD1-CD1 3.88Å; Y75-I89 HydrophobicContact CE1-CB 4.42Å; Y75-I89 HydrophobicContact CE1-CD1 4.15Å; Y75-I89 HydrophobicContact CE1-CG2 3.92Å; Y75-I89 VanDerWaalsContact CE1-O 3.25Å; Y75-I89 WeakPolarHBondContact CE1-O 3.43Å; Y75-I89 HydrophobicContact CE2-CG2 4.45Å; Y75-I89 HydrophobicContact CG-CD1 4.43Å; Y75-I89 PolarHBondContact OH-O 2.65Å; Y75-S92 VanDerWaalsContact CE1-OG 3.31Å; Y75-S92 WeakPolarHBondContact CE1-OG 3.45Å; Y75-P93 HydrophobicContact CE1-CG 3.86Å; Y75-P93 WeakPolarHBondContact OH-CG 3.26Å
76	K	97.9	Very high	96.6	Very high	116 Å²	116	57.4 Å²	57.4	50%	0.504	32%	0.323	S	S	.	.	H	α-helix	trans	-63.3	-43.4	177.6	-172	62.3	176	-179.4	0	111.3	V46 S72 F73 I74 A79 T80	V46-K76 HydrophobicContact CG1-CB 4.31Å; V46-K76 HydrophobicContact CG1-CD 4.14Å; V46-K76 HydrophobicContact CG2-CB 4.31Å; S72-K76 WeakPolarHBondContact O-CB 3.32Å; S72-K76 PolarHBondContact O-N 2.97Å; F73-K76 PolarHBondContact O-N 3.3Å; I74-K76 VanDerWaalsContact C-N 3.31Å; I74-K76 PolarHBondContact O-N 3.06Å; K76-A79 PolarHBondContact O-N 2.84Å; K76-T80 VanDerWaalsContact O-CG2 3.31Å; K76-T80 WeakPolarHBondContact O-CG2 3.41Å; K76-T80 PolarHBondContact O-N 3.09Å; K76-T80 PolarHBondContact O-OG1 3.32Å; K76-T80 VanDerWaalsContact O-OG1 3.09Å
77	V	97.6	Very high	96.6	Very high	56 Å²	56	62.8 Å²	62.8	34%	0.339	34%	0.34	S	S	.	.	H	α-helix	trans	-59.7	-48.8	175.3	172.1	0	0	0	0	110.7	F73 I74 Y75 A79 T80 L81	F73-V77 HydrophobicContact CE1-CG2 4.25Å; F73-V77 HydrophobicContact CE2-CG2 4.33Å; F73-V77 HydrophobicContact CZ-CG2 4.07Å; F73-V77 WeakPolarHBondContact O-CG2 3.31Å; F73-V77 PolarHBondContact O-N 3.17Å; I74-V77 PolarHBondContact O-N 2.84Å; Y75-V77 PolarHBondContact O-N 3.21Å; V77-A79 VanDerWaalsContact C-N 3.35Å; V77-A79 PolarHBondContact O-N 3.49Å; V77-T80 WeakPolarHBondContact CA-OG1 3.12Å; V77-T80 PolarHBondContact O-N 3.05Å; V77-T80 PolarHBondContact O-OG1 3.41Å; V77-L81 HydrophobicContact CG1-CD1 3.95Å; V77-L81 VanDerWaalsContact O-CG 3.31Å; V77-L81 WeakPolarHBondContact O-CG 3.38Å; V77-L81 PolarHBondContact O-N 2.86Å
78	I	97.1	Very high	96.5	Very high	15 Å²	15	65.4 Å²	65.4	8%	0.077	35%	0.353	C	S	.	.	H	α-helix	trans	-60.4	-44.4	179.5	-69.3	161.7	0	0	0	111.4	I74 Y75 L81 G82 A83 D84 M88 I89 S92	I74-I78 HydrophobicContact CG2-CD1 3.62Å; I74-I78 HydrophobicContact CG2-CG1 4.43Å; I74-I78 WeakPolarHBondContact O-CD1 3.21Å; I74-I78 VanDerWaalsContact O-CG1 3.29Å; I74-I78 WeakPolarHBondContact O-CG1 3.49Å; I74-I78 PolarHBondContact O-N 3.13Å; Y75-I78 PolarHBondContact O-N 3.5Å; I78-L81 PolarHBondContact O-N 3.27Å; I78-G82 PolarHBondContact O-N 3.44Å; I78-A83 VanDerWaalsContact CG2-C 3.45Å; I78-A83 HydrophobicContact CG2-CB 4.23Å; I78-A83 WeakPolarHBondContact CG2-O 3.25Å; I78-A83 PolarHBondContact O-N 3.09Å; I78-D84 HydrophobicContact CG2-CB 4.06Å; I78-M88 HydrophobicContact CD1-CG 3.92Å; I78-M88 HydrophobicContact CD1-SD 4.48Å; I78-M88 HydrophobicContact CG1-CG 4.23Å; I78-M88 HydrophobicContact CG2-CG 3.69Å; I78-I89 HydrophobicContact CG2-CD1 4.19Å; I78-S92 VanDerWaalsContact CD1-CB 3.42Å; I78-S92 WeakPolarHBondContact CD1-OG 3.14Å
79	A	96.8	Very high	96.5	Very high	29 Å²	29	66.3 Å²	66.3	24%	0.24	36%	0.358	C	S	.	.	H	α-helix	trans	-64.4	-41.6	177.4	0	0	0	0	0	111.9	V46 F47 Y75 K76 V77 L81 G82	V46-A79 HydrophobicContact CG1-CB 4.48Å; F47-A79 HydrophobicContact CE1-CB 3.85Å; F47-A79 HydrophobicContact CZ-CB 4.06Å; Y75-A79 WeakPolarHBondContact O-CB 3.1Å; Y75-A79 PolarHBondContact O-N 2.71Å; K76-A79 PolarHBondContact O-N 2.84Å; V77-A79 VanDerWaalsContact C-N 3.35Å; V77-A79 PolarHBondContact O-N 3.49Å; A79-L81 PolarHBondContact O-N 3.18Å; A79-G82 PolarHBondContact O-N 3.27Å; A79-G82 VanDerWaalsContact O-N 3.09Å
80	T	96.8	Very high	96.3	Very high	99 Å²	99	69.5 Å²	69.5	61%	0.607	37%	0.373	S	S	*	.	H	α-helix	trans	-66.2	-26.3	176.4	52.4	0	0	0	0	113.4	K76 V77 G82	K76-T80 VanDerWaalsContact O-CG2 3.31Å; K76-T80 WeakPolarHBondContact O-CG2 3.41Å; K76-T80 PolarHBondContact O-N 3.09Å; K76-T80 PolarHBondContact O-OG1 3.32Å; K76-T80 VanDerWaalsContact O-OG1 3.09Å; V77-T80 WeakPolarHBondContact CA-OG1 3.12Å; V77-T80 PolarHBondContact O-N 3.05Å; V77-T80 PolarHBondContact O-OG1 3.41Å; T80-G82 VanDerWaalsContact C-N 3.34Å
81	L	96.8	Very high	96.2	Very high	132 Å²	132	66.8 Å²	66.8	69%	0.691	36%	0.358	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.3	-5.4	174.9	-66.1	172.9	0	0	0	113	V77 I78 A79 A83	V77-L81 HydrophobicContact CG1-CD1 3.95Å; V77-L81 VanDerWaalsContact O-CG 3.31Å; V77-L81 WeakPolarHBondContact O-CG 3.38Å; V77-L81 PolarHBondContact O-N 2.86Å; I78-L81 PolarHBondContact O-N 3.27Å; A79-L81 PolarHBondContact O-N 3.18Å; L81-A83 VanDerWaalsContact C-N 3.25Å; L81-A83 HydrophobicContact CB-CB 4.5Å; L81-A83 PolarHBondContact O-N 3.18Å
82	G	95.6	Very high	96.1	Very high	59 Å²	59	67 Å²	67	61%	0.608	36%	0.36	S	S	*	.	T	Hydrogen-bonded Turn	trans	65.9	25.4	-175.1	0	0	0	0	0	113.9	I78 A79 T80	I78-G82 PolarHBondContact O-N 3.44Å; A79-G82 PolarHBondContact O-N 3.27Å; A79-G82 VanDerWaalsContact O-N 3.09Å; T80-G82 VanDerWaalsContact C-N 3.34Å
83	A	94.7	Very high	96.1	Very high	39 Å²	39	66.6 Å²	66.6	32%	0.322	36%	0.357	S	S	.	.			trans	-104.4	19	-178.1	0	0	0	0	0	112.8	I78 L81 S85 M88	I78-A83 VanDerWaalsContact CG2-C 3.45Å; I78-A83 HydrophobicContact CG2-CB 4.23Å; I78-A83 WeakPolarHBondContact CG2-O 3.25Å; I78-A83 PolarHBondContact O-N 3.09Å; L81-A83 VanDerWaalsContact C-N 3.25Å; L81-A83 HydrophobicContact CB-CB 4.5Å; L81-A83 PolarHBondContact O-N 3.18Å; A83-S85 PolarHBondContact O-N 3.26Å; A83-M88 HydrophobicContact CB-CE 4.41Å; A83-M88 VanDerWaalsContact O-CB 3.26Å; A83-M88 WeakPolarHBondContact O-CB 3.48Å; A83-M88 WeakPolarHBondContact O-CG 3.28Å
84	D	94.2	Very high	96.1	Very high	75 Å²	75	60.7 Å²	60.7	40%	0.401	33%	0.332	S	S	.	.			trans	-78.9	35	-171.6	58.6	-34.5	0	0	0	114.7	F47 I78 I89	F47-D84 HydrophobicContact CE1-CB 4.2Å; F47-D84 HydrophobicContact CZ-CB 4.18Å; I78-D84 HydrophobicContact CG2-CB 4.06Å; D84-I89 HydrophobicContact CB-CD1 4.14Å; D84-I89 HydrophobicContact CB-CG1 4.42Å
85	S	96	Very high	96.1	Very high	65 Å²	65	60.7 Å²	60.7	46%	0.455	33%	0.331	S	S	.	.			trans	-55.8	150.2	168.9	68.4	0	0	0	0	111.6	A83 W87 M88 I89	A83-S85 PolarHBondContact O-N 3.26Å; S85-W87 PolarHBondContact O-N 2.86Å; S85-W87 VanDerWaalsContact O-N 3.14Å; S85-M88 WeakPolarHBondContact O-CB 3.31Å; S85-M88 PolarHBondContact O-N 2.89Å; S85-M88 WeakPolarHBondContact OG-CB 3.38Å; S85-M88 PolarHBondContact OG-N 3.39Å; S85-I89 PolarHBondContact O-N 2.85Å
86	Q	94.4	Very high	96.1	Very high	182 Å²	182	61.8 Å²	61.8	85%	0.85	34%	0.337	S	S	*	.	H	α-helix	trans	-51.6	-41.3	178.3	-69.1	-179.3	-17.5	0	0	112.5	I89 M90	Q86-I89 PolarHBondContact O-N 3.42Å; Q86-M90 WeakPolarHBondContact O-CB 3.44Å; Q86-M90 PolarHBondContact O-N 3.33Å
87	W	95.1	Very high	96.1	Very high	142 Å²	142	56.4 Å²	56.4	54%	0.538	31%	0.314	S	S	.	.	H	α-helix	trans	-62.2	-44.8	177.4	-175.7	92.9	0	0	0	111.9	L24 S85 M90 K91	L24-W87 HydrophobicContact CD2-CH2 4.02Å; L24-W87 HydrophobicContact CD2-CZ2 4.07Å; S85-W87 PolarHBondContact O-N 2.86Å; S85-W87 VanDerWaalsContact O-N 3.14Å; W87-M90 PolarHBondContact O-N 2.96Å; W87-K91 HydrophobicContact CD2-CG 4.22Å; W87-K91 HydrophobicContact CH2-CB 4.42Å; W87-K91 HydrophobicContact CH2-CG 4.45Å; W87-K91 HydrophobicContact CZ2-CB 4.43Å; W87-K91 HydrophobicContact CZ2-CG 3.96Å; W87-K91 WeakPolarHBondContact O-CB 3.32Å; W87-K91 PolarHBondContact O-N 2.84Å
88	M	95.3	Very high	96.1	Very high	60 Å²	60	53.7 Å²	53.7	30%	0.296	30%	0.298	S	S	.	.	H	α-helix	trans	-65.7	-42.3	179.5	-173.4	66.5	108.7	0	0	111.5	I78 A83 S85 M90 K91 S92	I78-M88 HydrophobicContact CD1-CG 3.92Å; I78-M88 HydrophobicContact CD1-SD 4.48Å; I78-M88 HydrophobicContact CG1-CG 4.23Å; I78-M88 HydrophobicContact CG2-CG 3.69Å; A83-M88 HydrophobicContact CB-CE 4.41Å; A83-M88 VanDerWaalsContact O-CB 3.26Å; A83-M88 WeakPolarHBondContact O-CB 3.48Å; A83-M88 WeakPolarHBondContact O-CG 3.28Å; S85-M88 WeakPolarHBondContact O-CB 3.31Å; S85-M88 PolarHBondContact O-N 2.89Å; S85-M88 WeakPolarHBondContact OG-CB 3.38Å; S85-M88 PolarHBondContact OG-N 3.39Å; M88-M90 VanDerWaalsContact C-N 3.34Å; M88-M90 PolarHBondContact O-N 3.13Å; M88-K91 PolarHBondContact O-N 3.17Å; M88-S92 WeakPolarHBondContact O-CB 3.39Å; M88-S92 PolarHBondContact O-N 3.43Å; M88-S92 PolarHBondContact O-OG 3.09Å
89	I	95.2	Very high	96.1	Very high	20 Å²	20	57.3 Å²	57.3	10%	0.103	31%	0.313	C	S	.	.	H	α-helix	trans	-64.8	-38.3	176.7	-63	-56.2	0	0	0	111.6	F47 Y75 I78 D84 S85 Q86 P93	F47-I89 HydrophobicContact CE2-CD1 3.89Å; F47-I89 HydrophobicContact CZ-CD1 3.66Å; F47-I89 HydrophobicContact CZ-CG1 4.44Å; Y75-I89 HydrophobicContact CD1-CD1 3.88Å; Y75-I89 HydrophobicContact CE1-CB 4.42Å; Y75-I89 HydrophobicContact CE1-CD1 4.15Å; Y75-I89 HydrophobicContact CE1-CG2 3.92Å; Y75-I89 VanDerWaalsContact CE1-O 3.25Å; Y75-I89 WeakPolarHBondContact CE1-O 3.43Å; Y75-I89 HydrophobicContact CE2-CG2 4.45Å; Y75-I89 HydrophobicContact CG-CD1 4.43Å; Y75-I89 PolarHBondContact OH-O 2.65Å; I78-I89 HydrophobicContact CG2-CD1 4.19Å; D84-I89 HydrophobicContact CB-CD1 4.14Å; D84-I89 HydrophobicContact CB-CG1 4.42Å; S85-I89 PolarHBondContact O-N 2.85Å; Q86-I89 PolarHBondContact O-N 3.42Å; I89-P93 VanDerWaalsContact O-CD 3.22Å; I89-P93 WeakPolarHBondContact O-CD 3.48Å
90	M	92.9	Very high	96.2	Very high	108 Å²	108	58.5 Å²	58.5	53%	0.532	31%	0.313	S	S	.	.	H	α-helix	trans	-70	-41.3	176.9	-176.4	-177.6	63.1	0	0	112.6	Q86 W87 M88	Q86-M90 WeakPolarHBondContact O-CB 3.44Å; Q86-M90 PolarHBondContact O-N 3.33Å; W87-M90 PolarHBondContact O-N 2.96Å; M88-M90 VanDerWaalsContact C-N 3.34Å; M88-M90 PolarHBondContact O-N 3.13Å
91	K	95.3	Very high	96.3	Very high	11 Å²	11	53.8 Å²	53.8	5%	0.048	28%	0.284	C	S	.	.	H	α-helix	trans	-89.6	-27.5	-173.3	-73.8	-58.9	-169.9	173.8	0	115	A23 L24 I26 W87 M88 P93 Q94 I95	A23-K91 PolarHBondContact O-NZ 2.9Å; L24-K91 PolarHBondContact O-NZ 3.38Å; L24-K91 VanDerWaalsContact O-NZ 3.09Å; I26-K91 PolarHBondContact O-NZ 3.43Å; W87-K91 HydrophobicContact CD2-CG 4.22Å; W87-K91 HydrophobicContact CH2-CB 4.42Å; W87-K91 HydrophobicContact CH2-CG 4.45Å; W87-K91 HydrophobicContact CZ2-CB 4.43Å; W87-K91 HydrophobicContact CZ2-CG 3.96Å; W87-K91 WeakPolarHBondContact O-CB 3.32Å; W87-K91 PolarHBondContact O-N 2.84Å; M88-K91 PolarHBondContact O-N 3.17Å; K91-P93 VanDerWaalsContact C-CD 3.48Å; K91-Q94 VanDerWaalsContact CD-OE1 3.28Å; K91-Q94 WeakPolarHBondContact O-CB 3.38Å; K91-Q94 PolarHBondContact O-N 3.06Å; K91-I95 HydrophobicContact CB-CD1 4.22Å; K91-I95 WeakPolarHBondContact O-CG1 3.41Å; K91-I95 PolarHBondContact O-N 3.31Å
92	S	96.5	Very high	96.4	Very high	7 Å²	7	47.5 Å²	47.5	5%	0.049	25%	0.251	C	S	.	.	H	α-helix	trans	-59.9	-37.1	-177.1	52.3	0	0	0	0	115	Y75 I78 M88 Q94 I95 L96	Y75-S92 VanDerWaalsContact CE1-OG 3.31Å; Y75-S92 WeakPolarHBondContact CE1-OG 3.45Å; I78-S92 VanDerWaalsContact CD1-CB 3.42Å; I78-S92 WeakPolarHBondContact CD1-OG 3.14Å; M88-S92 WeakPolarHBondContact O-CB 3.39Å; M88-S92 PolarHBondContact O-N 3.43Å; M88-S92 PolarHBondContact O-OG 3.09Å; S92-Q94 VanDerWaalsContact C-N 3.3Å; S92-Q94 PolarHBondContact O-N 3.38Å; S92-I95 PolarHBondContact O-N 2.6Å; S92-L96 WeakPolarHBondContact O-CB 3.22Å; S92-L96 PolarHBondContact O-N 3.08Å
93	P	96.8	Very high	96.5	Very high	1 Å²	1	46.3 Å²	46.3	1%	0.006	23%	0.23	C	C	.	.	H	α-helix	trans	-63.3	-39.1	173.6	-20.4	33.2	0	0	0	111.6	I39 I71 Y75 I89 K91 L96 H97	I39-P93 HydrophobicContact CD1-CG 4.47Å; I39-P93 HydrophobicContact CG1-CB 4.25Å; I39-P93 HydrophobicContact CG1-CG 4.16Å; I71-P93 HydrophobicContact CD1-CB 4.39Å; I71-P93 HydrophobicContact CG2-CB 4.11Å; I71-P93 HydrophobicContact CG2-CG 3.87Å; Y75-P93 HydrophobicContact CE1-CG 3.86Å; Y75-P93 WeakPolarHBondContact OH-CG 3.26Å; I89-P93 VanDerWaalsContact O-CD 3.22Å; I89-P93 WeakPolarHBondContact O-CD 3.48Å; K91-P93 VanDerWaalsContact C-CD 3.48Å; P93-L96 WeakPolarHBondContact O-CB 3.47Å; P93-L96 PolarHBondContact O-N 3.36Å; P93-H97 PolarHBondContact O-N 3.1Å; P93-H97 PolarHBondContact O-ND1 3.19Å
94	Q	96.7	Very high	96.7	Very high	15 Å²	15	44.5 Å²	44.5	7%	0.07	22%	0.215	C	C	.	.	H	α-helix	trans	-68.9	-40.3	179	-65	-179.9	-25	0	0	111.5	A23 K91 S92 L96 H97 G98 P139	A23-Q94 HydrophobicContact CB-CB 4.15Å; A23-Q94 WeakPolarHBondContact CB-O 3.33Å; A23-Q94 PolarHBondContact O-OE1 3.3Å; K91-Q94 VanDerWaalsContact CD-OE1 3.28Å; K91-Q94 WeakPolarHBondContact O-CB 3.38Å; K91-Q94 PolarHBondContact O-N 3.06Å; S92-Q94 VanDerWaalsContact C-N 3.3Å; S92-Q94 PolarHBondContact O-N 3.38Å; Q94-L96 VanDerWaalsContact C-N 3.35Å; Q94-H97 PolarHBondContact O-N 3.28Å; Q94-G98 PolarHBondContact O-N 2.94Å; Q94-P139 WeakPolarHBondContact CA-O 3.5Å; Q94-P139 WeakPolarHBondContact CB-O 3.42Å
95	I	97.6	Very high	96.9	Very high	43 Å²	43	40.9 Å²	40.9	22%	0.221	20%	0.196	C	C	.	.	H	α-helix	trans	-62.4	-43.3	174.6	-68	165.1	0	0	0	110.5	F20 A23 L24 K91 S92 H97 G98 F99	F20-I95 HydrophobicContact CD2-CG1 4.44Å; F20-I95 HydrophobicContact CD2-CG2 4.01Å; F20-I95 HydrophobicContact CE2-CD1 4.18Å; F20-I95 HydrophobicContact CE2-CG1 4.22Å; F20-I95 HydrophobicContact CE2-CG2 4.07Å; A23-I95 HydrophobicContact CB-CG1 4.39Å; L24-I95 HydrophobicContact CD2-CD1 4.1Å; L24-I95 HydrophobicContact CD2-CG1 4.3Å; K91-I95 HydrophobicContact CB-CD1 4.22Å; K91-I95 WeakPolarHBondContact O-CG1 3.41Å; K91-I95 PolarHBondContact O-N 3.31Å; S92-I95 PolarHBondContact O-N 2.6Å; I95-H97 PolarHBondContact O-N 3.38Å; I95-G98 PolarHBondContact O-N 2.96Å; I95-F99 PolarHBondContact O-N 3.08Å
96	L	97.9	Very high	97	Very high	24 Å²	24	38.8 Å²	38.8	13%	0.126	18%	0.179	C	C	.	.	H	α-helix	trans	-59.4	-45.5	175	178.2	67.8	0	0	0	111.7	L70 I71 I74 S92 P93 Q94 F99 F100	L70-L96 HydrophobicContact CB-CD2 4.39Å; I71-L96 HydrophobicContact CG1-CD2 4.39Å; I74-L96 HydrophobicContact CD1-CD1 4.32Å; I74-L96 HydrophobicContact CG1-CD1 4.08Å; I74-L96 HydrophobicContact CG1-CD2 3.93Å; I74-L96 HydrophobicContact CG1-CG 4.43Å; S92-L96 WeakPolarHBondContact O-CB 3.22Å; S92-L96 PolarHBondContact O-N 3.08Å; P93-L96 WeakPolarHBondContact O-CB 3.47Å; P93-L96 PolarHBondContact O-N 3.36Å; Q94-L96 VanDerWaalsContact C-N 3.35Å; L96-F99 WeakPolarHBondContact O-CB 3.37Å; L96-F99 PolarHBondContact O-N 2.8Å; L96-F100 HydrophobicContact CD1-CD2 4.24Å; L96-F100 HydrophobicContact CD1-CE2 3.63Å; L96-F100 HydrophobicContact CD1-CZ 4.34Å; L96-F100 HydrophobicContact CD2-CE2 4.32Å; L96-F100 HydrophobicContact CG-CD2 4.11Å; L96-F100 HydrophobicContact CG-CE2 3.76Å; L96-F100 VanDerWaalsContact O-CD2 3.23Å; L96-F100 WeakPolarHBondContact O-CD2 3.4Å; L96-F100 PolarHBondContact O-N 2.9Å; L96-F100 VanDerWaalsContact O-N 3.1Å
97	H	98	Very high	97.2	Very high	2 Å²	2	31.1 Å²	31.1	1%	0.009	14%	0.143	C	C	.	.	H	α-helix	trans	-69.5	-35.8	177.9	-73.4	66.9	0	0	0	111.7	H67 P93 Q94 I95 F99 F100 A101 R140	H67-H97 AromaticContact CD2-NE2 3.87Å; H67-H97 AromaticContact CE1-NE2 3.87Å; H67-H97 AromaticContact NE2-CE1 3.39Å; H67-H97 PolarHBondContact NE2-CE1 2.85Å; H67-H97 AromaticContact NE2-NE2 2.92Å; H67-H97 PolarHBondContact NE2-NE2 2.7Å; P93-H97 PolarHBondContact O-N 3.1Å; P93-H97 PolarHBondContact O-ND1 3.19Å; Q94-H97 PolarHBondContact O-N 3.28Å; I95-H97 PolarHBondContact O-N 3.38Å; H97-F99 VanDerWaalsContact C-N 3.31Å; H97-F99 PolarHBondContact O-N 3.21Å; H97-F100 PolarHBondContact O-N 3.2Å; H97-A101 WeakPolarHBondContact O-CB 3.48Å; H97-A101 PolarHBondContact O-N 3.24Å; H97-R140 PolarHBondContact CD2-O 2.91Å
98	G	98.2	Very high	97.4	Very high	0 Å²	0	24.5 Å²	24.5	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-58.9	-41.3	170.3	0	0	0	0	0	112.4	R19 Q94 I95 A101 A102	R19-G98 WeakPolarHBondContact CB-O 3.37Å; Q94-G98 PolarHBondContact O-N 2.94Å; I95-G98 PolarHBondContact O-N 2.96Å; G98-A101 PolarHBondContact O-N 3.39Å; G98-A102 PolarHBondContact O-N 3.42Å
99	F	98.3	Very high	97.5	Very high	90 Å²	90	22.2 Å²	22.2	40%	0.395	11%	0.106	S	C	.	.	H	α-helix	trans	-60.7	-49.3	173.5	173.1	-99.3	0	0	0	111.9	L16 I95 L96 H97 A101 A102 I103	L16-F99 HydrophobicContact CD1-CD2 3.63Å; L16-F99 HydrophobicContact CD1-CE2 4.34Å; I95-F99 PolarHBondContact O-N 3.08Å; L96-F99 WeakPolarHBondContact O-CB 3.37Å; L96-F99 PolarHBondContact O-N 2.8Å; H97-F99 VanDerWaalsContact C-N 3.31Å; H97-F99 PolarHBondContact O-N 3.21Å; F99-A101 VanDerWaalsContact C-N 3.31Å; F99-A101 PolarHBondContact O-N 3.4Å; F99-A102 PolarHBondContact O-N 3.43Å; F99-I103 HydrophobicContact CD1-CD1 4Å; F99-I103 HydrophobicContact CE1-CD1 3.44Å; F99-I103 VanDerWaalsContact CE1-CD1 3.44Å; F99-I103 HydrophobicContact CE2-CD1 4.37Å; F99-I103 HydrophobicContact CZ-CD1 3.66Å; F99-I103 PolarHBondContact O-N 2.73Å
100	F	98.4	Very high	97.5	Very high	54 Å²	54	25.4 Å²	25.4	24%	0.237	12%	0.119	C	C	.	.	H	α-helix	trans	-62.5	-37.5	175.5	-73.5	-61.2	0	0	0	112.7	L96 H97 A102 I103 A104 I146	L96-F100 HydrophobicContact CD1-CD2 4.24Å; L96-F100 HydrophobicContact CD1-CE2 3.63Å; L96-F100 HydrophobicContact CD1-CZ 4.34Å; L96-F100 HydrophobicContact CD2-CE2 4.32Å; L96-F100 HydrophobicContact CG-CD2 4.11Å; L96-F100 HydrophobicContact CG-CE2 3.76Å; L96-F100 VanDerWaalsContact O-CD2 3.23Å; L96-F100 WeakPolarHBondContact O-CD2 3.4Å; L96-F100 PolarHBondContact O-N 2.9Å; L96-F100 VanDerWaalsContact O-N 3.1Å; H97-F100 PolarHBondContact O-N 3.2Å; F100-A102 VanDerWaalsContact C-N 3.34Å; F100-A102 PolarHBondContact O-N 3.28Å; F100-I103 HydrophobicContact CD1-CD1 4.48Å; F100-I103 WeakPolarHBondContact O-CB 3.26Å; F100-I103 PolarHBondContact O-N 2.92Å; F100-A104 PolarHBondContact O-N 3.16Å; F100-I146 HydrophobicContact CB-CD1 4.3Å; F100-I146 HydrophobicContact CD2-CD1 3.74Å; F100-I146 HydrophobicContact CE2-CD1 4.36Å; F100-I146 HydrophobicContact CG-CD1 4.18Å
101	A	98.5	Very high	97.6	Very high	0 Å²	0	20.6 Å²	20.6	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-63.4	-38.7	175.8	0	0	0	0	0	112.1	R19 H97 G98 F99 I103 A104 D105 A138 W148	R19-A101 HydrophobicContact CG-CB 4.14Å; H97-A101 WeakPolarHBondContact O-CB 3.48Å; H97-A101 PolarHBondContact O-N 3.24Å; G98-A101 PolarHBondContact O-N 3.39Å; F99-A101 VanDerWaalsContact C-N 3.31Å; F99-A101 PolarHBondContact O-N 3.4Å; A101-I103 VanDerWaalsContact C-N 3.33Å; A101-I103 PolarHBondContact O-N 3.16Å; A101-A104 PolarHBondContact O-N 3.45Å; A101-D105 WeakPolarHBondContact O-CB 3.33Å; A101-D105 PolarHBondContact O-N 2.83Å; A101-A138 HydrophobicContact CB-CB 3.87Å; A101-W148 HydrophobicContact CB-CH2 4.45Å; A101-W148 HydrophobicContact CB-CZ3 3.95Å
102	A	98.5	Very high	97.6	Very high	0 Å²	0	20.2 Å²	20.2	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-65.5	-38.3	175.9	0	0	0	0	0	111.9	L15 L16 R19 G98 F99 F100 F106	L15-A102 HydrophobicContact CB-CB 4.36Å; L16-A102 HydrophobicContact CB-CB 4.35Å; L16-A102 HydrophobicContact CD1-CB 4.24Å; R19-A102 HydrophobicContact CB-CB 4.09Å; R19-A102 HydrophobicContact CG-CB 3.96Å; G98-A102 PolarHBondContact O-N 3.42Å; F99-A102 PolarHBondContact O-N 3.43Å; F100-A102 VanDerWaalsContact C-N 3.34Å; F100-A102 PolarHBondContact O-N 3.28Å; A102-F106 WeakPolarHBondContact O-CB 3.19Å; A102-F106 PolarHBondContact O-N 2.79Å; A102-F106 VanDerWaalsContact O-N 3.12Å
103	I	98.5	Very high	97.5	Very high	35 Å²	35	22.6 Å²	22.6	18%	0.179	11%	0.106	C	C	.	.	H	α-helix	trans	-62	-49	171.8	-64.2	170.6	0	0	0	109.6	F12 F99 F100 A101 D105 F106 H107 I153	F12-I103 HydrophobicContact CE2-CG1 3.92Å; F12-I103 HydrophobicContact CZ-CG1 4.04Å; F99-I103 HydrophobicContact CD1-CD1 4Å; F99-I103 HydrophobicContact CE1-CD1 3.44Å; F99-I103 VanDerWaalsContact CE1-CD1 3.44Å; F99-I103 HydrophobicContact CE2-CD1 4.37Å; F99-I103 HydrophobicContact CZ-CD1 3.66Å; F99-I103 PolarHBondContact O-N 2.73Å; F100-I103 HydrophobicContact CD1-CD1 4.48Å; F100-I103 WeakPolarHBondContact O-CB 3.26Å; F100-I103 PolarHBondContact O-N 2.92Å; A101-I103 VanDerWaalsContact C-N 3.33Å; A101-I103 PolarHBondContact O-N 3.16Å; I103-D105 PolarHBondContact O-N 3.29Å; I103-F106 PolarHBondContact O-N 2.79Å; I103-H107 PolarHBondContact O-CD2 3.39Å; I103-H107 VanDerWaalsContact O-CD2 3.22Å; I103-H107 PolarHBondContact O-N 3.39Å; I103-I153 HydrophobicContact CG2-CD1 3.8Å; I103-I153 HydrophobicContact CG2-CG1 4.33Å
104	A	98.6	Very high	97.1	Very high	0 Å²	0	25.2 Å²	25.2	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-58.2	-48.7	178.7	0	0	0	0	0	111.9	F100 A101 F106 H107 L108 W148 C149 I152	F100-A104 PolarHBondContact O-N 3.16Å; A101-A104 PolarHBondContact O-N 3.45Å; A104-F106 VanDerWaalsContact C-N 3.29Å; A104-F106 PolarHBondContact O-N 3.33Å; A104-H107 CarbonylContact O-C 3.2Å; A104-H107 WeakPolarHBondContact O-CA 3.43Å; A104-H107 PolarHBondContact O-N 3.33Å; A104-L108 PolarHBondContact O-N 2.87Å; A104-W148 HydrophobicContact CB-CZ3 4.2Å; A104-C149 HydrophobicContact CB-CB 3.94Å; A104-I152 HydrophobicContact CB-CB 4.32Å; A104-I152 HydrophobicContact CB-CD1 4.17Å; A104-I152 HydrophobicContact CB-CG2 4.46Å; A104-I152 WeakPolarHBondContact O-CG2 3.43Å
105	D	98.6	Very high	96.7	Very high	0 Å²	0	24.5 Å²	24.5	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-54.6	-44.4	176.6	-71.3	-20.5	0	0	0	112.1	L15 R19 A101 I103 L108 Y109 L125 H128	L15-D105 HydrophobicContact CD1-CB 3.94Å; L15-D105 HydrophobicContact CD2-CB 4Å; L15-D105 HydrophobicContact CG-CB 4.45Å; R19-D105 IonicContact CZ-OD1 3.43Å; R19-D105 IonicContact CZ-OD2 3.31Å; R19-D105 VanDerWaalsContact CZ-OD2 3.24Å; R19-D105 IonicContact NE-OD1 3.25Å; R19-D105 IonicContact NE-OD2 3.68Å; R19-D105 PolarHBondContact NE-OD2 3.01Å; R19-D105 VanDerWaalsContact NH2-CG 3.27Å; R19-D105 IonicContact NH2-OD1 2.62Å; R19-D105 PolarHBondContact NH2-OD1 3.41Å; R19-D105 IonicContact NH2-OD2 2.68Å; R19-D105 PolarHBondContact NH2-OD2 3.39Å; A101-D105 WeakPolarHBondContact O-CB 3.33Å; A101-D105 PolarHBondContact O-N 2.83Å; I103-D105 PolarHBondContact O-N 3.29Å; D105-L108 WeakPolarHBondContact O-CB 3.44Å; D105-L108 PolarHBondContact O-N 3.03Å; D105-Y109 PolarHBondContact O-N 3.41Å; D105-L125 HydrophobicContact CB-CD1 4.01Å; D105-L125 WeakPolarHBondContact O-CD1 3.43Å; D105-H128 IonicContact OD1-CD2 2.7Å; D105-H128 PolarHBondContact OD1-CD2 2.96Å; D105-H128 IonicContact OD1-NE2 3.73Å; D105-H128 PolarHBondContact OD1-NE2 2.94Å
106	F	98.3	Very high	96.4	Very high	21 Å²	21	22.5 Å²	22.5	9%	0.092	11%	0.105	C	C	.	.	H	α-helix	trans	-67.1	-37.9	178.2	-179.3	-123.5	0	0	0	112.3	S8 L11 F12 L15 A102 I103 A104 Y109 K110	S8-F106 WeakPolarHBondContact O-CE2 3.26Å; L11-F106 HydrophobicContact CD2-CD2 4.21Å; L11-F106 HydrophobicContact CD2-CE2 4.4Å; L11-F106 HydrophobicContact CG-CD2 4.43Å; F12-F106 HydrophobicContact CB-CD2 4.32Å; F12-F106 HydrophobicContact CB-CE2 4.38Å; F12-F106 HydrophobicContact CB-CG 4.42Å; F12-F106 HydrophobicContact CB-CZ 4.48Å; F12-F106 HydrophobicContact CD2-CB 3.92Å; F12-F106 AromaticContact CD2-CD1 3.99Å; F12-F106 HydrophobicContact CD2-CD1 3.99Å; F12-F106 AromaticContact CD2-CG 3.97Å; F12-F106 HydrophobicContact CD2-CG 3.97Å; L15-F106 HydrophobicContact CD1-CB 3.89Å; A102-F106 WeakPolarHBondContact O-CB 3.19Å; A102-F106 PolarHBondContact O-N 2.79Å; A102-F106 VanDerWaalsContact O-N 3.12Å; I103-F106 PolarHBondContact O-N 2.79Å; A104-F106 VanDerWaalsContact C-N 3.29Å; A104-F106 PolarHBondContact O-N 3.33Å; F106-Y109 PolarHBondContact O-N 2.87Å; F106-K110 HydrophobicContact CD1-CD 4.44Å; F106-K110 HydrophobicContact CE1-CD 4.17Å; F106-K110 HydrophobicContact CZ-CD 4.37Å; F106-K110 WeakPolarHBondContact O-CG 3.38Å; F106-K110 PolarHBondContact O-N 3.42Å
107	H	98.1	Very high	96	Very high	21 Å²	21	21.4 Å²	21.4	10%	0.097	10%	0.099	C	C	.	.	H	α-helix	trans	-68.1	-34.2	173.3	-85.4	-93.4	0	0	0	112.5	I103 A104 K110 L111 I152 I153 S156 Y157	I103-H107 PolarHBondContact O-CD2 3.39Å; I103-H107 VanDerWaalsContact O-CD2 3.22Å; I103-H107 PolarHBondContact O-N 3.39Å; A104-H107 CarbonylContact O-C 3.2Å; A104-H107 WeakPolarHBondContact O-CA 3.43Å; A104-H107 PolarHBondContact O-N 3.33Å; H107-K110 PolarHBondContact O-N 2.96Å; H107-L111 VanDerWaalsContact O-CB 3.25Å; H107-L111 WeakPolarHBondContact O-CB 3.44Å; H107-L111 PolarHBondContact O-N 2.94Å; H107-I152 HydrophobicContact CB-CG2 4.29Å; H107-I153 HydrophobicContact CB-CG1 4.06Å; H107-S156 PolarHBondContact ND1-OG 2.59Å; H107-Y157 AromaticContact CE1-CE2 3.59Å; H107-Y157 AromaticContact CE1-CZ 3.87Å
108	L	98.5	Very high	95.8	Very high	3 Å²	3	22.6 Å²	22.6	2%	0.016	11%	0.105	C	C	.	.	H	α-helix	trans	-61.4	-48.2	171.2	-177.7	62.4	0	0	0	110.3	A104 D105 K110 L111 I112 T124 H128 I152 P388	A104-L108 PolarHBondContact O-N 2.87Å; D105-L108 WeakPolarHBondContact O-CB 3.44Å; D105-L108 PolarHBondContact O-N 3.03Å; L108-K110 VanDerWaalsContact C-N 3.34Å; L108-K110 PolarHBondContact O-N 2.75Å; L108-L111 WeakPolarHBondContact O-CB 3.17Å; L108-L111 PolarHBondContact O-N 2.94Å; L108-I112 HydrophobicContact CD1-CD1 4.28Å; L108-I112 HydrophobicContact CD1-CG1 4.01Å; L108-I112 HydrophobicContact CG-CG1 4.38Å; L108-I112 WeakPolarHBondContact O-CG1 3.23Å; L108-I112 PolarHBondContact O-N 3.08Å; L108-T124 HydrophobicContact CD2-CG2 4.19Å; L108-T124 HydrophobicContact CG-CG2 4.34Å; L108-H128 HydrophobicContact CD2-CB 3.7Å; L108-H128 WeakPolarHBondContact CD2-CD2 3.15Å; L108-I152 HydrophobicContact CB-CG2 3.68Å; L108-I152 HydrophobicContact CD1-CG2 4.46Å; L108-P388 HydrophobicContact CD1-CB 3.95Å; L108-P388 HydrophobicContact CD2-CB 4.31Å
109	Y	97.9	Very high	95.5	Very high	11 Å²	11	25.1 Å²	25.1	4%	0.043	12%	0.116	C	C	.	.	H	α-helix	trans	-56.2	-47.7	176.5	172.7	-102.4	0	0	0	111.9	F5 L11 D105 F106 L111 I112 N113 F118 A121 L125	F5-Y109 HydrophobicContact CD1-CD2 4.29Å; F5-Y109 AromaticContact CD1-CE2 3.86Å; F5-Y109 HydrophobicContact CD1-CE2 3.86Å; F5-Y109 PolarHBondContact O-OH 3.42Å; L11-Y109 HydrophobicContact CD2-CD1 3.39Å; L11-Y109 HydrophobicContact CD2-CD2 4.16Å; L11-Y109 HydrophobicContact CD2-CE1 3.57Å; L11-Y109 HydrophobicContact CD2-CE2 4.33Å; L11-Y109 HydrophobicContact CD2-CG 3.69Å; D105-Y109 PolarHBondContact O-N 3.41Å; F106-Y109 PolarHBondContact O-N 2.87Å; Y109-L111 PolarHBondContact O-N 3.09Å; Y109-I112 PolarHBondContact O-N 3.48Å; Y109-N113 VanDerWaalsContact O-CB 3.24Å; Y109-N113 WeakPolarHBondContact O-CB 3.41Å; Y109-N113 PolarHBondContact O-N 3.33Å; Y109-F118 WeakPolarHBondContact OH-CD2 3.17Å; Y109-F118 WeakPolarHBondContact OH-CE2 3.2Å; Y109-A121 HydrophobicContact CD2-CB 3.65Å; Y109-A121 HydrophobicContact CE2-CB 3.63Å; Y109-L125 HydrophobicContact CD2-CD2 4.37Å; Y109-L125 HydrophobicContact CG-CD2 4.49Å
110	K	95.2	Very high	95.4	Very high	88 Å²	88	20.9 Å²	20.9	38%	0.383	10%	0.098	S	C	.	.	H	α-helix	trans	-60.6	-45.6	176.6	-75.5	177.8	173.2	173.5	0	112.8	F106 H107 L108 N113 Q114	F106-K110 HydrophobicContact CD1-CD 4.44Å; F106-K110 HydrophobicContact CE1-CD 4.17Å; F106-K110 HydrophobicContact CZ-CD 4.37Å; F106-K110 WeakPolarHBondContact O-CG 3.38Å; F106-K110 PolarHBondContact O-N 3.42Å; H107-K110 PolarHBondContact O-N 2.96Å; L108-K110 VanDerWaalsContact C-N 3.34Å; L108-K110 PolarHBondContact O-N 2.75Å; K110-N113 PolarHBondContact O-N 3.32Å; K110-Q114 PolarHBondContact O-N 2.95Å
111	L	95.2	Very high	95.3	Very high	6 Å²	6	18.3 Å²	18.3	3%	0.031	9%	0.086	C	C	.	.	H	α-helix	trans	-56.6	-53.2	177.8	168.6	57.6	0	0	0	110.4	H107 L108 Y109 N113 Q114 L115 L155 W160	H107-L111 VanDerWaalsContact O-CB 3.25Å; H107-L111 WeakPolarHBondContact O-CB 3.44Å; H107-L111 PolarHBondContact O-N 2.94Å; L108-L111 WeakPolarHBondContact O-CB 3.17Å; L108-L111 PolarHBondContact O-N 2.94Å; Y109-L111 PolarHBondContact O-N 3.09Å; L111-N113 VanDerWaalsContact C-N 3.33Å; L111-N113 PolarHBondContact O-N 2.91Å; L111-Q114 WeakPolarHBondContact O-CB 3.5Å; L111-Q114 PolarHBondContact O-N 3.42Å; L111-L115 HydrophobicContact CD1-CD1 3.73Å; L111-L115 HydrophobicContact CD1-CG 3.96Å; L111-L115 HydrophobicContact CG-CD1 4.18Å; L111-L115 WeakPolarHBondContact O-CG 3.47Å; L111-L115 PolarHBondContact O-N 3.27Å; L111-L155 WeakPolarHBondContact CD1-O 3.45Å; L111-L155 HydrophobicContact CD2-CB 3.75Å; L111-W160 HydrophobicContact CD1-CZ2 4.22Å
112	I	95.6	Very high	95.1	Very high	3 Å²	3	19.4 Å²	19.4	2%	0.015	9%	0.091	C	C	.	.	H	α-helix	trans	-68.9	-35.6	-177	-58.5	-47.9	0	0	0	111.8	L108 Y109 Q114 L115 S116 G117 I120 A121 T124 Y392	L108-I112 HydrophobicContact CD1-CD1 4.28Å; L108-I112 HydrophobicContact CD1-CG1 4.01Å; L108-I112 HydrophobicContact CG-CG1 4.38Å; L108-I112 WeakPolarHBondContact O-CG1 3.23Å; L108-I112 PolarHBondContact O-N 3.08Å; Y109-I112 PolarHBondContact O-N 3.48Å; I112-Q114 VanDerWaalsContact C-N 3.28Å; I112-Q114 PolarHBondContact O-N 3.25Å; I112-L115 HydrophobicContact CD1-CD1 4.38Å; I112-L115 PolarHBondContact O-N 3.25Å; I112-L115 VanDerWaalsContact O-N 3.13Å; I112-S116 PolarHBondContact O-N 3.09Å; I112-G117 PolarHBondContact O-N 3.28Å; I112-I120 HydrophobicContact CG2-CB 4.42Å; I112-I120 HydrophobicContact CG2-CG2 3.77Å; I112-A121 HydrophobicContact CB-CB 4.11Å; I112-A121 HydrophobicContact CG2-CB 4.06Å; I112-T124 HydrophobicContact CG1-CG2 3.8Å; I112-Y392 HydrophobicContact CD1-CD1 4.09Å; I112-Y392 HydrophobicContact CD1-CD2 3.52Å; I112-Y392 HydrophobicContact CD1-CE2 4.03Å; I112-Y392 HydrophobicContact CD1-CG 3.54Å; I112-Y392 HydrophobicContact CG1-CD2 4.16Å; I112-Y392 HydrophobicContact CG1-CG 4.49Å; I112-Y392 HydrophobicContact CG2-CD2 3.7Å; I112-Y392 HydrophobicContact CG2-CE2 3.8Å
113	N	93.4	Very high	95	Very high	58 Å²	58	23.4 Å²	23.4	31%	0.31	11%	0.106	S	C	.	.	H	α-helix	trans	-60.7	-40.9	174.5	-171.1	58.8	0	0	0	111	Y109 K110 L111 G117 F118 A121	Y109-N113 VanDerWaalsContact O-CB 3.24Å; Y109-N113 WeakPolarHBondContact O-CB 3.41Å; Y109-N113 PolarHBondContact O-N 3.33Å; K110-N113 PolarHBondContact O-N 3.32Å; L111-N113 VanDerWaalsContact C-N 3.33Å; L111-N113 PolarHBondContact O-N 2.91Å; N113-G117 VanDerWaalsContact O-CA 3.25Å; N113-G117 WeakPolarHBondContact O-CA 3.37Å; N113-G117 PolarHBondContact O-N 3.23Å; N113-F118 WeakPolarHBondContact OD1-CA 3.31Å; N113-F118 PolarHBondContact OD1-N 3.05Å; N113-F118 VanDerWaalsContact OD1-N 3.09Å; N113-A121 HydrophobicContact CB-CB 3.79Å
114	Q	88.4	Confident	95	Very high	55 Å²	55	21.7 Å²	21.7	26%	0.257	10%	0.098	S	C	.	.	H	α-helix	trans	-65.2	-40.5	173.3	179.8	-178.5	-22.5	0	0	112.4	K110 L111 I112 N161	K110-Q114 PolarHBondContact O-N 2.95Å; L111-Q114 WeakPolarHBondContact O-CB 3.5Å; L111-Q114 PolarHBondContact O-N 3.42Å; I112-Q114 VanDerWaalsContact C-N 3.28Å; I112-Q114 PolarHBondContact O-N 3.25Å; Q114-N161 PolarHBondContact NE2-OD1 2.84Å
115	L	89.5	Confident	95	Very high	1 Å²	1	22 Å²	22	1%	0.005	10%	0.099	C	C	.	.	H	α-helix	trans	-77.8	-37	-173.9	-71.3	-175.6	0	0	0	114.2	L111 I112 W160 P357 Y392	L111-L115 HydrophobicContact CD1-CD1 3.73Å; L111-L115 HydrophobicContact CD1-CG 3.96Å; L111-L115 HydrophobicContact CG-CD1 4.18Å; L111-L115 WeakPolarHBondContact O-CG 3.47Å; L111-L115 PolarHBondContact O-N 3.27Å; I112-L115 HydrophobicContact CD1-CD1 4.38Å; I112-L115 PolarHBondContact O-N 3.25Å; I112-L115 VanDerWaalsContact O-N 3.13Å; L115-W160 HydrophobicContact CD1-CD2 4.29Å; L115-W160 HydrophobicContact CD1-CE3 4.47Å; L115-W160 HydrophobicContact CD1-CZ2 4.45Å; L115-W160 HydrophobicContact CD2-CB 3.62Å; L115-W160 HydrophobicContact CD2-CD2 3.7Å; L115-W160 HydrophobicContact CD2-CE3 4Å; L115-W160 HydrophobicContact CD2-CG 3.53Å; L115-P357 HydrophobicContact CD1-CB 4.28Å; L115-P357 HydrophobicContact CD2-CB 3.8Å; L115-P357 HydrophobicContact CD2-CG 4.02Å; L115-P357 HydrophobicContact CG-CB 4.47Å; L115-Y392 HydrophobicContact CD1-CE1 4.36Å
116	S	90.2	Very high	95	Very high	1 Å²	1	26.5 Å²	26.5	1%	0.007	12%	0.119	C	C	.	.	H	α-helix	trans	-149.5	5.2	-169.1	-68.3	0	0	0	0	114.7	I112 T337 R340 Y392	I112-S116 PolarHBondContact O-N 3.09Å; S116-T337 PolarHBondContact O-OG1 3.41Å; S116-R340 PolarHBondContact OG-NE 3.31Å; S116-R340 VanDerWaalsContact OG-NE 3.14Å; S116-Y392 PolarHBondContact OG-OH 3.35Å
117	G	90.5	Very high	95	Very high	1 Å²	1	26.2 Å²	26.2	1%	0.01	12%	0.118	C	C	.	.			trans	95.4	177.3	168.2	0	0	0	0	0	116.2	I112 N113 E119 I120 A121 E339	I112-G117 PolarHBondContact O-N 3.28Å; N113-G117 VanDerWaalsContact O-CA 3.25Å; N113-G117 WeakPolarHBondContact O-CA 3.37Å; N113-G117 PolarHBondContact O-N 3.23Å; G117-E119 PolarHBondContact O-N 2.96Å; G117-I120 PolarHBondContact O-N 2.81Å; G117-A121 WeakPolarHBondContact O-CB 3.23Å; G117-A121 PolarHBondContact O-N 3.05Å; G117-E339 WeakPolarHBondContact CA-OE2 3.41Å
