A0A5K4FAB0_SCHMA Loading...

Protein lifeguard 4

AlphaFold DB , UniProt , Accession A0A5K4FAB0, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 387 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	37.1	Very low	32.6	Very low	86 Å²	86	116.7 Å²	116.7	42%	0.424	62%	0.624	S	S	.	*				0	115	0	-74	178.9	177	0	0	109.7	H3 P101 D226	M1-H3 WeakPolarHBondContact CB-NE2 3.41Å; M1-H3 PolarHBondContact O-N 3.29Å; M1-H3 PolarHBondContact SD-NE2 3.31Å; M1-P101 HydrophobicContact CE-CB 4.25Å; M1-D226 PolarHBondContact N-OD1 2.99Å; M1-D226 PolarHBondContact N-OD2 3.2Å
2	L	31.9	Very low	32.1	Very low	58 Å²	58	119 Å²	119	30%	0.304	63%	0.634	S	S	.	*			trans	-84	108	170.2	-65	161.2	0	0	0	108.1	I213 M220	L2-I213 HydrophobicContact CD2-CD1 4.38Å; L2-I213 HydrophobicContact CD2-CG2 3.8Å; L2-M220 HydrophobicContact CB-CB 4.19Å; L2-M220 HydrophobicContact CB-CG 4.27Å; L2-M220 HydrophobicContact CB-SD 3.81Å; L2-M220 HydrophobicContact CD1-SD 3.84Å; L2-M220 HydrophobicContact CD2-CB 3.56Å; L2-M220 HydrophobicContact CD2-CG 4.4Å; L2-M220 HydrophobicContact CD2-SD 4.23Å; L2-M220 HydrophobicContact CG-CB 4.36Å; L2-M220 HydrophobicContact CG-SD 4.14Å
3	H	33.7	Very low	31.7	Very low	66 Å²	66	124.8 Å²	124.8	31%	0.306	64%	0.644	S	S	.	*	P	Polyproline II helix	trans	-94.6	127.6	175.3	-75.6	-82.4	0	0	0	109.5	M1 R223	M1-H3 WeakPolarHBondContact CB-NE2 3.41Å; M1-H3 PolarHBondContact O-N 3.29Å; M1-H3 PolarHBondContact SD-NE2 3.31Å; H3-R223 PolarHBondContact CD2-NE 2.95Å; H3-R223 PolarHBondContact CD2-NH2 3.1Å; H3-R223 PolarHBondContact CE1-NH2 3.49Å; H3-R223 VanDerWaalsContact CE1-NH2 3.31Å; H3-R223 PolarHBondContact NE2-NE 3.17Å; H3-R223 PolarHBondContact NE2-NH2 3.1Å
4	K	32.6	Very low	31.5	Very low	162 Å²	162	125.1 Å²	125.1	70%	0.704	65%	0.647	S	S	*	*	P	Polyproline II helix	trans	-80.1	138.5	168.8	-157.7	177.1	-174.1	-175.7	0	108.6
5	Y	34.8	Very low	31.3	Very low	97 Å²	97	126.7 Å²	126.7	38%	0.38	66%	0.657	S	S	.	*	P	Polyproline II helix	trans	-55.7	135.8	173.6	-94.5	-90.1	0	0	0	111.1	N7 I25 R218	Y5-N7 PolarHBondContact O-N 3.17Å; Y5-I25 HydrophobicContact CD1-CD1 3.51Å; Y5-I25 HydrophobicContact CD1-CG1 4.07Å; Y5-I25 HydrophobicContact CE1-CD1 3.6Å; Y5-I25 HydrophobicContact CE1-CG1 3.59Å; Y5-R218 WeakPolarHBondContact CD2-O 3.4Å; Y5-R218 WeakPolarHBondContact CE2-O 3.32Å
6	P	37.2	Very low	31	Very low	116 Å²	116	132.9 Å²	132.9	75%	0.753	67%	0.669	S	S	*	*			trans	-79.6	106.5	167.5	30.7	-27.4	0	0	0	108.8
7	N	30.3	Very low	30.8	Very low	136 Å²	136	133.8 Å²	133.8	73%	0.727	67%	0.674	S	S	*	*			trans	-87.7	105.4	164.3	-87.4	-5.2	0	0	0	108.1	Y5	Y5-N7 PolarHBondContact O-N 3.17Å
8	E	32.3	Very low	30.5	Very low	201 Å²	201	136.2 Å²	136.2	94%	0.939	68%	0.68	S	S	*	*			trans	-171.7	127.1	158.3	-108.4	166.5	-144.9	0	0	111
9	G	30.5	Very low	30.2	Very low	75 Å²	75	136.4 Å²	136.4	77%	0.773	69%	0.694	S	S	*	*			trans	106.4	99.7	146.7	0	0	0	0	0	118.1
10	S	26.8	Very low	30.1	Very low	97 Å²	97	136.2 Å²	136.2	68%	0.678	69%	0.694	S	S	*	*			trans	-19	140.5	151.1	55.1	0	0	0	0	116.9
11	H	31.4	Very low	30.1	Very low	190 Å²	190	139.2 Å²	139.2	88%	0.88	71%	0.706	S	S	*	*				-172.9	136.1	123.6	-88.3	-57.5	0	0	0	112.1
12	I	26.7	Very low	29.6	Very low	144 Å²	144	143.7 Å²	143.7	74%	0.738	73%	0.726	S	S	*	*			trans	-85.3	136	174.9	-54.5	163.2	0	0	0	108.1
13	Y	26.8	Very low	29.6	Very low	195 Å²	195	147 Å²	147	77%	0.765	74%	0.743	S	S	*	*				156	132.8	123.6	-103.1	-79.9	0	0	0	116.1
14	N	28.6	Very low	29.3	Very low	129 Å²	129	149.6 Å²	149.6	69%	0.69	76%	0.763	S	S	*	*			trans	56.4	118.2	145	-81.7	-1.5	0	0	0	123.3	R16	N14-R16 PolarHBondContact O-N 3.33Å
15	D	28.8	Very low	29.1	Very low	149 Å²	149	146.3 Å²	146.3	80%	0.797	75%	0.752	S	S	*	*				20	93.4	127.7	-77	-12.5	0	0	0	116.9
16	R	26.6	Very low	28.7	Very low	225 Å²	225	145.5 Å²	145.5	85%	0.849	76%	0.76	S	S	*	*				158.5	123.3	126.2	-86.6	168	-163.8	-159.9	5.6	109.3	N14	N14-R16 PolarHBondContact O-N 3.33Å
17	I	27.3	Very low	28.4	Very low	148 Å²	148	148.6 Å²	148.6	76%	0.759	76%	0.764	S	S	*	*			trans	83.2	128.8	146.3	-59.2	161.7	0	0	0	117
18	K	26.4	Very low	28.3	Very low	177 Å²	177	149.8 Å²	149.8	77%	0.77	77%	0.77	S	S	*	*			trans	85.8	96.3	163.2	-77.4	164.4	-176.9	-175.9	0	117.8	N20	K18-N20 VanDerWaalsContact C-N 3.3Å; K18-N20 PolarHBondContact O-N 2.61Å
19	C	24.6	Very low	28.2	Very low	140 Å²	140	143.3 Å²	143.3	95%	0.946	75%	0.747	S	S	*	*			trans	-58.2	91	153.4	-66.9	0	0	0	0	110
20	N	27.7	Very low	28.1	Very low	132 Å²	132	147.9 Å²	147.9	71%	0.706	75%	0.746	S	S	*	*			trans	-113.4	118.6	158.4	-92.2	-1.4	0	0	0	107.2	K18 Q22	K18-N20 VanDerWaalsContact C-N 3.3Å; K18-N20 PolarHBondContact O-N 2.61Å; N20-Q22 PolarHBondContact O-N 3.17Å
21	E	29.4	Very low	28.5	Very low	200 Å²	200	147.3 Å²	147.3	94%	0.935	74%	0.735	S	S	*	*	S	Bend	trans	14.1	74.5	155	-60.7	-178.3	158.6	0	0	117
22	Q	27.6	Very low	28.4	Very low	181 Å²	181	142.8 Å²	142.8	85%	0.846	72%	0.724	S	S	*	*			trans	-137	118.9	163.1	-78.6	-172.7	-21	0	0	109.7	N20 V24	N20-Q22 PolarHBondContact O-N 3.17Å; Q22-V24 PolarHBondContact O-N 3.32Å
23	I	32.2	Very low	28.6	Very low	128 Å²	128	139.3 Å²	139.3	66%	0.656	72%	0.724	S	S	*	*			trans	-71.5	113.1	179	-66.3	167.8	0	0	0	107.7	I25	I23-I25 PolarHBondContact O-N 3.12Å
24	V	26.9	Very low	28.9	Very low	119 Å²	119	139 Å²	139	72%	0.721	73%	0.732	S	S	*	*			trans	-69.7	114.9	168.3	177.6	0	0	0	0	107.8	Q22 C26	Q22-V24 PolarHBondContact O-N 3.32Å; V24-C26 PolarHBondContact O-N 3.13Å
25	I	28.1	Very low	30	Very low	93 Å²	93	136.9 Å²	136.9	48%	0.477	72%	0.719	S	S	.	*			trans	-77.4	101	166.8	-59.3	172.6	0	0	0	106.3	Y5 I23 E27	Y5-I25 HydrophobicContact CD1-CD1 3.51Å; Y5-I25 HydrophobicContact CD1-CG1 4.07Å; Y5-I25 HydrophobicContact CE1-CD1 3.6Å; Y5-I25 HydrophobicContact CE1-CG1 3.59Å; I23-I25 PolarHBondContact O-N 3.12Å; I25-E27 PolarHBondContact O-N 3.07Å
26	C	27.1	Very low	31.4	Very low	81 Å²	81	133 Å²	133	55%	0.547	70%	0.699	S	S	.	*			trans	-82.8	107.1	168.1	-75.1	0	0	0	0	108.9	V24 D28	V24-C26 PolarHBondContact O-N 3.13Å; C26-D28 PolarHBondContact O-N 3.13Å; C26-D28 VanDerWaalsContact O-N 3.12Å
27	E	30.2	Very low	33	Very low	181 Å²	181	126.4 Å²	126.4	85%	0.846	69%	0.685	S	S	*	*	T	Hydrogen-bonded Turn	trans	-66.3	-2.2	173.8	-88.3	-178.8	150	0	0	114.4	I25	I25-E27 PolarHBondContact O-N 3.07Å
28	D	29.2	Very low	34.7	Very low	161 Å²	161	125 Å²	125	86%	0.861	67%	0.674	S	S	*	*	T	Hydrogen-bonded Turn	trans	-127	14.1	-179.7	-82.8	-35	0	0	0	115	C26 K30	C26-D28 PolarHBondContact O-N 3.13Å; C26-D28 VanDerWaalsContact O-N 3.12Å; D28-K30 PolarHBondContact O-N 3.43Å
29	S	29.1	Very low	36.7	Very low	64 Å²	64	120 Å²	120	45%	0.448	65%	0.65	S	S	.	*			trans	-72.5	109.6	178.8	70	0	0	0	0	109.9	L31	S29-L31 PolarHBondContact O-N 3.17Å
30	K	29.1	Very low	38.8	Very low	171 Å²	171	117.3 Å²	117.3	74%	0.743	63%	0.625	S	S	*	*			trans	-34.6	140	147.6	-70.4	178.7	173.9	177.6	0	107.7	D28 S32	D28-K30 PolarHBondContact O-N 3.43Å; K30-S32 PolarHBondContact O-N 3.22Å
31	L	35.2	Very low	40.8	Very low	86 Å²	86	117.8 Å²	117.8	45%	0.45	62%	0.617	S	S	.	*	S	Bend	trans	-66.2	31.9	169.7	-142.7	90.6	0	0	0	111.8	S29 I153 Y215	S29-L31 PolarHBondContact O-N 3.17Å; L31-I153 WeakPolarHBondContact CD2-O 3.14Å; L31-Y215 HydrophobicContact CD2-CD1 4.43Å; L31-Y215 HydrophobicContact CD2-CE1 4.26Å
32	S	28.2	Very low	42.8	Very low	94 Å²	94	109.2 Å²	109.2	66%	0.657	58%	0.577	S	S	*	*			trans	-130.5	119.9	-170.8	172.9	0	0	0	0	107.1	K30	K30-S32 PolarHBondContact O-N 3.22Å
33	G	31.5	Very low	45	Very low	71 Å²	71	101.5 Å²	101.5	73%	0.732	54%	0.541	S	S	*	.	S	Bend	trans	119.2	40.7	152.1	0	0	0	0	0	117.9
34	M	33.6	Very low	47.1	Very low	190 Å²	190	97.9 Å²	97.9	94%	0.936	52%	0.523	S	S	*	.			trans	173.9	94.5	135.6	-101.9	178.3	142.9	0	0	107.8	D36	M34-D36 PolarHBondContact O-N 3.04Å
35	I	51.5	Low	49.3	Very low	83 Å²	83	96.9 Å²	96.9	43%	0.426	51%	0.509	S	S	.	.			trans	-67.8	109	169.2	-43	177.6	0	0	0	106.2	P37 I40 Y215	I35-P37 WeakPolarHBondContact O-CD 3.44Å; I35-P37 VanDerWaalsContact O-N 3.08Å; I35-I40 HydrophobicContact CB-CD1 3.79Å; I35-I40 HydrophobicContact CB-CG1 4.04Å; I35-I40 HydrophobicContact CD1-CD1 4.38Å; I35-I40 HydrophobicContact CG2-CD1 3.62Å; I35-I40 HydrophobicContact CG2-CG1 3.26Å; I35-Y215 HydrophobicContact CD1-CE2 4.38Å; I35-Y215 HydrophobicContact CG2-CE2 4.48Å
36	D	57.6	Low	51.5	Low	68 Å²	68	92.4 Å²	92.4	36%	0.364	49%	0.486	S	S	.	.			trans	-52.9	120.2	174.4	178.6	-2.7	0	0	0	106.9	M34 K38 R39 I40 R224	M34-D36 PolarHBondContact O-N 3.04Å; D36-K38 PolarHBondContact O-N 3.08Å; D36-K38 WeakPolarHBondContact OD1-CB 3.43Å; D36-K38 WeakPolarHBondContact OD1-CG 3.43Å; D36-K38 PolarHBondContact OD1-N 2.95Å; D36-R39 HydrophobicContact CB-CB 4.24Å; D36-R39 WeakPolarHBondContact O-CA 3.21Å; D36-R39 WeakPolarHBondContact O-CB 3.26Å; D36-R39 PolarHBondContact O-N 3.45Å; D36-I40 PolarHBondContact O-N 2.9Å; D36-R224 IonicContact OD2-NH2 2.99Å; D36-R224 PolarHBondContact OD2-NH2 3.29Å
37	P	60.3	Low	54	Low	86 Å²	86	90.5 Å²	90.5	56%	0.558	47%	0.468	S	S	*	.	H	α-helix	trans	-53.4	-26.4	179.2	18.9	-31.7	0	0	0	111.8	I35 R41	I35-P37 WeakPolarHBondContact O-CD 3.44Å; I35-P37 VanDerWaalsContact O-N 3.08Å; P37-R41 WeakPolarHBondContact O-CG 3.34Å; P37-R41 PolarHBondContact O-N 3.06Å; P37-R41 VanDerWaalsContact O-N 3.12Å
38	K	64.1	Low	56.2	Low	120 Å²	120	83.2 Å²	83.2	52%	0.522	44%	0.435	S	S	.	.	H	α-helix	trans	-69.1	-33.1	174.4	-60.6	177.7	178.9	178.2	0	112.8	D36 F42	D36-K38 PolarHBondContact O-N 3.08Å; D36-K38 WeakPolarHBondContact OD1-CB 3.43Å; D36-K38 WeakPolarHBondContact OD1-CG 3.43Å; D36-K38 PolarHBondContact OD1-N 2.95Å; K38-F42 PolarHBondContact O-N 3.42Å; K38-F42 VanDerWaalsContact O-N 3.11Å
39	R	67.2	Low	58.4	Low	71 Å²	71	77.1 Å²	77.1	27%	0.268	40%	0.403	S	S	.	.	H	α-helix	trans	-75	-38.5	176.1	-169.5	-179.4	-78.7	-101.2	11.1	111.6	D36 R41 F42 I43 L214 Y215 G216	D36-R39 HydrophobicContact CB-CB 4.24Å; D36-R39 WeakPolarHBondContact O-CA 3.21Å; D36-R39 WeakPolarHBondContact O-CB 3.26Å; D36-R39 PolarHBondContact O-N 3.45Å; R39-R41 VanDerWaalsContact C-N 3.3Å; R39-R41 PolarHBondContact O-N 3.06Å; R39-F42 WeakPolarHBondContact O-CB 3.34Å; R39-F42 PolarHBondContact O-N 2.98Å; R39-F42 VanDerWaalsContact O-N 3.15Å; R39-I43 HydrophobicContact CG-CD1 4.26Å; R39-I43 WeakPolarHBondContact O-CG1 3.45Å; R39-I43 PolarHBondContact O-N 3.2Å; R39-L214 PolarHBondContact NH1-O 3.4Å; R39-L214 VanDerWaalsContact NH1-O 3.1Å; R39-Y215 WeakPolarHBondContact CD-O 3.4Å; R39-Y215 VanDerWaalsContact NH1-C 3.32Å; R39-Y215 PolarHBondContact NH1-O 3.23Å; R39-G216 VanDerWaalsContact NH1-N 3.12Å
40	I	69.6	Low	60.6	Low	83 Å²	83	74.6 Å²	74.6	43%	0.426	39%	0.385	S	S	.	.	H	α-helix	trans	-56.8	-48	170.9	-66	170.3	0	0	0	110	I35 D36 F42 I43 L44	I35-I40 HydrophobicContact CB-CD1 3.79Å; I35-I40 HydrophobicContact CB-CG1 4.04Å; I35-I40 HydrophobicContact CD1-CD1 4.38Å; I35-I40 HydrophobicContact CG2-CD1 3.62Å; I35-I40 HydrophobicContact CG2-CG1 3.26Å; D36-I40 PolarHBondContact O-N 2.9Å; I40-F42 VanDerWaalsContact C-N 3.29Å; I40-F42 PolarHBondContact O-N 3.36Å; I40-I43 PolarHBondContact O-N 3.4Å; I40-L44 WeakPolarHBondContact O-CB 3.45Å; I40-L44 PolarHBondContact O-N 3.46Å
41	R	69.1	Low	62.9	Low	142 Å²	142	68 Å²	68	54%	0.536	36%	0.358	S	S	.	.	H	α-helix	trans	-60.3	-39	177.4	-72.9	-178.5	-168.3	-168.8	2.7	112.4	P37 R39 L44 K45	P37-R41 WeakPolarHBondContact O-CG 3.34Å; P37-R41 PolarHBondContact O-N 3.06Å; P37-R41 VanDerWaalsContact O-N 3.12Å; R39-R41 VanDerWaalsContact C-N 3.3Å; R39-R41 PolarHBondContact O-N 3.06Å; R41-L44 PolarHBondContact O-N 3.33Å; R41-K45 VanDerWaalsContact O-CG 3.3Å; R41-K45 WeakPolarHBondContact O-CG 3.49Å; R41-K45 PolarHBondContact O-N 2.76Å
42	F	71	Confident	64.9	Low	20 Å²	20	68.4 Å²	68.4	9%	0.088	36%	0.36	C	S	.	.	H	α-helix	trans	-62.3	-50.8	176.1	177.9	-95.7	0	0	0	111.7	K38 R39 I40 L44 K45 V46 L214 Y222 F227 A230	K38-F42 PolarHBondContact O-N 3.42Å; K38-F42 VanDerWaalsContact O-N 3.11Å; R39-F42 WeakPolarHBondContact O-CB 3.34Å; R39-F42 PolarHBondContact O-N 2.98Å; R39-F42 VanDerWaalsContact O-N 3.15Å; I40-F42 VanDerWaalsContact C-N 3.29Å; I40-F42 PolarHBondContact O-N 3.36Å; F42-L44 VanDerWaalsContact C-N 3.32Å; F42-L44 PolarHBondContact O-N 3.31Å; F42-K45 WeakPolarHBondContact O-CB 3.4Å; F42-K45 PolarHBondContact O-N 2.97Å; F42-V46 HydrophobicContact CE1-CG2 4.28Å; F42-V46 HydrophobicContact CZ-CG2 4.46Å; F42-V46 PolarHBondContact O-N 3.24Å; F42-V46 VanDerWaalsContact O-N 3.12Å; F42-L214 HydrophobicContact CD1-CD2 4.17Å; F42-L214 HydrophobicContact CE1-CD2 3.56Å; F42-Y222 HydrophobicContact CZ-CG 4.47Å; F42-F227 HydrophobicContact CD2-CB 4.3Å; F42-F227 HydrophobicContact CD2-CD2 4.32Å; F42-F227 HydrophobicContact CE2-CB 3.63Å; F42-F227 HydrophobicContact CE2-CD2 4.11Å; F42-F227 HydrophobicContact CE2-CG 4.39Å; F42-F227 HydrophobicContact CZ-CB 4.43Å; F42-A230 HydrophobicContact CE1-CB 4.25Å; F42-A230 HydrophobicContact CZ-CB 3.98Å
43	I	73.4	Confident	67	Low	19 Å²	19	64.2 Å²	64.2	10%	0.097	33%	0.33	C	S	.	.	H	α-helix	trans	-58.8	-46.1	177	-66.4	169.3	0	0	0	110.2	R39 I40 K45 V46 F47 F149 L214 Y215	R39-I43 HydrophobicContact CG-CD1 4.26Å; R39-I43 WeakPolarHBondContact O-CG1 3.45Å; R39-I43 PolarHBondContact O-N 3.2Å; I40-I43 PolarHBondContact O-N 3.4Å; I43-K45 VanDerWaalsContact C-N 3.31Å; I43-K45 PolarHBondContact O-N 3.37Å; I43-V46 WeakPolarHBondContact O-CB 3.48Å; I43-V46 PolarHBondContact O-N 3.4Å; I43-F47 HydrophobicContact CG2-CD2 3.69Å; I43-F47 HydrophobicContact CG2-CE2 3.64Å; I43-F47 VanDerWaalsContact O-CD2 3.32Å; I43-F47 WeakPolarHBondContact O-CD2 3.3Å; I43-F47 PolarHBondContact O-N 3.37Å; I43-F149 HydrophobicContact CG2-CE1 4.18Å; I43-F149 HydrophobicContact CG2-CZ 3.76Å; I43-L214 HydrophobicContact CG1-CB 4.5Å; I43-Y215 HydrophobicContact CD1-CD2 4.12Å
44	L	76.2	Confident	69.2	Low	52 Å²	52	61.3 Å²	61.3	27%	0.272	30%	0.297	S	S	.	.	H	α-helix	trans	-59	-42.1	178.5	-169	68.9	0	0	0	112	I40 R41 F42 V46 F47 L48 L282	I40-L44 WeakPolarHBondContact O-CB 3.45Å; I40-L44 PolarHBondContact O-N 3.46Å; R41-L44 PolarHBondContact O-N 3.33Å; F42-L44 VanDerWaalsContact C-N 3.32Å; F42-L44 PolarHBondContact O-N 3.31Å; L44-V46 VanDerWaalsContact C-N 3.29Å; L44-V46 PolarHBondContact O-N 3Å; L44-F47 PolarHBondContact O-N 3.19Å; L44-L48 VanDerWaalsContact O-CB 3.25Å; L44-L48 WeakPolarHBondContact O-CB 3.49Å; L44-L48 PolarHBondContact O-N 2.74Å; L44-L282 HydrophobicContact CD1-CD1 4.3Å; L44-L282 HydrophobicContact CD1-CD2 3.6Å; L44-L282 HydrophobicContact CD1-CG 4.48Å; L44-L282 HydrophobicContact CG-CD2 4.44Å
45	K	74.7	Confident	71.3	Confident	98 Å²	98	53.7 Å²	53.7	43%	0.426	26%	0.259	S	S	.	.	H	α-helix	trans	-61	-39.6	175.2	-74.9	178.8	176.8	-169.4	0	111.5	R41 F42 I43 L48 T49 F227	R41-K45 VanDerWaalsContact O-CG 3.3Å; R41-K45 WeakPolarHBondContact O-CG 3.49Å; R41-K45 PolarHBondContact O-N 2.76Å; F42-K45 WeakPolarHBondContact O-CB 3.4Å; F42-K45 PolarHBondContact O-N 2.97Å; I43-K45 VanDerWaalsContact C-N 3.31Å; I43-K45 PolarHBondContact O-N 3.37Å; K45-L48 PolarHBondContact O-N 2.9Å; K45-T49 PolarHBondContact O-N 3.16Å; K45-T49 PolarHBondContact O-OG1 3.28Å; K45-T49 VanDerWaalsContact O-OG1 3.14Å; K45-F227 VanDerWaalsContact C-CE2 3.45Å; K45-F227 HydrophobicContact CB-CD2 4.07Å; K45-F227 HydrophobicContact CB-CE2 3.35Å; K45-F227 HydrophobicContact CB-CZ 3.81Å
46	V	74	Confident	72.5	Confident	0 Å²	0	51.6 Å²	51.6	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-66.9	-44.2	-179	168.6	0	0	0	0	110.2	F42 I43 L44 T49 N50 L214 F227 A230 H234	F42-V46 HydrophobicContact CE1-CG2 4.28Å; F42-V46 HydrophobicContact CZ-CG2 4.46Å; F42-V46 PolarHBondContact O-N 3.24Å; F42-V46 VanDerWaalsContact O-N 3.12Å; I43-V46 WeakPolarHBondContact O-CB 3.48Å; I43-V46 PolarHBondContact O-N 3.4Å; L44-V46 VanDerWaalsContact C-N 3.29Å; L44-V46 PolarHBondContact O-N 3Å; V46-T49 PolarHBondContact O-N 2.99Å; V46-T49 PolarHBondContact O-OG1 3.18Å; V46-N50 PolarHBondContact O-N 3.36Å; V46-N50 PolarHBondContact O-ND2 3.07Å; V46-N50 VanDerWaalsContact O-ND2 3.13Å; V46-L214 HydrophobicContact CG1-CD1 4.21Å; V46-L214 HydrophobicContact CG2-CD2 4.24Å; V46-F227 HydrophobicContact CB-CE2 4.35Å; V46-F227 HydrophobicContact CG2-CD2 3.7Å; V46-F227 HydrophobicContact CG2-CE2 3.62Å; V46-A230 HydrophobicContact CG2-CB 4.01Å; V46-H234 HydrophobicContact CG1-CB 4.32Å
47	F	78.8	Confident	73.3	Confident	40 Å²	40	48.4 Å²	48.4	18%	0.175	23%	0.231	C	C	.	.	H	α-helix	trans	-64.9	-40.5	174.2	-81.8	-74.4	0	0	0	112.6	I43 L44 T49 N50 I51 F149	I43-F47 HydrophobicContact CG2-CD2 3.69Å; I43-F47 HydrophobicContact CG2-CE2 3.64Å; I43-F47 VanDerWaalsContact O-CD2 3.32Å; I43-F47 WeakPolarHBondContact O-CD2 3.3Å; I43-F47 PolarHBondContact O-N 3.37Å; L44-F47 PolarHBondContact O-N 3.19Å; F47-T49 VanDerWaalsContact C-N 3.34Å; F47-T49 PolarHBondContact O-N 3.35Å; F47-N50 PolarHBondContact O-N 2.95Å; F47-N50 VanDerWaalsContact O-N 3.13Å; F47-I51 VanDerWaalsContact O-CG1 3.27Å; F47-I51 WeakPolarHBondContact O-CG1 3.41Å; F47-I51 PolarHBondContact O-N 3.35Å; F47-F149 AromaticContact CE2-CD1 3.83Å; F47-F149 HydrophobicContact CE2-CD1 3.83Å; F47-F149 HydrophobicContact CE2-CD2 4.11Å; F47-F149 AromaticContact CE2-CE1 3.43Å; F47-F149 HydrophobicContact CE2-CE1 3.43Å; F47-F149 VanDerWaalsContact CE2-CE1 3.43Å; F47-F149 AromaticContact CE2-CE2 3.78Å; F47-F149 HydrophobicContact CE2-CE2 3.78Å; F47-F149 HydrophobicContact CE2-CG 4.14Å; F47-F149 AromaticContact CE2-CZ 3.42Å; F47-F149 HydrophobicContact CE2-CZ 3.42Å; F47-F149 VanDerWaalsContact CE2-CZ 3.42Å; F47-F149 HydrophobicContact CZ-CB 4.21Å; F47-F149 AromaticContact CZ-CD1 3.52Å; F47-F149 HydrophobicContact CZ-CD1 3.52Å; F47-F149 AromaticContact CZ-CD2 3.61Å; F47-F149 HydrophobicContact CZ-CD2 3.61Å; F47-F149 AromaticContact CZ-CE1 3.65Å; F47-F149 HydrophobicContact CZ-CE1 3.65Å; F47-F149 AromaticContact CZ-CE2 3.78Å; F47-F149 HydrophobicContact CZ-CE2 3.78Å; F47-F149 AromaticContact CZ-CG 3.49Å; F47-F149 HydrophobicContact CZ-CG 3.49Å; F47-F149 VanDerWaalsContact CZ-CG 3.49Å; F47-F149 AromaticContact CZ-CZ 3.79Å; F47-F149 HydrophobicContact CZ-CZ 3.79Å
48	L	77.5	Confident	74	Confident	29 Å²	29	44.3 Å²	44.3	15%	0.152	21%	0.205	C	C	.	.	H	α-helix	trans	-60.1	-44.1	179.3	-179.3	68.7	0	0	0	111.8	L44 K45 N50 I51 L52 L279 L282 V283	L44-L48 VanDerWaalsContact O-CB 3.25Å; L44-L48 WeakPolarHBondContact O-CB 3.49Å; L44-L48 PolarHBondContact O-N 2.74Å; K45-L48 PolarHBondContact O-N 2.9Å; L48-N50 VanDerWaalsContact C-N 3.3Å; L48-N50 PolarHBondContact O-N 3.26Å; L48-I51 PolarHBondContact O-N 2.97Å; L48-L52 PolarHBondContact O-N 3.42Å; L48-L279 HydrophobicContact CD1-CD1 4.43Å; L48-L279 HydrophobicContact CD1-CG 4.06Å; L48-L282 HydrophobicContact CD1-CB 3.79Å; L48-L282 HydrophobicContact CD1-CD1 4.47Å; L48-V283 HydrophobicContact CD1-CG2 3.71Å; L48-V283 HydrophobicContact CD2-CG2 3.93Å; L48-V283 HydrophobicContact CG-CG2 4.32Å
49	T	73.8	Confident	74.6	Confident	32 Å²	32	40.8 Å²	40.8	20%	0.196	19%	0.19	C	C	.	.	H	α-helix	trans	-61.5	-39	175	41.9	0	0	0	0	112.3	K45 V46 F47 L52 Q53 Y111 F227 S231	K45-T49 PolarHBondContact O-N 3.16Å; K45-T49 PolarHBondContact O-OG1 3.28Å; K45-T49 VanDerWaalsContact O-OG1 3.14Å; V46-T49 PolarHBondContact O-N 2.99Å; V46-T49 PolarHBondContact O-OG1 3.18Å; F47-T49 VanDerWaalsContact C-N 3.34Å; F47-T49 PolarHBondContact O-N 3.35Å; T49-L52 PolarHBondContact O-N 3.5Å; T49-Q53 PolarHBondContact O-N 3.16Å; T49-Q53 VanDerWaalsContact O-N 3.09Å; T49-Y111 WeakPolarHBondContact CB-OH 3.22Å; T49-F227 HydrophobicContact CG2-CE1 4.34Å; T49-F227 HydrophobicContact CG2-CZ 3.73Å; T49-S231 WeakPolarHBondContact OG1-CB 3.28Å
50	N	76	Confident	74.8	Confident	11 Å²	11	41 Å²	41	6%	0.059	20%	0.195	C	C	.	.	H	α-helix	trans	-69.7	-41	178.7	-63	-23.8	0	0	0	112	V46 F47 L48 L52 Q53 I54 S231 H234	V46-N50 PolarHBondContact O-N 3.36Å; V46-N50 PolarHBondContact O-ND2 3.07Å; V46-N50 VanDerWaalsContact O-ND2 3.13Å; F47-N50 PolarHBondContact O-N 2.95Å; F47-N50 VanDerWaalsContact O-N 3.13Å; L48-N50 VanDerWaalsContact C-N 3.3Å; L48-N50 PolarHBondContact O-N 3.26Å; N50-L52 VanDerWaalsContact C-N 3.31Å; N50-L52 PolarHBondContact O-N 3.04Å; N50-Q53 WeakPolarHBondContact O-CB 3.43Å; N50-Q53 PolarHBondContact O-N 3.04Å; N50-I54 VanDerWaalsContact O-CG1 3.29Å; N50-I54 WeakPolarHBondContact O-CG1 3.43Å; N50-I54 PolarHBondContact O-N 2.83Å; N50-S231 PolarHBondContact OD1-O 3.4Å; N50-H234 WeakPolarHBondContact ND2-CB 3.39Å
51	I	78	Confident	74.8	Confident	33 Å²	33	37 Å²	37	17%	0.169	17%	0.174	C	C	.	.	H	α-helix	trans	-62.1	-42.3	176.4	-66.6	167.7	0	0	0	110.1	F47 L48 Q53 I54 F55 I275 V278 L279 L282	F47-I51 VanDerWaalsContact O-CG1 3.27Å; F47-I51 WeakPolarHBondContact O-CG1 3.41Å; F47-I51 PolarHBondContact O-N 3.35Å; L48-I51 PolarHBondContact O-N 2.97Å; I51-Q53 VanDerWaalsContact C-N 3.27Å; I51-Q53 PolarHBondContact O-N 3.42Å; I51-I54 PolarHBondContact O-N 2.86Å; I51-F55 WeakPolarHBondContact O-CB 3.47Å; I51-F55 PolarHBondContact O-N 2.86Å; I51-I275 HydrophobicContact CG2-CG2 3.73Å; I51-V278 HydrophobicContact CD1-CG1 4.2Å; I51-L279 HydrophobicContact CB-CD1 4.31Å; I51-L279 HydrophobicContact CG2-CB 3.9Å; I51-L279 HydrophobicContact CG2-CD1 3.87Å; I51-L279 HydrophobicContact CG2-CG 4.46Å; I51-L282 HydrophobicContact CD1-CD1 3.86Å
52	L	77.6	Confident	74.8	Confident	94 Å²	94	30.3 Å²	30.3	49%	0.492	15%	0.149	S	C	.	.	H	α-helix	trans	-59	-42.3	175.9	-173.8	60.8	0	0	0	111.6	L48 T49 N50 F55 L56 L279	L48-L52 PolarHBondContact O-N 3.42Å; T49-L52 PolarHBondContact O-N 3.5Å; N50-L52 VanDerWaalsContact C-N 3.31Å; N50-L52 PolarHBondContact O-N 3.04Å; L52-F55 WeakPolarHBondContact O-CB 3.43Å; L52-F55 PolarHBondContact O-N 3.08Å; L52-L56 WeakPolarHBondContact O-CB 2.9Å; L52-L56 PolarHBondContact O-N 2.78Å; L52-L279 HydrophobicContact CB-CD1 3.53Å; L52-L279 HydrophobicContact CD1-CD1 3.7Å; L52-L279 HydrophobicContact CD1-CD2 4.25Å; L52-L279 HydrophobicContact CG-CD1 4.2Å; L52-L279 VanDerWaalsContact N-CD1 3.3Å
53	Q	71.9	Confident	74.8	Confident	6 Å²	6	31.9 Å²	31.9	3%	0.028	16%	0.158	C	C	.	.	H	α-helix	trans	-66	-45.8	178.2	-177.4	83	-24.8	0	0	112.6	T49 N50 I51 F55 L56 S57 T115 L235	T49-Q53 PolarHBondContact O-N 3.16Å; T49-Q53 VanDerWaalsContact O-N 3.09Å; N50-Q53 WeakPolarHBondContact O-CB 3.43Å; N50-Q53 PolarHBondContact O-N 3.04Å; I51-Q53 VanDerWaalsContact C-N 3.27Å; I51-Q53 PolarHBondContact O-N 3.42Å; Q53-F55 VanDerWaalsContact C-N 3.26Å; Q53-F55 PolarHBondContact O-N 3.16Å; Q53-L56 PolarHBondContact O-N 2.86Å; Q53-S57 WeakPolarHBondContact O-CB 3.28Å; Q53-S57 PolarHBondContact O-N 3.26Å; Q53-S57 PolarHBondContact O-OG 3.38Å; Q53-T115 PolarHBondContact NE2-O 3.16Å; Q53-T115 PolarHBondContact OE1-O 3.19Å; Q53-L235 HydrophobicContact CB-CD1 4.21Å; Q53-L235 HydrophobicContact CG-CD1 3.5Å; Q53-L235 VanDerWaalsContact CG-CD1 3.5Å; Q53-L235 HydrophobicContact CG-CD2 4.26Å
54	I	76.6	Confident	74.4	Confident	11 Å²	11	32.7 Å²	32.7	6%	0.056	16%	0.164	C	C	.	.	H	α-helix	trans	-57.1	-47.7	176.4	-65	163.6	0	0	0	109	N50 I51 L56 S57 I58 W138 I142 L238 I275	N50-I54 VanDerWaalsContact O-CG1 3.29Å; N50-I54 WeakPolarHBondContact O-CG1 3.43Å; N50-I54 PolarHBondContact O-N 2.83Å; I51-I54 PolarHBondContact O-N 2.86Å; I54-L56 PolarHBondContact O-N 3.5Å; I54-S57 PolarHBondContact O-N 2.98Å; I54-I58 HydrophobicContact CG2-CD1 3.62Å; I54-I58 HydrophobicContact CG2-CG1 4.26Å; I54-I58 VanDerWaalsContact O-CG1 3.32Å; I54-I58 WeakPolarHBondContact O-CG1 3.12Å; I54-I58 PolarHBondContact O-N 2.73Å; I54-W138 HydrophobicContact CB-CZ3 4.47Å; I54-W138 HydrophobicContact CG1-CE3 4.41Å; I54-W138 HydrophobicContact CG1-CH2 4.34Å; I54-W138 HydrophobicContact CG1-CZ3 3.84Å; I54-W138 HydrophobicContact CG2-CD2 4.36Å; I54-W138 HydrophobicContact CG2-CE3 3.96Å; I54-W138 HydrophobicContact CG2-CZ3 4.11Å; I54-I142 HydrophobicContact CD1-CD1 4.43Å; I54-I142 HydrophobicContact CD1-CG1 4.07Å; I54-I142 HydrophobicContact CG2-CD1 4.2Å; I54-L238 HydrophobicContact CD1-CD1 4.41Å; I54-L238 HydrophobicContact CD1-CD2 3.56Å; I54-L238 HydrophobicContact CG1-CD2 3.43Å; I54-L238 VanDerWaalsContact CG1-CD2 3.43Å; I54-I275 HydrophobicContact CG2-CD1 3.8Å
55	F	78.7	Confident	73.9	Confident	30 Å²	30	31.2 Å²	31.2	13%	0.132	16%	0.155	C	C	.	.	H	α-helix	trans	-54.8	-52.6	176.7	178	-97.5	0	0	0	111.3	I51 L52 Q53 S57 I58 F59 L272 I275 L276 F377	I51-F55 WeakPolarHBondContact O-CB 3.47Å; I51-F55 PolarHBondContact O-N 2.86Å; L52-F55 WeakPolarHBondContact O-CB 3.43Å; L52-F55 PolarHBondContact O-N 3.08Å; Q53-F55 VanDerWaalsContact C-N 3.26Å; Q53-F55 PolarHBondContact O-N 3.16Å; F55-S57 VanDerWaalsContact C-N 3.3Å; F55-S57 PolarHBondContact O-N 3.26Å; F55-I58 PolarHBondContact O-N 3.33Å; F55-F59 WeakPolarHBondContact O-CB 3.43Å; F55-F59 PolarHBondContact O-N 3.09Å; F55-L272 HydrophobicContact CD2-CD2 3.79Å; F55-L272 HydrophobicContact CE2-CB 4.27Å; F55-L272 HydrophobicContact CE2-CD2 3.77Å; F55-I275 HydrophobicContact CB-CG2 3.74Å; F55-I275 HydrophobicContact CD2-CG2 4.24Å; F55-I275 HydrophobicContact CG-CG2 4.47Å; F55-L276 HydrophobicContact CD2-CB 4.12Å; F55-L276 HydrophobicContact CE2-CB 3.74Å; F55-L276 HydrophobicContact CE2-CD1 4.14Å; F55-L276 HydrophobicContact CE2-CD2 4.39Å; F55-L276 HydrophobicContact CE2-CG 4.3Å; F55-L276 HydrophobicContact CZ-CB 4.46Å; F55-L276 HydrophobicContact CZ-CD1 4.08Å; F55-L276 HydrophobicContact CZ-CD2 4.42Å; F55-F377 HydrophobicContact CE2-CE1 4.43Å; F55-F377 AromaticContact CE2-CZ 3.75Å; F55-F377 HydrophobicContact CE2-CZ 3.75Å; F55-F377 HydrophobicContact CZ-CE1 4.35Å; F55-F377 AromaticContact CZ-CZ 3.87Å; F55-F377 HydrophobicContact CZ-CZ 3.87Å
56	L	76.4	Confident	73.3	Confident	39 Å²	39	27.2 Å²	27.2	20%	0.204	14%	0.14	C	C	.	.	H	α-helix	trans	-60.6	-40.2	179.8	-173.2	68.1	0	0	0	111.8	L52 Q53 I54 F59 M60 Y116	L52-L56 WeakPolarHBondContact O-CB 2.9Å; L52-L56 PolarHBondContact O-N 2.78Å; Q53-L56 PolarHBondContact O-N 2.86Å; I54-L56 PolarHBondContact O-N 3.5Å; L56-F59 PolarHBondContact O-N 3.09Å; L56-M60 HydrophobicContact CD1-CG 4.42Å; L56-M60 HydrophobicContact CG-CG 4.4Å; L56-M60 WeakPolarHBondContact O-CB 3.47Å; L56-M60 VanDerWaalsContact O-CG 3.23Å; L56-M60 WeakPolarHBondContact O-CG 3.23Å; L56-M60 PolarHBondContact O-N 2.94Å; L56-Y116 HydrophobicContact CD2-CD1 4.3Å; L56-Y116 HydrophobicContact CD2-CE1 3.99Å
57	S	73.6	Confident	72.8	Confident	0 Å²	0	30.5 Å²	30.5	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-69.2	-44	-178.5	-54.2	0	0	0	0	111.9	Q53 I54 F55 F59 T61	Q53-S57 WeakPolarHBondContact O-CB 3.28Å; Q53-S57 PolarHBondContact O-N 3.26Å; Q53-S57 PolarHBondContact O-OG 3.38Å; I54-S57 PolarHBondContact O-N 2.98Å; F55-S57 VanDerWaalsContact C-N 3.3Å; F55-S57 PolarHBondContact O-N 3.26Å; S57-F59 VanDerWaalsContact C-N 3.33Å; S57-T61 VanDerWaalsContact O-CB 3.31Å; S57-T61 WeakPolarHBondContact O-CB 3.33Å; S57-T61 PolarHBondContact O-N 3.17Å; S57-T61 PolarHBondContact O-OG1 3.32Å
58	I	75.2	Confident	71.5	Confident	0 Å²	0	33.3 Å²	33.3	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-64.5	-42	174.7	-65.8	173.9	0	0	0	109.9	I54 F55 T61 A62 F135 W138 I271 L272 I275	I54-I58 HydrophobicContact CG2-CD1 3.62Å; I54-I58 HydrophobicContact CG2-CG1 4.26Å; I54-I58 VanDerWaalsContact O-CG1 3.32Å; I54-I58 WeakPolarHBondContact O-CG1 3.12Å; I54-I58 PolarHBondContact O-N 2.73Å; F55-I58 PolarHBondContact O-N 3.33Å; I58-T61 PolarHBondContact O-N 3.37Å; I58-A62 WeakPolarHBondContact O-CB 3.32Å; I58-A62 PolarHBondContact O-N 3.04Å; I58-F135 HydrophobicContact CG2-CE1 4.12Å; I58-W138 HydrophobicContact CD1-CB 4.4Å; I58-W138 HydrophobicContact CD1-CD2 4.41Å; I58-W138 HydrophobicContact CD1-CG 4.06Å; I58-W138 HydrophobicContact CG1-CD2 4.36Å; I58-W138 HydrophobicContact CG1-CG 4.13Å; I58-I271 HydrophobicContact CD1-CG2 3.86Å; I58-L272 HydrophobicContact CB-CD2 3.86Å; I58-L272 HydrophobicContact CG2-CD1 4.44Å; I58-L272 HydrophobicContact CG2-CD2 3.52Å; I58-L272 HydrophobicContact CG2-CG 3.82Å; I58-I275 HydrophobicContact CD1-CD1 3.61Å
59	F	76.9	Confident	70.4	Confident	47 Å²	47	38.6 Å²	38.6	21%	0.206	20%	0.201	C	C	.	.	H	α-helix	trans	-63.2	-49.3	178.7	-178.6	-108.1	0	0	0	112.2	F55 L56 S57 T61 A62 L63 L272 F377 M380	F55-F59 WeakPolarHBondContact O-CB 3.43Å; F55-F59 PolarHBondContact O-N 3.09Å; L56-F59 PolarHBondContact O-N 3.09Å; S57-F59 VanDerWaalsContact C-N 3.33Å; F59-T61 VanDerWaalsContact C-N 3.31Å; F59-T61 PolarHBondContact O-N 3.38Å; F59-A62 PolarHBondContact O-N 3.21Å; F59-L63 HydrophobicContact CD1-CD1 3.87Å; F59-L63 HydrophobicContact CD1-CG 4.48Å; F59-L63 HydrophobicContact CE1-CD1 3.39Å; F59-L63 HydrophobicContact CE1-CG 4.15Å; F59-L63 HydrophobicContact CE2-CG 4.49Å; F59-L63 HydrophobicContact CZ-CD1 3.78Å; F59-L63 HydrophobicContact CZ-CD2 4.32Å; F59-L63 HydrophobicContact CZ-CG 4.14Å; F59-L63 WeakPolarHBondContact O-CG 3.44Å; F59-L63 PolarHBondContact O-N 2.99Å; F59-L272 HydrophobicContact CB-CD2 4.23Å; F59-L272 HydrophobicContact CD2-CD1 4.45Å; F59-F377 HydrophobicContact CD2-CE1 4.44Å; F59-M380 HydrophobicContact CE2-SD 3.7Å; F59-M380 HydrophobicContact CZ-SD 4.12Å
60	M	72.2	Confident	69.4	Low	75 Å²	75	38.5 Å²	38.5	37%	0.369	20%	0.2	S	C	.	.	H	α-helix	trans	-62.1	-39.6	176.2	-71.8	-61.6	-130.2	0	0	111.9	L56 L63 V64	L56-M60 HydrophobicContact CD1-CG 4.42Å; L56-M60 HydrophobicContact CG-CG 4.4Å; L56-M60 WeakPolarHBondContact O-CB 3.47Å; L56-M60 VanDerWaalsContact O-CG 3.23Å; L56-M60 WeakPolarHBondContact O-CG 3.23Å; L56-M60 PolarHBondContact O-N 2.94Å; M60-L63 PolarHBondContact O-N 3.41Å; M60-L63 HydrophobicContact SD-CD1 4.17Å; M60-V64 WeakPolarHBondContact O-CG2 3.4Å; M60-V64 PolarHBondContact O-N 3.11Å
61	T	70.4	Confident	68.2	Low	0 Å²	0	44 Å²	44	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-62	-46.6	175.4	-55.5	0	0	0	0	110.9	S57 I58 F59 L63 V64 Y65 T123 I134	S57-T61 VanDerWaalsContact O-CB 3.31Å; S57-T61 WeakPolarHBondContact O-CB 3.33Å; S57-T61 PolarHBondContact O-N 3.17Å; S57-T61 PolarHBondContact O-OG1 3.32Å; I58-T61 PolarHBondContact O-N 3.37Å; F59-T61 VanDerWaalsContact C-N 3.31Å; F59-T61 PolarHBondContact O-N 3.38Å; T61-L63 VanDerWaalsContact C-N 3.31Å; T61-L63 PolarHBondContact O-N 2.84Å; T61-V64 PolarHBondContact O-N 3.35Å; T61-Y65 HydrophobicContact CG2-CD2 3.89Å; T61-Y65 HydrophobicContact CG2-CE2 3.76Å; T61-Y65 VanDerWaalsContact O-CD2 3.26Å; T61-Y65 WeakPolarHBondContact O-CD2 3.27Å; T61-Y65 PolarHBondContact O-N 2.9Å; T61-T123 PolarHBondContact N-OG1 3.18Å; T61-T123 WeakPolarHBondContact OG1-CA 3.34Å; T61-T123 PolarHBondContact OG1-OG1 2.85Å; T61-I134 HydrophobicContact CG2-CG2 4.3Å
62	A	67.6	Low	66.8	Low	0 Å²	0	45.3 Å²	45.3	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-60.3	-39.7	175.4	0	0	0	0	0	112.4	I58 F59 A66 I268 F381	I58-A62 WeakPolarHBondContact O-CB 3.32Å; I58-A62 PolarHBondContact O-N 3.04Å; F59-A62 PolarHBondContact O-N 3.21Å; A62-A66 WeakPolarHBondContact O-CB 3.24Å; A62-A66 PolarHBondContact O-N 3.26Å; A62-I268 HydrophobicContact CB-CG2 3.95Å; A62-F381 HydrophobicContact CB-CE1 3.73Å; A62-F381 HydrophobicContact CB-CZ 3.76Å
63	L	70.8	Confident	65.7	Low	53 Å²	53	43.1 Å²	43.1	28%	0.277	23%	0.229	S	C	.	.	H	α-helix	trans	-64.7	-40.2	174.6	-74.1	177.1	0	0	0	112.7	F59 M60 T61 A66 T67	F59-L63 HydrophobicContact CD1-CD1 3.87Å; F59-L63 HydrophobicContact CD1-CG 4.48Å; F59-L63 HydrophobicContact CE1-CD1 3.39Å; F59-L63 HydrophobicContact CE1-CG 4.15Å; F59-L63 HydrophobicContact CE2-CG 4.49Å; F59-L63 HydrophobicContact CZ-CD1 3.78Å; F59-L63 HydrophobicContact CZ-CD2 4.32Å; F59-L63 HydrophobicContact CZ-CG 4.14Å; F59-L63 WeakPolarHBondContact O-CG 3.44Å; F59-L63 PolarHBondContact O-N 2.99Å; M60-L63 PolarHBondContact O-N 3.41Å; M60-L63 HydrophobicContact SD-CD1 4.17Å; T61-L63 VanDerWaalsContact C-N 3.31Å; T61-L63 PolarHBondContact O-N 2.84Å; L63-A66 WeakPolarHBondContact O-CA 3.43Å; L63-A66 VanDerWaalsContact O-CB 3.24Å; L63-A66 WeakPolarHBondContact O-CB 3.4Å; L63-A66 PolarHBondContact O-N 3.46Å; L63-A66 VanDerWaalsContact O-N 3.09Å; L63-T67 PolarHBondContact O-N 3.47Å
64	V	66.6	Low	64.8	Low	37 Å²	37	47.7 Å²	47.7	22%	0.224	25%	0.253	C	S	.	.	H	α-helix	trans	-65.7	-44.1	177.7	170.2	0	0	0	0	111	M60 T61 A66 T67 V70 L73 T123 I127	M60-V64 WeakPolarHBondContact O-CG2 3.4Å; M60-V64 PolarHBondContact O-N 3.11Å; T61-V64 PolarHBondContact O-N 3.35Å; V64-A66 PolarHBondContact O-N 2.95Å; V64-T67 PolarHBondContact O-N 3.31Å; V64-T67 VanDerWaalsContact O-N 3.09Å; V64-T67 VanDerWaalsContact O-O 3.08Å; V64-T67 PolarHBondContact O-OG1 2.91Å; V64-V70 HydrophobicContact CG1-CG2 4.45Å; V64-L73 HydrophobicContact CG1-CD1 4.34Å; V64-T123 HydrophobicContact CB-CG2 3.87Å; V64-T123 HydrophobicContact CG1-CG2 4.34Å; V64-T123 HydrophobicContact CG2-CG2 3.54Å; V64-I127 HydrophobicContact CG1-CD1 3.76Å; V64-I127 HydrophobicContact CG1-CG1 4.11Å
65	Y	64.2	Low	63.8	Low	21 Å²	21	55.7 Å²	55.7	8%	0.082	29%	0.288	C	S	.	.	H	α-helix	trans	-63.1	-23.5	171.6	-81.6	-74.5	0	0	0	113.2	T61 T67 S126 I127 V129 I134 L386	T61-Y65 HydrophobicContact CG2-CD2 3.89Å; T61-Y65 HydrophobicContact CG2-CE2 3.76Å; T61-Y65 VanDerWaalsContact O-CD2 3.26Å; T61-Y65 WeakPolarHBondContact O-CD2 3.27Å; T61-Y65 PolarHBondContact O-N 2.9Å; Y65-T67 VanDerWaalsContact C-N 3.27Å; Y65-T67 PolarHBondContact O-N 3.34Å; Y65-S126 PolarHBondContact OH-O 2.89Å; Y65-I127 VanDerWaalsContact OH-CA 3.26Å; Y65-I127 WeakPolarHBondContact OH-CA 3.39Å; Y65-I127 PolarHBondContact OH-O 3.32Å; Y65-V129 PolarHBondContact OH-O 3.11Å; Y65-I134 HydrophobicContact CE2-CD1 3.65Å; Y65-I134 VanDerWaalsContact OH-CD1 3.23Å; Y65-I134 WeakPolarHBondContact OH-CD1 3.35Å; Y65-L386 WeakPolarHBondContact O-CD2 3.44Å
66	A	63.1	Low	62.9	Low	13 Å²	13	58.8 Å²	58.8	11%	0.107	30%	0.302	C	S	.	.	H	α-helix	trans	-74.2	-17.4	175.4	0	0	0	0	0	113.9	A62 L63 V64 W325 I384	A62-A66 WeakPolarHBondContact O-CB 3.24Å; A62-A66 PolarHBondContact O-N 3.26Å; L63-A66 WeakPolarHBondContact O-CA 3.43Å; L63-A66 VanDerWaalsContact O-CB 3.24Å; L63-A66 WeakPolarHBondContact O-CB 3.4Å; L63-A66 PolarHBondContact O-N 3.46Å; L63-A66 VanDerWaalsContact O-N 3.09Å; V64-A66 PolarHBondContact O-N 2.95Å; A66-W325 HydrophobicContact CB-CH2 4.24Å; A66-I384 HydrophobicContact CB-CD1 3.31Å; A66-I384 HydrophobicContact CB-CG1 3.94Å; A66-I384 HydrophobicContact CB-CG2 4.1Å
