A0A5K4FCG0_SCHMA Loading...

Sodium-dependent transporter

AlphaFold DB , UniProt , Accession A0A5K4FCG0, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 592 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	34.2	Very low	28.7	Very low	244 Å²	244	161.1 Å²	161.1	100%	1.202	88%	0.875	S	S	*	*				0	65	0	-78.4	-179.5	-178.2	0	0	109.8
2	T	29.5	Very low	28.4	Very low	150 Å²	150	162.8 Å²	162.8	92%	0.92	87%	0.868	S	S	*	*			trans	-110.1	92	-177.2	-22.2	0	0	0	0	106.9
3	R	31.3	Very low	28	Very low	248 Å²	248	162.5 Å²	162.5	94%	0.936	86%	0.858	S	S	*	*			trans	-102.2	110.2	171.6	-109.7	-176.1	179.7	-173.3	0.3	108.5
4	S	31.8	Very low	28.1	Very low	104 Å²	104	158.8 Å²	158.8	73%	0.727	85%	0.852	S	S	*	*			trans	-55.7	134.5	169.6	40.6	0	0	0	0	112	N6	S4-N6 PolarHBondContact O-N 3.47Å
5	L	29.8	Very low	27.7	Very low	164 Å²	164	156.8 Å²	156.8	86%	0.859	85%	0.848	S	S	*	*			trans	-84.1	105	166.4	-94	139.7	0	0	0	108.7
6	N	26.5	Very low	27.7	Very low	152 Å²	152	156.7 Å²	156.7	81%	0.813	85%	0.847	S	S	*	*			trans	-74.2	116.4	161.3	-82.8	-35.8	0	0	0	108.6	S4	S4-N6 PolarHBondContact O-N 3.47Å
7	I	31.8	Very low	27.5	Very low	147 Å²	147	155.3 Å²	155.3	75%	0.754	85%	0.845	S	S	*	*			trans	-119.8	110.1	157.8	-61.3	-179.5	0	0	0	108.6
8	M	25.6	Very low	27.2	Very low	176 Å²	176	153.7 Å²	153.7	87%	0.867	85%	0.846	S	S	*	*			trans	-9	126.6	167.2	-74.7	175.9	-86.6	0	0	120.3
9	K	22.3	Very low	26.9	Very low	205 Å²	205	153.3 Å²	153.3	89%	0.891	84%	0.842	S	S	*	*			trans	-52.9	142.4	143.6	-66.9	168.7	168.8	177.1	0	112.1
10	A	25.8	Very low	26.9	Very low	108 Å²	108	153.2 Å²	153.2	89%	0.893	84%	0.841	S	S	*	*				174.8	133.7	129.2	0	0	0	0	0	111.8
11	G	27.4	Very low	26.8	Very low	74 Å²	74	151.4 Å²	151.4	76%	0.763	84%	0.835	S	S	*	*			trans	141.1	63.9	173	0	0	0	0	0	111.6
12	K	24.4	Very low	26.4	Very low	181 Å²	181	146.3 Å²	146.3	79%	0.787	81%	0.812	S	S	*	*				78	124.5	93.4	-95.5	-170.2	162.9	-143.6	0	115
13	E	24.1	Very low	26.3	Very low	159 Å²	159	148.2 Å²	148.2	74%	0.743	81%	0.808	S	S	*	*			trans	79.2	97.7	145.4	-68.3	165.5	-155.6	0	0	118.9
14	S	29	Very low	25.9	Very low	111 Å²	111	145.9 Å²	145.9	78%	0.776	81%	0.805	S	S	*	*				-168.9	98.2	128	171.9	0	0	0	0	108.8	N16	S14-N16 PolarHBondContact O-N 3.22Å
15	T	22.5	Very low	25.6	Very low	129 Å²	129	148.4 Å²	148.4	79%	0.791	81%	0.81	S	S	*	*			trans	-56.7	118.7	165.1	41.2	0	0	0	0	110.5
16	N	28	Very low	25.3	Very low	155 Å²	155	147.3 Å²	147.3	83%	0.829	80%	0.804	S	S	*	*			trans	-141.4	98.8	148.6	-100.1	-18	0	0	0	108.1	S14 C18	S14-N16 PolarHBondContact O-N 3.22Å; N16-C18 PolarHBondContact O-N 3.05Å
17	T	23.1	Very low	25.2	Very low	133 Å²	133	147.3 Å²	147.3	82%	0.816	80%	0.804	S	S	*	*			trans	-63.1	112.4	168.4	40.3	0	0	0	0	109.4
18	C	22.8	Very low	25	Very low	127 Å²	127	149 Å²	149	86%	0.858	81%	0.809	S	S	*	*			trans	-132.9	86.6	154.9	-129.6	0	0	0	0	107.5	N16 N20	N16-C18 PolarHBondContact O-N 3.05Å; C18-N20 PolarHBondContact O-N 3.41Å
19	N	22	Very low	25.1	Very low	146 Å²	146	148.8 Å²	148.8	78%	0.781	81%	0.809	S	S	*	*			trans	-63.3	123.5	156.8	-78.1	-17.8	0	0	0	107.4
20	N	26.5	Very low	25.2	Very low	151 Å²	151	144 Å²	144	81%	0.807	80%	0.802	S	S	*	*				-174.9	103.2	126.2	-95	-11.7	0	0	0	109.5	C18	C18-N20 PolarHBondContact O-N 3.41Å
21	T	23.7	Very low	25.2	Very low	116 Å²	116	144 Å²	144	71%	0.712	80%	0.796	S	S	*	*			trans	-41.7	125	135.8	36.3	0	0	0	0	109.9
22	D	27.4	Very low	25.3	Very low	137 Å²	137	150 Å²	150	73%	0.733	80%	0.804	S	S	*	*				178.6	133.8	104.6	-91.6	-40.1	0	0	0	113
23	K	27.5	Very low	25.2	Very low	190 Å²	190	148.4 Å²	148.4	83%	0.826	80%	0.804	S	S	*	*			trans	5.2	111.4	157.1	-68.7	170	178.7	173.2	0	117.4	N25	K23-N25 PolarHBondContact O-N 3.37Å; K23-N25 VanDerWaalsContact O-N 3.12Å
24	F	22.6	Very low	25.2	Very low	199 Å²	199	146.3 Å²	146.3	87%	0.873	80%	0.802	S	S	*	*			trans	-49.1	110.1	152.6	-97.9	-102.2	0	0	0	110.2
25	N	25.2	Very low	25.1	Very low	156 Å²	156	148.7 Å²	148.7	83%	0.834	81%	0.806	S	S	*	*			trans	-114.8	105	163.9	-144.7	-0.5	0	0	0	107.4	K23 N27	K23-N25 PolarHBondContact O-N 3.37Å; K23-N25 VanDerWaalsContact O-N 3.12Å; N25-N27 PolarHBondContact O-N 3.19Å
26	L	24.3	Very low	25.2	Very low	142 Å²	142	146 Å²	146	74%	0.743	80%	0.804	S	S	*	*			trans	-85.2	97.9	175.2	-79.9	154.4	0	0	0	107.2
27	N	24.3	Very low	25.2	Very low	152 Å²	152	144.6 Å²	144.6	81%	0.813	80%	0.801	S	S	*	*			trans	179.4	144.1	149.9	-86.6	-24.6	0	0	0	107.8	N25	N25-N27 PolarHBondContact O-N 3.19Å
28	E	27.3	Very low	25.3	Very low	181 Å²	181	143.6 Å²	143.6	85%	0.846	80%	0.799	S	S	*	*			trans	83.6	92.8	-175.6	-52.6	179.5	177.3	0	0	113.9
29	I	27.2	Very low	25.6	Very low	172 Å²	172	146.4 Å²	146.4	88%	0.882	80%	0.797	S	S	*	*				-161.3	93.7	115.4	-80.9	140	0	0	0	105.6
30	S	23.7	Very low	25.7	Very low	104 Å²	104	145.6 Å²	145.6	73%	0.727	80%	0.798	S	S	*	*			trans	-96.8	141.7	156.4	43.4	0	0	0	0	107.7
31	S	26.4	Very low	25.8	Very low	110 Å²	110	143.1 Å²	143.1	77%	0.769	79%	0.792	S	S	*	*			trans	65.1	97.1	171.1	65.3	0	0	0	0	117.6
32	Q	28.5	Very low	26.1	Very low	200 Å²	200	142.7 Å²	142.7	94%	0.935	79%	0.794	S	S	*	*				-153.1	138.8	129.4	-108.5	171.1	25.4	0	0	110.7
33	N	23.4	Very low	26.2	Very low	146 Å²	146	141.2 Å²	141.2	78%	0.781	80%	0.795	S	S	*	*			trans	-76.7	161	-167.4	-90.7	-27.1	0	0	0	113.6
34	T	23.8	Very low	26.2	Very low	115 Å²	115	136.6 Å²	136.6	71%	0.706	79%	0.787	S	S	*	*			trans	55.1	104	142	56.2	0	0	0	0	118.2
35	D	27.5	Very low	26.6	Very low	162 Å²	162	134.2 Å²	134.2	87%	0.866	78%	0.781	S	S	*	*				179.8	145.9	104.8	-88.3	-23.9	0	0	0	110.9
36	G	25.2	Very low	26.5	Very low	73 Å²	73	135.6 Å²	135.6	75%	0.753	78%	0.78	S	S	*	*			trans	-67.5	136.4	-162.4	0	0	0	0	0	115.6
37	T	27.6	Very low	26.6	Very low	124 Å²	124	133.9 Å²	133.9	76%	0.761	77%	0.771	S	S	*	*			trans	-154.7	104.6	138	39.6	0	0	0	0	108	F39	T37-F39 PolarHBondContact O-N 3.2Å; T37-F39 VanDerWaalsContact O-N 3.14Å
38	S	25	Very low	26.7	Very low	112 Å²	112	135 Å²	135	78%	0.783	77%	0.771	S	S	*	*			trans	-72.3	94.9	171.2	52.9	0	0	0	0	110
39	F	27.8	Very low	26.7	Very low	186 Å²	186	131.1 Å²	131.1	82%	0.816	76%	0.76	S	S	*	*			trans	-110.8	69.4	160.1	-87.3	-81.6	0	0	0	109.4	T37	T37-F39 PolarHBondContact O-N 3.2Å; T37-F39 VanDerWaalsContact O-N 3.14Å
40	T	25.4	Very low	26.9	Very low	130 Å²	130	126.2 Å²	126.2	80%	0.798	74%	0.738	S	S	*	*			trans	-95.8	76.8	160.8	42.3	0	0	0	0	108.7
41	S	28.8	Very low	27.5	Very low	98 Å²	98	125.3 Å²	125.3	69%	0.685	74%	0.737	S	S	*	*			trans	-107.2	79	155	67.6	0	0	0	0	107.6	S43	S41-S43 VanDerWaalsContact C-N 3.28Å; S41-S43 PolarHBondContact O-N 3.45Å
42	S	29.8	Very low	28.5	Very low	107 Å²	107	126.5 Å²	126.5	75%	0.748	73%	0.73	S	S	*	*			trans	-53.7	102.1	156.1	-39.1	0	0	0	0	105.7	S44	S42-S44 PolarHBondContact O-N 3.18Å
43	S	30	Very low	30.1	Very low	106 Å²	106	118.1 Å²	118.1	74%	0.741	69%	0.691	S	S	*	*			trans	-64.6	85	168.2	41.5	0	0	0	0	106.5	S41 I45	S41-S43 VanDerWaalsContact C-N 3.28Å; S41-S43 PolarHBondContact O-N 3.45Å; S43-I45 VanDerWaalsContact C-N 3.29Å; S43-I45 PolarHBondContact O-N 3.28Å
44	S	27.2	Very low	32.4	Very low	94 Å²	94	113.1 Å²	113.1	66%	0.657	67%	0.667	S	S	*	*			trans	-55.2	102	164.5	54.1	0	0	0	0	105.8	S42 K46	S42-S44 PolarHBondContact O-N 3.18Å; S44-K46 PolarHBondContact O-N 3.06Å
45	I	29.7	Very low	35.3	Very low	148 Å²	148	109.7 Å²	109.7	76%	0.759	64%	0.644	S	S	*	*			trans	-57.7	99.2	167.7	-66	170.7	0	0	0	104.3	S43 L47	S43-I45 VanDerWaalsContact C-N 3.29Å; S43-I45 PolarHBondContact O-N 3.28Å; I45-L47 PolarHBondContact O-N 2.95Å
46	K	23.6	Very low	38.1	Very low	186 Å²	186	103 Å²	103	81%	0.809	61%	0.607	S	S	*	*			trans	-68.3	92.8	170.2	-83.6	-175.4	174.8	-179.6	0	106.1	S44 Q48	S44-K46 PolarHBondContact O-N 3.06Å; K46-Q48 PolarHBondContact O-N 3.25Å; K46-Q48 VanDerWaalsContact O-N 3.1Å
47	L	27.7	Very low	40.9	Very low	106 Å²	106	105 Å²	105	56%	0.555	60%	0.596	S	S	*	*			trans	-57.2	113.7	166.2	-95	154.5	0	0	0	107.5	I45 V49 E564	I45-L47 PolarHBondContact O-N 2.95Å; L47-V49 PolarHBondContact O-N 2.7Å; L47-E564 HydrophobicContact CD1-CG 4.48Å; L47-E564 VanDerWaalsContact CD1-OE1 3.23Å; L47-E564 WeakPolarHBondContact CD1-OE1 3.26Å; L47-E564 VanDerWaalsContact CD1-OE2 3.28Å; L47-E564 WeakPolarHBondContact CD1-OE2 3.44Å
48	Q	24.5	Very low	43.8	Very low	174 Å²	174	101.4 Å²	101.4	81%	0.813	58%	0.577	S	S	*	*			trans	-67	101	171.8	-77.3	-174.7	-21	0	0	107.5	K46 T50	K46-Q48 PolarHBondContact O-N 3.25Å; K46-Q48 VanDerWaalsContact O-N 3.1Å; Q48-T50 VanDerWaalsContact C-N 3.27Å; Q48-T50 PolarHBondContact O-N 2.89Å; Q48-T50 PolarHBondContact O-OG1 3.44Å
49	V	28.9	Very low	46.8	Very low	100 Å²	100	99.3 Å²	99.3	61%	0.606	57%	0.566	S	S	*	*			trans	-58.3	98.6	163.8	-180	0	0	0	0	106.3	L47	L47-V49 PolarHBondContact O-N 2.7Å
50	T	31.2	Very low	49.8	Very low	70 Å²	70	96.2 Å²	96.2	43%	0.429	56%	0.557	S	S	.	*			trans	-73.4	136.4	-179.8	-50.8	0	0	0	0	106.9	Q48 E52	Q48-T50 VanDerWaalsContact C-N 3.27Å; Q48-T50 PolarHBondContact O-N 2.89Å; Q48-T50 PolarHBondContact O-OG1 3.44Å; T50-E52 PolarHBondContact O-N 2.84Å
51	A	36.6	Very low	53	Low	85 Å²	85	90 Å²	90	70%	0.702	52%	0.519	S	S	*	.			trans	-32.3	118.8	-170.5	0	0	0	0	0	114.1	K53	A51-K53 PolarHBondContact O-N 3.23Å; A51-K53 VanDerWaalsContact O-N 3.13Å
52	E	45.6	Very low	56.1	Low	135 Å²	135	85.4 Å²	85.4	63%	0.631	49%	0.487	S	S	*	.			trans	-41.7	117.8	-179.2	-84.6	173.6	-171.3	0	0	111.7	T50 S54 M570	T50-E52 PolarHBondContact O-N 2.84Å; E52-S54 PolarHBondContact O-N 2.76Å; E52-M570 HydrophobicContact CG-CE 4.44Å; E52-M570 HydrophobicContact CG-SD 3.93Å; E52-M570 VanDerWaalsContact OE1-CG 3.23Å; E52-M570 WeakPolarHBondContact OE1-CG 3.44Å
53	K	62.2	Low	59.2	Low	24 Å²	24	82.1 Å²	82.1	10%	0.104	46%	0.46	C	S	.	.	P	Polyproline II helix	trans	-66.2	122.8	170.3	-166.8	177.1	-175.5	-172.8	0	107.5	A51 M55 R122 T289 F290	A51-K53 PolarHBondContact O-N 3.23Å; A51-K53 VanDerWaalsContact O-N 3.13Å; K53-M55 PolarHBondContact O-N 3.38Å; K53-M55 VanDerWaalsContact O-N 3.12Å; K53-R122 PolarHBondContact NZ-O 2.72Å; K53-T289 PolarHBondContact NZ-OG1 3.36Å; K53-F290 HydrophobicContact CD-CD1 4.34Å; K53-F290 HydrophobicContact CD-CE1 4.29Å; K53-F290 VanDerWaalsContact CE-CE1 3.47Å; K53-F290 HydrophobicContact CG-CD1 4.23Å; K53-F290 HydrophobicContact CG-CE1 4.15Å
54	S	72.3	Confident	62.4	Low	41 Å²	41	78.8 Å²	78.8	29%	0.287	43%	0.434	S	S	.	.	P	Polyproline II helix	trans	-53	119.2	178.1	58.9	0	0	0	0	110.9	E52 V214 F290	E52-S54 PolarHBondContact O-N 2.76Å; S54-V214 WeakPolarHBondContact O-CG1 3.35Å; S54-V214 WeakPolarHBondContact OG-CG1 3.45Å; S54-F290 WeakPolarHBondContact O-CD1 3.37Å
55	M	85.4	Confident	65.8	Low	43 Å²	43	74.3 Å²	74.3	21%	0.212	40%	0.403	C	S	.	.	P	Polyproline II helix	trans	-85.5	166.2	175.3	-62.1	-66.6	-82.6	0	0	111	K53 R122 F290 M291	K53-M55 PolarHBondContact O-N 3.38Å; K53-M55 VanDerWaalsContact O-N 3.12Å; M55-R122 PolarHBondContact SD-NH2 2.85Å; M55-F290 VanDerWaalsContact CE-O 3.22Å; M55-F290 WeakPolarHBondContact CE-O 3.44Å; M55-F290 VanDerWaalsContact SD-O 3.37Å; M55-M291 VanDerWaalsContact CE-C 3.47Å
56	F	86.1	Confident	69	Low	22 Å²	22	67.2 Å²	67.2	10%	0.096	37%	0.366	C	S	.	.	P	Polyproline II helix	trans	-57.4	141.4	159.2	-71.6	-70	0	0	0	109.5	S58 V214 E218 Y287 F290 M291	F56-S58 VanDerWaalsContact C-N 3.27Å; F56-V214 HydrophobicContact CD1-CG2 3.7Å; F56-V214 HydrophobicContact CE1-CG2 3.34Å; F56-V214 HydrophobicContact CE2-CG2 4.33Å; F56-V214 HydrophobicContact CG-CG2 4.33Å; F56-V214 HydrophobicContact CZ-CG2 3.7Å; F56-E218 WeakPolarHBondContact CA-OE2 3.14Å; F56-E218 HydrophobicContact CD1-CB 4.25Å; F56-Y287 WeakPolarHBondContact CE2-O 3.39Å; F56-Y287 HydrophobicContact CZ-CD1 4.34Å; F56-Y287 HydrophobicContact CZ-CG 4.17Å; F56-F290 HydrophobicContact CD2-CB 3.79Å; F56-F290 HydrophobicContact CE2-CB 3.85Å; F56-F290 HydrophobicContact CE2-CD2 4.45Å; F56-F290 PolarHBondContact N-O 3.21Å; F56-M291 HydrophobicContact CD2-CG 4.36Å; F56-M291 HydrophobicContact CE2-CE 4.4Å; F56-M291 HydrophobicContact CE2-CG 4.47Å
57	Q	84.2	Confident	72.5	Confident	113 Å²	113	58.8 Å²	58.8	53%	0.528	33%	0.331	S	S	.	.	S	Bend	trans	-70.7	-27.8	179.9	-53.1	-169.8	-58.1	0	0	111.7	K215 E218	Q57-K215 HydrophobicContact CG-CG 4.33Å; Q57-E218 WeakPolarHBondContact CB-OE2 3Å; Q57-E218 WeakPolarHBondContact CG-OE2 3.45Å; Q57-E218 PolarHBondContact N-OE1 3.18Å; Q57-E218 PolarHBondContact N-OE2 2.86Å
58	S	87.6	Confident	75.8	Confident	50 Å²	50	53.8 Å²	53.8	35%	0.35	30%	0.304	S	S	.	.			trans	-147.2	152.8	179.8	66.4	0	0	0	0	112	F56 I60 G61 G62 E218	F56-S58 VanDerWaalsContact C-N 3.27Å; S58-I60 VanDerWaalsContact C-N 3.28Å; S58-I60 PolarHBondContact O-N 2.81Å; S58-G61 PolarHBondContact O-N 3.44Å; S58-G61 WeakPolarHBondContact OG-CA 3.4Å; S58-G61 PolarHBondContact OG-N 3.12Å; S58-G62 PolarHBondContact O-N 3.01Å; S58-E218 PolarHBondContact N-OE1 3.12Å; S58-E218 VanDerWaalsContact N-OE1 3.11Å; S58-E218 PolarHBondContact OG-OE1 3.35Å
59	A	87.6	Confident	79.2	Confident	68 Å²	68	45.5 Å²	45.5	56%	0.562	27%	0.265	S	S	*	.	H	α-helix	trans	-59.8	-40.6	173.5	0	0	0	0	0	111.7	G62 I63	A59-G62 PolarHBondContact O-N 3.36Å; A59-I63 WeakPolarHBondContact O-CG1 3.35Å; A59-I63 PolarHBondContact O-N 3.38Å
60	I	92.1	Very high	82.4	Confident	120 Å²	120	40.8 Å²	40.8	62%	0.615	24%	0.237	S	C	*	.	H	α-helix	trans	-63.1	-45.7	176.9	-66.6	171.5	0	0	0	110.6	S58 G62 I63 I64	S58-I60 VanDerWaalsContact C-N 3.28Å; S58-I60 PolarHBondContact O-N 2.81Å; I60-G62 VanDerWaalsContact C-N 3.3Å; I60-G62 PolarHBondContact O-N 2.89Å; I60-I63 PolarHBondContact O-N 3.3Å; I60-I64 HydrophobicContact CG2-CD1 3.61Å; I60-I64 HydrophobicContact CG2-CG1 4.16Å; I60-I64 WeakPolarHBondContact O-CB 3.27Å; I60-I64 VanDerWaalsContact O-CG1 3.31Å; I60-I64 WeakPolarHBondContact O-CG1 3.32Å; I60-I64 PolarHBondContact O-N 3.02Å
61	G	92.9	Very high	85.4	Confident	0 Å²	0	37.5 Å²	37.5	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-63.8	-34.4	177.7	0	0	0	0	0	113.2	S58 S65 E218	S58-G61 PolarHBondContact O-N 3.44Å; S58-G61 WeakPolarHBondContact OG-CA 3.4Å; S58-G61 PolarHBondContact OG-N 3.12Å; G61-S65 VanDerWaalsContact O-CB 3.29Å; G61-S65 WeakPolarHBondContact O-CB 3.29Å; G61-S65 PolarHBondContact O-N 3.45Å; G61-S65 PolarHBondContact O-OG 2.91Å; G61-E218 WeakPolarHBondContact CA-OE1 3.42Å
62	G	93.2	Very high	88.1	Confident	2 Å²	2	33.8 Å²	33.8	2%	0.021	19%	0.187	C	C	.	.	H	α-helix	trans	-61.7	-50	169.4	0	0	0	0	0	112.7	S58 A59 I60 S65 C66	S58-G62 PolarHBondContact O-N 3.01Å; A59-G62 PolarHBondContact O-N 3.36Å; I60-G62 VanDerWaalsContact C-N 3.3Å; I60-G62 PolarHBondContact O-N 2.89Å; G62-S65 PolarHBondContact O-N 2.64Å; G62-C66 PolarHBondContact O-N 3.18Å; G62-C66 PolarHBondContact O-SG 2.91Å
63	I	95.7	Very high	90.3	Very high	37 Å²	37	27.4 Å²	27.4	19%	0.19	16%	0.158	C	C	.	.	H	α-helix	trans	-62	-47.8	178	-65.3	165.3	0	0	0	111.1	A59 I60 S65 C66 V67 Y300 I304	A59-I63 WeakPolarHBondContact O-CG1 3.35Å; A59-I63 PolarHBondContact O-N 3.38Å; I60-I63 PolarHBondContact O-N 3.3Å; I63-S65 VanDerWaalsContact C-N 3.26Å; I63-S65 PolarHBondContact O-N 3.41Å; I63-C66 WeakPolarHBondContact O-CB 3.1Å; I63-C66 PolarHBondContact O-N 3.24Å; I63-C66 VanDerWaalsContact O-N 3.15Å; I63-V67 WeakPolarHBondContact O-CG2 3.33Å; I63-V67 PolarHBondContact O-N 3.25Å; I63-Y300 HydrophobicContact CD1-CD1 4.33Å; I63-Y300 HydrophobicContact CD1-CE1 3.54Å; I63-Y300 HydrophobicContact CG1-CD1 4.28Å; I63-Y300 HydrophobicContact CG1-CE1 3.82Å; I63-Y300 HydrophobicContact CG1-CE2 4.11Å; I63-I304 HydrophobicContact CG2-CD1 4.37Å; I63-I304 HydrophobicContact CG2-CG1 4.46Å
64	I	96.9	Very high	91.6	Very high	36 Å²	36	26.3 Å²	26.3	19%	0.185	15%	0.153	C	C	.	.	H	α-helix	trans	-59.7	-39.7	178.2	-71.6	176.7	0	0	0	110.4	I60 V67 G68 N221 I222 V225	I60-I64 HydrophobicContact CG2-CD1 3.61Å; I60-I64 HydrophobicContact CG2-CG1 4.16Å; I60-I64 WeakPolarHBondContact O-CB 3.27Å; I60-I64 VanDerWaalsContact O-CG1 3.31Å; I60-I64 WeakPolarHBondContact O-CG1 3.32Å; I60-I64 PolarHBondContact O-N 3.02Å; I64-V67 PolarHBondContact O-N 3.31Å; I64-G68 PolarHBondContact O-N 3.46Å; I64-N221 HydrophobicContact CG2-CB 4.17Å; I64-N221 VanDerWaalsContact CG2-O 3.25Å; I64-N221 WeakPolarHBondContact CG2-O 3.43Å; I64-I222 HydrophobicContact CD1-CG1 4.49Å; I64-V225 HydrophobicContact CG2-CB 3.77Å; I64-V225 HydrophobicContact CG2-CG1 4.15Å; I64-V225 HydrophobicContact CG2-CG2 4.08Å
65	S	97.2	Very high	92.6	Very high	0 Å²	0	24.5 Å²	24.5	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-64.9	-42.1	176	-62.2	0	0	0	0	112.1	G61 G62 I63 V67 G68 G69 N221 Y287	G61-S65 VanDerWaalsContact O-CB 3.29Å; G61-S65 WeakPolarHBondContact O-CB 3.29Å; G61-S65 PolarHBondContact O-N 3.45Å; G61-S65 PolarHBondContact O-OG 2.91Å; G62-S65 PolarHBondContact O-N 2.64Å; I63-S65 VanDerWaalsContact C-N 3.26Å; I63-S65 PolarHBondContact O-N 3.41Å; S65-V67 VanDerWaalsContact C-N 3.35Å; S65-V67 PolarHBondContact O-N 2.94Å; S65-G68 PolarHBondContact O-N 3.36Å; S65-G69 PolarHBondContact O-N 2.72Å; S65-N221 WeakPolarHBondContact CA-ND2 3.31Å; S65-N221 PolarHBondContact OG-ND2 3.16Å; S65-Y287 WeakPolarHBondContact O-CE2 3.46Å
66	C	97.4	Very high	93	Very high	0 Å²	0	22.6 Å²	22.6	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-63.7	-37.8	173.4	-70.2	0	0	0	0	112.6	G62 I63 G69 A70 Y115 M284 I304	G62-C66 PolarHBondContact O-N 3.18Å; G62-C66 PolarHBondContact O-SG 2.91Å; I63-C66 WeakPolarHBondContact O-CB 3.1Å; I63-C66 PolarHBondContact O-N 3.24Å; I63-C66 VanDerWaalsContact O-N 3.15Å; C66-G69 PolarHBondContact O-N 3.48Å; C66-A70 PolarHBondContact O-N 3.46Å; C66-Y115 WeakPolarHBondContact CB-OH 3.2Å; C66-M284 HydrophobicContact CB-CE 4.43Å; C66-M284 HydrophobicContact CB-SD 3.94Å; C66-M284 WeakPolarHBondContact O-CE 3.44Å; C66-I304 HydrophobicContact CB-CD1 3.58Å
67	V	97.4	Very high	93	Very high	9 Å²	9	22.8 Å²	22.8	6%	0.055	13%	0.131	C	C	.	.	H	α-helix	trans	-62.3	-44.3	171.5	174.3	0	0	0	0	110.5	I63 I64 S65 G69 A70 V71 V225 I304 I307	I63-V67 WeakPolarHBondContact O-CG2 3.33Å; I63-V67 PolarHBondContact O-N 3.25Å; I64-V67 PolarHBondContact O-N 3.31Å; S65-V67 VanDerWaalsContact C-N 3.35Å; S65-V67 PolarHBondContact O-N 2.94Å; V67-G69 PolarHBondContact O-N 2.86Å; V67-A70 PolarHBondContact O-N 3Å; V67-A70 VanDerWaalsContact O-N 3.16Å; V67-V71 HydrophobicContact CG1-CG2 3.96Å; V67-V71 WeakPolarHBondContact O-CB 3.43Å; V67-V71 PolarHBondContact O-N 3.09Å; V67-V225 HydrophobicContact CB-CG1 4.19Å; V67-V225 HydrophobicContact CG1-CG1 3.68Å; V67-I304 HydrophobicContact CG2-CG1 4.19Å; V67-I304 HydrophobicContact CG2-CG2 4.18Å; V67-I307 HydrophobicContact CG1-CG2 4.26Å
68	G	96.5	Very high	93.2	Very high	0 Å²	0	20 Å²	20	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-64.1	-26.9	176.5	0	0	0	0	0	114.1	I64 S65 V225 S386 S387	I64-G68 PolarHBondContact O-N 3.46Å; S65-G68 PolarHBondContact O-N 3.36Å; G68-V225 VanDerWaalsContact CA-CG2 3.46Å; G68-S386 CarbonylContact O-C 3.5Å; G68-S386 WeakPolarHBondContact O-CB 3.32Å; G68-S386 PolarHBondContact O-OG 3.46Å; G68-S387 PolarHBondContact O-N 3.01Å
69	G	95.6	Very high	93.5	Very high	0 Å²	0	17.6 Å²	17.6	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-80.8	-26.5	172.8	0	0	0	0	0	114.5	S65 C66 V67 S278 S390	S65-G69 PolarHBondContact O-N 2.72Å; C66-G69 PolarHBondContact O-N 3.48Å; V67-G69 PolarHBondContact O-N 2.86Å; G69-S278 PolarHBondContact O-OG 3.42Å; G69-S390 WeakPolarHBondContact CA-OG 3.33Å
70	A	95.7	Very high	93.7	Very high	2 Å²	2	14.4 Å²	14.4	2%	0.017	7%	0.072	C	C	.	.	H	α-helix	trans	-84	-50.4	175.1	0	0	0	0	0	111.6	C66 V67 G72 M284 I304 N308	C66-A70 PolarHBondContact O-N 3.46Å; V67-A70 PolarHBondContact O-N 3Å; V67-A70 VanDerWaalsContact O-N 3.16Å; A70-G72 PolarHBondContact O-N 3.43Å; A70-G72 VanDerWaalsContact O-N 3.12Å; A70-M284 HydrophobicContact CB-CE 4.13Å; A70-I304 HydrophobicContact CB-CG2 4.1Å; A70-N308 VanDerWaalsContact C-OD1 3.23Å; A70-N308 HydrophobicContact CB-CB 4.27Å; A70-N308 PolarHBondContact O-OD1 3.02Å; A70-N308 VanDerWaalsContact O-OD1 3.14Å
71	V	95.8	Very high	93.7	Very high	0 Å²	0	9.9 Å²	9.9	0%	0	5%	0.048	C	C	.	.			trans	-76.3	102.9	-177.8	-179.7	0	0	0	0	109.7	V67 L228 N308 V311	V67-V71 HydrophobicContact CG1-CG2 3.96Å; V67-V71 WeakPolarHBondContact O-CB 3.43Å; V67-V71 PolarHBondContact O-N 3.09Å; V71-L228 HydrophobicContact CG1-CD1 3.81Å; V71-N308 WeakPolarHBondContact CA-OD1 3.48Å; V71-N308 HydrophobicContact CG2-CB 4.3Å; V71-N308 PolarHBondContact N-OD1 3.08Å; V71-V311 HydrophobicContact CG1-CB 4.39Å; V71-V311 HydrophobicContact CG1-CG1 3.81Å; V71-V311 HydrophobicContact CG1-CG2 4.41Å; V71-V311 HydrophobicContact CG2-CB 4.48Å; V71-V311 HydrophobicContact CG2-CG2 4.17Å
72	G	93	Very high	93.6	Very high	8 Å²	8	10.5 Å²	10.5	8%	0.082	5%	0.051	C	C	.	.			trans	-107.8	177.6	176.2	0	0	0	0	0	113	A70 G74 N75	A70-G72 PolarHBondContact O-N 3.43Å; A70-G72 VanDerWaalsContact O-N 3.12Å; G72-G74 PolarHBondContact O-N 3.26Å; G72-N75 PolarHBondContact N-OD1 2.97Å; G72-N75 PolarHBondContact O-N 3.14Å; G72-N75 PolarHBondContact O-OD1 3.42Å
73	T	92	Very high	93.6	Very high	1 Å²	1	10.4 Å²	10.4	1%	0.006	5%	0.05	C	C	.	.	H	α-helix	trans	-49.8	-41.7	168.4	53.5	0	0	0	0	111.4	N75 I76 W77 Y155 L380	T73-N75 PolarHBondContact O-N 2.99Å; T73-N75 VanDerWaalsContact O-N 3.11Å; T73-I76 PolarHBondContact O-N 3.45Å; T73-W77 PolarHBondContact O-N 2.61Å; T73-W77 VanDerWaalsContact O-N 3.07Å; T73-Y155 PolarHBondContact N-OH 3.2Å; T73-Y155 VanDerWaalsContact OG1-CE2 3.3Å; T73-Y155 WeakPolarHBondContact OG1-CE2 3.2Å; T73-Y155 PolarHBondContact OG1-OH 2.99Å; T73-L380 HydrophobicContact CG2-CB 4.45Å; T73-L380 HydrophobicContact CG2-CD2 4.24Å; T73-L380 WeakPolarHBondContact CG2-O 3.48Å
74	G	88.3	Confident	93.4	Very high	1 Å²	1	8.7 Å²	8.7	1%	0.01	4%	0.041	C	C	.	.	H	α-helix	trans	-50.5	-38.3	-178.1	0	0	0	0	0	114.8	G72 I76 R78 F79	G72-G74 PolarHBondContact O-N 3.26Å; G74-I76 PolarHBondContact O-N 3.14Å; G74-R78 WeakPolarHBondContact O-CA 3.29Å; G74-R78 VanDerWaalsContact O-CB 3.27Å; G74-R78 WeakPolarHBondContact O-CB 3.47Å; G74-R78 PolarHBondContact O-N 3.22Å; G74-F79 PolarHBondContact O-N 3.43Å
75	N	94.1	Very high	93.1	Very high	2 Å²	2	10.1 Å²	10.1	1%	0.011	5%	0.052	C	C	.	.	H	α-helix	trans	-61.2	-33.1	178.1	-59	51.3	0	0	0	112.4	G72 T73 F79 N308 V311 S312	G72-N75 PolarHBondContact N-OD1 2.97Å; G72-N75 PolarHBondContact O-N 3.14Å; G72-N75 PolarHBondContact O-OD1 3.42Å; T73-N75 PolarHBondContact O-N 2.99Å; T73-N75 VanDerWaalsContact O-N 3.11Å; N75-F79 WeakPolarHBondContact O-CB 3.49Å; N75-N308 VanDerWaalsContact ND2-CG 3.26Å; N75-N308 PolarHBondContact ND2-ND2 3.35Å; N75-N308 PolarHBondContact ND2-O 3.11Å; N75-N308 PolarHBondContact ND2-OD1 3.48Å; N75-V311 HydrophobicContact CB-CG1 4.22Å; N75-S312 WeakPolarHBondContact CB-OG 3.16Å; N75-S312 PolarHBondContact ND2-OG 2.93Å
76	I	93.5	Very high	92.8	Very high	4 Å²	4	11.6 Å²	11.6	2%	0.021	6%	0.06	C	C	.	.	H	α-helix	trans	-93.8	-46	-171.4	-56	164.3	0	0	0	110.8	T73 G74 P80 I232 A315 F376 C379 L380 A383	T73-I76 PolarHBondContact O-N 3.45Å; G74-I76 PolarHBondContact O-N 3.14Å; I76-P80 WeakPolarHBondContact O-CD 3.08Å; I76-P80 VanDerWaalsContact O-CG 3.3Å; I76-P80 WeakPolarHBondContact O-CG 3.24Å; I76-I232 HydrophobicContact CD1-CD1 3.84Å; I76-I232 HydrophobicContact CG1-CD1 3.76Å; I76-A315 HydrophobicContact CB-CB 4.48Å; I76-A315 HydrophobicContact CG2-CB 4.44Å; I76-F376 HydrophobicContact CG2-CD2 4.45Å; I76-F376 HydrophobicContact CG2-CE2 3.66Å; I76-F376 HydrophobicContact CG2-CZ 4.08Å; I76-C379 VanDerWaalsContact CD1-SG 3.54Å; I76-L380 HydrophobicContact CB-CD2 3.67Å; I76-L380 HydrophobicContact CD1-CD2 4.14Å; I76-L380 HydrophobicContact CG2-CD2 3.83Å; I76-L380 HydrophobicContact CG2-CG 4.26Å; I76-A383 HydrophobicContact CD1-CB 3.92Å
77	W	86	Confident	92.4	Very high	26 Å²	26	11.7 Å²	11.7	10%	0.098	6%	0.061	C	C	.	.	H	α-helix	trans	-101.5	-39.7	-173	81.1	-89.5	0	0	0	113.6	T73 V158 T351 T354 F355 L380	T73-W77 PolarHBondContact O-N 2.61Å; T73-W77 VanDerWaalsContact O-N 3.07Å; W77-V158 HydrophobicContact CH2-CG1 4.47Å; W77-V158 HydrophobicContact CZ2-CG1 3.71Å; W77-T351 HydrophobicContact CH2-CG2 4.32Å; W77-T351 HydrophobicContact CZ3-CG2 4.07Å; W77-T354 HydrophobicContact CB-CG2 3.71Å; W77-T354 WeakPolarHBondContact CB-OG1 3.17Å; W77-F355 HydrophobicContact CE3-CE2 4.11Å; W77-F355 HydrophobicContact CZ3-CE2 4.26Å; W77-L380 HydrophobicContact CB-CD2 4Å; W77-L380 HydrophobicContact CG-CD2 4.36Å
78	R	88.3	Confident	91.8	Very high	53 Å²	53	14.8 Å²	14.8	20%	0.2	8%	0.077	C	C	.	.	H	α-helix	trans	-80.7	-45.3	-175.8	-172.2	-176.7	-168.6	-102.6	13.3	111.4	G74 R81 V82	G74-R78 WeakPolarHBondContact O-CA 3.29Å; G74-R78 VanDerWaalsContact O-CB 3.27Å; G74-R78 WeakPolarHBondContact O-CB 3.47Å; G74-R78 PolarHBondContact O-N 3.22Å; R78-R81 WeakPolarHBondContact O-CB 3.35Å; R78-R81 PolarHBondContact O-N 3.24Å; R78-V82 HydrophobicContact CG-CG2 4Å; R78-V82 WeakPolarHBondContact O-CG2 3.37Å; R78-V82 PolarHBondContact O-N 3.1Å
79	F	93.6	Very high	90.9	Very high	0 Å²	0	19.5 Å²	19.5	0%	0	11%	0.11	C	C	.	.	H	α-helix	trans	-57.4	-48.7	-174.9	179.2	-92.5	0	0	0	113.8	G74 N75 R81 V82 L83 F95 Y96 W99 Q272 D276 S312	G74-F79 PolarHBondContact O-N 3.43Å; N75-F79 WeakPolarHBondContact O-CB 3.49Å; F79-R81 VanDerWaalsContact C-N 3.26Å; F79-R81 PolarHBondContact O-N 3.28Å; F79-V82 PolarHBondContact O-N 3.34Å; F79-V82 VanDerWaalsContact O-N 3.17Å; F79-L83 HydrophobicContact CE1-CD2 4.42Å; F79-L83 WeakPolarHBondContact O-CB 3.39Å; F79-L83 PolarHBondContact O-N 3.44Å; F79-F95 AromaticContact CE2-CE1 3.89Å; F79-F95 HydrophobicContact CE2-CE1 3.89Å; F79-F95 HydrophobicContact CZ-CE1 4.27Å; F79-Y96 AromaticContact CE1-CE1 3.83Å; F79-Y96 HydrophobicContact CE1-CE1 3.83Å; F79-Y96 HydrophobicContact CZ-CD1 4.11Å; F79-Y96 AromaticContact CZ-CE1 3.76Å; F79-Y96 HydrophobicContact CZ-CE1 3.76Å; F79-W99 HydrophobicContact CD2-CZ2 4.22Å; F79-W99 AromaticContact CE2-CD2 3.82Å; F79-W99 HydrophobicContact CE2-CD2 3.82Å; F79-W99 AromaticContact CE2-CE2 3.41Å; F79-W99 VanDerWaalsContact CE2-CE2 3.41Å; F79-W99 HydrophobicContact CE2-CE3 4.31Å; F79-W99 HydrophobicContact CE2-CG 4.25Å; F79-W99 AromaticContact CE2-CH2 3.99Å; F79-W99 HydrophobicContact CE2-CH2 3.99Å; F79-W99 AromaticContact CE2-CZ2 3.51Å; F79-W99 HydrophobicContact CE2-CZ2 3.51Å; F79-W99 HydrophobicContact CE2-CZ3 4.39Å; F79-W99 AromaticContact CE2-NE1 3.63Å; F79-W99 HydrophobicContact CZ-CD2 4.15Å; F79-W99 HydrophobicContact CZ-CE3 4.17Å; F79-W99 AromaticContact CZ-CH2 3.88Å; F79-W99 HydrophobicContact CZ-CH2 3.88Å; F79-W99 AromaticContact CZ-CZ2 3.9Å; F79-W99 HydrophobicContact CZ-CZ2 3.9Å; F79-W99 HydrophobicContact CZ-CZ3 4.05Å; F79-Q272 HydrophobicContact CD2-CG 3.59Å; F79-Q272 HydrophobicContact CE2-CG 4.16Å; F79-D276 VanDerWaalsContact CD2-OD2 3.24Å; F79-D276 WeakPolarHBondContact CD2-OD2 3.43Å; F79-S312 VanDerWaalsContact CD1-O 3.27Å; F79-S312 WeakPolarHBondContact CD1-O 3.29Å; F79-S312 WeakPolarHBondContact CE1-O 3.44Å
80	P	93.3	Very high	90.1	Very high	1 Å²	1	21.3 Å²	21.3	1%	0.006	13%	0.128	C	C	.	.	H	α-helix	trans	-60	-36.6	179.2	-23.8	35.2	0	0	0	112.9	I76 A84 I319 F320	I76-P80 WeakPolarHBondContact O-CD 3.08Å; I76-P80 VanDerWaalsContact O-CG 3.3Å; I76-P80 WeakPolarHBondContact O-CG 3.24Å; P80-A84 WeakPolarHBondContact O-CB 3.46Å; P80-A84 PolarHBondContact O-N 3.32Å; P80-I319 HydrophobicContact CB-CB 4.09Å; P80-I319 HydrophobicContact CB-CG1 4.26Å; P80-I319 HydrophobicContact CB-CG2 4.08Å; P80-I319 HydrophobicContact CG-CB 4.36Å; P80-I319 HydrophobicContact CG-CG1 4.03Å; P80-F320 HydrophobicContact CB-CE2 4.41Å
81	R	90.5	Very high	89.9	Confident	26 Å²	26	21.2 Å²	21.2	10%	0.098	13%	0.128	C	C	.	.	H	α-helix	trans	-68.3	-47.5	175.4	-177	-165.7	63.6	81.4	-0.4	111.2	R78 F79 L83 A84 T85 S350 L353	R78-R81 WeakPolarHBondContact O-CB 3.35Å; R78-R81 PolarHBondContact O-N 3.24Å; F79-R81 VanDerWaalsContact C-N 3.26Å; F79-R81 PolarHBondContact O-N 3.28Å; R81-L83 VanDerWaalsContact C-N 3.28Å; R81-L83 PolarHBondContact O-N 3.12Å; R81-A84 CarbonylContact O-C 3.48Å; R81-A84 WeakPolarHBondContact O-CB 3.26Å; R81-A84 PolarHBondContact O-N 3.17Å; R81-A84 VanDerWaalsContact O-N 3.09Å; R81-T85 PolarHBondContact O-N 3.1Å; R81-T85 PolarHBondContact O-OG1 3.32Å; R81-T85 VanDerWaalsContact O-OG1 3.13Å; R81-S350 WeakPolarHBondContact CD-O 3.47Å; R81-S350 PolarHBondContact NE-O 3.26Å; R81-L353 HydrophobicContact CB-CD2 4.17Å
82	V	91.2	Very high	89.9	Confident	13 Å²	13	21.3 Å²	21.3	8%	0.079	13%	0.129	C	C	.	.	H	α-helix	trans	-61	-41.2	179.3	170.2	0	0	0	0	111	R78 F79 T85 N86 F95 Q272	R78-V82 HydrophobicContact CG-CG2 4Å; R78-V82 WeakPolarHBondContact O-CG2 3.37Å; R78-V82 PolarHBondContact O-N 3.1Å; F79-V82 PolarHBondContact O-N 3.34Å; F79-V82 VanDerWaalsContact O-N 3.17Å; V82-T85 PolarHBondContact O-N 3.15Å; V82-N86 WeakPolarHBondContact O-CB 3.5Å; V82-N86 PolarHBondContact O-N 2.7Å; V82-N86 PolarHBondContact O-ND2 3.06Å; V82-F95 HydrophobicContact CG1-CE2 4.04Å; V82-F95 HydrophobicContact CG1-CZ 3.85Å; V82-Q272 HydrophobicContact CG1-CB 4.17Å; V82-Q272 HydrophobicContact CG1-CG 4.19Å
83	L	94.1	Very high	90	Very high	0 Å²	0	22.8 Å²	22.8	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-58.8	-46.9	171.7	-180	69.2	0	0	0	111.6	F79 R81 N86 S87 A92 F95 Y96 L252 F320	F79-L83 HydrophobicContact CE1-CD2 4.42Å; F79-L83 WeakPolarHBondContact O-CB 3.39Å; F79-L83 PolarHBondContact O-N 3.44Å; R81-L83 VanDerWaalsContact C-N 3.28Å; R81-L83 PolarHBondContact O-N 3.12Å; L83-N86 CarbonylContact O-C 3.53Å; L83-N86 PolarHBondContact O-N 3.25Å; L83-S87 WeakPolarHBondContact O-CB 3.46Å; L83-S87 PolarHBondContact O-N 2.92Å; L83-S87 VanDerWaalsContact O-N 3.11Å; L83-A92 HydrophobicContact CD1-CB 3.9Å; L83-A92 HydrophobicContact CG-CB 4.07Å; L83-F95 HydrophobicContact CD1-CB 3.68Å; L83-F95 HydrophobicContact CD1-CD1 3.32Å; L83-F95 HydrophobicContact CD1-CE1 4.15Å; L83-F95 HydrophobicContact CD1-CG 3.68Å; L83-Y96 HydrophobicContact CD1-CD1 4.09Å; L83-Y96 HydrophobicContact CD1-CE1 3.94Å; L83-Y96 HydrophobicContact CD2-CE1 3.66Å; L83-Y96 HydrophobicContact CD2-CE2 4.39Å; L83-Y96 WeakPolarHBondContact CD2-OH 3.37Å; L83-Y96 HydrophobicContact CG-CE1 4.47Å; L83-L252 HydrophobicContact CD2-CD2 3.39Å; L83-L252 HydrophobicContact CG-CD2 4.36Å; L83-F320 HydrophobicContact CD2-CE2 4.18Å; L83-F320 HydrophobicContact CD2-CZ 4.39Å
84	A	91.9	Very high	90.2	Very high	0 Å²	0	22.8 Å²	22.8	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-61.4	-51.3	177.3	0	0	0	0	0	111.4	P80 R81 N86 S87 F320 I343 K344	P80-A84 WeakPolarHBondContact O-CB 3.46Å; P80-A84 PolarHBondContact O-N 3.32Å; R81-A84 CarbonylContact O-C 3.48Å; R81-A84 WeakPolarHBondContact O-CB 3.26Å; R81-A84 PolarHBondContact O-N 3.17Å; R81-A84 VanDerWaalsContact O-N 3.09Å; A84-N86 PolarHBondContact O-N 3.31Å; A84-S87 WeakPolarHBondContact O-CB 3.05Å; A84-S87 PolarHBondContact O-N 2.85Å; A84-S87 PolarHBondContact O-OG 3.38Å; A84-F320 HydrophobicContact CB-CE2 4.46Å; A84-F320 HydrophobicContact CB-CZ 3.81Å; A84-I343 HydrophobicContact CB-CB 3.91Å; A84-I343 HydrophobicContact CB-CG2 3.41Å; A84-I343 VanDerWaalsContact CB-CG2 3.41Å; A84-K344 HydrophobicContact CB-CG 4.11Å; A84-K344 WeakPolarHBondContact O-CE 3.16Å
85	T	89.8	Confident	90.6	Very high	66 Å²	66	22.8 Å²	22.8	41%	0.405	13%	0.134	S	C	.	.	H	α-helix	trans	-57	-35.6	179.9	-59.1	0	0	0	0	112.2	R81 V82	R81-T85 PolarHBondContact O-N 3.1Å; R81-T85 PolarHBondContact O-OG1 3.32Å; R81-T85 VanDerWaalsContact O-OG1 3.13Å; V82-T85 PolarHBondContact O-N 3.15Å
86	N	90.9	Very high	90.7	Very high	32 Å²	32	23.3 Å²	23.3	17%	0.171	14%	0.136	C	C	.	.	T	Hydrogen-bonded Turn	trans	-94.9	15	179.1	-68.3	-80.9	0	0	0	113.9	V82 L83 A84 F95 L265 A268	V82-N86 WeakPolarHBondContact O-CB 3.5Å; V82-N86 PolarHBondContact O-N 2.7Å; V82-N86 PolarHBondContact O-ND2 3.06Å; L83-N86 CarbonylContact O-C 3.53Å; L83-N86 PolarHBondContact O-N 3.25Å; A84-N86 PolarHBondContact O-N 3.31Å; N86-F95 HydrophobicContact CB-CD2 3.63Å; N86-F95 HydrophobicContact CB-CE2 4.01Å; N86-L265 HydrophobicContact CB-CD1 3.72Å; N86-A268 WeakPolarHBondContact ND2-CB 3.46Å; N86-A268 VanDerWaalsContact OD1-CB 3.29Å; N86-A268 WeakPolarHBondContact OD1-CB 3.38Å
87	S	89.8	Confident	90.8	Very high	2 Å²	2	25.7 Å²	25.7	1%	0.014	15%	0.148	C	C	.	.			trans	-102.9	152.6	172.1	72	0	0	0	0	111.5	L83 A84 F251 K344	L83-S87 WeakPolarHBondContact O-CB 3.46Å; L83-S87 PolarHBondContact O-N 2.92Å; L83-S87 VanDerWaalsContact O-N 3.11Å; A84-S87 WeakPolarHBondContact O-CB 3.05Å; A84-S87 PolarHBondContact O-N 2.85Å; A84-S87 PolarHBondContact O-OG 3.38Å; S87-F251 WeakPolarHBondContact OG-CZ 3.08Å; S87-K344 PolarHBondContact O-NZ 3.31Å
88	N	84.7	Confident	91.3	Very high	73 Å²	73	24.4 Å²	24.4	39%	0.39	14%	0.143	S	C	.	.	B	Isolated β-bridge	trans	-104.3	175.4	172.8	-80.4	-5.3	0	0	0	110.9	G90 G91 F251 T259	N88-G90 PolarHBondContact O-N 3.2Å; N88-G91 PolarHBondContact N-O 3.25Å; N88-G91 PolarHBondContact O-N 2.99Å; N88-G91 VanDerWaalsContact O-N 3.08Å; N88-F251 WeakPolarHBondContact O-CE2 3.43Å; N88-F251 WeakPolarHBondContact O-CZ 3.22Å; N88-T259 HydrophobicContact CB-CG2 4.3Å; N88-T259 WeakPolarHBondContact ND2-CG2 3.37Å
89	S	76.8	Confident	91.7	Very high	100 Å²	100	22.2 Å²	22.2	70%	0.699	14%	0.135	S	C	*	.	T	Hydrogen-bonded Turn	trans	-55	-23.8	176.8	53.8	0	0	0	0	113.6
90	G	78.8	Confident	91.9	Very high	37 Å²	37	25 Å²	25	38%	0.381	15%	0.152	S	C	.	.	T	Hydrogen-bonded Turn	trans	-77.5	-28.3	178.1	0	0	0	0	0	115.3	N88 T254	N88-G90 PolarHBondContact O-N 3.2Å; G90-T254 VanDerWaalsContact O-CB 3.28Å; G90-T254 WeakPolarHBondContact O-CB 3.23Å; G90-T254 WeakPolarHBondContact O-CG2 3.46Å
91	G	91.8	Very high	92.1	Very high	1 Å²	1	27.8 Å²	27.8	1%	0.01	17%	0.166	C	C	.	.	B	Isolated β-bridge	trans	145.3	-179.5	-176.7	0	0	0	0	0	114.5	N88 F251 T254	N88-G91 PolarHBondContact N-O 3.25Å; N88-G91 PolarHBondContact O-N 2.99Å; N88-G91 VanDerWaalsContact O-N 3.08Å; G91-F251 WeakPolarHBondContact CA-O 3.49Å; G91-T254 CarbonylContact C-O 3.43Å; G91-T254 WeakPolarHBondContact CA-O 3.31Å
92	A	94.7	Very high	92.3	Very high	2 Å²	2	26.8 Å²	26.8	2%	0.017	16%	0.163	C	C	.	.	S	Bend	trans	-119.7	-2.5	-171	0	0	0	0	0	115.5	L83 T94 F95 F251 L252 T254	L83-A92 HydrophobicContact CD1-CB 3.9Å; L83-A92 HydrophobicContact CG-CB 4.07Å; A92-T94 PolarHBondContact O-N 3.49Å; A92-T94 VanDerWaalsContact O-N 3.12Å; A92-F95 WeakPolarHBondContact O-CB 3.41Å; A92-F95 PolarHBondContact O-N 3.46Å; A92-F251 HydrophobicContact CB-CD1 4.44Å; A92-F251 HydrophobicContact CB-CE1 4Å; A92-F251 PolarHBondContact N-O 2.88Å; A92-L252 CarbonylContact C-O 3.56Å; A92-L252 HydrophobicContact CB-CD2 4.38Å; A92-T254 PolarHBondContact N-O 3.42Å
93	L	96.5	Very high	92.6	Very high	39 Å²	39	26.4 Å²	26.4	20%	0.204	16%	0.161	C	C	.	.	H	α-helix	trans	-59.9	-31.8	-171.7	177.8	61.7	0	0	0	113	F95 Y96 I97 L252 F253 T254 P255	L93-F95 VanDerWaalsContact C-N 3.26Å; L93-F95 PolarHBondContact O-N 3.48Å; L93-Y96 HydrophobicContact CD1-CD2 4.27Å; L93-Y96 WeakPolarHBondContact O-CB 3.06Å; L93-Y96 PolarHBondContact O-N 2.86Å; L93-Y96 VanDerWaalsContact O-N 3.12Å; L93-I97 HydrophobicContact CD1-CG1 4.38Å; L93-I97 HydrophobicContact CD2-CD1 4.5Å; L93-I97 HydrophobicContact CG-CD1 4.04Å; L93-I97 HydrophobicContact CG-CG1 4.33Å; L93-I97 WeakPolarHBondContact O-CG1 3.3Å; L93-I97 PolarHBondContact O-N 2.97Å; L93-L252 WeakPolarHBondContact CA-O 3.18Å; L93-L252 PolarHBondContact N-O 3.2Å; L93-L252 VanDerWaalsContact N-O 3.07Å; L93-F253 HydrophobicContact CD1-CD1 4.09Å; L93-F253 WeakPolarHBondContact CD2-O 3.16Å; L93-T254 WeakPolarHBondContact CB-O 3.33Å; L93-T254 PolarHBondContact N-O 3.13Å; L93-T254 VanDerWaalsContact N-O 3.15Å; L93-P255 HydrophobicContact CB-CB 4.45Å; L93-P255 HydrophobicContact CD2-CB 4.18Å; L93-P255 HydrophobicContact CD2-CG 4.47Å
94	T	95.7	Very high	92.8	Very high	1 Å²	1	30.3 Å²	30.3	1%	0.006	18%	0.178	C	C	.	.	H	α-helix	trans	-57.8	-39.8	178	-44.2	0	0	0	0	111.9	A92 I97 I98 S256 T259 F260 L265	A92-T94 PolarHBondContact O-N 3.49Å; A92-T94 VanDerWaalsContact O-N 3.12Å; T94-I97 PolarHBondContact O-N 3.3Å; T94-I98 HydrophobicContact CG2-CD1 4.15Å; T94-I98 WeakPolarHBondContact O-CG1 3.32Å; T94-I98 PolarHBondContact O-N 3.35Å; T94-I98 VanDerWaalsContact O-N 3.12Å; T94-S256 PolarHBondContact OG1-N 2.9Å; T94-S256 PolarHBondContact OG1-O 3.36Å; T94-T259 WeakPolarHBondContact CB-OG1 3.41Å; T94-F260 HydrophobicContact CG2-CB 3.68Å; T94-F260 HydrophobicContact CG2-CD2 3.76Å; T94-F260 HydrophobicContact CG2-CG 4.23Å; T94-L265 HydrophobicContact CG2-CD2 3.72Å
95	F	95.8	Very high	93	Very high	1 Å²	1	34.5 Å²	34.5	0%	0.004	20%	0.196	C	C	.	.	H	α-helix	trans	-63.6	-45.5	176.2	-178.1	-82.4	0	0	0	110.8	F79 V82 L83 N86 A92 L93 I97 I98 W99 L265 A268 A269 Q272	F79-F95 AromaticContact CE2-CE1 3.89Å; F79-F95 HydrophobicContact CE2-CE1 3.89Å; F79-F95 HydrophobicContact CZ-CE1 4.27Å; V82-F95 HydrophobicContact CG1-CE2 4.04Å; V82-F95 HydrophobicContact CG1-CZ 3.85Å; L83-F95 HydrophobicContact CD1-CB 3.68Å; L83-F95 HydrophobicContact CD1-CD1 3.32Å; L83-F95 HydrophobicContact CD1-CE1 4.15Å; L83-F95 HydrophobicContact CD1-CG 3.68Å; N86-F95 HydrophobicContact CB-CD2 3.63Å; N86-F95 HydrophobicContact CB-CE2 4.01Å; A92-F95 WeakPolarHBondContact O-CB 3.41Å; A92-F95 PolarHBondContact O-N 3.46Å; L93-F95 VanDerWaalsContact C-N 3.26Å; L93-F95 PolarHBondContact O-N 3.48Å; F95-I97 VanDerWaalsContact C-N 3.34Å; F95-I97 PolarHBondContact O-N 2.83Å; F95-I98 PolarHBondContact O-N 3.1Å; F95-W99 HydrophobicContact CD1-CB 4.17Å; F95-W99 HydrophobicContact CE1-CB 3.97Å; F95-W99 HydrophobicContact CE1-CG 4.16Å; F95-W99 WeakPolarHBondContact O-CB 3.29Å; F95-W99 PolarHBondContact O-N 2.85Å; F95-L265 HydrophobicContact CB-CD1 4.06Å; F95-L265 HydrophobicContact CD2-CD1 3.65Å; F95-L265 HydrophobicContact CG-CD1 4.34Å; F95-A268 HydrophobicContact CE2-CB 4.3Å; F95-A269 HydrophobicContact CD2-CB 4.32Å; F95-A269 HydrophobicContact CE2-CB 4Å; F95-A269 HydrophobicContact CZ-CB 4.26Å; F95-Q272 HydrophobicContact CZ-CB 4.17Å; F95-Q272 HydrophobicContact CZ-CG 4.31Å
96	Y	96.7	Very high	93.2	Very high	12 Å²	12	31.7 Å²	31.7	5%	0.047	18%	0.178	C	C	.	.	H	α-helix	trans	-58.9	-45.2	177.2	-73.5	-39	0	0	0	112.3	F79 L83 L93 I98 W99 V100 L252 L313 S316	F79-Y96 AromaticContact CE1-CE1 3.83Å; F79-Y96 HydrophobicContact CE1-CE1 3.83Å; F79-Y96 HydrophobicContact CZ-CD1 4.11Å; F79-Y96 AromaticContact CZ-CE1 3.76Å; F79-Y96 HydrophobicContact CZ-CE1 3.76Å; L83-Y96 HydrophobicContact CD1-CD1 4.09Å; L83-Y96 HydrophobicContact CD1-CE1 3.94Å; L83-Y96 HydrophobicContact CD2-CE1 3.66Å; L83-Y96 HydrophobicContact CD2-CE2 4.39Å; L83-Y96 WeakPolarHBondContact CD2-OH 3.37Å; L83-Y96 HydrophobicContact CG-CE1 4.47Å; L93-Y96 HydrophobicContact CD1-CD2 4.27Å; L93-Y96 WeakPolarHBondContact O-CB 3.06Å; L93-Y96 PolarHBondContact O-N 2.86Å; L93-Y96 VanDerWaalsContact O-N 3.12Å; Y96-I98 PolarHBondContact O-N 3.08Å; Y96-W99 HydrophobicContact CD1-CE3 4.37Å; Y96-W99 PolarHBondContact O-N 3.29Å; Y96-V100 WeakPolarHBondContact O-CB 3.15Å; Y96-V100 VanDerWaalsContact O-CG2 3.29Å; Y96-V100 WeakPolarHBondContact O-CG2 3.27Å; Y96-V100 PolarHBondContact O-N 3.47Å; Y96-L252 HydrophobicContact CE2-CB 4.14Å; Y96-L252 HydrophobicContact CE2-CD2 4.37Å; Y96-L313 HydrophobicContact CD1-CD1 4.46Å; Y96-L313 HydrophobicContact CE1-CD1 3.83Å; Y96-L313 HydrophobicContact CE2-CD1 4.01Å; Y96-S316 PolarHBondContact OH-OG 3.06Å
97	I	97	Very high	93.5	Very high	54 Å²	54	30.1 Å²	30.1	28%	0.277	17%	0.17	S	C	.	.	H	α-helix	trans	-57.7	-51.3	178.8	-67.6	169.3	0	0	0	109.7	L93 T94 F95 V100 L101 W257 F260	L93-I97 HydrophobicContact CD1-CG1 4.38Å; L93-I97 HydrophobicContact CD2-CD1 4.5Å; L93-I97 HydrophobicContact CG-CD1 4.04Å; L93-I97 HydrophobicContact CG-CG1 4.33Å; L93-I97 WeakPolarHBondContact O-CG1 3.3Å; L93-I97 PolarHBondContact O-N 2.97Å; T94-I97 PolarHBondContact O-N 3.3Å; F95-I97 VanDerWaalsContact C-N 3.34Å; F95-I97 PolarHBondContact O-N 2.83Å; I97-V100 PolarHBondContact O-N 3.47Å; I97-L101 HydrophobicContact CG2-CD1 4.07Å; I97-L101 VanDerWaalsContact O-CG 3.27Å; I97-L101 WeakPolarHBondContact O-CG 3.23Å; I97-L101 PolarHBondContact O-N 3Å; I97-W257 HydrophobicContact CD1-CH2 3.93Å; I97-W257 HydrophobicContact CD1-CZ3 4.19Å; I97-F260 HydrophobicContact CG2-CE2 4.41Å
98	I	96	Very high	93.9	Very high	0 Å²	0	30.1 Å²	30.1	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-65.2	-46	-178.8	-64.4	164.9	0	0	0	110.9	T94 F95 Y96 V100 L101 I102 F260 L265 W266 A269	T94-I98 HydrophobicContact CG2-CD1 4.15Å; T94-I98 WeakPolarHBondContact O-CG1 3.32Å; T94-I98 PolarHBondContact O-N 3.35Å; T94-I98 VanDerWaalsContact O-N 3.12Å; F95-I98 PolarHBondContact O-N 3.1Å; Y96-I98 PolarHBondContact O-N 3.08Å; I98-V100 VanDerWaalsContact C-N 3.31Å; I98-V100 PolarHBondContact O-N 2.91Å; I98-L101 WeakPolarHBondContact O-CA 3.4Å; I98-L101 WeakPolarHBondContact O-CB 3.46Å; I98-L101 PolarHBondContact O-N 2.87Å; I98-I102 HydrophobicContact CG2-CG1 4.32Å; I98-I102 WeakPolarHBondContact O-CG1 3.34Å; I98-I102 PolarHBondContact O-N 3.33Å; I98-F260 HydrophobicContact CD1-CD2 4Å; I98-F260 HydrophobicContact CD1-CE2 4.33Å; I98-F260 HydrophobicContact CG1-CD2 4.04Å; I98-F260 HydrophobicContact CG1-CE2 3.9Å; I98-L265 HydrophobicContact CD1-CD2 3.45Å; I98-L265 VanDerWaalsContact CD1-CD2 3.45Å; I98-L265 HydrophobicContact CD1-CG 3.76Å; I98-W266 HydrophobicContact CD1-CD2 4.25Å; I98-W266 HydrophobicContact CD1-CG 4.29Å; I98-W266 HydrophobicContact CD1-CZ2 4.32Å; I98-W266 HydrophobicContact CG1-CD2 4.3Å; I98-W266 HydrophobicContact CG1-CH2 4.44Å; I98-W266 HydrophobicContact CG1-CZ2 3.97Å; I98-W266 HydrophobicContact CG2-CB 4.46Å; I98-W266 HydrophobicContact CG2-CD2 3.57Å; I98-W266 HydrophobicContact CG2-CE3 3.52Å; I98-W266 HydrophobicContact CG2-CG 4.01Å; I98-W266 HydrophobicContact CG2-CH2 4.39Å; I98-W266 HydrophobicContact CG2-CZ2 4.44Å; I98-W266 HydrophobicContact CG2-CZ3 3.95Å; I98-A269 HydrophobicContact CB-CB 4.19Å; I98-A269 HydrophobicContact CG2-CB 3.67Å
99	W	96	Very high	94.6	Very high	6 Å²	6	26.8 Å²	26.8	2%	0.023	15%	0.152	C	C	.	.	H	α-helix	trans	-60.1	-38.1	179	171.9	81.9	0	0	0	112.6	F79 F95 Y96 I102 L103 A269 N273 D276 N309	F79-W99 HydrophobicContact CD2-CZ2 4.22Å; F79-W99 AromaticContact CE2-CD2 3.82Å; F79-W99 HydrophobicContact CE2-CD2 3.82Å; F79-W99 AromaticContact CE2-CE2 3.41Å; F79-W99 VanDerWaalsContact CE2-CE2 3.41Å; F79-W99 HydrophobicContact CE2-CE3 4.31Å; F79-W99 HydrophobicContact CE2-CG 4.25Å; F79-W99 AromaticContact CE2-CH2 3.99Å; F79-W99 HydrophobicContact CE2-CH2 3.99Å; F79-W99 AromaticContact CE2-CZ2 3.51Å; F79-W99 HydrophobicContact CE2-CZ2 3.51Å; F79-W99 HydrophobicContact CE2-CZ3 4.39Å; F79-W99 AromaticContact CE2-NE1 3.63Å; F79-W99 HydrophobicContact CZ-CD2 4.15Å; F79-W99 HydrophobicContact CZ-CE3 4.17Å; F79-W99 AromaticContact CZ-CH2 3.88Å; F79-W99 HydrophobicContact CZ-CH2 3.88Å; F79-W99 AromaticContact CZ-CZ2 3.9Å; F79-W99 HydrophobicContact CZ-CZ2 3.9Å; F79-W99 HydrophobicContact CZ-CZ3 4.05Å; F95-W99 HydrophobicContact CD1-CB 4.17Å; F95-W99 HydrophobicContact CE1-CB 3.97Å; F95-W99 HydrophobicContact CE1-CG 4.16Å; F95-W99 WeakPolarHBondContact O-CB 3.29Å; F95-W99 PolarHBondContact O-N 2.85Å; Y96-W99 HydrophobicContact CD1-CE3 4.37Å; Y96-W99 PolarHBondContact O-N 3.29Å; W99-I102 PolarHBondContact O-N 3.47Å; W99-L103 PolarHBondContact O-N 3.44Å; W99-L103 VanDerWaalsContact O-N 3.12Å; W99-A269 HydrophobicContact CB-CB 4.11Å; W99-N273 VanDerWaalsContact CD1-CB 3.49Å; W99-N273 HydrophobicContact CG-CB 4.42Å; W99-N273 PolarHBondContact NE1-ND2 2.97Å; W99-D276 PolarHBondContact NE1-OD2 3.47Å; W99-N309 VanDerWaalsContact CH2-CA 3.5Å; W99-N309 HydrophobicContact CH2-CB 3.29Å; W99-N309 WeakPolarHBondContact CH2-ND2 3.34Å; W99-N309 WeakPolarHBondContact CH2-O 3.35Å; W99-N309 HydrophobicContact CZ2-CB 3.68Å; W99-N309 VanDerWaalsContact CZ2-ND2 3.33Å; W99-N309 WeakPolarHBondContact CZ2-ND2 3.15Å; W99-N309 VanDerWaalsContact CZ2-OD1 3.25Å; W99-N309 WeakPolarHBondContact CZ2-OD1 3.05Å; W99-N309 HydrophobicContact CZ3-CB 3.99Å
100	V	97.6	Very high	95.6	Very high	58 Å²	58	22 Å²	22	35%	0.352	12%	0.118	S	C	.	.	H	α-helix	trans	-69.5	-39.1	171.8	171.6	0	0	0	0	111.5	Y96 I97 I98 I102 L103 F104	Y96-V100 WeakPolarHBondContact O-CB 3.15Å; Y96-V100 VanDerWaalsContact O-CG2 3.29Å; Y96-V100 WeakPolarHBondContact O-CG2 3.27Å; Y96-V100 PolarHBondContact O-N 3.47Å; I97-V100 PolarHBondContact O-N 3.47Å; I98-V100 VanDerWaalsContact C-N 3.31Å; I98-V100 PolarHBondContact O-N 2.91Å; V100-I102 VanDerWaalsContact C-N 3.33Å; V100-I102 PolarHBondContact O-N 2.9Å; V100-L103 VanDerWaalsContact O-CB 3.31Å; V100-L103 WeakPolarHBondContact O-CB 3.23Å; V100-L103 PolarHBondContact O-N 3.36Å; V100-F104 HydrophobicContact CG1-CD2 4.17Å; V100-F104 HydrophobicContact CG1-CE2 3.89Å; V100-F104 VanDerWaalsContact O-CD2 3.27Å; V100-F104 WeakPolarHBondContact O-CD2 3.42Å; V100-F104 PolarHBondContact O-N 3.38Å
101	L	97.1	Very high	96.5	Very high	60 Å²	60	20.4 Å²	20.4	31%	0.314	10%	0.101	S	C	.	.	H	α-helix	trans	-60.7	-44.8	173.6	-69.6	170.2	0	0	0	110.8	I97 I98 L103 F104 F105 W266	I97-L101 HydrophobicContact CG2-CD1 4.07Å; I97-L101 VanDerWaalsContact O-CG 3.27Å; I97-L101 WeakPolarHBondContact O-CG 3.23Å; I97-L101 PolarHBondContact O-N 3Å; I98-L101 WeakPolarHBondContact O-CA 3.4Å; I98-L101 WeakPolarHBondContact O-CB 3.46Å; I98-L101 PolarHBondContact O-N 2.87Å; L101-L103 VanDerWaalsContact C-N 3.28Å; L101-L103 PolarHBondContact O-N 2.89Å; L101-F104 PolarHBondContact O-N 3.33Å; L101-F104 VanDerWaalsContact O-N 3.17Å; L101-F105 HydrophobicContact CB-CD2 4.24Å; L101-F105 HydrophobicContact CD2-CD2 4.3Å; L101-F105 HydrophobicContact CD2-CE2 3.84Å; L101-F105 WeakPolarHBondContact O-CB 3.5Å; L101-F105 WeakPolarHBondContact O-CD2 3.24Å; L101-F105 PolarHBondContact O-N 3.45Å; L101-W266 HydrophobicContact CD1-CH2 4.31Å
102	I	96.1	Very high	96.9	Very high	6 Å²	6	20.4 Å²	20.4	3%	0.031	10%	0.101	C	C	.	.	H	α-helix	trans	-60.1	-38.3	177.1	-61	-60.2	0	0	0	111.5	I98 W99 V100 F104 F105 W106 S107 W266 A270 N273	I98-I102 HydrophobicContact CG2-CG1 4.32Å; I98-I102 WeakPolarHBondContact O-CG1 3.34Å; I98-I102 PolarHBondContact O-N 3.33Å; W99-I102 PolarHBondContact O-N 3.47Å; V100-I102 VanDerWaalsContact C-N 3.33Å; V100-I102 PolarHBondContact O-N 2.9Å; I102-F104 VanDerWaalsContact C-N 3.29Å; I102-F104 PolarHBondContact O-N 3.35Å; I102-F105 PolarHBondContact O-N 3.49Å; I102-W106 HydrophobicContact CG2-CB 3.62Å; I102-W106 HydrophobicContact CG2-CG 4.19Å; I102-W106 WeakPolarHBondContact O-CA 3.44Å; I102-W106 VanDerWaalsContact O-CB 3.27Å; I102-W106 WeakPolarHBondContact O-CB 3.38Å; I102-W106 PolarHBondContact O-N 2.83Å; I102-S107 PolarHBondContact O-N 2.69Å; I102-W266 HydrophobicContact CD1-CE3 4.23Å; I102-W266 HydrophobicContact CD1-CZ3 4.41Å; I102-A270 HydrophobicContact CD1-CB 4.04Å; I102-A270 HydrophobicContact CG1-CB 4.01Å; I102-A270 HydrophobicContact CG2-CB 4.07Å; I102-N273 HydrophobicContact CB-CB 4.25Å; I102-N273 HydrophobicContact CG2-CB 3.97Å
103	L	97.7	Very high	97.1	Very high	5 Å²	5	20.3 Å²	20.3	3%	0.026	10%	0.1	C	C	.	.	I	π-helix	trans	-50.7	-50.1	174.6	172	64.6	0	0	0	111.9	W99 V100 L101 S107 I108 N273 T277 P305 I306 N309	W99-L103 PolarHBondContact O-N 3.44Å; W99-L103 VanDerWaalsContact O-N 3.12Å; V100-L103 VanDerWaalsContact O-CB 3.31Å; V100-L103 WeakPolarHBondContact O-CB 3.23Å; V100-L103 PolarHBondContact O-N 3.36Å; L101-L103 VanDerWaalsContact C-N 3.28Å; L101-L103 PolarHBondContact O-N 2.89Å; L103-S107 PolarHBondContact O-N 3.4Å; L103-I108 HydrophobicContact CD1-CD1 4.09Å; L103-I108 HydrophobicContact CD1-CG1 3.92Å; L103-I108 HydrophobicContact CG-CD1 3.94Å; L103-I108 HydrophobicContact CG-CG1 4.24Å; L103-I108 WeakPolarHBondContact O-CB 3.32Å; L103-I108 VanDerWaalsContact O-CG1 3.3Å; L103-I108 WeakPolarHBondContact O-CG1 3.48Å; L103-I108 PolarHBondContact O-N 3.01Å; L103-N273 VanDerWaalsContact CA-OD1 3.27Å; L103-N273 WeakPolarHBondContact CA-OD1 3.44Å; L103-N273 PolarHBondContact N-OD1 2.93Å; L103-T277 HydrophobicContact CD1-CG2 3.91Å; L103-P305 HydrophobicContact CD1-CB 3.68Å; L103-P305 HydrophobicContact CD1-CG 4.17Å; L103-I306 HydrophobicContact CD2-CG1 4.03Å; L103-N309 HydrophobicContact CD2-CB 4.47Å; L103-N309 WeakPolarHBondContact CD2-ND2 3.47Å
104	F	97.5	Very high	97.1	Very high	82 Å²	82	18.5 Å²	18.5	36%	0.36	9%	0.09	S	C	.	.	I	π-helix	trans	-79.3	-32.3	-177.1	-70.1	-77.9	0	0	0	113.9	V100 L101 I102 I108 P109 F302 I306	V100-F104 HydrophobicContact CG1-CD2 4.17Å; V100-F104 HydrophobicContact CG1-CE2 3.89Å; V100-F104 VanDerWaalsContact O-CD2 3.27Å; V100-F104 WeakPolarHBondContact O-CD2 3.42Å; V100-F104 PolarHBondContact O-N 3.38Å; L101-F104 PolarHBondContact O-N 3.33Å; L101-F104 VanDerWaalsContact O-N 3.17Å; I102-F104 VanDerWaalsContact C-N 3.29Å; I102-F104 PolarHBondContact O-N 3.35Å; F104-I108 HydrophobicContact CD1-CD1 3.68Å; F104-I108 HydrophobicContact CE1-CD1 3.89Å; F104-I108 HydrophobicContact CG-CD1 4.35Å; F104-P109 VanDerWaalsContact O-CD 3.26Å; F104-P109 WeakPolarHBondContact O-CD 3.23Å; F104-F302 HydrophobicContact CD1-CD1 4.42Å; F104-F302 HydrophobicContact CD1-CE1 4.17Å; F104-F302 HydrophobicContact CE1-CD1 4.13Å; F104-F302 HydrophobicContact CE1-CE1 4.27Å; F104-I306 HydrophobicContact CE1-CD1 4.47Å; F104-I306 HydrophobicContact CZ-CD1 4.29Å
105	F	96.6	Very high	97.3	Very high	88 Å²	88	18.5 Å²	18.5	39%	0.386	9%	0.09	S	C	.	.	I	π-helix	trans	-98	-8.8	-173.1	-68.3	-64.8	0	0	0	114.6	L101 I102 L483 L487 V488	L101-F105 HydrophobicContact CB-CD2 4.24Å; L101-F105 HydrophobicContact CD2-CD2 4.3Å; L101-F105 HydrophobicContact CD2-CE2 3.84Å; L101-F105 WeakPolarHBondContact O-CB 3.5Å; L101-F105 WeakPolarHBondContact O-CD2 3.24Å; L101-F105 PolarHBondContact O-N 3.45Å; I102-F105 PolarHBondContact O-N 3.49Å; F105-L483 HydrophobicContact CD1-CD1 4.29Å; F105-L483 HydrophobicContact CD1-CD2 3.81Å; F105-L483 HydrophobicContact CE1-CD2 4.32Å; F105-L487 HydrophobicContact CB-CD2 3.91Å; F105-L487 HydrophobicContact CD1-CD2 4.12Å; F105-L487 HydrophobicContact CG-CD2 4.34Å; F105-V488 VanDerWaalsContact O-CG2 3.3Å; F105-V488 WeakPolarHBondContact O-CG2 3.45Å
106	W	94.6	Very high	97.4	Very high	6 Å²	6	18.4 Å²	18.4	2%	0.023	9%	0.09	C	C	.	.	I	π-helix	trans	-129.4	-65	177.9	-177.2	-61.1	0	0	0	112	I102 P109 I110 V443 V488 Q491 S492 L495	I102-W106 HydrophobicContact CG2-CB 3.62Å; I102-W106 HydrophobicContact CG2-CG 4.19Å; I102-W106 WeakPolarHBondContact O-CA 3.44Å; I102-W106 VanDerWaalsContact O-CB 3.27Å; I102-W106 WeakPolarHBondContact O-CB 3.38Å; I102-W106 PolarHBondContact O-N 2.83Å; W106-P109 VanDerWaalsContact O-CD 3.31Å; W106-P109 WeakPolarHBondContact O-CD 3.39Å; W106-I110 VanDerWaalsContact NE1-CD1 3.33Å; W106-I110 PolarHBondContact O-N 3.37Å; W106-V443 HydrophobicContact CH2-CG1 4.14Å; W106-V443 HydrophobicContact CZ2-CG1 4.27Å; W106-V488 HydrophobicContact CD2-CG1 4.32Å; W106-V488 HydrophobicContact CG-CG1 4.41Å; W106-Q491 HydrophobicContact CE3-CB 3.43Å; W106-Q491 VanDerWaalsContact CE3-CB 3.43Å; W106-Q491 HydrophobicContact CE3-CG 4.25Å; W106-Q491 HydrophobicContact CH2-CB 4.23Å; W106-Q491 VanDerWaalsContact CZ3-C 3.44Å; W106-Q491 HydrophobicContact CZ3-CB 3.19Å; W106-Q491 HydrophobicContact CZ3-CG 4.4Å; W106-S492 VanDerWaalsContact CH2-CA 3.49Å; W106-S492 WeakPolarHBondContact CH2-OG 3.42Å; W106-S492 WeakPolarHBondContact CZ2-OG 3.24Å; W106-L495 HydrophobicContact CE3-CD1 4.47Å; W106-L495 HydrophobicContact CH2-CD1 3.34Å; W106-L495 HydrophobicContact CH2-CG 3.99Å; W106-L495 HydrophobicContact CZ2-CD1 4.28Å; W106-L495 HydrophobicContact CZ3-CD1 3.42Å; W106-L495 VanDerWaalsContact CZ3-CD1 3.42Å; W106-L495 HydrophobicContact CZ3-CG 3.88Å
107	S	97.1	Very high	97.4	Very high	0 Å²	0	17.9 Å²	17.9	0%	0	9%	0.088	C	C	.	.	I	π-helix	trans	-71.8	-47.8	-164.4	-61	0	0	0	0	112.4	I102 L103 I110 L111 N273 T277	I102-S107 PolarHBondContact O-N 2.69Å; L103-S107 PolarHBondContact O-N 3.4Å; S107-I110 PolarHBondContact O-N 2.99Å; S107-L111 WeakPolarHBondContact O-CB 3.28Å; S107-L111 VanDerWaalsContact O-CG 3.23Å; S107-L111 WeakPolarHBondContact O-CG 3.29Å; S107-L111 PolarHBondContact O-N 2.96Å; S107-N273 VanDerWaalsContact CB-OD1 3.28Å; S107-N273 WeakPolarHBondContact CB-OD1 2.78Å; S107-N273 PolarHBondContact OG-OD1 3.3Å; S107-T277 WeakPolarHBondContact CB-OG1 3.42Å; S107-T277 PolarHBondContact OG-OG1 3.33Å
108	I	98	Very high	97.4	Very high	2 Å²	2	15.3 Å²	15.3	1%	0.01	8%	0.075	C	C	.	.	H	α-helix	trans	-58.2	-47.7	176.2	-69.6	175.2	0	0	0	111.6	L103 F104 I110 L111 I112 S301 F302 P305	L103-I108 HydrophobicContact CD1-CD1 4.09Å; L103-I108 HydrophobicContact CD1-CG1 3.92Å; L103-I108 HydrophobicContact CG-CD1 3.94Å; L103-I108 HydrophobicContact CG-CG1 4.24Å; L103-I108 WeakPolarHBondContact O-CB 3.32Å; L103-I108 VanDerWaalsContact O-CG1 3.3Å; L103-I108 WeakPolarHBondContact O-CG1 3.48Å; L103-I108 PolarHBondContact O-N 3.01Å; F104-I108 HydrophobicContact CD1-CD1 3.68Å; F104-I108 HydrophobicContact CE1-CD1 3.89Å; F104-I108 HydrophobicContact CG-CD1 4.35Å; I108-I110 VanDerWaalsContact C-N 3.31Å; I108-I110 PolarHBondContact O-N 3.42Å; I108-L111 PolarHBondContact O-N 2.94Å; I108-I112 HydrophobicContact CG2-CD1 3.92Å; I108-I112 HydrophobicContact CG2-CG1 4.4Å; I108-I112 VanDerWaalsContact O-CG1 3.28Å; I108-I112 WeakPolarHBondContact O-CG1 3.36Å; I108-I112 PolarHBondContact O-N 2.98Å; I108-S301 WeakPolarHBondContact CG1-O 3.47Å; I108-F302 HydrophobicContact CD1-CD1 3.73Å; I108-F302 HydrophobicContact CD1-CE1 4.12Å; I108-F302 HydrophobicContact CD1-CG 4.22Å; I108-F302 HydrophobicContact CG2-CD1 4.1Å; I108-F302 HydrophobicContact CG2-CD2 3.92Å; I108-F302 HydrophobicContact CG2-CE1 3.88Å; I108-F302 HydrophobicContact CG2-CE2 3.69Å; I108-F302 HydrophobicContact CG2-CG 4.12Å; I108-F302 HydrophobicContact CG2-CZ 3.67Å; I108-P305 HydrophobicContact CG1-CG 3.94Å
109	P	98.2	Very high	97.4	Very high	2 Å²	2	15.4 Å²	15.4	1%	0.013	8%	0.075	C	C	.	.	H	α-helix	trans	-52.3	-44.1	174.6	-30.9	33.4	0	0	0	114.7	F104 W106 W480 L483 I484 V488	F104-P109 VanDerWaalsContact O-CD 3.26Å; F104-P109 WeakPolarHBondContact O-CD 3.23Å; W106-P109 VanDerWaalsContact O-CD 3.31Å; W106-P109 WeakPolarHBondContact O-CD 3.39Å; P109-W480 PolarHBondContact O-NE1 3.48Å; P109-W480 VanDerWaalsContact O-NE1 3.17Å; P109-L483 HydrophobicContact CG-CB 4.26Å; P109-L483 HydrophobicContact CG-CD1 4.24Å; P109-I484 HydrophobicContact CB-CD1 4.14Å; P109-V488 HydrophobicContact CB-CG2 4.14Å; P109-V488 HydrophobicContact CG-CG2 4.46Å
