F7GPZ7_MACMU Loading...

5'-nucleotidase

AlphaFold DB , UniProt , Accession F7GPZ7, Species MACMU (Macaca mulatta, Rhesus macaque), Gene NT5E, Length 574 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M42.4Very low42.3Very low254 Ų254151.4 Ų151.4100%1.25189%0.886SS**  0100.40-78.4167.1147.400107.6
2C36.7Very low42.3Very low128 Ų128151.6 Ų151.687%0.86588%0.879SS**  trans-107.3153.3-178.5-1090000110.1
3P48.8Very low42.3Very low124 Ų124152.7 Ų152.781%0.80588%0.878SS**PPolyproline II helixtrans-82.3154-165.233.2-33.4000113.6
4R40.7Very low42.4Very low255 Ų255152.1 Ų152.196%0.96287%0.87SS**PPolyproline II helixtrans-72.6132.1-179.2-77175.2170172.8-3.9111.8
5A42Very low42.6Very low100 Ų100148.3 Ų148.383%0.82686%0.864SS**PPolyproline II helixtrans-84.5139.6171.400000111.8
6A43.4Very low42.8Very low105 Ų105146.8 Ų146.887%0.86886%0.857SS**PPolyproline II helixtrans-75.1141.6175.800000111.8
7R41.8Very low43Very low248 Ų248142.1 Ų142.194%0.93685%0.847SS**  trans-106.2127.7169.6-78.2-176.9174.4-179.6-2.3109.6
8A41.4Very low43Very low93 Ų93138.7 Ų138.777%0.76984%0.837SS**  trans-77.8154.6167.600000110.9
9P46.3Very low43.1Very low123 Ų123140.2 Ų140.280%0.79984%0.839SS**  trans-83.4134.3175.233.1-29000110.4
10A41.4Very low43Very low104 Ų104141.5 Ų141.586%0.8684%0.841SS**  trans-82.2114.8170.100000109.2L12A10-L12 PolarHBondContact O-N 3.41Å
11T40.4Very low42.9Very low131 Ų131146.2 Ų146.280%0.80484%0.844SS**  trans-76.3110.9170.9-90000108.8L13T11-L13 PolarHBondContact O-N 3.23Å
12L42.5Very low42.8Very low154 Ų154138.8 Ų138.881%0.80682%0.817SS**  trans-81.7103.3174-160.580.6000108.5A10 L14A10-L12 PolarHBondContact O-N 3.41Å; L12-L14 PolarHBondContact O-N 3.39Å
13L42.5Very low43.3Very low166 Ų166137.3 Ų137.387%0.86981%0.814SS**  trans-73.2104.6168.5-101111.9000109T11 A15T11-L13 PolarHBondContact O-N 3.23Å; L13-A15 PolarHBondContact O-N 3.09Å
14L43.9Very low43.6Very low145 Ų145134.2 Ų134.276%0.75980%0.799SS**  trans-7499.7162.6-101.5132.6000108.3L12 V16L12-L14 PolarHBondContact O-N 3.39Å; L14-V16 PolarHBondContact O-N 3.25Å; L14-V16 VanDerWaalsContact O-N 3.09Å
15A44.3Very low44.9Very low94 Ų94124.9 Ų124.978%0.77778%0.782SS**  trans-70.996.9165.800000108.6L13 G17L13-A15 PolarHBondContact O-N 3.09Å; A15-G17 VanDerWaalsContact C-N 3.31Å; A15-G17 PolarHBondContact O-N 2.94Å
16V47Very low47.2Very low125 Ų125123 Ų12376%0.75877%0.767SS**  trans-71.992.5165.8178.90000106.8L14 A18L14-V16 PolarHBondContact O-N 3.25Å; L14-V16 VanDerWaalsContact O-N 3.09Å; V16-A18 VanDerWaalsContact C-N 3.26Å; V16-A18 PolarHBondContact O-N 3.03Å
17G45.2Very low49.7Very low67 Ų67119.8 Ų119.869%0.69173%0.732SS**  trans-66.589.8164.800000108.5A15 L19A15-G17 VanDerWaalsContact C-N 3.31Å; A15-G17 PolarHBondContact O-N 2.94Å; G17-L19 VanDerWaalsContact C-N 3.27Å; G17-L19 PolarHBondContact O-N 2.84Å
18A43.3Very low52.4Low80 Ų80110.5 Ų110.566%0.66170%0.699SS**  trans-62.796.8162.900000107V16 L20V16-A18 VanDerWaalsContact C-N 3.26Å; V16-A18 PolarHBondContact O-N 3.03Å; A18-L20 PolarHBondContact O-N 2.99Å
19L44.5Very low55.1Low168 Ų168106.1 Ų106.188%0.8866%0.663SS**  trans-58.390.7157-86147000106.2G17 W21G17-L19 VanDerWaalsContact C-N 3.27Å; G17-L19 PolarHBondContact O-N 2.84Å; L19-W21 PolarHBondContact O-N 2.91Å
20L40.9Very low57.7Low166 Ų166100.3 Ų100.387%0.86963%0.625SS**  trans-6284.5156.7-76.6161.1000105.6A18 S22A18-L20 PolarHBondContact O-N 2.99Å; L20-S22 PolarHBondContact O-N 2.96Å
21W41.2Very low60.4Low241 Ų24195.4 Ų95.491%0.91358%0.584SS**  trans-61.8101.1157.4-142.5-37.3000103.8L19 A23L19-W21 PolarHBondContact O-N 2.91Å; W21-A23 PolarHBondContact O-N 2.83Å
22S41.2Very low63.2Low98 Ų9889.1 Ų89.169%0.68555%0.546SS*.  trans-51.3116.3166.146.60000105.6L20 A24L20-S22 PolarHBondContact O-N 2.96Å; S22-A24 VanDerWaalsContact C-N 3.33Å; S22-A24 PolarHBondContact O-N 2.96Å
23A45.7Very low65.9Low97 Ų9781.8 Ų81.880%0.80251%0.508SS*.  trans-54.2109.216600000105.6W21 G25W21-A23 PolarHBondContact O-N 2.83Å; A23-G25 PolarHBondContact O-N 2.86Å
24A55.7Low68.6Low59 Ų5974 Ų7449%0.48847%0.467SS..  trans-43.5108173.100000108.8S22 E296S22-A24 VanDerWaalsContact C-N 3.33Å; S22-A24 PolarHBondContact O-N 2.96Å; A24-E296 HydrophobicContact CB-CG 3.98Å; A24-E296 WeakPolarHBondContact CB-OE1 3.48Å
25G68.7Low71.2Confident59 Ų5967.2 Ų67.261%0.60843%0.431SS*.PPolyproline II helixtrans-73136.3-173.700000110.5A23A23-G25 PolarHBondContact O-N 2.86Å
26A89.1Confident73.6Confident61 Ų6162.8 Ų62.850%0.50440%0.395SS..PPolyproline II helixtrans-58.5139.6168.800000110F294 I301A26-F294 WeakPolarHBondContact CA-O 3.38Å; A26-I301 HydrophobicContact CB-CD1 4.04Å
27W97.3Very high76Confident37 Ų3757.4 Ų57.414%0.1436%0.362CS..EExtended strand (participates in β ladder)trans-98.4122176.1-17784.2000109.8L29 N77 V166 E169 V171 K214 F294W27-L29 HydrophobicContact CE3-CB 4.27Å; W27-L29 HydrophobicContact CH2-CB 3.89Å; W27-L29 HydrophobicContact CH2-CD1 3.93Å; W27-L29 HydrophobicContact CH2-CD2 4.34Å; W27-L29 HydrophobicContact CH2-CG 4.26Å; W27-L29 HydrophobicContact CZ3-CB 3.58Å; W27-L29 HydrophobicContact CZ3-CD1 4.45Å; W27-L29 HydrophobicContact CZ3-CD2 4.21Å; W27-L29 HydrophobicContact CZ3-CG 4.29Å; W27-N77 HydrophobicContact CZ2-CB 4.03Å; W27-N77 PolarHBondContact NE1-ND2 2.77Å; W27-N77 VanDerWaalsContact NE1-ND2 3.17Å; W27-V166 HydrophobicContact CH2-CB 4.12Å; W27-V166 HydrophobicContact CH2-CG1 4.1Å; W27-V166 HydrophobicContact CZ2-CB 3.94Å; W27-V166 HydrophobicContact CZ2-CG1 3.82Å; W27-V166 WeakPolarHBondContact CZ2-O 2.95Å; W27-E169 HydrophobicContact CD2-CB 4.37Å; W27-E169 HydrophobicContact CD2-CG 3.98Å; W27-E169 HydrophobicContact CG-CG 4Å; W27-E169 HydrophobicContact CH2-CB 4.38Å; W27-E169 HydrophobicContact CZ2-CB 3.83Å; W27-E169 HydrophobicContact CZ2-CG 4.27Å; W27-V171 HydrophobicContact CH2-CG2 3.76Å; W27-V171 HydrophobicContact CZ3-CG2 4.19Å; W27-K214 HydrophobicContact CE3-CD 3.59Å; W27-K214 HydrophobicContact CZ3-CD 3.57Å; W27-F294 HydrophobicContact CE3-CB 4.43Å; W27-F294 AromaticContact CE3-CD2 3.83Å; W27-F294 HydrophobicContact CE3-CD2 3.83Å; W27-F294 HydrophobicContact CE3-CG 4.49Å; W27-F294 HydrophobicContact CZ3-CD2 4Å; W27-F294 HydrophobicContact CZ3-CE2 4.35Å; W27-F294 PolarHBondContact N-O 2.91Å; W27-F294 PolarHBondContact O-N 3.47Å
28E98.2Very high78.3Confident53 Ų5354.5 Ų54.525%0.24833%0.331CS..EExtended strand (participates in β ladder)trans-98134.6-177.4-167.3-178.860.300111.3N77 K291 I292 E293E28-N77 VanDerWaalsContact O-CB 3.26Å; E28-N77 WeakPolarHBondContact O-CB 3.41Å; E28-N77 PolarHBondContact O-ND2 2.93Å; E28-K291 VanDerWaalsContact OE1-CE 3.22Å; E28-K291 WeakPolarHBondContact OE1-CE 3.47Å; E28-K291 IonicContact OE1-NZ 3.84Å; E28-K291 PolarHBondContact OE1-NZ 3.27Å; E28-K291 WeakPolarHBondContact OE2-CE 3.23Å; E28-K291 IonicContact OE2-NZ 3.86Å; E28-K291 PolarHBondContact OE2-NZ 3.17Å; E28-I292 CarbonylContact C-O 3.17Å; E28-I292 WeakPolarHBondContact CA-O 3.37Å; E28-E293 HydrophobicContact CG-CG 4.45Å
29L98.8Very high80.8Confident0 Ų050.7 Ų50.70%030%0.299CS..EExtended strand (participates in β ladder)trans-121.1131.5172.717763.2000110.2W27 I31 N77 L79 V166 V171 I216 K291 I292 F294W27-L29 HydrophobicContact CE3-CB 4.27Å; W27-L29 HydrophobicContact CH2-CB 3.89Å; W27-L29 HydrophobicContact CH2-CD1 3.93Å; W27-L29 HydrophobicContact CH2-CD2 4.34Å; W27-L29 HydrophobicContact CH2-CG 4.26Å; W27-L29 HydrophobicContact CZ3-CB 3.58Å; W27-L29 HydrophobicContact CZ3-CD1 4.45Å; W27-L29 HydrophobicContact CZ3-CD2 4.21Å; W27-L29 HydrophobicContact CZ3-CG 4.29Å; L29-I31 HydrophobicContact CD2-CD1 4.18Å; L29-I31 HydrophobicContact CD2-CG1 3.86Å; L29-I31 HydrophobicContact CG-CG1 3.98Å; L29-N77 HydrophobicContact CD1-CB 4.41Å; L29-L79 HydrophobicContact CD1-CD1 4.17Å; L29-L79 HydrophobicContact CD1-CG 4.14Å; L29-L79 HydrophobicContact CD2-CD1 4.27Å; L29-V166 HydrophobicContact CD1-CG1 4.08Å; L29-V171 HydrophobicContact CD2-CG2 4.28Å; L29-I216 HydrophobicContact CD2-CD1 4.2Å; L29-K291 WeakPolarHBondContact O-CA 3.43Å; L29-I292 PolarHBondContact N-O 3.24Å; L29-I292 PolarHBondContact O-N 2.93Å; L29-F294 HydrophobicContact CB-CE2 4.28Å; L29-F294 HydrophobicContact CD2-CE2 4.29Å
30T98.9Very high83.2Confident2 Ų243.4 Ų43.41%0.01226%0.26CS..EExtended strand (participates in β ladder)trans-98.9115.4166.9-62.40000109.8L32 I71 E75 N77 V78 L79 Y289 L290T30-L32 HydrophobicContact CG2-CD2 4.05Å; T30-L32 HydrophobicContact CG2-CG 4.4Å; T30-I71 HydrophobicContact CG2-CG2 4.03Å; T30-E75 HydrophobicContact CG2-CG 4.49Å; T30-N77 PolarHBondContact N-O 3.01Å; T30-V78 WeakPolarHBondContact O-CA 3.48Å; T30-L79 PolarHBondContact O-N 3.45Å; T30-Y289 HydrophobicContact CG2-CD2 3.83Å; T30-Y289 HydrophobicContact CG2-CE2 3.52Å; T30-L290 WeakPolarHBondContact CA-O 3.45Å
31I98.9Very high85.9Confident0 Ų035.9 Ų35.90%022%0.22CC..EExtended strand (participates in β ladder)trans-95.6112.9171.6-55.3176.2000108.2L29 L81 I216 V238 V240 L290 I292L29-I31 HydrophobicContact CD2-CD1 4.18Å; L29-I31 HydrophobicContact CD2-CG1 3.86Å; L29-I31 HydrophobicContact CG-CG1 3.98Å; I31-L81 HydrophobicContact CG2-CD1 3.9Å; I31-L81 HydrophobicContact CG2-CG 4.37Å; I31-I216 HydrophobicContact CD1-CD1 3.68Å; I31-I216 HydrophobicContact CD1-CG1 4.26Å; I31-I216 HydrophobicContact CG1-CD1 4.28Å; I31-V238 HydrophobicContact CD1-CG1 4.04Å; I31-V238 HydrophobicContact CD1-CG2 4.38Å; I31-V240 HydrophobicContact CG2-CG2 4.14Å; I31-L290 HydrophobicContact CB-CB 4.45Å; I31-L290 PolarHBondContact N-O 2.83Å; I31-L290 PolarHBondContact O-N 3.13Å; I31-I292 HydrophobicContact CD1-CD1 3.59Å; I31-I292 HydrophobicContact CG1-CD1 4.44Å
32L98.9Very high88.6Confident0 Ų026.9 Ų26.90%019%0.189CC..EExtended strand (participates in β ladder)trans-90.7134.3163.6-58.2-175.8000108.5T30 V68 I71 V78 L79 L80 L81 L287 G288 Y289T30-L32 HydrophobicContact CG2-CD2 4.05Å; T30-L32 HydrophobicContact CG2-CG 4.4Å; L32-V68 HydrophobicContact CD1-CB 4.46Å; L32-V68 HydrophobicContact CD1-CG1 4.28Å; L32-V68 HydrophobicContact CD1-CG2 4.25Å; L32-I71 HydrophobicContact CD1-CB 4.22Å; L32-I71 HydrophobicContact CD1-CD1 4.3Å; L32-I71 HydrophobicContact CD1-CG2 4.17Å; L32-I71 HydrophobicContact CD2-CD1 3.65Å; L32-I71 HydrophobicContact CD2-CG2 4.1Å; L32-I71 HydrophobicContact CG-CG2 4.49Å; L32-V78 HydrophobicContact CD1-CG1 3.7Å; L32-V78 HydrophobicContact CG-CG1 3.83Å; L32-L79 PolarHBondContact N-O 2.99Å; L32-L80 HydrophobicContact CB-CB 4.37Å; L32-L80 HydrophobicContact CB-CD1 3.6Å; L32-L80 CarbonylContact O-C 3.49Å; L32-L80 WeakPolarHBondContact O-CA 3.43Å; L32-L81 PolarHBondContact O-N 3.18Å; L32-L287 HydrophobicContact CB-CD1 4.12Å; L32-L287 HydrophobicContact CD1-CD2 4.48Å; L32-L287 HydrophobicContact CD2-CD2 4.24Å; L32-L287 HydrophobicContact CD2-CG 4.46Å; L32-G288 VanDerWaalsContact CA-O 3.28Å; L32-G288 WeakPolarHBondContact CA-O 3.31Å; L32-Y289 HydrophobicContact CD2-CD2 3.66Å
33H98.9Very high91.2Very high0 Ų023.4 Ų23.40%016%0.162CC..EExtended strand (participates in β ladder)trans-145.9150.6178.966.694.7000115.1L81 V240 Y263 V278 G288H33-L81 CarbonylContact C-O 3.56Å; H33-L81 WeakPolarHBondContact CA-O 3.44Å; H33-L81 HydrophobicContact CB-CB 4.49Å; H33-V240 HydrophobicContact CB-CG1 3.6Å; H33-Y263 AromaticContact NE2-CE2 3.79Å; H33-Y263 AromaticContact NE2-CZ 3.71Å; H33-Y263 PolarHBondContact NE2-OH 3.49Å; H33-V278 WeakPolarHBondContact NE2-CG2 3.39Å; H33-G288 PolarHBondContact N-O 3.44Å; H33-G288 WeakPolarHBondContact NE2-CA 3.46Å; H33-G288 WeakPolarHBondContact O-CA 3.48Å; H33-G288 PolarHBondContact O-N 3.15Å
34T98.9Very high93.5Very high2 Ų219.1 Ų19.11%0.01213%0.125CC..EExtended strand (participates in β ladder)trans-128.4156.8169.852.40000109.9L64 L81 D82 A83 Y110 L287T34-L64 HydrophobicContact CG2-CD1 4.44Å; T34-L64 HydrophobicContact CG2-CD2 4.18Å; T34-L81 PolarHBondContact N-O 2.92Å; T34-D82 CarbonylContact O-C 3.42Å; T34-D82 WeakPolarHBondContact O-CA 3.37Å; T34-D82 PolarHBondContact OG1-OD2 3.21Å; T34-A83 PolarHBondContact O-N 3.38Å; T34-Y110 WeakPolarHBondContact OG1-CE1 3.48Å; T34-Y110 PolarHBondContact OG1-OH 3.09Å; T34-L287 HydrophobicContact CG2-CD1 4.26Å
35N98.6Very high95.2Very high2 Ų217.1 Ų17.11%0.01111%0.108CC..  trans-152.9151.8173.365.8-83.2000108.4V37 A83 G241 A280 Y281N35-V37 PolarHBondContact O-N 2.87Å; N35-V37 VanDerWaalsContact O-N 3.13Å; N35-A83 HydrophobicContact CB-CB 3.88Å; N35-G241 WeakPolarHBondContact CB-O 3.31Å; N35-A280 WeakPolarHBondContact OD1-CA 3.25Å; N35-A280 WeakPolarHBondContact OD1-CB 3.47Å; N35-A280 PolarHBondContact OD1-N 3.33Å; N35-Y281 PolarHBondContact ND2-O 2.92Å
36D95.4Very high96.3Very high1 Ų117.3 Ų17.31%0.0059%0.093CC..  trans5439.5170.6-56.6-94.2000112.9H38 G84 D85 H220 G242 H243 N245 A282 F283D36-H38 PolarHBondContact O-CD2 2.86Å; D36-H38 PolarHBondContact O-N 3.29Å; D36-H38 IonicContact OD1-NE2 2.63Å; D36-G84 PolarHBondContact N-O 2.48Å; D36-D85 CarbonylContact C-O 3.58Å; D36-H220 IonicContact OD1-CE1 3.76Å; D36-H220 PolarHBondContact OD1-CE1 2.82Å; D36-H220 VanDerWaalsContact OD1-CE1 3.28Å; D36-H220 IonicContact OD1-NE2 2.7Å; D36-H220 IonicContact OD2-CE1 3.83Å; D36-G242 WeakPolarHBondContact OD2-CA 3.13Å; D36-H243 VanDerWaalsContact OD1-CA 3.3Å; D36-H243 WeakPolarHBondContact OD1-CA 3.47Å; D36-H243 PolarHBondContact OD1-N 3.48Å; D36-H243 PolarHBondContact OD2-N 3.33Å; D36-N245 WeakPolarHBondContact CB-OD1 3.32Å; D36-N245 PolarHBondContact OD1-OD1 2.91Å; D36-A282 HydrophobicContact CB-CB 3.85Å; D36-F283 PolarHBondContact O-N 3.19Å
37V97.9Very high96Very high13 Ų1316.3 Ų16.38%0.0798%0.079CC..  trans-64.4-29.7-178.2175.50000111.1N35 S39 R40 D85 F283N35-V37 PolarHBondContact O-N 2.87Å; N35-V37 VanDerWaalsContact O-N 3.13Å; V37-S39 PolarHBondContact O-N 2.84Å; V37-R40 WeakPolarHBondContact O-CB 3.28Å; V37-R40 WeakPolarHBondContact O-CG 3.32Å; V37-R40 PolarHBondContact O-N 2.97Å; V37-D85 PolarHBondContact N-O 3.14Å; V37-D85 VanDerWaalsContact N-O 3.16Å; V37-F283 WeakPolarHBondContact O-CA 3.44Å
38H93.1Very high95.5Very high6 Ų614.6 Ų14.63%0.0287%0.073CC..THydrogen-bonded Turntrans46.456172.9-69.2-49.5000113.5D36 R40 D85 Y87 Q88 H118 F283D36-H38 PolarHBondContact O-CD2 2.86Å; D36-H38 PolarHBondContact O-N 3.29Å; D36-H38 IonicContact OD1-NE2 2.63Å; H38-R40 PolarHBondContact O-N 2.98Å; H38-R40 PolarHBondContact O-NH1 2.89Å; H38-D85 IonicContact CE1-OD2 3.97Å; H38-D85 PolarHBondContact CE1-OD2 2.71Å; H38-D85 PolarHBondContact N-O 2.93Å; H38-Y87 PolarHBondContact ND1-O 2.95Å; H38-Q88 CarbonylContact C-O 3.58Å; H38-Q88 WeakPolarHBondContact CA-O 3.33Å; H38-Q88 WeakPolarHBondContact CB-O 3.38Å; H38-H118 AromaticContact CE1-CD2 3.64Å; H38-F283 HydrophobicContact CB-CD1 4.13Å; H38-F283 HydrophobicContact CB-CE1 4.23Å; H38-F283 AromaticContact CD2-CE1 3.7Å
39S95.9Very high94.9Very high0 Ų012.5 Ų12.50%06%0.064CC..THydrogen-bonded Turntrans56.226.6172.8-51.60000114.9V37 L41 Q86 Q88 T90 F93V37-S39 PolarHBondContact O-N 2.84Å; S39-L41 PolarHBondContact O-N 2.82Å; S39-Q86 PolarHBondContact N-O 3.43Å; S39-Q86 PolarHBondContact OG-O 3.08Å; S39-Q88 WeakPolarHBondContact CB-O 3.39Å; S39-Q88 PolarHBondContact N-O 3.41Å; S39-Q88 PolarHBondContact OG-N 2.87Å; S39-Q88 PolarHBondContact OG-O 2.83Å; S39-T90 WeakPolarHBondContact CB-OG1 3.38Å; S39-T90 VanDerWaalsContact O-CG2 3.31Å; S39-T90 WeakPolarHBondContact O-CG2 3.49Å; S39-T90 PolarHBondContact O-OG1 2.93Å; S39-F93 WeakPolarHBondContact OG-CB 3.18Å
40R95.8Very high94.4Very high14 Ų1416.1 Ų16.15%0.0538%0.08CC..  trans-82.162.6171.4-61.2-51.7-167.5-96.910.4111.1V37 H38 T44 S48 G89 F283V37-R40 WeakPolarHBondContact O-CB 3.28Å; V37-R40 WeakPolarHBondContact O-CG 3.32Å; V37-R40 PolarHBondContact O-N 2.97Å; H38-R40 PolarHBondContact O-N 2.98Å; H38-R40 PolarHBondContact O-NH1 2.89Å; R40-T44 HydrophobicContact CB-CG2 4.07Å; R40-T44 HydrophobicContact CG-CG2 4.01Å; R40-S48 PolarHBondContact NE-O 3.08Å; R40-S48 PolarHBondContact NH2-O 2.8Å; R40-G89 VanDerWaalsContact NH1-C 3.34Å; R40-G89 PolarHBondContact NH1-O 3.15Å; R40-F283 WeakPolarHBondContact CB-O 3.47Å; R40-F283 HydrophobicContact CG-CB 3.97Å; R40-F283 HydrophobicContact CG-CD1 4.37Å
41L96.9Very high94Very high8 Ų817.4 Ų17.44%0.0429%0.089CC..  trans-66.1-45.6178.6-78.9-62.3000110.8S39 G60 V61 W92 E100 F104S39-L41 PolarHBondContact O-N 2.82Å; L41-G60 CarbonylContact O-C 3.53Å; L41-G60 WeakPolarHBondContact O-CA 3.49Å; L41-V61 HydrophobicContact CD1-CB 4.32Å; L41-V61 HydrophobicContact CD1-CG1 4.02Å; L41-V61 WeakPolarHBondContact O-CG1 3.29Å; L41-V61 PolarHBondContact O-N 2.87Å; L41-W92 HydrophobicContact CB-CD2 4.04Å; L41-W92 HydrophobicContact CB-CE3 4.35Å; L41-W92 HydrophobicContact CB-CG 4.34Å; L41-W92 HydrophobicContact CD2-CB 4.36Å; L41-W92 HydrophobicContact CD2-CG 4.5Å; L41-W92 HydrophobicContact CG-CD2 4.3Å; L41-W92 HydrophobicContact CG-CE3 4.28Å; L41-E100 HydrophobicContact CD2-CG 3.94Å; L41-E100 HydrophobicContact CG-CG 4.17Å; L41-F104 HydrophobicContact CD1-CB 3.95Å; L41-F104 HydrophobicContact CD1-CD2 3.41Å; L41-F104 VanDerWaalsContact CD1-CD2 3.41Å; L41-F104 HydrophobicContact CD1-CE2 4.19Å; L41-F104 HydrophobicContact CD1-CG 3.88Å; L41-F104 HydrophobicContact CG-CD2 4.22Å
42E97.2Very high93.3Very high52 Ų5221.4 Ų21.424%0.24311%0.113CC..SBendtrans-76.8157.7172-67.2177-94.900111.4W92 I324 R328E42-W92 HydrophobicContact CG-CZ2 3.75Å; E42-W92 PolarHBondContact OE1-NE1 3.42Å; E42-I324 HydrophobicContact CG-CG2 3.74Å; E42-R328 VanDerWaalsContact OE1-CD 3.28Å; E42-R328 WeakPolarHBondContact OE1-CD 3Å; E42-R328 IonicContact OE1-CZ 3.34Å; E42-R328 IonicContact OE1-NE 3.23Å; E42-R328 PolarHBondContact OE1-NE 3.29Å; E42-R328 IonicContact OE2-NE 2.76Å; E42-R328 PolarHBondContact OE2-NE 2.93Å
43Q96.9Very high92.8Very high26 Ų2625.3 Ų25.312%0.12113%0.134CC..  trans-62149.4168.564.417412.100111.2C51 C57 M58Q43-C51 HydrophobicContact CG-CB 4.25Å; Q43-C51 PolarHBondContact NE2-SG 3.26Å; Q43-C51 VanDerWaalsContact NE2-SG 3.43Å; Q43-C51 WeakPolarHBondContact O-CB 3.46Å; Q43-C57 HydrophobicContact CB-CB 4.16Å; Q43-C57 VanDerWaalsContact CD-CB 3.47Å; Q43-C57 HydrophobicContact CG-CB 3.86Å; Q43-M58 CarbonylContact C-O 3.51Å; Q43-M58 WeakPolarHBondContact CA-O 3.33Å
44T93.4Very high92.3Very high6 Ų628.1 Ų28.14%0.03716%0.157CC..BIsolated β-bridgetrans-119167.9-174.356.90000111.2R40 S49 C57 M58R40-T44 HydrophobicContact CB-CG2 4.07Å; R40-T44 HydrophobicContact CG-CG2 4.01Å; T44-S49 WeakPolarHBondContact CA-O 3.36Å; T44-S49 VanDerWaalsContact CB-O 3.27Å; T44-S49 WeakPolarHBondContact CB-O 3.49Å; T44-C57 CarbonylContact O-C 3.44Å; T44-C57 WeakPolarHBondContact O-CA 3.33Å; T44-C57 WeakPolarHBondContact O-CB 3.34Å; T44-M58 PolarHBondContact N-O 2.81Å; T44-M58 PolarHBondContact O-N 2.65Å; T44-M58 PolarHBondContact OG1-O 2.96Å
45S90.8Very high92Very high18 Ų1831.5 Ų31.513%0.12618%0.181CC..  trans-64.6174.9163.6550000111.2D47 S48 S49S45-D47 WeakPolarHBondContact CB-OD1 3.35Å; S45-D47 PolarHBondContact O-N 2.94Å; S45-D47 PolarHBondContact OG-OD1 2.97Å; S45-S48 PolarHBondContact O-N 3.3Å; S45-S49 PolarHBondContact N-O 3.24Å; S45-S49 VanDerWaalsContact OG-C 3.3Å; S45-S49 WeakPolarHBondContact OG-CA 3.16Å; S45-S49 PolarHBondContact OG-N 2.93Å; S45-S49 PolarHBondContact OG-O 3.31Å; S45-S49 VanDerWaalsContact OG-O 3.11Å; S45-S49 PolarHBondContact OG-OG 3.05Å
46E91.5Very high91.7Very high63 Ų6339.6 Ų39.629%0.29421%0.211SC..THydrogen-bonded Turntrans-59.9-29.5178.8-177.2176-134.500113.6S48 M58 S255 K256 K285E46-S48 VanDerWaalsContact C-N 3.34Å; E46-M58 HydrophobicContact CB-CE 3.99Å; E46-M58 HydrophobicContact CB-SD 4.36Å; E46-M58 HydrophobicContact CG-CE 3.79Å; E46-M58 HydrophobicContact CG-SD 4.22Å; E46-S255 PolarHBondContact OE1-OG 2.75Å; E46-S255 VanDerWaalsContact OE1-OG 3.06Å; E46-K256 HydrophobicContact CG-CD 4.28Å; E46-K256 WeakPolarHBondContact OE2-CD 3.33Å; E46-K256 WeakPolarHBondContact OE2-CE 3.12Å; E46-K256 IonicContact OE2-NZ 2.91Å; E46-K256 PolarHBondContact OE2-NZ 2.63Å; E46-K285 PolarHBondContact O-NZ 2.94Å
47D83.7Confident91.6Very high39 Ų3939.6 Ų39.621%0.20921%0.211CC..THydrogen-bonded Turntrans-94.515.4177.667.2-5.2000113.4S45 S49 Y345 P397S45-D47 WeakPolarHBondContact CB-OD1 3.35Å; S45-D47 PolarHBondContact O-N 2.94Å; S45-D47 PolarHBondContact OG-OD1 2.97Å; D47-S49 PolarHBondContact O-N 2.84Å; D47-S49 WeakPolarHBondContact OD1-CB 3.43Å; D47-S49 PolarHBondContact OD1-N 2.94Å; D47-S49 PolarHBondContact OD1-OG 3.2Å; D47-Y345 WeakPolarHBondContact OD2-CE2 3.27Å; D47-Y345 PolarHBondContact OD2-OH 3.04Å; D47-P397 HydrophobicContact CB-CG 4.08Å; D47-P397 VanDerWaalsContact OD2-CG 3.25Å; D47-P397 WeakPolarHBondContact OD2-CG 3.33Å
48S87.8Confident91.6Very high2 Ų239.8 Ų39.81%0.01421%0.211CC..SBendtrans65.713.9177.5-55.50000115.6R40 S45 E46 F283R40-S48 PolarHBondContact NE-O 3.08Å; R40-S48 PolarHBondContact NH2-O 2.8Å; S45-S48 PolarHBondContact O-N 3.3Å; E46-S48 VanDerWaalsContact C-N 3.34Å; S48-F283 WeakPolarHBondContact OG-CB 3.36Å; S48-F283 WeakPolarHBondContact OG-CD2 3.48Å
49S84.6Confident91.8Very high8 Ų839.5 Ų39.56%0.05621%0.21CC..SBendtrans-82.4-172.9166.973.20000111.7T44 S45 D47 C51 P397T44-S49 WeakPolarHBondContact CA-O 3.36Å; T44-S49 VanDerWaalsContact CB-O 3.27Å; T44-S49 WeakPolarHBondContact CB-O 3.49Å; S45-S49 PolarHBondContact N-O 3.24Å; S45-S49 VanDerWaalsContact OG-C 3.3Å; S45-S49 WeakPolarHBondContact OG-CA 3.16Å; S45-S49 PolarHBondContact OG-N 2.93Å; S45-S49 PolarHBondContact OG-O 3.31Å; S45-S49 VanDerWaalsContact OG-O 3.11Å; S45-S49 PolarHBondContact OG-OG 3.05Å; D47-S49 PolarHBondContact O-N 2.84Å; D47-S49 WeakPolarHBondContact OD1-CB 3.43Å; D47-S49 PolarHBondContact OD1-N 2.94Å; D47-S49 PolarHBondContact OD1-OG 3.2Å; S49-C51 PolarHBondContact O-N 2.88Å; S49-P397 WeakPolarHBondContact CB-O 3.35Å
50K88.3Confident91.9Very high77 Ų7739.7 Ų39.734%0.33521%0.212SC..BIsolated β-bridgetrans-60.5126.9-177.2-177.4171.8179.3170.10110.6V52 E409K50-V52 PolarHBondContact O-N 3.39Å; K50-E409 WeakPolarHBondContact CE-OE2 3.47Å; K50-E409 IonicContact NZ-OE1 3.74Å; K50-E409 IonicContact NZ-OE2 3.81Å; K50-E409 PolarHBondContact NZ-OE2 3.46Å
51C89.8Confident92Very high29 Ų2939.7 Ų39.720%0.19621%0.213CC..  trans-63.6125.8173.51710000111Q43 S49 C57Q43-C51 HydrophobicContact CG-CB 4.25Å; Q43-C51 PolarHBondContact NE2-SG 3.26Å; Q43-C51 VanDerWaalsContact NE2-SG 3.43Å; Q43-C51 WeakPolarHBondContact O-CB 3.46Å; S49-C51 PolarHBondContact O-N 2.88Å; C51-C57 VanDerWaalsContact CA-SG 3.6Å; C51-C57 HydrophobicContact CB-CB 3.93Å; C51-C57 WeakPolarHBondContact CB-SG 3.46Å; C51-C57 WeakPolarHBondContact SG-CB 3.17Å; C51-C57 CovalentContact SG-SG 2.01Å; C51-C57 PolarHBondContact SG-SG 3.47Å
52V85.1Confident92.1Very high84 Ų8439.3 Ų39.351%0.50921%0.211SC..  trans-113.9-51174.4177.70000110.3K50 N402K50-V52 PolarHBondContact O-N 3.39Å; V52-N402 HydrophobicContact CB-CB 4.35Å; V52-N402 HydrophobicContact CG1-CB 3.7Å; V52-N402 HydrophobicContact CG2-CB 3.77Å
53N88.3Confident92.2Very high82 Ų8237.2 Ų37.244%0.43920%0.201SC..  trans-98.695.1177.8-176.6-9.7000110.6S55 R56 C57N53-S55 PolarHBondContact O-N 3.03Å; N53-S55 PolarHBondContact OD1-N 3.08Å; N53-S55 PolarHBondContact OD1-OG 2.87Å; N53-R56 PolarHBondContact O-N 2.81Å; N53-C57 VanDerWaalsContact C-SG 3.54Å; N53-C57 PolarHBondContact O-N 2.84Å; N53-C57 PolarHBondContact O-SG 2.98Å
54A89.3Confident92.3Very high59 Ų5936.4 Ų36.449%0.48820%0.198SC..G310 helixtrans-51.4-29.8-176.800000114.6R56 C57A54-R56 PolarHBondContact O-N 3.18Å; A54-C57 PolarHBondContact O-N 3.47Å