118	F	92.7	Very high	95	Very high	27 Å²	27	25.2 Å²	25.2	12%	0.118	11%	0.113	C	C	.	.	H	α-helix	trans	-62.3	-46.9	-167	176	-110.3	0	0	0	113.2	F5 R6 Y109 N113 I120 A121 K122 E339	F5-F118 HydrophobicContact CB-CE2 3.68Å; F5-F118 HydrophobicContact CB-CZ 3.83Å; R6-F118 HydrophobicContact CG-CE1 4.38Å; R6-F118 HydrophobicContact CG-CE2 3.83Å; R6-F118 HydrophobicContact CG-CZ 3.59Å; Y109-F118 WeakPolarHBondContact OH-CD2 3.17Å; Y109-F118 WeakPolarHBondContact OH-CE2 3.2Å; N113-F118 WeakPolarHBondContact OD1-CA 3.31Å; N113-F118 PolarHBondContact OD1-N 3.05Å; N113-F118 VanDerWaalsContact OD1-N 3.09Å; F118-I120 PolarHBondContact O-N 2.9Å; F118-A121 PolarHBondContact O-N 2.79Å; F118-K122 HydrophobicContact CD1-CD 4.25Å; F118-K122 HydrophobicContact CD2-CG 4.5Å; F118-K122 HydrophobicContact CE1-CD 3.61Å; F118-K122 HydrophobicContact CE1-CG 4.34Å; F118-K122 HydrophobicContact CE2-CD 4.13Å; F118-K122 HydrophobicContact CE2-CG 4.15Å; F118-K122 HydrophobicContact CZ-CD 3.53Å; F118-K122 HydrophobicContact CZ-CG 4.06Å; F118-K122 WeakPolarHBondContact O-CG 3.26Å; F118-K122 PolarHBondContact O-N 3.36Å; F118-E339 PolarHBondContact N-OE2 2.85Å
119	E	92.9	Very high	94.9	Very high	53 Å²	53	26.1 Å²	26.1	25%	0.248	12%	0.119	C	C	.	.	H	α-helix	trans	-62	-45.7	-177.6	-67.8	-53.5	130.6	0	0	112.2	G117 A121 K122 W123 T337 V399	G117-E119 PolarHBondContact O-N 2.96Å; E119-A121 VanDerWaalsContact C-N 3.32Å; E119-A121 PolarHBondContact O-N 3.31Å; E119-K122 VanDerWaalsContact CD-CE 3.45Å; E119-K122 PolarHBondContact O-N 2.91Å; E119-K122 VanDerWaalsContact OE1-CE 3.27Å; E119-K122 WeakPolarHBondContact OE1-CE 3.32Å; E119-K122 IonicContact OE1-NZ 3.24Å; E119-K122 PolarHBondContact OE1-NZ 3.06Å; E119-K122 WeakPolarHBondContact OE2-CE 3.4Å; E119-K122 IonicContact OE2-NZ 3.32Å; E119-K122 PolarHBondContact OE2-NZ 3.4Å; E119-W123 VanDerWaalsContact O-CD1 3.29Å; E119-W123 PolarHBondContact O-N 2.99Å; E119-T337 HydrophobicContact CB-CG2 4.28Å; E119-V399 HydrophobicContact CB-CG2 4.14Å
120	I	95.1	Very high	94.9	Very high	0 Å²	0	28.4 Å²	28.4	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-69.7	-34.7	-179.3	-65.6	170.2	0	0	0	110.3	I112 G117 F118 W123 T124 L336 Y392 I396 V399	I112-I120 HydrophobicContact CG2-CB 4.42Å; I112-I120 HydrophobicContact CG2-CG2 3.77Å; G117-I120 PolarHBondContact O-N 2.81Å; F118-I120 PolarHBondContact O-N 2.9Å; I120-W123 PolarHBondContact O-N 2.92Å; I120-T124 VanDerWaalsContact O-CB 3.29Å; I120-T124 WeakPolarHBondContact O-CB 3.35Å; I120-T124 PolarHBondContact O-N 3.4Å; I120-T124 PolarHBondContact O-OG1 3.22Å; I120-L336 HydrophobicContact CD1-CB 4.39Å; I120-Y392 HydrophobicContact CG2-CD2 4.04Å; I120-Y392 HydrophobicContact CG2-CE2 3.83Å; I120-I396 HydrophobicContact CD1-CG1 4.24Å; I120-I396 HydrophobicContact CG2-CG1 3.69Å; I120-V399 HydrophobicContact CB-CG2 4.47Å; I120-V399 HydrophobicContact CG1-CB 4.12Å; I120-V399 HydrophobicContact CG1-CG1 4.35Å; I120-V399 HydrophobicContact CG1-CG2 3.75Å
121	A	96.3	Very high	95	Very high	0 Å²	0	24.2 Å²	24.2	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-63.7	-43.6	175.9	0	0	0	0	0	112.6	Y109 I112 N113 G117 F118 E119 T124 L125	Y109-A121 HydrophobicContact CD2-CB 3.65Å; Y109-A121 HydrophobicContact CE2-CB 3.63Å; I112-A121 HydrophobicContact CB-CB 4.11Å; I112-A121 HydrophobicContact CG2-CB 4.06Å; N113-A121 HydrophobicContact CB-CB 3.79Å; G117-A121 WeakPolarHBondContact O-CB 3.23Å; G117-A121 PolarHBondContact O-N 3.05Å; F118-A121 PolarHBondContact O-N 2.79Å; E119-A121 VanDerWaalsContact C-N 3.32Å; E119-A121 PolarHBondContact O-N 3.31Å; A121-T124 PolarHBondContact O-N 3.04Å; A121-L125 WeakPolarHBondContact O-CB 3.16Å; A121-L125 PolarHBondContact O-N 2.78Å
122	K	95.9	Very high	95.1	Very high	24 Å²	24	28.9 Å²	28.9	10%	0.104	14%	0.135	C	C	.	.	H	α-helix	trans	-56.9	-52.5	175	-72.6	-171.9	-72.6	177.2	0	111.5	E2 F5 F118 E119 L125 F126	E2-K122 IonicContact OE1-NZ 3.52Å; E2-K122 PolarHBondContact OE1-NZ 3.42Å; F5-K122 HydrophobicContact CB-CD 4.08Å; F5-K122 HydrophobicContact CB-CG 3.93Å; F5-K122 HydrophobicContact CD1-CB 4.26Å; F5-K122 HydrophobicContact CD1-CD 4.46Å; F5-K122 HydrophobicContact CD1-CG 3.64Å; F5-K122 HydrophobicContact CD2-CD 4.02Å; F5-K122 HydrophobicContact CD2-CG 4.08Å; F5-K122 HydrophobicContact CE1-CB 4.16Å; F5-K122 HydrophobicContact CE1-CG 4.05Å; F5-K122 HydrophobicContact CE2-CG 4.49Å; F5-K122 HydrophobicContact CG-CD 3.96Å; F5-K122 HydrophobicContact CG-CG 3.64Å; F5-K122 HydrophobicContact CZ-CB 4.45Å; F5-K122 HydrophobicContact CZ-CG 4.47Å; F118-K122 HydrophobicContact CD1-CD 4.25Å; F118-K122 HydrophobicContact CD2-CG 4.5Å; F118-K122 HydrophobicContact CE1-CD 3.61Å; F118-K122 HydrophobicContact CE1-CG 4.34Å; F118-K122 HydrophobicContact CE2-CD 4.13Å; F118-K122 HydrophobicContact CE2-CG 4.15Å; F118-K122 HydrophobicContact CZ-CD 3.53Å; F118-K122 HydrophobicContact CZ-CG 4.06Å; F118-K122 WeakPolarHBondContact O-CG 3.26Å; F118-K122 PolarHBondContact O-N 3.36Å; E119-K122 VanDerWaalsContact CD-CE 3.45Å; E119-K122 PolarHBondContact O-N 2.91Å; E119-K122 VanDerWaalsContact OE1-CE 3.27Å; E119-K122 WeakPolarHBondContact OE1-CE 3.32Å; E119-K122 IonicContact OE1-NZ 3.24Å; E119-K122 PolarHBondContact OE1-NZ 3.06Å; E119-K122 WeakPolarHBondContact OE2-CE 3.4Å; E119-K122 IonicContact OE2-NZ 3.32Å; E119-K122 PolarHBondContact OE2-NZ 3.4Å; K122-L125 PolarHBondContact O-N 2.79Å; K122-F126 PolarHBondContact O-N 2.88Å
123	W	96.8	Very high	95.1	Very high	83 Å²	83	28.9 Å²	28.9	31%	0.314	14%	0.135	S	C	.	.	H	α-helix	trans	-68.7	-36	-177.9	-77.7	105.8	0	0	0	112.8	E119 I120 F126 H127 V399 V402	E119-W123 VanDerWaalsContact O-CD1 3.29Å; E119-W123 PolarHBondContact O-N 2.99Å; I120-W123 PolarHBondContact O-N 2.92Å; W123-F126 HydrophobicContact CE3-CD1 4.01Å; W123-F126 HydrophobicContact CZ3-CD1 4.06Å; W123-F126 HydrophobicContact CZ3-CE1 4.28Å; W123-F126 PolarHBondContact O-N 2.95Å; W123-H127 PolarHBondContact O-CD2 3.24Å; W123-H127 PolarHBondContact O-N 3.29Å; W123-V399 HydrophobicContact CB-CG2 4.43Å; W123-V399 VanDerWaalsContact CD1-CG2 3.46Å; W123-V399 HydrophobicContact CG-CG2 4.18Å; W123-V402 HydrophobicContact CZ2-CG2 3.95Å
124	T	98.2	Very high	95.3	Very high	0 Å²	0	26.1 Å²	26.1	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-62.4	-47.2	174.1	-59.3	0	0	0	0	111	L108 I112 I120 A121 F126 H127 H128 M391	L108-T124 HydrophobicContact CD2-CG2 4.19Å; L108-T124 HydrophobicContact CG-CG2 4.34Å; I112-T124 HydrophobicContact CG1-CG2 3.8Å; I120-T124 VanDerWaalsContact O-CB 3.29Å; I120-T124 WeakPolarHBondContact O-CB 3.35Å; I120-T124 PolarHBondContact O-N 3.4Å; I120-T124 PolarHBondContact O-OG1 3.22Å; A121-T124 PolarHBondContact O-N 3.04Å; T124-F126 VanDerWaalsContact C-N 3.33Å; T124-F126 PolarHBondContact O-N 3.2Å; T124-H127 PolarHBondContact O-N 2.98Å; T124-H128 VanDerWaalsContact O-CB 3.27Å; T124-H128 WeakPolarHBondContact O-CB 3.41Å; T124-H128 PolarHBondContact O-N 3.27Å; T124-M391 HydrophobicContact CG2-CB 4.2Å
125	L	98.2	Very high	95.7	Very high	5 Å²	5	26.2 Å²	26.2	3%	0.026	12%	0.122	C	C	.	.	H	α-helix	trans	-61.4	-43.7	178	-175.9	63.7	0	0	0	111.1	F5 L11 L15 D105 Y109 A121 K122 H127 H128 V129	F5-L125 HydrophobicContact CD1-CD2 4.42Å; F5-L125 HydrophobicContact CE1-CB 4.48Å; F5-L125 HydrophobicContact CE1-CD2 3.76Å; L11-L125 HydrophobicContact CD1-CD2 3.89Å; L11-L125 HydrophobicContact CD2-CD2 4.32Å; L15-L125 HydrophobicContact CD1-CD2 4.31Å; L15-L125 HydrophobicContact CD2-CD1 4.23Å; L15-L125 HydrophobicContact CD2-CD2 4.19Å; D105-L125 HydrophobicContact CB-CD1 4.01Å; D105-L125 WeakPolarHBondContact O-CD1 3.43Å; Y109-L125 HydrophobicContact CD2-CD2 4.37Å; Y109-L125 HydrophobicContact CG-CD2 4.49Å; A121-L125 WeakPolarHBondContact O-CB 3.16Å; A121-L125 PolarHBondContact O-N 2.78Å; K122-L125 PolarHBondContact O-N 2.79Å; L125-H127 PolarHBondContact O-N 2.88Å; L125-H128 WeakPolarHBondContact O-CB 3.22Å; L125-H128 PolarHBondContact O-N 3.29Å; L125-H128 VanDerWaalsContact O-N 3.15Å; L125-V129 HydrophobicContact CD1-CG1 3.93Å; L125-V129 HydrophobicContact CG-CG1 4.3Å; L125-V129 WeakPolarHBondContact O-CG2 3.39Å; L125-V129 PolarHBondContact O-N 3.3Å
126	F	97.4	Very high	96	Very high	96 Å²	96	28.8 Å²	28.8	42%	0.421	13%	0.132	S	C	.	.	H	α-helix	trans	-54.9	-53.1	175.3	173.5	-99.5	0	0	0	111.8	K122 W123 T124 H128 V129 C130	K122-F126 PolarHBondContact O-N 2.88Å; W123-F126 HydrophobicContact CE3-CD1 4.01Å; W123-F126 HydrophobicContact CZ3-CD1 4.06Å; W123-F126 HydrophobicContact CZ3-CE1 4.28Å; W123-F126 PolarHBondContact O-N 2.95Å; T124-F126 VanDerWaalsContact C-N 3.33Å; T124-F126 PolarHBondContact O-N 3.2Å; F126-H128 PolarHBondContact O-N 3.16Å; F126-V129 WeakPolarHBondContact O-CG2 3.43Å; F126-V129 PolarHBondContact O-N 2.89Å; F126-C130 VanDerWaalsContact O-CB 3.23Å; F126-C130 WeakPolarHBondContact O-CB 3.34Å; F126-C130 PolarHBondContact O-N 3.32Å; F126-C130 PolarHBondContact O-SG 3.4Å; F126-C130 VanDerWaalsContact O-SG 3.37Å
127	H	98.3	Very high	96.3	Very high	14 Å²	14	28.8 Å²	28.8	7%	0.065	13%	0.132	C	C	.	.	H	α-helix	trans	-60.1	-38.1	177	-75.8	-61.3	0	0	0	112.3	W123 T124 L125 N131 Q314 L317 M391 S398	W123-H127 PolarHBondContact O-CD2 3.24Å; W123-H127 PolarHBondContact O-N 3.29Å; T124-H127 PolarHBondContact O-N 2.98Å; L125-H127 PolarHBondContact O-N 2.88Å; H127-N131 WeakPolarHBondContact O-CB 3.36Å; H127-N131 PolarHBondContact O-N 2.96Å; H127-Q314 HydrophobicContact CB-CG 4.36Å; H127-L317 WeakPolarHBondContact CE1-CD1 3.3Å; H127-M391 VanDerWaalsContact C-SD 3.58Å; H127-M391 HydrophobicContact CB-CB 4.5Å; H127-M391 HydrophobicContact CB-SD 3.76Å; H127-M391 VanDerWaalsContact O-SD 3.4Å; H127-S398 PolarHBondContact NE2-OG 3.45Å
128	H	98.1	Very high	96.6	Very high	0 Å²	0	28.8 Å²	28.8	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-66.9	-46.3	-178.6	-169	68.3	0	0	0	113.3	D105 L108 T124 L125 F126 C130 T134 W148 M391	D105-H128 IonicContact OD1-CD2 2.7Å; D105-H128 PolarHBondContact OD1-CD2 2.96Å; D105-H128 IonicContact OD1-NE2 3.73Å; D105-H128 PolarHBondContact OD1-NE2 2.94Å; L108-H128 HydrophobicContact CD2-CB 3.7Å; L108-H128 WeakPolarHBondContact CD2-CD2 3.15Å; T124-H128 VanDerWaalsContact O-CB 3.27Å; T124-H128 WeakPolarHBondContact O-CB 3.41Å; T124-H128 PolarHBondContact O-N 3.27Å; L125-H128 WeakPolarHBondContact O-CB 3.22Å; L125-H128 PolarHBondContact O-N 3.29Å; L125-H128 VanDerWaalsContact O-N 3.15Å; F126-H128 PolarHBondContact O-N 3.16Å; H128-C130 VanDerWaalsContact C-N 3.35Å; H128-T134 WeakPolarHBondContact O-CB 3.32Å; H128-T134 WeakPolarHBondContact O-CG2 3.29Å; H128-W148 AromaticContact CE1-CE2 3.97Å; H128-W148 AromaticContact CE1-CZ2 3.37Å; H128-W148 WeakPolarHBondContact CE1-CZ2 3.45Å; H128-W148 AromaticContact NE2-CH2 3.78Å; H128-W148 AromaticContact NE2-CZ2 3.17Å; H128-W148 WeakPolarHBondContact NE2-CZ2 3.43Å; H128-M391 HydrophobicContact CB-CB 4.11Å; H128-M391 HydrophobicContact CB-CG 4.03Å
129	V	97.2	Very high	96.7	Very high	23 Å²	23	27.5 Å²	27.5	14%	0.139	13%	0.126	C	C	.	.	H	α-helix	trans	-76.2	-23.6	179.1	-57.8	0	0	0	0	112.6	L15 F18 L125 F126 I135	L15-V129 HydrophobicContact CD2-CG1 4.07Å; F18-V129 HydrophobicContact CE1-CB 3.85Å; F18-V129 HydrophobicContact CE1-CG1 4.3Å; F18-V129 HydrophobicContact CZ-CB 4.22Å; L125-V129 HydrophobicContact CD1-CG1 3.93Å; L125-V129 HydrophobicContact CG-CG1 4.3Å; L125-V129 WeakPolarHBondContact O-CG2 3.39Å; L125-V129 PolarHBondContact O-N 3.3Å; F126-V129 WeakPolarHBondContact O-CG2 3.43Å; F126-V129 PolarHBondContact O-N 2.89Å; V129-I135 VanDerWaalsContact O-CD1 3.27Å; V129-I135 WeakPolarHBondContact O-CD1 3.34Å; V129-I135 WeakPolarHBondContact O-CG1 3.44Å
130	C	96.8	Very high	96.9	Very high	59 Å²	59	25 Å²	25	40%	0.399	11%	0.114	S	C	.	.	H	α-helix	trans	-90.8	-9.9	175.9	-67.8	0	0	0	0	113.9	F126 H128 W132	F126-C130 VanDerWaalsContact O-CB 3.23Å; F126-C130 WeakPolarHBondContact O-CB 3.34Å; F126-C130 PolarHBondContact O-N 3.32Å; F126-C130 PolarHBondContact O-SG 3.4Å; F126-C130 VanDerWaalsContact O-SG 3.37Å; H128-C130 VanDerWaalsContact C-N 3.35Å; C130-W132 PolarHBondContact O-N 2.99Å
131	N	98	Very high	96.9	Very high	0 Å²	0	25 Å²	25	0%	0	11%	0.114	C	C	.	.			trans	-66.2	124.1	176	174.6	-97.7	0	0	0	109.8	H127 F133 T134 I135 M310 Q314 M391	H127-N131 WeakPolarHBondContact O-CB 3.36Å; H127-N131 PolarHBondContact O-N 2.96Å; N131-F133 VanDerWaalsContact C-N 3.29Å; N131-F133 PolarHBondContact O-N 3.44Å; N131-F133 PolarHBondContact OD1-N 3.33Å; N131-T134 PolarHBondContact O-N 3.15Å; N131-T134 PolarHBondContact OD1-N 3.18Å; N131-T134 PolarHBondContact OD1-OG1 3.18Å; N131-I135 WeakPolarHBondContact O-CG1 3.5Å; N131-I135 PolarHBondContact O-N 2.94Å; N131-M310 PolarHBondContact ND2-O 2.8Å; N131-Q314 PolarHBondContact ND2-OE1 3.26Å; N131-M391 HydrophobicContact CB-CE 4.41Å; N131-M391 HydrophobicContact CB-SD 4.05Å
132	W	96.8	Very high	96.9	Very high	104 Å²	104	25 Å²	25	39%	0.394	11%	0.114	S	C	.	.	H	α-helix	trans	-58.5	-40.5	-173	80	-84.4	0	0	0	112.4	C130 I135 Y136 A309 M310 L312	C130-W132 PolarHBondContact O-N 2.99Å; W132-I135 PolarHBondContact O-N 3.44Å; W132-Y136 VanDerWaalsContact O-CB 3.26Å; W132-Y136 WeakPolarHBondContact O-CB 3.34Å; W132-Y136 PolarHBondContact O-N 3.33Å; W132-A309 WeakPolarHBondContact CZ2-O 3.31Å; W132-A309 PolarHBondContact NE1-O 3.12Å; W132-M310 PolarHBondContact NE1-O 3.28Å; W132-L312 HydrophobicContact CG-CD2 4.29Å
133	F	97.1	Very high	97	Very high	2 Å²	2	24.7 Å²	24.7	1%	0.009	12%	0.115	C	C	.	.	H	α-helix	trans	-70.7	-39.1	-178.4	-169.4	-99	0	0	0	111	N131 Y136 C137 M310 F380 F384	N131-F133 VanDerWaalsContact C-N 3.29Å; N131-F133 PolarHBondContact O-N 3.44Å; N131-F133 PolarHBondContact OD1-N 3.33Å; F133-Y136 HydrophobicContact CD2-CD1 4.46Å; F133-Y136 PolarHBondContact O-N 2.98Å; F133-C137 HydrophobicContact CE1-CB 4.24Å; F133-C137 HydrophobicContact CZ-CB 4.48Å; F133-C137 WeakPolarHBondContact CZ-SG 3.31Å; F133-C137 WeakPolarHBondContact O-CB 3.36Å; F133-C137 PolarHBondContact O-N 2.89Å; F133-M310 HydrophobicContact CB-CB 4.34Å; F133-M310 HydrophobicContact CD1-CB 4.37Å; F133-M310 HydrophobicContact CD1-CE 3.68Å; F133-M310 HydrophobicContact CD1-CG 4.13Å; F133-M310 HydrophobicContact CD2-CG 4.15Å; F133-M310 HydrophobicContact CE1-CE 3.46Å; F133-M310 VanDerWaalsContact CE1-CE 3.46Å; F133-M310 HydrophobicContact CE1-CG 4.29Å; F133-M310 HydrophobicContact CE1-SD 4.41Å; F133-M310 HydrophobicContact CE2-CG 4.31Å; F133-M310 HydrophobicContact CG-CB 4.21Å; F133-M310 HydrophobicContact CG-CG 4.05Å; F133-M310 HydrophobicContact CZ-CE 4.15Å; F133-M310 HydrophobicContact CZ-CG 4.37Å; F133-F380 HydrophobicContact CE1-CB 4.44Å; F133-F380 HydrophobicContact CE2-CB 3.64Å; F133-F380 HydrophobicContact CE2-CG 4.29Å; F133-F380 HydrophobicContact CZ-CB 3.48Å; F133-F380 VanDerWaalsContact CZ-CB 3.48Å; F133-F384 AromaticContact CD1-CD2 3.67Å; F133-F384 HydrophobicContact CD1-CD2 3.67Å; F133-F384 AromaticContact CD1-CE2 3.77Å; F133-F384 HydrophobicContact CD1-CE2 3.77Å; F133-F384 HydrophobicContact CE1-CB 4.28Å; F133-F384 AromaticContact CE1-CD2 3.56Å; F133-F384 HydrophobicContact CE1-CD2 3.56Å; F133-F384 HydrophobicContact CE1-CE2 4.03Å; F133-F384 AromaticContact CE1-CG 3.96Å; F133-F384 HydrophobicContact CE1-CG 3.96Å
134	T	97.5	Very high	96.9	Very high	0 Å²	0	20.8 Å²	20.8	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-62.9	-40.8	171.9	-57.1	0	0	0	0	112	R19 H128 N131 Y136 A138 W148	R19-T134 PolarHBondContact NH1-O 3.12Å; H128-T134 WeakPolarHBondContact O-CB 3.32Å; H128-T134 WeakPolarHBondContact O-CG2 3.29Å; N131-T134 PolarHBondContact O-N 3.15Å; N131-T134 PolarHBondContact OD1-N 3.18Å; N131-T134 PolarHBondContact OD1-OG1 3.18Å; T134-Y136 VanDerWaalsContact C-N 3.35Å; T134-A138 HydrophobicContact CG2-CB 4.35Å; T134-A138 WeakPolarHBondContact O-CB 3.49Å; T134-A138 PolarHBondContact O-N 3.01Å; T134-W148 HydrophobicContact CG2-CH2 3.96Å; T134-W148 HydrophobicContact CG2-CZ2 3.58Å
135	I	96.4	Very high	96.9	Very high	58 Å²	58	20.9 Å²	20.9	30%	0.297	10%	0.101	S	C	.	.	H	α-helix	trans	-62	-47	174.5	-66.7	168.3	0	0	0	109.7	F18 N22 V129 N131 W132 P139	F18-I135 HydrophobicContact CZ-CG1 4.38Å; N22-I135 PolarHBondContact ND2-O 3.22Å; N22-I135 PolarHBondContact OD1-O 3.18Å; V129-I135 VanDerWaalsContact O-CD1 3.27Å; V129-I135 WeakPolarHBondContact O-CD1 3.34Å; V129-I135 WeakPolarHBondContact O-CG1 3.44Å; N131-I135 WeakPolarHBondContact O-CG1 3.5Å; N131-I135 PolarHBondContact O-N 2.94Å; W132-I135 PolarHBondContact O-N 3.44Å; I135-P139 VanDerWaalsContact O-CD 3.31Å; I135-P139 WeakPolarHBondContact O-CD 3.38Å
136	Y	95.6	Very high	96.9	Very high	55 Å²	55	21 Å²	21	22%	0.216	10%	0.101	C	C	.	.	H	α-helix	trans	-67.8	-41	-176.4	174.1	-106.8	0	0	0	114.3	S29 Y30 W132 F133 T134 R140	S29-Y136 PolarHBondContact O-OH 3.41Å; Y30-Y136 WeakPolarHBondContact CA-OH 3.37Å; Y30-Y136 VanDerWaalsContact CB-OH 3.24Å; Y30-Y136 WeakPolarHBondContact CB-OH 3.4Å; Y30-Y136 HydrophobicContact CD1-CE1 4.15Å; Y30-Y136 AromaticContact CD2-CE1 3.8Å; Y30-Y136 HydrophobicContact CD2-CE1 3.8Å; Y30-Y136 VanDerWaalsContact CD2-OH 3.3Å; Y30-Y136 WeakPolarHBondContact CD2-OH 3.14Å; Y30-Y136 HydrophobicContact CE1-CE1 4.47Å; Y30-Y136 HydrophobicContact CE2-CE1 4.16Å; Y30-Y136 AromaticContact CG-CE1 3.82Å; Y30-Y136 HydrophobicContact CG-CE1 3.82Å; W132-Y136 VanDerWaalsContact O-CB 3.26Å; W132-Y136 WeakPolarHBondContact O-CB 3.34Å; W132-Y136 PolarHBondContact O-N 3.33Å; F133-Y136 HydrophobicContact CD2-CD1 4.46Å; F133-Y136 PolarHBondContact O-N 2.98Å; T134-Y136 VanDerWaalsContact C-N 3.35Å; Y136-R140 WeakPolarHBondContact O-CG 3.44Å; Y136-R140 PolarHBondContact O-NE 3.19Å
137	C	95.9	Very high	96.9	Very high	1 Å²	1	16.6 Å²	16.6	1%	0.007	8%	0.082	C	C	.	.	H	α-helix	trans	-94.3	-39	-174.5	-77.8	0	0	0	0	113.7	F133 P139 R140 C145 F384	F133-C137 HydrophobicContact CE1-CB 4.24Å; F133-C137 HydrophobicContact CZ-CB 4.48Å; F133-C137 WeakPolarHBondContact CZ-SG 3.31Å; F133-C137 WeakPolarHBondContact O-CB 3.36Å; F133-C137 PolarHBondContact O-N 2.89Å; C137-P139 VanDerWaalsContact C-CD 3.48Å; C137-R140 VanDerWaalsContact O-CB 3.32Å; C137-R140 WeakPolarHBondContact O-CB 3.22Å; C137-R140 PolarHBondContact O-N 3.22Å; C137-C145 PolarHBondContact O-SG 2.86Å; C137-F384 HydrophobicContact CB-CD1 4.43Å; C137-F384 HydrophobicContact CB-CE1 3.87Å; C137-F384 HydrophobicContact CB-CZ 3.95Å
138	A	96.6	Very high	96.9	Very high	0 Å²	0	15.9 Å²	15.9	0%	0	8%	0.079	C	C	.	.	T	Hydrogen-bonded Turn	trans	-55.6	-39.9	-166.6	0	0	0	0	0	115.3	A101 T134 R140 W148	A101-A138 HydrophobicContact CB-CB 3.87Å; T134-A138 HydrophobicContact CG2-CB 4.35Å; T134-A138 WeakPolarHBondContact O-CB 3.49Å; T134-A138 PolarHBondContact O-N 3.01Å; A138-R140 VanDerWaalsContact C-N 3.33Å; A138-W148 HydrophobicContact CB-CE3 4.45Å; A138-W148 HydrophobicContact CB-CH2 3.81Å; A138-W148 HydrophobicContact CB-CZ3 3.71Å
139	P	96.4	Very high	96.9	Very high	0 Å²	0	16 Å²	16	0%	0	8%	0.08	C	C	.	.	T	Hydrogen-bonded Turn	trans	-85.8	2	177.7	2.2	16.9	0	0	0	113.8	N22 A23 I26 Q94 I135 C137	N22-P139 HydrophobicContact CB-CG 4.12Å; N22-P139 VanDerWaalsContact CG-CG 3.46Å; N22-P139 WeakPolarHBondContact ND2-CG 3.39Å; A23-P139 HydrophobicContact CB-CB 3.8Å; I26-P139 HydrophobicContact CD1-CB 3.86Å; I26-P139 HydrophobicContact CD1-CG 3.51Å; Q94-P139 WeakPolarHBondContact CA-O 3.5Å; Q94-P139 WeakPolarHBondContact CB-O 3.42Å; I135-P139 VanDerWaalsContact O-CD 3.31Å; I135-P139 WeakPolarHBondContact O-CD 3.38Å; C137-P139 VanDerWaalsContact C-CD 3.48Å
140	R	96.5	Very high	96.9	Very high	0 Å²	0	16.2 Å²	16.2	0%	0	8%	0.08	C	C	.	.	S	Bend	trans	-74.4	147.4	177.5	-68.8	-171.8	175	-89	-6.8	111.4	I26 T28 E34 H97 Y136 C137 A138 L142	I26-R140 HydrophobicContact CD1-CG 4.29Å; T28-R140 VanDerWaalsContact O-CZ 3.29Å; T28-R140 PolarHBondContact O-NH1 2.98Å; T28-R140 PolarHBondContact O-NH2 2.88Å; T28-R140 PolarHBondContact OG1-NH2 2.88Å; E34-R140 WeakPolarHBondContact OE1-CB 3.33Å; E34-R140 WeakPolarHBondContact OE1-CG 3.47Å; E34-R140 IonicContact OE1-NH1 3.89Å; E34-R140 PolarHBondContact OE1-NH1 3.41Å; E34-R140 IonicContact OE2-CZ 2.72Å; E34-R140 IonicContact OE2-NH1 3.16Å; E34-R140 PolarHBondContact OE2-NH1 3.4Å; H97-R140 PolarHBondContact CD2-O 2.91Å; Y136-R140 WeakPolarHBondContact O-CG 3.44Å; Y136-R140 PolarHBondContact O-NE 3.19Å; C137-R140 VanDerWaalsContact O-CB 3.32Å; C137-R140 WeakPolarHBondContact O-CB 3.22Å; C137-R140 PolarHBondContact O-N 3.22Å; A138-R140 VanDerWaalsContact C-N 3.33Å; R140-L142 HydrophobicContact CB-CD1 4.33Å; R140-L142 HydrophobicContact CB-CG 4.48Å; R140-L142 PolarHBondContact O-N 2.97Å
141	S	95.7	Very high	97	Very high	0 Å²	0	13.5 Å²	13.5	0%	0	6%	0.061	C	C	.	.	S	Bend	trans	-77.8	42.4	-178	52.6	0	0	0	0	114	E34 S38 I39 H67	E34-S141 WeakPolarHBondContact CG-OG 3.31Å; E34-S141 PolarHBondContact O-OG 3.27Å; S38-S141 WeakPolarHBondContact CB-O 3.44Å; S38-S141 PolarHBondContact OG-O 3.36Å; I39-S141 WeakPolarHBondContact CD1-OG 3.47Å; I39-S141 WeakPolarHBondContact CG1-OG 3.38Å; H67-S141 PolarHBondContact CE1-O 3.16Å
142	L	96.3	Very high	97	Very high	2 Å²	2	13.5 Å²	13.5	1%	0.01	6%	0.062	C	C	.	.			trans	-97.9	140.9	178.4	-72.1	166	0	0	0	110.7	Y30 V31 D33 E34 R140 N144 C145 I146	Y30-L142 HydrophobicContact CD1-CD1 3.7Å; Y30-L142 HydrophobicContact CE1-CD1 4.08Å; V31-L142 HydrophobicContact CG2-CD1 3.96Å; V31-L142 HydrophobicContact CG2-CD2 3.71Å; V31-L142 HydrophobicContact CG2-CG 4.43Å; D33-L142 HydrophobicContact CB-CD2 4.08Å; E34-L142 HydrophobicContact CB-CD2 3.85Å; E34-L142 HydrophobicContact CB-CG 4.12Å; E34-L142 HydrophobicContact CG-CG 4.34Å; R140-L142 HydrophobicContact CB-CD1 4.33Å; R140-L142 HydrophobicContact CB-CG 4.48Å; R140-L142 PolarHBondContact O-N 2.97Å; L142-N144 HydrophobicContact CB-CB 4.49Å; L142-N144 PolarHBondContact O-N 3.12Å; L142-C145 HydrophobicContact CB-CB 4.48Å; L142-C145 WeakPolarHBondContact O-CB 3.27Å; L142-C145 PolarHBondContact O-N 2.9Å; L142-I146 PolarHBondContact O-N 3.48Å
143	S	96.4	Very high	97.1	Very high	16 Å²	16	9.6 Å²	9.6	11%	0.112	5%	0.048	C	C	.	.	H	α-helix	trans	-61.2	-27.1	171	54.4	0	0	0	0	112.1	H67 C145 I146 E147 R196	H67-S143 PolarHBondContact CE1-N 2.97Å; H67-S143 VanDerWaalsContact CE1-N 3.28Å; S143-C145 VanDerWaalsContact C-N 3.29Å; S143-C145 PolarHBondContact O-N 3.22Å; S143-I146 PolarHBondContact O-N 3.27Å; S143-E147 PolarHBondContact O-N 3.45Å; S143-R196 PolarHBondContact OG-NH1 3.4Å
144	N	96.3	Very high	97.1	Very high	1 Å²	1	9.5 Å²	9.5	1%	0.005	5%	0.048	C	C	.	.	H	α-helix	trans	-64	-31.2	171.6	-71.3	106.4	0	0	0	112.9	L142 E147 W148 R196 R381	L142-N144 HydrophobicContact CB-CB 4.49Å; L142-N144 PolarHBondContact O-N 3.12Å; N144-E147 PolarHBondContact ND2-OE2 3.1Å; N144-E147 VanDerWaalsContact ND2-OE2 3.08Å; N144-E147 PolarHBondContact O-N 3.33Å; N144-W148 WeakPolarHBondContact O-CB 3.28Å; N144-W148 PolarHBondContact O-N 3.26Å; N144-R196 VanDerWaalsContact CG-CZ 3.44Å; N144-R196 PolarHBondContact ND2-NE 2.82Å; N144-R196 VanDerWaalsContact ND2-NE 3.19Å; N144-R196 PolarHBondContact ND2-NH2 3.42Å; N144-R196 VanDerWaalsContact OD1-CZ 3.25Å; N144-R196 PolarHBondContact OD1-NH1 3.31Å; N144-R381 HydrophobicContact CB-CB 4.22Å; N144-R381 HydrophobicContact CB-CG 4.5Å; N144-R381 WeakPolarHBondContact OD1-CD 3.47Å; N144-R381 PolarHBondContact OD1-NE 2.91Å
145	C	97.3	Very high	97	Very high	2 Å²	2	9.7 Å²	9.7	1%	0.014	5%	0.049	C	C	.	.	H	α-helix	trans	-72.3	-36.2	176.7	-61.3	0	0	0	0	110.6	C137 L142 S143 W148 C149	C137-C145 PolarHBondContact O-SG 2.86Å; L142-C145 HydrophobicContact CB-CB 4.48Å; L142-C145 WeakPolarHBondContact O-CB 3.27Å; L142-C145 PolarHBondContact O-N 2.9Å; S143-C145 VanDerWaalsContact C-N 3.29Å; S143-C145 PolarHBondContact O-N 3.22Å; C145-W148 PolarHBondContact O-N 3.06Å; C145-C149 PolarHBondContact O-N 3.28Å; C145-C149 PolarHBondContact O-SG 2.99Å
146	I	97.5	Very high	97	Very high	8 Å²	8	7.5 Å²	7.5	4%	0.041	4%	0.038	C	C	.	.	H	α-helix	trans	-68.2	-43.1	171.4	-60	-57.7	0	0	0	111.3	F100 L142 S143 W148 C149 L150 I195	F100-I146 HydrophobicContact CB-CD1 4.3Å; F100-I146 HydrophobicContact CD2-CD1 3.74Å; F100-I146 HydrophobicContact CE2-CD1 4.36Å; F100-I146 HydrophobicContact CG-CD1 4.18Å; L142-I146 PolarHBondContact O-N 3.48Å; S143-I146 PolarHBondContact O-N 3.27Å; I146-W148 VanDerWaalsContact C-N 3.29Å; I146-W148 PolarHBondContact O-N 2.94Å; I146-C149 WeakPolarHBondContact O-CB 3.13Å; I146-C149 PolarHBondContact O-N 3.43Å; I146-L150 HydrophobicContact CG2-CD1 3.87Å; I146-L150 HydrophobicContact CG2-CG 4.17Å; I146-L150 WeakPolarHBondContact O-CB 3.44Å; I146-L150 VanDerWaalsContact O-CG 3.3Å; I146-L150 WeakPolarHBondContact O-CG 3.46Å; I146-L150 PolarHBondContact O-N 3.3Å; I146-I195 HydrophobicContact CG2-CD1 3.85Å
147	E	97.7	Very high	96.9	Very high	3 Å²	3	8 Å²	8	1%	0.014	4%	0.04	C	C	.	.	H	α-helix	trans	-55.6	-44	172.4	175.9	-175.4	-143.2	0	0	111.4	S143 N144 L150 C151 R196 T198 A199 P385	S143-E147 PolarHBondContact O-N 3.45Å; N144-E147 PolarHBondContact ND2-OE2 3.1Å; N144-E147 VanDerWaalsContact ND2-OE2 3.08Å; N144-E147 PolarHBondContact O-N 3.33Å; E147-L150 PolarHBondContact O-N 3.06Å; E147-C151 VanDerWaalsContact O-CB 3.24Å; E147-C151 WeakPolarHBondContact O-CB 3.34Å; E147-C151 PolarHBondContact O-N 2.99Å; E147-R196 HydrophobicContact CB-CG 4.49Å; E147-R196 WeakPolarHBondContact OE2-CD 3.46Å; E147-R196 IonicContact OE2-NE 2.88Å; E147-T198 PolarHBondContact OE1-OG1 3.24Å; E147-T198 VanDerWaalsContact OE1-OG1 3.06Å; E147-A199 HydrophobicContact CG-CB 4.22Å; E147-A199 WeakPolarHBondContact OE1-CA 3.41Å; E147-A199 PolarHBondContact OE1-N 2.98Å; E147-P385 HydrophobicContact CG-CG 4.13Å
148	W	98	Very high	96.8	Very high	0 Å²	0	8.1 Å²	8.1	0%	0	4%	0.041	C	C	.	.	H	α-helix	trans	-63.3	-43.9	174.9	169.1	87.1	0	0	0	112.7	A101 A104 H128 T134 A138 N144 C145 I146 C151 I152 F384	A101-W148 HydrophobicContact CB-CH2 4.45Å; A101-W148 HydrophobicContact CB-CZ3 3.95Å; A104-W148 HydrophobicContact CB-CZ3 4.2Å; H128-W148 AromaticContact CE1-CE2 3.97Å; H128-W148 AromaticContact CE1-CZ2 3.37Å; H128-W148 WeakPolarHBondContact CE1-CZ2 3.45Å; H128-W148 AromaticContact NE2-CH2 3.78Å; H128-W148 AromaticContact NE2-CZ2 3.17Å; H128-W148 WeakPolarHBondContact NE2-CZ2 3.43Å; T134-W148 HydrophobicContact CG2-CH2 3.96Å; T134-W148 HydrophobicContact CG2-CZ2 3.58Å; A138-W148 HydrophobicContact CB-CE3 4.45Å; A138-W148 HydrophobicContact CB-CH2 3.81Å; A138-W148 HydrophobicContact CB-CZ3 3.71Å; N144-W148 WeakPolarHBondContact O-CB 3.28Å; N144-W148 PolarHBondContact O-N 3.26Å; C145-W148 PolarHBondContact O-N 3.06Å; I146-W148 VanDerWaalsContact C-N 3.29Å; I146-W148 PolarHBondContact O-N 2.94Å; W148-C151 WeakPolarHBondContact O-CB 3.45Å; W148-C151 PolarHBondContact O-N 3.34Å; W148-I152 HydrophobicContact CD2-CD1 4.07Å; W148-I152 HydrophobicContact CH2-CD1 4.24Å; W148-I152 HydrophobicContact CZ2-CD1 3.73Å; W148-I152 WeakPolarHBondContact O-CG1 3.45Å; W148-I152 PolarHBondContact O-N 3.39Å; W148-F384 HydrophobicContact CB-CD1 3.53Å; W148-F384 HydrophobicContact CB-CE1 3.81Å; W148-F384 HydrophobicContact CB-CG 4.22Å; W148-F384 AromaticContact CD1-CD1 3.72Å; W148-F384 AromaticContact CD1-CD2 3.85Å; W148-F384 AromaticContact CD1-CE1 3.77Å; W148-F384 AromaticContact CD1-CE2 3.89Å; W148-F384 AromaticContact CD1-CG 3.76Å; W148-F384 AromaticContact CD1-CZ 3.85Å; W148-F384 HydrophobicContact CD2-CD1 4.15Å; W148-F384 AromaticContact CD2-CE1 3.54Å; W148-F384 HydrophobicContact CD2-CE1 3.54Å; W148-F384 HydrophobicContact CD2-CE2 4.47Å; W148-F384 AromaticContact CD2-CZ 3.72Å; W148-F384 HydrophobicContact CD2-CZ 3.72Å; W148-F384 AromaticContact CE2-CE1 3.92Å; W148-F384 AromaticContact CE2-CZ 3.56Å; W148-F384 HydrophobicContact CE3-CE1 4.04Å; W148-F384 HydrophobicContact CE3-CZ 4.33Å; W148-F384 AromaticContact CG-CD1 3.52Å; W148-F384 HydrophobicContact CG-CD1 3.52Å; W148-F384 HydrophobicContact CG-CD2 4.44Å; W148-F384 AromaticContact CG-CE1 3.44Å; W148-F384 HydrophobicContact CG-CE1 3.44Å; W148-F384 VanDerWaalsContact CG-CE1 3.44Å; W148-F384 HydrophobicContact CG-CE2 4.37Å; W148-F384 HydrophobicContact CG-CG 4.04Å; W148-F384 AromaticContact CG-CZ 3.88Å; W148-F384 HydrophobicContact CG-CZ 3.88Å; W148-F384 HydrophobicContact CZ2-CZ 4.04Å; W148-F384 AromaticContact NE1-CE2 3.63Å; W148-F384 AromaticContact NE1-CZ 3.62Å
149	C	98.5	Very high	96.6	Very high	3 Å²	3	9 Å²	9	2%	0.02	5%	0.046	C	C	.	.	H	α-helix	trans	-59.7	-50.6	174.4	-66.8	0	0	0	0	111.2	A104 C145 I146 C151 I152 I153	A104-C149 HydrophobicContact CB-CB 3.94Å; C145-C149 PolarHBondContact O-N 3.28Å; C145-C149 PolarHBondContact O-SG 2.99Å; I146-C149 WeakPolarHBondContact O-CB 3.13Å; I146-C149 PolarHBondContact O-N 3.43Å; C149-C151 VanDerWaalsContact C-N 3.31Å; C149-C151 PolarHBondContact O-N 2.84Å; C149-I152 PolarHBondContact O-N 2.84Å; C149-I153 VanDerWaalsContact O-CG1 3.24Å; C149-I153 WeakPolarHBondContact O-CG1 3.13Å; C149-I153 PolarHBondContact O-N 3.23Å
150	L	98.3	Very high	96.2	Very high	27 Å²	27	9.1 Å²	9.1	14%	0.141	5%	0.047	C	C	.	.	H	α-helix	trans	-64.9	-34.6	-179.3	-68.3	176.3	0	0	0	112.1	I146 E147 G154 I188 V191 I195	I146-L150 HydrophobicContact CG2-CD1 3.87Å; I146-L150 HydrophobicContact CG2-CG 4.17Å; I146-L150 WeakPolarHBondContact O-CB 3.44Å; I146-L150 VanDerWaalsContact O-CG 3.3Å; I146-L150 WeakPolarHBondContact O-CG 3.46Å; I146-L150 PolarHBondContact O-N 3.3Å; E147-L150 PolarHBondContact O-N 3.06Å; L150-G154 WeakPolarHBondContact O-CA 3.45Å; L150-G154 PolarHBondContact O-N 2.88Å; L150-I188 HydrophobicContact CB-CG2 4.04Å; L150-I188 HydrophobicContact CD2-CG2 4.15Å; L150-I188 WeakPolarHBondContact O-CG2 3.48Å; L150-V191 HydrophobicContact CD1-CG1 4Å; L150-I195 HydrophobicContact CD1-CD1 3.79Å
151	C	98.1	Very high	95.4	Very high	1 Å²	1	10.3 Å²	10.3	1%	0.007	5%	0.053	C	C	.	.	H	α-helix	trans	-56.3	-53.9	171.8	175.6	0	0	0	0	110.7	E147 W148 C149 G154 L155 I202 P385	E147-C151 VanDerWaalsContact O-CB 3.24Å; E147-C151 WeakPolarHBondContact O-CB 3.34Å; E147-C151 PolarHBondContact O-N 2.99Å; W148-C151 WeakPolarHBondContact O-CB 3.45Å; W148-C151 PolarHBondContact O-N 3.34Å; C149-C151 VanDerWaalsContact C-N 3.31Å; C149-C151 PolarHBondContact O-N 2.84Å; C151-G154 PolarHBondContact O-N 3.43Å; C151-L155 WeakPolarHBondContact O-CB 3.25Å; C151-L155 VanDerWaalsContact O-CG 3.22Å; C151-L155 WeakPolarHBondContact O-CG 3.36Å; C151-L155 PolarHBondContact O-N 3.3Å; C151-I202 WeakPolarHBondContact SG-CD1 3.38Å; C151-P385 HydrophobicContact CB-CB 4.15Å
152	I	98.4	Very high	94.8	Very high	1 Å²	1	10.6 Å²	10.6	1%	0.005	6%	0.055	C	C	.	.	H	α-helix	trans	-62.7	-48.1	-179	-65.6	169.1	0	0	0	111.4	A104 H107 L108 W148 C149 G154 L155 S156 P388	A104-I152 HydrophobicContact CB-CB 4.32Å; A104-I152 HydrophobicContact CB-CD1 4.17Å; A104-I152 HydrophobicContact CB-CG2 4.46Å; A104-I152 WeakPolarHBondContact O-CG2 3.43Å; H107-I152 HydrophobicContact CB-CG2 4.29Å; L108-I152 HydrophobicContact CB-CG2 3.68Å; L108-I152 HydrophobicContact CD1-CG2 4.46Å; W148-I152 HydrophobicContact CD2-CD1 4.07Å; W148-I152 HydrophobicContact CH2-CD1 4.24Å; W148-I152 HydrophobicContact CZ2-CD1 3.73Å; W148-I152 WeakPolarHBondContact O-CG1 3.45Å; W148-I152 PolarHBondContact O-N 3.39Å; C149-I152 PolarHBondContact O-N 2.84Å; I152-G154 PolarHBondContact O-N 2.96Å; I152-L155 PolarHBondContact O-N 3.45Å; I152-S156 PolarHBondContact O-N 3.37Å; I152-P388 HydrophobicContact CD1-CB 3.88Å; I152-P388 HydrophobicContact CD1-CG 3.97Å; I152-P388 HydrophobicContact CG1-CB 3.74Å; I152-P388 HydrophobicContact CG1-CG 3.64Å
153	I	98.1	Very high	94.3	Very high	22 Å²	22	10.5 Å²	10.5	11%	0.113	6%	0.055	C	C	.	.	H	α-helix	trans	-62.9	-45.7	-179.2	-60.8	165.7	0	0	0	109.6	I103 H107 C149 L155 S156 Y157 I188	I103-I153 HydrophobicContact CG2-CD1 3.8Å; I103-I153 HydrophobicContact CG2-CG1 4.33Å; H107-I153 HydrophobicContact CB-CG1 4.06Å; C149-I153 VanDerWaalsContact O-CG1 3.24Å; C149-I153 WeakPolarHBondContact O-CG1 3.13Å; C149-I153 PolarHBondContact O-N 3.23Å; I153-L155 PolarHBondContact O-N 2.91Å; I153-S156 WeakPolarHBondContact O-CB 3.38Å; I153-S156 PolarHBondContact O-N 3.22Å; I153-S156 VanDerWaalsContact O-N 3.13Å; I153-S156 PolarHBondContact O-OG 3.45Å; I153-Y157 HydrophobicContact CG2-CD2 4.17Å; I153-Y157 HydrophobicContact CG2-CE2 3.91Å; I153-Y157 VanDerWaalsContact O-CD2 3.27Å; I153-Y157 WeakPolarHBondContact O-CD2 3.28Å; I153-Y157 PolarHBondContact O-N 3.07Å; I153-I188 HydrophobicContact CG2-CD1 3.74Å
154	G	97.2	Very high	93.6	Very high	0 Å²	0	9.8 Å²	9.8	0%	0	5%	0.049	C	C	.	.	H	α-helix	trans	-60.4	-45.2	177.6	0	0	0	0	0	112	L150 C151 I152 S156 Y157 Y158 F185	L150-G154 WeakPolarHBondContact O-CA 3.45Å; L150-G154 PolarHBondContact O-N 2.88Å; C151-G154 PolarHBondContact O-N 3.43Å; I152-G154 PolarHBondContact O-N 2.96Å; G154-S156 PolarHBondContact O-N 2.89Å; G154-Y157 CarbonylContact O-C 3.6Å; G154-Y157 PolarHBondContact O-N 3.48Å; G154-Y158 PolarHBondContact O-N 3.19Å; G154-F185 WeakPolarHBondContact O-CB 3.5Å
