A0A5K4FC63_SCHMA Loading...

VHS domain-containing protein

AlphaFold DB , UniProt , Accession A0A5K4FC63, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 281 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	54.4	Low	58.5	Low	140 Å²	140	87.8 Å²	87.8	69%	0.69	41%	0.408	S	S	*	.				0	-51	0	-141.6	179	-63.3	0	0	112.7	K3 I4 M268	M1-K3 PolarHBondContact O-N 3.07Å; M1-I4 HydrophobicContact CG-CD1 4.45Å; M1-I4 VanDerWaalsContact O-CB 3.32Å; M1-I4 WeakPolarHBondContact O-CB 3.31Å; M1-I4 PolarHBondContact O-N 3.03Å; M1-M268 HydrophobicContact CB-CE 3.68Å; M1-M268 HydrophobicContact CB-SD 4.03Å; M1-M268 HydrophobicContact CG-CE 3.49Å; M1-M268 VanDerWaalsContact CG-CE 3.49Å; M1-M268 HydrophobicContact CG-SD 3.53Å; M1-M268 VanDerWaalsContact CG-SD 3.53Å; M1-M268 HydrophobicContact SD-CE 3.12Å; M1-M268 WeakPolarHBondContact SD-CE 3.25Å; M1-M268 HydrophobicContact SD-SD 3.7Å
2	L	57.3	Low	58.2	Low	109 Å²	109	80.8 Å²	80.8	57%	0.571	38%	0.376	S	S	*	.	H	α-helix	trans	-54.9	-38.7	170.9	-149.2	92.3	0	0	0	112.9	I4 I5 I6	L2-I4 VanDerWaalsContact C-N 3.28Å; L2-I4 PolarHBondContact O-N 3.27Å; L2-I5 WeakPolarHBondContact O-CB 3.32Å; L2-I5 PolarHBondContact O-N 3.31Å; L2-I5 VanDerWaalsContact O-N 3.13Å; L2-I6 HydrophobicContact CD2-CD1 4.32Å; L2-I6 WeakPolarHBondContact O-CG1 3.24Å; L2-I6 PolarHBondContact O-N 2.97Å; L2-I6 VanDerWaalsContact O-N 3.1Å
3	K	59.3	Low	58.2	Low	165 Å²	165	81.5 Å²	81.5	72%	0.717	38%	0.379	S	S	*	.	H	α-helix	trans	-52.3	-41.9	171.6	-71.1	-175	176.4	-177.8	0	113	M1 I5 I6 D7	M1-K3 PolarHBondContact O-N 3.07Å; K3-I5 VanDerWaalsContact C-N 3.32Å; K3-I5 PolarHBondContact O-N 2.88Å; K3-I6 PolarHBondContact O-N 3.1Å; K3-D7 VanDerWaalsContact O-CG 3.26Å; K3-D7 PolarHBondContact O-N 3Å
4	I	55.7	Low	58.2	Low	40 Å²	40	83.4 Å²	83.4	21%	0.205	39%	0.388	C	S	.	.	H	α-helix	trans	-62.7	-40.2	179.7	-59.7	171.2	0	0	0	110.9	M1 L2 H8 L272 M275 F277	M1-I4 HydrophobicContact CG-CD1 4.45Å; M1-I4 VanDerWaalsContact O-CB 3.32Å; M1-I4 WeakPolarHBondContact O-CB 3.31Å; M1-I4 PolarHBondContact O-N 3.03Å; L2-I4 VanDerWaalsContact C-N 3.28Å; L2-I4 PolarHBondContact O-N 3.27Å; I4-H8 VanDerWaalsContact O-CB 3.32Å; I4-H8 WeakPolarHBondContact O-CB 3.46Å; I4-H8 PolarHBondContact O-N 2.8Å; I4-L272 HydrophobicContact CG2-CD2 4.4Å; I4-M275 HydrophobicContact CG2-SD 3.98Å; I4-F277 HydrophobicContact CD1-CE2 4.19Å; I4-F277 HydrophobicContact CD1-CZ 3.85Å
5	I	52.7	Low	58.4	Low	4 Å²	4	87.8 Å²	87.8	2%	0.021	41%	0.406	C	S	.	.	H	α-helix	trans	-64.9	-46.4	176.8	-65.8	171.2	0	0	0	110.1	L2 K3 H8 R9 L267 M268 L272	L2-I5 WeakPolarHBondContact O-CB 3.32Å; L2-I5 PolarHBondContact O-N 3.31Å; L2-I5 VanDerWaalsContact O-N 3.13Å; K3-I5 VanDerWaalsContact C-N 3.32Å; K3-I5 PolarHBondContact O-N 2.88Å; I5-H8 PolarHBondContact O-N 2.96Å; I5-R9 HydrophobicContact CG2-CG 4.48Å; I5-R9 WeakPolarHBondContact O-CG 3.12Å; I5-R9 PolarHBondContact O-N 3.07Å; I5-L267 HydrophobicContact CD1-CB 4.45Å; I5-M268 HydrophobicContact CD1-CG 3.66Å; I5-M268 HydrophobicContact CD1-SD 3.6Å; I5-M268 HydrophobicContact CG1-SD 4.42Å; I5-L272 HydrophobicContact CD1-CD1 4.17Å; I5-L272 HydrophobicContact CG1-CD1 3.74Å
6	I	62	Low	58.3	Low	95 Å²	95	83 Å²	83	49%	0.487	39%	0.385	S	S	.	.	H	α-helix	trans	-60.3	-48.6	178.9	-64.7	168.4	0	0	0	110.4	L2 K3 H8 R9 K10	L2-I6 HydrophobicContact CD2-CD1 4.32Å; L2-I6 WeakPolarHBondContact O-CG1 3.24Å; L2-I6 PolarHBondContact O-N 2.97Å; L2-I6 VanDerWaalsContact O-N 3.1Å; K3-I6 PolarHBondContact O-N 3.1Å; I6-H8 VanDerWaalsContact C-N 3.3Å; I6-H8 PolarHBondContact O-N 2.87Å; I6-R9 PolarHBondContact O-N 3.19Å; I6-K10 PolarHBondContact O-N 3.38Å
7	D	61.7	Low	58	Low	87 Å²	87	80.3 Å²	80.3	47%	0.465	38%	0.377	S	S	.	.	H	α-helix	trans	-63.4	-35.6	178.7	-66.9	-23.8	0	0	0	112.3	K3 R11	K3-D7 VanDerWaalsContact O-CG 3.26Å; K3-D7 PolarHBondContact O-N 3Å; D7-R11 WeakPolarHBondContact O-CG 3.44Å; D7-R11 PolarHBondContact O-N 3.1Å; D7-R11 VanDerWaalsContact O-N 3.15Å; D7-R11 PolarHBondContact O-NE 3.26Å
8	H	58.3	Low	57.8	Low	37 Å²	37	83.1 Å²	83.1	17%	0.171	39%	0.39	C	S	.	.	H	α-helix	trans	-70.6	-41.1	175.8	-161.3	75.7	0	0	0	112	I4 I5 I6 K10 R11 V12 C245	I4-H8 VanDerWaalsContact O-CB 3.32Å; I4-H8 WeakPolarHBondContact O-CB 3.46Å; I4-H8 PolarHBondContact O-N 2.8Å; I5-H8 PolarHBondContact O-N 2.96Å; I6-H8 VanDerWaalsContact C-N 3.3Å; I6-H8 PolarHBondContact O-N 2.87Å; H8-K10 VanDerWaalsContact C-N 3.33Å; H8-K10 PolarHBondContact O-N 2.81Å; H8-R11 PolarHBondContact O-N 3.13Å; H8-V12 WeakPolarHBondContact O-CG2 3.32Å; H8-V12 PolarHBondContact O-N 3.12Å; H8-C245 VanDerWaalsContact CD2-SG 3.58Å
9	R	61.2	Low	57.6	Low	40 Å²	40	81.1 Å²	81.1	15%	0.151	39%	0.388	C	S	.	.	H	α-helix	trans	-60.1	-43.1	174.2	-74.6	-177.2	-176.1	165.7	4.8	111.8	I5 I6 V12 Q13 T249 N264	I5-R9 HydrophobicContact CG2-CG 4.48Å; I5-R9 WeakPolarHBondContact O-CG 3.12Å; I5-R9 PolarHBondContact O-N 3.07Å; I6-R9 PolarHBondContact O-N 3.19Å; R9-V12 PolarHBondContact O-N 3.44Å; R9-Q13 PolarHBondContact O-N 3.47Å; R9-T249 WeakPolarHBondContact CB-OG1 3.39Å; R9-T249 WeakPolarHBondContact CG-OG1 3.36Å; R9-N264 PolarHBondContact NH2-OD1 3.23Å
10	K	63	Low	57.3	Low	124 Å²	124	78.1 Å²	78.1	54%	0.539	37%	0.373	S	S	.	.	H	α-helix	trans	-58.7	-48.5	175.7	-168.7	-176.9	177.3	-173.1	0	111.8	I6 H8 V12 Q13 E14	I6-K10 PolarHBondContact O-N 3.38Å; H8-K10 VanDerWaalsContact C-N 3.33Å; H8-K10 PolarHBondContact O-N 2.81Å; K10-V12 VanDerWaalsContact C-N 3.33Å; K10-V12 PolarHBondContact O-N 2.97Å; K10-Q13 WeakPolarHBondContact O-CB 3.41Å; K10-Q13 PolarHBondContact O-N 3.23Å; K10-E14 WeakPolarHBondContact CE-OE1 3.18Å; K10-E14 WeakPolarHBondContact O-CG 3.37Å; K10-E14 PolarHBondContact O-N 3.37Å
11	R	58.1	Low	57.2	Low	125 Å²	125	78.4 Å²	78.4	47%	0.472	38%	0.377	S	S	.	.	H	α-helix	trans	-61.5	-37.8	176.6	-76.5	-176.9	-71.1	-165.8	-3.2	113.4	D7 H8 K15	D7-R11 WeakPolarHBondContact O-CG 3.44Å; D7-R11 PolarHBondContact O-N 3.1Å; D7-R11 VanDerWaalsContact O-N 3.15Å; D7-R11 PolarHBondContact O-NE 3.26Å; H8-R11 PolarHBondContact O-N 3.13Å; R11-K15 WeakPolarHBondContact O-CG 3.34Å; R11-K15 PolarHBondContact O-N 2.82Å; R11-K15 VanDerWaalsContact O-N 3.1Å
12	V	55.3	Low	57.2	Low	3 Å²	3	77.9 Å²	77.9	2%	0.018	37%	0.373	C	S	.	.	H	α-helix	trans	-63.4	-46.7	175.6	167.1	0	0	0	0	110.2	H8 R9 K10 E14 K15 T16 T246	H8-V12 WeakPolarHBondContact O-CG2 3.32Å; H8-V12 PolarHBondContact O-N 3.12Å; R9-V12 PolarHBondContact O-N 3.44Å; K10-V12 VanDerWaalsContact C-N 3.33Å; K10-V12 PolarHBondContact O-N 2.97Å; V12-E14 PolarHBondContact O-N 3.33Å; V12-K15 PolarHBondContact O-N 3.5Å; V12-T16 HydrophobicContact CG1-CG2 4.46Å; V12-T16 PolarHBondContact O-N 2.83Å; V12-T16 PolarHBondContact O-OG1 3.32Å; V12-T16 VanDerWaalsContact O-OG1 3.09Å; V12-T246 HydrophobicContact CG1-CG2 3.97Å; V12-T246 WeakPolarHBondContact CG1-OG1 3.41Å
13	Q	57.8	Low	57.2	Low	90 Å²	90	75.1 Å²	75.1	42%	0.421	36%	0.356	S	S	.	.	H	α-helix	trans	-58.9	-45.4	177.8	-168.9	176.9	2.4	0	0	112	R9 K10 K15 T16 S17 T249	R9-Q13 PolarHBondContact O-N 3.47Å; K10-Q13 WeakPolarHBondContact O-CB 3.41Å; K10-Q13 PolarHBondContact O-N 3.23Å; Q13-K15 PolarHBondContact O-N 3.15Å; Q13-T16 WeakPolarHBondContact CA-OG1 3.31Å; Q13-T16 PolarHBondContact O-N 2.83Å; Q13-T16 PolarHBondContact O-OG1 2.9Å; Q13-S17 WeakPolarHBondContact O-CB 3.48Å; Q13-S17 PolarHBondContact O-N 3.47Å; Q13-S17 PolarHBondContact O-OG 2.98Å; Q13-S17 VanDerWaalsContact O-OG 3.08Å; Q13-T249 HydrophobicContact CB-CG2 4.21Å
14	E	58	Low	56.8	Low	109 Å²	109	69.2 Å²	69.2	51%	0.509	33%	0.332	S	S	.	.	H	α-helix	trans	-60.2	-43.3	176.9	-71.9	166.6	-178.4	0	0	111.9	K10 V12 H18	K10-E14 WeakPolarHBondContact CE-OE1 3.18Å; K10-E14 WeakPolarHBondContact O-CG 3.37Å; K10-E14 PolarHBondContact O-N 3.37Å; V12-E14 PolarHBondContact O-N 3.33Å; E14-H18 WeakPolarHBondContact O-CB 3.4Å; E14-H18 PolarHBondContact O-N 3.26Å
15	K	60.9	Low	56.7	Low	149 Å²	149	72.1 Å²	72.1	65%	0.648	35%	0.352	S	S	*	.	H	α-helix	trans	-67.3	-42.7	178.7	-76	-177.8	172.2	-171.9	0	112.9	R11 V12 Q13 H18 A19	R11-K15 WeakPolarHBondContact O-CG 3.34Å; R11-K15 PolarHBondContact O-N 2.82Å; R11-K15 VanDerWaalsContact O-N 3.1Å; V12-K15 PolarHBondContact O-N 3.5Å; Q13-K15 PolarHBondContact O-N 3.15Å; K15-H18 PolarHBondContact O-N 3.32Å; K15-A19 PolarHBondContact O-N 3.41Å
16	T	56.6	Low	56.5	Low	11 Å²	11	78 Å²	78	7%	0.067	37%	0.374	C	S	.	.	H	α-helix	trans	-66.5	-41.9	178.3	49.5	0	0	0	0	111.1	V12 Q13 H18 A19 Y20 I188 Y192 F250	V12-T16 HydrophobicContact CG1-CG2 4.46Å; V12-T16 PolarHBondContact O-N 2.83Å; V12-T16 PolarHBondContact O-OG1 3.32Å; V12-T16 VanDerWaalsContact O-OG1 3.09Å; Q13-T16 WeakPolarHBondContact CA-OG1 3.31Å; Q13-T16 PolarHBondContact O-N 2.83Å; Q13-T16 PolarHBondContact O-OG1 2.9Å; T16-H18 PolarHBondContact O-N 3.29Å; T16-A19 PolarHBondContact O-N 3.42Å; T16-Y20 WeakPolarHBondContact O-CB 3.47Å; T16-Y20 PolarHBondContact O-N 2.87Å; T16-I188 HydrophobicContact CG2-CD1 4.5Å; T16-Y192 HydrophobicContact CG2-CE1 4.36Å; T16-F250 HydrophobicContact CG2-CZ 4.28Å
17	S	54.5	Low	56	Low	37 Å²	37	74.2 Å²	74.2	26%	0.259	35%	0.354	S	S	.	.	H	α-helix	trans	-62.4	-41.1	173.6	-64.5	0	0	0	0	112.2	Q13 Y20 N21	Q13-S17 WeakPolarHBondContact O-CB 3.48Å; Q13-S17 PolarHBondContact O-N 3.47Å; Q13-S17 PolarHBondContact O-OG 2.98Å; Q13-S17 VanDerWaalsContact O-OG 3.08Å; S17-Y20 PolarHBondContact O-N 3.49Å; S17-N21 WeakPolarHBondContact O-CB 3.28Å; S17-N21 PolarHBondContact O-N 3.43Å; S17-N21 PolarHBondContact O-ND2 3.48Å
18	H	54.6	Low	55.5	Low	131 Å²	131	74 Å²	74	61%	0.606	35%	0.353	S	S	*	.	H	α-helix	trans	-63.9	-47	176.9	-176.8	74.3	0	0	0	112.4	E14 K15 T16 Y20 N21 H22	E14-H18 WeakPolarHBondContact O-CB 3.4Å; E14-H18 PolarHBondContact O-N 3.26Å; K15-H18 PolarHBondContact O-N 3.32Å; T16-H18 PolarHBondContact O-N 3.29Å; H18-Y20 VanDerWaalsContact C-N 3.33Å; H18-Y20 PolarHBondContact O-N 3.29Å; H18-N21 PolarHBondContact O-N 3.47Å; H18-H22 WeakPolarHBondContact O-CB 2.97Å; H18-H22 PolarHBondContact O-N 3.35Å
19	A	53.3	Low	55.2	Low	44 Å²	44	75.4 Å²	75.4	36%	0.364	37%	0.366	S	S	.	.	H	α-helix	trans	-61.8	-40.8	177.8	0	0	0	0	0	112.1	K15 T16 K23	K15-A19 PolarHBondContact O-N 3.41Å; T16-A19 PolarHBondContact O-N 3.42Å; A19-K23 WeakPolarHBondContact O-CG 3.32Å; A19-K23 PolarHBondContact O-N 3.22Å; A19-K23 VanDerWaalsContact O-N 3.13Å
20	Y	51.1	Low	54.6	Low	22 Å²	22	78.3 Å²	78.3	9%	0.086	38%	0.377	C	S	.	.	H	α-helix	trans	-61.8	-51.9	173.6	173.4	-107.4	0	0	0	111.8	T16 S17 H18 H22 K23 L24 L196 L197	T16-Y20 WeakPolarHBondContact O-CB 3.47Å; T16-Y20 PolarHBondContact O-N 2.87Å; S17-Y20 PolarHBondContact O-N 3.49Å; H18-Y20 VanDerWaalsContact C-N 3.33Å; H18-Y20 PolarHBondContact O-N 3.29Å; Y20-H22 VanDerWaalsContact C-N 3.3Å; Y20-H22 PolarHBondContact O-N 3.05Å; Y20-K23 PolarHBondContact O-N 3.27Å; Y20-K23 VanDerWaalsContact O-N 3.13Å; Y20-L24 HydrophobicContact CE1-CD2 4.16Å; Y20-L24 WeakPolarHBondContact O-CB 3.36Å; Y20-L24 PolarHBondContact O-N 3Å; Y20-L196 HydrophobicContact CD2-CB 3.53Å; Y20-L196 HydrophobicContact CD2-CD1 3.62Å; Y20-L196 HydrophobicContact CD2-CG 4.26Å; Y20-L196 HydrophobicContact CE2-CB 3.36Å; Y20-L196 HydrophobicContact CE2-CD1 4.15Å; Y20-L196 HydrophobicContact CE2-CG 4.41Å; Y20-L196 HydrophobicContact CG-CD1 3.98Å; Y20-L197 HydrophobicContact CE2-CD2 3.95Å; Y20-L197 HydrophobicContact CE2-CG 4.3Å
21	N	54.6	Low	54	Low	84 Å²	84	76.7 Å²	76.7	45%	0.449	37%	0.374	S	S	.	.	H	α-helix	trans	-60.3	-40	-179.5	-73.3	-20.9	0	0	0	112.1	S17 H18 L24 V25	S17-N21 WeakPolarHBondContact O-CB 3.28Å; S17-N21 PolarHBondContact O-N 3.43Å; S17-N21 PolarHBondContact O-ND2 3.48Å; H18-N21 PolarHBondContact O-N 3.47Å; N21-L24 PolarHBondContact O-N 3.49Å; N21-V25 VanDerWaalsContact O-CG2 3.32Å; N21-V25 WeakPolarHBondContact O-CG2 3.48Å; N21-V25 PolarHBondContact O-N 3.37Å
22	H	55.6	Low	53.2	Low	129 Å²	129	73.7 Å²	73.7	60%	0.597	38%	0.382	S	S	*	.	H	α-helix	trans	-61.9	-45	175.6	-173.1	-88.4	0	0	0	111.8	H18 Y20 W26	H18-H22 WeakPolarHBondContact O-CB 2.97Å; H18-H22 PolarHBondContact O-N 3.35Å; Y20-H22 VanDerWaalsContact C-N 3.3Å; Y20-H22 PolarHBondContact O-N 3.05Å; H22-W26 WeakPolarHBondContact O-CB 3.32Å; H22-W26 PolarHBondContact O-N 3.09Å
23	K	56.4	Low	52.2	Low	51 Å²	51	79.5 Å²	79.5	22%	0.222	41%	0.413	C	S	.	.	H	α-helix	trans	-67.6	-34.8	175.5	-70.1	-165.8	-170.5	-176	0	112.6	A19 Y20 W26 F27 N189 P193 L197	A19-K23 WeakPolarHBondContact O-CG 3.32Å; A19-K23 PolarHBondContact O-N 3.22Å; A19-K23 VanDerWaalsContact O-N 3.13Å; Y20-K23 PolarHBondContact O-N 3.27Å; Y20-K23 VanDerWaalsContact O-N 3.13Å; K23-W26 PolarHBondContact O-N 2.98Å; K23-F27 VanDerWaalsContact O-CB 3.25Å; K23-F27 WeakPolarHBondContact O-CB 3.46Å; K23-F27 PolarHBondContact O-N 2.92Å; K23-N189 PolarHBondContact NZ-O 3.44Å; K23-P193 HydrophobicContact CD-CB 3.95Å; K23-P193 HydrophobicContact CD-CG 3.84Å; K23-L197 HydrophobicContact CB-CD1 4.19Å
24	L	51	Low	51	Low	41 Å²	41	83.8 Å²	83.8	22%	0.215	43%	0.433	C	S	.	.	H	α-helix	trans	-65.9	-45.3	175.9	-177.2	66.9	0	0	0	111.8	Y20 N21 W26 F27 N28 L197 T200	Y20-L24 HydrophobicContact CE1-CD2 4.16Å; Y20-L24 WeakPolarHBondContact O-CB 3.36Å; Y20-L24 PolarHBondContact O-N 3Å; N21-L24 PolarHBondContact O-N 3.49Å; L24-W26 VanDerWaalsContact C-N 3.34Å; L24-F27 PolarHBondContact O-N 3.26Å; L24-N28 WeakPolarHBondContact O-CB 3.38Å; L24-N28 VanDerWaalsContact O-CG 3.24Å; L24-N28 PolarHBondContact O-N 3.36Å; L24-N28 PolarHBondContact O-ND2 2.9Å; L24-L197 HydrophobicContact CB-CD2 3.95Å; L24-L197 HydrophobicContact CD1-CD2 3.53Å; L24-L197 HydrophobicContact CG-CD2 4.36Å; L24-T200 HydrophobicContact CD1-CG2 4.35Å
25	V	53.3	Low	49.6	Very low	102 Å²	102	87.5 Å²	87.5	62%	0.618	45%	0.448	S	S	*	.	H	α-helix	trans	-59.9	-46.7	174	170	0	0	0	0	110.3	N21 F27 N28 S29	N21-V25 VanDerWaalsContact O-CG2 3.32Å; N21-V25 WeakPolarHBondContact O-CG2 3.48Å; N21-V25 PolarHBondContact O-N 3.37Å; V25-F27 PolarHBondContact O-N 3.21Å; V25-N28 PolarHBondContact O-N 3.19Å; V25-S29 WeakPolarHBondContact O-CB 3.38Å; V25-S29 PolarHBondContact O-N 2.92Å; V25-S29 PolarHBondContact O-OG 3.04Å
26	W	49.7	Very low	48	Very low	128 Å²	128	85.5 Å²	85.5	49%	0.485	45%	0.448	S	S	.	.	H	α-helix	trans	-60.3	-45.3	176.7	-177	89.7	0	0	0	112.1	H22 K23 L24 S29 R30	H22-W26 WeakPolarHBondContact O-CB 3.32Å; H22-W26 PolarHBondContact O-N 3.09Å; K23-W26 PolarHBondContact O-N 2.98Å; L24-W26 VanDerWaalsContact C-N 3.34Å; W26-S29 PolarHBondContact O-N 2.95Å; W26-S29 PolarHBondContact O-OG 3.28Å; W26-R30 VanDerWaalsContact CZ2-NE 3.27Å; W26-R30 VanDerWaalsContact CZ2-NH1 3.26Å; W26-R30 PolarHBondContact O-N 3.11Å
27	F	50.2	Low	46.6	Very low	14 Å²	14	90 Å²	90	6%	0.061	47%	0.47	C	S	.	.	H	α-helix	trans	-63.4	-45.3	177	-177.5	-104.4	0	0	0	112.3	K23 L24 V25 S29 R30 L31 I128 V132 L197	K23-F27 VanDerWaalsContact O-CB 3.25Å; K23-F27 WeakPolarHBondContact O-CB 3.46Å; K23-F27 PolarHBondContact O-N 2.92Å; L24-F27 PolarHBondContact O-N 3.26Å; V25-F27 PolarHBondContact O-N 3.21Å; F27-S29 PolarHBondContact O-N 2.92Å; F27-R30 CarbonylContact O-C 3.6Å; F27-R30 PolarHBondContact O-N 3.37Å; F27-R30 VanDerWaalsContact O-N 3.15Å; F27-L31 HydrophobicContact CD1-CD1 3.79Å; F27-L31 HydrophobicContact CD1-CG 4.24Å; F27-L31 HydrophobicContact CE1-CD1 3.3Å; F27-L31 HydrophobicContact CE1-CD2 4.42Å; F27-L31 HydrophobicContact CE1-CG 3.87Å; F27-L31 HydrophobicContact CZ-CD1 3.9Å; F27-L31 HydrophobicContact CZ-CD2 4.2Å; F27-L31 HydrophobicContact CZ-CG 4.06Å; F27-L31 PolarHBondContact O-N 3.27Å; F27-I128 HydrophobicContact CD2-CD1 4.32Å; F27-I128 HydrophobicContact CE2-CD1 4.17Å; F27-I128 HydrophobicContact CE2-CG1 4.05Å; F27-V132 HydrophobicContact CE1-CG1 4.23Å; F27-V132 HydrophobicContact CE1-CG2 4.45Å; F27-V132 HydrophobicContact CZ-CB 4.25Å; F27-V132 HydrophobicContact CZ-CG1 4.17Å; F27-V132 HydrophobicContact CZ-CG2 3.93Å; F27-L197 HydrophobicContact CB-CD1 4.33Å
28	N	53	Low	45.2	Very low	83 Å²	83	93.9 Å²	93.9	44%	0.444	49%	0.488	S	S	.	.	H	α-helix	trans	-65.6	-37.5	178.1	-72.3	-20.6	0	0	0	112.1	L24 V25 R30 L31 G32	L24-N28 WeakPolarHBondContact O-CB 3.38Å; L24-N28 VanDerWaalsContact O-CG 3.24Å; L24-N28 PolarHBondContact O-N 3.36Å; L24-N28 PolarHBondContact O-ND2 2.9Å; V25-N28 PolarHBondContact O-N 3.19Å; N28-R30 PolarHBondContact O-N 3.24Å; N28-L31 PolarHBondContact O-N 3.46Å; N28-G32 PolarHBondContact O-N 2.72Å; N28-G32 VanDerWaalsContact O-N 3.1Å
29	S	51.3	Low	44	Very low	66 Å²	66	96.2 Å²	96.2	46%	0.462	50%	0.496	S	S	.	.	H	α-helix	trans	-62.6	-31.4	174.4	75.4	0	0	0	0	112.4	V25 W26 F27	V25-S29 WeakPolarHBondContact O-CB 3.38Å; V25-S29 PolarHBondContact O-N 2.92Å; V25-S29 PolarHBondContact O-OG 3.04Å; W26-S29 PolarHBondContact O-N 2.95Å; W26-S29 PolarHBondContact O-OG 3.28Å; F27-S29 PolarHBondContact O-N 2.92Å
30	R	49.1	Very low	42.7	Very low	101 Å²	101	99.4 Å²	99.4	38%	0.381	52%	0.516	S	S	.	.	H	α-helix	trans	-81.1	-34	174	-77.4	-174.5	168.1	-161.2	-1.4	113.4	W26 F27 N28 G32 N33	W26-R30 VanDerWaalsContact CZ2-NE 3.27Å; W26-R30 VanDerWaalsContact CZ2-NH1 3.26Å; W26-R30 PolarHBondContact O-N 3.11Å; F27-R30 CarbonylContact O-C 3.6Å; F27-R30 PolarHBondContact O-N 3.37Å; F27-R30 VanDerWaalsContact O-N 3.15Å; N28-R30 PolarHBondContact O-N 3.24Å; R30-G32 PolarHBondContact O-N 3.33Å; R30-N33 CarbonylContact O-C 3.37Å; R30-N33 PolarHBondContact O-N 2.87Å
31	L	48.9	Very low	41.7	Very low	91 Å²	91	103.8 Å²	103.8	48%	0.476	55%	0.547	S	S	.	.	H	α-helix	trans	-63.6	-30.8	172.1	-77.3	178	0	0	0	112.4	F27 N28 N33	F27-L31 HydrophobicContact CD1-CD1 3.79Å; F27-L31 HydrophobicContact CD1-CG 4.24Å; F27-L31 HydrophobicContact CE1-CD1 3.3Å; F27-L31 HydrophobicContact CE1-CD2 4.42Å; F27-L31 HydrophobicContact CE1-CG 3.87Å; F27-L31 HydrophobicContact CZ-CD1 3.9Å; F27-L31 HydrophobicContact CZ-CD2 4.2Å; F27-L31 HydrophobicContact CZ-CG 4.06Å; F27-L31 PolarHBondContact O-N 3.27Å; N28-L31 PolarHBondContact O-N 3.46Å; L31-N33 VanDerWaalsContact C-N 3.25Å; L31-N33 PolarHBondContact O-N 3.27Å
32	G	41.4	Very low	40.5	Very low	62 Å²	62	106.9 Å²	106.9	64%	0.639	56%	0.562	S	S	*	*	T	Hydrogen-bonded Turn	trans	-69.9	-20	172.2	0	0	0	0	0	114.1	N28 R30	N28-G32 PolarHBondContact O-N 2.72Å; N28-G32 VanDerWaalsContact O-N 3.1Å; R30-G32 PolarHBondContact O-N 3.33Å
33	N	35.1	Very low	39	Very low	125 Å²	125	108.9 Å²	108.9	67%	0.668	57%	0.572	S	S	*	*	S	Bend	trans	-113.6	97.8	-178.6	-74.4	-14.5	0	0	0	109.8	R30 L31 F35	R30-N33 CarbonylContact O-C 3.37Å; R30-N33 PolarHBondContact O-N 2.87Å; L31-N33 VanDerWaalsContact C-N 3.25Å; L31-N33 PolarHBondContact O-N 3.27Å; N33-F35 PolarHBondContact O-N 3.41Å
34	Q	32.3	Very low	37.7	Very low	180 Å²	180	113.9 Å²	113.9	84%	0.841	60%	0.596	S	S	*	*			trans	-42	128.6	164.5	-84	-178.6	-11	0	0	111.5
35	F	28.1	Very low	36.6	Very low	186 Å²	186	121.4 Å²	121.4	82%	0.816	63%	0.627	S	S	*	*	S	Bend	trans	78.2	139.7	164.5	-78	-92.6	0	0	0	120.5	N33	N33-F35 PolarHBondContact O-N 3.41Å
36	T	27.9	Very low	35.6	Very low	107 Å²	107	120.3 Å²	120.3	66%	0.656	62%	0.624	S	S	*	*			trans	85.1	92.1	166.4	66.8	0	0	0	0	118.1	N38	T36-N38 PolarHBondContact O-N 3.27Å
37	M	27	Very low	34.8	Very low	105 Å²	105	122.1 Å²	122.1	52%	0.517	64%	0.643	S	S	.	*			trans	-63.7	85.4	152.3	-90.2	-154.2	159.7	0	0	109.4	K39 D127	M37-K39 PolarHBondContact O-N 3.46Å; M37-D127 HydrophobicContact CE-CB 3.92Å; M37-D127 HydrophobicContact SD-CB 3.85Å
38	N	26	Very low	33.9	Very low	119 Å²	119	129.5 Å²	129.5	64%	0.636	68%	0.677	S	S	*	*			trans	-82.9	110	163.5	-98.5	-23.9	0	0	0	109.9	T36	T36-N38 PolarHBondContact O-N 3.27Å
39	K	28.2	Very low	33	Very low	181 Å²	181	126.9 Å²	126.9	79%	0.787	67%	0.666	S	S	*	*			trans	0.9	117.9	144.6	-63	173.9	178.3	179.2	0	115.5	M37	M37-K39 PolarHBondContact O-N 3.46Å
40	S	26.1	Very low	32.3	Very low	111 Å²	111	130.1 Å²	130.1	78%	0.776	68%	0.683	S	S	*	*				-168.6	98.4	129.8	-81.9	0	0	0	0	106.3	I42	S40-I42 PolarHBondContact O-N 3.45Å
41	P	29.9	Very low	31.5	Very low	113 Å²	113	127 Å²	127	73%	0.734	68%	0.675	S	S	*	*			trans	-56.9	134.6	159.3	17.3	-14.6	0	0	0	106.3	E43	P41-E43 VanDerWaalsContact C-N 3.29Å; P41-E43 PolarHBondContact O-N 2.97Å
42	I	29.2	Very low	30.9	Very low	150 Å²	150	126 Å²	126	77%	0.769	67%	0.668	S	S	*	*			trans	-55.6	105	166.5	-69	162.2	0	0	0	104.7	S40 E44	S40-I42 PolarHBondContact O-N 3.45Å; I42-E44 HydrophobicContact CG2-CB 4.45Å; I42-E44 HydrophobicContact CG2-CG 4.05Å; I42-E44 PolarHBondContact O-N 2.89Å
43	E	25.2	Very low	30.5	Very low	171 Å²	171	130.9 Å²	130.9	80%	0.799	68%	0.679	S	S	*	*			trans	-66.6	66.4	167.3	-72.1	-176.4	171.5	0	0	107.7	P41 K45	P41-E43 VanDerWaalsContact C-N 3.29Å; P41-E43 PolarHBondContact O-N 2.97Å; E43-K45 VanDerWaalsContact C-N 3.31Å; E43-K45 PolarHBondContact O-N 3.26Å; E43-K45 VanDerWaalsContact O-N 3.14Å
44	E	28.2	Very low	30.5	Very low	155 Å²	155	131.9 Å²	131.9	72%	0.724	68%	0.68	S	S	*	*			trans	-67.8	106.8	149	-90.1	-173.2	171.8	0	0	104.5	I42 S46	I42-E44 HydrophobicContact CG2-CB 4.45Å; I42-E44 HydrophobicContact CG2-CG 4.05Å; I42-E44 PolarHBondContact O-N 2.89Å; E44-S46 PolarHBondContact O-N 2.85Å
45	K	27.8	Very low	30.9	Very low	199 Å²	199	124.8 Å²	124.8	87%	0.865	65%	0.645	S	S	*	*			trans	-61.2	62.9	162.6	-68.2	177.8	176.8	177	0	109	E43	E43-K45 VanDerWaalsContact C-N 3.31Å; E43-K45 PolarHBondContact O-N 3.26Å; E43-K45 VanDerWaalsContact O-N 3.14Å
46	S	32.4	Very low	31.3	Very low	80 Å²	80	119.8 Å²	119.8	56%	0.559	62%	0.621	S	S	*	*			trans	-76.9	121.2	160.2	58.2	0	0	0	0	105.5	E44 E48	E44-S46 PolarHBondContact O-N 2.85Å; S46-E48 VanDerWaalsContact C-N 3.31Å; S46-E48 PolarHBondContact O-N 2.99Å
47	N	32.9	Very low	32.1	Very low	166 Å²	166	117.2 Å²	117.2	89%	0.888	61%	0.608	S	S	*	*			trans	-47.7	103.4	164.2	-68.8	-26.1	0	0	0	107	S49	N47-S49 PolarHBondContact O-N 3.2Å
48	E	31.8	Very low	32.6	Very low	168 Å²	168	113.1 Å²	113.1	79%	0.785	59%	0.589	S	S	*	*			trans	-56.6	114.5	-173.5	-75.9	177.8	156	0	0	107.7	S46 T50	S46-E48 VanDerWaalsContact C-N 3.31Å; S46-E48 PolarHBondContact O-N 2.99Å; E48-T50 PolarHBondContact O-N 3.39Å; E48-T50 VanDerWaalsContact O-N 3.16Å
49	S	35.2	Very low	33.3	Very low	28 Å²	28	111 Å²	111	20%	0.196	58%	0.577	C	S	.	*			trans	-58.3	124.5	168.1	82.1	0	0	0	0	106.3	N47 V51 H52	N47-S49 PolarHBondContact O-N 3.2Å; S49-V51 PolarHBondContact O-N 2.95Å; S49-V51 WeakPolarHBondContact OG-CB 3.44Å; S49-H52 PolarHBondContact O-CD2 3.46Å; S49-H52 PolarHBondContact O-N 2.99Å; S49-H52 PolarHBondContact OG-NE2 2.97Å; S49-H52 VanDerWaalsContact OG-NE2 3.14Å
50	T	34.8	Very low	33.9	Very low	135 Å²	135	105.4 Å²	105.4	83%	0.828	56%	0.556	S	S	*	*	G	3₁₀ helix	trans	-58.7	-4.6	178	38.9	0	0	0	0	113.3	E48 H52	E48-T50 PolarHBondContact O-N 3.39Å; E48-T50 VanDerWaalsContact O-N 3.16Å; T50-H52 VanDerWaalsContact C-N 3.26Å; T50-H52 PolarHBondContact O-N 3.26Å