55S91.3Very high92.5Very high73 Ų7337.7 Ų37.751%0.5120%0.203SC..G310 helixtrans-66.8-19.4178.669.10000114.1N53 S312N53-S55 PolarHBondContact O-N 3.03Å; N53-S55 PolarHBondContact OD1-N 3.08Å; N53-S55 PolarHBondContact OD1-OG 2.87Å; S55-S312 VanDerWaalsContact O-CB 3.24Å; S55-S312 WeakPolarHBondContact O-CB 3.33Å; S55-S312 PolarHBondContact O-OG 2.77Å
56R92.1Very high92.9Very high171 Ų17137.7 Ų37.765%0.64520%0.202SC*.G310 helixtrans-114.32.7179.8-61.4-173.7-177.71780.4113.1N53 A54N53-R56 PolarHBondContact O-N 2.81Å; A54-R56 PolarHBondContact O-N 3.18Å
57C94.4Very high93.3Very high1 Ų136.5 Ų36.51%0.00720%0.196CC..  trans-76.3151.5-177.7-65.30000111.7Q43 T44 C51 N53 A54Q43-C57 HydrophobicContact CB-CB 4.16Å; Q43-C57 VanDerWaalsContact CD-CB 3.47Å; Q43-C57 HydrophobicContact CG-CB 3.86Å; T44-C57 CarbonylContact O-C 3.44Å; T44-C57 WeakPolarHBondContact O-CA 3.33Å; T44-C57 WeakPolarHBondContact O-CB 3.34Å; C51-C57 VanDerWaalsContact CA-SG 3.6Å; C51-C57 HydrophobicContact CB-CB 3.93Å; C51-C57 WeakPolarHBondContact CB-SG 3.46Å; C51-C57 WeakPolarHBondContact SG-CB 3.17Å; C51-C57 CovalentContact SG-SG 2.01Å; C51-C57 PolarHBondContact SG-SG 3.47Å; N53-C57 VanDerWaalsContact C-SG 3.54Å; N53-C57 PolarHBondContact O-N 2.84Å; N53-C57 PolarHBondContact O-SG 2.98Å; A54-C57 PolarHBondContact O-N 3.47Å
58M96.9Very high94Very high18 Ų1834.7 Ų34.79%0.08919%0.186CC..BIsolated β-bridgetrans-132.2162.9-170.4-54.6-175.8-177.700110.6Q43 T44 E46 K285 L309 L310 N311Q43-M58 CarbonylContact C-O 3.51Å; Q43-M58 WeakPolarHBondContact CA-O 3.33Å; T44-M58 PolarHBondContact N-O 2.81Å; T44-M58 PolarHBondContact O-N 2.65Å; T44-M58 PolarHBondContact OG1-O 2.96Å; E46-M58 HydrophobicContact CB-CE 3.99Å; E46-M58 HydrophobicContact CB-SD 4.36Å; E46-M58 HydrophobicContact CG-CE 3.79Å; E46-M58 HydrophobicContact CG-SD 4.22Å; M58-K285 HydrophobicContact CB-CG 4.44Å; M58-K285 HydrophobicContact SD-CD 4.38Å; M58-K285 VanDerWaalsContact SD-CE 3.56Å; M58-K285 HydrophobicContact SD-CG 4.39Å; M58-L309 HydrophobicContact SD-CD1 3.88Å; M58-L310 CarbonylContact C-O 3.57Å; M58-L310 WeakPolarHBondContact CA-O 3.31Å; M58-N311 HydrophobicContact CG-CB 4.42Å
59G98Very high94.5Very high0 Ų036.1 Ų36.10%019%0.193CC..  trans63.1-147.1176.900000113.3R63 G284 L310G59-R63 WeakPolarHBondContact O-CB 3.35Å; G59-R63 PolarHBondContact O-NH1 3.38Å; G59-G284 WeakPolarHBondContact CA-O 3.35Å; G59-L310 PolarHBondContact N-O 3.26Å
60G97.9Very high95.2Very high4 Ų439.6 Ų39.64%0.04121%0.208CC..  trans79.9144-174.600000112.6L41 A62 R63 L64L41-G60 CarbonylContact O-C 3.53Å; L41-G60 WeakPolarHBondContact O-CA 3.49Å; G60-A62 VanDerWaalsContact C-N 3.27Å; G60-A62 PolarHBondContact O-N 2.76Å; G60-R63 PolarHBondContact O-N 3.11Å; G60-R63 VanDerWaalsContact O-N 3.16Å; G60-L64 PolarHBondContact O-N 3.04Å
61V98.3Very high95.7Very high13 Ų1336.7 Ų36.78%0.07920%0.196CC..Hα-helixtrans-66.3-28.6-170.271.40000113L41 F65 F104 L108 I320 I324L41-V61 HydrophobicContact CD1-CB 4.32Å; L41-V61 HydrophobicContact CD1-CG1 4.02Å; L41-V61 WeakPolarHBondContact O-CG1 3.29Å; L41-V61 PolarHBondContact O-N 2.87Å; V61-F65 WeakPolarHBondContact O-CB 3.39Å; V61-F65 PolarHBondContact O-N 2.83Å; V61-F104 HydrophobicContact CG1-CB 4.3Å; V61-F104 HydrophobicContact CG1-CD1 3.88Å; V61-F104 HydrophobicContact CG1-CE1 4.38Å; V61-F104 HydrophobicContact CG1-CG 4.01Å; V61-F104 HydrophobicContact CG2-CB 3.94Å; V61-L108 HydrophobicContact CG2-CD1 3.28Å; V61-L108 HydrophobicContact CG2-CD2 3.82Å; V61-L108 HydrophobicContact CG2-CG 4.22Å; V61-I320 HydrophobicContact CG1-CG2 3.98Å; V61-I324 HydrophobicContact CG1-CD1 3.52Å; V61-I324 HydrophobicContact CG1-CG1 4Å
62A98.8Very high96.1Very high0 Ų037.8 Ų37.80%020%0.196CC..Hα-helixtrans-66.7-39.2175.300000113.1G60 T66 E316 D317 I320 K321 I324G60-A62 VanDerWaalsContact C-N 3.27Å; G60-A62 PolarHBondContact O-N 2.76Å; A62-T66 PolarHBondContact O-N 2.88Å; A62-T66 PolarHBondContact O-OG1 2.97Å; A62-E316 HydrophobicContact CB-CB 3.83Å; A62-E316 HydrophobicContact CB-CG 4.21Å; A62-D317 WeakPolarHBondContact O-CB 3.46Å; A62-D317 PolarHBondContact O-N 2.85Å; A62-I320 HydrophobicContact CB-CB 4.05Å; A62-I320 HydrophobicContact CB-CG2 3.86Å; A62-K321 HydrophobicContact CB-CB 4.18Å; A62-I324 HydrophobicContact CB-CD1 3.9Å
63R98.8Very high96.8Very high8 Ų843.9 Ų43.93%0.0321%0.21CC..Hα-helixtrans-75.3-39.6176.9-176.6173.9-73.6106.1-1.2111.6G59 G60 F65 T66 K67 L310 N311 I314 E316G59-R63 WeakPolarHBondContact O-CB 3.35Å; G59-R63 PolarHBondContact O-NH1 3.38Å; G60-R63 PolarHBondContact O-N 3.11Å; G60-R63 VanDerWaalsContact O-N 3.16Å; R63-F65 VanDerWaalsContact C-N 3.3Å; R63-F65 PolarHBondContact O-N 2.74Å; R63-T66 PolarHBondContact O-N 2.91Å; R63-K67 PolarHBondContact O-N 3.1Å; R63-K67 VanDerWaalsContact O-N 3.14Å; R63-L310 VanDerWaalsContact CD-C 3.48Å; R63-L310 WeakPolarHBondContact CD-O 3.44Å; R63-L310 HydrophobicContact CG-CB 4.23Å; R63-N311 VanDerWaalsContact CD-O 3.24Å; R63-N311 WeakPolarHBondContact CD-O 3.45Å; R63-N311 PolarHBondContact NE-O 3.17Å; R63-N311 VanDerWaalsContact NE-O 3.12Å; R63-I314 HydrophobicContact CG-CB 3.84Å; R63-I314 HydrophobicContact CG-CG2 3.71Å; R63-I314 PolarHBondContact NE-O 3.16Å; R63-E316 HydrophobicContact CB-CG 4.25Å
64L98.9Very high97.2Very high10 Ų1043.6 Ų43.65%0.05222%0.219CC..Hα-helixtrans-55.7-48172.2175.260.9000110.5T34 G60 T66 K67 V68 L108 L287 L310T34-L64 HydrophobicContact CG2-CD1 4.44Å; T34-L64 HydrophobicContact CG2-CD2 4.18Å; G60-L64 PolarHBondContact O-N 3.04Å; L64-T66 VanDerWaalsContact C-N 3.34Å; L64-T66 PolarHBondContact O-N 2.83Å; L64-K67 PolarHBondContact O-N 2.71Å; L64-K67 VanDerWaalsContact O-N 3.14Å; L64-V68 HydrophobicContact CD1-CG2 3.82Å; L64-V68 HydrophobicContact CG-CG2 4.2Å; L64-V68 WeakPolarHBondContact O-CB 3.24Å; L64-V68 WeakPolarHBondContact O-CG2 3.44Å; L64-V68 PolarHBondContact O-N 2.68Å; L64-L108 HydrophobicContact CB-CD2 4.25Å; L64-L108 HydrophobicContact CD2-CD2 3.4Å; L64-L108 HydrophobicContact CG-CD2 3.55Å; L64-L287 HydrophobicContact CD1-CB 4.02Å; L64-L287 HydrophobicContact CD1-CD1 3.7Å; L64-L287 HydrophobicContact CD1-CD2 4.03Å; L64-L287 HydrophobicContact CD1-CG 4.12Å; L64-L310 HydrophobicContact CB-CD1 3.97Å; L64-L310 HydrophobicContact CD1-CD1 3.96Å
65F98.9Very high97.7Very high32 Ų3242.5 Ų42.514%0.1420%0.204CC..Hα-helixtrans-53.8-49.3176.8-176.6-87.5000112V61 R63 K67 V68 Q69 A107 L108 D317 I320V61-F65 WeakPolarHBondContact O-CB 3.39Å; V61-F65 PolarHBondContact O-N 2.83Å; R63-F65 VanDerWaalsContact C-N 3.3Å; R63-F65 PolarHBondContact O-N 2.74Å; F65-K67 VanDerWaalsContact C-N 3.34Å; F65-K67 PolarHBondContact O-N 2.81Å; F65-V68 PolarHBondContact O-N 3.04Å; F65-Q69 HydrophobicContact CD1-CG 3.86Å; F65-Q69 HydrophobicContact CD2-CG 4.44Å; F65-Q69 HydrophobicContact CE1-CG 3.63Å; F65-Q69 HydrophobicContact CE2-CG 4.21Å; F65-Q69 HydrophobicContact CG-CG 4.28Å; F65-Q69 HydrophobicContact CZ-CG 3.81Å; F65-Q69 WeakPolarHBondContact O-CB 3.35Å; F65-Q69 WeakPolarHBondContact O-CG 3.43Å; F65-Q69 PolarHBondContact O-N 2.96Å; F65-A107 WeakPolarHBondContact CE2-O 3.47Å; F65-L108 HydrophobicContact CB-CD1 4.11Å; F65-L108 HydrophobicContact CB-CG 4.27Å; F65-L108 HydrophobicContact CD2-CD1 3.88Å; F65-L108 HydrophobicContact CD2-CG 4.01Å; F65-D317 HydrophobicContact CB-CB 4.35Å; F65-D317 HydrophobicContact CD1-CB 3.58Å; F65-D317 VanDerWaalsContact CD1-CG 3.48Å; F65-D317 WeakPolarHBondContact CD1-OD2 3.47Å; F65-D317 HydrophobicContact CE1-CB 4.27Å; F65-D317 WeakPolarHBondContact CE1-OD2 3.22Å; F65-D317 HydrophobicContact CG-CB 4.3Å; F65-I320 HydrophobicContact CB-CG1 4.01Å; F65-I320 HydrophobicContact CD1-CG1 4.03Å; F65-I320 HydrophobicContact CD2-CD1 3.98Å; F65-I320 HydrophobicContact CD2-CG1 3.8Å; F65-I320 HydrophobicContact CE1-CG1 4.42Å; F65-I320 HydrophobicContact CE2-CD1 4.13Å; F65-I320 HydrophobicContact CE2-CG1 4.24Å; F65-I320 HydrophobicContact CG-CD1 4.38Å; F65-I320 HydrophobicContact CG-CG1 3.69Å
66T98.9Very high97.9Very high18 Ų1844 Ų4411%0.1121%0.212CC..Hα-helixtrans-56.1-47.7177.7-61.90000111.9A62 R63 L64 Q69 Q70 I314 P315 D317A62-T66 PolarHBondContact O-N 2.88Å; A62-T66 PolarHBondContact O-OG1 2.97Å; R63-T66 PolarHBondContact O-N 2.91Å; L64-T66 VanDerWaalsContact C-N 3.34Å; L64-T66 PolarHBondContact O-N 2.83Å; T66-Q69 PolarHBondContact O-N 3.02Å; T66-Q70 VanDerWaalsContact O-CG 3.3Å; T66-Q70 WeakPolarHBondContact O-CG 3.48Å; T66-Q70 PolarHBondContact O-N 2.91Å; T66-I314 HydrophobicContact CG2-CG2 3.94Å; T66-P315 WeakPolarHBondContact CB-O 3.26Å; T66-P315 HydrophobicContact CG2-CG 4.19Å; T66-P315 PolarHBondContact OG1-O 3.2Å; T66-P315 VanDerWaalsContact OG1-O 3.06Å; T66-D317 PolarHBondContact OG1-N 3.23Å; T66-D317 VanDerWaalsContact OG1-N 3.15Å
67K98.9Very high98.2Very high39 Ų3936.9 Ų36.917%0.1719%0.187CC..Hα-helixtrans-68-43.8-178.7-176.65562.1-174.80112.2R63 L64 F65 Q69 Q70 I71 L287 I308 L310 I314R63-K67 PolarHBondContact O-N 3.1Å; R63-K67 VanDerWaalsContact O-N 3.14Å; L64-K67 PolarHBondContact O-N 2.71Å; L64-K67 VanDerWaalsContact O-N 3.14Å; F65-K67 VanDerWaalsContact C-N 3.34Å; F65-K67 PolarHBondContact O-N 2.81Å; K67-Q69 VanDerWaalsContact C-N 3.3Å; K67-Q69 PolarHBondContact O-N 2.89Å; K67-Q70 WeakPolarHBondContact O-CB 3.45Å; K67-Q70 PolarHBondContact O-N 3.37Å; K67-I71 HydrophobicContact CD-CD1 4.01Å; K67-I71 HydrophobicContact CD-CG1 4.29Å; K67-I71 HydrophobicContact CG-CD1 4.03Å; K67-I71 WeakPolarHBondContact O-CG1 3.39Å; K67-I71 PolarHBondContact O-N 3.3Å; K67-I71 VanDerWaalsContact O-N 3.1Å; K67-L287 HydrophobicContact CB-CD2 4.29Å; K67-L287 HydrophobicContact CG-CD2 3.77Å; K67-I308 HydrophobicContact CD-CD1 4.19Å; K67-I308 HydrophobicContact CD-CG2 4.33Å; K67-I308 HydrophobicContact CG-CD1 4.29Å; K67-I308 HydrophobicContact CG-CG2 4.33Å; K67-L310 HydrophobicContact CB-CD2 3.93Å; K67-L310 HydrophobicContact CG-CD2 4.17Å; K67-I314 HydrophobicContact CB-CG2 4.4Å
68V98.9Very high98.4Very high0 Ų037.9 Ų37.90%019%0.193CC..Hα-helixtrans-56.4-46.3175.6166.70000110.7L32 L64 F65 Q70 I71 R72 L80 L287L32-V68 HydrophobicContact CD1-CB 4.46Å; L32-V68 HydrophobicContact CD1-CG1 4.28Å; L32-V68 HydrophobicContact CD1-CG2 4.25Å; L64-V68 HydrophobicContact CD1-CG2 3.82Å; L64-V68 HydrophobicContact CG-CG2 4.2Å; L64-V68 WeakPolarHBondContact O-CB 3.24Å; L64-V68 WeakPolarHBondContact O-CG2 3.44Å; L64-V68 PolarHBondContact O-N 2.68Å; F65-V68 PolarHBondContact O-N 3.04Å; V68-Q70 PolarHBondContact O-N 3.46Å; V68-I71 PolarHBondContact O-N 3.11Å; V68-R72 HydrophobicContact CG1-CG 4.43Å; V68-R72 WeakPolarHBondContact O-CG 3.41Å; V68-R72 PolarHBondContact O-N 3.49Å; V68-L80 HydrophobicContact CG1-CD2 4.01Å; V68-L80 HydrophobicContact CG2-CD1 4.14Å; V68-L80 HydrophobicContact CG2-CD2 4.14Å; V68-L287 HydrophobicContact CG2-CD1 4.5Å; V68-L287 HydrophobicContact CG2-CD2 3.91Å
69Q98.8Very high98.5Very high32 Ų3237.2 Ų37.215%0.1519%0.189CC..Hα-helixtrans-69.8-32.2-178.4-66.4-72.1104.200112.7F65 T66 K67 R73F65-Q69 HydrophobicContact CD1-CG 3.86Å; F65-Q69 HydrophobicContact CD2-CG 4.44Å; F65-Q69 HydrophobicContact CE1-CG 3.63Å; F65-Q69 HydrophobicContact CE2-CG 4.21Å; F65-Q69 HydrophobicContact CG-CG 4.28Å; F65-Q69 HydrophobicContact CZ-CG 3.81Å; F65-Q69 WeakPolarHBondContact O-CB 3.35Å; F65-Q69 WeakPolarHBondContact O-CG 3.43Å; F65-Q69 PolarHBondContact O-N 2.96Å; T66-Q69 PolarHBondContact O-N 3.02Å; K67-Q69 VanDerWaalsContact C-N 3.3Å; K67-Q69 PolarHBondContact O-N 2.89Å; Q69-R73 WeakPolarHBondContact O-CD 3.41Å; Q69-R73 VanDerWaalsContact O-CG 3.26Å; Q69-R73 WeakPolarHBondContact O-CG 3.49Å; Q69-R73 PolarHBondContact O-N 3.5Å
70Q98.8Very high98.5Very high82 Ų8237.2 Ų37.238%0.38319%0.189SC..Hα-helixtrans-61.6-45.5171-74.4170.93.400111T66 K67 V68 R73 A74T66-Q70 VanDerWaalsContact O-CG 3.3Å; T66-Q70 WeakPolarHBondContact O-CG 3.48Å; T66-Q70 PolarHBondContact O-N 2.91Å; K67-Q70 WeakPolarHBondContact O-CB 3.45Å; K67-Q70 PolarHBondContact O-N 3.37Å; V68-Q70 PolarHBondContact O-N 3.46Å; Q70-R73 PolarHBondContact O-N 3.42Å; Q70-A74 PolarHBondContact O-N 2.82Å
71I98.8Very high98.6Very high15 Ų1537 Ų378%0.07719%0.187CC..Hα-helixtrans-69.7-44.8-177.8-62.9166.7000110.9T30 L32 K67 V68 R73 A74 E75 L287 Y289 I308T30-I71 HydrophobicContact CG2-CG2 4.03Å; L32-I71 HydrophobicContact CD1-CB 4.22Å; L32-I71 HydrophobicContact CD1-CD1 4.3Å; L32-I71 HydrophobicContact CD1-CG2 4.17Å; L32-I71 HydrophobicContact CD2-CD1 3.65Å; L32-I71 HydrophobicContact CD2-CG2 4.1Å; L32-I71 HydrophobicContact CG-CG2 4.49Å; K67-I71 HydrophobicContact CD-CD1 4.01Å; K67-I71 HydrophobicContact CD-CG1 4.29Å; K67-I71 HydrophobicContact CG-CD1 4.03Å; K67-I71 WeakPolarHBondContact O-CG1 3.39Å; K67-I71 PolarHBondContact O-N 3.3Å; K67-I71 VanDerWaalsContact O-N 3.1Å; V68-I71 PolarHBondContact O-N 3.11Å; I71-R73 PolarHBondContact O-N 3.4Å; I71-R73 VanDerWaalsContact O-N 3.09Å; I71-A74 PolarHBondContact O-N 3.21Å; I71-E75 HydrophobicContact CG2-CB 4.36Å; I71-E75 HydrophobicContact CG2-CG 3.79Å; I71-E75 PolarHBondContact O-N 3.39Å; I71-L287 HydrophobicContact CD1-CD2 4.11Å; I71-Y289 HydrophobicContact CD1-CD2 3.96Å; I71-Y289 HydrophobicContact CD1-CE2 4.32Å; I71-Y289 HydrophobicContact CG2-CD2 4.47Å; I71-Y289 HydrophobicContact CG2-CE2 4.04Å; I71-I308 HydrophobicContact CD1-CD1 3.78Å
72R98.7Very high98.6Very high53 Ų5336.4 Ų36.420%0.218%0.184CC..Hα-helixtrans-59-22175.7-76.9179168.1158.1-5.6114.7V68 V78 L108 R109 D111V68-R72 HydrophobicContact CG1-CG 4.43Å; V68-R72 WeakPolarHBondContact O-CG 3.41Å; V68-R72 PolarHBondContact O-N 3.49Å; R72-V78 HydrophobicContact CG-CB 4.23Å; R72-V78 HydrophobicContact CG-CG1 4.04Å; R72-V78 HydrophobicContact CG-CG2 4.48Å; R72-L108 PolarHBondContact NH1-O 3Å; R72-R109 PolarHBondContact NH2-O 2.59Å; R72-D111 IonicContact NH2-OD2 2.69Å; R72-D111 PolarHBondContact NH2-OD2 3.25Å
73R98.6Very high98.6Very high211 Ų21136.4 Ų36.480%0.79618%0.184SC*.Hα-helixtrans-86.1-24.4174.6-71.6171.3-175.3177.92.6112.7Q69 Q70 I71Q69-R73 WeakPolarHBondContact O-CD 3.41Å; Q69-R73 VanDerWaalsContact O-CG 3.26Å; Q69-R73 WeakPolarHBondContact O-CG 3.49Å; Q69-R73 PolarHBondContact O-N 3.5Å; Q70-R73 PolarHBondContact O-N 3.42Å; I71-R73 PolarHBondContact O-N 3.4Å; I71-R73 VanDerWaalsContact O-N 3.09Å
74A98.4Very high98.5Very high77 Ų7736 Ų3664%0.63618%0.182SC*.Hα-helixtrans-95.5-32.8-175.400000112.5Q70 I71Q70-A74 PolarHBondContact O-N 2.82Å; I71-A74 PolarHBondContact O-N 3.21Å
75E97.9Very high98.4Very high35 Ų3535.6 Ų35.616%0.16418%0.18CC..  trans-111.1134.4-174.6-54.9-70.8-176.800110T30 I71 V78 Y289 K291T30-E75 HydrophobicContact CG2-CG 4.49Å; I71-E75 HydrophobicContact CG2-CB 4.36Å; I71-E75 HydrophobicContact CG2-CG 3.79Å; I71-E75 PolarHBondContact O-N 3.39Å; E75-V78 HydrophobicContact CB-CG2 3.65Å; E75-V78 WeakPolarHBondContact O-CG2 3.4Å; E75-Y289 PolarHBondContact OE1-OH 3.43Å; E75-K291 IonicContact OE1-NZ 2.97Å; E75-K291 PolarHBondContact OE1-NZ 2.82Å; E75-K291 IonicContact OE2-NZ 2.84Å; E75-K291 PolarHBondContact OE2-NZ 3.16Å
76P96.2Very high98.3Very high105 Ų10534.5 Ų34.568%0.68218%0.176SC*.SBendtrans-75.6-37.1-173.728-34000113.4
77N98.6Very high98.1Very high22 Ų2233.7 Ų33.712%0.11817%0.17CC..SBendtrans-117.499.9-173.1-59.6-37.6000108.7W27 E28 L29 T30 V166W27-N77 HydrophobicContact CZ2-CB 4.03Å; W27-N77 PolarHBondContact NE1-ND2 2.77Å; W27-N77 VanDerWaalsContact NE1-ND2 3.17Å; E28-N77 VanDerWaalsContact O-CB 3.26Å; E28-N77 WeakPolarHBondContact O-CB 3.41Å; E28-N77 PolarHBondContact O-ND2 2.93Å; L29-N77 HydrophobicContact CD1-CB 4.41Å; T30-N77 PolarHBondContact N-O 3.01Å; N77-V166 HydrophobicContact CB-CG1 3.69Å
78V98.9Very high97.6Very high21 Ų2132.1 Ų32.113%0.12716%0.164CC..EExtended strand (participates in β ladder)trans-128.3131-175.1-173.50000110.4T30 L32 R72 E75T30-V78 WeakPolarHBondContact O-CA 3.48Å; L32-V78 HydrophobicContact CD1-CG1 3.7Å; L32-V78 HydrophobicContact CG-CG1 3.83Å; R72-V78 HydrophobicContact CG-CB 4.23Å; R72-V78 HydrophobicContact CG-CG1 4.04Å; R72-V78 HydrophobicContact CG-CG2 4.48Å; E75-V78 HydrophobicContact CB-CG2 3.65Å; E75-V78 WeakPolarHBondContact O-CG2 3.4Å
79L98.9Very high96.8Very high4 Ų432.3 Ų32.32%0.02117%0.165CC..EExtended strand (participates in β ladder)trans-115.1132.9165.1-71.2173.5000109.2L29 T30 L32 L81 D111 L164 V166 V171 I173 I216L29-L79 HydrophobicContact CD1-CD1 4.17Å; L29-L79 HydrophobicContact CD1-CG 4.14Å; L29-L79 HydrophobicContact CD2-CD1 4.27Å; T30-L79 PolarHBondContact O-N 3.45Å; L32-L79 PolarHBondContact N-O 2.99Å; L79-L81 HydrophobicContact CB-CD2 4.13Å; L79-L81 HydrophobicContact CB-CG 4.26Å; L79-D111 HydrophobicContact CD2-CB 3.8Å; L79-L164 HydrophobicContact CD2-CD1 4Å; L79-V166 HydrophobicContact CD1-CG2 4.14Å; L79-V166 HydrophobicContact CD2-CG2 3.79Å; L79-V166 HydrophobicContact CG-CG2 3.98Å; L79-V171 HydrophobicContact CD1-CB 4.23Å; L79-V171 HydrophobicContact CD1-CG1 4.08Å; L79-V171 HydrophobicContact CD1-CG2 4.44Å; L79-I173 HydrophobicContact CD1-CD1 4.27Å; L79-I216 HydrophobicContact CD1-CD1 4.05Å
80L98.9Very high96.3Very high0 Ų031.6 Ų31.60%016%0.163CC..EExtended strand (participates in β ladder)trans-105.9111.1169.317864.6000109.5L32 V68 L108 Y110 D111 L287L32-L80 HydrophobicContact CB-CB 4.37Å; L32-L80 HydrophobicContact CB-CD1 3.6Å; L32-L80 CarbonylContact O-C 3.49Å; L32-L80 WeakPolarHBondContact O-CA 3.43Å; V68-L80 HydrophobicContact CG1-CD2 4.01Å; V68-L80 HydrophobicContact CG2-CD1 4.14Å; V68-L80 HydrophobicContact CG2-CD2 4.14Å; L80-L108 HydrophobicContact CD2-CB 4.31Å; L80-Y110 HydrophobicContact CD1-CD1 4.41Å; L80-Y110 HydrophobicContact CD1-CE1 3.91Å; L80-Y110 HydrophobicContact CD2-CD1 4.03Å; L80-Y110 HydrophobicContact CD2-CD2 3.92Å; L80-Y110 HydrophobicContact CD2-CE1 3.99Å; L80-Y110 HydrophobicContact CD2-CE2 3.92Å; L80-Y110 HydrophobicContact CD2-CG 3.98Å; L80-Y110 HydrophobicContact CG-CD1 3.62Å; L80-Y110 HydrophobicContact CG-CD2 4.43Å; L80-Y110 HydrophobicContact CG-CE1 3.6Å; L80-Y110 HydrophobicContact CG-CE2 4.46Å; L80-Y110 HydrophobicContact CG-CG 4.05Å; L80-D111 PolarHBondContact N-OD2 2.97Å; L80-D111 PolarHBondContact O-N 3.45Å; L80-L287 HydrophobicContact CD1-CD1 4.24Å
81L99Very high95.8Very high0 Ų027.9 Ų27.90%015%0.146CC..EExtended strand (participates in β ladder)trans-114.6146.7-173.1-53.2-177.1000111.1I31 L32 H33 T34 L79 D111 A112 I173 I216 L218I31-L81 HydrophobicContact CG2-CD1 3.9Å; I31-L81 HydrophobicContact CG2-CG 4.37Å; L32-L81 PolarHBondContact O-N 3.18Å; H33-L81 CarbonylContact C-O 3.56Å; H33-L81 WeakPolarHBondContact CA-O 3.44Å; H33-L81 HydrophobicContact CB-CB 4.49Å; T34-L81 PolarHBondContact N-O 2.92Å; L79-L81 HydrophobicContact CB-CD2 4.13Å; L79-L81 HydrophobicContact CB-CG 4.26Å; L81-D111 HydrophobicContact CD2-CB 4.36Å; L81-A112 WeakPolarHBondContact CA-O 3.36Å; L81-A112 HydrophobicContact CD2-CB 4.03Å; L81-I173 HydrophobicContact CD1-CD1 4.41Å; L81-I173 HydrophobicContact CD2-CD1 3.63Å; L81-I216 HydrophobicContact CD1-CD1 4.14Å; L81-I216 HydrophobicContact CD1-CG2 4.18Å; L81-L218 HydrophobicContact CB-CD1 3.94Å; L81-L218 HydrophobicContact CB-CD2 4.04Å; L81-L218 HydrophobicContact CD1-CD1 4.45Å; L81-L218 HydrophobicContact CD2-CD2 4.44Å
82D98.9Very high95.5Very high0 Ų027.3 Ų27.30%014%0.143CC..EExtended strand (participates in β ladder)trans-119.7130.9170.1-170.9-97.8000110.7T34 G84 Q86 M105 Y110 A112 M113 A114T34-D82 CarbonylContact O-C 3.42Å; T34-D82 WeakPolarHBondContact O-CA 3.37Å; T34-D82 PolarHBondContact OG1-OD2 3.21Å; D82-G84 VanDerWaalsContact C-N 3.35Å; D82-G84 WeakPolarHBondContact OD1-CA 3.46Å; D82-G84 PolarHBondContact OD1-N 3.1Å; D82-Q86 PolarHBondContact OD2-NE2 2.98Å; D82-M105 HydrophobicContact CB-CE 3.67Å; D82-Y110 HydrophobicContact CB-CD1 3.86Å; D82-Y110 HydrophobicContact CB-CE1 3.71Å; D82-A112 PolarHBondContact N-O 3.06Å; D82-M113 HydrophobicContact CB-CB 4.18Å; D82-M113 HydrophobicContact CB-CG 4.04Å; D82-M113 CarbonylContact O-C 3.59Å; D82-M113 VanDerWaalsContact O-CA 3.29Å; D82-M113 WeakPolarHBondContact O-CA 3.16Å; D82-A114 PolarHBondContact O-N 3.39Å
83A98.9Very high95.2Very high0 Ų025 Ų250%013%0.134CC..  trans-97.226.7-177.900000112.9T34 N35 L218 H220 G241T34-A83 PolarHBondContact O-N 3.38Å; N35-A83 HydrophobicContact CB-CB 3.88Å; A83-L218 HydrophobicContact CB-CD1 3.91Å; A83-H220 VanDerWaalsContact O-CB 3.31Å; A83-H220 WeakPolarHBondContact O-CB 3.48Å; A83-H220 PolarHBondContact O-ND1 3.04Å; A83-G241 VanDerWaalsContact CB-C 3.48Å; A83-G241 WeakPolarHBondContact CB-O 3.45Å
84G96.3Very high94.6Very high0 Ų017.8 Ų17.80%011%0.114CC..SBendtrans92.8174.1172.100000114.7D36 D82 A114D36-G84 PolarHBondContact N-O 2.48Å; D82-G84 VanDerWaalsContact C-N 3.35Å; D82-G84 WeakPolarHBondContact OD1-CA 3.46Å; D82-G84 PolarHBondContact OD1-N 3.1Å; G84-A114 WeakPolarHBondContact CA-O 3.41Å; G84-A114 PolarHBondContact N-O 2.94Å
85D95.3Very high94.2Very high2 Ų215.3 Ų15.31%0.0119%0.091CC..  trans60.947.1-177.2-77.47000113.7D36 V37 H38 G116 N117 H118 E119 H220D36-D85 CarbonylContact C-O 3.58Å; V37-D85 PolarHBondContact N-O 3.14Å; V37-D85 VanDerWaalsContact N-O 3.16Å; H38-D85 IonicContact CE1-OD2 3.97Å; H38-D85 PolarHBondContact CE1-OD2 2.71Å; H38-D85 PolarHBondContact N-O 2.93Å; D85-G116 WeakPolarHBondContact OD1-CA 3.43Å; D85-N117 PolarHBondContact OD1-N 3.08Å; D85-H118 WeakPolarHBondContact OD1-CB 3.35Å; D85-H118 IonicContact OD1-CD2 2.75Å; D85-H118 PolarHBondContact OD1-N 2.72Å; D85-H118 IonicContact OD2-CD2 2.96Å; D85-H118 PolarHBondContact OD2-CD2 3.48Å; D85-H118 VanDerWaalsContact OD2-CD2 3.23Å; D85-E119 WeakPolarHBondContact CA-OE1 3.35Å; D85-E119 PolarHBondContact N-OE1 3.13Å; D85-E119 PolarHBondContact N-OE2 3.33Å; D85-H220 VanDerWaalsContact CB-CE1 3.43Å; D85-H220 WeakPolarHBondContact CB-CE1 3.34Å; D85-H220 IonicContact OD1-CD2 2.99Å; D85-H220 IonicContact OD1-CE1 3.69Å; D85-H220 IonicContact OD1-NE2 2.81Å; D85-H220 PolarHBondContact OD1-NE2 3.05Å; D85-H220 IonicContact OD2-CE1 3.75Å; D85-H220 PolarHBondContact OD2-CE1 2.68Å; D85-H220 VanDerWaalsContact OD2-CE1 3.24Å; D85-H220 IonicContact OD2-NE2 2.73Å; D85-H220 PolarHBondContact OD2-NE2 3.17Å
86Q97.8Very high94.1Very high9 Ų915.3 Ų15.34%0.0429%0.089CC..  trans-74.2-39.5162.7-73.4-78-13.800110.4S39 D82 V101 M105 M113 E119S39-Q86 PolarHBondContact N-O 3.43Å; S39-Q86 PolarHBondContact OG-O 3.08Å; D82-Q86 PolarHBondContact OD2-NE2 2.98Å; Q86-V101 HydrophobicContact CB-CB 4.43Å; Q86-V101 HydrophobicContact CB-CG1 3.52Å; Q86-V101 HydrophobicContact CB-CG2 3.98Å; Q86-V101 HydrophobicContact CG-CG1 4.04Å; Q86-M105 HydrophobicContact CG-CE 4.34Å; Q86-M105 HydrophobicContact CG-SD 3.74Å; Q86-M113 HydrophobicContact CB-CE 4.08Å; Q86-M113 HydrophobicContact CG-CE 3.89Å; Q86-E119 PolarHBondContact N-OE1 2.85Å
87Y95.3Very high93.9Very high0 Ų014.9 Ų14.90%08%0.077CC..SBendtrans-63158.9176.3-8428.7000111.7H38 F93 G98 V101 H118 E119 G126 L131H38-Y87 PolarHBondContact ND1-O 2.95Å; Y87-F93 HydrophobicContact CD1-CD2 4.42Å; Y87-F93 AromaticContact CD1-CE2 3.94Å; Y87-F93 HydrophobicContact CD1-CE2 3.94Å; Y87-F93 HydrophobicContact CD2-CD2 4.37Å; Y87-F93 AromaticContact CD2-CE2 3.24Å; Y87-F93 HydrophobicContact CD2-CE2 3.24Å; Y87-F93 AromaticContact CD2-CZ 3.46Å; Y87-F93 HydrophobicContact CD2-CZ 3.46Å; Y87-F93 VanDerWaalsContact CD2-CZ 3.46Å; Y87-F93 HydrophobicContact CE1-CE2 4.32Å; Y87-F93 AromaticContact CE2-CE2 3.71Å; Y87-F93 HydrophobicContact CE2-CE2 3.71Å; Y87-F93 HydrophobicContact CE2-CZ 4.11Å; Y87-F93 HydrophobicContact CG-CD2 4.1Å; Y87-F93 AromaticContact CG-CE2 3.36Å; Y87-F93 HydrophobicContact CG-CE2 3.36Å; Y87-F93 AromaticContact CG-CZ 3.86Å; Y87-F93 HydrophobicContact CG-CZ 3.86Å; Y87-G98 VanDerWaalsContact CE1-CA 3.44Å; Y87-V101 HydrophobicContact CD1-CB 4.39Å; Y87-V101 HydrophobicContact CD1-CG1 4.48Å; Y87-V101 HydrophobicContact CD1-CG2 4.03Å; Y87-V101 HydrophobicContact CE1-CB 4.22Å; Y87-V101 HydrophobicContact CE1-CG1 4.42Å; Y87-V101 HydrophobicContact CE1-CG2 4.29Å; Y87-H118 VanDerWaalsContact CB-O 3.27Å; Y87-H118 WeakPolarHBondContact CB-O 3.34Å; Y87-E119 WeakPolarHBondContact CB-OE1 3.19Å; Y87-E119 HydrophobicContact CD1-CG 4.32Å; Y87-E119 HydrophobicContact CD2-CB 4.47Å; Y87-E119 HydrophobicContact CD2-CG 4.47Å; Y87-E119 HydrophobicContact CG-CG 4.18Å; Y87-E119 PolarHBondContact N-OE1 2.82Å; Y87-G126 PolarHBondContact OH-O 2.84Å; Y87-G126 VanDerWaalsContact OH-O 3.11Å; Y87-L131 HydrophobicContact CD1-CD2 4.49Å; Y87-L131 HydrophobicContact CE1-CB 4.05Å; Y87-L131 HydrophobicContact CE1-CD2 3.82Å; Y87-L131 HydrophobicContact CE1-CG 4.4Å; Y87-L131 WeakPolarHBondContact OH-CB 3.44Å