155	L	96.6	Very high	92.4	Very high	4 Å²	4	10 Å²	10	2%	0.021	5%	0.05	C	C	.	.	H	α-helix	trans	-62	-33.1	176.5	-71.1	173.1	0	0	0	111.6	L111 C151 I152 I153 Y157 Y158 W160 W203 L206 L389	L111-L155 WeakPolarHBondContact CD1-O 3.45Å; L111-L155 HydrophobicContact CD2-CB 3.75Å; C151-L155 WeakPolarHBondContact O-CB 3.25Å; C151-L155 VanDerWaalsContact O-CG 3.22Å; C151-L155 WeakPolarHBondContact O-CG 3.36Å; C151-L155 PolarHBondContact O-N 3.3Å; I152-L155 PolarHBondContact O-N 3.45Å; I153-L155 PolarHBondContact O-N 2.91Å; L155-Y157 VanDerWaalsContact C-N 3.26Å; L155-Y157 PolarHBondContact O-N 3.35Å; L155-Y158 VanDerWaalsContact O-CB 3.31Å; L155-Y158 WeakPolarHBondContact O-CB 3.36Å; L155-Y158 PolarHBondContact O-N 3.2Å; L155-W160 HydrophobicContact CB-CZ2 4.44Å; L155-W160 HydrophobicContact CD2-CZ2 3.99Å; L155-W160 PolarHBondContact O-NE1 3.43Å; L155-W203 HydrophobicContact CG-CH2 4.48Å; L155-L206 HydrophobicContact CD2-CD1 3.7Å; L155-L389 HydrophobicContact CD1-CD2 3.89Å
156	S	95.2	Very high	90.7	Very high	11 Å²	11	12.3 Å²	12.3	8%	0.077	6%	0.064	C	C	.	.	H	α-helix	trans	-66.1	-24.7	174.7	81.8	0	0	0	0	114.3	H107 I152 I153 G154	H107-S156 PolarHBondContact ND1-OG 2.59Å; I152-S156 PolarHBondContact O-N 3.37Å; I153-S156 WeakPolarHBondContact O-CB 3.38Å; I153-S156 PolarHBondContact O-N 3.22Å; I153-S156 VanDerWaalsContact O-N 3.13Å; I153-S156 PolarHBondContact O-OG 3.45Å; G154-S156 PolarHBondContact O-N 2.89Å
157	Y	94.4	Very high	89.2	Confident	67 Å²	67	15.5 Å²	15.5	26%	0.263	8%	0.081	S	C	.	.	H	α-helix	trans	-95.8	-9.9	174.8	-72.7	-72.6	0	0	0	113.4	H107 I153 G154 L155 W184 I188	H107-Y157 AromaticContact CE1-CE2 3.59Å; H107-Y157 AromaticContact CE1-CZ 3.87Å; I153-Y157 HydrophobicContact CG2-CD2 4.17Å; I153-Y157 HydrophobicContact CG2-CE2 3.91Å; I153-Y157 VanDerWaalsContact O-CD2 3.27Å; I153-Y157 WeakPolarHBondContact O-CD2 3.28Å; I153-Y157 PolarHBondContact O-N 3.07Å; G154-Y157 CarbonylContact O-C 3.6Å; G154-Y157 PolarHBondContact O-N 3.48Å; L155-Y157 VanDerWaalsContact C-N 3.26Å; L155-Y157 PolarHBondContact O-N 3.35Å; Y157-W184 HydrophobicContact CD1-CB 4.01Å; Y157-W184 HydrophobicContact CD2-CB 4.39Å; Y157-W184 HydrophobicContact CE1-CB 4.48Å; Y157-W184 HydrophobicContact CG-CB 3.95Å; Y157-I188 HydrophobicContact CD2-CD1 3.65Å; Y157-I188 HydrophobicContact CE2-CD1 4.15Å
158	Y	94.2	Very high	87.5	Confident	2 Å²	2	18.9 Å²	18.9	1%	0.008	10%	0.097	C	C	.	.	S	Bend	trans	-60.5	135.3	177.5	-172.1	-112	0	0	0	109.8	G154 L155 W160 I163 F185 L206 H210 L360	G154-Y158 PolarHBondContact O-N 3.19Å; L155-Y158 VanDerWaalsContact O-CB 3.31Å; L155-Y158 WeakPolarHBondContact O-CB 3.36Å; L155-Y158 PolarHBondContact O-N 3.2Å; Y158-W160 AromaticContact CD1-CD2 3.75Å; Y158-W160 HydrophobicContact CD1-CD2 3.75Å; Y158-W160 AromaticContact CD1-CE2 3.66Å; Y158-W160 HydrophobicContact CD1-CE3 4.25Å; Y158-W160 HydrophobicContact CD1-CG 4.06Å; Y158-W160 HydrophobicContact CD1-CZ2 4.08Å; Y158-W160 AromaticContact CD1-NE1 3.86Å; Y158-W160 HydrophobicContact CE1-CD2 4.39Å; Y158-W160 HydrophobicContact CE1-CE3 4.46Å; Y158-W160 PolarHBondContact O-N 2.99Å; Y158-I163 HydrophobicContact CD1-CD1 3.82Å; Y158-I163 HydrophobicContact CD2-CD1 4.28Å; Y158-I163 HydrophobicContact CE1-CD1 3.16Å; Y158-I163 HydrophobicContact CE1-CG1 4.46Å; Y158-I163 HydrophobicContact CE2-CD1 3.66Å; Y158-I163 HydrophobicContact CG-CD1 4.36Å; Y158-I163 VanDerWaalsContact OH-CD1 3.31Å; Y158-I163 WeakPolarHBondContact OH-CD1 3.3Å; Y158-F185 HydrophobicContact CD2-CD1 4.42Å; Y158-F185 AromaticContact CD2-CD2 3.86Å; Y158-F185 HydrophobicContact CD2-CD2 3.86Å; Y158-F185 HydrophobicContact CD2-CE1 4.44Å; Y158-F185 AromaticContact CD2-CE2 3.87Å; Y158-F185 HydrophobicContact CD2-CE2 3.87Å; Y158-F185 HydrophobicContact CD2-CG 4.16Å; Y158-F185 HydrophobicContact CD2-CZ 4.17Å; Y158-F185 HydrophobicContact CE2-CE2 4.13Å; Y158-F185 HydrophobicContact CE2-CZ 4.35Å; Y158-L206 HydrophobicContact CE1-CD2 4.23Å; Y158-L206 HydrophobicContact CE2-CB 3.98Å; Y158-L206 HydrophobicContact CE2-CD2 4.45Å; Y158-L206 PolarHBondContact OH-O 2.94Å; Y158-L206 VanDerWaalsContact OH-O 3.14Å; Y158-H210 HydrophobicContact CE2-CB 4.22Å; Y158-L360 HydrophobicContact CE1-CD2 4.1Å
159	P	90.7	Very high	85.7	Confident	18 Å²	18	25.7 Å²	25.7	12%	0.117	13%	0.129	C	C	.	.			trans	-80.4	62.8	-172	32	-35.3	0	0	0	111.7	N161 V162 I163 F185 H210	P159-N161 PolarHBondContact O-N 3.05Å; P159-N161 VanDerWaalsContact O-N 3.16Å; P159-V162 HydrophobicContact CB-CB 4.32Å; P159-V162 HydrophobicContact CB-CG2 4.3Å; P159-V162 PolarHBondContact O-N 3.17Å; P159-I163 HydrophobicContact CG-CD1 3.85Å; P159-I163 HydrophobicContact CG-CG1 4.44Å; P159-I163 WeakPolarHBondContact O-CG1 3.11Å; P159-I163 PolarHBondContact O-N 2.94Å; P159-I163 VanDerWaalsContact O-N 3.13Å; P159-F185 HydrophobicContact CG-CE1 4.11Å; P159-H210 WeakPolarHBondContact CG-CD2 3.43Å
160	W	88.2	Confident	84	Confident	3 Å²	3	29.1 Å²	29.1	1%	0.011	14%	0.144	C	C	.	.	H	α-helix	trans	-49.2	-44	-177.6	-66.5	96.7	0	0	0	112.9	L111 L115 L155 Y158 V162 I163 C164 P357 L360	L111-W160 HydrophobicContact CD1-CZ2 4.22Å; L115-W160 HydrophobicContact CD1-CD2 4.29Å; L115-W160 HydrophobicContact CD1-CE3 4.47Å; L115-W160 HydrophobicContact CD1-CZ2 4.45Å; L115-W160 HydrophobicContact CD2-CB 3.62Å; L115-W160 HydrophobicContact CD2-CD2 3.7Å; L115-W160 HydrophobicContact CD2-CE3 4Å; L115-W160 HydrophobicContact CD2-CG 3.53Å; L155-W160 HydrophobicContact CB-CZ2 4.44Å; L155-W160 HydrophobicContact CD2-CZ2 3.99Å; L155-W160 PolarHBondContact O-NE1 3.43Å; Y158-W160 AromaticContact CD1-CD2 3.75Å; Y158-W160 HydrophobicContact CD1-CD2 3.75Å; Y158-W160 AromaticContact CD1-CE2 3.66Å; Y158-W160 HydrophobicContact CD1-CE3 4.25Å; Y158-W160 HydrophobicContact CD1-CG 4.06Å; Y158-W160 HydrophobicContact CD1-CZ2 4.08Å; Y158-W160 AromaticContact CD1-NE1 3.86Å; Y158-W160 HydrophobicContact CE1-CD2 4.39Å; Y158-W160 HydrophobicContact CE1-CE3 4.46Å; Y158-W160 PolarHBondContact O-N 2.99Å; W160-V162 PolarHBondContact O-N 2.91Å; W160-I163 PolarHBondContact O-N 3.03Å; W160-I163 VanDerWaalsContact O-N 3.15Å; W160-C164 WeakPolarHBondContact O-CB 3.36Å; W160-C164 PolarHBondContact O-N 3.45Å; W160-C164 PolarHBondContact O-SG 3.38Å; W160-P357 HydrophobicContact CE3-CB 4.17Å; W160-P357 HydrophobicContact CZ3-CB 4.37Å; W160-L360 HydrophobicContact CE3-CD2 4.29Å; W160-L360 HydrophobicContact CH2-CD2 4.47Å; W160-L360 HydrophobicContact CZ3-CB 4.28Å; W160-L360 HydrophobicContact CZ3-CD2 3.77Å; W160-L360 HydrophobicContact CZ3-CG 4.3Å
161	N	81.2	Confident	82.2	Confident	25 Å²	25	28.3 Å²	28.3	13%	0.134	14%	0.14	C	C	.	.	H	α-helix	trans	-60.2	-45.8	-179.4	-67.3	15.3	0	0	0	111.8	Q114 P159 I163 H165 F170 T174	Q114-N161 PolarHBondContact NE2-OD1 2.84Å; P159-N161 PolarHBondContact O-N 3.05Å; P159-N161 VanDerWaalsContact O-N 3.16Å; N161-I163 VanDerWaalsContact C-N 3.25Å; N161-I163 PolarHBondContact O-N 2.74Å; N161-H165 WeakPolarHBondContact O-CB 3.26Å; N161-H165 PolarHBondContact O-CD2 3.16Å; N161-H165 PolarHBondContact O-N 3.28Å; N161-F170 HydrophobicContact CB-CE1 4.07Å; N161-T174 HydrophobicContact CB-CG2 3.99Å
162	V	81.2	Confident	80.6	Confident	7 Å²	7	33.4 Å²	33.4	4%	0.042	16%	0.163	C	C	.	.	H	α-helix	trans	-66.3	-34.1	179.1	179.4	0	0	0	0	111.1	P159 W160 I171 K214 I217	P159-V162 HydrophobicContact CB-CB 4.32Å; P159-V162 HydrophobicContact CB-CG2 4.3Å; P159-V162 PolarHBondContact O-N 3.17Å; W160-V162 PolarHBondContact O-N 2.91Å; V162-I171 HydrophobicContact CG1-CG2 4.25Å; V162-K214 HydrophobicContact CG1-CD 4Å; V162-I217 HydrophobicContact CG1-CD1 4.02Å; V162-I217 WeakPolarHBondContact O-CD1 3.26Å
163	I	85.8	Confident	78.8	Confident	0 Å²	0	38.5 Å²	38.5	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-79.5	-44.2	-173.6	-69.4	167.8	0	0	0	111	Y158 P159 W160 N161 W209 H210 R213 L360	Y158-I163 HydrophobicContact CD1-CD1 3.82Å; Y158-I163 HydrophobicContact CD2-CD1 4.28Å; Y158-I163 HydrophobicContact CE1-CD1 3.16Å; Y158-I163 HydrophobicContact CE1-CG1 4.46Å; Y158-I163 HydrophobicContact CE2-CD1 3.66Å; Y158-I163 HydrophobicContact CG-CD1 4.36Å; Y158-I163 VanDerWaalsContact OH-CD1 3.31Å; Y158-I163 WeakPolarHBondContact OH-CD1 3.3Å; P159-I163 HydrophobicContact CG-CD1 3.85Å; P159-I163 HydrophobicContact CG-CG1 4.44Å; P159-I163 WeakPolarHBondContact O-CG1 3.11Å; P159-I163 PolarHBondContact O-N 2.94Å; P159-I163 VanDerWaalsContact O-N 3.13Å; W160-I163 PolarHBondContact O-N 3.03Å; W160-I163 VanDerWaalsContact O-N 3.15Å; N161-I163 VanDerWaalsContact C-N 3.25Å; N161-I163 PolarHBondContact O-N 2.74Å; I163-W209 VanDerWaalsContact CG2-CD1 3.43Å; I163-H210 HydrophobicContact CD1-CB 4.26Å; I163-R213 HydrophobicContact CG2-CG 4.5Å; I163-R213 PolarHBondContact O-NE 2.93Å; I163-R213 PolarHBondContact O-NH2 2.91Å; I163-R213 VanDerWaalsContact O-NH2 3.16Å; I163-L360 HydrophobicContact CG2-CD2 4.3Å
164	C	81.5	Confident	77.1	Confident	0 Å²	0	38.1 Å²	38.1	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-90.6	-30.6	-171.1	-61.7	0	0	0	0	113	W160 Y345 R355 P357	W160-C164 WeakPolarHBondContact O-CB 3.36Å; W160-C164 PolarHBondContact O-N 3.45Å; W160-C164 PolarHBondContact O-SG 3.38Å; C164-Y345 HydrophobicContact CB-CD1 3.8Å; C164-Y345 HydrophobicContact CB-CE1 3.48Å; C164-Y345 VanDerWaalsContact CB-CE1 3.48Å; C164-R355 CarbonylContact C-O 3.48Å; C164-R355 WeakPolarHBondContact CA-O 3.42Å; C164-R355 WeakPolarHBondContact CB-O 3.49Å; C164-P357 HydrophobicContact CB-CG 4.2Å
165	H	72.7	Confident	75.5	Confident	6 Å²	6	39.6 Å²	39.6	3%	0.028	20%	0.201	C	C	.	.			trans	-76.2	155.4	178.5	-80.7	-78.1	0	0	0	114	N161 F170 I171 R213 I343 D344	N161-H165 WeakPolarHBondContact O-CB 3.26Å; N161-H165 PolarHBondContact O-CD2 3.16Å; N161-H165 PolarHBondContact O-N 3.28Å; H165-F170 HydrophobicContact CB-CD1 4.36Å; H165-F170 AromaticContact CD2-CD1 3.56Å; H165-F170 AromaticContact CD2-CE1 3.34Å; H165-F170 WeakPolarHBondContact CD2-CE1 3.23Å; H165-F170 AromaticContact CG-CD1 3.84Å; H165-F170 AromaticContact NE2-CD1 3.76Å; H165-F170 AromaticContact NE2-CE1 3.31Å; H165-F170 VanDerWaalsContact NE2-CE1 3.31Å; H165-F170 WeakPolarHBondContact NE2-CE1 3.39Å; H165-I171 HydrophobicContact CB-CD1 4.47Å; H165-I171 HydrophobicContact CB-CG1 4.23Å; H165-R213 PolarHBondContact O-NH2 3.4Å; H165-R213 VanDerWaalsContact O-NH2 3.11Å; H165-I343 WeakPolarHBondContact CE1-CG2 3.33Å; H165-I343 VanDerWaalsContact NE2-CG2 3.27Å; H165-I343 WeakPolarHBondContact NE2-CG2 3.43Å; H165-D344 PolarHBondContact ND1-O 2.84Å; H165-D344 VanDerWaalsContact ND1-O 3.08Å
166	T	61.8	Low	73.7	Confident	50 Å²	50	43.2 Å²	43.2	31%	0.307	23%	0.227	S	C	.	.			trans	-107.1	-26.2	169	36.3	0	0	0	0	113.5	Q168	T166-Q168 PolarHBondContact O-N 2.81Å; T166-Q168 VanDerWaalsContact O-N 3.12Å
167	D	64.9	Low	72	Confident	75 Å²	75	48.7 Å²	48.7	40%	0.401	26%	0.255	S	S	.	.			trans	-66.7	111.7	-178.5	-174.2	-16.3	0	0	0	110.8	Q169 F170 I171	D167-Q169 PolarHBondContact OD1-N 2.88Å; D167-F170 HydrophobicContact CB-CB 3.98Å; D167-F170 PolarHBondContact O-N 2.97Å; D167-F170 PolarHBondContact OD1-N 3.27Å; D167-I171 WeakPolarHBondContact O-CD1 3.17Å; D167-I171 WeakPolarHBondContact O-CG1 3.31Å; D167-I171 PolarHBondContact O-N 3.11Å
168	Q	62	Low	70.5	Confident	75 Å²	75	50.4 Å²	50.4	35%	0.35	26%	0.262	S	S	.	.	H	α-helix	trans	-66	-36.3	-176.8	-70.3	178.8	-28.6	0	0	112.4	T166 I171 Q172 T220 L221	T166-Q168 PolarHBondContact O-N 2.81Å; T166-Q168 VanDerWaalsContact O-N 3.12Å; Q168-I171 PolarHBondContact O-N 3.25Å; Q168-Q172 WeakPolarHBondContact O-CG 3.37Å; Q168-Q172 PolarHBondContact O-N 3.28Å; Q168-T220 PolarHBondContact NE2-OG1 3.16Å; Q168-T220 VanDerWaalsContact NE2-OG1 3.15Å; Q168-L221 HydrophobicContact CB-CD2 4.42Å
169	Q	60.3	Low	68.9	Low	143 Å²	143	55.7 Å²	55.7	67%	0.668	29%	0.286	S	S	*	.	H	α-helix	trans	-65.6	-44.9	178.3	-68.3	-174.4	-1.6	0	0	109.9	D167 I171 Q172 L173	D167-Q169 PolarHBondContact OD1-N 2.88Å; Q169-I171 VanDerWaalsContact C-N 3.32Å; Q169-I171 PolarHBondContact O-N 3.13Å; Q169-Q172 PolarHBondContact O-N 3.48Å; Q169-L173 WeakPolarHBondContact O-CB 3.35Å; Q169-L173 WeakPolarHBondContact O-CG 3.49Å; Q169-L173 PolarHBondContact O-N 3.1Å
170	F	62.7	Low	67.5	Low	74 Å²	74	59.5 Å²	59.5	33%	0.325	31%	0.306	S	S	.	.	H	α-helix	trans	-61.8	-40.5	174.8	-173.5	-98.5	0	0	0	112.2	N161 H165 D167 T174	N161-F170 HydrophobicContact CB-CE1 4.07Å; H165-F170 HydrophobicContact CB-CD1 4.36Å; H165-F170 AromaticContact CD2-CD1 3.56Å; H165-F170 AromaticContact CD2-CE1 3.34Å; H165-F170 WeakPolarHBondContact CD2-CE1 3.23Å; H165-F170 AromaticContact CG-CD1 3.84Å; H165-F170 AromaticContact NE2-CD1 3.76Å; H165-F170 AromaticContact NE2-CE1 3.31Å; H165-F170 VanDerWaalsContact NE2-CE1 3.31Å; H165-F170 WeakPolarHBondContact NE2-CE1 3.39Å; D167-F170 HydrophobicContact CB-CB 3.98Å; D167-F170 PolarHBondContact O-N 2.97Å; D167-F170 PolarHBondContact OD1-N 3.27Å; F170-T174 WeakPolarHBondContact CE1-OG1 3.39Å; F170-T174 VanDerWaalsContact O-CB 3.29Å; F170-T174 WeakPolarHBondContact O-CB 3.32Å; F170-T174 PolarHBondContact O-N 2.69Å; F170-T174 PolarHBondContact O-OG1 3.26Å
171	I	61	Low	66.7	Low	11 Å²	11	64 Å²	64	6%	0.056	32%	0.323	C	S	.	.	H	α-helix	trans	-63.5	-44.2	177.2	-69.4	160.5	0	0	0	111.1	V162 H165 D167 Q168 Q169 T174 A175 I217	V162-I171 HydrophobicContact CG1-CG2 4.25Å; H165-I171 HydrophobicContact CB-CD1 4.47Å; H165-I171 HydrophobicContact CB-CG1 4.23Å; D167-I171 WeakPolarHBondContact O-CD1 3.17Å; D167-I171 WeakPolarHBondContact O-CG1 3.31Å; D167-I171 PolarHBondContact O-N 3.11Å; Q168-I171 PolarHBondContact O-N 3.25Å; Q169-I171 VanDerWaalsContact C-N 3.32Å; Q169-I171 PolarHBondContact O-N 3.13Å; I171-T174 PolarHBondContact O-N 2.88Å; I171-A175 WeakPolarHBondContact O-CB 3.38Å; I171-A175 PolarHBondContact O-N 2.64Å; I171-I217 HydrophobicContact CD1-CD1 4.11Å; I171-I217 HydrophobicContact CG2-CD1 4.48Å; I171-I217 HydrophobicContact CG2-CG2 4.25Å
172	Q	63.7	Low	66.3	Low	107 Å²	107	63.9 Å²	63.9	50%	0.5	32%	0.323	S	S	.	.	H	α-helix	trans	-63.5	-48.2	178.7	-74.6	179.4	-3.6	0	0	111.6	Q168 Q169 T174 A175 S176 L221	Q168-Q172 WeakPolarHBondContact O-CG 3.37Å; Q168-Q172 PolarHBondContact O-N 3.28Å; Q169-Q172 PolarHBondContact O-N 3.48Å; Q172-T174 VanDerWaalsContact C-N 3.29Å; Q172-T174 PolarHBondContact O-N 3.3Å; Q172-A175 PolarHBondContact O-N 2.91Å; Q172-S176 PolarHBondContact O-N 3.12Å; Q172-S176 PolarHBondContact O-OG 2.93Å; Q172-L221 VanDerWaalsContact NE2-CD2 3.28Å
173	L	62.4	Low	66.7	Low	108 Å²	108	67.9 Å²	67.9	57%	0.565	34%	0.34	S	S	*	.	H	α-helix	trans	-59	-39.7	175.8	-73.9	164.3	0	0	0	112.2	Q169 S176 N177	Q169-L173 WeakPolarHBondContact O-CB 3.35Å; Q169-L173 WeakPolarHBondContact O-CG 3.49Å; Q169-L173 PolarHBondContact O-N 3.1Å; L173-S176 PolarHBondContact O-OG 2.98Å; L173-N177 WeakPolarHBondContact O-CB 3.03Å; L173-N177 PolarHBondContact O-N 3.43Å; L173-N177 PolarHBondContact O-ND2 2.8Å
174	T	61.4	Low	67	Low	15 Å²	15	74.4 Å²	74.4	9%	0.092	37%	0.365	C	S	.	.	H	α-helix	trans	-72.9	-39.1	177.4	-54.4	0	0	0	0	111.1	N161 F170 I171 Q172 N177 Y178	N161-T174 HydrophobicContact CB-CG2 3.99Å; F170-T174 WeakPolarHBondContact CE1-OG1 3.39Å; F170-T174 VanDerWaalsContact O-CB 3.29Å; F170-T174 WeakPolarHBondContact O-CB 3.32Å; F170-T174 PolarHBondContact O-N 2.69Å; F170-T174 PolarHBondContact O-OG1 3.26Å; I171-T174 PolarHBondContact O-N 2.88Å; Q172-T174 VanDerWaalsContact C-N 3.29Å; Q172-T174 PolarHBondContact O-N 3.3Å; T174-N177 PolarHBondContact O-N 3.46Å; T174-Y178 HydrophobicContact CG2-CD2 3.75Å; T174-Y178 HydrophobicContact CG2-CE2 4.33Å; T174-Y178 WeakPolarHBondContact O-CB 3.49Å; T174-Y178 WeakPolarHBondContact O-CD2 3.39Å; T174-Y178 PolarHBondContact O-N 2.95Å
175	A	63.2	Low	67.6	Low	31 Å²	31	74.4 Å²	74.4	26%	0.256	37%	0.365	S	S	.	.	H	α-helix	trans	-67.4	-36.8	-179	0	0	0	0	0	112.6	I171 Q172 H179	I171-A175 WeakPolarHBondContact O-CB 3.38Å; I171-A175 PolarHBondContact O-N 2.64Å; Q172-A175 PolarHBondContact O-N 2.91Å; A175-H179 PolarHBondContact O-N 2.9Å
176	S	59.7	Low	68.8	Low	80 Å²	80	74.2 Å²	74.2	56%	0.559	36%	0.364	S	S	*	.	H	α-helix	trans	-68.5	-46.1	175.1	59.9	0	0	0	0	111.5	Q172 L173 Y178	Q172-S176 PolarHBondContact O-N 3.12Å; Q172-S176 PolarHBondContact O-OG 2.93Å; L173-S176 PolarHBondContact O-OG 2.98Å; S176-Y178 VanDerWaalsContact C-N 3.28Å; S176-Y178 PolarHBondContact O-N 3.44Å
177	N	59.3	Low	70.4	Confident	126 Å²	126	76 Å²	76	67%	0.674	37%	0.368	S	S	*	.	H	α-helix	trans	-68	-26	179.9	-75.6	-22.8	0	0	0	113.6	L173 T174	L173-N177 WeakPolarHBondContact O-CB 3.03Å; L173-N177 PolarHBondContact O-N 3.43Å; L173-N177 PolarHBondContact O-ND2 2.8Å; T174-N177 PolarHBondContact O-N 3.46Å
178	Y	62.9	Low	72	Confident	103 Å²	103	73 Å²	73	40%	0.404	35%	0.352	S	S	.	.	T	Hydrogen-bonded Turn	trans	-122.2	33.7	-171.1	-66.8	-72.5	0	0	0	114.3	T174 S176 N180 R181 P182	T174-Y178 HydrophobicContact CG2-CD2 3.75Å; T174-Y178 HydrophobicContact CG2-CE2 4.33Å; T174-Y178 WeakPolarHBondContact O-CB 3.49Å; T174-Y178 WeakPolarHBondContact O-CD2 3.39Å; T174-Y178 PolarHBondContact O-N 2.95Å; S176-Y178 VanDerWaalsContact C-N 3.28Å; S176-Y178 PolarHBondContact O-N 3.44Å; Y178-N180 PolarHBondContact O-N 3.41Å; Y178-N180 VanDerWaalsContact O-N 3.1Å; Y178-R181 HydrophobicContact CD1-CG 3.83Å; Y178-R181 VanDerWaalsContact CE1-NE 3.28Å; Y178-R181 PolarHBondContact O-N 3.43Å; Y178-P182 WeakPolarHBondContact O-CD 3.4Å
179	H	59.8	Low	73.7	Confident	112 Å²	112	69.6 Å²	69.6	52%	0.519	34%	0.336	S	S	.	.	T	Hydrogen-bonded Turn	trans	-54.5	-34.3	-176	-163.9	71.9	0	0	0	114.1	A175 P182	A175-H179 PolarHBondContact O-N 2.9Å; H179-P182 WeakPolarHBondContact O-CD 3.5Å
180	N	62.3	Low	75.4	Confident	99 Å²	99	63.7 Å²	63.7	53%	0.529	31%	0.31	S	S	.	.	T	Hydrogen-bonded Turn	trans	-92.8	-16.7	-177	-73.6	-23.8	0	0	0	115.4	Y178 K183	Y178-N180 PolarHBondContact O-N 3.41Å; Y178-N180 VanDerWaalsContact O-N 3.1Å; N180-K183 PolarHBondContact O-N 3.18Å
181	R	70.7	Confident	77.1	Confident	97 Å²	97	61.7 Å²	61.7	37%	0.366	30%	0.304	S	S	.	.	H	α-helix	trans	-60.2	-40.4	178.4	-74.2	-162.2	178.5	-177	4	114.7	Y178 K183 W184	Y178-R181 HydrophobicContact CD1-CG 3.83Å; Y178-R181 VanDerWaalsContact CE1-NE 3.28Å; Y178-R181 PolarHBondContact O-N 3.43Å; R181-K183 PolarHBondContact O-N 3.46Å; R181-W184 PolarHBondContact O-N 3.38Å; R181-W184 VanDerWaalsContact O-N 3.09Å
182	P	72.6	Confident	78.8	Confident	23 Å²	23	61.2 Å²	61.2	15%	0.149	30%	0.301	C	S	.	.	H	α-helix	trans	-61.9	-30.3	-179.8	19.6	-29.9	0	0	0	113	Y178 H179 W184 F185 I186	Y178-P182 WeakPolarHBondContact O-CD 3.4Å; H179-P182 WeakPolarHBondContact O-CD 3.5Å; P182-W184 VanDerWaalsContact C-N 3.28Å; P182-W184 PolarHBondContact O-N 2.89Å; P182-F185 HydrophobicContact CB-CD1 4.29Å; P182-F185 HydrophobicContact CB-CE1 3.93Å; P182-F185 WeakPolarHBondContact O-CD1 3.33Å; P182-F185 WeakPolarHBondContact O-CE1 3.42Å; P182-I186 WeakPolarHBondContact O-CD1 3.45Å; P182-I186 VanDerWaalsContact O-CG1 3.27Å; P182-I186 WeakPolarHBondContact O-CG1 3.39Å; P182-I186 PolarHBondContact O-N 3.44Å
183	K	89.9	Confident	80.4	Confident	90 Å²	90	57.6 Å²	57.6	39%	0.391	29%	0.287	S	S	.	.	H	α-helix	trans	-64.4	-34.4	177	-62.2	-178.7	-178.3	175	0	112.1	N180 R181 I186 F187 I251 I255	N180-K183 PolarHBondContact O-N 3.18Å; R181-K183 PolarHBondContact O-N 3.46Å; K183-I186 PolarHBondContact O-N 3.48Å; K183-F187 WeakPolarHBondContact O-CB 3.12Å; K183-F187 PolarHBondContact O-N 2.78Å; K183-I251 HydrophobicContact CG-CG2 4.44Å; K183-I255 HydrophobicContact CB-CD1 4.09Å; K183-I255 HydrophobicContact CG-CD1 4.45Å
184	W	92.4	Very high	82	Confident	137 Å²	137	53.2 Å²	53.2	52%	0.519	26%	0.263	S	S	.	.	H	α-helix	trans	-68.4	-43.7	179.9	-79.4	109	0	0	0	113.2	Y157 R181 P182 I186 F187 I188	Y157-W184 HydrophobicContact CD1-CB 4.01Å; Y157-W184 HydrophobicContact CD2-CB 4.39Å; Y157-W184 HydrophobicContact CE1-CB 4.48Å; Y157-W184 HydrophobicContact CG-CB 3.95Å; R181-W184 PolarHBondContact O-N 3.38Å; R181-W184 VanDerWaalsContact O-N 3.09Å; P182-W184 VanDerWaalsContact C-N 3.28Å; P182-W184 PolarHBondContact O-N 2.89Å; W184-I186 VanDerWaalsContact C-N 3.3Å; W184-I186 PolarHBondContact O-N 2.98Å; W184-F187 HydrophobicContact CE3-CD1 4.11Å; W184-F187 HydrophobicContact CZ3-CD1 4.05Å; W184-F187 HydrophobicContact CZ3-CE1 4.33Å; W184-F187 PolarHBondContact O-N 2.91Å; W184-I188 WeakPolarHBondContact O-CB 3.22Å; W184-I188 WeakPolarHBondContact O-CD1 3.23Å; W184-I188 VanDerWaalsContact O-CG1 3.25Å; W184-I188 WeakPolarHBondContact O-CG1 3.47Å; W184-I188 PolarHBondContact O-N 3.46Å
185	F	94.7	Very high	83.6	Confident	0 Å²	0	53.1 Å²	53.1	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-67.2	-35.1	177.2	92.2	-95.1	0	0	0	111.4	G154 Y158 P159 P182 I188 A189 W203 H210 Y252	G154-F185 WeakPolarHBondContact O-CB 3.5Å; Y158-F185 HydrophobicContact CD2-CD1 4.42Å; Y158-F185 AromaticContact CD2-CD2 3.86Å; Y158-F185 HydrophobicContact CD2-CD2 3.86Å; Y158-F185 HydrophobicContact CD2-CE1 4.44Å; Y158-F185 AromaticContact CD2-CE2 3.87Å; Y158-F185 HydrophobicContact CD2-CE2 3.87Å; Y158-F185 HydrophobicContact CD2-CG 4.16Å; Y158-F185 HydrophobicContact CD2-CZ 4.17Å; Y158-F185 HydrophobicContact CE2-CE2 4.13Å; Y158-F185 HydrophobicContact CE2-CZ 4.35Å; P159-F185 HydrophobicContact CG-CE1 4.11Å; P182-F185 HydrophobicContact CB-CD1 4.29Å; P182-F185 HydrophobicContact CB-CE1 3.93Å; P182-F185 WeakPolarHBondContact O-CD1 3.33Å; P182-F185 WeakPolarHBondContact O-CE1 3.42Å; F185-I188 PolarHBondContact O-N 2.9Å; F185-A189 VanDerWaalsContact O-CB 3.22Å; F185-A189 WeakPolarHBondContact O-CB 3.07Å; F185-A189 PolarHBondContact O-N 2.92Å; F185-W203 HydrophobicContact CD2-CE3 4.49Å; F185-W203 AromaticContact CD2-CZ3 3.98Å; F185-W203 HydrophobicContact CD2-CZ3 3.98Å; F185-H210 AromaticContact CE1-CE1 3.97Å; F185-H210 AromaticContact CE1-ND1 3.93Å; F185-H210 HydrophobicContact CZ-CB 4.15Å; F185-H210 AromaticContact CZ-CG 3.75Å; F185-H210 AromaticContact CZ-ND1 3.51Å; F185-Y252 WeakPolarHBondContact CZ-OH 3.22Å
186	I	96.2	Very high	85.1	Confident	3 Å²	3	52.3 Å²	52.3	2%	0.015	25%	0.253	C	S	.	.	H	α-helix	trans	-62.6	-48.8	175.5	-61.9	165.2	0	0	0	109.5	P182 K183 W184 I188 A189 V190 I251 Y252 I255	P182-I186 WeakPolarHBondContact O-CD1 3.45Å; P182-I186 VanDerWaalsContact O-CG1 3.27Å; P182-I186 WeakPolarHBondContact O-CG1 3.39Å; P182-I186 PolarHBondContact O-N 3.44Å; K183-I186 PolarHBondContact O-N 3.48Å; W184-I186 VanDerWaalsContact C-N 3.3Å; W184-I186 PolarHBondContact O-N 2.98Å; I186-I188 PolarHBondContact O-N 3.08Å; I186-A189 WeakPolarHBondContact O-CB 3.24Å; I186-A189 PolarHBondContact O-N 3.23Å; I186-V190 HydrophobicContact CG2-CG2 4.49Å; I186-V190 VanDerWaalsContact O-CG2 3.32Å; I186-V190 WeakPolarHBondContact O-CG2 3.31Å; I186-V190 PolarHBondContact O-N 3.11Å; I186-I251 HydrophobicContact CD1-CG2 4.2Å; I186-Y252 HydrophobicContact CD1-CD1 4.32Å; I186-Y252 HydrophobicContact CD1-CD2 3.77Å; I186-Y252 HydrophobicContact CD1-CE1 4.04Å; I186-Y252 HydrophobicContact CD1-CE2 3.48Å; I186-Y252 VanDerWaalsContact CD1-CE2 3.48Å; I186-Y252 HydrophobicContact CD1-CG 4.22Å; I186-Y252 HydrophobicContact CG1-CD1 4.28Å; I186-Y252 HydrophobicContact CG1-CE1 3.77Å; I186-Y252 HydrophobicContact CG1-CE2 4.09Å; I186-Y252 HydrophobicContact CG2-CD1 3.83Å; I186-Y252 HydrophobicContact CG2-CE1 4.06Å; I186-Y252 HydrophobicContact CG2-CG 4.3Å; I186-I255 HydrophobicContact CB-CD1 3.95Å; I186-I255 HydrophobicContact CD1-CD1 4.48Å; I186-I255 HydrophobicContact CG2-CB 4.17Å; I186-I255 HydrophobicContact CG2-CD1 3.82Å; I186-I255 HydrophobicContact CG2-CG2 4.16Å
187	F	97.1	Very high	86.8	Confident	87 Å²	87	49.4 Å²	49.4	38%	0.382	23%	0.232	S	C	.	.	H	α-helix	trans	-56.4	-48.6	176.2	174.7	-103.4	0	0	0	111.9	K183 W184 A189 V190 V191 I255	K183-F187 WeakPolarHBondContact O-CB 3.12Å; K183-F187 PolarHBondContact O-N 2.78Å; W184-F187 HydrophobicContact CE3-CD1 4.11Å; W184-F187 HydrophobicContact CZ3-CD1 4.05Å; W184-F187 HydrophobicContact CZ3-CE1 4.33Å; W184-F187 PolarHBondContact O-N 2.91Å; F187-A189 VanDerWaalsContact C-N 3.34Å; F187-A189 PolarHBondContact O-N 3.01Å; F187-V190 PolarHBondContact O-N 3.32Å; F187-V191 HydrophobicContact CD1-CG2 4.38Å; F187-V191 HydrophobicContact CD2-CG2 4.31Å; F187-V191 HydrophobicContact CE1-CG2 3.97Å; F187-V191 HydrophobicContact CE2-CG2 3.9Å; F187-V191 HydrophobicContact CZ-CG2 3.71Å; F187-V191 WeakPolarHBondContact O-CG2 3.4Å; F187-V191 PolarHBondContact O-N 2.84Å; F187-I255 HydrophobicContact CB-CG2 4.06Å; F187-I255 HydrophobicContact CD2-CG2 4.25Å
188	I	97.4	Very high	88.4	Confident	12 Å²	12	44.5 Å²	44.5	6%	0.062	21%	0.206	C	C	.	.	H	α-helix	trans	-63.4	-40.6	178.8	-67.1	161	0	0	0	111.5	L150 I153 Y157 W184 F185 I186 V190 V191 S192	L150-I188 HydrophobicContact CB-CG2 4.04Å; L150-I188 HydrophobicContact CD2-CG2 4.15Å; L150-I188 WeakPolarHBondContact O-CG2 3.48Å; I153-I188 HydrophobicContact CG2-CD1 3.74Å; Y157-I188 HydrophobicContact CD2-CD1 3.65Å; Y157-I188 HydrophobicContact CE2-CD1 4.15Å; W184-I188 WeakPolarHBondContact O-CB 3.22Å; W184-I188 WeakPolarHBondContact O-CD1 3.23Å; W184-I188 VanDerWaalsContact O-CG1 3.25Å; W184-I188 WeakPolarHBondContact O-CG1 3.47Å; W184-I188 PolarHBondContact O-N 3.46Å; F185-I188 PolarHBondContact O-N 2.9Å; I186-I188 PolarHBondContact O-N 3.08Å; I188-V190 VanDerWaalsContact C-N 3.34Å; I188-V190 PolarHBondContact O-N 3.38Å; I188-V191 PolarHBondContact O-N 3.4Å; I188-S192 VanDerWaalsContact O-CB 3.3Å; I188-S192 WeakPolarHBondContact O-CB 3.4Å; I188-S192 PolarHBondContact O-N 2.9Å
189	A	97.6	Very high	90	Very high	4 Å²	4	39.6 Å²	39.6	3%	0.033	19%	0.188	C	C	.	.	H	α-helix	trans	-59.6	-45.8	175.8	0	0	0	0	0	111.4	F185 I186 F187 S192 V193 W203	F185-A189 VanDerWaalsContact O-CB 3.22Å; F185-A189 WeakPolarHBondContact O-CB 3.07Å; F185-A189 PolarHBondContact O-N 2.92Å; I186-A189 WeakPolarHBondContact O-CB 3.24Å; I186-A189 PolarHBondContact O-N 3.23Å; F187-A189 VanDerWaalsContact C-N 3.34Å; F187-A189 PolarHBondContact O-N 3.01Å; A189-S192 WeakPolarHBondContact O-CB 3.23Å; A189-S192 PolarHBondContact O-N 3.35Å; A189-V193 WeakPolarHBondContact O-CG2 3.08Å; A189-V193 PolarHBondContact O-N 3.46Å; A189-W203 HydrophobicContact CB-CB 4Å; A189-W203 HydrophobicContact CB-CD2 3.33Å; A189-W203 HydrophobicContact CB-CE3 3.55Å; A189-W203 HydrophobicContact CB-CG 3.52Å; A189-W203 HydrophobicContact CB-CZ2 4.44Å; A189-W203 HydrophobicContact CB-CZ3 4.23Å
190	V	97.4	Very high	91.7	Very high	18 Å²	18	38.1 Å²	38.1	11%	0.109	18%	0.183	C	C	.	.	H	α-helix	trans	-63.7	-49.1	177.2	175.5	0	0	0	0	110.8	I186 F187 I188 S192 V193 L194 I256 C259	I186-V190 HydrophobicContact CG2-CG2 4.49Å; I186-V190 VanDerWaalsContact O-CG2 3.32Å; I186-V190 WeakPolarHBondContact O-CG2 3.31Å; I186-V190 PolarHBondContact O-N 3.11Å; F187-V190 PolarHBondContact O-N 3.32Å; I188-V190 VanDerWaalsContact C-N 3.34Å; I188-V190 PolarHBondContact O-N 3.38Å; V190-S192 VanDerWaalsContact C-N 3.26Å; V190-S192 PolarHBondContact O-N 3.49Å; V190-V193 PolarHBondContact O-N 3.42Å; V190-V193 VanDerWaalsContact O-N 3.11Å; V190-L194 HydrophobicContact CG1-CD1 3.99Å; V190-L194 HydrophobicContact CG1-CG 4.22Å; V190-L194 WeakPolarHBondContact O-CG 3.32Å; V190-L194 PolarHBondContact O-N 3.45Å; V190-I256 HydrophobicContact CG2-CB 4.49Å; V190-I256 HydrophobicContact CG2-CG1 3.56Å; V190-C259 HydrophobicContact CG1-CB 3.54Å
191	V	97.1	Very high	93.3	Very high	33 Å²	33	35.2 Å²	35.2	20%	0.2	17%	0.167	C	C	.	.	H	α-helix	trans	-58	-41.3	176.8	173	0	0	0	0	111.1	L150 F187 I188 V193 L194 I195	L150-V191 HydrophobicContact CD1-CG1 4Å; F187-V191 HydrophobicContact CD1-CG2 4.38Å; F187-V191 HydrophobicContact CD2-CG2 4.31Å; F187-V191 HydrophobicContact CE1-CG2 3.97Å; F187-V191 HydrophobicContact CE2-CG2 3.9Å; F187-V191 HydrophobicContact CZ-CG2 3.71Å; F187-V191 WeakPolarHBondContact O-CG2 3.4Å; F187-V191 PolarHBondContact O-N 2.84Å; I188-V191 PolarHBondContact O-N 3.4Å; V191-V193 PolarHBondContact O-N 2.88Å; V191-L194 PolarHBondContact O-N 3.28Å; V191-I195 HydrophobicContact CG1-CD1 3.94Å; V191-I195 WeakPolarHBondContact O-CG1 3.42Å; V191-I195 PolarHBondContact O-N 2.94Å
192	S	97.4	Very high	94.5	Very high	0 Å²	0	31 Å²	31	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-61.4	-42.7	176.6	-167.2	0	0	0	0	111.9	I188 A189 V190 R196 A199	I188-S192 VanDerWaalsContact O-CB 3.3Å; I188-S192 WeakPolarHBondContact O-CB 3.4Å; I188-S192 PolarHBondContact O-N 2.9Å; A189-S192 WeakPolarHBondContact O-CB 3.23Å; A189-S192 PolarHBondContact O-N 3.35Å; V190-S192 VanDerWaalsContact C-N 3.26Å; V190-S192 PolarHBondContact O-N 3.49Å; S192-R196 PolarHBondContact O-N 3.28Å; S192-R196 VanDerWaalsContact O-O 3.12Å; S192-A199 VanDerWaalsContact OG-CB 3.25Å; S192-A199 WeakPolarHBondContact OG-CB 3.17Å
193	V	97.1	Very high	95.7	Very high	32 Å²	32	30.1 Å²	30.1	19%	0.194	15%	0.145	C	C	.	.	H	α-helix	trans	-68.4	-37.3	176.8	172.9	0	0	0	0	111.7	A189 V190 V191 I195 R196 P197 A199 L200	A189-V193 WeakPolarHBondContact O-CG2 3.08Å; A189-V193 PolarHBondContact O-N 3.46Å; V190-V193 PolarHBondContact O-N 3.42Å; V190-V193 VanDerWaalsContact O-N 3.11Å; V191-V193 PolarHBondContact O-N 2.88Å; V193-I195 VanDerWaalsContact C-N 3.35Å; V193-R196 WeakPolarHBondContact CA-O 3.19Å; V193-R196 CarbonylContact O-C 3.05Å; V193-R196 PolarHBondContact O-N 2.92Å; V193-P197 WeakPolarHBondContact O-CA 3.39Å; V193-P197 VanDerWaalsContact O-N 3.13Å; V193-A199 HydrophobicContact CG2-CB 4.2Å; V193-L200 HydrophobicContact CG1-CD1 4.22Å; V193-L200 HydrophobicContact CG2-CB 4.2Å
194	L	96	Very high	96	Very high	15 Å²	15	32 Å²	32	8%	0.079	15%	0.154	C	C	.	.	H	α-helix	trans	-67.3	-35	177.6	-70.5	177.4	0	0	0	112.6	S64 V190 V191 C259 F260 Q278	S64-L194 WeakPolarHBondContact CB-O 3.5Å; S64-L194 PolarHBondContact OG-O 2.96Å; V190-L194 HydrophobicContact CG1-CD1 3.99Å; V190-L194 HydrophobicContact CG1-CG 4.22Å; V190-L194 WeakPolarHBondContact O-CG 3.32Å; V190-L194 PolarHBondContact O-N 3.45Å; V191-L194 PolarHBondContact O-N 3.28Å; L194-C259 HydrophobicContact CD1-CB 3.85Å; L194-C259 WeakPolarHBondContact CD1-O 3.4Å; L194-F260 HydrophobicContact CD2-CD2 3.78Å; L194-F260 HydrophobicContact CD2-CE2 4.38Å; L194-Q278 PolarHBondContact O-NE2 2.92Å; L194-Q278 VanDerWaalsContact O-NE2 3.1Å
195	I	95.5	Very high	96.2	Very high	14 Å²	14	27.5 Å²	27.5	7%	0.072	14%	0.142	C	C	.	.	H	α-helix	trans	-75.8	-44.7	173.6	-64.6	172	0	0	0	110.2	V66 H67 I146 L150 V191 V193	V66-I195 HydrophobicContact CB-CG1 4.11Å; V66-I195 HydrophobicContact CG1-CD1 4.12Å; V66-I195 HydrophobicContact CG1-CG1 3.77Å; H67-I195 HydrophobicContact CB-CG2 4.05Å; I146-I195 HydrophobicContact CG2-CD1 3.85Å; L150-I195 HydrophobicContact CD1-CD1 3.79Å; V191-I195 HydrophobicContact CG1-CD1 3.94Å; V191-I195 WeakPolarHBondContact O-CG1 3.42Å; V191-I195 PolarHBondContact O-N 2.94Å; V193-I195 VanDerWaalsContact C-N 3.35Å
196	R	94.7	Very high	96.2	Very high	14 Å²	14	27.6 Å²	27.6	5%	0.053	14%	0.142	C	C	.	.			trans	-138.1	111.3	177.5	-66	-162.2	66.5	106.9	-5	111.3	S143 N144 E147 S192 V193 T198 A199	S143-R196 PolarHBondContact OG-NH1 3.4Å; N144-R196 VanDerWaalsContact CG-CZ 3.44Å; N144-R196 PolarHBondContact ND2-NE 2.82Å; N144-R196 VanDerWaalsContact ND2-NE 3.19Å; N144-R196 PolarHBondContact ND2-NH2 3.42Å; N144-R196 VanDerWaalsContact OD1-CZ 3.25Å; N144-R196 PolarHBondContact OD1-NH1 3.31Å; E147-R196 HydrophobicContact CB-CG 4.49Å; E147-R196 WeakPolarHBondContact OE2-CD 3.46Å; E147-R196 IonicContact OE2-NE 2.88Å; S192-R196 PolarHBondContact O-N 3.28Å; S192-R196 VanDerWaalsContact O-O 3.12Å; V193-R196 WeakPolarHBondContact CA-O 3.19Å; V193-R196 CarbonylContact O-C 3.05Å; V193-R196 PolarHBondContact O-N 2.92Å; R196-T198 PolarHBondContact O-N 3.19Å; R196-A199 VanDerWaalsContact O-CB 3.28Å; R196-A199 WeakPolarHBondContact O-CB 3.35Å; R196-A199 PolarHBondContact O-N 3.4Å
197	P	94.5	Very high	96.2	Very high	18 Å²	18	28.4 Å²	28.4	12%	0.117	15%	0.148	C	C	.	.	G	3₁₀ helix	trans	-56.6	-24.4	176.7	-28.6	36.6	0	0	0	113.7	V193 A199 L200 Q278 F281	V193-P197 WeakPolarHBondContact O-CA 3.39Å; V193-P197 VanDerWaalsContact O-N 3.13Å; P197-A199 PolarHBondContact O-N 2.79Å; P197-L200 WeakPolarHBondContact O-CB 3.3Å; P197-L200 PolarHBondContact O-N 3.45Å; P197-L200 VanDerWaalsContact O-N 3.12Å; P197-Q278 HydrophobicContact CG-CB 3.82Å; P197-Q278 HydrophobicContact CG-CG 3.77Å; P197-F281 HydrophobicContact CB-CD1 3.69Å; P197-F281 HydrophobicContact CB-CE1 4.13Å; P197-F281 HydrophobicContact CB-CG 4.4Å; P197-F281 HydrophobicContact CG-CB 4.05Å; P197-F281 HydrophobicContact CG-CD1 3.72Å; P197-F281 HydrophobicContact CG-CE1 4.42Å; P197-F281 HydrophobicContact CG-CG 3.92Å