51	V	34.1	Very low	34.6	Very low	35 Å²	35	100.5 Å²	100.5	21%	0.212	52%	0.521	C	S	.	.	G	3₁₀ helix	trans	-61.8	-29.6	174.9	178.1	0	0	0	0	112.6	S49 N53 P167	S49-V51 PolarHBondContact O-N 2.95Å; S49-V51 WeakPolarHBondContact OG-CB 3.44Å; V51-N53 PolarHBondContact O-N 2.76Å; V51-P167 HydrophobicContact CB-CB 4.29Å; V51-P167 HydrophobicContact CG1-CB 3.25Å; V51-P167 HydrophobicContact CG1-CG 3.14Å; V51-P167 HydrophobicContact CG2-CB 4.06Å
52	H	36.2	Very low	35.2	Very low	71 Å²	71	96.4 Å²	96.4	33%	0.329	49%	0.493	S	S	.	.	G	3₁₀ helix	trans	-74.7	-21.5	-166.6	-63.3	-42.3	0	0	0	115.7	S49 T50 Q54 Y55	S49-H52 PolarHBondContact O-CD2 3.46Å; S49-H52 PolarHBondContact O-N 2.99Å; S49-H52 PolarHBondContact OG-NE2 2.97Å; S49-H52 VanDerWaalsContact OG-NE2 3.14Å; T50-H52 VanDerWaalsContact C-N 3.26Å; T50-H52 PolarHBondContact O-N 3.26Å; H52-Q54 VanDerWaalsContact C-N 3.31Å; H52-Q54 PolarHBondContact O-N 2.95Å; H52-Y55 HydrophobicContact CB-CE2 4.26Å; H52-Y55 AromaticContact ND1-CE2 3.93Å; H52-Y55 PolarHBondContact ND1-OH 2.94Å; H52-Y55 WeakPolarHBondContact O-CD2 3.49Å; H52-Y55 WeakPolarHBondContact O-CE2 3.45Å
53	N	31.9	Very low	35.6	Very low	163 Å²	163	89.9 Å²	89.9	87%	0.872	46%	0.461	S	S	*	.	G	3₁₀ helix	trans	-85.7	4.1	-179.3	-78.2	-16.9	0	0	0	114.4	V51	V51-N53 PolarHBondContact O-N 2.76Å
54	Q	36.1	Very low	36.1	Very low	146 Å²	146	83 Å²	83	68%	0.682	43%	0.431	S	S	*	.	G	3₁₀ helix	trans	-104.8	23.3	-177.5	-69.8	-173	-9.6	0	0	114.2	H52	H52-Q54 VanDerWaalsContact C-N 3.31Å; H52-Q54 PolarHBondContact O-N 2.95Å
55	Y	39.5	Very low	36.4	Very low	31 Å²	31	81.4 Å²	81.4	12%	0.122	42%	0.423	C	S	.	.	P	Polyproline II helix	trans	-87.2	133.8	179.2	-61.6	-51.8	0	0	0	112.3	H52 L121 T163	H52-Y55 HydrophobicContact CB-CE2 4.26Å; H52-Y55 AromaticContact ND1-CE2 3.93Å; H52-Y55 PolarHBondContact ND1-OH 2.94Å; H52-Y55 WeakPolarHBondContact O-CD2 3.49Å; H52-Y55 WeakPolarHBondContact O-CE2 3.45Å; Y55-L121 HydrophobicContact CD1-CD2 3.9Å; Y55-L121 HydrophobicContact CD2-CB 4.04Å; Y55-L121 HydrophobicContact CE1-CD2 3.96Å; Y55-L121 HydrophobicContact CE2-CB 4.4Å; Y55-L121 HydrophobicContact CG-CB 4.24Å; Y55-L121 HydrophobicContact CG-CD1 4.32Å; Y55-L121 HydrophobicContact CG-CD2 4.2Å; Y55-L121 HydrophobicContact CG-CG 4.49Å; Y55-T163 HydrophobicContact CD1-CG2 3.44Å; Y55-T163 VanDerWaalsContact CD1-CG2 3.44Å; Y55-T163 HydrophobicContact CE1-CG2 4.02Å; Y55-T163 HydrophobicContact CG-CG2 4.42Å
56	W	36.6	Very low	36.7	Very low	82 Å²	82	73.5 Å²	73.5	31%	0.311	39%	0.393	S	S	.	.	P	Polyproline II helix	trans	-59.4	160.7	178.7	-73.3	32.9	0	0	0	111.4	D60 L61 W75 K123	W56-D60 HydrophobicContact CB-CB 4.23Å; W56-D60 HydrophobicContact CD2-CB 4.2Å; W56-D60 HydrophobicContact CE3-CB 3.32Å; W56-D60 HydrophobicContact CZ3-CB 3.92Å; W56-L61 HydrophobicContact CB-CD2 4.22Å; W56-L61 HydrophobicContact CB-CG 4.1Å; W56-W75 HydrophobicContact CH2-CE3 4.2Å; W56-W75 AromaticContact CH2-CH2 3.49Å; W56-W75 HydrophobicContact CH2-CH2 3.49Å; W56-W75 VanDerWaalsContact CH2-CH2 3.49Å; W56-W75 AromaticContact CH2-CZ3 3.3Å; W56-W75 HydrophobicContact CH2-CZ3 3.3Å; W56-W75 AromaticContact CZ2-CH2 3.73Å; W56-W75 HydrophobicContact CZ2-CH2 3.73Å; W56-W75 HydrophobicContact CZ2-CZ3 4.04Å; W56-W75 HydrophobicContact CZ3-CH2 4.12Å; W56-W75 AromaticContact CZ3-CZ3 3.61Å; W56-W75 HydrophobicContact CZ3-CZ3 3.61Å; W56-K123 PolarHBondContact O-NZ 3.37Å
57	S	44.4	Very low	36.8	Very low	53 Å²	53	76.2 Å²	76.2	37%	0.371	40%	0.401	S	S	.	.	P	Polyproline II helix	trans	-64	153.2	168.4	84.6	0	0	0	0	109	N59 D60 L61	S57-N59 PolarHBondContact O-N 2.95Å; S57-D60 VanDerWaalsContact CB-OD2 3.29Å; S57-D60 WeakPolarHBondContact CB-OD2 3.22Å; S57-D60 PolarHBondContact N-OD2 3.24Å; S57-D60 PolarHBondContact O-N 3.1Å; S57-D60 VanDerWaalsContact O-N 3.14Å; S57-D60 PolarHBondContact OG-N 3.36Å; S57-D60 PolarHBondContact OG-OD2 3.45Å; S57-L61 PolarHBondContact O-N 3.44Å
58	T	38.9	Very low	37.1	Very low	19 Å²	19	72.4 Å²	72.4	12%	0.117	39%	0.388	C	S	.	.	H	α-helix	trans	-60.6	-32.3	-178.9	-43.2	0	0	0	0	111.7	L61 L62 N114 I117	T58-L61 PolarHBondContact O-N 3.09Å; T58-L62 HydrophobicContact CG2-CD1 4.2Å; T58-L62 WeakPolarHBondContact O-CD1 3.31Å; T58-L62 VanDerWaalsContact O-CG 3.28Å; T58-L62 WeakPolarHBondContact O-CG 3.36Å; T58-L62 PolarHBondContact O-N 2.84Å; T58-N114 HydrophobicContact CG2-CB 4.26Å; T58-N114 WeakPolarHBondContact CG2-OD1 3.49Å; T58-I117 HydrophobicContact CG2-CB 4.02Å; T58-I117 HydrophobicContact CG2-CD1 3.4Å; T58-I117 VanDerWaalsContact CG2-CD1 3.4Å; T58-I117 HydrophobicContact CG2-CG1 4.28Å; T58-I117 HydrophobicContact CG2-CG2 3.94Å
59	N	39.6	Very low	37.6	Very low	75 Å²	75	71.7 Å²	71.7	40%	0.401	39%	0.389	S	S	.	.	H	α-helix	trans	-64.9	-44.5	176.2	-68.3	-3.2	0	0	0	111.6	S57 L61 L62 S63 Y83	S57-N59 PolarHBondContact O-N 2.95Å; N59-L61 PolarHBondContact O-N 3.31Å; N59-L62 PolarHBondContact O-N 3.44Å; N59-S63 PolarHBondContact O-N 3.25Å; N59-S63 PolarHBondContact O-OG 2.9Å; N59-Y83 HydrophobicContact CB-CE2 4.06Å
60	D	41.3	Very low	37.6	Very low	62 Å²	62	75.7 Å²	75.7	33%	0.332	41%	0.408	S	S	.	.	H	α-helix	trans	-66.5	-28.2	-179.5	-50.4	-48.6	0	0	0	112.2	W56 S57 L62 S63 C64	W56-D60 HydrophobicContact CB-CB 4.23Å; W56-D60 HydrophobicContact CD2-CB 4.2Å; W56-D60 HydrophobicContact CE3-CB 3.32Å; W56-D60 HydrophobicContact CZ3-CB 3.92Å; S57-D60 VanDerWaalsContact CB-OD2 3.29Å; S57-D60 WeakPolarHBondContact CB-OD2 3.22Å; S57-D60 PolarHBondContact N-OD2 3.24Å; S57-D60 PolarHBondContact O-N 3.1Å; S57-D60 VanDerWaalsContact O-N 3.14Å; S57-D60 PolarHBondContact OG-N 3.36Å; S57-D60 PolarHBondContact OG-OD2 3.45Å; D60-L62 VanDerWaalsContact C-N 3.28Å; D60-S63 WeakPolarHBondContact CA-OG 3.49Å; D60-S63 PolarHBondContact O-OG 3.22Å; D60-C64 PolarHBondContact O-SG 3.47Å
61	L	40.2	Very low	38.1	Very low	8 Å²	8	75.7 Å²	75.7	4%	0.042	40%	0.403	C	S	.	.	H	α-helix	trans	-71.3	-25.4	174.6	-69.5	169.9	0	0	0	112.7	W56 S57 T58 N59 I117 L121 N159 T163	W56-L61 HydrophobicContact CB-CD2 4.22Å; W56-L61 HydrophobicContact CB-CG 4.1Å; S57-L61 PolarHBondContact O-N 3.44Å; T58-L61 PolarHBondContact O-N 3.09Å; N59-L61 PolarHBondContact O-N 3.31Å; L61-I117 HydrophobicContact CD1-CG2 3.67Å; L61-L121 HydrophobicContact CD1-CD1 3.75Å; L61-N159 PolarHBondContact O-ND2 3.29Å; L61-T163 HydrophobicContact CD2-CG2 4.24Å; L61-T163 WeakPolarHBondContact CD2-OG1 3.3Å
62	L	43.7	Very low	38.3	Very low	28 Å²	28	80.7 Å²	80.7	15%	0.147	43%	0.429	C	S	.	.	H	α-helix	trans	-100.1	-33.4	-173.4	-67.8	169.1	0	0	0	112.7	T58 N59 D60 C64 Y83 Q113 I117	T58-L62 HydrophobicContact CG2-CD1 4.2Å; T58-L62 WeakPolarHBondContact O-CD1 3.31Å; T58-L62 VanDerWaalsContact O-CG 3.28Å; T58-L62 WeakPolarHBondContact O-CG 3.36Å; T58-L62 PolarHBondContact O-N 2.84Å; N59-L62 PolarHBondContact O-N 3.44Å; D60-L62 VanDerWaalsContact C-N 3.28Å; L62-C64 PolarHBondContact O-N 2.96Å; L62-Y83 WeakPolarHBondContact CB-OH 3.36Å; L62-Y83 WeakPolarHBondContact CD1-OH 3.47Å; L62-Q113 HydrophobicContact CD1-CG 4.28Å; L62-I117 HydrophobicContact CD1-CD1 4.32Å; L62-I117 HydrophobicContact CD2-CD1 4.11Å; L62-I117 HydrophobicContact CG-CD1 4.22Å
63	S	37.7	Very low	38.4	Very low	13 Å²	13	80.6 Å²	80.6	9%	0.091	43%	0.428	C	S	.	.	S	Bend	trans	-67.5	-7.7	172.2	53.8	0	0	0	0	113.8	N59 D60 E65 T81	N59-S63 PolarHBondContact O-N 3.25Å; N59-S63 PolarHBondContact O-OG 2.9Å; D60-S63 WeakPolarHBondContact CA-OG 3.49Å; D60-S63 PolarHBondContact O-OG 3.22Å; S63-E65 PolarHBondContact O-N 3.11Å; S63-T81 WeakPolarHBondContact CB-OG1 3.24Å
64	C	36	Very low	38.4	Very low	26 Å²	26	82.1 Å²	82.1	18%	0.176	43%	0.427	C	S	.	.	B	Isolated β-bridge	trans	-74.6	91.9	172.4	-73.4	0	0	0	0	111.2	D60 L62 C66	D60-C64 PolarHBondContact O-SG 3.47Å; L62-C64 PolarHBondContact O-N 2.96Å; C64-C66 PolarHBondContact O-N 3.36Å
65	E	34.4	Very low	38.1	Very low	122 Å²	122	81.5 Å²	81.5	57%	0.57	42%	0.419	S	S	*	.			trans	-77.7	102.2	161.5	-68.4	-171.7	158.3	0	0	109.3	S63	S63-E65 PolarHBondContact O-N 3.11Å
66	C	33.5	Very low	37.8	Very low	32 Å²	32	86.5 Å²	86.5	22%	0.216	45%	0.447	C	S	.	.			trans	-82.2	118.7	169.6	-66.3	0	0	0	0	109.5	C64 S68	C64-C66 PolarHBondContact O-N 3.36Å; C66-S68 PolarHBondContact O-N 3.28Å; C66-S68 VanDerWaalsContact O-N 3.14Å
67	D	34.1	Very low	37.4	Very low	137 Å²	137	88.6 Å²	88.6	73%	0.733	46%	0.46	S	S	*	.			trans	-59.9	115.6	166.8	-146.4	-5.7	0	0	0	108.3	N69	D67-N69 PolarHBondContact O-N 3.39Å
68	S	40.3	Very low	37	Very low	87 Å²	87	87.2 Å²	87.2	61%	0.608	45%	0.45	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.1	0.2	-154.4	58	0	0	0	0	116.2	C66	C66-S68 PolarHBondContact O-N 3.28Å; C66-S68 VanDerWaalsContact O-N 3.14Å
69	N	42	Very low	36.9	Very low	152 Å²	152	93.8 Å²	93.8	81%	0.813	48%	0.484	S	S	*	.	T	Hydrogen-bonded Turn	trans	-128.9	7.8	-166.8	-78.3	-24.2	0	0	0	116.9	D67	D67-N69 PolarHBondContact O-N 3.39Å
70	N	34.7	Very low	36.7	Very low	113 Å²	113	98.4 Å²	98.4	60%	0.604	50%	0.504	S	S	*	.			trans	-121	127.2	-179.9	-116.7	-12.7	0	0	0	112.9	D72 E73	N70-D72 PolarHBondContact O-N 3.4Å; N70-E73 WeakPolarHBondContact O-CG 3.5Å
71	D	44.1	Very low	36.3	Very low	134 Å²	134	97.8 Å²	97.8	72%	0.717	50%	0.502	S	S	*	.	S	Bend	trans	-73.6	-15.2	174.8	-77.4	-46.4	0	0	0	112.3	E73 R222	D71-E73 PolarHBondContact O-N 3.11Å; D71-R222 IonicContact OD1-NH1 3.56Å
72	D	39.3	Very low	35.8	Very low	141 Å²	141	104.8 Å²	104.8	75%	0.754	54%	0.535	S	S	*	.	S	Bend	trans	-95	47.7	179.2	-69.6	-32.2	0	0	0	112.7	N70 K74	N70-D72 PolarHBondContact O-N 3.4Å; D72-K74 PolarHBondContact O-N 2.94Å
73	E	39	Very low	35.3	Very low	69 Å²	69	107.1 Å²	107.1	32%	0.322	54%	0.542	S	S	.	.			trans	-55.4	96.1	-168.2	-65.4	174.5	142.6	0	0	113.4	N70 D71 R158 R162	N70-E73 WeakPolarHBondContact O-CG 3.5Å; D71-E73 PolarHBondContact O-N 3.11Å; E73-R158 IonicContact OE1-NH2 3.57Å; E73-R162 VanDerWaalsContact CD-NH1 3.31Å; E73-R162 IonicContact OE1-NH1 3.3Å; E73-R162 PolarHBondContact OE1-NH1 3.24Å; E73-R162 IonicContact OE2-CZ 2.6Å; E73-R162 IonicContact OE2-NH1 2.65Å; E73-R162 PolarHBondContact OE2-NH1 3.34Å; E73-R162 IonicContact OE2-NH2 3.21Å; E73-R162 PolarHBondContact OE2-NH2 2.98Å
74	K	30.7	Very low	35	Very low	194 Å²	194	114.5 Å²	114.5	84%	0.843	58%	0.575	S	S	*	*			trans	-74	132.2	162.4	-77.9	-177.3	178.1	177.2	0	109.1	D72 L76	D72-K74 PolarHBondContact O-N 2.94Å; K74-L76 PolarHBondContact O-N 3.36Å
75	W	31	Very low	34.7	Very low	134 Å²	134	125 Å²	125	51%	0.508	61%	0.611	S	S	.	*			trans	-71.3	118	179.6	-62.9	79.8	0	0	0	110.5	W56	W56-W75 HydrophobicContact CH2-CE3 4.2Å; W56-W75 AromaticContact CH2-CH2 3.49Å; W56-W75 HydrophobicContact CH2-CH2 3.49Å; W56-W75 VanDerWaalsContact CH2-CH2 3.49Å; W56-W75 AromaticContact CH2-CZ3 3.3Å; W56-W75 HydrophobicContact CH2-CZ3 3.3Å; W56-W75 AromaticContact CZ2-CH2 3.73Å; W56-W75 HydrophobicContact CZ2-CH2 3.73Å; W56-W75 HydrophobicContact CZ2-CZ3 4.04Å; W56-W75 HydrophobicContact CZ3-CH2 4.12Å; W56-W75 AromaticContact CZ3-CZ3 3.61Å; W56-W75 HydrophobicContact CZ3-CZ3 3.61Å
76	L	32.5	Very low	34.5	Very low	136 Å²	136	121 Å²	121	71%	0.712	60%	0.599	S	S	*	*			trans	-106.6	109.6	162.5	-67.7	169.2	0	0	0	106.4	K74 S78	K74-L76 PolarHBondContact O-N 3.36Å; L76-S78 PolarHBondContact O-N 3.35Å
77	H	28.6	Very low	34.2	Very low	126 Å²	126	125.9 Å²	125.9	58%	0.583	62%	0.623	S	S	*	*	B	Isolated β-bridge	trans	-65.4	115.6	159.3	-75	-66.8	0	0	0	105.9	N79	H77-N79 PolarHBondContact O-N 2.9Å
78	S	34.9	Very low	33.9	Very low	24 Å²	24	124.4 Å²	124.4	17%	0.168	61%	0.614	C	S	.	*			trans	-67.7	121.6	168.8	110.4	0	0	0	0	106.6	L76 E80 T81	L76-S78 PolarHBondContact O-N 3.35Å; S78-E80 PolarHBondContact O-N 2.92Å; S78-E80 PolarHBondContact OG-N 3.22Å; S78-T81 PolarHBondContact O-OG1 3.08Å; S78-T81 PolarHBondContact OG-N 3.44Å; S78-T81 PolarHBondContact OG-OG1 3.32Å; S78-T81 VanDerWaalsContact OG-OG1 3.1Å
79	N	36.9	Very low	33.3	Very low	156 Å²	156	127.6 Å²	127.6	83%	0.834	63%	0.625	S	S	*	*	T	Hydrogen-bonded Turn	trans	-68.9	-6.7	169.6	-76.1	-10.7	0	0	0	111.4	H77	H77-N79 PolarHBondContact O-N 2.9Å
80	E	35.4	Very low	32.9	Very low	173 Å²	173	125.3 Å²	125.3	81%	0.808	61%	0.612	S	S	*	*	T	Hydrogen-bonded Turn	trans	-90.3	-5.2	-175.2	-65.2	-170.9	166.1	0	0	113.8	S78 E82	S78-E80 PolarHBondContact O-N 2.92Å; S78-E80 PolarHBondContact OG-N 3.22Å; E80-E82 PolarHBondContact O-N 3.12Å
81	T	33.4	Very low	32.9	Very low	49 Å²	49	127.6 Å²	127.6	30%	0.301	61%	0.613	S	S	.	*			trans	-90.4	44.3	173.1	33.9	0	0	0	0	112.5	S63 S78 Y83	S63-T81 WeakPolarHBondContact CB-OG1 3.24Å; S78-T81 PolarHBondContact O-OG1 3.08Å; S78-T81 PolarHBondContact OG-N 3.44Å; S78-T81 PolarHBondContact OG-OG1 3.32Å; S78-T81 VanDerWaalsContact OG-OG1 3.1Å; T81-Y83 PolarHBondContact O-N 3.37Å
82	E	29.9	Very low	32.3	Very low	155 Å²	155	127.1 Å²	127.1	72%	0.724	61%	0.609	S	S	*	*			trans	-74.3	98.5	156.6	-100	-175	162.2	0	0	108.1	E80 H84	E80-E82 PolarHBondContact O-N 3.12Å; E82-H84 PolarHBondContact O-N 3.36Å
83	Y	33.7	Very low	32	Very low	77 Å²	77	121.3 Å²	121.3	30%	0.302	58%	0.583	S	S	.	*			trans	-60.1	95.6	176.5	-81.4	-96.4	0	0	0	110.7	N59 L62 T81 R85 L110	N59-Y83 HydrophobicContact CB-CE2 4.06Å; L62-Y83 WeakPolarHBondContact CB-OH 3.36Å; L62-Y83 WeakPolarHBondContact CD1-OH 3.47Å; T81-Y83 PolarHBondContact O-N 3.37Å; Y83-R85 PolarHBondContact O-N 2.99Å; Y83-R85 VanDerWaalsContact O-N 3.14Å; Y83-L110 HydrophobicContact CD1-CD1 4.25Å; Y83-L110 HydrophobicContact CE1-CD1 4.16Å; Y83-L110 HydrophobicContact CE1-CD2 4.05Å
84	H	30.6	Very low	31.7	Very low	167 Å²	167	119.8 Å²	119.8	77%	0.773	58%	0.578	S	S	*	*			trans	-66.5	111	159.5	-65.5	-56.5	0	0	0	107.3	E82 A86	E82-H84 PolarHBondContact O-N 3.36Å; H84-A86 VanDerWaalsContact C-N 3.3Å; H84-A86 PolarHBondContact O-N 3.2Å
85	R	30.2	Very low	31.7	Very low	246 Å²	246	116.2 Å²	116.2	93%	0.928	57%	0.569	S	S	*	*			trans	-53.5	101.2	164.3	-79.8	-179	179.2	167.4	-0	106.6	Y83 N87	Y83-R85 PolarHBondContact O-N 2.99Å; Y83-R85 VanDerWaalsContact O-N 3.14Å; R85-N87 PolarHBondContact O-N 2.92Å
86	A	30.5	Very low	31.8	Very low	39 Å²	39	116.4 Å²	116.4	32%	0.322	57%	0.573	S	S	.	*			trans	-55	135.3	176.1	0	0	0	0	0	108.1	H84 L88	H84-A86 VanDerWaalsContact C-N 3.3Å; H84-A86 PolarHBondContact O-N 3.2Å; A86-L88 PolarHBondContact O-N 3.47Å
87	N	26	Very low	32	Very low	135 Å²	135	117.3 Å²	117.3	72%	0.722	58%	0.579	S	S	*	*			trans	-56.7	134.3	-174.3	-132.6	-13.9	0	0	0	109.7	R85 D89 D90	R85-N87 PolarHBondContact O-N 2.92Å; N87-D89 PolarHBondContact O-N 3.15Å; N87-D90 PolarHBondContact O-N 3.37Å; N87-D90 VanDerWaalsContact O-N 3.09Å
88	L	27.5	Very low	32.5	Very low	106 Å²	106	114.4 Å²	114.4	56%	0.555	57%	0.572	S	S	*	*	T	Hydrogen-bonded Turn	trans	-57.7	-10.4	-168.6	-145.8	82.6	0	0	0	115.3	A86 R91	A86-L88 PolarHBondContact O-N 3.47Å; L88-R91 WeakPolarHBondContact O-CD 3.48Å; L88-R91 WeakPolarHBondContact O-CG 3.5Å
89	D	28.7	Very low	32.5	Very low	154 Å²	154	117.1 Å²	117.1	82%	0.824	61%	0.605	S	S	*	*	T	Hydrogen-bonded Turn	trans	-96.5	-8.8	-178.2	-78.3	-30.3	0	0	0	114.3	N87 R91	N87-D89 PolarHBondContact O-N 3.15Å; D89-R91 PolarHBondContact O-N 3.46Å
90	D	32.9	Very low	32.7	Very low	104 Å²	104	117.1 Å²	117.1	56%	0.556	60%	0.603	S	S	*	*			trans	-81.6	34.2	170.5	-87	-24.2	0	0	0	112.4	N87 L92 G93	N87-D90 PolarHBondContact O-N 3.37Å; N87-D90 VanDerWaalsContact O-N 3.09Å; D90-L92 PolarHBondContact O-N 3Å; D90-G93 PolarHBondContact O-N 2.76Å
91	R	34.3	Very low	33.2	Very low	161 Å²	161	113.4 Å²	113.4	61%	0.608	58%	0.582	S	S	*	*	T	Hydrogen-bonded Turn	trans	-59	-5.9	-170.6	-100.4	173.4	165.1	-163.4	-1.3	116.5	L88 D89	L88-R91 WeakPolarHBondContact O-CD 3.48Å; L88-R91 WeakPolarHBondContact O-CG 3.5Å; D89-R91 PolarHBondContact O-N 3.46Å
92	L	33.3	Very low	34.7	Very low	123 Å²	123	114.9 Å²	114.9	64%	0.644	59%	0.588	S	S	*	*	T	Hydrogen-bonded Turn	trans	-140.3	28.7	173.1	-70.9	172.4	0	0	0	111.3	D90 V94	D90-L92 PolarHBondContact O-N 3Å; L92-V94 PolarHBondContact O-N 2.7Å
93	G	32.4	Very low	36.6	Very low	20 Å²	20	109 Å²	109	21%	0.206	56%	0.559	C	S	.	*			trans	-51.2	17.7	-166.5	0	0	0	0	0	119.3	D90 N95	D90-G93 PolarHBondContact O-N 2.76Å; G93-N95 PolarHBondContact O-N 3Å
94	V	32.5	Very low	38.4	Very low	37 Å²	37	105.4 Å²	105.4	22%	0.224	55%	0.545	C	S	.	.			trans	-69.3	62.7	162.9	-154.2	0	0	0	0	110.5	L92 F96 S141 I143	L92-V94 PolarHBondContact O-N 2.7Å; V94-F96 HydrophobicContact CB-CE2 4.34Å; V94-F96 HydrophobicContact CG1-CD1 4.47Å; V94-F96 HydrophobicContact CG1-CD2 3.58Å; V94-F96 HydrophobicContact CG1-CE1 4.12Å; V94-F96 HydrophobicContact CG1-CE2 3.16Å; V94-F96 HydrophobicContact CG1-CG 4.22Å; V94-F96 HydrophobicContact CG1-CZ 3.46Å; V94-F96 VanDerWaalsContact CG1-CZ 3.46Å; V94-F96 PolarHBondContact O-N 2.79Å; V94-S141 WeakPolarHBondContact CG2-OG 3.49Å; V94-I143 HydrophobicContact CG1-CD1 4.47Å; V94-I143 HydrophobicContact CG1-CG1 3.98Å; V94-I143 HydrophobicContact CG2-CD1 4.02Å; V94-I143 HydrophobicContact CG2-CG1 4.33Å
95	N	30.4	Very low	40.4	Very low	119 Å²	119	102 Å²	102	64%	0.636	53%	0.53	S	S	*	.			trans	-82.7	88.8	162.6	-140.4	-14	0	0	0	106.9	G93 N97 S98	G93-N95 PolarHBondContact O-N 3Å; N95-N97 PolarHBondContact O-N 3.14Å; N95-S98 PolarHBondContact O-N 2.83Å
96	F	32.9	Very low	42.5	Very low	137 Å²	137	91 Å²	91	60%	0.601	49%	0.491	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.4	-10.3	-177.6	-82.7	-78	0	0	0	114.5	V94 G142 I143	V94-F96 HydrophobicContact CB-CE2 4.34Å; V94-F96 HydrophobicContact CG1-CD1 4.47Å; V94-F96 HydrophobicContact CG1-CD2 3.58Å; V94-F96 HydrophobicContact CG1-CE1 4.12Å; V94-F96 HydrophobicContact CG1-CE2 3.16Å; V94-F96 HydrophobicContact CG1-CG 4.22Å; V94-F96 HydrophobicContact CG1-CZ 3.46Å; V94-F96 VanDerWaalsContact CG1-CZ 3.46Å; V94-F96 PolarHBondContact O-N 2.79Å; F96-G142 WeakPolarHBondContact CZ-O 2.88Å; F96-I143 HydrophobicContact CZ-CG1 4.37Å
97	N	37.7	Very low	44.8	Very low	155 Å²	155	93.4 Å²	93.4	83%	0.829	50%	0.495	S	S	*	.	T	Hydrogen-bonded Turn	trans	-91.9	-2.5	-172.4	-74.4	-7.5	0	0	0	115.7	N95	N95-N97 PolarHBondContact O-N 3.14Å
98	S	38.3	Very low	47.5	Very low	65 Å²	65	87.9 Å²	87.9	46%	0.455	47%	0.467	S	S	.	.	S	Bend	trans	-93.7	-10.1	-178.4	68.1	0	0	0	0	115	N95 I100	N95-S98 PolarHBondContact O-N 2.83Å; S98-I100 WeakPolarHBondContact O-CG1 3.4Å; S98-I100 PolarHBondContact O-N 3.27Å
99	G	36	Very low	50.2	Low	82 Å²	82	82.8 Å²	82.8	85%	0.845	44%	0.441	S	S	*	.	S	Bend	trans	60.7	0.7	-179.7	0	0	0	0	0	115.7
100	I	41	Very low	52.8	Low	155 Å²	155	77 Å²	77	80%	0.795	41%	0.409	S	S	*	.			trans	-126	-13.4	-170.4	-62.8	167.8	0	0	0	111.7	S98 D102	S98-I100 WeakPolarHBondContact O-CG1 3.4Å; S98-I100 PolarHBondContact O-N 3.27Å; I100-D102 PolarHBondContact O-N 3.49Å
101	Y	44.7	Very low	55.2	Low	96 Å²	96	73.8 Å²	73.8	38%	0.376	39%	0.392	S	S	.	.			trans	-87.3	105.1	179.1	-150.2	-90.2	0	0	0	111.9	W103	Y101-W103 PolarHBondContact O-N 2.87Å
102	D	64.8	Low	57.8	Low	79 Å²	79	66.1 Å²	66.1	42%	0.422	36%	0.363	S	S	.	.			trans	-76.3	108.6	169.5	-166.3	-7.7	0	0	0	108.6	I100 S104 Q105	I100-D102 PolarHBondContact O-N 3.49Å; D102-S104 PolarHBondContact O-N 3.35Å; D102-S104 WeakPolarHBondContact OD1-CB 3.19Å; D102-S104 PolarHBondContact OD1-N 3.23Å; D102-S104 PolarHBondContact OD1-OG 3.19Å; D102-S104 PolarHBondContact OD2-OG 2.84Å; D102-S104 VanDerWaalsContact OD2-OG 3.08Å; D102-Q105 HydrophobicContact CB-CG 4.3Å; D102-Q105 WeakPolarHBondContact O-CB 3.49Å; D102-Q105 PolarHBondContact O-N 2.99Å
103	W	71.3	Confident	60.4	Low	33 Å²	33	60.4 Å²	60.4	13%	0.125	33%	0.333	C	S	.	.	G	3₁₀ helix	trans	-52.7	-22.7	177	65.6	-86.2	0	0	0	112.5	Y101 Q105 S106 W109 I143 T147 V148 Y151	Y101-W103 PolarHBondContact O-N 2.87Å; W103-Q105 PolarHBondContact O-N 3.03Å; W103-S106 VanDerWaalsContact O-CB 3.27Å; W103-S106 WeakPolarHBondContact O-CB 3.12Å; W103-S106 PolarHBondContact O-N 3.1Å; W103-S106 PolarHBondContact O-OG 3.23Å; W103-W109 HydrophobicContact CE3-CB 4.38Å; W103-W109 HydrophobicContact CE3-CD2 4.49Å; W103-W109 HydrophobicContact CE3-CG 4.24Å; W103-W109 HydrophobicContact CH2-CD2 4.38Å; W103-W109 HydrophobicContact CZ3-CB 4.34Å; W103-W109 AromaticContact CZ3-CD2 3.62Å; W103-W109 HydrophobicContact CZ3-CD2 3.62Å; W103-W109 AromaticContact CZ3-CE3 3.93Å; W103-W109 HydrophobicContact CZ3-CE3 3.93Å; W103-W109 AromaticContact CZ3-CG 3.79Å; W103-W109 HydrophobicContact CZ3-CG 3.79Å; W103-I143 HydrophobicContact CB-CD1 3.55Å; W103-I143 HydrophobicContact CB-CG1 4.26Å; W103-I143 HydrophobicContact CD2-CD1 4.24Å; W103-I143 HydrophobicContact CD2-CG2 4.14Å; W103-I143 HydrophobicContact CE3-CD1 4.29Å; W103-I143 HydrophobicContact CG-CD1 3.92Å; W103-I143 HydrophobicContact CG-CG1 4.42Å; W103-I143 HydrophobicContact CG-CG2 4.24Å; W103-T147 HydrophobicContact CZ2-CG2 3.98Å; W103-V148 HydrophobicContact CE3-CG2 4.38Å; W103-V148 HydrophobicContact CH2-CB 4.09Å; W103-V148 HydrophobicContact CH2-CG1 4.11Å; W103-V148 HydrophobicContact CH2-CG2 3.97Å; W103-V148 HydrophobicContact CZ2-CG2 4.42Å; W103-V148 HydrophobicContact CZ3-CB 4.36Å; W103-V148 HydrophobicContact CZ3-CG1 4.12Å; W103-V148 HydrophobicContact CZ3-CG2 3.93Å; W103-Y151 HydrophobicContact CH2-CD1 4.14Å; W103-Y151 AromaticContact CH2-CG 3.88Å; W103-Y151 HydrophobicContact CH2-CG 3.88Å; W103-Y151 HydrophobicContact CZ2-CD2 4.32Å; W103-Y151 HydrophobicContact CZ2-CG 4Å
104	S	69.8	Low	62.8	Low	1 Å²	1	61.7 Å²	61.7	1%	0.007	34%	0.335	C	S	.	.	G	3₁₀ helix	trans	-67.6	-8.8	175.3	86.1	0	0	0	0	113.9	D102 Y151	D102-S104 PolarHBondContact O-N 3.35Å; D102-S104 WeakPolarHBondContact OD1-CB 3.19Å; D102-S104 PolarHBondContact OD1-N 3.23Å; D102-S104 PolarHBondContact OD1-OG 3.19Å; D102-S104 PolarHBondContact OD2-OG 2.84Å; D102-S104 VanDerWaalsContact OD2-OG 3.08Å; S104-Y151 VanDerWaalsContact CB-CE2 3.44Å; S104-Y151 VanDerWaalsContact CB-CZ 3.5Å
105	Q	73.7	Confident	65.4	Low	96 Å²	96	60.6 Å²	60.6	45%	0.449	33%	0.33	S	S	.	.	G	3₁₀ helix	trans	-101.2	-3.4	172.9	-56.2	-58.3	-27.9	0	0	112.6	D102 W103	D102-Q105 HydrophobicContact CB-CG 4.3Å; D102-Q105 WeakPolarHBondContact O-CB 3.49Å; D102-Q105 PolarHBondContact O-N 2.99Å; W103-Q105 PolarHBondContact O-N 3.03Å
106	S	74.3	Confident	68.3	Low	15 Å²	15	54.9 Å²	54.9	11%	0.105	30%	0.299	C	S	.	.	S	Bend	trans	-65.9	140.8	177.9	67.9	0	0	0	0	111.6	W103 S108 W109 L110	W103-S106 VanDerWaalsContact O-CB 3.27Å; W103-S106 WeakPolarHBondContact O-CB 3.12Å; W103-S106 PolarHBondContact O-N 3.1Å; W103-S106 PolarHBondContact O-OG 3.23Å; S106-S108 PolarHBondContact O-N 3.24Å; S106-W109 PolarHBondContact O-N 3.44Å; S106-W109 PolarHBondContact OG-N 3.1Å; S106-L110 WeakPolarHBondContact O-CG 3.48Å; S106-L110 PolarHBondContact O-N 3.31Å
107	E	78.3	Confident	70.8	Confident	88 Å²	88	48.4 Å²	48.4	41%	0.411	27%	0.271	S	S	.	.	H	α-helix	trans	-53.5	-40.5	179	-174.5	178.6	-161.7	0	0	112	W109 L110 I111	E107-W109 VanDerWaalsContact C-N 3.33Å; E107-W109 PolarHBondContact O-N 3.49Å; E107-L110 PolarHBondContact O-N 2.86Å; E107-I111 HydrophobicContact CG-CD1 4.05Å; E107-I111 WeakPolarHBondContact O-CG1 3.45Å; E107-I111 PolarHBondContact O-N 2.99Å