67	T	62.3	Low	62	Low	69 Å²	69	61.3 Å²	61.3	42%	0.423	31%	0.31	S	S	.	.	S	Bend	trans	-104.7	130.6	-179	59.9	0	0	0	0	110.3	L63 V64 Y65 Q69	L63-T67 PolarHBondContact O-N 3.47Å; V64-T67 PolarHBondContact O-N 3.31Å; V64-T67 VanDerWaalsContact O-N 3.09Å; V64-T67 VanDerWaalsContact O-O 3.08Å; V64-T67 PolarHBondContact O-OG1 2.91Å; Y65-T67 VanDerWaalsContact C-N 3.27Å; Y65-T67 PolarHBondContact O-N 3.34Å; T67-Q69 PolarHBondContact O-N 2.94Å
68	D	53	Low	61.2	Low	100 Å²	100	70.5 Å²	70.5	54%	0.535	35%	0.345	S	S	.	.	T	Hydrogen-bonded Turn	trans	-59.3	2	-179.2	-64.2	-5.7	0	0	0	115.3	V70 P387	D68-V70 VanDerWaalsContact C-N 3.28Å; D68-V70 PolarHBondContact O-N 3.14Å; D68-P387 HydrophobicContact CB-CG 4.31Å; D68-P387 WeakPolarHBondContact OD1-CD 3.44Å
69	Q	54.6	Low	60.3	Low	140 Å²	140	74.2 Å²	74.2	65%	0.654	36%	0.364	S	S	*	.	T	Hydrogen-bonded Turn	trans	-79.3	-3	-177.1	-65.5	-165.6	-6.6	0	0	114.6	T67 I71 S72	T67-Q69 PolarHBondContact O-N 2.94Å; Q69-I71 PolarHBondContact O-N 3.39Å; Q69-I71 VanDerWaalsContact O-N 3.16Å; Q69-S72 PolarHBondContact O-N 3.24Å; Q69-S72 PolarHBondContact O-OG 2.86Å
70	V	52.8	Low	59.3	Low	29 Å²	29	72.2 Å²	72.2	18%	0.176	36%	0.356	C	S	.	.	H	α-helix	trans	-54	-37.4	-179.8	-177.3	0	0	0	0	112.1	V64 D68 S72 L73 D74 I127	V64-V70 HydrophobicContact CG1-CG2 4.45Å; D68-V70 VanDerWaalsContact C-N 3.28Å; D68-V70 PolarHBondContact O-N 3.14Å; V70-S72 PolarHBondContact O-N 3.46Å; V70-S72 VanDerWaalsContact O-N 3.16Å; V70-L73 PolarHBondContact O-N 3.31Å; V70-L73 VanDerWaalsContact O-N 3.08Å; V70-D74 PolarHBondContact O-N 2.85Å; V70-I127 HydrophobicContact CG1-CG2 3.82Å
71	I	49.4	Very low	58.6	Low	126 Å²	126	70.6 Å²	70.6	65%	0.646	35%	0.348	S	S	*	.	H	α-helix	trans	-62.6	-26.5	-178.3	-59.1	170.2	0	0	0	112.6	Q69	Q69-I71 PolarHBondContact O-N 3.39Å; Q69-I71 VanDerWaalsContact O-N 3.16Å
72	S	50	Low	58.1	Low	61 Å²	61	75.3 Å²	75.3	43%	0.427	37%	0.373	S	S	.	.	H	α-helix	trans	-80.7	-27.6	178.2	70.9	0	0	0	0	113.2	Q69 V70 H76	Q69-S72 PolarHBondContact O-N 3.24Å; Q69-S72 PolarHBondContact O-OG 2.86Å; V70-S72 PolarHBondContact O-N 3.46Å; V70-S72 VanDerWaalsContact O-N 3.16Å; S72-H76 PolarHBondContact O-CE1 2.98Å; S72-H76 PolarHBondContact O-ND1 2.92Å
73	L	53.9	Low	57.5	Low	48 Å²	48	78 Å²	78	25%	0.251	39%	0.387	S	S	.	.	H	α-helix	trans	-80.9	-31.2	-173.9	-70.8	170.7	0	0	0	112.5	V64 V70 K75 H76 F124 I127	V64-L73 HydrophobicContact CG1-CD1 4.34Å; V70-L73 PolarHBondContact O-N 3.31Å; V70-L73 VanDerWaalsContact O-N 3.08Å; L73-K75 PolarHBondContact O-N 3.47Å; L73-K75 VanDerWaalsContact O-N 3.16Å; L73-H76 WeakPolarHBondContact O-CA 3.48Å; L73-H76 WeakPolarHBondContact O-CB 3.41Å; L73-H76 PolarHBondContact O-N 3Å; L73-F124 HydrophobicContact CD1-CE1 4.05Å; L73-F124 HydrophobicContact CD2-CE1 3.54Å; L73-F124 HydrophobicContact CD2-CZ 4.22Å; L73-F124 HydrophobicContact CG-CE1 4.23Å; L73-I127 HydrophobicContact CB-CD1 4.31Å; L73-I127 HydrophobicContact CD1-CD1 3.8Å
74	D	53.7	Low	56.9	Low	103 Å²	103	76.7 Å²	76.7	55%	0.551	38%	0.382	S	S	*	.	G	3₁₀ helix	trans	-57.9	-30.8	178.3	-153.1	18.9	0	0	0	112.3	V70 H76	V70-D74 PolarHBondContact O-N 2.85Å; D74-H76 PolarHBondContact O-N 3.23Å; D74-H76 VanDerWaalsContact O-N 3.1Å
75	K	53.9	Low	56.7	Low	178 Å²	178	79.1 Å²	79.1	77%	0.774	40%	0.397	S	S	*	.	G	3₁₀ helix	trans	-67	-10.2	174.9	-65.8	-176.6	-179.7	178.7	0	114.3	L73	L73-K75 PolarHBondContact O-N 3.47Å; L73-K75 VanDerWaalsContact O-N 3.16Å
76	H	60.2	Low	56.6	Low	95 Å²	95	81.8 Å²	81.8	44%	0.44	41%	0.411	S	S	.	.	G	3₁₀ helix	trans	-117.4	28.8	-170.6	-61.2	69	0	0	0	112.3	S72 L73 D74 W78 I79	S72-H76 PolarHBondContact O-CE1 2.98Å; S72-H76 PolarHBondContact O-ND1 2.92Å; L73-H76 WeakPolarHBondContact O-CA 3.48Å; L73-H76 WeakPolarHBondContact O-CB 3.41Å; L73-H76 PolarHBondContact O-N 3Å; D74-H76 PolarHBondContact O-N 3.23Å; D74-H76 VanDerWaalsContact O-N 3.1Å; H76-W78 PolarHBondContact O-N 3.35Å; H76-I79 HydrophobicContact CB-CB 4.36Å; H76-I79 HydrophobicContact CB-CD1 3.87Å; H76-I79 HydrophobicContact CB-CG1 4.03Å; H76-I79 WeakPolarHBondContact O-CA 3.4Å; H76-I79 VanDerWaalsContact O-CB 3.28Å; H76-I79 WeakPolarHBondContact O-CB 3.46Å; H76-I79 PolarHBondContact O-N 2.81Å
77	Y	58	Low	56.4	Low	93 Å²	93	81.5 Å²	81.5	37%	0.365	41%	0.408	S	S	.	.	H	α-helix	trans	-46	-39	177	-178.8	-107.9	0	0	0	114	I79 A80 I81 N128 W184	Y77-I79 VanDerWaalsContact C-N 3.27Å; Y77-I79 PolarHBondContact O-N 3.29Å; Y77-A80 WeakPolarHBondContact O-CB 3.43Å; Y77-A80 PolarHBondContact O-N 3.05Å; Y77-I81 HydrophobicContact CD1-CD1 4Å; Y77-I81 HydrophobicContact CE1-CD1 3.55Å; Y77-I81 HydrophobicContact CE1-CG1 4.16Å; Y77-I81 PolarHBondContact O-N 2.91Å; Y77-N128 WeakPolarHBondContact CD2-ND2 3.48Å; Y77-W184 AromaticContact CE1-CH2 3.94Å; Y77-W184 HydrophobicContact CE1-CH2 3.94Å; Y77-W184 HydrophobicContact CE1-CZ2 4.14Å; Y77-W184 WeakPolarHBondContact OH-CH2 3.36Å; Y77-W184 VanDerWaalsContact OH-CZ2 3.26Å; Y77-W184 WeakPolarHBondContact OH-CZ2 3.42Å
78	W	55.7	Low	56.2	Low	192 Å²	192	81.6 Å²	81.6	73%	0.727	41%	0.405	S	S	*	.	H	α-helix	trans	-60.6	-31.6	176.3	-67.4	104.6	0	0	0	113.9	H76 A80 I81 I82	H76-W78 PolarHBondContact O-N 3.35Å; W78-A80 VanDerWaalsContact C-N 3.32Å; W78-A80 PolarHBondContact O-N 3.1Å; W78-I81 HydrophobicContact CE3-CD1 3.91Å; W78-I81 HydrophobicContact CZ3-CD1 4.11Å; W78-I81 PolarHBondContact O-N 3.2Å; W78-I82 VanDerWaalsContact O-CG1 3.3Å; W78-I82 WeakPolarHBondContact O-CG1 3.34Å; W78-I82 PolarHBondContact O-N 2.97Å
79	I	57.9	Low	56.7	Low	79 Å²	79	78.7 Å²	78.7	41%	0.405	40%	0.399	S	S	.	.	H	α-helix	trans	-64.7	-38.6	175.2	-61	-170.3	0	0	0	110.2	H76 Y77 I81 I82 L83	H76-I79 HydrophobicContact CB-CB 4.36Å; H76-I79 HydrophobicContact CB-CD1 3.87Å; H76-I79 HydrophobicContact CB-CG1 4.03Å; H76-I79 WeakPolarHBondContact O-CA 3.4Å; H76-I79 VanDerWaalsContact O-CB 3.28Å; H76-I79 WeakPolarHBondContact O-CB 3.46Å; H76-I79 PolarHBondContact O-N 2.81Å; Y77-I79 VanDerWaalsContact C-N 3.27Å; Y77-I79 PolarHBondContact O-N 3.29Å; I79-I81 VanDerWaalsContact C-N 3.35Å; I79-I81 PolarHBondContact O-N 3.46Å; I79-I82 PolarHBondContact O-N 3.39Å; I79-L83 HydrophobicContact CG2-CD1 3.79Å; I79-L83 HydrophobicContact CG2-CG 4.13Å; I79-L83 WeakPolarHBondContact O-CB 3.41Å; I79-L83 VanDerWaalsContact O-CG 3.31Å; I79-L83 WeakPolarHBondContact O-CG 3.3Å; I79-L83 PolarHBondContact O-N 3.4Å
80	A	55	Low	56.8	Low	5 Å²	5	74.8 Å²	74.8	4%	0.041	38%	0.381	C	S	.	.	H	α-helix	trans	-64	-40.9	177.3	0	0	0	0	0	111.6	Y77 W78 L83 S84 F124	Y77-A80 WeakPolarHBondContact O-CB 3.43Å; Y77-A80 PolarHBondContact O-N 3.05Å; W78-A80 VanDerWaalsContact C-N 3.32Å; W78-A80 PolarHBondContact O-N 3.1Å; A80-L83 PolarHBondContact O-N 2.84Å; A80-S84 WeakPolarHBondContact O-CB 3.45Å; A80-S84 PolarHBondContact O-N 2.89Å; A80-S84 PolarHBondContact O-OG 3.16Å; A80-F124 HydrophobicContact CB-CB 4.3Å
81	I	57.7	Low	57.1	Low	41 Å²	41	74.5 Å²	74.5	21%	0.21	38%	0.379	C	S	.	.	H	α-helix	trans	-62.4	-49.2	173.9	-60.3	173.5	0	0	0	110.1	Y77 W78 I79 L83 S84 V85 W184	Y77-I81 HydrophobicContact CD1-CD1 4Å; Y77-I81 HydrophobicContact CE1-CD1 3.55Å; Y77-I81 HydrophobicContact CE1-CG1 4.16Å; Y77-I81 PolarHBondContact O-N 2.91Å; W78-I81 HydrophobicContact CE3-CD1 3.91Å; W78-I81 HydrophobicContact CZ3-CD1 4.11Å; W78-I81 PolarHBondContact O-N 3.2Å; I79-I81 VanDerWaalsContact C-N 3.35Å; I79-I81 PolarHBondContact O-N 3.46Å; I81-L83 VanDerWaalsContact C-N 3.35Å; I81-L83 PolarHBondContact O-N 2.91Å; I81-S84 PolarHBondContact O-N 3.34Å; I81-S84 PolarHBondContact O-OG 3.18Å; I81-V85 HydrophobicContact CG2-CG2 4.44Å; I81-V85 WeakPolarHBondContact O-CG2 3.26Å; I81-V85 PolarHBondContact O-N 3.44Å; I81-W184 HydrophobicContact CD1-CH2 3.77Å; I81-W184 HydrophobicContact CD1-CZ3 4.07Å
82	I	59.4	Low	57.7	Low	99 Å²	99	73.2 Å²	73.2	51%	0.508	37%	0.372	S	S	.	.	H	α-helix	trans	-59	-46.7	178.9	-68.6	166.3	0	0	0	111	W78 I79 S84 V85 I86	W78-I82 VanDerWaalsContact O-CG1 3.3Å; W78-I82 WeakPolarHBondContact O-CG1 3.34Å; W78-I82 PolarHBondContact O-N 2.97Å; I79-I82 PolarHBondContact O-N 3.39Å; I82-S84 VanDerWaalsContact C-N 3.34Å; I82-S84 PolarHBondContact O-N 3.43Å; I82-V85 PolarHBondContact O-N 3.26Å; I82-I86 HydrophobicContact CG2-CD1 3.66Å; I82-I86 HydrophobicContact CG2-CG1 4.34Å; I82-I86 WeakPolarHBondContact O-CB 3.22Å; I82-I86 VanDerWaalsContact O-CG1 3.25Å; I82-I86 WeakPolarHBondContact O-CG1 3.23Å; I82-I86 PolarHBondContact O-N 3.05Å
83	L	56.6	Low	57.9	Low	57 Å²	57	72.2 Å²	72.2	30%	0.298	37%	0.368	S	S	.	.	H	α-helix	trans	-61.7	-39.6	177.1	-76.1	172.5	0	0	0	112.1	I79 A80 I81 I86 S87 V121 F124	I79-L83 HydrophobicContact CG2-CD1 3.79Å; I79-L83 HydrophobicContact CG2-CG 4.13Å; I79-L83 WeakPolarHBondContact O-CB 3.41Å; I79-L83 VanDerWaalsContact O-CG 3.31Å; I79-L83 WeakPolarHBondContact O-CG 3.3Å; I79-L83 PolarHBondContact O-N 3.4Å; A80-L83 PolarHBondContact O-N 2.84Å; I81-L83 VanDerWaalsContact C-N 3.35Å; I81-L83 PolarHBondContact O-N 2.91Å; L83-I86 PolarHBondContact O-N 3.25Å; L83-S87 VanDerWaalsContact O-CB 3.25Å; L83-S87 WeakPolarHBondContact O-CB 3.47Å; L83-S87 PolarHBondContact O-N 2.89Å; L83-V121 HydrophobicContact CB-CG2 3.89Å; L83-F124 HydrophobicContact CD1-CD2 4.04Å; L83-F124 HydrophobicContact CD1-CE2 4.37Å
84	S	58.1	Low	57.9	Low	25 Å²	25	70.3 Å²	70.3	18%	0.175	36%	0.358	C	S	.	.	H	α-helix	trans	-64.8	-40.9	175.3	73	0	0	0	0	112.3	A80 I81 I82 S87 M88	A80-S84 WeakPolarHBondContact O-CB 3.45Å; A80-S84 PolarHBondContact O-N 2.89Å; A80-S84 PolarHBondContact O-OG 3.16Å; I81-S84 PolarHBondContact O-N 3.34Å; I81-S84 PolarHBondContact O-OG 3.18Å; I82-S84 VanDerWaalsContact C-N 3.34Å; I82-S84 PolarHBondContact O-N 3.43Å; S84-S87 PolarHBondContact O-N 2.71Å; S84-M88 WeakPolarHBondContact O-CG 3.41Å; S84-M88 PolarHBondContact O-N 3.42Å
85	V	61.1	Low	57.9	Low	88 Å²	88	70.4 Å²	70.4	53%	0.533	35%	0.353	S	S	.	.	H	α-helix	trans	-68.4	-40.9	177	172.1	0	0	0	0	110.9	I81 I82 M88 G89	I81-V85 HydrophobicContact CG2-CG2 4.44Å; I81-V85 WeakPolarHBondContact O-CG2 3.26Å; I81-V85 PolarHBondContact O-N 3.44Å; I82-V85 PolarHBondContact O-N 3.26Å; V85-M88 PolarHBondContact O-N 2.98Å; V85-G89 PolarHBondContact O-N 3.41Å
86	I	61.4	Low	58	Low	76 Å²	76	67.8 Å²	67.8	39%	0.39	34%	0.342	S	S	.	.	H	α-helix	trans	-59.4	-50	172.8	-71.7	168.4	0	0	0	109.5	I82 L83 M88 G89 E90	I82-I86 HydrophobicContact CG2-CD1 3.66Å; I82-I86 HydrophobicContact CG2-CG1 4.34Å; I82-I86 WeakPolarHBondContact O-CB 3.22Å; I82-I86 VanDerWaalsContact O-CG1 3.25Å; I82-I86 WeakPolarHBondContact O-CG1 3.23Å; I82-I86 PolarHBondContact O-N 3.05Å; L83-I86 PolarHBondContact O-N 3.25Å; I86-M88 VanDerWaalsContact C-N 3.35Å; I86-M88 PolarHBondContact O-N 3.33Å; I86-G89 CarbonylContact O-C 3.57Å; I86-G89 PolarHBondContact O-N 3.43Å; I86-G89 VanDerWaalsContact O-N 3.11Å; I86-E90 HydrophobicContact CG2-CG 3.96Å; I86-E90 WeakPolarHBondContact CG2-OE1 3.36Å; I86-E90 VanDerWaalsContact O-CB 3.29Å; I86-E90 WeakPolarHBondContact O-CB 3.36Å; I86-E90 WeakPolarHBondContact O-CG 3.44Å; I86-E90 PolarHBondContact O-N 2.91Å
87	S	59.3	Low	57.6	Low	7 Å²	7	65.7 Å²	65.7	5%	0.049	33%	0.334	C	S	.	.	H	α-helix	trans	-58.2	-42.3	177.7	171.5	0	0	0	0	113	L83 S84 T91 F118	L83-S87 VanDerWaalsContact O-CB 3.25Å; L83-S87 WeakPolarHBondContact O-CB 3.47Å; L83-S87 PolarHBondContact O-N 2.89Å; S84-S87 PolarHBondContact O-N 2.71Å; S87-T91 PolarHBondContact O-N 3.21Å; S87-T91 PolarHBondContact O-OG1 3.3Å; S87-F118 WeakPolarHBondContact OG-CD1 3.27Å; S87-F118 WeakPolarHBondContact OG-CE1 3.48Å; S87-F118 WeakPolarHBondContact OG-CZ 3.27Å
88	M	59.8	Low	57.3	Low	71 Å²	71	63.2 Å²	63.2	35%	0.35	33%	0.326	S	S	.	.	H	α-helix	trans	-62.5	-48.8	172.6	-69.9	-175.7	-150.7	0	0	111.7	S84 V85 I86 E90 T91 I92 F236 F240	S84-M88 WeakPolarHBondContact O-CG 3.41Å; S84-M88 PolarHBondContact O-N 3.42Å; V85-M88 PolarHBondContact O-N 2.98Å; I86-M88 VanDerWaalsContact C-N 3.35Å; I86-M88 PolarHBondContact O-N 3.33Å; M88-E90 VanDerWaalsContact C-N 3.31Å; M88-E90 PolarHBondContact O-N 3.45Å; M88-T91 PolarHBondContact O-N 3.12Å; M88-I92 WeakPolarHBondContact O-CG1 3.5Å; M88-I92 PolarHBondContact O-N 3.28Å; M88-I92 VanDerWaalsContact O-N 3.16Å; M88-F236 HydrophobicContact CG-CE2 4.46Å; M88-F240 HydrophobicContact CE-CE2 3.51Å; M88-F240 HydrophobicContact CE-CZ 4.19Å; M88-F240 HydrophobicContact CG-CE2 4.29Å; M88-F240 HydrophobicContact SD-CE2 3.94Å; M88-F240 HydrophobicContact SD-CZ 4.43Å
89	G	62.5	Low	57.1	Low	39 Å²	39	63.6 Å²	63.6	40%	0.402	33%	0.327	S	S	.	.	H	α-helix	trans	-63.4	-37.1	-179.7	0	0	0	0	0	112.7	V85 I86 I92 A93	V85-G89 PolarHBondContact O-N 3.41Å; I86-G89 CarbonylContact O-C 3.57Å; I86-G89 PolarHBondContact O-N 3.43Å; I86-G89 VanDerWaalsContact O-N 3.11Å; G89-I92 PolarHBondContact O-N 3.49Å; G89-A93 WeakPolarHBondContact O-CB 3.33Å; G89-A93 PolarHBondContact O-N 3.17Å
90	E	56.4	Low	57	Low	59 Å²	59	66.1 Å²	66.1	28%	0.276	34%	0.335	S	S	.	.	H	α-helix	trans	-69.1	-40.3	177.1	-74.2	172.2	153	0	0	111.9	I86 M88 I92 A93 I94 F114	I86-E90 HydrophobicContact CG2-CG 3.96Å; I86-E90 WeakPolarHBondContact CG2-OE1 3.36Å; I86-E90 VanDerWaalsContact O-CB 3.29Å; I86-E90 WeakPolarHBondContact O-CB 3.36Å; I86-E90 WeakPolarHBondContact O-CG 3.44Å; I86-E90 PolarHBondContact O-N 2.91Å; M88-E90 VanDerWaalsContact C-N 3.31Å; M88-E90 PolarHBondContact O-N 3.45Å; E90-I92 VanDerWaalsContact C-N 3.27Å; E90-I92 PolarHBondContact O-N 3.05Å; E90-A93 CarbonylContact O-C 3.56Å; E90-A93 WeakPolarHBondContact O-CA 3.4Å; E90-A93 WeakPolarHBondContact O-CB 3.44Å; E90-A93 PolarHBondContact O-N 2.99Å; E90-I94 VanDerWaalsContact O-CG1 3.28Å; E90-I94 WeakPolarHBondContact O-CG1 3.28Å; E90-I94 PolarHBondContact O-N 2.78Å; E90-F114 HydrophobicContact CB-CD1 4.31Å; E90-F114 HydrophobicContact CB-CE1 3.29Å; E90-F114 HydrophobicContact CB-CZ 3.67Å; E90-F114 VanDerWaalsContact CD-CE1 3.49Å; E90-F114 HydrophobicContact CG-CE1 3.76Å; E90-F114 HydrophobicContact CG-CZ 4.13Å; E90-F114 VanDerWaalsContact OE2-CE1 3.29Å; E90-F114 WeakPolarHBondContact OE2-CE1 3.46Å
91	T	59.1	Low	56.8	Low	22 Å²	22	69.5 Å²	69.5	14%	0.135	36%	0.356	C	S	.	.	H	α-helix	trans	-60.9	-41.2	174.9	-46.2	0	0	0	0	110.9	S87 M88 I94 F95 F236	S87-T91 PolarHBondContact O-N 3.21Å; S87-T91 PolarHBondContact O-OG1 3.3Å; M88-T91 PolarHBondContact O-N 3.12Å; T91-I94 PolarHBondContact O-N 3.36Å; T91-F95 PolarHBondContact O-N 3.01Å; T91-F236 HydrophobicContact CG2-CB 3.89Å; T91-F236 HydrophobicContact CG2-CD1 4.44Å; T91-F236 HydrophobicContact CG2-CD2 3.61Å; T91-F236 HydrophobicContact CG2-CE2 4.23Å; T91-F236 HydrophobicContact CG2-CG 3.72Å; T91-F236 VanDerWaalsContact OG1-CD2 3.32Å; T91-F236 WeakPolarHBondContact OG1-CD2 3.48Å
92	I	61.4	Low	56.7	Low	100 Å²	100	75.9 Å²	75.9	51%	0.513	39%	0.385	S	S	.	.	H	α-helix	trans	-64.2	-42.9	172.8	-64	166.2	0	0	0	110.2	M88 G89 E90 I94 F95 F96	M88-I92 WeakPolarHBondContact O-CG1 3.5Å; M88-I92 PolarHBondContact O-N 3.28Å; M88-I92 VanDerWaalsContact O-N 3.16Å; G89-I92 PolarHBondContact O-N 3.49Å; E90-I92 VanDerWaalsContact C-N 3.27Å; E90-I92 PolarHBondContact O-N 3.05Å; I92-I94 PolarHBondContact O-N 2.95Å; I92-F95 VanDerWaalsContact O-CB 3.27Å; I92-F95 WeakPolarHBondContact O-CB 3.4Å; I92-F95 PolarHBondContact O-N 3.12Å; I92-F96 HydrophobicContact CG2-CD2 4.01Å; I92-F96 HydrophobicContact CG2-CE2 3.66Å; I92-F96 WeakPolarHBondContact O-CD2 3.14Å; I92-F96 PolarHBondContact O-N 3.14Å
93	A	54.9	Low	56.6	Low	40 Å²	40	74.2 Å²	74.2	33%	0.331	38%	0.377	S	S	.	.	H	α-helix	trans	-62.6	-39.1	178.5	0	0	0	0	0	112.4	G89 E90 F95 F96 I97	G89-A93 WeakPolarHBondContact O-CB 3.33Å; G89-A93 PolarHBondContact O-N 3.17Å; E90-A93 CarbonylContact O-C 3.56Å; E90-A93 WeakPolarHBondContact O-CA 3.4Å; E90-A93 WeakPolarHBondContact O-CB 3.44Å; E90-A93 PolarHBondContact O-N 2.99Å; A93-F95 VanDerWaalsContact C-N 3.33Å; A93-F95 PolarHBondContact O-N 2.83Å; A93-F96 CarbonylContact O-C 3.56Å; A93-F96 WeakPolarHBondContact O-CA 3.48Å; A93-F96 WeakPolarHBondContact O-CB 3.47Å; A93-F96 PolarHBondContact O-N 2.96Å; A93-F96 VanDerWaalsContact O-N 3.09Å; A93-I97 VanDerWaalsContact O-CG1 3.29Å; A93-I97 WeakPolarHBondContact O-CG1 3.33Å; A93-I97 PolarHBondContact O-N 3.42Å
94	I	54.5	Low	56.7	Low	7 Å²	7	75.1 Å²	75.1	4%	0.036	39%	0.385	C	S	.	.	H	α-helix	trans	-62.9	-41.6	174.8	-61.8	160.2	0	0	0	111	E90 T91 I92 F96 I97 Q98 F114 L232	E90-I94 VanDerWaalsContact O-CG1 3.28Å; E90-I94 WeakPolarHBondContact O-CG1 3.28Å; E90-I94 PolarHBondContact O-N 2.78Å; T91-I94 PolarHBondContact O-N 3.36Å; I92-I94 PolarHBondContact O-N 2.95Å; I94-F96 PolarHBondContact O-N 3.14Å; I94-I97 PolarHBondContact O-N 3.47Å; I94-Q98 HydrophobicContact CG2-CG 3.95Å; I94-Q98 WeakPolarHBondContact O-CB 3.23Å; I94-Q98 WeakPolarHBondContact O-CG 3.38Å; I94-Q98 PolarHBondContact O-N 2.81Å; I94-F114 HydrophobicContact CD1-CD1 4.3Å; I94-F114 HydrophobicContact CD1-CD2 3.23Å; I94-F114 HydrophobicContact CD1-CE1 4.19Å; I94-F114 HydrophobicContact CD1-CE2 3.04Å; I94-F114 HydrophobicContact CD1-CG 3.92Å; I94-F114 HydrophobicContact CD1-CZ 3.62Å; I94-F114 HydrophobicContact CG1-CD2 4.04Å; I94-F114 HydrophobicContact CG1-CE2 3.36Å; I94-F114 HydrophobicContact CG1-CZ 3.87Å; I94-L232 HydrophobicContact CD1-CD1 3.93Å; I94-L232 HydrophobicContact CG2-CD1 3.89Å
95	F	52.9	Low	56.7	Low	106 Å²	106	83.4 Å²	83.4	47%	0.465	41%	0.414	S	S	.	.	H	α-helix	trans	-54.4	-35.5	174.4	-170.1	-89.1	0	0	0	111.3	T91 I92 A93 F229	T91-F95 PolarHBondContact O-N 3.01Å; I92-F95 VanDerWaalsContact O-CB 3.27Å; I92-F95 WeakPolarHBondContact O-CB 3.4Å; I92-F95 PolarHBondContact O-N 3.12Å; A93-F95 VanDerWaalsContact C-N 3.33Å; A93-F95 PolarHBondContact O-N 2.83Å; F95-F229 HydrophobicContact CD2-CE2 4.07Å; F95-F229 AromaticContact CD2-CZ 3.67Å; F95-F229 HydrophobicContact CD2-CZ 3.67Å; F95-F229 AromaticContact CE2-CZ 3.97Å; F95-F229 HydrophobicContact CE2-CZ 3.97Å
96	F	55.4	Low	56.8	Low	123 Å²	123	83 Å²	83	54%	0.539	41%	0.408	S	S	.	.	H	α-helix	trans	-80.6	-42.8	174.3	-72.6	-71.3	0	0	0	114	I92 A93 I94 Q98 R99	I92-F96 HydrophobicContact CG2-CD2 4.01Å; I92-F96 HydrophobicContact CG2-CE2 3.66Å; I92-F96 WeakPolarHBondContact O-CD2 3.14Å; I92-F96 PolarHBondContact O-N 3.14Å; A93-F96 CarbonylContact O-C 3.56Å; A93-F96 WeakPolarHBondContact O-CA 3.48Å; A93-F96 WeakPolarHBondContact O-CB 3.47Å; A93-F96 PolarHBondContact O-N 2.96Å; A93-F96 VanDerWaalsContact O-N 3.09Å; I94-F96 PolarHBondContact O-N 3.14Å; F96-Q98 VanDerWaalsContact C-N 3.32Å; F96-Q98 PolarHBondContact O-N 2.85Å; F96-R99 WeakPolarHBondContact O-CB 3.5Å; F96-R99 PolarHBondContact O-N 3.45Å; F96-R99 VanDerWaalsContact O-N 3.12Å
97	I	53.5	Low	56.8	Low	51 Å²	51	80.2 Å²	80.2	26%	0.262	40%	0.395	S	S	.	.	H	α-helix	trans	-64.5	-37.2	-177	-71.1	166.4	0	0	0	111.1	A93 I94 R99 F100 L103 T107 L110	A93-I97 VanDerWaalsContact O-CG1 3.29Å; A93-I97 WeakPolarHBondContact O-CG1 3.33Å; A93-I97 PolarHBondContact O-N 3.42Å; I94-I97 PolarHBondContact O-N 3.47Å; I97-R99 PolarHBondContact O-N 3.25Å; I97-R99 VanDerWaalsContact O-N 3.13Å; I97-F100 PolarHBondContact O-N 3.44Å; I97-L103 HydrophobicContact CG2-CB 4.4Å; I97-L103 HydrophobicContact CG2-CD1 3.84Å; I97-T107 HydrophobicContact CG2-CG2 4.13Å; I97-L110 HydrophobicContact CD1-CD1 4.27Å
98	Q	50.2	Low	56.9	Low	41 Å²	41	83.5 Å²	83.5	19%	0.192	41%	0.412	C	S	.	.	T	Hydrogen-bonded Turn	trans	-69.8	-6.9	177.6	-72.4	-174.4	-1.5	0	0	114.3	I94 F96 F100 T107	I94-Q98 HydrophobicContact CG2-CG 3.95Å; I94-Q98 WeakPolarHBondContact O-CB 3.23Å; I94-Q98 WeakPolarHBondContact O-CG 3.38Å; I94-Q98 PolarHBondContact O-N 2.81Å; F96-Q98 VanDerWaalsContact C-N 3.32Å; F96-Q98 PolarHBondContact O-N 2.85Å; Q98-F100 PolarHBondContact O-N 2.86Å; Q98-T107 HydrophobicContact CG-CG2 3.9Å
99	R	52.6	Low	57.1	Low	200 Å²	200	86.4 Å²	86.4	76%	0.755	42%	0.423	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.9	-15.7	167.4	-160.1	167	-177.5	169.4	-0.7	112.1	F96 I97 P101	F96-R99 WeakPolarHBondContact O-CB 3.5Å; F96-R99 PolarHBondContact O-N 3.45Å; F96-R99 VanDerWaalsContact O-N 3.12Å; I97-R99 PolarHBondContact O-N 3.25Å; I97-R99 VanDerWaalsContact O-N 3.13Å; R99-P101 WeakPolarHBondContact O-CD 3.44Å
100	F	54.7	Low	57.2	Low	132 Å²	132	86 Å²	86	58%	0.579	41%	0.411	S	S	*	.			trans	-104.1	101.9	178.4	-59.8	-78.6	0	0	0	110.5	I97 Q98 H102 L103	I97-F100 PolarHBondContact O-N 3.44Å; Q98-F100 PolarHBondContact O-N 2.86Å; F100-H102 PolarHBondContact O-N 3.28Å; F100-L103 HydrophobicContact CB-CD1 3.89Å; F100-L103 HydrophobicContact CB-CG 4.29Å; F100-L103 HydrophobicContact CG-CD1 4.5Å; F100-L103 PolarHBondContact O-N 2.97Å
101	P	52.4	Low	57.6	Low	75 Å²	75	85 Å²	85	49%	0.487	41%	0.405	S	S	.	.	G	3₁₀ helix	trans	-63.8	-12.2	-176.1	24.3	-33.2	0	0	0	114	M1 R99 L103	M1-P101 HydrophobicContact CE-CB 4.25Å; R99-P101 WeakPolarHBondContact O-CD 3.44Å; P101-L103 VanDerWaalsContact C-N 3.33Å
102	H	55.6	Low	57.7	Low	175 Å²	175	88.5 Å²	88.5	81%	0.81	42%	0.422	S	S	*	.	G	3₁₀ helix	trans	-82.8	-5.5	179.9	-59.2	-58	0	0	0	114.3	F100	F100-H102 PolarHBondContact O-N 3.28Å
103	L	57.4	Low	57.9	Low	64 Å²	64	88 Å²	88	34%	0.335	42%	0.42	S	S	.	.	G	3₁₀ helix	trans	-101.4	19.6	-174.1	-68.9	173.9	0	0	0	113.9	I97 F100 P101 Y105 L106 T107	I97-L103 HydrophobicContact CG2-CB 4.4Å; I97-L103 HydrophobicContact CG2-CD1 3.84Å; F100-L103 HydrophobicContact CB-CD1 3.89Å; F100-L103 HydrophobicContact CB-CG 4.29Å; F100-L103 HydrophobicContact CG-CD1 4.5Å; F100-L103 PolarHBondContact O-N 2.97Å; P101-L103 VanDerWaalsContact C-N 3.33Å; L103-Y105 VanDerWaalsContact C-N 3.32Å; L103-Y105 PolarHBondContact O-N 3.48Å; L103-L106 HydrophobicContact CB-CB 4.37Å; L103-L106 HydrophobicContact CD2-CB 4.41Å; L103-L106 HydrophobicContact CD2-CD2 4.03Å; L103-L106 WeakPolarHBondContact O-CA 3.2Å; L103-L106 WeakPolarHBondContact O-CB 3.41Å; L103-L106 PolarHBondContact O-N 3.35Å; L103-T107 PolarHBondContact O-N 3.33Å; L103-T107 PolarHBondContact O-OG1 3.41Å
104	T	58.3	Low	58.3	Low	77 Å²	77	86.5 Å²	86.5	47%	0.472	41%	0.406	S	S	.	.	H	α-helix	trans	-51.1	-44.4	-175.5	48.3	0	0	0	0	114	L106 T107 D108	T104-L106 PolarHBondContact O-N 3.5Å; T104-T107 VanDerWaalsContact CA-OG1 3.29Å; T104-T107 WeakPolarHBondContact CA-OG1 3.26Å; T104-T107 PolarHBondContact O-N 3.46Å; T104-T107 PolarHBondContact O-OG1 3.43Å; T104-D108 VanDerWaalsContact O-CG 3.3Å; T104-D108 PolarHBondContact O-N 3.47Å; T104-D108 VanDerWaalsContact O-OD1 3.1Å
105	Y	57.6	Low	58.6	Low	198 Å²	198	87.2 Å²	87.2	78%	0.776	41%	0.411	S	S	*	.	H	α-helix	trans	-67	-36.9	177.1	-73.2	-74.3	0	0	0	113.4	L103 T107 D108 F109	L103-Y105 VanDerWaalsContact C-N 3.32Å; L103-Y105 PolarHBondContact O-N 3.48Å; Y105-T107 VanDerWaalsContact C-N 3.32Å; Y105-D108 PolarHBondContact O-N 2.88Å; Y105-F109 PolarHBondContact O-N 3.48Å; Y105-F109 VanDerWaalsContact O-N 3.13Å
106	L	62.1	Low	59.1	Low	80 Å²	80	88.2 Å²	88.2	42%	0.419	41%	0.413	S	S	.	.	H	α-helix	trans	-67.2	-39	175.8	-175.9	67.2	0	0	0	109.9	L103 T104 D108 F109 L110	L103-L106 HydrophobicContact CB-CB 4.37Å; L103-L106 HydrophobicContact CD2-CB 4.41Å; L103-L106 HydrophobicContact CD2-CD2 4.03Å; L103-L106 WeakPolarHBondContact O-CA 3.2Å; L103-L106 WeakPolarHBondContact O-CB 3.41Å; L103-L106 PolarHBondContact O-N 3.35Å; T104-L106 PolarHBondContact O-N 3.5Å; L106-D108 VanDerWaalsContact C-N 3.35Å; L106-D108 PolarHBondContact O-N 3.07Å; L106-F109 PolarHBondContact O-N 3.13Å; L106-L110 HydrophobicContact CD1-CD1 4.47Å; L106-L110 HydrophobicContact CD1-CG 4.4Å; L106-L110 HydrophobicContact CD2-CD1 4.41Å; L106-L110 HydrophobicContact CG-CD1 3.88Å; L106-L110 HydrophobicContact CG-CG 4.25Å; L106-L110 WeakPolarHBondContact O-CB 3.3Å; L106-L110 WeakPolarHBondContact O-CG 3.3Å; L106-L110 PolarHBondContact O-N 3.12Å
107	T	61.7	Low	59.5	Low	18 Å²	18	84.2 Å²	84.2	11%	0.11	40%	0.4	C	S	.	.	H	α-helix	trans	-66.7	-34.7	178.5	54.1	0	0	0	0	112.8	I97 Q98 L103 T104 Y105 Y111	I97-T107 HydrophobicContact CG2-CG2 4.13Å; Q98-T107 HydrophobicContact CG-CG2 3.9Å; L103-T107 PolarHBondContact O-N 3.33Å; L103-T107 PolarHBondContact O-OG1 3.41Å; T104-T107 VanDerWaalsContact CA-OG1 3.29Å; T104-T107 WeakPolarHBondContact CA-OG1 3.26Å; T104-T107 PolarHBondContact O-N 3.46Å; T104-T107 PolarHBondContact O-OG1 3.43Å; Y105-T107 VanDerWaalsContact C-N 3.32Å; T107-Y111 WeakPolarHBondContact O-CB 3.25Å; T107-Y111 PolarHBondContact O-N 2.87Å
108	D	62.2	Low	60.1	Low	76 Å²	76	82 Å²	82	41%	0.406	39%	0.389	S	S	.	.	H	α-helix	trans	-72.7	-41.7	177.7	-66.7	7.5	0	0	0	111.6	T104 Y105 L106 Y111 L112 I228	T104-D108 VanDerWaalsContact O-CG 3.3Å; T104-D108 PolarHBondContact O-N 3.47Å; T104-D108 VanDerWaalsContact O-OD1 3.1Å; Y105-D108 PolarHBondContact O-N 2.88Å; L106-D108 VanDerWaalsContact C-N 3.35Å; L106-D108 PolarHBondContact O-N 3.07Å; D108-Y111 WeakPolarHBondContact O-CB 3.31Å; D108-Y111 PolarHBondContact O-N 3.47Å; D108-L112 PolarHBondContact O-N 3.38Å; D108-I228 WeakPolarHBondContact OD1-CD1 3.16Å
109	F	63.5	Low	60.7	Low	131 Å²	131	80.2 Å²	80.2	58%	0.575	38%	0.381	S	S	*	.	H	α-helix	trans	-64.5	-45.5	173.8	176.1	-99.8	0	0	0	111.4	Y105 L106 Y111 L112 L113	Y105-F109 PolarHBondContact O-N 3.48Å; Y105-F109 VanDerWaalsContact O-N 3.13Å; L106-F109 PolarHBondContact O-N 3.13Å; F109-Y111 VanDerWaalsContact C-N 3.28Å; F109-Y111 PolarHBondContact O-N 3.48Å; F109-L112 PolarHBondContact O-N 3.42Å; F109-L113 PolarHBondContact O-N 3.48Å
110	L	65.3	Low	61.2	Low	31 Å²	31	72 Å²	72	16%	0.162	36%	0.358	C	S	.	.	H	α-helix	trans	-57.2	-44.3	173.9	-81.5	176.3	0	0	0	110.6	I97 L106 L112 L113 F114	I97-L110 HydrophobicContact CD1-CD1 4.27Å; L106-L110 HydrophobicContact CD1-CD1 4.47Å; L106-L110 HydrophobicContact CD1-CG 4.4Å; L106-L110 HydrophobicContact CD2-CD1 4.41Å; L106-L110 HydrophobicContact CG-CD1 3.88Å; L106-L110 HydrophobicContact CG-CG 4.25Å; L106-L110 WeakPolarHBondContact O-CB 3.3Å; L106-L110 WeakPolarHBondContact O-CG 3.3Å; L106-L110 PolarHBondContact O-N 3.12Å; L110-L112 PolarHBondContact O-N 3.33Å; L110-L113 CarbonylContact O-C 3.6Å; L110-L113 WeakPolarHBondContact O-CB 3.38Å; L110-L113 PolarHBondContact O-N 3.06Å; L110-L113 VanDerWaalsContact O-N 3.16Å; L110-F114 HydrophobicContact CB-CD2 3.99Å; L110-F114 HydrophobicContact CB-CE2 3.64Å; L110-F114 HydrophobicContact CD2-CE2 3.93Å; L110-F114 HydrophobicContact CD2-CZ 4.21Å; L110-F114 HydrophobicContact CG-CE2 4.23Å; L110-F114 WeakPolarHBondContact O-CB 3.39Å; L110-F114 WeakPolarHBondContact O-CD2 3.46Å; L110-F114 VanDerWaalsContact O-CG 3.29Å; L110-F114 WeakPolarHBondContact O-CG 3.01Å; L110-F114 PolarHBondContact O-N 3.17Å
111	Y	64.4	Low	61.6	Low	38 Å²	38	66.1 Å²	66.1	15%	0.149	33%	0.333	C	S	.	.	H	α-helix	trans	-53.3	-50.1	176.3	179.9	-100	0	0	0	112.5	T49 T107 D108 F109 L113 F114 T115 I228 S231 L232	T49-Y111 WeakPolarHBondContact CB-OH 3.22Å; T107-Y111 WeakPolarHBondContact O-CB 3.25Å; T107-Y111 PolarHBondContact O-N 2.87Å; D108-Y111 WeakPolarHBondContact O-CB 3.31Å; D108-Y111 PolarHBondContact O-N 3.47Å; F109-Y111 VanDerWaalsContact C-N 3.28Å; F109-Y111 PolarHBondContact O-N 3.48Å; Y111-L113 VanDerWaalsContact C-N 3.34Å; Y111-L113 PolarHBondContact O-N 3.37Å; Y111-F114 WeakPolarHBondContact O-CB 3.48Å; Y111-F114 PolarHBondContact O-N 2.78Å; Y111-F114 VanDerWaalsContact O-N 3.17Å; Y111-T115 PolarHBondContact O-N 3.3Å; Y111-T115 PolarHBondContact O-OG1 3.27Å; Y111-I228 HydrophobicContact CD2-CG2 3.45Å; Y111-I228 VanDerWaalsContact CD2-CG2 3.45Å; Y111-I228 HydrophobicContact CE2-CG2 4.13Å; Y111-I228 HydrophobicContact CG-CG2 3.7Å; Y111-S231 WeakPolarHBondContact CE2-OG 3.26Å; Y111-S231 PolarHBondContact OH-OG 3.21Å; Y111-L232 HydrophobicContact CD2-CD1 3.86Å; Y111-L232 HydrophobicContact CD2-CD2 3.37Å; Y111-L232 HydrophobicContact CD2-CG 3.41Å; Y111-L232 VanDerWaalsContact CD2-CG 3.41Å; Y111-L232 HydrophobicContact CE2-CD2 3.62Å; Y111-L232 HydrophobicContact CE2-CG 3.64Å; Y111-L232 HydrophobicContact CG-CD2 4.49Å
112	L	61.6	Low	62.3	Low	95 Å²	95	62.5 Å²	62.5	50%	0.497	31%	0.31	S	S	.	.	H	α-helix	trans	-61.5	-44.6	178.4	-171.5	75.3	0	0	0	111.4	D108 F109 L110 F114 T115 Y116	D108-L112 PolarHBondContact O-N 3.38Å; F109-L112 PolarHBondContact O-N 3.42Å; L110-L112 PolarHBondContact O-N 3.33Å; L112-F114 VanDerWaalsContact C-N 3.27Å; L112-F114 PolarHBondContact O-N 2.84Å; L112-T115 WeakPolarHBondContact O-CB 3.5Å; L112-T115 PolarHBondContact O-N 3.46Å; L112-Y116 HydrophobicContact CD1-CE2 4.02Å; L112-Y116 HydrophobicContact CG-CD2 4.28Å; L112-Y116 HydrophobicContact CG-CE2 4.06Å; L112-Y116 VanDerWaalsContact O-CD2 3.23Å; L112-Y116 WeakPolarHBondContact O-CD2 3.41Å; L112-Y116 PolarHBondContact O-N 2.86Å
113	L	64.8	Low	62.7	Low	90 Å²	90	54.5 Å²	54.5	47%	0.471	27%	0.273	S	S	.	.	H	α-helix	trans	-60.6	-39.8	176.4	-169.3	72.3	0	0	0	111.2	F109 L110 Y111 Y116 S117	F109-L113 PolarHBondContact O-N 3.48Å; L110-L113 CarbonylContact O-C 3.6Å; L110-L113 WeakPolarHBondContact O-CB 3.38Å; L110-L113 PolarHBondContact O-N 3.06Å; L110-L113 VanDerWaalsContact O-N 3.16Å; Y111-L113 VanDerWaalsContact C-N 3.34Å; Y111-L113 PolarHBondContact O-N 3.37Å; L113-Y116 PolarHBondContact O-N 2.88Å; L113-S117 WeakPolarHBondContact O-CB 3.29Å; L113-S117 PolarHBondContact O-N 3.41Å
114	F	63.6	Low	63	Low	8 Å²	8	54.9 Å²	54.9	4%	0.035	27%	0.272	C	S	.	.	H	α-helix	trans	-65.1	-46.4	177.6	-76.9	-53.1	0	0	0	112.4	E90 I94 L110 Y111 L112 Y116 S117 F118 L232	E90-F114 HydrophobicContact CB-CD1 4.31Å; E90-F114 HydrophobicContact CB-CE1 3.29Å; E90-F114 HydrophobicContact CB-CZ 3.67Å; E90-F114 VanDerWaalsContact CD-CE1 3.49Å; E90-F114 HydrophobicContact CG-CE1 3.76Å; E90-F114 HydrophobicContact CG-CZ 4.13Å; E90-F114 VanDerWaalsContact OE2-CE1 3.29Å; E90-F114 WeakPolarHBondContact OE2-CE1 3.46Å; I94-F114 HydrophobicContact CD1-CD1 4.3Å; I94-F114 HydrophobicContact CD1-CD2 3.23Å; I94-F114 HydrophobicContact CD1-CE1 4.19Å; I94-F114 HydrophobicContact CD1-CE2 3.04Å; I94-F114 HydrophobicContact CD1-CG 3.92Å; I94-F114 HydrophobicContact CD1-CZ 3.62Å; I94-F114 HydrophobicContact CG1-CD2 4.04Å; I94-F114 HydrophobicContact CG1-CE2 3.36Å; I94-F114 HydrophobicContact CG1-CZ 3.87Å; L110-F114 HydrophobicContact CB-CD2 3.99Å; L110-F114 HydrophobicContact CB-CE2 3.64Å; L110-F114 HydrophobicContact CD2-CE2 3.93Å; L110-F114 HydrophobicContact CD2-CZ 4.21Å; L110-F114 HydrophobicContact CG-CE2 4.23Å; L110-F114 WeakPolarHBondContact O-CB 3.39Å; L110-F114 WeakPolarHBondContact O-CD2 3.46Å; L110-F114 VanDerWaalsContact O-CG 3.29Å; L110-F114 WeakPolarHBondContact O-CG 3.01Å; L110-F114 PolarHBondContact O-N 3.17Å; Y111-F114 WeakPolarHBondContact O-CB 3.48Å; Y111-F114 PolarHBondContact O-N 2.78Å; Y111-F114 VanDerWaalsContact O-N 3.17Å; L112-F114 VanDerWaalsContact C-N 3.27Å; L112-F114 PolarHBondContact O-N 2.84Å; F114-Y116 PolarHBondContact O-N 2.99Å; F114-S117 WeakPolarHBondContact CA-OG 3.19Å; F114-S117 PolarHBondContact O-N 3.23Å; F114-S117 VanDerWaalsContact O-N 3.15Å; F114-S117 PolarHBondContact O-OG 3.4Å; F114-S117 VanDerWaalsContact O-OG 3.12Å; F114-F118 HydrophobicContact CB-CD2 4.21Å; F114-F118 HydrophobicContact CB-CE2 4.27Å; F114-F118 HydrophobicContact CD1-CE2 4.41Å; F114-F118 WeakPolarHBondContact O-CB 3.34Å; F114-F118 WeakPolarHBondContact O-CD2 3.37Å; F114-F118 PolarHBondContact O-N 3.27Å; F114-L232 HydrophobicContact CB-CD2 4.18Å
115	T	61.5	Low	63.3	Low	22 Å²	22	53 Å²	53	14%	0.135	26%	0.259	C	S	.	.	H	α-helix	trans	-50.8	-46.5	173.2	-63.9	0	0	0	0	110.3	Q53 Y111 L112 A119	Q53-T115 PolarHBondContact NE2-O 3.16Å; Q53-T115 PolarHBondContact OE1-O 3.19Å; Y111-T115 PolarHBondContact O-N 3.3Å; Y111-T115 PolarHBondContact O-OG1 3.27Å; L112-T115 WeakPolarHBondContact O-CB 3.5Å; L112-T115 PolarHBondContact O-N 3.46Å; T115-A119 PolarHBondContact O-N 3.43Å
116	Y	61.7	Low	63.6	Low	128 Å²	128	43.5 Å²	43.5	50%	0.502	22%	0.222	S	C	.	.	H	α-helix	trans	-73.3	-38.4	176.6	-74.9	-71.2	0	0	0	114.3	L56 L112 L113 F114 A119 G120	L56-Y116 HydrophobicContact CD2-CD1 4.3Å; L56-Y116 HydrophobicContact CD2-CE1 3.99Å; L112-Y116 HydrophobicContact CD1-CE2 4.02Å; L112-Y116 HydrophobicContact CG-CD2 4.28Å; L112-Y116 HydrophobicContact CG-CE2 4.06Å; L112-Y116 VanDerWaalsContact O-CD2 3.23Å; L112-Y116 WeakPolarHBondContact O-CD2 3.41Å; L112-Y116 PolarHBondContact O-N 2.86Å; L113-Y116 PolarHBondContact O-N 2.88Å; F114-Y116 PolarHBondContact O-N 2.99Å; Y116-A119 PolarHBondContact O-N 2.86Å; Y116-G120 PolarHBondContact O-N 2.84Å
117	S	65.1	Low	63.6	Low	39 Å²	39	40.5 Å²	40.5	27%	0.273	21%	0.206	S	C	.	.	H	α-helix	trans	-65.9	-42.4	-179.9	73.2	0	0	0	0	111.5	L113 F114 G120 V121	L113-S117 WeakPolarHBondContact O-CB 3.29Å; L113-S117 PolarHBondContact O-N 3.41Å; F114-S117 WeakPolarHBondContact CA-OG 3.19Å; F114-S117 PolarHBondContact O-N 3.23Å; F114-S117 VanDerWaalsContact O-N 3.15Å; F114-S117 PolarHBondContact O-OG 3.4Å; F114-S117 VanDerWaalsContact O-OG 3.12Å; S117-G120 PolarHBondContact O-N 3.15Å; S117-V121 WeakPolarHBondContact O-CG2 3.11Å; S117-V121 PolarHBondContact O-N 2.97Å
118	F	64.9	Low	63.5	Low	4 Å²	4	41.1 Å²	41.1	2%	0.018	21%	0.209	C	C	.	.	H	α-helix	trans	-61.6	-45.5	174.8	-83.3	-68.5	0	0	0	112	S87 F114 G120 V121 I122 L235 F236 T239	S87-F118 WeakPolarHBondContact OG-CD1 3.27Å; S87-F118 WeakPolarHBondContact OG-CE1 3.48Å; S87-F118 WeakPolarHBondContact OG-CZ 3.27Å; F114-F118 HydrophobicContact CB-CD2 4.21Å; F114-F118 HydrophobicContact CB-CE2 4.27Å; F114-F118 HydrophobicContact CD1-CE2 4.41Å; F114-F118 WeakPolarHBondContact O-CB 3.34Å; F114-F118 WeakPolarHBondContact O-CD2 3.37Å; F114-F118 PolarHBondContact O-N 3.27Å; F118-G120 VanDerWaalsContact C-N 3.29Å; F118-G120 PolarHBondContact O-N 2.9Å; F118-V121 PolarHBondContact O-N 3.02Å; F118-I122 WeakPolarHBondContact O-CB 3.45Å; F118-I122 WeakPolarHBondContact O-CD1 3.43Å; F118-I122 WeakPolarHBondContact O-CG1 3.38Å; F118-I122 PolarHBondContact O-N 2.93Å; F118-L235 HydrophobicContact CD2-CD2 3.95Å; F118-L235 HydrophobicContact CD2-CG 4.34Å; F118-L235 HydrophobicContact CG-CD2 4.46Å; F118-F236 HydrophobicContact CE1-CD2 4.39Å; F118-F236 HydrophobicContact CZ-CD2 4.24Å; F118-T239 HydrophobicContact CD1-CG2 3.91Å; F118-T239 HydrophobicContact CE1-CG2 4.39Å
119	A	63	Low	63.4	Low	3 Å²	3	38 Å²	38	3%	0.025	19%	0.192	C	C	.	.	H	α-helix	trans	-59.4	-42.8	175.8	0	0	0	0	0	111	T115 Y116 T123	T115-A119 PolarHBondContact O-N 3.43Å; Y116-A119 PolarHBondContact O-N 2.86Å; A119-T123 WeakPolarHBondContact O-CB 3.4Å; A119-T123 PolarHBondContact O-N 2.92Å; A119-T123 PolarHBondContact O-OG1 3.3Å