88Q87.1Confident93.7Very high7 Ų713.9 Ų13.93%0.0337%0.071CC..SBendtrans66.4155.1177.9-163.956.1-82.800115.2H38 S39 F93 H118 D121 P416 F417H38-Q88 CarbonylContact C-O 3.58Å; H38-Q88 WeakPolarHBondContact CA-O 3.33Å; H38-Q88 WeakPolarHBondContact CB-O 3.38Å; S39-Q88 WeakPolarHBondContact CB-O 3.39Å; S39-Q88 PolarHBondContact N-O 3.41Å; S39-Q88 PolarHBondContact OG-N 2.87Å; S39-Q88 PolarHBondContact OG-O 2.83Å; Q88-F93 VanDerWaalsContact CA-CD1 3.47Å; Q88-F93 HydrophobicContact CB-CD1 4.28Å; Q88-F93 HydrophobicContact CB-CE1 4.33Å; Q88-H118 HydrophobicContact CB-CB 3.95Å; Q88-D121 WeakPolarHBondContact CB-OD2 3.42Å; Q88-D121 VanDerWaalsContact CG-OD2 3.26Å; Q88-D121 WeakPolarHBondContact CG-OD2 3.45Å; Q88-D121 PolarHBondContact NE2-OD2 2.78Å; Q88-P416 HydrophobicContact CG-CG 4.24Å; Q88-P416 VanDerWaalsContact OE1-CB 3.29Å; Q88-P416 PolarHBondContact OE1-O 2.9Å; Q88-F417 HydrophobicContact CG-CD1 4.18Å; Q88-F417 HydrophobicContact CG-CE1 4.03Å
89G83.8Confident93.7Very high3 Ų313.9 Ų13.93%0.0317%0.074CC..SBendtrans120.2-19.7161.800000116.8R40R40-G89 VanDerWaalsContact NH1-C 3.34Å; R40-G89 PolarHBondContact NH1-O 3.15Å
90T87.6Confident93.6Very high17 Ų1713.7 Ų13.710%0.1047%0.073CC..SBendtrans-142.9173.7172.773.20000111.5S39 W92 F93 T94S39-T90 WeakPolarHBondContact CB-OG1 3.38Å; S39-T90 VanDerWaalsContact O-CG2 3.31Å; S39-T90 WeakPolarHBondContact O-CG2 3.49Å; S39-T90 PolarHBondContact O-OG1 2.93Å; T90-W92 PolarHBondContact O-N 2.93Å; T90-W92 VanDerWaalsContact O-N 3.09Å; T90-W92 WeakPolarHBondContact OG1-CB 3.45Å; T90-W92 PolarHBondContact OG1-N 2.91Å; T90-F93 PolarHBondContact O-N 2.89Å; T90-T94 PolarHBondContact O-N 2.97Å; T90-T94 PolarHBondContact O-OG1 2.89Å
91I88.8Confident93.6Very high4 Ų413.8 Ų13.82%0.0217%0.073CC..Hα-helixtrans-57.9-20.7173.160.9166.9000114.1T94 V95 L331 E409 A412I91-T94 PolarHBondContact O-N 2.86Å; I91-V95 WeakPolarHBondContact O-CG2 3.46Å; I91-V95 PolarHBondContact O-N 2.95Å; I91-L331 HydrophobicContact CD1-CB 3.74Å; I91-L331 HydrophobicContact CD1-CD1 4.16Å; I91-L331 HydrophobicContact CD1-CD2 4.43Å; I91-L331 HydrophobicContact CD1-CG 4.33Å; I91-L331 HydrophobicContact CG1-CD1 4.24Å; I91-E409 HydrophobicContact CD1-CB 4.15Å; I91-E409 HydrophobicContact CD1-CG 3.73Å; I91-E409 HydrophobicContact CG1-CG 4.17Å; I91-E409 HydrophobicContact CG2-CB 4.39Å; I91-E409 HydrophobicContact CG2-CG 4.36Å; I91-A412 HydrophobicContact CG2-CB 3.41Å; I91-A412 VanDerWaalsContact CG2-CB 3.41Å
92W92.3Very high93.6Very high4 Ų413.8 Ų13.82%0.0157%0.073CC..Hα-helixtrans-57.4-52.8175.7-77.186.5000110L41 E42 T90 T94 V95 Y96 E100 F104 I324 W327 R328 L331L41-W92 HydrophobicContact CB-CD2 4.04Å; L41-W92 HydrophobicContact CB-CE3 4.35Å; L41-W92 HydrophobicContact CB-CG 4.34Å; L41-W92 HydrophobicContact CD2-CB 4.36Å; L41-W92 HydrophobicContact CD2-CG 4.5Å; L41-W92 HydrophobicContact CG-CD2 4.3Å; L41-W92 HydrophobicContact CG-CE3 4.28Å; E42-W92 HydrophobicContact CG-CZ2 3.75Å; E42-W92 PolarHBondContact OE1-NE1 3.42Å; T90-W92 PolarHBondContact O-N 2.93Å; T90-W92 VanDerWaalsContact O-N 3.09Å; T90-W92 WeakPolarHBondContact OG1-CB 3.45Å; T90-W92 PolarHBondContact OG1-N 2.91Å; W92-T94 PolarHBondContact O-N 3.15Å; W92-V95 PolarHBondContact O-N 3.21Å; W92-Y96 AromaticContact CE3-CD2 3.8Å; W92-Y96 HydrophobicContact CE3-CD2 3.8Å; W92-Y96 AromaticContact CE3-CE2 3.84Å; W92-Y96 HydrophobicContact CE3-CE2 3.84Å; W92-Y96 HydrophobicContact CZ3-CD2 4.31Å; W92-Y96 AromaticContact CZ3-CE2 3.97Å; W92-Y96 HydrophobicContact CZ3-CE2 3.97Å; W92-Y96 VanDerWaalsContact O-CB 3.31Å; W92-Y96 WeakPolarHBondContact O-CB 3.38Å; W92-Y96 WeakPolarHBondContact O-CD2 3.34Å; W92-Y96 PolarHBondContact O-N 3.22Å; W92-E100 HydrophobicContact CB-CG 4.34Å; W92-E100 HydrophobicContact CE3-CB 4.2Å; W92-E100 HydrophobicContact CE3-CG 4.42Å; W92-F104 HydrophobicContact CZ3-CE2 4.32Å; W92-I324 HydrophobicContact CH2-CG2 3.88Å; W92-I324 WeakPolarHBondContact CH2-O 3.45Å; W92-I324 HydrophobicContact CZ2-CG2 3.85Å; W92-W327 HydrophobicContact CH2-CB 3.72Å; W92-W327 HydrophobicContact CZ3-CB 3.5Å; W92-W327 VanDerWaalsContact CZ3-CB 3.5Å; W92-W327 HydrophobicContact CZ3-CG 4.36Å; W92-R328 HydrophobicContact CH2-CB 4.45Å; W92-R328 HydrophobicContact CZ2-CB 4.32Å; W92-L331 HydrophobicContact CD2-CD1 3.5Å; W92-L331 VanDerWaalsContact CD2-CD1 3.5Å; W92-L331 VanDerWaalsContact CE2-CD1 3.44Å; W92-L331 HydrophobicContact CE3-CD1 3.95Å; W92-L331 HydrophobicContact CG-CD1 3.83Å; W92-L331 HydrophobicContact CH2-CD1 4.28Å; W92-L331 HydrophobicContact CZ2-CD1 3.86Å; W92-L331 HydrophobicContact CZ3-CD1 4.33Å
93F91.4Very high93.6Very high3 Ų316.6 Ų16.61%0.0139%0.086CC..Hα-helixtrans-67.1-37.5177.1-177.1-112000112.8S39 Y87 Q88 T90 V95 K97 E100 D121 N122S39-F93 WeakPolarHBondContact OG-CB 3.18Å; Y87-F93 HydrophobicContact CD1-CD2 4.42Å; Y87-F93 AromaticContact CD1-CE2 3.94Å; Y87-F93 HydrophobicContact CD1-CE2 3.94Å; Y87-F93 HydrophobicContact CD2-CD2 4.37Å; Y87-F93 AromaticContact CD2-CE2 3.24Å; Y87-F93 HydrophobicContact CD2-CE2 3.24Å; Y87-F93 AromaticContact CD2-CZ 3.46Å; Y87-F93 HydrophobicContact CD2-CZ 3.46Å; Y87-F93 VanDerWaalsContact CD2-CZ 3.46Å; Y87-F93 HydrophobicContact CE1-CE2 4.32Å; Y87-F93 AromaticContact CE2-CE2 3.71Å; Y87-F93 HydrophobicContact CE2-CE2 3.71Å; Y87-F93 HydrophobicContact CE2-CZ 4.11Å; Y87-F93 HydrophobicContact CG-CD2 4.1Å; Y87-F93 AromaticContact CG-CE2 3.36Å; Y87-F93 HydrophobicContact CG-CE2 3.36Å; Y87-F93 AromaticContact CG-CZ 3.86Å; Y87-F93 HydrophobicContact CG-CZ 3.86Å; Q88-F93 VanDerWaalsContact CA-CD1 3.47Å; Q88-F93 HydrophobicContact CB-CD1 4.28Å; Q88-F93 HydrophobicContact CB-CE1 4.33Å; T90-F93 PolarHBondContact O-N 2.89Å; F93-V95 PolarHBondContact O-N 2.83Å; F93-K97 VanDerWaalsContact O-CA 3.24Å; F93-K97 WeakPolarHBondContact O-CA 3.5Å; F93-K97 PolarHBondContact O-N 2.99Å; F93-E100 WeakPolarHBondContact CA-OE1 3.12Å; F93-D121 HydrophobicContact CE1-CB 4.37Å; F93-D121 HydrophobicContact CZ-CB 4.49Å; F93-N122 WeakPolarHBondContact CZ-ND2 3.48Å
94T86.4Confident93.6Very high61 Ų6116.7 Ų16.737%0.3749%0.087SC..Hα-helixtrans-56.7-39.6177.1-49.30000111.8T90 I91 W92 K97T90-T94 PolarHBondContact O-N 2.97Å; T90-T94 PolarHBondContact O-OG1 2.89Å; I91-T94 PolarHBondContact O-N 2.86Å; W92-T94 PolarHBondContact O-N 3.15Å; T94-K97 WeakPolarHBondContact O-CE 3.35Å
95V90.4Very high93.7Very high25 Ų2517 Ų1715%0.1529%0.088CC..Hα-helixtrans-93.7-36.6-174.9173.90000113.3I91 W92 F93 K330 L331 Y334I91-V95 WeakPolarHBondContact O-CG2 3.46Å; I91-V95 PolarHBondContact O-N 2.95Å; W92-V95 PolarHBondContact O-N 3.21Å; F93-V95 PolarHBondContact O-N 2.83Å; V95-K330 HydrophobicContact CG1-CD 3.68Å; V95-K330 HydrophobicContact CG1-CG 4.04Å; V95-L331 HydrophobicContact CB-CD2 3.49Å; V95-L331 VanDerWaalsContact CB-CD2 3.49Å; V95-L331 HydrophobicContact CG1-CD2 3.73Å; V95-L331 HydrophobicContact CG2-CD2 3.52Å; V95-Y334 HydrophobicContact CG2-CD2 4.38Å; V95-Y334 HydrophobicContact CG2-CE2 3.78Å
96Y94.6Very high93.9Very high34 Ų3418.1 Ų18.113%0.1339%0.094CC..Hα-helixtrans-103.1-13.3-173.9-67.5-66.2000114.5W92 G98 A99 E100 W327 K330 L331W92-Y96 AromaticContact CE3-CD2 3.8Å; W92-Y96 HydrophobicContact CE3-CD2 3.8Å; W92-Y96 AromaticContact CE3-CE2 3.84Å; W92-Y96 HydrophobicContact CE3-CE2 3.84Å; W92-Y96 HydrophobicContact CZ3-CD2 4.31Å; W92-Y96 AromaticContact CZ3-CE2 3.97Å; W92-Y96 HydrophobicContact CZ3-CE2 3.97Å; W92-Y96 VanDerWaalsContact O-CB 3.31Å; W92-Y96 WeakPolarHBondContact O-CB 3.38Å; W92-Y96 WeakPolarHBondContact O-CD2 3.34Å; W92-Y96 PolarHBondContact O-N 3.22Å; Y96-G98 PolarHBondContact O-N 3.45Å; Y96-G98 VanDerWaalsContact O-N 3.1Å; Y96-A99 WeakPolarHBondContact O-CB 3.16Å; Y96-A99 PolarHBondContact O-N 3.36Å; Y96-E100 WeakPolarHBondContact CB-OE2 3.24Å; Y96-E100 HydrophobicContact CD2-CB 4.4Å; Y96-E100 HydrophobicContact CG-CB 4.35Å; Y96-W327 AromaticContact CD1-CE3 3.54Å; Y96-W327 HydrophobicContact CD1-CE3 3.54Å; Y96-W327 AromaticContact CD1-CZ3 3.52Å; Y96-W327 HydrophobicContact CD1-CZ3 3.52Å; Y96-W327 HydrophobicContact CD2-CE3 4.1Å; Y96-W327 HydrophobicContact CE1-CD2 4.35Å; Y96-W327 AromaticContact CE1-CE3 3.36Å; Y96-W327 HydrophobicContact CE1-CE3 3.36Å; Y96-W327 AromaticContact CE1-CZ3 3.76Å; Y96-W327 HydrophobicContact CE1-CZ3 3.76Å; Y96-W327 HydrophobicContact CE2-CB 4.32Å; Y96-W327 AromaticContact CE2-CE3 3.95Å; Y96-W327 HydrophobicContact CE2-CE3 3.95Å; Y96-W327 AromaticContact CG-CE3 3.91Å; Y96-W327 HydrophobicContact CG-CE3 3.91Å; Y96-W327 AromaticContact CG-CZ3 3.98Å; Y96-W327 HydrophobicContact CG-CZ3 3.98Å; Y96-W327 AromaticContact CZ-CE3 3.58Å; Y96-W327 WeakPolarHBondContact OH-CA 3.49Å; Y96-W327 PolarHBondContact OH-O 2.93Å; Y96-K330 HydrophobicContact CE1-CD 4.16Å; Y96-K330 WeakPolarHBondContact OH-CB 3.41Å; Y96-L331 HydrophobicContact CD2-CD2 4.36Å; Y96-L331 HydrophobicContact CE2-CD1 4.11Å; Y96-L331 HydrophobicContact CE2-CD2 3.84Å; Y96-L331 HydrophobicContact CE2-CG 4.03Å
97K92.6Very high93.9Very high97 Ų9719.2 Ų19.242%0.42211%0.105SC..THydrogen-bonded Turntrans5726.9168-57.4-68.3-172.3-176.30114.2F93 T94 P130F93-K97 VanDerWaalsContact O-CA 3.24Å; F93-K97 WeakPolarHBondContact O-CA 3.5Å; F93-K97 PolarHBondContact O-N 2.99Å; T94-K97 WeakPolarHBondContact O-CE 3.35Å; K97-P130 WeakPolarHBondContact O-CD 3.31Å
98G94.7Very high94.1Very high0 Ų019.3 Ų19.30%011%0.105CC..THydrogen-bonded Turntrans104.3-9.6-179.800000114.6Y87 Y96 E100 V101 A102Y87-G98 VanDerWaalsContact CE1-CA 3.44Å; Y96-G98 PolarHBondContact O-N 3.45Å; Y96-G98 VanDerWaalsContact O-N 3.1Å; G98-E100 WeakPolarHBondContact CA-OE2 3.49Å; G98-E100 PolarHBondContact N-OE2 2.8Å; G98-E100 PolarHBondContact O-N 2.86Å; G98-V101 WeakPolarHBondContact O-CB 3.16Å; G98-V101 PolarHBondContact O-N 3.01Å; G98-V101 VanDerWaalsContact O-N 3.08Å; G98-A102 PolarHBondContact O-N 3.36Å; G98-A102 VanDerWaalsContact O-N 3.07Å
99A98.2Very high94.6Very high22 Ų2225.6 Ų25.618%0.18213%0.129CC..Hα-helixtrans-66.4-33.7178.400000110.9Y96 V101 H103 P130 W327Y96-A99 WeakPolarHBondContact O-CB 3.16Å; Y96-A99 PolarHBondContact O-N 3.36Å; A99-V101 VanDerWaalsContact C-N 3.31Å; A99-H103 WeakPolarHBondContact O-CB 3.37Å; A99-H103 PolarHBondContact O-N 2.67Å; A99-P130 VanDerWaalsContact CA-CG 3.49Å; A99-P130 HydrophobicContact CB-CB 4.23Å; A99-P130 HydrophobicContact CB-CG 3.9Å; A99-W327 HydrophobicContact CB-CZ3 4.47Å
100E98Very high95.3Very high0 Ų026 Ų260%013%0.13CC..Hα-helixtrans-62-39.4171.578.9-70.5-175.300111.6L41 W92 F93 Y96 G98 F104 W327L41-E100 HydrophobicContact CD2-CG 3.94Å; L41-E100 HydrophobicContact CG-CG 4.17Å; W92-E100 HydrophobicContact CB-CG 4.34Å; W92-E100 HydrophobicContact CE3-CB 4.2Å; W92-E100 HydrophobicContact CE3-CG 4.42Å; F93-E100 WeakPolarHBondContact CA-OE1 3.12Å; Y96-E100 WeakPolarHBondContact CB-OE2 3.24Å; Y96-E100 HydrophobicContact CD2-CB 4.4Å; Y96-E100 HydrophobicContact CG-CB 4.35Å; G98-E100 WeakPolarHBondContact CA-OE2 3.49Å; G98-E100 PolarHBondContact N-OE2 2.8Å; G98-E100 PolarHBondContact O-N 2.86Å; E100-F104 HydrophobicContact CB-CD2 4.44Å; E100-F104 WeakPolarHBondContact O-CD2 3.28Å; E100-F104 PolarHBondContact O-N 2.86Å; E100-W327 HydrophobicContact CB-CE3 4.37Å; E100-W327 HydrophobicContact CB-CZ3 4.23Å
101V98.3Very high95.9Very high1 Ų127.5 Ų27.51%0.00614%0.137CC..Hα-helixtrans-65.4-54.1179.6172.70000109.5Q86 Y87 G98 A99 H103 F104 M105 L131Q86-V101 HydrophobicContact CB-CB 4.43Å; Q86-V101 HydrophobicContact CB-CG1 3.52Å; Q86-V101 HydrophobicContact CB-CG2 3.98Å; Q86-V101 HydrophobicContact CG-CG1 4.04Å; Y87-V101 HydrophobicContact CD1-CB 4.39Å; Y87-V101 HydrophobicContact CD1-CG1 4.48Å; Y87-V101 HydrophobicContact CD1-CG2 4.03Å; Y87-V101 HydrophobicContact CE1-CB 4.22Å; Y87-V101 HydrophobicContact CE1-CG1 4.42Å; Y87-V101 HydrophobicContact CE1-CG2 4.29Å; G98-V101 WeakPolarHBondContact O-CB 3.16Å; G98-V101 PolarHBondContact O-N 3.01Å; G98-V101 VanDerWaalsContact O-N 3.08Å; A99-V101 VanDerWaalsContact C-N 3.31Å; V101-H103 VanDerWaalsContact C-N 3.31Å; V101-H103 PolarHBondContact O-N 2.94Å; V101-F104 PolarHBondContact O-N 3.09Å; V101-M105 HydrophobicContact CG1-CG 4.17Å; V101-M105 HydrophobicContact CG1-SD 3.47Å; V101-M105 WeakPolarHBondContact CG1-SD 3.36Å; V101-M105 VanDerWaalsContact O-CB 3.24Å; V101-M105 WeakPolarHBondContact O-CB 3.31Å; V101-M105 VanDerWaalsContact O-CG 3.24Å; V101-M105 WeakPolarHBondContact O-CG 3.4Å; V101-M105 PolarHBondContact O-N 3.32Å; V101-L131 HydrophobicContact CG1-CD1 4.12Å
102A98.5Very high96.3Very high0 Ų027.3 Ų27.30%014%0.136CC..Hα-helixtrans-56.4-46.2178.100000111.4G98 N106 L131 E134G98-A102 PolarHBondContact O-N 3.36Å; G98-A102 VanDerWaalsContact O-N 3.07Å; A102-N106 WeakPolarHBondContact O-CB 3.19Å; A102-N106 PolarHBondContact O-N 3.45Å; A102-N106 PolarHBondContact O-ND2 3.31Å; A102-L131 HydrophobicContact CB-CD1 4.32Å; A102-E134 HydrophobicContact CB-CB 3.8Å
103H98.8Very high96.7Very high60 Ų6027.1 Ų27.128%0.27814%0.135SC..Hα-helixtrans-60.8-54.4-179.5179.178000113A99 V101 N106 A107 D323 W327A99-H103 WeakPolarHBondContact O-CB 3.37Å; A99-H103 PolarHBondContact O-N 2.67Å; V101-H103 VanDerWaalsContact C-N 3.31Å; V101-H103 PolarHBondContact O-N 2.94Å; H103-N106 WeakPolarHBondContact O-CB 3.31Å; H103-N106 PolarHBondContact O-N 3.39Å; H103-A107 PolarHBondContact O-N 2.83Å; H103-D323 IonicContact CD2-OD2 3.84Å; H103-D323 IonicContact CE1-OD2 3.41Å; H103-D323 PolarHBondContact CE1-OD2 3.47Å; H103-D323 IonicContact NE2-OD1 3.23Å; H103-D323 IonicContact NE2-OD2 3.98Å; H103-D323 PolarHBondContact NE2-OD2 2.87Å; H103-W327 HydrophobicContact CB-CH2 4.04Å; H103-W327 HydrophobicContact CB-CZ2 3.97Å; H103-W327 AromaticContact CD2-CZ2 3.8Å; H103-W327 AromaticContact CG-CZ2 3.62Å; H103-W327 AromaticContact ND1-CZ2 3.94Å; H103-W327 AromaticContact NE2-NE1 3.91Å
104F98.8Very high97Very high2 Ų227 Ų271%0.00913%0.134CC..Hα-helixtrans-76.1-33.8-175-72.9-67.6000112.6L41 V61 W92 E100 V101 N106 A107 L108 I320 D323 I324L41-F104 HydrophobicContact CD1-CB 3.95Å; L41-F104 HydrophobicContact CD1-CD2 3.41Å; L41-F104 VanDerWaalsContact CD1-CD2 3.41Å; L41-F104 HydrophobicContact CD1-CE2 4.19Å; L41-F104 HydrophobicContact CD1-CG 3.88Å; L41-F104 HydrophobicContact CG-CD2 4.22Å; V61-F104 HydrophobicContact CG1-CB 4.3Å; V61-F104 HydrophobicContact CG1-CD1 3.88Å; V61-F104 HydrophobicContact CG1-CE1 4.38Å; V61-F104 HydrophobicContact CG1-CG 4.01Å; V61-F104 HydrophobicContact CG2-CB 3.94Å; W92-F104 HydrophobicContact CZ3-CE2 4.32Å; E100-F104 HydrophobicContact CB-CD2 4.44Å; E100-F104 WeakPolarHBondContact O-CD2 3.28Å; E100-F104 PolarHBondContact O-N 2.86Å; V101-F104 PolarHBondContact O-N 3.09Å; F104-N106 VanDerWaalsContact C-N 3.32Å; F104-N106 PolarHBondContact O-N 3.36Å; F104-A107 WeakPolarHBondContact O-CB 3.17Å; F104-A107 PolarHBondContact O-N 3.29Å; F104-L108 WeakPolarHBondContact O-CD1 3.48Å; F104-L108 PolarHBondContact O-N 3.15Å; F104-I320 HydrophobicContact CD1-CG2 4.18Å; F104-I320 HydrophobicContact CE1-CG2 4.2Å; F104-D323 HydrophobicContact CE1-CB 4.25Å; F104-I324 HydrophobicContact CE1-CG1 3.74Å; F104-I324 HydrophobicContact CE2-CG1 4.46Å; F104-I324 HydrophobicContact CZ-CB 4.4Å; F104-I324 HydrophobicContact CZ-CG1 3.68Å
105M98.8Very high97.6Very high5 Ų524.1 Ų24.13%0.02512%0.117CC..Hα-helixtrans-65.3-37.5171.9-67.8-176.177.700111.6D82 Q86 V101 A107 L108 R109 Y110 M113 F137D82-M105 HydrophobicContact CB-CE 3.67Å; Q86-M105 HydrophobicContact CG-CE 4.34Å; Q86-M105 HydrophobicContact CG-SD 3.74Å; V101-M105 HydrophobicContact CG1-CG 4.17Å; V101-M105 HydrophobicContact CG1-SD 3.47Å; V101-M105 WeakPolarHBondContact CG1-SD 3.36Å; V101-M105 VanDerWaalsContact O-CB 3.24Å; V101-M105 WeakPolarHBondContact O-CB 3.31Å; V101-M105 VanDerWaalsContact O-CG 3.24Å; V101-M105 WeakPolarHBondContact O-CG 3.4Å; V101-M105 PolarHBondContact O-N 3.32Å; M105-A107 VanDerWaalsContact C-N 3.35Å; M105-L108 CarbonylContact O-C 3.53Å; M105-L108 PolarHBondContact O-N 3.44Å; M105-R109 PolarHBondContact O-N 3.1Å; M105-Y110 HydrophobicContact CB-CD2 3.69Å; M105-Y110 HydrophobicContact CB-CE2 4.18Å; M105-Y110 HydrophobicContact CB-CG 4.43Å; M105-Y110 HydrophobicContact CE-CD1 3.8Å; M105-Y110 HydrophobicContact CE-CD2 3.8Å; M105-Y110 HydrophobicContact CE-CE1 4.14Å; M105-Y110 HydrophobicContact CE-CE2 4.1Å; M105-Y110 HydrophobicContact CE-CG 3.63Å; M105-Y110 HydrophobicContact CG-CD2 3.9Å; M105-Y110 HydrophobicContact CG-CE2 3.93Å; M105-Y110 PolarHBondContact O-N 2.97Å; M105-M113 HydrophobicContact CE-CB 4.15Å; M105-M113 HydrophobicContact CE-CG 4.24Å; M105-M113 HydrophobicContact CE-SD 3.81Å; M105-M113 HydrophobicContact SD-SD 3.95Å; M105-F137 HydrophobicContact CB-CE1 3.53Å; M105-F137 HydrophobicContact CB-CZ 3.52Å; M105-F137 HydrophobicContact CE-CE2 3.89Å; M105-F137 HydrophobicContact CE-CZ 3.67Å; M105-F137 HydrophobicContact CG-CZ 4.31Å; M105-F137 HydrophobicContact SD-CE2 4.46Å; M105-F137 HydrophobicContact SD-CZ 3.84Å
106N98.9Very high97.7Very high26 Ų2622.9 Ų22.914%0.13911%0.11CC..Hα-helixtrans-62.1-42.1171.6-76.5-20.7000111.9A102 H103 F104 L108 R109 E134 K136 F137A102-N106 WeakPolarHBondContact O-CB 3.19Å; A102-N106 PolarHBondContact O-N 3.45Å; A102-N106 PolarHBondContact O-ND2 3.31Å; H103-N106 WeakPolarHBondContact O-CB 3.31Å; H103-N106 PolarHBondContact O-N 3.39Å; F104-N106 VanDerWaalsContact C-N 3.32Å; F104-N106 PolarHBondContact O-N 3.36Å; N106-L108 VanDerWaalsContact C-N 3.33Å; N106-L108 PolarHBondContact O-N 3.42Å; N106-R109 PolarHBondContact O-N 3.21Å; N106-E134 PolarHBondContact ND2-O 3.24Å; N106-K136 HydrophobicContact CB-CD 4.26Å; N106-K136 WeakPolarHBondContact OD1-CB 3.39Å; N106-K136 PolarHBondContact OD1-N 3.48Å; N106-F137 WeakPolarHBondContact OD1-CE1 3.37Å
107A98.6Very high97.1Very high33 Ų3321.4 Ų21.427%0.27310%0.104SC..Hα-helixtrans-63-39.4176.600000112F65 H103 F104 M105 R109 I320F65-A107 WeakPolarHBondContact CE2-O 3.47Å; H103-A107 PolarHBondContact O-N 2.83Å; F104-A107 WeakPolarHBondContact O-CB 3.17Å; F104-A107 PolarHBondContact O-N 3.29Å; M105-A107 VanDerWaalsContact C-N 3.35Å; A107-R109 PolarHBondContact O-N 3.42Å; A107-I320 HydrophobicContact CB-CD1 3.96Å
108L98.6Very high97Very high1 Ų117.2 Ų17.21%0.0059%0.086CC..Hα-helixtrans-74.2-12.2174.3-88.971.5000113.1V61 L64 F65 R72 L80 F104 M105 N106 Y110V61-L108 HydrophobicContact CG2-CD1 3.28Å; V61-L108 HydrophobicContact CG2-CD2 3.82Å; V61-L108 HydrophobicContact CG2-CG 4.22Å; L64-L108 HydrophobicContact CB-CD2 4.25Å; L64-L108 HydrophobicContact CD2-CD2 3.4Å; L64-L108 HydrophobicContact CG-CD2 3.55Å; F65-L108 HydrophobicContact CB-CD1 4.11Å; F65-L108 HydrophobicContact CB-CG 4.27Å; F65-L108 HydrophobicContact CD2-CD1 3.88Å; F65-L108 HydrophobicContact CD2-CG 4.01Å; R72-L108 PolarHBondContact NH1-O 3Å; L80-L108 HydrophobicContact CD2-CB 4.31Å; F104-L108 WeakPolarHBondContact O-CD1 3.48Å; F104-L108 PolarHBondContact O-N 3.15Å; M105-L108 CarbonylContact O-C 3.53Å; M105-L108 PolarHBondContact O-N 3.44Å; N106-L108 VanDerWaalsContact C-N 3.33Å; N106-L108 PolarHBondContact O-N 3.42Å; L108-Y110 HydrophobicContact CB-CD2 3.97Å; L108-Y110 HydrophobicContact CB-CE2 3.87Å; L108-Y110 HydrophobicContact CD2-CE2 3.96Å
109R98.8Very high97Very high140 Ų14017.2 Ų17.253%0.5289%0.086SC..THydrogen-bonded Turntrans55.756.2-177.3-56.3179.6-73.31711110.9R72 M105 N106 A107R72-R109 PolarHBondContact NH2-O 2.59Å; M105-R109 PolarHBondContact O-N 3.1Å; N106-R109 PolarHBondContact O-N 3.21Å; A107-R109 PolarHBondContact O-N 3.42Å
110Y98.9Very high96.6Very high12 Ų1216.3 Ų16.35%0.0478%0.078CC..  trans-54.9146.7168.6-84.2-98000110.3T34 L80 D82 M105 L108 F137T34-Y110 WeakPolarHBondContact OG1-CE1 3.48Å; T34-Y110 PolarHBondContact OG1-OH 3.09Å; L80-Y110 HydrophobicContact CD1-CD1 4.41Å; L80-Y110 HydrophobicContact CD1-CE1 3.91Å; L80-Y110 HydrophobicContact CD2-CD1 4.03Å; L80-Y110 HydrophobicContact CD2-CD2 3.92Å; L80-Y110 HydrophobicContact CD2-CE1 3.99Å; L80-Y110 HydrophobicContact CD2-CE2 3.92Å; L80-Y110 HydrophobicContact CD2-CG 3.98Å; L80-Y110 HydrophobicContact CG-CD1 3.62Å; L80-Y110 HydrophobicContact CG-CD2 4.43Å; L80-Y110 HydrophobicContact CG-CE1 3.6Å; L80-Y110 HydrophobicContact CG-CE2 4.46Å; L80-Y110 HydrophobicContact CG-CG 4.05Å; D82-Y110 HydrophobicContact CB-CD1 3.86Å; D82-Y110 HydrophobicContact CB-CE1 3.71Å; M105-Y110 HydrophobicContact CB-CD2 3.69Å; M105-Y110 HydrophobicContact CB-CE2 4.18Å; M105-Y110 HydrophobicContact CB-CG 4.43Å; M105-Y110 HydrophobicContact CE-CD1 3.8Å; M105-Y110 HydrophobicContact CE-CD2 3.8Å; M105-Y110 HydrophobicContact CE-CE1 4.14Å; M105-Y110 HydrophobicContact CE-CE2 4.1Å; M105-Y110 HydrophobicContact CE-CG 3.63Å; M105-Y110 HydrophobicContact CG-CD2 3.9Å; M105-Y110 HydrophobicContact CG-CE2 3.93Å; M105-Y110 PolarHBondContact O-N 2.97Å; L108-Y110 HydrophobicContact CB-CD2 3.97Å; L108-Y110 HydrophobicContact CB-CE2 3.87Å; L108-Y110 HydrophobicContact CD2-CE2 3.96Å; Y110-F137 WeakPolarHBondContact O-CB 3.49Å
111D98.9Very high95.7Very high47 Ų4717.6 Ų17.625%0.2519%0.085SC..SBendtrans-95.1-30.8-177.7-66.3-73.9000111.6R72 L79 L80 L81 P138 L164R72-D111 IonicContact NH2-OD2 2.69Å; R72-D111 PolarHBondContact NH2-OD2 3.25Å; L79-D111 HydrophobicContact CD2-CB 3.8Å; L80-D111 PolarHBondContact N-OD2 2.97Å; L80-D111 PolarHBondContact O-N 3.45Å; L81-D111 HydrophobicContact CD2-CB 4.36Å; D111-P138 WeakPolarHBondContact O-CD 3.46Å; D111-P138 VanDerWaalsContact O-CG 3.29Å; D111-P138 WeakPolarHBondContact O-CG 3.29Å; D111-L164 HydrophobicContact CB-CD1 4.11Å; D111-L164 WeakPolarHBondContact O-CD1 3.18Å
112A98.9Very high95.1Very high0 Ų020.2 Ų20.20%010%0.099CC..EExtended strand (participates in β ladder)trans-160.5158.1167.400000111.3L81 D82 P138 L140 I173 L218L81-A112 WeakPolarHBondContact CA-O 3.36Å; L81-A112 HydrophobicContact CD2-CB 4.03Å; D82-A112 PolarHBondContact N-O 3.06Å; A112-P138 WeakPolarHBondContact CA-O 3.49Å; A112-P138 HydrophobicContact CB-CG 3.86Å; A112-L140 HydrophobicContact CB-CD1 3.95Å; A112-I173 HydrophobicContact CB-CD1 4.08Å; A112-L218 HydrophobicContact CB-CD2 4.2Å
113M98.9Very high94.6Very high0 Ų020.6 Ų20.60%010%0.102CC..EExtended strand (participates in β ladder)trans-131.8136.3171.5175.2-178.7-178.700109.5D82 Q86 M105 E119 L131 F137 P138 I139 L140D82-M113 HydrophobicContact CB-CB 4.18Å; D82-M113 HydrophobicContact CB-CG 4.04Å; D82-M113 CarbonylContact O-C 3.59Å; D82-M113 VanDerWaalsContact O-CA 3.29Å; D82-M113 WeakPolarHBondContact O-CA 3.16Å; Q86-M113 HydrophobicContact CB-CE 4.08Å; Q86-M113 HydrophobicContact CG-CE 3.89Å; M105-M113 HydrophobicContact CE-CB 4.15Å; M105-M113 HydrophobicContact CE-CG 4.24Å; M105-M113 HydrophobicContact CE-SD 3.81Å; M105-M113 HydrophobicContact SD-SD 3.95Å; M113-E119 HydrophobicContact CE-CG 3.91Å; M113-L131 HydrophobicContact CE-CD2 4.36Å; M113-L131 HydrophobicContact SD-CD2 4.32Å; M113-F137 HydrophobicContact CB-CD2 4.11Å; M113-F137 HydrophobicContact CB-CE2 3.69Å; M113-F137 HydrophobicContact SD-CE2 4.37Å; M113-P138 PolarHBondContact N-O 3.33Å; M113-I139 CarbonylContact O-C 3.39Å; M113-I139 VanDerWaalsContact O-CA 3.31Å; M113-I139 WeakPolarHBondContact O-CA 3.3Å; M113-L140 PolarHBondContact O-N 3.24Å