110	I	98.2	Very high	97.3	Very high	0 Å²	0	15.2 Å²	15.2	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-70.8	-44.7	177.5	-67.1	174.9	0	0	0	110.9	W106 S107 I108 I112 V113 E114 S279 F449 I484 V488	W106-I110 VanDerWaalsContact NE1-CD1 3.33Å; W106-I110 PolarHBondContact O-N 3.37Å; S107-I110 PolarHBondContact O-N 2.99Å; I108-I110 VanDerWaalsContact C-N 3.31Å; I108-I110 PolarHBondContact O-N 3.42Å; I110-I112 PolarHBondContact O-N 2.91Å; I110-V113 CarbonylContact O-C 3.5Å; I110-V113 WeakPolarHBondContact O-CA 3.41Å; I110-V113 WeakPolarHBondContact O-CB 3.44Å; I110-V113 PolarHBondContact O-N 2.83Å; I110-E114 HydrophobicContact CG2-CG 4.37Å; I110-E114 PolarHBondContact O-N 2.68Å; I110-S279 WeakPolarHBondContact CB-OG 3.24Å; I110-S279 WeakPolarHBondContact CG2-OG 3.33Å; I110-F449 HydrophobicContact CG2-CB 4.47Å; I110-F449 HydrophobicContact CG2-CD2 4.3Å; I110-I484 HydrophobicContact CG1-CD1 4.31Å; I110-V488 HydrophobicContact CD1-CG1 3.67Å; I110-V488 HydrophobicContact CG1-CG1 3.85Å
111	L	98.4	Very high	97.2	Very high	4 Å²	4	12.4 Å²	12.4	2%	0.021	6%	0.058	C	C	.	.	H	α-helix	trans	-58.9	-37	179.7	-71.8	169.4	0	0	0	111.6	S107 I108 V113 E114 Y115 M284 P305	S107-L111 WeakPolarHBondContact O-CB 3.28Å; S107-L111 VanDerWaalsContact O-CG 3.23Å; S107-L111 WeakPolarHBondContact O-CG 3.29Å; S107-L111 PolarHBondContact O-N 2.96Å; I108-L111 PolarHBondContact O-N 2.94Å; L111-V113 VanDerWaalsContact C-N 3.3Å; L111-V113 PolarHBondContact O-N 3.43Å; L111-E114 WeakPolarHBondContact O-CB 3.26Å; L111-E114 PolarHBondContact O-N 2.88Å; L111-E114 VanDerWaalsContact O-N 3.14Å; L111-Y115 HydrophobicContact CB-CD2 4.48Å; L111-Y115 VanDerWaalsContact O-CD2 3.22Å; L111-Y115 WeakPolarHBondContact O-CD2 3.21Å; L111-Y115 PolarHBondContact O-N 3.31Å; L111-M284 HydrophobicContact CD2-CB 4.41Å; L111-M284 HydrophobicContact CD2-CG 3.75Å; L111-P305 HydrophobicContact CD1-CB 3.75Å; L111-P305 HydrophobicContact CD1-CG 3.7Å
112	I	98.6	Very high	97	Very high	1 Å²	1	10.5 Å²	10.5	1%	0.005	5%	0.046	C	C	.	.	H	α-helix	trans	-57.6	-43.2	171.4	-70.7	166.4	0	0	0	111.2	I108 I110 S116 S301 F302 I466 L476 W480	I108-I112 HydrophobicContact CG2-CD1 3.92Å; I108-I112 HydrophobicContact CG2-CG1 4.4Å; I108-I112 VanDerWaalsContact O-CG1 3.28Å; I108-I112 WeakPolarHBondContact O-CG1 3.36Å; I108-I112 PolarHBondContact O-N 2.98Å; I110-I112 PolarHBondContact O-N 2.91Å; I112-S116 WeakPolarHBondContact O-CB 3.31Å; I112-S116 PolarHBondContact O-N 2.98Å; I112-S116 PolarHBondContact O-OG 3.5Å; I112-S301 WeakPolarHBondContact CA-OG 3.18Å; I112-S301 VanDerWaalsContact CG1-CB 3.42Å; I112-F302 HydrophobicContact CD1-CE2 4.07Å; I112-I466 HydrophobicContact CG2-CD1 3.49Å; I112-I466 VanDerWaalsContact CG2-CD1 3.49Å; I112-L476 HydrophobicContact CD1-CD1 3.82Å; I112-L476 HydrophobicContact CD1-CD2 4.3Å; I112-L476 HydrophobicContact CG2-CD2 3.6Å; I112-W480 HydrophobicContact CG2-CZ2 4.08Å
113	V	98.7	Very high	97	Very high	0 Å²	0	10.2 Å²	10.2	0%	0	5%	0.045	C	C	.	.	H	α-helix	trans	-60.6	-49	174.3	-177	0	0	0	0	109.7	I110 L111 S116 L117 F449 V453 Y461 W480 I484	I110-V113 CarbonylContact O-C 3.5Å; I110-V113 WeakPolarHBondContact O-CA 3.41Å; I110-V113 WeakPolarHBondContact O-CB 3.44Å; I110-V113 PolarHBondContact O-N 2.83Å; L111-V113 VanDerWaalsContact C-N 3.3Å; L111-V113 PolarHBondContact O-N 3.43Å; V113-S116 WeakPolarHBondContact CA-OG 3.27Å; V113-S116 PolarHBondContact O-N 3.46Å; V113-S116 PolarHBondContact O-OG 2.96Å; V113-L117 WeakPolarHBondContact O-CB 3.17Å; V113-L117 PolarHBondContact O-N 2.95Å; V113-F449 HydrophobicContact CG1-CB 4.17Å; V113-F449 HydrophobicContact CG1-CD1 3.9Å; V113-F449 HydrophobicContact CG1-CG 4.44Å; V113-V453 HydrophobicContact CB-CG2 4.33Å; V113-V453 HydrophobicContact CG1-CG2 3.75Å; V113-V453 HydrophobicContact CG2-CG2 3.55Å; V113-Y461 PolarHBondContact O-OH 2.81Å; V113-W480 HydrophobicContact CG2-CH2 4.31Å; V113-W480 HydrophobicContact CG2-CZ2 3.68Å; V113-I484 HydrophobicContact CG2-CD1 3.79Å; V113-I484 HydrophobicContact CG2-CG1 3.94Å
114	E	98.5	Very high	96.9	Very high	0 Å²	0	10 Å²	10	0%	0	4%	0.044	C	C	.	.	H	α-helix	trans	-59.1	-54.1	-178.4	-69.7	-162.1	-124.3	0	0	112.7	I110 L111 S116 L117 G118 G280 G282 I283 M284 T285 S288 F449	I110-E114 HydrophobicContact CG2-CG 4.37Å; I110-E114 PolarHBondContact O-N 2.68Å; L111-E114 WeakPolarHBondContact O-CB 3.26Å; L111-E114 PolarHBondContact O-N 2.88Å; L111-E114 VanDerWaalsContact O-N 3.14Å; E114-S116 VanDerWaalsContact C-N 3.34Å; E114-S116 PolarHBondContact O-N 3.06Å; E114-L117 PolarHBondContact O-N 2.85Å; E114-G118 PolarHBondContact O-N 3.14Å; E114-G280 WeakPolarHBondContact OE1-CA 3.46Å; E114-G280 PolarHBondContact OE1-N 3.24Å; E114-G282 WeakPolarHBondContact OE2-CA 3.4Å; E114-G282 PolarHBondContact OE2-N 2.87Å; E114-I283 PolarHBondContact OE2-N 3.45Å; E114-M284 HydrophobicContact CB-CB 3.87Å; E114-M284 PolarHBondContact OE2-N 3.38Å; E114-T285 VanDerWaalsContact CA-OG1 3.29Å; E114-T285 WeakPolarHBondContact CA-OG1 3.3Å; E114-T285 WeakPolarHBondContact CB-OG1 3.29Å; E114-T285 WeakPolarHBondContact CG-OG1 3.36Å; E114-T285 VanDerWaalsContact O-CA 3.27Å; E114-T285 WeakPolarHBondContact O-CA 3.43Å; E114-T285 PolarHBondContact OE2-N 3Å; E114-T285 PolarHBondContact OE2-OG1 3.14Å; E114-S288 PolarHBondContact O-OG 2.82Å; E114-F449 HydrophobicContact CG-CD1 4.4Å; E114-F449 HydrophobicContact CG-CD2 4.34Å; E114-F449 HydrophobicContact CG-CE1 4.01Å; E114-F449 HydrophobicContact CG-CE2 3.94Å; E114-F449 HydrophobicContact CG-CZ 3.77Å
115	Y	98.2	Very high	96.9	Very high	1 Å²	1	6.2 Å²	6.2	0%	0.004	3%	0.027	C	C	.	.	H	α-helix	trans	-60.8	-42.5	179.3	-81.3	-76.2	0	0	0	112.3	C66 L111 R119 M284 S288 M291 I297 S301 I304	C66-Y115 WeakPolarHBondContact CB-OH 3.2Å; L111-Y115 HydrophobicContact CB-CD2 4.48Å; L111-Y115 VanDerWaalsContact O-CD2 3.22Å; L111-Y115 WeakPolarHBondContact O-CD2 3.21Å; L111-Y115 PolarHBondContact O-N 3.31Å; Y115-R119 WeakPolarHBondContact O-CB 3.49Å; Y115-R119 PolarHBondContact O-N 3.24Å; Y115-M284 HydrophobicContact CD1-CB 4.27Å; Y115-M284 HydrophobicContact CD2-CB 3.93Å; Y115-M284 HydrophobicContact CD2-CG 4.32Å; Y115-M284 HydrophobicContact CE1-CB 4.11Å; Y115-M284 HydrophobicContact CE1-CG 4.37Å; Y115-M284 HydrophobicContact CE1-SD 4.17Å; Y115-M284 HydrophobicContact CE2-CB 3.76Å; Y115-M284 HydrophobicContact CE2-CG 3.67Å; Y115-M284 HydrophobicContact CE2-SD 4.22Å; Y115-M284 HydrophobicContact CG-CB 4.16Å; Y115-M284 PolarHBondContact OH-SD 3.45Å; Y115-S288 VanDerWaalsContact O-CB 3.26Å; Y115-S288 WeakPolarHBondContact O-CB 3.38Å; Y115-S288 PolarHBondContact O-OG 3.42Å; Y115-S288 VanDerWaalsContact O-OG 3.1Å; Y115-M291 HydrophobicContact CD1-SD 4.4Å; Y115-M291 HydrophobicContact CE1-CE 4.28Å; Y115-I297 HydrophobicContact CD1-CG2 4.37Å; Y115-I297 HydrophobicContact CG-CB 4.47Å; Y115-S301 WeakPolarHBondContact CD2-OG 3.44Å; Y115-I304 WeakPolarHBondContact OH-CD1 3.2Å
116	S	97.8	Very high	97	Very high	0 Å²	0	2 Å²	2	0%	0	1%	0.009	C	C	.	.	H	α-helix	trans	-69.2	-42.9	179.7	58.1	0	0	0	0	112	I112 V113 E114 F120 Y461	I112-S116 WeakPolarHBondContact O-CB 3.31Å; I112-S116 PolarHBondContact O-N 2.98Å; I112-S116 PolarHBondContact O-OG 3.5Å; V113-S116 WeakPolarHBondContact CA-OG 3.27Å; V113-S116 PolarHBondContact O-N 3.46Å; V113-S116 PolarHBondContact O-OG 2.96Å; E114-S116 VanDerWaalsContact C-N 3.34Å; E114-S116 PolarHBondContact O-N 3.06Å; S116-F120 WeakPolarHBondContact O-CB 3.48Å; S116-F120 PolarHBondContact O-N 2.9Å; S116-Y461 VanDerWaalsContact OG-CE1 3.26Å; S116-Y461 WeakPolarHBondContact OG-CE1 3.46Å; S116-Y461 PolarHBondContact OG-OH 3.03Å
117	L	98.1	Very high	97	Very high	0 Å²	0	1.8 Å²	1.8	0%	0	1%	0.008	C	C	.	.	H	α-helix	trans	-60.8	-49.6	179.8	-178	67	0	0	0	110.6	V113 E114 T121 A128 F129 F132 T285 F449 L452 Y461	V113-L117 WeakPolarHBondContact O-CB 3.17Å; V113-L117 PolarHBondContact O-N 2.95Å; E114-L117 PolarHBondContact O-N 2.85Å; L117-T121 HydrophobicContact CD1-CG2 3.93Å; L117-T121 WeakPolarHBondContact O-CB 3.42Å; L117-T121 WeakPolarHBondContact O-CG2 3.5Å; L117-T121 PolarHBondContact O-N 2.81Å; L117-T121 PolarHBondContact O-OG1 3.21Å; L117-A128 HydrophobicContact CD1-CB 4.08Å; L117-A128 HydrophobicContact CD2-CB 4.06Å; L117-A128 HydrophobicContact CG-CB 3.95Å; L117-F129 HydrophobicContact CD2-CD2 4.39Å; L117-F129 HydrophobicContact CD2-CE2 4.07Å; L117-F132 HydrophobicContact CD1-CD2 4.12Å; L117-F132 HydrophobicContact CD1-CE2 3.35Å; L117-F132 HydrophobicContact CD1-CZ 3.93Å; L117-T285 HydrophobicContact CB-CG2 4.42Å; L117-T285 HydrophobicContact CD2-CG2 4.02Å; L117-T285 HydrophobicContact CG-CG2 4.24Å; L117-F449 HydrophobicContact CD2-CD1 4.23Å; L117-F449 HydrophobicContact CD2-CE1 3.79Å; L117-L452 HydrophobicContact CD1-CD1 4.15Å; L117-L452 HydrophobicContact CD1-CD2 4.33Å; L117-L452 HydrophobicContact CD2-CD1 4.21Å; L117-Y461 PolarHBondContact N-OH 3.27Å
118	G	96.9	Very high	97	Very high	0 Å²	0	1.8 Å²	1.8	0%	0	1%	0.008	C	C	.	.	H	α-helix	trans	-69.3	-43.2	-178.4	0	0	0	0	0	113	E114 F120 R122 T285 S288 T289	E114-G118 PolarHBondContact O-N 3.14Å; G118-F120 PolarHBondContact O-N 2.65Å; G118-R122 WeakPolarHBondContact O-CA 3.23Å; G118-R122 PolarHBondContact O-N 2.59Å; G118-T285 VanDerWaalsContact CA-O 3.28Å; G118-T285 WeakPolarHBondContact CA-O 3.31Å; G118-S288 WeakPolarHBondContact CA-OG 3.47Å; G118-T289 WeakPolarHBondContact O-CA 3.5Å
119	R	94.9	Very high	97	Very high	3 Å²	3	1.8 Å²	1.8	1%	0.011	1%	0.008	C	C	.	.	H	α-helix	trans	-62.7	-42.1	175.7	-172.2	-177.6	63.5	141.7	6	112.4	Y115 R122 S288 S292 R293 S295 I297 F469	Y115-R119 WeakPolarHBondContact O-CB 3.49Å; Y115-R119 PolarHBondContact O-N 3.24Å; R119-R122 WeakPolarHBondContact O-CG 3.23Å; R119-S288 VanDerWaalsContact CA-O 3.28Å; R119-S288 WeakPolarHBondContact CA-O 3.29Å; R119-S288 PolarHBondContact N-O 2.78Å; R119-S288 PolarHBondContact N-OG 2.94Å; R119-S292 VanDerWaalsContact CD-O 3.25Å; R119-S292 WeakPolarHBondContact CD-O 3.4Å; R119-R293 PolarHBondContact NH1-O 3.19Å; R119-S295 PolarHBondContact NH1-O 3.01Å; R119-S295 VanDerWaalsContact NH1-O 3.15Å; R119-I297 HydrophobicContact CB-CG2 4.34Å; R119-F469 HydrophobicContact CG-CE1 4.27Å
120	F	94.8	Very high	96.9	Very high	1 Å²	1	1.9 Å²	1.9	0%	0.004	1%	0.008	C	C	.	.	H	α-helix	trans	-74.3	-49.8	-176.8	-175.6	-90.7	0	0	0	111.9	S116 G118 V464 L465 F469 C555 P557 P560	S116-F120 WeakPolarHBondContact O-CB 3.48Å; S116-F120 PolarHBondContact O-N 2.9Å; G118-F120 PolarHBondContact O-N 2.65Å; F120-V464 HydrophobicContact CE2-CG1 4.47Å; F120-V464 HydrophobicContact CZ-CG1 4.46Å; F120-L465 HydrophobicContact CB-CD2 4.12Å; F120-L465 HydrophobicContact CB-CG 4.29Å; F120-L465 HydrophobicContact CD1-CD2 3.67Å; F120-L465 HydrophobicContact CD1-CG 3.77Å; F120-L465 HydrophobicContact CD2-CB 4.2Å; F120-L465 HydrophobicContact CD2-CD2 4.41Å; F120-L465 HydrophobicContact CD2-CG 3.75Å; F120-L465 HydrophobicContact CE1-CD1 4.35Å; F120-L465 HydrophobicContact CE1-CD2 4.15Å; F120-L465 HydrophobicContact CE1-CG 3.96Å; F120-L465 HydrophobicContact CE2-CD1 4.48Å; F120-L465 HydrophobicContact CE2-CG 3.93Å; F120-L465 HydrophobicContact CG-CB 4.33Å; F120-L465 HydrophobicContact CG-CD2 3.82Å; F120-L465 HydrophobicContact CG-CG 3.67Å; F120-L465 HydrophobicContact CZ-CD1 4.27Å; F120-L465 HydrophobicContact CZ-CG 4.03Å; F120-F469 HydrophobicContact CB-CD1 4.43Å; F120-F469 HydrophobicContact CB-CE1 4.34Å; F120-F469 HydrophobicContact CD2-CB 4.1Å; F120-F469 AromaticContact CD2-CD1 3.81Å; F120-F469 HydrophobicContact CD2-CD1 3.81Å; F120-F469 AromaticContact CD2-CD2 3.76Å; F120-F469 HydrophobicContact CD2-CD2 3.76Å; F120-F469 HydrophobicContact CD2-CE1 4.11Å; F120-F469 HydrophobicContact CD2-CE2 4.09Å; F120-F469 AromaticContact CD2-CG 3.61Å; F120-F469 HydrophobicContact CD2-CG 3.61Å; F120-F469 HydrophobicContact CD2-CZ 4.24Å; F120-F469 HydrophobicContact CE2-CB 4.39Å; F120-F469 AromaticContact CE2-CD2 3.89Å; F120-F469 HydrophobicContact CE2-CD2 3.89Å; F120-F469 HydrophobicContact CE2-CE2 4.34Å; F120-F469 HydrophobicContact CE2-CG 4.09Å; F120-C555 HydrophobicContact CD1-CB 3.79Å; F120-C555 HydrophobicContact CD2-CB 4.19Å; F120-C555 HydrophobicContact CE1-CB 3.35Å; F120-C555 HydrophobicContact CE2-CB 3.8Å; F120-C555 HydrophobicContact CG-CB 4.19Å; F120-C555 HydrophobicContact CZ-CB 3.36Å; F120-C555 PolarHBondContact O-N 3.34Å; F120-P557 HydrophobicContact CE1-CB 4.08Å; F120-P560 HydrophobicContact CZ-CB 4.17Å
121	T	94.6	Very high	96.7	Very high	0 Å²	0	3.5 Å²	3.5	0%	0	2%	0.016	C	C	.	.	H	α-helix	trans	-82.4	-23.9	-177	64.7	0	0	0	0	113.1	L117 N123 A128 K131 F132 H553 G554	L117-T121 HydrophobicContact CD1-CG2 3.93Å; L117-T121 WeakPolarHBondContact O-CB 3.42Å; L117-T121 WeakPolarHBondContact O-CG2 3.5Å; L117-T121 PolarHBondContact O-N 2.81Å; L117-T121 PolarHBondContact O-OG1 3.21Å; T121-N123 PolarHBondContact O-N 3.41Å; T121-N123 VanDerWaalsContact O-N 3.15Å; T121-N123 PolarHBondContact O-OD1 3.44Å; T121-N123 PolarHBondContact OG1-N 2.97Å; T121-A128 HydrophobicContact CG2-CB 4.21Å; T121-K131 HydrophobicContact CG2-CD 4.22Å; T121-K131 PolarHBondContact O-NZ 3.16Å; T121-F132 HydrophobicContact CG2-CE2 4.04Å; T121-H553 CarbonylContact O-C 3.57Å; T121-G554 WeakPolarHBondContact O-CA 3.42Å
122	R	93.9	Very high	96.6	Very high	20 Å²	20	3.8 Å²	3.8	8%	0.075	2%	0.017	C	C	.	.			trans	54.2	25.1	-173.5	-55.8	-179.3	68.5	81.5	-7.4	113.9	K53 M55 G118 R119 M291 H553	K53-R122 PolarHBondContact NZ-O 2.72Å; M55-R122 PolarHBondContact SD-NH2 2.85Å; G118-R122 WeakPolarHBondContact O-CA 3.23Å; G118-R122 PolarHBondContact O-N 2.59Å; R119-R122 WeakPolarHBondContact O-CG 3.23Å; R122-M291 PolarHBondContact NH1-O 3.46Å; R122-H553 HydrophobicContact CB-CB 4.22Å
123	N	95.1	Very high	96.5	Very high	0 Å²	0	5.7 Å²	5.7	0%	0	3%	0.025	C	C	.	.	S	Bend	trans	-120.8	161.8	-175.4	-69.4	126.6	0	0	0	114.1	T121 V127 A128 K131 T289 E401 A552 H553	T121-N123 PolarHBondContact O-N 3.41Å; T121-N123 VanDerWaalsContact O-N 3.15Å; T121-N123 PolarHBondContact O-OD1 3.44Å; T121-N123 PolarHBondContact OG1-N 2.97Å; N123-V127 HydrophobicContact CB-CB 3.98Å; N123-V127 HydrophobicContact CB-CG1 3.8Å; N123-A128 HydrophobicContact CB-CB 4.48Å; N123-K131 WeakPolarHBondContact OD1-CE 3.4Å; N123-K131 PolarHBondContact OD1-NZ 3.27Å; N123-T289 WeakPolarHBondContact O-CG2 3.47Å; N123-E401 WeakPolarHBondContact CA-OE1 3.43Å; N123-E401 WeakPolarHBondContact CB-OE1 3.37Å; N123-E401 PolarHBondContact ND2-OE1 3.49Å; N123-A552 WeakPolarHBondContact ND2-CB 3.37Å; N123-H553 PolarHBondContact OD1-O 3.12Å
124	S	96.6	Very high	96.3	Very high	1 Å²	1	7.2 Å²	7.2	1%	0.007	4%	0.04	C	C	.	.			trans	-58	158	168.3	71.2	0	0	0	0	111.2	P126 V127 A128 E401	S124-P126 WeakPolarHBondContact OG-CD 3.19Å; S124-V127 PolarHBondContact O-N 3.36Å; S124-V127 VanDerWaalsContact O-N 3.17Å; S124-A128 VanDerWaalsContact O-CB 3.31Å; S124-A128 WeakPolarHBondContact O-CB 3.48Å; S124-A128 PolarHBondContact O-N 3.5Å; S124-E401 WeakPolarHBondContact CB-OE2 3.28Å; S124-E401 PolarHBondContact N-OE1 3.3Å; S124-E401 VanDerWaalsContact N-OE1 3.14Å; S124-E401 PolarHBondContact N-OE2 2.87Å; S124-E401 PolarHBondContact OG-OE2 2.9Å
125	V	97.7	Very high	96	Very high	1 Å²	1	9.9 Å²	9.9	1%	0.006	5%	0.053	C	C	.	.	H	α-helix	trans	-51.6	-48.5	179.7	-169.5	0	0	0	0	112.3	V127 A128 F129 M144 T285 F449	V125-V127 PolarHBondContact O-N 3.34Å; V125-A128 PolarHBondContact O-N 2.97Å; V125-F129 HydrophobicContact CG1-CD2 3.89Å; V125-F129 HydrophobicContact CG1-CE2 3.81Å; V125-F129 VanDerWaalsContact O-CD2 3.24Å; V125-F129 WeakPolarHBondContact O-CD2 3.38Å; V125-F129 PolarHBondContact O-N 2.95Å; V125-M144 HydrophobicContact CG1-CB 4.43Å; V125-M144 HydrophobicContact CG1-CE 4.42Å; V125-M144 HydrophobicContact CG1-CG 4.42Å; V125-M144 HydrophobicContact CG1-SD 3.56Å; V125-M144 VanDerWaalsContact CG1-SD 3.56Å; V125-T285 HydrophobicContact CG2-CG2 3.88Å; V125-F449 HydrophobicContact CG1-CE1 4.41Å; V125-F449 HydrophobicContact CG1-CZ 4.14Å
126	P	97.7	Very high	95.8	Very high	1 Å²	1	16 Å²	16	1%	0.006	8%	0.08	C	C	.	.	H	α-helix	trans	-57.6	-47.2	176.8	-23.7	33.3	0	0	0	114.6	S124 F129 C130 F138 A142 V145 A398	S124-P126 WeakPolarHBondContact OG-CD 3.19Å; P126-F129 PolarHBondContact O-N 3.42Å; P126-C130 PolarHBondContact O-N 2.85Å; P126-F138 HydrophobicContact CB-CD1 4.35Å; P126-F138 HydrophobicContact CB-CD2 3.71Å; P126-F138 HydrophobicContact CB-CE1 3.98Å; P126-F138 HydrophobicContact CB-CE2 3.3Å; P126-F138 HydrophobicContact CB-CG 4.22Å; P126-F138 HydrophobicContact CB-CZ 3.44Å; P126-F138 VanDerWaalsContact CB-CZ 3.44Å; P126-F138 HydrophobicContact CG-CE2 4.44Å; P126-F138 HydrophobicContact CG-CZ 4.21Å; P126-A142 HydrophobicContact CG-CB 4.34Å; P126-V145 HydrophobicContact CG-CG2 3.59Å; P126-A398 HydrophobicContact CG-CB 4.16Å
127	V	95.9	Very high	95.7	Very high	1 Å²	1	20.3 Å²	20.3	1%	0.006	10%	0.099	C	C	.	.	H	α-helix	trans	-71.9	-36.6	-177.9	173.9	0	0	0	0	111.1	N123 S124 V125 F129 C130 K131 F138 E401 L549 A552	N123-V127 HydrophobicContact CB-CB 3.98Å; N123-V127 HydrophobicContact CB-CG1 3.8Å; S124-V127 PolarHBondContact O-N 3.36Å; S124-V127 VanDerWaalsContact O-N 3.17Å; V125-V127 PolarHBondContact O-N 3.34Å; V127-F129 VanDerWaalsContact C-N 3.34Å; V127-F129 PolarHBondContact O-N 2.83Å; V127-C130 WeakPolarHBondContact O-CB 3.2Å; V127-C130 PolarHBondContact O-N 3.48Å; V127-C130 VanDerWaalsContact O-N 3.16Å; V127-K131 PolarHBondContact O-N 3.2Å; V127-K131 VanDerWaalsContact O-N 3.1Å; V127-F138 HydrophobicContact CG2-CE2 4.15Å; V127-E401 VanDerWaalsContact CB-OE2 3.29Å; V127-E401 WeakPolarHBondContact CB-OE2 3.38Å; V127-E401 HydrophobicContact CG2-CB 4.18Å; V127-E401 WeakPolarHBondContact CG2-OE2 3.19Å; V127-L549 HydrophobicContact CG1-CD2 3.91Å; V127-A552 HydrophobicContact CG1-CB 4.3Å
128	A	96.5	Very high	95.7	Very high	0 Å²	0	20.7 Å²	20.7	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-57.3	-48.4	171.9	0	0	0	0	0	110.2	L117 T121 N123 S124 V125 C130 K131 F132	L117-A128 HydrophobicContact CD1-CB 4.08Å; L117-A128 HydrophobicContact CD2-CB 4.06Å; L117-A128 HydrophobicContact CG-CB 3.95Å; T121-A128 HydrophobicContact CG2-CB 4.21Å; N123-A128 HydrophobicContact CB-CB 4.48Å; S124-A128 VanDerWaalsContact O-CB 3.31Å; S124-A128 WeakPolarHBondContact O-CB 3.48Å; S124-A128 PolarHBondContact O-N 3.5Å; V125-A128 PolarHBondContact O-N 2.97Å; A128-C130 VanDerWaalsContact C-N 3.31Å; A128-C130 PolarHBondContact O-N 3.24Å; A128-K131 WeakPolarHBondContact O-CB 3.32Å; A128-K131 PolarHBondContact O-N 3.38Å; A128-F132 VanDerWaalsContact O-CD2 3.3Å; A128-F132 WeakPolarHBondContact O-CD2 3.39Å
129	F	97.4	Very high	95.7	Very high	1 Å²	1	23.2 Å²	23.2	0%	0.004	11%	0.11	C	C	.	.	H	α-helix	trans	-60.5	-37.3	175.4	-88.6	-109.3	0	0	0	112.9	L117 V125 P126 V127 K131 F132 F133 L140 M144 L448 F449 L452	L117-F129 HydrophobicContact CD2-CD2 4.39Å; L117-F129 HydrophobicContact CD2-CE2 4.07Å; V125-F129 HydrophobicContact CG1-CD2 3.89Å; V125-F129 HydrophobicContact CG1-CE2 3.81Å; V125-F129 VanDerWaalsContact O-CD2 3.24Å; V125-F129 WeakPolarHBondContact O-CD2 3.38Å; V125-F129 PolarHBondContact O-N 2.95Å; P126-F129 PolarHBondContact O-N 3.42Å; V127-F129 VanDerWaalsContact C-N 3.34Å; V127-F129 PolarHBondContact O-N 2.83Å; F129-K131 VanDerWaalsContact C-N 3.29Å; F129-K131 PolarHBondContact O-N 2.96Å; F129-F132 PolarHBondContact O-N 2.74Å; F129-F132 VanDerWaalsContact O-N 3.12Å; F129-F133 HydrophobicContact CB-CD2 4.49Å; F129-F133 AromaticContact CD1-CD2 3.91Å; F129-F133 HydrophobicContact CD1-CD2 3.91Å; F129-F133 AromaticContact CD1-CE2 3.68Å; F129-F133 HydrophobicContact CD1-CE2 3.68Å; F129-F133 HydrophobicContact CE1-CE2 4.01Å; F129-F133 WeakPolarHBondContact O-CD2 3.43Å; F129-F133 PolarHBondContact O-N 3.28Å; F129-L140 HydrophobicContact CD1-CB 3.61Å; F129-L140 HydrophobicContact CD1-CD1 4.15Å; F129-L140 HydrophobicContact CE1-CB 4.21Å; F129-L140 HydrophobicContact CG-CB 4.36Å; F129-M144 HydrophobicContact CE1-CE 3.85Å; F129-M144 HydrophobicContact CE2-CE 3.59Å; F129-M144 HydrophobicContact CE2-SD 4.33Å; F129-M144 HydrophobicContact CZ-CE 3.2Å; F129-M144 HydrophobicContact CZ-SD 4.44Å; F129-L448 HydrophobicContact CE1-CB 4.28Å; F129-L448 HydrophobicContact CZ-CB 4.44Å; F129-F449 HydrophobicContact CE2-CD1 4.06Å; F129-F449 AromaticContact CE2-CE1 3.92Å; F129-F449 HydrophobicContact CE2-CE1 3.92Å; F129-F449 HydrophobicContact CZ-CD1 4.11Å; F129-F449 HydrophobicContact CZ-CE1 4.39Å; F129-L452 HydrophobicContact CD1-CD1 3.94Å; F129-L452 HydrophobicContact CD2-CD1 3.8Å; F129-L452 HydrophobicContact CE1-CB 4.08Å; F129-L452 HydrophobicContact CE1-CD1 3.84Å; F129-L452 HydrophobicContact CE2-CD1 3.71Å; F129-L452 HydrophobicContact CG-CD1 3.92Å; F129-L452 HydrophobicContact CZ-CB 4.17Å; F129-L452 HydrophobicContact CZ-CD1 3.71Å
130	C	95.9	Very high	95.8	Very high	4 Å²	4	23.5 Å²	23.5	3%	0.027	11%	0.111	C	C	.	.	H	α-helix	trans	-61.7	-32.9	173.6	-77.7	0	0	0	0	114	P126 V127 A128 F132 G134 F138 L549	P126-C130 PolarHBondContact O-N 2.85Å; V127-C130 WeakPolarHBondContact O-CB 3.2Å; V127-C130 PolarHBondContact O-N 3.48Å; V127-C130 VanDerWaalsContact O-N 3.16Å; A128-C130 VanDerWaalsContact C-N 3.31Å; A128-C130 PolarHBondContact O-N 3.24Å; C130-F132 PolarHBondContact O-N 2.92Å; C130-G134 CarbonylContact O-C 3.52Å; C130-G134 WeakPolarHBondContact O-CA 3.02Å; C130-G134 PolarHBondContact O-N 3.47Å; C130-F138 WeakPolarHBondContact SG-CA 3.34Å; C130-F138 WeakPolarHBondContact SG-CB 3.29Å; C130-L549 HydrophobicContact CB-CD1 4.36Å; C130-L549 HydrophobicContact CB-CD2 4.1Å
131	K	93.9	Very high	96	Very high	34 Å²	34	23.4 Å²	23.4	15%	0.148	11%	0.111	C	C	.	.	H	α-helix	trans	-66.1	-25.4	175.5	-73.4	-176.3	165.3	-178	0	112.6	T121 N123 V127 A128 F129 L549 H553 G554 C555 P557	T121-K131 HydrophobicContact CG2-CD 4.22Å; T121-K131 PolarHBondContact O-NZ 3.16Å; N123-K131 WeakPolarHBondContact OD1-CE 3.4Å; N123-K131 PolarHBondContact OD1-NZ 3.27Å; V127-K131 PolarHBondContact O-N 3.2Å; V127-K131 VanDerWaalsContact O-N 3.1Å; A128-K131 WeakPolarHBondContact O-CB 3.32Å; A128-K131 PolarHBondContact O-N 3.38Å; F129-K131 VanDerWaalsContact C-N 3.29Å; F129-K131 PolarHBondContact O-N 2.96Å; K131-L549 HydrophobicContact CG-CD2 4.05Å; K131-H553 PolarHBondContact NZ-O 3.48Å; K131-G554 PolarHBondContact NZ-O 3.05Å; K131-C555 PolarHBondContact NZ-O 2.91Å; K131-C555 VanDerWaalsContact NZ-O 3.16Å; K131-P557 HydrophobicContact CB-CG 4.2Å
132	F	96.2	Very high	96.2	Very high	11 Å²	11	23.7 Å²	23.7	5%	0.048	11%	0.113	C	C	.	.	H	α-helix	trans	-92	-45.2	178.1	-74.8	-96.8	0	0	0	113	L117 T121 A128 F129 C130 L452 Y456 Y461 L465 P557 Y558	L117-F132 HydrophobicContact CD1-CD2 4.12Å; L117-F132 HydrophobicContact CD1-CE2 3.35Å; L117-F132 HydrophobicContact CD1-CZ 3.93Å; T121-F132 HydrophobicContact CG2-CE2 4.04Å; A128-F132 VanDerWaalsContact O-CD2 3.3Å; A128-F132 WeakPolarHBondContact O-CD2 3.39Å; F129-F132 PolarHBondContact O-N 2.74Å; F129-F132 VanDerWaalsContact O-N 3.12Å; C130-F132 PolarHBondContact O-N 2.92Å; F132-L452 HydrophobicContact CB-CD1 4.27Å; F132-L452 HydrophobicContact CB-CG 4.17Å; F132-L452 HydrophobicContact CD1-CD2 3.77Å; F132-L452 HydrophobicContact CD1-CG 4.06Å; F132-L452 HydrophobicContact CD2-CD1 3.89Å; F132-L452 HydrophobicContact CD2-CD2 4.17Å; F132-L452 HydrophobicContact CD2-CG 4.21Å; F132-L452 HydrophobicContact CE1-CD2 3.73Å; F132-L452 HydrophobicContact CE1-CG 4.5Å; F132-L452 HydrophobicContact CE2-CD1 4.4Å; F132-L452 HydrophobicContact CE2-CD2 4.17Å; F132-L452 HydrophobicContact CG-CD1 4Å; F132-L452 HydrophobicContact CG-CD2 3.98Å; F132-L452 HydrophobicContact CG-CG 3.87Å; F132-L452 HydrophobicContact CZ-CD2 3.92Å; F132-Y456 AromaticContact CD1-CD2 3.75Å; F132-Y456 HydrophobicContact CD1-CD2 3.75Å; F132-Y456 AromaticContact CD1-CG 3.95Å; F132-Y456 HydrophobicContact CD1-CG 3.95Å; F132-Y456 HydrophobicContact CE1-CD1 4.26Å; F132-Y456 AromaticContact CE1-CD2 3.69Å; F132-Y456 HydrophobicContact CE1-CD2 3.69Å; F132-Y456 HydrophobicContact CE1-CE2 4.22Å; F132-Y456 AromaticContact CE1-CG 3.71Å; F132-Y456 HydrophobicContact CE1-CG 3.71Å; F132-Y461 HydrophobicContact CE1-CD2 4.34Å; F132-Y461 HydrophobicContact CE1-CE2 4.25Å; F132-Y461 HydrophobicContact CZ-CE2 4.17Å; F132-L465 HydrophobicContact CE1-CD2 4.4Å; F132-L465 HydrophobicContact CZ-CD2 3.64Å; F132-P557 HydrophobicContact CD1-CB 4.16Å; F132-P557 HydrophobicContact CD1-CG 4.11Å; F132-P557 HydrophobicContact CD2-CG 3.98Å; F132-P557 HydrophobicContact CE1-CB 3.58Å; F132-P557 HydrophobicContact CE1-CG 3.97Å; F132-P557 HydrophobicContact CE2-CB 4.02Å; F132-P557 HydrophobicContact CE2-CG 3.82Å; F132-P557 HydrophobicContact CG-CG 4.14Å; F132-P557 HydrophobicContact CZ-CB 3.52Å; F132-P557 HydrophobicContact CZ-CG 3.83Å; F132-Y558 PolarHBondContact O-OH 2.93Å
133	F	96.6	Very high	96.4	Very high	41 Å²	41	23 Å²	23	18%	0.18	11%	0.111	C	C	.	.	H	α-helix	trans	-103.3	-13.9	-171.1	-65.3	-74.9	0	0	0	113.7	F129 F137 L140 L451 L452 V455	F129-F133 HydrophobicContact CB-CD2 4.49Å; F129-F133 AromaticContact CD1-CD2 3.91Å; F129-F133 HydrophobicContact CD1-CD2 3.91Å; F129-F133 AromaticContact CD1-CE2 3.68Å; F129-F133 HydrophobicContact CD1-CE2 3.68Å; F129-F133 HydrophobicContact CE1-CE2 4.01Å; F129-F133 WeakPolarHBondContact O-CD2 3.43Å; F129-F133 PolarHBondContact O-N 3.28Å; F133-F137 HydrophobicContact CB-CB 3.55Å; F133-F137 HydrophobicContact CB-CD2 3.84Å; F133-F137 HydrophobicContact CB-CG 3.83Å; F133-F137 HydrophobicContact CG-CB 4.42Å; F133-F137 WeakPolarHBondContact O-CD2 3.08Å; F133-L140 HydrophobicContact CD2-CD1 3.82Å; F133-L140 HydrophobicContact CE2-CD1 4Å; F133-L140 HydrophobicContact CG-CD1 4.12Å; F133-L140 HydrophobicContact CZ-CD1 4.43Å; F133-L451 HydrophobicContact CZ-CG 4.42Å; F133-L452 HydrophobicContact CE2-CB 3.85Å; F133-L452 HydrophobicContact CE2-CD1 4.17Å; F133-L452 HydrophobicContact CE2-CG 3.98Å; F133-L452 HydrophobicContact CZ-CB 4.1Å; F133-V455 HydrophobicContact CD1-CG1 4.29Å; F133-V455 HydrophobicContact CE1-CB 3.81Å; F133-V455 HydrophobicContact CE1-CG1 3.77Å; F133-V455 HydrophobicContact CE1-CG2 3.93Å; F133-V455 HydrophobicContact CZ-CB 4.32Å; F133-V455 HydrophobicContact CZ-CG2 4.5Å
134	G	94.5	Very high	96.5	Very high	31 Å²	31	23 Å²	23	32%	0.32	11%	0.111	S	C	.	.			trans	89.9	173	-172.1	0	0	0	0	0	113.7	C130 K136 F137	C130-G134 CarbonylContact O-C 3.52Å; C130-G134 WeakPolarHBondContact O-CA 3.02Å; C130-G134 PolarHBondContact O-N 3.47Å; G134-K136 VanDerWaalsContact C-N 3.27Å; G134-K136 PolarHBondContact O-N 3.19Å; G134-F137 PolarHBondContact O-N 2.89Å; G134-F137 VanDerWaalsContact O-N 3.16Å
135	Q	93.4	Very high	96.6	Very high	56 Å²	56	24.1 Å²	24.1	26%	0.262	12%	0.117	S	C	.	.	G	3₁₀ helix	trans	-62.6	-29.4	-169.9	-67	-173.4	51.9	0	0	114.2	F137 F138 N536 Y540 L545 L549	Q135-F137 PolarHBondContact O-N 3.49Å; Q135-F137 VanDerWaalsContact O-N 3.15Å; Q135-F138 PolarHBondContact O-N 3.3Å; Q135-N536 PolarHBondContact O-OD1 3.47Å; Q135-Y540 HydrophobicContact CB-CD2 3.84Å; Q135-Y540 HydrophobicContact CB-CE2 4.03Å; Q135-L545 HydrophobicContact CB-CD2 3.61Å; Q135-L545 HydrophobicContact CB-CG 4.15Å; Q135-L545 HydrophobicContact CG-CD2 3.98Å; Q135-L545 HydrophobicContact CG-CG 3.96Å; Q135-L545 WeakPolarHBondContact O-CD2 3.13Å; Q135-L549 HydrophobicContact CG-CD1 3.46Å; Q135-L549 VanDerWaalsContact CG-CD1 3.46Å
136	K	94.1	Very high	96.6	Very high	130 Å²	130	25.3 Å²	25.3	57%	0.565	13%	0.125	S	C	*	.	G	3₁₀ helix	trans	-68	-12.4	-179.6	-64	-177.5	-178.2	177.7	0	113.4	G134 N536 Y540	G134-K136 VanDerWaalsContact C-N 3.27Å; G134-K136 PolarHBondContact O-N 3.19Å; K136-N536 PolarHBondContact O-ND2 3.37Å; K136-Y540 HydrophobicContact CG-CE2 4.16Å
137	F	96.1	Very high	96.6	Very high	91 Å²	91	25.3 Å²	25.3	40%	0.399	13%	0.125	S	C	.	.	G	3₁₀ helix	trans	-114.1	18.6	-174.2	-63.8	-84.4	0	0	0	113.5	F133 G134 Q135 W139 L140	F133-F137 HydrophobicContact CB-CB 3.55Å; F133-F137 HydrophobicContact CB-CD2 3.84Å; F133-F137 HydrophobicContact CB-CG 3.83Å; F133-F137 HydrophobicContact CG-CB 4.42Å; F133-F137 WeakPolarHBondContact O-CD2 3.08Å; G134-F137 PolarHBondContact O-N 2.89Å; G134-F137 VanDerWaalsContact O-N 3.16Å; Q135-F137 PolarHBondContact O-N 3.49Å; Q135-F137 VanDerWaalsContact O-N 3.15Å; F137-W139 AromaticContact CD1-NE1 3.93Å; F137-W139 PolarHBondContact O-N 3.5Å; F137-W139 VanDerWaalsContact O-N 3.14Å; F137-L140 HydrophobicContact CB-CD1 3.87Å; F137-L140 HydrophobicContact CB-CG 4.25Å; F137-L140 HydrophobicContact CD1-CD1 4.14Å; F137-L140 HydrophobicContact CG-CD1 4.39Å; F137-L140 WeakPolarHBondContact O-CB 3.29Å; F137-L140 PolarHBondContact O-N 2.99Å
138	F	96.6	Very high	96.7	Very high	7 Å²	7	25.3 Å²	25.3	3%	0.031	13%	0.125	C	C	.	.	H	α-helix	trans	-52.8	-34.9	173.6	-179.2	-93.3	0	0	0	112.5	P126 V127 C130 Q135 L140 G141 A142 L402 N536 L539 L545	P126-F138 HydrophobicContact CB-CD1 4.35Å; P126-F138 HydrophobicContact CB-CD2 3.71Å; P126-F138 HydrophobicContact CB-CE1 3.98Å; P126-F138 HydrophobicContact CB-CE2 3.3Å; P126-F138 HydrophobicContact CB-CG 4.22Å; P126-F138 HydrophobicContact CB-CZ 3.44Å; P126-F138 VanDerWaalsContact CB-CZ 3.44Å; P126-F138 HydrophobicContact CG-CE2 4.44Å; P126-F138 HydrophobicContact CG-CZ 4.21Å; V127-F138 HydrophobicContact CG2-CE2 4.15Å; C130-F138 WeakPolarHBondContact SG-CA 3.34Å; C130-F138 WeakPolarHBondContact SG-CB 3.29Å; Q135-F138 PolarHBondContact O-N 3.3Å; F138-L140 PolarHBondContact O-N 3.29Å; F138-L140 VanDerWaalsContact O-N 3.12Å; F138-G141 PolarHBondContact O-N 3.48Å; F138-A142 HydrophobicContact CD1-CB 4.03Å; F138-A142 HydrophobicContact CE1-CB 3.89Å; F138-A142 PolarHBondContact O-N 3.25Å; F138-L402 HydrophobicContact CZ-CD1 4.33Å; F138-L402 HydrophobicContact CZ-CD2 4.33Å; F138-N536 VanDerWaalsContact CB-OD1 3.26Å; F138-N536 WeakPolarHBondContact CB-OD1 3.5Å; F138-L539 HydrophobicContact CD1-CD1 4.06Å; F138-L539 HydrophobicContact CE1-CD1 3.7Å; F138-L539 HydrophobicContact CZ-CD1 4.13Å; F138-L545 HydrophobicContact CB-CD2 3.85Å; F138-L545 HydrophobicContact CD2-CD1 3.62Å; F138-L545 HydrophobicContact CD2-CD2 4.17Å; F138-L545 HydrophobicContact CE2-CD1 4.07Å; F138-L545 HydrophobicContact CG-CD1 4.48Å; F138-L545 HydrophobicContact CG-CD2 4.27Å
139	W	97.5	Very high	96.7	Very high	54 Å²	54	28 Å²	28	21%	0.205	14%	0.137	C	C	.	.	H	α-helix	trans	-57.1	-25.4	179.2	71.2	-93.7	0	0	0	113.6	F137 A142 W143 L529 L532 F533 N536	F137-W139 AromaticContact CD1-NE1 3.93Å; F137-W139 PolarHBondContact O-N 3.5Å; F137-W139 VanDerWaalsContact O-N 3.14Å; W139-A142 PolarHBondContact O-N 3.1Å; W139-W143 PolarHBondContact O-N 2.88Å; W139-L529 HydrophobicContact CE3-CD2 4.31Å; W139-L529 HydrophobicContact CZ3-CD2 4.07Å; W139-L532 HydrophobicContact CB-CB 4.23Å; W139-F533 HydrophobicContact CD2-CD1 4.23Å; W139-F533 AromaticContact CD2-CE1 3.59Å; W139-F533 HydrophobicContact CD2-CE1 3.59Å; W139-F533 HydrophobicContact CD2-CZ 4.47Å; W139-F533 AromaticContact CE2-CE1 3.59Å; W139-F533 AromaticContact CE3-CE1 3.99Å; W139-F533 HydrophobicContact CE3-CE1 3.99Å; W139-F533 HydrophobicContact CE3-CZ 4.49Å; W139-F533 HydrophobicContact CG-CD1 4.09Å; W139-F533 AromaticContact CG-CE1 3.93Å; W139-F533 HydrophobicContact CG-CE1 3.93Å; W139-F533 HydrophobicContact CH2-CE1 4.31Å; W139-F533 HydrophobicContact CH2-CZ 4.41Å; W139-F533 AromaticContact CZ2-CE1 3.97Å; W139-F533 HydrophobicContact CZ2-CE1 3.97Å; W139-F533 HydrophobicContact CZ2-CZ 4.41Å; W139-F533 HydrophobicContact CZ3-CE1 4.33Å; W139-F533 HydrophobicContact CZ3-CZ 4.46Å; W139-F533 AromaticContact NE1-CE1 3.87Å; W139-N536 HydrophobicContact CB-CB 4.17Å
140	L	98	Very high	96.7	Very high	8 Å²	8	30.2 Å²	30.2	4%	0.042	15%	0.146	C	C	.	.	H	α-helix	trans	-64	-48.3	178.5	-66.5	177.2	0	0	0	112	F129 F133 F137 F138 W143 L448	F129-L140 HydrophobicContact CD1-CB 3.61Å; F129-L140 HydrophobicContact CD1-CD1 4.15Å; F129-L140 HydrophobicContact CE1-CB 4.21Å; F129-L140 HydrophobicContact CG-CB 4.36Å; F133-L140 HydrophobicContact CD2-CD1 3.82Å; F133-L140 HydrophobicContact CE2-CD1 4Å; F133-L140 HydrophobicContact CG-CD1 4.12Å; F133-L140 HydrophobicContact CZ-CD1 4.43Å; F137-L140 HydrophobicContact CB-CD1 3.87Å; F137-L140 HydrophobicContact CB-CG 4.25Å; F137-L140 HydrophobicContact CD1-CD1 4.14Å; F137-L140 HydrophobicContact CG-CD1 4.39Å; F137-L140 WeakPolarHBondContact O-CB 3.29Å; F137-L140 PolarHBondContact O-N 2.99Å; F138-L140 PolarHBondContact O-N 3.29Å; F138-L140 VanDerWaalsContact O-N 3.12Å; L140-W143 WeakPolarHBondContact O-CB 3.43Å; L140-L448 HydrophobicContact CD2-CD1 4.45Å; L140-L448 HydrophobicContact CD2-CD2 3.86Å; L140-L448 WeakPolarHBondContact O-CD1 3.31Å
141	G	97.8	Very high	96.7	Very high	0 Å²	0	30.1 Å²	30.1	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-77.4	-29.2	174.7	0	0	0	0	0	111.9	F138 W143 M144 V145	F138-G141 PolarHBondContact O-N 3.48Å; G141-W143 VanDerWaalsContact C-N 3.27Å; G141-W143 PolarHBondContact O-N 3.5Å; G141-M144 WeakPolarHBondContact O-CB 3.49Å; G141-M144 PolarHBondContact O-N 3.05Å; G141-M144 VanDerWaalsContact O-N 3.14Å; G141-V145 PolarHBondContact O-N 3.33Å
142	A	98.1	Very high	96.8	Very high	6 Å²	6	28.7 Å²	28.7	5%	0.05	14%	0.14	C	C	.	.	H	α-helix	trans	-68.3	-25.8	175.9	0	0	0	0	0	113	P126 F138 W139 M144 V145 T146 L532	P126-A142 HydrophobicContact CG-CB 4.34Å; F138-A142 HydrophobicContact CD1-CB 4.03Å; F138-A142 HydrophobicContact CE1-CB 3.89Å; F138-A142 PolarHBondContact O-N 3.25Å; W139-A142 PolarHBondContact O-N 3.1Å; A142-M144 VanDerWaalsContact C-N 3.33Å; A142-V145 PolarHBondContact O-N 2.89Å; A142-T146 WeakPolarHBondContact O-CB 3.33Å; A142-T146 PolarHBondContact O-N 3.3Å; A142-T146 PolarHBondContact O-OG1 3.41Å; A142-L532 HydrophobicContact CB-CD2 3.68Å
143	W	98.3	Very high	96.9	Very high	5 Å²	5	28.3 Å²	28.3	2%	0.019	14%	0.139	C	C	.	.	H	α-helix	trans	-54.5	-50.3	166.5	168.7	-93.2	0	0	0	110.9	W139 L140 G141 V145 T146 V147 G441 I444 S445 L448 W525 L529 L532	W139-W143 PolarHBondContact O-N 2.88Å; L140-W143 WeakPolarHBondContact O-CB 3.43Å; G141-W143 VanDerWaalsContact C-N 3.27Å; G141-W143 PolarHBondContact O-N 3.5Å; W143-V145 VanDerWaalsContact C-N 3.33Å; W143-V145 PolarHBondContact O-N 2.96Å; W143-T146 WeakPolarHBondContact O-CA 3.37Å; W143-T146 WeakPolarHBondContact O-CB 3.44Å; W143-T146 PolarHBondContact O-N 3.48Å; W143-V147 HydrophobicContact CD2-CG2 4.11Å; W143-V147 HydrophobicContact CG-CG2 4.42Å; W143-V147 HydrophobicContact CZ2-CG2 3.81Å; W143-V147 WeakPolarHBondContact O-CG2 3.12Å; W143-V147 PolarHBondContact O-N 3.3Å; W143-G441 PolarHBondContact NE1-O 3.09Å; W143-I444 HydrophobicContact CH2-CD1 4.24Å; W143-I444 HydrophobicContact CZ2-CB 4.04Å; W143-I444 HydrophobicContact CZ2-CD1 3.71Å; W143-I444 HydrophobicContact CZ2-CG1 4.43Å; W143-I444 HydrophobicContact CZ2-CG2 4.09Å; W143-S445 PolarHBondContact NE1-OG 3.43Å; W143-L448 HydrophobicContact CB-CD1 4.38Å; W143-L448 HydrophobicContact CG-CD1 4.25Å; W143-W525 HydrophobicContact CH2-CB 4.12Å; W143-W525 AromaticContact CH2-CD1 3.89Å; W143-W525 HydrophobicContact CH2-CD2 4.19Å; W143-W525 AromaticContact CH2-CG 3.8Å; W143-W525 HydrophobicContact CH2-CG 3.8Å; W143-W525 HydrophobicContact CZ3-CB 4.48Å; W143-L529 HydrophobicContact CE3-CD2 3.71Å; W143-L529 HydrophobicContact CE3-CG 4.18Å; W143-L529 HydrophobicContact CZ3-CD1 4.5Å; W143-L529 HydrophobicContact CZ3-CD2 3.95Å; W143-L529 HydrophobicContact CZ3-CG 3.9Å; W143-L532 HydrophobicContact CB-CD1 4.11Å; W143-L532 HydrophobicContact CE3-CD1 4.25Å
144	M	98	Very high	96.8	Very high	0 Å²	0	26.7 Å²	26.7	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-63.8	-41.5	-178.7	-49	-174.7	-163.3	0	0	111.5	V125 F129 G141 A142 T146 V147 V148 L448 F449	V125-M144 HydrophobicContact CG1-CB 4.43Å; V125-M144 HydrophobicContact CG1-CE 4.42Å; V125-M144 HydrophobicContact CG1-CG 4.42Å; V125-M144 HydrophobicContact CG1-SD 3.56Å; V125-M144 VanDerWaalsContact CG1-SD 3.56Å; F129-M144 HydrophobicContact CE1-CE 3.85Å; F129-M144 HydrophobicContact CE2-CE 3.59Å; F129-M144 HydrophobicContact CE2-SD 4.33Å; F129-M144 HydrophobicContact CZ-CE 3.2Å; F129-M144 HydrophobicContact CZ-SD 4.44Å; G141-M144 WeakPolarHBondContact O-CB 3.49Å; G141-M144 PolarHBondContact O-N 3.05Å; G141-M144 VanDerWaalsContact O-N 3.14Å; A142-M144 VanDerWaalsContact C-N 3.33Å; M144-T146 VanDerWaalsContact C-N 3.27Å; M144-T146 PolarHBondContact O-N 3.11Å; M144-V147 PolarHBondContact O-N 3.16Å; M144-V148 WeakPolarHBondContact O-CB 3.35Å; M144-V148 WeakPolarHBondContact O-CG2 3.44Å; M144-V148 PolarHBondContact O-N 3.33Å; M144-L448 HydrophobicContact CE-CB 3.41Å; M144-L448 VanDerWaalsContact CE-CB 3.41Å; M144-L448 HydrophobicContact CE-CD1 4.04Å; M144-L448 HydrophobicContact CE-CG 4.38Å; M144-F449 HydrophobicContact CE-CD2 4.21Å; M144-F449 HydrophobicContact CE-CE2 4.16Å; M144-F449 HydrophobicContact CE-CG 4.48Å; M144-F449 HydrophobicContact CE-CZ 4.37Å; M144-F449 HydrophobicContact SD-CD2 3.94Å; M144-F449 HydrophobicContact SD-CE1 4.24Å; M144-F449 HydrophobicContact SD-CE2 3.33Å; M144-F449 WeakPolarHBondContact SD-CE2 3.4Å; M144-F449 HydrophobicContact SD-CZ 3.5Å; M144-F449 VanDerWaalsContact SD-CZ 3.5Å
145	V	98.3	Very high	96.9	Very high	24 Å²	24	25.8 Å²	25.8	15%	0.145	12%	0.118	C	C	.	.	H	α-helix	trans	-60.3	-39.3	173.7	179.7	0	0	0	0	111	P126 G141 A142 W143 F149 I394 A398	P126-V145 HydrophobicContact CG-CG2 3.59Å; G141-V145 PolarHBondContact O-N 3.33Å; A142-V145 PolarHBondContact O-N 2.89Å; W143-V145 VanDerWaalsContact C-N 3.33Å; W143-V145 PolarHBondContact O-N 2.96Å; V145-F149 WeakPolarHBondContact O-CB 3.45Å; V145-F149 PolarHBondContact O-N 3.3Å; V145-I394 HydrophobicContact CG2-CG2 3.99Å; V145-A398 HydrophobicContact CG1-CB 4.38Å; V145-A398 HydrophobicContact CG2-CB 4.11Å
146	T	98.3	Very high	97	Very high	27 Å²	27	23.1 Å²	23.1	17%	0.166	11%	0.106	C	C	.	.	H	α-helix	trans	-68	-48.2	179.1	-58.2	0	0	0	0	111.7	A142 W143 M144 V148 F149 F150 A528	A142-T146 WeakPolarHBondContact O-CB 3.33Å; A142-T146 PolarHBondContact O-N 3.3Å; A142-T146 PolarHBondContact O-OG1 3.41Å; W143-T146 WeakPolarHBondContact O-CA 3.37Å; W143-T146 WeakPolarHBondContact O-CB 3.44Å; W143-T146 PolarHBondContact O-N 3.48Å; M144-T146 VanDerWaalsContact C-N 3.27Å; M144-T146 PolarHBondContact O-N 3.11Å; T146-V148 VanDerWaalsContact C-N 3.33Å; T146-V148 PolarHBondContact O-N 3.16Å; T146-F149 WeakPolarHBondContact O-CB 3.31Å; T146-F149 PolarHBondContact O-N 3.17Å; T146-F150 HydrophobicContact CG2-CD2 3.9Å; T146-F150 HydrophobicContact CG2-CE2 3.67Å; T146-F150 VanDerWaalsContact O-CD2 3.27Å; T146-F150 WeakPolarHBondContact O-CD2 3.26Å; T146-F150 PolarHBondContact O-N 3.15Å; T146-A528 HydrophobicContact CG2-CB 4.36Å
147	V	97.6	Very high	97.1	Very high	0 Å²	0	16.9 Å²	16.9	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-56.9	-49.1	177.3	174.3	0	0	0	0	110.3	W143 M144 F149 F150 L151 W438 L442	W143-V147 HydrophobicContact CD2-CG2 4.11Å; W143-V147 HydrophobicContact CG-CG2 4.42Å; W143-V147 HydrophobicContact CZ2-CG2 3.81Å; W143-V147 WeakPolarHBondContact O-CG2 3.12Å; W143-V147 PolarHBondContact O-N 3.3Å; M144-V147 PolarHBondContact O-N 3.16Å; V147-F149 VanDerWaalsContact C-N 3.32Å; V147-F149 PolarHBondContact O-N 3.44Å; V147-F150 PolarHBondContact O-N 3.41Å; V147-L151 PolarHBondContact O-N 2.92Å; V147-W438 HydrophobicContact CB-CE3 4.26Å; V147-W438 HydrophobicContact CG1-CB 4.29Å; V147-W438 HydrophobicContact CG1-CE3 4.38Å; V147-W438 VanDerWaalsContact CG1-O 3.3Å; V147-W438 WeakPolarHBondContact CG1-O 3.34Å; V147-W438 HydrophobicContact CG2-CE3 3.96Å; V147-W438 HydrophobicContact CG2-CZ3 4.23Å; V147-L442 HydrophobicContact CG1-CD2 3.57Å; V147-L442 HydrophobicContact CG1-CG 3.82Å
148	V	97.1	Very high	97	Very high	2 Å²	2	12.9 Å²	12.9	1%	0.012	6%	0.062	C	C	.	.	H	α-helix	trans	-71.9	-28	-179.2	176.6	0	0	0	0	112.3	M144 T146 L151 S152 M281 I391 I394 L442	M144-V148 WeakPolarHBondContact O-CB 3.35Å; M144-V148 WeakPolarHBondContact O-CG2 3.44Å; M144-V148 PolarHBondContact O-N 3.33Å; T146-V148 VanDerWaalsContact C-N 3.33Å; T146-V148 PolarHBondContact O-N 3.16Å; V148-L151 VanDerWaalsContact O-CB 3.31Å; V148-L151 WeakPolarHBondContact O-CB 3.38Å; V148-L151 PolarHBondContact O-N 3.37Å; V148-S152 WeakPolarHBondContact O-CB 3.26Å; V148-S152 PolarHBondContact O-N 3.02Å; V148-M281 HydrophobicContact CG2-CB 3.96Å; V148-M281 HydrophobicContact CG2-CG 4.4Å; V148-M281 WeakPolarHBondContact CG2-O 3.45Å; V148-I391 HydrophobicContact CG1-CB 4.09Å; V148-I391 HydrophobicContact CG1-CG1 4.17Å; V148-I391 HydrophobicContact CG1-CG2 3.62Å; V148-I394 HydrophobicContact CB-CD1 4.41Å; V148-I394 HydrophobicContact CG1-CD1 3.7Å; V148-I394 HydrophobicContact CG2-CD1 4.44Å; V148-L442 HydrophobicContact CG2-CD2 4.17Å
149	F	97.9	Very high	97	Very high	57 Å²	57	12.6 Å²	12.6	25%	0.25	6%	0.06	C	C	.	.	H	α-helix	trans	-62.8	-48.4	170.8	170.1	-104.2	0	0	0	111.4	V145 T146 V147 L151 S152 C153 A416 I420	V145-F149 WeakPolarHBondContact O-CB 3.45Å; V145-F149 PolarHBondContact O-N 3.3Å; T146-F149 WeakPolarHBondContact O-CB 3.31Å; T146-F149 PolarHBondContact O-N 3.17Å; V147-F149 VanDerWaalsContact C-N 3.32Å; V147-F149 PolarHBondContact O-N 3.44Å; F149-L151 VanDerWaalsContact C-N 3.29Å; F149-L151 PolarHBondContact O-N 3.06Å; F149-S152 CarbonylContact O-C 3.6Å; F149-S152 WeakPolarHBondContact O-CA 3.24Å; F149-S152 VanDerWaalsContact O-CB 3.27Å; F149-S152 WeakPolarHBondContact O-CB 3.47Å; F149-S152 PolarHBondContact O-N 3.26Å; F149-S152 PolarHBondContact O-OG 2.94Å; F149-C153 PolarHBondContact O-N 3.4Å; F149-C153 VanDerWaalsContact O-N 3.13Å; F149-C153 PolarHBondContact O-SG 3.36Å; F149-A416 HydrophobicContact CE2-CB 3.87Å; F149-A416 HydrophobicContact CZ-CB 3.74Å; F149-I420 HydrophobicContact CE1-CD1 3.84Å; F149-I420 HydrophobicContact CZ-CD1 3.78Å
150	F	97.5	Very high	96.9	Very high	47 Å²	47	10 Å²	10	21%	0.206	5%	0.051	C	C	.	.	H	α-helix	trans	-66.7	-32.9	176.2	-75	-73	0	0	0	112.6	T146 V147 S152 C153 Y154 I420 W438	T146-F150 HydrophobicContact CG2-CD2 3.9Å; T146-F150 HydrophobicContact CG2-CE2 3.67Å; T146-F150 VanDerWaalsContact O-CD2 3.27Å; T146-F150 WeakPolarHBondContact O-CD2 3.26Å; T146-F150 PolarHBondContact O-N 3.15Å; V147-F150 PolarHBondContact O-N 3.41Å; F150-S152 VanDerWaalsContact C-N 3.26Å; F150-S152 PolarHBondContact O-N 3.46Å; F150-C153 WeakPolarHBondContact O-CB 3.37Å; F150-C153 PolarHBondContact O-N 2.94Å; F150-Y154 WeakPolarHBondContact O-CD1 3.45Å; F150-Y154 PolarHBondContact O-N 2.91Å; F150-I420 HydrophobicContact CD1-CG2 4.4Å; F150-I420 HydrophobicContact CE1-CG2 4.23Å; F150-W438 HydrophobicContact CB-CD2 3.64Å; F150-W438 VanDerWaalsContact CB-CE2 3.47Å; F150-W438 HydrophobicContact CB-CE3 4.48Å; F150-W438 HydrophobicContact CB-CG 3.58Å; F150-W438 HydrophobicContact CB-CZ2 4.19Å; F150-W438 VanDerWaalsContact CB-NE1 3.27Å; F150-W438 HydrophobicContact CD1-CZ2 4.17Å; F150-W438 AromaticContact CD1-NE1 3.87Å; F150-W438 AromaticContact CD2-CD2 3.91Å; F150-W438 HydrophobicContact CD2-CD2 3.91Å; F150-W438 AromaticContact CD2-CE2 3.38Å; F150-W438 HydrophobicContact CD2-CE3 4.18Å; F150-W438 AromaticContact CD2-CH2 3.48Å; F150-W438 HydrophobicContact CD2-CH2 3.48Å; F150-W438 VanDerWaalsContact CD2-CH2 3.48Å; F150-W438 AromaticContact CD2-CZ2 3.15Å; F150-W438 HydrophobicContact CD2-CZ2 3.15Å; F150-W438 AromaticContact CD2-CZ3 3.98Å; F150-W438 HydrophobicContact CD2-CZ3 3.98Å; F150-W438 AromaticContact CD2-NE1 3.96Å; F150-W438 HydrophobicContact CE1-CZ2 4.36Å; F150-W438 AromaticContact CE2-CH2 3.59Å; F150-W438 HydrophobicContact CE2-CH2 3.59Å; F150-W438 AromaticContact CE2-CZ2 3.38Å; F150-W438 HydrophobicContact CE2-CZ2 3.38Å; F150-W438 HydrophobicContact CE2-CZ3 4.43Å; F150-W438 AromaticContact CG-CD2 3.99Å; F150-W438 HydrophobicContact CG-CD2 3.99Å; F150-W438 AromaticContact CG-CE2 3.38Å; F150-W438 HydrophobicContact CG-CG 4.4Å; F150-W438 HydrophobicContact CG-CH2 4.34Å; F150-W438 AromaticContact CG-CZ2 3.6Å; F150-W438 HydrophobicContact CG-CZ2 3.6Å; F150-W438 AromaticContact CG-NE1 3.45Å; F150-W438 HydrophobicContact CZ-CZ2 4Å
151	L	95.1	Very high	96.8	Very high	2 Å²	2	9.9 Å²	9.9	1%	0.01	5%	0.049	C	C	.	.	H	α-helix	trans	-55	-45.8	166.7	-147.9	86.8	0	0	0	110.8	V147 V148 F149 C153 Y154 Y155 M281 I391 L442	V147-L151 PolarHBondContact O-N 2.92Å; V148-L151 VanDerWaalsContact O-CB 3.31Å; V148-L151 WeakPolarHBondContact O-CB 3.38Å; V148-L151 PolarHBondContact O-N 3.37Å; F149-L151 VanDerWaalsContact C-N 3.29Å; F149-L151 PolarHBondContact O-N 3.06Å; L151-C153 PolarHBondContact O-N 3.34Å; L151-Y154 HydrophobicContact CB-CE1 4.35Å; L151-Y154 HydrophobicContact CD1-CE1 3.71Å; L151-Y154 WeakPolarHBondContact CD1-OH 3.36Å; L151-Y154 HydrophobicContact CG-CE1 4.07Å; L151-Y154 PolarHBondContact O-N 3.21Å; L151-Y155 WeakPolarHBondContact O-CB 3.46Å; L151-Y155 PolarHBondContact O-N 3.39Å; L151-M281 HydrophobicContact CD2-CE 4.21Å; L151-M281 HydrophobicContact CD2-SD 4.27Å; L151-I391 HydrophobicContact CD2-CD1 3.97Å; L151-L442 HydrophobicContact CD1-CD1 4.48Å
152	S	96.9	Very high	96.8	Very high	4 Å²	4	9.9 Å²	9.9	3%	0.028	5%	0.049	C	C	.	.	H	α-helix	trans	-65.8	-14.2	176.4	88.4	0	0	0	0	113.9	V148 F149 F150 P156 I391 S417	V148-S152 WeakPolarHBondContact O-CB 3.26Å; V148-S152 PolarHBondContact O-N 3.02Å; F149-S152 CarbonylContact O-C 3.6Å; F149-S152 WeakPolarHBondContact O-CA 3.24Å; F149-S152 VanDerWaalsContact O-CB 3.27Å; F149-S152 WeakPolarHBondContact O-CB 3.47Å; F149-S152 PolarHBondContact O-N 3.26Å; F149-S152 PolarHBondContact O-OG 2.94Å; F150-S152 VanDerWaalsContact C-N 3.26Å; F150-S152 PolarHBondContact O-N 3.46Å; S152-P156 WeakPolarHBondContact O-CD 3.36Å; S152-P156 WeakPolarHBondContact O-CG 3.42Å; S152-I391 VanDerWaalsContact CB-CG2 3.43Å; S152-S417 WeakPolarHBondContact O-CB 3.27Å; S152-S417 PolarHBondContact O-OG 2.95Å
153	C	97.6	Very high	96.7	Very high	3 Å²	3	10.5 Å²	10.5	2%	0.02	5%	0.052	C	C	.	.	H	α-helix	trans	-83.4	-45.4	177.1	-61.3	0	0	0	0	112	F149 F150 L151 I420 G421	F149-C153 PolarHBondContact O-N 3.4Å; F149-C153 VanDerWaalsContact O-N 3.13Å; F149-C153 PolarHBondContact O-SG 3.36Å; F150-C153 WeakPolarHBondContact O-CB 3.37Å; F150-C153 PolarHBondContact O-N 2.94Å; L151-C153 PolarHBondContact O-N 3.34Å; C153-I420 HydrophobicContact CB-CB 4.38Å; C153-I420 HydrophobicContact CB-CG2 4.14Å; C153-G421 WeakPolarHBondContact O-CA 3.21Å
154	Y	95	Very high	96.7	Very high	6 Å²	6	11.5 Å²	11.5	2%	0.024	6%	0.056	C	C	.	.	H	α-helix	trans	-90.2	-29	-178.8	78.2	-98.8	0	0	0	113.2	F150 L151 P156 V157 Q434 D435	F150-Y154 WeakPolarHBondContact O-CD1 3.45Å; F150-Y154 PolarHBondContact O-N 2.91Å; L151-Y154 HydrophobicContact CB-CE1 4.35Å; L151-Y154 HydrophobicContact CD1-CE1 3.71Å; L151-Y154 WeakPolarHBondContact CD1-OH 3.36Å; L151-Y154 HydrophobicContact CG-CE1 4.07Å; L151-Y154 PolarHBondContact O-N 3.21Å; Y154-P156 VanDerWaalsContact C-CD 3.45Å; Y154-V157 WeakPolarHBondContact O-CB 3.23Å; Y154-V157 PolarHBondContact O-N 2.91Å; Y154-Q434 HydrophobicContact CD1-CB 4.03Å; Y154-Q434 HydrophobicContact CG-CB 4.48Å; Y154-D435 HydrophobicContact CE2-CB 3.91Å; Y154-D435 WeakPolarHBondContact CE2-OD1 3.48Å; Y154-D435 VanDerWaalsContact CZ-OD1 3.27Å; Y154-D435 PolarHBondContact OH-OD1 3.12Å
155	Y	95.3	Very high	96.6	Very high	12 Å²	12	11.7 Å²	11.7	5%	0.047	6%	0.056	C	C	.	.	H	α-helix	trans	-57.8	-40.1	-179.2	-171.8	-101.3	0	0	0	114.3	T73 L151 V157 V158 L159 G384 S387 L388	T73-Y155 PolarHBondContact N-OH 3.2Å; T73-Y155 VanDerWaalsContact OG1-CE2 3.3Å; T73-Y155 WeakPolarHBondContact OG1-CE2 3.2Å; T73-Y155 PolarHBondContact OG1-OH 2.99Å; L151-Y155 WeakPolarHBondContact O-CB 3.46Å; L151-Y155 PolarHBondContact O-N 3.39Å; Y155-V157 PolarHBondContact O-N 3.49Å; Y155-V158 PolarHBondContact O-N 3.41Å; Y155-V158 VanDerWaalsContact O-N 3.16Å; Y155-L159 PolarHBondContact O-N 2.89Å; Y155-G384 WeakPolarHBondContact CE1-O 3.3Å; Y155-G384 WeakPolarHBondContact OH-CA 3.34Å; Y155-S387 WeakPolarHBondContact CE1-OG 3.2Å; Y155-S387 VanDerWaalsContact CZ-OG 3.24Å; Y155-S387 PolarHBondContact OH-OG 3.45Å; Y155-L388 HydrophobicContact CD1-CB 4.08Å; Y155-L388 HydrophobicContact CD1-CD1 4.15Å; Y155-L388 HydrophobicContact CE1-CB 4.14Å
156	P	97.1	Very high	96.6	Very high	0 Å²	0	13.6 Å²	13.6	0%	0	6%	0.063	C	C	.	.	H	α-helix	trans	-62.4	-22.6	175	-18.7	29.7	0	0	0	113.7	S152 Y154 L159 G160 Q199 A202 V203 L388	S152-P156 WeakPolarHBondContact O-CD 3.36Å; S152-P156 WeakPolarHBondContact O-CG 3.42Å; Y154-P156 VanDerWaalsContact C-CD 3.45Å; P156-L159 PolarHBondContact O-N 3.21Å; P156-G160 PolarHBondContact O-N 3.22Å; P156-Q199 HydrophobicContact CB-CG 3.91Å; P156-A202 HydrophobicContact CB-CB 4.29Å; P156-V203 HydrophobicContact CB-CG2 3.74Å; P156-V203 HydrophobicContact CG-CG2 3.94Å; P156-L388 HydrophobicContact CB-CD2 4.05Å; P156-L388 HydrophobicContact CG-CD1 3.98Å; P156-L388 HydrophobicContact CG-CD2 3.73Å
157	V	95.5	Very high	96.6	Very high	0 Å²	0	17 Å²	17	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-65.6	-50.2	173.9	-179.4	0	0	0	0	109.5	Y154 Y155 L159 G160 W161 Q199 A425 L431	Y154-V157 WeakPolarHBondContact O-CB 3.23Å; Y154-V157 PolarHBondContact O-N 2.91Å; Y155-V157 PolarHBondContact O-N 3.49Å; V157-L159 VanDerWaalsContact C-N 3.3Å; V157-L159 PolarHBondContact O-N 3.48Å; V157-G160 WeakPolarHBondContact O-CA 3.47Å; V157-G160 PolarHBondContact O-N 2.79Å; V157-W161 HydrophobicContact CG1-CZ2 4.02Å; V157-W161 PolarHBondContact O-N 2.95Å; V157-Q199 HydrophobicContact CG2-CB 4.31Å; V157-Q199 HydrophobicContact CG2-CG 3.8Å; V157-A425 HydrophobicContact CG1-CB 4.12Å; V157-A425 HydrophobicContact CG2-CB 3.9Å; V157-L431 HydrophobicContact CB-CD1 4.19Å; V157-L431 HydrophobicContact CG1-CD1 3.85Å
158	V	93.7	Very high	96.5	Very high	7 Å²	7	17.8 Å²	17.8	4%	0.042	8%	0.077	C	C	.	.	H	α-helix	trans	-61.8	-39.2	176.5	-178.4	0	0	0	0	111.2	W77 Y155 W161 C162 L431	W77-V158 HydrophobicContact CH2-CG1 4.47Å; W77-V158 HydrophobicContact CZ2-CG1 3.71Å; Y155-V158 PolarHBondContact O-N 3.41Å; Y155-V158 VanDerWaalsContact O-N 3.16Å; V158-W161 HydrophobicContact CG1-CE3 4.44Å; V158-W161 HydrophobicContact CG2-CE3 4.44Å; V158-W161 HydrophobicContact CG2-CZ3 4.21Å; V158-W161 WeakPolarHBondContact O-CB 3.41Å; V158-W161 PolarHBondContact O-N 3.06Å; V158-C162 PolarHBondContact O-N 3.29Å; V158-C162 VanDerWaalsContact O-N 3.16Å; V158-C162 PolarHBondContact O-SG 3.47Å; V158-L431 HydrophobicContact CG2-CD1 4.42Å
159	L	96.1	Very high	96.4	Very high	0 Å²	0	17.7 Å²	17.7	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-63.2	-41.3	172.3	179	50.2	0	0	0	111.7	Y155 P156 V157 W161 C162 I163 A202 V381 I385 L388	Y155-L159 PolarHBondContact O-N 2.89Å; P156-L159 PolarHBondContact O-N 3.21Å; V157-L159 VanDerWaalsContact C-N 3.3Å; V157-L159 PolarHBondContact O-N 3.48Å; L159-W161 VanDerWaalsContact C-N 3.27Å; L159-W161 PolarHBondContact O-N 3.34Å; L159-C162 WeakPolarHBondContact O-CA 3.5Å; L159-C162 WeakPolarHBondContact O-CB 3.42Å; L159-C162 PolarHBondContact O-N 2.88Å; L159-I163 HydrophobicContact CD1-CG1 4.47Å; L159-I163 HydrophobicContact CG-CD1 4.36Å; L159-I163 WeakPolarHBondContact O-CG1 3.43Å; L159-I163 PolarHBondContact O-N 3.47Å; L159-A202 HydrophobicContact CB-CB 4.12Å; L159-A202 HydrophobicContact CD2-CB 3.85Å; L159-A202 HydrophobicContact CG-CB 3.74Å; L159-V381 HydrophobicContact CD1-CB 4.45Å; L159-V381 HydrophobicContact CD1-CG1 4.45Å; L159-V381 HydrophobicContact CD1-CG2 4.45Å; L159-I385 HydrophobicContact CD1-CG1 4.47Å; L159-I385 HydrophobicContact CD2-CG1 3.95Å; L159-L388 HydrophobicContact CD2-CD2 4.12Å
160	G	96.7	Very high	96.4	Very high	0 Å²	0	18.2 Å²	18.2	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-57.3	-40	173.8	0	0	0	0	0	112.5	P156 V157 C162 I163 Y164 T198	P156-G160 PolarHBondContact O-N 3.22Å; V157-G160 WeakPolarHBondContact O-CA 3.47Å; V157-G160 PolarHBondContact O-N 2.79Å; G160-C162 VanDerWaalsContact C-N 3.34Å; G160-C162 PolarHBondContact O-N 2.98Å; G160-I163 PolarHBondContact O-N 3Å; G160-Y164 PolarHBondContact O-N 3.32Å; G160-T198 WeakPolarHBondContact O-CB 3.27Å; G160-T198 PolarHBondContact O-OG1 2.89Å
161	W	95.5	Very high	96.4	Very high	5 Å²	5	18.2 Å²	18.2	2%	0.019	10%	0.096	C	C	.	.	H	α-helix	trans	-61	-43.8	173	-56.2	-0.9	0	0	0	111.2	V157 V158 L159 I163 Y164 Y165 F188 T351 F355 L428 L431	V157-W161 HydrophobicContact CG1-CZ2 4.02Å; V157-W161 PolarHBondContact O-N 2.95Å; V158-W161 HydrophobicContact CG1-CE3 4.44Å; V158-W161 HydrophobicContact CG2-CE3 4.44Å; V158-W161 HydrophobicContact CG2-CZ3 4.21Å; V158-W161 WeakPolarHBondContact O-CB 3.41Å; V158-W161 PolarHBondContact O-N 3.06Å; L159-W161 VanDerWaalsContact C-N 3.27Å; L159-W161 PolarHBondContact O-N 3.34Å; W161-I163 VanDerWaalsContact C-N 3.33Å; W161-I163 PolarHBondContact O-N 2.82Å; W161-Y164 PolarHBondContact O-N 3.12Å; W161-Y165 VanDerWaalsContact O-CD2 3.29Å; W161-Y165 WeakPolarHBondContact O-CD2 3.35Å; W161-Y165 PolarHBondContact O-N 3.44Å; W161-F188 HydrophobicContact CB-CE1 3.98Å; W161-F188 HydrophobicContact CB-CZ 4.28Å; W161-F188 AromaticContact CD1-CE1 3.17Å; W161-F188 AromaticContact CD1-CZ 3.36Å; W161-F188 HydrophobicContact CD2-CE1 4.39Å; W161-F188 AromaticContact CG-CE1 3.57Å; W161-F188 HydrophobicContact CG-CE1 3.57Å; W161-F188 HydrophobicContact CG-CZ 4.02Å; W161-F188 AromaticContact NE1-CE1 3.64Å; W161-T351 HydrophobicContact CE3-CG2 4.04Å; W161-T351 HydrophobicContact CH2-CG2 3.96Å; W161-T351 HydrophobicContact CZ3-CG2 3.26Å; W161-F355 HydrophobicContact CB-CD1 4.3Å; W161-F355 HydrophobicContact CB-CE1 3.6Å; W161-F355 HydrophobicContact CB-CZ 3.83Å; W161-F355 HydrophobicContact CE3-CD2 4.42Å; W161-F355 AromaticContact CE3-CE2 3.92Å; W161-F355 HydrophobicContact CE3-CE2 3.92Å; W161-F355 HydrophobicContact CE3-CZ 4.06Å; W161-L428 HydrophobicContact CH2-CD1 3.53Å; W161-L428 HydrophobicContact CZ2-CD1 3.84Å; W161-L431 HydrophobicContact CH2-CD1 3.71Å; W161-L431 HydrophobicContact CZ2-CD1 3.74Å
162	C	96.8	Very high	96.3	Very high	0 Å²	0	23.8 Å²	23.8	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-62.3	-40.5	176.9	-57.4	0	0	0	0	111.9	V158 L159 G160 Y165 F166 L380 V381	V158-C162 PolarHBondContact O-N 3.29Å; V158-C162 VanDerWaalsContact O-N 3.16Å; V158-C162 PolarHBondContact O-SG 3.47Å; L159-C162 WeakPolarHBondContact O-CA 3.5Å; L159-C162 WeakPolarHBondContact O-CB 3.42Å; L159-C162 PolarHBondContact O-N 2.88Å; G160-C162 VanDerWaalsContact C-N 3.34Å; G160-C162 PolarHBondContact O-N 2.98Å; C162-Y165 PolarHBondContact O-N 3.05Å; C162-F166 WeakPolarHBondContact O-CB 3.41Å; C162-F166 PolarHBondContact O-N 2.64Å; C162-L380 HydrophobicContact CB-CB 3.95Å; C162-V381 HydrophobicContact CB-CG2 3.87Å