120	G	63.4	Low	63.1	Low	28 Å²	28	39.6 Å²	39.6	29%	0.289	20%	0.202	S	C	.	.	H	α-helix	trans	-61.1	-49.7	174.2	0	0	0	0	0	113.3	Y116 S117 F118 I122 T123 F124	Y116-G120 PolarHBondContact O-N 2.84Å; S117-G120 PolarHBondContact O-N 3.15Å; F118-G120 VanDerWaalsContact C-N 3.29Å; F118-G120 PolarHBondContact O-N 2.9Å; G120-I122 VanDerWaalsContact C-N 3.34Å; G120-I122 PolarHBondContact O-N 3.26Å; G120-T123 PolarHBondContact O-N 3.19Å; G120-F124 WeakPolarHBondContact O-CD2 3.45Å; G120-F124 PolarHBondContact O-N 3.41Å
121	V	63.7	Low	62.8	Low	8 Å²	8	39.5 Å²	39.5	5%	0.048	21%	0.208	C	C	.	.	H	α-helix	trans	-58.8	-45.8	178.5	177.5	0	0	0	0	110.8	L83 S117 F118 F124 L125	L83-V121 HydrophobicContact CB-CG2 3.89Å; S117-V121 WeakPolarHBondContact O-CG2 3.11Å; S117-V121 PolarHBondContact O-N 2.97Å; F118-V121 PolarHBondContact O-N 3.02Å; V121-F124 PolarHBondContact O-N 3.4Å; V121-L125 HydrophobicContact CG1-CD1 4.03Å; V121-L125 HydrophobicContact CG1-CG 4.37Å; V121-L125 WeakPolarHBondContact O-CG 3.31Å; V121-L125 PolarHBondContact O-N 2.85Å
122	I	67.5	Low	62.7	Low	0 Å²	0	39.4 Å²	39.4	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-59.5	-48.4	176.1	-72.1	164.2	0	0	0	110.3	F118 G120 F124 L125 S126 W138 T239 Y242	F118-I122 WeakPolarHBondContact O-CB 3.45Å; F118-I122 WeakPolarHBondContact O-CD1 3.43Å; F118-I122 WeakPolarHBondContact O-CG1 3.38Å; F118-I122 PolarHBondContact O-N 2.93Å; G120-I122 VanDerWaalsContact C-N 3.34Å; G120-I122 PolarHBondContact O-N 3.26Å; I122-F124 VanDerWaalsContact C-N 3.29Å; I122-F124 PolarHBondContact O-N 3.28Å; I122-L125 PolarHBondContact O-N 3.11Å; I122-S126 VanDerWaalsContact O-CB 3.31Å; I122-S126 WeakPolarHBondContact O-CB 3.3Å; I122-S126 PolarHBondContact O-N 2.66Å; I122-S126 PolarHBondContact O-OG 3.19Å; I122-W138 HydrophobicContact CD1-CH2 3.95Å; I122-W138 HydrophobicContact CD1-CZ2 3.92Å; I122-W138 HydrophobicContact CG1-CZ2 4.5Å; I122-W138 HydrophobicContact CG2-CZ2 3.61Å; I122-T239 HydrophobicContact CD1-CG2 3.73Å; I122-T239 HydrophobicContact CG1-CG2 3.66Å; I122-Y242 HydrophobicContact CG1-CD1 4.34Å; I122-Y242 HydrophobicContact CG2-CD1 4.07Å; I122-Y242 HydrophobicContact CG2-CE1 3.62Å
123	T	63.7	Low	63	Low	7 Å²	7	36.4 Å²	36.4	4%	0.043	19%	0.193	C	C	.	.	H	α-helix	trans	-58.7	-43.2	178.5	-65.6	0	0	0	0	110.8	T61 V64 A119 G120 S126 I127	T61-T123 PolarHBondContact N-OG1 3.18Å; T61-T123 WeakPolarHBondContact OG1-CA 3.34Å; T61-T123 PolarHBondContact OG1-OG1 2.85Å; V64-T123 HydrophobicContact CB-CG2 3.87Å; V64-T123 HydrophobicContact CG1-CG2 4.34Å; V64-T123 HydrophobicContact CG2-CG2 3.54Å; A119-T123 WeakPolarHBondContact O-CB 3.4Å; A119-T123 PolarHBondContact O-N 2.92Å; A119-T123 PolarHBondContact O-OG1 3.3Å; G120-T123 PolarHBondContact O-N 3.19Å; T123-S126 WeakPolarHBondContact O-CB 3.25Å; T123-S126 PolarHBondContact O-N 3.08Å; T123-I127 WeakPolarHBondContact O-CG1 3.34Å; T123-I127 PolarHBondContact O-N 3.26Å; T123-I127 VanDerWaalsContact O-N 3.13Å
124	F	63.8	Low	63.2	Low	71 Å²	71	32.1 Å²	32.1	31%	0.311	17%	0.17	S	C	.	.	H	α-helix	trans	-65.7	-40.6	175.6	-80.9	-64.7	0	0	0	114.2	L73 A80 L83 G120 V121 I122 S126 I127 N128	L73-F124 HydrophobicContact CD1-CE1 4.05Å; L73-F124 HydrophobicContact CD2-CE1 3.54Å; L73-F124 HydrophobicContact CD2-CZ 4.22Å; L73-F124 HydrophobicContact CG-CE1 4.23Å; A80-F124 HydrophobicContact CB-CB 4.3Å; L83-F124 HydrophobicContact CD1-CD2 4.04Å; L83-F124 HydrophobicContact CD1-CE2 4.37Å; G120-F124 WeakPolarHBondContact O-CD2 3.45Å; G120-F124 PolarHBondContact O-N 3.41Å; V121-F124 PolarHBondContact O-N 3.4Å; I122-F124 VanDerWaalsContact C-N 3.29Å; I122-F124 PolarHBondContact O-N 3.28Å; F124-S126 VanDerWaalsContact C-N 3.26Å; F124-S126 PolarHBondContact O-N 3.13Å; F124-I127 HydrophobicContact CD1-CD1 3.92Å; F124-I127 HydrophobicContact CE1-CD1 4.33Å; F124-I127 PolarHBondContact O-N 3.28Å; F124-N128 PolarHBondContact O-ND2 3.33Å
125	L	63.5	Low	63.4	Low	37 Å²	37	31.8 Å²	31.8	19%	0.194	17%	0.168	C	C	.	.	H	α-helix	trans	-64.8	-35.3	174.5	-73.6	173.5	0	0	0	111.6	V121 I122 I246	V121-L125 HydrophobicContact CG1-CD1 4.03Å; V121-L125 HydrophobicContact CG1-CG 4.37Å; V121-L125 WeakPolarHBondContact O-CG 3.31Å; V121-L125 PolarHBondContact O-N 2.85Å; I122-L125 PolarHBondContact O-N 3.11Å; L125-I246 HydrophobicContact CB-CD1 4.37Å
126	S	65.3	Low	63.8	Low	0 Å²	0	33.4 Å²	33.4	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-66.8	-38.4	179.6	-57.7	0	0	0	0	111.6	Y65 I122 T123 F124 N128 V129 I134 Y242	Y65-S126 PolarHBondContact OH-O 2.89Å; I122-S126 VanDerWaalsContact O-CB 3.31Å; I122-S126 WeakPolarHBondContact O-CB 3.3Å; I122-S126 PolarHBondContact O-N 2.66Å; I122-S126 PolarHBondContact O-OG 3.19Å; T123-S126 WeakPolarHBondContact O-CB 3.25Å; T123-S126 PolarHBondContact O-N 3.08Å; F124-S126 VanDerWaalsContact C-N 3.26Å; F124-S126 PolarHBondContact O-N 3.13Å; S126-N128 PolarHBondContact O-N 3.45Å; S126-N128 VanDerWaalsContact O-N 3.11Å; S126-V129 PolarHBondContact O-N 2.96Å; S126-I134 VanDerWaalsContact O-CD1 3.27Å; S126-I134 WeakPolarHBondContact O-CD1 3.25Å; S126-Y242 PolarHBondContact OG-OH 3.36Å; S126-Y242 VanDerWaalsContact OG-OH 3.08Å
127	I	62.3	Low	64.6	Low	16 Å²	16	27.3 Å²	27.3	8%	0.082	15%	0.152	C	C	.	.	H	α-helix	trans	-52.7	-36.6	-179.5	-70.8	164.3	0	0	0	112.7	V64 Y65 V70 L73 T123 F124 V129	V64-I127 HydrophobicContact CG1-CD1 3.76Å; V64-I127 HydrophobicContact CG1-CG1 4.11Å; Y65-I127 VanDerWaalsContact OH-CA 3.26Å; Y65-I127 WeakPolarHBondContact OH-CA 3.39Å; Y65-I127 PolarHBondContact OH-O 3.32Å; V70-I127 HydrophobicContact CG1-CG2 3.82Å; L73-I127 HydrophobicContact CB-CD1 4.31Å; L73-I127 HydrophobicContact CD1-CD1 3.8Å; T123-I127 WeakPolarHBondContact O-CG1 3.34Å; T123-I127 PolarHBondContact O-N 3.26Å; T123-I127 VanDerWaalsContact O-N 3.13Å; F124-I127 HydrophobicContact CD1-CD1 3.92Å; F124-I127 HydrophobicContact CE1-CD1 4.33Å; F124-I127 PolarHBondContact O-N 3.28Å; I127-V129 PolarHBondContact O-N 3.39Å
128	N	58.9	Low	65.2	Low	32 Å²	32	25.6 Å²	25.6	17%	0.171	14%	0.139	C	C	.	.	T	Hydrogen-bonded Turn	trans	-79.3	-3.8	-176.5	-55	-41.5	0	0	0	113.5	Y77 F124 S126	Y77-N128 WeakPolarHBondContact CD2-ND2 3.48Å; F124-N128 PolarHBondContact O-ND2 3.33Å; S126-N128 PolarHBondContact O-N 3.45Å; S126-N128 VanDerWaalsContact O-N 3.11Å
129	V	60.4	Low	65.7	Low	9 Å²	9	28.1 Å²	28.1	6%	0.055	15%	0.153	C	C	.	.	S	Bend	trans	-109.5	128	179.7	-179	0	0	0	0	109.1	Y65 S126 I127 G131 F133 I134 I246	Y65-V129 PolarHBondContact OH-O 3.11Å; S126-V129 PolarHBondContact O-N 2.96Å; I127-V129 PolarHBondContact O-N 3.39Å; V129-G131 PolarHBondContact O-N 2.72Å; V129-F133 HydrophobicContact CG1-CB 3.56Å; V129-I134 HydrophobicContact CB-CG1 4.01Å; V129-I134 HydrophobicContact CG1-CG1 4.2Å; V129-I246 HydrophobicContact CG2-CG1 4.42Å; V129-I246 HydrophobicContact CG2-CG2 3.77Å
130	E	57.3	Low	66.6	Low	166 Å²	166	31.4 Å²	31.4	78%	0.776	17%	0.169	S	C	*	.			trans	-71.7	129.5	178.1	-66.9	-175.2	175.8	0	0	111.8
131	G	59.5	Low	67.6	Low	29 Å²	29	30.1 Å²	30.1	30%	0.299	16%	0.156	S	C	.	.	T	Hydrogen-bonded Turn	trans	68.2	-132.3	156.2	0	0	0	0	0	116.1	V129 F133 M264	V129-G131 PolarHBondContact O-N 2.72Å; G131-F133 VanDerWaalsContact C-N 3.27Å; G131-F133 PolarHBondContact O-N 2.75Å; G131-M264 VanDerWaalsContact CA-SD 3.58Å
132	M	62.5	Low	68.5	Low	35 Å²	35	32.1 Å²	32.1	17%	0.172	17%	0.166	C	C	.	.	T	Hydrogen-bonded Turn	trans	-71.6	-14.5	-169.4	-68.9	-169.2	177.8	0	0	115.1	I134 F135 I136 I259	M132-I134 VanDerWaalsContact C-N 3.27Å; M132-I134 PolarHBondContact O-N 3.43Å; M132-F135 PolarHBondContact O-N 3.38Å; M132-I136 HydrophobicContact CB-CD1 4.38Å; M132-I136 WeakPolarHBondContact O-CG1 3.38Å; M132-I136 PolarHBondContact O-N 2.96Å; M132-I259 HydrophobicContact CE-CB 3.47Å; M132-I259 VanDerWaalsContact CE-CB 3.47Å; M132-I259 HydrophobicContact CE-CD1 3.61Å; M132-I259 HydrophobicContact CE-CG1 4.02Å; M132-I259 HydrophobicContact CE-CG2 3.33Å; M132-I259 HydrophobicContact SD-CB 4.14Å; M132-I259 HydrophobicContact SD-CD1 3.65Å; M132-I259 HydrophobicContact SD-CG1 4.2Å
133	F	66.5	Low	69.1	Low	33 Å²	33	36.4 Å²	36.4	15%	0.145	19%	0.188	C	C	.	.	H	α-helix	trans	-65.5	-30.6	-176	-73	-70	0	0	0	113.2	V129 G131 F135 I136 S137 V253	V129-F133 HydrophobicContact CG1-CB 3.56Å; G131-F133 VanDerWaalsContact C-N 3.27Å; G131-F133 PolarHBondContact O-N 2.75Å; F133-F135 PolarHBondContact O-N 3.24Å; F133-I136 HydrophobicContact CD1-CD1 4.37Å; F133-I136 HydrophobicContact CE1-CD1 4.41Å; F133-S137 WeakPolarHBondContact O-CB 3.42Å; F133-S137 PolarHBondContact O-N 2.66Å; F133-S137 PolarHBondContact O-OG 3.28Å; F133-V253 HydrophobicContact CD1-CB 4.31Å; F133-V253 HydrophobicContact CE1-CB 3.42Å; F133-V253 VanDerWaalsContact CE1-CB 3.42Å; F133-V253 HydrophobicContact CE1-CG1 3.47Å; F133-V253 VanDerWaalsContact CE1-CG1 3.47Å; F133-V253 HydrophobicContact CE1-CG2 3.9Å; F133-V253 HydrophobicContact CE2-CB 4.26Å; F133-V253 HydrophobicContact CE2-CG1 4.23Å; F133-V253 VanDerWaalsContact CE2-O 3.23Å; F133-V253 WeakPolarHBondContact CE2-O 3.42Å; F133-V253 HydrophobicContact CZ-CB 3.42Å; F133-V253 VanDerWaalsContact CZ-CB 3.42Å; F133-V253 HydrophobicContact CZ-CG1 3.18Å; F133-V253 HydrophobicContact CZ-CG2 4.38Å; F133-V253 WeakPolarHBondContact CZ-O 3.35Å
134	I	69.4	Low	70.2	Confident	0 Å²	0	37.8 Å²	37.8	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-55.1	-45.1	170.6	-64.2	165	0	0	0	109.8	T61 Y65 S126 V129 M132 W138 Y242	T61-I134 HydrophobicContact CG2-CG2 4.3Å; Y65-I134 HydrophobicContact CE2-CD1 3.65Å; Y65-I134 VanDerWaalsContact OH-CD1 3.23Å; Y65-I134 WeakPolarHBondContact OH-CD1 3.35Å; S126-I134 VanDerWaalsContact O-CD1 3.27Å; S126-I134 WeakPolarHBondContact O-CD1 3.25Å; V129-I134 HydrophobicContact CB-CG1 4.01Å; V129-I134 HydrophobicContact CG1-CG1 4.2Å; M132-I134 VanDerWaalsContact C-N 3.27Å; M132-I134 PolarHBondContact O-N 3.43Å; I134-W138 VanDerWaalsContact O-CD1 3.3Å; I134-W138 PolarHBondContact O-N 2.92Å; I134-W138 VanDerWaalsContact O-N 3.11Å; I134-Y242 WeakPolarHBondContact CG2-OH 3.38Å; I134-Y242 WeakPolarHBondContact O-CE2 3.27Å; I134-Y242 PolarHBondContact O-OH 3.48Å
135	F	67.2	Low	71.2	Confident	0 Å²	0	35.8 Å²	35.8	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-80.8	-39.2	-175.5	-56.1	-63.9	0	0	0	112.5	I58 M132 F133 S137 W138 I139 M264 F267 I268 I271	I58-F135 HydrophobicContact CG2-CE1 4.12Å; M132-F135 PolarHBondContact O-N 3.38Å; F133-F135 PolarHBondContact O-N 3.24Å; F135-S137 VanDerWaalsContact C-N 3.26Å; F135-S137 PolarHBondContact O-N 2.84Å; F135-W138 PolarHBondContact O-N 3.46Å; F135-I139 WeakPolarHBondContact O-CG1 3.11Å; F135-I139 PolarHBondContact O-N 2.8Å; F135-M264 HydrophobicContact CD2-CG 4.12Å; F135-M264 HydrophobicContact CE2-CG 3.62Å; F135-M264 HydrophobicContact CE2-SD 3.87Å; F135-F267 HydrophobicContact CB-CD1 3.78Å; F135-F267 HydrophobicContact CB-CE1 3.57Å; F135-F267 HydrophobicContact CD2-CD1 4.46Å; F135-F267 HydrophobicContact CG-CD1 4.21Å; F135-F267 HydrophobicContact CG-CE1 4.47Å; F135-I268 HydrophobicContact CD1-CG1 3.99Å; F135-I268 HydrophobicContact CD2-CG1 4.01Å; F135-I268 HydrophobicContact CE1-CD1 3.96Å; F135-I268 HydrophobicContact CE1-CG1 3.44Å; F135-I268 VanDerWaalsContact CE1-CG1 3.44Å; F135-I268 HydrophobicContact CE2-CD1 3.53Å; F135-I268 HydrophobicContact CE2-CG1 3.45Å; F135-I268 VanDerWaalsContact CE2-CG1 3.45Å; F135-I268 HydrophobicContact CG-CG1 4.28Å; F135-I268 HydrophobicContact CZ-CD1 3.21Å; F135-I268 HydrophobicContact CZ-CG1 3.16Å; F135-I271 HydrophobicContact CB-CD1 3.77Å; F135-I271 HydrophobicContact CD1-CD1 4.27Å; F135-I271 HydrophobicContact CG-CD1 4.29Å
136	I	71.5	Confident	72.1	Confident	57 Å²	57	37.3 Å²	37.3	29%	0.292	20%	0.2	S	C	.	.	H	α-helix	trans	-59.3	-42.8	171.4	-65.2	168.9	0	0	0	109.6	M132 F133 W138 I139 L140	M132-I136 HydrophobicContact CB-CD1 4.38Å; M132-I136 WeakPolarHBondContact O-CG1 3.38Å; M132-I136 PolarHBondContact O-N 2.96Å; F133-I136 HydrophobicContact CD1-CD1 4.37Å; F133-I136 HydrophobicContact CE1-CD1 4.41Å; I136-W138 VanDerWaalsContact C-N 3.33Å; I136-W138 PolarHBondContact O-N 3.25Å; I136-I139 PolarHBondContact O-N 3.02Å; I136-L140 HydrophobicContact CG2-CD1 3.83Å; I136-L140 HydrophobicContact CG2-CG 4.21Å; I136-L140 WeakPolarHBondContact O-CB 3.11Å; I136-L140 VanDerWaalsContact O-CG 3.28Å; I136-L140 WeakPolarHBondContact O-CG 3.41Å; I136-L140 PolarHBondContact O-N 2.87Å
137	S	77.2	Confident	73	Confident	0 Å²	0	41.9 Å²	41.9	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-61.2	-41.3	176.1	-62.7	0	0	0	0	111.7	F133 F135 T141	F133-S137 WeakPolarHBondContact O-CB 3.42Å; F133-S137 PolarHBondContact O-N 2.66Å; F133-S137 PolarHBondContact O-OG 3.28Å; F135-S137 VanDerWaalsContact C-N 3.26Å; F135-S137 PolarHBondContact O-N 2.84Å; S137-T141 WeakPolarHBondContact O-CB 3.45Å; S137-T141 PolarHBondContact O-N 3.42Å; S137-T141 PolarHBondContact O-OG1 3.38Å
138	W	77.5	Confident	74.1	Confident	2 Å²	2	42 Å²	42	1%	0.008	23%	0.225	C	C	.	.	H	α-helix	trans	-63.8	-46	173.8	-88.4	120	0	0	0	112.6	I54 I58 I122 I134 F135 I136 L140 T141 I142 L238 Y242	I54-W138 HydrophobicContact CB-CZ3 4.47Å; I54-W138 HydrophobicContact CG1-CE3 4.41Å; I54-W138 HydrophobicContact CG1-CH2 4.34Å; I54-W138 HydrophobicContact CG1-CZ3 3.84Å; I54-W138 HydrophobicContact CG2-CD2 4.36Å; I54-W138 HydrophobicContact CG2-CE3 3.96Å; I54-W138 HydrophobicContact CG2-CZ3 4.11Å; I58-W138 HydrophobicContact CD1-CB 4.4Å; I58-W138 HydrophobicContact CD1-CD2 4.41Å; I58-W138 HydrophobicContact CD1-CG 4.06Å; I58-W138 HydrophobicContact CG1-CD2 4.36Å; I58-W138 HydrophobicContact CG1-CG 4.13Å; I122-W138 HydrophobicContact CD1-CH2 3.95Å; I122-W138 HydrophobicContact CD1-CZ2 3.92Å; I122-W138 HydrophobicContact CG1-CZ2 4.5Å; I122-W138 HydrophobicContact CG2-CZ2 3.61Å; I134-W138 VanDerWaalsContact O-CD1 3.3Å; I134-W138 PolarHBondContact O-N 2.92Å; I134-W138 VanDerWaalsContact O-N 3.11Å; F135-W138 PolarHBondContact O-N 3.46Å; I136-W138 VanDerWaalsContact C-N 3.33Å; I136-W138 PolarHBondContact O-N 3.25Å; W138-L140 PolarHBondContact O-N 2.89Å; W138-T141 HydrophobicContact CE3-CG2 4.42Å; W138-T141 HydrophobicContact CZ3-CG2 4.39Å; W138-T141 WeakPolarHBondContact O-CB 3.49Å; W138-T141 PolarHBondContact O-N 2.88Å; W138-I142 WeakPolarHBondContact O-CD1 3.43Å; W138-I142 WeakPolarHBondContact O-CG1 3.48Å; W138-I142 PolarHBondContact O-N 3.42Å; W138-L238 HydrophobicContact CZ3-CD2 4.1Å; W138-L238 HydrophobicContact CZ3-CG 4.23Å; W138-Y242 HydrophobicContact CB-CE2 4.2Å; W138-Y242 AromaticContact CD1-CE2 3.25Å; W138-Y242 AromaticContact CD1-CZ 3.6Å; W138-Y242 AromaticContact CD2-CD2 3.55Å; W138-Y242 HydrophobicContact CD2-CD2 3.55Å; W138-Y242 AromaticContact CD2-CE2 3.58Å; W138-Y242 HydrophobicContact CD2-CE2 3.58Å; W138-Y242 HydrophobicContact CD2-CG 4.24Å; W138-Y242 AromaticContact CE2-CD2 3.66Å; W138-Y242 AromaticContact CE2-CE2 3.51Å; W138-Y242 AromaticContact CE2-CZ 3.71Å; W138-Y242 AromaticContact CE3-CD2 3.92Å; W138-Y242 HydrophobicContact CE3-CD2 3.92Å; W138-Y242 HydrophobicContact CE3-CE2 4.4Å; W138-Y242 HydrophobicContact CE3-CG 4.41Å; W138-Y242 AromaticContact CG-CD2 3.83Å; W138-Y242 HydrophobicContact CG-CD2 3.83Å; W138-Y242 AromaticContact CG-CE2 3.44Å; W138-Y242 HydrophobicContact CG-CE2 3.44Å; W138-Y242 VanDerWaalsContact CG-CE2 3.44Å; W138-Y242 HydrophobicContact CH2-CD2 4.46Å; W138-Y242 HydrophobicContact CH2-CG 4.22Å; W138-Y242 HydrophobicContact CZ2-CD1 4.11Å; W138-Y242 HydrophobicContact CZ2-CD2 4.15Å; W138-Y242 HydrophobicContact CZ2-CE1 4.23Å; W138-Y242 HydrophobicContact CZ2-CE2 4.29Å; W138-Y242 HydrophobicContact CZ2-CG 4.04Å; W138-Y242 HydrophobicContact CZ3-CD2 4.34Å; W138-Y242 HydrophobicContact CZ3-CG 4.38Å; W138-Y242 AromaticContact NE1-CD2 3.94Å; W138-Y242 AromaticContact NE1-CE1 3.93Å; W138-Y242 AromaticContact NE1-CE2 3.28Å; W138-Y242 VanDerWaalsContact NE1-CE2 3.28Å; W138-Y242 AromaticContact NE1-CZ 3.24Å; W138-Y242 PolarHBondContact NE1-OH 2.91Å
139	I	76.3	Confident	75.2	Confident	58 Å²	58	41.6 Å²	41.6	30%	0.297	22%	0.222	S	C	.	.	H	α-helix	trans	-59.6	-49.1	177.8	-70.2	166.3	0	0	0	110.3	F135 I136 T141 I142 I143 F267 I271	F135-I139 WeakPolarHBondContact O-CG1 3.11Å; F135-I139 PolarHBondContact O-N 2.8Å; I136-I139 PolarHBondContact O-N 3.02Å; I139-T141 VanDerWaalsContact C-N 3.31Å; I139-T141 PolarHBondContact O-N 2.93Å; I139-I142 PolarHBondContact O-N 3.21Å; I139-I143 HydrophobicContact CG2-CD1 3.64Å; I139-I143 HydrophobicContact CG2-CG1 4.4Å; I139-I143 WeakPolarHBondContact O-CB 3.23Å; I139-I143 VanDerWaalsContact O-CG1 3.28Å; I139-I143 WeakPolarHBondContact O-CG1 3.46Å; I139-I143 PolarHBondContact O-N 3.35Å; I139-F267 HydrophobicContact CD1-CE1 3.86Å; I139-F267 HydrophobicContact CD1-CZ 3.45Å; I139-F267 VanDerWaalsContact CD1-CZ 3.45Å; I139-I271 HydrophobicContact CD1-CD1 3.9Å; I139-I271 HydrophobicContact CG1-CD1 4.22Å
140	L	81.3	Confident	76.3	Confident	72 Å²	72	45.6 Å²	45.6	38%	0.377	24%	0.242	S	C	.	.	H	α-helix	trans	-61.1	-41.1	177.5	-70.7	174.5	0	0	0	111.5	I136 W138 L144 F245	I136-L140 HydrophobicContact CG2-CD1 3.83Å; I136-L140 HydrophobicContact CG2-CG 4.21Å; I136-L140 WeakPolarHBondContact O-CB 3.11Å; I136-L140 VanDerWaalsContact O-CG 3.28Å; I136-L140 WeakPolarHBondContact O-CG 3.41Å; I136-L140 PolarHBondContact O-N 2.87Å; W138-L140 PolarHBondContact O-N 2.89Å; L140-L144 WeakPolarHBondContact O-CB 3.42Å; L140-L144 PolarHBondContact O-N 3.48Å; L140-F245 HydrophobicContact CB-CD1 4.08Å; L140-F245 HydrophobicContact CB-CD2 4.2Å; L140-F245 HydrophobicContact CB-CE1 3.87Å; L140-F245 HydrophobicContact CB-CE2 3.99Å; L140-F245 HydrophobicContact CB-CG 4.24Å; L140-F245 HydrophobicContact CB-CZ 3.82Å; L140-F245 HydrophobicContact CD1-CD1 3.88Å; L140-F245 HydrophobicContact CD1-CE1 3.96Å; L140-F245 HydrophobicContact CG-CE1 4.47Å
141	T	84.8	Confident	77.4	Confident	0 Å²	0	41.3 Å²	41.3	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-61.8	-45.7	176.8	-64	0	0	0	0	112	S137 W138 I139 S145 L238 Y242 F245	S137-T141 WeakPolarHBondContact O-CB 3.45Å; S137-T141 PolarHBondContact O-N 3.42Å; S137-T141 PolarHBondContact O-OG1 3.38Å; W138-T141 HydrophobicContact CE3-CG2 4.42Å; W138-T141 HydrophobicContact CZ3-CG2 4.39Å; W138-T141 WeakPolarHBondContact O-CB 3.49Å; W138-T141 PolarHBondContact O-N 2.88Å; I139-T141 VanDerWaalsContact C-N 3.31Å; I139-T141 PolarHBondContact O-N 2.93Å; T141-S145 VanDerWaalsContact O-CB 3.24Å; T141-S145 WeakPolarHBondContact O-CB 3.29Å; T141-S145 PolarHBondContact O-N 3.42Å; T141-L238 HydrophobicContact CG2-CD1 3.56Å; T141-L238 HydrophobicContact CG2-CG 3.95Å; T141-L238 WeakPolarHBondContact CG2-O 3.49Å; T141-Y242 VanDerWaalsContact OG1-CA 3.28Å; T141-Y242 WeakPolarHBondContact OG1-CA 3.37Å; T141-Y242 PolarHBondContact OG1-N 3.31Å; T141-F245 WeakPolarHBondContact OG1-CD2 3.14Å
142	I	81.5	Confident	78.3	Confident	51 Å²	51	39.9 Å²	39.9	26%	0.262	21%	0.213	S	C	.	.	H	α-helix	trans	-65.2	-49.3	179.1	-67.6	163.1	0	0	0	110.2	I54 W138 I139 L144 S145 V146 I275	I54-I142 HydrophobicContact CD1-CD1 4.43Å; I54-I142 HydrophobicContact CD1-CG1 4.07Å; I54-I142 HydrophobicContact CG2-CD1 4.2Å; W138-I142 WeakPolarHBondContact O-CD1 3.43Å; W138-I142 WeakPolarHBondContact O-CG1 3.48Å; W138-I142 PolarHBondContact O-N 3.42Å; I139-I142 PolarHBondContact O-N 3.21Å; I142-L144 VanDerWaalsContact C-N 3.34Å; I142-L144 PolarHBondContact O-N 2.86Å; I142-S145 PolarHBondContact O-N 3.17Å; I142-V146 WeakPolarHBondContact O-CG2 3.35Å; I142-V146 PolarHBondContact O-N 3.44Å; I142-I275 HydrophobicContact CD1-CD1 4.39Å
143	I	81.8	Confident	79	Confident	89 Å²	89	39.5 Å²	39.5	46%	0.456	21%	0.211	S	C	.	.	H	α-helix	trans	-59	-48.6	178.6	-69.1	170.4	0	0	0	109.9	I139 S145 V146 L147	I139-I143 HydrophobicContact CG2-CD1 3.64Å; I139-I143 HydrophobicContact CG2-CG1 4.4Å; I139-I143 WeakPolarHBondContact O-CB 3.23Å; I139-I143 VanDerWaalsContact O-CG1 3.28Å; I139-I143 WeakPolarHBondContact O-CG1 3.46Å; I139-I143 PolarHBondContact O-N 3.35Å; I143-S145 PolarHBondContact O-N 3.13Å; I143-V146 PolarHBondContact O-N 2.66Å; I143-L147 HydrophobicContact CG2-CD1 3.67Å; I143-L147 HydrophobicContact CG2-CG 4.27Å; I143-L147 WeakPolarHBondContact O-CB 3.29Å; I143-L147 VanDerWaalsContact O-CG 3.25Å; I143-L147 WeakPolarHBondContact O-CG 3.4Å; I143-L147 PolarHBondContact O-N 2.99Å
144	L	85.7	Confident	79.5	Confident	37 Å²	37	43.8 Å²	43.8	19%	0.194	24%	0.236	C	C	.	.	H	α-helix	trans	-60.7	-45.7	178.6	-177.1	64.5	0	0	0	111.1	L140 I142 V146 L147 L148 L200 F245	L140-L144 WeakPolarHBondContact O-CB 3.42Å; L140-L144 PolarHBondContact O-N 3.48Å; I142-L144 VanDerWaalsContact C-N 3.34Å; I142-L144 PolarHBondContact O-N 2.86Å; L144-V146 PolarHBondContact O-N 3.19Å; L144-L147 PolarHBondContact O-N 3.25Å; L144-L148 HydrophobicContact CD1-CD1 3.83Å; L144-L148 HydrophobicContact CD1-CD2 4.39Å; L144-L148 HydrophobicContact CD1-CG 3.9Å; L144-L148 HydrophobicContact CD2-CD1 4.3Å; L144-L148 HydrophobicContact CG-CD1 3.69Å; L144-L148 HydrophobicContact CG-CG 4.16Å; L144-L148 WeakPolarHBondContact O-CB 3.14Å; L144-L148 WeakPolarHBondContact O-CG 3.39Å; L144-L148 PolarHBondContact O-N 3.31Å; L144-L200 HydrophobicContact CD2-CD2 4.09Å; L144-F245 HydrophobicContact CB-CE2 4.4Å; L144-F245 HydrophobicContact CD2-CE2 3.77Å; L144-F245 HydrophobicContact CD2-CZ 3.85Å
145	S	84.9	Confident	79.6	Confident	29 Å²	29	46.1 Å²	46.1	20%	0.203	25%	0.247	C	C	.	.	H	α-helix	trans	-61.3	-43.7	179.3	-178.5	0	0	0	0	112.2	T141 I142 I143 F149	T141-S145 VanDerWaalsContact O-CB 3.24Å; T141-S145 WeakPolarHBondContact O-CB 3.29Å; T141-S145 PolarHBondContact O-N 3.42Å; I142-S145 PolarHBondContact O-N 3.17Å; I143-S145 PolarHBondContact O-N 3.13Å; S145-F149 VanDerWaalsContact O-CB 3.27Å; S145-F149 WeakPolarHBondContact O-CB 3.43Å; S145-F149 PolarHBondContact O-N 3.17Å
146	V	82.9	Confident	79.8	Confident	69 Å²	69	54.2 Å²	54.2	42%	0.418	29%	0.285	S	S	.	.	H	α-helix	trans	-67.2	-44.8	178.1	172.8	0	0	0	0	110.7	I142 I143 L144 F149 L150	I142-V146 WeakPolarHBondContact O-CG2 3.35Å; I142-V146 PolarHBondContact O-N 3.44Å; I143-V146 PolarHBondContact O-N 2.66Å; L144-V146 PolarHBondContact O-N 3.19Å; V146-F149 PolarHBondContact O-N 3.45Å; V146-L150 HydrophobicContact CG1-CD1 4Å; V146-L150 HydrophobicContact CG1-CG 4.45Å; V146-L150 WeakPolarHBondContact O-CG 2.84Å; V146-L150 PolarHBondContact O-N 3.43Å
147	L	84.1	Confident	79.8	Confident	95 Å²	95	60.9 Å²	60.9	50%	0.497	31%	0.307	S	S	.	.	H	α-helix	trans	-61.7	-49.1	178.2	-74.2	173.7	0	0	0	111.7	I143 L144 F149 L150 V151	I143-L147 HydrophobicContact CG2-CD1 3.67Å; I143-L147 HydrophobicContact CG2-CG 4.27Å; I143-L147 WeakPolarHBondContact O-CB 3.29Å; I143-L147 VanDerWaalsContact O-CG 3.25Å; I143-L147 WeakPolarHBondContact O-CG 3.4Å; I143-L147 PolarHBondContact O-N 2.99Å; L144-L147 PolarHBondContact O-N 3.25Å; L147-F149 VanDerWaalsContact C-N 3.28Å; L147-F149 PolarHBondContact O-N 3.11Å; L147-L150 PolarHBondContact O-N 3.22Å; L147-V151 WeakPolarHBondContact O-CB 3.22Å; L147-V151 VanDerWaalsContact O-CG2 3.24Å; L147-V151 WeakPolarHBondContact O-CG2 3.4Å; L147-V151 PolarHBondContact O-N 2.82Å
148	L	85.8	Confident	79.7	Confident	18 Å²	18	62.3 Å²	62.3	9%	0.094	31%	0.314	C	S	.	.	H	α-helix	trans	-62.3	-38.4	178.2	-68.6	174.8	0	0	0	111.2	L144 G152 I204 L208	L144-L148 HydrophobicContact CD1-CD1 3.83Å; L144-L148 HydrophobicContact CD1-CD2 4.39Å; L144-L148 HydrophobicContact CD1-CG 3.9Å; L144-L148 HydrophobicContact CD2-CD1 4.3Å; L144-L148 HydrophobicContact CG-CD1 3.69Å; L144-L148 HydrophobicContact CG-CG 4.16Å; L144-L148 WeakPolarHBondContact O-CB 3.14Å; L144-L148 WeakPolarHBondContact O-CG 3.39Å; L144-L148 PolarHBondContact O-N 3.31Å; L148-G152 PolarHBondContact O-N 3.46Å; L148-I204 HydrophobicContact CD1-CG1 4.21Å; L148-I204 HydrophobicContact CD2-CB 4.48Å; L148-I204 HydrophobicContact CD2-CG1 4.48Å; L148-I204 HydrophobicContact CD2-CG2 3.93Å; L148-L208 HydrophobicContact CD2-CD2 4.22Å; L148-L208 HydrophobicContact CD2-CG 4.23Å; L148-L208 WeakPolarHBondContact O-CD2 3.32Å
149	F	82.3	Confident	79.5	Confident	25 Å²	25	64.2 Å²	64.2	11%	0.11	32%	0.324	C	S	.	.	H	α-helix	trans	-63.5	-48.3	176	-172.6	-103.5	0	0	0	112.4	I43 F47 S145 V146 L147 G152 I153 A211 L214	I43-F149 HydrophobicContact CG2-CE1 4.18Å; I43-F149 HydrophobicContact CG2-CZ 3.76Å; F47-F149 AromaticContact CE2-CD1 3.83Å; F47-F149 HydrophobicContact CE2-CD1 3.83Å; F47-F149 HydrophobicContact CE2-CD2 4.11Å; F47-F149 AromaticContact CE2-CE1 3.43Å; F47-F149 HydrophobicContact CE2-CE1 3.43Å; F47-F149 VanDerWaalsContact CE2-CE1 3.43Å; F47-F149 AromaticContact CE2-CE2 3.78Å; F47-F149 HydrophobicContact CE2-CE2 3.78Å; F47-F149 HydrophobicContact CE2-CG 4.14Å; F47-F149 AromaticContact CE2-CZ 3.42Å; F47-F149 HydrophobicContact CE2-CZ 3.42Å; F47-F149 VanDerWaalsContact CE2-CZ 3.42Å; F47-F149 HydrophobicContact CZ-CB 4.21Å; F47-F149 AromaticContact CZ-CD1 3.52Å; F47-F149 HydrophobicContact CZ-CD1 3.52Å; F47-F149 AromaticContact CZ-CD2 3.61Å; F47-F149 HydrophobicContact CZ-CD2 3.61Å; F47-F149 AromaticContact CZ-CE1 3.65Å; F47-F149 HydrophobicContact CZ-CE1 3.65Å; F47-F149 AromaticContact CZ-CE2 3.78Å; F47-F149 HydrophobicContact CZ-CE2 3.78Å; F47-F149 AromaticContact CZ-CG 3.49Å; F47-F149 HydrophobicContact CZ-CG 3.49Å; F47-F149 VanDerWaalsContact CZ-CG 3.49Å; F47-F149 AromaticContact CZ-CZ 3.79Å; F47-F149 HydrophobicContact CZ-CZ 3.79Å; S145-F149 VanDerWaalsContact O-CB 3.27Å; S145-F149 WeakPolarHBondContact O-CB 3.43Å; S145-F149 PolarHBondContact O-N 3.17Å; V146-F149 PolarHBondContact O-N 3.45Å; L147-F149 VanDerWaalsContact C-N 3.28Å; L147-F149 PolarHBondContact O-N 3.11Å; F149-G152 PolarHBondContact O-N 2.96Å; F149-I153 HydrophobicContact CD1-CD1 3.81Å; F149-I153 HydrophobicContact CE1-CD1 3.24Å; F149-I153 HydrophobicContact CE1-CG1 4.38Å; F149-I153 HydrophobicContact CE2-CD1 4.18Å; F149-I153 HydrophobicContact CG-CD1 4.49Å; F149-I153 HydrophobicContact CZ-CD1 3.45Å; F149-I153 VanDerWaalsContact CZ-CD1 3.45Å; F149-I153 HydrophobicContact CZ-CG1 4.35Å; F149-I153 WeakPolarHBondContact O-CG1 3.42Å; F149-I153 PolarHBondContact O-N 2.9Å; F149-I153 VanDerWaalsContact O-N 3.13Å; F149-A211 HydrophobicContact CD2-CB 3.46Å; F149-A211 VanDerWaalsContact CD2-CB 3.46Å; F149-A211 HydrophobicContact CE2-CB 3.89Å; F149-A211 HydrophobicContact CG-CB 4.21Å; F149-L214 HydrophobicContact CE2-CB 4.23Å; F149-L214 HydrophobicContact CE2-CD1 3.65Å; F149-L214 HydrophobicContact CZ-CD1 4.21Å
150	L	81.6	Confident	79.2	Confident	93 Å²	93	61.5 Å²	61.5	49%	0.487	31%	0.31	S	S	.	.	H	α-helix	trans	-62.5	-43.1	177.7	-70.9	173.6	0	0	0	112.3	V146 L147 N154	V146-L150 HydrophobicContact CG1-CD1 4Å; V146-L150 HydrophobicContact CG1-CG 4.45Å; V146-L150 WeakPolarHBondContact O-CG 2.84Å; V146-L150 PolarHBondContact O-N 3.43Å; L147-L150 PolarHBondContact O-N 3.22Å; L150-N154 WeakPolarHBondContact O-CB 3.41Å; L150-N154 VanDerWaalsContact O-CG 3.29Å; L150-N154 PolarHBondContact O-N 3.48Å; L150-N154 PolarHBondContact O-ND2 3.22Å; L150-N154 VanDerWaalsContact O-ND2 3.14Å
151	V	81.1	Confident	78.8	Confident	75 Å²	75	60.4 Å²	60.4	46%	0.455	31%	0.309	S	S	.	.	H	α-helix	trans	-64.7	-45.5	176.9	172.3	0	0	0	0	110.2	L147 I153 N154 I155 L208	L147-V151 WeakPolarHBondContact O-CB 3.22Å; L147-V151 VanDerWaalsContact O-CG2 3.24Å; L147-V151 WeakPolarHBondContact O-CG2 3.4Å; L147-V151 PolarHBondContact O-N 2.82Å; V151-I153 VanDerWaalsContact C-N 3.32Å; V151-I153 PolarHBondContact O-N 2.93Å; V151-N154 PolarHBondContact O-N 2.9Å; V151-I155 HydrophobicContact CG1-CD1 4.03Å; V151-I155 HydrophobicContact CG1-CG1 4.34Å; V151-I155 WeakPolarHBondContact O-CG1 3.5Å; V151-I155 PolarHBondContact O-N 3.39Å; V151-I155 VanDerWaalsContact O-N 3.09Å; V151-L208 HydrophobicContact CB-CD2 4.05Å; V151-L208 HydrophobicContact CG1-CD2 3.8Å
152	G	78.2	Confident	78.3	Confident	0 Å²	0	66.8 Å²	66.8	0%	0	33%	0.334	C	S	.	.	H	α-helix	trans	-57.8	-42.6	-179.4	0	0	0	0	0	113	L148 F149 N154 I155 Q212	L148-G152 PolarHBondContact O-N 3.46Å; F149-G152 PolarHBondContact O-N 2.96Å; G152-N154 VanDerWaalsContact C-N 3.32Å; G152-N154 PolarHBondContact O-N 3.19Å; G152-I155 PolarHBondContact O-N 3.42Å; G152-Q212 WeakPolarHBondContact O-CG 3.27Å; G152-Q212 PolarHBondContact O-NE2 3.48Å
153	I	78.3	Confident	77.8	Confident	26 Å²	26	66.6 Å²	66.6	13%	0.133	33%	0.332	C	S	.	.	H	α-helix	trans	-64.5	-36.5	175.2	-67.6	175.5	0	0	0	112.2	L31 F149 V151 Y215	L31-I153 WeakPolarHBondContact CD2-O 3.14Å; F149-I153 HydrophobicContact CD1-CD1 3.81Å; F149-I153 HydrophobicContact CE1-CD1 3.24Å; F149-I153 HydrophobicContact CE1-CG1 4.38Å; F149-I153 HydrophobicContact CE2-CD1 4.18Å; F149-I153 HydrophobicContact CG-CD1 4.49Å; F149-I153 HydrophobicContact CZ-CD1 3.45Å; F149-I153 VanDerWaalsContact CZ-CD1 3.45Å; F149-I153 HydrophobicContact CZ-CG1 4.35Å; F149-I153 WeakPolarHBondContact O-CG1 3.42Å; F149-I153 PolarHBondContact O-N 2.9Å; F149-I153 VanDerWaalsContact O-N 3.13Å; V151-I153 VanDerWaalsContact C-N 3.32Å; V151-I153 PolarHBondContact O-N 2.93Å; I153-Y215 HydrophobicContact CB-CG 4.44Å; I153-Y215 HydrophobicContact CD1-CD2 3.71Å; I153-Y215 HydrophobicContact CD1-CE2 4.38Å; I153-Y215 HydrophobicContact CD1-CG 4.19Å; I153-Y215 HydrophobicContact CG1-CD2 3.97Å; I153-Y215 HydrophobicContact CG1-CG 3.94Å; I153-Y215 HydrophobicContact CG2-CD1 3.91Å; I153-Y215 HydrophobicContact CG2-CD2 3.76Å; I153-Y215 HydrophobicContact CG2-CE1 3.91Å; I153-Y215 HydrophobicContact CG2-CE2 3.78Å; I153-Y215 HydrophobicContact CG2-CG 3.82Å
154	N	75.2	Confident	77.4	Confident	124 Å²	124	72.5 Å²	72.5	66%	0.663	35%	0.348	S	S	*	.	H	α-helix	trans	-82.7	-10.7	-175.6	-73	-26	0	0	0	113.9	L150 V151 G152 E156	L150-N154 WeakPolarHBondContact O-CB 3.41Å; L150-N154 VanDerWaalsContact O-CG 3.29Å; L150-N154 PolarHBondContact O-N 3.48Å; L150-N154 PolarHBondContact O-ND2 3.22Å; L150-N154 VanDerWaalsContact O-ND2 3.14Å; V151-N154 PolarHBondContact O-N 2.9Å; G152-N154 VanDerWaalsContact C-N 3.32Å; G152-N154 PolarHBondContact O-N 3.19Å; N154-E156 PolarHBondContact O-N 3.25Å
155	I	72.4	Confident	77	Confident	49 Å²	49	79.6 Å²	79.6	25%	0.251	37%	0.372	S	S	.	.			trans	-73.1	117.1	176.3	-69.4	165.7	0	0	0	109.1	V151 G152 R157 L159 L208 Q212	V151-I155 HydrophobicContact CG1-CD1 4.03Å; V151-I155 HydrophobicContact CG1-CG1 4.34Å; V151-I155 WeakPolarHBondContact O-CG1 3.5Å; V151-I155 PolarHBondContact O-N 3.39Å; V151-I155 VanDerWaalsContact O-N 3.09Å; G152-I155 PolarHBondContact O-N 3.42Å; I155-R157 VanDerWaalsContact C-N 3.28Å; I155-R157 HydrophobicContact CG2-CB 4.12Å; I155-R157 WeakPolarHBondContact CG2-O 3.31Å; I155-R157 PolarHBondContact O-N 3.46Å; I155-L159 HydrophobicContact CD1-CD1 3.86Å; I155-L159 HydrophobicContact CG2-CD1 4.4Å; I155-L159 HydrophobicContact CG2-CG 4.28Å; I155-L208 HydrophobicContact CD1-CD2 4.19Å; I155-Q212 PolarHBondContact O-NE2 3.39Å
156	E	71	Confident	76.7	Confident	170 Å²	170	79.2 Å²	79.2	79%	0.794	37%	0.367	S	S	*	.			trans	-68.7	-25.3	-179.9	-62.6	-176.4	164.3	0	0	113.6	N154	N154-E156 PolarHBondContact O-N 3.25Å
157	R	72	Confident	76.4	Confident	196 Å²	196	80.4 Å²	80.4	74%	0.74	37%	0.369	S	S	*	.	S	Bend	trans	-78.1	138.3	177.5	-69.1	-174.3	179.1	-177.4	0.3	110.7	I155 L159 Q212	I155-R157 VanDerWaalsContact C-N 3.28Å; I155-R157 HydrophobicContact CG2-CB 4.12Å; I155-R157 WeakPolarHBondContact CG2-O 3.31Å; I155-R157 PolarHBondContact O-N 3.46Å; R157-L159 PolarHBondContact O-N 2.89Å; R157-Q212 PolarHBondContact O-NE2 3.31Å
158	D	75.1	Confident	76.2	Confident	30 Å²	30	80.9 Å²	80.9	16%	0.16	37%	0.371	C	S	.	.			trans	-76.7	93.8	175.5	-167.9	25.9	0	0	0	110.6	V160 S161 R218 E219	D158-V160 PolarHBondContact O-N 2.68Å; D158-V160 VanDerWaalsContact OD1-CB 3.3Å; D158-V160 WeakPolarHBondContact OD1-CB 3.27Å; D158-V160 WeakPolarHBondContact OD1-CG2 3.23Å; D158-S161 PolarHBondContact O-N 3.34Å; D158-S161 PolarHBondContact O-OG 3.46Å; D158-R218 WeakPolarHBondContact OD2-CB 3.26Å; D158-E219 PolarHBondContact OD2-N 3.49Å
159	L	72.2	Confident	76	Confident	42 Å²	42	84.5 Å²	84.5	22%	0.22	38%	0.384	C	S	.	.	G	3₁₀ helix	trans	-65.6	-24.5	177.3	-60.7	172.1	0	0	0	111.4	I155 R157 S161 Y162 L208 I209	I155-L159 HydrophobicContact CD1-CD1 3.86Å; I155-L159 HydrophobicContact CG2-CD1 4.4Å; I155-L159 HydrophobicContact CG2-CG 4.28Å; R157-L159 PolarHBondContact O-N 2.89Å; L159-S161 PolarHBondContact O-N 3.33Å; L159-Y162 PolarHBondContact O-N 3.34Å; L159-L208 HydrophobicContact CD1-CB 3.96Å; L159-I209 HydrophobicContact CB-CG1 3.95Å
160	V	71.4	Confident	75.7	Confident	1 Å²	1	84.8 Å²	84.8	1%	0.006	39%	0.387	C	S	.	.	G	3₁₀ helix	trans	-59	-32.4	179.1	-174.2	0	0	0	0	111.7	D158 Y162 F163 Q212 I213 E219 M220	D158-V160 PolarHBondContact O-N 2.68Å; D158-V160 VanDerWaalsContact OD1-CB 3.3Å; D158-V160 WeakPolarHBondContact OD1-CB 3.27Å; D158-V160 WeakPolarHBondContact OD1-CG2 3.23Å; V160-Y162 PolarHBondContact O-N 3.27Å; V160-F163 WeakPolarHBondContact O-CB 3.36Å; V160-F163 PolarHBondContact O-N 2.96Å; V160-Q212 HydrophobicContact CG2-CB 4.01Å; V160-I213 HydrophobicContact CG1-CG1 4.41Å; V160-I213 HydrophobicContact CG2-CG1 3.93Å; V160-E219 HydrophobicContact CG1-CB 4.11Å; V160-M220 HydrophobicContact CG1-CB 3.54Å; V160-M220 HydrophobicContact CG1-CE 3.3Å; V160-M220 HydrophobicContact CG1-CG 3.62Å; V160-M220 HydrophobicContact CG1-SD 4.3Å
161	S	71.8	Confident	75.5	Confident	50 Å²	50	83.1 Å²	83.1	35%	0.35	39%	0.386	S	S	.	.	G	3₁₀ helix	trans	-60.5	-26	174.9	66.1	0	0	0	0	113.8	D158 L159 F163 E219	D158-S161 PolarHBondContact O-N 3.34Å; D158-S161 PolarHBondContact O-OG 3.46Å; L159-S161 PolarHBondContact O-N 3.33Å; S161-F163 VanDerWaalsContact C-N 3.32Å; S161-E219 WeakPolarHBondContact CA-OE2 3.4Å
162	Y	75.3	Confident	75.7	Confident	133 Å²	133	82.2 Å²	82.2	52%	0.522	38%	0.383	S	S	.	.	G	3₁₀ helix	trans	-89.9	6.4	178	-59.3	-85.1	0	0	0	113	L159 V160 R164 W165 F166	L159-Y162 PolarHBondContact O-N 3.34Å; V160-Y162 PolarHBondContact O-N 3.27Å; Y162-R164 PolarHBondContact O-N 2.87Å; Y162-R164 VanDerWaalsContact O-N 3.1Å; Y162-W165 WeakPolarHBondContact O-CB 3.45Å; Y162-W165 PolarHBondContact O-N 2.75Å; Y162-F166 PolarHBondContact O-N 2.93Å