114A98.9Very high94.3Very high0 Ų018.1 Ų18.10%09%0.092CC..EExtended strand (participates in β ladder)trans-89.3147.516300000110.8D82 G84 G116 L140 L218D82-A114 PolarHBondContact O-N 3.39Å; G84-A114 WeakPolarHBondContact CA-O 3.41Å; G84-A114 PolarHBondContact N-O 2.94Å; A114-G116 PolarHBondContact O-N 3.21Å; A114-L140 VanDerWaalsContact CA-O 3.31Å; A114-L140 WeakPolarHBondContact CA-O 3.48Å; A114-L218 HydrophobicContact CB-CD2 4.37Å; A114-L218 HydrophobicContact CB-CG 3.91Å; A114-L218 WeakPolarHBondContact CB-O 3.42Å
115L98.6Very high94Very high1 Ų124.3 Ų24.31%0.00512%0.121CC..  trans-72.3127.5173.6-68.5172.3000110.2E119 F120 L127 I139 L140 I144 Y158 T177L115-E119 HydrophobicContact CD2-CB 3.99Å; L115-E119 HydrophobicContact CD2-CG 4.04Å; L115-F120 HydrophobicContact CB-CE2 4.31Å; L115-F120 HydrophobicContact CD1-CZ 4.01Å; L115-L127 HydrophobicContact CD1-CD2 4.19Å; L115-L127 HydrophobicContact CD2-CD1 3.8Å; L115-L127 HydrophobicContact CD2-CD2 4.17Å; L115-I139 HydrophobicContact CD1-CG2 4.13Å; L115-I139 HydrophobicContact CD2-CG2 3.46Å; L115-I139 VanDerWaalsContact CD2-CG2 3.46Å; L115-I139 HydrophobicContact CG-CG2 3.55Å; L115-L140 PolarHBondContact N-O 3.39Å; L115-I144 HydrophobicContact CD1-CD1 4.24Å; L115-Y158 HydrophobicContact CD1-CG 4.43Å; L115-T177 WeakPolarHBondContact O-CB 3.23Å; L115-T177 WeakPolarHBondContact O-CG2 3.04Å; L115-T177 PolarHBondContact O-OG1 2.83Å
116G92.4Very high93.6Very high0 Ų024.7 Ų24.70%013%0.126CC..  trans-89.5-179.5164.300000112.2D85 A114 E119 F120 H220D85-G116 WeakPolarHBondContact OD1-CA 3.43Å; A114-G116 PolarHBondContact O-N 3.21Å; G116-E119 WeakPolarHBondContact CA-OE2 3.31Å; G116-E119 PolarHBondContact N-OE2 3.03Å; G116-F120 WeakPolarHBondContact O-CD2 3.05Å; G116-F120 WeakPolarHBondContact O-CE2 3.47Å; G116-H220 VanDerWaalsContact CA-CD2 3.49Å; G116-H220 WeakPolarHBondContact CA-CD2 3.43Å
117N81Confident93.3Very high2 Ų223.5 Ų23.51%0.01112%0.119CC..SBendtrans-74.2-32.5179.959.2-98.5000111.5D85 E119 F120 T181 L184 S185 H220 H243D85-N117 PolarHBondContact OD1-N 3.08Å; N117-E119 VanDerWaalsContact C-N 3.27Å; N117-E119 PolarHBondContact O-N 2.88Å; N117-F120 PolarHBondContact O-N 2.99Å; N117-T181 HydrophobicContact CB-CG2 3.9Å; N117-L184 HydrophobicContact CB-CB 4.42Å; N117-S185 WeakPolarHBondContact O-CB 3.47Å; N117-S185 PolarHBondContact O-OG 2.94Å; N117-S185 VanDerWaalsContact O-OG 3.07Å; N117-H220 PolarHBondContact OD1-NE2 2.94Å; N117-H243 PolarHBondContact OD1-CE1 2.86Å; N117-H243 PolarHBondContact OD1-ND1 3.12Å
118H90.6Very high93.2Very high10 Ų1022.3 Ų22.35%0.04611%0.108CC..G310 helixtrans-75.3-14.9-177.4-78.4-57000114.2H38 D85 Y87 Q88 F120 D121 R395 F417H38-H118 AromaticContact CE1-CD2 3.64Å; D85-H118 WeakPolarHBondContact OD1-CB 3.35Å; D85-H118 IonicContact OD1-CD2 2.75Å; D85-H118 PolarHBondContact OD1-N 2.72Å; D85-H118 IonicContact OD2-CD2 2.96Å; D85-H118 PolarHBondContact OD2-CD2 3.48Å; D85-H118 VanDerWaalsContact OD2-CD2 3.23Å; Y87-H118 VanDerWaalsContact CB-O 3.27Å; Y87-H118 WeakPolarHBondContact CB-O 3.34Å; Q88-H118 HydrophobicContact CB-CB 3.95Å; H118-F120 PolarHBondContact O-N 2.83Å; H118-F120 VanDerWaalsContact O-N 3.12Å; H118-D121 WeakPolarHBondContact CA-OD1 3.5Å; H118-D121 IonicContact CE1-OD1 3.49Å; H118-D121 IonicContact CE1-OD2 3.02Å; H118-D121 IonicContact CG-OD1 3.87Å; H118-D121 IonicContact CG-OD2 3.4Å; H118-D121 IonicContact ND1-OD1 2.99Å; H118-D121 PolarHBondContact ND1-OD1 2.89Å; H118-D121 IonicContact ND1-OD2 2.82Å; H118-D121 PolarHBondContact ND1-OD2 2.9Å; H118-D121 WeakPolarHBondContact O-CB 3.5Å; H118-D121 PolarHBondContact O-N 3.19Å; H118-D121 VanDerWaalsContact O-N 3.11Å; H118-R395 PolarHBondContact CE1-NH2 3.29Å; H118-R395 PolarHBondContact NE2-NH2 3.3Å; H118-F417 AromaticContact CE1-CE1 3.7Å
119E95Very high93.1Very high0 Ų027.8 Ų27.80%013%0.134CC..G310 helixtrans-59.6-19.6168.5-84.470.5-125.900112.8D85 Q86 Y87 M113 L115 G116 N117 L127 L131D85-E119 WeakPolarHBondContact CA-OE1 3.35Å; D85-E119 PolarHBondContact N-OE1 3.13Å; D85-E119 PolarHBondContact N-OE2 3.33Å; Q86-E119 PolarHBondContact N-OE1 2.85Å; Y87-E119 WeakPolarHBondContact CB-OE1 3.19Å; Y87-E119 HydrophobicContact CD1-CG 4.32Å; Y87-E119 HydrophobicContact CD2-CB 4.47Å; Y87-E119 HydrophobicContact CD2-CG 4.47Å; Y87-E119 HydrophobicContact CG-CG 4.18Å; Y87-E119 PolarHBondContact N-OE1 2.82Å; M113-E119 HydrophobicContact CE-CG 3.91Å; L115-E119 HydrophobicContact CD2-CB 3.99Å; L115-E119 HydrophobicContact CD2-CG 4.04Å; G116-E119 WeakPolarHBondContact CA-OE2 3.31Å; G116-E119 PolarHBondContact N-OE2 3.03Å; N117-E119 VanDerWaalsContact C-N 3.27Å; N117-E119 PolarHBondContact O-N 2.88Å; E119-L127 HydrophobicContact CB-CD1 3.99Å; E119-L127 HydrophobicContact CG-CD1 4.42Å; E119-L131 HydrophobicContact CG-CD2 3.97Å
120F89.9Confident92.9Very high2 Ų221.8 Ų21.81%0.00911%0.113CC..G310 helixtrans-96.65.5178.2-60.7-85.2000114.5L115 G116 N117 H118 N122 G123 L127 I144 T177 T181 S185 N186 P187 L191 F193L115-F120 HydrophobicContact CB-CE2 4.31Å; L115-F120 HydrophobicContact CD1-CZ 4.01Å; G116-F120 WeakPolarHBondContact O-CD2 3.05Å; G116-F120 WeakPolarHBondContact O-CE2 3.47Å; N117-F120 PolarHBondContact O-N 2.99Å; H118-F120 PolarHBondContact O-N 2.83Å; H118-F120 VanDerWaalsContact O-N 3.12Å; F120-N122 VanDerWaalsContact C-N 3.32Å; F120-N122 PolarHBondContact O-N 3.44Å; F120-G123 PolarHBondContact O-N 3.31Å; F120-L127 HydrophobicContact CD1-CD2 3.86Å; F120-L127 HydrophobicContact CE1-CD2 3.36Å; F120-L127 HydrophobicContact CE2-CD2 4.45Å; F120-L127 HydrophobicContact CZ-CD2 3.7Å; F120-I144 HydrophobicContact CE2-CD1 4.14Å; F120-I144 HydrophobicContact CZ-CD1 3.66Å; F120-T177 HydrophobicContact CE2-CG2 4.45Å; F120-T181 HydrophobicContact CB-CG2 4.47Å; F120-T181 HydrophobicContact CD2-CG2 3.73Å; F120-T181 HydrophobicContact CE2-CG2 4.32Å; F120-T181 HydrophobicContact CG-CG2 4.25Å; F120-S185 PolarHBondContact O-OG 3.17Å; F120-N186 CarbonylContact O-C 3.59Å; F120-N186 PolarHBondContact O-N 3.04Å; F120-P187 HydrophobicContact CB-CB 4.21Å; F120-P187 HydrophobicContact CD1-CB 3.88Å; F120-P187 HydrophobicContact CG-CB 4.08Å; F120-L191 HydrophobicContact CD1-CD1 4.03Å; F120-L191 HydrophobicContact CE1-CD1 3.48Å; F120-L191 VanDerWaalsContact CE1-CD1 3.48Å; F120-L191 HydrophobicContact CZ-CD1 4.38Å; F120-F193 HydrophobicContact CD2-CZ 4.39Å; F120-F193 HydrophobicContact CE1-CZ 4.35Å; F120-F193 HydrophobicContact CE2-CE1 4.14Å; F120-F193 HydrophobicContact CE2-CZ 4.04Å; F120-F193 HydrophobicContact CZ-CE1 4.35Å; F120-F193 HydrophobicContact CZ-CZ 4.03Å
121D80.4Confident92.8Very high28 Ų2821.2 Ų21.215%0.1511%0.111CC..THydrogen-bonded Turntrans-62.8-38.4-173.2-84.812.2000112.7Q88 F93 H118 G123 S185Q88-D121 WeakPolarHBondContact CB-OD2 3.42Å; Q88-D121 VanDerWaalsContact CG-OD2 3.26Å; Q88-D121 WeakPolarHBondContact CG-OD2 3.45Å; Q88-D121 PolarHBondContact NE2-OD2 2.78Å; F93-D121 HydrophobicContact CE1-CB 4.37Å; F93-D121 HydrophobicContact CZ-CB 4.49Å; H118-D121 WeakPolarHBondContact CA-OD1 3.5Å; H118-D121 IonicContact CE1-OD1 3.49Å; H118-D121 IonicContact CE1-OD2 3.02Å; H118-D121 IonicContact CG-OD1 3.87Å; H118-D121 IonicContact CG-OD2 3.4Å; H118-D121 IonicContact ND1-OD1 2.99Å; H118-D121 PolarHBondContact ND1-OD1 2.89Å; H118-D121 IonicContact ND1-OD2 2.82Å; H118-D121 PolarHBondContact ND1-OD2 2.9Å; H118-D121 WeakPolarHBondContact O-CB 3.5Å; H118-D121 PolarHBondContact O-N 3.19Å; H118-D121 VanDerWaalsContact O-N 3.11Å; D121-G123 PolarHBondContact O-N 3.33Å; D121-S185 VanDerWaalsContact CA-OG 3.25Å; D121-S185 WeakPolarHBondContact CA-OG 3.29Å; D121-S185 PolarHBondContact N-OG 2.74Å; D121-S185 WeakPolarHBondContact OD1-CB 3.29Å; D121-S185 PolarHBondContact OD1-OG 2.86Å
122N85.7Confident92.8Very high56 Ų5619.6 Ų19.630%0.29910%0.102SC..THydrogen-bonded Turntrans-89.420.1176-68.4-35.8000112.5F93 F120 G126F93-N122 WeakPolarHBondContact CZ-ND2 3.48Å; F120-N122 VanDerWaalsContact C-N 3.32Å; F120-N122 PolarHBondContact O-N 3.44Å; N122-G126 PolarHBondContact O-N 2.77Å
123G86.9Confident92.7Very high7 Ų725.5 Ų25.57%0.07213%0.128CC..Hα-helixtrans75.1178.3-173.700000113.3F120 D121 E125 G126 L127 N186F120-G123 PolarHBondContact O-N 3.31Å; D121-G123 PolarHBondContact O-N 3.33Å; G123-E125 VanDerWaalsContact C-N 3.27Å; G123-E125 PolarHBondContact O-N 2.91Å; G123-G126 PolarHBondContact O-N 3.03Å; G123-L127 PolarHBondContact O-N 2.87Å; G123-N186 WeakPolarHBondContact CA-O 3.5Å
124V92.2Very high92.7Very high9 Ų930.2 Ų30.26%0.05515%0.15CC..Hα-helixtrans-68.2-30.8-180-1750000111.3L127 I128 L150 I154 P187 L191V124-L127 WeakPolarHBondContact O-CB 3.47Å; V124-L127 PolarHBondContact O-N 3.3Å; V124-I128 HydrophobicContact CG1-CD1 4.02Å; V124-I128 HydrophobicContact CG1-CG1 4.34Å; V124-I128 WeakPolarHBondContact O-CG1 3.41Å; V124-I128 PolarHBondContact O-N 3.07Å; V124-L150 HydrophobicContact CG1-CD1 3.83Å; V124-L150 HydrophobicContact CG1-CD2 4.25Å; V124-L150 HydrophobicContact CG2-CD2 4.32Å; V124-I154 HydrophobicContact CG1-CD1 3.87Å; V124-P187 VanDerWaalsContact CG2-O 3.32Å; V124-P187 WeakPolarHBondContact CG2-O 3.41Å; V124-L191 HydrophobicContact CG2-CD1 3.6Å; V124-L191 HydrophobicContact CG2-CG 4.17Å
125E93.4Very high92.6Very high132 Ų13231.2 Ų31.262%0.61716%0.158SC*.Hα-helixtrans-62-46174.3-64.577.4-168.600111.5G123 L127 I128 E129G123-E125 VanDerWaalsContact C-N 3.27Å; G123-E125 PolarHBondContact O-N 2.91Å; E125-L127 PolarHBondContact O-N 2.79Å; E125-I128 PolarHBondContact O-N 3.4Å; E125-E129 PolarHBondContact O-N 2.8Å
126G89.9Confident92.7Very high13 Ų1339.9 Ų39.913%0.13420%0.195CC..Hα-helixtrans-72.1-14.5177.300000114.6Y87 N122 G123 E129Y87-G126 PolarHBondContact OH-O 2.84Å; Y87-G126 VanDerWaalsContact OH-O 3.11Å; N122-G126 PolarHBondContact O-N 2.77Å; G123-G126 PolarHBondContact O-N 3.03Å; G126-E129 CarbonylContact C-O 3.54Å; G126-E129 WeakPolarHBondContact CA-O 3.37Å
127L92.9Very high93Very high0 Ų040.6 Ų40.60%020%0.199CC..Iπ-helixtrans-80.7-49167.5176.553.8000110.9L115 E119 F120 G123 V124 E125 E129 L131 L132L115-L127 HydrophobicContact CD1-CD2 4.19Å; L115-L127 HydrophobicContact CD2-CD1 3.8Å; L115-L127 HydrophobicContact CD2-CD2 4.17Å; E119-L127 HydrophobicContact CB-CD1 3.99Å; E119-L127 HydrophobicContact CG-CD1 4.42Å; F120-L127 HydrophobicContact CD1-CD2 3.86Å; F120-L127 HydrophobicContact CE1-CD2 3.36Å; F120-L127 HydrophobicContact CE2-CD2 4.45Å; F120-L127 HydrophobicContact CZ-CD2 3.7Å; G123-L127 PolarHBondContact O-N 2.87Å; V124-L127 WeakPolarHBondContact O-CB 3.47Å; V124-L127 PolarHBondContact O-N 3.3Å; E125-L127 PolarHBondContact O-N 2.79Å; L127-E129 PolarHBondContact O-N 2.8Å; L127-L131 HydrophobicContact CD1-CB 4.49Å; L127-L131 HydrophobicContact CD1-CD2 3.94Å; L127-L131 PolarHBondContact O-N 3.36Å; L127-L132 HydrophobicContact CD1-CD2 3.97Å; L127-L132 HydrophobicContact CD1-CG 4.06Å; L127-L132 HydrophobicContact CD2-CD1 4.42Å; L127-L132 HydrophobicContact CG-CD1 3.98Å; L127-L132 HydrophobicContact CG-CD2 4.2Å; L127-L132 HydrophobicContact CG-CG 3.91Å; L127-L132 WeakPolarHBondContact O-CG 3.28Å; L127-L132 PolarHBondContact O-N 2.77Å; L127-L132 VanDerWaalsContact O-N 3.09Å
128I96.6Very high93.8Very high8 Ų841.6 Ų41.64%0.04121%0.205CC..Iπ-helixtrans-59.5-49.6179.8-71169.3000110.5V124 E125 L132 K133 Q153 I154 L157V124-I128 HydrophobicContact CG1-CD1 4.02Å; V124-I128 HydrophobicContact CG1-CG1 4.34Å; V124-I128 WeakPolarHBondContact O-CG1 3.41Å; V124-I128 PolarHBondContact O-N 3.07Å; E125-I128 PolarHBondContact O-N 3.4Å; I128-L132 HydrophobicContact CG1-CD1 4.07Å; I128-L132 PolarHBondContact O-N 2.88Å; I128-K133 HydrophobicContact CG2-CD 4.42Å; I128-K133 HydrophobicContact CG2-CG 4.33Å; I128-K133 WeakPolarHBondContact O-CG 3.26Å; I128-K133 PolarHBondContact O-N 3.03Å; I128-Q153 HydrophobicContact CD1-CG 4.08Å; I128-I154 HydrophobicContact CD1-CG1 4.44Å; I128-I154 HydrophobicContact CG1-CD1 4.41Å; I128-I154 HydrophobicContact CG1-CG1 4.35Å; I128-L157 HydrophobicContact CG1-CD1 4.16Å; I128-L157 HydrophobicContact CG2-CD1 4.02Å
129E95.8Very high94.2Very high117 Ų11741.4 Ų41.455%0.54720%0.204SC..Iπ-helixtrans-117.8117.2174.3-80-177.8-164.500109.8E125 G126 L127 K133E125-E129 PolarHBondContact O-N 2.8Å; G126-E129 CarbonylContact C-O 3.54Å; G126-E129 WeakPolarHBondContact CA-O 3.37Å; L127-E129 PolarHBondContact O-N 2.8Å; E129-K133 HydrophobicContact CG-CD 3.7Å; E129-K133 HydrophobicContact CG-CG 4.43Å; E129-K133 WeakPolarHBondContact OE1-CE 3.39Å; E129-K133 IonicContact OE1-NZ 2.69Å; E129-K133 PolarHBondContact OE1-NZ 2.92Å
130P95.1Very high94.4Very high13 Ų1341.4 Ų41.48%0.08420%0.204CC..Iπ-helixcis-95.7-27.212.831.9-30.8000115.6K97 A99 L132 K133 E134K97-P130 WeakPolarHBondContact O-CD 3.31Å; A99-P130 VanDerWaalsContact CA-CG 3.49Å; A99-P130 HydrophobicContact CB-CB 4.23Å; A99-P130 HydrophobicContact CB-CG 3.9Å; P130-L132 PolarHBondContact O-N 3.37Å; P130-K133 PolarHBondContact O-N 2.78Å; P130-E134 HydrophobicContact CB-CG 4.33Å; P130-E134 WeakPolarHBondContact CB-OE1 3.38Å; P130-E134 WeakPolarHBondContact O-CB 3.45Å; P130-E134 WeakPolarHBondContact O-CG 3.33Å; P130-E134 PolarHBondContact O-N 2.75Å
131L97.8Very high94.8Very high0 Ų041.3 Ų41.30%020%0.204CC..Iπ-helixtrans-59.8-54.1-159178.264.8000114.4Y87 V101 A102 M113 E119 L127 K133 E134 A135 I139Y87-L131 HydrophobicContact CD1-CD2 4.49Å; Y87-L131 HydrophobicContact CE1-CB 4.05Å; Y87-L131 HydrophobicContact CE1-CD2 3.82Å; Y87-L131 HydrophobicContact CE1-CG 4.4Å; Y87-L131 WeakPolarHBondContact OH-CB 3.44Å; V101-L131 HydrophobicContact CG1-CD1 4.12Å; A102-L131 HydrophobicContact CB-CD1 4.32Å; M113-L131 HydrophobicContact CE-CD2 4.36Å; M113-L131 HydrophobicContact SD-CD2 4.32Å; E119-L131 HydrophobicContact CG-CD2 3.97Å; L127-L131 HydrophobicContact CD1-CB 4.49Å; L127-L131 HydrophobicContact CD1-CD2 3.94Å; L127-L131 PolarHBondContact O-N 3.36Å; L131-K133 PolarHBondContact O-N 3.08Å; L131-E134 PolarHBondContact O-N 3.24Å; L131-A135 HydrophobicContact CD1-CB 4.39Å; L131-A135 VanDerWaalsContact O-CB 3.27Å; L131-A135 WeakPolarHBondContact O-CB 3.31Å; L131-A135 PolarHBondContact O-N 2.96Å; L131-I139 HydrophobicContact CD1-CD1 4.11Å; L131-I139 HydrophobicContact CD2-CD1 4.22Å; L131-I139 HydrophobicContact CG-CD1 3.7Å
132L97.7Very high95.7Very high14 Ų1440 Ų407%0.07320%0.198CC..Iπ-helixtrans-66.7-24.9-175.2-57-173.6000113.5L127 I128 P130 I139 I154 L157L127-L132 HydrophobicContact CD1-CD2 3.97Å; L127-L132 HydrophobicContact CD1-CG 4.06Å; L127-L132 HydrophobicContact CD2-CD1 4.42Å; L127-L132 HydrophobicContact CG-CD1 3.98Å; L127-L132 HydrophobicContact CG-CD2 4.2Å; L127-L132 HydrophobicContact CG-CG 3.91Å; L127-L132 WeakPolarHBondContact O-CG 3.28Å; L127-L132 PolarHBondContact O-N 2.77Å; L127-L132 VanDerWaalsContact O-N 3.09Å; I128-L132 HydrophobicContact CG1-CD1 4.07Å; I128-L132 PolarHBondContact O-N 2.88Å; P130-L132 PolarHBondContact O-N 3.37Å; L132-I139 HydrophobicContact CD2-CB 4.07Å; L132-I139 HydrophobicContact CD2-CD1 3.49Å; L132-I139 VanDerWaalsContact CD2-CD1 3.49Å; L132-I139 HydrophobicContact CD2-CG1 4.37Å; L132-I139 HydrophobicContact CD2-CG2 3.73Å; L132-I154 HydrophobicContact CD1-CD1 4.01Å; L132-I154 HydrophobicContact CD1-CG1 3.97Å; L132-L157 HydrophobicContact CB-CB 4.06Å; L132-L157 HydrophobicContact CB-CD1 4.47Å; L132-L157 HydrophobicContact CD1-CB 3.81Å; L132-L157 HydrophobicContact CD1-CD1 4.39Å
133K97.3Very high96.3Very high123 Ų12337.4 Ų37.454%0.53518%0.183SC..Hα-helixtrans-88.5-29178.5-73.9-168.9-175176.40113.6I128 E129 P130 L131I128-K133 HydrophobicContact CG2-CD 4.42Å; I128-K133 HydrophobicContact CG2-CG 4.33Å; I128-K133 WeakPolarHBondContact O-CG 3.26Å; I128-K133 PolarHBondContact O-N 3.03Å; E129-K133 HydrophobicContact CG-CD 3.7Å; E129-K133 HydrophobicContact CG-CG 4.43Å; E129-K133 WeakPolarHBondContact OE1-CE 3.39Å; E129-K133 IonicContact OE1-NZ 2.69Å; E129-K133 PolarHBondContact OE1-NZ 2.92Å; P130-K133 PolarHBondContact O-N 2.78Å; L131-K133 PolarHBondContact O-N 3.08Å
134E98.3Very high96.8Very high99 Ų9937.2 Ų37.246%0.46318%0.181SC..Hα-helixtrans-101.1-20.6-173-66.2-173.4-158.100114.1A102 N106 P130 L131 K136A102-E134 HydrophobicContact CB-CB 3.8Å; N106-E134 PolarHBondContact ND2-O 3.24Å; P130-E134 HydrophobicContact CB-CG 4.33Å; P130-E134 WeakPolarHBondContact CB-OE1 3.38Å; P130-E134 WeakPolarHBondContact O-CB 3.45Å; P130-E134 WeakPolarHBondContact O-CG 3.33Å; P130-E134 PolarHBondContact O-N 2.75Å; L131-E134 PolarHBondContact O-N 3.24Å; E134-K136 PolarHBondContact O-N 3.03Å
135A98.3Very high97Very high21 Ų2140.5 Ų40.517%0.17419%0.194CC..  trans-62.2133.2176.800000111.6L131 F137 I139L131-A135 HydrophobicContact CD1-CB 4.39Å; L131-A135 VanDerWaalsContact O-CB 3.27Å; L131-A135 WeakPolarHBondContact O-CB 3.31Å; L131-A135 PolarHBondContact O-N 2.96Å; A135-F137 VanDerWaalsContact C-N 3.31Å; A135-F137 HydrophobicContact CB-CD2 4.4Å; A135-F137 HydrophobicContact CB-CE1 4.22Å; A135-F137 HydrophobicContact CB-CE2 4.06Å; A135-F137 HydrophobicContact CB-CZ 3.96Å; A135-I139 HydrophobicContact CB-CD1 3.8Å; A135-I139 HydrophobicContact CB-CG1 4.37Å
136K98.7Very high97.1Very high183 Ų18335.4 Ų35.480%0.79618%0.175SC*.SBendtrans-95.413.2178-64.1176.4-176.41760112.7N106 E134N106-K136 HydrophobicContact CB-CD 4.26Å; N106-K136 WeakPolarHBondContact OD1-CB 3.39Å; N106-K136 PolarHBondContact OD1-N 3.48Å; E134-K136 PolarHBondContact O-N 3.03Å
137F98.8Very high97.1Very high16 Ų1640.4 Ų40.47%0.0719%0.193CC..SBendtrans-134.6154-178.650.3-95.2000109.5M105 N106 Y110 M113 A135 I139M105-F137 HydrophobicContact CB-CE1 3.53Å; M105-F137 HydrophobicContact CB-CZ 3.52Å; M105-F137 HydrophobicContact CE-CE2 3.89Å; M105-F137 HydrophobicContact CE-CZ 3.67Å; M105-F137 HydrophobicContact CG-CZ 4.31Å; M105-F137 HydrophobicContact SD-CE2 4.46Å; M105-F137 HydrophobicContact SD-CZ 3.84Å; N106-F137 WeakPolarHBondContact OD1-CE1 3.37Å; Y110-F137 WeakPolarHBondContact O-CB 3.49Å; M113-F137 HydrophobicContact CB-CD2 4.11Å; M113-F137 HydrophobicContact CB-CE2 3.69Å; M113-F137 HydrophobicContact SD-CE2 4.37Å; A135-F137 VanDerWaalsContact C-N 3.31Å; A135-F137 HydrophobicContact CB-CD2 4.4Å; A135-F137 HydrophobicContact CB-CE1 4.22Å; A135-F137 HydrophobicContact CB-CE2 4.06Å; A135-F137 HydrophobicContact CB-CZ 3.96Å; F137-I139 HydrophobicContact CE2-CG1 4.35Å; F137-I139 PolarHBondContact O-N 3.1Å
138P98.8Very high97.2Very high23 Ų2343 Ų4315%0.14922%0.219CC..  trans-62.9134.2178.529.2-39.5000111.7D111 A112 M113 L140 K162D111-P138 WeakPolarHBondContact O-CD 3.46Å; D111-P138 VanDerWaalsContact O-CG 3.29Å; D111-P138 WeakPolarHBondContact O-CG 3.29Å; A112-P138 WeakPolarHBondContact CA-O 3.49Å; A112-P138 HydrophobicContact CB-CG 3.86Å; M113-P138 PolarHBondContact N-O 3.33Å; P138-L140 HydrophobicContact CB-CD2 4.03Å; P138-K162 HydrophobicContact CB-CB 4.01Å; P138-K162 HydrophobicContact CB-CD 4.22Å; P138-K162 HydrophobicContact CB-CG 4Å; P138-K162 HydrophobicContact CG-CB 4.08Å; P138-K162 HydrophobicContact CG-CG 3.94Å
139I98.9Very high97Very high5 Ų547.7 Ų47.73%0.02625%0.251CS..EExtended strand (participates in β ladder)trans-103.1131.1169.6-65.8174.7000108.4M113 L115 L131 L132 A135 F137 Y158 L159M113-I139 CarbonylContact O-C 3.39Å; M113-I139 VanDerWaalsContact O-CA 3.31Å; M113-I139 WeakPolarHBondContact O-CA 3.3Å; L115-I139 HydrophobicContact CD1-CG2 4.13Å; L115-I139 HydrophobicContact CD2-CG2 3.46Å; L115-I139 VanDerWaalsContact CD2-CG2 3.46Å; L115-I139 HydrophobicContact CG-CG2 3.55Å; L131-I139 HydrophobicContact CD1-CD1 4.11Å; L131-I139 HydrophobicContact CD2-CD1 4.22Å; L131-I139 HydrophobicContact CG-CD1 3.7Å; L132-I139 HydrophobicContact CD2-CB 4.07Å; L132-I139 HydrophobicContact CD2-CD1 3.49Å; L132-I139 VanDerWaalsContact CD2-CD1 3.49Å; L132-I139 HydrophobicContact CD2-CG1 4.37Å; L132-I139 HydrophobicContact CD2-CG2 3.73Å; A135-I139 HydrophobicContact CB-CD1 3.8Å; A135-I139 HydrophobicContact CB-CG1 4.37Å; F137-I139 HydrophobicContact CE2-CG1 4.35Å; F137-I139 PolarHBondContact O-N 3.1Å; I139-Y158 CarbonylContact O-C 3.47Å; I139-Y158 VanDerWaalsContact O-CA 3.25Å; I139-Y158 WeakPolarHBondContact O-CA 3.18Å; I139-Y158 WeakPolarHBondContact O-CB 3.5Å; I139-L159 PolarHBondContact O-N 2.69Å
140L98.9Very high96.7Very high0 Ų042.9 Ų42.90%023%0.228CC..EExtended strand (participates in β ladder)trans-123.3135.4-162.8-54.8-179.7000113A112 M113 A114 L115 P138 L159 K162 I173A112-L140 HydrophobicContact CB-CD1 3.95Å; M113-L140 PolarHBondContact O-N 3.24Å; A114-L140 VanDerWaalsContact CA-O 3.31Å; A114-L140 WeakPolarHBondContact CA-O 3.48Å; L115-L140 PolarHBondContact N-O 3.39Å; P138-L140 HydrophobicContact CB-CD2 4.03Å; L140-L159 CarbonylContact C-O 3.55Å; L140-L159 WeakPolarHBondContact CA-O 3.36Å; L140-L159 HydrophobicContact CD2-CB 3.99Å; L140-K162 HydrophobicContact CD2-CB 4.08Å; L140-I173 HydrophobicContact CD1-CB 3.95Å; L140-I173 HydrophobicContact CD1-CG2 3.53Å
141S98.6Very high96.6Very high1 Ų144 Ų441%0.00724%0.239CC..  trans-167.1118162.4-168.20000110N143 I144 Y158 L159 T177S141-N143 PolarHBondContact OG-OD1 2.58Å; S141-I144 WeakPolarHBondContact OG-CD1 3.26Å; S141-I144 VanDerWaalsContact OG-CG1 3.3Å; S141-I144 WeakPolarHBondContact OG-CG1 3.26Å; S141-Y158 WeakPolarHBondContact O-CE2 3.01Å; S141-L159 PolarHBondContact N-O 3.38Å; S141-T177 WeakPolarHBondContact CB-OG1 3.21Å; S141-T177 PolarHBondContact OG-OG1 3.03Å
142A98.8Very high96.3Very high1 Ų148.7 Ų48.71%0.00827%0.271CS..SBendtrans-84.5-31-178.300000113.2K145 P160 V174 G175 L200 E203A142-K145 PolarHBondContact O-NZ 3.45Å; A142-P160 HydrophobicContact CB-CB 3.86Å; A142-V174 HydrophobicContact CB-CG2 4.13Å; A142-G175 WeakPolarHBondContact CB-O 3.27Å; A142-G175 PolarHBondContact N-O 3.2Å; A142-L200 HydrophobicContact CB-CD2 4.27Å; A142-E203 HydrophobicContact CB-CG 4.14Å
143N98.4Very high96.1Very high0 Ų053.1 Ų53.10%029%0.292CS..SBendtrans-92.33.3-173.275.3-51.5000113.9S141 Y176 T177 E194 A199S141-N143 PolarHBondContact OG-OD1 2.58Å; N143-Y176 WeakPolarHBondContact OD1-CA 3.48Å; N143-T177 PolarHBondContact ND2-O 2.93Å; N143-T177 PolarHBondContact OD1-N 3.03Å; N143-T177 PolarHBondContact OD1-O 2.63Å; N143-E194 HydrophobicContact CB-CB 4.3Å; N143-E194 PolarHBondContact ND2-O 3.01Å; N143-E194 PolarHBondContact O-N 2.86Å; N143-A199 HydrophobicContact CB-CB 3.39Å
144I97.7Very high95.9Very high4 Ų447.4 Ų47.42%0.02127%0.267CS..EExtended strand (participates in β ladder)trans-92.2124.9169.9-60.7175.2000109L115 F120 S141 Y158 T177 L191 V192 F193L115-I144 HydrophobicContact CD1-CD1 4.24Å; F120-I144 HydrophobicContact CE2-CD1 4.14Å; F120-I144 HydrophobicContact CZ-CD1 3.66Å; S141-I144 WeakPolarHBondContact OG-CD1 3.26Å; S141-I144 VanDerWaalsContact OG-CG1 3.3Å; S141-I144 WeakPolarHBondContact OG-CG1 3.26Å; I144-Y158 HydrophobicContact CB-CE2 4.16Å; I144-Y158 HydrophobicContact CG2-CE2 4.48Å; I144-Y158 PolarHBondContact O-OH 3.33Å; I144-Y158 VanDerWaalsContact O-OH 3.06Å; I144-T177 HydrophobicContact CD1-CG2 4.29Å; I144-L191 HydrophobicContact CG2-CB 4.41Å; I144-L191 HydrophobicContact CG2-CD1 4.38Å; I144-L191 HydrophobicContact CG2-CD2 4.07Å; I144-V192 CarbonylContact C-O 3.52Å; I144-V192 WeakPolarHBondContact CA-O 3.24Å; I144-F193 HydrophobicContact CD1-CD1 4.11Å; I144-F193 HydrophobicContact CD1-CE1 3.48Å; I144-F193 VanDerWaalsContact CD1-CE1 3.48Å; I144-F193 HydrophobicContact CD1-CZ 4.02Å; I144-F193 HydrophobicContact CG1-CD1 3.72Å; I144-F193 HydrophobicContact CG1-CE1 3.6Å; I144-F193 HydrophobicContact CG1-CG 4.44Å; I144-F193 HydrophobicContact CG1-CZ 4.22Å