108	S	82.5	Confident	73	Confident	19 Å²	19	42.7 Å²	42.7	13%	0.133	24%	0.24	C	C	.	.	H	α-helix	trans	-56.8	-45.1	176.2	-66.1	0	0	0	0	112.6	S106 V112 N134	S106-S108 PolarHBondContact O-N 3.24Å; S108-V112 WeakPolarHBondContact O-CG2 3.32Å; S108-V112 PolarHBondContact O-N 3.43Å; S108-N134 VanDerWaalsContact CA-OD1 3.25Å; S108-N134 WeakPolarHBondContact CA-OD1 3.25Å; S108-N134 WeakPolarHBondContact CB-OD1 3.45Å; S108-N134 WeakPolarHBondContact O-CB 3.46Å; S108-N134 PolarHBondContact OG-OD1 3.16Å
109	W	85.5	Confident	75.3	Confident	0 Å²	0	39.6 Å²	39.6	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-71.7	-39.4	176.7	175.6	-105.6	0	0	0	111.8	W103 S106 E107 I111 V112 Q113 M135 L138 V148 Y151 C152 V156	W103-W109 HydrophobicContact CE3-CB 4.38Å; W103-W109 HydrophobicContact CE3-CD2 4.49Å; W103-W109 HydrophobicContact CE3-CG 4.24Å; W103-W109 HydrophobicContact CH2-CD2 4.38Å; W103-W109 HydrophobicContact CZ3-CB 4.34Å; W103-W109 AromaticContact CZ3-CD2 3.62Å; W103-W109 HydrophobicContact CZ3-CD2 3.62Å; W103-W109 AromaticContact CZ3-CE3 3.93Å; W103-W109 HydrophobicContact CZ3-CE3 3.93Å; W103-W109 AromaticContact CZ3-CG 3.79Å; W103-W109 HydrophobicContact CZ3-CG 3.79Å; S106-W109 PolarHBondContact O-N 3.44Å; S106-W109 PolarHBondContact OG-N 3.1Å; E107-W109 VanDerWaalsContact C-N 3.33Å; E107-W109 PolarHBondContact O-N 3.49Å; W109-I111 VanDerWaalsContact C-N 3.25Å; W109-I111 PolarHBondContact O-N 3.38Å; W109-V112 HydrophobicContact CE3-CB 4Å; W109-V112 HydrophobicContact CE3-CG1 3.93Å; W109-V112 HydrophobicContact CH2-CG1 4.49Å; W109-V112 HydrophobicContact CZ3-CB 4.25Å; W109-V112 HydrophobicContact CZ3-CG1 3.65Å; W109-V112 PolarHBondContact O-N 3.1Å; W109-Q113 HydrophobicContact CZ2-CB 4.03Å; W109-Q113 WeakPolarHBondContact O-CG 3.41Å; W109-Q113 PolarHBondContact O-N 3.03Å; W109-M135 HydrophobicContact CZ3-SD 4.39Å; W109-L138 HydrophobicContact CB-CD1 3.89Å; W109-L138 HydrophobicContact CB-CD2 4.43Å; W109-L138 HydrophobicContact CE3-CD1 3.95Å; W109-V148 HydrophobicContact CE3-CG1 4.09Å; W109-V148 HydrophobicContact CH2-CG1 4.05Å; W109-V148 HydrophobicContact CZ3-CG1 3.54Å; W109-Y151 AromaticContact CE2-CD1 3.89Å; W109-Y151 AromaticContact CE2-CE1 3.93Å; W109-Y151 AromaticContact CZ2-CD1 3.64Å; W109-Y151 HydrophobicContact CZ2-CD1 3.64Å; W109-Y151 AromaticContact CZ2-CE1 3.98Å; W109-Y151 HydrophobicContact CZ2-CE1 3.98Å; W109-Y151 AromaticContact NE1-CD1 3.81Å; W109-Y151 AromaticContact NE1-CE1 3.4Å; W109-C152 HydrophobicContact CH2-CB 3.96Å; W109-C152 HydrophobicContact CZ2-CB 4.47Å; W109-V156 HydrophobicContact CZ2-CG2 3.81Å
110	L	82	Confident	77.7	Confident	31 Å²	31	35.8 Å²	35.8	16%	0.162	18%	0.179	C	C	.	.	H	α-helix	trans	-56.1	-42	176.5	-62.9	-176.9	0	0	0	111.3	Y83 S106 E107 Q113 N114	Y83-L110 HydrophobicContact CD1-CD1 4.25Å; Y83-L110 HydrophobicContact CE1-CD1 4.16Å; Y83-L110 HydrophobicContact CE1-CD2 4.05Å; S106-L110 WeakPolarHBondContact O-CG 3.48Å; S106-L110 PolarHBondContact O-N 3.31Å; E107-L110 PolarHBondContact O-N 2.86Å; L110-Q113 WeakPolarHBondContact O-CG 3.32Å; L110-N114 WeakPolarHBondContact O-CB 3.39Å; L110-N114 PolarHBondContact O-N 2.89Å; L110-N114 PolarHBondContact O-ND2 3.29Å; L110-N114 PolarHBondContact O-OD1 3.08Å
111	I	84	Confident	79.7	Confident	37 Å²	37	28.5 Å²	28.5	19%	0.19	14%	0.142	C	C	.	.	H	α-helix	trans	-63.2	-46.3	174.9	-67.7	165.2	0	0	0	111.2	E107 W109 N114 A115 E130	E107-I111 HydrophobicContact CG-CD1 4.05Å; E107-I111 WeakPolarHBondContact O-CG1 3.45Å; E107-I111 PolarHBondContact O-N 2.99Å; W109-I111 VanDerWaalsContact C-N 3.25Å; W109-I111 PolarHBondContact O-N 3.38Å; I111-N114 PolarHBondContact O-N 2.97Å; I111-A115 PolarHBondContact O-N 3.44Å; I111-E130 HydrophobicContact CD1-CG 4.45Å; I111-E130 HydrophobicContact CG2-CB 4.46Å; I111-E130 HydrophobicContact CG2-CG 4.02Å
112	V	89.1	Confident	81.3	Confident	0 Å²	0	25.7 Å²	25.7	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-62.4	-50.3	-179.9	172.3	0	0	0	0	111.4	S108 W109 N114 A115 I116 A131 N134 M135 L138 I198	S108-V112 WeakPolarHBondContact O-CG2 3.32Å; S108-V112 PolarHBondContact O-N 3.43Å; W109-V112 HydrophobicContact CE3-CB 4Å; W109-V112 HydrophobicContact CE3-CG1 3.93Å; W109-V112 HydrophobicContact CH2-CG1 4.49Å; W109-V112 HydrophobicContact CZ3-CB 4.25Å; W109-V112 HydrophobicContact CZ3-CG1 3.65Å; W109-V112 PolarHBondContact O-N 3.1Å; V112-N114 VanDerWaalsContact C-N 3.32Å; V112-N114 PolarHBondContact O-N 3.13Å; V112-A115 PolarHBondContact O-N 3.25Å; V112-I116 HydrophobicContact CG1-CD1 3.84Å; V112-I116 WeakPolarHBondContact O-CG1 3.44Å; V112-I116 PolarHBondContact O-N 3Å; V112-A131 WeakPolarHBondContact CG2-O 3.44Å; V112-N134 HydrophobicContact CG2-CB 3.84Å; V112-M135 HydrophobicContact CG1-SD 3.93Å; V112-M135 HydrophobicContact CG2-CB 4.01Å; V112-L138 HydrophobicContact CG2-CD1 4.3Å; V112-I198 HydrophobicContact CG1-CG2 3.99Å
113	Q	86.8	Confident	81.8	Confident	3 Å²	3	24.7 Å²	24.7	1%	0.014	13%	0.127	C	C	.	.	H	α-helix	trans	-64.6	-37.9	-179.9	72.5	180	-7.7	0	0	111.7	L62 W109 L110 A115 I116 I117 V156	L62-Q113 HydrophobicContact CD1-CG 4.28Å; W109-Q113 HydrophobicContact CZ2-CB 4.03Å; W109-Q113 WeakPolarHBondContact O-CG 3.41Å; W109-Q113 PolarHBondContact O-N 3.03Å; L110-Q113 WeakPolarHBondContact O-CG 3.32Å; Q113-A115 VanDerWaalsContact C-N 3.32Å; Q113-A115 PolarHBondContact O-N 3.31Å; Q113-I116 PolarHBondContact O-N 3.44Å; Q113-I117 WeakPolarHBondContact O-CB 3.5Å; Q113-I117 VanDerWaalsContact O-CG1 3.25Å; Q113-I117 WeakPolarHBondContact O-CG1 3.4Å; Q113-I117 PolarHBondContact O-N 2.9Å; Q113-V156 HydrophobicContact CB-CG1 4.39Å; Q113-V156 HydrophobicContact CB-CG2 3.95Å
114	N	83.5	Confident	81.3	Confident	48 Å²	48	28.2 Å²	28.2	26%	0.257	15%	0.154	S	C	.	.	H	α-helix	trans	-63.8	-41.5	178.3	-73.8	-10.6	0	0	0	111.2	T58 L110 I111 V112 I117 N118	T58-N114 HydrophobicContact CG2-CB 4.26Å; T58-N114 WeakPolarHBondContact CG2-OD1 3.49Å; L110-N114 WeakPolarHBondContact O-CB 3.39Å; L110-N114 PolarHBondContact O-N 2.89Å; L110-N114 PolarHBondContact O-ND2 3.29Å; L110-N114 PolarHBondContact O-OD1 3.08Å; I111-N114 PolarHBondContact O-N 2.97Å; V112-N114 VanDerWaalsContact C-N 3.32Å; V112-N114 PolarHBondContact O-N 3.13Å; N114-I117 PolarHBondContact O-N 3.3Å; N114-N118 WeakPolarHBondContact O-CB 3.33Å; N114-N118 PolarHBondContact O-N 2.88Å; N114-N118 PolarHBondContact O-ND2 2.91Å
115	A	87.4	Confident	80.9	Confident	13 Å²	13	35.7 Å²	35.7	11%	0.107	19%	0.194	C	C	.	.	H	α-helix	trans	-60.6	-49.4	173.6	0	0	0	0	0	111.2	I111 V112 Q113 I117 N118 I119 A131 I198	I111-A115 PolarHBondContact O-N 3.44Å; V112-A115 PolarHBondContact O-N 3.25Å; Q113-A115 VanDerWaalsContact C-N 3.32Å; Q113-A115 PolarHBondContact O-N 3.31Å; A115-I117 PolarHBondContact O-N 3.13Å; A115-N118 PolarHBondContact O-N 3.47Å; A115-I119 HydrophobicContact CB-CD1 4.43Å; A115-I119 WeakPolarHBondContact O-CB 3.19Å; A115-I119 VanDerWaalsContact O-CD1 3.25Å; A115-I119 WeakPolarHBondContact O-CD1 3.48Å; A115-I119 WeakPolarHBondContact O-CG1 3.37Å; A115-I119 PolarHBondContact O-N 3.5Å; A115-A131 HydrophobicContact CB-CB 3.54Å; A115-I198 HydrophobicContact CB-CD1 4.22Å
116	I	90.5	Very high	80.6	Confident	0 Å²	0	32.6 Å²	32.6	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-57.4	-47.9	179	-66.4	163.1	0	0	0	111.1	V112 Q113 N118 I119 I120 V156 L157 I195 I198 F199	V112-I116 HydrophobicContact CG1-CD1 3.84Å; V112-I116 WeakPolarHBondContact O-CG1 3.44Å; V112-I116 PolarHBondContact O-N 3Å; Q113-I116 PolarHBondContact O-N 3.44Å; I116-N118 PolarHBondContact O-N 2.91Å; I116-I119 PolarHBondContact O-N 3.5Å; I116-I120 HydrophobicContact CG2-CD1 3.94Å; I116-I120 WeakPolarHBondContact O-CG1 3.39Å; I116-I120 PolarHBondContact O-N 3.02Å; I116-V156 HydrophobicContact CG2-CG1 4.15Å; I116-L157 HydrophobicContact CG2-CD2 4.22Å; I116-I195 HydrophobicContact CG2-CD1 4.26Å; I116-I198 HydrophobicContact CG1-CD1 4.3Å; I116-F199 HydrophobicContact CD1-CE2 3.58Å; I116-F199 HydrophobicContact CD1-CZ 3.88Å; I116-F199 HydrophobicContact CG1-CE2 4.38Å
117	I	85.9	Confident	80.6	Confident	1 Å²	1	35.9 Å²	35.9	1%	0.005	20%	0.197	C	C	.	.	H	α-helix	trans	-59.3	-49.2	179.5	-69.4	166.4	0	0	0	110.2	T58 L61 L62 Q113 N114 A115 I119 I120 L121 V156 T160	T58-I117 HydrophobicContact CG2-CB 4.02Å; T58-I117 HydrophobicContact CG2-CD1 3.4Å; T58-I117 VanDerWaalsContact CG2-CD1 3.4Å; T58-I117 HydrophobicContact CG2-CG1 4.28Å; T58-I117 HydrophobicContact CG2-CG2 3.94Å; L61-I117 HydrophobicContact CD1-CG2 3.67Å; L62-I117 HydrophobicContact CD1-CD1 4.32Å; L62-I117 HydrophobicContact CD2-CD1 4.11Å; L62-I117 HydrophobicContact CG-CD1 4.22Å; Q113-I117 WeakPolarHBondContact O-CB 3.5Å; Q113-I117 VanDerWaalsContact O-CG1 3.25Å; Q113-I117 WeakPolarHBondContact O-CG1 3.4Å; Q113-I117 PolarHBondContact O-N 2.9Å; N114-I117 PolarHBondContact O-N 3.3Å; A115-I117 PolarHBondContact O-N 3.13Å; I117-I119 PolarHBondContact O-N 3.04Å; I117-I120 PolarHBondContact O-N 3.35Å; I117-L121 HydrophobicContact CG2-CD1 3.7Å; I117-L121 HydrophobicContact CG2-CG 4.39Å; I117-L121 WeakPolarHBondContact O-CB 3.43Å; I117-L121 WeakPolarHBondContact O-CG 3.44Å; I117-L121 PolarHBondContact O-N 2.91Å; I117-V156 HydrophobicContact CD1-CG1 4.16Å; I117-V156 HydrophobicContact CG1-CG1 3.8Å; I117-T160 WeakPolarHBondContact CG1-OG1 3.4Å; I117-T160 HydrophobicContact CG2-CG2 4.36Å
118	N	83.3	Confident	80.9	Confident	35 Å²	35	32.6 Å²	32.6	19%	0.187	18%	0.182	C	C	.	.	H	α-helix	trans	-66.2	-36.3	-178.7	-71.2	-17.7	0	0	0	112.7	N114 A115 I116 L121 C122 K123 L126	N114-N118 WeakPolarHBondContact O-CB 3.33Å; N114-N118 PolarHBondContact O-N 2.88Å; N114-N118 PolarHBondContact O-ND2 2.91Å; A115-N118 PolarHBondContact O-N 3.47Å; I116-N118 PolarHBondContact O-N 2.91Å; N118-L121 PolarHBondContact O-N 3.3Å; N118-C122 PolarHBondContact O-N 2.89Å; N118-K123 HydrophobicContact CB-CB 4.04Å; N118-K123 HydrophobicContact CB-CG 4.32Å; N118-K123 PolarHBondContact O-N 2.84Å; N118-K123 WeakPolarHBondContact OD1-CD 3.42Å; N118-L126 HydrophobicContact CB-CD2 3.4Å; N118-L126 VanDerWaalsContact CB-CD2 3.4Å
119	I	86.6	Confident	81.1	Confident	0 Å²	0	34 Å²	34	0%	0	19%	0.192	C	C	.	.	H	α-helix	trans	-64.1	-38	175.1	-71.4	158.3	0	0	0	111.8	A115 I116 I117 L126 I128 S191 I194 I195 I198	A115-I119 HydrophobicContact CB-CD1 4.43Å; A115-I119 WeakPolarHBondContact O-CB 3.19Å; A115-I119 VanDerWaalsContact O-CD1 3.25Å; A115-I119 WeakPolarHBondContact O-CD1 3.48Å; A115-I119 WeakPolarHBondContact O-CG1 3.37Å; A115-I119 PolarHBondContact O-N 3.5Å; I116-I119 PolarHBondContact O-N 3.5Å; I117-I119 PolarHBondContact O-N 3.04Å; I119-L126 HydrophobicContact CB-CD1 4.32Å; I119-L126 HydrophobicContact CG1-CD1 3.74Å; I119-L126 HydrophobicContact CG1-CD2 4.4Å; I119-L126 HydrophobicContact CG1-CG 4.5Å; I119-I128 HydrophobicContact CD1-CG2 4.01Å; I119-S191 PolarHBondContact O-OG 3.47Å; I119-I194 HydrophobicContact CD1-CG2 3.5Å; I119-I194 HydrophobicContact CG1-CG2 4.02Å; I119-I194 HydrophobicContact CG2-CB 4.26Å; I119-I194 HydrophobicContact CG2-CG2 4.24Å; I119-I195 HydrophobicContact CG2-CD1 4.36Å; I119-I195 HydrophobicContact CG2-CG1 4.08Å; I119-I198 HydrophobicContact CD1-CD1 3.47Å; I119-I198 VanDerWaalsContact CD1-CD1 3.47Å
120	I	86.4	Confident	81.1	Confident	2 Å²	2	38.3 Å²	38.3	1%	0.01	21%	0.212	C	C	.	.	H	α-helix	trans	-76.9	-37	178.5	-66.4	170.9	0	0	0	111	I116 I117 C122 L157 T160 L164 Y187 I195	I116-I120 HydrophobicContact CG2-CD1 3.94Å; I116-I120 WeakPolarHBondContact O-CG1 3.39Å; I116-I120 PolarHBondContact O-N 3.02Å; I117-I120 PolarHBondContact O-N 3.35Å; I120-C122 PolarHBondContact O-N 3.29Å; I120-L157 HydrophobicContact CD1-CD2 3.49Å; I120-L157 VanDerWaalsContact CD1-CD2 3.49Å; I120-T160 HydrophobicContact CB-CG2 3.7Å; I120-T160 HydrophobicContact CD1-CG2 4.2Å; I120-T160 HydrophobicContact CG2-CG2 3.53Å; I120-L164 HydrophobicContact CG2-CD2 4.04Å; I120-Y187 HydrophobicContact CG1-CE2 4.43Å; I120-I195 HydrophobicContact CD1-CD1 4.01Å; I120-I195 HydrophobicContact CG1-CD1 3.82Å
121	L	82.3	Confident	81.4	Confident	2 Å²	2	36.9 Å²	36.9	1%	0.01	21%	0.205	C	C	.	.	T	Hydrogen-bonded Turn	trans	-86.9	17.3	-179.2	-60.5	-180	0	0	0	113.8	Y55 L61 I117 N118 K123 T160 T163	Y55-L121 HydrophobicContact CD1-CD2 3.9Å; Y55-L121 HydrophobicContact CD2-CB 4.04Å; Y55-L121 HydrophobicContact CE1-CD2 3.96Å; Y55-L121 HydrophobicContact CE2-CB 4.4Å; Y55-L121 HydrophobicContact CG-CB 4.24Å; Y55-L121 HydrophobicContact CG-CD1 4.32Å; Y55-L121 HydrophobicContact CG-CD2 4.2Å; Y55-L121 HydrophobicContact CG-CG 4.49Å; L61-L121 HydrophobicContact CD1-CD1 3.75Å; I117-L121 HydrophobicContact CG2-CD1 3.7Å; I117-L121 HydrophobicContact CG2-CG 4.39Å; I117-L121 WeakPolarHBondContact O-CB 3.43Å; I117-L121 WeakPolarHBondContact O-CG 3.44Å; I117-L121 PolarHBondContact O-N 2.91Å; N118-L121 PolarHBondContact O-N 3.3Å; L121-K123 VanDerWaalsContact C-N 3.26Å; L121-K123 HydrophobicContact CB-CG 4.49Å; L121-K123 PolarHBondContact O-N 3.48Å; L121-T160 HydrophobicContact CD1-CG2 4.2Å; L121-T160 HydrophobicContact CD2-CG2 3.85Å; L121-T160 HydrophobicContact CG-CG2 3.74Å; L121-T163 HydrophobicContact CD1-CG2 4.28Å; L121-T163 HydrophobicContact CD2-CG2 3.92Å
122	C	79	Confident	81.7	Confident	36 Å²	36	35.1 Å²	35.1	24%	0.243	20%	0.196	C	C	.	.	T	Hydrogen-bonded Turn	trans	55.9	30.9	175.5	-44.6	0	0	0	0	115.4	N118 I120 Y186	N118-C122 PolarHBondContact O-N 2.89Å; I120-C122 PolarHBondContact O-N 3.29Å; C122-Y186 VanDerWaalsContact CA-OH 3.32Å; C122-Y186 WeakPolarHBondContact CA-OH 3.28Å; C122-Y186 HydrophobicContact CB-CE1 3.92Å; C122-Y186 HydrophobicContact CB-CE2 4.11Å; C122-Y186 WeakPolarHBondContact SG-CD1 3.43Å; C122-Y186 WeakPolarHBondContact SG-CE1 3.4Å
123	K	75.9	Confident	81.6	Confident	59 Å²	59	40.7 Å²	40.7	26%	0.257	22%	0.217	S	C	.	.			trans	-72.6	141.3	-179.6	-59.5	-152.4	-175.7	177.3	0	110.8	W56 N118 L121 L126	W56-K123 PolarHBondContact O-NZ 3.37Å; N118-K123 HydrophobicContact CB-CB 4.04Å; N118-K123 HydrophobicContact CB-CG 4.32Å; N118-K123 PolarHBondContact O-N 2.84Å; N118-K123 WeakPolarHBondContact OD1-CD 3.42Å; L121-K123 VanDerWaalsContact C-N 3.26Å; L121-K123 HydrophobicContact CB-CG 4.49Å; L121-K123 PolarHBondContact O-N 3.48Å; K123-L126 WeakPolarHBondContact O-CD1 3.47Å; K123-L126 WeakPolarHBondContact O-CG 3.19Å
124	P	61.1	Low	81.7	Confident	107 Å²	107	40.8 Å²	40.8	70%	0.695	22%	0.218	S	C	*	.	S	Bend	trans	-69.4	168.5	179.7	28.4	-34.6	0	0	0	112.7
125	D	59.6	Low	82	Confident	158 Å²	158	38.5 Å²	38.5	85%	0.845	21%	0.205	S	C	*	.			trans	56.8	49.1	170.4	-59	-39.4	0	0	0	115.8	D127	D125-D127 PolarHBondContact O-N 3.17Å
126	L	68.1	Low	81.9	Confident	30 Å²	30	42.7 Å²	42.7	16%	0.157	22%	0.218	C	C	.	.			trans	-86.2	92.8	-178	-68.6	163.2	0	0	0	112.2	N118 I119 K123 I128 Y190	N118-L126 HydrophobicContact CB-CD2 3.4Å; N118-L126 VanDerWaalsContact CB-CD2 3.4Å; I119-L126 HydrophobicContact CB-CD1 4.32Å; I119-L126 HydrophobicContact CG1-CD1 3.74Å; I119-L126 HydrophobicContact CG1-CD2 4.4Å; I119-L126 HydrophobicContact CG1-CG 4.5Å; K123-L126 WeakPolarHBondContact O-CD1 3.47Å; K123-L126 WeakPolarHBondContact O-CG 3.19Å; L126-I128 PolarHBondContact O-N 2.86Å; L126-Y190 HydrophobicContact CD1-CE1 4.46Å
127	D	75.6	Confident	81.7	Confident	85 Å²	85	46.1 Å²	46.1	46%	0.455	23%	0.234	S	C	.	.			trans	-74.7	106.5	160.6	-168.6	0	0	0	0	110.8	M37 D125 S129	M37-D127 HydrophobicContact CE-CB 3.92Å; M37-D127 HydrophobicContact SD-CB 3.85Å; D125-D127 PolarHBondContact O-N 3.17Å; D127-S129 WeakPolarHBondContact OD1-CB 3.38Å; D127-S129 PolarHBondContact OD1-N 2.97Å; D127-S129 PolarHBondContact OD1-OG 2.96Å
128	I	83.8	Confident	81.6	Confident	18 Å²	18	46.3 Å²	46.3	9%	0.092	24%	0.235	C	C	.	.			trans	-88.1	-7.8	178.6	70.1	174.3	0	0	0	112.8	F27 I119 L126 E130 A131 V132 I194 L197	F27-I128 HydrophobicContact CD2-CD1 4.32Å; F27-I128 HydrophobicContact CE2-CD1 4.17Å; F27-I128 HydrophobicContact CE2-CG1 4.05Å; I119-I128 HydrophobicContact CD1-CG2 4.01Å; L126-I128 PolarHBondContact O-N 2.86Å; I128-E130 PolarHBondContact O-N 3.44Å; I128-A131 PolarHBondContact O-N 3.48Å; I128-A131 VanDerWaalsContact O-N 3.13Å; I128-V132 HydrophobicContact CG1-CG2 4.4Å; I128-V132 VanDerWaalsContact O-CG2 3.29Å; I128-V132 WeakPolarHBondContact O-CG2 3.5Å; I128-V132 PolarHBondContact O-N 3.09Å; I128-I194 HydrophobicContact CD1-CG2 3.9Å; I128-I194 HydrophobicContact CG2-CG2 3.74Å; I128-L197 HydrophobicContact CD1-CB 4.32Å; I128-L197 HydrophobicContact CD1-CD1 4.17Å
129	S	86.3	Confident	81.5	Confident	49 Å²	49	45.9 Å²	45.9	34%	0.343	23%	0.233	S	C	.	.	H	α-helix	trans	-59.5	-40.7	-173.7	-50.1	0	0	0	0	110.8	D127 R133	D127-S129 WeakPolarHBondContact OD1-CB 3.38Å; D127-S129 PolarHBondContact OD1-N 2.97Å; D127-S129 PolarHBondContact OD1-OG 2.96Å; S129-R133 WeakPolarHBondContact O-CB 3.45Å; S129-R133 PolarHBondContact O-N 3.41Å
130	E	85.7	Confident	81.3	Confident	90 Å²	90	52 Å²	52	42%	0.421	27%	0.265	S	S	.	.	H	α-helix	trans	-69.9	-40.4	177.5	-167.6	169.2	-153.6	0	0	112.3	I111 I128 R133 N134	I111-E130 HydrophobicContact CD1-CG 4.45Å; I111-E130 HydrophobicContact CG2-CB 4.46Å; I111-E130 HydrophobicContact CG2-CG 4.02Å; I128-E130 PolarHBondContact O-N 3.44Å; E130-R133 PolarHBondContact O-N 3.49Å; E130-R133 IonicContact OE1-NH2 2.59Å; E130-R133 PolarHBondContact OE1-NH2 3.14Å; E130-N134 VanDerWaalsContact CG-ND2 3.35Å; E130-N134 WeakPolarHBondContact CG-ND2 3.45Å; E130-N134 WeakPolarHBondContact O-CB 3.19Å; E130-N134 PolarHBondContact O-N 3.39Å; E130-N134 PolarHBondContact O-ND2 2.85Å
131	A	89.2	Confident	81	Confident	1 Å²	1	53.4 Å²	53.4	1%	0.008	28%	0.275	C	S	.	.	H	α-helix	trans	-63.2	-43.6	174.9	0	0	0	0	0	111.7	V112 A115 I128 R133 N134 M135 I198	V112-A131 WeakPolarHBondContact CG2-O 3.44Å; A115-A131 HydrophobicContact CB-CB 3.54Å; I128-A131 PolarHBondContact O-N 3.48Å; I128-A131 VanDerWaalsContact O-N 3.13Å; A131-R133 VanDerWaalsContact C-N 3.35Å; A131-R133 PolarHBondContact O-N 3.35Å; A131-N134 PolarHBondContact O-N 3.25Å; A131-M135 WeakPolarHBondContact O-CB 3.32Å; A131-M135 PolarHBondContact O-N 3.33Å; A131-I198 HydrophobicContact CB-CD1 4.12Å; A131-I198 HydrophobicContact CB-CG1 4.25Å
132	V	89.3	Confident	80.7	Confident	1 Å²	1	55.6 Å²	55.6	1%	0.006	30%	0.299	C	S	.	.	H	α-helix	trans	-60.2	-45	175.6	172.4	0	0	0	0	110.7	F27 I128 R136 I198	F27-V132 HydrophobicContact CE1-CG1 4.23Å; F27-V132 HydrophobicContact CE1-CG2 4.45Å; F27-V132 HydrophobicContact CZ-CB 4.25Å; F27-V132 HydrophobicContact CZ-CG1 4.17Å; F27-V132 HydrophobicContact CZ-CG2 3.93Å; I128-V132 HydrophobicContact CG1-CG2 4.4Å; I128-V132 VanDerWaalsContact O-CG2 3.29Å; I128-V132 WeakPolarHBondContact O-CG2 3.5Å; I128-V132 PolarHBondContact O-N 3.09Å; V132-R136 VanDerWaalsContact CG1-NH2 3.28Å; V132-R136 WeakPolarHBondContact O-CG 3.03Å; V132-R136 PolarHBondContact O-N 3.17Å; V132-I198 HydrophobicContact CG2-CG1 4.23Å
133	R	87.9	Confident	80.8	Confident	116 Å²	116	54.4 Å²	54.4	44%	0.438	29%	0.29	S	S	.	.	H	α-helix	trans	-62.2	-48	177.9	-178.5	-175.6	64.4	148.5	-3	111.7	S129 E130 A131 R136 Q137	S129-R133 WeakPolarHBondContact O-CB 3.45Å; S129-R133 PolarHBondContact O-N 3.41Å; E130-R133 PolarHBondContact O-N 3.49Å; E130-R133 IonicContact OE1-NH2 2.59Å; E130-R133 PolarHBondContact OE1-NH2 3.14Å; A131-R133 VanDerWaalsContact C-N 3.35Å; A131-R133 PolarHBondContact O-N 3.35Å; R133-R136 PolarHBondContact O-N 2.98Å; R133-Q137 WeakPolarHBondContact O-CG 3.34Å; R133-Q137 PolarHBondContact O-N 2.77Å
134	N	87.2	Confident	81.1	Confident	6 Å²	6	58.1 Å²	58.1	3%	0.032	31%	0.308	C	S	.	.	H	α-helix	trans	-66.7	-37.8	-178.8	-81.3	-75	0	0	0	112.2	S108 V112 E130 A131 R136 Q137 L138	S108-N134 VanDerWaalsContact CA-OD1 3.25Å; S108-N134 WeakPolarHBondContact CA-OD1 3.25Å; S108-N134 WeakPolarHBondContact CB-OD1 3.45Å; S108-N134 WeakPolarHBondContact O-CB 3.46Å; S108-N134 PolarHBondContact OG-OD1 3.16Å; V112-N134 HydrophobicContact CG2-CB 3.84Å; E130-N134 VanDerWaalsContact CG-ND2 3.35Å; E130-N134 WeakPolarHBondContact CG-ND2 3.45Å; E130-N134 WeakPolarHBondContact O-CB 3.19Å; E130-N134 PolarHBondContact O-N 3.39Å; E130-N134 PolarHBondContact O-ND2 2.85Å; A131-N134 PolarHBondContact O-N 3.25Å; N134-R136 VanDerWaalsContact C-N 3.33Å; N134-R136 PolarHBondContact O-N 3.45Å; N134-Q137 PolarHBondContact O-N 2.88Å; N134-L138 WeakPolarHBondContact O-CG 3.05Å; N134-L138 PolarHBondContact O-N 3.49Å
135	M	89.9	Confident	82.2	Confident	0 Å²	0	55.2 Å²	55.2	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-61.7	-41.4	174.6	-169.9	67	-155.6	0	0	111.7	W109 V112 A131 Q137 L138 I139 V148 I198 F199 V202	W109-M135 HydrophobicContact CZ3-SD 4.39Å; V112-M135 HydrophobicContact CG1-SD 3.93Å; V112-M135 HydrophobicContact CG2-CB 4.01Å; A131-M135 WeakPolarHBondContact O-CB 3.32Å; A131-M135 PolarHBondContact O-N 3.33Å; M135-Q137 VanDerWaalsContact C-N 3.35Å; M135-L138 PolarHBondContact O-N 2.95Å; M135-I139 HydrophobicContact CE-CD1 3.66Å; M135-I139 HydrophobicContact CE-CG1 3.72Å; M135-I139 WeakPolarHBondContact O-CG1 3.4Å; M135-I139 PolarHBondContact O-N 3.01Å; M135-I139 VanDerWaalsContact O-N 3.12Å; M135-V148 HydrophobicContact CE-CG1 3.73Å; M135-V148 HydrophobicContact SD-CG1 4.42Å; M135-I198 HydrophobicContact CB-CG2 4.1Å; M135-I198 WeakPolarHBondContact CB-O 3.43Å; M135-I198 HydrophobicContact CG-CG2 4.29Å; M135-I198 WeakPolarHBondContact CG-O 3.38Å; M135-F199 HydrophobicContact CE-CD1 3.49Å; M135-F199 VanDerWaalsContact CE-CD1 3.49Å; M135-F199 HydrophobicContact CE-CE1 3.39Å; M135-F199 HydrophobicContact CE-CZ 4.42Å; M135-F199 HydrophobicContact CG-CD1 4.42Å; M135-F199 HydrophobicContact SD-CD1 4.08Å; M135-F199 HydrophobicContact SD-CE1 3.83Å; M135-F199 HydrophobicContact SD-CZ 4.37Å; M135-V202 HydrophobicContact CE-CG2 4.26Å
136	R	86.7	Confident	83.4	Confident	100 Å²	100	50.9 Å²	50.9	38%	0.377	27%	0.274	S	S	.	.	H	α-helix	trans	-62.4	-42.4	173.7	-67.2	-172.2	-133.7	175.6	3.2	112.1	V132 R133 N134 I139 N140 T201	V132-R136 VanDerWaalsContact CG1-NH2 3.28Å; V132-R136 WeakPolarHBondContact O-CG 3.03Å; V132-R136 PolarHBondContact O-N 3.17Å; R133-R136 PolarHBondContact O-N 2.98Å; N134-R136 VanDerWaalsContact C-N 3.33Å; N134-R136 PolarHBondContact O-N 3.45Å; R136-I139 PolarHBondContact O-N 3.47Å; R136-N140 VanDerWaalsContact O-CB 3.3Å; R136-N140 WeakPolarHBondContact O-CB 3.27Å; R136-N140 PolarHBondContact O-N 2.82Å; R136-N140 PolarHBondContact O-ND2 2.7Å; R136-T201 HydrophobicContact CB-CG2 4.36Å; R136-T201 HydrophobicContact CG-CG2 3.7Å
137	Q	85.1	Confident	84.1	Confident	72 Å²	72	52 Å²	52	34%	0.336	28%	0.283	S	S	.	.	H	α-helix	trans	-62.8	-44.4	178.3	-73.8	174.8	-29.1	0	0	111.8	R133 N134 M135 N140 S141	R133-Q137 WeakPolarHBondContact O-CG 3.34Å; R133-Q137 PolarHBondContact O-N 2.77Å; N134-Q137 PolarHBondContact O-N 2.88Å; M135-Q137 VanDerWaalsContact C-N 3.35Å; Q137-N140 CarbonylContact O-C 3.55Å; Q137-N140 PolarHBondContact O-N 3.3Å; Q137-S141 WeakPolarHBondContact O-CB 3.34Å; Q137-S141 PolarHBondContact O-N 3.4Å
