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Golgi pH regulator A

Voltage-gated channel that enables the transfer of monoatomic anions such as iodide, chloride, bromide and fluoride which may function in counter-ion conductance and participates in Golgi acidification¹. Plays a role in lymphocyte development, probably by acting as a RABL3 effector in hematopoietic cells (By similarity). Essential for maintaining the acidic luminal pH of the Golgi apparatus in neurons, which is important for preserving Golgi structural integrity (By similarity). This integrity supports proper axonal transport and synaptic maintenance in cerebellar inhibitory neurons, including Purkinje and basket cells (By similarity). Additionally, Golgi acidification facilitates the activation of SREBP2, thereby ensuring sufficient cholesterol biosynthesis necessary for normal neuronal morphology and function (By similarity).

AlphaFold DB , UniProt , Accession B7ZAQ6, Species HUMAN (Homo sapiens, Human), Gene GPHRA, Length 455 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	61.9	Low	89.4	Confident	189 Å²	189	74.9 Å²	74.9	93%	0.931	40%	0.4	S	S	*	.				0	-50.3	0	-71.4	-53.5	-160.1	0	0	112.3	F3 L4 I5	M1-F3 PolarHBondContact O-N 3Å; M1-L4 PolarHBondContact O-N 3.49Å; M1-I5 PolarHBondContact O-N 3.46Å
2	S	86	Confident	89.9	Confident	63 Å²	63	75.4 Å²	75.4	44%	0.441	41%	0.408	S	S	.	.	H	α-helix	trans	-59.8	-42.9	-175.5	63.4	0	0	0	0	114.5	L4 I5 D6 N67	S2-L4 VanDerWaalsContact C-N 3.3Å; S2-L4 PolarHBondContact O-N 3.28Å; S2-I5 PolarHBondContact O-N 3.14Å; S2-I5 VanDerWaalsContact O-N 3.17Å; S2-D6 WeakPolarHBondContact O-CB 3.38Å; S2-D6 PolarHBondContact O-N 3.45Å; S2-N67 WeakPolarHBondContact CB-ND2 3.44Å; S2-N67 PolarHBondContact OG-ND2 2.86Å; S2-N67 VanDerWaalsContact OG-ND2 3.08Å
3	F	90.7	Very high	90.3	Very high	85 Å²	85	70.4 Å²	70.4	37%	0.373	38%	0.382	S	S	.	.	H	α-helix	trans	-59.9	-36	178.2	-177.6	-100.5	0	0	0	113.8	M1 S7 F73	M1-F3 PolarHBondContact O-N 3Å; F3-S7 VanDerWaalsContact O-CB 3.25Å; F3-S7 WeakPolarHBondContact O-CB 3.31Å; F3-S7 PolarHBondContact O-N 3.3Å; F3-S7 PolarHBondContact O-OG 3.42Å; F3-F73 HydrophobicContact CE2-CB 4.23Å; F3-F73 AromaticContact CE2-CD1 3.7Å; F3-F73 HydrophobicContact CE2-CD1 3.7Å; F3-F73 HydrophobicContact CE2-CE1 4.31Å; F3-F73 HydrophobicContact CE2-CG 4.05Å; F3-F73 AromaticContact CZ-CD1 3.55Å; F3-F73 HydrophobicContact CZ-CD1 3.55Å; F3-F73 AromaticContact CZ-CE1 3.69Å; F3-F73 HydrophobicContact CZ-CE1 3.69Å; F3-F73 HydrophobicContact CZ-CG 4.13Å; F3-F73 HydrophobicContact CZ-CZ 4.36Å
4	L	91.3	Very high	90.6	Very high	121 Å²	121	67.9 Å²	67.9	63%	0.634	37%	0.366	S	S	*	.	H	α-helix	trans	-70.5	-39.5	177.7	-70.1	174.7	0	0	0	111.5	M1 S2 S7 S8	M1-L4 PolarHBondContact O-N 3.49Å; S2-L4 VanDerWaalsContact C-N 3.3Å; S2-L4 PolarHBondContact O-N 3.28Å; L4-S7 PolarHBondContact O-N 2.92Å; L4-S8 WeakPolarHBondContact O-CB 3.18Å; L4-S8 PolarHBondContact O-N 3.49Å
5	I	92.7	Very high	90.9	Very high	98 Å²	98	70.7 Å²	70.7	50%	0.503	38%	0.379	S	S	.	.	H	α-helix	trans	-64.8	-49.3	175.1	-62.9	168.5	0	0	0	109.2	M1 S2 S7 S8 I9	M1-I5 PolarHBondContact O-N 3.46Å; S2-I5 PolarHBondContact O-N 3.14Å; S2-I5 VanDerWaalsContact O-N 3.17Å; I5-S7 VanDerWaalsContact C-N 3.3Å; I5-S7 PolarHBondContact O-N 3.12Å; I5-S8 WeakPolarHBondContact O-CB 3.32Å; I5-S8 PolarHBondContact O-N 3.01Å; I5-S8 PolarHBondContact O-OG 3.07Å; I5-I9 HydrophobicContact CG2-CD1 4.15Å; I5-I9 WeakPolarHBondContact O-CG1 3.44Å; I5-I9 PolarHBondContact O-N 2.97Å
6	D	92.8	Very high	91.2	Very high	14 Å²	14	73.7 Å²	73.7	8%	0.075	40%	0.395	C	S	.	.	H	α-helix	trans	-56.7	-45.6	177.3	-67.6	-8.6	0	0	0	110.9	S2 S8 I9 M10 L66 N67 S70	S2-D6 WeakPolarHBondContact O-CB 3.38Å; S2-D6 PolarHBondContact O-N 3.45Å; D6-S8 VanDerWaalsContact C-N 3.34Å; D6-S8 PolarHBondContact O-N 3.14Å; D6-I9 PolarHBondContact O-N 2.89Å; D6-M10 WeakPolarHBondContact O-CG 3.33Å; D6-M10 PolarHBondContact O-N 3.35Å; D6-L66 HydrophobicContact CB-CB 4.45Å; D6-L66 HydrophobicContact CB-CD2 3.67Å; D6-L66 WeakPolarHBondContact OD1-CD2 3.41Å; D6-N67 PolarHBondContact OD2-N 3.41Å; D6-N67 VanDerWaalsContact OD2-N 3.13Å; D6-N67 PolarHBondContact OD2-ND2 3.11Å; D6-S70 WeakPolarHBondContact CB-OG 3.42Å; D6-S70 VanDerWaalsContact OD2-CB 3.23Å; D6-S70 WeakPolarHBondContact OD2-CB 3.48Å; D6-S70 PolarHBondContact OD2-OG 2.92Å
7	S	93.2	Very high	91.4	Very high	16 Å²	16	72.6 Å²	72.6	11%	0.112	39%	0.386	C	S	.	.	H	α-helix	trans	-63.4	-37.8	175.6	-67.2	0	0	0	0	112.6	F3 L4 I5 M10 I11 H74	F3-S7 VanDerWaalsContact O-CB 3.25Å; F3-S7 WeakPolarHBondContact O-CB 3.31Å; F3-S7 PolarHBondContact O-N 3.3Å; F3-S7 PolarHBondContact O-OG 3.42Å; L4-S7 PolarHBondContact O-N 2.92Å; I5-S7 VanDerWaalsContact C-N 3.3Å; I5-S7 PolarHBondContact O-N 3.12Å; S7-M10 PolarHBondContact O-N 2.97Å; S7-I11 WeakPolarHBondContact O-CB 3.34Å; S7-I11 WeakPolarHBondContact O-CD1 3.38Å; S7-I11 WeakPolarHBondContact O-CG1 3.43Å; S7-I11 PolarHBondContact O-N 3.33Å; S7-H74 PolarHBondContact OG-NE2 3.49Å
8	S	93.5	Very high	91.7	Very high	60 Å²	60	72 Å²	72	42%	0.42	38%	0.379	S	S	.	.	H	α-helix	trans	-66.6	-38	177.7	75.4	0	0	0	0	112.3	L4 I5 D6 I11 T12	L4-S8 WeakPolarHBondContact O-CB 3.18Å; L4-S8 PolarHBondContact O-N 3.49Å; I5-S8 WeakPolarHBondContact O-CB 3.32Å; I5-S8 PolarHBondContact O-N 3.01Å; I5-S8 PolarHBondContact O-OG 3.07Å; D6-S8 VanDerWaalsContact C-N 3.34Å; D6-S8 PolarHBondContact O-N 3.14Å; S8-I11 PolarHBondContact O-N 2.92Å; S8-T12 WeakPolarHBondContact O-CB 3.23Å; S8-T12 PolarHBondContact O-N 3.31Å; S8-T12 PolarHBondContact O-OG1 2.92Å
9	I	93.7	Very high	91.8	Very high	69 Å²	69	70.2 Å²	70.2	35%	0.354	38%	0.38	S	S	.	.	H	α-helix	trans	-62.3	-49.2	174.1	-65.8	166.4	0	0	0	108.9	I5 D6 I11 T12 S13 F60 L66	I5-I9 HydrophobicContact CG2-CD1 4.15Å; I5-I9 WeakPolarHBondContact O-CG1 3.44Å; I5-I9 PolarHBondContact O-N 2.97Å; D6-I9 PolarHBondContact O-N 2.89Å; I9-I11 PolarHBondContact O-N 3.09Å; I9-T12 WeakPolarHBondContact O-CB 3.28Å; I9-T12 PolarHBondContact O-N 3.49Å; I9-S13 PolarHBondContact O-N 2.95Å; I9-F60 HydrophobicContact CG2-CZ 4.44Å; I9-L66 HydrophobicContact CB-CD2 4.47Å; I9-L66 HydrophobicContact CD1-CD2 4.09Å
10	M	93.9	Very high	91.8	Very high	10 Å²	10	72.2 Å²	72.2	5%	0.049	39%	0.385	C	S	.	.	H	α-helix	trans	-63.9	-38.5	180	-69.3	-53.2	-34.1	0	0	113.7	D6 S7 T12 S13 Q14 T53 E56 L57 F60 L66	D6-M10 WeakPolarHBondContact O-CG 3.33Å; D6-M10 PolarHBondContact O-N 3.35Å; S7-M10 PolarHBondContact O-N 2.97Å; M10-T12 VanDerWaalsContact C-N 3.33Å; M10-S13 PolarHBondContact O-OG 3.48Å; M10-Q14 VanDerWaalsContact O-CB 3.25Å; M10-Q14 WeakPolarHBondContact O-CB 3.33Å; M10-Q14 PolarHBondContact O-N 3.23Å; M10-T53 HydrophobicContact CE-CG2 3.57Å; M10-E56 VanDerWaalsContact CE-OE2 3.27Å; M10-E56 WeakPolarHBondContact CE-OE2 3.5Å; M10-L57 HydrophobicContact CE-CD2 4.13Å; M10-L57 HydrophobicContact CE-CG 4.44Å; M10-L57 HydrophobicContact SD-CD2 3.94Å; M10-F60 HydrophobicContact CE-CE2 4.44Å; M10-F60 HydrophobicContact SD-CD2 3.86Å; M10-F60 HydrophobicContact SD-CE2 3.57Å; M10-F60 VanDerWaalsContact SD-CE2 3.57Å; M10-L66 HydrophobicContact CG-CD1 4.11Å; M10-L66 HydrophobicContact SD-CD1 3.69Å
11	I	94	Very high	91.7	Very high	99 Å²	99	68.7 Å²	68.7	51%	0.508	37%	0.367	S	S	.	.	H	α-helix	trans	-68	-39.1	176.9	-70.6	164.7	0	0	0	110.1	S7 S8 I9 Q14 I15	S7-I11 WeakPolarHBondContact O-CB 3.34Å; S7-I11 WeakPolarHBondContact O-CD1 3.38Å; S7-I11 WeakPolarHBondContact O-CG1 3.43Å; S7-I11 PolarHBondContact O-N 3.33Å; S8-I11 PolarHBondContact O-N 2.92Å; I9-I11 PolarHBondContact O-N 3.09Å; I11-Q14 PolarHBondContact O-N 3.49Å; I11-I15 HydrophobicContact CG2-CD1 3.82Å; I11-I15 HydrophobicContact CG2-CG1 4.43Å; I11-I15 VanDerWaalsContact O-CG1 3.26Å; I11-I15 WeakPolarHBondContact O-CG1 3.45Å; I11-I15 PolarHBondContact O-N 3.15Å
12	T	94.9	Very high	93.1	Very high	81 Å²	81	62.8 Å²	62.8	50%	0.497	33%	0.334	S	S	.	.	H	α-helix	trans	-63.1	-47.1	177.9	-57.5	0	0	0	0	110.9	S8 I9 M10 I15 L16	S8-T12 WeakPolarHBondContact O-CB 3.23Å; S8-T12 PolarHBondContact O-N 3.31Å; S8-T12 PolarHBondContact O-OG1 2.92Å; I9-T12 WeakPolarHBondContact O-CB 3.28Å; I9-T12 PolarHBondContact O-N 3.49Å; M10-T12 VanDerWaalsContact C-N 3.33Å; T12-I15 PolarHBondContact O-N 2.92Å; T12-L16 HydrophobicContact CG2-CD1 4.48Å; T12-L16 WeakPolarHBondContact O-CG 3.5Å; T12-L16 PolarHBondContact O-N 2.96Å
13	S	94.8	Very high	93.3	Very high	10 Å²	10	63.3 Å²	63.3	7%	0.07	33%	0.331	C	S	.	.	H	α-helix	trans	-63.9	-41	176.5	67.1	0	0	0	0	112	I9 M10 I15 L16 F17 E56	I9-S13 PolarHBondContact O-N 2.95Å; M10-S13 PolarHBondContact O-OG 3.48Å; S13-I15 VanDerWaalsContact C-N 3.35Å; S13-I15 PolarHBondContact O-N 3.32Å; S13-L16 WeakPolarHBondContact O-CB 3.46Å; S13-L16 PolarHBondContact O-N 2.62Å; S13-L16 VanDerWaalsContact O-N 3.16Å; S13-F17 VanDerWaalsContact O-CD2 3.29Å; S13-F17 WeakPolarHBondContact O-CD2 3.15Å; S13-F17 WeakPolarHBondContact O-CG 3.46Å; S13-F17 PolarHBondContact O-N 2.69Å; S13-E56 VanDerWaalsContact CB-CD 3.45Å; S13-E56 WeakPolarHBondContact CB-OE1 3.41Å; S13-E56 WeakPolarHBondContact CB-OE2 3.33Å; S13-E56 VanDerWaalsContact OG-CD 3.27Å; S13-E56 PolarHBondContact OG-OE1 2.85Å; S13-E56 PolarHBondContact OG-OE2 2.92Å
14	Q	94.5	Very high	93.1	Very high	35 Å²	35	60.8 Å²	60.8	16%	0.164	32%	0.32	C	S	.	.	H	α-helix	trans	-58.8	-43.3	175.3	-174.2	71.8	24.5	0	0	112.2	M10 I11 F17 F18 A49 F50 T53	M10-Q14 VanDerWaalsContact O-CB 3.25Å; M10-Q14 WeakPolarHBondContact O-CB 3.33Å; M10-Q14 PolarHBondContact O-N 3.23Å; I11-Q14 PolarHBondContact O-N 3.49Å; Q14-F17 PolarHBondContact O-N 3.2Å; Q14-F18 WeakPolarHBondContact O-CB 3.37Å; Q14-F18 PolarHBondContact O-N 3.18Å; Q14-A49 VanDerWaalsContact NE2-CB 3.27Å; Q14-F50 VanDerWaalsContact NE2-CD2 3.31Å; Q14-T53 PolarHBondContact OE1-OG1 2.85Å
15	I	95.9	Very high	92.8	Very high	110 Å²	110	55 Å²	55	56%	0.564	29%	0.29	S	S	*	.	H	α-helix	trans	-64.6	-41.7	176.8	-69.5	165.7	0	0	0	110.5	I11 T12 S13 F18 G19	I11-I15 HydrophobicContact CG2-CD1 3.82Å; I11-I15 HydrophobicContact CG2-CG1 4.43Å; I11-I15 VanDerWaalsContact O-CG1 3.26Å; I11-I15 WeakPolarHBondContact O-CG1 3.45Å; I11-I15 PolarHBondContact O-N 3.15Å; T12-I15 PolarHBondContact O-N 2.92Å; S13-I15 VanDerWaalsContact C-N 3.35Å; S13-I15 PolarHBondContact O-N 3.32Å; I15-F18 PolarHBondContact O-N 3.19Å; I15-G19 PolarHBondContact O-N 3.47Å
16	L	95.9	Very high	92.4	Very high	119 Å²	119	53.9 Å²	53.9	62%	0.623	28%	0.284	S	S	*	.	H	α-helix	trans	-63.4	-45.6	176.5	-70.3	173.8	0	0	0	111.8	T12 S13 F18 G19 F20	T12-L16 HydrophobicContact CG2-CD1 4.48Å; T12-L16 WeakPolarHBondContact O-CG 3.5Å; T12-L16 PolarHBondContact O-N 2.96Å; S13-L16 WeakPolarHBondContact O-CB 3.46Å; S13-L16 PolarHBondContact O-N 2.62Å; S13-L16 VanDerWaalsContact O-N 3.16Å; L16-F18 VanDerWaalsContact C-N 3.34Å; L16-F18 PolarHBondContact O-N 3.5Å; L16-G19 PolarHBondContact O-N 3.32Å; L16-F20 PolarHBondContact O-N 3.27Å
17	F	94.9	Very high	92	Very high	55 Å²	55	61.6 Å²	61.6	24%	0.241	31%	0.312	C	S	.	.	H	α-helix	trans	-65.6	-37.4	176.6	-64.1	-40.9	0	0	0	112.4	S13 Q14 F20 G21 A49 C52 E56	S13-F17 VanDerWaalsContact O-CD2 3.29Å; S13-F17 WeakPolarHBondContact O-CD2 3.15Å; S13-F17 WeakPolarHBondContact O-CG 3.46Å; S13-F17 PolarHBondContact O-N 2.69Å; Q14-F17 PolarHBondContact O-N 3.2Å; F17-F20 PolarHBondContact O-N 3.3Å; F17-G21 PolarHBondContact O-N 3.44Å; F17-A49 HydrophobicContact CB-CB 3.99Å; F17-C52 HydrophobicContact CB-CB 4.06Å; F17-C52 HydrophobicContact CD1-CB 3.77Å; F17-C52 HydrophobicContact CD2-CB 3.65Å; F17-C52 HydrophobicContact CE1-CB 4.07Å; F17-C52 HydrophobicContact CE2-CB 3.94Å; F17-C52 HydrophobicContact CG-CB 3.57Å; F17-C52 HydrophobicContact CZ-CB 4.15Å; F17-E56 HydrophobicContact CE2-CB 4.05Å; F17-E56 WeakPolarHBondContact CE2-OE2 3.47Å; F17-E56 HydrophobicContact CZ-CB 4.24Å
18	F	95.6	Very high	91.3	Very high	62 Å²	62	64.8 Å²	64.8	27%	0.272	33%	0.325	S	S	.	.	H	α-helix	trans	-62.2	-47.2	172.9	179.9	-91.2	0	0	0	111.2	Q14 I15 L16 F20 G21 W22 S45 V46 A49	Q14-F18 WeakPolarHBondContact O-CB 3.37Å; Q14-F18 PolarHBondContact O-N 3.18Å; I15-F18 PolarHBondContact O-N 3.19Å; L16-F18 VanDerWaalsContact C-N 3.34Å; L16-F18 PolarHBondContact O-N 3.5Å; F18-F20 VanDerWaalsContact C-N 3.32Å; F18-F20 PolarHBondContact O-N 2.73Å; F18-G21 PolarHBondContact O-N 3.27Å; F18-W22 HydrophobicContact CE1-CE3 4.15Å; F18-W22 AromaticContact CZ-CE3 3.82Å; F18-W22 HydrophobicContact CZ-CE3 3.82Å; F18-W22 HydrophobicContact CZ-CZ3 4.29Å; F18-W22 VanDerWaalsContact O-CB 3.3Å; F18-W22 WeakPolarHBondContact O-CB 3.48Å; F18-W22 PolarHBondContact O-N 2.85Å; F18-S45 VanDerWaalsContact CE2-CB 3.44Å; F18-V46 HydrophobicContact CD2-CG2 4.01Å; F18-V46 HydrophobicContact CE2-CG2 3.68Å; F18-A49 HydrophobicContact CB-CB 4Å
19	G	94.3	Very high	90.4	Very high	38 Å²	38	62.1 Å²	62.1	39%	0.392	31%	0.306	S	S	.	.	H	α-helix	trans	-59.7	-41.2	176	0	0	0	0	0	112.6	I15 L16 W22 L23	I15-G19 PolarHBondContact O-N 3.47Å; L16-G19 PolarHBondContact O-N 3.32Å; G19-W22 PolarHBondContact O-N 3.41Å; G19-L23 VanDerWaalsContact O-CB 3.32Å; G19-L23 WeakPolarHBondContact O-CB 3.46Å; G19-L23 PolarHBondContact O-N 3.49Å
20	F	92.1	Very high	89.3	Confident	109 Å²	109	61.9 Å²	61.9	48%	0.478	30%	0.302	S	S	.	.	H	α-helix	trans	-66.3	-45.6	175.2	-175.5	-90.6	0	0	0	112.2	L16 F17 F18 W22 L23 F24 F48	L16-F20 PolarHBondContact O-N 3.27Å; F17-F20 PolarHBondContact O-N 3.3Å; F18-F20 VanDerWaalsContact C-N 3.32Å; F18-F20 PolarHBondContact O-N 2.73Å; F20-W22 VanDerWaalsContact C-N 3.3Å; F20-W22 PolarHBondContact O-N 2.87Å; F20-L23 PolarHBondContact O-N 3.45Å; F20-F24 WeakPolarHBondContact O-CB 3.41Å; F20-F24 PolarHBondContact O-N 3.46Å; F20-F48 AromaticContact CD1-CE1 3.53Å; F20-F48 HydrophobicContact CD1-CE1 3.53Å; F20-F48 AromaticContact CD1-CZ 3.63Å; F20-F48 HydrophobicContact CD1-CZ 3.63Å; F20-F48 HydrophobicContact CE1-CE1 4.23Å; F20-F48 AromaticContact CE1-CZ 3.84Å; F20-F48 HydrophobicContact CE1-CZ 3.84Å
21	G	89.8	Confident	87.9	Confident	0 Å²	0	69 Å²	69	0%	0	33%	0.333	C	S	.	.	H	α-helix	trans	-59.7	-42	176	0	0	0	0	0	112	F17 F18 F24 F25 F48	F17-G21 PolarHBondContact O-N 3.44Å; F18-G21 PolarHBondContact O-N 3.27Å; G21-F24 PolarHBondContact O-N 3.01Å; G21-F25 WeakPolarHBondContact O-CB 3.36Å; G21-F25 PolarHBondContact O-N 3.2Å; G21-F48 VanDerWaalsContact CA-CD1 3.47Å
22	W	91.3	Very high	86.3	Confident	64 Å²	64	69.4 Å²	69.4	24%	0.242	34%	0.336	C	S	.	.	H	α-helix	trans	-63.8	-45.6	175	-171.5	-84.2	0	0	0	112.1	F18 G19 F20 F25 M26 Y38 Q41 V42 S45	F18-W22 HydrophobicContact CE1-CE3 4.15Å; F18-W22 AromaticContact CZ-CE3 3.82Å; F18-W22 HydrophobicContact CZ-CE3 3.82Å; F18-W22 HydrophobicContact CZ-CZ3 4.29Å; F18-W22 VanDerWaalsContact O-CB 3.3Å; F18-W22 WeakPolarHBondContact O-CB 3.48Å; F18-W22 PolarHBondContact O-N 2.85Å; G19-W22 PolarHBondContact O-N 3.41Å; F20-W22 VanDerWaalsContact C-N 3.3Å; F20-W22 PolarHBondContact O-N 2.87Å; W22-F25 WeakPolarHBondContact O-CB 3.41Å; W22-F25 PolarHBondContact O-N 3.26Å; W22-M26 WeakPolarHBondContact O-CG 3.28Å; W22-M26 PolarHBondContact O-N 2.88Å; W22-Y38 AromaticContact CH2-CD2 3.7Å; W22-Y38 HydrophobicContact CH2-CD2 3.7Å; W22-Y38 AromaticContact CH2-CE2 3.36Å; W22-Y38 HydrophobicContact CH2-CE2 3.36Å; W22-Y38 HydrophobicContact CZ2-CD2 4.39Å; W22-Y38 HydrophobicContact CZ2-CE2 4.02Å; W22-Y38 HydrophobicContact CZ3-CE2 4.21Å; W22-Q41 HydrophobicContact CE3-CB 4.3Å; W22-Q41 HydrophobicContact CH2-CB 3.59Å; W22-Q41 HydrophobicContact CH2-CG 4.47Å; W22-Q41 VanDerWaalsContact CH2-OE1 3.27Å; W22-Q41 HydrophobicContact CZ2-CB 4.35Å; W22-Q41 HydrophobicContact CZ3-CB 3.58Å; W22-V42 HydrophobicContact CH2-CG2 4.34Å; W22-V42 HydrophobicContact CZ3-CG2 3.78Å; W22-S45 VanDerWaalsContact CA-OG 3.31Å; W22-S45 WeakPolarHBondContact CA-OG 3.3Å; W22-S45 PolarHBondContact N-OG 3.39Å
23	L	90.4	Very high	84.8	Confident	74 Å²	74	68.1 Å²	68.1	39%	0.387	32%	0.323	S	S	.	.	H	α-helix	trans	-64.3	-44.3	177.9	-173.7	69.2	0	0	0	111.6	G19 F20 F25 M26 R27	G19-L23 VanDerWaalsContact O-CB 3.32Å; G19-L23 WeakPolarHBondContact O-CB 3.46Å; G19-L23 PolarHBondContact O-N 3.49Å; F20-L23 PolarHBondContact O-N 3.45Å; L23-F25 VanDerWaalsContact C-N 3.28Å; L23-F25 PolarHBondContact O-N 2.95Å; L23-M26 PolarHBondContact O-N 3.17Å; L23-R27 HydrophobicContact CD1-CG 4.13Å; L23-R27 HydrophobicContact CG-CG 4.38Å; L23-R27 WeakPolarHBondContact O-CB 3.49Å; L23-R27 WeakPolarHBondContact O-CG 3.45Å; L23-R27 PolarHBondContact O-N 3.18Å
24	F	86.6	Confident	83.2	Confident	33 Å²	33	74.2 Å²	74.2	15%	0.145	35%	0.35	C	S	.	.	H	α-helix	trans	-59.3	-43.8	176.1	178	-98.5	0	0	0	110.7	F20 G21 Q28 L29 F44 L360	F20-F24 WeakPolarHBondContact O-CB 3.41Å; F20-F24 PolarHBondContact O-N 3.46Å; G21-F24 PolarHBondContact O-N 3.01Å; F24-Q28 HydrophobicContact CD2-CB 4.11Å; F24-Q28 HydrophobicContact CE2-CB 3.86Å; F24-Q28 HydrophobicContact CE2-CG 3.95Å; F24-Q28 HydrophobicContact CZ-CB 4.13Å; F24-Q28 HydrophobicContact CZ-CG 4.14Å; F24-Q28 WeakPolarHBondContact O-CA 3.49Å; F24-Q28 VanDerWaalsContact O-CB 3.25Å; F24-Q28 WeakPolarHBondContact O-CB 3.3Å; F24-Q28 PolarHBondContact O-N 2.84Å; F24-L29 HydrophobicContact CD1-CD1 3.74Å; F24-L29 HydrophobicContact CE1-CD1 3.45Å; F24-L29 VanDerWaalsContact CE1-CD1 3.45Å; F24-L29 HydrophobicContact CZ-CD1 4.4Å; F24-F44 HydrophobicContact CD1-CE1 4.22Å; F24-F44 HydrophobicContact CD1-CZ 4.28Å; F24-F44 HydrophobicContact CE1-CZ 4.39Å; F24-L360 HydrophobicContact CD1-CD2 4.16Å; F24-L360 HydrophobicContact CD2-CD1 4.34Å; F24-L360 HydrophobicContact CE1-CB 4.5Å; F24-L360 HydrophobicContact CE1-CD2 3.63Å; F24-L360 HydrophobicContact CE1-CG 4.45Å; F24-L360 HydrophobicContact CE2-CB 4.19Å; F24-L360 HydrophobicContact CE2-CD1 4.12Å; F24-L360 HydrophobicContact CZ-CB 3.83Å; F24-L360 HydrophobicContact CZ-CD1 4.26Å; F24-L360 HydrophobicContact CZ-CD2 3.84Å; F24-L360 HydrophobicContact CZ-CG 4.18Å
25	F	84.1	Confident	81.6	Confident	0 Å²	0	72.8 Å²	72.8	0%	0	34%	0.343	C	S	.	.	I	π-helix	trans	-57.2	-52.7	174.8	-170.8	-93.2	0	0	0	112.3	G21 W22 L23 L29 F30 I35 Q41 F44 V380	G21-F25 WeakPolarHBondContact O-CB 3.36Å; G21-F25 PolarHBondContact O-N 3.2Å; W22-F25 WeakPolarHBondContact O-CB 3.41Å; W22-F25 PolarHBondContact O-N 3.26Å; L23-F25 VanDerWaalsContact C-N 3.28Å; L23-F25 PolarHBondContact O-N 2.95Å; F25-L29 HydrophobicContact CD2-CB 4.25Å; F25-L29 HydrophobicContact CD2-CD1 4.05Å; F25-L29 HydrophobicContact CE2-CB 4.36Å; F25-L29 WeakPolarHBondContact O-CB 3.41Å; F25-L29 PolarHBondContact O-N 3.34Å; F25-L29 VanDerWaalsContact O-N 3.12Å; F25-F30 HydrophobicContact CE1-CD2 4.47Å; F25-F30 PolarHBondContact O-N 3.37Å; F25-I35 HydrophobicContact CE1-CB 4.41Å; F25-I35 HydrophobicContact CE1-CD1 3.74Å; F25-I35 HydrophobicContact CE1-CG2 4.29Å; F25-I35 HydrophobicContact CE2-CD1 4.01Å; F25-I35 HydrophobicContact CZ-CB 4.36Å; F25-I35 HydrophobicContact CZ-CD1 3.23Å; F25-I35 HydrophobicContact CZ-CG1 4.36Å; F25-I35 HydrophobicContact CZ-CG2 3.98Å; F25-Q41 HydrophobicContact CD1-CB 4.13Å; F25-Q41 HydrophobicContact CD1-CG 4.05Å; F25-Q41 HydrophobicContact CE1-CB 3.95Å; F25-Q41 HydrophobicContact CE1-CG 3.46Å; F25-Q41 VanDerWaalsContact CE1-CG 3.46Å; F25-Q41 HydrophobicContact CZ-CB 4.49Å; F25-Q41 HydrophobicContact CZ-CG 4.08Å; F25-F44 HydrophobicContact CB-CD1 4.12Å; F25-F44 HydrophobicContact CB-CE1 4.3Å; F25-F44 HydrophobicContact CD2-CB 4.2Å; F25-F44 AromaticContact CD2-CD1 3.57Å; F25-F44 HydrophobicContact CD2-CD1 3.57Å; F25-F44 HydrophobicContact CD2-CD2 4.38Å; F25-F44 HydrophobicContact CD2-CE1 4.02Å; F25-F44 AromaticContact CD2-CG 3.78Å; F25-F44 HydrophobicContact CD2-CG 3.78Å; F25-F44 HydrophobicContact CE2-CB 4.34Å; F25-F44 HydrophobicContact CE2-CD1 4.42Å; F25-F44 HydrophobicContact CE2-CG 4.2Å; F25-F44 HydrophobicContact CG-CD1 4.24Å; F25-V380 HydrophobicContact CD2-CG1 4.46Å; F25-V380 HydrophobicContact CE2-CB 4.3Å; F25-V380 HydrophobicContact CE2-CG1 3.4Å; F25-V380 VanDerWaalsContact CE2-CG1 3.4Å; F25-V380 HydrophobicContact CE2-CG2 3.91Å; F25-V380 HydrophobicContact CZ-CG1 3.95Å; F25-V380 HydrophobicContact CZ-CG2 4.2Å
26	M	84.1	Confident	80.1	Confident	74 Å²	74	76.4 Å²	76.4	37%	0.365	35%	0.35	S	S	.	.	I	π-helix	trans	-69.4	-33.7	-176.8	-69.8	-63.3	-72.2	0	0	113.5	W22 L23 F30	W22-M26 WeakPolarHBondContact O-CG 3.28Å; W22-M26 PolarHBondContact O-N 2.88Å; L23-M26 PolarHBondContact O-N 3.17Å; M26-F30 WeakPolarHBondContact O-CB 2.93Å; M26-F30 HydrophobicContact SD-CD2 4.48Å; M26-F30 HydrophobicContact SD-CG 4.43Å
27	R	83.8	Confident	79.4	Confident	176 Å²	176	74.4 Å²	74.4	66%	0.664	34%	0.337	S	S	*	.	I	π-helix	trans	-88.5	-38.1	-177.6	-71.7	-171.3	175.5	177	2.4	113.4	L23	L23-R27 HydrophobicContact CD1-CG 4.13Å; L23-R27 HydrophobicContact CG-CG 4.38Å; L23-R27 WeakPolarHBondContact O-CB 3.49Å; L23-R27 WeakPolarHBondContact O-CG 3.45Å; L23-R27 PolarHBondContact O-N 3.18Å
28	Q	78.7	Confident	79.1	Confident	83 Å²	83	79.2 Å²	79.2	39%	0.388	36%	0.355	S	S	.	.	I	π-helix	trans	-103.5	-45.6	-170.5	-158.5	68.5	23.8	0	0	112.4	F24 T364 Y368	F24-Q28 HydrophobicContact CD2-CB 4.11Å; F24-Q28 HydrophobicContact CE2-CB 3.86Å; F24-Q28 HydrophobicContact CE2-CG 3.95Å; F24-Q28 HydrophobicContact CZ-CB 4.13Å; F24-Q28 HydrophobicContact CZ-CG 4.14Å; F24-Q28 WeakPolarHBondContact O-CA 3.49Å; F24-Q28 VanDerWaalsContact O-CB 3.25Å; F24-Q28 WeakPolarHBondContact O-CB 3.3Å; F24-Q28 PolarHBondContact O-N 2.84Å; Q28-T364 HydrophobicContact CG-CG2 3.8Å; Q28-Y368 PolarHBondContact O-OH 2.93Å
29	L	75.4	Confident	78.9	Confident	4 Å²	4	79 Å²	79	2%	0.021	36%	0.358	C	S	.	.	I	π-helix	trans	-84.1	-35.8	-179.2	-74.3	116.7	0	0	0	112.9	F24 F25 F44 F367 V380 L383	F24-L29 HydrophobicContact CD1-CD1 3.74Å; F24-L29 HydrophobicContact CE1-CD1 3.45Å; F24-L29 VanDerWaalsContact CE1-CD1 3.45Å; F24-L29 HydrophobicContact CZ-CD1 4.4Å; F25-L29 HydrophobicContact CD2-CB 4.25Å; F25-L29 HydrophobicContact CD2-CD1 4.05Å; F25-L29 HydrophobicContact CE2-CB 4.36Å; F25-L29 WeakPolarHBondContact O-CB 3.41Å; F25-L29 PolarHBondContact O-N 3.34Å; F25-L29 VanDerWaalsContact O-N 3.12Å; L29-F44 HydrophobicContact CD1-CE1 4.29Å; L29-F44 HydrophobicContact CD1-CE2 4.47Å; L29-F44 HydrophobicContact CD1-CZ 3.94Å; L29-F367 HydrophobicContact CD2-CB 4.22Å; L29-F367 HydrophobicContact CD2-CD1 4.27Å; L29-F367 HydrophobicContact CD2-CD2 3.88Å; L29-F367 HydrophobicContact CD2-CE2 4.3Å; L29-F367 HydrophobicContact CD2-CG 3.85Å; L29-F367 WeakPolarHBondContact O-CE1 3.23Å; L29-V380 HydrophobicContact CD2-CG2 4.36Å; L29-L383 HydrophobicContact CD2-CD1 3.88Å
30	F	69.6	Low	78.7	Confident	64 Å²	64	77.1 Å²	77.1	28%	0.281	34%	0.34	S	S	.	.	S	Bend	trans	-80.3	-15.3	-173.5	-164.4	-93.5	0	0	0	114.3	F25 M26 D32 Y33 I35	F25-F30 HydrophobicContact CE1-CD2 4.47Å; F25-F30 PolarHBondContact O-N 3.37Å; M26-F30 WeakPolarHBondContact O-CB 2.93Å; M26-F30 HydrophobicContact SD-CD2 4.48Å; M26-F30 HydrophobicContact SD-CG 4.43Å; F30-D32 PolarHBondContact O-N 3.36Å; F30-Y33 PolarHBondContact O-N 3.26Å; F30-Y33 VanDerWaalsContact O-N 3.11Å; F30-I35 HydrophobicContact CD2-CB 3.76Å; F30-I35 HydrophobicContact CD2-CD1 4.21Å; F30-I35 HydrophobicContact CD2-CG1 3.97Å; F30-I35 HydrophobicContact CE2-CB 3.73Å; F30-I35 HydrophobicContact CE2-CG1 4.31Å; F30-I35 VanDerWaalsContact CE2-N 3.27Å
31	K	65.1	Low	78.6	Confident	158 Å²	158	72.9 Å²	72.9	69%	0.687	32%	0.321	S	S	*	.	T	Hydrogen-bonded Turn	trans	-50.1	-32.8	-163.9	-165.4	177.3	177.2	-174.8	0	114.4
32	D	60.8	Low	78.8	Confident	108 Å²	108	74.8 Å²	74.8	58%	0.578	33%	0.333	S	S	*	.	T	Hydrogen-bonded Turn	trans	-124.3	2.6	-176	-53.3	-57.3	0	0	0	114.4	F30	F30-D32 PolarHBondContact O-N 3.36Å
33	Y	62.3	Low	78.9	Confident	55 Å²	55	72.4 Å²	72.4	22%	0.216	33%	0.325	C	S	.	.	S	Bend	trans	-135.2	123.7	-173.5	-65.7	-88.4	0	0	0	112.3	F30 I35 F367 Y368 S371	F30-Y33 PolarHBondContact O-N 3.26Å; F30-Y33 VanDerWaalsContact O-N 3.11Å; Y33-I35 VanDerWaalsContact C-N 3.32Å; Y33-I35 PolarHBondContact O-N 3.18Å; Y33-F367 AromaticContact CD2-CE1 3.71Å; Y33-F367 HydrophobicContact CD2-CE1 3.71Å; Y33-F367 HydrophobicContact CD2-CZ 4.19Å; Y33-F367 HydrophobicContact CE2-CE1 4.26Å; Y33-F367 HydrophobicContact CG-CE1 4.35Å; Y33-F367 HydrophobicContact CG-CZ 4.38Å; Y33-Y368 HydrophobicContact CE2-CD1 4.44Å; Y33-S371 VanDerWaalsContact CE1-O 3.25Å; Y33-S371 WeakPolarHBondContact CE1-O 3.47Å; Y33-S371 WeakPolarHBondContact CE2-OG 3.4Å; Y33-S371 VanDerWaalsContact CZ-CB 3.47Å; Y33-S371 VanDerWaalsContact CZ-O 3.31Å; Y33-S371 PolarHBondContact OH-O 3.2Å; Y33-S371 PolarHBondContact OH-OG 2.85Å
34	E	62.1	Low	79	Confident	138 Å²	138	69 Å²	69	65%	0.645	31%	0.307	S	S	*	.			trans	-67	85.4	173	-65.5	-177.5	175.1	0	0	111.1	R36	E34-R36 VanDerWaalsContact C-N 3.28Å; E34-R36 HydrophobicContact CB-CG 4.22Å; E34-R36 PolarHBondContact O-N 3.31Å
35	I	60.4	Low	79.3	Confident	4 Å²	4	67.4 Å²	67.4	2%	0.021	30%	0.3	C	S	.	.			trans	-76.6	88.8	168.4	-54.3	178.5	0	0	0	107.3	F25 F30 Y33 Q37 V40 Q41 F367 N377 V380	F25-I35 HydrophobicContact CE1-CB 4.41Å; F25-I35 HydrophobicContact CE1-CD1 3.74Å; F25-I35 HydrophobicContact CE1-CG2 4.29Å; F25-I35 HydrophobicContact CE2-CD1 4.01Å; F25-I35 HydrophobicContact CZ-CB 4.36Å; F25-I35 HydrophobicContact CZ-CD1 3.23Å; F25-I35 HydrophobicContact CZ-CG1 4.36Å; F25-I35 HydrophobicContact CZ-CG2 3.98Å; F30-I35 HydrophobicContact CD2-CB 3.76Å; F30-I35 HydrophobicContact CD2-CD1 4.21Å; F30-I35 HydrophobicContact CD2-CG1 3.97Å; F30-I35 HydrophobicContact CE2-CB 3.73Å; F30-I35 HydrophobicContact CE2-CG1 4.31Å; F30-I35 VanDerWaalsContact CE2-N 3.27Å; Y33-I35 VanDerWaalsContact C-N 3.32Å; Y33-I35 PolarHBondContact O-N 3.18Å; I35-Q37 PolarHBondContact O-N 3.49Å; I35-Q37 VanDerWaalsContact O-N 3.13Å; I35-V40 HydrophobicContact CG2-CB 4.43Å; I35-V40 HydrophobicContact CG2-CG1 4.32Å; I35-Q41 PolarHBondContact O-NE2 3.36Å; I35-F367 HydrophobicContact CD1-CZ 4.45Å; I35-N377 VanDerWaalsContact CG2-OD1 3.31Å; I35-N377 WeakPolarHBondContact CG2-OD1 3.42Å; I35-V380 HydrophobicContact CD1-CG2 3.66Å
36	R	64.7	Low	79.9	Confident	186 Å²	186	69.1 Å²	69.1	70%	0.702	31%	0.31	S	S	*	.			trans	-67.8	-9.8	-171.4	-74.7	175.6	-79.2	-159	-5.4	115	E34	E34-R36 VanDerWaalsContact C-N 3.28Å; E34-R36 HydrophobicContact CB-CG 4.22Å; E34-R36 PolarHBondContact O-N 3.31Å
37	Q	82.3	Confident	80.4	Confident	77 Å²	77	65.6 Å²	65.6	36%	0.36	29%	0.293	S	S	.	.			trans	-117.4	115	-169.8	-63.3	-138.5	-0.9	0	0	113.8	I35 V39 V40 F97	I35-Q37 PolarHBondContact O-N 3.49Å; I35-Q37 VanDerWaalsContact O-N 3.13Å; Q37-V39 PolarHBondContact O-N 3.13Å; Q37-V40 HydrophobicContact CB-CG2 4.18Å; Q37-V40 PolarHBondContact O-N 2.89Å; Q37-V40 VanDerWaalsContact O-N 3.17Å; Q37-F97 HydrophobicContact CB-CE1 4.47Å; Q37-F97 HydrophobicContact CB-CZ 4.23Å; Q37-F97 HydrophobicContact CG-CE1 4.08Å; Q37-F97 HydrophobicContact CG-CZ 4.31Å
38	Y	87.6	Confident	80.9	Confident	157 Å²	157	57.3 Å²	57.3	62%	0.616	26%	0.261	S	S	*	.	H	α-helix	trans	-52.9	-39.4	176.2	-177.3	-101	0	0	0	113	W22 V40 Q41 V42	W22-Y38 AromaticContact CH2-CD2 3.7Å; W22-Y38 HydrophobicContact CH2-CD2 3.7Å; W22-Y38 AromaticContact CH2-CE2 3.36Å; W22-Y38 HydrophobicContact CH2-CE2 3.36Å; W22-Y38 HydrophobicContact CZ2-CD2 4.39Å; W22-Y38 HydrophobicContact CZ2-CE2 4.02Å; W22-Y38 HydrophobicContact CZ3-CE2 4.21Å; Y38-V40 VanDerWaalsContact C-N 3.27Å; Y38-V40 PolarHBondContact O-N 2.91Å; Y38-Q41 WeakPolarHBondContact O-CB 3.22Å; Y38-Q41 PolarHBondContact O-N 3.43Å; Y38-Q41 VanDerWaalsContact O-N 3.09Å; Y38-V42 HydrophobicContact CD1-CG2 3.76Å; Y38-V42 HydrophobicContact CE1-CG2 3.32Å; Y38-V42 HydrophobicContact CE2-CG2 4.25Å; Y38-V42 HydrophobicContact CG-CG2 4.38Å; Y38-V42 WeakPolarHBondContact O-CG2 3.48Å; Y38-V42 PolarHBondContact O-N 2.9Å
39	V	91.4	Very high	81.7	Confident	56 Å²	56	53.3 Å²	53.3	34%	0.339	24%	0.243	S	C	.	.	H	α-helix	trans	-57.1	-40.5	-179.3	179	0	0	0	0	112	Q37 Q41 V42 I43 Y93	Q37-V39 PolarHBondContact O-N 3.13Å; V39-Q41 VanDerWaalsContact C-N 3.34Å; V39-Q41 PolarHBondContact O-N 3.17Å; V39-V42 PolarHBondContact O-N 3.28Å; V39-I43 HydrophobicContact CG1-CD1 3.67Å; V39-I43 HydrophobicContact CG1-CG1 4.35Å; V39-I43 WeakPolarHBondContact O-CB 3.32Å; V39-I43 VanDerWaalsContact O-CG1 3.25Å; V39-I43 WeakPolarHBondContact O-CG1 3.44Å; V39-I43 PolarHBondContact O-N 3.02Å; V39-Y93 HydrophobicContact CG1-CD1 4.11Å; V39-Y93 HydrophobicContact CG1-CE1 3.61Å; V39-Y93 HydrophobicContact CG1-CE2 4.39Å
40	V	90.6	Very high	82.6	Confident	0 Å²	0	54.8 Å²	54.8	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-65.9	-40.4	179.8	176.2	0	0	0	0	110.9	I35 Q37 Y38 I43 F44 F97 N377 V380 L381	I35-V40 HydrophobicContact CG2-CB 4.43Å; I35-V40 HydrophobicContact CG2-CG1 4.32Å; Q37-V40 HydrophobicContact CB-CG2 4.18Å; Q37-V40 PolarHBondContact O-N 2.89Å; Q37-V40 VanDerWaalsContact O-N 3.17Å; Y38-V40 VanDerWaalsContact C-N 3.27Å; Y38-V40 PolarHBondContact O-N 2.91Å; V40-I43 PolarHBondContact O-N 3.41Å; V40-F44 WeakPolarHBondContact O-CB 3.38Å; V40-F44 PolarHBondContact O-N 3.2Å; V40-F97 HydrophobicContact CG2-CD2 4.26Å; V40-F97 HydrophobicContact CG2-CE2 3.47Å; V40-F97 VanDerWaalsContact CG2-CE2 3.47Å; V40-F97 HydrophobicContact CG2-CZ 3.63Å; V40-N377 HydrophobicContact CG2-CB 4.15Å; V40-V380 HydrophobicContact CG1-CB 3.83Å; V40-V380 HydrophobicContact CG1-CG1 3.37Å; V40-L381 HydrophobicContact CG1-CD2 4.25Å; V40-L381 HydrophobicContact CG1-CG 4.12Å; V40-L381 HydrophobicContact CG2-CD1 4.3Å; V40-L381 HydrophobicContact CG2-CG 4.37Å
41	Q	90.2	Very high	83.7	Confident	20 Å²	20	51.7 Å²	51.7	9%	0.093	24%	0.236	C	C	.	.	H	α-helix	trans	-65.9	-42.6	179.2	-44.3	-169.9	-18.3	0	0	111	W22 F25 I35 Y38 V39 S45	W22-Q41 HydrophobicContact CE3-CB 4.3Å; W22-Q41 HydrophobicContact CH2-CB 3.59Å; W22-Q41 HydrophobicContact CH2-CG 4.47Å; W22-Q41 VanDerWaalsContact CH2-OE1 3.27Å; W22-Q41 HydrophobicContact CZ2-CB 4.35Å; W22-Q41 HydrophobicContact CZ3-CB 3.58Å; F25-Q41 HydrophobicContact CD1-CB 4.13Å; F25-Q41 HydrophobicContact CD1-CG 4.05Å; F25-Q41 HydrophobicContact CE1-CB 3.95Å; F25-Q41 HydrophobicContact CE1-CG 3.46Å; F25-Q41 VanDerWaalsContact CE1-CG 3.46Å; F25-Q41 HydrophobicContact CZ-CB 4.49Å; F25-Q41 HydrophobicContact CZ-CG 4.08Å; I35-Q41 PolarHBondContact O-NE2 3.36Å; Y38-Q41 WeakPolarHBondContact O-CB 3.22Å; Y38-Q41 PolarHBondContact O-N 3.43Å; Y38-Q41 VanDerWaalsContact O-N 3.09Å; V39-Q41 VanDerWaalsContact C-N 3.34Å; V39-Q41 PolarHBondContact O-N 3.17Å; Q41-S45 WeakPolarHBondContact O-CB 3.42Å; Q41-S45 PolarHBondContact O-N 2.89Å; Q41-S45 PolarHBondContact O-OG 2.63Å
42	V	93.3	Very high	85.1	Confident	39 Å²	39	44.6 Å²	44.6	24%	0.236	21%	0.205	C	C	.	.	H	α-helix	trans	-63.7	-50.9	176.1	175.4	0	0	0	0	110.2	W22 Y38 V39 F44 S45 V46	W22-V42 HydrophobicContact CH2-CG2 4.34Å; W22-V42 HydrophobicContact CZ3-CG2 3.78Å; Y38-V42 HydrophobicContact CD1-CG2 3.76Å; Y38-V42 HydrophobicContact CE1-CG2 3.32Å; Y38-V42 HydrophobicContact CE2-CG2 4.25Å; Y38-V42 HydrophobicContact CG-CG2 4.38Å; Y38-V42 WeakPolarHBondContact O-CG2 3.48Å; Y38-V42 PolarHBondContact O-N 2.9Å; V39-V42 PolarHBondContact O-N 3.28Å; V42-F44 VanDerWaalsContact C-N 3.32Å; V42-F44 PolarHBondContact O-N 3.38Å; V42-S45 PolarHBondContact O-N 3.01Å; V42-S45 VanDerWaalsContact O-N 3.17Å; V42-V46 HydrophobicContact CG1-CG2 3.89Å; V42-V46 WeakPolarHBondContact O-CB 3.5Å; V42-V46 VanDerWaalsContact O-CG2 3.25Å; V42-V46 WeakPolarHBondContact O-CG2 3.44Å; V42-V46 PolarHBondContact O-N 2.61Å
43	I	93.8	Very high	86.6	Confident	15 Å²	15	39.7 Å²	39.7	8%	0.077	18%	0.179	C	C	.	.	H	α-helix	trans	-57.9	-45.8	-179	-70.5	167.4	0	0	0	111.1	V39 V40 T47 V90 Y93 L381	V39-I43 HydrophobicContact CG1-CD1 3.67Å; V39-I43 HydrophobicContact CG1-CG1 4.35Å; V39-I43 WeakPolarHBondContact O-CB 3.32Å; V39-I43 VanDerWaalsContact O-CG1 3.25Å; V39-I43 WeakPolarHBondContact O-CG1 3.44Å; V39-I43 PolarHBondContact O-N 3.02Å; V40-I43 PolarHBondContact O-N 3.41Å; I43-T47 WeakPolarHBondContact O-CB 3.39Å; I43-T47 PolarHBondContact O-N 3.4Å; I43-T47 PolarHBondContact O-OG1 2.9Å; I43-V90 HydrophobicContact CG2-CG2 3.58Å; I43-Y93 HydrophobicContact CD1-CD1 4.31Å; I43-Y93 HydrophobicContact CD1-CD2 3.23Å; I43-Y93 HydrophobicContact CD1-CE2 3.56Å; I43-Y93 HydrophobicContact CD1-CG 3.65Å; I43-L381 HydrophobicContact CB-CD2 4.18Å; I43-L381 HydrophobicContact CD1-CD2 4.16Å; I43-L381 HydrophobicContact CG2-CD2 3.81Å
44	F	92.5	Very high	88	Confident	2 Å²	2	37.1 Å²	37.1	1%	0.009	17%	0.169	C	C	.	.	H	α-helix	trans	-59	-50	176.2	-178.8	-87.3	0	0	0	111.7	F24 F25 L29 V40 V42 T47 F48 V380 A384 M387	F24-F44 HydrophobicContact CD1-CE1 4.22Å; F24-F44 HydrophobicContact CD1-CZ 4.28Å; F24-F44 HydrophobicContact CE1-CZ 4.39Å; F25-F44 HydrophobicContact CB-CD1 4.12Å; F25-F44 HydrophobicContact CB-CE1 4.3Å; F25-F44 HydrophobicContact CD2-CB 4.2Å; F25-F44 AromaticContact CD2-CD1 3.57Å; F25-F44 HydrophobicContact CD2-CD1 3.57Å; F25-F44 HydrophobicContact CD2-CD2 4.38Å; F25-F44 HydrophobicContact CD2-CE1 4.02Å; F25-F44 AromaticContact CD2-CG 3.78Å; F25-F44 HydrophobicContact CD2-CG 3.78Å; F25-F44 HydrophobicContact CE2-CB 4.34Å; F25-F44 HydrophobicContact CE2-CD1 4.42Å; F25-F44 HydrophobicContact CE2-CG 4.2Å; F25-F44 HydrophobicContact CG-CD1 4.24Å; L29-F44 HydrophobicContact CD1-CE1 4.29Å; L29-F44 HydrophobicContact CD1-CE2 4.47Å; L29-F44 HydrophobicContact CD1-CZ 3.94Å; V40-F44 WeakPolarHBondContact O-CB 3.38Å; V40-F44 PolarHBondContact O-N 3.2Å; V42-F44 VanDerWaalsContact C-N 3.32Å; V42-F44 PolarHBondContact O-N 3.38Å; F44-T47 PolarHBondContact O-N 3.07Å; F44-F48 WeakPolarHBondContact O-CB 3.4Å; F44-F48 PolarHBondContact O-N 2.99Å; F44-V380 HydrophobicContact CB-CG1 4.29Å; F44-V380 HydrophobicContact CD2-CG1 4.14Å; F44-V380 HydrophobicContact CG-CG1 4.48Å; F44-A384 HydrophobicContact CD2-CB 3.96Å; F44-M387 HydrophobicContact CE2-CE 4.25Å; F44-M387 HydrophobicContact CE2-SD 4.18Å; F44-M387 HydrophobicContact CZ-CE 4.44Å; F44-M387 HydrophobicContact CZ-SD 4.1Å
45	S	93.7	Very high	89.4	Confident	0 Å²	0	30.7 Å²	30.7	0%	0	14%	0.139	C	C	.	.	H	α-helix	trans	-68	-38.1	-176.3	-54.3	0	0	0	0	112.5	F18 W22 Q41 V42 A49	F18-S45 VanDerWaalsContact CE2-CB 3.44Å; W22-S45 VanDerWaalsContact CA-OG 3.31Å; W22-S45 WeakPolarHBondContact CA-OG 3.3Å; W22-S45 PolarHBondContact N-OG 3.39Å; Q41-S45 WeakPolarHBondContact O-CB 3.42Å; Q41-S45 PolarHBondContact O-N 2.89Å; Q41-S45 PolarHBondContact O-OG 2.63Å; V42-S45 PolarHBondContact O-N 3.01Å; V42-S45 VanDerWaalsContact O-N 3.17Å; S45-A49 VanDerWaalsContact O-CB 3.3Å; S45-A49 WeakPolarHBondContact O-CB 3.43Å; S45-A49 PolarHBondContact O-N 3.29Å
46	V	95.6	Very high	90.8	Very high	35 Å²	35	31.8 Å²	31.8	21%	0.212	14%	0.144	C	C	.	.	H	α-helix	trans	-64.1	-47.5	172.9	175	0	0	0	0	110	F18 V42 F48 A49 F50 I85	F18-V46 HydrophobicContact CD2-CG2 4.01Å; F18-V46 HydrophobicContact CE2-CG2 3.68Å; V42-V46 HydrophobicContact CG1-CG2 3.89Å; V42-V46 WeakPolarHBondContact O-CB 3.5Å; V42-V46 VanDerWaalsContact O-CG2 3.25Å; V42-V46 WeakPolarHBondContact O-CG2 3.44Å; V42-V46 PolarHBondContact O-N 2.61Å; V46-F48 VanDerWaalsContact C-N 3.3Å; V46-F48 PolarHBondContact O-N 2.93Å; V46-A49 PolarHBondContact O-N 2.98Å; V46-F50 HydrophobicContact CG1-CD2 3.53Å; V46-F50 HydrophobicContact CG1-CE2 3.64Å; V46-F50 WeakPolarHBondContact O-CD2 3.25Å; V46-F50 PolarHBondContact O-N 3.31Å; V46-I85 HydrophobicContact CG1-CD1 3.54Å
47	T	94.9	Very high	92.1	Very high	0 Å²	0	23 Å²	23	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-60.1	-43.9	179.4	-54.6	0	0	0	0	110.7	I43 F44 S51 I82 I85 L86 M387	I43-T47 WeakPolarHBondContact O-CB 3.39Å; I43-T47 PolarHBondContact O-N 3.4Å; I43-T47 PolarHBondContact O-OG1 2.9Å; F44-T47 PolarHBondContact O-N 3.07Å; T47-S51 WeakPolarHBondContact O-CB 3.37Å; T47-S51 PolarHBondContact O-N 3.43Å; T47-S51 VanDerWaalsContact O-N 3.09Å; T47-S51 PolarHBondContact O-OG 2.98Å; T47-I82 HydrophobicContact CG2-CD1 4.02Å; T47-I85 WeakPolarHBondContact OG1-CG2 3.22Å; T47-L86 HydrophobicContact CG2-CD2 4.19Å; T47-M387 HydrophobicContact CG2-CE 3.88Å
48	F	93.7	Very high	92.5	Very high	2 Å²	2	19.3 Å²	19.3	1%	0.009	9%	0.094	C	C	.	.	H	α-helix	trans	-60.5	-47.8	175.1	-178.4	-92.9	0	0	0	111.5	F20 G21 F44 V46 S51 C52 I356 L360 M387	F20-F48 AromaticContact CD1-CE1 3.53Å; F20-F48 HydrophobicContact CD1-CE1 3.53Å; F20-F48 AromaticContact CD1-CZ 3.63Å; F20-F48 HydrophobicContact CD1-CZ 3.63Å; F20-F48 HydrophobicContact CE1-CE1 4.23Å; F20-F48 AromaticContact CE1-CZ 3.84Å; F20-F48 HydrophobicContact CE1-CZ 3.84Å; G21-F48 VanDerWaalsContact CA-CD1 3.47Å; F44-F48 WeakPolarHBondContact O-CB 3.4Å; F44-F48 PolarHBondContact O-N 2.99Å; V46-F48 VanDerWaalsContact C-N 3.3Å; V46-F48 PolarHBondContact O-N 2.93Å; F48-S51 WeakPolarHBondContact O-CB 3.48Å; F48-S51 PolarHBondContact O-N 2.8Å; F48-C52 WeakPolarHBondContact CE1-SG 3.38Å; F48-C52 WeakPolarHBondContact CZ-SG 3.46Å; F48-C52 PolarHBondContact O-N 3.42Å; F48-I356 HydrophobicContact CE2-CG2 4.48Å; F48-L360 HydrophobicContact CD2-CD2 4.42Å; F48-L360 HydrophobicContact CE2-CD1 4.18Å; F48-L360 HydrophobicContact CE2-CD2 4.03Å; F48-M387 HydrophobicContact CB-CE 3.73Å; F48-M387 HydrophobicContact CB-SD 4.27Å; F48-M387 HydrophobicContact CD2-CE 4.36Å; F48-M387 HydrophobicContact CD2-SD 3.78Å
49	A	95.4	Very high	92.5	Very high	0 Å²	0	14 Å²	14	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-60.6	-53.2	-178.7	0	0	0	0	0	112.4	Q14 F17 F18 S45 V46 S51 C52 T53	Q14-A49 VanDerWaalsContact NE2-CB 3.27Å; F17-A49 HydrophobicContact CB-CB 3.99Å; F18-A49 HydrophobicContact CB-CB 4Å; S45-A49 VanDerWaalsContact O-CB 3.3Å; S45-A49 WeakPolarHBondContact O-CB 3.43Å; S45-A49 PolarHBondContact O-N 3.29Å; V46-A49 PolarHBondContact O-N 2.98Å; A49-S51 PolarHBondContact O-N 2.96Å; A49-C52 PolarHBondContact O-N 3.19Å; A49-C52 VanDerWaalsContact O-N 3.15Å; A49-T53 PolarHBondContact O-N 3.04Å; A49-T53 PolarHBondContact O-OG1 2.9Å
50	F	95.3	Very high	92.5	Very high	34 Å²	34	12.5 Å²	12.5	15%	0.149	7%	0.065	C	C	.	.	H	α-helix	trans	-61.2	-27.8	177	-83.2	-82.5	0	0	0	112.9	Q14 V46 M54 N78 V81 I82 I85	Q14-F50 VanDerWaalsContact NE2-CD2 3.31Å; V46-F50 HydrophobicContact CG1-CD2 3.53Å; V46-F50 HydrophobicContact CG1-CE2 3.64Å; V46-F50 WeakPolarHBondContact O-CD2 3.25Å; V46-F50 PolarHBondContact O-N 3.31Å; F50-M54 WeakPolarHBondContact O-CG 3.42Å; F50-M54 PolarHBondContact O-N 2.94Å; F50-N78 WeakPolarHBondContact CD1-OD1 3.48Å; F50-N78 PolarHBondContact O-ND2 3.2Å; F50-N78 PolarHBondContact O-OD1 2.94Å; F50-V81 HydrophobicContact CD1-CB 4.01Å; F50-V81 HydrophobicContact CD1-CG1 3.9Å; F50-V81 HydrophobicContact CD2-CG1 4Å; F50-V81 HydrophobicContact CE1-CB 3.69Å; F50-V81 HydrophobicContact CE1-CG1 3.56Å; F50-V81 HydrophobicContact CE1-CG2 4.13Å; F50-V81 HydrophobicContact CE2-CG1 3.63Å; F50-V81 HydrophobicContact CG-CG1 4.16Å; F50-V81 HydrophobicContact CZ-CB 4.05Å; F50-V81 HydrophobicContact CZ-CG1 3.43Å; F50-V81 VanDerWaalsContact CZ-CG1 3.43Å; F50-V81 HydrophobicContact CZ-CG2 4.36Å; F50-I82 HydrophobicContact CB-CB 4.36Å; F50-I82 HydrophobicContact CB-CD1 3.87Å; F50-I85 HydrophobicContact CD2-CD1 4.24Å
