A0A5K4FA48_SCHMA Loading...

G_PROTEIN_RECEP_F1_2 domain-containing protein

AlphaFold DB , UniProt , Accession A0A5K4FA48, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 441 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	36.5	Very low	39.4	Very low	186 Å²	186	124.8 Å²	124.8	92%	0.916	68%	0.678	S	S	*	*				0	105.3	0	-85.2	175.1	169.2	0	0	108.8	Y3	M1-Y3 VanDerWaalsContact C-N 3.3Å; M1-Y3 HydrophobicContact CB-CD2 3.98Å; M1-Y3 HydrophobicContact CB-CE2 4.06Å; M1-Y3 HydrophobicContact CG-CE2 4.38Å; M1-Y3 PolarHBondContact O-N 3.09Å; M1-Y3 HydrophobicContact SD-CE2 3.83Å
2	C	30.7	Very low	40.9	Very low	66 Å²	66	124.3 Å²	124.3	45%	0.446	67%	0.674	S	S	.	*			trans	-74.9	85.1	171.5	-52.7	0	0	0	0	108	S4 C390	C2-S4 PolarHBondContact O-N 3.16Å; C2-C390 HydrophobicContact CB-CB 3.87Å; C2-C390 WeakPolarHBondContact CB-SG 3.25Å; C2-C390 WeakPolarHBondContact SG-CB 3.35Å; C2-C390 CovalentContact SG-SG 2.03Å; C2-C390 PolarHBondContact SG-SG 3.41Å
3	Y	30.8	Very low	42.5	Very low	197 Å²	197	118.4 Å²	118.4	77%	0.773	64%	0.642	S	S	*	*			trans	-79.6	96.7	162.8	-84.1	-81.8	0	0	0	106.9	M1 T5	M1-Y3 VanDerWaalsContact C-N 3.3Å; M1-Y3 HydrophobicContact CB-CD2 3.98Å; M1-Y3 HydrophobicContact CB-CE2 4.06Å; M1-Y3 HydrophobicContact CG-CE2 4.38Å; M1-Y3 PolarHBondContact O-N 3.09Å; M1-Y3 HydrophobicContact SD-CE2 3.83Å; Y3-T5 PolarHBondContact O-N 3.09Å
4	S	35.5	Very low	44.2	Very low	67 Å²	67	116.3 Å²	116.3	47%	0.469	63%	0.63	S	S	.	*			trans	-69	111.9	165.8	-60	0	0	0	0	107.7	C2 T6	C2-S4 PolarHBondContact O-N 3.16Å; S4-T6 PolarHBondContact O-N 3.43Å; S4-T6 VanDerWaalsContact O-N 3.15Å
5	T	30.8	Very low	45.8	Very low	142 Å²	142	112.9 Å²	112.9	87%	0.871	62%	0.619	S	S	*	*			trans	-62.5	103.9	160.6	39.2	0	0	0	0	108.4	Y3	Y3-T5 PolarHBondContact O-N 3.09Å
6	T	37.2	Very low	47.4	Very low	72 Å²	72	110.6 Å²	110.6	44%	0.442	61%	0.605	S	S	.	*			trans	-131.6	106.8	165	30.4	0	0	0	0	110.5	S4 N8	S4-T6 PolarHBondContact O-N 3.43Å; S4-T6 VanDerWaalsContact O-N 3.15Å; T6-N8 PolarHBondContact O-N 3.37Å
7	T	38.3	Very low	49.2	Very low	137 Å²	137	107.8 Å²	107.8	84%	0.84	59%	0.589	S	S	*	*			trans	-44.2	122.9	150.6	40.4	0	0	0	0	111.7	N9	T7-N9 PolarHBondContact O-N 3.07Å
8	N	38.3	Very low	51	Low	146 Å²	146	109.2 Å²	109.2	78%	0.781	59%	0.591	S	S	*	*	S	Bend	trans	41.5	72.1	148.9	-109.2	0	0	0	0	117.9	T6	T6-N8 PolarHBondContact O-N 3.37Å
9	N	46.1	Very low	52.9	Low	123 Å²	123	108.4 Å²	108.4	66%	0.658	59%	0.585	S	S	*	*			trans	-166	67.7	150.3	-116.4	-8.2	0	0	0	108.9	T7 N11 N13	T7-N9 PolarHBondContact O-N 3.07Å; N9-N11 PolarHBondContact O-N 3.27Å; N9-N13 PolarHBondContact O-ND2 3.16Å
10	N	54.3	Low	54.5	Low	94 Å²	94	104.4 Å²	104.4	50%	0.503	56%	0.562	S	S	.	*	H	α-helix	trans	-74.4	-24.8	-152.5	-70.5	-2.1	0	0	0	116.1
11	N	54.9	Low	55.9	Low	143 Å²	143	107.1 Å²	107.1	77%	0.765	57%	0.565	S	S	*	*	H	α-helix	trans	-84.4	-28.1	-173.7	-67.1	-3.1	0	0	0	114.2	N9	N9-N11 PolarHBondContact O-N 3.27Å
12	N	57.8	Low	58.4	Low	118 Å²	118	104.9 Å²	104.9	63%	0.631	55%	0.55	S	S	*	*	H	α-helix	trans	-87.4	-29.1	-179.2	-77.1	-7.6	0	0	0	112.8	S15 I16	N12-S15 PolarHBondContact O-OG 3.42Å; N12-I16 WeakPolarHBondContact O-CG1 3.37Å; N12-I16 PolarHBondContact O-N 2.7Å
13	N	61.2	Low	61.2	Low	48 Å²	48	104.1 Å²	104.1	26%	0.257	54%	0.541	S	S	.	.	H	α-helix	trans	-73.5	-35.1	179.7	-72.7	-19.8	0	0	0	111.9	N9 I16 N17	N9-N13 PolarHBondContact O-ND2 3.16Å; N13-I16 PolarHBondContact O-N 3.46Å; N13-N17 WeakPolarHBondContact O-CB 3.4Å; N13-N17 PolarHBondContact O-N 2.95Å; N13-N17 PolarHBondContact O-ND2 3.08Å; N13-N17 VanDerWaalsContact O-ND2 3.13Å
14	D	65.9	Low	63.9	Low	89 Å²	89	95.8 Å²	95.8	48%	0.476	51%	0.509	S	S	.	.	H	α-helix	trans	-67.3	-41.8	178.8	-72.1	-12.6	0	0	0	111.8	I16 N17 H18	D14-I16 PolarHBondContact O-N 3.01Å; D14-N17 PolarHBondContact O-N 3.41Å; D14-H18 PolarHBondContact O-CD2 3.47Å; D14-H18 PolarHBondContact O-N 3.39Å
15	S	68.3	Low	66.4	Low	66 Å²	66	95.5 Å²	95.5	46%	0.462	50%	0.502	S	S	.	.	H	α-helix	trans	-64.1	-40.2	177.8	66.1	0	0	0	0	112.6	N12 H18 L19	N12-S15 PolarHBondContact O-OG 3.42Å; S15-H18 PolarHBondContact O-N 3.44Å; S15-L19 WeakPolarHBondContact O-CB 3.39Å; S15-L19 PolarHBondContact O-N 2.94Å
16	I	72.6	Confident	69.4	Low	76 Å²	76	94.4 Å²	94.4	39%	0.39	49%	0.485	S	S	.	.	H	α-helix	trans	-64	-44.1	175.3	-66.9	170	0	0	0	110.6	N12 N13 D14 H18 L19 Q20	N12-I16 WeakPolarHBondContact O-CG1 3.37Å; N12-I16 PolarHBondContact O-N 2.7Å; N13-I16 PolarHBondContact O-N 3.46Å; D14-I16 PolarHBondContact O-N 3.01Å; I16-H18 VanDerWaalsContact C-N 3.34Å; I16-H18 PolarHBondContact O-N 3.3Å; I16-L19 PolarHBondContact O-N 3.41Å; I16-Q20 HydrophobicContact CG2-CG 4.42Å; I16-Q20 WeakPolarHBondContact O-CB 3.3Å; I16-Q20 WeakPolarHBondContact O-CG 3.36Å; I16-Q20 PolarHBondContact O-N 2.87Å
17	N	77.5	Confident	72	Confident	62 Å²	62	91.2 Å²	91.2	33%	0.332	47%	0.465	S	S	.	.	H	α-helix	trans	-63.6	-39.9	177.9	-69.5	-24.7	0	0	0	111.8	N13 D14 R21	N13-N17 WeakPolarHBondContact O-CB 3.4Å; N13-N17 PolarHBondContact O-N 2.95Å; N13-N17 PolarHBondContact O-ND2 3.08Å; N13-N17 VanDerWaalsContact O-ND2 3.13Å; D14-N17 PolarHBondContact O-N 3.41Å; N17-R21 WeakPolarHBondContact O-CB 3.34Å; N17-R21 PolarHBondContact O-N 3.41Å
18	H	82	Confident	74.5	Confident	134 Å²	134	84.7 Å²	84.7	62%	0.62	43%	0.425	S	S	*	.	H	α-helix	trans	-64.9	-44.2	175.1	-81.5	-67.9	0	0	0	112.3	D14 S15 I16 R21 F22	D14-H18 PolarHBondContact O-CD2 3.47Å; D14-H18 PolarHBondContact O-N 3.39Å; S15-H18 PolarHBondContact O-N 3.44Å; I16-H18 VanDerWaalsContact C-N 3.34Å; I16-H18 PolarHBondContact O-N 3.3Å; H18-R21 PolarHBondContact O-N 3.44Å; H18-F22 WeakPolarHBondContact O-CB 3.34Å; H18-F22 PolarHBondContact O-N 2.92Å
19	L	86.3	Confident	77.2	Confident	93 Å²	93	83.6 Å²	83.6	49%	0.487	41%	0.414	S	S	.	.	H	α-helix	trans	-63.7	-45.6	177.1	-179.6	65.1	0	0	0	111.7	S15 I16 R21 F22 I23 W392	S15-L19 WeakPolarHBondContact O-CB 3.39Å; S15-L19 PolarHBondContact O-N 2.94Å; I16-L19 PolarHBondContact O-N 3.41Å; L19-R21 VanDerWaalsContact C-N 3.33Å; L19-R21 PolarHBondContact O-N 3.37Å; L19-F22 PolarHBondContact O-N 2.84Å; L19-I23 HydrophobicContact CD1-CD1 4.07Å; L19-I23 HydrophobicContact CD1-CG1 4.41Å; L19-I23 HydrophobicContact CG-CD1 3.89Å; L19-I23 WeakPolarHBondContact O-CG1 3.35Å; L19-I23 PolarHBondContact O-N 2.85Å; L19-W392 HydrophobicContact CD2-CH2 4.45Å
20	Q	84.2	Confident	79.5	Confident	28 Å²	28	79.6 Å²	79.6	13%	0.131	39%	0.392	C	S	.	.	H	α-helix	trans	-57.1	-47.2	175.4	-78.7	178.8	-24.1	0	0	111.3	I16 F22 I23 Q24 W392 I395	I16-Q20 HydrophobicContact CG2-CG 4.42Å; I16-Q20 WeakPolarHBondContact O-CB 3.3Å; I16-Q20 WeakPolarHBondContact O-CG 3.36Å; I16-Q20 PolarHBondContact O-N 2.87Å; Q20-F22 VanDerWaalsContact C-N 3.34Å; Q20-F22 PolarHBondContact O-N 3.5Å; Q20-I23 PolarHBondContact O-N 3.38Å; Q20-Q24 WeakPolarHBondContact O-CB 3.46Å; Q20-Q24 PolarHBondContact O-N 2.85Å; Q20-W392 HydrophobicContact CG-CD2 4Å; Q20-W392 VanDerWaalsContact CG-CE2 3.48Å; Q20-W392 HydrophobicContact CG-CE3 4.35Å; Q20-W392 HydrophobicContact CG-CH2 3.81Å; Q20-W392 HydrophobicContact CG-CZ2 3.37Å; Q20-W392 HydrophobicContact CG-CZ3 4.27Å; Q20-W392 VanDerWaalsContact NE2-CE2 3.34Å; Q20-I395 HydrophobicContact CB-CD1 4.07Å; Q20-I395 HydrophobicContact CG-CD1 4.22Å
21	R	84.5	Confident	81.3	Confident	162 Å²	162	75.1 Å²	75.1	61%	0.611	37%	0.368	S	S	*	.	H	α-helix	trans	-62.8	-40.4	178	-172.6	175	179.4	-175.4	-1	112.1	N17 H18 L19 Q24 I25	N17-R21 WeakPolarHBondContact O-CB 3.34Å; N17-R21 PolarHBondContact O-N 3.41Å; H18-R21 PolarHBondContact O-N 3.44Å; L19-R21 VanDerWaalsContact C-N 3.33Å; L19-R21 PolarHBondContact O-N 3.37Å; R21-Q24 PolarHBondContact O-N 2.92Å; R21-I25 HydrophobicContact CG-CD1 4.12Å; R21-I25 VanDerWaalsContact O-CG1 3.3Å; R21-I25 WeakPolarHBondContact O-CG1 3.45Å; R21-I25 PolarHBondContact O-N 2.87Å
22	F	88.7	Confident	83.2	Confident	140 Å²	140	71 Å²	71	61%	0.614	35%	0.346	S	S	*	.	H	α-helix	trans	-62.3	-48.2	176.1	-180	-95.8	0	0	0	111.8	H18 L19 Q20 Q24 I25 F26	H18-F22 WeakPolarHBondContact O-CB 3.34Å; H18-F22 PolarHBondContact O-N 2.92Å; L19-F22 PolarHBondContact O-N 2.84Å; Q20-F22 VanDerWaalsContact C-N 3.34Å; Q20-F22 PolarHBondContact O-N 3.5Å; F22-Q24 VanDerWaalsContact C-N 3.33Å; F22-Q24 PolarHBondContact O-N 3.46Å; F22-I25 PolarHBondContact O-N 3.31Å; F22-F26 WeakPolarHBondContact O-CB 3.44Å; F22-F26 PolarHBondContact O-N 3.48Å
23	I	90	Very high	85	Confident	50 Å²	50	70.9 Å²	70.9	26%	0.256	34%	0.344	S	S	.	.	H	α-helix	trans	-61.6	-43.5	177.2	-69.8	165.7	0	0	0	110.7	L19 Q20 I25 F26 I27 W392 I395	L19-I23 HydrophobicContact CD1-CD1 4.07Å; L19-I23 HydrophobicContact CD1-CG1 4.41Å; L19-I23 HydrophobicContact CG-CD1 3.89Å; L19-I23 WeakPolarHBondContact O-CG1 3.35Å; L19-I23 PolarHBondContact O-N 2.85Å; Q20-I23 PolarHBondContact O-N 3.38Å; I23-I25 PolarHBondContact O-N 3.05Å; I23-F26 WeakPolarHBondContact O-CB 3.25Å; I23-F26 PolarHBondContact O-N 2.98Å; I23-I27 HydrophobicContact CG2-CD1 3.79Å; I23-I27 HydrophobicContact CG2-CG1 4.44Å; I23-I27 VanDerWaalsContact O-CG1 3.27Å; I23-I27 WeakPolarHBondContact O-CG1 3.41Å; I23-I27 PolarHBondContact O-N 3.26Å; I23-W392 HydrophobicContact CD1-CH2 3.51Å; I23-W392 HydrophobicContact CD1-CZ3 3.61Å; I23-I395 HydrophobicContact CG2-CG2 3.95Å
24	Q	87.5	Confident	86.6	Confident	22 Å²	22	68.6 Å²	68.6	10%	0.103	33%	0.332	C	S	.	.	H	α-helix	trans	-58.5	-45.7	176.6	161.2	176.7	15.1	0	0	111.8	Q20 R21 F22 I27 G28 L191 S192 N389	Q20-Q24 WeakPolarHBondContact O-CB 3.46Å; Q20-Q24 PolarHBondContact O-N 2.85Å; R21-Q24 PolarHBondContact O-N 2.92Å; F22-Q24 VanDerWaalsContact C-N 3.33Å; F22-Q24 PolarHBondContact O-N 3.46Å; Q24-I27 PolarHBondContact O-N 3.21Å; Q24-G28 PolarHBondContact O-N 3.17Å; Q24-G28 VanDerWaalsContact O-N 3.1Å; Q24-L191 PolarHBondContact NE2-O 2.89Å; Q24-S192 WeakPolarHBondContact CG-O 3.34Å; Q24-S192 PolarHBondContact NE2-O 3.46Å; Q24-N389 WeakPolarHBondContact CG-ND2 3.49Å; Q24-N389 PolarHBondContact NE2-ND2 3.39Å
25	I	89	Confident	88	Confident	60 Å²	60	67.3 Å²	67.3	31%	0.308	32%	0.322	S	S	.	.	H	α-helix	trans	-64.5	-42.1	176.3	-70.9	167.1	0	0	0	110.6	R21 F22 I23 I27 G28 F29	R21-I25 HydrophobicContact CG-CD1 4.12Å; R21-I25 VanDerWaalsContact O-CG1 3.3Å; R21-I25 WeakPolarHBondContact O-CG1 3.45Å; R21-I25 PolarHBondContact O-N 2.87Å; F22-I25 PolarHBondContact O-N 3.31Å; I23-I25 PolarHBondContact O-N 3.05Å; I25-I27 VanDerWaalsContact C-N 3.33Å; I25-I27 PolarHBondContact O-N 3.07Å; I25-G28 WeakPolarHBondContact O-CA 3.45Å; I25-G28 PolarHBondContact O-N 3.24Å; I25-G28 VanDerWaalsContact O-N 3.08Å; I25-F29 HydrophobicContact CG2-CD2 3.84Å; I25-F29 HydrophobicContact CG2-CE2 3.46Å; I25-F29 VanDerWaalsContact CG2-CE2 3.46Å; I25-F29 VanDerWaalsContact O-CD2 3.28Å; I25-F29 WeakPolarHBondContact O-CD2 3.36Å; I25-F29 PolarHBondContact O-N 2.82Å
26	F	93.1	Very high	89.3	Confident	120 Å²	120	68.1 Å²	68.1	53%	0.526	32%	0.321	S	S	.	.	H	α-helix	trans	-59.9	-42.2	176.9	-175.9	-101.5	0	0	0	112.3	F22 I23 G28 F29 I30	F22-F26 WeakPolarHBondContact O-CB 3.44Å; F22-F26 PolarHBondContact O-N 3.48Å; I23-F26 WeakPolarHBondContact O-CB 3.25Å; I23-F26 PolarHBondContact O-N 2.98Å; F26-G28 VanDerWaalsContact C-N 3.3Å; F26-G28 PolarHBondContact O-N 3.24Å; F26-F29 WeakPolarHBondContact O-CB 3.46Å; F26-F29 PolarHBondContact O-N 2.99Å; F26-F29 VanDerWaalsContact O-N 3.15Å; F26-I30 HydrophobicContact CD1-CD1 3.99Å; F26-I30 HydrophobicContact CE1-CD1 3.7Å; F26-I30 HydrophobicContact CE1-CG1 4.31Å; F26-I30 HydrophobicContact CZ-CD1 4.47Å; F26-I30 PolarHBondContact O-N 3.09Å; F26-I30 VanDerWaalsContact O-N 3.1Å
27	I	91.5	Very high	90.3	Very high	5 Å²	5	65.1 Å²	65.1	3%	0.026	31%	0.308	C	S	.	.	H	α-helix	trans	-60	-41.6	173	-69.7	162.5	0	0	0	110.9	I23 Q24 I25 F29 I30 G31 I395 L399 I402	I23-I27 HydrophobicContact CG2-CD1 3.79Å; I23-I27 HydrophobicContact CG2-CG1 4.44Å; I23-I27 VanDerWaalsContact O-CG1 3.27Å; I23-I27 WeakPolarHBondContact O-CG1 3.41Å; I23-I27 PolarHBondContact O-N 3.26Å; Q24-I27 PolarHBondContact O-N 3.21Å; I25-I27 VanDerWaalsContact C-N 3.33Å; I25-I27 PolarHBondContact O-N 3.07Å; I27-F29 VanDerWaalsContact C-N 3.32Å; I27-F29 PolarHBondContact O-N 3.25Å; I27-I30 WeakPolarHBondContact O-CB 3.13Å; I27-I30 PolarHBondContact O-N 3.37Å; I27-G31 PolarHBondContact O-N 2.94Å; I27-I395 HydrophobicContact CD1-CG2 3.39Å; I27-L399 HydrophobicContact CD1-CB 3.99Å; I27-L399 HydrophobicContact CG1-CB 4.29Å; I27-L399 HydrophobicContact CG1-CD1 4.1Å; I27-L399 HydrophobicContact CG2-CB 4.5Å; I27-I402 HydrophobicContact CG2-CD1 3.36Å
28	G	91.2	Very high	91.1	Very high	0 Å²	0	62.1 Å²	62.1	0%	0	29%	0.292	C	S	.	.	H	α-helix	trans	-57.7	-41.7	173.6	0	0	0	0	0	112.9	Q24 I25 F26 G31 I32	Q24-G28 PolarHBondContact O-N 3.17Å; Q24-G28 VanDerWaalsContact O-N 3.1Å; I25-G28 WeakPolarHBondContact O-CA 3.45Å; I25-G28 PolarHBondContact O-N 3.24Å; I25-G28 VanDerWaalsContact O-N 3.08Å; F26-G28 VanDerWaalsContact C-N 3.3Å; F26-G28 PolarHBondContact O-N 3.24Å; G28-G31 WeakPolarHBondContact O-CA 3.42Å; G28-G31 PolarHBondContact O-N 3.48Å; G28-G31 VanDerWaalsContact O-N 3.16Å; G28-I32 WeakPolarHBondContact O-CG1 3.49Å; G28-I32 PolarHBondContact O-N 3.01Å
29	F	94.1	Very high	91.7	Very high	123 Å²	123	61 Å²	61	54%	0.539	29%	0.286	S	S	.	.	H	α-helix	trans	-64.5	-39.3	175.2	-77.5	-67.3	0	0	0	113.1	I25 F26 I27 G31 I32 L33	I25-F29 HydrophobicContact CG2-CD2 3.84Å; I25-F29 HydrophobicContact CG2-CE2 3.46Å; I25-F29 VanDerWaalsContact CG2-CE2 3.46Å; I25-F29 VanDerWaalsContact O-CD2 3.28Å; I25-F29 WeakPolarHBondContact O-CD2 3.36Å; I25-F29 PolarHBondContact O-N 2.82Å; F26-F29 WeakPolarHBondContact O-CB 3.46Å; F26-F29 PolarHBondContact O-N 2.99Å; F26-F29 VanDerWaalsContact O-N 3.15Å; I27-F29 VanDerWaalsContact C-N 3.32Å; I27-F29 PolarHBondContact O-N 3.25Å; F29-G31 VanDerWaalsContact C-N 3.26Å; F29-G31 PolarHBondContact O-N 3.14Å; F29-I32 HydrophobicContact CD1-CD1 4.25Å; F29-I32 PolarHBondContact O-N 3.38Å; F29-L33 WeakPolarHBondContact O-CG 3.46Å; F29-L33 PolarHBondContact O-N 2.88Å
30	I	94.3	Very high	92.1	Very high	39 Å²	39	60.2 Å²	60.2	20%	0.2	28%	0.281	C	S	.	.	H	α-helix	trans	-59.5	-42.6	172	-62.9	169.7	0	0	0	110	F26 I27 L33 S34 I402	F26-I30 HydrophobicContact CD1-CD1 3.99Å; F26-I30 HydrophobicContact CE1-CD1 3.7Å; F26-I30 HydrophobicContact CE1-CG1 4.31Å; F26-I30 HydrophobicContact CZ-CD1 4.47Å; F26-I30 PolarHBondContact O-N 3.09Å; F26-I30 VanDerWaalsContact O-N 3.1Å; I27-I30 WeakPolarHBondContact O-CB 3.13Å; I27-I30 PolarHBondContact O-N 3.37Å; I30-L33 PolarHBondContact O-N 3.41Å; I30-S34 PolarHBondContact O-N 3.31Å; I30-I402 HydrophobicContact CB-CG2 4.31Å; I30-I402 HydrophobicContact CG2-CG2 3.82Å
31	G	93.4	Very high	92.5	Very high	0 Å²	0	58.9 Å²	58.9	0%	0	28%	0.275	C	S	.	.	H	α-helix	trans	-59.1	-46.3	174.9	0	0	0	0	0	112.6	I27 G28 F29 L33 S34 F35 I189	I27-G31 PolarHBondContact O-N 2.94Å; G28-G31 WeakPolarHBondContact O-CA 3.42Å; G28-G31 PolarHBondContact O-N 3.48Å; G28-G31 VanDerWaalsContact O-N 3.16Å; F29-G31 VanDerWaalsContact C-N 3.26Å; F29-G31 PolarHBondContact O-N 3.14Å; G31-L33 VanDerWaalsContact C-N 3.33Å; G31-L33 PolarHBondContact O-N 2.66Å; G31-S34 WeakPolarHBondContact O-CB 3.41Å; G31-S34 PolarHBondContact O-N 2.7Å; G31-S34 VanDerWaalsContact O-N 3.17Å; G31-F35 PolarHBondContact O-N 2.85Å; G31-I189 VanDerWaalsContact C-CD1 3.42Å; G31-I189 WeakPolarHBondContact O-CD1 3.3Å
32	I	94.8	Very high	92.9	Very high	57 Å²	57	53.4 Å²	53.4	29%	0.292	26%	0.256	S	S	.	.	H	α-helix	trans	-59	-44.6	176.2	-67.8	167	0	0	0	111.1	G28 F29 S34 F35 I36 I189 I193	G28-I32 WeakPolarHBondContact O-CG1 3.49Å; G28-I32 PolarHBondContact O-N 3.01Å; F29-I32 HydrophobicContact CD1-CD1 4.25Å; F29-I32 PolarHBondContact O-N 3.38Å; I32-S34 VanDerWaalsContact C-N 3.33Å; I32-S34 PolarHBondContact O-N 3.26Å; I32-F35 WeakPolarHBondContact O-CB 3.44Å; I32-F35 PolarHBondContact O-N 2.9Å; I32-I36 HydrophobicContact CG2-CD1 3.84Å; I32-I36 HydrophobicContact CG2-CG1 4.46Å; I32-I36 WeakPolarHBondContact O-CG1 3.31Å; I32-I36 PolarHBondContact O-N 3.18Å; I32-I189 HydrophobicContact CD1-CG2 4.36Å; I32-I189 HydrophobicContact CG1-CD1 4.33Å; I32-I189 HydrophobicContact CG1-CG2 3.78Å; I32-I193 HydrophobicContact CD1-CD1 4.08Å
33	L	95.5	Very high	93.1	Very high	115 Å²	115	50.2 Å²	50.2	60%	0.602	24%	0.244	S	C	*	.	H	α-helix	trans	-61.7	-41.5	176.7	-70.5	172.9	0	0	0	111.7	F29 I30 G31 G37	F29-L33 WeakPolarHBondContact O-CG 3.46Å; F29-L33 PolarHBondContact O-N 2.88Å; I30-L33 PolarHBondContact O-N 3.41Å; G31-L33 VanDerWaalsContact C-N 3.33Å; G31-L33 PolarHBondContact O-N 2.66Å; L33-G37 PolarHBondContact O-N 3.23Å
34	S	94.3	Very high	93.1	Very high	0 Å²	0	49 Å²	49	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-63.3	-42.2	174.3	-179.7	0	0	0	0	111.9	I30 G31 I32 G37 H38 F406 T409	I30-S34 PolarHBondContact O-N 3.31Å; G31-S34 WeakPolarHBondContact O-CB 3.41Å; G31-S34 PolarHBondContact O-N 2.7Å; G31-S34 VanDerWaalsContact O-N 3.17Å; I32-S34 VanDerWaalsContact C-N 3.33Å; I32-S34 PolarHBondContact O-N 3.26Å; S34-G37 PolarHBondContact O-N 3.3Å; S34-H38 PolarHBondContact O-CD2 3.19Å; S34-H38 VanDerWaalsContact O-CD2 3.32Å; S34-H38 PolarHBondContact O-N 3.24Å; S34-F406 WeakPolarHBondContact OG-CA 3.29Å; S34-F406 PolarHBondContact OG-N 3.28Å; S34-T409 PolarHBondContact OG-OG1 3.1Å
35	F	95.1	Very high	93.2	Very high	61 Å²	61	48.1 Å²	48.1	27%	0.268	23%	0.234	S	C	.	.	H	α-helix	trans	-60.5	-50.3	177.8	-175.9	-85	0	0	0	111.6	G31 I32 G37 H38 F39 C181 L185 I189	G31-F35 PolarHBondContact O-N 2.85Å; I32-F35 WeakPolarHBondContact O-CB 3.44Å; I32-F35 PolarHBondContact O-N 2.9Å; F35-G37 VanDerWaalsContact C-N 3.28Å; F35-G37 PolarHBondContact O-N 3.37Å; F35-H38 PolarHBondContact O-N 3.12Å; F35-F39 PolarHBondContact O-N 3.5Å; F35-F39 VanDerWaalsContact O-N 3.11Å; F35-C181 WeakPolarHBondContact CD2-SG 3.36Å; F35-L185 HydrophobicContact CB-CD2 3.93Å; F35-I189 HydrophobicContact CB-CD1 4Å
36	I	96	Very high	93.2	Very high	84 Å²	84	46.6 Å²	46.6	43%	0.431	23%	0.228	S	C	.	.	H	α-helix	trans	-60.4	-42.3	175.7	-66.4	169	0	0	0	110.1	I32 H38 F39 I40	I32-I36 HydrophobicContact CG2-CD1 3.84Å; I32-I36 HydrophobicContact CG2-CG1 4.46Å; I32-I36 WeakPolarHBondContact O-CG1 3.31Å; I32-I36 PolarHBondContact O-N 3.18Å; I36-H38 PolarHBondContact O-N 3.06Å; I36-F39 PolarHBondContact O-N 3.48Å; I36-I40 HydrophobicContact CG2-CD1 3.7Å; I36-I40 HydrophobicContact CG2-CG1 4.29Å; I36-I40 WeakPolarHBondContact O-CG1 3.5Å; I36-I40 PolarHBondContact O-N 3.14Å
37	G	94.4	Very high	92.9	Very high	12 Å²	12	42.6 Å²	42.6	12%	0.124	21%	0.213	C	C	.	.	H	α-helix	trans	-59.1	-43.7	178.7	0	0	0	0	0	113.4	L33 S34 F35 A41 Y413	L33-G37 PolarHBondContact O-N 3.23Å; S34-G37 PolarHBondContact O-N 3.3Å; F35-G37 VanDerWaalsContact C-N 3.28Å; F35-G37 PolarHBondContact O-N 3.37Å; G37-A41 WeakPolarHBondContact O-CB 3.29Å; G37-A41 PolarHBondContact O-N 3.48Å; G37-Y413 PolarHBondContact O-OH 2.55Å
38	H	94.3	Very high	92.6	Very high	0 Å²	0	42.4 Å²	42.4	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-62.8	-43.9	173.6	-84.1	-63	0	0	0	112	S34 F35 I36 I40 A41 F42 I178 W405 T409	S34-H38 PolarHBondContact O-CD2 3.19Å; S34-H38 VanDerWaalsContact O-CD2 3.32Å; S34-H38 PolarHBondContact O-N 3.24Å; F35-H38 PolarHBondContact O-N 3.12Å; I36-H38 PolarHBondContact O-N 3.06Å; H38-I40 PolarHBondContact O-N 3.43Å; H38-A41 PolarHBondContact O-N 2.96Å; H38-F42 WeakPolarHBondContact O-CB 3.46Å; H38-F42 PolarHBondContact O-N 3.22Å; H38-I178 HydrophobicContact CB-CD1 4.21Å; H38-W405 AromaticContact NE2-CE3 3.91Å; H38-W405 PolarHBondContact NE2-O 3.34Å; H38-T409 PolarHBondContact CD2-OG1 3.39Å; H38-T409 PolarHBondContact CE1-N 3.36Å; H38-T409 PolarHBondContact CE1-OG1 2.96Å; H38-T409 VanDerWaalsContact CE1-OG1 3.28Å; H38-T409 PolarHBondContact NE2-OG1 3.15Å
39	F	94.6	Very high	92.3	Very high	110 Å²	110	42.5 Å²	42.5	48%	0.482	21%	0.213	S	C	.	.	H	α-helix	trans	-63.3	-43	179.3	-165.5	-103	0	0	0	112.2	F35 I36 F42 I43	F35-F39 PolarHBondContact O-N 3.5Å; F35-F39 VanDerWaalsContact O-N 3.11Å; I36-F39 PolarHBondContact O-N 3.48Å; F39-F42 PolarHBondContact O-N 3.32Å; F39-I43 HydrophobicContact CD1-CD1 3.61Å; F39-I43 HydrophobicContact CD1-CG1 4.44Å; F39-I43 HydrophobicContact CE1-CD1 3.35Å; F39-I43 HydrophobicContact CE1-CG1 4.29Å; F39-I43 HydrophobicContact CZ-CD1 4.09Å; F39-I43 WeakPolarHBondContact O-CG1 3.25Å; F39-I43 PolarHBondContact O-N 3.37Å
40	I	93.9	Very high	91.7	Very high	76 Å²	76	40.7 Å²	40.7	39%	0.39	21%	0.208	S	C	.	.	H	α-helix	trans	-63.2	-46	174.6	-65.9	169.1	0	0	0	110.3	I36 H38 F42 I43 L44 Y413	I36-I40 HydrophobicContact CG2-CD1 3.7Å; I36-I40 HydrophobicContact CG2-CG1 4.29Å; I36-I40 WeakPolarHBondContact O-CG1 3.5Å; I36-I40 PolarHBondContact O-N 3.14Å; H38-I40 PolarHBondContact O-N 3.43Å; I40-F42 VanDerWaalsContact C-N 3.34Å; I40-F42 PolarHBondContact O-N 2.78Å; I40-I43 PolarHBondContact O-N 3.28Å; I40-L44 HydrophobicContact CG2-CD1 3.79Å; I40-L44 HydrophobicContact CG2-CG 4.18Å; I40-L44 WeakPolarHBondContact O-CB 3.49Å; I40-L44 VanDerWaalsContact O-CG 3.27Å; I40-L44 WeakPolarHBondContact O-CG 3.26Å; I40-L44 PolarHBondContact O-N 3.27Å; I40-Y413 WeakPolarHBondContact CB-OH 3.45Å; I40-Y413 VanDerWaalsContact CG2-OH 3.26Å; I40-Y413 WeakPolarHBondContact CG2-OH 3.49Å
41	A	92.1	Very high	90.9	Very high	1 Å²	1	39.3 Å²	39.3	1%	0.008	20%	0.203	C	C	.	.	H	α-helix	trans	-58.7	-45.8	178.2	0	0	0	0	0	111.6	G37 H38 I43 L44 W45 Y413	G37-A41 WeakPolarHBondContact O-CB 3.29Å; G37-A41 PolarHBondContact O-N 3.48Å; H38-A41 PolarHBondContact O-N 2.96Å; A41-I43 PolarHBondContact O-N 3.45Å; A41-L44 PolarHBondContact O-N 3.48Å; A41-W45 VanDerWaalsContact O-CD1 3.29Å; A41-W45 PolarHBondContact O-N 2.93Å; A41-Y413 HydrophobicContact CB-CE2 4.05Å; A41-Y413 PolarHBondContact N-OH 2.87Å
42	F	93.3	Very high	90	Very high	47 Å²	47	40.3 Å²	40.3	21%	0.206	21%	0.207	C	C	.	.	H	α-helix	trans	-58.9	-46.4	175.5	175.3	-99.3	0	0	0	112.3	H38 F39 I40 T46 E174 F175 I178	H38-F42 WeakPolarHBondContact O-CB 3.46Å; H38-F42 PolarHBondContact O-N 3.22Å; F39-F42 PolarHBondContact O-N 3.32Å; I40-F42 VanDerWaalsContact C-N 3.34Å; I40-F42 PolarHBondContact O-N 2.78Å; F42-T46 WeakPolarHBondContact O-CB 3.49Å; F42-T46 PolarHBondContact O-N 3.38Å; F42-T46 PolarHBondContact O-OG1 3.23Å; F42-E174 HydrophobicContact CD2-CB 3.98Å; F42-F175 HydrophobicContact CE2-CD2 4.35Å; F42-I178 HydrophobicContact CB-CD1 3.8Å; F42-I178 HydrophobicContact CB-CG1 3.72Å; F42-I178 HydrophobicContact CD1-CG1 4.37Å; F42-I178 HydrophobicContact CD2-CG1 3.77Å; F42-I178 HydrophobicContact CG-CD1 4.22Å; F42-I178 HydrophobicContact CG-CG1 3.69Å
43	I	92	Very high	89.1	Confident	72 Å²	72	43.5 Å²	43.5	37%	0.369	22%	0.215	S	C	.	.	H	α-helix	trans	-61	-46.2	176.4	-72	171.4	0	0	0	110.5	F39 I40 A41 T46 T47	F39-I43 HydrophobicContact CD1-CD1 3.61Å; F39-I43 HydrophobicContact CD1-CG1 4.44Å; F39-I43 HydrophobicContact CE1-CD1 3.35Å; F39-I43 HydrophobicContact CE1-CG1 4.29Å; F39-I43 HydrophobicContact CZ-CD1 4.09Å; F39-I43 WeakPolarHBondContact O-CG1 3.25Å; F39-I43 PolarHBondContact O-N 3.37Å; I40-I43 PolarHBondContact O-N 3.28Å; A41-I43 PolarHBondContact O-N 3.45Å; I43-T46 PolarHBondContact O-N 2.91Å; I43-T47 WeakPolarHBondContact O-CB 3.47Å; I43-T47 PolarHBondContact O-N 3.42Å; I43-T47 PolarHBondContact O-OG1 3.35Å
44	L	90.5	Very high	88.2	Confident	26 Å²	26	43.5 Å²	43.5	14%	0.136	22%	0.215	C	C	.	.	H	α-helix	trans	-63.5	-46.2	-178.1	-70.3	175	0	0	0	111.6	I40 A41 Y48 Y413 M416 I426 L430	I40-L44 HydrophobicContact CG2-CD1 3.79Å; I40-L44 HydrophobicContact CG2-CG 4.18Å; I40-L44 WeakPolarHBondContact O-CB 3.49Å; I40-L44 VanDerWaalsContact O-CG 3.27Å; I40-L44 WeakPolarHBondContact O-CG 3.26Å; I40-L44 PolarHBondContact O-N 3.27Å; A41-L44 PolarHBondContact O-N 3.48Å; L44-Y48 VanDerWaalsContact O-CB 3.24Å; L44-Y48 WeakPolarHBondContact O-CB 3.5Å; L44-Y48 PolarHBondContact O-N 3.09Å; L44-Y413 HydrophobicContact CD1-CE1 4.29Å; L44-M416 HydrophobicContact CB-SD 3.96Å; L44-M416 HydrophobicContact CD1-CE 3.77Å; L44-M416 HydrophobicContact CD1-SD 3.84Å; L44-M416 HydrophobicContact CG-SD 4.48Å; L44-I426 HydrophobicContact CD2-CG2 3.95Å; L44-L430 HydrophobicContact CD2-CD1 4.05Å
45	W	90.2	Very high	87.2	Confident	3 Å²	3	45.4 Å²	45.4	1%	0.011	23%	0.225	C	C	.	.	H	α-helix	trans	-64.9	-45.5	176.5	-82.7	115.3	0	0	0	112.5	A41 T47 Y48 I49 L162 I170 E174 S412 L415 M416	A41-W45 VanDerWaalsContact O-CD1 3.29Å; A41-W45 PolarHBondContact O-N 2.93Å; W45-T47 PolarHBondContact O-N 3.03Å; W45-Y48 HydrophobicContact CE3-CD1 4.18Å; W45-Y48 HydrophobicContact CZ3-CD1 4.18Å; W45-Y48 HydrophobicContact CZ3-CE1 4.48Å; W45-Y48 PolarHBondContact O-N 3.14Å; W45-I49 HydrophobicContact CE3-CD1 4.39Å; W45-I49 WeakPolarHBondContact O-CB 3.38Å; W45-I49 VanDerWaalsContact O-CG1 3.25Å; W45-I49 WeakPolarHBondContact O-CG1 3.26Å; W45-I49 PolarHBondContact O-N 3.03Å; W45-L162 HydrophobicContact CZ3-CD2 4.02Å; W45-I170 HydrophobicContact CD2-CG2 3.42Å; W45-I170 VanDerWaalsContact CD2-CG2 3.42Å; W45-I170 HydrophobicContact CE3-CD1 4.48Å; W45-I170 HydrophobicContact CE3-CG2 3.57Å; W45-I170 HydrophobicContact CG-CG2 3.9Å; W45-I170 HydrophobicContact CH2-CD1 3.47Å; W45-I170 VanDerWaalsContact CH2-CD1 3.47Å; W45-I170 HydrophobicContact CH2-CG2 4.1Å; W45-I170 HydrophobicContact CZ2-CD1 4Å; W45-I170 HydrophobicContact CZ2-CG2 3.95Å; W45-I170 HydrophobicContact CZ3-CD1 3.74Å; W45-I170 HydrophobicContact CZ3-CG2 3.91Å; W45-E174 HydrophobicContact CB-CG 4.17Å; W45-E174 HydrophobicContact CG-CG 4.05Å; W45-S412 PolarHBondContact NE1-OG 2.95Å; W45-L415 HydrophobicContact CZ2-CB 3.85Å; W45-M416 HydrophobicContact CZ2-CB 3.9Å
46	T	88.5	Confident	86	Confident	28 Å²	28	45.7 Å²	45.7	17%	0.172	23%	0.229	C	C	.	.	H	α-helix	trans	-62.9	-45	178.5	-61.4	0	0	0	0	110.9	F42 I43 Y48 I49 L50	F42-T46 WeakPolarHBondContact O-CB 3.49Å; F42-T46 PolarHBondContact O-N 3.38Å; F42-T46 PolarHBondContact O-OG1 3.23Å; I43-T46 PolarHBondContact O-N 2.91Å; T46-Y48 PolarHBondContact O-N 2.86Å; T46-I49 PolarHBondContact O-N 3.07Å; T46-L50 HydrophobicContact CG2-CD1 3.53Å; T46-L50 HydrophobicContact CG2-CG 4.12Å; T46-L50 VanDerWaalsContact O-CB 3.24Å; T46-L50 WeakPolarHBondContact O-CB 3.24Å; T46-L50 WeakPolarHBondContact O-CG 3.44Å; T46-L50 PolarHBondContact O-N 3.23Å
47	T	86.8	Confident	85.2	Confident	36 Å²	36	48.6 Å²	48.6	22%	0.221	24%	0.238	C	C	.	.	H	α-helix	trans	-63.5	-41.2	176.8	-60.3	0	0	0	0	111.3	I43 W45 G51 I429 I433	I43-T47 WeakPolarHBondContact O-CB 3.47Å; I43-T47 PolarHBondContact O-N 3.42Å; I43-T47 PolarHBondContact O-OG1 3.35Å; W45-T47 PolarHBondContact O-N 3.03Å; T47-G51 WeakPolarHBondContact O-CA 3.17Å; T47-G51 PolarHBondContact O-N 3.46Å; T47-I429 HydrophobicContact CG2-CG2 3.54Å; T47-I433 HydrophobicContact CG2-CD1 3.7Å
48	Y	85.1	Confident	84.2	Confident	1 Å²	1	55.3 Å²	55.3	0%	0.004	26%	0.26	C	S	.	.	H	α-helix	trans	-61.1	-53.3	174.6	175.5	-105.7	0	0	0	111.3	L44 W45 T46 W52 C160 S161 L162 V422 H425 I426	L44-Y48 VanDerWaalsContact O-CB 3.24Å; L44-Y48 WeakPolarHBondContact O-CB 3.5Å; L44-Y48 PolarHBondContact O-N 3.09Å; W45-Y48 HydrophobicContact CE3-CD1 4.18Å; W45-Y48 HydrophobicContact CZ3-CD1 4.18Å; W45-Y48 HydrophobicContact CZ3-CE1 4.48Å; W45-Y48 PolarHBondContact O-N 3.14Å; T46-Y48 PolarHBondContact O-N 2.86Å; Y48-W52 AromaticContact CD2-CD1 3.65Å; Y48-W52 AromaticContact CD2-NE1 3.75Å; Y48-W52 AromaticContact CE2-CD1 3.35Å; Y48-W52 AromaticContact CE2-NE1 3.2Å; Y48-W52 AromaticContact CZ-CD1 3.69Å; Y48-W52 AromaticContact CZ-NE1 3.8Å; Y48-W52 WeakPolarHBondContact O-CB 3.27Å; Y48-W52 PolarHBondContact O-N 3.47Å; Y48-W52 VanDerWaalsContact O-N 3.09Å; Y48-C160 PolarHBondContact OH-SG 3.21Å; Y48-C160 VanDerWaalsContact OH-SG 3.38Å; Y48-S161 PolarHBondContact OH-OG 2.99Å; Y48-L162 HydrophobicContact CE1-CB 4.36Å; Y48-L162 HydrophobicContact CE1-CD2 4.39Å; Y48-V422 HydrophobicContact CD1-CG1 4.37Å; Y48-V422 HydrophobicContact CD2-CG1 4.03Å; Y48-V422 HydrophobicContact CE1-CG1 4.3Å; Y48-V422 HydrophobicContact CE1-CG2 4.1Å; Y48-V422 HydrophobicContact CE2-CB 4.17Å; Y48-V422 HydrophobicContact CE2-CG1 3.91Å; Y48-V422 HydrophobicContact CE2-CG2 4.07Å; Y48-V422 HydrophobicContact CG-CG1 4.27Å; Y48-H425 HydrophobicContact CD2-CB 4.01Å; Y48-H425 HydrophobicContact CE2-CB 3.57Å; Y48-H425 AromaticContact CE2-ND1 3.77Å; Y48-I426 HydrophobicContact CD2-CD1 4.44Å; Y48-I426 HydrophobicContact CD2-CG1 3.75Å; Y48-I426 HydrophobicContact CG-CD1 4.47Å; Y48-I426 HydrophobicContact CG-CG1 4.1Å
49	I	84.3	Confident	83.3	Confident	2 Å²	2	59.8 Å²	59.8	1%	0.01	28%	0.279	C	S	.	.	H	α-helix	trans	-68.9	-47.4	-174	-65.1	169.4	0	0	0	111.3	W45 T46 R53 Q167 L171	W45-I49 HydrophobicContact CE3-CD1 4.39Å; W45-I49 WeakPolarHBondContact O-CB 3.38Å; W45-I49 VanDerWaalsContact O-CG1 3.25Å; W45-I49 WeakPolarHBondContact O-CG1 3.26Å; W45-I49 PolarHBondContact O-N 3.03Å; T46-I49 PolarHBondContact O-N 3.07Å; I49-R53 PolarHBondContact O-N 3.32Å; I49-Q167 HydrophobicContact CD1-CB 4.26Å; I49-Q167 WeakPolarHBondContact CD1-O 3.16Å; I49-Q167 HydrophobicContact CG1-CB 4.31Å; I49-Q167 HydrophobicContact CG1-CG 4.38Å; I49-Q167 HydrophobicContact CG2-CB 4.45Å; I49-L171 HydrophobicContact CD1-CB 3.87Å; I49-L171 HydrophobicContact CD1-CD1 4.32Å
50	L	83.4	Confident	82.3	Confident	84 Å²	84	56.3 Å²	56.3	44%	0.44	27%	0.268	S	S	.	.	H	α-helix	trans	-72.3	-42.2	178.5	-66	-179.9	0	0	0	111.8	T46 W52 R53 I54	T46-L50 HydrophobicContact CG2-CD1 3.53Å; T46-L50 HydrophobicContact CG2-CG 4.12Å; T46-L50 VanDerWaalsContact O-CB 3.24Å; T46-L50 WeakPolarHBondContact O-CB 3.24Å; T46-L50 WeakPolarHBondContact O-CG 3.44Å; T46-L50 PolarHBondContact O-N 3.23Å; L50-W52 VanDerWaalsContact C-N 3.26Å; L50-W52 PolarHBondContact O-N 3.02Å; L50-R53 WeakPolarHBondContact O-CB 3.35Å; L50-R53 PolarHBondContact O-N 2.83Å; L50-I54 WeakPolarHBondContact O-CG1 3.14Å; L50-I54 PolarHBondContact O-N 3.11Å
51	G	77.4	Confident	81.5	Confident	10 Å²	10	55.9 Å²	55.9	10%	0.103	27%	0.266	C	S	.	.	H	α-helix	trans	-57.3	-41.1	178.4	0	0	0	0	0	111.7	T47 R53 I54 I55	T47-G51 WeakPolarHBondContact O-CA 3.17Å; T47-G51 PolarHBondContact O-N 3.46Å; G51-R53 PolarHBondContact O-N 3.09Å; G51-I54 PolarHBondContact O-N 3.38Å; G51-I55 WeakPolarHBondContact O-CB 3.22Å; G51-I55 VanDerWaalsContact O-CG1 3.26Å; G51-I55 WeakPolarHBondContact O-CG1 3.34Å; G51-I55 PolarHBondContact O-N 3.38Å
52	W	73.5	Confident	80.7	Confident	21 Å²	21	58.8 Å²	58.8	8%	0.08	28%	0.279	C	S	.	.	H	α-helix	trans	-60.8	-43.2	173	-92.9	107.8	0	0	0	113.5	Y48 L50 I54 I55 I56 P158 C160 H425	Y48-W52 AromaticContact CD2-CD1 3.65Å; Y48-W52 AromaticContact CD2-NE1 3.75Å; Y48-W52 AromaticContact CE2-CD1 3.35Å; Y48-W52 AromaticContact CE2-NE1 3.2Å; Y48-W52 AromaticContact CZ-CD1 3.69Å; Y48-W52 AromaticContact CZ-NE1 3.8Å; Y48-W52 WeakPolarHBondContact O-CB 3.27Å; Y48-W52 PolarHBondContact O-N 3.47Å; Y48-W52 VanDerWaalsContact O-N 3.09Å; L50-W52 VanDerWaalsContact C-N 3.26Å; L50-W52 PolarHBondContact O-N 3.02Å; W52-I54 VanDerWaalsContact C-N 3.33Å; W52-I54 PolarHBondContact O-N 3.12Å; W52-I55 HydrophobicContact CZ3-CG2 4.45Å; W52-I55 PolarHBondContact O-N 3Å; W52-I56 HydrophobicContact CE3-CD1 4.41Å; W52-I56 HydrophobicContact CE3-CG1 4.39Å; W52-I56 WeakPolarHBondContact O-CB 3.5Å; W52-I56 WeakPolarHBondContact O-CD1 3.45Å; W52-I56 VanDerWaalsContact O-CG1 3.25Å; W52-I56 WeakPolarHBondContact O-CG1 3.35Å; W52-I56 PolarHBondContact O-N 2.77Å; W52-P158 HydrophobicContact CH2-CB 3.83Å; W52-P158 HydrophobicContact CH2-CG 4.48Å; W52-P158 HydrophobicContact CZ3-CB 3.66Å; W52-P158 HydrophobicContact CZ3-CG 3.92Å; W52-C160 HydrophobicContact CD2-CB 4.39Å; W52-C160 HydrophobicContact CG-CB 4.42Å; W52-H425 AromaticContact CE2-CE1 3.83Å; W52-H425 AromaticContact CE2-CG 3.69Å; W52-H425 AromaticContact CE2-ND1 3.34Å; W52-H425 VanDerWaalsContact CE2-ND1 3.34Å; W52-H425 HydrophobicContact CZ2-CB 4.02Å; W52-H425 AromaticContact CZ2-CD2 3.57Å; W52-H425 AromaticContact CZ2-CE1 3.27Å; W52-H425 WeakPolarHBondContact CZ2-CE1 3.36Å; W52-H425 AromaticContact CZ2-CG 3.34Å; W52-H425 AromaticContact CZ2-ND1 3.17Å; W52-H425 WeakPolarHBondContact CZ2-ND1 3.46Å; W52-H425 AromaticContact CZ2-NE2 3.52Å; W52-H425 AromaticContact NE1-CG 3.48Å; W52-H425 AromaticContact NE1-ND1 3.17Å; W52-H425 PolarHBondContact NE1-ND1 2.79Å; W52-H425 VanDerWaalsContact NE1-ND1 3.17Å