163	F	71.1	Confident	75.8	Confident	48 Å²	48	83 Å²	83	21%	0.211	39%	0.387	C	S	.	.	H	α-helix	trans	-54	-37.3	-174	-173.2	-98.5	0	0	0	113.6	V160 S161 F166 M167 I209 M220	V160-F163 WeakPolarHBondContact O-CB 3.36Å; V160-F163 PolarHBondContact O-N 2.96Å; S161-F163 VanDerWaalsContact C-N 3.32Å; F163-F166 WeakPolarHBondContact O-CB 3.31Å; F163-F166 PolarHBondContact O-N 3.31Å; F163-M167 HydrophobicContact CD1-CG 4.12Å; F163-M167 HydrophobicContact CE1-CG 3.81Å; F163-M167 HydrophobicContact CE1-SD 4.16Å; F163-M167 HydrophobicContact CZ-CG 4.21Å; F163-M167 HydrophobicContact CZ-SD 3.99Å; F163-M167 WeakPolarHBondContact O-CG 3.46Å; F163-M167 PolarHBondContact O-N 3.44Å; F163-I209 HydrophobicContact CD2-CG2 4.11Å; F163-M220 HydrophobicContact CB-CE 3.45Å; F163-M220 VanDerWaalsContact CB-CE 3.45Å; F163-M220 HydrophobicContact CD1-CE 3.82Å; F163-M220 HydrophobicContact CD2-CE 3.76Å; F163-M220 HydrophobicContact CE1-CE 4.48Å; F163-M220 HydrophobicContact CE2-CE 4.42Å; F163-M220 HydrophobicContact CG-CE 3.41Å; F163-M220 VanDerWaalsContact CG-CE 3.41Å
164	R	73.9	Confident	75.9	Confident	212 Å²	212	85.5 Å²	85.5	80%	0.8	40%	0.4	S	S	*	.	H	α-helix	trans	-64	-43.9	176.9	-64.3	-178.2	78.9	-169.4	5.6	112.3	Y162 F166 M167 I168	Y162-R164 PolarHBondContact O-N 2.87Å; Y162-R164 VanDerWaalsContact O-N 3.1Å; R164-F166 VanDerWaalsContact C-N 3.29Å; R164-M167 PolarHBondContact O-N 3.32Å; R164-I168 WeakPolarHBondContact O-CG1 3.44Å; R164-I168 PolarHBondContact O-N 2.96Å
165	W	76.9	Confident	76.2	Confident	186 Å²	186	84.6 Å²	84.6	71%	0.705	40%	0.395	S	S	*	.	H	α-helix	trans	-66.7	-36	175.6	-67.5	110.9	0	0	0	111.4	Y162 I168 Y169	Y162-W165 WeakPolarHBondContact O-CB 3.45Å; Y162-W165 PolarHBondContact O-N 2.75Å; W165-I168 HydrophobicContact CE3-CD1 4.07Å; W165-I168 HydrophobicContact CZ3-CD1 4.32Å; W165-I168 PolarHBondContact O-N 3.11Å; W165-Y169 PolarHBondContact O-N 2.92Å
166	F	78.4	Confident	76.8	Confident	21 Å²	21	85.4 Å²	85.4	9%	0.092	40%	0.402	C	S	.	.	H	α-helix	trans	-62.7	-42.7	175.1	-178.3	-116.8	0	0	0	112.6	Y162 F163 R164 I168 Y169 I170 P205 A206 I209	Y162-F166 PolarHBondContact O-N 2.93Å; F163-F166 WeakPolarHBondContact O-CB 3.31Å; F163-F166 PolarHBondContact O-N 3.31Å; R164-F166 VanDerWaalsContact C-N 3.29Å; F166-I168 VanDerWaalsContact C-N 3.3Å; F166-I168 PolarHBondContact O-N 2.86Å; F166-Y169 HydrophobicContact CD2-CD1 4.1Å; F166-Y169 AromaticContact CE2-CD1 3.95Å; F166-Y169 HydrophobicContact CE2-CD1 3.95Å; F166-Y169 HydrophobicContact CE2-CE1 4.41Å; F166-Y169 WeakPolarHBondContact O-CB 3.43Å; F166-Y169 PolarHBondContact O-N 3.37Å; F166-Y169 VanDerWaalsContact O-N 3.13Å; F166-I170 HydrophobicContact CD1-CD1 3.73Å; F166-I170 HydrophobicContact CD1-CG1 4.42Å; F166-I170 HydrophobicContact CD2-CG1 4.43Å; F166-I170 HydrophobicContact CE1-CD1 3.14Å; F166-I170 HydrophobicContact CE1-CG1 3.92Å; F166-I170 HydrophobicContact CE2-CD1 4.02Å; F166-I170 HydrophobicContact CE2-CG1 3.84Å; F166-I170 HydrophobicContact CG-CD1 4.4Å; F166-I170 HydrophobicContact CZ-CD1 3.29Å; F166-I170 HydrophobicContact CZ-CG1 3.57Å; F166-I170 WeakPolarHBondContact O-CG1 3.19Å; F166-I170 PolarHBondContact O-N 2.94Å; F166-P205 HydrophobicContact CD2-CB 4.05Å; F166-P205 HydrophobicContact CD2-CG 4.41Å; F166-P205 HydrophobicContact CE2-CB 3.47Å; F166-P205 VanDerWaalsContact CE2-CB 3.47Å; F166-P205 HydrophobicContact CE2-CG 3.51Å; F166-P205 HydrophobicContact CZ-CB 4.18Å; F166-P205 HydrophobicContact CZ-CG 4.2Å; F166-A206 HydrophobicContact CE1-CB 4.01Å; F166-A206 VanDerWaalsContact CZ-CA 3.41Å; F166-A206 HydrophobicContact CZ-CB 3.63Å; F166-A206 VanDerWaalsContact CZ-N 3.33Å; F166-I209 HydrophobicContact CB-CD1 3.85Å; F166-I209 HydrophobicContact CD1-CD1 3.42Å; F166-I209 VanDerWaalsContact CD1-CD1 3.42Å; F166-I209 HydrophobicContact CD2-CD1 3.91Å; F166-I209 HydrophobicContact CE1-CD1 3.92Å; F166-I209 HydrophobicContact CE2-CD1 4.43Å; F166-I209 HydrophobicContact CG-CD1 3.41Å; F166-I209 VanDerWaalsContact CG-CD1 3.41Å; F166-I209 HydrophobicContact CZ-CD1 4.42Å
167	M	75.4	Confident	77.2	Confident	94 Å²	94	78.6 Å²	78.6	46%	0.463	37%	0.371	S	S	.	.	H	α-helix	trans	-61.7	-37.8	174.9	-70.3	-57	-68.9	0	0	112.7	F163 R164 Y169 I170 A171	F163-M167 HydrophobicContact CD1-CG 4.12Å; F163-M167 HydrophobicContact CE1-CG 3.81Å; F163-M167 HydrophobicContact CE1-SD 4.16Å; F163-M167 HydrophobicContact CZ-CG 4.21Å; F163-M167 HydrophobicContact CZ-SD 3.99Å; F163-M167 WeakPolarHBondContact O-CG 3.46Å; F163-M167 PolarHBondContact O-N 3.44Å; R164-M167 PolarHBondContact O-N 3.32Å; M167-Y169 VanDerWaalsContact C-N 3.35Å; M167-I170 PolarHBondContact O-N 2.75Å; M167-I170 HydrophobicContact SD-CD1 4.22Å; M167-A171 WeakPolarHBondContact O-CB 3.12Å; M167-A171 PolarHBondContact O-N 2.68Å
168	I	81.3	Confident	77.5	Confident	105 Å²	105	74 Å²	74	54%	0.538	36%	0.36	S	S	.	.	H	α-helix	trans	-65.1	-41.4	174.6	-64.1	167.7	0	0	0	110.4	R164 W165 F166 A171 S172	R164-I168 WeakPolarHBondContact O-CG1 3.44Å; R164-I168 PolarHBondContact O-N 2.96Å; W165-I168 HydrophobicContact CE3-CD1 4.07Å; W165-I168 HydrophobicContact CZ3-CD1 4.32Å; W165-I168 PolarHBondContact O-N 3.11Å; F166-I168 VanDerWaalsContact C-N 3.3Å; F166-I168 PolarHBondContact O-N 2.86Å; I168-A171 PolarHBondContact O-N 3.35Å; I168-S172 PolarHBondContact O-N 3.19Å; I168-S172 PolarHBondContact O-OG 3.38Å
169	Y	80.5	Confident	77.9	Confident	95 Å²	95	77.3 Å²	77.3	37%	0.373	38%	0.377	S	S	.	.	H	α-helix	trans	-63.4	-43.5	176	170.8	-97.6	0	0	0	112.9	W165 F166 M167 S172 I173 A201 P205	W165-Y169 PolarHBondContact O-N 2.92Å; F166-Y169 HydrophobicContact CD2-CD1 4.1Å; F166-Y169 AromaticContact CE2-CD1 3.95Å; F166-Y169 HydrophobicContact CE2-CD1 3.95Å; F166-Y169 HydrophobicContact CE2-CE1 4.41Å; F166-Y169 WeakPolarHBondContact O-CB 3.43Å; F166-Y169 PolarHBondContact O-N 3.37Å; F166-Y169 VanDerWaalsContact O-N 3.13Å; M167-Y169 VanDerWaalsContact C-N 3.35Å; Y169-S172 PolarHBondContact O-N 3.21Å; Y169-S172 PolarHBondContact O-OG 2.95Å; Y169-I173 HydrophobicContact CD1-CD1 4.21Å; Y169-I173 HydrophobicContact CD2-CD1 4.34Å; Y169-I173 HydrophobicContact CE1-CD1 3.52Å; Y169-I173 HydrophobicContact CE2-CD1 3.67Å; Y169-I173 HydrophobicContact CE2-CG1 4.36Å; Y169-I173 PolarHBondContact O-N 3.21Å; Y169-I173 VanDerWaalsContact O-N 3.13Å; Y169-I173 VanDerWaalsContact OH-CD1 3.3Å; Y169-I173 WeakPolarHBondContact OH-CD1 3.35Å; Y169-A201 PolarHBondContact OH-O 3.39Å; Y169-P205 HydrophobicContact CE1-CG 3.88Å
170	I	76.3	Confident	78.3	Confident	31 Å²	31	77.1 Å²	77.1	16%	0.159	38%	0.376	C	S	.	.	H	α-helix	trans	-61.5	-48	174.9	-65	168.4	0	0	0	110.1	F166 M167 S172 I173 I174 I202	F166-I170 HydrophobicContact CD1-CD1 3.73Å; F166-I170 HydrophobicContact CD1-CG1 4.42Å; F166-I170 HydrophobicContact CD2-CG1 4.43Å; F166-I170 HydrophobicContact CE1-CD1 3.14Å; F166-I170 HydrophobicContact CE1-CG1 3.92Å; F166-I170 HydrophobicContact CE2-CD1 4.02Å; F166-I170 HydrophobicContact CE2-CG1 3.84Å; F166-I170 HydrophobicContact CG-CD1 4.4Å; F166-I170 HydrophobicContact CZ-CD1 3.29Å; F166-I170 HydrophobicContact CZ-CG1 3.57Å; F166-I170 WeakPolarHBondContact O-CG1 3.19Å; F166-I170 PolarHBondContact O-N 2.94Å; M167-I170 PolarHBondContact O-N 2.75Å; M167-I170 HydrophobicContact SD-CD1 4.22Å; I170-S172 VanDerWaalsContact C-N 3.27Å; I170-S172 PolarHBondContact O-N 3.42Å; I170-I173 PolarHBondContact O-N 2.84Å; I170-I174 HydrophobicContact CG2-CD1 3.61Å; I170-I174 HydrophobicContact CG2-CG1 4.19Å; I170-I174 WeakPolarHBondContact O-CG1 3.48Å; I170-I174 PolarHBondContact O-N 2.73Å; I170-I202 HydrophobicContact CG1-CG2 4.22Å; I170-I202 HydrophobicContact CG2-CG2 4.2Å
171	A	78	Confident	78.4	Confident	58 Å²	58	80.3 Å²	80.3	48%	0.479	39%	0.393	S	S	.	.	H	α-helix	trans	-60	-37.8	-179.3	0	0	0	0	0	112.2	M167 I168 L175	M167-A171 WeakPolarHBondContact O-CB 3.12Å; M167-A171 PolarHBondContact O-N 2.68Å; I168-A171 PolarHBondContact O-N 3.35Å; A171-L175 WeakPolarHBondContact O-CB 3.49Å; A171-L175 PolarHBondContact O-N 3.28Å
172	S	84.4	Confident	78.6	Confident	56 Å²	56	83.2 Å²	83.2	39%	0.392	40%	0.403	S	S	.	.	H	α-helix	trans	-69	-40.3	177.5	68.4	0	0	0	0	112.6	I168 Y169 I170 L175 V176	I168-S172 PolarHBondContact O-N 3.19Å; I168-S172 PolarHBondContact O-OG 3.38Å; Y169-S172 PolarHBondContact O-N 3.21Å; Y169-S172 PolarHBondContact O-OG 2.95Å; I170-S172 VanDerWaalsContact C-N 3.27Å; I170-S172 PolarHBondContact O-N 3.42Å; S172-L175 WeakPolarHBondContact O-CB 3.22Å; S172-L175 PolarHBondContact O-N 2.82Å; S172-V176 WeakPolarHBondContact O-CG2 3.43Å; S172-V176 PolarHBondContact O-N 2.89Å
173	I	81.5	Confident	78.7	Confident	15 Å²	15	78.8 Å²	78.8	8%	0.077	39%	0.391	C	S	.	.	H	α-helix	trans	-67.9	-41.7	175.6	-63.1	177.8	0	0	0	111.2	Y169 I170 L175 V176 I177 L198 A201 I202	Y169-I173 HydrophobicContact CD1-CD1 4.21Å; Y169-I173 HydrophobicContact CD2-CD1 4.34Å; Y169-I173 HydrophobicContact CE1-CD1 3.52Å; Y169-I173 HydrophobicContact CE2-CD1 3.67Å; Y169-I173 HydrophobicContact CE2-CG1 4.36Å; Y169-I173 PolarHBondContact O-N 3.21Å; Y169-I173 VanDerWaalsContact O-N 3.13Å; Y169-I173 VanDerWaalsContact OH-CD1 3.3Å; Y169-I173 WeakPolarHBondContact OH-CD1 3.35Å; I170-I173 PolarHBondContact O-N 2.84Å; I173-L175 PolarHBondContact O-N 3.04Å; I173-V176 WeakPolarHBondContact O-CA 3.41Å; I173-V176 WeakPolarHBondContact O-CB 3.37Å; I173-V176 PolarHBondContact O-N 3.31Å; I173-I177 HydrophobicContact CG2-CD1 4.01Å; I173-I177 HydrophobicContact CG2-CG1 4.3Å; I173-I177 WeakPolarHBondContact O-CG1 3.22Å; I173-I177 PolarHBondContact O-N 3.38Å; I173-L198 HydrophobicContact CG2-CB 4.14Å; I173-L198 HydrophobicContact CG2-CD2 4.19Å; I173-A201 HydrophobicContact CD1-CB 4.2Å; I173-I202 HydrophobicContact CB-CD1 3.88Å; I173-I202 HydrophobicContact CB-CG1 3.82Å; I173-I202 HydrophobicContact CD1-CG1 3.91Å; I173-I202 HydrophobicContact CG1-CG1 4.46Å; I173-I202 HydrophobicContact CG2-CD1 3.55Å; I173-I202 HydrophobicContact CG2-CG1 3.69Å
174	I	79.9	Confident	78.6	Confident	80 Å²	80	79.5 Å²	79.5	41%	0.41	39%	0.392	S	S	.	.	H	α-helix	trans	-57.5	-42.7	175	-69.3	173.3	0	0	0	110.1	I170 V176 I177 L178 I202	I170-I174 HydrophobicContact CG2-CD1 3.61Å; I170-I174 HydrophobicContact CG2-CG1 4.19Å; I170-I174 WeakPolarHBondContact O-CG1 3.48Å; I170-I174 PolarHBondContact O-N 2.73Å; I174-V176 VanDerWaalsContact C-N 3.33Å; I174-V176 PolarHBondContact O-N 3.06Å; I174-I177 PolarHBondContact O-N 3.07Å; I174-L178 HydrophobicContact CG2-CD1 4.17Å; I174-L178 HydrophobicContact CG2-CG 4.41Å; I174-L178 WeakPolarHBondContact O-CG 3.27Å; I174-L178 PolarHBondContact O-N 2.72Å; I174-I202 HydrophobicContact CG1-CD1 4.11Å
175	L	82	Confident	78.4	Confident	104 Å²	104	73.7 Å²	73.7	55%	0.545	38%	0.384	S	S	.	.	H	α-helix	trans	-59.9	-42.2	174.9	-177.6	65.3	0	0	0	112.1	A171 S172 I173 L178 I179	A171-L175 WeakPolarHBondContact O-CB 3.49Å; A171-L175 PolarHBondContact O-N 3.28Å; S172-L175 WeakPolarHBondContact O-CB 3.22Å; S172-L175 PolarHBondContact O-N 2.82Å; I173-L175 PolarHBondContact O-N 3.04Å; L175-L178 PolarHBondContact O-N 3.33Å; L175-I179 HydrophobicContact CG-CD1 4.26Å; L175-I179 WeakPolarHBondContact O-CG1 3.27Å; L175-I179 PolarHBondContact O-N 2.99Å
176	V	84.7	Confident	78.4	Confident	67 Å²	67	70.8 Å²	70.8	41%	0.406	38%	0.381	S	S	.	.	H	α-helix	trans	-62.5	-44.2	175	173.8	0	0	0	0	111.3	S172 I173 I174 L178 I179 L180 L198	S172-V176 WeakPolarHBondContact O-CG2 3.43Å; S172-V176 PolarHBondContact O-N 2.89Å; I173-V176 WeakPolarHBondContact O-CA 3.41Å; I173-V176 WeakPolarHBondContact O-CB 3.37Å; I173-V176 PolarHBondContact O-N 3.31Å; I174-V176 VanDerWaalsContact C-N 3.33Å; I174-V176 PolarHBondContact O-N 3.06Å; V176-L178 VanDerWaalsContact C-N 3.33Å; V176-L178 PolarHBondContact O-N 2.71Å; V176-I179 PolarHBondContact O-N 3.39Å; V176-L180 HydrophobicContact CG1-CD1 4.09Å; V176-L180 HydrophobicContact CG1-CG 4.44Å; V176-L180 WeakPolarHBondContact O-CG 3.17Å; V176-L180 PolarHBondContact O-N 3.37Å; V176-L198 HydrophobicContact CG1-CD1 4.11Å
177	I	78.6	Confident	78	Confident	27 Å²	27	76.5 Å²	76.5	14%	0.138	41%	0.413	C	S	.	.	H	α-helix	trans	-59.6	-45.5	176.2	-67.3	170	0	0	0	110.1	I173 I174 I179 L180 L181 L198 V199 I202	I173-I177 HydrophobicContact CG2-CD1 4.01Å; I173-I177 HydrophobicContact CG2-CG1 4.3Å; I173-I177 WeakPolarHBondContact O-CG1 3.22Å; I173-I177 PolarHBondContact O-N 3.38Å; I174-I177 PolarHBondContact O-N 3.07Å; I177-I179 VanDerWaalsContact C-N 3.33Å; I177-I179 PolarHBondContact O-N 3.21Å; I177-L180 WeakPolarHBondContact O-CB 3.18Å; I177-L180 PolarHBondContact O-N 3.01Å; I177-L180 VanDerWaalsContact O-N 3.11Å; I177-L181 WeakPolarHBondContact O-CG 3.49Å; I177-L181 PolarHBondContact O-N 3.11Å; I177-L198 HydrophobicContact CD1-CB 4.26Å; I177-L198 HydrophobicContact CG1-CB 4.15Å; I177-L198 HydrophobicContact CG1-CD1 4.22Å; I177-V199 HydrophobicContact CD1-CG2 4.26Å; I177-I202 HydrophobicContact CD1-CD1 4.15Å
178	L	79.4	Confident	77.7	Confident	100 Å²	100	75 Å²	75	52%	0.524	41%	0.409	S	S	.	.	H	α-helix	trans	-59.8	-40.8	177.3	-72	172.3	0	0	0	112.4	I174 L175 V176 L180 L181	I174-L178 HydrophobicContact CG2-CD1 4.17Å; I174-L178 HydrophobicContact CG2-CG 4.41Å; I174-L178 WeakPolarHBondContact O-CG 3.27Å; I174-L178 PolarHBondContact O-N 2.72Å; L175-L178 PolarHBondContact O-N 3.33Å; V176-L178 VanDerWaalsContact C-N 3.33Å; V176-L178 PolarHBondContact O-N 2.71Å; L178-L180 VanDerWaalsContact C-N 3.34Å; L178-L181 HydrophobicContact CD2-CD1 3.99Å; L178-L181 WeakPolarHBondContact O-CB 3.38Å; L178-L181 PolarHBondContact O-N 2.84Å
179	I	82	Confident	76.9	Confident	98 Å²	98	75.2 Å²	75.2	50%	0.503	42%	0.415	S	S	.	.	H	α-helix	trans	-64.7	-41	175	-67.2	164.7	0	0	0	110.5	L175 V176 I177 L181 I182 P183	L175-I179 HydrophobicContact CG-CD1 4.26Å; L175-I179 WeakPolarHBondContact O-CG1 3.27Å; L175-I179 PolarHBondContact O-N 2.99Å; V176-I179 PolarHBondContact O-N 3.39Å; I177-I179 VanDerWaalsContact C-N 3.33Å; I177-I179 PolarHBondContact O-N 3.21Å; I179-L181 VanDerWaalsContact C-N 3.26Å; I179-L181 PolarHBondContact O-N 3.09Å; I179-I182 WeakPolarHBondContact O-CB 3.49Å; I179-I182 PolarHBondContact O-N 3.02Å; I179-P183 VanDerWaalsContact O-CD 3.28Å; I179-P183 WeakPolarHBondContact O-CD 3.41Å
180	L	81.4	Confident	76.4	Confident	38 Å²	38	73.7 Å²	73.7	20%	0.199	42%	0.422	C	S	.	.	H	α-helix	trans	-66.1	-24.5	178.5	-74.2	175.3	0	0	0	113.3	V176 I177 L178 I182 P183 W184 V191 A194 L198	V176-L180 HydrophobicContact CG1-CD1 4.09Å; V176-L180 HydrophobicContact CG1-CG 4.44Å; V176-L180 WeakPolarHBondContact O-CG 3.17Å; V176-L180 PolarHBondContact O-N 3.37Å; I177-L180 WeakPolarHBondContact O-CB 3.18Å; I177-L180 PolarHBondContact O-N 3.01Å; I177-L180 VanDerWaalsContact O-N 3.11Å; L178-L180 VanDerWaalsContact C-N 3.34Å; L180-I182 PolarHBondContact O-N 2.95Å; L180-I182 VanDerWaalsContact O-N 3.14Å; L180-P183 HydrophobicContact CD2-CG 4.5Å; L180-P183 WeakPolarHBondContact O-CD 3.37Å; L180-P183 WeakPolarHBondContact O-CG 3.49Å; L180-W184 WeakPolarHBondContact O-CB 3.47Å; L180-W184 PolarHBondContact O-N 3.42Å; L180-V191 HydrophobicContact CB-CG1 3.87Å; L180-V191 HydrophobicContact CD2-CG1 4.36Å; L180-V191 WeakPolarHBondContact O-CG1 3.39Å; L180-A194 HydrophobicContact CD1-CB 4.19Å; L180-L198 HydrophobicContact CD1-CD1 3.44Å; L180-L198 VanDerWaalsContact CD1-CD1 3.44Å
181	L	74.1	Confident	76	Confident	69 Å²	69	72.7 Å²	72.7	36%	0.361	42%	0.417	S	S	.	.	H	α-helix	trans	-58.7	-26.1	173.1	-65.4	175	0	0	0	112.7	I177 L178 I179 W184 S185	I177-L181 WeakPolarHBondContact O-CG 3.49Å; I177-L181 PolarHBondContact O-N 3.11Å; L178-L181 HydrophobicContact CD2-CD1 3.99Å; L178-L181 WeakPolarHBondContact O-CB 3.38Å; L178-L181 PolarHBondContact O-N 2.84Å; I179-L181 VanDerWaalsContact C-N 3.26Å; I179-L181 PolarHBondContact O-N 3.09Å; L181-W184 HydrophobicContact CD2-CE3 3.69Å; L181-W184 HydrophobicContact CD2-CZ3 4.08Å; L181-W184 PolarHBondContact O-N 3.46Å; L181-S185 PolarHBondContact O-N 3.44Å
182	I	76.3	Confident	75.4	Confident	110 Å²	110	70.9 Å²	70.9	56%	0.564	40%	0.4	S	S	*	.	H	α-helix	trans	-64.9	-60.5	177.2	-57.6	169.6	0	0	0	111.2	I179 L180 W184 S185	I179-I182 WeakPolarHBondContact O-CB 3.49Å; I179-I182 PolarHBondContact O-N 3.02Å; L180-I182 PolarHBondContact O-N 2.95Å; L180-I182 VanDerWaalsContact O-N 3.14Å; I182-W184 PolarHBondContact O-N 3.32Å; I182-S185 WeakPolarHBondContact O-CB 3.42Å; I182-S185 PolarHBondContact O-N 2.92Å; I182-S185 VanDerWaalsContact O-N 3.1Å; I182-S185 PolarHBondContact O-OG 2.93Å
183	P	75.9	Confident	74.6	Confident	41 Å²	41	73.7 Å²	73.7	27%	0.266	40%	0.402	S	S	.	.	H	α-helix	trans	-65	-25.2	175.4	22.3	-30.6	0	0	0	113.2	I179 L180 S185 I186 V188 V191	I179-P183 VanDerWaalsContact O-CD 3.28Å; I179-P183 WeakPolarHBondContact O-CD 3.41Å; L180-P183 HydrophobicContact CD2-CG 4.5Å; L180-P183 WeakPolarHBondContact O-CD 3.37Å; L180-P183 WeakPolarHBondContact O-CG 3.49Å; P183-S185 VanDerWaalsContact C-N 3.32Å; P183-S185 PolarHBondContact O-N 3.46Å; P183-I186 PolarHBondContact O-N 3.24Å; P183-I186 VanDerWaalsContact O-N 3.15Å; P183-V188 HydrophobicContact CB-CB 4.41Å; P183-V188 HydrophobicContact CB-CG2 4.19Å; P183-V188 WeakPolarHBondContact O-CB 3.38Å; P183-V188 WeakPolarHBondContact O-CG2 3.4Å; P183-V188 PolarHBondContact O-N 2.94Å; P183-V191 HydrophobicContact CB-CG2 3.84Å; P183-V191 HydrophobicContact CG-CG2 3.85Å
184	W	70.2	Confident	74.3	Confident	62 Å²	62	74.6 Å²	74.6	24%	0.235	41%	0.412	C	S	.	.	H	α-helix	trans	-62.4	-38.7	170.7	-172.5	49.3	0	0	0	112.4	Y77 I81 L180 L181 I182 I186 N187 V191	Y77-W184 AromaticContact CE1-CH2 3.94Å; Y77-W184 HydrophobicContact CE1-CH2 3.94Å; Y77-W184 HydrophobicContact CE1-CZ2 4.14Å; Y77-W184 WeakPolarHBondContact OH-CH2 3.36Å; Y77-W184 VanDerWaalsContact OH-CZ2 3.26Å; Y77-W184 WeakPolarHBondContact OH-CZ2 3.42Å; I81-W184 HydrophobicContact CD1-CH2 3.77Å; I81-W184 HydrophobicContact CD1-CZ3 4.07Å; L180-W184 WeakPolarHBondContact O-CB 3.47Å; L180-W184 PolarHBondContact O-N 3.42Å; L181-W184 HydrophobicContact CD2-CE3 3.69Å; L181-W184 HydrophobicContact CD2-CZ3 4.08Å; L181-W184 PolarHBondContact O-N 3.46Å; I182-W184 PolarHBondContact O-N 3.32Å; W184-I186 PolarHBondContact O-N 3.36Å; W184-I186 VanDerWaalsContact O-N 3.1Å; W184-N187 PolarHBondContact O-N 3.02Å; W184-V191 HydrophobicContact CB-CB 4.3Å; W184-V191 HydrophobicContact CB-CG1 3.8Å; W184-V191 HydrophobicContact CG-CG1 4.46Å
185	S	70.1	Confident	74.1	Confident	91 Å²	91	71.9 Å²	71.9	64%	0.636	40%	0.398	S	S	*	.	H	α-helix	trans	-62.8	-16.2	175.1	78.3	0	0	0	0	114.1	L181 I182 P183	L181-S185 PolarHBondContact O-N 3.44Å; I182-S185 WeakPolarHBondContact O-CB 3.42Å; I182-S185 PolarHBondContact O-N 2.92Å; I182-S185 VanDerWaalsContact O-N 3.1Å; I182-S185 PolarHBondContact O-OG 2.93Å; P183-S185 VanDerWaalsContact C-N 3.32Å; P183-S185 PolarHBondContact O-N 3.46Å
186	I	76.4	Confident	73.6	Confident	125 Å²	125	66.9 Å²	66.9	64%	0.641	37%	0.372	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101.9	17.6	177.2	-45.7	168.8	0	0	0	110.2	P183 W184 V188	P183-I186 PolarHBondContact O-N 3.24Å; P183-I186 VanDerWaalsContact O-N 3.15Å; W184-I186 PolarHBondContact O-N 3.36Å; W184-I186 VanDerWaalsContact O-N 3.1Å; I186-V188 VanDerWaalsContact C-N 3.28Å; I186-V188 PolarHBondContact O-N 2.94Å
187	N	68.7	Low	73.4	Confident	141 Å²	141	66.3 Å²	66.3	75%	0.754	37%	0.37	S	S	*	.	T	Hydrogen-bonded Turn	trans	57.3	32.9	178.4	-67.5	-28.6	0	0	0	114.7	W184 T189	W184-N187 PolarHBondContact O-N 3.02Å; N187-T189 PolarHBondContact O-N 3.36Å
188	V	69.2	Low	73.6	Confident	63 Å²	63	67 Å²	67	38%	0.382	37%	0.374	S	S	.	.			trans	-72.7	102.5	171.4	-178.9	0	0	0	0	108.9	P183 I186 A190 V191	P183-V188 HydrophobicContact CB-CB 4.41Å; P183-V188 HydrophobicContact CB-CG2 4.19Å; P183-V188 WeakPolarHBondContact O-CB 3.38Å; P183-V188 WeakPolarHBondContact O-CG2 3.4Å; P183-V188 PolarHBondContact O-N 2.94Å; I186-V188 VanDerWaalsContact C-N 3.28Å; I186-V188 PolarHBondContact O-N 2.94Å; V188-A190 HydrophobicContact CG1-CB 4.14Å; V188-A190 PolarHBondContact O-N 3.23Å; V188-V191 HydrophobicContact CB-CG2 3.87Å; V188-V191 HydrophobicContact CG1-CG2 3.92Å; V188-V191 WeakPolarHBondContact O-CB 3.44Å; V188-V191 PolarHBondContact O-N 3.35Å
189	T	65.2	Low	73.6	Confident	109 Å²	109	62.7 Å²	62.7	67%	0.669	35%	0.351	S	S	*	.	H	α-helix	trans	-56.1	-35.9	-178.2	53.9	0	0	0	0	112.5	N187 V191 T192 W193	N187-T189 PolarHBondContact O-N 3.36Å; T189-V191 PolarHBondContact O-N 2.99Å; T189-T192 PolarHBondContact O-N 3.12Å; T189-T192 VanDerWaalsContact O-N 3.1Å; T189-T192 PolarHBondContact O-OG1 3.46Å; T189-W193 VanDerWaalsContact O-CD1 3.32Å
190	A	69.3	Low	73.5	Confident	63 Å²	63	59.3 Å²	59.3	52%	0.521	33%	0.334	S	S	.	.	H	α-helix	trans	-57.8	-21.8	177.1	0	0	0	0	0	114	V188 W193 A194	V188-A190 HydrophobicContact CG1-CB 4.14Å; V188-A190 PolarHBondContact O-N 3.23Å; A190-W193 WeakPolarHBondContact O-CB 3.41Å; A190-A194 PolarHBondContact O-N 2.86Å
191	V	69.4	Low	73.5	Confident	9 Å²	9	58.9 Å²	58.9	6%	0.055	34%	0.336	C	S	.	.	H	α-helix	trans	-73.2	-36.8	178.6	179.6	0	0	0	0	111.7	L180 P183 W184 V188 T189 W193 A194 I195	L180-V191 HydrophobicContact CB-CG1 3.87Å; L180-V191 HydrophobicContact CD2-CG1 4.36Å; L180-V191 WeakPolarHBondContact O-CG1 3.39Å; P183-V191 HydrophobicContact CB-CG2 3.84Å; P183-V191 HydrophobicContact CG-CG2 3.85Å; W184-V191 HydrophobicContact CB-CB 4.3Å; W184-V191 HydrophobicContact CB-CG1 3.8Å; W184-V191 HydrophobicContact CG-CG1 4.46Å; V188-V191 HydrophobicContact CB-CG2 3.87Å; V188-V191 HydrophobicContact CG1-CG2 3.92Å; V188-V191 WeakPolarHBondContact O-CB 3.44Å; V188-V191 PolarHBondContact O-N 3.35Å; T189-V191 PolarHBondContact O-N 2.99Å; V191-W193 VanDerWaalsContact C-N 3.26Å; V191-W193 PolarHBondContact O-N 2.9Å; V191-A194 PolarHBondContact O-N 3.37Å; V191-I195 HydrophobicContact CG1-CD1 3.96Å; V191-I195 HydrophobicContact CG1-CG1 4.29Å; V191-I195 WeakPolarHBondContact O-CG1 3.39Å; V191-I195 PolarHBondContact O-N 3.5Å; V191-I195 VanDerWaalsContact O-N 3.09Å
192	T	65	Low	73.8	Confident	21 Å²	21	56.2 Å²	56.2	13%	0.129	32%	0.322	C	S	.	.	H	α-helix	trans	-64.5	-35.3	176.9	58.4	0	0	0	0	111.1	T189 A194 I195	T189-T192 PolarHBondContact O-N 3.12Å; T189-T192 VanDerWaalsContact O-N 3.1Å; T189-T192 PolarHBondContact O-OG1 3.46Å; T192-A194 VanDerWaalsContact C-N 3.26Å; T192-A194 PolarHBondContact O-N 2.94Å; T192-I195 PolarHBondContact O-N 2.86Å
193	W	67.5	Low	74.1	Confident	114 Å²	114	51 Å²	51	43%	0.432	30%	0.295	S	S	.	.	H	α-helix	trans	-60.8	-32.6	171.9	-72.4	84.9	0	0	0	113.4	T189 A190 V191 P197 A251	T189-W193 VanDerWaalsContact O-CD1 3.32Å; A190-W193 WeakPolarHBondContact O-CB 3.41Å; V191-W193 VanDerWaalsContact C-N 3.26Å; V191-W193 PolarHBondContact O-N 2.9Å; W193-P197 WeakPolarHBondContact O-CD 3.37Å; W193-P197 VanDerWaalsContact O-CG 3.31Å; W193-P197 WeakPolarHBondContact O-CG 3.29Å; W193-A251 HydrophobicContact CB-CB 4.26Å; W193-A251 HydrophobicContact CD2-CB 3.66Å; W193-A251 HydrophobicContact CE3-CB 4.3Å; W193-A251 HydrophobicContact CG-CB 3.61Å; W193-A251 WeakPolarHBondContact CZ2-O 3.46Å; W193-A251 PolarHBondContact NE1-O 3.3Å
194	A	75.1	Confident	74.3	Confident	35 Å²	35	52.4 Å²	52.4	29%	0.289	30%	0.3	S	S	.	.	H	α-helix	trans	-82.8	-34.8	-178.1	0	0	0	0	0	112.4	L180 A190 V191 T192 P197 L198	L180-A194 HydrophobicContact CD1-CB 4.19Å; A190-A194 PolarHBondContact O-N 2.86Å; V191-A194 PolarHBondContact O-N 3.37Å; T192-A194 VanDerWaalsContact C-N 3.26Å; T192-A194 PolarHBondContact O-N 2.94Å; A194-P197 WeakPolarHBondContact O-CD 3.41Å; A194-L198 HydrophobicContact CB-CD1 4.5Å; A194-L198 WeakPolarHBondContact O-CB 3.42Å; A194-L198 WeakPolarHBondContact O-CD1 3.29Å; A194-L198 WeakPolarHBondContact O-CG 3.17Å; A194-L198 PolarHBondContact O-N 3.39Å; A194-L198 VanDerWaalsContact O-N 3.14Å
195	I	74.8	Confident	74.9	Confident	22 Å²	22	51 Å²	51	11%	0.113	30%	0.299	C	S	.	.	H	α-helix	trans	-63.5	-46.2	-175.6	-67.7	166.4	0	0	0	111.5	V191 T192 L198 V199 T247	V191-I195 HydrophobicContact CG1-CD1 3.96Å; V191-I195 HydrophobicContact CG1-CG1 4.29Å; V191-I195 WeakPolarHBondContact O-CG1 3.39Å; V191-I195 PolarHBondContact O-N 3.5Å; V191-I195 VanDerWaalsContact O-N 3.09Å; T192-I195 PolarHBondContact O-N 2.86Å; I195-L198 PolarHBondContact O-N 3.25Å; I195-V199 HydrophobicContact CG2-CG2 4.18Å; I195-V199 WeakPolarHBondContact O-CG2 3.5Å; I195-V199 PolarHBondContact O-N 3.3Å; I195-T247 HydrophobicContact CB-CG2 4.13Å; I195-T247 HydrophobicContact CG2-CG2 4.06Å
196	G	73.5	Confident	75.4	Confident	0 Å²	0	47.3 Å²	47.3	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-56.4	-54.5	-178.9	0	0	0	0	0	113.8	L198 V199 L200 G244	G196-L198 VanDerWaalsContact C-N 3.33Å; G196-L198 PolarHBondContact O-N 3.49Å; G196-V199 WeakPolarHBondContact O-CB 3.28Å; G196-V199 PolarHBondContact O-N 3.11Å; G196-L200 WeakPolarHBondContact O-CG 3.26Å; G196-L200 PolarHBondContact O-N 2.91Å; G196-G244 WeakPolarHBondContact CA-O 3.33Å
197	P	79.9	Confident	75.7	Confident	55 Å²	55	42 Å²	42	36%	0.357	25%	0.247	S	C	.	.	H	α-helix	trans	-62.3	-35.1	175.6	-25.7	36.5	0	0	0	113.6	W193 A194 L200 A201 Y248	W193-P197 WeakPolarHBondContact O-CD 3.37Å; W193-P197 VanDerWaalsContact O-CG 3.31Å; W193-P197 WeakPolarHBondContact O-CG 3.29Å; A194-P197 WeakPolarHBondContact O-CD 3.41Å; P197-L200 PolarHBondContact O-N 2.95Å; P197-A201 WeakPolarHBondContact O-CB 3.29Å; P197-A201 PolarHBondContact O-N 3.04Å; P197-Y248 HydrophobicContact CG-CD2 3.78Å; P197-Y248 HydrophobicContact CG-CE2 3.97Å
198	L	82.7	Confident	76.3	Confident	42 Å²	42	36.6 Å²	36.6	22%	0.22	22%	0.219	C	C	.	.	H	α-helix	trans	-65.7	-40.2	175.1	-73.3	170.9	0	0	0	111.9	I173 V176 I177 L180 A194 I195 G196 A201 I202	I173-L198 HydrophobicContact CG2-CB 4.14Å; I173-L198 HydrophobicContact CG2-CD2 4.19Å; V176-L198 HydrophobicContact CG1-CD1 4.11Å; I177-L198 HydrophobicContact CD1-CB 4.26Å; I177-L198 HydrophobicContact CG1-CB 4.15Å; I177-L198 HydrophobicContact CG1-CD1 4.22Å; L180-L198 HydrophobicContact CD1-CD1 3.44Å; L180-L198 VanDerWaalsContact CD1-CD1 3.44Å; A194-L198 HydrophobicContact CB-CD1 4.5Å; A194-L198 WeakPolarHBondContact O-CB 3.42Å; A194-L198 WeakPolarHBondContact O-CD1 3.29Å; A194-L198 WeakPolarHBondContact O-CG 3.17Å; A194-L198 PolarHBondContact O-N 3.39Å; A194-L198 VanDerWaalsContact O-N 3.14Å; I195-L198 PolarHBondContact O-N 3.25Å; G196-L198 VanDerWaalsContact C-N 3.33Å; G196-L198 PolarHBondContact O-N 3.49Å; L198-A201 WeakPolarHBondContact O-CB 3.35Å; L198-A201 PolarHBondContact O-N 2.86Å; L198-I202 PolarHBondContact O-N 3.17Å
199	V	78.4	Confident	76.8	Confident	9 Å²	9	34.2 Å²	34.2	6%	0.055	20%	0.203	C	C	.	.	H	α-helix	trans	-60.6	-47.7	172.6	166.1	0	0	0	0	110.2	I177 I195 G196 A201 I202 I203 F240	I177-V199 HydrophobicContact CD1-CG2 4.26Å; I195-V199 HydrophobicContact CG2-CG2 4.18Å; I195-V199 WeakPolarHBondContact O-CG2 3.5Å; I195-V199 PolarHBondContact O-N 3.3Å; G196-V199 WeakPolarHBondContact O-CB 3.28Å; G196-V199 PolarHBondContact O-N 3.11Å; V199-A201 VanDerWaalsContact C-N 3.3Å; V199-A201 PolarHBondContact O-N 2.93Å; V199-I202 WeakPolarHBondContact O-CB 3.34Å; V199-I202 PolarHBondContact O-N 3.35Å; V199-I202 VanDerWaalsContact O-N 3.15Å; V199-I203 HydrophobicContact CG1-CD1 3.57Å; V199-I203 VanDerWaalsContact O-CD1 3.25Å; V199-I203 WeakPolarHBondContact O-CD1 3.34Å; V199-I203 VanDerWaalsContact O-CG1 3.28Å; V199-I203 WeakPolarHBondContact O-CG1 2.84Å; V199-I203 PolarHBondContact O-N 3.43Å; V199-F240 HydrophobicContact CB-CE1 4.32Å; V199-F240 HydrophobicContact CG1-CD1 3.59Å; V199-F240 HydrophobicContact CG1-CE1 3.69Å; V199-F240 HydrophobicContact CG1-CG 4.2Å; V199-F240 HydrophobicContact CG1-CZ 4.41Å; V199-F240 WeakPolarHBondContact CG1-O 3.37Å; V199-F240 HydrophobicContact CG2-CE1 4.17Å; V199-F240 HydrophobicContact CG2-CZ 4.38Å
200	L	80.4	Confident	77.4	Confident	27 Å²	27	29.4 Å²	29.4	14%	0.141	17%	0.173	C	C	.	.	H	α-helix	trans	-62.7	-34.5	176.1	-67.5	175.3	0	0	0	112.8	L144 G196 P197 I202 I203 I204 F245	L144-L200 HydrophobicContact CD2-CD2 4.09Å; G196-L200 WeakPolarHBondContact O-CG 3.26Å; G196-L200 PolarHBondContact O-N 2.91Å; P197-L200 PolarHBondContact O-N 2.95Å; L200-I202 VanDerWaalsContact C-N 3.27Å; L200-I202 PolarHBondContact O-N 3.4Å; L200-I203 HydrophobicContact CD2-CD1 4.38Å; L200-I203 PolarHBondContact O-N 3.3Å; L200-I203 VanDerWaalsContact O-N 3.12Å; L200-I204 WeakPolarHBondContact O-CG1 3.43Å; L200-I204 PolarHBondContact O-N 3.18Å; L200-F245 HydrophobicContact CD1-CD1 4.4Å; L200-F245 HydrophobicContact CD1-CE1 4.1Å; L200-F245 HydrophobicContact CD1-CZ 4.3Å; L200-F245 HydrophobicContact CD2-CD2 4.25Å; L200-F245 HydrophobicContact CD2-CE2 3.96Å; L200-F245 HydrophobicContact CD2-CZ 4.2Å
201	A	80.9	Confident	77.8	Confident	29 Å²	29	26.4 Å²	26.4	24%	0.24	15%	0.149	C	C	.	.	H	α-helix	trans	-64.6	-29.2	176.1	0	0	0	0	0	112.9	Y169 I173 P197 L198 V199 P205	Y169-A201 PolarHBondContact OH-O 3.39Å; I173-A201 HydrophobicContact CD1-CB 4.2Å; P197-A201 WeakPolarHBondContact O-CB 3.29Å; P197-A201 PolarHBondContact O-N 3.04Å; L198-A201 WeakPolarHBondContact O-CB 3.35Å; L198-A201 PolarHBondContact O-N 2.86Å; V199-A201 VanDerWaalsContact C-N 3.3Å; V199-A201 PolarHBondContact O-N 2.93Å; A201-P205 WeakPolarHBondContact O-CD 2.89Å; A201-P205 VanDerWaalsContact O-CG 3.22Å; A201-P205 WeakPolarHBondContact O-CG 3.45Å
202	I	81.5	Confident	78.1	Confident	12 Å²	12	26.7 Å²	26.7	6%	0.062	15%	0.149	C	C	.	.	H	α-helix	trans	-72.5	-43.9	170	-69.1	168.2	0	0	0	110.7	I170 I173 I174 I177 L198 V199 L200 P205 A206	I170-I202 HydrophobicContact CG1-CG2 4.22Å; I170-I202 HydrophobicContact CG2-CG2 4.2Å; I173-I202 HydrophobicContact CB-CD1 3.88Å; I173-I202 HydrophobicContact CB-CG1 3.82Å; I173-I202 HydrophobicContact CD1-CG1 3.91Å; I173-I202 HydrophobicContact CG1-CG1 4.46Å; I173-I202 HydrophobicContact CG2-CD1 3.55Å; I173-I202 HydrophobicContact CG2-CG1 3.69Å; I174-I202 HydrophobicContact CG1-CD1 4.11Å; I177-I202 HydrophobicContact CD1-CD1 4.15Å; L198-I202 PolarHBondContact O-N 3.17Å; V199-I202 WeakPolarHBondContact O-CB 3.34Å; V199-I202 PolarHBondContact O-N 3.35Å; V199-I202 VanDerWaalsContact O-N 3.15Å; L200-I202 VanDerWaalsContact C-N 3.27Å; L200-I202 PolarHBondContact O-N 3.4Å; I202-P205 WeakPolarHBondContact O-CD 3.09Å; I202-P205 WeakPolarHBondContact O-CG 3.49Å; I202-A206 WeakPolarHBondContact O-CB 3.4Å; I202-A206 PolarHBondContact O-N 3.38Å
203	I	82.6	Confident	78.6	Confident	2 Å²	2	25.9 Å²	25.9	1%	0.01	14%	0.144	C	C	.	.	H	α-helix	trans	-75.4	-38.4	-167.5	-64.9	156	0	0	0	113.1	V199 L200 A206 S207 F240	V199-I203 HydrophobicContact CG1-CD1 3.57Å; V199-I203 VanDerWaalsContact O-CD1 3.25Å; V199-I203 WeakPolarHBondContact O-CD1 3.34Å; V199-I203 VanDerWaalsContact O-CG1 3.28Å; V199-I203 WeakPolarHBondContact O-CG1 2.84Å; V199-I203 PolarHBondContact O-N 3.43Å; L200-I203 HydrophobicContact CD2-CD1 4.38Å; L200-I203 PolarHBondContact O-N 3.3Å; L200-I203 VanDerWaalsContact O-N 3.12Å; I203-A206 PolarHBondContact O-N 3.5Å; I203-S207 WeakPolarHBondContact CG2-OG 3.11Å; I203-S207 WeakPolarHBondContact O-CB 3.36Å; I203-S207 PolarHBondContact O-N 3.39Å; I203-S207 PolarHBondContact O-OG 3.25Å; I203-F240 HydrophobicContact CD1-CB 3.83Å; I203-F240 HydrophobicContact CD1-CD1 3.67Å; I203-F240 HydrophobicContact CD1-CG 4.16Å; I203-F240 WeakPolarHBondContact CD1-O 3.48Å; I203-F240 HydrophobicContact CG1-CB 4.1Å; I203-F240 HydrophobicContact CG1-CD1 3.69Å; I203-F240 HydrophobicContact CG1-CG 4.37Å
204	I	80.4	Confident	79	Confident	70 Å²	70	20.4 Å²	20.4	36%	0.359	12%	0.123	S	C	.	.	H	α-helix	trans	-53.9	-59.3	-179.7	-71.7	165.5	0	0	0	110.7	L148 L200 A206 S207 L208	L148-I204 HydrophobicContact CD1-CG1 4.21Å; L148-I204 HydrophobicContact CD2-CB 4.48Å; L148-I204 HydrophobicContact CD2-CG1 4.48Å; L148-I204 HydrophobicContact CD2-CG2 3.93Å; L200-I204 WeakPolarHBondContact O-CG1 3.43Å; L200-I204 PolarHBondContact O-N 3.18Å; I204-A206 PolarHBondContact O-N 3.12Å; I204-S207 PolarHBondContact O-N 2.95Å; I204-L208 HydrophobicContact CG2-CD1 4.36Å; I204-L208 WeakPolarHBondContact O-CG 3.18Å; I204-L208 PolarHBondContact O-N 3.35Å
205	P	81.2	Confident	78.9	Confident	33 Å²	33	21.6 Å²	21.6	21%	0.214	12%	0.121	C	C	.	.	H	α-helix	trans	-65.8	-34.7	177.4	25	-34.3	0	0	0	113.1	F166 Y169 A201 I202 S207 L208 I209	F166-P205 HydrophobicContact CD2-CB 4.05Å; F166-P205 HydrophobicContact CD2-CG 4.41Å; F166-P205 HydrophobicContact CE2-CB 3.47Å; F166-P205 VanDerWaalsContact CE2-CB 3.47Å; F166-P205 HydrophobicContact CE2-CG 3.51Å; F166-P205 HydrophobicContact CZ-CB 4.18Å; F166-P205 HydrophobicContact CZ-CG 4.2Å; Y169-P205 HydrophobicContact CE1-CG 3.88Å; A201-P205 WeakPolarHBondContact O-CD 2.89Å; A201-P205 VanDerWaalsContact O-CG 3.22Å; A201-P205 WeakPolarHBondContact O-CG 3.45Å; I202-P205 WeakPolarHBondContact O-CD 3.09Å; I202-P205 WeakPolarHBondContact O-CG 3.49Å; P205-S207 PolarHBondContact O-N 2.93Å; P205-L208 PolarHBondContact O-N 2.96Å; P205-I209 WeakPolarHBondContact O-CG1 3.44Å; P205-I209 PolarHBondContact O-N 3.45Å; P205-I209 VanDerWaalsContact O-N 3.1Å
206	A	81.7	Confident	78.4	Confident	12 Å²	12	21.9 Å²	21.9	10%	0.099	13%	0.129	C	C	.	.	H	α-helix	trans	-60.6	-47.2	177.2	0	0	0	0	0	112	F166 I202 I203 I204 L208 I209 E210 L237	F166-A206 HydrophobicContact CE1-CB 4.01Å; F166-A206 VanDerWaalsContact CZ-CA 3.41Å; F166-A206 HydrophobicContact CZ-CB 3.63Å; F166-A206 VanDerWaalsContact CZ-N 3.33Å; I202-A206 WeakPolarHBondContact O-CB 3.4Å; I202-A206 PolarHBondContact O-N 3.38Å; I203-A206 PolarHBondContact O-N 3.5Å; I204-A206 PolarHBondContact O-N 3.12Å; A206-L208 VanDerWaalsContact C-N 3.33Å; A206-L208 PolarHBondContact O-N 2.92Å; A206-I209 PolarHBondContact O-N 3.32Å; A206-E210 WeakPolarHBondContact O-CB 3.29Å; A206-E210 PolarHBondContact O-N 3.13Å; A206-L237 HydrophobicContact CB-CD1 4.4Å; A206-L237 HydrophobicContact CB-CD2 3.45Å; A206-L237 VanDerWaalsContact CB-CD2 3.45Å
207	S	82.1	Confident	77.8	Confident	14 Å²	14	22.3 Å²	22.3	10%	0.098	13%	0.134	C	C	.	.	H	α-helix	trans	-64.7	-36.3	179.8	-56.7	0	0	0	0	112.3	I203 I204 P205 A211	I203-S207 WeakPolarHBondContact CG2-OG 3.11Å; I203-S207 WeakPolarHBondContact O-CB 3.36Å; I203-S207 PolarHBondContact O-N 3.39Å; I203-S207 PolarHBondContact O-OG 3.25Å; I204-S207 PolarHBondContact O-N 2.95Å; P205-S207 PolarHBondContact O-N 2.93Å; S207-A211 VanDerWaalsContact O-CB 3.28Å; S207-A211 WeakPolarHBondContact O-CB 3.29Å; S207-A211 PolarHBondContact O-N 3.5Å