198	T	93	Very high	96.1	Very high	23 Å²	23	30 Å²	30	14%	0.141	16%	0.155	C	C	.	.	G	3₁₀ helix	trans	-62.2	-25.2	176.1	56.4	0	0	0	0	113.7	E147 R196 L200 I201 F281 Y372	E147-T198 PolarHBondContact OE1-OG1 3.24Å; E147-T198 VanDerWaalsContact OE1-OG1 3.06Å; R196-T198 PolarHBondContact O-N 3.19Å; T198-L200 PolarHBondContact O-N 3.47Å; T198-I201 WeakPolarHBondContact O-CB 3.35Å; T198-I201 WeakPolarHBondContact O-CG1 3.22Å; T198-I201 PolarHBondContact O-N 2.96Å; T198-F281 HydrophobicContact CG2-CE1 3.9Å; T198-F281 HydrophobicContact CG2-CZ 3.84Å; T198-Y372 VanDerWaalsContact CB-OH 3.31Å; T198-Y372 WeakPolarHBondContact CB-OH 3.45Å
199	A	96.5	Very high	96	Very high	1 Å²	1	31.7 Å²	31.7	1%	0.008	16%	0.161	C	C	.	.	G	3₁₀ helix	trans	-62.9	-14.6	175.4	0	0	0	0	0	112.7	E147 S192 V193 R196 P197 I201 I202 W203	E147-A199 HydrophobicContact CG-CB 4.22Å; E147-A199 WeakPolarHBondContact OE1-CA 3.41Å; E147-A199 PolarHBondContact OE1-N 2.98Å; S192-A199 VanDerWaalsContact OG-CB 3.25Å; S192-A199 WeakPolarHBondContact OG-CB 3.17Å; V193-A199 HydrophobicContact CG2-CB 4.2Å; R196-A199 VanDerWaalsContact O-CB 3.28Å; R196-A199 WeakPolarHBondContact O-CB 3.35Å; R196-A199 PolarHBondContact O-N 3.4Å; P197-A199 PolarHBondContact O-N 2.79Å; A199-I201 PolarHBondContact O-N 3.3Å; A199-I202 WeakPolarHBondContact O-CG2 3.49Å; A199-I202 PolarHBondContact O-N 3.03Å; A199-W203 VanDerWaalsContact O-CD1 3.27Å; A199-W203 PolarHBondContact O-N 3.22Å; A199-W203 VanDerWaalsContact O-N 3.08Å
200	L	96	Very high	95.7	Very high	81 Å²	81	31.5 Å²	31.5	42%	0.424	16%	0.159	S	C	.	.	H	α-helix	trans	-61.2	-28.5	174.1	-154.8	150.7	0	0	0	111.2	V193 P197 T198 I202 W203 F204	V193-L200 HydrophobicContact CG1-CD1 4.22Å; V193-L200 HydrophobicContact CG2-CB 4.2Å; P197-L200 WeakPolarHBondContact O-CB 3.3Å; P197-L200 PolarHBondContact O-N 3.45Å; P197-L200 VanDerWaalsContact O-N 3.12Å; T198-L200 PolarHBondContact O-N 3.47Å; L200-I202 VanDerWaalsContact C-N 3.34Å; L200-I202 PolarHBondContact O-N 3.47Å; L200-W203 PolarHBondContact O-N 3.04Å; L200-F204 HydrophobicContact CD2-CB 3.66Å; L200-F204 HydrophobicContact CD2-CD2 4.19Å; L200-F204 HydrophobicContact CD2-CG 4.1Å; L200-F204 HydrophobicContact CG-CB 4.38Å; L200-F204 WeakPolarHBondContact O-CB 3.47Å; L200-F204 PolarHBondContact O-N 3.44Å
201	I	95.9	Very high	95.5	Very high	38 Å²	38	32 Å²	32	20%	0.195	16%	0.161	C	C	.	.	H	α-helix	trans	-56.5	-45.9	175.6	-67.6	169.6	0	0	0	111.2	T198 A199 P205 W367 I368 C371 Y372	T198-I201 WeakPolarHBondContact O-CB 3.35Å; T198-I201 WeakPolarHBondContact O-CG1 3.22Å; T198-I201 PolarHBondContact O-N 2.96Å; A199-I201 PolarHBondContact O-N 3.3Å; I201-P205 WeakPolarHBondContact O-CD 3.43Å; I201-P205 WeakPolarHBondContact O-CG 3.24Å; I201-W367 VanDerWaalsContact O-CD1 3.24Å; I201-W367 PolarHBondContact O-NE1 3.09Å; I201-I368 HydrophobicContact CG2-CG1 4.38Å; I201-C371 HydrophobicContact CD1-CB 4.1Å; I201-C371 HydrophobicContact CG1-CB 4.37Å; I201-C371 HydrophobicContact CG2-CB 3.75Å; I201-Y372 HydrophobicContact CD1-CD1 4.49Å; I201-Y372 HydrophobicContact CD1-CD2 4.24Å; I201-Y372 HydrophobicContact CD1-CE1 4Å; I201-Y372 HydrophobicContact CD1-CE2 3.77Å
202	I	96.6	Very high	95.2	Very high	7 Å²	7	35.9 Å²	35.9	4%	0.036	17%	0.172	C	C	.	.	H	α-helix	trans	-81.5	-43.1	179.5	-173.5	175.3	0	0	0	111.7	C151 A199 L200 P205 L206 V364 I368	C151-I202 WeakPolarHBondContact SG-CD1 3.38Å; A199-I202 WeakPolarHBondContact O-CG2 3.49Å; A199-I202 PolarHBondContact O-N 3.03Å; L200-I202 VanDerWaalsContact C-N 3.34Å; L200-I202 PolarHBondContact O-N 3.47Å; I202-P205 WeakPolarHBondContact O-CD 3.28Å; I202-P205 WeakPolarHBondContact O-CG 3.3Å; I202-L206 HydrophobicContact CG1-CD1 3.96Å; I202-L206 WeakPolarHBondContact O-CG 3.43Å; I202-V364 HydrophobicContact CD1-CG1 4.05Å; I202-V364 HydrophobicContact CG1-CG1 3.82Å; I202-I368 HydrophobicContact CB-CD1 4.31Å; I202-I368 HydrophobicContact CD1-CD1 4.09Å; I202-I368 HydrophobicContact CG1-CD1 4.25Å
203	W	97.4	Very high	94.7	Very high	5 Å²	5	37 Å²	37	2%	0.019	18%	0.176	C	C	.	.	H	α-helix	trans	-79.2	-33.5	-169.2	-73.2	118.9	0	0	0	113.8	L155 F185 A189 A199 L200 L206 C207	L155-W203 HydrophobicContact CG-CH2 4.48Å; F185-W203 HydrophobicContact CD2-CE3 4.49Å; F185-W203 AromaticContact CD2-CZ3 3.98Å; F185-W203 HydrophobicContact CD2-CZ3 3.98Å; A189-W203 HydrophobicContact CB-CB 4Å; A189-W203 HydrophobicContact CB-CD2 3.33Å; A189-W203 HydrophobicContact CB-CE3 3.55Å; A189-W203 HydrophobicContact CB-CG 3.52Å; A189-W203 HydrophobicContact CB-CZ2 4.44Å; A189-W203 HydrophobicContact CB-CZ3 4.23Å; A199-W203 VanDerWaalsContact O-CD1 3.27Å; A199-W203 PolarHBondContact O-N 3.22Å; A199-W203 VanDerWaalsContact O-N 3.08Å; L200-W203 PolarHBondContact O-N 3.04Å; W203-L206 HydrophobicContact CE3-CD1 4.29Å; W203-L206 HydrophobicContact CZ3-CD1 4.26Å; W203-L206 PolarHBondContact O-N 3.42Å; W203-C207 WeakPolarHBondContact O-CB 3.3Å; W203-C207 PolarHBondContact O-N 3.22Å; W203-C207 PolarHBondContact O-SG 3.39Å
204	F	95.9	Very high	94.2	Very high	131 Å²	131	37.3 Å²	37.3	58%	0.575	18%	0.175	S	C	*	.	H	α-helix	trans	-58	-54.5	179.6	-178.1	-96.8	0	0	0	113.2	L200 L206 C207 F208	L200-F204 HydrophobicContact CD2-CB 3.66Å; L200-F204 HydrophobicContact CD2-CD2 4.19Å; L200-F204 HydrophobicContact CD2-CG 4.1Å; L200-F204 HydrophobicContact CG-CB 4.38Å; L200-F204 WeakPolarHBondContact O-CB 3.47Å; L200-F204 PolarHBondContact O-N 3.44Å; F204-L206 VanDerWaalsContact C-N 3.34Å; F204-L206 PolarHBondContact O-N 2.89Å; F204-C207 PolarHBondContact O-N 3.06Å; F204-F208 VanDerWaalsContact O-CB 3.32Å; F204-F208 WeakPolarHBondContact O-CB 3.49Å; F204-F208 PolarHBondContact O-N 2.84Å
205	P	96.2	Very high	93.8	Very high	41 Å²	41	36.6 Å²	36.6	27%	0.266	17%	0.171	S	C	.	.	H	α-helix	trans	-64.9	-36.1	179	25.4	-34.8	0	0	0	112.7	I201 I202 W209	I201-P205 WeakPolarHBondContact O-CD 3.43Å; I201-P205 WeakPolarHBondContact O-CG 3.24Å; I202-P205 WeakPolarHBondContact O-CD 3.28Å; I202-P205 WeakPolarHBondContact O-CG 3.3Å; P205-W209 VanDerWaalsContact O-CB 3.22Å; P205-W209 WeakPolarHBondContact O-CB 3.16Å; P205-W209 PolarHBondContact O-N 2.89Å
206	L	95.7	Very high	93.3	Very high	2 Å²	2	39.6 Å²	39.6	1%	0.01	19%	0.186	C	C	.	.	H	α-helix	trans	-67.7	-43.4	177.8	-71.1	178.2	0	0	0	112.3	L155 Y158 I202 W203 F204 W209 H210 L360 V364	L155-L206 HydrophobicContact CD2-CD1 3.7Å; Y158-L206 HydrophobicContact CE1-CD2 4.23Å; Y158-L206 HydrophobicContact CE2-CB 3.98Å; Y158-L206 HydrophobicContact CE2-CD2 4.45Å; Y158-L206 PolarHBondContact OH-O 2.94Å; Y158-L206 VanDerWaalsContact OH-O 3.14Å; I202-L206 HydrophobicContact CG1-CD1 3.96Å; I202-L206 WeakPolarHBondContact O-CG 3.43Å; W203-L206 HydrophobicContact CE3-CD1 4.29Å; W203-L206 HydrophobicContact CZ3-CD1 4.26Å; W203-L206 PolarHBondContact O-N 3.42Å; F204-L206 VanDerWaalsContact C-N 3.34Å; F204-L206 PolarHBondContact O-N 2.89Å; L206-W209 PolarHBondContact O-N 3.49Å; L206-H210 WeakPolarHBondContact O-CB 3.4Å; L206-H210 PolarHBondContact O-N 3.48Å; L206-L360 HydrophobicContact CD2-CD2 4.36Å; L206-V364 HydrophobicContact CD2-CG2 3.78Å; L206-V364 HydrophobicContact CG-CG2 4.3Å
207	C	95.9	Very high	92.6	Very high	20 Å²	20	39.8 Å²	39.8	14%	0.135	19%	0.188	C	C	.	.	H	α-helix	trans	-65.2	-44.3	175.9	-72.6	0	0	0	0	111.3	W203 F204 W209 H210 I211 Y252	W203-C207 WeakPolarHBondContact O-CB 3.3Å; W203-C207 PolarHBondContact O-N 3.22Å; W203-C207 PolarHBondContact O-SG 3.39Å; F204-C207 PolarHBondContact O-N 3.06Å; C207-W209 PolarHBondContact O-N 3.26Å; C207-H210 PolarHBondContact O-N 3.18Å; C207-I211 WeakPolarHBondContact O-CG1 3.24Å; C207-I211 PolarHBondContact O-N 3.18Å; C207-Y252 HydrophobicContact CB-CE1 3.74Å
208	F	95	Very high	91.8	Very high	120 Å²	120	39.7 Å²	39.7	53%	0.526	19%	0.188	S	C	.	.	H	α-helix	trans	-58.9	-47.4	174.7	-178.8	-96.5	0	0	0	111.2	F204 H210 I211 W212	F204-F208 VanDerWaalsContact O-CB 3.32Å; F204-F208 WeakPolarHBondContact O-CB 3.49Å; F204-F208 PolarHBondContact O-N 2.84Å; F208-H210 PolarHBondContact O-N 3.46Å; F208-I211 PolarHBondContact O-N 3.24Å; F208-W212 HydrophobicContact CZ-CE3 4.29Å; F208-W212 VanDerWaalsContact O-CB 3.29Å; F208-W212 WeakPolarHBondContact O-CB 3.36Å; F208-W212 PolarHBondContact O-N 3.23Å
209	W	93.7	Very high	91.1	Very high	48 Å²	48	39.1 Å²	39.1	18%	0.182	19%	0.185	C	C	.	.	H	α-helix	trans	-62.7	-40.6	178.2	-172.3	-116.9	0	0	0	112.5	I163 P205 L206 C207 W212 R213 F354	I163-W209 VanDerWaalsContact CG2-CD1 3.43Å; P205-W209 VanDerWaalsContact O-CB 3.22Å; P205-W209 WeakPolarHBondContact O-CB 3.16Å; P205-W209 PolarHBondContact O-N 2.89Å; L206-W209 PolarHBondContact O-N 3.49Å; C207-W209 PolarHBondContact O-N 3.26Å; W209-W212 PolarHBondContact O-N 2.95Å; W209-R213 HydrophobicContact CD2-CG 4.03Å; W209-R213 HydrophobicContact CG-CG 4.35Å; W209-R213 HydrophobicContact CZ2-CG 3.96Å; W209-R213 WeakPolarHBondContact O-CB 3.25Å; W209-R213 WeakPolarHBondContact O-CG 3.43Å; W209-R213 PolarHBondContact O-N 3.32Å; W209-F354 HydrophobicContact CH2-CB 3.91Å; W209-F354 HydrophobicContact CH2-CD1 4.22Å; W209-F354 HydrophobicContact CH2-CG 4.23Å; W209-F354 HydrophobicContact CZ2-CB 3.63Å; W209-F354 HydrophobicContact CZ2-CD1 4.29Å; W209-F354 HydrophobicContact CZ2-CG 4.31Å; W209-F354 HydrophobicContact CZ3-CD1 4.48Å
210	H	92.1	Very high	90.1	Very high	1 Å²	1	40.9 Å²	40.9	1%	0.005	20%	0.196	C	C	.	.	H	α-helix	trans	-60.4	-50.4	175.1	171.3	-114	0	0	0	112.1	Y158 P159 I163 F185 L206 C207 F208 R213 K214 Y252	Y158-H210 HydrophobicContact CE2-CB 4.22Å; P159-H210 WeakPolarHBondContact CG-CD2 3.43Å; I163-H210 HydrophobicContact CD1-CB 4.26Å; F185-H210 AromaticContact CE1-CE1 3.97Å; F185-H210 AromaticContact CE1-ND1 3.93Å; F185-H210 HydrophobicContact CZ-CB 4.15Å; F185-H210 AromaticContact CZ-CG 3.75Å; F185-H210 AromaticContact CZ-ND1 3.51Å; L206-H210 WeakPolarHBondContact O-CB 3.4Å; L206-H210 PolarHBondContact O-N 3.48Å; C207-H210 PolarHBondContact O-N 3.18Å; F208-H210 PolarHBondContact O-N 3.46Å; H210-R213 PolarHBondContact O-N 3.22Å; H210-K214 WeakPolarHBondContact O-CB 3.47Å; H210-K214 WeakPolarHBondContact O-CG 3.49Å; H210-K214 PolarHBondContact O-N 3.07Å; H210-Y252 AromaticContact ND1-CE2 3.9Å; H210-Y252 AromaticContact ND1-CZ 3.84Å; H210-Y252 PolarHBondContact ND1-OH 3.48Å
211	I	92.5	Very high	88.8	Confident	28 Å²	28	40 Å²	40	14%	0.144	19%	0.191	C	C	.	.	H	α-helix	trans	-59.6	-50.2	178.1	-66.5	168.7	0	0	0	109.6	C207 F208 R213 K214 C215 L245 Q248 Y252	C207-I211 WeakPolarHBondContact O-CG1 3.24Å; C207-I211 PolarHBondContact O-N 3.18Å; F208-I211 PolarHBondContact O-N 3.24Å; I211-R213 PolarHBondContact O-N 2.9Å; I211-K214 PolarHBondContact O-N 3.27Å; I211-C215 PolarHBondContact O-N 3.42Å; I211-C215 PolarHBondContact O-SG 3.49Å; I211-L245 HydrophobicContact CG2-CD1 3.46Å; I211-L245 VanDerWaalsContact CG2-CD1 3.46Å; I211-Q248 HydrophobicContact CG1-CB 4.35Å; I211-Q248 HydrophobicContact CG2-CB 4.15Å; I211-Y252 HydrophobicContact CD1-CD1 4.41Å; I211-Y252 HydrophobicContact CD1-CD2 3.99Å; I211-Y252 HydrophobicContact CD1-CE1 4.21Å; I211-Y252 HydrophobicContact CD1-CE2 3.75Å; I211-Y252 HydrophobicContact CD1-CG 4.29Å; I211-Y252 HydrophobicContact CG1-CD2 4.15Å; I211-Y252 HydrophobicContact CG1-CE2 3.52Å
212	W	91	Very high	87.2	Confident	115 Å²	115	40.6 Å²	40.6	44%	0.436	20%	0.195	S	C	.	.	H	α-helix	trans	-56	-48.4	179.7	-174.5	-96.8	0	0	0	112	F208 W209 C215 M216 F241	F208-W212 HydrophobicContact CZ-CE3 4.29Å; F208-W212 VanDerWaalsContact O-CB 3.29Å; F208-W212 WeakPolarHBondContact O-CB 3.36Å; F208-W212 PolarHBondContact O-N 3.23Å; W209-W212 PolarHBondContact O-N 2.95Å; W212-C215 PolarHBondContact O-N 3.45Å; W212-M216 WeakPolarHBondContact O-CB 3.5Å; W212-M216 VanDerWaalsContact O-CG 3.29Å; W212-M216 WeakPolarHBondContact O-CG 3.35Å; W212-M216 PolarHBondContact O-N 3.41Å; W212-F241 HydrophobicContact CE3-CZ 4.23Å; W212-F241 HydrophobicContact CZ3-CZ 4.1Å
213	R	87.6	Confident	85.3	Confident	24 Å²	24	47.4 Å²	47.4	9%	0.091	22%	0.224	C	C	.	.	H	α-helix	trans	-64.4	-43.3	-179.7	-73.1	-69.1	-68.7	145.4	1.5	112.3	I163 H165 W209 H210 I211 C215 M216 I217	I163-R213 HydrophobicContact CG2-CG 4.5Å; I163-R213 PolarHBondContact O-NE 2.93Å; I163-R213 PolarHBondContact O-NH2 2.91Å; I163-R213 VanDerWaalsContact O-NH2 3.16Å; H165-R213 PolarHBondContact O-NH2 3.4Å; H165-R213 VanDerWaalsContact O-NH2 3.11Å; W209-R213 HydrophobicContact CD2-CG 4.03Å; W209-R213 HydrophobicContact CG-CG 4.35Å; W209-R213 HydrophobicContact CZ2-CG 3.96Å; W209-R213 WeakPolarHBondContact O-CB 3.25Å; W209-R213 WeakPolarHBondContact O-CG 3.43Å; W209-R213 PolarHBondContact O-N 3.32Å; H210-R213 PolarHBondContact O-N 3.22Å; I211-R213 PolarHBondContact O-N 2.9Å; R213-C215 PolarHBondContact O-N 3.31Å; R213-M216 PolarHBondContact O-N 3.36Å; R213-I217 WeakPolarHBondContact O-CB 3.4Å; R213-I217 WeakPolarHBondContact O-CD1 3.48Å; R213-I217 VanDerWaalsContact O-CG1 3.24Å; R213-I217 WeakPolarHBondContact O-CG1 3.31Å; R213-I217 PolarHBondContact O-N 3.3Å
214	K	85.9	Confident	83.3	Confident	38 Å²	38	53.6 Å²	53.6	17%	0.165	26%	0.258	C	S	.	.	H	α-helix	trans	-59.7	-45.6	176.3	-79.7	-72.8	-167.2	177.7	0	111.7	V162 H210 I211 I217 A218 Q248	V162-K214 HydrophobicContact CG1-CD 4Å; H210-K214 WeakPolarHBondContact O-CB 3.47Å; H210-K214 WeakPolarHBondContact O-CG 3.49Å; H210-K214 PolarHBondContact O-N 3.07Å; I211-K214 PolarHBondContact O-N 3.27Å; K214-I217 PolarHBondContact O-N 2.9Å; K214-A218 WeakPolarHBondContact O-CB 3.33Å; K214-A218 PolarHBondContact O-N 2.91Å; K214-Q248 HydrophobicContact CB-CG 4.3Å
215	C	87.7	Confident	81.2	Confident	0 Å²	0	54.1 Å²	54.1	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-65.9	-42.4	179.2	-58.9	0	0	0	0	111.8	I211 W212 R213 A218 S219 F241 L245	I211-C215 PolarHBondContact O-N 3.42Å; I211-C215 PolarHBondContact O-SG 3.49Å; W212-C215 PolarHBondContact O-N 3.45Å; R213-C215 PolarHBondContact O-N 3.31Å; C215-A218 PolarHBondContact O-N 3.31Å; C215-S219 PolarHBondContact O-N 3.09Å; C215-F241 HydrophobicContact CB-CD2 3.51Å; C215-F241 HydrophobicContact CB-CE1 4.42Å; C215-F241 HydrophobicContact CB-CE2 3.3Å; C215-F241 HydrophobicContact CB-CG 4.17Å; C215-F241 HydrophobicContact CB-CZ 3.8Å; C215-L245 WeakPolarHBondContact SG-CA 3.36Å
216	M	84.6	Confident	79.2	Confident	77 Å²	77	58.6 Å²	58.6	38%	0.379	28%	0.282	S	S	.	.	H	α-helix	trans	-61.2	-46	175.4	-74.6	-64.8	-69.8	0	0	112	W212 R213 S219 T220 F241	W212-M216 WeakPolarHBondContact O-CB 3.5Å; W212-M216 VanDerWaalsContact O-CG 3.29Å; W212-M216 WeakPolarHBondContact O-CG 3.35Å; W212-M216 PolarHBondContact O-N 3.41Å; R213-M216 PolarHBondContact O-N 3.36Å; M216-S219 PolarHBondContact O-N 3.06Å; M216-S219 PolarHBondContact O-OG 3.34Å; M216-T220 WeakPolarHBondContact O-CG2 3.18Å; M216-T220 PolarHBondContact O-N 3.32Å; M216-F241 HydrophobicContact CG-CE2 4.2Å; M216-F241 HydrophobicContact SD-CD2 4.43Å; M216-F241 HydrophobicContact SD-CE2 4.04Å
217	I	80.2	Confident	77.2	Confident	18 Å²	18	67 Å²	67	9%	0.092	32%	0.321	C	S	.	.	H	α-helix	trans	-62.7	-46.4	178.6	-68.4	161.6	0	0	0	110.3	V162 I171 R213 K214 S219 T220 L221	V162-I217 HydrophobicContact CG1-CD1 4.02Å; V162-I217 WeakPolarHBondContact O-CD1 3.26Å; I171-I217 HydrophobicContact CD1-CD1 4.11Å; I171-I217 HydrophobicContact CG2-CD1 4.48Å; I171-I217 HydrophobicContact CG2-CG2 4.25Å; R213-I217 WeakPolarHBondContact O-CB 3.4Å; R213-I217 WeakPolarHBondContact O-CD1 3.48Å; R213-I217 VanDerWaalsContact O-CG1 3.24Å; R213-I217 WeakPolarHBondContact O-CG1 3.31Å; R213-I217 PolarHBondContact O-N 3.3Å; K214-I217 PolarHBondContact O-N 2.9Å; I217-S219 VanDerWaalsContact C-N 3.29Å; I217-S219 PolarHBondContact O-N 3.15Å; I217-T220 PolarHBondContact O-N 3.45Å; I217-T220 PolarHBondContact O-OG1 3.24Å; I217-L221 HydrophobicContact CG2-CD1 4.46Å; I217-L221 PolarHBondContact O-N 2.79Å
218	A	78.5	Confident	75.3	Confident	15 Å²	15	71.8 Å²	71.8	12%	0.124	35%	0.345	C	S	.	.	H	α-helix	trans	-57.1	-42	177.6	0	0	0	0	0	112.2	K214 C215 T220 L221 H244	K214-A218 WeakPolarHBondContact O-CB 3.33Å; K214-A218 PolarHBondContact O-N 2.91Å; C215-A218 PolarHBondContact O-N 3.31Å; A218-T220 PolarHBondContact O-N 2.89Å; A218-L221 PolarHBondContact O-N 2.94Å; A218-H244 HydrophobicContact CB-CB 3.99Å
219	S	78.8	Confident	73.6	Confident	11 Å²	11	72.8 Å²	72.8	8%	0.077	36%	0.355	C	S	.	.	H	α-helix	trans	-66.6	-15.7	177.3	77.1	0	0	0	0	114.8	C215 M216 I217	C215-S219 PolarHBondContact O-N 3.09Å; M216-S219 PolarHBondContact O-N 3.06Å; M216-S219 PolarHBondContact O-OG 3.34Å; I217-S219 VanDerWaalsContact C-N 3.29Å; I217-S219 PolarHBondContact O-N 3.15Å
220	T	75	Confident	72.2	Confident	39 Å²	39	78.9 Å²	78.9	24%	0.239	38%	0.383	C	S	.	.	H	α-helix	trans	-93.8	-21.3	179.5	57.1	0	0	0	0	114.2	Q168 M216 I217 A218 D222	Q168-T220 PolarHBondContact NE2-OG1 3.16Å; Q168-T220 VanDerWaalsContact NE2-OG1 3.15Å; M216-T220 WeakPolarHBondContact O-CG2 3.18Å; M216-T220 PolarHBondContact O-N 3.32Å; I217-T220 PolarHBondContact O-N 3.45Å; I217-T220 PolarHBondContact O-OG1 3.24Å; A218-T220 PolarHBondContact O-N 2.89Å; T220-D222 VanDerWaalsContact C-N 3.3Å; T220-D222 PolarHBondContact O-N 3.44Å
221	L	69.1	Low	70.8	Confident	61 Å²	61	86.9 Å²	86.9	32%	0.319	42%	0.42	S	S	.	.	G	3₁₀ helix	trans	-74	-17.1	-176.9	-72.4	171.4	0	0	0	113.7	Q168 Q172 I217 A218 K223	Q168-L221 HydrophobicContact CB-CD2 4.42Å; Q172-L221 VanDerWaalsContact NE2-CD2 3.28Å; I217-L221 HydrophobicContact CG2-CD1 4.46Å; I217-L221 PolarHBondContact O-N 2.79Å; A218-L221 PolarHBondContact O-N 2.94Å; L221-K223 PolarHBondContact O-N 3.08Å
222	D	62.2	Low	69.5	Low	52 Å²	52	91.6 Å²	91.6	28%	0.278	44%	0.437	S	S	.	.	G	3₁₀ helix	trans	-73	-8.6	178.9	-164.4	46	0	0	0	113.5	T220 D224 S236	T220-D222 VanDerWaalsContact C-N 3.3Å; T220-D222 PolarHBondContact O-N 3.44Å; D222-D224 PolarHBondContact O-N 3.38Å; D222-S236 PolarHBondContact OD2-OG 2.97Å
223	K	56.9	Low	68.2	Low	150 Å²	150	90.1 Å²	90.1	65%	0.652	44%	0.435	S	S	*	.	G	3₁₀ helix	trans	-61.3	-26.5	-177.6	-81.3	-168.7	171.7	-168.7	0	113.8	L221 N225	L221-K223 PolarHBondContact O-N 3.08Å; K223-N225 VanDerWaalsContact C-N 3.33Å; K223-N225 PolarHBondContact O-N 3Å
224	D	55	Low	67.2	Low	135 Å²	135	95.6 Å²	95.6	72%	0.722	46%	0.462	S	S	*	.	G	3₁₀ helix	trans	-81.3	-8.6	-169.3	-69.4	-18.5	0	0	0	114.1	D222	D222-D224 PolarHBondContact O-N 3.38Å
225	N	52.5	Low	66.6	Low	141 Å²	141	100.2 Å²	100.2	75%	0.754	48%	0.484	S	S	*	.	S	Bend	trans	-112.4	-12.8	-167.9	-95.1	-24.4	0	0	0	118.2	K223	K223-N225 VanDerWaalsContact C-N 3.33Å; K223-N225 PolarHBondContact O-N 3Å
226	K	53.3	Low	66.1	Low	135 Å²	135	101 Å²	101	59%	0.587	49%	0.489	S	S	*	.			trans	-147.6	120.5	-177	-68.2	-172.9	177.4	178.2	0	113.9	Y232	K226-Y232 HydrophobicContact CD-CE1 4.23Å
227	H	53.2	Low	65.8	Low	179 Å²	179	101.9 Å²	101.9	83%	0.829	49%	0.488	S	S	*	.			trans	-88.1	3.7	-171.9	-147.4	-72.9	0	0	0	114.8
228	D	56.5	Low	66	Low	120 Å²	120	105.2 Å²	105.2	64%	0.642	51%	0.509	S	S	*	.	S	Bend	trans	-118.5	126.7	-166.9	-60.2	-46.8	0	0	0	114
229	L	60.3	Low	66.4	Low	142 Å²	142	110.4 Å²	110.4	74%	0.743	53%	0.529	S	S	*	.			trans	65.5	116.8	168.5	-62.1	160.2	0	0	0	117.9	E231 Y232 Q233	L229-E231 VanDerWaalsContact C-N 3.3Å; L229-E231 PolarHBondContact O-N 3.5Å; L229-Y232 PolarHBondContact O-N 3.5Å; L229-Q233 WeakPolarHBondContact O-CG 3.44Å; L229-Q233 PolarHBondContact O-N 3.38Å; L229-Q233 VanDerWaalsContact O-N 3.16Å
230	K	64	Low	66.6	Low	175 Å²	175	116 Å²	116	76%	0.761	55%	0.549	S	S	*	.	H	α-helix	trans	-53.4	-39.5	178.4	-75.3	-176.9	178.1	177.2	0	113.8	Q233 E234	K230-Q233 WeakPolarHBondContact O-CB 3.27Å; K230-Q233 PolarHBondContact O-N 2.94Å; K230-E234 PolarHBondContact O-N 2.87Å
231	E	62.6	Low	67.2	Low	170 Å²	170	116.2 Å²	116.2	79%	0.794	55%	0.546	S	S	*	.	H	α-helix	trans	-67.8	-40.6	-178.4	-168.4	174.2	-176.2	0	0	111.9	L229 Q233 E234 H235	L229-E231 VanDerWaalsContact C-N 3.3Å; L229-E231 PolarHBondContact O-N 3.5Å; E231-Q233 VanDerWaalsContact C-N 3.28Å; E231-Q233 PolarHBondContact O-N 3.37Å; E231-E234 PolarHBondContact O-N 3.4Å; E231-H235 PolarHBondContact O-N 2.97Å; E231-H235 VanDerWaalsContact O-N 3.16Å
232	Y	64.1	Low	68.2	Low	127 Å²	127	116.4 Å²	116.4	50%	0.498	55%	0.55	S	S	.	.	H	α-helix	trans	-63.7	-36.3	173.4	-174.4	-93.3	0	0	0	111.4	K226 L229 S236	K226-Y232 HydrophobicContact CD-CE1 4.23Å; L229-Y232 PolarHBondContact O-N 3.5Å; Y232-S236 WeakPolarHBondContact O-CB 3.37Å; Y232-S236 PolarHBondContact O-N 3.48Å
233	Q	64	Low	69.5	Low	84 Å²	84	118 Å²	118	39%	0.393	56%	0.559	S	S	.	*	H	α-helix	trans	-65.6	-44.3	176.7	-67	175.5	-16.5	0	0	112.6	L229 K230 E231 S236 R237	L229-Q233 WeakPolarHBondContact O-CG 3.44Å; L229-Q233 PolarHBondContact O-N 3.38Å; L229-Q233 VanDerWaalsContact O-N 3.16Å; K230-Q233 WeakPolarHBondContact O-CB 3.27Å; K230-Q233 PolarHBondContact O-N 2.94Å; E231-Q233 VanDerWaalsContact C-N 3.28Å; E231-Q233 PolarHBondContact O-N 3.37Å; Q233-S236 PolarHBondContact O-N 2.97Å; Q233-R237 WeakPolarHBondContact O-CG 3.45Å; Q233-R237 PolarHBondContact O-N 3.32Å
234	E	67.4	Low	71	Confident	139 Å²	139	113 Å²	113	65%	0.65	54%	0.537	S	S	*	.	H	α-helix	trans	-66.2	-41.6	178.3	-73.4	-171.2	167.5	0	0	112.4	K230 E231 R237 T238	K230-E234 PolarHBondContact O-N 2.87Å; E231-E234 PolarHBondContact O-N 3.4Å; E234-R237 PolarHBondContact O-N 2.99Å; E234-T238 PolarHBondContact O-N 3.47Å; E234-T238 VanDerWaalsContact O-N 3.12Å; E234-T238 PolarHBondContact O-OG1 3.24Å
235	H	72.4	Confident	72.8	Confident	134 Å²	134	109.2 Å²	109.2	62%	0.62	52%	0.517	S	S	*	.	H	α-helix	trans	-63.6	-43.2	176.1	-168.1	77.3	0	0	0	111.7	E231 R237 T238 K239	E231-H235 PolarHBondContact O-N 2.97Å; E231-H235 VanDerWaalsContact O-N 3.16Å; H235-R237 PolarHBondContact O-N 3.48Å; H235-T238 PolarHBondContact O-N 2.92Å; H235-K239 WeakPolarHBondContact O-CB 3.36Å; H235-K239 PolarHBondContact O-N 3.39Å; H235-K239 VanDerWaalsContact O-N 3.07Å
236	S	76.9	Confident	74.7	Confident	16 Å²	16	107.6 Å²	107.6	11%	0.112	51%	0.507	C	S	.	.	H	α-helix	trans	-59.4	-47.6	176	-170.7	0	0	0	0	111.7	D222 Y232 Q233 T238 K239 W240	D222-S236 PolarHBondContact OD2-OG 2.97Å; Y232-S236 WeakPolarHBondContact O-CB 3.37Å; Y232-S236 PolarHBondContact O-N 3.48Å; Q233-S236 PolarHBondContact O-N 2.97Å; S236-T238 PolarHBondContact O-N 3.41Å; S236-K239 PolarHBondContact O-N 3.19Å; S236-W240 VanDerWaalsContact O-CD1 3.28Å; S236-W240 PolarHBondContact O-N 3.28Å
237	R	79.6	Confident	76.5	Confident	97 Å²	97	106.9 Å²	106.9	37%	0.366	50%	0.501	S	S	.	.	H	α-helix	trans	-60.5	-44	-179	-71.3	173.3	107.1	-166.4	1.7	112.5	Q233 E234 H235 W240 F241	Q233-R237 WeakPolarHBondContact O-CG 3.45Å; Q233-R237 PolarHBondContact O-N 3.32Å; E234-R237 PolarHBondContact O-N 2.99Å; H235-R237 PolarHBondContact O-N 3.48Å; R237-W240 PolarHBondContact O-N 3.41Å; R237-F241 WeakPolarHBondContact O-CB 3.31Å; R237-F241 PolarHBondContact O-N 3.43Å
238	T	84.9	Confident	78.4	Confident	87 Å²	87	98.9 Å²	98.9	53%	0.534	47%	0.465	S	S	.	.	H	α-helix	trans	-63.2	-45.4	178	-55.2	0	0	0	0	110.7	E234 H235 S236 W240 F241 V242	E234-T238 PolarHBondContact O-N 3.47Å; E234-T238 VanDerWaalsContact O-N 3.12Å; E234-T238 PolarHBondContact O-OG1 3.24Å; H235-T238 PolarHBondContact O-N 2.92Å; S236-T238 PolarHBondContact O-N 3.41Å; T238-W240 PolarHBondContact O-N 3.41Å; T238-F241 PolarHBondContact O-N 3.28Å; T238-V242 VanDerWaalsContact O-CG2 3.31Å; T238-V242 WeakPolarHBondContact O-CG2 3.38Å; T238-V242 PolarHBondContact O-N 3.44Å
239	K	86.2	Confident	80.2	Confident	125 Å²	125	96.7 Å²	96.7	54%	0.543	45%	0.452	S	S	.	.	H	α-helix	trans	-60.5	-44.6	177.5	-173.2	175.7	-178.1	175.9	0	112.3	H235 S236 V242 N243	H235-K239 WeakPolarHBondContact O-CB 3.36Å; H235-K239 PolarHBondContact O-N 3.39Å; H235-K239 VanDerWaalsContact O-N 3.07Å; S236-K239 PolarHBondContact O-N 3.19Å; K239-V242 PolarHBondContact O-N 3.24Å; K239-N243 WeakPolarHBondContact O-CB 3.49Å; K239-N243 VanDerWaalsContact O-CG 3.23Å; K239-N243 PolarHBondContact O-N 2.84Å; K239-N243 PolarHBondContact O-ND2 2.83Å
240	W	82.3	Confident	81.8	Confident	129 Å²	129	91.8 Å²	91.8	49%	0.489	44%	0.435	S	S	.	.	H	α-helix	trans	-65.4	-42.2	176.9	-87.2	100.1	0	0	0	112.9	S236 R237 T238 N243 H244	S236-W240 VanDerWaalsContact O-CD1 3.28Å; S236-W240 PolarHBondContact O-N 3.28Å; R237-W240 PolarHBondContact O-N 3.41Å; T238-W240 PolarHBondContact O-N 3.41Å; W240-N243 PolarHBondContact O-N 3.45Å; W240-H244 WeakPolarHBondContact O-CB 3.37Å; W240-H244 PolarHBondContact O-N 3.25Å
241	F	88.7	Confident	83.2	Confident	43 Å²	43	84.7 Å²	84.7	19%	0.189	41%	0.405	C	S	.	.	H	α-helix	trans	-58.1	-49.8	174.8	-178.5	-86.2	0	0	0	110.9	W212 C215 M216 R237 T238 H244 L245	W212-F241 HydrophobicContact CE3-CZ 4.23Å; W212-F241 HydrophobicContact CZ3-CZ 4.1Å; C215-F241 HydrophobicContact CB-CD2 3.51Å; C215-F241 HydrophobicContact CB-CE1 4.42Å; C215-F241 HydrophobicContact CB-CE2 3.3Å; C215-F241 HydrophobicContact CB-CG 4.17Å; C215-F241 HydrophobicContact CB-CZ 3.8Å; M216-F241 HydrophobicContact CG-CE2 4.2Å; M216-F241 HydrophobicContact SD-CD2 4.43Å; M216-F241 HydrophobicContact SD-CE2 4.04Å; R237-F241 WeakPolarHBondContact O-CB 3.31Å; R237-F241 PolarHBondContact O-N 3.43Å; T238-F241 PolarHBondContact O-N 3.28Å; F241-H244 PolarHBondContact O-N 2.94Å; F241-L245 HydrophobicContact CE1-CD2 4.28Å; F241-L245 VanDerWaalsContact O-CB 3.3Å; F241-L245 WeakPolarHBondContact O-CB 3.47Å; F241-L245 PolarHBondContact O-N 3.5Å
242	V	90.4	Very high	84.8	Confident	65 Å²	65	77.4 Å²	77.4	39%	0.394	37%	0.371	S	S	.	.	H	α-helix	trans	-64.1	-45.6	-179.8	172.5	0	0	0	0	111.6	T238 K239 H244 L245 I246	T238-V242 VanDerWaalsContact O-CG2 3.31Å; T238-V242 WeakPolarHBondContact O-CG2 3.38Å; T238-V242 PolarHBondContact O-N 3.44Å; K239-V242 PolarHBondContact O-N 3.24Å; V242-H244 VanDerWaalsContact C-N 3.32Å; V242-H244 PolarHBondContact O-N 3.43Å; V242-L245 WeakPolarHBondContact O-CB 3.33Å; V242-L245 PolarHBondContact O-N 2.94Å; V242-I246 HydrophobicContact CG1-CD1 3.95Å; V242-I246 WeakPolarHBondContact O-CG1 3.42Å; V242-I246 PolarHBondContact O-N 2.96Å
243	N	88.2	Confident	86.3	Confident	86 Å²	86	75.6 Å²	75.6	46%	0.46	37%	0.369	S	S	.	.	H	α-helix	trans	-61	-42.2	177.7	-74.7	-12.6	0	0	0	111.8	K239 W240 I246 Y247	K239-N243 WeakPolarHBondContact O-CB 3.49Å; K239-N243 VanDerWaalsContact O-CG 3.23Å; K239-N243 PolarHBondContact O-N 2.84Å; K239-N243 PolarHBondContact O-ND2 2.83Å; W240-N243 PolarHBondContact O-N 3.45Å; N243-I246 PolarHBondContact O-N 3.46Å; N243-Y247 WeakPolarHBondContact O-CB 3.4Å; N243-Y247 PolarHBondContact O-N 2.9Å
244	H	87.8	Confident	87.8	Confident	45 Å²	45	75.2 Å²	75.2	21%	0.208	38%	0.376	C	S	.	.	H	α-helix	trans	-70.5	-34.4	177.6	-155.5	72.7	0	0	0	112	A218 W240 F241 V242 Y247 Q248	A218-H244 HydrophobicContact CB-CB 3.99Å; W240-H244 WeakPolarHBondContact O-CB 3.37Å; W240-H244 PolarHBondContact O-N 3.25Å; F241-H244 PolarHBondContact O-N 2.94Å; V242-H244 VanDerWaalsContact C-N 3.32Å; V242-H244 PolarHBondContact O-N 3.43Å; H244-Y247 WeakPolarHBondContact O-CB 3.44Å; H244-Y247 PolarHBondContact O-N 3.23Å; H244-Q248 PolarHBondContact NE2-NE2 3.11Å; H244-Q248 VanDerWaalsContact O-CG 3.32Å; H244-Q248 WeakPolarHBondContact O-CG 3.28Å; H244-Q248 PolarHBondContact O-N 2.89Å
245	L	93.1	Very high	89.2	Confident	55 Å²	55	69.7 Å²	69.7	29%	0.288	35%	0.351	S	S	.	.	H	α-helix	trans	-60.9	-48.5	173.5	179.7	63.3	0	0	0	111	I211 C215 F241 V242 Y247 Q248 I249	I211-L245 HydrophobicContact CG2-CD1 3.46Å; I211-L245 VanDerWaalsContact CG2-CD1 3.46Å; C215-L245 WeakPolarHBondContact SG-CA 3.36Å; F241-L245 HydrophobicContact CE1-CD2 4.28Å; F241-L245 VanDerWaalsContact O-CB 3.3Å; F241-L245 WeakPolarHBondContact O-CB 3.47Å; F241-L245 PolarHBondContact O-N 3.5Å; V242-L245 WeakPolarHBondContact O-CB 3.33Å; V242-L245 PolarHBondContact O-N 2.94Å; L245-Y247 VanDerWaalsContact C-N 3.3Å; L245-Y247 PolarHBondContact O-N 3.24Å; L245-Q248 PolarHBondContact O-N 2.99Å; L245-I249 HydrophobicContact CD1-CD1 4.05Å; L245-I249 HydrophobicContact CD1-CG1 4.34Å; L245-I249 HydrophobicContact CG-CD1 3.87Å; L245-I249 WeakPolarHBondContact O-CB 3.2Å; L245-I249 VanDerWaalsContact O-CG1 3.24Å; L245-I249 WeakPolarHBondContact O-CG1 3.4Å; L245-I249 PolarHBondContact O-N 3.48Å
246	I	93.5	Very high	90.4	Very high	107 Å²	107	66.3 Å²	66.3	55%	0.549	34%	0.337	S	S	.	.	H	α-helix	trans	-59	-43.9	175.6	-66.1	165.8	0	0	0	110.5	V242 N243 I249 G250	V242-I246 HydrophobicContact CG1-CD1 3.95Å; V242-I246 WeakPolarHBondContact O-CG1 3.42Å; V242-I246 PolarHBondContact O-N 2.96Å; N243-I246 PolarHBondContact O-N 3.46Å; I246-I249 PolarHBondContact O-N 3.22Å; I246-G250 PolarHBondContact O-N 3.33Å
247	Y	91.4	Very high	91.3	Very high	119 Å²	119	69.7 Å²	69.7	47%	0.467	36%	0.356	S	S	.	.	H	α-helix	trans	-60.8	-45.6	176.8	176.7	-102.9	0	0	0	112.5	N243 H244 L245 G250 I251	N243-Y247 WeakPolarHBondContact O-CB 3.4Å; N243-Y247 PolarHBondContact O-N 2.9Å; H244-Y247 WeakPolarHBondContact O-CB 3.44Å; H244-Y247 PolarHBondContact O-N 3.23Å; L245-Y247 VanDerWaalsContact C-N 3.3Å; L245-Y247 PolarHBondContact O-N 3.24Å; Y247-G250 PolarHBondContact O-N 2.89Å; Y247-I251 HydrophobicContact CD1-CD1 3.89Å; Y247-I251 HydrophobicContact CE1-CD1 3.35Å; Y247-I251 HydrophobicContact CE1-CG1 4.4Å; Y247-I251 HydrophobicContact CE2-CD1 4.37Å; Y247-I251 PolarHBondContact O-N 3.41Å
248	Q	91.7	Very high	92.2	Very high	12 Å²	12	68.8 Å²	68.8	6%	0.056	36%	0.363	C	S	.	.	H	α-helix	trans	-63.9	-46.9	176.5	-68.4	-57.6	-34.7	0	0	111.1	I211 K214 H244 L245 G250 I251 Y252	I211-Q248 HydrophobicContact CG1-CB 4.35Å; I211-Q248 HydrophobicContact CG2-CB 4.15Å; K214-Q248 HydrophobicContact CB-CG 4.3Å; H244-Q248 PolarHBondContact NE2-NE2 3.11Å; H244-Q248 VanDerWaalsContact O-CG 3.32Å; H244-Q248 WeakPolarHBondContact O-CG 3.28Å; H244-Q248 PolarHBondContact O-N 2.89Å; L245-Q248 PolarHBondContact O-N 2.99Å; Q248-G250 VanDerWaalsContact C-N 3.26Å; Q248-G250 PolarHBondContact O-N 3.48Å; Q248-I251 WeakPolarHBondContact O-CB 3.36Å; Q248-I251 PolarHBondContact O-N 3.34Å; Q248-I251 VanDerWaalsContact O-N 3.08Å; Q248-Y252 VanDerWaalsContact O-CD2 3.26Å; Q248-Y252 WeakPolarHBondContact O-CD2 3.32Å; Q248-Y252 PolarHBondContact O-N 2.6Å
249	I	94.4	Very high	92.7	Very high	74 Å²	74	65.5 Å²	65.5	38%	0.379	34%	0.343	S	S	.	.	H	α-helix	trans	-56.6	-43.4	175.4	-67.2	168.2	0	0	0	110.1	L245 I246 I251 Y252 L253	L245-I249 HydrophobicContact CD1-CD1 4.05Å; L245-I249 HydrophobicContact CD1-CG1 4.34Å; L245-I249 HydrophobicContact CG-CD1 3.87Å; L245-I249 WeakPolarHBondContact O-CB 3.2Å; L245-I249 VanDerWaalsContact O-CG1 3.24Å; L245-I249 WeakPolarHBondContact O-CG1 3.4Å; L245-I249 PolarHBondContact O-N 3.48Å; I246-I249 PolarHBondContact O-N 3.22Å; I249-I251 VanDerWaalsContact C-N 3.34Å; I249-I251 PolarHBondContact O-N 3.24Å; I249-Y252 PolarHBondContact O-N 3.13Å; I249-L253 HydrophobicContact CG2-CD1 3.75Å; I249-L253 HydrophobicContact CG2-CG 4.16Å; I249-L253 WeakPolarHBondContact O-CB 3.32Å; I249-L253 WeakPolarHBondContact O-CG 3.45Å; I249-L253 PolarHBondContact O-N 3.45Å
250	G	94.9	Very high	93.2	Very high	38 Å²	38	62.9 Å²	62.9	39%	0.392	33%	0.332	S	S	.	.	H	α-helix	trans	-56.9	-43.7	175.2	0	0	0	0	0	113	I246 Y247 Q248 L253 S254	I246-G250 PolarHBondContact O-N 3.33Å; Y247-G250 PolarHBondContact O-N 2.89Å; Q248-G250 VanDerWaalsContact C-N 3.26Å; Q248-G250 PolarHBondContact O-N 3.48Å; G250-L253 PolarHBondContact O-N 3.42Å; G250-S254 WeakPolarHBondContact O-CB 3.32Å; G250-S254 PolarHBondContact O-N 3.49Å
251	I	92.9	Very high	93.8	Very high	26 Å²	26	59.2 Å²	59.2	13%	0.133	33%	0.329	C	S	.	.	H	α-helix	trans	-62.2	-47.4	174.7	-67	163.2	0	0	0	111	K183 I186 Y247 Q248 I249 L253 S254 I255	K183-I251 HydrophobicContact CG-CG2 4.44Å; I186-I251 HydrophobicContact CD1-CG2 4.2Å; Y247-I251 HydrophobicContact CD1-CD1 3.89Å; Y247-I251 HydrophobicContact CE1-CD1 3.35Å; Y247-I251 HydrophobicContact CE1-CG1 4.4Å; Y247-I251 HydrophobicContact CE2-CD1 4.37Å; Y247-I251 PolarHBondContact O-N 3.41Å; Q248-I251 WeakPolarHBondContact O-CB 3.36Å; Q248-I251 PolarHBondContact O-N 3.34Å; Q248-I251 VanDerWaalsContact O-N 3.08Å; I249-I251 VanDerWaalsContact C-N 3.34Å; I249-I251 PolarHBondContact O-N 3.24Å; I251-L253 PolarHBondContact O-N 2.97Å; I251-S254 PolarHBondContact O-N 3.24Å; I251-S254 PolarHBondContact O-OG 2.93Å; I251-I255 PolarHBondContact O-N 3.28Å