138	L	83.8	Confident	84.6	Confident	5 Å²	5	48 Å²	48	3%	0.026	26%	0.261	C	S	.	.	H	α-helix	trans	-62.3	-42	177.6	-72.9	167.7	0	0	0	113.1	W109 V112 N134 M135 N140 S141 I143	W109-L138 HydrophobicContact CB-CD1 3.89Å; W109-L138 HydrophobicContact CB-CD2 4.43Å; W109-L138 HydrophobicContact CE3-CD1 3.95Å; V112-L138 HydrophobicContact CG2-CD1 4.3Å; N134-L138 WeakPolarHBondContact O-CG 3.05Å; N134-L138 PolarHBondContact O-N 3.49Å; M135-L138 PolarHBondContact O-N 2.95Å; L138-N140 VanDerWaalsContact C-N 3.32Å; L138-S141 PolarHBondContact O-N 3.11Å; L138-S141 PolarHBondContact O-OG 2.89Å; L138-I143 HydrophobicContact CD2-CD1 3.92Å
139	I	82.6	Confident	84.9	Confident	27 Å²	27	47.8 Å²	47.8	14%	0.138	26%	0.26	C	S	.	.	H	α-helix	trans	-68.8	-35.5	176.8	-64.2	-54.9	0	0	0	111	M135 R136 S141 T145 V148	M135-I139 HydrophobicContact CE-CD1 3.66Å; M135-I139 HydrophobicContact CE-CG1 3.72Å; M135-I139 WeakPolarHBondContact O-CG1 3.4Å; M135-I139 PolarHBondContact O-N 3.01Å; M135-I139 VanDerWaalsContact O-N 3.12Å; R136-I139 PolarHBondContact O-N 3.47Å; I139-S141 VanDerWaalsContact C-N 3.34Å; I139-T145 HydrophobicContact CD1-CG2 4.13Å; I139-V148 HydrophobicContact CD1-CG2 4.35Å
140	N	82.3	Confident	84.8	Confident	128 Å²	128	50.1 Å²	50.1	68%	0.684	27%	0.266	S	S	*	.	H	α-helix	trans	-80.4	-12.4	179.9	-68.1	-17.2	0	0	0	113.8	R136 Q137 L138 G142	R136-N140 VanDerWaalsContact O-CB 3.3Å; R136-N140 WeakPolarHBondContact O-CB 3.27Å; R136-N140 PolarHBondContact O-N 2.82Å; R136-N140 PolarHBondContact O-ND2 2.7Å; Q137-N140 CarbonylContact O-C 3.55Å; Q137-N140 PolarHBondContact O-N 3.3Å; L138-N140 VanDerWaalsContact C-N 3.32Å; N140-G142 PolarHBondContact O-N 3.12Å
141	S	80	Confident	84.8	Confident	31 Å²	31	48.2 Å²	48.2	22%	0.217	26%	0.255	C	S	.	.	T	Hydrogen-bonded Turn	trans	-80.6	1.8	178.9	66.9	0	0	0	0	113.5	V94 Q137 L138 I139	V94-S141 WeakPolarHBondContact CG2-OG 3.49Å; Q137-S141 WeakPolarHBondContact O-CB 3.34Å; Q137-S141 PolarHBondContact O-N 3.4Å; L138-S141 PolarHBondContact O-N 3.11Å; L138-S141 PolarHBondContact O-OG 2.89Å; I139-S141 VanDerWaalsContact C-N 3.34Å
142	G	76.4	Confident	84.7	Confident	49 Å²	49	48.2 Å²	48.2	51%	0.505	26%	0.255	S	S	.	.	T	Hydrogen-bonded Turn	trans	93.7	0.7	179	0	0	0	0	0	114.8	F96 N140 E144	F96-G142 WeakPolarHBondContact CZ-O 2.88Å; N140-G142 PolarHBondContact O-N 3.12Å; G142-E144 PolarHBondContact O-N 3.42Å
143	I	79.7	Confident	84.6	Confident	10 Å²	10	49.9 Å²	49.9	5%	0.051	26%	0.262	C	S	.	.			trans	-68.9	129.2	172.9	-59.4	163.8	0	0	0	108.3	V94 F96 W103 L138 T145 V148	V94-I143 HydrophobicContact CG1-CD1 4.47Å; V94-I143 HydrophobicContact CG1-CG1 3.98Å; V94-I143 HydrophobicContact CG2-CD1 4.02Å; V94-I143 HydrophobicContact CG2-CG1 4.33Å; F96-I143 HydrophobicContact CZ-CG1 4.37Å; W103-I143 HydrophobicContact CB-CD1 3.55Å; W103-I143 HydrophobicContact CB-CG1 4.26Å; W103-I143 HydrophobicContact CD2-CD1 4.24Å; W103-I143 HydrophobicContact CD2-CG2 4.14Å; W103-I143 HydrophobicContact CE3-CD1 4.29Å; W103-I143 HydrophobicContact CG-CD1 3.92Å; W103-I143 HydrophobicContact CG-CG1 4.42Å; W103-I143 HydrophobicContact CG-CG2 4.24Å; L138-I143 HydrophobicContact CD2-CD1 3.92Å; I143-T145 PolarHBondContact O-N 3.44Å; I143-V148 HydrophobicContact CG2-CG2 3.63Å
144	E	82	Confident	84.4	Confident	138 Å²	138	49.5 Å²	49.5	65%	0.645	26%	0.264	S	S	*	.			trans	-60.3	128	177.6	-66.5	-173.3	180	0	0	111	G142 A146 T147 V148	G142-E144 PolarHBondContact O-N 3.42Å; E144-A146 PolarHBondContact O-N 2.93Å; E144-A146 VanDerWaalsContact O-N 3.17Å; E144-T147 WeakPolarHBondContact O-CB 3.37Å; E144-T147 PolarHBondContact O-N 3.47Å; E144-V148 PolarHBondContact O-N 2.99Å
145	T	85.2	Confident	84.2	Confident	46 Å²	46	53.5 Å²	53.5	28%	0.282	28%	0.281	S	S	.	.	H	α-helix	trans	-56.1	-35.5	178.1	-54.4	0	0	0	0	112	I139 I143 T147 V148 I149 V202	I139-T145 HydrophobicContact CD1-CG2 4.13Å; I143-T145 PolarHBondContact O-N 3.44Å; T145-T147 PolarHBondContact O-N 3.14Å; T145-V148 PolarHBondContact O-N 3.47Å; T145-I149 HydrophobicContact CG2-CG1 4.33Å; T145-I149 VanDerWaalsContact O-CG1 3.29Å; T145-I149 WeakPolarHBondContact O-CG1 3.5Å; T145-I149 PolarHBondContact O-N 3.38Å; T145-V202 HydrophobicContact CG2-CB 4.24Å; T145-V202 HydrophobicContact CG2-CG1 3.82Å; T145-V202 HydrophobicContact CG2-CG2 3.58Å
146	A	84.7	Confident	83.9	Confident	66 Å²	66	53.6 Å²	53.6	55%	0.545	28%	0.281	S	S	.	.	H	α-helix	trans	-60.5	-44.5	177.9	0	0	0	0	0	111.9	E144 V148 I149 E150	E144-A146 PolarHBondContact O-N 2.93Å; E144-A146 VanDerWaalsContact O-N 3.17Å; A146-V148 VanDerWaalsContact C-N 3.35Å; A146-V148 PolarHBondContact O-N 2.82Å; A146-I149 PolarHBondContact O-N 3.49Å; A146-E150 WeakPolarHBondContact O-CB 3.41Å; A146-E150 PolarHBondContact O-N 2.85Å
147	T	83.4	Confident	84	Confident	54 Å²	54	48.8 Å²	48.8	33%	0.331	26%	0.263	S	S	.	.	H	α-helix	trans	-61.4	-42.1	178.2	-53.4	0	0	0	0	111.7	W103 E144 T145 E150 Y151	W103-T147 HydrophobicContact CZ2-CG2 3.98Å; E144-T147 WeakPolarHBondContact O-CB 3.37Å; E144-T147 PolarHBondContact O-N 3.47Å; T145-T147 PolarHBondContact O-N 3.14Å; T147-E150 PolarHBondContact O-N 3.13Å; T147-Y151 WeakPolarHBondContact O-CB 3.42Å; T147-Y151 PolarHBondContact O-N 3.33Å
148	V	86.1	Confident	84.1	Confident	0 Å²	0	48.2 Å²	48.2	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-64.6	-44.1	177.2	-176.2	0	0	0	0	111.7	W103 W109 M135 I139 I143 E144 T145 A146 C152	W103-V148 HydrophobicContact CE3-CG2 4.38Å; W103-V148 HydrophobicContact CH2-CB 4.09Å; W103-V148 HydrophobicContact CH2-CG1 4.11Å; W103-V148 HydrophobicContact CH2-CG2 3.97Å; W103-V148 HydrophobicContact CZ2-CG2 4.42Å; W103-V148 HydrophobicContact CZ3-CB 4.36Å; W103-V148 HydrophobicContact CZ3-CG1 4.12Å; W103-V148 HydrophobicContact CZ3-CG2 3.93Å; W109-V148 HydrophobicContact CE3-CG1 4.09Å; W109-V148 HydrophobicContact CH2-CG1 4.05Å; W109-V148 HydrophobicContact CZ3-CG1 3.54Å; M135-V148 HydrophobicContact CE-CG1 3.73Å; M135-V148 HydrophobicContact SD-CG1 4.42Å; I139-V148 HydrophobicContact CD1-CG2 4.35Å; I143-V148 HydrophobicContact CG2-CG2 3.63Å; E144-V148 PolarHBondContact O-N 2.99Å; T145-V148 PolarHBondContact O-N 3.47Å; A146-V148 VanDerWaalsContact C-N 3.35Å; A146-V148 PolarHBondContact O-N 2.82Å; V148-C152 VanDerWaalsContact O-CB 3.27Å; V148-C152 WeakPolarHBondContact O-CB 3.48Å; V148-C152 PolarHBondContact O-N 2.99Å
149	I	88.7	Confident	84	Confident	15 Å²	15	48.7 Å²	48.7	8%	0.077	26%	0.261	C	S	.	.	H	α-helix	trans	-65.6	-43.7	179.1	-67.7	-65.6	0	0	0	111.3	T145 A146 C152 E153 F199 V202 T206 M210	T145-I149 HydrophobicContact CG2-CG1 4.33Å; T145-I149 VanDerWaalsContact O-CG1 3.29Å; T145-I149 WeakPolarHBondContact O-CG1 3.5Å; T145-I149 PolarHBondContact O-N 3.38Å; A146-I149 PolarHBondContact O-N 3.49Å; I149-C152 PolarHBondContact O-N 2.82Å; I149-E153 PolarHBondContact O-N 3.09Å; I149-F199 HydrophobicContact CD1-CD1 3.9Å; I149-F199 HydrophobicContact CD1-CE1 3.71Å; I149-V202 HydrophobicContact CD1-CG1 4.05Å; I149-V202 HydrophobicContact CG1-CG1 4.28Å; I149-T206 HydrophobicContact CG1-CG2 4.18Å; I149-T206 HydrophobicContact CG2-CG2 4.03Å; I149-M210 HydrophobicContact CD1-CE 4.21Å; I149-M210 HydrophobicContact CD1-SD 3.95Å; I149-M210 HydrophobicContact CG2-CB 4.38Å; I149-M210 HydrophobicContact CG2-CG 4.37Å; I149-M210 HydrophobicContact CG2-SD 3.91Å
150	E	85.3	Confident	84.1	Confident	98 Å²	98	47.4 Å²	47.4	46%	0.458	25%	0.254	S	S	.	.	H	α-helix	trans	-62.8	-44.9	178.1	-178.1	176.8	175.3	0	0	111.7	A146 T147 E153 K154	A146-E150 WeakPolarHBondContact O-CB 3.41Å; A146-E150 PolarHBondContact O-N 2.85Å; T147-E150 PolarHBondContact O-N 3.13Å; E150-E153 PolarHBondContact O-N 2.93Å; E150-K154 HydrophobicContact CG-CD 3.87Å; E150-K154 HydrophobicContact CG-CG 4.4Å; E150-K154 WeakPolarHBondContact O-CB 3.36Å; E150-K154 WeakPolarHBondContact O-CG 3.42Å; E150-K154 PolarHBondContact O-N 3.44Å; E150-K154 WeakPolarHBondContact OE1-CE 3.24Å; E150-K154 IonicContact OE1-NZ 2.92Å; E150-K154 PolarHBondContact OE1-NZ 3.46Å
151	Y	85	Confident	84.3	Confident	50 Å²	50	41.3 Å²	41.3	20%	0.196	22%	0.222	C	C	.	.	H	α-helix	trans	-61.9	-46.3	175.6	-175.7	-81.7	0	0	0	111.1	W103 S104 W109 T147 E153 K154 K155 V156	W103-Y151 HydrophobicContact CH2-CD1 4.14Å; W103-Y151 AromaticContact CH2-CG 3.88Å; W103-Y151 HydrophobicContact CH2-CG 3.88Å; W103-Y151 HydrophobicContact CZ2-CD2 4.32Å; W103-Y151 HydrophobicContact CZ2-CG 4Å; S104-Y151 VanDerWaalsContact CB-CE2 3.44Å; S104-Y151 VanDerWaalsContact CB-CZ 3.5Å; W109-Y151 AromaticContact CE2-CD1 3.89Å; W109-Y151 AromaticContact CE2-CE1 3.93Å; W109-Y151 AromaticContact CZ2-CD1 3.64Å; W109-Y151 HydrophobicContact CZ2-CD1 3.64Å; W109-Y151 AromaticContact CZ2-CE1 3.98Å; W109-Y151 HydrophobicContact CZ2-CE1 3.98Å; W109-Y151 AromaticContact NE1-CD1 3.81Å; W109-Y151 AromaticContact NE1-CE1 3.4Å; T147-Y151 WeakPolarHBondContact O-CB 3.42Å; T147-Y151 PolarHBondContact O-N 3.33Å; Y151-E153 VanDerWaalsContact C-N 3.32Å; Y151-E153 PolarHBondContact O-N 2.86Å; Y151-K154 PolarHBondContact O-N 3.38Å; Y151-K155 HydrophobicContact CD1-CB 4.39Å; Y151-K155 HydrophobicContact CD2-CG 4.28Å; Y151-K155 HydrophobicContact CE1-CB 4.05Å; Y151-K155 HydrophobicContact CE1-CG 4.47Å; Y151-K155 HydrophobicContact CE2-CB 4.46Å; Y151-K155 HydrophobicContact CE2-CG 4Å; Y151-K155 WeakPolarHBondContact O-CB 3.29Å; Y151-K155 PolarHBondContact O-N 3.27Å; Y151-V156 HydrophobicContact CD1-CG2 4.35Å; Y151-V156 HydrophobicContact CE1-CG2 4.1Å
152	C	88.2	Confident	84.5	Confident	0 Å²	0	42.2 Å²	42.2	0%	0	22%	0.22	C	C	.	.	I	π-helix	trans	-57.7	-44.2	177.6	-170.5	0	0	0	0	111.5	W109 V148 I149 V156 L157 M210	W109-C152 HydrophobicContact CH2-CB 3.96Å; W109-C152 HydrophobicContact CZ2-CB 4.47Å; V148-C152 VanDerWaalsContact O-CB 3.27Å; V148-C152 WeakPolarHBondContact O-CB 3.48Å; V148-C152 PolarHBondContact O-N 2.99Å; I149-C152 PolarHBondContact O-N 2.82Å; C152-V156 WeakPolarHBondContact O-CB 3.32Å; C152-V156 PolarHBondContact O-N 3.3Å; C152-L157 WeakPolarHBondContact O-CB 3.5Å; C152-L157 WeakPolarHBondContact O-CG 3.39Å; C152-L157 PolarHBondContact O-N 3.21Å; C152-M210 HydrophobicContact CB-SD 3.81Å
153	E	86.4	Confident	84.7	Confident	36 Å²	36	40.2 Å²	40.2	17%	0.168	20%	0.198	C	C	.	.	I	π-helix	trans	-64.1	-53.2	176.5	-169.2	-173	148	0	0	112	I149 E150 Y151 R158 M210 V213	I149-E153 PolarHBondContact O-N 3.09Å; E150-E153 PolarHBondContact O-N 2.93Å; Y151-E153 VanDerWaalsContact C-N 3.32Å; Y151-E153 PolarHBondContact O-N 2.86Å; E153-R158 PolarHBondContact O-N 2.71Å; E153-M210 HydrophobicContact CB-CG 4.07Å; E153-M210 HydrophobicContact CG-CG 4.44Å; E153-V213 HydrophobicContact CG-CG1 4.44Å
154	K	84	Confident	84.9	Confident	109 Å²	109	40 Å²	40	47%	0.474	20%	0.197	S	C	.	.	I	π-helix	trans	-76.8	-28.5	-168	-71.6	-175.7	176.7	178.9	0	114.1	E150 Y151 R158	E150-K154 HydrophobicContact CG-CD 3.87Å; E150-K154 HydrophobicContact CG-CG 4.4Å; E150-K154 WeakPolarHBondContact O-CB 3.36Å; E150-K154 WeakPolarHBondContact O-CG 3.42Å; E150-K154 PolarHBondContact O-N 3.44Å; E150-K154 WeakPolarHBondContact OE1-CE 3.24Å; E150-K154 IonicContact OE1-NZ 2.92Å; E150-K154 PolarHBondContact OE1-NZ 3.46Å; Y151-K154 PolarHBondContact O-N 3.38Å; K154-R158 VanDerWaalsContact O-CB 3.28Å; K154-R158 WeakPolarHBondContact O-CB 3.46Å; K154-R158 VanDerWaalsContact O-CD 3.3Å; K154-R158 WeakPolarHBondContact O-CD 3.21Å
155	K	82.1	Confident	85.1	Confident	90 Å²	90	34.9 Å²	34.9	39%	0.391	17%	0.172	S	C	.	.	I	π-helix	trans	-111.2	-65.2	-176.6	-64.4	-72.5	-170.3	164.1	0	111.2	Y151 N159	Y151-K155 HydrophobicContact CD1-CB 4.39Å; Y151-K155 HydrophobicContact CD2-CG 4.28Å; Y151-K155 HydrophobicContact CE1-CB 4.05Å; Y151-K155 HydrophobicContact CE1-CG 4.47Å; Y151-K155 HydrophobicContact CE2-CB 4.46Å; Y151-K155 HydrophobicContact CE2-CG 4Å; Y151-K155 WeakPolarHBondContact O-CB 3.29Å; Y151-K155 PolarHBondContact O-N 3.27Å; K155-N159 WeakPolarHBondContact O-CB 3.4Å; K155-N159 VanDerWaalsContact O-CG 3.3Å; K155-N159 PolarHBondContact O-N 3.47Å; K155-N159 VanDerWaalsContact O-N 3.09Å
156	V	84.7	Confident	85	Confident	1 Å²	1	35.8 Å²	35.8	1%	0.006	17%	0.17	C	C	.	.	I	π-helix	trans	-63.5	-63.2	-172.6	-176.9	0	0	0	0	110.7	W109 Q113 I116 I117 Y151 C152 R158 N159 T160	W109-V156 HydrophobicContact CZ2-CG2 3.81Å; Q113-V156 HydrophobicContact CB-CG1 4.39Å; Q113-V156 HydrophobicContact CB-CG2 3.95Å; I116-V156 HydrophobicContact CG2-CG1 4.15Å; I117-V156 HydrophobicContact CD1-CG1 4.16Å; I117-V156 HydrophobicContact CG1-CG1 3.8Å; Y151-V156 HydrophobicContact CD1-CG2 4.35Å; Y151-V156 HydrophobicContact CE1-CG2 4.1Å; C152-V156 WeakPolarHBondContact O-CB 3.32Å; C152-V156 PolarHBondContact O-N 3.3Å; V156-R158 PolarHBondContact O-N 3.5Å; V156-N159 PolarHBondContact O-N 2.89Å; V156-T160 PolarHBondContact O-N 3.37Å; V156-T160 PolarHBondContact O-OG1 2.83Å
157	L	89.4	Confident	84.8	Confident	0 Å²	0	34 Å²	34	0%	0	15%	0.153	C	C	.	.	I	π-helix	trans	-64.7	-39.6	-176.5	-65.2	177.8	0	0	0	112	I116 I120 C152 N159 T160 M161 M210 L211 S214	I116-L157 HydrophobicContact CG2-CD2 4.22Å; I120-L157 HydrophobicContact CD1-CD2 3.49Å; I120-L157 VanDerWaalsContact CD1-CD2 3.49Å; C152-L157 WeakPolarHBondContact O-CB 3.5Å; C152-L157 WeakPolarHBondContact O-CG 3.39Å; C152-L157 PolarHBondContact O-N 3.21Å; L157-N159 PolarHBondContact O-N 3.32Å; L157-T160 PolarHBondContact O-N 2.82Å; L157-M161 WeakPolarHBondContact O-CB 3.48Å; L157-M161 WeakPolarHBondContact O-CG 3.27Å; L157-M161 PolarHBondContact O-N 3.22Å; L157-M210 HydrophobicContact CD1-CE 4.07Å; L157-M210 HydrophobicContact CD1-CG 3.56Å; L157-M210 HydrophobicContact CD1-SD 3.9Å; L157-L211 HydrophobicContact CD1-CD2 4.06Å; L157-L211 HydrophobicContact CD2-CD2 4.11Å; L157-S214 WeakPolarHBondContact CB-OG 3.33Å; L157-S214 WeakPolarHBondContact CD1-OG 3.47Å
158	R	85.4	Confident	85.1	Confident	59 Å²	59	31.5 Å²	31.5	22%	0.223	14%	0.137	C	C	.	.	H	α-helix	trans	-51.3	-53.7	172.8	176.8	180	176.9	-175.5	-2.7	111.6	E73 E153 K154 V156 R162 Y218	E73-R158 IonicContact OE1-NH2 3.57Å; E153-R158 PolarHBondContact O-N 2.71Å; K154-R158 VanDerWaalsContact O-CB 3.28Å; K154-R158 WeakPolarHBondContact O-CB 3.46Å; K154-R158 VanDerWaalsContact O-CD 3.3Å; K154-R158 WeakPolarHBondContact O-CD 3.21Å; V156-R158 PolarHBondContact O-N 3.5Å; R158-R162 WeakPolarHBondContact O-CB 3.46Å; R158-R162 PolarHBondContact O-N 2.8Å; R158-R162 VanDerWaalsContact O-N 3.1Å; R158-Y218 HydrophobicContact CB-CD2 4.39Å; R158-Y218 HydrophobicContact CB-CE1 4.06Å; R158-Y218 HydrophobicContact CB-CE2 3.87Å; R158-Y218 HydrophobicContact CG-CD1 4.11Å; R158-Y218 HydrophobicContact CG-CE1 3.62Å; R158-Y218 HydrophobicContact CG-CE2 4.37Å
159	N	83.2	Confident	85.1	Confident	16 Å²	16	36.4 Å²	36.4	9%	0.086	16%	0.16	C	C	.	.	H	α-helix	trans	-71.9	-40.6	-174.5	-69.6	-3.8	0	0	0	111.3	L61 K155 V156 L157 R162 T163	L61-N159 PolarHBondContact O-ND2 3.29Å; K155-N159 WeakPolarHBondContact O-CB 3.4Å; K155-N159 VanDerWaalsContact O-CG 3.3Å; K155-N159 PolarHBondContact O-N 3.47Å; K155-N159 VanDerWaalsContact O-N 3.09Å; V156-N159 PolarHBondContact O-N 2.89Å; L157-N159 PolarHBondContact O-N 3.32Å; N159-R162 WeakPolarHBondContact O-CB 3.26Å; N159-R162 PolarHBondContact O-N 3.42Å; N159-T163 PolarHBondContact O-N 3.09Å; N159-T163 VanDerWaalsContact O-N 3.09Å; N159-T163 PolarHBondContact O-OG1 2.91Å
160	T	83.9	Confident	85.1	Confident	0 Å²	0	43.7 Å²	43.7	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-66.4	-44	178.2	-43.5	0	0	0	0	112.4	I117 I120 L121 V156 L157 R162 T163 L164	I117-T160 WeakPolarHBondContact CG1-OG1 3.4Å; I117-T160 HydrophobicContact CG2-CG2 4.36Å; I120-T160 HydrophobicContact CB-CG2 3.7Å; I120-T160 HydrophobicContact CD1-CG2 4.2Å; I120-T160 HydrophobicContact CG2-CG2 3.53Å; L121-T160 HydrophobicContact CD1-CG2 4.2Å; L121-T160 HydrophobicContact CD2-CG2 3.85Å; L121-T160 HydrophobicContact CG-CG2 3.74Å; V156-T160 PolarHBondContact O-N 3.37Å; V156-T160 PolarHBondContact O-OG1 2.83Å; L157-T160 PolarHBondContact O-N 2.82Å; T160-R162 VanDerWaalsContact C-N 3.3Å; T160-R162 PolarHBondContact O-N 2.84Å; T160-T163 WeakPolarHBondContact O-CB 3.25Å; T160-T163 PolarHBondContact O-N 3.16Å; T160-L164 PolarHBondContact O-N 2.91Å
161	M	87.7	Confident	85.3	Confident	0 Å²	0	40.5 Å²	40.5	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-64.8	-36.1	177.5	-68.3	-64.6	179.5	0	0	111.8	L157 T163 L164 R165 Y187 F215 Y218 I219	L157-M161 WeakPolarHBondContact O-CB 3.48Å; L157-M161 WeakPolarHBondContact O-CG 3.27Å; L157-M161 PolarHBondContact O-N 3.22Å; M161-T163 VanDerWaalsContact C-N 3.34Å; M161-L164 PolarHBondContact O-N 2.86Å; M161-L164 HydrophobicContact SD-CD2 4.3Å; M161-R165 WeakPolarHBondContact O-CB 3.23Å; M161-R165 PolarHBondContact O-N 2.71Å; M161-Y187 HydrophobicContact CE-CD2 4.34Å; M161-Y187 HydrophobicContact CE-CE2 3.45Å; M161-Y187 VanDerWaalsContact CE-CE2 3.45Å; M161-Y187 WeakPolarHBondContact CE-OH 3.29Å; M161-F215 HydrophobicContact CE-CB 4.35Å; M161-F215 HydrophobicContact CE-CD2 4.3Å; M161-F215 HydrophobicContact SD-CD2 4.17Å; M161-Y218 HydrophobicContact CB-CG 4.43Å; M161-I219 HydrophobicContact CB-CD1 4.45Å; M161-I219 HydrophobicContact CB-CG1 4.2Å; M161-I219 HydrophobicContact SD-CD1 3.69Å; M161-I219 HydrophobicContact SD-CG1 4.27Å
162	R	82.6	Confident	85.4	Confident	50 Å²	50	44.2 Å²	44.2	19%	0.189	20%	0.201	C	C	.	.	H	α-helix	trans	-60.8	-44.6	172.9	-177.3	-178	-178.1	161.8	3.9	111.4	E73 R158 N159 T160 L164 R165 R166	E73-R162 VanDerWaalsContact CD-NH1 3.31Å; E73-R162 IonicContact OE1-NH1 3.3Å; E73-R162 PolarHBondContact OE1-NH1 3.24Å; E73-R162 IonicContact OE2-CZ 2.6Å; E73-R162 IonicContact OE2-NH1 2.65Å; E73-R162 PolarHBondContact OE2-NH1 3.34Å; E73-R162 IonicContact OE2-NH2 3.21Å; E73-R162 PolarHBondContact OE2-NH2 2.98Å; R158-R162 WeakPolarHBondContact O-CB 3.46Å; R158-R162 PolarHBondContact O-N 2.8Å; R158-R162 VanDerWaalsContact O-N 3.1Å; N159-R162 WeakPolarHBondContact O-CB 3.26Å; N159-R162 PolarHBondContact O-N 3.42Å; T160-R162 VanDerWaalsContact C-N 3.3Å; T160-R162 PolarHBondContact O-N 2.84Å; R162-L164 VanDerWaalsContact C-N 3.34Å; R162-R165 WeakPolarHBondContact O-CB 3.41Å; R162-R165 PolarHBondContact O-N 3.18Å; R162-R165 VanDerWaalsContact O-N 3.16Å; R162-R166 PolarHBondContact O-N 3.41Å; R162-R166 VanDerWaalsContact O-N 3.09Å
163	T	81.4	Confident	85.2	Confident	7 Å²	7	45.7 Å²	45.7	4%	0.043	22%	0.216	C	C	.	.	H	α-helix	trans	-64.1	-39.9	177	-67.6	0	0	0	0	112.1	Y55 L61 L121 N159 T160 M161 R165 P167	Y55-T163 HydrophobicContact CD1-CG2 3.44Å; Y55-T163 VanDerWaalsContact CD1-CG2 3.44Å; Y55-T163 HydrophobicContact CE1-CG2 4.02Å; Y55-T163 HydrophobicContact CG-CG2 4.42Å; L61-T163 HydrophobicContact CD2-CG2 4.24Å; L61-T163 WeakPolarHBondContact CD2-OG1 3.3Å; L121-T163 HydrophobicContact CD1-CG2 4.28Å; L121-T163 HydrophobicContact CD2-CG2 3.92Å; N159-T163 PolarHBondContact O-N 3.09Å; N159-T163 VanDerWaalsContact O-N 3.09Å; N159-T163 PolarHBondContact O-OG1 2.91Å; T160-T163 WeakPolarHBondContact O-CB 3.25Å; T160-T163 PolarHBondContact O-N 3.16Å; M161-T163 VanDerWaalsContact C-N 3.34Å; T163-R165 VanDerWaalsContact C-N 3.27Å; T163-R165 PolarHBondContact O-N 3.4Å; T163-P167 WeakPolarHBondContact O-CD 3.48Å
164	L	83.6	Confident	85.1	Confident	6 Å²	6	49 Å²	49	3%	0.031	24%	0.235	C	C	.	.	H	α-helix	trans	-65.1	-30.4	173.6	-170.8	59	0	0	0	112.6	I120 T160 M161 R162 P167 I183 I219	I120-L164 HydrophobicContact CG2-CD2 4.04Å; T160-L164 PolarHBondContact O-N 2.91Å; M161-L164 PolarHBondContact O-N 2.86Å; M161-L164 HydrophobicContact SD-CD2 4.3Å; R162-L164 VanDerWaalsContact C-N 3.34Å; L164-P167 WeakPolarHBondContact O-CD 3.46Å; L164-I183 HydrophobicContact CD1-CD1 4.02Å; L164-I183 HydrophobicContact CD1-CG1 4.07Å; L164-I183 HydrophobicContact CD1-CG2 3.92Å; L164-I183 HydrophobicContact CD2-CG2 3.59Å; L164-I183 HydrophobicContact CG-CD1 4.23Å; L164-I183 HydrophobicContact CG-CG2 3.72Å; L164-I219 HydrophobicContact CD2-CD1 3.96Å; L164-I219 HydrophobicContact CG-CD1 4.31Å
165	R	86.3	Confident	85.2	Confident	30 Å²	30	49.6 Å²	49.6	11%	0.113	24%	0.239	C	C	.	.	H	α-helix	trans	-78.5	-35.5	179.9	-170.9	-174.2	70.5	-149.9	6.9	114.1	M161 R162 T163 P167 L168 E169 Y218 M223	M161-R165 WeakPolarHBondContact O-CB 3.23Å; M161-R165 PolarHBondContact O-N 2.71Å; R162-R165 WeakPolarHBondContact O-CB 3.41Å; R162-R165 PolarHBondContact O-N 3.18Å; R162-R165 VanDerWaalsContact O-N 3.16Å; T163-R165 VanDerWaalsContact C-N 3.27Å; T163-R165 PolarHBondContact O-N 3.4Å; R165-P167 VanDerWaalsContact C-N 3.31Å; R165-P167 VanDerWaalsContact O-N 3.12Å; R165-L168 WeakPolarHBondContact O-CA 3.39Å; R165-L168 VanDerWaalsContact O-CB 3.23Å; R165-L168 WeakPolarHBondContact O-CB 3.29Å; R165-L168 PolarHBondContact O-N 3.34Å; R165-E169 HydrophobicContact CG-CG 4.18Å; R165-E169 IonicContact CZ-OE1 3.2Å; R165-E169 IonicContact NE-OE1 2.71Å; R165-E169 PolarHBondContact NE-OE1 3.21Å; R165-E169 IonicContact NH2-OE1 2.84Å; R165-E169 PolarHBondContact NH2-OE1 3.43Å; R165-E169 PolarHBondContact O-N 3.21Å; R165-Y218 VanDerWaalsContact CD-O 3.29Å; R165-Y218 WeakPolarHBondContact CD-O 3.25Å; R165-Y218 PolarHBondContact NH1-O 3.03Å; R165-M223 HydrophobicContact CG-CG 3.64Å; R165-M223 HydrophobicContact CG-SD 3.74Å
166	R	83.3	Confident	85.6	Confident	65 Å²	65	45.5 Å²	45.5	25%	0.245	22%	0.222	C	C	.	.	T	Hydrogen-bonded Turn	trans	-46.3	-43.3	-175	-79.4	-178	-179.8	164.9	7.9	115.3	R162 L168 E169	R162-R166 PolarHBondContact O-N 3.41Å; R162-R166 VanDerWaalsContact O-N 3.09Å; R166-L168 VanDerWaalsContact C-N 3.27Å; R166-L168 PolarHBondContact O-N 3.39Å; R166-E169 PolarHBondContact O-N 3.15Å
167	P	80.7	Confident	85.8	Confident	27 Å²	27	46 Å²	46	18%	0.175	22%	0.224	C	C	.	.	T	Hydrogen-bonded Turn	trans	-64.4	-34.9	178.3	-21.2	34.9	0	0	0	112.5	V51 T163 L164 R165 E169 K170	V51-P167 HydrophobicContact CB-CB 4.29Å; V51-P167 HydrophobicContact CG1-CB 3.25Å; V51-P167 HydrophobicContact CG1-CG 3.14Å; V51-P167 HydrophobicContact CG2-CB 4.06Å; T163-P167 WeakPolarHBondContact O-CD 3.48Å; L164-P167 WeakPolarHBondContact O-CD 3.46Å; R165-P167 VanDerWaalsContact C-N 3.31Å; R165-P167 VanDerWaalsContact O-N 3.12Å; P167-E169 VanDerWaalsContact C-N 3.34Å; P167-K170 PolarHBondContact O-N 3.38Å