163	I	97.6	Very high	96.2	Very high	20 Å²	20	29.1 Å²	29.1	10%	0.103	15%	0.152	C	C	.	.	H	α-helix	trans	-63.2	-44.9	175.9	-64.9	169.5	0	0	0	110.8	L159 G160 W161 F166 Y167 L201 A202 L205 V381	L159-I163 HydrophobicContact CD1-CG1 4.47Å; L159-I163 HydrophobicContact CG-CD1 4.36Å; L159-I163 WeakPolarHBondContact O-CG1 3.43Å; L159-I163 PolarHBondContact O-N 3.47Å; G160-I163 PolarHBondContact O-N 3Å; W161-I163 VanDerWaalsContact C-N 3.33Å; W161-I163 PolarHBondContact O-N 2.82Å; I163-F166 PolarHBondContact O-N 3.5Å; I163-Y167 PolarHBondContact O-N 2.98Å; I163-L201 HydrophobicContact CG2-CD2 3.9Å; I163-A202 HydrophobicContact CD1-CB 3.87Å; I163-L205 HydrophobicContact CD1-CD1 4.2Å; I163-V381 HydrophobicContact CB-CG2 4.41Å; I163-V381 HydrophobicContact CG1-CG1 4.18Å; I163-V381 HydrophobicContact CG1-CG2 3.75Å
164	Y	96.8	Very high	96.2	Very high	26 Å²	26	29.9 Å²	29.9	10%	0.102	16%	0.155	C	C	.	.	H	α-helix	trans	-61.2	-46.1	177.8	179.7	-106.3	0	0	0	112.2	G160 W161 Y167 I168 F188 W194	G160-Y164 PolarHBondContact O-N 3.32Å; W161-Y164 PolarHBondContact O-N 3.12Å; Y164-Y167 WeakPolarHBondContact O-CB 3.15Å; Y164-Y167 PolarHBondContact O-N 3.28Å; Y164-I168 HydrophobicContact CD1-CD1 3.93Å; Y164-I168 HydrophobicContact CD1-CG1 4.39Å; Y164-I168 HydrophobicContact CE1-CD1 3.18Å; Y164-I168 HydrophobicContact CE1-CG1 4.01Å; Y164-I168 HydrophobicContact CE2-CD1 4.17Å; Y164-I168 HydrophobicContact CE2-CG1 4.37Å; Y164-I168 PolarHBondContact O-N 3.26Å; Y164-I168 WeakPolarHBondContact OH-CD1 3.32Å; Y164-F188 HydrophobicContact CD1-CB 4.07Å; Y164-F188 HydrophobicContact CD1-CD1 4.16Å; Y164-F188 AromaticContact CD1-CD2 3.3Å; Y164-F188 HydrophobicContact CD1-CD2 3.3Å; Y164-F188 HydrophobicContact CD1-CE1 4.46Å; Y164-F188 AromaticContact CD1-CE2 3.68Å; Y164-F188 HydrophobicContact CD1-CE2 3.68Å; Y164-F188 AromaticContact CD1-CG 3.58Å; Y164-F188 HydrophobicContact CD1-CG 3.58Å; Y164-F188 HydrophobicContact CD1-CZ 4.25Å; Y164-F188 AromaticContact CD2-CD2 3.61Å; Y164-F188 HydrophobicContact CD2-CD2 3.61Å; Y164-F188 AromaticContact CD2-CE2 3.75Å; Y164-F188 HydrophobicContact CD2-CE2 3.75Å; Y164-F188 HydrophobicContact CE1-CB 3.46Å; Y164-F188 VanDerWaalsContact CE1-CB 3.46Å; Y164-F188 HydrophobicContact CE1-CD1 4.39Å; Y164-F188 AromaticContact CE1-CD2 3.4Å; Y164-F188 HydrophobicContact CE1-CD2 3.4Å; Y164-F188 VanDerWaalsContact CE1-CD2 3.4Å; Y164-F188 HydrophobicContact CE1-CE2 4.25Å; Y164-F188 AromaticContact CE1-CG 3.5Å; Y164-F188 HydrophobicContact CE1-CG 3.5Å; Y164-F188 VanDerWaalsContact CE1-CG 3.5Å; Y164-F188 AromaticContact CE2-CD2 3.72Å; Y164-F188 HydrophobicContact CE2-CD2 3.72Å; Y164-F188 HydrophobicContact CE2-CE2 4.32Å; Y164-F188 AromaticContact CG-CD2 3.38Å; Y164-F188 HydrophobicContact CG-CD2 3.38Å; Y164-F188 AromaticContact CG-CE2 3.37Å; Y164-F188 HydrophobicContact CG-CE2 3.37Å; Y164-F188 HydrophobicContact CG-CG 4.14Å; Y164-F188 HydrophobicContact CG-CZ 4.12Å; Y164-F188 AromaticContact CZ-CD2 3.59Å; Y164-W194 HydrophobicContact CD2-CD2 4.06Å; Y164-W194 AromaticContact CD2-CE3 3.86Å; Y164-W194 HydrophobicContact CD2-CE3 3.86Å; Y164-W194 HydrophobicContact CD2-CG 4.4Å; Y164-W194 HydrophobicContact CD2-CZ3 4.34Å; Y164-W194 HydrophobicContact CE2-CB 4.48Å; Y164-W194 AromaticContact CE2-CD2 3.75Å; Y164-W194 HydrophobicContact CE2-CD2 3.75Å; Y164-W194 AromaticContact CE2-CE3 4Å; Y164-W194 HydrophobicContact CE2-CE3 4Å; Y164-W194 AromaticContact CE2-CG 3.98Å; Y164-W194 HydrophobicContact CE2-CG 3.98Å; Y164-W194 HydrophobicContact CE2-CZ3 4.49Å
165	Y	96.9	Very high	96.2	Very high	3 Å²	3	30 Å²	30	1%	0.012	16%	0.157	C	C	.	.	H	α-helix	trans	-71.1	-30.6	179.7	-87.1	-101.6	0	0	0	113	W161 C162 S169 V184 F185 F355 P359 F377	W161-Y165 VanDerWaalsContact O-CD2 3.29Å; W161-Y165 WeakPolarHBondContact O-CD2 3.35Å; W161-Y165 PolarHBondContact O-N 3.44Å; C162-Y165 PolarHBondContact O-N 3.05Å; Y165-S169 VanDerWaalsContact O-CB 3.29Å; Y165-S169 WeakPolarHBondContact O-CB 3.24Å; Y165-S169 PolarHBondContact O-N 3.08Å; Y165-S169 PolarHBondContact O-OG 3.22Å; Y165-V184 HydrophobicContact CE1-CG1 4.32Å; Y165-F185 WeakPolarHBondContact OH-CA 3.38Å; Y165-F185 WeakPolarHBondContact OH-CB 3.38Å; Y165-F355 HydrophobicContact CD1-CD1 4.29Å; Y165-F355 AromaticContact CD2-CD1 3.53Å; Y165-F355 HydrophobicContact CD2-CD1 3.53Å; Y165-F355 HydrophobicContact CD2-CE1 4.1Å; Y165-F355 HydrophobicContact CE1-CB 4.21Å; Y165-F355 HydrophobicContact CE1-CD1 4.33Å; Y165-F355 WeakPolarHBondContact CE1-O 3.36Å; Y165-F355 HydrophobicContact CE2-CB 4.11Å; Y165-F355 AromaticContact CE2-CD1 3.58Å; Y165-F355 HydrophobicContact CE2-CD1 3.58Å; Y165-F355 HydrophobicContact CE2-CE1 4.48Å; Y165-F355 HydrophobicContact CE2-CG 4.28Å; Y165-F355 AromaticContact CG-CD1 3.89Å; Y165-F355 HydrophobicContact CG-CD1 3.89Å; Y165-F355 HydrophobicContact CG-CE1 4.45Å; Y165-F355 AromaticContact CZ-CD1 3.98Å; Y165-F355 PolarHBondContact OH-O 3.34Å; Y165-P359 HydrophobicContact CD1-CG 3.96Å; Y165-P359 HydrophobicContact CE1-CG 3.92Å; Y165-F377 VanDerWaalsContact CB-CD1 3.42Å; Y165-F377 HydrophobicContact CD1-CE1 4.05Å; Y165-F377 AromaticContact CD1-CE2 3.83Å; Y165-F377 HydrophobicContact CD1-CE2 3.83Å; Y165-F377 AromaticContact CD1-CZ 3.47Å; Y165-F377 HydrophobicContact CD1-CZ 3.47Å; Y165-F377 VanDerWaalsContact CD1-CZ 3.47Å; Y165-F377 HydrophobicContact CE1-CZ 4.41Å; Y165-F377 HydrophobicContact CG-CD1 4.35Å; Y165-F377 AromaticContact CG-CE1 3.81Å; Y165-F377 HydrophobicContact CG-CE1 3.81Å; Y165-F377 HydrophobicContact CG-CE2 4.19Å; Y165-F377 AromaticContact CG-CZ 3.72Å; Y165-F377 HydrophobicContact CG-CZ 3.72Å
166	F	97.9	Very high	96.2	Very high	64 Å²	64	35.8 Å²	35.8	28%	0.281	18%	0.182	S	C	.	.	H	α-helix	trans	-60.5	-48.3	167.6	176.3	-117.9	0	0	0	110.8	C162 I163 S169 C170 A374 F377 L378	C162-F166 WeakPolarHBondContact O-CB 3.41Å; C162-F166 PolarHBondContact O-N 2.64Å; I163-F166 PolarHBondContact O-N 3.5Å; F166-S169 PolarHBondContact O-N 2.71Å; F166-C170 PolarHBondContact O-N 3.25Å; F166-C170 VanDerWaalsContact O-N 3.12Å; F166-C170 PolarHBondContact O-SG 3.23Å; F166-C170 VanDerWaalsContact O-SG 3.36Å; F166-A374 HydrophobicContact CD2-CB 4.35Å; F166-A374 VanDerWaalsContact CD2-O 3.23Å; F166-A374 WeakPolarHBondContact CD2-O 3.43Å; F166-A374 HydrophobicContact CE2-CB 4.2Å; F166-F377 HydrophobicContact CB-CB 3.85Å; F166-L378 HydrophobicContact CD2-CB 3.88Å; F166-L378 HydrophobicContact CE1-CD1 4.41Å; F166-L378 HydrophobicContact CE2-CB 3.74Å; F166-L378 HydrophobicContact CE2-CD1 4.24Å; F166-L378 HydrophobicContact CE2-CD2 4.4Å; F166-L378 HydrophobicContact CE2-CG 4.35Å; F166-L378 HydrophobicContact CZ-CB 4.44Å; F166-L378 HydrophobicContact CZ-CD1 4.09Å
167	Y	97.1	Very high	96	Very high	99 Å²	99	38.6 Å²	38.6	39%	0.388	20%	0.2	S	C	.	.	H	α-helix	trans	-59.1	-48.7	175.7	166	-111.7	0	0	0	112.2	I163 Y164 S169 C170 A171 Y172 W194	I163-Y167 PolarHBondContact O-N 2.98Å; Y164-Y167 WeakPolarHBondContact O-CB 3.15Å; Y164-Y167 PolarHBondContact O-N 3.28Å; Y167-S169 VanDerWaalsContact C-N 3.31Å; Y167-S169 PolarHBondContact O-N 3.07Å; Y167-C170 CarbonylContact O-C 3.24Å; Y167-C170 PolarHBondContact O-N 3.13Å; Y167-C170 VanDerWaalsContact O-N 3.1Å; Y167-A171 HydrophobicContact CD2-CB 4.05Å; Y167-A171 HydrophobicContact CE2-CB 3.64Å; Y167-A171 VanDerWaalsContact O-CB 3.29Å; Y167-A171 WeakPolarHBondContact O-CB 3.48Å; Y167-A171 PolarHBondContact O-N 3Å; Y167-Y172 AromaticContact CE1-CE2 3.81Å; Y167-Y172 HydrophobicContact CE1-CE2 3.81Å; Y167-Y172 AromaticContact CZ-CE2 3.87Å; Y167-W194 HydrophobicContact CE1-CH2 4.49Å
168	I	95.5	Very high	95.7	Very high	16 Å²	16	42.8 Å²	42.8	8%	0.082	22%	0.22	C	C	.	.	H	α-helix	trans	-58.3	-45.3	177.1	-76.6	-168.8	0	0	0	111.3	Y164 C170 A171 Y172 V184	Y164-I168 HydrophobicContact CD1-CD1 3.93Å; Y164-I168 HydrophobicContact CD1-CG1 4.39Å; Y164-I168 HydrophobicContact CE1-CD1 3.18Å; Y164-I168 HydrophobicContact CE1-CG1 4.01Å; Y164-I168 HydrophobicContact CE2-CD1 4.17Å; Y164-I168 HydrophobicContact CE2-CG1 4.37Å; Y164-I168 PolarHBondContact O-N 3.26Å; Y164-I168 WeakPolarHBondContact OH-CD1 3.32Å; I168-C170 PolarHBondContact O-N 3.14Å; I168-A171 PolarHBondContact O-N 3.38Å; I168-Y172 HydrophobicContact CG1-CD2 4.32Å; I168-Y172 PolarHBondContact O-N 2.96Å; I168-V184 HydrophobicContact CD1-CG1 3.75Å
169	S	97	Very high	95.6	Very high	1 Å²	1	50.1 Å²	50.1	1%	0.007	25%	0.253	C	S	.	.	H	α-helix	trans	-58.8	-34	179.6	-60.1	0	0	0	0	111.7	Y165 F166 Y167 R370 C373	Y165-S169 VanDerWaalsContact O-CB 3.29Å; Y165-S169 WeakPolarHBondContact O-CB 3.24Å; Y165-S169 PolarHBondContact O-N 3.08Å; Y165-S169 PolarHBondContact O-OG 3.22Å; F166-S169 PolarHBondContact O-N 2.71Å; Y167-S169 VanDerWaalsContact C-N 3.31Å; Y167-S169 PolarHBondContact O-N 3.07Å; S169-R370 WeakPolarHBondContact O-CG 3.34Å; S169-R370 PolarHBondContact O-NE 2.87Å; S169-C373 PolarHBondContact OG-SG 3.04Å
170	C	97.4	Very high	95.5	Very high	67 Å²	67	54.3 Å²	54.3	45%	0.453	27%	0.273	S	S	.	.	H	α-helix	trans	-85	-30.5	178.5	-68.1	0	0	0	0	114.4	F166 Y167 I168 R370	F166-C170 PolarHBondContact O-N 3.25Å; F166-C170 VanDerWaalsContact O-N 3.12Å; F166-C170 PolarHBondContact O-SG 3.23Å; F166-C170 VanDerWaalsContact O-SG 3.36Å; Y167-C170 CarbonylContact O-C 3.24Å; Y167-C170 PolarHBondContact O-N 3.13Å; Y167-C170 VanDerWaalsContact O-N 3.1Å; I168-C170 PolarHBondContact O-N 3.14Å; C170-R370 PolarHBondContact O-NH2 3.43Å
171	A	96.1	Very high	95.3	Very high	47 Å²	47	54.3 Å²	54.3	39%	0.388	27%	0.273	S	S	.	.	H	α-helix	trans	-104.5	-32.4	-169	0	0	0	0	0	114.1	Y167 I168 R370	Y167-A171 HydrophobicContact CD2-CB 4.05Å; Y167-A171 HydrophobicContact CE2-CB 3.64Å; Y167-A171 VanDerWaalsContact O-CB 3.29Å; Y167-A171 WeakPolarHBondContact O-CB 3.48Å; Y167-A171 PolarHBondContact O-N 3Å; I168-A171 PolarHBondContact O-N 3.38Å; A171-R370 PolarHBondContact O-NH2 3.42Å
172	Y	94.7	Very high	95.2	Very high	120 Å²	120	57.2 Å²	57.2	47%	0.471	29%	0.289	S	S	.	.	S	Bend	trans	-121.6	161.1	-172.4	-63	-84.5	0	0	0	112.5	Y167 I168 R370	Y167-Y172 AromaticContact CE1-CE2 3.81Å; Y167-Y172 HydrophobicContact CE1-CE2 3.81Å; Y167-Y172 AromaticContact CZ-CE2 3.87Å; I168-Y172 HydrophobicContact CG1-CD2 4.32Å; I168-Y172 PolarHBondContact O-N 2.96Å; Y172-R370 PolarHBondContact O-NH2 2.89Å
173	P	94.8	Very high	95	Very high	116 Å²	116	59.1 Å²	59.1	75%	0.753	30%	0.304	S	S	*	.	P	Polyproline II helix	trans	-60.3	142.5	166.3	-21.5	33.8	0	0	0	111.5
174	L	96.6	Very high	94.8	Very high	18 Å²	18	59.8 Å²	59.8	9%	0.094	31%	0.309	C	S	.	.	P	Polyproline II helix	trans	-72.8	145.5	176	-62.8	-177	0	0	0	111.2	P359 F362 R370 C373	L174-P359 HydrophobicContact CD2-CB 4.46Å; L174-F362 HydrophobicContact CD1-CB 4.1Å; L174-R370 HydrophobicContact CD1-CB 4.42Å; L174-C373 HydrophobicContact CD1-CB 3.83Å; L174-C373 HydrophobicContact CD2-CB 4.2Å
175	P	96.1	Very high	94.5	Very high	9 Å²	9	58.6 Å²	58.6	6%	0.058	30%	0.304	C	S	.	.	P	Polyproline II helix	trans	-62.5	147	173	28.9	-36	0	0	0	110.6	E180 P359 V360 S363	P175-E180 WeakPolarHBondContact CA-OE2 3.35Å; P175-E180 HydrophobicContact CB-CB 3.62Å; P175-P359 HydrophobicContact CG-CB 3.69Å; P175-V360 HydrophobicContact CB-CG2 4.12Å; P175-V360 HydrophobicContact CG-CG2 3.96Å; P175-V360 WeakPolarHBondContact O-CA 3.33Å; P175-S363 WeakPolarHBondContact O-CB 3.34Å; P175-S363 PolarHBondContact O-OG 3.31Å
176	K	94	Very high	94.3	Very high	133 Å²	133	60.1 Å²	60.1	58%	0.578	31%	0.313	S	S	*	.			trans	-107.6	-17.7	-174.2	-64.7	-179.7	-178.3	175.4	0	113.7	E180 K364	K176-E180 PolarHBondContact N-OE2 3.43Å; K176-K364 PolarHBondContact O-NZ 2.87Å
177	T	92.3	Very high	93.9	Very high	60 Å²	60	60.9 Å²	60.9	37%	0.368	32%	0.32	S	S	.	.	S	Bend	trans	-128.5	160.8	-178.7	68.1	0	0	0	0	110.8	E179 E180 G181 V360	T177-E179 VanDerWaalsContact C-N 3.27Å; T177-E179 PolarHBondContact O-N 3.4Å; T177-E180 PolarHBondContact O-N 3.4Å; T177-E180 WeakPolarHBondContact OG1-CG 3.41Å; T177-E180 PolarHBondContact OG1-N 3.3Å; T177-E180 VanDerWaalsContact OG1-N 3.15Å; T177-G181 PolarHBondContact O-N 3.4Å; T177-V360 WeakPolarHBondContact O-CG2 3.41Å
178	E	89.4	Confident	93.6	Very high	88 Å²	88	56.1 Å²	56.1	41%	0.411	30%	0.301	S	S	.	.	H	α-helix	trans	-57.4	-42.2	174.1	-179.2	173.4	-155.6	0	0	111.8	G181 L182 T356 W357	E178-G181 PolarHBondContact O-N 3.09Å; E178-L182 WeakPolarHBondContact O-CB 3.39Å; E178-L182 PolarHBondContact O-N 3.15Å; E178-T356 HydrophobicContact CG-CG2 4.26Å; E178-W357 HydrophobicContact CB-CH2 3.76Å; E178-W357 HydrophobicContact CB-CZ2 3.62Å; E178-W357 HydrophobicContact CB-CZ3 4.41Å; E178-W357 HydrophobicContact CG-CH2 4.28Å; E178-W357 HydrophobicContact CG-CZ2 3.61Å; E178-W357 WeakPolarHBondContact OE1-CZ2 3.49Å; E178-W357 PolarHBondContact OE1-NE1 2.76Å; E178-W357 VanDerWaalsContact OE2-CZ2 3.29Å; E178-W357 WeakPolarHBondContact OE2-CZ2 3.33Å
179	E	91.9	Very high	93.2	Very high	160 Å²	160	56 Å²	56	75%	0.748	30%	0.303	S	S	*	.	H	α-helix	trans	-60.3	-46.2	177.9	-175	-180	-177.7	0	0	111.7	T177 G181 L182 A183	T177-E179 VanDerWaalsContact C-N 3.27Å; T177-E179 PolarHBondContact O-N 3.4Å; E179-G181 VanDerWaalsContact C-N 3.35Å; E179-G181 PolarHBondContact O-N 2.91Å; E179-L182 PolarHBondContact O-N 3.04Å; E179-A183 WeakPolarHBondContact O-CB 3.44Å; E179-A183 PolarHBondContact O-N 3.47Å
180	E	94.6	Very high	92.6	Very high	88 Å²	88	61.7 Å²	61.7	41%	0.411	33%	0.329	S	S	.	.	H	α-helix	trans	-63	-41.5	174.9	-72.7	173.3	-158.9	0	0	111.5	P175 K176 T177 L182 A183 V184	P175-E180 WeakPolarHBondContact CA-OE2 3.35Å; P175-E180 HydrophobicContact CB-CB 3.62Å; K176-E180 PolarHBondContact N-OE2 3.43Å; T177-E180 PolarHBondContact O-N 3.4Å; T177-E180 WeakPolarHBondContact OG1-CG 3.41Å; T177-E180 PolarHBondContact OG1-N 3.3Å; T177-E180 VanDerWaalsContact OG1-N 3.15Å; E180-L182 PolarHBondContact O-N 2.74Å; E180-A183 PolarHBondContact O-N 2.85Å; E180-V184 WeakPolarHBondContact O-CG2 3.41Å; E180-V184 PolarHBondContact O-N 3.04Å
181	G	93.1	Very high	91.9	Very high	0 Å²	0	65 Å²	65	0%	0	34%	0.338	C	S	.	.	H	α-helix	trans	-63.4	-40.3	177.1	0	0	0	0	0	112.7	T177 E178 E179 V184 F185	T177-G181 PolarHBondContact O-N 3.4Å; E178-G181 PolarHBondContact O-N 3.09Å; E179-G181 VanDerWaalsContact C-N 3.35Å; E179-G181 PolarHBondContact O-N 2.91Å; G181-V184 PolarHBondContact O-N 3.37Å; G181-F185 PolarHBondContact O-N 3.16Å; G181-F185 VanDerWaalsContact O-N 3.16Å
182	L	91.5	Very high	91.6	Very high	67 Å²	67	64.4 Å²	64.4	35%	0.351	33%	0.331	S	S	.	.	H	α-helix	trans	-70.7	-38.5	177.4	-175.8	62.4	0	0	0	110.7	E178 E179 E180 V184 F185 N186 T356	E178-L182 WeakPolarHBondContact O-CB 3.39Å; E178-L182 PolarHBondContact O-N 3.15Å; E179-L182 PolarHBondContact O-N 3.04Å; E180-L182 PolarHBondContact O-N 2.74Å; L182-V184 PolarHBondContact O-N 3.46Å; L182-F185 PolarHBondContact O-N 3.3Å; L182-N186 WeakPolarHBondContact O-CB 3.43Å; L182-N186 VanDerWaalsContact O-CG 3.29Å; L182-N186 PolarHBondContact O-N 2.97Å; L182-T356 HydrophobicContact CB-CG2 4.17Å
183	A	92.6	Very high	91.4	Very high	39 Å²	39	68 Å²	68	32%	0.322	35%	0.345	S	S	.	.	H	α-helix	trans	-61.2	-42.7	174	0	0	0	0	0	111.6	E179 E180 F185 N186 N187	E179-A183 WeakPolarHBondContact O-CB 3.44Å; E179-A183 PolarHBondContact O-N 3.47Å; E180-A183 PolarHBondContact O-N 2.85Å; A183-F185 VanDerWaalsContact C-N 3.32Å; A183-F185 PolarHBondContact O-N 3.25Å; A183-N186 PolarHBondContact O-N 2.8Å; A183-N187 WeakPolarHBondContact O-CB 3.4Å; A183-N187 PolarHBondContact O-N 3.04Å; A183-N187 PolarHBondContact O-ND2 3.18Å
184	V	93.6	Very high	91.4	Very high	35 Å²	35	67.4 Å²	67.4	21%	0.212	33%	0.328	C	S	.	.	H	α-helix	trans	-59.2	-44.4	174	171.6	0	0	0	0	111.1	Y165 I168 E180 G181 L182 F188	Y165-V184 HydrophobicContact CE1-CG1 4.32Å; I168-V184 HydrophobicContact CD1-CG1 3.75Å; E180-V184 WeakPolarHBondContact O-CG2 3.41Å; E180-V184 PolarHBondContact O-N 3.04Å; G181-V184 PolarHBondContact O-N 3.37Å; L182-V184 PolarHBondContact O-N 3.46Å; V184-F188 WeakPolarHBondContact O-CB 3.39Å; V184-F188 PolarHBondContact O-N 3.41Å
185	F	92.2	Very high	91.3	Very high	0 Å²	0	66.6 Å²	66.6	0%	0	32%	0.324	C	S	.	.	H	α-helix	trans	-64.8	-48.7	177.9	-177.5	-99.5	0	0	0	112	Y165 G181 L182 A183 F188 A189 P348 F355	Y165-F185 WeakPolarHBondContact OH-CA 3.38Å; Y165-F185 WeakPolarHBondContact OH-CB 3.38Å; G181-F185 PolarHBondContact O-N 3.16Å; G181-F185 VanDerWaalsContact O-N 3.16Å; L182-F185 PolarHBondContact O-N 3.3Å; A183-F185 VanDerWaalsContact C-N 3.32Å; A183-F185 PolarHBondContact O-N 3.25Å; F185-F188 CarbonylContact O-C 3.19Å; F185-F188 WeakPolarHBondContact O-CB 3.35Å; F185-F188 PolarHBondContact O-N 3.42Å; F185-F188 VanDerWaalsContact O-N 3.14Å; F185-A189 HydrophobicContact CD1-CB 4.24Å; F185-A189 HydrophobicContact CD2-CB 4.48Å; F185-A189 HydrophobicContact CE1-CB 3.78Å; F185-A189 HydrophobicContact CE2-CB 4.07Å; F185-A189 HydrophobicContact CZ-CB 3.7Å; F185-A189 WeakPolarHBondContact O-CB 3.33Å; F185-A189 PolarHBondContact O-N 3.31Å; F185-P348 HydrophobicContact CE1-CB 4.09Å; F185-P348 HydrophobicContact CE1-CG 4.18Å; F185-F355 HydrophobicContact CD2-CB 3.82Å; F185-F355 HydrophobicContact CE2-CB 4.24Å
186	N	90.9	Very high	91.3	Very high	35 Å²	35	67.7 Å²	67.7	19%	0.187	33%	0.33	C	S	.	.	H	α-helix	trans	-66.1	-41.4	-177.8	-68	-6.9	0	0	0	112.1	L182 A183 F188 E190 Q191	L182-N186 WeakPolarHBondContact O-CB 3.43Å; L182-N186 VanDerWaalsContact O-CG 3.29Å; L182-N186 PolarHBondContact O-N 2.97Å; A183-N186 PolarHBondContact O-N 2.8Å; N186-F188 PolarHBondContact O-N 2.92Å; N186-E190 PolarHBondContact O-N 3.21Å; N186-Q191 PolarHBondContact O-N 3.11Å
187	N	91.2	Very high	91.5	Very high	80 Å²	80	66.4 Å²	66.4	43%	0.428	33%	0.329	S	S	.	.	H	α-helix	trans	-58	-33.4	174.9	-73.1	-13.8	0	0	0	111.6	A183 Q191 S192	A183-N187 WeakPolarHBondContact O-CB 3.4Å; A183-N187 PolarHBondContact O-N 3.04Å; A183-N187 PolarHBondContact O-ND2 3.18Å; N187-Q191 PolarHBondContact OD1-OE1 3.3Å; N187-Q191 VanDerWaalsContact OD1-OE1 3.07Å; N187-S192 VanDerWaalsContact O-CB 3.24Å; N187-S192 WeakPolarHBondContact O-CB 3.38Å; N187-S192 PolarHBondContact O-OG 3.05Å
188	F	90.4	Very high	91.7	Very high	0 Å²	0	63.8 Å²	63.8	0%	0	31%	0.313	C	S	.	.	H	α-helix	trans	-81	-62.9	175.5	168.3	-104.6	0	0	0	112.1	W161 Y164 V184 F185 N186 S192 W194 P195 T198	W161-F188 HydrophobicContact CB-CE1 3.98Å; W161-F188 HydrophobicContact CB-CZ 4.28Å; W161-F188 AromaticContact CD1-CE1 3.17Å; W161-F188 AromaticContact CD1-CZ 3.36Å; W161-F188 HydrophobicContact CD2-CE1 4.39Å; W161-F188 AromaticContact CG-CE1 3.57Å; W161-F188 HydrophobicContact CG-CE1 3.57Å; W161-F188 HydrophobicContact CG-CZ 4.02Å; W161-F188 AromaticContact NE1-CE1 3.64Å; Y164-F188 HydrophobicContact CD1-CB 4.07Å; Y164-F188 HydrophobicContact CD1-CD1 4.16Å; Y164-F188 AromaticContact CD1-CD2 3.3Å; Y164-F188 HydrophobicContact CD1-CD2 3.3Å; Y164-F188 HydrophobicContact CD1-CE1 4.46Å; Y164-F188 AromaticContact CD1-CE2 3.68Å; Y164-F188 HydrophobicContact CD1-CE2 3.68Å; Y164-F188 AromaticContact CD1-CG 3.58Å; Y164-F188 HydrophobicContact CD1-CG 3.58Å; Y164-F188 HydrophobicContact CD1-CZ 4.25Å; Y164-F188 AromaticContact CD2-CD2 3.61Å; Y164-F188 HydrophobicContact CD2-CD2 3.61Å; Y164-F188 AromaticContact CD2-CE2 3.75Å; Y164-F188 HydrophobicContact CD2-CE2 3.75Å; Y164-F188 HydrophobicContact CE1-CB 3.46Å; Y164-F188 VanDerWaalsContact CE1-CB 3.46Å; Y164-F188 HydrophobicContact CE1-CD1 4.39Å; Y164-F188 AromaticContact CE1-CD2 3.4Å; Y164-F188 HydrophobicContact CE1-CD2 3.4Å; Y164-F188 VanDerWaalsContact CE1-CD2 3.4Å; Y164-F188 HydrophobicContact CE1-CE2 4.25Å; Y164-F188 AromaticContact CE1-CG 3.5Å; Y164-F188 HydrophobicContact CE1-CG 3.5Å; Y164-F188 VanDerWaalsContact CE1-CG 3.5Å; Y164-F188 AromaticContact CE2-CD2 3.72Å; Y164-F188 HydrophobicContact CE2-CD2 3.72Å; Y164-F188 HydrophobicContact CE2-CE2 4.32Å; Y164-F188 AromaticContact CG-CD2 3.38Å; Y164-F188 HydrophobicContact CG-CD2 3.38Å; Y164-F188 AromaticContact CG-CE2 3.37Å; Y164-F188 HydrophobicContact CG-CE2 3.37Å; Y164-F188 HydrophobicContact CG-CG 4.14Å; Y164-F188 HydrophobicContact CG-CZ 4.12Å; Y164-F188 AromaticContact CZ-CD2 3.59Å; V184-F188 WeakPolarHBondContact O-CB 3.39Å; V184-F188 PolarHBondContact O-N 3.41Å; F185-F188 CarbonylContact O-C 3.19Å; F185-F188 WeakPolarHBondContact O-CB 3.35Å; F185-F188 PolarHBondContact O-N 3.42Å; F185-F188 VanDerWaalsContact O-N 3.14Å; N186-F188 PolarHBondContact O-N 2.92Å; F188-S192 PolarHBondContact O-OG 3.16Å; F188-W194 HydrophobicContact CD2-CB 3.3Å; F188-W194 HydrophobicContact CD2-CG 4.1Å; F188-W194 HydrophobicContact CE2-CB 3.48Å; F188-W194 VanDerWaalsContact CE2-CB 3.48Å; F188-W194 HydrophobicContact CG-CB 4.45Å; F188-P195 HydrophobicContact CD1-CG 4.43Å; F188-P195 HydrophobicContact CE1-CG 4.14Å; F188-P195 HydrophobicContact CE2-CG 4.22Å; F188-P195 HydrophobicContact CZ-CB 4.33Å; F188-P195 HydrophobicContact CZ-CG 4.02Å; F188-P195 WeakPolarHBondContact O-CD 3.36Å; F188-P195 WeakPolarHBondContact O-CG 3.48Å; F188-T198 HydrophobicContact CE2-CG2 4.45Å
189	A	87.1	Confident	92.1	Very high	14 Å²	14	59.6 Å²	59.6	12%	0.116	29%	0.293	C	S	.	.	H	α-helix	trans	-75.3	-31.7	-166.4	0	0	0	0	0	114.5	F185	F185-A189 HydrophobicContact CD1-CB 4.24Å; F185-A189 HydrophobicContact CD2-CB 4.48Å; F185-A189 HydrophobicContact CE1-CB 3.78Å; F185-A189 HydrophobicContact CE2-CB 4.07Å; F185-A189 HydrophobicContact CZ-CB 3.7Å; F185-A189 WeakPolarHBondContact O-CB 3.33Å; F185-A189 PolarHBondContact O-N 3.31Å
190	E	83.9	Confident	92.3	Very high	119 Å²	119	56.4 Å²	56.4	56%	0.556	28%	0.277	S	S	*	.	T	Hydrogen-bonded Turn	trans	-115.6	-33	-171.5	-63.9	-176.9	175.6	0	0	113.2	N186	N186-E190 PolarHBondContact O-N 3.21Å
191	Q	83.8	Confident	92.5	Very high	136 Å²	136	55.9 Å²	55.9	64%	0.636	28%	0.277	S	S	*	.	T	Hydrogen-bonded Turn	trans	-104.1	8.7	-170.8	-55.8	179.5	10.4	0	0	113.8	N186 N187	N186-Q191 PolarHBondContact O-N 3.11Å; N187-Q191 PolarHBondContact OD1-OE1 3.3Å; N187-Q191 VanDerWaalsContact OD1-OE1 3.07Å
192	S	89.2	Confident	92.7	Very high	35 Å²	35	55.9 Å²	55.9	25%	0.245	28%	0.277	C	S	.	.	S	Bend	trans	-147.8	170	-176.7	83.8	0	0	0	0	113.3	N187 F188 W194	N187-S192 VanDerWaalsContact O-CB 3.24Å; N187-S192 WeakPolarHBondContact O-CB 3.38Å; N187-S192 PolarHBondContact O-OG 3.05Å; F188-S192 PolarHBondContact O-OG 3.16Å; S192-W194 VanDerWaalsContact C-N 3.33Å; S192-W194 VanDerWaalsContact OG-CB 3.32Å; S192-W194 WeakPolarHBondContact OG-CB 3.33Å; S192-W194 PolarHBondContact OG-N 3.31Å; S192-W194 VanDerWaalsContact OG-N 3.13Å
193	Y	89.9	Confident	93	Very high	197 Å²	197	53.2 Å²	53.2	77%	0.773	26%	0.263	S	S	*	.	S	Bend	trans	-92.5	10	171.7	-57.4	-69.6	0	0	0	113.2	P195 V196 L197	Y193-P195 VanDerWaalsContact C-CD 3.48Å; Y193-V196 PolarHBondContact O-N 3.34Å; Y193-L197 PolarHBondContact O-N 3.14Å; Y193-L197 VanDerWaalsContact O-N 3.08Å
194	W	94.3	Very high	93.2	Very high	102 Å²	102	53.8 Å²	53.8	39%	0.386	27%	0.268	S	S	.	.	H	α-helix	trans	-58.1	-39.4	178.3	-80.9	109.3	0	0	0	114.1	Y164 Y167 F188 S192 V196 L197 T198	Y164-W194 HydrophobicContact CD2-CD2 4.06Å; Y164-W194 AromaticContact CD2-CE3 3.86Å; Y164-W194 HydrophobicContact CD2-CE3 3.86Å; Y164-W194 HydrophobicContact CD2-CG 4.4Å; Y164-W194 HydrophobicContact CD2-CZ3 4.34Å; Y164-W194 HydrophobicContact CE2-CB 4.48Å; Y164-W194 AromaticContact CE2-CD2 3.75Å; Y164-W194 HydrophobicContact CE2-CD2 3.75Å; Y164-W194 AromaticContact CE2-CE3 4Å; Y164-W194 HydrophobicContact CE2-CE3 4Å; Y164-W194 AromaticContact CE2-CG 3.98Å; Y164-W194 HydrophobicContact CE2-CG 3.98Å; Y164-W194 HydrophobicContact CE2-CZ3 4.49Å; Y167-W194 HydrophobicContact CE1-CH2 4.49Å; F188-W194 HydrophobicContact CD2-CB 3.3Å; F188-W194 HydrophobicContact CD2-CG 4.1Å; F188-W194 HydrophobicContact CE2-CB 3.48Å; F188-W194 VanDerWaalsContact CE2-CB 3.48Å; F188-W194 HydrophobicContact CG-CB 4.45Å; S192-W194 VanDerWaalsContact C-N 3.33Å; S192-W194 VanDerWaalsContact OG-CB 3.32Å; S192-W194 WeakPolarHBondContact OG-CB 3.33Å; S192-W194 PolarHBondContact OG-N 3.31Å; S192-W194 VanDerWaalsContact OG-N 3.13Å; W194-V196 VanDerWaalsContact C-N 3.29Å; W194-V196 PolarHBondContact O-N 3.33Å; W194-L197 HydrophobicContact CE3-CD2 4.04Å; W194-L197 HydrophobicContact CZ3-CD2 3.98Å; W194-L197 PolarHBondContact O-N 3.28Å; W194-T198 HydrophobicContact CE3-CG2 4.09Å; W194-T198 WeakPolarHBondContact O-CB 3.31Å; W194-T198 WeakPolarHBondContact O-CG2 3.43Å; W194-T198 PolarHBondContact O-N 3.38Å; W194-T198 PolarHBondContact O-OG1 3.48Å
195	P	95	Very high	93.4	Very high	2 Å²	2	55.3 Å²	55.3	1%	0.013	27%	0.274	C	S	.	.	H	α-helix	trans	-60.6	-40	177.6	-26.6	36.5	0	0	0	112	F188 Y193 T198 Q199 A425	F188-P195 HydrophobicContact CD1-CG 4.43Å; F188-P195 HydrophobicContact CE1-CG 4.14Å; F188-P195 HydrophobicContact CE2-CG 4.22Å; F188-P195 HydrophobicContact CZ-CB 4.33Å; F188-P195 HydrophobicContact CZ-CG 4.02Å; F188-P195 WeakPolarHBondContact O-CD 3.36Å; F188-P195 WeakPolarHBondContact O-CG 3.48Å; Y193-P195 VanDerWaalsContact C-CD 3.48Å; P195-T198 PolarHBondContact O-OG1 3.32Å; P195-Q199 WeakPolarHBondContact O-CB 3.27Å; P195-Q199 PolarHBondContact O-N 3.23Å; P195-A425 HydrophobicContact CB-CB 4.15Å; P195-A425 VanDerWaalsContact CB-O 3.26Å; P195-A425 WeakPolarHBondContact CB-O 3.46Å
196	V	96.9	Very high	93.5	Very high	31 Å²	31	55.3 Å²	55.3	19%	0.188	27%	0.274	C	S	.	.	H	α-helix	trans	-64.3	-52.5	175.2	-178	0	0	0	0	109.8	Y193 W194 T198 Q199 F200 V422 A425 I426	Y193-V196 PolarHBondContact O-N 3.34Å; W194-V196 VanDerWaalsContact C-N 3.29Å; W194-V196 PolarHBondContact O-N 3.33Å; V196-T198 VanDerWaalsContact C-N 3.32Å; V196-T198 PolarHBondContact O-N 3.49Å; V196-Q199 PolarHBondContact O-N 3.18Å; V196-F200 HydrophobicContact CG1-CD2 3.88Å; V196-F200 HydrophobicContact CG1-CE2 3.84Å; V196-F200 VanDerWaalsContact O-CD2 3.27Å; V196-F200 WeakPolarHBondContact O-CD2 3.37Å; V196-F200 PolarHBondContact O-N 3.09Å; V196-V422 HydrophobicContact CG2-CG1 4.49Å; V196-A425 HydrophobicContact CG2-CB 3.97Å; V196-I426 HydrophobicContact CG2-CG2 3.56Å
197	L	96.8	Very high	93.7	Very high	107 Å²	107	54.1 Å²	54.1	56%	0.56	27%	0.271	S	S	*	.	H	α-helix	trans	-56.5	-46	-179.7	177.7	61.8	0	0	0	112.3	Y193 W194 F200 L201	Y193-L197 PolarHBondContact O-N 3.14Å; Y193-L197 VanDerWaalsContact O-N 3.08Å; W194-L197 HydrophobicContact CE3-CD2 4.04Å; W194-L197 HydrophobicContact CZ3-CD2 3.98Å; W194-L197 PolarHBondContact O-N 3.28Å; L197-F200 PolarHBondContact O-N 2.91Å; L197-L201 WeakPolarHBondContact O-CB 3.19Å; L197-L201 PolarHBondContact O-N 2.98Å
198	T	97.6	Very high	93.8	Very high	5 Å²	5	55.5 Å²	55.5	3%	0.031	28%	0.277	C	S	.	.	H	α-helix	trans	-75.5	-30.6	-176.3	55.8	0	0	0	0	112.8	G160 F188 W194 P195 V196 L201 A202	G160-T198 WeakPolarHBondContact O-CB 3.27Å; G160-T198 PolarHBondContact O-OG1 2.89Å; F188-T198 HydrophobicContact CE2-CG2 4.45Å; W194-T198 HydrophobicContact CE3-CG2 4.09Å; W194-T198 WeakPolarHBondContact O-CB 3.31Å; W194-T198 WeakPolarHBondContact O-CG2 3.43Å; W194-T198 PolarHBondContact O-N 3.38Å; W194-T198 PolarHBondContact O-OG1 3.48Å; P195-T198 PolarHBondContact O-OG1 3.32Å; V196-T198 VanDerWaalsContact C-N 3.32Å; V196-T198 PolarHBondContact O-N 3.49Å; T198-L201 PolarHBondContact O-N 3.23Å; T198-A202 WeakPolarHBondContact O-CB 3.43Å; T198-A202 PolarHBondContact O-N 3.45Å
199	Q	97	Very high	94.1	Very high	0 Å²	0	57 Å²	57	0%	0	29%	0.288	C	S	.	.	H	α-helix	trans	-62.1	-48.9	168	-179.6	-153.5	-17.5	0	0	110.8	P156 V157 P195 V196 L201 A202 V203 A418 A425	P156-Q199 HydrophobicContact CB-CG 3.91Å; V157-Q199 HydrophobicContact CG2-CB 4.31Å; V157-Q199 HydrophobicContact CG2-CG 3.8Å; P195-Q199 WeakPolarHBondContact O-CB 3.27Å; P195-Q199 PolarHBondContact O-N 3.23Å; V196-Q199 PolarHBondContact O-N 3.18Å; Q199-L201 VanDerWaalsContact C-N 3.28Å; Q199-L201 PolarHBondContact O-N 3.44Å; Q199-A202 WeakPolarHBondContact O-CB 3.34Å; Q199-A202 PolarHBondContact O-N 2.98Å; Q199-A202 VanDerWaalsContact O-N 3.14Å; Q199-V203 WeakPolarHBondContact O-CG2 3.48Å; Q199-V203 PolarHBondContact O-N 3.12Å; Q199-A418 PolarHBondContact NE2-O 3.4Å; Q199-A425 VanDerWaalsContact OE1-CB 3.29Å
200	F	97.8	Very high	94.4	Very high	92 Å²	92	56.4 Å²	56.4	40%	0.404	28%	0.282	S	S	.	.	H	α-helix	trans	-61.4	-38.4	176.9	-88.7	-98.3	0	0	0	111.7	V196 L197 V203 A204 A418 V422	V196-F200 HydrophobicContact CG1-CD2 3.88Å; V196-F200 HydrophobicContact CG1-CE2 3.84Å; V196-F200 VanDerWaalsContact O-CD2 3.27Å; V196-F200 WeakPolarHBondContact O-CD2 3.37Å; V196-F200 PolarHBondContact O-N 3.09Å; L197-F200 PolarHBondContact O-N 2.91Å; F200-V203 PolarHBondContact O-N 3.41Å; F200-A204 WeakPolarHBondContact O-CB 3.42Å; F200-A204 PolarHBondContact O-N 2.85Å; F200-A418 HydrophobicContact CD1-CB 4.16Å; F200-A418 HydrophobicContact CE1-CB 3.81Å; F200-A418 HydrophobicContact CE2-CB 4.44Å; F200-A418 HydrophobicContact CZ-CB 3.98Å; F200-V422 HydrophobicContact CE2-CG2 3.92Å; F200-V422 HydrophobicContact CZ-CG2 4.41Å
201	L	97.5	Very high	94.9	Very high	78 Å²	78	52.4 Å²	52.4	41%	0.408	27%	0.27	S	S	.	.	H	α-helix	trans	-62.1	-44.7	172.8	-179.7	58.3	0	0	0	111.9	I163 L197 T198 Q199 V203 A204 L205	I163-L201 HydrophobicContact CG2-CD2 3.9Å; L197-L201 WeakPolarHBondContact O-CB 3.19Å; L197-L201 PolarHBondContact O-N 2.98Å; T198-L201 PolarHBondContact O-N 3.23Å; Q199-L201 VanDerWaalsContact C-N 3.28Å; Q199-L201 PolarHBondContact O-N 3.44Å; L201-V203 PolarHBondContact O-N 3.11Å; L201-A204 PolarHBondContact O-N 2.88Å; L201-L205 HydrophobicContact CD1-CD1 4.26Å; L201-L205 HydrophobicContact CD1-CG 4.15Å; L201-L205 HydrophobicContact CG-CD1 4.17Å; L201-L205 HydrophobicContact CG-CG 4.49Å; L201-L205 WeakPolarHBondContact O-CG 3.32Å; L201-L205 PolarHBondContact O-N 3.36Å
202	A	98	Very high	95.2	Very high	0 Å²	0	47.5 Å²	47.5	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-59.9	-44.5	176.9	0	0	0	0	0	112.3	P156 L159 I163 T198 Q199 T206	P156-A202 HydrophobicContact CB-CB 4.29Å; L159-A202 HydrophobicContact CB-CB 4.12Å; L159-A202 HydrophobicContact CD2-CB 3.85Å; L159-A202 HydrophobicContact CG-CB 3.74Å; I163-A202 HydrophobicContact CD1-CB 3.87Å; T198-A202 WeakPolarHBondContact O-CB 3.43Å; T198-A202 PolarHBondContact O-N 3.45Å; Q199-A202 WeakPolarHBondContact O-CB 3.34Å; Q199-A202 PolarHBondContact O-N 2.98Å; Q199-A202 VanDerWaalsContact O-N 3.14Å; A202-T206 WeakPolarHBondContact O-CB 3.36Å; A202-T206 PolarHBondContact O-N 3.23Å; A202-T206 VanDerWaalsContact O-N 3.09Å; A202-T206 PolarHBondContact O-OG1 3.07Å
203	V	97.8	Very high	95.4	Very high	10 Å²	10	46.1 Å²	46.1	6%	0.061	25%	0.246	C	C	.	.	H	α-helix	trans	-63.4	-44	175.3	173.5	0	0	0	0	110.8	P156 Q199 F200 L201 T206 G207 L414 A418	P156-V203 HydrophobicContact CB-CG2 3.74Å; P156-V203 HydrophobicContact CG-CG2 3.94Å; Q199-V203 WeakPolarHBondContact O-CG2 3.48Å; Q199-V203 PolarHBondContact O-N 3.12Å; F200-V203 PolarHBondContact O-N 3.41Å; L201-V203 PolarHBondContact O-N 3.11Å; V203-T206 PolarHBondContact O-N 2.9Å; V203-G207 PolarHBondContact O-N 3.35Å; V203-L414 HydrophobicContact CG1-CB 3.69Å; V203-L414 HydrophobicContact CG1-CD2 3.86Å; V203-L414 HydrophobicContact CG1-CG 4.29Å; V203-L414 WeakPolarHBondContact CG1-O 3.18Å; V203-A418 HydrophobicContact CG1-CB 4.28Å; V203-A418 HydrophobicContact CG2-CB 4.29Å
204	A	96.8	Very high	95.5	Very high	51 Å²	51	36.8 Å²	36.8	42%	0.421	21%	0.21	S	C	.	.	H	α-helix	trans	-63.6	-46.5	179.5	0	0	0	0	0	112.3	F200 L201 T206 G207 I208	F200-A204 WeakPolarHBondContact O-CB 3.42Å; F200-A204 PolarHBondContact O-N 2.85Å; L201-A204 PolarHBondContact O-N 2.88Å; A204-T206 VanDerWaalsContact C-N 3.32Å; A204-T206 PolarHBondContact O-N 3.13Å; A204-G207 PolarHBondContact O-N 3.04Å; A204-G207 VanDerWaalsContact O-N 3.15Å; A204-I208 WeakPolarHBondContact O-CG1 3.33Å; A204-I208 PolarHBondContact O-N 2.96Å
205	L	96.3	Very high	95.4	Very high	67 Å²	67	36.8 Å²	36.8	35%	0.351	21%	0.213	S	C	.	.	H	α-helix	trans	-59.7	-43.1	176.8	-71.7	174.3	0	0	0	111.7	I163 L201 I385	I163-L205 HydrophobicContact CD1-CD1 4.2Å; L201-L205 HydrophobicContact CD1-CD1 4.26Å; L201-L205 HydrophobicContact CD1-CG 4.15Å; L201-L205 HydrophobicContact CG-CD1 4.17Å; L201-L205 HydrophobicContact CG-CG 4.49Å; L201-L205 WeakPolarHBondContact O-CG 3.32Å; L201-L205 PolarHBondContact O-N 3.36Å; L205-I385 HydrophobicContact CB-CD1 4.45Å; L205-I385 HydrophobicContact CD1-CD1 4.42Å
206	T	96.1	Very high	95.4	Very high	0 Å²	0	42.7 Å²	42.7	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-63.6	-43.9	174.7	-57.6	0	0	0	0	110.9	A202 V203 A204 I208 C209 L210 L388 L389	A202-T206 WeakPolarHBondContact O-CB 3.36Å; A202-T206 PolarHBondContact O-N 3.23Å; A202-T206 VanDerWaalsContact O-N 3.09Å; A202-T206 PolarHBondContact O-OG1 3.07Å; V203-T206 PolarHBondContact O-N 2.9Å; A204-T206 VanDerWaalsContact C-N 3.32Å; A204-T206 PolarHBondContact O-N 3.13Å; T206-I208 VanDerWaalsContact C-N 3.33Å; T206-I208 PolarHBondContact O-N 3.35Å; T206-C209 PolarHBondContact O-N 3.26Å; T206-L210 WeakPolarHBondContact O-CB 3.45Å; T206-L210 PolarHBondContact O-N 3.22Å; T206-L388 HydrophobicContact CG2-CB 4.27Å; T206-L388 HydrophobicContact CG2-CD2 4.18Å; T206-L388 HydrophobicContact CG2-CG 3.9Å; T206-L388 WeakPolarHBondContact OG1-CD2 3.37Å; T206-L389 HydrophobicContact CG2-CD2 3.54Å; T206-L389 HydrophobicContact CG2-CG 3.91Å; T206-L389 VanDerWaalsContact O-CD2 3.22Å; T206-L389 WeakPolarHBondContact O-CD2 3.31Å
207	G	94.6	Very high	95.3	Very high	11 Å²	11	41.2 Å²	41.2	11%	0.113	23%	0.226	C	C	.	.	H	α-helix	trans	-62.3	-37.4	-178	0	0	0	0	0	114.4	V203 A204 C209 L210 A211	V203-G207 PolarHBondContact O-N 3.35Å; A204-G207 PolarHBondContact O-N 3.04Å; A204-G207 VanDerWaalsContact O-N 3.15Å; G207-C209 VanDerWaalsContact C-N 3.33Å; G207-C209 PolarHBondContact O-N 2.91Å; G207-L210 PolarHBondContact O-N 2.87Å; G207-A211 WeakPolarHBondContact O-CB 3.25Å; G207-A211 PolarHBondContact O-N 3.27Å
208	I	94	Very high	95.3	Very high	108 Å²	108	36.2 Å²	36.2	55%	0.554	20%	0.2	S	C	*	.	H	α-helix	trans	-57	-49.9	174.3	-68.2	164.1	0	0	0	109.8	A204 T206 L210 W216	A204-I208 WeakPolarHBondContact O-CG1 3.33Å; A204-I208 PolarHBondContact O-N 2.96Å; T206-I208 VanDerWaalsContact C-N 3.33Å; T206-I208 PolarHBondContact O-N 3.35Å; I208-L210 VanDerWaalsContact C-N 3.31Å; I208-L210 PolarHBondContact O-N 3.26Å; I208-W216 WeakPolarHBondContact O-CZ3 3.38Å
209	C	94.9	Very high	95.2	Very high	33 Å²	33	41.5 Å²	41.5	22%	0.223	22%	0.222	C	C	.	.	H	α-helix	trans	-69.3	-26.2	-179.5	-64.7	0	0	0	0	113.2	T206 G207 W216 A220 L389	T206-C209 PolarHBondContact O-N 3.26Å; G207-C209 VanDerWaalsContact C-N 3.33Å; G207-C209 PolarHBondContact O-N 2.91Å; C209-W216 CarbonylContact O-C 3.57Å; C209-W216 WeakPolarHBondContact O-CB 3.46Å; C209-A220 HydrophobicContact CB-CB 3.99Å; C209-L389 HydrophobicContact CB-CD1 3.99Å; C209-L389 HydrophobicContact CB-CD2 3.66Å; C209-L389 HydrophobicContact CB-CG 4.45Å
210	L	94.9	Very high	95.2	Very high	0 Å²	0	42.1 Å²	42.1	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-88.1	-24.5	-177	-170	58.6	0	0	0	114	T206 G207 I208 G212 G213 I217 L389 T392 Q393 V396 H406 V410	T206-L210 WeakPolarHBondContact O-CB 3.45Å; T206-L210 PolarHBondContact O-N 3.22Å; G207-L210 PolarHBondContact O-N 2.87Å; I208-L210 VanDerWaalsContact C-N 3.31Å; I208-L210 PolarHBondContact O-N 3.26Å; L210-G212 PolarHBondContact O-N 2.93Å; L210-G213 PolarHBondContact O-N 3.5Å; L210-I217 HydrophobicContact CD1-CD1 3.52Å; L210-I217 HydrophobicContact CD1-CG1 3.88Å; L210-L389 HydrophobicContact CB-CD2 3.91Å; L210-T392 HydrophobicContact CD2-CG2 3.43Å; L210-T392 VanDerWaalsContact CD2-CG2 3.43Å; L210-Q393 HydrophobicContact CD1-CB 4.16Å; L210-Q393 VanDerWaalsContact CD1-OE1 3.28Å; L210-V396 HydrophobicContact CD2-CG2 4.26Å; L210-H406 PolarHBondContact O-NE2 2.99Å; L210-H406 VanDerWaalsContact O-NE2 3.09Å; L210-V410 HydrophobicContact CB-CG1 4.3Å; L210-V410 HydrophobicContact CD2-CG1 4.16Å; L210-V410 HydrophobicContact CD2-CG2 4.18Å; L210-V410 HydrophobicContact CG-CG1 4.16Å; L210-V410 HydrophobicContact CG-CG2 3.87Å
211	A	93.4	Very high	95.2	Very high	36 Å²	36	37.7 Å²	37.7	30%	0.298	21%	0.208	S	C	.	.	T	Hydrogen-bonded Turn	trans	-59.5	-31.4	-173.2	0	0	0	0	0	114	G207 G213 H406	G207-A211 WeakPolarHBondContact O-CB 3.25Å; G207-A211 PolarHBondContact O-N 3.27Å; A211-G213 VanDerWaalsContact C-N 3.32Å; A211-H406 PolarHBondContact O-CD2 3.11Å
212	G	91.1	Very high	95.2	Very high	33 Å²	33	37.5 Å²	37.5	34%	0.34	21%	0.206	S	C	.	.	T	Hydrogen-bonded Turn	trans	-85.9	4.8	175.8	0	0	0	0	0	115.2	L210	L210-G212 PolarHBondContact O-N 2.93Å
213	G	92	Very high	95.2	Very high	5 Å²	5	43.1 Å²	43.1	5%	0.052	24%	0.235	C	C	.	.	T	Hydrogen-bonded Turn	trans	70.4	-157.4	-178.4	0	0	0	0	0	112.9	L210 A211 K215 W216 I217 H406	L210-G213 PolarHBondContact O-N 3.5Å; A211-G213 VanDerWaalsContact C-N 3.32Å; G213-K215 PolarHBondContact O-N 2.92Å; G213-K215 VanDerWaalsContact O-N 3.09Å; G213-W216 PolarHBondContact O-N 3.28Å; G213-I217 PolarHBondContact O-N 3.44Å; G213-I217 VanDerWaalsContact O-N 3.15Å; G213-H406 VanDerWaalsContact CA-CE1 3.47Å; G213-H406 WeakPolarHBondContact CA-CE1 3.46Å; G213-H406 VanDerWaalsContact CA-NE2 3.31Å; G213-H406 WeakPolarHBondContact CA-NE2 3.33Å; G213-H406 PolarHBondContact N-NE2 2.94Å
214	V	91.8	Very high	95.2	Very high	2 Å²	2	43.9 Å²	43.9	1%	0.012	24%	0.239	C	C	.	.	H	α-helix	trans	-57	-32.8	-169.9	77.7	0	0	0	0	113.6	S54 F56 W216 I217 E218 F290	S54-V214 WeakPolarHBondContact O-CG1 3.35Å; S54-V214 WeakPolarHBondContact OG-CG1 3.45Å; F56-V214 HydrophobicContact CD1-CG2 3.7Å; F56-V214 HydrophobicContact CE1-CG2 3.34Å; F56-V214 HydrophobicContact CE2-CG2 4.33Å; F56-V214 HydrophobicContact CG-CG2 4.33Å; F56-V214 HydrophobicContact CZ-CG2 3.7Å; V214-W216 VanDerWaalsContact C-N 3.29Å; V214-W216 PolarHBondContact O-N 2.83Å; V214-I217 PolarHBondContact O-N 3.16Å; V214-E218 WeakPolarHBondContact O-CB 3.42Å; V214-E218 PolarHBondContact O-N 3.4Å; V214-F290 HydrophobicContact CB-CD1 4.48Å; V214-F290 HydrophobicContact CB-CD2 4.35Å; V214-F290 HydrophobicContact CB-CE1 4.46Å; V214-F290 HydrophobicContact CB-CE2 4.38Å; V214-F290 HydrophobicContact CB-CG 4.4Å; V214-F290 HydrophobicContact CB-CZ 4.42Å; V214-F290 HydrophobicContact CG1-CD1 4.28Å; V214-F290 HydrophobicContact CG1-CG 4.43Å; V214-F290 HydrophobicContact CG2-CB 4.4Å; V214-F290 HydrophobicContact CG2-CD2 3.8Å; V214-F290 HydrophobicContact CG2-CE2 4.17Å; V214-F290 HydrophobicContact CG2-CG 4.03Å
215	K	92.2	Very high	95.3	Very high	101 Å²	101	41.6 Å²	41.6	44%	0.439	22%	0.22	S	C	.	.	H	α-helix	trans	-62.8	-33.9	177.4	-65.6	-175.1	179.6	-178.5	0	112.7	Q57 G213 K219	Q57-K215 HydrophobicContact CG-CG 4.33Å; G213-K215 PolarHBondContact O-N 2.92Å; G213-K215 VanDerWaalsContact O-N 3.09Å; K215-K219 VanDerWaalsContact O-CG 3.31Å; K215-K219 WeakPolarHBondContact O-CG 3.29Å; K215-K219 PolarHBondContact O-N 3.28Å
216	W	95.2	Very high	95.4	Very high	126 Å²	126	41.3 Å²	41.3	48%	0.477	22%	0.222	S	C	.	.	H	α-helix	trans	-85.8	-33.4	178.9	-75.6	33.5	0	0	0	111.7	I208 C209 G213 V214 E218 K219 A220	I208-W216 WeakPolarHBondContact O-CZ3 3.38Å; C209-W216 CarbonylContact O-C 3.57Å; C209-W216 WeakPolarHBondContact O-CB 3.46Å; G213-W216 PolarHBondContact O-N 3.28Å; V214-W216 VanDerWaalsContact C-N 3.29Å; V214-W216 PolarHBondContact O-N 2.83Å; W216-E218 VanDerWaalsContact C-N 3.31Å; W216-E218 PolarHBondContact O-N 3.21Å; W216-K219 PolarHBondContact O-N 3.41Å; W216-A220 WeakPolarHBondContact O-CB 3.36Å; W216-A220 PolarHBondContact O-N 3.49Å
217	I	95.6	Very high	95.5	Very high	0 Å²	0	44.3 Å²	44.3	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-56	-48.8	168.5	-62.1	175.6	0	0	0	109.9	L210 G213 V214 K219 A220 N221 Y287 Q393	L210-I217 HydrophobicContact CD1-CD1 3.52Å; L210-I217 HydrophobicContact CD1-CG1 3.88Å; G213-I217 PolarHBondContact O-N 3.44Å; G213-I217 VanDerWaalsContact O-N 3.15Å; V214-I217 PolarHBondContact O-N 3.16Å; I217-K219 PolarHBondContact O-N 3Å; I217-A220 PolarHBondContact O-N 2.93Å; I217-N221 WeakPolarHBondContact CG2-ND2 3.3Å; I217-N221 WeakPolarHBondContact O-CB 3.36Å; I217-N221 PolarHBondContact O-N 3.25Å; I217-N221 PolarHBondContact O-ND2 3.14Å; I217-Y287 VanDerWaalsContact CG2-OH 3.31Å; I217-Y287 WeakPolarHBondContact CG2-OH 3.43Å; I217-Q393 HydrophobicContact CD1-CB 4.11Å; I217-Q393 HydrophobicContact CD1-CG 3.87Å
218	E	96.2	Very high	95.7	Very high	2 Å²	2	43.8 Å²	43.8	1%	0.009	23%	0.232	C	C	.	.	H	α-helix	trans	-59	-48.4	177.8	179.2	175.7	177.3	0	0	111.7	F56 Q57 S58 G61 V214 W216 A220 N221 I222	F56-E218 WeakPolarHBondContact CA-OE2 3.14Å; F56-E218 HydrophobicContact CD1-CB 4.25Å; Q57-E218 WeakPolarHBondContact CB-OE2 3Å; Q57-E218 WeakPolarHBondContact CG-OE2 3.45Å; Q57-E218 PolarHBondContact N-OE1 3.18Å; Q57-E218 PolarHBondContact N-OE2 2.86Å; S58-E218 PolarHBondContact N-OE1 3.12Å; S58-E218 VanDerWaalsContact N-OE1 3.11Å; S58-E218 PolarHBondContact OG-OE1 3.35Å; G61-E218 WeakPolarHBondContact CA-OE1 3.42Å; V214-E218 WeakPolarHBondContact O-CB 3.42Å; V214-E218 PolarHBondContact O-N 3.4Å; W216-E218 VanDerWaalsContact C-N 3.31Å; W216-E218 PolarHBondContact O-N 3.21Å; E218-A220 VanDerWaalsContact C-N 3.32Å; E218-A220 PolarHBondContact O-N 3.18Å; E218-N221 PolarHBondContact O-N 3.02Å; E218-I222 HydrophobicContact CG-CD1 3.83Å; E218-I222 HydrophobicContact CG-CG1 4.4Å; E218-I222 WeakPolarHBondContact O-CB 3.44Å; E218-I222 VanDerWaalsContact O-CG1 3.31Å; E218-I222 WeakPolarHBondContact O-CG1 3.36Å; E218-I222 PolarHBondContact O-N 3.41Å
219	K	96.1	Very high	95.9	Very high	116 Å²	116	41 Å²	41	50%	0.504	22%	0.218	S	C	.	.	H	α-helix	trans	-59.3	-41.2	177.4	-74.8	177.7	-179.9	-168.1	0	112.7	K215 W216 I217	K215-K219 VanDerWaalsContact O-CG 3.31Å; K215-K219 WeakPolarHBondContact O-CG 3.29Å; K215-K219 PolarHBondContact O-N 3.28Å; W216-K219 PolarHBondContact O-N 3.41Å; I217-K219 PolarHBondContact O-N 3Å
220	A	97.3	Very high	96	Very high	13 Å²	13	45.9 Å²	45.9	11%	0.107	24%	0.236	C	C	.	.	H	α-helix	trans	-64.8	-48.7	175.9	0	0	0	0	0	110.8	C209 W216 I217 E218 I222 I223 L224 L389	C209-A220 HydrophobicContact CB-CB 3.99Å; W216-A220 WeakPolarHBondContact O-CB 3.36Å; W216-A220 PolarHBondContact O-N 3.49Å; I217-A220 PolarHBondContact O-N 2.93Å; E218-A220 VanDerWaalsContact C-N 3.32Å; E218-A220 PolarHBondContact O-N 3.18Å; A220-I222 PolarHBondContact O-N 2.69Å; A220-I223 PolarHBondContact O-N 3.08Å; A220-L224 HydrophobicContact CB-CD1 4.24Å; A220-L224 WeakPolarHBondContact O-CG 3.34Å; A220-L224 PolarHBondContact O-N 2.78Å; A220-L389 HydrophobicContact CB-CD1 4.16Å
221	N	98.1	Very high	96.2	Very high	0 Å²	0	46 Å²	46	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-68.6	-31.4	-176.7	-75	-27.4	0	0	0	113.4	I64 S65 I217 E218 I223 L224 V225 P226 S386	I64-N221 HydrophobicContact CG2-CB 4.17Å; I64-N221 VanDerWaalsContact CG2-O 3.25Å; I64-N221 WeakPolarHBondContact CG2-O 3.43Å; S65-N221 WeakPolarHBondContact CA-ND2 3.31Å; S65-N221 PolarHBondContact OG-ND2 3.16Å; I217-N221 WeakPolarHBondContact CG2-ND2 3.3Å; I217-N221 WeakPolarHBondContact O-CB 3.36Å; I217-N221 PolarHBondContact O-N 3.25Å; I217-N221 PolarHBondContact O-ND2 3.14Å; E218-N221 PolarHBondContact O-N 3.02Å; N221-I223 PolarHBondContact O-N 2.6Å; N221-I223 VanDerWaalsContact O-N 3.15Å; N221-L224 PolarHBondContact O-N 3.42Å; N221-V225 HydrophobicContact CB-CG2 4.19Å; N221-V225 WeakPolarHBondContact O-CB 3.47Å; N221-V225 PolarHBondContact O-N 3.1Å; N221-P226 WeakPolarHBondContact O-CD 3.39Å; N221-S386 VanDerWaalsContact OD1-CB 3.27Å; N221-S386 WeakPolarHBondContact OD1-CB 3.41Å
222	I	97.4	Very high	96.4	Very high	73 Å²	73	44.7 Å²	44.7	37%	0.374	23%	0.225	S	C	.	.	H	α-helix	trans	-58.2	-24.2	171.2	-76.9	172.2	0	0	0	112	I64 E218 A220 P226	I64-I222 HydrophobicContact CD1-CG1 4.49Å; E218-I222 HydrophobicContact CG-CD1 3.83Å; E218-I222 HydrophobicContact CG-CG1 4.4Å; E218-I222 WeakPolarHBondContact O-CB 3.44Å; E218-I222 VanDerWaalsContact O-CG1 3.31Å; E218-I222 WeakPolarHBondContact O-CG1 3.36Å; E218-I222 PolarHBondContact O-N 3.41Å; A220-I222 PolarHBondContact O-N 2.69Å; I222-P226 VanDerWaalsContact O-CD 3.26Å; I222-P226 WeakPolarHBondContact O-CD 3.39Å; I222-P226 VanDerWaalsContact O-CG 3.24Å; I222-P226 WeakPolarHBondContact O-CG 3.43Å
223	I	97.9	Very high	96.8	Very high	118 Å²	118	47.4 Å²	47.4	61%	0.605	23%	0.231	S	C	*	.	H	α-helix	trans	-97.6	-52.4	175.7	-59.4	172.7	0	0	0	110.8	A220 N221 V225 L227	A220-I223 PolarHBondContact O-N 3.08Å; N221-I223 PolarHBondContact O-N 2.6Å; N221-I223 VanDerWaalsContact O-N 3.15Å; I223-V225 PolarHBondContact O-N 2.66Å; I223-L227 VanDerWaalsContact O-CB 3.23Å; I223-L227 WeakPolarHBondContact O-CB 3.35Å; I223-L227 PolarHBondContact O-N 3.29Å
224	L	98.2	Very high	97.1	Very high	27 Å²	27	51 Å²	51	14%	0.141	25%	0.245	C	C	.	.	H	α-helix	trans	-63.3	-42.5	-172.1	-66.2	172.1	0	0	0	112.7	A220 N221 L228 C382 I385	A220-L224 HydrophobicContact CB-CD1 4.24Å; A220-L224 WeakPolarHBondContact O-CG 3.34Å; A220-L224 PolarHBondContact O-N 2.78Å; N221-L224 PolarHBondContact O-N 3.42Å; L224-L228 WeakPolarHBondContact O-CB 3.26Å; L224-L228 PolarHBondContact O-N 3.04Å; L224-C382 HydrophobicContact CD2-CB 4.26Å; L224-I385 HydrophobicContact CD1-CB 4.18Å; L224-I385 HydrophobicContact CD1-CG2 3.73Å
225	V	98.3	Very high	97.4	Very high	3 Å²	3	51.2 Å²	51.2	2%	0.018	25%	0.246	C	C	.	.	H	α-helix	trans	-75.4	-46.3	-173.7	177.3	0	0	0	0	112.1	I64 V67 G68 N221 I223 L227 L228 L229	I64-V225 HydrophobicContact CG2-CB 3.77Å; I64-V225 HydrophobicContact CG2-CG1 4.15Å; I64-V225 HydrophobicContact CG2-CG2 4.08Å; V67-V225 HydrophobicContact CB-CG1 4.19Å; V67-V225 HydrophobicContact CG1-CG1 3.68Å; G68-V225 VanDerWaalsContact CA-CG2 3.46Å; N221-V225 HydrophobicContact CB-CG2 4.19Å; N221-V225 WeakPolarHBondContact O-CB 3.47Å; N221-V225 PolarHBondContact O-N 3.1Å; I223-V225 PolarHBondContact O-N 2.66Å; V225-L227 VanDerWaalsContact C-N 3.28Å; V225-L227 PolarHBondContact O-N 3.35Å; V225-L228 HydrophobicContact CB-CD2 4.45Å; V225-L228 HydrophobicContact CG2-CD2 4.36Å; V225-L228 WeakPolarHBondContact O-CG 3.39Å; V225-L228 PolarHBondContact O-N 3.24Å; V225-L229 HydrophobicContact CG1-CD1 4.04Å; V225-L229 HydrophobicContact CG1-CG 4.41Å; V225-L229 WeakPolarHBondContact O-CB 3.4Å; V225-L229 VanDerWaalsContact O-CG 3.26Å; V225-L229 WeakPolarHBondContact O-CG 3.27Å; V225-L229 PolarHBondContact O-N 3.01Å
226	P	98.3	Very high	97.7	Very high	60 Å²	60	48.5 Å²	48.5	39%	0.39	23%	0.234	S	C	.	.	H	α-helix	trans	-60.5	-38.2	171.9	-28.2	39.5	0	0	0	112.8	N221 I222 L229 F230	N221-P226 WeakPolarHBondContact O-CD 3.39Å; I222-P226 VanDerWaalsContact O-CD 3.26Å; I222-P226 WeakPolarHBondContact O-CD 3.39Å; I222-P226 VanDerWaalsContact O-CG 3.24Å; I222-P226 WeakPolarHBondContact O-CG 3.43Å; P226-L229 PolarHBondContact O-N 3.49Å; P226-F230 VanDerWaalsContact O-CB 3.28Å; P226-F230 WeakPolarHBondContact O-CB 3.35Å; P226-F230 PolarHBondContact O-N 2.89Å
227	L	98.5	Very high	97.8	Very high	64 Å²	64	44 Å²	44	34%	0.335	23%	0.227	S	C	.	.	H	α-helix	trans	-63.1	-48.3	177.2	178.9	59.7	0	0	0	112	I223 V225 L229 F230 I231	I223-L227 VanDerWaalsContact O-CB 3.23Å; I223-L227 WeakPolarHBondContact O-CB 3.35Å; I223-L227 PolarHBondContact O-N 3.29Å; V225-L227 VanDerWaalsContact C-N 3.28Å; V225-L227 PolarHBondContact O-N 3.35Å; L227-L229 VanDerWaalsContact C-N 3.33Å; L227-L229 PolarHBondContact O-N 3.39Å; L227-F230 PolarHBondContact O-N 3.07Å; L227-I231 HydrophobicContact CD1-CD1 3.96Å; L227-I231 HydrophobicContact CD1-CG1 4.26Å; L227-I231 HydrophobicContact CG-CD1 4.02Å; L227-I231 VanDerWaalsContact O-CG1 3.29Å; L227-I231 WeakPolarHBondContact O-CG1 3.13Å; L227-I231 PolarHBondContact O-N 2.9Å
228	L	97.9	Very high	98	Very high	0 Å²	0	45 Å²	45	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-63	-41.6	179.3	79.6	85.5	0	0	0	111.2	V71 L224 V225 I231 I232 C382 A383	V71-L228 HydrophobicContact CG1-CD1 3.81Å; L224-L228 WeakPolarHBondContact O-CB 3.26Å; L224-L228 PolarHBondContact O-N 3.04Å; V225-L228 HydrophobicContact CB-CD2 4.45Å; V225-L228 HydrophobicContact CG2-CD2 4.36Å; V225-L228 WeakPolarHBondContact O-CG 3.39Å; V225-L228 PolarHBondContact O-N 3.24Å; L228-I231 PolarHBondContact O-N 2.95Å; L228-I232 HydrophobicContact CD1-CD1 4.49Å; L228-I232 WeakPolarHBondContact O-CG1 3.42Å; L228-I232 PolarHBondContact O-N 2.91Å; L228-C382 HydrophobicContact CB-CB 3.84Å; L228-A383 HydrophobicContact CD2-CB 4.27Å
229	L	98.2	Very high	98.1	Very high	49 Å²	49	44.9 Å²	44.9	26%	0.257	23%	0.23	S	C	.	.	H	α-helix	trans	-65.6	-42.9	179.3	-69.3	176.4	0	0	0	111.1	V225 P226 L227 I231 I232 L233 V311	V225-L229 HydrophobicContact CG1-CD1 4.04Å; V225-L229 HydrophobicContact CG1-CG 4.41Å; V225-L229 WeakPolarHBondContact O-CB 3.4Å; V225-L229 VanDerWaalsContact O-CG 3.26Å; V225-L229 WeakPolarHBondContact O-CG 3.27Å; V225-L229 PolarHBondContact O-N 3.01Å; P226-L229 PolarHBondContact O-N 3.49Å; L227-L229 VanDerWaalsContact C-N 3.33Å; L227-L229 PolarHBondContact O-N 3.39Å; L229-I231 VanDerWaalsContact C-N 3.35Å; L229-I231 PolarHBondContact O-N 3.14Å; L229-I232 PolarHBondContact O-N 3.37Å; L229-L233 WeakPolarHBondContact O-CB 3.39Å; L229-L233 VanDerWaalsContact O-CG 3.27Å; L229-L233 WeakPolarHBondContact O-CG 3.49Å; L229-L233 PolarHBondContact O-N 3.15Å; L229-V311 HydrophobicContact CD2-CG2 3.52Å
230	F	98.5	Very high	98.1	Very high	136 Å²	136	42.7 Å²	42.7	60%	0.596	22%	0.223	S	C	*	.	H	α-helix	trans	-58	-47.3	174.6	173.8	-98.1	0	0	0	111.6	P226 L227 I232 L233 F234	P226-F230 VanDerWaalsContact O-CB 3.28Å; P226-F230 WeakPolarHBondContact O-CB 3.35Å; P226-F230 PolarHBondContact O-N 2.89Å; L227-F230 PolarHBondContact O-N 3.07Å; F230-I232 PolarHBondContact O-N 3.29Å; F230-L233 PolarHBondContact O-N 3.39Å; F230-F234 WeakPolarHBondContact O-CB 3.5Å; F230-F234 PolarHBondContact O-N 3.44Å
231	I	98.6	Very high	98.2	Very high	2 Å²	2	46.3 Å²	46.3	1%	0.01	24%	0.244	C	C	.	.	H	α-helix	trans	-62.3	-45.8	179.7	-65.7	166.7	0	0	0	111.1	L227 L228 L229 L233 F234 M235 L375 L378 C379	L227-I231 HydrophobicContact CD1-CD1 3.96Å; L227-I231 HydrophobicContact CD1-CG1 4.26Å; L227-I231 HydrophobicContact CG-CD1 4.02Å; L227-I231 VanDerWaalsContact O-CG1 3.29Å; L227-I231 WeakPolarHBondContact O-CG1 3.13Å; L227-I231 PolarHBondContact O-N 2.9Å; L228-I231 PolarHBondContact O-N 2.95Å; L229-I231 VanDerWaalsContact C-N 3.35Å; L229-I231 PolarHBondContact O-N 3.14Å; I231-L233 VanDerWaalsContact C-N 3.34Å; I231-L233 PolarHBondContact O-N 2.99Å; I231-F234 PolarHBondContact O-N 3.31Å; I231-M235 HydrophobicContact CG2-CG 4.19Å; I231-M235 HydrophobicContact CG2-SD 4.02Å; I231-M235 WeakPolarHBondContact O-CB 3.48Å; I231-M235 VanDerWaalsContact O-CG 3.31Å; I231-M235 WeakPolarHBondContact O-CG 3.34Å; I231-M235 PolarHBondContact O-N 3Å; I231-L375 HydrophobicContact CD1-CD2 4.42Å; I231-L375 HydrophobicContact CG1-CD2 4.29Å; I231-L375 HydrophobicContact CG2-CB 3.94Å; I231-L375 WeakPolarHBondContact CG2-O 3.3Å; I231-L378 HydrophobicContact CD1-CB 4.38Å; I231-L378 HydrophobicContact CD1-CD2 3.99Å; I231-L378 HydrophobicContact CD1-CG 4.05Å; I231-C379 HydrophobicContact CB-CB 4.13Å; I231-C379 HydrophobicContact CD1-CB 4.33Å; I231-C379 HydrophobicContact CG2-CB 3.72Å
232	I	98.1	Very high	98.1	Very high	9 Å²	9	50 Å²	50	5%	0.046	26%	0.258	C	S	.	.	H	α-helix	trans	-60.7	-45	178.5	-71.1	-175.2	0	0	0	111.2	I76 L228 L229 F230 M235 F236 V311 C379	I76-I232 HydrophobicContact CD1-CD1 3.84Å; I76-I232 HydrophobicContact CG1-CD1 3.76Å; L228-I232 HydrophobicContact CD1-CD1 4.49Å; L228-I232 WeakPolarHBondContact O-CG1 3.42Å; L228-I232 PolarHBondContact O-N 2.91Å; L229-I232 PolarHBondContact O-N 3.37Å; F230-I232 PolarHBondContact O-N 3.29Å; I232-M235 PolarHBondContact O-N 3.49Å; I232-F236 WeakPolarHBondContact O-CB 3.42Å; I232-F236 PolarHBondContact O-N 2.98Å; I232-V311 HydrophobicContact CD1-CG1 3.43Å; I232-V311 VanDerWaalsContact CD1-CG1 3.43Å; I232-C379 WeakPolarHBondContact CG1-SG 3.43Å
233	L	98.4	Very high	98	Very high	90 Å²	90	52.1 Å²	52.1	47%	0.471	27%	0.266	S	S	.	.	H	α-helix	trans	-66.1	-40	179.7	-69.2	174.5	0	0	0	112	L229 F230 I231 F236 G237 Y314	L229-L233 WeakPolarHBondContact O-CB 3.39Å; L229-L233 VanDerWaalsContact O-CG 3.27Å; L229-L233 WeakPolarHBondContact O-CG 3.49Å; L229-L233 PolarHBondContact O-N 3.15Å; F230-L233 PolarHBondContact O-N 3.39Å; I231-L233 VanDerWaalsContact C-N 3.34Å; I231-L233 PolarHBondContact O-N 2.99Å; L233-F236 PolarHBondContact O-N 3.22Å; L233-G237 PolarHBondContact O-N 3.46Å; L233-Y314 HydrophobicContact CD2-CD2 3.92Å; L233-Y314 HydrophobicContact CD2-CE2 3.79Å
234	F	98.6	Very high	97.9	Very high	81 Å²	81	50.2 Å²	50.2	36%	0.355	25%	0.252	S	S	.	.	H	α-helix	trans	-61.2	-49.8	174	170.8	-99.5	0	0	0	111.6	F230 I231 F236 G237 W238 F368 L372 L375	F230-F234 WeakPolarHBondContact O-CB 3.5Å; F230-F234 PolarHBondContact O-N 3.44Å; I231-F234 PolarHBondContact O-N 3.31Å; F234-F236 VanDerWaalsContact C-N 3.35Å; F234-F236 PolarHBondContact O-N 2.83Å; F234-G237 PolarHBondContact O-N 2.83Å; F234-W238 WeakPolarHBondContact O-CB 3.44Å; F234-W238 PolarHBondContact O-N 3.2Å; F234-F368 HydrophobicContact CZ-CZ 4.13Å; F234-L372 HydrophobicContact CE1-CD2 3.91Å; F234-L375 HydrophobicContact CD1-CD1 3.96Å; F234-L375 HydrophobicContact CE1-CD1 3.68Å
235	M	98.1	Very high	97.9	Very high	6 Å²	6	49 Å²	49	3%	0.03	25%	0.246	C	C	.	.	H	α-helix	trans	-64	-40.3	179.1	-73	-170.2	70.8	0	0	112.2	I231 I232 W238 A239 T318 F362 F376	I231-M235 HydrophobicContact CG2-CG 4.19Å; I231-M235 HydrophobicContact CG2-SD 4.02Å; I231-M235 WeakPolarHBondContact O-CB 3.48Å; I231-M235 VanDerWaalsContact O-CG 3.31Å; I231-M235 WeakPolarHBondContact O-CG 3.34Å; I231-M235 PolarHBondContact O-N 3Å; I232-M235 PolarHBondContact O-N 3.49Å; M235-W238 PolarHBondContact O-N 3.39Å; M235-A239 VanDerWaalsContact O-CB 3.26Å; M235-A239 WeakPolarHBondContact O-CB 3.46Å; M235-A239 PolarHBondContact O-N 3.02Å; M235-T318 HydrophobicContact CB-CG2 3.99Å; M235-T318 HydrophobicContact CE-CG2 4.37Å; M235-F362 HydrophobicContact CE-CE1 4.4Å; M235-F362 HydrophobicContact CE-CE2 4.06Å; M235-F362 HydrophobicContact CE-CZ 3.47Å; M235-F362 VanDerWaalsContact CE-CZ 3.47Å; M235-F376 HydrophobicContact CE-CB 3.73Å; M235-F376 HydrophobicContact CE-CD2 3.71Å; M235-F376 HydrophobicContact CE-CG 4.13Å; M235-F376 HydrophobicContact SD-CB 3.86Å; M235-F376 HydrophobicContact SD-CD2 4.03Å; M235-F376 HydrophobicContact SD-CG 4.46Å