53	R	75.8	Confident	79.4	Confident	124 Å²	124	61.4 Å²	61.4	47%	0.468	29%	0.288	S	S	.	.	H	α-helix	trans	-64.5	-39.4	176.7	-67.6	-176.1	180	-162.1	2.8	111.8	I49 L50 G51 K57 M250	I49-R53 PolarHBondContact O-N 3.32Å; L50-R53 WeakPolarHBondContact O-CB 3.35Å; L50-R53 PolarHBondContact O-N 2.83Å; G51-R53 PolarHBondContact O-N 3.09Å; R53-K57 VanDerWaalsContact O-CB 3.29Å; R53-K57 WeakPolarHBondContact O-CB 3.33Å; R53-K57 PolarHBondContact O-N 3.17Å; R53-M250 VanDerWaalsContact NH2-CE 3.31Å
54	I	76.6	Confident	78.7	Confident	115 Å²	115	64.7 Å²	64.7	59%	0.59	30%	0.3	S	S	*	.	H	α-helix	trans	-64.4	-47	176.2	-65.5	166.8	0	0	0	110.2	L50 G51 W52 I56 K57 W58	L50-I54 WeakPolarHBondContact O-CG1 3.14Å; L50-I54 PolarHBondContact O-N 3.11Å; G51-I54 PolarHBondContact O-N 3.38Å; W52-I54 VanDerWaalsContact C-N 3.33Å; W52-I54 PolarHBondContact O-N 3.12Å; I54-I56 PolarHBondContact O-N 2.75Å; I54-K57 PolarHBondContact O-N 3.07Å; I54-W58 VanDerWaalsContact O-CB 3.26Å; I54-W58 WeakPolarHBondContact O-CB 3.26Å; I54-W58 PolarHBondContact O-N 3.12Å
55	I	73.1	Confident	78	Confident	41 Å²	41	71.1 Å²	71.1	21%	0.21	32%	0.322	C	S	.	.	H	α-helix	trans	-61	-44.3	178.8	-70.2	165.9	0	0	0	111	G51 W52 W58 K59 I429	G51-I55 WeakPolarHBondContact O-CB 3.22Å; G51-I55 VanDerWaalsContact O-CG1 3.26Å; G51-I55 WeakPolarHBondContact O-CG1 3.34Å; G51-I55 PolarHBondContact O-N 3.38Å; W52-I55 HydrophobicContact CZ3-CG2 4.45Å; W52-I55 PolarHBondContact O-N 3Å; I55-W58 PolarHBondContact O-N 3.27Å; I55-K59 HydrophobicContact CG2-CD 4.44Å; I55-K59 WeakPolarHBondContact O-CB 3.44Å; I55-K59 WeakPolarHBondContact O-CG 3.28Å; I55-K59 PolarHBondContact O-N 3.41Å; I55-I429 HydrophobicContact CD1-CD1 4.42Å; I55-I429 HydrophobicContact CD1-CG1 3.94Å
56	I	71.4	Confident	77.2	Confident	67 Å²	67	76.6 Å²	76.6	34%	0.344	35%	0.348	S	S	.	.	H	α-helix	trans	-62.7	-47.7	177.2	-69.1	165.6	0	0	0	110.4	W52 I54 W58 K59 S60	W52-I56 HydrophobicContact CE3-CD1 4.41Å; W52-I56 HydrophobicContact CE3-CG1 4.39Å; W52-I56 WeakPolarHBondContact O-CB 3.5Å; W52-I56 WeakPolarHBondContact O-CD1 3.45Å; W52-I56 VanDerWaalsContact O-CG1 3.25Å; W52-I56 WeakPolarHBondContact O-CG1 3.35Å; W52-I56 PolarHBondContact O-N 2.77Å; I54-I56 PolarHBondContact O-N 2.75Å; I56-W58 PolarHBondContact O-N 3.02Å; I56-K59 PolarHBondContact O-N 2.96Å; I56-S60 WeakPolarHBondContact O-CB 3.34Å; I56-S60 PolarHBondContact O-N 2.49Å
57	K	78.4	Confident	76.3	Confident	145 Å²	145	80 Å²	80	63%	0.63	36%	0.364	S	S	*	.	H	α-helix	trans	-60.7	-45.9	177.9	-170.6	176	-179.4	-178.5	0	110.9	R53 I54 S60 I61	R53-K57 VanDerWaalsContact O-CB 3.29Å; R53-K57 WeakPolarHBondContact O-CB 3.33Å; R53-K57 PolarHBondContact O-N 3.17Å; I54-K57 PolarHBondContact O-N 3.07Å; K57-S60 PolarHBondContact O-N 3.16Å; K57-S60 PolarHBondContact O-OG 2.96Å; K57-I61 HydrophobicContact CG-CD1 4.23Å; K57-I61 WeakPolarHBondContact O-CG1 3.21Å; K57-I61 PolarHBondContact O-N 2.94Å
58	W	73.7	Confident	75.5	Confident	153 Å²	153	83.8 Å²	83.8	58%	0.58	38%	0.384	S	S	*	.	H	α-helix	trans	-61.9	-47.7	178.2	-173.1	83.3	0	0	0	112.1	I54 I55 I56 S60 I61 Q62	I54-W58 VanDerWaalsContact O-CB 3.26Å; I54-W58 WeakPolarHBondContact O-CB 3.26Å; I54-W58 PolarHBondContact O-N 3.12Å; I55-W58 PolarHBondContact O-N 3.27Å; I56-W58 PolarHBondContact O-N 3.02Å; W58-S60 VanDerWaalsContact C-N 3.31Å; W58-S60 PolarHBondContact O-N 2.89Å; W58-I61 PolarHBondContact O-N 3.5Å; W58-I61 VanDerWaalsContact O-N 3.14Å; W58-Q62 HydrophobicContact CD2-CG 4.15Å; W58-Q62 HydrophobicContact CE3-CG 4.19Å; W58-Q62 HydrophobicContact CH2-CG 4.15Å; W58-Q62 HydrophobicContact CZ2-CG 4.11Å; W58-Q62 HydrophobicContact CZ3-CG 4.19Å; W58-Q62 WeakPolarHBondContact O-CG 3.31Å; W58-Q62 PolarHBondContact O-N 3.31Å
59	K	74	Confident	74.4	Confident	94 Å²	94	91 Å²	91	41%	0.409	41%	0.412	S	S	.	.	H	α-helix	trans	-61.3	-37.7	174.8	-78.1	-170.4	173.7	-172	0	112.3	I55 I56 I61 Q62 R63 W157 P158	I55-K59 HydrophobicContact CG2-CD 4.44Å; I55-K59 WeakPolarHBondContact O-CB 3.44Å; I55-K59 WeakPolarHBondContact O-CG 3.28Å; I55-K59 PolarHBondContact O-N 3.41Å; I56-K59 PolarHBondContact O-N 2.96Å; K59-I61 VanDerWaalsContact C-N 3.34Å; K59-I61 PolarHBondContact O-N 2.97Å; K59-Q62 PolarHBondContact O-N 3.47Å; K59-R63 PolarHBondContact O-N 3.29Å; K59-W157 HydrophobicContact CB-CZ3 4.48Å; K59-P158 HydrophobicContact CD-CG 4.15Å
60	S	75	Confident	73.4	Confident	36 Å²	36	95.5 Å²	95.5	25%	0.252	44%	0.436	S	S	.	.	H	α-helix	trans	-64.4	-37.3	175	79.2	0	0	0	0	112.8	I56 K57 W58 R63 K64	I56-S60 WeakPolarHBondContact O-CB 3.34Å; I56-S60 PolarHBondContact O-N 2.49Å; K57-S60 PolarHBondContact O-N 3.16Å; K57-S60 PolarHBondContact O-OG 2.96Å; W58-S60 VanDerWaalsContact C-N 3.31Å; W58-S60 PolarHBondContact O-N 2.89Å; S60-R63 PolarHBondContact O-N 3.37Å; S60-K64 WeakPolarHBondContact O-CG 3.5Å; S60-K64 PolarHBondContact O-N 3.04Å
61	I	75.7	Confident	72.1	Confident	68 Å²	68	98 Å²	98	35%	0.349	44%	0.443	S	S	.	.	H	α-helix	trans	-68.6	-43.9	175.5	-68.5	165.1	0	0	0	110.3	K57 W58 K59 R63 K64 R65	K57-I61 HydrophobicContact CG-CD1 4.23Å; K57-I61 WeakPolarHBondContact O-CG1 3.21Å; K57-I61 PolarHBondContact O-N 2.94Å; W58-I61 PolarHBondContact O-N 3.5Å; W58-I61 VanDerWaalsContact O-N 3.14Å; K59-I61 VanDerWaalsContact C-N 3.34Å; K59-I61 PolarHBondContact O-N 2.97Å; I61-R63 VanDerWaalsContact C-N 3.29Å; I61-R63 PolarHBondContact O-N 3.44Å; I61-K64 PolarHBondContact O-N 3.43Å; I61-R65 WeakPolarHBondContact O-CG 3.45Å; I61-R65 PolarHBondContact O-N 3Å
62	Q	75.2	Confident	71	Confident	61 Å²	61	104.7 Å²	104.7	29%	0.285	47%	0.474	S	S	.	.	H	α-helix	trans	-58.4	-42.2	175.6	-71.2	-66.8	-11.1	0	0	111.5	W58 K59 R65 Q66	W58-Q62 HydrophobicContact CD2-CG 4.15Å; W58-Q62 HydrophobicContact CE3-CG 4.19Å; W58-Q62 HydrophobicContact CH2-CG 4.15Å; W58-Q62 HydrophobicContact CZ2-CG 4.11Å; W58-Q62 HydrophobicContact CZ3-CG 4.19Å; W58-Q62 WeakPolarHBondContact O-CG 3.31Å; W58-Q62 PolarHBondContact O-N 3.31Å; K59-Q62 PolarHBondContact O-N 3.47Å; Q62-R65 WeakPolarHBondContact O-CB 3.38Å; Q62-R65 PolarHBondContact O-N 3.3Å; Q62-Q66 WeakPolarHBondContact O-CG 3.43Å; Q62-Q66 PolarHBondContact O-N 3.33Å
63	R	67.9	Low	70.4	Confident	102 Å²	102	108.7 Å²	108.7	39%	0.385	50%	0.496	S	S	.	.	H	α-helix	trans	-64.2	-41.4	175.4	-168.6	176.5	-176.4	174	-0.1	112.6	K59 S60 I61 R65 Q66 L67	K59-R63 PolarHBondContact O-N 3.29Å; S60-R63 PolarHBondContact O-N 3.37Å; I61-R63 VanDerWaalsContact C-N 3.29Å; I61-R63 PolarHBondContact O-N 3.44Å; R63-R65 VanDerWaalsContact C-N 3.29Å; R63-R65 PolarHBondContact O-N 2.92Å; R63-Q66 PolarHBondContact O-N 2.97Å; R63-L67 HydrophobicContact CG-CD1 4.14Å; R63-L67 HydrophobicContact CG-CG 4.5Å; R63-L67 WeakPolarHBondContact O-CB 3.22Å; R63-L67 WeakPolarHBondContact O-CG 3.32Å; R63-L67 PolarHBondContact O-N 3.03Å
64	K	76.9	Confident	69.4	Low	142 Å²	142	107.7 Å²	107.7	62%	0.617	50%	0.503	S	S	*	.	H	α-helix	trans	-60.9	-39.7	173.6	-74.5	-179.1	178.5	-173	0	111.5	S60 I61 L67 N68	S60-K64 WeakPolarHBondContact O-CG 3.5Å; S60-K64 PolarHBondContact O-N 3.04Å; I61-K64 PolarHBondContact O-N 3.43Å; K64-L67 PolarHBondContact O-N 2.94Å; K64-N68 WeakPolarHBondContact O-CB 3.42Å; K64-N68 VanDerWaalsContact O-CG 3.23Å; K64-N68 PolarHBondContact O-N 3.32Å; K64-N68 PolarHBondContact O-OD1 3.32Å
65	R	74.6	Confident	67.7	Low	160 Å²	160	104.9 Å²	104.9	60%	0.604	49%	0.492	S	S	*	.	H	α-helix	trans	-65.7	-43.9	174.8	-70.1	179.8	-178.8	-175.7	-1	112.1	I61 Q62 R63 N68 Y69	I61-R65 WeakPolarHBondContact O-CG 3.45Å; I61-R65 PolarHBondContact O-N 3Å; Q62-R65 WeakPolarHBondContact O-CB 3.38Å; Q62-R65 PolarHBondContact O-N 3.3Å; R63-R65 VanDerWaalsContact C-N 3.29Å; R63-R65 PolarHBondContact O-N 2.92Å; R65-N68 PolarHBondContact O-N 2.85Å; R65-Y69 VanDerWaalsContact O-CB 3.3Å; R65-Y69 WeakPolarHBondContact O-CB 3.46Å; R65-Y69 PolarHBondContact O-N 3.29Å
66	Q	73	Confident	66.1	Low	118 Å²	118	108 Å²	108	55%	0.551	51%	0.514	S	S	*	.	H	α-helix	trans	-64.1	-41	175.7	-74.1	179.8	-16.4	0	0	112.4	Q62 R63 Y69 N70	Q62-Q66 WeakPolarHBondContact O-CG 3.43Å; Q62-Q66 PolarHBondContact O-N 3.33Å; R63-Q66 PolarHBondContact O-N 2.97Å; Q66-Y69 PolarHBondContact O-N 3.38Å; Q66-N70 WeakPolarHBondContact O-CB 3.4Å; Q66-N70 PolarHBondContact O-N 3.42Å
67	L	70.7	Confident	64.5	Low	100 Å²	100	110 Å²	110	52%	0.524	54%	0.535	S	S	.	.	H	α-helix	trans	-65.4	-42.5	175.3	-74.9	167.9	0	0	0	111.6	R63 K64 Y69 N70 F71	R63-L67 HydrophobicContact CG-CD1 4.14Å; R63-L67 HydrophobicContact CG-CG 4.5Å; R63-L67 WeakPolarHBondContact O-CB 3.22Å; R63-L67 WeakPolarHBondContact O-CG 3.32Å; R63-L67 PolarHBondContact O-N 3.03Å; K64-L67 PolarHBondContact O-N 2.94Å; L67-Y69 VanDerWaalsContact C-N 3.35Å; L67-N70 PolarHBondContact O-N 3.38Å; L67-F71 WeakPolarHBondContact O-CB 3.38Å; L67-F71 PolarHBondContact O-N 3.03Å
68	N	69.5	Low	62.5	Low	116 Å²	116	112.6 Å²	112.6	62%	0.62	54%	0.542	S	S	*	.	H	α-helix	trans	-64.8	-39.4	175	-74.5	0.4	0	0	0	111.8	K64 R65 F71 M72	K64-N68 WeakPolarHBondContact O-CB 3.42Å; K64-N68 VanDerWaalsContact O-CG 3.23Å; K64-N68 PolarHBondContact O-N 3.32Å; K64-N68 PolarHBondContact O-OD1 3.32Å; R65-N68 PolarHBondContact O-N 2.85Å; N68-F71 PolarHBondContact O-N 2.98Å; N68-M72 WeakPolarHBondContact O-CB 3.48Å; N68-M72 PolarHBondContact O-N 3.46Å
69	Y	63.2	Low	60.7	Low	153 Å²	153	111.1 Å²	111.1	60%	0.6	55%	0.55	S	S	*	*	H	α-helix	trans	-65.8	-44	176.1	-169.1	-101.2	0	0	0	111.5	R65 Q66 L67 F71 M72 I73	R65-Y69 VanDerWaalsContact O-CB 3.3Å; R65-Y69 WeakPolarHBondContact O-CB 3.46Å; R65-Y69 PolarHBondContact O-N 3.29Å; Q66-Y69 PolarHBondContact O-N 3.38Å; L67-Y69 VanDerWaalsContact C-N 3.35Å; Y69-F71 VanDerWaalsContact C-N 3.35Å; Y69-F71 PolarHBondContact O-N 3.16Å; Y69-M72 PolarHBondContact O-N 2.93Å; Y69-I73 HydrophobicContact CD1-CD1 3.61Å; Y69-I73 HydrophobicContact CE1-CD1 3.16Å; Y69-I73 HydrophobicContact CE1-CG1 4.37Å; Y69-I73 HydrophobicContact CE2-CD1 4.39Å; Y69-I73 HydrophobicContact CG-CD1 4.39Å; Y69-I73 WeakPolarHBondContact O-CG1 3.21Å; Y69-I73 PolarHBondContact O-N 3.5Å; Y69-I73 VanDerWaalsContact O-N 3.08Å
70	N	62.9	Low	58.5	Low	95 Å²	95	114.7 Å²	114.7	51%	0.508	57%	0.573	S	S	.	*	H	α-helix	trans	-64.7	-38.5	175.5	-71.1	-8.8	0	0	0	111.7	Q66 L67 I73 T74	Q66-N70 WeakPolarHBondContact O-CB 3.4Å; Q66-N70 PolarHBondContact O-N 3.42Å; L67-N70 PolarHBondContact O-N 3.38Å; N70-I73 PolarHBondContact O-N 3.23Å; N70-T74 WeakPolarHBondContact O-CG2 3.49Å; N70-T74 PolarHBondContact O-N 3.43Å; N70-T74 PolarHBondContact O-OG1 3.03Å
71	F	55	Low	56.6	Low	138 Å²	138	118.6 Å²	118.6	61%	0.605	60%	0.595	S	S	*	*	H	α-helix	trans	-65.6	-39.9	175.4	-170.5	-95.7	0	0	0	112	L67 N68 Y69 I73 T74 T75	L67-F71 WeakPolarHBondContact O-CB 3.38Å; L67-F71 PolarHBondContact O-N 3.03Å; N68-F71 PolarHBondContact O-N 2.98Å; Y69-F71 VanDerWaalsContact C-N 3.35Å; Y69-F71 PolarHBondContact O-N 3.16Å; F71-I73 VanDerWaalsContact C-N 3.3Å; F71-I73 PolarHBondContact O-N 2.96Å; F71-T74 PolarHBondContact O-N 3.2Å; F71-T74 PolarHBondContact O-OG1 3.41Å; F71-T75 HydrophobicContact CE1-CG2 4.49Å; F71-T75 HydrophobicContact CZ-CG2 4.28Å; F71-T75 PolarHBondContact O-N 3.44Å; F71-T75 VanDerWaalsContact O-N 3.16Å; F71-T75 PolarHBondContact O-OG1 2.84Å
72	M	55.6	Low	54.4	Low	150 Å²	150	124.7 Å²	124.7	74%	0.739	62%	0.619	S	S	*	*	H	α-helix	trans	-67.4	-29.3	177.6	-165.2	176.2	-179	0	0	112.6	N68 Y69	N68-M72 WeakPolarHBondContact O-CB 3.48Å; N68-M72 PolarHBondContact O-N 3.46Å; Y69-M72 PolarHBondContact O-N 2.93Å
73	I	60.8	Low	52.4	Low	105 Å²	105	128.2 Å²	128.2	54%	0.538	64%	0.644	S	S	.	*	H	α-helix	trans	-83.7	-32	176.3	-65.5	173.1	0	0	0	112	Y69 N70 F71	Y69-I73 HydrophobicContact CD1-CD1 3.61Å; Y69-I73 HydrophobicContact CE1-CD1 3.16Å; Y69-I73 HydrophobicContact CE1-CG1 4.37Å; Y69-I73 HydrophobicContact CE2-CD1 4.39Å; Y69-I73 HydrophobicContact CG-CD1 4.39Å; Y69-I73 WeakPolarHBondContact O-CG1 3.21Å; Y69-I73 PolarHBondContact O-N 3.5Å; Y69-I73 VanDerWaalsContact O-N 3.08Å; N70-I73 PolarHBondContact O-N 3.23Å; F71-I73 VanDerWaalsContact C-N 3.3Å; F71-I73 PolarHBondContact O-N 2.96Å
74	T	53.9	Low	50.7	Low	103 Å²	103	128.8 Å²	128.8	63%	0.632	66%	0.66	S	S	*	*	H	α-helix	trans	-86.5	-6.1	-179.2	56.5	0	0	0	0	114.4	N70 F71 P76	N70-T74 WeakPolarHBondContact O-CG2 3.49Å; N70-T74 PolarHBondContact O-N 3.43Å; N70-T74 PolarHBondContact O-OG1 3.03Å; F71-T74 PolarHBondContact O-N 3.2Å; F71-T74 PolarHBondContact O-OG1 3.41Å; T74-P76 VanDerWaalsContact C-CD 3.5Å; T74-P76 WeakPolarHBondContact O-CD 3.28Å
75	T	40.5	Very low	48.6	Very low	56 Å²	56	127.9 Å²	127.9	34%	0.344	67%	0.666	S	S	.	*			trans	-114.6	81.4	171.2	46.2	0	0	0	0	111.2	F71 S77	F71-T75 HydrophobicContact CE1-CG2 4.49Å; F71-T75 HydrophobicContact CZ-CG2 4.28Å; F71-T75 PolarHBondContact O-N 3.44Å; F71-T75 VanDerWaalsContact O-N 3.16Å; F71-T75 PolarHBondContact O-OG1 2.84Å; T75-S77 PolarHBondContact O-N 3.32Å
76	P	40.5	Very low	46.5	Very low	106 Å²	106	126.2 Å²	126.2	69%	0.688	67%	0.674	S	S	*	*			trans	-66	122.3	160	28	-29.2	0	0	0	107.9	T74 Y78	T74-P76 VanDerWaalsContact C-CD 3.5Å; T74-P76 WeakPolarHBondContact O-CD 3.28Å; P76-Y78 PolarHBondContact O-N 2.91Å
77	S	37.2	Very low	44.5	Very low	110 Å²	110	126 Å²	126	77%	0.769	68%	0.68	S	S	*	*			trans	-35.4	107.6	172.5	-48	0	0	0	0	112.4	T75 T79	T75-S77 PolarHBondContact O-N 3.32Å; S77-T79 PolarHBondContact O-N 2.99Å; S77-T79 VanDerWaalsContact O-N 3.16Å
78	Y	37.4	Very low	42.8	Very low	198 Å²	198	128.2 Å²	128.2	78%	0.776	70%	0.699	S	S	*	*			trans	-76.6	98.4	160.6	33.9	-89	0	0	0	107.3	P76 L80	P76-Y78 PolarHBondContact O-N 2.91Å; Y78-L80 PolarHBondContact O-N 3.46Å; Y78-L80 VanDerWaalsContact O-N 3.09Å
79	T	34.6	Very low	41.1	Very low	123 Å²	123	128.4 Å²	128.4	76%	0.755	70%	0.704	S	S	*	*			trans	-60.8	108.1	170.4	-27.4	0	0	0	0	108.4	S77 T81	S77-T79 PolarHBondContact O-N 2.99Å; S77-T79 VanDerWaalsContact O-N 3.16Å; T79-T81 PolarHBondContact O-N 3.24Å; T79-T81 VanDerWaalsContact O-N 3.09Å
80	L	29.5	Very low	39.9	Very low	169 Å²	169	130.5 Å²	130.5	89%	0.885	72%	0.721	S	S	*	*			trans	-68.4	101.4	174.7	-158.5	99.1	0	0	0	108.5	Y78	Y78-L80 PolarHBondContact O-N 3.46Å; Y78-L80 VanDerWaalsContact O-N 3.09Å
81	T	33.3	Very low	38.7	Very low	118 Å²	118	132 Å²	132	72%	0.724	73%	0.734	S	S	*	*			trans	-119.2	109.4	172.3	-26.3	0	0	0	0	108.7	T79	T79-T81 PolarHBondContact O-N 3.24Å; T79-T81 VanDerWaalsContact O-N 3.09Å
82	K	30	Very low	37.8	Very low	196 Å²	196	130.8 Å²	130.8	85%	0.852	74%	0.74	S	S	*	*			trans	-85.7	113.1	-179.9	-172.5	-175.2	-172.8	-177	0	108.4
83	V	34.3	Very low	36.9	Very low	134 Å²	134	129 Å²	129	81%	0.812	74%	0.742	S	S	*	*			trans	-140.3	129.8	165.9	-174.4	0	0	0	0	110
84	T	31.5	Very low	35.4	Very low	115 Å²	115	129.8 Å²	129.8	71%	0.706	75%	0.753	S	S	*	*			trans	-79.6	176.5	-171.6	-47.1	0	0	0	0	112.8
85	T	32.6	Very low	34.6	Very low	122 Å²	122	132.1 Å²	132.1	75%	0.748	77%	0.767	S	S	*	*			trans	86.2	134.6	159.7	7.7	0	0	0	0	116.1
86	T	31.6	Very low	34.3	Very low	125 Å²	125	135.1 Å²	135.1	77%	0.767	79%	0.785	S	S	*	*			cis	-164.3	163.3	14.5	-28.8	0	0	0	0	109.3
87	T	29.7	Very low	34.1	Very low	113 Å²	113	138.8 Å²	138.8	69%	0.693	80%	0.798	S	S	*	*			trans	-50.8	147.6	-178.1	-14.5	0	0	0	0	118.1
88	T	36.3	Very low	34	Very low	148 Å²	148	140.3 Å²	140.3	91%	0.908	80%	0.796	S	S	*	*				-167.3	121.9	122.8	4.2	0	0	0	0	112
89	T	33.3	Very low	34.1	Very low	119 Å²	119	138.2 Å²	138.2	73%	0.73	80%	0.798	S	S	*	*			trans	-85.3	135.6	172.4	13.9	0	0	0	0	110.9
90	M	38.6	Very low	34.1	Very low	197 Å²	197	142.6 Å²	142.6	97%	0.97	80%	0.801	S	S	*	*			trans	-149.6	124.7	139.4	-77.3	-142.9	157.3	0	0	110.5
91	T	36.4	Very low	34.9	Very low	127 Å²	127	141.9 Å²	141.9	78%	0.779	80%	0.798	S	S	*	*			trans	-111.3	-179	170.2	28.3	0	0	0	0	108.1
92	P	37.1	Very low	35.2	Very low	112 Å²	112	143.5 Å²	143.5	73%	0.727	80%	0.802	S	S	*	*			cis	-134.9	176.3	-35.2	33.8	-15.7	0	0	0	112.3
93	S	35.2	Very low	35.6	Very low	112 Å²	112	139.7 Å²	139.7	78%	0.783	80%	0.795	S	S	*	*			trans	170.7	116.2	133	56.6	0	0	0	0	115.7
94	T	30.8	Very low	35.8	Very low	123 Å²	123	140.5 Å²	140.5	76%	0.755	80%	0.795	S	S	*	*			trans	15.5	130.9	139.4	-30.1	0	0	0	0	123.1
95	T	36.8	Very low	36	Very low	151 Å²	151	140 Å²	140	93%	0.926	80%	0.796	S	S	*	*			trans	-152	121.6	131.5	11	0	0	0	0	111.1
96	T	33.5	Very low	36.3	Very low	119 Å²	119	138.9 Å²	138.9	73%	0.73	79%	0.794	S	S	*	*			trans	-105.2	138.1	170.6	38.1	0	0	0	0	110.1
97	L	37.6	Very low	36.5	Very low	184 Å²	184	144.1 Å²	144.1	96%	0.963	80%	0.799	S	S	*	*			trans	-131.6	116.3	159.3	-102.3	160.8	0	0	0	109.3
98	I	34.9	Very low	36.9	Very low	141 Å²	141	147.5 Å²	147.5	72%	0.723	81%	0.807	S	S	*	*			trans	-94.4	138.4	173.5	-67.3	168.3	0	0	0	107.3
99	N	39.6	Very low	36.8	Very low	155 Å²	155	147.5 Å²	147.5	83%	0.829	81%	0.807	S	S	*	*			trans	-137.2	124.1	153.2	-159.9	2.3	0	0	0	110.6
100	R	34.6	Very low	37	Very low	214 Å²	214	149.9 Å²	149.9	81%	0.808	81%	0.81	S	S	*	*			trans	-107.1	135.4	178.2	-96.5	179.1	174.5	154.7	-2.4	107.9
101	N	44.6	Very low	36.7	Very low	154 Å²	154	145.5 Å²	145.5	82%	0.824	80%	0.799	S	S	*	*			trans	-160	96.5	149.9	-85.3	-26	0	0	0	105.2
102	N	39.6	Very low	36.9	Very low	152 Å²	152	147.3 Å²	147.3	81%	0.813	80%	0.798	S	S	*	*				67.7	137.5	76.6	-141.3	16.2	0	0	0	114.6
103	V	39.6	Very low	36.7	Very low	117 Å²	117	147.7 Å²	147.7	71%	0.709	80%	0.799	S	S	*	*			trans	98.3	92.2	167.1	-165.5	0	0	0	0	118.3
104	N	37.2	Very low	36.8	Very low	150 Å²	150	151.2 Å²	151.2	80%	0.802	81%	0.805	S	S	*	*				28.8	120.2	128.8	-60	-15.5	0	0	0	120
105	S	36.9	Very low	37.1	Very low	105 Å²	105	151.1 Å²	151.1	73%	0.734	80%	0.804	S	S	*	*				155.9	125.3	102.7	-174.5	0	0	0	0	112
106	S	38.2	Very low	37.2	Very low	99 Å²	99	152.9 Å²	152.9	69%	0.692	80%	0.799	S	S	*	*			trans	60.2	124.4	146.9	63.8	0	0	0	0	121.3
107	R	37	Very low	37.3	Very low	234 Å²	234	153.5 Å²	153.5	88%	0.883	80%	0.803	S	S	*	*			trans	94.5	127.1	144.2	-79.5	178.2	174.1	173	-0.8	119.5
108	Q	36.9	Very low	37.4	Very low	184 Å²	184	149.9 Å²	149.9	86%	0.86	79%	0.788	S	S	*	*			trans	83.6	90	153.3	-72.1	179	-19.9	0	0	118.2	Q110	Q108-Q110 PolarHBondContact O-N 3.47Å
109	T	33.9	Very low	37.5	Very low	149 Å²	149	147.4 Å²	147.4	91%	0.914	79%	0.789	S	S	*	*			trans	-70.2	105.9	153.3	-20.2	0	0	0	0	109.4
110	Q	37.9	Very low	37.4	Very low	168 Å²	168	146 Å²	146	79%	0.785	79%	0.786	S	S	*	*			trans	-133	111.3	153.4	-111.1	-177.7	4.8	0	0	107.8	Q108 H112	Q108-Q110 PolarHBondContact O-N 3.47Å; Q110-H112 PolarHBondContact O-N 3.25Å
111	S	32.4	Very low	37.4	Very low	105 Å²	105	142 Å²	142	73%	0.734	79%	0.786	S	S	*	*			trans	-80.7	106.8	174.6	159.9	0	0	0	0	109.3
112	H	40	Very low	37.1	Very low	165 Å²	165	140.8 Å²	140.8	76%	0.764	78%	0.784	S	S	*	*			trans	-115	107.8	158.7	-85.1	-67.9	0	0	0	109	Q110 M114	Q110-H112 PolarHBondContact O-N 3.25Å; H112-M114 PolarHBondContact O-N 2.87Å
113	T	33.3	Very low	36.7	Very low	121 Å²	121	140 Å²	140	74%	0.742	79%	0.785	S	S	*	*			trans	-80.7	107.5	166.9	-42.1	0	0	0	0	108.1
114	M	38.3	Very low	36.5	Very low	185 Å²	185	139.1 Å²	139.1	91%	0.911	79%	0.789	S	S	*	*			trans	-91.3	117.1	161.7	-80.9	-163.1	-166.6	0	0	108.8	H112	H112-M114 PolarHBondContact O-N 2.87Å
115	T	37.1	Very low	36.4	Very low	121 Å²	121	138.6 Å²	138.6	74%	0.742	79%	0.792	S	S	*	*			trans	-95	108.5	166.5	-48.7	0	0	0	0	108.5
116	K	37.6	Very low	36.1	Very low	189 Å²	189	139.9 Å²	139.9	82%	0.822	80%	0.795	S	S	*	*			trans	-76	116.3	170.9	-175.8	179.7	-178.4	179.8	0	108.7
117	V	37	Very low	35.9	Very low	132 Å²	132	140.4 Å²	140.4	80%	0.8	80%	0.797	S	S	*	*			trans	-99.2	111	168.7	179.8	0	0	0	0	107.9
118	T	39.5	Very low	35.5	Very low	107 Å²	107	136 Å²	136	66%	0.656	80%	0.796	S	S	*	*			trans	-80.6	126.7	169.6	-55.9	0	0	0	0	108.4
119	A	35.7	Very low	35.4	Very low	90 Å²	90	133.1 Å²	133.1	74%	0.744	79%	0.791	S	S	*	*			trans	-74.5	134.6	173.3	0	0	0	0	0	110.5
120	T	37.7	Very low	35.1	Very low	126 Å²	126	132.9 Å²	132.9	77%	0.773	79%	0.789	S	S	*	*			trans	-114.6	112	166.1	-48.3	0	0	0	0	108.1
121	T	35.3	Very low	34.9	Very low	129 Å²	129	132.6 Å²	132.6	79%	0.791	79%	0.792	S	S	*	*			trans	-80.3	126.7	173.2	-42.2	0	0	0	0	108.4
122	T	37.4	Very low	34.8	Very low	129 Å²	129	134.8 Å²	134.8	79%	0.791	80%	0.795	S	S	*	*			trans	-125.9	115.9	168.4	-33.1	0	0	0	0	108.3
123	T	31.7	Very low	34.3	Very low	136 Å²	136	137.3 Å²	137.3	83%	0.834	80%	0.798	S	S	*	*			trans	-87.4	127.9	175.2	-22.6	0	0	0	0	108.2
124	A	34.9	Very low	34.4	Very low	97 Å²	97	138.6 Å²	138.6	80%	0.802	80%	0.801	S	S	*	*			trans	-134.7	126.9	167.1	0	0	0	0	0	109.2
125	T	35.7	Very low	34.1	Very low	140 Å²	140	137.6 Å²	137.6	86%	0.859	80%	0.799	S	S	*	*			trans	-74.8	143.8	-175.2	19.8	0	0	0	0	112.5
126	T	31.1	Very low	34.1	Very low	131 Å²	131	137.4 Å²	137.4	80%	0.804	80%	0.797	S	S	*	*			trans	-65.3	149.3	178.4	-12	0	0	0	0	113.3
127	P	32.7	Very low	34	Very low	111 Å²	111	133.8 Å²	133.8	72%	0.721	79%	0.787	S	S	*	*			trans	-107	126.2	142.3	29.7	-19	0	0	0	110.1
128	T	29.5	Very low	34.2	Very low	141 Å²	141	132.4 Å²	132.4	87%	0.865	78%	0.783	S	S	*	*			trans	-66.9	121.6	166.9	14.3	0	0	0	0	110.1
129	T	33.9	Very low	34.3	Very low	123 Å²	123	131.3 Å²	131.3	76%	0.755	78%	0.78	S	S	*	*			trans	-118	109	163.6	39	0	0	0	0	109.8
130	T	28.4	Very low	34.6	Very low	144 Å²	144	134.3 Å²	134.3	88%	0.883	78%	0.776	S	S	*	*			trans	-68.5	120.8	162.2	24	0	0	0	0	109.5
131	I	34.7	Very low	34.6	Very low	163 Å²	163	135 Å²	135	84%	0.836	77%	0.771	S	S	*	*			trans	-128.2	131.1	164	-62.7	-178.5	0	0	0	109.3
132	N	29.8	Very low	34.9	Very low	150 Å²	150	134 Å²	134	80%	0.802	76%	0.759	S	S	*	*			trans	-72.9	154.9	-163.9	-161.8	3	0	0	0	113.6
133	R	29.6	Very low	35	Very low	218 Å²	218	134 Å²	134	82%	0.823	75%	0.75	S	S	*	*			trans	-58.5	132.7	167.8	-77.4	172.8	166.9	140.1	-4.3	109.9
134	N	34.4	Very low	35.2	Very low	149 Å²	149	130.2 Å²	130.2	80%	0.797	73%	0.729	S	S	*	*				169.8	134.5	121.4	-80.9	-18	0	0	0	111.4
135	N	32.7	Very low	35.2	Very low	164 Å²	164	130.9 Å²	130.9	88%	0.877	72%	0.718	S	S	*	*			trans	70.1	150.9	162.6	-92.9	-17.9	0	0	0	119.7
136	V	36.4	Very low	35.3	Very low	117 Å²	117	129.8 Å²	129.8	71%	0.709	71%	0.706	S	S	*	*			trans	104.3	86.4	164.2	-164.4	0	0	0	0	116.1
137	N	36.1	Very low	35.5	Very low	113 Å²	113	129.1 Å²	129.1	60%	0.604	70%	0.696	S	S	*	*			trans	72.1	97	138.3	-61.9	-3.7	0	0	0	119.4	S139 K140	N137-S139 PolarHBondContact O-N 3.4Å; N137-K140 PolarHBondContact O-N 3.29Å
138	S	40.7	Very low	35.6	Very low	102 Å²	102	128.8 Å²	128.8	71%	0.713	69%	0.692	S	S	*	*	H	α-helix	trans	-49.6	-11.8	168.9	156.2	0	0	0	0	116.4
139	S	42.7	Very low	35.8	Very low	84 Å²	84	127 Å²	127	59%	0.587	68%	0.681	S	S	*	*	H	α-helix	trans	-84.6	-21.4	178.1	56.9	0	0	0	0	114.6	N137	N137-S139 PolarHBondContact O-N 3.4Å
140	K	40.2	Very low	35.8	Very low	154 Å²	154	125.7 Å²	125.7	67%	0.67	67%	0.673	S	S	*	*	H	α-helix	trans	-89.4	-24.7	-178.2	-74.8	-176.1	176.7	179.7	0	114.2	N137 Q143 S144	N137-K140 PolarHBondContact O-N 3.29Å; K140-Q143 PolarHBondContact O-N 3.45Å; K140-S144 PolarHBondContact O-N 3.35Å
141	Q	38.9	Very low	35.9	Very low	141 Å²	141	124.5 Å²	124.5	66%	0.659	67%	0.666	S	S	*	*	H	α-helix	trans	-72.3	-28.1	177.6	-85.1	-174.7	-14.3	0	0	113.4	Q143 S144 I145	Q141-Q143 VanDerWaalsContact C-N 3.33Å; Q141-S144 WeakPolarHBondContact CA-OG 3.25Å; Q141-S144 PolarHBondContact O-N 2.72Å; Q141-S144 PolarHBondContact O-OG 2.81Å; Q141-I145 WeakPolarHBondContact O-CD1 3.44Å; Q141-I145 VanDerWaalsContact O-CG1 3.29Å; Q141-I145 WeakPolarHBondContact O-CG1 3.45Å; Q141-I145 PolarHBondContact O-N 2.9Å; Q141-I145 VanDerWaalsContact O-N 3.15Å
142	I	41.1	Very low	35.5	Very low	107 Å²	107	126.9 Å²	126.9	55%	0.549	67%	0.67	S	S	.	*	H	α-helix	trans	-68.8	-34.8	174.6	-62.4	172.7	0	0	0	110.5	I146	I142-I146 HydrophobicContact CG2-CD1 4.07Å; I142-I146 WeakPolarHBondContact O-CD1 3.44Å; I142-I146 VanDerWaalsContact O-CG1 3.31Å; I142-I146 WeakPolarHBondContact O-CG1 2.86Å; I142-I146 PolarHBondContact O-N 3.38Å
143	Q	39.2	Very low	35.6	Very low	128 Å²	128	127.1 Å²	127.1	60%	0.598	67%	0.666	S	S	*	*	H	α-helix	trans	-71	-36.5	174.4	-77.6	-179.7	-5.8	0	0	112.7	K140 Q141 I146 I147	K140-Q143 PolarHBondContact O-N 3.45Å; Q141-Q143 VanDerWaalsContact C-N 3.33Å; Q143-I146 PolarHBondContact O-N 3.49Å; Q143-I147 WeakPolarHBondContact O-CB 3.09Å; Q143-I147 VanDerWaalsContact O-CD1 3.25Å; Q143-I147 WeakPolarHBondContact O-CD1 3.11Å; Q143-I147 WeakPolarHBondContact O-CG1 3.38Å; Q143-I147 PolarHBondContact O-N 2.87Å
144	S	35.6	Very low	35.6	Very low	57 Å²	57	122.2 Å²	122.2	40%	0.399	66%	0.661	S	S	.	*	H	α-helix	trans	-69.4	-33.6	176.6	54.2	0	0	0	0	113.1	K140 Q141 I147 T148	K140-S144 PolarHBondContact O-N 3.35Å; Q141-S144 WeakPolarHBondContact CA-OG 3.25Å; Q141-S144 PolarHBondContact O-N 2.72Å; Q141-S144 PolarHBondContact O-OG 2.81Å; S144-I147 PolarHBondContact O-N 3.31Å; S144-T148 PolarHBondContact O-N 3.32Å; S144-T148 PolarHBondContact O-OG1 2.81Å
145	I	36.1	Very low	35.4	Very low	112 Å²	112	121.3 Å²	121.3	57%	0.574	66%	0.656	S	S	*	*	H	α-helix	trans	-72.8	-29.5	179.2	-66.6	165.8	0	0	0	112	Q141 I147 T149	Q141-I145 WeakPolarHBondContact O-CD1 3.44Å; Q141-I145 VanDerWaalsContact O-CG1 3.29Å; Q141-I145 WeakPolarHBondContact O-CG1 3.45Å; Q141-I145 PolarHBondContact O-N 2.9Å; Q141-I145 VanDerWaalsContact O-N 3.15Å; I145-I147 VanDerWaalsContact C-N 3.33Å; I145-T149 PolarHBondContact O-OG1 3.5Å
146	I	37.2	Very low	35.7	Very low	117 Å²	117	120 Å²	120	60%	0.6	65%	0.647	S	S	*	*	H	α-helix	trans	-75.7	-23.1	173.1	-64.8	168.3	0	0	0	111.6	I142 Q143	I142-I146 HydrophobicContact CG2-CD1 4.07Å; I142-I146 WeakPolarHBondContact O-CD1 3.44Å; I142-I146 VanDerWaalsContact O-CG1 3.31Å; I142-I146 WeakPolarHBondContact O-CG1 2.86Å; I142-I146 PolarHBondContact O-N 3.38Å; Q143-I146 PolarHBondContact O-N 3.49Å
147	I	35.8	Very low	35.9	Very low	117 Å²	117	119.9 Å²	119.9	60%	0.6	63%	0.634	S	S	*	*	H	α-helix	trans	-97.8	-25.5	-174.7	-64.9	168.5	0	0	0	112.7	Q143 S144 I145 T150	Q143-I147 WeakPolarHBondContact O-CB 3.09Å; Q143-I147 VanDerWaalsContact O-CD1 3.25Å; Q143-I147 WeakPolarHBondContact O-CD1 3.11Å; Q143-I147 WeakPolarHBondContact O-CG1 3.38Å; Q143-I147 PolarHBondContact O-N 2.87Å; S144-I147 PolarHBondContact O-N 3.31Å; I145-I147 VanDerWaalsContact C-N 3.33Å; I147-T150 PolarHBondContact O-OG1 3.13Å; I147-T150 VanDerWaalsContact O-OG1 3.09Å
148	T	33.6	Very low	36.6	Very low	104 Å²	104	116.2 Å²	116.2	64%	0.638	62%	0.616	S	S	*	*	T	Hydrogen-bonded Turn	trans	-90.3	-3.2	-179.2	47.4	0	0	0	0	115.3	S144	S144-T148 PolarHBondContact O-N 3.32Å; S144-T148 PolarHBondContact O-OG1 2.81Å
149	T	33.7	Very low	37.3	Very low	104 Å²	104	118.1 Å²	118.1	64%	0.638	62%	0.617	S	S	*	*	T	Hydrogen-bonded Turn	trans	-88.8	-1.4	172.5	35.9	0	0	0	0	114	I145 T151	I145-T149 PolarHBondContact O-OG1 3.5Å; T149-T151 PolarHBondContact O-N 3.38Å
150	T	34.3	Very low	38	Very low	95 Å²	95	115.1 Å²	115.1	58%	0.583	60%	0.596	S	S	*	*			trans	-95.2	61.7	176.5	55.5	0	0	0	0	112.2	I147	I147-T150 PolarHBondContact O-OG1 3.13Å; I147-T150 VanDerWaalsContact O-OG1 3.09Å
151	T	30.3	Very low	39.2	Very low	119 Å²	119	110.3 Å²	110.3	73%	0.73	58%	0.581	S	S	*	*	S	Bend	trans	-88.2	106.6	166.7	36.5	0	0	0	0	109.4	T149 E153	T149-T151 PolarHBondContact O-N 3.38Å; T151-E153 PolarHBondContact O-N 3.22Å
152	K	27.7	Very low	40.9	Very low	212 Å²	212	104.7 Å²	104.7	92%	0.922	56%	0.556	S	S	*	*	S	Bend	trans	57.7	33	167	-77.1	-176.1	175.2	176.9	0	117.5	T154	K152-T154 PolarHBondContact O-N 2.85Å
153	E	30.8	Very low	42.7	Very low	155 Å²	155	102.4 Å²	102.4	72%	0.724	54%	0.54	S	S	*	.			trans	-71.6	116.9	160.5	-74.7	-168.8	155.8	0	0	109.3	T151 L155	T151-E153 PolarHBondContact O-N 3.22Å; E153-L155 PolarHBondContact O-N 3.47Å; E153-L155 VanDerWaalsContact O-N 3.07Å
154	T	29.1	Very low	44.6	Very low	115 Å²	115	98.4 Å²	98.4	71%	0.706	52%	0.523	S	S	*	.			trans	-45.3	119	163.3	37.1	0	0	0	0	108	K152 I156	K152-T154 PolarHBondContact O-N 2.85Å; T154-I156 WeakPolarHBondContact O-CG1 3.3Å; T154-I156 PolarHBondContact O-N 3.37Å
155	L	31.5	Very low	47	Very low	131 Å²	131	96 Å²	96	69%	0.686	51%	0.506	S	S	*	.			trans	-68.2	78.4	-175.3	-139	98.2	0	0	0	109.4	E153 W157	E153-L155 PolarHBondContact O-N 3.47Å; E153-L155 VanDerWaalsContact O-N 3.07Å; L155-W157 PolarHBondContact O-N 2.89Å
156	I	38.2	Very low	49.4	Very low	136 Å²	136	91.5 Å²	91.5	70%	0.697	48%	0.483	S	S	*	.			trans	-75.9	112.8	176.8	-64.9	163.8	0	0	0	106	T154	T154-I156 WeakPolarHBondContact O-CG1 3.3Å; T154-I156 PolarHBondContact O-N 3.37Å
157	W	40.9	Very low	51.8	Low	114 Å²	114	86.3 Å²	86.3	43%	0.432	46%	0.456	S	S	.	.			trans	-53.6	137.6	172.9	-70.6	93.6	0	0	0	109.2	K59 L155 I159	K59-W157 HydrophobicContact CB-CZ3 4.48Å; L155-W157 PolarHBondContact O-N 2.89Å; W157-I159 PolarHBondContact O-N 2.98Å
158	P	51.7	Low	54.3	Low	37 Å²	37	82.1 Å²	82.1	24%	0.24	44%	0.436	C	S	.	.			trans	-67.2	103.6	172.2	30.2	-34.3	0	0	0	107.6	W52 K59 C160	W52-P158 HydrophobicContact CH2-CB 3.83Å; W52-P158 HydrophobicContact CH2-CG 4.48Å; W52-P158 HydrophobicContact CZ3-CB 3.66Å; W52-P158 HydrophobicContact CZ3-CG 3.92Å; K59-P158 HydrophobicContact CD-CG 4.15Å; P158-C160 PolarHBondContact O-N 3.41Å
159	I	53.6	Low	57.1	Low	142 Å²	142	77.2 Å²	77.2	73%	0.728	41%	0.406	S	S	*	.			trans	-70.9	122.7	174.2	-57.2	173.1	0	0	0	105.5	W157 S161	W157-I159 PolarHBondContact O-N 2.98Å; I159-S161 PolarHBondContact O-N 3.09Å; I159-S161 VanDerWaalsContact O-N 3.12Å
160	C	58	Low	59.8	Low	21 Å²	21	72.4 Å²	72.4	14%	0.142	38%	0.376	C	S	.	.			trans	-56	125.3	171.8	-172.3	0	0	0	0	107.7	Y48 W52 P158 L162 Q167	Y48-C160 PolarHBondContact OH-SG 3.21Å; Y48-C160 VanDerWaalsContact OH-SG 3.38Å; W52-C160 HydrophobicContact CD2-CB 4.39Å; W52-C160 HydrophobicContact CG-CB 4.42Å; P158-C160 PolarHBondContact O-N 3.41Å; C160-L162 PolarHBondContact O-N 3.39Å; C160-Q167 PolarHBondContact SG-NE2 2.86Å
161	S	66.4	Low	62.6	Low	52 Å²	52	70.6 Å²	70.6	36%	0.364	36%	0.362	S	S	.	.	S	Bend	trans	-65.3	-16.1	-171.2	57.8	0	0	0	0	113.5	Y48 I159 T421	Y48-S161 PolarHBondContact OH-OG 2.99Å; I159-S161 PolarHBondContact O-N 3.09Å; I159-S161 VanDerWaalsContact O-N 3.12Å; S161-T421 WeakPolarHBondContact CB-OG1 3.46Å; S161-T421 WeakPolarHBondContact OG-CB 3.32Å; S161-T421 PolarHBondContact OG-OG1 3.31Å
162	L	73.8	Confident	65.6	Low	23 Å²	23	65.7 Å²	65.7	12%	0.12	33%	0.333	C	S	.	.	S	Bend	trans	-104.9	131.8	-179.7	-159.3	67.9	0	0	0	109.7	W45 Y48 C160 I166 Q167 I170	W45-L162 HydrophobicContact CZ3-CD2 4.02Å; Y48-L162 HydrophobicContact CE1-CB 4.36Å; Y48-L162 HydrophobicContact CE1-CD2 4.39Å; C160-L162 PolarHBondContact O-N 3.39Å; L162-I166 HydrophobicContact CD1-CB 4.21Å; L162-I166 HydrophobicContact CD1-CD1 4.31Å; L162-I166 HydrophobicContact CD1-CG2 3.79Å; L162-I166 HydrophobicContact CD2-CB 4.39Å; L162-I166 HydrophobicContact CD2-CG2 3.93Å; L162-I166 HydrophobicContact CG-CB 4.01Å; L162-I166 HydrophobicContact CG-CG2 3.89Å; L162-Q167 HydrophobicContact CB-CG 4.02Å; L162-Q167 HydrophobicContact CD2-CG 3.82Å; L162-Q167 HydrophobicContact CG-CG 4.1Å; L162-Q167 PolarHBondContact O-NE2 3.49Å; L162-I170 HydrophobicContact CD2-CD1 3.99Å