145K96Very high95.7Very high77 Ų7747.1 Ų47.134%0.33528%0.276SS..EExtended strand (participates in β ladder)trans-118121.7172.4-56.9-57.1-178.6-150.70110.1A142 V192 E194A142-K145 PolarHBondContact O-NZ 3.45Å; K145-V192 PolarHBondContact N-O 3.13Å; K145-V192 PolarHBondContact O-N 2.83Å; K145-E194 WeakPolarHBondContact CE-OE2 3.36Å; K145-E194 HydrophobicContact CG-CG 4.2Å; K145-E194 WeakPolarHBondContact CG-OE1 3.46Å
146A95.1Very high95.4Very high25 Ų2548.8 Ų48.821%0.20730%0.295CS..EExtended strand (participates in β ladder)trans-83.7141.7173.500000111.4A151 I154 L191A146-A151 HydrophobicContact CB-CB 4.14Å; A146-I154 HydrophobicContact CB-CG2 3.67Å; A146-L191 HydrophobicContact CB-CD2 3.75Å
147K91.4Very high95.4Very high119 Ų11942.7 Ų42.752%0.51727%0.271SS..  trans-119.1159.8179.1-67.7-179.7173.5175.10111.5N190 V192K147-N190 PolarHBondContact N-O 2.83Å; K147-V192 HydrophobicContact CD-CG2 3.84Å; K147-V192 HydrophobicContact CG-CG2 4.49Å; K147-V192 VanDerWaalsContact NZ-CG2 3.31Å
148G93.9Very high95.3Very high54 Ų5443.3 Ų43.356%0.55727%0.273SS*.THydrogen-bonded Turntrans61.2-151.7174.700000113.1L150 A151G148-L150 PolarHBondContact O-N 3.46Å; G148-A151 WeakPolarHBondContact O-CB 3.14Å; G148-A151 PolarHBondContact O-N 2.72Å; G148-A151 VanDerWaalsContact O-N 3.11Å
149P92.1Very high95.3Very high107 Ų10744.8 Ų44.870%0.69528%0.28SS*.Hα-helixtrans-59.2-27.3179.7-2535000114.2A151 S152 Q153P149-A151 PolarHBondContact O-N 2.9Å; P149-S152 PolarHBondContact O-N 2.7Å; P149-S152 PolarHBondContact O-OG 3.08Å; P149-Q153 PolarHBondContact O-N 3.08Å
150L90.9Very high95.3Very high15 Ų1546.4 Ų46.48%0.07929%0.29CS..Hα-helixtrans-62.4-31.5178.1-177.562.6000111.9V124 G148 S152 Q153 I154 N190 L191V124-L150 HydrophobicContact CG1-CD1 3.83Å; V124-L150 HydrophobicContact CG1-CD2 4.25Å; V124-L150 HydrophobicContact CG2-CD2 4.32Å; G148-L150 PolarHBondContact O-N 3.46Å; L150-S152 VanDerWaalsContact C-N 3.33Å; L150-S152 PolarHBondContact O-N 3.41Å; L150-Q153 HydrophobicContact CD1-CB 4.44Å; L150-Q153 PolarHBondContact O-N 3.39Å; L150-Q153 VanDerWaalsContact O-N 3.08Å; L150-I154 WeakPolarHBondContact O-CG2 3.14Å; L150-I154 PolarHBondContact O-N 2.9Å; L150-N190 HydrophobicContact CB-CB 4.14Å; L150-N190 HydrophobicContact CD2-CB 3.67Å; L150-L191 HydrophobicContact CD2-CD2 3.64Å; L150-L191 HydrophobicContact CD2-CG 3.93Å
151A92.3Very high95.3Very high37 Ų3748.2 Ų48.231%0.30630%0.297SS..Hα-helixtrans-57.3-45.6179.300000112.2A146 G148 P149 S155A146-A151 HydrophobicContact CB-CB 4.14Å; G148-A151 WeakPolarHBondContact O-CB 3.14Å; G148-A151 PolarHBondContact O-N 2.72Å; G148-A151 VanDerWaalsContact O-N 3.11Å; P149-A151 PolarHBondContact O-N 2.9Å; A151-S155 VanDerWaalsContact O-CB 3.27Å; A151-S155 WeakPolarHBondContact O-CB 3.36Å; A151-S155 PolarHBondContact O-N 3.29Å; A151-S155 VanDerWaalsContact O-N 3.16Å
152S92.6Very high95.3Very high98 Ų9852.2 Ų52.269%0.68532%0.315SS*.Hα-helixtrans-68.2-34.1175.339.20000113.2P149 L150P149-S152 PolarHBondContact O-N 2.7Å; P149-S152 PolarHBondContact O-OG 3.08Å; L150-S152 VanDerWaalsContact C-N 3.33Å; L150-S152 PolarHBondContact O-N 3.41Å
153Q93.2Very high95.3Very high108 Ų10854.6 Ų54.651%0.50533%0.329SS..Hα-helixtrans-70.9-38.5-176.8-176.7-176.5-1.600112.5I128 P149 L150I128-Q153 HydrophobicContact CD1-CG 4.08Å; P149-Q153 PolarHBondContact O-N 3.08Å; L150-Q153 HydrophobicContact CD1-CB 4.44Å; L150-Q153 PolarHBondContact O-N 3.39Å; L150-Q153 VanDerWaalsContact O-N 3.08Å
154I93Very high95.4Very high3 Ų355.6 Ų55.62%0.01533%0.334CS..Hα-helixtrans-98.6-5.2-176-153.5169.6000113.4V124 I128 L132 A146 L150 G156 L157 Y158V124-I154 HydrophobicContact CG1-CD1 3.87Å; I128-I154 HydrophobicContact CD1-CG1 4.44Å; I128-I154 HydrophobicContact CG1-CD1 4.41Å; I128-I154 HydrophobicContact CG1-CG1 4.35Å; L132-I154 HydrophobicContact CD1-CD1 4.01Å; L132-I154 HydrophobicContact CD1-CG1 3.97Å; A146-I154 HydrophobicContact CB-CG2 3.67Å; L150-I154 WeakPolarHBondContact O-CG2 3.14Å; L150-I154 PolarHBondContact O-N 2.9Å; I154-G156 PolarHBondContact O-N 3.13Å; I154-L157 HydrophobicContact CG1-CB 4.29Å; I154-L157 HydrophobicContact CG1-CD1 4.42Å; I154-L157 WeakPolarHBondContact O-CB 3.44Å; I154-L157 PolarHBondContact O-N 3.43Å; I154-L157 VanDerWaalsContact O-N 3.08Å; I154-Y158 HydrophobicContact CB-CE1 4.46Å; I154-Y158 HydrophobicContact CD1-CD1 3.94Å; I154-Y158 HydrophobicContact CD1-CE1 3.78Å; I154-Y158 HydrophobicContact CG1-CD1 3.84Å; I154-Y158 HydrophobicContact CG1-CE1 3.82Å; I154-Y158 HydrophobicContact CG2-CE1 3.89Å
155S92.6Very high95.4Very high93 Ų9360.5 Ų60.565%0.6537%0.366SS*.BIsolated β-bridgetrans-56.8121.9-179.4176.50000111.7A151 L157A151-S155 VanDerWaalsContact O-CB 3.27Å; A151-S155 WeakPolarHBondContact O-CB 3.36Å; A151-S155 PolarHBondContact O-N 3.29Å; A151-S155 VanDerWaalsContact O-N 3.16Å; S155-L157 VanDerWaalsContact C-N 3.26Å; S155-L157 PolarHBondContact O-N 3.43Å
156G93.8Very high95.5Very high56 Ų5657.2 Ų57.258%0.57735%0.353SS*.THydrogen-bonded Turntrans81.6-5.3178.300000115I154I154-G156 PolarHBondContact O-N 3.13Å
157L97.1Very high95.5Very high55 Ų5558.8 Ų58.829%0.28837%0.371SS..THydrogen-bonded Turntrans-78.8-31.1175.1-62.7-171.8000112.4I128 L132 I154 S155I128-L157 HydrophobicContact CG1-CD1 4.16Å; I128-L157 HydrophobicContact CG2-CD1 4.02Å; L132-L157 HydrophobicContact CB-CB 4.06Å; L132-L157 HydrophobicContact CB-CD1 4.47Å; L132-L157 HydrophobicContact CD1-CB 3.81Å; L132-L157 HydrophobicContact CD1-CD1 4.39Å; I154-L157 HydrophobicContact CG1-CB 4.29Å; I154-L157 HydrophobicContact CG1-CD1 4.42Å; I154-L157 WeakPolarHBondContact O-CB 3.44Å; I154-L157 PolarHBondContact O-N 3.43Å; I154-L157 VanDerWaalsContact O-N 3.08Å; S155-L157 VanDerWaalsContact C-N 3.26Å; S155-L157 PolarHBondContact O-N 3.43Å
158Y98.3Very high95.6Very high29 Ų2961.2 Ų61.211%0.11439%0.39CS..BIsolated β-bridgetrans-125.7159.5162.174.2-82.8000109.3L115 I139 S141 I144 I154L115-Y158 HydrophobicContact CD1-CG 4.43Å; I139-Y158 CarbonylContact O-C 3.47Å; I139-Y158 VanDerWaalsContact O-CA 3.25Å; I139-Y158 WeakPolarHBondContact O-CA 3.18Å; I139-Y158 WeakPolarHBondContact O-CB 3.5Å; S141-Y158 WeakPolarHBondContact O-CE2 3.01Å; I144-Y158 HydrophobicContact CB-CE2 4.16Å; I144-Y158 HydrophobicContact CG2-CE2 4.48Å; I144-Y158 PolarHBondContact O-OH 3.33Å; I144-Y158 VanDerWaalsContact O-OH 3.06Å; I154-Y158 HydrophobicContact CB-CE1 4.46Å; I154-Y158 HydrophobicContact CD1-CD1 3.94Å; I154-Y158 HydrophobicContact CD1-CE1 3.78Å; I154-Y158 HydrophobicContact CG1-CD1 3.84Å; I154-Y158 HydrophobicContact CG1-CE1 3.82Å; I154-Y158 HydrophobicContact CG2-CE1 3.89Å
159L98.7Very high95.8Very high54 Ų5462 Ų6228%0.28338%0.379SS..BIsolated β-bridgetrans-126.7150.9-175-59.3171.7000110.9I139 L140 S141 Y161 K162I139-L159 PolarHBondContact O-N 2.69Å; L140-L159 CarbonylContact C-O 3.55Å; L140-L159 WeakPolarHBondContact CA-O 3.36Å; L140-L159 HydrophobicContact CD2-CB 3.99Å; S141-L159 PolarHBondContact N-O 3.38Å; L159-Y161 VanDerWaalsContact C-N 3.29Å; L159-Y161 WeakPolarHBondContact CB-O 3.37Å; L159-Y161 PolarHBondContact O-N 3.3Å; L159-K162 HydrophobicContact CD1-CD 3.92Å
160P98.7Very high96.1Very high38 Ų3859.6 Ų59.625%0.24736%0.362CS..SBendtrans-65.1-37.2171.425.8-33.3000111.8A142 G175 E203A142-P160 HydrophobicContact CB-CB 3.86Å; P160-G175 PolarHBondContact O-N 2.89Å; P160-E203 HydrophobicContact CB-CG 4.05Å
161Y98.9Very high96.5Very high38 Ų3859 Ų5915%0.14936%0.359CS..EExtended strand (participates in β ladder)trans-150.9165.9178.166.3-94.2000111.4L159 V163 I173 E203 K206 L207L159-Y161 VanDerWaalsContact C-N 3.29Å; L159-Y161 WeakPolarHBondContact CB-O 3.37Å; L159-Y161 PolarHBondContact O-N 3.3Å; Y161-V163 HydrophobicContact CD2-CG2 4.38Å; Y161-V163 HydrophobicContact CE2-CG2 4.33Å; Y161-I173 CarbonylContact C-O 3.57Å; Y161-I173 WeakPolarHBondContact CA-O 3.45Å; Y161-I173 WeakPolarHBondContact CB-O 3.46Å; Y161-E203 HydrophobicContact CD1-CB 4.17Å; Y161-E203 WeakPolarHBondContact CD1-OE2 3.04Å; Y161-E203 WeakPolarHBondContact CE1-OE2 3.33Å; Y161-K206 HydrophobicContact CE1-CD 3.99Å; Y161-K206 WeakPolarHBondContact OH-CE 3.37Å; Y161-K206 PolarHBondContact OH-NZ 3.43Å; Y161-L207 HydrophobicContact CD2-CD1 4.47Å; Y161-L207 HydrophobicContact CD2-CD2 3.53Å; Y161-L207 HydrophobicContact CD2-CG 4.13Å; Y161-L207 HydrophobicContact CE2-CD2 3.7Å; Y161-L207 HydrophobicContact CE2-CG 4.4Å; Y161-L207 HydrophobicContact CG-CD1 4.37Å; Y161-L207 HydrophobicContact CG-CD2 4.19Å; Y161-L207 HydrophobicContact CG-CG 4.3Å
162K98.9Very high96.8Very high86 Ų8657.2 Ų57.237%0.37434%0.344SS..EExtended strand (participates in β ladder)trans-136.2141.1166.6-167.974.7171.6-1730110.4P138 L140 L159 L164 I173P138-K162 HydrophobicContact CB-CB 4.01Å; P138-K162 HydrophobicContact CB-CD 4.22Å; P138-K162 HydrophobicContact CB-CG 4Å; P138-K162 HydrophobicContact CG-CB 4.08Å; P138-K162 HydrophobicContact CG-CG 3.94Å; L140-K162 HydrophobicContact CD2-CB 4.08Å; L159-K162 HydrophobicContact CD1-CD 3.92Å; K162-L164 HydrophobicContact CG-CD2 3.6Å; K162-L164 HydrophobicContact CG-CG 4.22Å; K162-I173 PolarHBondContact N-O 3.22Å; K162-I173 PolarHBondContact O-N 3.48Å
163V98.9Very high97.1Very high50 Ų5052.5 Ų52.530%0.30331%0.312SS..EExtended strand (participates in β ladder)trans-97.7120.5168.7-175.80000107.7Y161 V170 L207 V212Y161-V163 HydrophobicContact CD2-CG2 4.38Å; Y161-V163 HydrophobicContact CE2-CG2 4.33Å; V163-V170 HydrophobicContact CG1-CB 3.78Å; V163-V170 HydrophobicContact CG1-CG1 4.24Å; V163-V170 HydrophobicContact CG1-CG2 4.25Å; V163-L207 HydrophobicContact CG2-CD2 3.55Å; V163-V212 HydrophobicContact CG1-CG2 3.96Å; V163-V212 HydrophobicContact CG2-CG2 3.88Å
164L98.7Very high97.4Very high22 Ų2247.4 Ų47.412%0.11529%0.288CS..EExtended strand (participates in β ladder)trans-111.8134.5-178.2-62.8-177000110.7L79 D111 K162 V170 V171 I173L79-L164 HydrophobicContact CD2-CD1 4Å; D111-L164 HydrophobicContact CB-CD1 4.11Å; D111-L164 WeakPolarHBondContact O-CD1 3.18Å; K162-L164 HydrophobicContact CG-CD2 3.6Å; K162-L164 HydrophobicContact CG-CG 4.22Å; L164-V170 WeakPolarHBondContact O-CA 3.49Å; L164-V171 PolarHBondContact N-O 2.76Å; L164-V171 PolarHBondContact O-N 2.9Å; L164-I173 HydrophobicContact CD1-CD1 3.61Å; L164-I173 HydrophobicContact CG-CD1 4.36Å
165P98.4Very high97.7Very high106 Ų10647.2 Ų47.269%0.68829%0.287SS*.EExtended strand (participates in β ladder)trans-72.7134.5169.830.8-32.7000110.2
166V98.1Very high98Very high9 Ų942.8 Ų42.86%0.05526%0.256CS..EExtended strand (participates in β ladder)trans-137.4102.4176.1-171.90000108.5W27 L29 N77 L79 D168 E169 V171W27-V166 HydrophobicContact CH2-CB 4.12Å; W27-V166 HydrophobicContact CH2-CG1 4.1Å; W27-V166 HydrophobicContact CZ2-CB 3.94Å; W27-V166 HydrophobicContact CZ2-CG1 3.82Å; W27-V166 WeakPolarHBondContact CZ2-O 2.95Å; L29-V166 HydrophobicContact CD1-CG1 4.08Å; N77-V166 HydrophobicContact CB-CG1 3.69Å; L79-V166 HydrophobicContact CD1-CG2 4.14Å; L79-V166 HydrophobicContact CD2-CG2 3.79Å; L79-V166 HydrophobicContact CG-CG2 3.98Å; V166-D168 PolarHBondContact O-N 2.77Å; V166-E169 PolarHBondContact N-O 3.48Å; V166-E169 PolarHBondContact O-N 2.8Å; V166-E169 VanDerWaalsContact O-N 3.16Å; V166-V171 HydrophobicContact CB-CG2 4.45Å; V166-V171 HydrophobicContact CG2-CB 4.43Å; V166-V171 HydrophobicContact CG2-CG2 3.97Å
167G95.2Very high98.1Very high57 Ų5740.1 Ų40.159%0.58823%0.228SC*.THydrogen-bonded Turntrans61.2-128.7-167.100000110.3
168D93.9Very high97.6Very high171 Ų17137.6 Ų37.691%0.91422%0.215SC*.THydrogen-bonded Turntrans-90.1-0.2177.5-59.7-44.7000113.4V166V166-D168 PolarHBondContact O-N 2.77Å
169E97.9Very high97.1Very high69 Ų6941.4 Ų41.432%0.32223%0.233SC..EExtended strand (participates in β ladder)trans-107.1171-178.3-68.4-71140.400111.9W27 V166 K214W27-E169 HydrophobicContact CD2-CB 4.37Å; W27-E169 HydrophobicContact CD2-CG 3.98Å; W27-E169 HydrophobicContact CG-CG 4Å; W27-E169 HydrophobicContact CH2-CB 4.38Å; W27-E169 HydrophobicContact CZ2-CB 3.83Å; W27-E169 HydrophobicContact CZ2-CG 4.27Å; V166-E169 PolarHBondContact N-O 3.48Å; V166-E169 PolarHBondContact O-N 2.8Å; V166-E169 VanDerWaalsContact O-N 3.16Å; E169-K214 WeakPolarHBondContact OE2-CE 3.22Å; E169-K214 IonicContact OE2-NZ 3.29Å; E169-K214 PolarHBondContact OE2-NZ 3.08Å
170V98.5Very high96Very high58 Ų5842.2 Ų42.235%0.35224%0.235SC..EExtended strand (participates in β ladder)trans-123.1143.3171-65.80000111.4V163 L164 V212V163-V170 HydrophobicContact CG1-CB 3.78Å; V163-V170 HydrophobicContact CG1-CG1 4.24Å; V163-V170 HydrophobicContact CG1-CG2 4.25Å; L164-V170 WeakPolarHBondContact O-CA 3.49Å; V170-V212 HydrophobicContact CG2-CG2 4.43Å
171V98.9Very high94.8Very high1 Ų140.4 Ų40.41%0.00622%0.223CC..EExtended strand (participates in β ladder)trans-122.1125.4176.3-178.10000109.1W27 L29 L79 L164 V166 I173 I216W27-V171 HydrophobicContact CH2-CG2 3.76Å; W27-V171 HydrophobicContact CZ3-CG2 4.19Å; L29-V171 HydrophobicContact CD2-CG2 4.28Å; L79-V171 HydrophobicContact CD1-CB 4.23Å; L79-V171 HydrophobicContact CD1-CG1 4.08Å; L79-V171 HydrophobicContact CD1-CG2 4.44Å; L164-V171 PolarHBondContact N-O 2.76Å; L164-V171 PolarHBondContact O-N 2.9Å; V166-V171 HydrophobicContact CB-CG2 4.45Å; V166-V171 HydrophobicContact CG2-CB 4.43Å; V166-V171 HydrophobicContact CG2-CG2 3.97Å; V171-I173 HydrophobicContact CG1-CG1 4.42Å; V171-I216 HydrophobicContact CG1-CD1 3.66Å; V171-I216 HydrophobicContact CG1-CG1 3.95Å
172G98.9Very high93.8Very high0 Ų041.4 Ų41.40%023%0.234CC..EExtended strand (participates in β ladder)trans-84.8130.3171.900000110.5K214 I215 I216G172-K214 PolarHBondContact N-O 3.18Å; G172-I215 CarbonylContact O-C 3.45Å; G172-I215 WeakPolarHBondContact O-CA 3.42Å; G172-I216 PolarHBondContact O-N 3.4Å
173I98.9Very high92.1Very high0 Ų042.6 Ų42.60%024%0.239CC..EExtended strand (participates in β ladder)trans-119.7118.5175.5-50.7-178.2000107.9L79 L81 A112 L140 Y161 K162 L164 V171 I216 L218L79-I173 HydrophobicContact CD1-CD1 4.27Å; L81-I173 HydrophobicContact CD1-CD1 4.41Å; L81-I173 HydrophobicContact CD2-CD1 3.63Å; A112-I173 HydrophobicContact CB-CD1 4.08Å; L140-I173 HydrophobicContact CD1-CB 3.95Å; L140-I173 HydrophobicContact CD1-CG2 3.53Å; Y161-I173 CarbonylContact C-O 3.57Å; Y161-I173 WeakPolarHBondContact CA-O 3.45Å; Y161-I173 WeakPolarHBondContact CB-O 3.46Å; K162-I173 PolarHBondContact N-O 3.22Å; K162-I173 PolarHBondContact O-N 3.48Å; L164-I173 HydrophobicContact CD1-CD1 3.61Å; L164-I173 HydrophobicContact CG-CD1 4.36Å; V171-I173 HydrophobicContact CG1-CG1 4.42Å; I173-I216 CarbonylContact C-O 3.57Å; I173-I216 WeakPolarHBondContact CA-O 3.4Å; I173-I216 HydrophobicContact CG1-CB 4.49Å; I173-L218 HydrophobicContact CG2-CB 3.7Å; I173-L218 HydrophobicContact CG2-CD2 4Å
174V98.9Very high90.4Very high0 Ų041.5 Ų41.50%023%0.232CC..EExtended strand (participates in β ladder)trans-108.5129.6178.763.90000110A142 L200 E203 V204 I215 I216 A217 L218A142-V174 HydrophobicContact CB-CG2 4.13Å; V174-L200 HydrophobicContact CB-CD2 4.15Å; V174-L200 HydrophobicContact CG1-CD2 3.79Å; V174-L200 HydrophobicContact CG2-CD2 3.36Å; V174-E203 HydrophobicContact CG2-CB 3.95Å; V174-V204 HydrophobicContact CG1-CG2 3.95Å; V174-I215 HydrophobicContact CG1-CG2 4.32Å; V174-I216 PolarHBondContact N-O 3.31Å; V174-A217 HydrophobicContact CG1-CB 4.09Å; V174-A217 WeakPolarHBondContact O-CA 3.25Å; V174-L218 PolarHBondContact O-N 3Å
175G98.9Very high89.4Confident0 Ų041.6 Ų41.60%023%0.234CC..EExtended strand (participates in β ladder)trans-89.6149.8-17500000113.6A142 P160 L218A142-G175 WeakPolarHBondContact CB-O 3.27Å; A142-G175 PolarHBondContact N-O 3.2Å; P160-G175 PolarHBondContact O-N 2.89Å; G175-L218 CarbonylContact C-O 3.56Å; G175-L218 WeakPolarHBondContact CA-O 3.38Å
176Y98.9Very high88.4Confident0 Ų041.4 Ų41.40%023%0.227CC..EExtended strand (participates in β ladder)trans-149153.4165.760.4-83.8000112.1N143 E196 L200 A217 L218 G219 H220 S221 D226 I229 V239N143-Y176 WeakPolarHBondContact OD1-CA 3.48Å; Y176-E196 HydrophobicContact CD2-CG 4.17Å; Y176-L200 HydrophobicContact CD1-CD1 3.9Å; Y176-L200 HydrophobicContact CD1-CD2 4.27Å; Y176-L200 HydrophobicContact CG-CD1 4.12Å; Y176-A217 HydrophobicContact CD1-CB 4.43Å; Y176-A217 HydrophobicContact CE1-CB 3.96Å; Y176-L218 WeakPolarHBondContact CD1-O 3.5Å; Y176-L218 VanDerWaalsContact CE1-C 3.4Å; Y176-L218 PolarHBondContact N-O 2.99Å; Y176-L218 VanDerWaalsContact N-O 3.13Å; Y176-G219 VanDerWaalsContact CE1-CA 3.44Å; Y176-G219 VanDerWaalsContact CE1-N 3.3Å; Y176-G219 VanDerWaalsContact CE2-C 3.46Å; Y176-G219 CarbonylContact O-C 3.55Å; Y176-G219 WeakPolarHBondContact O-CA 3.35Å; Y176-H220 PolarHBondContact O-N 3.02Å; Y176-S221 WeakPolarHBondContact CD2-OG 3.3Å; Y176-D226 PolarHBondContact OH-OD1 3.2Å; Y176-I229 HydrophobicContact CD1-CD1 4.09Å; Y176-I229 HydrophobicContact CD2-CD1 3.67Å; Y176-I229 HydrophobicContact CE1-CD1 3.93Å; Y176-I229 HydrophobicContact CE2-CD1 3.48Å; Y176-I229 VanDerWaalsContact CE2-CD1 3.48Å; Y176-I229 HydrophobicContact CG-CD1 3.98Å; Y176-V239 VanDerWaalsContact OH-CG1 3.31Å; Y176-V239 WeakPolarHBondContact OH-CG1 3.41Å
177T95.5Very high87.5Confident0 Ų041.1 Ų41.10%023%0.226CC..EExtended strand (participates in β ladder)trans-135143.6-178.3-52.40000110.3L115 F120 S141 N143 I144 K179 F193L115-T177 WeakPolarHBondContact O-CB 3.23Å; L115-T177 WeakPolarHBondContact O-CG2 3.04Å; L115-T177 PolarHBondContact O-OG1 2.83Å; F120-T177 HydrophobicContact CE2-CG2 4.45Å; S141-T177 WeakPolarHBondContact CB-OG1 3.21Å; S141-T177 PolarHBondContact OG-OG1 3.03Å; N143-T177 PolarHBondContact ND2-O 2.93Å; N143-T177 PolarHBondContact OD1-N 3.03Å; N143-T177 PolarHBondContact OD1-O 2.63Å; I144-T177 HydrophobicContact CD1-CG2 4.29Å; T177-K179 PolarHBondContact O-N 3.13Å; T177-F193 HydrophobicContact CG2-CD1 4.26Å; T177-F193 HydrophobicContact CG2-CE1 3.87Å
178S86.8Confident86.9Confident2 Ų240.5 Ų40.51%0.01422%0.219CC..  trans-50.2129-177.4-178.40000113.2E180 T181 F193 H220 S221S178-E180 PolarHBondContact O-N 2.61Å; S178-E180 WeakPolarHBondContact OG-CB 3.28Å; S178-E180 PolarHBondContact OG-N 3.2Å; S178-T181 WeakPolarHBondContact O-CB 3.47Å; S178-T181 PolarHBondContact O-N 2.97Å; S178-T181 VanDerWaalsContact O-N 3.09Å; S178-T181 PolarHBondContact O-OG1 3.08Å; S178-F193 WeakPolarHBondContact O-CD1 3.19Å; S178-H220 WeakPolarHBondContact CA-O 3.37Å; S178-H220 VanDerWaalsContact CB-O 3.23Å; S178-H220 WeakPolarHBondContact CB-O 3.24Å; S178-H220 PolarHBondContact N-O 3.49Å; S178-S221 VanDerWaalsContact CA-OG 3.24Å; S178-S221 WeakPolarHBondContact CA-OG 3.2Å; S178-S221 PolarHBondContact N-OG 3.47Å
179K88.1Confident86.5Confident109 Ų10938.6 Ų38.647%0.47421%0.214SC..THydrogen-bonded Turntrans-60.3-19.2168.6-173173.5179.6-176.50113.3T177 T181 P182 E196T177-K179 PolarHBondContact O-N 3.13Å; K179-T181 VanDerWaalsContact C-N 3.27Å; K179-T181 PolarHBondContact O-N 2.89Å; K179-P182 WeakPolarHBondContact O-CD 3.49Å; K179-E196 PolarHBondContact N-OE1 3.22Å; K179-E196 VanDerWaalsContact N-OE1 3.13Å
180E76.7Confident86.1Confident71 Ų7138.9 Ų38.933%0.33222%0.218SC..THydrogen-bonded Turntrans-77.2-9.7176.8-65175.7-93.700112.9S178 P182 F183 L184 R441S178-E180 PolarHBondContact O-N 2.61Å; S178-E180 WeakPolarHBondContact OG-CB 3.28Å; S178-E180 PolarHBondContact OG-N 3.2Å; E180-P182 VanDerWaalsContact C-CD 3.41Å; E180-P182 VanDerWaalsContact C-N 3.34Å; E180-P182 VanDerWaalsContact O-N 3.1Å; E180-F183 WeakPolarHBondContact O-CA 3.26Å; E180-F183 WeakPolarHBondContact O-CB 3.37Å; E180-F183 PolarHBondContact O-N 3.05Å; E180-L184 HydrophobicContact CB-CD1 3.73Å; E180-L184 HydrophobicContact CB-CG 4.13Å; E180-L184 WeakPolarHBondContact O-CG 3.49Å; E180-L184 PolarHBondContact O-N 3.22Å; E180-R441 IonicContact OE2-CZ 3.36Å; E180-R441 IonicContact OE2-NH1 3.55Å; E180-R441 PolarHBondContact OE2-NH1 2.81Å; E180-R441 IonicContact OE2-NH2 3.33Å
181T73.6Confident85.7Confident0 Ų036.6 Ų36.60%020%0.203CC..Hα-helixtrans-47.6-42.1-175.9-58.40000115N117 F120 S178 K179 F183 L184 S185 P187 F193N117-T181 HydrophobicContact CB-CG2 3.9Å; F120-T181 HydrophobicContact CB-CG2 4.47Å; F120-T181 HydrophobicContact CD2-CG2 3.73Å; F120-T181 HydrophobicContact CE2-CG2 4.32Å; F120-T181 HydrophobicContact CG-CG2 4.25Å; S178-T181 WeakPolarHBondContact O-CB 3.47Å; S178-T181 PolarHBondContact O-N 2.97Å; S178-T181 VanDerWaalsContact O-N 3.09Å; S178-T181 PolarHBondContact O-OG1 3.08Å; K179-T181 VanDerWaalsContact C-N 3.27Å; K179-T181 PolarHBondContact O-N 2.89Å; T181-F183 PolarHBondContact O-N 3.13Å; T181-F183 VanDerWaalsContact O-N 3.1Å; T181-L184 PolarHBondContact O-N 2.78Å; T181-L184 VanDerWaalsContact O-N 3.08Å; T181-S185 PolarHBondContact O-N 3.42Å; T181-P187 HydrophobicContact CG2-CB 4.49Å; T181-P187 HydrophobicContact CG2-CG 4.23Å; T181-F193 VanDerWaalsContact CB-CE1 3.49Å; T181-F193 HydrophobicContact CG2-CD1 4.46Å; T181-F193 HydrophobicContact CG2-CE1 3.64Å; T181-F193 HydrophobicContact CG2-CE2 4.27Å; T181-F193 HydrophobicContact CG2-CZ 3.54Å
182P78Confident85.3Confident58 Ų5838.7 Ų38.738%0.37722%0.216SC..Hα-helixtrans-60.7-18.2176-2536.6000115.5K179 E180 P187 F193K179-P182 WeakPolarHBondContact O-CD 3.49Å; E180-P182 VanDerWaalsContact C-CD 3.41Å; E180-P182 VanDerWaalsContact C-N 3.34Å; E180-P182 VanDerWaalsContact O-N 3.1Å; P182-P187 HydrophobicContact CB-CG 4.26Å; P182-P187 HydrophobicContact CG-CG 4.24Å; P182-F193 HydrophobicContact CG-CD2 3.69Å; P182-F193 HydrophobicContact CG-CE2 4.17Å; P182-F193 HydrophobicContact CG-CG 4.36Å
183F62.1Low84.9Confident111 Ų11139.4 Ų39.449%0.48722%0.219SC..Hα-helixtrans-101.6-11.4178-50.9-70.8000113.2E180 T181 F500E180-F183 WeakPolarHBondContact O-CA 3.26Å; E180-F183 WeakPolarHBondContact O-CB 3.37Å; E180-F183 PolarHBondContact O-N 3.05Å; T181-F183 PolarHBondContact O-N 3.13Å; T181-F183 VanDerWaalsContact O-N 3.1Å; F183-F500 WeakPolarHBondContact O-CE2 3.3Å; F183-F500 WeakPolarHBondContact O-CZ 3.32Å
184L62.8Low84.7Confident28 Ų2842.9 Ų42.915%0.14724%0.236CC..Hα-helixtrans-111-20.9-174.3-59.7179.4000112.8N117 E180 T181N117-L184 HydrophobicContact CB-CB 4.42Å; E180-L184 HydrophobicContact CB-CD1 3.73Å; E180-L184 HydrophobicContact CB-CG 4.13Å; E180-L184 WeakPolarHBondContact O-CG 3.49Å; E180-L184 PolarHBondContact O-N 3.22Å; T181-L184 PolarHBondContact O-N 2.78Å; T181-L184 VanDerWaalsContact O-N 3.08Å
185S78.2Confident84.6Confident24 Ų2445.8 Ų45.817%0.16825%0.251CS..SBendtrans-147.7-161.4-176.1-166.30000111.2N117 F120 D121 T181 P187N117-S185 WeakPolarHBondContact O-CB 3.47Å; N117-S185 PolarHBondContact O-OG 2.94Å; N117-S185 VanDerWaalsContact O-OG 3.07Å; F120-S185 PolarHBondContact O-OG 3.17Å; D121-S185 VanDerWaalsContact CA-OG 3.25Å; D121-S185 WeakPolarHBondContact CA-OG 3.29Å; D121-S185 PolarHBondContact N-OG 2.74Å; D121-S185 WeakPolarHBondContact OD1-CB 3.29Å; D121-S185 PolarHBondContact OD1-OG 2.86Å; T181-S185 PolarHBondContact O-N 3.42Å; S185-P187 WeakPolarHBondContact O-CD 3.18Å
186N78.1Confident84.5Confident101 Ų10146.5 Ų46.554%0.5425%0.254SS..  trans-122.458.5-173.5-166.614.4000114F120 G123 G188F120-N186 CarbonylContact O-C 3.59Å; F120-N186 PolarHBondContact O-N 3.04Å; G123-N186 WeakPolarHBondContact CA-O 3.5Å; N186-G188 PolarHBondContact O-N 2.98Å; N186-G188 VanDerWaalsContact O-N 3.11Å