236	F	98.4	Very high	97.8	Very high	43 Å²	43	53.5 Å²	53.5	19%	0.189	27%	0.267	C	S	.	.	H	α-helix	trans	-59.4	-52.3	174	170.5	-99.7	0	0	0	111.1	I232 L233 F234 W238 A239 I240 Y314 I317 T318	I232-F236 WeakPolarHBondContact O-CB 3.42Å; I232-F236 PolarHBondContact O-N 2.98Å; L233-F236 PolarHBondContact O-N 3.22Å; F234-F236 VanDerWaalsContact C-N 3.35Å; F234-F236 PolarHBondContact O-N 2.83Å; F236-W238 VanDerWaalsContact C-N 3.27Å; F236-W238 PolarHBondContact O-N 3.16Å; F236-A239 PolarHBondContact O-N 3.39Å; F236-A239 VanDerWaalsContact O-N 3.14Å; F236-I240 HydrophobicContact CD2-CG2 4.21Å; F236-I240 HydrophobicContact CE1-CD1 4.12Å; F236-I240 HydrophobicContact CE2-CG2 3.86Å; F236-I240 HydrophobicContact CZ-CD1 4.35Å; F236-I240 HydrophobicContact CZ-CG2 4.07Å; F236-I240 WeakPolarHBondContact O-CG1 3.41Å; F236-I240 WeakPolarHBondContact O-CG2 3.33Å; F236-I240 PolarHBondContact O-N 3.21Å; F236-I240 VanDerWaalsContact O-N 3.1Å; F236-Y314 HydrophobicContact CD1-CD1 4.37Å; F236-Y314 AromaticContact CD2-CD1 3.86Å; F236-Y314 HydrophobicContact CD2-CD1 3.86Å; F236-Y314 HydrophobicContact CD2-CG 4.32Å; F236-Y314 HydrophobicContact CE1-CD1 4.25Å; F236-Y314 HydrophobicContact CE1-CE1 4.27Å; F236-Y314 AromaticContact CE2-CD1 3.71Å; F236-Y314 HydrophobicContact CE2-CD1 3.71Å; F236-Y314 HydrophobicContact CE2-CE1 4.32Å; F236-Y314 HydrophobicContact CG-CD1 4.19Å; F236-Y314 HydrophobicContact CG-CG 4.42Å; F236-Y314 AromaticContact CZ-CD1 3.93Å; F236-Y314 HydrophobicContact CZ-CD1 3.93Å; F236-Y314 HydrophobicContact CZ-CE1 4.08Å; F236-I317 HydrophobicContact CD2-CB 4.18Å; F236-I317 HydrophobicContact CD2-CG2 4.05Å; F236-I317 HydrophobicContact CE2-CB 3.88Å; F236-I317 HydrophobicContact CE2-CD1 3.95Å; F236-I317 HydrophobicContact CE2-CG2 3.58Å; F236-T318 VanDerWaalsContact CA-OG1 3.23Å; F236-T318 WeakPolarHBondContact CA-OG1 3.4Å; F236-T318 WeakPolarHBondContact CB-OG1 3.39Å
237	G	98.4	Very high	97.7	Very high	31 Å²	31	52.5 Å²	52.5	32%	0.32	26%	0.257	S	S	.	.	H	α-helix	trans	-58.4	-39	177.3	0	0	0	0	0	112.5	L233 F234 I240 T241	L233-G237 PolarHBondContact O-N 3.46Å; F234-G237 PolarHBondContact O-N 2.83Å; G237-I240 WeakPolarHBondContact O-CG1 3.2Å; G237-T241 WeakPolarHBondContact O-CG2 3.36Å
238	W	98	Very high	97.6	Very high	21 Å²	21	49.4 Å²	49.4	8%	0.08	24%	0.242	C	C	.	.	H	α-helix	trans	-66.3	-47.3	173.4	170.9	78.7	0	0	0	112.6	F234 M235 F236 I240 T241 R242 T322 F362 F365 F368 L372	F234-W238 WeakPolarHBondContact O-CB 3.44Å; F234-W238 PolarHBondContact O-N 3.2Å; M235-W238 PolarHBondContact O-N 3.39Å; F236-W238 VanDerWaalsContact C-N 3.27Å; F236-W238 PolarHBondContact O-N 3.16Å; W238-I240 PolarHBondContact O-N 2.65Å; W238-T241 PolarHBondContact O-N 3.34Å; W238-T241 PolarHBondContact O-OG1 3.31Å; W238-R242 HydrophobicContact CH2-CG 4.36Å; W238-R242 HydrophobicContact CZ2-CG 4.21Å; W238-R242 PolarHBondContact O-NE 3.18Å; W238-T322 HydrophobicContact CH2-CG2 4.19Å; W238-T322 HydrophobicContact CZ3-CG2 4.13Å; W238-F362 HydrophobicContact CH2-CD1 4.25Å; W238-F362 AromaticContact CH2-CE1 3.87Å; W238-F362 HydrophobicContact CH2-CE1 3.87Å; W238-F362 AromaticContact CZ3-CE1 3.72Å; W238-F362 HydrophobicContact CZ3-CE1 3.72Å; W238-F365 HydrophobicContact CH2-CD2 4.19Å; W238-F365 HydrophobicContact CH2-CE1 4.47Å; W238-F365 AromaticContact CH2-CE2 3.87Å; W238-F365 HydrophobicContact CH2-CE2 3.87Å; W238-F365 HydrophobicContact CH2-CZ 4.01Å; W238-F365 HydrophobicContact CZ2-CD1 4.08Å; W238-F365 HydrophobicContact CZ2-CD2 4.19Å; W238-F365 AromaticContact CZ2-CE1 4Å; W238-F365 HydrophobicContact CZ2-CE1 4Å; W238-F365 HydrophobicContact CZ2-CE2 4.11Å; W238-F365 HydrophobicContact CZ2-CG 4.17Å; W238-F365 HydrophobicContact CZ2-CZ 4.01Å; W238-F368 AromaticContact CD1-CE1 3.6Å; W238-F368 HydrophobicContact CG-CE1 4.31Å; W238-F368 AromaticContact NE1-CE1 3.4Å; W238-L372 HydrophobicContact CD2-CD1 3.78Å; W238-L372 HydrophobicContact CD2-CD2 4.12Å; W238-L372 VanDerWaalsContact CE2-CD1 3.42Å; W238-L372 HydrophobicContact CE3-CD1 3.96Å; W238-L372 HydrophobicContact CE3-CD2 4.28Å; W238-L372 HydrophobicContact CG-CD2 4.35Å; W238-L372 HydrophobicContact CH2-CD1 3.49Å; W238-L372 VanDerWaalsContact CH2-CD1 3.49Å; W238-L372 HydrophobicContact CZ2-CD1 3.25Å; W238-L372 HydrophobicContact CZ3-CD1 3.85Å
239	A	98.1	Very high	97.6	Very high	0 Å²	0	51.8 Å²	51.8	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-65.4	-38.5	-172.8	0	0	0	0	0	112.7	M235 F236 T241 R242 A245 T318	M235-A239 VanDerWaalsContact O-CB 3.26Å; M235-A239 WeakPolarHBondContact O-CB 3.46Å; M235-A239 PolarHBondContact O-N 3.02Å; F236-A239 PolarHBondContact O-N 3.39Å; F236-A239 VanDerWaalsContact O-N 3.14Å; A239-T241 PolarHBondContact O-N 3Å; A239-R242 WeakPolarHBondContact O-CB 3.28Å; A239-R242 WeakPolarHBondContact O-CG 3.27Å; A239-R242 PolarHBondContact O-N 2.93Å; A239-A245 WeakPolarHBondContact O-CB 2.96Å; A239-T318 HydrophobicContact CB-CG2 3.86Å
240	I	98.1	Very high	97.5	Very high	70 Å²	70	53.2 Å²	53.2	36%	0.359	26%	0.264	S	S	.	.	H	α-helix	trans	-70.4	-16.1	179.5	66.2	175.4	0	0	0	113.6	F236 G237 W238 R242 I249 I317	F236-I240 HydrophobicContact CD2-CG2 4.21Å; F236-I240 HydrophobicContact CE1-CD1 4.12Å; F236-I240 HydrophobicContact CE2-CG2 3.86Å; F236-I240 HydrophobicContact CZ-CD1 4.35Å; F236-I240 HydrophobicContact CZ-CG2 4.07Å; F236-I240 WeakPolarHBondContact O-CG1 3.41Å; F236-I240 WeakPolarHBondContact O-CG2 3.33Å; F236-I240 PolarHBondContact O-N 3.21Å; F236-I240 VanDerWaalsContact O-N 3.1Å; G237-I240 WeakPolarHBondContact O-CG1 3.2Å; W238-I240 PolarHBondContact O-N 2.65Å; I240-R242 VanDerWaalsContact C-N 3.34Å; I240-I249 HydrophobicContact CB-CD1 4.45Å; I240-I249 HydrophobicContact CG2-CD1 4.16Å; I240-I317 HydrophobicContact CG2-CG2 3.98Å
241	T	97.5	Very high	97.4	Very high	90 Å²	90	47.1 Å²	47.1	55%	0.552	24%	0.238	S	C	*	.	T	Hydrogen-bonded Turn	trans	-89.1	-1.6	177.1	65.4	0	0	0	0	113.2	G237 W238 A239	G237-T241 WeakPolarHBondContact O-CG2 3.36Å; W238-T241 PolarHBondContact O-N 3.34Å; W238-T241 PolarHBondContact O-OG1 3.31Å; A239-T241 PolarHBondContact O-N 3Å
242	R	96.5	Very high	97.3	Very high	78 Å²	78	47 Å²	47	29%	0.294	24%	0.237	S	C	.	.	S	Bend	trans	-77.8	143.4	-178.6	-56.5	-60.2	91.2	-168.4	-1.2	110.6	W238 A239 I240 Y244 A245 S325	W238-R242 HydrophobicContact CH2-CG 4.36Å; W238-R242 HydrophobicContact CZ2-CG 4.21Å; W238-R242 PolarHBondContact O-NE 3.18Å; A239-R242 WeakPolarHBondContact O-CB 3.28Å; A239-R242 WeakPolarHBondContact O-CG 3.27Å; A239-R242 PolarHBondContact O-N 2.93Å; I240-R242 VanDerWaalsContact C-N 3.34Å; R242-Y244 PolarHBondContact O-N 3.43Å; R242-A245 HydrophobicContact CB-CB 4.34Å; R242-A245 WeakPolarHBondContact O-CB 3.26Å; R242-A245 PolarHBondContact O-N 3.01Å; R242-S325 VanDerWaalsContact CB-OG 3.26Å; R242-S325 WeakPolarHBondContact CB-OG 3.44Å
243	Q	96.4	Very high	97.3	Very high	116 Å²	116	51.3 Å²	51.3	54%	0.542	26%	0.256	S	S	.	.	T	Hydrogen-bonded Turn	trans	-58.6	135.3	174.2	-170.5	-178.2	-3.9	0	0	110.2	A245 S325	Q243-A245 PolarHBondContact O-N 3.05Å; Q243-S325 WeakPolarHBondContact O-CA 3.22Å; Q243-S325 WeakPolarHBondContact O-CB 3.4Å; Q243-S325 PolarHBondContact O-OG 3.16Å
244	Y	95.9	Very high	97.2	Very high	78 Å²	78	49.2 Å²	49.2	31%	0.306	25%	0.247	S	C	.	.	T	Hydrogen-bonded Turn	trans	70.4	4.3	-175	-45.8	-67.4	0	0	0	115.6	R242 E246 I247 I328 Q329	R242-Y244 PolarHBondContact O-N 3.43Å; Y244-E246 WeakPolarHBondContact CA-OE1 3.41Å; Y244-E246 WeakPolarHBondContact CA-OE2 3.4Å; Y244-E246 PolarHBondContact N-OE2 3.09Å; Y244-E246 VanDerWaalsContact N-OE2 3.12Å; Y244-E246 PolarHBondContact O-N 3.45Å; Y244-I247 HydrophobicContact CD1-CD1 3.93Å; Y244-I247 HydrophobicContact CG-CD1 4.45Å; Y244-I247 WeakPolarHBondContact O-CB 3.14Å; Y244-I247 PolarHBondContact O-N 3.34Å; Y244-I247 VanDerWaalsContact O-N 3.14Å; Y244-I328 HydrophobicContact CD1-CG2 4.12Å; Y244-I328 HydrophobicContact CD2-CB 4.15Å; Y244-I328 HydrophobicContact CD2-CG2 3.69Å; Y244-I328 HydrophobicContact CE1-CG2 4.29Å; Y244-I328 HydrophobicContact CE2-CG2 3.89Å; Y244-I328 HydrophobicContact CG-CB 4.3Å; Y244-I328 HydrophobicContact CG-CG2 3.81Å; Y244-Q329 HydrophobicContact CD2-CG 3.93Å; Y244-Q329 HydrophobicContact CE2-CG 3.93Å
245	A	97.3	Very high	96.9	Very high	1 Å²	1	47.6 Å²	47.6	1%	0.008	25%	0.245	C	C	.	.	H	α-helix	trans	-59.7	-33.5	172.8	0	0	0	0	0	111.8	A239 R242 Q243 I247 G248 I249	A239-A245 WeakPolarHBondContact O-CB 2.96Å; R242-A245 HydrophobicContact CB-CB 4.34Å; R242-A245 WeakPolarHBondContact O-CB 3.26Å; R242-A245 PolarHBondContact O-N 3.01Å; Q243-A245 PolarHBondContact O-N 3.05Å; A245-I247 PolarHBondContact O-N 2.95Å; A245-G248 PolarHBondContact O-N 3.34Å; A245-G248 VanDerWaalsContact O-N 3.14Å; A245-I249 WeakPolarHBondContact O-CG1 3.44Å; A245-I249 PolarHBondContact O-N 3.01Å
246	E	97	Very high	96.5	Very high	99 Å²	99	48 Å²	48	46%	0.463	25%	0.248	S	C	.	.	H	α-helix	trans	-59.6	-28.4	177.3	72.4	-72.9	172.3	0	0	112.6	Y244 T250	Y244-E246 WeakPolarHBondContact CA-OE1 3.41Å; Y244-E246 WeakPolarHBondContact CA-OE2 3.4Å; Y244-E246 PolarHBondContact N-OE2 3.09Å; Y244-E246 VanDerWaalsContact N-OE2 3.12Å; Y244-E246 PolarHBondContact O-N 3.45Å; E246-T250 WeakPolarHBondContact O-CB 3.42Å; E246-T250 PolarHBondContact O-N 3.32Å; E246-T250 PolarHBondContact O-OG1 2.88Å
247	I	95.6	Very high	96.2	Very high	38 Å²	38	53.5 Å²	53.5	20%	0.195	27%	0.267	C	S	.	.	H	α-helix	trans	-70.7	-43	177.4	-57.4	179.1	0	0	0	110.1	Y244 A245 T250 F251 F324 I328 R336	Y244-I247 HydrophobicContact CD1-CD1 3.93Å; Y244-I247 HydrophobicContact CG-CD1 4.45Å; Y244-I247 WeakPolarHBondContact O-CB 3.14Å; Y244-I247 PolarHBondContact O-N 3.34Å; Y244-I247 VanDerWaalsContact O-N 3.14Å; A245-I247 PolarHBondContact O-N 2.95Å; I247-T250 PolarHBondContact O-N 3.09Å; I247-F251 PolarHBondContact O-N 3.15Å; I247-F324 HydrophobicContact CB-CD1 4.15Å; I247-F324 HydrophobicContact CG2-CD1 3.68Å; I247-F324 HydrophobicContact CG2-CE1 3.91Å; I247-I328 HydrophobicContact CB-CD1 4.49Å; I247-I328 HydrophobicContact CD1-CD1 3.76Å; I247-I328 HydrophobicContact CG2-CD1 4.44Å; I247-R336 HydrophobicContact CG2-CG 4.18Å
248	G	96.1	Very high	95.7	Very high	0 Å²	0	56.4 Å²	56.4	0%	0	28%	0.283	C	S	.	.	H	α-helix	trans	-65.6	-43.4	175.1	0	0	0	0	0	112.2	A245 F251 L252	A245-G248 PolarHBondContact O-N 3.34Å; A245-G248 VanDerWaalsContact O-N 3.14Å; G248-F251 WeakPolarHBondContact O-CB 3.2Å; G248-F251 PolarHBondContact O-N 2.97Å; G248-L252 WeakPolarHBondContact O-CG 3.5Å; G248-L252 PolarHBondContact O-N 3.39Å
249	I	97.5	Very high	95.2	Very high	49 Å²	49	56.1 Å²	56.1	25%	0.251	28%	0.284	S	S	.	.	H	α-helix	trans	-62.5	-46.1	174.9	-63.7	165.1	0	0	0	110.3	I240 A245 F251 L252 F253 I317 S321	I240-I249 HydrophobicContact CB-CD1 4.45Å; I240-I249 HydrophobicContact CG2-CD1 4.16Å; A245-I249 WeakPolarHBondContact O-CG1 3.44Å; A245-I249 PolarHBondContact O-N 3.01Å; I249-F251 VanDerWaalsContact C-N 3.28Å; I249-F251 PolarHBondContact O-N 3.35Å; I249-L252 WeakPolarHBondContact O-CB 3.41Å; I249-L252 PolarHBondContact O-N 2.8Å; I249-L252 VanDerWaalsContact O-N 3.12Å; I249-F253 HydrophobicContact CG2-CD2 3.89Å; I249-F253 HydrophobicContact CG2-CE2 4.19Å; I249-F253 WeakPolarHBondContact O-CD2 3.34Å; I249-F253 PolarHBondContact O-N 3.38Å; I249-I317 HydrophobicContact CD1-CG2 4.49Å; I249-I317 HydrophobicContact CG1-CG2 4.04Å; I249-S321 WeakPolarHBondContact CG1-OG 3.35Å
250	T	96.9	Very high	94.8	Very high	79 Å²	79	59.5 Å²	59.5	49%	0.485	30%	0.298	S	S	.	.	H	α-helix	trans	-57.4	-43.7	176.7	-61	0	0	0	0	110.7	E246 I247 L252 F253 T254	E246-T250 WeakPolarHBondContact O-CB 3.42Å; E246-T250 PolarHBondContact O-N 3.32Å; E246-T250 PolarHBondContact O-OG1 2.88Å; I247-T250 PolarHBondContact O-N 3.09Å; T250-L252 VanDerWaalsContact C-N 3.35Å; T250-L252 PolarHBondContact O-N 2.84Å; T250-F253 CarbonylContact O-C 3.6Å; T250-F253 PolarHBondContact O-N 3.2Å; T250-T254 WeakPolarHBondContact O-CB 3.44Å; T250-T254 PolarHBondContact O-N 3.38Å; T250-T254 PolarHBondContact O-OG1 2.71Å
251	F	95.9	Very high	94.3	Very high	9 Å²	9	61.7 Å²	61.7	4%	0.039	32%	0.315	C	S	.	.	H	α-helix	trans	-58.9	-45.2	176.1	178.7	-90.8	0	0	0	112.3	S87 N88 G91 A92 I247 G248 I249 F253 T254 F320 F324 V340	S87-F251 WeakPolarHBondContact OG-CZ 3.08Å; N88-F251 WeakPolarHBondContact O-CE2 3.43Å; N88-F251 WeakPolarHBondContact O-CZ 3.22Å; G91-F251 WeakPolarHBondContact CA-O 3.49Å; A92-F251 HydrophobicContact CB-CD1 4.44Å; A92-F251 HydrophobicContact CB-CE1 4Å; A92-F251 PolarHBondContact N-O 2.88Å; I247-F251 PolarHBondContact O-N 3.15Å; G248-F251 WeakPolarHBondContact O-CB 3.2Å; G248-F251 PolarHBondContact O-N 2.97Å; I249-F251 VanDerWaalsContact C-N 3.28Å; I249-F251 PolarHBondContact O-N 3.35Å; F251-F253 VanDerWaalsContact C-N 3.3Å; F251-F253 PolarHBondContact O-N 3.21Å; F251-T254 PolarHBondContact O-N 3.03Å; F251-F320 AromaticContact CD1-CD1 3.92Å; F251-F320 HydrophobicContact CD1-CD1 3.92Å; F251-F320 AromaticContact CD1-CE1 3.59Å; F251-F320 HydrophobicContact CD1-CE1 3.59Å; F251-F320 HydrophobicContact CE1-CD1 4.43Å; F251-F320 AromaticContact CE1-CE1 3.65Å; F251-F320 HydrophobicContact CE1-CE1 3.65Å; F251-F324 HydrophobicContact CB-CZ 4.17Å; F251-F324 HydrophobicContact CG-CZ 4.21Å; F251-V340 HydrophobicContact CD1-CG2 4.31Å; F251-V340 HydrophobicContact CD2-CG2 4.09Å; F251-V340 HydrophobicContact CE1-CG1 4.48Å; F251-V340 HydrophobicContact CE1-CG2 3.91Å; F251-V340 HydrophobicContact CE2-CG2 3.66Å; F251-V340 HydrophobicContact CG-CG2 4.4Å; F251-V340 HydrophobicContact CZ-CB 4.44Å; F251-V340 HydrophobicContact CZ-CG1 4.01Å; F251-V340 HydrophobicContact CZ-CG2 3.56Å
252	L	97.1	Very high	93.8	Very high	0 Å²	0	59.3 Å²	59.3	0%	0	30%	0.302	C	S	.	.	H	α-helix	trans	-60	-39.5	178.5	-73.7	178.8	0	0	0	112.7	L83 A92 L93 Y96 G248 I249 T250 I317 F320	L83-L252 HydrophobicContact CD2-CD2 3.39Å; L83-L252 HydrophobicContact CG-CD2 4.36Å; A92-L252 CarbonylContact C-O 3.56Å; A92-L252 HydrophobicContact CB-CD2 4.38Å; L93-L252 WeakPolarHBondContact CA-O 3.18Å; L93-L252 PolarHBondContact N-O 3.2Å; L93-L252 VanDerWaalsContact N-O 3.07Å; Y96-L252 HydrophobicContact CE2-CB 4.14Å; Y96-L252 HydrophobicContact CE2-CD2 4.37Å; G248-L252 WeakPolarHBondContact O-CG 3.5Å; G248-L252 PolarHBondContact O-N 3.39Å; I249-L252 WeakPolarHBondContact O-CB 3.41Å; I249-L252 PolarHBondContact O-N 2.8Å; I249-L252 VanDerWaalsContact O-N 3.12Å; T250-L252 VanDerWaalsContact C-N 3.35Å; T250-L252 PolarHBondContact O-N 2.84Å; L252-I317 HydrophobicContact CD1-CB 4.25Å; L252-I317 HydrophobicContact CD1-CG1 3.77Å; L252-F320 HydrophobicContact CD1-CB 3.81Å; L252-F320 HydrophobicContact CD1-CD2 4.42Å; L252-F320 HydrophobicContact CD1-CG 4.02Å; L252-F320 HydrophobicContact CD2-CB 4.4Å; L252-F320 HydrophobicContact CD2-CD1 3.68Å; L252-F320 HydrophobicContact CD2-CD2 3.86Å; L252-F320 HydrophobicContact CD2-CE1 3.79Å; L252-F320 HydrophobicContact CD2-CE2 3.93Å; L252-F320 HydrophobicContact CD2-CG 3.71Å; L252-F320 HydrophobicContact CD2-CZ 3.89Å; L252-F320 HydrophobicContact CG-CB 4.07Å; L252-F320 HydrophobicContact CG-CD1 3.91Å; L252-F320 HydrophobicContact CG-CD2 4.44Å; L252-F320 HydrophobicContact CG-CE1 4.47Å; L252-F320 HydrophobicContact CG-CG 3.89Å
253	F	97.3	Very high	93.3	Very high	98 Å²	98	58.5 Å²	58.5	43%	0.43	31%	0.307	S	S	.	.	T	Hydrogen-bonded Turn	trans	-99.3	14.5	-177.7	-68.2	-80	0	0	0	114.1	L93 I249 T250 F251 L313 I317	L93-F253 HydrophobicContact CD1-CD1 4.09Å; L93-F253 WeakPolarHBondContact CD2-O 3.16Å; I249-F253 HydrophobicContact CG2-CD2 3.89Å; I249-F253 HydrophobicContact CG2-CE2 4.19Å; I249-F253 WeakPolarHBondContact O-CD2 3.34Å; I249-F253 PolarHBondContact O-N 3.38Å; T250-F253 CarbonylContact O-C 3.6Å; T250-F253 PolarHBondContact O-N 3.2Å; F251-F253 VanDerWaalsContact C-N 3.3Å; F251-F253 PolarHBondContact O-N 3.21Å; F253-L313 HydrophobicContact CZ-CD1 4.4Å; F253-I317 HydrophobicContact CE2-CD1 4.17Å; F253-I317 HydrophobicContact CE2-CG1 4.43Å; F253-I317 HydrophobicContact CZ-CD1 4.28Å
254	T	96.4	Very high	92.8	Very high	47 Å²	47	56 Å²	56	29%	0.288	30%	0.299	S	S	.	.			trans	-94	125	171.3	-59.2	0	0	0	0	110.3	G90 G91 A92 L93 T250 F251	G90-T254 VanDerWaalsContact O-CB 3.28Å; G90-T254 WeakPolarHBondContact O-CB 3.23Å; G90-T254 WeakPolarHBondContact O-CG2 3.46Å; G91-T254 CarbonylContact C-O 3.43Å; G91-T254 WeakPolarHBondContact CA-O 3.31Å; A92-T254 PolarHBondContact N-O 3.42Å; L93-T254 WeakPolarHBondContact CB-O 3.33Å; L93-T254 PolarHBondContact N-O 3.13Å; L93-T254 VanDerWaalsContact N-O 3.15Å; T250-T254 WeakPolarHBondContact O-CB 3.44Å; T250-T254 PolarHBondContact O-N 3.38Å; T250-T254 PolarHBondContact O-OG1 2.71Å; F251-T254 PolarHBondContact O-N 3.03Å
255	P	92.8	Very high	92.5	Very high	47 Å²	47	52.5 Å²	52.5	31%	0.305	29%	0.286	S	S	.	.			trans	-75.1	141.7	178.9	29.3	-32.9	0	0	0	112.1	L93 W257	L93-P255 HydrophobicContact CB-CB 4.45Å; L93-P255 HydrophobicContact CD2-CB 4.18Å; L93-P255 HydrophobicContact CD2-CG 4.47Å; P255-W257 HydrophobicContact CB-CD2 4.11Å; P255-W257 HydrophobicContact CB-CG 4.46Å; P255-W257 HydrophobicContact CB-CZ2 3.76Å; P255-W257 HydrophobicContact CG-CZ2 4.2Å
256	S	89.9	Confident	92.1	Very high	14 Å²	14	56.4 Å²	56.4	10%	0.098	30%	0.301	C	S	.	.			trans	-118.8	80	167.8	-170.3	0	0	0	0	108.4	T94 S258 T259	T94-S256 PolarHBondContact OG1-N 2.9Å; T94-S256 PolarHBondContact OG1-O 3.36Å; S256-S258 PolarHBondContact O-N 2.83Å; S256-T259 PolarHBondContact O-N 3.5Å; S256-T259 PolarHBondContact O-OG1 3.21Å
257	W	91.2	Very high	91.6	Very high	159 Å²	159	53.5 Å²	53.5	60%	0.602	29%	0.288	S	S	*	.	G	3₁₀ helix	trans	-61.5	-26.4	-171.4	-62.5	114.8	0	0	0	114.1	I97 P255 T259 F260	I97-W257 HydrophobicContact CD1-CH2 3.93Å; I97-W257 HydrophobicContact CD1-CZ3 4.19Å; P255-W257 HydrophobicContact CB-CD2 4.11Å; P255-W257 HydrophobicContact CB-CG 4.46Å; P255-W257 HydrophobicContact CB-CZ2 3.76Å; P255-W257 HydrophobicContact CG-CZ2 4.2Å; W257-T259 PolarHBondContact O-N 2.75Å; W257-F260 VanDerWaalsContact O-CB 3.26Å; W257-F260 WeakPolarHBondContact O-CB 3.3Å; W257-F260 PolarHBondContact O-N 3.16Å
258	S	87.6	Confident	91.2	Very high	92 Å²	92	52.9 Å²	52.9	64%	0.643	29%	0.288	S	S	*	.	G	3₁₀ helix	trans	-60.8	-23.5	174.2	56.7	0	0	0	0	113.3	S256	S256-S258 PolarHBondContact O-N 2.83Å
259	T	87.7	Confident	91.1	Very high	15 Å²	15	52.9 Å²	52.9	9%	0.092	29%	0.288	C	S	.	.	G	3₁₀ helix	trans	-84.8	-15.8	176.7	64.1	0	0	0	0	113.2	N88 T94 S256 W257 T261 S262 L265	N88-T259 HydrophobicContact CB-CG2 4.3Å; N88-T259 WeakPolarHBondContact ND2-CG2 3.37Å; T94-T259 WeakPolarHBondContact CB-OG1 3.41Å; S256-T259 PolarHBondContact O-N 3.5Å; S256-T259 PolarHBondContact O-OG1 3.21Å; W257-T259 PolarHBondContact O-N 2.75Å; T259-T261 PolarHBondContact O-N 3.49Å; T259-S262 WeakPolarHBondContact O-CB 3.27Å; T259-S262 PolarHBondContact O-N 2.91Å; T259-L265 WeakPolarHBondContact O-CD2 3.49Å
260	F	89.3	Confident	90.7	Very high	70 Å²	70	50.7 Å²	50.7	31%	0.307	28%	0.278	S	S	.	.	T	Hydrogen-bonded Turn	trans	-63.3	-30.2	-175.8	-172.3	-93	0	0	0	112.4	T94 I97 I98 W257 S262 W266	T94-F260 HydrophobicContact CG2-CB 3.68Å; T94-F260 HydrophobicContact CG2-CD2 3.76Å; T94-F260 HydrophobicContact CG2-CG 4.23Å; I97-F260 HydrophobicContact CG2-CE2 4.41Å; I98-F260 HydrophobicContact CD1-CD2 4Å; I98-F260 HydrophobicContact CD1-CE2 4.33Å; I98-F260 HydrophobicContact CG1-CD2 4.04Å; I98-F260 HydrophobicContact CG1-CE2 3.9Å; W257-F260 VanDerWaalsContact O-CB 3.26Å; W257-F260 WeakPolarHBondContact O-CB 3.3Å; W257-F260 PolarHBondContact O-N 3.16Å; F260-S262 VanDerWaalsContact C-N 3.32Å; F260-W266 HydrophobicContact CE1-CZ2 4.05Å; F260-W266 HydrophobicContact CE2-CZ2 4.1Å; F260-W266 HydrophobicContact CZ-CH2 4.41Å; F260-W266 AromaticContact CZ-CZ2 3.69Å; F260-W266 HydrophobicContact CZ-CZ2 3.69Å; F260-W266 PolarHBondContact O-NE1 3.12Å
261	T	88.6	Confident	90.2	Very high	116 Å²	116	48.5 Å²	48.5	71%	0.712	27%	0.271	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85	-3.1	176.5	54.1	0	0	0	0	113.4	T259 P263	T259-T261 PolarHBondContact O-N 3.49Å; T261-P263 VanDerWaalsContact O-CD 3.3Å; T261-P263 WeakPolarHBondContact O-CD 3.48Å
262	S	88	Confident	90	Very high	40 Å²	40	48.1 Å²	48.1	28%	0.28	27%	0.269	S	S	.	.			trans	-75.6	117.8	-178.5	179.3	0	0	0	0	111.2	T259 F260 T264 L265 W266	T259-S262 WeakPolarHBondContact O-CB 3.27Å; T259-S262 PolarHBondContact O-N 2.91Å; F260-S262 VanDerWaalsContact C-N 3.32Å; S262-T264 VanDerWaalsContact C-N 3.26Å; S262-T264 PolarHBondContact O-N 3Å; S262-L265 WeakPolarHBondContact O-CB 3.43Å; S262-L265 PolarHBondContact O-N 3.33Å; S262-L265 VanDerWaalsContact O-N 3.13Å; S262-W266 PolarHBondContact O-N 2.86Å
263	P	85.1	Confident	89.8	Confident	61 Å²	61	48.1 Å²	48.1	40%	0.396	27%	0.269	S	S	.	.	H	α-helix	trans	-57.6	-39.2	176.4	-24.9	35.7	0	0	0	112.6	T261 L265 W266 I267 W498	T261-P263 VanDerWaalsContact O-CD 3.3Å; T261-P263 WeakPolarHBondContact O-CD 3.48Å; P263-L265 VanDerWaalsContact C-N 3.25Å; P263-L265 PolarHBondContact O-N 3.28Å; P263-W266 PolarHBondContact O-N 2.82Å; P263-W266 VanDerWaalsContact O-N 3.13Å; P263-I267 VanDerWaalsContact O-CG1 3.3Å; P263-I267 WeakPolarHBondContact O-CG1 3.43Å; P263-I267 PolarHBondContact O-N 3.19Å; P263-W498 HydrophobicContact CB-CH2 4.06Å; P263-W498 HydrophobicContact CB-CZ2 4.05Å; P263-W498 HydrophobicContact CB-CZ3 4.36Å; P263-W498 HydrophobicContact CG-CH2 4.15Å
264	T	84.9	Confident	89.5	Confident	63 Å²	63	44.3 Å²	44.3	39%	0.387	26%	0.256	S	S	.	.	H	α-helix	trans	-57.8	-38.3	178.4	-48.8	0	0	0	0	112	S262 I267 A268	S262-T264 VanDerWaalsContact C-N 3.26Å; S262-T264 PolarHBondContact O-N 3Å; T264-I267 PolarHBondContact O-N 3.41Å; T264-A268 WeakPolarHBondContact O-CB 3.29Å; T264-A268 PolarHBondContact O-N 3.14Å
265	L	90.2	Very high	89	Confident	6 Å²	6	43.9 Å²	43.9	3%	0.031	25%	0.25	C	S	.	.	H	α-helix	trans	-64.7	-43.9	177.8	-177.9	64.4	0	0	0	111.7	N86 T94 F95 I98 T259 S262 P263 A268 A269	N86-L265 HydrophobicContact CB-CD1 3.72Å; T94-L265 HydrophobicContact CG2-CD2 3.72Å; F95-L265 HydrophobicContact CB-CD1 4.06Å; F95-L265 HydrophobicContact CD2-CD1 3.65Å; F95-L265 HydrophobicContact CG-CD1 4.34Å; I98-L265 HydrophobicContact CD1-CD2 3.45Å; I98-L265 VanDerWaalsContact CD1-CD2 3.45Å; I98-L265 HydrophobicContact CD1-CG 3.76Å; T259-L265 WeakPolarHBondContact O-CD2 3.49Å; S262-L265 WeakPolarHBondContact O-CB 3.43Å; S262-L265 PolarHBondContact O-N 3.33Å; S262-L265 VanDerWaalsContact O-N 3.13Å; P263-L265 VanDerWaalsContact C-N 3.25Å; P263-L265 PolarHBondContact O-N 3.28Å; L265-A268 PolarHBondContact O-N 2.67Å; L265-A269 VanDerWaalsContact O-CB 3.29Å; L265-A269 WeakPolarHBondContact O-CB 3.08Å; L265-A269 PolarHBondContact O-N 2.86Å
266	W	90.3	Very high	88.8	Confident	83 Å²	83	41.7 Å²	41.7	31%	0.314	24%	0.236	S	C	.	.	H	α-helix	trans	-64.5	-40.9	178.3	-77.9	80.1	0	0	0	112.3	I98 L101 I102 F260 S262 P263 A269 A270	I98-W266 HydrophobicContact CD1-CD2 4.25Å; I98-W266 HydrophobicContact CD1-CG 4.29Å; I98-W266 HydrophobicContact CD1-CZ2 4.32Å; I98-W266 HydrophobicContact CG1-CD2 4.3Å; I98-W266 HydrophobicContact CG1-CH2 4.44Å; I98-W266 HydrophobicContact CG1-CZ2 3.97Å; I98-W266 HydrophobicContact CG2-CB 4.46Å; I98-W266 HydrophobicContact CG2-CD2 3.57Å; I98-W266 HydrophobicContact CG2-CE3 3.52Å; I98-W266 HydrophobicContact CG2-CG 4.01Å; I98-W266 HydrophobicContact CG2-CH2 4.39Å; I98-W266 HydrophobicContact CG2-CZ2 4.44Å; I98-W266 HydrophobicContact CG2-CZ3 3.95Å; L101-W266 HydrophobicContact CD1-CH2 4.31Å; I102-W266 HydrophobicContact CD1-CE3 4.23Å; I102-W266 HydrophobicContact CD1-CZ3 4.41Å; F260-W266 HydrophobicContact CE1-CZ2 4.05Å; F260-W266 HydrophobicContact CE2-CZ2 4.1Å; F260-W266 HydrophobicContact CZ-CH2 4.41Å; F260-W266 AromaticContact CZ-CZ2 3.69Å; F260-W266 HydrophobicContact CZ-CZ2 3.69Å; F260-W266 PolarHBondContact O-NE1 3.12Å; S262-W266 PolarHBondContact O-N 2.86Å; P263-W266 PolarHBondContact O-N 2.82Å; P263-W266 VanDerWaalsContact O-N 3.13Å; W266-A269 PolarHBondContact O-N 2.84Å; W266-A270 VanDerWaalsContact O-CB 3.24Å; W266-A270 WeakPolarHBondContact O-CB 3.46Å; W266-A270 PolarHBondContact O-N 3.44Å
267	I	84.8	Confident	89	Confident	38 Å²	38	41 Å²	41	20%	0.195	23%	0.231	C	C	.	.	H	α-helix	trans	-66.2	-46.7	178.1	-65.6	171.6	0	0	0	110.6	P263 T264 A269 A270 G271 L495 W498	P263-I267 VanDerWaalsContact O-CG1 3.3Å; P263-I267 WeakPolarHBondContact O-CG1 3.43Å; P263-I267 PolarHBondContact O-N 3.19Å; T264-I267 PolarHBondContact O-N 3.41Å; I267-A269 VanDerWaalsContact C-N 3.35Å; I267-A269 PolarHBondContact O-N 3.3Å; I267-A270 PolarHBondContact O-N 3.39Å; I267-G271 PolarHBondContact O-N 2.69Å; I267-L495 HydrophobicContact CB-CD2 4.04Å; I267-L495 HydrophobicContact CG1-CD2 3.57Å; I267-L495 HydrophobicContact CG2-CD2 4.13Å; I267-W498 HydrophobicContact CD1-CB 3.79Å; I267-W498 HydrophobicContact CD1-CD2 3.97Å; I267-W498 HydrophobicContact CD1-CG 3.28Å
268	A	88.8	Confident	89.1	Confident	24 Å²	24	33.9 Å²	33.9	20%	0.198	21%	0.206	C	C	.	.	H	α-helix	trans	-61.6	-44	177.9	0	0	0	0	0	111.6	N86 F95 T264 L265 A270 Q272	N86-A268 WeakPolarHBondContact ND2-CB 3.46Å; N86-A268 VanDerWaalsContact OD1-CB 3.29Å; N86-A268 WeakPolarHBondContact OD1-CB 3.38Å; F95-A268 HydrophobicContact CE2-CB 4.3Å; T264-A268 WeakPolarHBondContact O-CB 3.29Å; T264-A268 PolarHBondContact O-N 3.14Å; L265-A268 PolarHBondContact O-N 2.67Å; A268-A270 VanDerWaalsContact C-N 3.34Å; A268-Q272 WeakPolarHBondContact O-CB 3.5Å; A268-Q272 PolarHBondContact O-N 3.34Å
269	A	93.2	Very high	89.4	Confident	0 Å²	0	29.8 Å²	29.8	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-63.4	-40.1	175.5	0	0	0	0	0	111.9	F95 I98 W99 L265 W266 I267 N273	F95-A269 HydrophobicContact CD2-CB 4.32Å; F95-A269 HydrophobicContact CE2-CB 4Å; F95-A269 HydrophobicContact CZ-CB 4.26Å; I98-A269 HydrophobicContact CB-CB 4.19Å; I98-A269 HydrophobicContact CG2-CB 3.67Å; W99-A269 HydrophobicContact CB-CB 4.11Å; L265-A269 VanDerWaalsContact O-CB 3.29Å; L265-A269 WeakPolarHBondContact O-CB 3.08Å; L265-A269 PolarHBondContact O-N 2.86Å; W266-A269 PolarHBondContact O-N 2.84Å; I267-A269 VanDerWaalsContact C-N 3.35Å; I267-A269 PolarHBondContact O-N 3.3Å; A269-N273 WeakPolarHBondContact O-CB 3.37Å; A269-N273 PolarHBondContact O-N 3.4Å
270	A	89.9	Confident	89.7	Confident	3 Å²	3	29 Å²	29	3%	0.025	17%	0.172	C	C	.	.	H	α-helix	trans	-70.4	-47.3	180	0	0	0	0	0	113	I102 W266 I267 A268 Q272 N273 A274 L495	I102-A270 HydrophobicContact CD1-CB 4.04Å; I102-A270 HydrophobicContact CG1-CB 4.01Å; I102-A270 HydrophobicContact CG2-CB 4.07Å; W266-A270 VanDerWaalsContact O-CB 3.24Å; W266-A270 WeakPolarHBondContact O-CB 3.46Å; W266-A270 PolarHBondContact O-N 3.44Å; I267-A270 PolarHBondContact O-N 3.39Å; A268-A270 VanDerWaalsContact C-N 3.34Å; A270-Q272 VanDerWaalsContact C-N 3.3Å; A270-Q272 PolarHBondContact O-N 2.9Å; A270-N273 PolarHBondContact O-N 3.17Å; A270-A274 WeakPolarHBondContact O-CB 3.42Å; A270-A274 PolarHBondContact O-N 3.21Å; A270-L495 HydrophobicContact CB-CD1 3.89Å; A270-L495 HydrophobicContact CB-CD2 4.27Å
271	G	86	Confident	90	Very high	34 Å²	34	25.9 Å²	25.9	35%	0.351	16%	0.159	S	C	.	.	H	α-helix	trans	-59.9	-41.6	174.2	0	0	0	0	0	111.8	I267 F275	I267-G271 PolarHBondContact O-N 2.69Å; G271-F275 WeakPolarHBondContact O-CB 3.49Å; G271-F275 PolarHBondContact O-N 3.4Å; G271-F275 VanDerWaalsContact O-N 3.08Å
272	Q	90.6	Very high	90.4	Very high	1 Å²	1	20.4 Å²	20.4	1%	0.005	13%	0.125	C	C	.	.	H	α-helix	trans	-66.3	-43.3	176.1	-173	63.8	42.3	0	0	112.1	F79 V82 F95 A268 A270 F275 D276	F79-Q272 HydrophobicContact CD2-CG 3.59Å; F79-Q272 HydrophobicContact CE2-CG 4.16Å; V82-Q272 HydrophobicContact CG1-CB 4.17Å; V82-Q272 HydrophobicContact CG1-CG 4.19Å; F95-Q272 HydrophobicContact CZ-CB 4.17Å; F95-Q272 HydrophobicContact CZ-CG 4.31Å; A268-Q272 WeakPolarHBondContact O-CB 3.5Å; A268-Q272 PolarHBondContact O-N 3.34Å; A270-Q272 VanDerWaalsContact C-N 3.3Å; A270-Q272 PolarHBondContact O-N 2.9Å; Q272-F275 PolarHBondContact O-N 3.45Å; Q272-D276 VanDerWaalsContact NE2-CG 3.3Å; Q272-D276 PolarHBondContact NE2-OD1 2.78Å; Q272-D276 PolarHBondContact NE2-OD2 2.88Å; Q272-D276 VanDerWaalsContact O-CB 3.3Å; Q272-D276 WeakPolarHBondContact O-CB 3.45Å; Q272-D276 PolarHBondContact O-N 2.98Å
273	N	94.3	Very high	90.8	Very high	0 Å²	0	18.5 Å²	18.5	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-67.4	-40.6	-179.9	-171.1	-101.3	0	0	0	112.7	W99 I102 L103 S107 A269 A270 F275 D276 T277 N309	W99-N273 VanDerWaalsContact CD1-CB 3.49Å; W99-N273 HydrophobicContact CG-CB 4.42Å; W99-N273 PolarHBondContact NE1-ND2 2.97Å; I102-N273 HydrophobicContact CB-CB 4.25Å; I102-N273 HydrophobicContact CG2-CB 3.97Å; L103-N273 VanDerWaalsContact CA-OD1 3.27Å; L103-N273 WeakPolarHBondContact CA-OD1 3.44Å; L103-N273 PolarHBondContact N-OD1 2.93Å; S107-N273 VanDerWaalsContact CB-OD1 3.28Å; S107-N273 WeakPolarHBondContact CB-OD1 2.78Å; S107-N273 PolarHBondContact OG-OD1 3.3Å; A269-N273 WeakPolarHBondContact O-CB 3.37Å; A269-N273 PolarHBondContact O-N 3.4Å; A270-N273 PolarHBondContact O-N 3.17Å; N273-F275 VanDerWaalsContact C-N 3.35Å; N273-D276 PolarHBondContact O-N 2.63Å; N273-T277 WeakPolarHBondContact O-CB 3.35Å; N273-T277 WeakPolarHBondContact O-CG2 3.4Å; N273-T277 PolarHBondContact O-N 3.5Å; N273-T277 PolarHBondContact O-OG1 3.41Å; N273-N309 PolarHBondContact ND2-ND2 3.43Å; N273-N309 VanDerWaalsContact ND2-ND2 3.19Å
274	A	90	Very high	91.5	Very high	18 Å²	18	15.7 Å²	15.7	15%	0.149	9%	0.093	C	C	.	.	H	α-helix	trans	-62.7	-43.4	175.9	0	0	0	0	0	111.2	A270 S278 S279	A270-A274 WeakPolarHBondContact O-CB 3.42Å; A270-A274 PolarHBondContact O-N 3.21Å; A274-S278 PolarHBondContact O-N 3.15Å; A274-S278 VanDerWaalsContact O-N 3.14Å; A274-S279 PolarHBondContact O-N 3.06Å; A274-S279 VanDerWaalsContact O-N 3.16Å
275	F	85.9	Confident	92.1	Very high	38 Å²	38	12.7 Å²	12.7	17%	0.167	8%	0.075	C	C	.	.	H	α-helix	trans	-64.2	-49.3	175.8	-169.7	-94.4	0	0	0	111.9	G271 Q272 N273 T277 S278 M281	G271-F275 WeakPolarHBondContact O-CB 3.49Å; G271-F275 PolarHBondContact O-N 3.4Å; G271-F275 VanDerWaalsContact O-N 3.08Å; Q272-F275 PolarHBondContact O-N 3.45Å; N273-F275 VanDerWaalsContact C-N 3.35Å; F275-T277 VanDerWaalsContact C-N 3.32Å; F275-T277 PolarHBondContact O-N 2.82Å; F275-S278 PolarHBondContact O-N 2.98Å; F275-M281 HydrophobicContact CD2-CE 4.29Å
276	D	88.4	Confident	92.4	Very high	0 Å²	0	12.4 Å²	12.4	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-60.4	-40.9	-179.2	-74.8	-16.3	0	0	0	111.8	F79 W99 Q272 N273 S278 N308	F79-D276 VanDerWaalsContact CD2-OD2 3.24Å; F79-D276 WeakPolarHBondContact CD2-OD2 3.43Å; W99-D276 PolarHBondContact NE1-OD2 3.47Å; Q272-D276 VanDerWaalsContact NE2-CG 3.3Å; Q272-D276 PolarHBondContact NE2-OD1 2.78Å; Q272-D276 PolarHBondContact NE2-OD2 2.88Å; Q272-D276 VanDerWaalsContact O-CB 3.3Å; Q272-D276 WeakPolarHBondContact O-CB 3.45Å; Q272-D276 PolarHBondContact O-N 2.98Å; N273-D276 PolarHBondContact O-N 2.63Å; D276-S278 VanDerWaalsContact C-N 3.33Å; D276-N308 PolarHBondContact O-ND2 3.09Å; D276-N308 PolarHBondContact O-OD1 2.84Å
277	T	94.3	Very high	92.7	Very high	1 Å²	1	8.4 Å²	8.4	1%	0.006	6%	0.058	C	C	.	.	H	α-helix	trans	-87.5	-5.3	-176.1	58.8	0	0	0	0	113.4	L103 S107 N273 F275 S279 P305	L103-T277 HydrophobicContact CD1-CG2 3.91Å; S107-T277 WeakPolarHBondContact CB-OG1 3.42Å; S107-T277 PolarHBondContact OG-OG1 3.33Å; N273-T277 WeakPolarHBondContact O-CB 3.35Å; N273-T277 WeakPolarHBondContact O-CG2 3.4Å; N273-T277 PolarHBondContact O-N 3.5Å; N273-T277 PolarHBondContact O-OG1 3.41Å; F275-T277 VanDerWaalsContact C-N 3.32Å; F275-T277 PolarHBondContact O-N 2.82Å; T277-S279 PolarHBondContact O-N 3.01Å; T277-S279 WeakPolarHBondContact OG1-CB 3.25Å; T277-P305 HydrophobicContact CG2-CB 3.68Å
278	S	93.4	Very high	93.3	Very high	9 Å²	9	6.6 Å²	6.6	6%	0.063	5%	0.049	C	C	.	.	T	Hydrogen-bonded Turn	trans	56.2	26	-170.2	-60	0	0	0	0	114.3	G69 A274 F275 D276 G280 M281	G69-S278 PolarHBondContact O-OG 3.42Å; A274-S278 PolarHBondContact O-N 3.15Å; A274-S278 VanDerWaalsContact O-N 3.14Å; F275-S278 PolarHBondContact O-N 2.98Å; D276-S278 VanDerWaalsContact C-N 3.33Å; S278-G280 PolarHBondContact O-N 3.36Å; S278-M281 VanDerWaalsContact CB-SD 3.59Å; S278-M281 WeakPolarHBondContact O-CB 3.45Å; S278-M281 PolarHBondContact O-N 3.27Å
279	S	94.8	Very high	93.6	Very high	5 Å²	5	5.5 Å²	5.5	4%	0.035	4%	0.039	C	C	.	.	T	Hydrogen-bonded Turn	trans	-68.4	127.4	-179.6	171.8	0	0	0	0	110.9	I110 A274 T277 M281	I110-S279 WeakPolarHBondContact CB-OG 3.24Å; I110-S279 WeakPolarHBondContact CG2-OG 3.33Å; A274-S279 PolarHBondContact O-N 3.06Å; A274-S279 VanDerWaalsContact O-N 3.16Å; T277-S279 PolarHBondContact O-N 3.01Å; T277-S279 WeakPolarHBondContact OG1-CB 3.25Å; S279-M281 VanDerWaalsContact C-N 3.35Å
280	G	94.3	Very high	93.6	Very high	0 Å²	0	5.8 Å²	5.8	0%	0	4%	0.041	C	C	.	.	T	Hydrogen-bonded Turn	trans	86.9	0.6	-178.7	0	0	0	0	0	114.1	E114 S278 S445	E114-G280 WeakPolarHBondContact OE1-CA 3.46Å; E114-G280 PolarHBondContact OE1-N 3.24Å; S278-G280 PolarHBondContact O-N 3.36Å; G280-S445 WeakPolarHBondContact O-CB 3.18Å
281	M	95	Very high	93.7	Very high	4 Å²	4	6 Å²	6	2%	0.02	4%	0.041	C	C	.	.	S	Bend	trans	-80.5	-22.5	176.9	-64.2	-174.8	-174.7	0	0	112.8	V148 L151 F275 S278 S279 I283 I394 L442	V148-M281 HydrophobicContact CG2-CB 3.96Å; V148-M281 HydrophobicContact CG2-CG 4.4Å; V148-M281 WeakPolarHBondContact CG2-O 3.45Å; L151-M281 HydrophobicContact CD2-CE 4.21Å; L151-M281 HydrophobicContact CD2-SD 4.27Å; F275-M281 HydrophobicContact CD2-CE 4.29Å; S278-M281 VanDerWaalsContact CB-SD 3.59Å; S278-M281 WeakPolarHBondContact O-CB 3.45Å; S278-M281 PolarHBondContact O-N 3.27Å; S279-M281 VanDerWaalsContact C-N 3.35Å; M281-I283 HydrophobicContact CB-CD1 4.41Å; M281-I283 HydrophobicContact CB-CG1 4.1Å; M281-I283 HydrophobicContact SD-CD1 4.13Å; M281-I394 WeakPolarHBondContact O-CD1 3.41Å; M281-L442 HydrophobicContact CB-CD2 4.4Å; M281-L442 HydrophobicContact CE-CD1 3.58Å; M281-L442 HydrophobicContact CG-CD1 4.17Å; M281-L442 HydrophobicContact CG-CD2 3.66Å
282	G	96.7	Very high	93.9	Very high	0 Å²	0	6 Å²	6	0%	0	4%	0.036	C	C	.	.	S	Bend	trans	85.8	7.2	-173.9	0	0	0	0	0	114	E114 T285 T286	E114-G282 WeakPolarHBondContact OE2-CA 3.4Å; E114-G282 PolarHBondContact OE2-N 2.87Å; G282-T285 PolarHBondContact O-N 3Å; G282-T286 WeakPolarHBondContact O-CB 3.2Å; G282-T286 PolarHBondContact O-N 3.19Å; G282-T286 PolarHBondContact O-OG1 3.46Å
283	I	97.2	Very high	93.9	Very high	0 Å²	0	8.9 Å²	8.9	0%	0	5%	0.047	C	C	.	.	H	α-helix	trans	-62.2	-50	176.1	-66.9	180	0	0	0	109.1	E114 M281 T285 T286 Y287 I391 I394	E114-I283 PolarHBondContact OE2-N 3.45Å; M281-I283 HydrophobicContact CB-CD1 4.41Å; M281-I283 HydrophobicContact CB-CG1 4.1Å; M281-I283 HydrophobicContact SD-CD1 4.13Å; I283-T285 VanDerWaalsContact C-N 3.31Å; I283-T285 PolarHBondContact O-N 2.91Å; I283-T286 WeakPolarHBondContact O-CB 3.35Å; I283-T286 PolarHBondContact O-N 3.36Å; I283-T286 VanDerWaalsContact O-N 3.1Å; I283-Y287 HydrophobicContact CG2-CD2 4.11Å; I283-Y287 HydrophobicContact CG2-CE2 4.19Å; I283-Y287 PolarHBondContact O-N 2.8Å; I283-I391 HydrophobicContact CD1-CG1 4.04Å; I283-I394 HydrophobicContact CB-CD1 4.34Å; I283-I394 HydrophobicContact CG1-CD1 3.55Å; I283-I394 HydrophobicContact CG1-CG1 4.49Å
284	M	97.9	Very high	93.7	Very high	2 Å²	2	12.7 Å²	12.7	1%	0.01	7%	0.067	C	C	.	.	H	α-helix	trans	-72.5	-29.9	-177.4	-57.9	-46.9	158.8	0	0	111.5	C66 A70 L111 E114 Y115 T286 S288	C66-M284 HydrophobicContact CB-CE 4.43Å; C66-M284 HydrophobicContact CB-SD 3.94Å; C66-M284 WeakPolarHBondContact O-CE 3.44Å; A70-M284 HydrophobicContact CB-CE 4.13Å; L111-M284 HydrophobicContact CD2-CB 4.41Å; L111-M284 HydrophobicContact CD2-CG 3.75Å; E114-M284 HydrophobicContact CB-CB 3.87Å; E114-M284 PolarHBondContact OE2-N 3.38Å; Y115-M284 HydrophobicContact CD1-CB 4.27Å; Y115-M284 HydrophobicContact CD2-CB 3.93Å; Y115-M284 HydrophobicContact CD2-CG 4.32Å; Y115-M284 HydrophobicContact CE1-CB 4.11Å; Y115-M284 HydrophobicContact CE1-CG 4.37Å; Y115-M284 HydrophobicContact CE1-SD 4.17Å; Y115-M284 HydrophobicContact CE2-CB 3.76Å; Y115-M284 HydrophobicContact CE2-CG 3.67Å; Y115-M284 HydrophobicContact CE2-SD 4.22Å; Y115-M284 HydrophobicContact CG-CB 4.16Å; Y115-M284 PolarHBondContact OH-SD 3.45Å; M284-T286 VanDerWaalsContact C-N 3.34Å; M284-S288 WeakPolarHBondContact O-CB 3.45Å; M284-S288 PolarHBondContact O-N 3.34Å; M284-S288 PolarHBondContact O-OG 3.26Å
285	T	98.3	Very high	93.8	Very high	0 Å²	0	12.7 Å²	12.7	0%	0	7%	0.066	C	C	.	.	H	α-helix	trans	-59.1	-49.1	167.6	-53	0	0	0	0	110.1	E114 L117 G118 V125 G282 I283 S288 T289	E114-T285 VanDerWaalsContact CA-OG1 3.29Å; E114-T285 WeakPolarHBondContact CA-OG1 3.3Å; E114-T285 WeakPolarHBondContact CB-OG1 3.29Å; E114-T285 WeakPolarHBondContact CG-OG1 3.36Å; E114-T285 VanDerWaalsContact O-CA 3.27Å; E114-T285 WeakPolarHBondContact O-CA 3.43Å; E114-T285 PolarHBondContact OE2-N 3Å; E114-T285 PolarHBondContact OE2-OG1 3.14Å; L117-T285 HydrophobicContact CB-CG2 4.42Å; L117-T285 HydrophobicContact CD2-CG2 4.02Å; L117-T285 HydrophobicContact CG-CG2 4.24Å; G118-T285 VanDerWaalsContact CA-O 3.28Å; G118-T285 WeakPolarHBondContact CA-O 3.31Å; V125-T285 HydrophobicContact CG2-CG2 3.88Å; G282-T285 PolarHBondContact O-N 3Å; I283-T285 VanDerWaalsContact C-N 3.31Å; I283-T285 PolarHBondContact O-N 2.91Å; T285-S288 PolarHBondContact O-OG 2.62Å; T285-S288 VanDerWaalsContact O-OG 3.06Å; T285-T289 WeakPolarHBondContact O-CG2 3.18Å; T285-T289 PolarHBondContact O-N 3.04Å
286	T	97.5	Very high	94.2	Very high	0 Å²	0	16.5 Å²	16.5	0%	0	8%	0.08	C	C	.	.	H	α-helix	trans	-64.7	-47.6	-177.9	-64	0	0	0	0	112.5	G282 I283 M284 T289 F290 Q393 I394 L397	G282-T286 WeakPolarHBondContact O-CB 3.2Å; G282-T286 PolarHBondContact O-N 3.19Å; G282-T286 PolarHBondContact O-OG1 3.46Å; I283-T286 WeakPolarHBondContact O-CB 3.35Å; I283-T286 PolarHBondContact O-N 3.36Å; I283-T286 VanDerWaalsContact O-N 3.1Å; M284-T286 VanDerWaalsContact C-N 3.34Å; T286-T289 WeakPolarHBondContact O-CB 3.36Å; T286-T289 WeakPolarHBondContact O-CG2 3.43Å; T286-T289 PolarHBondContact O-N 3.11Å; T286-T289 PolarHBondContact O-OG1 3.46Å; T286-F290 WeakPolarHBondContact O-CD2 3.31Å; T286-F290 WeakPolarHBondContact O-CE2 3.16Å; T286-Q393 HydrophobicContact CG2-CG 3.93Å; T286-I394 HydrophobicContact CG2-CG1 4.44Å; T286-I394 WeakPolarHBondContact OG1-CG1 3.36Å; T286-L397 HydrophobicContact CG2-CB 4.29Å; T286-L397 HydrophobicContact CG2-CD2 3.87Å
287	Y	96.7	Very high	94.6	Very high	0 Å²	0	16.5 Å²	16.5	0%	0	8%	0.08	C	C	.	.	H	α-helix	trans	-69.1	-39	-179.1	-76.6	-7.8	0	0	0	113.1	F56 S65 I217 I283 T289 F290 S390 Q393	F56-Y287 WeakPolarHBondContact CE2-O 3.39Å; F56-Y287 HydrophobicContact CZ-CD1 4.34Å; F56-Y287 HydrophobicContact CZ-CG 4.17Å; S65-Y287 WeakPolarHBondContact O-CE2 3.46Å; I217-Y287 VanDerWaalsContact CG2-OH 3.31Å; I217-Y287 WeakPolarHBondContact CG2-OH 3.43Å; I283-Y287 HydrophobicContact CG2-CD2 4.11Å; I283-Y287 HydrophobicContact CG2-CE2 4.19Å; I283-Y287 PolarHBondContact O-N 2.8Å; Y287-T289 PolarHBondContact O-N 2.79Å; Y287-T289 VanDerWaalsContact O-N 3.14Å; Y287-F290 PolarHBondContact O-N 3.32Å; Y287-S390 WeakPolarHBondContact CE2-OG 3.41Å; Y287-S390 VanDerWaalsContact OH-CA 3.29Å; Y287-S390 WeakPolarHBondContact OH-CA 3.34Å; Y287-S390 WeakPolarHBondContact OH-CB 3.44Å; Y287-S390 PolarHBondContact OH-OG 2.87Å; Y287-Q393 HydrophobicContact CE1-CB 4.45Å; Y287-Q393 HydrophobicContact CE1-CG 4.22Å
288	S	96	Very high	94.7	Very high	0 Å²	0	16.7 Å²	16.7	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-65.7	-16.8	176.8	62.3	0	0	0	0	113.5	E114 Y115 G118 R119 M284 T285 F290 M291	E114-S288 PolarHBondContact O-OG 2.82Å; Y115-S288 VanDerWaalsContact O-CB 3.26Å; Y115-S288 WeakPolarHBondContact O-CB 3.38Å; Y115-S288 PolarHBondContact O-OG 3.42Å; Y115-S288 VanDerWaalsContact O-OG 3.1Å; G118-S288 WeakPolarHBondContact CA-OG 3.47Å; R119-S288 VanDerWaalsContact CA-O 3.28Å; R119-S288 WeakPolarHBondContact CA-O 3.29Å; R119-S288 PolarHBondContact N-O 2.78Å; R119-S288 PolarHBondContact N-OG 2.94Å; M284-S288 WeakPolarHBondContact O-CB 3.45Å; M284-S288 PolarHBondContact O-N 3.34Å; M284-S288 PolarHBondContact O-OG 3.26Å; T285-S288 PolarHBondContact O-OG 2.62Å; T285-S288 VanDerWaalsContact O-OG 3.06Å; S288-F290 PolarHBondContact O-N 3.23Å; S288-F290 VanDerWaalsContact O-N 3.13Å; S288-M291 WeakPolarHBondContact O-CB 3.39Å; S288-M291 PolarHBondContact O-N 2.94Å
289	T	95.2	Very high	94.9	Very high	0 Å²	0	17.3 Å²	17.3	0%	0	9%	0.085	C	C	.	.	T	Hydrogen-bonded Turn	trans	-64.6	-13.3	170.6	79.3	0	0	0	0	114.8	K53 G118 N123 T285 T286 Y287 L397	K53-T289 PolarHBondContact NZ-OG1 3.36Å; G118-T289 WeakPolarHBondContact O-CA 3.5Å; N123-T289 WeakPolarHBondContact O-CG2 3.47Å; T285-T289 WeakPolarHBondContact O-CG2 3.18Å; T285-T289 PolarHBondContact O-N 3.04Å; T286-T289 WeakPolarHBondContact O-CB 3.36Å; T286-T289 WeakPolarHBondContact O-CG2 3.43Å; T286-T289 PolarHBondContact O-N 3.11Å; T286-T289 PolarHBondContact O-OG1 3.46Å; Y287-T289 PolarHBondContact O-N 2.79Å; Y287-T289 VanDerWaalsContact O-N 3.14Å; T289-L397 HydrophobicContact CG2-CD2 4.03Å
290	F	93.3	Very high	94.9	Very high	7 Å²	7	18.3 Å²	18.3	3%	0.031	9%	0.088	C	C	.	.	T	Hydrogen-bonded Turn	trans	-107	13.1	176.5	-49.9	-70.7	0	0	0	112.2	K53 S54 M55 F56 V214 T286 Y287 S288 L397	K53-F290 HydrophobicContact CD-CD1 4.34Å; K53-F290 HydrophobicContact CD-CE1 4.29Å; K53-F290 VanDerWaalsContact CE-CE1 3.47Å; K53-F290 HydrophobicContact CG-CD1 4.23Å; K53-F290 HydrophobicContact CG-CE1 4.15Å; S54-F290 WeakPolarHBondContact O-CD1 3.37Å; M55-F290 VanDerWaalsContact CE-O 3.22Å; M55-F290 WeakPolarHBondContact CE-O 3.44Å; M55-F290 VanDerWaalsContact SD-O 3.37Å; F56-F290 HydrophobicContact CD2-CB 3.79Å; F56-F290 HydrophobicContact CE2-CB 3.85Å; F56-F290 HydrophobicContact CE2-CD2 4.45Å; F56-F290 PolarHBondContact N-O 3.21Å; V214-F290 HydrophobicContact CB-CD1 4.48Å; V214-F290 HydrophobicContact CB-CD2 4.35Å; V214-F290 HydrophobicContact CB-CE1 4.46Å; V214-F290 HydrophobicContact CB-CE2 4.38Å; V214-F290 HydrophobicContact CB-CG 4.4Å; V214-F290 HydrophobicContact CB-CZ 4.42Å; V214-F290 HydrophobicContact CG1-CD1 4.28Å; V214-F290 HydrophobicContact CG1-CG 4.43Å; V214-F290 HydrophobicContact CG2-CB 4.4Å; V214-F290 HydrophobicContact CG2-CD2 3.8Å; V214-F290 HydrophobicContact CG2-CE2 4.17Å; V214-F290 HydrophobicContact CG2-CG 4.03Å; T286-F290 WeakPolarHBondContact O-CD2 3.31Å; T286-F290 WeakPolarHBondContact O-CE2 3.16Å; Y287-F290 PolarHBondContact O-N 3.32Å; S288-F290 PolarHBondContact O-N 3.23Å; S288-F290 VanDerWaalsContact O-N 3.13Å; F290-L397 HydrophobicContact CZ-CD1 4.45Å
291	M	92	Very high	95.1	Very high	7 Å²	7	18.3 Å²	18.3	3%	0.034	9%	0.088	C	C	.	.			trans	-104.5	151.1	178.1	-69	-179.4	175.4	0	0	111.2	M55 F56 Y115 R122 S288 S295	M55-M291 VanDerWaalsContact CE-C 3.47Å; F56-M291 HydrophobicContact CD2-CG 4.36Å; F56-M291 HydrophobicContact CE2-CE 4.4Å; F56-M291 HydrophobicContact CE2-CG 4.47Å; Y115-M291 HydrophobicContact CD1-SD 4.4Å; Y115-M291 HydrophobicContact CE1-CE 4.28Å; R122-M291 PolarHBondContact NH1-O 3.46Å; S288-M291 WeakPolarHBondContact O-CB 3.39Å; S288-M291 PolarHBondContact O-N 2.94Å; M291-S295 WeakPolarHBondContact CB-OG 3.34Å
292	S	90.7	Very high	95.2	Very high	35 Å²	35	21.8 Å²	21.8	25%	0.245	10%	0.103	C	C	.	.			trans	-89.3	174.3	175.6	68.7	0	0	0	0	111.1	R119 D294 S295	R119-S292 VanDerWaalsContact CD-O 3.25Å; R119-S292 WeakPolarHBondContact CD-O 3.4Å; S292-D294 PolarHBondContact O-N 3.37Å; S292-D294 PolarHBondContact OG-N 3.19Å; S292-S295 WeakPolarHBondContact O-CB 3.48Å; S292-S295 PolarHBondContact O-N 3.35Å; S292-S295 VanDerWaalsContact O-N 3.12Å; S292-S295 PolarHBondContact O-OG 3.46Å
293	R	90.1	Very high	95.2	Very high	61 Å²	61	25.9 Å²	25.9	23%	0.23	13%	0.125	C	C	.	.	T	Hydrogen-bonded Turn	trans	-64	-20.1	175.1	-64.1	-179.7	62.9	-165.7	-2	113.8	R119 S295 F469 I471	R119-R293 PolarHBondContact NH1-O 3.19Å; R293-S295 VanDerWaalsContact C-N 3.33Å; R293-F469 HydrophobicContact CG-CD1 4.35Å; R293-F469 HydrophobicContact CG-CE1 3.73Å; R293-F469 HydrophobicContact CG-CE2 4.06Å; R293-F469 HydrophobicContact CG-CZ 3.57Å; R293-F469 PolarHBondContact NE-O 2.93Å; R293-F469 PolarHBondContact NH2-O 3.37Å; R293-I471 HydrophobicContact CB-CD1 3.8Å; R293-I471 HydrophobicContact CB-CG1 4Å; R293-I471 PolarHBondContact O-N 3.43Å
294	D	89.7	Confident	95.3	Very high	80 Å²	80	26 Å²	26	43%	0.428	13%	0.125	S	C	.	.	T	Hydrogen-bonded Turn	trans	-76.1	-22.4	176	-169.8	51.9	0	0	0	112.7	S292 R296 N472	S292-D294 PolarHBondContact O-N 3.37Å; S292-D294 PolarHBondContact OG-N 3.19Å; D294-R296 PolarHBondContact O-N 2.87Å; D294-N472 WeakPolarHBondContact OD1-CB 3.3Å; D294-N472 PolarHBondContact OD1-ND2 3.42Å
295	S	92.3	Very high	95.3	Very high	18 Å²	18	25.9 Å²	25.9	13%	0.126	13%	0.125	C	C	.	.	S	Bend	trans	-62.9	125.8	178	-62	0	0	0	0	111.7	R119 M291 S292 R293 I297	R119-S295 PolarHBondContact NH1-O 3.01Å; R119-S295 VanDerWaalsContact NH1-O 3.15Å; M291-S295 WeakPolarHBondContact CB-OG 3.34Å; S292-S295 WeakPolarHBondContact O-CB 3.48Å; S292-S295 PolarHBondContact O-N 3.35Å; S292-S295 VanDerWaalsContact O-N 3.12Å; S292-S295 PolarHBondContact O-OG 3.46Å; R293-S295 VanDerWaalsContact C-N 3.33Å; S295-I297 VanDerWaalsContact C-N 3.28Å; S295-I297 PolarHBondContact O-N 3.4Å
296	R	94.8	Very high	95.2	Very high	118 Å²	118	28.8 Å²	28.8	45%	0.445	14%	0.14	S	C	.	.			trans	-80.3	63.4	-171.5	-65	-176.9	54.6	-169.7	-3.1	113.2	D294 V298 S299 Y300 N472 D473	D294-R296 PolarHBondContact O-N 2.87Å; R296-V298 VanDerWaalsContact C-N 3.33Å; R296-V298 PolarHBondContact O-N 3Å; R296-S299 PolarHBondContact NE-OG 3.04Å; R296-S299 PolarHBondContact NH2-OG 3.12Å; R296-S299 WeakPolarHBondContact O-CB 3.45Å; R296-S299 PolarHBondContact O-N 3.12Å; R296-S299 VanDerWaalsContact O-N 3.11Å; R296-Y300 HydrophobicContact CB-CD1 4.37Å; R296-Y300 HydrophobicContact CB-CE1 3.97Å; R296-Y300 HydrophobicContact CB-CE2 4.45Å; R296-Y300 WeakPolarHBondContact O-CB 3.46Å; R296-Y300 WeakPolarHBondContact O-CD1 3.18Å; R296-Y300 WeakPolarHBondContact O-CD2 3.24Å; R296-Y300 PolarHBondContact O-N 3.32Å; R296-N472 VanDerWaalsContact CD-O 3.3Å; R296-N472 WeakPolarHBondContact CD-O 3.39Å; R296-N472 WeakPolarHBondContact CG-O 3.46Å; R296-D473 VanDerWaalsContact CA-CG 3.42Å; R296-D473 VanDerWaalsContact CA-OD2 3.28Å; R296-D473 WeakPolarHBondContact CA-OD2 3.42Å; R296-D473 HydrophobicContact CB-CB 4.3Å; R296-D473 WeakPolarHBondContact CB-OD1 3.44Å; R296-D473 HydrophobicContact CG-CB 4.27Å; R296-D473 IonicContact NE-OD1 3.77Å
297	I	95.7	Very high	95.2	Very high	0 Å²	0	31 Å²	31	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-55.9	-37.2	-172.6	56.5	128	0	0	0	115.3	Y115 R119 S295 S301 I466 D473	Y115-I297 HydrophobicContact CD1-CG2 4.37Å; Y115-I297 HydrophobicContact CG-CB 4.47Å; R119-I297 HydrophobicContact CB-CG2 4.34Å; S295-I297 VanDerWaalsContact C-N 3.28Å; S295-I297 PolarHBondContact O-N 3.4Å; I297-S301 VanDerWaalsContact O-CB 3.3Å; I297-S301 WeakPolarHBondContact O-CB 3.32Å; I297-S301 PolarHBondContact O-N 3.31Å; I297-S301 PolarHBondContact O-OG 2.96Å; I297-I466 HydrophobicContact CD1-CG2 4.04Å; I297-D473 PolarHBondContact N-OD2 3.25Å
298	V	97.6	Very high	95.3	Very high	4 Å²	4	31 Å²	31	2%	0.024	15%	0.151	C	C	.	.	H	α-helix	trans	-66.4	-51.3	176.3	-177.1	0	0	0	0	108.1	R296 Y300 S301 F302 I466 D473 C474 L476	R296-V298 VanDerWaalsContact C-N 3.33Å; R296-V298 PolarHBondContact O-N 3Å; V298-Y300 VanDerWaalsContact C-N 3.32Å; V298-Y300 PolarHBondContact O-N 2.92Å; V298-S301 WeakPolarHBondContact O-CB 3.49Å; V298-S301 PolarHBondContact O-N 3.02Å; V298-S301 VanDerWaalsContact O-N 3.17Å; V298-F302 HydrophobicContact CG1-CE2 4.34Å; V298-F302 WeakPolarHBondContact O-CD2 3.47Å; V298-F302 PolarHBondContact O-N 3.3Å; V298-I466 HydrophobicContact CG2-CG2 3.39Å; V298-D473 WeakPolarHBondContact CA-OD2 3.3Å; V298-D473 WeakPolarHBondContact CB-OD2 3.2Å; V298-D473 PolarHBondContact N-OD2 3.35Å; V298-C474 WeakPolarHBondContact CG1-SG 3.5Å; V298-L476 HydrophobicContact CG1-CB 4.46Å; V298-L476 HydrophobicContact CG1-CD1 4.16Å; V298-L476 HydrophobicContact CG2-CB 4.26Å
299	S	97	Very high	95.3	Very high	22 Å²	22	31.5 Å²	31.5	15%	0.154	15%	0.154	C	C	.	.	H	α-helix	trans	-56.9	-44.5	176.8	-57.1	0	0	0	0	112.1	R296 S301 F302 L303 D473	R296-S299 PolarHBondContact NE-OG 3.04Å; R296-S299 PolarHBondContact NH2-OG 3.12Å; R296-S299 WeakPolarHBondContact O-CB 3.45Å; R296-S299 PolarHBondContact O-N 3.12Å; R296-S299 VanDerWaalsContact O-N 3.11Å; S299-S301 PolarHBondContact O-N 3.49Å; S299-F302 PolarHBondContact O-N 2.87Å; S299-L303 WeakPolarHBondContact O-CB 3.35Å; S299-L303 PolarHBondContact O-N 2.95Å; S299-D473 PolarHBondContact N-OD1 2.87Å; S299-D473 PolarHBondContact OG-OD1 3.5Å
300	Y	96.2	Very high	95.5	Very high	26 Å²	26	34.9 Å²	34.9	10%	0.102	17%	0.171	C	C	.	.	H	α-helix	trans	-65.3	-37.3	178.6	-63	-14.7	0	0	0	112.5	I63 R296 V298 F302 L303 I304	I63-Y300 HydrophobicContact CD1-CD1 4.33Å; I63-Y300 HydrophobicContact CD1-CE1 3.54Å; I63-Y300 HydrophobicContact CG1-CD1 4.28Å; I63-Y300 HydrophobicContact CG1-CE1 3.82Å; I63-Y300 HydrophobicContact CG1-CE2 4.11Å; R296-Y300 HydrophobicContact CB-CD1 4.37Å; R296-Y300 HydrophobicContact CB-CE1 3.97Å; R296-Y300 HydrophobicContact CB-CE2 4.45Å; R296-Y300 WeakPolarHBondContact O-CB 3.46Å; R296-Y300 WeakPolarHBondContact O-CD1 3.18Å; R296-Y300 WeakPolarHBondContact O-CD2 3.24Å; R296-Y300 PolarHBondContact O-N 3.32Å; V298-Y300 VanDerWaalsContact C-N 3.32Å; V298-Y300 PolarHBondContact O-N 2.92Å; Y300-F302 PolarHBondContact O-N 3.23Å; Y300-L303 PolarHBondContact O-N 2.92Å; Y300-I304 HydrophobicContact CG-CD1 4.47Å; Y300-I304 WeakPolarHBondContact O-CB 3.49Å; Y300-I304 PolarHBondContact O-N 2.9Å
301	S	97.6	Very high	95.7	Very high	0 Å²	0	34.7 Å²	34.7	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-63.8	-20.6	176.6	-59.1	0	0	0	0	113.2	I108 I112 Y115 I297 V298 S299 P305	I108-S301 WeakPolarHBondContact CG1-O 3.47Å; I112-S301 WeakPolarHBondContact CA-OG 3.18Å; I112-S301 VanDerWaalsContact CG1-CB 3.42Å; Y115-S301 WeakPolarHBondContact CD2-OG 3.44Å; I297-S301 VanDerWaalsContact O-CB 3.3Å; I297-S301 WeakPolarHBondContact O-CB 3.32Å; I297-S301 PolarHBondContact O-N 3.31Å; I297-S301 PolarHBondContact O-OG 2.96Å; V298-S301 WeakPolarHBondContact O-CB 3.49Å; V298-S301 PolarHBondContact O-N 3.02Å; V298-S301 VanDerWaalsContact O-N 3.17Å; S299-S301 PolarHBondContact O-N 3.49Å; S301-P305 WeakPolarHBondContact O-CD 3.26Å; S301-P305 WeakPolarHBondContact O-CG 3.38Å
302	F	97.4	Very high	95.9	Very high	77 Å²	77	34.4 Å²	34.4	34%	0.338	17%	0.169	S	C	.	.	H	α-helix	trans	-93.8	-50.9	170.3	-77.4	-100.9	0	0	0	111.5	F104 I108 I112 V298 S299 Y300 I304 P305 I306	F104-F302 HydrophobicContact CD1-CD1 4.42Å; F104-F302 HydrophobicContact CD1-CE1 4.17Å; F104-F302 HydrophobicContact CE1-CD1 4.13Å; F104-F302 HydrophobicContact CE1-CE1 4.27Å; I108-F302 HydrophobicContact CD1-CD1 3.73Å; I108-F302 HydrophobicContact CD1-CE1 4.12Å; I108-F302 HydrophobicContact CD1-CG 4.22Å; I108-F302 HydrophobicContact CG2-CD1 4.1Å; I108-F302 HydrophobicContact CG2-CD2 3.92Å; I108-F302 HydrophobicContact CG2-CE1 3.88Å; I108-F302 HydrophobicContact CG2-CE2 3.69Å; I108-F302 HydrophobicContact CG2-CG 4.12Å; I108-F302 HydrophobicContact CG2-CZ 3.67Å; I112-F302 HydrophobicContact CD1-CE2 4.07Å; V298-F302 HydrophobicContact CG1-CE2 4.34Å; V298-F302 WeakPolarHBondContact O-CD2 3.47Å; V298-F302 PolarHBondContact O-N 3.3Å; S299-F302 PolarHBondContact O-N 2.87Å; Y300-F302 PolarHBondContact O-N 3.23Å; F302-I304 PolarHBondContact O-N 3.4Å; F302-P305 WeakPolarHBondContact O-CD 3.42Å; F302-I306 WeakPolarHBondContact O-CB 3.17Å; F302-I306 VanDerWaalsContact O-CD1 3.31Å; F302-I306 WeakPolarHBondContact O-CD1 3Å; F302-I306 WeakPolarHBondContact O-CG1 3.48Å; F302-I306 PolarHBondContact O-N 2.97Å
303	L	97.2	Very high	96.3	Very high	86 Å²	86	34.5 Å²	34.5	45%	0.45	17%	0.167	S	C	.	.	H	α-helix	trans	-60.8	-48.8	-171.5	179	63.4	0	0	0	112.6	S299 Y300 I306 I307	S299-L303 WeakPolarHBondContact O-CB 3.35Å; S299-L303 PolarHBondContact O-N 2.95Å; Y300-L303 PolarHBondContact O-N 2.92Å; L303-I306 PolarHBondContact O-N 2.86Å; L303-I307 HydrophobicContact CD1-CD1 3.97Å; L303-I307 HydrophobicContact CD1-CG1 4.33Å; L303-I307 HydrophobicContact CG-CD1 3.86Å; L303-I307 WeakPolarHBondContact O-CG1 3.47Å; L303-I307 PolarHBondContact O-N 3.39Å
304	I	97.5	Very high	96.7	Very high	2 Å²	2	35 Å²	35	1%	0.01	17%	0.169	C	C	.	.	H	α-helix	trans	-66.7	-49.7	-172.7	-67.2	168	0	0	0	112.1	I63 C66 V67 A70 Y115 Y300 F302 I306 I307 N308	I63-I304 HydrophobicContact CG2-CD1 4.37Å; I63-I304 HydrophobicContact CG2-CG1 4.46Å; C66-I304 HydrophobicContact CB-CD1 3.58Å; V67-I304 HydrophobicContact CG2-CG1 4.19Å; V67-I304 HydrophobicContact CG2-CG2 4.18Å; A70-I304 HydrophobicContact CB-CG2 4.1Å; Y115-I304 WeakPolarHBondContact OH-CD1 3.2Å; Y300-I304 HydrophobicContact CG-CD1 4.47Å; Y300-I304 WeakPolarHBondContact O-CB 3.49Å; Y300-I304 PolarHBondContact O-N 2.9Å; F302-I304 PolarHBondContact O-N 3.4Å; I304-I306 VanDerWaalsContact C-N 3.26Å; I304-I306 PolarHBondContact O-N 3.46Å; I304-I307 PolarHBondContact O-N 3.45Å; I304-N308 WeakPolarHBondContact O-CB 3.31Å; I304-N308 PolarHBondContact O-N 2.93Å
305	P	97.6	Very high	97	Very high	1 Å²	1	31.4 Å²	31.4	1%	0.006	15%	0.151	C	C	.	.	H	α-helix	trans	-71.5	-20.5	177.9	32	-39.2	0	0	0	113.1	L103 I108 L111 T277 S301 F302 N308 N309	L103-P305 HydrophobicContact CD1-CB 3.68Å; L103-P305 HydrophobicContact CD1-CG 4.17Å; I108-P305 HydrophobicContact CG1-CG 3.94Å; L111-P305 HydrophobicContact CD1-CB 3.75Å; L111-P305 HydrophobicContact CD1-CG 3.7Å; T277-P305 HydrophobicContact CG2-CB 3.68Å; S301-P305 WeakPolarHBondContact O-CD 3.26Å; S301-P305 WeakPolarHBondContact O-CG 3.38Å; F302-P305 WeakPolarHBondContact O-CD 3.42Å; P305-N308 WeakPolarHBondContact O-CB 3.32Å; P305-N309 WeakPolarHBondContact O-CB 3.47Å; P305-N309 PolarHBondContact O-N 3.02Å; P305-N309 PolarHBondContact O-OD1 3.32Å
306	I	97.9	Very high	97.2	Very high	60 Å²	60	30.6 Å²	30.6	31%	0.308	15%	0.145	S	C	.	.	H	α-helix	trans	-68.1	-47.8	167.5	-71.8	168.4	0	0	0	110.8	L103 F104 F302 L303 I304 N308 N309 L310	L103-I306 HydrophobicContact CD2-CG1 4.03Å; F104-I306 HydrophobicContact CE1-CD1 4.47Å; F104-I306 HydrophobicContact CZ-CD1 4.29Å; F302-I306 WeakPolarHBondContact O-CB 3.17Å; F302-I306 VanDerWaalsContact O-CD1 3.31Å; F302-I306 WeakPolarHBondContact O-CD1 3Å; F302-I306 WeakPolarHBondContact O-CG1 3.48Å; F302-I306 PolarHBondContact O-N 2.97Å; L303-I306 PolarHBondContact O-N 2.86Å; I304-I306 VanDerWaalsContact C-N 3.26Å; I304-I306 PolarHBondContact O-N 3.46Å; I306-N308 VanDerWaalsContact C-N 3.26Å; I306-N308 PolarHBondContact O-N 3.46Å; I306-N309 PolarHBondContact O-N 3.19Å; I306-L310 HydrophobicContact CG2-CD1 4.32Å; I306-L310 WeakPolarHBondContact O-CG 3.01Å; I306-L310 PolarHBondContact O-N 2.97Å