168	L	88.7	Confident	85.7	Confident	2 Å²	2	49.4 Å²	49.4	1%	0.01	25%	0.248	C	C	.	.	G	3₁₀ helix	trans	-70	-30.7	179.5	-55.4	179.3	0	0	0	112.3	R165 R166 K170 L171 L176 E179 L180 I183 I219 M223	R165-L168 WeakPolarHBondContact O-CA 3.39Å; R165-L168 VanDerWaalsContact O-CB 3.23Å; R165-L168 WeakPolarHBondContact O-CB 3.29Å; R165-L168 PolarHBondContact O-N 3.34Å; R166-L168 VanDerWaalsContact C-N 3.27Å; R166-L168 PolarHBondContact O-N 3.39Å; L168-K170 PolarHBondContact O-N 3.43Å; L168-K170 VanDerWaalsContact O-N 3.09Å; L168-L171 HydrophobicContact CD2-CD1 4.35Å; L168-L171 PolarHBondContact O-N 2.91Å; L168-L176 HydrophobicContact CB-CD1 3.69Å; L168-L176 HydrophobicContact CD2-CD1 4.21Å; L168-L176 HydrophobicContact CG-CD1 4.42Å; L168-E179 HydrophobicContact CD2-CB 3.56Å; L168-L180 HydrophobicContact CD1-CD1 4.05Å; L168-I183 HydrophobicContact CD1-CD1 3.77Å; L168-I183 HydrophobicContact CD2-CD1 3.73Å; L168-I183 HydrophobicContact CG-CD1 3.82Å; L168-I219 HydrophobicContact CD1-CG2 4.24Å; L168-M223 HydrophobicContact CB-CE 3.48Å; L168-M223 VanDerWaalsContact CB-CE 3.48Å; L168-M223 HydrophobicContact CB-SD 3.46Å; L168-M223 WeakPolarHBondContact CB-SD 3.42Å; L168-M223 HydrophobicContact CD1-SD 3.58Å; L168-M223 VanDerWaalsContact CD1-SD 3.58Å; L168-M223 HydrophobicContact CG-SD 4.2Å; L168-M223 WeakPolarHBondContact O-CE 2.99Å
169	E	87.3	Confident	85.9	Confident	103 Å²	103	49.5 Å²	49.5	48%	0.481	25%	0.251	S	S	.	.	G	3₁₀ helix	trans	-61.3	-19.5	-179.5	-66.4	173.4	165	0	0	113.1	R165 R166 P167	R165-E169 HydrophobicContact CG-CG 4.18Å; R165-E169 IonicContact CZ-OE1 3.2Å; R165-E169 IonicContact NE-OE1 2.71Å; R165-E169 PolarHBondContact NE-OE1 3.21Å; R165-E169 IonicContact NH2-OE1 2.84Å; R165-E169 PolarHBondContact NH2-OE1 3.43Å; R165-E169 PolarHBondContact O-N 3.21Å; R166-E169 PolarHBondContact O-N 3.15Å; P167-E169 VanDerWaalsContact C-N 3.34Å
170	K	88	Confident	86.3	Confident	168 Å²	168	48.8 Å²	48.8	73%	0.73	25%	0.247	S	C	*	.	G	3₁₀ helix	trans	-87.5	-10.5	177.2	-60.1	178.6	-177.2	176.3	0	113.3	P167 L168	P167-K170 PolarHBondContact O-N 3.38Å; L168-K170 PolarHBondContact O-N 3.43Å; L168-K170 VanDerWaalsContact O-N 3.09Å
171	L	89.8	Confident	86.4	Confident	32 Å²	32	49.5 Å²	49.5	17%	0.168	25%	0.251	C	S	.	.			trans	-104	156	-172.9	-53.4	178	0	0	0	110.7	L168 E175 L176 E179	L168-L171 HydrophobicContact CD2-CD1 4.35Å; L168-L171 PolarHBondContact O-N 2.91Å; L171-E175 HydrophobicContact CD1-CG 4.47Å; L171-E175 HydrophobicContact CD2-CG 4.12Å; L171-L176 HydrophobicContact CB-CB 3.84Å; L171-L176 HydrophobicContact CB-CD1 4.35Å; L171-E179 HydrophobicContact CD1-CB 3.76Å; L171-E179 HydrophobicContact CD1-CG 3.45Å; L171-E179 VanDerWaalsContact CD1-CG 3.45Å
172	N	86.1	Confident	86.3	Confident	127 Å²	127	51.3 Å²	51.3	68%	0.679	27%	0.269	S	S	*	.			trans	-138.8	157.5	177.8	-76.4	-63.8	0	0	0	112.2	N174 E175	N172-N174 PolarHBondContact O-N 3.03Å; N172-E175 PolarHBondContact O-N 3.16Å
173	G	84.4	Confident	86.6	Confident	31 Å²	31	49.7 Å²	49.7	32%	0.32	27%	0.265	S	S	.	.	H	α-helix	trans	58.7	-129.2	171.9	0	0	0	0	0	113.6	I177	G173-I177 WeakPolarHBondContact O-CG1 3.33Å; G173-I177 PolarHBondContact O-N 3.45Å
174	N	84.1	Confident	86.9	Confident	105 Å²	105	49.6 Å²	49.6	56%	0.561	26%	0.263	S	S	*	.	H	α-helix	trans	-69.1	-34.9	-174.5	-69.7	-15.9	0	0	0	113.4	N172 I177 S178 Q232	N172-N174 PolarHBondContact O-N 3.03Å; N174-I177 PolarHBondContact O-N 2.84Å; N174-S178 PolarHBondContact O-N 3.06Å; N174-Q232 PolarHBondContact OD1-NE2 3.12Å
175	E	87.5	Confident	86.9	Confident	123 Å²	123	53.4 Å²	53.4	58%	0.575	28%	0.28	S	S	*	.	H	α-helix	trans	-63.7	-46.5	179.4	-172.2	177.8	-166.1	0	0	110.5	L171 N172 I177 S178 E179	L171-E175 HydrophobicContact CD1-CG 4.47Å; L171-E175 HydrophobicContact CD2-CG 4.12Å; N172-E175 PolarHBondContact O-N 3.16Å; E175-I177 VanDerWaalsContact C-N 3.33Å; E175-I177 PolarHBondContact O-N 3.29Å; E175-S178 WeakPolarHBondContact O-CB 3.36Å; E175-S178 PolarHBondContact O-N 3.36Å; E175-S178 VanDerWaalsContact O-N 3.15Å; E175-E179 PolarHBondContact O-N 3.16Å
176	L	90.6	Very high	86.8	Confident	3 Å²	3	55.3 Å²	55.3	2%	0.016	29%	0.287	C	S	.	.	H	α-helix	trans	-55.7	-46.6	172.9	170.2	58.1	0	0	0	112.4	L168 L171 S178 E179 L180 M223 I225 I228	L168-L176 HydrophobicContact CB-CD1 3.69Å; L168-L176 HydrophobicContact CD2-CD1 4.21Å; L168-L176 HydrophobicContact CG-CD1 4.42Å; L171-L176 HydrophobicContact CB-CB 3.84Å; L171-L176 HydrophobicContact CB-CD1 4.35Å; L176-S178 VanDerWaalsContact C-N 3.32Å; L176-S178 PolarHBondContact O-N 2.77Å; L176-E179 PolarHBondContact O-N 2.95Å; L176-L180 VanDerWaalsContact O-CB 3.25Å; L176-L180 WeakPolarHBondContact O-CB 3.33Å; L176-L180 PolarHBondContact O-N 2.97Å; L176-M223 HydrophobicContact CD1-CE 3.3Å; L176-M223 HydrophobicContact CD1-SD 4.11Å; L176-M223 HydrophobicContact CD2-CE 3.89Å; L176-M223 HydrophobicContact CG-CE 4.23Å; L176-I225 HydrophobicContact CD2-CD1 4.14Å; L176-I225 HydrophobicContact CG-CD1 4.38Å; L176-I228 HydrophobicContact CD2-CD1 3.37Å
177	I	88.7	Confident	87	Confident	12 Å²	12	52.5 Å²	52.5	6%	0.062	28%	0.277	C	S	.	.	H	α-helix	trans	-64.9	-38.4	179.4	-65.4	-61.3	0	0	0	111.2	G173 N174 E175 I181 I225 I228 I229 V240	G173-I177 WeakPolarHBondContact O-CG1 3.33Å; G173-I177 PolarHBondContact O-N 3.45Å; N174-I177 PolarHBondContact O-N 2.84Å; E175-I177 VanDerWaalsContact C-N 3.33Å; E175-I177 PolarHBondContact O-N 3.29Å; I177-I181 HydrophobicContact CG2-CD1 3.88Å; I177-I181 HydrophobicContact CG2-CG1 4.49Å; I177-I181 WeakPolarHBondContact O-CD1 3.32Å; I177-I181 WeakPolarHBondContact O-CG1 3.14Å; I177-I181 PolarHBondContact O-N 3.37Å; I177-I225 HydrophobicContact CD1-CG2 4.11Å; I177-I228 HydrophobicContact CD1-CG2 4.21Å; I177-I228 HydrophobicContact CG1-CG2 4.24Å; I177-I229 HydrophobicContact CD1-CG1 4.4Å; I177-V240 HydrophobicContact CG2-CG2 3.87Å
178	S	86.5	Confident	87.2	Confident	72 Å²	72	51.8 Å²	51.8	50%	0.503	27%	0.271	S	S	.	.	H	α-helix	trans	-62.5	-49.2	177.2	-169.3	0	0	0	0	111.7	N174 E175 L176 I181 G182	N174-S178 PolarHBondContact O-N 3.06Å; E175-S178 WeakPolarHBondContact O-CB 3.36Å; E175-S178 PolarHBondContact O-N 3.36Å; E175-S178 VanDerWaalsContact O-N 3.15Å; L176-S178 VanDerWaalsContact C-N 3.32Å; L176-S178 PolarHBondContact O-N 2.77Å; S178-I181 WeakPolarHBondContact O-CB 3.3Å; S178-I181 PolarHBondContact O-N 3.26Å; S178-G182 PolarHBondContact O-N 3.37Å; S178-G182 VanDerWaalsContact O-N 3.08Å
179	E	88.7	Confident	86.8	Confident	60 Å²	60	56.9 Å²	56.9	28%	0.28	30%	0.298	S	S	.	.	H	α-helix	trans	-66.1	-39.5	178.6	-69.6	-54.9	131.3	0	0	112.2	L168 L171 E175 L176 I181 G182 I183	L168-E179 HydrophobicContact CD2-CB 3.56Å; L171-E179 HydrophobicContact CD1-CB 3.76Å; L171-E179 HydrophobicContact CD1-CG 3.45Å; L171-E179 VanDerWaalsContact CD1-CG 3.45Å; E175-E179 PolarHBondContact O-N 3.16Å; L176-E179 PolarHBondContact O-N 2.95Å; E179-I181 VanDerWaalsContact C-N 3.28Å; E179-I181 PolarHBondContact O-N 2.99Å; E179-G182 PolarHBondContact O-N 3.43Å; E179-G182 VanDerWaalsContact O-N 3.12Å; E179-I183 PolarHBondContact O-N 3.01Å
180	L	92	Very high	86.5	Confident	1 Å²	1	55.9 Å²	55.9	1%	0.005	29%	0.291	C	S	.	.	H	α-helix	trans	-60.2	-38.6	173.5	178.9	63.8	0	0	0	111.9	L168 L176 I183 W184 F215 I219 L220 I225 M243	L168-L180 HydrophobicContact CD1-CD1 4.05Å; L176-L180 VanDerWaalsContact O-CB 3.25Å; L176-L180 WeakPolarHBondContact O-CB 3.33Å; L176-L180 PolarHBondContact O-N 2.97Å; L180-I183 PolarHBondContact O-N 3.11Å; L180-W184 VanDerWaalsContact O-CB 3.3Å; L180-W184 WeakPolarHBondContact O-CB 3.44Å; L180-W184 PolarHBondContact O-N 3.46Å; L180-F215 HydrophobicContact CD1-CE1 4.33Å; L180-F215 HydrophobicContact CD1-CZ 4.18Å; L180-I219 HydrophobicContact CD1-CG2 3.86Å; L180-L220 HydrophobicContact CD1-CD2 4.17Å; L180-L220 HydrophobicContact CD2-CD2 3.87Å; L180-I225 HydrophobicContact CD2-CB 4.49Å; L180-I225 HydrophobicContact CD2-CD1 3.76Å; L180-I225 HydrophobicContact CD2-CG1 3.8Å; L180-I225 HydrophobicContact CD2-CG2 3.87Å; L180-M243 HydrophobicContact CD2-CE 3.98Å; L180-M243 HydrophobicContact CG-CE 4.43Å; L180-M243 HydrophobicContact CG-SD 4.39Å
181	I	87	Confident	86.5	Confident	15 Å²	15	47.9 Å²	47.9	8%	0.077	26%	0.256	C	S	.	.	H	α-helix	trans	-65.1	-40.9	175.3	-71.9	162.6	0	0	0	110.8	I177 S178 E179 W184 K185 N237 H239 V240	I177-I181 HydrophobicContact CG2-CD1 3.88Å; I177-I181 HydrophobicContact CG2-CG1 4.49Å; I177-I181 WeakPolarHBondContact O-CD1 3.32Å; I177-I181 WeakPolarHBondContact O-CG1 3.14Å; I177-I181 PolarHBondContact O-N 3.37Å; S178-I181 WeakPolarHBondContact O-CB 3.3Å; S178-I181 PolarHBondContact O-N 3.26Å; E179-I181 VanDerWaalsContact C-N 3.28Å; E179-I181 PolarHBondContact O-N 2.99Å; I181-W184 PolarHBondContact O-N 3.25Å; I181-K185 HydrophobicContact CG2-CD 4.19Å; I181-K185 HydrophobicContact CG2-CG 4.39Å; I181-K185 WeakPolarHBondContact O-CB 3.48Å; I181-K185 WeakPolarHBondContact O-CG 3.3Å; I181-K185 PolarHBondContact O-N 3.41Å; I181-N237 HydrophobicContact CD1-CB 3.84Å; I181-H239 HydrophobicContact CB-CB 4.48Å; I181-H239 HydrophobicContact CD1-CB 4.32Å; I181-H239 HydrophobicContact CG1-CB 4.05Å; I181-H239 HydrophobicContact CG2-CB 3.65Å; I181-V240 HydrophobicContact CD1-CG2 3.95Å; I181-V240 HydrophobicContact CG1-CG2 4.01Å
182	G	84.7	Confident	86.4	Confident	38 Å²	38	46.4 Å²	46.4	39%	0.392	25%	0.248	S	C	.	.	H	α-helix	trans	-57.5	-52	175	0	0	0	0	0	111.5	S178 E179 W184 K185 Y186	S178-G182 PolarHBondContact O-N 3.37Å; S178-G182 VanDerWaalsContact O-N 3.08Å; E179-G182 PolarHBondContact O-N 3.43Å; E179-G182 VanDerWaalsContact O-N 3.12Å; G182-W184 PolarHBondContact O-N 2.86Å; G182-K185 PolarHBondContact O-N 3.1Å; G182-Y186 PolarHBondContact O-N 3.13Å
183	I	88.6	Confident	86.3	Confident	17 Å²	17	40.5 Å²	40.5	9%	0.087	22%	0.217	C	C	.	.	H	α-helix	trans	-58.4	-47.2	176	-72.2	171.5	0	0	0	111.4	L164 L168 E179 L180 K185 Y186 Y187 F215	L164-I183 HydrophobicContact CD1-CD1 4.02Å; L164-I183 HydrophobicContact CD1-CG1 4.07Å; L164-I183 HydrophobicContact CD1-CG2 3.92Å; L164-I183 HydrophobicContact CD2-CG2 3.59Å; L164-I183 HydrophobicContact CG-CD1 4.23Å; L164-I183 HydrophobicContact CG-CG2 3.72Å; L168-I183 HydrophobicContact CD1-CD1 3.77Å; L168-I183 HydrophobicContact CD2-CD1 3.73Å; L168-I183 HydrophobicContact CG-CD1 3.82Å; E179-I183 PolarHBondContact O-N 3.01Å; L180-I183 PolarHBondContact O-N 3.11Å; I183-K185 PolarHBondContact O-N 2.84Å; I183-Y186 PolarHBondContact O-N 3.48Å; I183-Y187 VanDerWaalsContact O-CB 3.27Å; I183-Y187 WeakPolarHBondContact O-CB 3.49Å; I183-Y187 PolarHBondContact O-N 2.94Å; I183-F215 HydrophobicContact CG2-CE2 4.11Å; I183-F215 HydrophobicContact CG2-CZ 4.29Å
184	W	88.6	Confident	86.4	Confident	5 Å²	5	39.7 Å²	39.7	2%	0.019	21%	0.205	C	C	.	.	H	α-helix	trans	-60.3	-44.9	-180	170.4	-106.4	0	0	0	112.1	L180 I181 G182 Y186 Y187 I188 F215 H242 M243 T246 I247	L180-W184 VanDerWaalsContact O-CB 3.3Å; L180-W184 WeakPolarHBondContact O-CB 3.44Å; L180-W184 PolarHBondContact O-N 3.46Å; I181-W184 PolarHBondContact O-N 3.25Å; G182-W184 PolarHBondContact O-N 2.86Å; W184-Y186 PolarHBondContact O-N 3.05Å; W184-Y187 HydrophobicContact CE3-CD1 4.17Å; W184-Y187 AromaticContact CZ3-CD1 3.96Å; W184-Y187 HydrophobicContact CZ3-CD1 3.96Å; W184-Y187 HydrophobicContact CZ3-CE1 4.41Å; W184-Y187 PolarHBondContact O-N 3.18Å; W184-I188 HydrophobicContact CD2-CB 4.44Å; W184-I188 HydrophobicContact CD2-CG2 4.49Å; W184-I188 HydrophobicContact CH2-CB 4.11Å; W184-I188 HydrophobicContact CH2-CD1 3.94Å; W184-I188 HydrophobicContact CH2-CG1 4.06Å; W184-I188 HydrophobicContact CZ2-CB 3.79Å; W184-I188 HydrophobicContact CZ2-CD1 4.13Å; W184-I188 HydrophobicContact CZ2-CG1 3.75Å; W184-I188 HydrophobicContact CZ2-CG2 4.13Å; W184-I188 VanDerWaalsContact O-CG2 3.29Å; W184-I188 WeakPolarHBondContact O-CG2 3.25Å; W184-I188 PolarHBondContact O-N 3.43Å; W184-F215 HydrophobicContact CB-CZ 4.35Å; W184-F215 HydrophobicContact CE3-CD1 4.24Å; W184-F215 HydrophobicContact CE3-CD2 4.45Å; W184-F215 AromaticContact CE3-CE1 3.91Å; W184-F215 HydrophobicContact CE3-CE1 3.91Å; W184-F215 HydrophobicContact CE3-CE2 4.13Å; W184-F215 AromaticContact CE3-CZ 3.85Å; W184-F215 HydrophobicContact CE3-CZ 3.85Å; W184-F215 HydrophobicContact CZ3-CD1 4.36Å; W184-F215 HydrophobicContact CZ3-CE1 4.47Å; W184-F215 HydrophobicContact CZ3-CG 4.45Å; W184-H242 AromaticContact CE2-ND1 3.91Å; W184-H242 AromaticContact CZ2-ND1 3.84Å; W184-H242 AromaticContact NE1-ND1 3.35Å; W184-H242 PolarHBondContact NE1-ND1 3.07Å; W184-M243 HydrophobicContact CB-SD 3.99Å; W184-M243 HydrophobicContact CD2-CB 3.74Å; W184-M243 HydrophobicContact CD2-CG 3.51Å; W184-M243 HydrophobicContact CD2-SD 4Å; W184-M243 VanDerWaalsContact CE2-CA 3.5Å; W184-M243 HydrophobicContact CE3-CB 4.36Å; W184-M243 HydrophobicContact CE3-CG 3.66Å; W184-M243 HydrophobicContact CE3-SD 4.13Å; W184-M243 HydrophobicContact CG-CB 3.92Å; W184-M243 HydrophobicContact CG-CG 3.92Å; W184-M243 HydrophobicContact CG-SD 3.91Å; W184-M243 HydrophobicContact CH2-CG 4.36Å; W184-M243 HydrophobicContact CZ2-CB 4.15Å; W184-M243 HydrophobicContact CZ2-CG 4.28Å; W184-M243 HydrophobicContact CZ3-CG 4.08Å; W184-T246 HydrophobicContact CH2-CG2 3.84Å; W184-T246 HydrophobicContact CZ2-CG2 3.96Å; W184-I247 HydrophobicContact CH2-CG1 4.26Å; W184-I247 HydrophobicContact CZ3-CD1 4.32Å; W184-I247 HydrophobicContact CZ3-CG1 4.25Å
185	K	83.9	Confident	86.8	Confident	86 Å²	86	34.8 Å²	34.8	37%	0.374	18%	0.179	S	C	.	.	H	α-helix	trans	-58.5	-48.4	178.7	-80	177.9	173.8	-174.9	0	111.4	I181 G182 I183 N189 H239	I181-K185 HydrophobicContact CG2-CD 4.19Å; I181-K185 HydrophobicContact CG2-CG 4.39Å; I181-K185 WeakPolarHBondContact O-CB 3.48Å; I181-K185 WeakPolarHBondContact O-CG 3.3Å; I181-K185 PolarHBondContact O-N 3.41Å; G182-K185 PolarHBondContact O-N 3.1Å; I183-K185 PolarHBondContact O-N 2.84Å; K185-N189 VanDerWaalsContact O-CB 3.25Å; K185-N189 WeakPolarHBondContact O-CB 3.28Å; K185-N189 PolarHBondContact O-N 3.09Å; K185-N189 PolarHBondContact O-ND2 3.47Å; K185-H239 VanDerWaalsContact CE-CD2 3.48Å; K185-H239 WeakPolarHBondContact CE-CD2 3.39Å; K185-H239 WeakPolarHBondContact CE-CE1 3.29Å; K185-H239 WeakPolarHBondContact CE-NE2 3.35Å; K185-H239 PolarHBondContact NZ-NE2 3.04Å; K185-H239 VanDerWaalsContact NZ-NE2 3.11Å
186	Y	84	Confident	86.9	Confident	70 Å²	70	29.1 Å²	29.1	28%	0.275	15%	0.152	S	C	.	.	H	α-helix	trans	-62	-49.2	177.3	-172.8	-86.8	0	0	0	110.8	C122 G182 I183 W184 I188 N189 Y190 S191	C122-Y186 VanDerWaalsContact CA-OH 3.32Å; C122-Y186 WeakPolarHBondContact CA-OH 3.28Å; C122-Y186 HydrophobicContact CB-CE1 3.92Å; C122-Y186 HydrophobicContact CB-CE2 4.11Å; C122-Y186 WeakPolarHBondContact SG-CD1 3.43Å; C122-Y186 WeakPolarHBondContact SG-CE1 3.4Å; G182-Y186 PolarHBondContact O-N 3.13Å; I183-Y186 PolarHBondContact O-N 3.48Å; W184-Y186 PolarHBondContact O-N 3.05Å; Y186-I188 PolarHBondContact O-N 3.34Å; Y186-N189 PolarHBondContact O-N 3.4Å; Y186-Y190 AromaticContact CE1-CD1 3.59Å; Y186-Y190 HydrophobicContact CE1-CD1 3.59Å; Y186-Y190 HydrophobicContact CE1-CE1 4.39Å; Y186-Y190 HydrophobicContact CE1-CG 4.21Å; Y186-Y190 HydrophobicContact CE2-CD1 4.04Å; Y186-Y190 HydrophobicContact CE2-CG 4.07Å; Y186-Y190 AromaticContact CZ-CD1 3.29Å; Y186-Y190 AromaticContact CZ-CE1 3.86Å; Y186-Y190 AromaticContact CZ-CG 3.79Å; Y186-Y190 WeakPolarHBondContact O-CA 3.41Å; Y186-Y190 VanDerWaalsContact O-CB 3.26Å; Y186-Y190 WeakPolarHBondContact O-CB 3.27Å; Y186-Y190 PolarHBondContact O-N 3.05Å; Y186-Y190 WeakPolarHBondContact OH-CD1 3.31Å; Y186-Y190 WeakPolarHBondContact OH-CE1 3.42Å; Y186-S191 WeakPolarHBondContact CD1-OG 3.48Å; Y186-S191 VanDerWaalsContact CE1-OG 3.32Å; Y186-S191 WeakPolarHBondContact CE1-OG 3.48Å; Y186-S191 PolarHBondContact O-N 3.34Å
187	Y	87.4	Confident	86.7	Confident	6 Å²	6	29.2 Å²	29.2	2%	0.024	15%	0.153	C	C	.	.	I	π-helix	trans	-56.2	-48.3	-178.4	-177.5	-105.2	0	0	0	112.4	I120 M161 I183 W184 S191 Y192 L211 F215	I120-Y187 HydrophobicContact CG1-CE2 4.43Å; M161-Y187 HydrophobicContact CE-CD2 4.34Å; M161-Y187 HydrophobicContact CE-CE2 3.45Å; M161-Y187 VanDerWaalsContact CE-CE2 3.45Å; M161-Y187 WeakPolarHBondContact CE-OH 3.29Å; I183-Y187 VanDerWaalsContact O-CB 3.27Å; I183-Y187 WeakPolarHBondContact O-CB 3.49Å; I183-Y187 PolarHBondContact O-N 2.94Å; W184-Y187 HydrophobicContact CE3-CD1 4.17Å; W184-Y187 AromaticContact CZ3-CD1 3.96Å; W184-Y187 HydrophobicContact CZ3-CD1 3.96Å; W184-Y187 HydrophobicContact CZ3-CE1 4.41Å; W184-Y187 PolarHBondContact O-N 3.18Å; Y187-S191 PolarHBondContact O-N 3.1Å; Y187-Y192 VanDerWaalsContact O-CB 3.3Å; Y187-Y192 WeakPolarHBondContact O-CB 3.35Å; Y187-Y192 PolarHBondContact O-N 3.26Å; Y187-L211 WeakPolarHBondContact OH-CA 3.41Å; Y187-L211 VanDerWaalsContact OH-CB 3.27Å; Y187-L211 WeakPolarHBondContact OH-CB 3.42Å; Y187-L211 WeakPolarHBondContact OH-CD2 3.39Å; Y187-L211 PolarHBondContact OH-O 3.24Å; Y187-L211 VanDerWaalsContact OH-O 3.12Å; Y187-F215 AromaticContact CD1-CD2 3.6Å; Y187-F215 HydrophobicContact CD1-CD2 3.6Å; Y187-F215 AromaticContact CD1-CE2 3.97Å; Y187-F215 HydrophobicContact CD1-CE2 3.97Å; Y187-F215 HydrophobicContact CD1-CG 4.4Å; Y187-F215 HydrophobicContact CD2-CD2 4.34Å; Y187-F215 HydrophobicContact CE1-CB 4.2Å; Y187-F215 AromaticContact CE1-CD2 3.75Å; Y187-F215 HydrophobicContact CE1-CD2 3.75Å; Y187-F215 HydrophobicContact CE1-CG 4.27Å; Y187-F215 HydrophobicContact CE2-CD2 4.48Å; Y187-F215 AromaticContact CG-CD2 3.91Å; Y187-F215 HydrophobicContact CG-CD2 3.91Å; Y187-F215 HydrophobicContact CG-CE2 4Å
188	I	84.3	Confident	86.9	Confident	11 Å²	11	28.7 Å²	28.7	6%	0.056	15%	0.15	C	C	.	.	I	π-helix	trans	-80.3	-33.8	-174.9	-162.8	58.6	0	0	0	113.7	T16 W184 Y186 Y192 P193 T246 F250	T16-I188 HydrophobicContact CG2-CD1 4.5Å; W184-I188 HydrophobicContact CD2-CB 4.44Å; W184-I188 HydrophobicContact CD2-CG2 4.49Å; W184-I188 HydrophobicContact CH2-CB 4.11Å; W184-I188 HydrophobicContact CH2-CD1 3.94Å; W184-I188 HydrophobicContact CH2-CG1 4.06Å; W184-I188 HydrophobicContact CZ2-CB 3.79Å; W184-I188 HydrophobicContact CZ2-CD1 4.13Å; W184-I188 HydrophobicContact CZ2-CG1 3.75Å; W184-I188 HydrophobicContact CZ2-CG2 4.13Å; W184-I188 VanDerWaalsContact O-CG2 3.29Å; W184-I188 WeakPolarHBondContact O-CG2 3.25Å; W184-I188 PolarHBondContact O-N 3.43Å; Y186-I188 PolarHBondContact O-N 3.34Å; I188-Y192 HydrophobicContact CD1-CD1 3.98Å; I188-Y192 HydrophobicContact CD1-CD2 4.4Å; I188-Y192 HydrophobicContact CD1-CG 3.92Å; I188-P193 WeakPolarHBondContact O-CD 3.34Å; I188-T246 HydrophobicContact CD1-CG2 3.87Å; I188-T246 HydrophobicContact CG1-CG2 4.41Å; I188-F250 HydrophobicContact CD1-CE2 4.14Å; I188-F250 HydrophobicContact CD1-CZ 4.34Å
189	N	79.9	Confident	87.2	Confident	109 Å²	109	25.3 Å²	25.3	58%	0.583	13%	0.127	S	C	*	.	I	π-helix	trans	-88.7	-29.4	-177	-64.6	-32.4	0	0	0	112.7	K23 K185 Y186 P193	K23-N189 PolarHBondContact NZ-O 3.44Å; K185-N189 VanDerWaalsContact O-CB 3.25Å; K185-N189 WeakPolarHBondContact O-CB 3.28Å; K185-N189 PolarHBondContact O-N 3.09Å; K185-N189 PolarHBondContact O-ND2 3.47Å; Y186-N189 PolarHBondContact O-N 3.4Å; N189-P193 WeakPolarHBondContact O-CG 3.4Å
190	Y	82.3	Confident	87.1	Confident	82 Å²	82	24.9 Å²	24.9	32%	0.322	13%	0.128	S	C	.	.	I	π-helix	trans	-109.9	-65.6	-176.4	-170.2	-93.6	0	0	0	112.3	L126 Y186 P193 I194	L126-Y190 HydrophobicContact CD1-CE1 4.46Å; Y186-Y190 AromaticContact CE1-CD1 3.59Å; Y186-Y190 HydrophobicContact CE1-CD1 3.59Å; Y186-Y190 HydrophobicContact CE1-CE1 4.39Å; Y186-Y190 HydrophobicContact CE1-CG 4.21Å; Y186-Y190 HydrophobicContact CE2-CD1 4.04Å; Y186-Y190 HydrophobicContact CE2-CG 4.07Å; Y186-Y190 AromaticContact CZ-CD1 3.29Å; Y186-Y190 AromaticContact CZ-CE1 3.86Å; Y186-Y190 AromaticContact CZ-CG 3.79Å; Y186-Y190 WeakPolarHBondContact O-CA 3.41Å; Y186-Y190 VanDerWaalsContact O-CB 3.26Å; Y186-Y190 WeakPolarHBondContact O-CB 3.27Å; Y186-Y190 PolarHBondContact O-N 3.05Å; Y186-Y190 WeakPolarHBondContact OH-CD1 3.31Å; Y186-Y190 WeakPolarHBondContact OH-CE1 3.42Å; Y190-P193 VanDerWaalsContact O-CD 3.24Å; Y190-P193 WeakPolarHBondContact O-CD 3.32Å; Y190-P193 WeakPolarHBondContact O-CG 3.04Å; Y190-I194 HydrophobicContact CD1-CD1 3.8Å; Y190-I194 HydrophobicContact CD2-CD1 4Å; Y190-I194 HydrophobicContact CE1-CD1 3.45Å; Y190-I194 VanDerWaalsContact CE1-CD1 3.45Å; Y190-I194 HydrophobicContact CE2-CD1 3.65Å; Y190-I194 HydrophobicContact CG-CD1 4.08Å; Y190-I194 WeakPolarHBondContact O-CD1 3.24Å; Y190-I194 VanDerWaalsContact O-CG1 3.28Å; Y190-I194 WeakPolarHBondContact O-CG1 3.13Å; Y190-I194 PolarHBondContact O-N 3.45Å
191	S	87.1	Confident	86.9	Confident	0 Å²	0	27.5 Å²	27.5	0%	0	14%	0.144	C	C	.	.	I	π-helix	trans	-65.3	-50.4	-170.4	-49.8	0	0	0	0	112.8	I119 Y186 Y187 I194 I195	I119-S191 PolarHBondContact O-OG 3.47Å; Y186-S191 WeakPolarHBondContact CD1-OG 3.48Å; Y186-S191 VanDerWaalsContact CE1-OG 3.32Å; Y186-S191 WeakPolarHBondContact CE1-OG 3.48Å; Y186-S191 PolarHBondContact O-N 3.34Å; Y187-S191 PolarHBondContact O-N 3.1Å; S191-I194 PolarHBondContact O-N 2.95Å; S191-I195 VanDerWaalsContact O-CG1 3.31Å; S191-I195 WeakPolarHBondContact O-CG1 3.32Å; S191-I195 PolarHBondContact O-N 3.37Å
192	Y	87.9	Confident	87	Confident	2 Å²	2	27.2 Å²	27.2	1%	0.008	14%	0.143	C	C	.	.	H	α-helix	trans	-51.6	-58.3	-178	165.9	-99.1	0	0	0	113.4	T16 Y187 I188 I194 I195 L196 E208 L211 F250	T16-Y192 HydrophobicContact CG2-CE1 4.36Å; Y187-Y192 VanDerWaalsContact O-CB 3.3Å; Y187-Y192 WeakPolarHBondContact O-CB 3.35Å; Y187-Y192 PolarHBondContact O-N 3.26Å; I188-Y192 HydrophobicContact CD1-CD1 3.98Å; I188-Y192 HydrophobicContact CD1-CD2 4.4Å; I188-Y192 HydrophobicContact CD1-CG 3.92Å; Y192-I194 VanDerWaalsContact C-N 3.27Å; Y192-I194 PolarHBondContact O-N 3.34Å; Y192-I195 PolarHBondContact O-N 2.88Å; Y192-L196 HydrophobicContact CD1-CD1 4.33Å; Y192-L196 HydrophobicContact CE1-CD1 3.63Å; Y192-L196 HydrophobicContact CE1-CG 4.48Å; Y192-L196 HydrophobicContact CE2-CD1 3.99Å; Y192-L196 HydrophobicContact CE2-CD2 4.44Å; Y192-L196 HydrophobicContact CE2-CG 4.2Å; Y192-L196 VanDerWaalsContact CZ-CD1 3.44Å; Y192-L196 WeakPolarHBondContact O-CG 3.35Å; Y192-L196 PolarHBondContact O-N 3.15Å; Y192-E208 HydrophobicContact CE2-CG 3.95Å; Y192-E208 VanDerWaalsContact OH-CG 3.29Å; Y192-E208 WeakPolarHBondContact OH-CG 3.42Å; Y192-E208 PolarHBondContact OH-OE1 3.3Å; Y192-L211 HydrophobicContact CD2-CD1 3.72Å; Y192-L211 HydrophobicContact CE2-CD1 4.35Å; Y192-F250 HydrophobicContact CD2-CE2 4.07Å; Y192-F250 HydrophobicContact CD2-CZ 4.36Å; Y192-F250 HydrophobicContact CE1-CZ 4.24Å; Y192-F250 HydrophobicContact CE2-CE1 4.46Å; Y192-F250 AromaticContact CE2-CE2 3.56Å; Y192-F250 HydrophobicContact CE2-CE2 3.56Å; Y192-F250 AromaticContact CE2-CZ 3.54Å; Y192-F250 HydrophobicContact CE2-CZ 3.54Å; Y192-F250 AromaticContact CZ-CZ 3.47Å; Y192-F250 VanDerWaalsContact CZ-CZ 3.47Å; Y192-F250 WeakPolarHBondContact OH-CZ 3.46Å
193	P	84.7	Confident	87.2	Confident	2 Å²	2	29.5 Å²	29.5	1%	0.013	15%	0.151	C	C	.	.	H	α-helix	trans	-70.1	-24.3	-176.3	32.6	-40	0	0	0	112.7	K23 I188 N189 Y190 L197	K23-P193 HydrophobicContact CD-CB 3.95Å; K23-P193 HydrophobicContact CD-CG 3.84Å; I188-P193 WeakPolarHBondContact O-CD 3.34Å; N189-P193 WeakPolarHBondContact O-CG 3.4Å; Y190-P193 VanDerWaalsContact O-CD 3.24Å; Y190-P193 WeakPolarHBondContact O-CD 3.32Å; Y190-P193 WeakPolarHBondContact O-CG 3.04Å; P193-L197 WeakPolarHBondContact O-CG 3.09Å; P193-L197 PolarHBondContact O-N 3.31Å