51	S	93.4	Very high	92.3	Very high	0 Å²	0	12.9 Å²	12.9	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-73.7	-43.9	174.7	-58.8	0	0	0	0	112.5	T47 F48 A49 T53 M54 F391	T47-S51 WeakPolarHBondContact O-CB 3.37Å; T47-S51 PolarHBondContact O-N 3.43Å; T47-S51 VanDerWaalsContact O-N 3.09Å; T47-S51 PolarHBondContact O-OG 2.98Å; F48-S51 WeakPolarHBondContact O-CB 3.48Å; F48-S51 PolarHBondContact O-N 2.8Å; A49-S51 PolarHBondContact O-N 2.96Å; S51-T53 VanDerWaalsContact C-N 3.29Å; S51-T53 PolarHBondContact O-N 3.01Å; S51-M54 WeakPolarHBondContact O-CB 3.34Å; S51-M54 PolarHBondContact O-N 3.48Å; S51-F391 WeakPolarHBondContact OG-CD2 3.43Å
52	C	92.8	Very high	92.1	Very high	8 Å²	8	12 Å²	12	5%	0.054	6%	0.063	C	C	.	.	H	α-helix	trans	-61.9	-38.9	173.4	-74.1	0	0	0	0	111.7	F17 F48 A49 M54 F55 E56	F17-C52 HydrophobicContact CB-CB 4.06Å; F17-C52 HydrophobicContact CD1-CB 3.77Å; F17-C52 HydrophobicContact CD2-CB 3.65Å; F17-C52 HydrophobicContact CE1-CB 4.07Å; F17-C52 HydrophobicContact CE2-CB 3.94Å; F17-C52 HydrophobicContact CG-CB 3.57Å; F17-C52 HydrophobicContact CZ-CB 4.15Å; F48-C52 WeakPolarHBondContact CE1-SG 3.38Å; F48-C52 WeakPolarHBondContact CZ-SG 3.46Å; F48-C52 PolarHBondContact O-N 3.42Å; A49-C52 PolarHBondContact O-N 3.19Å; A49-C52 VanDerWaalsContact O-N 3.15Å; C52-M54 VanDerWaalsContact C-N 3.27Å; C52-M54 PolarHBondContact O-N 3.46Å; C52-F55 WeakPolarHBondContact O-CB 3.43Å; C52-F55 PolarHBondContact O-N 2.88Å; C52-E56 PolarHBondContact O-N 3.17Å
53	T	93.7	Very high	91.8	Very high	5 Å²	5	13.9 Å²	13.9	3%	0.031	7%	0.071	C	C	.	.	H	α-helix	trans	-61.6	-33.1	175.9	-58.6	0	0	0	0	112.4	M10 Q14 A49 S51 F55 E56 L57 N78	M10-T53 HydrophobicContact CE-CG2 3.57Å; Q14-T53 PolarHBondContact OE1-OG1 2.85Å; A49-T53 PolarHBondContact O-N 3.04Å; A49-T53 PolarHBondContact O-OG1 2.9Å; S51-T53 VanDerWaalsContact C-N 3.29Å; S51-T53 PolarHBondContact O-N 3.01Å; T53-F55 VanDerWaalsContact C-N 3.29Å; T53-F55 PolarHBondContact O-N 3.4Å; T53-E56 PolarHBondContact O-N 3.11Å; T53-L57 HydrophobicContact CG2-CD1 4.29Å; T53-L57 HydrophobicContact CG2-CG 4.37Å; T53-L57 WeakPolarHBondContact O-CB 3.27Å; T53-L57 VanDerWaalsContact O-CG 3.25Å; T53-L57 WeakPolarHBondContact O-CG 3.43Å; T53-L57 PolarHBondContact O-N 3.21Å; T53-N78 WeakPolarHBondContact CB-OD1 3.25Å; T53-N78 VanDerWaalsContact CG2-OD1 3.27Å; T53-N78 WeakPolarHBondContact CG2-OD1 3.49Å
54	M	91.2	Very high	91.4	Very high	1 Å²	1	15.7 Å²	15.7	1%	0.005	9%	0.094	C	C	.	.	H	α-helix	trans	-60.2	-41.2	172.2	-65.3	-175.5	70.5	0	0	111.9	F50 S51 C52 I58 W75 N78 L79 I82 V392 V395	F50-M54 WeakPolarHBondContact O-CG 3.42Å; F50-M54 PolarHBondContact O-N 2.94Å; S51-M54 WeakPolarHBondContact O-CB 3.34Å; S51-M54 PolarHBondContact O-N 3.48Å; C52-M54 VanDerWaalsContact C-N 3.27Å; C52-M54 PolarHBondContact O-N 3.46Å; M54-I58 WeakPolarHBondContact O-CG1 3.36Å; M54-I58 PolarHBondContact O-N 2.76Å; M54-W75 HydrophobicContact CB-CH2 4.48Å; M54-W75 HydrophobicContact CB-CZ3 4.39Å; M54-W75 HydrophobicContact CE-CZ3 4.03Å; M54-W75 WeakPolarHBondContact O-CH2 3.44Å; M54-N78 WeakPolarHBondContact CG-ND2 3.47Å; M54-L79 HydrophobicContact CE-CD2 3.29Å; M54-L79 HydrophobicContact CE-CG 4.39Å; M54-L79 HydrophobicContact SD-CD2 4.11Å; M54-I82 HydrophobicContact SD-CG2 4.32Å; M54-V392 HydrophobicContact CE-CG2 4.46Å; M54-V392 HydrophobicContact SD-CG2 4.01Å; M54-V395 HydrophobicContact CB-CG2 3.96Å; M54-V395 HydrophobicContact CE-CB 3.87Å; M54-V395 HydrophobicContact CE-CG1 3.84Å; M54-V395 HydrophobicContact CE-CG2 3.9Å
55	F	90.5	Very high	90.9	Very high	3 Å²	3	18.4 Å²	18.4	1%	0.013	11%	0.11	C	C	.	.	H	α-helix	trans	-73.3	-37.7	178.2	-66.6	-49.8	0	0	0	112.8	C52 T53 L57 I58 I59 I352 I356 F391 V395 I398	C52-F55 WeakPolarHBondContact O-CB 3.43Å; C52-F55 PolarHBondContact O-N 2.88Å; T53-F55 VanDerWaalsContact C-N 3.29Å; T53-F55 PolarHBondContact O-N 3.4Å; F55-L57 VanDerWaalsContact C-N 3.3Å; F55-L57 PolarHBondContact O-N 3.15Å; F55-I58 HydrophobicContact CD1-CD1 4.28Å; F55-I58 WeakPolarHBondContact O-CB 3.4Å; F55-I58 PolarHBondContact O-N 3Å; F55-I59 PolarHBondContact O-N 3.47Å; F55-I352 HydrophobicContact CB-CD1 3.89Å; F55-I352 HydrophobicContact CB-CG1 4.05Å; F55-I352 HydrophobicContact CB-CG2 3.71Å; F55-I352 HydrophobicContact CD1-CB 4.46Å; F55-I352 HydrophobicContact CD1-CD1 4.11Å; F55-I352 HydrophobicContact CD1-CG1 3.6Å; F55-I352 HydrophobicContact CD1-CG2 4.24Å; F55-I352 HydrophobicContact CD2-CG2 3.86Å; F55-I352 HydrophobicContact CE1-CG1 4.16Å; F55-I352 HydrophobicContact CE2-CG2 4.47Å; F55-I352 HydrophobicContact CG-CB 4.4Å; F55-I352 HydrophobicContact CG-CD1 4.27Å; F55-I352 HydrophobicContact CG-CG1 3.9Å; F55-I352 HydrophobicContact CG-CG2 3.7Å; F55-I356 HydrophobicContact CD2-CD1 3.92Å; F55-I356 HydrophobicContact CD2-CG1 4.18Å; F55-I356 HydrophobicContact CE2-CD1 4.16Å; F55-I356 HydrophobicContact CE2-CG1 3.89Å; F55-F391 HydrophobicContact CE2-CB 4.5Å; F55-F391 AromaticContact CE2-CD1 3.31Å; F55-F391 HydrophobicContact CE2-CD1 3.31Å; F55-F391 AromaticContact CE2-CE1 3.6Å; F55-F391 HydrophobicContact CE2-CE1 3.6Å; F55-F391 HydrophobicContact CE2-CG 4.1Å; F55-F391 AromaticContact CZ-CD1 3.59Å; F55-F391 HydrophobicContact CZ-CD1 3.59Å; F55-F391 HydrophobicContact CZ-CE1 4.18Å; F55-F391 HydrophobicContact CZ-CG 4.43Å; F55-V395 HydrophobicContact CD1-CG2 3.93Å; F55-V395 HydrophobicContact CE1-CG2 3.72Å; F55-I398 HydrophobicContact CD1-CD1 4.25Å; F55-I398 HydrophobicContact CE1-CD1 3.76Å
56	E	91.6	Very high	90.7	Very high	27 Å²	27	19.4 Å²	19.4	13%	0.126	12%	0.115	C	C	.	.	H	α-helix	trans	-58.6	-44.2	172.2	-178.1	-179.1	-144.2	0	0	111.1	M10 S13 F17 C52 T53 I58 I59 F60	M10-E56 VanDerWaalsContact CE-OE2 3.27Å; M10-E56 WeakPolarHBondContact CE-OE2 3.5Å; S13-E56 VanDerWaalsContact CB-CD 3.45Å; S13-E56 WeakPolarHBondContact CB-OE1 3.41Å; S13-E56 WeakPolarHBondContact CB-OE2 3.33Å; S13-E56 VanDerWaalsContact OG-CD 3.27Å; S13-E56 PolarHBondContact OG-OE1 2.85Å; S13-E56 PolarHBondContact OG-OE2 2.92Å; F17-E56 HydrophobicContact CE2-CB 4.05Å; F17-E56 WeakPolarHBondContact CE2-OE2 3.47Å; F17-E56 HydrophobicContact CZ-CB 4.24Å; C52-E56 PolarHBondContact O-N 3.17Å; T53-E56 PolarHBondContact O-N 3.11Å; E56-I58 VanDerWaalsContact C-N 3.26Å; E56-I58 PolarHBondContact O-N 3.48Å; E56-I59 CarbonylContact O-C 3.59Å; E56-I59 WeakPolarHBondContact O-CA 3.31Å; E56-I59 WeakPolarHBondContact O-CB 3.35Å; E56-I59 PolarHBondContact O-N 3.04Å; E56-F60 HydrophobicContact CG-CD2 3.98Å; E56-F60 HydrophobicContact CG-CE1 4.11Å; E56-F60 HydrophobicContact CG-CE2 3.5Å; E56-F60 HydrophobicContact CG-CG 4.48Å; E56-F60 HydrophobicContact CG-CZ 3.57Å; E56-F60 WeakPolarHBondContact O-CG 3.29Å; E56-F60 PolarHBondContact O-N 2.97Å; E56-F60 VanDerWaalsContact OE1-CZ 3.22Å; E56-F60 WeakPolarHBondContact OE1-CZ 3.41Å
57	L	91.7	Very high	90.4	Very high	1 Å²	1	21.5 Å²	21.5	1%	0.005	13%	0.125	C	C	.	.	H	α-helix	trans	-63.1	-31.2	177	-72	172.2	0	0	0	112.7	M10 T53 F55 E61 H74 W75 N78	M10-L57 HydrophobicContact CE-CD2 4.13Å; M10-L57 HydrophobicContact CE-CG 4.44Å; M10-L57 HydrophobicContact SD-CD2 3.94Å; T53-L57 HydrophobicContact CG2-CD1 4.29Å; T53-L57 HydrophobicContact CG2-CG 4.37Å; T53-L57 WeakPolarHBondContact O-CB 3.27Å; T53-L57 VanDerWaalsContact O-CG 3.25Å; T53-L57 WeakPolarHBondContact O-CG 3.43Å; T53-L57 PolarHBondContact O-N 3.21Å; F55-L57 VanDerWaalsContact C-N 3.3Å; F55-L57 PolarHBondContact O-N 3.15Å; L57-E61 WeakPolarHBondContact O-CB 3.36Å; L57-E61 PolarHBondContact O-N 2.99Å; L57-H74 HydrophobicContact CD1-CB 4.49Å; L57-H74 HydrophobicContact CD2-CB 3.97Å; L57-W75 HydrophobicContact CB-CD2 4.08Å; L57-W75 VanDerWaalsContact CB-CE2 3.46Å; L57-W75 HydrophobicContact CB-CG 4.49Å; L57-W75 HydrophobicContact CB-CH2 4.31Å; L57-W75 HydrophobicContact CB-CZ2 3.6Å; L57-W75 HydrophobicContact CD1-CD2 3.93Å; L57-W75 HydrophobicContact CD1-CE3 4.29Å; L57-W75 HydrophobicContact CD1-CG 4.04Å; L57-N78 HydrophobicContact CD1-CB 4.21Å
58	I	89.1	Confident	90.1	Very high	0 Å²	0	24.8 Å²	24.8	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-66.7	-43.2	170.6	-65.1	173.4	0	0	0	110.6	M54 F55 E56 F60 E61 I62 W75 V348 V395 I398 M402 I410	M54-I58 WeakPolarHBondContact O-CG1 3.36Å; M54-I58 PolarHBondContact O-N 2.76Å; F55-I58 HydrophobicContact CD1-CD1 4.28Å; F55-I58 WeakPolarHBondContact O-CB 3.4Å; F55-I58 PolarHBondContact O-N 3Å; E56-I58 VanDerWaalsContact C-N 3.26Å; E56-I58 PolarHBondContact O-N 3.48Å; I58-F60 VanDerWaalsContact C-N 3.34Å; I58-F60 PolarHBondContact O-N 2.67Å; I58-E61 WeakPolarHBondContact O-CB 3.07Å; I58-E61 PolarHBondContact O-N 2.8Å; I58-E61 VanDerWaalsContact O-N 3.17Å; I58-I62 HydrophobicContact CG2-CD1 3.98Å; I58-I62 WeakPolarHBondContact O-CG1 3.25Å; I58-I62 PolarHBondContact O-N 3.36Å; I58-W75 HydrophobicContact CD1-CH2 4.36Å; I58-W75 HydrophobicContact CG1-CH2 3.73Å; I58-W75 HydrophobicContact CG1-CZ2 3.62Å; I58-V348 HydrophobicContact CG2-CG1 3.72Å; I58-V395 HydrophobicContact CD1-CB 4.41Å; I58-V395 HydrophobicContact CD1-CG1 4.05Å; I58-V395 HydrophobicContact CD1-CG2 3.93Å; I58-I398 HydrophobicContact CD1-CG2 4.18Å; I58-M402 HydrophobicContact CG2-CE 4.1Å; I58-M402 HydrophobicContact CG2-SD 3.55Å; I58-M402 VanDerWaalsContact CG2-SD 3.55Å; I58-I410 HydrophobicContact CG1-CD1 4.07Å
59	I	88.4	Confident	89.9	Confident	45 Å²	45	29.6 Å²	29.6	23%	0.231	18%	0.182	C	C	.	.	H	α-helix	trans	-62.3	-44.3	177.7	-70.8	165.7	0	0	0	110.5	F55 E56 E61 I62 L63 F345 I352	F55-I59 PolarHBondContact O-N 3.47Å; E56-I59 CarbonylContact O-C 3.59Å; E56-I59 WeakPolarHBondContact O-CA 3.31Å; E56-I59 WeakPolarHBondContact O-CB 3.35Å; E56-I59 PolarHBondContact O-N 3.04Å; I59-E61 VanDerWaalsContact C-N 3.27Å; I59-E61 PolarHBondContact O-N 3.42Å; I59-I62 PolarHBondContact O-N 2.8Å; I59-L63 HydrophobicContact CG2-CD1 3.7Å; I59-L63 HydrophobicContact CG2-CG 4.28Å; I59-L63 WeakPolarHBondContact O-CB 3.42Å; I59-L63 WeakPolarHBondContact O-CG 3.28Å; I59-L63 PolarHBondContact O-N 3.2Å; I59-F345 HydrophobicContact CG2-CD2 4.48Å; I59-F345 HydrophobicContact CG2-CE2 3.83Å; I59-I352 HydrophobicContact CD1-CD1 4.14Å; I59-I352 HydrophobicContact CG1-CD1 4.13Å
60	F	90.5	Very high	89.8	Confident	26 Å²	26	29.7 Å²	29.7	11%	0.114	18%	0.183	C	C	.	.	H	α-helix	trans	-65.7	-30	175	-67.6	-15.5	0	0	0	112.8	I9 M10 E56 I58 G64 V65 L66 R71	I9-F60 HydrophobicContact CG2-CZ 4.44Å; M10-F60 HydrophobicContact CE-CE2 4.44Å; M10-F60 HydrophobicContact SD-CD2 3.86Å; M10-F60 HydrophobicContact SD-CE2 3.57Å; M10-F60 VanDerWaalsContact SD-CE2 3.57Å; E56-F60 HydrophobicContact CG-CD2 3.98Å; E56-F60 HydrophobicContact CG-CE1 4.11Å; E56-F60 HydrophobicContact CG-CE2 3.5Å; E56-F60 HydrophobicContact CG-CG 4.48Å; E56-F60 HydrophobicContact CG-CZ 3.57Å; E56-F60 WeakPolarHBondContact O-CG 3.29Å; E56-F60 PolarHBondContact O-N 2.97Å; E56-F60 VanDerWaalsContact OE1-CZ 3.22Å; E56-F60 WeakPolarHBondContact OE1-CZ 3.41Å; I58-F60 VanDerWaalsContact C-N 3.34Å; I58-F60 PolarHBondContact O-N 2.67Å; F60-G64 PolarHBondContact O-N 3.11Å; F60-G64 VanDerWaalsContact O-N 3.08Å; F60-V65 HydrophobicContact CB-CB 4.33Å; F60-V65 HydrophobicContact CD1-CB 3.93Å; F60-V65 HydrophobicContact CD1-CG1 4.08Å; F60-V65 HydrophobicContact CE1-CG1 4.29Å; F60-V65 HydrophobicContact CG-CB 4.26Å; F60-V65 HydrophobicContact CG-CG1 4.46Å; F60-V65 PolarHBondContact O-N 3.38Å; F60-V65 VanDerWaalsContact O-N 3.07Å; F60-L66 HydrophobicContact CD2-CD1 3.5Å; F60-L66 VanDerWaalsContact CD2-CD1 3.5Å; F60-L66 HydrophobicContact CD2-CG 4.15Å; F60-L66 HydrophobicContact CE2-CD1 4.01Å; F60-L66 HydrophobicContact CG-CD1 4.3Å; F60-R71 PolarHBondContact O-NH1 3.4Å
61	E	88.1	Confident	89.6	Confident	8 Å²	8	29.1 Å²	29.1	4%	0.037	18%	0.18	C	C	.	.	H	α-helix	trans	-63.5	-50.1	171.8	-166.7	63.8	-169.4	0	0	111.5	L57 I58 I59 G64 R71 Y406 I409	L57-E61 WeakPolarHBondContact O-CB 3.36Å; L57-E61 PolarHBondContact O-N 2.99Å; I58-E61 WeakPolarHBondContact O-CB 3.07Å; I58-E61 PolarHBondContact O-N 2.8Å; I58-E61 VanDerWaalsContact O-N 3.17Å; I59-E61 VanDerWaalsContact C-N 3.27Å; I59-E61 PolarHBondContact O-N 3.42Å; E61-G64 PolarHBondContact O-N 3Å; E61-R71 PolarHBondContact O-NH1 3.43Å; E61-R71 WeakPolarHBondContact OE2-CD 3.26Å; E61-R71 IonicContact OE2-CZ 3.35Å; E61-R71 IonicContact OE2-NE 2.72Å; E61-R71 PolarHBondContact OE2-NE 2.87Å; E61-R71 IonicContact OE2-NH1 3.21Å; E61-R71 PolarHBondContact OE2-NH1 3.17Å; E61-R71 IonicContact OE2-NH2 3.42Å; E61-Y406 WeakPolarHBondContact CG-O 3.1Å; E61-I409 WeakPolarHBondContact OE2-CD1 3.25Å
62	I	85.4	Confident	89.5	Confident	1 Å²	1	32.7 Å²	32.7	1%	0.005	19%	0.194	C	C	.	.	H	α-helix	trans	-67.5	-40.8	-179	-62.7	166.9	0	0	0	111.8	I58 I59 G64 Q341 F345 V348 M402 Y406	I58-I62 HydrophobicContact CG2-CD1 3.98Å; I58-I62 WeakPolarHBondContact O-CG1 3.25Å; I58-I62 PolarHBondContact O-N 3.36Å; I59-I62 PolarHBondContact O-N 2.8Å; I62-G64 VanDerWaalsContact C-N 3.32Å; I62-Q341 HydrophobicContact CG2-CG 4.18Å; I62-Q341 PolarHBondContact O-NE2 3.37Å; I62-F345 HydrophobicContact CG2-CB 3.91Å; I62-V348 HydrophobicContact CD1-CB 3.98Å; I62-V348 HydrophobicContact CD1-CG1 4.03Å; I62-V348 HydrophobicContact CD1-CG2 4.01Å; I62-M402 HydrophobicContact CD1-SD 4.06Å; I62-M402 HydrophobicContact CG1-SD 4.34Å; I62-Y406 HydrophobicContact CG1-CG 4.45Å
63	L	86.5	Confident	89.5	Confident	78 Å²	78	36.9 Å²	36.9	41%	0.408	21%	0.211	S	C	.	.	H	α-helix	trans	-80.7	-10.9	-178.4	-66.6	178.9	0	0	0	113.5	I59 V65 F345	I59-L63 HydrophobicContact CG2-CD1 3.7Å; I59-L63 HydrophobicContact CG2-CG 4.28Å; I59-L63 WeakPolarHBondContact O-CB 3.42Å; I59-L63 WeakPolarHBondContact O-CG 3.28Å; I59-L63 PolarHBondContact O-N 3.2Å; L63-V65 VanDerWaalsContact C-N 3.27Å; L63-V65 HydrophobicContact CB-CG2 3.74Å; L63-V65 PolarHBondContact O-N 3.43Å; L63-F345 HydrophobicContact CD1-CD2 4.36Å; L63-F345 HydrophobicContact CD1-CE2 3.86Å; L63-F345 HydrophobicContact CD1-CZ 4.49Å; L63-F345 HydrophobicContact CD2-CD2 3.83Å; L63-F345 HydrophobicContact CD2-CE2 4.03Å; L63-F345 HydrophobicContact CD2-CG 4.26Å; L63-F345 HydrophobicContact CG-CD2 4.02Å; L63-F345 HydrophobicContact CG-CE2 4.04Å
64	G	84.9	Confident	89.5	Confident	54 Å²	54	37.2 Å²	37.2	56%	0.557	21%	0.212	S	C	*	.	T	Hydrogen-bonded Turn	trans	68.7	25.8	-175.2	0	0	0	0	0	113.5	F60 E61 I62	F60-G64 PolarHBondContact O-N 3.11Å; F60-G64 VanDerWaalsContact O-N 3.08Å; E61-G64 PolarHBondContact O-N 3Å; I62-G64 VanDerWaalsContact C-N 3.32Å
65	V	83.5	Confident	89.5	Confident	59 Å²	59	37.2 Å²	37.2	36%	0.358	21%	0.213	S	C	.	.			trans	-87.1	141	178.7	-179	0	0	0	0	108.7	F60 L63 R71	F60-V65 HydrophobicContact CB-CB 4.33Å; F60-V65 HydrophobicContact CD1-CB 3.93Å; F60-V65 HydrophobicContact CD1-CG1 4.08Å; F60-V65 HydrophobicContact CE1-CG1 4.29Å; F60-V65 HydrophobicContact CG-CB 4.26Å; F60-V65 HydrophobicContact CG-CG1 4.46Å; F60-V65 PolarHBondContact O-N 3.38Å; F60-V65 VanDerWaalsContact O-N 3.07Å; L63-V65 VanDerWaalsContact C-N 3.27Å; L63-V65 HydrophobicContact CB-CG2 3.74Å; L63-V65 PolarHBondContact O-N 3.43Å; V65-R71 WeakPolarHBondContact O-CD 3.29Å
66	L	88.6	Confident	89.6	Confident	20 Å²	20	42 Å²	42	11%	0.105	23%	0.233	C	C	.	.	S	Bend	trans	72	153.4	-169.9	-44.5	171.5	0	0	0	113.7	D6 I9 M10 F60 R71	D6-L66 HydrophobicContact CB-CB 4.45Å; D6-L66 HydrophobicContact CB-CD2 3.67Å; D6-L66 WeakPolarHBondContact OD1-CD2 3.41Å; I9-L66 HydrophobicContact CB-CD2 4.47Å; I9-L66 HydrophobicContact CD1-CD2 4.09Å; M10-L66 HydrophobicContact CG-CD1 4.11Å; M10-L66 HydrophobicContact SD-CD1 3.69Å; F60-L66 HydrophobicContact CD2-CD1 3.5Å; F60-L66 VanDerWaalsContact CD2-CD1 3.5Å; F60-L66 HydrophobicContact CD2-CG 4.15Å; F60-L66 HydrophobicContact CE2-CD1 4.01Å; F60-L66 HydrophobicContact CG-CD1 4.3Å; L66-R71 HydrophobicContact CB-CG 3.78Å; L66-R71 HydrophobicContact CD1-CG 4.32Å
67	N	90.1	Very high	89.6	Confident	79 Å²	79	44.5 Å²	44.5	42%	0.422	25%	0.246	S	C	.	.			trans	-67.8	144.1	174.7	-71.5	-59.2	0	0	0	111.5	S2 D6 S69 S70 R71	S2-N67 WeakPolarHBondContact CB-ND2 3.44Å; S2-N67 PolarHBondContact OG-ND2 2.86Å; S2-N67 VanDerWaalsContact OG-ND2 3.08Å; D6-N67 PolarHBondContact OD2-N 3.41Å; D6-N67 VanDerWaalsContact OD2-N 3.13Å; D6-N67 PolarHBondContact OD2-ND2 3.11Å; N67-S69 VanDerWaalsContact C-N 3.3Å; N67-S69 PolarHBondContact O-N 3.22Å; N67-S70 WeakPolarHBondContact O-CA 3.38Å; N67-S70 WeakPolarHBondContact O-CB 3.44Å; N67-S70 PolarHBondContact O-N 3.35Å; N67-R71 PolarHBondContact O-N 2.83Å
68	S	88.2	Confident	89.8	Confident	69 Å²	69	44.7 Å²	44.7	48%	0.483	25%	0.247	S	C	.	.	H	α-helix	trans	-53.8	-41.9	179.6	-60.9	0	0	0	0	113.7	S70 R71 Y72	S68-S70 VanDerWaalsContact C-N 3.32Å; S68-S70 PolarHBondContact O-N 2.87Å; S68-R71 PolarHBondContact O-N 2.83Å; S68-R71 PolarHBondContact OG-NH2 3.25Å; S68-R71 VanDerWaalsContact OG-NH2 3.13Å; S68-Y72 WeakPolarHBondContact O-CB 3.44Å; S68-Y72 PolarHBondContact O-N 2.93Å
69	S	90	Very high	89.9	Confident	103 Å²	103	44.7 Å²	44.7	72%	0.72	25%	0.247	S	C	*	.	H	α-helix	trans	-65.6	-34.7	176.3	-50	0	0	0	0	112.8	N67 F73	N67-S69 VanDerWaalsContact C-N 3.3Å; N67-S69 PolarHBondContact O-N 3.22Å; S69-F73 PolarHBondContact O-N 2.88Å; S69-F73 VanDerWaalsContact O-N 3.12Å
70	S	91.8	Very high	90.1	Very high	3 Å²	3	45 Å²	45	2%	0.021	25%	0.253	C	S	.	.	H	α-helix	trans	-70.4	-46.2	176.5	-166.6	0	0	0	0	110.9	D6 N67 S68 Y72 F73 H74	D6-S70 WeakPolarHBondContact CB-OG 3.42Å; D6-S70 VanDerWaalsContact OD2-CB 3.23Å; D6-S70 WeakPolarHBondContact OD2-CB 3.48Å; D6-S70 PolarHBondContact OD2-OG 2.92Å; N67-S70 WeakPolarHBondContact O-CA 3.38Å; N67-S70 WeakPolarHBondContact O-CB 3.44Å; N67-S70 PolarHBondContact O-N 3.35Å; S68-S70 VanDerWaalsContact C-N 3.32Å; S68-S70 PolarHBondContact O-N 2.87Å; S70-Y72 VanDerWaalsContact C-N 3.32Å; S70-Y72 PolarHBondContact O-N 3.13Å; S70-F73 PolarHBondContact O-N 3.44Å; S70-H74 PolarHBondContact O-CD2 3.23Å; S70-H74 PolarHBondContact O-N 2.72Å; S70-H74 PolarHBondContact OG-CD2 2.86Å
71	R	91.4	Very high	90.3	Very high	22 Å²	22	45.8 Å²	45.8	8%	0.083	26%	0.259	C	S	.	.	H	α-helix	trans	-55.1	-47.6	173.6	-68.6	-170.3	-69.5	-174.1	11.2	111.5	F60 E61 V65 L66 N67 S68 F73 H74 W75 I409	F60-R71 PolarHBondContact O-NH1 3.4Å; E61-R71 PolarHBondContact O-NH1 3.43Å; E61-R71 WeakPolarHBondContact OE2-CD 3.26Å; E61-R71 IonicContact OE2-CZ 3.35Å; E61-R71 IonicContact OE2-NE 2.72Å; E61-R71 PolarHBondContact OE2-NE 2.87Å; E61-R71 IonicContact OE2-NH1 3.21Å; E61-R71 PolarHBondContact OE2-NH1 3.17Å; E61-R71 IonicContact OE2-NH2 3.42Å; V65-R71 WeakPolarHBondContact O-CD 3.29Å; L66-R71 HydrophobicContact CB-CG 3.78Å; L66-R71 HydrophobicContact CD1-CG 4.32Å; N67-R71 PolarHBondContact O-N 2.83Å; S68-R71 PolarHBondContact O-N 2.83Å; S68-R71 PolarHBondContact OG-NH2 3.25Å; S68-R71 VanDerWaalsContact OG-NH2 3.13Å; R71-F73 PolarHBondContact O-N 3.1Å; R71-H74 PolarHBondContact O-N 3.08Å; R71-W75 WeakPolarHBondContact O-CB 3.33Å; R71-W75 VanDerWaalsContact O-CD1 3.31Å; R71-W75 PolarHBondContact O-N 3.05Å; R71-I409 HydrophobicContact CB-CD1 3.84Å
72	Y	91	Very high	90.6	Very high	74 Å²	74	45.4 Å²	45.4	29%	0.29	26%	0.257	S	S	.	.	H	α-helix	trans	-58.4	-46.7	177.5	179.8	-91.6	0	0	0	112.2	S68 S70 W75 K76 I409 E412 V413	S68-Y72 WeakPolarHBondContact O-CB 3.44Å; S68-Y72 PolarHBondContact O-N 2.93Å; S70-Y72 VanDerWaalsContact C-N 3.32Å; S70-Y72 PolarHBondContact O-N 3.13Å; Y72-W75 PolarHBondContact O-N 2.97Å; Y72-K76 HydrophobicContact CE1-CD 4.42Å; Y72-K76 PolarHBondContact O-N 3.23Å; Y72-I409 HydrophobicContact CD2-CG2 4.22Å; Y72-E412 HydrophobicContact CE2-CB 4.39Å; Y72-E412 HydrophobicContact CE2-CG 3.93Å; Y72-E412 WeakPolarHBondContact CE2-OE1 3.34Å; Y72-V413 HydrophobicContact CD2-CG2 3.7Å; Y72-V413 HydrophobicContact CE2-CG2 3.63Å
73	F	93.1	Very high	91	Very high	96 Å²	96	45.5 Å²	45.5	42%	0.421	26%	0.258	S	S	.	.	H	α-helix	trans	-60.6	-48.4	176.9	175.2	-97.3	0	0	0	112	F3 S69 S70 R71 W75 K76 M77	F3-F73 HydrophobicContact CE2-CB 4.23Å; F3-F73 AromaticContact CE2-CD1 3.7Å; F3-F73 HydrophobicContact CE2-CD1 3.7Å; F3-F73 HydrophobicContact CE2-CE1 4.31Å; F3-F73 HydrophobicContact CE2-CG 4.05Å; F3-F73 AromaticContact CZ-CD1 3.55Å; F3-F73 HydrophobicContact CZ-CD1 3.55Å; F3-F73 AromaticContact CZ-CE1 3.69Å; F3-F73 HydrophobicContact CZ-CE1 3.69Å; F3-F73 HydrophobicContact CZ-CG 4.13Å; F3-F73 HydrophobicContact CZ-CZ 4.36Å; S69-F73 PolarHBondContact O-N 2.88Å; S69-F73 VanDerWaalsContact O-N 3.12Å; S70-F73 PolarHBondContact O-N 3.44Å; R71-F73 PolarHBondContact O-N 3.1Å; F73-W75 PolarHBondContact O-N 3.24Å; F73-K76 PolarHBondContact O-N 3.18Å; F73-M77 HydrophobicContact CD1-CE 4.27Å; F73-M77 HydrophobicContact CE1-CE 3.48Å; F73-M77 VanDerWaalsContact CE1-CE 3.48Å; F73-M77 HydrophobicContact CZ-CE 4.09Å; F73-M77 WeakPolarHBondContact O-CB 3.45Å; F73-M77 PolarHBondContact O-N 3.24Å
74	H	93.6	Very high	91.4	Very high	12 Å²	12	45.7 Å²	45.7	6%	0.056	26%	0.259	C	S	.	.	H	α-helix	trans	-65.2	-38.5	179.7	-73.8	-64.3	0	0	0	112.4	S7 L57 S70 R71 N78	S7-H74 PolarHBondContact OG-NE2 3.49Å; L57-H74 HydrophobicContact CD1-CB 4.49Å; L57-H74 HydrophobicContact CD2-CB 3.97Å; S70-H74 PolarHBondContact O-CD2 3.23Å; S70-H74 PolarHBondContact O-N 2.72Å; S70-H74 PolarHBondContact OG-CD2 2.86Å; R71-H74 PolarHBondContact O-N 3.08Å; H74-N78 WeakPolarHBondContact O-CB 3.32Å; H74-N78 PolarHBondContact O-N 3.02Å
75	W	91.8	Very high	91.9	Very high	2 Å²	2	43.6 Å²	43.6	1%	0.008	24%	0.235	C	C	.	.	H	α-helix	trans	-58.1	-52	171.8	-95.1	111.9	0	0	0	112.1	M54 L57 I58 R71 Y72 F73 M77 N78 L79 V395 I409 I410 V413	M54-W75 HydrophobicContact CB-CH2 4.48Å; M54-W75 HydrophobicContact CB-CZ3 4.39Å; M54-W75 HydrophobicContact CE-CZ3 4.03Å; M54-W75 WeakPolarHBondContact O-CH2 3.44Å; L57-W75 HydrophobicContact CB-CD2 4.08Å; L57-W75 VanDerWaalsContact CB-CE2 3.46Å; L57-W75 HydrophobicContact CB-CG 4.49Å; L57-W75 HydrophobicContact CB-CH2 4.31Å; L57-W75 HydrophobicContact CB-CZ2 3.6Å; L57-W75 HydrophobicContact CD1-CD2 3.93Å; L57-W75 HydrophobicContact CD1-CE3 4.29Å; L57-W75 HydrophobicContact CD1-CG 4.04Å; I58-W75 HydrophobicContact CD1-CH2 4.36Å; I58-W75 HydrophobicContact CG1-CH2 3.73Å; I58-W75 HydrophobicContact CG1-CZ2 3.62Å; R71-W75 WeakPolarHBondContact O-CB 3.33Å; R71-W75 VanDerWaalsContact O-CD1 3.31Å; R71-W75 PolarHBondContact O-N 3.05Å; Y72-W75 PolarHBondContact O-N 2.97Å; F73-W75 PolarHBondContact O-N 3.24Å; W75-M77 PolarHBondContact O-N 3.1Å; W75-N78 PolarHBondContact O-N 3.08Å; W75-L79 HydrophobicContact CE3-CD1 4.22Å; W75-L79 HydrophobicContact CE3-CG 4.34Å; W75-L79 WeakPolarHBondContact O-CB 3.46Å; W75-L79 WeakPolarHBondContact O-CG 3.3Å; W75-L79 PolarHBondContact O-N 3.22Å; W75-V395 HydrophobicContact CH2-CG1 3.9Å; W75-V395 HydrophobicContact CZ3-CG1 4.13Å; W75-I409 HydrophobicContact CB-CG2 4.39Å; W75-I409 HydrophobicContact CG-CG2 4.13Å; W75-I410 HydrophobicContact CH2-CG1 4.36Å; W75-I410 HydrophobicContact CZ2-CD1 4Å; W75-I410 HydrophobicContact CZ2-CG1 3.82Å; W75-V413 HydrophobicContact CB-CG1 4.3Å; W75-V413 HydrophobicContact CB-CG2 4.03Å
76	K	91.9	Very high	92.4	Very high	104 Å²	104	40.8 Å²	40.8	45%	0.452	22%	0.218	S	C	.	.	H	α-helix	trans	-63.6	-42.7	-179.2	-173.1	173.3	-176.7	171.5	0	111.9	Y72 F73 C80	Y72-K76 HydrophobicContact CE1-CD 4.42Å; Y72-K76 PolarHBondContact O-N 3.23Å; F73-K76 PolarHBondContact O-N 3.18Å; K76-C80 VanDerWaalsContact O-CB 3.32Å; K76-C80 WeakPolarHBondContact O-CB 3.44Å; K76-C80 PolarHBondContact O-N 2.92Å
77	M	93.2	Very high	92.6	Very high	78 Å²	78	39.9 Å²	39.9	38%	0.384	21%	0.213	S	C	.	.	H	α-helix	trans	-64.3	-49.8	177.1	-174.7	-130.3	-68.5	0	0	111.2	F73 W75 L79 C80 V81	F73-M77 HydrophobicContact CD1-CE 4.27Å; F73-M77 HydrophobicContact CE1-CE 3.48Å; F73-M77 VanDerWaalsContact CE1-CE 3.48Å; F73-M77 HydrophobicContact CZ-CE 4.09Å; F73-M77 WeakPolarHBondContact O-CB 3.45Å; F73-M77 PolarHBondContact O-N 3.24Å; W75-M77 PolarHBondContact O-N 3.1Å; M77-L79 VanDerWaalsContact C-N 3.33Å; M77-L79 PolarHBondContact O-N 3.5Å; M77-C80 WeakPolarHBondContact O-CB 3.2Å; M77-C80 PolarHBondContact O-N 3.34Å; M77-V81 WeakPolarHBondContact O-CG2 3.36Å; M77-V81 PolarHBondContact O-N 3.07Å
78	N	94.3	Very high	92.8	Very high	5 Å²	5	38.8 Å²	38.8	3%	0.027	21%	0.205	C	C	.	.	H	α-helix	trans	-60.2	-44.2	-179	-169.7	88.3	0	0	0	111.3	F50 T53 M54 L57 H74 W75 V81 I82	F50-N78 WeakPolarHBondContact CD1-OD1 3.48Å; F50-N78 PolarHBondContact O-ND2 3.2Å; F50-N78 PolarHBondContact O-OD1 2.94Å; T53-N78 WeakPolarHBondContact CB-OD1 3.25Å; T53-N78 VanDerWaalsContact CG2-OD1 3.27Å; T53-N78 WeakPolarHBondContact CG2-OD1 3.49Å; M54-N78 WeakPolarHBondContact CG-ND2 3.47Å; L57-N78 HydrophobicContact CD1-CB 4.21Å; H74-N78 WeakPolarHBondContact O-CB 3.32Å; H74-N78 PolarHBondContact O-N 3.02Å; W75-N78 PolarHBondContact O-N 3.08Å; N78-V81 PolarHBondContact O-N 3.33Å; N78-I82 WeakPolarHBondContact O-CG2 3.44Å; N78-I82 PolarHBondContact O-N 3.01Å
79	L	92.1	Very high	93	Very high	1 Å²	1	40.4 Å²	40.4	1%	0.005	21%	0.206	C	C	.	.	H	α-helix	trans	-64.4	-42.4	175.4	-77.5	177	0	0	0	112.9	M54 W75 M77 V81 I82 L83 I147 V413 L414	M54-L79 HydrophobicContact CE-CD2 3.29Å; M54-L79 HydrophobicContact CE-CG 4.39Å; M54-L79 HydrophobicContact SD-CD2 4.11Å; W75-L79 HydrophobicContact CE3-CD1 4.22Å; W75-L79 HydrophobicContact CE3-CG 4.34Å; W75-L79 WeakPolarHBondContact O-CB 3.46Å; W75-L79 WeakPolarHBondContact O-CG 3.3Å; W75-L79 PolarHBondContact O-N 3.22Å; M77-L79 VanDerWaalsContact C-N 3.33Å; M77-L79 PolarHBondContact O-N 3.5Å; L79-V81 VanDerWaalsContact C-N 3.33Å; L79-V81 PolarHBondContact O-N 2.99Å; L79-I82 HydrophobicContact CD2-CG2 4.27Å; L79-I82 WeakPolarHBondContact O-CG2 3.35Å; L79-L83 VanDerWaalsContact O-CB 3.25Å; L79-L83 WeakPolarHBondContact O-CB 3.1Å; L79-L83 WeakPolarHBondContact O-CD1 3.05Å; L79-L83 WeakPolarHBondContact O-CG 3.47Å; L79-L83 PolarHBondContact O-N 2.63Å; L79-I147 HydrophobicContact CD1-CD1 3.81Å; L79-I147 HydrophobicContact CD2-CD1 3.48Å; L79-I147 VanDerWaalsContact CD2-CD1 3.48Å; L79-I147 HydrophobicContact CG-CD1 4.16Å; L79-V413 HydrophobicContact CD1-CG1 3.35Å; L79-L414 HydrophobicContact CD1-CD2 4.16Å
80	C	92.7	Very high	93.3	Very high	52 Å²	52	35.5 Å²	35.5	35%	0.351	17%	0.172	S	C	.	.	H	α-helix	trans	-58.9	-47.7	175.4	-174.4	0	0	0	0	110.9	K76 M77 L83 L84	K76-C80 VanDerWaalsContact O-CB 3.32Å; K76-C80 WeakPolarHBondContact O-CB 3.44Å; K76-C80 PolarHBondContact O-N 2.92Å; M77-C80 WeakPolarHBondContact O-CB 3.2Å; M77-C80 PolarHBondContact O-N 3.34Å; C80-L83 PolarHBondContact O-N 3.28Å; C80-L84 WeakPolarHBondContact O-CB 3.41Å; C80-L84 VanDerWaalsContact O-CG 3.27Å; C80-L84 WeakPolarHBondContact O-CG 3.3Å; C80-L84 PolarHBondContact O-N 3.38Å
81	V	94.6	Very high	93.4	Very high	41 Å²	41	35.6 Å²	35.6	25%	0.248	17%	0.172	C	C	.	.	H	α-helix	trans	-66.8	-47.7	-178	177.1	0	0	0	0	111.9	F50 M77 N78 L79 L83 L84 I85	F50-V81 HydrophobicContact CD1-CB 4.01Å; F50-V81 HydrophobicContact CD1-CG1 3.9Å; F50-V81 HydrophobicContact CD2-CG1 4Å; F50-V81 HydrophobicContact CE1-CB 3.69Å; F50-V81 HydrophobicContact CE1-CG1 3.56Å; F50-V81 HydrophobicContact CE1-CG2 4.13Å; F50-V81 HydrophobicContact CE2-CG1 3.63Å; F50-V81 HydrophobicContact CG-CG1 4.16Å; F50-V81 HydrophobicContact CZ-CB 4.05Å; F50-V81 HydrophobicContact CZ-CG1 3.43Å; F50-V81 VanDerWaalsContact CZ-CG1 3.43Å; F50-V81 HydrophobicContact CZ-CG2 4.36Å; M77-V81 WeakPolarHBondContact O-CG2 3.36Å; M77-V81 PolarHBondContact O-N 3.07Å; N78-V81 PolarHBondContact O-N 3.33Å; L79-V81 VanDerWaalsContact C-N 3.33Å; L79-V81 PolarHBondContact O-N 2.99Å; V81-L83 VanDerWaalsContact C-N 3.3Å; V81-L83 PolarHBondContact O-N 3Å; V81-L84 PolarHBondContact O-N 3.48Å; V81-I85 HydrophobicContact CG1-CD1 3.7Å; V81-I85 HydrophobicContact CG1-CG1 4.38Å; V81-I85 VanDerWaalsContact O-CG1 3.26Å; V81-I85 WeakPolarHBondContact O-CG1 3.31Å; V81-I85 PolarHBondContact O-N 3.35Å
82	I	94.3	Very high	93.6	Very high	0 Å²	0	37.2 Å²	37.2	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-63.4	-37.8	179.6	-166	66.5	0	0	0	111.4	T47 F50 M54 N78 L79 I85 L86 V392	T47-I82 HydrophobicContact CG2-CD1 4.02Å; F50-I82 HydrophobicContact CB-CB 4.36Å; F50-I82 HydrophobicContact CB-CD1 3.87Å; M54-I82 HydrophobicContact SD-CG2 4.32Å; N78-I82 WeakPolarHBondContact O-CG2 3.44Å; N78-I82 PolarHBondContact O-N 3.01Å; L79-I82 HydrophobicContact CD2-CG2 4.27Å; L79-I82 WeakPolarHBondContact O-CG2 3.35Å; I82-I85 PolarHBondContact O-N 2.85Å; I82-L86 HydrophobicContact CD1-CD1 4.4Å; I82-L86 HydrophobicContact CD1-CG 4.46Å; I82-L86 HydrophobicContact CG1-CD1 3.87Å; I82-L86 HydrophobicContact CG1-CG 4.32Å; I82-L86 WeakPolarHBondContact O-CB 3.33Å; I82-L86 VanDerWaalsContact O-CG 3.26Å; I82-L86 WeakPolarHBondContact O-CG 3.47Å; I82-L86 PolarHBondContact O-N 3.32Å; I82-V392 HydrophobicContact CG1-CG2 4.25Å; I82-V392 HydrophobicContact CG2-CG2 4.24Å
83	L	93.7	Very high	93.7	Very high	3 Å²	3	37.1 Å²	37.1	2%	0.016	18%	0.18	C	C	.	.	H	α-helix	trans	-68.3	-40.8	176.1	-69.2	174.8	0	0	0	111.9	L79 C80 V81 I85 L86 V87 I143 L146 I147 V150	L79-L83 VanDerWaalsContact O-CB 3.25Å; L79-L83 WeakPolarHBondContact O-CB 3.1Å; L79-L83 WeakPolarHBondContact O-CD1 3.05Å; L79-L83 WeakPolarHBondContact O-CG 3.47Å; L79-L83 PolarHBondContact O-N 2.63Å; C80-L83 PolarHBondContact O-N 3.28Å; V81-L83 VanDerWaalsContact C-N 3.3Å; V81-L83 PolarHBondContact O-N 3Å; L83-I85 VanDerWaalsContact C-N 3.28Å; L83-I85 PolarHBondContact O-N 2.91Å; L83-L86 PolarHBondContact O-N 2.69Å; L83-V87 VanDerWaalsContact O-CB 3.27Å; L83-V87 WeakPolarHBondContact O-CB 3.34Å; L83-V87 WeakPolarHBondContact O-CG2 3.33Å; L83-V87 PolarHBondContact O-N 3.41Å; L83-I143 HydrophobicContact CD1-CG2 3.84Å; L83-L146 HydrophobicContact CB-CD2 3.74Å; L83-L146 HydrophobicContact CB-CG 4.23Å; L83-L146 HydrophobicContact CD1-CB 4.23Å; L83-L146 HydrophobicContact CD1-CD2 4.28Å; L83-L146 HydrophobicContact CD1-CG 4.31Å; L83-L146 HydrophobicContact CD2-CG 4.17Å; L83-L146 HydrophobicContact CG-CD2 4.43Å; L83-L146 HydrophobicContact CG-CG 4.47Å; L83-I147 HydrophobicContact CD1-CB 4.2Å; L83-I147 HydrophobicContact CD1-CD1 4.36Å; L83-I147 HydrophobicContact CD1-CG1 4.38Å; L83-I147 HydrophobicContact CD2-CB 4.38Å; L83-I147 HydrophobicContact CD2-CG1 4.24Å; L83-V150 HydrophobicContact CD2-CB 4.27Å; L83-V150 HydrophobicContact CD2-CG2 3.93Å
84	L	94	Very high	93.7	Very high	82 Å²	82	33.5 Å²	33.5	43%	0.429	16%	0.164	S	C	.	.	H	α-helix	trans	-59.7	-41.7	173.9	-76.8	173.7	0	0	0	111.6	C80 V81 F88 M89	C80-L84 WeakPolarHBondContact O-CB 3.41Å; C80-L84 VanDerWaalsContact O-CG 3.27Å; C80-L84 WeakPolarHBondContact O-CG 3.3Å; C80-L84 PolarHBondContact O-N 3.38Å; V81-L84 PolarHBondContact O-N 3.48Å; L84-F88 HydrophobicContact CD2-CD2 3.84Å; L84-F88 HydrophobicContact CD2-CE2 3.95Å; L84-F88 WeakPolarHBondContact O-CB 3.43Å; L84-F88 PolarHBondContact O-N 2.86Å; L84-M89 PolarHBondContact O-N 3.17Å
85	I	95.1	Very high	93.7	Very high	10 Å²	10	32.9 Å²	32.9	5%	0.051	16%	0.162	C	C	.	.	I	π-helix	trans	-65.3	-50.5	177.3	-67.9	165.9	0	0	0	110.8	V46 T47 F50 V81 I82 L83 M89 V90	V46-I85 HydrophobicContact CG1-CD1 3.54Å; T47-I85 WeakPolarHBondContact OG1-CG2 3.22Å; F50-I85 HydrophobicContact CD2-CD1 4.24Å; V81-I85 HydrophobicContact CG1-CD1 3.7Å; V81-I85 HydrophobicContact CG1-CG1 4.38Å; V81-I85 VanDerWaalsContact O-CG1 3.26Å; V81-I85 WeakPolarHBondContact O-CG1 3.31Å; V81-I85 PolarHBondContact O-N 3.35Å; I82-I85 PolarHBondContact O-N 2.85Å; L83-I85 VanDerWaalsContact C-N 3.28Å; L83-I85 PolarHBondContact O-N 2.91Å; I85-M89 HydrophobicContact CG1-SD 4.17Å; I85-M89 PolarHBondContact O-N 3.38Å; I85-V90 HydrophobicContact CG2-CG2 3.68Å; I85-V90 WeakPolarHBondContact O-CB 3.44Å; I85-V90 WeakPolarHBondContact O-CG2 3.41Å; I85-V90 PolarHBondContact O-N 3.48Å
86	L	95.1	Very high	93.7	Very high	0 Å²	0	35.2 Å²	35.2	0%	0	17%	0.171	C	C	.	.	I	π-helix	trans	-73.2	-28.9	-173.7	-69.3	173.5	0	0	0	114.4	T47 I82 L83 P91 V150 Q385 G388 V392	T47-L86 HydrophobicContact CG2-CD2 4.19Å; I82-L86 HydrophobicContact CD1-CD1 4.4Å; I82-L86 HydrophobicContact CD1-CG 4.46Å; I82-L86 HydrophobicContact CG1-CD1 3.87Å; I82-L86 HydrophobicContact CG1-CG 4.32Å; I82-L86 WeakPolarHBondContact O-CB 3.33Å; I82-L86 VanDerWaalsContact O-CG 3.26Å; I82-L86 WeakPolarHBondContact O-CG 3.47Å; I82-L86 PolarHBondContact O-N 3.32Å; L83-L86 PolarHBondContact O-N 2.69Å; L86-P91 WeakPolarHBondContact O-CD 3.1Å; L86-P91 VanDerWaalsContact O-CG 3.31Å; L86-P91 WeakPolarHBondContact O-CG 3.25Å; L86-V150 HydrophobicContact CD1-CG1 4.19Å; L86-Q385 PolarHBondContact O-NE2 3.14Å; L86-Q385 PolarHBondContact O-OE1 3.14Å; L86-Q385 VanDerWaalsContact O-OE1 3.13Å; L86-G388 VanDerWaalsContact CD1-C 3.49Å; L86-V392 HydrophobicContact CD1-CG2 4.05Å
87	V	93.4	Very high	93.6	Very high	1 Å²	1	30.4 Å²	30.4	1%	0.006	15%	0.15	C	C	.	.	I	π-helix	trans	-96.8	-40.5	-174.9	173.7	0	0	0	0	110.7	L83 P91 M121 F124 W125 L146 V150	L83-V87 VanDerWaalsContact O-CB 3.27Å; L83-V87 WeakPolarHBondContact O-CB 3.34Å; L83-V87 WeakPolarHBondContact O-CG2 3.33Å; L83-V87 PolarHBondContact O-N 3.41Å; V87-P91 WeakPolarHBondContact O-CG 3.5Å; V87-M121 HydrophobicContact CG1-CE 4.33Å; V87-M121 HydrophobicContact CG1-SD 3.96Å; V87-F124 HydrophobicContact CG1-CD1 4.41Å; V87-F124 HydrophobicContact CG1-CE1 4.14Å; V87-F124 HydrophobicContact CG2-CE1 4.23Å; V87-F124 HydrophobicContact CG2-CZ 3.95Å; V87-W125 HydrophobicContact CG1-CZ3 4.43Å; V87-L146 HydrophobicContact CB-CD1 4.08Å; V87-L146 HydrophobicContact CB-CD2 4.39Å; V87-L146 HydrophobicContact CG1-CD1 3.83Å; V87-L146 HydrophobicContact CG2-CD1 3.34Å; V87-L146 HydrophobicContact CG2-CD2 3.97Å; V87-L146 HydrophobicContact CG2-CG 3.73Å; V87-V150 HydrophobicContact CG2-CG2 3.91Å
88	F	92.9	Very high	93.5	Very high	56 Å²	56	29.7 Å²	29.7	25%	0.246	15%	0.147	C	C	.	.	I	π-helix	trans	-104.8	-58.2	-172.8	-56.2	-94.8	0	0	0	111.2	L84 F92 W117 M121 L146	L84-F88 HydrophobicContact CD2-CD2 3.84Å; L84-F88 HydrophobicContact CD2-CE2 3.95Å; L84-F88 WeakPolarHBondContact O-CB 3.43Å; L84-F88 PolarHBondContact O-N 2.86Å; F88-F92 VanDerWaalsContact O-CB 3.23Å; F88-F92 WeakPolarHBondContact O-CB 3.41Å; F88-F92 PolarHBondContact O-N 2.86Å; F88-W117 HydrophobicContact CD1-CH2 4.46Å; F88-W117 AromaticContact CD1-CZ2 3.78Å; F88-W117 HydrophobicContact CD1-CZ2 3.78Å; F88-W117 PolarHBondContact O-NE1 3.4Å; F88-W117 VanDerWaalsContact O-NE1 3.16Å; F88-M121 HydrophobicContact CD1-CE 3.75Å; F88-M121 HydrophobicContact CD1-SD 4.49Å; F88-M121 HydrophobicContact CE1-CE 3.34Å; F88-M121 HydrophobicContact CZ-CE 4.07Å; F88-L146 HydrophobicContact CE2-CD2 4.33Å
89	M	94.1	Very high	93.3	Very high	103 Å²	103	29.8 Å²	29.8	51%	0.507	15%	0.147	S	C	.	.	I	π-helix	trans	-69.3	-56.5	-170	-63.6	-170	160.8	0	0	113.1	L84 I85 F92 Y93	L84-M89 PolarHBondContact O-N 3.17Å; I85-M89 HydrophobicContact CG1-SD 4.17Å; I85-M89 PolarHBondContact O-N 3.38Å; M89-F92 WeakPolarHBondContact O-CB 3.27Å; M89-F92 PolarHBondContact O-N 3.37Å; M89-Y93 WeakPolarHBondContact O-CD2 3.32Å; M89-Y93 PolarHBondContact O-N 2.9Å
90	V	95	Very high	93	Very high	0 Å²	0	31.3 Å²	31.3	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-61.2	-48.7	-174.7	174.9	0	0	0	0	111.5	I43 I85 F92 Y93 I94 L381 Q385	I43-V90 HydrophobicContact CG2-CG2 3.58Å; I85-V90 HydrophobicContact CG2-CG2 3.68Å; I85-V90 WeakPolarHBondContact O-CB 3.44Å; I85-V90 WeakPolarHBondContact O-CG2 3.41Å; I85-V90 PolarHBondContact O-N 3.48Å; V90-F92 VanDerWaalsContact C-N 3.29Å; V90-F92 PolarHBondContact O-N 3.25Å; V90-Y93 PolarHBondContact O-N 2.98Å; V90-I94 HydrophobicContact CG1-CD1 3.72Å; V90-I94 HydrophobicContact CG1-CG1 4.28Å; V90-I94 VanDerWaalsContact O-CG1 3.31Å; V90-I94 WeakPolarHBondContact O-CG1 3.33Å; V90-I94 PolarHBondContact O-N 3.21Å; V90-L381 WeakPolarHBondContact CG1-O 3.5Å; V90-Q385 VanDerWaalsContact CB-OE1 3.26Å; V90-Q385 HydrophobicContact CG1-CB 3.85Å; V90-Q385 HydrophobicContact CG1-CG 4.47Å
91	P	95	Very high	92.6	Very high	5 Å²	5	33 Å²	33	3%	0.032	16%	0.164	C	C	.	.	H	α-helix	trans	-61.5	-35.6	177.3	-26.4	38.7	0	0	0	113.4	L86 V87 I94 G95 F120	L86-P91 WeakPolarHBondContact O-CD 3.1Å; L86-P91 VanDerWaalsContact O-CG 3.31Å; L86-P91 WeakPolarHBondContact O-CG 3.25Å; V87-P91 WeakPolarHBondContact O-CG 3.5Å; P91-I94 PolarHBondContact O-N 3.02Å; P91-G95 PolarHBondContact O-N 3.22Å; P91-F120 HydrophobicContact CB-CD1 3.45Å; P91-F120 VanDerWaalsContact CB-CD1 3.45Å; P91-F120 HydrophobicContact CB-CD2 4.31Å; P91-F120 HydrophobicContact CB-CE1 3.45Å; P91-F120 VanDerWaalsContact CB-CE1 3.45Å; P91-F120 HydrophobicContact CB-CE2 4.3Å; P91-F120 HydrophobicContact CB-CG 3.91Å; P91-F120 HydrophobicContact CB-CZ 3.89Å; P91-F120 HydrophobicContact CG-CD1 3.9Å; P91-F120 HydrophobicContact CG-CE1 3.31Å; P91-F120 HydrophobicContact CG-CE2 4.28Å; P91-F120 HydrophobicContact CG-CZ 3.53Å
92	F	94.8	Very high	92.2	Very high	56 Å²	56	34.8 Å²	34.8	25%	0.246	17%	0.171	C	C	.	.	H	α-helix	trans	-63.2	-47.8	175.5	177.7	-97.4	0	0	0	111.3	F88 M89 V90 G95 Y96 L110 W117	F88-F92 VanDerWaalsContact O-CB 3.23Å; F88-F92 WeakPolarHBondContact O-CB 3.41Å; F88-F92 PolarHBondContact O-N 2.86Å; M89-F92 WeakPolarHBondContact O-CB 3.27Å; M89-F92 PolarHBondContact O-N 3.37Å; V90-F92 VanDerWaalsContact C-N 3.29Å; V90-F92 PolarHBondContact O-N 3.25Å; F92-G95 PolarHBondContact O-N 2.97Å; F92-Y96 WeakPolarHBondContact O-CB 3.44Å; F92-Y96 PolarHBondContact O-N 3.24Å; F92-L110 HydrophobicContact CZ-CD1 4.09Å; F92-W117 HydrophobicContact CB-CG 4.23Å; F92-W117 HydrophobicContact CD2-CB 4.2Å; F92-W117 HydrophobicContact CD2-CG 4.09Å
93	Y	93.9	Very high	91.5	Very high	73 Å²	73	46.2 Å²	46.2	29%	0.286	21%	0.214	S	C	.	.	H	α-helix	trans	-67	-36.3	178.1	-78.5	-72.2	0	0	0	112.3	V39 I43 M89 V90 G95 Y96 F97	V39-Y93 HydrophobicContact CG1-CD1 4.11Å; V39-Y93 HydrophobicContact CG1-CE1 3.61Å; V39-Y93 HydrophobicContact CG1-CE2 4.39Å; I43-Y93 HydrophobicContact CD1-CD1 4.31Å; I43-Y93 HydrophobicContact CD1-CD2 3.23Å; I43-Y93 HydrophobicContact CD1-CE2 3.56Å; I43-Y93 HydrophobicContact CD1-CG 3.65Å; M89-Y93 WeakPolarHBondContact O-CD2 3.32Å; M89-Y93 PolarHBondContact O-N 2.9Å; V90-Y93 PolarHBondContact O-N 2.98Å; Y93-G95 PolarHBondContact O-N 3.43Å; Y93-Y96 PolarHBondContact O-N 2.88Å; Y93-F97 HydrophobicContact CD1-CE2 4.2Å; Y93-F97 WeakPolarHBondContact O-CD2 3.48Å; Y93-F97 PolarHBondContact O-N 2.77Å
94	I	93.1	Very high	90.8	Very high	19 Å²	19	53.9 Å²	53.9	10%	0.097	25%	0.254	C	S	.	.	H	α-helix	trans	-56.5	-52.1	171.8	-70.7	165.8	0	0	0	109.8	V90 P91 Y96 F97 I98 V378 L381 L382 Q385	V90-I94 HydrophobicContact CG1-CD1 3.72Å; V90-I94 HydrophobicContact CG1-CG1 4.28Å; V90-I94 VanDerWaalsContact O-CG1 3.31Å; V90-I94 WeakPolarHBondContact O-CG1 3.33Å; V90-I94 PolarHBondContact O-N 3.21Å; P91-I94 PolarHBondContact O-N 3.02Å; I94-Y96 VanDerWaalsContact C-N 3.33Å; I94-Y96 PolarHBondContact O-N 3.38Å; I94-F97 PolarHBondContact O-N 2.71Å; I94-I98 HydrophobicContact CG2-CD1 3.62Å; I94-I98 HydrophobicContact CG2-CG1 4.42Å; I94-I98 WeakPolarHBondContact O-CB 3.36Å; I94-I98 VanDerWaalsContact O-CG1 3.23Å; I94-I98 WeakPolarHBondContact O-CG1 3.46Å; I94-I98 PolarHBondContact O-N 3.42Å; I94-V378 HydrophobicContact CG2-CG1 4.41Å; I94-L381 HydrophobicContact CD1-CB 4.26Å; I94-L381 HydrophobicContact CG1-CB 3.53Å; I94-L381 HydrophobicContact CG1-CD1 4.3Å; I94-L382 HydrophobicContact CD1-CD2 3.89Å; I94-L382 HydrophobicContact CD1-CG 4.36Å; I94-L382 HydrophobicContact CG2-CD2 4.44Å; I94-Q385 HydrophobicContact CD1-CB 4.41Å