307	I	97.2	Very high	97.4	Very high	48 Å²	48	25.6 Å²	25.6	25%	0.246	13%	0.127	C	C	.	.	H	α-helix	trans	-56.3	-45.4	174.3	-70.2	166.4	0	0	0	110.1	V67 L303 I304 N309 L310 V311	V67-I307 HydrophobicContact CG1-CG2 4.26Å; L303-I307 HydrophobicContact CD1-CD1 3.97Å; L303-I307 HydrophobicContact CD1-CG1 4.33Å; L303-I307 HydrophobicContact CG-CD1 3.86Å; L303-I307 WeakPolarHBondContact O-CG1 3.47Å; L303-I307 PolarHBondContact O-N 3.39Å; I304-I307 PolarHBondContact O-N 3.45Å; I307-N309 PolarHBondContact O-N 3.38Å; I307-L310 WeakPolarHBondContact O-CB 3.05Å; I307-L310 PolarHBondContact O-N 3.19Å; I307-L310 VanDerWaalsContact O-N 3.16Å; I307-V311 PolarHBondContact O-N 2.9Å
308	N	97.5	Very high	97.5	Very high	0 Å²	0	25.9 Å²	25.9	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-55	-48.7	175.7	177.5	79.3	0	0	0	113	A70 V71 N75 D276 I304 P305 I306 L310 V311 S312	A70-N308 VanDerWaalsContact C-OD1 3.23Å; A70-N308 HydrophobicContact CB-CB 4.27Å; A70-N308 PolarHBondContact O-OD1 3.02Å; A70-N308 VanDerWaalsContact O-OD1 3.14Å; V71-N308 WeakPolarHBondContact CA-OD1 3.48Å; V71-N308 HydrophobicContact CG2-CB 4.3Å; V71-N308 PolarHBondContact N-OD1 3.08Å; N75-N308 VanDerWaalsContact ND2-CG 3.26Å; N75-N308 PolarHBondContact ND2-ND2 3.35Å; N75-N308 PolarHBondContact ND2-O 3.11Å; N75-N308 PolarHBondContact ND2-OD1 3.48Å; D276-N308 PolarHBondContact O-ND2 3.09Å; D276-N308 PolarHBondContact O-OD1 2.84Å; I304-N308 WeakPolarHBondContact O-CB 3.31Å; I304-N308 PolarHBondContact O-N 2.93Å; P305-N308 WeakPolarHBondContact O-CB 3.32Å; I306-N308 VanDerWaalsContact C-N 3.26Å; I306-N308 PolarHBondContact O-N 3.46Å; N308-L310 VanDerWaalsContact C-N 3.33Å; N308-L310 PolarHBondContact O-N 3.05Å; N308-V311 WeakPolarHBondContact O-CB 3.44Å; N308-V311 PolarHBondContact O-N 3.02Å; N308-S312 PolarHBondContact O-N 3.47Å; N308-S312 VanDerWaalsContact O-N 3.14Å
309	N	97.7	Very high	97.4	Very high	9 Å²	9	26 Å²	26	5%	0.048	13%	0.129	C	C	.	.	H	α-helix	trans	-67.1	-34.4	177.6	-82.2	21.6	0	0	0	111.8	W99 L103 N273 P305 I306 I307 V311 S312 L313	W99-N309 VanDerWaalsContact CH2-CA 3.5Å; W99-N309 HydrophobicContact CH2-CB 3.29Å; W99-N309 WeakPolarHBondContact CH2-ND2 3.34Å; W99-N309 WeakPolarHBondContact CH2-O 3.35Å; W99-N309 HydrophobicContact CZ2-CB 3.68Å; W99-N309 VanDerWaalsContact CZ2-ND2 3.33Å; W99-N309 WeakPolarHBondContact CZ2-ND2 3.15Å; W99-N309 VanDerWaalsContact CZ2-OD1 3.25Å; W99-N309 WeakPolarHBondContact CZ2-OD1 3.05Å; W99-N309 HydrophobicContact CZ3-CB 3.99Å; L103-N309 HydrophobicContact CD2-CB 4.47Å; L103-N309 WeakPolarHBondContact CD2-ND2 3.47Å; N273-N309 PolarHBondContact ND2-ND2 3.43Å; N273-N309 VanDerWaalsContact ND2-ND2 3.19Å; P305-N309 WeakPolarHBondContact O-CB 3.47Å; P305-N309 PolarHBondContact O-N 3.02Å; P305-N309 PolarHBondContact O-OD1 3.32Å; I306-N309 PolarHBondContact O-N 3.19Å; I307-N309 PolarHBondContact O-N 3.38Å; N309-V311 VanDerWaalsContact C-N 3.27Å; N309-V311 PolarHBondContact O-N 3.42Å; N309-S312 PolarHBondContact O-N 2.59Å; N309-L313 WeakPolarHBondContact O-CB 3.27Å; N309-L313 PolarHBondContact O-N 3.21Å
310	L	97.6	Very high	97.3	Very high	71 Å²	71	24.9 Å²	24.9	37%	0.372	12%	0.122	S	C	.	.	H	α-helix	trans	-61.9	-37.4	172.4	-71.3	172.4	0	0	0	111.7	I306 I307 N308 L313 Y314	I306-L310 HydrophobicContact CG2-CD1 4.32Å; I306-L310 WeakPolarHBondContact O-CG 3.01Å; I306-L310 PolarHBondContact O-N 2.97Å; I307-L310 WeakPolarHBondContact O-CB 3.05Å; I307-L310 PolarHBondContact O-N 3.19Å; I307-L310 VanDerWaalsContact O-N 3.16Å; N308-L310 VanDerWaalsContact C-N 3.33Å; N308-L310 PolarHBondContact O-N 3.05Å; L310-L313 HydrophobicContact CD2-CD2 4.39Å; L310-L313 PolarHBondContact O-N 3.23Å; L310-Y314 HydrophobicContact CB-CE2 4.35Å; L310-Y314 WeakPolarHBondContact O-CB 3.3Å; L310-Y314 VanDerWaalsContact O-CD2 3.26Å; L310-Y314 WeakPolarHBondContact O-CD2 3.35Å; L310-Y314 VanDerWaalsContact O-CG 3.3Å; L310-Y314 PolarHBondContact O-N 2.91Å
311	V	97.9	Very high	97.4	Very high	4 Å²	4	23.7 Å²	23.7	2%	0.024	12%	0.117	C	C	.	.	H	α-helix	trans	-60.9	-49	172.9	170.7	0	0	0	0	111.3	V71 N75 L229 I232 I307 N308 N309 L313 Y314 A315	V71-V311 HydrophobicContact CG1-CB 4.39Å; V71-V311 HydrophobicContact CG1-CG1 3.81Å; V71-V311 HydrophobicContact CG1-CG2 4.41Å; V71-V311 HydrophobicContact CG2-CB 4.48Å; V71-V311 HydrophobicContact CG2-CG2 4.17Å; N75-V311 HydrophobicContact CB-CG1 4.22Å; L229-V311 HydrophobicContact CD2-CG2 3.52Å; I232-V311 HydrophobicContact CD1-CG1 3.43Å; I232-V311 VanDerWaalsContact CD1-CG1 3.43Å; I307-V311 PolarHBondContact O-N 2.9Å; N308-V311 WeakPolarHBondContact O-CB 3.44Å; N308-V311 PolarHBondContact O-N 3.02Å; N309-V311 VanDerWaalsContact C-N 3.27Å; N309-V311 PolarHBondContact O-N 3.42Å; V311-L313 VanDerWaalsContact C-N 3.31Å; V311-L313 PolarHBondContact O-N 3.37Å; V311-Y314 PolarHBondContact O-N 2.73Å; V311-A315 WeakPolarHBondContact O-CB 3.44Å; V311-A315 PolarHBondContact O-N 3.46Å
312	S	97.7	Very high	97.3	Very high	0 Å²	0	23.7 Å²	23.7	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-60	-40.8	176.4	-59.7	0	0	0	0	112.2	N75 F79 N308 N309 A315 S316	N75-S312 WeakPolarHBondContact CB-OG 3.16Å; N75-S312 PolarHBondContact ND2-OG 2.93Å; F79-S312 VanDerWaalsContact CD1-O 3.27Å; F79-S312 WeakPolarHBondContact CD1-O 3.29Å; F79-S312 WeakPolarHBondContact CE1-O 3.44Å; N308-S312 PolarHBondContact O-N 3.47Å; N308-S312 VanDerWaalsContact O-N 3.14Å; N309-S312 PolarHBondContact O-N 2.59Å; S312-A315 PolarHBondContact O-N 2.95Å; S312-S316 PolarHBondContact O-N 2.89Å; S312-S316 PolarHBondContact O-OG 3.4Å
313	L	97.9	Very high	97.2	Very high	37 Å²	37	20 Å²	20	19%	0.194	10%	0.101	C	C	.	.	H	α-helix	trans	-61.9	-52.1	176.2	179.8	62.8	0	0	0	111.2	Y96 F253 N309 L310 V311 A315 S316 I317	Y96-L313 HydrophobicContact CD1-CD1 4.46Å; Y96-L313 HydrophobicContact CE1-CD1 3.83Å; Y96-L313 HydrophobicContact CE2-CD1 4.01Å; F253-L313 HydrophobicContact CZ-CD1 4.4Å; N309-L313 WeakPolarHBondContact O-CB 3.27Å; N309-L313 PolarHBondContact O-N 3.21Å; L310-L313 HydrophobicContact CD2-CD2 4.39Å; L310-L313 PolarHBondContact O-N 3.23Å; V311-L313 VanDerWaalsContact C-N 3.31Å; V311-L313 PolarHBondContact O-N 3.37Å; L313-A315 VanDerWaalsContact C-N 3.33Å; L313-A315 PolarHBondContact O-N 2.59Å; L313-S316 PolarHBondContact O-N 3.46Å; L313-S316 PolarHBondContact O-OG 2.89Å; L313-I317 HydrophobicContact CD1-CD1 4.03Å; L313-I317 HydrophobicContact CD1-CG1 4.42Å; L313-I317 HydrophobicContact CG-CD1 4Å; L313-I317 WeakPolarHBondContact O-CG1 3.48Å; L313-I317 PolarHBondContact O-N 3.26Å
314	Y	98.1	Very high	97.1	Very high	72 Å²	72	16 Å²	16	28%	0.282	8%	0.08	S	C	.	.	H	α-helix	trans	-62.4	-38.8	178.3	-66.6	-34.2	0	0	0	112.5	L233 F236 L310 V311 I317 T318	L233-Y314 HydrophobicContact CD2-CD2 3.92Å; L233-Y314 HydrophobicContact CD2-CE2 3.79Å; F236-Y314 HydrophobicContact CD1-CD1 4.37Å; F236-Y314 AromaticContact CD2-CD1 3.86Å; F236-Y314 HydrophobicContact CD2-CD1 3.86Å; F236-Y314 HydrophobicContact CD2-CG 4.32Å; F236-Y314 HydrophobicContact CE1-CD1 4.25Å; F236-Y314 HydrophobicContact CE1-CE1 4.27Å; F236-Y314 AromaticContact CE2-CD1 3.71Å; F236-Y314 HydrophobicContact CE2-CD1 3.71Å; F236-Y314 HydrophobicContact CE2-CE1 4.32Å; F236-Y314 HydrophobicContact CG-CD1 4.19Å; F236-Y314 HydrophobicContact CG-CG 4.42Å; F236-Y314 AromaticContact CZ-CD1 3.93Å; F236-Y314 HydrophobicContact CZ-CD1 3.93Å; F236-Y314 HydrophobicContact CZ-CE1 4.08Å; L310-Y314 HydrophobicContact CB-CE2 4.35Å; L310-Y314 WeakPolarHBondContact O-CB 3.3Å; L310-Y314 VanDerWaalsContact O-CD2 3.26Å; L310-Y314 WeakPolarHBondContact O-CD2 3.35Å; L310-Y314 VanDerWaalsContact O-CG 3.3Å; L310-Y314 PolarHBondContact O-N 2.91Å; V311-Y314 PolarHBondContact O-N 2.73Å; Y314-I317 PolarHBondContact O-N 2.94Å; Y314-T318 VanDerWaalsContact O-CB 3.3Å; Y314-T318 WeakPolarHBondContact O-CB 3.08Å; Y314-T318 PolarHBondContact O-N 3.28Å; Y314-T318 PolarHBondContact O-OG1 2.89Å
315	A	97.3	Very high	97	Very high	5 Å²	5	15.9 Å²	15.9	4%	0.041	8%	0.079	C	C	.	.	H	α-helix	trans	-60.7	-48.9	173.8	0	0	0	0	0	111.3	I76 V311 S312 L313 I317 T318 I319	I76-A315 HydrophobicContact CB-CB 4.48Å; I76-A315 HydrophobicContact CG2-CB 4.44Å; V311-A315 WeakPolarHBondContact O-CB 3.44Å; V311-A315 PolarHBondContact O-N 3.46Å; S312-A315 PolarHBondContact O-N 2.95Å; L313-A315 VanDerWaalsContact C-N 3.33Å; L313-A315 PolarHBondContact O-N 2.59Å; A315-I317 PolarHBondContact O-N 3.36Å; A315-T318 WeakPolarHBondContact O-CB 3.48Å; A315-T318 PolarHBondContact O-N 3.07Å; A315-I319 WeakPolarHBondContact O-CG1 3.49Å; A315-I319 PolarHBondContact O-N 3.42Å
316	S	96.7	Very high	96.8	Very high	0 Å²	0	16 Å²	16	0%	0	8%	0.08	C	C	.	.	H	α-helix	trans	-62.5	-42.2	178.3	61.1	0	0	0	0	113.2	Y96 S312 L313 T318 I319 F320	Y96-S316 PolarHBondContact OH-OG 3.06Å; S312-S316 PolarHBondContact O-N 2.89Å; S312-S316 PolarHBondContact O-OG 3.4Å; L313-S316 PolarHBondContact O-N 3.46Å; L313-S316 PolarHBondContact O-OG 2.89Å; S316-T318 PolarHBondContact O-N 3.12Å; S316-I319 PolarHBondContact O-N 3.16Å; S316-F320 WeakPolarHBondContact O-CB 3.29Å; S316-F320 WeakPolarHBondContact O-CD2 3.3Å; S316-F320 PolarHBondContact O-N 3.14Å
317	I	98	Very high	96.6	Very high	13 Å²	13	14.2 Å²	14.2	7%	0.067	7%	0.071	C	C	.	.	H	α-helix	trans	-61.3	-47.3	174.7	-64.8	165.8	0	0	0	110.5	F236 I240 I249 L252 F253 L313 Y314 A315 I319 F320 S321	F236-I317 HydrophobicContact CD2-CB 4.18Å; F236-I317 HydrophobicContact CD2-CG2 4.05Å; F236-I317 HydrophobicContact CE2-CB 3.88Å; F236-I317 HydrophobicContact CE2-CD1 3.95Å; F236-I317 HydrophobicContact CE2-CG2 3.58Å; I240-I317 HydrophobicContact CG2-CG2 3.98Å; I249-I317 HydrophobicContact CD1-CG2 4.49Å; I249-I317 HydrophobicContact CG1-CG2 4.04Å; L252-I317 HydrophobicContact CD1-CB 4.25Å; L252-I317 HydrophobicContact CD1-CG1 3.77Å; F253-I317 HydrophobicContact CE2-CD1 4.17Å; F253-I317 HydrophobicContact CE2-CG1 4.43Å; F253-I317 HydrophobicContact CZ-CD1 4.28Å; L313-I317 HydrophobicContact CD1-CD1 4.03Å; L313-I317 HydrophobicContact CD1-CG1 4.42Å; L313-I317 HydrophobicContact CG-CD1 4Å; L313-I317 WeakPolarHBondContact O-CG1 3.48Å; L313-I317 PolarHBondContact O-N 3.26Å; Y314-I317 PolarHBondContact O-N 2.94Å; A315-I317 PolarHBondContact O-N 3.36Å; I317-I319 VanDerWaalsContact C-N 3.31Å; I317-I319 PolarHBondContact O-N 3.25Å; I317-F320 PolarHBondContact O-N 3.48Å; I317-S321 VanDerWaalsContact O-CB 3.23Å; I317-S321 WeakPolarHBondContact O-CB 3.16Å; I317-S321 PolarHBondContact O-N 2.84Å; I317-S321 PolarHBondContact O-OG 3.37Å; I317-S321 VanDerWaalsContact O-OG 3.06Å
318	T	97.5	Very high	96.5	Very high	6 Å²	6	13 Å²	13	4%	0.037	7%	0.065	C	C	.	.	H	α-helix	trans	-54.6	-48.2	177.9	-59.1	0	0	0	0	111.4	M235 F236 A239 Y314 A315 S316 T322	M235-T318 HydrophobicContact CB-CG2 3.99Å; M235-T318 HydrophobicContact CE-CG2 4.37Å; F236-T318 VanDerWaalsContact CA-OG1 3.23Å; F236-T318 WeakPolarHBondContact CA-OG1 3.4Å; F236-T318 WeakPolarHBondContact CB-OG1 3.39Å; A239-T318 HydrophobicContact CB-CG2 3.86Å; Y314-T318 VanDerWaalsContact O-CB 3.3Å; Y314-T318 WeakPolarHBondContact O-CB 3.08Å; Y314-T318 PolarHBondContact O-N 3.28Å; Y314-T318 PolarHBondContact O-OG1 2.89Å; A315-T318 WeakPolarHBondContact O-CB 3.48Å; A315-T318 PolarHBondContact O-N 3.07Å; S316-T318 PolarHBondContact O-N 3.12Å; T318-T322 VanDerWaalsContact O-CB 3.29Å; T318-T322 WeakPolarHBondContact O-CB 3.29Å; T318-T322 PolarHBondContact O-N 3.08Å; T318-T322 PolarHBondContact O-OG1 3.43Å
319	I	95.3	Very high	96.3	Very high	6 Å²	6	17.4 Å²	17.4	3%	0.031	9%	0.085	C	C	.	.	H	α-helix	trans	-68.4	-48.8	-177	-64.4	-71.5	0	0	0	111	P80 A315 S316 I317 T322 V323 L353 I358 F376	P80-I319 HydrophobicContact CB-CB 4.09Å; P80-I319 HydrophobicContact CB-CG1 4.26Å; P80-I319 HydrophobicContact CB-CG2 4.08Å; P80-I319 HydrophobicContact CG-CB 4.36Å; P80-I319 HydrophobicContact CG-CG1 4.03Å; A315-I319 WeakPolarHBondContact O-CG1 3.49Å; A315-I319 PolarHBondContact O-N 3.42Å; S316-I319 PolarHBondContact O-N 3.16Å; I317-I319 VanDerWaalsContact C-N 3.31Å; I317-I319 PolarHBondContact O-N 3.25Å; I319-T322 PolarHBondContact O-N 3.42Å; I319-V323 HydrophobicContact CG2-CG2 4.16Å; I319-V323 WeakPolarHBondContact O-CB 3.45Å; I319-V323 WeakPolarHBondContact O-CG2 3.48Å; I319-V323 PolarHBondContact O-N 2.93Å; I319-L353 HydrophobicContact CG2-CD1 4.43Å; I319-L353 HydrophobicContact CG2-CD2 4.06Å; I319-I358 HydrophobicContact CD1-CD1 3.45Å; I319-I358 VanDerWaalsContact CD1-CD1 3.45Å; I319-I358 HydrophobicContact CD1-CG1 4.3Å; I319-F376 HydrophobicContact CD1-CE2 3.84Å; I319-F376 HydrophobicContact CD1-CZ 4.1Å
320	F	95.8	Very high	95.9	Very high	0 Å²	0	21 Å²	21	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-64.3	-44.2	179.3	-83.2	-112.2	0	0	0	111.6	P80 L83 A84 F251 L252 S316 I317 T322 V323 F324 I343	P80-F320 HydrophobicContact CB-CE2 4.41Å; L83-F320 HydrophobicContact CD2-CE2 4.18Å; L83-F320 HydrophobicContact CD2-CZ 4.39Å; A84-F320 HydrophobicContact CB-CE2 4.46Å; A84-F320 HydrophobicContact CB-CZ 3.81Å; F251-F320 AromaticContact CD1-CD1 3.92Å; F251-F320 HydrophobicContact CD1-CD1 3.92Å; F251-F320 AromaticContact CD1-CE1 3.59Å; F251-F320 HydrophobicContact CD1-CE1 3.59Å; F251-F320 HydrophobicContact CE1-CD1 4.43Å; F251-F320 AromaticContact CE1-CE1 3.65Å; F251-F320 HydrophobicContact CE1-CE1 3.65Å; L252-F320 HydrophobicContact CD1-CB 3.81Å; L252-F320 HydrophobicContact CD1-CD2 4.42Å; L252-F320 HydrophobicContact CD1-CG 4.02Å; L252-F320 HydrophobicContact CD2-CB 4.4Å; L252-F320 HydrophobicContact CD2-CD1 3.68Å; L252-F320 HydrophobicContact CD2-CD2 3.86Å; L252-F320 HydrophobicContact CD2-CE1 3.79Å; L252-F320 HydrophobicContact CD2-CE2 3.93Å; L252-F320 HydrophobicContact CD2-CG 3.71Å; L252-F320 HydrophobicContact CD2-CZ 3.89Å; L252-F320 HydrophobicContact CG-CB 4.07Å; L252-F320 HydrophobicContact CG-CD1 3.91Å; L252-F320 HydrophobicContact CG-CD2 4.44Å; L252-F320 HydrophobicContact CG-CE1 4.47Å; L252-F320 HydrophobicContact CG-CG 3.89Å; S316-F320 WeakPolarHBondContact O-CB 3.29Å; S316-F320 WeakPolarHBondContact O-CD2 3.3Å; S316-F320 PolarHBondContact O-N 3.14Å; I317-F320 PolarHBondContact O-N 3.48Å; F320-T322 VanDerWaalsContact C-N 3.33Å; F320-T322 PolarHBondContact O-N 3.16Å; F320-V323 PolarHBondContact O-N 3.06Å; F320-F324 HydrophobicContact CD1-CD2 4.44Å; F320-F324 AromaticContact CD1-CE2 3.85Å; F320-F324 HydrophobicContact CD1-CE2 3.85Å; F320-F324 WeakPolarHBondContact O-CB 3.23Å; F320-F324 WeakPolarHBondContact O-CD2 3.34Å; F320-F324 PolarHBondContact O-N 3.05Å; F320-I343 HydrophobicContact CD1-CD1 3.76Å; F320-I343 HydrophobicContact CD2-CD1 4.24Å; F320-I343 HydrophobicContact CE1-CD1 3.76Å; F320-I343 HydrophobicContact CE2-CD1 4.28Å; F320-I343 HydrophobicContact CE2-CG2 4.17Å; F320-I343 HydrophobicContact CG-CD1 4.01Å; F320-I343 HydrophobicContact CZ-CD1 4.06Å; F320-I343 HydrophobicContact CZ-CG2 4.24Å
321	S	97.2	Very high	95.6	Very high	0 Å²	0	21.1 Å²	21.1	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-58.2	-45.5	174.8	-68.6	0	0	0	0	111.7	I249 I317 S325	I249-S321 WeakPolarHBondContact CG1-OG 3.35Å; I317-S321 VanDerWaalsContact O-CB 3.23Å; I317-S321 WeakPolarHBondContact O-CB 3.16Å; I317-S321 PolarHBondContact O-N 2.84Å; I317-S321 PolarHBondContact O-OG 3.37Å; I317-S321 VanDerWaalsContact O-OG 3.06Å; S321-S325 WeakPolarHBondContact O-CB 3.15Å; S321-S325 PolarHBondContact O-N 3.02Å
322	T	95.8	Very high	95.3	Very high	1 Å²	1	26.1 Å²	26.1	1%	0.006	14%	0.141	C	C	.	.	H	α-helix	trans	-65.7	-46.3	-179.8	-56.9	0	0	0	0	111.9	W238 T318 I319 F320 T326 F362	W238-T322 HydrophobicContact CH2-CG2 4.19Å; W238-T322 HydrophobicContact CZ3-CG2 4.13Å; T318-T322 VanDerWaalsContact O-CB 3.29Å; T318-T322 WeakPolarHBondContact O-CB 3.29Å; T318-T322 PolarHBondContact O-N 3.08Å; T318-T322 PolarHBondContact O-OG1 3.43Å; I319-T322 PolarHBondContact O-N 3.42Å; F320-T322 VanDerWaalsContact C-N 3.33Å; F320-T322 PolarHBondContact O-N 3.16Å; T322-T326 VanDerWaalsContact O-CB 3.29Å; T322-T326 WeakPolarHBondContact O-CB 3.46Å; T322-T326 PolarHBondContact O-N 3.25Å; T322-T326 PolarHBondContact O-OG1 2.95Å; T322-F362 HydrophobicContact CG2-CE1 4Å
323	V	94.7	Very high	95	Very high	0 Å²	0	32 Å²	32	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-65.2	-50.8	-178.9	176.8	0	0	0	0	110.5	I319 F320 S325 T326 I327 V339 L342 I343 L353 L361	I319-V323 HydrophobicContact CG2-CG2 4.16Å; I319-V323 WeakPolarHBondContact O-CB 3.45Å; I319-V323 WeakPolarHBondContact O-CG2 3.48Å; I319-V323 PolarHBondContact O-N 2.93Å; F320-V323 PolarHBondContact O-N 3.06Å; V323-S325 PolarHBondContact O-N 3.14Å; V323-T326 PolarHBondContact O-N 2.77Å; V323-I327 HydrophobicContact CG1-CG1 4.17Å; V323-I327 WeakPolarHBondContact O-CB 3.39Å; V323-I327 VanDerWaalsContact O-CG1 3.24Å; V323-I327 WeakPolarHBondContact O-CG1 3.37Å; V323-I327 PolarHBondContact O-N 2.89Å; V323-V339 HydrophobicContact CG1-CG1 3.74Å; V323-L342 HydrophobicContact CG1-CD2 3.95Å; V323-I343 HydrophobicContact CB-CD1 4.18Å; V323-I343 HydrophobicContact CB-CG1 4.24Å; V323-I343 HydrophobicContact CG1-CD1 4.05Å; V323-I343 HydrophobicContact CG1-CG1 3.77Å; V323-I343 HydrophobicContact CG2-CD1 4.43Å; V323-I343 HydrophobicContact CG2-CG1 4.2Å; V323-L353 HydrophobicContact CG2-CD1 4.46Å; V323-L361 HydrophobicContact CB-CD1 4.39Å; V323-L361 HydrophobicContact CG2-CD1 3.55Å
324	F	95.3	Very high	94.7	Very high	0 Å²	0	31.8 Å²	31.8	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-61.6	-46	179.2	-85	-103.8	0	0	0	111.5	I247 F251 F320 T326 I328 R336 V339 V340 I343	I247-F324 HydrophobicContact CB-CD1 4.15Å; I247-F324 HydrophobicContact CG2-CD1 3.68Å; I247-F324 HydrophobicContact CG2-CE1 3.91Å; F251-F324 HydrophobicContact CB-CZ 4.17Å; F251-F324 HydrophobicContact CG-CZ 4.21Å; F320-F324 HydrophobicContact CD1-CD2 4.44Å; F320-F324 AromaticContact CD1-CE2 3.85Å; F320-F324 HydrophobicContact CD1-CE2 3.85Å; F320-F324 WeakPolarHBondContact O-CB 3.23Å; F320-F324 WeakPolarHBondContact O-CD2 3.34Å; F320-F324 PolarHBondContact O-N 3.05Å; F324-T326 PolarHBondContact O-N 3.41Å; F324-I328 HydrophobicContact CB-CD1 4.46Å; F324-I328 HydrophobicContact CD1-CD1 4.21Å; F324-I328 VanDerWaalsContact O-CB 3.3Å; F324-I328 WeakPolarHBondContact O-CB 3.43Å; F324-I328 WeakPolarHBondContact O-CD1 3.44Å; F324-I328 WeakPolarHBondContact O-CG1 3.29Å; F324-I328 PolarHBondContact O-N 3.47Å; F324-I328 VanDerWaalsContact O-N 3.11Å; F324-R336 HydrophobicContact CE1-CB 4.31Å; F324-R336 HydrophobicContact CE1-CG 4.3Å; F324-V339 HydrophobicContact CB-CG1 4.45Å; F324-V339 HydrophobicContact CD1-CB 4.4Å; F324-V339 HydrophobicContact CD1-CG1 4Å; F324-V339 HydrophobicContact CD2-CG1 3.63Å; F324-V339 HydrophobicContact CE1-CB 4.21Å; F324-V339 HydrophobicContact CE1-CG1 4.14Å; F324-V339 HydrophobicContact CE2-CB 4.48Å; F324-V339 HydrophobicContact CE2-CG1 3.8Å; F324-V339 HydrophobicContact CG-CG1 3.77Å; F324-V339 HydrophobicContact CZ-CB 4.28Å; F324-V339 HydrophobicContact CZ-CG1 4.07Å; F324-V340 HydrophobicContact CE2-CG2 4.25Å; F324-V340 HydrophobicContact CZ-CG2 3.77Å; F324-I343 HydrophobicContact CD2-CD1 4.43Å; F324-I343 HydrophobicContact CE2-CD1 4.07Å
325	S	95.7	Very high	94.4	Very high	0 Å²	0	32.3 Å²	32.3	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-57.5	-49.8	178.4	-178.7	0	0	0	0	112.4	R242 Q243 S321 V323 Q329	R242-S325 VanDerWaalsContact CB-OG 3.26Å; R242-S325 WeakPolarHBondContact CB-OG 3.44Å; Q243-S325 WeakPolarHBondContact O-CA 3.22Å; Q243-S325 WeakPolarHBondContact O-CB 3.4Å; Q243-S325 PolarHBondContact O-OG 3.16Å; S321-S325 WeakPolarHBondContact O-CB 3.15Å; S321-S325 PolarHBondContact O-N 3.02Å; V323-S325 PolarHBondContact O-N 3.14Å; S325-Q329 WeakPolarHBondContact O-CB 3.01Å; S325-Q329 VanDerWaalsContact O-CG 3.27Å; S325-Q329 WeakPolarHBondContact O-CG 3.09Å; S325-Q329 PolarHBondContact O-N 2.96Å; S325-Q329 PolarHBondContact O-NE2 3.49Å; S325-Q329 VanDerWaalsContact O-NE2 3.14Å; S325-Q329 PolarHBondContact OG-NE2 2.95Å
326	T	94.6	Very high	93.9	Very high	4 Å²	4	39.6 Å²	39.6	3%	0.025	22%	0.215	C	C	.	.	H	α-helix	trans	-70.8	-46.6	-173.8	-52.9	0	0	0	0	111.2	T322 V323 F324 Q329 T330 L361 K364	T322-T326 VanDerWaalsContact O-CB 3.29Å; T322-T326 WeakPolarHBondContact O-CB 3.46Å; T322-T326 PolarHBondContact O-N 3.25Å; T322-T326 PolarHBondContact O-OG1 2.95Å; V323-T326 PolarHBondContact O-N 2.77Å; F324-T326 PolarHBondContact O-N 3.41Å; T326-Q329 PolarHBondContact O-N 2.98Å; T326-T330 WeakPolarHBondContact O-CG2 3.35Å; T326-T330 PolarHBondContact O-N 3.15Å; T326-T330 VanDerWaalsContact O-N 3.09Å; T326-T330 PolarHBondContact O-OG1 3.07Å; T326-L361 HydrophobicContact CG2-CD2 3.83Å; T326-K364 HydrophobicContact CG2-CB 3.91Å; T326-K364 HydrophobicContact CG2-CG 3.54Å
327	I	93.7	Very high	93.5	Very high	23 Å²	23	42.8 Å²	42.8	12%	0.118	24%	0.237	C	C	.	.	H	α-helix	trans	-68.6	-41.7	-175.1	-62.3	-64.6	0	0	0	111.3	V323 Q329 T330 N331 V334 V339 L342 W357 L361	V323-I327 HydrophobicContact CG1-CG1 4.17Å; V323-I327 WeakPolarHBondContact O-CB 3.39Å; V323-I327 VanDerWaalsContact O-CG1 3.24Å; V323-I327 WeakPolarHBondContact O-CG1 3.37Å; V323-I327 PolarHBondContact O-N 2.89Å; I327-Q329 PolarHBondContact O-N 3.27Å; I327-T330 WeakPolarHBondContact CA-OG1 3.5Å; I327-T330 PolarHBondContact O-N 2.99Å; I327-T330 PolarHBondContact O-OG1 3.48Å; I327-N331 PolarHBondContact O-N 3.4Å; I327-V334 HydrophobicContact CG2-CB 4.4Å; I327-V334 HydrophobicContact CG2-CG1 4.08Å; I327-V334 HydrophobicContact CG2-CG2 3.97Å; I327-V339 HydrophobicContact CB-CG2 4.35Å; I327-V339 HydrophobicContact CG2-CG2 3.93Å; I327-L342 HydrophobicContact CD1-CD1 3.67Å; I327-L342 HydrophobicContact CG1-CD1 4.06Å; I327-W357 HydrophobicContact CD1-CZ3 4.48Å; I327-L361 HydrophobicContact CD1-CD2 3.97Å; I327-L361 HydrophobicContact CG1-CD2 4.09Å
328	I	94.3	Very high	93.1	Very high	22 Å²	22	44.3 Å²	44.3	11%	0.113	25%	0.251	C	S	.	.	H	α-helix	trans	-64.9	-39.9	178.1	-66	171.6	0	0	0	111.3	Y244 I247 F324 T330 N331 P332 V334	Y244-I328 HydrophobicContact CD1-CG2 4.12Å; Y244-I328 HydrophobicContact CD2-CB 4.15Å; Y244-I328 HydrophobicContact CD2-CG2 3.69Å; Y244-I328 HydrophobicContact CE1-CG2 4.29Å; Y244-I328 HydrophobicContact CE2-CG2 3.89Å; Y244-I328 HydrophobicContact CG-CB 4.3Å; Y244-I328 HydrophobicContact CG-CG2 3.81Å; I247-I328 HydrophobicContact CB-CD1 4.49Å; I247-I328 HydrophobicContact CD1-CD1 3.76Å; I247-I328 HydrophobicContact CG2-CD1 4.44Å; F324-I328 HydrophobicContact CB-CD1 4.46Å; F324-I328 HydrophobicContact CD1-CD1 4.21Å; F324-I328 VanDerWaalsContact O-CB 3.3Å; F324-I328 WeakPolarHBondContact O-CB 3.43Å; F324-I328 WeakPolarHBondContact O-CD1 3.44Å; F324-I328 WeakPolarHBondContact O-CG1 3.29Å; F324-I328 PolarHBondContact O-N 3.47Å; F324-I328 VanDerWaalsContact O-N 3.11Å; I328-T330 VanDerWaalsContact C-N 3.33Å; I328-T330 PolarHBondContact O-N 3.28Å; I328-N331 CarbonylContact O-C 3.46Å; I328-N331 VanDerWaalsContact O-C 3.24Å; I328-N331 PolarHBondContact O-N 3.2Å; I328-P332 WeakPolarHBondContact O-CA 3.34Å; I328-V334 HydrophobicContact CB-CG1 4.42Å; I328-V334 HydrophobicContact CG1-CG1 3.77Å
329	Q	92.4	Very high	92.8	Very high	92 Å²	92	44 Å²	44	43%	0.43	25%	0.25	S	C	.	.	H	α-helix	trans	-64.3	-37.7	175.5	-76.2	177	63	0	0	112.5	Y244 S325 T326 I327	Y244-Q329 HydrophobicContact CD2-CG 3.93Å; Y244-Q329 HydrophobicContact CE2-CG 3.93Å; S325-Q329 WeakPolarHBondContact O-CB 3.01Å; S325-Q329 VanDerWaalsContact O-CG 3.27Å; S325-Q329 WeakPolarHBondContact O-CG 3.09Å; S325-Q329 PolarHBondContact O-N 2.96Å; S325-Q329 PolarHBondContact O-NE2 3.49Å; S325-Q329 VanDerWaalsContact O-NE2 3.14Å; S325-Q329 PolarHBondContact OG-NE2 2.95Å; T326-Q329 PolarHBondContact O-N 2.98Å; I327-Q329 PolarHBondContact O-N 3.27Å
330	T	90.8	Very high	92.5	Very high	85 Å²	85	44 Å²	44	52%	0.521	25%	0.25	S	C	.	.	H	α-helix	trans	-78.7	-26.6	178.8	57.3	0	0	0	0	113.8	T326 I327 I328	T326-T330 WeakPolarHBondContact O-CG2 3.35Å; T326-T330 PolarHBondContact O-N 3.15Å; T326-T330 VanDerWaalsContact O-N 3.09Å; T326-T330 PolarHBondContact O-OG1 3.07Å; I327-T330 WeakPolarHBondContact CA-OG1 3.5Å; I327-T330 PolarHBondContact O-N 2.99Å; I327-T330 PolarHBondContact O-OG1 3.48Å; I328-T330 VanDerWaalsContact C-N 3.33Å; I328-T330 PolarHBondContact O-N 3.28Å
331	N	91.6	Very high	92.2	Very high	74 Å²	74	51.2 Å²	51.2	40%	0.396	28%	0.281	S	S	.	.			trans	-144.1	87.5	179.8	-175.7	0.3	0	0	0	110.2	I327 I328 T333 V334	I327-N331 PolarHBondContact O-N 3.4Å; I328-N331 CarbonylContact O-C 3.46Å; I328-N331 VanDerWaalsContact O-C 3.24Å; I328-N331 PolarHBondContact O-N 3.2Å; N331-T333 PolarHBondContact O-N 3.43Å; N331-T333 VanDerWaalsContact O-N 3.08Å; N331-T333 PolarHBondContact OD1-N 3.12Å; N331-T333 PolarHBondContact OD1-OG1 3.25Å; N331-V334 HydrophobicContact CB-CB 4.31Å; N331-V334 VanDerWaalsContact O-CB 3.24Å; N331-V334 WeakPolarHBondContact O-CB 3.34Å; N331-V334 WeakPolarHBondContact O-CG1 3.25Å; N331-V334 PolarHBondContact O-N 3.47Å
332	P	90.1	Very high	91.7	Very high	109 Å²	109	52.1 Å²	52.1	71%	0.708	29%	0.286	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.2	-18.3	-174.6	-26.6	35.9	0	0	0	115.3	I328 V334	I328-P332 WeakPolarHBondContact O-CA 3.34Å; P332-V334 VanDerWaalsContact C-N 3.34Å
333	T	92.1	Very high	91.3	Very high	123 Å²	123	52 Å²	52	76%	0.755	29%	0.285	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90	0.5	178.4	63.4	0	0	0	0	113	N331	N331-T333 PolarHBondContact O-N 3.43Å; N331-T333 VanDerWaalsContact O-N 3.08Å; N331-T333 PolarHBondContact OD1-N 3.12Å; N331-T333 PolarHBondContact OD1-OG1 3.25Å
334	V	91.8	Very high	90.9	Very high	32 Å²	32	55.3 Å²	55.3	19%	0.194	30%	0.3	C	S	.	.			trans	-63.5	135.3	-179.3	73.9	0	0	0	0	111.6	I327 I328 N331 P332 A338 V339	I327-V334 HydrophobicContact CG2-CB 4.4Å; I327-V334 HydrophobicContact CG2-CG1 4.08Å; I327-V334 HydrophobicContact CG2-CG2 3.97Å; I328-V334 HydrophobicContact CB-CG1 4.42Å; I328-V334 HydrophobicContact CG1-CG1 3.77Å; N331-V334 HydrophobicContact CB-CB 4.31Å; N331-V334 VanDerWaalsContact O-CB 3.24Å; N331-V334 WeakPolarHBondContact O-CB 3.34Å; N331-V334 WeakPolarHBondContact O-CG1 3.25Å; N331-V334 PolarHBondContact O-N 3.47Å; P332-V334 VanDerWaalsContact C-N 3.34Å; V334-A338 HydrophobicContact CG2-CB 3.8Å; V334-V339 HydrophobicContact CG1-CG2 3.91Å; V334-V339 HydrophobicContact CG2-CG2 3.88Å
335	T	91.1	Very high	90.2	Very high	84 Å²	84	57.6 Å²	57.6	52%	0.515	31%	0.313	S	S	.	.			trans	-82.4	151.4	175.6	66	0	0	0	0	110.8	S337 A338 V339	T335-S337 PolarHBondContact O-N 2.89Å; T335-A338 WeakPolarHBondContact O-CB 3.47Å; T335-A338 PolarHBondContact O-N 3.49Å; T335-A338 WeakPolarHBondContact OG1-CB 3.46Å; T335-A338 PolarHBondContact OG1-N 3.22Å; T335-V339 PolarHBondContact O-N 3.39Å; T335-V339 VanDerWaalsContact O-N 3.12Å
336	R	88	Confident	88.7	Confident	158 Å²	158	60.9 Å²	60.9	60%	0.596	34%	0.336	S	S	*	.	H	α-helix	trans	-53.2	-40.9	173	-63.2	-177.4	-171.4	145.3	1.1	111.7	I247 F324 A338 V339 V340	I247-R336 HydrophobicContact CG2-CG 4.18Å; F324-R336 HydrophobicContact CE1-CB 4.31Å; F324-R336 HydrophobicContact CE1-CG 4.3Å; R336-A338 VanDerWaalsContact C-N 3.31Å; R336-A338 PolarHBondContact O-N 3.17Å; R336-V339 PolarHBondContact O-N 2.9Å; R336-V340 WeakPolarHBondContact O-CG2 3.49Å; R336-V340 PolarHBondContact O-N 3.48Å
337	S	87.8	Confident	87.4	Confident	67 Å²	67	61.4 Å²	61.4	47%	0.469	34%	0.343	S	S	.	.	H	α-helix	trans	-60.7	-38	177.2	-56.2	0	0	0	0	112.8	T335 K341	T335-S337 PolarHBondContact O-N 2.89Å; S337-K341 WeakPolarHBondContact O-CB 3.22Å; S337-K341 PolarHBondContact O-N 3.48Å
338	A	89.3	Confident	85.8	Confident	44 Å²	44	62.4 Å²	62.4	36%	0.364	35%	0.351	S	S	.	.	H	α-helix	trans	-68.8	-39.8	175.9	0	0	0	0	0	111.9	V334 T335 R336 K341 L342	V334-A338 HydrophobicContact CG2-CB 3.8Å; T335-A338 WeakPolarHBondContact O-CB 3.47Å; T335-A338 PolarHBondContact O-N 3.49Å; T335-A338 WeakPolarHBondContact OG1-CB 3.46Å; T335-A338 PolarHBondContact OG1-N 3.22Å; R336-A338 VanDerWaalsContact C-N 3.31Å; R336-A338 PolarHBondContact O-N 3.17Å; A338-K341 WeakPolarHBondContact O-CB 3.3Å; A338-K341 PolarHBondContact O-N 3.4Å; A338-L342 PolarHBondContact O-N 3.41Å; A338-L342 VanDerWaalsContact O-N 3.16Å
339	V	91.3	Very high	84.2	Confident	1 Å²	1	62.6 Å²	62.6	1%	0.006	36%	0.358	C	S	.	.	H	α-helix	trans	-63.1	-46.2	174.4	-175.9	0	0	0	0	111.1	V323 F324 I327 V334 T335 R336 K341 L342 I343	V323-V339 HydrophobicContact CG1-CG1 3.74Å; F324-V339 HydrophobicContact CB-CG1 4.45Å; F324-V339 HydrophobicContact CD1-CB 4.4Å; F324-V339 HydrophobicContact CD1-CG1 4Å; F324-V339 HydrophobicContact CD2-CG1 3.63Å; F324-V339 HydrophobicContact CE1-CB 4.21Å; F324-V339 HydrophobicContact CE1-CG1 4.14Å; F324-V339 HydrophobicContact CE2-CB 4.48Å; F324-V339 HydrophobicContact CE2-CG1 3.8Å; F324-V339 HydrophobicContact CG-CG1 3.77Å; F324-V339 HydrophobicContact CZ-CB 4.28Å; F324-V339 HydrophobicContact CZ-CG1 4.07Å; I327-V339 HydrophobicContact CB-CG2 4.35Å; I327-V339 HydrophobicContact CG2-CG2 3.93Å; V334-V339 HydrophobicContact CG1-CG2 3.91Å; V334-V339 HydrophobicContact CG2-CG2 3.88Å; T335-V339 PolarHBondContact O-N 3.39Å; T335-V339 VanDerWaalsContact O-N 3.12Å; R336-V339 PolarHBondContact O-N 2.9Å; V339-K341 VanDerWaalsContact C-N 3.29Å; V339-K341 PolarHBondContact O-N 3.12Å; V339-L342 WeakPolarHBondContact O-CB 3.38Å; V339-L342 PolarHBondContact O-N 3.34Å; V339-L342 VanDerWaalsContact O-N 3.16Å; V339-I343 PolarHBondContact O-N 3.26Å
340	V	89.6	Confident	83	Confident	5 Å²	5	60.3 Å²	60.3	3%	0.03	35%	0.353	C	S	.	.	H	α-helix	trans	-64	-36.7	176.7	175.3	0	0	0	0	111.1	F251 F324 R336 L342 I343 K344	F251-V340 HydrophobicContact CD1-CG2 4.31Å; F251-V340 HydrophobicContact CD2-CG2 4.09Å; F251-V340 HydrophobicContact CE1-CG1 4.48Å; F251-V340 HydrophobicContact CE1-CG2 3.91Å; F251-V340 HydrophobicContact CE2-CG2 3.66Å; F251-V340 HydrophobicContact CG-CG2 4.4Å; F251-V340 HydrophobicContact CZ-CB 4.44Å; F251-V340 HydrophobicContact CZ-CG1 4.01Å; F251-V340 HydrophobicContact CZ-CG2 3.56Å; F324-V340 HydrophobicContact CE2-CG2 4.25Å; F324-V340 HydrophobicContact CZ-CG2 3.77Å; R336-V340 WeakPolarHBondContact O-CG2 3.49Å; R336-V340 PolarHBondContact O-N 3.48Å; V340-L342 VanDerWaalsContact C-N 3.25Å; V340-L342 PolarHBondContact O-N 2.85Å; V340-I343 PolarHBondContact O-N 3.41Å; V340-I343 VanDerWaalsContact O-N 3.13Å; V340-K344 HydrophobicContact CG1-CD 4.07Å; V340-K344 HydrophobicContact CG1-CG 4.26Å; V340-K344 VanDerWaalsContact O-CG 3.32Å; V340-K344 WeakPolarHBondContact O-CG 3.17Å; V340-K344 PolarHBondContact O-N 3.35Å
341	K	88.3	Confident	82.3	Confident	152 Å²	152	56.3 Å²	56.3	66%	0.661	33%	0.328	S	S	*	.	H	α-helix	trans	-58.7	-37.9	175.1	-172.3	179.6	179	-175.4	0	111.7	S337 A338 V339 K344 T345	S337-K341 WeakPolarHBondContact O-CB 3.22Å; S337-K341 PolarHBondContact O-N 3.48Å; A338-K341 WeakPolarHBondContact O-CB 3.3Å; A338-K341 PolarHBondContact O-N 3.4Å; V339-K341 VanDerWaalsContact C-N 3.29Å; V339-K341 PolarHBondContact O-N 3.12Å; K341-K344 CarbonylContact O-C 3.5Å; K341-K344 WeakPolarHBondContact O-CB 3.36Å; K341-K344 PolarHBondContact O-N 2.81Å; K341-T345 PolarHBondContact O-N 3.12Å; K341-T345 PolarHBondContact O-OG1 2.96Å; K341-T345 VanDerWaalsContact O-OG1 3.14Å
342	L	87.7	Confident	81.8	Confident	18 Å²	18	52.9 Å²	52.9	9%	0.094	31%	0.31	C	S	.	.	H	α-helix	trans	-62.8	-44.2	174	-177.5	159.9	0	0	0	111.9	V323 I327 A338 V339 V340 K344 T345 W357	V323-L342 HydrophobicContact CG1-CD2 3.95Å; I327-L342 HydrophobicContact CD1-CD1 3.67Å; I327-L342 HydrophobicContact CG1-CD1 4.06Å; A338-L342 PolarHBondContact O-N 3.41Å; A338-L342 VanDerWaalsContact O-N 3.16Å; V339-L342 WeakPolarHBondContact O-CB 3.38Å; V339-L342 PolarHBondContact O-N 3.34Å; V339-L342 VanDerWaalsContact O-N 3.16Å; V340-L342 VanDerWaalsContact C-N 3.25Å; V340-L342 PolarHBondContact O-N 2.85Å; L342-K344 PolarHBondContact O-N 3.06Å; L342-T345 VanDerWaalsContact O-CB 3.27Å; L342-T345 WeakPolarHBondContact O-CB 3.03Å; L342-T345 PolarHBondContact O-N 3.02Å; L342-T345 PolarHBondContact O-OG1 3.23Å; L342-W357 HydrophobicContact CD1-CD2 3.86Å; L342-W357 HydrophobicContact CD1-CE3 3.78Å; L342-W357 HydrophobicContact CD1-CH2 3.52Å; L342-W357 HydrophobicContact CD1-CZ2 3.59Å; L342-W357 HydrophobicContact CD1-CZ3 3.64Å; L342-W357 HydrophobicContact CD2-CB 4.22Å; L342-W357 HydrophobicContact CD2-CD2 3.81Å; L342-W357 HydrophobicContact CD2-CE3 4.24Å; L342-W357 HydrophobicContact CD2-CG 3.82Å; L342-W357 HydrophobicContact CG-CD2 3.82Å; L342-W357 HydrophobicContact CG-CE3 4.25Å; L342-W357 HydrophobicContact CG-CG 4.21Å; L342-W357 HydrophobicContact CG-CH2 4.29Å; L342-W357 HydrophobicContact CG-CZ2 3.86Å; L342-W357 HydrophobicContact CG-CZ3 4.49Å
343	I	88.2	Confident	81.6	Confident	0 Å²	0	47.8 Å²	47.8	0%	0	28%	0.276	C	S	.	.	H	α-helix	trans	-64.4	-33.4	176.3	-51.4	174.7	0	0	0	110.8	A84 F320 V323 F324 V339 V340 T345 L353	A84-I343 HydrophobicContact CB-CB 3.91Å; A84-I343 HydrophobicContact CB-CG2 3.41Å; A84-I343 VanDerWaalsContact CB-CG2 3.41Å; F320-I343 HydrophobicContact CD1-CD1 3.76Å; F320-I343 HydrophobicContact CD2-CD1 4.24Å; F320-I343 HydrophobicContact CE1-CD1 3.76Å; F320-I343 HydrophobicContact CE2-CD1 4.28Å; F320-I343 HydrophobicContact CE2-CG2 4.17Å; F320-I343 HydrophobicContact CG-CD1 4.01Å; F320-I343 HydrophobicContact CZ-CD1 4.06Å; F320-I343 HydrophobicContact CZ-CG2 4.24Å; V323-I343 HydrophobicContact CB-CD1 4.18Å; V323-I343 HydrophobicContact CB-CG1 4.24Å; V323-I343 HydrophobicContact CG1-CD1 4.05Å; V323-I343 HydrophobicContact CG1-CG1 3.77Å; V323-I343 HydrophobicContact CG2-CD1 4.43Å; V323-I343 HydrophobicContact CG2-CG1 4.2Å; F324-I343 HydrophobicContact CD2-CD1 4.43Å; F324-I343 HydrophobicContact CE2-CD1 4.07Å; V339-I343 PolarHBondContact O-N 3.26Å; V340-I343 PolarHBondContact O-N 3.41Å; V340-I343 VanDerWaalsContact O-N 3.13Å; I343-T345 VanDerWaalsContact C-N 3.3Å; I343-L353 HydrophobicContact CG2-CD1 4.35Å; I343-L353 HydrophobicContact CG2-CD2 3.66Å
344	K	86	Confident	81.6	Confident	69 Å²	69	42 Å²	42	30%	0.3	24%	0.241	S	C	.	.	T	Hydrogen-bonded Turn	trans	-75.3	-12.2	173.9	-69.8	178.2	171.1	-174	0	113.8	A84 S87 V340 K341 L342 S346	A84-K344 HydrophobicContact CB-CG 4.11Å; A84-K344 WeakPolarHBondContact O-CE 3.16Å; S87-K344 PolarHBondContact O-NZ 3.31Å; V340-K344 HydrophobicContact CG1-CD 4.07Å; V340-K344 HydrophobicContact CG1-CG 4.26Å; V340-K344 VanDerWaalsContact O-CG 3.32Å; V340-K344 WeakPolarHBondContact O-CG 3.17Å; V340-K344 PolarHBondContact O-N 3.35Å; K341-K344 CarbonylContact O-C 3.5Å; K341-K344 WeakPolarHBondContact O-CB 3.36Å; K341-K344 PolarHBondContact O-N 2.81Å; L342-K344 PolarHBondContact O-N 3.06Å; K344-S346 PolarHBondContact O-N 3Å
345	T	79.4	Confident	81.6	Confident	47 Å²	47	40.5 Å²	40.5	29%	0.288	23%	0.232	S	C	.	.			trans	-61.9	104.9	-178.5	-62	0	0	0	0	109.2	K341 L342 I343 G347	K341-T345 PolarHBondContact O-N 3.12Å; K341-T345 PolarHBondContact O-OG1 2.96Å; K341-T345 VanDerWaalsContact O-OG1 3.14Å; L342-T345 VanDerWaalsContact O-CB 3.27Å; L342-T345 WeakPolarHBondContact O-CB 3.03Å; L342-T345 PolarHBondContact O-N 3.02Å; L342-T345 PolarHBondContact O-OG1 3.23Å; I343-T345 VanDerWaalsContact C-N 3.3Å; T345-G347 PolarHBondContact O-N 2.64Å
346	S	64.8	Low	81.5	Confident	69 Å²	69	36.8 Å²	36.8	48%	0.483	21%	0.209	S	C	.	.			trans	-80.3	106.3	169.9	-63.9	0	0	0	0	107.8	K344	K344-S346 PolarHBondContact O-N 3Å
347	G	67.5	Low	81.7	Confident	16 Å²	16	30.7 Å²	30.7	17%	0.165	19%	0.186	C	C	.	.			trans	-69.3	178.9	159.1	0	0	0	0	0	111	T345 G349 S350	T345-G347 PolarHBondContact O-N 2.64Å; G347-G349 PolarHBondContact O-N 2.69Å; G347-S350 PolarHBondContact O-N 3.17Å
348	P	60.7	Low	82	Confident	44 Å²	44	27.5 Å²	27.5	29%	0.286	16%	0.164	S	C	.	.	G	3₁₀ helix	trans	-47.9	133.4	175.6	-24.4	33.3	0	0	0	111.1	F185 S350 T351 L428	F185-P348 HydrophobicContact CE1-CB 4.09Å; F185-P348 HydrophobicContact CE1-CG 4.18Å; P348-S350 PolarHBondContact O-N 3.18Å; P348-T351 WeakPolarHBondContact O-CB 3.27Å; P348-T351 WeakPolarHBondContact O-CG2 3.28Å; P348-T351 PolarHBondContact O-N 3.34Å; P348-T351 PolarHBondContact O-OG1 2.94Å; P348-L428 HydrophobicContact CB-CD2 3.13Å
349	G	60.4	Low	82.3	Confident	25 Å²	25	25.6 Å²	25.6	26%	0.258	15%	0.148	S	C	.	.	G	3₁₀ helix	trans	63.8	22	-179.8	0	0	0	0	0	115.3	G347 T351	G347-G349 PolarHBondContact O-N 2.69Å; G349-T351 VanDerWaalsContact C-N 3.35Å; G349-T351 PolarHBondContact O-N 3.15Å
350	S	67	Low	82.5	Confident	45 Å²	45	25.8 Å²	25.8	32%	0.315	15%	0.149	S	C	.	.	G	3₁₀ helix	trans	64.3	30.7	-177.7	-59.4	0	0	0	0	115.2	R81 G347 P348	R81-S350 WeakPolarHBondContact CD-O 3.47Å; R81-S350 PolarHBondContact NE-O 3.26Å; G347-S350 PolarHBondContact O-N 3.17Å; P348-S350 PolarHBondContact O-N 3.18Å
351	T	75.1	Confident	82.7	Confident	1 Å²	1	25.6 Å²	25.6	1%	0.006	15%	0.148	C	C	.	.			trans	-101.6	-14.8	-171.6	60.5	0	0	0	0	115.9	W77 W161 P348 G349 L353 T354 F355	W77-T351 HydrophobicContact CH2-CG2 4.32Å; W77-T351 HydrophobicContact CZ3-CG2 4.07Å; W161-T351 HydrophobicContact CE3-CG2 4.04Å; W161-T351 HydrophobicContact CH2-CG2 3.96Å; W161-T351 HydrophobicContact CZ3-CG2 3.26Å; P348-T351 WeakPolarHBondContact O-CB 3.27Å; P348-T351 WeakPolarHBondContact O-CG2 3.28Å; P348-T351 PolarHBondContact O-N 3.34Å; P348-T351 PolarHBondContact O-OG1 2.94Å; G349-T351 VanDerWaalsContact C-N 3.35Å; G349-T351 PolarHBondContact O-N 3.15Å; T351-L353 PolarHBondContact O-N 2.89Å; T351-L353 VanDerWaalsContact O-N 3.16Å; T351-T354 PolarHBondContact O-N 3.2Å; T351-F355 HydrophobicContact CG2-CD2 4.2Å; T351-F355 HydrophobicContact CG2-CE2 4.46Å; T351-F355 PolarHBondContact O-N 2.98Å; T351-F355 VanDerWaalsContact O-N 3.11Å
352	G	80.7	Confident	83.1	Confident	1 Å²	1	18.5 Å²	18.5	1%	0.01	12%	0.117	C	C	.	.	H	α-helix	trans	-50.5	-46.4	-165.8	0	0	0	0	0	115	T354 T356 W357	G352-T354 VanDerWaalsContact C-N 3.34Å; G352-T354 PolarHBondContact O-N 2.72Å; G352-T356 WeakPolarHBondContact O-CA 3.43Å; G352-T356 WeakPolarHBondContact O-CB 3.38Å; G352-T356 PolarHBondContact O-N 3.27Å; G352-W357 PolarHBondContact O-N 2.81Å; G352-W357 VanDerWaalsContact O-N 3.1Å
353	L	87.5	Confident	83.5	Confident	2 Å²	2	18.9 Å²	18.9	1%	0.01	12%	0.121	C	C	.	.	I	π-helix	trans	-53.5	-51.1	178.8	176.4	58.5	0	0	0	112.3	R81 I319 V323 I343 T351 W357 I358	R81-L353 HydrophobicContact CB-CD2 4.17Å; I319-L353 HydrophobicContact CG2-CD1 4.43Å; I319-L353 HydrophobicContact CG2-CD2 4.06Å; V323-L353 HydrophobicContact CG2-CD1 4.46Å; I343-L353 HydrophobicContact CG2-CD1 4.35Å; I343-L353 HydrophobicContact CG2-CD2 3.66Å; T351-L353 PolarHBondContact O-N 2.89Å; T351-L353 VanDerWaalsContact O-N 3.16Å; L353-W357 HydrophobicContact CD1-CB 4.44Å; L353-W357 WeakPolarHBondContact O-CB 3.43Å; L353-W357 PolarHBondContact O-N 3.11Å; L353-I358 WeakPolarHBondContact O-CG1 3.3Å; L353-I358 PolarHBondContact O-N 3.37Å
354	T	92	Very high	83.8	Confident	3 Å²	3	23.7 Å²	23.7	2%	0.018	14%	0.142	C	C	.	.	I	π-helix	trans	-80	-44.7	-169.6	-58.7	0	0	0	0	112.1	W77 T351 G352 I358 F376 F377 L380	W77-T354 HydrophobicContact CB-CG2 3.71Å; W77-T354 WeakPolarHBondContact CB-OG1 3.17Å; T351-T354 PolarHBondContact O-N 3.2Å; G352-T354 VanDerWaalsContact C-N 3.34Å; G352-T354 PolarHBondContact O-N 2.72Å; T354-I358 WeakPolarHBondContact O-CB 3.31Å; T354-F376 HydrophobicContact CG2-CE1 3.84Å; T354-F376 HydrophobicContact CG2-CZ 4.27Å; T354-F377 HydrophobicContact CG2-CE1 4.22Å; T354-L380 HydrophobicContact CG2-CD1 4Å
355	F	91.8	Very high	84.2	Confident	0 Å²	0	22.6 Å²	22.6	0%	0	14%	0.137	C	C	.	.	I	π-helix	trans	-98.6	-15.3	-170.5	-62	-79.6	0	0	0	113.1	W77 W161 Y165 F185 T351 F377	W77-F355 HydrophobicContact CE3-CE2 4.11Å; W77-F355 HydrophobicContact CZ3-CE2 4.26Å; W161-F355 HydrophobicContact CB-CD1 4.3Å; W161-F355 HydrophobicContact CB-CE1 3.6Å; W161-F355 HydrophobicContact CB-CZ 3.83Å; W161-F355 HydrophobicContact CE3-CD2 4.42Å; W161-F355 AromaticContact CE3-CE2 3.92Å; W161-F355 HydrophobicContact CE3-CE2 3.92Å; W161-F355 HydrophobicContact CE3-CZ 4.06Å; Y165-F355 HydrophobicContact CD1-CD1 4.29Å; Y165-F355 AromaticContact CD2-CD1 3.53Å; Y165-F355 HydrophobicContact CD2-CD1 3.53Å; Y165-F355 HydrophobicContact CD2-CE1 4.1Å; Y165-F355 HydrophobicContact CE1-CB 4.21Å; Y165-F355 HydrophobicContact CE1-CD1 4.33Å; Y165-F355 WeakPolarHBondContact CE1-O 3.36Å; Y165-F355 HydrophobicContact CE2-CB 4.11Å; Y165-F355 AromaticContact CE2-CD1 3.58Å; Y165-F355 HydrophobicContact CE2-CD1 3.58Å; Y165-F355 HydrophobicContact CE2-CE1 4.48Å; Y165-F355 HydrophobicContact CE2-CG 4.28Å; Y165-F355 AromaticContact CG-CD1 3.89Å; Y165-F355 HydrophobicContact CG-CD1 3.89Å; Y165-F355 HydrophobicContact CG-CE1 4.45Å; Y165-F355 AromaticContact CZ-CD1 3.98Å; Y165-F355 PolarHBondContact OH-O 3.34Å; F185-F355 HydrophobicContact CD2-CB 3.82Å; F185-F355 HydrophobicContact CE2-CB 4.24Å; T351-F355 HydrophobicContact CG2-CD2 4.2Å; T351-F355 HydrophobicContact CG2-CE2 4.46Å; T351-F355 PolarHBondContact O-N 2.98Å; T351-F355 VanDerWaalsContact O-N 3.11Å; F355-F377 AromaticContact CD1-CE1 3.88Å; F355-F377 HydrophobicContact CD1-CE1 3.88Å; F355-F377 HydrophobicContact CD1-CZ 4.37Å; F355-F377 AromaticContact CE1-CE1 3.79Å; F355-F377 HydrophobicContact CE1-CE1 3.79Å
356	T	89.6	Confident	84.8	Confident	5 Å²	5	22.7 Å²	22.7	3%	0.031	15%	0.147	C	C	.	.	I	π-helix	trans	-103.1	-53	172.7	-52.1	0	0	0	0	110.8	E178 L182 G352 V360	E178-T356 HydrophobicContact CG-CG2 4.26Å; L182-T356 HydrophobicContact CB-CG2 4.17Å; G352-T356 WeakPolarHBondContact O-CA 3.43Å; G352-T356 WeakPolarHBondContact O-CB 3.38Å; G352-T356 PolarHBondContact O-N 3.27Å; T356-V360 VanDerWaalsContact O-CG2 3.27Å; T356-V360 WeakPolarHBondContact O-CG2 3.36Å
357	W	92	Very high	86.2	Confident	31 Å²	31	25.6 Å²	25.6	12%	0.117	16%	0.157	C	C	.	.	I	π-helix	trans	-88.5	-36.7	-167.5	-80.6	103.3	0	0	0	115.2	E178 I327 L342 G352 L353 V360 L361	E178-W357 HydrophobicContact CB-CH2 3.76Å; E178-W357 HydrophobicContact CB-CZ2 3.62Å; E178-W357 HydrophobicContact CB-CZ3 4.41Å; E178-W357 HydrophobicContact CG-CH2 4.28Å; E178-W357 HydrophobicContact CG-CZ2 3.61Å; E178-W357 WeakPolarHBondContact OE1-CZ2 3.49Å; E178-W357 PolarHBondContact OE1-NE1 2.76Å; E178-W357 VanDerWaalsContact OE2-CZ2 3.29Å; E178-W357 WeakPolarHBondContact OE2-CZ2 3.33Å; I327-W357 HydrophobicContact CD1-CZ3 4.48Å; L342-W357 HydrophobicContact CD1-CD2 3.86Å; L342-W357 HydrophobicContact CD1-CE3 3.78Å; L342-W357 HydrophobicContact CD1-CH2 3.52Å; L342-W357 HydrophobicContact CD1-CZ2 3.59Å; L342-W357 HydrophobicContact CD1-CZ3 3.64Å; L342-W357 HydrophobicContact CD2-CB 4.22Å; L342-W357 HydrophobicContact CD2-CD2 3.81Å; L342-W357 HydrophobicContact CD2-CE3 4.24Å; L342-W357 HydrophobicContact CD2-CG 3.82Å; L342-W357 HydrophobicContact CG-CD2 3.82Å; L342-W357 HydrophobicContact CG-CE3 4.25Å; L342-W357 HydrophobicContact CG-CG 4.21Å; L342-W357 HydrophobicContact CG-CH2 4.29Å; L342-W357 HydrophobicContact CG-CZ2 3.86Å; L342-W357 HydrophobicContact CG-CZ3 4.49Å; G352-W357 PolarHBondContact O-N 2.81Å; G352-W357 VanDerWaalsContact O-N 3.1Å; L353-W357 HydrophobicContact CD1-CB 4.44Å; L353-W357 WeakPolarHBondContact O-CB 3.43Å; L353-W357 PolarHBondContact O-N 3.11Å; W357-V360 HydrophobicContact CE3-CB 4.29Å; W357-V360 HydrophobicContact CE3-CG1 4.08Å; W357-V360 HydrophobicContact CZ3-CG1 4.08Å; W357-V360 WeakPolarHBondContact O-CB 3.42Å; W357-V360 PolarHBondContact O-N 3.34Å; W357-V360 VanDerWaalsContact O-N 3.1Å; W357-L361 HydrophobicContact CB-CD1 4.34Å; W357-L361 WeakPolarHBondContact O-CB 3.49Å; W357-L361 VanDerWaalsContact O-CG 3.24Å; W357-L361 WeakPolarHBondContact O-CG 3.22Å; W357-L361 PolarHBondContact O-N 3.17Å
358	I	94.1	Very high	87.6	Confident	0 Å²	0	29 Å²	29	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-58.3	-46.8	-178.8	-66.3	-59.5	0	0	0	113.1	I319 L353 T354 V360 L361 F362 F376	I319-I358 HydrophobicContact CD1-CD1 3.45Å; I319-I358 VanDerWaalsContact CD1-CD1 3.45Å; I319-I358 HydrophobicContact CD1-CG1 4.3Å; L353-I358 WeakPolarHBondContact O-CG1 3.3Å; L353-I358 PolarHBondContact O-N 3.37Å; T354-I358 WeakPolarHBondContact O-CB 3.31Å; I358-V360 VanDerWaalsContact C-N 3.28Å; I358-V360 PolarHBondContact O-N 3.36Å; I358-L361 HydrophobicContact CD1-CD1 4.21Å; I358-L361 PolarHBondContact O-N 3.45Å; I358-F362 HydrophobicContact CG2-CD2 3.45Å; I358-F362 VanDerWaalsContact CG2-CD2 3.45Å; I358-F362 HydrophobicContact CG2-CE2 3.29Å; I358-F362 HydrophobicContact CG2-CZ 4.35Å; I358-F362 WeakPolarHBondContact O-CD2 3.04Å; I358-F362 PolarHBondContact O-N 2.93Å; I358-F376 HydrophobicContact CB-CE1 4.41Å; I358-F376 HydrophobicContact CG1-CE1 4.23Å; I358-F376 HydrophobicContact CG1-CZ 4.37Å; I358-F376 HydrophobicContact CG2-CD1 3.76Å; I358-F376 HydrophobicContact CG2-CE1 3.9Å; I358-F376 HydrophobicContact CG2-CG 4.27Å
359	P	95.4	Very high	89.3	Confident	4 Å²	4	26.9 Å²	26.9	3%	0.026	15%	0.154	C	C	.	.	H	α-helix	trans	-58.5	-40	174	-24.7	34.5	0	0	0	112.9	Y165 L174 P175 F362 S363 F377	Y165-P359 HydrophobicContact CD1-CG 3.96Å; Y165-P359 HydrophobicContact CE1-CG 3.92Å; L174-P359 HydrophobicContact CD2-CB 4.46Å; P175-P359 HydrophobicContact CG-CB 3.69Å; P359-F362 PolarHBondContact O-N 2.67Å; P359-S363 PolarHBondContact O-N 2.95Å; P359-F377 HydrophobicContact CG-CE2 4.12Å; P359-F377 HydrophobicContact CG-CZ 4.33Å
360	V	94.5	Very high	91	Very high	4 Å²	4	29.5 Å²	29.5	2%	0.024	16%	0.156	C	C	.	.	H	α-helix	trans	-65.1	-43.9	178.8	174.4	0	0	0	0	111.7	P175 T177 T356 W357 I358 S363	P175-V360 HydrophobicContact CB-CG2 4.12Å; P175-V360 HydrophobicContact CG-CG2 3.96Å; P175-V360 WeakPolarHBondContact O-CA 3.33Å; T177-V360 WeakPolarHBondContact O-CG2 3.41Å; T356-V360 VanDerWaalsContact O-CG2 3.27Å; T356-V360 WeakPolarHBondContact O-CG2 3.36Å; W357-V360 HydrophobicContact CE3-CB 4.29Å; W357-V360 HydrophobicContact CE3-CG1 4.08Å; W357-V360 HydrophobicContact CZ3-CG1 4.08Å; W357-V360 WeakPolarHBondContact O-CB 3.42Å; W357-V360 PolarHBondContact O-N 3.34Å; W357-V360 VanDerWaalsContact O-N 3.1Å; I358-V360 VanDerWaalsContact C-N 3.28Å; I358-V360 PolarHBondContact O-N 3.36Å; V360-S363 WeakPolarHBondContact O-CB 3.49Å; V360-S363 PolarHBondContact O-N 2.87Å; V360-S363 PolarHBondContact O-OG 3.48Å
361	L	94.5	Very high	92.5	Very high	2 Å²	2	31.4 Å²	31.4	1%	0.01	16%	0.161	C	C	.	.	H	α-helix	trans	-65	-45.2	178.3	-68.4	163	0	0	0	110.7	V323 T326 I327 W357 I358 S363 K364	V323-L361 HydrophobicContact CB-CD1 4.39Å; V323-L361 HydrophobicContact CG2-CD1 3.55Å; T326-L361 HydrophobicContact CG2-CD2 3.83Å; I327-L361 HydrophobicContact CD1-CD2 3.97Å; I327-L361 HydrophobicContact CG1-CD2 4.09Å; W357-L361 HydrophobicContact CB-CD1 4.34Å; W357-L361 WeakPolarHBondContact O-CB 3.49Å; W357-L361 VanDerWaalsContact O-CG 3.24Å; W357-L361 WeakPolarHBondContact O-CG 3.22Å; W357-L361 PolarHBondContact O-N 3.17Å; I358-L361 HydrophobicContact CD1-CD1 4.21Å; I358-L361 PolarHBondContact O-N 3.45Å; L361-S363 VanDerWaalsContact C-N 3.31Å; L361-S363 PolarHBondContact O-N 3.39Å; L361-K364 WeakPolarHBondContact O-CB 3.28Å; L361-K364 PolarHBondContact O-N 2.64Å
362	F	96.6	Very high	93.6	Very high	2 Å²	2	31.3 Å²	31.3	1%	0.009	16%	0.161	C	C	.	.	H	α-helix	trans	-68.4	-28.1	177.8	-75.1	-42.8	0	0	0	113.4	L174 M235 W238 T322 I358 P359 K364 F365 G369 L372 C373 F376	L174-F362 HydrophobicContact CD1-CB 4.1Å; M235-F362 HydrophobicContact CE-CE1 4.4Å; M235-F362 HydrophobicContact CE-CE2 4.06Å; M235-F362 HydrophobicContact CE-CZ 3.47Å; M235-F362 VanDerWaalsContact CE-CZ 3.47Å; W238-F362 HydrophobicContact CH2-CD1 4.25Å; W238-F362 AromaticContact CH2-CE1 3.87Å; W238-F362 HydrophobicContact CH2-CE1 3.87Å; W238-F362 AromaticContact CZ3-CE1 3.72Å; W238-F362 HydrophobicContact CZ3-CE1 3.72Å; T322-F362 HydrophobicContact CG2-CE1 4Å; I358-F362 HydrophobicContact CG2-CD2 3.45Å; I358-F362 VanDerWaalsContact CG2-CD2 3.45Å; I358-F362 HydrophobicContact CG2-CE2 3.29Å; I358-F362 HydrophobicContact CG2-CZ 4.35Å; I358-F362 WeakPolarHBondContact O-CD2 3.04Å; I358-F362 PolarHBondContact O-N 2.93Å; P359-F362 PolarHBondContact O-N 2.67Å; F362-K364 PolarHBondContact O-N 3.16Å; F362-F365 PolarHBondContact O-N 3.39Å; F362-G369 WeakPolarHBondContact CB-O 3.27Å; F362-G369 WeakPolarHBondContact O-CA 3.27Å; F362-L372 HydrophobicContact CD1-CB 3.79Å; F362-L372 HydrophobicContact CD1-CD1 4.03Å; F362-L372 HydrophobicContact CE1-CB 3.8Å; F362-L372 HydrophobicContact CE1-CD1 4.04Å; F362-L372 HydrophobicContact CG-CB 4.24Å; F362-L372 HydrophobicContact CZ-CB 4.2Å; F362-C373 HydrophobicContact CB-CB 3.97Å; F362-C373 HydrophobicContact CD2-CB 3.71Å; F362-C373 HydrophobicContact CG-CB 4.17Å; F362-F376 HydrophobicContact CE2-CB 4.04Å; F362-F376 HydrophobicContact CE2-CG 4.31Å
363	S	96.1	Very high	94.4	Very high	26 Å²	26	31.3 Å²	31.3	18%	0.182	16%	0.161	C	C	.	.	H	α-helix	trans	-55.6	-24.9	175.5	81.1	0	0	0	0	113.7	P175 P359 V360 L361 F365 G366	P175-S363 WeakPolarHBondContact O-CB 3.34Å; P175-S363 PolarHBondContact O-OG 3.31Å; P359-S363 PolarHBondContact O-N 2.95Å; V360-S363 WeakPolarHBondContact O-CB 3.49Å; V360-S363 PolarHBondContact O-N 2.87Å; V360-S363 PolarHBondContact O-OG 3.48Å; L361-S363 VanDerWaalsContact C-N 3.31Å; L361-S363 PolarHBondContact O-N 3.39Å; S363-F365 PolarHBondContact O-N 2.85Å; S363-G366 PolarHBondContact O-N 2.85Å
364	K	94.3	Very high	94.9	Very high	102 Å²	102	31.8 Å²	31.8	44%	0.443	17%	0.165	S	C	.	.	T	Hydrogen-bonded Turn	trans	-72.1	-11.4	-179.2	-53	-53.4	176.5	-170.9	0	113.8	K176 T326 L361 F362	K176-K364 PolarHBondContact O-NZ 2.87Å; T326-K364 HydrophobicContact CG2-CB 3.91Å; T326-K364 HydrophobicContact CG2-CG 3.54Å; L361-K364 WeakPolarHBondContact O-CB 3.28Å; L361-K364 PolarHBondContact O-N 2.64Å; F362-K364 PolarHBondContact O-N 3.16Å
365	F	93.7	Very high	95.2	Very high	45 Å²	45	33.7 Å²	33.7	20%	0.197	18%	0.175	C	C	.	.	T	Hydrogen-bonded Turn	trans	-106	19.8	180	-56.1	-83.9	0	0	0	113.2	W238 F362 S363 F368 G369	W238-F365 HydrophobicContact CH2-CD2 4.19Å; W238-F365 HydrophobicContact CH2-CE1 4.47Å; W238-F365 AromaticContact CH2-CE2 3.87Å; W238-F365 HydrophobicContact CH2-CE2 3.87Å; W238-F365 HydrophobicContact CH2-CZ 4.01Å; W238-F365 HydrophobicContact CZ2-CD1 4.08Å; W238-F365 HydrophobicContact CZ2-CD2 4.19Å; W238-F365 AromaticContact CZ2-CE1 4Å; W238-F365 HydrophobicContact CZ2-CE1 4Å; W238-F365 HydrophobicContact CZ2-CE2 4.11Å; W238-F365 HydrophobicContact CZ2-CG 4.17Å; W238-F365 HydrophobicContact CZ2-CZ 4.01Å; F362-F365 PolarHBondContact O-N 3.39Å; S363-F365 PolarHBondContact O-N 2.85Å; F365-F368 PolarHBondContact O-N 3.23Å; F365-G369 PolarHBondContact O-N 3Å
366	G	93	Very high	95.5	Very high	49 Å²	49	34 Å²	34	51%	0.505	18%	0.176	S	C	.	.	H	α-helix	trans	58.2	-136.9	175.9	0	0	0	0	0	113.1	S363 F368 G369 R370	S363-G366 PolarHBondContact O-N 2.85Å; G366-F368 VanDerWaalsContact C-N 3.33Å; G366-F368 PolarHBondContact O-N 2.91Å; G366-G369 PolarHBondContact O-N 3.13Å; G366-R370 PolarHBondContact O-N 3.45Å
367	L	94.6	Very high	95.9	Very high	130 Å²	130	33.8 Å²	33.8	68%	0.681	18%	0.175	S	C	*	.	H	α-helix	trans	-61.2	-40.1	-179.5	-179.6	61.6	0	0	0	112.5	G369 R370 I371	L367-G369 VanDerWaalsContact C-N 3.31Å; L367-G369 PolarHBondContact O-N 3.19Å; L367-R370 WeakPolarHBondContact O-CB 3.46Å; L367-R370 PolarHBondContact O-N 2.92Å; L367-I371 PolarHBondContact O-N 2.96Å
368	F	95.7	Very high	96.2	Very high	87 Å²	87	34.3 Å²	34.3	38%	0.382	18%	0.18	S	C	.	.	H	α-helix	trans	-65.7	-38	178.4	-171.2	-105.7	0	0	0	111.5	F234 W238 F365 G366 R370 I371 L372	F234-F368 HydrophobicContact CZ-CZ 4.13Å; W238-F368 AromaticContact CD1-CE1 3.6Å; W238-F368 HydrophobicContact CG-CE1 4.31Å; W238-F368 AromaticContact NE1-CE1 3.4Å; F365-F368 PolarHBondContact O-N 3.23Å; G366-F368 VanDerWaalsContact C-N 3.33Å; G366-F368 PolarHBondContact O-N 2.91Å; F368-R370 VanDerWaalsContact C-N 3.29Å; F368-R370 PolarHBondContact O-N 2.95Å; F368-I371 WeakPolarHBondContact O-CB 3.47Å; F368-I371 PolarHBondContact O-N 3.36Å; F368-I371 VanDerWaalsContact O-N 3.12Å; F368-L372 HydrophobicContact CD1-CD1 3.68Å; F368-L372 HydrophobicContact CD1-CG 4.01Å; F368-L372 HydrophobicContact CE1-CD1 3.56Å; F368-L372 HydrophobicContact CE1-CD2 3.83Å; F368-L372 HydrophobicContact CE1-CG 3.73Å; F368-L372 HydrophobicContact CZ-CD2 4.01Å; F368-L372 HydrophobicContact CZ-CG 4.24Å; F368-L372 WeakPolarHBondContact O-CG 3.35Å; F368-L372 PolarHBondContact O-N 3.25Å
369	G	96.1	Very high	96.4	Very high	0 Å²	0	34.4 Å²	34.4	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-55.1	-42.9	170.9	0	0	0	0	0	113.5	F362 F365 G366 L367 I371 L372 C373	F362-G369 WeakPolarHBondContact CB-O 3.27Å; F362-G369 WeakPolarHBondContact O-CA 3.27Å; F365-G369 PolarHBondContact O-N 3Å; G366-G369 PolarHBondContact O-N 3.13Å; L367-G369 VanDerWaalsContact C-N 3.31Å; L367-G369 PolarHBondContact O-N 3.19Å; G369-I371 VanDerWaalsContact C-N 3.34Å; G369-I371 PolarHBondContact O-N 2.91Å; G369-L372 PolarHBondContact O-N 3.29Å; G369-C373 WeakPolarHBondContact O-CB 3.26Å; G369-C373 PolarHBondContact O-N 3.22Å
370	R	97.2	Very high	96.5	Very high	81 Å²	81	34.2 Å²	34.2	31%	0.306	18%	0.179	S	C	.	.	H	α-helix	trans	-60.5	-42.6	174.7	-169.2	-178	-177.4	-166	9.2	112.7	S169 C170 A171 Y172 L174 G366 L367 F368 C373 A374	S169-R370 WeakPolarHBondContact O-CG 3.34Å; S169-R370 PolarHBondContact O-NE 2.87Å; C170-R370 PolarHBondContact O-NH2 3.43Å; A171-R370 PolarHBondContact O-NH2 3.42Å; Y172-R370 PolarHBondContact O-NH2 2.89Å; L174-R370 HydrophobicContact CD1-CB 4.42Å; G366-R370 PolarHBondContact O-N 3.45Å; L367-R370 WeakPolarHBondContact O-CB 3.46Å; L367-R370 PolarHBondContact O-N 2.92Å; F368-R370 VanDerWaalsContact C-N 3.29Å; F368-R370 PolarHBondContact O-N 2.95Å; R370-C373 PolarHBondContact O-N 3.49Å; R370-A374 PolarHBondContact O-N 3.36Å
371	I	98	Very high	96.7	Very high	84 Å²	84	34.8 Å²	34.8	43%	0.431	18%	0.183	S	C	.	.	H	α-helix	trans	-62.3	-45.4	175.8	-63.6	169.9	0	0	0	110.4	L367 F368 G369 C373 A374 L375	L367-I371 PolarHBondContact O-N 2.96Å; F368-I371 WeakPolarHBondContact O-CB 3.47Å; F368-I371 PolarHBondContact O-N 3.36Å; F368-I371 VanDerWaalsContact O-N 3.12Å; G369-I371 VanDerWaalsContact C-N 3.34Å; G369-I371 PolarHBondContact O-N 2.91Å; I371-C373 VanDerWaalsContact C-N 3.34Å; I371-C373 PolarHBondContact O-N 2.97Å; I371-A374 PolarHBondContact O-N 3.47Å; I371-L375 HydrophobicContact CG2-CD1 4.04Å; I371-L375 HydrophobicContact CG2-CG 4.38Å; I371-L375 WeakPolarHBondContact O-CG 3.29Å; I371-L375 PolarHBondContact O-N 3.13Å