163	R	78.2	Confident	68.8	Low	60 Å²	60	55.6 Å²	55.6	23%	0.226	29%	0.289	C	S	.	.			trans	-60.3	145	176.3	-165.2	177.5	-176.3	-144.6	9	110.6	S165 I166 Q167 E231	R163-S165 VanDerWaalsContact C-N 3.25Å; R163-S165 VanDerWaalsContact CD-OG 3.28Å; R163-S165 WeakPolarHBondContact CD-OG 3.01Å; R163-S165 WeakPolarHBondContact CG-OG 3.37Å; R163-S165 PolarHBondContact O-N 2.92Å; R163-I166 HydrophobicContact CB-CD1 4.17Å; R163-I166 HydrophobicContact CB-CG1 4.26Å; R163-I166 PolarHBondContact O-N 2.92Å; R163-I166 VanDerWaalsContact O-N 3.12Å; R163-Q167 WeakPolarHBondContact O-CG 3.42Å; R163-Q167 PolarHBondContact O-N 3.33Å; R163-E231 IonicContact NH1-OE1 2.72Å; R163-E231 PolarHBondContact NH1-OE1 2.93Å
164	L	80.1	Confident	71.8	Confident	44 Å²	44	48.2 Å²	48.2	23%	0.23	26%	0.255	C	S	.	.	H	α-helix	trans	-61.4	-32.7	-175.3	-167.2	57.6	0	0	0	113.5	T168 M250	L164-T168 PolarHBondContact O-N 3.27Å; L164-T168 VanDerWaalsContact O-N 3.07Å; L164-T168 PolarHBondContact O-OG1 3.27Å; L164-M250 HydrophobicContact CD1-CE 3.48Å; L164-M250 VanDerWaalsContact CD1-CE 3.48Å; L164-M250 HydrophobicContact CD2-CE 3.54Å; L164-M250 HydrophobicContact CD2-CG 3.35Å; L164-M250 HydrophobicContact CD2-SD 3.62Å; L164-M250 HydrophobicContact CG-CE 3.3Å; L164-M250 HydrophobicContact CG-CG 3.71Å; L164-M250 HydrophobicContact CG-SD 4.03Å
165	S	85.2	Confident	74.9	Confident	6 Å²	6	48 Å²	48	4%	0.042	24%	0.244	C	C	.	.	H	α-helix	trans	-60.3	-54.6	170.9	46.9	0	0	0	0	111.6	R163 Q167 T168 I169 E231 T253	R163-S165 VanDerWaalsContact C-N 3.25Å; R163-S165 VanDerWaalsContact CD-OG 3.28Å; R163-S165 WeakPolarHBondContact CD-OG 3.01Å; R163-S165 WeakPolarHBondContact CG-OG 3.37Å; R163-S165 PolarHBondContact O-N 2.92Å; S165-Q167 VanDerWaalsContact C-N 3.3Å; S165-Q167 PolarHBondContact O-N 3.22Å; S165-T168 WeakPolarHBondContact O-CB 3.38Å; S165-T168 PolarHBondContact O-N 2.76Å; S165-I169 WeakPolarHBondContact O-CG1 3.38Å; S165-I169 PolarHBondContact O-N 3.3Å; S165-E231 WeakPolarHBondContact CB-OE1 3.25Å; S165-E231 PolarHBondContact OG-OE1 3.43Å; S165-T253 WeakPolarHBondContact CB-OG1 3.33Å
166	I	86.5	Confident	77.9	Confident	17 Å²	17	42.1 Å²	42.1	9%	0.087	21%	0.214	C	C	.	.	H	α-helix	trans	-59.5	-41.6	178.6	-56.4	173.4	0	0	0	110.8	L162 R163 T168 I169 I170 L228 E231 I235	L162-I166 HydrophobicContact CD1-CB 4.21Å; L162-I166 HydrophobicContact CD1-CD1 4.31Å; L162-I166 HydrophobicContact CD1-CG2 3.79Å; L162-I166 HydrophobicContact CD2-CB 4.39Å; L162-I166 HydrophobicContact CD2-CG2 3.93Å; L162-I166 HydrophobicContact CG-CB 4.01Å; L162-I166 HydrophobicContact CG-CG2 3.89Å; R163-I166 HydrophobicContact CB-CD1 4.17Å; R163-I166 HydrophobicContact CB-CG1 4.26Å; R163-I166 PolarHBondContact O-N 2.92Å; R163-I166 VanDerWaalsContact O-N 3.12Å; I166-T168 VanDerWaalsContact C-N 3.29Å; I166-T168 PolarHBondContact O-N 3.21Å; I166-I169 PolarHBondContact O-N 3.34Å; I166-I170 HydrophobicContact CG2-CD1 3.74Å; I166-I170 HydrophobicContact CG2-CG1 4.19Å; I166-I170 WeakPolarHBondContact O-CB 3.34Å; I166-I170 VanDerWaalsContact O-CG1 3.31Å; I166-I170 WeakPolarHBondContact O-CG1 3.42Å; I166-I170 PolarHBondContact O-N 3.37Å; I166-L228 HydrophobicContact CG2-CD1 4.46Å; I166-E231 WeakPolarHBondContact CG1-OE2 3.4Å; I166-I235 HydrophobicContact CD1-CD1 3.88Å
167	Q	88.1	Confident	80.5	Confident	9 Å²	9	35.7 Å²	35.7	4%	0.042	18%	0.181	C	C	.	.	H	α-helix	trans	-57.4	-43.7	174.3	-68.6	176.1	26.2	0	0	112	I49 C160 L162 R163 S165 L171	I49-Q167 HydrophobicContact CD1-CB 4.26Å; I49-Q167 WeakPolarHBondContact CD1-O 3.16Å; I49-Q167 HydrophobicContact CG1-CB 4.31Å; I49-Q167 HydrophobicContact CG1-CG 4.38Å; I49-Q167 HydrophobicContact CG2-CB 4.45Å; C160-Q167 PolarHBondContact SG-NE2 2.86Å; L162-Q167 HydrophobicContact CB-CG 4.02Å; L162-Q167 HydrophobicContact CD2-CG 3.82Å; L162-Q167 HydrophobicContact CG-CG 4.1Å; L162-Q167 PolarHBondContact O-NE2 3.49Å; R163-Q167 WeakPolarHBondContact O-CG 3.42Å; R163-Q167 PolarHBondContact O-N 3.33Å; S165-Q167 VanDerWaalsContact C-N 3.3Å; S165-Q167 PolarHBondContact O-N 3.22Å; Q167-L171 VanDerWaalsContact O-CB 3.3Å; Q167-L171 WeakPolarHBondContact O-CB 3.37Å; Q167-L171 PolarHBondContact O-N 3.48Å
168	T	89.6	Confident	83.1	Confident	29 Å²	29	31.8 Å²	31.8	18%	0.178	17%	0.168	C	C	.	.	H	α-helix	trans	-68.1	-40.6	-178.2	-52.4	0	0	0	0	111	L164 S165 I166 S172 I254 I257	L164-T168 PolarHBondContact O-N 3.27Å; L164-T168 VanDerWaalsContact O-N 3.07Å; L164-T168 PolarHBondContact O-OG1 3.27Å; S165-T168 WeakPolarHBondContact O-CB 3.38Å; S165-T168 PolarHBondContact O-N 2.76Å; I166-T168 VanDerWaalsContact C-N 3.29Å; I166-T168 PolarHBondContact O-N 3.21Å; T168-S172 WeakPolarHBondContact O-CB 3.49Å; T168-S172 PolarHBondContact O-N 3.18Å; T168-I254 HydrophobicContact CG2-CG1 4.48Å; T168-I257 HydrophobicContact CG2-CD1 3.79Å
169	I	91.7	Very high	85.2	Confident	0 Å²	0	32.7 Å²	32.7	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-63.7	-48.7	176.4	-63.1	161.4	0	0	0	110.5	S165 I166 S172 M173 H224 Y227 L228 E231 T253 I257	S165-I169 WeakPolarHBondContact O-CG1 3.38Å; S165-I169 PolarHBondContact O-N 3.3Å; I166-I169 PolarHBondContact O-N 3.34Å; I169-S172 PolarHBondContact O-N 2.66Å; I169-M173 WeakPolarHBondContact O-CB 3.41Å; I169-M173 PolarHBondContact O-N 3.38Å; I169-H224 HydrophobicContact CG2-CB 4.32Å; I169-Y227 HydrophobicContact CD1-CD1 3.39Å; I169-Y227 HydrophobicContact CD1-CE1 3.18Å; I169-Y227 HydrophobicContact CD1-CG 4.45Å; I169-Y227 HydrophobicContact CG1-CD1 3.7Å; I169-Y227 HydrophobicContact CG1-CE1 3.61Å; I169-Y227 HydrophobicContact CG2-CD1 4.32Å; I169-L228 HydrophobicContact CG2-CB 4.09Å; I169-L228 HydrophobicContact CG2-CD1 4.4Å; I169-E231 WeakPolarHBondContact CD1-OE2 3.48Å; I169-T253 HydrophobicContact CD1-CG2 4.1Å; I169-T253 HydrophobicContact CG1-CG2 3.7Å; I169-I257 HydrophobicContact CG1-CD1 4.29Å
170	I	91.2	Very high	87	Confident	4 Å²	4	26 Å²	26	2%	0.021	14%	0.135	C	C	.	.	H	α-helix	trans	-63.8	-44.5	179.8	-66.9	177.3	0	0	0	110.5	W45 L162 I166 S172 M173 E174 L228	W45-I170 HydrophobicContact CD2-CG2 3.42Å; W45-I170 VanDerWaalsContact CD2-CG2 3.42Å; W45-I170 HydrophobicContact CE3-CD1 4.48Å; W45-I170 HydrophobicContact CE3-CG2 3.57Å; W45-I170 HydrophobicContact CG-CG2 3.9Å; W45-I170 HydrophobicContact CH2-CD1 3.47Å; W45-I170 VanDerWaalsContact CH2-CD1 3.47Å; W45-I170 HydrophobicContact CH2-CG2 4.1Å; W45-I170 HydrophobicContact CZ2-CD1 4Å; W45-I170 HydrophobicContact CZ2-CG2 3.95Å; W45-I170 HydrophobicContact CZ3-CD1 3.74Å; W45-I170 HydrophobicContact CZ3-CG2 3.91Å; L162-I170 HydrophobicContact CD2-CD1 3.99Å; I166-I170 HydrophobicContact CG2-CD1 3.74Å; I166-I170 HydrophobicContact CG2-CG1 4.19Å; I166-I170 WeakPolarHBondContact O-CB 3.34Å; I166-I170 VanDerWaalsContact O-CG1 3.31Å; I166-I170 WeakPolarHBondContact O-CG1 3.42Å; I166-I170 PolarHBondContact O-N 3.37Å; I170-S172 VanDerWaalsContact C-N 3.31Å; I170-S172 PolarHBondContact O-N 3.46Å; I170-M173 WeakPolarHBondContact O-CB 3.28Å; I170-M173 PolarHBondContact O-N 3.29Å; I170-E174 HydrophobicContact CG2-CG 4.2Å; I170-E174 WeakPolarHBondContact O-CG 3.49Å; I170-E174 PolarHBondContact O-N 3.12Å; I170-L228 HydrophobicContact CD1-CD1 3.96Å; I170-L228 HydrophobicContact CG1-CD1 3.46Å; I170-L228 VanDerWaalsContact CG1-CD1 3.46Å
171	L	91.7	Very high	88.7	Confident	56 Å²	56	25 Å²	25	29%	0.293	13%	0.129	S	C	.	.	H	α-helix	trans	-60.7	-42	177.7	-173.5	64.7	0	0	0	111.9	I49 Q167 F175	I49-L171 HydrophobicContact CD1-CB 3.87Å; I49-L171 HydrophobicContact CD1-CD1 4.32Å; Q167-L171 VanDerWaalsContact O-CB 3.3Å; Q167-L171 WeakPolarHBondContact O-CB 3.37Å; Q167-L171 PolarHBondContact O-N 3.48Å; L171-F175 WeakPolarHBondContact O-CB 3.46Å; L171-F175 PolarHBondContact O-N 2.94Å
172	S	94.2	Very high	89.9	Confident	16 Å²	16	25.5 Å²	25.5	11%	0.112	13%	0.132	C	C	.	.	H	α-helix	trans	-64.8	-41.7	176.1	-177.4	0	0	0	0	111.9	T168 I169 I170 F175 I176 H224 Y261	T168-S172 WeakPolarHBondContact O-CB 3.49Å; T168-S172 PolarHBondContact O-N 3.18Å; I169-S172 PolarHBondContact O-N 2.66Å; I170-S172 VanDerWaalsContact C-N 3.31Å; I170-S172 PolarHBondContact O-N 3.46Å; S172-F175 PolarHBondContact O-N 3.3Å; S172-I176 WeakPolarHBondContact O-CG2 3.31Å; S172-I176 PolarHBondContact O-N 2.86Å; S172-H224 WeakPolarHBondContact CB-NE2 3.38Å; S172-H224 PolarHBondContact OG-CE1 3.48Å; S172-H224 PolarHBondContact OG-NE2 3.35Å; S172-Y261 PolarHBondContact OG-OH 2.96Å
173	M	93.9	Very high	90.6	Very high	1 Å²	1	25.1 Å²	25.1	1%	0.005	13%	0.13	C	C	.	.	H	α-helix	trans	-62.4	-46.1	175.7	-174.2	-179	174.9	0	0	111.9	I169 I170 I176 N177 H224 F225	I169-M173 WeakPolarHBondContact O-CB 3.41Å; I169-M173 PolarHBondContact O-N 3.38Å; I170-M173 WeakPolarHBondContact O-CB 3.28Å; I170-M173 PolarHBondContact O-N 3.29Å; M173-I176 VanDerWaalsContact O-CG2 3.23Å; M173-I176 WeakPolarHBondContact O-CG2 3.49Å; M173-N177 VanDerWaalsContact O-CB 3.31Å; M173-N177 WeakPolarHBondContact O-CB 3.31Å; M173-N177 PolarHBondContact O-N 3.4Å; M173-N177 PolarHBondContact O-ND2 3.02Å; M173-H224 HydrophobicContact CB-CB 3.89Å; M173-H224 HydrophobicContact CG-CB 4.08Å; M173-H224 HydrophobicContact SD-CB 4.46Å; M173-F225 HydrophobicContact CE-CB 4.02Å; M173-F225 HydrophobicContact CE-CD2 4.37Å; M173-F225 HydrophobicContact SD-CB 4.41Å
174	E	93.5	Very high	91.1	Very high	0 Å²	0	22.3 Å²	22.3	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-66.8	-38.7	177.9	-67.1	-59.7	137.9	0	0	111.8	F42 W45 I170 N177 I178 S412	F42-E174 HydrophobicContact CD2-CB 3.98Å; W45-E174 HydrophobicContact CB-CG 4.17Å; W45-E174 HydrophobicContact CG-CG 4.05Å; I170-E174 HydrophobicContact CG2-CG 4.2Å; I170-E174 WeakPolarHBondContact O-CG 3.49Å; I170-E174 PolarHBondContact O-N 3.12Å; E174-N177 PolarHBondContact O-N 2.97Å; E174-I178 WeakPolarHBondContact O-CG1 3.4Å; E174-I178 PolarHBondContact O-N 3.3Å; E174-S412 VanDerWaalsContact CD-OG 3.23Å; E174-S412 WeakPolarHBondContact OE1-CB 3.18Å; E174-S412 PolarHBondContact OE1-OG 2.89Å
175	F	94.2	Very high	91.6	Very high	110 Å²	110	20.2 Å²	20.2	48%	0.482	11%	0.109	S	C	.	.	H	α-helix	trans	-63.2	-46.9	177.1	-174.9	-102.2	0	0	0	111.9	F42 L171 S172 N177 I178 I179	F42-F175 HydrophobicContact CE2-CD2 4.35Å; L171-F175 WeakPolarHBondContact O-CB 3.46Å; L171-F175 PolarHBondContact O-N 2.94Å; S172-F175 PolarHBondContact O-N 3.3Å; F175-N177 VanDerWaalsContact C-N 3.32Å; F175-N177 PolarHBondContact O-N 3.23Å; F175-I178 PolarHBondContact O-N 3.49Å; F175-I179 HydrophobicContact CD1-CD1 3.77Å; F175-I179 HydrophobicContact CE1-CD1 3.36Å; F175-I179 HydrophobicContact CE1-CG1 4.39Å; F175-I179 HydrophobicContact CZ-CD1 3.94Å; F175-I179 PolarHBondContact O-N 3.32Å; F175-I179 VanDerWaalsContact O-N 3.13Å
176	I	94.9	Very high	91.9	Very high	8 Å²	8	23.6 Å²	23.6	4%	0.041	13%	0.126	C	C	.	.	H	α-helix	trans	-68.6	-33.4	177.7	-160.9	73.2	0	0	0	111.8	S172 M173 I178 I179 G180 I220 Y261	S172-I176 WeakPolarHBondContact O-CG2 3.31Å; S172-I176 PolarHBondContact O-N 2.86Å; M173-I176 VanDerWaalsContact O-CG2 3.23Å; M173-I176 WeakPolarHBondContact O-CG2 3.49Å; I176-I178 VanDerWaalsContact C-N 3.34Å; I176-I178 PolarHBondContact O-N 3.48Å; I176-I179 HydrophobicContact CD1-CD1 4.34Å; I176-I179 PolarHBondContact O-N 3.38Å; I176-G180 PolarHBondContact O-N 3.26Å; I176-I220 HydrophobicContact CB-CG2 4.21Å; I176-I220 HydrophobicContact CD1-CD1 4.22Å; I176-I220 HydrophobicContact CD1-CG2 4.45Å; I176-I220 HydrophobicContact CG1-CB 4.05Å; I176-I220 HydrophobicContact CG1-CG2 3.89Å; I176-I220 HydrophobicContact CG2-CG2 3.99Å; I176-Y261 HydrophobicContact CD1-CE1 4.27Å
177	N	94.2	Very high	91.9	Very high	1 Å²	1	23.1 Å²	23.1	1%	0.005	12%	0.123	C	C	.	.	H	α-helix	trans	-61.6	-41.7	173.7	-77.1	-17.1	0	0	0	111.7	M173 E174 F175 G180 C181 S221	M173-N177 VanDerWaalsContact O-CB 3.31Å; M173-N177 WeakPolarHBondContact O-CB 3.31Å; M173-N177 PolarHBondContact O-N 3.4Å; M173-N177 PolarHBondContact O-ND2 3.02Å; E174-N177 PolarHBondContact O-N 2.97Å; F175-N177 VanDerWaalsContact C-N 3.32Å; F175-N177 PolarHBondContact O-N 3.23Å; N177-G180 PolarHBondContact O-N 3.46Å; N177-C181 WeakPolarHBondContact O-CB 3.4Å; N177-C181 PolarHBondContact O-N 3.5Å; N177-S221 WeakPolarHBondContact OD1-CB 3.41Å; N177-S221 PolarHBondContact OD1-OG 3.42Å
178	I	95	Very high	91.9	Very high	32 Å²	32	22.7 Å²	22.7	16%	0.164	12%	0.121	C	C	.	.	H	α-helix	trans	-63.3	-44.6	175	-68.9	-63	0	0	0	111.1	H38 F42 E174 F175 I176 G180 C181 C182	H38-I178 HydrophobicContact CB-CD1 4.21Å; F42-I178 HydrophobicContact CB-CD1 3.8Å; F42-I178 HydrophobicContact CB-CG1 3.72Å; F42-I178 HydrophobicContact CD1-CG1 4.37Å; F42-I178 HydrophobicContact CD2-CG1 3.77Å; F42-I178 HydrophobicContact CG-CD1 4.22Å; F42-I178 HydrophobicContact CG-CG1 3.69Å; E174-I178 WeakPolarHBondContact O-CG1 3.4Å; E174-I178 PolarHBondContact O-N 3.3Å; F175-I178 PolarHBondContact O-N 3.49Å; I176-I178 VanDerWaalsContact C-N 3.34Å; I176-I178 PolarHBondContact O-N 3.48Å; I178-G180 PolarHBondContact O-N 2.93Å; I178-C181 WeakPolarHBondContact O-CB 3.27Å; I178-C181 PolarHBondContact O-N 3.43Å; I178-C182 WeakPolarHBondContact O-CB 3.23Å; I178-C182 PolarHBondContact O-N 3.11Å; I178-C182 PolarHBondContact O-SG 3.24Å
179	I	94.5	Very high	91.9	Very high	56 Å²	56	21.9 Å²	21.9	29%	0.287	12%	0.116	S	C	.	.	H	α-helix	trans	-58.3	-50.8	176.1	-68.5	170.2	0	0	0	110.4	F175 I176 C181 C182 T183 I213	F175-I179 HydrophobicContact CD1-CD1 3.77Å; F175-I179 HydrophobicContact CE1-CD1 3.36Å; F175-I179 HydrophobicContact CE1-CG1 4.39Å; F175-I179 HydrophobicContact CZ-CD1 3.94Å; F175-I179 PolarHBondContact O-N 3.32Å; F175-I179 VanDerWaalsContact O-N 3.13Å; I176-I179 HydrophobicContact CD1-CD1 4.34Å; I176-I179 PolarHBondContact O-N 3.38Å; I179-C181 VanDerWaalsContact C-N 3.34Å; I179-C181 PolarHBondContact O-N 3.46Å; I179-C182 PolarHBondContact O-N 3.43Å; I179-T183 PolarHBondContact O-N 3.46Å; I179-T183 PolarHBondContact O-OG1 2.99Å; I179-I213 HydrophobicContact CG2-CG2 3.35Å
180	G	92.7	Very high	91.7	Very high	0 Å²	0	25.6 Å²	25.6	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-60.7	-41.4	178.8	0	0	0	0	0	112.9	I176 N177 I178 C182 T183 D184 S217 W405	I176-G180 PolarHBondContact O-N 3.26Å; N177-G180 PolarHBondContact O-N 3.46Å; I178-G180 PolarHBondContact O-N 2.93Å; G180-C182 PolarHBondContact O-N 2.91Å; G180-T183 PolarHBondContact O-N 2.83Å; G180-T183 PolarHBondContact O-OG1 3.24Å; G180-T183 VanDerWaalsContact O-OG1 3.09Å; G180-D184 WeakPolarHBondContact O-CB 3.37Å; G180-D184 PolarHBondContact O-N 2.92Å; G180-S217 VanDerWaalsContact CA-CB 3.44Å; G180-S217 PolarHBondContact N-OG 3.03Å; G180-W405 VanDerWaalsContact C-CH2 3.47Å
181	C	92.7	Very high	91.5	Very high	2 Å²	2	25.4 Å²	25.4	1%	0.014	13%	0.129	C	C	.	.	I	π-helix	trans	-61.3	-43.2	175.7	-175.7	0	0	0	0	111.9	F35 N177 I178 I179 T183 L185 L186	F35-C181 WeakPolarHBondContact CD2-SG 3.36Å; N177-C181 WeakPolarHBondContact O-CB 3.4Å; N177-C181 PolarHBondContact O-N 3.5Å; I178-C181 WeakPolarHBondContact O-CB 3.27Å; I178-C181 PolarHBondContact O-N 3.43Å; I179-C181 VanDerWaalsContact C-N 3.34Å; I179-C181 PolarHBondContact O-N 3.46Å; C181-T183 VanDerWaalsContact C-N 3.32Å; C181-T183 PolarHBondContact O-N 3.02Å; C181-L185 WeakPolarHBondContact O-CB 3.48Å; C181-L185 PolarHBondContact O-N 3.38Å; C181-L185 VanDerWaalsContact SG-CD2 3.59Å; C181-L186 PolarHBondContact O-N 3.4Å
182	C	92.1	Very high	91.2	Very high	61 Å²	61	22.8 Å²	22.8	41%	0.412	12%	0.116	S	C	.	.	I	π-helix	trans	-66.8	-30.8	175.8	-71.2	0	0	0	0	113.1	I178 I179 G180 L186	I178-C182 WeakPolarHBondContact O-CB 3.23Å; I178-C182 PolarHBondContact O-N 3.11Å; I178-C182 PolarHBondContact O-SG 3.24Å; I179-C182 PolarHBondContact O-N 3.43Å; G180-C182 PolarHBondContact O-N 2.91Å; C182-L186 WeakPolarHBondContact O-CB 3.45Å
183	T	89.2	Confident	90.8	Very high	16 Å²	16	26.1 Å²	26.1	10%	0.098	13%	0.131	C	C	.	.	I	π-helix	trans	-90.7	-37.8	-178.8	55.3	0	0	0	0	114.6	I179 G180 C181 L210 I213	I179-T183 PolarHBondContact O-N 3.46Å; I179-T183 PolarHBondContact O-OG1 2.99Å; G180-T183 PolarHBondContact O-N 2.83Å; G180-T183 PolarHBondContact O-OG1 3.24Å; G180-T183 VanDerWaalsContact O-OG1 3.09Å; C181-T183 VanDerWaalsContact C-N 3.32Å; C181-T183 PolarHBondContact O-N 3.02Å; T183-L210 HydrophobicContact CG2-CD1 3.66Å; T183-I213 HydrophobicContact CG2-CB 4.1Å; T183-I213 HydrophobicContact CG2-CG2 3.56Å
184	D	88.4	Confident	90.3	Very high	0 Å²	0	28.9 Å²	28.9	0%	0	15%	0.148	C	C	.	.	I	π-helix	trans	-108.8	-57	-171.2	-169.1	38.5	0	0	0	112.3	G180 L186 R187 L188 S214 L384 W405	G180-D184 WeakPolarHBondContact O-CB 3.37Å; G180-D184 PolarHBondContact O-N 2.92Å; D184-L186 VanDerWaalsContact C-N 3.32Å; D184-L186 PolarHBondContact O-N 3.38Å; D184-R187 CarbonylContact O-C 3.57Å; D184-R187 WeakPolarHBondContact O-CA 3.49Å; D184-R187 WeakPolarHBondContact O-CB 3.16Å; D184-R187 PolarHBondContact O-N 3.35Å; D184-R187 IonicContact OD1-CZ 3.72Å; D184-R187 IonicContact OD1-NE 3.46Å; D184-R187 IonicContact OD1-NH2 3.6Å; D184-R187 PolarHBondContact OD1-NH2 3.27Å; D184-L188 WeakPolarHBondContact O-CG 3.29Å; D184-L188 PolarHBondContact O-N 3.48Å; D184-S214 WeakPolarHBondContact CB-OG 3.3Å; D184-L384 WeakPolarHBondContact OD2-CD2 3.25Å; D184-W405 HydrophobicContact CB-CZ2 3.84Å; D184-W405 PolarHBondContact OD2-NE1 2.97Å
185	L	90.8	Very high	89.5	Confident	0 Å²	0	29.6 Å²	29.6	0%	0	16%	0.156	C	C	.	.	I	π-helix	trans	-61.5	-42.2	-177.9	-176.7	61.3	0	0	0	111.5	F35 C181 R187 L188 I189 I402 W405	F35-L185 HydrophobicContact CB-CD2 3.93Å; C181-L185 WeakPolarHBondContact O-CB 3.48Å; C181-L185 PolarHBondContact O-N 3.38Å; C181-L185 VanDerWaalsContact SG-CD2 3.59Å; L185-R187 VanDerWaalsContact C-N 3.29Å; L185-R187 PolarHBondContact O-N 2.9Å; L185-L188 PolarHBondContact O-N 2.93Å; L185-I189 HydrophobicContact CD1-CD1 4.44Å; L185-I189 HydrophobicContact CD1-CG1 4.39Å; L185-I189 HydrophobicContact CG-CD1 3.95Å; L185-I189 HydrophobicContact CG-CG1 4.38Å; L185-I189 WeakPolarHBondContact O-CB 3.35Å; L185-I189 VanDerWaalsContact O-CG1 3.23Å; L185-I189 WeakPolarHBondContact O-CG1 3.31Å; L185-I189 PolarHBondContact O-N 2.86Å; L185-I402 HydrophobicContact CD1-CG1 3.98Å; L185-W405 HydrophobicContact CB-CD2 4.35Å; L185-W405 HydrophobicContact CB-CG 4.13Å; L185-W405 HydrophobicContact CD1-CB 4.07Å; L185-W405 HydrophobicContact CD1-CG 4.16Å; L185-W405 HydrophobicContact CD2-CB 4.17Å; L185-W405 HydrophobicContact CD2-CG 4.47Å; L185-W405 HydrophobicContact CG-CG 4.48Å
186	L	90.6	Very high	88.5	Confident	77 Å²	77	28 Å²	28	40%	0.403	15%	0.152	S	C	.	.	H	α-helix	trans	-60	-39.8	175	-174.6	63.8	0	0	0	112.1	C181 C182 D184 Y190	C181-L186 PolarHBondContact O-N 3.4Å; C182-L186 WeakPolarHBondContact O-CB 3.45Å; D184-L186 VanDerWaalsContact C-N 3.32Å; D184-L186 PolarHBondContact O-N 3.38Å; L186-Y190 WeakPolarHBondContact O-CB 3.38Å; L186-Y190 PolarHBondContact O-N 3.33Å
187	R	87.1	Confident	87.5	Confident	7 Å²	7	28 Å²	28	3%	0.026	15%	0.152	C	C	.	.	H	α-helix	trans	-64.6	-44.4	174.8	176.1	-173.1	68.5	103.6	2.3	111.1	D184 L185 Y190 L191 D197 L198 R199 L384	D184-R187 CarbonylContact O-C 3.57Å; D184-R187 WeakPolarHBondContact O-CA 3.49Å; D184-R187 WeakPolarHBondContact O-CB 3.16Å; D184-R187 PolarHBondContact O-N 3.35Å; D184-R187 IonicContact OD1-CZ 3.72Å; D184-R187 IonicContact OD1-NE 3.46Å; D184-R187 IonicContact OD1-NH2 3.6Å; D184-R187 PolarHBondContact OD1-NH2 3.27Å; L185-R187 VanDerWaalsContact C-N 3.29Å; L185-R187 PolarHBondContact O-N 2.9Å; R187-Y190 PolarHBondContact O-N 3.49Å; R187-L191 VanDerWaalsContact O-CB 3.31Å; R187-L191 WeakPolarHBondContact O-CB 3.48Å; R187-L191 PolarHBondContact O-N 3.32Å; R187-D197 WeakPolarHBondContact CD-OD1 3.11Å; R187-D197 IonicContact NH1-OD2 3.29Å; R187-D197 PolarHBondContact NH1-OD2 2.99Å; R187-L198 HydrophobicContact CG-CB 4.18Å; R187-R199 VanDerWaalsContact NH1-CZ 3.34Å; R187-L384 PolarHBondContact NH1-O 2.99Å; R187-L384 PolarHBondContact NH2-O 2.94Å
188	L	87.9	Confident	86.4	Confident	0 Å²	0	29.4 Å²	29.4	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-63.8	-42.8	177.4	-69.4	170.3	0	0	0	111.5	D184 L185 Y190 L191 S192 I402	D184-L188 WeakPolarHBondContact O-CG 3.29Å; D184-L188 PolarHBondContact O-N 3.48Å; L185-L188 PolarHBondContact O-N 2.93Å; L188-Y190 PolarHBondContact O-N 3.08Å; L188-L191 PolarHBondContact O-N 3.05Å; L188-S192 WeakPolarHBondContact O-CB 3.36Å; L188-S192 PolarHBondContact O-N 2.83Å; L188-S192 PolarHBondContact O-OG 3.21Å; L188-S192 VanDerWaalsContact O-OG 3.07Å; L188-I402 HydrophobicContact CB-CD1 4.28Å; L188-I402 HydrophobicContact CB-CG1 4.08Å; L188-I402 HydrophobicContact CD1-CG1 4.3Å
189	I	89.7	Confident	85	Confident	13 Å²	13	28.7 Å²	28.7	7%	0.067	16%	0.155	C	C	.	.	H	α-helix	trans	-58.5	-48.8	173.4	-68.9	162.9	0	0	0	110.2	G31 I32 F35 L185 L191 S192 I193	G31-I189 VanDerWaalsContact C-CD1 3.42Å; G31-I189 WeakPolarHBondContact O-CD1 3.3Å; I32-I189 HydrophobicContact CD1-CG2 4.36Å; I32-I189 HydrophobicContact CG1-CD1 4.33Å; I32-I189 HydrophobicContact CG1-CG2 3.78Å; F35-I189 HydrophobicContact CB-CD1 4Å; L185-I189 HydrophobicContact CD1-CD1 4.44Å; L185-I189 HydrophobicContact CD1-CG1 4.39Å; L185-I189 HydrophobicContact CG-CD1 3.95Å; L185-I189 HydrophobicContact CG-CG1 4.38Å; L185-I189 WeakPolarHBondContact O-CB 3.35Å; L185-I189 VanDerWaalsContact O-CG1 3.23Å; L185-I189 WeakPolarHBondContact O-CG1 3.31Å; L185-I189 PolarHBondContact O-N 2.86Å; I189-L191 VanDerWaalsContact C-N 3.35Å; I189-L191 PolarHBondContact O-N 3.08Å; I189-S192 PolarHBondContact O-N 2.91Å; I189-I193 HydrophobicContact CG2-CD1 3.66Å; I189-I193 HydrophobicContact CG2-CG1 4.47Å; I189-I193 WeakPolarHBondContact O-CG1 3.31Å; I189-I193 PolarHBondContact O-N 3.48Å
190	Y	88	Confident	83.6	Confident	77 Å²	77	31 Å²	31	30%	0.302	17%	0.167	S	C	.	.	H	α-helix	trans	-62.3	-42.8	179.5	-176.5	-95.3	0	0	0	112	L186 R187 L188 I193 T194 N196 L198 L201	L186-Y190 WeakPolarHBondContact O-CB 3.38Å; L186-Y190 PolarHBondContact O-N 3.33Å; R187-Y190 PolarHBondContact O-N 3.49Å; L188-Y190 PolarHBondContact O-N 3.08Å; Y190-I193 PolarHBondContact O-N 2.84Å; Y190-T194 HydrophobicContact CD2-CG2 3.96Å; Y190-T194 HydrophobicContact CE1-CG2 4.29Å; Y190-T194 WeakPolarHBondContact CE1-OG1 3.48Å; Y190-T194 HydrophobicContact CE2-CG2 3.6Å; Y190-T194 HydrophobicContact CG-CG2 4.44Å; Y190-T194 WeakPolarHBondContact O-CB 3.23Å; Y190-T194 PolarHBondContact O-N 2.92Å; Y190-T194 PolarHBondContact O-OG1 2.7Å; Y190-N196 VanDerWaalsContact CD1-O 3.25Å; Y190-N196 WeakPolarHBondContact CD1-O 3.24Å; Y190-N196 HydrophobicContact CE1-CB 4.48Å; Y190-N196 WeakPolarHBondContact CE1-O 3.34Å; Y190-L198 HydrophobicContact CD1-CB 3.78Å; Y190-L198 HydrophobicContact CD1-CD1 4.08Å; Y190-L198 HydrophobicContact CE1-CB 4.32Å; Y190-L198 HydrophobicContact CE1-CD1 4.17Å; Y190-L198 HydrophobicContact CG-CB 4.35Å; Y190-L198 HydrophobicContact CG-CD1 4.25Å; Y190-L201 HydrophobicContact CE1-CD1 4.13Å
191	L	85.1	Confident	82.4	Confident	0 Å²	0	36.2 Å²	36.2	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-63	-43.1	175.5	179.3	63.3	0	0	0	111.5	Q24 R187 L188 I189 G195 D197 A386 N389	Q24-L191 PolarHBondContact NE2-O 2.89Å; R187-L191 VanDerWaalsContact O-CB 3.31Å; R187-L191 WeakPolarHBondContact O-CB 3.48Å; R187-L191 PolarHBondContact O-N 3.32Å; L188-L191 PolarHBondContact O-N 3.05Å; I189-L191 VanDerWaalsContact C-N 3.35Å; I189-L191 PolarHBondContact O-N 3.08Å; L191-G195 WeakPolarHBondContact O-CA 3.49Å; L191-G195 PolarHBondContact O-N 2.89Å; L191-D197 HydrophobicContact CD1-CB 4.13Å; L191-A386 HydrophobicContact CD2-CB 4.21Å; L191-N389 HydrophobicContact CD1-CB 4.13Å; L191-N389 HydrophobicContact CG-CB 4.25Å
192	S	85.8	Confident	81.4	Confident	1 Å²	1	42.5 Å²	42.5	1%	0.007	22%	0.219	C	C	.	.	H	α-helix	trans	-63.4	-42.7	174.8	-67.8	0	0	0	0	111.3	Q24 L188 I189	Q24-S192 WeakPolarHBondContact CG-O 3.34Å; Q24-S192 PolarHBondContact NE2-O 3.46Å; L188-S192 WeakPolarHBondContact O-CB 3.36Å; L188-S192 PolarHBondContact O-N 2.83Å; L188-S192 PolarHBondContact O-OG 3.21Å; L188-S192 VanDerWaalsContact O-OG 3.07Å; I189-S192 PolarHBondContact O-N 2.91Å
193	I	85.7	Confident	80.6	Confident	86 Å²	86	41.3 Å²	41.3	44%	0.441	22%	0.217	S	C	.	.	H	α-helix	trans	-77.3	-43.3	-176.6	-65.7	169	0	0	0	112.3	I32 I189 Y190	I32-I193 HydrophobicContact CD1-CD1 4.08Å; I189-I193 HydrophobicContact CG2-CD1 3.66Å; I189-I193 HydrophobicContact CG2-CG1 4.47Å; I189-I193 WeakPolarHBondContact O-CG1 3.31Å; I189-I193 PolarHBondContact O-N 3.48Å; Y190-I193 PolarHBondContact O-N 2.84Å
194	T	84	Confident	79.8	Confident	59 Å²	59	43.8 Å²	43.8	36%	0.362	23%	0.227	S	C	.	.	H	α-helix	trans	-99.3	-20.1	-170.2	69.2	0	0	0	0	114	Y190 N196	Y190-T194 HydrophobicContact CD2-CG2 3.96Å; Y190-T194 HydrophobicContact CE1-CG2 4.29Å; Y190-T194 WeakPolarHBondContact CE1-OG1 3.48Å; Y190-T194 HydrophobicContact CE2-CG2 3.6Å; Y190-T194 HydrophobicContact CG-CG2 4.44Å; Y190-T194 WeakPolarHBondContact O-CB 3.23Å; Y190-T194 PolarHBondContact O-N 2.92Å; Y190-T194 PolarHBondContact O-OG1 2.7Å; T194-N196 PolarHBondContact O-N 3.25Å; T194-N196 PolarHBondContact OG1-N 3.46Å; T194-N196 PolarHBondContact OG1-O 3.24Å
195	G	76.7	Confident	79.5	Confident	15 Å²	15	51.3 Å²	51.3	16%	0.155	26%	0.256	C	S	.	.	S	Bend	trans	74	-1.6	-171.3	0	0	0	0	0	114.4	L191	L191-G195 WeakPolarHBondContact O-CA 3.49Å; L191-G195 PolarHBondContact O-N 2.89Å
196	N	74	Confident	79.1	Confident	78 Å²	78	56.2 Å²	56.2	42%	0.417	28%	0.279	S	S	.	.	S	Bend	trans	-107.4	137.5	176.7	-66.5	-20.7	0	0	0	109.5	Y190 T194 L198	Y190-N196 VanDerWaalsContact CD1-O 3.25Å; Y190-N196 WeakPolarHBondContact CD1-O 3.24Å; Y190-N196 HydrophobicContact CE1-CB 4.48Å; Y190-N196 WeakPolarHBondContact CE1-O 3.34Å; T194-N196 PolarHBondContact O-N 3.25Å; T194-N196 PolarHBondContact OG1-N 3.46Å; T194-N196 PolarHBondContact OG1-O 3.24Å; N196-L198 PolarHBondContact O-N 3.49Å
197	D	72.6	Confident	78.5	Confident	6 Å²	6	52.9 Å²	52.9	3%	0.032	26%	0.262	C	S	.	.			trans	-77.3	127.9	175.4	-163.6	-44.8	0	0	0	110.2	R187 L191 R199 L200	R187-D197 WeakPolarHBondContact CD-OD1 3.11Å; R187-D197 IonicContact NH1-OD2 3.29Å; R187-D197 PolarHBondContact NH1-OD2 2.99Å; L191-D197 HydrophobicContact CD1-CB 4.13Å; D197-R199 PolarHBondContact O-N 2.79Å; D197-R199 VanDerWaalsContact O-N 3.07Å; D197-R199 VanDerWaalsContact OD1-CB 3.3Å; D197-R199 WeakPolarHBondContact OD1-CB 3.35Å; D197-R199 VanDerWaalsContact OD1-CG 3.25Å; D197-R199 WeakPolarHBondContact OD1-CG 3.31Å; D197-R199 PolarHBondContact OD1-N 2.88Å; D197-R199 IonicContact OD1-NE 3.1Å; D197-R199 PolarHBondContact OD1-NE 3.47Å; D197-R199 VanDerWaalsContact OD1-NE 3.1Å; D197-R199 IonicContact OD2-CZ 3.12Å; D197-R199 IonicContact OD2-NE 2.83Å; D197-R199 PolarHBondContact OD2-NE 2.96Å; D197-R199 IonicContact OD2-NH2 2.64Å; D197-R199 PolarHBondContact OD2-NH2 3.02Å; D197-L200 HydrophobicContact CB-CD1 4.37Å; D197-L200 HydrophobicContact CB-CG 4.36Å; D197-L200 WeakPolarHBondContact O-CB 3.5Å; D197-L200 PolarHBondContact O-N 2.91Å
198	L	70.7	Confident	78.1	Confident	31 Å²	31	53.1 Å²	53.1	16%	0.162	26%	0.263	C	S	.	.	G	3₁₀ helix	trans	-53.9	-28.2	177.4	-171.3	67.4	0	0	0	111.9	R187 Y190 N196 L200 L201 Y202	R187-L198 HydrophobicContact CG-CB 4.18Å; Y190-L198 HydrophobicContact CD1-CB 3.78Å; Y190-L198 HydrophobicContact CD1-CD1 4.08Å; Y190-L198 HydrophobicContact CE1-CB 4.32Å; Y190-L198 HydrophobicContact CE1-CD1 4.17Å; Y190-L198 HydrophobicContact CG-CB 4.35Å; Y190-L198 HydrophobicContact CG-CD1 4.25Å; N196-L198 PolarHBondContact O-N 3.49Å; L198-L200 VanDerWaalsContact C-N 3.26Å; L198-L200 PolarHBondContact O-N 3.31Å; L198-L201 HydrophobicContact CD1-CD1 4.01Å; L198-L201 WeakPolarHBondContact O-CB 3.49Å; L198-L201 PolarHBondContact O-N 3.09Å; L198-L201 VanDerWaalsContact O-N 3.16Å; L198-Y202 HydrophobicContact CD1-CE2 4.03Å; L198-Y202 HydrophobicContact CG-CD2 4.5Å; L198-Y202 HydrophobicContact CG-CE2 3.91Å; L198-Y202 VanDerWaalsContact O-CD2 3.32Å; L198-Y202 WeakPolarHBondContact O-CD2 3.48Å
199	R	66.4	Low	78.1	Confident	18 Å²	18	56.8 Å²	56.8	7%	0.068	28%	0.282	C	S	.	.	G	3₁₀ helix	trans	-61.1	-31.6	177.1	-69	177.7	-60.6	162.3	0.9	113.8	R187 D197 L201 Y202 C207 L210 I385	R187-R199 VanDerWaalsContact NH1-CZ 3.34Å; D197-R199 PolarHBondContact O-N 2.79Å; D197-R199 VanDerWaalsContact O-N 3.07Å; D197-R199 VanDerWaalsContact OD1-CB 3.3Å; D197-R199 WeakPolarHBondContact OD1-CB 3.35Å; D197-R199 VanDerWaalsContact OD1-CG 3.25Å; D197-R199 WeakPolarHBondContact OD1-CG 3.31Å; D197-R199 PolarHBondContact OD1-N 2.88Å; D197-R199 IonicContact OD1-NE 3.1Å; D197-R199 PolarHBondContact OD1-NE 3.47Å; D197-R199 VanDerWaalsContact OD1-NE 3.1Å; D197-R199 IonicContact OD2-CZ 3.12Å; D197-R199 IonicContact OD2-NE 2.83Å; D197-R199 PolarHBondContact OD2-NE 2.96Å; D197-R199 IonicContact OD2-NH2 2.64Å; D197-R199 PolarHBondContact OD2-NH2 3.02Å; R199-L201 PolarHBondContact O-N 3.18Å; R199-Y202 PolarHBondContact O-N 3.08Å; R199-C207 HydrophobicContact CB-CB 4.43Å; R199-L210 HydrophobicContact CG-CD2 4.05Å; R199-I385 VanDerWaalsContact NH1-CD1 3.31Å
200	L	64.8	Low	77.9	Confident	103 Å²	103	57.9 Å²	57.9	54%	0.539	29%	0.288	S	S	.	.	G	3₁₀ helix	trans	-71.7	-14.2	-179.4	-63	172.8	0	0	0	112.4	D197 L198 Y279	D197-L200 HydrophobicContact CB-CD1 4.37Å; D197-L200 HydrophobicContact CB-CG 4.36Å; D197-L200 WeakPolarHBondContact O-CB 3.5Å; D197-L200 PolarHBondContact O-N 2.91Å; L198-L200 VanDerWaalsContact C-N 3.26Å; L198-L200 PolarHBondContact O-N 3.31Å; L200-Y279 HydrophobicContact CD2-CD1 4.28Å; L200-Y279 HydrophobicContact CD2-CE1 3.65Å
201	L	68.8	Low	77.6	Confident	110 Å²	110	55 Å²	55	58%	0.576	28%	0.277	S	S	*	.	G	3₁₀ helix	trans	-86.7	-14.9	178.7	-64.5	170.1	0	0	0	112.8	Y190 L198 R199	Y190-L201 HydrophobicContact CE1-CD1 4.13Å; L198-L201 HydrophobicContact CD1-CD1 4.01Å; L198-L201 WeakPolarHBondContact O-CB 3.49Å; L198-L201 PolarHBondContact O-N 3.09Å; L198-L201 VanDerWaalsContact O-N 3.16Å; R199-L201 PolarHBondContact O-N 3.18Å
202	Y	71.4	Confident	77.7	Confident	134 Å²	134	56.7 Å²	56.7	53%	0.525	29%	0.285	S	S	.	.	S	Bend	trans	-116.2	158	-178.1	-60.9	-74.6	0	0	0	111.1	L198 R199	L198-Y202 HydrophobicContact CD1-CE2 4.03Å; L198-Y202 HydrophobicContact CG-CD2 4.5Å; L198-Y202 HydrophobicContact CG-CE2 3.91Å; L198-Y202 VanDerWaalsContact O-CD2 3.32Å; L198-Y202 WeakPolarHBondContact O-CD2 3.48Å; R199-Y202 PolarHBondContact O-N 3.08Å
203	G	74.5	Confident	78	Confident	36 Å²	36	59.1 Å²	59.1	37%	0.371	30%	0.297	S	S	.	.			trans	-60.4	162.3	177.5	0	0	0	0	0	113.3	W205 Q206 C207	G203-W205 VanDerWaalsContact C-N 3.26Å; G203-W205 PolarHBondContact O-N 3.01Å; G203-Q206 VanDerWaalsContact C-OE1 3.24Å; G203-Q206 PolarHBondContact O-N 3.49Å; G203-Q206 VanDerWaalsContact O-N 3.16Å; G203-Q206 PolarHBondContact O-OE1 2.86Å; G203-C207 PolarHBondContact O-N 3.28Å
204	E	73.5	Confident	78.2	Confident	69 Å²	69	55.2 Å²	55.2	32%	0.322	28%	0.277	S	S	.	.	H	α-helix	trans	-56.8	-38.2	-175.1	-172.6	179.4	175.1	0	0	112.9	C207 R208 Y279	E204-C207 WeakPolarHBondContact O-CB 3.14Å; E204-C207 PolarHBondContact O-N 2.93Å; E204-R208 WeakPolarHBondContact O-CG 3.5Å; E204-R208 PolarHBondContact O-N 2.99Å; E204-R208 IonicContact OE1-CZ 3.6Å; E204-R208 IonicContact OE1-NE 2.72Å; E204-R208 PolarHBondContact OE1-NE 3.13Å; E204-R208 IonicContact OE1-NH2 3.32Å; E204-R208 PolarHBondContact OE1-NH2 3.31Å; E204-Y279 HydrophobicContact CB-CE2 4.28Å; E204-Y279 HydrophobicContact CG-CE2 4.35Å