95	G	92.4	Very high	90.1	Very high	0 Å²	0	51.7 Å²	51.7	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-57.9	-44.7	176.7	0	0	0	0	0	112.7	P91 F92 Y93 F97 I98 V99	P91-G95 PolarHBondContact O-N 3.22Å; F92-G95 PolarHBondContact O-N 2.97Å; Y93-G95 PolarHBondContact O-N 3.43Å; G95-F97 PolarHBondContact O-N 2.69Å; G95-I98 PolarHBondContact O-N 3.19Å; G95-V99 VanDerWaalsContact O-CG2 3.32Å; G95-V99 WeakPolarHBondContact O-CG2 3.49Å; G95-V99 PolarHBondContact O-N 3.49Å
96	Y	92.4	Very high	89.2	Confident	50 Å²	50	56.9 Å²	56.9	20%	0.196	27%	0.267	C	S	.	.	H	α-helix	trans	-58.7	-46.3	177.6	-178.7	-95.4	0	0	0	113.4	F92 Y93 I94 S100 R109 S113	F92-Y96 WeakPolarHBondContact O-CB 3.44Å; F92-Y96 PolarHBondContact O-N 3.24Å; Y93-Y96 PolarHBondContact O-N 2.88Å; I94-Y96 VanDerWaalsContact C-N 3.33Å; I94-Y96 PolarHBondContact O-N 3.38Å; Y96-S100 VanDerWaalsContact O-CB 3.29Å; Y96-S100 WeakPolarHBondContact O-CB 3.45Å; Y96-S100 PolarHBondContact O-N 2.88Å; Y96-R109 HydrophobicContact CD2-CG 4.13Å; Y96-R109 HydrophobicContact CE2-CG 4.01Å; Y96-R109 VanDerWaalsContact CZ-NE 3.28Å; Y96-R109 PolarHBondContact OH-NE 3.29Å; Y96-R109 PolarHBondContact OH-NH2 3.02Å; Y96-S113 VanDerWaalsContact CA-OG 3.27Å; Y96-S113 WeakPolarHBondContact CA-OG 3.48Å
97	F	90.4	Very high	88.5	Confident	3 Å²	3	66.9 Å²	66.9	1%	0.013	31%	0.31	C	S	.	.	H	α-helix	trans	-71.9	-36.1	179.2	-76.9	-64.8	0	0	0	112.9	Q37 V40 Y93 I94 G95 S100 N101 N377 V378 L381	Q37-F97 HydrophobicContact CB-CE1 4.47Å; Q37-F97 HydrophobicContact CB-CZ 4.23Å; Q37-F97 HydrophobicContact CG-CE1 4.08Å; Q37-F97 HydrophobicContact CG-CZ 4.31Å; V40-F97 HydrophobicContact CG2-CD2 4.26Å; V40-F97 HydrophobicContact CG2-CE2 3.47Å; V40-F97 VanDerWaalsContact CG2-CE2 3.47Å; V40-F97 HydrophobicContact CG2-CZ 3.63Å; Y93-F97 HydrophobicContact CD1-CE2 4.2Å; Y93-F97 WeakPolarHBondContact O-CD2 3.48Å; Y93-F97 PolarHBondContact O-N 2.77Å; I94-F97 PolarHBondContact O-N 2.71Å; G95-F97 PolarHBondContact O-N 2.69Å; F97-S100 WeakPolarHBondContact CA-OG 3.29Å; F97-S100 PolarHBondContact O-N 3.35Å; F97-S100 PolarHBondContact O-OG 2.97Å; F97-N101 PolarHBondContact O-N 3.12Å; F97-N101 PolarHBondContact O-ND2 2.94Å; F97-N377 HydrophobicContact CD1-CB 4.15Å; F97-N377 HydrophobicContact CE1-CB 4.45Å; F97-N377 HydrophobicContact CG-CB 4.22Å; F97-V378 HydrophobicContact CB-CG2 3.62Å; F97-L381 HydrophobicContact CD2-CD1 3.37Å; F97-L381 HydrophobicContact CE2-CD1 3.78Å; F97-L381 HydrophobicContact CG-CD1 4.47Å
98	I	89.8	Confident	88.2	Confident	64 Å²	64	72 Å²	72	33%	0.328	33%	0.334	S	S	.	.	H	α-helix	trans	-58.9	-50.8	173.3	-70.6	168.4	0	0	0	110.2	I94 G95 S100 N101 L116 V378	I94-I98 HydrophobicContact CG2-CD1 3.62Å; I94-I98 HydrophobicContact CG2-CG1 4.42Å; I94-I98 WeakPolarHBondContact O-CB 3.36Å; I94-I98 VanDerWaalsContact O-CG1 3.23Å; I94-I98 WeakPolarHBondContact O-CG1 3.46Å; I94-I98 PolarHBondContact O-N 3.42Å; G95-I98 PolarHBondContact O-N 3.19Å; I98-S100 VanDerWaalsContact C-N 3.31Å; I98-S100 PolarHBondContact O-N 2.83Å; I98-N101 PolarHBondContact O-N 3.46Å; I98-L116 HydrophobicContact CG2-CD1 4.27Å; I98-V378 HydrophobicContact CD1-CG1 4.28Å; I98-V378 HydrophobicContact CG1-CG1 3.9Å; I98-V378 HydrophobicContact CG1-CG2 4.02Å
99	V	90.6	Very high	87.9	Confident	6 Å²	6	72.7 Å²	72.7	4%	0.036	34%	0.335	C	S	.	.	H	α-helix	trans	-65.7	-36.6	179.3	177.6	0	0	0	0	111	G95 N101 I102 L105 R109 F112	G95-V99 VanDerWaalsContact O-CG2 3.32Å; G95-V99 WeakPolarHBondContact O-CG2 3.49Å; G95-V99 PolarHBondContact O-N 3.49Å; V99-N101 PolarHBondContact O-N 3.33Å; V99-I102 PolarHBondContact O-N 3.03Å; V99-L105 HydrophobicContact CG1-CB 3.83Å; V99-L105 HydrophobicContact CG1-CD1 4.1Å; V99-R109 HydrophobicContact CB-CG 4.36Å; V99-R109 HydrophobicContact CG1-CB 4.23Å; V99-R109 HydrophobicContact CG1-CG 3.94Å; V99-F112 HydrophobicContact CG1-CB 3.81Å; V99-F112 HydrophobicContact CG2-CB 3.91Å
100	S	86	Confident	87.7	Confident	33 Å²	33	73.4 Å²	73.4	23%	0.231	34%	0.34	C	S	.	.	H	α-helix	trans	-62	-27.2	177.9	80.2	0	0	0	0	113.8	Y96 F97 I98 I102	Y96-S100 VanDerWaalsContact O-CB 3.29Å; Y96-S100 WeakPolarHBondContact O-CB 3.45Å; Y96-S100 PolarHBondContact O-N 2.88Å; F97-S100 WeakPolarHBondContact CA-OG 3.29Å; F97-S100 PolarHBondContact O-N 3.35Å; F97-S100 PolarHBondContact O-OG 2.97Å; I98-S100 VanDerWaalsContact C-N 3.31Å; I98-S100 PolarHBondContact O-N 2.83Å; S100-I102 VanDerWaalsContact C-N 3.27Å; S100-I102 PolarHBondContact O-N 3.31Å
101	N	84.2	Confident	87.5	Confident	89 Å²	89	78.2 Å²	78.2	48%	0.476	37%	0.365	S	S	.	.	T	Hydrogen-bonded Turn	trans	-76.1	-16.3	176.7	-76	-26.5	0	0	0	112.8	F97 I98 V99 K374	F97-N101 PolarHBondContact O-N 3.12Å; F97-N101 PolarHBondContact O-ND2 2.94Å; I98-N101 PolarHBondContact O-N 3.46Å; V99-N101 PolarHBondContact O-N 3.33Å; N101-K374 PolarHBondContact ND2-O 3.31Å; N101-K374 PolarHBondContact OD1-O 3.05Å
102	I	85.4	Confident	87.3	Confident	78 Å²	78	81.3 Å²	81.3	40%	0.4	38%	0.379	S	S	.	.			trans	-92.8	104.3	179.7	-56.2	171.3	0	0	0	108.9	V99 S100 L104 L105	V99-I102 PolarHBondContact O-N 3.03Å; S100-I102 VanDerWaalsContact C-N 3.27Å; S100-I102 PolarHBondContact O-N 3.31Å; I102-L104 HydrophobicContact CG2-CB 4.23Å; I102-L104 PolarHBondContact O-N 3.26Å; I102-L104 VanDerWaalsContact O-N 3.1Å; I102-L105 HydrophobicContact CB-CD1 4.33Å; I102-L105 HydrophobicContact CB-CG 4.38Å; I102-L105 HydrophobicContact CD1-CD1 4.12Å; I102-L105 HydrophobicContact CG2-CB 4.45Å; I102-L105 HydrophobicContact CG2-CD1 4.12Å; I102-L105 HydrophobicContact CG2-CG 3.91Å; I102-L105 PolarHBondContact O-N 2.85Å
103	R	80.2	Confident	87.2	Confident	239 Å²	239	78.7 Å²	78.7	90%	0.902	37%	0.367	S	S	*	.	G	3₁₀ helix	trans	-53.4	-35.4	-177.7	-68.5	-177	179.2	-178	-1.6	113.5	L105 H106	R103-L105 VanDerWaalsContact C-N 3.27Å; R103-L105 PolarHBondContact O-N 2.75Å; R103-H106 PolarHBondContact O-N 3.15Å
104	L	79.3	Confident	87.2	Confident	164 Å²	164	77.6 Å²	77.6	86%	0.859	37%	0.37	S	S	*	.	G	3₁₀ helix	trans	-65.4	-28.4	-177.4	-151	87.5	0	0	0	113.1	I102	I102-L104 HydrophobicContact CG2-CB 4.23Å; I102-L104 PolarHBondContact O-N 3.26Å; I102-L104 VanDerWaalsContact O-N 3.1Å
105	L	79.6	Confident	87.2	Confident	36 Å²	36	80.7 Å²	80.7	19%	0.188	39%	0.386	C	S	.	.	G	3₁₀ helix	trans	-99	8.1	-172.5	-58.6	-177.8	0	0	0	113.1	V99 I102 R103 K107 Q108 R109 F112	V99-L105 HydrophobicContact CG1-CB 3.83Å; V99-L105 HydrophobicContact CG1-CD1 4.1Å; I102-L105 HydrophobicContact CB-CD1 4.33Å; I102-L105 HydrophobicContact CB-CG 4.38Å; I102-L105 HydrophobicContact CD1-CD1 4.12Å; I102-L105 HydrophobicContact CG2-CB 4.45Å; I102-L105 HydrophobicContact CG2-CD1 4.12Å; I102-L105 HydrophobicContact CG2-CG 3.91Å; I102-L105 PolarHBondContact O-N 2.85Å; R103-L105 VanDerWaalsContact C-N 3.27Å; R103-L105 PolarHBondContact O-N 2.75Å; L105-K107 VanDerWaalsContact C-N 3.3Å; L105-K107 PolarHBondContact O-N 2.88Å; L105-Q108 CarbonylContact O-C 3.4Å; L105-Q108 PolarHBondContact O-N 2.9Å; L105-Q108 VanDerWaalsContact O-N 3.08Å; L105-R109 WeakPolarHBondContact O-CA 3.47Å; L105-R109 PolarHBondContact O-N 3.3Å; L105-F112 HydrophobicContact CB-CD2 4.35Å; L105-F112 HydrophobicContact CD1-CB 4.42Å; L105-F112 HydrophobicContact CD1-CD1 4.25Å; L105-F112 HydrophobicContact CD1-CD2 4.25Å; L105-F112 HydrophobicContact CD1-CG 4.05Å; L105-F112 HydrophobicContact CD2-CD2 3.88Å; L105-F112 HydrophobicContact CD2-CE1 4.36Å; L105-F112 HydrophobicContact CD2-CE2 3.56Å; L105-F112 HydrophobicContact CD2-CG 4.41Å; L105-F112 HydrophobicContact CD2-CZ 3.82Å; L105-F112 HydrophobicContact CG-CD2 4.38Å
106	H	76.7	Confident	87.2	Confident	119 Å²	119	83.6 Å²	83.6	55%	0.551	40%	0.401	S	S	*	.	G	3₁₀ helix	trans	-57.3	-39.9	-171.9	-169.6	-87.6	0	0	0	113.2	R103	R103-H106 PolarHBondContact O-N 3.15Å
107	K	80.3	Confident	87.3	Confident	210 Å²	210	83.9 Å²	83.9	91%	0.913	40%	0.402	S	S	*	.	G	3₁₀ helix	trans	-70.2	-31.5	179.1	-72.3	-170.9	178.9	-176.9	0	113.6	L105	L105-K107 VanDerWaalsContact C-N 3.3Å; L105-K107 PolarHBondContact O-N 2.88Å
108	Q	86.3	Confident	87.5	Confident	110 Å²	110	88 Å²	88	51%	0.514	42%	0.424	S	S	.	.	G	3₁₀ helix	trans	-109.7	21.8	-177.3	-68.2	-178.1	-14.4	0	0	112.1	L105 L110 L111 F112	L105-Q108 CarbonylContact O-C 3.4Å; L105-Q108 PolarHBondContact O-N 2.9Å; L105-Q108 VanDerWaalsContact O-N 3.08Å; Q108-L110 VanDerWaalsContact C-N 3.3Å; Q108-L110 PolarHBondContact O-N 3.42Å; Q108-L111 WeakPolarHBondContact O-CB 3.39Å; Q108-L111 PolarHBondContact O-N 2.94Å; Q108-F112 HydrophobicContact CB-CD2 3.77Å; Q108-F112 HydrophobicContact CB-CE2 3.78Å; Q108-F112 WeakPolarHBondContact O-CD2 3.43Å; Q108-F112 PolarHBondContact O-N 3.5Å; Q108-F112 VanDerWaalsContact O-N 3.12Å; Q108-F112 VanDerWaalsContact OE1-CE2 3.3Å
109	R	87.2	Confident	87.7	Confident	70 Å²	70	88.5 Å²	88.5	26%	0.264	43%	0.43	S	S	.	.	H	α-helix	trans	-51.5	-48.6	-171.9	178.2	176.5	63.2	-155.4	-1.4	112	Y96 V99 L105 L111 F112 S113	Y96-R109 HydrophobicContact CD2-CG 4.13Å; Y96-R109 HydrophobicContact CE2-CG 4.01Å; Y96-R109 VanDerWaalsContact CZ-NE 3.28Å; Y96-R109 PolarHBondContact OH-NE 3.29Å; Y96-R109 PolarHBondContact OH-NH2 3.02Å; V99-R109 HydrophobicContact CB-CG 4.36Å; V99-R109 HydrophobicContact CG1-CB 4.23Å; V99-R109 HydrophobicContact CG1-CG 3.94Å; L105-R109 WeakPolarHBondContact O-CA 3.47Å; L105-R109 PolarHBondContact O-N 3.3Å; R109-L111 PolarHBondContact O-N 3.47Å; R109-F112 PolarHBondContact O-N 2.85Å; R109-S113 WeakPolarHBondContact O-CB 3.48Å; R109-S113 PolarHBondContact O-N 3.35Å; R109-S113 PolarHBondContact O-OG 3.09Å
110	L	88.9	Confident	87.8	Confident	117 Å²	117	91.2 Å²	91.2	61%	0.613	44%	0.441	S	S	*	.	H	α-helix	trans	-62.2	-41.8	-178	-171.3	71.1	0	0	0	112.2	F92 Q108 S113 C114	F92-L110 HydrophobicContact CZ-CD1 4.09Å; Q108-L110 VanDerWaalsContact C-N 3.3Å; Q108-L110 PolarHBondContact O-N 3.42Å; L110-S113 PolarHBondContact O-N 2.75Å; L110-C114 WeakPolarHBondContact O-CB 3.46Å; L110-C114 PolarHBondContact O-N 3.03Å
111	L	91.4	Very high	88	Confident	101 Å²	101	90.7 Å²	90.7	53%	0.529	44%	0.435	S	S	.	.	H	α-helix	trans	-63	-51.3	179.8	-176.3	71.9	0	0	0	110.9	Q108 R109 S113 C114 L115	Q108-L111 WeakPolarHBondContact O-CB 3.39Å; Q108-L111 PolarHBondContact O-N 2.94Å; R109-L111 PolarHBondContact O-N 3.47Å; L111-S113 VanDerWaalsContact C-N 3.28Å; L111-S113 PolarHBondContact O-N 3.41Å; L111-C114 WeakPolarHBondContact O-CB 3.37Å; L111-C114 PolarHBondContact O-N 3.49Å; L111-L115 WeakPolarHBondContact O-CG 3.43Å; L111-L115 PolarHBondContact O-N 3.26Å
112	F	91.6	Very high	88.4	Confident	71 Å²	71	93.5 Å²	93.5	31%	0.311	44%	0.44	S	S	.	.	H	α-helix	trans	-65.4	-32.5	177.8	-77.9	-79	0	0	0	112.6	V99 L105 Q108 R109 L115 L116	V99-F112 HydrophobicContact CG1-CB 3.81Å; V99-F112 HydrophobicContact CG2-CB 3.91Å; L105-F112 HydrophobicContact CB-CD2 4.35Å; L105-F112 HydrophobicContact CD1-CB 4.42Å; L105-F112 HydrophobicContact CD1-CD1 4.25Å; L105-F112 HydrophobicContact CD1-CD2 4.25Å; L105-F112 HydrophobicContact CD1-CG 4.05Å; L105-F112 HydrophobicContact CD2-CD2 3.88Å; L105-F112 HydrophobicContact CD2-CE1 4.36Å; L105-F112 HydrophobicContact CD2-CE2 3.56Å; L105-F112 HydrophobicContact CD2-CG 4.41Å; L105-F112 HydrophobicContact CD2-CZ 3.82Å; L105-F112 HydrophobicContact CG-CD2 4.38Å; Q108-F112 HydrophobicContact CB-CD2 3.77Å; Q108-F112 HydrophobicContact CB-CE2 3.78Å; Q108-F112 WeakPolarHBondContact O-CD2 3.43Å; Q108-F112 PolarHBondContact O-N 3.5Å; Q108-F112 VanDerWaalsContact O-N 3.12Å; Q108-F112 VanDerWaalsContact OE1-CE2 3.3Å; R109-F112 PolarHBondContact O-N 2.85Å; F112-L115 HydrophobicContact CD1-CD1 4.33Å; F112-L115 PolarHBondContact O-N 3.02Å; F112-L116 WeakPolarHBondContact O-CB 3.35Å; F112-L116 PolarHBondContact O-N 3.01Å
113	S	91.7	Very high	88.7	Confident	0 Å²	0	96 Å²	96	0%	0	45%	0.449	C	S	.	.	H	α-helix	trans	-66	-42.2	174.3	-52.3	0	0	0	0	111.2	Y96 R109 L110 L111 L116 W117	Y96-S113 VanDerWaalsContact CA-OG 3.27Å; Y96-S113 WeakPolarHBondContact CA-OG 3.48Å; R109-S113 WeakPolarHBondContact O-CB 3.48Å; R109-S113 PolarHBondContact O-N 3.35Å; R109-S113 PolarHBondContact O-OG 3.09Å; L110-S113 PolarHBondContact O-N 2.75Å; L111-S113 VanDerWaalsContact C-N 3.28Å; L111-S113 PolarHBondContact O-N 3.41Å; S113-L116 PolarHBondContact O-N 3Å; S113-W117 VanDerWaalsContact O-CB 3.27Å; S113-W117 WeakPolarHBondContact O-CB 3.33Å; S113-W117 PolarHBondContact O-N 3.29Å
114	C	93.2	Very high	89.2	Confident	50 Å²	50	85.1 Å²	85.1	34%	0.338	41%	0.408	S	S	.	.	H	α-helix	trans	-64.4	-42	175	-170.9	0	0	0	0	111.3	L110 L111 W117 L118	L110-C114 WeakPolarHBondContact O-CB 3.46Å; L110-C114 PolarHBondContact O-N 3.03Å; L111-C114 WeakPolarHBondContact O-CB 3.37Å; L111-C114 PolarHBondContact O-N 3.49Å; C114-W117 PolarHBondContact O-N 2.96Å; C114-L118 WeakPolarHBondContact O-CB 3.48Å; C114-L118 VanDerWaalsContact O-CG 3.32Å; C114-L118 WeakPolarHBondContact O-CG 3.38Å; C114-L118 PolarHBondContact O-N 3.42Å
115	L	94	Very high	89.5	Confident	84 Å²	84	79.9 Å²	79.9	44%	0.44	38%	0.377	S	S	.	.	H	α-helix	trans	-60.7	-48.3	174.4	-71.9	172.6	0	0	0	111.9	L111 F112 W117 L118 T119	L111-L115 WeakPolarHBondContact O-CG 3.43Å; L111-L115 PolarHBondContact O-N 3.26Å; F112-L115 HydrophobicContact CD1-CD1 4.33Å; F112-L115 PolarHBondContact O-N 3.02Å; L115-W117 VanDerWaalsContact C-N 3.28Å; L115-W117 PolarHBondContact O-N 2.89Å; L115-L118 PolarHBondContact O-N 2.96Å; L115-T119 PolarHBondContact O-N 3.41Å; L115-T119 PolarHBondContact O-OG1 3Å
116	L	92.8	Very high	89.9	Confident	62 Å²	62	83.3 Å²	83.3	33%	0.325	39%	0.39	S	S	.	.	H	α-helix	trans	-61.3	-40.6	178	-165.1	158	0	0	0	111	I98 F112 S113 T119 F120	I98-L116 HydrophobicContact CG2-CD1 4.27Å; F112-L116 WeakPolarHBondContact O-CB 3.35Å; F112-L116 PolarHBondContact O-N 3.01Å; S113-L116 PolarHBondContact O-N 3Å; L116-T119 WeakPolarHBondContact O-CB 3.38Å; L116-T119 PolarHBondContact O-N 3.13Å; L116-F120 PolarHBondContact O-N 3.21Å
117	W	94.4	Very high	90.3	Very high	55 Å²	55	81.7 Å²	81.7	21%	0.208	39%	0.385	C	S	.	.	H	α-helix	trans	-64.3	-43.8	174.3	178.8	81.4	0	0	0	112.8	F88 F92 S113 C114 L115 T119 F120 M121	F88-W117 HydrophobicContact CD1-CH2 4.46Å; F88-W117 AromaticContact CD1-CZ2 3.78Å; F88-W117 HydrophobicContact CD1-CZ2 3.78Å; F88-W117 PolarHBondContact O-NE1 3.4Å; F88-W117 VanDerWaalsContact O-NE1 3.16Å; F92-W117 HydrophobicContact CB-CG 4.23Å; F92-W117 HydrophobicContact CD2-CB 4.2Å; F92-W117 HydrophobicContact CD2-CG 4.09Å; S113-W117 VanDerWaalsContact O-CB 3.27Å; S113-W117 WeakPolarHBondContact O-CB 3.33Å; S113-W117 PolarHBondContact O-N 3.29Å; C114-W117 PolarHBondContact O-N 2.96Å; L115-W117 VanDerWaalsContact C-N 3.28Å; L115-W117 PolarHBondContact O-N 2.89Å; W117-T119 VanDerWaalsContact C-N 3.31Å; W117-T119 PolarHBondContact O-N 3.32Å; W117-F120 WeakPolarHBondContact O-CB 3.5Å; W117-F120 PolarHBondContact O-N 3.46Å; W117-M121 HydrophobicContact CD2-CG 4.02Å; W117-M121 HydrophobicContact CE3-CG 4.31Å; W117-M121 HydrophobicContact CH2-CE 4.47Å; W117-M121 HydrophobicContact CH2-CG 4.47Å; W117-M121 HydrophobicContact CZ2-CE 4.28Å; W117-M121 HydrophobicContact CZ2-CG 4.22Å; W117-M121 HydrophobicContact CZ2-SD 4.41Å; W117-M121 HydrophobicContact CZ3-CG 4.49Å; W117-M121 VanDerWaalsContact O-CG 3.22Å; W117-M121 WeakPolarHBondContact O-CG 3.25Å; W117-M121 PolarHBondContact O-N 3.45Å
118	L	94	Very high	90.2	Very high	90 Å²	90	71.8 Å²	71.8	47%	0.471	34%	0.342	S	S	.	.	H	α-helix	trans	-62.5	-39.3	174.4	-74.4	173.3	0	0	0	111.6	C114 L115 M121 Y122	C114-L118 WeakPolarHBondContact O-CB 3.48Å; C114-L118 VanDerWaalsContact O-CG 3.32Å; C114-L118 WeakPolarHBondContact O-CG 3.38Å; C114-L118 PolarHBondContact O-N 3.42Å; L115-L118 PolarHBondContact O-N 2.96Å; L118-M121 PolarHBondContact O-N 3.44Å; L118-Y122 WeakPolarHBondContact O-CB 3.42Å; L118-Y122 PolarHBondContact O-N 3.47Å
119	T	93.6	Very high	89.8	Confident	74 Å²	74	70.2 Å²	70.2	45%	0.454	34%	0.337	S	S	.	.	H	α-helix	trans	-62.5	-45.8	173.1	-58.7	0	0	0	0	111.2	L115 L116 W117 M121 Y122 F123	L115-T119 PolarHBondContact O-N 3.41Å; L115-T119 PolarHBondContact O-OG1 3Å; L116-T119 WeakPolarHBondContact O-CB 3.38Å; L116-T119 PolarHBondContact O-N 3.13Å; W117-T119 VanDerWaalsContact C-N 3.31Å; W117-T119 PolarHBondContact O-N 3.32Å; T119-M121 PolarHBondContact O-N 3.04Å; T119-Y122 PolarHBondContact O-N 3.35Å; T119-F123 HydrophobicContact CG2-CD2 3.67Å; T119-F123 HydrophobicContact CG2-CE2 3.45Å; T119-F123 VanDerWaalsContact CG2-CE2 3.45Å; T119-F123 WeakPolarHBondContact O-CD2 3.48Å; T119-F123 PolarHBondContact O-N 3.3Å
120	F	92.8	Very high	89.2	Confident	64 Å²	64	71.8 Å²	71.8	28%	0.281	36%	0.357	S	S	.	.	H	α-helix	trans	-58.2	-47.6	174	171.1	-91.2	0	0	0	111.3	P91 L116 W117 Y122 F123 F124	P91-F120 HydrophobicContact CB-CD1 3.45Å; P91-F120 VanDerWaalsContact CB-CD1 3.45Å; P91-F120 HydrophobicContact CB-CD2 4.31Å; P91-F120 HydrophobicContact CB-CE1 3.45Å; P91-F120 VanDerWaalsContact CB-CE1 3.45Å; P91-F120 HydrophobicContact CB-CE2 4.3Å; P91-F120 HydrophobicContact CB-CG 3.91Å; P91-F120 HydrophobicContact CB-CZ 3.89Å; P91-F120 HydrophobicContact CG-CD1 3.9Å; P91-F120 HydrophobicContact CG-CE1 3.31Å; P91-F120 HydrophobicContact CG-CE2 4.28Å; P91-F120 HydrophobicContact CG-CZ 3.53Å; L116-F120 PolarHBondContact O-N 3.21Å; W117-F120 WeakPolarHBondContact O-CB 3.5Å; W117-F120 PolarHBondContact O-N 3.46Å; F120-Y122 VanDerWaalsContact C-N 3.34Å; F120-Y122 PolarHBondContact O-N 2.57Å; F120-F123 PolarHBondContact O-N 2.91Å; F120-F124 HydrophobicContact CE1-CB 4.17Å; F120-F124 HydrophobicContact CE1-CG 4.4Å; F120-F124 HydrophobicContact CZ-CB 4.34Å; F120-F124 HydrophobicContact CZ-CD2 4.22Å; F120-F124 HydrophobicContact CZ-CG 4.49Å; F120-F124 WeakPolarHBondContact O-CB 3.44Å; F120-F124 PolarHBondContact O-N 2.99Å
121	M	91.4	Very high	88.4	Confident	21 Å²	21	67.6 Å²	67.6	10%	0.103	33%	0.333	C	S	.	.	H	α-helix	trans	-60.4	-43.9	178	-68.4	-69.9	-81	0	0	110.9	V87 F88 W117 L118 T119 F123 F124 W125	V87-M121 HydrophobicContact CG1-CE 4.33Å; V87-M121 HydrophobicContact CG1-SD 3.96Å; F88-M121 HydrophobicContact CD1-CE 3.75Å; F88-M121 HydrophobicContact CD1-SD 4.49Å; F88-M121 HydrophobicContact CE1-CE 3.34Å; F88-M121 HydrophobicContact CZ-CE 4.07Å; W117-M121 HydrophobicContact CD2-CG 4.02Å; W117-M121 HydrophobicContact CE3-CG 4.31Å; W117-M121 HydrophobicContact CH2-CE 4.47Å; W117-M121 HydrophobicContact CH2-CG 4.47Å; W117-M121 HydrophobicContact CZ2-CE 4.28Å; W117-M121 HydrophobicContact CZ2-CG 4.22Å; W117-M121 HydrophobicContact CZ2-SD 4.41Å; W117-M121 HydrophobicContact CZ3-CG 4.49Å; W117-M121 VanDerWaalsContact O-CG 3.22Å; W117-M121 WeakPolarHBondContact O-CG 3.25Å; W117-M121 PolarHBondContact O-N 3.45Å; L118-M121 PolarHBondContact O-N 3.44Å; T119-M121 PolarHBondContact O-N 3.04Å; M121-F123 PolarHBondContact O-N 3.19Å; M121-F124 PolarHBondContact O-N 2.9Å; M121-W125 HydrophobicContact CB-CE3 4.43Å; M121-W125 HydrophobicContact CB-CZ3 4.4Å; M121-W125 HydrophobicContact CE-CE3 4.2Å; M121-W125 HydrophobicContact CE-CH2 3.48Å; M121-W125 VanDerWaalsContact CE-CH2 3.48Å; M121-W125 HydrophobicContact CE-CZ3 3.13Å; M121-W125 PolarHBondContact O-N 2.76Å; M121-W125 HydrophobicContact SD-CE3 4.46Å; M121-W125 HydrophobicContact SD-CH2 4.5Å; M121-W125 HydrophobicContact SD-CZ3 3.65Å
122	Y	91.8	Very high	87.3	Confident	148 Å²	148	65.9 Å²	65.9	58%	0.58	33%	0.329	S	S	*	.	H	α-helix	trans	-57.5	-50.9	175	175.3	-94.7	0	0	0	112.1	L118 T119 F120 W125 K126	L118-Y122 WeakPolarHBondContact O-CB 3.42Å; L118-Y122 PolarHBondContact O-N 3.47Å; T119-Y122 PolarHBondContact O-N 3.35Å; F120-Y122 VanDerWaalsContact C-N 3.34Å; F120-Y122 PolarHBondContact O-N 2.57Å; Y122-W125 PolarHBondContact O-N 3.44Å; Y122-K126 WeakPolarHBondContact O-CB 3.26Å; Y122-K126 PolarHBondContact O-N 3.36Å
123	F	91.3	Very high	86	Confident	132 Å²	132	63.5 Å²	63.5	58%	0.579	32%	0.319	S	S	*	.	H	α-helix	trans	-65.4	-39.7	178.2	-77.6	-64	0	0	0	112.5	T119 F120 M121 W125 K126 L127	T119-F123 HydrophobicContact CG2-CD2 3.67Å; T119-F123 HydrophobicContact CG2-CE2 3.45Å; T119-F123 VanDerWaalsContact CG2-CE2 3.45Å; T119-F123 WeakPolarHBondContact O-CD2 3.48Å; T119-F123 PolarHBondContact O-N 3.3Å; F120-F123 PolarHBondContact O-N 2.91Å; M121-F123 PolarHBondContact O-N 3.19Å; F123-W125 VanDerWaalsContact C-N 3.29Å; F123-W125 PolarHBondContact O-N 2.8Å; F123-K126 PolarHBondContact O-N 3.35Å; F123-L127 VanDerWaalsContact O-CB 3.29Å; F123-L127 WeakPolarHBondContact O-CB 3.47Å; F123-L127 PolarHBondContact O-N 3.12Å
124	F	90.5	Very high	84.3	Confident	9 Å²	9	68.2 Å²	68.2	4%	0.039	34%	0.344	C	S	.	.	H	α-helix	trans	-62.1	-38.6	176.9	178.9	-95.3	0	0	0	111.5	V87 F120 M121 L146 R149 V150 I153	V87-F124 HydrophobicContact CG1-CD1 4.41Å; V87-F124 HydrophobicContact CG1-CE1 4.14Å; V87-F124 HydrophobicContact CG2-CE1 4.23Å; V87-F124 HydrophobicContact CG2-CZ 3.95Å; F120-F124 HydrophobicContact CE1-CB 4.17Å; F120-F124 HydrophobicContact CE1-CG 4.4Å; F120-F124 HydrophobicContact CZ-CB 4.34Å; F120-F124 HydrophobicContact CZ-CD2 4.22Å; F120-F124 HydrophobicContact CZ-CG 4.49Å; F120-F124 WeakPolarHBondContact O-CB 3.44Å; F120-F124 PolarHBondContact O-N 2.99Å; M121-F124 PolarHBondContact O-N 2.9Å; F124-L146 HydrophobicContact CE1-CD1 3.51Å; F124-L146 HydrophobicContact CZ-CD1 3.83Å; F124-R149 HydrophobicContact CE1-CB 4.14Å; F124-R149 HydrophobicContact CE2-CB 4.08Å; F124-R149 HydrophobicContact CZ-CB 3.6Å; F124-V150 HydrophobicContact CE2-CG2 4.24Å; F124-V150 HydrophobicContact CZ-CG2 3.97Å; F124-I153 HydrophobicContact CD2-CD1 3.99Å; F124-I153 HydrophobicContact CE2-CD1 3.87Å
125	W	87.2	Confident	82.8	Confident	54 Å²	54	67.2 Å²	67.2	21%	0.205	34%	0.337	C	S	.	.	H	α-helix	trans	-67.9	-47.6	172.5	-101.4	-103.4	0	0	0	112.1	V87 M121 Y122 F123 L127 G128 L141 R149	V87-W125 HydrophobicContact CG1-CZ3 4.43Å; M121-W125 HydrophobicContact CB-CE3 4.43Å; M121-W125 HydrophobicContact CB-CZ3 4.4Å; M121-W125 HydrophobicContact CE-CE3 4.2Å; M121-W125 HydrophobicContact CE-CH2 3.48Å; M121-W125 VanDerWaalsContact CE-CH2 3.48Å; M121-W125 HydrophobicContact CE-CZ3 3.13Å; M121-W125 PolarHBondContact O-N 2.76Å; M121-W125 HydrophobicContact SD-CE3 4.46Å; M121-W125 HydrophobicContact SD-CH2 4.5Å; M121-W125 HydrophobicContact SD-CZ3 3.65Å; Y122-W125 PolarHBondContact O-N 3.44Å; F123-W125 VanDerWaalsContact C-N 3.29Å; F123-W125 PolarHBondContact O-N 2.8Å; W125-L127 VanDerWaalsContact C-N 3.27Å; W125-L127 PolarHBondContact O-N 3.15Å; W125-G128 PolarHBondContact O-N 2.92Å; W125-G128 VanDerWaalsContact O-N 3.09Å; W125-L141 HydrophobicContact CH2-CD2 4.05Å; W125-L141 HydrophobicContact CZ2-CD2 3.66Å; W125-R149 VanDerWaalsContact CD2-NH1 3.27Å; W125-R149 VanDerWaalsContact NE1-NH1 3.13Å; W125-R149 PolarHBondContact O-NH2 2.97Å
126	K	86.9	Confident	81.1	Confident	109 Å²	109	69.3 Å²	69.3	47%	0.474	36%	0.356	S	S	.	.	H	α-helix	trans	-63.6	-32.9	-178.7	-163	73.7	-160.5	156.1	0	112.8	Y122 F123 G128 D129 P130	Y122-K126 WeakPolarHBondContact O-CB 3.26Å; Y122-K126 PolarHBondContact O-N 3.36Å; F123-K126 PolarHBondContact O-N 3.35Å; K126-G128 PolarHBondContact O-N 3.1Å; K126-D129 VanDerWaalsContact CD-OD2 3.29Å; K126-D129 WeakPolarHBondContact CD-OD2 3.37Å; K126-D129 VanDerWaalsContact CE-OD2 3.25Å; K126-D129 WeakPolarHBondContact CE-OD2 3.26Å; K126-D129 IonicContact NZ-OD2 3.71Å; K126-D129 PolarHBondContact NZ-OD2 3.03Å; K126-D129 WeakPolarHBondContact O-CB 3.44Å; K126-D129 PolarHBondContact O-N 3.35Å; K126-P130 WeakPolarHBondContact O-CD 3.33Å
127	L	84.3	Confident	79.5	Confident	85 Å²	85	74.5 Å²	74.5	45%	0.445	38%	0.375	S	S	.	.	H	α-helix	trans	-61.5	-26.9	176.7	-167.8	75.7	0	0	0	111.9	F123 W125 P130 F131 I153	F123-L127 VanDerWaalsContact O-CB 3.29Å; F123-L127 WeakPolarHBondContact O-CB 3.47Å; F123-L127 PolarHBondContact O-N 3.12Å; W125-L127 VanDerWaalsContact C-N 3.27Å; W125-L127 PolarHBondContact O-N 3.15Å; L127-P130 WeakPolarHBondContact O-CD 3.3Å; L127-F131 WeakPolarHBondContact O-CD2 3.39Å; L127-F131 WeakPolarHBondContact O-CE2 3.32Å; L127-I153 HydrophobicContact CD2-CD1 3.76Å; L127-I153 HydrophobicContact CD2-CG1 3.61Å
128	G	78.1	Confident	78	Confident	1 Å²	1	75.2 Å²	75.2	1%	0.01	38%	0.381	C	S	.	.	T	Hydrogen-bonded Turn	trans	-77.5	-21.8	177.8	0	0	0	0	0	114.6	W125 K126 F131	W125-G128 PolarHBondContact O-N 2.92Å; W125-G128 VanDerWaalsContact O-N 3.09Å; K126-G128 PolarHBondContact O-N 3.1Å; G128-F131 PolarHBondContact O-N 2.89Å
129	D	78.6	Confident	76.5	Confident	78 Å²	78	73.4 Å²	73.4	42%	0.417	38%	0.384	S	S	.	.	T	Hydrogen-bonded Turn	trans	-63.2	-38.4	-173.4	-65.1	-9	0	0	0	114.7	K126 F131	K126-D129 VanDerWaalsContact CD-OD2 3.29Å; K126-D129 WeakPolarHBondContact CD-OD2 3.37Å; K126-D129 VanDerWaalsContact CE-OD2 3.25Å; K126-D129 WeakPolarHBondContact CE-OD2 3.26Å; K126-D129 IonicContact NZ-OD2 3.71Å; K126-D129 PolarHBondContact NZ-OD2 3.03Å; K126-D129 WeakPolarHBondContact O-CB 3.44Å; K126-D129 PolarHBondContact O-N 3.35Å; D129-F131 PolarHBondContact O-N 2.67Å
130	P	75	Confident	75.2	Confident	103 Å²	103	75.7 Å²	75.7	67%	0.669	39%	0.392	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.3	-14.1	-179.9	-19.3	33.7	0	0	0	113.9	K126 L127	K126-P130 WeakPolarHBondContact O-CD 3.33Å; L127-P130 WeakPolarHBondContact O-CD 3.3Å
131	F	72.6	Confident	74	Confident	28 Å²	28	79.1 Å²	79.1	12%	0.123	41%	0.413	C	S	.	.	S	Bend	trans	-100.4	143.5	-171.8	-60.5	-63.7	0	0	0	110.7	L127 G128 D129 I133 V152 F421 W425	L127-F131 WeakPolarHBondContact O-CD2 3.39Å; L127-F131 WeakPolarHBondContact O-CE2 3.32Å; G128-F131 PolarHBondContact O-N 2.89Å; D129-F131 PolarHBondContact O-N 2.67Å; F131-I133 HydrophobicContact CB-CD1 3.38Å; F131-I133 HydrophobicContact CB-CG1 3.56Å; F131-I133 HydrophobicContact CD2-CD1 4.18Å; F131-I133 HydrophobicContact CG-CD1 4.13Å; F131-I133 PolarHBondContact O-N 3.25Å; F131-V152 HydrophobicContact CD2-CG1 4.17Å; F131-V152 HydrophobicContact CD2-CG2 4.18Å; F131-V152 HydrophobicContact CE1-CG1 4.29Å; F131-V152 HydrophobicContact CE2-CG1 3.6Å; F131-V152 HydrophobicContact CE2-CG2 4.43Å; F131-V152 HydrophobicContact CG-CG2 4.36Å; F131-V152 HydrophobicContact CZ-CG1 3.65Å; F131-F421 HydrophobicContact CB-CZ 4.14Å; F131-F421 HydrophobicContact CD1-CE1 4.15Å; F131-F421 AromaticContact CD1-CE2 3.71Å; F131-F421 HydrophobicContact CD1-CE2 3.71Å; F131-F421 AromaticContact CD1-CZ 3.18Å; F131-F421 HydrophobicContact CD1-CZ 3.18Å; F131-F421 HydrophobicContact CE1-CE2 4.38Å; F131-F421 AromaticContact CE1-CZ 3.76Å; F131-F421 HydrophobicContact CE1-CZ 3.76Å; F131-F421 AromaticContact CG-CZ 3.91Å; F131-F421 HydrophobicContact CG-CZ 3.91Å; F131-W425 HydrophobicContact CE1-CD2 4.27Å; F131-W425 HydrophobicContact CE1-CE3 4.09Å; F131-W425 AromaticContact CE1-CH2 3.75Å; F131-W425 HydrophobicContact CE1-CH2 3.75Å; F131-W425 AromaticContact CE1-CZ2 3.92Å; F131-W425 HydrophobicContact CE1-CZ2 3.92Å; F131-W425 AromaticContact CE1-CZ3 3.84Å; F131-W425 HydrophobicContact CE1-CZ3 3.84Å; F131-W425 AromaticContact CZ-CH2 4Å; F131-W425 HydrophobicContact CZ-CH2 4Å; F131-W425 AromaticContact CZ-CZ2 3.89Å; F131-W425 HydrophobicContact CZ-CZ2 3.89Å
132	P	67.1	Low	73.5	Confident	66 Å²	66	79.2 Å²	79.2	43%	0.429	42%	0.416	S	S	.	.	T	Hydrogen-bonded Turn	trans	-74.9	59.7	178.9	33.8	-37	0	0	0	111.1	Q418 F421	P132-Q418 PolarHBondContact O-OE1 2.95Å; P132-F421 HydrophobicContact CG-CD2 3.77Å; P132-F421 HydrophobicContact CG-CE2 4.32Å; P132-F421 HydrophobicContact CG-CG 4.16Å
133	I	64.2	Low	73	Confident	21 Å²	21	74.9 Å²	74.9	11%	0.108	40%	0.402	C	S	.	.	T	Hydrogen-bonded Turn	trans	-97.8	-27.1	-172.5	-70.9	173.7	0	0	0	111.2	F131 S135 S148 R149 V152	F131-I133 HydrophobicContact CB-CD1 3.38Å; F131-I133 HydrophobicContact CB-CG1 3.56Å; F131-I133 HydrophobicContact CD2-CD1 4.18Å; F131-I133 HydrophobicContact CG-CD1 4.13Å; F131-I133 PolarHBondContact O-N 3.25Å; I133-S135 PolarHBondContact O-N 3.07Å; I133-S135 VanDerWaalsContact O-N 3.1Å; I133-S148 WeakPolarHBondContact CG2-OG 3.48Å; I133-R149 HydrophobicContact CD1-CG 4.44Å; I133-V152 HydrophobicContact CD1-CG2 3.95Å
134	L	57.7	Low	72.5	Confident	99 Å²	99	70.5 Å²	70.5	52%	0.518	38%	0.383	S	S	.	.			trans	-79.9	100.6	-172.6	-69.6	95.4	0	0	0	110.3	P136	L134-P136 WeakPolarHBondContact O-CD 3.25Å
135	S	60.1	Low	72.2	Confident	29 Å²	29	70.6 Å²	70.6	20%	0.203	38%	0.384	C	S	.	.			trans	-68.3	118.5	148.3	-175.5	0	0	0	0	106.7	I133 K137 H138	I133-S135 PolarHBondContact O-N 3.07Å; I133-S135 VanDerWaalsContact O-N 3.1Å; S135-K137 PolarHBondContact O-N 3.36Å; S135-H138 PolarHBondContact O-N 3.18Å
136	P	58.7	Low	72.2	Confident	127 Å²	127	69.3 Å²	69.3	83%	0.825	38%	0.381	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.4	-4.3	-177	23.5	-32.1	0	0	0	113.5	L134	L134-P136 WeakPolarHBondContact O-CD 3.25Å
137	K	60.4	Low	72.3	Confident	171 Å²	171	64.1 Å²	64.1	74%	0.743	36%	0.358	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.1	-14.1	-178.6	-63.5	-176.8	179	175.7	0	114	S135	S135-K137 PolarHBondContact O-N 3.36Å
138	H	61.4	Low	72.4	Confident	71 Å²	71	60.1 Å²	60.1	33%	0.329	34%	0.337	S	S	.	.	S	Bend	trans	-114.3	135.4	-173.7	-62	127.4	0	0	0	112.7	S135 S142 E144 Q145	S135-H138 PolarHBondContact O-N 3.18Å; H138-S142 WeakPolarHBondContact CB-OG 3.33Å; H138-E144 IonicContact CE1-OE1 3.6Å; H138-E144 PolarHBondContact CE1-OE1 2.93Å; H138-E144 IonicContact CE1-OE2 3.77Å; H138-E144 PolarHBondContact CE1-OE2 3.06Å; H138-E144 IonicContact CG-OE2 2.75Å; H138-E144 IonicContact ND1-OE1 3.9Å; H138-E144 IonicContact ND1-OE2 3.2Å; H138-E144 PolarHBondContact ND1-OE2 3.27Å; H138-Q145 PolarHBondContact O-NE2 2.91Å
139	G	63.2	Low	72.9	Confident	52 Å²	52	60.9 Å²	60.9	54%	0.536	34%	0.34	S	S	.	.			trans	-61.9	161.2	178.9	0	0	0	0	0	113.1	L141 S142 Q145	G139-L141 PolarHBondContact O-N 3.26Å; G139-S142 WeakPolarHBondContact O-CB 3.49Å; G139-S142 PolarHBondContact O-N 2.83Å; G139-S142 PolarHBondContact O-OG 3.37Å; G139-Q145 PolarHBondContact O-OE1 2.95Å
140	I	65.1	Low	73.5	Confident	122 Å²	122	57.2 Å²	57.2	63%	0.626	32%	0.32	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.7	-20.9	-174	-59.7	166	0	0	0	113.6	Q145	I140-Q145 VanDerWaalsContact C-OE1 3.23Å; I140-Q145 PolarHBondContact O-OE1 2.71Å
141	L	69.5	Low	74.3	Confident	136 Å²	136	52.3 Å²	52.3	71%	0.712	29%	0.288	S	S	*	.	T	Hydrogen-bonded Turn	trans	-113.8	21.4	-178.2	-73.7	165	0	0	0	112.9	W125 G139	W125-L141 HydrophobicContact CH2-CD2 4.05Å; W125-L141 HydrophobicContact CZ2-CD2 3.66Å; G139-L141 PolarHBondContact O-N 3.26Å
142	S	79.1	Confident	75.2	Confident	23 Å²	23	51.2 Å²	51.2	16%	0.161	28%	0.284	C	S	.	.			trans	-67.8	145.6	174.4	55.1	0	0	0	0	111.6	H138 G139 E144 Q145 L146	H138-S142 WeakPolarHBondContact CB-OG 3.33Å; G139-S142 WeakPolarHBondContact O-CB 3.49Å; G139-S142 PolarHBondContact O-N 2.83Å; G139-S142 PolarHBondContact O-OG 3.37Å; S142-E144 PolarHBondContact O-N 3.25Å; S142-Q145 PolarHBondContact O-N 2.94Å; S142-Q145 VanDerWaalsContact O-N 3.14Å; S142-Q145 WeakPolarHBondContact OG-CB 3.45Å; S142-Q145 VanDerWaalsContact OG-CG 3.26Å; S142-Q145 WeakPolarHBondContact OG-CG 3.45Å; S142-L146 PolarHBondContact O-N 2.99Å; S142-L146 VanDerWaalsContact O-N 3.14Å
143	I	81.2	Confident	76.3	Confident	57 Å²	57	49.8 Å²	49.8	29%	0.292	27%	0.272	S	S	.	.	H	α-helix	trans	-54.9	-39.4	177.1	-66.9	172.6	0	0	0	110.3	L83 L146 I147	L83-I143 HydrophobicContact CD1-CG2 3.84Å; I143-L146 PolarHBondContact O-N 2.86Å; I143-I147 WeakPolarHBondContact O-CB 3.5Å; I143-I147 PolarHBondContact O-N 3.45Å
144	E	81.7	Confident	77.7	Confident	39 Å²	39	48.8 Å²	48.8	18%	0.182	27%	0.267	C	S	.	.	H	α-helix	trans	-62.7	-42.2	178.7	-56.7	-177.8	178.7	0	0	113	H138 S142 L146 I147 S148 G415	H138-E144 IonicContact CE1-OE1 3.6Å; H138-E144 PolarHBondContact CE1-OE1 2.93Å; H138-E144 IonicContact CE1-OE2 3.77Å; H138-E144 PolarHBondContact CE1-OE2 3.06Å; H138-E144 IonicContact CG-OE2 2.75Å; H138-E144 IonicContact ND1-OE1 3.9Å; H138-E144 IonicContact ND1-OE2 3.2Å; H138-E144 PolarHBondContact ND1-OE2 3.27Å; S142-E144 PolarHBondContact O-N 3.25Å; E144-L146 VanDerWaalsContact C-N 3.28Å; E144-L146 PolarHBondContact O-N 2.96Å; E144-I147 WeakPolarHBondContact O-CG2 3.19Å; E144-S148 WeakPolarHBondContact O-CB 3.31Å; E144-S148 PolarHBondContact O-N 3.37Å; E144-S148 PolarHBondContact O-OG 3.45Å; E144-G415 VanDerWaalsContact OE1-CA 3.29Å; E144-G415 WeakPolarHBondContact OE1-CA 3.36Å
145	Q	83.2	Confident	79.3	Confident	12 Å²	12	44.1 Å²	44.1	6%	0.056	24%	0.243	C	C	.	.	H	α-helix	trans	-70.2	-28.8	176.8	-75.3	-179.9	4.7	0	0	112.3	H138 G139 I140 S142 S148 R149	H138-Q145 PolarHBondContact O-NE2 2.91Å; G139-Q145 PolarHBondContact O-OE1 2.95Å; I140-Q145 VanDerWaalsContact C-OE1 3.23Å; I140-Q145 PolarHBondContact O-OE1 2.71Å; S142-Q145 PolarHBondContact O-N 2.94Å; S142-Q145 VanDerWaalsContact O-N 3.14Å; S142-Q145 WeakPolarHBondContact OG-CB 3.45Å; S142-Q145 VanDerWaalsContact OG-CG 3.26Å; S142-Q145 WeakPolarHBondContact OG-CG 3.45Å; Q145-S148 WeakPolarHBondContact CA-OG 3.23Å; Q145-S148 PolarHBondContact O-OG 3.26Å; Q145-R149 WeakPolarHBondContact O-CD 3.23Å; Q145-R149 VanDerWaalsContact O-CG 3.32Å; Q145-R149 WeakPolarHBondContact O-CG 3.41Å; Q145-R149 PolarHBondContact O-N 3.43Å
146	L	88	Confident	80.8	Confident	26 Å²	26	44.4 Å²	44.4	14%	0.136	24%	0.243	C	C	.	.	H	α-helix	trans	-77.2	-46.8	178.1	-164.9	54.6	0	0	0	111.5	L83 V87 F88 F124 S142 I143 E144 S148 R149 V150	L83-L146 HydrophobicContact CB-CD2 3.74Å; L83-L146 HydrophobicContact CB-CG 4.23Å; L83-L146 HydrophobicContact CD1-CB 4.23Å; L83-L146 HydrophobicContact CD1-CD2 4.28Å; L83-L146 HydrophobicContact CD1-CG 4.31Å; L83-L146 HydrophobicContact CD2-CG 4.17Å; L83-L146 HydrophobicContact CG-CD2 4.43Å; L83-L146 HydrophobicContact CG-CG 4.47Å; V87-L146 HydrophobicContact CB-CD1 4.08Å; V87-L146 HydrophobicContact CB-CD2 4.39Å; V87-L146 HydrophobicContact CG1-CD1 3.83Å; V87-L146 HydrophobicContact CG2-CD1 3.34Å; V87-L146 HydrophobicContact CG2-CD2 3.97Å; V87-L146 HydrophobicContact CG2-CG 3.73Å; F88-L146 HydrophobicContact CE2-CD2 4.33Å; F124-L146 HydrophobicContact CE1-CD1 3.51Å; F124-L146 HydrophobicContact CZ-CD1 3.83Å; S142-L146 PolarHBondContact O-N 2.99Å; S142-L146 VanDerWaalsContact O-N 3.14Å; I143-L146 PolarHBondContact O-N 2.86Å; E144-L146 VanDerWaalsContact C-N 3.28Å; E144-L146 PolarHBondContact O-N 2.96Å; L146-S148 PolarHBondContact O-N 3.32Å; L146-R149 PolarHBondContact O-N 2.99Å; L146-V150 WeakPolarHBondContact O-CG2 3.4Å; L146-V150 PolarHBondContact O-N 3.44Å
147	I	88.5	Confident	82.3	Confident	1 Å²	1	40.4 Å²	40.4	1%	0.005	22%	0.215	C	C	.	.	H	α-helix	trans	-64	-34.1	178.6	-144.9	156.3	0	0	0	111.3	L79 L83 I143 E144 G151 V392 L414 L417	L79-I147 HydrophobicContact CD1-CD1 3.81Å; L79-I147 HydrophobicContact CD2-CD1 3.48Å; L79-I147 VanDerWaalsContact CD2-CD1 3.48Å; L79-I147 HydrophobicContact CG-CD1 4.16Å; L83-I147 HydrophobicContact CD1-CB 4.2Å; L83-I147 HydrophobicContact CD1-CD1 4.36Å; L83-I147 HydrophobicContact CD1-CG1 4.38Å; L83-I147 HydrophobicContact CD2-CB 4.38Å; L83-I147 HydrophobicContact CD2-CG1 4.24Å; I143-I147 WeakPolarHBondContact O-CB 3.5Å; I143-I147 PolarHBondContact O-N 3.45Å; E144-I147 WeakPolarHBondContact O-CG2 3.19Å; I147-G151 WeakPolarHBondContact O-CA 3.45Å; I147-G151 PolarHBondContact O-N 2.88Å; I147-V392 HydrophobicContact CG1-CG1 3.9Å; I147-L414 HydrophobicContact CD1-CD2 3.37Å; I147-L414 HydrophobicContact CG1-CD2 4.25Å; I147-L417 HydrophobicContact CG2-CD1 3.59Å; I147-L417 HydrophobicContact CG2-CD2 4.36Å
148	S	86.5	Confident	83.6	Confident	0 Å²	0	33.9 Å²	33.9	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-67.7	-42.6	179.8	46	0	0	0	0	112.6	I133 E144 Q145 L146 G151 V152 Y422	I133-S148 WeakPolarHBondContact CG2-OG 3.48Å; E144-S148 WeakPolarHBondContact O-CB 3.31Å; E144-S148 PolarHBondContact O-N 3.37Å; E144-S148 PolarHBondContact O-OG 3.45Å; Q145-S148 WeakPolarHBondContact CA-OG 3.23Å; Q145-S148 PolarHBondContact O-OG 3.26Å; L146-S148 PolarHBondContact O-N 3.32Å; S148-G151 PolarHBondContact O-N 3.24Å; S148-V152 WeakPolarHBondContact O-CG2 3.43Å; S148-V152 PolarHBondContact O-N 2.73Å; S148-Y422 VanDerWaalsContact C-OH 3.27Å; S148-Y422 WeakPolarHBondContact CA-OH 3.49Å; S148-Y422 WeakPolarHBondContact CB-OH 3.26Å; S148-Y422 PolarHBondContact O-OH 2.88Å
149	R	89.5	Confident	85	Confident	17 Å²	17	30.5 Å²	30.5	6%	0.064	17%	0.172	C	C	.	.	H	α-helix	trans	-69.2	-46.4	176.8	-69.2	171.8	178.3	-178	-7.1	112.1	F124 W125 I133 Q145 L146 G151 V152 I153	F124-R149 HydrophobicContact CE1-CB 4.14Å; F124-R149 HydrophobicContact CE2-CB 4.08Å; F124-R149 HydrophobicContact CZ-CB 3.6Å; W125-R149 VanDerWaalsContact CD2-NH1 3.27Å; W125-R149 VanDerWaalsContact NE1-NH1 3.13Å; W125-R149 PolarHBondContact O-NH2 2.97Å; I133-R149 HydrophobicContact CD1-CG 4.44Å; Q145-R149 WeakPolarHBondContact O-CD 3.23Å; Q145-R149 VanDerWaalsContact O-CG 3.32Å; Q145-R149 WeakPolarHBondContact O-CG 3.41Å; Q145-R149 PolarHBondContact O-N 3.43Å; L146-R149 PolarHBondContact O-N 2.99Å; R149-G151 PolarHBondContact O-N 3.4Å; R149-V152 PolarHBondContact O-N 3.05Å; R149-I153 WeakPolarHBondContact O-CG1 3.49Å; R149-I153 PolarHBondContact O-N 3.16Å
150	V	91.5	Very high	86.4	Confident	1 Å²	1	31.7 Å²	31.7	1%	0.006	17%	0.165	C	C	.	.	H	α-helix	trans	-56.7	-43.2	171.6	170.1	0	0	0	0	110	L83 L86 V87 F124 L146 V152 I153 G154 M389 V392	L83-V150 HydrophobicContact CD2-CB 4.27Å; L83-V150 HydrophobicContact CD2-CG2 3.93Å; L86-V150 HydrophobicContact CD1-CG1 4.19Å; V87-V150 HydrophobicContact CG2-CG2 3.91Å; F124-V150 HydrophobicContact CE2-CG2 4.24Å; F124-V150 HydrophobicContact CZ-CG2 3.97Å; L146-V150 WeakPolarHBondContact O-CG2 3.4Å; L146-V150 PolarHBondContact O-N 3.44Å; V150-V152 PolarHBondContact O-N 3.37Å; V150-I153 PolarHBondContact O-N 2.79Å; V150-G154 PolarHBondContact O-N 3.43Å; V150-M389 HydrophobicContact CG1-CB 4.42Å; V150-M389 HydrophobicContact CG1-CG 4.12Å; V150-V392 HydrophobicContact CG1-CB 4Å; V150-V392 HydrophobicContact CG1-CG1 3.84Å; V150-V392 HydrophobicContact CG1-CG2 4.32Å
151	G	90.6	Very high	87.5	Confident	0 Å²	0	29.2 Å²	29.2	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-57.2	-45.3	176.8	0	0	0	0	0	113.1	I147 S148 R149 G154 V155 S393	I147-G151 WeakPolarHBondContact O-CA 3.45Å; I147-G151 PolarHBondContact O-N 2.88Å; S148-G151 PolarHBondContact O-N 3.24Å; R149-G151 PolarHBondContact O-N 3.4Å; G151-G154 PolarHBondContact O-N 3.33Å; G151-V155 VanDerWaalsContact O-CB 3.28Å; G151-V155 WeakPolarHBondContact O-CB 3.44Å; G151-V155 WeakPolarHBondContact O-CG2 3.48Å; G151-V155 PolarHBondContact O-N 3.49Å; G151-S393 WeakPolarHBondContact CA-OG 3.49Å; G151-S393 PolarHBondContact O-OG 3.34Å
152	V	91	Very high	88.4	Confident	5 Å²	5	24.3 Å²	24.3	3%	0.03	13%	0.13	C	C	.	.	H	α-helix	trans	-61	-47.4	177.8	171	0	0	0	0	110.7	F131 I133 S148 R149 V150 V155 T156 F421 Y422	F131-V152 HydrophobicContact CD2-CG1 4.17Å; F131-V152 HydrophobicContact CD2-CG2 4.18Å; F131-V152 HydrophobicContact CE1-CG1 4.29Å; F131-V152 HydrophobicContact CE2-CG1 3.6Å; F131-V152 HydrophobicContact CE2-CG2 4.43Å; F131-V152 HydrophobicContact CG-CG2 4.36Å; F131-V152 HydrophobicContact CZ-CG1 3.65Å; I133-V152 HydrophobicContact CD1-CG2 3.95Å; S148-V152 WeakPolarHBondContact O-CG2 3.43Å; S148-V152 PolarHBondContact O-N 2.73Å; R149-V152 PolarHBondContact O-N 3.05Å; V150-V152 PolarHBondContact O-N 3.37Å; V152-V155 PolarHBondContact O-N 3.39Å; V152-T156 WeakPolarHBondContact O-CB 3.21Å; V152-T156 PolarHBondContact O-N 2.85Å; V152-T156 PolarHBondContact O-OG1 2.85Å; V152-F421 HydrophobicContact CG2-CE1 3.94Å; V152-Y422 HydrophobicContact CG2-CE1 3.92Å