252	Y	95.6	Very high	94.1	Very high	18 Å²	18	63.3 Å²	63.3	7%	0.071	35%	0.347	C	S	.	.	H	α-helix	trans	-61.7	-46.1	179.7	-85.8	-105.9	0	0	0	111.5	F185 I186 C207 H210 I211 Q248 I249 S254 I255 I256	F185-Y252 WeakPolarHBondContact CZ-OH 3.22Å; I186-Y252 HydrophobicContact CD1-CD1 4.32Å; I186-Y252 HydrophobicContact CD1-CD2 3.77Å; I186-Y252 HydrophobicContact CD1-CE1 4.04Å; I186-Y252 HydrophobicContact CD1-CE2 3.48Å; I186-Y252 VanDerWaalsContact CD1-CE2 3.48Å; I186-Y252 HydrophobicContact CD1-CG 4.22Å; I186-Y252 HydrophobicContact CG1-CD1 4.28Å; I186-Y252 HydrophobicContact CG1-CE1 3.77Å; I186-Y252 HydrophobicContact CG1-CE2 4.09Å; I186-Y252 HydrophobicContact CG2-CD1 3.83Å; I186-Y252 HydrophobicContact CG2-CE1 4.06Å; I186-Y252 HydrophobicContact CG2-CG 4.3Å; C207-Y252 HydrophobicContact CB-CE1 3.74Å; H210-Y252 AromaticContact ND1-CE2 3.9Å; H210-Y252 AromaticContact ND1-CZ 3.84Å; H210-Y252 PolarHBondContact ND1-OH 3.48Å; I211-Y252 HydrophobicContact CD1-CD1 4.41Å; I211-Y252 HydrophobicContact CD1-CD2 3.99Å; I211-Y252 HydrophobicContact CD1-CE1 4.21Å; I211-Y252 HydrophobicContact CD1-CE2 3.75Å; I211-Y252 HydrophobicContact CD1-CG 4.29Å; I211-Y252 HydrophobicContact CG1-CD2 4.15Å; I211-Y252 HydrophobicContact CG1-CE2 3.52Å; Q248-Y252 VanDerWaalsContact O-CD2 3.26Å; Q248-Y252 WeakPolarHBondContact O-CD2 3.32Å; Q248-Y252 PolarHBondContact O-N 2.6Å; I249-Y252 PolarHBondContact O-N 3.13Å; Y252-S254 VanDerWaalsContact C-N 3.31Å; Y252-S254 PolarHBondContact O-N 3.39Å; Y252-I255 PolarHBondContact O-N 2.99Å; Y252-I255 VanDerWaalsContact O-N 3.12Å; Y252-I256 HydrophobicContact CD1-CD1 4.43Å; Y252-I256 WeakPolarHBondContact O-CB 3.25Å; Y252-I256 VanDerWaalsContact O-CG1 3.26Å; Y252-I256 WeakPolarHBondContact O-CG1 3.22Å; Y252-I256 PolarHBondContact O-N 2.86Å
253	L	96.6	Very high	94.4	Very high	88 Å²	88	60.2 Å²	60.2	46%	0.461	33%	0.328	S	S	.	.	H	α-helix	trans	-63	-37	177.3	-71.1	176.1	0	0	0	112.1	I249 G250 I251 I255 I256 V257	I249-L253 HydrophobicContact CG2-CD1 3.75Å; I249-L253 HydrophobicContact CG2-CG 4.16Å; I249-L253 WeakPolarHBondContact O-CB 3.32Å; I249-L253 WeakPolarHBondContact O-CG 3.45Å; I249-L253 PolarHBondContact O-N 3.45Å; G250-L253 PolarHBondContact O-N 3.42Å; I251-L253 PolarHBondContact O-N 2.97Å; L253-I255 PolarHBondContact O-N 2.86Å; L253-I255 VanDerWaalsContact O-N 3.09Å; L253-I256 PolarHBondContact O-N 2.8Å; L253-V257 HydrophobicContact CD2-CG2 4.41Å; L253-V257 WeakPolarHBondContact O-CB 3.41Å; L253-V257 WeakPolarHBondContact O-CG2 3.25Å; L253-V257 PolarHBondContact O-N 2.87Å
254	S	95.7	Very high	94.7	Very high	76 Å²	76	57.1 Å²	57.1	53%	0.531	31%	0.313	S	S	.	.	H	α-helix	trans	-62	-17.6	176.7	77.1	0	0	0	0	113.9	G250 I251 Y252 P258	G250-S254 WeakPolarHBondContact O-CB 3.32Å; G250-S254 PolarHBondContact O-N 3.49Å; I251-S254 PolarHBondContact O-N 3.24Å; I251-S254 PolarHBondContact O-OG 2.93Å; Y252-S254 VanDerWaalsContact C-N 3.31Å; Y252-S254 PolarHBondContact O-N 3.39Å; S254-P258 VanDerWaalsContact O-CD 3.28Å; S254-P258 WeakPolarHBondContact O-CD 3.16Å; S254-P258 VanDerWaalsContact O-CG 3.31Å; S254-P258 WeakPolarHBondContact O-CG 3.35Å
255	I	96.4	Very high	95.1	Very high	24 Å²	24	58.7 Å²	58.7	12%	0.123	33%	0.326	C	S	.	.	H	α-helix	trans	-104.5	-45.9	176.8	-61.2	170.2	0	0	0	110.7	K183 I186 F187 I251 Y252 L253 V257 P258 C259	K183-I255 HydrophobicContact CB-CD1 4.09Å; K183-I255 HydrophobicContact CG-CD1 4.45Å; I186-I255 HydrophobicContact CB-CD1 3.95Å; I186-I255 HydrophobicContact CD1-CD1 4.48Å; I186-I255 HydrophobicContact CG2-CB 4.17Å; I186-I255 HydrophobicContact CG2-CD1 3.82Å; I186-I255 HydrophobicContact CG2-CG2 4.16Å; F187-I255 HydrophobicContact CB-CG2 4.06Å; F187-I255 HydrophobicContact CD2-CG2 4.25Å; I251-I255 PolarHBondContact O-N 3.28Å; Y252-I255 PolarHBondContact O-N 2.99Å; Y252-I255 VanDerWaalsContact O-N 3.12Å; L253-I255 PolarHBondContact O-N 2.86Å; L253-I255 VanDerWaalsContact O-N 3.09Å; I255-V257 PolarHBondContact O-N 3.39Å; I255-P258 WeakPolarHBondContact O-CD 3.49Å; I255-C259 WeakPolarHBondContact O-CB 3.22Å; I255-C259 PolarHBondContact O-N 3.06Å; I255-C259 PolarHBondContact O-SG 2.94Å
256	I	96.7	Very high	95.2	Very high	63 Å²	63	57.2 Å²	57.2	32%	0.323	32%	0.318	S	S	.	.	H	α-helix	trans	-59.8	-48.8	-178.7	-69.1	165.8	0	0	0	110.6	V190 Y252 L253 C259 F260	V190-I256 HydrophobicContact CG2-CB 4.49Å; V190-I256 HydrophobicContact CG2-CG1 3.56Å; Y252-I256 HydrophobicContact CD1-CD1 4.43Å; Y252-I256 WeakPolarHBondContact O-CB 3.25Å; Y252-I256 VanDerWaalsContact O-CG1 3.26Å; Y252-I256 WeakPolarHBondContact O-CG1 3.22Å; Y252-I256 PolarHBondContact O-N 2.86Å; L253-I256 PolarHBondContact O-N 2.8Å; I256-C259 PolarHBondContact O-N 2.81Å; I256-F260 VanDerWaalsContact O-CB 3.23Å; I256-F260 WeakPolarHBondContact O-CB 3.43Å; I256-F260 PolarHBondContact O-N 3.29Å
257	V	96.9	Very high	95.2	Very high	87 Å²	87	52.1 Å²	52.1	53%	0.527	29%	0.292	S	S	.	.	H	α-helix	trans	-63.7	-50.6	-173.2	173.3	0	0	0	0	111.7	L253 I255 C259 F260 A261	L253-V257 HydrophobicContact CD2-CG2 4.41Å; L253-V257 WeakPolarHBondContact O-CB 3.41Å; L253-V257 WeakPolarHBondContact O-CG2 3.25Å; L253-V257 PolarHBondContact O-N 2.87Å; I255-V257 PolarHBondContact O-N 3.39Å; V257-C259 PolarHBondContact O-N 3.22Å; V257-F260 PolarHBondContact O-N 3.24Å; V257-A261 VanDerWaalsContact O-CB 3.31Å; V257-A261 WeakPolarHBondContact O-CB 3.14Å; V257-A261 PolarHBondContact O-N 3.38Å
258	P	97.4	Very high	95.4	Very high	77 Å²	77	51 Å²	51	50%	0.5	29%	0.287	S	S	.	.	H	α-helix	trans	-63	-41.1	177.3	-25.9	37.1	0	0	0	113.7	S254 I255 A261 F262	S254-P258 VanDerWaalsContact O-CD 3.28Å; S254-P258 WeakPolarHBondContact O-CD 3.16Å; S254-P258 VanDerWaalsContact O-CG 3.31Å; S254-P258 WeakPolarHBondContact O-CG 3.35Å; I255-P258 WeakPolarHBondContact O-CD 3.49Å; P258-A261 PolarHBondContact O-N 2.96Å; P258-F262 WeakPolarHBondContact O-CB 3.5Å; P258-F262 PolarHBondContact O-N 3.02Å
259	C	96.7	Very high	95.5	Very high	18 Å²	18	58.5 Å²	58.5	12%	0.122	32%	0.315	C	S	.	.	H	α-helix	trans	-64.8	-40.9	178.4	-70.8	0	0	0	0	112	V190 L194 I255 I256 V257 F262 S263	V190-C259 HydrophobicContact CG1-CB 3.54Å; L194-C259 HydrophobicContact CD1-CB 3.85Å; L194-C259 WeakPolarHBondContact CD1-O 3.4Å; I255-C259 WeakPolarHBondContact O-CB 3.22Å; I255-C259 PolarHBondContact O-N 3.06Å; I255-C259 PolarHBondContact O-SG 2.94Å; I256-C259 PolarHBondContact O-N 2.81Å; V257-C259 PolarHBondContact O-N 3.22Å; C259-F262 PolarHBondContact O-N 3.39Å; C259-S263 PolarHBondContact O-N 3.05Å
260	F	95.3	Very high	95.5	Very high	71 Å²	71	56.5 Å²	56.5	31%	0.311	31%	0.306	S	S	.	.	H	α-helix	trans	-70.1	-40.1	177.8	-161	-92.9	0	0	0	111.9	L194 I256 V257 F262 S263 C264 I276	L194-F260 HydrophobicContact CD2-CD2 3.78Å; L194-F260 HydrophobicContact CD2-CE2 4.38Å; I256-F260 VanDerWaalsContact O-CB 3.23Å; I256-F260 WeakPolarHBondContact O-CB 3.43Å; I256-F260 PolarHBondContact O-N 3.29Å; V257-F260 PolarHBondContact O-N 3.24Å; F260-F262 VanDerWaalsContact C-N 3.32Å; F260-F262 PolarHBondContact O-N 3.03Å; F260-S263 WeakPolarHBondContact O-CB 3.27Å; F260-S263 PolarHBondContact O-N 3.23Å; F260-C264 PolarHBondContact O-N 3.12Å; F260-C264 PolarHBondContact O-SG 3.47Å; F260-I276 HydrophobicContact CE1-CD1 3.97Å; F260-I276 HydrophobicContact CE1-CG1 4.16Å; F260-I276 HydrophobicContact CE1-CG2 4.16Å; F260-I276 HydrophobicContact CE2-CG2 4.24Å; F260-I276 HydrophobicContact CZ-CB 4.47Å; F260-I276 HydrophobicContact CZ-CD1 4.17Å; F260-I276 HydrophobicContact CZ-CG1 4.27Å; F260-I276 HydrophobicContact CZ-CG2 3.42Å; F260-I276 VanDerWaalsContact CZ-CG2 3.42Å
261	A	95.9	Very high	95.4	Very high	51 Å²	51	55 Å²	55	42%	0.421	29%	0.289	S	S	.	.	H	α-helix	trans	-59.5	-44.1	172.7	0	0	0	0	0	111.3	V257 P258 S263 C264 V265	V257-A261 VanDerWaalsContact O-CB 3.31Å; V257-A261 WeakPolarHBondContact O-CB 3.14Å; V257-A261 PolarHBondContact O-N 3.38Å; P258-A261 PolarHBondContact O-N 2.96Å; A261-S263 PolarHBondContact O-N 2.74Å; A261-C264 PolarHBondContact O-N 3.24Å; A261-V265 WeakPolarHBondContact O-CG2 3.3Å; A261-V265 PolarHBondContact O-N 3.5Å
262	F	95.3	Very high	95.4	Very high	129 Å²	129	59.3 Å²	59.3	57%	0.566	31%	0.312	S	S	*	.	H	α-helix	trans	-60.1	-43.6	173.6	179.8	-106.4	0	0	0	112.1	P258 C259 F260 C264 V265 L266	P258-F262 WeakPolarHBondContact O-CB 3.5Å; P258-F262 PolarHBondContact O-N 3.02Å; C259-F262 PolarHBondContact O-N 3.39Å; F260-F262 VanDerWaalsContact C-N 3.32Å; F260-F262 PolarHBondContact O-N 3.03Å; F262-C264 VanDerWaalsContact C-N 3.32Å; F262-C264 PolarHBondContact O-N 2.93Å; F262-V265 PolarHBondContact O-N 3.21Å; F262-L266 HydrophobicContact CD1-CD1 4.03Å; F262-L266 HydrophobicContact CD1-CG 4.43Å; F262-L266 HydrophobicContact CE1-CD1 3.47Å; F262-L266 VanDerWaalsContact CE1-CD1 3.47Å; F262-L266 HydrophobicContact CE1-CG 4.05Å; F262-L266 HydrophobicContact CE2-CD2 4.45Å; F262-L266 HydrophobicContact CE2-CG 4.44Å; F262-L266 HydrophobicContact CZ-CD1 3.84Å; F262-L266 HydrophobicContact CZ-CD2 4.1Å; F262-L266 HydrophobicContact CZ-CG 4.04Å; F262-L266 WeakPolarHBondContact O-CG 3.34Å; F262-L266 PolarHBondContact O-N 3.46Å
263	S	95.2	Very high	95.2	Very high	0 Å²	0	63 Å²	63	0%	0	33%	0.33	C	S	.	.	H	α-helix	trans	-58.7	-42.4	173.8	-170.7	0	0	0	0	112.1	C259 F260 A261 V265 L266 D267 Q278	C259-S263 PolarHBondContact O-N 3.05Å; F260-S263 WeakPolarHBondContact O-CB 3.27Å; F260-S263 PolarHBondContact O-N 3.23Å; A261-S263 PolarHBondContact O-N 2.74Å; S263-V265 VanDerWaalsContact C-N 3.33Å; S263-V265 PolarHBondContact O-N 3.13Å; S263-L266 PolarHBondContact O-N 3.45Å; S263-D267 PolarHBondContact O-N 2.87Å; S263-Q278 PolarHBondContact OG-NE2 3.38Å
264	C	95.3	Very high	95.1	Very high	21 Å²	21	67.2 Å²	67.2	14%	0.142	34%	0.34	C	S	.	.	H	α-helix	trans	-66	-35.9	178.2	-64.4	0	0	0	0	112.2	F260 A261 F262 D267 R268 W274	F260-C264 PolarHBondContact O-N 3.12Å; F260-C264 PolarHBondContact O-SG 3.47Å; A261-C264 PolarHBondContact O-N 3.24Å; F262-C264 VanDerWaalsContact C-N 3.32Å; F262-C264 PolarHBondContact O-N 2.93Å; C264-D267 PolarHBondContact O-N 3.45Å; C264-R268 WeakPolarHBondContact O-CB 3.46Å; C264-R268 PolarHBondContact O-N 3.26Å; C264-W274 HydrophobicContact CB-CE3 4.34Å; C264-W274 HydrophobicContact CB-CZ3 4.25Å
265	V	96.2	Very high	94.9	Very high	79 Å²	79	64.5 Å²	64.5	48%	0.479	32%	0.319	S	S	.	.	H	α-helix	trans	-65.6	-41.9	174	170.9	0	0	0	0	110.8	A261 F262 S263 R268 W269 W274	A261-V265 WeakPolarHBondContact O-CG2 3.3Å; A261-V265 PolarHBondContact O-N 3.5Å; F262-V265 PolarHBondContact O-N 3.21Å; S263-V265 VanDerWaalsContact C-N 3.33Å; S263-V265 PolarHBondContact O-N 3.13Å; V265-R268 PolarHBondContact O-N 3.47Å; V265-W269 PolarHBondContact O-N 3.01Å; V265-W274 HydrophobicContact CG2-CH2 4.33Å; V265-W274 HydrophobicContact CG2-CZ3 4.34Å
266	L	95	Very high	94.7	Very high	24 Å²	24	66.7 Å²	66.7	13%	0.126	33%	0.33	C	S	.	.	H	α-helix	trans	-63.2	-43.4	173.7	-68.8	-178.5	0	0	0	111.6	P65 V66 L69 F262 S263 R268 W269 T270	P65-L266 HydrophobicContact CG-CB 3.99Å; V66-L266 HydrophobicContact CG2-CD1 3.85Å; L69-L266 HydrophobicContact CD1-CD1 4.11Å; L69-L266 HydrophobicContact CD1-CD2 3.9Å; F262-L266 HydrophobicContact CD1-CD1 4.03Å; F262-L266 HydrophobicContact CD1-CG 4.43Å; F262-L266 HydrophobicContact CE1-CD1 3.47Å; F262-L266 VanDerWaalsContact CE1-CD1 3.47Å; F262-L266 HydrophobicContact CE1-CG 4.05Å; F262-L266 HydrophobicContact CE2-CD2 4.45Å; F262-L266 HydrophobicContact CE2-CG 4.44Å; F262-L266 HydrophobicContact CZ-CD1 3.84Å; F262-L266 HydrophobicContact CZ-CD2 4.1Å; F262-L266 HydrophobicContact CZ-CG 4.04Å; F262-L266 WeakPolarHBondContact O-CG 3.34Å; F262-L266 PolarHBondContact O-N 3.46Å; S263-L266 PolarHBondContact O-N 3.45Å; L266-R268 VanDerWaalsContact C-N 3.31Å; L266-R268 PolarHBondContact O-N 3.47Å; L266-W269 PolarHBondContact O-N 3.35Å; L266-W269 VanDerWaalsContact O-N 3.13Å; L266-T270 WeakPolarHBondContact O-CB 3.43Å; L266-T270 PolarHBondContact O-N 3.04Å; L266-T270 PolarHBondContact O-OG1 3.46Å
267	D	94.3	Very high	94.5	Very high	0 Å²	0	63.8 Å²	63.8	0%	0	32%	0.316	C	S	.	.	H	α-helix	trans	-60.8	-41.8	175.9	-73.1	-13.2	0	0	0	111	P65 S263 C264 W269 T270 F271 I275 N277	P65-D267 WeakPolarHBondContact CD-OD1 3.13Å; S263-D267 PolarHBondContact O-N 2.87Å; C264-D267 PolarHBondContact O-N 3.45Å; D267-W269 VanDerWaalsContact C-N 3.32Å; D267-W269 PolarHBondContact O-N 2.86Å; D267-T270 PolarHBondContact O-N 3.48Å; D267-F271 HydrophobicContact CB-CD2 4.25Å; D267-F271 WeakPolarHBondContact O-CB 3.49Å; D267-F271 WeakPolarHBondContact O-CD2 3.32Å; D267-F271 PolarHBondContact O-N 3.35Å; D267-I275 VanDerWaalsContact OD2-O 3.12Å; D267-N277 VanDerWaalsContact CG-ND2 3.33Å; D267-N277 PolarHBondContact OD1-ND2 3.28Å; D267-N277 PolarHBondContact OD2-N 2.89Å; D267-N277 PolarHBondContact OD2-ND2 3.27Å
268	R	95.4	Very high	94.4	Very high	95 Å²	95	60.2 Å²	60.2	36%	0.358	29%	0.293	S	S	.	.	H	α-helix	trans	-60.4	-41.1	173.7	174.3	60.6	-175	166.9	8.2	112.3	C264 V265 L266 N272 Q273 W274	C264-R268 WeakPolarHBondContact O-CB 3.46Å; C264-R268 PolarHBondContact O-N 3.26Å; V265-R268 PolarHBondContact O-N 3.47Å; L266-R268 VanDerWaalsContact C-N 3.31Å; L266-R268 PolarHBondContact O-N 3.47Å; R268-N272 PolarHBondContact NH1-O 3.33Å; R268-N272 PolarHBondContact NH2-OD1 3.17Å; R268-N272 WeakPolarHBondContact O-CA 3.41Å; R268-N272 PolarHBondContact O-N 3.02Å; R268-N272 VanDerWaalsContact O-N 3.09Å; R268-Q273 WeakPolarHBondContact CA-O 3.4Å; R268-W274 HydrophobicContact CB-CD2 4.02Å; R268-W274 HydrophobicContact CB-CE3 3.79Å; R268-W274 HydrophobicContact CB-CH2 4.1Å; R268-W274 HydrophobicContact CB-CZ2 4.3Å; R268-W274 HydrophobicContact CB-CZ3 3.83Å; R268-W274 HydrophobicContact CG-CD2 4.15Å; R268-W274 HydrophobicContact CG-CE3 4.35Å; R268-W274 HydrophobicContact CG-CH2 4.13Å; R268-W274 HydrophobicContact CG-CZ2 3.9Å; R268-W274 HydrophobicContact CG-CZ3 4.34Å
269	W	93.7	Very high	94.1	Very high	169 Å²	169	63.6 Å²	63.6	64%	0.64	30%	0.296	S	S	*	.	H	α-helix	trans	-69.6	-43.4	178.4	177.1	79	0	0	0	112	L69 V265 L266 D267	L69-W269 HydrophobicContact CD1-CZ3 4.48Å; L69-W269 HydrophobicContact CD2-CH2 4.07Å; L69-W269 HydrophobicContact CD2-CZ3 3.72Å; V265-W269 PolarHBondContact O-N 3.01Å; L266-W269 PolarHBondContact O-N 3.35Å; L266-W269 VanDerWaalsContact O-N 3.13Å; D267-W269 VanDerWaalsContact C-N 3.32Å; D267-W269 PolarHBondContact O-N 2.86Å
270	T	93.2	Very high	93.9	Very high	32 Å²	32	64.6 Å²	64.6	20%	0.196	30%	0.3	C	S	.	.	H	α-helix	trans	-75.1	-46.1	-177	-60.3	0	0	0	0	112.9	W45 P65 L266 D267	W45-T270 HydrophobicContact CH2-CG2 4.05Å; W45-T270 HydrophobicContact CZ2-CG2 3.46Å; W45-T270 VanDerWaalsContact CZ2-CG2 3.46Å; P65-T270 HydrophobicContact CB-CG2 4.2Å; P65-T270 WeakPolarHBondContact CB-OG1 3.25Å; L266-T270 WeakPolarHBondContact O-CB 3.43Å; L266-T270 PolarHBondContact O-N 3.04Å; L266-T270 PolarHBondContact O-OG1 3.46Å; D267-T270 PolarHBondContact O-N 3.48Å
271	F	93.3	Very high	93.6	Very high	7 Å²	7	62.4 Å²	62.4	3%	0.031	29%	0.29	C	S	.	.	H	α-helix	trans	-102.1	-1.2	-171.9	-57.7	-69.2	0	0	0	113.6	W56 P58 A61 D267 Q273 I275	W56-F271 AromaticContact CE3-CE1 4Å; W56-F271 HydrophobicContact CE3-CE1 4Å; W56-F271 AromaticContact CE3-CZ 3.88Å; W56-F271 HydrophobicContact CE3-CZ 3.88Å; W56-F271 HydrophobicContact CZ3-CZ 4.08Å; W56-F271 WeakPolarHBondContact O-CE1 3.43Å; P58-F271 HydrophobicContact CB-CB 4.41Å; A61-F271 HydrophobicContact CB-CD1 3.84Å; A61-F271 HydrophobicContact CB-CD2 3.87Å; A61-F271 HydrophobicContact CB-CE1 3.83Å; A61-F271 HydrophobicContact CB-CE2 3.87Å; A61-F271 HydrophobicContact CB-CG 3.86Å; A61-F271 HydrophobicContact CB-CZ 3.84Å; D267-F271 HydrophobicContact CB-CD2 4.25Å; D267-F271 WeakPolarHBondContact O-CB 3.49Å; D267-F271 WeakPolarHBondContact O-CD2 3.32Å; D267-F271 PolarHBondContact O-N 3.35Å; F271-Q273 PolarHBondContact O-N 2.88Å; F271-Q273 VanDerWaalsContact O-N 3.13Å; F271-I275 HydrophobicContact CB-CD1 3.85Å; F271-I275 HydrophobicContact CD2-CD1 4.49Å; F271-I275 HydrophobicContact CG-CD1 4.27Å
272	N	92.6	Very high	93.3	Very high	116 Å²	116	62.7 Å²	62.7	62%	0.62	28%	0.284	S	S	*	.	S	Bend	trans	53.7	28.8	-174.8	-163.7	24.6	0	0	0	113.5	R268	R268-N272 PolarHBondContact NH1-O 3.33Å; R268-N272 PolarHBondContact NH2-OD1 3.17Å; R268-N272 WeakPolarHBondContact O-CA 3.41Å; R268-N272 PolarHBondContact O-N 3.02Å; R268-N272 VanDerWaalsContact O-N 3.09Å
273	Q	92.5	Very high	92.9	Very high	95 Å²	95	62 Å²	62	44%	0.444	28%	0.281	S	S	.	.	S	Bend	trans	-150.1	146.3	-179	-67	-172.8	-5.4	0	0	109.3	R268 F271 I275	R268-Q273 WeakPolarHBondContact CA-O 3.4Å; F271-Q273 PolarHBondContact O-N 2.88Å; F271-Q273 VanDerWaalsContact O-N 3.13Å; Q273-I275 HydrophobicContact CB-CD1 3.86Å; Q273-I275 HydrophobicContact CB-CG1 3.85Å; Q273-I275 PolarHBondContact O-N 3.47Å
274	W	93.9	Very high	92.5	Very high	177 Å²	177	64.5 Å²	64.5	67%	0.67	29%	0.292	S	S	*	.			trans	-75.5	106.3	172.3	-68.9	106.9	0	0	0	108.8	C264 V265 R268	C264-W274 HydrophobicContact CB-CE3 4.34Å; C264-W274 HydrophobicContact CB-CZ3 4.25Å; V265-W274 HydrophobicContact CG2-CH2 4.33Å; V265-W274 HydrophobicContact CG2-CZ3 4.34Å; R268-W274 HydrophobicContact CB-CD2 4.02Å; R268-W274 HydrophobicContact CB-CE3 3.79Å; R268-W274 HydrophobicContact CB-CH2 4.1Å; R268-W274 HydrophobicContact CB-CZ2 4.3Å; R268-W274 HydrophobicContact CB-CZ3 3.83Å; R268-W274 HydrophobicContact CG-CD2 4.15Å; R268-W274 HydrophobicContact CG-CE3 4.35Å; R268-W274 HydrophobicContact CG-CH2 4.13Å; R268-W274 HydrophobicContact CG-CZ2 3.9Å; R268-W274 HydrophobicContact CG-CZ3 4.34Å
275	I	90.8	Very high	91.8	Very high	19 Å²	19	65.7 Å²	65.7	10%	0.097	30%	0.297	C	S	.	.			trans	-128.8	152.1	-176.4	-58.5	176.1	0	0	0	108.1	P58 A61 D267 F271 Q273 N280	P58-I275 WeakPolarHBondContact O-CD1 3.29Å; A61-I275 HydrophobicContact CB-CD1 3.57Å; A61-I275 HydrophobicContact CB-CG2 3.95Å; D267-I275 VanDerWaalsContact OD2-O 3.12Å; F271-I275 HydrophobicContact CB-CD1 3.85Å; F271-I275 HydrophobicContact CD2-CD1 4.49Å; F271-I275 HydrophobicContact CG-CD1 4.27Å; Q273-I275 HydrophobicContact CB-CD1 3.86Å; Q273-I275 HydrophobicContact CB-CG1 3.85Å; Q273-I275 PolarHBondContact O-N 3.47Å; I275-N280 WeakPolarHBondContact CG2-ND2 3.22Å
276	I	94	Very high	90.9	Very high	71 Å²	71	67.5 Å²	67.5	36%	0.364	30%	0.303	S	S	.	.			trans	-113.2	95	167	-61.6	173.9	0	0	0	106.7	F260 Q278 W279 N280	F260-I276 HydrophobicContact CE1-CD1 3.97Å; F260-I276 HydrophobicContact CE1-CG1 4.16Å; F260-I276 HydrophobicContact CE1-CG2 4.16Å; F260-I276 HydrophobicContact CE2-CG2 4.24Å; F260-I276 HydrophobicContact CZ-CB 4.47Å; F260-I276 HydrophobicContact CZ-CD1 4.17Å; F260-I276 HydrophobicContact CZ-CG1 4.27Å; F260-I276 HydrophobicContact CZ-CG2 3.42Å; F260-I276 VanDerWaalsContact CZ-CG2 3.42Å; I276-Q278 PolarHBondContact O-N 3.5Å; I276-W279 HydrophobicContact CB-CB 4.07Å; I276-W279 HydrophobicContact CG2-CB 3.77Å; I276-W279 WeakPolarHBondContact O-CB 3.46Å; I276-W279 PolarHBondContact O-N 3.41Å; I276-W279 VanDerWaalsContact O-N 3.09Å; I276-N280 PolarHBondContact O-N 3.21Å
277	N	92.5	Very high	90	Very high	2 Å²	2	73.6 Å²	73.6	1%	0.011	33%	0.329	C	S	.	.	H	α-helix	trans	-59.8	-31	-175.3	69.5	54.6	0	0	0	112.4	S64 D267 W279 N280 F281	S64-N277 WeakPolarHBondContact CA-ND2 3.46Å; D267-N277 VanDerWaalsContact CG-ND2 3.33Å; D267-N277 PolarHBondContact OD1-ND2 3.28Å; D267-N277 PolarHBondContact OD2-N 2.89Å; D267-N277 PolarHBondContact OD2-ND2 3.27Å; N277-W279 VanDerWaalsContact C-N 3.33Å; N277-W279 PolarHBondContact O-N 2.83Å; N277-N280 PolarHBondContact O-N 3.31Å; N277-F281 WeakPolarHBondContact O-CB 3.47Å; N277-F281 PolarHBondContact O-N 3.4Å
278	Q	93	Very high	89.1	Confident	12 Å²	12	77.3 Å²	77.3	6%	0.056	36%	0.355	C	S	.	.	H	α-helix	trans	-68.9	-34.2	179.9	-60.1	83.6	6.3	0	0	111.6	L194 P197 S263 I276 I282	L194-Q278 PolarHBondContact O-NE2 2.92Å; L194-Q278 VanDerWaalsContact O-NE2 3.1Å; P197-Q278 HydrophobicContact CG-CB 3.82Å; P197-Q278 HydrophobicContact CG-CG 3.77Å; S263-Q278 PolarHBondContact OG-NE2 3.38Å; I276-Q278 PolarHBondContact O-N 3.5Å; Q278-I282 VanDerWaalsContact O-CG1 3.26Å; Q278-I282 WeakPolarHBondContact O-CG1 3.48Å; Q278-I282 PolarHBondContact O-N 2.84Å
279	W	91.8	Very high	87.8	Confident	148 Å²	148	73.8 Å²	73.8	56%	0.561	35%	0.348	S	S	*	.	H	α-helix	trans	-69.4	-43.3	173.5	176.1	-108.4	0	0	0	111.1	I276 N277 F281 I282 K283	I276-W279 HydrophobicContact CB-CB 4.07Å; I276-W279 HydrophobicContact CG2-CB 3.77Å; I276-W279 WeakPolarHBondContact O-CB 3.46Å; I276-W279 PolarHBondContact O-N 3.41Å; I276-W279 VanDerWaalsContact O-N 3.09Å; N277-W279 VanDerWaalsContact C-N 3.33Å; N277-W279 PolarHBondContact O-N 2.83Å; W279-F281 VanDerWaalsContact C-N 3.3Å; W279-F281 PolarHBondContact O-N 3.36Å; W279-I282 PolarHBondContact O-N 3.41Å; W279-K283 WeakPolarHBondContact O-CB 3.43Å; W279-K283 PolarHBondContact O-N 3.09Å
280	N	92.2	Very high	86.4	Confident	38 Å²	38	66 Å²	66	20%	0.203	32%	0.32	C	S	.	.	H	α-helix	trans	-61	-40.8	175.4	-70.2	-4.6	0	0	0	111.5	I60 I275 I276 N277 K283 F284	I60-N280 PolarHBondContact O-ND2 2.99Å; I275-N280 WeakPolarHBondContact CG2-ND2 3.22Å; I276-N280 PolarHBondContact O-N 3.21Å; N277-N280 PolarHBondContact O-N 3.31Å; N280-K283 PolarHBondContact O-N 3.17Å; N280-F284 VanDerWaalsContact O-CB 3.28Å; N280-F284 WeakPolarHBondContact O-CB 3.37Å; N280-F284 PolarHBondContact O-N 3.5Å
281	F	90.2	Very high	85	Confident	25 Å²	25	65.2 Å²	65.2	11%	0.11	32%	0.316	C	S	.	.	H	α-helix	trans	-59.6	-50	174.3	-179.2	-87.7	0	0	0	112.3	L62 P197 T198 N277 W279 K283 F284 N285	L62-F281 HydrophobicContact CD1-CB 4.37Å; P197-F281 HydrophobicContact CB-CD1 3.69Å; P197-F281 HydrophobicContact CB-CE1 4.13Å; P197-F281 HydrophobicContact CB-CG 4.4Å; P197-F281 HydrophobicContact CG-CB 4.05Å; P197-F281 HydrophobicContact CG-CD1 3.72Å; P197-F281 HydrophobicContact CG-CE1 4.42Å; P197-F281 HydrophobicContact CG-CG 3.92Å; T198-F281 HydrophobicContact CG2-CE1 3.9Å; T198-F281 HydrophobicContact CG2-CZ 3.84Å; N277-F281 WeakPolarHBondContact O-CB 3.47Å; N277-F281 PolarHBondContact O-N 3.4Å; W279-F281 VanDerWaalsContact C-N 3.3Å; W279-F281 PolarHBondContact O-N 3.36Å; F281-K283 VanDerWaalsContact C-N 3.32Å; F281-K283 PolarHBondContact O-N 3.44Å; F281-F284 PolarHBondContact O-N 3.5Å; F281-N285 WeakPolarHBondContact CD2-ND2 3.48Å; F281-N285 WeakPolarHBondContact CE2-ND2 3.49Å; F281-N285 VanDerWaalsContact CZ-ND2 3.33Å; F281-N285 WeakPolarHBondContact CZ-ND2 3.13Å; F281-N285 WeakPolarHBondContact O-CB 3.29Å; F281-N285 PolarHBondContact O-N 3.12Å; F281-N285 PolarHBondContact O-ND2 2.85Å
282	I	88	Confident	83.6	Confident	58 Å²	58	73 Å²	73	30%	0.297	35%	0.345	S	S	.	.	H	α-helix	trans	-61.1	-45.8	178.1	-70.3	168	0	0	0	109.7	Q278 W279 F284 N285 L286	Q278-I282 VanDerWaalsContact O-CG1 3.26Å; Q278-I282 WeakPolarHBondContact O-CG1 3.48Å; Q278-I282 PolarHBondContact O-N 2.84Å; W279-I282 PolarHBondContact O-N 3.41Å; I282-F284 PolarHBondContact O-N 2.93Å; I282-N285 PolarHBondContact O-N 3.28Å; I282-L286 HydrophobicContact CG2-CD1 3.72Å; I282-L286 HydrophobicContact CG2-CG 4.33Å; I282-L286 VanDerWaalsContact O-CB 3.31Å; I282-L286 WeakPolarHBondContact O-CB 3.25Å; I282-L286 PolarHBondContact O-N 2.89Å
283	K	88.8	Confident	82.2	Confident	115 Å²	115	75.9 Å²	75.9	50%	0.5	35%	0.353	S	S	.	.	I	π-helix	trans	-59.9	-46.8	-179.6	-178.4	-178.4	178.3	-176.6	0	111.8	W279 N280 F281 F287 S288	W279-K283 WeakPolarHBondContact O-CB 3.43Å; W279-K283 PolarHBondContact O-N 3.09Å; N280-K283 PolarHBondContact O-N 3.17Å; F281-K283 VanDerWaalsContact C-N 3.32Å; F281-K283 PolarHBondContact O-N 3.44Å; K283-F287 HydrophobicContact CB-CD2 4.25Å; K283-F287 HydrophobicContact CG-CD2 4.06Å; K283-F287 WeakPolarHBondContact O-CA 3.46Å; K283-F287 VanDerWaalsContact O-CB 3.31Å; K283-F287 WeakPolarHBondContact O-CB 3.41Å; K283-F287 PolarHBondContact O-N 3.48Å; K283-S288 PolarHBondContact O-N 2.87Å
284	F	85	Confident	81.1	Confident	51 Å²	51	77.9 Å²	77.9	22%	0.224	36%	0.357	C	S	.	.	I	π-helix	trans	-66.4	-45	-179.5	-177.1	-96	0	0	0	112.7	W54 L62 N280 F281 I282 S288	W54-F284 AromaticContact CH2-CE1 3.97Å; W54-F284 HydrophobicContact CH2-CE1 3.97Å; W54-F284 AromaticContact CH2-CE2 3.9Å; W54-F284 HydrophobicContact CH2-CE2 3.9Å; W54-F284 AromaticContact CH2-CZ 3.43Å; W54-F284 HydrophobicContact CH2-CZ 3.43Å; W54-F284 VanDerWaalsContact CH2-CZ 3.43Å; W54-F284 HydrophobicContact CZ2-CZ 4.41Å; W54-F284 AromaticContact CZ3-CE2 3.96Å; W54-F284 HydrophobicContact CZ3-CE2 3.96Å; W54-F284 AromaticContact CZ3-CZ 3.98Å; W54-F284 HydrophobicContact CZ3-CZ 3.98Å; L62-F284 HydrophobicContact CD1-CB 3.58Å; L62-F284 HydrophobicContact CD1-CD1 4.09Å; L62-F284 HydrophobicContact CD1-CG 3.86Å; L62-F284 HydrophobicContact CD2-CD1 3.98Å; L62-F284 HydrophobicContact CD2-CE1 4.23Å; L62-F284 HydrophobicContact CD2-CG 4.37Å; N280-F284 VanDerWaalsContact O-CB 3.28Å; N280-F284 WeakPolarHBondContact O-CB 3.37Å; N280-F284 PolarHBondContact O-N 3.5Å; F281-F284 PolarHBondContact O-N 3.5Å; I282-F284 PolarHBondContact O-N 2.93Å; F284-S288 WeakPolarHBondContact O-CB 3.37Å; F284-S288 PolarHBondContact O-N 3.42Å
285	N	81.3	Confident	80.2	Confident	46 Å²	46	71.8 Å²	71.8	25%	0.246	34%	0.344	C	S	.	.	I	π-helix	trans	-78.6	-36.9	-175	-75.3	-81.5	0	0	0	113.2	F281 I282	F281-N285 WeakPolarHBondContact CD2-ND2 3.48Å; F281-N285 WeakPolarHBondContact CE2-ND2 3.49Å; F281-N285 VanDerWaalsContact CZ-ND2 3.33Å; F281-N285 WeakPolarHBondContact CZ-ND2 3.13Å; F281-N285 WeakPolarHBondContact O-CB 3.29Å; F281-N285 PolarHBondContact O-N 3.12Å; F281-N285 PolarHBondContact O-ND2 2.85Å; I282-N285 PolarHBondContact O-N 3.28Å
286	L	76.7	Confident	79.9	Confident	117 Å²	117	75.3 Å²	75.3	61%	0.613	37%	0.366	S	S	*	.	I	π-helix	trans	-90.3	-40.5	-177.6	-63	-175.9	0	0	0	113.3	I282	I282-L286 HydrophobicContact CG2-CD1 3.72Å; I282-L286 HydrophobicContact CG2-CG 4.33Å; I282-L286 VanDerWaalsContact O-CB 3.31Å; I282-L286 WeakPolarHBondContact O-CB 3.25Å; I282-L286 PolarHBondContact O-N 2.89Å
287	F	77.2	Confident	79.6	Confident	153 Å²	153	75.5 Å²	75.5	67%	0.671	37%	0.366	S	S	*	.	I	π-helix	trans	-97.2	-38	-174.1	-57.4	-60.2	0	0	0	113.4	K283	K283-F287 HydrophobicContact CB-CD2 4.25Å; K283-F287 HydrophobicContact CG-CD2 4.06Å; K283-F287 WeakPolarHBondContact O-CA 3.46Å; K283-F287 VanDerWaalsContact O-CB 3.31Å; K283-F287 WeakPolarHBondContact O-CB 3.41Å; K283-F287 PolarHBondContact O-N 3.48Å
288	S	74.6	Confident	79.7	Confident	78 Å²	78	78.2 Å²	78.2	55%	0.545	38%	0.383	S	S	.	.	S	Bend	trans	-83.6	-14.5	-179.1	-48.7	0	0	0	0	113.2	K283 F284 G290	K283-S288 PolarHBondContact O-N 2.87Å; F284-S288 WeakPolarHBondContact O-CB 3.37Å; F284-S288 PolarHBondContact O-N 3.42Å; S288-G290 PolarHBondContact O-N 3.49Å
289	G	68.7	Low	79.7	Confident	20 Å²	20	86.1 Å²	86.1	21%	0.206	41%	0.413	C	S	.	.			trans	63.8	20.2	-178.4	0	0	0	0	0	114	S291 R292	G289-S291 PolarHBondContact O-N 3.45Å; G289-R292 PolarHBondContact O-N 3.35Å
290	G	64.5	Low	79.8	Confident	5 Å²	5	82.6 Å²	82.6	5%	0.052	40%	0.402	C	S	.	.	G	3₁₀ helix	trans	-57.7	-20.4	-173.6	0	0	0	0	0	114.4	S288 R292 F293	S288-G290 PolarHBondContact O-N 3.49Å; G290-R292 VanDerWaalsContact C-N 3.3Å; G290-R292 PolarHBondContact O-N 2.9Å; G290-F293 WeakPolarHBondContact O-CD2 3.24Å
291	S	63.3	Low	80	Confident	16 Å²	16	81.8 Å²	81.8	11%	0.112	40%	0.396	C	S	.	.	G	3₁₀ helix	trans	-66.6	-27.5	175.7	58.8	0	0	0	0	113.6	G289 F293 Y294 H377	G289-S291 PolarHBondContact O-N 3.45Å; S291-F293 PolarHBondContact O-N 3.01Å; S291-F293 VanDerWaalsContact O-N 3.16Å; S291-Y294 PolarHBondContact O-N 3.32Å; S291-H377 VanDerWaalsContact O-CB 3.25Å; S291-H377 WeakPolarHBondContact O-CB 3.42Å
292	R	63.2	Low	80.3	Confident	172 Å²	172	80.6 Å²	80.6	65%	0.649	39%	0.391	S	S	*	.	G	3₁₀ helix	trans	-65.8	-19.7	-176	-66.8	-175.5	-176.5	-172.5	1.9	114.1	G289 G290 Y294 P376	G289-R292 PolarHBondContact O-N 3.35Å; G290-R292 VanDerWaalsContact C-N 3.3Å; G290-R292 PolarHBondContact O-N 2.9Å; R292-Y294 PolarHBondContact O-N 3.47Å; R292-P376 HydrophobicContact CG-CB 4.06Å; R292-P376 HydrophobicContact CG-CG 4Å
293	F	65.1	Low	80.6	Confident	176 Å²	176	83.1 Å²	83.1	77%	0.772	41%	0.405	S	S	*	.	G	3₁₀ helix	trans	-74.1	-21.4	-175.9	-69.3	-76.9	0	0	0	114.4	G290 S291	G290-F293 WeakPolarHBondContact O-CD2 3.24Å; S291-F293 PolarHBondContact O-N 3.01Å; S291-F293 VanDerWaalsContact O-N 3.16Å
294	Y	67.9	Low	80.8	Confident	137 Å²	137	80 Å²	80	54%	0.537	40%	0.398	S	S	.	.	T	Hydrogen-bonded Turn	trans	-88.9	-40.1	-168.4	-66.7	-77.5	0	0	0	114	S291 R292	S291-Y294 PolarHBondContact O-N 3.32Å; R292-Y294 PolarHBondContact O-N 3.47Å
295	A	75.6	Confident	81.3	Confident	49 Å²	49	82.8 Å²	82.8	41%	0.405	41%	0.411	S	S	.	.			trans	174.7	146.7	170.6	0	0	0	0	0	107.7	H377	A295-H377 VanDerWaalsContact O-CA 3.3Å; A295-H377 WeakPolarHBondContact O-CA 3.37Å; A295-H377 PolarHBondContact O-ND1 2.89Å; A295-H377 VanDerWaalsContact O-ND1 3.11Å
296	V	83.5	Confident	81.9	Confident	92 Å²	92	80.6 Å²	80.6	56%	0.558	40%	0.4	S	S	*	.			trans	-115.3	132.2	173.9	-178.3	0	0	0	0	109.5	P376	V296-P376 WeakPolarHBondContact CA-O 3.36Å; V296-P376 HydrophobicContact CG1-CB 3.96Å; V296-P376 HydrophobicContact CG2-CB 3.99Å
297	Q	89.4	Confident	82.9	Confident	76 Å²	76	75.6 Å²	75.6	36%	0.355	37%	0.373	S	S	.	.			trans	-119.8	151	175.9	-71.4	-68.3	-7.7	0	0	109.4	W301 P376 K378	Q297-W301 HydrophobicContact CB-CB 3.98Å; Q297-W301 HydrophobicContact CB-CD2 4.37Å; Q297-W301 HydrophobicContact CB-CG 3.91Å; Q297-W301 HydrophobicContact CG-CD2 4.38Å; Q297-W301 HydrophobicContact CG-CG 4.23Å; Q297-P376 PolarHBondContact N-O 3.39Å; Q297-P376 VanDerWaalsContact N-O 3.07Å; Q297-K378 HydrophobicContact CB-CB 4.26Å; Q297-K378 HydrophobicContact CB-CD 3.91Å; Q297-K378 HydrophobicContact CB-CG 4.26Å; Q297-K378 PolarHBondContact O-NZ 3.14Å
298	P	93.1	Very high	83.8	Confident	58 Å²	58	71.5 Å²	71.5	38%	0.377	36%	0.358	S	S	.	.			trans	-59.3	154.8	179.3	26.1	-33.5	0	0	0	111	H300 W301 K378	P298-H300 PolarHBondContact O-N 3.32Å; P298-W301 HydrophobicContact CG-CB 4.2Å; P298-W301 WeakPolarHBondContact O-CB 3.44Å; P298-W301 PolarHBondContact O-N 3.45Å; P298-K378 VanDerWaalsContact O-CE 3.23Å; P298-K378 WeakPolarHBondContact O-CE 3.49Å; P298-K378 PolarHBondContact O-NZ 3.46Å
299	W	93.3	Very high	84.9	Confident	178 Å²	178	69.6 Å²	69.6	67%	0.674	35%	0.347	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.5	-37.7	-175.2	67.5	-92.7	0	0	0	112	W301 S373	W299-W301 PolarHBondContact O-N 3.37Å; W299-S373 WeakPolarHBondContact CA-O 2.81Å; W299-S373 WeakPolarHBondContact O-CB 3.38Å; W299-S373 PolarHBondContact O-OG 2.96Å
300	H	94.5	Very high	86.2	Confident	74 Å²	74	68.7 Å²	68.7	34%	0.343	34%	0.337	S	S	.	.	T	Hydrogen-bonded Turn	trans	-76.4	-3.9	-179.1	63.3	76.4	0	0	0	114.2	P298 Y302 L303 S304	P298-H300 PolarHBondContact O-N 3.32Å; H300-Y302 VanDerWaalsContact C-N 3.31Å; H300-Y302 PolarHBondContact O-N 3.45Å; H300-L303 PolarHBondContact O-N 3.35Å; H300-S304 PolarHBondContact ND1-OG 2.8Å; H300-S304 PolarHBondContact O-N 3.39Å; H300-S304 PolarHBondContact O-OG 3.1Å
301	W	96.5	Very high	87.8	Confident	21 Å²	21	68.5 Å²	68.5	8%	0.08	34%	0.335	C	S	.	.	H	α-helix	trans	-54.4	-43.4	-171	-178.9	86.2	0	0	0	113.3	Q297 P298 W299 L303 S304 Q305 G306 K378 F380	Q297-W301 HydrophobicContact CB-CB 3.98Å; Q297-W301 HydrophobicContact CB-CD2 4.37Å; Q297-W301 HydrophobicContact CB-CG 3.91Å; Q297-W301 HydrophobicContact CG-CD2 4.38Å; Q297-W301 HydrophobicContact CG-CG 4.23Å; P298-W301 HydrophobicContact CG-CB 4.2Å; P298-W301 WeakPolarHBondContact O-CB 3.44Å; P298-W301 PolarHBondContact O-N 3.45Å; W299-W301 PolarHBondContact O-N 3.37Å; W301-L303 VanDerWaalsContact C-N 3.31Å; W301-L303 PolarHBondContact O-N 3.09Å; W301-S304 PolarHBondContact O-N 3.22Å; W301-Q305 PolarHBondContact O-N 3.32Å; W301-G306 PolarHBondContact O-N 3.33Å; W301-K378 HydrophobicContact CB-CD 3.93Å; W301-K378 HydrophobicContact CD2-CD 4.49Å; W301-K378 HydrophobicContact CE3-CB 3.89Å; W301-K378 HydrophobicContact CE3-CD 4Å; W301-K378 HydrophobicContact CG-CD 4.5Å; W301-K378 HydrophobicContact CZ3-CB 4.12Å; W301-F380 AromaticContact CH2-CD1 3.75Å; W301-F380 HydrophobicContact CH2-CD1 3.75Å; W301-F380 HydrophobicContact CH2-CD2 4.31Å; W301-F380 AromaticContact CH2-CE1 3.51Å; W301-F380 HydrophobicContact CH2-CE1 3.51Å; W301-F380 HydrophobicContact CH2-CE2 4.06Å; W301-F380 HydrophobicContact CH2-CG 4.18Å; W301-F380 AromaticContact CH2-CZ 3.66Å; W301-F380 HydrophobicContact CH2-CZ 3.66Å; W301-F380 AromaticContact CZ2-CE1 3.93Å; W301-F380 HydrophobicContact CZ2-CE1 3.93Å; W301-F380 HydrophobicContact CZ2-CE2 4.33Å; W301-F380 AromaticContact CZ2-CZ 3.75Å; W301-F380 HydrophobicContact CZ2-CZ 3.75Å; W301-F380 HydrophobicContact CZ3-CD1 4.42Å; W301-F380 HydrophobicContact CZ3-CE1 4.45Å