205	W	80.3	Confident	78.3	Confident	157 Å²	157	52.9 Å²	52.9	60%	0.595	26%	0.262	S	S	*	.	H	α-helix	trans	-67.8	-42.2	179.6	-173.4	-103.7	0	0	0	112.6	G203 C207 R208 L209	G203-W205 VanDerWaalsContact C-N 3.26Å; G203-W205 PolarHBondContact O-N 3.01Å; W205-C207 VanDerWaalsContact C-N 3.29Å; W205-C207 PolarHBondContact O-N 2.87Å; W205-R208 WeakPolarHBondContact O-CB 3.18Å; W205-R208 PolarHBondContact O-N 3.17Å; W205-L209 WeakPolarHBondContact O-CB 3.44Å; W205-L209 PolarHBondContact O-N 3.47Å
206	Q	82.6	Confident	79.1	Confident	104 Å²	104	52.9 Å²	52.9	49%	0.486	26%	0.259	S	S	.	.	H	α-helix	trans	-64.1	-38.9	176.3	-65.8	84	-8.7	0	0	110.6	G203 L209 L210	G203-Q206 VanDerWaalsContact C-OE1 3.24Å; G203-Q206 PolarHBondContact O-N 3.49Å; G203-Q206 VanDerWaalsContact O-N 3.16Å; G203-Q206 PolarHBondContact O-OE1 2.86Å; Q206-L209 PolarHBondContact O-N 3.43Å; Q206-L210 VanDerWaalsContact O-CB 3.31Å; Q206-L210 WeakPolarHBondContact O-CB 3.38Å; Q206-L210 PolarHBondContact O-N 2.97Å
207	C	78.7	Confident	80	Confident	7 Å²	7	49.2 Å²	49.2	5%	0.047	24%	0.239	C	C	.	.	H	α-helix	trans	-60.9	-47.7	173.8	177.2	0	0	0	0	111.8	R199 G203 E204 W205 L209 L210 I211	R199-C207 HydrophobicContact CB-CB 4.43Å; G203-C207 PolarHBondContact O-N 3.28Å; E204-C207 WeakPolarHBondContact O-CB 3.14Å; E204-C207 PolarHBondContact O-N 2.93Å; W205-C207 VanDerWaalsContact C-N 3.29Å; W205-C207 PolarHBondContact O-N 2.87Å; C207-L209 PolarHBondContact O-N 3.48Å; C207-L210 PolarHBondContact O-N 2.73Å; C207-I211 VanDerWaalsContact O-CG1 3.31Å; C207-I211 WeakPolarHBondContact O-CG1 3.26Å; C207-I211 PolarHBondContact O-N 3.21Å
208	R	79.1	Confident	80.8	Confident	11 Å²	11	49.6 Å²	49.6	4%	0.042	24%	0.242	C	C	.	.	H	α-helix	trans	-56.3	-49.1	175.1	-75.6	167.9	-175.9	-99.5	-1.3	112	E204 W205 L210 I211 F212 L272 I273 Y276 I278	E204-R208 WeakPolarHBondContact O-CG 3.5Å; E204-R208 PolarHBondContact O-N 2.99Å; E204-R208 IonicContact OE1-CZ 3.6Å; E204-R208 IonicContact OE1-NE 2.72Å; E204-R208 PolarHBondContact OE1-NE 3.13Å; E204-R208 IonicContact OE1-NH2 3.32Å; E204-R208 PolarHBondContact OE1-NH2 3.31Å; W205-R208 WeakPolarHBondContact O-CB 3.18Å; W205-R208 PolarHBondContact O-N 3.17Å; R208-L210 PolarHBondContact O-N 3.24Å; R208-I211 PolarHBondContact O-N 3.48Å; R208-F212 VanDerWaalsContact O-CB 3.3Å; R208-F212 WeakPolarHBondContact O-CB 3.46Å; R208-F212 PolarHBondContact O-N 2.82Å; R208-L272 HydrophobicContact CB-CD2 4.4Å; R208-L272 PolarHBondContact NH1-O 3.11Å; R208-I273 PolarHBondContact NH1-O 3.21Å; R208-Y276 PolarHBondContact NH2-O 2.88Å; R208-I278 HydrophobicContact CB-CD1 4.4Å; R208-I278 HydrophobicContact CG-CD1 3.13Å
209	L	86.8	Confident	81.8	Confident	78 Å²	78	48.6 Å²	48.6	41%	0.408	24%	0.237	S	C	.	.	H	α-helix	trans	-64.2	-40.9	-179.2	-175.7	147.3	0	0	0	111.5	W205 Q206 C207 F212 I213	W205-L209 WeakPolarHBondContact O-CB 3.44Å; W205-L209 PolarHBondContact O-N 3.47Å; Q206-L209 PolarHBondContact O-N 3.43Å; C207-L209 PolarHBondContact O-N 3.48Å; L209-F212 PolarHBondContact O-N 3.47Å; L209-I213 HydrophobicContact CD2-CD1 3.41Å; L209-I213 VanDerWaalsContact CD2-CD1 3.41Å; L209-I213 HydrophobicContact CD2-CG1 4.29Å; L209-I213 HydrophobicContact CG-CD1 4.16Å; L209-I213 VanDerWaalsContact O-CG1 3.3Å; L209-I213 WeakPolarHBondContact O-CG1 3.36Å; L209-I213 PolarHBondContact O-N 3.12Å
210	L	86.4	Confident	83.1	Confident	36 Å²	36	47.8 Å²	47.8	19%	0.188	23%	0.234	C	C	.	.	H	α-helix	trans	-61.4	-46.3	176.4	-170.6	73	0	0	0	111.7	T183 R199 Q206 C207 R208 I213 S214	T183-L210 HydrophobicContact CG2-CD1 3.66Å; R199-L210 HydrophobicContact CG-CD2 4.05Å; Q206-L210 VanDerWaalsContact O-CB 3.31Å; Q206-L210 WeakPolarHBondContact O-CB 3.38Å; Q206-L210 PolarHBondContact O-N 2.97Å; C207-L210 PolarHBondContact O-N 2.73Å; R208-L210 PolarHBondContact O-N 3.24Å; L210-I213 PolarHBondContact O-N 3.33Å; L210-S214 WeakPolarHBondContact O-CB 3.47Å; L210-S214 PolarHBondContact O-N 3.02Å
211	I	81.4	Confident	84.4	Confident	16 Å²	16	42.9 Å²	42.9	8%	0.082	21%	0.208	C	C	.	.	H	α-helix	trans	-63.7	-45.4	177.4	-66.2	165.2	0	0	0	110.2	C207 R208 I213 S214 F215 L271 I385	C207-I211 VanDerWaalsContact O-CG1 3.31Å; C207-I211 WeakPolarHBondContact O-CG1 3.26Å; C207-I211 PolarHBondContact O-N 3.21Å; R208-I211 PolarHBondContact O-N 3.48Å; I211-I213 PolarHBondContact O-N 3.24Å; I211-S214 PolarHBondContact O-N 3.19Å; I211-F215 HydrophobicContact CG2-CD2 3.77Å; I211-F215 HydrophobicContact CG2-CE2 4.04Å; I211-F215 WeakPolarHBondContact O-CD2 3.06Å; I211-F215 PolarHBondContact O-N 2.85Å; I211-L271 HydrophobicContact CG2-CD1 4.44Å; I211-I385 HydrophobicContact CD1-CD1 4.01Å
212	F	88.4	Confident	85.5	Confident	35 Å²	35	38 Å²	38	15%	0.154	18%	0.183	C	C	.	.	H	α-helix	trans	-59	-47.2	178.3	174.9	-103.8	0	0	0	112.3	R208 L209 F215 I216 N268 L271 L272	R208-F212 VanDerWaalsContact O-CB 3.3Å; R208-F212 WeakPolarHBondContact O-CB 3.46Å; R208-F212 PolarHBondContact O-N 2.82Å; L209-F212 PolarHBondContact O-N 3.47Å; F212-F215 PolarHBondContact O-N 3.44Å; F212-I216 HydrophobicContact CD1-CD1 3.85Å; F212-I216 HydrophobicContact CD2-CD1 3.87Å; F212-I216 HydrophobicContact CE1-CD1 3.32Å; F212-I216 HydrophobicContact CE2-CD1 3.35Å; F212-I216 HydrophobicContact CE2-CG1 4.28Å; F212-I216 HydrophobicContact CG-CD1 4.12Å; F212-I216 HydrophobicContact CZ-CD1 3.07Å; F212-I216 HydrophobicContact CZ-CG1 4.37Å; F212-I216 WeakPolarHBondContact O-CB 3.46Å; F212-I216 WeakPolarHBondContact O-CG1 3.41Å; F212-I216 PolarHBondContact O-N 3.21Å; F212-N268 HydrophobicContact CD2-CB 4.24Å; F212-N268 WeakPolarHBondContact CD2-O 3.38Å; F212-N268 HydrophobicContact CE2-CB 4.19Å; F212-L271 HydrophobicContact CD2-CB 4.47Å; F212-L272 HydrophobicContact CB-CD2 3.72Å; F212-L272 HydrophobicContact CB-CG 4.17Å; F212-L272 HydrophobicContact CD1-CD1 4.03Å; F212-L272 HydrophobicContact CD1-CD2 4.22Å; F212-L272 HydrophobicContact CD1-CG 4.32Å; F212-L272 HydrophobicContact CD2-CD1 3.91Å; F212-L272 HydrophobicContact CD2-CD2 4.24Å; F212-L272 HydrophobicContact CD2-CG 3.73Å; F212-L272 HydrophobicContact CE1-CD1 3.91Å; F212-L272 HydrophobicContact CE2-CD1 3.79Å; F212-L272 HydrophobicContact CE2-CG 4.08Å; F212-L272 HydrophobicContact CG-CD1 4Å; F212-L272 HydrophobicContact CG-CD2 3.83Å; F212-L272 HydrophobicContact CG-CG 3.83Å; F212-L272 HydrophobicContact CZ-CD1 3.76Å; F212-L272 HydrophobicContact CZ-CG 4.5Å
213	I	91.6	Very high	86.6	Confident	52 Å²	52	34.4 Å²	34.4	27%	0.267	17%	0.168	S	C	.	.	H	α-helix	trans	-63.7	-43.3	177.8	-69	175.1	0	0	0	111	I179 T183 L209 L210 I211 F215 S217	I179-I213 HydrophobicContact CG2-CG2 3.35Å; T183-I213 HydrophobicContact CG2-CB 4.1Å; T183-I213 HydrophobicContact CG2-CG2 3.56Å; L209-I213 HydrophobicContact CD2-CD1 3.41Å; L209-I213 VanDerWaalsContact CD2-CD1 3.41Å; L209-I213 HydrophobicContact CD2-CG1 4.29Å; L209-I213 HydrophobicContact CG-CD1 4.16Å; L209-I213 VanDerWaalsContact O-CG1 3.3Å; L209-I213 WeakPolarHBondContact O-CG1 3.36Å; L209-I213 PolarHBondContact O-N 3.12Å; L210-I213 PolarHBondContact O-N 3.33Å; I211-I213 PolarHBondContact O-N 3.24Å; I213-F215 VanDerWaalsContact C-N 3.34Å; I213-F215 PolarHBondContact O-N 3.35Å; I213-S217 VanDerWaalsContact O-CB 3.27Å; I213-S217 WeakPolarHBondContact O-CB 3.31Å; I213-S217 PolarHBondContact O-N 2.97Å; I213-S217 PolarHBondContact O-OG 3.13Å
214	S	89.1	Confident	87.5	Confident	4 Å²	4	32.7 Å²	32.7	3%	0.028	15%	0.15	C	C	.	.	H	α-helix	trans	-57	-48.8	176.1	161.4	0	0	0	0	111.3	D184 L210 I211 S217 C218 L384	D184-S214 WeakPolarHBondContact CB-OG 3.3Å; L210-S214 WeakPolarHBondContact O-CB 3.47Å; L210-S214 PolarHBondContact O-N 3.02Å; I211-S214 PolarHBondContact O-N 3.19Å; S214-S217 PolarHBondContact O-N 3.39Å; S214-C218 PolarHBondContact O-N 2.93Å; S214-C218 VanDerWaalsContact O-N 3.09Å; S214-C218 PolarHBondContact O-SG 3.2Å; S214-C218 VanDerWaalsContact O-SG 3.37Å; S214-L384 VanDerWaalsContact OG-CD1 3.27Å; S214-L384 WeakPolarHBondContact OG-CD1 3.4Å
215	F	87	Confident	88.4	Confident	10 Å²	10	30 Å²	30	4%	0.044	14%	0.138	C	C	.	.	H	α-helix	trans	-62.2	-49.6	-179.5	-100.1	-75.1	0	0	0	113.4	I211 F212 I213 S217 C218 D219 L271 C382 F383 L384	I211-F215 HydrophobicContact CG2-CD2 3.77Å; I211-F215 HydrophobicContact CG2-CE2 4.04Å; I211-F215 WeakPolarHBondContact O-CD2 3.06Å; I211-F215 PolarHBondContact O-N 2.85Å; F212-F215 PolarHBondContact O-N 3.44Å; I213-F215 VanDerWaalsContact C-N 3.34Å; I213-F215 PolarHBondContact O-N 3.35Å; F215-S217 PolarHBondContact O-N 3.24Å; F215-C218 PolarHBondContact O-N 3.37Å; F215-D219 PolarHBondContact O-N 3.08Å; F215-L271 HydrophobicContact CB-CD1 3.81Å; F215-L271 HydrophobicContact CD1-CD1 4.5Å; F215-L271 HydrophobicContact CD2-CD1 3.63Å; F215-L271 HydrophobicContact CE2-CD1 4.4Å; F215-L271 HydrophobicContact CG-CD1 3.68Å; F215-C382 HydrophobicContact CE2-CB 3.66Å; F215-C382 VanDerWaalsContact CE2-O 3.23Å; F215-C382 WeakPolarHBondContact CE2-O 3.21Å; F215-C382 HydrophobicContact CZ-CB 3.6Å; F215-C382 WeakPolarHBondContact CZ-O 3.4Å; F215-F383 HydrophobicContact CE1-CB 4.38Å; F215-F383 AromaticContact CE1-CD2 3.83Å; F215-F383 HydrophobicContact CE1-CD2 3.83Å; F215-F383 HydrophobicContact CZ-CB 4.02Å; F215-F383 AromaticContact CZ-CD2 3.92Å; F215-F383 HydrophobicContact CZ-CD2 3.92Å; F215-F383 HydrophobicContact CZ-CG 4.48Å; F215-L384 HydrophobicContact CE2-CD1 4.28Å; F215-L384 HydrophobicContact CZ-CD1 4.46Å
216	I	92.5	Very high	89	Confident	15 Å²	15	22.6 Å²	22.6	8%	0.077	11%	0.11	C	C	.	.	H	α-helix	trans	-60.6	-38.4	177.4	-74.5	176.5	0	0	0	110.2	F212 C218 D219 I220 N268	F212-I216 HydrophobicContact CD1-CD1 3.85Å; F212-I216 HydrophobicContact CD2-CD1 3.87Å; F212-I216 HydrophobicContact CE1-CD1 3.32Å; F212-I216 HydrophobicContact CE2-CD1 3.35Å; F212-I216 HydrophobicContact CE2-CG1 4.28Å; F212-I216 HydrophobicContact CG-CD1 4.12Å; F212-I216 HydrophobicContact CZ-CD1 3.07Å; F212-I216 HydrophobicContact CZ-CG1 4.37Å; F212-I216 WeakPolarHBondContact O-CB 3.46Å; F212-I216 WeakPolarHBondContact O-CG1 3.41Å; F212-I216 PolarHBondContact O-N 3.21Å; I216-C218 PolarHBondContact O-N 2.92Å; I216-D219 PolarHBondContact O-N 3.37Å; I216-I220 HydrophobicContact CG2-CD1 3.26Å; I216-I220 HydrophobicContact CG2-CG1 3.88Å; I216-I220 WeakPolarHBondContact O-CB 3.25Å; I216-I220 WeakPolarHBondContact O-CG1 3.32Å; I216-I220 PolarHBondContact O-N 2.71Å; I216-N268 HydrophobicContact CD1-CB 4.45Å; I216-N268 HydrophobicContact CG1-CB 3.91Å
217	S	93.3	Very high	89.5	Confident	2 Å²	2	19.4 Å²	19.4	1%	0.014	9%	0.094	C	C	.	.	H	α-helix	trans	-64.2	-42.3	-179.1	-59.2	0	0	0	0	112.3	G180 I213 S214 F215 S221	G180-S217 VanDerWaalsContact CA-CB 3.44Å; G180-S217 PolarHBondContact N-OG 3.03Å; I213-S217 VanDerWaalsContact O-CB 3.27Å; I213-S217 WeakPolarHBondContact O-CB 3.31Å; I213-S217 PolarHBondContact O-N 2.97Å; I213-S217 PolarHBondContact O-OG 3.13Å; S214-S217 PolarHBondContact O-N 3.39Å; F215-S217 PolarHBondContact O-N 3.24Å; S217-S221 WeakPolarHBondContact O-CB 3.47Å; S217-S221 PolarHBondContact O-N 2.87Å
218	C	89.6	Confident	90	Very high	14 Å²	14	19.1 Å²	19.1	10%	0.095	9%	0.092	C	C	.	.	H	α-helix	trans	-63.7	-51.5	174.9	-64.1	0	0	0	0	111.7	S214 F215 I216 I220 S221 E222	S214-C218 PolarHBondContact O-N 2.93Å; S214-C218 VanDerWaalsContact O-N 3.09Å; S214-C218 PolarHBondContact O-SG 3.2Å; S214-C218 VanDerWaalsContact O-SG 3.37Å; F215-C218 PolarHBondContact O-N 3.37Å; I216-C218 PolarHBondContact O-N 2.92Å; C218-I220 PolarHBondContact O-N 3.36Å; C218-S221 PolarHBondContact O-N 3.42Å; C218-E222 PolarHBondContact O-N 3.4Å
219	D	91.4	Very high	90.5	Very high	10 Å²	10	18.8 Å²	18.8	5%	0.053	9%	0.091	C	C	.	.	H	α-helix	trans	-59.1	-49.3	-179.3	-74.6	6.8	0	0	0	110.9	F215 I216 S221 E222 W223 N268 T296	F215-D219 PolarHBondContact O-N 3.08Å; I216-D219 PolarHBondContact O-N 3.37Å; D219-S221 PolarHBondContact O-N 3.46Å; D219-E222 PolarHBondContact O-N 2.94Å; D219-W223 PolarHBondContact O-N 3.5Å; D219-N268 PolarHBondContact OD2-ND2 3.32Å; D219-T296 WeakPolarHBondContact OD1-CG2 3.47Å
220	I	94.2	Very high	90.7	Very high	0 Å²	0	18.6 Å²	18.6	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-61.9	-45	180	-71.5	-178.5	0	0	0	110.2	I176 I216 C218 E222 W223 H224 I260 Y261 S264	I176-I220 HydrophobicContact CB-CG2 4.21Å; I176-I220 HydrophobicContact CD1-CD1 4.22Å; I176-I220 HydrophobicContact CD1-CG2 4.45Å; I176-I220 HydrophobicContact CG1-CB 4.05Å; I176-I220 HydrophobicContact CG1-CG2 3.89Å; I176-I220 HydrophobicContact CG2-CG2 3.99Å; I216-I220 HydrophobicContact CG2-CD1 3.26Å; I216-I220 HydrophobicContact CG2-CG1 3.88Å; I216-I220 WeakPolarHBondContact O-CB 3.25Å; I216-I220 WeakPolarHBondContact O-CG1 3.32Å; I216-I220 PolarHBondContact O-N 2.71Å; C218-I220 PolarHBondContact O-N 3.36Å; I220-E222 VanDerWaalsContact C-N 3.34Å; I220-E222 PolarHBondContact O-N 3.46Å; I220-W223 PolarHBondContact O-N 3.27Å; I220-H224 WeakPolarHBondContact CG2-CE1 3.46Å; I220-H224 VanDerWaalsContact CG2-ND1 3.26Å; I220-H224 WeakPolarHBondContact CG2-ND1 3.39Å; I220-H224 PolarHBondContact O-N 3.1Å; I220-H224 PolarHBondContact O-ND1 3.32Å; I220-I260 HydrophobicContact CG1-CG2 4.41Å; I220-I260 HydrophobicContact CG2-CG2 4.35Å; I220-Y261 HydrophobicContact CD1-CD1 3.49Å; I220-Y261 VanDerWaalsContact CD1-CD1 3.49Å; I220-Y261 HydrophobicContact CD1-CD2 4.07Å; I220-Y261 HydrophobicContact CD1-CE1 3.77Å; I220-Y261 HydrophobicContact CD1-CE2 4.38Å; I220-Y261 HydrophobicContact CD1-CG 3.65Å; I220-Y261 HydrophobicContact CG2-CD2 4.07Å; I220-Y261 HydrophobicContact CG2-CE2 3.75Å; I220-S264 VanDerWaalsContact CG1-CB 3.47Å
221	S	92.8	Very high	90.8	Very high	0 Å²	0	17.3 Å²	17.3	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-59.6	-44.6	178.9	-174.6	0	0	0	0	112	N177 S217 C218 D219 H224 F225	N177-S221 WeakPolarHBondContact OD1-CB 3.41Å; N177-S221 PolarHBondContact OD1-OG 3.42Å; S217-S221 WeakPolarHBondContact O-CB 3.47Å; S217-S221 PolarHBondContact O-N 2.87Å; C218-S221 PolarHBondContact O-N 3.42Å; D219-S221 PolarHBondContact O-N 3.46Å; S221-H224 WeakPolarHBondContact O-CB 3.29Å; S221-H224 PolarHBondContact O-N 3.36Å; S221-F225 PolarHBondContact O-N 2.93Å
222	E	91.1	Very high	91	Very high	8 Å²	8	18.8 Å²	18.8	4%	0.037	9%	0.087	C	C	.	.	H	α-helix	trans	-60.4	-48.2	176.6	178.5	170.7	-149.7	0	0	112	C218 D219 I220 H224 F225 V226 T296 P300 Y363	C218-E222 PolarHBondContact O-N 3.4Å; D219-E222 PolarHBondContact O-N 2.94Å; I220-E222 VanDerWaalsContact C-N 3.34Å; I220-E222 PolarHBondContact O-N 3.46Å; E222-H224 VanDerWaalsContact C-N 3.31Å; E222-H224 PolarHBondContact O-N 3.18Å; E222-F225 WeakPolarHBondContact O-CB 3.31Å; E222-F225 PolarHBondContact O-N 3.2Å; E222-F225 VanDerWaalsContact O-N 3.1Å; E222-V226 HydrophobicContact CG-CG2 4.5Å; E222-V226 VanDerWaalsContact O-CG2 3.24Å; E222-V226 WeakPolarHBondContact O-CG2 3.28Å; E222-V226 PolarHBondContact O-N 2.85Å; E222-T296 VanDerWaalsContact CD-O 3.23Å; E222-T296 WeakPolarHBondContact OE2-CA 3.24Å; E222-P300 HydrophobicContact CG-CB 3.91Å; E222-P300 HydrophobicContact CG-CG 4.27Å; E222-P300 VanDerWaalsContact OE1-CB 3.26Å; E222-P300 WeakPolarHBondContact OE1-CB 3.37Å; E222-Y363 HydrophobicContact CG-CE1 4.38Å
223	W	94.2	Very high	91	Very high	58 Å²	58	17.6 Å²	17.6	22%	0.22	8%	0.083	C	C	.	.	H	α-helix	trans	-66.1	-32.2	178.7	-78.4	108.1	0	0	0	112.7	D219 I220 V226 Y227 I260 I295 I299 P300	D219-W223 PolarHBondContact O-N 3.5Å; I220-W223 PolarHBondContact O-N 3.27Å; W223-V226 HydrophobicContact CE3-CB 4.47Å; W223-V226 HydrophobicContact CE3-CG1 4.43Å; W223-V226 HydrophobicContact CZ3-CG1 4.49Å; W223-V226 PolarHBondContact O-N 3.44Å; W223-Y227 WeakPolarHBondContact O-CB 3.45Å; W223-Y227 PolarHBondContact O-N 2.97Å; W223-I260 HydrophobicContact CB-CD1 4.26Å; W223-I260 HydrophobicContact CB-CG1 4.28Å; W223-I260 HydrophobicContact CB-CG2 3.58Å; W223-I260 HydrophobicContact CG-CG2 4.41Å; W223-I295 HydrophobicContact CZ2-CG2 4.12Å; W223-I295 VanDerWaalsContact CZ2-O 3.29Å; W223-I295 WeakPolarHBondContact CZ2-O 3.42Å; W223-I299 HydrophobicContact CH2-CG2 3.97Å; W223-P300 HydrophobicContact CH2-CG 4.33Å; W223-P300 HydrophobicContact CZ2-CG 4.04Å
224	H	94.1	Very high	90.8	Very high	0 Å²	0	19.3 Å²	19.3	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-63.4	-42.7	169.8	-77.4	99.2	0	0	0	111.8	I169 S172 M173 I220 S221 E222 Y227 L228 Y261	I169-H224 HydrophobicContact CG2-CB 4.32Å; S172-H224 WeakPolarHBondContact CB-NE2 3.38Å; S172-H224 PolarHBondContact OG-CE1 3.48Å; S172-H224 PolarHBondContact OG-NE2 3.35Å; M173-H224 HydrophobicContact CB-CB 3.89Å; M173-H224 HydrophobicContact CG-CB 4.08Å; M173-H224 HydrophobicContact SD-CB 4.46Å; I220-H224 WeakPolarHBondContact CG2-CE1 3.46Å; I220-H224 VanDerWaalsContact CG2-ND1 3.26Å; I220-H224 WeakPolarHBondContact CG2-ND1 3.39Å; I220-H224 PolarHBondContact O-N 3.1Å; I220-H224 PolarHBondContact O-ND1 3.32Å; S221-H224 WeakPolarHBondContact O-CB 3.29Å; S221-H224 PolarHBondContact O-N 3.36Å; E222-H224 VanDerWaalsContact C-N 3.31Å; E222-H224 PolarHBondContact O-N 3.18Å; H224-Y227 PolarHBondContact O-N 2.95Å; H224-L228 WeakPolarHBondContact O-CB 3.47Å; H224-L228 PolarHBondContact O-N 3.3Å; H224-Y261 AromaticContact CE1-CE2 3.53Å; H224-Y261 AromaticContact NE2-CE2 3.95Å
225	F	91	Very high	90.6	Very high	13 Å²	13	21.5 Å²	21.5	6%	0.057	10%	0.098	C	C	.	.	H	α-helix	trans	-63.1	-44.7	177.7	-178.4	-113.8	0	0	0	111.5	M173 S221 E222 Y227 L228 C229 V304 A360 T411	M173-F225 HydrophobicContact CE-CB 4.02Å; M173-F225 HydrophobicContact CE-CD2 4.37Å; M173-F225 HydrophobicContact SD-CB 4.41Å; S221-F225 PolarHBondContact O-N 2.93Å; E222-F225 WeakPolarHBondContact O-CB 3.31Å; E222-F225 PolarHBondContact O-N 3.2Å; E222-F225 VanDerWaalsContact O-N 3.1Å; F225-Y227 PolarHBondContact O-N 2.73Å; F225-L228 WeakPolarHBondContact O-CB 3.4Å; F225-L228 PolarHBondContact O-N 3.45Å; F225-C229 PolarHBondContact O-N 3.29Å; F225-C229 PolarHBondContact O-SG 2.96Å; F225-V304 HydrophobicContact CD1-CG2 4.08Å; F225-V304 HydrophobicContact CE1-CG1 3.84Å; F225-V304 HydrophobicContact CE1-CG2 4.1Å; F225-A360 HydrophobicContact CE1-CB 4.29Å; F225-T411 HydrophobicContact CD2-CG2 3.95Å; F225-T411 HydrophobicContact CE2-CG2 3.49Å; F225-T411 VanDerWaalsContact CE2-CG2 3.49Å; F225-T411 HydrophobicContact CZ-CG2 4.09Å
226	V	92.7	Very high	90.4	Very high	2 Å²	2	23.1 Å²	23.1	1%	0.012	11%	0.106	C	C	.	.	H	α-helix	trans	-58.2	-48.7	174.7	176	0	0	0	0	110.7	E222 W223 L228 C229 I230 P300 I303 V304	E222-V226 HydrophobicContact CG-CG2 4.5Å; E222-V226 VanDerWaalsContact O-CG2 3.24Å; E222-V226 WeakPolarHBondContact O-CG2 3.28Å; E222-V226 PolarHBondContact O-N 2.85Å; W223-V226 HydrophobicContact CE3-CB 4.47Å; W223-V226 HydrophobicContact CE3-CG1 4.43Å; W223-V226 HydrophobicContact CZ3-CG1 4.49Å; W223-V226 PolarHBondContact O-N 3.44Å; V226-L228 VanDerWaalsContact C-N 3.33Å; V226-L228 PolarHBondContact O-N 3.37Å; V226-C229 WeakPolarHBondContact O-CB 3.26Å; V226-C229 PolarHBondContact O-N 3.02Å; V226-I230 HydrophobicContact CG1-CD1 4.09Å; V226-I230 WeakPolarHBondContact O-CG1 3.5Å; V226-I230 PolarHBondContact O-N 3.32Å; V226-P300 HydrophobicContact CG2-CB 3.61Å; V226-I303 HydrophobicContact CG1-CB 3.96Å; V226-I303 HydrophobicContact CG1-CD1 4.24Å; V226-I303 HydrophobicContact CG1-CG2 3.51Å; V226-V304 HydrophobicContact CB-CG2 4.35Å; V226-V304 HydrophobicContact CG2-CG2 3.75Å
227	Y	93.1	Very high	90.1	Very high	37 Å²	37	26 Å²	26	15%	0.145	12%	0.122	C	C	.	.	H	α-helix	trans	-63.1	-39	179.6	-178.9	-127.9	0	0	0	112.2	I169 W223 H224 F225 C229 I230 E231 T253 I256	I169-Y227 HydrophobicContact CD1-CD1 3.39Å; I169-Y227 HydrophobicContact CD1-CE1 3.18Å; I169-Y227 HydrophobicContact CD1-CG 4.45Å; I169-Y227 HydrophobicContact CG1-CD1 3.7Å; I169-Y227 HydrophobicContact CG1-CE1 3.61Å; I169-Y227 HydrophobicContact CG2-CD1 4.32Å; W223-Y227 WeakPolarHBondContact O-CB 3.45Å; W223-Y227 PolarHBondContact O-N 2.97Å; H224-Y227 PolarHBondContact O-N 2.95Å; F225-Y227 PolarHBondContact O-N 2.73Å; Y227-C229 PolarHBondContact O-N 3Å; Y227-I230 PolarHBondContact O-N 2.91Å; Y227-E231 WeakPolarHBondContact O-CB 3.21Å; Y227-E231 PolarHBondContact O-N 3.01Å; Y227-T253 HydrophobicContact CE1-CG2 4.25Å; Y227-I256 HydrophobicContact CD1-CG2 4.11Å; Y227-I256 HydrophobicContact CD2-CG2 4.07Å; Y227-I256 HydrophobicContact CE1-CB 4.37Å; Y227-I256 HydrophobicContact CE1-CG2 3.95Å; Y227-I256 HydrophobicContact CE2-CD1 3.72Å; Y227-I256 HydrophobicContact CE2-CG2 3.96Å; Y227-I256 HydrophobicContact CG-CG2 4.18Å; Y227-I256 WeakPolarHBondContact OH-CD1 3.41Å
228	L	91.1	Very high	89.6	Confident	1 Å²	1	31.3 Å²	31.3	1%	0.005	14%	0.142	C	C	.	.	H	α-helix	trans	-60.9	-43.3	173.6	-175.5	149	0	0	0	111.7	I166 I169 I170 H224 F225 V226 E231 R232 L415	I166-L228 HydrophobicContact CG2-CD1 4.46Å; I169-L228 HydrophobicContact CG2-CB 4.09Å; I169-L228 HydrophobicContact CG2-CD1 4.4Å; I170-L228 HydrophobicContact CD1-CD1 3.96Å; I170-L228 HydrophobicContact CG1-CD1 3.46Å; I170-L228 VanDerWaalsContact CG1-CD1 3.46Å; H224-L228 WeakPolarHBondContact O-CB 3.47Å; H224-L228 PolarHBondContact O-N 3.3Å; F225-L228 WeakPolarHBondContact O-CB 3.4Å; F225-L228 PolarHBondContact O-N 3.45Å; V226-L228 VanDerWaalsContact C-N 3.33Å; V226-L228 PolarHBondContact O-N 3.37Å; L228-E231 PolarHBondContact O-N 2.96Å; L228-R232 HydrophobicContact CD2-CG 4.31Å; L228-R232 WeakPolarHBondContact O-CB 3.43Å; L228-R232 VanDerWaalsContact O-CG 3.28Å; L228-R232 WeakPolarHBondContact O-CG 3.25Å; L228-R232 PolarHBondContact O-N 2.92Å; L228-L415 HydrophobicContact CD1-CD1 4.12Å; L228-L415 HydrophobicContact CD1-CD2 4.44Å; L228-L415 HydrophobicContact CD2-CD2 3.79Å
229	C	89.3	Confident	88.8	Confident	4 Å²	4	34.7 Å²	34.7	3%	0.027	17%	0.166	C	C	.	.	H	α-helix	trans	-63.4	-43.5	175.8	-72.9	0	0	0	0	112.2	F225 V226 Y227 R232 C233 S307	F225-C229 PolarHBondContact O-N 3.29Å; F225-C229 PolarHBondContact O-SG 2.96Å; V226-C229 WeakPolarHBondContact O-CB 3.26Å; V226-C229 PolarHBondContact O-N 3.02Å; Y227-C229 PolarHBondContact O-N 3Å; C229-R232 PolarHBondContact O-N 3.43Å; C229-C233 VanDerWaalsContact O-CB 3.27Å; C229-C233 WeakPolarHBondContact O-CB 3.21Å; C229-C233 PolarHBondContact O-N 3.45Å; C229-S307 WeakPolarHBondContact CB-OG 3.36Å
230	I	90.7	Very high	87.4	Confident	74 Å²	74	45.1 Å²	45.1	38%	0.379	20%	0.204	S	C	.	.	H	α-helix	trans	-60.9	-49.2	174.9	-65	168.5	0	0	0	110.3	V226 Y227 R232 C233 Y234 I303	V226-I230 HydrophobicContact CG1-CD1 4.09Å; V226-I230 WeakPolarHBondContact O-CG1 3.5Å; V226-I230 PolarHBondContact O-N 3.32Å; Y227-I230 PolarHBondContact O-N 2.91Å; I230-R232 VanDerWaalsContact C-N 3.34Å; I230-R232 PolarHBondContact O-N 2.89Å; I230-C233 PolarHBondContact O-N 3.42Å; I230-Y234 WeakPolarHBondContact O-CB 3.37Å; I230-Y234 PolarHBondContact O-N 3.36Å; I230-I303 HydrophobicContact CD1-CG2 3.77Å; I230-I303 HydrophobicContact CG1-CG2 3.73Å
231	E	87.9	Confident	85.7	Confident	9 Å²	9	52.2 Å²	52.2	4%	0.042	24%	0.235	C	C	.	.	H	α-helix	trans	-61.6	-44.6	-177.8	-166.6	-172.4	174	0	0	111	R163 S165 I166 I169 Y227 L228 C233 Y234 I235	R163-E231 IonicContact NH1-OE1 2.72Å; R163-E231 PolarHBondContact NH1-OE1 2.93Å; S165-E231 WeakPolarHBondContact CB-OE1 3.25Å; S165-E231 PolarHBondContact OG-OE1 3.43Å; I166-E231 WeakPolarHBondContact CG1-OE2 3.4Å; I169-E231 WeakPolarHBondContact CD1-OE2 3.48Å; Y227-E231 WeakPolarHBondContact O-CB 3.21Å; Y227-E231 PolarHBondContact O-N 3.01Å; L228-E231 PolarHBondContact O-N 2.96Å; E231-C233 PolarHBondContact O-N 3.42Å; E231-Y234 PolarHBondContact O-N 3.2Å; E231-I235 HydrophobicContact CG-CD1 3.96Å; E231-I235 VanDerWaalsContact O-CG1 3.26Å; E231-I235 WeakPolarHBondContact O-CG1 3.26Å; E231-I235 PolarHBondContact O-N 2.97Å
232	R	85.7	Confident	84	Confident	47 Å²	47	54.7 Å²	54.7	18%	0.177	25%	0.245	C	C	.	.	H	α-helix	trans	-63.4	-41.8	177	-72.1	-177.8	71.1	153.9	3.5	112.2	L228 C229 I230 I235 I236 M311 M356	L228-R232 HydrophobicContact CD2-CG 4.31Å; L228-R232 WeakPolarHBondContact O-CB 3.43Å; L228-R232 VanDerWaalsContact O-CG 3.28Å; L228-R232 WeakPolarHBondContact O-CG 3.25Å; L228-R232 PolarHBondContact O-N 2.92Å; C229-R232 PolarHBondContact O-N 3.43Å; I230-R232 VanDerWaalsContact C-N 3.34Å; I230-R232 PolarHBondContact O-N 2.89Å; R232-I235 PolarHBondContact O-N 3.31Å; R232-I236 WeakPolarHBondContact O-CG1 3.48Å; R232-I236 PolarHBondContact O-N 3.47Å; R232-I236 VanDerWaalsContact O-N 3.11Å; R232-M311 HydrophobicContact CB-SD 3.75Å; R232-M356 PolarHBondContact NH1-SD 2.89Å
233	C	88.9	Confident	82.2	Confident	9 Å²	9	58.9 Å²	58.9	6%	0.061	28%	0.275	C	S	.	.	H	α-helix	trans	-61.5	-46	175.4	-174.7	0	0	0	0	111.1	C229 I230 E231 I235 I236 L237 S307 M311	C229-C233 VanDerWaalsContact O-CB 3.27Å; C229-C233 WeakPolarHBondContact O-CB 3.21Å; C229-C233 PolarHBondContact O-N 3.45Å; I230-C233 PolarHBondContact O-N 3.42Å; E231-C233 PolarHBondContact O-N 3.42Å; C233-I235 PolarHBondContact O-N 3.43Å; C233-I236 PolarHBondContact O-N 3.31Å; C233-L237 WeakPolarHBondContact O-CB 3.27Å; C233-L237 WeakPolarHBondContact O-CG 3.32Å; C233-L237 PolarHBondContact O-N 3.32Å; C233-S307 PolarHBondContact SG-O 2.95Å; C233-M311 HydrophobicContact CB-CG 3.85Å; C233-M311 HydrophobicContact CB-SD 4.28Å
234	Y	87.7	Confident	80.1	Confident	88 Å²	88	64.7 Å²	64.7	35%	0.345	30%	0.304	S	S	.	.	H	α-helix	trans	-59	-47.8	177.8	-170.4	-72.9	0	0	0	111.9	I230 E231 I236 L237 Y238 Y242	I230-Y234 WeakPolarHBondContact O-CB 3.37Å; I230-Y234 PolarHBondContact O-N 3.36Å; E231-Y234 PolarHBondContact O-N 3.2Å; Y234-I236 VanDerWaalsContact C-N 3.29Å; Y234-I236 PolarHBondContact O-N 2.91Å; Y234-L237 PolarHBondContact O-N 3.45Å; Y234-Y238 HydrophobicContact CD1-CD2 4.39Å; Y234-Y238 HydrophobicContact CD2-CD2 4.24Å; Y234-Y238 HydrophobicContact CE1-CD2 4.02Å; Y234-Y238 HydrophobicContact CE1-CG 4.44Å; Y234-Y238 HydrophobicContact CE2-CD2 4.03Å; Y234-Y238 HydrophobicContact CE2-CE2 4.33Å; Y234-Y238 HydrophobicContact CG-CD2 4.45Å; Y234-Y238 AromaticContact CZ-CD2 3.93Å; Y234-Y238 PolarHBondContact O-N 3.48Å; Y234-Y242 HydrophobicContact CD1-CD1 4.32Å; Y234-Y242 HydrophobicContact CD1-CD2 4.05Å; Y234-Y242 AromaticContact CD1-CE1 3.8Å; Y234-Y242 HydrophobicContact CD1-CE1 3.8Å; Y234-Y242 AromaticContact CD1-CE2 3.6Å; Y234-Y242 HydrophobicContact CD1-CE2 3.6Å; Y234-Y242 HydrophobicContact CD1-CG 4.4Å; Y234-Y242 AromaticContact CD1-CZ 3.42Å; Y234-Y242 VanDerWaalsContact CD1-CZ 3.42Å; Y234-Y242 HydrophobicContact CE1-CD1 4.38Å; Y234-Y242 AromaticContact CE1-CD2 3.32Å; Y234-Y242 HydrophobicContact CE1-CD2 3.32Å; Y234-Y242 AromaticContact CE1-CE1 3.99Å; Y234-Y242 HydrophobicContact CE1-CE1 3.99Å; Y234-Y242 AromaticContact CE1-CE2 2.9Å; Y234-Y242 HydrophobicContact CE1-CE2 2.9Å; Y234-Y242 HydrophobicContact CE1-CG 4.06Å; Y234-Y242 AromaticContact CE1-CZ 3.26Å; Y234-Y242 AromaticContact CZ-CE2 3.62Å
235	I	83.8	Confident	78.2	Confident	50 Å²	50	69.5 Å²	69.5	26%	0.256	33%	0.33	S	S	.	.	H	α-helix	trans	-60.1	-40.5	178.8	-69.7	164.8	0	0	0	111.1	I166 E231 R232 C233 S239 Y242	I166-I235 HydrophobicContact CD1-CD1 3.88Å; E231-I235 HydrophobicContact CG-CD1 3.96Å; E231-I235 VanDerWaalsContact O-CG1 3.26Å; E231-I235 WeakPolarHBondContact O-CG1 3.26Å; E231-I235 PolarHBondContact O-N 2.97Å; R232-I235 PolarHBondContact O-N 3.31Å; C233-I235 PolarHBondContact O-N 3.43Å; I235-S239 PolarHBondContact O-N 2.94Å; I235-Y242 HydrophobicContact CG1-CD1 3.99Å; I235-Y242 HydrophobicContact CG1-CE1 4.06Å
236	I	83.6	Confident	76.3	Confident	45 Å²	45	74.1 Å²	74.1	23%	0.231	36%	0.355	C	S	.	.	H	α-helix	trans	-71.1	-40.7	-179.9	-72.6	166.6	0	0	0	111.3	R232 C233 Y234 M311 V314 L315	R232-I236 WeakPolarHBondContact O-CG1 3.48Å; R232-I236 PolarHBondContact O-N 3.47Å; R232-I236 VanDerWaalsContact O-N 3.11Å; C233-I236 PolarHBondContact O-N 3.31Å; Y234-I236 VanDerWaalsContact C-N 3.29Å; Y234-I236 PolarHBondContact O-N 2.91Å; I236-M311 HydrophobicContact CD1-CB 4.4Å; I236-M311 HydrophobicContact CD1-CE 3.69Å; I236-M311 HydrophobicContact CD1-CG 3.7Å; I236-M311 HydrophobicContact CD1-SD 3.78Å; I236-V314 HydrophobicContact CG2-CB 4.01Å; I236-V314 HydrophobicContact CG2-CG1 3.59Å; I236-L315 HydrophobicContact CD1-CD1 4.36Å; I236-L315 HydrophobicContact CG2-CD2 4.45Å; I236-L315 HydrophobicContact CG2-CG 4.4Å
237	L	85.8	Confident	74.7	Confident	76 Å²	76	78.8 Å²	78.8	40%	0.398	38%	0.38	S	S	.	.	H	α-helix	trans	-68.1	-40.9	179.2	-77.4	167.9	0	0	0	112.7	C233 Y234 V314	C233-L237 WeakPolarHBondContact O-CB 3.27Å; C233-L237 WeakPolarHBondContact O-CG 3.32Å; C233-L237 PolarHBondContact O-N 3.32Å; Y234-L237 PolarHBondContact O-N 3.45Å; L237-V314 HydrophobicContact CD2-CG2 3.49Å; L237-V314 VanDerWaalsContact CD2-CG2 3.49Å; L237-V314 HydrophobicContact CG-CG2 4.39Å
238	Y	82.1	Confident	73.2	Confident	113 Å²	113	83.2 Å²	83.2	44%	0.443	41%	0.406	S	S	.	.	T	Hydrogen-bonded Turn	trans	-118.8	39.9	-170.4	-63.4	-71.5	0	0	0	114.1	Y234 R240 K241 Y242	Y234-Y238 HydrophobicContact CD1-CD2 4.39Å; Y234-Y238 HydrophobicContact CD2-CD2 4.24Å; Y234-Y238 HydrophobicContact CE1-CD2 4.02Å; Y234-Y238 HydrophobicContact CE1-CG 4.44Å; Y234-Y238 HydrophobicContact CE2-CD2 4.03Å; Y234-Y238 HydrophobicContact CE2-CE2 4.33Å; Y234-Y238 HydrophobicContact CG-CD2 4.45Å; Y234-Y238 AromaticContact CZ-CD2 3.93Å; Y234-Y238 PolarHBondContact O-N 3.48Å; Y238-R240 PolarHBondContact O-N 2.87Å; Y238-K241 PolarHBondContact O-N 3.27Å; Y238-K241 VanDerWaalsContact O-N 3.14Å; Y238-Y242 PolarHBondContact O-N 3.44Å; Y238-Y242 VanDerWaalsContact O-N 3.09Å
239	S	72.9	Confident	72	Confident	85 Å²	85	85.7 Å²	85.7	59%	0.594	42%	0.423	S	S	*	.	H	α-helix	trans	-48	-39.7	-178.2	64.3	0	0	0	0	114.1	I235 S243	I235-S239 PolarHBondContact O-N 2.94Å; S239-S243 PolarHBondContact O-N 2.97Å
240	R	62	Low	71.6	Confident	228 Å²	228	88 Å²	88	86%	0.86	43%	0.434	S	S	*	.	H	α-helix	trans	-76	-34.4	-175.7	-158.7	176.3	-172.4	176.3	2.2	114.3	Y238	Y238-R240 PolarHBondContact O-N 2.87Å
241	K	59.1	Low	71.3	Confident	149 Å²	149	92.6 Å²	92.6	65%	0.648	45%	0.452	S	S	*	.	H	α-helix	trans	-79.3	-30.1	176.9	-73.4	-172.8	177.1	-176.4	0	111.3	Y238 H244	Y238-K241 PolarHBondContact O-N 3.27Å; Y238-K241 VanDerWaalsContact O-N 3.14Å; K241-H244 PolarHBondContact O-N 3.2Å
242	Y	57.5	Low	71.1	Confident	52 Å²	52	95.5 Å²	95.5	20%	0.204	47%	0.471	C	S	.	.	H	α-helix	trans	-79	-27.1	-175.6	-114.8	-133.9	0	0	0	114.5	Y234 I235 Y238 H244 L245	Y234-Y242 HydrophobicContact CD1-CD1 4.32Å; Y234-Y242 HydrophobicContact CD1-CD2 4.05Å; Y234-Y242 AromaticContact CD1-CE1 3.8Å; Y234-Y242 HydrophobicContact CD1-CE1 3.8Å; Y234-Y242 AromaticContact CD1-CE2 3.6Å; Y234-Y242 HydrophobicContact CD1-CE2 3.6Å; Y234-Y242 HydrophobicContact CD1-CG 4.4Å; Y234-Y242 AromaticContact CD1-CZ 3.42Å; Y234-Y242 VanDerWaalsContact CD1-CZ 3.42Å; Y234-Y242 HydrophobicContact CE1-CD1 4.38Å; Y234-Y242 AromaticContact CE1-CD2 3.32Å; Y234-Y242 HydrophobicContact CE1-CD2 3.32Å; Y234-Y242 AromaticContact CE1-CE1 3.99Å; Y234-Y242 HydrophobicContact CE1-CE1 3.99Å; Y234-Y242 AromaticContact CE1-CE2 2.9Å; Y234-Y242 HydrophobicContact CE1-CE2 2.9Å; Y234-Y242 HydrophobicContact CE1-CG 4.06Å; Y234-Y242 AromaticContact CE1-CZ 3.26Å; Y234-Y242 AromaticContact CZ-CE2 3.62Å; I235-Y242 HydrophobicContact CG1-CD1 3.99Å; I235-Y242 HydrophobicContact CG1-CE1 4.06Å; Y238-Y242 PolarHBondContact O-N 3.44Å; Y238-Y242 VanDerWaalsContact O-N 3.09Å; Y242-H244 PolarHBondContact O-N 3.05Å; Y242-L245 HydrophobicContact CD2-CD1 4.07Å; Y242-L245 HydrophobicContact CE2-CD1 4.2Å; Y242-L245 PolarHBondContact O-N 3.41Å
243	S	53.4	Low	71.2	Confident	97 Å²	97	93.5 Å²	93.5	68%	0.678	46%	0.464	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.6	-15	173	-167.8	0	0	0	0	113.7	S239	S239-S243 PolarHBondContact O-N 2.97Å