153	I	91.7	Very high	88.9	Confident	37 Å²	37	23.2 Å²	23.2	19%	0.19	12%	0.123	C	C	.	.	H	α-helix	trans	-64.4	-47.7	-178	-59.8	167.9	0	0	0	110	F124 L127 R149 V150 V155 T156 L157 M389	F124-I153 HydrophobicContact CD2-CD1 3.99Å; F124-I153 HydrophobicContact CE2-CD1 3.87Å; L127-I153 HydrophobicContact CD2-CD1 3.76Å; L127-I153 HydrophobicContact CD2-CG1 3.61Å; R149-I153 WeakPolarHBondContact O-CG1 3.49Å; R149-I153 PolarHBondContact O-N 3.16Å; V150-I153 PolarHBondContact O-N 2.79Å; I153-V155 PolarHBondContact O-N 2.89Å; I153-T156 WeakPolarHBondContact O-CB 3.3Å; I153-T156 PolarHBondContact O-N 3.45Å; I153-L157 HydrophobicContact CG2-CD1 4.22Å; I153-L157 WeakPolarHBondContact O-CG 3.48Å; I153-L157 PolarHBondContact O-N 2.86Å; I153-M389 HydrophobicContact CB-SD 3.99Å; I153-M389 HydrophobicContact CD1-SD 4.27Å; I153-M389 HydrophobicContact CG2-CE 3.61Å; I153-M389 HydrophobicContact CG2-SD 3.51Å; I153-M389 VanDerWaalsContact CG2-SD 3.51Å
154	G	92.2	Very high	89.3	Confident	0 Å²	0	25.3 Å²	25.3	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-67.6	-34.9	179.5	0	0	0	0	0	113.4	V150 G151 T156 L157 M158 S393	V150-G154 PolarHBondContact O-N 3.43Å; G151-G154 PolarHBondContact O-N 3.33Å; G154-T156 VanDerWaalsContact C-N 3.34Å; G154-L157 PolarHBondContact O-N 2.88Å; G154-M158 WeakPolarHBondContact O-CB 3.39Å; G154-M158 PolarHBondContact O-N 3.39Å; G154-S393 VanDerWaalsContact C-CB 3.43Å; G154-S393 WeakPolarHBondContact CA-OG 3.21Å
155	V	91.4	Very high	89.6	Confident	0 Å²	0	24.5 Å²	24.5	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-66.1	-40.5	173.6	168.3	0	0	0	0	110	G151 V152 I153 M158 A159 S393 L397 Y422 F426	G151-V155 VanDerWaalsContact O-CB 3.28Å; G151-V155 WeakPolarHBondContact O-CB 3.44Å; G151-V155 WeakPolarHBondContact O-CG2 3.48Å; G151-V155 PolarHBondContact O-N 3.49Å; V152-V155 PolarHBondContact O-N 3.39Å; I153-V155 PolarHBondContact O-N 2.89Å; V155-M158 PolarHBondContact O-N 3.2Å; V155-A159 WeakPolarHBondContact O-CB 3.36Å; V155-A159 PolarHBondContact O-N 2.92Å; V155-S393 PolarHBondContact N-OG 3.27Å; V155-L397 HydrophobicContact CG2-CD1 4.13Å; V155-L397 HydrophobicContact CG2-CD2 4.44Å; V155-L397 HydrophobicContact CG2-CG 4.27Å; V155-Y422 HydrophobicContact CG2-CD1 3.99Å; V155-F426 HydrophobicContact CG1-CB 3.72Å; V155-F426 HydrophobicContact CG1-CD2 4.14Å; V155-F426 HydrophobicContact CG1-CG 4.45Å
156	T	92.6	Very high	89.8	Confident	35 Å²	35	24.4 Å²	24.4	22%	0.215	13%	0.133	C	C	.	.	H	α-helix	trans	-59	-49	174.5	-53.7	0	0	0	0	110.5	V152 I153 G154 M158 A159 L160 W425 I429	V152-T156 WeakPolarHBondContact O-CB 3.21Å; V152-T156 PolarHBondContact O-N 2.85Å; V152-T156 PolarHBondContact O-OG1 2.85Å; I153-T156 WeakPolarHBondContact O-CB 3.3Å; I153-T156 PolarHBondContact O-N 3.45Å; G154-T156 VanDerWaalsContact C-N 3.34Å; T156-M158 PolarHBondContact O-N 3.45Å; T156-A159 PolarHBondContact O-N 3.24Å; T156-L160 HydrophobicContact CG2-CD1 4.15Å; T156-L160 HydrophobicContact CG2-CG 4.44Å; T156-L160 WeakPolarHBondContact O-CB 3.37Å; T156-L160 VanDerWaalsContact O-CG 3.23Å; T156-L160 WeakPolarHBondContact O-CG 3.26Å; T156-L160 PolarHBondContact O-N 2.95Å; T156-W425 PolarHBondContact OG1-NE1 3.1Å; T156-I429 HydrophobicContact CG2-CG1 4.41Å; T156-I429 HydrophobicContact CG2-CG2 4.06Å
157	L	89	Confident	89.9	Confident	43 Å²	43	24 Å²	24	23%	0.225	13%	0.132	C	C	.	.	H	α-helix	trans	-61.2	-46	177.6	-70.5	168.2	0	0	0	112.1	I153 G154 A159 L160 L161 I386 M389	I153-L157 HydrophobicContact CG2-CD1 4.22Å; I153-L157 WeakPolarHBondContact O-CG 3.48Å; I153-L157 PolarHBondContact O-N 2.86Å; G154-L157 PolarHBondContact O-N 2.88Å; L157-A159 VanDerWaalsContact C-N 3.34Å; L157-A159 PolarHBondContact O-N 3.44Å; L157-L160 PolarHBondContact O-N 2.98Å; L157-L161 WeakPolarHBondContact O-CB 3.22Å; L157-L161 WeakPolarHBondContact O-CG 3.31Å; L157-L161 PolarHBondContact O-N 2.8Å; L157-I386 HydrophobicContact CD1-CB 4.48Å; L157-I386 HydrophobicContact CD1-CG1 4.24Å; L157-I386 HydrophobicContact CD1-CG2 4.22Å; L157-M389 HydrophobicContact CD1-CE 3.75Å
158	M	88.3	Confident	89.8	Confident	34 Å²	34	26.3 Å²	26.3	17%	0.167	14%	0.144	C	C	.	.	H	α-helix	trans	-62.8	-41.6	178.3	-172.6	-176	173	0	0	111.6	G154 V155 T156 S162 Y390 L397 F426	G154-M158 WeakPolarHBondContact O-CB 3.39Å; G154-M158 PolarHBondContact O-N 3.39Å; V155-M158 PolarHBondContact O-N 3.2Å; T156-M158 PolarHBondContact O-N 3.45Å; M158-S162 WeakPolarHBondContact O-CB 3.35Å; M158-S162 PolarHBondContact O-N 2.94Å; M158-S162 PolarHBondContact O-OG 2.67Å; M158-Y390 HydrophobicContact CB-CD2 4.02Å; M158-Y390 HydrophobicContact CB-CE2 3.88Å; M158-Y390 HydrophobicContact CG-CD2 4.29Å; M158-Y390 HydrophobicContact CG-CE2 3.67Å; M158-L397 HydrophobicContact CE-CD1 4.25Å; M158-L397 HydrophobicContact SD-CD1 3.56Å; M158-L397 VanDerWaalsContact SD-CD1 3.56Å; M158-F426 HydrophobicContact CB-CE2 4.38Å; M158-F426 HydrophobicContact CE-CE2 4.41Å; M158-F426 HydrophobicContact CG-CE2 3.96Å; M158-F426 HydrophobicContact SD-CE2 4.22Å
159	A	91.7	Very high	89.6	Confident	0 Å²	0	28.9 Å²	28.9	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-68.2	-42.2	178.8	0	0	0	0	0	112.1	V155 T156 L157 S162 G163 F426 I429 F430	V155-A159 WeakPolarHBondContact O-CB 3.36Å; V155-A159 PolarHBondContact O-N 2.92Å; T156-A159 PolarHBondContact O-N 3.24Å; L157-A159 VanDerWaalsContact C-N 3.34Å; L157-A159 PolarHBondContact O-N 3.44Å; A159-S162 PolarHBondContact O-N 3.17Å; A159-G163 PolarHBondContact O-N 2.84Å; A159-F426 HydrophobicContact CB-CD2 3.67Å; A159-F426 HydrophobicContact CB-CE2 3.9Å; A159-F426 HydrophobicContact CB-CG 4.15Å; A159-F426 WeakPolarHBondContact CB-O 3.43Å; A159-I429 HydrophobicContact CB-CB 3.7Å; A159-I429 HydrophobicContact CB-CG2 3.63Å; A159-F430 HydrophobicContact CB-CB 4.34Å
160	L	91.7	Very high	89.4	Confident	77 Å²	77	28.6 Å²	28.6	40%	0.403	16%	0.162	S	C	.	.	H	α-helix	trans	-60.6	-49	174	-72.2	174.2	0	0	0	111.4	T156 L157 S162 G163 F164 I429 S433	T156-L160 HydrophobicContact CG2-CD1 4.15Å; T156-L160 HydrophobicContact CG2-CG 4.44Å; T156-L160 WeakPolarHBondContact O-CB 3.37Å; T156-L160 VanDerWaalsContact O-CG 3.23Å; T156-L160 WeakPolarHBondContact O-CG 3.26Å; T156-L160 PolarHBondContact O-N 2.95Å; L157-L160 PolarHBondContact O-N 2.98Å; L160-S162 VanDerWaalsContact C-N 3.31Å; L160-S162 PolarHBondContact O-N 2.89Å; L160-G163 PolarHBondContact O-N 3.5Å; L160-F164 WeakPolarHBondContact O-CB 3.2Å; L160-F164 PolarHBondContact O-N 2.9Å; L160-I429 HydrophobicContact CD2-CG2 3.75Å; L160-I429 HydrophobicContact CG-CG2 3.74Å; L160-S433 PolarHBondContact O-OG 2.9Å
161	L	87.7	Confident	89.1	Confident	70 Å²	70	31.2 Å²	31.2	37%	0.366	17%	0.172	S	C	.	.	H	α-helix	trans	-65.1	-38	178.3	-69.2	175.2	0	0	0	111.8	L157 G165 T362	L157-L161 WeakPolarHBondContact O-CB 3.22Å; L157-L161 WeakPolarHBondContact O-CG 3.31Å; L157-L161 PolarHBondContact O-N 2.8Å; L161-G165 PolarHBondContact O-N 3.3Å; L161-T362 HydrophobicContact CD1-CG2 4.36Å; L161-T362 HydrophobicContact CD2-CG2 4.06Å
162	S	88.7	Confident	88.7	Confident	34 Å²	34	34 Å²	34	24%	0.238	19%	0.189	C	C	.	.	H	α-helix	trans	-67.8	-41.2	177.2	-63.7	0	0	0	0	112.2	M158 A159 L160 G165 A166 F430	M158-S162 WeakPolarHBondContact O-CB 3.35Å; M158-S162 PolarHBondContact O-N 2.94Å; M158-S162 PolarHBondContact O-OG 2.67Å; A159-S162 PolarHBondContact O-N 3.17Å; L160-S162 VanDerWaalsContact C-N 3.31Å; L160-S162 PolarHBondContact O-N 2.89Å; S162-G165 PolarHBondContact O-N 3.34Å; S162-A166 WeakPolarHBondContact O-CB 3.42Å; S162-A166 PolarHBondContact O-N 3.01Å; S162-F430 WeakPolarHBondContact O-CE2 3.37Å
163	G	90.6	Very high	88.2	Confident	0 Å²	0	38.1 Å²	38.1	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-67	-47.1	178.8	0	0	0	0	0	111.6	A159 L160 G165 A166	A159-G163 PolarHBondContact O-N 2.84Å; L160-G163 PolarHBondContact O-N 3.5Å; G163-G165 PolarHBondContact O-N 3.29Å; G163-A166 PolarHBondContact O-N 3.29Å
164	F	89.7	Confident	87.7	Confident	100 Å²	100	37.2 Å²	37.2	44%	0.439	20%	0.2	S	C	.	.	H	α-helix	trans	-58.5	-46.9	171.6	177.6	-99.9	0	0	0	111.7	L160 A166 V167 N168 S433	L160-F164 WeakPolarHBondContact O-CB 3.2Å; L160-F164 PolarHBondContact O-N 2.9Å; F164-A166 VanDerWaalsContact C-N 3.34Å; F164-A166 PolarHBondContact O-N 2.89Å; F164-V167 PolarHBondContact O-N 3.27Å; F164-N168 HydrophobicContact CD1-CB 4.22Å; F164-N168 HydrophobicContact CE1-CB 3.83Å; F164-N168 HydrophobicContact CE2-CB 4.28Å; F164-N168 HydrophobicContact CZ-CB 3.86Å; F164-N168 VanDerWaalsContact O-CB 3.24Å; F164-N168 WeakPolarHBondContact O-CB 3.39Å; F164-N168 PolarHBondContact O-N 3.33Å; F164-S433 PolarHBondContact N-OG 2.87Å
165	G	87.4	Confident	87	Confident	22 Å²	22	39.2 Å²	39.2	23%	0.227	21%	0.214	C	C	.	.	H	α-helix	trans	-62.1	-37.3	178.8	0	0	0	0	0	113.5	L161 S162 G163 V167 C169	L161-G165 PolarHBondContact O-N 3.3Å; S162-G165 PolarHBondContact O-N 3.34Å; G163-G165 PolarHBondContact O-N 3.29Å; G165-V167 PolarHBondContact O-N 3.24Å; G165-C169 WeakPolarHBondContact O-CB 3.49Å; G165-C169 PolarHBondContact O-N 3.5Å; G165-C169 PolarHBondContact O-SG 3.01Å
166	A	88.1	Confident	86.4	Confident	10 Å²	10	47.5 Å²	47.5	8%	0.083	25%	0.246	C	C	.	.	H	α-helix	trans	-62.4	-26.1	178.3	0	0	0	0	0	113	S162 G163 F164 P170 C297 F430	S162-A166 WeakPolarHBondContact O-CB 3.42Å; S162-A166 PolarHBondContact O-N 3.01Å; G163-A166 PolarHBondContact O-N 3.29Å; F164-A166 VanDerWaalsContact C-N 3.34Å; F164-A166 PolarHBondContact O-N 2.89Å; A166-P170 VanDerWaalsContact O-CD 3.22Å; A166-P170 WeakPolarHBondContact O-CD 3.29Å; A166-P170 WeakPolarHBondContact O-CG 3.43Å; A166-C297 VanDerWaalsContact CA-SG 3.57Å; A166-C297 HydrophobicContact CB-CB 4.13Å; A166-C297 VanDerWaalsContact O-CB 3.24Å; A166-C297 WeakPolarHBondContact O-CB 3.28Å; A166-C297 PolarHBondContact O-SG 3.44Å; A166-F430 HydrophobicContact CB-CE2 3.92Å; A166-F430 HydrophobicContact CB-CZ 3.88Å
167	V	89.8	Confident	85.8	Confident	18 Å²	18	49.5 Å²	49.5	11%	0.109	25%	0.252	C	S	.	.	H	α-helix	trans	-98.3	-45.8	179.3	-173	0	0	0	0	110.8	F164 G165 C169 P170 Y171 A434 I438 L441	F164-V167 PolarHBondContact O-N 3.27Å; G165-V167 PolarHBondContact O-N 3.24Å; V167-C169 PolarHBondContact O-N 3.41Å; V167-P170 WeakPolarHBondContact O-CD 3.46Å; V167-Y171 WeakPolarHBondContact O-CB 3.27Å; V167-Y171 PolarHBondContact O-N 2.87Å; V167-A434 HydrophobicContact CG2-CB 4.06Å; V167-A434 WeakPolarHBondContact CG2-O 3.19Å; V167-I438 HydrophobicContact CB-CG1 4.38Å; V167-I438 HydrophobicContact CG1-CG1 3.64Å; V167-I438 HydrophobicContact CG2-CD1 4.21Å; V167-I438 HydrophobicContact CG2-CG1 3.74Å; V167-L441 HydrophobicContact CG1-CD1 3.6Å
168	N	86.8	Confident	85.2	Confident	50 Å²	50	48.7 Å²	48.7	27%	0.267	25%	0.248	S	C	.	.	H	α-helix	trans	-69.8	-31.4	-175.2	-170	55.6	0	0	0	112.9	F164 Y171 T172	F164-N168 HydrophobicContact CD1-CB 4.22Å; F164-N168 HydrophobicContact CE1-CB 3.83Å; F164-N168 HydrophobicContact CE2-CB 4.28Å; F164-N168 HydrophobicContact CZ-CB 3.86Å; F164-N168 VanDerWaalsContact O-CB 3.24Å; F164-N168 WeakPolarHBondContact O-CB 3.39Å; F164-N168 PolarHBondContact O-N 3.33Å; N168-Y171 PolarHBondContact O-N 3.21Å; N168-T172 VanDerWaalsContact O-CB 3.3Å; N168-T172 WeakPolarHBondContact O-CB 3.48Å; N168-T172 PolarHBondContact O-N 2.9Å; N168-T172 PolarHBondContact O-OG1 2.91Å
169	C	82.3	Confident	84.6	Confident	53 Å²	53	49 Å²	49	36%	0.358	25%	0.247	S	C	.	.	H	α-helix	trans	-65.6	-54.8	178.5	-73	0	0	0	0	112.2	G165 V167 Y171 T172 Y173	G165-C169 WeakPolarHBondContact O-CB 3.49Å; G165-C169 PolarHBondContact O-N 3.5Å; G165-C169 PolarHBondContact O-SG 3.01Å; V167-C169 PolarHBondContact O-N 3.41Å; C169-Y171 VanDerWaalsContact C-N 3.29Å; C169-Y171 PolarHBondContact O-N 3.24Å; C169-T172 PolarHBondContact O-N 3.34Å; C169-Y173 PolarHBondContact O-N 3.2Å
170	P	84.9	Confident	84	Confident	11 Å²	11	55.7 Å²	55.7	7%	0.071	28%	0.283	C	S	.	.	H	α-helix	trans	-55.3	-43.2	171.6	-27.9	35.8	0	0	0	113	A166 V167 T172 Y173 M174 C297	A166-P170 VanDerWaalsContact O-CD 3.22Å; A166-P170 WeakPolarHBondContact O-CD 3.29Å; A166-P170 WeakPolarHBondContact O-CG 3.43Å; V167-P170 WeakPolarHBondContact O-CD 3.46Å; P170-T172 VanDerWaalsContact C-N 3.3Å; P170-T172 PolarHBondContact O-N 3.41Å; P170-Y173 PolarHBondContact O-N 3.44Å; P170-M174 WeakPolarHBondContact O-CB 3.33Å; P170-M174 PolarHBondContact O-N 3.39Å; P170-C297 HydrophobicContact CG-CB 4.44Å
171	Y	84.6	Confident	83.5	Confident	57 Å²	57	52.9 Å²	52.9	22%	0.224	27%	0.269	C	S	.	.	H	α-helix	trans	-59.3	-39.4	178.4	-179.3	-104.4	0	0	0	112.8	V167 N168 C169 F177 L441	V167-Y171 WeakPolarHBondContact O-CB 3.27Å; V167-Y171 PolarHBondContact O-N 2.87Å; N168-Y171 PolarHBondContact O-N 3.21Å; C169-Y171 VanDerWaalsContact C-N 3.29Å; C169-Y171 PolarHBondContact O-N 3.24Å; Y171-F177 HydrophobicContact CD2-CB 3.8Å; Y171-F177 HydrophobicContact CD2-CD1 4.33Å; Y171-F177 HydrophobicContact CD2-CD2 4.13Å; Y171-F177 AromaticContact CD2-CG 3.86Å; Y171-F177 HydrophobicContact CD2-CG 3.86Å; Y171-F177 HydrophobicContact CE2-CB 3.92Å; Y171-F177 HydrophobicContact CE2-CG 4.3Å; Y171-L441 HydrophobicContact CD1-CD1 4.18Å; Y171-L441 HydrophobicContact CD1-CD2 3.86Å; Y171-L441 HydrophobicContact CD2-CD1 4.06Å; Y171-L441 HydrophobicContact CD2-CD2 4.4Å; Y171-L441 HydrophobicContact CE1-CD2 3.74Å; Y171-L441 HydrophobicContact CE2-CD2 4.3Å; Y171-L441 HydrophobicContact CG-CD1 3.79Å; Y171-L441 HydrophobicContact CG-CD2 4.2Å
172	T	82.3	Confident	83.5	Confident	58 Å²	58	52.7 Å²	52.7	36%	0.356	27%	0.271	S	S	.	.	H	α-helix	trans	-79.8	-35.7	-178.5	-57.3	0	0	0	0	113	N168 C169 P170	N168-T172 VanDerWaalsContact O-CB 3.3Å; N168-T172 WeakPolarHBondContact O-CB 3.48Å; N168-T172 PolarHBondContact O-N 2.9Å; N168-T172 PolarHBondContact O-OG1 2.91Å; C169-T172 PolarHBondContact O-N 3.34Å; P170-T172 VanDerWaalsContact C-N 3.3Å; P170-T172 PolarHBondContact O-N 3.41Å
173	Y	80	Confident	83.6	Confident	91 Å²	91	55.4 Å²	55.4	36%	0.357	28%	0.283	S	S	.	.	H	α-helix	trans	-87.5	-30.5	-174.8	-73.5	-7.4	0	0	0	113.8	C169 P170 S175 F286 N287 F293	C169-Y173 PolarHBondContact O-N 3.2Å; P170-Y173 PolarHBondContact O-N 3.44Å; Y173-S175 PolarHBondContact O-N 3.02Å; Y173-F286 HydrophobicContact CD1-CD1 4.34Å; Y173-F286 HydrophobicContact CD2-CD1 4.32Å; Y173-F286 AromaticContact CE1-CD1 4Å; Y173-F286 HydrophobicContact CE1-CD1 4Å; Y173-F286 HydrophobicContact CE1-CE1 4.45Å; Y173-F286 AromaticContact CE2-CD1 3.99Å; Y173-F286 HydrophobicContact CE2-CD1 3.99Å; Y173-F286 HydrophobicContact CE2-CE1 4.43Å; Y173-F286 AromaticContact CZ-CD1 3.81Å; Y173-N287 WeakPolarHBondContact O-CA 3.24Å; Y173-F293 HydrophobicContact CD2-CD2 4.3Å; Y173-F293 HydrophobicContact CE2-CD2 4.4Å; Y173-F293 HydrophobicContact CE2-CE2 4.38Å
174	M	81.1	Confident	83.5	Confident	18 Å²	18	60.1 Å²	60.1	9%	0.089	31%	0.312	C	S	.	.			trans	-81.1	122.5	-174.2	-160.6	169.1	79.9	0	0	111	P170 Y176 F177 N287 Y291	P170-M174 WeakPolarHBondContact O-CB 3.33Å; P170-M174 PolarHBondContact O-N 3.39Å; M174-Y176 VanDerWaalsContact CE-CB 3.48Å; M174-Y176 HydrophobicContact CE-CD1 3.44Å; M174-Y176 VanDerWaalsContact CE-CD1 3.44Å; M174-Y176 HydrophobicContact CE-CE1 4.46Å; M174-Y176 HydrophobicContact CE-CG 3.74Å; M174-Y176 PolarHBondContact O-N 3.06Å; M174-F177 HydrophobicContact CB-CD2 4.08Å; M174-F177 HydrophobicContact CE-CD2 3.45Å; M174-F177 VanDerWaalsContact CE-CD2 3.45Å; M174-F177 HydrophobicContact CE-CE1 4.32Å; M174-F177 HydrophobicContact CE-CE2 3.12Å; M174-F177 HydrophobicContact CE-CG 4.19Å; M174-F177 HydrophobicContact CE-CZ 3.61Å; M174-F177 PolarHBondContact O-N 2.92Å; M174-F177 HydrophobicContact SD-CE2 4.37Å; M174-N287 WeakPolarHBondContact CA-OD1 3.3Å; M174-Y291 HydrophobicContact CG-CE1 4.08Å; M174-Y291 HydrophobicContact CG-CE2 4.25Å; M174-Y291 HydrophobicContact SD-CD1 3.81Å; M174-Y291 HydrophobicContact SD-CE1 3.48Å; M174-Y291 WeakPolarHBondContact SD-CE1 3.13Å
175	S	77.4	Confident	83.5	Confident	42 Å²	42	57.2 Å²	57.2	29%	0.294	30%	0.301	S	S	.	.	G	3₁₀ helix	trans	-63.5	-22.7	178.2	64.5	0	0	0	0	113	Y173 F177 L178 N287	Y173-S175 PolarHBondContact O-N 3.02Å; S175-F177 VanDerWaalsContact C-N 3.25Å; S175-F177 PolarHBondContact O-N 3.3Å; S175-L178 VanDerWaalsContact O-CB 3.31Å; S175-L178 WeakPolarHBondContact O-CB 3.42Å; S175-L178 PolarHBondContact O-N 3Å; S175-L178 VanDerWaalsContact O-N 3.11Å; S175-N287 PolarHBondContact N-OD1 3.44Å; S175-N287 PolarHBondContact OG-ND2 2.87Å; S175-N287 VanDerWaalsContact OG-ND2 3.1Å; S175-N287 PolarHBondContact OG-OD1 3.28Å
176	Y	79.2	Confident	83.6	Confident	175 Å²	175	56.4 Å²	56.4	69%	0.686	29%	0.291	S	S	*	.	G	3₁₀ helix	trans	-61.6	-29.9	176.9	179	-90.2	0	0	0	113.4	M174 L178	M174-Y176 VanDerWaalsContact CE-CB 3.48Å; M174-Y176 HydrophobicContact CE-CD1 3.44Å; M174-Y176 VanDerWaalsContact CE-CD1 3.44Å; M174-Y176 HydrophobicContact CE-CE1 4.46Å; M174-Y176 HydrophobicContact CE-CG 3.74Å; M174-Y176 PolarHBondContact O-N 3.06Å; Y176-L178 VanDerWaalsContact C-N 3.34Å
177	F	80	Confident	83.8	Confident	76 Å²	76	59.9 Å²	59.9	33%	0.333	31%	0.308	S	S	.	.	G	3₁₀ helix	trans	-89.9	2.4	176.7	-66.3	-59.2	0	0	0	113.2	Y171 M174 S175 R179	Y171-F177 HydrophobicContact CD2-CB 3.8Å; Y171-F177 HydrophobicContact CD2-CD1 4.33Å; Y171-F177 HydrophobicContact CD2-CD2 4.13Å; Y171-F177 AromaticContact CD2-CG 3.86Å; Y171-F177 HydrophobicContact CD2-CG 3.86Å; Y171-F177 HydrophobicContact CE2-CB 3.92Å; Y171-F177 HydrophobicContact CE2-CG 4.3Å; M174-F177 HydrophobicContact CB-CD2 4.08Å; M174-F177 HydrophobicContact CE-CD2 3.45Å; M174-F177 VanDerWaalsContact CE-CD2 3.45Å; M174-F177 HydrophobicContact CE-CE1 4.32Å; M174-F177 HydrophobicContact CE-CE2 3.12Å; M174-F177 HydrophobicContact CE-CG 4.19Å; M174-F177 HydrophobicContact CE-CZ 3.61Å; M174-F177 PolarHBondContact O-N 2.92Å; M174-F177 HydrophobicContact SD-CE2 4.37Å; S175-F177 VanDerWaalsContact C-N 3.25Å; S175-F177 PolarHBondContact O-N 3.3Å; F177-R179 PolarHBondContact O-N 3.45Å
178	L	76.9	Confident	83.9	Confident	27 Å²	27	61.6 Å²	61.6	14%	0.141	32%	0.324	C	S	.	.	S	Bend	trans	-74.9	121.2	173.7	-68.4	165.7	0	0	0	109.1	S175 Y176 N180 R274 I275	S175-L178 VanDerWaalsContact O-CB 3.31Å; S175-L178 WeakPolarHBondContact O-CB 3.42Å; S175-L178 PolarHBondContact O-N 3Å; S175-L178 VanDerWaalsContact O-N 3.11Å; Y176-L178 VanDerWaalsContact C-N 3.34Å; L178-N180 PolarHBondContact O-N 3Å; L178-R274 HydrophobicContact CD2-CB 3.76Å; L178-I275 HydrophobicContact CB-CG1 4.5Å; L178-I275 HydrophobicContact CD1-CG1 4.44Å
179	R	76.5	Confident	84.1	Confident	40 Å²	40	59.9 Å²	59.9	15%	0.151	32%	0.315	C	S	.	.			trans	-57.2	133.4	166.2	165.3	166.1	174	-162.7	-0.1	109.1	F177 V181 T271 E450	F177-R179 PolarHBondContact O-N 3.45Å; R179-V181 HydrophobicContact CG-CG2 3.94Å; R179-V181 PolarHBondContact O-N 3.1Å; R179-T271 HydrophobicContact CB-CG2 4.44Å; R179-E450 WeakPolarHBondContact CB-OE1 3.15Å; R179-E450 HydrophobicContact CG-CG 4.42Å; R179-E450 WeakPolarHBondContact CG-OE1 2.98Å
180	N	79	Confident	84.7	Confident	140 Å²	140	60.2 Å²	60.2	75%	0.749	31%	0.311	S	S	*	.			trans	-71.6	114.9	171.8	-71	-41.3	0	0	0	108.5	L178	L178-N180 PolarHBondContact O-N 3Å
181	V	81.7	Confident	85.2	Confident	18 Å²	18	67.6 Å²	67.6	11%	0.109	34%	0.337	C	S	.	.			trans	-115.6	122.2	176.9	-179.9	0	0	0	0	108.2	R179 I186 L268 T271 I275	R179-V181 HydrophobicContact CG-CG2 3.94Å; R179-V181 PolarHBondContact O-N 3.1Å; V181-I186 HydrophobicContact CG1-CD1 3.96Å; V181-I186 HydrophobicContact CG1-CG1 3.76Å; V181-L268 HydrophobicContact CB-CD2 4.5Å; V181-L268 HydrophobicContact CG1-CB 4.2Å; V181-L268 HydrophobicContact CG1-CD2 3.96Å; V181-L268 HydrophobicContact CG2-CD2 3.68Å; V181-T271 HydrophobicContact CG2-CG2 3.64Å; V181-I275 HydrophobicContact CB-CD1 4.25Å
182	T	86.9	Confident	85.6	Confident	66 Å²	66	71.1 Å²	71.1	41%	0.405	35%	0.35	S	S	.	.			trans	-96.5	156.2	173.8	64.3	0	0	0	0	110.8	T184 D185 I186	T182-T184 WeakPolarHBondContact CB-OG1 3.39Å; T182-T184 PolarHBondContact O-N 3.48Å; T182-T184 PolarHBondContact OG1-OG1 3.2Å; T182-D185 PolarHBondContact N-OD2 2.63Å; T182-D185 WeakPolarHBondContact O-CB 3.39Å; T182-D185 PolarHBondContact O-N 2.9Å; T182-D185 PolarHBondContact OG1-N 3.39Å; T182-D185 PolarHBondContact OG1-OD1 3.25Å; T182-D185 PolarHBondContact OG1-OD2 2.86Å; T182-I186 PolarHBondContact O-N 2.91Å
183	D	89.9	Confident	86.1	Confident	92 Å²	92	69.1 Å²	69.1	49%	0.492	34%	0.337	S	S	.	.	H	α-helix	trans	-59.5	-29.9	174.6	-70.3	-33.9	0	0	0	112.1	D185 I186 L187 K272	D183-D185 VanDerWaalsContact C-N 3.35Å; D183-I186 PolarHBondContact O-N 3.24Å; D183-L187 WeakPolarHBondContact O-CB 3.41Å; D183-L187 VanDerWaalsContact O-CG 3.25Å; D183-L187 WeakPolarHBondContact O-CG 3.09Å; D183-L187 PolarHBondContact O-N 3.41Å; D183-K272 VanDerWaalsContact OD1-CE 3.26Å; D183-K272 WeakPolarHBondContact OD1-CE 3.19Å; D183-K272 IonicContact OD1-NZ 2.61Å; D183-K272 PolarHBondContact OD1-NZ 3.47Å; D183-K272 IonicContact OD2-NZ 3.06Å
184	T	90	Very high	86.9	Confident	99 Å²	99	69.8 Å²	69.8	61%	0.607	35%	0.346	S	S	*	.	H	α-helix	trans	-65.2	-35.9	174.5	40.4	0	0	0	0	112.7	T182 A188	T182-T184 WeakPolarHBondContact CB-OG1 3.39Å; T182-T184 PolarHBondContact O-N 3.48Å; T182-T184 PolarHBondContact OG1-OG1 3.2Å; T184-A188 VanDerWaalsContact O-CB 3.28Å; T184-A188 WeakPolarHBondContact O-CB 3.29Å; T184-A188 PolarHBondContact O-N 3.39Å
185	D	88.3	Confident	87.5	Confident	39 Å²	39	74.9 Å²	74.9	21%	0.209	37%	0.37	C	S	.	.	H	α-helix	trans	-67.6	-43.9	178.1	-56.5	-37.3	0	0	0	111	T182 D183 A188 L189	T182-D185 PolarHBondContact N-OD2 2.63Å; T182-D185 WeakPolarHBondContact O-CB 3.39Å; T182-D185 PolarHBondContact O-N 2.9Å; T182-D185 PolarHBondContact OG1-N 3.39Å; T182-D185 PolarHBondContact OG1-OD1 3.25Å; T182-D185 PolarHBondContact OG1-OD2 2.86Å; D183-D185 VanDerWaalsContact C-N 3.35Å; D185-A188 PolarHBondContact O-N 2.98Å; D185-L189 PolarHBondContact O-N 2.63Å; D185-L189 VanDerWaalsContact O-N 3.07Å
186	I	90.1	Very high	88.4	Confident	4 Å²	4	73.3 Å²	73.3	2%	0.021	36%	0.359	C	S	.	.	H	α-helix	trans	-61.6	-51.2	176.8	-62.3	176.8	0	0	0	109.6	V181 T182 D183 A188 L189 E190 L268 Y269 K272	V181-I186 HydrophobicContact CG1-CD1 3.96Å; V181-I186 HydrophobicContact CG1-CG1 3.76Å; T182-I186 PolarHBondContact O-N 2.91Å; D183-I186 PolarHBondContact O-N 3.24Å; I186-A188 VanDerWaalsContact C-N 3.29Å; I186-A188 PolarHBondContact O-N 3.47Å; I186-L189 PolarHBondContact O-N 3.45Å; I186-L189 VanDerWaalsContact O-N 3.17Å; I186-E190 HydrophobicContact CG2-CG 4.29Å; I186-E190 WeakPolarHBondContact O-CB 3.47Å; I186-E190 WeakPolarHBondContact O-CG 3.4Å; I186-E190 PolarHBondContact O-N 3.03Å; I186-L268 HydrophobicContact CG1-CB 4.02Å; I186-L268 HydrophobicContact CG1-CD1 4.41Å; I186-Y269 HydrophobicContact CD1-CD1 4.44Å; I186-Y269 HydrophobicContact CD1-CE1 4.48Å; I186-Y269 HydrophobicContact CG2-CD2 4.12Å; I186-Y269 HydrophobicContact CG2-CE1 4.02Å; I186-Y269 HydrophobicContact CG2-CE2 3.45Å; I186-Y269 VanDerWaalsContact CG2-CE2 3.45Å; I186-Y269 WeakPolarHBondContact CG2-OH 3.27Å; I186-K272 HydrophobicContact CD1-CB 4.05Å; I186-K272 HydrophobicContact CD1-CD 3.61Å; I186-K272 HydrophobicContact CD1-CG 4.42Å
187	L	93.2	Very high	89.1	Confident	83 Å²	83	68.7 Å²	68.7	44%	0.435	34%	0.344	S	S	.	.	H	α-helix	trans	-61.4	-36.5	179.6	-72.8	171.4	0	0	0	112.5	D183 R191	D183-L187 WeakPolarHBondContact O-CB 3.41Å; D183-L187 VanDerWaalsContact O-CG 3.25Å; D183-L187 WeakPolarHBondContact O-CG 3.09Å; D183-L187 PolarHBondContact O-N 3.41Å; L187-R191 WeakPolarHBondContact O-CB 3.46Å; L187-R191 WeakPolarHBondContact O-CG 3.25Å; L187-R191 PolarHBondContact O-N 2.95Å
188	A	91.7	Very high	89.9	Confident	54 Å²	54	70.1 Å²	70.1	45%	0.446	36%	0.356	S	S	.	.	H	α-helix	trans	-64.8	-43.2	176.5	0	0	0	0	0	111.5	T184 D185 I186 R192	T184-A188 VanDerWaalsContact O-CB 3.28Å; T184-A188 WeakPolarHBondContact O-CB 3.29Å; T184-A188 PolarHBondContact O-N 3.39Å; D185-A188 PolarHBondContact O-N 2.98Å; I186-A188 VanDerWaalsContact C-N 3.29Å; I186-A188 PolarHBondContact O-N 3.47Å; A188-R192 PolarHBondContact O-N 3.03Å; A188-R192 VanDerWaalsContact O-N 3.11Å
189	L	91.1	Very high	90.7	Very high	15 Å²	15	73.5 Å²	73.5	8%	0.079	37%	0.372	C	S	.	.	H	α-helix	trans	-71	-40.1	178.9	-164.6	67.7	0	0	0	112.2	D185 I186 R191 R192 L193 L261 E264 T265 L268	D185-L189 PolarHBondContact O-N 2.63Å; D185-L189 VanDerWaalsContact O-N 3.07Å; I186-L189 PolarHBondContact O-N 3.45Å; I186-L189 VanDerWaalsContact O-N 3.17Å; L189-R191 PolarHBondContact O-N 3.07Å; L189-R192 WeakPolarHBondContact O-CB 3.34Å; L189-R192 PolarHBondContact O-N 3.29Å; L189-R192 VanDerWaalsContact O-N 3.17Å; L189-L193 PolarHBondContact O-N 3.41Å; L189-L261 HydrophobicContact CD1-CD2 3.57Å; L189-L261 HydrophobicContact CG-CD2 4.49Å; L189-E264 HydrophobicContact CD2-CB 3.82Å; L189-E264 HydrophobicContact CD2-CG 3.58Å; L189-T265 WeakPolarHBondContact CD2-OG1 3.29Å; L189-L268 HydrophobicContact CB-CD1 4.43Å; L189-L268 HydrophobicContact CD2-CD1 3.7Å; L189-L268 HydrophobicContact CD2-CG 4.46Å
190	E	93.4	Very high	91.5	Very high	59 Å²	59	72.3 Å²	72.3	28%	0.276	37%	0.368	S	S	.	.	H	α-helix	trans	-59.4	-45	173	-76	-168.8	134.9	0	0	111.8	I186 R192 L193 L194 T265 Y269	I186-E190 HydrophobicContact CG2-CG 4.29Å; I186-E190 WeakPolarHBondContact O-CB 3.47Å; I186-E190 WeakPolarHBondContact O-CG 3.4Å; I186-E190 PolarHBondContact O-N 3.03Å; E190-R192 VanDerWaalsContact C-N 3.3Å; E190-R192 PolarHBondContact O-N 2.74Å; E190-L193 WeakPolarHBondContact O-CB 3.48Å; E190-L193 PolarHBondContact O-N 2.97Å; E190-L194 WeakPolarHBondContact O-CG 3.25Å; E190-L194 PolarHBondContact O-N 3.43Å; E190-T265 HydrophobicContact CG-CG2 3.86Å; E190-Y269 VanDerWaalsContact CD-OH 3.31Å; E190-Y269 HydrophobicContact CG-CE2 4.49Å; E190-Y269 PolarHBondContact OE1-OH 2.92Å
191	R	95.1	Very high	92.3	Very high	166 Å²	166	70.7 Å²	70.7	63%	0.626	36%	0.359	S	S	*	.	H	α-helix	trans	-59.1	-42.7	174.7	-75.7	174.1	-168.5	178.2	5.3	111.4	L187 L189 L194 Q195	L187-R191 WeakPolarHBondContact O-CB 3.46Å; L187-R191 WeakPolarHBondContact O-CG 3.25Å; L187-R191 PolarHBondContact O-N 2.95Å; L189-R191 PolarHBondContact O-N 3.07Å; R191-L194 PolarHBondContact O-N 3.2Å; R191-Q195 WeakPolarHBondContact O-CB 3.21Å; R191-Q195 WeakPolarHBondContact O-CG 3.43Å; R191-Q195 PolarHBondContact O-N 3.38Å
192	R	93.5	Very high	92.9	Very high	132 Å²	132	72.4 Å²	72.4	50%	0.498	37%	0.371	S	S	.	.	H	α-helix	trans	-64.9	-39.5	177.2	-171.6	178.5	179.4	-175.1	0.3	112	A188 L189 E190 T196 L261	A188-R192 PolarHBondContact O-N 3.03Å; A188-R192 VanDerWaalsContact O-N 3.11Å; L189-R192 WeakPolarHBondContact O-CB 3.34Å; L189-R192 PolarHBondContact O-N 3.29Å; L189-R192 VanDerWaalsContact O-N 3.17Å; E190-R192 VanDerWaalsContact C-N 3.3Å; E190-R192 PolarHBondContact O-N 2.74Å; R192-T196 WeakPolarHBondContact O-CB 3.15Å; R192-T196 PolarHBondContact O-N 3.34Å; R192-T196 PolarHBondContact O-OG1 2.89Å; R192-L261 HydrophobicContact CG-CD1 4Å; R192-L261 HydrophobicContact CG-CD2 4.23Å
193	L	93.9	Very high	93.2	Very high	16 Å²	16	70.4 Å²	70.4	8%	0.084	36%	0.357	C	S	.	.	H	α-helix	trans	-63	-49.9	175.4	178.5	63.5	0	0	0	111	L189 E190 Q195 T196 M197 S258 L261 F262	L189-L193 PolarHBondContact O-N 3.41Å; E190-L193 WeakPolarHBondContact O-CB 3.48Å; E190-L193 PolarHBondContact O-N 2.97Å; L193-Q195 PolarHBondContact O-N 2.61Å; L193-T196 WeakPolarHBondContact O-CB 3.39Å; L193-T196 PolarHBondContact O-N 2.79Å; L193-T196 VanDerWaalsContact O-N 3.15Å; L193-M197 HydrophobicContact CD1-CE 3.93Å; L193-M197 HydrophobicContact CD2-CE 4.24Å; L193-M197 HydrophobicContact CG-CE 3.98Å; L193-M197 WeakPolarHBondContact O-CG 3.4Å; L193-M197 PolarHBondContact O-N 2.95Å; L193-S258 WeakPolarHBondContact CD1-O 3.43Å; L193-L261 HydrophobicContact CB-CB 4.34Å; L193-L261 HydrophobicContact CD1-CB 3.79Å; L193-F262 HydrophobicContact CD1-CB 4.33Å; L193-F262 HydrophobicContact CD2-CB 4.39Å; L193-F262 HydrophobicContact CD2-CD2 4.23Å
194	L	95.5	Very high	93.3	Very high	104 Å²	104	70.2 Å²	70.2	55%	0.545	35%	0.352	S	S	.	.	H	α-helix	trans	-59.9	-45.6	177.7	-71.2	172.2	0	0	0	111.8	E190 R191 T196 M197 D198	E190-L194 WeakPolarHBondContact O-CG 3.25Å; E190-L194 PolarHBondContact O-N 3.43Å; R191-L194 PolarHBondContact O-N 3.2Å; L194-T196 VanDerWaalsContact C-N 3.3Å; L194-T196 PolarHBondContact O-N 2.98Å; L194-M197 WeakPolarHBondContact O-CB 3.39Å; L194-M197 PolarHBondContact O-N 3.4Å; L194-D198 PolarHBondContact O-N 2.97Å
195	Q	95.3	Very high	93.5	Very high	125 Å²	125	72.1 Å²	72.1	58%	0.584	35%	0.351	S	S	*	.	H	α-helix	trans	-58.4	-41.3	174.4	-75.3	173.3	-6.9	0	0	112.3	R191 L193 D198 M199	R191-Q195 WeakPolarHBondContact O-CB 3.21Å; R191-Q195 WeakPolarHBondContact O-CG 3.43Å; R191-Q195 PolarHBondContact O-N 3.38Å; L193-Q195 PolarHBondContact O-N 2.61Å; Q195-D198 PolarHBondContact O-N 2.92Å; Q195-M199 WeakPolarHBondContact O-CG 3.36Å; Q195-M199 PolarHBondContact O-N 2.91Å
196	T	94.3	Very high	93.6	Very high	9 Å²	9	76 Å²	76	6%	0.055	36%	0.363	C	S	.	.	H	α-helix	trans	-65.9	-42	177.4	-56.3	0	0	0	0	110.9	R192 L193 L194 M199 I200 L254 L257 L261	R192-T196 WeakPolarHBondContact O-CB 3.15Å; R192-T196 PolarHBondContact O-N 3.34Å; R192-T196 PolarHBondContact O-OG1 2.89Å; L193-T196 WeakPolarHBondContact O-CB 3.39Å; L193-T196 PolarHBondContact O-N 2.79Å; L193-T196 VanDerWaalsContact O-N 3.15Å; L194-T196 VanDerWaalsContact C-N 3.3Å; L194-T196 PolarHBondContact O-N 2.98Å; T196-M199 WeakPolarHBondContact O-CB 3.4Å; T196-M199 PolarHBondContact O-N 3.18Å; T196-I200 HydrophobicContact CG2-CD1 4.25Å; T196-I200 VanDerWaalsContact O-CG1 3.3Å; T196-I200 WeakPolarHBondContact O-CG1 3.26Å; T196-I200 PolarHBondContact O-N 3.2Å; T196-L254 HydrophobicContact CG2-CD2 4.19Å; T196-L257 HydrophobicContact CG2-CD2 4.15Å; T196-L257 HydrophobicContact CG2-CG 4.34Å; T196-L261 WeakPolarHBondContact OG1-CD1 3.33Å
197	M	95.1	Very high	93.4	Very high	78 Å²	78	76.9 Å²	76.9	38%	0.384	37%	0.367	S	S	.	.	H	α-helix	trans	-60.8	-43.7	174.2	-70.9	-176.4	174.5	0	0	111.9	L193 L194 M199 I200 I201	L193-M197 HydrophobicContact CD1-CE 3.93Å; L193-M197 HydrophobicContact CD2-CE 4.24Å; L193-M197 HydrophobicContact CG-CE 3.98Å; L193-M197 WeakPolarHBondContact O-CG 3.4Å; L193-M197 PolarHBondContact O-N 2.95Å; L194-M197 WeakPolarHBondContact O-CB 3.39Å; L194-M197 PolarHBondContact O-N 3.4Å; M197-M199 VanDerWaalsContact C-N 3.33Å; M197-M199 PolarHBondContact O-N 3.15Å; M197-I200 WeakPolarHBondContact O-CB 3.5Å; M197-I200 PolarHBondContact O-N 2.92Å; M197-I201 VanDerWaalsContact O-CG1 3.3Å; M197-I201 WeakPolarHBondContact O-CG1 3.31Å; M197-I201 PolarHBondContact O-N 3.2Å
198	D	96.1	Very high	93.2	Very high	107 Å²	107	75.8 Å²	75.8	57%	0.572	37%	0.371	S	S	*	.	H	α-helix	trans	-61.4	-40.5	176.2	-74.8	-27.6	0	0	0	112	L194 Q195 I201 S202	L194-D198 PolarHBondContact O-N 2.97Å; Q195-D198 PolarHBondContact O-N 2.92Å; D198-I201 PolarHBondContact O-N 2.97Å; D198-S202 WeakPolarHBondContact O-CB 3.27Å; D198-S202 PolarHBondContact O-N 3.18Å
199	M	93.6	Very high	93.1	Very high	98 Å²	98	77.9 Å²	77.9	48%	0.483	37%	0.372	S	S	.	.	H	α-helix	trans	-62.5	-43.3	174.1	-72.2	177.5	66.4	0	0	112.1	Q195 T196 M197 S202 K203 L254	Q195-M199 WeakPolarHBondContact O-CG 3.36Å; Q195-M199 PolarHBondContact O-N 2.91Å; T196-M199 WeakPolarHBondContact O-CB 3.4Å; T196-M199 PolarHBondContact O-N 3.18Å; M197-M199 VanDerWaalsContact C-N 3.33Å; M197-M199 PolarHBondContact O-N 3.15Å; M199-S202 PolarHBondContact O-N 3.36Å; M199-K203 PolarHBondContact O-N 3.48Å; M199-L254 HydrophobicContact CB-CD1 4.21Å; M199-L254 HydrophobicContact CE-CD1 4.46Å; M199-L254 HydrophobicContact CE-CD2 4.27Å
200	I	94.7	Very high	92.8	Very high	14 Å²	14	78.9 Å²	78.9	7%	0.072	38%	0.382	C	S	.	.	H	α-helix	trans	-60.9	-49.1	176.2	-67.4	163.7	0	0	0	110	T196 M197 S202 K203 K204 L254 E255	T196-I200 HydrophobicContact CG2-CD1 4.25Å; T196-I200 VanDerWaalsContact O-CG1 3.3Å; T196-I200 WeakPolarHBondContact O-CG1 3.26Å; T196-I200 PolarHBondContact O-N 3.2Å; M197-I200 WeakPolarHBondContact O-CB 3.5Å; M197-I200 PolarHBondContact O-N 2.92Å; I200-S202 VanDerWaalsContact C-N 3.33Å; I200-S202 PolarHBondContact O-N 3.42Å; I200-K203 PolarHBondContact O-N 2.64Å; I200-K204 HydrophobicContact CG2-CD 3.99Å; I200-K204 HydrophobicContact CG2-CG 4.3Å; I200-K204 WeakPolarHBondContact O-CB 3.22Å; I200-K204 WeakPolarHBondContact O-CG 3.44Å; I200-K204 PolarHBondContact O-N 3.04Å; I200-L254 HydrophobicContact CD1-CB 4.08Å; I200-L254 HydrophobicContact CG1-CB 3.55Å; I200-L254 HydrophobicContact CG1-CD1 4.32Å; I200-E255 HydrophobicContact CD1-CG 4.29Å; I200-E255 HydrophobicContact CG2-CG 4.39Å
201	I	95.3	Very high	92.3	Very high	107 Å²	107	81.7 Å²	81.7	55%	0.549	39%	0.391	S	S	.	.	H	α-helix	trans	-59.2	-45.7	179.1	-67.9	165.9	0	0	0	110.2	M197 D198 K203 K204 K205	M197-I201 VanDerWaalsContact O-CG1 3.3Å; M197-I201 WeakPolarHBondContact O-CG1 3.31Å; M197-I201 PolarHBondContact O-N 3.2Å; D198-I201 PolarHBondContact O-N 2.97Å; I201-K203 PolarHBondContact O-N 2.85Å; I201-K204 PolarHBondContact O-N 3.17Å; I201-K205 VanDerWaalsContact O-CB 3.31Å; I201-K205 WeakPolarHBondContact O-CB 3.49Å; I201-K205 PolarHBondContact O-N 3.36Å
202	S	94.2	Very high	91.8	Very high	53 Å²	53	81.9 Å²	81.9	37%	0.371	39%	0.391	S	S	.	.	H	α-helix	trans	-60.6	-44	177.3	175.3	0	0	0	0	112.8	D198 M199 I200 R206	D198-S202 WeakPolarHBondContact O-CB 3.27Å; D198-S202 PolarHBondContact O-N 3.18Å; M199-S202 PolarHBondContact O-N 3.36Å; I200-S202 VanDerWaalsContact C-N 3.33Å; I200-S202 PolarHBondContact O-N 3.42Å; S202-R206 WeakPolarHBondContact O-CG 3.46Å; S202-R206 PolarHBondContact O-N 3.49Å; S202-R206 PolarHBondContact O-NE 2.88Å; S202-R206 PolarHBondContact OG-NH2 3.43Å
203	K	92.7	Very high	91.3	Very high	24 Å²	24	78.8 Å²	78.8	10%	0.104	39%	0.387	C	S	.	.	H	α-helix	trans	-70.6	-41	177.9	-74.4	-174.1	-173.5	-82.2	0	112.2	M199 I200 I201 K205 R206 M207 I247 E250 V251 L254	M199-K203 PolarHBondContact O-N 3.48Å; I200-K203 PolarHBondContact O-N 2.64Å; I201-K203 PolarHBondContact O-N 2.85Å; K203-K205 VanDerWaalsContact C-N 3.33Å; K203-K205 PolarHBondContact O-N 3.05Å; K203-R206 WeakPolarHBondContact O-CB 3.32Å; K203-R206 PolarHBondContact O-N 3.44Å; K203-M207 WeakPolarHBondContact O-CB 3.47Å; K203-M207 PolarHBondContact O-N 2.88Å; K203-I247 HydrophobicContact CB-CG2 4.34Å; K203-E250 HydrophobicContact CD-CB 4.1Å; K203-E250 IonicContact NZ-OE1 3.01Å; K203-E250 PolarHBondContact NZ-OE1 3.35Å; K203-E250 IonicContact NZ-OE2 2.63Å; K203-E250 PolarHBondContact NZ-OE2 2.99Å; K203-V251 HydrophobicContact CB-CG2 3.64Å; K203-V251 HydrophobicContact CD-CG2 4.34Å; K203-L254 HydrophobicContact CD-CD1 3.74Å
204	K	93.2	Very high	90.4	Very high	89 Å²	89	81.6 Å²	81.6	39%	0.387	40%	0.401	S	S	.	.	H	α-helix	trans	-61.6	-40.3	173.2	-75.3	-173.5	176.4	-177.4	0	112.1	I200 I201 M207 A208 V251 E255	I200-K204 HydrophobicContact CG2-CD 3.99Å; I200-K204 HydrophobicContact CG2-CG 4.3Å; I200-K204 WeakPolarHBondContact O-CB 3.22Å; I200-K204 WeakPolarHBondContact O-CG 3.44Å; I200-K204 PolarHBondContact O-N 3.04Å; I201-K204 PolarHBondContact O-N 3.17Å; K204-M207 HydrophobicContact CG-CE 4.36Å; K204-M207 PolarHBondContact O-N 3.26Å; K204-A208 PolarHBondContact O-N 3.39Å; K204-V251 HydrophobicContact CG-CG1 4.11Å; K204-V251 HydrophobicContact CG-CG2 4.38Å; K204-E255 WeakPolarHBondContact CE-OE1 3.37Å; K204-E255 IonicContact NZ-OE1 3.86Å; K204-E255 PolarHBondContact NZ-OE1 3.46Å
205	K	93.4	Very high	89.5	Confident	138 Å²	138	84 Å²	84	60%	0.6	41%	0.407	S	S	*	.	H	α-helix	trans	-61.9	-45.4	173.3	-171.6	-179.1	179	179	0	111.3	I201 K203 M207 A208 M209	I201-K205 VanDerWaalsContact O-CB 3.31Å; I201-K205 WeakPolarHBondContact O-CB 3.49Å; I201-K205 PolarHBondContact O-N 3.36Å; K203-K205 VanDerWaalsContact C-N 3.33Å; K203-K205 PolarHBondContact O-N 3.05Å; K205-M207 PolarHBondContact O-N 3.31Å; K205-A208 PolarHBondContact O-N 2.9Å; K205-M209 HydrophobicContact CG-CE 4.16Å; K205-M209 WeakPolarHBondContact O-CG 3.31Å; K205-M209 PolarHBondContact O-N 3.38Å
206	R	89.5	Confident	88.6	Confident	122 Å²	122	82.8 Å²	82.8	46%	0.46	40%	0.401	S	S	.	.	H	α-helix	trans	-59.2	-43.4	174.5	-79.9	-177.7	-87.6	-179.9	-9.6	112.4	S202 K203 M209 A210	S202-R206 WeakPolarHBondContact O-CG 3.46Å; S202-R206 PolarHBondContact O-N 3.49Å; S202-R206 PolarHBondContact O-NE 2.88Å; S202-R206 PolarHBondContact OG-NH2 3.43Å; K203-R206 WeakPolarHBondContact O-CB 3.32Å; K203-R206 PolarHBondContact O-N 3.44Å; R206-M209 HydrophobicContact CG-CE 4.18Å; R206-M209 PolarHBondContact O-N 3.24Å; R206-A210 WeakPolarHBondContact O-CB 3.4Å; R206-A210 PolarHBondContact O-N 3.37Å
207	M	87.5	Confident	87.3	Confident	21 Å²	21	89.4 Å²	89.4	10%	0.103	43%	0.429	C	S	.	.	H	α-helix	trans	-61.9	-45.1	175.6	176	169.3	55.2	0	0	112.3	K203 K204 K205 M209 A210 R211 L244 I247 Q248	K203-M207 WeakPolarHBondContact O-CB 3.47Å; K203-M207 PolarHBondContact O-N 2.88Å; K204-M207 HydrophobicContact CG-CE 4.36Å; K204-M207 PolarHBondContact O-N 3.26Å; K205-M207 PolarHBondContact O-N 3.31Å; M207-M209 VanDerWaalsContact C-N 3.35Å; M207-M209 PolarHBondContact O-N 2.94Å; M207-A210 PolarHBondContact O-N 2.59Å; M207-R211 WeakPolarHBondContact O-CG 3.42Å; M207-R211 PolarHBondContact O-N 3.09Å; M207-L244 HydrophobicContact CB-CD1 4.4Å; M207-L244 HydrophobicContact CG-CD1 3.62Å; M207-L244 HydrophobicContact SD-CD1 4.41Å; M207-I247 HydrophobicContact CB-CG2 4.34Å; M207-Q248 PolarHBondContact SD-OE1 2.96Å
208	A	88.1	Confident	85.7	Confident	61 Å²	61	88.2 Å²	88.2	50%	0.504	44%	0.437	S	S	.	.	H	α-helix	trans	-62.8	-41	176.6	0	0	0	0	0	112	K204 K205 R212	K204-A208 PolarHBondContact O-N 3.39Å; K205-A208 PolarHBondContact O-N 2.9Å; A208-R212 WeakPolarHBondContact O-CB 3.23Å; A208-R212 PolarHBondContact O-N 3.34Å
209	M	88.8	Confident	83.6	Confident	98 Å²	98	90.5 Å²	90.5	48%	0.483	44%	0.444	S	S	.	.	H	α-helix	trans	-64.9	-44.4	174.1	-69.5	-173.5	-61.4	0	0	111.8	K205 R206 M207 R211 R212 T213	K205-M209 HydrophobicContact CG-CE 4.16Å; K205-M209 WeakPolarHBondContact O-CG 3.31Å; K205-M209 PolarHBondContact O-N 3.38Å; R206-M209 HydrophobicContact CG-CE 4.18Å; R206-M209 PolarHBondContact O-N 3.24Å; M207-M209 VanDerWaalsContact C-N 3.35Å; M207-M209 PolarHBondContact O-N 2.94Å; M209-R211 PolarHBondContact O-N 3.37Å; M209-R212 PolarHBondContact O-N 2.9Å; M209-T213 PolarHBondContact O-N 3.42Å; M209-T213 PolarHBondContact O-OG1 3.07Å
210	A	85	Confident	81.6	Confident	35 Å²	35	92 Å²	92	29%	0.289	46%	0.458	S	S	.	.	H	α-helix	trans	-61	-44.7	177.3	0	0	0	0	0	111.9	R206 M207 T213 M214 L244	R206-A210 WeakPolarHBondContact O-CB 3.4Å; R206-A210 PolarHBondContact O-N 3.37Å; M207-A210 PolarHBondContact O-N 2.59Å; A210-T213 PolarHBondContact O-N 3.29Å; A210-M214 WeakPolarHBondContact O-CG 3.47Å; A210-M214 PolarHBondContact O-N 3.16Å; A210-L244 HydrophobicContact CB-CD1 4.35Å