302	Y	96.6	Very high	89.4	Confident	0 Å²	0	72.5 Å²	72.5	0%	0	35%	0.354	C	S	.	.	I	π-helix	trans	-61.3	-40	178.1	-80	-58.5	0	0	0	112.5	H300 F307 Y372 K378 E379 F382 I383	H300-Y302 VanDerWaalsContact C-N 3.31Å; H300-Y302 PolarHBondContact O-N 3.45Å; Y302-F307 WeakPolarHBondContact O-CB 3.26Å; Y302-F307 PolarHBondContact O-N 3.4Å; Y302-Y372 WeakPolarHBondContact CE2-O 3.26Å; Y302-K378 HydrophobicContact CD2-CD 3.7Å; Y302-K378 HydrophobicContact CD2-CG 4.16Å; Y302-K378 HydrophobicContact CE1-CB 4.41Å; Y302-K378 HydrophobicContact CE2-CB 3.73Å; Y302-K378 HydrophobicContact CE2-CD 3.62Å; Y302-K378 HydrophobicContact CE2-CG 3.53Å; Y302-K378 HydrophobicContact CG-CD 4.46Å; Y302-K378 WeakPolarHBondContact OH-CA 3.36Å; Y302-E379 WeakPolarHBondContact CE1-O 3.31Å; Y302-E379 PolarHBondContact OH-N 3.46Å; Y302-E379 PolarHBondContact OH-O 3.25Å; Y302-F382 WeakPolarHBondContact OH-CD2 3.29Å; Y302-I383 HydrophobicContact CD1-CD1 3.41Å; Y302-I383 VanDerWaalsContact CD1-CD1 3.41Å; Y302-I383 HydrophobicContact CD1-CG1 3.9Å; Y302-I383 HydrophobicContact CD1-CG2 4.01Å; Y302-I383 HydrophobicContact CE1-CB 4.41Å; Y302-I383 HydrophobicContact CE1-CD1 3.85Å; Y302-I383 HydrophobicContact CE1-CG1 3.78Å; Y302-I383 HydrophobicContact CE1-CG2 3.78Å; Y302-I383 HydrophobicContact CE2-CG2 4.35Å; Y302-I383 HydrophobicContact CG-CD1 4.23Å; Y302-I383 HydrophobicContact CG-CG2 4.35Å
303	L	93.8	Very high	90.9	Very high	112 Å²	112	69.1 Å²	69.1	59%	0.586	35%	0.353	S	S	*	.	I	π-helix	trans	-75.2	-44	179.7	-177.7	63.6	0	0	0	111.8	H300 W301	H300-L303 PolarHBondContact O-N 3.35Å; W301-L303 VanDerWaalsContact C-N 3.31Å; W301-L303 PolarHBondContact O-N 3.09Å
304	S	93.8	Very high	92.5	Very high	50 Å²	50	61.1 Å²	61.1	35%	0.35	32%	0.318	S	S	.	.	I	π-helix	trans	-80.9	-28.5	-172.7	58.2	0	0	0	0	114	H300 W301 L308	H300-S304 PolarHBondContact ND1-OG 2.8Å; H300-S304 PolarHBondContact O-N 3.39Å; H300-S304 PolarHBondContact O-OG 3.1Å; W301-S304 PolarHBondContact O-N 3.22Å; S304-L308 WeakPolarHBondContact O-CD1 3.36Å
305	Q	94.7	Very high	93.9	Very high	109 Å²	109	55.9 Å²	55.9	51%	0.509	30%	0.301	S	S	.	.	I	π-helix	trans	-138.2	-53.4	-171.4	-63.5	176.5	22.8	0	0	111.6	W301 L308 A309	W301-Q305 PolarHBondContact O-N 3.32Å; Q305-L308 PolarHBondContact O-N 3.01Å; Q305-A309 VanDerWaalsContact O-CB 3.28Å; Q305-A309 WeakPolarHBondContact O-CB 3.35Å; Q305-A309 PolarHBondContact O-N 3.22Å
306	G	94.5	Very high	94.9	Very high	0 Å²	0	57.5 Å²	57.5	0%	0	31%	0.307	C	S	.	.	I	π-helix	trans	-54.6	-61.7	-169.4	0	0	0	0	0	113.4	W301 A309 M310 F380	W301-G306 PolarHBondContact O-N 3.33Å; G306-A309 PolarHBondContact O-N 2.94Å; G306-M310 WeakPolarHBondContact O-CG 3.43Å; G306-M310 PolarHBondContact O-N 3.05Å; G306-M310 VanDerWaalsContact O-N 3.16Å; G306-F380 WeakPolarHBondContact O-CD1 3.22Å; G306-F380 VanDerWaalsContact O-CE1 3.31Å; G306-F380 WeakPolarHBondContact O-CE1 3.47Å
307	F	96.4	Very high	95.5	Very high	11 Å²	11	54.6 Å²	54.6	5%	0.048	29%	0.288	C	S	.	.	H	α-helix	trans	-69.6	-37.7	-177.1	-166.4	-129	0	0	0	112.2	Y302 A309 M310 L311 M365 I369 I383 S386 I387 A390	Y302-F307 WeakPolarHBondContact O-CB 3.26Å; Y302-F307 PolarHBondContact O-N 3.4Å; F307-A309 VanDerWaalsContact C-N 3.32Å; F307-A309 PolarHBondContact O-N 2.8Å; F307-M310 PolarHBondContact O-N 3.35Å; F307-L311 HydrophobicContact CD1-CD1 3.84Å; F307-L311 HydrophobicContact CE1-CD1 3.65Å; F307-L311 HydrophobicContact CE1-CG 4.39Å; F307-L311 HydrophobicContact CE2-CG 4.43Å; F307-L311 HydrophobicContact CG-CD1 4.39Å; F307-L311 HydrophobicContact CZ-CD1 4.05Å; F307-L311 HydrophobicContact CZ-CD2 4.41Å; F307-L311 HydrophobicContact CZ-CG 4.38Å; F307-L311 WeakPolarHBondContact O-CG 3.33Å; F307-L311 PolarHBondContact O-N 3.32Å; F307-M365 HydrophobicContact CE1-CE 4.5Å; F307-M365 HydrophobicContact CE1-CG 4.42Å; F307-M365 HydrophobicContact CE1-SD 3.79Å; F307-M365 HydrophobicContact CZ-CG 4.18Å; F307-M365 HydrophobicContact CZ-SD 3.68Å; F307-I369 HydrophobicContact CD1-CD1 3.89Å; F307-I369 HydrophobicContact CE1-CD1 4.06Å; F307-I369 HydrophobicContact CG-CD1 4.2Å; F307-I383 HydrophobicContact CB-CD1 3.94Å; F307-I383 HydrophobicContact CD2-CD1 3.73Å; F307-I383 HydrophobicContact CG-CD1 4.24Å; F307-S386 WeakPolarHBondContact CE2-OG 3.34Å; F307-I387 HydrophobicContact CD2-CD1 4.32Å; F307-I387 HydrophobicContact CE2-CD1 3.83Å; F307-A390 HydrophobicContact CE1-CB 4.45Å; F307-A390 HydrophobicContact CZ-CB 3.8Å
308	L	96.9	Very high	95.9	Very high	68 Å²	68	51.1 Å²	51.1	36%	0.356	27%	0.272	S	S	.	.	H	α-helix	trans	-62	-39.8	175.9	-57.6	-171.3	0	0	0	111.7	S304 Q305 L311 L312 T315	S304-L308 WeakPolarHBondContact O-CD1 3.36Å; Q305-L308 PolarHBondContact O-N 3.01Å; L308-L311 PolarHBondContact O-N 3.19Å; L308-L312 WeakPolarHBondContact O-CA 3.39Å; L308-L312 PolarHBondContact O-N 3.2Å; L308-T315 HydrophobicContact CD2-CG2 3.74Å; L308-T315 PolarHBondContact O-OG1 2.62Å
309	A	96.9	Very high	96.1	Very high	38 Å²	38	51.9 Å²	51.9	31%	0.314	28%	0.275	S	S	.	.	H	α-helix	trans	-67.2	-39.5	176.1	0	0	0	0	0	111.7	W132 Q305 G306 F307 L311 L312 F380	W132-A309 WeakPolarHBondContact CZ2-O 3.31Å; W132-A309 PolarHBondContact NE1-O 3.12Å; Q305-A309 VanDerWaalsContact O-CB 3.28Å; Q305-A309 WeakPolarHBondContact O-CB 3.35Å; Q305-A309 PolarHBondContact O-N 3.22Å; G306-A309 PolarHBondContact O-N 2.94Å; F307-A309 VanDerWaalsContact C-N 3.32Å; F307-A309 PolarHBondContact O-N 2.8Å; A309-L311 VanDerWaalsContact C-N 3.33Å; A309-L311 PolarHBondContact O-N 3.24Å; A309-L312 PolarHBondContact O-N 2.77Å; A309-F380 HydrophobicContact CB-CE1 3.95Å; A309-F380 HydrophobicContact CB-CZ 4.41Å
310	M	97.7	Very high	96.2	Very high	0 Å²	0	45.6 Å²	45.6	0%	0	26%	0.257	C	S	.	.	H	α-helix	trans	-64.7	-37.9	175.5	-65.4	166.5	64.3	0	0	112.1	N131 W132 F133 G306 F307 F380 I383 F384 I387	N131-M310 PolarHBondContact ND2-O 2.8Å; W132-M310 PolarHBondContact NE1-O 3.28Å; F133-M310 HydrophobicContact CB-CB 4.34Å; F133-M310 HydrophobicContact CD1-CB 4.37Å; F133-M310 HydrophobicContact CD1-CE 3.68Å; F133-M310 HydrophobicContact CD1-CG 4.13Å; F133-M310 HydrophobicContact CD2-CG 4.15Å; F133-M310 HydrophobicContact CE1-CE 3.46Å; F133-M310 VanDerWaalsContact CE1-CE 3.46Å; F133-M310 HydrophobicContact CE1-CG 4.29Å; F133-M310 HydrophobicContact CE1-SD 4.41Å; F133-M310 HydrophobicContact CE2-CG 4.31Å; F133-M310 HydrophobicContact CG-CB 4.21Å; F133-M310 HydrophobicContact CG-CG 4.05Å; F133-M310 HydrophobicContact CZ-CE 4.15Å; F133-M310 HydrophobicContact CZ-CG 4.37Å; G306-M310 WeakPolarHBondContact O-CG 3.43Å; G306-M310 PolarHBondContact O-N 3.05Å; G306-M310 VanDerWaalsContact O-N 3.16Å; F307-M310 PolarHBondContact O-N 3.35Å; M310-F380 WeakPolarHBondContact CE-O 3.36Å; M310-F380 HydrophobicContact CG-CB 4.04Å; M310-F380 HydrophobicContact CG-CD1 3.57Å; M310-F380 HydrophobicContact CG-CE1 4.39Å; M310-F380 HydrophobicContact CG-CG 4.18Å; M310-F380 HydrophobicContact SD-CB 3.79Å; M310-F380 HydrophobicContact SD-CD1 3.82Å; M310-F380 HydrophobicContact SD-CG 4.31Å; M310-I383 HydrophobicContact CE-CD1 4.48Å; M310-I383 HydrophobicContact CE-CG1 3.98Å; M310-I383 HydrophobicContact SD-CD1 3.72Å; M310-I383 HydrophobicContact SD-CG1 3.63Å; M310-F384 HydrophobicContact CE-CB 4.45Å; M310-F384 HydrophobicContact CE-CD2 4.35Å; M310-I387 HydrophobicContact CB-CD1 3.79Å; M310-I387 HydrophobicContact CE-CD1 3.82Å; M310-I387 HydrophobicContact CE-CG1 3.61Å
311	L	97.6	Very high	96.3	Very high	2 Å²	2	42.1 Å²	42.1	1%	0.01	24%	0.24	C	C	.	.	H	α-helix	trans	-77.5	-35.5	177.4	-66.8	178.7	0	0	0	112.9	F307 L308 A309 T313 Q314 T315 V318 I387 A390 M391	F307-L311 HydrophobicContact CD1-CD1 3.84Å; F307-L311 HydrophobicContact CE1-CD1 3.65Å; F307-L311 HydrophobicContact CE1-CG 4.39Å; F307-L311 HydrophobicContact CE2-CG 4.43Å; F307-L311 HydrophobicContact CG-CD1 4.39Å; F307-L311 HydrophobicContact CZ-CD1 4.05Å; F307-L311 HydrophobicContact CZ-CD2 4.41Å; F307-L311 HydrophobicContact CZ-CG 4.38Å; F307-L311 WeakPolarHBondContact O-CG 3.33Å; F307-L311 PolarHBondContact O-N 3.32Å; L308-L311 PolarHBondContact O-N 3.19Å; A309-L311 VanDerWaalsContact C-N 3.33Å; A309-L311 PolarHBondContact O-N 3.24Å; L311-T313 PolarHBondContact O-N 3.31Å; L311-Q314 PolarHBondContact O-N 3.04Å; L311-Q314 PolarHBondContact O-OE1 3.35Å; L311-T315 WeakPolarHBondContact CB-OG1 2.96Å; L311-V318 HydrophobicContact CD1-CB 4.16Å; L311-V318 HydrophobicContact CD1-CG1 4.17Å; L311-V318 HydrophobicContact CD1-CG2 3.99Å; L311-V318 HydrophobicContact CD2-CG2 4.36Å; L311-I387 HydrophobicContact CD2-CD1 3.77Å; L311-I387 HydrophobicContact CG-CD1 4.39Å; L311-A390 HydrophobicContact CD1-CB 4.49Å; L311-A390 HydrophobicContact CD2-CB 3.72Å; L311-M391 HydrophobicContact CD2-CE 3.3Å
312	L	96	Very high	96.3	Very high	99 Å²	99	43.5 Å²	43.5	52%	0.518	25%	0.249	S	C	.	.	G	3₁₀ helix	trans	43.2	-104.5	-178.2	-167.5	67.6	0	0	0	112.5	W132 L308 A309 Q314 T315	W132-L312 HydrophobicContact CG-CD2 4.29Å; L308-L312 WeakPolarHBondContact O-CA 3.39Å; L308-L312 PolarHBondContact O-N 3.2Å; A309-L312 PolarHBondContact O-N 2.77Å; L312-Q314 VanDerWaalsContact C-N 3.27Å; L312-Q314 PolarHBondContact O-N 3.29Å; L312-T315 VanDerWaalsContact O-CB 3.22Å; L312-T315 WeakPolarHBondContact O-CB 3.2Å; L312-T315 PolarHBondContact O-N 3.21Å; L312-T315 VanDerWaalsContact O-N 3.13Å; L312-T315 PolarHBondContact O-OG1 3.43Å
313	T	95.5	Very high	96.3	Very high	101 Å²	101	47.8 Å²	47.8	62%	0.62	28%	0.275	S	S	*	.	G	3₁₀ helix	trans	-68.5	-22.1	-177.5	54.7	0	0	0	0	113.5	L311 P316	L311-T313 PolarHBondContact O-N 3.31Å; T313-P316 WeakPolarHBondContact O-CD 3.38Å
314	Q	97.7	Very high	96.2	Very high	9 Å²	9	43 Å²	43	4%	0.042	25%	0.249	C	C	.	.	G	3₁₀ helix	trans	-83.1	-11.1	174.8	-69.6	85.7	21.8	0	0	113.2	H127 N131 L311 L312 L317 V318 M391	H127-Q314 HydrophobicContact CB-CG 4.36Å; N131-Q314 PolarHBondContact ND2-OE1 3.26Å; L311-Q314 PolarHBondContact O-N 3.04Å; L311-Q314 PolarHBondContact O-OE1 3.35Å; L312-Q314 VanDerWaalsContact C-N 3.27Å; L312-Q314 PolarHBondContact O-N 3.29Å; Q314-L317 WeakPolarHBondContact O-CB 3.27Å; Q314-L317 PolarHBondContact O-N 2.81Å; Q314-L317 VanDerWaalsContact O-N 3.12Å; Q314-V318 WeakPolarHBondContact O-CG2 3.31Å; Q314-V318 PolarHBondContact O-N 3.2Å; Q314-V318 VanDerWaalsContact O-N 3.11Å; Q314-M391 HydrophobicContact CB-CE 3.85Å; Q314-M391 HydrophobicContact CB-SD 4.46Å; Q314-M391 HydrophobicContact CG-CE 3.98Å; Q314-M391 HydrophobicContact CG-SD 3.97Å
315	T	97.2	Very high	96.1	Very high	27 Å²	27	40.9 Å²	40.9	17%	0.166	23%	0.234	C	C	.	.	H	α-helix	trans	-52.3	-50.2	-178.4	-62.6	0	0	0	0	113.3	L308 L311 L312 L317 V318 V319	L308-T315 HydrophobicContact CD2-CG2 3.74Å; L308-T315 PolarHBondContact O-OG1 2.62Å; L311-T315 WeakPolarHBondContact CB-OG1 2.96Å; L312-T315 VanDerWaalsContact O-CB 3.22Å; L312-T315 WeakPolarHBondContact O-CB 3.2Å; L312-T315 PolarHBondContact O-N 3.21Å; L312-T315 VanDerWaalsContact O-N 3.13Å; L312-T315 PolarHBondContact O-OG1 3.43Å; T315-L317 PolarHBondContact O-N 3.14Å; T315-V318 PolarHBondContact O-N 3.44Å; T315-V319 HydrophobicContact CG2-CG2 4.2Å; T315-V319 WeakPolarHBondContact O-CG2 3.24Å; T315-V319 PolarHBondContact O-N 3.5Å
316	P	97	Very high	96	Very high	82 Å²	82	41.5 Å²	41.5	53%	0.532	24%	0.235	S	C	.	.	H	α-helix	trans	-61.5	-34	-178.7	-22.8	35.2	0	0	0	112.8	T313 T320	T313-P316 WeakPolarHBondContact O-CD 3.38Å; P316-T320 WeakPolarHBondContact O-CB 3.44Å; P316-T320 PolarHBondContact O-N 2.97Å; P316-T320 PolarHBondContact O-OG1 2.97Å
317	L	97.4	Very high	95.8	Very high	31 Å²	31	48.2 Å²	48.2	16%	0.162	26%	0.264	C	S	.	.	H	α-helix	trans	-69.7	-44.7	179.4	-56.1	176.6	0	0	0	111.2	H127 Q314 T315 T320 F321 I397 F401	H127-L317 WeakPolarHBondContact CE1-CD1 3.3Å; Q314-L317 WeakPolarHBondContact O-CB 3.27Å; Q314-L317 PolarHBondContact O-N 2.81Å; Q314-L317 VanDerWaalsContact O-N 3.12Å; T315-L317 PolarHBondContact O-N 3.14Å; L317-T320 PolarHBondContact O-N 3.4Å; L317-F321 PolarHBondContact O-N 3.42Å; L317-I397 HydrophobicContact CB-CG2 4.39Å; L317-I397 HydrophobicContact CD2-CG2 3.81Å; L317-F401 HydrophobicContact CD2-CD2 4.39Å; L317-F401 HydrophobicContact CD2-CE2 4.02Å
318	V	97.7	Very high	95.3	Very high	4 Å²	4	50.1 Å²	50.1	2%	0.024	27%	0.272	C	S	.	.	H	α-helix	trans	-63.5	-45.5	177.4	176.4	0	0	0	0	110.9	L311 Q314 T315 F321 I322 A390 F393 S394	L311-V318 HydrophobicContact CD1-CB 4.16Å; L311-V318 HydrophobicContact CD1-CG1 4.17Å; L311-V318 HydrophobicContact CD1-CG2 3.99Å; L311-V318 HydrophobicContact CD2-CG2 4.36Å; Q314-V318 WeakPolarHBondContact O-CG2 3.31Å; Q314-V318 PolarHBondContact O-N 3.2Å; Q314-V318 VanDerWaalsContact O-N 3.11Å; T315-V318 PolarHBondContact O-N 3.44Å; V318-F321 WeakPolarHBondContact O-CB 3.45Å; V318-F321 PolarHBondContact O-N 3.04Å; V318-I322 HydrophobicContact CG1-CD1 4.06Å; V318-I322 WeakPolarHBondContact O-CG1 3.49Å; V318-I322 PolarHBondContact O-N 3.29Å; V318-A390 HydrophobicContact CG1-CB 4.37Å; V318-A390 HydrophobicContact CG2-CB 3.98Å; V318-A390 WeakPolarHBondContact CG2-O 3.42Å; V318-F393 HydrophobicContact CG1-CD2 4.3Å; V318-S394 WeakPolarHBondContact CG2-OG 3.43Å
319	V	96.4	Very high	94.8	Very high	73 Å²	73	47.8 Å²	47.8	44%	0.442	26%	0.264	S	S	.	.	H	α-helix	trans	-63.5	-45	177.3	173.3	0	0	0	0	110.9	T315 F321 I322 V323	T315-V319 HydrophobicContact CG2-CG2 4.2Å; T315-V319 WeakPolarHBondContact O-CG2 3.24Å; T315-V319 PolarHBondContact O-N 3.5Å; V319-F321 VanDerWaalsContact C-N 3.28Å; V319-F321 PolarHBondContact O-N 3.48Å; V319-I322 PolarHBondContact O-N 3.45Å; V319-V323 HydrophobicContact CG1-CG2 4.36Å; V319-V323 WeakPolarHBondContact O-CG2 3.35Å; V319-V323 PolarHBondContact O-N 3.47Å
320	T	96	Very high	94.1	Very high	47 Å²	47	46.5 Å²	46.5	29%	0.288	25%	0.253	S	S	.	.	H	α-helix	trans	-58.2	-42.9	176.7	-60.2	0	0	0	0	110.9	P316 L317 V323 M324 I397	P316-T320 WeakPolarHBondContact O-CB 3.44Å; P316-T320 PolarHBondContact O-N 2.97Å; P316-T320 PolarHBondContact O-OG1 2.97Å; L317-T320 PolarHBondContact O-N 3.4Å; T320-V323 PolarHBondContact O-N 3.12Å; T320-M324 HydrophobicContact CG2-CG 4.29Å; T320-M324 HydrophobicContact CG2-SD 3.84Å; T320-M324 WeakPolarHBondContact O-CB 3.46Å; T320-M324 VanDerWaalsContact O-CG 3.26Å; T320-M324 WeakPolarHBondContact O-CG 3.25Å; T320-M324 PolarHBondContact O-N 3.41Å; T320-I397 HydrophobicContact CG2-CD1 4.11Å; T320-I397 HydrophobicContact CG2-CG2 4.28Å
321	F	96.9	Very high	93.3	Very high	0 Å²	0	47.7 Å²	47.7	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-59.1	-51.8	175.3	179.7	-98	0	0	0	112.3	L317 V318 V319 V323 M324 Y325 F332 V333 C358 I362 F393 I396 I397	L317-F321 PolarHBondContact O-N 3.42Å; V318-F321 WeakPolarHBondContact O-CB 3.45Å; V318-F321 PolarHBondContact O-N 3.04Å; V319-F321 VanDerWaalsContact C-N 3.28Å; V319-F321 PolarHBondContact O-N 3.48Å; F321-V323 VanDerWaalsContact C-N 3.31Å; F321-V323 PolarHBondContact O-N 3.46Å; F321-M324 PolarHBondContact O-N 3.02Å; F321-Y325 HydrophobicContact CE1-CD2 4.36Å; F321-Y325 HydrophobicContact CE1-CG 4.47Å; F321-Y325 AromaticContact CZ-CD2 3.91Å; F321-Y325 HydrophobicContact CZ-CD2 3.91Å; F321-Y325 HydrophobicContact CZ-CG 4.42Å; F321-Y325 VanDerWaalsContact O-CB 3.3Å; F321-Y325 WeakPolarHBondContact O-CB 3.5Å; F321-Y325 PolarHBondContact O-N 2.8Å; F321-F332 AromaticContact CD2-CZ 3.81Å; F321-F332 HydrophobicContact CD2-CZ 3.81Å; F321-F332 HydrophobicContact CE2-CE1 4.28Å; F321-F332 AromaticContact CE2-CZ 3.63Å; F321-F332 HydrophobicContact CE2-CZ 3.63Å; F321-V333 HydrophobicContact CE2-CG2 3.98Å; F321-V333 HydrophobicContact CZ-CG2 4.44Å; F321-C358 HydrophobicContact CE1-CB 4.4Å; F321-C358 HydrophobicContact CZ-CB 3.76Å; F321-I362 HydrophobicContact CE1-CD1 3.96Å; F321-I362 HydrophobicContact CE1-CG1 4.31Å; F321-F393 HydrophobicContact CB-CB 3.75Å; F321-F393 HydrophobicContact CB-CG 4.49Å; F321-F393 HydrophobicContact CD1-CB 3.49Å; F321-F393 VanDerWaalsContact CD1-CB 3.49Å; F321-F393 AromaticContact CD1-CD1 3.4Å; F321-F393 HydrophobicContact CD1-CD1 3.4Å; F321-F393 AromaticContact CD1-CD2 3.89Å; F321-F393 HydrophobicContact CD1-CD2 3.89Å; F321-F393 HydrophobicContact CD1-CE1 4.08Å; F321-F393 AromaticContact CD1-CG 3.3Å; F321-F393 HydrophobicContact CD1-CG 3.3Å; F321-F393 HydrophobicContact CD2-CB 4.25Å; F321-F393 HydrophobicContact CE1-CB 4.18Å; F321-F393 AromaticContact CE1-CD1 3.14Å; F321-F393 HydrophobicContact CE1-CD1 3.14Å; F321-F393 HydrophobicContact CE1-CD2 4.27Å; F321-F393 AromaticContact CE1-CE1 3.48Å; F321-F393 HydrophobicContact CE1-CE1 3.48Å; F321-F393 VanDerWaalsContact CE1-CE1 3.48Å; F321-F393 AromaticContact CE1-CG 3.6Å; F321-F393 HydrophobicContact CE1-CG 3.6Å; F321-F393 HydrophobicContact CE1-CZ 4.17Å; F321-F393 HydrophobicContact CE2-CD1 4.36Å; F321-F393 HydrophobicContact CG-CB 3.54Å; F321-F393 HydrophobicContact CG-CD1 4.11Å; F321-F393 AromaticContact CG-CG 3.91Å; F321-F393 HydrophobicContact CG-CG 3.91Å; F321-F393 AromaticContact CZ-CD1 3.71Å; F321-F393 HydrophobicContact CZ-CD1 3.71Å; F321-F393 HydrophobicContact CZ-CE1 4.11Å; F321-F393 HydrophobicContact CZ-CG 4.44Å; F321-I396 HydrophobicContact CD2-CB 4.1Å; F321-I396 HydrophobicContact CD2-CD1 4.21Å; F321-I396 HydrophobicContact CD2-CG2 3.95Å; F321-I396 HydrophobicContact CE2-CB 4.11Å; F321-I396 HydrophobicContact CE2-CD1 3.49Å; F321-I396 VanDerWaalsContact CE2-CD1 3.49Å; F321-I396 HydrophobicContact CE2-CG1 4.41Å; F321-I396 HydrophobicContact CE2-CG2 3.83Å; F321-I396 HydrophobicContact CZ-CD1 3.95Å; F321-I397 HydrophobicContact CB-CD1 4.16Å; F321-I397 HydrophobicContact CB-CG1 3.6Å; F321-I397 HydrophobicContact CD2-CD1 4.3Å; F321-I397 HydrophobicContact CD2-CG1 4.15Å; F321-I397 HydrophobicContact CG-CG1 4.39Å
322	I	95.9	Very high	92.7	Very high	51 Å²	51	48 Å²	48	26%	0.262	27%	0.266	S	S	.	.	H	α-helix	trans	-58	-47.7	-178.5	-67.8	168.6	0	0	0	109.8	V318 V319 M324 Y325 F326 M365	V318-I322 HydrophobicContact CG1-CD1 4.06Å; V318-I322 WeakPolarHBondContact O-CG1 3.49Å; V318-I322 PolarHBondContact O-N 3.29Å; V319-I322 PolarHBondContact O-N 3.45Å; I322-M324 PolarHBondContact O-N 3.44Å; I322-Y325 PolarHBondContact O-N 2.91Å; I322-F326 HydrophobicContact CG2-CD2 3.8Å; I322-F326 HydrophobicContact CG2-CE2 3.88Å; I322-F326 VanDerWaalsContact O-CD2 3.28Å; I322-F326 WeakPolarHBondContact O-CD2 3.24Å; I322-F326 PolarHBondContact O-N 3.33Å; I322-M365 HydrophobicContact CD1-CE 4.1Å
323	V	95.4	Very high	92.2	Very high	89 Å²	89	43.2 Å²	43.2	54%	0.539	24%	0.241	S	C	.	.	H	α-helix	trans	-60.6	-46.5	177.9	172.5	0	0	0	0	111.5	V319 T320 F321 Y325 K327	V319-V323 HydrophobicContact CG1-CG2 4.36Å; V319-V323 WeakPolarHBondContact O-CG2 3.35Å; V319-V323 PolarHBondContact O-N 3.47Å; T320-V323 PolarHBondContact O-N 3.12Å; F321-V323 VanDerWaalsContact C-N 3.31Å; F321-V323 PolarHBondContact O-N 3.46Å; V323-Y325 VanDerWaalsContact C-N 3.35Å; V323-Y325 PolarHBondContact O-N 2.94Å; V323-K327 WeakPolarHBondContact O-CB 3.17Å; V323-K327 PolarHBondContact O-N 3.1Å
324	M	92.7	Very high	91.4	Very high	11 Å²	11	40.7 Å²	40.7	5%	0.054	22%	0.22	C	C	.	.	H	α-helix	trans	-66.1	-36.6	178.7	-73.3	-176.4	68.2	0	0	112.6	T320 F321 I322 K327 Y328 F332 I397 W400	T320-M324 HydrophobicContact CG2-CG 4.29Å; T320-M324 HydrophobicContact CG2-SD 3.84Å; T320-M324 WeakPolarHBondContact O-CB 3.46Å; T320-M324 VanDerWaalsContact O-CG 3.26Å; T320-M324 WeakPolarHBondContact O-CG 3.25Å; T320-M324 PolarHBondContact O-N 3.41Å; F321-M324 PolarHBondContact O-N 3.02Å; I322-M324 PolarHBondContact O-N 3.44Å; M324-K327 PolarHBondContact O-N 3.09Å; M324-Y328 HydrophobicContact CB-CD2 4.09Å; M324-Y328 HydrophobicContact CB-CE2 4.44Å; M324-Y328 HydrophobicContact CE-CD2 4.38Å; M324-Y328 HydrophobicContact CE-CE2 4.35Å; M324-Y328 HydrophobicContact CG-CD2 4.31Å; M324-Y328 HydrophobicContact CG-CE2 4.17Å; M324-Y328 WeakPolarHBondContact O-CB 3.45Å; M324-Y328 WeakPolarHBondContact O-CD2 3.43Å; M324-Y328 PolarHBondContact O-N 3.21Å; M324-F332 HydrophobicContact CB-CD1 4.47Å; M324-F332 HydrophobicContact CB-CE1 4.05Å; M324-F332 HydrophobicContact CB-CE2 4.38Å; M324-F332 HydrophobicContact CB-CZ 3.97Å; M324-F332 HydrophobicContact CE-CD2 4.02Å; M324-F332 HydrophobicContact CE-CE2 4.1Å; M324-I397 HydrophobicContact SD-CD1 3.7Å; M324-W400 HydrophobicContact CE-CD2 4.01Å; M324-W400 HydrophobicContact CE-CG 4.26Å; M324-W400 HydrophobicContact CE-CZ2 4.02Å
325	Y	92.3	Very high	90.5	Very high	6 Å²	6	41.3 Å²	41.3	2%	0.024	22%	0.223	C	C	.	.	H	α-helix	trans	-65.7	-47.4	177.8	-171.6	-89.8	0	0	0	112	F321 I322 V323 K327 G329 P330 F332 M353 D356 C358 G359 I362	F321-Y325 HydrophobicContact CE1-CD2 4.36Å; F321-Y325 HydrophobicContact CE1-CG 4.47Å; F321-Y325 AromaticContact CZ-CD2 3.91Å; F321-Y325 HydrophobicContact CZ-CD2 3.91Å; F321-Y325 HydrophobicContact CZ-CG 4.42Å; F321-Y325 VanDerWaalsContact O-CB 3.3Å; F321-Y325 WeakPolarHBondContact O-CB 3.5Å; F321-Y325 PolarHBondContact O-N 2.8Å; I322-Y325 PolarHBondContact O-N 2.91Å; V323-Y325 VanDerWaalsContact C-N 3.35Å; V323-Y325 PolarHBondContact O-N 2.94Å; Y325-K327 VanDerWaalsContact C-N 3.32Å; Y325-K327 PolarHBondContact O-N 3.13Å; Y325-G329 WeakPolarHBondContact O-CA 3.39Å; Y325-G329 PolarHBondContact O-N 3.11Å; Y325-P330 HydrophobicContact CE2-CB 3.91Å; Y325-F332 HydrophobicContact CD2-CE1 4.18Å; Y325-M353 HydrophobicContact CE1-CE 4.35Å; Y325-M353 HydrophobicContact CE1-CG 4.19Å; Y325-D356 VanDerWaalsContact CE2-OD2 3.25Å; Y325-D356 WeakPolarHBondContact CE2-OD2 3.49Å; Y325-D356 PolarHBondContact OH-OD2 3.19Å; Y325-C358 HydrophobicContact CD2-CB 4.3Å; Y325-C358 HydrophobicContact CE2-CB 3.83Å; Y325-G359 WeakPolarHBondContact OH-CA 3.49Å; Y325-G359 PolarHBondContact OH-N 2.8Å; Y325-I362 HydrophobicContact CD1-CD1 3.47Å; Y325-I362 VanDerWaalsContact CD1-CD1 3.47Å; Y325-I362 HydrophobicContact CD2-CD1 4.34Å; Y325-I362 HydrophobicContact CE1-CD1 3.81Å; Y325-I362 HydrophobicContact CG-CD1 3.77Å
326	F	91.9	Very high	89.9	Confident	122 Å²	122	40 Å²	40	54%	0.535	22%	0.216	S	C	.	.	H	α-helix	trans	-70.4	-28.8	176.5	-78	-72.2	0	0	0	113	I322 M353	I322-F326 HydrophobicContact CG2-CD2 3.8Å; I322-F326 HydrophobicContact CG2-CE2 3.88Å; I322-F326 VanDerWaalsContact O-CD2 3.28Å; I322-F326 WeakPolarHBondContact O-CD2 3.24Å; I322-F326 PolarHBondContact O-N 3.33Å; F326-M353 HydrophobicContact CE1-CE 4.02Å; F326-M353 HydrophobicContact CE1-SD 3.99Å; F326-M353 HydrophobicContact CZ-CE 3.86Å; F326-M353 HydrophobicContact CZ-SD 4.44Å
327	K	90.5	Very high	89	Confident	141 Å²	141	36.3 Å²	36.3	61%	0.613	19%	0.192	S	C	*	.	H	α-helix	trans	-79.6	-41.1	179.2	-173.9	172.7	-179.1	177.1	0	113.9	V323 M324 Y325	V323-K327 WeakPolarHBondContact O-CB 3.17Å; V323-K327 PolarHBondContact O-N 3.1Å; M324-K327 PolarHBondContact O-N 3.09Å; Y325-K327 VanDerWaalsContact C-N 3.32Å; Y325-K327 PolarHBondContact O-N 3.13Å
328	Y	86.5	Confident	87.9	Confident	51 Å²	51	41.4 Å²	41.4	20%	0.2	21%	0.214	C	C	.	.	H	α-helix	trans	-113.2	-6.1	-171.6	-55.6	-64.8	0	0	0	113.6	M324 L411 I415	M324-Y328 HydrophobicContact CB-CD2 4.09Å; M324-Y328 HydrophobicContact CB-CE2 4.44Å; M324-Y328 HydrophobicContact CE-CD2 4.38Å; M324-Y328 HydrophobicContact CE-CE2 4.35Å; M324-Y328 HydrophobicContact CG-CD2 4.31Å; M324-Y328 HydrophobicContact CG-CE2 4.17Å; M324-Y328 WeakPolarHBondContact O-CB 3.45Å; M324-Y328 WeakPolarHBondContact O-CD2 3.43Å; M324-Y328 PolarHBondContact O-N 3.21Å; Y328-L411 HydrophobicContact CD1-CD2 3.57Å; Y328-L411 HydrophobicContact CD2-CD2 3.62Å; Y328-L411 HydrophobicContact CE1-CD2 3.74Å; Y328-L411 HydrophobicContact CE2-CD2 3.78Å; Y328-L411 HydrophobicContact CG-CD2 3.51Å; Y328-I415 HydrophobicContact CD1-CD1 3.86Å; Y328-I415 HydrophobicContact CG-CD1 4.4Å
329	G	84.8	Confident	86.6	Confident	19 Å²	19	45.3 Å²	45.3	20%	0.196	23%	0.232	C	C	.	.			trans	69.1	-180	-175.7	0	0	0	0	0	113.3	Y325 G331 F332	Y325-G329 WeakPolarHBondContact O-CA 3.39Å; Y325-G329 PolarHBondContact O-N 3.11Å; G329-G331 PolarHBondContact O-N 3.03Å; G329-F332 WeakPolarHBondContact O-CD1 3.45Å; G329-F332 PolarHBondContact O-N 2.81Å
330	P	83.5	Confident	85.4	Confident	12 Å²	12	42 Å²	42	8%	0.078	21%	0.212	C	C	.	.	T	Hydrogen-bonded Turn	trans	-65.7	-13.2	-178.4	28	-36	0	0	0	113.7	Y325 F332 V333 R334 Q352 D356	Y325-P330 HydrophobicContact CE2-CB 3.91Å; P330-F332 VanDerWaalsContact C-N 3.25Å; P330-F332 PolarHBondContact O-N 2.83Å; P330-V333 PolarHBondContact O-N 2.75Å; P330-R334 PolarHBondContact O-N 2.93Å; P330-Q352 VanDerWaalsContact CD-CD 3.49Å; P330-Q352 HydrophobicContact CG-CG 3.71Å; P330-D356 HydrophobicContact CB-CB 3.95Å; P330-D356 VanDerWaalsContact CB-CG 3.48Å; P330-D356 HydrophobicContact CG-CB 4.38Å
331	G	80.1	Confident	84.2	Confident	24 Å²	24	45.2 Å²	45.2	25%	0.247	22%	0.222	C	C	.	.	H	α-helix	trans	-58.2	-33.8	176.6	0	0	0	0	0	113.4	G329 V333 R334	G329-G331 PolarHBondContact O-N 3.03Å; G331-V333 VanDerWaalsContact C-N 3.31Å; G331-V333 PolarHBondContact O-N 3.16Å; G331-R334 WeakPolarHBondContact O-CB 3.22Å; G331-R334 PolarHBondContact O-N 3.48Å
332	F	84.8	Confident	82.8	Confident	8 Å²	8	53.4 Å²	53.4	4%	0.035	26%	0.258	C	S	.	.	H	α-helix	trans	-66.4	-35.6	179.1	95.1	-98.6	0	0	0	111.8	F321 M324 Y325 G329 P330 R334 L336 I396 L411	F321-F332 AromaticContact CD2-CZ 3.81Å; F321-F332 HydrophobicContact CD2-CZ 3.81Å; F321-F332 HydrophobicContact CE2-CE1 4.28Å; F321-F332 AromaticContact CE2-CZ 3.63Å; F321-F332 HydrophobicContact CE2-CZ 3.63Å; M324-F332 HydrophobicContact CB-CD1 4.47Å; M324-F332 HydrophobicContact CB-CE1 4.05Å; M324-F332 HydrophobicContact CB-CE2 4.38Å; M324-F332 HydrophobicContact CB-CZ 3.97Å; M324-F332 HydrophobicContact CE-CD2 4.02Å; M324-F332 HydrophobicContact CE-CE2 4.1Å; Y325-F332 HydrophobicContact CD2-CE1 4.18Å; G329-F332 WeakPolarHBondContact O-CD1 3.45Å; G329-F332 PolarHBondContact O-N 2.81Å; P330-F332 VanDerWaalsContact C-N 3.25Å; P330-F332 PolarHBondContact O-N 2.83Å; F332-R334 VanDerWaalsContact C-N 3.34Å; F332-L336 HydrophobicContact CE2-CD1 4.41Å; F332-I396 HydrophobicContact CE2-CG2 4.24Å; F332-L411 HydrophobicContact CB-CD2 4.39Å
333	V	85.2	Confident	81.3	Confident	0 Å²	0	52.5 Å²	52.5	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-72	-33.8	178.6	-168.2	0	0	0	0	110.2	F321 P330 G331 D335 L336 R340 I396	F321-V333 HydrophobicContact CE2-CG2 3.98Å; F321-V333 HydrophobicContact CZ-CG2 4.44Å; P330-V333 PolarHBondContact O-N 2.75Å; G331-V333 VanDerWaalsContact C-N 3.31Å; G331-V333 PolarHBondContact O-N 3.16Å; V333-D335 PolarHBondContact O-N 3.12Å; V333-L336 WeakPolarHBondContact O-CB 3.17Å; V333-L336 PolarHBondContact O-N 3.23Å; V333-L336 VanDerWaalsContact O-N 3.16Å; V333-R340 VanDerWaalsContact CG1-CZ 3.48Å; V333-R340 WeakPolarHBondContact O-CD 3.15Å; V333-I396 HydrophobicContact CG1-CD1 4.01Å; V333-I396 HydrophobicContact CG1-CG1 4.37Å; V333-I396 HydrophobicContact CG1-CG2 4.05Å; V333-I396 HydrophobicContact CG2-CG2 4.41Å
334	R	79.5	Confident	79.7	Confident	48 Å²	48	52.4 Å²	52.4	18%	0.181	25%	0.25	C	C	.	.	H	α-helix	trans	-58.6	-35.6	179.1	-171.7	175.8	64.9	-172.5	-3.2	112.7	P330 G331 F332 L336 K341 R418	P330-R334 PolarHBondContact O-N 2.93Å; G331-R334 WeakPolarHBondContact O-CB 3.22Å; G331-R334 PolarHBondContact O-N 3.48Å; F332-R334 VanDerWaalsContact C-N 3.34Å; R334-L336 VanDerWaalsContact C-N 3.25Å; R334-L336 PolarHBondContact O-N 2.94Å; R334-K341 HydrophobicContact CG-CG 4.47Å; R334-K341 VanDerWaalsContact O-CG 3.26Å; R334-K341 WeakPolarHBondContact O-CG 3.43Å; R334-R418 VanDerWaalsContact NH2-NH1 3.17Å
335	D	79	Confident	78.4	Confident	21 Å²	21	52.8 Å²	52.8	11%	0.112	25%	0.251	C	S	.	.	T	Hydrogen-bonded Turn	trans	-79.3	-8.1	-176.6	-64.2	-35.8	0	0	0	113.2	V333 R418	V333-D335 PolarHBondContact O-N 3.12Å; D335-R418 IonicContact OD1-CZ 3.83Å; D335-R418 IonicContact OD1-NH1 2.93Å; D335-R418 PolarHBondContact OD1-NH1 3.06Å; D335-R418 VanDerWaalsContact OD1-NH1 3.11Å; D335-R418 IonicContact OD1-NH2 3.44Å; D335-R418 PolarHBondContact OD1-NH2 3.44Å; D335-R418 IonicContact OD2-CZ 3.45Å; D335-R418 IonicContact OD2-NH1 3.75Å; D335-R418 PolarHBondContact OD2-NH1 3.41Å; D335-R418 IonicContact OD2-NH2 2.88Å
336	L	84.9	Confident	76.7	Confident	0 Å²	0	53 Å²	53	0%	0	25%	0.253	C	S	.	.	T	Hydrogen-bonded Turn	trans	-80	-21.2	-177.8	-72.3	173	0	0	0	115.8	I120 F332 V333 R334 I396 V399 W400 R403 Y404	I120-L336 HydrophobicContact CD1-CB 4.39Å; F332-L336 HydrophobicContact CE2-CD1 4.41Å; V333-L336 WeakPolarHBondContact O-CB 3.17Å; V333-L336 PolarHBondContact O-N 3.23Å; V333-L336 VanDerWaalsContact O-N 3.16Å; R334-L336 VanDerWaalsContact C-N 3.25Å; R334-L336 PolarHBondContact O-N 2.94Å; L336-I396 HydrophobicContact CD1-CG2 3.51Å; L336-V399 HydrophobicContact CD2-CG1 4.35Å; L336-W400 HydrophobicContact CD1-CB 4.2Å; L336-W400 HydrophobicContact CD2-CB 3.85Å; L336-W400 HydrophobicContact CD2-CG 4.24Å; L336-R403 PolarHBondContact O-NE 3.37Å; L336-R403 PolarHBondContact O-NH1 2.93Å; L336-R403 PolarHBondContact O-NH2 3.47Å; L336-R403 VanDerWaalsContact O-NH2 3.17Å; L336-Y404 HydrophobicContact CD2-CD2 4.33Å; L336-Y404 HydrophobicContact CD2-CE2 3.73Å
337	T	77.5	Confident	75	Confident	5 Å²	5	52.4 Å²	52.4	3%	0.031	26%	0.255	C	S	.	.			trans	-147.6	138.2	178.9	18	0	0	0	0	110.1	S116 E119 E339 R340 K341	S116-T337 PolarHBondContact O-OG1 3.41Å; E119-T337 HydrophobicContact CB-CG2 4.28Å; T337-E339 PolarHBondContact O-N 3.11Å; T337-R340 PolarHBondContact O-N 2.87Å; T337-K341 PolarHBondContact O-N 3.24Å; T337-K341 VanDerWaalsContact O-N 3.14Å
338	E	74	Confident	73.3	Confident	137 Å²	137	50.7 Å²	50.7	64%	0.64	25%	0.253	S	S	*	.	H	α-helix	trans	-59.4	-36.6	177.2	-67.8	-168.6	171.4	0	0	112.2	R340 K341 K342	E338-R340 PolarHBondContact O-N 2.86Å; E338-K341 WeakPolarHBondContact O-CB 3.27Å; E338-K341 PolarHBondContact O-N 3.08Å; E338-K342 PolarHBondContact O-N 3.05Å; E338-K342 VanDerWaalsContact O-N 3.09Å
339	E	70.1	Confident	71.8	Confident	86 Å²	86	53.3 Å²	53.3	40%	0.402	28%	0.279	S	S	.	.	H	α-helix	trans	-56.8	-40.1	175.2	-70.2	162.4	142.4	0	0	111	G117 F118 T337 I343	G117-E339 WeakPolarHBondContact CA-OE2 3.41Å; F118-E339 PolarHBondContact N-OE2 2.85Å; T337-E339 PolarHBondContact O-N 3.11Å; E339-I343 VanDerWaalsContact O-CD1 3.25Å; E339-I343 WeakPolarHBondContact O-CD1 3.42Å; E339-I343 WeakPolarHBondContact O-CG1 3.43Å
340	R	72.4	Confident	70.5	Confident	3 Å²	3	57.3 Å²	57.3	1%	0.011	30%	0.303	C	S	.	.	H	α-helix	trans	-75.1	-26.4	176.4	-145.7	177.9	-159.9	-91.6	0.7	112.8	S116 V333 T337 E338 I343 Y345 D356 C358	S116-R340 PolarHBondContact OG-NE 3.31Å; S116-R340 VanDerWaalsContact OG-NE 3.14Å; V333-R340 VanDerWaalsContact CG1-CZ 3.48Å; V333-R340 WeakPolarHBondContact O-CD 3.15Å; T337-R340 PolarHBondContact O-N 2.87Å; E338-R340 PolarHBondContact O-N 2.86Å; R340-I343 PolarHBondContact O-N 3.32Å; R340-Y345 HydrophobicContact CG-CE2 4.44Å; R340-D356 IonicContact CZ-OD1 3.11Å; R340-D356 IonicContact NH1-OD1 3.65Å; R340-D356 PolarHBondContact NH1-OD1 2.99Å; R340-D356 IonicContact NH2-OD1 3.81Å; R340-D356 PolarHBondContact NH2-OD1 3.23Å; R340-C358 PolarHBondContact NH2-SG 3.22Å
341	K	70.2	Confident	69.8	Low	116 Å²	116	60 Å²	60	50%	0.504	32%	0.317	S	S	.	.	H	α-helix	trans	-69.6	-34.2	174.3	-67.2	-177.8	-179.5	176.2	0	112.9	R334 T337 E338 I343	R334-K341 HydrophobicContact CG-CG 4.47Å; R334-K341 VanDerWaalsContact O-CG 3.26Å; R334-K341 WeakPolarHBondContact O-CG 3.43Å; T337-K341 PolarHBondContact O-N 3.24Å; T337-K341 VanDerWaalsContact O-N 3.14Å; E338-K341 WeakPolarHBondContact O-CB 3.27Å; E338-K341 PolarHBondContact O-N 3.08Å; K341-I343 PolarHBondContact O-N 3.3Å
342	K	67.1	Low	69.7	Low	171 Å²	171	61.3 Å²	61.3	74%	0.743	32%	0.317	S	S	*	.	S	Bend	trans	-69.3	-18	177.2	-68.9	177.6	-176.7	179.1	0	112.9	E338	E338-K342 PolarHBondContact O-N 3.05Å; E338-K342 VanDerWaalsContact O-N 3.09Å
343	I	64.4	Low	69.6	Low	33 Å²	33	63.5 Å²	63.5	17%	0.169	33%	0.328	C	S	.	.	S	Bend	trans	-103.8	101.9	-170.1	-67.5	176.1	0	0	0	107.6	H165 E339 R340 K341 Y345	H165-I343 WeakPolarHBondContact CE1-CG2 3.33Å; H165-I343 VanDerWaalsContact NE2-CG2 3.27Å; H165-I343 WeakPolarHBondContact NE2-CG2 3.43Å; E339-I343 VanDerWaalsContact O-CD1 3.25Å; E339-I343 WeakPolarHBondContact O-CD1 3.42Å; E339-I343 WeakPolarHBondContact O-CG1 3.43Å; R340-I343 PolarHBondContact O-N 3.32Å; K341-I343 PolarHBondContact O-N 3.3Å; I343-Y345 HydrophobicContact CB-CE2 4.15Å; I343-Y345 HydrophobicContact CG2-CD1 4.33Å; I343-Y345 HydrophobicContact CG2-CD2 3.77Å; I343-Y345 HydrophobicContact CG2-CE1 3.76Å; I343-Y345 HydrophobicContact CG2-CE2 3.17Å; I343-Y345 HydrophobicContact CG2-CG 4.33Å; I343-Y345 WeakPolarHBondContact CG2-OH 3.35Å; I343-Y345 PolarHBondContact O-N 3.38Å; I343-Y345 VanDerWaalsContact O-N 3.09Å
344	D	61.6	Low	69.6	Low	87 Å²	87	67.5 Å²	67.5	47%	0.465	35%	0.346	S	S	.	.			trans	-77.4	96.6	-179.5	-168	25.9	0	0	0	111.1	H165	H165-D344 PolarHBondContact ND1-O 2.84Å; H165-D344 VanDerWaalsContact ND1-O 3.08Å