194	I	86.2	Confident	87.1	Confident	15 Å²	15	31.8 Å²	31.8	8%	0.077	16%	0.161	C	C	.	.	H	α-helix	trans	-73.1	-42.3	174.7	-66.1	173.8	0	0	0	110.6	I119 I128 Y190 S191 Y192 L196 L197 I198	I119-I194 HydrophobicContact CD1-CG2 3.5Å; I119-I194 HydrophobicContact CG1-CG2 4.02Å; I119-I194 HydrophobicContact CG2-CB 4.26Å; I119-I194 HydrophobicContact CG2-CG2 4.24Å; I128-I194 HydrophobicContact CD1-CG2 3.9Å; I128-I194 HydrophobicContact CG2-CG2 3.74Å; Y190-I194 HydrophobicContact CD1-CD1 3.8Å; Y190-I194 HydrophobicContact CD2-CD1 4Å; Y190-I194 HydrophobicContact CE1-CD1 3.45Å; Y190-I194 VanDerWaalsContact CE1-CD1 3.45Å; Y190-I194 HydrophobicContact CE2-CD1 3.65Å; Y190-I194 HydrophobicContact CG-CD1 4.08Å; Y190-I194 WeakPolarHBondContact O-CD1 3.24Å; Y190-I194 VanDerWaalsContact O-CG1 3.28Å; Y190-I194 WeakPolarHBondContact O-CG1 3.13Å; Y190-I194 PolarHBondContact O-N 3.45Å; S191-I194 PolarHBondContact O-N 2.95Å; Y192-I194 VanDerWaalsContact C-N 3.27Å; Y192-I194 PolarHBondContact O-N 3.34Å; I194-L196 VanDerWaalsContact C-N 3.28Å; I194-L196 PolarHBondContact O-N 2.87Å; I194-L197 WeakPolarHBondContact O-CA 3.04Å; I194-L197 WeakPolarHBondContact O-CB 3.28Å; I194-L197 PolarHBondContact O-N 3.18Å; I194-I198 PolarHBondContact O-N 2.91Å; I194-I198 VanDerWaalsContact O-N 3.13Å
195	I	91.9	Very high	87	Confident	1 Å²	1	38.2 Å²	38.2	1%	0.005	19%	0.189	C	C	.	.	H	α-helix	trans	-63.4	-38.4	175.2	-65.1	166.1	0	0	0	110.1	I116 I119 I120 S191 Y192 L197 I198 F199 V207 L211	I116-I195 HydrophobicContact CG2-CD1 4.26Å; I119-I195 HydrophobicContact CG2-CD1 4.36Å; I119-I195 HydrophobicContact CG2-CG1 4.08Å; I120-I195 HydrophobicContact CD1-CD1 4.01Å; I120-I195 HydrophobicContact CG1-CD1 3.82Å; S191-I195 VanDerWaalsContact O-CG1 3.31Å; S191-I195 WeakPolarHBondContact O-CG1 3.32Å; S191-I195 PolarHBondContact O-N 3.37Å; Y192-I195 PolarHBondContact O-N 2.88Å; I195-L197 PolarHBondContact O-N 2.91Å; I195-I198 WeakPolarHBondContact O-CB 3.29Å; I195-I198 PolarHBondContact O-N 3.26Å; I195-I198 VanDerWaalsContact O-N 3.11Å; I195-F199 HydrophobicContact CG2-CD2 3.67Å; I195-F199 HydrophobicContact CG2-CE2 3.84Å; I195-F199 WeakPolarHBondContact O-CD2 3.5Å; I195-F199 PolarHBondContact O-N 3.45Å; I195-V207 HydrophobicContact CG2-CG1 4.4Å; I195-L211 HydrophobicContact CB-CD1 4.16Å; I195-L211 HydrophobicContact CD1-CD2 3.98Å; I195-L211 HydrophobicContact CG2-CD1 3.96Å; I195-L211 HydrophobicContact CG2-CD2 4.14Å
196	L	89	Confident	87.3	Confident	4 Å²	4	35.9 Å²	35.9	2%	0.021	18%	0.182	C	C	.	.	H	α-helix	trans	-58.4	-32.1	171.2	-71.9	-176.5	0	0	0	113.2	Y20 Y192 I194 F199 T200 Q204 V207 E208	Y20-L196 HydrophobicContact CD2-CB 3.53Å; Y20-L196 HydrophobicContact CD2-CD1 3.62Å; Y20-L196 HydrophobicContact CD2-CG 4.26Å; Y20-L196 HydrophobicContact CE2-CB 3.36Å; Y20-L196 HydrophobicContact CE2-CD1 4.15Å; Y20-L196 HydrophobicContact CE2-CG 4.41Å; Y20-L196 HydrophobicContact CG-CD1 3.98Å; Y192-L196 HydrophobicContact CD1-CD1 4.33Å; Y192-L196 HydrophobicContact CE1-CD1 3.63Å; Y192-L196 HydrophobicContact CE1-CG 4.48Å; Y192-L196 HydrophobicContact CE2-CD1 3.99Å; Y192-L196 HydrophobicContact CE2-CD2 4.44Å; Y192-L196 HydrophobicContact CE2-CG 4.2Å; Y192-L196 VanDerWaalsContact CZ-CD1 3.44Å; Y192-L196 WeakPolarHBondContact O-CG 3.35Å; Y192-L196 PolarHBondContact O-N 3.15Å; I194-L196 VanDerWaalsContact C-N 3.28Å; I194-L196 PolarHBondContact O-N 2.87Å; L196-F199 CarbonylContact O-C 3.52Å; L196-T200 PolarHBondContact O-N 2.94Å; L196-Q204 HydrophobicContact CD1-CG 4.42Å; L196-Q204 HydrophobicContact CD2-CG 4.16Å; L196-V207 HydrophobicContact CD2-CB 3.74Å; L196-V207 HydrophobicContact CD2-CG1 3.68Å; L196-E208 HydrophobicContact CD2-CG 4.47Å
197	L	87.9	Confident	87.7	Confident	6 Å²	6	32.6 Å²	32.6	3%	0.031	17%	0.169	C	C	.	.	H	α-helix	trans	-69.9	-39.3	174.9	-68.3	171.7	0	0	0	112	Y20 K23 L24 F27 I128 P193 I194 I195 F199 T200	Y20-L197 HydrophobicContact CE2-CD2 3.95Å; Y20-L197 HydrophobicContact CE2-CG 4.3Å; K23-L197 HydrophobicContact CB-CD1 4.19Å; L24-L197 HydrophobicContact CB-CD2 3.95Å; L24-L197 HydrophobicContact CD1-CD2 3.53Å; L24-L197 HydrophobicContact CG-CD2 4.36Å; F27-L197 HydrophobicContact CB-CD1 4.33Å; I128-L197 HydrophobicContact CD1-CB 4.32Å; I128-L197 HydrophobicContact CD1-CD1 4.17Å; P193-L197 WeakPolarHBondContact O-CG 3.09Å; P193-L197 PolarHBondContact O-N 3.31Å; I194-L197 WeakPolarHBondContact O-CA 3.04Å; I194-L197 WeakPolarHBondContact O-CB 3.28Å; I194-L197 PolarHBondContact O-N 3.18Å; I195-L197 PolarHBondContact O-N 2.91Å; L197-F199 VanDerWaalsContact C-N 3.34Å; L197-T200 WeakPolarHBondContact O-CB 3.35Å; L197-T200 WeakPolarHBondContact O-CG2 3.32Å; L197-T200 PolarHBondContact O-N 2.9Å; L197-T200 PolarHBondContact O-OG1 3.11Å
198	I	91.3	Very high	87.8	Confident	0 Å²	0	33.1 Å²	33.1	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-60.7	-46.2	174.9	-65.7	173.7	0	0	0	110	V112 A115 I116 I119 A131 V132 M135 I194 I195 T200	V112-I198 HydrophobicContact CG1-CG2 3.99Å; A115-I198 HydrophobicContact CB-CD1 4.22Å; I116-I198 HydrophobicContact CG1-CD1 4.3Å; I119-I198 HydrophobicContact CD1-CD1 3.47Å; I119-I198 VanDerWaalsContact CD1-CD1 3.47Å; A131-I198 HydrophobicContact CB-CD1 4.12Å; A131-I198 HydrophobicContact CB-CG1 4.25Å; V132-I198 HydrophobicContact CG2-CG1 4.23Å; M135-I198 HydrophobicContact CB-CG2 4.1Å; M135-I198 WeakPolarHBondContact CB-O 3.43Å; M135-I198 HydrophobicContact CG-CG2 4.29Å; M135-I198 WeakPolarHBondContact CG-O 3.38Å; I194-I198 PolarHBondContact O-N 2.91Å; I194-I198 VanDerWaalsContact O-N 3.13Å; I195-I198 WeakPolarHBondContact O-CB 3.29Å; I195-I198 PolarHBondContact O-N 3.26Å; I195-I198 VanDerWaalsContact O-N 3.11Å; I198-T200 VanDerWaalsContact C-N 3.27Å; I198-T200 PolarHBondContact O-N 3.37Å
199	F	93.2	Very high	88.1	Confident	2 Å²	2	34.4 Å²	34.4	1%	0.009	18%	0.177	C	C	.	.	T	Hydrogen-bonded Turn	trans	-88.4	32.3	-179.9	-72.5	-88.2	0	0	0	113.9	I116 M135 I149 I195 L196 L197 T201 V202 V207 M210	I116-F199 HydrophobicContact CD1-CE2 3.58Å; I116-F199 HydrophobicContact CD1-CZ 3.88Å; I116-F199 HydrophobicContact CG1-CE2 4.38Å; M135-F199 HydrophobicContact CE-CD1 3.49Å; M135-F199 VanDerWaalsContact CE-CD1 3.49Å; M135-F199 HydrophobicContact CE-CE1 3.39Å; M135-F199 HydrophobicContact CE-CZ 4.42Å; M135-F199 HydrophobicContact CG-CD1 4.42Å; M135-F199 HydrophobicContact SD-CD1 4.08Å; M135-F199 HydrophobicContact SD-CE1 3.83Å; M135-F199 HydrophobicContact SD-CZ 4.37Å; I149-F199 HydrophobicContact CD1-CD1 3.9Å; I149-F199 HydrophobicContact CD1-CE1 3.71Å; I195-F199 HydrophobicContact CG2-CD2 3.67Å; I195-F199 HydrophobicContact CG2-CE2 3.84Å; I195-F199 WeakPolarHBondContact O-CD2 3.5Å; I195-F199 PolarHBondContact O-N 3.45Å; L196-F199 CarbonylContact O-C 3.52Å; L197-F199 VanDerWaalsContact C-N 3.34Å; F199-T201 PolarHBondContact O-N 3.38Å; F199-T201 VanDerWaalsContact O-N 3.11Å; F199-V202 HydrophobicContact CB-CB 4.24Å; F199-V202 HydrophobicContact CB-CG2 4.36Å; F199-V202 HydrophobicContact CD1-CB 4.39Å; F199-V202 HydrophobicContact CD1-CG2 3.83Å; F199-V202 WeakPolarHBondContact O-CB 3.4Å; F199-V202 PolarHBondContact O-N 3.33Å; F199-V207 HydrophobicContact CB-CG1 4.12Å; F199-V207 HydrophobicContact CB-CG2 3.58Å; F199-V207 HydrophobicContact CD2-CG1 4.23Å; F199-V207 HydrophobicContact CG-CG1 4.28Å; F199-V207 HydrophobicContact CG-CG2 4.12Å; F199-M210 HydrophobicContact CE2-CE 4.25Å; F199-M210 HydrophobicContact CZ-CE 4.29Å
200	T	87.8	Confident	88.7	Confident	51 Å²	51	29.2 Å²	29.2	31%	0.313	15%	0.149	S	C	.	.	T	Hydrogen-bonded Turn	trans	-59.4	-23.8	-178.9	34.8	0	0	0	0	114.6	L24 L196 L197 I198 V202	L24-T200 HydrophobicContact CD1-CG2 4.35Å; L196-T200 PolarHBondContact O-N 2.94Å; L197-T200 WeakPolarHBondContact O-CB 3.35Å; L197-T200 WeakPolarHBondContact O-CG2 3.32Å; L197-T200 PolarHBondContact O-N 2.9Å; L197-T200 PolarHBondContact O-OG1 3.11Å; I198-T200 VanDerWaalsContact C-N 3.27Å; I198-T200 PolarHBondContact O-N 3.37Å; T200-V202 VanDerWaalsContact C-N 3.32Å
201	T	86.7	Confident	89.2	Confident	55 Å²	55	25.4 Å²	25.4	34%	0.337	13%	0.134	S	C	.	.	T	Hydrogen-bonded Turn	trans	-83.8	-5.5	175	45.4	0	0	0	0	113.9	R136 F199	R136-T201 HydrophobicContact CB-CG2 4.36Å; R136-T201 HydrophobicContact CG-CG2 3.7Å; F199-T201 PolarHBondContact O-N 3.38Å; F199-T201 VanDerWaalsContact O-N 3.11Å
202	V	88.9	Confident	89.4	Confident	9 Å²	9	25.5 Å²	25.5	6%	0.055	14%	0.135	C	C	.	.	S	Bend	trans	-105.1	142.2	-180	-178.4	0	0	0	0	109.3	M135 T145 I149 F199 T200 Q204 T206 V207	M135-V202 HydrophobicContact CE-CG2 4.26Å; T145-V202 HydrophobicContact CG2-CB 4.24Å; T145-V202 HydrophobicContact CG2-CG1 3.82Å; T145-V202 HydrophobicContact CG2-CG2 3.58Å; I149-V202 HydrophobicContact CD1-CG1 4.05Å; I149-V202 HydrophobicContact CG1-CG1 4.28Å; F199-V202 HydrophobicContact CB-CB 4.24Å; F199-V202 HydrophobicContact CB-CG2 4.36Å; F199-V202 HydrophobicContact CD1-CB 4.39Å; F199-V202 HydrophobicContact CD1-CG2 3.83Å; F199-V202 WeakPolarHBondContact O-CB 3.4Å; F199-V202 PolarHBondContact O-N 3.33Å; T200-V202 VanDerWaalsContact C-N 3.32Å; V202-Q204 PolarHBondContact O-N 3.36Å; V202-Q204 VanDerWaalsContact O-N 3.16Å; V202-T206 HydrophobicContact CG1-CG2 4.23Å; V202-V207 HydrophobicContact CB-CG2 3.94Å; V202-V207 HydrophobicContact CG1-CG2 3.76Å
203	P	89	Confident	89.5	Confident	87 Å²	87	26 Å²	26	57%	0.565	14%	0.139	S	C	*	.			trans	-52.6	124.4	174.2	-27.7	35.3	0	0	0	111.9	K205 T206 V207	P203-K205 VanDerWaalsContact C-N 3.27Å; P203-K205 PolarHBondContact O-N 3.25Å; P203-K205 VanDerWaalsContact O-N 3.15Å; P203-T206 VanDerWaalsContact O-CB 3.28Å; P203-T206 WeakPolarHBondContact O-CB 3.46Å; P203-T206 PolarHBondContact O-N 2.81Å; P203-V207 PolarHBondContact O-N 2.93Å
204	Q	87.3	Confident	89.9	Confident	64 Å²	64	26 Å²	26	30%	0.299	14%	0.138	S	C	.	.	H	α-helix	trans	-50.5	-45	-174.5	178	177.7	-19.5	0	0	112.7	L196 V202 T206 V207 E208	L196-Q204 HydrophobicContact CD1-CG 4.42Å; L196-Q204 HydrophobicContact CD2-CG 4.16Å; V202-Q204 PolarHBondContact O-N 3.36Å; V202-Q204 VanDerWaalsContact O-N 3.16Å; Q204-T206 PolarHBondContact O-N 3.32Å; Q204-V207 PolarHBondContact O-N 3.25Å; Q204-E208 HydrophobicContact CG-CG 4.06Å; Q204-E208 PolarHBondContact NE2-OE1 2.65Å; Q204-E208 WeakPolarHBondContact O-CG 3.47Å; Q204-E208 PolarHBondContact O-N 3.47Å
205	K	86.8	Confident	90.3	Very high	140 Å²	140	25.2 Å²	25.2	61%	0.609	13%	0.134	S	C	*	.	H	α-helix	trans	-57.7	-33.5	178.9	-70.1	-172.1	175.1	-171	0	113.5	P203 Y209	P203-K205 VanDerWaalsContact C-N 3.27Å; P203-K205 PolarHBondContact O-N 3.25Å; P203-K205 VanDerWaalsContact O-N 3.15Å; K205-Y209 WeakPolarHBondContact O-CB 3.34Å; K205-Y209 PolarHBondContact O-N 2.59Å
206	T	90.1	Very high	90.3	Very high	37 Å²	37	25.3 Å²	25.3	23%	0.227	14%	0.135	C	C	.	.	H	α-helix	trans	-67.4	-43.2	177.3	-60	0	0	0	0	110.6	I149 V202 P203 Q204 M210	I149-T206 HydrophobicContact CG1-CG2 4.18Å; I149-T206 HydrophobicContact CG2-CG2 4.03Å; V202-T206 HydrophobicContact CG1-CG2 4.23Å; P203-T206 VanDerWaalsContact O-CB 3.28Å; P203-T206 WeakPolarHBondContact O-CB 3.46Å; P203-T206 PolarHBondContact O-N 2.81Å; Q204-T206 PolarHBondContact O-N 3.32Å; T206-M210 WeakPolarHBondContact O-CB 3.28Å; T206-M210 PolarHBondContact O-N 3.41Å
207	V	91.4	Very high	90.4	Very high	1 Å²	1	29.2 Å²	29.2	1%	0.006	15%	0.152	C	C	.	.	H	α-helix	trans	-70.7	-41.6	178.7	-170.4	0	0	0	0	110.7	I195 L196 F199 V202 P203 Q204 Y209 M210 L211	I195-V207 HydrophobicContact CG2-CG1 4.4Å; L196-V207 HydrophobicContact CD2-CB 3.74Å; L196-V207 HydrophobicContact CD2-CG1 3.68Å; F199-V207 HydrophobicContact CB-CG1 4.12Å; F199-V207 HydrophobicContact CB-CG2 3.58Å; F199-V207 HydrophobicContact CD2-CG1 4.23Å; F199-V207 HydrophobicContact CG-CG1 4.28Å; F199-V207 HydrophobicContact CG-CG2 4.12Å; V202-V207 HydrophobicContact CB-CG2 3.94Å; V202-V207 HydrophobicContact CG1-CG2 3.76Å; P203-V207 PolarHBondContact O-N 2.93Å; Q204-V207 PolarHBondContact O-N 3.25Å; V207-Y209 VanDerWaalsContact C-N 3.34Å; V207-Y209 PolarHBondContact O-N 3.36Å; V207-M210 HydrophobicContact CG1-CE 4Å; V207-M210 PolarHBondContact O-N 2.83Å; V207-L211 HydrophobicContact CG1-CD1 3.99Å; V207-L211 HydrophobicContact CG1-CG 4.34Å; V207-L211 WeakPolarHBondContact O-CB 3.48Å; V207-L211 VanDerWaalsContact O-CG 3.32Å; V207-L211 WeakPolarHBondContact O-CG 3.33Å; V207-L211 PolarHBondContact O-N 2.94Å
208	E	89.2	Confident	90.6	Very high	17 Å²	17	29.9 Å²	29.9	8%	0.079	15%	0.154	C	C	.	.	H	α-helix	trans	-55.1	-49.2	173.2	-74.7	177.2	160.9	0	0	111.6	Y192 L196 Q204 L211 G212 F250	Y192-E208 HydrophobicContact CE2-CG 3.95Å; Y192-E208 VanDerWaalsContact OH-CG 3.29Å; Y192-E208 WeakPolarHBondContact OH-CG 3.42Å; Y192-E208 PolarHBondContact OH-OE1 3.3Å; L196-E208 HydrophobicContact CD2-CG 4.47Å; Q204-E208 HydrophobicContact CG-CG 4.06Å; Q204-E208 PolarHBondContact NE2-OE1 2.65Å; Q204-E208 WeakPolarHBondContact O-CG 3.47Å; Q204-E208 PolarHBondContact O-N 3.47Å; E208-L211 PolarHBondContact O-N 3.23Å; E208-G212 PolarHBondContact O-N 3.09Å; E208-F250 HydrophobicContact CB-CB 4.42Å; E208-F250 HydrophobicContact CB-CD1 3.98Å; E208-F250 HydrophobicContact CB-CE1 4.35Å; E208-F250 HydrophobicContact CB-CG 4.08Å; E208-F250 HydrophobicContact CG-CD1 4.26Å; E208-F250 HydrophobicContact CG-CE1 4.15Å
209	Y	90.6	Very high	90.7	Very high	39 Å²	39	29.9 Å²	29.9	15%	0.153	15%	0.154	C	C	.	.	H	α-helix	trans	-59.5	-51.1	176.4	172.7	-100.8	0	0	0	111.7	K205 V207 L211 G212 V213 C251 R254	K205-Y209 WeakPolarHBondContact O-CB 3.34Å; K205-Y209 PolarHBondContact O-N 2.59Å; V207-Y209 VanDerWaalsContact C-N 3.34Å; V207-Y209 PolarHBondContact O-N 3.36Å; Y209-L211 VanDerWaalsContact C-N 3.31Å; Y209-L211 PolarHBondContact O-N 3.03Å; Y209-G212 PolarHBondContact O-N 2.9Å; Y209-V213 HydrophobicContact CD1-CG1 4.48Å; Y209-V213 HydrophobicContact CE1-CB 4.46Å; Y209-V213 HydrophobicContact CE1-CG1 4.06Å; Y209-V213 HydrophobicContact CE2-CB 4.13Å; Y209-V213 HydrophobicContact CE2-CG2 4.38Å; Y209-V213 WeakPolarHBondContact O-CB 3.07Å; Y209-V213 WeakPolarHBondContact O-CG1 3.07Å; Y209-V213 PolarHBondContact O-N 3.41Å; Y209-C251 HydrophobicContact CD2-CB 4.43Å; Y209-C251 HydrophobicContact CE2-CB 4.43Å; Y209-R254 HydrophobicContact CD2-CB 4.03Å; Y209-R254 HydrophobicContact CD2-CG 4.17Å; Y209-R254 HydrophobicContact CE2-CB 3.42Å; Y209-R254 VanDerWaalsContact CE2-CB 3.42Å; Y209-R254 HydrophobicContact CE2-CG 3.97Å; Y209-R254 VanDerWaalsContact CZ-CD 3.47Å
210	M	92.9	Very high	90.7	Very high	0 Å²	0	29.9 Å²	29.9	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-56.3	-44.9	-179.1	177.9	-171.1	63.4	0	0	111.9	I149 C152 E153 L157 F199 T206 V207 V213 S214	I149-M210 HydrophobicContact CD1-CE 4.21Å; I149-M210 HydrophobicContact CD1-SD 3.95Å; I149-M210 HydrophobicContact CG2-CB 4.38Å; I149-M210 HydrophobicContact CG2-CG 4.37Å; I149-M210 HydrophobicContact CG2-SD 3.91Å; C152-M210 HydrophobicContact CB-SD 3.81Å; E153-M210 HydrophobicContact CB-CG 4.07Å; E153-M210 HydrophobicContact CG-CG 4.44Å; L157-M210 HydrophobicContact CD1-CE 4.07Å; L157-M210 HydrophobicContact CD1-CG 3.56Å; L157-M210 HydrophobicContact CD1-SD 3.9Å; F199-M210 HydrophobicContact CE2-CE 4.25Å; F199-M210 HydrophobicContact CZ-CE 4.29Å; T206-M210 WeakPolarHBondContact O-CB 3.28Å; T206-M210 PolarHBondContact O-N 3.41Å; V207-M210 HydrophobicContact CG1-CE 4Å; V207-M210 PolarHBondContact O-N 2.83Å; M210-V213 WeakPolarHBondContact O-CG1 3.47Å; M210-S214 VanDerWaalsContact O-CB 3.28Å; M210-S214 WeakPolarHBondContact O-CB 3.48Å; M210-S214 PolarHBondContact O-N 2.84Å; M210-S214 VanDerWaalsContact O-N 3.16Å; M210-S214 PolarHBondContact O-OG 2.86Å
211	L	93.6	Very high	90.8	Very high	1 Å²	1	30.3 Å²	30.3	1%	0.005	15%	0.153	C	C	.	.	H	α-helix	trans	-69.4	-47.4	179	-71.1	178.5	0	0	0	111.6	L157 Y187 Y192 I195 V207 E208 Y209 S214 F215	L157-L211 HydrophobicContact CD1-CD2 4.06Å; L157-L211 HydrophobicContact CD2-CD2 4.11Å; Y187-L211 WeakPolarHBondContact OH-CA 3.41Å; Y187-L211 VanDerWaalsContact OH-CB 3.27Å; Y187-L211 WeakPolarHBondContact OH-CB 3.42Å; Y187-L211 WeakPolarHBondContact OH-CD2 3.39Å; Y187-L211 PolarHBondContact OH-O 3.24Å; Y187-L211 VanDerWaalsContact OH-O 3.12Å; Y192-L211 HydrophobicContact CD2-CD1 3.72Å; Y192-L211 HydrophobicContact CE2-CD1 4.35Å; I195-L211 HydrophobicContact CB-CD1 4.16Å; I195-L211 HydrophobicContact CD1-CD2 3.98Å; I195-L211 HydrophobicContact CG2-CD1 3.96Å; I195-L211 HydrophobicContact CG2-CD2 4.14Å; V207-L211 HydrophobicContact CG1-CD1 3.99Å; V207-L211 HydrophobicContact CG1-CG 4.34Å; V207-L211 WeakPolarHBondContact O-CB 3.48Å; V207-L211 VanDerWaalsContact O-CG 3.32Å; V207-L211 WeakPolarHBondContact O-CG 3.33Å; V207-L211 PolarHBondContact O-N 2.94Å; E208-L211 PolarHBondContact O-N 3.23Å; Y209-L211 VanDerWaalsContact C-N 3.31Å; Y209-L211 PolarHBondContact O-N 3.03Å; L211-S214 PolarHBondContact O-N 3.3Å; L211-F215 PolarHBondContact O-N 3.43Å; L211-F215 VanDerWaalsContact O-N 3.11Å
212	G	91.2	Very high	91.1	Very high	3 Å²	3	34.8 Å²	34.8	3%	0.031	16%	0.163	C	C	.	.	H	α-helix	trans	-60.8	-46.5	178.4	0	0	0	0	0	113	E208 Y209 S214 F215 L216	E208-G212 PolarHBondContact O-N 3.09Å; Y209-G212 PolarHBondContact O-N 2.9Å; G212-S214 VanDerWaalsContact C-N 3.34Å; G212-S214 PolarHBondContact O-N 3.49Å; G212-F215 PolarHBondContact O-N 2.67Å; G212-L216 WeakPolarHBondContact O-CB 3.49Å; G212-L216 PolarHBondContact O-N 3.29Å
213	V	90.7	Very high	91.1	Very high	13 Å²	13	35.5 Å²	35.5	8%	0.079	17%	0.166	C	C	.	.	H	α-helix	trans	-68.8	-35.4	-178.7	78.4	0	0	0	0	111.4	E153 Y209 M210 L216 K217 C251	E153-V213 HydrophobicContact CG-CG1 4.44Å; Y209-V213 HydrophobicContact CD1-CG1 4.48Å; Y209-V213 HydrophobicContact CE1-CB 4.46Å; Y209-V213 HydrophobicContact CE1-CG1 4.06Å; Y209-V213 HydrophobicContact CE2-CB 4.13Å; Y209-V213 HydrophobicContact CE2-CG2 4.38Å; Y209-V213 WeakPolarHBondContact O-CB 3.07Å; Y209-V213 WeakPolarHBondContact O-CG1 3.07Å; Y209-V213 PolarHBondContact O-N 3.41Å; M210-V213 WeakPolarHBondContact O-CG1 3.47Å; V213-L216 PolarHBondContact O-N 3.28Å; V213-K217 WeakPolarHBondContact O-CB 3.18Å; V213-K217 PolarHBondContact O-N 3.45Å; V213-C251 PolarHBondContact N-SG 2.81Å
214	S	92.2	Very high	91.2	Very high	0 Å²	0	38 Å²	38	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-64.8	-46.1	176.9	-66.5	0	0	0	0	111.5	L157 M210 L211 G212 Y218	L157-S214 WeakPolarHBondContact CB-OG 3.33Å; L157-S214 WeakPolarHBondContact CD1-OG 3.47Å; M210-S214 VanDerWaalsContact O-CB 3.28Å; M210-S214 WeakPolarHBondContact O-CB 3.48Å; M210-S214 PolarHBondContact O-N 2.84Å; M210-S214 VanDerWaalsContact O-N 3.16Å; M210-S214 PolarHBondContact O-OG 2.86Å; L211-S214 PolarHBondContact O-N 3.3Å; G212-S214 VanDerWaalsContact C-N 3.34Å; G212-S214 PolarHBondContact O-N 3.49Å; S214-Y218 VanDerWaalsContact O-CB 3.3Å; S214-Y218 WeakPolarHBondContact O-CB 3.46Å; S214-Y218 WeakPolarHBondContact O-CD2 3.38Å; S214-Y218 PolarHBondContact O-N 3.25Å
215	F	94.3	Very high	91.4	Very high	0 Å²	0	35 Å²	35	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-63.9	-43.5	176.3	-162.4	-78.6	0	0	0	111.2	M161 L180 I183 W184 Y187 L211 G212 I219 L220 M243 I247	M161-F215 HydrophobicContact CE-CB 4.35Å; M161-F215 HydrophobicContact CE-CD2 4.3Å; M161-F215 HydrophobicContact SD-CD2 4.17Å; L180-F215 HydrophobicContact CD1-CE1 4.33Å; L180-F215 HydrophobicContact CD1-CZ 4.18Å; I183-F215 HydrophobicContact CG2-CE2 4.11Å; I183-F215 HydrophobicContact CG2-CZ 4.29Å; W184-F215 HydrophobicContact CB-CZ 4.35Å; W184-F215 HydrophobicContact CE3-CD1 4.24Å; W184-F215 HydrophobicContact CE3-CD2 4.45Å; W184-F215 AromaticContact CE3-CE1 3.91Å; W184-F215 HydrophobicContact CE3-CE1 3.91Å; W184-F215 HydrophobicContact CE3-CE2 4.13Å; W184-F215 AromaticContact CE3-CZ 3.85Å; W184-F215 HydrophobicContact CE3-CZ 3.85Å; W184-F215 HydrophobicContact CZ3-CD1 4.36Å; W184-F215 HydrophobicContact CZ3-CE1 4.47Å; W184-F215 HydrophobicContact CZ3-CG 4.45Å; Y187-F215 AromaticContact CD1-CD2 3.6Å; Y187-F215 HydrophobicContact CD1-CD2 3.6Å; Y187-F215 AromaticContact CD1-CE2 3.97Å; Y187-F215 HydrophobicContact CD1-CE2 3.97Å; Y187-F215 HydrophobicContact CD1-CG 4.4Å; Y187-F215 HydrophobicContact CD2-CD2 4.34Å; Y187-F215 HydrophobicContact CE1-CB 4.2Å; Y187-F215 AromaticContact CE1-CD2 3.75Å; Y187-F215 HydrophobicContact CE1-CD2 3.75Å; Y187-F215 HydrophobicContact CE1-CG 4.27Å; Y187-F215 HydrophobicContact CE2-CD2 4.48Å; Y187-F215 AromaticContact CG-CD2 3.91Å; Y187-F215 HydrophobicContact CG-CD2 3.91Å; Y187-F215 HydrophobicContact CG-CE2 4Å; L211-F215 PolarHBondContact O-N 3.43Å; L211-F215 VanDerWaalsContact O-N 3.11Å; G212-F215 PolarHBondContact O-N 2.67Å; F215-I219 HydrophobicContact CD1-CB 4.47Å; F215-I219 HydrophobicContact CD2-CD1 3.83Å; F215-I219 HydrophobicContact CE1-CB 4.44Å; F215-I219 HydrophobicContact CE1-CD1 4.48Å; F215-I219 HydrophobicContact CE1-CG2 4.43Å; F215-I219 HydrophobicContact CE2-CD1 3.69Å; F215-I219 HydrophobicContact CG-CD1 4.3Å; F215-I219 HydrophobicContact CZ-CD1 4.03Å; F215-I219 WeakPolarHBondContact O-CA 3.39Å; F215-I219 VanDerWaalsContact O-CB 3.28Å; F215-I219 WeakPolarHBondContact O-CB 3.47Å; F215-I219 PolarHBondContact O-N 2.87Å; F215-I219 VanDerWaalsContact O-N 3.09Å; F215-L220 HydrophobicContact CD1-CD1 4.37Å; F215-L220 HydrophobicContact CD1-CD2 4.45Å; F215-L220 HydrophobicContact CD1-CG 4.07Å; F215-L220 HydrophobicContact CE1-CD2 3.98Å; F215-L220 HydrophobicContact CE1-CG 4.1Å; F215-L220 PolarHBondContact O-N 3.13Å; F215-M243 HydrophobicContact CE1-SD 3.84Å; F215-M243 HydrophobicContact CZ-SD 4.45Å; F215-I247 HydrophobicContact CD1-CD1 3.94Å
216	L	92.4	Very high	91.4	Very high	2 Å²	2	29.1 Å²	29.1	1%	0.01	13%	0.129	C	C	.	.	I	π-helix	trans	-59	-57.3	176.9	180	59.1	0	0	0	111.8	G212 V213 L220 E221 I247 L255 Y263	G212-L216 WeakPolarHBondContact O-CB 3.49Å; G212-L216 PolarHBondContact O-N 3.29Å; V213-L216 PolarHBondContact O-N 3.28Å; L216-L220 HydrophobicContact CD1-CB 4.17Å; L216-L220 HydrophobicContact CD1-CD1 4.07Å; L216-L220 WeakPolarHBondContact O-CB 3.13Å; L216-L220 PolarHBondContact O-N 3.27Å; L216-L220 VanDerWaalsContact O-N 3.14Å; L216-E221 HydrophobicContact CD1-CG 4.27Å; L216-E221 HydrophobicContact CG-CG 4.3Å; L216-E221 PolarHBondContact O-N 3.48Å; L216-I247 HydrophobicContact CB-CG2 3.88Å; L216-I247 HydrophobicContact CD1-CG2 4.15Å; L216-I247 HydrophobicContact CD2-CG2 3.95Å; L216-I247 HydrophobicContact CG-CG2 4.22Å; L216-L255 HydrophobicContact CD2-CD1 4.38Å; L216-L255 HydrophobicContact CD2-CD2 4.25Å; L216-Y263 HydrophobicContact CD1-CE1 4.36Å; L216-Y263 HydrophobicContact CD1-CE2 4.42Å; L216-Y263 WeakPolarHBondContact CD1-OH 3.35Å; L216-Y263 HydrophobicContact CD2-CE2 4.37Å