211	R	83.6	Confident	79.5	Confident	119 Å²	119	98 Å²	98	45%	0.449	49%	0.485	S	S	.	.	H	α-helix	trans	-60.5	-45.7	173.7	-73.1	-177.1	-174	-172.2	3.3	111.4	M207 M209 T213 M214 F215 L244	M207-R211 WeakPolarHBondContact O-CG 3.42Å; M207-R211 PolarHBondContact O-N 3.09Å; M209-R211 PolarHBondContact O-N 3.37Å; R211-T213 VanDerWaalsContact C-N 3.34Å; R211-T213 PolarHBondContact O-N 3.18Å; R211-M214 WeakPolarHBondContact O-CB 3.3Å; R211-M214 PolarHBondContact O-N 3.13Å; R211-M214 VanDerWaalsContact O-N 3.15Å; R211-F215 WeakPolarHBondContact O-CD2 3.39Å; R211-F215 PolarHBondContact O-N 3.26Å; R211-L244 HydrophobicContact CG-CD1 4.13Å; R211-L244 HydrophobicContact CG-CD2 4.08Å
212	R	84.5	Confident	77.2	Confident	170 Å²	170	99.9 Å²	99.9	64%	0.642	50%	0.497	S	S	*	.	H	α-helix	trans	-59.1	-43.5	177.1	-173.4	177.3	-179.6	173	1.9	112	A208 M209 M214 F215 Q216	A208-R212 WeakPolarHBondContact O-CB 3.23Å; A208-R212 PolarHBondContact O-N 3.34Å; M209-R212 PolarHBondContact O-N 2.9Å; R212-M214 VanDerWaalsContact C-N 3.33Å; R212-M214 PolarHBondContact O-N 2.83Å; R212-F215 PolarHBondContact O-N 2.83Å; R212-Q216 WeakPolarHBondContact O-CG 3.46Å; R212-Q216 PolarHBondContact O-N 3.21Å
213	T	82.7	Confident	74.7	Confident	66 Å²	66	106.6 Å²	106.6	41%	0.405	52%	0.519	S	S	.	.	H	α-helix	trans	-65.2	-36.2	176.3	-53.9	0	0	0	0	112	M209 A210 R211 K217	M209-T213 PolarHBondContact O-N 3.42Å; M209-T213 PolarHBondContact O-OG1 3.07Å; A210-T213 PolarHBondContact O-N 3.29Å; R211-T213 VanDerWaalsContact C-N 3.34Å; R211-T213 PolarHBondContact O-N 3.18Å; T213-K217 HydrophobicContact CG2-CD 4.37Å; T213-K217 WeakPolarHBondContact O-CB 3.24Å; T213-K217 WeakPolarHBondContact O-CG 3.36Å; T213-K217 PolarHBondContact O-N 3.39Å
214	M	75.2	Confident	72.5	Confident	76 Å²	76	108.9 Å²	108.9	37%	0.374	54%	0.537	S	S	.	.	H	α-helix	trans	-65	-43.4	173.1	-70.4	176	-171.4	0	0	112	A210 R211 R212 K217 G218 G240	A210-M214 WeakPolarHBondContact O-CG 3.47Å; A210-M214 PolarHBondContact O-N 3.16Å; R211-M214 WeakPolarHBondContact O-CB 3.3Å; R211-M214 PolarHBondContact O-N 3.13Å; R211-M214 VanDerWaalsContact O-N 3.15Å; R212-M214 VanDerWaalsContact C-N 3.33Å; R212-M214 PolarHBondContact O-N 2.83Å; M214-K217 PolarHBondContact O-N 3.33Å; M214-G218 PolarHBondContact O-N 2.86Å; M214-G240 WeakPolarHBondContact CE-O 3.34Å
215	F	76.4	Confident	70.1	Confident	155 Å²	155	111 Å²	111	68%	0.68	56%	0.563	S	S	*	*	H	α-helix	trans	-62.4	-45.4	175	-82.7	-72.1	0	0	0	112	R211 R212 K217 G218 E219	R211-F215 WeakPolarHBondContact O-CD2 3.39Å; R211-F215 PolarHBondContact O-N 3.26Å; R212-F215 PolarHBondContact O-N 2.83Å; F215-K217 PolarHBondContact O-N 2.91Å; F215-G218 PolarHBondContact O-N 3.37Å; F215-G218 VanDerWaalsContact O-N 3.14Å; F215-E219 PolarHBondContact O-N 3.2Å
216	Q	75.9	Confident	68.3	Low	98 Å²	98	106.6 Å²	106.6	46%	0.458	56%	0.556	S	S	.	*	H	α-helix	trans	-63.5	-39.2	177.5	-74.1	178.6	-22.4	0	0	112.5	R212 G218 V220	R212-Q216 WeakPolarHBondContact O-CG 3.46Å; R212-Q216 PolarHBondContact O-N 3.21Å; Q216-G218 VanDerWaalsContact C-N 3.33Å; Q216-V220 WeakPolarHBondContact O-CG2 3.33Å; Q216-V220 PolarHBondContact O-N 3.44Å
217	K	67	Low	66.8	Low	149 Å²	149	108.7 Å²	108.7	65%	0.648	57%	0.569	S	S	*	*	H	α-helix	trans	-69	-31.7	173.9	-74.6	-179	178.2	-175.5	0	112.5	T213 M214 F215 H221	T213-K217 HydrophobicContact CG2-CD 4.37Å; T213-K217 WeakPolarHBondContact O-CB 3.24Å; T213-K217 WeakPolarHBondContact O-CG 3.36Å; T213-K217 PolarHBondContact O-N 3.39Å; M214-K217 PolarHBondContact O-N 3.33Å; F215-K217 PolarHBondContact O-N 2.91Å; K217-H221 PolarHBondContact O-N 2.8Å
218	G	61.5	Low	65.3	Low	52 Å²	52	117.6 Å²	117.6	54%	0.536	60%	0.602	S	S	.	*	H	α-helix	trans	-68.4	-37.3	175	0	0	0	0	0	113.4	M214 F215 Q216	M214-G218 PolarHBondContact O-N 2.86Å; F215-G218 PolarHBondContact O-N 3.37Å; F215-G218 VanDerWaalsContact O-N 3.14Å; Q216-G218 VanDerWaalsContact C-N 3.33Å
219	E	53.4	Low	64	Low	156 Å²	156	116 Å²	116	73%	0.729	59%	0.59	S	S	*	*	H	α-helix	trans	-74.4	-31.7	177.6	-77.7	-173.5	137.3	0	0	113.3	F215 H221	F215-E219 PolarHBondContact O-N 3.2Å; E219-H221 VanDerWaalsContact C-N 3.32Å; E219-H221 PolarHBondContact O-N 2.86Å
220	V	51.9	Low	62.5	Low	128 Å²	128	116.7 Å²	116.7	78%	0.776	59%	0.594	S	S	*	*	H	α-helix	trans	-76.9	-18.6	179.6	177.4	0	0	0	0	112.4	Q216	Q216-V220 WeakPolarHBondContact O-CG2 3.33Å; Q216-V220 PolarHBondContact O-N 3.44Å
221	H	50	Low	61.3	Low	140 Å²	140	119.3 Å²	119.3	65%	0.648	60%	0.602	S	S	*	*	T	Hydrogen-bonded Turn	trans	-101.5	39.2	-177.4	-116.5	-41.3	0	0	0	114.7	K217 E219 K223	K217-H221 PolarHBondContact O-N 2.8Å; E219-H221 VanDerWaalsContact C-N 3.32Å; E219-H221 PolarHBondContact O-N 2.86Å; H221-K223 PolarHBondContact O-N 3.01Å; H221-K223 VanDerWaalsContact O-N 3.14Å
222	N	45.9	Very low	60	Low	148 Å²	148	120.7 Å²	120.7	79%	0.791	61%	0.611	S	S	*	*			trans	-81.4	83.6	163.8	-113.4	-27.4	0	0	0	110
223	K	42.6	Very low	58.6	Low	193 Å²	193	115.1 Å²	115.1	84%	0.839	60%	0.599	S	S	*	*			trans	134	91.7	163.1	-77.2	177	-176.7	179.8	0	112.9	H221	H221-K223 PolarHBondContact O-N 3.01Å; H221-K223 VanDerWaalsContact O-N 3.14Å
224	P	47.3	Very low	57.2	Low	73 Å²	73	116.7 Å²	116.7	47%	0.474	61%	0.608	S	S	.	*			trans	-106.2	100	152.8	28.4	-13.5	0	0	0	109	G226	P224-G226 PolarHBondContact O-N 3.38Å; P224-G226 VanDerWaalsContact O-N 3.12Å
225	S	41.3	Very low	56.3	Low	134 Å²	134	117.6 Å²	117.6	94%	0.937	62%	0.618	S	S	*	*			trans	-68.9	97.5	161.2	168.2	0	0	0	0	107.6
226	G	56.5	Low	55.2	Low	44 Å²	44	115 Å²	115	45%	0.454	62%	0.615	S	S	.	*	S	Bend	trans	151.3	133.7	170.1	0	0	0	0	0	115	P224 W228 G229	P224-G226 PolarHBondContact O-N 3.38Å; P224-G226 VanDerWaalsContact O-N 3.12Å; G226-W228 PolarHBondContact O-N 3.02Å; G226-W228 VanDerWaalsContact O-N 3.09Å; G226-G229 PolarHBondContact O-N 3.42Å
227	F	57.8	Low	54.2	Low	167 Å²	167	114 Å²	114	73%	0.732	62%	0.619	S	S	*	*	H	α-helix	trans	-51.6	-32.5	175.4	-137.2	-96.2	0	0	0	112.5	I231	F227-I231 HydrophobicContact CD1-CD1 4.4Å; F227-I231 WeakPolarHBondContact O-CG1 3.32Å
228	W	56.1	Low	53.6	Low	208 Å²	208	108.9 Å²	108.9	79%	0.788	60%	0.604	S	S	*	*	H	α-helix	trans	-70.3	-29.5	175.6	-90.5	94	0	0	0	114.8	G226 K232	G226-W228 PolarHBondContact O-N 3.02Å; G226-W228 VanDerWaalsContact O-N 3.09Å; W228-K232 PolarHBondContact O-N 3.3Å
229	G	59.8	Low	53.5	Low	26 Å²	26	109.6 Å²	109.6	27%	0.268	60%	0.601	S	S	.	*	H	α-helix	trans	-71.8	-33.4	176.9	0	0	0	0	0	112.3	G226 S233	G226-G229 PolarHBondContact O-N 3.42Å; G229-S233 WeakPolarHBondContact O-CB 3.3Å; G229-S233 PolarHBondContact O-N 2.84Å; G229-S233 VanDerWaalsContact O-N 3.07Å
230	M	59	Low	54	Low	114 Å²	114	103.2 Å²	103.2	56%	0.562	58%	0.578	S	S	*	*	H	α-helix	trans	-67.1	-43	177.3	-154.2	164.9	71	0	0	111	K232 S233 V234	M230-K232 PolarHBondContact O-N 3.21Å; M230-S233 PolarHBondContact O-N 2.95Å; M230-S233 PolarHBondContact O-OG 3.44Å; M230-V234 VanDerWaalsContact O-CG2 3.28Å; M230-V234 WeakPolarHBondContact O-CG2 3.46Å; M230-V234 PolarHBondContact O-N 2.81Å
231	I	58.6	Low	54.8	Low	90 Å²	90	100 Å²	100	46%	0.462	56%	0.561	S	S	.	*	H	α-helix	trans	-69	-36.3	-179.2	-53.8	161.6	0	0	0	111.8	F227 V234 T235	F227-I231 HydrophobicContact CD1-CD1 4.4Å; F227-I231 WeakPolarHBondContact O-CG1 3.32Å; I231-V234 PolarHBondContact O-N 3.32Å; I231-T235 PolarHBondContact O-N 3.1Å; I231-T235 PolarHBondContact O-OG1 3.48Å
232	K	56.2	Low	55.7	Low	147 Å²	147	99.2 Å²	99.2	64%	0.639	56%	0.557	S	S	*	*	H	α-helix	trans	-68.4	-35.7	173.5	-98.2	-173.3	175.9	-178.9	0	113.1	W228 M230 V234 T235 T236	W228-K232 PolarHBondContact O-N 3.3Å; M230-K232 PolarHBondContact O-N 3.21Å; K232-V234 VanDerWaalsContact C-N 3.33Å; K232-T235 WeakPolarHBondContact CA-OG1 3.18Å; K232-T235 PolarHBondContact O-OG1 3.35Å; K232-T236 PolarHBondContact O-N 3.11Å; K232-T236 PolarHBondContact O-OG1 3.2Å
233	S	55.9	Low	57.3	Low	54 Å²	54	96.5 Å²	96.5	38%	0.378	54%	0.543	S	S	.	.	H	α-helix	trans	-67.5	-33.8	177.5	73.4	0	0	0	0	112.4	G229 M230 S237	G229-S233 WeakPolarHBondContact O-CB 3.3Å; G229-S233 PolarHBondContact O-N 2.84Å; G229-S233 VanDerWaalsContact O-N 3.07Å; M230-S233 PolarHBondContact O-N 2.95Å; M230-S233 PolarHBondContact O-OG 3.44Å; S233-S237 VanDerWaalsContact O-CB 3.23Å; S233-S237 WeakPolarHBondContact O-CB 3.36Å; S233-S237 PolarHBondContact O-N 2.97Å; S233-S237 VanDerWaalsContact O-N 3.13Å; S233-S237 PolarHBondContact O-OG 3.41Å
234	V	53.3	Low	59.3	Low	99 Å²	99	88.8 Å²	88.8	60%	0.6	51%	0.511	S	S	*	.	H	α-helix	trans	-75.6	-38	-179.8	-179.6	0	0	0	0	111.6	M230 I231 K232 A238	M230-V234 VanDerWaalsContact O-CG2 3.28Å; M230-V234 WeakPolarHBondContact O-CG2 3.46Å; M230-V234 PolarHBondContact O-N 2.81Å; I231-V234 PolarHBondContact O-N 3.32Å; K232-V234 VanDerWaalsContact C-N 3.33Å; V234-A238 PolarHBondContact O-N 2.77Å
235	T	55.1	Low	61.1	Low	95 Å²	95	89.2 Å²	89.2	58%	0.583	51%	0.512	S	S	*	.	H	α-helix	trans	-74.4	-29.1	179.4	42.7	0	0	0	0	113.8	I231 K232	I231-T235 PolarHBondContact O-N 3.1Å; I231-T235 PolarHBondContact O-OG1 3.48Å; K232-T235 WeakPolarHBondContact CA-OG1 3.18Å; K232-T235 PolarHBondContact O-OG1 3.35Å
236	T	54.6	Low	63.4	Low	99 Å²	99	87.4 Å²	87.4	61%	0.607	49%	0.491	S	S	*	.	H	α-helix	trans	-87.5	-26.8	176.3	45.1	0	0	0	0	113.8	K232	K232-T236 PolarHBondContact O-N 3.11Å; K232-T236 PolarHBondContact O-OG1 3.2Å
237	S	54.1	Low	64.9	Low	77 Å²	77	87.1 Å²	87.1	54%	0.538	48%	0.479	S	S	.	.	H	α-helix	trans	-70.5	-33.4	177	-60.1	0	0	0	0	112.4	S233 G240 S241	S233-S237 VanDerWaalsContact O-CB 3.23Å; S233-S237 WeakPolarHBondContact O-CB 3.36Å; S233-S237 PolarHBondContact O-N 2.97Å; S233-S237 VanDerWaalsContact O-N 3.13Å; S233-S237 PolarHBondContact O-OG 3.41Å; S237-G240 PolarHBondContact O-N 3.43Å; S237-S241 PolarHBondContact O-N 2.89Å; S237-S241 PolarHBondContact O-OG 3.38Å
238	A	55.1	Low	66.5	Low	42 Å²	42	82 Å²	82	35%	0.347	46%	0.457	S	S	.	.	H	α-helix	trans	-62.8	-44.8	-179.5	0	0	0	0	0	113.1	V234 G240 S241 E242	V234-A238 PolarHBondContact O-N 2.77Å; A238-G240 VanDerWaalsContact C-N 3.31Å; A238-G240 PolarHBondContact O-N 2.77Å; A238-S241 PolarHBondContact O-N 3.36Å; A238-S241 PolarHBondContact O-OG 3.48Å; A238-E242 WeakPolarHBondContact O-CG 3.22Å; A238-E242 PolarHBondContact O-N 3.27Å
239	S	60	Low	68.2	Low	67 Å²	67	78.1 Å²	78.1	47%	0.469	45%	0.448	S	S	.	.	H	α-helix	trans	-66	-32.8	179.5	-179	0	0	0	0	112.7	N243	S239-N243 PolarHBondContact O-N 2.98Å; S239-N243 PolarHBondContact O-ND2 3.21Å
240	G	63.5	Low	69.8	Low	23 Å²	23	81.1 Å²	81.1	24%	0.237	46%	0.455	C	S	.	.	H	α-helix	trans	-68	-45.4	175.4	0	0	0	0	0	112.4	M214 S237 A238 L244	M214-G240 WeakPolarHBondContact CE-O 3.34Å; S237-G240 PolarHBondContact O-N 3.43Å; A238-G240 VanDerWaalsContact C-N 3.31Å; A238-G240 PolarHBondContact O-N 2.77Å; G240-L244 PolarHBondContact O-N 3.2Å
241	S	67.5	Low	71.4	Confident	60 Å²	60	75.7 Å²	75.7	42%	0.42	43%	0.428	S	S	.	.	H	α-helix	trans	-66.7	-40	178.5	48.4	0	0	0	0	112.9	S237 A238 L244 T245	S237-S241 PolarHBondContact O-N 2.89Å; S237-S241 PolarHBondContact O-OG 3.38Å; A238-S241 PolarHBondContact O-N 3.36Å; A238-S241 PolarHBondContact O-OG 3.48Å; S241-L244 WeakPolarHBondContact O-CB 3.27Å; S241-L244 PolarHBondContact O-N 3.46Å; S241-T245 WeakPolarHBondContact O-CG2 3.25Å; S241-T245 PolarHBondContact O-N 3.09Å; S241-T245 PolarHBondContact O-OG1 2.89Å
242	E	69.1	Low	73	Confident	123 Å²	123	75 Å²	75	58%	0.575	43%	0.426	S	S	*	.	H	α-helix	trans	-64.5	-40.7	178.2	-74.4	175.9	177.7	0	0	112.2	A238 L244 T245 L246	A238-E242 WeakPolarHBondContact O-CG 3.22Å; A238-E242 PolarHBondContact O-N 3.27Å; E242-L244 VanDerWaalsContact C-N 3.3Å; E242-L244 PolarHBondContact O-N 3.31Å; E242-T245 WeakPolarHBondContact CA-OG1 3.45Å; E242-T245 PolarHBondContact O-N 3.45Å; E242-T245 PolarHBondContact O-OG1 3.25Å; E242-L246 VanDerWaalsContact O-CG 3.32Å; E242-L246 WeakPolarHBondContact O-CG 3.49Å; E242-L246 PolarHBondContact O-N 3.38Å
243	N	80	Confident	74.8	Confident	91 Å²	91	71.1 Å²	71.1	49%	0.487	42%	0.42	S	S	.	.	H	α-helix	trans	-65.1	-35.6	174.3	-77.9	-53	0	0	0	112.1	S239 I247	S239-N243 PolarHBondContact O-N 2.98Å; S239-N243 PolarHBondContact O-ND2 3.21Å; N243-I247 WeakPolarHBondContact O-CD1 3.38Å; N243-I247 VanDerWaalsContact O-CG1 3.23Å; N243-I247 WeakPolarHBondContact O-CG1 3.33Å; N243-I247 PolarHBondContact O-N 3.43Å
244	L	84	Confident	76.7	Confident	32 Å²	32	69.6 Å²	69.6	17%	0.168	41%	0.408	C	S	.	.	H	α-helix	trans	-69.3	-40.7	178.8	-164.9	71.2	0	0	0	111.8	M207 A210 R211 G240 S241 E242 Q248	M207-L244 HydrophobicContact CB-CD1 4.4Å; M207-L244 HydrophobicContact CG-CD1 3.62Å; M207-L244 HydrophobicContact SD-CD1 4.41Å; A210-L244 HydrophobicContact CB-CD1 4.35Å; R211-L244 HydrophobicContact CG-CD1 4.13Å; R211-L244 HydrophobicContact CG-CD2 4.08Å; G240-L244 PolarHBondContact O-N 3.2Å; S241-L244 WeakPolarHBondContact O-CB 3.27Å; S241-L244 PolarHBondContact O-N 3.46Å; E242-L244 VanDerWaalsContact C-N 3.3Å; E242-L244 PolarHBondContact O-N 3.31Å; L244-Q248 WeakPolarHBondContact O-CB 3.19Å; L244-Q248 PolarHBondContact O-N 2.82Å
245	T	86.3	Confident	78.6	Confident	81 Å²	81	68.3 Å²	68.3	50%	0.497	40%	0.396	S	S	.	.	H	α-helix	trans	-68.6	-39.5	177.5	54.1	0	0	0	0	111.6	S241 E242 Q248 Q249	S241-T245 WeakPolarHBondContact O-CG2 3.25Å; S241-T245 PolarHBondContact O-N 3.09Å; S241-T245 PolarHBondContact O-OG1 2.89Å; E242-T245 WeakPolarHBondContact CA-OG1 3.45Å; E242-T245 PolarHBondContact O-N 3.45Å; E242-T245 PolarHBondContact O-OG1 3.25Å; T245-Q248 WeakPolarHBondContact O-CB 3.43Å; T245-Q248 PolarHBondContact O-N 3.47Å; T245-Q249 WeakPolarHBondContact O-CG 3.43Å; T245-Q249 PolarHBondContact O-N 3.47Å
246	L	89.5	Confident	80.4	Confident	96 Å²	96	67.1 Å²	67.1	50%	0.503	38%	0.383	S	S	.	.	H	α-helix	trans	-62	-47.5	173.9	-73	172.8	0	0	0	112	E242 Q248 Q249 E250	E242-L246 VanDerWaalsContact O-CG 3.32Å; E242-L246 WeakPolarHBondContact O-CG 3.49Å; E242-L246 PolarHBondContact O-N 3.38Å; L246-Q248 VanDerWaalsContact C-N 3.26Å; L246-Q248 PolarHBondContact O-N 2.89Å; L246-Q249 PolarHBondContact O-N 2.9Å; L246-E250 WeakPolarHBondContact O-CG 3.19Å; L246-E250 PolarHBondContact O-N 3.26Å
247	I	87.7	Confident	82.3	Confident	38 Å²	38	65 Å²	65	20%	0.195	37%	0.368	C	S	.	.	H	α-helix	trans	-62	-37.1	176.6	-67.1	166.6	0	0	0	110.7	K203 M207 N243 E250 V251	K203-I247 HydrophobicContact CB-CG2 4.34Å; M207-I247 HydrophobicContact CB-CG2 4.34Å; N243-I247 WeakPolarHBondContact O-CD1 3.38Å; N243-I247 VanDerWaalsContact O-CG1 3.23Å; N243-I247 WeakPolarHBondContact O-CG1 3.33Å; N243-I247 PolarHBondContact O-N 3.43Å; I247-E250 PolarHBondContact O-N 3.43Å; I247-V251 HydrophobicContact CG2-CG2 4.41Å; I247-V251 VanDerWaalsContact O-CG2 3.28Å; I247-V251 WeakPolarHBondContact O-CG2 3.46Å; I247-V251 PolarHBondContact O-N 2.96Å
248	Q	90.9	Very high	84.2	Confident	60 Å²	60	62.4 Å²	62.4	28%	0.28	35%	0.35	S	S	.	.	H	α-helix	trans	-62.9	-46.9	175.7	-176.5	64.3	45.9	0	0	111.3	M207 L244 T245 L246 E250 V251 D252	M207-Q248 PolarHBondContact SD-OE1 2.96Å; L244-Q248 WeakPolarHBondContact O-CB 3.19Å; L244-Q248 PolarHBondContact O-N 2.82Å; T245-Q248 WeakPolarHBondContact O-CB 3.43Å; T245-Q248 PolarHBondContact O-N 3.47Å; L246-Q248 VanDerWaalsContact C-N 3.26Å; L246-Q248 PolarHBondContact O-N 2.89Å; Q248-E250 VanDerWaalsContact C-N 3.3Å; Q248-E250 PolarHBondContact O-N 2.95Å; Q248-V251 WeakPolarHBondContact O-CB 3.41Å; Q248-V251 PolarHBondContact O-N 3.36Å; Q248-V251 VanDerWaalsContact O-N 3.11Å; Q248-D252 PolarHBondContact NE2-OD1 2.84Å; Q248-D252 PolarHBondContact O-N 2.9Å
249	Q	92.3	Very high	85.9	Confident	126 Å²	126	67.1 Å²	67.1	59%	0.589	36%	0.358	S	S	*	.	H	α-helix	trans	-60	-39.8	176.4	-72.5	176.2	-13.7	0	0	112.2	T245 L246 D252 A253	T245-Q249 WeakPolarHBondContact O-CG 3.43Å; T245-Q249 PolarHBondContact O-N 3.47Å; L246-Q249 PolarHBondContact O-N 2.9Å; Q249-D252 PolarHBondContact O-N 2.9Å; Q249-A253 WeakPolarHBondContact O-CB 3.48Å; Q249-A253 PolarHBondContact O-N 3.47Å
250	E	92.5	Very high	87.4	Confident	89 Å²	89	68.9 Å²	68.9	42%	0.416	36%	0.359	S	S	.	.	H	α-helix	trans	-65.3	-38.7	174.2	-68.3	-179.6	122.8	0	0	112.5	K203 L246 I247 Q248 L254	K203-E250 HydrophobicContact CD-CB 4.1Å; K203-E250 IonicContact NZ-OE1 3.01Å; K203-E250 PolarHBondContact NZ-OE1 3.35Å; K203-E250 IonicContact NZ-OE2 2.63Å; K203-E250 PolarHBondContact NZ-OE2 2.99Å; L246-E250 WeakPolarHBondContact O-CG 3.19Å; L246-E250 PolarHBondContact O-N 3.26Å; I247-E250 PolarHBondContact O-N 3.43Å; Q248-E250 VanDerWaalsContact C-N 3.3Å; Q248-E250 PolarHBondContact O-N 2.95Å; E250-L254 WeakPolarHBondContact O-CB 3.42Å; E250-L254 VanDerWaalsContact O-CG 3.27Å; E250-L254 WeakPolarHBondContact O-CG 3.43Å; E250-L254 PolarHBondContact O-N 2.94Å
251	V	93.4	Very high	88.8	Confident	1 Å²	1	68 Å²	68	1%	0.006	35%	0.349	C	S	.	.	H	α-helix	trans	-64.6	-46.1	175.4	168.6	0	0	0	0	110.1	K203 K204 I247 Q248 A253 L254 E255	K203-V251 HydrophobicContact CB-CG2 3.64Å; K203-V251 HydrophobicContact CD-CG2 4.34Å; K204-V251 HydrophobicContact CG-CG1 4.11Å; K204-V251 HydrophobicContact CG-CG2 4.38Å; I247-V251 HydrophobicContact CG2-CG2 4.41Å; I247-V251 VanDerWaalsContact O-CG2 3.28Å; I247-V251 WeakPolarHBondContact O-CG2 3.46Å; I247-V251 PolarHBondContact O-N 2.96Å; Q248-V251 WeakPolarHBondContact O-CB 3.41Å; Q248-V251 PolarHBondContact O-N 3.36Å; Q248-V251 VanDerWaalsContact O-N 3.11Å; V251-A253 VanDerWaalsContact C-N 3.3Å; V251-A253 PolarHBondContact O-N 3.35Å; V251-L254 PolarHBondContact O-N 3.39Å; V251-E255 HydrophobicContact CG1-CG 4.26Å; V251-E255 WeakPolarHBondContact O-CB 3.18Å; V251-E255 WeakPolarHBondContact O-CG 3.27Å; V251-E255 PolarHBondContact O-N 3.28Å
252	D	93.1	Very high	90	Very high	76 Å²	76	70.9 Å²	70.9	41%	0.406	35%	0.354	S	S	.	.	H	α-helix	trans	-60.8	-41.2	178.8	-62.2	-20.1	0	0	0	111	Q248 Q249 E255 E256	Q248-D252 PolarHBondContact NE2-OD1 2.84Å; Q248-D252 PolarHBondContact O-N 2.9Å; Q249-D252 PolarHBondContact O-N 2.9Å; D252-E255 PolarHBondContact O-N 3.22Å; D252-E256 PolarHBondContact O-N 3.33Å
253	A	93.6	Very high	91	Very high	64 Å²	64	70 Å²	70	53%	0.529	35%	0.353	S	S	.	.	H	α-helix	trans	-65.8	-41.2	175.6	0	0	0	0	0	112.9	Q249 V251 E256 L257	Q249-A253 WeakPolarHBondContact O-CB 3.48Å; Q249-A253 PolarHBondContact O-N 3.47Å; V251-A253 VanDerWaalsContact C-N 3.3Å; V251-A253 PolarHBondContact O-N 3.35Å; A253-E256 PolarHBondContact O-N 3.47Å; A253-L257 PolarHBondContact O-N 2.67Å
254	L	94.9	Very high	91.4	Very high	23 Å²	23	68.7 Å²	68.7	12%	0.12	34%	0.344	C	S	.	.	H	α-helix	trans	-69.6	-35.5	176	-73.3	170.8	0	0	0	112.1	T196 M199 I200 K203 E250 V251 L257 S258	T196-L254 HydrophobicContact CG2-CD2 4.19Å; M199-L254 HydrophobicContact CB-CD1 4.21Å; M199-L254 HydrophobicContact CE-CD1 4.46Å; M199-L254 HydrophobicContact CE-CD2 4.27Å; I200-L254 HydrophobicContact CD1-CB 4.08Å; I200-L254 HydrophobicContact CG1-CB 3.55Å; I200-L254 HydrophobicContact CG1-CD1 4.32Å; K203-L254 HydrophobicContact CD-CD1 3.74Å; E250-L254 WeakPolarHBondContact O-CB 3.42Å; E250-L254 VanDerWaalsContact O-CG 3.27Å; E250-L254 WeakPolarHBondContact O-CG 3.43Å; E250-L254 PolarHBondContact O-N 2.94Å; V251-L254 PolarHBondContact O-N 3.39Å; L254-L257 HydrophobicContact CD2-CD2 4.48Å; L254-L257 PolarHBondContact O-N 3.03Å; L254-S258 WeakPolarHBondContact O-CB 3.44Å; L254-S258 PolarHBondContact O-N 3.34Å
255	E	94	Very high	91.7	Very high	72 Å²	72	67.7 Å²	67.7	34%	0.336	34%	0.339	S	S	.	.	H	α-helix	trans	-62.6	-44.2	174.1	-77.5	-175.9	178.9	0	0	110.9	I200 K204 V251 D252 S258 R259	I200-E255 HydrophobicContact CD1-CG 4.29Å; I200-E255 HydrophobicContact CG2-CG 4.39Å; K204-E255 WeakPolarHBondContact CE-OE1 3.37Å; K204-E255 IonicContact NZ-OE1 3.86Å; K204-E255 PolarHBondContact NZ-OE1 3.46Å; V251-E255 HydrophobicContact CG1-CG 4.26Å; V251-E255 WeakPolarHBondContact O-CB 3.18Å; V251-E255 WeakPolarHBondContact O-CG 3.27Å; V251-E255 PolarHBondContact O-N 3.28Å; D252-E255 PolarHBondContact O-N 3.22Å; E255-S258 PolarHBondContact O-N 3.31Å; E255-S258 PolarHBondContact O-OG 3.48Å; E255-R259 PolarHBondContact O-N 3.43Å
256	E	92.9	Very high	91.9	Very high	70 Å²	70	66 Å²	66	33%	0.327	33%	0.334	S	S	.	.	H	α-helix	trans	-61.3	-45.3	174	-177.5	55.7	-142.4	0	0	111.8	D252 A253 S258 R259 Q260	D252-E256 PolarHBondContact O-N 3.33Å; A253-E256 PolarHBondContact O-N 3.47Å; E256-S258 VanDerWaalsContact C-N 3.33Å; E256-S258 PolarHBondContact O-N 2.88Å; E256-R259 WeakPolarHBondContact O-CB 3.1Å; E256-R259 PolarHBondContact O-N 2.95Å; E256-R259 IonicContact OE1-CZ 2.63Å; E256-R259 IonicContact OE1-NE 2.69Å; E256-R259 PolarHBondContact OE1-NE 3.28Å; E256-R259 IonicContact OE1-NH2 3.44Å; E256-R259 PolarHBondContact OE1-NH2 3.47Å; E256-R259 IonicContact OE2-CZ 3.97Å; E256-R259 IonicContact OE2-NE 2.71Å; E256-R259 PolarHBondContact OE2-NE 2.86Å; E256-R259 IonicContact OE2-NH2 3.16Å; E256-R259 PolarHBondContact OE2-NH2 3.11Å; E256-Q260 WeakPolarHBondContact O-CG 3.03Å; E256-Q260 PolarHBondContact O-N 3.4Å; E256-Q260 PolarHBondContact OE1-NE2 2.95Å
257	L	93.4	Very high	91.8	Very high	54 Å²	54	65.4 Å²	65.4	28%	0.283	33%	0.331	S	S	.	.	H	α-helix	trans	-59.9	-42.9	174.4	178.4	63.4	0	0	0	111.7	T196 A253 L254 R259 Q260 L261	T196-L257 HydrophobicContact CG2-CD2 4.15Å; T196-L257 HydrophobicContact CG2-CG 4.34Å; A253-L257 PolarHBondContact O-N 2.67Å; L254-L257 HydrophobicContact CD2-CD2 4.48Å; L254-L257 PolarHBondContact O-N 3.03Å; L257-R259 VanDerWaalsContact C-N 3.27Å; L257-R259 PolarHBondContact O-N 2.85Å; L257-Q260 PolarHBondContact O-N 3.35Å; L257-L261 HydrophobicContact CD1-CD1 4.25Å; L257-L261 HydrophobicContact CD1-CG 4.16Å; L257-L261 HydrophobicContact CG-CD1 3.97Å; L257-L261 HydrophobicContact CG-CG 4.32Å; L257-L261 WeakPolarHBondContact O-CB 3.33Å; L257-L261 WeakPolarHBondContact O-CG 3.26Å; L257-L261 PolarHBondContact O-N 3.03Å
258	S	93.4	Very high	91.8	Very high	22 Å²	22	63.8 Å²	63.8	15%	0.154	32%	0.322	C	S	.	.	H	α-helix	trans	-62.2	-37.5	178.4	77.9	0	0	0	0	111.7	L193 L254 E255 E256 F262	L193-S258 WeakPolarHBondContact CD1-O 3.43Å; L254-S258 WeakPolarHBondContact O-CB 3.44Å; L254-S258 PolarHBondContact O-N 3.34Å; E255-S258 PolarHBondContact O-N 3.31Å; E255-S258 PolarHBondContact O-OG 3.48Å; E256-S258 VanDerWaalsContact C-N 3.33Å; E256-S258 PolarHBondContact O-N 2.88Å; S258-F262 VanDerWaalsContact O-CB 3.25Å; S258-F262 WeakPolarHBondContact O-CB 3.23Å; S258-F262 PolarHBondContact O-N 3.21Å
259	R	92.2	Very high	91.8	Very high	141 Å²	141	65.7 Å²	65.7	53%	0.532	33%	0.328	S	S	.	.	H	α-helix	trans	-65.5	-44.6	175.1	-173.3	-179.4	69.3	164.5	-0.3	111.1	E255 E256 L257 F262 L263	E255-R259 PolarHBondContact O-N 3.43Å; E256-R259 WeakPolarHBondContact O-CB 3.1Å; E256-R259 PolarHBondContact O-N 2.95Å; E256-R259 IonicContact OE1-CZ 2.63Å; E256-R259 IonicContact OE1-NE 2.69Å; E256-R259 PolarHBondContact OE1-NE 3.28Å; E256-R259 IonicContact OE1-NH2 3.44Å; E256-R259 PolarHBondContact OE1-NH2 3.47Å; E256-R259 IonicContact OE2-CZ 3.97Å; E256-R259 IonicContact OE2-NE 2.71Å; E256-R259 PolarHBondContact OE2-NE 2.86Å; E256-R259 IonicContact OE2-NH2 3.16Å; E256-R259 PolarHBondContact OE2-NH2 3.11Å; L257-R259 VanDerWaalsContact C-N 3.27Å; L257-R259 PolarHBondContact O-N 2.85Å; R259-F262 PolarHBondContact O-N 3.36Å; R259-L263 HydrophobicContact CG-CD1 4.34Å; R259-L263 VanDerWaalsContact O-CG 3.3Å; R259-L263 WeakPolarHBondContact O-CG 3.47Å; R259-L263 PolarHBondContact O-N 2.84Å
260	Q	91.9	Very high	91.6	Very high	104 Å²	104	61.8 Å²	61.8	49%	0.486	32%	0.317	S	S	.	.	H	α-helix	trans	-62.8	-47.6	177.4	-69.4	175.8	7.6	0	0	111.8	E256 L257 F262 L263 E264	E256-Q260 WeakPolarHBondContact O-CG 3.03Å; E256-Q260 PolarHBondContact O-N 3.4Å; E256-Q260 PolarHBondContact OE1-NE2 2.95Å; L257-Q260 PolarHBondContact O-N 3.35Å; Q260-F262 VanDerWaalsContact C-N 3.31Å; Q260-F262 PolarHBondContact O-N 3.5Å; Q260-L263 PolarHBondContact O-N 3.43Å; Q260-E264 WeakPolarHBondContact O-CB 3.49Å; Q260-E264 PolarHBondContact O-N 2.94Å
261	L	91.9	Very high	91.3	Very high	4 Å²	4	57.8 Å²	57.8	2%	0.021	30%	0.299	C	S	.	.	H	α-helix	trans	-60.8	-39.4	176.1	-71.4	173.7	0	0	0	112	L189 R192 L193 T196 L257 E264 T265	L189-L261 HydrophobicContact CD1-CD2 3.57Å; L189-L261 HydrophobicContact CG-CD2 4.49Å; R192-L261 HydrophobicContact CG-CD1 4Å; R192-L261 HydrophobicContact CG-CD2 4.23Å; L193-L261 HydrophobicContact CB-CB 4.34Å; L193-L261 HydrophobicContact CD1-CB 3.79Å; T196-L261 WeakPolarHBondContact OG1-CD1 3.33Å; L257-L261 HydrophobicContact CD1-CD1 4.25Å; L257-L261 HydrophobicContact CD1-CG 4.16Å; L257-L261 HydrophobicContact CG-CD1 3.97Å; L257-L261 HydrophobicContact CG-CG 4.32Å; L257-L261 WeakPolarHBondContact O-CB 3.33Å; L257-L261 WeakPolarHBondContact O-CG 3.26Å; L257-L261 PolarHBondContact O-N 3.03Å; L261-E264 PolarHBondContact O-N 3.02Å; L261-T265 WeakPolarHBondContact O-CB 3.34Å; L261-T265 PolarHBondContact O-N 3.2Å; L261-T265 PolarHBondContact O-OG1 3.38Å
262	F	93.2	Very high	91	Very high	121 Å²	121	60.4 Å²	60.4	53%	0.531	31%	0.31	S	S	.	.	H	α-helix	trans	-64.1	-45.9	176.1	178.9	-96.6	0	0	0	111.9	L193 S258 R259 Q260 T265 A266	L193-F262 HydrophobicContact CD1-CB 4.33Å; L193-F262 HydrophobicContact CD2-CB 4.39Å; L193-F262 HydrophobicContact CD2-CD2 4.23Å; S258-F262 VanDerWaalsContact O-CB 3.25Å; S258-F262 WeakPolarHBondContact O-CB 3.23Å; S258-F262 PolarHBondContact O-N 3.21Å; R259-F262 PolarHBondContact O-N 3.36Å; Q260-F262 VanDerWaalsContact C-N 3.31Å; Q260-F262 PolarHBondContact O-N 3.5Å; F262-T265 PolarHBondContact O-N 2.87Å; F262-A266 WeakPolarHBondContact O-CB 3.39Å; F262-A266 PolarHBondContact O-N 2.97Å
263	L	89.8	Confident	90.8	Very high	106 Å²	106	63.3 Å²	63.3	56%	0.555	32%	0.321	S	S	*	.	H	α-helix	trans	-63.1	-42	177	-70.1	172.9	0	0	0	111.8	R259 Q260 A266 D267	R259-L263 HydrophobicContact CG-CD1 4.34Å; R259-L263 VanDerWaalsContact O-CG 3.3Å; R259-L263 WeakPolarHBondContact O-CG 3.47Å; R259-L263 PolarHBondContact O-N 2.84Å; Q260-L263 PolarHBondContact O-N 3.43Å; L263-A266 PolarHBondContact O-N 3.02Å; L263-D267 WeakPolarHBondContact O-CB 3.46Å; L263-D267 PolarHBondContact O-N 2.96Å
264	E	88.6	Confident	90.4	Very high	63 Å²	63	64.4 Å²	64.4	29%	0.294	31%	0.312	S	S	.	.	H	α-helix	trans	-65.7	-39.7	176.2	-171.3	-177.9	-176.8	0	0	111.5	L189 Q260 L261 D267 L268	L189-E264 HydrophobicContact CD2-CB 3.82Å; L189-E264 HydrophobicContact CD2-CG 3.58Å; Q260-E264 WeakPolarHBondContact O-CB 3.49Å; Q260-E264 PolarHBondContact O-N 2.94Å; L261-E264 PolarHBondContact O-N 3.02Å; E264-D267 PolarHBondContact O-N 2.93Å; E264-L268 WeakPolarHBondContact O-CG 3.1Å; E264-L268 PolarHBondContact O-N 3.47Å
265	T	89.9	Confident	90	Very high	10 Å²	10	64.9 Å²	64.9	6%	0.061	31%	0.314	C	S	.	.	H	α-helix	trans	-62.1	-46.4	174.7	-56.1	0	0	0	0	110.7	L189 E190 L261 F262 D267 L268 Y269	L189-T265 WeakPolarHBondContact CD2-OG1 3.29Å; E190-T265 HydrophobicContact CG-CG2 3.86Å; L261-T265 WeakPolarHBondContact O-CB 3.34Å; L261-T265 PolarHBondContact O-N 3.2Å; L261-T265 PolarHBondContact O-OG1 3.38Å; F262-T265 PolarHBondContact O-N 2.87Å; T265-D267 VanDerWaalsContact C-N 3.31Å; T265-D267 PolarHBondContact O-N 3.4Å; T265-L268 PolarHBondContact O-N 2.91Å; T265-Y269 HydrophobicContact CG2-CD2 3.86Å; T265-Y269 HydrophobicContact CG2-CE2 3.78Å; T265-Y269 VanDerWaalsContact O-CD2 3.29Å; T265-Y269 WeakPolarHBondContact O-CD2 3.25Å; T265-Y269 PolarHBondContact O-N 3.45Å
266	A	90.7	Very high	89.7	Confident	46 Å²	46	66.3 Å²	66.3	38%	0.38	32%	0.321	S	S	.	.	H	α-helix	trans	-60.8	-39.1	176	0	0	0	0	0	112.4	F262 L263 Y269 A270	F262-A266 WeakPolarHBondContact O-CB 3.39Å; F262-A266 PolarHBondContact O-N 2.97Å; L263-A266 PolarHBondContact O-N 3.02Å; A266-Y269 PolarHBondContact O-N 2.86Å; A266-A270 WeakPolarHBondContact O-CB 3.37Å; A266-A270 PolarHBondContact O-N 3.36Å
267	D	87.2	Confident	89.4	Confident	83 Å²	83	67.4 Å²	67.4	44%	0.444	32%	0.323	S	S	.	.	H	α-helix	trans	-66.8	-39.8	176.3	-174.5	58.5	0	0	0	112.7	L263 E264 T265 A270 T271	L263-D267 WeakPolarHBondContact O-CB 3.46Å; L263-D267 PolarHBondContact O-N 2.96Å; E264-D267 PolarHBondContact O-N 2.93Å; T265-D267 VanDerWaalsContact C-N 3.31Å; T265-D267 PolarHBondContact O-N 3.4Å; D267-A270 PolarHBondContact O-N 3.48Å; D267-T271 WeakPolarHBondContact O-CB 3.4Å; D267-T271 PolarHBondContact O-N 2.77Å; D267-T271 PolarHBondContact O-OG1 2.98Å
268	L	88.3	Confident	89	Confident	4 Å²	4	66.3 Å²	66.3	2%	0.021	32%	0.319	C	S	.	.	H	α-helix	trans	-64.3	-42.6	174.2	-70.6	-176	0	0	0	111.8	V181 I186 L189 E264 T265 T271 K272	V181-L268 HydrophobicContact CB-CD2 4.5Å; V181-L268 HydrophobicContact CG1-CB 4.2Å; V181-L268 HydrophobicContact CG1-CD2 3.96Å; V181-L268 HydrophobicContact CG2-CD2 3.68Å; I186-L268 HydrophobicContact CG1-CB 4.02Å; I186-L268 HydrophobicContact CG1-CD1 4.41Å; L189-L268 HydrophobicContact CB-CD1 4.43Å; L189-L268 HydrophobicContact CD2-CD1 3.7Å; L189-L268 HydrophobicContact CD2-CG 4.46Å; E264-L268 WeakPolarHBondContact O-CG 3.1Å; E264-L268 PolarHBondContact O-N 3.47Å; T265-L268 PolarHBondContact O-N 2.91Å; L268-T271 PolarHBondContact O-N 3.28Å; L268-K272 WeakPolarHBondContact O-CB 3.41Å; L268-K272 PolarHBondContact O-N 2.85Å
269	Y	90.9	Very high	88.7	Confident	100 Å²	100	72.1 Å²	72.1	39%	0.392	34%	0.342	S	S	.	.	H	α-helix	trans	-61.2	-45.8	174	-88.5	-71	0	0	0	112	I186 E190 T265 A266 T271 K272 E273	I186-Y269 HydrophobicContact CD1-CD1 4.44Å; I186-Y269 HydrophobicContact CD1-CE1 4.48Å; I186-Y269 HydrophobicContact CG2-CD2 4.12Å; I186-Y269 HydrophobicContact CG2-CE1 4.02Å; I186-Y269 HydrophobicContact CG2-CE2 3.45Å; I186-Y269 VanDerWaalsContact CG2-CE2 3.45Å; I186-Y269 WeakPolarHBondContact CG2-OH 3.27Å; E190-Y269 VanDerWaalsContact CD-OH 3.31Å; E190-Y269 HydrophobicContact CG-CE2 4.49Å; E190-Y269 PolarHBondContact OE1-OH 2.92Å; T265-Y269 HydrophobicContact CG2-CD2 3.86Å; T265-Y269 HydrophobicContact CG2-CE2 3.78Å; T265-Y269 VanDerWaalsContact O-CD2 3.29Å; T265-Y269 WeakPolarHBondContact O-CD2 3.25Å; T265-Y269 PolarHBondContact O-N 3.45Å; A266-Y269 PolarHBondContact O-N 2.86Å; Y269-T271 VanDerWaalsContact C-N 3.27Å; Y269-T271 PolarHBondContact O-N 3.44Å; Y269-K272 PolarHBondContact O-N 3.28Å; Y269-E273 PolarHBondContact O-N 3.41Å
270	A	87.6	Confident	88.6	Confident	45 Å²	45	68.3 Å²	68.3	37%	0.372	33%	0.334	S	S	.	.	H	α-helix	trans	-61.6	-36.8	175.7	0	0	0	0	0	111.9	A266 D267 R274	A266-A270 WeakPolarHBondContact O-CB 3.37Å; A266-A270 PolarHBondContact O-N 3.36Å; D267-A270 PolarHBondContact O-N 3.48Å; A270-R274 WeakPolarHBondContact O-CG 3.33Å; A270-R274 PolarHBondContact O-N 3.22Å
271	T	85.6	Confident	88.6	Confident	5 Å²	5	72.4 Å²	72.4	3%	0.031	35%	0.351	C	S	.	.	H	α-helix	trans	-70.7	-39.9	176.5	-62.5	0	0	0	0	112	R179 V181 D267 L268 Y269 R274 I275	R179-T271 HydrophobicContact CB-CG2 4.44Å; V181-T271 HydrophobicContact CG2-CG2 3.64Å; D267-T271 WeakPolarHBondContact O-CB 3.4Å; D267-T271 PolarHBondContact O-N 2.77Å; D267-T271 PolarHBondContact O-OG1 2.98Å; L268-T271 PolarHBondContact O-N 3.28Å; Y269-T271 VanDerWaalsContact C-N 3.27Å; Y269-T271 PolarHBondContact O-N 3.44Å; T271-R274 WeakPolarHBondContact O-CB 3.27Å; T271-R274 PolarHBondContact O-N 3.22Å; T271-R274 PolarHBondContact OG1-NH2 3.3Å; T271-I275 HydrophobicContact CG2-CD1 4.32Å; T271-I275 WeakPolarHBondContact O-CG1 3.43Å; T271-I275 PolarHBondContact O-N 2.85Å
272	K	88.8	Confident	88.4	Confident	55 Å²	55	78.4 Å²	78.4	24%	0.239	38%	0.377	C	S	.	.	H	α-helix	trans	-59.8	-46.2	172.3	179.4	178.1	170.2	-179.2	0	111.7	D183 I186 L268 Y269 R274 I275 E276	D183-K272 VanDerWaalsContact OD1-CE 3.26Å; D183-K272 WeakPolarHBondContact OD1-CE 3.19Å; D183-K272 IonicContact OD1-NZ 2.61Å; D183-K272 PolarHBondContact OD1-NZ 3.47Å; D183-K272 IonicContact OD2-NZ 3.06Å; I186-K272 HydrophobicContact CD1-CB 4.05Å; I186-K272 HydrophobicContact CD1-CD 3.61Å; I186-K272 HydrophobicContact CD1-CG 4.42Å; L268-K272 WeakPolarHBondContact O-CB 3.41Å; L268-K272 PolarHBondContact O-N 2.85Å; Y269-K272 PolarHBondContact O-N 3.28Å; K272-R274 VanDerWaalsContact C-N 3.27Å; K272-R274 PolarHBondContact O-N 2.82Å; K272-I275 WeakPolarHBondContact O-CB 3.2Å; K272-I275 PolarHBondContact O-N 3.17Å; K272-I275 VanDerWaalsContact O-N 3.1Å; K272-E276 WeakPolarHBondContact CE-OE1 3.23Å; K272-E276 PolarHBondContact O-N 3.36Å
273	E	88.4	Confident	88	Confident	137 Å²	137	72.8 Å²	72.8	64%	0.64	35%	0.353	S	S	*	.	H	α-helix	trans	-59	-40.2	175.3	-171.2	-174.9	175.3	0	0	111.3	Y269 E276 Y277	Y269-E273 PolarHBondContact O-N 3.41Å; E273-E276 PolarHBondContact O-N 3.05Å; E273-Y277 VanDerWaalsContact O-CB 3.29Å; E273-Y277 WeakPolarHBondContact O-CB 3.37Å; E273-Y277 PolarHBondContact O-N 3.25Å
274	R	85.4	Confident	88	Confident	88 Å²	88	73.8 Å²	73.8	33%	0.332	35%	0.353	S	S	.	.	H	α-helix	trans	-65.1	-38.3	174.4	-74.4	-166.9	-66.6	-176.3	-2.2	113.2	L178 A270 T271 K272 Y277 S278	L178-R274 HydrophobicContact CD2-CB 3.76Å; A270-R274 WeakPolarHBondContact O-CG 3.33Å; A270-R274 PolarHBondContact O-N 3.22Å; T271-R274 WeakPolarHBondContact O-CB 3.27Å; T271-R274 PolarHBondContact O-N 3.22Å; T271-R274 PolarHBondContact OG1-NH2 3.3Å; K272-R274 VanDerWaalsContact C-N 3.27Å; K272-R274 PolarHBondContact O-N 2.82Å; R274-Y277 PolarHBondContact O-N 3.19Å; R274-S278 WeakPolarHBondContact O-CB 3.35Å; R274-S278 PolarHBondContact O-N 3.27Å
275	I	85.7	Confident	88	Confident	32 Å²	32	77.3 Å²	77.3	16%	0.164	37%	0.365	C	S	.	.	H	α-helix	trans	-63.4	-46.3	174.5	-67.8	164.1	0	0	0	109.8	L178 V181 T271 K272 S278 K279	L178-I275 HydrophobicContact CB-CG1 4.5Å; L178-I275 HydrophobicContact CD1-CG1 4.44Å; V181-I275 HydrophobicContact CB-CD1 4.25Å; T271-I275 HydrophobicContact CG2-CD1 4.32Å; T271-I275 WeakPolarHBondContact O-CG1 3.43Å; T271-I275 PolarHBondContact O-N 2.85Å; K272-I275 WeakPolarHBondContact O-CB 3.2Å; K272-I275 PolarHBondContact O-N 3.17Å; K272-I275 VanDerWaalsContact O-N 3.1Å; I275-S278 WeakPolarHBondContact O-CB 3.42Å; I275-S278 PolarHBondContact O-N 2.89Å; I275-S278 PolarHBondContact O-OG 3.41Å; I275-K279 PolarHBondContact O-N 3Å
276	E	88	Confident	87.7	Confident	103 Å²	103	79.2 Å²	79.2	48%	0.481	37%	0.372	S	S	.	.	H	α-helix	trans	-62.3	-44.6	176.3	-70.6	177.6	-174.9	0	0	111.7	K272 E273 S278 K279	K272-E276 WeakPolarHBondContact CE-OE1 3.23Å; K272-E276 PolarHBondContact O-N 3.36Å; E273-E276 PolarHBondContact O-N 3.05Å; E276-S278 VanDerWaalsContact C-N 3.3Å; E276-S278 PolarHBondContact O-N 3.2Å; E276-K279 WeakPolarHBondContact O-CB 3.46Å; E276-K279 PolarHBondContact O-N 2.84Å; E276-K279 VanDerWaalsContact O-N 3.15Å
277	Y	86.8	Confident	87.5	Confident	92 Å²	92	78.5 Å²	78.5	36%	0.361	36%	0.362	S	S	.	.	H	α-helix	trans	-58.3	-41.6	174.3	-179.4	-100.1	0	0	0	111.8	E273 R274 K279 T280 K282 G283 F286	E273-Y277 VanDerWaalsContact O-CB 3.29Å; E273-Y277 WeakPolarHBondContact O-CB 3.37Å; E273-Y277 PolarHBondContact O-N 3.25Å; R274-Y277 PolarHBondContact O-N 3.19Å; Y277-K279 PolarHBondContact O-N 3.05Å; Y277-T280 WeakPolarHBondContact O-CB 3.18Å; Y277-T280 PolarHBondContact O-N 3.22Å; Y277-T280 PolarHBondContact O-OG1 2.85Å; Y277-K282 HydrophobicContact CE2-CD 4.02Å; Y277-K282 HydrophobicContact CE2-CG 4.39Å; Y277-K282 VanDerWaalsContact OH-CD 3.31Å; Y277-K282 WeakPolarHBondContact OH-CD 3.36Å; Y277-K282 VanDerWaalsContact OH-CE 3.22Å; Y277-K282 WeakPolarHBondContact OH-CE 3.38Å; Y277-K282 WeakPolarHBondContact OH-CG 3.38Å; Y277-G283 VanDerWaalsContact O-CA 3.3Å; Y277-G283 WeakPolarHBondContact O-CA 3.29Å; Y277-F286 HydrophobicContact CE1-CD2 4.34Å; Y277-F286 VanDerWaalsContact OH-CD2 3.26Å; Y277-F286 WeakPolarHBondContact OH-CD2 3.48Å; Y277-F286 WeakPolarHBondContact OH-CE2 3.17Å
278	S	85.2	Confident	87.6	Confident	31 Å²	31	81.4 Å²	81.4	22%	0.217	37%	0.371	C	S	.	.	H	α-helix	trans	-60.7	-27.2	179.7	80.9	0	0	0	0	113.2	R274 I275 E276 K284	R274-S278 WeakPolarHBondContact O-CB 3.35Å; R274-S278 PolarHBondContact O-N 3.27Å; I275-S278 WeakPolarHBondContact O-CB 3.42Å; I275-S278 PolarHBondContact O-N 2.89Å; I275-S278 PolarHBondContact O-OG 3.41Å; E276-S278 VanDerWaalsContact C-N 3.3Å; E276-S278 PolarHBondContact O-N 3.2Å; S278-K284 PolarHBondContact O-N 3.34Å
279	K	86.4	Confident	87.4	Confident	144 Å²	144	82.9 Å²	82.9	63%	0.626	38%	0.379	S	S	*	.	H	α-helix	trans	-75.8	-24.3	177.1	-64.8	173.5	-177.9	174.7	0	112.6	I275 E276 Y277 K284	I275-K279 PolarHBondContact O-N 3Å; E276-K279 WeakPolarHBondContact O-CB 3.46Å; E276-K279 PolarHBondContact O-N 2.84Å; E276-K279 VanDerWaalsContact O-N 3.15Å; Y277-K279 PolarHBondContact O-N 3.05Å; K279-K284 WeakPolarHBondContact O-CE 3.13Å
280	T	91.3	Very high	87.1	Confident	61 Å²	61	78.1 Å²	78.1	37%	0.374	36%	0.36	S	S	.	.	S	Bend	trans	-67.2	157.5	178.3	72.9	0	0	0	0	111.6	Y277 K282 G283 K284	Y277-T280 WeakPolarHBondContact O-CB 3.18Å; Y277-T280 PolarHBondContact O-N 3.22Å; Y277-T280 PolarHBondContact O-OG1 2.85Å; T280-K282 PolarHBondContact O-N 3.36Å; T280-G283 PolarHBondContact O-N 2.96Å; T280-G283 VanDerWaalsContact O-N 3.1Å; T280-G283 PolarHBondContact OG1-N 3.45Å; T280-K284 WeakPolarHBondContact O-CG 3.25Å; T280-K284 PolarHBondContact O-N 3.45Å
281	F	90	Very high	87.1	Confident	191 Å²	191	80.8 Å²	80.8	84%	0.838	36%	0.361	S	S	*	.	H	α-helix	trans	-55.8	-39.9	174.4	-75.4	-77.2	0	0	0	112.5	K284 Y285	F281-K284 PolarHBondContact O-N 3.21Å; F281-Y285 PolarHBondContact O-N 3.16Å
282	K	88.3	Confident	87.1	Confident	130 Å²	130	86.7 Å²	86.7	57%	0.565	39%	0.386	S	S	*	.	H	α-helix	trans	-63.6	-45.2	176.1	-167.6	-178	174.5	-174.3	0	110.9	Y277 T280 Y285 F286	Y277-K282 HydrophobicContact CE2-CD 4.02Å; Y277-K282 HydrophobicContact CE2-CG 4.39Å; Y277-K282 VanDerWaalsContact OH-CD 3.31Å; Y277-K282 WeakPolarHBondContact OH-CD 3.36Å; Y277-K282 VanDerWaalsContact OH-CE 3.22Å; Y277-K282 WeakPolarHBondContact OH-CE 3.38Å; Y277-K282 WeakPolarHBondContact OH-CG 3.38Å; T280-K282 PolarHBondContact O-N 3.36Å; K282-Y285 WeakPolarHBondContact O-CB 3.44Å; K282-Y285 PolarHBondContact O-N 2.87Å; K282-F286 HydrophobicContact CD-CE2 4.33Å; K282-F286 HydrophobicContact CG-CD2 3.96Å; K282-F286 HydrophobicContact CG-CE2 3.74Å; K282-F286 WeakPolarHBondContact O-CD2 3.22Å; K282-F286 PolarHBondContact O-N 3.39Å
283	G	86	Confident	86.9	Confident	3 Å²	3	87.7 Å²	87.7	3%	0.031	39%	0.391	C	S	.	.	H	α-helix	trans	-60.6	-45.3	175.5	0	0	0	0	0	113.3	Y277 T280 Y285 F286 N287	Y277-G283 VanDerWaalsContact O-CA 3.3Å; Y277-G283 WeakPolarHBondContact O-CA 3.29Å; T280-G283 PolarHBondContact O-N 2.96Å; T280-G283 VanDerWaalsContact O-N 3.1Å; T280-G283 PolarHBondContact OG1-N 3.45Å; G283-Y285 VanDerWaalsContact C-N 3.31Å; G283-Y285 PolarHBondContact O-N 2.94Å; G283-F286 PolarHBondContact O-N 3.34Å; G283-N287 WeakPolarHBondContact O-CB 3.41Å; G283-N287 PolarHBondContact O-N 2.87Å
284	K	88.2	Confident	86.8	Confident	127 Å²	127	82.5 Å²	82.5	55%	0.552	37%	0.37	S	S	*	.	H	α-helix	trans	-59	-41.2	175.3	-69.9	-178.5	-178.3	-179.3	0	112.3	S278 K279 T280 F281 N287 F288	S278-K284 PolarHBondContact O-N 3.34Å; K279-K284 WeakPolarHBondContact O-CE 3.13Å; T280-K284 WeakPolarHBondContact O-CG 3.25Å; T280-K284 PolarHBondContact O-N 3.45Å; F281-K284 PolarHBondContact O-N 3.21Å; K284-N287 PolarHBondContact O-N 3.38Å; K284-F288 PolarHBondContact O-N 3.32Å
285	Y	88.9	Confident	87	Confident	136 Å²	136	84 Å²	84	53%	0.533	38%	0.383	S	S	.	.	H	α-helix	trans	-63.3	-46.7	174.5	174.6	-100.7	0	0	0	112.3	F281 K282 G283 N287 F288 L289	F281-Y285 PolarHBondContact O-N 3.16Å; K282-Y285 WeakPolarHBondContact O-CB 3.44Å; K282-Y285 PolarHBondContact O-N 2.87Å; G283-Y285 VanDerWaalsContact C-N 3.31Å; G283-Y285 PolarHBondContact O-N 2.94Å; Y285-N287 VanDerWaalsContact C-N 3.32Å; Y285-N287 PolarHBondContact O-N 3.48Å; Y285-F288 PolarHBondContact O-N 3.37Å; Y285-L289 HydrophobicContact CD1-CD1 3.97Å; Y285-L289 HydrophobicContact CD1-CG 4.46Å; Y285-L289 HydrophobicContact CE1-CD1 3.32Å; Y285-L289 HydrophobicContact CE1-CG 4.03Å; Y285-L289 HydrophobicContact CE2-CG 4.43Å; Y285-L289 PolarHBondContact O-N 3.39Å