345	Y	65.5	Low	69.7	Low	19 Å²	19	67.7 Å²	67.7	8%	0.075	35%	0.346	C	S	.	.			trans	-88.9	116	167.6	-63.8	-64.3	0	0	0	108.6	C164 R340 I343 N347 P357	C164-Y345 HydrophobicContact CB-CD1 3.8Å; C164-Y345 HydrophobicContact CB-CE1 3.48Å; C164-Y345 VanDerWaalsContact CB-CE1 3.48Å; R340-Y345 HydrophobicContact CG-CE2 4.44Å; I343-Y345 HydrophobicContact CB-CE2 4.15Å; I343-Y345 HydrophobicContact CG2-CD1 4.33Å; I343-Y345 HydrophobicContact CG2-CD2 3.77Å; I343-Y345 HydrophobicContact CG2-CE1 3.76Å; I343-Y345 HydrophobicContact CG2-CE2 3.17Å; I343-Y345 HydrophobicContact CG2-CG 4.33Å; I343-Y345 WeakPolarHBondContact CG2-OH 3.35Å; I343-Y345 PolarHBondContact O-N 3.38Å; I343-Y345 VanDerWaalsContact O-N 3.09Å; Y345-N347 PolarHBondContact O-N 2.65Å; Y345-P357 HydrophobicContact CE1-CG 3.81Å; Y345-P357 HydrophobicContact CE2-CG 4.13Å; Y345-P357 WeakPolarHBondContact OH-CG 3.42Å
346	S	57.8	Low	70.1	Confident	10 Å²	10	66.8 Å²	66.8	7%	0.07	34%	0.341	C	S	.	.			trans	-28.5	124.1	-178.4	-170	0	0	0	0	115.6	N348 R355	S346-N348 PolarHBondContact O-N 3.49Å; S346-N348 PolarHBondContact OG-N 3.01Å; S346-R355 PolarHBondContact OG-NH1 3.16Å
347	N	56.8	Low	70.4	Confident	110 Å²	110	66.8 Å²	66.8	59%	0.588	34%	0.341	S	S	*	.			trans	-73.7	-2.6	170	-76.5	-23.7	0	0	0	113.9	Y345 S349	Y345-N347 PolarHBondContact O-N 2.65Å; N347-S349 PolarHBondContact O-N 3.36Å
348	N	53.7	Low	71.1	Confident	104 Å²	104	66.6 Å²	66.6	56%	0.556	34%	0.34	S	S	*	.			trans	-69.1	120.2	-174.3	-78.5	3.1	0	0	0	111.4	S346 S350 Q352	S346-N348 PolarHBondContact O-N 3.49Å; S346-N348 PolarHBondContact OG-N 3.01Å; N348-S350 PolarHBondContact O-N 3.01Å; N348-Q352 PolarHBondContact O-N 2.93Å
349	S	56.1	Low	72	Confident	107 Å²	107	60 Å²	60	75%	0.748	31%	0.31	S	S	*	.	G	3₁₀ helix	trans	-60.8	-39.5	-168.5	58	0	0	0	0	114.7	N347 N351	N347-S349 PolarHBondContact O-N 3.36Å; S349-N351 VanDerWaalsContact C-N 3.34Å; S349-N351 PolarHBondContact O-N 3.29Å
350	S	56.8	Low	73.1	Confident	102 Å²	102	56.3 Å²	56.3	71%	0.713	29%	0.292	S	S	*	.	G	3₁₀ helix	trans	-72	-22.5	-170.1	57.9	0	0	0	0	114.9	N348	N348-S350 PolarHBondContact O-N 3.01Å
351	N	67.9	Low	74.2	Confident	68 Å²	68	56.3 Å²	56.3	36%	0.364	29%	0.293	S	S	.	.	G	3₁₀ helix	trans	-128	21.7	-177.2	-77.3	-42.9	0	0	0	113	S349 M353 F354 R355	S349-N351 VanDerWaalsContact C-N 3.34Å; S349-N351 PolarHBondContact O-N 3.29Å; N351-M353 PolarHBondContact O-N 3.38Å; N351-F354 PolarHBondContact O-N 2.9Å; N351-R355 WeakPolarHBondContact O-CG 3.3Å; N351-R355 PolarHBondContact O-N 3Å
352	Q	78	Confident	75.5	Confident	52 Å²	52	50.8 Å²	50.8	24%	0.243	27%	0.269	C	S	.	.	H	α-helix	trans	-62.8	-42.7	-169.7	-153	-178.4	14.8	0	0	112.5	P330 N348 F354 R355 D356	P330-Q352 VanDerWaalsContact CD-CD 3.49Å; P330-Q352 HydrophobicContact CG-CG 3.71Å; N348-Q352 PolarHBondContact O-N 2.93Å; Q352-F354 PolarHBondContact O-N 2.93Å; Q352-R355 PolarHBondContact O-N 3Å; Q352-D356 WeakPolarHBondContact O-CB 3.46Å; Q352-D356 PolarHBondContact O-N 3.38Å
353	M	83.9	Confident	76.8	Confident	55 Å²	55	44.9 Å²	44.9	27%	0.271	25%	0.245	S	C	.	.	H	α-helix	trans	-65.1	-38.5	179.9	-67.9	-174.3	67.8	0	0	113.1	Y325 F326 N351 R355 G359 L360 I362 I363	Y325-M353 HydrophobicContact CE1-CE 4.35Å; Y325-M353 HydrophobicContact CE1-CG 4.19Å; F326-M353 HydrophobicContact CE1-CE 4.02Å; F326-M353 HydrophobicContact CE1-SD 3.99Å; F326-M353 HydrophobicContact CZ-CE 3.86Å; F326-M353 HydrophobicContact CZ-SD 4.44Å; N351-M353 PolarHBondContact O-N 3.38Å; M353-R355 PolarHBondContact O-N 3.11Å; M353-G359 CarbonylContact O-C 3.54Å; M353-G359 VanDerWaalsContact O-CA 3.3Å; M353-G359 WeakPolarHBondContact O-CA 3.32Å; M353-L360 PolarHBondContact O-N 3.4Å; M353-L360 VanDerWaalsContact O-N 3.1Å; M353-I362 HydrophobicContact CE-CG2 4.25Å; M353-I363 HydrophobicContact CB-CD1 4.03Å; M353-I363 HydrophobicContact CE-CD1 4.46Å; M353-I363 HydrophobicContact CE-CG1 4.18Å
354	F	84.2	Confident	78.4	Confident	84 Å²	84	43.8 Å²	43.8	37%	0.368	24%	0.239	S	C	.	.	H	α-helix	trans	-73.9	-16.5	179.2	-71.2	-81.3	0	0	0	113.2	W209 N351 Q352 I363	W209-F354 HydrophobicContact CH2-CB 3.91Å; W209-F354 HydrophobicContact CH2-CD1 4.22Å; W209-F354 HydrophobicContact CH2-CG 4.23Å; W209-F354 HydrophobicContact CZ2-CB 3.63Å; W209-F354 HydrophobicContact CZ2-CD1 4.29Å; W209-F354 HydrophobicContact CZ2-CG 4.31Å; W209-F354 HydrophobicContact CZ3-CD1 4.48Å; N351-F354 PolarHBondContact O-N 2.9Å; Q352-F354 PolarHBondContact O-N 2.93Å; F354-I363 HydrophobicContact CD1-CD1 3.84Å; F354-I363 HydrophobicContact CD2-CD1 4.38Å; F354-I363 HydrophobicContact CE1-CD1 3.75Å; F354-I363 HydrophobicContact CE2-CD1 4.3Å; F354-I363 HydrophobicContact CG-CD1 4.15Å; F354-I363 HydrophobicContact CZ-CD1 3.99Å
355	R	82.9	Confident	80	Confident	51 Å²	51	39.9 Å²	39.9	19%	0.192	22%	0.218	C	C	.	.	H	α-helix	trans	-104.4	-15.1	-179.2	-68.6	-179.7	178.6	-176.7	-1.4	113.4	C164 S346 N351 Q352 M353	C164-R355 CarbonylContact C-O 3.48Å; C164-R355 WeakPolarHBondContact CA-O 3.42Å; C164-R355 WeakPolarHBondContact CB-O 3.49Å; S346-R355 PolarHBondContact OG-NH1 3.16Å; N351-R355 WeakPolarHBondContact O-CG 3.3Å; N351-R355 PolarHBondContact O-N 3Å; Q352-R355 PolarHBondContact O-N 3Å; M353-R355 PolarHBondContact O-N 3.11Å
356	D	87.6	Confident	81.5	Confident	3 Å²	3	42.5 Å²	42.5	2%	0.016	23%	0.233	C	C	.	.	S	Bend	trans	-96.1	132.5	174	169	74.4	0	0	0	109.8	Y325 P330 R340 Q352 C358 G359 L360	Y325-D356 VanDerWaalsContact CE2-OD2 3.25Å; Y325-D356 WeakPolarHBondContact CE2-OD2 3.49Å; Y325-D356 PolarHBondContact OH-OD2 3.19Å; P330-D356 HydrophobicContact CB-CB 3.95Å; P330-D356 VanDerWaalsContact CB-CG 3.48Å; P330-D356 HydrophobicContact CG-CB 4.38Å; R340-D356 IonicContact CZ-OD1 3.11Å; R340-D356 IonicContact NH1-OD1 3.65Å; R340-D356 PolarHBondContact NH1-OD1 2.99Å; R340-D356 IonicContact NH2-OD1 3.81Å; R340-D356 PolarHBondContact NH2-OD1 3.23Å; Q352-D356 WeakPolarHBondContact O-CB 3.46Å; Q352-D356 PolarHBondContact O-N 3.38Å; D356-C358 VanDerWaalsContact C-N 3.27Å; D356-C358 PolarHBondContact O-N 3.32Å; D356-C358 WeakPolarHBondContact OD2-CA 3.26Å; D356-C358 VanDerWaalsContact OD2-CB 3.24Å; D356-C358 WeakPolarHBondContact OD2-CB 3.29Å; D356-C358 PolarHBondContact OD2-N 3.37Å; D356-C358 VanDerWaalsContact OD2-N 3.12Å; D356-G359 PolarHBondContact O-N 3.15Å; D356-G359 VanDerWaalsContact O-N 3.11Å; D356-G359 PolarHBondContact OD2-N 3.38Å; D356-L360 PolarHBondContact O-N 3.13Å
357	P	90.3	Very high	83.4	Confident	0 Å²	0	47.4 Å²	47.4	0%	0	25%	0.25	C	S	.	.	H	α-helix	trans	-56.6	-38.1	-179.6	-26.2	32.4	0	0	0	113.8	L115 W160 C164 Y345 L360 C361	L115-P357 HydrophobicContact CD1-CB 4.28Å; L115-P357 HydrophobicContact CD2-CB 3.8Å; L115-P357 HydrophobicContact CD2-CG 4.02Å; L115-P357 HydrophobicContact CG-CB 4.47Å; W160-P357 HydrophobicContact CE3-CB 4.17Å; W160-P357 HydrophobicContact CZ3-CB 4.37Å; C164-P357 HydrophobicContact CB-CG 4.2Å; Y345-P357 HydrophobicContact CE1-CG 3.81Å; Y345-P357 HydrophobicContact CE2-CG 4.13Å; Y345-P357 WeakPolarHBondContact OH-CG 3.42Å; P357-L360 PolarHBondContact O-N 3.31Å; P357-C361 PolarHBondContact O-N 3.16Å; P357-C361 PolarHBondContact O-SG 3.24Å
358	C	92.6	Very high	85.3	Confident	0 Å²	0	42.3 Å²	42.3	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-68.3	-41.8	178	-60.6	0	0	0	0	111.3	F321 Y325 R340 D356 L360 C361 I362 Y392	F321-C358 HydrophobicContact CE1-CB 4.4Å; F321-C358 HydrophobicContact CZ-CB 3.76Å; Y325-C358 HydrophobicContact CD2-CB 4.3Å; Y325-C358 HydrophobicContact CE2-CB 3.83Å; R340-C358 PolarHBondContact NH2-SG 3.22Å; D356-C358 VanDerWaalsContact C-N 3.27Å; D356-C358 PolarHBondContact O-N 3.32Å; D356-C358 WeakPolarHBondContact OD2-CA 3.26Å; D356-C358 VanDerWaalsContact OD2-CB 3.24Å; D356-C358 WeakPolarHBondContact OD2-CB 3.29Å; D356-C358 PolarHBondContact OD2-N 3.37Å; D356-C358 VanDerWaalsContact OD2-N 3.12Å; C358-L360 VanDerWaalsContact C-N 3.34Å; C358-L360 PolarHBondContact O-N 3.43Å; C358-C361 WeakPolarHBondContact O-CB 3.24Å; C358-C361 PolarHBondContact O-N 3.23Å; C358-I362 WeakPolarHBondContact O-CG1 3.45Å; C358-I362 PolarHBondContact O-N 2.85Å; C358-Y392 PolarHBondContact SG-OH 3Å
359	G	92.7	Very high	87.3	Confident	0 Å²	0	38.1 Å²	38.1	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-58.3	-45	174.5	0	0	0	0	0	112.2	Y325 M353 D356 C361 I362 I363	Y325-G359 WeakPolarHBondContact OH-CA 3.49Å; Y325-G359 PolarHBondContact OH-N 2.8Å; M353-G359 CarbonylContact O-C 3.54Å; M353-G359 VanDerWaalsContact O-CA 3.3Å; M353-G359 WeakPolarHBondContact O-CA 3.32Å; D356-G359 PolarHBondContact O-N 3.15Å; D356-G359 VanDerWaalsContact O-N 3.11Å; D356-G359 PolarHBondContact OD2-N 3.38Å; G359-C361 PolarHBondContact O-N 3.33Å; G359-I362 WeakPolarHBondContact O-CB 3.49Å; G359-I362 PolarHBondContact O-N 3.13Å; G359-I363 VanDerWaalsContact O-CG1 3.32Å; G359-I363 WeakPolarHBondContact O-CG1 3.4Å; G359-I363 PolarHBondContact O-N 3.41Å
360	L	93.4	Very high	89.2	Confident	7 Å²	7	36.8 Å²	36.8	4%	0.037	18%	0.184	C	C	.	.	H	α-helix	trans	-64	-41.7	176	-171.5	62.2	0	0	0	111.7	Y158 W160 I163 L206 M353 D356 P357 C358 I362 I363 V364	Y158-L360 HydrophobicContact CE1-CD2 4.1Å; W160-L360 HydrophobicContact CE3-CD2 4.29Å; W160-L360 HydrophobicContact CH2-CD2 4.47Å; W160-L360 HydrophobicContact CZ3-CB 4.28Å; W160-L360 HydrophobicContact CZ3-CD2 3.77Å; W160-L360 HydrophobicContact CZ3-CG 4.3Å; I163-L360 HydrophobicContact CG2-CD2 4.3Å; L206-L360 HydrophobicContact CD2-CD2 4.36Å; M353-L360 PolarHBondContact O-N 3.4Å; M353-L360 VanDerWaalsContact O-N 3.1Å; D356-L360 PolarHBondContact O-N 3.13Å; P357-L360 PolarHBondContact O-N 3.31Å; C358-L360 VanDerWaalsContact C-N 3.34Å; C358-L360 PolarHBondContact O-N 3.43Å; L360-I362 VanDerWaalsContact C-N 3.34Å; L360-I362 PolarHBondContact O-N 3.04Å; L360-I363 PolarHBondContact O-N 2.9Å; L360-V364 HydrophobicContact CG-CG2 4.5Å; L360-V364 VanDerWaalsContact O-CG2 3.25Å; L360-V364 WeakPolarHBondContact O-CG2 3.45Å; L360-V364 PolarHBondContact O-N 3.01Å
361	C	95.8	Very high	91	Very high	3 Å²	3	33.4 Å²	33.4	2%	0.02	16%	0.16	C	C	.	.	H	α-helix	trans	-60.7	-40.1	173.6	-70.7	0	0	0	0	112.5	P357 C358 G359 M365 L389 F393	P357-C361 PolarHBondContact O-N 3.16Å; P357-C361 PolarHBondContact O-SG 3.24Å; C358-C361 WeakPolarHBondContact O-CB 3.24Å; C358-C361 PolarHBondContact O-N 3.23Å; G359-C361 PolarHBondContact O-N 3.33Å; C361-M365 VanDerWaalsContact O-CB 3.25Å; C361-M365 WeakPolarHBondContact O-CB 3.19Å; C361-M365 PolarHBondContact O-N 2.8Å; C361-L389 HydrophobicContact CB-CD2 4.36Å; C361-F393 HydrophobicContact CB-CE1 3.91Å; C361-F393 HydrophobicContact CB-CZ 3.73Å
362	I	95.9	Very high	92.2	Very high	1 Å²	1	30.5 Å²	30.5	1%	0.005	14%	0.144	C	C	.	.	H	α-helix	trans	-61.9	-48.8	175.1	-70.1	166.2	0	0	0	109.8	F321 Y325 M353 C358 G359 L360 V364 M365 I366 F393	F321-I362 HydrophobicContact CE1-CD1 3.96Å; F321-I362 HydrophobicContact CE1-CG1 4.31Å; Y325-I362 HydrophobicContact CD1-CD1 3.47Å; Y325-I362 VanDerWaalsContact CD1-CD1 3.47Å; Y325-I362 HydrophobicContact CD2-CD1 4.34Å; Y325-I362 HydrophobicContact CE1-CD1 3.81Å; Y325-I362 HydrophobicContact CG-CD1 3.77Å; M353-I362 HydrophobicContact CE-CG2 4.25Å; C358-I362 WeakPolarHBondContact O-CG1 3.45Å; C358-I362 PolarHBondContact O-N 2.85Å; G359-I362 WeakPolarHBondContact O-CB 3.49Å; G359-I362 PolarHBondContact O-N 3.13Å; L360-I362 VanDerWaalsContact C-N 3.34Å; L360-I362 PolarHBondContact O-N 3.04Å; I362-V364 PolarHBondContact O-N 3.37Å; I362-M365 PolarHBondContact O-N 3.11Å; I362-I366 HydrophobicContact CG2-CD1 3.57Å; I362-I366 HydrophobicContact CG2-CG1 4.28Å; I362-I366 WeakPolarHBondContact O-CB 3.21Å; I362-I366 VanDerWaalsContact O-CG1 3.3Å; I362-I366 WeakPolarHBondContact O-CG1 3.37Å; I362-I366 PolarHBondContact O-N 3.24Å; I362-F393 HydrophobicContact CB-CZ 4.47Å; I362-F393 HydrophobicContact CG1-CE1 4.21Å; I362-F393 HydrophobicContact CG1-CE2 4.06Å; I362-F393 HydrophobicContact CG1-CZ 3.59Å
363	I	95.7	Very high	93	Very high	46 Å²	46	28.6 Å²	28.6	24%	0.236	14%	0.136	C	C	.	.	H	α-helix	trans	-59.8	-47.2	-179.4	-68.8	164	0	0	0	110.5	M353 F354 G359 L360 I366 W367	M353-I363 HydrophobicContact CB-CD1 4.03Å; M353-I363 HydrophobicContact CE-CD1 4.46Å; M353-I363 HydrophobicContact CE-CG1 4.18Å; F354-I363 HydrophobicContact CD1-CD1 3.84Å; F354-I363 HydrophobicContact CD2-CD1 4.38Å; F354-I363 HydrophobicContact CE1-CD1 3.75Å; F354-I363 HydrophobicContact CE2-CD1 4.3Å; F354-I363 HydrophobicContact CG-CD1 4.15Å; F354-I363 HydrophobicContact CZ-CD1 3.99Å; G359-I363 VanDerWaalsContact O-CG1 3.32Å; G359-I363 WeakPolarHBondContact O-CG1 3.4Å; G359-I363 PolarHBondContact O-N 3.41Å; L360-I363 PolarHBondContact O-N 2.9Å; I363-I366 PolarHBondContact O-N 3.14Å; I363-W367 VanDerWaalsContact O-CB 3.22Å; I363-W367 WeakPolarHBondContact O-CB 3.18Å; I363-W367 PolarHBondContact O-N 3.38Å
364	V	96.5	Very high	93.3	Very high	10 Å²	10	33.7 Å²	33.7	6%	0.061	16%	0.157	C	C	.	.	H	α-helix	trans	-62.8	-44	178.6	173	0	0	0	0	111.2	I202 L206 L360 I362 W367 I368 L389	I202-V364 HydrophobicContact CD1-CG1 4.05Å; I202-V364 HydrophobicContact CG1-CG1 3.82Å; L206-V364 HydrophobicContact CD2-CG2 3.78Å; L206-V364 HydrophobicContact CG-CG2 4.3Å; L360-V364 HydrophobicContact CG-CG2 4.5Å; L360-V364 VanDerWaalsContact O-CG2 3.25Å; L360-V364 WeakPolarHBondContact O-CG2 3.45Å; L360-V364 PolarHBondContact O-N 3.01Å; I362-V364 PolarHBondContact O-N 3.37Å; V364-W367 PolarHBondContact O-N 3.16Å; V364-I368 HydrophobicContact CG1-CD1 3.89Å; V364-I368 VanDerWaalsContact O-CG1 3.26Å; V364-I368 WeakPolarHBondContact O-CG1 3.38Å; V364-I368 PolarHBondContact O-N 2.74Å; V364-L389 HydrophobicContact CB-CD1 4.11Å; V364-L389 HydrophobicContact CG1-CD1 3.74Å
365	M	96.4	Very high	93.5	Very high	5 Å²	5	32.7 Å²	32.7	3%	0.025	16%	0.156	C	C	.	.	H	α-helix	trans	-62.7	-46.2	178.3	-176.3	178.8	73.2	0	0	111.7	F307 I322 C361 I362 I368 I369 L389 A390 F393	F307-M365 HydrophobicContact CE1-CE 4.5Å; F307-M365 HydrophobicContact CE1-CG 4.42Å; F307-M365 HydrophobicContact CE1-SD 3.79Å; F307-M365 HydrophobicContact CZ-CG 4.18Å; F307-M365 HydrophobicContact CZ-SD 3.68Å; I322-M365 HydrophobicContact CD1-CE 4.1Å; C361-M365 VanDerWaalsContact O-CB 3.25Å; C361-M365 WeakPolarHBondContact O-CB 3.19Å; C361-M365 PolarHBondContact O-N 2.8Å; I362-M365 PolarHBondContact O-N 3.11Å; M365-I368 PolarHBondContact O-N 2.88Å; M365-I369 HydrophobicContact CG-CD1 4.18Å; M365-I369 WeakPolarHBondContact O-CG1 3.5Å; M365-I369 PolarHBondContact O-N 3.28Å; M365-I369 VanDerWaalsContact O-N 3.07Å; M365-L389 HydrophobicContact CB-CD1 4.24Å; M365-A390 HydrophobicContact SD-CB 4.11Å; M365-F393 HydrophobicContact CE-CD2 4.32Å; M365-F393 HydrophobicContact CE-CE2 3.68Å; M365-F393 HydrophobicContact SD-CD2 4.45Å; M365-F393 HydrophobicContact SD-CE2 3.87Å
366	I	96.1	Very high	93.6	Very high	75 Å²	75	31.8 Å²	31.8	39%	0.385	16%	0.156	S	C	.	.	H	α-helix	trans	-62.1	-45.4	176.3	-70.8	172.9	0	0	0	110.4	I362 I363 I368 I369 I370	I362-I366 HydrophobicContact CG2-CD1 3.57Å; I362-I366 HydrophobicContact CG2-CG1 4.28Å; I362-I366 WeakPolarHBondContact O-CB 3.21Å; I362-I366 VanDerWaalsContact O-CG1 3.3Å; I362-I366 WeakPolarHBondContact O-CG1 3.37Å; I362-I366 PolarHBondContact O-N 3.24Å; I363-I366 PolarHBondContact O-N 3.14Å; I366-I368 PolarHBondContact O-N 3.31Å; I366-I369 PolarHBondContact O-N 3.05Å; I366-I370 HydrophobicContact CG2-CD1 3.5Å; I366-I370 HydrophobicContact CG2-CG1 4.13Å; I366-I370 WeakPolarHBondContact O-CB 3.41Å; I366-I370 VanDerWaalsContact O-CG1 3.3Å; I366-I370 WeakPolarHBondContact O-CG1 3.41Å; I366-I370 PolarHBondContact O-N 2.88Å
367	W	97.3	Very high	93.5	Very high	112 Å²	112	33 Å²	33	42%	0.424	16%	0.161	S	C	.	.	H	α-helix	trans	-57.2	-48.2	178	173.5	-105.5	0	0	0	112	I201 I363 V364 I369 I370 C371	I201-W367 VanDerWaalsContact O-CD1 3.24Å; I201-W367 PolarHBondContact O-NE1 3.09Å; I363-W367 VanDerWaalsContact O-CB 3.22Å; I363-W367 WeakPolarHBondContact O-CB 3.18Å; I363-W367 PolarHBondContact O-N 3.38Å; V364-W367 PolarHBondContact O-N 3.16Å; W367-I369 PolarHBondContact O-N 3.32Å; W367-I370 PolarHBondContact O-N 2.77Å; W367-C371 WeakPolarHBondContact CZ2-SG 3.37Å; W367-C371 WeakPolarHBondContact O-CB 3.09Å; W367-C371 PolarHBondContact O-N 3.16Å; W367-C371 PolarHBondContact O-SG 3.02Å; W367-C371 VanDerWaalsContact O-SG 3.33Å
368	I	96.8	Very high	93.6	Very high	4 Å²	4	33.6 Å²	33.6	2%	0.021	16%	0.164	C	C	.	.	H	α-helix	trans	-56.3	-51.8	175.5	-69.5	164.9	0	0	0	110	I201 I202 V364 M365 I366 I370 C371 Y372 I383	I201-I368 HydrophobicContact CG2-CG1 4.38Å; I202-I368 HydrophobicContact CB-CD1 4.31Å; I202-I368 HydrophobicContact CD1-CD1 4.09Å; I202-I368 HydrophobicContact CG1-CD1 4.25Å; V364-I368 HydrophobicContact CG1-CD1 3.89Å; V364-I368 VanDerWaalsContact O-CG1 3.26Å; V364-I368 WeakPolarHBondContact O-CG1 3.38Å; V364-I368 PolarHBondContact O-N 2.74Å; M365-I368 PolarHBondContact O-N 2.88Å; I366-I368 PolarHBondContact O-N 3.31Å; I368-I370 VanDerWaalsContact C-N 3.33Å; I368-I370 PolarHBondContact O-N 3.35Å; I368-C371 PolarHBondContact O-N 3.48Å; I368-Y372 HydrophobicContact CG2-CD2 3.81Å; I368-Y372 HydrophobicContact CG2-CE2 3.97Å; I368-Y372 VanDerWaalsContact O-CD2 3.26Å; I368-Y372 WeakPolarHBondContact O-CD2 3.39Å; I368-Y372 PolarHBondContact O-N 2.79Å; I368-Y372 VanDerWaalsContact O-N 3.1Å; I368-I383 HydrophobicContact CG2-CB 4.32Å; I368-I383 HydrophobicContact CG2-CG2 4.15Å
369	I	96.3	Very high	93.6	Very high	16 Å²	16	35.1 Å²	35.1	8%	0.082	17%	0.171	C	C	.	.	H	α-helix	trans	-59.9	-44.5	-178.4	-68.8	168.6	0	0	0	110.7	F307 M365 I366 W367 S373	F307-I369 HydrophobicContact CD1-CD1 3.89Å; F307-I369 HydrophobicContact CE1-CD1 4.06Å; F307-I369 HydrophobicContact CG-CD1 4.2Å; M365-I369 HydrophobicContact CG-CD1 4.18Å; M365-I369 WeakPolarHBondContact O-CG1 3.5Å; M365-I369 PolarHBondContact O-N 3.28Å; M365-I369 VanDerWaalsContact O-N 3.07Å; I366-I369 PolarHBondContact O-N 3.05Å; W367-I369 PolarHBondContact O-N 3.32Å; I369-S373 WeakPolarHBondContact O-CB 3.25Å; I369-S373 PolarHBondContact O-N 3.3Å; I369-S373 PolarHBondContact O-OG 3.33Å
370	I	96	Very high	93.8	Very high	78 Å²	78	38.1 Å²	38.1	40%	0.4	18%	0.184	S	C	.	.	H	α-helix	trans	-63.6	-50.5	179.5	-70.9	175.1	0	0	0	111	I366 W367 I368 Y372 S373 F374	I366-I370 HydrophobicContact CG2-CD1 3.5Å; I366-I370 HydrophobicContact CG2-CG1 4.13Å; I366-I370 WeakPolarHBondContact O-CB 3.41Å; I366-I370 VanDerWaalsContact O-CG1 3.3Å; I366-I370 WeakPolarHBondContact O-CG1 3.41Å; I366-I370 PolarHBondContact O-N 2.88Å; W367-I370 PolarHBondContact O-N 2.77Å; I368-I370 VanDerWaalsContact C-N 3.33Å; I368-I370 PolarHBondContact O-N 3.35Å; I370-Y372 VanDerWaalsContact C-N 3.34Å; I370-Y372 PolarHBondContact O-N 3.32Å; I370-S373 WeakPolarHBondContact O-CB 3.32Å; I370-S373 PolarHBondContact O-N 3.34Å; I370-S373 VanDerWaalsContact O-N 3.08Å; I370-F374 HydrophobicContact CG2-CD2 4.05Å; I370-F374 HydrophobicContact CG2-CE2 3.6Å; I370-F374 VanDerWaalsContact O-CD2 3.23Å; I370-F374 WeakPolarHBondContact O-CD2 3.39Å; I370-F374 PolarHBondContact O-N 3.42Å
371	C	94.7	Very high	93.8	Very high	31 Å²	31	38.2 Å²	38.2	21%	0.209	18%	0.184	C	C	.	.	H	α-helix	trans	-57.5	-46	-178.8	-72.5	0	0	0	0	112.1	I201 W367 I368	I201-C371 HydrophobicContact CD1-CB 4.1Å; I201-C371 HydrophobicContact CG1-CB 4.37Å; I201-C371 HydrophobicContact CG2-CB 3.75Å; W367-C371 WeakPolarHBondContact CZ2-SG 3.37Å; W367-C371 WeakPolarHBondContact O-CB 3.09Å; W367-C371 PolarHBondContact O-N 3.16Å; W367-C371 PolarHBondContact O-SG 3.02Å; W367-C371 VanDerWaalsContact O-SG 3.33Å; I368-C371 PolarHBondContact O-N 3.48Å
372	Y	93.5	Very high	93.8	Very high	8 Å²	8	39.2 Å²	39.2	3%	0.031	19%	0.188	C	C	.	.	H	α-helix	trans	-74.3	-25.1	177.7	-75	-73.1	0	0	0	113	T198 I201 Y302 I368 I370 F374 L375 F382 I383	T198-Y372 VanDerWaalsContact CB-OH 3.31Å; T198-Y372 WeakPolarHBondContact CB-OH 3.45Å; I201-Y372 HydrophobicContact CD1-CD1 4.49Å; I201-Y372 HydrophobicContact CD1-CD2 4.24Å; I201-Y372 HydrophobicContact CD1-CE1 4Å; I201-Y372 HydrophobicContact CD1-CE2 3.77Å; Y302-Y372 WeakPolarHBondContact CE2-O 3.26Å; I368-Y372 HydrophobicContact CG2-CD2 3.81Å; I368-Y372 HydrophobicContact CG2-CE2 3.97Å; I368-Y372 VanDerWaalsContact O-CD2 3.26Å; I368-Y372 WeakPolarHBondContact O-CD2 3.39Å; I368-Y372 PolarHBondContact O-N 2.79Å; I368-Y372 VanDerWaalsContact O-N 3.1Å; I370-Y372 VanDerWaalsContact C-N 3.34Å; I370-Y372 PolarHBondContact O-N 3.32Å; Y372-F374 VanDerWaalsContact C-N 3.28Å; Y372-F374 PolarHBondContact O-N 3.44Å; Y372-L375 HydrophobicContact CD1-CD1 3.81Å; Y372-L375 HydrophobicContact CE1-CD1 4.34Å; Y372-L375 WeakPolarHBondContact O-CB 3.46Å; Y372-L375 PolarHBondContact O-N 3.34Å; Y372-L375 VanDerWaalsContact O-N 3.16Å; Y372-F382 HydrophobicContact CD1-CB 3.78Å; Y372-F382 HydrophobicContact CD1-CD2 4.46Å; Y372-F382 HydrophobicContact CD1-CG 4.44Å; Y372-F382 HydrophobicContact CE1-CB 3.65Å; Y372-F382 HydrophobicContact CE1-CG 4.27Å; Y372-F382 VanDerWaalsContact CE2-O 3.32Å; Y372-F382 WeakPolarHBondContact CE2-O 3.41Å; Y372-F382 HydrophobicContact CG-CB 4.39Å; Y372-F382 PolarHBondContact OH-O 3.19Å; Y372-I383 HydrophobicContact CD2-CG2 3.74Å; Y372-I383 HydrophobicContact CG-CG2 3.98Å
373	S	94.3	Very high	93.9	Very high	11 Å²	11	39.1 Å²	39.1	8%	0.077	19%	0.188	C	C	.	.	H	α-helix	trans	-64.6	-31.5	177.4	-70.5	0	0	0	0	113.2	W299 I369 I370 L375 K378	W299-S373 WeakPolarHBondContact CA-O 2.81Å; W299-S373 WeakPolarHBondContact O-CB 3.38Å; W299-S373 PolarHBondContact O-OG 2.96Å; I369-S373 WeakPolarHBondContact O-CB 3.25Å; I369-S373 PolarHBondContact O-N 3.3Å; I369-S373 PolarHBondContact O-OG 3.33Å; I370-S373 WeakPolarHBondContact O-CB 3.32Å; I370-S373 PolarHBondContact O-N 3.34Å; I370-S373 VanDerWaalsContact O-N 3.08Å; S373-L375 VanDerWaalsContact C-N 3.28Å; S373-L375 PolarHBondContact O-N 3.17Å; S373-K378 WeakPolarHBondContact O-CE 3.11Å; S373-K378 PolarHBondContact O-NZ 2.95Å; S373-K378 VanDerWaalsContact O-NZ 3.11Å
374	F	90.5	Very high	93.9	Very high	163 Å²	163	37 Å²	37	72%	0.715	18%	0.177	S	C	*	.	T	Hydrogen-bonded Turn	trans	-75.6	-12.8	175.8	-74.1	-67.1	0	0	0	114.1	I370 Y372	I370-F374 HydrophobicContact CG2-CD2 4.05Å; I370-F374 HydrophobicContact CG2-CE2 3.6Å; I370-F374 VanDerWaalsContact O-CD2 3.23Å; I370-F374 WeakPolarHBondContact O-CD2 3.39Å; I370-F374 PolarHBondContact O-N 3.42Å; Y372-F374 VanDerWaalsContact C-N 3.28Å; Y372-F374 PolarHBondContact O-N 3.44Å
375	L	87.7	Confident	94	Very high	63 Å²	63	36.8 Å²	36.8	33%	0.33	18%	0.176	S	C	.	.	S	Bend	trans	-78.4	132.1	174	-66.2	172.2	0	0	0	110	Y372 S373 H377 K378	Y372-L375 HydrophobicContact CD1-CD1 3.81Å; Y372-L375 HydrophobicContact CE1-CD1 4.34Å; Y372-L375 WeakPolarHBondContact O-CB 3.46Å; Y372-L375 PolarHBondContact O-N 3.34Å; Y372-L375 VanDerWaalsContact O-N 3.16Å; S373-L375 VanDerWaalsContact C-N 3.28Å; S373-L375 PolarHBondContact O-N 3.17Å; L375-H377 VanDerWaalsContact C-N 3.34Å; L375-H377 PolarHBondContact O-N 3.45Å; L375-K378 WeakPolarHBondContact O-CE 3.31Å; L375-K378 PolarHBondContact O-NZ 3Å
376	P	84.8	Confident	94	Very high	32 Å²	32	36.6 Å²	36.6	21%	0.208	18%	0.175	C	C	.	.	S	Bend	trans	-59	-46.8	178.4	-25.4	34.2	0	0	0	112	R292 V296 Q297	R292-P376 HydrophobicContact CG-CB 4.06Å; R292-P376 HydrophobicContact CG-CG 4Å; V296-P376 WeakPolarHBondContact CA-O 3.36Å; V296-P376 HydrophobicContact CG1-CB 3.96Å; V296-P376 HydrophobicContact CG2-CB 3.99Å; Q297-P376 PolarHBondContact N-O 3.39Å; Q297-P376 VanDerWaalsContact N-O 3.07Å
377	H	87.2	Confident	94.1	Very high	27 Å²	27	33 Å²	33	13%	0.125	16%	0.157	C	C	.	.	S	Bend	trans	-85.3	131.1	177.5	-176.8	61.3	0	0	0	111.5	S291 A295 L375 E379 F382	S291-H377 VanDerWaalsContact O-CB 3.25Å; S291-H377 WeakPolarHBondContact O-CB 3.42Å; A295-H377 VanDerWaalsContact O-CA 3.3Å; A295-H377 WeakPolarHBondContact O-CA 3.37Å; A295-H377 PolarHBondContact O-ND1 2.89Å; A295-H377 VanDerWaalsContact O-ND1 3.11Å; L375-H377 VanDerWaalsContact C-N 3.34Å; L375-H377 PolarHBondContact O-N 3.45Å; H377-E379 IonicContact CE1-OE1 3.55Å; H377-E379 IonicContact NE2-OE1 3.61Å; H377-E379 PolarHBondContact NE2-OE1 3.12Å; H377-F382 AromaticContact CD2-CE2 3.83Å
378	K	91.4	Very high	94.1	Very high	14 Å²	14	27.8 Å²	27.8	6%	0.061	14%	0.137	C	C	.	.			trans	-135.1	135.4	-172.6	-60.7	-173.7	175.5	63.6	0	109.7	Q297 P298 W301 Y302 S373 L375	Q297-K378 HydrophobicContact CB-CB 4.26Å; Q297-K378 HydrophobicContact CB-CD 3.91Å; Q297-K378 HydrophobicContact CB-CG 4.26Å; Q297-K378 PolarHBondContact O-NZ 3.14Å; P298-K378 VanDerWaalsContact O-CE 3.23Å; P298-K378 WeakPolarHBondContact O-CE 3.49Å; P298-K378 PolarHBondContact O-NZ 3.46Å; W301-K378 HydrophobicContact CB-CD 3.93Å; W301-K378 HydrophobicContact CD2-CD 4.49Å; W301-K378 HydrophobicContact CE3-CB 3.89Å; W301-K378 HydrophobicContact CE3-CD 4Å; W301-K378 HydrophobicContact CG-CD 4.5Å; W301-K378 HydrophobicContact CZ3-CB 4.12Å; Y302-K378 HydrophobicContact CD2-CD 3.7Å; Y302-K378 HydrophobicContact CD2-CG 4.16Å; Y302-K378 HydrophobicContact CE1-CB 4.41Å; Y302-K378 HydrophobicContact CE2-CB 3.73Å; Y302-K378 HydrophobicContact CE2-CD 3.62Å; Y302-K378 HydrophobicContact CE2-CG 3.53Å; Y302-K378 HydrophobicContact CG-CD 4.46Å; Y302-K378 WeakPolarHBondContact OH-CA 3.36Å; S373-K378 WeakPolarHBondContact O-CE 3.11Å; S373-K378 PolarHBondContact O-NZ 2.95Å; S373-K378 VanDerWaalsContact O-NZ 3.11Å; L375-K378 WeakPolarHBondContact O-CE 3.31Å; L375-K378 PolarHBondContact O-NZ 3Å
379	E	93.3	Very high	94.2	Very high	32 Å²	32	28 Å²	28	15%	0.15	14%	0.138	C	C	.	.			trans	-139.1	149.9	171.6	-65.5	-166.8	-135.2	0	0	110.7	Y302 H377 R381 F382	Y302-E379 WeakPolarHBondContact CE1-O 3.31Å; Y302-E379 PolarHBondContact OH-N 3.46Å; Y302-E379 PolarHBondContact OH-O 3.25Å; H377-E379 IonicContact CE1-OE1 3.55Å; H377-E379 IonicContact NE2-OE1 3.61Å; H377-E379 PolarHBondContact NE2-OE1 3.12Å; E379-R381 HydrophobicContact CB-CG 4.1Å; E379-R381 VanDerWaalsContact CD-NH1 3.28Å; E379-R381 PolarHBondContact O-N 3.49Å; E379-R381 IonicContact OE1-CZ 2.81Å; E379-R381 IonicContact OE1-NE 2.8Å; E379-R381 IonicContact OE1-NH1 2.75Å; E379-R381 PolarHBondContact OE1-NH1 3.43Å; E379-R381 VanDerWaalsContact OE1-NH1 3.16Å; E379-R381 IonicContact OE1-NH2 2.83Å; E379-R381 PolarHBondContact OE1-NH2 2.95Å; E379-R381 WeakPolarHBondContact OE2-CD 3.5Å; E379-R381 IonicContact OE2-CZ 2.89Å; E379-R381 IonicContact OE2-NE 3.09Å; E379-R381 PolarHBondContact OE2-NE 3.23Å; E379-R381 IonicContact OE2-NH1 3.2Å; E379-R381 PolarHBondContact OE2-NH1 3.07Å; E379-R381 IonicContact OE2-NH2 2.71Å; E379-R381 PolarHBondContact OE2-NH2 3.32Å; E379-F382 HydrophobicContact CB-CD1 4.4Å; E379-F382 HydrophobicContact CB-CD2 3.99Å; E379-F382 HydrophobicContact CB-CE1 4.25Å; E379-F382 HydrophobicContact CB-CE2 3.82Å; E379-F382 HydrophobicContact CB-CG 4.25Å; E379-F382 HydrophobicContact CB-CZ 3.95Å; E379-F382 HydrophobicContact CG-CE2 3.91Å; E379-F382 HydrophobicContact CG-CZ 3.87Å; E379-F382 PolarHBondContact O-N 3.48Å
380	F	95.5	Very high	94.3	Very high	62 Å²	62	27.2 Å²	27.2	27%	0.272	13%	0.134	S	C	.	.	G	3₁₀ helix	trans	-57.7	-37.3	177.5	-60	-74.6	0	0	0	112.1	F133 W301 G306 A309 M310 F382 I383 F384	F133-F380 HydrophobicContact CE1-CB 4.44Å; F133-F380 HydrophobicContact CE2-CB 3.64Å; F133-F380 HydrophobicContact CE2-CG 4.29Å; F133-F380 HydrophobicContact CZ-CB 3.48Å; F133-F380 VanDerWaalsContact CZ-CB 3.48Å; W301-F380 AromaticContact CH2-CD1 3.75Å; W301-F380 HydrophobicContact CH2-CD1 3.75Å; W301-F380 HydrophobicContact CH2-CD2 4.31Å; W301-F380 AromaticContact CH2-CE1 3.51Å; W301-F380 HydrophobicContact CH2-CE1 3.51Å; W301-F380 HydrophobicContact CH2-CE2 4.06Å; W301-F380 HydrophobicContact CH2-CG 4.18Å; W301-F380 AromaticContact CH2-CZ 3.66Å; W301-F380 HydrophobicContact CH2-CZ 3.66Å; W301-F380 AromaticContact CZ2-CE1 3.93Å; W301-F380 HydrophobicContact CZ2-CE1 3.93Å; W301-F380 HydrophobicContact CZ2-CE2 4.33Å; W301-F380 AromaticContact CZ2-CZ 3.75Å; W301-F380 HydrophobicContact CZ2-CZ 3.75Å; W301-F380 HydrophobicContact CZ3-CD1 4.42Å; W301-F380 HydrophobicContact CZ3-CE1 4.45Å; G306-F380 WeakPolarHBondContact O-CD1 3.22Å; G306-F380 VanDerWaalsContact O-CE1 3.31Å; G306-F380 WeakPolarHBondContact O-CE1 3.47Å; A309-F380 HydrophobicContact CB-CE1 3.95Å; A309-F380 HydrophobicContact CB-CZ 4.41Å; M310-F380 WeakPolarHBondContact CE-O 3.36Å; M310-F380 HydrophobicContact CG-CB 4.04Å; M310-F380 HydrophobicContact CG-CD1 3.57Å; M310-F380 HydrophobicContact CG-CE1 4.39Å; M310-F380 HydrophobicContact CG-CG 4.18Å; M310-F380 HydrophobicContact SD-CB 3.79Å; M310-F380 HydrophobicContact SD-CD1 3.82Å; M310-F380 HydrophobicContact SD-CG 4.31Å; F380-F382 PolarHBondContact O-N 3.4Å; F380-I383 PolarHBondContact O-N 2.92Å; F380-F384 PolarHBondContact O-N 3.37Å
381	R	95.2	Very high	94.4	Very high	9 Å²	9	23.5 Å²	23.5	3%	0.034	12%	0.115	C	C	.	.	G	3₁₀ helix	trans	-64	-24.1	-177.1	70.6	-176.7	-167.6	-127.6	-3.9	113.9	Y30 D33 N144 E379 F384	Y30-R381 HydrophobicContact CE1-CB 4.1Å; D33-R381 IonicContact OD2-CZ 3.47Å; D33-R381 VanDerWaalsContact OD2-CZ 3.31Å; D33-R381 IonicContact OD2-NH1 3.95Å; D33-R381 IonicContact OD2-NH2 3.4Å; D33-R381 PolarHBondContact OD2-NH2 3.46Å; N144-R381 HydrophobicContact CB-CB 4.22Å; N144-R381 HydrophobicContact CB-CG 4.5Å; N144-R381 WeakPolarHBondContact OD1-CD 3.47Å; N144-R381 PolarHBondContact OD1-NE 2.91Å; E379-R381 HydrophobicContact CB-CG 4.1Å; E379-R381 VanDerWaalsContact CD-NH1 3.28Å; E379-R381 PolarHBondContact O-N 3.49Å; E379-R381 IonicContact OE1-CZ 2.81Å; E379-R381 IonicContact OE1-NE 2.8Å; E379-R381 IonicContact OE1-NH1 2.75Å; E379-R381 PolarHBondContact OE1-NH1 3.43Å; E379-R381 VanDerWaalsContact OE1-NH1 3.16Å; E379-R381 IonicContact OE1-NH2 2.83Å; E379-R381 PolarHBondContact OE1-NH2 2.95Å; E379-R381 WeakPolarHBondContact OE2-CD 3.5Å; E379-R381 IonicContact OE2-CZ 2.89Å; E379-R381 IonicContact OE2-NE 3.09Å; E379-R381 PolarHBondContact OE2-NE 3.23Å; E379-R381 IonicContact OE2-NH1 3.2Å; E379-R381 PolarHBondContact OE2-NH1 3.07Å; E379-R381 IonicContact OE2-NH2 2.71Å; E379-R381 PolarHBondContact OE2-NH2 3.32Å; R381-F384 WeakPolarHBondContact O-CB 3.45Å; R381-F384 PolarHBondContact O-N 2.94Å
382	F	95.4	Very high	94.6	Very high	24 Å²	24	22.1 Å²	22.1	11%	0.105	11%	0.106	C	C	.	.	G	3₁₀ helix	trans	-70.9	-34.4	-179.1	-60.5	-21.1	0	0	0	113	Y302 Y372 H377 E379 F380	Y302-F382 WeakPolarHBondContact OH-CD2 3.29Å; Y372-F382 HydrophobicContact CD1-CB 3.78Å; Y372-F382 HydrophobicContact CD1-CD2 4.46Å; Y372-F382 HydrophobicContact CD1-CG 4.44Å; Y372-F382 HydrophobicContact CE1-CB 3.65Å; Y372-F382 HydrophobicContact CE1-CG 4.27Å; Y372-F382 VanDerWaalsContact CE2-O 3.32Å; Y372-F382 WeakPolarHBondContact CE2-O 3.41Å; Y372-F382 HydrophobicContact CG-CB 4.39Å; Y372-F382 PolarHBondContact OH-O 3.19Å; H377-F382 AromaticContact CD2-CE2 3.83Å; E379-F382 HydrophobicContact CB-CD1 4.4Å; E379-F382 HydrophobicContact CB-CD2 3.99Å; E379-F382 HydrophobicContact CB-CE1 4.25Å; E379-F382 HydrophobicContact CB-CE2 3.82Å; E379-F382 HydrophobicContact CB-CG 4.25Å; E379-F382 HydrophobicContact CB-CZ 3.95Å; E379-F382 HydrophobicContact CG-CE2 3.91Å; E379-F382 HydrophobicContact CG-CZ 3.87Å; E379-F382 PolarHBondContact O-N 3.48Å; F380-F382 PolarHBondContact O-N 3.4Å
383	I	96.8	Very high	94.8	Very high	0 Å²	0	21.7 Å²	21.7	0%	0	10%	0.104	C	C	.	.	G	3₁₀ helix	trans	-96.9	8.6	177.2	64.9	162.5	0	0	0	112.4	Y302 F307 M310 I368 Y372 F380 P385 S386	Y302-I383 HydrophobicContact CD1-CD1 3.41Å; Y302-I383 VanDerWaalsContact CD1-CD1 3.41Å; Y302-I383 HydrophobicContact CD1-CG1 3.9Å; Y302-I383 HydrophobicContact CD1-CG2 4.01Å; Y302-I383 HydrophobicContact CE1-CB 4.41Å; Y302-I383 HydrophobicContact CE1-CD1 3.85Å; Y302-I383 HydrophobicContact CE1-CG1 3.78Å; Y302-I383 HydrophobicContact CE1-CG2 3.78Å; Y302-I383 HydrophobicContact CE2-CG2 4.35Å; Y302-I383 HydrophobicContact CG-CD1 4.23Å; Y302-I383 HydrophobicContact CG-CG2 4.35Å; F307-I383 HydrophobicContact CB-CD1 3.94Å; F307-I383 HydrophobicContact CD2-CD1 3.73Å; F307-I383 HydrophobicContact CG-CD1 4.24Å; M310-I383 HydrophobicContact CE-CD1 4.48Å; M310-I383 HydrophobicContact CE-CG1 3.98Å; M310-I383 HydrophobicContact SD-CD1 3.72Å; M310-I383 HydrophobicContact SD-CG1 3.63Å; I368-I383 HydrophobicContact CG2-CB 4.32Å; I368-I383 HydrophobicContact CG2-CG2 4.15Å; Y372-I383 HydrophobicContact CD2-CG2 3.74Å; Y372-I383 HydrophobicContact CG-CG2 3.98Å; F380-I383 PolarHBondContact O-N 2.92Å; I383-P385 VanDerWaalsContact C-N 3.28Å; I383-S386 WeakPolarHBondContact O-CB 3.29Å; I383-S386 PolarHBondContact O-N 3.35Å; I383-S386 PolarHBondContact O-OG 3.42Å