208	L	82.1	Confident	77	Confident	28 Å²	28	26.2 Å²	26.2	15%	0.147	14%	0.141	C	C	.	.	H	α-helix	trans	-66.4	-45.7	176.9	-70.2	170.5	0	0	0	111.9	L148 V151 I155 L159 I204 P205 A206 A211 Q212	L148-L208 HydrophobicContact CD2-CD2 4.22Å; L148-L208 HydrophobicContact CD2-CG 4.23Å; L148-L208 WeakPolarHBondContact O-CD2 3.32Å; V151-L208 HydrophobicContact CB-CD2 4.05Å; V151-L208 HydrophobicContact CG1-CD2 3.8Å; I155-L208 HydrophobicContact CD1-CD2 4.19Å; L159-L208 HydrophobicContact CD1-CB 3.96Å; I204-L208 HydrophobicContact CG2-CD1 4.36Å; I204-L208 WeakPolarHBondContact O-CG 3.18Å; I204-L208 PolarHBondContact O-N 3.35Å; P205-L208 PolarHBondContact O-N 2.96Å; A206-L208 VanDerWaalsContact C-N 3.33Å; A206-L208 PolarHBondContact O-N 2.92Å; L208-A211 PolarHBondContact O-N 3.44Å; L208-Q212 PolarHBondContact O-N 3.48Å
209	I	78.8	Confident	75.9	Confident	12 Å²	12	27.7 Å²	27.7	6%	0.062	15%	0.147	C	C	.	.	H	α-helix	trans	-63.9	-46.3	176.7	-69.8	167.7	0	0	0	109.8	L159 F163 F166 P205 A206 A211 Q212 I213	L159-I209 HydrophobicContact CB-CG1 3.95Å; F163-I209 HydrophobicContact CD2-CG2 4.11Å; F166-I209 HydrophobicContact CB-CD1 3.85Å; F166-I209 HydrophobicContact CD1-CD1 3.42Å; F166-I209 VanDerWaalsContact CD1-CD1 3.42Å; F166-I209 HydrophobicContact CD2-CD1 3.91Å; F166-I209 HydrophobicContact CE1-CD1 3.92Å; F166-I209 HydrophobicContact CE2-CD1 4.43Å; F166-I209 HydrophobicContact CG-CD1 3.41Å; F166-I209 VanDerWaalsContact CG-CD1 3.41Å; F166-I209 HydrophobicContact CZ-CD1 4.42Å; P205-I209 WeakPolarHBondContact O-CG1 3.44Å; P205-I209 PolarHBondContact O-N 3.45Å; P205-I209 VanDerWaalsContact O-N 3.1Å; A206-I209 PolarHBondContact O-N 3.32Å; I209-A211 VanDerWaalsContact C-N 3.32Å; I209-A211 PolarHBondContact O-N 3.21Å; I209-Q212 WeakPolarHBondContact O-CB 3.42Å; I209-Q212 PolarHBondContact O-N 2.88Å; I209-Q212 VanDerWaalsContact O-N 3.09Å; I209-I213 HydrophobicContact CG2-CD1 3.81Å; I209-I213 HydrophobicContact CG2-CG1 4.32Å; I209-I213 WeakPolarHBondContact O-CG1 3.4Å; I209-I213 PolarHBondContact O-N 2.97Å
210	E	78.8	Confident	75	Confident	9 Å²	9	28.4 Å²	28.4	4%	0.042	15%	0.15	C	C	.	.	H	α-helix	trans	-62.4	-38.5	-179.3	177.3	61.2	-169.2	0	0	112.2	A206 Q212 I213 L214 Y222 V233 H234 L237	A206-E210 WeakPolarHBondContact O-CB 3.29Å; A206-E210 PolarHBondContact O-N 3.13Å; E210-Q212 VanDerWaalsContact C-N 3.3Å; E210-Q212 PolarHBondContact O-N 2.8Å; E210-I213 PolarHBondContact O-N 3Å; E210-L214 PolarHBondContact O-N 3.12Å; E210-Y222 WeakPolarHBondContact OE1-CE2 3.3Å; E210-Y222 VanDerWaalsContact OE1-CZ 3.28Å; E210-Y222 PolarHBondContact OE1-OH 3Å; E210-Y222 PolarHBondContact OE2-OH 3.15Å; E210-V233 HydrophobicContact CG-CG1 4.01Å; E210-H234 VanDerWaalsContact CD-CE1 3.48Å; E210-H234 WeakPolarHBondContact CG-CE1 3.41Å; E210-H234 IonicContact OE1-CE1 3.88Å; E210-H234 PolarHBondContact OE1-CE1 2.94Å; E210-H234 IonicContact OE1-ND1 4Å; E210-H234 PolarHBondContact OE1-ND1 3.01Å; E210-L237 HydrophobicContact CB-CD1 3.95Å; E210-L237 HydrophobicContact CG-CD1 3.97Å
211	A	77.4	Confident	74.4	Confident	0 Å²	0	30.1 Å²	30.1	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-59.4	-40.9	172.8	0	0	0	0	0	112.3	F149 S207 L208 I209 Y215	F149-A211 HydrophobicContact CD2-CB 3.46Å; F149-A211 VanDerWaalsContact CD2-CB 3.46Å; F149-A211 HydrophobicContact CE2-CB 3.89Å; F149-A211 HydrophobicContact CG-CB 4.21Å; S207-A211 VanDerWaalsContact O-CB 3.28Å; S207-A211 WeakPolarHBondContact O-CB 3.29Å; S207-A211 PolarHBondContact O-N 3.5Å; L208-A211 PolarHBondContact O-N 3.44Å; I209-A211 VanDerWaalsContact C-N 3.32Å; I209-A211 PolarHBondContact O-N 3.21Å; A211-Y215 WeakPolarHBondContact O-CB 3.23Å; A211-Y215 PolarHBondContact O-N 3.18Å
212	Q	75.3	Confident	73.7	Confident	14 Å²	14	29.4 Å²	29.4	7%	0.065	15%	0.146	C	C	.	.	H	α-helix	trans	-67.4	-42.2	174.4	-70	-168.7	-19.3	0	0	112.1	G152 I155 R157 V160 L208 I209 E210 L214 Y215 G216 G217	G152-Q212 WeakPolarHBondContact O-CG 3.27Å; G152-Q212 PolarHBondContact O-NE2 3.48Å; I155-Q212 PolarHBondContact O-NE2 3.39Å; R157-Q212 PolarHBondContact O-NE2 3.31Å; V160-Q212 HydrophobicContact CG2-CB 4.01Å; L208-Q212 PolarHBondContact O-N 3.48Å; I209-Q212 WeakPolarHBondContact O-CB 3.42Å; I209-Q212 PolarHBondContact O-N 2.88Å; I209-Q212 VanDerWaalsContact O-N 3.09Å; E210-Q212 VanDerWaalsContact C-N 3.3Å; E210-Q212 PolarHBondContact O-N 2.8Å; Q212-L214 VanDerWaalsContact C-N 3.34Å; Q212-L214 PolarHBondContact O-N 2.98Å; Q212-Y215 PolarHBondContact O-N 2.95Å; Q212-G216 CarbonylContact O-C 3.53Å; Q212-G216 PolarHBondContact O-N 3.42Å; Q212-G217 PolarHBondContact O-N 3.14Å
213	I	74.8	Confident	72.8	Confident	4 Å²	4	33.3 Å²	33.3	2%	0.021	16%	0.16	C	C	.	.	H	α-helix	trans	-61.8	-42.4	178.2	-62.3	170.3	0	0	0	110.8	L2 V160 I209 E210 G216 Y222	L2-I213 HydrophobicContact CD2-CD1 4.38Å; L2-I213 HydrophobicContact CD2-CG2 3.8Å; V160-I213 HydrophobicContact CG1-CG1 4.41Å; V160-I213 HydrophobicContact CG2-CG1 3.93Å; I209-I213 HydrophobicContact CG2-CD1 3.81Å; I209-I213 HydrophobicContact CG2-CG1 4.32Å; I209-I213 WeakPolarHBondContact O-CG1 3.4Å; I209-I213 PolarHBondContact O-N 2.97Å; E210-I213 PolarHBondContact O-N 3Å; I213-G216 PolarHBondContact O-N 3.43Å; I213-Y222 HydrophobicContact CB-CD2 4.39Å; I213-Y222 HydrophobicContact CB-CE2 4.06Å; I213-Y222 HydrophobicContact CG2-CD2 3.53Å; I213-Y222 HydrophobicContact CG2-CE1 4.47Å; I213-Y222 HydrophobicContact CG2-CE2 3.41Å; I213-Y222 VanDerWaalsContact CG2-CE2 3.41Å; I213-Y222 HydrophobicContact CG2-CG 4.17Å
214	L	76.3	Confident	71.9	Confident	0 Å²	0	40.3 Å²	40.3	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-61.4	-48.3	173.7	-90.6	-169.9	0	0	0	112.6	R39 F42 I43 V46 F149 E210 Q212 G216 Y222 A230 H234	R39-L214 PolarHBondContact NH1-O 3.4Å; R39-L214 VanDerWaalsContact NH1-O 3.1Å; F42-L214 HydrophobicContact CD1-CD2 4.17Å; F42-L214 HydrophobicContact CE1-CD2 3.56Å; I43-L214 HydrophobicContact CG1-CB 4.5Å; V46-L214 HydrophobicContact CG1-CD1 4.21Å; V46-L214 HydrophobicContact CG2-CD2 4.24Å; F149-L214 HydrophobicContact CE2-CB 4.23Å; F149-L214 HydrophobicContact CE2-CD1 3.65Å; F149-L214 HydrophobicContact CZ-CD1 4.21Å; E210-L214 PolarHBondContact O-N 3.12Å; Q212-L214 VanDerWaalsContact C-N 3.34Å; Q212-L214 PolarHBondContact O-N 2.98Å; L214-G216 PolarHBondContact O-N 2.62Å; L214-Y222 HydrophobicContact CD2-CD2 3.71Å; L214-Y222 HydrophobicContact CD2-CE2 4.03Å; L214-Y222 HydrophobicContact CG-CD2 4.19Å; L214-Y222 HydrophobicContact CG-CE2 4.16Å; L214-A230 HydrophobicContact CD2-CB 3.86Å; L214-H234 WeakPolarHBondContact CD1-CE1 3.44Å; L214-H234 WeakPolarHBondContact CD1-NE2 3.35Å; L214-H234 VanDerWaalsContact CG-CE1 3.46Å; L214-H234 WeakPolarHBondContact CG-CE1 3.43Å
215	Y	72.2	Confident	71.2	Confident	59 Å²	59	44.9 Å²	44.9	23%	0.231	21%	0.206	C	C	.	.	H	α-helix	trans	-72	-19.1	-177.7	-164.6	-101.6	0	0	0	113.1	L31 I35 R39 I43 I153 A211 Q212	L31-Y215 HydrophobicContact CD2-CD1 4.43Å; L31-Y215 HydrophobicContact CD2-CE1 4.26Å; I35-Y215 HydrophobicContact CD1-CE2 4.38Å; I35-Y215 HydrophobicContact CG2-CE2 4.48Å; R39-Y215 WeakPolarHBondContact CD-O 3.4Å; R39-Y215 VanDerWaalsContact NH1-C 3.32Å; R39-Y215 PolarHBondContact NH1-O 3.23Å; I43-Y215 HydrophobicContact CD1-CD2 4.12Å; I153-Y215 HydrophobicContact CB-CG 4.44Å; I153-Y215 HydrophobicContact CD1-CD2 3.71Å; I153-Y215 HydrophobicContact CD1-CE2 4.38Å; I153-Y215 HydrophobicContact CD1-CG 4.19Å; I153-Y215 HydrophobicContact CG1-CD2 3.97Å; I153-Y215 HydrophobicContact CG1-CG 3.94Å; I153-Y215 HydrophobicContact CG2-CD1 3.91Å; I153-Y215 HydrophobicContact CG2-CD2 3.76Å; I153-Y215 HydrophobicContact CG2-CE1 3.91Å; I153-Y215 HydrophobicContact CG2-CE2 3.78Å; I153-Y215 HydrophobicContact CG2-CG 3.82Å; A211-Y215 WeakPolarHBondContact O-CB 3.23Å; A211-Y215 PolarHBondContact O-N 3.18Å; Q212-Y215 PolarHBondContact O-N 2.95Å
216	G	64.9	Low	70.4	Confident	28 Å²	28	44.4 Å²	44.4	29%	0.289	20%	0.202	S	C	.	.	T	Hydrogen-bonded Turn	trans	112.3	62.3	173.9	0	0	0	0	0	112.9	R39 Q212 I213 L214	R39-G216 VanDerWaalsContact NH1-N 3.12Å; Q212-G216 CarbonylContact O-C 3.53Å; Q212-G216 PolarHBondContact O-N 3.42Å; I213-G216 PolarHBondContact O-N 3.43Å; L214-G216 PolarHBondContact O-N 2.62Å
217	G	61.7	Low	69.8	Low	9 Å²	9	46.2 Å²	46.2	9%	0.093	21%	0.208	C	C	.	.			trans	-51.6	152.8	174.3	0	0	0	0	0	112.3	Q212	Q212-G217 PolarHBondContact O-N 3.14Å
218	R	62.1	Low	69.1	Low	138 Å²	138	47.2 Å²	47.2	52%	0.521	21%	0.212	S	C	.	.	S	Bend	trans	-69.9	-41.1	-174.9	-63.3	179.8	177.3	-170.5	-3.7	110.9	Y5 D158	Y5-R218 WeakPolarHBondContact CD2-O 3.4Å; Y5-R218 WeakPolarHBondContact CE2-O 3.32Å; D158-R218 WeakPolarHBondContact OD2-CB 3.26Å
219	E	60.3	Low	68.4	Low	72 Å²	72	46.8 Å²	46.8	34%	0.336	21%	0.209	S	C	.	.	S	Bend	trans	-87.7	-35.8	-179.7	-73.9	-164.1	175.6	0	0	114.6	D158 V160 S161	D158-E219 PolarHBondContact OD2-N 3.49Å; V160-E219 HydrophobicContact CG1-CB 4.11Å; S161-E219 WeakPolarHBondContact CA-OE2 3.4Å
220	M	60.5	Low	68	Low	25 Å²	25	46.2 Å²	46.2	12%	0.123	21%	0.206	C	C	.	.			trans	-141.3	137.8	-176	-50.4	-169.8	-80.7	0	0	111.4	L2 V160 F163	L2-M220 HydrophobicContact CB-CB 4.19Å; L2-M220 HydrophobicContact CB-CG 4.27Å; L2-M220 HydrophobicContact CB-SD 3.81Å; L2-M220 HydrophobicContact CD1-SD 3.84Å; L2-M220 HydrophobicContact CD2-CB 3.56Å; L2-M220 HydrophobicContact CD2-CG 4.4Å; L2-M220 HydrophobicContact CD2-SD 4.23Å; L2-M220 HydrophobicContact CG-CB 4.36Å; L2-M220 HydrophobicContact CG-SD 4.14Å; V160-M220 HydrophobicContact CG1-CB 3.54Å; V160-M220 HydrophobicContact CG1-CE 3.3Å; V160-M220 HydrophobicContact CG1-CG 3.62Å; V160-M220 HydrophobicContact CG1-SD 4.3Å; F163-M220 HydrophobicContact CB-CE 3.45Å; F163-M220 VanDerWaalsContact CB-CE 3.45Å; F163-M220 HydrophobicContact CD1-CE 3.82Å; F163-M220 HydrophobicContact CD2-CE 3.76Å; F163-M220 HydrophobicContact CE1-CE 4.48Å; F163-M220 HydrophobicContact CE2-CE 4.42Å; F163-M220 HydrophobicContact CG-CE 3.41Å; F163-M220 VanDerWaalsContact CG-CE 3.41Å
221	Y	67.4	Low	67.7	Low	62 Å²	62	45.8 Å²	45.8	24%	0.243	20%	0.204	C	C	.	.			trans	-148.7	156.3	-179.2	63.6	-86.9	0	0	0	110.7	R223	Y221-R223 HydrophobicContact CE2-CG 4.43Å
222	Y	65	Low	67.4	Low	14 Å²	14	46.1 Å²	46.1	6%	0.055	21%	0.205	C	C	.	.			trans	-76.6	133.4	171.2	-70.3	-66.9	0	0	0	111.7	F42 E210 I213 L214 D226 F229 A230	F42-Y222 HydrophobicContact CZ-CG 4.47Å; E210-Y222 WeakPolarHBondContact OE1-CE2 3.3Å; E210-Y222 VanDerWaalsContact OE1-CZ 3.28Å; E210-Y222 PolarHBondContact OE1-OH 3Å; E210-Y222 PolarHBondContact OE2-OH 3.15Å; I213-Y222 HydrophobicContact CB-CD2 4.39Å; I213-Y222 HydrophobicContact CB-CE2 4.06Å; I213-Y222 HydrophobicContact CG2-CD2 3.53Å; I213-Y222 HydrophobicContact CG2-CE1 4.47Å; I213-Y222 HydrophobicContact CG2-CE2 3.41Å; I213-Y222 VanDerWaalsContact CG2-CE2 3.41Å; I213-Y222 HydrophobicContact CG2-CG 4.17Å; L214-Y222 HydrophobicContact CD2-CD2 3.71Å; L214-Y222 HydrophobicContact CD2-CE2 4.03Å; L214-Y222 HydrophobicContact CG-CD2 4.19Å; L214-Y222 HydrophobicContact CG-CE2 4.16Å; Y222-D226 HydrophobicContact CD1-CB 3.88Å; Y222-F229 HydrophobicContact CD1-CD1 4.11Å; Y222-F229 AromaticContact CE1-CD1 3.42Å; Y222-F229 HydrophobicContact CE1-CD1 3.42Å; Y222-F229 VanDerWaalsContact CE1-CD1 3.42Å; Y222-F229 AromaticContact CE1-CE1 3.68Å; Y222-F229 HydrophobicContact CE1-CE1 3.68Å; Y222-F229 HydrophobicContact CE1-CG 4.41Å; Y222-A230 HydrophobicContact CD1-CB 3.95Å; Y222-A230 HydrophobicContact CD2-CB 3.81Å; Y222-A230 HydrophobicContact CE1-CB 3.95Å; Y222-A230 HydrophobicContact CE2-CB 3.79Å; Y222-A230 HydrophobicContact CG-CB 3.87Å
223	R	64	Low	67.2	Low	95 Å²	95	46.9 Å²	46.9	36%	0.358	21%	0.211	S	C	.	.			trans	-72	158.4	162.6	-64.8	-177.3	172.2	-170.7	-3.2	109.1	H3 Y221 E225 D226	H3-R223 PolarHBondContact CD2-NE 2.95Å; H3-R223 PolarHBondContact CD2-NH2 3.1Å; H3-R223 PolarHBondContact CE1-NH2 3.49Å; H3-R223 VanDerWaalsContact CE1-NH2 3.31Å; H3-R223 PolarHBondContact NE2-NE 3.17Å; H3-R223 PolarHBondContact NE2-NH2 3.1Å; Y221-R223 HydrophobicContact CE2-CG 4.43Å; R223-E225 PolarHBondContact O-N 3.32Å; R223-D226 WeakPolarHBondContact CB-OD2 3.44Å; R223-D226 PolarHBondContact N-OD2 3.06Å; R223-D226 WeakPolarHBondContact O-CB 3.3Å; R223-D226 PolarHBondContact O-N 3.27Å
224	R	63.7	Low	67.3	Low	148 Å²	148	47.2 Å²	47.2	56%	0.558	21%	0.213	S	C	*	.	G	3₁₀ helix	trans	-58.8	-31.2	176.9	-67.2	-177	-178.2	148.3	8.1	112.8	D36 D226	D36-R224 IonicContact OD2-NH2 2.99Å; D36-R224 PolarHBondContact OD2-NH2 3.29Å; R224-D226 VanDerWaalsContact C-N 3.27Å
225	E	65.2	Low	67.2	Low	167 Å²	167	47.4 Å²	47.4	78%	0.78	21%	0.213	S	C	*	.	G	3₁₀ helix	trans	-70.2	-24	176.5	-64.9	166.4	-167.2	0	0	112.1	R223 F227	R223-E225 PolarHBondContact O-N 3.32Å; E225-F227 PolarHBondContact O-N 3.06Å; E225-F227 VanDerWaalsContact O-N 3.14Å
226	D	65	Low	67.3	Low	23 Å²	23	46.9 Å²	46.9	12%	0.123	21%	0.212	C	C	.	.	G	3₁₀ helix	trans	-82.4	18.6	179.8	-59.4	-46.3	0	0	0	112.6	M1 Y222 R223 R224 I228 F229 A230	M1-D226 PolarHBondContact N-OD1 2.99Å; M1-D226 PolarHBondContact N-OD2 3.2Å; Y222-D226 HydrophobicContact CD1-CB 3.88Å; R223-D226 WeakPolarHBondContact CB-OD2 3.44Å; R223-D226 PolarHBondContact N-OD2 3.06Å; R223-D226 WeakPolarHBondContact O-CB 3.3Å; R223-D226 PolarHBondContact O-N 3.27Å; R224-D226 VanDerWaalsContact C-N 3.27Å; D226-I228 VanDerWaalsContact C-N 3.32Å; D226-I228 PolarHBondContact O-N 3.42Å; D226-F229 HydrophobicContact CB-CB 4.46Å; D226-F229 WeakPolarHBondContact O-CB 3.31Å; D226-F229 PolarHBondContact O-N 3.48Å; D226-A230 PolarHBondContact O-N 3.44Å
227	F	69.3	Low	67.8	Low	49 Å²	49	46.3 Å²	46.3	22%	0.215	20%	0.203	C	C	.	.	H	α-helix	trans	-52.5	-49.7	-178.6	167.9	-111.2	0	0	0	112.6	F42 K45 V46 T49 E225 F229 A230 S231	F42-F227 HydrophobicContact CD2-CB 4.3Å; F42-F227 HydrophobicContact CD2-CD2 4.32Å; F42-F227 HydrophobicContact CE2-CB 3.63Å; F42-F227 HydrophobicContact CE2-CD2 4.11Å; F42-F227 HydrophobicContact CE2-CG 4.39Å; F42-F227 HydrophobicContact CZ-CB 4.43Å; K45-F227 VanDerWaalsContact C-CE2 3.45Å; K45-F227 HydrophobicContact CB-CD2 4.07Å; K45-F227 HydrophobicContact CB-CE2 3.35Å; K45-F227 HydrophobicContact CB-CZ 3.81Å; V46-F227 HydrophobicContact CB-CE2 4.35Å; V46-F227 HydrophobicContact CG2-CD2 3.7Å; V46-F227 HydrophobicContact CG2-CE2 3.62Å; T49-F227 HydrophobicContact CG2-CE1 4.34Å; T49-F227 HydrophobicContact CG2-CZ 3.73Å; E225-F227 PolarHBondContact O-N 3.06Å; E225-F227 VanDerWaalsContact O-N 3.14Å; F227-F229 VanDerWaalsContact C-N 3.28Å; F227-F229 PolarHBondContact O-N 2.83Å; F227-A230 PolarHBondContact O-N 3.17Å; F227-S231 PolarHBondContact O-N 2.8Å; F227-S231 PolarHBondContact O-OG 3.12Å
228	I	66.1	Low	68.6	Low	36 Å²	36	46.3 Å²	46.3	19%	0.185	20%	0.201	C	C	.	.	H	α-helix	trans	-62.3	-42.7	-177.4	-65.5	176.1	0	0	0	109.6	D108 Y111 D226 S231 L232	D108-I228 WeakPolarHBondContact OD1-CD1 3.16Å; Y111-I228 HydrophobicContact CD2-CG2 3.45Å; Y111-I228 VanDerWaalsContact CD2-CG2 3.45Å; Y111-I228 HydrophobicContact CE2-CG2 4.13Å; Y111-I228 HydrophobicContact CG-CG2 3.7Å; D226-I228 VanDerWaalsContact C-N 3.32Å; D226-I228 PolarHBondContact O-N 3.42Å; I228-S231 PolarHBondContact O-N 3.09Å; I228-S231 PolarHBondContact O-OG 3.18Å; I228-L232 HydrophobicContact CG2-CD1 4.33Å; I228-L232 WeakPolarHBondContact O-CG 3.01Å; I228-L232 PolarHBondContact O-N 3.25Å
229	F	67.8	Low	69.2	Low	19 Å²	19	40.3 Å²	40.3	8%	0.083	18%	0.179	C	C	.	.	H	α-helix	trans	-63.2	-48.9	177	-177	-130.4	0	0	0	112.6	F95 Y222 D226 F227 S231 L232 V233	F95-F229 HydrophobicContact CD2-CE2 4.07Å; F95-F229 AromaticContact CD2-CZ 3.67Å; F95-F229 HydrophobicContact CD2-CZ 3.67Å; F95-F229 AromaticContact CE2-CZ 3.97Å; F95-F229 HydrophobicContact CE2-CZ 3.97Å; Y222-F229 HydrophobicContact CD1-CD1 4.11Å; Y222-F229 AromaticContact CE1-CD1 3.42Å; Y222-F229 HydrophobicContact CE1-CD1 3.42Å; Y222-F229 VanDerWaalsContact CE1-CD1 3.42Å; Y222-F229 AromaticContact CE1-CE1 3.68Å; Y222-F229 HydrophobicContact CE1-CE1 3.68Å; Y222-F229 HydrophobicContact CE1-CG 4.41Å; D226-F229 HydrophobicContact CB-CB 4.46Å; D226-F229 WeakPolarHBondContact O-CB 3.31Å; D226-F229 PolarHBondContact O-N 3.48Å; F227-F229 VanDerWaalsContact C-N 3.28Å; F227-F229 PolarHBondContact O-N 2.83Å; F229-S231 PolarHBondContact O-N 3.05Å; F229-L232 WeakPolarHBondContact O-CB 3.36Å; F229-L232 PolarHBondContact O-N 3.2Å; F229-V233 HydrophobicContact CD2-CG2 4.02Å; F229-V233 HydrophobicContact CE1-CG2 4.24Å; F229-V233 HydrophobicContact CE2-CG2 3.62Å; F229-V233 HydrophobicContact CZ-CG2 3.71Å; F229-V233 WeakPolarHBondContact O-CG2 3.38Å; F229-V233 PolarHBondContact O-N 3.1Å
230	A	70.3	Confident	69.9	Low	0 Å²	0	38.1 Å²	38.1	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-58.2	-39.1	177.9	0	0	0	0	0	111.6	F42 V46 L214 Y222 D226 F227 H234	F42-A230 HydrophobicContact CE1-CB 4.25Å; F42-A230 HydrophobicContact CZ-CB 3.98Å; V46-A230 HydrophobicContact CG2-CB 4.01Å; L214-A230 HydrophobicContact CD2-CB 3.86Å; Y222-A230 HydrophobicContact CD1-CB 3.95Å; Y222-A230 HydrophobicContact CD2-CB 3.81Å; Y222-A230 HydrophobicContact CE1-CB 3.95Å; Y222-A230 HydrophobicContact CE2-CB 3.79Å; Y222-A230 HydrophobicContact CG-CB 3.87Å; D226-A230 PolarHBondContact O-N 3.44Å; F227-A230 PolarHBondContact O-N 3.17Å; A230-H234 PolarHBondContact O-N 3.01Å; A230-H234 VanDerWaalsContact O-N 3.13Å; A230-H234 PolarHBondContact O-ND1 3.13Å
231	S	72.5	Confident	70.8	Confident	0 Å²	0	37.1 Å²	37.1	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-67.1	-38.6	175	74.4	0	0	0	0	113.3	T49 N50 Y111 F227 I228 F229 H234 L235	T49-S231 WeakPolarHBondContact OG1-CB 3.28Å; N50-S231 PolarHBondContact OD1-O 3.4Å; Y111-S231 WeakPolarHBondContact CE2-OG 3.26Å; Y111-S231 PolarHBondContact OH-OG 3.21Å; F227-S231 PolarHBondContact O-N 2.8Å; F227-S231 PolarHBondContact O-OG 3.12Å; I228-S231 PolarHBondContact O-N 3.09Å; I228-S231 PolarHBondContact O-OG 3.18Å; F229-S231 PolarHBondContact O-N 3.05Å; S231-H234 PolarHBondContact O-N 3.38Å; S231-L235 WeakPolarHBondContact O-CB 3.16Å; S231-L235 PolarHBondContact O-N 3.16Å
232	L	70.9	Confident	71.4	Confident	6 Å²	6	34.1 Å²	34.1	3%	0.031	15%	0.152	C	C	.	.	H	α-helix	trans	-65.9	-42.8	175.5	-76	171.7	0	0	0	112.5	I94 Y111 F114 I228 F229 H234 L235 F236	I94-L232 HydrophobicContact CD1-CD1 3.93Å; I94-L232 HydrophobicContact CG2-CD1 3.89Å; Y111-L232 HydrophobicContact CD2-CD1 3.86Å; Y111-L232 HydrophobicContact CD2-CD2 3.37Å; Y111-L232 HydrophobicContact CD2-CG 3.41Å; Y111-L232 VanDerWaalsContact CD2-CG 3.41Å; Y111-L232 HydrophobicContact CE2-CD2 3.62Å; Y111-L232 HydrophobicContact CE2-CG 3.64Å; Y111-L232 HydrophobicContact CG-CD2 4.49Å; F114-L232 HydrophobicContact CB-CD2 4.18Å; I228-L232 HydrophobicContact CG2-CD1 4.33Å; I228-L232 WeakPolarHBondContact O-CG 3.01Å; I228-L232 PolarHBondContact O-N 3.25Å; F229-L232 WeakPolarHBondContact O-CB 3.36Å; F229-L232 PolarHBondContact O-N 3.2Å; L232-H234 VanDerWaalsContact C-N 3.34Å; L232-L235 PolarHBondContact O-N 3.32Å; L232-F236 WeakPolarHBondContact O-CB 3.24Å; L232-F236 PolarHBondContact O-N 2.79Å
233	V	72.3	Confident	71.8	Confident	30 Å²	30	34.4 Å²	34.4	18%	0.182	16%	0.156	C	C	.	.	H	α-helix	trans	-62.4	-46	178.6	175.2	0	0	0	0	109.9	E210 F229 L235 F236 L237	E210-V233 HydrophobicContact CG-CG1 4.01Å; F229-V233 HydrophobicContact CD2-CG2 4.02Å; F229-V233 HydrophobicContact CE1-CG2 4.24Å; F229-V233 HydrophobicContact CE2-CG2 3.62Å; F229-V233 HydrophobicContact CZ-CG2 3.71Å; F229-V233 WeakPolarHBondContact O-CG2 3.38Å; F229-V233 PolarHBondContact O-N 3.1Å; V233-L235 PolarHBondContact O-N 3.03Å; V233-F236 WeakPolarHBondContact O-CB 3.44Å; V233-F236 PolarHBondContact O-N 2.67Å; V233-L237 HydrophobicContact CG1-CD1 4.27Å; V233-L237 WeakPolarHBondContact O-CG 3.48Å; V233-L237 PolarHBondContact O-N 3.26Å
234	H	75.9	Confident	72.2	Confident	12 Å²	12	29.9 Å²	29.9	6%	0.056	14%	0.139	C	C	.	.	H	α-helix	trans	-63.1	-43	175.7	-81.8	71	0	0	0	112.9	V46 N50 E210 L214 A230 S231 L232 F236 L237 L238	V46-H234 HydrophobicContact CG1-CB 4.32Å; N50-H234 WeakPolarHBondContact ND2-CB 3.39Å; E210-H234 VanDerWaalsContact CD-CE1 3.48Å; E210-H234 WeakPolarHBondContact CG-CE1 3.41Å; E210-H234 IonicContact OE1-CE1 3.88Å; E210-H234 PolarHBondContact OE1-CE1 2.94Å; E210-H234 IonicContact OE1-ND1 4Å; E210-H234 PolarHBondContact OE1-ND1 3.01Å; L214-H234 WeakPolarHBondContact CD1-CE1 3.44Å; L214-H234 WeakPolarHBondContact CD1-NE2 3.35Å; L214-H234 VanDerWaalsContact CG-CE1 3.46Å; L214-H234 WeakPolarHBondContact CG-CE1 3.43Å; A230-H234 PolarHBondContact O-N 3.01Å; A230-H234 VanDerWaalsContact O-N 3.13Å; A230-H234 PolarHBondContact O-ND1 3.13Å; S231-H234 PolarHBondContact O-N 3.38Å; L232-H234 VanDerWaalsContact C-N 3.34Å; H234-F236 VanDerWaalsContact C-N 3.29Å; H234-F236 PolarHBondContact O-N 3.01Å; H234-L237 PolarHBondContact O-N 2.71Å; H234-L238 VanDerWaalsContact O-CB 3.29Å; H234-L238 WeakPolarHBondContact O-CB 3.35Å; H234-L238 PolarHBondContact O-N 3.29Å
235	L	73.8	Confident	72.8	Confident	3 Å²	3	24.2 Å²	24.2	2%	0.016	12%	0.119	C	C	.	.	H	α-helix	trans	-59.4	-44	176.8	172.1	54.5	0	0	0	111.4	Q53 F118 S231 L232 V233 L238 T239	Q53-L235 HydrophobicContact CB-CD1 4.21Å; Q53-L235 HydrophobicContact CG-CD1 3.5Å; Q53-L235 VanDerWaalsContact CG-CD1 3.5Å; Q53-L235 HydrophobicContact CG-CD2 4.26Å; F118-L235 HydrophobicContact CD2-CD2 3.95Å; F118-L235 HydrophobicContact CD2-CG 4.34Å; F118-L235 HydrophobicContact CG-CD2 4.46Å; S231-L235 WeakPolarHBondContact O-CB 3.16Å; S231-L235 PolarHBondContact O-N 3.16Å; L232-L235 PolarHBondContact O-N 3.32Å; V233-L235 PolarHBondContact O-N 3.03Å; L235-L238 PolarHBondContact O-N 3.21Å; L235-T239 WeakPolarHBondContact O-CB 3.45Å; L235-T239 PolarHBondContact O-N 3.46Å; L235-T239 PolarHBondContact O-OG1 3.21Å
236	F	73.7	Confident	73.1	Confident	49 Å²	49	16.7 Å²	16.7	22%	0.215	8%	0.084	C	C	.	.	H	α-helix	trans	-59.9	-50.4	176.3	175.3	-99.3	0	0	0	111	M88 T91 F118 L232 V233 H234 L238 T239 F240	M88-F236 HydrophobicContact CG-CE2 4.46Å; T91-F236 HydrophobicContact CG2-CB 3.89Å; T91-F236 HydrophobicContact CG2-CD1 4.44Å; T91-F236 HydrophobicContact CG2-CD2 3.61Å; T91-F236 HydrophobicContact CG2-CE2 4.23Å; T91-F236 HydrophobicContact CG2-CG 3.72Å; T91-F236 VanDerWaalsContact OG1-CD2 3.32Å; T91-F236 WeakPolarHBondContact OG1-CD2 3.48Å; F118-F236 HydrophobicContact CE1-CD2 4.39Å; F118-F236 HydrophobicContact CZ-CD2 4.24Å; L232-F236 WeakPolarHBondContact O-CB 3.24Å; L232-F236 PolarHBondContact O-N 2.79Å; V233-F236 WeakPolarHBondContact O-CB 3.44Å; V233-F236 PolarHBondContact O-N 2.67Å; H234-F236 VanDerWaalsContact C-N 3.29Å; H234-F236 PolarHBondContact O-N 3.01Å; F236-L238 VanDerWaalsContact C-N 3.3Å; F236-L238 PolarHBondContact O-N 3.41Å; F236-T239 PolarHBondContact O-N 2.97Å; F236-F240 HydrophobicContact CE2-CD2 4.44Å; F236-F240 HydrophobicContact CZ-CD2 4.19Å; F236-F240 HydrophobicContact CZ-CE2 4.48Å; F236-F240 HydrophobicContact CZ-CG 4.48Å; F236-F240 WeakPolarHBondContact O-CB 3.17Å; F236-F240 PolarHBondContact O-N 3.31Å
237	L	77.2	Confident	73.3	Confident	16 Å²	16	17.5 Å²	17.5	8%	0.084	9%	0.089	C	C	.	.	H	α-helix	trans	-59.8	-41.3	179.1	-69.1	175.6	0	0	0	112.6	A206 E210 V233 H234 F240 S241	A206-L237 HydrophobicContact CB-CD1 4.4Å; A206-L237 HydrophobicContact CB-CD2 3.45Å; A206-L237 VanDerWaalsContact CB-CD2 3.45Å; E210-L237 HydrophobicContact CB-CD1 3.95Å; E210-L237 HydrophobicContact CG-CD1 3.97Å; V233-L237 HydrophobicContact CG1-CD1 4.27Å; V233-L237 WeakPolarHBondContact O-CG 3.48Å; V233-L237 PolarHBondContact O-N 3.26Å; H234-L237 PolarHBondContact O-N 2.71Å; L237-F240 PolarHBondContact O-N 2.94Å; L237-S241 VanDerWaalsContact O-CB 3.32Å; L237-S241 WeakPolarHBondContact O-CB 3.4Å; L237-S241 PolarHBondContact O-N 2.83Å
238	L	78.4	Confident	73.2	Confident	9 Å²	9	20.1 Å²	20.1	5%	0.047	10%	0.099	C	C	.	.	H	α-helix	trans	-64.5	-46.4	177.1	-173.3	82.7	0	0	0	111.5	I54 W138 T141 H234 L235 F236 F240 S241 Y242	I54-L238 HydrophobicContact CD1-CD1 4.41Å; I54-L238 HydrophobicContact CD1-CD2 3.56Å; I54-L238 HydrophobicContact CG1-CD2 3.43Å; I54-L238 VanDerWaalsContact CG1-CD2 3.43Å; W138-L238 HydrophobicContact CZ3-CD2 4.1Å; W138-L238 HydrophobicContact CZ3-CG 4.23Å; T141-L238 HydrophobicContact CG2-CD1 3.56Å; T141-L238 HydrophobicContact CG2-CG 3.95Å; T141-L238 WeakPolarHBondContact CG2-O 3.49Å; H234-L238 VanDerWaalsContact O-CB 3.29Å; H234-L238 WeakPolarHBondContact O-CB 3.35Å; H234-L238 PolarHBondContact O-N 3.29Å; L235-L238 PolarHBondContact O-N 3.21Å; F236-L238 VanDerWaalsContact C-N 3.3Å; F236-L238 PolarHBondContact O-N 3.41Å; L238-F240 VanDerWaalsContact C-N 3.33Å; L238-F240 PolarHBondContact O-N 3.31Å; L238-S241 WeakPolarHBondContact O-CB 3.49Å; L238-S241 PolarHBondContact O-N 3.07Å; L238-Y242 WeakPolarHBondContact O-CB 3.35Å; L238-Y242 PolarHBondContact O-N 3.45Å
239	T	73.9	Confident	73	Confident	11 Å²	11	19 Å²	19	7%	0.067	9%	0.094	C	C	.	.	H	α-helix	trans	-66	-38.4	178.9	-53.8	0	0	0	0	111.4	F118 I122 L235 F236 Y242 S243	F118-T239 HydrophobicContact CD1-CG2 3.91Å; F118-T239 HydrophobicContact CE1-CG2 4.39Å; I122-T239 HydrophobicContact CD1-CG2 3.73Å; I122-T239 HydrophobicContact CG1-CG2 3.66Å; L235-T239 WeakPolarHBondContact O-CB 3.45Å; L235-T239 PolarHBondContact O-N 3.46Å; L235-T239 PolarHBondContact O-OG1 3.21Å; F236-T239 PolarHBondContact O-N 2.97Å; T239-Y242 WeakPolarHBondContact O-CB 3.13Å; T239-Y242 PolarHBondContact O-N 3.38Å; T239-S243 PolarHBondContact O-N 3.3Å
240	F	74.4	Confident	72.4	Confident	26 Å²	26	23.2 Å²	23.2	11%	0.114	11%	0.112	C	C	.	.	H	α-helix	trans	-66.3	-40.3	176.1	-142.8	-118.8	0	0	0	110.8	M88 V199 I203 F236 L237 L238 Y242 S243 G244	M88-F240 HydrophobicContact CE-CE2 3.51Å; M88-F240 HydrophobicContact CE-CZ 4.19Å; M88-F240 HydrophobicContact CG-CE2 4.29Å; M88-F240 HydrophobicContact SD-CE2 3.94Å; M88-F240 HydrophobicContact SD-CZ 4.43Å; V199-F240 HydrophobicContact CB-CE1 4.32Å; V199-F240 HydrophobicContact CG1-CD1 3.59Å; V199-F240 HydrophobicContact CG1-CE1 3.69Å; V199-F240 HydrophobicContact CG1-CG 4.2Å; V199-F240 HydrophobicContact CG1-CZ 4.41Å; V199-F240 WeakPolarHBondContact CG1-O 3.37Å; V199-F240 HydrophobicContact CG2-CE1 4.17Å; V199-F240 HydrophobicContact CG2-CZ 4.38Å; I203-F240 HydrophobicContact CD1-CB 3.83Å; I203-F240 HydrophobicContact CD1-CD1 3.67Å; I203-F240 HydrophobicContact CD1-CG 4.16Å; I203-F240 WeakPolarHBondContact CD1-O 3.48Å; I203-F240 HydrophobicContact CG1-CB 4.1Å; I203-F240 HydrophobicContact CG1-CD1 3.69Å; I203-F240 HydrophobicContact CG1-CG 4.37Å; F236-F240 HydrophobicContact CE2-CD2 4.44Å; F236-F240 HydrophobicContact CZ-CD2 4.19Å; F236-F240 HydrophobicContact CZ-CE2 4.48Å; F236-F240 HydrophobicContact CZ-CG 4.48Å; F236-F240 WeakPolarHBondContact O-CB 3.17Å; F236-F240 PolarHBondContact O-N 3.31Å; L237-F240 PolarHBondContact O-N 2.94Å; L238-F240 VanDerWaalsContact C-N 3.33Å; L238-F240 PolarHBondContact O-N 3.31Å; F240-Y242 VanDerWaalsContact C-N 3.34Å; F240-Y242 PolarHBondContact O-N 3.41Å; F240-S243 WeakPolarHBondContact CA-OG 3.41Å; F240-S243 PolarHBondContact O-N 3.48Å; F240-S243 PolarHBondContact O-OG 3.23Å; F240-G244 PolarHBondContact O-N 3.36Å
241	S	80.9	Confident	71.5	Confident	4 Å²	4	24.1 Å²	24.1	3%	0.028	12%	0.12	C	C	.	.	H	α-helix	trans	-59.2	-47.4	174	-173.3	0	0	0	0	111.2	L237 L238 S243 G244 F245	L237-S241 VanDerWaalsContact O-CB 3.32Å; L237-S241 WeakPolarHBondContact O-CB 3.4Å; L237-S241 PolarHBondContact O-N 2.83Å; L238-S241 WeakPolarHBondContact O-CB 3.49Å; L238-S241 PolarHBondContact O-N 3.07Å; S241-S243 VanDerWaalsContact C-N 3.33Å; S241-S243 PolarHBondContact O-N 2.91Å; S241-G244 PolarHBondContact O-N 3.4Å; S241-G244 VanDerWaalsContact O-N 3.13Å; S241-F245 VanDerWaalsContact O-CD2 3.24Å; S241-F245 WeakPolarHBondContact O-CD2 3.47Å; S241-F245 PolarHBondContact O-N 3.28Å
242	Y	78.2	Confident	70.3	Confident	0 Å²	0	25.5 Å²	25.5	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-56.9	-46.4	174.3	-176.7	-109.5	0	0	0	112.4	I122 S126 I134 W138 T141 L238 T239 F240 G244 F245 I246	I122-Y242 HydrophobicContact CG1-CD1 4.34Å; I122-Y242 HydrophobicContact CG2-CD1 4.07Å; I122-Y242 HydrophobicContact CG2-CE1 3.62Å; S126-Y242 PolarHBondContact OG-OH 3.36Å; S126-Y242 VanDerWaalsContact OG-OH 3.08Å; I134-Y242 WeakPolarHBondContact CG2-OH 3.38Å; I134-Y242 WeakPolarHBondContact O-CE2 3.27Å; I134-Y242 PolarHBondContact O-OH 3.48Å; W138-Y242 HydrophobicContact CB-CE2 4.2Å; W138-Y242 AromaticContact CD1-CE2 3.25Å; W138-Y242 AromaticContact CD1-CZ 3.6Å; W138-Y242 AromaticContact CD2-CD2 3.55Å; W138-Y242 HydrophobicContact CD2-CD2 3.55Å; W138-Y242 AromaticContact CD2-CE2 3.58Å; W138-Y242 HydrophobicContact CD2-CE2 3.58Å; W138-Y242 HydrophobicContact CD2-CG 4.24Å; W138-Y242 AromaticContact CE2-CD2 3.66Å; W138-Y242 AromaticContact CE2-CE2 3.51Å; W138-Y242 AromaticContact CE2-CZ 3.71Å; W138-Y242 AromaticContact CE3-CD2 3.92Å; W138-Y242 HydrophobicContact CE3-CD2 3.92Å; W138-Y242 HydrophobicContact CE3-CE2 4.4Å; W138-Y242 HydrophobicContact CE3-CG 4.41Å; W138-Y242 AromaticContact CG-CD2 3.83Å; W138-Y242 HydrophobicContact CG-CD2 3.83Å; W138-Y242 AromaticContact CG-CE2 3.44Å; W138-Y242 HydrophobicContact CG-CE2 3.44Å; W138-Y242 VanDerWaalsContact CG-CE2 3.44Å; W138-Y242 HydrophobicContact CH2-CD2 4.46Å; W138-Y242 HydrophobicContact CH2-CG 4.22Å; W138-Y242 HydrophobicContact CZ2-CD1 4.11Å; W138-Y242 HydrophobicContact CZ2-CD2 4.15Å; W138-Y242 HydrophobicContact CZ2-CE1 4.23Å; W138-Y242 HydrophobicContact CZ2-CE2 4.29Å; W138-Y242 HydrophobicContact CZ2-CG 4.04Å; W138-Y242 HydrophobicContact CZ3-CD2 4.34Å; W138-Y242 HydrophobicContact CZ3-CG 4.38Å; W138-Y242 AromaticContact NE1-CD2 3.94Å; W138-Y242 AromaticContact NE1-CE1 3.93Å; W138-Y242 AromaticContact NE1-CE2 3.28Å; W138-Y242 VanDerWaalsContact NE1-CE2 3.28Å; W138-Y242 AromaticContact NE1-CZ 3.24Å; W138-Y242 PolarHBondContact NE1-OH 2.91Å; T141-Y242 VanDerWaalsContact OG1-CA 3.28Å; T141-Y242 WeakPolarHBondContact OG1-CA 3.37Å; T141-Y242 PolarHBondContact OG1-N 3.31Å; L238-Y242 WeakPolarHBondContact O-CB 3.35Å; L238-Y242 PolarHBondContact O-N 3.45Å; T239-Y242 WeakPolarHBondContact O-CB 3.13Å; T239-Y242 PolarHBondContact O-N 3.38Å; F240-Y242 VanDerWaalsContact C-N 3.34Å; F240-Y242 PolarHBondContact O-N 3.41Å; Y242-G244 VanDerWaalsContact C-N 3.31Å; Y242-G244 PolarHBondContact O-N 3.13Å; Y242-F245 PolarHBondContact O-N 2.9Å; Y242-I246 HydrophobicContact CD1-CD1 3.9Å; Y242-I246 HydrophobicContact CD1-CG1 4.45Å; Y242-I246 HydrophobicContact CE1-CD1 3.14Å; Y242-I246 HydrophobicContact CE1-CG1 3.97Å; Y242-I246 HydrophobicContact CE2-CD1 4.19Å; Y242-I246 HydrophobicContact CE2-CG1 4.23Å; Y242-I246 PolarHBondContact O-N 2.84Å; Y242-I246 WeakPolarHBondContact OH-CD1 3.49Å
243	S	74.8	Confident	69.1	Low	20 Å²	20	27.7 Å²	27.7	14%	0.14	15%	0.147	C	C	.	.	H	α-helix	trans	-62.9	-36.4	177.1	78.3	0	0	0	0	113	T239 F240 S241 T247	T239-S243 PolarHBondContact O-N 3.3Å; F240-S243 WeakPolarHBondContact CA-OG 3.41Å; F240-S243 PolarHBondContact O-N 3.48Å; F240-S243 PolarHBondContact O-OG 3.23Å; S241-S243 VanDerWaalsContact C-N 3.33Å; S241-S243 PolarHBondContact O-N 2.91Å; S243-T247 WeakPolarHBondContact O-CB 3.38Å; S243-T247 PolarHBondContact O-N 3.37Å; S243-T247 PolarHBondContact O-OG1 3.38Å
244	G	72.6	Confident	67.7	Low	0 Å²	0	32.3 Å²	32.3	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-64.1	-45.3	175.6	0	0	0	0	0	111.8	G196 F240 S241 Y242 T247 Y248	G196-G244 WeakPolarHBondContact CA-O 3.33Å; F240-G244 PolarHBondContact O-N 3.36Å; S241-G244 PolarHBondContact O-N 3.4Å; S241-G244 VanDerWaalsContact O-N 3.13Å; Y242-G244 VanDerWaalsContact C-N 3.31Å; Y242-G244 PolarHBondContact O-N 3.13Å; G244-T247 PolarHBondContact O-N 3.29Å; G244-Y248 WeakPolarHBondContact O-CB 3.43Å; G244-Y248 PolarHBondContact O-N 2.93Å
245	F	76.1	Confident	65.9	Low	28 Å²	28	37.4 Å²	37.4	12%	0.123	20%	0.202	C	C	.	.	H	α-helix	trans	-66.4	-44.3	175.8	-77	-64.9	0	0	0	112.6	L140 T141 L144 L200 S241 Y242 T247 Y248 S249	L140-F245 HydrophobicContact CB-CD1 4.08Å; L140-F245 HydrophobicContact CB-CD2 4.2Å; L140-F245 HydrophobicContact CB-CE1 3.87Å; L140-F245 HydrophobicContact CB-CE2 3.99Å; L140-F245 HydrophobicContact CB-CG 4.24Å; L140-F245 HydrophobicContact CB-CZ 3.82Å; L140-F245 HydrophobicContact CD1-CD1 3.88Å; L140-F245 HydrophobicContact CD1-CE1 3.96Å; L140-F245 HydrophobicContact CG-CE1 4.47Å; T141-F245 WeakPolarHBondContact OG1-CD2 3.14Å; L144-F245 HydrophobicContact CB-CE2 4.4Å; L144-F245 HydrophobicContact CD2-CE2 3.77Å; L144-F245 HydrophobicContact CD2-CZ 3.85Å; L200-F245 HydrophobicContact CD1-CD1 4.4Å; L200-F245 HydrophobicContact CD1-CE1 4.1Å; L200-F245 HydrophobicContact CD1-CZ 4.3Å; L200-F245 HydrophobicContact CD2-CD2 4.25Å; L200-F245 HydrophobicContact CD2-CE2 3.96Å; L200-F245 HydrophobicContact CD2-CZ 4.2Å; S241-F245 VanDerWaalsContact O-CD2 3.24Å; S241-F245 WeakPolarHBondContact O-CD2 3.47Å; S241-F245 PolarHBondContact O-N 3.28Å; Y242-F245 PolarHBondContact O-N 2.9Å; F245-T247 VanDerWaalsContact C-N 3.32Å; F245-T247 PolarHBondContact O-N 3.49Å; F245-Y248 PolarHBondContact O-N 2.99Å; F245-S249 WeakPolarHBondContact O-CB 3.32Å; F245-S249 PolarHBondContact O-N 2.89Å; F245-S249 PolarHBondContact O-OG 3.4Å
246	I	72	Confident	64.1	Low	10 Å²	10	45.9 Å²	45.9	5%	0.051	24%	0.239	C	C	.	.	H	α-helix	trans	-55.1	-49.6	174.5	-86.6	-170.6	0	0	0	110.9	L125 V129 Y242 Y248 S249 F250	L125-I246 HydrophobicContact CB-CD1 4.37Å; V129-I246 HydrophobicContact CG2-CG1 4.42Å; V129-I246 HydrophobicContact CG2-CG2 3.77Å; Y242-I246 HydrophobicContact CD1-CD1 3.9Å; Y242-I246 HydrophobicContact CD1-CG1 4.45Å; Y242-I246 HydrophobicContact CE1-CD1 3.14Å; Y242-I246 HydrophobicContact CE1-CG1 3.97Å; Y242-I246 HydrophobicContact CE2-CD1 4.19Å; Y242-I246 HydrophobicContact CE2-CG1 4.23Å; Y242-I246 PolarHBondContact O-N 2.84Å; Y242-I246 WeakPolarHBondContact OH-CD1 3.49Å; I246-Y248 VanDerWaalsContact C-N 3.3Å; I246-Y248 PolarHBondContact O-N 3.4Å; I246-S249 PolarHBondContact O-N 3.19Å; I246-F250 WeakPolarHBondContact O-CB 2.87Å; I246-F250 PolarHBondContact O-N 2.9Å
247	T	67.6	Low	62.5	Low	39 Å²	39	49 Å²	49	24%	0.239	26%	0.257	C	S	.	.	H	α-helix	trans	-66.2	-37.3	-176.2	-52	0	0	0	0	110.8	I195 S243 G244 F245 A251	I195-T247 HydrophobicContact CB-CG2 4.13Å; I195-T247 HydrophobicContact CG2-CG2 4.06Å; S243-T247 WeakPolarHBondContact O-CB 3.38Å; S243-T247 PolarHBondContact O-N 3.37Å; S243-T247 PolarHBondContact O-OG1 3.38Å; G244-T247 PolarHBondContact O-N 3.29Å; F245-T247 VanDerWaalsContact C-N 3.32Å; F245-T247 PolarHBondContact O-N 3.49Å; T247-A251 PolarHBondContact O-N 3.16Å