286	F	84.9	Confident	87.1	Confident	51 Å²	51	88 Å²	88	22%	0.224	40%	0.397	C	S	.	.	H	α-helix	trans	-64.2	-35.7	175.9	-82.7	-73	0	0	0	112.7	Y173 Y277 K282 G283 L289 G290	Y173-F286 HydrophobicContact CD1-CD1 4.34Å; Y173-F286 HydrophobicContact CD2-CD1 4.32Å; Y173-F286 AromaticContact CE1-CD1 4Å; Y173-F286 HydrophobicContact CE1-CD1 4Å; Y173-F286 HydrophobicContact CE1-CE1 4.45Å; Y173-F286 AromaticContact CE2-CD1 3.99Å; Y173-F286 HydrophobicContact CE2-CD1 3.99Å; Y173-F286 HydrophobicContact CE2-CE1 4.43Å; Y173-F286 AromaticContact CZ-CD1 3.81Å; Y277-F286 HydrophobicContact CE1-CD2 4.34Å; Y277-F286 VanDerWaalsContact OH-CD2 3.26Å; Y277-F286 WeakPolarHBondContact OH-CD2 3.48Å; Y277-F286 WeakPolarHBondContact OH-CE2 3.17Å; K282-F286 HydrophobicContact CD-CE2 4.33Å; K282-F286 HydrophobicContact CG-CD2 3.96Å; K282-F286 HydrophobicContact CG-CE2 3.74Å; K282-F286 WeakPolarHBondContact O-CD2 3.22Å; K282-F286 PolarHBondContact O-N 3.39Å; G283-F286 PolarHBondContact O-N 3.34Å; F286-L289 HydrophobicContact CD1-CD1 4.35Å; F286-L289 PolarHBondContact O-N 2.86Å; F286-G290 PolarHBondContact O-N 3.49Å
287	N	86.5	Confident	87.2	Confident	30 Å²	30	83.7 Å²	83.7	16%	0.16	38%	0.378	C	S	.	.	H	α-helix	trans	-62.3	-46.2	174.4	-171.6	37.7	0	0	0	111.4	Y173 M174 S175 G283 K284 Y285 L289 G290 Y291	Y173-N287 WeakPolarHBondContact O-CA 3.24Å; M174-N287 WeakPolarHBondContact CA-OD1 3.3Å; S175-N287 PolarHBondContact N-OD1 3.44Å; S175-N287 PolarHBondContact OG-ND2 2.87Å; S175-N287 VanDerWaalsContact OG-ND2 3.1Å; S175-N287 PolarHBondContact OG-OD1 3.28Å; G283-N287 WeakPolarHBondContact O-CB 3.41Å; G283-N287 PolarHBondContact O-N 2.87Å; K284-N287 PolarHBondContact O-N 3.38Å; Y285-N287 VanDerWaalsContact C-N 3.32Å; Y285-N287 PolarHBondContact O-N 3.48Å; N287-L289 PolarHBondContact O-N 3.21Å; N287-G290 WeakPolarHBondContact O-CA 3.18Å; N287-G290 PolarHBondContact O-N 3.45Å; N287-Y291 VanDerWaalsContact O-CD2 3.23Å; N287-Y291 WeakPolarHBondContact O-CD2 3.29Å; N287-Y291 PolarHBondContact O-N 2.63Å
288	F	87.9	Confident	87.4	Confident	144 Å²	144	84.1 Å²	84.1	63%	0.632	39%	0.39	S	S	*	.	H	α-helix	trans	-59.3	-45	173.9	178.9	-100.8	0	0	0	112.1	K284 Y285 G290 Y291 F292	K284-F288 PolarHBondContact O-N 3.32Å; Y285-F288 PolarHBondContact O-N 3.37Å; F288-G290 VanDerWaalsContact C-N 3.26Å; F288-G290 PolarHBondContact O-N 3.28Å; F288-Y291 PolarHBondContact O-N 2.81Å; F288-F292 PolarHBondContact O-N 2.83Å
289	L	84.3	Confident	87.6	Confident	36 Å²	36	89.9 Å²	89.9	19%	0.188	41%	0.407	C	S	.	.	H	α-helix	trans	-60.2	-36	172.6	-73.7	-178.4	0	0	0	112.4	Y285 F286 N287 Y291 F292 F293	Y285-L289 HydrophobicContact CD1-CD1 3.97Å; Y285-L289 HydrophobicContact CD1-CG 4.46Å; Y285-L289 HydrophobicContact CE1-CD1 3.32Å; Y285-L289 HydrophobicContact CE1-CG 4.03Å; Y285-L289 HydrophobicContact CE2-CG 4.43Å; Y285-L289 PolarHBondContact O-N 3.39Å; F286-L289 HydrophobicContact CD1-CD1 4.35Å; F286-L289 PolarHBondContact O-N 2.86Å; N287-L289 PolarHBondContact O-N 3.21Å; L289-Y291 VanDerWaalsContact C-N 3.3Å; L289-Y291 PolarHBondContact O-N 3.38Å; L289-F292 PolarHBondContact O-N 2.88Å; L289-F293 HydrophobicContact CB-CD2 4.18Å; L289-F293 HydrophobicContact CB-CE2 4.1Å; L289-F293 WeakPolarHBondContact O-CB 3.31Å; L289-F293 WeakPolarHBondContact O-CD2 3.47Å; L289-F293 PolarHBondContact O-N 2.68Å
290	G	84.6	Confident	87.6	Confident	0 Å²	0	85.6 Å²	85.6	0%	0	39%	0.388	C	S	.	.	H	α-helix	trans	-56.4	-42.6	175.5	0	0	0	0	0	112.5	F286 N287 F288 S294	F286-G290 PolarHBondContact O-N 3.49Å; N287-G290 WeakPolarHBondContact O-CA 3.18Å; N287-G290 PolarHBondContact O-N 3.45Å; F288-G290 VanDerWaalsContact C-N 3.26Å; F288-G290 PolarHBondContact O-N 3.28Å; G290-S294 WeakPolarHBondContact O-CB 3.45Å; G290-S294 PolarHBondContact O-N 3.04Å
291	Y	86.9	Confident	87.6	Confident	101 Å²	101	84.1 Å²	84.1	40%	0.396	38%	0.378	S	S	.	.	H	α-helix	trans	-66.2	-42.2	174.1	-71.9	-74.5	0	0	0	112.9	M174 N287 F288 L289 S294 I295	M174-Y291 HydrophobicContact CG-CE1 4.08Å; M174-Y291 HydrophobicContact CG-CE2 4.25Å; M174-Y291 HydrophobicContact SD-CD1 3.81Å; M174-Y291 HydrophobicContact SD-CE1 3.48Å; M174-Y291 WeakPolarHBondContact SD-CE1 3.13Å; N287-Y291 VanDerWaalsContact O-CD2 3.23Å; N287-Y291 WeakPolarHBondContact O-CD2 3.29Å; N287-Y291 PolarHBondContact O-N 2.63Å; F288-Y291 PolarHBondContact O-N 2.81Å; L289-Y291 VanDerWaalsContact C-N 3.3Å; L289-Y291 PolarHBondContact O-N 3.38Å; Y291-S294 PolarHBondContact O-N 2.71Å; Y291-S294 PolarHBondContact O-OG 3.44Å; Y291-I295 WeakPolarHBondContact O-CG1 3.45Å; Y291-I295 PolarHBondContact O-N 3.36Å; Y291-I295 VanDerWaalsContact O-N 3.15Å
292	F	87.6	Confident	87.6	Confident	128 Å²	128	80.4 Å²	80.4	56%	0.561	36%	0.362	S	S	*	.	H	α-helix	trans	-63	-46.3	176.3	-179.7	-94.8	0	0	0	111.5	F288 L289 S294 I295 Y296	F288-F292 PolarHBondContact O-N 2.83Å; L289-F292 PolarHBondContact O-N 2.88Å; F292-S294 VanDerWaalsContact C-N 3.32Å; F292-S294 PolarHBondContact O-N 3.44Å; F292-I295 PolarHBondContact O-N 3.48Å; F292-Y296 PolarHBondContact O-N 3.17Å
293	F	83.4	Confident	87.5	Confident	76 Å²	76	76.9 Å²	76.9	33%	0.333	35%	0.348	S	S	.	.	H	α-helix	trans	-65.2	-34.8	176.9	-74.9	-54.9	0	0	0	112.2	Y173 L289 Y296 C297	Y173-F293 HydrophobicContact CD2-CD2 4.3Å; Y173-F293 HydrophobicContact CE2-CD2 4.4Å; Y173-F293 HydrophobicContact CE2-CE2 4.38Å; L289-F293 HydrophobicContact CB-CD2 4.18Å; L289-F293 HydrophobicContact CB-CE2 4.1Å; L289-F293 WeakPolarHBondContact O-CB 3.31Å; L289-F293 WeakPolarHBondContact O-CD2 3.47Å; L289-F293 PolarHBondContact O-N 2.68Å; F293-Y296 PolarHBondContact O-N 2.98Å; F293-C297 VanDerWaalsContact O-CB 3.31Å; F293-C297 WeakPolarHBondContact O-CB 3.45Å; F293-C297 PolarHBondContact O-N 2.95Å; F293-C297 PolarHBondContact O-SG 2.89Å
294	S	87.1	Confident	87.6	Confident	29 Å²	29	76.9 Å²	76.9	20%	0.203	35%	0.348	C	S	.	.	H	α-helix	trans	-63.8	-45.2	177	74.4	0	0	0	0	111.4	G290 Y291 F292 Y296 C297 V298	G290-S294 WeakPolarHBondContact O-CB 3.45Å; G290-S294 PolarHBondContact O-N 3.04Å; Y291-S294 PolarHBondContact O-N 2.71Å; Y291-S294 PolarHBondContact O-OG 3.44Å; F292-S294 VanDerWaalsContact C-N 3.32Å; F292-S294 PolarHBondContact O-N 3.44Å; S294-Y296 PolarHBondContact O-N 2.71Å; S294-C297 PolarHBondContact O-N 3.48Å; S294-V298 WeakPolarHBondContact O-CG2 3.18Å; S294-V298 PolarHBondContact O-N 2.89Å
295	I	89.3	Confident	87.7	Confident	119 Å²	119	73.4 Å²	73.4	61%	0.61	34%	0.337	S	S	*	.	H	α-helix	trans	-58.9	-48	174.4	-65.1	167.8	0	0	0	110.2	Y291 F292 C297 V298 W299	Y291-I295 WeakPolarHBondContact O-CG1 3.45Å; Y291-I295 PolarHBondContact O-N 3.36Å; Y291-I295 VanDerWaalsContact O-N 3.15Å; F292-I295 PolarHBondContact O-N 3.48Å; I295-C297 VanDerWaalsContact C-N 3.34Å; I295-C297 PolarHBondContact O-N 3.25Å; I295-V298 PolarHBondContact O-N 2.99Å; I295-W299 WeakPolarHBondContact O-CB 3.34Å; I295-W299 PolarHBondContact O-N 2.88Å
296	Y	87.1	Confident	87.6	Confident	117 Å²	117	68.7 Å²	68.7	46%	0.459	32%	0.321	S	S	.	.	H	α-helix	trans	-59.6	-42.4	176.7	173.1	-95.7	0	0	0	112.6	F292 F293 S294 W299 K300	F292-Y296 PolarHBondContact O-N 3.17Å; F293-Y296 PolarHBondContact O-N 2.98Å; S294-Y296 PolarHBondContact O-N 2.71Å; Y296-W299 PolarHBondContact O-N 2.9Å; Y296-K300 HydrophobicContact CE1-CD 4.11Å; Y296-K300 WeakPolarHBondContact O-CB 3.38Å; Y296-K300 PolarHBondContact O-N 3.02Å
297	C	90	Very high	87.6	Confident	11 Å²	11	68.3 Å²	68.3	7%	0.074	32%	0.321	C	S	.	.	H	α-helix	trans	-69.4	-41.7	-178.7	-68	0	0	0	0	111.6	A166 P170 F293 S294 I295 K300 I301	A166-C297 VanDerWaalsContact CA-SG 3.57Å; A166-C297 HydrophobicContact CB-CB 4.13Å; A166-C297 VanDerWaalsContact O-CB 3.24Å; A166-C297 WeakPolarHBondContact O-CB 3.28Å; A166-C297 PolarHBondContact O-SG 3.44Å; P170-C297 HydrophobicContact CG-CB 4.44Å; F293-C297 VanDerWaalsContact O-CB 3.31Å; F293-C297 WeakPolarHBondContact O-CB 3.45Å; F293-C297 PolarHBondContact O-N 2.95Å; F293-C297 PolarHBondContact O-SG 2.89Å; S294-C297 PolarHBondContact O-N 3.48Å; I295-C297 VanDerWaalsContact C-N 3.34Å; I295-C297 PolarHBondContact O-N 3.25Å; C297-K300 PolarHBondContact O-N 3.17Å; C297-I301 VanDerWaalsContact O-CG1 3.3Å; C297-I301 WeakPolarHBondContact O-CG1 3.4Å; C297-I301 PolarHBondContact O-N 3.02Å
298	V	90.9	Very high	87.6	Confident	101 Å²	101	69 Å²	69	61%	0.612	32%	0.324	S	S	*	.	H	α-helix	trans	-60.7	-46.8	172.9	171.5	0	0	0	0	110.3	S294 I295 K300 I301 F302	S294-V298 WeakPolarHBondContact O-CG2 3.18Å; S294-V298 PolarHBondContact O-N 2.89Å; I295-V298 PolarHBondContact O-N 2.99Å; V298-K300 VanDerWaalsContact C-N 3.33Å; V298-K300 PolarHBondContact O-N 3.5Å; V298-I301 PolarHBondContact O-N 2.76Å; V298-F302 WeakPolarHBondContact O-CB 3.3Å; V298-F302 PolarHBondContact O-N 2.9Å
299	W	90	Very high	87.7	Confident	152 Å²	152	66.9 Å²	66.9	58%	0.576	32%	0.323	S	S	*	.	H	α-helix	trans	-58.8	-43.3	175.3	176.3	-99.2	0	0	0	112.4	I295 Y296 F302 M303	I295-W299 WeakPolarHBondContact O-CB 3.34Å; I295-W299 PolarHBondContact O-N 2.88Å; Y296-W299 PolarHBondContact O-N 2.9Å; W299-F302 PolarHBondContact O-N 3.29Å; W299-M303 HydrophobicContact CD2-CE 4.38Å; W299-M303 HydrophobicContact CD2-CG 4.27Å; W299-M303 HydrophobicContact CE3-CE 4.47Å; W299-M303 HydrophobicContact CH2-CE 3.25Å; W299-M303 HydrophobicContact CZ2-CE 3.1Å; W299-M303 HydrophobicContact CZ2-CG 4.26Å; W299-M303 HydrophobicContact CZ2-SD 4.47Å; W299-M303 HydrophobicContact CZ3-CE 3.96Å; W299-M303 WeakPolarHBondContact O-CB 3.37Å; W299-M303 WeakPolarHBondContact O-CG 3.4Å; W299-M303 PolarHBondContact O-N 3.42Å
300	K	87.1	Confident	87.7	Confident	54 Å²	54	72.4 Å²	72.4	24%	0.235	35%	0.346	C	S	.	.	H	α-helix	trans	-65.9	-42.6	178.8	-171.4	176.2	179	175.7	0	112.1	Y296 C297 V298 F302 M303 A304 F430	Y296-K300 HydrophobicContact CE1-CD 4.11Å; Y296-K300 WeakPolarHBondContact O-CB 3.38Å; Y296-K300 PolarHBondContact O-N 3.02Å; C297-K300 PolarHBondContact O-N 3.17Å; V298-K300 VanDerWaalsContact C-N 3.33Å; V298-K300 PolarHBondContact O-N 3.5Å; K300-F302 VanDerWaalsContact C-N 3.33Å; K300-M303 PolarHBondContact O-N 3.47Å; K300-A304 VanDerWaalsContact O-CB 3.3Å; K300-A304 WeakPolarHBondContact O-CB 3.36Å; K300-A304 PolarHBondContact O-N 3.05Å; K300-F430 HydrophobicContact CB-CZ 4.42Å; K300-F430 HydrophobicContact CD-CE1 4.28Å; K300-F430 HydrophobicContact CD-CE2 4.05Å; K300-F430 HydrophobicContact CD-CZ 3.66Å; K300-F430 HydrophobicContact CG-CE1 3.96Å; K300-F430 HydrophobicContact CG-CZ 3.8Å
301	I	90.1	Very high	87.4	Confident	31 Å²	31	76.7 Å²	76.7	16%	0.159	37%	0.369	C	S	.	.	H	α-helix	trans	-61.4	-44.5	174.6	-69.9	169.3	0	0	0	110.3	C297 V298 T305 F430 L431 A434 I438	C297-I301 VanDerWaalsContact O-CG1 3.3Å; C297-I301 WeakPolarHBondContact O-CG1 3.4Å; C297-I301 PolarHBondContact O-N 3.02Å; V298-I301 PolarHBondContact O-N 2.76Å; I301-T305 WeakPolarHBondContact O-CB 3.46Å; I301-T305 PolarHBondContact O-N 2.99Å; I301-T305 PolarHBondContact O-OG1 3.44Å; I301-F430 HydrophobicContact CG1-CE1 4Å; I301-F430 HydrophobicContact CG1-CZ 4.29Å; I301-L431 HydrophobicContact CG2-CD1 3.84Å; I301-A434 HydrophobicContact CD1-CB 3.99Å; I301-A434 HydrophobicContact CG1-CB 4.15Å; I301-I438 HydrophobicContact CD1-CD1 4.32Å
302	F	90.9	Very high	86.6	Confident	113 Å²	113	78.4 Å²	78.4	50%	0.496	37%	0.374	S	S	.	.	H	α-helix	trans	-61.5	-47.8	176.6	179.6	-107.3	0	0	0	111.9	V298 W299 K300 T305 I306	V298-F302 WeakPolarHBondContact O-CB 3.3Å; V298-F302 PolarHBondContact O-N 2.9Å; W299-F302 PolarHBondContact O-N 3.29Å; K300-F302 VanDerWaalsContact C-N 3.33Å; F302-T305 WeakPolarHBondContact O-CB 3.24Å; F302-T305 PolarHBondContact O-N 2.77Å; F302-I306 HydrophobicContact CD1-CD1 3.83Å; F302-I306 HydrophobicContact CE1-CD1 3.28Å; F302-I306 HydrophobicContact CE1-CG1 4.37Å; F302-I306 HydrophobicContact CE2-CD1 4.21Å; F302-I306 HydrophobicContact CZ-CD1 3.51Å; F302-I306 HydrophobicContact CZ-CG1 4.35Å; F302-I306 PolarHBondContact O-N 2.99Å
303	M	86	Confident	85.4	Confident	56 Å²	56	74.6 Å²	74.6	28%	0.276	36%	0.362	S	S	.	.	H	α-helix	trans	-65.7	-41.4	178.5	-77.7	-62.8	173.8	0	0	112.9	W299 K300 T305 I306 N307	W299-M303 HydrophobicContact CD2-CE 4.38Å; W299-M303 HydrophobicContact CD2-CG 4.27Å; W299-M303 HydrophobicContact CE3-CE 4.47Å; W299-M303 HydrophobicContact CH2-CE 3.25Å; W299-M303 HydrophobicContact CZ2-CE 3.1Å; W299-M303 HydrophobicContact CZ2-CG 4.26Å; W299-M303 HydrophobicContact CZ2-SD 4.47Å; W299-M303 HydrophobicContact CZ3-CE 3.96Å; W299-M303 WeakPolarHBondContact O-CB 3.37Å; W299-M303 WeakPolarHBondContact O-CG 3.4Å; W299-M303 PolarHBondContact O-N 3.42Å; K300-M303 PolarHBondContact O-N 3.47Å; M303-T305 VanDerWaalsContact C-N 3.26Å; M303-T305 PolarHBondContact O-N 2.82Å; M303-I306 PolarHBondContact O-N 3.34Å; M303-I306 HydrophobicContact SD-CD1 4.34Å; M303-N307 WeakPolarHBondContact O-CB 3.4Å; M303-N307 PolarHBondContact O-N 3.26Å; M303-N307 PolarHBondContact O-OD1 3.21Å
304	A	87	Confident	84.1	Confident	3 Å²	3	73.7 Å²	73.7	3%	0.025	37%	0.374	C	S	.	.	H	α-helix	trans	-59.2	-40.6	172.8	0	0	0	0	0	111	K300 N307 I308 D427 F430	K300-A304 VanDerWaalsContact O-CB 3.3Å; K300-A304 WeakPolarHBondContact O-CB 3.36Å; K300-A304 PolarHBondContact O-N 3.05Å; A304-N307 PolarHBondContact O-N 3.28Å; A304-I308 WeakPolarHBondContact O-CD1 3.35Å; A304-I308 WeakPolarHBondContact O-CG1 3.46Å; A304-I308 PolarHBondContact O-N 2.84Å; A304-D427 HydrophobicContact CB-CB 4.18Å; A304-F430 HydrophobicContact CB-CD1 4.03Å; A304-F430 HydrophobicContact CB-CE1 4.34Å
305	T	90.6	Very high	82.5	Confident	53 Å²	53	82.2 Å²	82.2	33%	0.325	41%	0.407	S	S	.	.	H	α-helix	trans	-62.5	-46	175.7	-54.3	0	0	0	0	111.4	I301 F302 M303 I308 V309	I301-T305 WeakPolarHBondContact O-CB 3.46Å; I301-T305 PolarHBondContact O-N 2.99Å; I301-T305 PolarHBondContact O-OG1 3.44Å; F302-T305 WeakPolarHBondContact O-CB 3.24Å; F302-T305 PolarHBondContact O-N 2.77Å; M303-T305 VanDerWaalsContact C-N 3.26Å; M303-T305 PolarHBondContact O-N 2.82Å; T305-I308 PolarHBondContact O-N 3.07Å; T305-V309 HydrophobicContact CG2-CG2 4.34Å; T305-V309 WeakPolarHBondContact O-CB 3.23Å; T305-V309 VanDerWaalsContact O-CG2 3.27Å; T305-V309 WeakPolarHBondContact O-CG2 3.43Å; T305-V309 PolarHBondContact O-N 2.94Å
306	I	88	Confident	80.8	Confident	38 Å²	38	78.9 Å²	78.9	20%	0.195	39%	0.392	C	S	.	.	H	α-helix	trans	-60.3	-46.9	175.3	-72.9	176.4	0	0	0	111.2	F302 M303 I308 V309 F310	F302-I306 HydrophobicContact CD1-CD1 3.83Å; F302-I306 HydrophobicContact CE1-CD1 3.28Å; F302-I306 HydrophobicContact CE1-CG1 4.37Å; F302-I306 HydrophobicContact CE2-CD1 4.21Å; F302-I306 HydrophobicContact CZ-CD1 3.51Å; F302-I306 HydrophobicContact CZ-CG1 4.35Å; F302-I306 PolarHBondContact O-N 2.99Å; M303-I306 PolarHBondContact O-N 3.34Å; M303-I306 HydrophobicContact SD-CD1 4.34Å; I306-I308 VanDerWaalsContact C-N 3.27Å; I306-I308 PolarHBondContact O-N 2.84Å; I306-V309 PolarHBondContact O-N 3.32Å; I306-F310 HydrophobicContact CB-CD2 4.41Å; I306-F310 HydrophobicContact CG2-CD2 3.85Å; I306-F310 HydrophobicContact CG2-CE2 4.49Å; I306-F310 WeakPolarHBondContact O-CB 3.43Å; I306-F310 WeakPolarHBondContact O-CD2 3.36Å; I306-F310 PolarHBondContact O-N 3.18Å
307	N	85.2	Confident	79.3	Confident	43 Å²	43	75.2 Å²	75.2	23%	0.23	38%	0.381	C	S	.	.	H	α-helix	trans	-59.3	-40.7	-179.4	-70	-11	0	0	0	111.5	M303 A304 D311 R312 D427	M303-N307 WeakPolarHBondContact O-CB 3.4Å; M303-N307 PolarHBondContact O-N 3.26Å; M303-N307 PolarHBondContact O-OD1 3.21Å; A304-N307 PolarHBondContact O-N 3.28Å; N307-D311 CarbonylContact O-C 3.59Å; N307-D311 VanDerWaalsContact O-CA 3.28Å; N307-D311 WeakPolarHBondContact O-CA 3.29Å; N307-D311 PolarHBondContact O-N 3.07Å; N307-R312 PolarHBondContact O-N 3.43Å; N307-D427 WeakPolarHBondContact CB-OD2 3.01Å; N307-D427 PolarHBondContact ND2-OD2 3.48Å
308	I	86.8	Confident	77.8	Confident	43 Å²	43	80.1 Å²	80.1	22%	0.221	41%	0.412	C	S	.	.	H	α-helix	trans	-69	-47.9	177.5	-65.4	162	0	0	0	111.4	A304 T305 I306 D427 V428 L431	A304-I308 WeakPolarHBondContact O-CD1 3.35Å; A304-I308 WeakPolarHBondContact O-CG1 3.46Å; A304-I308 PolarHBondContact O-N 2.84Å; T305-I308 PolarHBondContact O-N 3.07Å; I306-I308 VanDerWaalsContact C-N 3.27Å; I306-I308 PolarHBondContact O-N 2.84Å; I308-D427 HydrophobicContact CD1-CB 4.27Å; I308-D427 HydrophobicContact CG1-CB 4.13Å; I308-V428 HydrophobicContact CD1-CB 4.47Å; I308-V428 HydrophobicContact CD1-CG2 3.93Å; I308-V428 HydrophobicContact CG1-CG2 3.89Å; I308-V428 HydrophobicContact CG2-CG2 4.4Å; I308-L431 HydrophobicContact CD1-CB 4.25Å; I308-L431 HydrophobicContact CD1-CD2 3.77Å
309	V	89.3	Confident	76.2	Confident	101 Å²	101	78 Å²	78	61%	0.612	40%	0.4	S	S	*	.	H	α-helix	trans	-69.3	-43.5	-174.5	170.4	0	0	0	0	111.9	T305 I306	T305-V309 HydrophobicContact CG2-CG2 4.34Å; T305-V309 WeakPolarHBondContact O-CB 3.23Å; T305-V309 VanDerWaalsContact O-CG2 3.27Å; T305-V309 WeakPolarHBondContact O-CG2 3.43Å; T305-V309 PolarHBondContact O-N 2.94Å; I306-V309 PolarHBondContact O-N 3.32Å
310	F	84	Confident	74.8	Confident	152 Å²	152	72.9 Å²	72.9	67%	0.667	39%	0.385	S	S	*	.	T	Hydrogen-bonded Turn	trans	-94.7	7	-176.4	-66.8	-77.4	0	0	0	113.5	I306 R312	I306-F310 HydrophobicContact CB-CD2 4.41Å; I306-F310 HydrophobicContact CG2-CD2 3.85Å; I306-F310 HydrophobicContact CG2-CE2 4.49Å; I306-F310 WeakPolarHBondContact O-CB 3.43Å; I306-F310 WeakPolarHBondContact O-CD2 3.36Å; I306-F310 PolarHBondContact O-N 3.18Å; F310-R312 HydrophobicContact CB-CB 4.37Å; F310-R312 PolarHBondContact O-N 2.83Å
311	D	77.4	Confident	73.7	Confident	89 Å²	89	76 Å²	76	48%	0.476	40%	0.395	S	S	.	.	T	Hydrogen-bonded Turn	trans	45	36.9	-171.9	-154	16.8	0	0	0	112.3	N307 V313 R424	N307-D311 CarbonylContact O-C 3.59Å; N307-D311 VanDerWaalsContact O-CA 3.28Å; N307-D311 WeakPolarHBondContact O-CA 3.29Å; N307-D311 PolarHBondContact O-N 3.07Å; D311-V313 PolarHBondContact O-N 3.42Å; D311-R424 IonicContact OD1-CZ 3.36Å; D311-R424 IonicContact OD1-NE 3.29Å; D311-R424 IonicContact OD1-NH1 3.44Å; D311-R424 PolarHBondContact OD1-NH1 2.91Å; D311-R424 IonicContact OD2-NH1 2.7Å; D311-R424 PolarHBondContact OD2-NH1 3.31Å
312	R	70.8	Confident	72.7	Confident	137 Å²	137	75.9 Å²	75.9	52%	0.517	40%	0.402	S	S	.	.			trans	-82	89	-174	-171.9	178.6	177	175.8	-2.9	108.4	N307 F310 G314	N307-R312 PolarHBondContact O-N 3.43Å; F310-R312 HydrophobicContact CB-CB 4.37Å; F310-R312 PolarHBondContact O-N 2.83Å; R312-G314 PolarHBondContact O-N 3.41Å
313	V	62	Low	71.5	Confident	49 Å²	49	72.4 Å²	72.4	30%	0.297	39%	0.388	S	S	.	.			trans	-69	121.6	169.6	-171.8	0	0	0	0	108.2	D311 K315 N420	D311-V313 PolarHBondContact O-N 3.42Å; V313-K315 PolarHBondContact O-N 3.11Å; V313-N420 HydrophobicContact CG1-CB 3.81Å; V313-N420 VanDerWaalsContact CG1-CG 3.48Å; V313-N420 WeakPolarHBondContact CG1-OD1 3.3Å; V313-N420 HydrophobicContact CG2-CB 4.19Å
314	G	57.2	Low	70.7	Confident	57 Å²	57	73.8 Å²	73.8	59%	0.588	39%	0.394	S	S	*	.			trans	-55	97.8	-179.9	0	0	0	0	0	111.6	R312 T316	R312-G314 PolarHBondContact O-N 3.41Å; G314-T316 VanDerWaalsContact C-N 3.27Å; G314-T316 PolarHBondContact O-N 3.01Å
315	K	53.8	Low	70	Confident	208 Å²	208	78.7 Å²	78.7	90%	0.904	42%	0.419	S	S	*	.	S	Bend	trans	-72	-24.4	179.4	-67.3	-170.7	179.3	-178.7	0	112.4	V313	V313-K315 PolarHBondContact O-N 3.11Å
316	T	53.1	Low	69.1	Low	48 Å²	48	79.8 Å²	79.8	29%	0.294	43%	0.426	S	S	.	.	S	Bend	trans	-135.4	131.2	175.9	52.8	0	0	0	0	109.2	G314	G314-T316 VanDerWaalsContact C-N 3.27Å; G314-T316 PolarHBondContact O-N 3.01Å
317	D	55.5	Low	68.3	Low	41 Å²	41	79.6 Å²	79.6	22%	0.219	43%	0.426	C	S	.	.			trans	-61.3	145.4	175.6	53.5	-61.5	0	0	0	110.2	V319 T320 R321	D317-V319 PolarHBondContact O-N 3.16Å; D317-T320 PolarHBondContact O-N 3.01Å; D317-T320 WeakPolarHBondContact OD1-CB 3.41Å; D317-T320 PolarHBondContact OD1-OG1 2.84Å; D317-T320 WeakPolarHBondContact OD2-CB 3.49Å; D317-T320 PolarHBondContact OD2-N 2.97Å; D317-T320 PolarHBondContact OD2-OG1 3.49Å; D317-R321 WeakPolarHBondContact O-CB 3.33Å; D317-R321 PolarHBondContact O-N 3.44Å
318	P	57.8	Low	67.6	Low	113 Å²	113	84 Å²	84	73%	0.734	45%	0.449	S	S	*	.	H	α-helix	trans	-56.4	-29.5	-176.5	-24.6	32.8	0	0	0	113.2	G322	P318-G322 PolarHBondContact O-N 2.87Å
319	V	57.3	Low	67.2	Low	57 Å²	57	91.7 Å²	91.7	35%	0.345	48%	0.477	S	S	.	.	H	α-helix	trans	-77.1	-48.2	-179.8	179.7	0	0	0	0	111	D317 R321 G322 I323 I343 L347	D317-V319 PolarHBondContact O-N 3.16Å; V319-R321 VanDerWaalsContact C-N 3.32Å; V319-R321 PolarHBondContact O-N 3.5Å; V319-G322 CarbonylContact O-C 3.55Å; V319-G322 WeakPolarHBondContact O-CA 3.47Å; V319-G322 PolarHBondContact O-N 3.35Å; V319-G322 VanDerWaalsContact O-N 3.12Å; V319-I323 HydrophobicContact CG1-CD1 3.99Å; V319-I323 VanDerWaalsContact O-CG1 3.26Å; V319-I323 WeakPolarHBondContact O-CG1 3.47Å; V319-I323 PolarHBondContact O-N 3.27Å; V319-I343 HydrophobicContact CG1-CG2 4.03Å; V319-L347 HydrophobicContact CB-CD1 4Å; V319-L347 HydrophobicContact CG1-CD1 4.01Å; V319-L347 HydrophobicContact CG2-CD1 3.44Å; V319-L347 VanDerWaalsContact CG2-CD1 3.44Å
320	T	61.5	Low	66.3	Low	45 Å²	45	91.8 Å²	91.8	28%	0.276	47%	0.474	S	S	.	.	H	α-helix	trans	-61.1	-42.3	172.8	-62.4	0	0	0	0	111.3	D317 G322 I323 E324	D317-T320 PolarHBondContact O-N 3.01Å; D317-T320 WeakPolarHBondContact OD1-CB 3.41Å; D317-T320 PolarHBondContact OD1-OG1 2.84Å; D317-T320 WeakPolarHBondContact OD2-CB 3.49Å; D317-T320 PolarHBondContact OD2-N 2.97Å; D317-T320 PolarHBondContact OD2-OG1 3.49Å; T320-G322 VanDerWaalsContact C-N 3.29Å; T320-G322 PolarHBondContact O-N 3.5Å; T320-I323 CarbonylContact O-C 3.55Å; T320-I323 PolarHBondContact O-N 2.91Å; T320-E324 HydrophobicContact CG2-CG 4.31Å; T320-E324 WeakPolarHBondContact O-CB 3.44Å; T320-E324 VanDerWaalsContact O-CG 3.3Å; T320-E324 WeakPolarHBondContact O-CG 3.44Å; T320-E324 PolarHBondContact O-N 2.8Å
321	R	64.5	Low	65.5	Low	118 Å²	118	87.7 Å²	87.7	45%	0.445	47%	0.474	S	S	.	.	H	α-helix	trans	-63.8	-37.3	175	-163.1	175	-178.4	116.7	2.9	111.9	D317 V319 I325	D317-R321 WeakPolarHBondContact O-CB 3.33Å; D317-R321 PolarHBondContact O-N 3.44Å; V319-R321 VanDerWaalsContact C-N 3.32Å; V319-R321 PolarHBondContact O-N 3.5Å; R321-I325 HydrophobicContact CG-CD1 4.24Å; R321-I325 WeakPolarHBondContact O-CB 3.4Å; R321-I325 WeakPolarHBondContact O-CD1 3.06Å; R321-I325 WeakPolarHBondContact O-CG1 3.49Å; R321-I325 PolarHBondContact O-N 3.45Å
322	G	68.8	Low	64.9	Low	29 Å²	29	87.8 Å²	87.8	30%	0.299	47%	0.474	S	S	.	.	H	α-helix	trans	-63.3	-43.6	172.8	0	0	0	0	0	112.2	P318 V319 T320 I325 T326	P318-G322 PolarHBondContact O-N 2.87Å; V319-G322 CarbonylContact O-C 3.55Å; V319-G322 WeakPolarHBondContact O-CA 3.47Å; V319-G322 PolarHBondContact O-N 3.35Å; V319-G322 VanDerWaalsContact O-N 3.12Å; T320-G322 VanDerWaalsContact C-N 3.29Å; T320-G322 PolarHBondContact O-N 3.5Å; G322-I325 PolarHBondContact O-N 3.37Å; G322-T326 VanDerWaalsContact O-CB 3.28Å; G322-T326 WeakPolarHBondContact O-CB 3.39Å; G322-T326 PolarHBondContact O-N 2.97Å; G322-T326 PolarHBondContact O-OG1 2.88Å
323	I	65.8	Low	64.7	Low	40 Å²	40	90.7 Å²	90.7	21%	0.205	49%	0.493	C	S	.	.	H	α-helix	trans	-64.1	-47.4	175.1	-66.7	164.2	0	0	0	110.1	V319 T320 I325 T326 V327 I343	V319-I323 HydrophobicContact CG1-CD1 3.99Å; V319-I323 VanDerWaalsContact O-CG1 3.26Å; V319-I323 WeakPolarHBondContact O-CG1 3.47Å; V319-I323 PolarHBondContact O-N 3.27Å; T320-I323 CarbonylContact O-C 3.55Å; T320-I323 PolarHBondContact O-N 2.91Å; I323-I325 VanDerWaalsContact C-N 3.35Å; I323-I325 PolarHBondContact O-N 3.3Å; I323-T326 CarbonylContact O-C 3.59Å; I323-T326 PolarHBondContact O-N 3.13Å; I323-T326 VanDerWaalsContact O-N 3.11Å; I323-V327 HydrophobicContact CG2-CG2 3.98Å; I323-V327 WeakPolarHBondContact O-CB 3.45Å; I323-V327 VanDerWaalsContact O-CG2 3.24Å; I323-V327 WeakPolarHBondContact O-CG2 3.39Å; I323-V327 PolarHBondContact O-N 3.41Å; I323-I343 HydrophobicContact CD1-CD1 3.83Å; I323-I343 HydrophobicContact CD1-CG2 4.22Å; I323-I343 HydrophobicContact CG1-CD1 4.41Å
324	E	68.3	Low	64.8	Low	86 Å²	86	91.7 Å²	91.7	40%	0.402	49%	0.494	S	S	.	.	H	α-helix	trans	-56.8	-46.5	177.1	-76.1	172.4	-179	0	0	111.6	T320 T326 N328	T320-E324 HydrophobicContact CG2-CG 4.31Å; T320-E324 WeakPolarHBondContact O-CB 3.44Å; T320-E324 VanDerWaalsContact O-CG 3.3Å; T320-E324 WeakPolarHBondContact O-CG 3.44Å; T320-E324 PolarHBondContact O-N 2.8Å; E324-T326 VanDerWaalsContact C-N 3.34Å; E324-N328 WeakPolarHBondContact O-CB 3.39Å; E324-N328 PolarHBondContact O-N 2.92Å; E324-N328 PolarHBondContact O-ND2 3.08Å; E324-N328 VanDerWaalsContact O-ND2 3.13Å
325	I	72.4	Confident	65.5	Low	106 Å²	106	93.6 Å²	93.6	54%	0.544	49%	0.49	S	S	.	.	H	α-helix	trans	-63.3	-43.4	176.4	-68.4	164.2	0	0	0	110.3	R321 G322 I323 N328 Y329	R321-I325 HydrophobicContact CG-CD1 4.24Å; R321-I325 WeakPolarHBondContact O-CB 3.4Å; R321-I325 WeakPolarHBondContact O-CD1 3.06Å; R321-I325 WeakPolarHBondContact O-CG1 3.49Å; R321-I325 PolarHBondContact O-N 3.45Å; G322-I325 PolarHBondContact O-N 3.37Å; I323-I325 VanDerWaalsContact C-N 3.35Å; I323-I325 PolarHBondContact O-N 3.3Å; I325-N328 PolarHBondContact O-N 3.32Å; I325-Y329 WeakPolarHBondContact O-CB 3.1Å; I325-Y329 PolarHBondContact O-N 3.46Å
326	T	71.6	Confident	66.3	Low	76 Å²	76	87.4 Å²	87.4	47%	0.466	47%	0.47	S	S	.	.	H	α-helix	trans	-65.4	-44.7	-178.9	-58	0	0	0	0	111.4	G322 I323 E324 Y329 L330	G322-T326 VanDerWaalsContact O-CB 3.28Å; G322-T326 WeakPolarHBondContact O-CB 3.39Å; G322-T326 PolarHBondContact O-N 2.97Å; G322-T326 PolarHBondContact O-OG1 2.88Å; I323-T326 CarbonylContact O-C 3.59Å; I323-T326 PolarHBondContact O-N 3.13Å; I323-T326 VanDerWaalsContact O-N 3.11Å; E324-T326 VanDerWaalsContact C-N 3.34Å; T326-Y329 PolarHBondContact O-N 2.85Å; T326-L330 HydrophobicContact CG2-CD1 3.53Å; T326-L330 VanDerWaalsContact O-CB 3.3Å; T326-L330 WeakPolarHBondContact O-CB 3.23Å; T326-L330 PolarHBondContact O-N 3.37Å
327	V	70.8	Confident	67.1	Low	34 Å²	34	91.7 Å²	91.7	21%	0.206	49%	0.485	C	S	.	.	H	α-helix	trans	-65	-46.2	177.4	171.7	0	0	0	0	110.6	I323 Y329 G331 F334	I323-V327 HydrophobicContact CG2-CG2 3.98Å; I323-V327 WeakPolarHBondContact O-CB 3.45Å; I323-V327 VanDerWaalsContact O-CG2 3.24Å; I323-V327 WeakPolarHBondContact O-CG2 3.39Å; I323-V327 PolarHBondContact O-N 3.41Å; V327-Y329 PolarHBondContact O-N 3.22Å; V327-G331 PolarHBondContact O-N 3.37Å; V327-G331 VanDerWaalsContact O-N 3.12Å; V327-F334 HydrophobicContact CG2-CB 4.02Å; V327-F334 HydrophobicContact CG2-CD1 4.39Å; V327-F334 HydrophobicContact CG2-CG 4.44Å
328	N	71.9	Confident	68.1	Low	135 Å²	135	94.6 Å²	94.6	72%	0.722	50%	0.495	S	S	*	.	H	α-helix	trans	-67.8	-34.6	179.2	-70.7	-23.8	0	0	0	112.6	E324 I325	E324-N328 WeakPolarHBondContact O-CB 3.39Å; E324-N328 PolarHBondContact O-N 2.92Å; E324-N328 PolarHBondContact O-ND2 3.08Å; E324-N328 VanDerWaalsContact O-ND2 3.13Å; I325-N328 PolarHBondContact O-N 3.32Å
329	Y	77.2	Confident	69.1	Low	205 Å²	205	94.8 Å²	94.8	80%	0.804	48%	0.481	S	S	*	.	H	α-helix	trans	-80	-38.4	-178.7	-171.3	-100.3	0	0	0	112.9	I325 T326 V327	I325-Y329 WeakPolarHBondContact O-CB 3.1Å; I325-Y329 PolarHBondContact O-N 3.46Å; T326-Y329 PolarHBondContact O-N 2.85Å; V327-Y329 PolarHBondContact O-N 3.22Å
330	L	71.5	Confident	69.8	Low	103 Å²	103	93.1 Å²	93.1	54%	0.539	47%	0.473	S	S	.	.	H	α-helix	trans	-87.2	-11.6	-177.5	-72	159.4	0	0	0	113.5	T326 I332	T326-L330 HydrophobicContact CG2-CD1 3.53Å; T326-L330 VanDerWaalsContact O-CB 3.3Å; T326-L330 WeakPolarHBondContact O-CB 3.23Å; T326-L330 PolarHBondContact O-N 3.37Å; L330-I332 HydrophobicContact CB-CD1 3.74Å; L330-I332 HydrophobicContact CB-CG1 3.89Å; L330-I332 HydrophobicContact CD1-CD1 4.26Å; L330-I332 HydrophobicContact CG-CD1 4.45Å; L330-I332 PolarHBondContact O-N 2.75Å
331	G	66.4	Low	70.6	Confident	66 Å²	66	93.9 Å²	93.9	68%	0.68	47%	0.473	S	S	*	.			trans	60.8	15.6	178.7	0	0	0	0	0	114.1	V327	V327-G331 PolarHBondContact O-N 3.37Å; V327-G331 VanDerWaalsContact O-N 3.12Å
332	I	65.2	Low	71.5	Confident	91 Å²	91	91.9 Å²	91.9	47%	0.467	47%	0.468	S	S	.	.			trans	-76.9	129.1	-179.3	-61.9	167.6	0	0	0	107.3	L330 F334	L330-I332 HydrophobicContact CB-CD1 3.74Å; L330-I332 HydrophobicContact CB-CG1 3.89Å; L330-I332 HydrophobicContact CD1-CD1 4.26Å; L330-I332 HydrophobicContact CG-CD1 4.45Å; L330-I332 PolarHBondContact O-N 2.75Å; I332-F334 HydrophobicContact CG2-CB 4.45Å; I332-F334 HydrophobicContact CG2-CD2 4.2Å; I332-F334 PolarHBondContact O-N 3.46Å
333	Q	65.5	Low	72.1	Confident	198 Å²	198	92.9 Å²	92.9	93%	0.925	47%	0.466	S	S	*	.			trans	-66.4	75.9	165.4	-68.6	-170.4	-5.4	0	0	108.9
334	F	64.3	Low	72.5	Confident	70 Å²	70	91.5 Å²	91.5	31%	0.307	46%	0.461	S	S	.	.			trans	-81.3	124.6	179.8	-152	-111.3	0	0	0	107.3	V327 I332 V336 W339	V327-F334 HydrophobicContact CG2-CB 4.02Å; V327-F334 HydrophobicContact CG2-CD1 4.39Å; V327-F334 HydrophobicContact CG2-CG 4.44Å; I332-F334 HydrophobicContact CG2-CB 4.45Å; I332-F334 HydrophobicContact CG2-CD2 4.2Å; I332-F334 PolarHBondContact O-N 3.46Å; F334-V336 WeakPolarHBondContact O-CG2 3.33Å; F334-V336 PolarHBondContact O-N 3.48Å; F334-W339 HydrophobicContact CD1-CB 3.96Å; F334-W339 AromaticContact CD1-CD1 3.8Å; F334-W339 HydrophobicContact CD1-CG 4Å; F334-W339 HydrophobicContact CE1-CB 3.19Å; F334-W339 AromaticContact CE1-CD1 3.35Å; F334-W339 AromaticContact CE1-CD2 3.9Å; F334-W339 HydrophobicContact CE1-CD2 3.9Å; F334-W339 AromaticContact CE1-CG 3.17Å; F334-W339 HydrophobicContact CE1-CG 3.17Å; F334-W339 AromaticContact CE2-CD1 3.76Å; F334-W339 HydrophobicContact CE2-CD2 4.27Å; F334-W339 HydrophobicContact CE2-CG 4.12Å; F334-W339 AromaticContact CE2-NE1 3.68Å; F334-W339 HydrophobicContact CZ-CB 3.78Å; F334-W339 AromaticContact CZ-CD1 3.31Å; F334-W339 AromaticContact CZ-CD2 3.46Å; F334-W339 HydrophobicContact CZ-CD2 3.46Å; F334-W339 VanDerWaalsContact CZ-CD2 3.46Å; F334-W339 AromaticContact CZ-CE2 3.67Å; F334-W339 HydrophobicContact CZ-CE3 4.19Å; F334-W339 AromaticContact CZ-CG 3.23Å; F334-W339 HydrophobicContact CZ-CG 3.23Å; F334-W339 AromaticContact CZ-NE1 3.56Å
335	D	73.2	Confident	73.3	Confident	96 Å²	96	91 Å²	91	51%	0.513	46%	0.457	S	S	.	.			trans	-68.3	88.5	169.7	-174.2	-7.5	0	0	0	108.3	K337 F338 W339	D335-K337 PolarHBondContact O-N 2.94Å; D335-K337 PolarHBondContact OD1-N 3.24Å; D335-K337 VanDerWaalsContact OD1-N 3.15Å; D335-F338 HydrophobicContact CB-CB 4.09Å; D335-F338 PolarHBondContact O-N 3.28Å; D335-F338 PolarHBondContact OD1-N 3.33Å; D335-F338 WeakPolarHBondContact OD2-CB 3.42Å; D335-W339 PolarHBondContact O-N 3.5Å; D335-W339 VanDerWaalsContact O-N 3.08Å
336	V	69	Low	73.9	Confident	79 Å²	79	90.7 Å²	90.7	48%	0.479	46%	0.456	S	S	.	.	H	α-helix	trans	-55.6	-34.4	-177.3	-177.9	0	0	0	0	110	F334 S340	F334-V336 WeakPolarHBondContact O-CG2 3.33Å; F334-V336 PolarHBondContact O-N 3.48Å; V336-S340 WeakPolarHBondContact O-CA 3.5Å; V336-S340 WeakPolarHBondContact O-CB 3.32Å; V336-S340 PolarHBondContact O-N 3.38Å; V336-S340 PolarHBondContact O-OG 2.85Å
337	K	70.3	Confident	74.4	Confident	138 Å²	138	89 Å²	89	60%	0.6	44%	0.444	S	S	*	.	H	α-helix	trans	-70.5	-51.6	-178.5	-68.9	-174.2	174.8	-175.8	0	111.3	D335 W339 S340 Q341	D335-K337 PolarHBondContact O-N 2.94Å; D335-K337 PolarHBondContact OD1-N 3.24Å; D335-K337 VanDerWaalsContact OD1-N 3.15Å; K337-W339 PolarHBondContact O-N 3.18Å; K337-S340 PolarHBondContact O-N 3.12Å; K337-S340 PolarHBondContact O-OG 2.91Å; K337-Q341 PolarHBondContact O-N 2.9Å
338	F	76.5	Confident	74.9	Confident	101 Å²	101	87.5 Å²	87.5	44%	0.443	43%	0.434	S	S	.	.	H	α-helix	trans	-58.5	-50.6	178.7	178.8	-98.6	0	0	0	112.1	D335 H342	D335-F338 HydrophobicContact CB-CB 4.09Å; D335-F338 PolarHBondContact O-N 3.28Å; D335-F338 PolarHBondContact OD1-N 3.33Å; D335-F338 WeakPolarHBondContact OD2-CB 3.42Å; F338-H342 AromaticContact CD1-CD2 3.99Å; F338-H342 AromaticContact CE1-CD2 3.59Å; F338-H342 AromaticContact CE1-NE2 3.76Å; F338-H342 AromaticContact CE2-CD2 3.92Å; F338-H342 AromaticContact CE2-NE2 3.33Å; F338-H342 VanDerWaalsContact CE2-NE2 3.33Å; F338-H342 WeakPolarHBondContact CE2-NE2 3.29Å; F338-H342 AromaticContact CZ-CD2 3.56Å; F338-H342 AromaticContact CZ-NE2 3.18Å; F338-H342 WeakPolarHBondContact CZ-NE2 3.4Å; F338-H342 PolarHBondContact O-CD2 3.32Å; F338-H342 VanDerWaalsContact O-CD2 3.25Å
339	W	78.7	Confident	75.5	Confident	117 Å²	117	82 Å²	82	44%	0.443	41%	0.41	S	S	.	.	H	α-helix	trans	-74.6	-31.4	-177	-76.7	101.9	0	0	0	113.5	F334 D335 K337 Q341 H342 I343	F334-W339 HydrophobicContact CD1-CB 3.96Å; F334-W339 AromaticContact CD1-CD1 3.8Å; F334-W339 HydrophobicContact CD1-CG 4Å; F334-W339 HydrophobicContact CE1-CB 3.19Å; F334-W339 AromaticContact CE1-CD1 3.35Å; F334-W339 AromaticContact CE1-CD2 3.9Å; F334-W339 HydrophobicContact CE1-CD2 3.9Å; F334-W339 AromaticContact CE1-CG 3.17Å; F334-W339 HydrophobicContact CE1-CG 3.17Å; F334-W339 AromaticContact CE2-CD1 3.76Å; F334-W339 HydrophobicContact CE2-CD2 4.27Å; F334-W339 HydrophobicContact CE2-CG 4.12Å; F334-W339 AromaticContact CE2-NE1 3.68Å; F334-W339 HydrophobicContact CZ-CB 3.78Å; F334-W339 AromaticContact CZ-CD1 3.31Å; F334-W339 AromaticContact CZ-CD2 3.46Å; F334-W339 HydrophobicContact CZ-CD2 3.46Å; F334-W339 VanDerWaalsContact CZ-CD2 3.46Å; F334-W339 AromaticContact CZ-CE2 3.67Å; F334-W339 HydrophobicContact CZ-CE3 4.19Å; F334-W339 AromaticContact CZ-CG 3.23Å; F334-W339 HydrophobicContact CZ-CG 3.23Å; F334-W339 AromaticContact CZ-NE1 3.56Å; D335-W339 PolarHBondContact O-N 3.5Å; D335-W339 VanDerWaalsContact O-N 3.08Å; K337-W339 PolarHBondContact O-N 3.18Å; W339-Q341 VanDerWaalsContact C-N 3.27Å; W339-Q341 PolarHBondContact O-N 3.03Å; W339-H342 PolarHBondContact O-N 3.44Å; W339-I343 HydrophobicContact CB-CD1 4.31Å; W339-I343 WeakPolarHBondContact O-CB 3.37Å; W339-I343 WeakPolarHBondContact O-CG1 3.48Å; W339-I343 PolarHBondContact O-N 3.34Å
340	S	71.9	Confident	75.9	Confident	23 Å²	23	77 Å²	77	16%	0.161	40%	0.396	C	S	.	.	H	α-helix	trans	-61.9	-36.7	177.4	65.6	0	0	0	0	111.9	V336 K337 S344	V336-S340 WeakPolarHBondContact O-CA 3.5Å; V336-S340 WeakPolarHBondContact O-CB 3.32Å; V336-S340 PolarHBondContact O-N 3.38Å; V336-S340 PolarHBondContact O-OG 2.85Å; K337-S340 PolarHBondContact O-N 3.12Å; K337-S340 PolarHBondContact O-OG 2.91Å; S340-S344 WeakPolarHBondContact O-CB 3.41Å; S340-S344 PolarHBondContact O-N 3.48Å; S340-S344 PolarHBondContact O-OG 3.49Å
341	Q	79.3	Confident	76.5	Confident	60 Å²	60	74.5 Å²	74.5	28%	0.28	38%	0.382	S	S	.	.	H	α-helix	trans	-63.8	-50.9	176.1	-167.4	-179.9	-0.3	0	0	111.3	I62 K337 W339 S344 F345 Y406	I62-Q341 HydrophobicContact CG2-CG 4.18Å; I62-Q341 PolarHBondContact O-NE2 3.37Å; K337-Q341 PolarHBondContact O-N 2.9Å; W339-Q341 VanDerWaalsContact C-N 3.27Å; W339-Q341 PolarHBondContact O-N 3.03Å; Q341-S344 PolarHBondContact O-N 3.04Å; Q341-F345 WeakPolarHBondContact O-CB 3.33Å; Q341-F345 PolarHBondContact O-N 3.37Å; Q341-Y406 VanDerWaalsContact CB-OH 3.3Å; Q341-Y406 WeakPolarHBondContact CB-OH 3.37Å; Q341-Y406 HydrophobicContact CG-CE1 4.27Å; Q341-Y406 WeakPolarHBondContact CG-OH 3.36Å
342	H	83.8	Confident	77.4	Confident	76 Å²	76	71.8 Å²	71.8	35%	0.352	35%	0.352	S	S	.	.	H	α-helix	trans	-64.8	-43.2	-179.6	-70	-58	0	0	0	112.6	F338 W339 F345 I346	F338-H342 AromaticContact CD1-CD2 3.99Å; F338-H342 AromaticContact CE1-CD2 3.59Å; F338-H342 AromaticContact CE1-NE2 3.76Å; F338-H342 AromaticContact CE2-CD2 3.92Å; F338-H342 AromaticContact CE2-NE2 3.33Å; F338-H342 VanDerWaalsContact CE2-NE2 3.33Å; F338-H342 WeakPolarHBondContact CE2-NE2 3.29Å; F338-H342 AromaticContact CZ-CD2 3.56Å; F338-H342 AromaticContact CZ-NE2 3.18Å; F338-H342 WeakPolarHBondContact CZ-NE2 3.4Å; F338-H342 PolarHBondContact O-CD2 3.32Å; F338-H342 VanDerWaalsContact O-CD2 3.25Å; W339-H342 PolarHBondContact O-N 3.44Å; H342-F345 PolarHBondContact O-N 2.89Å; H342-I346 VanDerWaalsContact O-CG1 3.29Å; H342-I346 WeakPolarHBondContact O-CG1 3.36Å; H342-I346 PolarHBondContact O-N 3.43Å
343	I	79.7	Confident	78.4	Confident	50 Å²	50	72 Å²	72	26%	0.256	36%	0.357	S	S	.	.	H	α-helix	trans	-64.6	-44.1	177.2	-66.8	167.8	0	0	0	110	V319 I323 W339 I346 L347	V319-I343 HydrophobicContact CG1-CG2 4.03Å; I323-I343 HydrophobicContact CD1-CD1 3.83Å; I323-I343 HydrophobicContact CD1-CG2 4.22Å; I323-I343 HydrophobicContact CG1-CD1 4.41Å; W339-I343 HydrophobicContact CB-CD1 4.31Å; W339-I343 WeakPolarHBondContact O-CB 3.37Å; W339-I343 WeakPolarHBondContact O-CG1 3.48Å; W339-I343 PolarHBondContact O-N 3.34Å; I343-I346 PolarHBondContact O-N 3.26Å; I343-L347 WeakPolarHBondContact O-CB 3.48Å; I343-L347 PolarHBondContact O-N 2.81Å
344	S	75.4	Confident	79.3	Confident	12 Å²	12	66.4 Å²	66.4	8%	0.084	34%	0.337	C	S	.	.	H	α-helix	trans	-62.6	-44.3	177.4	-64.6	0	0	0	0	111.2	S340 Q341 L347 V348 P403	S340-S344 WeakPolarHBondContact O-CB 3.41Å; S340-S344 PolarHBondContact O-N 3.48Å; S340-S344 PolarHBondContact O-OG 3.49Å; Q341-S344 PolarHBondContact O-N 3.04Å; S344-L347 PolarHBondContact O-N 3.15Å; S344-V348 WeakPolarHBondContact O-CB 3.4Å; S344-V348 WeakPolarHBondContact O-CG2 3.33Å; S344-V348 PolarHBondContact O-N 3.34Å; S344-P403 WeakPolarHBondContact OG-CD 3.18Å; S344-P403 WeakPolarHBondContact OG-CG 3.31Å
345	F	83.7	Confident	80.2	Confident	74 Å²	74	63.7 Å²	63.7	33%	0.325	33%	0.327	S	S	.	.	H	α-helix	trans	-58.7	-48.9	175.3	174.3	-105.1	0	0	0	112.1	I59 I62 L63 Q341 H342 G349	I59-F345 HydrophobicContact CG2-CD2 4.48Å; I59-F345 HydrophobicContact CG2-CE2 3.83Å; I62-F345 HydrophobicContact CG2-CB 3.91Å; L63-F345 HydrophobicContact CD1-CD2 4.36Å; L63-F345 HydrophobicContact CD1-CE2 3.86Å; L63-F345 HydrophobicContact CD1-CZ 4.49Å; L63-F345 HydrophobicContact CD2-CD2 3.83Å; L63-F345 HydrophobicContact CD2-CE2 4.03Å; L63-F345 HydrophobicContact CD2-CG 4.26Å; L63-F345 HydrophobicContact CG-CD2 4.02Å; L63-F345 HydrophobicContact CG-CE2 4.04Å; Q341-F345 WeakPolarHBondContact O-CB 3.33Å; Q341-F345 PolarHBondContact O-N 3.37Å; H342-F345 PolarHBondContact O-N 2.89Å; F345-G349 PolarHBondContact O-N 2.83Å
346	I	85.9	Confident	80.8	Confident	100 Å²	100	60.6 Å²	60.6	51%	0.513	31%	0.31	S	S	.	.	H	α-helix	trans	-64	-47.9	179.5	-69	167.9	0	0	0	110.5	H342 I343 G349 I350	H342-I346 VanDerWaalsContact O-CG1 3.29Å; H342-I346 WeakPolarHBondContact O-CG1 3.36Å; H342-I346 PolarHBondContact O-N 3.43Å; I343-I346 PolarHBondContact O-N 3.26Å; I346-G349 PolarHBondContact O-N 3.21Å; I346-I350 HydrophobicContact CG2-CD1 3.77Å; I346-I350 HydrophobicContact CG2-CG1 4.49Å; I346-I350 WeakPolarHBondContact O-CB 3.17Å; I346-I350 VanDerWaalsContact O-CG1 3.25Å; I346-I350 WeakPolarHBondContact O-CG1 3.18Å; I346-I350 PolarHBondContact O-N 2.92Å
347	L	81.4	Confident	81.6	Confident	42 Å²	42	65.3 Å²	65.3	22%	0.22	32%	0.319	C	S	.	.	H	α-helix	trans	-63.3	-49.8	-178.2	178.4	142.4	0	0	0	111.4	V319 I343 S344 G349 I350 I351	V319-L347 HydrophobicContact CB-CD1 4Å; V319-L347 HydrophobicContact CG1-CD1 4.01Å; V319-L347 HydrophobicContact CG2-CD1 3.44Å; V319-L347 VanDerWaalsContact CG2-CD1 3.44Å; I343-L347 WeakPolarHBondContact O-CB 3.48Å; I343-L347 PolarHBondContact O-N 2.81Å; S344-L347 PolarHBondContact O-N 3.15Å; L347-G349 VanDerWaalsContact C-N 3.33Å; L347-G349 PolarHBondContact O-N 2.8Å; L347-I350 PolarHBondContact O-N 3.42Å; L347-I351 HydrophobicContact CD2-CD1 3.44Å; L347-I351 VanDerWaalsContact CD2-CD1 3.44Å; L347-I351 HydrophobicContact CD2-CG1 4.44Å; L347-I351 HydrophobicContact CG-CD1 4.09Å; L347-I351 VanDerWaalsContact O-CG1 3.29Å; L347-I351 WeakPolarHBondContact O-CG1 3.3Å; L347-I351 PolarHBondContact O-N 3.04Å