384	F	97.5	Very high	95	Very high	1 Å²	1	21.2 Å²	21.2	0%	0.004	10%	0.1	C	C	.	.	G	3₁₀ helix	trans	-53.8	-37.3	179	-169.8	-148.7	0	0	0	113.8	F133 C137 W148 M310 F380 R381 S386 I387	F133-F384 AromaticContact CD1-CD2 3.67Å; F133-F384 HydrophobicContact CD1-CD2 3.67Å; F133-F384 AromaticContact CD1-CE2 3.77Å; F133-F384 HydrophobicContact CD1-CE2 3.77Å; F133-F384 HydrophobicContact CE1-CB 4.28Å; F133-F384 AromaticContact CE1-CD2 3.56Å; F133-F384 HydrophobicContact CE1-CD2 3.56Å; F133-F384 HydrophobicContact CE1-CE2 4.03Å; F133-F384 AromaticContact CE1-CG 3.96Å; F133-F384 HydrophobicContact CE1-CG 3.96Å; C137-F384 HydrophobicContact CB-CD1 4.43Å; C137-F384 HydrophobicContact CB-CE1 3.87Å; C137-F384 HydrophobicContact CB-CZ 3.95Å; W148-F384 HydrophobicContact CB-CD1 3.53Å; W148-F384 HydrophobicContact CB-CE1 3.81Å; W148-F384 HydrophobicContact CB-CG 4.22Å; W148-F384 AromaticContact CD1-CD1 3.72Å; W148-F384 AromaticContact CD1-CD2 3.85Å; W148-F384 AromaticContact CD1-CE1 3.77Å; W148-F384 AromaticContact CD1-CE2 3.89Å; W148-F384 AromaticContact CD1-CG 3.76Å; W148-F384 AromaticContact CD1-CZ 3.85Å; W148-F384 HydrophobicContact CD2-CD1 4.15Å; W148-F384 AromaticContact CD2-CE1 3.54Å; W148-F384 HydrophobicContact CD2-CE1 3.54Å; W148-F384 HydrophobicContact CD2-CE2 4.47Å; W148-F384 AromaticContact CD2-CZ 3.72Å; W148-F384 HydrophobicContact CD2-CZ 3.72Å; W148-F384 AromaticContact CE2-CE1 3.92Å; W148-F384 AromaticContact CE2-CZ 3.56Å; W148-F384 HydrophobicContact CE3-CE1 4.04Å; W148-F384 HydrophobicContact CE3-CZ 4.33Å; W148-F384 AromaticContact CG-CD1 3.52Å; W148-F384 HydrophobicContact CG-CD1 3.52Å; W148-F384 HydrophobicContact CG-CD2 4.44Å; W148-F384 AromaticContact CG-CE1 3.44Å; W148-F384 HydrophobicContact CG-CE1 3.44Å; W148-F384 VanDerWaalsContact CG-CE1 3.44Å; W148-F384 HydrophobicContact CG-CE2 4.37Å; W148-F384 HydrophobicContact CG-CG 4.04Å; W148-F384 AromaticContact CG-CZ 3.88Å; W148-F384 HydrophobicContact CG-CZ 3.88Å; W148-F384 HydrophobicContact CZ2-CZ 4.04Å; W148-F384 AromaticContact NE1-CE2 3.63Å; W148-F384 AromaticContact NE1-CZ 3.62Å; M310-F384 HydrophobicContact CE-CB 4.45Å; M310-F384 HydrophobicContact CE-CD2 4.35Å; F380-F384 PolarHBondContact O-N 3.37Å; R381-F384 WeakPolarHBondContact O-CB 3.45Å; R381-F384 PolarHBondContact O-N 2.94Å; F384-S386 PolarHBondContact O-N 3.32Å; F384-I387 HydrophobicContact CD2-CB 4.24Å; F384-I387 HydrophobicContact CD2-CG1 3.92Å; F384-I387 HydrophobicContact CE2-CB 4.44Å; F384-I387 HydrophobicContact CE2-CG1 4.39Å; F384-I387 WeakPolarHBondContact O-CB 3.37Å; F384-I387 PolarHBondContact O-N 2.71Å
385	P	97.3	Very high	95.3	Very high	6 Å²	6	13.4 Å²	13.4	4%	0.039	7%	0.066	C	C	.	.	G	3₁₀ helix	trans	-57.1	-15.8	173.4	-28.3	37.7	0	0	0	115.9	E147 C151 I383 P388	E147-P385 HydrophobicContact CG-CG 4.13Å; C151-P385 HydrophobicContact CB-CB 4.15Å; I383-P385 VanDerWaalsContact C-N 3.28Å; P385-P388 WeakPolarHBondContact O-CD 3.2Å; P385-P388 WeakPolarHBondContact O-CG 3.18Å
386	S	97.1	Very high	95.7	Very high	0 Å²	0	10.4 Å²	10.4	0%	0	5%	0.051	C	C	.	.	G	3₁₀ helix	trans	-82.5	-21.5	176.8	70	0	0	0	0	114.1	F307 I383 F384 L389 A390	F307-S386 WeakPolarHBondContact CE2-OG 3.34Å; I383-S386 WeakPolarHBondContact O-CB 3.29Å; I383-S386 PolarHBondContact O-N 3.35Å; I383-S386 PolarHBondContact O-OG 3.42Å; F384-S386 PolarHBondContact O-N 3.32Å; S386-L389 WeakPolarHBondContact O-CB 3.32Å; S386-L389 PolarHBondContact O-N 3.4Å; S386-A390 PolarHBondContact O-N 2.98Å
387	I	97.8	Very high	96.3	Very high	0 Å²	0	8.9 Å²	8.9	0%	0	4%	0.041	C	C	.	.	H	α-helix	trans	-56.9	-48.2	-180	-67.1	-66.8	0	0	0	113.9	F307 M310 L311 F384 L389 A390 M391	F307-I387 HydrophobicContact CD2-CD1 4.32Å; F307-I387 HydrophobicContact CE2-CD1 3.83Å; M310-I387 HydrophobicContact CB-CD1 3.79Å; M310-I387 HydrophobicContact CE-CD1 3.82Å; M310-I387 HydrophobicContact CE-CG1 3.61Å; L311-I387 HydrophobicContact CD2-CD1 3.77Å; L311-I387 HydrophobicContact CG-CD1 4.39Å; F384-I387 HydrophobicContact CD2-CB 4.24Å; F384-I387 HydrophobicContact CD2-CG1 3.92Å; F384-I387 HydrophobicContact CE2-CB 4.44Å; F384-I387 HydrophobicContact CE2-CG1 4.39Å; F384-I387 WeakPolarHBondContact O-CB 3.37Å; F384-I387 PolarHBondContact O-N 2.71Å; I387-L389 PolarHBondContact O-N 3.06Å; I387-A390 PolarHBondContact O-N 3.32Å; I387-M391 HydrophobicContact CG2-CE 4.25Å; I387-M391 HydrophobicContact CG2-CG 4.05Å; I387-M391 VanDerWaalsContact O-CG 3.31Å; I387-M391 WeakPolarHBondContact O-CG 3.31Å; I387-M391 PolarHBondContact O-N 3.1Å
388	P	98.1	Very high	96.7	Very high	3 Å²	3	8.3 Å²	8.3	2%	0.019	4%	0.04	C	C	.	.	H	α-helix	trans	-58.9	-33.2	178.7	22.1	-34.6	0	0	0	113.1	L108 I152 P385 M391 Y392	L108-P388 HydrophobicContact CD1-CB 3.95Å; L108-P388 HydrophobicContact CD2-CB 4.31Å; I152-P388 HydrophobicContact CD1-CB 3.88Å; I152-P388 HydrophobicContact CD1-CG 3.97Å; I152-P388 HydrophobicContact CG1-CB 3.74Å; I152-P388 HydrophobicContact CG1-CG 3.64Å; P385-P388 WeakPolarHBondContact O-CD 3.2Å; P385-P388 WeakPolarHBondContact O-CG 3.18Å; P388-M391 PolarHBondContact O-N 3.02Å; P388-Y392 PolarHBondContact O-N 3.02Å
389	L	97.9	Very high	96.9	Very high	8 Å²	8	7.9 Å²	7.9	4%	0.042	4%	0.038	C	C	.	.	H	α-helix	trans	-67.5	-40.6	175.6	-53.5	-178.4	0	0	0	111.3	L155 C361 V364 M365 S386 I387 Y392 F393	L155-L389 HydrophobicContact CD1-CD2 3.89Å; C361-L389 HydrophobicContact CB-CD2 4.36Å; V364-L389 HydrophobicContact CB-CD1 4.11Å; V364-L389 HydrophobicContact CG1-CD1 3.74Å; M365-L389 HydrophobicContact CB-CD1 4.24Å; S386-L389 WeakPolarHBondContact O-CB 3.32Å; S386-L389 PolarHBondContact O-N 3.4Å; I387-L389 PolarHBondContact O-N 3.06Å; L389-Y392 WeakPolarHBondContact O-CB 3.34Å; L389-Y392 PolarHBondContact O-N 3.37Å; L389-F393 WeakPolarHBondContact O-CD2 3.27Å
390	A	98.3	Very high	96.9	Very high	0 Å²	0	6.6 Å²	6.6	0%	0	3%	0.032	C	C	.	.	H	α-helix	trans	-68.2	-38.4	174.9	0	0	0	0	0	112.8	F307 L311 V318 M365 S386 I387 Y392 F393 S394	F307-A390 HydrophobicContact CE1-CB 4.45Å; F307-A390 HydrophobicContact CZ-CB 3.8Å; L311-A390 HydrophobicContact CD1-CB 4.49Å; L311-A390 HydrophobicContact CD2-CB 3.72Å; V318-A390 HydrophobicContact CG1-CB 4.37Å; V318-A390 HydrophobicContact CG2-CB 3.98Å; V318-A390 WeakPolarHBondContact CG2-O 3.42Å; M365-A390 HydrophobicContact SD-CB 4.11Å; S386-A390 PolarHBondContact O-N 2.98Å; I387-A390 PolarHBondContact O-N 3.32Å; A390-Y392 PolarHBondContact O-N 3.48Å; A390-F393 WeakPolarHBondContact O-CB 3.49Å; A390-F393 PolarHBondContact O-N 3.42Å; A390-S394 PolarHBondContact O-N 2.91Å; A390-S394 VanDerWaalsContact O-N 3.09Å; A390-S394 PolarHBondContact O-OG 3.39Å
391	M	98.4	Very high	96.7	Very high	0 Å²	0	6.9 Å²	6.9	0%	0	3%	0.033	C	C	.	.	H	α-helix	trans	-63.6	-31.3	177.1	-64.2	-59.8	115	0	0	112.3	T124 H127 H128 N131 L311 Q314 I387 P388 F393 S394 G395	T124-M391 HydrophobicContact CG2-CB 4.2Å; H127-M391 VanDerWaalsContact C-SD 3.58Å; H127-M391 HydrophobicContact CB-CB 4.5Å; H127-M391 HydrophobicContact CB-SD 3.76Å; H127-M391 VanDerWaalsContact O-SD 3.4Å; H128-M391 HydrophobicContact CB-CB 4.11Å; H128-M391 HydrophobicContact CB-CG 4.03Å; N131-M391 HydrophobicContact CB-CE 4.41Å; N131-M391 HydrophobicContact CB-SD 4.05Å; L311-M391 HydrophobicContact CD2-CE 3.3Å; Q314-M391 HydrophobicContact CB-CE 3.85Å; Q314-M391 HydrophobicContact CB-SD 4.46Å; Q314-M391 HydrophobicContact CG-CE 3.98Å; Q314-M391 HydrophobicContact CG-SD 3.97Å; I387-M391 HydrophobicContact CG2-CE 4.25Å; I387-M391 HydrophobicContact CG2-CG 4.05Å; I387-M391 VanDerWaalsContact O-CG 3.31Å; I387-M391 WeakPolarHBondContact O-CG 3.31Å; I387-M391 PolarHBondContact O-N 3.1Å; P388-M391 PolarHBondContact O-N 3.02Å; M391-F393 VanDerWaalsContact C-N 3.32Å; M391-F393 PolarHBondContact O-N 3.09Å; M391-S394 PolarHBondContact O-N 3.09Å; M391-G395 PolarHBondContact O-N 3.34Å
392	Y	98.1	Very high	96.5	Very high	1 Å²	1	11.2 Å²	11.2	0%	0.004	6%	0.061	C	C	.	.	H	α-helix	trans	-60.1	-42.4	171.5	173.9	-143.1	0	0	0	112	I112 L115 S116 I120 C358 P388 L389 A390 G395 I396	I112-Y392 HydrophobicContact CD1-CD1 4.09Å; I112-Y392 HydrophobicContact CD1-CD2 3.52Å; I112-Y392 HydrophobicContact CD1-CE2 4.03Å; I112-Y392 HydrophobicContact CD1-CG 3.54Å; I112-Y392 HydrophobicContact CG1-CD2 4.16Å; I112-Y392 HydrophobicContact CG1-CG 4.49Å; I112-Y392 HydrophobicContact CG2-CD2 3.7Å; I112-Y392 HydrophobicContact CG2-CE2 3.8Å; L115-Y392 HydrophobicContact CD1-CE1 4.36Å; S116-Y392 PolarHBondContact OG-OH 3.35Å; I120-Y392 HydrophobicContact CG2-CD2 4.04Å; I120-Y392 HydrophobicContact CG2-CE2 3.83Å; C358-Y392 PolarHBondContact SG-OH 3Å; P388-Y392 PolarHBondContact O-N 3.02Å; L389-Y392 WeakPolarHBondContact O-CB 3.34Å; L389-Y392 PolarHBondContact O-N 3.37Å; A390-Y392 PolarHBondContact O-N 3.48Å; Y392-G395 PolarHBondContact O-N 3.22Å; Y392-I396 HydrophobicContact CD2-CD1 4.01Å; Y392-I396 HydrophobicContact CD2-CG1 4.15Å; Y392-I396 HydrophobicContact CE1-CD1 4.29Å; Y392-I396 HydrophobicContact CE2-CD1 3.65Å; Y392-I396 HydrophobicContact CE2-CG1 3.91Å; Y392-I396 HydrophobicContact CG-CD1 4.49Å; Y392-I396 WeakPolarHBondContact O-CG1 3.25Å; Y392-I396 PolarHBondContact O-N 3.09Å
393	F	98	Very high	96.2	Very high	0 Å²	0	15.7 Å²	15.7	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-64.1	-42.6	175.7	-55.2	-26.8	0	0	0	112	V318 F321 C361 I362 M365 L389 A390 M391 G395 I396 I397	V318-F393 HydrophobicContact CG1-CD2 4.3Å; F321-F393 HydrophobicContact CB-CB 3.75Å; F321-F393 HydrophobicContact CB-CG 4.49Å; F321-F393 HydrophobicContact CD1-CB 3.49Å; F321-F393 VanDerWaalsContact CD1-CB 3.49Å; F321-F393 AromaticContact CD1-CD1 3.4Å; F321-F393 HydrophobicContact CD1-CD1 3.4Å; F321-F393 AromaticContact CD1-CD2 3.89Å; F321-F393 HydrophobicContact CD1-CD2 3.89Å; F321-F393 HydrophobicContact CD1-CE1 4.08Å; F321-F393 AromaticContact CD1-CG 3.3Å; F321-F393 HydrophobicContact CD1-CG 3.3Å; F321-F393 HydrophobicContact CD2-CB 4.25Å; F321-F393 HydrophobicContact CE1-CB 4.18Å; F321-F393 AromaticContact CE1-CD1 3.14Å; F321-F393 HydrophobicContact CE1-CD1 3.14Å; F321-F393 HydrophobicContact CE1-CD2 4.27Å; F321-F393 AromaticContact CE1-CE1 3.48Å; F321-F393 HydrophobicContact CE1-CE1 3.48Å; F321-F393 VanDerWaalsContact CE1-CE1 3.48Å; F321-F393 AromaticContact CE1-CG 3.6Å; F321-F393 HydrophobicContact CE1-CG 3.6Å; F321-F393 HydrophobicContact CE1-CZ 4.17Å; F321-F393 HydrophobicContact CE2-CD1 4.36Å; F321-F393 HydrophobicContact CG-CB 3.54Å; F321-F393 HydrophobicContact CG-CD1 4.11Å; F321-F393 AromaticContact CG-CG 3.91Å; F321-F393 HydrophobicContact CG-CG 3.91Å; F321-F393 AromaticContact CZ-CD1 3.71Å; F321-F393 HydrophobicContact CZ-CD1 3.71Å; F321-F393 HydrophobicContact CZ-CE1 4.11Å; F321-F393 HydrophobicContact CZ-CG 4.44Å; C361-F393 HydrophobicContact CB-CE1 3.91Å; C361-F393 HydrophobicContact CB-CZ 3.73Å; I362-F393 HydrophobicContact CB-CZ 4.47Å; I362-F393 HydrophobicContact CG1-CE1 4.21Å; I362-F393 HydrophobicContact CG1-CE2 4.06Å; I362-F393 HydrophobicContact CG1-CZ 3.59Å; M365-F393 HydrophobicContact CE-CD2 4.32Å; M365-F393 HydrophobicContact CE-CE2 3.68Å; M365-F393 HydrophobicContact SD-CD2 4.45Å; M365-F393 HydrophobicContact SD-CE2 3.87Å; L389-F393 WeakPolarHBondContact O-CD2 3.27Å; A390-F393 WeakPolarHBondContact O-CB 3.49Å; A390-F393 PolarHBondContact O-N 3.42Å; M391-F393 VanDerWaalsContact C-N 3.32Å; M391-F393 PolarHBondContact O-N 3.09Å; F393-G395 VanDerWaalsContact C-N 3.31Å; F393-G395 PolarHBondContact O-N 3.08Å; F393-I396 PolarHBondContact O-N 3.36Å; F393-I397 PolarHBondContact O-N 3.44Å; F393-I397 VanDerWaalsContact O-N 3.07Å
394	S	98.3	Very high	95.7	Very high	0 Å²	0	18.3 Å²	18.3	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-59.6	-41.3	173.1	-58.3	0	0	0	0	112.1	V318 A390 M391 I397 S398	V318-S394 WeakPolarHBondContact CG2-OG 3.43Å; A390-S394 PolarHBondContact O-N 2.91Å; A390-S394 VanDerWaalsContact O-N 3.09Å; A390-S394 PolarHBondContact O-OG 3.39Å; M391-S394 PolarHBondContact O-N 3.09Å; S394-I397 PolarHBondContact O-N 3.39Å; S394-S398 PolarHBondContact O-N 3.33Å; S394-S398 PolarHBondContact O-OG 3.49Å
395	G	97.8	Very high	95	Very high	0 Å²	0	19.8 Å²	19.8	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-61.3	-43.3	176.3	0	0	0	0	0	113	M391 Y392 F393 S398 V399	M391-G395 PolarHBondContact O-N 3.34Å; Y392-G395 PolarHBondContact O-N 3.22Å; F393-G395 VanDerWaalsContact C-N 3.31Å; F393-G395 PolarHBondContact O-N 3.08Å; G395-S398 PolarHBondContact O-N 3.07Å; G395-V399 WeakPolarHBondContact O-CG2 3.18Å; G395-V399 PolarHBondContact O-N 3.41Å; G395-V399 VanDerWaalsContact O-N 3.13Å
396	I	96.5	Very high	93.9	Very high	0 Å²	0	26.7 Å²	26.7	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-61	-48.9	176.3	-67.3	167.7	0	0	0	111	I120 F321 F332 V333 L336 Y392 F393 S398 V399 W400	I120-I396 HydrophobicContact CD1-CG1 4.24Å; I120-I396 HydrophobicContact CG2-CG1 3.69Å; F321-I396 HydrophobicContact CD2-CB 4.1Å; F321-I396 HydrophobicContact CD2-CD1 4.21Å; F321-I396 HydrophobicContact CD2-CG2 3.95Å; F321-I396 HydrophobicContact CE2-CB 4.11Å; F321-I396 HydrophobicContact CE2-CD1 3.49Å; F321-I396 VanDerWaalsContact CE2-CD1 3.49Å; F321-I396 HydrophobicContact CE2-CG1 4.41Å; F321-I396 HydrophobicContact CE2-CG2 3.83Å; F321-I396 HydrophobicContact CZ-CD1 3.95Å; F332-I396 HydrophobicContact CE2-CG2 4.24Å; V333-I396 HydrophobicContact CG1-CD1 4.01Å; V333-I396 HydrophobicContact CG1-CG1 4.37Å; V333-I396 HydrophobicContact CG1-CG2 4.05Å; V333-I396 HydrophobicContact CG2-CG2 4.41Å; L336-I396 HydrophobicContact CD1-CG2 3.51Å; Y392-I396 HydrophobicContact CD2-CD1 4.01Å; Y392-I396 HydrophobicContact CD2-CG1 4.15Å; Y392-I396 HydrophobicContact CE1-CD1 4.29Å; Y392-I396 HydrophobicContact CE2-CD1 3.65Å; Y392-I396 HydrophobicContact CE2-CG1 3.91Å; Y392-I396 HydrophobicContact CG-CD1 4.49Å; Y392-I396 WeakPolarHBondContact O-CG1 3.25Å; Y392-I396 PolarHBondContact O-N 3.09Å; F393-I396 PolarHBondContact O-N 3.36Å; I396-S398 VanDerWaalsContact C-N 3.33Å; I396-S398 PolarHBondContact O-N 3.05Å; I396-V399 PolarHBondContact O-N 2.94Å; I396-W400 PolarHBondContact O-N 3.43Å
397	I	96.7	Very high	92.3	Very high	0 Å²	0	34 Å²	34	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-67.3	-35.3	-177.9	-70.2	-58.4	0	0	0	111.8	L317 T320 F321 M324 F393 S394 V399 W400 F401	L317-I397 HydrophobicContact CB-CG2 4.39Å; L317-I397 HydrophobicContact CD2-CG2 3.81Å; T320-I397 HydrophobicContact CG2-CD1 4.11Å; T320-I397 HydrophobicContact CG2-CG2 4.28Å; F321-I397 HydrophobicContact CB-CD1 4.16Å; F321-I397 HydrophobicContact CB-CG1 3.6Å; F321-I397 HydrophobicContact CD2-CD1 4.3Å; F321-I397 HydrophobicContact CD2-CG1 4.15Å; F321-I397 HydrophobicContact CG-CG1 4.39Å; M324-I397 HydrophobicContact SD-CD1 3.7Å; F393-I397 PolarHBondContact O-N 3.44Å; F393-I397 VanDerWaalsContact O-N 3.07Å; S394-I397 PolarHBondContact O-N 3.39Å; I397-V399 PolarHBondContact O-N 2.97Å; I397-W400 PolarHBondContact O-N 3.38Å; I397-F401 HydrophobicContact CG2-CD2 3.46Å; I397-F401 VanDerWaalsContact CG2-CD2 3.46Å; I397-F401 HydrophobicContact CG2-CE2 3.21Å; I397-F401 HydrophobicContact CG2-CZ 4.23Å; I397-F401 WeakPolarHBondContact O-CD2 3.2Å; I397-F401 PolarHBondContact O-N 3.03Å
398	S	95.8	Very high	90.4	Very high	15 Å²	15	38.5 Å²	38.5	11%	0.105	19%	0.194	C	C	.	.	H	α-helix	trans	-60.9	-43.9	171.4	-72.3	0	0	0	0	112.5	H127 S394 G395 I396 W400 F401 V402	H127-S398 PolarHBondContact NE2-OG 3.45Å; S394-S398 PolarHBondContact O-N 3.33Å; S394-S398 PolarHBondContact O-OG 3.49Å; G395-S398 PolarHBondContact O-N 3.07Å; I396-S398 VanDerWaalsContact C-N 3.33Å; I396-S398 PolarHBondContact O-N 3.05Å; S398-W400 VanDerWaalsContact C-N 3.32Å; S398-W400 PolarHBondContact O-N 3.4Å; S398-F401 PolarHBondContact O-N 3.2Å; S398-V402 WeakPolarHBondContact O-CB 3.42Å; S398-V402 VanDerWaalsContact O-CG2 3.25Å; S398-V402 WeakPolarHBondContact O-CG2 3.34Å; S398-V402 PolarHBondContact O-N 3.12Å
399	V	94.6	Very high	88.1	Confident	4 Å²	4	47.8 Å²	47.8	2%	0.024	23%	0.234	C	C	.	.	H	α-helix	trans	-63.8	-40	175	175.3	0	0	0	0	111.3	E119 I120 W123 L336 G395 I396 I397 V402 R403	E119-V399 HydrophobicContact CB-CG2 4.14Å; I120-V399 HydrophobicContact CB-CG2 4.47Å; I120-V399 HydrophobicContact CG1-CB 4.12Å; I120-V399 HydrophobicContact CG1-CG1 4.35Å; I120-V399 HydrophobicContact CG1-CG2 3.75Å; W123-V399 HydrophobicContact CB-CG2 4.43Å; W123-V399 VanDerWaalsContact CD1-CG2 3.46Å; W123-V399 HydrophobicContact CG-CG2 4.18Å; L336-V399 HydrophobicContact CD2-CG1 4.35Å; G395-V399 WeakPolarHBondContact O-CG2 3.18Å; G395-V399 PolarHBondContact O-N 3.41Å; G395-V399 VanDerWaalsContact O-N 3.13Å; I396-V399 PolarHBondContact O-N 2.94Å; I397-V399 PolarHBondContact O-N 2.97Å; V399-V402 PolarHBondContact O-N 3.44Å; V399-R403 HydrophobicContact CG1-CG 4.49Å; V399-R403 WeakPolarHBondContact O-CG 3.19Å; V399-R403 PolarHBondContact O-N 2.96Å
400	W	93	Very high	85.9	Confident	6 Å²	6	50.6 Å²	50.6	2%	0.023	25%	0.248	C	C	.	.	H	α-helix	trans	-60.3	-47.5	175.7	-174.5	92.8	0	0	0	111.8	M324 L336 I396 I397 S398 V402 R403 Y404 G405 L408 L411	M324-W400 HydrophobicContact CE-CD2 4.01Å; M324-W400 HydrophobicContact CE-CG 4.26Å; M324-W400 HydrophobicContact CE-CZ2 4.02Å; L336-W400 HydrophobicContact CD1-CB 4.2Å; L336-W400 HydrophobicContact CD2-CB 3.85Å; L336-W400 HydrophobicContact CD2-CG 4.24Å; I396-W400 PolarHBondContact O-N 3.43Å; I397-W400 PolarHBondContact O-N 3.38Å; S398-W400 VanDerWaalsContact C-N 3.32Å; S398-W400 PolarHBondContact O-N 3.4Å; W400-V402 PolarHBondContact O-N 3.15Å; W400-R403 PolarHBondContact O-N 2.71Å; W400-Y404 AromaticContact CD1-CD2 3.56Å; W400-Y404 AromaticContact CD1-CE2 3.94Å; W400-Y404 HydrophobicContact CD2-CD2 4.32Å; W400-Y404 HydrophobicContact CG-CD2 4Å; W400-Y404 AromaticContact NE1-CD2 3.54Å; W400-Y404 WeakPolarHBondContact O-CD2 3.44Å; W400-Y404 PolarHBondContact O-N 3.43Å; W400-G405 VanDerWaalsContact CZ3-O 3.29Å; W400-G405 WeakPolarHBondContact CZ3-O 3.47Å; W400-L408 HydrophobicContact CH2-CD2 3.73Å; W400-L408 HydrophobicContact CH2-CG 4.04Å; W400-L408 HydrophobicContact CZ2-CD2 3.91Å; W400-L411 HydrophobicContact CZ2-CD1 4.37Å
401	F	92.5	Very high	83.6	Confident	67 Å²	67	51.5 Å²	51.5	29%	0.294	25%	0.253	S	S	.	.	H	α-helix	trans	-63.9	-40.5	176.7	-79.8	-56.5	0	0	0	112.7	L317 I397 S398 R403 G405 L406	L317-F401 HydrophobicContact CD2-CD2 4.39Å; L317-F401 HydrophobicContact CD2-CE2 4.02Å; I397-F401 HydrophobicContact CG2-CD2 3.46Å; I397-F401 VanDerWaalsContact CG2-CD2 3.46Å; I397-F401 HydrophobicContact CG2-CE2 3.21Å; I397-F401 HydrophobicContact CG2-CZ 4.23Å; I397-F401 WeakPolarHBondContact O-CD2 3.2Å; I397-F401 PolarHBondContact O-N 3.03Å; S398-F401 PolarHBondContact O-N 3.2Å; F401-R403 VanDerWaalsContact C-N 3.29Å; F401-R403 PolarHBondContact O-N 3.01Å; F401-G405 WeakPolarHBondContact O-CA 3.18Å; F401-G405 PolarHBondContact O-N 3.33Å; F401-L406 HydrophobicContact CD1-CD2 4.48Å; F401-L406 HydrophobicContact CE1-CD2 3.83Å
402	V	91.6	Very high	81.2	Confident	101 Å²	101	58 Å²	58	61%	0.612	28%	0.283	S	S	*	.	H	α-helix	trans	-63	-37.5	177.3	169.4	0	0	0	0	111.2	W123 S398 V399 W400	W123-V402 HydrophobicContact CZ2-CG2 3.95Å; S398-V402 WeakPolarHBondContact O-CB 3.42Å; S398-V402 VanDerWaalsContact O-CG2 3.25Å; S398-V402 WeakPolarHBondContact O-CG2 3.34Å; S398-V402 PolarHBondContact O-N 3.12Å; V399-V402 PolarHBondContact O-N 3.44Å; W400-V402 PolarHBondContact O-N 3.15Å
403	R	88.6	Confident	78.9	Confident	118 Å²	118	61.3 Å²	61.3	45%	0.445	31%	0.306	S	S	.	.	H	α-helix	trans	-82.8	-41.3	-177.4	-72.6	-174.2	176.4	-148.9	-0.6	114.3	L336 V399 W400 F401	L336-R403 PolarHBondContact O-NE 3.37Å; L336-R403 PolarHBondContact O-NH1 2.93Å; L336-R403 PolarHBondContact O-NH2 3.47Å; L336-R403 VanDerWaalsContact O-NH2 3.17Å; V399-R403 HydrophobicContact CG1-CG 4.49Å; V399-R403 WeakPolarHBondContact O-CG 3.19Å; V399-R403 PolarHBondContact O-N 2.96Å; W400-R403 PolarHBondContact O-N 2.71Å; F401-R403 VanDerWaalsContact C-N 3.29Å; F401-R403 PolarHBondContact O-N 3.01Å
404	Y	86.9	Confident	76.6	Confident	54 Å²	54	65.7 Å²	65.7	21%	0.212	33%	0.327	C	S	.	.	H	α-helix	trans	-112.5	-8	-170.7	-57.7	-67.4	0	0	0	113.3	L336 W400 K407	L336-Y404 HydrophobicContact CD2-CD2 4.33Å; L336-Y404 HydrophobicContact CD2-CE2 3.73Å; W400-Y404 AromaticContact CD1-CD2 3.56Å; W400-Y404 AromaticContact CD1-CE2 3.94Å; W400-Y404 HydrophobicContact CD2-CD2 4.32Å; W400-Y404 HydrophobicContact CG-CD2 4Å; W400-Y404 AromaticContact NE1-CD2 3.54Å; W400-Y404 WeakPolarHBondContact O-CD2 3.44Å; W400-Y404 PolarHBondContact O-N 3.43Å; Y404-K407 WeakPolarHBondContact O-CB 3.17Å; Y404-K407 PolarHBondContact O-N 3.28Å
405	G	82.5	Confident	74.3	Confident	32 Å²	32	68.1 Å²	68.1	33%	0.33	34%	0.339	S	S	.	.	T	Hydrogen-bonded Turn	trans	57.4	-146.3	-171	0	0	0	0	0	111.4	W400 F401 K407	W400-G405 VanDerWaalsContact CZ3-O 3.29Å; W400-G405 WeakPolarHBondContact CZ3-O 3.47Å; F401-G405 WeakPolarHBondContact O-CA 3.18Å; F401-G405 PolarHBondContact O-N 3.33Å; G405-K407 VanDerWaalsContact C-N 3.25Å; G405-K407 PolarHBondContact O-N 3.43Å
406	L	74.3	Confident	71.7	Confident	151 Å²	151	70.7 Å²	70.7	79%	0.791	36%	0.355	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.9	5.9	172.2	-70.1	164.2	0	0	0	113	F401 L408	F401-L406 HydrophobicContact CD1-CD2 4.48Å; F401-L406 HydrophobicContact CE1-CD2 3.83Å; L406-L408 VanDerWaalsContact C-N 3.32Å; L406-L408 PolarHBondContact O-N 2.96Å
407	K	63.4	Low	69	Low	154 Å²	154	79.2 Å²	79.2	67%	0.67	39%	0.387	S	S	*	.			trans	-78.6	75.8	-173.6	-64	-176.5	178.9	178.8	0	111.6	Y404 G405 K409 I410	Y404-K407 WeakPolarHBondContact O-CB 3.17Å; Y404-K407 PolarHBondContact O-N 3.28Å; G405-K407 VanDerWaalsContact C-N 3.25Å; G405-K407 PolarHBondContact O-N 3.43Å; K407-K409 PolarHBondContact O-N 3.03Å; K407-I410 HydrophobicContact CB-CD1 4.48Å
408	L	57.4	Low	66.3	Low	95 Å²	95	84.8 Å²	84.8	50%	0.497	41%	0.408	S	S	.	.	T	Hydrogen-bonded Turn	trans	-59.8	-22.6	175.7	-79	160.1	0	0	0	114.1	W400 L406 I410 L411	W400-L408 HydrophobicContact CH2-CD2 3.73Å; W400-L408 HydrophobicContact CH2-CG 4.04Å; W400-L408 HydrophobicContact CZ2-CD2 3.91Å; L406-L408 VanDerWaalsContact C-N 3.32Å; L406-L408 PolarHBondContact O-N 2.96Å; L408-I410 PolarHBondContact O-N 3.31Å; L408-I410 VanDerWaalsContact O-N 3.13Å; L408-L411 PolarHBondContact O-N 3.41Å
409	K	49.2	Very low	63.8	Low	197 Å²	197	90.7 Å²	90.7	86%	0.857	43%	0.434	S	S	*	.	H	α-helix	trans	-59.7	-24.5	-175.5	-78.8	-173.5	175.3	-178.1	0	114.4	K407 L411	K407-K409 PolarHBondContact O-N 3.03Å; K409-L411 VanDerWaalsContact C-N 3.34Å
410	I	51.6	Low	60.9	Low	68 Å²	68	98.2 Å²	98.2	35%	0.349	46%	0.463	S	S	.	.	H	α-helix	trans	-73.4	-27.7	-177.5	-62.1	170.1	0	0	0	111.7	K407 L408 H412 S413 Q414	K407-I410 HydrophobicContact CB-CD1 4.48Å; L408-I410 PolarHBondContact O-N 3.31Å; L408-I410 VanDerWaalsContact O-N 3.13Å; I410-H412 PolarHBondContact O-N 3.19Å; I410-S413 PolarHBondContact O-N 2.79Å; I410-Q414 HydrophobicContact CG2-CG 4.42Å; I410-Q414 PolarHBondContact O-N 3.38Å
411	L	49.7	Very low	58.2	Low	18 Å²	18	104.9 Å²	104.9	9%	0.094	49%	0.492	C	S	.	.	H	α-helix	trans	-68.8	-35.9	-177.9	-124.3	97.4	0	0	0	112.4	Y328 F332 W400 L408 K409 I415	Y328-L411 HydrophobicContact CD1-CD2 3.57Å; Y328-L411 HydrophobicContact CD2-CD2 3.62Å; Y328-L411 HydrophobicContact CE1-CD2 3.74Å; Y328-L411 HydrophobicContact CE2-CD2 3.78Å; Y328-L411 HydrophobicContact CG-CD2 3.51Å; F332-L411 HydrophobicContact CB-CD2 4.39Å; W400-L411 HydrophobicContact CZ2-CD1 4.37Å; L408-L411 PolarHBondContact O-N 3.41Å; K409-L411 VanDerWaalsContact C-N 3.34Å; L411-I415 HydrophobicContact CD2-CD1 3.72Å; L411-I415 HydrophobicContact CG-CD1 4.15Å; L411-I415 WeakPolarHBondContact O-CB 3.37Å; L411-I415 WeakPolarHBondContact O-CG1 3.49Å; L411-I415 PolarHBondContact O-N 2.92Å; L411-I415 VanDerWaalsContact O-N 3.12Å
412	H	49.4	Very low	55.5	Low	136 Å²	136	104.9 Å²	104.9	63%	0.63	51%	0.511	S	S	*	.	H	α-helix	trans	-61.8	-50.9	177.8	-121.6	73.2	0	0	0	110.1	I410 Q414 I415 T416	I410-H412 PolarHBondContact O-N 3.19Å; H412-Q414 PolarHBondContact O-N 2.91Å; H412-I415 PolarHBondContact O-N 3.28Å; H412-T416 WeakPolarHBondContact O-CB 3.47Å; H412-T416 PolarHBondContact O-N 3Å; H412-T416 PolarHBondContact O-OG1 3.34Å
413	S	49.4	Very low	53	Low	71 Å²	71	106 Å²	106	50%	0.497	52%	0.519	S	S	.	.	H	α-helix	trans	-67.8	-32.1	-174.5	89.8	0	0	0	0	114.1	I410 R417	I410-S413 PolarHBondContact O-N 2.79Å; S413-R417 WeakPolarHBondContact O-CB 3.41Å; S413-R417 PolarHBondContact O-N 3.37Å; S413-R417 VanDerWaalsContact O-N 3.16Å
414	Q	49.4	Very low	50.2	Low	92 Å²	92	104.8 Å²	104.8	43%	0.43	52%	0.52	S	S	.	.	H	α-helix	trans	-76.4	-36.5	178	-69.6	-169	-12.7	0	0	112.8	I410 H412 R418	I410-Q414 HydrophobicContact CG2-CG 4.42Å; I410-Q414 PolarHBondContact O-N 3.38Å; H412-Q414 PolarHBondContact O-N 2.91Å; Q414-R418 PolarHBondContact O-N 3.41Å
415	I	49.9	Very low	47.4	Very low	52 Å²	52	110.7 Å²	110.7	27%	0.267	55%	0.549	S	S	.	.	H	α-helix	trans	-76.4	-41.3	177.8	-64.9	173.5	0	0	0	110.7	Y328 L411 H412 R417 R418 Q419	Y328-I415 HydrophobicContact CD1-CD1 3.86Å; Y328-I415 HydrophobicContact CG-CD1 4.4Å; L411-I415 HydrophobicContact CD2-CD1 3.72Å; L411-I415 HydrophobicContact CG-CD1 4.15Å; L411-I415 WeakPolarHBondContact O-CB 3.37Å; L411-I415 WeakPolarHBondContact O-CG1 3.49Å; L411-I415 PolarHBondContact O-N 2.92Å; L411-I415 VanDerWaalsContact O-N 3.12Å; H412-I415 PolarHBondContact O-N 3.28Å; I415-R417 VanDerWaalsContact C-N 3.26Å; I415-R417 PolarHBondContact O-N 2.98Å; I415-R418 PolarHBondContact O-N 2.74Å; I415-Q419 PolarHBondContact O-N 3.3Å
416	T	44.2	Very low	44.9	Very low	53 Å²	53	115.9 Å²	115.9	33%	0.325	57%	0.569	S	S	.	*	H	α-helix	trans	-59.8	-40.5	174.3	-44.4	0	0	0	0	110.1	H412 R418 Q419 Y420	H412-T416 WeakPolarHBondContact O-CB 3.47Å; H412-T416 PolarHBondContact O-N 3Å; H412-T416 PolarHBondContact O-OG1 3.34Å; T416-R418 PolarHBondContact O-N 3.27Å; T416-Q419 PolarHBondContact O-N 3.48Å; T416-Y420 HydrophobicContact CG2-CD2 3.85Å; T416-Y420 HydrophobicContact CG2-CE2 3.83Å; T416-Y420 WeakPolarHBondContact O-CD2 3.36Å; T416-Y420 PolarHBondContact O-N 3.18Å; T416-Y420 VanDerWaalsContact O-N 3.09Å
417	R	39.8	Very low	42.8	Very low	180 Å²	180	118.2 Å²	118.2	68%	0.679	57%	0.573	S	S	*	*	H	α-helix	trans	-57.6	-44.4	171.3	-87.9	-176.9	177.3	-179.3	-0.4	112.4	S413 I415 Y420 F421	S413-R417 WeakPolarHBondContact O-CB 3.41Å; S413-R417 PolarHBondContact O-N 3.37Å; S413-R417 VanDerWaalsContact O-N 3.16Å; I415-R417 VanDerWaalsContact C-N 3.26Å; I415-R417 PolarHBondContact O-N 2.98Å; R417-Y420 PolarHBondContact O-N 3.42Å; R417-F421 HydrophobicContact CB-CD2 4.39Å; R417-F421 WeakPolarHBondContact O-CB 3.41Å; R417-F421 WeakPolarHBondContact O-CD2 3.47Å; R417-F421 PolarHBondContact O-N 3.16Å
418	R	38.9	Very low	41.2	Very low	116 Å²	116	118.5 Å²	118.5	44%	0.438	58%	0.582	S	S	.	*	H	α-helix	trans	-68.5	-35.9	178.7	-84	-174.4	175.9	153.8	4.5	114	R334 D335 Q414 I415 T416 Y420 G422	R334-R418 VanDerWaalsContact NH2-NH1 3.17Å; D335-R418 IonicContact OD1-CZ 3.83Å; D335-R418 IonicContact OD1-NH1 2.93Å; D335-R418 PolarHBondContact OD1-NH1 3.06Å; D335-R418 VanDerWaalsContact OD1-NH1 3.11Å; D335-R418 IonicContact OD1-NH2 3.44Å; D335-R418 PolarHBondContact OD1-NH2 3.44Å; D335-R418 IonicContact OD2-CZ 3.45Å; D335-R418 IonicContact OD2-NH1 3.75Å; D335-R418 PolarHBondContact OD2-NH1 3.41Å; D335-R418 IonicContact OD2-NH2 2.88Å; Q414-R418 PolarHBondContact O-N 3.41Å; I415-R418 PolarHBondContact O-N 2.74Å; T416-R418 PolarHBondContact O-N 3.27Å; R418-Y420 VanDerWaalsContact C-N 3.33Å; R418-G422 PolarHBondContact O-N 3.39Å
419	Q	42.6	Very low	39.9	Very low	140 Å²	140	118.5 Å²	118.5	65%	0.654	60%	0.596	S	S	*	*	H	α-helix	trans	-66.1	-36	175.3	-78.5	-178.2	-28.7	0	0	112	I415 T416	I415-Q419 PolarHBondContact O-N 3.3Å; T416-Q419 PolarHBondContact O-N 3.48Å
420	Y	35.6	Very low	38.9	Very low	162 Å²	162	114.7 Å²	114.7	64%	0.635	59%	0.592	S	S	*	*	H	α-helix	trans	-76.1	-39.7	175.7	-84.9	-88.7	0	0	0	113.1	T416 R417 R418 G422 V423 I424	T416-Y420 HydrophobicContact CG2-CD2 3.85Å; T416-Y420 HydrophobicContact CG2-CE2 3.83Å; T416-Y420 WeakPolarHBondContact O-CD2 3.36Å; T416-Y420 PolarHBondContact O-N 3.18Å; T416-Y420 VanDerWaalsContact O-N 3.09Å; R417-Y420 PolarHBondContact O-N 3.42Å; R418-Y420 VanDerWaalsContact C-N 3.33Å; Y420-G422 VanDerWaalsContact C-N 3.31Å; Y420-G422 PolarHBondContact O-N 3.23Å; Y420-V423 PolarHBondContact O-N 3.25Å; Y420-I424 PolarHBondContact O-N 2.64Å
421	F	35.9	Very low	37.8	Very low	145 Å²	145	116.2 Å²	116.2	64%	0.636	61%	0.609	S	S	*	*	H	α-helix	trans	-74.1	-17.7	178.7	-82.3	-70.9	0	0	0	114.1	R417 V423	R417-F421 HydrophobicContact CB-CD2 4.39Å; R417-F421 WeakPolarHBondContact O-CB 3.41Å; R417-F421 WeakPolarHBondContact O-CD2 3.47Å; R417-F421 PolarHBondContact O-N 3.16Å; F421-V423 PolarHBondContact O-N 3.16Å
422	G	35.7	Very low	37	Very low	67 Å²	67	123.7 Å²	123.7	69%	0.691	65%	0.647	S	S	*	*	T	Hydrogen-bonded Turn	trans	-71.9	-14	172.5	0	0	0	0	0	114.7	R418 Y420	R418-G422 PolarHBondContact O-N 3.39Å; Y420-G422 VanDerWaalsContact C-N 3.31Å; Y420-G422 PolarHBondContact O-N 3.23Å
423	V	37.8	Very low	36	Very low	126 Å²	126	120.3 Å²	120.3	76%	0.764	65%	0.649	S	S	*	*	T	Hydrogen-bonded Turn	trans	-112.3	-13.3	-178.4	-179.8	0	0	0	0	112.4	Y420 F421	Y420-V423 PolarHBondContact O-N 3.25Å; F421-V423 PolarHBondContact O-N 3.16Å
424	I	30.5	Very low	35	Very low	91 Å²	91	123.5 Å²	123.5	47%	0.467	67%	0.666	S	S	.	*			trans	-120	68.4	-176.1	-52.9	167.8	0	0	0	109.1	Y420 N426	Y420-I424 PolarHBondContact O-N 2.64Å; I424-N426 PolarHBondContact O-N 3.18Å
425	H	29.2	Very low	34	Very low	179 Å²	179	125.7 Å²	125.7	83%	0.829	68%	0.679	S	S	*	*	S	Bend	trans	-85.6	81.6	148.3	-104.1	-75	0	0	0	106.6
426	N	29.8	Very low	33	Very low	141 Å²	141	131.9 Å²	131.9	75%	0.754	70%	0.701	S	S	*	*	S	Bend	trans	152.9	86	162	-83.2	-14.6	0	0	0	106.6	I424	I424-N426 PolarHBondContact O-N 3.18Å
427	F	30.4	Very low	32.3	Very low	199 Å²	199	138.6 Å²	138.6	87%	0.873	73%	0.731	S	S	*	*			trans	-178.4	128.7	135.6	-104.7	-75.1	0	0	0	108.6
428	D	28.8	Very low	31.9	Very low	160 Å²	160	138.8 Å²	138.8	86%	0.856	74%	0.737	S	S	*	*			trans	-62.3	159.8	-170.6	-73.8	-57.7	0	0	0	115.3	C430	D428-C430 PolarHBondContact O-N 3.27Å
429	A	30.4	Very low	31.5	Very low	95 Å²	95	138.3 Å²	138.3	79%	0.785	75%	0.751	S	S	*	*			trans	-46.3	124	174.2	0	0	0	0	0	114.5
430	C	27.3	Very low	30.9	Very low	117 Å²	117	136.4 Å²	136.4	79%	0.791	76%	0.759	S	S	*	*			trans	-167.4	128.5	138.2	-109.7	0	0	0	0	112.1	D428	D428-C430 PolarHBondContact O-N 3.27Å
431	S	29.1	Very low	30.6	Very low	101 Å²	101	133.7 Å²	133.7	71%	0.706	76%	0.764	S	S	*	*			trans	68.7	113	142.3	-46.2	0	0	0	0	119.3
432	I	32.5	Very low	30.4	Very low	174 Å²	174	132.7 Å²	132.7	89%	0.892	77%	0.77	S	S	*	*			trans	-172.3	110.2	137.9	-81.1	134.5	0	0	0	103.8
433	G	28.2	Very low	30.1	Very low	65 Å²	65	140.7 Å²	140.7	67%	0.67	78%	0.779	S	S	*	*			cis	95.2	73.1	36.8	0	0	0	0	0	109.2
434	T	28.6	Very low	29.6	Very low	138 Å²	138	146.8 Å²	146.8	85%	0.847	79%	0.789	S	S	*	*			trans	-16.1	131.5	164.4	-46.5	0	0	0	0	115.5
435	I	27.9	Very low	30.3	Very low	138 Å²	138	152.2 Å²	152.2	71%	0.708	83%	0.827	S	S	*	*			trans	-164.3	131.8	154.5	-107.4	150.4	0	0	0	113.4
436	Y	29.7	Very low	30.4	Very low	183 Å²	183	150.9 Å²	150.9	72%	0.718	83%	0.826	S	S	*	*			trans	69.2	83.5	162.7	-60.5	-55.9	0	0	0	121.4	F438	Y436-F438 PolarHBondContact O-N 3.4Å
437	M	29.1	Very low	30.4	Very low	193 Å²	193	151.4 Å²	151.4	95%	0.951	83%	0.83	S	S	*	*			trans	-63.5	104.6	138.2	-90.7	177.3	166.8	0	0	108.9	S439	M437-S439 PolarHBondContact O-N 3.48Å
438	F	31.1	Very low	30.4	Very low	185 Å²	185	148.8 Å²	148.8	81%	0.811	83%	0.828	S	S	*	*			trans	-72.9	116.1	163.8	-96.5	-89.8	0	0	0	109	Y436 A440	Y436-F438 PolarHBondContact O-N 3.4Å; F438-A440 PolarHBondContact O-N 3.4Å
439	S	32.3	Very low	30.5	Very low	106 Å²	106	148.1 Å²	148.1	74%	0.741	83%	0.826	S	S	*	*			trans	-51	115.3	174.4	50.7	0	0	0	0	112.1	M437	M437-S439 PolarHBondContact O-N 3.48Å
440	A	28.1	Very low	30.5	Very low	99 Å²	99	151.4 Å²	151.4	82%	0.818	83%	0.829	S	S	*	*			trans	-99.7	98	161.9	0	0	0	0	0	107.7	F438	F438-A440 PolarHBondContact O-N 3.4Å
441	S	30.8	Very low	30.7	Very low	105 Å²	105	153.7 Å²	153.7	73%	0.734	83%	0.831	S	S	*	*			trans	-176.5	67.7	164.1	57.6	0	0	0	0	112.1
442	T	31.3	Very low	30.9	Very low	124 Å²	124	157.5 Å²	157.5	76%	0.761	84%	0.84	S	S	*	*			trans	-149.9	56.2	165.8	46.2	0	0	0	0	112.1
443	W	30.1	Very low	30.7	Very low	236 Å²	236	156.2 Å²	156.2	89%	0.894	84%	0.836	S	S	*	*			trans	-150.7	63.4	160.9	-74.1	93.4	0	0	0	109.8
444	W	26.4	Very low	30.9	Very low	254 Å²	254	163.8 Å²	163.8	96%	0.962	85%	0.85	S	S	*	*			trans	-149.5	73.9	164.1	-79.2	99.7	0	0	0	109.3
445	T	45.9	Very low	31.2	Very low	205 Å²	205	166.2 Å²	166.2	100%	1.258	85%	0.851	S	S	*	*			trans	-173.8	0	150.1	46.1	0	0	0	0	104.7

Retrieved 445 of 445 residues in 130.4 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).