248	Y	67.8	Low	60.7	Low	105 Å²	105	54.4 Å²	54.4	41%	0.412	30%	0.296	S	S	.	.	H	α-helix	trans	-67.3	-42.8	174.5	-173.2	-102.9	0	0	0	112.5	P197 G244 F245 I246 A251 G252	P197-Y248 HydrophobicContact CG-CD2 3.78Å; P197-Y248 HydrophobicContact CG-CE2 3.97Å; G244-Y248 WeakPolarHBondContact O-CB 3.43Å; G244-Y248 PolarHBondContact O-N 2.93Å; F245-Y248 PolarHBondContact O-N 2.99Å; I246-Y248 VanDerWaalsContact C-N 3.3Å; I246-Y248 PolarHBondContact O-N 3.4Å; Y248-A251 PolarHBondContact O-N 2.82Å; Y248-G252 PolarHBondContact O-N 3.48Å
249	S	62.6	Low	59.3	Low	11 Å²	11	58 Å²	58	8%	0.077	31%	0.314	C	S	.	.	H	α-helix	trans	-65.3	-38.2	177.3	-68.1	0	0	0	0	112.5	F245 I246 A251 G252 V253	F245-S249 WeakPolarHBondContact O-CB 3.32Å; F245-S249 PolarHBondContact O-N 2.89Å; F245-S249 PolarHBondContact O-OG 3.4Å; I246-S249 PolarHBondContact O-N 3.19Å; S249-A251 PolarHBondContact O-N 3.12Å; S249-G252 PolarHBondContact O-N 2.93Å; S249-V253 PolarHBondContact O-N 3.25Å; S249-V253 VanDerWaalsContact O-N 3.12Å
250	F	54.5	Low	58.4	Low	109 Å²	109	62.7 Å²	62.7	48%	0.478	34%	0.34	S	S	.	.	H	α-helix	trans	-59.6	-33.3	174.4	-166.4	-95.6	0	0	0	112	I246	I246-F250 WeakPolarHBondContact O-CB 2.87Å; I246-F250 PolarHBondContact O-N 2.9Å
251	A	51.1	Low	57.5	Low	19 Å²	19	64.7 Å²	64.7	16%	0.157	35%	0.353	C	S	.	.	H	α-helix	trans	-81.4	-37.8	179.2	0	0	0	0	0	112.5	W193 T247 Y248 S249	W193-A251 HydrophobicContact CB-CB 4.26Å; W193-A251 HydrophobicContact CD2-CB 3.66Å; W193-A251 HydrophobicContact CE3-CB 4.3Å; W193-A251 HydrophobicContact CG-CB 3.61Å; W193-A251 WeakPolarHBondContact CZ2-O 3.46Å; W193-A251 PolarHBondContact NE1-O 3.3Å; T247-A251 PolarHBondContact O-N 3.16Å; Y248-A251 PolarHBondContact O-N 2.82Å; S249-A251 PolarHBondContact O-N 3.12Å
252	G	46.5	Very low	56.3	Low	29 Å²	29	71.1 Å²	71.1	30%	0.299	38%	0.383	S	S	.	.	H	α-helix	trans	-106.8	-11	-164.5	0	0	0	0	0	118.9	Y248 S249	Y248-G252 PolarHBondContact O-N 3.48Å; S249-G252 PolarHBondContact O-N 2.93Å
253	V	47.6	Very low	55.4	Low	51 Å²	51	72.1 Å²	72.1	31%	0.309	39%	0.393	S	S	.	.			trans	-144	52.4	-169	-152.3	0	0	0	0	114.6	F133 S249 T255	F133-V253 HydrophobicContact CD1-CB 4.31Å; F133-V253 HydrophobicContact CE1-CB 3.42Å; F133-V253 VanDerWaalsContact CE1-CB 3.42Å; F133-V253 HydrophobicContact CE1-CG1 3.47Å; F133-V253 VanDerWaalsContact CE1-CG1 3.47Å; F133-V253 HydrophobicContact CE1-CG2 3.9Å; F133-V253 HydrophobicContact CE2-CB 4.26Å; F133-V253 HydrophobicContact CE2-CG1 4.23Å; F133-V253 VanDerWaalsContact CE2-O 3.23Å; F133-V253 WeakPolarHBondContact CE2-O 3.42Å; F133-V253 HydrophobicContact CZ-CB 3.42Å; F133-V253 VanDerWaalsContact CZ-CB 3.42Å; F133-V253 HydrophobicContact CZ-CG1 3.18Å; F133-V253 HydrophobicContact CZ-CG2 4.38Å; F133-V253 WeakPolarHBondContact CZ-O 3.35Å; S249-V253 PolarHBondContact O-N 3.25Å; S249-V253 VanDerWaalsContact O-N 3.12Å; V253-T255 VanDerWaalsContact C-N 3.27Å
254	I	43.1	Very low	54.9	Low	128 Å²	128	71.7 Å²	71.7	66%	0.656	39%	0.389	S	S	*	.	S	Bend	trans	-84.2	5.2	167.4	-69.6	178.2	0	0	0	112.4
255	T	36.4	Very low	54.7	Low	118 Å²	118	72.5 Å²	72.5	72%	0.724	39%	0.393	S	S	*	.	S	Bend	trans	-124.1	4.7	-167.4	41.1	0	0	0	0	119.9	V253	V253-T255 VanDerWaalsContact C-N 3.27Å
256	F	36	Very low	54.3	Low	181 Å²	181	75.2 Å²	75.2	79%	0.794	41%	0.408	S	S	*	.	S	Bend	trans	-138.4	-0.5	-172.7	-107.5	-83.3	0	0	0	122.4
257	L	40.7	Very low	54.1	Low	115 Å²	115	78 Å²	78	60%	0.602	42%	0.42	S	S	*	.			trans	-143.5	79.3	176.5	-80.3	164.1	0	0	0	112	I259	L257-I259 HydrophobicContact CB-CG1 4.48Å; L257-I259 HydrophobicContact CD2-CD1 4.14Å; L257-I259 HydrophobicContact CD2-CG1 4.26Å; L257-I259 PolarHBondContact O-N 3.01Å
258	S	39.9	Very low	54.2	Low	129 Å²	129	76.1 Å²	76.1	90%	0.902	41%	0.408	S	S	*	.			trans	-74.1	83.7	162.6	67.3	0	0	0	0	108.6
259	I	49.2	Very low	54.6	Low	84 Å²	84	71.2 Å²	71.2	43%	0.431	39%	0.389	S	S	.	.			trans	-90.3	130.9	167	-56	-167.4	0	0	0	107.8	M132 L257	M132-I259 HydrophobicContact CE-CB 3.47Å; M132-I259 VanDerWaalsContact CE-CB 3.47Å; M132-I259 HydrophobicContact CE-CD1 3.61Å; M132-I259 HydrophobicContact CE-CG1 4.02Å; M132-I259 HydrophobicContact CE-CG2 3.33Å; M132-I259 HydrophobicContact SD-CB 4.14Å; M132-I259 HydrophobicContact SD-CD1 3.65Å; M132-I259 HydrophobicContact SD-CG1 4.2Å; L257-I259 HydrophobicContact CB-CG1 4.48Å; L257-I259 HydrophobicContact CD2-CD1 4.14Å; L257-I259 HydrophobicContact CD2-CG1 4.26Å; L257-I259 PolarHBondContact O-N 3.01Å
260	N	54	Low	55.2	Low	111 Å²	111	75.1 Å²	75.1	59%	0.594	40%	0.402	S	S	*	.			trans	-50.2	141.9	178.3	-160.8	5.5	0	0	0	110.5	E262 G263	N260-E262 PolarHBondContact O-N 3.14Å; N260-G263 WeakPolarHBondContact O-CA 3.49Å; N260-G263 PolarHBondContact O-N 3.4Å
261	V	55.2	Low	56.1	Low	67 Å²	67	70.7 Å²	70.7	41%	0.406	38%	0.383	S	S	.	.	H	α-helix	trans	-49.7	-34.3	-177	169.1	0	0	0	0	112.3	G263 M264 F265 L386	V261-G263 PolarHBondContact O-N 3.17Å; V261-M264 VanDerWaalsContact O-CB 3.3Å; V261-M264 WeakPolarHBondContact O-CB 3.43Å; V261-M264 PolarHBondContact O-N 2.95Å; V261-F265 HydrophobicContact CG1-CD2 4.15Å; V261-F265 HydrophobicContact CG1-CE2 3.66Å; V261-F265 VanDerWaalsContact O-CD2 3.31Å; V261-F265 WeakPolarHBondContact O-CD2 3.42Å; V261-F265 PolarHBondContact O-N 2.72Å; V261-L386 HydrophobicContact CG1-CD1 3.26Å; V261-L386 HydrophobicContact CG1-CG 4.5Å
262	E	56.8	Low	57.5	Low	139 Å²	139	69.8 Å²	69.8	65%	0.65	38%	0.376	S	S	*	.	H	α-helix	trans	-62.2	-37.9	175.5	-63.3	-178.2	164.5	0	0	113.3	N260 M264 F265 I266	N260-E262 PolarHBondContact O-N 3.14Å; E262-M264 VanDerWaalsContact C-N 3.27Å; E262-M264 PolarHBondContact O-N 3.33Å; E262-F265 PolarHBondContact O-N 3.34Å; E262-I266 PolarHBondContact O-N 3.3Å
263	G	59.1	Low	59.2	Low	21 Å²	21	68.4 Å²	68.4	22%	0.216	36%	0.362	C	S	.	.	H	α-helix	trans	-66.5	-30.2	175.9	0	0	0	0	0	112.6	N260 V261 F267	N260-G263 WeakPolarHBondContact O-CA 3.49Å; N260-G263 PolarHBondContact O-N 3.4Å; V261-G263 PolarHBondContact O-N 3.17Å; G263-F267 WeakPolarHBondContact O-CB 3.5Å; G263-F267 PolarHBondContact O-N 2.96Å; G263-F267 VanDerWaalsContact O-N 3.13Å
264	M	64.4	Low	60.7	Low	11 Å²	11	70.1 Å²	70.1	5%	0.054	37%	0.368	C	S	.	.	H	α-helix	trans	-65.4	-45.5	174	-170.2	-177.9	69.8	0	0	110.9	G131 F135 V261 E262 I266 F267 I268	G131-M264 VanDerWaalsContact CA-SD 3.58Å; F135-M264 HydrophobicContact CD2-CG 4.12Å; F135-M264 HydrophobicContact CE2-CG 3.62Å; F135-M264 HydrophobicContact CE2-SD 3.87Å; V261-M264 VanDerWaalsContact O-CB 3.3Å; V261-M264 WeakPolarHBondContact O-CB 3.43Å; V261-M264 PolarHBondContact O-N 2.95Å; E262-M264 VanDerWaalsContact C-N 3.27Å; E262-M264 PolarHBondContact O-N 3.33Å; M264-I266 PolarHBondContact O-N 3.48Å; M264-F267 WeakPolarHBondContact O-CB 3.41Å; M264-F267 PolarHBondContact O-N 3.5Å; M264-F267 VanDerWaalsContact O-N 3.17Å; M264-I268 HydrophobicContact CE-CD1 4.31Å; M264-I268 HydrophobicContact CG-CD1 3.95Å; M264-I268 HydrophobicContact CG-CG1 4.41Å; M264-I268 WeakPolarHBondContact O-CG1 3.28Å; M264-I268 PolarHBondContact O-N 3.37Å
265	F	67.6	Low	62.2	Low	18 Å²	18	64.9 Å²	64.9	8%	0.079	34%	0.341	C	S	.	.	H	α-helix	trans	-65.4	-36.4	178.7	-72.7	-67.7	0	0	0	113.5	V261 E262 F267 I268 S269 F381 I384 L386	V261-F265 HydrophobicContact CG1-CD2 4.15Å; V261-F265 HydrophobicContact CG1-CE2 3.66Å; V261-F265 VanDerWaalsContact O-CD2 3.31Å; V261-F265 WeakPolarHBondContact O-CD2 3.42Å; V261-F265 PolarHBondContact O-N 2.72Å; E262-F265 PolarHBondContact O-N 3.34Å; F265-F267 VanDerWaalsContact C-N 3.32Å; F265-I268 HydrophobicContact CD1-CD1 4.19Å; F265-I268 PolarHBondContact O-N 2.91Å; F265-S269 WeakPolarHBondContact O-CB 3.35Å; F265-S269 PolarHBondContact O-N 3.19Å; F265-S269 PolarHBondContact O-OG 2.74Å; F265-F381 HydrophobicContact CB-CB 4.25Å; F265-F381 HydrophobicContact CD1-CB 3.8Å; F265-F381 HydrophobicContact CD1-CD1 4.24Å; F265-F381 AromaticContact CD1-CG 3.97Å; F265-F381 HydrophobicContact CD1-CG 3.97Å; F265-F381 HydrophobicContact CE1-CB 4.5Å; F265-F381 HydrophobicContact CE1-CD1 4.43Å; F265-F381 HydrophobicContact CG-CB 4.23Å; F265-I384 HydrophobicContact CE1-CD1 3.99Å; F265-I384 HydrophobicContact CE2-CG2 4.46Å; F265-I384 HydrophobicContact CZ-CB 4.38Å; F265-I384 HydrophobicContact CZ-CD1 4.24Å; F265-I384 HydrophobicContact CZ-CG2 3.99Å; F265-L386 HydrophobicContact CE2-CD1 3.72Å; F265-L386 HydrophobicContact CZ-CD1 3.8Å
266	I	68.3	Low	64.4	Low	85 Å²	85	59.7 Å²	59.7	44%	0.436	31%	0.309	S	S	.	.	H	α-helix	trans	-60.3	-45.5	172.4	-70.1	166.1	0	0	0	110.3	E262 M264 S269 W270 Y374	E262-I266 PolarHBondContact O-N 3.3Å; M264-I266 PolarHBondContact O-N 3.48Å; I266-S269 PolarHBondContact O-N 2.87Å; I266-W270 PolarHBondContact O-N 3.14Å; I266-W270 VanDerWaalsContact O-N 3.17Å; I266-Y374 VanDerWaalsContact CG2-OH 3.27Å; I266-Y374 WeakPolarHBondContact CG2-OH 3.35Å
267	F	68.4	Low	66.6	Low	68 Å²	68	51.8 Å²	51.8	30%	0.298	28%	0.276	S	S	.	.	H	α-helix	trans	-66.4	-43.9	179.4	-168.5	-112.8	0	0	0	112.7	F135 I139 G263 M264 F265 S269 W270 I271	F135-F267 HydrophobicContact CB-CD1 3.78Å; F135-F267 HydrophobicContact CB-CE1 3.57Å; F135-F267 HydrophobicContact CD2-CD1 4.46Å; F135-F267 HydrophobicContact CG-CD1 4.21Å; F135-F267 HydrophobicContact CG-CE1 4.47Å; I139-F267 HydrophobicContact CD1-CE1 3.86Å; I139-F267 HydrophobicContact CD1-CZ 3.45Å; I139-F267 VanDerWaalsContact CD1-CZ 3.45Å; G263-F267 WeakPolarHBondContact O-CB 3.5Å; G263-F267 PolarHBondContact O-N 2.96Å; G263-F267 VanDerWaalsContact O-N 3.13Å; M264-F267 WeakPolarHBondContact O-CB 3.41Å; M264-F267 PolarHBondContact O-N 3.5Å; M264-F267 VanDerWaalsContact O-N 3.17Å; F265-F267 VanDerWaalsContact C-N 3.32Å; F267-S269 VanDerWaalsContact C-N 3.3Å; F267-S269 PolarHBondContact O-N 3.43Å; F267-W270 PolarHBondContact O-N 2.88Å; F267-I271 HydrophobicContact CD1-CD1 3.68Å; F267-I271 HydrophobicContact CE1-CD1 3.39Å; F267-I271 HydrophobicContact CE1-CG1 4.36Å; F267-I271 HydrophobicContact CG-CD1 4.47Å; F267-I271 HydrophobicContact CZ-CD1 3.93Å; F267-I271 PolarHBondContact O-N 3.06Å
268	I	70.1	Confident	68.4	Low	0 Å²	0	49.5 Å²	49.5	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-56	-47.4	173.8	-69	168.6	0	0	0	110.7	A62 F135 M264 F265 W270 I271 L272 F381	A62-I268 HydrophobicContact CB-CG2 3.95Å; F135-I268 HydrophobicContact CD1-CG1 3.99Å; F135-I268 HydrophobicContact CD2-CG1 4.01Å; F135-I268 HydrophobicContact CE1-CD1 3.96Å; F135-I268 HydrophobicContact CE1-CG1 3.44Å; F135-I268 VanDerWaalsContact CE1-CG1 3.44Å; F135-I268 HydrophobicContact CE2-CD1 3.53Å; F135-I268 HydrophobicContact CE2-CG1 3.45Å; F135-I268 VanDerWaalsContact CE2-CG1 3.45Å; F135-I268 HydrophobicContact CG-CG1 4.28Å; F135-I268 HydrophobicContact CZ-CD1 3.21Å; F135-I268 HydrophobicContact CZ-CG1 3.16Å; M264-I268 HydrophobicContact CE-CD1 4.31Å; M264-I268 HydrophobicContact CG-CD1 3.95Å; M264-I268 HydrophobicContact CG-CG1 4.41Å; M264-I268 WeakPolarHBondContact O-CG1 3.28Å; M264-I268 PolarHBondContact O-N 3.37Å; F265-I268 HydrophobicContact CD1-CD1 4.19Å; F265-I268 PolarHBondContact O-N 2.91Å; I268-W270 VanDerWaalsContact C-N 3.28Å; I268-W270 PolarHBondContact O-N 2.65Å; I268-I271 PolarHBondContact O-N 3.44Å; I268-L272 HydrophobicContact CG2-CD1 3.67Å; I268-L272 HydrophobicContact CG2-CG 4.2Å; I268-L272 WeakPolarHBondContact O-CB 3.24Å; I268-L272 WeakPolarHBondContact O-CG 3.43Å; I268-L272 PolarHBondContact O-N 3.13Å; I268-F381 HydrophobicContact CG2-CE2 3.98Å; I268-F381 HydrophobicContact CG2-CZ 4.23Å
269	S	75.4	Confident	70.3	Confident	1 Å²	1	44 Å²	44	1%	0.007	23%	0.227	C	C	.	.	H	α-helix	trans	-58.9	-41.9	-179	-59.9	0	0	0	0	111.2	F265 I266 F267 T273 F381	F265-S269 WeakPolarHBondContact O-CB 3.35Å; F265-S269 PolarHBondContact O-N 3.19Å; F265-S269 PolarHBondContact O-OG 2.74Å; I266-S269 PolarHBondContact O-N 2.87Å; F267-S269 VanDerWaalsContact C-N 3.3Å; F267-S269 PolarHBondContact O-N 3.43Å; S269-T273 WeakPolarHBondContact O-CB 3.32Å; S269-T273 PolarHBondContact O-N 3.04Å; S269-T273 PolarHBondContact O-OG1 3.12Å; S269-F381 WeakPolarHBondContact OG-CD2 3.06Å
270	W	74.9	Confident	71.8	Confident	93 Å²	93	40.5 Å²	40.5	35%	0.352	21%	0.209	S	C	.	.	H	α-helix	trans	-65.2	-46.6	175.3	-88.9	115.4	0	0	0	113	I266 F267 I268 T273 I274 L370 Y374	I266-W270 PolarHBondContact O-N 3.14Å; I266-W270 VanDerWaalsContact O-N 3.17Å; F267-W270 PolarHBondContact O-N 2.88Å; I268-W270 VanDerWaalsContact C-N 3.28Å; I268-W270 PolarHBondContact O-N 2.65Å; W270-T273 WeakPolarHBondContact O-CB 3.23Å; W270-T273 PolarHBondContact O-N 3.43Å; W270-I274 VanDerWaalsContact O-CG1 3.3Å; W270-I274 WeakPolarHBondContact O-CG1 3.49Å; W270-I274 PolarHBondContact O-N 2.88Å; W270-L370 HydrophobicContact CZ3-CD2 4.15Å; W270-L370 HydrophobicContact CZ3-CG 4.42Å; W270-Y374 HydrophobicContact CB-CD2 4.47Å; W270-Y374 HydrophobicContact CB-CE2 4.4Å; W270-Y374 AromaticContact CD1-CD2 3.86Å; W270-Y374 AromaticContact CD1-CE2 3.17Å; W270-Y374 AromaticContact CD1-CZ 3.57Å; W270-Y374 AromaticContact CD2-CD2 3.69Å; W270-Y374 HydrophobicContact CD2-CD2 3.69Å; W270-Y374 AromaticContact CD2-CE2 3.82Å; W270-Y374 HydrophobicContact CD2-CE2 3.82Å; W270-Y374 HydrophobicContact CD2-CG 4.14Å; W270-Y374 AromaticContact CE2-CD1 3.97Å; W270-Y374 AromaticContact CE2-CD2 3.74Å; W270-Y374 AromaticContact CE2-CE1 3.81Å; W270-Y374 AromaticContact CE2-CE2 3.6Å; W270-Y374 AromaticContact CE2-CG 3.93Å; W270-Y374 AromaticContact CE2-CZ 3.63Å; W270-Y374 HydrophobicContact CE3-CD2 4.26Å; W270-Y374 HydrophobicContact CE3-CG 4.43Å; W270-Y374 AromaticContact CG-CD2 3.79Å; W270-Y374 HydrophobicContact CG-CD2 3.79Å; W270-Y374 AromaticContact CG-CE2 3.58Å; W270-Y374 HydrophobicContact CG-CE2 3.58Å; W270-Y374 HydrophobicContact CH2-CD1 4.32Å; W270-Y374 HydrophobicContact CH2-CG 4.34Å; W270-Y374 AromaticContact CZ2-CD1 3.8Å; W270-Y374 HydrophobicContact CZ2-CD1 3.8Å; W270-Y374 HydrophobicContact CZ2-CD2 4.32Å; W270-Y374 AromaticContact CZ2-CE1 3.84Å; W270-Y374 HydrophobicContact CZ2-CE1 3.84Å; W270-Y374 HydrophobicContact CZ2-CE2 4.39Å; W270-Y374 HydrophobicContact CZ2-CG 4.04Å; W270-Y374 AromaticContact NE1-CD2 3.83Å; W270-Y374 AromaticContact NE1-CE1 3.7Å; W270-Y374 AromaticContact NE1-CE2 3.19Å; W270-Y374 AromaticContact NE1-CZ 3.1Å; W270-Y374 PolarHBondContact NE1-OH 3.49Å
271	I	74.2	Confident	73	Confident	16 Å²	16	37.6 Å²	37.6	8%	0.082	19%	0.191	C	C	.	.	H	α-helix	trans	-61.4	-48.8	179.3	-69.1	173.3	0	0	0	110.6	I58 F135 I139 F267 I268 T273 I274 I275	I58-I271 HydrophobicContact CD1-CG2 3.86Å; F135-I271 HydrophobicContact CB-CD1 3.77Å; F135-I271 HydrophobicContact CD1-CD1 4.27Å; F135-I271 HydrophobicContact CG-CD1 4.29Å; I139-I271 HydrophobicContact CD1-CD1 3.9Å; I139-I271 HydrophobicContact CG1-CD1 4.22Å; F267-I271 HydrophobicContact CD1-CD1 3.68Å; F267-I271 HydrophobicContact CE1-CD1 3.39Å; F267-I271 HydrophobicContact CE1-CG1 4.36Å; F267-I271 HydrophobicContact CG-CD1 4.47Å; F267-I271 HydrophobicContact CZ-CD1 3.93Å; F267-I271 PolarHBondContact O-N 3.06Å; I268-I271 PolarHBondContact O-N 3.44Å; I271-T273 VanDerWaalsContact C-N 3.26Å; I271-T273 PolarHBondContact O-N 3.43Å; I271-I274 PolarHBondContact O-N 3Å; I271-I275 HydrophobicContact CG2-CD1 3.56Å; I271-I275 HydrophobicContact CG2-CG1 4.28Å; I271-I275 VanDerWaalsContact O-CG1 3.29Å; I271-I275 WeakPolarHBondContact O-CG1 3.38Å; I271-I275 PolarHBondContact O-N 3.42Å
272	L	79.5	Confident	74	Confident	0 Å²	0	35.9 Å²	35.9	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-58.9	-40.8	177.4	-75.4	174.3	0	0	0	111.4	F55 I58 F59 I268 L276 F377 F381	F55-L272 HydrophobicContact CD2-CD2 3.79Å; F55-L272 HydrophobicContact CE2-CB 4.27Å; F55-L272 HydrophobicContact CE2-CD2 3.77Å; I58-L272 HydrophobicContact CB-CD2 3.86Å; I58-L272 HydrophobicContact CG2-CD1 4.44Å; I58-L272 HydrophobicContact CG2-CD2 3.52Å; I58-L272 HydrophobicContact CG2-CG 3.82Å; F59-L272 HydrophobicContact CB-CD2 4.23Å; F59-L272 HydrophobicContact CD2-CD1 4.45Å; I268-L272 HydrophobicContact CG2-CD1 3.67Å; I268-L272 HydrophobicContact CG2-CG 4.2Å; I268-L272 WeakPolarHBondContact O-CB 3.24Å; I268-L272 WeakPolarHBondContact O-CG 3.43Å; I268-L272 PolarHBondContact O-N 3.13Å; L272-L276 WeakPolarHBondContact O-CB 3.48Å; L272-L276 PolarHBondContact O-N 3.23Å; L272-F377 HydrophobicContact CB-CD1 4.18Å; L272-F377 HydrophobicContact CB-CD2 4.11Å; L272-F377 HydrophobicContact CB-CE1 3.97Å; L272-F377 HydrophobicContact CB-CE2 3.88Å; L272-F377 HydrophobicContact CB-CG 4.26Å; L272-F377 HydrophobicContact CB-CZ 3.82Å; L272-F377 HydrophobicContact CD1-CD1 3.86Å; L272-F377 HydrophobicContact CD1-CE1 3.88Å; L272-F377 HydrophobicContact CG-CE1 4.47Å; L272-F381 HydrophobicContact CD1-CE2 3.83Å; L272-F381 HydrophobicContact CD1-CZ 3.77Å
273	T	81.7	Confident	75	Confident	0 Å²	0	31.3 Å²	31.3	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-60.7	-47.1	176.6	-66.6	0	0	0	0	112.5	S269 W270 I271 S277 L370 Y374 F377	S269-T273 WeakPolarHBondContact O-CB 3.32Å; S269-T273 PolarHBondContact O-N 3.04Å; S269-T273 PolarHBondContact O-OG1 3.12Å; W270-T273 WeakPolarHBondContact O-CB 3.23Å; W270-T273 PolarHBondContact O-N 3.43Å; I271-T273 VanDerWaalsContact C-N 3.26Å; I271-T273 PolarHBondContact O-N 3.43Å; T273-S277 WeakPolarHBondContact O-CB 3.21Å; T273-S277 PolarHBondContact O-N 3.44Å; T273-S277 PolarHBondContact O-OG 3.49Å; T273-L370 HydrophobicContact CG2-CD1 3.47Å; T273-L370 VanDerWaalsContact CG2-CD1 3.47Å; T273-L370 HydrophobicContact CG2-CG 3.69Å; T273-L370 WeakPolarHBondContact CG2-O 3.43Å; T273-Y374 WeakPolarHBondContact OG1-CA 3.44Å; T273-Y374 PolarHBondContact OG1-N 3.35Å; T273-F377 WeakPolarHBondContact OG1-CD2 3.37Å
274	I	79.1	Confident	75.5	Confident	88 Å²	88	30.3 Å²	30.3	45%	0.451	15%	0.151	S	C	.	.	H	α-helix	trans	-67	-44.5	-179.5	-67.5	164.7	0	0	0	110.7	W270 I271 S277 V278	W270-I274 VanDerWaalsContact O-CG1 3.3Å; W270-I274 WeakPolarHBondContact O-CG1 3.49Å; W270-I274 PolarHBondContact O-N 2.88Å; I271-I274 PolarHBondContact O-N 3Å; I274-S277 PolarHBondContact O-N 2.87Å; I274-S277 PolarHBondContact O-OG 2.84Å; I274-V278 WeakPolarHBondContact O-CG2 3.29Å; I274-V278 PolarHBondContact O-N 3.24Å; I274-V278 VanDerWaalsContact O-N 3.11Å
275	I	76.4	Confident	76	Confident	17 Å²	17	32.8 Å²	32.8	9%	0.087	16%	0.164	C	C	.	.	H	α-helix	trans	-65.4	-44.4	179.5	-65.5	173.6	0	0	0	110	I51 I54 F55 I58 I142 I271 V278 L279	I51-I275 HydrophobicContact CG2-CG2 3.73Å; I54-I275 HydrophobicContact CG2-CD1 3.8Å; F55-I275 HydrophobicContact CB-CG2 3.74Å; F55-I275 HydrophobicContact CD2-CG2 4.24Å; F55-I275 HydrophobicContact CG-CG2 4.47Å; I58-I275 HydrophobicContact CD1-CD1 3.61Å; I142-I275 HydrophobicContact CD1-CD1 4.39Å; I271-I275 HydrophobicContact CG2-CD1 3.56Å; I271-I275 HydrophobicContact CG2-CG1 4.28Å; I271-I275 VanDerWaalsContact O-CG1 3.29Å; I271-I275 WeakPolarHBondContact O-CG1 3.38Å; I271-I275 PolarHBondContact O-N 3.42Å; I275-V278 PolarHBondContact O-N 3.39Å; I275-L279 VanDerWaalsContact O-CB 3.3Å; I275-L279 WeakPolarHBondContact O-CB 3.19Å; I275-L279 PolarHBondContact O-N 3.13Å
276	L	82.6	Confident	76.1	Confident	10 Å²	10	34.4 Å²	34.4	5%	0.052	17%	0.173	C	C	.	.	H	α-helix	trans	-62.8	-42.7	177.9	-176.4	62.2	0	0	0	111.6	F55 L272 L279 L280 L332 F377	F55-L276 HydrophobicContact CD2-CB 4.12Å; F55-L276 HydrophobicContact CE2-CB 3.74Å; F55-L276 HydrophobicContact CE2-CD1 4.14Å; F55-L276 HydrophobicContact CE2-CD2 4.39Å; F55-L276 HydrophobicContact CE2-CG 4.3Å; F55-L276 HydrophobicContact CZ-CB 4.46Å; F55-L276 HydrophobicContact CZ-CD1 4.08Å; F55-L276 HydrophobicContact CZ-CD2 4.42Å; L272-L276 WeakPolarHBondContact O-CB 3.48Å; L272-L276 PolarHBondContact O-N 3.23Å; L276-L279 PolarHBondContact O-N 2.88Å; L276-L280 HydrophobicContact CD1-CD1 3.92Å; L276-L280 HydrophobicContact CD1-CD2 4.43Å; L276-L280 HydrophobicContact CD1-CG 3.95Å; L276-L280 HydrophobicContact CD2-CD1 4.33Å; L276-L280 HydrophobicContact CG-CD1 3.72Å; L276-L280 HydrophobicContact CG-CG 4.19Å; L276-L280 WeakPolarHBondContact O-CB 3.27Å; L276-L280 VanDerWaalsContact O-CG 3.22Å; L276-L280 WeakPolarHBondContact O-CG 3.22Å; L276-L280 PolarHBondContact O-N 2.97Å; L276-L332 HydrophobicContact CD2-CD2 4.05Å; L276-F377 HydrophobicContact CD2-CE2 3.94Å; L276-F377 HydrophobicContact CD2-CZ 3.95Å
277	S	81.5	Confident	76.1	Confident	14 Å²	14	33 Å²	33	10%	0.098	17%	0.166	C	C	.	.	H	α-helix	trans	-64	-44	179.7	69.1	0	0	0	0	111.8	T273 I274 L279 L280 F281 L370	T273-S277 WeakPolarHBondContact O-CB 3.21Å; T273-S277 PolarHBondContact O-N 3.44Å; T273-S277 PolarHBondContact O-OG 3.49Å; I274-S277 PolarHBondContact O-N 2.87Å; I274-S277 PolarHBondContact O-OG 2.84Å; S277-L279 VanDerWaalsContact C-N 3.35Å; S277-L279 PolarHBondContact O-N 2.87Å; S277-L280 PolarHBondContact O-N 3.44Å; S277-F281 VanDerWaalsContact O-CB 3.23Å; S277-F281 WeakPolarHBondContact O-CB 3.32Å; S277-F281 PolarHBondContact O-N 2.69Å; S277-L370 WeakPolarHBondContact OG-CD1 3.45Å
278	V	78.3	Confident	76.2	Confident	67 Å²	67	38 Å²	38	41%	0.406	19%	0.191	S	C	.	.	H	α-helix	trans	-62.1	-44	175	173.8	0	0	0	0	110.7	I51 I274 I275 F281 L282	I51-V278 HydrophobicContact CD1-CG1 4.2Å; I274-V278 WeakPolarHBondContact O-CG2 3.29Å; I274-V278 PolarHBondContact O-N 3.24Å; I274-V278 VanDerWaalsContact O-N 3.11Å; I275-V278 PolarHBondContact O-N 3.39Å; V278-F281 PolarHBondContact O-N 2.79Å; V278-L282 HydrophobicContact CG1-CD1 4.13Å; V278-L282 HydrophobicContact CG1-CG 4.49Å; V278-L282 WeakPolarHBondContact O-CG 3.34Å; V278-L282 PolarHBondContact O-N 3.22Å
279	L	78.9	Confident	76.1	Confident	14 Å²	14	45.9 Å²	45.9	7%	0.073	22%	0.22	C	C	.	.	H	α-helix	trans	-61.2	-51.8	178.6	-176.3	131.5	0	0	0	112	L48 I51 L52 I275 L276 S277 F281 L282 V283	L48-L279 HydrophobicContact CD1-CD1 4.43Å; L48-L279 HydrophobicContact CD1-CG 4.06Å; I51-L279 HydrophobicContact CB-CD1 4.31Å; I51-L279 HydrophobicContact CG2-CB 3.9Å; I51-L279 HydrophobicContact CG2-CD1 3.87Å; I51-L279 HydrophobicContact CG2-CG 4.46Å; L52-L279 HydrophobicContact CB-CD1 3.53Å; L52-L279 HydrophobicContact CD1-CD1 3.7Å; L52-L279 HydrophobicContact CD1-CD2 4.25Å; L52-L279 HydrophobicContact CG-CD1 4.2Å; L52-L279 VanDerWaalsContact N-CD1 3.3Å; I275-L279 VanDerWaalsContact O-CB 3.3Å; I275-L279 WeakPolarHBondContact O-CB 3.19Å; I275-L279 PolarHBondContact O-N 3.13Å; L276-L279 PolarHBondContact O-N 2.88Å; S277-L279 VanDerWaalsContact C-N 3.35Å; S277-L279 PolarHBondContact O-N 2.87Å; L279-F281 VanDerWaalsContact C-N 3.26Å; L279-F281 PolarHBondContact O-N 3.25Å; L279-L282 PolarHBondContact O-N 3.36Å; L279-V283 HydrophobicContact CD2-CG2 4.23Å; L279-V283 HydrophobicContact CG-CG2 4.46Å; L279-V283 VanDerWaalsContact O-CG2 3.27Å; L279-V283 WeakPolarHBondContact O-CG2 3.28Å; L279-V283 PolarHBondContact O-N 3.3Å
280	L	82.5	Confident	75.9	Confident	10 Å²	10	47.1 Å²	47.1	5%	0.052	23%	0.227	C	C	.	.	H	α-helix	trans	-61.5	-38.6	179.5	-68.5	171.4	0	0	0	111	L276 S277 V283 G284 I336 L340	L276-L280 HydrophobicContact CD1-CD1 3.92Å; L276-L280 HydrophobicContact CD1-CD2 4.43Å; L276-L280 HydrophobicContact CD1-CG 3.95Å; L276-L280 HydrophobicContact CD2-CD1 4.33Å; L276-L280 HydrophobicContact CG-CD1 3.72Å; L276-L280 HydrophobicContact CG-CG 4.19Å; L276-L280 WeakPolarHBondContact O-CB 3.27Å; L276-L280 VanDerWaalsContact O-CG 3.22Å; L276-L280 WeakPolarHBondContact O-CG 3.22Å; L276-L280 PolarHBondContact O-N 2.97Å; S277-L280 PolarHBondContact O-N 3.44Å; L280-V283 PolarHBondContact O-N 2.8Å; L280-G284 PolarHBondContact O-N 3Å; L280-I336 HydrophobicContact CD1-CG1 4.23Å; L280-I336 HydrophobicContact CD2-CB 4.34Å; L280-I336 HydrophobicContact CD2-CG1 4.35Å; L280-I336 HydrophobicContact CD2-CG2 3.87Å; L280-L340 HydrophobicContact CD2-CD2 4.27Å; L280-L340 HydrophobicContact CD2-CG 4.2Å; L280-L340 WeakPolarHBondContact O-CD2 3.48Å
281	F	78.7	Confident	75.8	Confident	50 Å²	50	44.6 Å²	44.6	22%	0.219	22%	0.22	C	C	.	.	H	α-helix	trans	-61.5	-48.6	176.2	-173.4	-100.6	0	0	0	112.3	S277 V278 L279 G284 I285 A343 L346 Y347	S277-F281 VanDerWaalsContact O-CB 3.23Å; S277-F281 WeakPolarHBondContact O-CB 3.32Å; S277-F281 PolarHBondContact O-N 2.69Å; V278-F281 PolarHBondContact O-N 2.79Å; L279-F281 VanDerWaalsContact C-N 3.26Å; L279-F281 PolarHBondContact O-N 3.25Å; F281-G284 PolarHBondContact O-N 2.86Å; F281-I285 HydrophobicContact CD1-CD1 3.86Å; F281-I285 HydrophobicContact CE1-CD1 3.36Å; F281-I285 HydrophobicContact CE2-CD1 4.26Å; F281-I285 HydrophobicContact CZ-CD1 3.61Å; F281-I285 WeakPolarHBondContact O-CG1 3.25Å; F281-I285 PolarHBondContact O-N 2.87Å; F281-A343 HydrophobicContact CD2-CB 3.66Å; F281-A343 HydrophobicContact CE2-CB 4.19Å; F281-A343 HydrophobicContact CG-CB 4.28Å; F281-L346 HydrophobicContact CE2-CB 4.44Å; F281-L346 HydrophobicContact CE2-CD1 3.77Å; F281-Y347 HydrophobicContact CE2-CD2 4.26Å; F281-Y347 AromaticContact CZ-CD2 3.6Å; F281-Y347 HydrophobicContact CZ-CD2 3.6Å; F281-Y347 AromaticContact CZ-CE2 3.7Å; F281-Y347 HydrophobicContact CZ-CE2 3.7Å
282	L	76.1	Confident	75.6	Confident	32 Å²	32	43.9 Å²	43.9	17%	0.168	22%	0.217	C	C	.	.	H	α-helix	trans	-65.5	-39.7	178.1	-70.4	179.2	0	0	0	112.8	L44 L48 I51 V278 L279 N286	L44-L282 HydrophobicContact CD1-CD1 4.3Å; L44-L282 HydrophobicContact CD1-CD2 3.6Å; L44-L282 HydrophobicContact CD1-CG 4.48Å; L44-L282 HydrophobicContact CG-CD2 4.44Å; L48-L282 HydrophobicContact CD1-CB 3.79Å; L48-L282 HydrophobicContact CD1-CD1 4.47Å; I51-L282 HydrophobicContact CD1-CD1 3.86Å; V278-L282 HydrophobicContact CG1-CD1 4.13Å; V278-L282 HydrophobicContact CG1-CG 4.49Å; V278-L282 WeakPolarHBondContact O-CG 3.34Å; V278-L282 PolarHBondContact O-N 3.22Å; L279-L282 PolarHBondContact O-N 3.36Å; L282-N286 WeakPolarHBondContact O-CB 3.49Å; L282-N286 PolarHBondContact O-N 3.19Å
283	V	77.3	Confident	75.4	Confident	43 Å²	43	46.5 Å²	46.5	26%	0.261	24%	0.235	S	C	.	.	H	α-helix	trans	-61.7	-50.2	173.7	174.6	0	0	0	0	109.8	L48 L279 L280 I285 N286 I287 L340	L48-V283 HydrophobicContact CD1-CG2 3.71Å; L48-V283 HydrophobicContact CD2-CG2 3.93Å; L48-V283 HydrophobicContact CG-CG2 4.32Å; L279-V283 HydrophobicContact CD2-CG2 4.23Å; L279-V283 HydrophobicContact CG-CG2 4.46Å; L279-V283 VanDerWaalsContact O-CG2 3.27Å; L279-V283 WeakPolarHBondContact O-CG2 3.28Å; L279-V283 PolarHBondContact O-N 3.3Å; L280-V283 PolarHBondContact O-N 2.8Å; V283-I285 PolarHBondContact O-N 3.29Å; V283-N286 PolarHBondContact O-N 2.93Å; V283-I287 HydrophobicContact CG1-CD1 3.9Å; V283-I287 HydrophobicContact CG1-CG1 4.21Å; V283-I287 WeakPolarHBondContact O-CG1 3.33Å; V283-I287 PolarHBondContact O-N 3.47Å; V283-I287 VanDerWaalsContact O-N 3.12Å; V283-L340 HydrophobicContact CB-CD2 3.8Å; V283-L340 HydrophobicContact CG1-CD2 3.59Å
284	G	70.2	Confident	75.2	Confident	0 Å²	0	51.1 Å²	51.1	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-58.2	-44.3	-174.7	0	0	0	0	0	113	L280 F281 N286 I287 Q344	L280-G284 PolarHBondContact O-N 3Å; F281-G284 PolarHBondContact O-N 2.86Å; G284-N286 PolarHBondContact O-N 3.07Å; G284-I287 PolarHBondContact O-N 3.22Å; G284-Q344 WeakPolarHBondContact O-CG 3.3Å; G284-Q344 PolarHBondContact O-NE2 3.35Å
285	I	74.2	Confident	75.1	Confident	63 Å²	63	50.4 Å²	50.4	32%	0.323	25%	0.246	S	C	.	.	H	α-helix	trans	-62.8	-31.1	176.5	-65.7	174.5	0	0	0	112.1	F281 V283 A343 Y347	F281-I285 HydrophobicContact CD1-CD1 3.86Å; F281-I285 HydrophobicContact CE1-CD1 3.36Å; F281-I285 HydrophobicContact CE2-CD1 4.26Å; F281-I285 HydrophobicContact CZ-CD1 3.61Å; F281-I285 WeakPolarHBondContact O-CG1 3.25Å; F281-I285 PolarHBondContact O-N 2.87Å; V283-I285 PolarHBondContact O-N 3.29Å; I285-A343 HydrophobicContact CG1-CB 4.37Å; I285-Y347 HydrophobicContact CD1-CD2 4.06Å; I285-Y347 HydrophobicContact CD1-CG 4.2Å
286	N	70.6	Confident	75.2	Confident	51 Å²	51	59.7 Å²	59.7	27%	0.273	28%	0.281	S	S	.	.	H	α-helix	trans	-90.4	-9.5	-174.4	-158.7	31.1	0	0	0	113.7	L282 V283 G284 E288	L282-N286 WeakPolarHBondContact O-CB 3.49Å; L282-N286 PolarHBondContact O-N 3.19Å; V283-N286 PolarHBondContact O-N 2.93Å; G284-N286 PolarHBondContact O-N 3.07Å; N286-E288 PolarHBondContact O-N 3Å
287	I	68.6	Low	75.1	Confident	56 Å²	56	68 Å²	68	29%	0.287	31%	0.311	S	S	.	.			trans	-72.5	118.5	174.8	-69.2	169.3	0	0	0	108.9	V283 G284 R289 L291 L340 Q344	V283-I287 HydrophobicContact CG1-CD1 3.9Å; V283-I287 HydrophobicContact CG1-CG1 4.21Å; V283-I287 WeakPolarHBondContact O-CG1 3.33Å; V283-I287 PolarHBondContact O-N 3.47Å; V283-I287 VanDerWaalsContact O-N 3.12Å; G284-I287 PolarHBondContact O-N 3.22Å; I287-R289 VanDerWaalsContact C-N 3.27Å; I287-R289 HydrophobicContact CG2-CB 4.13Å; I287-R289 WeakPolarHBondContact CG2-O 3.43Å; I287-R289 PolarHBondContact O-N 3.34Å; I287-L291 HydrophobicContact CD1-CD1 3.83Å; I287-L291 HydrophobicContact CG2-CD1 4.4Å; I287-L291 HydrophobicContact CG2-CG 4.31Å; I287-L340 HydrophobicContact CD1-CD2 4.18Å; I287-Q344 PolarHBondContact O-NE2 3.31Å; I287-Q344 VanDerWaalsContact O-NE2 3.17Å
288	E	69	Low	75.2	Confident	173 Å²	173	68.3 Å²	68.3	81%	0.808	31%	0.311	S	S	*	.			trans	-70.7	-22.9	-178.7	-63.3	-174.4	165.7	0	0	113.7	N286	N286-E288 PolarHBondContact O-N 3Å
289	R	68.1	Low	75.4	Confident	165 Å²	165	69.8 Å²	69.8	62%	0.623	31%	0.314	S	S	*	.	S	Bend	trans	-82.7	136.1	179.8	-165.8	174.8	-171.9	160.9	3.8	110.1	I287 L291 Y294 Q344	I287-R289 VanDerWaalsContact C-N 3.27Å; I287-R289 HydrophobicContact CG2-CB 4.13Å; I287-R289 WeakPolarHBondContact CG2-O 3.43Å; I287-R289 PolarHBondContact O-N 3.34Å; R289-L291 PolarHBondContact O-N 3.4Å; R289-Y294 PolarHBondContact NE-OH 3.01Å; R289-Y294 PolarHBondContact NH2-OH 3.35Å; R289-Q344 PolarHBondContact O-NE2 3.24Å
290	D	72.3	Confident	75.7	Confident	27 Å²	27	73.7 Å²	73.7	14%	0.144	34%	0.335	C	S	.	.			trans	-75.7	95.1	178	-162.1	-0.2	0	0	0	110.6	V292 S293 R350 E351	D290-V292 PolarHBondContact O-N 3.36Å; D290-V292 WeakPolarHBondContact OD1-CB 3.45Å; D290-V292 VanDerWaalsContact OD1-CG2 3.28Å; D290-V292 WeakPolarHBondContact OD1-CG2 3.5Å; D290-V292 PolarHBondContact OD1-N 3.04Å; D290-S293 PolarHBondContact O-N 3.44Å; D290-S293 PolarHBondContact O-OG 3.11Å; D290-R350 WeakPolarHBondContact OD2-CB 3.37Å; D290-R350 PolarHBondContact OD2-N 2.89Å; D290-E351 PolarHBondContact OD2-N 3.23Å
291	L	71.2	Confident	75.9	Confident	40 Å²	40	78 Å²	78	21%	0.209	35%	0.351	C	S	.	.	G	3₁₀ helix	trans	-65.9	-22.5	177.5	-60.3	169.2	0	0	0	111.4	I287 R289 S293 Y294 L340 I341	I287-L291 HydrophobicContact CD1-CD1 3.83Å; I287-L291 HydrophobicContact CG2-CD1 4.4Å; I287-L291 HydrophobicContact CG2-CG 4.31Å; R289-L291 PolarHBondContact O-N 3.4Å; L291-S293 PolarHBondContact O-N 3.46Å; L291-Y294 WeakPolarHBondContact O-CB 3.35Å; L291-Y294 PolarHBondContact O-N 3.34Å; L291-L340 HydrophobicContact CD1-CB 3.98Å; L291-I341 HydrophobicContact CB-CG1 3.99Å
292	V	71.8	Confident	76.1	Confident	2 Å²	2	77 Å²	77	1%	0.012	35%	0.347	C	S	.	.	G	3₁₀ helix	trans	-59.7	-32.1	177.7	-176	0	0	0	0	111.3	D290 Y294 F295 Q344 I345 E351 M352	D290-V292 PolarHBondContact O-N 3.36Å; D290-V292 WeakPolarHBondContact OD1-CB 3.45Å; D290-V292 VanDerWaalsContact OD1-CG2 3.28Å; D290-V292 WeakPolarHBondContact OD1-CG2 3.5Å; D290-V292 PolarHBondContact OD1-N 3.04Å; V292-Y294 PolarHBondContact O-N 2.87Å; V292-Y294 VanDerWaalsContact O-N 3.14Å; V292-F295 WeakPolarHBondContact O-CB 3.4Å; V292-F295 PolarHBondContact O-N 2.94Å; V292-Q344 HydrophobicContact CG2-CB 4.17Å; V292-I345 HydrophobicContact CG2-CG1 3.91Å; V292-E351 HydrophobicContact CG1-CB 4.24Å; V292-M352 HydrophobicContact CG1-CB 3.51Å; V292-M352 HydrophobicContact CG1-CE 3.3Å; V292-M352 HydrophobicContact CG1-CG 3.61Å; V292-M352 HydrophobicContact CG1-SD 4.27Å
293	S	74.1	Confident	76.6	Confident	54 Å²	54	78.1 Å²	78.1	38%	0.378	36%	0.362	S	S	.	.	G	3₁₀ helix	trans	-60.9	-23.3	174.6	67	0	0	0	0	113.5	D290 L291 E351	D290-S293 PolarHBondContact O-N 3.44Å; D290-S293 PolarHBondContact O-OG 3.11Å; L291-S293 PolarHBondContact O-N 3.46Å; S293-E351 WeakPolarHBondContact CA-OE2 3.17Å
294	Y	78.3	Confident	77	Confident	97 Å²	97	79 Å²	79	38%	0.38	37%	0.369	S	S	.	.	G	3₁₀ helix	trans	-92.6	5.4	176.9	-60.8	-80.1	0	0	0	113.1	R289 L291 V292 R296 W297 F298	R289-Y294 PolarHBondContact NE-OH 3.01Å; R289-Y294 PolarHBondContact NH2-OH 3.35Å; L291-Y294 WeakPolarHBondContact O-CB 3.35Å; L291-Y294 PolarHBondContact O-N 3.34Å; V292-Y294 PolarHBondContact O-N 2.87Å; V292-Y294 VanDerWaalsContact O-N 3.14Å; Y294-R296 VanDerWaalsContact C-N 3.26Å; Y294-R296 PolarHBondContact O-N 3.45Å; Y294-R296 VanDerWaalsContact O-N 3.14Å; Y294-W297 WeakPolarHBondContact O-CB 3.3Å; Y294-W297 PolarHBondContact O-N 3.09Å; Y294-F298 PolarHBondContact O-N 3.05Å
295	F	76.9	Confident	77.8	Confident	73 Å²	73	79.7 Å²	79.7	32%	0.32	37%	0.373	S	S	.	.	H	α-helix	trans	-54.6	-39.2	-173.7	-173.2	-100.1	0	0	0	113.5	V292 F298 M299 I341 M352	V292-F295 WeakPolarHBondContact O-CB 3.4Å; V292-F295 PolarHBondContact O-N 2.94Å; F295-F298 WeakPolarHBondContact O-CB 3.47Å; F295-F298 PolarHBondContact O-N 3.4Å; F295-M299 HydrophobicContact CD1-CG 4.18Å; F295-M299 HydrophobicContact CE1-CG 3.85Å; F295-M299 HydrophobicContact CE1-SD 4.24Å; F295-M299 HydrophobicContact CZ-CG 4.18Å; F295-M299 HydrophobicContact CZ-SD 3.99Å; F295-M299 WeakPolarHBondContact O-CG 3.44Å; F295-M299 PolarHBondContact O-N 3.01Å; F295-I341 HydrophobicContact CD2-CG2 4.07Å; F295-M352 HydrophobicContact CB-CE 3.48Å; F295-M352 VanDerWaalsContact CB-CE 3.48Å; F295-M352 HydrophobicContact CD1-CE 3.75Å; F295-M352 HydrophobicContact CD2-CE 3.99Å; F295-M352 HydrophobicContact CE1-CE 4.46Å; F295-M352 HydrophobicContact CG-CE 3.47Å; F295-M352 VanDerWaalsContact CG-CE 3.47Å
296	R	77.2	Confident	78.3	Confident	213 Å²	213	80.5 Å²	80.5	80%	0.804	38%	0.377	S	S	*	.	H	α-helix	trans	-63.1	-45.2	176.3	-70.2	-175	179.7	-172.7	1	112.6	Y294 F298 M299 I300	Y294-R296 VanDerWaalsContact C-N 3.26Å; Y294-R296 PolarHBondContact O-N 3.45Å; Y294-R296 VanDerWaalsContact O-N 3.14Å; R296-F298 VanDerWaalsContact C-N 3.26Å; R296-F298 PolarHBondContact O-N 3.35Å; R296-M299 PolarHBondContact O-N 3.15Å; R296-I300 WeakPolarHBondContact O-CG1 3.28Å; R296-I300 PolarHBondContact O-N 3.37Å