348	V	81.3	Confident	82.2	Confident	1 Å²	1	60.3 Å²	60.3	1%	0.006	31%	0.307	C	S	.	.	H	α-helix	trans	-64	-41.6	178.4	172.4	0	0	0	0	110	I58 I62 S344 I350 I351 I352 I398 M402	I58-V348 HydrophobicContact CG2-CG1 3.72Å; I62-V348 HydrophobicContact CD1-CB 3.98Å; I62-V348 HydrophobicContact CD1-CG1 4.03Å; I62-V348 HydrophobicContact CD1-CG2 4.01Å; S344-V348 WeakPolarHBondContact O-CB 3.4Å; S344-V348 WeakPolarHBondContact O-CG2 3.33Å; S344-V348 PolarHBondContact O-N 3.34Å; V348-I350 PolarHBondContact O-N 3.46Å; V348-I351 PolarHBondContact O-N 3.39Å; V348-I352 HydrophobicContact CG1-CD1 3.56Å; V348-I352 HydrophobicContact CG1-CG1 4.2Å; V348-I352 WeakPolarHBondContact O-CB 3.38Å; V348-I352 WeakPolarHBondContact O-CD1 3.15Å; V348-I352 WeakPolarHBondContact O-CG1 3.36Å; V348-I352 PolarHBondContact O-N 3.45Å; V348-I398 HydrophobicContact CG1-CG2 4.17Å; V348-I398 HydrophobicContact CG2-CG2 4.26Å; V348-M402 HydrophobicContact CG2-CG 3.97Å; V348-M402 HydrophobicContact CG2-SD 4.32Å
349	G	85.4	Confident	82.5	Confident	20 Å²	20	55.7 Å²	55.7	21%	0.206	29%	0.286	C	S	.	.	H	α-helix	trans	-57.9	-46	173.9	0	0	0	0	0	112.8	F345 I346 L347 I352 V353	F345-G349 PolarHBondContact O-N 2.83Å; I346-G349 PolarHBondContact O-N 3.21Å; L347-G349 VanDerWaalsContact C-N 3.33Å; L347-G349 PolarHBondContact O-N 2.8Å; G349-I352 PolarHBondContact O-N 3.04Å; G349-V353 WeakPolarHBondContact O-CG2 3.42Å; G349-V353 PolarHBondContact O-N 2.96Å
350	I	85.8	Confident	82.8	Confident	100 Å²	100	50.9 Å²	50.9	51%	0.513	27%	0.269	S	S	.	.	H	α-helix	trans	-62.3	-45.7	175	-69.8	167.3	0	0	0	110.5	I346 L347 V348 I352 V353 T354	I346-I350 HydrophobicContact CG2-CD1 3.77Å; I346-I350 HydrophobicContact CG2-CG1 4.49Å; I346-I350 WeakPolarHBondContact O-CB 3.17Å; I346-I350 VanDerWaalsContact O-CG1 3.25Å; I346-I350 WeakPolarHBondContact O-CG1 3.18Å; I346-I350 PolarHBondContact O-N 2.92Å; L347-I350 PolarHBondContact O-N 3.42Å; V348-I350 PolarHBondContact O-N 3.46Å; I350-I352 VanDerWaalsContact C-N 3.33Å; I350-I352 PolarHBondContact O-N 3.25Å; I350-V353 PolarHBondContact O-N 3.41Å; I350-T354 HydrophobicContact CG2-CG2 4.1Å; I350-T354 VanDerWaalsContact O-CB 3.3Å; I350-T354 WeakPolarHBondContact O-CB 3.3Å; I350-T354 VanDerWaalsContact O-CG2 3.23Å; I350-T354 WeakPolarHBondContact O-CG2 3.45Å; I350-T354 PolarHBondContact O-N 3.44Å; I350-T354 PolarHBondContact O-OG1 3.34Å
351	I	83.4	Confident	83.4	Confident	50 Å²	50	53.4 Å²	53.4	26%	0.256	28%	0.28	S	S	.	.	H	α-helix	trans	-59.3	-46.1	178	-69.7	171.2	0	0	0	110.1	L347 V348 T354 S355 I398	L347-I351 HydrophobicContact CD2-CD1 3.44Å; L347-I351 VanDerWaalsContact CD2-CD1 3.44Å; L347-I351 HydrophobicContact CD2-CG1 4.44Å; L347-I351 HydrophobicContact CG-CD1 4.09Å; L347-I351 VanDerWaalsContact O-CG1 3.29Å; L347-I351 WeakPolarHBondContact O-CG1 3.3Å; L347-I351 PolarHBondContact O-N 3.04Å; V348-I351 PolarHBondContact O-N 3.39Å; I351-T354 WeakPolarHBondContact CA-OG1 3.36Å; I351-T354 PolarHBondContact O-OG1 2.84Å; I351-T354 VanDerWaalsContact O-OG1 3.04Å; I351-S355 WeakPolarHBondContact O-CB 3.41Å; I351-S355 PolarHBondContact O-N 3.37Å; I351-S355 PolarHBondContact O-OG 2.9Å; I351-I398 HydrophobicContact CG2-CD1 3.97Å; I351-I398 HydrophobicContact CG2-CG1 3.94Å
352	I	84.8	Confident	83.6	Confident	10 Å²	10	53.3 Å²	53.3	5%	0.051	28%	0.284	C	S	.	.	H	α-helix	trans	-61	-53.2	179.7	-69.5	163.6	0	0	0	110.4	F55 I59 V348 G349 I350 T354 S355 I356 I398	F55-I352 HydrophobicContact CB-CD1 3.89Å; F55-I352 HydrophobicContact CB-CG1 4.05Å; F55-I352 HydrophobicContact CB-CG2 3.71Å; F55-I352 HydrophobicContact CD1-CB 4.46Å; F55-I352 HydrophobicContact CD1-CD1 4.11Å; F55-I352 HydrophobicContact CD1-CG1 3.6Å; F55-I352 HydrophobicContact CD1-CG2 4.24Å; F55-I352 HydrophobicContact CD2-CG2 3.86Å; F55-I352 HydrophobicContact CE1-CG1 4.16Å; F55-I352 HydrophobicContact CE2-CG2 4.47Å; F55-I352 HydrophobicContact CG-CB 4.4Å; F55-I352 HydrophobicContact CG-CD1 4.27Å; F55-I352 HydrophobicContact CG-CG1 3.9Å; F55-I352 HydrophobicContact CG-CG2 3.7Å; I59-I352 HydrophobicContact CD1-CD1 4.14Å; I59-I352 HydrophobicContact CG1-CD1 4.13Å; V348-I352 HydrophobicContact CG1-CD1 3.56Å; V348-I352 HydrophobicContact CG1-CG1 4.2Å; V348-I352 WeakPolarHBondContact O-CB 3.38Å; V348-I352 WeakPolarHBondContact O-CD1 3.15Å; V348-I352 WeakPolarHBondContact O-CG1 3.36Å; V348-I352 PolarHBondContact O-N 3.45Å; G349-I352 PolarHBondContact O-N 3.04Å; I350-I352 VanDerWaalsContact C-N 3.33Å; I350-I352 PolarHBondContact O-N 3.25Å; I352-T354 PolarHBondContact O-N 2.92Å; I352-S355 PolarHBondContact O-N 2.84Å; I352-I356 HydrophobicContact CG2-CD1 3.68Å; I352-I356 HydrophobicContact CG2-CG1 4.45Å; I352-I356 WeakPolarHBondContact O-CG1 3.41Å; I352-I356 PolarHBondContact O-N 2.88Å; I352-I398 HydrophobicContact CG1-CD1 4.4Å
353	V	87.2	Confident	83.5	Confident	94 Å²	94	50.1 Å²	50.1	57%	0.57	27%	0.27	S	S	*	.	H	α-helix	trans	-62.8	-43.6	-177.1	171.9	0	0	0	0	111.1	G349 I350 R357	G349-V353 WeakPolarHBondContact O-CG2 3.42Å; G349-V353 PolarHBondContact O-N 2.96Å; I350-V353 PolarHBondContact O-N 3.41Å; V353-R357 WeakPolarHBondContact O-CB 3.09Å; V353-R357 PolarHBondContact O-N 2.83Å
354	T	83.6	Confident	83.7	Confident	82 Å²	82	48.4 Å²	48.4	50%	0.503	26%	0.261	S	S	.	.	H	α-helix	trans	-67.4	-38.1	177.8	54.9	0	0	0	0	112.1	I350 I351 I352 G358	I350-T354 HydrophobicContact CG2-CG2 4.1Å; I350-T354 VanDerWaalsContact O-CB 3.3Å; I350-T354 WeakPolarHBondContact O-CB 3.3Å; I350-T354 VanDerWaalsContact O-CG2 3.23Å; I350-T354 WeakPolarHBondContact O-CG2 3.45Å; I350-T354 PolarHBondContact O-N 3.44Å; I350-T354 PolarHBondContact O-OG1 3.34Å; I351-T354 WeakPolarHBondContact CA-OG1 3.36Å; I351-T354 PolarHBondContact O-OG1 2.84Å; I351-T354 VanDerWaalsContact O-OG1 3.04Å; I352-T354 PolarHBondContact O-N 2.92Å; T354-G358 WeakPolarHBondContact O-CA 3.17Å; T354-G358 PolarHBondContact O-N 3.27Å
355	S	83.7	Confident	84	Confident	12 Å²	12	54.9 Å²	54.9	8%	0.084	29%	0.288	C	S	.	.	H	α-helix	trans	-66	-48.9	177.1	-60.6	0	0	0	0	111.8	I351 I352 L359	I351-S355 WeakPolarHBondContact O-CB 3.41Å; I351-S355 PolarHBondContact O-N 3.37Å; I351-S355 PolarHBondContact O-OG 2.9Å; I352-S355 PolarHBondContact O-N 2.84Å; S355-L359 WeakPolarHBondContact O-CB 3.46Å; S355-L359 PolarHBondContact O-N 2.89Å
356	I	84.9	Confident	83.9	Confident	32 Å²	32	56.1 Å²	56.1	16%	0.164	29%	0.293	C	S	.	.	H	α-helix	trans	-61.1	-52.1	176.8	-65	167.7	0	0	0	109.9	F48 F55 I352 G358 L359 L360 F391	F48-I356 HydrophobicContact CE2-CG2 4.48Å; F55-I356 HydrophobicContact CD2-CD1 3.92Å; F55-I356 HydrophobicContact CD2-CG1 4.18Å; F55-I356 HydrophobicContact CE2-CD1 4.16Å; F55-I356 HydrophobicContact CE2-CG1 3.89Å; I352-I356 HydrophobicContact CG2-CD1 3.68Å; I352-I356 HydrophobicContact CG2-CG1 4.45Å; I352-I356 WeakPolarHBondContact O-CG1 3.41Å; I352-I356 PolarHBondContact O-N 2.88Å; I356-G358 PolarHBondContact O-N 3.34Å; I356-L359 PolarHBondContact O-N 3.39Å; I356-L360 HydrophobicContact CG2-CD1 3.88Å; I356-L360 HydrophobicContact CG2-CG 4.22Å; I356-L360 WeakPolarHBondContact O-CB 3.33Å; I356-L360 VanDerWaalsContact O-CG 3.29Å; I356-L360 WeakPolarHBondContact O-CG 3.16Å; I356-L360 PolarHBondContact O-N 3.45Å; I356-F391 HydrophobicContact CB-CE1 4.34Å; I356-F391 HydrophobicContact CB-CZ 4.38Å; I356-F391 HydrophobicContact CG1-CE1 3.65Å; I356-F391 HydrophobicContact CG1-CZ 3.89Å; I356-F391 HydrophobicContact CG2-CZ 4.41Å
357	R	87.6	Confident	83.8	Confident	178 Å²	178	51.4 Å²	51.4	67%	0.672	27%	0.269	S	S	*	.	H	α-helix	trans	-61.5	-46.8	-178.5	179.5	-179.9	171.1	-172.9	-1.8	111.8	V353 L359 L360 I361	V353-R357 WeakPolarHBondContact O-CB 3.09Å; V353-R357 PolarHBondContact O-N 2.83Å; R357-L359 VanDerWaalsContact C-N 3.32Å; R357-L359 PolarHBondContact O-N 3.37Å; R357-L360 PolarHBondContact O-N 2.89Å; R357-I361 HydrophobicContact CG-CD1 3.78Å; R357-I361 HydrophobicContact CG-CG1 4.49Å; R357-I361 VanDerWaalsContact O-CG1 3.28Å; R357-I361 WeakPolarHBondContact O-CG1 3.46Å; R357-I361 PolarHBondContact O-N 2.84Å
358	G	81.9	Confident	83.7	Confident	33 Å²	33	53.3 Å²	53.3	34%	0.34	27%	0.274	S	S	.	.	H	α-helix	trans	-60.1	-43.9	179.7	0	0	0	0	0	111.7	T354 I356 T362	T354-G358 WeakPolarHBondContact O-CA 3.17Å; T354-G358 PolarHBondContact O-N 3.27Å; I356-G358 PolarHBondContact O-N 3.34Å; G358-T362 WeakPolarHBondContact O-CB 3.39Å; G358-T362 PolarHBondContact O-N 3.45Å; G358-T362 VanDerWaalsContact O-N 3.07Å; G358-T362 PolarHBondContact O-OG1 2.97Å
359	L	83.3	Confident	83.7	Confident	3 Å²	3	57.2 Å²	57.2	2%	0.016	31%	0.306	C	S	.	.	H	α-helix	trans	-64	-52.5	175.5	-176.8	69.7	0	0	0	111.6	S355 I356 R357 I361 T362 L363 M387 Y390 F391	S355-L359 WeakPolarHBondContact O-CB 3.46Å; S355-L359 PolarHBondContact O-N 2.89Å; I356-L359 PolarHBondContact O-N 3.39Å; R357-L359 VanDerWaalsContact C-N 3.32Å; R357-L359 PolarHBondContact O-N 3.37Å; L359-I361 VanDerWaalsContact C-N 3.3Å; L359-I361 PolarHBondContact O-N 3.43Å; L359-T362 CarbonylContact O-C 3.6Å; L359-T362 WeakPolarHBondContact O-CB 3.44Å; L359-T362 PolarHBondContact O-N 3.29Å; L359-L363 HydrophobicContact CD1-CD1 4.24Å; L359-L363 HydrophobicContact CD1-CD2 4.33Å; L359-L363 HydrophobicContact CD1-CG 4.13Å; L359-L363 HydrophobicContact CD2-CD1 4.34Å; L359-L363 HydrophobicContact CG-CD1 3.8Å; L359-L363 HydrophobicContact CG-CG 4.1Å; L359-L363 WeakPolarHBondContact O-CB 3.39Å; L359-L363 VanDerWaalsContact O-CG 3.27Å; L359-L363 WeakPolarHBondContact O-CG 3.16Å; L359-L363 PolarHBondContact O-N 2.83Å; L359-M387 HydrophobicContact CD2-CB 4.22Å; L359-M387 HydrophobicContact CD2-CG 3.72Å; L359-Y390 HydrophobicContact CB-CD1 4.34Å; L359-Y390 HydrophobicContact CB-CE1 4.11Å; L359-Y390 HydrophobicContact CD1-CD1 3.96Å; L359-Y390 HydrophobicContact CD1-CD2 4.06Å; L359-Y390 HydrophobicContact CD1-CE1 4.37Å; L359-Y390 HydrophobicContact CD1-CE2 4.45Å; L359-Y390 HydrophobicContact CD1-CG 3.79Å; L359-Y390 HydrophobicContact CD2-CD1 3.54Å; L359-Y390 HydrophobicContact CD2-CE1 4.09Å; L359-Y390 HydrophobicContact CD2-CG 4.09Å; L359-Y390 HydrophobicContact CG-CD1 4.15Å; L359-Y390 HydrophobicContact CG-CE1 4.43Å; L359-Y390 HydrophobicContact CG-CG 4.47Å; L359-F391 HydrophobicContact CD2-CD1 4.15Å; L359-F391 HydrophobicContact CD2-CD2 4.17Å; L359-F391 HydrophobicContact CD2-CE1 3.64Å; L359-F391 HydrophobicContact CD2-CE2 3.72Å; L359-F391 HydrophobicContact CD2-CG 4.43Å; L359-F391 HydrophobicContact CD2-CZ 3.44Å; L359-F391 VanDerWaalsContact CD2-CZ 3.44Å
360	L	85.4	Confident	83.6	Confident	16 Å²	16	60.3 Å²	60.3	8%	0.084	32%	0.317	C	S	.	.	H	α-helix	trans	-58.9	-39.6	-178	-70	-176.7	0	0	0	112.6	F24 F48 I356 R357 T364	F24-L360 HydrophobicContact CD1-CD2 4.16Å; F24-L360 HydrophobicContact CD2-CD1 4.34Å; F24-L360 HydrophobicContact CE1-CB 4.5Å; F24-L360 HydrophobicContact CE1-CD2 3.63Å; F24-L360 HydrophobicContact CE1-CG 4.45Å; F24-L360 HydrophobicContact CE2-CB 4.19Å; F24-L360 HydrophobicContact CE2-CD1 4.12Å; F24-L360 HydrophobicContact CZ-CB 3.83Å; F24-L360 HydrophobicContact CZ-CD1 4.26Å; F24-L360 HydrophobicContact CZ-CD2 3.84Å; F24-L360 HydrophobicContact CZ-CG 4.18Å; F48-L360 HydrophobicContact CD2-CD2 4.42Å; F48-L360 HydrophobicContact CE2-CD1 4.18Å; F48-L360 HydrophobicContact CE2-CD2 4.03Å; I356-L360 HydrophobicContact CG2-CD1 3.88Å; I356-L360 HydrophobicContact CG2-CG 4.22Å; I356-L360 WeakPolarHBondContact O-CB 3.33Å; I356-L360 VanDerWaalsContact O-CG 3.29Å; I356-L360 WeakPolarHBondContact O-CG 3.16Å; I356-L360 PolarHBondContact O-N 3.45Å; R357-L360 PolarHBondContact O-N 2.89Å; L360-T364 WeakPolarHBondContact O-CB 3.49Å; L360-T364 PolarHBondContact O-N 2.86Å; L360-T364 PolarHBondContact O-OG1 2.84Å
361	I	84.6	Confident	83.1	Confident	76 Å²	76	56.1 Å²	56.1	39%	0.39	30%	0.297	S	S	.	.	H	α-helix	trans	-64.7	-44.9	174.7	-67.7	169.1	0	0	0	110.6	R357 L359 T364 K365	R357-I361 HydrophobicContact CG-CD1 3.78Å; R357-I361 HydrophobicContact CG-CG1 4.49Å; R357-I361 VanDerWaalsContact O-CG1 3.28Å; R357-I361 WeakPolarHBondContact O-CG1 3.46Å; R357-I361 PolarHBondContact O-N 2.84Å; L359-I361 VanDerWaalsContact C-N 3.3Å; L359-I361 PolarHBondContact O-N 3.43Å; I361-T364 PolarHBondContact O-N 3.08Å; I361-K365 HydrophobicContact CG2-CD 4.35Å; I361-K365 WeakPolarHBondContact O-CG 3.43Å; I361-K365 PolarHBondContact O-N 3.39Å
362	T	82.4	Confident	82.7	Confident	59 Å²	59	56.5 Å²	56.5	36%	0.362	30%	0.304	S	S	.	.	H	α-helix	trans	-64.1	-45.2	179.8	-56.8	0	0	0	0	111.3	L161 G358 L359 T364 K365 F366	L161-T362 HydrophobicContact CD1-CG2 4.36Å; L161-T362 HydrophobicContact CD2-CG2 4.06Å; G358-T362 WeakPolarHBondContact O-CB 3.39Å; G358-T362 PolarHBondContact O-N 3.45Å; G358-T362 VanDerWaalsContact O-N 3.07Å; G358-T362 PolarHBondContact O-OG1 2.97Å; L359-T362 CarbonylContact O-C 3.6Å; L359-T362 WeakPolarHBondContact O-CB 3.44Å; L359-T362 PolarHBondContact O-N 3.29Å; T362-T364 VanDerWaalsContact C-N 3.32Å; T362-T364 PolarHBondContact O-N 3.07Å; T362-K365 PolarHBondContact O-N 3.14Å; T362-F366 WeakPolarHBondContact O-CB 3.2Å; T362-F366 PolarHBondContact O-N 2.82Å
363	L	82.9	Confident	82	Confident	9 Å²	9	59.9 Å²	59.9	5%	0.047	33%	0.329	C	S	.	.	H	α-helix	trans	-60.5	-42	175.9	-66.8	175.1	0	0	0	111.2	L359 F366 F367 L383 I386 M387	L359-L363 HydrophobicContact CD1-CD1 4.24Å; L359-L363 HydrophobicContact CD1-CD2 4.33Å; L359-L363 HydrophobicContact CD1-CG 4.13Å; L359-L363 HydrophobicContact CD2-CD1 4.34Å; L359-L363 HydrophobicContact CG-CD1 3.8Å; L359-L363 HydrophobicContact CG-CG 4.1Å; L359-L363 WeakPolarHBondContact O-CB 3.39Å; L359-L363 VanDerWaalsContact O-CG 3.27Å; L359-L363 WeakPolarHBondContact O-CG 3.16Å; L359-L363 PolarHBondContact O-N 2.83Å; L363-F366 PolarHBondContact O-N 3.39Å; L363-F367 VanDerWaalsContact O-CB 3.25Å; L363-F367 WeakPolarHBondContact O-CB 3.28Å; L363-F367 PolarHBondContact O-N 2.88Å; L363-L383 HydrophobicContact CB-CD2 4Å; L363-L383 HydrophobicContact CD2-CB 4.17Å; L363-L383 HydrophobicContact CD2-CD2 3.34Å; L363-L383 HydrophobicContact CD2-CG 4.34Å; L363-L383 HydrophobicContact CG-CD2 4.23Å; L363-I386 HydrophobicContact CD2-CG2 4.07Å; L363-M387 HydrophobicContact CD1-CB 3.89Å; L363-M387 HydrophobicContact CD1-CG 4.12Å; L363-M387 HydrophobicContact CD1-SD 4.27Å
364	T	83.1	Confident	81.3	Confident	13 Å²	13	63.3 Å²	63.3	8%	0.08	34%	0.336	C	S	.	.	H	α-helix	trans	-63.2	-46.9	177.4	-58.2	0	0	0	0	111.4	Q28 L360 I361 T362 F367 Y368	Q28-T364 HydrophobicContact CG-CG2 3.8Å; L360-T364 WeakPolarHBondContact O-CB 3.49Å; L360-T364 PolarHBondContact O-N 2.86Å; L360-T364 PolarHBondContact O-OG1 2.84Å; I361-T364 PolarHBondContact O-N 3.08Å; T362-T364 VanDerWaalsContact C-N 3.32Å; T362-T364 PolarHBondContact O-N 3.07Å; T364-F367 WeakPolarHBondContact O-CB 3.36Å; T364-F367 PolarHBondContact O-N 3.45Å; T364-Y368 HydrophobicContact CG2-CD2 3.76Å; T364-Y368 HydrophobicContact CG2-CE2 3.32Å; T364-Y368 WeakPolarHBondContact O-CD2 3.22Å; T364-Y368 PolarHBondContact O-N 3.3Å
365	K	82.6	Confident	81.1	Confident	149 Å²	149	61.2 Å²	61.2	65%	0.648	32%	0.324	S	S	*	.	H	α-helix	trans	-62.3	-44.4	176.9	-72.9	-178.9	178.2	-175	0	111.8	I361 T362 Y368 A369	I361-K365 HydrophobicContact CG2-CD 4.35Å; I361-K365 WeakPolarHBondContact O-CG 3.43Å; I361-K365 PolarHBondContact O-N 3.39Å; T362-K365 PolarHBondContact O-N 3.14Å; K365-Y368 PolarHBondContact O-N 3.31Å; K365-A369 WeakPolarHBondContact O-CB 3.48Å; K365-A369 PolarHBondContact O-N 3.41Å
366	F	81.2	Confident	81.2	Confident	100 Å²	100	60.8 Å²	60.8	44%	0.439	32%	0.322	S	S	.	.	H	α-helix	trans	-65.9	-39.7	178.4	-170.2	-93.8	0	0	0	111.7	T362 L363 A369 I370 L383	T362-F366 WeakPolarHBondContact O-CB 3.2Å; T362-F366 PolarHBondContact O-N 2.82Å; L363-F366 PolarHBondContact O-N 3.39Å; F366-A369 PolarHBondContact O-N 3.47Å; F366-I370 HydrophobicContact CD1-CD1 3.85Å; F366-I370 HydrophobicContact CD2-CD1 3.75Å; F366-I370 HydrophobicContact CE1-CD1 3.41Å; F366-I370 VanDerWaalsContact CE1-CD1 3.41Å; F366-I370 HydrophobicContact CE2-CD1 3.27Å; F366-I370 HydrophobicContact CG-CD1 4.03Å; F366-I370 HydrophobicContact CZ-CD1 3.11Å; F366-I370 PolarHBondContact O-N 3.02Å; F366-L383 HydrophobicContact CD1-CD2 3.89Å
367	F	82.8	Confident	81.3	Confident	1 Å²	1	60.5 Å²	60.5	0%	0.004	32%	0.32	C	S	.	.	H	α-helix	trans	-56	-58.2	173.5	-175	-104.2	0	0	0	109.7	L29 Y33 I35 L363 T364 A369 I370 S371 I379 V380 L383	L29-F367 HydrophobicContact CD2-CB 4.22Å; L29-F367 HydrophobicContact CD2-CD1 4.27Å; L29-F367 HydrophobicContact CD2-CD2 3.88Å; L29-F367 HydrophobicContact CD2-CE2 4.3Å; L29-F367 HydrophobicContact CD2-CG 3.85Å; L29-F367 WeakPolarHBondContact O-CE1 3.23Å; Y33-F367 AromaticContact CD2-CE1 3.71Å; Y33-F367 HydrophobicContact CD2-CE1 3.71Å; Y33-F367 HydrophobicContact CD2-CZ 4.19Å; Y33-F367 HydrophobicContact CE2-CE1 4.26Å; Y33-F367 HydrophobicContact CG-CE1 4.35Å; Y33-F367 HydrophobicContact CG-CZ 4.38Å; I35-F367 HydrophobicContact CD1-CZ 4.45Å; L363-F367 VanDerWaalsContact O-CB 3.25Å; L363-F367 WeakPolarHBondContact O-CB 3.28Å; L363-F367 PolarHBondContact O-N 2.88Å; T364-F367 WeakPolarHBondContact O-CB 3.36Å; T364-F367 PolarHBondContact O-N 3.45Å; F367-A369 VanDerWaalsContact C-N 3.28Å; F367-A369 PolarHBondContact O-N 3.02Å; F367-I370 PolarHBondContact O-N 3.5Å; F367-I370 VanDerWaalsContact O-N 3.15Å; F367-S371 WeakPolarHBondContact O-CA 3.45Å; F367-S371 WeakPolarHBondContact O-CB 3.37Å; F367-S371 PolarHBondContact O-N 3.13Å; F367-S371 PolarHBondContact O-OG 3.36Å; F367-I379 HydrophobicContact CD2-CG2 3.71Å; F367-I379 HydrophobicContact CE2-CG2 4.16Å; F367-V380 HydrophobicContact CD2-CG2 4.23Å; F367-V380 HydrophobicContact CE2-CG2 3.55Å; F367-V380 HydrophobicContact CZ-CG2 4.27Å; F367-L383 HydrophobicContact CB-CD1 3.71Å; F367-L383 HydrophobicContact CD2-CD1 3.54Å; F367-L383 HydrophobicContact CG-CD1 4.04Å
368	Y	80.9	Confident	81.4	Confident	82 Å²	82	52.8 Å²	52.8	32%	0.322	29%	0.293	S	S	.	.	H	α-helix	trans	-62.5	-31.2	-178.1	-67.5	-46.8	0	0	0	114.3	Q28 Y33 T364 K365 I370 S371	Q28-Y368 PolarHBondContact O-OH 2.93Å; Y33-Y368 HydrophobicContact CE2-CD1 4.44Å; T364-Y368 HydrophobicContact CG2-CD2 3.76Å; T364-Y368 HydrophobicContact CG2-CE2 3.32Å; T364-Y368 WeakPolarHBondContact O-CD2 3.22Å; T364-Y368 PolarHBondContact O-N 3.3Å; K365-Y368 PolarHBondContact O-N 3.31Å; Y368-I370 VanDerWaalsContact C-N 3.33Å; Y368-S371 WeakPolarHBondContact CA-OG 3.47Å
369	A	81.1	Confident	81.7	Confident	83 Å²	83	51.7 Å²	51.7	69%	0.686	28%	0.279	S	S	*	.	H	α-helix	trans	-70.4	-28.7	178.6	0	0	0	0	0	113.2	K365 F366 F367	K365-A369 WeakPolarHBondContact O-CB 3.48Å; K365-A369 PolarHBondContact O-N 3.41Å; F366-A369 PolarHBondContact O-N 3.47Å; F367-A369 VanDerWaalsContact C-N 3.28Å; F367-A369 PolarHBondContact O-N 3.02Å
370	I	81.9	Confident	82	Confident	85 Å²	85	51.6 Å²	51.6	44%	0.436	28%	0.278	S	S	.	.	H	α-helix	trans	-118.4	-15.1	-170.4	-64.3	164	0	0	0	112.2	F366 F367 Y368 S372 I379	F366-I370 HydrophobicContact CD1-CD1 3.85Å; F366-I370 HydrophobicContact CD2-CD1 3.75Å; F366-I370 HydrophobicContact CE1-CD1 3.41Å; F366-I370 VanDerWaalsContact CE1-CD1 3.41Å; F366-I370 HydrophobicContact CE2-CD1 3.27Å; F366-I370 HydrophobicContact CG-CD1 4.03Å; F366-I370 HydrophobicContact CZ-CD1 3.11Å; F366-I370 PolarHBondContact O-N 3.02Å; F367-I370 PolarHBondContact O-N 3.5Å; F367-I370 VanDerWaalsContact O-N 3.15Å; Y368-I370 VanDerWaalsContact C-N 3.33Å; I370-S372 PolarHBondContact O-N 3.21Å; I370-I379 HydrophobicContact CG2-CD1 3.92Å; I370-I379 HydrophobicContact CG2-CG1 4.42Å; I370-I379 WeakPolarHBondContact O-CD1 2.94Å
371	S	75.8	Confident	82.3	Confident	12 Å²	12	50.8 Å²	50.8	8%	0.084	27%	0.274	C	S	.	.			trans	-62.1	110.1	-175.2	49.8	0	0	0	0	111.7	Y33 F367 Y368	Y33-S371 VanDerWaalsContact CE1-O 3.25Å; Y33-S371 WeakPolarHBondContact CE1-O 3.47Å; Y33-S371 WeakPolarHBondContact CE2-OG 3.4Å; Y33-S371 VanDerWaalsContact CZ-CB 3.47Å; Y33-S371 VanDerWaalsContact CZ-O 3.31Å; Y33-S371 PolarHBondContact OH-O 3.2Å; Y33-S371 PolarHBondContact OH-OG 2.85Å; F367-S371 WeakPolarHBondContact O-CA 3.45Å; F367-S371 WeakPolarHBondContact O-CB 3.37Å; F367-S371 PolarHBondContact O-N 3.13Å; F367-S371 PolarHBondContact O-OG 3.36Å; Y368-S371 WeakPolarHBondContact CA-OG 3.47Å
372	S	75.4	Confident	82.7	Confident	57 Å²	57	50.9 Å²	50.9	40%	0.399	28%	0.275	S	S	.	.			trans	-104.4	148.9	164.4	-177.7	0	0	0	0	109.5	I370 K374 S375 S376	I370-S372 PolarHBondContact O-N 3.21Å; S372-K374 PolarHBondContact O-N 3.29Å; S372-S375 PolarHBondContact O-N 3.23Å; S372-S375 VanDerWaalsContact O-N 3.08Å; S372-S376 PolarHBondContact O-N 3.36Å; S372-S376 VanDerWaalsContact O-N 3.1Å
373	S	70.6	Confident	83	Confident	82 Å²	82	48.1 Å²	48.1	57%	0.573	26%	0.258	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.2	-23.2	178.1	59	0	0	0	0	113.7
374	K	71.9	Confident	83.5	Confident	166 Å²	166	47.7 Å²	47.7	72%	0.722	26%	0.256	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.1	-24.7	178.8	-66.9	-173.4	-179.6	174.3	0	114.2	N101 S372	N101-K374 PolarHBondContact ND2-O 3.31Å; N101-K374 PolarHBondContact OD1-O 3.05Å; S372-K374 PolarHBondContact O-N 3.29Å
375	S	80.2	Confident	84	Confident	37 Å²	37	47.8 Å²	47.8	26%	0.259	26%	0.255	S	S	.	.	T	Hydrogen-bonded Turn	trans	-116.8	3.7	-171.9	56.4	0	0	0	0	114	S372 N377 V378 I379	S372-S375 PolarHBondContact O-N 3.23Å; S372-S375 VanDerWaalsContact O-N 3.08Å; S375-N377 VanDerWaalsContact C-N 3.32Å; S375-N377 PolarHBondContact O-N 2.67Å; S375-V378 PolarHBondContact O-N 2.96Å; S375-I379 WeakPolarHBondContact O-CG1 3Å; S375-I379 PolarHBondContact O-N 3.26Å; S375-I379 WeakPolarHBondContact OG-CD1 3.35Å
376	S	84.3	Confident	84.5	Confident	4 Å²	4	42.8 Å²	42.8	3%	0.028	24%	0.236	C	C	.	.	H	α-helix	trans	-49.7	-46.8	-176.6	60.5	0	0	0	0	113.5	S372 V378 I379 V380	S372-S376 PolarHBondContact O-N 3.36Å; S372-S376 VanDerWaalsContact O-N 3.1Å; S376-V378 PolarHBondContact O-N 3.36Å; S376-I379 PolarHBondContact O-N 2.92Å; S376-V380 WeakPolarHBondContact O-CG2 3.38Å; S376-V380 PolarHBondContact O-N 2.87Å
377	N	87.8	Confident	85	Confident	26 Å²	26	38 Å²	38	14%	0.139	22%	0.215	C	C	.	.	H	α-helix	trans	-58.7	-44.4	177.8	-68.3	-23	0	0	0	112.7	I35 V40 F97 S375 L381	I35-N377 VanDerWaalsContact CG2-OD1 3.31Å; I35-N377 WeakPolarHBondContact CG2-OD1 3.42Å; V40-N377 HydrophobicContact CG2-CB 4.15Å; F97-N377 HydrophobicContact CD1-CB 4.15Å; F97-N377 HydrophobicContact CE1-CB 4.45Å; F97-N377 HydrophobicContact CG-CB 4.22Å; S375-N377 VanDerWaalsContact C-N 3.32Å; S375-N377 PolarHBondContact O-N 2.67Å; N377-L381 WeakPolarHBondContact O-CG 3.09Å; N377-L381 PolarHBondContact O-N 3.44Å; N377-L381 VanDerWaalsContact O-N 3.13Å
378	V	89.4	Confident	85.5	Confident	15 Å²	15	38 Å²	38	9%	0.091	21%	0.214	C	C	.	.	H	α-helix	trans	-67.2	-44.2	179.8	178.4	0	0	0	0	109.9	I94 F97 I98 S375 S376 V380 L381 L382	I94-V378 HydrophobicContact CG2-CG1 4.41Å; F97-V378 HydrophobicContact CB-CG2 3.62Å; I98-V378 HydrophobicContact CD1-CG1 4.28Å; I98-V378 HydrophobicContact CG1-CG1 3.9Å; I98-V378 HydrophobicContact CG1-CG2 4.02Å; S375-V378 PolarHBondContact O-N 2.96Å; S376-V378 PolarHBondContact O-N 3.36Å; V378-V380 VanDerWaalsContact C-N 3.34Å; V378-V380 PolarHBondContact O-N 2.98Å; V378-L381 PolarHBondContact O-N 3.24Å; V378-L382 HydrophobicContact CG1-CD1 4.02Å; V378-L382 HydrophobicContact CG1-CG 4.39Å; V378-L382 WeakPolarHBondContact O-CG 3.41Å; V378-L382 PolarHBondContact O-N 3.01Å
379	I	88.4	Confident	86	Confident	11 Å²	11	34.7 Å²	34.7	6%	0.056	20%	0.202	C	C	.	.	H	α-helix	trans	-61.9	-44.1	179.5	-63.3	167.4	0	0	0	110.1	F367 I370 S375 S376 L381 L382 L383	F367-I379 HydrophobicContact CD2-CG2 3.71Å; F367-I379 HydrophobicContact CE2-CG2 4.16Å; I370-I379 HydrophobicContact CG2-CD1 3.92Å; I370-I379 HydrophobicContact CG2-CG1 4.42Å; I370-I379 WeakPolarHBondContact O-CD1 2.94Å; S375-I379 WeakPolarHBondContact O-CG1 3Å; S375-I379 PolarHBondContact O-N 3.26Å; S375-I379 WeakPolarHBondContact OG-CD1 3.35Å; S376-I379 PolarHBondContact O-N 2.92Å; I379-L381 PolarHBondContact O-N 3.39Å; I379-L382 WeakPolarHBondContact O-CB 3.17Å; I379-L382 PolarHBondContact O-N 3.24Å; I379-L383 HydrophobicContact CG2-CD1 4.14Å; I379-L383 HydrophobicContact CG2-CG 4.43Å; I379-L383 VanDerWaalsContact O-CG 3.26Å; I379-L383 WeakPolarHBondContact O-CG 3.38Å; I379-L383 PolarHBondContact O-N 3.22Å
380	V	89.4	Confident	86.5	Confident	0 Å²	0	31.9 Å²	31.9	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-60.5	-43.7	175.9	165.4	0	0	0	0	112.5	F25 L29 I35 V40 F44 F367 S376 V378 L382 L383 A384	F25-V380 HydrophobicContact CD2-CG1 4.46Å; F25-V380 HydrophobicContact CE2-CB 4.3Å; F25-V380 HydrophobicContact CE2-CG1 3.4Å; F25-V380 VanDerWaalsContact CE2-CG1 3.4Å; F25-V380 HydrophobicContact CE2-CG2 3.91Å; F25-V380 HydrophobicContact CZ-CG1 3.95Å; F25-V380 HydrophobicContact CZ-CG2 4.2Å; L29-V380 HydrophobicContact CD2-CG2 4.36Å; I35-V380 HydrophobicContact CD1-CG2 3.66Å; V40-V380 HydrophobicContact CG1-CB 3.83Å; V40-V380 HydrophobicContact CG1-CG1 3.37Å; F44-V380 HydrophobicContact CB-CG1 4.29Å; F44-V380 HydrophobicContact CD2-CG1 4.14Å; F44-V380 HydrophobicContact CG-CG1 4.48Å; F367-V380 HydrophobicContact CD2-CG2 4.23Å; F367-V380 HydrophobicContact CE2-CG2 3.55Å; F367-V380 HydrophobicContact CZ-CG2 4.27Å; S376-V380 WeakPolarHBondContact O-CG2 3.38Å; S376-V380 PolarHBondContact O-N 2.87Å; V378-V380 VanDerWaalsContact C-N 3.34Å; V378-V380 PolarHBondContact O-N 2.98Å; V380-L382 VanDerWaalsContact C-N 3.32Å; V380-L382 PolarHBondContact O-N 2.87Å; V380-L383 WeakPolarHBondContact O-CB 3.45Å; V380-L383 PolarHBondContact O-N 3.48Å; V380-A384 PolarHBondContact O-N 2.96Å
381	L	92.4	Very high	86.9	Confident	0 Å²	0	27.9 Å²	27.9	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-66.8	-36.1	177.9	-69.9	170.2	0	0	0	112	V40 I43 V90 I94 F97 N377 V378 I379 L383 A384 Q385	V40-L381 HydrophobicContact CG1-CD2 4.25Å; V40-L381 HydrophobicContact CG1-CG 4.12Å; V40-L381 HydrophobicContact CG2-CD1 4.3Å; V40-L381 HydrophobicContact CG2-CG 4.37Å; I43-L381 HydrophobicContact CB-CD2 4.18Å; I43-L381 HydrophobicContact CD1-CD2 4.16Å; I43-L381 HydrophobicContact CG2-CD2 3.81Å; V90-L381 WeakPolarHBondContact CG1-O 3.5Å; I94-L381 HydrophobicContact CD1-CB 4.26Å; I94-L381 HydrophobicContact CG1-CB 3.53Å; I94-L381 HydrophobicContact CG1-CD1 4.3Å; F97-L381 HydrophobicContact CD2-CD1 3.37Å; F97-L381 HydrophobicContact CE2-CD1 3.78Å; F97-L381 HydrophobicContact CG-CD1 4.47Å; N377-L381 WeakPolarHBondContact O-CG 3.09Å; N377-L381 PolarHBondContact O-N 3.44Å; N377-L381 VanDerWaalsContact O-N 3.13Å; V378-L381 PolarHBondContact O-N 3.24Å; I379-L381 PolarHBondContact O-N 3.39Å; L381-L383 VanDerWaalsContact C-N 3.32Å; L381-A384 WeakPolarHBondContact O-CB 3.21Å; L381-A384 PolarHBondContact O-N 3.44Å; L381-Q385 WeakPolarHBondContact O-CB 3.32Å; L381-Q385 PolarHBondContact O-N 2.68Å
382	L	91.8	Very high	87.6	Confident	77 Å²	77	27.3 Å²	27.3	40%	0.403	15%	0.15	S	C	.	.	H	α-helix	trans	-63	-39.6	171.2	-72	170.1	0	0	0	111.6	I94 V378 I379 V380 Q385 I386	I94-L382 HydrophobicContact CD1-CD2 3.89Å; I94-L382 HydrophobicContact CD1-CG 4.36Å; I94-L382 HydrophobicContact CG2-CD2 4.44Å; V378-L382 HydrophobicContact CG1-CD1 4.02Å; V378-L382 HydrophobicContact CG1-CG 4.39Å; V378-L382 WeakPolarHBondContact O-CG 3.41Å; V378-L382 PolarHBondContact O-N 3.01Å; I379-L382 WeakPolarHBondContact O-CB 3.17Å; I379-L382 PolarHBondContact O-N 3.24Å; V380-L382 VanDerWaalsContact C-N 3.32Å; V380-L382 PolarHBondContact O-N 2.87Å; L382-Q385 WeakPolarHBondContact O-CB 3.32Å; L382-Q385 PolarHBondContact O-N 3.25Å; L382-I386 WeakPolarHBondContact O-CB 2.93Å; L382-I386 VanDerWaalsContact O-CG1 3.29Å; L382-I386 WeakPolarHBondContact O-CG1 3.19Å; L382-I386 PolarHBondContact O-N 3.24Å
383	L	89.8	Confident	88.3	Confident	1 Å²	1	24.6 Å²	24.6	1%	0.005	13%	0.131	C	C	.	.	H	α-helix	trans	-65.1	-41.6	173.9	-68.3	169.9	0	0	0	111.4	L29 L363 F366 F367 I379 V380 L381 Q385 I386 M387	L29-L383 HydrophobicContact CD2-CD1 3.88Å; L363-L383 HydrophobicContact CB-CD2 4Å; L363-L383 HydrophobicContact CD2-CB 4.17Å; L363-L383 HydrophobicContact CD2-CD2 3.34Å; L363-L383 HydrophobicContact CD2-CG 4.34Å; L363-L383 HydrophobicContact CG-CD2 4.23Å; F366-L383 HydrophobicContact CD1-CD2 3.89Å; F367-L383 HydrophobicContact CB-CD1 3.71Å; F367-L383 HydrophobicContact CD2-CD1 3.54Å; F367-L383 HydrophobicContact CG-CD1 4.04Å; I379-L383 HydrophobicContact CG2-CD1 4.14Å; I379-L383 HydrophobicContact CG2-CG 4.43Å; I379-L383 VanDerWaalsContact O-CG 3.26Å; I379-L383 WeakPolarHBondContact O-CG 3.38Å; I379-L383 PolarHBondContact O-N 3.22Å; V380-L383 WeakPolarHBondContact O-CB 3.45Å; V380-L383 PolarHBondContact O-N 3.48Å; L381-L383 VanDerWaalsContact C-N 3.32Å; L383-Q385 VanDerWaalsContact C-N 3.33Å; L383-Q385 PolarHBondContact O-N 2.81Å; L383-I386 PolarHBondContact O-N 3.09Å; L383-M387 WeakPolarHBondContact O-CB 3.1Å; L383-M387 PolarHBondContact O-N 2.89Å
384	A	92.6	Very high	89.1	Confident	0 Å²	0	20.9 Å²	20.9	0%	0	10%	0.104	C	C	.	.	H	α-helix	trans	-60.6	-42.8	173.8	0	0	0	0	0	111.5	F44 V380 L381 M387 G388	F44-A384 HydrophobicContact CD2-CB 3.96Å; V380-A384 PolarHBondContact O-N 2.96Å; L381-A384 WeakPolarHBondContact O-CB 3.21Å; L381-A384 PolarHBondContact O-N 3.44Å; A384-M387 PolarHBondContact O-N 3.31Å; A384-G388 PolarHBondContact O-N 3.35Å
385	Q	94	Very high	89.8	Confident	15 Å²	15	13 Å²	13	7%	0.07	7%	0.07	C	C	.	.	H	α-helix	trans	-60	-54.6	175.8	-172.1	66.3	18.3	0	0	111.1	L86 V90 I94 L381 L382 L383 M387 G388 M389	L86-Q385 PolarHBondContact O-NE2 3.14Å; L86-Q385 PolarHBondContact O-OE1 3.14Å; L86-Q385 VanDerWaalsContact O-OE1 3.13Å; V90-Q385 VanDerWaalsContact CB-OE1 3.26Å; V90-Q385 HydrophobicContact CG1-CB 3.85Å; V90-Q385 HydrophobicContact CG1-CG 4.47Å; I94-Q385 HydrophobicContact CD1-CB 4.41Å; L381-Q385 WeakPolarHBondContact O-CB 3.32Å; L381-Q385 PolarHBondContact O-N 2.68Å; L382-Q385 WeakPolarHBondContact O-CB 3.32Å; L382-Q385 PolarHBondContact O-N 3.25Å; L383-Q385 VanDerWaalsContact C-N 3.33Å; L383-Q385 PolarHBondContact O-N 2.81Å; Q385-M387 VanDerWaalsContact C-N 3.27Å; Q385-M387 PolarHBondContact O-N 3.17Å; Q385-G388 PolarHBondContact O-N 2.7Å; Q385-M389 HydrophobicContact CG-CE 3.74Å; Q385-M389 HydrophobicContact CG-SD 4.14Å; Q385-M389 WeakPolarHBondContact O-CB 3.33Å; Q385-M389 VanDerWaalsContact O-CG 3.23Å; Q385-M389 WeakPolarHBondContact O-CG 3.47Å; Q385-M389 PolarHBondContact O-N 2.94Å
386	I	92.3	Very high	90	Very high	45 Å²	45	11.4 Å²	11.4	23%	0.231	6%	0.059	C	C	.	.	H	α-helix	trans	-57.3	-44.3	178.6	-72.2	167.2	0	0	0	110.3	L157 L363 L382 L383 Y390	L157-I386 HydrophobicContact CD1-CB 4.48Å; L157-I386 HydrophobicContact CD1-CG1 4.24Å; L157-I386 HydrophobicContact CD1-CG2 4.22Å; L363-I386 HydrophobicContact CD2-CG2 4.07Å; L382-I386 WeakPolarHBondContact O-CB 2.93Å; L382-I386 VanDerWaalsContact O-CG1 3.29Å; L382-I386 WeakPolarHBondContact O-CG1 3.19Å; L382-I386 PolarHBondContact O-N 3.24Å; L383-I386 PolarHBondContact O-N 3.09Å; I386-Y390 WeakPolarHBondContact O-CB 3.49Å; I386-Y390 PolarHBondContact O-N 2.96Å
387	M	91.5	Very high	89.8	Confident	0 Å²	0	12 Å²	12	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-62.1	-52.1	-178.6	179.2	-176.5	72.6	0	0	112.3	F44 T47 F48 L359 L363 L383 A384 Q385 Y390 F391	F44-M387 HydrophobicContact CE2-CE 4.25Å; F44-M387 HydrophobicContact CE2-SD 4.18Å; F44-M387 HydrophobicContact CZ-CE 4.44Å; F44-M387 HydrophobicContact CZ-SD 4.1Å; T47-M387 HydrophobicContact CG2-CE 3.88Å; F48-M387 HydrophobicContact CB-CE 3.73Å; F48-M387 HydrophobicContact CB-SD 4.27Å; F48-M387 HydrophobicContact CD2-CE 4.36Å; F48-M387 HydrophobicContact CD2-SD 3.78Å; L359-M387 HydrophobicContact CD2-CB 4.22Å; L359-M387 HydrophobicContact CD2-CG 3.72Å; L363-M387 HydrophobicContact CD1-CB 3.89Å; L363-M387 HydrophobicContact CD1-CG 4.12Å; L363-M387 HydrophobicContact CD1-SD 4.27Å; L383-M387 WeakPolarHBondContact O-CB 3.1Å; L383-M387 PolarHBondContact O-N 2.89Å; A384-M387 PolarHBondContact O-N 3.31Å; Q385-M387 VanDerWaalsContact C-N 3.27Å; Q385-M387 PolarHBondContact O-N 3.17Å; M387-Y390 WeakPolarHBondContact O-CB 3.26Å; M387-Y390 PolarHBondContact O-N 3Å; M387-F391 HydrophobicContact CG-CD2 3.62Å; M387-F391 HydrophobicContact CG-CE2 3.32Å; M387-F391 HydrophobicContact CG-CZ 4.29Å; M387-F391 WeakPolarHBondContact O-CD2 3.29Å; M387-F391 WeakPolarHBondContact O-CG 3.32Å; M387-F391 PolarHBondContact O-N 2.92Å; M387-F391 HydrophobicContact SD-CE2 4.03Å
388	G	93.3	Very high	89.5	Confident	0 Å²	0	11 Å²	11	0%	0	6%	0.056	C	C	.	.	H	α-helix	trans	-67.5	-38.5	-179.3	0	0	0	0	0	112.5	L86 A384 Q385 Y390 F391 V392	L86-G388 VanDerWaalsContact CD1-C 3.49Å; A384-G388 PolarHBondContact O-N 3.35Å; Q385-G388 PolarHBondContact O-N 2.7Å; G388-Y390 VanDerWaalsContact C-N 3.35Å; G388-Y390 PolarHBondContact O-N 3.22Å; G388-F391 PolarHBondContact O-N 3.42Å; G388-V392 WeakPolarHBondContact O-CG2 3.11Å; G388-V392 PolarHBondContact O-N 3.08Å
389	M	93.3	Very high	89	Confident	13 Å²	13	11.2 Å²	11.2	6%	0.064	6%	0.055	C	C	.	.	H	α-helix	trans	-62.1	-43.4	173.6	-65.5	-173.8	-55.6	0	0	111.3	V150 I153 L157 Q385 F391 V392 S393	V150-M389 HydrophobicContact CG1-CB 4.42Å; V150-M389 HydrophobicContact CG1-CG 4.12Å; I153-M389 HydrophobicContact CB-SD 3.99Å; I153-M389 HydrophobicContact CD1-SD 4.27Å; I153-M389 HydrophobicContact CG2-CE 3.61Å; I153-M389 HydrophobicContact CG2-SD 3.51Å; I153-M389 VanDerWaalsContact CG2-SD 3.51Å; L157-M389 HydrophobicContact CD1-CE 3.75Å; Q385-M389 HydrophobicContact CG-CE 3.74Å; Q385-M389 HydrophobicContact CG-SD 4.14Å; Q385-M389 WeakPolarHBondContact O-CB 3.33Å; Q385-M389 VanDerWaalsContact O-CG 3.23Å; Q385-M389 WeakPolarHBondContact O-CG 3.47Å; Q385-M389 PolarHBondContact O-N 2.94Å; M389-F391 PolarHBondContact O-N 3.43Å; M389-V392 PolarHBondContact O-N 3.47Å; M389-S393 WeakPolarHBondContact O-CB 3.47Å; M389-S393 PolarHBondContact O-N 3.34Å; M389-S393 PolarHBondContact O-OG 2.84Å
390	Y	91.2	Very high	88.1	Confident	24 Å²	24	12.9 Å²	12.9	9%	0.094	6%	0.063	C	C	.	.	H	α-helix	trans	-59.8	-44.5	176	177.5	-84.2	0	0	0	112	M158 L359 I386 M387 G388 S393 S394	M158-Y390 HydrophobicContact CB-CD2 4.02Å; M158-Y390 HydrophobicContact CB-CE2 3.88Å; M158-Y390 HydrophobicContact CG-CD2 4.29Å; M158-Y390 HydrophobicContact CG-CE2 3.67Å; L359-Y390 HydrophobicContact CB-CD1 4.34Å; L359-Y390 HydrophobicContact CB-CE1 4.11Å; L359-Y390 HydrophobicContact CD1-CD1 3.96Å; L359-Y390 HydrophobicContact CD1-CD2 4.06Å; L359-Y390 HydrophobicContact CD1-CE1 4.37Å; L359-Y390 HydrophobicContact CD1-CE2 4.45Å; L359-Y390 HydrophobicContact CD1-CG 3.79Å; L359-Y390 HydrophobicContact CD2-CD1 3.54Å; L359-Y390 HydrophobicContact CD2-CE1 4.09Å; L359-Y390 HydrophobicContact CD2-CG 4.09Å; L359-Y390 HydrophobicContact CG-CD1 4.15Å; L359-Y390 HydrophobicContact CG-CE1 4.43Å; L359-Y390 HydrophobicContact CG-CG 4.47Å; I386-Y390 WeakPolarHBondContact O-CB 3.49Å; I386-Y390 PolarHBondContact O-N 2.96Å; M387-Y390 WeakPolarHBondContact O-CB 3.26Å; M387-Y390 PolarHBondContact O-N 3Å; G388-Y390 VanDerWaalsContact C-N 3.35Å; G388-Y390 PolarHBondContact O-N 3.22Å; Y390-S393 PolarHBondContact O-N 3.06Å; Y390-S394 WeakPolarHBondContact CE1-OG 3.47Å; Y390-S394 WeakPolarHBondContact O-CB 3.35Å; Y390-S394 PolarHBondContact O-N 3.42Å; Y390-S394 PolarHBondContact O-OG 2.92Å
391	F	90.1	Very high	87.1	Confident	0 Å²	0	14.8 Å²	14.8	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-68.8	-42.4	-179.5	-72.2	-44.8	0	0	0	112.8	S51 F55 I356 L359 M387 G388 M389 S393 S394 V395	S51-F391 WeakPolarHBondContact OG-CD2 3.43Å; F55-F391 HydrophobicContact CE2-CB 4.5Å; F55-F391 AromaticContact CE2-CD1 3.31Å; F55-F391 HydrophobicContact CE2-CD1 3.31Å; F55-F391 AromaticContact CE2-CE1 3.6Å; F55-F391 HydrophobicContact CE2-CE1 3.6Å; F55-F391 HydrophobicContact CE2-CG 4.1Å; F55-F391 AromaticContact CZ-CD1 3.59Å; F55-F391 HydrophobicContact CZ-CD1 3.59Å; F55-F391 HydrophobicContact CZ-CE1 4.18Å; F55-F391 HydrophobicContact CZ-CG 4.43Å; I356-F391 HydrophobicContact CB-CE1 4.34Å; I356-F391 HydrophobicContact CB-CZ 4.38Å; I356-F391 HydrophobicContact CG1-CE1 3.65Å; I356-F391 HydrophobicContact CG1-CZ 3.89Å; I356-F391 HydrophobicContact CG2-CZ 4.41Å; L359-F391 HydrophobicContact CD2-CD1 4.15Å; L359-F391 HydrophobicContact CD2-CD2 4.17Å; L359-F391 HydrophobicContact CD2-CE1 3.64Å; L359-F391 HydrophobicContact CD2-CE2 3.72Å; L359-F391 HydrophobicContact CD2-CG 4.43Å; L359-F391 HydrophobicContact CD2-CZ 3.44Å; L359-F391 VanDerWaalsContact CD2-CZ 3.44Å; M387-F391 HydrophobicContact CG-CD2 3.62Å; M387-F391 HydrophobicContact CG-CE2 3.32Å; M387-F391 HydrophobicContact CG-CZ 4.29Å; M387-F391 WeakPolarHBondContact O-CD2 3.29Å; M387-F391 WeakPolarHBondContact O-CG 3.32Å; M387-F391 PolarHBondContact O-N 2.92Å; M387-F391 HydrophobicContact SD-CE2 4.03Å; G388-F391 PolarHBondContact O-N 3.42Å; M389-F391 PolarHBondContact O-N 3.43Å; F391-S393 VanDerWaalsContact C-N 3.32Å; F391-S393 PolarHBondContact O-N 2.91Å; F391-S394 WeakPolarHBondContact O-CB 3.34Å; F391-S394 PolarHBondContact O-N 2.83Å; F391-V395 WeakPolarHBondContact O-CG2 3.43Å; F391-V395 PolarHBondContact O-N 3.3Å; F391-V395 VanDerWaalsContact O-N 3.07Å
392	V	90.6	Very high	86	Confident	1 Å²	1	15.1 Å²	15.1	1%	0.006	8%	0.078	C	C	.	.	H	α-helix	trans	-57.5	-46.7	172.7	171.9	0	0	0	0	110.5	M54 I82 L86 I147 V150 G388 M389 S394 V395 L396	M54-V392 HydrophobicContact CE-CG2 4.46Å; M54-V392 HydrophobicContact SD-CG2 4.01Å; I82-V392 HydrophobicContact CG1-CG2 4.25Å; I82-V392 HydrophobicContact CG2-CG2 4.24Å; L86-V392 HydrophobicContact CD1-CG2 4.05Å; I147-V392 HydrophobicContact CG1-CG1 3.9Å; V150-V392 HydrophobicContact CG1-CB 4Å; V150-V392 HydrophobicContact CG1-CG1 3.84Å; V150-V392 HydrophobicContact CG1-CG2 4.32Å; G388-V392 WeakPolarHBondContact O-CG2 3.11Å; G388-V392 PolarHBondContact O-N 3.08Å; M389-V392 PolarHBondContact O-N 3.47Å; V392-S394 PolarHBondContact O-N 3.36Å; V392-V395 PolarHBondContact O-N 3.38Å; V392-L396 WeakPolarHBondContact O-CG 3.25Å; V392-L396 PolarHBondContact O-N 3.37Å; V392-L396 VanDerWaalsContact O-N 3.11Å
393	S	89.6	Confident	85	Confident	0 Å²	0	12.9 Å²	12.9	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-66.4	-35.4	177.3	-66.5	0	0	0	0	113.9	G151 G154 V155 M389 Y390 F391 V395 L396 L397	G151-S393 WeakPolarHBondContact CA-OG 3.49Å; G151-S393 PolarHBondContact O-OG 3.34Å; G154-S393 VanDerWaalsContact C-CB 3.43Å; G154-S393 WeakPolarHBondContact CA-OG 3.21Å; V155-S393 PolarHBondContact N-OG 3.27Å; M389-S393 WeakPolarHBondContact O-CB 3.47Å; M389-S393 PolarHBondContact O-N 3.34Å; M389-S393 PolarHBondContact O-OG 2.84Å; Y390-S393 PolarHBondContact O-N 3.06Å; F391-S393 VanDerWaalsContact C-N 3.32Å; F391-S393 PolarHBondContact O-N 2.91Å; S393-V395 VanDerWaalsContact C-N 3.28Å; S393-V395 PolarHBondContact O-N 2.93Å; S393-L396 WeakPolarHBondContact O-CB 3.41Å; S393-L396 PolarHBondContact O-N 2.87Å; S393-L397 WeakPolarHBondContact O-CG 3.33Å; S393-L397 PolarHBondContact O-N 2.69Å