244	H	49.3	Very low	71.3	Confident	179 Å²	179	96.6 Å²	96.6	83%	0.829	48%	0.479	S	S	*	.	T	Hydrogen-bonded Turn	trans	-104	-17.8	178.2	-113.1	-75	0	0	0	113.8	K241 Y242 N246	K241-H244 PolarHBondContact O-N 3.2Å; Y242-H244 PolarHBondContact O-N 3.05Å; H244-N246 PolarHBondContact O-N 3.42Å; H244-N246 VanDerWaalsContact O-N 3.12Å
245	L	54.6	Low	71.6	Confident	101 Å²	101	98.9 Å²	98.9	53%	0.529	49%	0.492	S	S	.	.	S	Bend	trans	-87.9	81.8	-179.1	-84.4	157.2	0	0	0	109.9	Y242 D247	Y242-L245 HydrophobicContact CD2-CD1 4.07Å; Y242-L245 HydrophobicContact CE2-CD1 4.2Å; Y242-L245 PolarHBondContact O-N 3.41Å; L245-D247 PolarHBondContact O-N 2.86Å
246	N	51.8	Low	72	Confident	111 Å²	111	99.1 Å²	99.1	59%	0.594	49%	0.493	S	S	*	.			trans	27.7	83.3	161.8	-158.3	14.2	0	0	0	114.9	H244 N248 S249	H244-N246 PolarHBondContact O-N 3.42Å; H244-N246 VanDerWaalsContact O-N 3.12Å; N246-N248 PolarHBondContact O-N 3.49Å; N246-S249 PolarHBondContact O-N 3.47Å
247	D	58.9	Low	72.5	Confident	99 Å²	99	97.7 Å²	97.7	53%	0.529	49%	0.486	S	S	.	.	T	Hydrogen-bonded Turn	trans	-53	-12.7	178.6	-86.5	-31.2	0	0	0	114.8	L245	L245-D247 PolarHBondContact O-N 2.86Å
248	N	60.5	Low	73	Confident	130 Å²	130	99.3 Å²	99.3	70%	0.695	49%	0.494	S	S	*	.	T	Hydrogen-bonded Turn	trans	-105.2	-1.9	-173.2	-69.7	-16.4	0	0	0	115.5	N246 M250	N246-N248 PolarHBondContact O-N 3.49Å; N248-M250 PolarHBondContact O-N 3.26Å
249	S	67.6	Low	73.6	Confident	53 Å²	53	97.7 Å²	97.7	37%	0.371	49%	0.493	S	S	.	.			trans	-83.4	99	-179.7	-167.9	0	0	0	0	112.1	N246 K251	N246-S249 PolarHBondContact O-N 3.47Å; S249-K251 VanDerWaalsContact C-N 3.3Å
250	M	79.3	Confident	74.7	Confident	52 Å²	52	94.5 Å²	94.5	26%	0.256	47%	0.468	S	S	.	.			trans	-73.9	-19.8	171.6	-68.4	177.2	121.5	0	0	113.7	R53 L164 N248 T253 I254	R53-M250 VanDerWaalsContact NH2-CE 3.31Å; L164-M250 HydrophobicContact CD1-CE 3.48Å; L164-M250 VanDerWaalsContact CD1-CE 3.48Å; L164-M250 HydrophobicContact CD2-CE 3.54Å; L164-M250 HydrophobicContact CD2-CG 3.35Å; L164-M250 HydrophobicContact CD2-SD 3.62Å; L164-M250 HydrophobicContact CG-CE 3.3Å; L164-M250 HydrophobicContact CG-CG 3.71Å; L164-M250 HydrophobicContact CG-SD 4.03Å; N248-M250 PolarHBondContact O-N 3.26Å; M250-T253 PolarHBondContact O-N 3Å; M250-I254 HydrophobicContact CB-CD1 3.93Å; M250-I254 HydrophobicContact CB-CG1 4.5Å; M250-I254 WeakPolarHBondContact O-CG1 3.48Å; M250-I254 PolarHBondContact O-N 2.82Å
251	K	84.2	Confident	76.3	Confident	171 Å²	171	86.7 Å²	86.7	74%	0.743	44%	0.439	S	S	*	.	H	α-helix	trans	-52.5	-50.1	-171.2	-66.3	-175	178.7	-177.4	0	114.4	S249 T253 I254 F255	S249-K251 VanDerWaalsContact C-N 3.3Å; K251-T253 VanDerWaalsContact C-N 3.34Å; K251-T253 PolarHBondContact O-N 3.35Å; K251-I254 PolarHBondContact O-N 3.09Å; K251-F255 WeakPolarHBondContact O-CB 3.39Å; K251-F255 PolarHBondContact O-N 2.58Å
252	P	85.3	Confident	78	Confident	70 Å²	70	84.4 Å²	84.4	46%	0.455	43%	0.434	S	S	.	.	H	α-helix	trans	-64.5	-38.2	-178	24.6	-34.3	0	0	0	112.4	F255 I256	P252-F255 PolarHBondContact O-N 3.27Å; P252-I256 WeakPolarHBondContact O-CG1 3.47Å; P252-I256 PolarHBondContact O-N 3.47Å
253	T	88	Confident	79.7	Confident	5 Å²	5	86.2 Å²	86.2	3%	0.031	45%	0.446	C	S	.	.	H	α-helix	trans	-66	-45.4	178.4	-61.4	0	0	0	0	111.7	S165 I169 Y227 M250 K251 F255 I256 I257	S165-T253 WeakPolarHBondContact CB-OG1 3.33Å; I169-T253 HydrophobicContact CD1-CG2 4.1Å; I169-T253 HydrophobicContact CG1-CG2 3.7Å; Y227-T253 HydrophobicContact CE1-CG2 4.25Å; M250-T253 PolarHBondContact O-N 3Å; K251-T253 VanDerWaalsContact C-N 3.34Å; K251-T253 PolarHBondContact O-N 3.35Å; T253-F255 VanDerWaalsContact C-N 3.31Å; T253-F255 PolarHBondContact O-N 2.99Å; T253-I256 PolarHBondContact O-N 3.28Å; T253-I257 HydrophobicContact CG2-CD1 3.92Å; T253-I257 WeakPolarHBondContact O-CG1 3.29Å; T253-I257 PolarHBondContact O-N 2.55Å
254	I	91.2	Very high	81.6	Confident	74 Å²	74	81.7 Å²	81.7	38%	0.379	41%	0.414	S	S	.	.	H	α-helix	trans	-61.8	-42.3	177.4	-66.1	170	0	0	0	110.6	T168 M250 K251 I256 I257 L258	T168-I254 HydrophobicContact CG2-CG1 4.48Å; M250-I254 HydrophobicContact CB-CD1 3.93Å; M250-I254 HydrophobicContact CB-CG1 4.5Å; M250-I254 WeakPolarHBondContact O-CG1 3.48Å; M250-I254 PolarHBondContact O-N 2.82Å; K251-I254 PolarHBondContact O-N 3.09Å; I254-I256 PolarHBondContact O-N 3.49Å; I254-I257 PolarHBondContact O-N 3.22Å; I254-L258 HydrophobicContact CG2-CD1 4.07Å; I254-L258 HydrophobicContact CG2-CG 4.42Å; I254-L258 WeakPolarHBondContact O-CG 3.41Å; I254-L258 PolarHBondContact O-N 2.86Å
255	F	92.5	Very high	83.6	Confident	137 Å²	137	75.1 Å²	75.1	60%	0.601	39%	0.389	S	S	*	.	H	α-helix	trans	-59.8	-45.2	176.9	178.8	-99.2	0	0	0	112.2	K251 P252 T253 L258 L259	K251-F255 WeakPolarHBondContact O-CB 3.39Å; K251-F255 PolarHBondContact O-N 2.58Å; P252-F255 PolarHBondContact O-N 3.27Å; T253-F255 VanDerWaalsContact C-N 3.31Å; T253-F255 PolarHBondContact O-N 2.99Å; F255-L258 PolarHBondContact O-N 3.14Å; F255-L259 WeakPolarHBondContact O-CB 3.41Å; F255-L259 PolarHBondContact O-N 3.48Å
256	I	93.1	Very high	85.4	Confident	54 Å²	54	75.4 Å²	75.4	28%	0.277	39%	0.39	S	S	.	.	H	α-helix	trans	-65.1	-41.8	177.5	-68.7	165.6	0	0	0	111.2	Y227 P252 T253 I254 L258 L259 I260	Y227-I256 HydrophobicContact CD1-CG2 4.11Å; Y227-I256 HydrophobicContact CD2-CG2 4.07Å; Y227-I256 HydrophobicContact CE1-CB 4.37Å; Y227-I256 HydrophobicContact CE1-CG2 3.95Å; Y227-I256 HydrophobicContact CE2-CD1 3.72Å; Y227-I256 HydrophobicContact CE2-CG2 3.96Å; Y227-I256 HydrophobicContact CG-CG2 4.18Å; Y227-I256 WeakPolarHBondContact OH-CD1 3.41Å; P252-I256 WeakPolarHBondContact O-CG1 3.47Å; P252-I256 PolarHBondContact O-N 3.47Å; T253-I256 PolarHBondContact O-N 3.28Å; I254-I256 PolarHBondContact O-N 3.49Å; I256-L258 PolarHBondContact O-N 3.2Å; I256-L259 WeakPolarHBondContact O-CB 3.38Å; I256-L259 PolarHBondContact O-N 3.12Å; I256-I260 HydrophobicContact CG2-CD1 4.04Å; I256-I260 HydrophobicContact CG2-CG1 4.5Å; I256-I260 WeakPolarHBondContact O-CG1 3.17Å; I256-I260 PolarHBondContact O-N 3Å
257	I	94.1	Very high	87	Confident	16 Å²	16	72 Å²	72	8%	0.082	38%	0.375	C	S	.	.	H	α-helix	trans	-58.7	-50	175.3	-70	169.5	0	0	0	109.9	T168 I169 T253 I254 L259 I260 Y261	T168-I257 HydrophobicContact CG2-CD1 3.79Å; I169-I257 HydrophobicContact CG1-CD1 4.29Å; T253-I257 HydrophobicContact CG2-CD1 3.92Å; T253-I257 WeakPolarHBondContact O-CG1 3.29Å; T253-I257 PolarHBondContact O-N 2.55Å; I254-I257 PolarHBondContact O-N 3.22Å; I257-L259 VanDerWaalsContact C-N 3.27Å; I257-L259 PolarHBondContact O-N 3.16Å; I257-I260 WeakPolarHBondContact O-CB 3.21Å; I257-I260 PolarHBondContact O-N 2.83Å; I257-I260 VanDerWaalsContact O-N 3.12Å; I257-Y261 HydrophobicContact CG2-CD2 3.85Å; I257-Y261 HydrophobicContact CG2-CE2 3.66Å; I257-Y261 VanDerWaalsContact O-CD2 3.25Å; I257-Y261 WeakPolarHBondContact O-CD2 3.38Å; I257-Y261 PolarHBondContact O-N 2.92Å
258	L	95.2	Very high	88.4	Confident	110 Å²	110	67.3 Å²	67.3	58%	0.576	35%	0.349	S	S	*	.	H	α-helix	trans	-58.9	-38.5	177.6	-70	172.1	0	0	0	112.5	I254 F255 I256 Y261 L262	I254-L258 HydrophobicContact CG2-CD1 4.07Å; I254-L258 HydrophobicContact CG2-CG 4.42Å; I254-L258 WeakPolarHBondContact O-CG 3.41Å; I254-L258 PolarHBondContact O-N 2.86Å; F255-L258 PolarHBondContact O-N 3.14Å; I256-L258 PolarHBondContact O-N 3.2Å; L258-Y261 PolarHBondContact O-N 3.38Å; L258-L262 WeakPolarHBondContact O-CB 3.39Å; L258-L262 PolarHBondContact O-N 2.67Å
259	L	95.1	Very high	89.7	Confident	79 Å²	79	65.5 Å²	65.5	41%	0.414	34%	0.339	S	S	.	.	H	α-helix	trans	-62.8	-44.4	175.3	-169.9	100.8	0	0	0	111.8	F255 I256 I257 L262 I263	F255-L259 WeakPolarHBondContact O-CB 3.41Å; F255-L259 PolarHBondContact O-N 3.48Å; I256-L259 WeakPolarHBondContact O-CB 3.38Å; I256-L259 PolarHBondContact O-N 3.12Å; I257-L259 VanDerWaalsContact C-N 3.27Å; I257-L259 PolarHBondContact O-N 3.16Å; L259-L262 PolarHBondContact O-N 2.9Å; L259-I263 HydrophobicContact CD2-CD1 3.72Å; L259-I263 HydrophobicContact CG-CD1 3.75Å; L259-I263 HydrophobicContact CG-CG1 4.42Å; L259-I263 WeakPolarHBondContact O-CB 3.3Å; L259-I263 VanDerWaalsContact O-CG1 3.31Å; L259-I263 WeakPolarHBondContact O-CG1 3.3Å; L259-I263 PolarHBondContact O-N 3.33Å
260	I	95.4	Very high	90.3	Very high	17 Å²	17	65.5 Å²	65.5	9%	0.087	33%	0.332	C	S	.	.	H	α-helix	trans	-58.8	-48.9	176	-69.5	166.9	0	0	0	109.9	I220 W223 I256 I257 L262 I263 S264	I220-I260 HydrophobicContact CG1-CG2 4.41Å; I220-I260 HydrophobicContact CG2-CG2 4.35Å; W223-I260 HydrophobicContact CB-CD1 4.26Å; W223-I260 HydrophobicContact CB-CG1 4.28Å; W223-I260 HydrophobicContact CB-CG2 3.58Å; W223-I260 HydrophobicContact CG-CG2 4.41Å; I256-I260 HydrophobicContact CG2-CD1 4.04Å; I256-I260 HydrophobicContact CG2-CG1 4.5Å; I256-I260 WeakPolarHBondContact O-CG1 3.17Å; I256-I260 PolarHBondContact O-N 3Å; I257-I260 WeakPolarHBondContact O-CB 3.21Å; I257-I260 PolarHBondContact O-N 2.83Å; I257-I260 VanDerWaalsContact O-N 3.12Å; I260-L262 VanDerWaalsContact C-N 3.32Å; I260-L262 PolarHBondContact O-N 3.22Å; I260-I263 PolarHBondContact O-N 3.48Å; I260-S264 WeakPolarHBondContact O-CB 3.27Å; I260-S264 PolarHBondContact O-N 3.49Å; I260-S264 PolarHBondContact O-OG 2.98Å; I260-S264 VanDerWaalsContact O-OG 3.13Å
261	Y	95.6	Very high	90.3	Very high	64 Å²	64	64 Å²	64	25%	0.251	33%	0.325	S	S	.	.	H	α-helix	trans	-58.3	-44.2	177.8	-86.2	-109.3	0	0	0	112.1	S172 I176 I220 H224 I257 L258 S265	S172-Y261 PolarHBondContact OG-OH 2.96Å; I176-Y261 HydrophobicContact CD1-CE1 4.27Å; I220-Y261 HydrophobicContact CD1-CD1 3.49Å; I220-Y261 VanDerWaalsContact CD1-CD1 3.49Å; I220-Y261 HydrophobicContact CD1-CD2 4.07Å; I220-Y261 HydrophobicContact CD1-CE1 3.77Å; I220-Y261 HydrophobicContact CD1-CE2 4.38Å; I220-Y261 HydrophobicContact CD1-CG 3.65Å; I220-Y261 HydrophobicContact CG2-CD2 4.07Å; I220-Y261 HydrophobicContact CG2-CE2 3.75Å; H224-Y261 AromaticContact CE1-CE2 3.53Å; H224-Y261 AromaticContact NE2-CE2 3.95Å; I257-Y261 HydrophobicContact CG2-CD2 3.85Å; I257-Y261 HydrophobicContact CG2-CE2 3.66Å; I257-Y261 VanDerWaalsContact O-CD2 3.25Å; I257-Y261 WeakPolarHBondContact O-CD2 3.38Å; I257-Y261 PolarHBondContact O-N 2.92Å; L258-Y261 PolarHBondContact O-N 3.38Å; Y261-S265 VanDerWaalsContact O-CB 3.31Å; Y261-S265 WeakPolarHBondContact O-CB 3.44Å; Y261-S265 PolarHBondContact O-N 3.45Å; Y261-S265 PolarHBondContact O-OG 2.86Å
262	L	95.3	Very high	90.2	Very high	101 Å²	101	57.7 Å²	57.7	53%	0.529	30%	0.3	S	S	.	.	H	α-helix	trans	-63.9	-50	179.6	-178.1	66.6	0	0	0	111.5	L258 L259 I260 S265 I266	L258-L262 WeakPolarHBondContact O-CB 3.39Å; L258-L262 PolarHBondContact O-N 2.67Å; L259-L262 PolarHBondContact O-N 2.9Å; I260-L262 VanDerWaalsContact C-N 3.32Å; I260-L262 PolarHBondContact O-N 3.22Å; L262-S265 PolarHBondContact O-N 3.27Å; L262-I266 HydrophobicContact CD1-CD1 3.98Å; L262-I266 HydrophobicContact CD1-CG1 4.46Å; L262-I266 HydrophobicContact CG-CD1 3.88Å; L262-I266 VanDerWaalsContact O-CG1 3.31Å; L262-I266 WeakPolarHBondContact O-CG1 3.15Å; L262-I266 PolarHBondContact O-N 3.44Å
263	I	93.8	Very high	89.8	Confident	90 Å²	90	59.1 Å²	59.1	46%	0.462	30%	0.302	S	S	.	.	H	α-helix	trans	-62.6	-46.3	-178.9	-67.6	169.2	0	0	0	110.5	L259 I260 S265 I266 S267	L259-I263 HydrophobicContact CD2-CD1 3.72Å; L259-I263 HydrophobicContact CG-CD1 3.75Å; L259-I263 HydrophobicContact CG-CG1 4.42Å; L259-I263 WeakPolarHBondContact O-CB 3.3Å; L259-I263 VanDerWaalsContact O-CG1 3.31Å; L259-I263 WeakPolarHBondContact O-CG1 3.3Å; L259-I263 PolarHBondContact O-N 3.33Å; I260-I263 PolarHBondContact O-N 3.48Å; I263-S265 VanDerWaalsContact C-N 3.28Å; I263-S265 PolarHBondContact O-N 3.48Å; I263-I266 PolarHBondContact O-N 3.28Å; I263-S267 WeakPolarHBondContact O-CB 3.37Å; I263-S267 PolarHBondContact O-N 3.47Å; I263-S267 PolarHBondContact O-OG 3.46Å
264	S	92.8	Very high	88.5	Confident	2 Å²	2	63.3 Å²	63.3	1%	0.014	33%	0.329	C	S	.	.	H	α-helix	trans	-63.9	-33	177.4	-64.9	0	0	0	0	112.7	I220 I260 S267 N268	I220-S264 VanDerWaalsContact CG1-CB 3.47Å; I260-S264 WeakPolarHBondContact O-CB 3.27Å; I260-S264 PolarHBondContact O-N 3.49Å; I260-S264 PolarHBondContact O-OG 2.98Å; I260-S264 VanDerWaalsContact O-OG 3.13Å; S264-S267 WeakPolarHBondContact CA-OG 3.49Å; S264-S267 PolarHBondContact O-OG 3.35Å; S264-N268 PolarHBondContact O-N 2.99Å; S264-N268 PolarHBondContact O-ND2 3.3Å
265	S	92.3	Very high	86.9	Confident	42 Å²	42	68.2 Å²	68.2	29%	0.294	35%	0.345	S	S	.	.	H	α-helix	trans	-69.6	-44.9	175.3	-59.8	0	0	0	0	111.6	Y261 L262 I263 N268 I269	Y261-S265 VanDerWaalsContact O-CB 3.31Å; Y261-S265 WeakPolarHBondContact O-CB 3.44Å; Y261-S265 PolarHBondContact O-N 3.45Å; Y261-S265 PolarHBondContact O-OG 2.86Å; L262-S265 PolarHBondContact O-N 3.27Å; I263-S265 VanDerWaalsContact C-N 3.28Å; I263-S265 PolarHBondContact O-N 3.48Å; S265-N268 PolarHBondContact O-N 3.09Å; S265-I269 PolarHBondContact O-N 3.3Å; S265-I269 VanDerWaalsContact O-N 3.08Å
266	I	90.8	Very high	85.2	Confident	106 Å²	106	68.6 Å²	68.6	54%	0.544	34%	0.343	S	S	.	.	H	α-helix	trans	-65.3	-42.7	178	-66.8	167.9	0	0	0	110.6	L262 I263 N268 I269	L262-I266 HydrophobicContact CD1-CD1 3.98Å; L262-I266 HydrophobicContact CD1-CG1 4.46Å; L262-I266 HydrophobicContact CG-CD1 3.88Å; L262-I266 VanDerWaalsContact O-CG1 3.31Å; L262-I266 WeakPolarHBondContact O-CG1 3.15Å; L262-I266 PolarHBondContact O-N 3.44Å; I263-I266 PolarHBondContact O-N 3.28Å; I266-N268 PolarHBondContact O-N 3Å; I266-I269 VanDerWaalsContact O-CG2 3.28Å; I266-I269 WeakPolarHBondContact O-CG2 3.21Å; I266-I269 PolarHBondContact O-N 2.91Å
267	S	87	Confident	83.3	Confident	40 Å²	40	68.6 Å²	68.6	28%	0.28	35%	0.348	S	S	.	.	H	α-helix	trans	-63	-25.2	-179.3	66.7	0	0	0	0	113	I263 S264 F270	I263-S267 WeakPolarHBondContact O-CB 3.37Å; I263-S267 PolarHBondContact O-N 3.47Å; I263-S267 PolarHBondContact O-OG 3.46Å; S264-S267 WeakPolarHBondContact CA-OG 3.49Å; S264-S267 PolarHBondContact O-OG 3.35Å; S267-F270 VanDerWaalsContact O-CD1 3.24Å; S267-F270 WeakPolarHBondContact O-CD1 3.37Å; S267-F270 WeakPolarHBondContact O-CE1 3.5Å
268	N	87.1	Confident	81.4	Confident	0 Å²	0	70.8 Å²	70.8	0%	0	36%	0.359	C	S	.	.	H	α-helix	trans	-108.1	-0.1	-177.3	-71.5	-68.4	0	0	0	114.4	F212 I216 D219 S264 S265 I266 F270 L271 K292	F212-N268 HydrophobicContact CD2-CB 4.24Å; F212-N268 WeakPolarHBondContact CD2-O 3.38Å; F212-N268 HydrophobicContact CE2-CB 4.19Å; I216-N268 HydrophobicContact CD1-CB 4.45Å; I216-N268 HydrophobicContact CG1-CB 3.91Å; D219-N268 PolarHBondContact OD2-ND2 3.32Å; S264-N268 PolarHBondContact O-N 2.99Å; S264-N268 PolarHBondContact O-ND2 3.3Å; S265-N268 PolarHBondContact O-N 3.09Å; I266-N268 PolarHBondContact O-N 3Å; N268-F270 PolarHBondContact O-N 3.3Å; N268-F270 VanDerWaalsContact O-N 3.1Å; N268-L271 HydrophobicContact CB-CD1 4.17Å; N268-L271 WeakPolarHBondContact O-CB 3.46Å; N268-L271 WeakPolarHBondContact O-CG 3.44Å; N268-L271 PolarHBondContact O-N 3.4Å; N268-K292 VanDerWaalsContact OD1-CE 3.31Å; N268-K292 WeakPolarHBondContact OD1-CE 3.48Å; N268-K292 PolarHBondContact OD1-NZ 2.89Å
269	I	88	Confident	79.1	Confident	93 Å²	93	70 Å²	70	48%	0.477	35%	0.349	S	S	.	.	G	3₁₀ helix	trans	-58.7	-29	-176.1	-158.7	167.5	0	0	0	113	S265 I266 L271 L272	S265-I269 PolarHBondContact O-N 3.3Å; S265-I269 VanDerWaalsContact O-N 3.08Å; I266-I269 VanDerWaalsContact O-CG2 3.28Å; I266-I269 WeakPolarHBondContact O-CG2 3.21Å; I266-I269 PolarHBondContact O-N 2.91Å; I269-L271 PolarHBondContact O-N 3.33Å; I269-L271 VanDerWaalsContact O-N 3.11Å; I269-L272 PolarHBondContact O-N 3.05Å
270	F	81.2	Confident	76.8	Confident	52 Å²	52	72 Å²	72	23%	0.228	36%	0.36	C	S	.	.	G	3₁₀ helix	trans	-58.9	-23.5	177.6	73.9	-92.4	0	0	0	113.1	S267 N268 L272 I273 V288	S267-F270 VanDerWaalsContact O-CD1 3.24Å; S267-F270 WeakPolarHBondContact O-CD1 3.37Å; S267-F270 WeakPolarHBondContact O-CE1 3.5Å; N268-F270 PolarHBondContact O-N 3.3Å; N268-F270 VanDerWaalsContact O-N 3.1Å; F270-L272 PolarHBondContact O-N 3Å; F270-I273 PolarHBondContact O-N 3.01Å; F270-V288 HydrophobicContact CE1-CG1 4.06Å; F270-V288 HydrophobicContact CE2-CG1 3.83Å; F270-V288 HydrophobicContact CZ-CG1 3.49Å; F270-V288 VanDerWaalsContact CZ-CG1 3.49Å
271	L	78.3	Confident	74.7	Confident	21 Å²	21	77.9 Å²	77.9	11%	0.11	39%	0.387	C	S	.	.	G	3₁₀ helix	trans	-69.2	-21.6	176.9	-64.5	172.6	0	0	0	112.9	I211 F212 F215 N268 I269 C382	I211-L271 HydrophobicContact CG2-CD1 4.44Å; F212-L271 HydrophobicContact CD2-CB 4.47Å; F215-L271 HydrophobicContact CB-CD1 3.81Å; F215-L271 HydrophobicContact CD1-CD1 4.5Å; F215-L271 HydrophobicContact CD2-CD1 3.63Å; F215-L271 HydrophobicContact CE2-CD1 4.4Å; F215-L271 HydrophobicContact CG-CD1 3.68Å; N268-L271 HydrophobicContact CB-CD1 4.17Å; N268-L271 WeakPolarHBondContact O-CB 3.46Å; N268-L271 WeakPolarHBondContact O-CG 3.44Å; N268-L271 PolarHBondContact O-N 3.4Å; I269-L271 PolarHBondContact O-N 3.33Å; I269-L271 VanDerWaalsContact O-N 3.11Å; L271-C382 HydrophobicContact CD2-CB 4.48Å
272	L	82.5	Confident	72.8	Confident	39 Å²	39	77.4 Å²	77.4	20%	0.204	39%	0.392	C	S	.	.	T	Hydrogen-bonded Turn	trans	-86.9	-25.8	177.1	-64.2	176	0	0	0	112.1	R208 F212 I269 F270 P274	R208-L272 HydrophobicContact CB-CD2 4.4Å; R208-L272 PolarHBondContact NH1-O 3.11Å; F212-L272 HydrophobicContact CB-CD2 3.72Å; F212-L272 HydrophobicContact CB-CG 4.17Å; F212-L272 HydrophobicContact CD1-CD1 4.03Å; F212-L272 HydrophobicContact CD1-CD2 4.22Å; F212-L272 HydrophobicContact CD1-CG 4.32Å; F212-L272 HydrophobicContact CD2-CD1 3.91Å; F212-L272 HydrophobicContact CD2-CD2 4.24Å; F212-L272 HydrophobicContact CD2-CG 3.73Å; F212-L272 HydrophobicContact CE1-CD1 3.91Å; F212-L272 HydrophobicContact CE2-CD1 3.79Å; F212-L272 HydrophobicContact CE2-CG 4.08Å; F212-L272 HydrophobicContact CG-CD1 4Å; F212-L272 HydrophobicContact CG-CD2 3.83Å; F212-L272 HydrophobicContact CG-CG 3.83Å; F212-L272 HydrophobicContact CZ-CD1 3.76Å; F212-L272 HydrophobicContact CZ-CG 4.5Å; I269-L272 PolarHBondContact O-N 3.05Å; F270-L272 PolarHBondContact O-N 3Å; L272-P274 WeakPolarHBondContact O-CD 3.34Å
273	I	75.8	Confident	70.7	Confident	99 Å²	99	77.1 Å²	77.1	51%	0.508	39%	0.386	S	S	.	.	S	Bend	trans	-75.8	123.7	-173.9	-56.8	176.1	0	0	0	109.8	R208 F270 Y275	R208-I273 PolarHBondContact NH1-O 3.21Å; F270-I273 PolarHBondContact O-N 3.01Å; I273-Y275 PolarHBondContact O-N 3.1Å; I273-Y275 VanDerWaalsContact O-N 3.14Å
274	P	61.1	Low	69.1	Low	93 Å²	93	78.7 Å²	78.7	60%	0.604	39%	0.39	S	S	*	.			trans	-77.2	99.2	176.5	30.9	-32.2	0	0	0	110.4	L272	L272-P274 WeakPolarHBondContact O-CD 3.34Å
275	Y	57.1	Low	67.9	Low	178 Å²	178	80.4 Å²	80.4	70%	0.698	40%	0.402	S	S	*	.	S	Bend	trans	-95.1	-27.8	160.6	-124.8	-87	0	0	0	112	I273	I273-Y275 PolarHBondContact O-N 3.1Å; I273-Y275 VanDerWaalsContact O-N 3.14Å
276	Y	57	Low	67	Low	145 Å²	145	85.7 Å²	85.7	57%	0.569	42%	0.42	S	S	*	.	S	Bend	trans	-147.9	155.5	178.1	-63	-79.5	0	0	0	110.7	R208 I278	R208-Y276 PolarHBondContact NH2-O 2.88Å; Y276-I278 PolarHBondContact O-N 2.71Å
277	S	53.8	Low	66.4	Low	53 Å²	53	86.5 Å²	86.5	37%	0.371	43%	0.425	S	S	.	.			trans	-65.4	126.5	169.7	73.6	0	0	0	0	108.6	Y279 N280	S277-Y279 PolarHBondContact O-N 2.96Å; S277-N280 PolarHBondContact O-N 3.39Å
278	I	53.7	Low	65.9	Low	63 Å²	63	86.2 Å²	86.2	32%	0.323	42%	0.421	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62.9	-12.4	-176.8	-70.9	163.6	0	0	0	112.7	R208 Y276	R208-I278 HydrophobicContact CB-CD1 4.4Å; R208-I278 HydrophobicContact CG-CD1 3.13Å; Y276-I278 PolarHBondContact O-N 2.71Å
279	Y	47.7	Very low	65.5	Low	94 Å²	94	88.5 Å²	88.5	37%	0.369	43%	0.43	S	S	.	.	T	Hydrogen-bonded Turn	trans	-76.3	-28.2	-176.3	-76.8	-87	0	0	0	114.8	L200 E204 S277	L200-Y279 HydrophobicContact CD2-CD1 4.28Å; L200-Y279 HydrophobicContact CD2-CE1 3.65Å; E204-Y279 HydrophobicContact CB-CE2 4.28Å; E204-Y279 HydrophobicContact CG-CE2 4.35Å; S277-Y279 PolarHBondContact O-N 2.96Å
280	N	47.2	Very low	65.2	Low	120 Å²	120	88.8 Å²	88.8	64%	0.642	43%	0.431	S	S	*	.	T	Hydrogen-bonded Turn	trans	-112	-33.8	-161.9	-75	-11	0	0	0	115.9	S277	S277-N280 PolarHBondContact O-N 3.39Å
281	E	51.2	Low	65.3	Low	141 Å²	141	89.5 Å²	89.5	66%	0.659	44%	0.44	S	S	*	.			trans	-141.4	138.2	-175.6	-67.8	-176.6	171.8	0	0	112.8	F283	E281-F283 PolarHBondContact O-N 3.44Å
282	P	54.2	Low	65.5	Low	54 Å²	54	89.2 Å²	89.2	35%	0.351	44%	0.438	S	S	.	.			trans	-66.6	126.7	175.4	27.4	-32.1	0	0	0	110.1	K284 D378 C381	P282-K284 PolarHBondContact O-N 3.03Å; P282-D378 WeakPolarHBondContact CB-O 3.42Å; P282-D378 VanDerWaalsContact CG-O 3.24Å; P282-D378 WeakPolarHBondContact CG-O 3.24Å; P282-C381 HydrophobicContact CB-CB 4.09Å
283	F	52.9	Low	65.7	Low	94 Å²	94	89.1 Å²	89.1	41%	0.412	44%	0.437	S	S	.	.			trans	-69.4	97.2	173.2	179.4	-96.5	0	0	0	109.6	E281 S285 V288 C381	E281-F283 PolarHBondContact O-N 3.44Å; F283-S285 PolarHBondContact O-N 3Å; F283-V288 HydrophobicContact CE1-CG2 4.24Å; F283-C381 PolarHBondContact N-SG 2.94Å; F283-C381 VanDerWaalsContact N-SG 3.42Å
284	K	60.2	Low	66.3	Low	123 Å²	123	86.3 Å²	86.3	54%	0.535	43%	0.426	S	S	.	.			trans	-98	85	179.3	-170.2	174.6	179.8	172.7	0	111	P282 D378	P282-K284 PolarHBondContact O-N 3.03Å; K284-D378 WeakPolarHBondContact CE-OD1 3.41Å; K284-D378 IonicContact NZ-OD1 2.68Å; K284-D378 PolarHBondContact NZ-OD1 3.31Å; K284-D378 IonicContact NZ-OD2 2.76Å; K284-D378 PolarHBondContact NZ-OD2 3.49Å
285	S	66.8	Low	67.5	Low	38 Å²	38	84.6 Å²	84.6	27%	0.266	41%	0.412	S	S	.	.			trans	-102.5	104.1	161.7	179	0	0	0	0	109.6	F283 L287 V288 Y289	F283-S285 PolarHBondContact O-N 3Å; S285-L287 PolarHBondContact O-N 3.34Å; S285-V288 PolarHBondContact O-N 3.03Å; S285-V288 VanDerWaalsContact O-N 3.09Å; S285-V288 PolarHBondContact OG-N 2.98Å; S285-Y289 PolarHBondContact O-N 2.98Å
286	K	73.9	Confident	68.9	Low	154 Å²	154	76.6 Å²	76.6	67%	0.67	38%	0.381	S	S	*	.	H	α-helix	trans	-52.8	-36	173.5	-72.8	-174.4	179.1	-179.7	0	111.3	Y289 I290	K286-Y289 PolarHBondContact O-N 3.47Å; K286-I290 VanDerWaalsContact O-CG1 3.25Å; K286-I290 WeakPolarHBondContact O-CG1 3.24Å; K286-I290 PolarHBondContact O-N 3.35Å
287	L	77.6	Confident	70.3	Confident	123 Å²	123	71.4 Å²	71.4	64%	0.644	36%	0.362	S	S	*	.	H	α-helix	trans	-64.4	-47.8	177.9	-175.2	146.2	0	0	0	111.4	S285 Y289 I290 V291	S285-L287 PolarHBondContact O-N 3.34Å; L287-Y289 VanDerWaalsContact C-N 3.28Å; L287-Y289 PolarHBondContact O-N 2.95Å; L287-I290 PolarHBondContact O-N 3.41Å; L287-V291 HydrophobicContact CD2-CG2 4.11Å; L287-V291 HydrophobicContact CG-CG2 4.46Å; L287-V291 WeakPolarHBondContact O-CB 3.12Å; L287-V291 VanDerWaalsContact O-CG2 3.23Å; L287-V291 WeakPolarHBondContact O-CG2 3.06Å; L287-V291 PolarHBondContact O-N 3.25Å
288	V	76.8	Confident	72	Confident	33 Å²	33	72.5 Å²	72.5	20%	0.2	36%	0.363	C	S	.	.	H	α-helix	trans	-61	-41.2	177.1	173.4	0	0	0	0	110.7	F270 F283 S285 K292	F270-V288 HydrophobicContact CE1-CG1 4.06Å; F270-V288 HydrophobicContact CE2-CG1 3.83Å; F270-V288 HydrophobicContact CZ-CG1 3.49Å; F270-V288 VanDerWaalsContact CZ-CG1 3.49Å; F283-V288 HydrophobicContact CE1-CG2 4.24Å; S285-V288 PolarHBondContact O-N 3.03Å; S285-V288 VanDerWaalsContact O-N 3.09Å; S285-V288 PolarHBondContact OG-N 2.98Å; V288-K292 WeakPolarHBondContact O-CB 3.26Å; V288-K292 WeakPolarHBondContact O-CG 3.34Å; V288-K292 PolarHBondContact O-N 2.94Å
289	Y	78.1	Confident	73.8	Confident	48 Å²	48	73.2 Å²	73.2	19%	0.188	37%	0.366	C	S	.	.	H	α-helix	trans	-62	-49.3	176.8	177.6	-89.5	0	0	0	112.4	S285 K286 L287 V291 K292 L293 F371 S375 F383	S285-Y289 PolarHBondContact O-N 2.98Å; K286-Y289 PolarHBondContact O-N 3.47Å; L287-Y289 VanDerWaalsContact C-N 3.28Å; L287-Y289 PolarHBondContact O-N 2.95Å; Y289-V291 PolarHBondContact O-N 3.48Å; Y289-K292 PolarHBondContact O-N 3.41Å; Y289-L293 HydrophobicContact CE1-CD2 4.41Å; Y289-L293 WeakPolarHBondContact O-CB 3.37Å; Y289-L293 PolarHBondContact O-N 2.7Å; Y289-F371 AromaticContact CE2-CD1 3.88Å; Y289-F371 HydrophobicContact CE2-CD1 3.88Å; Y289-F371 AromaticContact CZ-CD1 3.84Å; Y289-F371 WeakPolarHBondContact OH-CB 3.32Å; Y289-F371 PolarHBondContact OH-O 2.89Å; Y289-S375 WeakPolarHBondContact OH-CB 3.16Å; Y289-F383 HydrophobicContact CD2-CE1 4.03Å; Y289-F383 AromaticContact CD2-CZ 3.56Å; Y289-F383 HydrophobicContact CD2-CZ 3.56Å; Y289-F383 AromaticContact CE2-CE1 3.58Å; Y289-F383 HydrophobicContact CE2-CE1 3.58Å; Y289-F383 AromaticContact CE2-CZ 3.58Å; Y289-F383 HydrophobicContact CE2-CZ 3.58Å
290	I	82.4	Confident	75.9	Confident	99 Å²	99	68.8 Å²	68.8	51%	0.508	35%	0.349	S	S	.	.	H	α-helix	trans	-63.3	-42.4	179.3	-68.8	165.1	0	0	0	111.2	K286 L287 L293 S294	K286-I290 VanDerWaalsContact O-CG1 3.25Å; K286-I290 WeakPolarHBondContact O-CG1 3.24Å; K286-I290 PolarHBondContact O-N 3.35Å; L287-I290 PolarHBondContact O-N 3.41Å; I290-L293 PolarHBondContact O-N 2.95Å; I290-S294 WeakPolarHBondContact O-CB 3.13Å; I290-S294 PolarHBondContact O-N 3.48Å; I290-S294 PolarHBondContact O-OG 2.93Å
291	V	83.7	Confident	77.9	Confident	67 Å²	67	63.3 Å²	63.3	41%	0.406	32%	0.32	S	S	.	.	H	α-helix	trans	-63.7	-45.1	177.5	170.4	0	0	0	0	110.4	L287 Y289 S294 I295	L287-V291 HydrophobicContact CD2-CG2 4.11Å; L287-V291 HydrophobicContact CG-CG2 4.46Å; L287-V291 WeakPolarHBondContact O-CB 3.12Å; L287-V291 VanDerWaalsContact O-CG2 3.23Å; L287-V291 WeakPolarHBondContact O-CG2 3.06Å; L287-V291 PolarHBondContact O-N 3.25Å; Y289-V291 PolarHBondContact O-N 3.48Å; V291-S294 PolarHBondContact O-N 2.92Å; V291-I295 HydrophobicContact CG1-CD1 3.6Å; V291-I295 HydrophobicContact CG1-CG1 4.4Å; V291-I295 WeakPolarHBondContact O-CG1 3.28Å; V291-I295 PolarHBondContact O-N 3.41Å
292	K	82.8	Confident	79.8	Confident	15 Å²	15	61.2 Å²	61.2	7%	0.065	31%	0.313	C	S	.	.	H	α-helix	trans	-61.7	-49.8	175.6	-81.4	-162	163.5	-167.7	0	111.8	N268 V288 Y289 S294 I295 T296 F383	N268-K292 VanDerWaalsContact OD1-CE 3.31Å; N268-K292 WeakPolarHBondContact OD1-CE 3.48Å; N268-K292 PolarHBondContact OD1-NZ 2.89Å; V288-K292 WeakPolarHBondContact O-CB 3.26Å; V288-K292 WeakPolarHBondContact O-CG 3.34Å; V288-K292 PolarHBondContact O-N 2.94Å; Y289-K292 PolarHBondContact O-N 3.41Å; K292-S294 PolarHBondContact O-N 3.02Å; K292-S294 VanDerWaalsContact O-N 3.15Å; K292-I295 PolarHBondContact O-N 3.48Å; K292-I295 VanDerWaalsContact O-N 3.12Å; K292-T296 PolarHBondContact O-N 3.12Å; K292-T296 PolarHBondContact O-OG1 2.95Å; K292-F383 HydrophobicContact CB-CE2 4.12Å; K292-F383 HydrophobicContact CD-CD2 4.43Å; K292-F383 HydrophobicContact CD-CE2 3.85Å
293	L	85.5	Confident	81.7	Confident	38 Å²	38	61.2 Å²	61.2	20%	0.199	31%	0.31	C	S	.	.	H	α-helix	trans	-52.5	-39.5	175	178.4	69.9	0	0	0	112.1	Y289 I290 F297 I298 F371	Y289-L293 HydrophobicContact CE1-CD2 4.41Å; Y289-L293 WeakPolarHBondContact O-CB 3.37Å; Y289-L293 PolarHBondContact O-N 2.7Å; I290-L293 PolarHBondContact O-N 2.95Å; L293-F297 HydrophobicContact CD1-CB 4.16Å; L293-F297 HydrophobicContact CD1-CD1 3.78Å; L293-F297 HydrophobicContact CD1-CG 4.26Å; L293-F297 VanDerWaalsContact O-CB 3.31Å; L293-F297 WeakPolarHBondContact O-CB 3.34Å; L293-F297 PolarHBondContact O-N 2.97Å; L293-I298 HydrophobicContact CG-CD1 4.32Å; L293-I298 HydrophobicContact CG-CG1 4.49Å; L293-I298 PolarHBondContact O-N 3.16Å; L293-F371 HydrophobicContact CB-CD1 3.85Å; L293-F371 HydrophobicContact CB-CE1 3.68Å; L293-F371 HydrophobicContact CB-CZ 4.4Å; L293-F371 HydrophobicContact CD1-CB 3.81Å; L293-F371 HydrophobicContact CD1-CD1 3.37Å; L293-F371 HydrophobicContact CD1-CD2 3.7Å; L293-F371 HydrophobicContact CD1-CE1 3.85Å; L293-F371 HydrophobicContact CD1-CE2 4.19Å; L293-F371 HydrophobicContact CD1-CG 3.34Å; L293-F371 HydrophobicContact CD1-CZ 4.28Å; L293-F371 HydrophobicContact CG-CD1 4.18Å; L293-F371 HydrophobicContact CG-CE1 4.39Å
294	S	88.7	Confident	83.5	Confident	39 Å²	39	57 Å²	57	27%	0.273	29%	0.292	S	S	.	.	I	π-helix	trans	-69.8	-48.3	178.5	-56.1	0	0	0	0	112.2	I290 V291 K292 I299	I290-S294 WeakPolarHBondContact O-CB 3.13Å; I290-S294 PolarHBondContact O-N 3.48Å; I290-S294 PolarHBondContact O-OG 2.93Å; V291-S294 PolarHBondContact O-N 2.92Å; K292-S294 PolarHBondContact O-N 3.02Å; K292-S294 VanDerWaalsContact O-N 3.15Å; S294-I299 WeakPolarHBondContact O-CB 3.3Å; S294-I299 WeakPolarHBondContact O-CG1 3.32Å; S294-I299 PolarHBondContact O-N 3.48Å
295	I	86.9	Confident	84.9	Confident	58 Å²	58	54.2 Å²	54.2	30%	0.297	28%	0.282	S	S	.	.	I	π-helix	trans	-76.8	-32.8	-173.2	-66.9	174.8	0	0	0	112.7	W223 V291 K292 P300	W223-I295 HydrophobicContact CZ2-CG2 4.12Å; W223-I295 VanDerWaalsContact CZ2-O 3.29Å; W223-I295 WeakPolarHBondContact CZ2-O 3.42Å; V291-I295 HydrophobicContact CG1-CD1 3.6Å; V291-I295 HydrophobicContact CG1-CG1 4.4Å; V291-I295 WeakPolarHBondContact O-CG1 3.28Å; V291-I295 PolarHBondContact O-N 3.41Å; K292-I295 PolarHBondContact O-N 3.48Å; K292-I295 VanDerWaalsContact O-N 3.12Å; I295-P300 WeakPolarHBondContact O-CD 3.45Å; I295-P300 WeakPolarHBondContact O-CG 3.34Å
296	T	85.6	Confident	86.1	Confident	10 Å²	10	57.3 Å²	57.3	6%	0.061	29%	0.294	C	S	.	.	I	π-helix	trans	-111.8	4.5	-173.4	73.7	0	0	0	0	112.8	D219 E222 K292 L367 F371	D219-T296 WeakPolarHBondContact OD1-CG2 3.47Å; E222-T296 VanDerWaalsContact CD-O 3.23Å; E222-T296 WeakPolarHBondContact OE2-CA 3.24Å; K292-T296 PolarHBondContact O-N 3.12Å; K292-T296 PolarHBondContact O-OG1 2.95Å; T296-L367 WeakPolarHBondContact O-CD2 3.4Å; T296-F371 WeakPolarHBondContact OG1-CZ 3.34Å
297	F	86.6	Confident	87	Confident	36 Å²	36	50.3 Å²	50.3	16%	0.158	27%	0.265	C	S	.	.	I	π-helix	trans	-139.2	-59	175.7	172.6	-104.2	0	0	0	111.9	L293 G301 L364 L367 L368 F371	L293-F297 HydrophobicContact CD1-CB 4.16Å; L293-F297 HydrophobicContact CD1-CD1 3.78Å; L293-F297 HydrophobicContact CD1-CG 4.26Å; L293-F297 VanDerWaalsContact O-CB 3.31Å; L293-F297 WeakPolarHBondContact O-CB 3.34Å; L293-F297 PolarHBondContact O-N 2.97Å; F297-G301 WeakPolarHBondContact O-CA 3.38Å; F297-G301 PolarHBondContact O-N 3.21Å; F297-L364 HydrophobicContact CD2-CD2 3.75Å; F297-L364 HydrophobicContact CE2-CB 3.94Å; F297-L364 HydrophobicContact CE2-CD2 3.66Å; F297-L364 HydrophobicContact CE2-CG 4.4Å; F297-L364 WeakPolarHBondContact CE2-O 3.49Å; F297-L367 HydrophobicContact CB-CD2 4.27Å; F297-L367 HydrophobicContact CB-CG 4.46Å; F297-L367 HydrophobicContact CD2-CB 4.13Å; F297-L367 HydrophobicContact CD2-CD2 4.04Å; F297-L367 HydrophobicContact CD2-CG 4Å; F297-L368 HydrophobicContact CE1-CD1 3.89Å; F297-L368 HydrophobicContact CE2-CB 3.9Å; F297-L368 HydrophobicContact CZ-CB 3.75Å; F297-L368 HydrophobicContact CZ-CD1 3.9Å; F297-L368 HydrophobicContact CZ-CG 4.26Å; F297-F371 HydrophobicContact CB-CD2 3.98Å; F297-F371 HydrophobicContact CB-CE2 3.62Å; F297-F371 HydrophobicContact CB-CZ 4.36Å; F297-F371 HydrophobicContact CG-CD2 4.27Å; F297-F371 HydrophobicContact CG-CE2 4.37Å
298	I	89.4	Confident	87.4	Confident	76 Å²	76	44.6 Å²	44.6	39%	0.39	24%	0.235	S	C	.	.	I	π-helix	trans	-65.3	-54.4	-174.1	-58.6	176.4	0	0	0	110.5	L293 L302	L293-I298 HydrophobicContact CG-CD1 4.32Å; L293-I298 HydrophobicContact CG-CG1 4.49Å; L293-I298 PolarHBondContact O-N 3.16Å; I298-L302 HydrophobicContact CG2-CD1 3.94Å; I298-L302 WeakPolarHBondContact O-CB 3.36Å; I298-L302 WeakPolarHBondContact O-CG 3.21Å; I298-L302 PolarHBondContact O-N 3.45Å; I298-L302 VanDerWaalsContact O-N 3.08Å
299	I	92.4	Very high	88.1	Confident	78 Å²	78	45.9 Å²	45.9	40%	0.4	24%	0.243	S	C	.	.	H	α-helix	trans	-66.6	-53.8	-176.3	-64.2	167.2	0	0	0	111.2	W223 S294 G301 L302 I303	W223-I299 HydrophobicContact CH2-CG2 3.97Å; S294-I299 WeakPolarHBondContact O-CB 3.3Å; S294-I299 WeakPolarHBondContact O-CG1 3.32Å; S294-I299 PolarHBondContact O-N 3.48Å; I299-G301 PolarHBondContact O-N 3.5Å; I299-L302 PolarHBondContact O-N 3.11Å; I299-I303 HydrophobicContact CG2-CD1 3.75Å; I299-I303 WeakPolarHBondContact O-CD1 3.35Å; I299-I303 VanDerWaalsContact O-CG1 3.25Å; I299-I303 WeakPolarHBondContact O-CG1 3.33Å; I299-I303 PolarHBondContact O-N 3.34Å; I299-I303 VanDerWaalsContact O-N 3.16Å