187P79.4Confident84.5Confident4 Ų448 Ų483%0.02626%0.262CS..  trans-72.4-2.5-179.633-38.1000114.3F120 V124 T181 P182 S185 L191 F193F120-P187 HydrophobicContact CB-CB 4.21Å; F120-P187 HydrophobicContact CD1-CB 3.88Å; F120-P187 HydrophobicContact CG-CB 4.08Å; V124-P187 VanDerWaalsContact CG2-O 3.32Å; V124-P187 WeakPolarHBondContact CG2-O 3.41Å; T181-P187 HydrophobicContact CG2-CB 4.49Å; T181-P187 HydrophobicContact CG2-CG 4.23Å; P182-P187 HydrophobicContact CB-CG 4.26Å; P182-P187 HydrophobicContact CG-CG 4.24Å; S185-P187 WeakPolarHBondContact O-CD 3.18Å; P187-L191 HydrophobicContact CB-CB 4.46Å; P187-L191 HydrophobicContact CB-CD1 4.17Å; P187-F193 HydrophobicContact CB-CE2 3.59Å; P187-F193 HydrophobicContact CB-CZ 3.8Å; P187-F193 HydrophobicContact CG-CE2 3.78Å; P187-F193 HydrophobicContact CG-CZ 4.23Å
188G81.1Confident84.6Confident43 Ų4352.7 Ų52.744%0.44329%0.291SS..  trans68.8-172.2-172.600000113.4N186N186-G188 PolarHBondContact O-N 2.98Å; N186-G188 VanDerWaalsContact O-N 3.11Å
189T86.3Confident85.2Confident132 Ų13252.9 Ų52.981%0.8129%0.293SS*.SBendtrans-94.7-8.2-175.354.80000114.1
190N90.4Very high85.7Confident75 Ų7547.7 Ų47.740%0.40127%0.27SS..SBendtrans-92.1-5.8-176.4-70.2-39.1000113.5K147 L150K147-N190 PolarHBondContact N-O 2.83Å; L150-N190 HydrophobicContact CB-CB 4.14Å; L150-N190 HydrophobicContact CD2-CB 3.67Å
191L88.6Confident86.7Confident9 Ų945.4 Ų45.45%0.04726%0.26CS..EExtended strand (participates in β ladder)trans-104.3132.1172-64.1-174.7000109.8F120 V124 I144 A146 L150 P187 F193F120-L191 HydrophobicContact CD1-CD1 4.03Å; F120-L191 HydrophobicContact CE1-CD1 3.48Å; F120-L191 VanDerWaalsContact CE1-CD1 3.48Å; F120-L191 HydrophobicContact CZ-CD1 4.38Å; V124-L191 HydrophobicContact CG2-CD1 3.6Å; V124-L191 HydrophobicContact CG2-CG 4.17Å; I144-L191 HydrophobicContact CG2-CB 4.41Å; I144-L191 HydrophobicContact CG2-CD1 4.38Å; I144-L191 HydrophobicContact CG2-CD2 4.07Å; A146-L191 HydrophobicContact CB-CD2 3.75Å; L150-L191 HydrophobicContact CD2-CD2 3.64Å; L150-L191 HydrophobicContact CD2-CG 3.93Å; P187-L191 HydrophobicContact CB-CB 4.46Å; P187-L191 HydrophobicContact CB-CD1 4.17Å; L191-F193 HydrophobicContact CB-CE2 3.91Å
192V91Very high87.9Confident46 Ų4648.8 Ų48.828%0.27928%0.282SS..EExtended strand (participates in β ladder)trans-110.4127.5172.21780000108.9I144 K145 K147 E194I144-V192 CarbonylContact C-O 3.52Å; I144-V192 WeakPolarHBondContact CA-O 3.24Å; K145-V192 PolarHBondContact N-O 3.13Å; K145-V192 PolarHBondContact O-N 2.83Å; K147-V192 HydrophobicContact CD-CG2 3.84Å; K147-V192 HydrophobicContact CG-CG2 4.49Å; K147-V192 VanDerWaalsContact NZ-CG2 3.31Å; V192-E194 HydrophobicContact CG1-CG 4.2Å
193F91.1Very high88.9Confident14 Ų1447.5 Ų47.56%0.06127%0.271CS..EExtended strand (participates in β ladder)trans-99103.4174-64.5-106.4000107.8F120 I144 T177 S178 T181 P182 P187 L191F120-F193 HydrophobicContact CD2-CZ 4.39Å; F120-F193 HydrophobicContact CE1-CZ 4.35Å; F120-F193 HydrophobicContact CE2-CE1 4.14Å; F120-F193 HydrophobicContact CE2-CZ 4.04Å; F120-F193 HydrophobicContact CZ-CE1 4.35Å; F120-F193 HydrophobicContact CZ-CZ 4.03Å; I144-F193 HydrophobicContact CD1-CD1 4.11Å; I144-F193 HydrophobicContact CD1-CE1 3.48Å; I144-F193 VanDerWaalsContact CD1-CE1 3.48Å; I144-F193 HydrophobicContact CD1-CZ 4.02Å; I144-F193 HydrophobicContact CG1-CD1 3.72Å; I144-F193 HydrophobicContact CG1-CE1 3.6Å; I144-F193 HydrophobicContact CG1-CG 4.44Å; I144-F193 HydrophobicContact CG1-CZ 4.22Å; T177-F193 HydrophobicContact CG2-CD1 4.26Å; T177-F193 HydrophobicContact CG2-CE1 3.87Å; S178-F193 WeakPolarHBondContact O-CD1 3.19Å; T181-F193 VanDerWaalsContact CB-CE1 3.49Å; T181-F193 HydrophobicContact CG2-CD1 4.46Å; T181-F193 HydrophobicContact CG2-CE1 3.64Å; T181-F193 HydrophobicContact CG2-CE2 4.27Å; T181-F193 HydrophobicContact CG2-CZ 3.54Å; P182-F193 HydrophobicContact CG-CD2 3.69Å; P182-F193 HydrophobicContact CG-CE2 4.17Å; P182-F193 HydrophobicContact CG-CG 4.36Å; P187-F193 HydrophobicContact CB-CE2 3.59Å; P187-F193 HydrophobicContact CB-CZ 3.8Å; P187-F193 HydrophobicContact CG-CE2 3.78Å; P187-F193 HydrophobicContact CG-CZ 4.23Å; L191-F193 HydrophobicContact CB-CE2 3.91Å
194E93.9Very high90.7Very high73 Ų7342.2 Ų42.234%0.34125%0.248SC..  trans-76.3166.4178.7-61.8-17815000110.9N143 K145 V192 E196 A199N143-E194 HydrophobicContact CB-CB 4.3Å; N143-E194 PolarHBondContact ND2-O 3.01Å; N143-E194 PolarHBondContact O-N 2.86Å; K145-E194 WeakPolarHBondContact CE-OE2 3.36Å; K145-E194 HydrophobicContact CG-CG 4.2Å; K145-E194 WeakPolarHBondContact CG-OE1 3.46Å; V192-E194 HydrophobicContact CG1-CG 4.2Å; E194-E196 PolarHBondContact O-N 3.02Å; E194-A199 HydrophobicContact CB-CB 4.46Å
195D96.7Very high92.4Very high62 Ų6244.3 Ų44.333%0.33226%0.259SS..  trans-59.6129.5169.8172.3-100.7000110.2I197 T198 A199D195-I197 PolarHBondContact O-N 2.97Å; D195-I197 PolarHBondContact OD1-N 3.23Å; D195-T198 PolarHBondContact O-N 2.99Å; D195-T198 VanDerWaalsContact OD1-CB 3.28Å; D195-T198 WeakPolarHBondContact OD1-CB 3.45Å; D195-T198 PolarHBondContact OD1-N 2.82Å; D195-T198 PolarHBondContact OD1-OG1 2.95Å; D195-A199 WeakPolarHBondContact O-CB 3.37Å; D195-A199 PolarHBondContact O-N 3.13Å
196E97.9Very high93.4Very high14 Ų1447.8 Ų47.87%0.06527%0.271CS..Hα-helixtrans-59.7-48-171.9-66.386.4161.300111.2Y176 K179 E194 T198 A199 L200 S221 T225 I229Y176-E196 HydrophobicContact CD2-CG 4.17Å; K179-E196 PolarHBondContact N-OE1 3.22Å; K179-E196 VanDerWaalsContact N-OE1 3.13Å; E194-E196 PolarHBondContact O-N 3.02Å; E196-T198 PolarHBondContact O-N 3.06Å; E196-A199 PolarHBondContact O-N 2.8Å; E196-L200 VanDerWaalsContact O-CB 3.24Å; E196-L200 WeakPolarHBondContact O-CB 3.19Å; E196-L200 WeakPolarHBondContact O-CG 3.45Å; E196-L200 PolarHBondContact O-N 3.1Å; E196-S221 WeakPolarHBondContact CG-OG 3.15Å; E196-S221 WeakPolarHBondContact OE1-CB 3.46Å; E196-S221 PolarHBondContact OE1-OG 3.21Å; E196-T225 HydrophobicContact CB-CG2 4.46Å; E196-T225 HydrophobicContact CG-CG2 4.31Å; E196-I229 HydrophobicContact CB-CD1 4.13Å
197I98.3Very high94.4Very high31 Ų3143 Ų4316%0.15925%0.245CC..Hα-helixtrans-65.6-43.6-176.3-60177.1000110.4D195 A199 L200 Q201 L228 I229 K232 V233D195-I197 PolarHBondContact O-N 2.97Å; D195-I197 PolarHBondContact OD1-N 3.23Å; I197-A199 VanDerWaalsContact C-N 3.32Å; I197-A199 PolarHBondContact O-N 2.69Å; I197-L200 PolarHBondContact O-N 2.73Å; I197-Q201 PolarHBondContact O-N 2.81Å; I197-Q201 VanDerWaalsContact O-N 3.15Å; I197-L228 HydrophobicContact CD1-CB 3.92Å; I197-I229 HydrophobicContact CG1-CG1 4.08Å; I197-K232 HydrophobicContact CD1-CB 4.22Å; I197-K232 HydrophobicContact CD1-CD 3.87Å; I197-K232 HydrophobicContact CD1-CG 4.41Å; I197-K232 HydrophobicContact CG2-CB 3.98Å; I197-V233 HydrophobicContact CB-CG2 4.36Å; I197-V233 HydrophobicContact CG1-CG2 4.41Å; I197-V233 HydrophobicContact CG2-CG2 3.93Å
198T98.2Very high95.3Very high99 Ų9946.4 Ų46.461%0.60726%0.26SS*.Hα-helixtrans-61.1-40.4177.6-58.90000111.8D195 E196 P202D195-T198 PolarHBondContact O-N 2.99Å; D195-T198 VanDerWaalsContact OD1-CB 3.28Å; D195-T198 WeakPolarHBondContact OD1-CB 3.45Å; D195-T198 PolarHBondContact OD1-N 2.82Å; D195-T198 PolarHBondContact OD1-OG1 2.95Å; E196-T198 PolarHBondContact O-N 3.06Å; T198-P202 WeakPolarHBondContact O-CD 3.43Å
199A98.4Very high96.1Very high7 Ų749.4 Ų49.46%0.05827%0.269CS..Hα-helixtrans-79.7-32.7179.800000113.5N143 E194 D195 E196 I197N143-A199 HydrophobicContact CB-CB 3.39Å; E194-A199 HydrophobicContact CB-CB 4.46Å; D195-A199 WeakPolarHBondContact O-CB 3.37Å; D195-A199 PolarHBondContact O-N 3.13Å; E196-A199 PolarHBondContact O-N 2.8Å; I197-A199 VanDerWaalsContact C-N 3.32Å; I197-A199 PolarHBondContact O-N 2.69Å
200L98.8Very high96.6Very high0 Ų047.7 Ų47.70%026%0.255CS..Hα-helixtrans-73.2-43.6-178.4-75.6172.8000112.7A142 V174 Y176 E196 I197 E203 V204 I229 V233A142-L200 HydrophobicContact CB-CD2 4.27Å; V174-L200 HydrophobicContact CB-CD2 4.15Å; V174-L200 HydrophobicContact CG1-CD2 3.79Å; V174-L200 HydrophobicContact CG2-CD2 3.36Å; Y176-L200 HydrophobicContact CD1-CD1 3.9Å; Y176-L200 HydrophobicContact CD1-CD2 4.27Å; Y176-L200 HydrophobicContact CG-CD1 4.12Å; E196-L200 VanDerWaalsContact O-CB 3.24Å; E196-L200 WeakPolarHBondContact O-CB 3.19Å; E196-L200 WeakPolarHBondContact O-CG 3.45Å; E196-L200 PolarHBondContact O-N 3.1Å; I197-L200 PolarHBondContact O-N 2.73Å; L200-E203 PolarHBondContact O-N 2.72Å; L200-E203 VanDerWaalsContact O-N 3.1Å; L200-V204 WeakPolarHBondContact O-CG2 3Å; L200-V204 PolarHBondContact O-N 2.7Å; L200-I229 HydrophobicContact CD1-CD1 3.77Å; L200-I229 HydrophobicContact CD1-CG1 3.91Å; L200-I229 HydrophobicContact CD1-CG2 3.8Å; L200-V233 HydrophobicContact CB-CG1 4.15Å; L200-V233 HydrophobicContact CB-CG2 4.15Å; L200-V233 HydrophobicContact CD1-CG2 4.39Å
201Q98.8Very high97Very high22 Ų2251 Ų5110%0.10327%0.273CS..Hα-helixtrans-55.5-47-172.2-174.668.467.200113.4I197 E203 V204 D205 R234I197-Q201 PolarHBondContact O-N 2.81Å; I197-Q201 VanDerWaalsContact O-N 3.15Å; Q201-E203 VanDerWaalsContact C-N 3.32Å; Q201-E203 PolarHBondContact O-N 2.9Å; Q201-V204 PolarHBondContact O-N 3.47Å; Q201-D205 PolarHBondContact NE2-OD1 3.14Å; Q201-D205 WeakPolarHBondContact O-CB 3.14Å; Q201-D205 PolarHBondContact O-N 3.12Å; Q201-R234 PolarHBondContact NE2-O 3.36Å; Q201-R234 VanDerWaalsContact NE2-O 3.1Å
202P98.8Very high97.4Very high72 Ų7250.8 Ų50.847%0.46827%0.272SS..Hα-helixtrans-63.1-34.9178.4-22.734.9000113.7T198 K206T198-P202 WeakPolarHBondContact O-CD 3.43Å; P202-K206 VanDerWaalsContact O-CB 3.31Å; P202-K206 WeakPolarHBondContact O-CB 3.37Å; P202-K206 PolarHBondContact O-N 3.28Å
203E98.8Very high97.8Very high31 Ų3150.6 Ų50.615%0.14527%0.269CS..Hα-helixtrans-72.7-36.5178.9-58.7-60.7166.500111.4A142 P160 Y161 V174 L200 Q201 K206 L207A142-E203 HydrophobicContact CB-CG 4.14Å; P160-E203 HydrophobicContact CB-CG 4.05Å; Y161-E203 HydrophobicContact CD1-CB 4.17Å; Y161-E203 WeakPolarHBondContact CD1-OE2 3.04Å; Y161-E203 WeakPolarHBondContact CE1-OE2 3.33Å; V174-E203 HydrophobicContact CG2-CB 3.95Å; L200-E203 PolarHBondContact O-N 2.72Å; L200-E203 VanDerWaalsContact O-N 3.1Å; Q201-E203 VanDerWaalsContact C-N 3.32Å; Q201-E203 PolarHBondContact O-N 2.9Å; E203-K206 WeakPolarHBondContact O-CB 3.11Å; E203-K206 PolarHBondContact O-N 3.34Å; E203-L207 WeakPolarHBondContact O-CG 3.38Å; E203-L207 PolarHBondContact O-N 3.05Å
204V98.8Very high98.1Very high0 Ų050 Ų500%027%0.267CS..Hα-helixtrans-66.9-44.4173.1175.50000111.1V174 L200 Q201 K206 L207 K208 I215 V233 R234 V236V174-V204 HydrophobicContact CG1-CG2 3.95Å; L200-V204 WeakPolarHBondContact O-CG2 3Å; L200-V204 PolarHBondContact O-N 2.7Å; Q201-V204 PolarHBondContact O-N 3.47Å; V204-K206 VanDerWaalsContact C-N 3.28Å; V204-K206 PolarHBondContact O-N 2.72Å; V204-L207 WeakPolarHBondContact O-CB 3.48Å; V204-L207 PolarHBondContact O-N 2.77Å; V204-K208 PolarHBondContact O-N 2.88Å; V204-I215 HydrophobicContact CG1-CD1 3.78Å; V204-I215 HydrophobicContact CG1-CG2 4.45Å; V204-I215 HydrophobicContact CG2-CG2 4.24Å; V204-V233 HydrophobicContact CB-CG1 4.3Å; V204-V233 HydrophobicContact CG2-CG1 3.88Å; V204-R234 WeakPolarHBondContact CG1-O 3.43Å; V204-V236 HydrophobicContact CG1-CG2 4.42Å; V204-V236 HydrophobicContact CG2-CG2 3.86Å
205D98.8Very high98.4Very high72 Ų7246.6 Ų46.639%0.38525%0.251SS..Hα-helixtrans-58.6-44.1174.8-68.6-19000110.3Q201 L207 K208 T209Q201-D205 PolarHBondContact NE2-OD1 3.14Å; Q201-D205 WeakPolarHBondContact O-CB 3.14Å; Q201-D205 PolarHBondContact O-N 3.12Å; D205-L207 PolarHBondContact O-N 3.14Å; D205-K208 PolarHBondContact O-N 3.37Å; D205-T209 WeakPolarHBondContact O-CG2 3.39Å; D205-T209 PolarHBondContact O-N 2.81Å
206K98.8Very high98.5Very high96 Ų9643.7 Ų43.742%0.41724%0.235SC..Hα-helixtrans-60.1-45.7175.6-174.7-179.4-179.6-167.50112.2Y161 P202 E203 V204 K208 T209 L210Y161-K206 HydrophobicContact CE1-CD 3.99Å; Y161-K206 WeakPolarHBondContact OH-CE 3.37Å; Y161-K206 PolarHBondContact OH-NZ 3.43Å; P202-K206 VanDerWaalsContact O-CB 3.31Å; P202-K206 WeakPolarHBondContact O-CB 3.37Å; P202-K206 PolarHBondContact O-N 3.28Å; E203-K206 WeakPolarHBondContact O-CB 3.11Å; E203-K206 PolarHBondContact O-N 3.34Å; V204-K206 VanDerWaalsContact C-N 3.28Å; V204-K206 PolarHBondContact O-N 2.72Å; K206-K208 VanDerWaalsContact C-N 3.3Å; K206-K208 PolarHBondContact O-N 3.13Å; K206-T209 PolarHBondContact O-N 2.86Å; K206-T209 VanDerWaalsContact O-N 3.11Å; K206-T209 PolarHBondContact O-OG1 2.88Å; K206-L210 HydrophobicContact CG-CD1 4.46Å; K206-L210 WeakPolarHBondContact O-CG 3.24Å; K206-L210 PolarHBondContact O-N 3.04Å; K206-L210 VanDerWaalsContact O-N 3.13Å
207L98.8Very high98.5Very high0 Ų043 Ų430%023%0.232CC..Hα-helixtrans-56.8-43175.3-78.3170.9000111.9Y161 V163 E203 V204 D205 T209 L210 V212 I215Y161-L207 HydrophobicContact CD2-CD1 4.47Å; Y161-L207 HydrophobicContact CD2-CD2 3.53Å; Y161-L207 HydrophobicContact CD2-CG 4.13Å; Y161-L207 HydrophobicContact CE2-CD2 3.7Å; Y161-L207 HydrophobicContact CE2-CG 4.4Å; Y161-L207 HydrophobicContact CG-CD1 4.37Å; Y161-L207 HydrophobicContact CG-CD2 4.19Å; Y161-L207 HydrophobicContact CG-CG 4.3Å; V163-L207 HydrophobicContact CG2-CD2 3.55Å; E203-L207 WeakPolarHBondContact O-CG 3.38Å; E203-L207 PolarHBondContact O-N 3.05Å; V204-L207 WeakPolarHBondContact O-CB 3.48Å; V204-L207 PolarHBondContact O-N 2.77Å; D205-L207 PolarHBondContact O-N 3.14Å; L207-T209 PolarHBondContact O-N 3.06Å; L207-L210 CarbonylContact O-C 3.58Å; L207-L210 PolarHBondContact O-N 3.06Å; L207-L210 VanDerWaalsContact O-N 3.1Å; L207-V212 HydrophobicContact CB-CB 4.27Å; L207-V212 HydrophobicContact CD2-CB 4.29Å; L207-V212 HydrophobicContact CD2-CG1 4.4Å; L207-V212 HydrophobicContact CD2-CG2 4.18Å; L207-V212 WeakPolarHBondContact O-CB 3.17Å; L207-V212 PolarHBondContact O-N 3.15Å; L207-I215 HydrophobicContact CB-CD1 3.73Å; L207-I215 HydrophobicContact CB-CG1 4.46Å; L207-I215 HydrophobicContact CD1-CD1 4.16Å; L207-I215 HydrophobicContact CD1-CG1 4.36Å; L207-I215 HydrophobicContact CD1-CG2 4.17Å
208K98.2Very high98.6Very high76 Ų7641.5 Ų41.533%0.3322%0.224SC..Hα-helixtrans-62.8-39.7175.4-63.2-66.6-174-1660111.8V204 D205 K206 L210 N211 V212 N213 I215 G235 D237V204-K208 PolarHBondContact O-N 2.88Å; D205-K208 PolarHBondContact O-N 3.37Å; K206-K208 VanDerWaalsContact C-N 3.3Å; K206-K208 PolarHBondContact O-N 3.13Å; K208-L210 PolarHBondContact O-N 2.85Å; K208-N211 PolarHBondContact O-N 3.21Å; K208-V212 WeakPolarHBondContact CD-O 3.24Å; K208-N213 PolarHBondContact NZ-O 2.78Å; K208-I215 HydrophobicContact CD-CD1 3.89Å; K208-I215 HydrophobicContact CG-CD1 4.1Å; K208-G235 WeakPolarHBondContact CE-O 3.49Å; K208-G235 PolarHBondContact NZ-O 3.19Å; K208-D237 IonicContact NZ-OD2 2.74Å
209T98.4Very high98.6Very high106 Ų10636.8 Ų36.865%0.6520%0.195SC*.Hα-helixtrans-64.7-22.4174.869.50000113.9D205 K206 L207 N211D205-T209 WeakPolarHBondContact O-CG2 3.39Å; D205-T209 PolarHBondContact O-N 2.81Å; K206-T209 PolarHBondContact O-N 2.86Å; K206-T209 VanDerWaalsContact O-N 3.11Å; K206-T209 PolarHBondContact O-OG1 2.88Å; L207-T209 PolarHBondContact O-N 3.06Å; T209-N211 VanDerWaalsContact C-N 3.25Å; T209-N211 PolarHBondContact O-N 3.23Å
210L97.8Very high98.5Very high97 Ų9736.5 Ų36.551%0.50819%0.193SC..THydrogen-bonded Turntrans-89.214.2174.7-63.1173.9000112.6K206 L207 K208 V212K206-L210 HydrophobicContact CG-CD1 4.46Å; K206-L210 WeakPolarHBondContact O-CG 3.24Å; K206-L210 PolarHBondContact O-N 3.04Å; K206-L210 VanDerWaalsContact O-N 3.13Å; L207-L210 CarbonylContact O-C 3.58Å; L207-L210 PolarHBondContact O-N 3.06Å; L207-L210 VanDerWaalsContact O-N 3.1Å; K208-L210 PolarHBondContact O-N 2.85Å; L210-V212 HydrophobicContact CB-CG2 4.43Å; L210-V212 PolarHBondContact O-N 3.31Å
211N97.6Very high98.1Very high144 Ų14436.7 Ų36.777%0.7719%0.194SC*.THydrogen-bonded Turntrans61.125.3-176.9-57.6-48.3000114.4K208 T209 N213K208-N211 PolarHBondContact O-N 3.21Å; T209-N211 VanDerWaalsContact C-N 3.25Å; T209-N211 PolarHBondContact O-N 3.23Å; N211-N213 PolarHBondContact O-N 2.68Å
212V98.6Very high97.6Very high5 Ų535.9 Ų35.93%0.0319%0.192CC..  trans-88.1106.5171.9-177.30000108.6V163 V170 L207 K208 L210 I215V163-V212 HydrophobicContact CG1-CG2 3.96Å; V163-V212 HydrophobicContact CG2-CG2 3.88Å; V170-V212 HydrophobicContact CG2-CG2 4.43Å; L207-V212 HydrophobicContact CB-CB 4.27Å; L207-V212 HydrophobicContact CD2-CB 4.29Å; L207-V212 HydrophobicContact CD2-CG1 4.4Å; L207-V212 HydrophobicContact CD2-CG2 4.18Å; L207-V212 WeakPolarHBondContact O-CB 3.17Å; L207-V212 PolarHBondContact O-N 3.15Å; K208-V212 WeakPolarHBondContact CD-O 3.24Å; L210-V212 HydrophobicContact CB-CG2 4.43Å; L210-V212 PolarHBondContact O-N 3.31Å; V212-I215 HydrophobicContact CG1-CG1 4.43Å
213N97.9Very high97.4Very high41 Ų4133.1 Ų33.122%0.21917%0.173CC..  trans-95.3-16.5-172.86711.5000114.7K208 N211 E296 R297K208-N213 PolarHBondContact NZ-O 2.78Å; N211-N213 PolarHBondContact O-N 2.68Å; N213-E296 PolarHBondContact ND2-O 2.74Å; N213-E296 VanDerWaalsContact ND2-O 3.15Å; N213-R297 WeakPolarHBondContact CB-O 3.47Å
214K98.8Very high97.1Very high2 Ų237 Ų371%0.00919%0.19CC..EExtended strand (participates in β ladder)trans-109.1115177.6-72.1173.5-89.6-65.90110.4W27 E169 G172 D237 F294W27-K214 HydrophobicContact CE3-CD 3.59Å; W27-K214 HydrophobicContact CZ3-CD 3.57Å; E169-K214 WeakPolarHBondContact OE2-CE 3.22Å; E169-K214 IonicContact OE2-NZ 3.29Å; E169-K214 PolarHBondContact OE2-NZ 3.08Å; G172-K214 PolarHBondContact N-O 3.18Å; K214-D237 WeakPolarHBondContact CA-OD2 3.39Å; K214-F294 HydrophobicContact CB-CE1 4.46Å; K214-F294 HydrophobicContact CD-CB 3.96Å; K214-F294 HydrophobicContact CD-CD1 4.07Å; K214-F294 HydrophobicContact CD-CD2 3.83Å; K214-F294 HydrophobicContact CD-CE1 4.48Å; K214-F294 HydrophobicContact CD-CE2 4.28Å; K214-F294 HydrophobicContact CD-CG 3.69Å; K214-F294 HydrophobicContact CG-CB 4.48Å; K214-F294 HydrophobicContact CG-CD1 3.78Å; K214-F294 HydrophobicContact CG-CD2 4.33Å; K214-F294 HydrophobicContact CG-CE1 3.94Å; K214-F294 HydrophobicContact CG-CE2 4.49Å; K214-F294 HydrophobicContact CG-CG 3.96Å; K214-F294 HydrophobicContact CG-CZ 4.3Å
215I98.9Very high97Very high1 Ų138.5 Ų38.51%0.00520%0.2CC..EExtended strand (participates in β ladder)trans-128.9123-171-58179.6000112G172 V174 V204 L207 K208 V212 V236 D237 V238G172-I215 CarbonylContact O-C 3.45Å; G172-I215 WeakPolarHBondContact O-CA 3.42Å; V174-I215 HydrophobicContact CG1-CG2 4.32Å; V204-I215 HydrophobicContact CG1-CD1 3.78Å; V204-I215 HydrophobicContact CG1-CG2 4.45Å; V204-I215 HydrophobicContact CG2-CG2 4.24Å; L207-I215 HydrophobicContact CB-CD1 3.73Å; L207-I215 HydrophobicContact CB-CG1 4.46Å; L207-I215 HydrophobicContact CD1-CD1 4.16Å; L207-I215 HydrophobicContact CD1-CG1 4.36Å; L207-I215 HydrophobicContact CD1-CG2 4.17Å; K208-I215 HydrophobicContact CD-CD1 3.89Å; K208-I215 HydrophobicContact CG-CD1 4.1Å; V212-I215 HydrophobicContact CG1-CG1 4.43Å; I215-V236 HydrophobicContact CG2-CG2 4.5Å; I215-D237 PolarHBondContact N-OD2 2.88Å; I215-D237 WeakPolarHBondContact O-CB 3.49Å; I215-D237 PolarHBondContact O-N 3.48Å; I215-V238 PolarHBondContact O-N 3.32Å
216I98.9Very high97Very high1 Ų135.1 Ų35.11%0.00518%0.182CC..EExtended strand (participates in β ladder)trans-103.5126.5173.5-57.2171.5000108.6L29 I31 L79 L81 V171 G172 I173 V174 V238 V240L29-I216 HydrophobicContact CD2-CD1 4.2Å; I31-I216 HydrophobicContact CD1-CD1 3.68Å; I31-I216 HydrophobicContact CD1-CG1 4.26Å; I31-I216 HydrophobicContact CG1-CD1 4.28Å; L79-I216 HydrophobicContact CD1-CD1 4.05Å; L81-I216 HydrophobicContact CD1-CD1 4.14Å; L81-I216 HydrophobicContact CD1-CG2 4.18Å; V171-I216 HydrophobicContact CG1-CD1 3.66Å; V171-I216 HydrophobicContact CG1-CG1 3.95Å; G172-I216 PolarHBondContact O-N 3.4Å; I173-I216 CarbonylContact C-O 3.57Å; I173-I216 WeakPolarHBondContact CA-O 3.4Å; I173-I216 HydrophobicContact CG1-CB 4.49Å; V174-I216 PolarHBondContact N-O 3.31Å; I216-V238 HydrophobicContact CG1-CB 4.36Å; I216-V240 HydrophobicContact CG2-CG2 4.09Å
217A98.9Very high97Very high0 Ų032.6 Ų32.60%017%0.171CC..EExtended strand (participates in β ladder)trans-88.6116.1162.800000108.7V174 Y176 I229 V236 V238 V239 V240V174-A217 HydrophobicContact CG1-CB 4.09Å; V174-A217 WeakPolarHBondContact O-CA 3.25Å; Y176-A217 HydrophobicContact CD1-CB 4.43Å; Y176-A217 HydrophobicContact CE1-CB 3.96Å; A217-I229 HydrophobicContact CB-CG2 4.04Å; A217-V236 HydrophobicContact CB-CG1 3.87Å; A217-V236 HydrophobicContact CB-CG2 4.23Å; A217-V238 PolarHBondContact N-O 2.81Å; A217-V239 HydrophobicContact CB-CG2 4.27Å; A217-V239 WeakPolarHBondContact O-CA 3.09Å; A217-V240 PolarHBondContact O-N 3.34Å
218L98.9Very high96.9Very high0 Ų036.1 Ų36.10%019%0.189CC..EExtended strand (participates in β ladder)trans-113.5123.4180177.966000108.7L81 A83 A112 A114 I173 V174 G175 Y176 V240L81-L218 HydrophobicContact CB-CD1 3.94Å; L81-L218 HydrophobicContact CB-CD2 4.04Å; L81-L218 HydrophobicContact CD1-CD1 4.45Å; L81-L218 HydrophobicContact CD2-CD2 4.44Å; A83-L218 HydrophobicContact CB-CD1 3.91Å; A112-L218 HydrophobicContact CB-CD2 4.2Å; A114-L218 HydrophobicContact CB-CD2 4.37Å; A114-L218 HydrophobicContact CB-CG 3.91Å; A114-L218 WeakPolarHBondContact CB-O 3.42Å; I173-L218 HydrophobicContact CG2-CB 3.7Å; I173-L218 HydrophobicContact CG2-CD2 4Å; V174-L218 PolarHBondContact O-N 3Å; G175-L218 CarbonylContact C-O 3.56Å; G175-L218 WeakPolarHBondContact CA-O 3.38Å; Y176-L218 WeakPolarHBondContact CD1-O 3.5Å; Y176-L218 VanDerWaalsContact CE1-C 3.4Å; Y176-L218 PolarHBondContact N-O 2.99Å; Y176-L218 VanDerWaalsContact N-O 3.13Å; L218-V240 WeakPolarHBondContact CA-O 3.47Å; L218-V240 HydrophobicContact CD1-CB 3.84Å; L218-V240 HydrophobicContact CD1-CG1 3.68Å
219G98.3Very high97Very high0 Ų032.5 Ų32.50%017%0.173CC..EExtended strand (participates in β ladder)trans-178.3-175.8-176.900000117.2Y176 V240 G241 G242Y176-G219 VanDerWaalsContact CE1-CA 3.44Å; Y176-G219 VanDerWaalsContact CE1-N 3.3Å; Y176-G219 VanDerWaalsContact CE2-C 3.46Å; Y176-G219 CarbonylContact O-C 3.55Å; Y176-G219 WeakPolarHBondContact O-CA 3.35Å; G219-V240 PolarHBondContact N-O 2.94Å; G219-G241 CarbonylContact O-C 3.56Å; G219-G241 VanDerWaalsContact O-CA 3.26Å; G219-G241 WeakPolarHBondContact O-CA 3.18Å; G219-G242 PolarHBondContact O-N 3.32Å; G219-G242 VanDerWaalsContact O-N 3.17Å
220H97.6Very high97Very high0 Ų027.4 Ų27.40%014%0.142CC..EExtended strand (participates in β ladder)trans-135.367-161.5-161.690.3000112.1D36 A83 D85 G116 N117 Y176 S178 H243D36-H220 IonicContact OD1-CE1 3.76Å; D36-H220 PolarHBondContact OD1-CE1 2.82Å; D36-H220 VanDerWaalsContact OD1-CE1 3.28Å; D36-H220 IonicContact OD1-NE2 2.7Å; D36-H220 IonicContact OD2-CE1 3.83Å; A83-H220 VanDerWaalsContact O-CB 3.31Å; A83-H220 WeakPolarHBondContact O-CB 3.48Å; A83-H220 PolarHBondContact O-ND1 3.04Å; D85-H220 VanDerWaalsContact CB-CE1 3.43Å; D85-H220 WeakPolarHBondContact CB-CE1 3.34Å; D85-H220 IonicContact OD1-CD2 2.99Å; D85-H220 IonicContact OD1-CE1 3.69Å; D85-H220 IonicContact OD1-NE2 2.81Å; D85-H220 PolarHBondContact OD1-NE2 3.05Å; D85-H220 IonicContact OD2-CE1 3.75Å; D85-H220 PolarHBondContact OD2-CE1 2.68Å; D85-H220 VanDerWaalsContact OD2-CE1 3.24Å; D85-H220 IonicContact OD2-NE2 2.73Å; D85-H220 PolarHBondContact OD2-NE2 3.17Å; G116-H220 VanDerWaalsContact CA-CD2 3.49Å; G116-H220 WeakPolarHBondContact CA-CD2 3.43Å; N117-H220 PolarHBondContact OD1-NE2 2.94Å; Y176-H220 PolarHBondContact O-N 3.02Å; S178-H220 WeakPolarHBondContact CA-O 3.37Å; S178-H220 VanDerWaalsContact CB-O 3.23Å; S178-H220 WeakPolarHBondContact CB-O 3.24Å; S178-H220 PolarHBondContact N-O 3.49Å; H220-H243 VanDerWaalsContact CD2-CB 3.49Å; H220-H243 WeakPolarHBondContact CD2-CB 3.2Å; H220-H243 AromaticContact CD2-CG 3.8Å; H220-H243 AromaticContact CD2-ND1 3.57Å; H220-H243 WeakPolarHBondContact CE1-CA 3.44Å; H220-H243 PolarHBondContact CE1-N 2.87Å; H220-H243 VanDerWaalsContact NE2-CA 3.26Å; H220-H243 WeakPolarHBondContact NE2-CA 3.33Å; H220-H243 VanDerWaalsContact NE2-CB 3.28Å; H220-H243 WeakPolarHBondContact NE2-CB 3.46Å; H220-H243 AromaticContact NE2-CG 3.61Å; H220-H243 AromaticContact NE2-ND1 3.2Å; H220-H243 PolarHBondContact NE2-ND1 3.08Å