394	S	87.3	Confident	84.2	Confident	3 Å²	3	18.5 Å²	18.5	2%	0.021	10%	0.098	C	C	.	.	H	α-helix	trans	-60.5	-42.1	175	-61.2	0	0	0	0	110.5	Y390 F391 V392 L397 I398	Y390-S394 WeakPolarHBondContact CE1-OG 3.47Å; Y390-S394 WeakPolarHBondContact O-CB 3.35Å; Y390-S394 PolarHBondContact O-N 3.42Å; Y390-S394 PolarHBondContact O-OG 2.92Å; F391-S394 WeakPolarHBondContact O-CB 3.34Å; F391-S394 PolarHBondContact O-N 2.83Å; V392-S394 PolarHBondContact O-N 3.36Å; S394-L397 PolarHBondContact O-N 2.88Å; S394-I398 WeakPolarHBondContact O-CB 3.36Å; S394-I398 WeakPolarHBondContact O-CD1 3.45Å; S394-I398 WeakPolarHBondContact O-CG1 2.96Å; S394-I398 PolarHBondContact O-N 2.85Å
395	V	86.7	Confident	83.3	Confident	1 Å²	1	23.5 Å²	23.5	1%	0.006	12%	0.121	C	C	.	.	H	α-helix	trans	-65.8	-41.1	176.4	171	0	0	0	0	112.1	M54 F55 I58 W75 F391 V392 S393 L397 I398 R399	M54-V395 HydrophobicContact CB-CG2 3.96Å; M54-V395 HydrophobicContact CE-CB 3.87Å; M54-V395 HydrophobicContact CE-CG1 3.84Å; M54-V395 HydrophobicContact CE-CG2 3.9Å; F55-V395 HydrophobicContact CD1-CG2 3.93Å; F55-V395 HydrophobicContact CE1-CG2 3.72Å; I58-V395 HydrophobicContact CD1-CB 4.41Å; I58-V395 HydrophobicContact CD1-CG1 4.05Å; I58-V395 HydrophobicContact CD1-CG2 3.93Å; W75-V395 HydrophobicContact CH2-CG1 3.9Å; W75-V395 HydrophobicContact CZ3-CG1 4.13Å; F391-V395 WeakPolarHBondContact O-CG2 3.43Å; F391-V395 PolarHBondContact O-N 3.3Å; F391-V395 VanDerWaalsContact O-N 3.07Å; V392-V395 PolarHBondContact O-N 3.38Å; S393-V395 VanDerWaalsContact C-N 3.28Å; S393-V395 PolarHBondContact O-N 2.93Å; V395-L397 VanDerWaalsContact C-N 3.27Å; V395-L397 PolarHBondContact O-N 3.46Å; V395-I398 PolarHBondContact O-N 2.75Å; V395-R399 PolarHBondContact O-N 3.4Å
396	L	83.8	Confident	82.5	Confident	3 Å²	3	24.1 Å²	24.1	2%	0.016	12%	0.123	C	C	.	.	H	α-helix	trans	-57.5	-40.7	174.2	-67.9	177.7	0	0	0	112.1	V392 S393 R399 L414 L417 F419 Y422	V392-L396 WeakPolarHBondContact O-CG 3.25Å; V392-L396 PolarHBondContact O-N 3.37Å; V392-L396 VanDerWaalsContact O-N 3.11Å; S393-L396 WeakPolarHBondContact O-CB 3.41Å; S393-L396 PolarHBondContact O-N 2.87Å; L396-R399 WeakPolarHBondContact O-CB 3.3Å; L396-L414 HydrophobicContact CD2-CD1 3.71Å; L396-L414 HydrophobicContact CD2-CD2 3.74Å; L396-L414 HydrophobicContact CD2-CG 4.29Å; L396-L417 HydrophobicContact CD2-CD1 3.91Å; L396-F419 HydrophobicContact CD2-CE1 4.19Å; L396-Y422 HydrophobicContact CD1-CE1 4.33Å
397	L	81.5	Confident	81.9	Confident	17 Å²	17	25 Å²	25	9%	0.089	12%	0.124	C	C	.	.	H	α-helix	trans	-79.9	-35.3	-179.5	-66.4	174.6	0	0	0	112.9	V155 M158 S393 S394 V395 R399 M400 F426	V155-L397 HydrophobicContact CG2-CD1 4.13Å; V155-L397 HydrophobicContact CG2-CD2 4.44Å; V155-L397 HydrophobicContact CG2-CG 4.27Å; M158-L397 HydrophobicContact CE-CD1 4.25Å; M158-L397 HydrophobicContact SD-CD1 3.56Å; M158-L397 VanDerWaalsContact SD-CD1 3.56Å; S393-L397 WeakPolarHBondContact O-CG 3.33Å; S393-L397 PolarHBondContact O-N 2.69Å; S394-L397 PolarHBondContact O-N 2.88Å; V395-L397 VanDerWaalsContact C-N 3.27Å; V395-L397 PolarHBondContact O-N 3.46Å; L397-R399 PolarHBondContact O-N 2.8Å; L397-M400 PolarHBondContact O-N 2.64Å; L397-M400 VanDerWaalsContact O-N 3.14Å; L397-F426 HydrophobicContact CD1-CD2 4.13Å
398	I	80.4	Confident	81.5	Confident	6 Å²	6	28.9 Å²	28.9	3%	0.031	15%	0.147	C	C	.	.	H	α-helix	trans	-61.1	-33.7	176.3	-73.4	164	0	0	0	110.8	F55 I58 V348 I351 I352 S394 V395 M400 S401 M402	F55-I398 HydrophobicContact CD1-CD1 4.25Å; F55-I398 HydrophobicContact CE1-CD1 3.76Å; I58-I398 HydrophobicContact CD1-CG2 4.18Å; V348-I398 HydrophobicContact CG1-CG2 4.17Å; V348-I398 HydrophobicContact CG2-CG2 4.26Å; I351-I398 HydrophobicContact CG2-CD1 3.97Å; I351-I398 HydrophobicContact CG2-CG1 3.94Å; I352-I398 HydrophobicContact CG1-CD1 4.4Å; S394-I398 WeakPolarHBondContact O-CB 3.36Å; S394-I398 WeakPolarHBondContact O-CD1 3.45Å; S394-I398 WeakPolarHBondContact O-CG1 2.96Å; S394-I398 PolarHBondContact O-N 2.85Å; V395-I398 PolarHBondContact O-N 2.75Å; I398-M400 PolarHBondContact O-N 2.98Å; I398-M400 VanDerWaalsContact O-N 3.07Å; I398-S401 WeakPolarHBondContact O-CA 3.3Å; I398-S401 WeakPolarHBondContact O-CB 3.08Å; I398-S401 PolarHBondContact O-N 3.15Å; I398-M402 HydrophobicContact CG2-CE 3.98Å; I398-M402 HydrophobicContact CG2-CG 4.17Å; I398-M402 HydrophobicContact CG2-SD 4.09Å; I398-M402 PolarHBondContact O-N 3.23Å
399	R	79.2	Confident	81	Confident	18 Å²	18	29.4 Å²	29.4	7%	0.068	15%	0.15	C	C	.	.	G	3₁₀ helix	trans	-49	-37.8	174.6	-174.8	-167.2	171.4	-96.9	2.1	112.9	V395 L396 L397 S401 M402 R407 I410 T411 F419	V395-R399 PolarHBondContact O-N 3.4Å; L396-R399 WeakPolarHBondContact O-CB 3.3Å; L397-R399 PolarHBondContact O-N 2.8Å; R399-S401 VanDerWaalsContact C-N 3.3Å; R399-M402 PolarHBondContact O-N 2.96Å; R399-R407 HydrophobicContact CG-CB 4.35Å; R399-I410 HydrophobicContact CB-CG2 4.32Å; R399-I410 HydrophobicContact CG-CG2 4.11Å; R399-T411 VanDerWaalsContact CZ-OG1 3.32Å; R399-T411 PolarHBondContact NE-OG1 3.5Å; R399-T411 PolarHBondContact NH2-OG1 3.37Å; R399-F419 VanDerWaalsContact CD-CE1 3.42Å
400	M	68.6	Low	80.6	Confident	46 Å²	46	28.8 Å²	28.8	23%	0.227	15%	0.147	C	C	.	.	G	3₁₀ helix	trans	-77.8	-16.8	-178.8	-76.6	-75.6	-157.8	0	0	113.6	L397 I398 F419 N420 H423	L397-M400 PolarHBondContact O-N 2.64Å; L397-M400 VanDerWaalsContact O-N 3.14Å; I398-M400 PolarHBondContact O-N 2.98Å; I398-M400 VanDerWaalsContact O-N 3.07Å; M400-F419 HydrophobicContact CE-CB 3.23Å; M400-F419 HydrophobicContact CE-CG 4.31Å; M400-N420 WeakPolarHBondContact CE-OD1 3.26Å; M400-H423 WeakPolarHBondContact CB-NE2 3.29Å; M400-H423 WeakPolarHBondContact CG-NE2 3.28Å
401	S	69	Low	80.2	Confident	40 Å²	40	29.7 Å²	29.7	28%	0.28	16%	0.155	S	C	.	.	G	3₁₀ helix	trans	-90.7	-6.3	174	-51.8	0	0	0	0	112.7	I398 R399	I398-S401 WeakPolarHBondContact O-CA 3.3Å; I398-S401 WeakPolarHBondContact O-CB 3.08Å; I398-S401 PolarHBondContact O-N 3.15Å; R399-S401 VanDerWaalsContact C-N 3.3Å
402	M	70	Confident	79.9	Confident	7 Å²	7	35.5 Å²	35.5	3%	0.034	18%	0.182	C	C	.	.	S	Bend	trans	-100.1	139.5	-177.8	-69.7	-169.6	-65.4	0	0	112	I58 I62 V348 I398 R399 I410	I58-M402 HydrophobicContact CG2-CE 4.1Å; I58-M402 HydrophobicContact CG2-SD 3.55Å; I58-M402 VanDerWaalsContact CG2-SD 3.55Å; I62-M402 HydrophobicContact CD1-SD 4.06Å; I62-M402 HydrophobicContact CG1-SD 4.34Å; V348-M402 HydrophobicContact CG2-CG 3.97Å; V348-M402 HydrophobicContact CG2-SD 4.32Å; I398-M402 HydrophobicContact CG2-CE 3.98Å; I398-M402 HydrophobicContact CG2-CG 4.17Å; I398-M402 HydrophobicContact CG2-SD 4.09Å; I398-M402 PolarHBondContact O-N 3.23Å; R399-M402 PolarHBondContact O-N 2.96Å; M402-I410 HydrophobicContact CE-CD1 3.38Å
403	P	70.2	Confident	79.5	Confident	31 Å²	31	36.2 Å²	36.2	20%	0.201	19%	0.186	C	C	.	.			trans	-55	156.4	172	-25.4	33.3	0	0	0	113.3	S344 E405 Y406	S344-P403 WeakPolarHBondContact OG-CD 3.18Å; S344-P403 WeakPolarHBondContact OG-CG 3.31Å; P403-E405 PolarHBondContact O-N 3.28Å; P403-E405 VanDerWaalsContact O-N 3.15Å; P403-Y406 HydrophobicContact CB-CD2 4.03Å; P403-Y406 HydrophobicContact CB-CE2 4.35Å; P403-Y406 HydrophobicContact CG-CD2 4.1Å; P403-Y406 HydrophobicContact CG-CE2 4.33Å; P403-Y406 PolarHBondContact O-N 3.25Å
404	L	72.3	Confident	79.1	Confident	119 Å²	119	36.3 Å²	36.3	62%	0.623	19%	0.187	S	C	*	.	G	3₁₀ helix	trans	-53.3	-35.5	-179.8	-73.4	163.7	0	0	0	113.4	Y406 R407	L404-Y406 VanDerWaalsContact C-N 3.34Å; L404-Y406 PolarHBondContact O-N 3.45Å; L404-R407 WeakPolarHBondContact O-CG 3.35Å
405	E	74	Confident	78.6	Confident	104 Å²	104	36.6 Å²	36.6	49%	0.486	19%	0.19	S	C	.	.	G	3₁₀ helix	trans	-66.1	-35.3	-174.5	-60.3	177.3	171.4	0	0	112.2	P403	P403-E405 PolarHBondContact O-N 3.28Å; P403-E405 VanDerWaalsContact O-N 3.15Å
406	Y	76.7	Confident	77.8	Confident	28 Å²	28	43.5 Å²	43.5	11%	0.11	22%	0.223	C	C	.	.	G	3₁₀ helix	trans	-100.3	4.9	-175.1	-50.2	-66.5	0	0	0	113.8	E61 I62 Q341 P403 L404	E61-Y406 WeakPolarHBondContact CG-O 3.1Å; I62-Y406 HydrophobicContact CG1-CG 4.45Å; Q341-Y406 VanDerWaalsContact CB-OH 3.3Å; Q341-Y406 WeakPolarHBondContact CB-OH 3.37Å; Q341-Y406 HydrophobicContact CG-CE1 4.27Å; Q341-Y406 WeakPolarHBondContact CG-OH 3.36Å; P403-Y406 HydrophobicContact CB-CD2 4.03Å; P403-Y406 HydrophobicContact CB-CE2 4.35Å; P403-Y406 HydrophobicContact CG-CD2 4.1Å; P403-Y406 HydrophobicContact CG-CE2 4.33Å; P403-Y406 PolarHBondContact O-N 3.25Å; L404-Y406 VanDerWaalsContact C-N 3.34Å; L404-Y406 PolarHBondContact O-N 3.45Å
407	R	80.1	Confident	77.4	Confident	65 Å²	65	44.1 Å²	44.1	25%	0.245	23%	0.226	C	C	.	.			trans	-109.4	4.6	-177.3	78.5	-175.9	-162.8	-175.2	3.9	113.9	R399 L404 T411	R399-R407 HydrophobicContact CG-CB 4.35Å; L404-R407 WeakPolarHBondContact O-CG 3.35Å; R407-T411 VanDerWaalsContact O-CB 3.26Å; R407-T411 WeakPolarHBondContact O-CB 3.3Å; R407-T411 PolarHBondContact O-N 2.85Å; R407-T411 PolarHBondContact O-OG1 2.79Å
408	T	83	Confident	77.2	Confident	80 Å²	80	48.5 Å²	48.5	49%	0.491	25%	0.246	S	C	.	.	H	α-helix	trans	-62	-59	-172.9	51.7	0	0	0	0	111.6	I410 T411 E412	T408-I410 VanDerWaalsContact C-N 3.31Å; T408-I410 PolarHBondContact O-N 3.39Å; T408-T411 PolarHBondContact O-N 3.18Å; T408-T411 VanDerWaalsContact O-N 3.14Å; T408-E412 PolarHBondContact O-N 3.4Å
409	I	84.2	Confident	77	Confident	11 Å²	11	49 Å²	49	6%	0.056	25%	0.248	C	C	.	.	H	α-helix	trans	-59.4	-43.6	178.6	-63.3	-172.8	0	0	0	110.9	E61 R71 Y72 W75 T411 E412 V413	E61-I409 WeakPolarHBondContact OE2-CD1 3.25Å; R71-I409 HydrophobicContact CB-CD1 3.84Å; Y72-I409 HydrophobicContact CD2-CG2 4.22Å; W75-I409 HydrophobicContact CB-CG2 4.39Å; W75-I409 HydrophobicContact CG-CG2 4.13Å; I409-T411 VanDerWaalsContact C-N 3.31Å; I409-T411 PolarHBondContact O-N 2.98Å; I409-E412 PolarHBondContact O-N 3.45Å; I409-V413 HydrophobicContact CG2-CG2 4.02Å; I409-V413 WeakPolarHBondContact O-CB 3.45Å; I409-V413 VanDerWaalsContact O-CG2 3.22Å; I409-V413 WeakPolarHBondContact O-CG2 3.17Å; I409-V413 PolarHBondContact O-N 3.32Å
410	I	83.2	Confident	77	Confident	1 Å²	1	52 Å²	52	1%	0.005	27%	0.265	C	S	.	.	H	α-helix	trans	-62	-41.4	179.5	-63.6	172	0	0	0	110.6	I58 W75 R399 M402 T408 L414	I58-I410 HydrophobicContact CG1-CD1 4.07Å; W75-I410 HydrophobicContact CH2-CG1 4.36Å; W75-I410 HydrophobicContact CZ2-CD1 4Å; W75-I410 HydrophobicContact CZ2-CG1 3.82Å; R399-I410 HydrophobicContact CB-CG2 4.32Å; R399-I410 HydrophobicContact CG-CG2 4.11Å; M402-I410 HydrophobicContact CE-CD1 3.38Å; T408-I410 VanDerWaalsContact C-N 3.31Å; T408-I410 PolarHBondContact O-N 3.39Å; I410-L414 HydrophobicContact CG2-CD1 3.5Å; I410-L414 VanDerWaalsContact CG2-CD1 3.5Å; I410-L414 HydrophobicContact CG2-CG 4.19Å; I410-L414 WeakPolarHBondContact O-CB 3.46Å; I410-L414 WeakPolarHBondContact O-CD1 3.33Å; I410-L414 WeakPolarHBondContact O-CG 3.32Å; I410-L414 PolarHBondContact O-N 3.43Å
411	T	83.9	Confident	77.8	Confident	42 Å²	42	51.5 Å²	51.5	26%	0.258	26%	0.262	S	S	.	.	H	α-helix	trans	-66.8	-41.7	176.9	-57.4	0	0	0	0	111.6	R399 R407 T408 I409 G415	R399-T411 VanDerWaalsContact CZ-OG1 3.32Å; R399-T411 PolarHBondContact NE-OG1 3.5Å; R399-T411 PolarHBondContact NH2-OG1 3.37Å; R407-T411 VanDerWaalsContact O-CB 3.26Å; R407-T411 WeakPolarHBondContact O-CB 3.3Å; R407-T411 PolarHBondContact O-N 2.85Å; R407-T411 PolarHBondContact O-OG1 2.79Å; T408-T411 PolarHBondContact O-N 3.18Å; T408-T411 VanDerWaalsContact O-N 3.14Å; I409-T411 VanDerWaalsContact C-N 3.31Å; I409-T411 PolarHBondContact O-N 2.98Å; T411-G415 PolarHBondContact O-N 3.36Å
412	E	84.3	Confident	78.7	Confident	123 Å²	123	49.8 Å²	49.8	58%	0.575	25%	0.249	S	C	*	.	H	α-helix	trans	-67.4	-41.1	-179.7	-167.9	-178	164.6	0	0	112	Y72 T408 I409	Y72-E412 HydrophobicContact CE2-CB 4.39Å; Y72-E412 HydrophobicContact CE2-CG 3.93Å; Y72-E412 WeakPolarHBondContact CE2-OE1 3.34Å; T408-E412 PolarHBondContact O-N 3.4Å; I409-E412 PolarHBondContact O-N 3.45Å
413	V	82.2	Confident	79.3	Confident	15 Å²	15	52.3 Å²	52.3	9%	0.091	26%	0.261	C	S	.	.	H	α-helix	trans	-76.1	-36.4	-178.4	177	0	0	0	0	111.9	Y72 W75 L79 I409 G415	Y72-V413 HydrophobicContact CD2-CG2 3.7Å; Y72-V413 HydrophobicContact CE2-CG2 3.63Å; W75-V413 HydrophobicContact CB-CG1 4.3Å; W75-V413 HydrophobicContact CB-CG2 4.03Å; L79-V413 HydrophobicContact CD1-CG1 3.35Å; I409-V413 HydrophobicContact CG2-CG2 4.02Å; I409-V413 WeakPolarHBondContact O-CB 3.45Å; I409-V413 VanDerWaalsContact O-CG2 3.22Å; I409-V413 WeakPolarHBondContact O-CG2 3.17Å; I409-V413 PolarHBondContact O-N 3.32Å; V413-G415 VanDerWaalsContact C-N 3.33Å
414	L	81.4	Confident	80.1	Confident	2 Å²	2	56.4 Å²	56.4	1%	0.01	27%	0.272	C	S	.	.	H	α-helix	trans	-76.9	-22.2	176.3	-66.8	176.7	0	0	0	112.7	L79 I147 L396 I410 L417 F419	L79-L414 HydrophobicContact CD1-CD2 4.16Å; I147-L414 HydrophobicContact CD1-CD2 3.37Å; I147-L414 HydrophobicContact CG1-CD2 4.25Å; L396-L414 HydrophobicContact CD2-CD1 3.71Å; L396-L414 HydrophobicContact CD2-CD2 3.74Å; L396-L414 HydrophobicContact CD2-CG 4.29Å; I410-L414 HydrophobicContact CG2-CD1 3.5Å; I410-L414 VanDerWaalsContact CG2-CD1 3.5Å; I410-L414 HydrophobicContact CG2-CG 4.19Å; I410-L414 WeakPolarHBondContact O-CB 3.46Å; I410-L414 WeakPolarHBondContact O-CD1 3.33Å; I410-L414 WeakPolarHBondContact O-CG 3.32Å; I410-L414 PolarHBondContact O-N 3.43Å; L414-L417 HydrophobicContact CB-CD1 4.05Å; L414-L417 WeakPolarHBondContact O-CD1 3.21Å; L414-L417 WeakPolarHBondContact O-CG 3.18Å; L414-F419 HydrophobicContact CB-CZ 4.01Å; L414-F419 HydrophobicContact CD1-CE1 3.88Å; L414-F419 HydrophobicContact CD1-CZ 3.95Å
415	G	76.5	Confident	81	Confident	9 Å²	9	53.8 Å²	53.8	9%	0.093	25%	0.254	C	S	.	.			trans	80.5	-167.2	-179.4	0	0	0	0	0	114.2	E144 T411 V413 L417	E144-G415 VanDerWaalsContact OE1-CA 3.29Å; E144-G415 WeakPolarHBondContact OE1-CA 3.36Å; T411-G415 PolarHBondContact O-N 3.36Å; V413-G415 VanDerWaalsContact C-N 3.33Å; G415-L417 PolarHBondContact O-N 3.05Å
416	E	70.3	Confident	81.8	Confident	147 Å²	147	49.7 Å²	49.7	69%	0.687	24%	0.235	S	C	*	.	S	Bend	trans	-76.9	46	179.8	-63.4	-175	162.2	0	0	112.6	Q418	E416-Q418 PolarHBondContact O-N 2.65Å
417	L	73.7	Confident	82.5	Confident	15 Å²	15	49.5 Å²	49.5	8%	0.079	24%	0.236	C	C	.	.			trans	-63.7	138.6	175	-65.9	173.8	0	0	0	110.4	I147 L396 L414 G415 F419	I147-L417 HydrophobicContact CG2-CD1 3.59Å; I147-L417 HydrophobicContact CG2-CD2 4.36Å; L396-L417 HydrophobicContact CD2-CD1 3.91Å; L414-L417 HydrophobicContact CB-CD1 4.05Å; L414-L417 WeakPolarHBondContact O-CD1 3.21Å; L414-L417 WeakPolarHBondContact O-CG 3.18Å; G415-L417 PolarHBondContact O-N 3.05Å; L417-F419 HydrophobicContact CB-CD1 4.46Å; L417-F419 HydrophobicContact CB-CD2 4.28Å; L417-F419 HydrophobicContact CB-CE1 4.11Å; L417-F419 HydrophobicContact CB-CE2 3.92Å; L417-F419 HydrophobicContact CB-CZ 3.83Å; L417-F419 HydrophobicContact CD1-CE1 4.24Å; L417-F419 HydrophobicContact CD1-CZ 4.25Å; L417-F419 WeakPolarHBondContact O-CD2 3.48Å; L417-F419 WeakPolarHBondContact O-CE2 3.19Å; L417-F419 PolarHBondContact O-N 3.14Å
418	Q	77.9	Confident	83.1	Confident	110 Å²	110	48.5 Å²	48.5	51%	0.514	24%	0.237	S	C	.	.			trans	-73.2	74.5	171.1	-64.1	-170.8	-2.8	0	0	110	P132 E416 N420 F421 Y422	P132-Q418 PolarHBondContact O-OE1 2.95Å; E416-Q418 PolarHBondContact O-N 2.65Å; Q418-N420 PolarHBondContact O-N 2.94Å; Q418-N420 VanDerWaalsContact O-N 3.08Å; Q418-F421 HydrophobicContact CB-CB 4.14Å; Q418-F421 VanDerWaalsContact O-CB 3.26Å; Q418-F421 WeakPolarHBondContact O-CB 3.38Å; Q418-F421 PolarHBondContact O-N 2.84Å; Q418-Y422 WeakPolarHBondContact O-CD2 2.96Å
419	F	76.4	Confident	83.7	Confident	15 Å²	15	45.9 Å²	45.9	7%	0.066	22%	0.219	C	C	.	.	H	α-helix	trans	-55.8	-30.2	-177.4	-66.8	-77.6	0	0	0	113.6	L396 R399 M400 L414 L417 F421 Y422 H423	L396-F419 HydrophobicContact CD2-CE1 4.19Å; R399-F419 VanDerWaalsContact CD-CE1 3.42Å; M400-F419 HydrophobicContact CE-CB 3.23Å; M400-F419 HydrophobicContact CE-CG 4.31Å; L414-F419 HydrophobicContact CB-CZ 4.01Å; L414-F419 HydrophobicContact CD1-CE1 3.88Å; L414-F419 HydrophobicContact CD1-CZ 3.95Å; L417-F419 HydrophobicContact CB-CD1 4.46Å; L417-F419 HydrophobicContact CB-CD2 4.28Å; L417-F419 HydrophobicContact CB-CE1 4.11Å; L417-F419 HydrophobicContact CB-CE2 3.92Å; L417-F419 HydrophobicContact CB-CZ 3.83Å; L417-F419 HydrophobicContact CD1-CE1 4.24Å; L417-F419 HydrophobicContact CD1-CZ 4.25Å; L417-F419 WeakPolarHBondContact O-CD2 3.48Å; L417-F419 WeakPolarHBondContact O-CE2 3.19Å; L417-F419 PolarHBondContact O-N 3.14Å; F419-F421 VanDerWaalsContact C-N 3.26Å; F419-F421 PolarHBondContact O-N 2.84Å; F419-Y422 PolarHBondContact O-N 2.81Å; F419-H423 PolarHBondContact O-N 2.95Å
420	N	80.1	Confident	84.2	Confident	83 Å²	83	45.3 Å²	45.3	44%	0.444	22%	0.217	S	C	.	.	H	α-helix	trans	-60.6	-36.4	175.2	-60.9	-14.8	0	0	0	112.1	V313 M400 Q418 Y422 H423 R424	V313-N420 HydrophobicContact CG1-CB 3.81Å; V313-N420 VanDerWaalsContact CG1-CG 3.48Å; V313-N420 WeakPolarHBondContact CG1-OD1 3.3Å; V313-N420 HydrophobicContact CG2-CB 4.19Å; M400-N420 WeakPolarHBondContact CE-OD1 3.26Å; Q418-N420 PolarHBondContact O-N 2.94Å; Q418-N420 VanDerWaalsContact O-N 3.08Å; N420-Y422 VanDerWaalsContact C-N 3.35Å; N420-Y422 PolarHBondContact O-N 3.49Å; N420-H423 PolarHBondContact O-N 2.73Å; N420-R424 PolarHBondContact O-N 3.06Å
421	F	85.1	Confident	84.7	Confident	35 Å²	35	46.6 Å²	46.6	15%	0.154	22%	0.223	C	C	.	.	H	α-helix	trans	-61.9	-42.9	176.3	162.6	-90.8	0	0	0	110.8	F131 P132 V152 Q418 F419 H423 R424 W425	F131-F421 HydrophobicContact CB-CZ 4.14Å; F131-F421 HydrophobicContact CD1-CE1 4.15Å; F131-F421 AromaticContact CD1-CE2 3.71Å; F131-F421 HydrophobicContact CD1-CE2 3.71Å; F131-F421 AromaticContact CD1-CZ 3.18Å; F131-F421 HydrophobicContact CD1-CZ 3.18Å; F131-F421 HydrophobicContact CE1-CE2 4.38Å; F131-F421 AromaticContact CE1-CZ 3.76Å; F131-F421 HydrophobicContact CE1-CZ 3.76Å; F131-F421 AromaticContact CG-CZ 3.91Å; F131-F421 HydrophobicContact CG-CZ 3.91Å; P132-F421 HydrophobicContact CG-CD2 3.77Å; P132-F421 HydrophobicContact CG-CE2 4.32Å; P132-F421 HydrophobicContact CG-CG 4.16Å; V152-F421 HydrophobicContact CG2-CE1 3.94Å; Q418-F421 HydrophobicContact CB-CB 4.14Å; Q418-F421 VanDerWaalsContact O-CB 3.26Å; Q418-F421 WeakPolarHBondContact O-CB 3.38Å; Q418-F421 PolarHBondContact O-N 2.84Å; F419-F421 VanDerWaalsContact C-N 3.26Å; F419-F421 PolarHBondContact O-N 2.84Å; F421-H423 PolarHBondContact O-N 3.29Å; F421-R424 PolarHBondContact O-N 2.72Å; F421-W425 HydrophobicContact CE1-CB 4.35Å; F421-W425 HydrophobicContact CE2-CB 4.5Å; F421-W425 HydrophobicContact CE2-CE3 4.47Å; F421-W425 HydrophobicContact CZ-CB 4.12Å; F421-W425 HydrophobicContact CZ-CD2 4.27Å; F421-W425 HydrophobicContact CZ-CE3 4.34Å; F421-W425 HydrophobicContact CZ-CG 4.18Å; F421-W425 WeakPolarHBondContact O-CB 3.46Å; F421-W425 PolarHBondContact O-N 2.93Å
422	Y	86.3	Confident	85.3	Confident	4 Å²	4	48.9 Å²	48.9	2%	0.016	24%	0.237	C	C	.	.	H	α-helix	trans	-64.1	-38.7	179.1	-68.2	-83.2	0	0	0	113	S148 V152 V155 L396 Q418 F419 N420 F426	S148-Y422 VanDerWaalsContact C-OH 3.27Å; S148-Y422 WeakPolarHBondContact CA-OH 3.49Å; S148-Y422 WeakPolarHBondContact CB-OH 3.26Å; S148-Y422 PolarHBondContact O-OH 2.88Å; V152-Y422 HydrophobicContact CG2-CE1 3.92Å; V155-Y422 HydrophobicContact CG2-CD1 3.99Å; L396-Y422 HydrophobicContact CD1-CE1 4.33Å; Q418-Y422 WeakPolarHBondContact O-CD2 2.96Å; F419-Y422 PolarHBondContact O-N 2.81Å; N420-Y422 VanDerWaalsContact C-N 3.35Å; N420-Y422 PolarHBondContact O-N 3.49Å; Y422-F426 WeakPolarHBondContact O-CB 3.43Å; Y422-F426 PolarHBondContact O-N 2.91Å
423	H	83.7	Confident	85.8	Confident	60 Å²	60	43.4 Å²	43.4	28%	0.278	21%	0.212	S	C	.	.	H	α-helix	trans	-66.8	-46.6	175.5	-86.6	-75.7	0	0	0	112.4	M400 F419 N420 F421 W425 F426 D427	M400-H423 WeakPolarHBondContact CB-NE2 3.29Å; M400-H423 WeakPolarHBondContact CG-NE2 3.28Å; F419-H423 PolarHBondContact O-N 2.95Å; N420-H423 PolarHBondContact O-N 2.73Å; F421-H423 PolarHBondContact O-N 3.29Å; H423-W425 VanDerWaalsContact C-N 3.3Å; H423-W425 PolarHBondContact O-N 3.29Å; H423-F426 WeakPolarHBondContact O-CB 3.3Å; H423-F426 PolarHBondContact O-N 3.44Å; H423-D427 PolarHBondContact O-N 2.78Å
424	R	87.2	Confident	86.4	Confident	116 Å²	116	42.7 Å²	42.7	44%	0.438	21%	0.208	S	C	.	.	H	α-helix	trans	-62.1	-42.1	175.9	-179.1	172.7	169.2	172.5	-5.4	111.1	D311 N420 F421 F426 D427 V428	D311-R424 IonicContact OD1-CZ 3.36Å; D311-R424 IonicContact OD1-NE 3.29Å; D311-R424 IonicContact OD1-NH1 3.44Å; D311-R424 PolarHBondContact OD1-NH1 2.91Å; D311-R424 IonicContact OD2-NH1 2.7Å; D311-R424 PolarHBondContact OD2-NH1 3.31Å; N420-R424 PolarHBondContact O-N 3.06Å; F421-R424 PolarHBondContact O-N 2.72Å; R424-F426 VanDerWaalsContact C-N 3.35Å; R424-D427 PolarHBondContact O-N 3.18Å; R424-V428 VanDerWaalsContact O-CG2 3.3Å; R424-V428 WeakPolarHBondContact O-CG2 3.26Å; R424-V428 PolarHBondContact O-N 3.3Å
425	W	90.7	Very high	87	Confident	64 Å²	64	47 Å²	47	24%	0.242	23%	0.231	C	C	.	.	H	α-helix	trans	-61.5	-43.4	175.9	-173.8	-108.5	0	0	0	111.7	F131 T156 F421 H423 V428 I429	F131-W425 HydrophobicContact CE1-CD2 4.27Å; F131-W425 HydrophobicContact CE1-CE3 4.09Å; F131-W425 AromaticContact CE1-CH2 3.75Å; F131-W425 HydrophobicContact CE1-CH2 3.75Å; F131-W425 AromaticContact CE1-CZ2 3.92Å; F131-W425 HydrophobicContact CE1-CZ2 3.92Å; F131-W425 AromaticContact CE1-CZ3 3.84Å; F131-W425 HydrophobicContact CE1-CZ3 3.84Å; F131-W425 AromaticContact CZ-CH2 4Å; F131-W425 HydrophobicContact CZ-CH2 4Å; F131-W425 AromaticContact CZ-CZ2 3.89Å; F131-W425 HydrophobicContact CZ-CZ2 3.89Å; T156-W425 PolarHBondContact OG1-NE1 3.1Å; F421-W425 HydrophobicContact CE1-CB 4.35Å; F421-W425 HydrophobicContact CE2-CB 4.5Å; F421-W425 HydrophobicContact CE2-CE3 4.47Å; F421-W425 HydrophobicContact CZ-CB 4.12Å; F421-W425 HydrophobicContact CZ-CD2 4.27Å; F421-W425 HydrophobicContact CZ-CE3 4.34Å; F421-W425 HydrophobicContact CZ-CG 4.18Å; F421-W425 WeakPolarHBondContact O-CB 3.46Å; F421-W425 PolarHBondContact O-N 2.93Å; H423-W425 VanDerWaalsContact C-N 3.3Å; H423-W425 PolarHBondContact O-N 3.29Å; W425-V428 PolarHBondContact O-N 3.18Å; W425-I429 HydrophobicContact CD2-CG1 4.18Å; W425-I429 HydrophobicContact CH2-CD1 4.11Å; W425-I429 HydrophobicContact CZ2-CD1 3.76Å; W425-I429 HydrophobicContact CZ2-CG1 3.98Å; W425-I429 WeakPolarHBondContact O-CG1 3.19Å; W425-I429 PolarHBondContact O-N 2.78Å
426	F	91.3	Very high	87.9	Confident	19 Å²	19	49.7 Å²	49.7	8%	0.083	25%	0.248	C	C	.	.	H	α-helix	trans	-56	-51.7	173	-179.5	-85.6	0	0	0	111.1	V155 M158 A159 L397 Y422 H423 R424 V428 I429 F430	V155-F426 HydrophobicContact CG1-CB 3.72Å; V155-F426 HydrophobicContact CG1-CD2 4.14Å; V155-F426 HydrophobicContact CG1-CG 4.45Å; M158-F426 HydrophobicContact CB-CE2 4.38Å; M158-F426 HydrophobicContact CE-CE2 4.41Å; M158-F426 HydrophobicContact CG-CE2 3.96Å; M158-F426 HydrophobicContact SD-CE2 4.22Å; A159-F426 HydrophobicContact CB-CD2 3.67Å; A159-F426 HydrophobicContact CB-CE2 3.9Å; A159-F426 HydrophobicContact CB-CG 4.15Å; A159-F426 WeakPolarHBondContact CB-O 3.43Å; L397-F426 HydrophobicContact CD1-CD2 4.13Å; Y422-F426 WeakPolarHBondContact O-CB 3.43Å; Y422-F426 PolarHBondContact O-N 2.91Å; H423-F426 WeakPolarHBondContact O-CB 3.3Å; H423-F426 PolarHBondContact O-N 3.44Å; R424-F426 VanDerWaalsContact C-N 3.35Å; F426-V428 VanDerWaalsContact C-N 3.34Å; F426-V428 PolarHBondContact O-N 2.66Å; F426-I429 PolarHBondContact O-N 3.49Å; F426-F430 HydrophobicContact CD1-CB 4.41Å; F426-F430 HydrophobicContact CE1-CB 4.18Å; F426-F430 HydrophobicContact CE1-CD2 4.45Å; F426-F430 HydrophobicContact CE1-CG 4.41Å; F426-F430 WeakPolarHBondContact O-CB 3.46Å; F426-F430 PolarHBondContact O-N 2.93Å
427	D	91.4	Very high	89	Confident	23 Å²	23	43.2 Å²	43.2	12%	0.123	22%	0.219	C	C	.	.	H	α-helix	trans	-61.6	-41.3	-177.9	-77.4	-9.2	0	0	0	111.8	A304 N307 I308 H423 R424 L431	A304-D427 HydrophobicContact CB-CB 4.18Å; N307-D427 WeakPolarHBondContact CB-OD2 3.01Å; N307-D427 PolarHBondContact ND2-OD2 3.48Å; I308-D427 HydrophobicContact CD1-CB 4.27Å; I308-D427 HydrophobicContact CG1-CB 4.13Å; H423-D427 PolarHBondContact O-N 2.78Å; R424-D427 PolarHBondContact O-N 3.18Å; D427-L431 WeakPolarHBondContact O-CB 3.27Å; D427-L431 PolarHBondContact O-N 2.87Å
428	V	93.2	Very high	89.8	Confident	44 Å²	44	46.1 Å²	46.1	27%	0.267	23%	0.233	S	C	.	.	H	α-helix	trans	-61.9	-53.1	177.2	170.7	0	0	0	0	111.2	I308 R424 W425 F426 F430 L431 V432	I308-V428 HydrophobicContact CD1-CB 4.47Å; I308-V428 HydrophobicContact CD1-CG2 3.93Å; I308-V428 HydrophobicContact CG1-CG2 3.89Å; I308-V428 HydrophobicContact CG2-CG2 4.4Å; R424-V428 VanDerWaalsContact O-CG2 3.3Å; R424-V428 WeakPolarHBondContact O-CG2 3.26Å; R424-V428 PolarHBondContact O-N 3.3Å; W425-V428 PolarHBondContact O-N 3.18Å; F426-V428 VanDerWaalsContact C-N 3.34Å; F426-V428 PolarHBondContact O-N 2.66Å; V428-F430 VanDerWaalsContact C-N 3.32Å; V428-F430 PolarHBondContact O-N 3.4Å; V428-L431 PolarHBondContact O-N 3.43Å; V428-V432 WeakPolarHBondContact O-CG2 3.34Å; V428-V432 PolarHBondContact O-N 3.41Å
429	I	94.6	Very high	90.6	Very high	25 Å²	25	45.6 Å²	45.6	13%	0.128	23%	0.234	C	C	.	.	H	α-helix	trans	-67.1	-37.7	-178.3	-62.1	-59.8	0	0	0	111	T156 A159 L160 W425 F426 L431 V432 S433	T156-I429 HydrophobicContact CG2-CG1 4.41Å; T156-I429 HydrophobicContact CG2-CG2 4.06Å; A159-I429 HydrophobicContact CB-CB 3.7Å; A159-I429 HydrophobicContact CB-CG2 3.63Å; L160-I429 HydrophobicContact CD2-CG2 3.75Å; L160-I429 HydrophobicContact CG-CG2 3.74Å; W425-I429 HydrophobicContact CD2-CG1 4.18Å; W425-I429 HydrophobicContact CH2-CD1 4.11Å; W425-I429 HydrophobicContact CZ2-CD1 3.76Å; W425-I429 HydrophobicContact CZ2-CG1 3.98Å; W425-I429 WeakPolarHBondContact O-CG1 3.19Å; W425-I429 PolarHBondContact O-N 2.78Å; F426-I429 PolarHBondContact O-N 3.49Å; I429-L431 PolarHBondContact O-N 2.87Å; I429-V432 PolarHBondContact O-N 3.15Å; I429-S433 VanDerWaalsContact O-CB 3.24Å; I429-S433 WeakPolarHBondContact O-CB 3.36Å; I429-S433 PolarHBondContact O-N 2.81Å
430	F	94.4	Very high	91.3	Very high	0 Å²	0	51.6 Å²	51.6	0%	0	26%	0.26	C	S	.	.	H	α-helix	trans	-58.7	-47.4	174.7	170	-94	0	0	0	110.9	A159 S162 A166 K300 I301 A304 F426 V428 S433 A434	A159-F430 HydrophobicContact CB-CB 4.34Å; S162-F430 WeakPolarHBondContact O-CE2 3.37Å; A166-F430 HydrophobicContact CB-CE2 3.92Å; A166-F430 HydrophobicContact CB-CZ 3.88Å; K300-F430 HydrophobicContact CB-CZ 4.42Å; K300-F430 HydrophobicContact CD-CE1 4.28Å; K300-F430 HydrophobicContact CD-CE2 4.05Å; K300-F430 HydrophobicContact CD-CZ 3.66Å; K300-F430 HydrophobicContact CG-CE1 3.96Å; K300-F430 HydrophobicContact CG-CZ 3.8Å; I301-F430 HydrophobicContact CG1-CE1 4Å; I301-F430 HydrophobicContact CG1-CZ 4.29Å; A304-F430 HydrophobicContact CB-CD1 4.03Å; A304-F430 HydrophobicContact CB-CE1 4.34Å; F426-F430 HydrophobicContact CD1-CB 4.41Å; F426-F430 HydrophobicContact CE1-CB 4.18Å; F426-F430 HydrophobicContact CE1-CD2 4.45Å; F426-F430 HydrophobicContact CE1-CG 4.41Å; F426-F430 WeakPolarHBondContact O-CB 3.46Å; F426-F430 PolarHBondContact O-N 2.93Å; V428-F430 VanDerWaalsContact C-N 3.32Å; V428-F430 PolarHBondContact O-N 3.4Å; F430-S433 PolarHBondContact O-N 3.12Å; F430-A434 WeakPolarHBondContact O-CB 3.28Å; F430-A434 PolarHBondContact O-N 3.38Å
431	L	94.9	Very high	91.6	Very high	28 Å²	28	49 Å²	49	15%	0.147	25%	0.246	C	C	.	.	H	α-helix	trans	-64.1	-47	179.5	-176.8	63.9	0	0	0	111.5	I301 I308 D427 V428 I429 S433 A434 L435	I301-L431 HydrophobicContact CG2-CD1 3.84Å; I308-L431 HydrophobicContact CD1-CB 4.25Å; I308-L431 HydrophobicContact CD1-CD2 3.77Å; D427-L431 WeakPolarHBondContact O-CB 3.27Å; D427-L431 PolarHBondContact O-N 2.87Å; V428-L431 PolarHBondContact O-N 3.43Å; I429-L431 PolarHBondContact O-N 2.87Å; L431-S433 VanDerWaalsContact C-N 3.29Å; L431-S433 PolarHBondContact O-N 2.76Å; L431-A434 PolarHBondContact O-N 3.36Å; L431-L435 HydrophobicContact CD1-CD1 4.08Å; L431-L435 HydrophobicContact CD1-CG 4.13Å; L431-L435 HydrophobicContact CG-CD1 3.96Å; L431-L435 HydrophobicContact CG-CG 4.39Å; L431-L435 WeakPolarHBondContact O-CB 3.36Å; L431-L435 VanDerWaalsContact O-CG 3.3Å; L431-L435 WeakPolarHBondContact O-CG 3.45Å; L431-L435 PolarHBondContact O-N 2.84Å
432	V	95.9	Very high	91.7	Very high	89 Å²	89	54.5 Å²	54.5	54%	0.539	27%	0.267	S	S	.	.	H	α-helix	trans	-59.4	-42	176.4	172.2	0	0	0	0	111	V428 I429 S436	V428-V432 WeakPolarHBondContact O-CG2 3.34Å; V428-V432 PolarHBondContact O-N 3.41Å; I429-V432 PolarHBondContact O-N 3.15Å; V432-S436 VanDerWaalsContact O-CB 3.29Å; V432-S436 WeakPolarHBondContact O-CB 3.35Å; V432-S436 PolarHBondContact O-N 3.03Å; V432-S436 PolarHBondContact O-OG 3.23Å
433	S	95.5	Very high	91.8	Very high	8 Å²	8	58.4 Å²	58.4	6%	0.056	29%	0.287	C	S	.	.	H	α-helix	trans	-66.6	-43.4	177	179.3	0	0	0	0	112.8	L160 F164 I429 F430 L431 S436 S437	L160-S433 PolarHBondContact O-OG 2.9Å; F164-S433 PolarHBondContact N-OG 2.87Å; I429-S433 VanDerWaalsContact O-CB 3.24Å; I429-S433 WeakPolarHBondContact O-CB 3.36Å; I429-S433 PolarHBondContact O-N 2.81Å; F430-S433 PolarHBondContact O-N 3.12Å; L431-S433 VanDerWaalsContact C-N 3.29Å; L431-S433 PolarHBondContact O-N 2.76Å; S433-S436 WeakPolarHBondContact CA-OG 3.3Å; S433-S436 PolarHBondContact O-OG 3.2Å; S433-S437 VanDerWaalsContact O-CB 3.3Å; S433-S437 WeakPolarHBondContact O-CB 3.11Å; S433-S437 PolarHBondContact O-OG 3.49Å; S433-S437 PolarHBondContact O-N 3.39Å
434	A	93.5	Very high	91.8	Very high	0 Å²	0	57.3 Å²	57.3	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-64.9	-47.3	178	0	0	0	0	0	111.2	V167 I301 F430 L431 S437 I438	V167-A434 HydrophobicContact CG2-CB 4.06Å; V167-A434 WeakPolarHBondContact CG2-O 3.19Å; I301-A434 HydrophobicContact CD1-CB 3.99Å; I301-A434 HydrophobicContact CG1-CB 4.15Å; F430-A434 WeakPolarHBondContact O-CB 3.28Å; F430-A434 PolarHBondContact O-N 3.38Å; L431-A434 PolarHBondContact O-N 3.36Å; A434-S437 PolarHBondContact O-N 2.95Å; A434-I438 VanDerWaalsContact O-CG1 3.3Å; A434-I438 WeakPolarHBondContact O-CG1 3.46Å; A434-I438 PolarHBondContact O-N 3.33Å
435	L	95.1	Very high	91.4	Very high	94 Å²	94	55.2 Å²	55.2	49%	0.492	28%	0.284	S	S	.	.	H	α-helix	trans	-64.1	-42.8	179	-68.6	176.1	0	0	0	112.3	L431 S437 I438 L439	L431-L435 HydrophobicContact CD1-CD1 4.08Å; L431-L435 HydrophobicContact CD1-CG 4.13Å; L431-L435 HydrophobicContact CG-CD1 3.96Å; L431-L435 HydrophobicContact CG-CG 4.39Å; L431-L435 WeakPolarHBondContact O-CB 3.36Å; L431-L435 VanDerWaalsContact O-CG 3.3Å; L431-L435 WeakPolarHBondContact O-CG 3.45Å; L431-L435 PolarHBondContact O-N 2.84Å; L435-S437 VanDerWaalsContact C-N 3.32Å; L435-S437 PolarHBondContact O-N 2.96Å; L435-I438 PolarHBondContact O-N 3.07Å; L435-L439 WeakPolarHBondContact O-CB 3.36Å; L435-L439 PolarHBondContact O-N 3.08Å
436	S	94.9	Very high	90.8	Very high	64 Å²	64	59.8 Å²	59.8	45%	0.448	31%	0.306	S	S	.	.	H	α-helix	trans	-65.3	-36.2	175.8	57.6	0	0	0	0	112.1	V432 S433 L439 F440	V432-S436 VanDerWaalsContact O-CB 3.29Å; V432-S436 WeakPolarHBondContact O-CB 3.35Å; V432-S436 PolarHBondContact O-N 3.03Å; V432-S436 PolarHBondContact O-OG 3.23Å; S433-S436 WeakPolarHBondContact CA-OG 3.3Å; S433-S436 PolarHBondContact O-OG 3.2Å; S436-L439 PolarHBondContact O-N 3.31Å; S436-F440 WeakPolarHBondContact O-CB 3.24Å; S436-F440 PolarHBondContact O-N 2.94Å
437	S	92.2	Very high	89.9	Confident	12 Å²	12	66.7 Å²	66.7	8%	0.084	34%	0.338	C	S	.	.	H	α-helix	trans	-67.7	-41	174.4	-57.8	0	0	0	0	112.4	S433 A434 L435 F440 L441	S433-S437 VanDerWaalsContact O-CB 3.3Å; S433-S437 WeakPolarHBondContact O-CB 3.11Å; S433-S437 PolarHBondContact O-OG 3.49Å; S433-S437 PolarHBondContact O-N 3.39Å; A434-S437 PolarHBondContact O-N 2.95Å; L435-S437 VanDerWaalsContact C-N 3.32Å; L435-S437 PolarHBondContact O-N 2.96Å; S437-F440 PolarHBondContact O-N 3.37Å; S437-L441 WeakPolarHBondContact O-CG 3.39Å; S437-L441 PolarHBondContact O-N 3.19Å
438	I	92.2	Very high	88.5	Confident	75 Å²	75	67 Å²	67	39%	0.385	34%	0.344	S	S	.	.	H	α-helix	trans	-61	-47.4	173.6	-70.1	163.3	0	0	0	110	V167 I301 A434 L435 F440 L441 Y442	V167-I438 HydrophobicContact CB-CG1 4.38Å; V167-I438 HydrophobicContact CG1-CG1 3.64Å; V167-I438 HydrophobicContact CG2-CD1 4.21Å; V167-I438 HydrophobicContact CG2-CG1 3.74Å; I301-I438 HydrophobicContact CD1-CD1 4.32Å; A434-I438 VanDerWaalsContact O-CG1 3.3Å; A434-I438 WeakPolarHBondContact O-CG1 3.46Å; A434-I438 PolarHBondContact O-N 3.33Å; L435-I438 PolarHBondContact O-N 3.07Å; I438-F440 VanDerWaalsContact C-N 3.35Å; I438-F440 PolarHBondContact O-N 3.18Å; I438-L441 PolarHBondContact O-N 3.12Å; I438-Y442 VanDerWaalsContact O-CB 3.3Å; I438-Y442 WeakPolarHBondContact O-CB 3.39Å; I438-Y442 PolarHBondContact O-N 3.48Å
439	L	93.2	Very high	86.6	Confident	100 Å²	100	66.9 Å²	66.9	52%	0.524	34%	0.344	S	S	.	.	H	α-helix	trans	-60.6	-44.9	178	178.5	62.5	0	0	0	111.4	L435 S436 Y442 L443	L435-L439 WeakPolarHBondContact O-CB 3.36Å; L435-L439 PolarHBondContact O-N 3.08Å; S436-L439 PolarHBondContact O-N 3.31Å; L439-Y442 PolarHBondContact O-N 3.47Å; L439-L443 PolarHBondContact O-N 3.02Å; L439-L443 WeakPolarHBondContact O-CG 3.41Å; L439-L443 VanDerWaalsContact O-CG 3.31Å; L439-L443 HydrophobicContact CD1-CG 4.26Å; L439-L443 HydrophobicContact CD1-CD1 4.24Å; L439-L443 HydrophobicContact CG-CD1 4.19Å
440	F	91.4	Very high	84.7	Confident	140 Å²	140	70.3 Å²	70.3	61%	0.614	36%	0.36	S	S	*	.	H	α-helix	trans	-59.9	-49.3	177.4	178	-96.1	0	0	0	111.7	S436 S437 I438 Y442 L443 A444	S436-F440 WeakPolarHBondContact O-CB 3.24Å; S436-F440 PolarHBondContact O-N 2.94Å; S437-F440 PolarHBondContact O-N 3.37Å; I438-F440 VanDerWaalsContact C-N 3.35Å; I438-F440 PolarHBondContact O-N 3.18Å; F440-Y442 VanDerWaalsContact C-N 3.34Å; F440-Y442 PolarHBondContact O-N 2.86Å; F440-L443 PolarHBondContact O-N 2.73Å; F440-A444 WeakPolarHBondContact O-CB 3.45Å; F440-A444 PolarHBondContact O-N 3.5Å
441	L	86.8	Confident	82.3	Confident	29 Å²	29	80 Å²	80	15%	0.152	40%	0.401	C	S	.	.	H	α-helix	trans	-64	-38.7	177.8	-71.6	175.8	0	0	0	112.1	V167 Y171 S437 I438 A444 H445	V167-L441 HydrophobicContact CG1-CD1 3.6Å; Y171-L441 HydrophobicContact CD1-CD1 4.18Å; Y171-L441 HydrophobicContact CD1-CD2 3.86Å; Y171-L441 HydrophobicContact CD2-CD1 4.06Å; Y171-L441 HydrophobicContact CD2-CD2 4.4Å; Y171-L441 HydrophobicContact CE1-CD2 3.74Å; Y171-L441 HydrophobicContact CE2-CD2 4.3Å; Y171-L441 HydrophobicContact CG-CD1 3.79Å; Y171-L441 HydrophobicContact CG-CD2 4.2Å; S437-L441 WeakPolarHBondContact O-CG 3.39Å; S437-L441 PolarHBondContact O-N 3.19Å; I438-L441 PolarHBondContact O-N 3.12Å; L441-A444 PolarHBondContact O-N 2.91Å; L441-H445 WeakPolarHBondContact O-CB 3.46Å; L441-H445 PolarHBondContact O-N 2.77Å
442	Y	87.7	Confident	79.7	Confident	150 Å²	150	87 Å²	87	59%	0.588	43%	0.434	S	S	*	.	H	α-helix	trans	-61.9	-44.8	175.7	176	-102.4	0	0	0	112.1	I438 L439 F440 H445 K446	I438-Y442 VanDerWaalsContact O-CB 3.3Å; I438-Y442 WeakPolarHBondContact O-CB 3.39Å; I438-Y442 PolarHBondContact O-N 3.48Å; L439-Y442 PolarHBondContact O-N 3.47Å; F440-Y442 VanDerWaalsContact C-N 3.34Å; F440-Y442 PolarHBondContact O-N 2.86Å; Y442-H445 PolarHBondContact O-N 3.11Å; Y442-K446 PolarHBondContact O-N 3.4Å
443	L	89	Confident	77	Confident	86 Å²	86	89.1 Å²	89.1	45%	0.45	44%	0.439	S	S	.	.	H	α-helix	trans	-65.9	-42.3	176.1	-69	175.2	0	0	0	111.8	L439 F440 H445 K446 Q447	L439-L443 PolarHBondContact O-N 3.02Å; L439-L443 WeakPolarHBondContact O-CG 3.41Å; L439-L443 VanDerWaalsContact O-CG 3.31Å; L439-L443 HydrophobicContact CD1-CG 4.26Å; L439-L443 HydrophobicContact CD1-CD1 4.24Å; L439-L443 HydrophobicContact CG-CD1 4.19Å; F440-L443 PolarHBondContact O-N 2.73Å; L443-H445 PolarHBondContact O-N 3.13Å; L443-H445 VanDerWaalsContact C-N 3.33Å; L443-K446 PolarHBondContact O-N 2.97Å; L443-Q447 WeakPolarHBondContact O-CG 3.18Å; L443-Q447 PolarHBondContact O-N 3.36Å; L443-Q447 VanDerWaalsContact O-N 3.09Å
444	A	83.3	Confident	74	Confident	38 Å²	38	92.7 Å²	92.7	31%	0.314	47%	0.469	S	S	.	.	H	α-helix	trans	-61.3	-41.7	176.6	0	0	0	0	0	111.7	F440 L441 Q447 A448	F440-A444 WeakPolarHBondContact O-CB 3.45Å; F440-A444 PolarHBondContact O-N 3.5Å; L441-A444 PolarHBondContact O-N 2.91Å; A444-Q447 PolarHBondContact O-N 2.91Å; A444-A448 PolarHBondContact O-N 2.83Å
445	H	78	Confident	71.2	Confident	71 Å²	71	102.3 Å²	102.3	33%	0.329	53%	0.532	S	S	.	.	H	α-helix	trans	-69.3	-34.3	177.9	-145.1	63.4	0	0	0	112.4	L441 Y442 L443 Q447 A448	L441-H445 WeakPolarHBondContact O-CB 3.46Å; L441-H445 PolarHBondContact O-N 2.77Å; Y442-H445 PolarHBondContact O-N 3.11Å; L443-H445 PolarHBondContact O-N 3.13Å; L443-H445 VanDerWaalsContact C-N 3.33Å; H445-Q447 VanDerWaalsContact C-N 3.3Å; H445-Q447 PolarHBondContact O-N 3.32Å; H445-A448 WeakPolarHBondContact O-CB 3.21Å; H445-A448 PolarHBondContact O-N 2.99Å
446	K	78.8	Confident	70	Confident	160 Å²	160	102.8 Å²	102.8	70%	0.696	53%	0.534	S	S	*	.	H	α-helix	trans	-67.8	-30.2	174.7	-170.4	179.3	178	-176.3	0	112.9	Y442 L443	Y442-K446 PolarHBondContact O-N 3.4Å; L443-K446 PolarHBondContact O-N 2.97Å
447	Q	71.1	Confident	68.7	Low	165 Å²	165	104.8 Å²	104.8	77%	0.771	54%	0.539	S	S	*	.	H	α-helix	trans	-80.4	-16.1	176	-71.9	179	-20.7	0	0	113	L443 A444 H445	L443-Q447 WeakPolarHBondContact O-CG 3.18Å; L443-Q447 PolarHBondContact O-N 3.36Å; L443-Q447 VanDerWaalsContact O-N 3.09Å; A444-Q447 PolarHBondContact O-N 2.91Å; H445-Q447 VanDerWaalsContact C-N 3.3Å; H445-Q447 PolarHBondContact O-N 3.32Å
448	A	62.8	Low	67.4	Low	29 Å²	29	109.9 Å²	109.9	24%	0.24	56%	0.564	C	S	.	*	S	Bend	trans	-63.8	129.5	174.1	0	0	0	0	0	109.5	A444 H445 E450	A444-A448 PolarHBondContact O-N 2.83Å; H445-A448 WeakPolarHBondContact O-CB 3.21Å; H445-A448 PolarHBondContact O-N 2.99Å; A448-E450 PolarHBondContact O-N 2.75Å
449	P	54.2	Low	65.9	Low	42 Å²	42	112 Å²	112	27%	0.273	57%	0.574	S	S	.	*			trans	-71.4	32.5	-171.5	26.9	-34.4	0	0	0	115.2	K451 Q452	P449-K451 PolarHBondContact O-N 3.03Å; P449-Q452 PolarHBondContact O-N 3.2Å
450	E	53.4	Low	64.2	Low	97 Å²	97	112.8 Å²	112.8	45%	0.453	58%	0.577	S	S	.	*	T	Hydrogen-bonded Turn	trans	-66	-1.8	-179.1	-72.9	-168.9	160.6	0	0	114.5	R179 A448	R179-E450 WeakPolarHBondContact CB-OE1 3.15Å; R179-E450 HydrophobicContact CG-CG 4.42Å; R179-E450 WeakPolarHBondContact CG-OE1 2.98Å; A448-E450 PolarHBondContact O-N 2.75Å
451	K	43.7	Very low	62.4	Low	202 Å²	202	110.9 Å²	110.9	88%	0.878	58%	0.575	S	S	*	*	T	Hydrogen-bonded Turn	trans	-115	8.6	179.4	-76.6	-171.2	175.7	-175	0	116.1	P449	P449-K451 PolarHBondContact O-N 3.03Å
452	Q	41.9	Very low	60.6	Low	176 Å²	176	116.8 Å²	116.8	82%	0.822	61%	0.605	S	S	*	*	S	Bend	trans	-113.4	7.8	177.8	-70.7	-172.1	-16.4	0	0	114.6	P449	P449-Q452 PolarHBondContact O-N 3.2Å
453	M	39.3	Very low	58.6	Low	133 Å²	133	114.2 Å²	114.2	66%	0.655	61%	0.607	S	S	*	*	S	Bend	trans	-126.6	14.7	-177.8	-64.9	-175.8	-174	0	0	114.8
454	A	30.8	Very low	56	Low	83 Å²	83	116.6 Å²	116.6	69%	0.686	62%	0.62	S	S	*	*			trans	-97.7	127.8	161	0	0	0	0	0	107.9
455	P	35.1	Very low	53.5	Low	203 Å²	203	123.7 Å²	123.7	100%	1.318	65%	0.647	S	S	*	*			trans	-59.8	0	172.3	26.2	-33.1	0	0	0	112.4

Retrieved 455 of 455 residues in 92.6 ms (Link to these results)

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