300	P	91.5	Very high	88.8	Confident	1 Å²	1	47.1 Å²	47.1	1%	0.006	25%	0.253	C	S	.	.	H	α-helix	trans	-58	-45.6	177.9	-28.7	39	0	0	0	112.9	E222 W223 V226 I295 L302 I303 V304	E222-P300 HydrophobicContact CG-CB 3.91Å; E222-P300 HydrophobicContact CG-CG 4.27Å; E222-P300 VanDerWaalsContact OE1-CB 3.26Å; E222-P300 WeakPolarHBondContact OE1-CB 3.37Å; W223-P300 HydrophobicContact CH2-CG 4.33Å; W223-P300 HydrophobicContact CZ2-CG 4.04Å; V226-P300 HydrophobicContact CG2-CB 3.61Å; I295-P300 WeakPolarHBondContact O-CD 3.45Å; I295-P300 WeakPolarHBondContact O-CG 3.34Å; P300-L302 PolarHBondContact O-N 3.08Å; P300-I303 PolarHBondContact O-N 2.91Å; P300-V304 WeakPolarHBondContact O-CG2 3.18Å; P300-V304 PolarHBondContact O-N 3.45Å
301	G	88.7	Confident	89	Confident	4 Å²	4	42.6 Å²	42.6	4%	0.041	23%	0.229	C	C	.	.	H	α-helix	trans	-62.2	-45.7	-177.5	0	0	0	0	0	113.1	F297 I299 I303 V304 I305 L364	F297-G301 WeakPolarHBondContact O-CA 3.38Å; F297-G301 PolarHBondContact O-N 3.21Å; I299-G301 PolarHBondContact O-N 3.5Å; G301-I303 VanDerWaalsContact C-N 3.35Å; G301-I303 PolarHBondContact O-N 3.22Å; G301-V304 PolarHBondContact O-N 2.95Å; G301-I305 VanDerWaalsContact O-CG1 3.28Å; G301-I305 WeakPolarHBondContact O-CG1 3.2Å; G301-I305 PolarHBondContact O-N 3.24Å; G301-L364 VanDerWaalsContact CA-CD2 3.44Å
302	L	91.3	Very high	89.2	Confident	97 Å²	97	40.5 Å²	40.5	51%	0.508	22%	0.216	S	C	.	.	H	α-helix	trans	-61.6	-43.2	176	-72.5	175.3	0	0	0	111.7	I298 I299 P300 V304 I305 I306	I298-L302 HydrophobicContact CG2-CD1 3.94Å; I298-L302 WeakPolarHBondContact O-CB 3.36Å; I298-L302 WeakPolarHBondContact O-CG 3.21Å; I298-L302 PolarHBondContact O-N 3.45Å; I298-L302 VanDerWaalsContact O-N 3.08Å; I299-L302 PolarHBondContact O-N 3.11Å; P300-L302 PolarHBondContact O-N 3.08Å; L302-V304 PolarHBondContact O-N 3.32Å; L302-I305 PolarHBondContact O-N 2.94Å; L302-I306 WeakPolarHBondContact O-CB 3.43Å; L302-I306 WeakPolarHBondContact O-CD1 3.46Å; L302-I306 WeakPolarHBondContact O-CG1 3.06Å; L302-I306 PolarHBondContact O-N 2.9Å
303	I	94.1	Very high	89.6	Confident	54 Å²	54	43.5 Å²	43.5	28%	0.277	23%	0.232	S	C	.	.	H	α-helix	trans	-63.2	-43.8	179	-65.2	167.4	0	0	0	110.8	V226 I230 I299 P300 G301 S307	V226-I303 HydrophobicContact CG1-CB 3.96Å; V226-I303 HydrophobicContact CG1-CD1 4.24Å; V226-I303 HydrophobicContact CG1-CG2 3.51Å; I230-I303 HydrophobicContact CD1-CG2 3.77Å; I230-I303 HydrophobicContact CG1-CG2 3.73Å; I299-I303 HydrophobicContact CG2-CD1 3.75Å; I299-I303 WeakPolarHBondContact O-CD1 3.35Å; I299-I303 VanDerWaalsContact O-CG1 3.25Å; I299-I303 WeakPolarHBondContact O-CG1 3.33Å; I299-I303 PolarHBondContact O-N 3.34Å; I299-I303 VanDerWaalsContact O-N 3.16Å; P300-I303 PolarHBondContact O-N 2.91Å; G301-I303 VanDerWaalsContact C-N 3.35Å; G301-I303 PolarHBondContact O-N 3.22Å; I303-S307 WeakPolarHBondContact O-CB 3.21Å; I303-S307 PolarHBondContact O-N 3.42Å; I303-S307 PolarHBondContact O-OG 3.46Å
304	V	90.7	Very high	89.8	Confident	6 Å²	6	43.6 Å²	43.6	4%	0.036	23%	0.234	C	C	.	.	H	α-helix	trans	-64.2	-45.8	178.2	172.7	0	0	0	0	111	F225 V226 P300 G301 L302 S307 T308 A360	F225-V304 HydrophobicContact CD1-CG2 4.08Å; F225-V304 HydrophobicContact CE1-CG1 3.84Å; F225-V304 HydrophobicContact CE1-CG2 4.1Å; V226-V304 HydrophobicContact CB-CG2 4.35Å; V226-V304 HydrophobicContact CG2-CG2 3.75Å; P300-V304 WeakPolarHBondContact O-CG2 3.18Å; P300-V304 PolarHBondContact O-N 3.45Å; G301-V304 PolarHBondContact O-N 2.95Å; L302-V304 PolarHBondContact O-N 3.32Å; V304-S307 WeakPolarHBondContact CA-OG 3.31Å; V304-S307 PolarHBondContact O-OG 3.05Å; V304-T308 HydrophobicContact CG1-CG2 4.27Å; V304-T308 WeakPolarHBondContact O-CB 3.36Å; V304-T308 VanDerWaalsContact O-CG2 3.24Å; V304-T308 WeakPolarHBondContact O-CG2 3.48Å; V304-T308 PolarHBondContact O-N 2.94Å; V304-T308 PolarHBondContact O-OG1 3.23Å; V304-A360 HydrophobicContact CG1-CB 3.42Å; V304-A360 VanDerWaalsContact CG1-CB 3.42Å
305	I	89.4	Confident	89.7	Confident	65 Å²	65	41.9 Å²	41.9	33%	0.333	22%	0.221	S	C	.	.	H	α-helix	trans	-62.3	-50.1	178.5	-67.6	166.5	0	0	0	110.5	G301 L302 S307 T308 V309 L364	G301-I305 VanDerWaalsContact O-CG1 3.28Å; G301-I305 WeakPolarHBondContact O-CG1 3.2Å; G301-I305 PolarHBondContact O-N 3.24Å; L302-I305 PolarHBondContact O-N 2.94Å; I305-S307 PolarHBondContact O-N 3.16Å; I305-T308 PolarHBondContact O-N 3.39Å; I305-T308 PolarHBondContact O-OG1 2.89Å; I305-V309 HydrophobicContact CG2-CG2 4.22Å; I305-V309 WeakPolarHBondContact O-CB 3.28Å; I305-V309 WeakPolarHBondContact O-CG2 3.38Å; I305-V309 PolarHBondContact O-N 3.16Å; I305-L364 HydrophobicContact CD1-CD1 3.74Å; I305-L364 HydrophobicContact CG1-CD1 4.09Å
306	I	92.3	Very high	89.7	Confident	102 Å²	102	42.7 Å²	42.7	52%	0.523	23%	0.225	S	C	.	.	H	α-helix	trans	-60.9	-48	-179.2	-68	166.3	0	0	0	110.4	L302 T308 L310	L302-I306 WeakPolarHBondContact O-CB 3.43Å; L302-I306 WeakPolarHBondContact O-CD1 3.46Å; L302-I306 WeakPolarHBondContact O-CG1 3.06Å; L302-I306 PolarHBondContact O-N 2.9Å; I306-T308 PolarHBondContact O-N 3.43Å; I306-L310 HydrophobicContact CG2-CD1 3.8Å; I306-L310 HydrophobicContact CG2-CG 4.37Å; I306-L310 WeakPolarHBondContact O-CB 3.46Å; I306-L310 WeakPolarHBondContact O-CG 3.31Å; I306-L310 PolarHBondContact O-N 3.5Å
307	S	92	Very high	89.9	Confident	8 Å²	8	49 Å²	49	6%	0.056	25%	0.252	C	S	.	.	H	α-helix	trans	-64.2	-40.9	-178.6	59.6	0	0	0	0	112.8	C229 C233 I303 V304 I305 M311	C229-S307 WeakPolarHBondContact CB-OG 3.36Å; C233-S307 PolarHBondContact SG-O 2.95Å; I303-S307 WeakPolarHBondContact O-CB 3.21Å; I303-S307 PolarHBondContact O-N 3.42Å; I303-S307 PolarHBondContact O-OG 3.46Å; V304-S307 WeakPolarHBondContact CA-OG 3.31Å; V304-S307 PolarHBondContact O-OG 3.05Å; I305-S307 PolarHBondContact O-N 3.16Å; S307-M311 PolarHBondContact O-N 3.31Å
308	T	87.7	Confident	89.7	Confident	3 Å²	3	53.3 Å²	53.3	2%	0.018	27%	0.268	C	S	.	.	H	α-helix	trans	-71.6	-41.6	178.7	52.6	0	0	0	0	112.5	V304 I305 I306 M311 I312 L357	V304-T308 HydrophobicContact CG1-CG2 4.27Å; V304-T308 WeakPolarHBondContact O-CB 3.36Å; V304-T308 VanDerWaalsContact O-CG2 3.24Å; V304-T308 WeakPolarHBondContact O-CG2 3.48Å; V304-T308 PolarHBondContact O-N 2.94Å; V304-T308 PolarHBondContact O-OG1 3.23Å; I305-T308 PolarHBondContact O-N 3.39Å; I305-T308 PolarHBondContact O-OG1 2.89Å; I306-T308 PolarHBondContact O-N 3.43Å; T308-M311 WeakPolarHBondContact O-CB 3.39Å; T308-M311 PolarHBondContact O-N 2.78Å; T308-I312 VanDerWaalsContact O-CG1 3.3Å; T308-I312 WeakPolarHBondContact O-CG1 3.36Å; T308-I312 PolarHBondContact O-N 2.9Å; T308-L357 WeakPolarHBondContact OG1-CD1 3.48Å
309	V	90	Very high	89.5	Confident	60 Å²	60	53.9 Å²	53.9	36%	0.364	27%	0.267	S	S	.	.	H	α-helix	trans	-62	-45.7	174.7	170.7	0	0	0	0	110.6	I305 M311 I312 I313	I305-V309 HydrophobicContact CG2-CG2 4.22Å; I305-V309 WeakPolarHBondContact O-CB 3.28Å; I305-V309 WeakPolarHBondContact O-CG2 3.38Å; I305-V309 PolarHBondContact O-N 3.16Å; V309-M311 PolarHBondContact O-N 3.09Å; V309-I312 PolarHBondContact O-N 3.33Å; V309-I313 HydrophobicContact CG1-CD1 3.78Å; V309-I313 HydrophobicContact CG1-CG1 4.42Å; V309-I313 VanDerWaalsContact O-CG1 3.32Å; V309-I313 WeakPolarHBondContact O-CG1 3.41Å; V309-I313 PolarHBondContact O-N 3.06Å
310	L	92.3	Very high	89.2	Confident	74 Å²	74	55 Å²	55	39%	0.387	27%	0.274	S	S	.	.	H	α-helix	trans	-58.3	-45.9	174.9	-74.9	173.2	0	0	0	111.7	I306 I312 I313 V314	I306-L310 HydrophobicContact CG2-CD1 3.8Å; I306-L310 HydrophobicContact CG2-CG 4.37Å; I306-L310 WeakPolarHBondContact O-CB 3.46Å; I306-L310 WeakPolarHBondContact O-CG 3.31Å; I306-L310 PolarHBondContact O-N 3.5Å; L310-I312 PolarHBondContact O-N 3.06Å; L310-I313 PolarHBondContact O-N 2.85Å; L310-V314 VanDerWaalsContact O-CG2 3.23Å; L310-V314 WeakPolarHBondContact O-CG2 3.47Å; L310-V314 PolarHBondContact O-N 3.28Å
311	M	88.3	Confident	88.9	Confident	3 Å²	3	61.3 Å²	61.3	2%	0.015	30%	0.301	C	S	.	.	H	α-helix	trans	-55.5	-48	174.2	-89.3	-176.1	36.2	0	0	112.4	R232 C233 I236 S307 T308 V309 V314 L315 A353 M356	R232-M311 HydrophobicContact CB-SD 3.75Å; C233-M311 HydrophobicContact CB-CG 3.85Å; C233-M311 HydrophobicContact CB-SD 4.28Å; I236-M311 HydrophobicContact CD1-CB 4.4Å; I236-M311 HydrophobicContact CD1-CE 3.69Å; I236-M311 HydrophobicContact CD1-CG 3.7Å; I236-M311 HydrophobicContact CD1-SD 3.78Å; S307-M311 PolarHBondContact O-N 3.31Å; T308-M311 WeakPolarHBondContact O-CB 3.39Å; T308-M311 PolarHBondContact O-N 2.78Å; V309-M311 PolarHBondContact O-N 3.09Å; M311-V314 PolarHBondContact O-N 3.41Å; M311-L315 WeakPolarHBondContact O-CB 3.31Å; M311-L315 VanDerWaalsContact O-CG 3.25Å; M311-L315 WeakPolarHBondContact O-CG 3.26Å; M311-L315 PolarHBondContact O-N 3.21Å; M311-A353 HydrophobicContact CE-CB 3.93Å; M311-M356 HydrophobicContact CE-CE 3.94Å
312	I	88	Confident	88.3	Confident	24 Å²	24	63 Å²	63	12%	0.123	31%	0.312	C	S	.	.	H	α-helix	trans	-62.5	-46.3	-178.6	-69.7	165.1	0	0	0	110.4	T308 V309 L310 V314 L315 I316 A353 L357	T308-I312 VanDerWaalsContact O-CG1 3.3Å; T308-I312 WeakPolarHBondContact O-CG1 3.36Å; T308-I312 PolarHBondContact O-N 2.9Å; V309-I312 PolarHBondContact O-N 3.33Å; L310-I312 PolarHBondContact O-N 3.06Å; I312-V314 VanDerWaalsContact C-N 3.34Å; I312-V314 PolarHBondContact O-N 3.03Å; I312-L315 PolarHBondContact O-N 3.22Å; I312-I316 HydrophobicContact CG2-CD1 3.6Å; I312-I316 HydrophobicContact CG2-CG1 4.31Å; I312-I316 WeakPolarHBondContact O-CB 3.41Å; I312-I316 VanDerWaalsContact O-CG1 3.26Å; I312-I316 WeakPolarHBondContact O-CG1 3.41Å; I312-I316 PolarHBondContact O-N 3.35Å; I312-A353 HydrophobicContact CG1-CB 3.91Å; I312-L357 HydrophobicContact CD1-CB 4.31Å; I312-L357 HydrophobicContact CD1-CD2 3.78Å
313	I	91.3	Very high	87.7	Confident	77 Å²	77	60.4 Å²	60.4	40%	0.395	31%	0.305	S	S	.	.	H	α-helix	trans	-58.5	-46.6	178.3	-68.2	166.9	0	0	0	110.7	V309 L310 I316 K317	V309-I313 HydrophobicContact CG1-CD1 3.78Å; V309-I313 HydrophobicContact CG1-CG1 4.42Å; V309-I313 VanDerWaalsContact O-CG1 3.32Å; V309-I313 WeakPolarHBondContact O-CG1 3.41Å; V309-I313 PolarHBondContact O-N 3.06Å; L310-I313 PolarHBondContact O-N 2.85Å; I313-I316 PolarHBondContact O-N 3.29Å; I313-K317 HydrophobicContact CG2-CD 4.25Å; I313-K317 WeakPolarHBondContact O-CB 3.27Å; I313-K317 WeakPolarHBondContact O-CG 3.45Å; I313-K317 PolarHBondContact O-N 3.22Å
314	V	89.1	Confident	87.1	Confident	40 Å²	40	65 Å²	65	24%	0.242	32%	0.323	C	S	.	.	H	α-helix	trans	-64.9	-43.9	-179.8	175.9	0	0	0	0	111.1	I236 L237 L310 M311 I312 K317 W318	I236-V314 HydrophobicContact CG2-CB 4.01Å; I236-V314 HydrophobicContact CG2-CG1 3.59Å; L237-V314 HydrophobicContact CD2-CG2 3.49Å; L237-V314 VanDerWaalsContact CD2-CG2 3.49Å; L237-V314 HydrophobicContact CG-CG2 4.39Å; L310-V314 VanDerWaalsContact O-CG2 3.23Å; L310-V314 WeakPolarHBondContact O-CG2 3.47Å; L310-V314 PolarHBondContact O-N 3.28Å; M311-V314 PolarHBondContact O-N 3.41Å; I312-V314 VanDerWaalsContact C-N 3.34Å; I312-V314 PolarHBondContact O-N 3.03Å; V314-K317 PolarHBondContact O-N 2.98Å; V314-W318 WeakPolarHBondContact O-CB 3.25Å; V314-W318 PolarHBondContact O-N 3.31Å
315	L	86.1	Confident	86.4	Confident	3 Å²	3	70.3 Å²	70.3	2%	0.016	35%	0.345	C	S	.	.	H	α-helix	trans	-64.6	-40	178.3	-72.9	171	0	0	0	112.3	I236 M311 I312 W318 K319 R349 I350 A353	I236-L315 HydrophobicContact CD1-CD1 4.36Å; I236-L315 HydrophobicContact CG2-CD2 4.45Å; I236-L315 HydrophobicContact CG2-CG 4.4Å; M311-L315 WeakPolarHBondContact O-CB 3.31Å; M311-L315 VanDerWaalsContact O-CG 3.25Å; M311-L315 WeakPolarHBondContact O-CG 3.26Å; M311-L315 PolarHBondContact O-N 3.21Å; I312-L315 PolarHBondContact O-N 3.22Å; L315-W318 HydrophobicContact CD2-CE3 4.24Å; L315-W318 PolarHBondContact O-N 2.86Å; L315-K319 WeakPolarHBondContact O-CB 3.38Å; L315-K319 PolarHBondContact O-N 2.88Å; L315-R349 HydrophobicContact CD2-CB 4.42Å; L315-I350 HydrophobicContact CB-CG1 3.87Å; L315-I350 HydrophobicContact CD1-CG1 4.45Å; L315-A353 HydrophobicContact CD1-CB 4.06Å
316	I	87.4	Confident	85.6	Confident	75 Å²	75	69.6 Å²	69.6	39%	0.385	34%	0.341	S	S	.	.	H	α-helix	trans	-64.7	-47.6	174.7	-69.2	168.8	0	0	0	110.3	I312 I313 W318 K319 L320	I312-I316 HydrophobicContact CG2-CD1 3.6Å; I312-I316 HydrophobicContact CG2-CG1 4.31Å; I312-I316 WeakPolarHBondContact O-CB 3.41Å; I312-I316 VanDerWaalsContact O-CG1 3.26Å; I312-I316 WeakPolarHBondContact O-CG1 3.41Å; I312-I316 PolarHBondContact O-N 3.35Å; I313-I316 PolarHBondContact O-N 3.29Å; I316-W318 VanDerWaalsContact C-N 3.26Å; I316-W318 PolarHBondContact O-N 3.46Å; I316-K319 PolarHBondContact O-N 3.36Å; I316-L320 HydrophobicContact CG2-CD1 3.89Å; I316-L320 HydrophobicContact CG2-CG 4.37Å; I316-L320 WeakPolarHBondContact O-CB 3.33Å; I316-L320 WeakPolarHBondContact O-CG 3.3Å; I316-L320 PolarHBondContact O-N 2.99Å
317	K	88.8	Confident	84.7	Confident	144 Å²	144	70.1 Å²	70.1	63%	0.626	34%	0.344	S	S	*	.	H	α-helix	trans	-57.2	-41.1	175.5	-79.2	-177.2	176.2	-179.2	0	111.5	I313 V314 L320 K321	I313-K317 HydrophobicContact CG2-CD 4.25Å; I313-K317 WeakPolarHBondContact O-CB 3.27Å; I313-K317 WeakPolarHBondContact O-CG 3.45Å; I313-K317 PolarHBondContact O-N 3.22Å; V314-K317 PolarHBondContact O-N 2.98Å; K317-L320 PolarHBondContact O-N 3.44Å; K317-K321 WeakPolarHBondContact O-CB 3.46Å; K317-K321 PolarHBondContact O-N 3.02Å
318	W	83.9	Confident	84	Confident	126 Å²	126	74.2 Å²	74.2	48%	0.477	36%	0.364	S	S	.	.	H	α-helix	trans	-67.2	-43.5	177.8	-171.2	25.1	0	0	0	112.3	V314 L315 I316 L320 K321 S322	V314-W318 WeakPolarHBondContact O-CB 3.25Å; V314-W318 PolarHBondContact O-N 3.31Å; L315-W318 HydrophobicContact CD2-CE3 4.24Å; L315-W318 PolarHBondContact O-N 2.86Å; I316-W318 VanDerWaalsContact C-N 3.26Å; I316-W318 PolarHBondContact O-N 3.46Å; W318-L320 PolarHBondContact O-N 2.95Å; W318-K321 PolarHBondContact O-N 3.37Å; W318-S322 PolarHBondContact O-N 2.95Å
319	K	83.9	Confident	83	Confident	88 Å²	88	78.6 Å²	78.6	38%	0.383	39%	0.387	S	S	.	.	H	α-helix	trans	-59.2	-45.7	174.2	-174.4	178	178.5	-179.3	0	111.7	L315 I316 S322 A323 T346 I350	L315-K319 WeakPolarHBondContact O-CB 3.38Å; L315-K319 PolarHBondContact O-N 2.88Å; I316-K319 PolarHBondContact O-N 3.36Å; K319-S322 PolarHBondContact O-N 3.29Å; K319-A323 PolarHBondContact O-N 3.14Å; K319-T346 HydrophobicContact CB-CG2 4.13Å; K319-I350 HydrophobicContact CB-CD1 4.23Å; K319-I350 HydrophobicContact CD-CD1 3.68Å
320	L	85.7	Confident	81.7	Confident	102 Å²	102	80.5 Å²	80.5	53%	0.534	40%	0.396	S	S	.	.	H	α-helix	trans	-62.8	-42.5	176.9	-72.3	169.3	0	0	0	111.9	I316 K317 W318 A323 K324	I316-L320 HydrophobicContact CG2-CD1 3.89Å; I316-L320 HydrophobicContact CG2-CG 4.37Å; I316-L320 WeakPolarHBondContact O-CB 3.33Å; I316-L320 WeakPolarHBondContact O-CG 3.3Å; I316-L320 PolarHBondContact O-N 2.99Å; K317-L320 PolarHBondContact O-N 3.44Å; W318-L320 PolarHBondContact O-N 2.95Å; L320-A323 PolarHBondContact O-N 2.84Å; L320-K324 WeakPolarHBondContact O-CG 3.35Å; L320-K324 PolarHBondContact O-N 3.16Å
321	K	85.6	Confident	80.4	Confident	132 Å²	132	85.1 Å²	85.1	57%	0.574	41%	0.413	S	S	*	.	H	α-helix	trans	-61.9	-45	175.8	-174.5	172.5	179.2	176.8	0	111	K317 W318 K324 F325	K317-K321 WeakPolarHBondContact O-CB 3.46Å; K317-K321 PolarHBondContact O-N 3.02Å; W318-K321 PolarHBondContact O-N 3.37Å; K321-K324 PolarHBondContact O-N 3.29Å; K321-F325 HydrophobicContact CD-CE2 4.24Å; K321-F325 HydrophobicContact CG-CD2 3.92Å; K321-F325 HydrophobicContact CG-CE2 3.66Å; K321-F325 WeakPolarHBondContact O-CD2 3.2Å; K321-F325 PolarHBondContact O-N 2.91Å; K321-F325 VanDerWaalsContact O-N 3.08Å
322	S	77.1	Confident	79.1	Confident	41 Å²	41	93.2 Å²	93.2	29%	0.287	45%	0.45	S	S	.	.	H	α-helix	trans	-61.8	-44.3	177.9	-163.9	0	0	0	0	112.4	W318 K319 K324 F325 E326	W318-S322 PolarHBondContact O-N 2.95Å; K319-S322 PolarHBondContact O-N 3.29Å; S322-K324 VanDerWaalsContact C-N 3.34Å; S322-K324 PolarHBondContact O-N 3.31Å; S322-F325 PolarHBondContact O-N 3Å; S322-E326 PolarHBondContact O-N 3.37Å
323	A	78.1	Confident	77.5	Confident	42 Å²	42	94.9 Å²	94.9	35%	0.347	46%	0.464	S	S	.	.	H	α-helix	trans	-63.6	-38.2	177.3	0	0	0	0	0	112.4	K319 L320 E326 L327	K319-A323 PolarHBondContact O-N 3.14Å; L320-A323 PolarHBondContact O-N 2.84Å; A323-E326 PolarHBondContact O-N 3.34Å; A323-L327 WeakPolarHBondContact O-CB 3.44Å; A323-L327 PolarHBondContact O-N 3.39Å
324	K	82	Confident	75.8	Confident	151 Å²	151	99.7 Å²	99.7	66%	0.657	49%	0.49	S	S	*	.	H	α-helix	trans	-63.2	-42.6	173.8	-74.4	-178	179.2	-170.8	0	112.2	L320 K321 S322 L327 I328	L320-K324 WeakPolarHBondContact O-CG 3.35Å; L320-K324 PolarHBondContact O-N 3.16Å; K321-K324 PolarHBondContact O-N 3.29Å; S322-K324 VanDerWaalsContact C-N 3.34Å; S322-K324 PolarHBondContact O-N 3.31Å; K324-L327 PolarHBondContact O-N 2.74Å; K324-I328 VanDerWaalsContact O-CG1 3.31Å; K324-I328 WeakPolarHBondContact O-CG1 3.14Å; K324-I328 PolarHBondContact O-N 3.27Å; K324-I328 VanDerWaalsContact O-N 3.08Å
325	F	75.4	Confident	74	Confident	116 Å²	116	106.2 Å²	106.2	51%	0.509	52%	0.518	S	S	.	.	H	α-helix	trans	-64.4	-40.4	176.7	-85.7	-70.3	0	0	0	112.6	K321 S322 I328 N329	K321-F325 HydrophobicContact CD-CE2 4.24Å; K321-F325 HydrophobicContact CG-CD2 3.92Å; K321-F325 HydrophobicContact CG-CE2 3.66Å; K321-F325 WeakPolarHBondContact O-CD2 3.2Å; K321-F325 PolarHBondContact O-N 2.91Å; K321-F325 VanDerWaalsContact O-N 3.08Å; S322-F325 PolarHBondContact O-N 3Å; F325-I328 PolarHBondContact O-N 3.46Å; F325-N329 WeakPolarHBondContact O-CB 3.31Å; F325-N329 PolarHBondContact O-N 3.29Å
326	E	72.4	Confident	72	Confident	51 Å²	51	108.7 Å²	108.7	24%	0.238	54%	0.544	C	S	.	.	H	α-helix	trans	-64.1	-41.1	175.9	-171.5	175.5	-152	0	0	111.8	S322 A323 I328 N329 N330 H343	S322-E326 PolarHBondContact O-N 3.37Å; A323-E326 PolarHBondContact O-N 3.34Å; E326-I328 VanDerWaalsContact C-N 3.31Å; E326-I328 PolarHBondContact O-N 3.35Å; E326-N329 PolarHBondContact O-N 2.94Å; E326-N330 VanDerWaalsContact O-CB 3.31Å; E326-N330 WeakPolarHBondContact O-CB 3.44Å; E326-N330 PolarHBondContact O-N 2.92Å; E326-N330 PolarHBondContact O-OD1 3.44Å; E326-H343 IonicContact OE1-NE2 2.66Å; E326-H343 IonicContact OE2-CD2 3.99Å; E326-H343 PolarHBondContact OE2-CD2 2.9Å; E326-H343 IonicContact OE2-CE1 3.45Å; E326-H343 IonicContact OE2-NE2 3Å; E326-H343 PolarHBondContact OE2-NE2 2.82Å
327	L	74.6	Confident	70.2	Confident	112 Å²	112	112.6 Å²	112.6	59%	0.586	57%	0.566	S	S	*	*	H	α-helix	trans	-65.9	-32.7	177	-167.1	133.6	0	0	0	112.9	A323 K324 K331	A323-L327 WeakPolarHBondContact O-CB 3.44Å; A323-L327 PolarHBondContact O-N 3.39Å; K324-L327 PolarHBondContact O-N 2.74Å; L327-K331 WeakPolarHBondContact O-CG 3.41Å
328	I	76.8	Confident	68.5	Low	95 Å²	95	114.6 Å²	114.6	49%	0.487	58%	0.577	S	S	.	*	H	α-helix	trans	-72.7	-43.5	173.9	-66	165.4	0	0	0	110.7	K324 F325 E326 K331	K324-I328 VanDerWaalsContact O-CG1 3.31Å; K324-I328 WeakPolarHBondContact O-CG1 3.14Å; K324-I328 PolarHBondContact O-N 3.27Å; K324-I328 VanDerWaalsContact O-N 3.08Å; F325-I328 PolarHBondContact O-N 3.46Å; E326-I328 VanDerWaalsContact C-N 3.31Å; E326-I328 PolarHBondContact O-N 3.35Å; I328-K331 PolarHBondContact O-N 2.88Å
329	N	67	Low	67	Low	94 Å²	94	111.8 Å²	111.8	50%	0.503	57%	0.574	S	S	.	*	H	α-helix	trans	-70.8	-34.8	-179.1	-76.6	-2.2	0	0	0	113.2	F325 E326 K331 H332 S333	F325-N329 WeakPolarHBondContact O-CB 3.31Å; F325-N329 PolarHBondContact O-N 3.29Å; E326-N329 PolarHBondContact O-N 2.94Å; N329-K331 PolarHBondContact O-N 3.45Å; N329-H332 CarbonylContact O-C 3.58Å; N329-H332 PolarHBondContact O-N 3.29Å; N329-S333 PolarHBondContact O-N 3.38Å; N329-S333 PolarHBondContact O-OG 2.83Å
330	N	62.5	Low	65.3	Low	101 Å²	101	114.8 Å²	114.8	54%	0.54	59%	0.589	S	S	.	*	H	α-helix	trans	-68.4	-24	176	-72	-4.8	0	0	0	112.1	E326 H332	E326-N330 VanDerWaalsContact O-CB 3.31Å; E326-N330 WeakPolarHBondContact O-CB 3.44Å; E326-N330 PolarHBondContact O-N 2.92Å; E326-N330 PolarHBondContact O-OD1 3.44Å; N330-H332 VanDerWaalsContact C-N 3.28Å
331	K	63.9	Low	63.7	Low	171 Å²	171	117.2 Å²	117.2	74%	0.743	60%	0.597	S	S	*	*	T	Hydrogen-bonded Turn	trans	-73.7	-19.3	170.3	-75.7	-176.9	177.2	-171.8	0	113.2	L327 I328 N329	L327-K331 WeakPolarHBondContact O-CG 3.41Å; I328-K331 PolarHBondContact O-N 2.88Å; N329-K331 PolarHBondContact O-N 3.45Å
332	H	60.9	Low	62.2	Low	173 Å²	173	114.8 Å²	114.8	80%	0.801	59%	0.594	S	S	*	*	T	Hydrogen-bonded Turn	trans	-112.6	-6.8	-175.5	-96.2	-47.6	0	0	0	115.2	N329 N330	N329-H332 CarbonylContact O-C 3.58Å; N329-H332 PolarHBondContact O-N 3.29Å; N330-H332 VanDerWaalsContact C-N 3.28Å
333	S	55.7	Low	61.1	Low	59 Å²	59	115.7 Å²	115.7	41%	0.413	59%	0.593	S	S	.	*			trans	-142.9	116.4	-177.4	60.2	0	0	0	0	112.8	N329 H335	N329-S333 PolarHBondContact O-N 3.38Å; N329-S333 PolarHBondContact O-OG 2.83Å; S333-H335 PolarHBondContact O-N 3.36Å; S333-H335 VanDerWaalsContact O-N 3.16Å
334	N	54.7	Low	60.2	Low	177 Å²	177	120.5 Å²	120.5	95%	0.947	61%	0.608	S	S	*	*			trans	-75.1	20.4	166.8	-94.7	-9	0	0	0	112.8
335	H	51.8	Low	59.4	Low	178 Å²	178	117.9 Å²	117.9	82%	0.824	60%	0.598	S	S	*	*			trans	-113.3	79.7	-179.3	-109.5	-29.6	0	0	0	111.3	S333	S333-H335 PolarHBondContact O-N 3.36Å; S333-H335 VanDerWaalsContact O-N 3.16Å
336	G	44.4	Very low	59.1	Low	55 Å²	55	113 Å²	113	57%	0.567	58%	0.578	S	S	*	*			trans	-69.4	133.5	164.9	0	0	0	0	0	110.6
337	N	50.1	Low	59.1	Low	157 Å²	157	113 Å²	113	84%	0.84	58%	0.584	S	S	*	*	S	Bend	trans	171.1	6.7	140	-86.1	-10.6	0	0	0	115.8
338	H	52.2	Low	59	Low	185 Å²	185	108.9 Å²	108.9	86%	0.856	56%	0.564	S	S	*	*	S	Bend	trans	-116.6	3.1	-178.3	-85.4	-55.2	0	0	0	117.9
339	T	51.5	Low	58.9	Low	67 Å²	67	110.8 Å²	110.8	41%	0.411	57%	0.565	S	S	.	*			trans	-96.7	-12.7	-169.1	49.8	0	0	0	0	116.5	H341 T342	T339-H341 VanDerWaalsContact C-N 3.31Å; T339-H341 PolarHBondContact O-N 3.14Å; T339-T342 PolarHBondContact O-OG1 2.95Å
340	H	49.9	Very low	59.4	Low	152 Å²	152	107.1 Å²	107.1	70%	0.704	55%	0.545	S	S	*	.	H	α-helix	trans	-65.4	-26.5	-173.6	-94.3	-75.2	0	0	0	115.1	H344	H340-H344 PolarHBondContact O-CD2 3.22Å
341	H	51.2	Low	60.2	Low	152 Å²	152	105.7 Å²	105.7	70%	0.704	54%	0.541	S	S	*	.	H	α-helix	trans	-74.8	-30.1	-174.7	-83.8	-71.9	0	0	0	114.6	T339 H345	T339-H341 VanDerWaalsContact C-N 3.31Å; T339-H341 PolarHBondContact O-N 3.14Å; H341-H345 PolarHBondContact O-CD2 3.32Å; H341-H345 VanDerWaalsContact O-CD2 3.3Å
342	T	54.8	Low	60.9	Low	82 Å²	82	98 Å²	98	50%	0.503	51%	0.507	S	S	.	.	H	α-helix	trans	-77.9	-30.9	-174.1	53.5	0	0	0	0	113.1	T339 T346	T339-T342 PolarHBondContact O-OG1 2.95Å; T342-T346 PolarHBondContact O-N 3.48Å; T342-T346 PolarHBondContact O-OG1 3.15Å
343	H	53.7	Low	61.8	Low	59 Å²	59	89.8 Å²	89.8	27%	0.273	47%	0.47	S	S	.	.	H	α-helix	trans	-67.4	-42.6	178.7	-95	-68.3	0	0	0	113.4	E326 H345 T346 S347	E326-H343 IonicContact OE1-NE2 2.66Å; E326-H343 IonicContact OE2-CD2 3.99Å; E326-H343 PolarHBondContact OE2-CD2 2.9Å; E326-H343 IonicContact OE2-CE1 3.45Å; E326-H343 IonicContact OE2-NE2 3Å; E326-H343 PolarHBondContact OE2-NE2 2.82Å; H343-H345 PolarHBondContact O-N 2.89Å; H343-T346 PolarHBondContact O-N 2.92Å; H343-S347 PolarHBondContact O-N 3.24Å
344	H	58.5	Low	63.2	Low	143 Å²	143	92.3 Å²	92.3	66%	0.662	47%	0.473	S	S	*	.	H	α-helix	trans	-63.2	-40.3	-179.4	-83	-73.5	0	0	0	112.6	H340 T346 S347 S348	H340-H344 PolarHBondContact O-CD2 3.22Å; H344-T346 PolarHBondContact O-N 3.17Å; H344-S347 PolarHBondContact O-N 3.33Å; H344-S348 PolarHBondContact O-N 3.09Å
345	H	65.7	Low	64.8	Low	96 Å²	96	87.8 Å²	87.8	44%	0.444	45%	0.449	S	S	.	.	H	α-helix	trans	-64.6	-41.1	178.9	-81.2	-68	0	0	0	112.7	H341 H343 S348 R349	H341-H345 PolarHBondContact O-CD2 3.32Å; H341-H345 VanDerWaalsContact O-CD2 3.3Å; H343-H345 PolarHBondContact O-N 2.89Å; H345-S348 PolarHBondContact O-OG 3.06Å; H345-R349 WeakPolarHBondContact O-CG 3.37Å; H345-R349 PolarHBondContact O-N 2.96Å
346	T	69.2	Low	66.3	Low	14 Å²	14	79.5 Å²	79.5	9%	0.086	41%	0.41	C	S	.	.	H	α-helix	trans	-69	-39.1	-178.9	-49.2	0	0	0	0	111.6	K319 T342 H343 H344 R349 I350	K319-T346 HydrophobicContact CB-CG2 4.13Å; T342-T346 PolarHBondContact O-N 3.48Å; T342-T346 PolarHBondContact O-OG1 3.15Å; H343-T346 PolarHBondContact O-N 2.92Å; H344-T346 PolarHBondContact O-N 3.17Å; T346-R349 PolarHBondContact O-N 3.23Å; T346-I350 HydrophobicContact CG2-CD1 4.33Å; T346-I350 WeakPolarHBondContact O-CG1 3.38Å; T346-I350 PolarHBondContact O-N 3.04Å
347	S	72.8	Confident	68.3	Low	52 Å²	52	78.6 Å²	78.6	36%	0.364	39%	0.392	S	S	.	.	H	α-helix	trans	-61.6	-46.7	176.9	-163.8	0	0	0	0	111.9	H343 H344 R349 I350 T351	H343-S347 PolarHBondContact O-N 3.24Å; H344-S347 PolarHBondContact O-N 3.33Å; S347-R349 VanDerWaalsContact C-N 3.31Å; S347-R349 PolarHBondContact O-N 3.46Å; S347-I350 PolarHBondContact O-N 3.39Å; S347-I350 VanDerWaalsContact O-N 3.12Å; S347-T351 PolarHBondContact O-N 2.96Å
348	S	71.2	Confident	70.2	Confident	25 Å²	25	75.5 Å²	75.5	18%	0.175	38%	0.375	C	S	.	.	H	α-helix	trans	-61	-36.6	177.7	69.6	0	0	0	0	113.1	H344 H345 I350 T351 V352	H344-S348 PolarHBondContact O-N 3.09Å; H345-S348 PolarHBondContact O-OG 3.06Å; S348-I350 VanDerWaalsContact C-N 3.32Å; S348-I350 PolarHBondContact O-N 2.99Å; S348-T351 PolarHBondContact O-N 3.48Å; S348-T351 PolarHBondContact O-OG1 2.87Å; S348-V352 WeakPolarHBondContact O-CB 3.48Å; S348-V352 WeakPolarHBondContact O-CG2 3.21Å; S348-V352 PolarHBondContact O-N 2.83Å
349	R	74.4	Confident	71.9	Confident	134 Å²	134	67.1 Å²	67.1	51%	0.506	34%	0.337	S	S	.	.	H	α-helix	trans	-66.7	-35.4	176.4	-71	177.1	177.2	-171.6	0.1	112.3	L315 H345 T346 S347 A353	L315-R349 HydrophobicContact CD2-CB 4.42Å; H345-R349 WeakPolarHBondContact O-CG 3.37Å; H345-R349 PolarHBondContact O-N 2.96Å; T346-R349 PolarHBondContact O-N 3.23Å; S347-R349 VanDerWaalsContact C-N 3.31Å; S347-R349 PolarHBondContact O-N 3.46Å; R349-A353 WeakPolarHBondContact O-CB 3.23Å; R349-A353 PolarHBondContact O-N 3.33Å
350	I	77.6	Confident	73.5	Confident	17 Å²	17	64 Å²	64	9%	0.087	32%	0.318	C	S	.	.	H	α-helix	trans	-69.8	-45.1	177.6	-67.2	164.3	0	0	0	110.8	L315 K319 T346 S347 S348 V352 A353 K354	L315-I350 HydrophobicContact CB-CG1 3.87Å; L315-I350 HydrophobicContact CD1-CG1 4.45Å; K319-I350 HydrophobicContact CB-CD1 4.23Å; K319-I350 HydrophobicContact CD-CD1 3.68Å; T346-I350 HydrophobicContact CG2-CD1 4.33Å; T346-I350 WeakPolarHBondContact O-CG1 3.38Å; T346-I350 PolarHBondContact O-N 3.04Å; S347-I350 PolarHBondContact O-N 3.39Å; S347-I350 VanDerWaalsContact O-N 3.12Å; S348-I350 VanDerWaalsContact C-N 3.32Å; S348-I350 PolarHBondContact O-N 2.99Å; I350-V352 PolarHBondContact O-N 3.2Å; I350-A353 PolarHBondContact O-N 2.93Å; I350-K354 HydrophobicContact CG2-CD 4.34Å; I350-K354 WeakPolarHBondContact O-CG 3.47Å; I350-K354 PolarHBondContact O-N 3.3Å
351	T	81.1	Confident	75.4	Confident	72 Å²	72	61.2 Å²	61.2	44%	0.442	31%	0.307	S	S	.	.	H	α-helix	trans	-59.9	-37.1	178.3	55.5	0	0	0	0	111.2	S347 S348 K354 L355	S347-T351 PolarHBondContact O-N 2.96Å; S348-T351 PolarHBondContact O-N 3.48Å; S348-T351 PolarHBondContact O-OG1 2.87Å; T351-K354 WeakPolarHBondContact O-CB 3.32Å; T351-K354 PolarHBondContact O-N 3.35Å; T351-L355 WeakPolarHBondContact O-CG 3.39Å; T351-L355 PolarHBondContact O-N 2.83Å
352	V	77.3	Confident	77.3	Confident	8 Å²	8	58.1 Å²	58.1	5%	0.048	30%	0.296	C	S	.	.	H	α-helix	trans	-73.2	-41.4	-179.7	173.1	0	0	0	0	112.1	S348 I350 K354 L355 M356 G418	S348-V352 WeakPolarHBondContact O-CB 3.48Å; S348-V352 WeakPolarHBondContact O-CG2 3.21Å; S348-V352 PolarHBondContact O-N 2.83Å; I350-V352 PolarHBondContact O-N 3.2Å; V352-K354 VanDerWaalsContact C-N 3.25Å; V352-K354 PolarHBondContact O-N 2.85Å; V352-L355 PolarHBondContact O-N 3.17Å; V352-M356 HydrophobicContact CG1-CE 4.13Å; V352-M356 WeakPolarHBondContact O-CB 3.46Å; V352-M356 WeakPolarHBondContact O-CG 3.23Å; V352-M356 PolarHBondContact O-N 2.84Å; V352-G418 VanDerWaalsContact CG1-CA 3.46Å; V352-G418 WeakPolarHBondContact CG2-O 3.36Å
353	A	79.6	Confident	78.8	Confident	1 Å²	1	55 Å²	55	1%	0.008	28%	0.275	C	S	.	.	H	α-helix	trans	-59.3	-39.4	171.5	0	0	0	0	0	111.6	M311 I312 L315 R349 I350 L357	M311-A353 HydrophobicContact CE-CB 3.93Å; I312-A353 HydrophobicContact CG1-CB 3.91Å; L315-A353 HydrophobicContact CD1-CB 4.06Å; R349-A353 WeakPolarHBondContact O-CB 3.23Å; R349-A353 PolarHBondContact O-N 3.33Å; I350-A353 PolarHBondContact O-N 2.93Å; A353-L357 PolarHBondContact O-N 3.42Å
354	K	85.9	Confident	80.5	Confident	113 Å²	113	53.1 Å²	53.1	49%	0.491	27%	0.266	S	S	.	.	H	α-helix	trans	-65.9	-45.7	174.6	-71.2	179.3	175.7	-168.8	0	112.6	I350 T351 V352 M356 L357 I358	I350-K354 HydrophobicContact CG2-CD 4.34Å; I350-K354 WeakPolarHBondContact O-CG 3.47Å; I350-K354 PolarHBondContact O-N 3.3Å; T351-K354 WeakPolarHBondContact O-CB 3.32Å; T351-K354 PolarHBondContact O-N 3.35Å; V352-K354 VanDerWaalsContact C-N 3.25Å; V352-K354 PolarHBondContact O-N 2.85Å; K354-M356 VanDerWaalsContact C-N 3.33Å; K354-M356 PolarHBondContact O-N 2.79Å; K354-L357 WeakPolarHBondContact O-CB 3.5Å; K354-L357 PolarHBondContact O-N 2.92Å; K354-I358 WeakPolarHBondContact O-CG1 3.44Å; K354-I358 PolarHBondContact O-N 3.41Å
355	L	87	Confident	82	Confident	81 Å²	81	52.4 Å²	52.4	42%	0.424	26%	0.262	S	S	.	.	H	α-helix	trans	-62.5	-40.5	177.7	-73.7	171.2	0	0	0	111.7	T351 V352 I358 C359 V414	T351-L355 WeakPolarHBondContact O-CG 3.39Å; T351-L355 PolarHBondContact O-N 2.83Å; V352-L355 PolarHBondContact O-N 3.17Å; L355-I358 PolarHBondContact O-N 3Å; L355-C359 PolarHBondContact O-N 3.21Å; L355-C359 PolarHBondContact O-SG 3.43Å; L355-V414 HydrophobicContact CB-CG1 3.7Å
356	M	83.8	Confident	83.2	Confident	4 Å²	4	48.5 Å²	48.5	2%	0.02	24%	0.244	C	C	.	.	H	α-helix	trans	-63.9	-39.7	174.3	-72.6	-172.3	-62	0	0	112.2	R232 M311 V352 K354 C359 A360 V414 L415	R232-M356 PolarHBondContact NH1-SD 2.89Å; M311-M356 HydrophobicContact CE-CE 3.94Å; V352-M356 HydrophobicContact CG1-CE 4.13Å; V352-M356 WeakPolarHBondContact O-CB 3.46Å; V352-M356 WeakPolarHBondContact O-CG 3.23Å; V352-M356 PolarHBondContact O-N 2.84Å; K354-M356 VanDerWaalsContact C-N 3.33Å; K354-M356 PolarHBondContact O-N 2.79Å; M356-C359 PolarHBondContact O-N 3.38Å; M356-A360 WeakPolarHBondContact O-CB 3.25Å; M356-A360 PolarHBondContact O-N 2.72Å; M356-V414 HydrophobicContact CG-CG1 4Å; M356-L415 HydrophobicContact SD-CD2 3.65Å
357	L	87.2	Confident	84.1	Confident	37 Å²	37	48.6 Å²	48.6	19%	0.194	24%	0.244	C	C	.	.	H	α-helix	trans	-61.6	-44.3	174	177.6	68.5	0	0	0	111.1	T308 I312 A353 K354 A360 I361	T308-L357 WeakPolarHBondContact OG1-CD1 3.48Å; I312-L357 HydrophobicContact CD1-CB 4.31Å; I312-L357 HydrophobicContact CD1-CD2 3.78Å; A353-L357 PolarHBondContact O-N 3.42Å; K354-L357 WeakPolarHBondContact O-CB 3.5Å; K354-L357 PolarHBondContact O-N 2.92Å; L357-A360 PolarHBondContact O-N 3.32Å; L357-I361 HydrophobicContact CD1-CD1 4.17Å; L357-I361 HydrophobicContact CD1-CG1 4.44Å; L357-I361 HydrophobicContact CG-CD1 3.95Å; L357-I361 VanDerWaalsContact O-CG1 3.3Å; L357-I361 WeakPolarHBondContact O-CG1 3.46Å; L357-I361 PolarHBondContact O-N 3.28Å
358	I	89.4	Confident	84.8	Confident	91 Å²	91	49.6 Å²	49.6	47%	0.467	25%	0.245	S	C	.	.	H	α-helix	trans	-61.4	-45.7	177	-66.5	163.8	0	0	0	110.4	K354 L355 A360 I361 L362	K354-I358 WeakPolarHBondContact O-CG1 3.44Å; K354-I358 PolarHBondContact O-N 3.41Å; L355-I358 PolarHBondContact O-N 3Å; I358-A360 VanDerWaalsContact C-N 3.33Å; I358-A360 PolarHBondContact O-N 2.72Å; I358-I361 PolarHBondContact O-N 3.39Å; I358-L362 HydrophobicContact CG2-CD1 3.91Å; I358-L362 HydrophobicContact CG2-CG 4.41Å; I358-L362 WeakPolarHBondContact O-CG 3.32Å; I358-L362 PolarHBondContact O-N 2.89Å