221S90Very high97Very high4 Ų426.3 Ų26.33%0.02814%0.135CC..SBendtrans-129.37-179.4-63.70000114.5Y176 S178 E196 T225Y176-S221 WeakPolarHBondContact CD2-OG 3.3Å; S178-S221 VanDerWaalsContact CA-OG 3.24Å; S178-S221 WeakPolarHBondContact CA-OG 3.2Å; S178-S221 PolarHBondContact N-OG 3.47Å; E196-S221 WeakPolarHBondContact CG-OG 3.15Å; E196-S221 WeakPolarHBondContact OE1-CB 3.46Å; E196-S221 PolarHBondContact OE1-OG 3.21Å; S221-T225 WeakPolarHBondContact O-CB 3.09Å; S221-T225 PolarHBondContact O-OG1 3.13Å
222G87.8Confident97.1Very high6 Ų624 Ų246%0.06212%0.118CC..  trans86.1152.3178.200000113.6E224 T225 D226 G242G222-E224 PolarHBondContact O-N 2.8Å; G222-E224 VanDerWaalsContact O-N 3.08Å; G222-T225 WeakPolarHBondContact O-CA 3.45Å; G222-T225 WeakPolarHBondContact O-CB 3.31Å; G222-T225 PolarHBondContact O-N 2.89Å; G222-D226 PolarHBondContact O-N 3.1Å; G222-G242 VanDerWaalsContact CA-O 3.27Å; G222-G242 WeakPolarHBondContact CA-O 3.37Å; G222-G242 PolarHBondContact N-O 3.32Å
223F94.7Very high97.1Very high14 Ų1423.8 Ų23.86%0.06112%0.117CC..Hα-helixtrans-57-31.5-170.6-177.5-122.7000114.7D226 K227 S244 T246 L248 F265 V277F223-D226 WeakPolarHBondContact CA-OD2 3.24Å; F223-K227 HydrophobicContact CD1-CD 4.43Å; F223-K227 HydrophobicContact CE1-CD 3.95Å; F223-K227 HydrophobicContact CE2-CD 4.39Å; F223-K227 HydrophobicContact CE2-CG 4.2Å; F223-K227 HydrophobicContact CZ-CD 3.93Å; F223-K227 HydrophobicContact CZ-CG 4.23Å; F223-K227 WeakPolarHBondContact O-CE 3.44Å; F223-K227 WeakPolarHBondContact O-CG 3.31Å; F223-K227 PolarHBondContact O-N 3.36Å; F223-K227 VanDerWaalsContact O-N 3.08Å; F223-S244 WeakPolarHBondContact CB-OG 3.33Å; F223-S244 PolarHBondContact N-OG 3.09Å; F223-T246 HydrophobicContact CB-CG2 4.24Å; F223-T246 WeakPolarHBondContact CB-OG1 3.45Å; F223-T246 HydrophobicContact CD1-CG2 4.04Å; F223-T246 HydrophobicContact CD2-CG2 4.42Å; F223-T246 HydrophobicContact CE1-CG2 4.49Å; F223-T246 HydrophobicContact CG-CG2 3.98Å; F223-L248 HydrophobicContact CE2-CD1 3.91Å; F223-L248 HydrophobicContact CE2-CD2 4.38Å; F223-L248 HydrophobicContact CZ-CD1 4.34Å; F223-L248 HydrophobicContact CZ-CD2 4.05Å; F223-F265 HydrophobicContact CE2-CB 4.05Å; F223-F265 HydrophobicContact CE2-CD1 4.48Å; F223-F265 HydrophobicContact CE2-CG 4.23Å; F223-F265 HydrophobicContact CZ-CB 3.88Å; F223-F265 HydrophobicContact CZ-CD1 4.01Å; F223-F265 AromaticContact CZ-CD2 3.86Å; F223-F265 HydrophobicContact CZ-CD2 3.86Å; F223-F265 HydrophobicContact CZ-CE2 4.39Å; F223-F265 AromaticContact CZ-CG 3.64Å; F223-F265 HydrophobicContact CZ-CG 3.64Å; F223-V277 HydrophobicContact CD2-CG1 4.03Å; F223-V277 HydrophobicContact CE2-CB 4.43Å; F223-V277 HydrophobicContact CE2-CG1 3.83Å
224E93.6Very high97.1Very high111 Ų11128.3 Ų28.352%0.51913%0.131SC..Hα-helixtrans-67.1-43.8175-63.5-54.513200111.9G222 K227 L228G222-E224 PolarHBondContact O-N 2.8Å; G222-E224 VanDerWaalsContact O-N 3.08Å; E224-K227 VanDerWaalsContact CD-CE 3.5Å; E224-K227 PolarHBondContact O-N 2.7Å; E224-K227 WeakPolarHBondContact OE1-CE 3.25Å; E224-K227 IonicContact OE1-NZ 2.97Å; E224-K227 PolarHBondContact OE1-NZ 3.06Å; E224-K227 WeakPolarHBondContact OE2-CE 3.29Å; E224-K227 IonicContact OE2-NZ 3.34Å; E224-K227 PolarHBondContact OE2-NZ 2.9Å; E224-L228 WeakPolarHBondContact O-CG 3.4Å; E224-L228 PolarHBondContact O-N 2.77Å
225T95.4Very high97.1Very high33 Ų3328.8 Ų28.820%0.20214%0.136CC..Hα-helixtrans-67.7-39.9175.2-51.30000110.9E196 S221 G222 K227 L228 I229E196-T225 HydrophobicContact CB-CG2 4.46Å; E196-T225 HydrophobicContact CG-CG2 4.31Å; S221-T225 WeakPolarHBondContact O-CB 3.09Å; S221-T225 PolarHBondContact O-OG1 3.13Å; G222-T225 WeakPolarHBondContact O-CA 3.45Å; G222-T225 WeakPolarHBondContact O-CB 3.31Å; G222-T225 PolarHBondContact O-N 2.89Å; T225-K227 VanDerWaalsContact C-N 3.28Å; T225-K227 PolarHBondContact O-N 2.64Å; T225-L228 CarbonylContact O-C 3.56Å; T225-L228 WeakPolarHBondContact O-CA 3.43Å; T225-L228 WeakPolarHBondContact O-CB 3.37Å; T225-L228 PolarHBondContact O-N 2.93Å; T225-I229 HydrophobicContact CG2-CD1 4.05Å; T225-I229 HydrophobicContact CG2-CG1 4.39Å; T225-I229 WeakPolarHBondContact O-CG1 3.46Å; T225-I229 PolarHBondContact O-N 3.03Å
226D98.3Very high97.1Very high0 Ų028.8 Ų28.80%014%0.136CC..Hα-helixtrans-57.9-41.9176.9-56.7-15.8000111.4Y176 G222 F223 I229 A230 V239 G241 V277 Q279Y176-D226 PolarHBondContact OH-OD1 3.2Å; G222-D226 PolarHBondContact O-N 3.1Å; F223-D226 WeakPolarHBondContact CA-OD2 3.24Å; D226-I229 PolarHBondContact O-N 2.88Å; D226-A230 WeakPolarHBondContact O-CB 3.19Å; D226-A230 PolarHBondContact O-N 2.91Å; D226-V239 HydrophobicContact CB-CG1 3.81Å; D226-G241 WeakPolarHBondContact OD2-CA 3.35Å; D226-V277 HydrophobicContact CB-CG1 3.71Å; D226-Q279 PolarHBondContact OD2-NE2 2.79Å
227K98.6Very high97.1Very high44 Ų4428.8 Ų28.819%0.19114%0.136CC..Hα-helixtrans-64.2-39.9173.9-73.1-180-60.1-177.50112.2F223 E224 T225 A230 Q231 F265 V267F223-K227 HydrophobicContact CD1-CD 4.43Å; F223-K227 HydrophobicContact CE1-CD 3.95Å; F223-K227 HydrophobicContact CE2-CD 4.39Å; F223-K227 HydrophobicContact CE2-CG 4.2Å; F223-K227 HydrophobicContact CZ-CD 3.93Å; F223-K227 HydrophobicContact CZ-CG 4.23Å; F223-K227 WeakPolarHBondContact O-CE 3.44Å; F223-K227 WeakPolarHBondContact O-CG 3.31Å; F223-K227 PolarHBondContact O-N 3.36Å; F223-K227 VanDerWaalsContact O-N 3.08Å; E224-K227 VanDerWaalsContact CD-CE 3.5Å; E224-K227 PolarHBondContact O-N 2.7Å; E224-K227 WeakPolarHBondContact OE1-CE 3.25Å; E224-K227 IonicContact OE1-NZ 2.97Å; E224-K227 PolarHBondContact OE1-NZ 3.06Å; E224-K227 WeakPolarHBondContact OE2-CE 3.29Å; E224-K227 IonicContact OE2-NZ 3.34Å; E224-K227 PolarHBondContact OE2-NZ 2.9Å; T225-K227 VanDerWaalsContact C-N 3.28Å; T225-K227 PolarHBondContact O-N 2.64Å; K227-A230 PolarHBondContact O-N 3.02Å; K227-Q231 WeakPolarHBondContact O-CB 3.35Å; K227-Q231 PolarHBondContact O-N 3.48Å; K227-F265 HydrophobicContact CD-CD1 4.12Å; K227-F265 HydrophobicContact CD-CE1 3.66Å; K227-F265 HydrophobicContact CD-CZ 4.16Å; K227-F265 HydrophobicContact CG-CD1 4.22Å; K227-F265 HydrophobicContact CG-CE1 4.13Å; K227-V267 HydrophobicContact CB-CG2 4.1Å; K227-V267 HydrophobicContact CG-CG2 3.92Å
228L98.3Very high97.1Very high73 Ų7328.8 Ų28.838%0.38214%0.136SC..Hα-helixtrans-67.8-37.8177-68.2173.7000112I197 E224 T225 Q231 K232I197-L228 HydrophobicContact CD1-CB 3.92Å; E224-L228 WeakPolarHBondContact O-CG 3.4Å; E224-L228 PolarHBondContact O-N 2.77Å; T225-L228 CarbonylContact O-C 3.56Å; T225-L228 WeakPolarHBondContact O-CA 3.43Å; T225-L228 WeakPolarHBondContact O-CB 3.37Å; T225-L228 PolarHBondContact O-N 2.93Å; L228-Q231 PolarHBondContact O-N 2.99Å; L228-K232 WeakPolarHBondContact O-CB 3.25Å; L228-K232 WeakPolarHBondContact O-CG 3.5Å; L228-K232 PolarHBondContact O-N 3.24Å
229I98.7Very high97.1Very high0 Ų028.8 Ų28.80%014%0.136CC..Hα-helixtrans-61.9-51.2173.6-71.3166.8000109.7Y176 E196 I197 L200 A217 T225 D226 Q231 K232 V233 V239Y176-I229 HydrophobicContact CD1-CD1 4.09Å; Y176-I229 HydrophobicContact CD2-CD1 3.67Å; Y176-I229 HydrophobicContact CE1-CD1 3.93Å; Y176-I229 HydrophobicContact CE2-CD1 3.48Å; Y176-I229 VanDerWaalsContact CE2-CD1 3.48Å; Y176-I229 HydrophobicContact CG-CD1 3.98Å; E196-I229 HydrophobicContact CB-CD1 4.13Å; I197-I229 HydrophobicContact CG1-CG1 4.08Å; L200-I229 HydrophobicContact CD1-CD1 3.77Å; L200-I229 HydrophobicContact CD1-CG1 3.91Å; L200-I229 HydrophobicContact CD1-CG2 3.8Å; A217-I229 HydrophobicContact CB-CG2 4.04Å; T225-I229 HydrophobicContact CG2-CD1 4.05Å; T225-I229 HydrophobicContact CG2-CG1 4.39Å; T225-I229 WeakPolarHBondContact O-CG1 3.46Å; T225-I229 PolarHBondContact O-N 3.03Å; D226-I229 PolarHBondContact O-N 2.88Å; I229-Q231 PolarHBondContact O-N 3.4Å; I229-K232 PolarHBondContact O-N 3.28Å; I229-V233 HydrophobicContact CB-CG2 4.44Å; I229-V233 HydrophobicContact CG2-CB 4.39Å; I229-V233 HydrophobicContact CG2-CG2 3.99Å; I229-V233 WeakPolarHBondContact O-CB 3.11Å; I229-V233 PolarHBondContact O-N 3.41Å; I229-V239 HydrophobicContact CG2-CG2 4.04Å
230A98.8Very high97.1Very high0 Ų028.8 Ų28.80%014%0.136CC..Hα-helixtrans-57.2-35.9176.600000112.2D226 K227 V239 V267 S269 V275 V277D226-A230 WeakPolarHBondContact O-CB 3.19Å; D226-A230 PolarHBondContact O-N 2.91Å; K227-A230 PolarHBondContact O-N 3.02Å; A230-V239 HydrophobicContact CB-CG2 3.67Å; A230-V267 HydrophobicContact CB-CB 3.86Å; A230-V267 HydrophobicContact CB-CG1 4.02Å; A230-V267 HydrophobicContact CB-CG2 4.05Å; A230-S269 WeakPolarHBondContact O-CB 3.08Å; A230-V275 HydrophobicContact CB-CB 4.05Å; A230-V275 HydrophobicContact CB-CG1 3.69Å; A230-V277 HydrophobicContact CB-CG2 3.55Å
231Q98.8Very high97.2Very high73 Ų7328.8 Ų28.834%0.34114%0.136SC..Hα-helixtrans-73.1-48.5179.4-174.9179.6-7.500112.5K227 L228 I229 V267 S269 D270K227-Q231 WeakPolarHBondContact O-CB 3.35Å; K227-Q231 PolarHBondContact O-N 3.48Å; L228-Q231 PolarHBondContact O-N 2.99Å; I229-Q231 PolarHBondContact O-N 3.4Å; Q231-V267 HydrophobicContact CB-CG1 3.88Å; Q231-S269 WeakPolarHBondContact O-CA 3.49Å; Q231-D270 WeakPolarHBondContact CG-OD1 3.35Å; Q231-D270 PolarHBondContact NE2-OD1 3.48Å; Q231-D270 PolarHBondContact O-N 3.32Å
232K98.8Very high97.4Very high96 Ų9628.6 Ų28.642%0.41714%0.135SC..Hα-helixtrans-101-28.3-163.1-63-166.8-179.8-178.60114.7I197 L228 I229 R234I197-K232 HydrophobicContact CD1-CB 4.22Å; I197-K232 HydrophobicContact CD1-CD 3.87Å; I197-K232 HydrophobicContact CD1-CG 4.41Å; I197-K232 HydrophobicContact CG2-CB 3.98Å; L228-K232 WeakPolarHBondContact O-CB 3.25Å; L228-K232 WeakPolarHBondContact O-CG 3.5Å; L228-K232 PolarHBondContact O-N 3.24Å; I229-K232 PolarHBondContact O-N 3.28Å; K232-R234 PolarHBondContact O-N 3.23Å
233V98.8Very high97.5Very high1 Ų130.5 Ų30.51%0.00614%0.142CC..SBendtrans-83.499.4-176.5-172.90000109.4I197 L200 V204 I229 G235 V236I197-V233 HydrophobicContact CB-CG2 4.36Å; I197-V233 HydrophobicContact CG1-CG2 4.41Å; I197-V233 HydrophobicContact CG2-CG2 3.93Å; L200-V233 HydrophobicContact CB-CG1 4.15Å; L200-V233 HydrophobicContact CB-CG2 4.15Å; L200-V233 HydrophobicContact CD1-CG2 4.39Å; V204-V233 HydrophobicContact CB-CG1 4.3Å; V204-V233 HydrophobicContact CG2-CG1 3.88Å; I229-V233 HydrophobicContact CB-CG2 4.44Å; I229-V233 HydrophobicContact CG2-CB 4.39Å; I229-V233 HydrophobicContact CG2-CG2 3.99Å; I229-V233 WeakPolarHBondContact O-CB 3.11Å; I229-V233 PolarHBondContact O-N 3.41Å; V233-G235 PolarHBondContact O-N 2.86Å; V233-V236 HydrophobicContact CB-CG2 3.91Å; V233-V236 HydrophobicContact CG1-CG2 3.56Å; V233-V236 PolarHBondContact O-N 2.73Å
234R98.6Very high96.9Very high136 Ų13631.5 Ų31.551%0.51315%0.151SC..THydrogen-bonded Turntrans-63.5134.9-178.8-64.2179.8-60.1-76.3-5.3110.1Q201 V204 K232Q201-R234 PolarHBondContact NE2-O 3.36Å; Q201-R234 VanDerWaalsContact NE2-O 3.1Å; V204-R234 WeakPolarHBondContact CG1-O 3.43Å; K232-R234 PolarHBondContact O-N 3.23Å
235G98.3Very high96.6Very high12 Ų1227.3 Ų27.312%0.12413%0.132CC..THydrogen-bonded Turntrans91.2-8.917800000115.3K208 V233K208-G235 WeakPolarHBondContact CE-O 3.49Å; K208-G235 PolarHBondContact NZ-O 3.19Å; V233-G235 PolarHBondContact O-N 2.86Å
236V98.8Very high96.4Very high0 Ų026.5 Ų26.50%013%0.127CC..  trans-72.6131.3167.9171.60000109.3V204 I215 A217 V233 V238 V239 R273V204-V236 HydrophobicContact CG1-CG2 4.42Å; V204-V236 HydrophobicContact CG2-CG2 3.86Å; I215-V236 HydrophobicContact CG2-CG2 4.5Å; A217-V236 HydrophobicContact CB-CG1 3.87Å; A217-V236 HydrophobicContact CB-CG2 4.23Å; V233-V236 HydrophobicContact CB-CG2 3.91Å; V233-V236 HydrophobicContact CG1-CG2 3.56Å; V233-V236 PolarHBondContact O-N 2.73Å; V236-V238 WeakPolarHBondContact CG1-O 3.49Å; V236-V239 HydrophobicContact CG1-CG2 3.9Å; V236-R273 PolarHBondContact O-NH1 3.03Å; V236-R273 PolarHBondContact O-NH2 2.86Å
237D98.8Very high96.4Very high2 Ų226.9 Ų26.91%0.01113%0.128CC..  trans-103.3-26.3-177.5-58.1-53.7000112.3K208 K214 I215 R273 P276 F294 V300K208-D237 IonicContact NZ-OD2 2.74Å; K214-D237 WeakPolarHBondContact CA-OD2 3.39Å; I215-D237 PolarHBondContact N-OD2 2.88Å; I215-D237 WeakPolarHBondContact O-CB 3.49Å; I215-D237 PolarHBondContact O-N 3.48Å; D237-R273 IonicContact OD1-NH1 3.8Å; D237-R273 PolarHBondContact OD1-NH1 3.37Å; D237-R273 VanDerWaalsContact OD1-NH1 3.08Å; D237-P276 WeakPolarHBondContact O-CD 3.47Å; D237-F294 HydrophobicContact CB-CE1 3.86Å; D237-F294 HydrophobicContact CB-CZ 4.33Å; D237-V300 HydrophobicContact CB-CG2 3.99Å
238V98.9Very high96.4Very high0 Ų024.8 Ų24.80%012%0.119CC..EExtended strand (participates in β ladder)trans-148142.3-178.6-170.10000109.4I31 I215 I216 A217 V236 V240 P276 L290 I292 F294I31-V238 HydrophobicContact CD1-CG1 4.04Å; I31-V238 HydrophobicContact CD1-CG2 4.38Å; I215-V238 PolarHBondContact O-N 3.32Å; I216-V238 HydrophobicContact CG1-CB 4.36Å; A217-V238 PolarHBondContact N-O 2.81Å; V236-V238 WeakPolarHBondContact CG1-O 3.49Å; V238-V240 HydrophobicContact CG1-CG2 4.17Å; V238-P276 HydrophobicContact CG1-CG 4.22Å; V238-P276 HydrophobicContact CG2-CG 4.24Å; V238-L290 HydrophobicContact CG1-CD2 4.07Å; V238-I292 HydrophobicContact CB-CD1 4.23Å; V238-I292 HydrophobicContact CG1-CD1 3.97Å; V238-I292 HydrophobicContact CG2-CD1 3.21Å; V238-F294 HydrophobicContact CG2-CZ 4.37Å
239V98.9Very high96.4Very high0 Ų023.3 Ų23.30%011%0.109CC..EExtended strand (participates in β ladder)trans-115.9122.9168.2-173.10000110Y176 A217 D226 I229 A230 V236 V275 P276 V277 V278Y176-V239 VanDerWaalsContact OH-CG1 3.31Å; Y176-V239 WeakPolarHBondContact OH-CG1 3.41Å; A217-V239 HydrophobicContact CB-CG2 4.27Å; A217-V239 WeakPolarHBondContact O-CA 3.09Å; D226-V239 HydrophobicContact CB-CG1 3.81Å; I229-V239 HydrophobicContact CG2-CG2 4.04Å; A230-V239 HydrophobicContact CB-CG2 3.67Å; V236-V239 HydrophobicContact CG1-CG2 3.9Å; V239-V275 HydrophobicContact CG2-CG1 4.31Å; V239-P276 PolarHBondContact N-O 3.16Å; V239-V277 HydrophobicContact CB-CG1 4.34Å; V239-V277 HydrophobicContact CB-CG2 4.19Å; V239-V277 HydrophobicContact CG2-CG2 4.5Å; V239-V277 WeakPolarHBondContact O-CA 3.06Å; V239-V278 PolarHBondContact O-N 2.82Å
240V98.9Very high96.4Very high0 Ų026.3 Ų26.30%013%0.128CC..EExtended strand (participates in β ladder)trans-113114.5173179.10000107.6I31 H33 I216 A217 L218 G219 V238 V278I31-V240 HydrophobicContact CG2-CG2 4.14Å; H33-V240 HydrophobicContact CB-CG1 3.6Å; I216-V240 HydrophobicContact CG2-CG2 4.09Å; A217-V240 PolarHBondContact O-N 3.34Å; L218-V240 WeakPolarHBondContact CA-O 3.47Å; L218-V240 HydrophobicContact CD1-CB 3.84Å; L218-V240 HydrophobicContact CD1-CG1 3.68Å; G219-V240 PolarHBondContact N-O 2.94Å; V238-V240 HydrophobicContact CG1-CG2 4.17Å; V240-V278 HydrophobicContact CB-CG2 4.17Å; V240-V278 HydrophobicContact CG1-CG2 4.29Å; V240-V278 HydrophobicContact CG2-CG2 3.67Å
241G98.6Very high96.3Very high0 Ų029.2 Ų29.20%016%0.157CC..  trans-118.1176.1-169.200000115.1N35 A83 G219 D226 V278 Q279N35-G241 WeakPolarHBondContact CB-O 3.31Å; A83-G241 VanDerWaalsContact CB-C 3.48Å; A83-G241 WeakPolarHBondContact CB-O 3.45Å; G219-G241 CarbonylContact O-C 3.56Å; G219-G241 VanDerWaalsContact O-CA 3.26Å; G219-G241 WeakPolarHBondContact O-CA 3.18Å; D226-G241 WeakPolarHBondContact OD2-CA 3.35Å; G241-V278 PolarHBondContact N-O 2.82Å; G241-Q279 WeakPolarHBondContact O-CG 3.2Å
242G95.4Very high96.3Very high0 Ų032.9 Ų32.90%018%0.179CC..  trans-151.8-154.3173.300000112.4D36 G219 G222 S244 Q279D36-G242 WeakPolarHBondContact OD2-CA 3.13Å; G219-G242 PolarHBondContact O-N 3.32Å; G219-G242 VanDerWaalsContact O-N 3.17Å; G222-G242 VanDerWaalsContact CA-O 3.27Å; G222-G242 WeakPolarHBondContact CA-O 3.37Å; G222-G242 PolarHBondContact N-O 3.32Å; G242-S244 VanDerWaalsContact C-N 3.28Å; G242-S244 PolarHBondContact O-N 3.22Å; G242-Q279 PolarHBondContact O-NE2 2.98Å
243H90.4Very high96.2Very high45 Ų4530.9 Ų30.921%0.20818%0.176CC..SBendtrans80.1-49.7174-168.556.3000115.6D36 N117 H220 N245D36-H243 VanDerWaalsContact OD1-CA 3.3Å; D36-H243 WeakPolarHBondContact OD1-CA 3.47Å; D36-H243 PolarHBondContact OD1-N 3.48Å; D36-H243 PolarHBondContact OD2-N 3.33Å; N117-H243 PolarHBondContact OD1-CE1 2.86Å; N117-H243 PolarHBondContact OD1-ND1 3.12Å; H220-H243 VanDerWaalsContact CD2-CB 3.49Å; H220-H243 WeakPolarHBondContact CD2-CB 3.2Å; H220-H243 AromaticContact CD2-CG 3.8Å; H220-H243 AromaticContact CD2-ND1 3.57Å; H220-H243 WeakPolarHBondContact CE1-CA 3.44Å; H220-H243 PolarHBondContact CE1-N 2.87Å; H220-H243 VanDerWaalsContact NE2-CA 3.26Å; H220-H243 WeakPolarHBondContact NE2-CA 3.33Å; H220-H243 VanDerWaalsContact NE2-CB 3.28Å; H220-H243 WeakPolarHBondContact NE2-CB 3.46Å; H220-H243 AromaticContact NE2-CG 3.61Å; H220-H243 AromaticContact NE2-ND1 3.2Å; H220-H243 PolarHBondContact NE2-ND1 3.08Å; H243-N245 VanDerWaalsContact C-N 3.28Å; H243-N245 PolarHBondContact O-N 3.39Å
244S82.3Confident96.2Very high36 Ų3633.5 Ų33.525%0.25219%0.193SC..SBendtrans-88.16.6-175.152.80000113.6F223 G242 T246 Q279F223-S244 WeakPolarHBondContact CB-OG 3.33Å; F223-S244 PolarHBondContact N-OG 3.09Å; G242-S244 VanDerWaalsContact C-N 3.28Å; G242-S244 PolarHBondContact O-N 3.22Å; S244-T246 WeakPolarHBondContact CB-OG1 3.35Å; S244-T246 PolarHBondContact O-N 3.16Å; S244-T246 VanDerWaalsContact O-N 3.08Å; S244-T246 PolarHBondContact O-OG1 3.33Å; S244-T246 PolarHBondContact OG-OG1 3.16Å; S244-Q279 PolarHBondContact OG-NE2 3.36Å; S244-Q279 PolarHBondContact OG-OE1 3.39Å
245N86.3Confident96.1Very high22 Ų2228.1 Ų28.112%0.11818%0.176CC..  trans48.534.7-176.4-63.3-11000113.6D36 H243 F247 Y281 A282D36-N245 WeakPolarHBondContact CB-OD1 3.32Å; D36-N245 PolarHBondContact OD1-OD1 2.91Å; H243-N245 VanDerWaalsContact C-N 3.28Å; H243-N245 PolarHBondContact O-N 3.39Å; N245-F247 PolarHBondContact O-N 2.77Å; N245-Y281 CarbonylContact C-O 2.86Å; N245-Y281 VanDerWaalsContact CA-O 3.24Å; N245-Y281 WeakPolarHBondContact CA-O 3.5Å; N245-Y281 WeakPolarHBondContact O-CD2 3.27Å; N245-A282 HydrophobicContact CB-CB 4.04Å
246T91.9Very high95.8Very high16 Ų1634.6 Ų34.610%0.09820%0.201CC..  trans-74.9123.3-167.9-58.50000110.5F223 S244 L248 A260 Q279 Y281F223-T246 HydrophobicContact CB-CG2 4.24Å; F223-T246 WeakPolarHBondContact CB-OG1 3.45Å; F223-T246 HydrophobicContact CD1-CG2 4.04Å; F223-T246 HydrophobicContact CD2-CG2 4.42Å; F223-T246 HydrophobicContact CE1-CG2 4.49Å; F223-T246 HydrophobicContact CG-CG2 3.98Å; S244-T246 WeakPolarHBondContact CB-OG1 3.35Å; S244-T246 PolarHBondContact O-N 3.16Å; S244-T246 VanDerWaalsContact O-N 3.08Å; S244-T246 PolarHBondContact O-OG1 3.33Å; S244-T246 PolarHBondContact OG-OG1 3.16Å; T246-L248 HydrophobicContact CG2-CD2 4.03Å; T246-L248 HydrophobicContact CG2-CG 4.16Å; T246-A260 HydrophobicContact CG2-CB 3.77Å; T246-Q279 VanDerWaalsContact O-CB 3.31Å; T246-Q279 WeakPolarHBondContact O-CB 3.35Å; T246-Q279 PolarHBondContact OG1-OE1 3.32Å; T246-Y281 PolarHBondContact O-N 3.35Å
247F97.1Very high95.4Very high8 Ų835.3 Ų35.34%0.03520%0.204CC..BIsolated β-bridgetrans-92119.7171.5-176.3-123.4000109.8N245 Y249 P253 E257 P259 A260 Y281 Y286 P307N245-F247 PolarHBondContact O-N 2.77Å; F247-Y249 HydrophobicContact CE1-CD2 4.39Å; F247-Y249 HydrophobicContact CE1-CG 4.44Å; F247-Y249 AromaticContact CE2-CD2 3.91Å; F247-Y249 HydrophobicContact CE2-CD2 3.91Å; F247-Y249 AromaticContact CZ-CD2 3.48Å; F247-Y249 HydrophobicContact CZ-CD2 3.48Å; F247-Y249 VanDerWaalsContact CZ-CD2 3.48Å; F247-Y249 HydrophobicContact CZ-CE2 4.33Å; F247-Y249 AromaticContact CZ-CG 3.94Å; F247-Y249 HydrophobicContact CZ-CG 3.94Å; F247-P253 HydrophobicContact CE1-CB 3.83Å; F247-P253 HydrophobicContact CZ-CB 4.28Å; F247-E257 HydrophobicContact CB-CB 4.18Å; F247-E257 HydrophobicContact CD1-CB 3.42Å; F247-E257 VanDerWaalsContact CD1-CB 3.42Å; F247-E257 HydrophobicContact CD2-CB 4.46Å; F247-E257 HydrophobicContact CE1-CB 3.82Å; F247-E257 VanDerWaalsContact CE1-O 3.31Å; F247-E257 WeakPolarHBondContact CE1-O 3.45Å; F247-E257 HydrophobicContact CG-CB 3.78Å; F247-E257 HydrophobicContact CZ-CB 4.49Å; F247-P259 HydrophobicContact CD1-CB 4.3Å; F247-P259 HydrophobicContact CD1-CG 4.02Å; F247-P259 HydrophobicContact CE1-CB 4.49Å; F247-P259 HydrophobicContact CE1-CG 3.8Å; F247-P259 CarbonylContact O-C 3.56Å; F247-P259 WeakPolarHBondContact O-CA 3.45Å; F247-A260 PolarHBondContact O-N 3.33Å; F247-Y281 HydrophobicContact CB-CD2 4.09Å; F247-Y281 HydrophobicContact CB-CG 4.43Å; F247-Y286 HydrophobicContact CD2-CE2 4.42Å; F247-Y286 HydrophobicContact CE2-CD1 4.16Å; F247-Y286 HydrophobicContact CE2-CD2 4.42Å; F247-Y286 AromaticContact CE2-CE1 3.78Å; F247-Y286 HydrophobicContact CE2-CE1 3.78Å; F247-Y286 HydrophobicContact CE2-CE2 4.08Å; F247-Y286 HydrophobicContact CE2-CG 4.46Å; F247-Y286 AromaticContact CE2-CZ 3.75Å; F247-Y286 HydrophobicContact CZ-CE1 4.13Å; F247-P307 HydrophobicContact CE2-CB 4.45Å; F247-P307 HydrophobicContact CE2-CG 4.37Å
248L98.3Very high95.1Very high0 Ų041.2 Ų41.20%024%0.24CC..BIsolated β-bridgetrans-114.3139.1173.1-63.3176.5000108.8F223 T246 A260 G261 Y263 F265 P307F223-L248 HydrophobicContact CE2-CD1 3.91Å; F223-L248 HydrophobicContact CE2-CD2 4.38Å; F223-L248 HydrophobicContact CZ-CD1 4.34Å; F223-L248 HydrophobicContact CZ-CD2 4.05Å; T246-L248 HydrophobicContact CG2-CD2 4.03Å; T246-L248 HydrophobicContact CG2-CG 4.16Å; L248-A260 HydrophobicContact CD2-CB 4.43Å; L248-G261 WeakPolarHBondContact CA-O 3.44Å; L248-Y263 HydrophobicContact CB-CD2 3.97Å; L248-Y263 HydrophobicContact CB-CG 4.44Å; L248-F265 HydrophobicContact CD1-CB 4.02Å; L248-P307 WeakPolarHBondContact O-CD 3.24Å; L248-P307 WeakPolarHBondContact O-CG 3.24Å
249Y98.7Very high94.9Very high43 Ų4343.1 Ų43.117%0.16925%0.252CS..  trans-154.2140.6179.5-150.6-92.4000111.6F247 N252 P254 G261 N306 P307F247-Y249 HydrophobicContact CE1-CD2 4.39Å; F247-Y249 HydrophobicContact CE1-CG 4.44Å; F247-Y249 AromaticContact CE2-CD2 3.91Å; F247-Y249 HydrophobicContact CE2-CD2 3.91Å; F247-Y249 AromaticContact CZ-CD2 3.48Å; F247-Y249 HydrophobicContact CZ-CD2 3.48Å; F247-Y249 VanDerWaalsContact CZ-CD2 3.48Å; F247-Y249 HydrophobicContact CZ-CE2 4.33Å; F247-Y249 AromaticContact CZ-CG 3.94Å; F247-Y249 HydrophobicContact CZ-CG 3.94Å; Y249-N252 WeakPolarHBondContact CE1-O 3.49Å; Y249-P254 HydrophobicContact CE2-CG 4.04Å; Y249-G261 PolarHBondContact N-O 2.62Å; Y249-N306 HydrophobicContact CD2-CB 4.46Å; Y249-N306 HydrophobicContact CE2-CB 3.95Å; Y249-P307 WeakPolarHBondContact CE2-O 3.49Å
250T98.6Very high94.6Very high63 Ų6346.6 Ų46.639%0.38728%0.281SS..SBendtrans-107114.5172.3-64.80000109.5Y263 N306T250-Y263 PolarHBondContact OG1-N 3.24Å; T250-Y263 PolarHBondContact OG1-O 3.29Å; T250-N306 PolarHBondContact N-OD1 2.98Å; T250-N306 PolarHBondContact O-ND2 2.94Å
251G98.1Very high94.4Very high60 Ų6047.7 Ų47.762%0.61929%0.292SS*.SBendtrans103.3-153.2-17600000112.3