217	K	91.3	Very high	91.2	Very high	86 Å²	86	30.6 Å²	30.6	37%	0.374	14%	0.135	S	C	.	.	I	π-helix	trans	-69.8	-46.6	-172.5	-176.9	179.7	179.4	-177.4	0	112.2	V213 R222	V213-K217 WeakPolarHBondContact O-CB 3.18Å; V213-K217 PolarHBondContact O-N 3.45Å; K217-R222 VanDerWaalsContact O-CG 3.32Å; K217-R222 WeakPolarHBondContact O-CG 3.11Å
218	Y	91.6	Very high	91	Very high	20 Å²	20	31.9 Å²	31.9	8%	0.078	14%	0.142	C	C	.	.	I	π-helix	trans	-90.2	-19.4	-170.4	-61.1	-60.1	0	0	0	113.6	R158 M161 R165 S214	R158-Y218 HydrophobicContact CB-CD2 4.39Å; R158-Y218 HydrophobicContact CB-CE1 4.06Å; R158-Y218 HydrophobicContact CB-CE2 3.87Å; R158-Y218 HydrophobicContact CG-CD1 4.11Å; R158-Y218 HydrophobicContact CG-CE1 3.62Å; R158-Y218 HydrophobicContact CG-CE2 4.37Å; M161-Y218 HydrophobicContact CB-CG 4.43Å; R165-Y218 VanDerWaalsContact CD-O 3.29Å; R165-Y218 WeakPolarHBondContact CD-O 3.25Å; R165-Y218 PolarHBondContact NH1-O 3.03Å; S214-Y218 VanDerWaalsContact O-CB 3.3Å; S214-Y218 WeakPolarHBondContact O-CB 3.46Å; S214-Y218 WeakPolarHBondContact O-CD2 3.38Å; S214-Y218 PolarHBondContact O-N 3.25Å
219	I	93.1	Very high	90.7	Very high	0 Å²	0	31.1 Å²	31.1	0%	0	14%	0.138	C	C	.	.	I	π-helix	trans	-110.7	-69.5	175.3	-53.2	-175.5	0	0	0	110.4	M161 L164 L168 L180 F215 E221 R222 M223	M161-I219 HydrophobicContact CB-CD1 4.45Å; M161-I219 HydrophobicContact CB-CG1 4.2Å; M161-I219 HydrophobicContact SD-CD1 3.69Å; M161-I219 HydrophobicContact SD-CG1 4.27Å; L164-I219 HydrophobicContact CD2-CD1 3.96Å; L164-I219 HydrophobicContact CG-CD1 4.31Å; L168-I219 HydrophobicContact CD1-CG2 4.24Å; L180-I219 HydrophobicContact CD1-CG2 3.86Å; F215-I219 HydrophobicContact CD1-CB 4.47Å; F215-I219 HydrophobicContact CD2-CD1 3.83Å; F215-I219 HydrophobicContact CE1-CB 4.44Å; F215-I219 HydrophobicContact CE1-CD1 4.48Å; F215-I219 HydrophobicContact CE1-CG2 4.43Å; F215-I219 HydrophobicContact CE2-CD1 3.69Å; F215-I219 HydrophobicContact CG-CD1 4.3Å; F215-I219 HydrophobicContact CZ-CD1 4.03Å; F215-I219 WeakPolarHBondContact O-CA 3.39Å; F215-I219 VanDerWaalsContact O-CB 3.28Å; F215-I219 WeakPolarHBondContact O-CB 3.47Å; F215-I219 PolarHBondContact O-N 2.87Å; F215-I219 VanDerWaalsContact O-N 3.09Å; I219-E221 PolarHBondContact O-N 3.28Å; I219-R222 PolarHBondContact O-N 3.07Å; I219-M223 HydrophobicContact CG2-SD 4.32Å; I219-M223 VanDerWaalsContact O-CB 3.24Å; I219-M223 WeakPolarHBondContact O-CB 3.37Å; I219-M223 WeakPolarHBondContact O-CG 3.32Å; I219-M223 PolarHBondContact O-N 3Å
220	L	93.1	Very high	90.3	Very high	2 Å²	2	33.1 Å²	33.1	1%	0.01	15%	0.148	C	C	.	.	I	π-helix	trans	-64.4	-48.1	-167.3	-59.5	-174.9	0	0	0	114	L180 F215 L216 K224 I225 M243 Y244 I247	L180-L220 HydrophobicContact CD1-CD2 4.17Å; L180-L220 HydrophobicContact CD2-CD2 3.87Å; F215-L220 HydrophobicContact CD1-CD1 4.37Å; F215-L220 HydrophobicContact CD1-CD2 4.45Å; F215-L220 HydrophobicContact CD1-CG 4.07Å; F215-L220 HydrophobicContact CE1-CD2 3.98Å; F215-L220 HydrophobicContact CE1-CG 4.1Å; F215-L220 PolarHBondContact O-N 3.13Å; L216-L220 HydrophobicContact CD1-CB 4.17Å; L216-L220 HydrophobicContact CD1-CD1 4.07Å; L216-L220 WeakPolarHBondContact O-CB 3.13Å; L216-L220 PolarHBondContact O-N 3.27Å; L216-L220 VanDerWaalsContact O-N 3.14Å; L220-K224 PolarHBondContact O-N 3.31Å; L220-K224 VanDerWaalsContact O-N 3.13Å; L220-I225 HydrophobicContact CD2-CB 4.27Å; L220-I225 HydrophobicContact CD2-CG1 3.88Å; L220-I225 HydrophobicContact CD2-CG2 4.41Å; L220-I225 PolarHBondContact O-N 3.24Å; L220-I225 VanDerWaalsContact O-N 3.1Å; L220-M243 HydrophobicContact CD1-CE 4.25Å; L220-M243 HydrophobicContact CD1-CG 4.47Å; L220-M243 HydrophobicContact CD1-SD 4.35Å; L220-M243 HydrophobicContact CD2-CE 3.73Å; L220-M243 HydrophobicContact CD2-SD 3.93Å; L220-Y244 HydrophobicContact CD1-CE1 3.96Å; L220-I247 HydrophobicContact CD1-CD1 3.38Å; L220-I247 HydrophobicContact CG-CD1 4.45Å
221	E	91.5	Very high	89.7	Confident	61 Å²	61	43 Å²	43	29%	0.285	19%	0.185	S	C	.	.	I	π-helix	trans	-67.3	-46.5	-180	-71.1	-175.7	161.2	0	0	110.7	L216 I219 M223 K224 K259	L216-E221 HydrophobicContact CD1-CG 4.27Å; L216-E221 HydrophobicContact CG-CG 4.3Å; L216-E221 PolarHBondContact O-N 3.48Å; I219-E221 PolarHBondContact O-N 3.28Å; E221-M223 VanDerWaalsContact C-N 3.31Å; E221-M223 PolarHBondContact O-N 3.27Å; E221-K224 PolarHBondContact O-N 3.5Å; E221-K259 IonicContact OE1-NZ 2.7Å; E221-K259 PolarHBondContact OE1-NZ 2.97Å; E221-K259 IonicContact OE2-NZ 3.9Å
222	R	90.9	Very high	88.8	Confident	149 Å²	149	44.9 Å²	44.9	56%	0.562	19%	0.194	S	C	*	.	T	Hydrogen-bonded Turn	trans	-64.1	-35	-179.8	-75.4	-72.7	-176.7	175.1	2.1	113	D71 K217 I219 K224	D71-R222 IonicContact OD1-NH1 3.56Å; K217-R222 VanDerWaalsContact O-CG 3.32Å; K217-R222 WeakPolarHBondContact O-CG 3.11Å; I219-R222 PolarHBondContact O-N 3.07Å; R222-K224 VanDerWaalsContact C-N 3.3Å
223	M	90.8	Very high	87.5	Confident	24 Å²	24	54.6 Å²	54.6	12%	0.118	24%	0.235	C	C	.	.	T	Hydrogen-bonded Turn	trans	-82.7	-5.3	174.9	-67.3	-155.6	73.8	0	0	113.9	R165 L168 L176 I219 E221 I225	R165-M223 HydrophobicContact CG-CG 3.64Å; R165-M223 HydrophobicContact CG-SD 3.74Å; L168-M223 HydrophobicContact CB-CE 3.48Å; L168-M223 VanDerWaalsContact CB-CE 3.48Å; L168-M223 HydrophobicContact CB-SD 3.46Å; L168-M223 WeakPolarHBondContact CB-SD 3.42Å; L168-M223 HydrophobicContact CD1-SD 3.58Å; L168-M223 VanDerWaalsContact CD1-SD 3.58Å; L168-M223 HydrophobicContact CG-SD 4.2Å; L168-M223 WeakPolarHBondContact O-CE 2.99Å; L176-M223 HydrophobicContact CD1-CE 3.3Å; L176-M223 HydrophobicContact CD1-SD 4.11Å; L176-M223 HydrophobicContact CD2-CE 3.89Å; L176-M223 HydrophobicContact CG-CE 4.23Å; I219-M223 HydrophobicContact CG2-SD 4.32Å; I219-M223 VanDerWaalsContact O-CB 3.24Å; I219-M223 WeakPolarHBondContact O-CB 3.37Å; I219-M223 WeakPolarHBondContact O-CG 3.32Å; I219-M223 PolarHBondContact O-N 3Å; E221-M223 VanDerWaalsContact C-N 3.31Å; E221-M223 PolarHBondContact O-N 3.27Å; M223-I225 HydrophobicContact CB-CD1 3.56Å; M223-I225 HydrophobicContact CB-CG1 3.77Å; M223-I225 HydrophobicContact CG-CD1 4.5Å; M223-I225 PolarHBondContact O-N 3.28Å; M223-I225 HydrophobicContact SD-CD1 4.23Å
224	K	90.9	Very high	85.9	Confident	138 Å²	138	59.4 Å²	59.4	60%	0.6	26%	0.26	S	S	*	.	T	Hydrogen-bonded Turn	trans	51.5	42.3	-175.5	-56.4	180	-179.9	178	0	112.2	L220 E221 R222 E226 D227 I228	L220-K224 PolarHBondContact O-N 3.31Å; L220-K224 VanDerWaalsContact O-N 3.13Å; E221-K224 PolarHBondContact O-N 3.5Å; R222-K224 VanDerWaalsContact C-N 3.3Å; K224-E226 PolarHBondContact O-N 3.45Å; K224-E226 VanDerWaalsContact O-N 3.11Å; K224-D227 HydrophobicContact CB-CB 4.41Å; K224-D227 WeakPolarHBondContact O-CB 3.37Å; K224-D227 PolarHBondContact O-N 3.17Å; K224-I228 PolarHBondContact O-N 3.07Å
225	I	89.9	Confident	84.4	Confident	1 Å²	1	67 Å²	67	1%	0.005	29%	0.294	C	S	.	.	H	α-helix	trans	-56.3	-33	-176.1	-62.8	-56.6	0	0	0	111.8	L176 I177 L180 L220 M223 D227 I228 I229	L176-I225 HydrophobicContact CD2-CD1 4.14Å; L176-I225 HydrophobicContact CG-CD1 4.38Å; I177-I225 HydrophobicContact CD1-CG2 4.11Å; L180-I225 HydrophobicContact CD2-CB 4.49Å; L180-I225 HydrophobicContact CD2-CD1 3.76Å; L180-I225 HydrophobicContact CD2-CG1 3.8Å; L180-I225 HydrophobicContact CD2-CG2 3.87Å; L220-I225 HydrophobicContact CD2-CB 4.27Å; L220-I225 HydrophobicContact CD2-CG1 3.88Å; L220-I225 HydrophobicContact CD2-CG2 4.41Å; L220-I225 PolarHBondContact O-N 3.24Å; L220-I225 VanDerWaalsContact O-N 3.1Å; M223-I225 HydrophobicContact CB-CD1 3.56Å; M223-I225 HydrophobicContact CB-CG1 3.77Å; M223-I225 HydrophobicContact CG-CD1 4.5Å; M223-I225 PolarHBondContact O-N 3.28Å; M223-I225 HydrophobicContact SD-CD1 4.23Å; I225-D227 VanDerWaalsContact C-N 3.32Å; I225-D227 PolarHBondContact O-N 2.6Å; I225-I228 HydrophobicContact CD1-CD1 4Å; I225-I228 PolarHBondContact O-N 3.36Å; I225-I229 HydrophobicContact CG2-CD1 3.73Å; I225-I229 HydrophobicContact CG2-CG1 4.2Å; I225-I229 WeakPolarHBondContact O-CB 3.5Å; I225-I229 VanDerWaalsContact O-CG1 3.31Å; I225-I229 WeakPolarHBondContact O-CG1 3.29Å; I225-I229 PolarHBondContact O-N 2.93Å
226	E	86.7	Confident	82.9	Confident	18 Å²	18	68.2 Å²	68.2	8%	0.084	30%	0.3	C	S	.	.	H	α-helix	trans	-58.9	-41.1	175.3	-60.6	-178.2	-148.6	0	0	113.1	K224 I228 I229 K230 Q262 Y263 L266	K224-E226 PolarHBondContact O-N 3.45Å; K224-E226 VanDerWaalsContact O-N 3.11Å; E226-I228 VanDerWaalsContact C-N 3.33Å; E226-I229 PolarHBondContact O-N 3Å; E226-K230 WeakPolarHBondContact O-CB 3.3Å; E226-K230 WeakPolarHBondContact O-CG 3.28Å; E226-K230 PolarHBondContact O-N 2.9Å; E226-K230 IonicContact OE2-NZ 4Å; E226-Q262 PolarHBondContact OE2-NE2 2.87Å; E226-Y263 HydrophobicContact CG-CE1 4.29Å; E226-Y263 WeakPolarHBondContact OE1-CE1 3.46Å; E226-Y263 PolarHBondContact OE1-OH 3.32Å; E226-L266 HydrophobicContact CB-CD1 4.36Å; E226-L266 HydrophobicContact CB-CD2 4.46Å; E226-L266 HydrophobicContact CG-CD2 3.92Å
227	D	87.6	Confident	81.8	Confident	67 Å²	67	71.7 Å²	71.7	36%	0.358	32%	0.318	S	S	.	.	H	α-helix	trans	-69.9	-35.9	-179.2	-67.7	-20.7	0	0	0	110.9	K224 I225 K230 R231	K224-D227 HydrophobicContact CB-CB 4.41Å; K224-D227 WeakPolarHBondContact O-CB 3.37Å; K224-D227 PolarHBondContact O-N 3.17Å; I225-D227 VanDerWaalsContact C-N 3.32Å; I225-D227 PolarHBondContact O-N 2.6Å; D227-K230 IonicContact OD1-NZ 3.91Å; D227-R231 WeakPolarHBondContact O-CD 3.34Å; D227-R231 VanDerWaalsContact O-CG 3.24Å; D227-R231 WeakPolarHBondContact O-CG 3.2Å; D227-R231 PolarHBondContact O-N 3.24Å
228	I	85.7	Confident	80.8	Confident	29 Å²	29	70.7 Å²	70.7	15%	0.149	32%	0.322	C	S	.	.	H	α-helix	trans	-64.5	-47.6	173.9	-64.6	152.9	0	0	0	109.7	L176 I177 K224 I225 E226 K230 R231 Q232	L176-I228 HydrophobicContact CD2-CD1 3.37Å; I177-I228 HydrophobicContact CD1-CG2 4.21Å; I177-I228 HydrophobicContact CG1-CG2 4.24Å; K224-I228 PolarHBondContact O-N 3.07Å; I225-I228 HydrophobicContact CD1-CD1 4Å; I225-I228 PolarHBondContact O-N 3.36Å; E226-I228 VanDerWaalsContact C-N 3.33Å; I228-K230 PolarHBondContact O-N 3.14Å; I228-R231 PolarHBondContact O-N 3.49Å; I228-Q232 WeakPolarHBondContact O-CG 3.44Å; I228-Q232 PolarHBondContact O-N 3.19Å
229	I	82.9	Confident	80.1	Confident	1 Å²	1	72.8 Å²	72.8	1%	0.005	33%	0.332	C	S	.	.	H	α-helix	trans	-57.5	-47.8	177.1	-75.4	170.6	0	0	0	111.3	I177 I225 E226 R231 Q232 I236 V240 Y244 L266	I177-I229 HydrophobicContact CD1-CG1 4.4Å; I225-I229 HydrophobicContact CG2-CD1 3.73Å; I225-I229 HydrophobicContact CG2-CG1 4.2Å; I225-I229 WeakPolarHBondContact O-CB 3.5Å; I225-I229 VanDerWaalsContact O-CG1 3.31Å; I225-I229 WeakPolarHBondContact O-CG1 3.29Å; I225-I229 PolarHBondContact O-N 2.93Å; E226-I229 PolarHBondContact O-N 3Å; I229-R231 PolarHBondContact O-N 3.49Å; I229-Q232 PolarHBondContact O-N 3.43Å; I229-Q232 VanDerWaalsContact O-N 3.09Å; I229-I236 HydrophobicContact CG2-CD1 3.26Å; I229-I236 HydrophobicContact CG2-CG1 4.41Å; I229-V240 HydrophobicContact CD1-CG1 3.58Å; I229-V240 HydrophobicContact CG1-CG1 4.45Å; I229-Y244 HydrophobicContact CD1-CD2 4.48Å; I229-Y244 HydrophobicContact CD1-CE2 3.57Å; I229-L266 HydrophobicContact CG2-CD1 4.03Å
230	K	82.4	Confident	79.6	Confident	80 Å²	80	72.9 Å²	72.9	35%	0.348	33%	0.333	S	S	.	.	H	α-helix	trans	-61.8	-29.6	-179.6	-72.3	168.1	-170.4	164.8	0	112.9	E226 D227 I228 L266 Y270	E226-K230 WeakPolarHBondContact O-CB 3.3Å; E226-K230 WeakPolarHBondContact O-CG 3.28Å; E226-K230 PolarHBondContact O-N 2.9Å; E226-K230 IonicContact OE2-NZ 4Å; D227-K230 IonicContact OD1-NZ 3.91Å; I228-K230 PolarHBondContact O-N 3.14Å; K230-L266 HydrophobicContact CG-CD1 4.11Å; K230-Y270 HydrophobicContact CB-CE1 4.23Å; K230-Y270 HydrophobicContact CG-CD2 4.32Å; K230-Y270 HydrophobicContact CG-CE1 4.22Å; K230-Y270 HydrophobicContact CG-CE2 3.78Å
231	R	81.7	Confident	78.6	Confident	207 Å²	207	75.6 Å²	75.6	78%	0.781	34%	0.343	S	S	*	.	H	α-helix	trans	-80.9	-19.2	178	-70.4	171.3	-171.7	-170.2	3.5	112.8	D227 I228 I229 K233	D227-R231 WeakPolarHBondContact O-CD 3.34Å; D227-R231 VanDerWaalsContact O-CG 3.24Å; D227-R231 WeakPolarHBondContact O-CG 3.2Å; D227-R231 PolarHBondContact O-N 3.24Å; I228-R231 PolarHBondContact O-N 3.49Å; I229-R231 PolarHBondContact O-N 3.49Å; R231-K233 PolarHBondContact O-N 3.29Å
232	Q	73.8	Confident	78	Confident	42 Å²	42	75 Å²	75	20%	0.196	34%	0.34	C	S	.	.			trans	-74.3	124.3	176.1	-69.8	-169	-2.8	0	0	110.2	N174 I228 I229 N234	N174-Q232 PolarHBondContact OD1-NE2 3.12Å; I228-Q232 WeakPolarHBondContact O-CG 3.44Å; I228-Q232 PolarHBondContact O-N 3.19Å; I229-Q232 PolarHBondContact O-N 3.43Å; I229-Q232 VanDerWaalsContact O-N 3.09Å; Q232-N234 VanDerWaalsContact C-N 3.28Å
233	K	63.2	Low	77.6	Confident	207 Å²	207	68 Å²	68	90%	0.9	31%	0.314	S	S	*	.			trans	-80.8	-8.6	176	-62.8	-173.6	179.6	-179.3	0	113.2	R231	R231-K233 PolarHBondContact O-N 3.29Å
234	N	57.2	Low	77.3	Confident	113 Å²	113	67 Å²	67	60%	0.604	31%	0.309	S	S	*	.	S	Bend	trans	-92.8	160	-170.1	-66.2	-10.7	0	0	0	112.3	Q232 I236	Q232-N234 VanDerWaalsContact C-N 3.28Å; N234-I236 PolarHBondContact O-N 3.44Å
235	K	61.7	Low	76.6	Confident	161 Å²	161	60.6 Å²	60.6	70%	0.7	28%	0.282	S	S	*	.	P	Polyproline II helix	trans	-54.1	123.2	168.8	-81.4	-175.8	177.8	-179.4	0	109.3
236	I	62.6	Low	76.1	Confident	25 Å²	25	60.5 Å²	60.5	13%	0.128	28%	0.281	C	S	.	.	P	Polyproline II helix	trans	-68.2	141.6	179.9	-66.8	-178.5	0	0	0	110.9	I229 N234 S238 V240 Y270 I271	I229-I236 HydrophobicContact CG2-CD1 3.26Å; I229-I236 HydrophobicContact CG2-CG1 4.41Å; N234-I236 PolarHBondContact O-N 3.44Å; I236-S238 PolarHBondContact O-N 2.94Å; I236-V240 HydrophobicContact CG2-CB 3.71Å; I236-V240 HydrophobicContact CG2-CG1 3.89Å; I236-V240 HydrophobicContact CG2-CG2 4.38Å; I236-Y270 VanDerWaalsContact CD1-C 3.45Å; I236-Y270 WeakPolarHBondContact CD1-O 3.41Å; I236-Y270 WeakPolarHBondContact CG1-O 2.97Å; I236-I271 HydrophobicContact CD1-CB 4.38Å; I236-I271 HydrophobicContact CD1-CG1 3.56Å; I236-I271 HydrophobicContact CG2-CG1 4.2Å; I236-I271 HydrophobicContact CG2-CG2 4.32Å
237	N	69.1	Low	76	Confident	74 Å²	74	59.8 Å²	59.8	40%	0.396	28%	0.278	S	S	.	.	P	Polyproline II helix	trans	-59.9	132.7	176.1	-169.3	-52.7	0	0	0	111.4	I181 H239 V240 R241	I181-N237 HydrophobicContact CD1-CB 3.84Å; N237-H239 PolarHBondContact O-N 3.32Å; N237-H239 WeakPolarHBondContact OD1-CB 3.47Å; N237-H239 PolarHBondContact OD1-CD2 3.37Å; N237-H239 VanDerWaalsContact OD1-CD2 3.24Å; N237-H239 PolarHBondContact OD1-N 2.93Å; N237-V240 HydrophobicContact CB-CG2 4.28Å; N237-V240 WeakPolarHBondContact O-CB 3.25Å; N237-V240 PolarHBondContact O-N 3.33Å; N237-R241 PolarHBondContact O-N 2.88Å
238	S	70.2	Confident	75.6	Confident	65 Å²	65	56.6 Å²	56.6	46%	0.455	26%	0.261	S	S	.	.	H	α-helix	trans	-55.6	-24.8	179.4	69.8	0	0	0	0	114.2	I236 R241 H242	I236-S238 PolarHBondContact O-N 2.94Å; S238-R241 WeakPolarHBondContact O-CB 3.47Å; S238-R241 PolarHBondContact O-N 2.82Å; S238-H242 PolarHBondContact O-N 3.04Å
239	H	77.4	Confident	75.3	Confident	64 Å²	64	56.4 Å²	56.4	30%	0.296	26%	0.261	S	S	.	.	H	α-helix	trans	-73.1	-35.1	175.4	-66.5	-60.5	0	0	0	113.4	I181 K185 N237 R241 H242 M243	I181-H239 HydrophobicContact CB-CB 4.48Å; I181-H239 HydrophobicContact CD1-CB 4.32Å; I181-H239 HydrophobicContact CG1-CB 4.05Å; I181-H239 HydrophobicContact CG2-CB 3.65Å; K185-H239 VanDerWaalsContact CE-CD2 3.48Å; K185-H239 WeakPolarHBondContact CE-CD2 3.39Å; K185-H239 WeakPolarHBondContact CE-CE1 3.29Å; K185-H239 WeakPolarHBondContact CE-NE2 3.35Å; K185-H239 PolarHBondContact NZ-NE2 3.04Å; K185-H239 VanDerWaalsContact NZ-NE2 3.11Å; N237-H239 PolarHBondContact O-N 3.32Å; N237-H239 WeakPolarHBondContact OD1-CB 3.47Å; N237-H239 PolarHBondContact OD1-CD2 3.37Å; N237-H239 VanDerWaalsContact OD1-CD2 3.24Å; N237-H239 PolarHBondContact OD1-N 2.93Å; H239-R241 VanDerWaalsContact C-N 3.29Å; H239-R241 PolarHBondContact O-N 3.06Å; H239-H242 WeakPolarHBondContact O-CB 3.14Å; H239-H242 PolarHBondContact O-N 2.84Å; H239-M243 WeakPolarHBondContact O-CB 3.4Å; H239-M243 PolarHBondContact O-N 3.4Å
240	V	81.6	Confident	75.3	Confident	2 Å²	2	57.3 Å²	57.3	1%	0.012	27%	0.265	C	S	.	.	H	α-helix	trans	-64.8	-39.8	173.3	176.8	0	0	0	0	109.6	I177 I181 I229 I236 N237 M243 Y244	I177-V240 HydrophobicContact CG2-CG2 3.87Å; I181-V240 HydrophobicContact CD1-CG2 3.95Å; I181-V240 HydrophobicContact CG1-CG2 4.01Å; I229-V240 HydrophobicContact CD1-CG1 3.58Å; I229-V240 HydrophobicContact CG1-CG1 4.45Å; I236-V240 HydrophobicContact CG2-CB 3.71Å; I236-V240 HydrophobicContact CG2-CG1 3.89Å; I236-V240 HydrophobicContact CG2-CG2 4.38Å; N237-V240 HydrophobicContact CB-CG2 4.28Å; N237-V240 WeakPolarHBondContact O-CB 3.25Å; N237-V240 PolarHBondContact O-N 3.33Å; V240-M243 HydrophobicContact CG1-CE 4.33Å; V240-M243 PolarHBondContact O-N 3.45Å; V240-Y244 HydrophobicContact CG1-CD2 3.93Å; V240-Y244 HydrophobicContact CG1-CE2 3.96Å; V240-Y244 WeakPolarHBondContact O-CD2 3.43Å; V240-Y244 PolarHBondContact O-N 3.44Å; V240-Y244 VanDerWaalsContact O-N 3.11Å
241	R	72.4	Confident	75.4	Confident	60 Å²	60	53.5 Å²	53.5	23%	0.226	25%	0.248	C	C	.	.	H	α-helix	trans	-57.3	-51.6	171.7	-174.3	173.2	59.7	-172.9	-2.6	111.9	N237 S238 H239 M243 Y244 C245 L267 I271	N237-R241 PolarHBondContact O-N 2.88Å; S238-R241 WeakPolarHBondContact O-CB 3.47Å; S238-R241 PolarHBondContact O-N 2.82Å; H239-R241 VanDerWaalsContact C-N 3.29Å; H239-R241 PolarHBondContact O-N 3.06Å; R241-M243 VanDerWaalsContact C-N 3.3Å; R241-M243 PolarHBondContact O-N 3.24Å; R241-Y244 PolarHBondContact O-N 3.3Å; R241-C245 WeakPolarHBondContact O-CB 3.49Å; R241-C245 PolarHBondContact O-N 3.35Å; R241-C245 PolarHBondContact O-SG 3.37Å; R241-C245 VanDerWaalsContact O-SG 3.35Å; R241-L267 HydrophobicContact CG-CD2 4.3Å; R241-I271 HydrophobicContact CB-CG2 3.19Å; R241-I271 HydrophobicContact CG-CG2 3.37Å
242	H	78.6	Confident	75.2	Confident	48 Å²	48	45.3 Å²	45.3	22%	0.222	22%	0.223	C	C	.	.	H	α-helix	trans	-56.2	-48.9	179.2	178.6	-79.2	0	0	0	110.3	W184 S238 H239 Y244 C245 T246	W184-H242 AromaticContact CE2-ND1 3.91Å; W184-H242 AromaticContact CZ2-ND1 3.84Å; W184-H242 AromaticContact NE1-ND1 3.35Å; W184-H242 PolarHBondContact NE1-ND1 3.07Å; S238-H242 PolarHBondContact O-N 3.04Å; H239-H242 WeakPolarHBondContact O-CB 3.14Å; H239-H242 PolarHBondContact O-N 2.84Å; H242-Y244 PolarHBondContact O-N 3.19Å; H242-C245 PolarHBondContact O-N 3.41Å; H242-T246 PolarHBondContact CE1-OG1 3.31Å; H242-T246 VanDerWaalsContact CE1-OG1 3.22Å; H242-T246 PolarHBondContact ND1-OG1 3.48Å; H242-T246 WeakPolarHBondContact O-CB 3.41Å; H242-T246 PolarHBondContact O-N 3.27Å; H242-T246 PolarHBondContact O-OG1 3.31Å
243	M	84.4	Confident	75.3	Confident	3 Å²	3	49.9 Å²	49.9	2%	0.015	25%	0.249	C	C	.	.	H	α-helix	trans	-53.4	-55.3	179.2	180	175.1	68.2	0	0	113.2	L180 W184 F215 L220 H239 V240 R241 C245 T246 I247	L180-M243 HydrophobicContact CD2-CE 3.98Å; L180-M243 HydrophobicContact CG-CE 4.43Å; L180-M243 HydrophobicContact CG-SD 4.39Å; W184-M243 HydrophobicContact CB-SD 3.99Å; W184-M243 HydrophobicContact CD2-CB 3.74Å; W184-M243 HydrophobicContact CD2-CG 3.51Å; W184-M243 HydrophobicContact CD2-SD 4Å; W184-M243 VanDerWaalsContact CE2-CA 3.5Å; W184-M243 HydrophobicContact CE3-CB 4.36Å; W184-M243 HydrophobicContact CE3-CG 3.66Å; W184-M243 HydrophobicContact CE3-SD 4.13Å; W184-M243 HydrophobicContact CG-CB 3.92Å; W184-M243 HydrophobicContact CG-CG 3.92Å; W184-M243 HydrophobicContact CG-SD 3.91Å; W184-M243 HydrophobicContact CH2-CG 4.36Å; W184-M243 HydrophobicContact CZ2-CB 4.15Å; W184-M243 HydrophobicContact CZ2-CG 4.28Å; W184-M243 HydrophobicContact CZ3-CG 4.08Å; F215-M243 HydrophobicContact CE1-SD 3.84Å; F215-M243 HydrophobicContact CZ-SD 4.45Å; L220-M243 HydrophobicContact CD1-CE 4.25Å; L220-M243 HydrophobicContact CD1-CG 4.47Å; L220-M243 HydrophobicContact CD1-SD 4.35Å; L220-M243 HydrophobicContact CD2-CE 3.73Å; L220-M243 HydrophobicContact CD2-SD 3.93Å; H239-M243 WeakPolarHBondContact O-CB 3.4Å; H239-M243 PolarHBondContact O-N 3.4Å; V240-M243 HydrophobicContact CG1-CE 4.33Å; V240-M243 PolarHBondContact O-N 3.45Å; R241-M243 VanDerWaalsContact C-N 3.3Å; R241-M243 PolarHBondContact O-N 3.24Å; M243-C245 VanDerWaalsContact C-N 3.35Å; M243-C245 PolarHBondContact O-N 3.23Å; M243-T246 PolarHBondContact O-N 3.14Å; M243-I247 HydrophobicContact CG-CD1 3.94Å; M243-I247 WeakPolarHBondContact O-CG1 3.33Å; M243-I247 PolarHBondContact O-N 2.85Å
244	Y	83.3	Confident	76	Confident	1 Å²	1	47 Å²	47	0%	0.004	23%	0.232	C	C	.	.	H	α-helix	trans	-64.8	-38.5	179.5	-83.2	-75.2	0	0	0	112.5	L220 I229 V240 R241 H242 L248 Y263 L266 I271	L220-Y244 HydrophobicContact CD1-CE1 3.96Å; I229-Y244 HydrophobicContact CD1-CD2 4.48Å; I229-Y244 HydrophobicContact CD1-CE2 3.57Å; V240-Y244 HydrophobicContact CG1-CD2 3.93Å; V240-Y244 HydrophobicContact CG1-CE2 3.96Å; V240-Y244 WeakPolarHBondContact O-CD2 3.43Å; V240-Y244 PolarHBondContact O-N 3.44Å; V240-Y244 VanDerWaalsContact O-N 3.11Å; R241-Y244 PolarHBondContact O-N 3.3Å; H242-Y244 PolarHBondContact O-N 3.19Å; Y244-L248 WeakPolarHBondContact O-CB 3.37Å; Y244-L248 WeakPolarHBondContact O-CD1 3.32Å; Y244-L248 WeakPolarHBondContact O-CG 3.38Å; Y244-L248 PolarHBondContact O-N 2.92Å; Y244-Y263 AromaticContact CD1-CD1 3.66Å; Y244-Y263 HydrophobicContact CD1-CD1 3.66Å; Y244-Y263 AromaticContact CD1-CE1 3.91Å; Y244-Y263 HydrophobicContact CD1-CE1 3.91Å; Y244-Y263 AromaticContact CE1-CD1 3.69Å; Y244-Y263 HydrophobicContact CE1-CD1 3.69Å; Y244-Y263 AromaticContact CE1-CE1 3.5Å; Y244-Y263 HydrophobicContact CE1-CE1 3.5Å; Y244-L266 HydrophobicContact CD1-CD2 4.31Å; Y244-L266 HydrophobicContact CD2-CD2 4.38Å; Y244-L266 HydrophobicContact CE1-CD2 3.99Å; Y244-L266 HydrophobicContact CE2-CD2 4.07Å; Y244-L266 HydrophobicContact CG-CD2 4.49Å; Y244-I271 HydrophobicContact CD2-CD1 4.17Å
245	C	75.9	Confident	77.1	Confident	4 Å²	4	42.8 Å²	42.8	3%	0.027	21%	0.21	C	C	.	.	H	α-helix	trans	-63.3	-43.7	175.7	-74.6	0	0	0	0	111.9	H8 R241 H242 M243 L248 T249	H8-C245 VanDerWaalsContact CD2-SG 3.58Å; R241-C245 WeakPolarHBondContact O-CB 3.49Å; R241-C245 PolarHBondContact O-N 3.35Å; R241-C245 PolarHBondContact O-SG 3.37Å; R241-C245 VanDerWaalsContact O-SG 3.35Å; H242-C245 PolarHBondContact O-N 3.41Å; M243-C245 VanDerWaalsContact C-N 3.35Å; M243-C245 PolarHBondContact O-N 3.23Å; C245-L248 PolarHBondContact O-N 3.01Å; C245-T249 PolarHBondContact O-N 3.23Å; C245-T249 PolarHBondContact O-OG1 3.36Å