359	C	87.6	Confident	85.7	Confident	9 Å²	9	49.7 Å²	49.7	6%	0.061	25%	0.245	C	C	.	.	H	α-helix	trans	-61.5	-41.9	176.9	-64.7	0	0	0	0	111.8	L355 M356 L362 Y363	L355-C359 PolarHBondContact O-N 3.21Å; L355-C359 PolarHBondContact O-SG 3.43Å; M356-C359 PolarHBondContact O-N 3.38Å; C359-L362 PolarHBondContact O-N 3.25Å; C359-Y363 VanDerWaalsContact O-CB 3.26Å; C359-Y363 WeakPolarHBondContact O-CB 3.46Å; C359-Y363 PolarHBondContact O-N 3.24Å
360	A	85.9	Confident	86.3	Confident	2 Å²	2	43.6 Å²	43.6	2%	0.017	22%	0.222	C	C	.	.	H	α-helix	trans	-62.8	-43.2	176.5	0	0	0	0	0	112.3	F225 V304 M356 L357 I358 Y363 L364	F225-A360 HydrophobicContact CE1-CB 4.29Å; V304-A360 HydrophobicContact CG1-CB 3.42Å; V304-A360 VanDerWaalsContact CG1-CB 3.42Å; M356-A360 WeakPolarHBondContact O-CB 3.25Å; M356-A360 PolarHBondContact O-N 2.72Å; L357-A360 PolarHBondContact O-N 3.32Å; I358-A360 VanDerWaalsContact C-N 3.33Å; I358-A360 PolarHBondContact O-N 2.72Å; A360-Y363 PolarHBondContact O-N 2.72Å; A360-L364 WeakPolarHBondContact O-CB 3.46Å; A360-L364 VanDerWaalsContact O-CG 3.25Å; A360-L364 WeakPolarHBondContact O-CG 3.33Å; A360-L364 PolarHBondContact O-N 3.34Å
361	I	89.5	Confident	86.6	Confident	94 Å²	94	42.9 Å²	42.9	48%	0.482	22%	0.219	S	C	.	.	H	α-helix	trans	-63.6	-45.1	176.6	-67.7	165.2	0	0	0	110.5	L357 I358 L364 F365	L357-I361 HydrophobicContact CD1-CD1 4.17Å; L357-I361 HydrophobicContact CD1-CG1 4.44Å; L357-I361 HydrophobicContact CG-CD1 3.95Å; L357-I361 VanDerWaalsContact O-CG1 3.3Å; L357-I361 WeakPolarHBondContact O-CG1 3.46Å; L357-I361 PolarHBondContact O-N 3.28Å; I358-I361 PolarHBondContact O-N 3.39Å; I361-L364 PolarHBondContact O-N 2.68Å; I361-F365 WeakPolarHBondContact O-CB 3.45Å; I361-F365 PolarHBondContact O-N 2.92Å
362	L	90.7	Very high	86.9	Confident	87 Å²	87	42.7 Å²	42.7	46%	0.455	22%	0.217	S	C	.	.	H	α-helix	trans	-63.6	-43.6	177.9	-70.2	170.3	0	0	0	111.5	I358 C359 F365 I366 I407	I358-L362 HydrophobicContact CG2-CD1 3.91Å; I358-L362 HydrophobicContact CG2-CG 4.41Å; I358-L362 WeakPolarHBondContact O-CG 3.32Å; I358-L362 PolarHBondContact O-N 2.89Å; C359-L362 PolarHBondContact O-N 3.25Å; L362-F365 PolarHBondContact O-N 3.39Å; L362-I366 WeakPolarHBondContact O-CG1 3.43Å; L362-I366 PolarHBondContact O-N 3.47Å; L362-I407 HydrophobicContact CB-CD1 3.78Å
363	Y	87.7	Confident	87.2	Confident	16 Å²	16	44 Å²	44	6%	0.063	22%	0.222	C	C	.	.	H	α-helix	trans	-57.3	-50.9	174.7	174.1	-94	0	0	0	111.4	E222 C359 A360 F365 I366 L367 Y404 I407 L408	E222-Y363 HydrophobicContact CG-CE1 4.38Å; C359-Y363 VanDerWaalsContact O-CB 3.26Å; C359-Y363 WeakPolarHBondContact O-CB 3.46Å; C359-Y363 PolarHBondContact O-N 3.24Å; A360-Y363 PolarHBondContact O-N 2.72Å; Y363-F365 VanDerWaalsContact C-N 3.31Å; Y363-F365 PolarHBondContact O-N 2.95Å; Y363-I366 PolarHBondContact O-N 3.39Å; Y363-L367 HydrophobicContact CE1-CD2 3.74Å; Y363-L367 WeakPolarHBondContact O-CB 3.44Å; Y363-L367 PolarHBondContact O-N 3.4Å; Y363-Y404 HydrophobicContact CD2-CD2 4.38Å; Y363-Y404 HydrophobicContact CD2-CE2 4.08Å; Y363-Y404 AromaticContact CE2-CD2 3.92Å; Y363-Y404 HydrophobicContact CE2-CD2 3.92Å; Y363-Y404 AromaticContact CE2-CE2 3.2Å; Y363-Y404 HydrophobicContact CE2-CE2 3.2Å; Y363-Y404 AromaticContact CE2-CZ 3.84Å; Y363-Y404 AromaticContact CZ-CE2 3.67Å; Y363-Y404 PolarHBondContact OH-OH 2.88Å; Y363-I407 HydrophobicContact CD2-CG2 4.43Å; Y363-L408 HydrophobicContact CD2-CD2 4.26Å; Y363-L408 HydrophobicContact CE2-CD2 3.92Å; Y363-L408 HydrophobicContact CE2-CG 4.36Å
364	L	88.6	Confident	87	Confident	19 Å²	19	44.6 Å²	44.6	10%	0.099	23%	0.229	C	C	.	.	H	α-helix	trans	-62.1	-39.6	178.1	-71.9	173.1	0	0	0	111.8	F297 G301 I305 A360 I361 L367 L368	F297-L364 HydrophobicContact CD2-CD2 3.75Å; F297-L364 HydrophobicContact CE2-CB 3.94Å; F297-L364 HydrophobicContact CE2-CD2 3.66Å; F297-L364 HydrophobicContact CE2-CG 4.4Å; F297-L364 WeakPolarHBondContact CE2-O 3.49Å; G301-L364 VanDerWaalsContact CA-CD2 3.44Å; I305-L364 HydrophobicContact CD1-CD1 3.74Å; I305-L364 HydrophobicContact CG1-CD1 4.09Å; A360-L364 WeakPolarHBondContact O-CB 3.46Å; A360-L364 VanDerWaalsContact O-CG 3.25Å; A360-L364 WeakPolarHBondContact O-CG 3.33Å; A360-L364 PolarHBondContact O-N 3.34Å; I361-L364 PolarHBondContact O-N 2.68Å; L364-L367 PolarHBondContact O-N 3.41Å; L364-L368 VanDerWaalsContact O-CB 3.25Å; L364-L368 WeakPolarHBondContact O-CB 3.37Å; L364-L368 PolarHBondContact O-N 3.49Å
365	F	91	Very high	86.7	Confident	128 Å²	128	42.6 Å²	42.6	56%	0.561	23%	0.229	S	C	*	.	H	α-helix	trans	-61.1	-48.3	176.7	178.2	-100.5	0	0	0	111.8	I361 L362 Y363 L367 L368 C369	I361-F365 WeakPolarHBondContact O-CB 3.45Å; I361-F365 PolarHBondContact O-N 2.92Å; L362-F365 PolarHBondContact O-N 3.39Å; Y363-F365 VanDerWaalsContact C-N 3.31Å; Y363-F365 PolarHBondContact O-N 2.95Å; F365-L367 VanDerWaalsContact C-N 3.34Å; F365-L367 PolarHBondContact O-N 3.29Å; F365-L368 WeakPolarHBondContact O-CB 3.42Å; F365-L368 PolarHBondContact O-N 3.41Å; F365-C369 PolarHBondContact O-N 3.36Å; F365-C369 PolarHBondContact O-SG 2.82Å
366	I	90	Very high	86.3	Confident	15 Å²	15	43.9 Å²	43.9	8%	0.077	24%	0.235	C	C	.	.	H	α-helix	trans	-63.4	-42.8	177.6	-65.3	-156.6	0	0	0	111.4	L362 Y363 L368 C369 L370 L403 I407	L362-I366 WeakPolarHBondContact O-CG1 3.43Å; L362-I366 PolarHBondContact O-N 3.47Å; Y363-I366 PolarHBondContact O-N 3.39Å; I366-L368 VanDerWaalsContact C-N 3.34Å; I366-L368 PolarHBondContact O-N 2.92Å; I366-C369 WeakPolarHBondContact O-CB 3.02Å; I366-C369 PolarHBondContact O-N 3.29Å; I366-C369 VanDerWaalsContact O-N 3.16Å; I366-L370 HydrophobicContact CG2-CD1 4.3Å; I366-L370 PolarHBondContact O-N 3Å; I366-L403 HydrophobicContact CD1-CB 3.49Å; I366-L403 VanDerWaalsContact CD1-CB 3.49Å; I366-I407 HydrophobicContact CB-CD1 4.37Å; I366-I407 HydrophobicContact CD1-CD1 3.19Å; I366-I407 HydrophobicContact CD1-CG1 3.99Å; I366-I407 HydrophobicContact CG1-CD1 3.6Å
367	L	87	Confident	85.9	Confident	16 Å²	16	47.5 Å²	47.5	8%	0.084	25%	0.249	C	C	.	.	H	α-helix	trans	-63.8	-42.7	179.6	-170.1	53.3	0	0	0	111.1	T296 F297 Y363 L364 F365 C369 L370 F371 Y404	T296-L367 WeakPolarHBondContact O-CD2 3.4Å; F297-L367 HydrophobicContact CB-CD2 4.27Å; F297-L367 HydrophobicContact CB-CG 4.46Å; F297-L367 HydrophobicContact CD2-CB 4.13Å; F297-L367 HydrophobicContact CD2-CD2 4.04Å; F297-L367 HydrophobicContact CD2-CG 4Å; Y363-L367 HydrophobicContact CE1-CD2 3.74Å; Y363-L367 WeakPolarHBondContact O-CB 3.44Å; Y363-L367 PolarHBondContact O-N 3.4Å; L364-L367 PolarHBondContact O-N 3.41Å; F365-L367 VanDerWaalsContact C-N 3.34Å; F365-L367 PolarHBondContact O-N 3.29Å; L367-C369 VanDerWaalsContact C-N 3.31Å; L367-C369 PolarHBondContact O-N 2.95Å; L367-L370 WeakPolarHBondContact O-CB 3.46Å; L367-L370 PolarHBondContact O-N 2.87Å; L367-L370 VanDerWaalsContact O-N 3.16Å; L367-F371 HydrophobicContact CD1-CD2 4.04Å; L367-F371 HydrophobicContact CD1-CE2 3.64Å; L367-F371 HydrophobicContact CD2-CE2 4.3Å; L367-F371 HydrophobicContact CG-CD2 3.88Å; L367-F371 HydrophobicContact CG-CE2 3.64Å; L367-F371 WeakPolarHBondContact O-CD2 3.36Å; L367-F371 PolarHBondContact O-N 3.42Å; L367-Y404 HydrophobicContact CD1-CE2 4.35Å
368	L	89.5	Confident	84.7	Confident	72 Å²	72	49.7 Å²	49.7	38%	0.377	26%	0.261	S	S	.	.	H	α-helix	trans	-57.5	-44.1	172.1	179.9	64.3	0	0	0	111.4	F297 L364 F365 I366 F371 V372	F297-L368 HydrophobicContact CE1-CD1 3.89Å; F297-L368 HydrophobicContact CE2-CB 3.9Å; F297-L368 HydrophobicContact CZ-CB 3.75Å; F297-L368 HydrophobicContact CZ-CD1 3.9Å; F297-L368 HydrophobicContact CZ-CG 4.26Å; L364-L368 VanDerWaalsContact O-CB 3.25Å; L364-L368 WeakPolarHBondContact O-CB 3.37Å; L364-L368 PolarHBondContact O-N 3.49Å; F365-L368 WeakPolarHBondContact O-CB 3.42Å; F365-L368 PolarHBondContact O-N 3.41Å; I366-L368 VanDerWaalsContact C-N 3.34Å; I366-L368 PolarHBondContact O-N 2.92Å; L368-F371 PolarHBondContact O-N 3.16Å; L368-V372 HydrophobicContact CD1-CG2 4.21Å; L368-V372 HydrophobicContact CG-CG2 4.39Å; L368-V372 VanDerWaalsContact O-CG2 3.3Å; L368-V372 WeakPolarHBondContact O-CG2 3.25Å; L368-V372 PolarHBondContact O-N 3.18Å
369	C	90	Very high	83.3	Confident	27 Å²	27	50.7 Å²	50.7	18%	0.182	27%	0.267	C	S	.	.	H	α-helix	trans	-58.7	-48.6	174.5	-67.5	0	0	0	0	111.2	F365 I366 L367 F371 V372 F373 L400	F365-C369 PolarHBondContact O-N 3.36Å; F365-C369 PolarHBondContact O-SG 2.82Å; I366-C369 WeakPolarHBondContact O-CB 3.02Å; I366-C369 PolarHBondContact O-N 3.29Å; I366-C369 VanDerWaalsContact O-N 3.16Å; L367-C369 VanDerWaalsContact C-N 3.31Å; L367-C369 PolarHBondContact O-N 2.95Å; C369-F371 VanDerWaalsContact C-N 3.29Å; C369-F371 PolarHBondContact O-N 3.41Å; C369-V372 PolarHBondContact O-N 3.03Å; C369-F373 WeakPolarHBondContact O-CB 3.23Å; C369-F373 VanDerWaalsContact O-CD2 3.27Å; C369-F373 WeakPolarHBondContact O-CD2 3.35Å; C369-F373 PolarHBondContact O-N 3.32Å; C369-L400 HydrophobicContact CB-CD1 4.05Å; C369-L400 HydrophobicContact CB-CD2 4.04Å
370	L	86.5	Confident	82	Confident	6 Å²	6	51.1 Å²	51.1	3%	0.031	27%	0.268	C	S	.	.	H	α-helix	trans	-58.9	-40.1	177.4	-71.3	171.5	0	0	0	112.3	I366 L367 G374 F397 L400 Y404	I366-L370 HydrophobicContact CG2-CD1 4.3Å; I366-L370 PolarHBondContact O-N 3Å; L367-L370 WeakPolarHBondContact O-CB 3.46Å; L367-L370 PolarHBondContact O-N 2.87Å; L367-L370 VanDerWaalsContact O-N 3.16Å; L370-G374 PolarHBondContact O-N 3.16Å; L370-F397 HydrophobicContact CD2-CD2 4.4Å; L370-F397 HydrophobicContact CD2-CE2 4.22Å; L370-L400 HydrophobicContact CD2-CB 3.7Å; L370-L400 HydrophobicContact CG-CB 4.32Å; L370-Y404 HydrophobicContact CD1-CD2 4.36Å; L370-Y404 HydrophobicContact CD1-CG 4.35Å
371	F	84.1	Confident	80.6	Confident	3 Å²	3	52 Å²	52	1%	0.013	27%	0.274	C	S	.	.	H	α-helix	trans	-61.7	-55.1	173.5	-85.8	-72.4	0	0	0	111.7	Y289 L293 T296 F297 L367 L368 C369 F373 G374 S375 F383	Y289-F371 AromaticContact CE2-CD1 3.88Å; Y289-F371 HydrophobicContact CE2-CD1 3.88Å; Y289-F371 AromaticContact CZ-CD1 3.84Å; Y289-F371 WeakPolarHBondContact OH-CB 3.32Å; Y289-F371 PolarHBondContact OH-O 2.89Å; L293-F371 HydrophobicContact CB-CD1 3.85Å; L293-F371 HydrophobicContact CB-CE1 3.68Å; L293-F371 HydrophobicContact CB-CZ 4.4Å; L293-F371 HydrophobicContact CD1-CB 3.81Å; L293-F371 HydrophobicContact CD1-CD1 3.37Å; L293-F371 HydrophobicContact CD1-CD2 3.7Å; L293-F371 HydrophobicContact CD1-CE1 3.85Å; L293-F371 HydrophobicContact CD1-CE2 4.19Å; L293-F371 HydrophobicContact CD1-CG 3.34Å; L293-F371 HydrophobicContact CD1-CZ 4.28Å; L293-F371 HydrophobicContact CG-CD1 4.18Å; L293-F371 HydrophobicContact CG-CE1 4.39Å; T296-F371 WeakPolarHBondContact OG1-CZ 3.34Å; F297-F371 HydrophobicContact CB-CD2 3.98Å; F297-F371 HydrophobicContact CB-CE2 3.62Å; F297-F371 HydrophobicContact CB-CZ 4.36Å; F297-F371 HydrophobicContact CG-CD2 4.27Å; F297-F371 HydrophobicContact CG-CE2 4.37Å; L367-F371 HydrophobicContact CD1-CD2 4.04Å; L367-F371 HydrophobicContact CD1-CE2 3.64Å; L367-F371 HydrophobicContact CD2-CE2 4.3Å; L367-F371 HydrophobicContact CG-CD2 3.88Å; L367-F371 HydrophobicContact CG-CE2 3.64Å; L367-F371 WeakPolarHBondContact O-CD2 3.36Å; L367-F371 PolarHBondContact O-N 3.42Å; L368-F371 PolarHBondContact O-N 3.16Å; C369-F371 VanDerWaalsContact C-N 3.29Å; C369-F371 PolarHBondContact O-N 3.41Å; F371-F373 VanDerWaalsContact C-N 3.28Å; F371-F373 PolarHBondContact O-N 3.4Å; F371-G374 CarbonylContact O-C 3.55Å; F371-G374 PolarHBondContact O-N 3.29Å; F371-G374 VanDerWaalsContact O-N 3.07Å; F371-S375 PolarHBondContact O-N 3.32Å; F371-F383 HydrophobicContact CD1-CD1 4.14Å; F371-F383 AromaticContact CD1-CE1 3.11Å; F371-F383 HydrophobicContact CD1-CE1 3.11Å; F371-F383 AromaticContact CD1-CZ 3.44Å; F371-F383 HydrophobicContact CD1-CZ 3.44Å; F371-F383 VanDerWaalsContact CD1-CZ 3.44Å; F371-F383 HydrophobicContact CE1-CD1 4.13Å; F371-F383 AromaticContact CE1-CE1 3.17Å; F371-F383 HydrophobicContact CE1-CE1 3.17Å; F371-F383 AromaticContact CE1-CE2 3.94Å; F371-F383 HydrophobicContact CE1-CE2 3.94Å; F371-F383 AromaticContact CE1-CZ 3.05Å; F371-F383 HydrophobicContact CE1-CZ 3.05Å; F371-F383 AromaticContact CG-CE1 3.87Å; F371-F383 HydrophobicContact CG-CE1 3.87Å; F371-F383 AromaticContact CZ-CE1 3.92Å; F371-F383 HydrophobicContact CZ-CE1 3.92Å; F371-F383 HydrophobicContact CZ-CE2 4.47Å; F371-F383 AromaticContact CZ-CZ 3.9Å; F371-F383 HydrophobicContact CZ-CZ 3.9Å
372	V	86.6	Confident	78.9	Confident	67 Å²	67	48.6 Å²	48.6	41%	0.406	26%	0.258	S	S	.	.	H	α-helix	trans	-56.3	-43.3	179.7	172.2	0	0	0	0	111.2	L368 C369 S375 I376	L368-V372 HydrophobicContact CD1-CG2 4.21Å; L368-V372 HydrophobicContact CG-CG2 4.39Å; L368-V372 VanDerWaalsContact O-CG2 3.3Å; L368-V372 WeakPolarHBondContact O-CG2 3.25Å; L368-V372 PolarHBondContact O-N 3.18Å; C369-V372 PolarHBondContact O-N 3.03Å; V372-S375 PolarHBondContact O-N 3.5Å; V372-I376 HydrophobicContact CG1-CD1 3.63Å; V372-I376 HydrophobicContact CG1-CG1 4.41Å; V372-I376 VanDerWaalsContact O-CG1 3.29Å; V372-I376 WeakPolarHBondContact O-CG1 3.46Å; V372-I376 PolarHBondContact O-N 2.93Å
373	F	83.3	Confident	77	Confident	36 Å²	36	45.6 Å²	45.6	16%	0.158	24%	0.241	C	C	.	.	H	α-helix	trans	-60.2	-49.6	174.4	-92.2	-97.2	0	0	0	112.1	C369 F371 S375 I376 Y377 I393 L396 F397 L400	C369-F373 WeakPolarHBondContact O-CB 3.23Å; C369-F373 VanDerWaalsContact O-CD2 3.27Å; C369-F373 WeakPolarHBondContact O-CD2 3.35Å; C369-F373 PolarHBondContact O-N 3.32Å; F371-F373 VanDerWaalsContact C-N 3.28Å; F371-F373 PolarHBondContact O-N 3.4Å; F373-S375 PolarHBondContact O-N 2.84Å; F373-I376 PolarHBondContact O-N 3.39Å; F373-Y377 AromaticContact CD1-CD2 3.87Å; F373-Y377 HydrophobicContact CD1-CD2 3.87Å; F373-Y377 AromaticContact CD1-CE2 3.68Å; F373-Y377 HydrophobicContact CD1-CE2 3.68Å; F373-Y377 HydrophobicContact CE1-CD2 4.47Å; F373-Y377 AromaticContact CE1-CE2 3.83Å; F373-Y377 HydrophobicContact CE1-CE2 3.83Å; F373-Y377 WeakPolarHBondContact O-CD2 3.25Å; F373-Y377 PolarHBondContact O-N 3.33Å; F373-I393 HydrophobicContact CE1-CG2 4.41Å; F373-L396 HydrophobicContact CE1-CD2 3.87Å; F373-L396 HydrophobicContact CE1-CG 4.16Å; F373-L396 HydrophobicContact CE2-CD2 4.45Å; F373-L396 HydrophobicContact CZ-CD2 3.41Å; F373-L396 VanDerWaalsContact CZ-CD2 3.41Å; F373-L396 HydrophobicContact CZ-CG 3.88Å; F373-F397 HydrophobicContact CB-CD2 4.23Å; F373-L400 HydrophobicContact CD2-CD1 3.68Å; F373-L400 HydrophobicContact CE2-CD1 3.71Å; F373-L400 HydrophobicContact CG-CD1 4.25Å; F373-L400 HydrophobicContact CZ-CD1 4.3Å
374	G	76.4	Confident	75.4	Confident	14 Å²	14	45.5 Å²	45.5	14%	0.144	24%	0.242	C	C	.	.	H	α-helix	trans	-64.3	-22.1	177	0	0	0	0	0	114.2	L370 F371	L370-G374 PolarHBondContact O-N 3.16Å; F371-G374 CarbonylContact O-C 3.55Å; F371-G374 PolarHBondContact O-N 3.29Å; F371-G374 VanDerWaalsContact O-N 3.07Å
375	S	78	Confident	74	Confident	71 Å²	71	45.8 Å²	45.8	50%	0.497	24%	0.243	S	C	.	.	H	α-helix	trans	-82.7	-31.6	174.5	-173.5	0	0	0	0	113.6	Y289 F371 V372 F373	Y289-S375 WeakPolarHBondContact OH-CB 3.16Å; F371-S375 PolarHBondContact O-N 3.32Å; V372-S375 PolarHBondContact O-N 3.5Å; F373-S375 PolarHBondContact O-N 2.84Å
376	I	80.7	Confident	72.3	Confident	107 Å²	107	39.7 Å²	39.7	55%	0.549	22%	0.217	S	C	.	.	H	α-helix	trans	-82.6	-41.3	-177	-69.6	168.7	0	0	0	110.3	V372 F373	V372-I376 HydrophobicContact CG1-CD1 3.63Å; V372-I376 HydrophobicContact CG1-CG1 4.41Å; V372-I376 VanDerWaalsContact O-CG1 3.29Å; V372-I376 WeakPolarHBondContact O-CG1 3.46Å; V372-I376 PolarHBondContact O-N 2.93Å; F373-I376 PolarHBondContact O-N 3.39Å
377	Y	73.6	Confident	70.9	Confident	80 Å²	80	44.9 Å²	44.9	31%	0.314	24%	0.239	S	C	.	.			trans	-106.5	107.2	-170.9	-62.8	-73.8	0	0	0	110.9	F373 D379 Y380 I393	F373-Y377 AromaticContact CD1-CD2 3.87Å; F373-Y377 HydrophobicContact CD1-CD2 3.87Å; F373-Y377 AromaticContact CD1-CE2 3.68Å; F373-Y377 HydrophobicContact CD1-CE2 3.68Å; F373-Y377 HydrophobicContact CE1-CD2 4.47Å; F373-Y377 AromaticContact CE1-CE2 3.83Å; F373-Y377 HydrophobicContact CE1-CE2 3.83Å; F373-Y377 WeakPolarHBondContact O-CD2 3.25Å; F373-Y377 PolarHBondContact O-N 3.33Å; Y377-D379 PolarHBondContact O-N 2.87Å; Y377-D379 VanDerWaalsContact O-N 3.16Å; Y377-Y380 VanDerWaalsContact CB-CE2 3.47Å; Y377-Y380 HydrophobicContact CD2-CE2 4.37Å; Y377-Y380 HydrophobicContact CG-CD2 4.2Å; Y377-Y380 AromaticContact CG-CE2 3.93Å; Y377-Y380 HydrophobicContact CG-CE2 3.93Å; Y377-Y380 PolarHBondContact O-N 3.28Å; Y377-I393 HydrophobicContact CD1-CD1 4.48Å; Y377-I393 HydrophobicContact CD1-CG2 4.25Å; Y377-I393 HydrophobicContact CD2-CG2 4.03Å; Y377-I393 HydrophobicContact CE1-CD1 3.65Å; Y377-I393 HydrophobicContact CE1-CG1 4.38Å; Y377-I393 HydrophobicContact CE1-CG2 3.98Å; Y377-I393 HydrophobicContact CE2-CG2 3.74Å; Y377-I393 HydrophobicContact CG-CG2 4.27Å
378	D	62	Low	69.6	Low	84 Å²	84	50.9 Å²	50.9	45%	0.449	26%	0.264	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62.5	-22.3	-176.9	-76.8	-21	0	0	0	113.8	P282 K284 Y380	P282-D378 WeakPolarHBondContact CB-O 3.42Å; P282-D378 VanDerWaalsContact CG-O 3.24Å; P282-D378 WeakPolarHBondContact CG-O 3.24Å; K284-D378 WeakPolarHBondContact CE-OD1 3.41Å; K284-D378 IonicContact NZ-OD1 2.68Å; K284-D378 PolarHBondContact NZ-OD1 3.31Å; K284-D378 IonicContact NZ-OD2 2.76Å; K284-D378 PolarHBondContact NZ-OD2 3.49Å; D378-Y380 VanDerWaalsContact C-N 3.28Å; D378-Y380 PolarHBondContact O-N 3.47Å
379	D	60.3	Low	68	Low	111 Å²	111	47.6 Å²	47.6	59%	0.594	25%	0.247	S	C	*	.	T	Hydrogen-bonded Turn	trans	-72.4	-19.3	-178.8	-68.1	-38.6	0	0	0	113.7	Y377 C381	Y377-D379 PolarHBondContact O-N 2.87Å; Y377-D379 VanDerWaalsContact O-N 3.16Å; D379-C381 PolarHBondContact O-N 3.24Å
380	Y	61.5	Low	66.7	Low	18 Å²	18	48 Å²	48	7%	0.071	25%	0.249	C	C	.	.			trans	-93.4	84.6	-179.1	-57.3	-89.5	0	0	0	109.7	Y377 D378 C382 I385 A386 I393 D394 F397	Y377-Y380 VanDerWaalsContact CB-CE2 3.47Å; Y377-Y380 HydrophobicContact CD2-CE2 4.37Å; Y377-Y380 HydrophobicContact CG-CD2 4.2Å; Y377-Y380 AromaticContact CG-CE2 3.93Å; Y377-Y380 HydrophobicContact CG-CE2 3.93Å; Y377-Y380 PolarHBondContact O-N 3.28Å; D378-Y380 VanDerWaalsContact C-N 3.28Å; D378-Y380 PolarHBondContact O-N 3.47Å; Y380-C382 PolarHBondContact O-N 3.43Å; Y380-I385 VanDerWaalsContact CD1-O 3.26Å; Y380-I385 WeakPolarHBondContact CD1-O 3.44Å; Y380-A386 HydrophobicContact CE1-CB 3.98Å; Y380-I393 HydrophobicContact CE2-CG2 4.08Å; Y380-I393 WeakPolarHBondContact OH-CG2 3.49Å; Y380-D394 WeakPolarHBondContact CE1-OD1 3.3Å; Y380-D394 PolarHBondContact OH-N 2.91Å; Y380-D394 PolarHBondContact OH-OD1 2.83Å; Y380-F397 AromaticContact CD1-CD1 3.88Å; Y380-F397 HydrophobicContact CD1-CD1 3.88Å; Y380-F397 HydrophobicContact CD1-CD2 4.22Å; Y380-F397 AromaticContact CD1-CE1 3.85Å; Y380-F397 HydrophobicContact CD1-CE1 3.85Å; Y380-F397 HydrophobicContact CD1-CE2 4.19Å; Y380-F397 HydrophobicContact CD1-CG 4.02Å; Y380-F397 AromaticContact CD1-CZ 3.95Å; Y380-F397 HydrophobicContact CD1-CZ 3.95Å; Y380-F397 HydrophobicContact CE1-CB 4.21Å; Y380-F397 AromaticContact CE1-CD1 3.98Å; Y380-F397 HydrophobicContact CE1-CD1 3.98Å; Y380-F397 HydrophobicContact CE1-CE1 4.41Å; Y380-F397 AromaticContact CE1-CG 3.99Å; Y380-F397 HydrophobicContact CE1-CG 3.99Å; Y380-F397 HydrophobicContact CG-CE2 4.41Å; Y380-F397 HydrophobicContact CG-CZ 4.43Å
381	C	54.6	Low	66.2	Low	22 Å²	22	53.8 Å²	53.8	15%	0.149	28%	0.276	C	S	.	.			trans	-68.6	128.2	171	-172.3	0	0	0	0	109.8	P282 F283 D379 I385	P282-C381 HydrophobicContact CB-CB 4.09Å; F283-C381 PolarHBondContact N-SG 2.94Å; F283-C381 VanDerWaalsContact N-SG 3.42Å; D379-C381 PolarHBondContact O-N 3.24Å; C381-I385 WeakPolarHBondContact O-CB 3.47Å; C381-I385 VanDerWaalsContact O-CD1 3.25Å; C381-I385 WeakPolarHBondContact O-CD1 3.34Å; C381-I385 VanDerWaalsContact O-CG1 3.24Å; C381-I385 WeakPolarHBondContact O-CG1 3.42Å
382	C	54.1	Low	66.1	Low	22 Å²	22	59.3 Å²	59.3	15%	0.149	30%	0.297	C	S	.	.	T	Hydrogen-bonded Turn	trans	53.7	66.4	170.7	-54.5	0	0	0	0	113.8	F215 L271 Y380 L384	F215-C382 HydrophobicContact CE2-CB 3.66Å; F215-C382 VanDerWaalsContact CE2-O 3.23Å; F215-C382 WeakPolarHBondContact CE2-O 3.21Å; F215-C382 HydrophobicContact CZ-CB 3.6Å; F215-C382 WeakPolarHBondContact CZ-O 3.4Å; L271-C382 HydrophobicContact CD2-CB 4.48Å; Y380-C382 PolarHBondContact O-N 3.43Å; C382-L384 PolarHBondContact O-N 3.16Å
383	F	52.4	Low	66	Low	24 Å²	24	59 Å²	59	11%	0.105	29%	0.292	C	S	.	.	T	Hydrogen-bonded Turn	trans	54.1	-10	158.7	-55.3	-71.8	0	0	0	120.6	F215 Y289 K292 F371 F397	F215-F383 HydrophobicContact CE1-CB 4.38Å; F215-F383 AromaticContact CE1-CD2 3.83Å; F215-F383 HydrophobicContact CE1-CD2 3.83Å; F215-F383 HydrophobicContact CZ-CB 4.02Å; F215-F383 AromaticContact CZ-CD2 3.92Å; F215-F383 HydrophobicContact CZ-CD2 3.92Å; F215-F383 HydrophobicContact CZ-CG 4.48Å; Y289-F383 HydrophobicContact CD2-CE1 4.03Å; Y289-F383 AromaticContact CD2-CZ 3.56Å; Y289-F383 HydrophobicContact CD2-CZ 3.56Å; Y289-F383 AromaticContact CE2-CE1 3.58Å; Y289-F383 HydrophobicContact CE2-CE1 3.58Å; Y289-F383 AromaticContact CE2-CZ 3.58Å; Y289-F383 HydrophobicContact CE2-CZ 3.58Å; K292-F383 HydrophobicContact CB-CE2 4.12Å; K292-F383 HydrophobicContact CD-CD2 4.43Å; K292-F383 HydrophobicContact CD-CE2 3.85Å; F371-F383 HydrophobicContact CD1-CD1 4.14Å; F371-F383 AromaticContact CD1-CE1 3.11Å; F371-F383 HydrophobicContact CD1-CE1 3.11Å; F371-F383 AromaticContact CD1-CZ 3.44Å; F371-F383 HydrophobicContact CD1-CZ 3.44Å; F371-F383 VanDerWaalsContact CD1-CZ 3.44Å; F371-F383 HydrophobicContact CE1-CD1 4.13Å; F371-F383 AromaticContact CE1-CE1 3.17Å; F371-F383 HydrophobicContact CE1-CE1 3.17Å; F371-F383 AromaticContact CE1-CE2 3.94Å; F371-F383 HydrophobicContact CE1-CE2 3.94Å; F371-F383 AromaticContact CE1-CZ 3.05Å; F371-F383 HydrophobicContact CE1-CZ 3.05Å; F371-F383 AromaticContact CG-CE1 3.87Å; F371-F383 HydrophobicContact CG-CE1 3.87Å; F371-F383 AromaticContact CZ-CE1 3.92Å; F371-F383 HydrophobicContact CZ-CE1 3.92Å; F371-F383 HydrophobicContact CZ-CE2 4.47Å; F371-F383 AromaticContact CZ-CZ 3.9Å; F371-F383 HydrophobicContact CZ-CZ 3.9Å; F383-F397 WeakPolarHBondContact O-CZ 3.24Å
384	L	53.9	Low	65.8	Low	14 Å²	14	57.8 Å²	57.8	7%	0.073	29%	0.288	C	S	.	.	S	Bend	trans	-143.6	5.7	-168.8	-68.7	172.8	0	0	0	113.7	D184 R187 S214 F215 C382	D184-L384 WeakPolarHBondContact OD2-CD2 3.25Å; R187-L384 PolarHBondContact NH1-O 2.99Å; R187-L384 PolarHBondContact NH2-O 2.94Å; S214-L384 VanDerWaalsContact OG-CD1 3.27Å; S214-L384 WeakPolarHBondContact OG-CD1 3.4Å; F215-L384 HydrophobicContact CE2-CD1 4.28Å; F215-L384 HydrophobicContact CZ-CD1 4.46Å; C382-L384 PolarHBondContact O-N 3.16Å
385	I	57.9	Low	66.2	Low	25 Å²	25	57.4 Å²	57.4	13%	0.128	28%	0.282	C	S	.	.			trans	-110.7	88.5	-169.7	-54.8	-177.1	0	0	0	110.1	R199 I211 Y380 C381	R199-I385 VanDerWaalsContact NH1-CD1 3.31Å; I211-I385 HydrophobicContact CD1-CD1 4.01Å; Y380-I385 VanDerWaalsContact CD1-O 3.26Å; Y380-I385 WeakPolarHBondContact CD1-O 3.44Å; C381-I385 WeakPolarHBondContact O-CB 3.47Å; C381-I385 VanDerWaalsContact O-CD1 3.25Å; C381-I385 WeakPolarHBondContact O-CD1 3.34Å; C381-I385 VanDerWaalsContact O-CG1 3.24Å; C381-I385 WeakPolarHBondContact O-CG1 3.42Å
386	A	56.6	Low	66.7	Low	0 Å²	0	57.6 Å²	57.6	0%	0	28%	0.277	C	S	.	.			trans	-76.8	125.6	157.3	0	0	0	0	0	108.7	L191 Y380 D394 F397	L191-A386 HydrophobicContact CD2-CB 4.21Å; Y380-A386 HydrophobicContact CE1-CB 3.98Å; A386-D394 HydrophobicContact CB-CB 4.28Å; A386-F397 HydrophobicContact CB-CD1 4.36Å
387	K	58.9	Low	67	Low	124 Å²	124	52.5 Å²	52.5	54%	0.539	25%	0.251	S	S	.	.	S	Bend	trans	-72.2	-35.7	-177	-170.4	172.2	-177.1	171.6	0	111.8
388	K	60.3	Low	67.6	Low	141 Å²	141	48.7 Å²	48.7	61%	0.613	24%	0.236	S	C	*	.			trans	-152.6	141.1	176.6	-65.3	-176.1	179.3	174.8	0	107.8	C390 D394	K388-C390 PolarHBondContact O-N 3.1Å; K388-C390 VanDerWaalsContact O-N 3.12Å; K388-D394 WeakPolarHBondContact O-CB 3.47Å
389	N	56.6	Low	69	Low	4 Å²	4	47 Å²	47	2%	0.021	23%	0.227	C	C	.	.	T	Hydrogen-bonded Turn	trans	-88	45.7	178.7	-162.4	30	0	0	0	112.2	Q24 L191 I395 N398	Q24-N389 WeakPolarHBondContact CG-ND2 3.49Å; Q24-N389 PolarHBondContact NE2-ND2 3.39Å; L191-N389 HydrophobicContact CD1-CB 4.13Å; L191-N389 HydrophobicContact CG-CB 4.25Å; N389-I395 WeakPolarHBondContact OD1-CG1 3.34Å; N389-I395 PolarHBondContact OD1-N 3.2Å; N389-N398 VanDerWaalsContact CG-ND2 3.34Å; N389-N398 PolarHBondContact OD1-ND2 3.39Å
390	C	62	Low	70.5	Confident	34 Å²	34	42.7 Å²	42.7	23%	0.23	20%	0.204	C	C	.	.	T	Hydrogen-bonded Turn	trans	-100.8	-19.2	-171.9	-54.7	0	0	0	0	113.1	C2 K388	C2-C390 HydrophobicContact CB-CB 3.87Å; C2-C390 WeakPolarHBondContact CB-SG 3.25Å; C2-C390 WeakPolarHBondContact SG-CB 3.35Å; C2-C390 CovalentContact SG-SG 2.03Å; C2-C390 PolarHBondContact SG-SG 3.41Å; K388-C390 PolarHBondContact O-N 3.1Å; K388-C390 VanDerWaalsContact O-N 3.12Å
391	H	77.2	Confident	71.8	Confident	129 Å²	129	41.9 Å²	41.9	60%	0.597	20%	0.2	S	C	*	.	S	Bend	trans	-108	154.1	178.5	-65.1	-72.1	0	0	0	112	I393 D394 I395	H391-I393 PolarHBondContact O-N 3Å; H391-I393 VanDerWaalsContact O-N 3.12Å; H391-D394 WeakPolarHBondContact CB-OD2 3.31Å; H391-D394 IonicContact CD2-OD2 3.97Å; H391-D394 PolarHBondContact N-OD2 3.29Å; H391-D394 VanDerWaalsContact N-OD2 3.13Å; H391-D394 WeakPolarHBondContact O-CB 3.44Å; H391-D394 PolarHBondContact O-N 3.07Å; H391-I395 PolarHBondContact O-N 3.1Å
392	W	82	Confident	73.6	Confident	118 Å²	118	40.8 Å²	40.8	45%	0.447	19%	0.193	S	C	.	.	H	α-helix	trans	-53.7	-31.8	175.4	-79.2	114.2	0	0	0	113.3	L19 Q20 I23 I395 L396	L19-W392 HydrophobicContact CD2-CH2 4.45Å; Q20-W392 HydrophobicContact CG-CD2 4Å; Q20-W392 VanDerWaalsContact CG-CE2 3.48Å; Q20-W392 HydrophobicContact CG-CE3 4.35Å; Q20-W392 HydrophobicContact CG-CH2 3.81Å; Q20-W392 HydrophobicContact CG-CZ2 3.37Å; Q20-W392 HydrophobicContact CG-CZ3 4.27Å; Q20-W392 VanDerWaalsContact NE2-CE2 3.34Å; I23-W392 HydrophobicContact CD1-CH2 3.51Å; I23-W392 HydrophobicContact CD1-CZ3 3.61Å; W392-I395 HydrophobicContact CE3-CD1 4.33Å; W392-I395 PolarHBondContact O-N 3.07Å; W392-L396 WeakPolarHBondContact O-CB 3.47Å; W392-L396 PolarHBondContact O-N 2.89Å
393	I	83.2	Confident	75.4	Confident	60 Å²	60	42.2 Å²	42.2	31%	0.308	20%	0.199	S	C	.	.	H	α-helix	trans	-67.4	-41.1	178.5	-59.5	161.8	0	0	0	110.4	F373 Y377 Y380 H391 L396 F397	F373-I393 HydrophobicContact CE1-CG2 4.41Å; Y377-I393 HydrophobicContact CD1-CD1 4.48Å; Y377-I393 HydrophobicContact CD1-CG2 4.25Å; Y377-I393 HydrophobicContact CD2-CG2 4.03Å; Y377-I393 HydrophobicContact CE1-CD1 3.65Å; Y377-I393 HydrophobicContact CE1-CG1 4.38Å; Y377-I393 HydrophobicContact CE1-CG2 3.98Å; Y377-I393 HydrophobicContact CE2-CG2 3.74Å; Y377-I393 HydrophobicContact CG-CG2 4.27Å; Y380-I393 HydrophobicContact CE2-CG2 4.08Å; Y380-I393 WeakPolarHBondContact OH-CG2 3.49Å; H391-I393 PolarHBondContact O-N 3Å; H391-I393 VanDerWaalsContact O-N 3.12Å; I393-L396 PolarHBondContact O-N 2.91Å; I393-F397 WeakPolarHBondContact O-CB 3.48Å; I393-F397 PolarHBondContact O-N 3.37Å
394	D	80.1	Confident	77.3	Confident	12 Å²	12	41.6 Å²	41.6	6%	0.064	20%	0.196	C	C	.	.	H	α-helix	trans	-64.3	-42.4	175.5	-58.1	-57.6	0	0	0	111.4	Y380 A386 K388 H391 L396 F397 N398	Y380-D394 WeakPolarHBondContact CE1-OD1 3.3Å; Y380-D394 PolarHBondContact OH-N 2.91Å; Y380-D394 PolarHBondContact OH-OD1 2.83Å; A386-D394 HydrophobicContact CB-CB 4.28Å; K388-D394 WeakPolarHBondContact O-CB 3.47Å; H391-D394 WeakPolarHBondContact CB-OD2 3.31Å; H391-D394 IonicContact CD2-OD2 3.97Å; H391-D394 PolarHBondContact N-OD2 3.29Å; H391-D394 VanDerWaalsContact N-OD2 3.13Å; H391-D394 WeakPolarHBondContact O-CB 3.44Å; H391-D394 PolarHBondContact O-N 3.07Å; D394-L396 VanDerWaalsContact C-N 3.33Å; D394-L396 PolarHBondContact O-N 2.64Å; D394-F397 PolarHBondContact O-N 3.5Å; D394-N398 WeakPolarHBondContact O-CB 3.39Å; D394-N398 PolarHBondContact O-N 2.83Å; D394-N398 PolarHBondContact O-ND2 2.96Å; D394-N398 VanDerWaalsContact O-ND2 3.15Å
395	I	84.2	Confident	79.2	Confident	6 Å²	6	41 Å²	41	3%	0.031	19%	0.193	C	C	.	.	H	α-helix	trans	-60.8	-45.9	177.4	-64.4	175.5	0	0	0	110	Q20 I23 I27 N389 H391 W392 N398 L399	Q20-I395 HydrophobicContact CB-CD1 4.07Å; Q20-I395 HydrophobicContact CG-CD1 4.22Å; I23-I395 HydrophobicContact CG2-CG2 3.95Å; I27-I395 HydrophobicContact CD1-CG2 3.39Å; N389-I395 WeakPolarHBondContact OD1-CG1 3.34Å; N389-I395 PolarHBondContact OD1-N 3.2Å; H391-I395 PolarHBondContact O-N 3.1Å; W392-I395 HydrophobicContact CE3-CD1 4.33Å; W392-I395 PolarHBondContact O-N 3.07Å; I395-N398 PolarHBondContact O-N 3.26Å; I395-L399 WeakPolarHBondContact O-CB 3.42Å; I395-L399 PolarHBondContact O-N 3.04Å
396	L	88.8	Confident	80.9	Confident	75 Å²	75	43.5 Å²	43.5	39%	0.393	20%	0.203	S	C	.	.	H	α-helix	trans	-65.2	-41.8	178.8	-179	55.7	0	0	0	112	F373 W392 I393 D394 L399 L400	F373-L396 HydrophobicContact CE1-CD2 3.87Å; F373-L396 HydrophobicContact CE1-CG 4.16Å; F373-L396 HydrophobicContact CE2-CD2 4.45Å; F373-L396 HydrophobicContact CZ-CD2 3.41Å; F373-L396 VanDerWaalsContact CZ-CD2 3.41Å; F373-L396 HydrophobicContact CZ-CG 3.88Å; W392-L396 WeakPolarHBondContact O-CB 3.47Å; W392-L396 PolarHBondContact O-N 2.89Å; I393-L396 PolarHBondContact O-N 2.91Å; D394-L396 VanDerWaalsContact C-N 3.33Å; D394-L396 PolarHBondContact O-N 2.64Å; L396-L399 HydrophobicContact CD1-CD2 4.47Å; L396-L399 WeakPolarHBondContact O-CB 3.24Å; L396-L399 PolarHBondContact O-N 3.26Å; L396-L400 WeakPolarHBondContact O-CG 3.47Å; L396-L400 PolarHBondContact O-N 2.92Å
397	F	86.5	Confident	82.5	Confident	0 Å²	0	44.2 Å²	44.2	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-64.1	-42.6	176.4	-178.8	-97.2	0	0	0	112.4	L370 F373 Y380 F383 A386 I393 D394 L399 L400 S401	L370-F397 HydrophobicContact CD2-CD2 4.4Å; L370-F397 HydrophobicContact CD2-CE2 4.22Å; F373-F397 HydrophobicContact CB-CD2 4.23Å; Y380-F397 AromaticContact CD1-CD1 3.88Å; Y380-F397 HydrophobicContact CD1-CD1 3.88Å; Y380-F397 HydrophobicContact CD1-CD2 4.22Å; Y380-F397 AromaticContact CD1-CE1 3.85Å; Y380-F397 HydrophobicContact CD1-CE1 3.85Å; Y380-F397 HydrophobicContact CD1-CE2 4.19Å; Y380-F397 HydrophobicContact CD1-CG 4.02Å; Y380-F397 AromaticContact CD1-CZ 3.95Å; Y380-F397 HydrophobicContact CD1-CZ 3.95Å; Y380-F397 HydrophobicContact CE1-CB 4.21Å; Y380-F397 AromaticContact CE1-CD1 3.98Å; Y380-F397 HydrophobicContact CE1-CD1 3.98Å; Y380-F397 HydrophobicContact CE1-CE1 4.41Å; Y380-F397 AromaticContact CE1-CG 3.99Å; Y380-F397 HydrophobicContact CE1-CG 3.99Å; Y380-F397 HydrophobicContact CG-CE2 4.41Å; Y380-F397 HydrophobicContact CG-CZ 4.43Å; F383-F397 WeakPolarHBondContact O-CZ 3.24Å; A386-F397 HydrophobicContact CB-CD1 4.36Å; I393-F397 WeakPolarHBondContact O-CB 3.48Å; I393-F397 PolarHBondContact O-N 3.37Å; D394-F397 PolarHBondContact O-N 3.5Å; F397-L399 VanDerWaalsContact C-N 3.33Å; F397-L399 PolarHBondContact O-N 2.96Å; F397-L400 PolarHBondContact O-N 3.32Å; F397-S401 WeakPolarHBondContact O-CB 3.05Å; F397-S401 PolarHBondContact O-N 3.36Å; F397-S401 PolarHBondContact O-OG 3.48Å
398	N	86.9	Confident	84.1	Confident	0 Å²	0	38.6 Å²	38.6	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-62.9	-40.8	174.5	-73.6	-29.8	0	0	0	111.4	N389 D394 I395 S401 I402	N389-N398 VanDerWaalsContact CG-ND2 3.34Å; N389-N398 PolarHBondContact OD1-ND2 3.39Å; D394-N398 WeakPolarHBondContact O-CB 3.39Å; D394-N398 PolarHBondContact O-N 2.83Å; D394-N398 PolarHBondContact O-ND2 2.96Å; D394-N398 VanDerWaalsContact O-ND2 3.15Å; I395-N398 PolarHBondContact O-N 3.26Å; N398-S401 PolarHBondContact O-N 3.38Å; N398-I402 WeakPolarHBondContact O-CB 3.49Å; N398-I402 WeakPolarHBondContact O-CG1 3.1Å; N398-I402 PolarHBondContact O-N 2.94Å