372	L	97.8	Very high	96.9	Very high	0 Å²	0	34.9 Å²	34.9	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-61.3	-41.4	177.2	-67.3	170.6	0	0	0	112.5	F234 W238 F362 F368 G369 L375 F376	F234-L372 HydrophobicContact CE1-CD2 3.91Å; W238-L372 HydrophobicContact CD2-CD1 3.78Å; W238-L372 HydrophobicContact CD2-CD2 4.12Å; W238-L372 VanDerWaalsContact CE2-CD1 3.42Å; W238-L372 HydrophobicContact CE3-CD1 3.96Å; W238-L372 HydrophobicContact CE3-CD2 4.28Å; W238-L372 HydrophobicContact CG-CD2 4.35Å; W238-L372 HydrophobicContact CH2-CD1 3.49Å; W238-L372 VanDerWaalsContact CH2-CD1 3.49Å; W238-L372 HydrophobicContact CZ2-CD1 3.25Å; W238-L372 HydrophobicContact CZ3-CD1 3.85Å; F362-L372 HydrophobicContact CD1-CB 3.79Å; F362-L372 HydrophobicContact CD1-CD1 4.03Å; F362-L372 HydrophobicContact CE1-CB 3.8Å; F362-L372 HydrophobicContact CE1-CD1 4.04Å; F362-L372 HydrophobicContact CG-CB 4.24Å; F362-L372 HydrophobicContact CZ-CB 4.2Å; F368-L372 HydrophobicContact CD1-CD1 3.68Å; F368-L372 HydrophobicContact CD1-CG 4.01Å; F368-L372 HydrophobicContact CE1-CD1 3.56Å; F368-L372 HydrophobicContact CE1-CD2 3.83Å; F368-L372 HydrophobicContact CE1-CG 3.73Å; F368-L372 HydrophobicContact CZ-CD2 4.01Å; F368-L372 HydrophobicContact CZ-CG 4.24Å; F368-L372 WeakPolarHBondContact O-CG 3.35Å; F368-L372 PolarHBondContact O-N 3.25Å; G369-L372 PolarHBondContact O-N 3.29Å; L372-L375 PolarHBondContact O-N 3.41Å; L372-F376 WeakPolarHBondContact O-CB 3.15Å; L372-F376 PolarHBondContact O-N 3.42Å
373	C	98.1	Very high	97	Very high	0 Å²	0	34.8 Å²	34.8	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-62.6	-45.9	176.8	-162	0	0	0	0	111.2	S169 L174 F362 G369 R370 I371 L375 F376 F377	S169-C373 PolarHBondContact OG-SG 3.04Å; L174-C373 HydrophobicContact CD1-CB 3.83Å; L174-C373 HydrophobicContact CD2-CB 4.2Å; F362-C373 HydrophobicContact CB-CB 3.97Å; F362-C373 HydrophobicContact CD2-CB 3.71Å; F362-C373 HydrophobicContact CG-CB 4.17Å; G369-C373 WeakPolarHBondContact O-CB 3.26Å; G369-C373 PolarHBondContact O-N 3.22Å; R370-C373 PolarHBondContact O-N 3.49Å; I371-C373 VanDerWaalsContact C-N 3.34Å; I371-C373 PolarHBondContact O-N 2.97Å; C373-L375 PolarHBondContact O-N 2.99Å; C373-F376 WeakPolarHBondContact O-CB 3.47Å; C373-F376 PolarHBondContact O-N 3.2Å; C373-F377 WeakPolarHBondContact O-CD2 3.26Å; C373-F377 PolarHBondContact O-N 2.59Å; C373-F377 VanDerWaalsContact O-N 3.08Å
374	A	98.5	Very high	97	Very high	13 Å²	13	33.5 Å²	33.5	11%	0.107	17%	0.174	C	C	.	.	H	α-helix	trans	-61.5	-44.2	175.6	0	0	0	0	0	111.8	F166 R370 I371 F376 F377 L378	F166-A374 HydrophobicContact CD2-CB 4.35Å; F166-A374 VanDerWaalsContact CD2-O 3.23Å; F166-A374 WeakPolarHBondContact CD2-O 3.43Å; F166-A374 HydrophobicContact CE2-CB 4.2Å; R370-A374 PolarHBondContact O-N 3.36Å; I371-A374 PolarHBondContact O-N 3.47Å; A374-F376 PolarHBondContact O-N 2.85Å; A374-F377 PolarHBondContact O-N 3.19Å; A374-L378 VanDerWaalsContact O-CB 3.23Å; A374-L378 WeakPolarHBondContact O-CB 3.48Å; A374-L378 PolarHBondContact O-N 3.47Å
375	L	98.3	Very high	97.2	Very high	43 Å²	43	29.5 Å²	29.5	23%	0.225	16%	0.157	C	C	.	.	H	α-helix	trans	-61.5	-43	175.8	-72.4	174.8	0	0	0	111.8	I231 F234 I371 L372 C373 F377 L378 C379	I231-L375 HydrophobicContact CD1-CD2 4.42Å; I231-L375 HydrophobicContact CG1-CD2 4.29Å; I231-L375 HydrophobicContact CG2-CB 3.94Å; I231-L375 WeakPolarHBondContact CG2-O 3.3Å; F234-L375 HydrophobicContact CD1-CD1 3.96Å; F234-L375 HydrophobicContact CE1-CD1 3.68Å; I371-L375 HydrophobicContact CG2-CD1 4.04Å; I371-L375 HydrophobicContact CG2-CG 4.38Å; I371-L375 WeakPolarHBondContact O-CG 3.29Å; I371-L375 PolarHBondContact O-N 3.13Å; L372-L375 PolarHBondContact O-N 3.41Å; C373-L375 PolarHBondContact O-N 2.99Å; L375-F377 PolarHBondContact O-N 3.4Å; L375-L378 PolarHBondContact O-N 3.02Å; L375-C379 WeakPolarHBondContact O-CB 3.27Å; L375-C379 PolarHBondContact O-N 2.87Å
376	F	98	Very high	97.3	Very high	6 Å²	6	27.3 Å²	27.3	3%	0.026	15%	0.148	C	C	.	.	H	α-helix	trans	-58.6	-50.1	178	-178.6	-102	0	0	0	112.3	I76 M235 I319 T354 I358 F362 L372 C373 A374 C379 L380	I76-F376 HydrophobicContact CG2-CD2 4.45Å; I76-F376 HydrophobicContact CG2-CE2 3.66Å; I76-F376 HydrophobicContact CG2-CZ 4.08Å; M235-F376 HydrophobicContact CE-CB 3.73Å; M235-F376 HydrophobicContact CE-CD2 3.71Å; M235-F376 HydrophobicContact CE-CG 4.13Å; M235-F376 HydrophobicContact SD-CB 3.86Å; M235-F376 HydrophobicContact SD-CD2 4.03Å; M235-F376 HydrophobicContact SD-CG 4.46Å; I319-F376 HydrophobicContact CD1-CE2 3.84Å; I319-F376 HydrophobicContact CD1-CZ 4.1Å; T354-F376 HydrophobicContact CG2-CE1 3.84Å; T354-F376 HydrophobicContact CG2-CZ 4.27Å; I358-F376 HydrophobicContact CB-CE1 4.41Å; I358-F376 HydrophobicContact CG1-CE1 4.23Å; I358-F376 HydrophobicContact CG1-CZ 4.37Å; I358-F376 HydrophobicContact CG2-CD1 3.76Å; I358-F376 HydrophobicContact CG2-CE1 3.9Å; I358-F376 HydrophobicContact CG2-CG 4.27Å; F362-F376 HydrophobicContact CE2-CB 4.04Å; F362-F376 HydrophobicContact CE2-CG 4.31Å; L372-F376 WeakPolarHBondContact O-CB 3.15Å; L372-F376 PolarHBondContact O-N 3.42Å; C373-F376 WeakPolarHBondContact O-CB 3.47Å; C373-F376 PolarHBondContact O-N 3.2Å; A374-F376 PolarHBondContact O-N 2.85Å; F376-C379 WeakPolarHBondContact O-CB 3.3Å; F376-C379 PolarHBondContact O-N 3.49Å; F376-L380 HydrophobicContact CD1-CD1 4.07Å; F376-L380 HydrophobicContact CE1-CD1 3.57Å; F376-L380 HydrophobicContact CE1-CG 4.48Å; F376-L380 HydrophobicContact CZ-CD1 4.05Å; F376-L380 PolarHBondContact O-N 3.07Å; F376-L380 VanDerWaalsContact O-N 3.11Å
377	F	98	Very high	97.5	Very high	0 Å²	0	25.2 Å²	25.2	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-71.4	-32.1	178.2	-75.1	-70.8	0	0	0	112.6	Y165 F166 T354 F355 P359 C373 A374 L375 C379 L380 V381	Y165-F377 VanDerWaalsContact CB-CD1 3.42Å; Y165-F377 HydrophobicContact CD1-CE1 4.05Å; Y165-F377 AromaticContact CD1-CE2 3.83Å; Y165-F377 HydrophobicContact CD1-CE2 3.83Å; Y165-F377 AromaticContact CD1-CZ 3.47Å; Y165-F377 HydrophobicContact CD1-CZ 3.47Å; Y165-F377 VanDerWaalsContact CD1-CZ 3.47Å; Y165-F377 HydrophobicContact CE1-CZ 4.41Å; Y165-F377 HydrophobicContact CG-CD1 4.35Å; Y165-F377 AromaticContact CG-CE1 3.81Å; Y165-F377 HydrophobicContact CG-CE1 3.81Å; Y165-F377 HydrophobicContact CG-CE2 4.19Å; Y165-F377 AromaticContact CG-CZ 3.72Å; Y165-F377 HydrophobicContact CG-CZ 3.72Å; F166-F377 HydrophobicContact CB-CB 3.85Å; T354-F377 HydrophobicContact CG2-CE1 4.22Å; F355-F377 AromaticContact CD1-CE1 3.88Å; F355-F377 HydrophobicContact CD1-CE1 3.88Å; F355-F377 HydrophobicContact CD1-CZ 4.37Å; F355-F377 AromaticContact CE1-CE1 3.79Å; F355-F377 HydrophobicContact CE1-CE1 3.79Å; P359-F377 HydrophobicContact CG-CE2 4.12Å; P359-F377 HydrophobicContact CG-CZ 4.33Å; C373-F377 WeakPolarHBondContact O-CD2 3.26Å; C373-F377 PolarHBondContact O-N 2.59Å; C373-F377 VanDerWaalsContact O-N 3.08Å; A374-F377 PolarHBondContact O-N 3.19Å; L375-F377 PolarHBondContact O-N 3.4Å; F377-C379 VanDerWaalsContact C-N 3.31Å; F377-C379 PolarHBondContact O-N 3.01Å; F377-L380 HydrophobicContact CD1-CD1 3.83Å; F377-L380 HydrophobicContact CE1-CD1 4.1Å; F377-L380 WeakPolarHBondContact O-CB 3.33Å; F377-L380 PolarHBondContact O-N 3.34Å; F377-V381 VanDerWaalsContact O-CG2 3.31Å; F377-V381 WeakPolarHBondContact O-CG2 3.2Å; F377-V381 PolarHBondContact O-N 2.91Å
378	L	98.4	Very high	97.6	Very high	43 Å²	43	19.1 Å²	19.1	23%	0.225	9%	0.093	C	C	.	.	H	α-helix	trans	-61	-42.1	170.7	-178.6	60.3	0	0	0	111.4	F166 I231 A374 L375 L380 V381 C382	F166-L378 HydrophobicContact CD2-CB 3.88Å; F166-L378 HydrophobicContact CE1-CD1 4.41Å; F166-L378 HydrophobicContact CE2-CB 3.74Å; F166-L378 HydrophobicContact CE2-CD1 4.24Å; F166-L378 HydrophobicContact CE2-CD2 4.4Å; F166-L378 HydrophobicContact CE2-CG 4.35Å; F166-L378 HydrophobicContact CZ-CB 4.44Å; F166-L378 HydrophobicContact CZ-CD1 4.09Å; I231-L378 HydrophobicContact CD1-CB 4.38Å; I231-L378 HydrophobicContact CD1-CD2 3.99Å; I231-L378 HydrophobicContact CD1-CG 4.05Å; A374-L378 VanDerWaalsContact O-CB 3.23Å; A374-L378 WeakPolarHBondContact O-CB 3.48Å; A374-L378 PolarHBondContact O-N 3.47Å; L375-L378 PolarHBondContact O-N 3.02Å; L378-L380 VanDerWaalsContact C-N 3.35Å; L378-L380 PolarHBondContact O-N 3.09Å; L378-V381 PolarHBondContact O-N 3.39Å; L378-C382 PolarHBondContact O-N 3.31Å; L378-C382 PolarHBondContact O-SG 3.14Å; L378-C382 VanDerWaalsContact O-SG 3.33Å
379	C	98.4	Very high	97.7	Very high	2 Å²	2	15 Å²	15	1%	0.014	8%	0.075	C	C	.	.	H	α-helix	trans	-59.8	-45.3	175.3	-174.4	0	0	0	0	111.6	I76 I231 I232 L375 F376 F377 V381 C382 A383	I76-C379 VanDerWaalsContact CD1-SG 3.54Å; I231-C379 HydrophobicContact CB-CB 4.13Å; I231-C379 HydrophobicContact CD1-CB 4.33Å; I231-C379 HydrophobicContact CG2-CB 3.72Å; I232-C379 WeakPolarHBondContact CG1-SG 3.43Å; L375-C379 WeakPolarHBondContact O-CB 3.27Å; L375-C379 PolarHBondContact O-N 2.87Å; F376-C379 WeakPolarHBondContact O-CB 3.3Å; F376-C379 PolarHBondContact O-N 3.49Å; F377-C379 VanDerWaalsContact C-N 3.31Å; F377-C379 PolarHBondContact O-N 3.01Å; C379-V381 PolarHBondContact O-N 3.08Å; C379-C382 PolarHBondContact O-N 3.39Å; C379-A383 WeakPolarHBondContact O-CB 3.25Å; C379-A383 PolarHBondContact O-N 3.18Å
380	L	97.6	Very high	97.7	Very high	0 Å²	0	15 Å²	15	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-60.5	-42.6	173.5	-73.7	170.2	0	0	0	112.1	T73 I76 W77 C162 T354 F376 F377 L378 A383 G384	T73-L380 HydrophobicContact CG2-CB 4.45Å; T73-L380 HydrophobicContact CG2-CD2 4.24Å; T73-L380 WeakPolarHBondContact CG2-O 3.48Å; I76-L380 HydrophobicContact CB-CD2 3.67Å; I76-L380 HydrophobicContact CD1-CD2 4.14Å; I76-L380 HydrophobicContact CG2-CD2 3.83Å; I76-L380 HydrophobicContact CG2-CG 4.26Å; W77-L380 HydrophobicContact CB-CD2 4Å; W77-L380 HydrophobicContact CG-CD2 4.36Å; C162-L380 HydrophobicContact CB-CB 3.95Å; T354-L380 HydrophobicContact CG2-CD1 4Å; F376-L380 HydrophobicContact CD1-CD1 4.07Å; F376-L380 HydrophobicContact CE1-CD1 3.57Å; F376-L380 HydrophobicContact CE1-CG 4.48Å; F376-L380 HydrophobicContact CZ-CD1 4.05Å; F376-L380 PolarHBondContact O-N 3.07Å; F376-L380 VanDerWaalsContact O-N 3.11Å; F377-L380 HydrophobicContact CD1-CD1 3.83Å; F377-L380 HydrophobicContact CE1-CD1 4.1Å; F377-L380 WeakPolarHBondContact O-CB 3.33Å; F377-L380 PolarHBondContact O-N 3.34Å; L378-L380 VanDerWaalsContact C-N 3.35Å; L378-L380 PolarHBondContact O-N 3.09Å; L380-A383 PolarHBondContact O-N 3.37Å; L380-G384 PolarHBondContact O-N 3.13Å
381	V	98.2	Very high	97.7	Very high	15 Å²	15	11.6 Å²	11.6	9%	0.091	6%	0.063	C	C	.	.	H	α-helix	trans	-61.9	-45.6	176.6	171.4	0	0	0	0	111	L159 C162 I163 F377 L378 C379 G384 I385	L159-V381 HydrophobicContact CD1-CB 4.45Å; L159-V381 HydrophobicContact CD1-CG1 4.45Å; L159-V381 HydrophobicContact CD1-CG2 4.45Å; C162-V381 HydrophobicContact CB-CG2 3.87Å; I163-V381 HydrophobicContact CB-CG2 4.41Å; I163-V381 HydrophobicContact CG1-CG1 4.18Å; I163-V381 HydrophobicContact CG1-CG2 3.75Å; F377-V381 VanDerWaalsContact O-CG2 3.31Å; F377-V381 WeakPolarHBondContact O-CG2 3.2Å; F377-V381 PolarHBondContact O-N 2.91Å; L378-V381 PolarHBondContact O-N 3.39Å; C379-V381 PolarHBondContact O-N 3.08Å; V381-G384 PolarHBondContact O-N 2.81Å; V381-I385 HydrophobicContact CG1-CD1 3.75Å; V381-I385 HydrophobicContact CG1-CG1 4.39Å; V381-I385 WeakPolarHBondContact O-CG1 3.42Å; V381-I385 PolarHBondContact O-N 2.75Å
382	C	98.3	Very high	97.7	Very high	4 Å²	4	7.8 Å²	7.8	3%	0.027	4%	0.044	C	C	.	.	H	α-helix	trans	-60.7	-48.6	177.2	-67.4	0	0	0	0	111.9	L224 L228 L378 C379 G384 I385 S386	L224-C382 HydrophobicContact CD2-CB 4.26Å; L228-C382 HydrophobicContact CB-CB 3.84Å; L378-C382 PolarHBondContact O-N 3.31Å; L378-C382 PolarHBondContact O-SG 3.14Å; L378-C382 VanDerWaalsContact O-SG 3.33Å; C379-C382 PolarHBondContact O-N 3.39Å; C382-G384 VanDerWaalsContact C-N 3.29Å; C382-G384 PolarHBondContact O-N 2.96Å; C382-I385 PolarHBondContact O-N 3.31Å; C382-S386 PolarHBondContact O-N 2.92Å; C382-S386 VanDerWaalsContact O-N 3.09Å; C382-S386 PolarHBondContact O-OG 3.44Å
383	A	97.8	Very high	97.6	Very high	0 Å²	0	8 Å²	8	0%	0	5%	0.045	C	C	.	.	H	α-helix	trans	-63.1	-35.3	177.9	0	0	0	0	0	112.5	I76 L228 C379 L380 S386 S387	I76-A383 HydrophobicContact CD1-CB 3.92Å; L228-A383 HydrophobicContact CD2-CB 4.27Å; C379-A383 WeakPolarHBondContact O-CB 3.25Å; C379-A383 PolarHBondContact O-N 3.18Å; L380-A383 PolarHBondContact O-N 3.37Å; A383-S386 PolarHBondContact O-OG 3.47Å; A383-S386 VanDerWaalsContact O-OG 3.12Å; A383-S387 WeakPolarHBondContact O-CB 3.35Å; A383-S387 PolarHBondContact O-N 3.28Å; A383-S387 PolarHBondContact O-OG 3.24Å
384	G	96.9	Very high	97.6	Very high	0 Å²	0	8 Å²	8	0%	0	5%	0.045	C	C	.	.	H	α-helix	trans	-74.8	-37.8	178.5	0	0	0	0	0	113.7	Y155 L380 V381 C382 S387 L388	Y155-G384 WeakPolarHBondContact CE1-O 3.3Å; Y155-G384 WeakPolarHBondContact OH-CA 3.34Å; L380-G384 PolarHBondContact O-N 3.13Å; V381-G384 PolarHBondContact O-N 2.81Å; C382-G384 VanDerWaalsContact C-N 3.29Å; C382-G384 PolarHBondContact O-N 2.96Å; G384-S387 PolarHBondContact O-OG 2.75Å; G384-S387 VanDerWaalsContact O-OG 3.05Å; G384-L388 WeakPolarHBondContact O-CB 3.09Å; G384-L388 PolarHBondContact O-N 2.84Å
385	I	97.8	Very high	97.6	Very high	17 Å²	17	8.1 Å²	8.1	9%	0.087	5%	0.047	C	C	.	.	H	α-helix	trans	-67.6	-46.7	175.7	-66.8	170.5	0	0	0	109.9	L159 L205 L224 V381 C382 S387 L388 L389	L159-I385 HydrophobicContact CD1-CG1 4.47Å; L159-I385 HydrophobicContact CD2-CG1 3.95Å; L205-I385 HydrophobicContact CB-CD1 4.45Å; L205-I385 HydrophobicContact CD1-CD1 4.42Å; L224-I385 HydrophobicContact CD1-CB 4.18Å; L224-I385 HydrophobicContact CD1-CG2 3.73Å; V381-I385 HydrophobicContact CG1-CD1 3.75Å; V381-I385 HydrophobicContact CG1-CG1 4.39Å; V381-I385 WeakPolarHBondContact O-CG1 3.42Å; V381-I385 PolarHBondContact O-N 2.75Å; C382-I385 PolarHBondContact O-N 3.31Å; I385-S387 VanDerWaalsContact C-N 3.33Å; I385-S387 PolarHBondContact O-N 3.31Å; I385-L388 PolarHBondContact O-N 2.89Å; I385-L389 HydrophobicContact CG2-CD1 4.14Å; I385-L389 HydrophobicContact CG2-CG 4.37Å; I385-L389 VanDerWaalsContact O-CG 3.23Å; I385-L389 WeakPolarHBondContact O-CG 3.4Å; I385-L389 PolarHBondContact O-N 3.39Å
386	S	97.2	Very high	97.5	Very high	0 Å²	0	6.1 Å²	6.1	0%	0	4%	0.037	C	C	.	.	H	α-helix	trans	-61.5	-39.8	-178.8	61	0	0	0	0	112.9	G68 N221 C382 A383 S390	G68-S386 CarbonylContact O-C 3.5Å; G68-S386 WeakPolarHBondContact O-CB 3.32Å; G68-S386 PolarHBondContact O-OG 3.46Å; N221-S386 VanDerWaalsContact OD1-CB 3.27Å; N221-S386 WeakPolarHBondContact OD1-CB 3.41Å; C382-S386 PolarHBondContact O-N 2.92Å; C382-S386 VanDerWaalsContact O-N 3.09Å; C382-S386 PolarHBondContact O-OG 3.44Å; A383-S386 PolarHBondContact O-OG 3.47Å; A383-S386 VanDerWaalsContact O-OG 3.12Å; S386-S390 PolarHBondContact O-N 3.1Å; S386-S390 PolarHBondContact O-OG 2.92Å
387	S	96.2	Very high	97.4	Very high	5 Å²	5	6 Å²	6	4%	0.035	4%	0.036	C	C	.	.	H	α-helix	trans	-72.8	-42.2	177.7	64.5	0	0	0	0	111.9	G68 Y155 A383 G384 I385 L389 S390 I391	G68-S387 PolarHBondContact O-N 3.01Å; Y155-S387 WeakPolarHBondContact CE1-OG 3.2Å; Y155-S387 VanDerWaalsContact CZ-OG 3.24Å; Y155-S387 PolarHBondContact OH-OG 3.45Å; A383-S387 WeakPolarHBondContact O-CB 3.35Å; A383-S387 PolarHBondContact O-N 3.28Å; A383-S387 PolarHBondContact O-OG 3.24Å; G384-S387 PolarHBondContact O-OG 2.75Å; G384-S387 VanDerWaalsContact O-OG 3.05Å; I385-S387 VanDerWaalsContact C-N 3.33Å; I385-S387 PolarHBondContact O-N 3.31Å; S387-L389 VanDerWaalsContact C-N 3.31Å; S387-L389 PolarHBondContact O-N 3.49Å; S387-S390 WeakPolarHBondContact O-CA 3.47Å; S387-S390 VanDerWaalsContact O-CB 3.3Å; S387-S390 WeakPolarHBondContact O-CB 3.32Å; S387-S390 PolarHBondContact O-N 2.83Å; S387-I391 WeakPolarHBondContact O-CB 3.49Å; S387-I391 WeakPolarHBondContact O-CG1 3.46Å; S387-I391 PolarHBondContact O-N 3.49Å
388	L	97.1	Very high	97.4	Very high	1 Å²	1	6.4 Å²	6.4	1%	0.005	4%	0.04	C	C	.	.	H	α-helix	trans	-65.4	-34.5	178.9	-175.3	58.6	0	0	0	112	Y155 P156 L159 T206 G384 I385 S390 I391 T392	Y155-L388 HydrophobicContact CD1-CB 4.08Å; Y155-L388 HydrophobicContact CD1-CD1 4.15Å; Y155-L388 HydrophobicContact CE1-CB 4.14Å; P156-L388 HydrophobicContact CB-CD2 4.05Å; P156-L388 HydrophobicContact CG-CD1 3.98Å; P156-L388 HydrophobicContact CG-CD2 3.73Å; L159-L388 HydrophobicContact CD2-CD2 4.12Å; T206-L388 HydrophobicContact CG2-CB 4.27Å; T206-L388 HydrophobicContact CG2-CD2 4.18Å; T206-L388 HydrophobicContact CG2-CG 3.9Å; T206-L388 WeakPolarHBondContact OG1-CD2 3.37Å; G384-L388 WeakPolarHBondContact O-CB 3.09Å; G384-L388 PolarHBondContact O-N 2.84Å; I385-L388 PolarHBondContact O-N 2.89Å; L388-S390 VanDerWaalsContact C-N 3.3Å; L388-S390 PolarHBondContact O-N 3.13Å; L388-I391 HydrophobicContact CD1-CG2 4.35Å; L388-T392 WeakPolarHBondContact O-CB 3.35Å; L388-T392 PolarHBondContact O-N 3.06Å; L388-T392 PolarHBondContact O-OG1 3.1Å
389	L	97.1	Very high	97.2	Very high	0 Å²	0	6.4 Å²	6.4	0%	0	4%	0.039	C	C	.	.	H	α-helix	trans	-56.6	-46.5	169.9	-74.3	171.7	0	0	0	111.3	T206 C209 L210 A220 I385 S387 Q393	T206-L389 HydrophobicContact CG2-CD2 3.54Å; T206-L389 HydrophobicContact CG2-CG 3.91Å; T206-L389 VanDerWaalsContact O-CD2 3.22Å; T206-L389 WeakPolarHBondContact O-CD2 3.31Å; C209-L389 HydrophobicContact CB-CD1 3.99Å; C209-L389 HydrophobicContact CB-CD2 3.66Å; C209-L389 HydrophobicContact CB-CG 4.45Å; L210-L389 HydrophobicContact CB-CD2 3.91Å; A220-L389 HydrophobicContact CB-CD1 4.16Å; I385-L389 HydrophobicContact CG2-CD1 4.14Å; I385-L389 HydrophobicContact CG2-CG 4.37Å; I385-L389 VanDerWaalsContact O-CG 3.23Å; I385-L389 WeakPolarHBondContact O-CG 3.4Å; I385-L389 PolarHBondContact O-N 3.39Å; S387-L389 VanDerWaalsContact C-N 3.31Å; S387-L389 PolarHBondContact O-N 3.49Å; L389-Q393 VanDerWaalsContact O-CB 3.29Å; L389-Q393 WeakPolarHBondContact O-CB 3.46Å; L389-Q393 PolarHBondContact O-N 3.2Å; L389-Q393 VanDerWaalsContact O-N 3.07Å
390	S	97.1	Very high	97	Very high	0 Å²	0	10.3 Å²	10.3	0%	0	6%	0.056	C	C	.	.	H	α-helix	trans	-65.9	-47.8	-178.5	-53.7	0	0	0	0	111.9	G69 Y287 S386 S387 L388 Q393	G69-S390 WeakPolarHBondContact CA-OG 3.33Å; Y287-S390 WeakPolarHBondContact CE2-OG 3.41Å; Y287-S390 VanDerWaalsContact OH-CA 3.29Å; Y287-S390 WeakPolarHBondContact OH-CA 3.34Å; Y287-S390 WeakPolarHBondContact OH-CB 3.44Å; Y287-S390 PolarHBondContact OH-OG 2.87Å; S386-S390 PolarHBondContact O-N 3.1Å; S386-S390 PolarHBondContact O-OG 2.92Å; S387-S390 WeakPolarHBondContact O-CA 3.47Å; S387-S390 VanDerWaalsContact O-CB 3.3Å; S387-S390 WeakPolarHBondContact O-CB 3.32Å; S387-S390 PolarHBondContact O-N 2.83Å; L388-S390 VanDerWaalsContact C-N 3.3Å; L388-S390 PolarHBondContact O-N 3.13Å; S390-Q393 PolarHBondContact O-N 3.46Å
391	I	97	Very high	96.8	Very high	10 Å²	10	11.8 Å²	11.8	5%	0.051	6%	0.063	C	C	.	.	H	α-helix	trans	-57.3	-50	176.6	-78.8	164.1	0	0	0	111	V148 L151 S152 I283 S387 L388 Q393 I394	V148-I391 HydrophobicContact CG1-CB 4.09Å; V148-I391 HydrophobicContact CG1-CG1 4.17Å; V148-I391 HydrophobicContact CG1-CG2 3.62Å; L151-I391 HydrophobicContact CD2-CD1 3.97Å; S152-I391 VanDerWaalsContact CB-CG2 3.43Å; I283-I391 HydrophobicContact CD1-CG1 4.04Å; S387-I391 WeakPolarHBondContact O-CB 3.49Å; S387-I391 WeakPolarHBondContact O-CG1 3.46Å; S387-I391 PolarHBondContact O-N 3.49Å; L388-I391 HydrophobicContact CD1-CG2 4.35Å; I391-Q393 VanDerWaalsContact C-N 3.34Å; I391-Q393 PolarHBondContact O-N 3.02Å; I391-I394 WeakPolarHBondContact O-CB 3.4Å; I391-I394 PolarHBondContact O-N 3.38Å
392	T	97.5	Very high	96.5	Very high	5 Å²	5	13.3 Å²	13.3	3%	0.031	7%	0.07	C	C	.	.	H	α-helix	trans	-67.7	-35.9	-177	-50.4	0	0	0	0	111.6	L210 L388 I394 G395 V396 A413 L414	L210-T392 HydrophobicContact CD2-CG2 3.43Å; L210-T392 VanDerWaalsContact CD2-CG2 3.43Å; L388-T392 WeakPolarHBondContact O-CB 3.35Å; L388-T392 PolarHBondContact O-N 3.06Å; L388-T392 PolarHBondContact O-OG1 3.1Å; T392-I394 PolarHBondContact O-N 2.69Å; T392-G395 PolarHBondContact O-N 3.46Å; T392-V396 HydrophobicContact CG2-CG2 4.28Å; T392-V396 WeakPolarHBondContact O-CG2 3.14Å; T392-V396 PolarHBondContact O-N 2.76Å; T392-V396 VanDerWaalsContact O-N 3.13Å; T392-A413 HydrophobicContact CG2-CB 3.77Å; T392-L414 HydrophobicContact CG2-CD2 3.92Å; T392-L414 HydrophobicContact CG2-CG 4.34Å
393	Q	97.1	Very high	96.2	Very high	4 Å²	4	17.2 Å²	17.2	2%	0.019	9%	0.091	C	C	.	.	H	α-helix	trans	-62.8	-24.6	-178.6	-177.2	53.9	56.4	0	0	113.3	L210 I217 T286 Y287 L389 S390 I391 L397	L210-Q393 HydrophobicContact CD1-CB 4.16Å; L210-Q393 VanDerWaalsContact CD1-OE1 3.28Å; I217-Q393 HydrophobicContact CD1-CB 4.11Å; I217-Q393 HydrophobicContact CD1-CG 3.87Å; T286-Q393 HydrophobicContact CG2-CG 3.93Å; Y287-Q393 HydrophobicContact CE1-CB 4.45Å; Y287-Q393 HydrophobicContact CE1-CG 4.22Å; L389-Q393 VanDerWaalsContact O-CB 3.29Å; L389-Q393 WeakPolarHBondContact O-CB 3.46Å; L389-Q393 PolarHBondContact O-N 3.2Å; L389-Q393 VanDerWaalsContact O-N 3.07Å; S390-Q393 PolarHBondContact O-N 3.46Å; I391-Q393 VanDerWaalsContact C-N 3.34Å; I391-Q393 PolarHBondContact O-N 3.02Å; Q393-L397 WeakPolarHBondContact O-CB 3.14Å; Q393-L397 PolarHBondContact O-N 3.22Å
394	I	97.8	Very high	96	Very high	1 Å²	1	19 Å²	19	1%	0.005	10%	0.101	C	C	.	.	H	α-helix	trans	-60.7	-53.2	174.1	-66.9	158.7	0	0	0	110.6	V145 V148 M281 I283 T286 I391 T392 L397 A398	V145-I394 HydrophobicContact CG2-CG2 3.99Å; V148-I394 HydrophobicContact CB-CD1 4.41Å; V148-I394 HydrophobicContact CG1-CD1 3.7Å; V148-I394 HydrophobicContact CG2-CD1 4.44Å; M281-I394 WeakPolarHBondContact O-CD1 3.41Å; I283-I394 HydrophobicContact CB-CD1 4.34Å; I283-I394 HydrophobicContact CG1-CD1 3.55Å; I283-I394 HydrophobicContact CG1-CG1 4.49Å; T286-I394 HydrophobicContact CG2-CG1 4.44Å; T286-I394 WeakPolarHBondContact OG1-CG1 3.36Å; I391-I394 WeakPolarHBondContact O-CB 3.4Å; I391-I394 PolarHBondContact O-N 3.38Å; T392-I394 PolarHBondContact O-N 2.69Å; I394-L397 PolarHBondContact O-N 2.86Å; I394-A398 PolarHBondContact O-N 3.41Å; I394-A398 VanDerWaalsContact O-N 3.14Å
395	G	97.4	Very high	95.9	Very high	15 Å²	15	22.5 Å²	22.5	16%	0.155	13%	0.126	C	C	.	.	H	α-helix	trans	-66.3	-38.4	178.9	0	0	0	0	0	112.6	T392 L397 A398 M399	T392-G395 PolarHBondContact O-N 3.46Å; G395-L397 PolarHBondContact O-N 3.39Å; G395-A398 PolarHBondContact O-N 3.5Å; G395-M399 WeakPolarHBondContact O-CG 3.4Å; G395-M399 PolarHBondContact O-N 3.48Å
396	V	97.4	Very high	95.8	Very high	0 Å²	0	23.4 Å²	23.4	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-60.6	-44.7	176	172.4	0	0	0	0	111.3	L210 T392 M399 K400 A409 V410 A413	L210-V396 HydrophobicContact CD2-CG2 4.26Å; T392-V396 HydrophobicContact CG2-CG2 4.28Å; T392-V396 WeakPolarHBondContact O-CG2 3.14Å; T392-V396 PolarHBondContact O-N 2.76Å; T392-V396 VanDerWaalsContact O-N 3.13Å; V396-M399 PolarHBondContact O-N 2.6Å; V396-K400 WeakPolarHBondContact O-CB 3.02Å; V396-K400 PolarHBondContact O-N 2.83Å; V396-A409 HydrophobicContact CG1-CB 4.04Å; V396-V410 HydrophobicContact CG1-CG2 3.89Å; V396-V410 HydrophobicContact CG2-CG2 3.89Å; V396-A413 HydrophobicContact CG2-CB 4.16Å
397	L	95.8	Very high	95.7	Very high	4 Å²	4	32.9 Å²	32.9	2%	0.021	17%	0.166	C	C	.	.	H	α-helix	trans	-65.8	-41.5	178.7	-175.6	60.7	0	0	0	111.6	T286 T289 F290 Q393 I394 G395 K400 E401	T286-L397 HydrophobicContact CG2-CB 4.29Å; T286-L397 HydrophobicContact CG2-CD2 3.87Å; T289-L397 HydrophobicContact CG2-CD2 4.03Å; F290-L397 HydrophobicContact CZ-CD1 4.45Å; Q393-L397 WeakPolarHBondContact O-CB 3.14Å; Q393-L397 PolarHBondContact O-N 3.22Å; I394-L397 PolarHBondContact O-N 2.86Å; G395-L397 PolarHBondContact O-N 3.39Å; L397-K400 PolarHBondContact O-N 3.02Å; L397-E401 PolarHBondContact O-N 3.28Å
398	A	96.5	Very high	95.7	Very high	8 Å²	8	37.1 Å²	37.1	7%	0.066	19%	0.187	C	C	.	.	H	α-helix	trans	-61.1	-45.6	176.6	0	0	0	0	0	112.2	P126 V145 I394 G395 K400 E401 L402	P126-A398 HydrophobicContact CG-CB 4.16Å; V145-A398 HydrophobicContact CG1-CB 4.38Å; V145-A398 HydrophobicContact CG2-CB 4.11Å; I394-A398 PolarHBondContact O-N 3.41Å; I394-A398 VanDerWaalsContact O-N 3.14Å; G395-A398 PolarHBondContact O-N 3.5Å; A398-K400 VanDerWaalsContact C-N 3.34Å; A398-K400 PolarHBondContact O-N 3.13Å; A398-E401 PolarHBondContact O-N 3.13Å; A398-L402 PolarHBondContact O-N 3.17Å
399	M	95.8	Very high	95.7	Very high	43 Å²	43	37 Å²	37	21%	0.212	19%	0.187	C	C	.	.	H	α-helix	trans	-64.9	-37.4	175.9	-74.1	-172.3	-79.4	0	0	112.6	G395 V396 E401 L402 V404 A409 I412 A413	G395-M399 WeakPolarHBondContact O-CG 3.4Å; G395-M399 PolarHBondContact O-N 3.48Å; V396-M399 PolarHBondContact O-N 2.6Å; M399-E401 VanDerWaalsContact C-N 3.3Å; M399-E401 PolarHBondContact O-N 2.95Å; M399-L402 CarbonylContact O-C 3.54Å; M399-L402 WeakPolarHBondContact O-CA 3.42Å; M399-L402 WeakPolarHBondContact O-CB 3.46Å; M399-L402 PolarHBondContact O-N 3.44Å; M399-V404 HydrophobicContact CB-CB 4.09Å; M399-V404 HydrophobicContact CB-CG2 4.14Å; M399-V404 WeakPolarHBondContact O-CB 3.17Å; M399-V404 WeakPolarHBondContact O-CG2 3.26Å; M399-V404 PolarHBondContact O-N 3.01Å; M399-V404 VanDerWaalsContact O-N 3.14Å; M399-A409 HydrophobicContact CB-CB 3.9Å; M399-A409 HydrophobicContact CE-CB 4.05Å; M399-A409 WeakPolarHBondContact CE-O 3.29Å; M399-A409 HydrophobicContact SD-CB 4.44Å; M399-I412 HydrophobicContact CE-CG2 4.43Å; M399-I412 HydrophobicContact SD-CB 4.3Å; M399-I412 HydrophobicContact SD-CG2 3.93Å; M399-A413 HydrophobicContact CE-CB 3.94Å
400	K	94	Very high	95.7	Very high	85 Å²	85	37.4 Å²	37.4	37%	0.37	19%	0.189	S	C	.	.	H	α-helix	trans	-60.9	-39.7	179.1	-173	-179.7	174.7	-175.5	0	112.2	V396 L397 A398 L402 N403 V404	V396-K400 WeakPolarHBondContact O-CB 3.02Å; V396-K400 PolarHBondContact O-N 2.83Å; L397-K400 PolarHBondContact O-N 3.02Å; A398-K400 VanDerWaalsContact C-N 3.34Å; A398-K400 PolarHBondContact O-N 3.13Å; K400-L402 PolarHBondContact O-N 3.46Å; K400-N403 PolarHBondContact O-N 3.06Å; K400-N403 VanDerWaalsContact O-N 3.08Å; K400-V404 WeakPolarHBondContact CA-O 3.18Å
401	E	92.9	Very high	95.7	Very high	31 Å²	31	39.2 Å²	39.2	15%	0.145	20%	0.204	C	C	.	.	H	α-helix	trans	-70.3	-19.4	176.1	-68.1	-177	155.3	0	0	112.9	N123 S124 V127 L397 A398 M399 N403 A548	N123-E401 WeakPolarHBondContact CA-OE1 3.43Å; N123-E401 WeakPolarHBondContact CB-OE1 3.37Å; N123-E401 PolarHBondContact ND2-OE1 3.49Å; S124-E401 WeakPolarHBondContact CB-OE2 3.28Å; S124-E401 PolarHBondContact N-OE1 3.3Å; S124-E401 VanDerWaalsContact N-OE1 3.14Å; S124-E401 PolarHBondContact N-OE2 2.87Å; S124-E401 PolarHBondContact OG-OE2 2.9Å; V127-E401 VanDerWaalsContact CB-OE2 3.29Å; V127-E401 WeakPolarHBondContact CB-OE2 3.38Å; V127-E401 HydrophobicContact CG2-CB 4.18Å; V127-E401 WeakPolarHBondContact CG2-OE2 3.19Å; L397-E401 PolarHBondContact O-N 3.28Å; A398-E401 PolarHBondContact O-N 3.13Å; M399-E401 VanDerWaalsContact C-N 3.3Å; M399-E401 PolarHBondContact O-N 2.95Å; E401-N403 PolarHBondContact O-N 3.39Å; E401-A548 WeakPolarHBondContact O-CB 3.3Å
402	L	92.4	Very high	95.8	Very high	46 Å²	46	42.3 Å²	42.3	24%	0.241	22%	0.22	C	C	.	.	T	Hydrogen-bonded Turn	trans	-86.3	18.4	169.3	-59.1	178.4	0	0	0	113.3	F138 A398 M399 K400 L539 I544	F138-L402 HydrophobicContact CZ-CD1 4.33Å; F138-L402 HydrophobicContact CZ-CD2 4.33Å; A398-L402 PolarHBondContact O-N 3.17Å; M399-L402 CarbonylContact O-C 3.54Å; M399-L402 WeakPolarHBondContact O-CA 3.42Å; M399-L402 WeakPolarHBondContact O-CB 3.46Å; M399-L402 PolarHBondContact O-N 3.44Å; K400-L402 PolarHBondContact O-N 3.46Å; L402-L539 HydrophobicContact CD1-CD1 4.32Å; L402-L539 HydrophobicContact CD2-CD1 4.35Å; L402-L539 HydrophobicContact CD2-CD2 4.37Å; L402-I544 HydrophobicContact CD2-CG2 4.04Å
403	N	91.4	Very high	95.8	Very high	87 Å²	87	42.4 Å²	42.4	47%	0.465	22%	0.221	S	C	.	.	T	Hydrogen-bonded Turn	trans	69.6	19.1	-179.6	-50.3	-81.3	0	0	0	115.7	K400 E401 K551	K400-N403 PolarHBondContact O-N 3.06Å; K400-N403 VanDerWaalsContact O-N 3.08Å; E401-N403 PolarHBondContact O-N 3.39Å; N403-K551 PolarHBondContact OD1-NZ 2.94Å
404	V	94.1	Very high	95.7	Very high	37 Å²	37	43 Å²	43	22%	0.224	23%	0.225	C	C	.	.			trans	-79.1	132.4	168.3	-173.6	0	0	0	0	109	M399 K400 L408 A409 I412	M399-V404 HydrophobicContact CB-CB 4.09Å; M399-V404 HydrophobicContact CB-CG2 4.14Å; M399-V404 WeakPolarHBondContact O-CB 3.17Å; M399-V404 WeakPolarHBondContact O-CG2 3.26Å; M399-V404 PolarHBondContact O-N 3.01Å; M399-V404 VanDerWaalsContact O-N 3.14Å; K400-V404 WeakPolarHBondContact CA-O 3.18Å; V404-L408 HydrophobicContact CG1-CB 4.03Å; V404-L408 HydrophobicContact CG1-CD2 4Å; V404-L408 HydrophobicContact CG1-CG 3.89Å; V404-A409 HydrophobicContact CB-CB 4.38Å; V404-A409 HydrophobicContact CG1-CB 3.87Å; V404-I412 HydrophobicContact CG1-CD1 4.24Å
405	S	95.2	Very high	95.7	Very high	73 Å²	73	47.9 Å²	47.9	51%	0.51	25%	0.25	S	C	.	.			trans	-63.1	149.6	176.5	75.2	0	0	0	0	111.1	R407 L408 A409	S405-R407 PolarHBondContact O-N 2.63Å; S405-L408 PolarHBondContact O-N 2.65Å; S405-L408 VanDerWaalsContact O-N 3.16Å; S405-L408 VanDerWaalsContact OG-CB 3.25Å; S405-L408 WeakPolarHBondContact OG-CB 3.48Å; S405-A409 WeakPolarHBondContact O-CB 3.28Å; S405-A409 PolarHBondContact O-N 2.87Å
406	H	93.9	Very high	95.7	Very high	37 Å²	37	48.4 Å²	48.4	17%	0.171	25%	0.253	C	S	.	.	H	α-helix	trans	-53.9	-50.9	-175.6	-177.1	85.1	0	0	0	112.6	L210 A211 G213 L408 A409 V410	L210-H406 PolarHBondContact O-NE2 2.99Å; L210-H406 VanDerWaalsContact O-NE2 3.09Å; A211-H406 PolarHBondContact O-CD2 3.11Å; G213-H406 VanDerWaalsContact CA-CE1 3.47Å; G213-H406 WeakPolarHBondContact CA-CE1 3.46Å; G213-H406 VanDerWaalsContact CA-NE2 3.31Å; G213-H406 WeakPolarHBondContact CA-NE2 3.33Å; G213-H406 PolarHBondContact N-NE2 2.94Å; H406-L408 VanDerWaalsContact C-N 3.32Å; H406-L408 PolarHBondContact O-N 3.25Å; H406-A409 PolarHBondContact O-N 2.96Å; H406-V410 VanDerWaalsContact O-CG2 3.32Å; H406-V410 WeakPolarHBondContact O-CG2 3.27Å; H406-V410 PolarHBondContact O-N 3.4Å
407	R	95	Very high	95.7	Very high	199 Å²	199	48.4 Å²	48.4	75%	0.751	25%	0.253	S	S	*	.	H	α-helix	trans	-63.6	-37.9	-178.5	-67.9	-176.3	-179.4	171.4	0.5	112.5	S405 A411	S405-R407 PolarHBondContact O-N 2.63Å; R407-A411 WeakPolarHBondContact O-CB 3.37Å; R407-A411 PolarHBondContact O-N 3.23Å
408	L	96.8	Very high	95.8	Very high	93 Å²	93	48.4 Å²	48.4	49%	0.487	25%	0.253	S	S	.	.	H	α-helix	trans	-68.5	-42.3	176	-179.2	59.4	0	0	0	111.2	V404 S405 H406 V410 A411 I412	V404-L408 HydrophobicContact CG1-CB 4.03Å; V404-L408 HydrophobicContact CG1-CD2 4Å; V404-L408 HydrophobicContact CG1-CG 3.89Å; S405-L408 PolarHBondContact O-N 2.65Å; S405-L408 VanDerWaalsContact O-N 3.16Å; S405-L408 VanDerWaalsContact OG-CB 3.25Å; S405-L408 WeakPolarHBondContact OG-CB 3.48Å; H406-L408 VanDerWaalsContact C-N 3.32Å; H406-L408 PolarHBondContact O-N 3.25Å; L408-V410 VanDerWaalsContact C-N 3.32Å; L408-V410 PolarHBondContact O-N 3.24Å; L408-A411 PolarHBondContact O-N 3.27Å; L408-I412 HydrophobicContact CD1-CD1 4.04Å; L408-I412 HydrophobicContact CD1-CG1 4.16Å; L408-I412 HydrophobicContact CG-CD1 3.81Å; L408-I412 HydrophobicContact CG-CG1 4.38Å; L408-I412 WeakPolarHBondContact O-CB 3.44Å; L408-I412 VanDerWaalsContact O-CG1 3.26Å; L408-I412 WeakPolarHBondContact O-CG1 3.24Å; L408-I412 PolarHBondContact O-N 3.27Å
409	A	97.7	Very high	95.9	Very high	0 Å²	0	53 Å²	53	0%	0	28%	0.275	C	S	.	.	H	α-helix	trans	-60.9	-41.7	175.8	0	0	0	0	0	111.6	V396 M399 V404 S405 H406 A413	V396-A409 HydrophobicContact CG1-CB 4.04Å; M399-A409 HydrophobicContact CB-CB 3.9Å; M399-A409 HydrophobicContact CE-CB 4.05Å; M399-A409 WeakPolarHBondContact CE-O 3.29Å; M399-A409 HydrophobicContact SD-CB 4.44Å; V404-A409 HydrophobicContact CB-CB 4.38Å; V404-A409 HydrophobicContact CG1-CB 3.87Å; S405-A409 WeakPolarHBondContact O-CB 3.28Å; S405-A409 PolarHBondContact O-N 2.87Å; H406-A409 PolarHBondContact O-N 2.96Å; A409-A413 WeakPolarHBondContact O-CB 3.41Å; A409-A413 PolarHBondContact O-N 3.14Å
410	V	97.2	Very high	95.9	Very high	7 Å²	7	54.1 Å²	54.1	4%	0.042	28%	0.282	C	S	.	.	H	α-helix	trans	-60.8	-49.3	173	171.7	0	0	0	0	111	L210 V396 H406 L408 I412 A413 L414	L210-V410 HydrophobicContact CB-CG1 4.3Å; L210-V410 HydrophobicContact CD2-CG1 4.16Å; L210-V410 HydrophobicContact CD2-CG2 4.18Å; L210-V410 HydrophobicContact CG-CG1 4.16Å; L210-V410 HydrophobicContact CG-CG2 3.87Å; V396-V410 HydrophobicContact CG1-CG2 3.89Å; V396-V410 HydrophobicContact CG2-CG2 3.89Å; H406-V410 VanDerWaalsContact O-CG2 3.32Å; H406-V410 WeakPolarHBondContact O-CG2 3.27Å; H406-V410 PolarHBondContact O-N 3.4Å; L408-V410 VanDerWaalsContact C-N 3.32Å; L408-V410 PolarHBondContact O-N 3.24Å; V410-I412 PolarHBondContact O-N 2.85Å; V410-A413 PolarHBondContact O-N 3.31Å; V410-L414 HydrophobicContact CG1-CD1 3.53Å; V410-L414 HydrophobicContact CG1-CG 4.36Å; V410-L414 WeakPolarHBondContact O-CB 3.3Å; V410-L414 VanDerWaalsContact O-CG 3.26Å; V410-L414 WeakPolarHBondContact O-CG 3.19Å; V410-L414 PolarHBondContact O-N 3.34Å
411	A	97.1	Very high	96.1	Very high	39 Å²	39	50.1 Å²	50.1	32%	0.322	26%	0.264	S	S	.	.	H	α-helix	trans	-60.5	-45.6	179	0	0	0	0	0	112.1	R407 L408 I415	R407-A411 WeakPolarHBondContact O-CB 3.37Å; R407-A411 PolarHBondContact O-N 3.23Å; L408-A411 PolarHBondContact O-N 3.27Å; A411-I415 HydrophobicContact CB-CD1 4.43Å; A411-I415 VanDerWaalsContact O-CB 3.24Å; A411-I415 WeakPolarHBondContact O-CB 3.44Å; A411-I415 WeakPolarHBondContact O-CD1 3.23Å; A411-I415 WeakPolarHBondContact O-CG1 3.22Å; A411-I415 PolarHBondContact O-N 3Å
412	I	97.8	Very high	96.3	Very high	75 Å²	75	50.5 Å²	50.5	39%	0.385	27%	0.269	S	S	.	.	H	α-helix	trans	-59.7	-50.9	177.2	-69.3	166.6	0	0	0	110.5	M399 V404 L408 V410 L414 A416	M399-I412 HydrophobicContact CE-CG2 4.43Å; M399-I412 HydrophobicContact SD-CB 4.3Å; M399-I412 HydrophobicContact SD-CG2 3.93Å; V404-I412 HydrophobicContact CG1-CD1 4.24Å; L408-I412 HydrophobicContact CD1-CD1 4.04Å; L408-I412 HydrophobicContact CD1-CG1 4.16Å; L408-I412 HydrophobicContact CG-CD1 3.81Å; L408-I412 HydrophobicContact CG-CG1 4.38Å; L408-I412 WeakPolarHBondContact O-CB 3.44Å; L408-I412 VanDerWaalsContact O-CG1 3.26Å; L408-I412 WeakPolarHBondContact O-CG1 3.24Å; L408-I412 PolarHBondContact O-N 3.27Å; V410-I412 PolarHBondContact O-N 2.85Å; I412-L414 PolarHBondContact O-N 3.28Å; I412-A416 WeakPolarHBondContact O-CB 3.42Å; I412-A416 PolarHBondContact O-N 2.83Å
413	A	97.6	Very high	96.5	Very high	7 Å²	7	50.7 Å²	50.7	6%	0.058	27%	0.272	C	S	.	.	H	α-helix	trans	-59.4	-46.6	-177.6	0	0	0	0	0	111.7	T392 V396 M399 A409 V410 S417	T392-A413 HydrophobicContact CG2-CB 3.77Å; V396-A413 HydrophobicContact CG2-CB 4.16Å; M399-A413 HydrophobicContact CE-CB 3.94Å; A409-A413 WeakPolarHBondContact O-CB 3.41Å; A409-A413 PolarHBondContact O-N 3.14Å; V410-A413 PolarHBondContact O-N 3.31Å; A413-S417 WeakPolarHBondContact O-CB 3.43Å; A413-S417 PolarHBondContact O-N 2.82Å
414	L	96.6	Very high	96.6	Very high	17 Å²	17	46.7 Å²	46.7	9%	0.089	25%	0.251	C	S	.	.	H	α-helix	trans	-74	-41.7	-176.4	-66.1	170.9	0	0	0	112.9	V203 T392 V410 I412 A416 S417 A418	V203-L414 HydrophobicContact CG1-CB 3.69Å; V203-L414 HydrophobicContact CG1-CD2 3.86Å; V203-L414 HydrophobicContact CG1-CG 4.29Å; V203-L414 WeakPolarHBondContact CG1-O 3.18Å; T392-L414 HydrophobicContact CG2-CD2 3.92Å; T392-L414 HydrophobicContact CG2-CG 4.34Å; V410-L414 HydrophobicContact CG1-CD1 3.53Å; V410-L414 HydrophobicContact CG1-CG 4.36Å; V410-L414 WeakPolarHBondContact O-CB 3.3Å; V410-L414 VanDerWaalsContact O-CG 3.26Å; V410-L414 WeakPolarHBondContact O-CG 3.19Å; V410-L414 PolarHBondContact O-N 3.34Å; I412-L414 PolarHBondContact O-N 3.28Å; L414-A416 VanDerWaalsContact C-N 3.35Å; L414-S417 PolarHBondContact O-N 2.78Å; L414-A418 WeakPolarHBondContact O-CB 3.26Å; L414-A418 PolarHBondContact O-N 3.36Å
415	I	97.3	Very high	96.7	Very high	103 Å²	103	45.1 Å²	45.1	53%	0.528	24%	0.242	S	C	.	.	H	α-helix	trans	-65.1	-43.1	176.9	-68.5	168.2	0	0	0	109.8	A411 A418 I419	A411-I415 HydrophobicContact CB-CD1 4.43Å; A411-I415 VanDerWaalsContact O-CB 3.24Å; A411-I415 WeakPolarHBondContact O-CB 3.44Å; A411-I415 WeakPolarHBondContact O-CD1 3.23Å; A411-I415 WeakPolarHBondContact O-CG1 3.22Å; A411-I415 PolarHBondContact O-N 3Å; I415-A418 PolarHBondContact O-N 3.35Å; I415-I419 HydrophobicContact CG2-CD1 3.64Å; I415-I419 HydrophobicContact CG2-CG1 4.41Å; I415-I419 WeakPolarHBondContact O-CB 3.15Å; I415-I419 VanDerWaalsContact O-CG1 3.29Å; I415-I419 WeakPolarHBondContact O-CG1 3.46Å; I415-I419 PolarHBondContact O-N 2.81Å
416	A	97.8	Very high	96.6	Very high	26 Å²	26	46.8 Å²	46.8	22%	0.215	24%	0.244	C	C	.	.	H	α-helix	trans	-65.8	-44.2	177.2	0	0	0	0	0	111.6	F149 I412 L414 A418 I419 I420	F149-A416 HydrophobicContact CE2-CB 3.87Å; F149-A416 HydrophobicContact CZ-CB 3.74Å; I412-A416 WeakPolarHBondContact O-CB 3.42Å; I412-A416 PolarHBondContact O-N 2.83Å; L414-A416 VanDerWaalsContact C-N 3.35Å; A416-A418 PolarHBondContact O-N 2.81Å; A416-I419 PolarHBondContact O-N 3.15Å; A416-I420 VanDerWaalsContact O-CB 3.27Å; A416-I420 WeakPolarHBondContact O-CB 3.28Å; A416-I420 VanDerWaalsContact O-CG1 3.3Å; A416-I420 WeakPolarHBondContact O-CG1 3.31Å; A416-I420 PolarHBondContact O-N 2.97Å
417	S	97.1	Very high	96.5	Very high	0 Å²	0	49.8 Å²	49.8	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-56.9	-45.7	173	154.6	0	0	0	0	112.1	S152 A413 L414 G421	S152-S417 WeakPolarHBondContact O-CB 3.27Å; S152-S417 PolarHBondContact O-OG 2.95Å; A413-S417 WeakPolarHBondContact O-CB 3.43Å; A413-S417 PolarHBondContact O-N 2.82Å; L414-S417 PolarHBondContact O-N 2.78Å; S417-G421 WeakPolarHBondContact O-CA 3.35Å; S417-G421 PolarHBondContact O-N 3.16Å
418	A	97.3	Very high	96.2	Very high	4 Å²	4	41.6 Å²	41.6	3%	0.033	23%	0.226	C	C	.	.	H	α-helix	trans	-63.2	-49.2	178.6	0	0	0	0	0	111.9	Q199 F200 V203 L414 I415 A416 V422	Q199-A418 PolarHBondContact NE2-O 3.4Å; F200-A418 HydrophobicContact CD1-CB 4.16Å; F200-A418 HydrophobicContact CE1-CB 3.81Å; F200-A418 HydrophobicContact CE2-CB 4.44Å; F200-A418 HydrophobicContact CZ-CB 3.98Å; V203-A418 HydrophobicContact CG1-CB 4.28Å; V203-A418 HydrophobicContact CG2-CB 4.29Å; L414-A418 WeakPolarHBondContact O-CB 3.26Å; L414-A418 PolarHBondContact O-N 3.36Å; I415-A418 PolarHBondContact O-N 3.35Å; A416-A418 PolarHBondContact O-N 2.81Å; A418-V422 WeakPolarHBondContact O-CG2 3.25Å; A418-V422 PolarHBondContact O-N 2.81Å
419	I	97.9	Very high	95.9	Very high	104 Å²	104	40.8 Å²	40.8	53%	0.533	22%	0.222	S	C	.	.	H	α-helix	trans	-68.9	-48.5	-176.7	-66.6	171.2	0	0	0	111.3	I415 A416 G421 V422	I415-I419 HydrophobicContact CG2-CD1 3.64Å; I415-I419 HydrophobicContact CG2-CG1 4.41Å; I415-I419 WeakPolarHBondContact O-CB 3.15Å; I415-I419 VanDerWaalsContact O-CG1 3.29Å; I415-I419 WeakPolarHBondContact O-CG1 3.46Å; I415-I419 PolarHBondContact O-N 2.81Å; A416-I419 PolarHBondContact O-N 3.15Å; I419-G421 PolarHBondContact O-N 2.98Å; I419-V422 WeakPolarHBondContact O-CB 3.44Å; I419-V422 WeakPolarHBondContact O-CG2 3.32Å; I419-V422 PolarHBondContact O-N 3.29Å
420	I	97.6	Very high	95.7	Very high	67 Å²	67	42.4 Å²	42.4	34%	0.344	23%	0.229	S	C	.	.	H	α-helix	trans	-71.3	-23	-178.9	-62.1	178.2	0	0	0	111.2	F149 F150 C153 A416 P423	F149-I420 HydrophobicContact CE1-CD1 3.84Å; F149-I420 HydrophobicContact CZ-CD1 3.78Å; F150-I420 HydrophobicContact CD1-CG2 4.4Å; F150-I420 HydrophobicContact CE1-CG2 4.23Å; C153-I420 HydrophobicContact CB-CB 4.38Å; C153-I420 HydrophobicContact CB-CG2 4.14Å; A416-I420 VanDerWaalsContact O-CB 3.27Å; A416-I420 WeakPolarHBondContact O-CB 3.28Å; A416-I420 VanDerWaalsContact O-CG1 3.3Å; A416-I420 WeakPolarHBondContact O-CG1 3.31Å; A416-I420 PolarHBondContact O-N 2.97Å; I420-P423 WeakPolarHBondContact O-CD 3.48Å
421	G	97.6	Very high	95.5	Very high	0 Å²	0	42.5 Å²	42.5	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-76.4	-15.3	172.6	0	0	0	0	0	114.9	C153 S417 I419 S424 A425	C153-G421 WeakPolarHBondContact O-CA 3.21Å; S417-G421 WeakPolarHBondContact O-CA 3.35Å; S417-G421 PolarHBondContact O-N 3.16Å; I419-G421 PolarHBondContact O-N 2.98Å; G421-S424 WeakPolarHBondContact O-CA 3.35Å; G421-S424 WeakPolarHBondContact O-CB 3.49Å; G421-S424 PolarHBondContact O-N 3.09Å; G421-A425 PolarHBondContact O-N 2.62Å
422	V	97.5	Very high	95.1	Very high	40 Å²	40	42.2 Å²	42.2	24%	0.242	22%	0.224	C	C	.	.	H	α-helix	trans	-56.4	-45.8	-178.4	175	0	0	0	0	112.7	V196 F200 A418 I419 S424 A425 I426	V196-V422 HydrophobicContact CG2-CG1 4.49Å; F200-V422 HydrophobicContact CE2-CG2 3.92Å; F200-V422 HydrophobicContact CZ-CG2 4.41Å; A418-V422 WeakPolarHBondContact O-CG2 3.25Å; A418-V422 PolarHBondContact O-N 2.81Å; I419-V422 WeakPolarHBondContact O-CB 3.44Å; I419-V422 WeakPolarHBondContact O-CG2 3.32Å; I419-V422 PolarHBondContact O-N 3.29Å; V422-S424 VanDerWaalsContact C-N 3.27Å; V422-S424 PolarHBondContact O-N 2.91Å; V422-A425 WeakPolarHBondContact O-CA 3.27Å; V422-A425 WeakPolarHBondContact O-CB 3.4Å; V422-A425 PolarHBondContact O-N 3.12Å; V422-I426 HydrophobicContact CG1-CD1 4.47Å; V422-I426 HydrophobicContact CG1-CG2 4.27Å; V422-I426 WeakPolarHBondContact O-CG1 3.41Å; V422-I426 PolarHBondContact O-N 3.19Å
423	P	95.6	Very high	94.9	Very high	49 Å²	49	38.7 Å²	38.7	32%	0.318	21%	0.206	S	C	.	.	H	α-helix	trans	-55.3	-38.9	174.1	-27.5	36.9	0	0	0	113.5	I420 A425 I426 Y427 F430	I420-P423 WeakPolarHBondContact O-CD 3.48Å; P423-A425 VanDerWaalsContact C-N 3.3Å; P423-A425 PolarHBondContact O-N 3.24Å; P423-I426 PolarHBondContact O-N 3.14Å; P423-Y427 PolarHBondContact O-N 3.08Å; P423-F430 HydrophobicContact CB-CD1 3.61Å; P423-F430 HydrophobicContact CB-CD2 4.23Å; P423-F430 HydrophobicContact CB-CE1 3.61Å; P423-F430 HydrophobicContact CB-CE2 4.24Å; P423-F430 HydrophobicContact CB-CG 3.94Å; P423-F430 HydrophobicContact CB-CZ 3.94Å; P423-F430 HydrophobicContact CG-CE1 4.44Å
424	S	94.8	Very high	94.8	Very high	3 Å²	3	38.9 Å²	38.9	2%	0.021	21%	0.205	C	C	.	.	H	α-helix	trans	-67.4	-30	174.2	-57.6	0	0	0	0	112.6	G421 V422 F430	G421-S424 WeakPolarHBondContact O-CA 3.35Å; G421-S424 WeakPolarHBondContact O-CB 3.49Å; G421-S424 PolarHBondContact O-N 3.09Å; V422-S424 VanDerWaalsContact C-N 3.27Å; V422-S424 PolarHBondContact O-N 2.91Å; S424-F430 VanDerWaalsContact OG-CD1 3.3Å; S424-F430 WeakPolarHBondContact OG-CD1 3.41Å; S424-F430 WeakPolarHBondContact OG-CE1 3.48Å
425	A	94.9	Very high	94.5	Very high	5 Å²	5	39.8 Å²	39.8	4%	0.041	21%	0.21	C	C	.	.	H	α-helix	trans	-75.5	-35.1	177.9	0	0	0	0	0	113.3	V157 P195 V196 Q199 G421 V422 P423	V157-A425 HydrophobicContact CG1-CB 4.12Å; V157-A425 HydrophobicContact CG2-CB 3.9Å; P195-A425 HydrophobicContact CB-CB 4.15Å; P195-A425 VanDerWaalsContact CB-O 3.26Å; P195-A425 WeakPolarHBondContact CB-O 3.46Å; V196-A425 HydrophobicContact CG2-CB 3.97Å; Q199-A425 VanDerWaalsContact OE1-CB 3.29Å; G421-A425 PolarHBondContact O-N 2.62Å; V422-A425 WeakPolarHBondContact O-CA 3.27Å; V422-A425 WeakPolarHBondContact O-CB 3.4Å; V422-A425 PolarHBondContact O-N 3.12Å; P423-A425 VanDerWaalsContact C-N 3.3Å; P423-A425 PolarHBondContact O-N 3.24Å
426	I	94.1	Very high	94.2	Very high	107 Å²	107	37.8 Å²	37.8	55%	0.549	20%	0.201	S	C	.	.	H	α-helix	trans	-94.8	-18.9	-177.1	67.3	-178.5	0	0	0	113.4	V196 V422 P423	V196-I426 HydrophobicContact CG2-CG2 3.56Å; V422-I426 HydrophobicContact CG1-CD1 4.47Å; V422-I426 HydrophobicContact CG1-CG2 4.27Å; V422-I426 WeakPolarHBondContact O-CG1 3.41Å; V422-I426 PolarHBondContact O-N 3.19Å; P423-I426 PolarHBondContact O-N 3.14Å
427	Y	91.5	Very high	94	Very high	100 Å²	100	36.5 Å²	36.5	39%	0.392	19%	0.19	S	C	.	.			trans	-141.3	112.7	-176.4	-173	-130.1	0	0	0	112.2	P423 D429 F430 L431 W515	P423-Y427 PolarHBondContact O-N 3.08Å; Y427-D429 HydrophobicContact CD1-CB 4.38Å; Y427-D429 HydrophobicContact CE1-CB 3.69Å; Y427-D429 HydrophobicContact CE2-CB 4.16Å; Y427-D429 VanDerWaalsContact CZ-OD2 3.23Å; Y427-D429 PolarHBondContact O-N 3.4Å; Y427-D429 PolarHBondContact OH-OD2 2.97Å; Y427-F430 HydrophobicContact CD1-CB 3.81Å; Y427-F430 WeakPolarHBondContact O-CB 3.15Å; Y427-F430 PolarHBondContact O-N 3.37Å; Y427-L431 PolarHBondContact O-N 3.48Å; Y427-W515 AromaticContact CE1-CD1 3.67Å; Y427-W515 HydrophobicContact CE1-CD2 4.46Å; Y427-W515 AromaticContact CE1-CE2 3.94Å; Y427-W515 HydrophobicContact CE1-CG 4.31Å; Y427-W515 AromaticContact CE1-NE1 3.45Å
428	L	89.6	Confident	93.9	Very high	27 Å²	27	36.7 Å²	36.7	14%	0.141	19%	0.191	C	C	.	.	H	α-helix	trans	-72.2	-29.1	-168.6	-169	63.8	0	0	0	114.2	W161 P348 F430 L431 T432	W161-L428 HydrophobicContact CH2-CD1 3.53Å; W161-L428 HydrophobicContact CZ2-CD1 3.84Å; P348-L428 HydrophobicContact CB-CD2 3.13Å; L428-F430 VanDerWaalsContact C-N 3.27Å; L428-F430 PolarHBondContact O-N 3.32Å; L428-L431 HydrophobicContact CD1-CB 4.35Å; L428-L431 HydrophobicContact CD1-CD1 4.27Å; L428-L431 HydrophobicContact CD1-CD2 4.37Å; L428-L431 WeakPolarHBondContact O-CB 3.43Å; L428-L431 PolarHBondContact O-N 3.29Å; L428-T432 PolarHBondContact O-N 3.01Å; L428-T432 PolarHBondContact O-OG1 3.39Å
429	D	90	Very high	93.6	Very high	76 Å²	76	37.7 Å²	37.7	41%	0.406	20%	0.201	S	C	.	.	H	α-helix	trans	-67.6	-33.7	174.6	-62.2	-30.5	0	0	0	110.8	Y427 T432 N433 W515	Y427-D429 HydrophobicContact CD1-CB 4.38Å; Y427-D429 HydrophobicContact CE1-CB 3.69Å; Y427-D429 HydrophobicContact CE2-CB 4.16Å; Y427-D429 VanDerWaalsContact CZ-OD2 3.23Å; Y427-D429 PolarHBondContact O-N 3.4Å; Y427-D429 PolarHBondContact OH-OD2 2.97Å; D429-T432 PolarHBondContact O-N 2.89Å; D429-N433 WeakPolarHBondContact O-CB 3.08Å; D429-N433 PolarHBondContact O-N 2.88Å; D429-W515 HydrophobicContact CB-CB 4.22Å; D429-W515 HydrophobicContact CB-CG 4.38Å
430	F	92.6	Very high	93.2	Very high	35 Å²	35	36.1 Å²	36.1	15%	0.154	19%	0.189	C	C	.	.	H	α-helix	trans	-66.1	-42.6	171.8	-174.5	-84.8	0	0	0	111.2	P423 S424 Y427 L428 T432 N433 Q434 W515	P423-F430 HydrophobicContact CB-CD1 3.61Å; P423-F430 HydrophobicContact CB-CD2 4.23Å; P423-F430 HydrophobicContact CB-CE1 3.61Å; P423-F430 HydrophobicContact CB-CE2 4.24Å; P423-F430 HydrophobicContact CB-CG 3.94Å; P423-F430 HydrophobicContact CB-CZ 3.94Å; P423-F430 HydrophobicContact CG-CE1 4.44Å; S424-F430 VanDerWaalsContact OG-CD1 3.3Å; S424-F430 WeakPolarHBondContact OG-CD1 3.41Å; S424-F430 WeakPolarHBondContact OG-CE1 3.48Å; Y427-F430 HydrophobicContact CD1-CB 3.81Å; Y427-F430 WeakPolarHBondContact O-CB 3.15Å; Y427-F430 PolarHBondContact O-N 3.37Å; L428-F430 VanDerWaalsContact C-N 3.27Å; L428-F430 PolarHBondContact O-N 3.32Å; F430-T432 VanDerWaalsContact C-N 3.31Å; F430-T432 PolarHBondContact O-N 3.4Å; F430-N433 WeakPolarHBondContact O-CB 3.15Å; F430-N433 PolarHBondContact O-N 3.43Å; F430-Q434 HydrophobicContact CD1-CG 3.81Å; F430-Q434 HydrophobicContact CE1-CG 3.38Å; F430-Q434 HydrophobicContact CZ-CG 3.83Å; F430-Q434 VanDerWaalsContact O-CG 3.3Å; F430-Q434 WeakPolarHBondContact O-CG 3.3Å; F430-Q434 PolarHBondContact O-N 2.88Å; F430-W515 AromaticContact CD2-CE3 3.89Å; F430-W515 HydrophobicContact CD2-CE3 3.89Å; F430-W515 AromaticContact CD2-CH2 3.76Å; F430-W515 HydrophobicContact CD2-CH2 3.76Å; F430-W515 AromaticContact CD2-CZ3 3.36Å; F430-W515 HydrophobicContact CD2-CZ3 3.36Å; F430-W515 HydrophobicContact CE2-CH2 4.23Å; F430-W515 AromaticContact CE2-CZ3 3.77Å; F430-W515 HydrophobicContact CE2-CZ3 3.77Å
431	L	92.7	Very high	93.1	Very high	8 Å²	8	32.9 Å²	32.9	4%	0.042	17%	0.173	C	C	.	.	H	α-helix	trans	-58	-45.7	172.7	-178.1	156.9	0	0	0	111.5	V157 V158 W161 Y427 L428 N433 Q434 D435	V157-L431 HydrophobicContact CB-CD1 4.19Å; V157-L431 HydrophobicContact CG1-CD1 3.85Å; V158-L431 HydrophobicContact CG2-CD1 4.42Å; W161-L431 HydrophobicContact CH2-CD1 3.71Å; W161-L431 HydrophobicContact CZ2-CD1 3.74Å; Y427-L431 PolarHBondContact O-N 3.48Å; L428-L431 HydrophobicContact CD1-CB 4.35Å; L428-L431 HydrophobicContact CD1-CD1 4.27Å; L428-L431 HydrophobicContact CD1-CD2 4.37Å; L428-L431 WeakPolarHBondContact O-CB 3.43Å; L428-L431 PolarHBondContact O-N 3.29Å; L431-N433 PolarHBondContact O-N 3.42Å; L431-Q434 PolarHBondContact O-N 3.43Å; L431-D435 PolarHBondContact O-N 3.47Å
432	T	90.2	Very high	92.9	Very high	34 Å²	34	33.7 Å²	33.7	21%	0.209	18%	0.177	C	C	.	.	H	α-helix	trans	-63.6	-41.7	179.9	-57	0	0	0	0	111.7	L428 D429 F430 N436	L428-T432 PolarHBondContact O-N 3.01Å; L428-T432 PolarHBondContact O-OG1 3.39Å; D429-T432 PolarHBondContact O-N 2.89Å; F430-T432 VanDerWaalsContact C-N 3.31Å; F430-T432 PolarHBondContact O-N 3.4Å; T432-N436 WeakPolarHBondContact O-CB 3.43Å; T432-N436 VanDerWaalsContact O-CG 3.28Å; T432-N436 PolarHBondContact O-N 3.23Å; T432-N436 PolarHBondContact O-ND2 3.04Å
433	N	93.5	Very high	92.7	Very high	1 Å²	1	32.8 Å²	32.8	1%	0.005	17%	0.171	C	C	.	.	H	α-helix	trans	-55.8	-55.7	171.5	165	-103.9	0	0	0	111	D429 F430 L431 D435 N436 T437 W515 E524	D429-N433 WeakPolarHBondContact O-CB 3.08Å; D429-N433 PolarHBondContact O-N 2.88Å; F430-N433 WeakPolarHBondContact O-CB 3.15Å; F430-N433 PolarHBondContact O-N 3.43Å; L431-N433 PolarHBondContact O-N 3.42Å; N433-D435 PolarHBondContact O-N 2.96Å; N433-N436 PolarHBondContact O-N 3.4Å; N433-T437 WeakPolarHBondContact O-CB 3.45Å; N433-T437 PolarHBondContact O-N 3.37Å; N433-T437 PolarHBondContact O-OG1 2.95Å; N433-T437 VanDerWaalsContact O-OG1 3.08Å; N433-W515 HydrophobicContact CB-CB 4.25Å; N433-W515 WeakPolarHBondContact CB-O 3.29Å; N433-W515 VanDerWaalsContact CG-O 3.3Å; N433-W515 PolarHBondContact ND2-O 3.22Å; N433-E524 PolarHBondContact ND2-OE1 3.33Å; N433-E524 PolarHBondContact OD1-OE1 3.45Å
434	Q	94.9	Very high	92.7	Very high	10 Å²	10	32.4 Å²	32.4	5%	0.047	17%	0.166	C	C	.	.	H	α-helix	trans	-62.3	-40.2	-177.6	-65.2	-60.7	-69.4	0	0	112.4	Y154 F430 L431 N436 W438 E524	Y154-Q434 HydrophobicContact CD1-CB 4.03Å; Y154-Q434 HydrophobicContact CG-CB 4.48Å; F430-Q434 HydrophobicContact CD1-CG 3.81Å; F430-Q434 HydrophobicContact CE1-CG 3.38Å; F430-Q434 HydrophobicContact CZ-CG 3.83Å; F430-Q434 VanDerWaalsContact O-CG 3.3Å; F430-Q434 WeakPolarHBondContact O-CG 3.3Å; F430-Q434 PolarHBondContact O-N 2.88Å; L431-Q434 PolarHBondContact O-N 3.43Å; Q434-N436 PolarHBondContact O-N 3.21Å; Q434-W438 WeakPolarHBondContact O-CB 3.37Å; Q434-W438 PolarHBondContact O-N 2.52Å; Q434-W438 VanDerWaalsContact O-N 3.09Å; Q434-E524 PolarHBondContact NE2-OE2 2.89Å
435	D	91.3	Very high	92.8	Very high	36 Å²	36	32.2 Å²	32.2	19%	0.193	17%	0.165	C	C	.	.	H	α-helix	trans	-60.1	-45.8	175.1	-172.7	43.3	0	0	0	111.4	Y154 L431 N433 G439	Y154-D435 HydrophobicContact CE2-CB 3.91Å; Y154-D435 WeakPolarHBondContact CE2-OD1 3.48Å; Y154-D435 VanDerWaalsContact CZ-OD1 3.27Å; Y154-D435 PolarHBondContact OH-OD1 3.12Å; L431-D435 PolarHBondContact O-N 3.47Å; N433-D435 PolarHBondContact O-N 2.96Å; D435-G439 WeakPolarHBondContact O-CA 3.42Å; D435-G439 PolarHBondContact O-N 3.39Å
436	N	89.9	Confident	92.9	Very high	61 Å²	61	32.1 Å²	32.1	33%	0.326	16%	0.164	S	C	.	.	H	α-helix	trans	-68	-54.4	178.8	-71.7	-22.7	0	0	0	111.8	T432 N433 Q434 W438 G439 Y440	T432-N436 WeakPolarHBondContact O-CB 3.43Å; T432-N436 VanDerWaalsContact O-CG 3.28Å; T432-N436 PolarHBondContact O-N 3.23Å; T432-N436 PolarHBondContact O-ND2 3.04Å; N433-N436 PolarHBondContact O-N 3.4Å; Q434-N436 PolarHBondContact O-N 3.21Å; N436-W438 PolarHBondContact O-N 3.33Å; N436-G439 PolarHBondContact O-N 3.11Å; N436-Y440 HydrophobicContact CB-CE2 4.33Å; N436-Y440 WeakPolarHBondContact O-CD2 3.43Å; N436-Y440 PolarHBondContact O-N 3.26Å
437	T	94.1	Very high	93	Very high	0 Å²	0	30.1 Å²	30.1	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-56.4	-47.9	-175.5	-66.9	0	0	0	0	111.9	N433 G441 T521 E524 W525	N433-T437 WeakPolarHBondContact O-CB 3.45Å; N433-T437 PolarHBondContact O-N 3.37Å; N433-T437 PolarHBondContact O-OG1 2.95Å; N433-T437 VanDerWaalsContact O-OG1 3.08Å; T437-G441 PolarHBondContact O-N 3.01Å; T437-T521 HydrophobicContact CG2-CG2 4Å; T437-T521 PolarHBondContact OG1-OG1 2.84Å; T437-E524 HydrophobicContact CG2-CB 3.98Å; T437-W525 WeakPolarHBondContact O-CZ2 3.39Å; T437-W525 PolarHBondContact O-NE1 3.26Å
438	W	94.1	Very high	93.4	Very high	4 Å²	4	26 Å²	26	2%	0.015	14%	0.136	C	C	.	.	H	α-helix	trans	-84.6	-26.2	-178.4	-58	111.6	0	0	0	112.3	V147 F150 Q434 N436 G441 L442 A528	V147-W438 HydrophobicContact CB-CE3 4.26Å; V147-W438 HydrophobicContact CG1-CB 4.29Å; V147-W438 HydrophobicContact CG1-CE3 4.38Å; V147-W438 VanDerWaalsContact CG1-O 3.3Å; V147-W438 WeakPolarHBondContact CG1-O 3.34Å; V147-W438 HydrophobicContact CG2-CE3 3.96Å; V147-W438 HydrophobicContact CG2-CZ3 4.23Å; F150-W438 HydrophobicContact CB-CD2 3.64Å; F150-W438 VanDerWaalsContact CB-CE2 3.47Å; F150-W438 HydrophobicContact CB-CE3 4.48Å; F150-W438 HydrophobicContact CB-CG 3.58Å; F150-W438 HydrophobicContact CB-CZ2 4.19Å; F150-W438 VanDerWaalsContact CB-NE1 3.27Å; F150-W438 HydrophobicContact CD1-CZ2 4.17Å; F150-W438 AromaticContact CD1-NE1 3.87Å; F150-W438 AromaticContact CD2-CD2 3.91Å; F150-W438 HydrophobicContact CD2-CD2 3.91Å; F150-W438 AromaticContact CD2-CE2 3.38Å; F150-W438 HydrophobicContact CD2-CE3 4.18Å; F150-W438 AromaticContact CD2-CH2 3.48Å; F150-W438 HydrophobicContact CD2-CH2 3.48Å; F150-W438 VanDerWaalsContact CD2-CH2 3.48Å; F150-W438 AromaticContact CD2-CZ2 3.15Å; F150-W438 HydrophobicContact CD2-CZ2 3.15Å; F150-W438 AromaticContact CD2-CZ3 3.98Å; F150-W438 HydrophobicContact CD2-CZ3 3.98Å; F150-W438 AromaticContact CD2-NE1 3.96Å; F150-W438 HydrophobicContact CE1-CZ2 4.36Å; F150-W438 AromaticContact CE2-CH2 3.59Å; F150-W438 HydrophobicContact CE2-CH2 3.59Å; F150-W438 AromaticContact CE2-CZ2 3.38Å; F150-W438 HydrophobicContact CE2-CZ2 3.38Å; F150-W438 HydrophobicContact CE2-CZ3 4.43Å; F150-W438 AromaticContact CG-CD2 3.99Å; F150-W438 HydrophobicContact CG-CD2 3.99Å; F150-W438 AromaticContact CG-CE2 3.38Å; F150-W438 HydrophobicContact CG-CG 4.4Å; F150-W438 HydrophobicContact CG-CH2 4.34Å; F150-W438 AromaticContact CG-CZ2 3.6Å; F150-W438 HydrophobicContact CG-CZ2 3.6Å; F150-W438 AromaticContact CG-NE1 3.45Å; F150-W438 HydrophobicContact CZ-CZ2 4Å; Q434-W438 WeakPolarHBondContact O-CB 3.37Å; Q434-W438 PolarHBondContact O-N 2.52Å; Q434-W438 VanDerWaalsContact O-N 3.09Å; N436-W438 PolarHBondContact O-N 3.33Å; W438-G441 WeakPolarHBondContact O-CA 3.16Å; W438-G441 PolarHBondContact O-N 3.31Å; W438-G441 VanDerWaalsContact O-N 3.1Å; W438-L442 PolarHBondContact O-N 3.33Å; W438-L442 VanDerWaalsContact O-N 3.11Å; W438-A528 HydrophobicContact CH2-CB 3.95Å
439	G	90.6	Very high	93.8	Very high	24 Å²	24	24.7 Å²	24.7	25%	0.247	13%	0.13	C	C	.	.	H	α-helix	trans	-58	-46	168.8	0	0	0	0	0	112.8	D435 N436 G441 L442	D435-G439 WeakPolarHBondContact O-CA 3.42Å; D435-G439 PolarHBondContact O-N 3.39Å; N436-G439 PolarHBondContact O-N 3.11Å; G439-G441 VanDerWaalsContact C-N 3.32Å; G439-L442 WeakPolarHBondContact O-CB 3.41Å; G439-L442 PolarHBondContact O-N 3.21Å