297	W	82.3	Confident	79.1	Confident	185 Å²	185	83 Å²	83	70%	0.701	39%	0.39	S	S	*	.	H	α-helix	trans	-64.8	-35.9	175.6	-68.4	108.5	0	0	0	111.3	Y294 I300 Y301	Y294-W297 WeakPolarHBondContact O-CB 3.3Å; Y294-W297 PolarHBondContact O-N 3.09Å; W297-I300 HydrophobicContact CE3-CD1 4.12Å; W297-I300 HydrophobicContact CZ3-CD1 4.39Å; W297-I300 PolarHBondContact O-N 3.14Å; W297-Y301 WeakPolarHBondContact O-CB 3.16Å; W297-Y301 PolarHBondContact O-N 3.25Å
298	F	82.8	Confident	80	Confident	20 Å²	20	83.5 Å²	83.5	9%	0.088	40%	0.395	C	S	.	.	H	α-helix	trans	-63.9	-43.2	175.7	-178.9	-118.8	0	0	0	112.5	Y294 F295 R296 I300 Y301 I302 P337 A338 I341	Y294-F298 PolarHBondContact O-N 3.05Å; F295-F298 WeakPolarHBondContact O-CB 3.47Å; F295-F298 PolarHBondContact O-N 3.4Å; R296-F298 VanDerWaalsContact C-N 3.26Å; R296-F298 PolarHBondContact O-N 3.35Å; F298-I300 VanDerWaalsContact C-N 3.31Å; F298-I300 PolarHBondContact O-N 3.38Å; F298-Y301 HydrophobicContact CD2-CD1 4.02Å; F298-Y301 AromaticContact CE2-CD1 3.9Å; F298-Y301 HydrophobicContact CE2-CD1 3.9Å; F298-Y301 HydrophobicContact CE2-CE1 4.3Å; F298-Y301 WeakPolarHBondContact O-CB 3.35Å; F298-Y301 PolarHBondContact O-N 2.89Å; F298-Y301 VanDerWaalsContact O-N 3.14Å; F298-I302 HydrophobicContact CD1-CD1 3.67Å; F298-I302 HydrophobicContact CD1-CG1 4.38Å; F298-I302 HydrophobicContact CD2-CD1 4.43Å; F298-I302 HydrophobicContact CD2-CG1 4.28Å; F298-I302 HydrophobicContact CE1-CD1 3.11Å; F298-I302 HydrophobicContact CE1-CG1 3.9Å; F298-I302 HydrophobicContact CE2-CD1 3.89Å; F298-I302 HydrophobicContact CE2-CG1 3.68Å; F298-I302 HydrophobicContact CG-CD1 4.3Å; F298-I302 HydrophobicContact CZ-CD1 3.22Å; F298-I302 HydrophobicContact CZ-CG1 3.5Å; F298-I302 VanDerWaalsContact CZ-CG1 3.5Å; F298-I302 WeakPolarHBondContact O-CG1 3.49Å; F298-I302 PolarHBondContact O-N 3.34Å; F298-P337 HydrophobicContact CD2-CB 3.98Å; F298-P337 HydrophobicContact CD2-CG 4.31Å; F298-P337 HydrophobicContact CE2-CB 3.41Å; F298-P337 VanDerWaalsContact CE2-CB 3.41Å; F298-P337 HydrophobicContact CE2-CG 3.4Å; F298-P337 VanDerWaalsContact CE2-CG 3.4Å; F298-P337 HydrophobicContact CZ-CB 4.05Å; F298-P337 HydrophobicContact CZ-CG 4.03Å; F298-A338 HydrophobicContact CE1-CB 3.94Å; F298-A338 VanDerWaalsContact CZ-CA 3.46Å; F298-A338 HydrophobicContact CZ-CB 3.66Å; F298-A338 VanDerWaalsContact CZ-N 3.31Å; F298-I341 HydrophobicContact CB-CD1 3.88Å; F298-I341 HydrophobicContact CD1-CD1 3.37Å; F298-I341 HydrophobicContact CD2-CD1 4.08Å; F298-I341 HydrophobicContact CE1-CD1 3.87Å; F298-I341 HydrophobicContact CG-CD1 3.46Å; F298-I341 VanDerWaalsContact CG-CD1 3.46Å; F298-I341 HydrophobicContact CZ-CD1 4.47Å
299	M	82.5	Confident	80.7	Confident	97 Å²	97	76.5 Å²	76.5	48%	0.478	36%	0.363	S	S	.	.	H	α-helix	trans	-61.7	-38.2	174.8	-69	-58.8	-66.5	0	0	112.4	F295 R296 I302 A303	F295-M299 HydrophobicContact CD1-CG 4.18Å; F295-M299 HydrophobicContact CE1-CG 3.85Å; F295-M299 HydrophobicContact CE1-SD 4.24Å; F295-M299 HydrophobicContact CZ-CG 4.18Å; F295-M299 HydrophobicContact CZ-SD 3.99Å; F295-M299 WeakPolarHBondContact O-CG 3.44Å; F295-M299 PolarHBondContact O-N 3.01Å; R296-M299 PolarHBondContact O-N 3.15Å; M299-I302 HydrophobicContact SD-CD1 4.21Å; M299-A303 WeakPolarHBondContact O-CB 3.45Å; M299-A303 PolarHBondContact O-N 3.24Å
300	I	85.9	Confident	81.5	Confident	97 Å²	97	73.3 Å²	73.3	50%	0.497	36%	0.358	S	S	.	.	H	α-helix	trans	-64.1	-43.1	173.9	-64.4	167.2	0	0	0	110.5	R296 W297 F298 A303 S304	R296-I300 WeakPolarHBondContact O-CG1 3.28Å; R296-I300 PolarHBondContact O-N 3.37Å; W297-I300 HydrophobicContact CE3-CD1 4.12Å; W297-I300 HydrophobicContact CZ3-CD1 4.39Å; W297-I300 PolarHBondContact O-N 3.14Å; F298-I300 VanDerWaalsContact C-N 3.31Å; F298-I300 PolarHBondContact O-N 3.38Å; I300-A303 PolarHBondContact O-N 3.18Å; I300-S304 WeakPolarHBondContact O-CB 3.35Å; I300-S304 PolarHBondContact O-N 3.31Å; I300-S304 PolarHBondContact O-OG 2.77Å
301	Y	85.9	Confident	82.2	Confident	101 Å²	101	76.7 Å²	76.7	40%	0.396	38%	0.375	S	S	.	.	H	α-helix	trans	-62.2	-47.1	176.6	168.4	-95.9	0	0	0	112.2	W297 F298 A303 S304 I305 A333 P337	W297-Y301 WeakPolarHBondContact O-CB 3.16Å; W297-Y301 PolarHBondContact O-N 3.25Å; F298-Y301 HydrophobicContact CD2-CD1 4.02Å; F298-Y301 AromaticContact CE2-CD1 3.9Å; F298-Y301 HydrophobicContact CE2-CD1 3.9Å; F298-Y301 HydrophobicContact CE2-CE1 4.3Å; F298-Y301 WeakPolarHBondContact O-CB 3.35Å; F298-Y301 PolarHBondContact O-N 2.89Å; F298-Y301 VanDerWaalsContact O-N 3.14Å; Y301-A303 PolarHBondContact O-N 3.42Å; Y301-S304 WeakPolarHBondContact O-CB 3.36Å; Y301-S304 PolarHBondContact O-N 2.83Å; Y301-I305 HydrophobicContact CD1-CD1 4.2Å; Y301-I305 HydrophobicContact CD2-CD1 4.36Å; Y301-I305 HydrophobicContact CE1-CD1 3.48Å; Y301-I305 VanDerWaalsContact CE1-CD1 3.48Å; Y301-I305 HydrophobicContact CE2-CD1 3.68Å; Y301-I305 HydrophobicContact CE2-CG1 4.35Å; Y301-I305 PolarHBondContact O-N 2.76Å; Y301-I305 VanDerWaalsContact OH-CD1 3.27Å; Y301-I305 WeakPolarHBondContact OH-CD1 3.42Å; Y301-A333 WeakPolarHBondContact CE1-O 3.32Å; Y301-A333 PolarHBondContact OH-O 2.97Å; Y301-P337 HydrophobicContact CE1-CG 3.96Å
302	I	83.7	Confident	82.8	Confident	27 Å²	27	76.7 Å²	76.7	14%	0.138	38%	0.375	C	S	.	.	H	α-helix	trans	-59	-48.7	175.4	-64.9	167.5	0	0	0	110.4	F298 M299 S304 I305 I306 I334	F298-I302 HydrophobicContact CD1-CD1 3.67Å; F298-I302 HydrophobicContact CD1-CG1 4.38Å; F298-I302 HydrophobicContact CD2-CD1 4.43Å; F298-I302 HydrophobicContact CD2-CG1 4.28Å; F298-I302 HydrophobicContact CE1-CD1 3.11Å; F298-I302 HydrophobicContact CE1-CG1 3.9Å; F298-I302 HydrophobicContact CE2-CD1 3.89Å; F298-I302 HydrophobicContact CE2-CG1 3.68Å; F298-I302 HydrophobicContact CG-CD1 4.3Å; F298-I302 HydrophobicContact CZ-CD1 3.22Å; F298-I302 HydrophobicContact CZ-CG1 3.5Å; F298-I302 VanDerWaalsContact CZ-CG1 3.5Å; F298-I302 WeakPolarHBondContact O-CG1 3.49Å; F298-I302 PolarHBondContact O-N 3.34Å; M299-I302 HydrophobicContact SD-CD1 4.21Å; I302-S304 PolarHBondContact O-N 3.05Å; I302-I305 PolarHBondContact O-N 2.99Å; I302-I305 VanDerWaalsContact O-N 3.16Å; I302-I306 HydrophobicContact CG2-CD1 3.56Å; I302-I306 HydrophobicContact CG2-CG1 4.1Å; I302-I306 WeakPolarHBondContact O-CG1 3.34Å; I302-I306 PolarHBondContact O-N 3.3Å; I302-I334 HydrophobicContact CG1-CG2 4.23Å; I302-I334 HydrophobicContact CG2-CG2 4.16Å
303	A	86.2	Confident	83.2	Confident	57 Å²	57	80 Å²	80	47%	0.471	39%	0.392	S	S	.	.	H	α-helix	trans	-58.1	-38.1	178.9	0	0	0	0	0	111.8	M299 I300 Y301 L307	M299-A303 WeakPolarHBondContact O-CB 3.45Å; M299-A303 PolarHBondContact O-N 3.24Å; I300-A303 PolarHBondContact O-N 3.18Å; Y301-A303 PolarHBondContact O-N 3.42Å; A303-L307 WeakPolarHBondContact O-CB 3.4Å; A303-L307 PolarHBondContact O-N 2.9Å
304	S	86	Confident	83.5	Confident	60 Å²	60	82.8 Å²	82.8	42%	0.42	40%	0.402	S	S	.	.	H	α-helix	trans	-65.8	-44.1	176.7	-56	0	0	0	0	112	I300 Y301 I302 L307 V308	I300-S304 WeakPolarHBondContact O-CB 3.35Å; I300-S304 PolarHBondContact O-N 3.31Å; I300-S304 PolarHBondContact O-OG 2.77Å; Y301-S304 WeakPolarHBondContact O-CB 3.36Å; Y301-S304 PolarHBondContact O-N 2.83Å; I302-S304 PolarHBondContact O-N 3.05Å; S304-L307 WeakPolarHBondContact O-CB 3.35Å; S304-L307 PolarHBondContact O-N 2.82Å; S304-V308 WeakPolarHBondContact O-CG2 3.39Å; S304-V308 PolarHBondContact O-N 2.93Å
305	I	85.3	Confident	83.5	Confident	16 Å²	16	80 Å²	80	8%	0.082	40%	0.396	C	S	.	.	H	α-helix	trans	-68.2	-41.4	176.8	-64	179.5	0	0	0	111.2	Y301 I302 L307 V308 I309 L330 A333 I334	Y301-I305 HydrophobicContact CD1-CD1 4.2Å; Y301-I305 HydrophobicContact CD2-CD1 4.36Å; Y301-I305 HydrophobicContact CE1-CD1 3.48Å; Y301-I305 VanDerWaalsContact CE1-CD1 3.48Å; Y301-I305 HydrophobicContact CE2-CD1 3.68Å; Y301-I305 HydrophobicContact CE2-CG1 4.35Å; Y301-I305 PolarHBondContact O-N 2.76Å; Y301-I305 VanDerWaalsContact OH-CD1 3.27Å; Y301-I305 WeakPolarHBondContact OH-CD1 3.42Å; I302-I305 PolarHBondContact O-N 2.99Å; I302-I305 VanDerWaalsContact O-N 3.16Å; I305-L307 PolarHBondContact O-N 3.27Å; I305-V308 CarbonylContact O-C 3.59Å; I305-V308 WeakPolarHBondContact O-CA 3.15Å; I305-V308 WeakPolarHBondContact O-CB 3.44Å; I305-V308 PolarHBondContact O-N 2.99Å; I305-I309 HydrophobicContact CG2-CD1 3.93Å; I305-I309 HydrophobicContact CG2-CG1 4.22Å; I305-I309 WeakPolarHBondContact O-CG1 3.33Å; I305-I309 PolarHBondContact O-N 2.85Å; I305-L330 HydrophobicContact CG2-CB 4.12Å; I305-L330 HydrophobicContact CG2-CD2 4.17Å; I305-A333 HydrophobicContact CD1-CB 4.13Å; I305-I334 HydrophobicContact CB-CD1 3.97Å; I305-I334 HydrophobicContact CB-CG1 3.88Å; I305-I334 HydrophobicContact CD1-CG1 4.03Å; I305-I334 HydrophobicContact CG2-CD1 3.57Å; I305-I334 HydrophobicContact CG2-CG1 3.7Å
306	I	86	Confident	83.4	Confident	79 Å²	79	81.2 Å²	81.2	41%	0.405	40%	0.398	S	S	.	.	H	α-helix	trans	-58.1	-42.2	175.4	-69.3	173.6	0	0	0	110	I302 V308 I309 L310 I334	I302-I306 HydrophobicContact CG2-CD1 3.56Å; I302-I306 HydrophobicContact CG2-CG1 4.1Å; I302-I306 WeakPolarHBondContact O-CG1 3.34Å; I302-I306 PolarHBondContact O-N 3.3Å; I306-V308 VanDerWaalsContact C-N 3.34Å; I306-V308 PolarHBondContact O-N 2.95Å; I306-I309 PolarHBondContact O-N 3.43Å; I306-L310 HydrophobicContact CG2-CD1 4.07Å; I306-L310 HydrophobicContact CG2-CG 4.36Å; I306-L310 WeakPolarHBondContact O-CB 3.33Å; I306-L310 VanDerWaalsContact O-CG 3.27Å; I306-L310 WeakPolarHBondContact O-CG 3.39Å; I306-L310 PolarHBondContact O-N 3.49Å; I306-I334 HydrophobicContact CG1-CD1 4.09Å
307	L	87.2	Confident	83.4	Confident	104 Å²	104	75.4 Å²	75.4	55%	0.545	39%	0.39	S	S	.	.	H	α-helix	trans	-59.9	-43.1	174.2	-177.1	66.8	0	0	0	112	A303 S304 I305 L310 I311	A303-L307 WeakPolarHBondContact O-CB 3.4Å; A303-L307 PolarHBondContact O-N 2.9Å; S304-L307 WeakPolarHBondContact O-CB 3.35Å; S304-L307 PolarHBondContact O-N 2.82Å; I305-L307 PolarHBondContact O-N 3.27Å; L307-L310 PolarHBondContact O-N 2.92Å; L307-I311 HydrophobicContact CG-CD1 4.22Å; L307-I311 VanDerWaalsContact O-CG1 3.3Å; L307-I311 WeakPolarHBondContact O-CG1 3.45Å; L307-I311 PolarHBondContact O-N 3.18Å
308	V	87.1	Confident	83.3	Confident	66 Å²	66	72.4 Å²	72.4	40%	0.4	39%	0.387	S	S	.	.	H	α-helix	trans	-62.5	-45	175.2	173.9	0	0	0	0	111.3	S304 I305 I306 L310 I311 L312 L330	S304-V308 WeakPolarHBondContact O-CG2 3.39Å; S304-V308 PolarHBondContact O-N 2.93Å; I305-V308 CarbonylContact O-C 3.59Å; I305-V308 WeakPolarHBondContact O-CA 3.15Å; I305-V308 WeakPolarHBondContact O-CB 3.44Å; I305-V308 PolarHBondContact O-N 2.99Å; I306-V308 VanDerWaalsContact C-N 3.34Å; I306-V308 PolarHBondContact O-N 2.95Å; V308-L310 VanDerWaalsContact C-N 3.33Å; V308-L310 PolarHBondContact O-N 3.05Å; V308-I311 PolarHBondContact O-N 3.13Å; V308-L312 HydrophobicContact CG1-CD1 4.03Å; V308-L312 HydrophobicContact CG1-CG 4.39Å; V308-L312 WeakPolarHBondContact O-CB 3.45Å; V308-L312 WeakPolarHBondContact O-CG 3.43Å; V308-L312 PolarHBondContact O-N 3.21Å; V308-L330 HydrophobicContact CG1-CD1 4.1Å
309	I	83.6	Confident	82.8	Confident	26 Å²	26	77 Å²	77	13%	0.133	41%	0.412	C	S	.	.	H	α-helix	trans	-59.3	-45.7	176.2	-67.7	170.8	0	0	0	110	I305 I306 I311 L312 L313 L330 V331 I334	I305-I309 HydrophobicContact CG2-CD1 3.93Å; I305-I309 HydrophobicContact CG2-CG1 4.22Å; I305-I309 WeakPolarHBondContact O-CG1 3.33Å; I305-I309 PolarHBondContact O-N 2.85Å; I306-I309 PolarHBondContact O-N 3.43Å; I309-I311 VanDerWaalsContact C-N 3.33Å; I309-I311 PolarHBondContact O-N 3.24Å; I309-L312 CarbonylContact O-C 3.54Å; I309-L312 WeakPolarHBondContact O-CA 3.28Å; I309-L312 WeakPolarHBondContact O-CB 2.95Å; I309-L312 PolarHBondContact O-N 3.46Å; I309-L312 VanDerWaalsContact O-N 3.08Å; I309-L313 WeakPolarHBondContact O-CG 3.45Å; I309-L313 PolarHBondContact O-N 3.47Å; I309-L330 HydrophobicContact CD1-CB 4.15Å; I309-L330 HydrophobicContact CG1-CB 4.05Å; I309-L330 HydrophobicContact CG1-CD1 4.15Å; I309-V331 HydrophobicContact CD1-CG2 4.29Å; I309-I334 HydrophobicContact CD1-CD1 4.02Å
310	L	85.5	Confident	82.2	Confident	99 Å²	99	75.5 Å²	75.5	52%	0.518	41%	0.408	S	S	.	.	H	α-helix	trans	-59.2	-41.9	177.2	-73.4	170.6	0	0	0	112.3	I306 L307 V308 L312 L313	I306-L310 HydrophobicContact CG2-CD1 4.07Å; I306-L310 HydrophobicContact CG2-CG 4.36Å; I306-L310 WeakPolarHBondContact O-CB 3.33Å; I306-L310 VanDerWaalsContact O-CG 3.27Å; I306-L310 WeakPolarHBondContact O-CG 3.39Å; I306-L310 PolarHBondContact O-N 3.49Å; L307-L310 PolarHBondContact O-N 2.92Å; V308-L310 VanDerWaalsContact C-N 3.33Å; V308-L310 PolarHBondContact O-N 3.05Å; L310-L312 VanDerWaalsContact C-N 3.34Å; L310-L313 HydrophobicContact CD2-CD1 4.01Å; L310-L313 WeakPolarHBondContact O-CB 3.25Å; L310-L313 PolarHBondContact O-N 3.27Å
311	I	86.4	Confident	81.4	Confident	98 Å²	98	75.2 Å²	75.2	50%	0.503	41%	0.411	S	S	.	.	H	α-helix	trans	-64.2	-41.3	174.6	-66.9	163.9	0	0	0	110.5	L307 V308 I309 L313 I314 P315	L307-I311 HydrophobicContact CG-CD1 4.22Å; L307-I311 VanDerWaalsContact O-CG1 3.3Å; L307-I311 WeakPolarHBondContact O-CG1 3.45Å; L307-I311 PolarHBondContact O-N 3.18Å; V308-I311 PolarHBondContact O-N 3.13Å; I309-I311 VanDerWaalsContact C-N 3.33Å; I309-I311 PolarHBondContact O-N 3.24Å; I311-L313 VanDerWaalsContact C-N 3.26Å; I311-L313 PolarHBondContact O-N 3.46Å; I311-I314 WeakPolarHBondContact O-CB 3.31Å; I311-I314 PolarHBondContact O-N 3.42Å; I311-P315 WeakPolarHBondContact O-CD 3.32Å
312	L	83.8	Confident	80.6	Confident	40 Å²	40	73.5 Å²	73.5	21%	0.209	42%	0.418	C	S	.	.	H	α-helix	trans	-67.3	-21.6	177.9	-72.9	175.1	0	0	0	113.4	V308 I309 L310 I314 P315 W316 V323 L330	V308-L312 HydrophobicContact CG1-CD1 4.03Å; V308-L312 HydrophobicContact CG1-CG 4.39Å; V308-L312 WeakPolarHBondContact O-CB 3.45Å; V308-L312 WeakPolarHBondContact O-CG 3.43Å; V308-L312 PolarHBondContact O-N 3.21Å; I309-L312 CarbonylContact O-C 3.54Å; I309-L312 WeakPolarHBondContact O-CA 3.28Å; I309-L312 WeakPolarHBondContact O-CB 2.95Å; I309-L312 PolarHBondContact O-N 3.46Å; I309-L312 VanDerWaalsContact O-N 3.08Å; L310-L312 VanDerWaalsContact C-N 3.34Å; L312-I314 PolarHBondContact O-N 3.37Å; L312-P315 HydrophobicContact CD2-CG 4.37Å; L312-P315 WeakPolarHBondContact O-CD 3.32Å; L312-P315 VanDerWaalsContact O-CG 3.26Å; L312-P315 WeakPolarHBondContact O-CG 3.42Å; L312-W316 WeakPolarHBondContact O-CB 3.5Å; L312-W316 PolarHBondContact O-N 2.94Å; L312-V323 HydrophobicContact CB-CG1 3.94Å; L312-V323 HydrophobicContact CD2-CG1 4.37Å; L312-V323 WeakPolarHBondContact O-CG1 3.46Å; L312-L330 HydrophobicContact CD1-CD1 3.38Å
313	L	79.7	Confident	80	Confident	70 Å²	70	72.7 Å²	72.7	37%	0.366	41%	0.414	S	S	.	.	H	α-helix	trans	-61	-27.9	172.6	-64.5	176.9	0	0	0	112.3	I309 L310 I311 W316 S317	I309-L313 WeakPolarHBondContact O-CG 3.45Å; I309-L313 PolarHBondContact O-N 3.47Å; L310-L313 HydrophobicContact CD2-CD1 4.01Å; L310-L313 WeakPolarHBondContact O-CB 3.25Å; L310-L313 PolarHBondContact O-N 3.27Å; I311-L313 VanDerWaalsContact C-N 3.26Å; I311-L313 PolarHBondContact O-N 3.46Å; L313-W316 HydrophobicContact CD2-CE3 3.5Å; L313-W316 HydrophobicContact CD2-CZ3 3.84Å; L313-W316 PolarHBondContact O-N 3.3Å; L313-S317 PolarHBondContact O-N 2.95Å
314	I	80.5	Confident	79.2	Confident	113 Å²	113	70.1 Å²	70.1	58%	0.579	39%	0.392	S	S	*	.	H	α-helix	trans	-63.1	-59.6	177.1	-56.9	170.5	0	0	0	111	I311 L312 W316 S317	I311-I314 WeakPolarHBondContact O-CB 3.31Å; I311-I314 PolarHBondContact O-N 3.42Å; L312-I314 PolarHBondContact O-N 3.37Å; I314-W316 PolarHBondContact O-N 2.84Å; I314-S317 WeakPolarHBondContact O-CB 3.42Å; I314-S317 PolarHBondContact O-N 2.92Å; I314-S317 PolarHBondContact O-OG 3.3Å
315	P	78.4	Confident	78.4	Confident	39 Å²	39	72 Å²	72	25%	0.253	39%	0.391	S	S	.	.	H	α-helix	trans	-66.5	-25.2	176	27	-35.3	0	0	0	112.8	I311 L312 S317 I318 V320 V323	I311-P315 WeakPolarHBondContact O-CD 3.32Å; L312-P315 HydrophobicContact CD2-CG 4.37Å; L312-P315 WeakPolarHBondContact O-CD 3.32Å; L312-P315 VanDerWaalsContact O-CG 3.26Å; L312-P315 WeakPolarHBondContact O-CG 3.42Å; P315-S317 VanDerWaalsContact C-N 3.33Å; P315-I318 PolarHBondContact O-N 3.11Å; P315-I318 VanDerWaalsContact O-N 3.17Å; P315-V320 HydrophobicContact CB-CB 4.49Å; P315-V320 HydrophobicContact CB-CG2 4.24Å; P315-V320 WeakPolarHBondContact O-CG2 3.49Å; P315-V320 PolarHBondContact O-N 3.5Å; P315-V323 HydrophobicContact CB-CG2 3.86Å; P315-V323 HydrophobicContact CG-CG2 3.83Å
316	W	75.5	Confident	78.1	Confident	98 Å²	98	73.1 Å²	73.1	37%	0.371	40%	0.402	S	S	.	.	H	α-helix	trans	-64	-38.6	172.5	-163.6	38.5	0	0	0	112.3	L312 L313 I314 I318 N319 V323 T324 I327	L312-W316 WeakPolarHBondContact O-CB 3.5Å; L312-W316 PolarHBondContact O-N 2.94Å; L313-W316 HydrophobicContact CD2-CE3 3.5Å; L313-W316 HydrophobicContact CD2-CZ3 3.84Å; L313-W316 PolarHBondContact O-N 3.3Å; I314-W316 PolarHBondContact O-N 2.84Å; W316-I318 PolarHBondContact O-N 3.37Å; W316-N319 PolarHBondContact O-N 3.15Å; W316-V323 HydrophobicContact CB-CB 4.36Å; W316-V323 HydrophobicContact CB-CG1 3.76Å; W316-V323 HydrophobicContact CG-CG1 4.24Å; W316-T324 PolarHBondContact NE1-OG1 3.38Å; W316-I327 HydrophobicContact CD2-CD1 4.07Å; W316-I327 HydrophobicContact CE3-CD1 4.23Å; W316-I327 HydrophobicContact CG-CD1 4.28Å
317	S	76.9	Confident	77.8	Confident	91 Å²	91	70 Å²	70	64%	0.636	39%	0.386	S	S	*	.	H	α-helix	trans	-61.8	-21.3	174.8	78.5	0	0	0	0	113.4	L313 I314 P315 N319	L313-S317 PolarHBondContact O-N 2.95Å; I314-S317 WeakPolarHBondContact O-CB 3.42Å; I314-S317 PolarHBondContact O-N 2.92Å; I314-S317 PolarHBondContact O-OG 3.3Å; P315-S317 VanDerWaalsContact C-N 3.33Å; S317-N319 VanDerWaalsContact C-N 3.31Å
318	I	79.7	Confident	77.4	Confident	123 Å²	123	65 Å²	65	63%	0.631	36%	0.36	S	S	*	.	T	Hydrogen-bonded Turn	trans	-95.4	15.1	177.4	-47	169.1	0	0	0	110.7	P315 W316 V320	P315-I318 PolarHBondContact O-N 3.11Å; P315-I318 VanDerWaalsContact O-N 3.17Å; W316-I318 PolarHBondContact O-N 3.37Å; I318-V320 VanDerWaalsContact C-N 3.29Å; I318-V320 PolarHBondContact O-N 3.42Å
319	N	72.4	Confident	77.1	Confident	116 Å²	116	64.8 Å²	64.8	62%	0.62	36%	0.36	S	S	*	.	T	Hydrogen-bonded Turn	trans	60.5	27.2	178.1	-76.8	-49.1	0	0	0	115.5	W316 S317 T321	W316-N319 PolarHBondContact O-N 3.15Å; S317-N319 VanDerWaalsContact C-N 3.31Å; N319-T321 PolarHBondContact O-N 3.12Å; N319-T321 VanDerWaalsContact O-N 3.07Å
320	V	71.4	Confident	77.2	Confident	65 Å²	65	65.5 Å²	65.5	39%	0.394	36%	0.363	S	S	.	.			trans	-68.4	108.4	172.7	-177.7	0	0	0	0	109.4	P315 I318 A322 V323	P315-V320 HydrophobicContact CB-CB 4.49Å; P315-V320 HydrophobicContact CB-CG2 4.24Å; P315-V320 WeakPolarHBondContact O-CG2 3.49Å; P315-V320 PolarHBondContact O-N 3.5Å; I318-V320 VanDerWaalsContact C-N 3.29Å; I318-V320 PolarHBondContact O-N 3.42Å; V320-A322 VanDerWaalsContact C-N 3.3Å; V320-A322 HydrophobicContact CG1-CB 4.28Å; V320-A322 PolarHBondContact O-N 3.33Å; V320-V323 HydrophobicContact CB-CG2 3.84Å; V320-V323 HydrophobicContact CG1-CG2 3.87Å; V320-V323 WeakPolarHBondContact O-CB 3.34Å; V320-V323 PolarHBondContact O-N 3.06Å; V320-V323 VanDerWaalsContact O-N 3.13Å
321	T	67.7	Low	77.1	Confident	91 Å²	91	61.1 Å²	61.1	56%	0.558	34%	0.341	S	S	*	.	H	α-helix	trans	-60	-37.4	-174.9	48.7	0	0	0	0	113	N319 V323 T324	N319-T321 PolarHBondContact O-N 3.12Å; N319-T321 VanDerWaalsContact O-N 3.07Å; T321-V323 PolarHBondContact O-N 2.84Å; T321-V323 VanDerWaalsContact O-N 3.13Å; T321-T324 WeakPolarHBondContact O-CB 3.38Å; T321-T324 PolarHBondContact O-N 3.08Å; T321-T324 VanDerWaalsContact O-N 3.12Å
322	A	70.5	Confident	76.9	Confident	65 Å²	65	57.3 Å²	57.3	54%	0.537	32%	0.322	S	S	.	.	H	α-helix	trans	-57.9	-26.9	178.3	0	0	0	0	0	113.3	V320 W325 A326	V320-A322 VanDerWaalsContact C-N 3.3Å; V320-A322 HydrophobicContact CG1-CB 4.28Å; V320-A322 PolarHBondContact O-N 3.33Å; A322-W325 PolarHBondContact O-N 3.02Å; A322-A326 PolarHBondContact O-N 3.34Å; A322-A326 VanDerWaalsContact O-N 3.17Å
323	V	70.4	Confident	76.9	Confident	10 Å²	10	56.9 Å²	56.9	6%	0.061	32%	0.324	C	S	.	.	H	α-helix	trans	-70.5	-38.4	179.5	-179.8	0	0	0	0	111.4	L312 P315 W316 V320 T321 W325 A326 I327	L312-V323 HydrophobicContact CB-CG1 3.94Å; L312-V323 HydrophobicContact CD2-CG1 4.37Å; L312-V323 WeakPolarHBondContact O-CG1 3.46Å; P315-V323 HydrophobicContact CB-CG2 3.86Å; P315-V323 HydrophobicContact CG-CG2 3.83Å; W316-V323 HydrophobicContact CB-CB 4.36Å; W316-V323 HydrophobicContact CB-CG1 3.76Å; W316-V323 HydrophobicContact CG-CG1 4.24Å; V320-V323 HydrophobicContact CB-CG2 3.84Å; V320-V323 HydrophobicContact CG1-CG2 3.87Å; V320-V323 WeakPolarHBondContact O-CB 3.34Å; V320-V323 PolarHBondContact O-N 3.06Å; V320-V323 VanDerWaalsContact O-N 3.13Å; T321-V323 PolarHBondContact O-N 2.84Å; T321-V323 VanDerWaalsContact O-N 3.13Å; V323-W325 VanDerWaalsContact C-N 3.27Å; V323-W325 PolarHBondContact O-N 3.32Å; V323-A326 PolarHBondContact O-N 2.98Å; V323-I327 HydrophobicContact CG1-CD1 3.84Å; V323-I327 HydrophobicContact CG1-CG1 4.2Å; V323-I327 VanDerWaalsContact O-CG1 3.32Å; V323-I327 WeakPolarHBondContact O-CG1 3.38Å; V323-I327 PolarHBondContact O-N 3.48Å
324	T	69.1	Low	77.2	Confident	3 Å²	3	54 Å²	54	2%	0.018	31%	0.309	C	S	.	.	H	α-helix	trans	-57.4	-44.8	175.3	-48.2	0	0	0	0	110.5	W316 T321 A326 I327 V379 L382	W316-T324 PolarHBondContact NE1-OG1 3.38Å; T321-T324 WeakPolarHBondContact O-CB 3.38Å; T321-T324 PolarHBondContact O-N 3.08Å; T321-T324 VanDerWaalsContact O-N 3.12Å; T324-A326 VanDerWaalsContact C-N 3.29Å; T324-A326 PolarHBondContact O-N 3.05Å; T324-I327 PolarHBondContact O-N 2.94Å; T324-V379 HydrophobicContact CG2-CG1 4.17Å; T324-V379 WeakPolarHBondContact CG2-O 2.95Å; T324-V379 WeakPolarHBondContact O-CG1 3.1Å; T324-L382 HydrophobicContact CG2-CB 4.18Å
325	W	69.6	Low	77.4	Confident	101 Å²	101	48.8 Å²	48.8	38%	0.383	28%	0.282	S	S	.	.	H	α-helix	trans	-66.3	-26.9	177.1	-69.8	95.4	0	0	0	113.8	A66 A322 V323 P329 I384	A66-W325 HydrophobicContact CB-CH2 4.24Å; A322-W325 PolarHBondContact O-N 3.02Å; V323-W325 VanDerWaalsContact C-N 3.27Å; V323-W325 PolarHBondContact O-N 3.32Å; W325-P329 WeakPolarHBondContact O-CD 3.19Å; W325-P329 VanDerWaalsContact O-CG 3.28Å; W325-P329 WeakPolarHBondContact O-CG 3.14Å; W325-I384 HydrophobicContact CH2-CD1 3.98Å; W325-I384 HydrophobicContact CH2-CG1 3.64Å; W325-I384 HydrophobicContact CZ2-CG1 3.79Å
326	A	78	Confident	77.6	Confident	39 Å²	39	50.2 Å²	50.2	32%	0.322	29%	0.287	S	S	.	.	H	α-helix	trans	-82.6	-33.1	178.4	0	0	0	0	0	112.8	A322 V323 T324 P329 L330	A322-A326 PolarHBondContact O-N 3.34Å; A322-A326 VanDerWaalsContact O-N 3.17Å; V323-A326 PolarHBondContact O-N 2.98Å; T324-A326 VanDerWaalsContact C-N 3.29Å; T324-A326 PolarHBondContact O-N 3.05Å; A326-P329 WeakPolarHBondContact O-CD 3.15Å; A326-L330 WeakPolarHBondContact O-CD1 3.24Å; A326-L330 VanDerWaalsContact O-CG 3.23Å; A326-L330 WeakPolarHBondContact O-CG 3.14Å; A326-L330 PolarHBondContact O-N 3.03Å
327	I	80.4	Confident	78	Confident	13 Å²	13	47 Å²	47	7%	0.067	28%	0.279	C	S	.	.	H	α-helix	trans	-65.1	-43.4	-178	-68.4	164.7	0	0	0	111.1	W316 V323 T324 L330 V331 V379	W316-I327 HydrophobicContact CD2-CD1 4.07Å; W316-I327 HydrophobicContact CE3-CD1 4.23Å; W316-I327 HydrophobicContact CG-CD1 4.28Å; V323-I327 HydrophobicContact CG1-CD1 3.84Å; V323-I327 HydrophobicContact CG1-CG1 4.2Å; V323-I327 VanDerWaalsContact O-CG1 3.32Å; V323-I327 WeakPolarHBondContact O-CG1 3.38Å; V323-I327 PolarHBondContact O-N 3.48Å; T324-I327 PolarHBondContact O-N 2.94Å; I327-L330 PolarHBondContact O-N 3.18Å; I327-V331 HydrophobicContact CG2-CG2 4.15Å; I327-V331 WeakPolarHBondContact O-CG2 3.41Å; I327-V331 PolarHBondContact O-N 3.37Å; I327-V379 HydrophobicContact CB-CG1 3.81Å; I327-V379 HydrophobicContact CG2-CG1 3.81Å
328	G	78.5	Confident	78.4	Confident	0 Å²	0	43.3 Å²	43.3	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-55.3	-55.3	-179.8	0	0	0	0	0	113.6	L330 V331 L332 G376	G328-L330 VanDerWaalsContact C-N 3.32Å; G328-L330 PolarHBondContact O-N 3.23Å; G328-V331 WeakPolarHBondContact O-CB 3.4Å; G328-V331 PolarHBondContact O-N 3.23Å; G328-L332 PolarHBondContact O-N 3.13Å; G328-G376 VanDerWaalsContact CA-O 3.3Å; G328-G376 WeakPolarHBondContact CA-O 3.44Å
329	P	81.6	Confident	78.6	Confident	60 Å²	60	37.8 Å²	37.8	39%	0.39	23%	0.225	S	C	.	.	H	α-helix	trans	-58.1	-38	173.7	-25.5	33.7	0	0	0	113.9	W325 A326 V331 L332 A333 M380	W325-P329 WeakPolarHBondContact O-CD 3.19Å; W325-P329 VanDerWaalsContact O-CG 3.28Å; W325-P329 WeakPolarHBondContact O-CG 3.14Å; A326-P329 WeakPolarHBondContact O-CD 3.15Å; P329-V331 VanDerWaalsContact C-N 3.35Å; P329-L332 PolarHBondContact O-N 2.88Å; P329-A333 WeakPolarHBondContact O-CB 3.5Å; P329-A333 PolarHBondContact O-N 3.29Å; P329-M380 HydrophobicContact CG-CE 3.87Å
330	L	84.3	Confident	79.1	Confident	41 Å²	41	33.5 Å²	33.5	22%	0.215	20%	0.202	C	C	.	.	H	α-helix	trans	-65.3	-38.6	176.8	-72.2	170.4	0	0	0	112	I305 V308 I309 L312 A326 I327 G328 A333 I334	I305-L330 HydrophobicContact CG2-CB 4.12Å; I305-L330 HydrophobicContact CG2-CD2 4.17Å; V308-L330 HydrophobicContact CG1-CD1 4.1Å; I309-L330 HydrophobicContact CD1-CB 4.15Å; I309-L330 HydrophobicContact CG1-CB 4.05Å; I309-L330 HydrophobicContact CG1-CD1 4.15Å; L312-L330 HydrophobicContact CD1-CD1 3.38Å; A326-L330 WeakPolarHBondContact O-CD1 3.24Å; A326-L330 VanDerWaalsContact O-CG 3.23Å; A326-L330 WeakPolarHBondContact O-CG 3.14Å; A326-L330 PolarHBondContact O-N 3.03Å; I327-L330 PolarHBondContact O-N 3.18Å; G328-L330 VanDerWaalsContact C-N 3.32Å; G328-L330 PolarHBondContact O-N 3.23Å; L330-A333 WeakPolarHBondContact O-CB 3.47Å; L330-A333 PolarHBondContact O-N 3.28Å; L330-I334 PolarHBondContact O-N 3.31Å
331	V	83.5	Confident	79.6	Confident	8 Å²	8	30.9 Å²	30.9	5%	0.048	19%	0.186	C	C	.	.	H	α-helix	trans	-62.6	-47.6	173.1	170.2	0	0	0	0	110.2	I309 I327 G328 P329 A333 I334 I335 F372	I309-V331 HydrophobicContact CD1-CG2 4.29Å; I327-V331 HydrophobicContact CG2-CG2 4.15Å; I327-V331 WeakPolarHBondContact O-CG2 3.41Å; I327-V331 PolarHBondContact O-N 3.37Å; G328-V331 WeakPolarHBondContact O-CB 3.4Å; G328-V331 PolarHBondContact O-N 3.23Å; P329-V331 VanDerWaalsContact C-N 3.35Å; V331-A333 VanDerWaalsContact C-N 3.27Å; V331-A333 PolarHBondContact O-N 2.83Å; V331-I334 WeakPolarHBondContact O-CB 3.28Å; V331-I334 PolarHBondContact O-N 3.2Å; V331-I334 VanDerWaalsContact O-N 3.11Å; V331-I335 HydrophobicContact CG1-CD1 3.57Å; V331-I335 WeakPolarHBondContact O-CD1 3.4Å; V331-I335 VanDerWaalsContact O-CG1 3.29Å; V331-I335 WeakPolarHBondContact O-CG1 3.32Å; V331-I335 PolarHBondContact O-N 3.18Å; V331-I335 VanDerWaalsContact O-N 3.17Å; V331-F372 HydrophobicContact CG1-CD1 3.77Å; V331-F372 HydrophobicContact CG1-CE1 3.8Å; V331-F372 HydrophobicContact CG1-CG 4.27Å; V331-F372 HydrophobicContact CG1-CZ 4.34Å; V331-F372 WeakPolarHBondContact CG1-O 3.37Å; V331-F372 HydrophobicContact CG2-CE1 4.48Å; V331-F372 HydrophobicContact CG2-CZ 4.46Å
332	L	83.5	Confident	80.2	Confident	18 Å²	18	26.8 Å²	26.8	9%	0.094	16%	0.161	C	C	.	.	H	α-helix	trans	-61.7	-34.7	175.4	-66.2	178.5	0	0	0	112.6	L276 G328 P329 I334 I335 I336 F377 M380	L276-L332 HydrophobicContact CD2-CD2 4.05Å; G328-L332 PolarHBondContact O-N 3.13Å; P329-L332 PolarHBondContact O-N 2.88Å; L332-I334 PolarHBondContact O-N 3.39Å; L332-I335 PolarHBondContact O-N 3.4Å; L332-I335 VanDerWaalsContact O-N 3.12Å; L332-I336 VanDerWaalsContact O-CG1 3.3Å; L332-I336 WeakPolarHBondContact O-CG1 3.47Å; L332-I336 PolarHBondContact O-N 3.49Å; L332-F377 HydrophobicContact CD1-CD1 4.44Å; L332-F377 HydrophobicContact CD1-CE1 3.93Å; L332-F377 HydrophobicContact CD1-CZ 4.06Å; L332-F377 HydrophobicContact CD2-CD2 4.29Å; L332-F377 HydrophobicContact CD2-CE2 3.87Å; L332-F377 HydrophobicContact CD2-CZ 4Å; L332-M380 HydrophobicContact CD1-CE 3.57Å
333	A	83.4	Confident	80.6	Confident	31 Å²	31	23.7 Å²	23.7	26%	0.256	14%	0.135	S	C	.	.	H	α-helix	trans	-66.5	-22.2	176.8	0	0	0	0	0	113.6	Y301 I305 P329 L330 V331 P337	Y301-A333 WeakPolarHBondContact CE1-O 3.32Å; Y301-A333 PolarHBondContact OH-O 2.97Å; I305-A333 HydrophobicContact CD1-CB 4.13Å; P329-A333 WeakPolarHBondContact O-CB 3.5Å; P329-A333 PolarHBondContact O-N 3.29Å; L330-A333 WeakPolarHBondContact O-CB 3.47Å; L330-A333 PolarHBondContact O-N 3.28Å; V331-A333 VanDerWaalsContact C-N 3.27Å; V331-A333 PolarHBondContact O-N 2.83Å; A333-P337 VanDerWaalsContact O-CD 3.23Å; A333-P337 WeakPolarHBondContact O-CD 3.36Å; A333-P337 VanDerWaalsContact O-CG 3.27Å; A333-P337 WeakPolarHBondContact O-CG 3.46Å
334	I	85.2	Confident	80.9	Confident	10 Å²	10	23.5 Å²	23.5	5%	0.051	13%	0.134	C	C	.	.	H	α-helix	trans	-79.2	-43.3	168.9	-70	166.9	0	0	0	110.4	I302 I305 I306 I309 L330 V331 L332 P337 A338 F372	I302-I334 HydrophobicContact CG1-CG2 4.23Å; I302-I334 HydrophobicContact CG2-CG2 4.16Å; I305-I334 HydrophobicContact CB-CD1 3.97Å; I305-I334 HydrophobicContact CB-CG1 3.88Å; I305-I334 HydrophobicContact CD1-CG1 4.03Å; I305-I334 HydrophobicContact CG2-CD1 3.57Å; I305-I334 HydrophobicContact CG2-CG1 3.7Å; I306-I334 HydrophobicContact CG1-CD1 4.09Å; I309-I334 HydrophobicContact CD1-CD1 4.02Å; L330-I334 PolarHBondContact O-N 3.31Å; V331-I334 WeakPolarHBondContact O-CB 3.28Å; V331-I334 PolarHBondContact O-N 3.2Å; V331-I334 VanDerWaalsContact O-N 3.11Å; L332-I334 PolarHBondContact O-N 3.39Å; I334-P337 WeakPolarHBondContact O-CD 3.5Å; I334-P337 WeakPolarHBondContact O-CG 3.44Å; I334-A338 WeakPolarHBondContact O-CB 3.32Å; I334-A338 PolarHBondContact O-N 3.39Å; I334-F372 HydrophobicContact CD1-CE1 4.36Å; I334-F372 HydrophobicContact CG2-CE1 4.34Å
335	I	85.4	Confident	81.2	Confident	2 Å²	2	24.3 Å²	24.3	1%	0.01	14%	0.138	C	C	.	.	H	α-helix	trans	-74.9	-44.4	-168.2	-65.5	160.6	0	0	0	112.2	V331 L332 A338 S339 F372	V331-I335 HydrophobicContact CG1-CD1 3.57Å; V331-I335 WeakPolarHBondContact O-CD1 3.4Å; V331-I335 VanDerWaalsContact O-CG1 3.29Å; V331-I335 WeakPolarHBondContact O-CG1 3.32Å; V331-I335 PolarHBondContact O-N 3.18Å; V331-I335 VanDerWaalsContact O-N 3.17Å; L332-I335 PolarHBondContact O-N 3.4Å; L332-I335 VanDerWaalsContact O-N 3.12Å; I335-A338 WeakPolarHBondContact O-CB 3.38Å; I335-A338 PolarHBondContact O-N 2.91Å; I335-S339 WeakPolarHBondContact O-CB 3.3Å; I335-S339 PolarHBondContact O-N 3.46Å; I335-S339 PolarHBondContact O-OG 3.12Å; I335-F372 HydrophobicContact CD1-CB 3.96Å; I335-F372 HydrophobicContact CD1-CD1 3.7Å; I335-F372 HydrophobicContact CD1-CG 4.2Å; I335-F372 WeakPolarHBondContact CD1-O 3.44Å; I335-F372 HydrophobicContact CG1-CB 4.28Å; I335-F372 HydrophobicContact CG1-CD1 3.68Å; I335-F372 HydrophobicContact CG1-CG 4.45Å
336	I	82.6	Confident	81.4	Confident	70 Å²	70	21.8 Å²	21.8	36%	0.359	13%	0.131	S	C	.	.	H	α-helix	trans	-49.5	-57.6	-179.4	-71	166.3	0	0	0	111.1	L280 L332 A338 L340	L280-I336 HydrophobicContact CD1-CG1 4.23Å; L280-I336 HydrophobicContact CD2-CB 4.34Å; L280-I336 HydrophobicContact CD2-CG1 4.35Å; L280-I336 HydrophobicContact CD2-CG2 3.87Å; L332-I336 VanDerWaalsContact O-CG1 3.3Å; L332-I336 WeakPolarHBondContact O-CG1 3.47Å; L332-I336 PolarHBondContact O-N 3.49Å; I336-A338 PolarHBondContact O-N 3.45Å; I336-L340 HydrophobicContact CG2-CD1 4.32Å; I336-L340 VanDerWaalsContact O-CG 3.27Å; I336-L340 WeakPolarHBondContact O-CG 3.43Å; I336-L340 PolarHBondContact O-N 3.43Å
337	P	83.4	Confident	80.9	Confident	31 Å²	31	27.9 Å²	27.9	20%	0.201	15%	0.147	C	C	.	.	H	α-helix	trans	-67.1	-34	177.1	25.4	-34.8	0	0	0	113.5	F298 Y301 A333 I334 L340 I341	F298-P337 HydrophobicContact CD2-CB 3.98Å; F298-P337 HydrophobicContact CD2-CG 4.31Å; F298-P337 HydrophobicContact CE2-CB 3.41Å; F298-P337 VanDerWaalsContact CE2-CB 3.41Å; F298-P337 HydrophobicContact CE2-CG 3.4Å; F298-P337 VanDerWaalsContact CE2-CG 3.4Å; F298-P337 HydrophobicContact CZ-CB 4.05Å; F298-P337 HydrophobicContact CZ-CG 4.03Å; Y301-P337 HydrophobicContact CE1-CG 3.96Å; A333-P337 VanDerWaalsContact O-CD 3.23Å; A333-P337 WeakPolarHBondContact O-CD 3.36Å; A333-P337 VanDerWaalsContact O-CG 3.27Å; A333-P337 WeakPolarHBondContact O-CG 3.46Å; I334-P337 WeakPolarHBondContact O-CD 3.5Å; I334-P337 WeakPolarHBondContact O-CG 3.44Å; P337-L340 PolarHBondContact O-N 3.46Å; P337-I341 WeakPolarHBondContact O-CG1 3.41Å; P337-I341 PolarHBondContact O-N 2.83Å; P337-I341 VanDerWaalsContact O-N 3.11Å
338	A	84.7	Confident	79.9	Confident	13 Å²	13	29.5 Å²	29.5	11%	0.107	17%	0.167	C	C	.	.	H	α-helix	trans	-62.4	-47.7	177.7	0	0	0	0	0	112.2	F298 I334 I335 I336 L340 I341 E342 L369	F298-A338 HydrophobicContact CE1-CB 3.94Å; F298-A338 VanDerWaalsContact CZ-CA 3.46Å; F298-A338 HydrophobicContact CZ-CB 3.66Å; F298-A338 VanDerWaalsContact CZ-N 3.31Å; I334-A338 WeakPolarHBondContact O-CB 3.32Å; I334-A338 PolarHBondContact O-N 3.39Å; I335-A338 WeakPolarHBondContact O-CB 3.38Å; I335-A338 PolarHBondContact O-N 2.91Å; I336-A338 PolarHBondContact O-N 3.45Å; A338-L340 VanDerWaalsContact C-N 3.34Å; A338-L340 PolarHBondContact O-N 2.94Å; A338-I341 PolarHBondContact O-N 3.22Å; A338-E342 WeakPolarHBondContact O-CB 3.4Å; A338-E342 PolarHBondContact O-N 3.26Å; A338-L369 HydrophobicContact CB-CD1 4.17Å; A338-L369 HydrophobicContact CB-CD2 3.52Å
339	S	84.2	Confident	78.9	Confident	6 Å²	6	30.2 Å²	30.2	4%	0.042	18%	0.175	C	C	.	.	H	α-helix	trans	-66.4	-34.7	179.5	-62.4	0	0	0	0	112.3	I335 E342 A343	I335-S339 WeakPolarHBondContact O-CB 3.3Å; I335-S339 PolarHBondContact O-N 3.46Å; I335-S339 PolarHBondContact O-OG 3.12Å; S339-E342 PolarHBondContact O-N 2.99Å; S339-A343 VanDerWaalsContact O-CB 3.31Å; S339-A343 WeakPolarHBondContact O-CB 3.22Å; S339-A343 PolarHBondContact O-N 2.82Å
340	L	83.8	Confident	78	Confident	26 Å²	26	37.2 Å²	37.2	14%	0.136	19%	0.194	C	C	.	.	H	α-helix	trans	-64	-44.4	174.2	-71.1	171	0	0	0	111.8	L280 V283 I287 L291 I336 P337 A338 Q344	L280-L340 HydrophobicContact CD2-CD2 4.27Å; L280-L340 HydrophobicContact CD2-CG 4.2Å; L280-L340 WeakPolarHBondContact O-CD2 3.48Å; V283-L340 HydrophobicContact CB-CD2 3.8Å; V283-L340 HydrophobicContact CG1-CD2 3.59Å; I287-L340 HydrophobicContact CD1-CD2 4.18Å; L291-L340 HydrophobicContact CD1-CB 3.98Å; I336-L340 HydrophobicContact CG2-CD1 4.32Å; I336-L340 VanDerWaalsContact O-CG 3.27Å; I336-L340 WeakPolarHBondContact O-CG 3.43Å; I336-L340 PolarHBondContact O-N 3.43Å; P337-L340 PolarHBondContact O-N 3.46Å; A338-L340 VanDerWaalsContact C-N 3.34Å; A338-L340 PolarHBondContact O-N 2.94Å; L340-Q344 PolarHBondContact O-N 3.43Å