399	L	90.6	Very high	85.6	Confident	49 Å²	49	32.2 Å²	32.2	26%	0.257	16%	0.155	S	C	.	.	H	α-helix	trans	-60.2	-49.2	173.7	173.3	64.2	0	0	0	111.3	I27 I395 L396 F397 S401 I402 L403	I27-L399 HydrophobicContact CD1-CB 3.99Å; I27-L399 HydrophobicContact CG1-CB 4.29Å; I27-L399 HydrophobicContact CG1-CD1 4.1Å; I27-L399 HydrophobicContact CG2-CB 4.5Å; I395-L399 WeakPolarHBondContact O-CB 3.42Å; I395-L399 PolarHBondContact O-N 3.04Å; L396-L399 HydrophobicContact CD1-CD2 4.47Å; L396-L399 WeakPolarHBondContact O-CB 3.24Å; L396-L399 PolarHBondContact O-N 3.26Å; F397-L399 VanDerWaalsContact C-N 3.33Å; F397-L399 PolarHBondContact O-N 2.96Å; L399-S401 VanDerWaalsContact C-N 3.29Å; L399-S401 PolarHBondContact O-N 3.16Å; L399-I402 PolarHBondContact O-N 3.39Å; L399-L403 HydrophobicContact CD1-CD1 3.92Å; L399-L403 HydrophobicContact CD1-CD2 4.48Å; L399-L403 HydrophobicContact CD1-CG 3.93Å; L399-L403 HydrophobicContact CG-CD1 3.87Å; L399-L403 HydrophobicContact CG-CG 4.31Å; L399-L403 WeakPolarHBondContact O-CB 3.37Å; L399-L403 VanDerWaalsContact O-CG 3.24Å; L399-L403 WeakPolarHBondContact O-CG 3.26Å; L399-L403 PolarHBondContact O-N 3.26Å
400	L	91.6	Very high	87.3	Confident	20 Å²	20	35.2 Å²	35.2	11%	0.105	17%	0.171	C	C	.	.	H	α-helix	trans	-59.2	-41.2	177.9	-72.3	172.4	0	0	0	111.9	C369 L370 F373 L396 F397 L403 Y404	C369-L400 HydrophobicContact CB-CD1 4.05Å; C369-L400 HydrophobicContact CB-CD2 4.04Å; L370-L400 HydrophobicContact CD2-CB 3.7Å; L370-L400 HydrophobicContact CG-CB 4.32Å; F373-L400 HydrophobicContact CD2-CD1 3.68Å; F373-L400 HydrophobicContact CE2-CD1 3.71Å; F373-L400 HydrophobicContact CG-CD1 4.25Å; F373-L400 HydrophobicContact CZ-CD1 4.3Å; L396-L400 WeakPolarHBondContact O-CG 3.47Å; L396-L400 PolarHBondContact O-N 2.92Å; F397-L400 PolarHBondContact O-N 3.32Å; L400-L403 PolarHBondContact O-N 3.22Å; L400-Y404 PolarHBondContact O-N 3.07Å
401	S	89.5	Confident	88.6	Confident	0 Å²	0	33.9 Å²	33.9	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-66.5	-41.2	178.1	-56.2	0	0	0	0	111.9	F397 N398 L399 Y404 W405	F397-S401 WeakPolarHBondContact O-CB 3.05Å; F397-S401 PolarHBondContact O-N 3.36Å; F397-S401 PolarHBondContact O-OG 3.48Å; N398-S401 PolarHBondContact O-N 3.38Å; L399-S401 VanDerWaalsContact C-N 3.29Å; L399-S401 PolarHBondContact O-N 3.16Å; S401-Y404 WeakPolarHBondContact O-CB 3.27Å; S401-Y404 PolarHBondContact O-N 2.96Å; S401-W405 PolarHBondContact O-N 2.73Å
402	I	92	Very high	89.2	Confident	0 Å²	0	27.7 Å²	27.7	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-67.7	-39.6	174.6	-74.6	163.5	0	0	0	111.2	I27 I30 L185 L188 N398 L399 Y404 W405 F406	I27-I402 HydrophobicContact CG2-CD1 3.36Å; I30-I402 HydrophobicContact CB-CG2 4.31Å; I30-I402 HydrophobicContact CG2-CG2 3.82Å; L185-I402 HydrophobicContact CD1-CG1 3.98Å; L188-I402 HydrophobicContact CB-CD1 4.28Å; L188-I402 HydrophobicContact CB-CG1 4.08Å; L188-I402 HydrophobicContact CD1-CG1 4.3Å; N398-I402 WeakPolarHBondContact O-CB 3.49Å; N398-I402 WeakPolarHBondContact O-CG1 3.1Å; N398-I402 PolarHBondContact O-N 2.94Å; L399-I402 PolarHBondContact O-N 3.39Å; I402-Y404 VanDerWaalsContact C-N 3.29Å; I402-Y404 PolarHBondContact O-N 2.94Å; I402-W405 PolarHBondContact O-N 2.85Å; I402-F406 WeakPolarHBondContact O-CB 3.37Å; I402-F406 PolarHBondContact O-N 3.27Å
403	L	93	Very high	89.6	Confident	51 Å²	51	24.9 Å²	24.9	27%	0.267	12%	0.123	S	C	.	.	H	α-helix	trans	-64.7	-34.4	176.4	-72	172.4	0	0	0	112	I366 L399 L400 F406 I407	I366-L403 HydrophobicContact CD1-CB 3.49Å; I366-L403 VanDerWaalsContact CD1-CB 3.49Å; L399-L403 HydrophobicContact CD1-CD1 3.92Å; L399-L403 HydrophobicContact CD1-CD2 4.48Å; L399-L403 HydrophobicContact CD1-CG 3.93Å; L399-L403 HydrophobicContact CG-CD1 3.87Å; L399-L403 HydrophobicContact CG-CG 4.31Å; L399-L403 WeakPolarHBondContact O-CB 3.37Å; L399-L403 VanDerWaalsContact O-CG 3.24Å; L399-L403 WeakPolarHBondContact O-CG 3.26Å; L399-L403 PolarHBondContact O-N 3.26Å; L400-L403 PolarHBondContact O-N 3.22Å; L403-F406 PolarHBondContact O-N 3.21Å; L403-I407 WeakPolarHBondContact O-CG1 3.49Å; L403-I407 PolarHBondContact O-N 2.75Å
404	Y	92	Very high	89.8	Confident	12 Å²	12	22.8 Å²	22.8	5%	0.047	11%	0.113	C	C	.	.	H	α-helix	trans	-56.2	-51.7	171.2	169.2	-92.4	0	0	0	111.2	Y363 L367 L370 L400 S401 I402 F406 I407 L408	Y363-Y404 HydrophobicContact CD2-CD2 4.38Å; Y363-Y404 HydrophobicContact CD2-CE2 4.08Å; Y363-Y404 AromaticContact CE2-CD2 3.92Å; Y363-Y404 HydrophobicContact CE2-CD2 3.92Å; Y363-Y404 AromaticContact CE2-CE2 3.2Å; Y363-Y404 HydrophobicContact CE2-CE2 3.2Å; Y363-Y404 AromaticContact CE2-CZ 3.84Å; Y363-Y404 AromaticContact CZ-CE2 3.67Å; Y363-Y404 PolarHBondContact OH-OH 2.88Å; L367-Y404 HydrophobicContact CD1-CE2 4.35Å; L370-Y404 HydrophobicContact CD1-CD2 4.36Å; L370-Y404 HydrophobicContact CD1-CG 4.35Å; L400-Y404 PolarHBondContact O-N 3.07Å; S401-Y404 WeakPolarHBondContact O-CB 3.27Å; S401-Y404 PolarHBondContact O-N 2.96Å; I402-Y404 VanDerWaalsContact C-N 3.29Å; I402-Y404 PolarHBondContact O-N 2.94Å; Y404-F406 VanDerWaalsContact C-N 3.3Å; Y404-F406 PolarHBondContact O-N 3.31Å; Y404-I407 PolarHBondContact O-N 3.27Å; Y404-L408 HydrophobicContact CD1-CD1 4.12Å; Y404-L408 HydrophobicContact CE1-CD1 3.48Å; Y404-L408 VanDerWaalsContact CE1-CD1 3.48Å; Y404-L408 HydrophobicContact CE1-CG 4.46Å; Y404-L408 PolarHBondContact O-N 2.88Å; Y404-L408 VanDerWaalsContact O-N 3.14Å
405	W	92.8	Very high	90	Very high	0 Å²	0	22.6 Å²	22.6	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-61.9	-37.7	176.3	-74.6	107.3	0	0	0	112.6	H38 G180 D184 L185 S401 I402 L408 T409	H38-W405 AromaticContact NE2-CE3 3.91Å; H38-W405 PolarHBondContact NE2-O 3.34Å; G180-W405 VanDerWaalsContact C-CH2 3.47Å; D184-W405 HydrophobicContact CB-CZ2 3.84Å; D184-W405 PolarHBondContact OD2-NE1 2.97Å; L185-W405 HydrophobicContact CB-CD2 4.35Å; L185-W405 HydrophobicContact CB-CG 4.13Å; L185-W405 HydrophobicContact CD1-CB 4.07Å; L185-W405 HydrophobicContact CD1-CG 4.16Å; L185-W405 HydrophobicContact CD2-CB 4.17Å; L185-W405 HydrophobicContact CD2-CG 4.47Å; L185-W405 HydrophobicContact CG-CG 4.48Å; S401-W405 PolarHBondContact O-N 2.73Å; I402-W405 PolarHBondContact O-N 2.85Å; W405-L408 HydrophobicContact CE3-CD1 3.98Å; W405-L408 HydrophobicContact CZ3-CD1 4.09Å; W405-L408 WeakPolarHBondContact O-CB 3.47Å; W405-L408 PolarHBondContact O-N 3.28Å; W405-T409 PolarHBondContact O-N 3.25Å; W405-T409 PolarHBondContact O-OG1 2.86Å; W405-T409 VanDerWaalsContact O-OG1 3.06Å
406	F	93.3	Very high	90	Very high	78 Å²	78	23.2 Å²	23.2	34%	0.342	11%	0.114	S	C	.	.	H	α-helix	trans	-65.4	-40.8	177.6	-172.9	-109.6	0	0	0	112.6	S34 I402 L403 Y404 L408 T409 I410	S34-F406 WeakPolarHBondContact OG-CA 3.29Å; S34-F406 PolarHBondContact OG-N 3.28Å; I402-F406 WeakPolarHBondContact O-CB 3.37Å; I402-F406 PolarHBondContact O-N 3.27Å; L403-F406 PolarHBondContact O-N 3.21Å; Y404-F406 VanDerWaalsContact C-N 3.3Å; Y404-F406 PolarHBondContact O-N 3.31Å; F406-L408 VanDerWaalsContact C-N 3.35Å; F406-T409 VanDerWaalsContact O-CB 3.28Å; F406-T409 WeakPolarHBondContact O-CB 3.35Å; F406-T409 PolarHBondContact O-N 2.8Å; F406-I410 HydrophobicContact CD1-CD1 3.75Å; F406-I410 HydrophobicContact CD1-CG1 4.5Å; F406-I410 HydrophobicContact CE1-CD1 3.5Å; F406-I410 VanDerWaalsContact CE1-CD1 3.5Å; F406-I410 HydrophobicContact CE1-CG1 4.3Å; F406-I410 HydrophobicContact CZ-CD1 4.16Å; F406-I410 WeakPolarHBondContact O-CG1 3.3Å; F406-I410 PolarHBondContact O-N 3.39Å
407	I	92.1	Very high	89.5	Confident	16 Å²	16	24.3 Å²	24.3	8%	0.082	12%	0.12	C	C	.	.	H	α-helix	trans	-64.4	-39.5	174.4	-70.8	-175.3	0	0	0	111.4	L362 Y363 I366 L403 Y404 T409 I410 T411	L362-I407 HydrophobicContact CB-CD1 3.78Å; Y363-I407 HydrophobicContact CD2-CG2 4.43Å; I366-I407 HydrophobicContact CB-CD1 4.37Å; I366-I407 HydrophobicContact CD1-CD1 3.19Å; I366-I407 HydrophobicContact CD1-CG1 3.99Å; I366-I407 HydrophobicContact CG1-CD1 3.6Å; L403-I407 WeakPolarHBondContact O-CG1 3.49Å; L403-I407 PolarHBondContact O-N 2.75Å; Y404-I407 PolarHBondContact O-N 3.27Å; I407-T409 VanDerWaalsContact C-N 3.28Å; I407-T409 PolarHBondContact O-N 3.25Å; I407-I410 PolarHBondContact O-N 3.15Å; I407-T411 WeakPolarHBondContact O-CB 3.19Å; I407-T411 PolarHBondContact O-N 3.03Å; I407-T411 PolarHBondContact O-OG1 2.88Å
408	L	91.1	Very high	88.7	Confident	6 Å²	6	24.6 Å²	24.6	3%	0.031	12%	0.123	C	C	.	.	H	α-helix	trans	-59.4	-42.4	174.1	-74.3	172.8	0	0	0	110.9	Y363 Y404 W405 F406 T411 S412	Y363-L408 HydrophobicContact CD2-CD2 4.26Å; Y363-L408 HydrophobicContact CE2-CD2 3.92Å; Y363-L408 HydrophobicContact CE2-CG 4.36Å; Y404-L408 HydrophobicContact CD1-CD1 4.12Å; Y404-L408 HydrophobicContact CE1-CD1 3.48Å; Y404-L408 VanDerWaalsContact CE1-CD1 3.48Å; Y404-L408 HydrophobicContact CE1-CG 4.46Å; Y404-L408 PolarHBondContact O-N 2.88Å; Y404-L408 VanDerWaalsContact O-N 3.14Å; W405-L408 HydrophobicContact CE3-CD1 3.98Å; W405-L408 HydrophobicContact CZ3-CD1 4.09Å; W405-L408 WeakPolarHBondContact O-CB 3.47Å; W405-L408 PolarHBondContact O-N 3.28Å; F406-L408 VanDerWaalsContact C-N 3.35Å; L408-T411 PolarHBondContact O-N 3.33Å; L408-S412 PolarHBondContact O-N 3.43Å; L408-S412 VanDerWaalsContact O-N 3.16Å
409	T	92.5	Very high	88	Confident	6 Å²	6	26.3 Å²	26.3	4%	0.037	13%	0.134	C	C	.	.	H	α-helix	trans	-57	-52.9	172.7	-48.6	0	0	0	0	110.9	S34 H38 W405 F406 I407 T411 S412 Y413	S34-T409 PolarHBondContact OG-OG1 3.1Å; H38-T409 PolarHBondContact CD2-OG1 3.39Å; H38-T409 PolarHBondContact CE1-N 3.36Å; H38-T409 PolarHBondContact CE1-OG1 2.96Å; H38-T409 VanDerWaalsContact CE1-OG1 3.28Å; H38-T409 PolarHBondContact NE2-OG1 3.15Å; W405-T409 PolarHBondContact O-N 3.25Å; W405-T409 PolarHBondContact O-OG1 2.86Å; W405-T409 VanDerWaalsContact O-OG1 3.06Å; F406-T409 VanDerWaalsContact O-CB 3.28Å; F406-T409 WeakPolarHBondContact O-CB 3.35Å; F406-T409 PolarHBondContact O-N 2.8Å; I407-T409 VanDerWaalsContact C-N 3.28Å; I407-T409 PolarHBondContact O-N 3.25Å; T409-T411 VanDerWaalsContact C-N 3.26Å; T409-T411 PolarHBondContact O-N 2.83Å; T409-S412 WeakPolarHBondContact O-CB 3.44Å; T409-S412 PolarHBondContact O-N 3.08Å; T409-S412 VanDerWaalsContact O-N 3.12Å; T409-Y413 HydrophobicContact CG2-CD2 3.93Å; T409-Y413 HydrophobicContact CG2-CE2 3.57Å; T409-Y413 WeakPolarHBondContact O-CD2 2.8Å; T409-Y413 PolarHBondContact O-N 2.97Å
410	I	91.8	Very high	87.1	Confident	67 Å²	67	28.6 Å²	28.6	34%	0.344	14%	0.144	S	C	.	.	H	α-helix	trans	-56.7	-42.2	179.7	-68.3	169.8	0	0	0	111.1	F406 I407 S412 Y413 V414	F406-I410 HydrophobicContact CD1-CD1 3.75Å; F406-I410 HydrophobicContact CD1-CG1 4.5Å; F406-I410 HydrophobicContact CE1-CD1 3.5Å; F406-I410 VanDerWaalsContact CE1-CD1 3.5Å; F406-I410 HydrophobicContact CE1-CG1 4.3Å; F406-I410 HydrophobicContact CZ-CD1 4.16Å; F406-I410 WeakPolarHBondContact O-CG1 3.3Å; F406-I410 PolarHBondContact O-N 3.39Å; I407-I410 PolarHBondContact O-N 3.15Å; I410-S412 VanDerWaalsContact C-N 3.3Å; I410-S412 PolarHBondContact O-N 3.44Å; I410-Y413 PolarHBondContact O-N 3.15Å; I410-Y413 VanDerWaalsContact O-N 3.14Å; I410-V414 HydrophobicContact CG2-CG2 4.16Å; I410-V414 WeakPolarHBondContact O-CG2 3.28Å; I410-V414 PolarHBondContact O-N 3.43Å
411	T	89.7	Confident	86.2	Confident	6 Å²	6	30.2 Å²	30.2	4%	0.037	16%	0.155	C	C	.	.	H	α-helix	trans	-59.7	-42	180	-59.1	0	0	0	0	111.1	F225 I407 L408 T409 V414 L415	F225-T411 HydrophobicContact CD2-CG2 3.95Å; F225-T411 HydrophobicContact CE2-CG2 3.49Å; F225-T411 VanDerWaalsContact CE2-CG2 3.49Å; F225-T411 HydrophobicContact CZ-CG2 4.09Å; I407-T411 WeakPolarHBondContact O-CB 3.19Å; I407-T411 PolarHBondContact O-N 3.03Å; I407-T411 PolarHBondContact O-OG1 2.88Å; L408-T411 PolarHBondContact O-N 3.33Å; T409-T411 VanDerWaalsContact C-N 3.26Å; T409-T411 PolarHBondContact O-N 2.83Å; T411-V414 PolarHBondContact O-N 2.88Å; T411-L415 WeakPolarHBondContact O-CG 3.46Å; T411-L415 PolarHBondContact O-N 2.9Å
412	S	89	Confident	85.5	Confident	0 Å²	0	30.2 Å²	30.2	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-60.5	-44.9	174.3	-172.2	0	0	0	0	112.5	W45 E174 L408 T409 I410 V414 L415 M416	W45-S412 PolarHBondContact NE1-OG 2.95Å; E174-S412 VanDerWaalsContact CD-OG 3.23Å; E174-S412 WeakPolarHBondContact OE1-CB 3.18Å; E174-S412 PolarHBondContact OE1-OG 2.89Å; L408-S412 PolarHBondContact O-N 3.43Å; L408-S412 VanDerWaalsContact O-N 3.16Å; T409-S412 WeakPolarHBondContact O-CB 3.44Å; T409-S412 PolarHBondContact O-N 3.08Å; T409-S412 VanDerWaalsContact O-N 3.12Å; I410-S412 VanDerWaalsContact C-N 3.3Å; I410-S412 PolarHBondContact O-N 3.44Å; S412-V414 PolarHBondContact O-N 3.35Å; S412-L415 WeakPolarHBondContact O-CB 3.35Å; S412-L415 PolarHBondContact O-N 2.94Å; S412-M416 PolarHBondContact O-N 3.16Å; S412-M416 VanDerWaalsContact O-N 3.09Å
413	Y	89.9	Confident	84.8	Confident	59 Å²	59	35 Å²	35	23%	0.231	17%	0.173	C	C	.	.	H	α-helix	trans	-64.5	-38.8	175.9	-76.4	-78.3	0	0	0	112.5	G37 I40 A41 L44 T409 I410 L415 M416 L417	G37-Y413 PolarHBondContact O-OH 2.55Å; I40-Y413 WeakPolarHBondContact CB-OH 3.45Å; I40-Y413 VanDerWaalsContact CG2-OH 3.26Å; I40-Y413 WeakPolarHBondContact CG2-OH 3.49Å; A41-Y413 HydrophobicContact CB-CE2 4.05Å; A41-Y413 PolarHBondContact N-OH 2.87Å; L44-Y413 HydrophobicContact CD1-CE1 4.29Å; T409-Y413 HydrophobicContact CG2-CD2 3.93Å; T409-Y413 HydrophobicContact CG2-CE2 3.57Å; T409-Y413 WeakPolarHBondContact O-CD2 2.8Å; T409-Y413 PolarHBondContact O-N 2.97Å; I410-Y413 PolarHBondContact O-N 3.15Å; I410-Y413 VanDerWaalsContact O-N 3.14Å; Y413-L415 VanDerWaalsContact C-N 3.33Å; Y413-L415 PolarHBondContact O-N 3.48Å; Y413-M416 HydrophobicContact CD1-CE 3.51Å; Y413-M416 HydrophobicContact CE1-CE 3.9Å; Y413-M416 PolarHBondContact O-N 3.4Å; Y413-L417 WeakPolarHBondContact O-CB 3.43Å; Y413-L417 VanDerWaalsContact O-CG 3.29Å; Y413-L417 WeakPolarHBondContact O-CG 3.43Å; Y413-L417 PolarHBondContact O-N 3.22Å
414	V	88.7	Confident	84.2	Confident	16 Å²	16	38.2 Å²	38.2	10%	0.097	19%	0.186	C	C	.	.	H	α-helix	trans	-63.8	-39.1	176	168.4	0	0	0	0	111.3	L355 M356 I410 T411 S412 M416 G418	L355-V414 HydrophobicContact CB-CG1 3.7Å; M356-V414 HydrophobicContact CG-CG1 4Å; I410-V414 HydrophobicContact CG2-CG2 4.16Å; I410-V414 WeakPolarHBondContact O-CG2 3.28Å; I410-V414 PolarHBondContact O-N 3.43Å; T411-V414 PolarHBondContact O-N 2.88Å; S412-V414 PolarHBondContact O-N 3.35Å; V414-M416 VanDerWaalsContact C-N 3.33Å; V414-M416 PolarHBondContact O-N 3.26Å; V414-G418 PolarHBondContact O-N 3.03Å
415	L	84.8	Confident	83.6	Confident	7 Å²	7	39.1 Å²	39.1	4%	0.037	19%	0.191	C	C	.	.	H	α-helix	trans	-61.5	-41.8	173.8	-71.4	172.8	0	0	0	111.7	W45 L228 M356 T411 S412 Y413 G418	W45-L415 HydrophobicContact CZ2-CB 3.85Å; L228-L415 HydrophobicContact CD1-CD1 4.12Å; L228-L415 HydrophobicContact CD1-CD2 4.44Å; L228-L415 HydrophobicContact CD2-CD2 3.79Å; M356-L415 HydrophobicContact SD-CD2 3.65Å; T411-L415 WeakPolarHBondContact O-CG 3.46Å; T411-L415 PolarHBondContact O-N 2.9Å; S412-L415 WeakPolarHBondContact O-CB 3.35Å; S412-L415 PolarHBondContact O-N 2.94Å; Y413-L415 VanDerWaalsContact C-N 3.33Å; Y413-L415 PolarHBondContact O-N 3.48Å; L415-G418 PolarHBondContact O-N 3.32Å
416	M	84.2	Confident	82.9	Confident	20 Å²	20	39.8 Å²	39.8	10%	0.099	20%	0.195	C	C	.	.	H	α-helix	trans	-70.1	-48.9	179.3	-176.1	178.5	62.4	0	0	112.5	L44 W45 S412 Y413 V414 G418 V422 I426	L44-M416 HydrophobicContact CB-SD 3.96Å; L44-M416 HydrophobicContact CD1-CE 3.77Å; L44-M416 HydrophobicContact CD1-SD 3.84Å; L44-M416 HydrophobicContact CG-SD 4.48Å; W45-M416 HydrophobicContact CZ2-CB 3.9Å; S412-M416 PolarHBondContact O-N 3.16Å; S412-M416 VanDerWaalsContact O-N 3.09Å; Y413-M416 HydrophobicContact CD1-CE 3.51Å; Y413-M416 HydrophobicContact CE1-CE 3.9Å; Y413-M416 PolarHBondContact O-N 3.4Å; V414-M416 VanDerWaalsContact C-N 3.33Å; V414-M416 PolarHBondContact O-N 3.26Å; M416-G418 PolarHBondContact O-N 3.04Å; M416-V422 HydrophobicContact CG-CG1 4.2Å; M416-I426 HydrophobicContact CG-CD1 3.54Å; M416-I426 HydrophobicContact SD-CD1 3.36Å; M416-I426 WeakPolarHBondContact SD-CD1 3.3Å
417	L	78.3	Confident	82.5	Confident	97 Å²	97	41.1 Å²	41.1	51%	0.508	20%	0.202	S	C	.	.	H	α-helix	trans	-63.3	-22.5	177.5	-70.8	174.6	0	0	0	112.1	Y413 T419	Y413-L417 WeakPolarHBondContact O-CB 3.43Å; Y413-L417 VanDerWaalsContact O-CG 3.29Å; Y413-L417 WeakPolarHBondContact O-CG 3.43Å; Y413-L417 PolarHBondContact O-N 3.22Å; L417-T419 PolarHBondContact O-N 2.76Å; L417-T419 VanDerWaalsContact O-N 3.17Å
418	G	69.6	Low	82	Confident	7 Å²	7	43.4 Å²	43.4	7%	0.072	22%	0.217	C	C	.	.	T	Hydrogen-bonded Turn	trans	-74.6	-2.7	-172.2	0	0	0	0	0	116.7	V352 V414 L415 M416	V352-G418 VanDerWaalsContact CG1-CA 3.46Å; V352-G418 WeakPolarHBondContact CG2-O 3.36Å; V414-G418 PolarHBondContact O-N 3.03Å; L415-G418 PolarHBondContact O-N 3.32Å; M416-G418 PolarHBondContact O-N 3.04Å
419	T	71.6	Confident	81.5	Confident	36 Å²	36	43.5 Å²	43.5	22%	0.221	22%	0.217	C	C	.	.			trans	-133	110.1	176.7	45.2	0	0	0	0	108.9	L417 T421 V422 R423	L417-T419 PolarHBondContact O-N 2.76Å; L417-T419 VanDerWaalsContact O-N 3.17Å; T419-T421 PolarHBondContact O-N 2.95Å; T419-T421 VanDerWaalsContact O-N 3.09Å; T419-V422 PolarHBondContact O-N 3.46Å; T419-V422 WeakPolarHBondContact OG1-CB 3.47Å; T419-V422 WeakPolarHBondContact OG1-CG2 3.43Å; T419-R423 PolarHBondContact O-N 3.27Å; T419-R423 VanDerWaalsContact O-N 3.09Å
420	M	71	Confident	81	Confident	96 Å²	96	46.8 Å²	46.8	47%	0.473	23%	0.234	S	C	.	.	H	α-helix	trans	-52.6	-34.7	179	-65.9	-62	-122	0	0	111.7	R423 H424	M420-R423 VanDerWaalsContact SD-CZ 3.56Å; M420-R423 PolarHBondContact SD-NH2 2.68Å; M420-H424 WeakPolarHBondContact O-CB 3.4Å; M420-H424 PolarHBondContact O-N 3.45Å
421	T	72.6	Confident	80.7	Confident	54 Å²	54	49.4 Å²	49.4	33%	0.331	25%	0.248	S	C	.	.	H	α-helix	trans	-65	-47.9	176	53.9	0	0	0	0	112	S161 T419 R423 H424 H425	S161-T421 WeakPolarHBondContact CB-OG1 3.46Å; S161-T421 WeakPolarHBondContact OG-CB 3.32Å; S161-T421 PolarHBondContact OG-OG1 3.31Å; T419-T421 PolarHBondContact O-N 2.95Å; T419-T421 VanDerWaalsContact O-N 3.09Å; T421-R423 VanDerWaalsContact C-N 3.32Å; T421-R423 PolarHBondContact O-N 2.97Å; T421-H424 PolarHBondContact O-N 2.86Å; T421-H425 VanDerWaalsContact O-CB 3.28Å; T421-H425 WeakPolarHBondContact O-CB 3.34Å; T421-H425 PolarHBondContact O-CD2 2.03Å; T421-H425 PolarHBondContact O-N 2.93Å; T421-H425 PolarHBondContact O-ND1 3.34Å
422	V	75.1	Confident	80.3	Confident	0 Å²	0	53.5 Å²	53.5	0%	0	27%	0.27	C	S	.	.	H	α-helix	trans	-60.8	-43.9	177.9	174.1	0	0	0	0	110.3	Y48 M416 T419 H424 H425 I426	Y48-V422 HydrophobicContact CD1-CG1 4.37Å; Y48-V422 HydrophobicContact CD2-CG1 4.03Å; Y48-V422 HydrophobicContact CE1-CG1 4.3Å; Y48-V422 HydrophobicContact CE1-CG2 4.1Å; Y48-V422 HydrophobicContact CE2-CB 4.17Å; Y48-V422 HydrophobicContact CE2-CG1 3.91Å; Y48-V422 HydrophobicContact CE2-CG2 4.07Å; Y48-V422 HydrophobicContact CG-CG1 4.27Å; M416-V422 HydrophobicContact CG-CG1 4.2Å; T419-V422 PolarHBondContact O-N 3.46Å; T419-V422 WeakPolarHBondContact OG1-CB 3.47Å; T419-V422 WeakPolarHBondContact OG1-CG2 3.43Å; V422-H424 PolarHBondContact O-N 3.46Å; V422-H425 WeakPolarHBondContact O-CB 3.24Å; V422-H425 PolarHBondContact O-N 2.93Å; V422-I426 HydrophobicContact CG1-CD1 3.64Å; V422-I426 HydrophobicContact CG1-CG1 4.19Å; V422-I426 WeakPolarHBondContact O-CB 3.41Å; V422-I426 VanDerWaalsContact O-CG1 3.3Å; V422-I426 WeakPolarHBondContact O-CG1 3.29Å; V422-I426 PolarHBondContact O-N 3.13Å
423	R	78.6	Confident	79.9	Confident	101 Å²	101	56.8 Å²	56.8	38%	0.381	29%	0.286	S	S	.	.	H	α-helix	trans	-59.7	-49.9	177.2	-173.1	176.3	67.9	-155.2	4.8	112.1	T419 M420 T421 H425 I426 Q427	T419-R423 PolarHBondContact O-N 3.27Å; T419-R423 VanDerWaalsContact O-N 3.09Å; M420-R423 VanDerWaalsContact SD-CZ 3.56Å; M420-R423 PolarHBondContact SD-NH2 2.68Å; T421-R423 VanDerWaalsContact C-N 3.32Å; T421-R423 PolarHBondContact O-N 2.97Å; R423-H425 VanDerWaalsContact C-N 3.27Å; R423-H425 PolarHBondContact O-N 3.34Å; R423-I426 PolarHBondContact O-N 3.12Å; R423-Q427 WeakPolarHBondContact O-CB 3.37Å; R423-Q427 WeakPolarHBondContact O-CG 3.2Å; R423-Q427 PolarHBondContact O-N 2.97Å
424	H	79.1	Confident	79.7	Confident	118 Å²	118	61.8 Å²	61.8	55%	0.546	31%	0.305	S	S	.	.	H	α-helix	trans	-59.8	-41.2	177.4	-175.3	-72.6	0	0	0	111.3	M420 T421 V422 Q427 T428	M420-H424 WeakPolarHBondContact O-CB 3.4Å; M420-H424 PolarHBondContact O-N 3.45Å; T421-H424 PolarHBondContact O-N 2.86Å; V422-H424 PolarHBondContact O-N 3.46Å; H424-Q427 PolarHBondContact O-N 3.22Å; H424-T428 PolarHBondContact CE1-OG1 3.12Å; H424-T428 PolarHBondContact ND1-OG1 3.37Å; H424-T428 WeakPolarHBondContact O-CB 3.45Å; H424-T428 PolarHBondContact O-N 3.35Å; H424-T428 PolarHBondContact O-OG1 3.01Å
425	H	78.8	Confident	79.5	Confident	32 Å²	32	67.6 Å²	67.6	15%	0.148	33%	0.326	C	S	.	.	H	α-helix	trans	-66	-44	178.8	-66.2	176.4	0	0	0	112.3	Y48 W52 T421 V422 R423 T428 I429	Y48-H425 HydrophobicContact CD2-CB 4.01Å; Y48-H425 HydrophobicContact CE2-CB 3.57Å; Y48-H425 AromaticContact CE2-ND1 3.77Å; W52-H425 AromaticContact CE2-CE1 3.83Å; W52-H425 AromaticContact CE2-CG 3.69Å; W52-H425 AromaticContact CE2-ND1 3.34Å; W52-H425 VanDerWaalsContact CE2-ND1 3.34Å; W52-H425 HydrophobicContact CZ2-CB 4.02Å; W52-H425 AromaticContact CZ2-CD2 3.57Å; W52-H425 AromaticContact CZ2-CE1 3.27Å; W52-H425 WeakPolarHBondContact CZ2-CE1 3.36Å; W52-H425 AromaticContact CZ2-CG 3.34Å; W52-H425 AromaticContact CZ2-ND1 3.17Å; W52-H425 WeakPolarHBondContact CZ2-ND1 3.46Å; W52-H425 AromaticContact CZ2-NE2 3.52Å; W52-H425 AromaticContact NE1-CG 3.48Å; W52-H425 AromaticContact NE1-ND1 3.17Å; W52-H425 PolarHBondContact NE1-ND1 2.79Å; W52-H425 VanDerWaalsContact NE1-ND1 3.17Å; T421-H425 VanDerWaalsContact O-CB 3.28Å; T421-H425 WeakPolarHBondContact O-CB 3.34Å; T421-H425 PolarHBondContact O-CD2 2.03Å; T421-H425 PolarHBondContact O-N 2.93Å; T421-H425 PolarHBondContact O-ND1 3.34Å; V422-H425 WeakPolarHBondContact O-CB 3.24Å; V422-H425 PolarHBondContact O-N 2.93Å; R423-H425 VanDerWaalsContact C-N 3.27Å; R423-H425 PolarHBondContact O-N 3.34Å; H425-T428 PolarHBondContact O-N 3.42Å; H425-I429 WeakPolarHBondContact O-CB 3.47Å; H425-I429 WeakPolarHBondContact O-CD1 3.1Å; H425-I429 WeakPolarHBondContact O-CG1 3.27Å; H425-I429 PolarHBondContact O-N 2.93Å
426	I	79.3	Confident	79.4	Confident	14 Å²	14	71.5 Å²	71.5	7%	0.072	35%	0.347	C	S	.	.	H	α-helix	trans	-61.2	-47.3	175.6	-71.8	174.1	0	0	0	110.1	L44 Y48 M416 V422 R423 T428 I429 L430	L44-I426 HydrophobicContact CD2-CG2 3.95Å; Y48-I426 HydrophobicContact CD2-CD1 4.44Å; Y48-I426 HydrophobicContact CD2-CG1 3.75Å; Y48-I426 HydrophobicContact CG-CD1 4.47Å; Y48-I426 HydrophobicContact CG-CG1 4.1Å; M416-I426 HydrophobicContact CG-CD1 3.54Å; M416-I426 HydrophobicContact SD-CD1 3.36Å; M416-I426 WeakPolarHBondContact SD-CD1 3.3Å; V422-I426 HydrophobicContact CG1-CD1 3.64Å; V422-I426 HydrophobicContact CG1-CG1 4.19Å; V422-I426 WeakPolarHBondContact O-CB 3.41Å; V422-I426 VanDerWaalsContact O-CG1 3.3Å; V422-I426 WeakPolarHBondContact O-CG1 3.29Å; V422-I426 PolarHBondContact O-N 3.13Å; R423-I426 PolarHBondContact O-N 3.12Å; I426-T428 VanDerWaalsContact C-N 3.31Å; I426-T428 PolarHBondContact O-N 3.17Å; I426-I429 PolarHBondContact O-N 3.46Å; I426-L430 HydrophobicContact CG2-CD1 3.75Å; I426-L430 HydrophobicContact CG2-CG 4.23Å; I426-L430 WeakPolarHBondContact O-CB 3.12Å; I426-L430 VanDerWaalsContact O-CG 3.31Å; I426-L430 WeakPolarHBondContact O-CG 3.42Å; I426-L430 PolarHBondContact O-N 3.23Å
427	Q	84	Confident	79.5	Confident	105 Å²	105	75.3 Å²	75.3	49%	0.491	37%	0.366	S	S	.	.	H	α-helix	trans	-57.8	-44.7	175.9	-73.5	175	-30.4	0	0	111.6	R423 H424 L430 L431	R423-Q427 WeakPolarHBondContact O-CB 3.37Å; R423-Q427 WeakPolarHBondContact O-CG 3.2Å; R423-Q427 PolarHBondContact O-N 2.97Å; H424-Q427 PolarHBondContact O-N 3.22Å; Q427-L430 PolarHBondContact O-N 3.39Å; Q427-L431 WeakPolarHBondContact O-CB 3.45Å; Q427-L431 VanDerWaalsContact O-CG 3.29Å; Q427-L431 WeakPolarHBondContact O-CG 3.42Å; Q427-L431 PolarHBondContact O-N 3.02Å
428	T	82.1	Confident	79.8	Confident	65 Å²	65	79 Å²	79	40%	0.399	37%	0.374	S	S	.	.	H	α-helix	trans	-63.4	-43.9	178.1	-54	0	0	0	0	111.6	H424 H425 I426 L432	H424-T428 PolarHBondContact CE1-OG1 3.12Å; H424-T428 PolarHBondContact ND1-OG1 3.37Å; H424-T428 WeakPolarHBondContact O-CB 3.45Å; H424-T428 PolarHBondContact O-N 3.35Å; H424-T428 PolarHBondContact O-OG1 3.01Å; H425-T428 PolarHBondContact O-N 3.42Å; I426-T428 VanDerWaalsContact C-N 3.31Å; I426-T428 PolarHBondContact O-N 3.17Å; T428-L432 WeakPolarHBondContact O-CB 3.42Å; T428-L432 PolarHBondContact O-N 3.05Å
429	I	81.1	Confident	80.3	Confident	8 Å²	8	83.1 Å²	83.1	4%	0.041	39%	0.394	C	S	.	.	H	α-helix	trans	-67.5	-43.2	179.7	-66.9	163.6	0	0	0	110.6	T47 I55 H425 I426 L432 I433	T47-I429 HydrophobicContact CG2-CG2 3.54Å; I55-I429 HydrophobicContact CD1-CD1 4.42Å; I55-I429 HydrophobicContact CD1-CG1 3.94Å; H425-I429 WeakPolarHBondContact O-CB 3.47Å; H425-I429 WeakPolarHBondContact O-CD1 3.1Å; H425-I429 WeakPolarHBondContact O-CG1 3.27Å; H425-I429 PolarHBondContact O-N 2.93Å; I426-I429 PolarHBondContact O-N 3.46Å; I429-L432 PolarHBondContact O-N 3.26Å; I429-I433 HydrophobicContact CG2-CD1 3.86Å; I429-I433 HydrophobicContact CG2-CG1 4.45Å; I429-I433 WeakPolarHBondContact O-CG1 3.4Å; I429-I433 PolarHBondContact O-N 2.96Å
430	L	82	Confident	80.3	Confident	75 Å²	75	92 Å²	92	39%	0.393	42%	0.424	S	S	.	.	H	α-helix	trans	-63.1	-42.9	176.6	-73.1	174.8	0	0	0	111.8	L44 I426 Q427 L432 I433 W434	L44-L430 HydrophobicContact CD2-CD1 4.05Å; I426-L430 HydrophobicContact CG2-CD1 3.75Å; I426-L430 HydrophobicContact CG2-CG 4.23Å; I426-L430 WeakPolarHBondContact O-CB 3.12Å; I426-L430 VanDerWaalsContact O-CG 3.31Å; I426-L430 WeakPolarHBondContact O-CG 3.42Å; I426-L430 PolarHBondContact O-N 3.23Å; Q427-L430 PolarHBondContact O-N 3.39Å; L430-L432 VanDerWaalsContact C-N 3.32Å; L430-L432 PolarHBondContact O-N 2.9Å; L430-I433 PolarHBondContact O-N 3.32Å; L430-W434 VanDerWaalsContact O-CB 3.3Å; L430-W434 WeakPolarHBondContact O-CB 3.36Å; L430-W434 PolarHBondContact O-N 3.06Å
431	L	84.2	Confident	79.7	Confident	121 Å²	121	96.9 Å²	96.9	63%	0.634	45%	0.452	S	S	*	.	H	α-helix	trans	-61.1	-40.4	174	-78.2	166.2	0	0	0	111.8	Q427 W434 Y435	Q427-L431 WeakPolarHBondContact O-CB 3.45Å; Q427-L431 VanDerWaalsContact O-CG 3.29Å; Q427-L431 WeakPolarHBondContact O-CG 3.42Å; Q427-L431 PolarHBondContact O-N 3.02Å; L431-W434 PolarHBondContact O-N 3.44Å; L431-Y435 VanDerWaalsContact O-CB 3.22Å; L431-Y435 WeakPolarHBondContact O-CB 3.45Å; L431-Y435 PolarHBondContact O-N 3.39Å
432	L	81.6	Confident	80	Confident	93 Å²	93	99 Å²	99	49%	0.487	46%	0.458	S	S	.	.	H	α-helix	trans	-66.7	-40.9	177.2	-170.4	114.4	0	0	0	112.1	T428 I429 L430 N436	T428-L432 WeakPolarHBondContact O-CB 3.42Å; T428-L432 PolarHBondContact O-N 3.05Å; I429-L432 PolarHBondContact O-N 3.26Å; L430-L432 VanDerWaalsContact C-N 3.32Å; L430-L432 PolarHBondContact O-N 2.9Å; L432-N436 WeakPolarHBondContact O-CB 3.37Å; L432-N436 VanDerWaalsContact O-CG 3.26Å; L432-N436 PolarHBondContact O-N 3.29Å; L432-N436 PolarHBondContact O-ND2 3.15Å
433	I	82.1	Confident	80.3	Confident	69 Å²	69	104.2 Å²	104.2	35%	0.354	48%	0.482	S	S	.	.	H	α-helix	trans	-64.1	-49.1	174.7	-68.9	166.7	0	0	0	109.9	T47 I429 L430 Y435 N436 I437	T47-I433 HydrophobicContact CG2-CD1 3.7Å; I429-I433 HydrophobicContact CG2-CD1 3.86Å; I429-I433 HydrophobicContact CG2-CG1 4.45Å; I429-I433 WeakPolarHBondContact O-CG1 3.4Å; I429-I433 PolarHBondContact O-N 2.96Å; L430-I433 PolarHBondContact O-N 3.32Å; I433-Y435 PolarHBondContact O-N 2.91Å; I433-N436 PolarHBondContact O-N 3.47Å; I433-I437 HydrophobicContact CG2-CD1 3.8Å; I433-I437 HydrophobicContact CG2-CG1 4.49Å; I433-I437 WeakPolarHBondContact O-CG1 3.34Å; I433-I437 PolarHBondContact O-N 3.13Å
434	W	85.6	Confident	80.4	Confident	164 Å²	164	104.4 Å²	104.4	62%	0.621	49%	0.487	S	S	*	.	H	α-helix	trans	-57.7	-47	177.9	-177.3	-94.4	0	0	0	111.8	L430 L431 N436 I437 W438	L430-W434 VanDerWaalsContact O-CB 3.3Å; L430-W434 WeakPolarHBondContact O-CB 3.36Å; L430-W434 PolarHBondContact O-N 3.06Å; L431-W434 PolarHBondContact O-N 3.44Å; W434-N436 VanDerWaalsContact C-N 3.35Å; W434-N436 PolarHBondContact O-N 3.26Å; W434-I437 PolarHBondContact O-N 3.04Å; W434-W438 WeakPolarHBondContact O-CB 3.44Å; W434-W438 PolarHBondContact O-N 3.39Å
435	Y	84.5	Confident	80.5	Confident	138 Å²	138	103.6 Å²	103.6	54%	0.541	48%	0.484	S	S	.	.	H	α-helix	trans	-59.5	-42.9	176.3	-178.8	-98.9	0	0	0	112.3	L431 I433 I437 W438 N439	L431-Y435 VanDerWaalsContact O-CB 3.22Å; L431-Y435 WeakPolarHBondContact O-CB 3.45Å; L431-Y435 PolarHBondContact O-N 3.39Å; I433-Y435 PolarHBondContact O-N 2.91Å; Y435-I437 VanDerWaalsContact C-N 3.34Å; Y435-I437 PolarHBondContact O-N 3.48Å; Y435-W438 PolarHBondContact O-N 3.47Å; Y435-N439 WeakPolarHBondContact CE1-ND2 3.46Å; Y435-N439 WeakPolarHBondContact O-CB 3.46Å; Y435-N439 PolarHBondContact O-N 3.45Å; Y435-N439 PolarHBondContact OH-ND2 3.03Å
436	N	83	Confident	80.6	Confident	89 Å²	89	108.1 Å²	108.1	48%	0.476	51%	0.505	S	S	.	.	H	α-helix	trans	-69.9	-29.1	178.2	-74.6	-25.6	0	0	0	113.6	L432 I433 W434	L432-N436 WeakPolarHBondContact O-CB 3.37Å; L432-N436 VanDerWaalsContact O-CG 3.26Å; L432-N436 PolarHBondContact O-N 3.29Å; L432-N436 PolarHBondContact O-ND2 3.15Å; I433-N436 PolarHBondContact O-N 3.47Å; W434-N436 VanDerWaalsContact C-N 3.35Å; W434-N436 PolarHBondContact O-N 3.26Å
437	I	85.5	Confident	80.7	Confident	99 Å²	99	114.3 Å²	114.3	51%	0.508	53%	0.534	S	S	.	.	H	α-helix	trans	-71.4	-49	172.5	-68.2	167.6	0	0	0	109.1	I433 W434 Y435 N439 R440	I433-I437 HydrophobicContact CG2-CD1 3.8Å; I433-I437 HydrophobicContact CG2-CG1 4.49Å; I433-I437 WeakPolarHBondContact O-CG1 3.34Å; I433-I437 PolarHBondContact O-N 3.13Å; W434-I437 PolarHBondContact O-N 3.04Å; Y435-I437 VanDerWaalsContact C-N 3.34Å; Y435-I437 PolarHBondContact O-N 3.48Å; I437-N439 PolarHBondContact O-N 3.5Å; I437-R440 WeakPolarHBondContact O-CB 3.35Å; I437-R440 PolarHBondContact O-N 3.38Å; I437-R440 VanDerWaalsContact O-N 3.16Å
438	W	84.3	Confident	80.4	Confident	174 Å²	174	115 Å²	115	66%	0.659	54%	0.537	S	S	*	.	H	α-helix	trans	-63.8	-37.4	-178.6	-170.8	-88.5	0	0	0	113.5	W434 Y435 R440	W434-W438 WeakPolarHBondContact O-CB 3.44Å; W434-W438 PolarHBondContact O-N 3.39Å; Y435-W438 PolarHBondContact O-N 3.47Å; W438-R440 PolarHBondContact O-N 3.48Å
439	N	81.3	Confident	80.3	Confident	95 Å²	95	118.8 Å²	118.8	51%	0.508	55%	0.548	S	S	.	.	T	Hydrogen-bonded Turn	trans	-79.4	-0.9	177.7	-93.9	20.7	0	0	0	114.2	Y435 I437	Y435-N439 WeakPolarHBondContact CE1-ND2 3.46Å; Y435-N439 WeakPolarHBondContact O-CB 3.46Å; Y435-N439 PolarHBondContact O-N 3.45Å; Y435-N439 PolarHBondContact OH-ND2 3.03Å; I437-N439 PolarHBondContact O-N 3.5Å
440	R	71.5	Confident	80.2	Confident	222 Å²	222	128.1 Å²	128.1	84%	0.838	59%	0.59	S	S	*	*	T	Hydrogen-bonded Turn	trans	-90.1	-15.3	176.9	-100.6	-176.8	164.2	-164.8	-6.2	113.2	I437 W438	I437-R440 WeakPolarHBondContact O-CB 3.35Å; I437-R440 PolarHBondContact O-N 3.38Å; I437-R440 VanDerWaalsContact O-N 3.16Å; W438-R440 PolarHBondContact O-N 3.48Å
441	D	57.2	Low	80.1	Confident	198 Å²	198	132.9 Å²	132.9	100%	1.059	61%	0.608	S	S	*	*			trans	-101.9	0	167.4	-58	-30.1	0	0	0	109.2

Retrieved 441 of 441 residues in 181.1 ms (Link to these results)

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