440	Y	91.2	Very high	94.2	Very high	71 Å²	71	21.1 Å²	21.1	28%	0.278	11%	0.11	S	C	.	.	H	α-helix	trans	-70.1	-29.9	172.5	-66.8	-62.6	0	0	0	112.4	N436 L442 V443 W499	N436-Y440 HydrophobicContact CB-CE2 4.33Å; N436-Y440 WeakPolarHBondContact O-CD2 3.43Å; N436-Y440 PolarHBondContact O-N 3.26Å; Y440-L442 PolarHBondContact O-N 2.78Å; Y440-V443 WeakPolarHBondContact O-CB 3Å; Y440-V443 PolarHBondContact O-N 3.48Å; Y440-W499 HydrophobicContact CD1-CB 4.48Å; Y440-W499 AromaticContact CD1-CD2 3.83Å; Y440-W499 HydrophobicContact CD1-CD2 3.83Å; Y440-W499 HydrophobicContact CD1-CE3 4.13Å; Y440-W499 AromaticContact CD1-CG 3.97Å; Y440-W499 HydrophobicContact CD1-CG 3.97Å; Y440-W499 AromaticContact CD2-CD2 3.88Å; Y440-W499 HydrophobicContact CD2-CD2 3.88Å; Y440-W499 AromaticContact CD2-CE2 3.43Å; Y440-W499 VanDerWaalsContact CD2-CE2 3.43Å; Y440-W499 HydrophobicContact CD2-CE3 4.32Å; Y440-W499 HydrophobicContact CD2-CG 4.48Å; Y440-W499 AromaticContact CD2-CH2 3.99Å; Y440-W499 HydrophobicContact CD2-CH2 3.99Å; Y440-W499 AromaticContact CD2-CZ2 3.49Å; Y440-W499 HydrophobicContact CD2-CZ2 3.49Å; Y440-W499 VanDerWaalsContact CD2-CZ2 3.49Å; Y440-W499 HydrophobicContact CD2-CZ3 4.38Å; Y440-W499 AromaticContact CD2-NE1 3.84Å; Y440-W499 HydrophobicContact CE1-CB 3.96Å; Y440-W499 AromaticContact CE1-CD1 3.61Å; Y440-W499 AromaticContact CE1-CD2 3.77Å; Y440-W499 HydrophobicContact CE1-CD2 3.77Å; Y440-W499 AromaticContact CE1-CG 3.45Å; Y440-W499 HydrophobicContact CE1-CG 3.45Å; Y440-W499 VanDerWaalsContact CE1-CG 3.45Å; Y440-W499 AromaticContact CE1-NE1 3.96Å; Y440-W499 AromaticContact CE2-CD1 3.67Å; Y440-W499 AromaticContact CE2-CD2 3.86Å; Y440-W499 HydrophobicContact CE2-CD2 3.86Å; Y440-W499 AromaticContact CE2-CE2 3.27Å; Y440-W499 HydrophobicContact CE2-CG 4.07Å; Y440-W499 AromaticContact CE2-CZ2 3.7Å; Y440-W499 HydrophobicContact CE2-CZ2 3.7Å; Y440-W499 AromaticContact CE2-NE1 3.14Å; Y440-W499 AromaticContact CG-CD2 3.9Å; Y440-W499 HydrophobicContact CG-CD2 3.9Å; Y440-W499 AromaticContact CG-CE2 3.96Å; Y440-W499 HydrophobicContact CG-CE3 4.05Å; Y440-W499 HydrophobicContact CG-CG 4.46Å; Y440-W499 HydrophobicContact CG-CH2 4.3Å; Y440-W499 HydrophobicContact CG-CZ2 4.16Å; Y440-W499 HydrophobicContact CG-CZ3 4.25Å; Y440-W499 AromaticContact CZ-CD1 3.17Å; Y440-W499 AromaticContact CZ-CD2 3.8Å; Y440-W499 AromaticContact CZ-CE2 3.61Å; Y440-W499 AromaticContact CZ-CG 3.52Å; Y440-W499 AromaticContact CZ-NE1 3.21Å; Y440-W499 PolarHBondContact OH-NE1 3.05Å
441	G	94.2	Very high	94.5	Very high	0 Å²	0	22 Å²	22	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-59.9	-29	173.2	0	0	0	0	0	113.4	W143 T437 W438 G439 V443 I444 S445	W143-G441 PolarHBondContact NE1-O 3.09Å; T437-G441 PolarHBondContact O-N 3.01Å; W438-G441 WeakPolarHBondContact O-CA 3.16Å; W438-G441 PolarHBondContact O-N 3.31Å; W438-G441 VanDerWaalsContact O-N 3.1Å; G439-G441 VanDerWaalsContact C-N 3.32Å; G441-V443 VanDerWaalsContact C-N 3.32Å; G441-V443 PolarHBondContact O-N 3.25Å; G441-I444 WeakPolarHBondContact O-CB 3.4Å; G441-I444 PolarHBondContact O-N 3.1Å; G441-S445 PolarHBondContact O-N 3.05Å; G441-S445 VanDerWaalsContact O-N 3.09Å; G441-S445 PolarHBondContact O-OG 2.99Å
442	L	93.7	Very high	94.7	Very high	17 Å²	17	21.7 Å²	21.7	9%	0.089	12%	0.115	C	C	.	.	H	α-helix	trans	-66.9	-30.7	173.9	-67.4	174.3	0	0	0	113.1	V147 V148 L151 M281 W438 G439 Y440 I444 S445 G446	V147-L442 HydrophobicContact CG1-CD2 3.57Å; V147-L442 HydrophobicContact CG1-CG 3.82Å; V148-L442 HydrophobicContact CG2-CD2 4.17Å; L151-L442 HydrophobicContact CD1-CD1 4.48Å; M281-L442 HydrophobicContact CB-CD2 4.4Å; M281-L442 HydrophobicContact CE-CD1 3.58Å; M281-L442 HydrophobicContact CG-CD1 4.17Å; M281-L442 HydrophobicContact CG-CD2 3.66Å; W438-L442 PolarHBondContact O-N 3.33Å; W438-L442 VanDerWaalsContact O-N 3.11Å; G439-L442 WeakPolarHBondContact O-CB 3.41Å; G439-L442 PolarHBondContact O-N 3.21Å; Y440-L442 PolarHBondContact O-N 2.78Å; L442-I444 VanDerWaalsContact C-N 3.29Å; L442-I444 PolarHBondContact O-N 3.19Å; L442-S445 WeakPolarHBondContact O-CB 3.31Å; L442-S445 PolarHBondContact O-N 2.82Å; L442-G446 PolarHBondContact O-N 3.38Å
443	V	93.7	Very high	95.1	Very high	20 Å²	20	20.1 Å²	20.1	12%	0.121	11%	0.105	C	C	.	.	H	α-helix	trans	-65.2	-38.9	175	-175.4	0	0	0	0	110.1	W106 Y440 G441 G446 F447 L495 L496	W106-V443 HydrophobicContact CH2-CG1 4.14Å; W106-V443 HydrophobicContact CZ2-CG1 4.27Å; Y440-V443 WeakPolarHBondContact O-CB 3Å; Y440-V443 PolarHBondContact O-N 3.48Å; G441-V443 VanDerWaalsContact C-N 3.32Å; G441-V443 PolarHBondContact O-N 3.25Å; V443-G446 PolarHBondContact O-N 2.9Å; V443-F447 PolarHBondContact O-N 3.48Å; V443-L495 HydrophobicContact CG1-CB 4.49Å; V443-L496 HydrophobicContact CB-CD1 4.34Å; V443-L496 HydrophobicContact CB-CD2 4.1Å; V443-L496 HydrophobicContact CB-CG 4.14Å; V443-L496 HydrophobicContact CG1-CD1 4.02Å; V443-L496 HydrophobicContact CG1-CD2 4.31Å; V443-L496 HydrophobicContact CG1-CG 3.8Å
444	I	95.7	Very high	95.4	Very high	41 Å²	41	23.1 Å²	23.1	21%	0.21	12%	0.121	C	C	.	.	H	α-helix	trans	-62.9	-43.9	172.4	-61	173.2	0	0	0	110.1	W143 G441 L442 G446 F447 L448 L496 W525	W143-I444 HydrophobicContact CH2-CD1 4.24Å; W143-I444 HydrophobicContact CZ2-CB 4.04Å; W143-I444 HydrophobicContact CZ2-CD1 3.71Å; W143-I444 HydrophobicContact CZ2-CG1 4.43Å; W143-I444 HydrophobicContact CZ2-CG2 4.09Å; G441-I444 WeakPolarHBondContact O-CB 3.4Å; G441-I444 PolarHBondContact O-N 3.1Å; L442-I444 VanDerWaalsContact C-N 3.29Å; L442-I444 PolarHBondContact O-N 3.19Å; I444-G446 PolarHBondContact O-N 3.48Å; I444-F447 WeakPolarHBondContact O-CB 3.5Å; I444-F447 PolarHBondContact O-N 2.87Å; I444-L448 HydrophobicContact CG2-CD1 4.41Å; I444-L448 HydrophobicContact CG2-CG 4.43Å; I444-L448 WeakPolarHBondContact O-CG 3.39Å; I444-L448 PolarHBondContact O-N 3.14Å; I444-L496 HydrophobicContact CG1-CD1 3.7Å; I444-W525 HydrophobicContact CD1-CD2 4.4Å; I444-W525 HydrophobicContact CD1-CE3 3.97Å; I444-W525 HydrophobicContact CD1-CH2 3.88Å; I444-W525 HydrophobicContact CD1-CZ2 4.3Å; I444-W525 HydrophobicContact CD1-CZ3 3.71Å
445	S	96.8	Very high	95.5	Very high	0 Å²	0	26.7 Å²	26.7	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-59.2	-44.1	176.5	-57.8	0	0	0	0	112.5	W143 G280 G441 L442 F447 L448 F449	W143-S445 PolarHBondContact NE1-OG 3.43Å; G280-S445 WeakPolarHBondContact O-CB 3.18Å; G441-S445 PolarHBondContact O-N 3.05Å; G441-S445 VanDerWaalsContact O-N 3.09Å; G441-S445 PolarHBondContact O-OG 2.99Å; L442-S445 WeakPolarHBondContact O-CB 3.31Å; L442-S445 PolarHBondContact O-N 2.82Å; S445-F447 PolarHBondContact O-N 2.82Å; S445-L448 PolarHBondContact O-N 3.17Å; S445-F449 WeakPolarHBondContact O-CD2 3.33Å; S445-F449 PolarHBondContact O-N 3.43Å; S445-F449 VanDerWaalsContact O-N 3.16Å
446	G	96.1	Very high	95.8	Very high	2 Å²	2	25.4 Å²	25.4	2%	0.021	14%	0.135	C	C	.	.	H	α-helix	trans	-58.4	-46	173.3	0	0	0	0	0	112.6	L442 V443 I444 L448 F449 C450	L442-G446 PolarHBondContact O-N 3.38Å; V443-G446 PolarHBondContact O-N 2.9Å; I444-G446 PolarHBondContact O-N 3.48Å; G446-L448 VanDerWaalsContact C-N 3.31Å; G446-L448 PolarHBondContact O-N 2.96Å; G446-F449 PolarHBondContact O-N 2.99Å; G446-C450 PolarHBondContact O-N 3.23Å; G446-C450 PolarHBondContact O-SG 3.18Å; G446-C450 VanDerWaalsContact O-SG 3.38Å
447	F	97.3	Very high	96.2	Very high	66 Å²	66	23.7 Å²	23.7	29%	0.289	13%	0.132	S	C	.	.	H	α-helix	trans	-59.2	-40.7	175.2	177.9	-92.2	0	0	0	112.6	V443 I444 S445 F449 C450 L451 P489 V493	V443-F447 PolarHBondContact O-N 3.48Å; I444-F447 WeakPolarHBondContact O-CB 3.5Å; I444-F447 PolarHBondContact O-N 2.87Å; S445-F447 PolarHBondContact O-N 2.82Å; F447-F449 VanDerWaalsContact C-N 3.34Å; F447-F449 PolarHBondContact O-N 2.75Å; F447-C450 WeakPolarHBondContact O-CB 3.06Å; F447-C450 PolarHBondContact O-N 3.23Å; F447-C450 VanDerWaalsContact O-N 3.13Å; F447-L451 PolarHBondContact O-N 3.15Å; F447-P489 HydrophobicContact CD2-CB 4.19Å; F447-P489 HydrophobicContact CE2-CB 4.02Å; F447-V493 HydrophobicContact CD2-CG2 4.39Å; F447-V493 HydrophobicContact CE2-CG2 4.08Å
448	L	98.4	Very high	96.4	Very high	13 Å²	13	24.8 Å²	24.8	7%	0.068	14%	0.139	C	C	.	.	H	α-helix	trans	-65	-34.9	178.8	-71.6	-178.3	0	0	0	112.8	F129 L140 W143 M144 I444 S445 G446 C450 L451 L452	F129-L448 HydrophobicContact CE1-CB 4.28Å; F129-L448 HydrophobicContact CZ-CB 4.44Å; L140-L448 HydrophobicContact CD2-CD1 4.45Å; L140-L448 HydrophobicContact CD2-CD2 3.86Å; L140-L448 WeakPolarHBondContact O-CD1 3.31Å; W143-L448 HydrophobicContact CB-CD1 4.38Å; W143-L448 HydrophobicContact CG-CD1 4.25Å; M144-L448 HydrophobicContact CE-CB 3.41Å; M144-L448 VanDerWaalsContact CE-CB 3.41Å; M144-L448 HydrophobicContact CE-CD1 4.04Å; M144-L448 HydrophobicContact CE-CG 4.38Å; I444-L448 HydrophobicContact CG2-CD1 4.41Å; I444-L448 HydrophobicContact CG2-CG 4.43Å; I444-L448 WeakPolarHBondContact O-CG 3.39Å; I444-L448 PolarHBondContact O-N 3.14Å; S445-L448 PolarHBondContact O-N 3.17Å; G446-L448 VanDerWaalsContact C-N 3.31Å; G446-L448 PolarHBondContact O-N 2.96Å; L448-C450 VanDerWaalsContact C-N 3.35Å; L448-L451 HydrophobicContact CD2-CD2 4.19Å; L448-L451 PolarHBondContact O-N 3.45Å; L448-L452 PolarHBondContact O-N 2.93Å
449	F	98.5	Very high	96.6	Very high	0 Å²	0	27.8 Å²	27.8	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-62.4	-42.4	170	-79.7	-66.2	0	0	0	111.8	I110 V113 E114 L117 V125 F129 M144 S445 G446 F447 L452 V453	I110-F449 HydrophobicContact CG2-CB 4.47Å; I110-F449 HydrophobicContact CG2-CD2 4.3Å; V113-F449 HydrophobicContact CG1-CB 4.17Å; V113-F449 HydrophobicContact CG1-CD1 3.9Å; V113-F449 HydrophobicContact CG1-CG 4.44Å; E114-F449 HydrophobicContact CG-CD1 4.4Å; E114-F449 HydrophobicContact CG-CD2 4.34Å; E114-F449 HydrophobicContact CG-CE1 4.01Å; E114-F449 HydrophobicContact CG-CE2 3.94Å; E114-F449 HydrophobicContact CG-CZ 3.77Å; L117-F449 HydrophobicContact CD2-CD1 4.23Å; L117-F449 HydrophobicContact CD2-CE1 3.79Å; V125-F449 HydrophobicContact CG1-CE1 4.41Å; V125-F449 HydrophobicContact CG1-CZ 4.14Å; F129-F449 HydrophobicContact CE2-CD1 4.06Å; F129-F449 AromaticContact CE2-CE1 3.92Å; F129-F449 HydrophobicContact CE2-CE1 3.92Å; F129-F449 HydrophobicContact CZ-CD1 4.11Å; F129-F449 HydrophobicContact CZ-CE1 4.39Å; M144-F449 HydrophobicContact CE-CD2 4.21Å; M144-F449 HydrophobicContact CE-CE2 4.16Å; M144-F449 HydrophobicContact CE-CG 4.48Å; M144-F449 HydrophobicContact CE-CZ 4.37Å; M144-F449 HydrophobicContact SD-CD2 3.94Å; M144-F449 HydrophobicContact SD-CE1 4.24Å; M144-F449 HydrophobicContact SD-CE2 3.33Å; M144-F449 WeakPolarHBondContact SD-CE2 3.4Å; M144-F449 HydrophobicContact SD-CZ 3.5Å; M144-F449 VanDerWaalsContact SD-CZ 3.5Å; S445-F449 WeakPolarHBondContact O-CD2 3.33Å; S445-F449 PolarHBondContact O-N 3.43Å; S445-F449 VanDerWaalsContact O-N 3.16Å; G446-F449 PolarHBondContact O-N 2.99Å; F447-F449 VanDerWaalsContact C-N 3.34Å; F447-F449 PolarHBondContact O-N 2.75Å; F449-L452 WeakPolarHBondContact O-CB 3.45Å; F449-L452 PolarHBondContact O-N 2.67Å; F449-V453 PolarHBondContact O-N 3.42Å
450	C	98.5	Very high	96.9	Very high	0 Å²	0	32.1 Å²	32.1	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-63.2	-43.3	174.8	-55.8	0	0	0	0	111.6	G446 F447 L448 L452 V453 I454 V488 P489	G446-C450 PolarHBondContact O-N 3.23Å; G446-C450 PolarHBondContact O-SG 3.18Å; G446-C450 VanDerWaalsContact O-SG 3.38Å; F447-C450 WeakPolarHBondContact O-CB 3.06Å; F447-C450 PolarHBondContact O-N 3.23Å; F447-C450 VanDerWaalsContact O-N 3.13Å; L448-C450 VanDerWaalsContact C-N 3.35Å; C450-L452 VanDerWaalsContact C-N 3.29Å; C450-L452 PolarHBondContact O-N 2.91Å; C450-V453 PolarHBondContact O-N 2.91Å; C450-V453 VanDerWaalsContact O-N 3.11Å; C450-I454 HydrophobicContact CB-CD1 4.49Å; C450-I454 VanDerWaalsContact O-CG1 3.27Å; C450-I454 WeakPolarHBondContact O-CG1 3.48Å; C450-I454 PolarHBondContact O-N 2.83Å; C450-V488 VanDerWaalsContact SG-CG1 3.5Å; C450-P489 HydrophobicContact CB-CG 3.75Å
451	L	98.4	Very high	97.2	Very high	55 Å²	55	28.8 Å²	28.8	29%	0.288	15%	0.151	S	C	.	.	H	α-helix	trans	-58	-41.2	178.4	-177.1	64.7	0	0	0	111.8	F133 F447 L448 V453 I454 V455	F133-L451 HydrophobicContact CZ-CG 4.42Å; F447-L451 PolarHBondContact O-N 3.15Å; L448-L451 HydrophobicContact CD2-CD2 4.19Å; L448-L451 PolarHBondContact O-N 3.45Å; L451-V453 PolarHBondContact O-N 2.89Å; L451-I454 PolarHBondContact O-N 3.41Å; L451-V455 HydrophobicContact CD1-CG2 4.05Å; L451-V455 HydrophobicContact CG-CG2 4.4Å; L451-V455 WeakPolarHBondContact O-CB 3.49Å; L451-V455 WeakPolarHBondContact O-CG2 3.36Å; L451-V455 PolarHBondContact O-N 2.83Å
452	L	98.6	Very high	97.4	Very high	1 Å²	1	30.4 Å²	30.4	1%	0.005	16%	0.157	C	C	.	.	H	α-helix	trans	-56.6	-48.6	174.1	-175	153.5	0	0	0	111.7	L117 F129 F132 F133 L448 F449 C450 Y456 Y461	L117-L452 HydrophobicContact CD1-CD1 4.15Å; L117-L452 HydrophobicContact CD1-CD2 4.33Å; L117-L452 HydrophobicContact CD2-CD1 4.21Å; F129-L452 HydrophobicContact CD1-CD1 3.94Å; F129-L452 HydrophobicContact CD2-CD1 3.8Å; F129-L452 HydrophobicContact CE1-CB 4.08Å; F129-L452 HydrophobicContact CE1-CD1 3.84Å; F129-L452 HydrophobicContact CE2-CD1 3.71Å; F129-L452 HydrophobicContact CG-CD1 3.92Å; F129-L452 HydrophobicContact CZ-CB 4.17Å; F129-L452 HydrophobicContact CZ-CD1 3.71Å; F132-L452 HydrophobicContact CB-CD1 4.27Å; F132-L452 HydrophobicContact CB-CG 4.17Å; F132-L452 HydrophobicContact CD1-CD2 3.77Å; F132-L452 HydrophobicContact CD1-CG 4.06Å; F132-L452 HydrophobicContact CD2-CD1 3.89Å; F132-L452 HydrophobicContact CD2-CD2 4.17Å; F132-L452 HydrophobicContact CD2-CG 4.21Å; F132-L452 HydrophobicContact CE1-CD2 3.73Å; F132-L452 HydrophobicContact CE1-CG 4.5Å; F132-L452 HydrophobicContact CE2-CD1 4.4Å; F132-L452 HydrophobicContact CE2-CD2 4.17Å; F132-L452 HydrophobicContact CG-CD1 4Å; F132-L452 HydrophobicContact CG-CD2 3.98Å; F132-L452 HydrophobicContact CG-CG 3.87Å; F132-L452 HydrophobicContact CZ-CD2 3.92Å; F133-L452 HydrophobicContact CE2-CB 3.85Å; F133-L452 HydrophobicContact CE2-CD1 4.17Å; F133-L452 HydrophobicContact CE2-CG 3.98Å; F133-L452 HydrophobicContact CZ-CB 4.1Å; L448-L452 PolarHBondContact O-N 2.93Å; F449-L452 WeakPolarHBondContact O-CB 3.45Å; F449-L452 PolarHBondContact O-N 2.67Å; C450-L452 VanDerWaalsContact C-N 3.29Å; C450-L452 PolarHBondContact O-N 2.91Å; L452-Y456 WeakPolarHBondContact O-CB 3.34Å; L452-Y456 PolarHBondContact O-N 2.79Å; L452-Y456 VanDerWaalsContact O-N 3.09Å; L452-Y461 HydrophobicContact CD2-CD2 4.27Å; L452-Y461 HydrophobicContact CD2-CE2 3.68Å
453	V	98.6	Very high	97.5	Very high	0 Å²	0	35.3 Å²	35.3	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-64.7	-41.7	178.8	175.8	0	0	0	0	111.6	V113 F449 C450 L451 G457 P458 Y461 W480 I484	V113-V453 HydrophobicContact CB-CG2 4.33Å; V113-V453 HydrophobicContact CG1-CG2 3.75Å; V113-V453 HydrophobicContact CG2-CG2 3.55Å; F449-V453 PolarHBondContact O-N 3.42Å; C450-V453 PolarHBondContact O-N 2.91Å; C450-V453 VanDerWaalsContact O-N 3.11Å; L451-V453 PolarHBondContact O-N 2.89Å; V453-G457 CarbonylContact O-C 3.33Å; V453-G457 PolarHBondContact O-N 2.94Å; V453-P458 HydrophobicContact CG1-CB 3.97Å; V453-P458 HydrophobicContact CG1-CG 4.24Å; V453-P458 WeakPolarHBondContact O-CD 3.46Å; V453-Y461 HydrophobicContact CG1-CD1 4.49Å; V453-Y461 HydrophobicContact CG1-CG 4.14Å; V453-Y461 HydrophobicContact CG2-CD1 4.22Å; V453-Y461 HydrophobicContact CG2-CD2 4Å; V453-Y461 HydrophobicContact CG2-CE1 4.26Å; V453-Y461 HydrophobicContact CG2-CE2 4.02Å; V453-Y461 HydrophobicContact CG2-CG 4.1Å; V453-W480 HydrophobicContact CG1-CH2 3.8Å; V453-W480 HydrophobicContact CG1-CZ3 4.23Å; V453-W480 HydrophobicContact CG2-CH2 4.29Å; V453-I484 HydrophobicContact CB-CG1 4.38Å; V453-I484 HydrophobicContact CG1-CG1 4.28Å; V453-I484 HydrophobicContact CG1-CG2 3.89Å; V453-I484 HydrophobicContact CG2-CG1 4.34Å
454	I	98.5	Very high	97.5	Very high	65 Å²	65	35.5 Å²	35.5	33%	0.333	18%	0.176	S	C	.	.	H	α-helix	trans	-62.9	-48.9	-180	-69.7	163.8	0	0	0	110.7	C450 L451 G457 A485 P489	C450-I454 HydrophobicContact CB-CD1 4.49Å; C450-I454 VanDerWaalsContact O-CG1 3.27Å; C450-I454 WeakPolarHBondContact O-CG1 3.48Å; C450-I454 PolarHBondContact O-N 2.83Å; L451-I454 PolarHBondContact O-N 3.41Å; I454-G457 PolarHBondContact O-N 2.87Å; I454-A485 HydrophobicContact CG1-CB 4.2Å; I454-P489 HydrophobicContact CD1-CG 3.82Å
455	V	97.6	Very high	97.5	Very high	84 Å²	84	33.6 Å²	33.6	51%	0.509	17%	0.166	S	C	.	.	H	α-helix	trans	-68.7	-36.9	-177.5	171.6	0	0	0	0	111.9	F133 L451 G457	F133-V455 HydrophobicContact CD1-CG1 4.29Å; F133-V455 HydrophobicContact CE1-CB 3.81Å; F133-V455 HydrophobicContact CE1-CG1 3.77Å; F133-V455 HydrophobicContact CE1-CG2 3.93Å; F133-V455 HydrophobicContact CZ-CB 4.32Å; F133-V455 HydrophobicContact CZ-CG2 4.5Å; L451-V455 HydrophobicContact CD1-CG2 4.05Å; L451-V455 HydrophobicContact CG-CG2 4.4Å; L451-V455 WeakPolarHBondContact O-CB 3.49Å; L451-V455 WeakPolarHBondContact O-CG2 3.36Å; L451-V455 PolarHBondContact O-N 2.83Å; V455-G457 VanDerWaalsContact C-N 3.26Å; V455-G457 PolarHBondContact O-N 3.23Å
456	Y	97.7	Very high	97.5	Very high	10 Å²	10	33.8 Å²	33.8	4%	0.039	17%	0.167	C	C	.	.	H	α-helix	trans	-70.5	-24.3	175.2	-175.2	-105.9	0	0	0	113.3	F132 L452 R460 Y461 L465 P557 Y558	F132-Y456 AromaticContact CD1-CD2 3.75Å; F132-Y456 HydrophobicContact CD1-CD2 3.75Å; F132-Y456 AromaticContact CD1-CG 3.95Å; F132-Y456 HydrophobicContact CD1-CG 3.95Å; F132-Y456 HydrophobicContact CE1-CD1 4.26Å; F132-Y456 AromaticContact CE1-CD2 3.69Å; F132-Y456 HydrophobicContact CE1-CD2 3.69Å; F132-Y456 HydrophobicContact CE1-CE2 4.22Å; F132-Y456 AromaticContact CE1-CG 3.71Å; F132-Y456 HydrophobicContact CE1-CG 3.71Å; L452-Y456 WeakPolarHBondContact O-CB 3.34Å; L452-Y456 PolarHBondContact O-N 2.79Å; L452-Y456 VanDerWaalsContact O-N 3.09Å; Y456-R460 HydrophobicContact CD1-CB 4.43Å; Y456-R460 HydrophobicContact CD1-CG 4.35Å; Y456-R460 HydrophobicContact CE1-CB 4.13Å; Y456-R460 HydrophobicContact CE1-CG 3.64Å; Y456-R460 PolarHBondContact OH-NE 2.98Å; Y456-R460 VanDerWaalsContact OH-NE 3.1Å; Y456-Y461 AromaticContact CD1-CD2 3.93Å; Y456-Y461 HydrophobicContact CD1-CD2 3.93Å; Y456-Y461 HydrophobicContact CD1-CG 4.35Å; Y456-L465 HydrophobicContact CD1-CD1 4.43Å; Y456-L465 HydrophobicContact CE1-CD1 3.64Å; Y456-P557 HydrophobicContact CD2-CB 4.4Å; Y456-P557 HydrophobicContact CE2-CB 3.8Å; Y456-P557 WeakPolarHBondContact CE2-O 3.43Å; Y456-P557 PolarHBondContact OH-O 2.92Å; Y456-Y558 HydrophobicContact CD2-CD1 4.44Å; Y456-Y558 AromaticContact CD2-CE1 3.73Å; Y456-Y558 HydrophobicContact CD2-CE1 3.73Å; Y456-Y558 AromaticContact CD2-CZ 3.77Å; Y456-Y558 HydrophobicContact CE2-CD1 4Å; Y456-Y558 AromaticContact CE2-CE1 3.74Å; Y456-Y558 HydrophobicContact CE2-CE1 3.74Å
457	G	98.1	Very high	97.4	Very high	24 Å²	24	34.8 Å²	34.8	25%	0.247	17%	0.172	C	C	.	.			trans	102.1	106.1	-173	0	0	0	0	0	110.6	V453 I454 V455 N459 R460 Y461	V453-G457 CarbonylContact O-C 3.33Å; V453-G457 PolarHBondContact O-N 2.94Å; I454-G457 PolarHBondContact O-N 2.87Å; V455-G457 VanDerWaalsContact C-N 3.26Å; V455-G457 PolarHBondContact O-N 3.23Å; G457-N459 PolarHBondContact O-N 3.17Å; G457-R460 CarbonylContact O-C 3.38Å; G457-R460 WeakPolarHBondContact O-CA 3.4Å; G457-R460 WeakPolarHBondContact O-CB 3.07Å; G457-R460 PolarHBondContact O-N 2.97Å; G457-Y461 PolarHBondContact O-N 3.46Å
458	P	98.3	Very high	97.2	Very high	24 Å²	24	36.4 Å²	36.4	16%	0.156	18%	0.18	C	C	.	.	H	α-helix	trans	-57.4	-42	-170	-30.4	35.6	0	0	0	115.2	V453 Y461 R462 V481 A485	V453-P458 HydrophobicContact CG1-CB 3.97Å; V453-P458 HydrophobicContact CG1-CG 4.24Å; V453-P458 WeakPolarHBondContact O-CD 3.46Å; P458-Y461 WeakPolarHBondContact O-CB 3.29Å; P458-Y461 PolarHBondContact O-N 3.21Å; P458-R462 PolarHBondContact O-N 3.32Å; P458-V481 HydrophobicContact CB-CG1 3.77Å; P458-V481 HydrophobicContact CB-CG2 4.49Å; P458-A485 HydrophobicContact CB-CB 4.1Å; P458-A485 HydrophobicContact CG-CB 3.6Å
459	N	97.8	Very high	97	Very high	67 Å²	67	36.6 Å²	36.6	36%	0.358	18%	0.18	S	C	.	.	H	α-helix	trans	-72.8	-31.7	177.5	-171.3	45.5	0	0	0	112.1	G457 R462 R463 V481	G457-N459 PolarHBondContact O-N 3.17Å; N459-R462 PolarHBondContact OD1-NE 3.15Å; N459-R462 PolarHBondContact OD1-NH2 2.99Å; N459-R462 VanDerWaalsContact OD1-NH2 3.07Å; N459-R463 WeakPolarHBondContact O-CB 3.45Å; N459-R463 WeakPolarHBondContact O-CG 3.3Å; N459-R463 PolarHBondContact O-N 2.76Å; N459-R463 VanDerWaalsContact O-N 3.09Å; N459-V481 HydrophobicContact CB-CG2 4.38Å
460	R	96.6	Very high	96.6	Very high	115 Å²	115	37.3 Å²	37.3	43%	0.434	19%	0.188	S	C	.	.	H	α-helix	trans	-65.4	-44.9	171.8	-174.2	-173.5	174.6	160.9	1.7	110.1	Y456 G457 R463 V464	Y456-R460 HydrophobicContact CD1-CB 4.43Å; Y456-R460 HydrophobicContact CD1-CG 4.35Å; Y456-R460 HydrophobicContact CE1-CB 4.13Å; Y456-R460 HydrophobicContact CE1-CG 3.64Å; Y456-R460 PolarHBondContact OH-NE 2.98Å; Y456-R460 VanDerWaalsContact OH-NE 3.1Å; G457-R460 CarbonylContact O-C 3.38Å; G457-R460 WeakPolarHBondContact O-CA 3.4Å; G457-R460 WeakPolarHBondContact O-CB 3.07Å; G457-R460 PolarHBondContact O-N 2.97Å; R460-R463 PolarHBondContact O-N 3.24Å; R460-V464 HydrophobicContact CG-CG2 4.04Å; R460-V464 WeakPolarHBondContact O-CB 3.28Å; R460-V464 WeakPolarHBondContact O-CG2 3.35Å; R460-V464 PolarHBondContact O-N 3Å
461	Y	98.2	Very high	96.2	Very high	0 Å²	0	41.6 Å²	41.6	0%	0	21%	0.21	C	C	.	.	H	α-helix	trans	-55	-54.3	175	-167.2	-81	0	0	0	111.1	V113 S116 L117 F132 L452 V453 Y456 G457 P458 R463 L465 I466 W480	V113-Y461 PolarHBondContact O-OH 2.81Å; S116-Y461 VanDerWaalsContact OG-CE1 3.26Å; S116-Y461 WeakPolarHBondContact OG-CE1 3.46Å; S116-Y461 PolarHBondContact OG-OH 3.03Å; L117-Y461 PolarHBondContact N-OH 3.27Å; F132-Y461 HydrophobicContact CE1-CD2 4.34Å; F132-Y461 HydrophobicContact CE1-CE2 4.25Å; F132-Y461 HydrophobicContact CZ-CE2 4.17Å; L452-Y461 HydrophobicContact CD2-CD2 4.27Å; L452-Y461 HydrophobicContact CD2-CE2 3.68Å; V453-Y461 HydrophobicContact CG1-CD1 4.49Å; V453-Y461 HydrophobicContact CG1-CG 4.14Å; V453-Y461 HydrophobicContact CG2-CD1 4.22Å; V453-Y461 HydrophobicContact CG2-CD2 4Å; V453-Y461 HydrophobicContact CG2-CE1 4.26Å; V453-Y461 HydrophobicContact CG2-CE2 4.02Å; V453-Y461 HydrophobicContact CG2-CG 4.1Å; Y456-Y461 AromaticContact CD1-CD2 3.93Å; Y456-Y461 HydrophobicContact CD1-CD2 3.93Å; Y456-Y461 HydrophobicContact CD1-CG 4.35Å; G457-Y461 PolarHBondContact O-N 3.46Å; P458-Y461 WeakPolarHBondContact O-CB 3.29Å; P458-Y461 PolarHBondContact O-N 3.21Å; Y461-R463 VanDerWaalsContact C-N 3.27Å; Y461-R463 PolarHBondContact O-N 3.31Å; Y461-L465 HydrophobicContact CD1-CB 4.45Å; Y461-L465 HydrophobicContact CD2-CD1 4.38Å; Y461-L465 HydrophobicContact CD2-CD2 4.11Å; Y461-L465 HydrophobicContact CE1-CB 4.28Å; Y461-L465 HydrophobicContact CE2-CD2 3.57Å; Y461-L465 HydrophobicContact CE2-CG 4.48Å; Y461-L465 WeakPolarHBondContact O-CB 3.02Å; Y461-L465 PolarHBondContact O-N 3.38Å; Y461-I466 HydrophobicContact CD1-CD1 4.06Å; Y461-I466 HydrophobicContact CD1-CG1 4.38Å; Y461-I466 HydrophobicContact CE1-CD1 3.97Å; Y461-I466 HydrophobicContact CE1-CG1 4.2Å; Y461-W480 AromaticContact CD1-CH2 3.65Å; Y461-W480 HydrophobicContact CD1-CH2 3.65Å; Y461-W480 HydrophobicContact CD1-CZ3 4.22Å; Y461-W480 HydrophobicContact CE1-CH2 4.14Å; Y461-W480 HydrophobicContact CG-CH2 4.49Å
462	R	97.9	Very high	95.7	Very high	35 Å²	35	43.9 Å²	43.9	13%	0.132	22%	0.222	C	C	.	.	I	π-helix	trans	-54.6	-42.1	178.8	-174.1	-172.5	69.7	84.3	5.9	112.6	P458 N459 I466 N467 L476 S477 W480	P458-R462 PolarHBondContact O-N 3.32Å; N459-R462 PolarHBondContact OD1-NE 3.15Å; N459-R462 PolarHBondContact OD1-NH2 2.99Å; N459-R462 VanDerWaalsContact OD1-NH2 3.07Å; R462-I466 WeakPolarHBondContact O-CB 3.26Å; R462-N467 PolarHBondContact NH1-ND2 3.24Å; R462-N467 PolarHBondContact O-N 3.14Å; R462-N467 VanDerWaalsContact O-N 3.15Å; R462-L476 WeakPolarHBondContact CD-O 3.36Å; R462-L476 HydrophobicContact CG-CB 4.24Å; R462-L476 HydrophobicContact CG-CD2 4.12Å; R462-L476 HydrophobicContact CG-CG 4.22Å; R462-L476 PolarHBondContact NH1-O 3Å; R462-S477 WeakPolarHBondContact CD-O 3.48Å; R462-W480 HydrophobicContact CB-CE3 4.07Å; R462-W480 HydrophobicContact CB-CZ3 3.93Å; R462-W480 HydrophobicContact CG-CE3 4.25Å
463	R	95.6	Very high	95.4	Very high	120 Å²	120	45.4 Å²	45.4	45%	0.453	23%	0.23	S	C	.	.	I	π-helix	trans	-73.1	-60.2	-179.8	-74.8	-176.8	58.6	-162.1	-7.2	111.5	N459 R460 Y461 N467 E468	N459-R463 WeakPolarHBondContact O-CB 3.45Å; N459-R463 WeakPolarHBondContact O-CG 3.3Å; N459-R463 PolarHBondContact O-N 2.76Å; N459-R463 VanDerWaalsContact O-N 3.09Å; R460-R463 PolarHBondContact O-N 3.24Å; Y461-R463 VanDerWaalsContact C-N 3.27Å; Y461-R463 PolarHBondContact O-N 3.31Å; R463-N467 PolarHBondContact O-N 3.18Å; R463-E468 IonicContact CZ-OE1 3.34Å; R463-E468 IonicContact NE-OE1 3.03Å; R463-E468 PolarHBondContact NE-OE1 3.4Å; R463-E468 IonicContact NH2-OE1 2.8Å; R463-E468 PolarHBondContact NH2-OE1 3.49Å; R463-E468 VanDerWaalsContact O-CB 3.28Å; R463-E468 WeakPolarHBondContact O-CB 3.48Å; R463-E468 WeakPolarHBondContact O-CG 3.22Å; R463-E468 PolarHBondContact O-N 3.02Å
464	V	94.7	Very high	95.2	Very high	24 Å²	24	48.3 Å²	48.3	15%	0.145	25%	0.25	C	C	.	.	I	π-helix	trans	-72.1	-46.1	-167.8	177.9	0	0	0	0	112	F120 R460 F469 P560	F120-V464 HydrophobicContact CE2-CG1 4.47Å; F120-V464 HydrophobicContact CZ-CG1 4.46Å; R460-V464 HydrophobicContact CG-CG2 4.04Å; R460-V464 WeakPolarHBondContact O-CB 3.28Å; R460-V464 WeakPolarHBondContact O-CG2 3.35Å; R460-V464 PolarHBondContact O-N 3Å; V464-F469 WeakPolarHBondContact O-CB 3.34Å; V464-P560 HydrophobicContact CG1-CB 3.99Å; V464-P560 HydrophobicContact CG1-CG 4.02Å
465	L	95.1	Very high	95	Very high	0 Å²	0	52.3 Å²	52.3	0%	0	27%	0.267	C	S	.	.	I	π-helix	trans	-88.8	-21.2	-171.4	-81.3	82.1	0	0	0	114	F120 F132 Y456 Y461	F120-L465 HydrophobicContact CB-CD2 4.12Å; F120-L465 HydrophobicContact CB-CG 4.29Å; F120-L465 HydrophobicContact CD1-CD2 3.67Å; F120-L465 HydrophobicContact CD1-CG 3.77Å; F120-L465 HydrophobicContact CD2-CB 4.2Å; F120-L465 HydrophobicContact CD2-CD2 4.41Å; F120-L465 HydrophobicContact CD2-CG 3.75Å; F120-L465 HydrophobicContact CE1-CD1 4.35Å; F120-L465 HydrophobicContact CE1-CD2 4.15Å; F120-L465 HydrophobicContact CE1-CG 3.96Å; F120-L465 HydrophobicContact CE2-CD1 4.48Å; F120-L465 HydrophobicContact CE2-CG 3.93Å; F120-L465 HydrophobicContact CG-CB 4.33Å; F120-L465 HydrophobicContact CG-CD2 3.82Å; F120-L465 HydrophobicContact CG-CG 3.67Å; F120-L465 HydrophobicContact CZ-CD1 4.27Å; F120-L465 HydrophobicContact CZ-CG 4.03Å; F132-L465 HydrophobicContact CE1-CD2 4.4Å; F132-L465 HydrophobicContact CZ-CD2 3.64Å; Y456-L465 HydrophobicContact CD1-CD1 4.43Å; Y456-L465 HydrophobicContact CE1-CD1 3.64Å; Y461-L465 HydrophobicContact CD1-CB 4.45Å; Y461-L465 HydrophobicContact CD2-CD1 4.38Å; Y461-L465 HydrophobicContact CD2-CD2 4.11Å; Y461-L465 HydrophobicContact CE1-CB 4.28Å; Y461-L465 HydrophobicContact CE2-CD2 3.57Å; Y461-L465 HydrophobicContact CE2-CG 4.48Å; Y461-L465 WeakPolarHBondContact O-CB 3.02Å; Y461-L465 PolarHBondContact O-N 3.38Å
466	I	96.1	Very high	95	Very high	5 Å²	5	48.8 Å²	48.8	3%	0.026	25%	0.245	C	C	.	.	I	π-helix	trans	-111.3	-70.5	-172.7	-52.4	-178.9	0	0	0	109.6	I112 I297 V298 Y461 R462 G470 L476 W480	I112-I466 HydrophobicContact CG2-CD1 3.49Å; I112-I466 VanDerWaalsContact CG2-CD1 3.49Å; I297-I466 HydrophobicContact CD1-CG2 4.04Å; V298-I466 HydrophobicContact CG2-CG2 3.39Å; Y461-I466 HydrophobicContact CD1-CD1 4.06Å; Y461-I466 HydrophobicContact CD1-CG1 4.38Å; Y461-I466 HydrophobicContact CE1-CD1 3.97Å; Y461-I466 HydrophobicContact CE1-CG1 4.2Å; R462-I466 WeakPolarHBondContact O-CB 3.26Å; I466-G470 PolarHBondContact O-N 2.92Å; I466-G470 VanDerWaalsContact O-N 3.16Å; I466-L476 HydrophobicContact CD1-CD2 3.49Å; I466-L476 VanDerWaalsContact CD1-CD2 3.49Å; I466-L476 HydrophobicContact CG2-CB 3.97Å; I466-L476 HydrophobicContact CG2-CD2 4.23Å; I466-W480 HydrophobicContact CD1-CH2 4.32Å
467	N	95.4	Very high	94.9	Very high	22 Å²	22	51.1 Å²	51.1	12%	0.118	26%	0.263	C	S	.	.	I	π-helix	trans	-74.1	-47	-168.7	-70.6	-2.7	0	0	0	113.6	R462 R463 L476	R462-N467 PolarHBondContact NH1-ND2 3.24Å; R462-N467 PolarHBondContact O-N 3.14Å; R462-N467 VanDerWaalsContact O-N 3.15Å; R463-N467 PolarHBondContact O-N 3.18Å; N467-L476 PolarHBondContact ND2-O 3.34Å; N467-L476 WeakPolarHBondContact OD1-CB 3.35Å; N467-L476 PolarHBondContact OD1-N 3.43Å
468	E	93.2	Very high	94.9	Very high	101 Å²	101	54.7 Å²	54.7	47%	0.472	28%	0.275	S	S	.	.	T	Hydrogen-bonded Turn	trans	-80.4	-25.7	-176.8	-65.3	169.3	-172.8	0	0	111.5	R463	R463-E468 IonicContact CZ-OE1 3.34Å; R463-E468 IonicContact NE-OE1 3.03Å; R463-E468 PolarHBondContact NE-OE1 3.4Å; R463-E468 IonicContact NH2-OE1 2.8Å; R463-E468 PolarHBondContact NH2-OE1 3.49Å; R463-E468 VanDerWaalsContact O-CB 3.28Å; R463-E468 WeakPolarHBondContact O-CB 3.48Å; R463-E468 WeakPolarHBondContact O-CG 3.22Å; R463-E468 PolarHBondContact O-N 3.02Å
469	F	92.7	Very high	94.8	Very high	16 Å²	16	61.2 Å²	61.2	7%	0.07	30%	0.301	C	S	.	.	T	Hydrogen-bonded Turn	trans	-81.9	-38.2	179.2	-172	-111.7	0	0	0	113.5	R119 F120 R293 V464 C555	R119-F469 HydrophobicContact CG-CE1 4.27Å; F120-F469 HydrophobicContact CB-CD1 4.43Å; F120-F469 HydrophobicContact CB-CE1 4.34Å; F120-F469 HydrophobicContact CD2-CB 4.1Å; F120-F469 AromaticContact CD2-CD1 3.81Å; F120-F469 HydrophobicContact CD2-CD1 3.81Å; F120-F469 AromaticContact CD2-CD2 3.76Å; F120-F469 HydrophobicContact CD2-CD2 3.76Å; F120-F469 HydrophobicContact CD2-CE1 4.11Å; F120-F469 HydrophobicContact CD2-CE2 4.09Å; F120-F469 AromaticContact CD2-CG 3.61Å; F120-F469 HydrophobicContact CD2-CG 3.61Å; F120-F469 HydrophobicContact CD2-CZ 4.24Å; F120-F469 HydrophobicContact CE2-CB 4.39Å; F120-F469 AromaticContact CE2-CD2 3.89Å; F120-F469 HydrophobicContact CE2-CD2 3.89Å; F120-F469 HydrophobicContact CE2-CE2 4.34Å; F120-F469 HydrophobicContact CE2-CG 4.09Å; R293-F469 HydrophobicContact CG-CD1 4.35Å; R293-F469 HydrophobicContact CG-CE1 3.73Å; R293-F469 HydrophobicContact CG-CE2 4.06Å; R293-F469 HydrophobicContact CG-CZ 3.57Å; R293-F469 PolarHBondContact NE-O 2.93Å; R293-F469 PolarHBondContact NH2-O 3.37Å; V464-F469 WeakPolarHBondContact O-CB 3.34Å; F469-C555 WeakPolarHBondContact CE2-SG 3.3Å
470	G	90.2	Very high	94.9	Very high	15 Å²	15	58.5 Å²	58.5	16%	0.155	29%	0.286	C	S	.	.			trans	-73	148.6	177.8	0	0	0	0	0	112.8	I466	I466-G470 PolarHBondContact O-N 2.92Å; I466-G470 VanDerWaalsContact O-N 3.16Å
471	I	90.1	Very high	95	Very high	91 Å²	91	54.3 Å²	54.3	47%	0.467	27%	0.274	S	S	.	.	S	Bend	trans	-97.8	-53.5	-177.9	-56.5	172.1	0	0	0	110.9	R293	R293-I471 HydrophobicContact CB-CD1 3.8Å; R293-I471 HydrophobicContact CB-CG1 4Å; R293-I471 PolarHBondContact O-N 3.43Å
472	N	88.2	Confident	95	Very high	102 Å²	102	57.8 Å²	57.8	55%	0.545	30%	0.296	S	S	.	.	S	Bend	trans	-120.8	48	-170.5	-69.7	-42.6	0	0	0	113.8	D294 R296	D294-N472 WeakPolarHBondContact OD1-CB 3.3Å; D294-N472 PolarHBondContact OD1-ND2 3.42Å; R296-N472 VanDerWaalsContact CD-O 3.3Å; R296-N472 WeakPolarHBondContact CD-O 3.39Å; R296-N472 WeakPolarHBondContact CG-O 3.46Å
473	D	93.9	Very high	95	Very high	33 Å²	33	58 Å²	58	18%	0.176	30%	0.299	C	S	.	.	S	Bend	trans	-126.3	164.9	-178.8	-157.7	7.2	0	0	0	113.1	R296 I297 V298 S299	R296-D473 VanDerWaalsContact CA-CG 3.42Å; R296-D473 VanDerWaalsContact CA-OD2 3.28Å; R296-D473 WeakPolarHBondContact CA-OD2 3.42Å; R296-D473 HydrophobicContact CB-CB 4.3Å; R296-D473 WeakPolarHBondContact CB-OD1 3.44Å; R296-D473 HydrophobicContact CG-CB 4.27Å; R296-D473 IonicContact NE-OD1 3.77Å; I297-D473 PolarHBondContact N-OD2 3.25Å; V298-D473 WeakPolarHBondContact CA-OD2 3.3Å; V298-D473 WeakPolarHBondContact CB-OD2 3.2Å; V298-D473 PolarHBondContact N-OD2 3.35Å; S299-D473 PolarHBondContact N-OD1 2.87Å; S299-D473 PolarHBondContact OG-OD1 3.5Å
474	C	93.6	Very high	95.1	Very high	61 Å²	61	52.2 Å²	52.2	41%	0.412	28%	0.278	S	S	.	.	P	Polyproline II helix	trans	-68.2	140.1	172.4	59.5	0	0	0	0	110.8	V298 L476	V298-C474 WeakPolarHBondContact CG1-SG 3.5Å; C474-L476 PolarHBondContact O-N 3.22Å
475	H	93.9	Very high	95.3	Very high	150 Å²	150	52.6 Å²	52.6	69%	0.694	28%	0.283	S	S	*	.	P	Polyproline II helix	trans	-68.6	126.3	174.8	-78.7	83.3	0	0	0	109.9	S477	H475-S477 PolarHBondContact O-N 3.4Å
476	L	97.3	Very high	95.4	Very high	10 Å²	10	59.4 Å²	59.4	5%	0.052	31%	0.313	C	S	.	.	P	Polyproline II helix	trans	-69.7	125.1	174.6	-176.5	59.9	0	0	0	110.3	I112 V298 R462 I466 N467 C474 W480	I112-L476 HydrophobicContact CD1-CD1 3.82Å; I112-L476 HydrophobicContact CD1-CD2 4.3Å; I112-L476 HydrophobicContact CG2-CD2 3.6Å; V298-L476 HydrophobicContact CG1-CB 4.46Å; V298-L476 HydrophobicContact CG1-CD1 4.16Å; V298-L476 HydrophobicContact CG2-CB 4.26Å; R462-L476 WeakPolarHBondContact CD-O 3.36Å; R462-L476 HydrophobicContact CG-CB 4.24Å; R462-L476 HydrophobicContact CG-CD2 4.12Å; R462-L476 HydrophobicContact CG-CG 4.22Å; R462-L476 PolarHBondContact NH1-O 3Å; I466-L476 HydrophobicContact CD1-CD2 3.49Å; I466-L476 VanDerWaalsContact CD1-CD2 3.49Å; I466-L476 HydrophobicContact CG2-CB 3.97Å; I466-L476 HydrophobicContact CG2-CD2 4.23Å; N467-L476 PolarHBondContact ND2-O 3.34Å; N467-L476 WeakPolarHBondContact OD1-CB 3.35Å; N467-L476 PolarHBondContact OD1-N 3.43Å; C474-L476 PolarHBondContact O-N 3.22Å; L476-W480 HydrophobicContact CD1-CB 3.92Å; L476-W480 HydrophobicContact CD1-CG 4.13Å; L476-W480 HydrophobicContact CD2-CB 4.05Å; L476-W480 HydrophobicContact CD2-CD2 3.6Å; L476-W480 HydrophobicContact CD2-CE3 3.9Å; L476-W480 HydrophobicContact CD2-CG 3.67Å; L476-W480 HydrophobicContact CG-CB 3.93Å; L476-W480 HydrophobicContact CG-CD2 4.43Å; L476-W480 HydrophobicContact CG-CG 4.1Å
477	S	96.6	Very high	95.4	Very high	58 Å²	58	61.4 Å²	61.4	41%	0.406	32%	0.324	S	S	.	.	P	Polyproline II helix	trans	-64.7	151.4	-179.2	-177.1	0	0	0	0	112.7	R462 H475 F479 W480	R462-S477 WeakPolarHBondContact CD-O 3.48Å; H475-S477 PolarHBondContact O-N 3.4Å; S477-F479 PolarHBondContact O-N 3.32Å; S477-F479 WeakPolarHBondContact OG-CD2 3.47Å; S477-F479 PolarHBondContact OG-N 3.37Å; S477-W480 WeakPolarHBondContact O-CB 3.49Å; S477-W480 PolarHBondContact O-N 2.65Å
478	I	97.4	Very high	95.4	Very high	100 Å²	100	60.4 Å²	60.4	51%	0.513	32%	0.318	S	S	.	.	T	Hydrogen-bonded Turn	trans	-63	-21.9	174.3	-165.1	161.9	0	0	0	112.7	W480 V481 P482	I478-W480 PolarHBondContact O-N 3.43Å; I478-W480 VanDerWaalsContact O-N 3.14Å; I478-V481 HydrophobicContact CG1-CG2 4.4Å; I478-V481 VanDerWaalsContact O-CB 3.31Å; I478-V481 WeakPolarHBondContact O-CB 3.46Å; I478-V481 PolarHBondContact O-N 3.48Å; I478-P482 WeakPolarHBondContact O-CD 3.45Å
479	F	97.1	Very high	95.6	Very high	160 Å²	160	56.2 Å²	56.2	70%	0.702	30%	0.3	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.2	-22	174.4	-66.6	-62.4	0	0	0	113.5	S477 V481 P482 L483	S477-F479 PolarHBondContact O-N 3.32Å; S477-F479 WeakPolarHBondContact OG-CD2 3.47Å; S477-F479 PolarHBondContact OG-N 3.37Å; F479-V481 PolarHBondContact O-N 3.41Å; F479-P482 VanDerWaalsContact O-CD 3.25Å; F479-P482 WeakPolarHBondContact O-CD 3.28Å; F479-P482 VanDerWaalsContact O-CG 3.31Å; F479-P482 WeakPolarHBondContact O-CG 3.36Å; F479-L483 WeakPolarHBondContact O-CG 3.39Å
480	W	98.4	Very high	95.7	Very high	10 Å²	10	59.8 Å²	59.8	4%	0.038	32%	0.319	C	S	.	.	H	α-helix	trans	-64.2	-30.2	173.5	175.1	83	0	0	0	112.7	P109 I112 V113 V453 Y461 R462 I466 L476 S477 I478 L483 I484	P109-W480 PolarHBondContact O-NE1 3.48Å; P109-W480 VanDerWaalsContact O-NE1 3.17Å; I112-W480 HydrophobicContact CG2-CZ2 4.08Å; V113-W480 HydrophobicContact CG2-CH2 4.31Å; V113-W480 HydrophobicContact CG2-CZ2 3.68Å; V453-W480 HydrophobicContact CG1-CH2 3.8Å; V453-W480 HydrophobicContact CG1-CZ3 4.23Å; V453-W480 HydrophobicContact CG2-CH2 4.29Å; Y461-W480 AromaticContact CD1-CH2 3.65Å; Y461-W480 HydrophobicContact CD1-CH2 3.65Å; Y461-W480 HydrophobicContact CD1-CZ3 4.22Å; Y461-W480 HydrophobicContact CE1-CH2 4.14Å; Y461-W480 HydrophobicContact CG-CH2 4.49Å; R462-W480 HydrophobicContact CB-CE3 4.07Å; R462-W480 HydrophobicContact CB-CZ3 3.93Å; R462-W480 HydrophobicContact CG-CE3 4.25Å; I466-W480 HydrophobicContact CD1-CH2 4.32Å; L476-W480 HydrophobicContact CD1-CB 3.92Å; L476-W480 HydrophobicContact CD1-CG 4.13Å; L476-W480 HydrophobicContact CD2-CB 4.05Å; L476-W480 HydrophobicContact CD2-CD2 3.6Å; L476-W480 HydrophobicContact CD2-CE3 3.9Å; L476-W480 HydrophobicContact CD2-CG 3.67Å; L476-W480 HydrophobicContact CG-CB 3.93Å; L476-W480 HydrophobicContact CG-CD2 4.43Å; L476-W480 HydrophobicContact CG-CG 4.1Å; S477-W480 WeakPolarHBondContact O-CB 3.49Å; S477-W480 PolarHBondContact O-N 2.65Å; I478-W480 PolarHBondContact O-N 3.43Å; I478-W480 VanDerWaalsContact O-N 3.14Å; W480-L483 WeakPolarHBondContact O-CB 3.42Å; W480-L483 PolarHBondContact O-N 3.03Å; W480-I484 HydrophobicContact CD2-CB 4.33Å; W480-I484 HydrophobicContact CD2-CG2 3.94Å; W480-I484 HydrophobicContact CE3-CG2 3.87Å; W480-I484 HydrophobicContact CH2-CB 4.36Å; W480-I484 HydrophobicContact CH2-CG1 4.28Å; W480-I484 HydrophobicContact CH2-CG2 3.74Å; W480-I484 HydrophobicContact CZ2-CB 3.91Å; W480-I484 HydrophobicContact CZ2-CD1 4.5Å; W480-I484 HydrophobicContact CZ2-CG1 3.8Å; W480-I484 HydrophobicContact CZ2-CG2 3.79Å; W480-I484 HydrophobicContact CZ3-CG2 3.77Å; W480-I484 WeakPolarHBondContact O-CG2 3.41Å; W480-I484 PolarHBondContact O-N 2.84Å
481	V	98.6	Very high	95.8	Very high	28 Å²	28	61 Å²	61	17%	0.17	32%	0.321	C	S	.	.	H	α-helix	trans	-59	-55.5	-177	170.5	0	0	0	0	113	P458 N459 I478 F479 L483 I484 A485	P458-V481 HydrophobicContact CB-CG1 3.77Å; P458-V481 HydrophobicContact CB-CG2 4.49Å; N459-V481 HydrophobicContact CB-CG2 4.38Å; I478-V481 HydrophobicContact CG1-CG2 4.4Å; I478-V481 VanDerWaalsContact O-CB 3.31Å; I478-V481 WeakPolarHBondContact O-CB 3.46Å; I478-V481 PolarHBondContact O-N 3.48Å; F479-V481 PolarHBondContact O-N 3.41Å; V481-L483 PolarHBondContact O-N 3Å; V481-I484 PolarHBondContact O-N 2.95Å; V481-A485 WeakPolarHBondContact O-CB 3.31Å; V481-A485 PolarHBondContact O-N 2.85Å
482	P	98.4	Very high	96	Very high	73 Å²	73	56.7 Å²	56.7	47%	0.474	30%	0.299	S	S	.	.	H	α-helix	trans	-63.7	-27.9	177.5	24.4	-35.1	0	0	0	113	I478 F479 F486 L487	I478-P482 WeakPolarHBondContact O-CD 3.45Å; F479-P482 VanDerWaalsContact O-CD 3.25Å; F479-P482 WeakPolarHBondContact O-CD 3.28Å; F479-P482 VanDerWaalsContact O-CG 3.31Å; F479-P482 WeakPolarHBondContact O-CG 3.36Å; P482-F486 WeakPolarHBondContact O-CB 3.25Å; P482-F486 PolarHBondContact O-N 2.83Å; P482-F486 VanDerWaalsContact O-N 3.14Å; P482-L487 PolarHBondContact O-N 3.44Å; P482-L487 VanDerWaalsContact O-N 3.15Å
483	L	98	Very high	96.3	Very high	38 Å²	38	56 Å²	56	20%	0.199	30%	0.298	C	S	.	.	I	π-helix	trans	-65.5	-58	176	-57.8	-178.6	0	0	0	110.5	F105 P109 F479 W480 V481 A485 L487 V488	F105-L483 HydrophobicContact CD1-CD1 4.29Å; F105-L483 HydrophobicContact CD1-CD2 3.81Å; F105-L483 HydrophobicContact CE1-CD2 4.32Å; P109-L483 HydrophobicContact CG-CB 4.26Å; P109-L483 HydrophobicContact CG-CD1 4.24Å; F479-L483 WeakPolarHBondContact O-CG 3.39Å; W480-L483 WeakPolarHBondContact O-CB 3.42Å; W480-L483 PolarHBondContact O-N 3.03Å; V481-L483 PolarHBondContact O-N 3Å; L483-A485 PolarHBondContact O-N 3.03Å; L483-L487 HydrophobicContact CD2-CB 4.4Å; L483-L487 HydrophobicContact CD2-CD2 3.63Å; L483-L487 PolarHBondContact O-N 2.77Å; L483-L487 VanDerWaalsContact O-N 3.12Å; L483-V488 WeakPolarHBondContact O-CG2 3.4Å; L483-V488 PolarHBondContact O-N 3.05Å
484	I	98.4	Very high	96.1	Very high	0 Å²	0	57 Å²	57	0%	0	31%	0.311	C	S	.	.	I	π-helix	trans	-71.9	-30	-174.6	-163.1	63.5	0	0	0	113.2	P109 I110 V113 V453 W480 V481 P489	P109-I484 HydrophobicContact CB-CD1 4.14Å; I110-I484 HydrophobicContact CG1-CD1 4.31Å; V113-I484 HydrophobicContact CG2-CD1 3.79Å; V113-I484 HydrophobicContact CG2-CG1 3.94Å; V453-I484 HydrophobicContact CB-CG1 4.38Å; V453-I484 HydrophobicContact CG1-CG1 4.28Å; V453-I484 HydrophobicContact CG1-CG2 3.89Å; V453-I484 HydrophobicContact CG2-CG1 4.34Å; W480-I484 HydrophobicContact CD2-CB 4.33Å; W480-I484 HydrophobicContact CD2-CG2 3.94Å; W480-I484 HydrophobicContact CE3-CG2 3.87Å; W480-I484 HydrophobicContact CH2-CB 4.36Å; W480-I484 HydrophobicContact CH2-CG1 4.28Å; W480-I484 HydrophobicContact CH2-CG2 3.74Å; W480-I484 HydrophobicContact CZ2-CB 3.91Å; W480-I484 HydrophobicContact CZ2-CD1 4.5Å; W480-I484 HydrophobicContact CZ2-CG1 3.8Å; W480-I484 HydrophobicContact CZ2-CG2 3.79Å; W480-I484 HydrophobicContact CZ3-CG2 3.77Å; W480-I484 WeakPolarHBondContact O-CG2 3.41Å; W480-I484 PolarHBondContact O-N 2.84Å; V481-I484 PolarHBondContact O-N 2.95Å; I484-P489 VanDerWaalsContact O-CD 3.29Å; I484-P489 WeakPolarHBondContact O-CD 3.44Å; I484-P489 WeakPolarHBondContact O-CG 3.31Å
485	A	98.3	Very high	95.9	Very high	31 Å²	31	55.3 Å²	55.3	26%	0.256	30%	0.298	S	S	.	.	I	π-helix	trans	-90	-21.2	-174.9	0	0	0	0	0	113.8	I454 P458 V481 L483	I454-A485 HydrophobicContact CG1-CB 4.2Å; P458-A485 HydrophobicContact CB-CB 4.1Å; P458-A485 HydrophobicContact CG-CB 3.6Å; V481-A485 WeakPolarHBondContact O-CB 3.31Å; V481-A485 PolarHBondContact O-N 2.85Å; L483-A485 PolarHBondContact O-N 3.03Å
486	F	97.7	Very high	95.8	Very high	144 Å²	144	49.3 Å²	49.3	63%	0.632	27%	0.27	S	S	*	.	I	π-helix	trans	-132	-57.5	-176.2	-176.4	-100.1	0	0	0	112.7	P482 P489 L490	P482-F486 WeakPolarHBondContact O-CB 3.25Å; P482-F486 PolarHBondContact O-N 2.83Å; P482-F486 VanDerWaalsContact O-N 3.14Å; F486-P489 WeakPolarHBondContact O-CD 3.41Å; F486-L490 HydrophobicContact CE1-CD2 4.11Å; F486-L490 HydrophobicContact CZ-CD2 4.28Å; F486-L490 WeakPolarHBondContact O-CB 3.24Å; F486-L490 PolarHBondContact O-N 3.46Å
487	L	96.4	Very high	95.6	Very high	47 Å²	47	50.5 Å²	50.5	25%	0.246	29%	0.285	C	S	.	.	I	π-helix	trans	-62.6	-54.3	-173	-176	64.5	0	0	0	112.3	F105 P482 L483 L490 Q491	F105-L487 HydrophobicContact CB-CD2 3.91Å; F105-L487 HydrophobicContact CD1-CD2 4.12Å; F105-L487 HydrophobicContact CG-CD2 4.34Å; P482-L487 PolarHBondContact O-N 3.44Å; P482-L487 VanDerWaalsContact O-N 3.15Å; L483-L487 HydrophobicContact CD2-CB 4.4Å; L483-L487 HydrophobicContact CD2-CD2 3.63Å; L483-L487 PolarHBondContact O-N 2.77Å; L483-L487 VanDerWaalsContact O-N 3.12Å; L487-L490 WeakPolarHBondContact O-CB 3.42Å; L487-L490 PolarHBondContact O-N 3.11Å; L487-Q491 HydrophobicContact CD1-CG 4.17Å; L487-Q491 HydrophobicContact CG-CG 4.3Å; L487-Q491 WeakPolarHBondContact O-CB 3.48Å; L487-Q491 WeakPolarHBondContact O-CG 3.43Å; L487-Q491 PolarHBondContact O-N 3.14Å
488	V	96.2	Very high	95.3	Very high	0 Å²	0	52 Å²	52	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-64.5	-44.8	-176.1	-178.5	0	0	0	0	112.6	F105 W106 P109 I110 C450 L483 L490 Q491 S492	F105-V488 VanDerWaalsContact O-CG2 3.3Å; F105-V488 WeakPolarHBondContact O-CG2 3.45Å; W106-V488 HydrophobicContact CD2-CG1 4.32Å; W106-V488 HydrophobicContact CG-CG1 4.41Å; P109-V488 HydrophobicContact CB-CG2 4.14Å; P109-V488 HydrophobicContact CG-CG2 4.46Å; I110-V488 HydrophobicContact CD1-CG1 3.67Å; I110-V488 HydrophobicContact CG1-CG1 3.85Å; C450-V488 VanDerWaalsContact SG-CG1 3.5Å; L483-V488 WeakPolarHBondContact O-CG2 3.4Å; L483-V488 PolarHBondContact O-N 3.05Å; V488-L490 VanDerWaalsContact C-N 3.34Å; V488-L490 PolarHBondContact O-N 2.98Å; V488-Q491 PolarHBondContact O-N 3.18Å; V488-S492 WeakPolarHBondContact O-CB 3.43Å; V488-S492 PolarHBondContact O-N 3.07Å; V488-S492 PolarHBondContact O-OG 3.3Å
489	P	96.7	Very high	94.8	Very high	13 Å²	13	48.2 Å²	48.2	8%	0.084	26%	0.261	C	S	.	.	H	α-helix	trans	-57.2	-45.1	171.5	-24.3	30.2	0	0	0	113.2	F447 C450 I454 I484 F486 Q491 S492 V493	F447-P489 HydrophobicContact CD2-CB 4.19Å; F447-P489 HydrophobicContact CE2-CB 4.02Å; C450-P489 HydrophobicContact CB-CG 3.75Å; I454-P489 HydrophobicContact CD1-CG 3.82Å; I484-P489 VanDerWaalsContact O-CD 3.29Å; I484-P489 WeakPolarHBondContact O-CD 3.44Å; I484-P489 WeakPolarHBondContact O-CG 3.31Å; F486-P489 WeakPolarHBondContact O-CD 3.41Å; P489-Q491 VanDerWaalsContact C-N 3.34Å; P489-Q491 PolarHBondContact O-N 3.41Å; P489-S492 WeakPolarHBondContact O-CB 3.42Å; P489-S492 PolarHBondContact O-N 3.35Å; P489-V493 WeakPolarHBondContact O-CG2 3.36Å; P489-V493 PolarHBondContact O-N 3.35Å
490	L	95	Very high	94.6	Very high	92 Å²	92	43.8 Å²	43.8	48%	0.482	24%	0.244	S	C	.	.	H	α-helix	trans	-60.9	-45.9	178.8	176.1	64.9	0	0	0	110.8	F486 L487 V488 S492 V493 A494	F486-L490 HydrophobicContact CE1-CD2 4.11Å; F486-L490 HydrophobicContact CZ-CD2 4.28Å; F486-L490 WeakPolarHBondContact O-CB 3.24Å; F486-L490 PolarHBondContact O-N 3.46Å; L487-L490 WeakPolarHBondContact O-CB 3.42Å; L487-L490 PolarHBondContact O-N 3.11Å; V488-L490 VanDerWaalsContact C-N 3.34Å; V488-L490 PolarHBondContact O-N 2.98Å; L490-S492 VanDerWaalsContact C-N 3.33Å; L490-S492 PolarHBondContact O-N 3.01Å; L490-V493 PolarHBondContact O-N 3.01Å; L490-A494 VanDerWaalsContact O-CB 3.28Å; L490-A494 WeakPolarHBondContact O-CB 3.37Å; L490-A494 PolarHBondContact O-N 2.76Å
491	Q	91.9	Very high	94.3	Very high	40 Å²	40	49.8 Å²	49.8	19%	0.187	27%	0.267	C	S	.	.	H	α-helix	trans	-63.4	-39.8	177.4	-65	169.5	-23.9	0	0	111	W106 L487 V488 P489 V493 A494 L495	W106-Q491 HydrophobicContact CE3-CB 3.43Å; W106-Q491 VanDerWaalsContact CE3-CB 3.43Å; W106-Q491 HydrophobicContact CE3-CG 4.25Å; W106-Q491 HydrophobicContact CH2-CB 4.23Å; W106-Q491 VanDerWaalsContact CZ3-C 3.44Å; W106-Q491 HydrophobicContact CZ3-CB 3.19Å; W106-Q491 HydrophobicContact CZ3-CG 4.4Å; L487-Q491 HydrophobicContact CD1-CG 4.17Å; L487-Q491 HydrophobicContact CG-CG 4.3Å; L487-Q491 WeakPolarHBondContact O-CB 3.48Å; L487-Q491 WeakPolarHBondContact O-CG 3.43Å; L487-Q491 PolarHBondContact O-N 3.14Å; V488-Q491 PolarHBondContact O-N 3.18Å; P489-Q491 VanDerWaalsContact C-N 3.34Å; P489-Q491 PolarHBondContact O-N 3.41Å; Q491-V493 PolarHBondContact O-N 3.45Å; Q491-A494 PolarHBondContact O-N 2.83Å; Q491-L495 WeakPolarHBondContact O-CB 3.3Å; Q491-L495 VanDerWaalsContact O-CG 3.29Å; Q491-L495 WeakPolarHBondContact O-CG 3.37Å; Q491-L495 PolarHBondContact O-N 3.37Å
492	S	93.3	Very high	93.8	Very high	1 Å²	1	51.9 Å²	51.9	1%	0.007	28%	0.275	C	S	.	.	H	α-helix	trans	-59.6	-47	175.3	-57.3	0	0	0	0	112.8	W106 V488 P489 L490 L496	W106-S492 VanDerWaalsContact CH2-CA 3.49Å; W106-S492 WeakPolarHBondContact CH2-OG 3.42Å; W106-S492 WeakPolarHBondContact CZ2-OG 3.24Å; V488-S492 WeakPolarHBondContact O-CB 3.43Å; V488-S492 PolarHBondContact O-N 3.07Å; V488-S492 PolarHBondContact O-OG 3.3Å; P489-S492 WeakPolarHBondContact O-CB 3.42Å; P489-S492 PolarHBondContact O-N 3.35Å; L490-S492 VanDerWaalsContact C-N 3.33Å; L490-S492 PolarHBondContact O-N 3.01Å; S492-L496 PolarHBondContact O-N 2.91Å
493	V	94.3	Very high	93.4	Very high	87 Å²	87	49.6 Å²	49.6	53%	0.527	26%	0.261	S	S	.	.	H	α-helix	trans	-65.6	-41.7	176.2	174.4	0	0	0	0	111	F447 P489 L490 Q491 G497	F447-V493 HydrophobicContact CD2-CG2 4.39Å; F447-V493 HydrophobicContact CE2-CG2 4.08Å; P489-V493 WeakPolarHBondContact O-CG2 3.36Å; P489-V493 PolarHBondContact O-N 3.35Å; L490-V493 PolarHBondContact O-N 3.01Å; Q491-V493 PolarHBondContact O-N 3.45Å; V493-G497 PolarHBondContact O-N 3.47Å
494	A	91.1	Very high	93.3	Very high	55 Å²	55	51.1 Å²	51.1	46%	0.455	27%	0.269	S	S	.	.	H	α-helix	trans	-64.6	-43.4	179	0	0	0	0	0	112.4	L490 Q491 W498	L490-A494 VanDerWaalsContact O-CB 3.28Å; L490-A494 WeakPolarHBondContact O-CB 3.37Å; L490-A494 PolarHBondContact O-N 2.76Å; Q491-A494 PolarHBondContact O-N 2.83Å; A494-W498 VanDerWaalsContact O-CB 3.23Å; A494-W498 WeakPolarHBondContact O-CB 3.45Å; A494-W498 PolarHBondContact O-N 2.78Å
495	L	89.7	Confident	93	Very high	24 Å²	24	54.9 Å²	54.9	13%	0.126	29%	0.292	C	S	.	.	H	α-helix	trans	-61.4	-49	177.5	-71.3	-167.2	0	0	0	111.4	W106 I267 A270 V443 Q491 W499	W106-L495 HydrophobicContact CE3-CD1 4.47Å; W106-L495 HydrophobicContact CH2-CD1 3.34Å; W106-L495 HydrophobicContact CH2-CG 3.99Å; W106-L495 HydrophobicContact CZ2-CD1 4.28Å; W106-L495 HydrophobicContact CZ3-CD1 3.42Å; W106-L495 VanDerWaalsContact CZ3-CD1 3.42Å; W106-L495 HydrophobicContact CZ3-CG 3.88Å; I267-L495 HydrophobicContact CB-CD2 4.04Å; I267-L495 HydrophobicContact CG1-CD2 3.57Å; I267-L495 HydrophobicContact CG2-CD2 4.13Å; A270-L495 HydrophobicContact CB-CD1 3.89Å; A270-L495 HydrophobicContact CB-CD2 4.27Å; V443-L495 HydrophobicContact CG1-CB 4.49Å; Q491-L495 WeakPolarHBondContact O-CB 3.3Å; Q491-L495 VanDerWaalsContact O-CG 3.29Å; Q491-L495 WeakPolarHBondContact O-CG 3.37Å; Q491-L495 PolarHBondContact O-N 3.37Å; L495-W499 WeakPolarHBondContact O-CB 3.38Å; L495-W499 PolarHBondContact O-N 3.37Å
496	L	91.6	Very high	92.6	Very high	24 Å²	24	58.4 Å²	58.4	13%	0.126	31%	0.31	C	S	.	.	H	α-helix	trans	-67.3	-44.5	179.9	-72.6	172.6	0	0	0	111.8	V443 I444 S492 W498 W499 M500 W525	V443-L496 HydrophobicContact CB-CD1 4.34Å; V443-L496 HydrophobicContact CB-CD2 4.1Å; V443-L496 HydrophobicContact CB-CG 4.14Å; V443-L496 HydrophobicContact CG1-CD1 4.02Å; V443-L496 HydrophobicContact CG1-CD2 4.31Å; V443-L496 HydrophobicContact CG1-CG 3.8Å; I444-L496 HydrophobicContact CG1-CD1 3.7Å; S492-L496 PolarHBondContact O-N 2.91Å; L496-W498 VanDerWaalsContact C-N 3.35Å; L496-W498 PolarHBondContact O-N 2.77Å; L496-W499 HydrophobicContact CD2-CE3 4.29Å; L496-W499 PolarHBondContact O-N 2.97Å; L496-M500 HydrophobicContact CB-CE 4.25Å; L496-M500 VanDerWaalsContact O-CE 3.29Å; L496-M500 WeakPolarHBondContact O-CE 3.33Å; L496-M500 WeakPolarHBondContact O-CG 3.43Å; L496-M500 PolarHBondContact O-N 2.88Å; L496-W525 HydrophobicContact CD2-CH2 4.25Å
497	G	92.4	Very high	92.3	Very high	35 Å²	35	53.8 Å²	53.8	36%	0.361	29%	0.292	S	S	.	.	H	α-helix	trans	-59.9	-44.5	177.8	0	0	0	0	0	112.2	V493 Y501	V493-G497 PolarHBondContact O-N 3.47Å; G497-Y501 WeakPolarHBondContact O-CB 3.49Å; G497-Y501 PolarHBondContact O-N 3.36Å
498	W	89.6	Confident	92	Very high	90 Å²	90	56.5 Å²	56.5	34%	0.341	31%	0.312	S	S	.	.	H	α-helix	trans	-66.1	-48	176.2	-177.9	-80.3	0	0	0	112.2	P263 I267 A494 L496 M500 Y501 E502	P263-W498 HydrophobicContact CB-CH2 4.06Å; P263-W498 HydrophobicContact CB-CZ2 4.05Å; P263-W498 HydrophobicContact CB-CZ3 4.36Å; P263-W498 HydrophobicContact CG-CH2 4.15Å; I267-W498 HydrophobicContact CD1-CB 3.79Å; I267-W498 HydrophobicContact CD1-CD2 3.97Å; I267-W498 HydrophobicContact CD1-CG 3.28Å; A494-W498 VanDerWaalsContact O-CB 3.23Å; A494-W498 WeakPolarHBondContact O-CB 3.45Å; A494-W498 PolarHBondContact O-N 2.78Å; L496-W498 VanDerWaalsContact C-N 3.35Å; L496-W498 PolarHBondContact O-N 2.77Å; W498-M500 VanDerWaalsContact C-N 3.25Å; W498-M500 PolarHBondContact O-N 3.23Å; W498-Y501 CarbonylContact O-C 3.09Å; W498-Y501 WeakPolarHBondContact O-CA 3.45Å; W498-Y501 WeakPolarHBondContact O-CB 3.24Å; W498-Y501 PolarHBondContact O-N 3.11Å; W498-E502 PolarHBondContact NE1-OE2 3.1Å; W498-E502 WeakPolarHBondContact O-CB 3.24Å; W498-E502 PolarHBondContact O-N 3.28Å
499	W	88.3	Confident	91.8	Very high	21 Å²	21	62.6 Å²	62.6	8%	0.08	34%	0.339	C	S	.	.	H	α-helix	trans	-56.7	-41.8	178.8	162.3	61.7	0	0	0	111.9	Y440 L495 L496 E502 S503 L518 T521 W525	Y440-W499 HydrophobicContact CD1-CB 4.48Å; Y440-W499 AromaticContact CD1-CD2 3.83Å; Y440-W499 HydrophobicContact CD1-CD2 3.83Å; Y440-W499 HydrophobicContact CD1-CE3 4.13Å; Y440-W499 AromaticContact CD1-CG 3.97Å; Y440-W499 HydrophobicContact CD1-CG 3.97Å; Y440-W499 AromaticContact CD2-CD2 3.88Å; Y440-W499 HydrophobicContact CD2-CD2 3.88Å; Y440-W499 AromaticContact CD2-CE2 3.43Å; Y440-W499 VanDerWaalsContact CD2-CE2 3.43Å; Y440-W499 HydrophobicContact CD2-CE3 4.32Å; Y440-W499 HydrophobicContact CD2-CG 4.48Å; Y440-W499 AromaticContact CD2-CH2 3.99Å; Y440-W499 HydrophobicContact CD2-CH2 3.99Å; Y440-W499 AromaticContact CD2-CZ2 3.49Å; Y440-W499 HydrophobicContact CD2-CZ2 3.49Å; Y440-W499 VanDerWaalsContact CD2-CZ2 3.49Å; Y440-W499 HydrophobicContact CD2-CZ3 4.38Å; Y440-W499 AromaticContact CD2-NE1 3.84Å; Y440-W499 HydrophobicContact CE1-CB 3.96Å; Y440-W499 AromaticContact CE1-CD1 3.61Å; Y440-W499 AromaticContact CE1-CD2 3.77Å; Y440-W499 HydrophobicContact CE1-CD2 3.77Å; Y440-W499 AromaticContact CE1-CG 3.45Å; Y440-W499 HydrophobicContact CE1-CG 3.45Å; Y440-W499 VanDerWaalsContact CE1-CG 3.45Å; Y440-W499 AromaticContact CE1-NE1 3.96Å; Y440-W499 AromaticContact CE2-CD1 3.67Å; Y440-W499 AromaticContact CE2-CD2 3.86Å; Y440-W499 HydrophobicContact CE2-CD2 3.86Å; Y440-W499 AromaticContact CE2-CE2 3.27Å; Y440-W499 HydrophobicContact CE2-CG 4.07Å; Y440-W499 AromaticContact CE2-CZ2 3.7Å; Y440-W499 HydrophobicContact CE2-CZ2 3.7Å; Y440-W499 AromaticContact CE2-NE1 3.14Å; Y440-W499 AromaticContact CG-CD2 3.9Å; Y440-W499 HydrophobicContact CG-CD2 3.9Å; Y440-W499 AromaticContact CG-CE2 3.96Å; Y440-W499 HydrophobicContact CG-CE3 4.05Å; Y440-W499 HydrophobicContact CG-CG 4.46Å; Y440-W499 HydrophobicContact CG-CH2 4.3Å; Y440-W499 HydrophobicContact CG-CZ2 4.16Å; Y440-W499 HydrophobicContact CG-CZ3 4.25Å; Y440-W499 AromaticContact CZ-CD1 3.17Å; Y440-W499 AromaticContact CZ-CD2 3.8Å; Y440-W499 AromaticContact CZ-CE2 3.61Å; Y440-W499 AromaticContact CZ-CG 3.52Å; Y440-W499 AromaticContact CZ-NE1 3.21Å; Y440-W499 PolarHBondContact OH-NE1 3.05Å; L495-W499 WeakPolarHBondContact O-CB 3.38Å; L495-W499 PolarHBondContact O-N 3.37Å; L496-W499 HydrophobicContact CD2-CE3 4.29Å; L496-W499 PolarHBondContact O-N 2.97Å; W499-E502 PolarHBondContact O-N 3.4Å; W499-S503 PolarHBondContact NE1-OG 3.03Å; W499-S503 WeakPolarHBondContact O-CB 3.47Å; W499-S503 PolarHBondContact O-N 3.16Å; W499-S503 PolarHBondContact O-OG 3.35Å; W499-L518 HydrophobicContact CH2-CD1 3.44Å; W499-L518 VanDerWaalsContact CH2-CD1 3.44Å; W499-L518 HydrophobicContact CZ2-CD1 3.73Å; W499-L518 HydrophobicContact CZ3-CD1 3.92Å; W499-T521 HydrophobicContact CH2-CG2 3.57Å; W499-T521 HydrophobicContact CZ2-CG2 4.11Å; W499-W525 HydrophobicContact CH2-CH2 4.12Å; W499-W525 AromaticContact CZ3-CH2 3.73Å; W499-W525 HydrophobicContact CZ3-CH2 3.73Å; W499-W525 HydrophobicContact CZ3-CZ3 4.17Å
500	M	92.2	Very high	91.6	Very high	66 Å²	66	65.7 Å²	65.7	33%	0.325	35%	0.349	S	S	.	.	H	α-helix	trans	-62.8	-45.3	173.9	-72.6	-175.2	-82.9	0	0	111.8	L496 W498 S503 I504 L518	L496-M500 HydrophobicContact CB-CE 4.25Å; L496-M500 VanDerWaalsContact O-CE 3.29Å; L496-M500 WeakPolarHBondContact O-CE 3.33Å; L496-M500 WeakPolarHBondContact O-CG 3.43Å; L496-M500 PolarHBondContact O-N 2.88Å; W498-M500 VanDerWaalsContact C-N 3.25Å; W498-M500 PolarHBondContact O-N 3.23Å; M500-S503 PolarHBondContact O-N 3.48Å; M500-I504 WeakPolarHBondContact O-CB 3.33Å; M500-I504 WeakPolarHBondContact O-CD1 3.33Å; M500-I504 VanDerWaalsContact O-CG1 3.24Å; M500-I504 WeakPolarHBondContact O-CG1 3.45Å; M500-I504 PolarHBondContact O-N 2.99Å; M500-L518 HydrophobicContact CB-CD2 4.36Å; M500-L518 HydrophobicContact CG-CD1 4.03Å; M500-L518 HydrophobicContact CG-CD2 4.42Å