341	I	82.3	Confident	77.1	Confident	11 Å²	11	41.4 Å²	41.4	6%	0.056	21%	0.212	C	C	.	.	H	α-helix	trans	-66.5	-44.9	176.8	-69.3	166.7	0	0	0	110.4	L291 F295 F298 P337 A338 A343 Q344 I345	L291-I341 HydrophobicContact CB-CG1 3.99Å; F295-I341 HydrophobicContact CD2-CG2 4.07Å; F298-I341 HydrophobicContact CB-CD1 3.88Å; F298-I341 HydrophobicContact CD1-CD1 3.37Å; F298-I341 HydrophobicContact CD2-CD1 4.08Å; F298-I341 HydrophobicContact CE1-CD1 3.87Å; F298-I341 HydrophobicContact CG-CD1 3.46Å; F298-I341 VanDerWaalsContact CG-CD1 3.46Å; F298-I341 HydrophobicContact CZ-CD1 4.47Å; P337-I341 WeakPolarHBondContact O-CG1 3.41Å; P337-I341 PolarHBondContact O-N 2.83Å; P337-I341 VanDerWaalsContact O-N 3.11Å; A338-I341 PolarHBondContact O-N 3.22Å; I341-A343 VanDerWaalsContact C-N 3.32Å; I341-A343 PolarHBondContact O-N 3.48Å; I341-Q344 PolarHBondContact O-N 3.4Å; I341-Q344 VanDerWaalsContact O-N 3.13Å; I341-I345 HydrophobicContact CG2-CD1 3.76Å; I341-I345 HydrophobicContact CG2-CG1 4.28Å; I341-I345 WeakPolarHBondContact O-CG1 3.49Å; I341-I345 PolarHBondContact O-N 3.01Å
342	E	80.5	Confident	76.2	Confident	5 Å²	5	44.5 Å²	44.5	2%	0.023	23%	0.227	C	C	.	.	H	α-helix	trans	-55.7	-47.1	176.6	-179.1	-171.3	-142.5	0	0	111.7	A338 S339 Q344 I345 L346 V365 H366 L369	A338-E342 WeakPolarHBondContact O-CB 3.4Å; A338-E342 PolarHBondContact O-N 3.26Å; S339-E342 PolarHBondContact O-N 2.99Å; E342-Q344 PolarHBondContact O-N 3.1Å; E342-I345 PolarHBondContact O-N 2.96Å; E342-I345 VanDerWaalsContact O-N 3.12Å; E342-L346 HydrophobicContact CG-CD1 4.07Å; E342-L346 PolarHBondContact O-N 3.41Å; E342-V365 HydrophobicContact CG-CG1 4.38Å; E342-V365 VanDerWaalsContact OE1-C 3.29Å; E342-V365 WeakPolarHBondContact OE1-CG1 3.38Å; E342-H366 WeakPolarHBondContact OE1-CA 3.25Å; E342-H366 VanDerWaalsContact OE1-CB 3.24Å; E342-H366 WeakPolarHBondContact OE1-CB 3.36Å; E342-H366 IonicContact OE1-CG 3.77Å; E342-H366 PolarHBondContact OE1-N 3.1Å; E342-H366 IonicContact OE1-ND1 2.93Å; E342-H366 IonicContact OE2-CE1 3.98Å; E342-H366 IonicContact OE2-CG 3.23Å; E342-H366 IonicContact OE2-ND1 3.05Å; E342-H366 PolarHBondContact OE2-ND1 2.91Å; E342-L369 HydrophobicContact CB-CD1 4.15Å; E342-L369 WeakPolarHBondContact OE2-CD1 3.49Å
343	A	77.3	Confident	75.6	Confident	0 Å²	0	51.1 Å²	51.1	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-59.6	-37.1	178.7	0	0	0	0	0	112.3	F281 I285 S339 I341 Y347	F281-A343 HydrophobicContact CD2-CB 3.66Å; F281-A343 HydrophobicContact CE2-CB 4.19Å; F281-A343 HydrophobicContact CG-CB 4.28Å; I285-A343 HydrophobicContact CG1-CB 4.37Å; S339-A343 VanDerWaalsContact O-CB 3.31Å; S339-A343 WeakPolarHBondContact O-CB 3.22Å; S339-A343 PolarHBondContact O-N 2.82Å; I341-A343 VanDerWaalsContact C-N 3.32Å; I341-A343 PolarHBondContact O-N 3.48Å; A343-Y347 PolarHBondContact O-N 3.34Å
344	Q	76.5	Confident	74.8	Confident	6 Å²	6	51.9 Å²	51.9	3%	0.028	25%	0.248	C	C	.	.	H	α-helix	trans	-68.7	-45.9	172.3	-71.8	-166.9	-22.3	0	0	112	G284 I287 R289 V292 L340 I341 E342 L346 Y347 G348 G349	G284-Q344 WeakPolarHBondContact O-CG 3.3Å; G284-Q344 PolarHBondContact O-NE2 3.35Å; I287-Q344 PolarHBondContact O-NE2 3.31Å; I287-Q344 VanDerWaalsContact O-NE2 3.17Å; R289-Q344 PolarHBondContact O-NE2 3.24Å; V292-Q344 HydrophobicContact CG2-CB 4.17Å; L340-Q344 PolarHBondContact O-N 3.43Å; I341-Q344 PolarHBondContact O-N 3.4Å; I341-Q344 VanDerWaalsContact O-N 3.13Å; E342-Q344 PolarHBondContact O-N 3.1Å; Q344-L346 PolarHBondContact O-N 3.31Å; Q344-Y347 PolarHBondContact O-N 3Å; Q344-G348 CarbonylContact O-C 3.38Å; Q344-G348 WeakPolarHBondContact O-CA 3.46Å; Q344-G348 PolarHBondContact O-N 3.4Å; Q344-G349 WeakPolarHBondContact O-CA 3.06Å; Q344-G349 PolarHBondContact O-N 2.85Å
345	I	77.3	Confident	74	Confident	20 Å²	20	59.2 Å²	59.2	10%	0.103	28%	0.275	C	S	.	.	H	α-helix	trans	-58.7	-34	177.9	-62.6	168.7	0	0	0	111.4	V292 I341 E342 Y353 Y354	V292-I345 HydrophobicContact CG2-CG1 3.91Å; I341-I345 HydrophobicContact CG2-CD1 3.76Å; I341-I345 HydrophobicContact CG2-CG1 4.28Å; I341-I345 WeakPolarHBondContact O-CG1 3.49Å; I341-I345 PolarHBondContact O-N 3.01Å; E342-I345 PolarHBondContact O-N 2.96Å; E342-I345 VanDerWaalsContact O-N 3.12Å; I345-Y353 WeakPolarHBondContact O-CA 3.33Å; I345-Y354 HydrophobicContact CB-CD2 4.34Å; I345-Y354 HydrophobicContact CB-CE2 4.14Å; I345-Y354 HydrophobicContact CG2-CD1 4.41Å; I345-Y354 HydrophobicContact CG2-CD2 3.53Å; I345-Y354 HydrophobicContact CG2-CE1 4.37Å; I345-Y354 HydrophobicContact CG2-CE2 3.55Å; I345-Y354 HydrophobicContact CG2-CG 4.01Å; I345-Y354 PolarHBondContact O-N 3.36Å
346	L	72.9	Confident	73	Confident	48 Å²	48	70.9 Å²	70.9	25%	0.251	32%	0.319	S	S	.	.	H	α-helix	trans	-71.4	-42.5	177.8	-84.2	165.4	0	0	0	114.2	F281 E342 Q344 Y354 A362	F281-L346 HydrophobicContact CE2-CB 4.44Å; F281-L346 HydrophobicContact CE2-CD1 3.77Å; E342-L346 HydrophobicContact CG-CD1 4.07Å; E342-L346 PolarHBondContact O-N 3.41Å; Q344-L346 PolarHBondContact O-N 3.31Å; L346-Y354 HydrophobicContact CD2-CD2 3.68Å; L346-Y354 HydrophobicContact CD2-CE2 4.15Å; L346-Y354 HydrophobicContact CG-CD2 3.78Å; L346-Y354 HydrophobicContact CG-CE2 3.91Å; L346-A362 HydrophobicContact CD2-CB 3.7Å
347	Y	66.9	Low	72.5	Confident	166 Å²	166	75.5 Å²	75.5	65%	0.651	34%	0.339	S	S	*	.	H	α-helix	trans	-136.3	-0.3	-167.1	-78.3	-78.9	0	0	0	116.6	F281 I285 A343 Q344	F281-Y347 HydrophobicContact CE2-CD2 4.26Å; F281-Y347 AromaticContact CZ-CD2 3.6Å; F281-Y347 HydrophobicContact CZ-CD2 3.6Å; F281-Y347 AromaticContact CZ-CE2 3.7Å; F281-Y347 HydrophobicContact CZ-CE2 3.7Å; I285-Y347 HydrophobicContact CD1-CD2 4.06Å; I285-Y347 HydrophobicContact CD1-CG 4.2Å; A343-Y347 PolarHBondContact O-N 3.34Å; Q344-Y347 PolarHBondContact O-N 3Å
348	G	59.4	Low	72.2	Confident	47 Å²	47	77 Å²	77	49%	0.485	35%	0.345	S	S	.	.	T	Hydrogen-bonded Turn	trans	-154	0.7	-172.8	0	0	0	0	0	117.7	Q344	Q344-G348 CarbonylContact O-C 3.38Å; Q344-G348 WeakPolarHBondContact O-CA 3.46Å; Q344-G348 PolarHBondContact O-N 3.4Å
349	G	59.2	Low	71.5	Confident	16 Å²	16	82.7 Å²	82.7	17%	0.165	37%	0.368	C	S	.	.			trans	-72.2	133.9	-175.6	0	0	0	0	0	111.7	Q344	Q344-G349 WeakPolarHBondContact O-CA 3.06Å; Q344-G349 PolarHBondContact O-N 2.85Å
350	R	62.6	Low	70.9	Confident	207 Å²	207	88.4 Å²	88.4	78%	0.781	40%	0.397	S	S	*	.	S	Bend	trans	-92.9	-35.1	175.2	-57.9	-178.4	-178	-178.3	2.5	111.6	D290	D290-R350 WeakPolarHBondContact OD2-CB 3.37Å; D290-R350 PolarHBondContact OD2-N 2.89Å
351	E	64.7	Low	70.5	Confident	128 Å²	128	93 Å²	93	60%	0.598	42%	0.416	S	S	*	.	S	Bend	trans	-91.5	-43.5	-178.8	-69.5	-170.8	167	0	0	113.9	D290 V292 S293	D290-E351 PolarHBondContact OD2-N 3.23Å; V292-E351 HydrophobicContact CG1-CB 4.24Å; S293-E351 WeakPolarHBondContact CA-OE2 3.17Å
352	M	64	Low	70.2	Confident	74 Å²	74	92.6 Å²	92.6	37%	0.365	41%	0.414	S	S	.	.			trans	-128.1	130.1	178.1	-54.8	-168.7	-87.1	0	0	109.7	V292 F295	V292-M352 HydrophobicContact CG1-CB 3.51Å; V292-M352 HydrophobicContact CG1-CE 3.3Å; V292-M352 HydrophobicContact CG1-CG 3.61Å; V292-M352 HydrophobicContact CG1-SD 4.27Å; F295-M352 HydrophobicContact CB-CE 3.48Å; F295-M352 VanDerWaalsContact CB-CE 3.48Å; F295-M352 HydrophobicContact CD1-CE 3.75Å; F295-M352 HydrophobicContact CD2-CE 3.99Å; F295-M352 HydrophobicContact CE1-CE 4.46Å; F295-M352 HydrophobicContact CG-CE 3.47Å; F295-M352 VanDerWaalsContact CG-CE 3.47Å
353	Y	71.3	Confident	69.8	Low	157 Å²	157	94.9 Å²	94.9	62%	0.616	43%	0.43	S	S	*	.			trans	-142.5	148.4	177.4	60.2	-87.2	0	0	0	109.4	I345	I345-Y353 WeakPolarHBondContact O-CA 3.33Å
354	Y	67.5	Low	69.9	Low	47 Å²	47	99.8 Å²	99.8	18%	0.184	46%	0.456	C	S	.	.			trans	-69.6	133.2	171	-71.8	-62.3	0	0	0	109.9	I345 L346 D358 F361 A362	I345-Y354 HydrophobicContact CB-CD2 4.34Å; I345-Y354 HydrophobicContact CB-CE2 4.14Å; I345-Y354 HydrophobicContact CG2-CD1 4.41Å; I345-Y354 HydrophobicContact CG2-CD2 3.53Å; I345-Y354 HydrophobicContact CG2-CE1 4.37Å; I345-Y354 HydrophobicContact CG2-CE2 3.55Å; I345-Y354 HydrophobicContact CG2-CG 4.01Å; I345-Y354 PolarHBondContact O-N 3.36Å; L346-Y354 HydrophobicContact CD2-CD2 3.68Å; L346-Y354 HydrophobicContact CD2-CE2 4.15Å; L346-Y354 HydrophobicContact CG-CD2 3.78Å; L346-Y354 HydrophobicContact CG-CE2 3.91Å; Y354-D358 HydrophobicContact CD1-CB 3.97Å; Y354-F361 HydrophobicContact CD1-CD1 4.29Å; Y354-F361 AromaticContact CE1-CD1 3.56Å; Y354-F361 HydrophobicContact CE1-CD1 3.56Å; Y354-F361 AromaticContact CE1-CE1 3.85Å; Y354-F361 HydrophobicContact CE1-CE1 3.85Å; Y354-A362 HydrophobicContact CD1-CB 3.97Å; Y354-A362 HydrophobicContact CD2-CB 3.45Å; Y354-A362 VanDerWaalsContact CD2-CB 3.45Å; Y354-A362 HydrophobicContact CE1-CB 4Å; Y354-A362 HydrophobicContact CE2-CB 3.43Å; Y354-A362 VanDerWaalsContact CE2-CB 3.43Å; Y354-A362 HydrophobicContact CG-CB 3.71Å
355	R	67	Low	70.1	Confident	163 Å²	163	101.5 Å²	101.5	62%	0.615	47%	0.467	S	S	*	.			trans	-69.4	156.9	166.1	-60.2	-179.4	176.8	-175.6	0.6	107.9	E357 D358	R355-E357 PolarHBondContact O-N 3.23Å; R355-E357 VanDerWaalsContact O-N 3.08Å; R355-D358 VanDerWaalsContact CB-OD2 3.3Å; R355-D358 WeakPolarHBondContact CB-OD2 3.32Å; R355-D358 PolarHBondContact N-OD2 2.91Å; R355-D358 VanDerWaalsContact N-OD2 3.07Å; R355-D358 WeakPolarHBondContact O-CB 3.28Å; R355-D358 PolarHBondContact O-N 2.77Å
356	R	64.3	Low	70.2	Confident	248 Å²	248	103.2 Å²	103.2	94%	0.936	47%	0.474	S	S	*	.	G	3₁₀ helix	trans	-54.5	-31.1	176.4	-70	-176.9	-180	177.9	-0	112.5	D358	R356-D358 VanDerWaalsContact C-N 3.3Å
357	E	73.8	Confident	70.5	Confident	167 Å²	167	105.5 Å²	105.5	78%	0.78	49%	0.486	S	S	*	.	G	3₁₀ helix	trans	-69.9	-25.6	177.4	-64.6	169	-167.1	0	0	112.7	R355 F359	R355-E357 PolarHBondContact O-N 3.23Å; R355-E357 VanDerWaalsContact O-N 3.08Å; E357-F359 VanDerWaalsContact C-N 3.26Å; E357-F359 PolarHBondContact O-N 2.97Å
358	D	75.5	Confident	71.3	Confident	61 Å²	61	103.9 Å²	103.9	33%	0.326	48%	0.483	S	S	.	.	G	3₁₀ helix	trans	-87.3	10.4	-177.2	-54.8	-40.3	0	0	0	112.7	Y354 R355 R356 I360 F361 A362	Y354-D358 HydrophobicContact CD1-CB 3.97Å; R355-D358 VanDerWaalsContact CB-OD2 3.3Å; R355-D358 WeakPolarHBondContact CB-OD2 3.32Å; R355-D358 PolarHBondContact N-OD2 2.91Å; R355-D358 VanDerWaalsContact N-OD2 3.07Å; R355-D358 WeakPolarHBondContact O-CB 3.28Å; R355-D358 PolarHBondContact O-N 2.77Å; R356-D358 VanDerWaalsContact C-N 3.3Å; D358-I360 PolarHBondContact O-N 3.17Å; D358-F361 WeakPolarHBondContact O-CA 3.21Å; D358-F361 WeakPolarHBondContact O-CB 3.35Å; D358-F361 PolarHBondContact O-N 2.98Å; D358-A362 PolarHBondContact O-N 3.48Å
359	F	70.1	Confident	72.5	Confident	133 Å²	133	102.3 Å²	102.3	58%	0.583	46%	0.463	S	S	*	.	H	α-helix	trans	-57.1	-37.5	-177.5	-178.5	-98.1	0	0	0	112.8	E357 A362 S363	E357-F359 VanDerWaalsContact C-N 3.26Å; E357-F359 PolarHBondContact O-N 2.97Å; F359-A362 PolarHBondContact O-N 2.86Å; F359-S363 WeakPolarHBondContact O-CB 3.39Å; F359-S363 PolarHBondContact O-N 3.32Å; F359-S363 PolarHBondContact O-OG 3.13Å
360	I	72.1	Confident	73.5	Confident	127 Å²	127	102.9 Å²	102.9	65%	0.651	46%	0.463	S	S	*	.	H	α-helix	trans	-63.7	-45.7	175.8	-62.9	174.9	0	0	0	110	D358 S363 L364	D358-I360 PolarHBondContact O-N 3.17Å; I360-S363 PolarHBondContact O-N 3.4Å; I360-L364 HydrophobicContact CG2-CD1 4.26Å; I360-L364 WeakPolarHBondContact O-CG 3.27Å; I360-L364 PolarHBondContact O-N 2.98Å
361	F	76.3	Confident	74.4	Confident	123 Å²	123	96.4 Å²	96.4	54%	0.539	45%	0.446	S	S	.	.	H	α-helix	trans	-64	-44.1	178.9	179.4	-99.3	0	0	0	111.3	Y354 D358 S363 L364 V365	Y354-F361 HydrophobicContact CD1-CD1 4.29Å; Y354-F361 AromaticContact CE1-CD1 3.56Å; Y354-F361 HydrophobicContact CE1-CD1 3.56Å; Y354-F361 AromaticContact CE1-CE1 3.85Å; Y354-F361 HydrophobicContact CE1-CE1 3.85Å; D358-F361 WeakPolarHBondContact O-CA 3.21Å; D358-F361 WeakPolarHBondContact O-CB 3.35Å; D358-F361 PolarHBondContact O-N 2.98Å; F361-S363 VanDerWaalsContact C-N 3.31Å; F361-S363 PolarHBondContact O-N 3.4Å; F361-L364 WeakPolarHBondContact O-CB 3.17Å; F361-L364 PolarHBondContact O-N 3.38Å; F361-L364 VanDerWaalsContact O-N 3.12Å; F361-V365 HydrophobicContact CD1-CG2 4.28Å; F361-V365 HydrophobicContact CE1-CG2 3.85Å; F361-V365 HydrophobicContact CE2-CG2 4.47Å; F361-V365 HydrophobicContact CZ-CG2 3.95Å; F361-V365 WeakPolarHBondContact O-CG2 3.33Å; F361-V365 PolarHBondContact O-N 2.92Å
362	A	74.9	Confident	75.3	Confident	1 Å²	1	93.4 Å²	93.4	1%	0.008	43%	0.431	C	S	.	.	H	α-helix	trans	-60	-41.7	175.1	0	0	0	0	0	112.2	L346 Y354 D358 F359 L364 V365 H366	L346-A362 HydrophobicContact CD2-CB 3.7Å; Y354-A362 HydrophobicContact CD1-CB 3.97Å; Y354-A362 HydrophobicContact CD2-CB 3.45Å; Y354-A362 VanDerWaalsContact CD2-CB 3.45Å; Y354-A362 HydrophobicContact CE1-CB 4Å; Y354-A362 HydrophobicContact CE2-CB 3.43Å; Y354-A362 VanDerWaalsContact CE2-CB 3.43Å; Y354-A362 HydrophobicContact CG-CB 3.71Å; D358-A362 PolarHBondContact O-N 3.48Å; F359-A362 PolarHBondContact O-N 2.86Å; A362-L364 VanDerWaalsContact C-N 3.31Å; A362-L364 PolarHBondContact O-N 3.27Å; A362-V365 PolarHBondContact O-N 3.1Å; A362-H366 PolarHBondContact O-N 3.36Å
363	S	73.1	Confident	76.3	Confident	53 Å²	53	90 Å²	90	37%	0.371	42%	0.415	S	S	.	.	H	α-helix	trans	-63.6	-36.3	175.6	-58	0	0	0	0	112.3	F359 I360 F361 H366 L367	F359-S363 WeakPolarHBondContact O-CB 3.39Å; F359-S363 PolarHBondContact O-N 3.32Å; F359-S363 PolarHBondContact O-OG 3.13Å; I360-S363 PolarHBondContact O-N 3.4Å; F361-S363 VanDerWaalsContact C-N 3.31Å; F361-S363 PolarHBondContact O-N 3.4Å; S363-H366 PolarHBondContact O-N 3.22Å; S363-L367 WeakPolarHBondContact O-CB 3.47Å; S363-L367 PolarHBondContact O-N 3.27Å
364	L	78.4	Confident	76.7	Confident	104 Å²	104	84.4 Å²	84.4	55%	0.545	39%	0.393	S	S	.	.	H	α-helix	trans	-68.7	-40.5	175.7	-72.7	170.8	0	0	0	112.2	I360 F361 A362 H366 L367 F368	I360-L364 HydrophobicContact CG2-CD1 4.26Å; I360-L364 WeakPolarHBondContact O-CG 3.27Å; I360-L364 PolarHBondContact O-N 2.98Å; F361-L364 WeakPolarHBondContact O-CB 3.17Å; F361-L364 PolarHBondContact O-N 3.38Å; F361-L364 VanDerWaalsContact O-N 3.12Å; A362-L364 VanDerWaalsContact C-N 3.31Å; A362-L364 PolarHBondContact O-N 3.27Å; L364-H366 VanDerWaalsContact C-N 3.3Å; L364-H366 PolarHBondContact O-N 2.82Å; L364-L367 PolarHBondContact O-N 2.86Å; L364-F368 WeakPolarHBondContact O-CB 3.35Å; L364-F368 PolarHBondContact O-N 3.09Å
365	V	81.3	Confident	77.4	Confident	41 Å²	41	84.1 Å²	84.1	25%	0.248	40%	0.398	C	S	.	.	H	α-helix	trans	-61.3	-42.9	173.9	177	0	0	0	0	110	E342 F361 A362 L367 F368 L369	E342-V365 HydrophobicContact CG-CG1 4.38Å; E342-V365 VanDerWaalsContact OE1-C 3.29Å; E342-V365 WeakPolarHBondContact OE1-CG1 3.38Å; F361-V365 HydrophobicContact CD1-CG2 4.28Å; F361-V365 HydrophobicContact CE1-CG2 3.85Å; F361-V365 HydrophobicContact CE2-CG2 4.47Å; F361-V365 HydrophobicContact CZ-CG2 3.95Å; F361-V365 WeakPolarHBondContact O-CG2 3.33Å; F361-V365 PolarHBondContact O-N 2.92Å; A362-V365 PolarHBondContact O-N 3.1Å; V365-L367 PolarHBondContact O-N 3.27Å; V365-F368 WeakPolarHBondContact O-CB 3.43Å; V365-F368 PolarHBondContact O-N 2.89Å; V365-L369 HydrophobicContact CG1-CD1 4.25Å; V365-L369 WeakPolarHBondContact O-CG 3.38Å; V365-L369 PolarHBondContact O-N 3.27Å
366	H	78.7	Confident	78	Confident	56 Å²	56	76.4 Å²	76.4	26%	0.259	37%	0.368	S	S	.	.	H	α-helix	trans	-65.3	-44	179.9	-167.2	65.7	0	0	0	111.4	E342 A362 S363 L364 F368 L369 L370	E342-H366 WeakPolarHBondContact OE1-CA 3.25Å; E342-H366 VanDerWaalsContact OE1-CB 3.24Å; E342-H366 WeakPolarHBondContact OE1-CB 3.36Å; E342-H366 IonicContact OE1-CG 3.77Å; E342-H366 PolarHBondContact OE1-N 3.1Å; E342-H366 IonicContact OE1-ND1 2.93Å; E342-H366 IonicContact OE2-CE1 3.98Å; E342-H366 IonicContact OE2-CG 3.23Å; E342-H366 IonicContact OE2-ND1 3.05Å; E342-H366 PolarHBondContact OE2-ND1 2.91Å; A362-H366 PolarHBondContact O-N 3.36Å; S363-H366 PolarHBondContact O-N 3.22Å; L364-H366 VanDerWaalsContact C-N 3.3Å; L364-H366 PolarHBondContact O-N 2.82Å; H366-F368 VanDerWaalsContact C-N 3.31Å; H366-F368 PolarHBondContact O-N 2.95Å; H366-L369 PolarHBondContact O-N 2.99Å; H366-L370 WeakPolarHBondContact O-CB 3.43Å; H366-L370 PolarHBondContact O-N 3.48Å
367	L	79.6	Confident	78.7	Confident	96 Å²	96	64.6 Å²	64.6	50%	0.503	32%	0.324	S	S	.	.	H	α-helix	trans	-62.3	-38.8	175.4	-176.4	65.8	0	0	0	111.9	S363 L364 V365 L370 T371	S363-L367 WeakPolarHBondContact O-CB 3.47Å; S363-L367 PolarHBondContact O-N 3.27Å; L364-L367 PolarHBondContact O-N 2.86Å; V365-L367 PolarHBondContact O-N 3.27Å; L367-L370 PolarHBondContact O-N 3.47Å; L367-T371 WeakPolarHBondContact O-CB 3.37Å; L367-T371 PolarHBondContact O-N 2.84Å; L367-T371 PolarHBondContact O-OG1 3.03Å
368	F	83.8	Confident	78.9	Confident	132 Å²	132	58.7 Å²	58.7	58%	0.579	30%	0.297	S	S	*	.	H	α-helix	trans	-62.4	-48.3	175.4	176.7	-95.6	0	0	0	111.2	L364 V365 H366 L370 T371 F372	L364-F368 WeakPolarHBondContact O-CB 3.35Å; L364-F368 PolarHBondContact O-N 3.09Å; V365-F368 WeakPolarHBondContact O-CB 3.43Å; V365-F368 PolarHBondContact O-N 2.89Å; H366-F368 VanDerWaalsContact C-N 3.31Å; H366-F368 PolarHBondContact O-N 2.95Å; F368-L370 VanDerWaalsContact C-N 3.34Å; F368-L370 PolarHBondContact O-N 3.35Å; F368-T371 PolarHBondContact O-N 3.09Å; F368-F372 WeakPolarHBondContact O-CB 3.14Å; F368-F372 PolarHBondContact O-N 3.24Å
369	L	83.7	Confident	78.8	Confident	15 Å²	15	56.9 Å²	56.9	8%	0.079	29%	0.288	C	S	.	.	H	α-helix	trans	-63.2	-39.9	177.5	-70.5	173.4	0	0	0	112.3	A338 E342 V365 H366 F372 S373	A338-L369 HydrophobicContact CB-CD1 4.17Å; A338-L369 HydrophobicContact CB-CD2 3.52Å; E342-L369 HydrophobicContact CB-CD1 4.15Å; E342-L369 WeakPolarHBondContact OE2-CD1 3.49Å; V365-L369 HydrophobicContact CG1-CD1 4.25Å; V365-L369 WeakPolarHBondContact O-CG 3.38Å; V365-L369 PolarHBondContact O-N 3.27Å; H366-L369 PolarHBondContact O-N 2.99Å; L369-F372 PolarHBondContact O-N 3.35Å; L369-S373 WeakPolarHBondContact O-CB 3.44Å; L369-S373 PolarHBondContact O-N 3.13Å
370	L	81.8	Confident	79.1	Confident	28 Å²	28	51.1 Å²	51.1	15%	0.147	26%	0.263	C	S	.	.	H	α-helix	trans	-59.6	-48.4	173.8	-167.1	79	0	0	0	110.9	W270 T273 S277 H366 L367 F368 F372 S373 Y374	W270-L370 HydrophobicContact CZ3-CD2 4.15Å; W270-L370 HydrophobicContact CZ3-CG 4.42Å; T273-L370 HydrophobicContact CG2-CD1 3.47Å; T273-L370 VanDerWaalsContact CG2-CD1 3.47Å; T273-L370 HydrophobicContact CG2-CG 3.69Å; T273-L370 WeakPolarHBondContact CG2-O 3.43Å; S277-L370 WeakPolarHBondContact OG-CD1 3.45Å; H366-L370 WeakPolarHBondContact O-CB 3.43Å; H366-L370 PolarHBondContact O-N 3.48Å; L367-L370 PolarHBondContact O-N 3.47Å; F368-L370 VanDerWaalsContact C-N 3.34Å; F368-L370 PolarHBondContact O-N 3.35Å; L370-F372 VanDerWaalsContact C-N 3.32Å; L370-F372 PolarHBondContact O-N 3.14Å; L370-S373 WeakPolarHBondContact O-CB 3.4Å; L370-S373 PolarHBondContact O-N 2.91Å; L370-Y374 PolarHBondContact O-N 3.01Å
371	T	81.7	Confident	79.1	Confident	70 Å²	70	45.5 Å²	45.5	43%	0.429	23%	0.234	S	C	.	.	H	α-helix	trans	-65.5	-37.2	-179.4	-52.6	0	0	0	0	111.8	L367 F368 S373 Y374 S375	L367-T371 WeakPolarHBondContact O-CB 3.37Å; L367-T371 PolarHBondContact O-N 2.84Å; L367-T371 PolarHBondContact O-OG1 3.03Å; F368-T371 PolarHBondContact O-N 3.09Å; T371-S373 VanDerWaalsContact C-N 3.35Å; T371-Y374 WeakPolarHBondContact O-CB 3.39Å; T371-Y374 PolarHBondContact O-N 3.19Å; T371-S375 PolarHBondContact O-N 3.35Å
372	F	82.5	Confident	78.5	Confident	66 Å²	66	43.5 Å²	43.5	29%	0.289	23%	0.229	S	C	.	.	H	α-helix	trans	-69.8	-34	176.1	-149.9	-121.2	0	0	0	111.7	V331 I334 I335 F368 L369 L370 S375 G376	V331-F372 HydrophobicContact CG1-CD1 3.77Å; V331-F372 HydrophobicContact CG1-CE1 3.8Å; V331-F372 HydrophobicContact CG1-CG 4.27Å; V331-F372 HydrophobicContact CG1-CZ 4.34Å; V331-F372 WeakPolarHBondContact CG1-O 3.37Å; V331-F372 HydrophobicContact CG2-CE1 4.48Å; V331-F372 HydrophobicContact CG2-CZ 4.46Å; I334-F372 HydrophobicContact CD1-CE1 4.36Å; I334-F372 HydrophobicContact CG2-CE1 4.34Å; I335-F372 HydrophobicContact CD1-CB 3.96Å; I335-F372 HydrophobicContact CD1-CD1 3.7Å; I335-F372 HydrophobicContact CD1-CG 4.2Å; I335-F372 WeakPolarHBondContact CD1-O 3.44Å; I335-F372 HydrophobicContact CG1-CB 4.28Å; I335-F372 HydrophobicContact CG1-CD1 3.68Å; I335-F372 HydrophobicContact CG1-CG 4.45Å; F368-F372 WeakPolarHBondContact O-CB 3.14Å; F368-F372 PolarHBondContact O-N 3.24Å; L369-F372 PolarHBondContact O-N 3.35Å; L370-F372 VanDerWaalsContact C-N 3.32Å; L370-F372 PolarHBondContact O-N 3.14Å; F372-S375 PolarHBondContact O-N 2.88Å; F372-S375 PolarHBondContact O-OG 3.43Å; F372-G376 PolarHBondContact O-N 3.26Å
373	S	84.6	Confident	77.6	Confident	3 Å²	3	48.8 Å²	48.8	2%	0.021	25%	0.252	C	S	.	.	H	α-helix	trans	-65.4	-45	174.4	-173.1	0	0	0	0	111	L369 L370 T371 S375 G376 F377	L369-S373 WeakPolarHBondContact O-CB 3.44Å; L369-S373 PolarHBondContact O-N 3.13Å; L370-S373 WeakPolarHBondContact O-CB 3.4Å; L370-S373 PolarHBondContact O-N 2.91Å; T371-S373 VanDerWaalsContact C-N 3.35Å; S373-S375 VanDerWaalsContact C-N 3.33Å; S373-S375 PolarHBondContact O-N 3.04Å; S373-G376 PolarHBondContact O-N 2.97Å; S373-G376 VanDerWaalsContact O-N 3.12Å; S373-F377 VanDerWaalsContact O-CD2 3.25Å; S373-F377 WeakPolarHBondContact O-CD2 3.3Å; S373-F377 PolarHBondContact O-N 3.06Å
374	Y	80.9	Confident	76.7	Confident	39 Å²	39	47.2 Å²	47.2	15%	0.153	24%	0.239	C	C	.	.	H	α-helix	trans	-57.2	-45.3	173.7	175.4	-116.5	0	0	0	112	I266 W270 T273 L370 T371 G376 F377 I378	I266-Y374 VanDerWaalsContact CG2-OH 3.27Å; I266-Y374 WeakPolarHBondContact CG2-OH 3.35Å; W270-Y374 HydrophobicContact CB-CD2 4.47Å; W270-Y374 HydrophobicContact CB-CE2 4.4Å; W270-Y374 AromaticContact CD1-CD2 3.86Å; W270-Y374 AromaticContact CD1-CE2 3.17Å; W270-Y374 AromaticContact CD1-CZ 3.57Å; W270-Y374 AromaticContact CD2-CD2 3.69Å; W270-Y374 HydrophobicContact CD2-CD2 3.69Å; W270-Y374 AromaticContact CD2-CE2 3.82Å; W270-Y374 HydrophobicContact CD2-CE2 3.82Å; W270-Y374 HydrophobicContact CD2-CG 4.14Å; W270-Y374 AromaticContact CE2-CD1 3.97Å; W270-Y374 AromaticContact CE2-CD2 3.74Å; W270-Y374 AromaticContact CE2-CE1 3.81Å; W270-Y374 AromaticContact CE2-CE2 3.6Å; W270-Y374 AromaticContact CE2-CG 3.93Å; W270-Y374 AromaticContact CE2-CZ 3.63Å; W270-Y374 HydrophobicContact CE3-CD2 4.26Å; W270-Y374 HydrophobicContact CE3-CG 4.43Å; W270-Y374 AromaticContact CG-CD2 3.79Å; W270-Y374 HydrophobicContact CG-CD2 3.79Å; W270-Y374 AromaticContact CG-CE2 3.58Å; W270-Y374 HydrophobicContact CG-CE2 3.58Å; W270-Y374 HydrophobicContact CH2-CD1 4.32Å; W270-Y374 HydrophobicContact CH2-CG 4.34Å; W270-Y374 AromaticContact CZ2-CD1 3.8Å; W270-Y374 HydrophobicContact CZ2-CD1 3.8Å; W270-Y374 HydrophobicContact CZ2-CD2 4.32Å; W270-Y374 AromaticContact CZ2-CE1 3.84Å; W270-Y374 HydrophobicContact CZ2-CE1 3.84Å; W270-Y374 HydrophobicContact CZ2-CE2 4.39Å; W270-Y374 HydrophobicContact CZ2-CG 4.04Å; W270-Y374 AromaticContact NE1-CD2 3.83Å; W270-Y374 AromaticContact NE1-CE1 3.7Å; W270-Y374 AromaticContact NE1-CE2 3.19Å; W270-Y374 AromaticContact NE1-CZ 3.1Å; W270-Y374 PolarHBondContact NE1-OH 3.49Å; T273-Y374 WeakPolarHBondContact OG1-CA 3.44Å; T273-Y374 PolarHBondContact OG1-N 3.35Å; L370-Y374 PolarHBondContact O-N 3.01Å; T371-Y374 WeakPolarHBondContact O-CB 3.39Å; T371-Y374 PolarHBondContact O-N 3.19Å; Y374-G376 VanDerWaalsContact C-N 3.34Å; Y374-G376 PolarHBondContact O-N 2.99Å; Y374-F377 PolarHBondContact O-N 2.71Å; Y374-I378 HydrophobicContact CD1-CD1 3.57Å; Y374-I378 HydrophobicContact CD2-CD1 4.02Å; Y374-I378 HydrophobicContact CD2-CG1 4.13Å; Y374-I378 HydrophobicContact CE1-CD1 3.11Å; Y374-I378 HydrophobicContact CE1-CG1 4.17Å; Y374-I378 HydrophobicContact CE2-CD1 3.6Å; Y374-I378 HydrophobicContact CE2-CG1 3.72Å; Y374-I378 HydrophobicContact CG-CD1 3.99Å; Y374-I378 HydrophobicContact CG-CG1 4.49Å; Y374-I378 VanDerWaalsContact O-CG1 3.26Å; Y374-I378 WeakPolarHBondContact O-CG1 3.49Å; Y374-I378 PolarHBondContact O-N 2.9Å; Y374-I378 WeakPolarHBondContact OH-CD1 3.24Å
375	S	81.2	Confident	75	Confident	41 Å²	41	51.1 Å²	51.1	29%	0.287	25%	0.251	S	S	.	.	H	α-helix	trans	-64.8	-37	176.3	71.5	0	0	0	0	112.6	T371 F372 S373 I378 V379	T371-S375 PolarHBondContact O-N 3.35Å; F372-S375 PolarHBondContact O-N 2.88Å; F372-S375 PolarHBondContact O-OG 3.43Å; S373-S375 VanDerWaalsContact C-N 3.33Å; S373-S375 PolarHBondContact O-N 3.04Å; S375-I378 PolarHBondContact O-N 3.2Å; S375-V379 WeakPolarHBondContact O-CB 3.4Å; S375-V379 VanDerWaalsContact O-CG2 3.22Å; S375-V379 WeakPolarHBondContact O-CG2 3.14Å; S375-V379 PolarHBondContact O-N 3.31Å
376	G	79.6	Confident	72.9	Confident	0 Å²	0	51.9 Å²	51.9	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-59.2	-46.7	173.5	0	0	0	0	0	113	G328 F372 S373 Y374 V379 M380	G328-G376 VanDerWaalsContact CA-O 3.3Å; G328-G376 WeakPolarHBondContact CA-O 3.44Å; F372-G376 PolarHBondContact O-N 3.26Å; S373-G376 PolarHBondContact O-N 2.97Å; S373-G376 VanDerWaalsContact O-N 3.12Å; Y374-G376 VanDerWaalsContact C-N 3.34Å; Y374-G376 PolarHBondContact O-N 2.99Å; G376-V379 PolarHBondContact O-N 3.38Å; G376-M380 WeakPolarHBondContact O-CB 3.46Å; G376-M380 PolarHBondContact O-N 3.33Å
377	F	80.1	Confident	70.8	Confident	0 Å²	0	56 Å²	56	0%	0	29%	0.286	C	S	.	.	H	α-helix	trans	-66.6	-44.9	175.8	-76.1	-64.1	0	0	0	112.5	F55 F59 L272 T273 L276 L332 S373 Y374 V379 M380 F381	F55-F377 HydrophobicContact CE2-CE1 4.43Å; F55-F377 AromaticContact CE2-CZ 3.75Å; F55-F377 HydrophobicContact CE2-CZ 3.75Å; F55-F377 HydrophobicContact CZ-CE1 4.35Å; F55-F377 AromaticContact CZ-CZ 3.87Å; F55-F377 HydrophobicContact CZ-CZ 3.87Å; F59-F377 HydrophobicContact CD2-CE1 4.44Å; L272-F377 HydrophobicContact CB-CD1 4.18Å; L272-F377 HydrophobicContact CB-CD2 4.11Å; L272-F377 HydrophobicContact CB-CE1 3.97Å; L272-F377 HydrophobicContact CB-CE2 3.88Å; L272-F377 HydrophobicContact CB-CG 4.26Å; L272-F377 HydrophobicContact CB-CZ 3.82Å; L272-F377 HydrophobicContact CD1-CD1 3.86Å; L272-F377 HydrophobicContact CD1-CE1 3.88Å; L272-F377 HydrophobicContact CG-CE1 4.47Å; T273-F377 WeakPolarHBondContact OG1-CD2 3.37Å; L276-F377 HydrophobicContact CD2-CE2 3.94Å; L276-F377 HydrophobicContact CD2-CZ 3.95Å; L332-F377 HydrophobicContact CD1-CD1 4.44Å; L332-F377 HydrophobicContact CD1-CE1 3.93Å; L332-F377 HydrophobicContact CD1-CZ 4.06Å; L332-F377 HydrophobicContact CD2-CD2 4.29Å; L332-F377 HydrophobicContact CD2-CE2 3.87Å; L332-F377 HydrophobicContact CD2-CZ 4Å; S373-F377 VanDerWaalsContact O-CD2 3.25Å; S373-F377 WeakPolarHBondContact O-CD2 3.3Å; S373-F377 PolarHBondContact O-N 3.06Å; Y374-F377 PolarHBondContact O-N 2.71Å; F377-V379 VanDerWaalsContact C-N 3.28Å; F377-V379 PolarHBondContact O-N 3.36Å; F377-M380 WeakPolarHBondContact O-CB 3.47Å; F377-M380 PolarHBondContact O-N 3.32Å; F377-M380 VanDerWaalsContact O-N 3.11Å; F377-F381 HydrophobicContact CB-CD2 4.32Å; F377-F381 HydrophobicContact CB-CE2 4.05Å; F377-F381 AromaticContact CD1-CE2 4Å; F377-F381 HydrophobicContact CD1-CE2 4Å; F377-F381 HydrophobicContact CD1-CZ 4.38Å; F377-F381 HydrophobicContact CG-CE2 4.45Å; F377-F381 WeakPolarHBondContact O-CD2 2.99Å; F377-F381 WeakPolarHBondContact O-CG 3.48Å; F377-F381 PolarHBondContact O-N 3.3Å
378	I	76.4	Confident	70.3	Confident	44 Å²	44	54.1 Å²	54.1	23%	0.226	28%	0.275	C	S	.	.	H	α-helix	trans	-57.9	-44.4	176.1	-67.7	163.5	0	0	0	110.6	Y374 S375 M380 F381 L382	Y374-I378 HydrophobicContact CD1-CD1 3.57Å; Y374-I378 HydrophobicContact CD2-CD1 4.02Å; Y374-I378 HydrophobicContact CD2-CG1 4.13Å; Y374-I378 HydrophobicContact CE1-CD1 3.11Å; Y374-I378 HydrophobicContact CE1-CG1 4.17Å; Y374-I378 HydrophobicContact CE2-CD1 3.6Å; Y374-I378 HydrophobicContact CE2-CG1 3.72Å; Y374-I378 HydrophobicContact CG-CD1 3.99Å; Y374-I378 HydrophobicContact CG-CG1 4.49Å; Y374-I378 VanDerWaalsContact O-CG1 3.26Å; Y374-I378 WeakPolarHBondContact O-CG1 3.49Å; Y374-I378 PolarHBondContact O-N 2.9Å; Y374-I378 WeakPolarHBondContact OH-CD1 3.24Å; S375-I378 PolarHBondContact O-N 3.2Å; I378-M380 VanDerWaalsContact C-N 3.31Å; I378-M380 PolarHBondContact O-N 3.26Å; I378-F381 CarbonylContact O-C 3.47Å; I378-F381 PolarHBondContact O-N 2.68Å; I378-L382 HydrophobicContact CG2-CD1 3.46Å; I378-L382 VanDerWaalsContact CG2-CD1 3.46Å; I378-L382 HydrophobicContact CG2-CG 3.87Å; I378-L382 WeakPolarHBondContact O-CA 3.46Å; I378-L382 WeakPolarHBondContact O-CB 3.35Å; I378-L382 VanDerWaalsContact O-CG 3.26Å; I378-L382 WeakPolarHBondContact O-CG 3.42Å; I378-L382 PolarHBondContact O-N 3.47Å
379	V	74.9	Confident	69.6	Low	23 Å²	23	49.9 Å²	49.9	14%	0.139	26%	0.259	C	S	.	.	H	α-helix	trans	-64.5	-37.9	178	173.7	0	0	0	0	111.5	T324 I327 S375 G376 F377 F381 L382	T324-V379 HydrophobicContact CG2-CG1 4.17Å; T324-V379 WeakPolarHBondContact CG2-O 2.95Å; T324-V379 WeakPolarHBondContact O-CG1 3.1Å; I327-V379 HydrophobicContact CB-CG1 3.81Å; I327-V379 HydrophobicContact CG2-CG1 3.81Å; S375-V379 WeakPolarHBondContact O-CB 3.4Å; S375-V379 VanDerWaalsContact O-CG2 3.22Å; S375-V379 WeakPolarHBondContact O-CG2 3.14Å; S375-V379 PolarHBondContact O-N 3.31Å; G376-V379 PolarHBondContact O-N 3.38Å; F377-V379 VanDerWaalsContact C-N 3.28Å; F377-V379 PolarHBondContact O-N 3.36Å; V379-F381 VanDerWaalsContact C-N 3.27Å; V379-F381 PolarHBondContact O-N 3.38Å; V379-L382 HydrophobicContact CG2-CD1 4.16Å; V379-L382 PolarHBondContact O-N 3.12Å
380	M	75.7	Confident	68.8	Low	11 Å²	11	51.9 Å²	51.9	5%	0.054	27%	0.269	C	S	.	.	H	α-helix	trans	-63.7	-33.5	174.6	-164.9	178.7	-60.2	0	0	112.5	F59 P329 L332 G376 F377 I378	F59-M380 HydrophobicContact CE2-SD 3.7Å; F59-M380 HydrophobicContact CZ-SD 4.12Å; P329-M380 HydrophobicContact CG-CE 3.87Å; L332-M380 HydrophobicContact CD1-CE 3.57Å; G376-M380 WeakPolarHBondContact O-CB 3.46Å; G376-M380 PolarHBondContact O-N 3.33Å; F377-M380 WeakPolarHBondContact O-CB 3.47Å; F377-M380 PolarHBondContact O-N 3.32Å; F377-M380 VanDerWaalsContact O-N 3.11Å; I378-M380 VanDerWaalsContact C-N 3.31Å; I378-M380 PolarHBondContact O-N 3.26Å
381	F	70.9	Confident	68.1	Low	9 Å²	9	53.3 Å²	53.3	4%	0.039	28%	0.276	C	S	.	.	H	α-helix	trans	-95.3	-9.4	179.2	-57.1	-52.6	0	0	0	114.2	A62 F265 I268 S269 L272 F377 I378 V379 I384	A62-F381 HydrophobicContact CB-CE1 3.73Å; A62-F381 HydrophobicContact CB-CZ 3.76Å; F265-F381 HydrophobicContact CB-CB 4.25Å; F265-F381 HydrophobicContact CD1-CB 3.8Å; F265-F381 HydrophobicContact CD1-CD1 4.24Å; F265-F381 AromaticContact CD1-CG 3.97Å; F265-F381 HydrophobicContact CD1-CG 3.97Å; F265-F381 HydrophobicContact CE1-CB 4.5Å; F265-F381 HydrophobicContact CE1-CD1 4.43Å; F265-F381 HydrophobicContact CG-CB 4.23Å; I268-F381 HydrophobicContact CG2-CE2 3.98Å; I268-F381 HydrophobicContact CG2-CZ 4.23Å; S269-F381 WeakPolarHBondContact OG-CD2 3.06Å; L272-F381 HydrophobicContact CD1-CE2 3.83Å; L272-F381 HydrophobicContact CD1-CZ 3.77Å; F377-F381 HydrophobicContact CB-CD2 4.32Å; F377-F381 HydrophobicContact CB-CE2 4.05Å; F377-F381 AromaticContact CD1-CE2 4Å; F377-F381 HydrophobicContact CD1-CE2 4Å; F377-F381 HydrophobicContact CD1-CZ 4.38Å; F377-F381 HydrophobicContact CG-CE2 4.45Å; F377-F381 WeakPolarHBondContact O-CD2 2.99Å; F377-F381 WeakPolarHBondContact O-CG 3.48Å; F377-F381 PolarHBondContact O-N 3.3Å; I378-F381 CarbonylContact O-C 3.47Å; I378-F381 PolarHBondContact O-N 2.68Å; V379-F381 VanDerWaalsContact C-N 3.27Å; V379-F381 PolarHBondContact O-N 3.38Å; F381-I384 HydrophobicContact CB-CD1 4.01Å; F381-I384 HydrophobicContact CD1-CD1 3.77Å; F381-I384 HydrophobicContact CG-CD1 4.38Å; F381-I384 WeakPolarHBondContact O-CG1 3.34Å; F381-I384 PolarHBondContact O-N 3.41Å
382	L	65.2	Low	67.2	Low	82 Å²	82	52.3 Å²	52.3	43%	0.429	27%	0.266	S	S	.	.	T	Hydrogen-bonded Turn	trans	-68.7	130.3	179	-100.9	158	0	0	0	110.1	T324 I378 V379 I384	T324-L382 HydrophobicContact CG2-CB 4.18Å; I378-L382 HydrophobicContact CG2-CD1 3.46Å; I378-L382 VanDerWaalsContact CG2-CD1 3.46Å; I378-L382 HydrophobicContact CG2-CG 3.87Å; I378-L382 WeakPolarHBondContact O-CA 3.46Å; I378-L382 WeakPolarHBondContact O-CB 3.35Å; I378-L382 VanDerWaalsContact O-CG 3.26Å; I378-L382 WeakPolarHBondContact O-CG 3.42Å; I378-L382 PolarHBondContact O-N 3.47Å; V379-L382 HydrophobicContact CG2-CD1 4.16Å; V379-L382 PolarHBondContact O-N 3.12Å; L382-I384 VanDerWaalsContact C-N 3.33Å
383	K	56.3	Low	66.2	Low	112 Å²	112	51.3 Å²	51.3	49%	0.487	27%	0.265	S	S	.	.	T	Hydrogen-bonded Turn	trans	70.1	17.2	-176	-58	-172.4	174.1	-178.8	0	115.7	K385	K383-K385 PolarHBondContact O-N 3.38Å
384	I	54	Low	64.9	Low	20 Å²	20	54.8 Å²	54.8	10%	0.103	28%	0.282	C	S	.	.			trans	-66.2	93.9	153.9	-62.9	167.5	0	0	0	106.5	A66 F265 W325 F381 L382 L386	A66-I384 HydrophobicContact CB-CD1 3.31Å; A66-I384 HydrophobicContact CB-CG1 3.94Å; A66-I384 HydrophobicContact CB-CG2 4.1Å; F265-I384 HydrophobicContact CE1-CD1 3.99Å; F265-I384 HydrophobicContact CE2-CG2 4.46Å; F265-I384 HydrophobicContact CZ-CB 4.38Å; F265-I384 HydrophobicContact CZ-CD1 4.24Å; F265-I384 HydrophobicContact CZ-CG2 3.99Å; W325-I384 HydrophobicContact CH2-CD1 3.98Å; W325-I384 HydrophobicContact CH2-CG1 3.64Å; W325-I384 HydrophobicContact CZ2-CG1 3.79Å; F381-I384 HydrophobicContact CB-CD1 4.01Å; F381-I384 HydrophobicContact CD1-CD1 3.77Å; F381-I384 HydrophobicContact CG-CD1 4.38Å; F381-I384 WeakPolarHBondContact O-CG1 3.34Å; F381-I384 PolarHBondContact O-N 3.41Å; L382-I384 VanDerWaalsContact C-N 3.33Å; I384-L386 HydrophobicContact CG2-CG 4.49Å; I384-L386 PolarHBondContact O-N 3Å
385	K	42	Very low	63.6	Low	186 Å²	186	56 Å²	56	81%	0.809	29%	0.292	S	S	*	.			trans	-74.3	104.9	162.7	-80	-172.6	173.5	-172.7	0	105.9	K383	K383-K385 PolarHBondContact O-N 3.38Å
386	L	37.7	Very low	62.2	Low	57 Å²	57	57.3 Å²	57.3	30%	0.298	29%	0.293	S	S	.	.			trans	-66.8	134.8	156.9	-86.8	138.7	0	0	0	107.4	Y65 V261 F265 I384	Y65-L386 WeakPolarHBondContact O-CD2 3.44Å; V261-L386 HydrophobicContact CG1-CD1 3.26Å; V261-L386 HydrophobicContact CG1-CG 4.5Å; F265-L386 HydrophobicContact CE2-CD1 3.72Å; F265-L386 HydrophobicContact CZ-CD1 3.8Å; I384-L386 HydrophobicContact CG2-CG 4.49Å; I384-L386 PolarHBondContact O-N 3Å
387	P	33.3	Very low	60.6	Low	143 Å²	143	62.5 Å²	62.5	93%	0.929	32%	0.319	S	S	*	.			trans	-59.7	0	176	22.4	-33.3	0	0	0	112.6	D68	D68-P387 HydrophobicContact CB-CG 4.31Å; D68-P387 WeakPolarHBondContact OD1-CD 3.44Å

Retrieved 387 of 387 residues in 430.7 ms (Link to these results)

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