246	T	80.2	Confident	78.1	Confident	0 Å²	0	38.1 Å²	38.1	0%	0	20%	0.197	C	C	.	.	H	α-helix	trans	-62.7	-49.6	177	-54.8	0	0	0	0	111.8	V12 W184 I188 H242 M243 L248 T249 F250	V12-T246 HydrophobicContact CG1-CG2 3.97Å; V12-T246 WeakPolarHBondContact CG1-OG1 3.41Å; W184-T246 HydrophobicContact CH2-CG2 3.84Å; W184-T246 HydrophobicContact CZ2-CG2 3.96Å; I188-T246 HydrophobicContact CD1-CG2 3.87Å; I188-T246 HydrophobicContact CG1-CG2 4.41Å; H242-T246 PolarHBondContact CE1-OG1 3.31Å; H242-T246 VanDerWaalsContact CE1-OG1 3.22Å; H242-T246 PolarHBondContact ND1-OG1 3.48Å; H242-T246 WeakPolarHBondContact O-CB 3.41Å; H242-T246 PolarHBondContact O-N 3.27Å; H242-T246 PolarHBondContact O-OG1 3.31Å; M243-T246 PolarHBondContact O-N 3.14Å; T246-L248 VanDerWaalsContact C-N 3.3Å; T246-L248 PolarHBondContact O-N 3.43Å; T246-T249 WeakPolarHBondContact O-CB 3.27Å; T246-T249 PolarHBondContact O-N 2.9Å; T246-T249 VanDerWaalsContact O-N 3.1Å; T246-F250 HydrophobicContact CG2-CD2 4.14Å; T246-F250 HydrophobicContact CG2-CE1 4.21Å; T246-F250 HydrophobicContact CG2-CE2 3.58Å; T246-F250 HydrophobicContact CG2-CZ 3.61Å; T246-F250 WeakPolarHBondContact O-CG 3.44Å; T246-F250 PolarHBondContact O-N 3.23Å
247	I	84.9	Confident	78.8	Confident	2 Å²	2	41.6 Å²	41.6	1%	0.01	22%	0.219	C	C	.	.	H	α-helix	trans	-59.9	-43.4	179.1	-70.7	170.9	0	0	0	110.5	W184 F215 L216 L220 M243 T249 F250 C251	W184-I247 HydrophobicContact CH2-CG1 4.26Å; W184-I247 HydrophobicContact CZ3-CD1 4.32Å; W184-I247 HydrophobicContact CZ3-CG1 4.25Å; F215-I247 HydrophobicContact CD1-CD1 3.94Å; L216-I247 HydrophobicContact CB-CG2 3.88Å; L216-I247 HydrophobicContact CD1-CG2 4.15Å; L216-I247 HydrophobicContact CD2-CG2 3.95Å; L216-I247 HydrophobicContact CG-CG2 4.22Å; L220-I247 HydrophobicContact CD1-CD1 3.38Å; L220-I247 HydrophobicContact CG-CD1 4.45Å; M243-I247 HydrophobicContact CG-CD1 3.94Å; M243-I247 WeakPolarHBondContact O-CG1 3.33Å; M243-I247 PolarHBondContact O-N 2.85Å; I247-T249 VanDerWaalsContact C-N 3.33Å; I247-T249 PolarHBondContact O-N 3.46Å; I247-F250 PolarHBondContact O-N 3.03Å; I247-C251 VanDerWaalsContact O-CB 3.27Å; I247-C251 WeakPolarHBondContact O-CB 3.41Å; I247-C251 PolarHBondContact O-N 3.01Å; I247-C251 PolarHBondContact O-SG 2.61Å
248	L	78.8	Confident	79.5	Confident	1 Å²	1	43.7 Å²	43.7	1%	0.005	23%	0.231	C	C	.	.	H	α-helix	trans	-65	-36.3	176.3	-72.4	167.8	0	0	0	112.7	Y244 C245 T246 F250 C251 S252 L255 Y263 L267	Y244-L248 WeakPolarHBondContact O-CB 3.37Å; Y244-L248 WeakPolarHBondContact O-CD1 3.32Å; Y244-L248 WeakPolarHBondContact O-CG 3.38Å; Y244-L248 PolarHBondContact O-N 2.92Å; C245-L248 PolarHBondContact O-N 3.01Å; T246-L248 VanDerWaalsContact C-N 3.3Å; T246-L248 PolarHBondContact O-N 3.43Å; L248-F250 VanDerWaalsContact C-N 3.34Å; L248-C251 PolarHBondContact O-N 3.31Å; L248-S252 WeakPolarHBondContact O-CA 3.43Å; L248-S252 WeakPolarHBondContact O-CB 3.48Å; L248-S252 PolarHBondContact O-N 3.06Å; L248-S252 PolarHBondContact O-OG 2.9Å; L248-L255 HydrophobicContact CD2-CD1 4.1Å; L248-Y263 HydrophobicContact CD1-CG 4.38Å; L248-Y263 HydrophobicContact CD2-CD2 3.69Å; L248-Y263 HydrophobicContact CD2-CG 3.86Å; L248-Y263 HydrophobicContact CG-CG 4.43Å; L248-L267 HydrophobicContact CD1-CD1 3.49Å; L248-L267 VanDerWaalsContact CD1-CD1 3.49Å
249	T	78.6	Confident	80	Confident	25 Å²	25	44 Å²	44	15%	0.153	22%	0.224	C	C	.	.	H	α-helix	trans	-60.4	-46.9	173.3	-60.3	0	0	0	0	110.5	R9 Q13 C245 T246 I247 S252	R9-T249 WeakPolarHBondContact CB-OG1 3.39Å; R9-T249 WeakPolarHBondContact CG-OG1 3.36Å; Q13-T249 HydrophobicContact CB-CG2 4.21Å; C245-T249 PolarHBondContact O-N 3.23Å; C245-T249 PolarHBondContact O-OG1 3.36Å; T246-T249 WeakPolarHBondContact O-CB 3.27Å; T246-T249 PolarHBondContact O-N 2.9Å; T246-T249 VanDerWaalsContact O-N 3.1Å; I247-T249 VanDerWaalsContact C-N 3.33Å; I247-T249 PolarHBondContact O-N 3.46Å; T249-S252 PolarHBondContact O-OG 3.04Å
250	F	83.6	Confident	79.9	Confident	19 Å²	19	42.4 Å²	42.4	8%	0.083	22%	0.217	C	C	.	.	H	α-helix	trans	-69.9	-32.4	-179.3	-64.3	-13.7	0	0	0	113.6	T16 I188 Y192 E208 T246 I247 L248	T16-F250 HydrophobicContact CG2-CZ 4.28Å; I188-F250 HydrophobicContact CD1-CE2 4.14Å; I188-F250 HydrophobicContact CD1-CZ 4.34Å; Y192-F250 HydrophobicContact CD2-CE2 4.07Å; Y192-F250 HydrophobicContact CD2-CZ 4.36Å; Y192-F250 HydrophobicContact CE1-CZ 4.24Å; Y192-F250 HydrophobicContact CE2-CE1 4.46Å; Y192-F250 AromaticContact CE2-CE2 3.56Å; Y192-F250 HydrophobicContact CE2-CE2 3.56Å; Y192-F250 AromaticContact CE2-CZ 3.54Å; Y192-F250 HydrophobicContact CE2-CZ 3.54Å; Y192-F250 AromaticContact CZ-CZ 3.47Å; Y192-F250 VanDerWaalsContact CZ-CZ 3.47Å; Y192-F250 WeakPolarHBondContact OH-CZ 3.46Å; E208-F250 HydrophobicContact CB-CB 4.42Å; E208-F250 HydrophobicContact CB-CD1 3.98Å; E208-F250 HydrophobicContact CB-CE1 4.35Å; E208-F250 HydrophobicContact CB-CG 4.08Å; E208-F250 HydrophobicContact CG-CD1 4.26Å; E208-F250 HydrophobicContact CG-CE1 4.15Å; T246-F250 HydrophobicContact CG2-CD2 4.14Å; T246-F250 HydrophobicContact CG2-CE1 4.21Å; T246-F250 HydrophobicContact CG2-CE2 3.58Å; T246-F250 HydrophobicContact CG2-CZ 3.61Å; T246-F250 WeakPolarHBondContact O-CG 3.44Å; T246-F250 PolarHBondContact O-N 3.23Å; I247-F250 PolarHBondContact O-N 3.03Å; L248-F250 VanDerWaalsContact C-N 3.34Å
251	C	84.4	Confident	79.8	Confident	0 Å²	0	47 Å²	47	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-105	-9.6	-171.1	-57.3	0	0	0	0	114.4	Y209 V213 I247 L248 D253 R254 L255	Y209-C251 HydrophobicContact CD2-CB 4.43Å; Y209-C251 HydrophobicContact CE2-CB 4.43Å; V213-C251 PolarHBondContact N-SG 2.81Å; I247-C251 VanDerWaalsContact O-CB 3.27Å; I247-C251 WeakPolarHBondContact O-CB 3.41Å; I247-C251 PolarHBondContact O-N 3.01Å; I247-C251 PolarHBondContact O-SG 2.61Å; L248-C251 PolarHBondContact O-N 3.31Å; C251-D253 VanDerWaalsContact C-N 3.29Å; C251-D253 PolarHBondContact O-N 2.7Å; C251-R254 PolarHBondContact O-N 3.19Å; C251-L255 HydrophobicContact CB-CD1 3.52Å; C251-L255 HydrophobicContact CB-CG 3.73Å; C251-L255 WeakPolarHBondContact O-CG 3.48Å; C251-L255 PolarHBondContact O-N 3.17Å
252	S	76.6	Confident	80.3	Confident	36 Å²	36	48.1 Å²	48.1	25%	0.252	25%	0.246	S	C	.	.	T	Hydrogen-bonded Turn	trans	-54.1	-39.8	-171.5	49.8	0	0	0	0	114.4	L248 T249 R254 I260	L248-S252 WeakPolarHBondContact O-CA 3.43Å; L248-S252 WeakPolarHBondContact O-CB 3.48Å; L248-S252 PolarHBondContact O-N 3.06Å; L248-S252 PolarHBondContact O-OG 2.9Å; T249-S252 PolarHBondContact O-OG 3.04Å; S252-R254 PolarHBondContact O-N 3.18Å; S252-I260 WeakPolarHBondContact O-CD1 3.48Å
253	D	76	Confident	80.4	Confident	137 Å²	137	46 Å²	46	73%	0.733	24%	0.237	S	C	*	.	T	Hydrogen-bonded Turn	trans	-69.2	-14.9	-177.6	-65	-20.1	0	0	0	113.5	C251	C251-D253 VanDerWaalsContact C-N 3.29Å; C251-D253 PolarHBondContact O-N 2.7Å
254	R	79.3	Confident	79.9	Confident	146 Å²	146	47.2 Å²	47.2	55%	0.551	24%	0.243	S	C	*	.	T	Hydrogen-bonded Turn	trans	-127	-8.4	-173.2	-62.9	-172	-176.4	-170.7	-0.1	114.3	Y209 C251 S252	Y209-R254 HydrophobicContact CD2-CB 4.03Å; Y209-R254 HydrophobicContact CD2-CG 4.17Å; Y209-R254 HydrophobicContact CE2-CB 3.42Å; Y209-R254 VanDerWaalsContact CE2-CB 3.42Å; Y209-R254 HydrophobicContact CE2-CG 3.97Å; Y209-R254 VanDerWaalsContact CZ-CD 3.47Å; C251-R254 PolarHBondContact O-N 3.19Å; S252-R254 PolarHBondContact O-N 3.18Å
255	L	79.7	Confident	79.7	Confident	25 Å²	25	52 Å²	52	13%	0.131	27%	0.265	C	S	.	.	S	Bend	trans	-78.3	148.1	171.8	-74.5	173.5	0	0	0	110.5	L216 L248 C251 K259 I260	L216-L255 HydrophobicContact CD2-CD1 4.38Å; L216-L255 HydrophobicContact CD2-CD2 4.25Å; L248-L255 HydrophobicContact CD2-CD1 4.1Å; C251-L255 HydrophobicContact CB-CD1 3.52Å; C251-L255 HydrophobicContact CB-CG 3.73Å; C251-L255 WeakPolarHBondContact O-CG 3.48Å; C251-L255 PolarHBondContact O-N 3.17Å; L255-K259 HydrophobicContact CD2-CD 3.98Å; L255-I260 HydrophobicContact CB-CD1 4.14Å; L255-I260 HydrophobicContact CB-CG1 3.77Å
256	S	82.4	Confident	79.9	Confident	63 Å²	63	52 Å²	52	44%	0.441	27%	0.265	S	S	.	.			trans	-62.8	150.1	171.2	67	0	0	0	0	110.7	D258 K259 I260	S256-D258 PolarHBondContact O-N 3.08Å; S256-K259 PolarHBondContact O-N 3.21Å; S256-K259 VanDerWaalsContact O-N 3.1Å; S256-K259 PolarHBondContact OG-N 2.82Å; S256-I260 WeakPolarHBondContact O-CG1 3.42Å; S256-I260 PolarHBondContact O-N 2.96Å
257	V	78.3	Confident	79.4	Confident	98 Å²	98	52 Å²	52	59%	0.594	27%	0.265	S	S	*	.	H	α-helix	trans	-54.4	-41.1	177.7	177.9	0	0	0	0	110.7	K259 I260 Q261	V257-K259 PolarHBondContact O-N 2.93Å; V257-I260 PolarHBondContact O-N 3.19Å; V257-Q261 HydrophobicContact CG1-CG 4.37Å; V257-Q261 WeakPolarHBondContact O-CB 3.32Å; V257-Q261 WeakPolarHBondContact O-CG 3.44Å; V257-Q261 PolarHBondContact O-N 3.39Å
258	D	82.2	Confident	78.7	Confident	118 Å²	118	54.3 Å²	54.3	63%	0.631	28%	0.276	S	S	*	.	H	α-helix	trans	-62.4	-43.7	178.6	-60.4	-28.6	0	0	0	112.5	S256 Q261 Q262	S256-D258 PolarHBondContact O-N 3.08Å; D258-Q261 PolarHBondContact O-N 3.17Å; D258-Q262 WeakPolarHBondContact O-CB 3.42Å; D258-Q262 PolarHBondContact O-N 2.88Å
259	K	80.8	Confident	78.3	Confident	71 Å²	71	60.6 Å²	60.6	31%	0.309	30%	0.304	S	S	.	.	H	α-helix	trans	-63	-44.3	175.7	-81.1	-165	174.6	-162.9	0	111	E221 L255 S256 V257 Q261 Q262 Y263	E221-K259 IonicContact OE1-NZ 2.7Å; E221-K259 PolarHBondContact OE1-NZ 2.97Å; E221-K259 IonicContact OE2-NZ 3.9Å; L255-K259 HydrophobicContact CD2-CD 3.98Å; S256-K259 PolarHBondContact O-N 3.21Å; S256-K259 VanDerWaalsContact O-N 3.1Å; S256-K259 PolarHBondContact OG-N 2.82Å; V257-K259 PolarHBondContact O-N 2.93Å; K259-Q261 VanDerWaalsContact C-N 3.29Å; K259-Q261 PolarHBondContact O-N 3.07Å; K259-Q262 WeakPolarHBondContact O-CB 3.28Å; K259-Q262 PolarHBondContact O-N 3.24Å; K259-Y263 HydrophobicContact CB-CE2 4.41Å; K259-Y263 WeakPolarHBondContact O-CD2 3.33Å; K259-Y263 PolarHBondContact O-N 3.27Å
260	I	76.3	Confident	77.6	Confident	31 Å²	31	63.6 Å²	63.6	16%	0.159	31%	0.313	C	S	.	.	H	α-helix	trans	-60.7	-42.6	177.2	-63.8	168.6	0	0	0	110.4	S252 L255 S256 V257 Y263 N264	S252-I260 WeakPolarHBondContact O-CD1 3.48Å; L255-I260 HydrophobicContact CB-CD1 4.14Å; L255-I260 HydrophobicContact CB-CG1 3.77Å; S256-I260 WeakPolarHBondContact O-CG1 3.42Å; S256-I260 PolarHBondContact O-N 2.96Å; V257-I260 PolarHBondContact O-N 3.19Å; I260-Y263 PolarHBondContact O-N 3.38Å; I260-N264 WeakPolarHBondContact O-CB 3.21Å; I260-N264 PolarHBondContact O-N 2.87Å; I260-N264 PolarHBondContact O-ND2 3.29Å
261	Q	78.6	Confident	76.4	Confident	100 Å²	100	63.3 Å²	63.3	47%	0.467	31%	0.312	S	S	.	.	H	α-helix	trans	-63.6	-44.7	176.1	-73.8	-178.6	10.4	0	0	111.9	V257 D258 K259 Y263 N264 Q265	V257-Q261 HydrophobicContact CG1-CG 4.37Å; V257-Q261 WeakPolarHBondContact O-CB 3.32Å; V257-Q261 WeakPolarHBondContact O-CG 3.44Å; V257-Q261 PolarHBondContact O-N 3.39Å; D258-Q261 PolarHBondContact O-N 3.17Å; K259-Q261 VanDerWaalsContact C-N 3.29Å; K259-Q261 PolarHBondContact O-N 3.07Å; Q261-Y263 PolarHBondContact O-N 3.26Å; Q261-N264 PolarHBondContact O-N 3.32Å; Q261-Q265 WeakPolarHBondContact O-CB 2.94Å; Q261-Q265 VanDerWaalsContact O-CG 3.32Å; Q261-Q265 WeakPolarHBondContact O-CG 3.29Å; Q261-Q265 PolarHBondContact O-N 3.38Å
262	Q	83.6	Confident	75.2	Confident	83 Å²	83	64.2 Å²	64.2	39%	0.388	32%	0.317	S	S	.	.	H	α-helix	trans	-56.5	-48.5	175.5	176.7	179.1	-8.4	0	0	111.4	E226 D258 K259 Q265 L266	E226-Q262 PolarHBondContact OE2-NE2 2.87Å; D258-Q262 WeakPolarHBondContact O-CB 3.42Å; D258-Q262 PolarHBondContact O-N 2.88Å; K259-Q262 WeakPolarHBondContact O-CB 3.28Å; K259-Q262 PolarHBondContact O-N 3.24Å; Q262-Q265 PolarHBondContact O-N 3.1Å; Q262-L266 PolarHBondContact O-N 3.21Å
263	Y	80.3	Confident	74	Confident	4 Å²	4	67 Å²	67	2%	0.016	33%	0.334	C	S	.	.	H	α-helix	trans	-67.9	-37.8	177.9	-73.6	-58.3	0	0	0	113.2	L216 E226 Y244 L248 K259 I260 Q261 Q265 L266 L267	L216-Y263 HydrophobicContact CD1-CE1 4.36Å; L216-Y263 HydrophobicContact CD1-CE2 4.42Å; L216-Y263 WeakPolarHBondContact CD1-OH 3.35Å; L216-Y263 HydrophobicContact CD2-CE2 4.37Å; E226-Y263 HydrophobicContact CG-CE1 4.29Å; E226-Y263 WeakPolarHBondContact OE1-CE1 3.46Å; E226-Y263 PolarHBondContact OE1-OH 3.32Å; Y244-Y263 AromaticContact CD1-CD1 3.66Å; Y244-Y263 HydrophobicContact CD1-CD1 3.66Å; Y244-Y263 AromaticContact CD1-CE1 3.91Å; Y244-Y263 HydrophobicContact CD1-CE1 3.91Å; Y244-Y263 AromaticContact CE1-CD1 3.69Å; Y244-Y263 HydrophobicContact CE1-CD1 3.69Å; Y244-Y263 AromaticContact CE1-CE1 3.5Å; Y244-Y263 HydrophobicContact CE1-CE1 3.5Å; L248-Y263 HydrophobicContact CD1-CG 4.38Å; L248-Y263 HydrophobicContact CD2-CD2 3.69Å; L248-Y263 HydrophobicContact CD2-CG 3.86Å; L248-Y263 HydrophobicContact CG-CG 4.43Å; K259-Y263 HydrophobicContact CB-CE2 4.41Å; K259-Y263 WeakPolarHBondContact O-CD2 3.33Å; K259-Y263 PolarHBondContact O-N 3.27Å; I260-Y263 PolarHBondContact O-N 3.38Å; Q261-Y263 PolarHBondContact O-N 3.26Å; Y263-Q265 VanDerWaalsContact C-N 3.31Å; Y263-Q265 PolarHBondContact O-N 3.14Å; Y263-L266 HydrophobicContact CD1-CD2 4.46Å; Y263-L266 WeakPolarHBondContact O-CB 3.44Å; Y263-L266 PolarHBondContact O-N 3.19Å; Y263-L267 WeakPolarHBondContact O-CB 3.3Å; Y263-L267 WeakPolarHBondContact O-CG 3.27Å; Y263-L267 PolarHBondContact O-N 3.24Å
264	N	74.2	Confident	72.7	Confident	27 Å²	27	62.2 Å²	62.2	14%	0.144	32%	0.317	C	S	.	.	H	α-helix	trans	-61.7	-42.3	172.6	-76.1	-21.3	0	0	0	110.6	R9 I260 Q261 L267 M268	R9-N264 PolarHBondContact NH2-OD1 3.23Å; I260-N264 WeakPolarHBondContact O-CB 3.21Å; I260-N264 PolarHBondContact O-N 2.87Å; I260-N264 PolarHBondContact O-ND2 3.29Å; Q261-N264 PolarHBondContact O-N 3.32Å; N264-L267 PolarHBondContact O-N 2.82Å; N264-M268 VanDerWaalsContact O-CB 3.24Å; N264-M268 WeakPolarHBondContact O-CB 3.42Å; N264-M268 WeakPolarHBondContact O-CG 3.2Å; N264-M268 PolarHBondContact O-N 3.22Å
265	Q	79.7	Confident	71	Confident	103 Å²	103	58.9 Å²	58.9	48%	0.481	31%	0.309	S	S	.	.	H	α-helix	trans	-64.3	-40.5	175.4	-72.9	-178.7	15	0	0	111.8	Q261 Q262 Y263 M268 K269	Q261-Q265 WeakPolarHBondContact O-CB 2.94Å; Q261-Q265 VanDerWaalsContact O-CG 3.32Å; Q261-Q265 WeakPolarHBondContact O-CG 3.29Å; Q261-Q265 PolarHBondContact O-N 3.38Å; Q262-Q265 PolarHBondContact O-N 3.1Å; Y263-Q265 VanDerWaalsContact C-N 3.31Å; Y263-Q265 PolarHBondContact O-N 3.14Å; Q265-M268 PolarHBondContact O-N 2.8Å; Q265-K269 VanDerWaalsContact O-CB 3.28Å; Q265-K269 WeakPolarHBondContact O-CB 3.42Å; Q265-K269 WeakPolarHBondContact O-CG 3.36Å; Q265-K269 PolarHBondContact O-N 2.89Å
266	L	78.6	Confident	69.1	Low	3 Å²	3	65.3 Å²	65.3	2%	0.016	34%	0.338	C	S	.	.	H	α-helix	trans	-58.2	-49.7	173.5	-172.9	77.7	0	0	0	110.6	E226 I229 K230 Y244 Q262 Y263 M268 Y270 I271	E226-L266 HydrophobicContact CB-CD1 4.36Å; E226-L266 HydrophobicContact CB-CD2 4.46Å; E226-L266 HydrophobicContact CG-CD2 3.92Å; I229-L266 HydrophobicContact CG2-CD1 4.03Å; K230-L266 HydrophobicContact CG-CD1 4.11Å; Y244-L266 HydrophobicContact CD1-CD2 4.31Å; Y244-L266 HydrophobicContact CD2-CD2 4.38Å; Y244-L266 HydrophobicContact CE1-CD2 3.99Å; Y244-L266 HydrophobicContact CE2-CD2 4.07Å; Y244-L266 HydrophobicContact CG-CD2 4.49Å; Q262-L266 PolarHBondContact O-N 3.21Å; Y263-L266 HydrophobicContact CD1-CD2 4.46Å; Y263-L266 WeakPolarHBondContact O-CB 3.44Å; Y263-L266 PolarHBondContact O-N 3.19Å; L266-M268 VanDerWaalsContact C-N 3.33Å; L266-M268 PolarHBondContact O-N 2.89Å; L266-Y270 HydrophobicContact CD1-CD2 4Å; L266-Y270 WeakPolarHBondContact O-CB 3.34Å; L266-Y270 PolarHBondContact O-N 2.87Å; L266-I271 HydrophobicContact CD2-CD1 4.35Å; L266-I271 HydrophobicContact CG-CD1 4.25Å; L266-I271 PolarHBondContact O-N 3.25Å
267	L	70.9	Confident	67.1	Low	1 Å²	1	68.5 Å²	68.5	1%	0.005	34%	0.344	C	S	.	.	I	π-helix	trans	-58.5	-45.3	177.2	-76.9	166.8	0	0	0	111.6	I5 R241 L248 Y263 N264 I271 L272	I5-L267 HydrophobicContact CD1-CB 4.45Å; R241-L267 HydrophobicContact CG-CD2 4.3Å; L248-L267 HydrophobicContact CD1-CD1 3.49Å; L248-L267 VanDerWaalsContact CD1-CD1 3.49Å; Y263-L267 WeakPolarHBondContact O-CB 3.3Å; Y263-L267 WeakPolarHBondContact O-CG 3.27Å; Y263-L267 PolarHBondContact O-N 3.24Å; N264-L267 PolarHBondContact O-N 2.82Å; L267-I271 HydrophobicContact CD2-CB 4.17Å; L267-I271 HydrophobicContact CD2-CD1 3.59Å; L267-I271 HydrophobicContact CD2-CG1 4.39Å; L267-I271 HydrophobicContact CD2-CG2 4.09Å; L267-I271 HydrophobicContact CG-CD1 4.16Å; L267-I271 CarbonylContact O-C 3.47Å; L267-I271 WeakPolarHBondContact O-CA 3.41Å; L267-I271 VanDerWaalsContact O-CB 3.31Å; L267-I271 WeakPolarHBondContact O-CB 3.35Å; L267-I271 PolarHBondContact O-N 3.48Å; L267-I271 VanDerWaalsContact O-N 3.12Å; L267-L272 WeakPolarHBondContact O-CB 3.42Å; L267-L272 WeakPolarHBondContact O-CG 3.48Å; L267-L272 PolarHBondContact O-N 2.88Å
268	M	70.4	Confident	64.9	Low	49 Å²	49	70.5 Å²	70.5	24%	0.241	35%	0.352	C	S	.	.	I	π-helix	trans	-70.7	-47	-176.3	-71.3	-79.4	-67	0	0	113.3	M1 I5 N264 Q265 L266 L272 P273	M1-M268 HydrophobicContact CB-CE 3.68Å; M1-M268 HydrophobicContact CB-SD 4.03Å; M1-M268 HydrophobicContact CG-CE 3.49Å; M1-M268 VanDerWaalsContact CG-CE 3.49Å; M1-M268 HydrophobicContact CG-SD 3.53Å; M1-M268 VanDerWaalsContact CG-SD 3.53Å; M1-M268 HydrophobicContact SD-CE 3.12Å; M1-M268 WeakPolarHBondContact SD-CE 3.25Å; M1-M268 HydrophobicContact SD-SD 3.7Å; I5-M268 HydrophobicContact CD1-CG 3.66Å; I5-M268 HydrophobicContact CD1-SD 3.6Å; I5-M268 HydrophobicContact CG1-SD 4.42Å; N264-M268 VanDerWaalsContact O-CB 3.24Å; N264-M268 WeakPolarHBondContact O-CB 3.42Å; N264-M268 WeakPolarHBondContact O-CG 3.2Å; N264-M268 PolarHBondContact O-N 3.22Å; Q265-M268 PolarHBondContact O-N 2.8Å; L266-M268 VanDerWaalsContact C-N 3.33Å; L266-M268 PolarHBondContact O-N 2.89Å; M268-L272 HydrophobicContact SD-CD1 3.98Å; M268-P273 WeakPolarHBondContact O-CD 3.39Å; M268-P273 WeakPolarHBondContact O-CG 3.48Å
269	K	69.3	Low	62.3	Low	134 Å²	134	73 Å²	73	58%	0.583	36%	0.36	S	S	*	.	I	π-helix	trans	-81.7	-31.2	-172.2	-71.9	-176.6	177.7	178.6	0	113.2	Q265 P273	Q265-K269 VanDerWaalsContact O-CB 3.28Å; Q265-K269 WeakPolarHBondContact O-CB 3.42Å; Q265-K269 WeakPolarHBondContact O-CG 3.36Å; Q265-K269 PolarHBondContact O-N 2.89Å; K269-P273 VanDerWaalsContact O-CG 3.31Å; K269-P273 WeakPolarHBondContact O-CG 3.37Å
270	Y	64.8	Low	59.7	Low	87 Å²	87	76.3 Å²	76.3	34%	0.341	38%	0.381	S	S	.	.	I	π-helix	trans	-118.7	-31.4	-170	-57.7	-84.6	0	0	0	112.3	K230 I236 L266	K230-Y270 HydrophobicContact CB-CE1 4.23Å; K230-Y270 HydrophobicContact CG-CD2 4.32Å; K230-Y270 HydrophobicContact CG-CE1 4.22Å; K230-Y270 HydrophobicContact CG-CE2 3.78Å; I236-Y270 VanDerWaalsContact CD1-C 3.45Å; I236-Y270 WeakPolarHBondContact CD1-O 3.41Å; I236-Y270 WeakPolarHBondContact CG1-O 2.97Å; L266-Y270 HydrophobicContact CD1-CD2 4Å; L266-Y270 WeakPolarHBondContact O-CB 3.34Å; L266-Y270 PolarHBondContact O-N 2.87Å
271	I	58.2	Low	57.4	Low	13 Å²	13	87.6 Å²	87.6	7%	0.067	43%	0.433	C	S	.	.	I	π-helix	trans	-100.8	-33.4	-167.8	-55	177.3	0	0	0	112.6	I236 R241 Y244 L266 L267	I236-I271 HydrophobicContact CD1-CB 4.38Å; I236-I271 HydrophobicContact CD1-CG1 3.56Å; I236-I271 HydrophobicContact CG2-CG1 4.2Å; I236-I271 HydrophobicContact CG2-CG2 4.32Å; R241-I271 HydrophobicContact CB-CG2 3.19Å; R241-I271 HydrophobicContact CG-CG2 3.37Å; Y244-I271 HydrophobicContact CD2-CD1 4.17Å; L266-I271 HydrophobicContact CD2-CD1 4.35Å; L266-I271 HydrophobicContact CG-CD1 4.25Å; L266-I271 PolarHBondContact O-N 3.25Å; L267-I271 HydrophobicContact CD2-CB 4.17Å; L267-I271 HydrophobicContact CD2-CD1 3.59Å; L267-I271 HydrophobicContact CD2-CG1 4.39Å; L267-I271 HydrophobicContact CD2-CG2 4.09Å; L267-I271 HydrophobicContact CG-CD1 4.16Å; L267-I271 CarbonylContact O-C 3.47Å; L267-I271 WeakPolarHBondContact O-CA 3.41Å; L267-I271 VanDerWaalsContact O-CB 3.31Å; L267-I271 WeakPolarHBondContact O-CB 3.35Å; L267-I271 PolarHBondContact O-N 3.48Å; L267-I271 VanDerWaalsContact O-N 3.12Å
272	L	58.1	Low	56.3	Low	19 Å²	19	87 Å²	87	10%	0.099	43%	0.431	C	S	.	.	S	Bend	trans	-91.5	-21.6	-178.4	-70.6	178.2	0	0	0	117.7	I4 I5 L267 M268 G274 M275	I4-L272 HydrophobicContact CG2-CD2 4.4Å; I5-L272 HydrophobicContact CD1-CD1 4.17Å; I5-L272 HydrophobicContact CG1-CD1 3.74Å; L267-L272 WeakPolarHBondContact O-CB 3.42Å; L267-L272 WeakPolarHBondContact O-CG 3.48Å; L267-L272 PolarHBondContact O-N 2.88Å; M268-L272 HydrophobicContact SD-CD1 3.98Å; L272-G274 PolarHBondContact O-N 2.59Å; L272-M275 HydrophobicContact CD2-SD 4.18Å; L272-M275 PolarHBondContact O-N 2.87Å
273	P	52.5	Low	54.9	Low	95 Å²	95	87.2 Å²	87.2	62%	0.617	43%	0.433	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.8	9.5	-174.3	-22.2	32.3	0	0	0	117.6	M268 K269	M268-P273 WeakPolarHBondContact O-CD 3.39Å; M268-P273 WeakPolarHBondContact O-CG 3.48Å; K269-P273 VanDerWaalsContact O-CG 3.31Å; K269-P273 WeakPolarHBondContact O-CG 3.37Å
274	G	48.2	Very low	53.5	Low	37 Å²	37	91.8 Å²	91.8	38%	0.381	46%	0.456	S	S	.	.	T	Hydrogen-bonded Turn	trans	-106.1	7.4	175.8	0	0	0	0	0	114.8	L272 E276	L272-G274 PolarHBondContact O-N 2.59Å; G274-E276 PolarHBondContact O-N 3.03Å
275	M	44.5	Very low	52.3	Low	75 Å²	75	95.6 Å²	95.6	37%	0.369	48%	0.475	S	S	.	.			trans	-77.7	78.9	170.9	-64.6	-173.1	87	0	0	109.3	I4 L272 F277	I4-M275 HydrophobicContact CG2-SD 3.98Å; L272-M275 HydrophobicContact CD2-SD 4.18Å; L272-M275 PolarHBondContact O-N 2.87Å; M275-F277 VanDerWaalsContact C-N 3.28Å; M275-F277 HydrophobicContact CB-CD2 4.31Å; M275-F277 HydrophobicContact CB-CE2 4.21Å; M275-F277 HydrophobicContact CE-CZ 4.31Å; M275-F277 PolarHBondContact O-N 3.09Å; M275-F277 VanDerWaalsContact O-N 3.1Å
276	E	38.8	Very low	50.5	Low	160 Å²	160	95.2 Å²	95.2	75%	0.748	47%	0.474	S	S	*	.			trans	-60.6	105	143.5	-78.1	167.9	-171.4	0	0	105	G274 N278	G274-E276 PolarHBondContact O-N 3.03Å; E276-N278 VanDerWaalsContact C-N 3.32Å; E276-N278 PolarHBondContact O-N 3.44Å
277	F	40.1	Very low	48.7	Very low	131 Å²	131	101.3 Å²	101.3	58%	0.575	51%	0.505	S	S	*	.			trans	-64.5	102.3	165.8	-79	-96.3	0	0	0	105.7	I4 M275 E279	I4-F277 HydrophobicContact CD1-CE2 4.19Å; I4-F277 HydrophobicContact CD1-CZ 3.85Å; M275-F277 VanDerWaalsContact C-N 3.28Å; M275-F277 HydrophobicContact CB-CD2 4.31Å; M275-F277 HydrophobicContact CB-CE2 4.21Å; M275-F277 HydrophobicContact CE-CZ 4.31Å; M275-F277 PolarHBondContact O-N 3.09Å; M275-F277 VanDerWaalsContact O-N 3.1Å; F277-E279 HydrophobicContact CB-CG 4.16Å; F277-E279 PolarHBondContact O-N 2.85Å
278	N	32.2	Very low	47.1	Very low	140 Å²	140	108.5 Å²	108.5	75%	0.749	54%	0.541	S	S	*	.			trans	-64.1	89.5	153.1	-77.6	-10.5	0	0	0	105.6	E276 N280	E276-N278 VanDerWaalsContact C-N 3.32Å; E276-N278 PolarHBondContact O-N 3.44Å; N278-N280 PolarHBondContact O-N 3.36Å
279	E	27.4	Very low	45.3	Very low	171 Å²	171	113.1 Å²	113.1	80%	0.799	56%	0.564	S	S	*	*			trans	-68.6	11.6	170.2	-85.7	-175.2	164.6	0	0	112.7	F277	F277-E279 HydrophobicContact CB-CG 4.16Å; F277-E279 PolarHBondContact O-N 2.85Å
280	N	27.1	Very low	43.3	Very low	140 Å²	140	111.3 Å²	111.3	75%	0.749	56%	0.562	S	S	*	*			trans	-132.6	92.4	177.8	-67.3	-36.6	0	0	0	110.1	N278	N278-N280 PolarHBondContact O-N 3.36Å
281	Q	27.5	Very low	41.3	Very low	268 Å²	268	113.5 Å²	113.5	100%	1.252	58%	0.582	S	S	*	*			trans	175.7	0	142.6	-98	170.7	7.8	0	0	112.2

Retrieved 281 of 281 residues in 296.5 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).