501	Y	92.3	Very high	91.6	Very high	137 Å²	137	66.2 Å²	66.2	54%	0.537	35%	0.347	S	S	.	.	H	α-helix	trans	-59.9	-46.5	176.2	172.8	-98	0	0	0	112.4	G497 W498 I504 T505	G497-Y501 WeakPolarHBondContact O-CB 3.49Å; G497-Y501 PolarHBondContact O-N 3.36Å; W498-Y501 CarbonylContact O-C 3.09Å; W498-Y501 WeakPolarHBondContact O-CA 3.45Å; W498-Y501 WeakPolarHBondContact O-CB 3.24Å; W498-Y501 PolarHBondContact O-N 3.11Å; Y501-I504 PolarHBondContact O-N 3.05Å; Y501-T505 HydrophobicContact CD2-CG2 4.15Å; Y501-T505 HydrophobicContact CE1-CG2 4.19Å; Y501-T505 HydrophobicContact CE2-CG2 3.74Å; Y501-T505 WeakPolarHBondContact O-CB 3.49Å; Y501-T505 WeakPolarHBondContact O-CG2 3.2Å; Y501-T505 PolarHBondContact O-N 2.97Å; Y501-T505 PolarHBondContact O-OG1 3.39Å
502	E	89.2	Confident	91.6	Very high	71 Å²	71	68.8 Å²	68.8	33%	0.332	36%	0.359	S	S	.	.	H	α-helix	trans	-63	-42.8	178	-176.6	172	171.4	0	0	111.2	W498 W499 I504 T505 T506	W498-E502 PolarHBondContact NE1-OE2 3.1Å; W498-E502 WeakPolarHBondContact O-CB 3.24Å; W498-E502 PolarHBondContact O-N 3.28Å; W499-E502 PolarHBondContact O-N 3.4Å; E502-I504 VanDerWaalsContact C-N 3.35Å; E502-I504 PolarHBondContact O-N 3.16Å; E502-T505 WeakPolarHBondContact CA-OG1 3.38Å; E502-T505 PolarHBondContact O-N 3.22Å; E502-T505 PolarHBondContact O-OG1 3.49Å; E502-T506 WeakPolarHBondContact O-CB 3.35Å; E502-T506 PolarHBondContact O-N 2.94Å; E502-T506 PolarHBondContact O-OG1 3.2Å
503	S	89.9	Confident	91.5	Very high	25 Å²	25	74.7 Å²	74.7	18%	0.175	39%	0.39	C	S	.	.	H	α-helix	trans	-62.7	-41.7	177.6	-58.8	0	0	0	0	111.8	W499 M500 D507	W499-S503 PolarHBondContact NE1-OG 3.03Å; W499-S503 WeakPolarHBondContact O-CB 3.47Å; W499-S503 PolarHBondContact O-N 3.16Å; W499-S503 PolarHBondContact O-OG 3.35Å; M500-S503 PolarHBondContact O-N 3.48Å; S503-D507 PolarHBondContact O-N 3.44Å
504	I	94	Very high	91.2	Very high	71 Å²	71	72.9 Å²	72.9	36%	0.364	38%	0.378	S	S	.	.	H	α-helix	trans	-69	-38.6	178.9	-70.4	166.1	0	0	0	111.9	M500 Y501 E502 W510 L518	M500-I504 WeakPolarHBondContact O-CB 3.33Å; M500-I504 WeakPolarHBondContact O-CD1 3.33Å; M500-I504 VanDerWaalsContact O-CG1 3.24Å; M500-I504 WeakPolarHBondContact O-CG1 3.45Å; M500-I504 PolarHBondContact O-N 2.99Å; Y501-I504 PolarHBondContact O-N 3.05Å; E502-I504 VanDerWaalsContact C-N 3.35Å; E502-I504 PolarHBondContact O-N 3.16Å; I504-W510 HydrophobicContact CB-CG 4.43Å; I504-W510 HydrophobicContact CG1-CD2 3.81Å; I504-W510 HydrophobicContact CG1-CE3 4.17Å; I504-W510 HydrophobicContact CG1-CG 4.09Å; I504-W510 HydrophobicContact CG1-CZ2 4.35Å; I504-L518 HydrophobicContact CD1-CD2 4Å; I504-L518 HydrophobicContact CG1-CD2 3.69Å
505	T	93.6	Very high	90.9	Very high	79 Å²	79	75.7 Å²	75.7	49%	0.485	38%	0.376	S	S	.	.	H	α-helix	trans	-83.3	-28.8	-175.4	51	0	0	0	0	113.2	Y501 E502	Y501-T505 HydrophobicContact CD2-CG2 4.15Å; Y501-T505 HydrophobicContact CE1-CG2 4.19Å; Y501-T505 HydrophobicContact CE2-CG2 3.74Å; Y501-T505 WeakPolarHBondContact O-CB 3.49Å; Y501-T505 WeakPolarHBondContact O-CG2 3.2Å; Y501-T505 PolarHBondContact O-N 2.97Å; Y501-T505 PolarHBondContact O-OG1 3.39Å; E502-T505 WeakPolarHBondContact CA-OG1 3.38Å; E502-T505 PolarHBondContact O-N 3.22Å; E502-T505 PolarHBondContact O-OG1 3.49Å
506	T	89.9	Confident	90.5	Very high	104 Å²	104	78.9 Å²	78.9	64%	0.638	40%	0.397	S	S	*	.	H	α-helix	trans	-88.4	-36.6	-178.1	-52.4	0	0	0	0	112.4	E502	E502-T506 WeakPolarHBondContact O-CB 3.35Å; E502-T506 PolarHBondContact O-N 2.94Å; E502-T506 PolarHBondContact O-OG1 3.2Å
507	D	90.4	Very high	90.4	Very high	48 Å²	48	77.8 Å²	77.8	26%	0.257	39%	0.391	S	S	.	.			trans	-111.6	104.8	179.2	-179.3	12.6	0	0	0	111.1	S503 K509 W510	S503-D507 PolarHBondContact O-N 3.44Å; D507-K509 PolarHBondContact O-N 3.02Å; D507-K509 WeakPolarHBondContact OD1-CA 3.33Å; D507-K509 WeakPolarHBondContact OD1-CB 3.43Å; D507-K509 PolarHBondContact OD1-N 3.39Å; D507-W510 HydrophobicContact CB-CB 4.44Å; D507-W510 VanDerWaalsContact O-CB 3.3Å; D507-W510 WeakPolarHBondContact O-CB 3.45Å; D507-W510 PolarHBondContact O-N 2.86Å; D507-W510 PolarHBondContact OD2-N 3.19Å
508	P	90.6	Very high	90.5	Very high	104 Å²	104	76.4 Å²	76.4	68%	0.675	38%	0.376	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.3	-13.2	176.3	27.6	-34.9	0	0	0	113.1	F511	P508-F511 WeakPolarHBondContact O-CE1 3.4Å
509	K	92.2	Very high	90.8	Very high	128 Å²	128	75 Å²	75	56%	0.557	38%	0.375	S	S	*	.	T	Hydrogen-bonded Turn	trans	-103.1	19.9	175.6	-60.2	-179.8	-177.4	176	0	112.6	D507 F511 H512	D507-K509 PolarHBondContact O-N 3.02Å; D507-K509 WeakPolarHBondContact OD1-CA 3.33Å; D507-K509 WeakPolarHBondContact OD1-CB 3.43Å; D507-K509 PolarHBondContact OD1-N 3.39Å; K509-F511 PolarHBondContact O-N 3.48Å; K509-H512 HydrophobicContact CB-CB 4.35Å; K509-H512 WeakPolarHBondContact O-CB 3.48Å; K509-H512 PolarHBondContact O-N 2.9Å
510	W	92.6	Very high	91.1	Very high	77 Å²	77	74.9 Å²	74.9	29%	0.292	38%	0.376	S	S	.	.	T	Hydrogen-bonded Turn	trans	-52.9	-24.6	179.7	68.4	-96.2	0	0	0	114.2	I504 D507 S517 L518 L519	I504-W510 HydrophobicContact CB-CG 4.43Å; I504-W510 HydrophobicContact CG1-CD2 3.81Å; I504-W510 HydrophobicContact CG1-CE3 4.17Å; I504-W510 HydrophobicContact CG1-CG 4.09Å; I504-W510 HydrophobicContact CG1-CZ2 4.35Å; D507-W510 HydrophobicContact CB-CB 4.44Å; D507-W510 VanDerWaalsContact O-CB 3.3Å; D507-W510 WeakPolarHBondContact O-CB 3.45Å; D507-W510 PolarHBondContact O-N 2.86Å; D507-W510 PolarHBondContact OD2-N 3.19Å; W510-S517 WeakPolarHBondContact O-CB 3.3Å; W510-L518 HydrophobicContact CB-CB 4.31Å; W510-L518 HydrophobicContact CE3-CB 4.28Å; W510-L518 HydrophobicContact CE3-CD2 4.01Å; W510-L518 HydrophobicContact CE3-CG 4.42Å; W510-L518 HydrophobicContact CZ3-CD2 4.45Å; W510-L518 PolarHBondContact O-N 2.81Å; W510-L519 WeakPolarHBondContact O-CB 3.29Å; W510-L519 PolarHBondContact O-N 3.1Å
511	F	93.6	Very high	91.3	Very high	103 Å²	103	72 Å²	72	45%	0.452	36%	0.363	S	S	.	.	T	Hydrogen-bonded Turn	trans	-94.6	-1.5	178.7	63.4	-92.9	0	0	0	114.3	P508 K509 L519	P508-F511 WeakPolarHBondContact O-CE1 3.4Å; K509-F511 PolarHBondContact O-N 3.48Å; F511-L519 WeakPolarHBondContact O-CD2 3.38Å
512	H	93	Very high	91.5	Very high	95 Å²	95	68.4 Å²	68.4	44%	0.44	35%	0.352	S	S	.	.	S	Bend	trans	-83.5	143	170.7	-76.5	-92.9	0	0	0	109.8	K509 N514 S517	K509-H512 HydrophobicContact CB-CB 4.35Å; K509-H512 WeakPolarHBondContact O-CB 3.48Å; K509-H512 PolarHBondContact O-N 2.9Å; H512-N514 PolarHBondContact O-N 2.9Å; H512-S517 VanDerWaalsContact O-CB 3.24Å; H512-S517 WeakPolarHBondContact O-CB 3.44Å; H512-S517 PolarHBondContact O-OG 3.24Å
513	L	90.7	Very high	91.8	Very high	124 Å²	124	68.8 Å²	68.8	65%	0.649	36%	0.356	S	S	*	.			trans	-70.7	100.7	173.1	-65.7	174.3	0	0	0	109.5	L519 L523	L513-L519 HydrophobicContact CD2-CD2 3.94Å; L513-L519 HydrophobicContact CD2-CG 4.13Å; L513-L519 HydrophobicContact CG-CD2 4.37Å; L513-L523 HydrophobicContact CD2-CD2 3.93Å
514	N	88	Confident	92.2	Very high	50 Å²	50	69.4 Å²	69.4	27%	0.267	36%	0.356	S	S	.	.			trans	-142.9	162.7	170.8	69.6	61.3	0	0	0	109.2	H512 T516 S517 T520	H512-N514 PolarHBondContact O-N 2.9Å; N514-T516 PolarHBondContact O-N 3.06Å; N514-T516 VanDerWaalsContact O-N 3.12Å; N514-T516 PolarHBondContact OD1-N 3.36Å; N514-T516 VanDerWaalsContact OD1-N 3.09Å; N514-T516 PolarHBondContact OD1-OG1 2.86Å; N514-S517 PolarHBondContact O-N 3.13Å; N514-S517 PolarHBondContact O-OG 2.85Å; N514-S517 WeakPolarHBondContact OD1-CB 3.05Å; N514-S517 PolarHBondContact OD1-N 3.24Å; N514-T520 PolarHBondContact N-OG1 3.32Å; N514-T520 VanDerWaalsContact O-CB 3.25Å; N514-T520 WeakPolarHBondContact O-CB 3.23Å; N514-T520 PolarHBondContact O-OG1 3.16Å
515	W	84.1	Confident	92.3	Very high	113 Å²	113	67.1 Å²	67.1	43%	0.428	34%	0.343	S	S	.	.	T	Hydrogen-bonded Turn	trans	-60.4	-27.1	-171.9	-60.7	113.3	0	0	0	114	Y427 D429 F430 N433	Y427-W515 AromaticContact CE1-CD1 3.67Å; Y427-W515 HydrophobicContact CE1-CD2 4.46Å; Y427-W515 AromaticContact CE1-CE2 3.94Å; Y427-W515 HydrophobicContact CE1-CG 4.31Å; Y427-W515 AromaticContact CE1-NE1 3.45Å; D429-W515 HydrophobicContact CB-CB 4.22Å; D429-W515 HydrophobicContact CB-CG 4.38Å; F430-W515 AromaticContact CD2-CE3 3.89Å; F430-W515 HydrophobicContact CD2-CE3 3.89Å; F430-W515 AromaticContact CD2-CH2 3.76Å; F430-W515 HydrophobicContact CD2-CH2 3.76Å; F430-W515 AromaticContact CD2-CZ3 3.36Å; F430-W515 HydrophobicContact CD2-CZ3 3.36Å; F430-W515 HydrophobicContact CE2-CH2 4.23Å; F430-W515 AromaticContact CE2-CZ3 3.77Å; F430-W515 HydrophobicContact CE2-CZ3 3.77Å; N433-W515 HydrophobicContact CB-CB 4.25Å; N433-W515 WeakPolarHBondContact CB-O 3.29Å; N433-W515 VanDerWaalsContact CG-O 3.3Å; N433-W515 PolarHBondContact ND2-O 3.22Å
516	T	81.5	Confident	92.5	Very high	91 Å²	91	69.2 Å²	69.2	56%	0.558	35%	0.345	S	S	*	.	T	Hydrogen-bonded Turn	trans	-104.8	-0.3	-175.1	53.3	0	0	0	0	114	N514	N514-T516 PolarHBondContact O-N 3.06Å; N514-T516 VanDerWaalsContact O-N 3.12Å; N514-T516 PolarHBondContact OD1-N 3.36Å; N514-T516 VanDerWaalsContact OD1-N 3.09Å; N514-T516 PolarHBondContact OD1-OG1 2.86Å
517	S	91.1	Very high	92.9	Very high	1 Å²	1	68.6 Å²	68.6	1%	0.007	34%	0.341	C	S	.	.			trans	-80.8	152.9	-172.3	71.5	0	0	0	0	113.3	W510 H512 N514 L519 T520 T521	W510-S517 WeakPolarHBondContact O-CB 3.3Å; H512-S517 VanDerWaalsContact O-CB 3.24Å; H512-S517 WeakPolarHBondContact O-CB 3.44Å; H512-S517 PolarHBondContact O-OG 3.24Å; N514-S517 PolarHBondContact O-N 3.13Å; N514-S517 PolarHBondContact O-OG 2.85Å; N514-S517 WeakPolarHBondContact OD1-CB 3.05Å; N514-S517 PolarHBondContact OD1-N 3.24Å; S517-L519 VanDerWaalsContact C-N 3.31Å; S517-L519 PolarHBondContact O-N 3.45Å; S517-T520 PolarHBondContact O-N 3.39Å; S517-T520 PolarHBondContact OG-N 3.38Å; S517-T520 PolarHBondContact OG-OG1 2.99Å; S517-T521 PolarHBondContact O-N 3.48Å
518	L	93.7	Very high	93.2	Very high	7 Å²	7	67 Å²	67	4%	0.037	34%	0.335	C	S	.	.	H	α-helix	trans	-58.2	-43.5	174.5	176.4	60.8	0	0	0	111.4	W499 M500 I504 W510 T520 T521 L522	W499-L518 HydrophobicContact CH2-CD1 3.44Å; W499-L518 VanDerWaalsContact CH2-CD1 3.44Å; W499-L518 HydrophobicContact CZ2-CD1 3.73Å; W499-L518 HydrophobicContact CZ3-CD1 3.92Å; M500-L518 HydrophobicContact CB-CD2 4.36Å; M500-L518 HydrophobicContact CG-CD1 4.03Å; M500-L518 HydrophobicContact CG-CD2 4.42Å; I504-L518 HydrophobicContact CD1-CD2 4Å; I504-L518 HydrophobicContact CG1-CD2 3.69Å; W510-L518 HydrophobicContact CB-CB 4.31Å; W510-L518 HydrophobicContact CE3-CB 4.28Å; W510-L518 HydrophobicContact CE3-CD2 4.01Å; W510-L518 HydrophobicContact CE3-CG 4.42Å; W510-L518 HydrophobicContact CZ3-CD2 4.45Å; W510-L518 PolarHBondContact O-N 2.81Å; L518-T520 VanDerWaalsContact C-N 3.31Å; L518-T520 PolarHBondContact O-N 2.88Å; L518-T521 PolarHBondContact O-N 3.23Å; L518-L522 HydrophobicContact CD1-CD1 4.14Å; L518-L522 HydrophobicContact CD1-CD2 4.46Å; L518-L522 HydrophobicContact CD1-CG 4.04Å; L518-L522 HydrophobicContact CD2-CD1 4.49Å; L518-L522 HydrophobicContact CG-CD1 3.94Å; L518-L522 HydrophobicContact CG-CG 4.27Å; L518-L522 WeakPolarHBondContact O-CG 3.5Å; L518-L522 PolarHBondContact O-N 3.27Å
519	L	96.1	Very high	93.6	Very high	61 Å²	61	64.4 Å²	64.4	32%	0.319	32%	0.315	S	S	.	.	H	α-helix	trans	-60.4	-40.7	-179.5	178.6	65.1	0	0	0	112.3	W510 F511 L513 S517 T521 L522 L523	W510-L519 WeakPolarHBondContact O-CB 3.29Å; W510-L519 PolarHBondContact O-N 3.1Å; F511-L519 WeakPolarHBondContact O-CD2 3.38Å; L513-L519 HydrophobicContact CD2-CD2 3.94Å; L513-L519 HydrophobicContact CD2-CG 4.13Å; L513-L519 HydrophobicContact CG-CD2 4.37Å; S517-L519 VanDerWaalsContact C-N 3.31Å; S517-L519 PolarHBondContact O-N 3.45Å; L519-T521 PolarHBondContact O-N 2.89Å; L519-L522 PolarHBondContact O-N 3.06Å; L519-L523 VanDerWaalsContact O-CB 3.3Å; L519-L523 WeakPolarHBondContact O-CB 3.5Å; L519-L523 PolarHBondContact O-N 2.87Å
520	T	95.4	Very high	93.9	Very high	18 Å²	18	61.7 Å²	61.7	11%	0.11	31%	0.306	C	S	.	.	H	α-helix	trans	-60.7	-46.9	178.3	-60.6	0	0	0	0	110.8	N514 S517 L518 L522 L523 E524	N514-T520 PolarHBondContact N-OG1 3.32Å; N514-T520 VanDerWaalsContact O-CB 3.25Å; N514-T520 WeakPolarHBondContact O-CB 3.23Å; N514-T520 PolarHBondContact O-OG1 3.16Å; S517-T520 PolarHBondContact O-N 3.39Å; S517-T520 PolarHBondContact OG-N 3.38Å; S517-T520 PolarHBondContact OG-OG1 2.99Å; L518-T520 VanDerWaalsContact C-N 3.31Å; L518-T520 PolarHBondContact O-N 2.88Å; T520-L522 PolarHBondContact O-N 3.5Å; T520-L523 PolarHBondContact O-N 3.38Å; T520-E524 WeakPolarHBondContact CG2-OE1 3.39Å; T520-E524 WeakPolarHBondContact O-CG 3.23Å; T520-E524 PolarHBondContact O-N 3.21Å
521	T	95.3	Very high	94.2	Very high	6 Å²	6	59.8 Å²	59.8	4%	0.037	31%	0.311	C	S	.	.	H	α-helix	trans	-59	-46.5	175.5	-66.6	0	0	0	0	112	T437 W499 S517 L518 L519 L523 E524 W525	T437-T521 HydrophobicContact CG2-CG2 4Å; T437-T521 PolarHBondContact OG1-OG1 2.84Å; W499-T521 HydrophobicContact CH2-CG2 3.57Å; W499-T521 HydrophobicContact CZ2-CG2 4.11Å; S517-T521 PolarHBondContact O-N 3.48Å; L518-T521 PolarHBondContact O-N 3.23Å; L519-T521 PolarHBondContact O-N 2.89Å; T521-L523 VanDerWaalsContact C-N 3.32Å; T521-L523 PolarHBondContact O-N 3.29Å; T521-E524 PolarHBondContact O-N 3.31Å; T521-W525 HydrophobicContact CG2-CD2 4.25Å; T521-W525 HydrophobicContact CG2-CH2 4.36Å; T521-W525 HydrophobicContact CG2-CZ2 3.87Å; T521-W525 PolarHBondContact O-N 3.49Å
522	L	96.3	Very high	94.4	Very high	60 Å²	60	55.4 Å²	55.4	31%	0.314	29%	0.292	S	S	.	.	H	α-helix	trans	-64.5	-37	178.9	-67.2	177.8	0	0	0	112.2	L518 L519 T520 W525 F526	L518-L522 HydrophobicContact CD1-CD1 4.14Å; L518-L522 HydrophobicContact CD1-CD2 4.46Å; L518-L522 HydrophobicContact CD1-CG 4.04Å; L518-L522 HydrophobicContact CD2-CD1 4.49Å; L518-L522 HydrophobicContact CG-CD1 3.94Å; L518-L522 HydrophobicContact CG-CG 4.27Å; L518-L522 WeakPolarHBondContact O-CG 3.5Å; L518-L522 PolarHBondContact O-N 3.27Å; L519-L522 PolarHBondContact O-N 3.06Å; T520-L522 PolarHBondContact O-N 3.5Å; L522-W525 HydrophobicContact CD2-CE3 4.02Å; L522-W525 HydrophobicContact CD2-CZ3 4.15Å; L522-F526 VanDerWaalsContact O-CB 3.3Å; L522-F526 WeakPolarHBondContact O-CB 3.49Å; L522-F526 PolarHBondContact O-N 2.88Å
523	L	96.6	Very high	94.6	Very high	79 Å²	79	55.4 Å²	55.4	41%	0.414	29%	0.291	S	S	.	.	H	α-helix	trans	-68.1	-42.9	177.1	-176.5	63.5	0	0	0	111.3	L513 L519 T520 T521 W525 F526 V527	L513-L523 HydrophobicContact CD2-CD2 3.93Å; L519-L523 VanDerWaalsContact O-CB 3.3Å; L519-L523 WeakPolarHBondContact O-CB 3.5Å; L519-L523 PolarHBondContact O-N 2.87Å; T520-L523 PolarHBondContact O-N 3.38Å; T521-L523 VanDerWaalsContact C-N 3.32Å; T521-L523 PolarHBondContact O-N 3.29Å; L523-W525 VanDerWaalsContact C-N 3.35Å; L523-W525 PolarHBondContact O-N 2.64Å; L523-F526 WeakPolarHBondContact O-CB 3.46Å; L523-F526 PolarHBondContact O-N 3.12Å; L523-V527 HydrophobicContact CD1-CG2 4.49Å; L523-V527 VanDerWaalsContact O-CG2 3.3Å; L523-V527 WeakPolarHBondContact O-CG2 3.46Å; L523-V527 PolarHBondContact O-N 3.17Å
524	E	96.8	Very high	94.9	Very high	39 Å²	39	54 Å²	54	18%	0.182	28%	0.283	C	S	.	.	H	α-helix	trans	-59.2	-45.5	174.7	-73.6	-180	-121.4	0	0	111.5	N433 Q434 T437 T520 T521 F526 V527 A528	N433-E524 PolarHBondContact ND2-OE1 3.33Å; N433-E524 PolarHBondContact OD1-OE1 3.45Å; Q434-E524 PolarHBondContact NE2-OE2 2.89Å; T437-E524 HydrophobicContact CG2-CB 3.98Å; T520-E524 WeakPolarHBondContact CG2-OE1 3.39Å; T520-E524 WeakPolarHBondContact O-CG 3.23Å; T520-E524 PolarHBondContact O-N 3.21Å; T521-E524 PolarHBondContact O-N 3.31Å; E524-F526 PolarHBondContact O-N 3.48Å; E524-V527 PolarHBondContact O-N 3.11Å; E524-A528 WeakPolarHBondContact O-CB 3.28Å; E524-A528 PolarHBondContact O-N 2.89Å
525	W	97.6	Very high	95.3	Very high	23 Å²	23	55 Å²	55	9%	0.087	29%	0.288	C	S	.	.	H	α-helix	trans	-62	-43.1	174	-69.4	-3.2	0	0	0	112.5	W143 T437 I444 L496 W499 T521 L522 L523 A528 L529	W143-W525 HydrophobicContact CH2-CB 4.12Å; W143-W525 AromaticContact CH2-CD1 3.89Å; W143-W525 HydrophobicContact CH2-CD2 4.19Å; W143-W525 AromaticContact CH2-CG 3.8Å; W143-W525 HydrophobicContact CH2-CG 3.8Å; W143-W525 HydrophobicContact CZ3-CB 4.48Å; T437-W525 WeakPolarHBondContact O-CZ2 3.39Å; T437-W525 PolarHBondContact O-NE1 3.26Å; I444-W525 HydrophobicContact CD1-CD2 4.4Å; I444-W525 HydrophobicContact CD1-CE3 3.97Å; I444-W525 HydrophobicContact CD1-CH2 3.88Å; I444-W525 HydrophobicContact CD1-CZ2 4.3Å; I444-W525 HydrophobicContact CD1-CZ3 3.71Å; L496-W525 HydrophobicContact CD2-CH2 4.25Å; W499-W525 HydrophobicContact CH2-CH2 4.12Å; W499-W525 AromaticContact CZ3-CH2 3.73Å; W499-W525 HydrophobicContact CZ3-CH2 3.73Å; W499-W525 HydrophobicContact CZ3-CZ3 4.17Å; T521-W525 HydrophobicContact CG2-CD2 4.25Å; T521-W525 HydrophobicContact CG2-CH2 4.36Å; T521-W525 HydrophobicContact CG2-CZ2 3.87Å; T521-W525 PolarHBondContact O-N 3.49Å; L522-W525 HydrophobicContact CD2-CE3 4.02Å; L522-W525 HydrophobicContact CD2-CZ3 4.15Å; L523-W525 VanDerWaalsContact C-N 3.35Å; L523-W525 PolarHBondContact O-N 2.64Å; W525-A528 PolarHBondContact O-N 2.98Å; W525-L529 WeakPolarHBondContact O-CB 3.27Å; W525-L529 VanDerWaalsContact O-CG 3.3Å; W525-L529 WeakPolarHBondContact O-CG 3.21Å; W525-L529 PolarHBondContact O-N 3.27Å
526	F	97.6	Very high	95.9	Very high	122 Å²	122	50.4 Å²	50.4	54%	0.535	27%	0.272	S	S	.	.	H	α-helix	trans	-61.6	-45.1	178.1	-179.3	-107.7	0	0	0	111.8	L522 L523 E524 L529 I530	L522-F526 VanDerWaalsContact O-CB 3.3Å; L522-F526 WeakPolarHBondContact O-CB 3.49Å; L522-F526 PolarHBondContact O-N 2.88Å; L523-F526 WeakPolarHBondContact O-CB 3.46Å; L523-F526 PolarHBondContact O-N 3.12Å; E524-F526 PolarHBondContact O-N 3.48Å; F526-L529 PolarHBondContact O-N 3.25Å; F526-I530 HydrophobicContact CD1-CD1 3.78Å; F526-I530 HydrophobicContact CE1-CD1 3.28Å; F526-I530 HydrophobicContact CE1-CG1 4.36Å; F526-I530 HydrophobicContact CE2-CD1 4.16Å; F526-I530 HydrophobicContact CG-CD1 4.42Å; F526-I530 HydrophobicContact CZ-CD1 3.5Å; F526-I530 HydrophobicContact CZ-CG1 4.3Å; F526-I530 WeakPolarHBondContact O-CG1 3.29Å; F526-I530 PolarHBondContact O-N 3.05Å
527	V	97.8	Very high	96.6	Very high	91 Å²	91	53.7 Å²	53.7	55%	0.552	27%	0.274	S	S	*	.	H	α-helix	trans	-61.6	-45.3	175.4	171.1	0	0	0	0	110.8	L523 E524 L529 I530 G531	L523-V527 HydrophobicContact CD1-CG2 4.49Å; L523-V527 VanDerWaalsContact O-CG2 3.3Å; L523-V527 WeakPolarHBondContact O-CG2 3.46Å; L523-V527 PolarHBondContact O-N 3.17Å; E524-V527 PolarHBondContact O-N 3.11Å; V527-L529 PolarHBondContact O-N 3.16Å; V527-I530 PolarHBondContact O-N 3.15Å; V527-G531 PolarHBondContact O-N 3.46Å
528	A	97.9	Very high	96.9	Very high	16 Å²	16	57.2 Å²	57.2	13%	0.132	29%	0.292	C	S	.	.	H	α-helix	trans	-61.2	-43.5	176.8	0	0	0	0	0	112	T146 W438 E524 W525 G531 L532	T146-A528 HydrophobicContact CG2-CB 4.36Å; W438-A528 HydrophobicContact CH2-CB 3.95Å; E524-A528 WeakPolarHBondContact O-CB 3.28Å; E524-A528 PolarHBondContact O-N 2.89Å; W525-A528 PolarHBondContact O-N 2.98Å; A528-G531 PolarHBondContact O-N 3.12Å; A528-L532 WeakPolarHBondContact O-CB 3.45Å; A528-L532 VanDerWaalsContact O-CG 3.28Å; A528-L532 WeakPolarHBondContact O-CG 3.11Å; A528-L532 PolarHBondContact O-N 2.86Å
529	L	98.2	Very high	97	Very high	49 Å²	49	57.4 Å²	57.4	26%	0.257	29%	0.293	S	S	.	.	H	α-helix	trans	-64.1	-42.9	177.3	-74.8	170.6	0	0	0	112.4	W139 W143 W525 F526 V527 G531 L532 F533	W139-L529 HydrophobicContact CE3-CD2 4.31Å; W139-L529 HydrophobicContact CZ3-CD2 4.07Å; W143-L529 HydrophobicContact CE3-CD2 3.71Å; W143-L529 HydrophobicContact CE3-CG 4.18Å; W143-L529 HydrophobicContact CZ3-CD1 4.5Å; W143-L529 HydrophobicContact CZ3-CD2 3.95Å; W143-L529 HydrophobicContact CZ3-CG 3.9Å; W525-L529 WeakPolarHBondContact O-CB 3.27Å; W525-L529 VanDerWaalsContact O-CG 3.3Å; W525-L529 WeakPolarHBondContact O-CG 3.21Å; W525-L529 PolarHBondContact O-N 3.27Å; F526-L529 PolarHBondContact O-N 3.25Å; V527-L529 PolarHBondContact O-N 3.16Å; L529-G531 VanDerWaalsContact C-N 3.33Å; L529-G531 PolarHBondContact O-N 3.15Å; L529-L532 PolarHBondContact O-N 3.28Å; L529-F533 HydrophobicContact CB-CE2 4.26Å; L529-F533 WeakPolarHBondContact O-CD2 3.48Å; L529-F533 VanDerWaalsContact O-CG 3.32Å; L529-F533 WeakPolarHBondContact O-CG 3.46Å; L529-F533 PolarHBondContact O-N 3.09Å
530	I	98.2	Very high	96.8	Very high	70 Å²	70	58.9 Å²	58.9	36%	0.359	30%	0.295	S	S	.	.	H	α-helix	trans	-58	-48.6	173.2	-72.5	172.5	0	0	0	110.2	F526 V527 L532 F533 I534	F526-I530 HydrophobicContact CD1-CD1 3.78Å; F526-I530 HydrophobicContact CE1-CD1 3.28Å; F526-I530 HydrophobicContact CE1-CG1 4.36Å; F526-I530 HydrophobicContact CE2-CD1 4.16Å; F526-I530 HydrophobicContact CG-CD1 4.42Å; F526-I530 HydrophobicContact CZ-CD1 3.5Å; F526-I530 HydrophobicContact CZ-CG1 4.3Å; F526-I530 WeakPolarHBondContact O-CG1 3.29Å; F526-I530 PolarHBondContact O-N 3.05Å; V527-I530 PolarHBondContact O-N 3.15Å; I530-L532 VanDerWaalsContact C-N 3.3Å; I530-L532 PolarHBondContact O-N 2.82Å; I530-F533 PolarHBondContact O-N 3.41Å; I530-I534 HydrophobicContact CG2-CD1 3.71Å; I530-I534 HydrophobicContact CG2-CG1 4.4Å; I530-I534 WeakPolarHBondContact O-CG1 3.4Å; I530-I534 PolarHBondContact O-N 2.96Å
531	G	98	Very high	96.7	Very high	38 Å²	38	66.4 Å²	66.4	39%	0.392	32%	0.322	S	S	.	.	H	α-helix	trans	-56.9	-44	177.3	0	0	0	0	0	112.2	V527 A528 L529 I534 L535	V527-G531 PolarHBondContact O-N 3.46Å; A528-G531 PolarHBondContact O-N 3.12Å; L529-G531 VanDerWaalsContact C-N 3.33Å; L529-G531 PolarHBondContact O-N 3.15Å; G531-I534 PolarHBondContact O-N 3.14Å; G531-L535 VanDerWaalsContact O-CB 3.3Å; G531-L535 WeakPolarHBondContact O-CB 3.42Å; G531-L535 PolarHBondContact O-N 3.49Å
532	L	98.1	Very high	96.6	Very high	10 Å²	10	69.5 Å²	69.5	5%	0.052	34%	0.34	C	S	.	.	H	α-helix	trans	-67	-37.9	177.4	-72.8	175.4	0	0	0	113.1	W139 A142 W143 A528 L529 I530 L535 N536	W139-L532 HydrophobicContact CB-CB 4.23Å; A142-L532 HydrophobicContact CB-CD2 3.68Å; W143-L532 HydrophobicContact CB-CD1 4.11Å; W143-L532 HydrophobicContact CE3-CD1 4.25Å; A528-L532 WeakPolarHBondContact O-CB 3.45Å; A528-L532 VanDerWaalsContact O-CG 3.28Å; A528-L532 WeakPolarHBondContact O-CG 3.11Å; A528-L532 PolarHBondContact O-N 2.86Å; L529-L532 PolarHBondContact O-N 3.28Å; I530-L532 VanDerWaalsContact C-N 3.3Å; I530-L532 PolarHBondContact O-N 2.82Å; L532-L535 HydrophobicContact CD2-CD2 4.46Å; L532-L535 PolarHBondContact O-N 2.86Å; L532-N536 WeakPolarHBondContact O-CB 3.42Å; L532-N536 PolarHBondContact O-N 3.27Å
533	F	98	Very high	96.3	Very high	95 Å²	95	71.3 Å²	71.3	42%	0.417	35%	0.351	S	S	.	.	H	α-helix	trans	-67.1	-41.9	175	-69.3	-41.5	0	0	0	112	W139 L529 I530 N536 W537	W139-F533 HydrophobicContact CD2-CD1 4.23Å; W139-F533 AromaticContact CD2-CE1 3.59Å; W139-F533 HydrophobicContact CD2-CE1 3.59Å; W139-F533 HydrophobicContact CD2-CZ 4.47Å; W139-F533 AromaticContact CE2-CE1 3.59Å; W139-F533 AromaticContact CE3-CE1 3.99Å; W139-F533 HydrophobicContact CE3-CE1 3.99Å; W139-F533 HydrophobicContact CE3-CZ 4.49Å; W139-F533 HydrophobicContact CG-CD1 4.09Å; W139-F533 AromaticContact CG-CE1 3.93Å; W139-F533 HydrophobicContact CG-CE1 3.93Å; W139-F533 HydrophobicContact CH2-CE1 4.31Å; W139-F533 HydrophobicContact CH2-CZ 4.41Å; W139-F533 AromaticContact CZ2-CE1 3.97Å; W139-F533 HydrophobicContact CZ2-CE1 3.97Å; W139-F533 HydrophobicContact CZ2-CZ 4.41Å; W139-F533 HydrophobicContact CZ3-CE1 4.33Å; W139-F533 HydrophobicContact CZ3-CZ 4.46Å; W139-F533 AromaticContact NE1-CE1 3.87Å; L529-F533 HydrophobicContact CB-CE2 4.26Å; L529-F533 WeakPolarHBondContact O-CD2 3.48Å; L529-F533 VanDerWaalsContact O-CG 3.32Å; L529-F533 WeakPolarHBondContact O-CG 3.46Å; L529-F533 PolarHBondContact O-N 3.09Å; I530-F533 PolarHBondContact O-N 3.41Å; F533-N536 PolarHBondContact O-N 3.31Å; F533-W537 WeakPolarHBondContact O-CB 3.35Å; F533-W537 PolarHBondContact O-N 2.88Å
534	I	97.8	Very high	96	Very high	94 Å²	94	70.1 Å²	70.1	48%	0.482	34%	0.344	S	S	.	.	H	α-helix	trans	-62.7	-48.3	174.4	-66.8	169	0	0	0	109.9	I530 G531 N536 W537 I538	I530-I534 HydrophobicContact CG2-CD1 3.71Å; I530-I534 HydrophobicContact CG2-CG1 4.4Å; I530-I534 WeakPolarHBondContact O-CG1 3.4Å; I530-I534 PolarHBondContact O-N 2.96Å; G531-I534 PolarHBondContact O-N 3.14Å; I534-N536 PolarHBondContact O-N 3.07Å; I534-W537 PolarHBondContact O-N 2.8Å; I534-I538 HydrophobicContact CG2-CD1 3.85Å; I534-I538 HydrophobicContact CG2-CG1 4.47Å; I534-I538 VanDerWaalsContact O-CG1 3.32Å; I534-I538 WeakPolarHBondContact O-CG1 3.3Å; I534-I538 PolarHBondContact O-N 3.03Å
535	L	96.4	Very high	95.7	Very high	73 Å²	73	68.3 Å²	68.3	38%	0.382	34%	0.335	S	S	.	.	H	α-helix	trans	-57.4	-49.9	177.4	176.7	63.7	0	0	0	111.2	G531 L532 W537 I538 L539	G531-L535 VanDerWaalsContact O-CB 3.3Å; G531-L535 WeakPolarHBondContact O-CB 3.42Å; G531-L535 PolarHBondContact O-N 3.49Å; L532-L535 HydrophobicContact CD2-CD2 4.46Å; L532-L535 PolarHBondContact O-N 2.86Å; L535-W537 VanDerWaalsContact C-N 3.32Å; L535-W537 PolarHBondContact O-N 3.42Å; L535-I538 PolarHBondContact O-N 2.98Å; L535-L539 HydrophobicContact CD1-CD1 3.95Å; L535-L539 HydrophobicContact CD1-CG 4.01Å; L535-L539 HydrophobicContact CG-CD1 3.89Å; L535-L539 HydrophobicContact CG-CG 4.31Å; L535-L539 WeakPolarHBondContact O-CB 3.3Å; L535-L539 VanDerWaalsContact O-CG 3.29Å; L535-L539 WeakPolarHBondContact O-CG 3.42Å; L535-L539 PolarHBondContact O-N 3.47Å
536	N	96.9	Very high	95.3	Very high	16 Å²	16	68.8 Å²	68.8	9%	0.086	34%	0.343	C	S	.	.	H	α-helix	trans	-59.4	-42.5	178.1	-179.2	59.6	0	0	0	111.7	Q135 K136 F138 W139 L532 F533 I534 L539 Y540	Q135-N536 PolarHBondContact O-OD1 3.47Å; K136-N536 PolarHBondContact O-ND2 3.37Å; F138-N536 VanDerWaalsContact CB-OD1 3.26Å; F138-N536 WeakPolarHBondContact CB-OD1 3.5Å; W139-N536 HydrophobicContact CB-CB 4.17Å; L532-N536 WeakPolarHBondContact O-CB 3.42Å; L532-N536 PolarHBondContact O-N 3.27Å; F533-N536 PolarHBondContact O-N 3.31Å; I534-N536 PolarHBondContact O-N 3.07Å; N536-L539 PolarHBondContact O-N 2.95Å; N536-Y540 WeakPolarHBondContact O-CB 3.49Å; N536-Y540 PolarHBondContact O-N 3.22Å
537	W	96.2	Very high	94.9	Very high	159 Å²	159	68.9 Å²	68.9	60%	0.602	34%	0.343	S	S	*	.	H	α-helix	trans	-61.5	-44.8	175.4	179.2	81.4	0	0	0	112.1	F533 I534 L535 R541	F533-W537 WeakPolarHBondContact O-CB 3.35Å; F533-W537 PolarHBondContact O-N 2.88Å; I534-W537 PolarHBondContact O-N 2.8Å; L535-W537 VanDerWaalsContact C-N 3.32Å; L535-W537 PolarHBondContact O-N 3.42Å; W537-R541 HydrophobicContact CD2-CG 4.3Å; W537-R541 HydrophobicContact CG-CG 4.49Å; W537-R541 HydrophobicContact CZ2-CG 4.34Å; W537-R541 WeakPolarHBondContact O-CB 3.48Å; W537-R541 VanDerWaalsContact O-CG 3.23Å; W537-R541 WeakPolarHBondContact O-CG 3.31Å; W537-R541 PolarHBondContact O-N 2.84Å
538	I	96.4	Very high	94.4	Very high	75 Å²	75	64.8 Å²	64.8	39%	0.385	32%	0.318	S	S	.	.	H	α-helix	trans	-62.2	-50.8	176.3	-66.4	168.2	0	0	0	110.6	I534 L535 Y540 R541 T542	I534-I538 HydrophobicContact CG2-CD1 3.85Å; I534-I538 HydrophobicContact CG2-CG1 4.47Å; I534-I538 VanDerWaalsContact O-CG1 3.32Å; I534-I538 WeakPolarHBondContact O-CG1 3.3Å; I534-I538 PolarHBondContact O-N 3.03Å; L535-I538 PolarHBondContact O-N 2.98Å; I538-Y540 VanDerWaalsContact C-N 3.28Å; I538-Y540 PolarHBondContact O-N 3.48Å; I538-R541 PolarHBondContact O-N 3.44Å; I538-T542 HydrophobicContact CG2-CG2 4.21Å; I538-T542 WeakPolarHBondContact O-CB 3.3Å; I538-T542 VanDerWaalsContact O-CG2 3.29Å; I538-T542 WeakPolarHBondContact O-CG2 2.97Å; I538-T542 PolarHBondContact O-N 3.3Å; I538-T542 PolarHBondContact O-OG1 3.28Å
539	L	94.9	Very high	93.9	Very high	12 Å²	12	65.8 Å²	65.8	6%	0.063	32%	0.321	C	S	.	.	H	α-helix	trans	-62.5	-36.1	-178	-69.2	178.1	0	0	0	112.4	F138 L402 L535 N536 T542 I544 L545	F138-L539 HydrophobicContact CD1-CD1 4.06Å; F138-L539 HydrophobicContact CE1-CD1 3.7Å; F138-L539 HydrophobicContact CZ-CD1 4.13Å; L402-L539 HydrophobicContact CD1-CD1 4.32Å; L402-L539 HydrophobicContact CD2-CD1 4.35Å; L402-L539 HydrophobicContact CD2-CD2 4.37Å; L535-L539 HydrophobicContact CD1-CD1 3.95Å; L535-L539 HydrophobicContact CD1-CG 4.01Å; L535-L539 HydrophobicContact CG-CD1 3.89Å; L535-L539 HydrophobicContact CG-CG 4.31Å; L535-L539 WeakPolarHBondContact O-CB 3.3Å; L535-L539 VanDerWaalsContact O-CG 3.29Å; L535-L539 WeakPolarHBondContact O-CG 3.42Å; L535-L539 PolarHBondContact O-N 3.47Å; N536-L539 PolarHBondContact O-N 2.95Å; L539-T542 PolarHBondContact O-OG1 3.09Å; L539-I544 HydrophobicContact CD2-CB 4.14Å; L539-I544 HydrophobicContact CD2-CD1 4.1Å; L539-I544 HydrophobicContact CD2-CG2 3.96Å; L539-I544 PolarHBondContact O-N 3.21Å; L539-L545 PolarHBondContact O-N 3.33Å
540	Y	92.6	Very high	93.3	Very high	92 Å²	92	69.8 Å²	69.8	36%	0.361	34%	0.343	S	S	.	.	H	α-helix	trans	-68.4	-49	174.2	-178.1	-100.5	0	0	0	111.6	Q135 K136 N536 I538 T542 N543	Q135-Y540 HydrophobicContact CB-CD2 3.84Å; Q135-Y540 HydrophobicContact CB-CE2 4.03Å; K136-Y540 HydrophobicContact CG-CE2 4.16Å; N536-Y540 WeakPolarHBondContact O-CB 3.49Å; N536-Y540 PolarHBondContact O-N 3.22Å; I538-Y540 VanDerWaalsContact C-N 3.28Å; I538-Y540 PolarHBondContact O-N 3.48Å; Y540-T542 VanDerWaalsContact C-N 3.32Å; Y540-T542 PolarHBondContact O-N 3.05Å; Y540-N543 PolarHBondContact O-N 3.41Å
541	R	93.9	Very high	92.4	Very high	176 Å²	176	72 Å²	72	66%	0.664	35%	0.35	S	S	*	.	H	α-helix	trans	-68.8	-28.8	-177.1	-69.9	-72.4	-91.8	-175.2	-6.4	113.5	W537 I538 N543	W537-R541 HydrophobicContact CD2-CG 4.3Å; W537-R541 HydrophobicContact CG-CG 4.49Å; W537-R541 HydrophobicContact CZ2-CG 4.34Å; W537-R541 WeakPolarHBondContact O-CB 3.48Å; W537-R541 VanDerWaalsContact O-CG 3.23Å; W537-R541 WeakPolarHBondContact O-CG 3.31Å; W537-R541 PolarHBondContact O-N 2.84Å; I538-R541 PolarHBondContact O-N 3.44Å; R541-N543 VanDerWaalsContact C-N 3.3Å
542	T	92.9	Very high	91.4	Very high	70 Å²	70	71.4 Å²	71.4	43%	0.429	34%	0.341	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85.6	2	179	54	0	0	0	0	113.6	I538 L539 Y540 I544	I538-T542 HydrophobicContact CG2-CG2 4.21Å; I538-T542 WeakPolarHBondContact O-CB 3.3Å; I538-T542 VanDerWaalsContact O-CG2 3.29Å; I538-T542 WeakPolarHBondContact O-CG2 2.97Å; I538-T542 PolarHBondContact O-N 3.3Å; I538-T542 PolarHBondContact O-OG1 3.28Å; L539-T542 PolarHBondContact O-OG1 3.09Å; Y540-T542 VanDerWaalsContact C-N 3.32Å; Y540-T542 PolarHBondContact O-N 3.05Å; T542-I544 PolarHBondContact O-N 3.41Å; T542-I544 VanDerWaalsContact OG1-CD1 3.31Å; T542-I544 WeakPolarHBondContact OG1-CD1 3.43Å; T542-I544 WeakPolarHBondContact OG1-CG1 3.33Å
543	N	90.1	Very high	90.5	Very high	99 Å²	99	73.8 Å²	73.8	53%	0.529	35%	0.352	S	S	.	.	T	Hydrogen-bonded Turn	trans	56.2	14.3	-173.8	-72.7	-24.4	0	0	0	114.5	Y540 R541 L545 S546 K547	Y540-N543 PolarHBondContact O-N 3.41Å; R541-N543 VanDerWaalsContact C-N 3.3Å; N543-L545 VanDerWaalsContact C-N 3.29Å; N543-L545 PolarHBondContact O-N 3.44Å; N543-S546 PolarHBondContact O-N 3.48Å; N543-K547 WeakPolarHBondContact O-CG 3.17Å; N543-K547 PolarHBondContact O-N 2.85Å; N543-K547 VanDerWaalsContact O-N 3.09Å
544	I	90.9	Very high	89.9	Confident	54 Å²	54	70.4 Å²	70.4	28%	0.277	34%	0.344	S	S	.	.	H	α-helix	trans	-62.5	-42.2	177.8	-68.1	172.6	0	0	0	109.7	L402 L539 T542 K547 A548	L402-I544 HydrophobicContact CD2-CG2 4.04Å; L539-I544 HydrophobicContact CD2-CB 4.14Å; L539-I544 HydrophobicContact CD2-CD1 4.1Å; L539-I544 HydrophobicContact CD2-CG2 3.96Å; L539-I544 PolarHBondContact O-N 3.21Å; T542-I544 PolarHBondContact O-N 3.41Å; T542-I544 VanDerWaalsContact OG1-CD1 3.31Å; T542-I544 WeakPolarHBondContact OG1-CD1 3.43Å; T542-I544 WeakPolarHBondContact OG1-CG1 3.33Å; I544-K547 WeakPolarHBondContact O-CB 3.47Å; I544-K547 PolarHBondContact O-N 2.91Å; I544-A548 PolarHBondContact O-N 3.23Å
545	L	89.7	Confident	89.5	Confident	0 Å²	0	66 Å²	66	0%	0	32%	0.321	C	S	.	.	H	α-helix	trans	-67.5	-39	-179.2	-176.2	52.6	0	0	0	112.8	Q135 F138 L539 N543 K547 A548 L549	Q135-L545 HydrophobicContact CB-CD2 3.61Å; Q135-L545 HydrophobicContact CB-CG 4.15Å; Q135-L545 HydrophobicContact CG-CD2 3.98Å; Q135-L545 HydrophobicContact CG-CG 3.96Å; Q135-L545 WeakPolarHBondContact O-CD2 3.13Å; F138-L545 HydrophobicContact CB-CD2 3.85Å; F138-L545 HydrophobicContact CD2-CD1 3.62Å; F138-L545 HydrophobicContact CD2-CD2 4.17Å; F138-L545 HydrophobicContact CE2-CD1 4.07Å; F138-L545 HydrophobicContact CG-CD1 4.48Å; F138-L545 HydrophobicContact CG-CD2 4.27Å; L539-L545 PolarHBondContact O-N 3.33Å; N543-L545 VanDerWaalsContact C-N 3.29Å; N543-L545 PolarHBondContact O-N 3.44Å; L545-K547 VanDerWaalsContact C-N 3.32Å; L545-K547 PolarHBondContact O-N 3.24Å; L545-A548 PolarHBondContact O-N 3.41Å; L545-L549 HydrophobicContact CD1-CD1 4.42Å; L545-L549 HydrophobicContact CD1-CG 4.36Å; L545-L549 HydrophobicContact CG-CD1 4.3Å; L545-L549 WeakPolarHBondContact O-CB 3.29Å; L545-L549 WeakPolarHBondContact O-CG 3.47Å; L545-L549 PolarHBondContact O-N 2.87Å
546	S	90	Very high	89.2	Confident	34 Å²	34	65.5 Å²	65.5	24%	0.238	32%	0.319	C	S	.	.	H	α-helix	trans	-61	-42.5	172.3	174.5	0	0	0	0	111.4	N543 L549 N550	N543-S546 PolarHBondContact O-N 3.48Å; S546-L549 PolarHBondContact O-N 2.85Å; S546-N550 WeakPolarHBondContact O-CB 3.28Å; S546-N550 PolarHBondContact O-N 3.25Å; S546-N550 PolarHBondContact O-ND2 2.88Å; S546-N550 PolarHBondContact O-OD1 2.86Å
547	K	88.9	Confident	88.9	Confident	123 Å²	123	64.8 Å²	64.8	54%	0.535	32%	0.315	S	S	.	.	H	α-helix	trans	-64	-40.3	174.8	-70.1	175.5	-179	177.8	0	112.2	N543 I544 L545 N550 K551	N543-K547 WeakPolarHBondContact O-CG 3.17Å; N543-K547 PolarHBondContact O-N 2.85Å; N543-K547 VanDerWaalsContact O-N 3.09Å; I544-K547 WeakPolarHBondContact O-CB 3.47Å; I544-K547 PolarHBondContact O-N 2.91Å; L545-K547 VanDerWaalsContact C-N 3.32Å; L545-K547 PolarHBondContact O-N 3.24Å; K547-N550 PolarHBondContact O-N 2.87Å; K547-K551 WeakPolarHBondContact O-CG 3.16Å; K547-K551 PolarHBondContact O-N 3.47Å; K547-K551 VanDerWaalsContact O-N 3.11Å
548	A	87	Confident	88.6	Confident	5 Å²	5	62.2 Å²	62.2	4%	0.041	31%	0.306	C	S	.	.	H	α-helix	trans	-63.7	-44.1	177.1	0	0	0	0	0	111.6	E401 I544 L545 K551 A552	E401-A548 WeakPolarHBondContact O-CB 3.3Å; I544-A548 PolarHBondContact O-N 3.23Å; L545-A548 PolarHBondContact O-N 3.41Å; A548-K551 CarbonylContact O-C 3.55Å; A548-K551 PolarHBondContact O-N 3.39Å; A548-A552 PolarHBondContact O-N 2.9Å
549	L	87	Confident	88.2	Confident	38 Å²	38	62.5 Å²	62.5	20%	0.199	31%	0.309	C	S	.	.	H	α-helix	trans	-66.3	-38.2	176.3	-75	168.2	0	0	0	112.7	V127 C130 K131 Q135 L545 S546 K551 A552	V127-L549 HydrophobicContact CG1-CD2 3.91Å; C130-L549 HydrophobicContact CB-CD1 4.36Å; C130-L549 HydrophobicContact CB-CD2 4.1Å; K131-L549 HydrophobicContact CG-CD2 4.05Å; Q135-L549 HydrophobicContact CG-CD1 3.46Å; Q135-L549 VanDerWaalsContact CG-CD1 3.46Å; L545-L549 HydrophobicContact CD1-CD1 4.42Å; L545-L549 HydrophobicContact CD1-CG 4.36Å; L545-L549 HydrophobicContact CG-CD1 4.3Å; L545-L549 WeakPolarHBondContact O-CB 3.29Å; L545-L549 WeakPolarHBondContact O-CG 3.47Å; L545-L549 PolarHBondContact O-N 2.87Å; S546-L549 PolarHBondContact O-N 2.85Å; L549-K551 VanDerWaalsContact C-N 3.25Å; L549-K551 PolarHBondContact O-N 3.44Å; L549-A552 WeakPolarHBondContact O-CB 3.32Å; L549-A552 PolarHBondContact O-N 3.14Å; L549-A552 VanDerWaalsContact O-N 3.11Å
550	N	85	Confident	87.2	Confident	133 Å²	133	64.7 Å²	64.7	71%	0.711	32%	0.323	S	S	*	.	H	α-helix	trans	-68.8	-25.9	176.4	-68.4	-9.5	0	0	0	112.6	S546 K547	S546-N550 WeakPolarHBondContact O-CB 3.28Å; S546-N550 PolarHBondContact O-N 3.25Å; S546-N550 PolarHBondContact O-ND2 2.88Å; S546-N550 PolarHBondContact O-OD1 2.86Å; K547-N550 PolarHBondContact O-N 2.87Å
551	K	79.9	Confident	86	Confident	117 Å²	117	64.7 Å²	64.7	51%	0.509	34%	0.342	S	S	.	.	T	Hydrogen-bonded Turn	trans	-91	-3.6	172.6	-68.3	-178.6	-177.5	-174	0	113	N403 K547 A548 L549 H553	N403-K551 PolarHBondContact OD1-NZ 2.94Å; K547-K551 WeakPolarHBondContact O-CG 3.16Å; K547-K551 PolarHBondContact O-N 3.47Å; K547-K551 VanDerWaalsContact O-N 3.11Å; A548-K551 CarbonylContact O-C 3.55Å; A548-K551 PolarHBondContact O-N 3.39Å; L549-K551 VanDerWaalsContact C-N 3.25Å; L549-K551 PolarHBondContact O-N 3.44Å; K551-H553 PolarHBondContact O-N 3.26Å
552	A	76.3	Confident	84.1	Confident	25 Å²	25	59.8 Å²	59.8	21%	0.207	33%	0.332	C	S	.	.			trans	-69.5	133.9	-174.8	0	0	0	0	0	109.8	N123 V127 A548 L549	N123-A552 WeakPolarHBondContact ND2-CB 3.37Å; V127-A552 HydrophobicContact CG1-CB 4.3Å; A548-A552 PolarHBondContact O-N 2.9Å; L549-A552 WeakPolarHBondContact O-CB 3.32Å; L549-A552 PolarHBondContact O-N 3.14Å; L549-A552 VanDerWaalsContact O-N 3.11Å
553	H	79.2	Confident	82.2	Confident	59 Å²	59	58.6 Å²	58.6	27%	0.273	32%	0.32	S	S	.	.			trans	-81.1	178.2	171.9	-59.5	92	0	0	0	110.5	T121 R122 N123 K131 K551	T121-H553 CarbonylContact O-C 3.57Å; R122-H553 HydrophobicContact CB-CB 4.22Å; N123-H553 PolarHBondContact OD1-O 3.12Å; K131-H553 PolarHBondContact NZ-O 3.48Å; K551-H553 PolarHBondContact O-N 3.26Å
554	G	86.3	Confident	80.2	Confident	25 Å²	25	59.8 Å²	59.8	26%	0.258	32%	0.323	S	S	.	.	S	Bend	trans	72.5	177.5	172.5	0	0	0	0	0	114.2	T121 K131	T121-G554 WeakPolarHBondContact O-CA 3.42Å; K131-G554 PolarHBondContact NZ-O 3.05Å
555	C	89.1	Confident	78	Confident	0 Å²	0	59.1 Å²	59.1	0%	0	32%	0.32	C	S	.	.			trans	-73.4	151	-168	-55.3	0	0	0	0	112.7	F120 K131 F469	F120-C555 HydrophobicContact CD1-CB 3.79Å; F120-C555 HydrophobicContact CD2-CB 4.19Å; F120-C555 HydrophobicContact CE1-CB 3.35Å; F120-C555 HydrophobicContact CE2-CB 3.8Å; F120-C555 HydrophobicContact CG-CB 4.19Å; F120-C555 HydrophobicContact CZ-CB 3.36Å; F120-C555 PolarHBondContact O-N 3.34Å; K131-C555 PolarHBondContact NZ-O 2.91Å; K131-C555 VanDerWaalsContact NZ-O 3.16Å; F469-C555 WeakPolarHBondContact CE2-SG 3.3Å
556	D	89.9	Confident	76	Confident	64 Å²	64	61.3 Å²	61.3	34%	0.342	33%	0.333	S	S	.	.	B	Isolated β-bridge	trans	-82.9	123.4	159.6	-176.8	-24.5	0	0	0	108.9	Y558 N559 P560	D556-Y558 PolarHBondContact O-N 3.37Å; D556-Y558 PolarHBondContact OD1-N 3.37Å; D556-N559 HydrophobicContact CB-CB 4.2Å; D556-N559 CarbonylContact O-C 3.55Å; D556-N559 PolarHBondContact O-N 2.83Å; D556-N559 VanDerWaalsContact O-N 3.12Å; D556-N559 PolarHBondContact OD1-N 3.25Å; D556-P560 WeakPolarHBondContact O-CA 3.48Å
557	P	91	Very high	74	Confident	0 Å²	0	61.1 Å²	61.1	0%	0	33%	0.33	C	S	.	.	T	Hydrogen-bonded Turn	trans	-61.3	-24.4	178.6	26.8	-35.8	0	0	0	113.8	F120 K131 F132 Y456	F120-P557 HydrophobicContact CE1-CB 4.08Å; K131-P557 HydrophobicContact CB-CG 4.2Å; F132-P557 HydrophobicContact CD1-CB 4.16Å; F132-P557 HydrophobicContact CD1-CG 4.11Å; F132-P557 HydrophobicContact CD2-CG 3.98Å; F132-P557 HydrophobicContact CE1-CB 3.58Å; F132-P557 HydrophobicContact CE1-CG 3.97Å; F132-P557 HydrophobicContact CE2-CB 4.02Å; F132-P557 HydrophobicContact CE2-CG 3.82Å; F132-P557 HydrophobicContact CG-CG 4.14Å; F132-P557 HydrophobicContact CZ-CB 3.52Å; F132-P557 HydrophobicContact CZ-CG 3.83Å; Y456-P557 HydrophobicContact CD2-CB 4.4Å; Y456-P557 HydrophobicContact CE2-CB 3.8Å; Y456-P557 WeakPolarHBondContact CE2-O 3.43Å; Y456-P557 PolarHBondContact OH-O 2.92Å
558	Y	90.7	Very high	71.8	Confident	106 Å²	106	61.4 Å²	61.4	42%	0.416	33%	0.333	S	S	.	.	T	Hydrogen-bonded Turn	trans	-94	-13.9	176.8	-62.7	-74.7	0	0	0	113.3	F132 Y456 D556	F132-Y558 PolarHBondContact O-OH 2.93Å; Y456-Y558 HydrophobicContact CD2-CD1 4.44Å; Y456-Y558 AromaticContact CD2-CE1 3.73Å; Y456-Y558 HydrophobicContact CD2-CE1 3.73Å; Y456-Y558 AromaticContact CD2-CZ 3.77Å; Y456-Y558 HydrophobicContact CE2-CD1 4Å; Y456-Y558 AromaticContact CE2-CE1 3.74Å; Y456-Y558 HydrophobicContact CE2-CE1 3.74Å; D556-Y558 PolarHBondContact O-N 3.37Å; D556-Y558 PolarHBondContact OD1-N 3.37Å
559	N	86.5	Confident	69.6	Low	81 Å²	81	66.6 Å²	66.6	43%	0.433	36%	0.356	S	S	.	.	B	Isolated β-bridge	trans	-134.7	70.8	172.5	-168.1	1.6	0	0	0	111.3	D556 A561 T562	D556-N559 HydrophobicContact CB-CB 4.2Å; D556-N559 CarbonylContact O-C 3.55Å; D556-N559 PolarHBondContact O-N 2.83Å; D556-N559 VanDerWaalsContact O-N 3.12Å; D556-N559 PolarHBondContact OD1-N 3.25Å; N559-A561 PolarHBondContact O-N 3.12Å; N559-A561 VanDerWaalsContact O-N 3.15Å; N559-T562 HydrophobicContact CB-CG2 3.97Å; N559-T562 VanDerWaalsContact CG-CG2 3.48Å; N559-T562 VanDerWaalsContact ND2-CG2 3.33Å; N559-T562 WeakPolarHBondContact ND2-CG2 3.16Å; N559-T562 WeakPolarHBondContact O-CB 3.44Å; N559-T562 VanDerWaalsContact O-CG2 3.3Å; N559-T562 WeakPolarHBondContact O-CG2 3.5Å; N559-T562 PolarHBondContact O-N 3.39Å; N559-T562 PolarHBondContact O-OG1 2.91Å
560	P	75.1	Confident	67.3	Low	57 Å²	57	67.7 Å²	67.7	37%	0.37	36%	0.361	S	S	.	.	G	3₁₀ helix	trans	-66.2	-17.9	-173.9	26.5	-35.3	0	0	0	113.8	F120 V464 D556 T562	F120-P560 HydrophobicContact CZ-CB 4.17Å; V464-P560 HydrophobicContact CG1-CB 3.99Å; V464-P560 HydrophobicContact CG1-CG 4.02Å; D556-P560 WeakPolarHBondContact O-CA 3.48Å; P560-T562 PolarHBondContact O-N 3.35Å; P560-T562 VanDerWaalsContact O-N 3.16Å
561	A	66.3	Low	65	Low	92 Å²	92	67.9 Å²	67.9	76%	0.76	36%	0.358	S	S	*	.	G	3₁₀ helix	trans	-68.2	-6.4	175.9	0	0	0	0	0	113.5	N559 Y563	N559-A561 PolarHBondContact O-N 3.12Å; N559-A561 VanDerWaalsContact O-N 3.15Å; A561-Y563 PolarHBondContact O-N 2.75Å
562	T	54.7	Low	63	Low	74 Å²	74	69.8 Å²	69.8	45%	0.454	36%	0.363	S	S	.	.	G	3₁₀ helix	trans	-73.6	-3.1	179.9	51.2	0	0	0	0	114.8	N559 P560 E564	N559-T562 HydrophobicContact CB-CG2 3.97Å; N559-T562 VanDerWaalsContact CG-CG2 3.48Å; N559-T562 VanDerWaalsContact ND2-CG2 3.33Å; N559-T562 WeakPolarHBondContact ND2-CG2 3.16Å; N559-T562 WeakPolarHBondContact O-CB 3.44Å; N559-T562 VanDerWaalsContact O-CG2 3.3Å; N559-T562 WeakPolarHBondContact O-CG2 3.5Å; N559-T562 PolarHBondContact O-N 3.39Å; N559-T562 PolarHBondContact O-OG1 2.91Å; P560-T562 PolarHBondContact O-N 3.35Å; P560-T562 VanDerWaalsContact O-N 3.16Å; T562-E564 PolarHBondContact O-N 2.84Å
563	Y	51.9	Low	61.2	Low	45 Å²	45	72.7 Å²	72.7	18%	0.176	38%	0.375	C	S	.	.			trans	-87.3	103.8	178.1	-164.6	-98.4	0	0	0	111.8	A561 N565 D567	A561-Y563 PolarHBondContact O-N 2.75Å; Y563-N565 HydrophobicContact CE1-CB 4.24Å; Y563-D567 PolarHBondContact OH-OD2 2.93Å
564	E	48.6	Very low	59.5	Low	123 Å²	123	72.5 Å²	72.5	58%	0.575	38%	0.38	S	S	*	.			trans	-76.1	123.8	156.4	-76.1	-175.7	175	0	0	108.9	L47 T562 T566	L47-E564 HydrophobicContact CD1-CG 4.48Å; L47-E564 VanDerWaalsContact CD1-OE1 3.23Å; L47-E564 WeakPolarHBondContact CD1-OE1 3.26Å; L47-E564 VanDerWaalsContact CD1-OE2 3.28Å; L47-E564 WeakPolarHBondContact CD1-OE2 3.44Å; T562-E564 PolarHBondContact O-N 2.84Å; E564-T566 VanDerWaalsContact C-N 3.32Å; E564-T566 PolarHBondContact O-N 2.79Å
565	N	45.1	Very low	57.3	Low	41 Å²	41	74.3 Å²	74.3	22%	0.219	39%	0.386	C	S	.	.			trans	-68.8	87.4	176.2	-169.9	3.6	0	0	0	110.2	Y563 D567 E568	Y563-N565 HydrophobicContact CE1-CB 4.24Å; N565-D567 VanDerWaalsContact C-N 3.26Å; N565-D567 WeakPolarHBondContact OD1-CB 3.37Å; N565-D567 PolarHBondContact OD1-N 3.09Å; N565-E568 WeakPolarHBondContact ND2-CG 3.39Å; N565-E568 PolarHBondContact ND2-OE1 3.49Å; N565-E568 PolarHBondContact OD1-N 3.32Å
566	T	48.3	Very low	54.9	Low	45 Å²	45	77.1 Å²	77.1	28%	0.276	40%	0.4	S	S	.	.	H	α-helix	trans	-77.6	-12.9	171.1	38.3	0	0	0	0	112.4	E564 E568 Q569 M570	E564-T566 VanDerWaalsContact C-N 3.32Å; E564-T566 PolarHBondContact O-N 2.79Å; T566-E568 VanDerWaalsContact C-N 3.35Å; T566-Q569 PolarHBondContact O-N 2.6Å; T566-M570 PolarHBondContact O-N 3.1Å; T566-M570 VanDerWaalsContact O-N 3.07Å
567	D	47.3	Very low	52.4	Low	31 Å²	31	78.6 Å²	78.6	17%	0.166	41%	0.408	C	S	.	.	H	α-helix	trans	-67	-36.5	177.2	-58.7	-42.6	0	0	0	111.2	Y563 N565 M570 E571	Y563-D567 PolarHBondContact OH-OD2 2.93Å; N565-D567 VanDerWaalsContact C-N 3.26Å; N565-D567 WeakPolarHBondContact OD1-CB 3.37Å; N565-D567 PolarHBondContact OD1-N 3.09Å; D567-M570 PolarHBondContact O-N 3.23Å; D567-E571 PolarHBondContact O-N 3.22Å
568	E	42.9	Very low	49.9	Very low	129 Å²	129	86.2 Å²	86.2	60%	0.603	44%	0.441	S	S	*	.	H	α-helix	trans	-67.6	-34.3	171.8	-88.4	171.4	-151.6	0	0	112.5	N565 T566 M570 Y572	N565-E568 WeakPolarHBondContact ND2-CG 3.39Å; N565-E568 PolarHBondContact ND2-OE1 3.49Å; N565-E568 PolarHBondContact OD1-N 3.32Å; T566-E568 VanDerWaalsContact C-N 3.35Å; E568-M570 VanDerWaalsContact C-N 3.31Å; E568-M570 PolarHBondContact O-N 2.96Å; E568-Y572 WeakPolarHBondContact O-CB 3.33Å; E568-Y572 PolarHBondContact O-N 2.93Å
569	Q	40.3	Very low	47.2	Very low	114 Å²	114	87.4 Å²	87.4	53%	0.533	45%	0.451	S	S	.	.	H	α-helix	trans	-66.8	-33.5	173.2	-81.8	-178.8	-11.4	0	0	111.9	T566 N573	T566-Q569 PolarHBondContact O-N 2.6Å; Q569-N573 WeakPolarHBondContact O-CB 3.4Å; Q569-N573 PolarHBondContact O-N 3.23Å; Q569-N573 PolarHBondContact O-ND2 2.94Å; Q569-N573 VanDerWaalsContact O-ND2 3.15Å
570	M	38.1	Very low	44.7	Very low	60 Å²	60	86.5 Å²	86.5	30%	0.296	45%	0.451	S	S	.	.	H	α-helix	trans	-72.6	-43.4	175	-81.8	-172.5	-85.9	0	0	112.6	E52 T566 D567 E568 N573 S574	E52-M570 HydrophobicContact CG-CE 4.44Å; E52-M570 HydrophobicContact CG-SD 3.93Å; E52-M570 VanDerWaalsContact OE1-CG 3.23Å; E52-M570 WeakPolarHBondContact OE1-CG 3.44Å; T566-M570 PolarHBondContact O-N 3.1Å; T566-M570 VanDerWaalsContact O-N 3.07Å; D567-M570 PolarHBondContact O-N 3.23Å; E568-M570 VanDerWaalsContact C-N 3.31Å; E568-M570 PolarHBondContact O-N 2.96Å; M570-N573 PolarHBondContact O-N 3.45Å; M570-S574 WeakPolarHBondContact O-CB 3.48Å; M570-S574 PolarHBondContact O-N 3.21Å; M570-S574 PolarHBondContact O-OG 3.29Å
571	E	37.4	Very low	42.7	Very low	138 Å²	138	89.9 Å²	89.9	65%	0.645	46%	0.464	S	S	*	.	H	α-helix	trans	-66.5	-42.7	176.7	-160.7	163.9	-154.7	0	0	110.1	D567 S574 T575	D567-E571 PolarHBondContact O-N 3.22Å; E571-S574 PolarHBondContact O-N 3.38Å; E571-S574 PolarHBondContact O-OG 3.36Å; E571-T575 WeakPolarHBondContact O-CB 3.44Å; E571-T575 PolarHBondContact O-N 2.7Å; E571-T575 PolarHBondContact O-OG1 3.07Å
572	Y	37.2	Very low	41	Very low	157 Å²	157	91.6 Å²	91.6	62%	0.616	46%	0.461	S	S	*	.	H	α-helix	trans	-61	-45.5	172.2	-171.7	-110.1	0	0	0	112.5	E568 T575 I576	E568-Y572 WeakPolarHBondContact O-CB 3.33Å; E568-Y572 PolarHBondContact O-N 2.93Å; Y572-T575 PolarHBondContact O-N 3.4Å; Y572-I576 HydrophobicContact CD1-CD1 3.55Å; Y572-I576 HydrophobicContact CD2-CD1 4.48Å; Y572-I576 HydrophobicContact CE1-CD1 3.18Å; Y572-I576 HydrophobicContact CE1-CG1 4.34Å; Y572-I576 HydrophobicContact CE2-CD1 4.17Å; Y572-I576 HydrophobicContact CG-CD1 4.2Å; Y572-I576 WeakPolarHBondContact O-CB 3.46Å; Y572-I576 VanDerWaalsContact O-CG1 3.31Å; Y572-I576 WeakPolarHBondContact O-CG1 3.3Å; Y572-I576 PolarHBondContact O-N 3.25Å
573	N	39.4	Very low	40	Very low	86 Å²	86	94.6 Å²	94.6	46%	0.46	47%	0.473	S	S	.	.	H	α-helix	trans	-71.4	-29.8	177.4	-73.6	-21	0	0	0	113.3	Q569 M570 N577	Q569-N573 WeakPolarHBondContact O-CB 3.4Å; Q569-N573 PolarHBondContact O-N 3.23Å; Q569-N573 PolarHBondContact O-ND2 2.94Å; Q569-N573 VanDerWaalsContact O-ND2 3.15Å; M570-N573 PolarHBondContact O-N 3.45Å; N573-N577 VanDerWaalsContact O-CB 3.29Å; N573-N577 WeakPolarHBondContact O-CB 3.32Å; N573-N577 PolarHBondContact O-N 3.36Å; N573-N577 PolarHBondContact O-ND2 2.93Å
574	S	42.9	Very low	39.1	Very low	55 Å²	55	97.8 Å²	97.8	39%	0.385	49%	0.493	S	S	.	.	H	α-helix	trans	-74	-31.9	173.6	78.3	0	0	0	0	111.8	M570 E571 K578	M570-S574 WeakPolarHBondContact O-CB 3.48Å; M570-S574 PolarHBondContact O-N 3.21Å; M570-S574 PolarHBondContact O-OG 3.29Å; E571-S574 PolarHBondContact O-N 3.38Å; E571-S574 PolarHBondContact O-OG 3.36Å; S574-K578 WeakPolarHBondContact O-CG 3.38Å; S574-K578 PolarHBondContact O-N 3.39Å
575	T	41.2	Very low	38.4	Very low	62 Å²	62	97.7 Å²	97.7	38%	0.38	50%	0.497	S	S	.	.	H	α-helix	trans	-74	-42.2	173.8	-46.8	0	0	0	0	110	E571 Y572 N577 K578 E579	E571-T575 WeakPolarHBondContact O-CB 3.44Å; E571-T575 PolarHBondContact O-N 2.7Å; E571-T575 PolarHBondContact O-OG1 3.07Å; Y572-T575 PolarHBondContact O-N 3.4Å; T575-N577 PolarHBondContact O-N 2.94Å; T575-K578 CarbonylContact O-C 3.51Å; T575-K578 WeakPolarHBondContact O-CA 3.41Å; T575-K578 WeakPolarHBondContact O-CB 3.29Å; T575-K578 PolarHBondContact O-N 3.45Å; T575-K578 VanDerWaalsContact O-N 3.1Å; T575-E579 WeakPolarHBondContact O-CB 3.38Å; T575-E579 WeakPolarHBondContact O-CG 3.37Å; T575-E579 PolarHBondContact O-N 2.91Å
576	I	39.3	Very low	38	Very low	59 Å²	59	100.1 Å²	100.1	30%	0.303	52%	0.516	S	S	.	.	H	α-helix	trans	-63.8	-38.4	170.1	-70.8	172.4	0	0	0	111.2	Y572 K578 E579 S580	Y572-I576 HydrophobicContact CD1-CD1 3.55Å; Y572-I576 HydrophobicContact CD2-CD1 4.48Å; Y572-I576 HydrophobicContact CE1-CD1 3.18Å; Y572-I576 HydrophobicContact CE1-CG1 4.34Å; Y572-I576 HydrophobicContact CE2-CD1 4.17Å; Y572-I576 HydrophobicContact CG-CD1 4.2Å; Y572-I576 WeakPolarHBondContact O-CB 3.46Å; Y572-I576 VanDerWaalsContact O-CG1 3.31Å; Y572-I576 WeakPolarHBondContact O-CG1 3.3Å; Y572-I576 PolarHBondContact O-N 3.25Å; I576-K578 VanDerWaalsContact C-N 3.27Å; I576-K578 PolarHBondContact O-N 2.95Å; I576-E579 CarbonylContact O-C 3.59Å; I576-E579 PolarHBondContact O-N 3.33Å; I576-S580 WeakPolarHBondContact O-CA 3.32Å; I576-S580 WeakPolarHBondContact O-CB 3.33Å; I576-S580 PolarHBondContact O-N 2.83Å; I576-S580 PolarHBondContact O-OG 3.15Å
577	N	37.4	Very low	37.4	Very low	96 Å²	96	103.5 Å²	103.5	51%	0.513	54%	0.537	S	S	.	.	H	α-helix	trans	-68.6	-28	174.4	-84.8	-27.7	0	0	0	111.6	N573 T575 S580 I581	N573-N577 VanDerWaalsContact O-CB 3.29Å; N573-N577 WeakPolarHBondContact O-CB 3.32Å; N573-N577 PolarHBondContact O-N 3.36Å; N573-N577 PolarHBondContact O-ND2 2.93Å; T575-N577 PolarHBondContact O-N 2.94Å; N577-S580 WeakPolarHBondContact CA-OG 3.21Å; N577-I581 VanDerWaalsContact O-CB 3.23Å; N577-I581 WeakPolarHBondContact O-CB 3.23Å; N577-I581 WeakPolarHBondContact O-CD1 3.34Å; N577-I581 WeakPolarHBondContact O-CG1 3.38Å; N577-I581 PolarHBondContact O-N 3.16Å; N577-I581 VanDerWaalsContact O-N 3.16Å
578	K	37	Very low	36.6	Very low	159 Å²	159	107.9 Å²	107.9	69%	0.691	56%	0.56	S	S	*	*	H	α-helix	trans	-75.2	-36.4	170.4	-75.7	176.7	-179.5	176.5	0	112.6	S574 T575 I576 N582	S574-K578 WeakPolarHBondContact O-CG 3.38Å; S574-K578 PolarHBondContact O-N 3.39Å; T575-K578 CarbonylContact O-C 3.51Å; T575-K578 WeakPolarHBondContact O-CA 3.41Å; T575-K578 WeakPolarHBondContact O-CB 3.29Å; T575-K578 PolarHBondContact O-N 3.45Å; T575-K578 VanDerWaalsContact O-N 3.1Å; I576-K578 VanDerWaalsContact C-N 3.27Å; I576-K578 PolarHBondContact O-N 2.95Å; K578-N582 PolarHBondContact O-N 3.2Å
579	E	34.1	Very low	36	Very low	131 Å²	131	107.1 Å²	107.1	61%	0.612	57%	0.567	S	S	*	*	H	α-helix	trans	-80.1	-27.6	177.6	-73.7	-179.1	166.7	0	0	113.3	T575 I576 N582	T575-E579 WeakPolarHBondContact O-CB 3.38Å; T575-E579 WeakPolarHBondContact O-CG 3.37Å; T575-E579 PolarHBondContact O-N 2.91Å; I576-E579 CarbonylContact O-C 3.59Å; I576-E579 PolarHBondContact O-N 3.33Å; E579-N582 WeakPolarHBondContact O-CB 3.1Å; E579-N582 PolarHBondContact O-N 3.44Å
580	S	34.8	Very low	35.6	Very low	63 Å²	63	108.2 Å²	108.2	44%	0.441	58%	0.582	S	S	.	*	H	α-helix	trans	-87.7	-12.1	174.4	62.6	0	0	0	0	112.8	I576 N577 N582	I576-S580 WeakPolarHBondContact O-CA 3.32Å; I576-S580 WeakPolarHBondContact O-CB 3.33Å; I576-S580 PolarHBondContact O-N 2.83Å; I576-S580 PolarHBondContact O-OG 3.15Å; N577-S580 WeakPolarHBondContact CA-OG 3.21Å; S580-N582 VanDerWaalsContact C-N 3.32Å
581	I	33.1	Very low	35	Very low	127 Å²	127	113.8 Å²	113.8	65%	0.651	61%	0.607	S	S	*	*	S	Bend	trans	-83.8	-7.4	162.3	-67.8	168.7	0	0	0	111.5	N577 I583	N577-I581 VanDerWaalsContact O-CB 3.23Å; N577-I581 WeakPolarHBondContact O-CB 3.23Å; N577-I581 WeakPolarHBondContact O-CD1 3.34Å; N577-I581 WeakPolarHBondContact O-CG1 3.38Å; N577-I581 PolarHBondContact O-N 3.16Å; N577-I581 VanDerWaalsContact O-N 3.16Å; I581-I583 PolarHBondContact O-N 3.14Å
582	N	30.4	Very low	34.8	Very low	129 Å²	129	119.2 Å²	119.2	69%	0.69	64%	0.639	S	S	*	*			trans	-73.7	65.4	156	-90.3	-15.1	0	0	0	109.1	K578 E579 S580 D584	K578-N582 PolarHBondContact O-N 3.2Å; E579-N582 WeakPolarHBondContact O-CB 3.1Å; E579-N582 PolarHBondContact O-N 3.44Å; S580-N582 VanDerWaalsContact C-N 3.32Å; N582-D584 VanDerWaalsContact C-N 3.26Å; N582-D584 PolarHBondContact O-N 3.45Å
583	I	33.2	Very low	34.7	Very low	136 Å²	136	117.3 Å²	117.3	70%	0.697	64%	0.64	S	S	*	*			trans	-67.4	96	160.1	-61.8	174.7	0	0	0	105.2	I581 D585	I581-I583 PolarHBondContact O-N 3.14Å; I583-D585 PolarHBondContact O-N 3.12Å
584	D	32.5	Very low	34.4	Very low	112 Å²	112	118.9 Å²	118.9	60%	0.599	65%	0.65	S	S	*	*			trans	24.1	68.4	150.8	-138.5	-8.7	0	0	0	116	N582 S586 T587	N582-D584 VanDerWaalsContact C-N 3.26Å; N582-D584 PolarHBondContact O-N 3.45Å; D584-S586 PolarHBondContact O-N 3.49Å; D584-S586 WeakPolarHBondContact OD1-CB 3.17Å; D584-S586 PolarHBondContact OD1-OG 3.36Å; D584-T587 PolarHBondContact O-N 3.48Å
585	D	34.2	Very low	34	Very low	122 Å²	122	122.5 Å²	122.5	65%	0.652	66%	0.664	S	S	*	*	G	3₁₀ helix	trans	-66.1	8.2	168.6	-93.9	-19.8	0	0	0	112.3	I583 T587	I583-D585 PolarHBondContact O-N 3.12Å; D585-T587 PolarHBondContact O-N 3.38Å
586	S	36.6	Very low	33.5	Very low	91 Å²	91	126.1 Å²	126.1	64%	0.636	68%	0.681	S	S	*	*	G	3₁₀ helix	trans	-69.7	-1.2	168.4	74.6	0	0	0	0	113.6	D584	D584-S586 PolarHBondContact O-N 3.49Å; D584-S586 WeakPolarHBondContact OD1-CB 3.17Å; D584-S586 PolarHBondContact OD1-OG 3.36Å
587	T	36.4	Very low	33.2	Very low	116 Å²	116	130.3 Å²	130.3	71%	0.712	71%	0.705	S	S	*	*	G	3₁₀ helix	trans	-118.3	11.1	176.4	-15.3	0	0	0	0	115.7	D584 D585	D584-T587 PolarHBondContact O-N 3.48Å; D585-T587 PolarHBondContact O-N 3.38Å
588	I	29.7	Very low	32.9	Very low	124 Å²	124	132.5 Å²	132.5	64%	0.636	72%	0.717	S	S	*	*	S	Bend	trans	-116	114.6	173.3	-59.6	178.9	0	0	0	109.4
589	C	31	Very low	32.6	Very low	113 Å²	113	130.6 Å²	130.6	76%	0.764	72%	0.719	S	S	*	*			trans	86.8	51.5	173	-60.9	0	0	0	0	118.1
590	T	31.9	Very low	32.5	Very low	136 Å²	136	130.6 Å²	130.6	83%	0.834	73%	0.728	S	S	*	*	S	Bend		-101.2	89.7	128.1	20.3	0	0	0	0	108.1
591	Q	26.2	Very low	32.3	Very low	178 Å²	178	136.3 Å²	136.3	83%	0.832	75%	0.751	S	S	*	*			trans	157.7	123.4	151.8	-89.2	172.8	10.5	0	0	109.8
592	L	32.6	Very low	32.2	Very low	251 Å²	251	137.1 Å²	137.1	100%	1.314	76%	0.761	S	S	*	*			trans	80.8	0	173.4	-66.1	160.1	0	0	0	116.6

Retrieved 592 of 592 residues in 494.6 ms (Link to these results)

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