252N97.9Very high94.4Very high151 Ų15154.9 Ų54.981%0.80732%0.323SS*.SBendtrans-81.3121.2-179.6-65.6-27.6000110.3Y249Y249-N252 WeakPolarHBondContact CE1-O 3.49Å
253P97.6Very high94.6Very high53 Ų5355 Ų5534%0.34432%0.324SS..  trans-65.7144.118028.1-35.2000111.5F247 P259F247-P253 HydrophobicContact CE1-CB 3.83Å; F247-P253 HydrophobicContact CZ-CB 4.28Å; P253-P259 HydrophobicContact CB-CG 3.99Å; P253-P259 HydrophobicContact CG-CG 4.17Å
254P97.7Very high95Very high57 Ų5753.5 Ų53.537%0.3732%0.318SS..SBendtrans-89.4-1.6-170.336-38.3000114.6Y249 Y286 L309Y249-P254 HydrophobicContact CE2-CG 4.04Å; P254-Y286 HydrophobicContact CG-CE1 3.84Å; P254-L309 HydrophobicContact CB-CB 4.27Å; P254-L309 HydrophobicContact CB-CD2 4.03Å; P254-L309 HydrophobicContact CG-CB 3.9Å; P254-L309 HydrophobicContact CG-CD2 4.29Å
255S96.7Very high95.8Very high22 Ų2254.9 Ų54.915%0.15432%0.32CS..SBendtrans-149-159.1176.3-169.70000109.6E46 E257 K285 Y286E46-S255 PolarHBondContact OE1-OG 2.75Å; E46-S255 VanDerWaalsContact OE1-OG 3.06Å; S255-E257 WeakPolarHBondContact CB-OE2 3.18Å; S255-K285 PolarHBondContact OG-NZ 2.65Å; S255-Y286 WeakPolarHBondContact CB-OH 3.27Å
256K91.4Very high96.4Very high149 Ų14957.5 Ų57.565%0.64833%0.333SS*.SBendtrans-76.4-19.6-170.3-72176.7171.2159.10114.7E46 V258E46-K256 HydrophobicContact CG-CD 4.28Å; E46-K256 WeakPolarHBondContact OE2-CD 3.33Å; E46-K256 WeakPolarHBondContact OE2-CE 3.12Å; E46-K256 IonicContact OE2-NZ 2.91Å; E46-K256 PolarHBondContact OE2-NZ 2.63Å; K256-V258 PolarHBondContact O-N 2.56Å
257E91.2Very high96.7Very high15 Ų1557.4 Ų57.47%0.0733%0.332CS..PPolyproline II helixtrans-64.3129.5-178.6-68.468.6-152.500110.7F247 S255 Y281 K285 Y286F247-E257 HydrophobicContact CB-CB 4.18Å; F247-E257 HydrophobicContact CD1-CB 3.42Å; F247-E257 VanDerWaalsContact CD1-CB 3.42Å; F247-E257 HydrophobicContact CD2-CB 4.46Å; F247-E257 HydrophobicContact CE1-CB 3.82Å; F247-E257 VanDerWaalsContact CE1-O 3.31Å; F247-E257 WeakPolarHBondContact CE1-O 3.45Å; F247-E257 HydrophobicContact CG-CB 3.78Å; F247-E257 HydrophobicContact CZ-CB 4.49Å; S255-E257 WeakPolarHBondContact CB-OE2 3.18Å; E257-Y281 HydrophobicContact CG-CD1 4.02Å; E257-Y281 HydrophobicContact CG-CD2 3.82Å; E257-Y281 HydrophobicContact CG-CE1 3.79Å; E257-Y281 HydrophobicContact CG-CE2 3.59Å; E257-Y281 HydrophobicContact CG-CG 4.02Å; E257-K285 IonicContact OE1-NZ 3.45Å; E257-K285 PolarHBondContact OE1-NZ 2.8Å; E257-K285 WeakPolarHBondContact OE2-CE 3.46Å; E257-K285 IonicContact OE2-NZ 2.74Å; E257-K285 PolarHBondContact OE2-NZ 3.22Å; E257-Y286 HydrophobicContact CG-CE2 4.5Å; E257-Y286 PolarHBondContact OE2-OH 2.94Å; E257-Y286 VanDerWaalsContact OE2-OH 3.08Å
258V91.9Very high96.8Very high126 Ų12660.4 Ų60.476%0.76435%0.351SS*.PPolyproline II helixtrans-88.6122.9177.1-179.80000108.6K256 A260K256-V258 PolarHBondContact O-N 2.56Å; V258-A260 PolarHBondContact O-N 3.41Å
259P95.7Very high96.8Very high40 Ų4060.7 Ų60.726%0.2635%0.353SS..PPolyproline II helixtrans-63.7131.1179.5-21.632.2000112F247 P253F247-P259 HydrophobicContact CD1-CB 4.3Å; F247-P259 HydrophobicContact CD1-CG 4.02Å; F247-P259 HydrophobicContact CE1-CB 4.49Å; F247-P259 HydrophobicContact CE1-CG 3.8Å; F247-P259 CarbonylContact O-C 3.56Å; F247-P259 WeakPolarHBondContact O-CA 3.45Å; P253-P259 HydrophobicContact CB-CG 3.99Å; P253-P259 HydrophobicContact CG-CG 4.17Å
260A91Very high96.7Very high73 Ų7364 Ų6460%0.60337%0.374SS*.SBendtrans-75.5-15.9171.100000112.5T246 F247 L248 V258T246-A260 HydrophobicContact CG2-CB 3.77Å; F247-A260 PolarHBondContact O-N 3.33Å; L248-A260 HydrophobicContact CD2-CB 4.43Å; V258-A260 PolarHBondContact O-N 3.41Å
261G96.4Very high96.6Very high22 Ų2264.4 Ų64.423%0.22737%0.374CS..BIsolated β-bridgetrans-179.6-178-17900000111.8L248 Y249L248-G261 WeakPolarHBondContact CA-O 3.44Å; Y249-G261 PolarHBondContact N-O 2.62Å
262K98.6Very high96.6Very high151 Ų15164.2 Ų64.266%0.65737%0.371SS*.  trans-69.4153.3175.6-67.2-175.4-179.9-178.80111.1P264 F265K262-P264 CarbonylContact C-O 3.58Å; K262-P264 CarbonylContact O-C 3.59Å; K262-F265 WeakPolarHBondContact O-CA 3.37Å; K262-F265 PolarHBondContact O-N 3.05Å; K262-F265 VanDerWaalsContact O-N 3.11Å
263Y98.8Very high96.5Very high4 Ų459.5 Ų59.52%0.01634%0.342CS..SBendtrans-109.6126.5168.7-173.2-75.5000110.3H33 L248 T250 V278 Y289 L290 G305 P307H33-Y263 AromaticContact NE2-CE2 3.79Å; H33-Y263 AromaticContact NE2-CZ 3.71Å; H33-Y263 PolarHBondContact NE2-OH 3.49Å; L248-Y263 HydrophobicContact CB-CD2 3.97Å; L248-Y263 HydrophobicContact CB-CG 4.44Å; T250-Y263 PolarHBondContact OG1-N 3.24Å; T250-Y263 PolarHBondContact OG1-O 3.29Å; Y263-V278 HydrophobicContact CD1-CG1 4.43Å; Y263-V278 HydrophobicContact CD2-CB 4.34Å; Y263-V278 HydrophobicContact CD2-CG1 4.02Å; Y263-V278 HydrophobicContact CE1-CG1 3.98Å; Y263-V278 HydrophobicContact CE2-CB 3.65Å; Y263-V278 HydrophobicContact CE2-CG1 3.54Å; Y263-V278 HydrophobicContact CG-CG1 4.46Å; Y263-Y289 WeakPolarHBondContact CE1-O 3.48Å; Y263-Y289 VanDerWaalsContact OH-C 3.26Å; Y263-Y289 PolarHBondContact OH-N 3.26Å; Y263-Y289 PolarHBondContact OH-O 3.23Å; Y263-L290 HydrophobicContact CE1-CB 4.1Å; Y263-L290 HydrophobicContact CE1-CD1 3.89Å; Y263-G305 VanDerWaalsContact CD1-C 3.44Å; Y263-G305 WeakPolarHBondContact CD1-O 3.33Å; Y263-P307 HydrophobicContact CD2-CG 3.71Å; Y263-P307 HydrophobicContact CE2-CG 3.82Å; Y263-P307 HydrophobicContact CG-CG 4.41Å
264P98.8Very high96.6Very high12 Ų1262.9 Ų62.98%0.07835%0.351CS..SBendcis-65.9157.8-16.530.7-35.6000111.5K262 I266 P276 V278 L290 S303K262-P264 CarbonylContact C-O 3.58Å; K262-P264 CarbonylContact O-C 3.59Å; P264-I266 HydrophobicContact CB-CD1 4.38Å; P264-I266 HydrophobicContact CG-CD1 3.85Å; P264-P276 HydrophobicContact CB-CB 3.53Å; P264-P276 HydrophobicContact CG-CB 3.85Å; P264-V278 HydrophobicContact CB-CG1 3.66Å; P264-L290 HydrophobicContact CB-CD1 3.99Å; P264-L290 HydrophobicContact CG-CD1 3.83Å; P264-S303 WeakPolarHBondContact CG-OG 3.34Å
265F98.8Very high96.6Very high66 Ų6660.1 Ų60.129%0.28933%0.334SS..EExtended strand (participates in β ladder)trans-83.7120.4169.4-173.9-85.7000108.6F223 K227 L248 K262 V267 V277F223-F265 HydrophobicContact CE2-CB 4.05Å; F223-F265 HydrophobicContact CE2-CD1 4.48Å; F223-F265 HydrophobicContact CE2-CG 4.23Å; F223-F265 HydrophobicContact CZ-CB 3.88Å; F223-F265 HydrophobicContact CZ-CD1 4.01Å; F223-F265 AromaticContact CZ-CD2 3.86Å; F223-F265 HydrophobicContact CZ-CD2 3.86Å; F223-F265 HydrophobicContact CZ-CE2 4.39Å; F223-F265 AromaticContact CZ-CG 3.64Å; F223-F265 HydrophobicContact CZ-CG 3.64Å; K227-F265 HydrophobicContact CD-CD1 4.12Å; K227-F265 HydrophobicContact CD-CE1 3.66Å; K227-F265 HydrophobicContact CD-CZ 4.16Å; K227-F265 HydrophobicContact CG-CD1 4.22Å; K227-F265 HydrophobicContact CG-CE1 4.13Å; L248-F265 HydrophobicContact CD1-CB 4.02Å; K262-F265 WeakPolarHBondContact O-CA 3.37Å; K262-F265 PolarHBondContact O-N 3.05Å; K262-F265 VanDerWaalsContact O-N 3.11Å; F265-V267 HydrophobicContact CD1-CG2 3.92Å; F265-V267 HydrophobicContact CE1-CG2 3.99Å; F265-V277 HydrophobicContact CB-CB 4.45Å; F265-V277 PolarHBondContact N-O 3.25Å; F265-V277 PolarHBondContact O-N 2.95Å
266I98.7Very high96.7Very high76 Ų7659.1 Ų59.139%0.3933%0.326SS..EExtended strand (participates in β ladder)trans-91.3115.5-174.4-56.7-57.5000110.4P264 K274 P276P264-I266 HydrophobicContact CB-CD1 4.38Å; P264-I266 HydrophobicContact CG-CD1 3.85Å; I266-K274 HydrophobicContact CG2-CB 3.82Å; I266-K274 HydrophobicContact CG2-CD 3.78Å; I266-K274 HydrophobicContact CG2-CG 4.24Å; I266-P276 HydrophobicContact CD1-CB 4.16Å
267V98.8Very high97.1Very high14 Ų1452 Ų529%0.08530%0.296CS..EExtended strand (participates in β ladder)trans-94.2138.6169.6177.50000109.1K227 A230 Q231 F265 K274 V275 V277K227-V267 HydrophobicContact CB-CG2 4.1Å; K227-V267 HydrophobicContact CG-CG2 3.92Å; A230-V267 HydrophobicContact CB-CB 3.86Å; A230-V267 HydrophobicContact CB-CG1 4.02Å; A230-V267 HydrophobicContact CB-CG2 4.05Å; Q231-V267 HydrophobicContact CB-CG1 3.88Å; F265-V267 HydrophobicContact CD1-CG2 3.92Å; F265-V267 HydrophobicContact CE1-CG2 3.99Å; V267-K274 WeakPolarHBondContact O-CA 3.34Å; V267-V275 PolarHBondContact N-O 3.4Å; V267-V275 PolarHBondContact O-N 3.07Å; V267-V277 HydrophobicContact CB-CG2 4.42Å; V267-V277 HydrophobicContact CG2-CG2 3.67Å
268T98.7Very high97.5Very high71 Ų7151.3 Ų51.344%0.43629%0.292SS..EExtended strand (participates in β ladder)trans-91.8115.7167.1-520000107.4R273 K274T268-R273 WeakPolarHBondContact CA-O 3.37Å; T268-K274 PolarHBondContact OG1-NZ 3.05Å
269S98.3Very high97.8Very high7 Ų745.3 Ų45.35%0.04926%0.256CS..  trans-75161.1-179.651.20000112.1A230 Q231 D271 G272 R273A230-S269 WeakPolarHBondContact O-CB 3.08Å; Q231-S269 WeakPolarHBondContact O-CA 3.49Å; S269-D271 VanDerWaalsContact CB-OD1 3.23Å; S269-D271 WeakPolarHBondContact CB-OD1 3.43Å; S269-D271 PolarHBondContact O-N 2.93Å; S269-D271 PolarHBondContact OG-OD1 3.49Å; S269-G272 WeakPolarHBondContact O-CA 3.37Å; S269-G272 PolarHBondContact O-N 3.29Å; S269-R273 PolarHBondContact N-O 3.22Å; S269-R273 WeakPolarHBondContact OG-CA 3.15Å; S269-R273 WeakPolarHBondContact OG-CB 3.36Å; S269-R273 PolarHBondContact OG-N 2.51Å; S269-R273 VanDerWaalsContact OG-N 3.09Å; S269-R273 PolarHBondContact OG-O 3Å; S269-R273 VanDerWaalsContact OG-O 3.14Å
270D98.1Very high97.9Very high113 Ų11343.5 Ų43.560%0.60424%0.244SC*.THydrogen-bonded Turntrans-63.4-22179.9-69.7-13.7000112Q231 G272Q231-D270 WeakPolarHBondContact CG-OD1 3.35Å; Q231-D270 PolarHBondContact NE2-OD1 3.48Å; Q231-D270 PolarHBondContact O-N 3.32Å; D270-G272 VanDerWaalsContact C-N 3.31Å
271D95.5Very high98.2Very high71 Ų7140.8 Ų40.838%0.3822%0.219SC..THydrogen-bonded Turntrans-87.36.8171.968.2-0.1000113.9S269 R273S269-D271 VanDerWaalsContact CB-OD1 3.23Å; S269-D271 WeakPolarHBondContact CB-OD1 3.43Å; S269-D271 PolarHBondContact O-N 2.93Å; S269-D271 PolarHBondContact OG-OD1 3.49Å; D271-R273 IonicContact OD1-CZ 3.71Å; D271-R273 PolarHBondContact OD1-N 3.2Å; D271-R273 IonicContact OD1-NE 3.39Å; D271-R273 PolarHBondContact OD1-NE 2.59Å; D271-R273 IonicContact OD1-NH2 3.14Å; D271-R273 IonicContact OD2-CZ 2.77Å; D271-R273 IonicContact OD2-NE 3.52Å; D271-R273 PolarHBondContact OD2-NE 3.21Å; D271-R273 IonicContact OD2-NH2 3.69Å; D271-R273 PolarHBondContact OD2-NH2 2.75Å
272G97.4Very high97.9Very high55 Ų5539.8 Ų39.857%0.56721%0.208SC*.SBendtrans85.33.1171.600000116S269 D270S269-G272 WeakPolarHBondContact O-CA 3.37Å; S269-G272 PolarHBondContact O-N 3.29Å; D270-G272 VanDerWaalsContact C-N 3.31Å
273R97.4Very high97.7Very high52 Ų5233.6 Ų33.620%0.19618%0.182CC..  trans-80.5164.7177.4-61.1-179.5-65.1110.216111.8V236 D237 T268 S269 D271V236-R273 PolarHBondContact O-NH1 3.03Å; V236-R273 PolarHBondContact O-NH2 2.86Å; D237-R273 IonicContact OD1-NH1 3.8Å; D237-R273 PolarHBondContact OD1-NH1 3.37Å; D237-R273 VanDerWaalsContact OD1-NH1 3.08Å; T268-R273 WeakPolarHBondContact CA-O 3.37Å; S269-R273 PolarHBondContact N-O 3.22Å; S269-R273 WeakPolarHBondContact OG-CA 3.15Å; S269-R273 WeakPolarHBondContact OG-CB 3.36Å; S269-R273 PolarHBondContact OG-N 2.51Å; S269-R273 VanDerWaalsContact OG-N 3.09Å; S269-R273 PolarHBondContact OG-O 3Å; S269-R273 VanDerWaalsContact OG-O 3.14Å; D271-R273 IonicContact OD1-CZ 3.71Å; D271-R273 PolarHBondContact OD1-N 3.2Å; D271-R273 IonicContact OD1-NE 3.39Å; D271-R273 PolarHBondContact OD1-NE 2.59Å; D271-R273 IonicContact OD1-NH2 3.14Å; D271-R273 IonicContact OD2-CZ 2.77Å; D271-R273 IonicContact OD2-NE 3.52Å; D271-R273 PolarHBondContact OD2-NE 3.21Å; D271-R273 IonicContact OD2-NH2 3.69Å; D271-R273 PolarHBondContact OD2-NH2 2.75Å
274K98.4Very high97.7Very high124 Ų12433.8 Ų33.854%0.53918%0.184SC..EExtended strand (participates in β ladder)trans-103.3108.9172.7-62.3-61-179.8179.90108.3I266 V267 T268I266-K274 HydrophobicContact CG2-CB 3.82Å; I266-K274 HydrophobicContact CG2-CD 3.78Å; I266-K274 HydrophobicContact CG2-CG 4.24Å; V267-K274 WeakPolarHBondContact O-CA 3.34Å; T268-K274 PolarHBondContact OG1-NZ 3.05Å
275V98.9Very high97.6Very high0 Ų033.2 Ų33.20%018%0.181CC..EExtended strand (participates in β ladder)trans-105.3114-176.1-178.40000109A230 V239 V267A230-V275 HydrophobicContact CB-CB 4.05Å; A230-V275 HydrophobicContact CB-CG1 3.69Å; V239-V275 HydrophobicContact CG2-CG1 4.31Å; V267-V275 PolarHBondContact N-O 3.4Å; V267-V275 PolarHBondContact O-N 3.07Å
276P98.9Very high97.6Very high0 Ų030.2 Ų30.20%017%0.167CC..EExtended strand (participates in β ladder)trans-68.2130.5172.625.9-34.6000111.9D237 V238 V239 P264 I266 L290D237-P276 WeakPolarHBondContact O-CD 3.47Å; V238-P276 HydrophobicContact CG1-CG 4.22Å; V238-P276 HydrophobicContact CG2-CG 4.24Å; V239-P276 PolarHBondContact N-O 3.16Å; P264-P276 HydrophobicContact CB-CB 3.53Å; P264-P276 HydrophobicContact CG-CB 3.85Å; I266-P276 HydrophobicContact CD1-CB 4.16Å; P276-L290 HydrophobicContact CB-CD2 4.39Å
277V98.9Very high97.6Very high0 Ų026.6 Ų26.60%015%0.149CC..EExtended strand (participates in β ladder)trans-112131.1171.2-175.90000109F223 D226 A230 V239 F265 V267F223-V277 HydrophobicContact CD2-CG1 4.03Å; F223-V277 HydrophobicContact CE2-CB 4.43Å; F223-V277 HydrophobicContact CE2-CG1 3.83Å; D226-V277 HydrophobicContact CB-CG1 3.71Å; A230-V277 HydrophobicContact CB-CG2 3.55Å; V239-V277 HydrophobicContact CB-CG1 4.34Å; V239-V277 HydrophobicContact CB-CG2 4.19Å; V239-V277 HydrophobicContact CG2-CG2 4.5Å; V239-V277 WeakPolarHBondContact O-CA 3.06Å; F265-V277 HydrophobicContact CB-CB 4.45Å; F265-V277 PolarHBondContact N-O 3.25Å; F265-V277 PolarHBondContact O-N 2.95Å; V267-V277 HydrophobicContact CB-CG2 4.42Å; V267-V277 HydrophobicContact CG2-CG2 3.67Å
278V98.9Very high97.6Very high0 Ų025.9 Ų25.90%015%0.145CC..EExtended strand (participates in β ladder)trans-134.6145.1-178.9-66.10000112.7H33 V239 V240 G241 Y263 P264 L290H33-V278 WeakPolarHBondContact NE2-CG2 3.39Å; V239-V278 PolarHBondContact O-N 2.82Å; V240-V278 HydrophobicContact CB-CG2 4.17Å; V240-V278 HydrophobicContact CG1-CG2 4.29Å; V240-V278 HydrophobicContact CG2-CG2 3.67Å; G241-V278 PolarHBondContact N-O 2.82Å; Y263-V278 HydrophobicContact CD1-CG1 4.43Å; Y263-V278 HydrophobicContact CD2-CB 4.34Å; Y263-V278 HydrophobicContact CD2-CG1 4.02Å; Y263-V278 HydrophobicContact CE1-CG1 3.98Å; Y263-V278 HydrophobicContact CE2-CB 3.65Å; Y263-V278 HydrophobicContact CE2-CG1 3.54Å; Y263-V278 HydrophobicContact CG-CG1 4.46Å; P264-V278 HydrophobicContact CB-CG1 3.66Å; V278-L290 HydrophobicContact CG1-CD1 4.37Å; V278-L290 HydrophobicContact CG1-CD2 3.87Å; V278-L290 HydrophobicContact CG2-CD2 4.35Å
279Q98.6Very high97.7Very high0 Ų024.7 Ų24.70%013%0.132CC..  trans-139.9161.7163.7-65.8-157.5-7.900108.2D226 G241 G242 S244 T246D226-Q279 PolarHBondContact OD2-NE2 2.79Å; G241-Q279 WeakPolarHBondContact O-CG 3.2Å; G242-Q279 PolarHBondContact O-NE2 2.98Å; S244-Q279 PolarHBondContact OG-NE2 3.36Å; S244-Q279 PolarHBondContact OG-OE1 3.39Å; T246-Q279 VanDerWaalsContact O-CB 3.31Å; T246-Q279 WeakPolarHBondContact O-CB 3.35Å; T246-Q279 PolarHBondContact OG1-OE1 3.32Å
280A98.3Very high97.7Very high2 Ų224.3 Ų24.32%0.01713%0.13CC..BIsolated β-bridgetrans-12542.8-174.200000113.1N35 A282N35-A280 WeakPolarHBondContact OD1-CA 3.25Å; N35-A280 WeakPolarHBondContact OD1-CB 3.47Å; N35-A280 PolarHBondContact OD1-N 3.33Å; A280-A282 PolarHBondContact O-N 3.25Å
281Y97.2Very high97.7Very high17 Ų1720.1 Ų20.17%0.06711%0.106CC..  trans60.8-113.5-176.6-179.6-119.4000111.2N35 N245 T246 F247 E257 F283 K285 Y286N35-Y281 PolarHBondContact ND2-O 2.92Å; N245-Y281 CarbonylContact C-O 2.86Å; N245-Y281 VanDerWaalsContact CA-O 3.24Å; N245-Y281 WeakPolarHBondContact CA-O 3.5Å; N245-Y281 WeakPolarHBondContact O-CD2 3.27Å; T246-Y281 PolarHBondContact O-N 3.35Å; F247-Y281 HydrophobicContact CB-CD2 4.09Å; F247-Y281 HydrophobicContact CB-CG 4.43Å; E257-Y281 HydrophobicContact CG-CD1 4.02Å; E257-Y281 HydrophobicContact CG-CD2 3.82Å; E257-Y281 HydrophobicContact CG-CE1 3.79Å; E257-Y281 HydrophobicContact CG-CE2 3.59Å; E257-Y281 HydrophobicContact CG-CG 4.02Å; Y281-F283 AromaticContact CE1-CD2 3.99Å; Y281-F283 HydrophobicContact CE1-CD2 3.99Å; Y281-F283 HydrophobicContact CE1-CE2 4.49Å; Y281-K285 HydrophobicContact CD1-CB 4.41Å; Y281-K285 HydrophobicContact CD1-CD 4.43Å; Y281-K285 HydrophobicContact CE1-CD 4.2Å; Y281-Y286 HydrophobicContact CD1-CD2 4.02Å; Y281-Y286 HydrophobicContact CD1-CE2 4.07Å; Y281-Y286 HydrophobicContact CG-CD2 4.42Å
282A90.9Very high97.9Very high1 Ų116.8 Ų16.81%0.0089%0.088CC..SBendtrans-167.7-179.8-177.400000111.2D36 N245 A280 G284 K285D36-A282 HydrophobicContact CB-CB 3.85Å; N245-A282 HydrophobicContact CB-CB 4.04Å; A280-A282 PolarHBondContact O-N 3.25Å; A282-G284 PolarHBondContact O-N 3.14Å; A282-G284 VanDerWaalsContact O-N 3.1Å; A282-K285 PolarHBondContact O-N 3Å
283F94.1Very high97.9Very high21 Ų2117.2 Ų17.29%0.0928%0.076CC..THydrogen-bonded Turntrans64.616164.8-51-52.7000115.2D36 V37 H38 R40 S48 Y281 K285D36-F283 PolarHBondContact O-N 3.19Å; V37-F283 WeakPolarHBondContact O-CA 3.44Å; H38-F283 HydrophobicContact CB-CD1 4.13Å; H38-F283 HydrophobicContact CB-CE1 4.23Å; H38-F283 AromaticContact CD2-CE1 3.7Å; R40-F283 WeakPolarHBondContact CB-O 3.47Å; R40-F283 HydrophobicContact CG-CB 3.97Å; R40-F283 HydrophobicContact CG-CD1 4.37Å; S48-F283 WeakPolarHBondContact OG-CB 3.36Å; S48-F283 WeakPolarHBondContact OG-CD2 3.48Å; Y281-F283 AromaticContact CE1-CD2 3.99Å; Y281-F283 HydrophobicContact CE1-CD2 3.99Å; Y281-F283 HydrophobicContact CE1-CE2 4.49Å; F283-K285 PolarHBondContact O-N 2.69Å; F283-K285 VanDerWaalsContact O-N 3.13Å
284G97.2Very high97.9Very high7 Ų714.9 Ų14.97%0.0727%0.067CC..THydrogen-bonded Turntrans60.419.4-173.900000113.4G59 A282 Y286G59-G284 WeakPolarHBondContact CA-O 3.35Å; A282-G284 PolarHBondContact O-N 3.14Å; A282-G284 VanDerWaalsContact O-N 3.1Å; G284-Y286 VanDerWaalsContact C-N 3.3Å
285K98.1Very high97.9Very high0 Ų010.7 Ų10.70%05%0.05CC..SBendtrans-70.4-31177.6-179.8174.2173.9173.20111.7E46 M58 S255 E257 Y281 A282 F283 L309 L310E46-K285 PolarHBondContact O-NZ 2.94Å; M58-K285 HydrophobicContact CB-CG 4.44Å; M58-K285 HydrophobicContact SD-CD 4.38Å; M58-K285 VanDerWaalsContact SD-CE 3.56Å; M58-K285 HydrophobicContact SD-CG 4.39Å; S255-K285 PolarHBondContact OG-NZ 2.65Å; E257-K285 IonicContact OE1-NZ 3.45Å; E257-K285 PolarHBondContact OE1-NZ 2.8Å; E257-K285 WeakPolarHBondContact OE2-CE 3.46Å; E257-K285 IonicContact OE2-NZ 2.74Å; E257-K285 PolarHBondContact OE2-NZ 3.22Å; Y281-K285 HydrophobicContact CD1-CB 4.41Å; Y281-K285 HydrophobicContact CD1-CD 4.43Å; Y281-K285 HydrophobicContact CE1-CD 4.2Å; A282-K285 PolarHBondContact O-N 3Å; F283-K285 PolarHBondContact O-N 2.69Å; F283-K285 VanDerWaalsContact O-N 3.13Å; K285-L309 HydrophobicContact CG-CD1 3.96Å; K285-L310 WeakPolarHBondContact O-CB 3.49Å; K285-L310 PolarHBondContact O-N 3.32Å
286Y98.9Very high97.7Very high3 Ų317.3 Ų17.31%0.0128%0.081CC..EExtended strand (participates in β ladder)trans-122.5149.1178.5-64.6-93.4000111.1F247 P254 S255 E257 Y281 G284 P307 I308 L309F247-Y286 HydrophobicContact CD2-CE2 4.42Å; F247-Y286 HydrophobicContact CE2-CD1 4.16Å; F247-Y286 HydrophobicContact CE2-CD2 4.42Å; F247-Y286 AromaticContact CE2-CE1 3.78Å; F247-Y286 HydrophobicContact CE2-CE1 3.78Å; F247-Y286 HydrophobicContact CE2-CE2 4.08Å; F247-Y286 HydrophobicContact CE2-CG 4.46Å; F247-Y286 AromaticContact CE2-CZ 3.75Å; F247-Y286 HydrophobicContact CZ-CE1 4.13Å; P254-Y286 HydrophobicContact CG-CE1 3.84Å; S255-Y286 WeakPolarHBondContact CB-OH 3.27Å; E257-Y286 HydrophobicContact CG-CE2 4.5Å; E257-Y286 PolarHBondContact OE2-OH 2.94Å; E257-Y286 VanDerWaalsContact OE2-OH 3.08Å; Y281-Y286 HydrophobicContact CD1-CD2 4.02Å; Y281-Y286 HydrophobicContact CD1-CE2 4.07Å; Y281-Y286 HydrophobicContact CG-CD2 4.42Å; G284-Y286 VanDerWaalsContact C-N 3.3Å; Y286-P307 HydrophobicContact CD1-CB 3.86Å; Y286-P307 HydrophobicContact CG-CB 4.14Å; Y286-I308 VanDerWaalsContact CA-O 3.29Å; Y286-I308 WeakPolarHBondContact CA-O 3.44Å; Y286-L309 HydrophobicContact CD1-CB 4.11Å; Y286-L309 HydrophobicContact CD1-CD1 4.3Å; Y286-L309 HydrophobicContact CE1-CB 3.77Å; Y286-L309 HydrophobicContact CE1-CD1 3.76Å; Y286-L309 HydrophobicContact CE1-CG 4.35Å; Y286-L309 HydrophobicContact CE2-CD1 4.29Å
287L98.9Very high97.5Very high0 Ų026.1 Ų26.10%012%0.115CC..EExtended strand (participates in β ladder)trans-103.6115.1161.617458.7000108.1L32 T34 L64 K67 V68 I71 L80 Y289 P307 I308 L310L32-L287 HydrophobicContact CB-CD1 4.12Å; L32-L287 HydrophobicContact CD1-CD2 4.48Å; L32-L287 HydrophobicContact CD2-CD2 4.24Å; L32-L287 HydrophobicContact CD2-CG 4.46Å; T34-L287 HydrophobicContact CG2-CD1 4.26Å; L64-L287 HydrophobicContact CD1-CB 4.02Å; L64-L287 HydrophobicContact CD1-CD1 3.7Å; L64-L287 HydrophobicContact CD1-CD2 4.03Å; L64-L287 HydrophobicContact CD1-CG 4.12Å; K67-L287 HydrophobicContact CB-CD2 4.29Å; K67-L287 HydrophobicContact CG-CD2 3.77Å; V68-L287 HydrophobicContact CG2-CD1 4.5Å; V68-L287 HydrophobicContact CG2-CD2 3.91Å; I71-L287 HydrophobicContact CD1-CD2 4.11Å; L80-L287 HydrophobicContact CD1-CD1 4.24Å; L287-Y289 PolarHBondContact O-N 2.89Å; L287-P307 CarbonylContact O-C 3.59Å; L287-P307 WeakPolarHBondContact O-CA 3.41Å; L287-I308 HydrophobicContact CB-CB 4.48Å; L287-I308 PolarHBondContact N-O 2.91Å; L287-I308 PolarHBondContact O-N 2.88Å; L287-L310 HydrophobicContact CB-CD1 4.34Å; L287-L310 HydrophobicContact CB-CD2 4.18Å; L287-L310 HydrophobicContact CB-CG 4.41Å
288G98.9Very high97.4Very high0 Ų026.2 Ų26.20%012%0.115CC..EExtended strand (participates in β ladder)trans-58134.2170.100000110.8L32 H33L32-G288 VanDerWaalsContact CA-O 3.28Å; L32-G288 WeakPolarHBondContact CA-O 3.31Å; H33-G288 PolarHBondContact N-O 3.44Å; H33-G288 WeakPolarHBondContact NE2-CA 3.46Å; H33-G288 WeakPolarHBondContact O-CA 3.48Å; H33-G288 PolarHBondContact O-N 3.15Å
289Y98.9Very high97.2Very high45 Ų4528.9 Ų28.918%0.17613%0.13CC..EExtended strand (participates in β ladder)trans-138.6110.9179.1172.7-92.5000108.9T30 L32 I71 E75 Y263 L287 K291 G305 N306 I308T30-Y289 HydrophobicContact CG2-CD2 3.83Å; T30-Y289 HydrophobicContact CG2-CE2 3.52Å; L32-Y289 HydrophobicContact CD2-CD2 3.66Å; I71-Y289 HydrophobicContact CD1-CD2 3.96Å; I71-Y289 HydrophobicContact CD1-CE2 4.32Å; I71-Y289 HydrophobicContact CG2-CD2 4.47Å; I71-Y289 HydrophobicContact CG2-CE2 4.04Å; E75-Y289 PolarHBondContact OE1-OH 3.43Å; Y263-Y289 WeakPolarHBondContact CE1-O 3.48Å; Y263-Y289 VanDerWaalsContact OH-C 3.26Å; Y263-Y289 PolarHBondContact OH-N 3.26Å; Y263-Y289 PolarHBondContact OH-O 3.23Å; L287-Y289 PolarHBondContact O-N 2.89Å; Y289-K291 HydrophobicContact CE1-CD 4.28Å; Y289-K291 HydrophobicContact CE1-CG 3.74Å; Y289-K291 VanDerWaalsContact OH-CD 3.24Å; Y289-K291 WeakPolarHBondContact OH-CD 3.31Å; Y289-K291 WeakPolarHBondContact OH-CG 3.47Å; Y289-G305 WeakPolarHBondContact O-CA 3.45Å; Y289-N306 PolarHBondContact O-N 3.08Å; Y289-N306 VanDerWaalsContact O-N 3.15Å; Y289-I308 HydrophobicContact CD2-CD1 4.3Å; Y289-I308 HydrophobicContact CG-CD1 4.12Å
290L98.9Very high97.2Very high0 Ų030.7 Ų30.70%014%0.14CC..EExtended strand (participates in β ladder)trans-126.8121.9178-17767.2000109.3T30 I31 V238 Y263 P264 P276 V278 I292T30-L290 WeakPolarHBondContact CA-O 3.45Å; I31-L290 HydrophobicContact CB-CB 4.45Å; I31-L290 PolarHBondContact N-O 2.83Å; I31-L290 PolarHBondContact O-N 3.13Å; V238-L290 HydrophobicContact CG1-CD2 4.07Å; Y263-L290 HydrophobicContact CE1-CB 4.1Å; Y263-L290 HydrophobicContact CE1-CD1 3.89Å; P264-L290 HydrophobicContact CB-CD1 3.99Å; P264-L290 HydrophobicContact CG-CD1 3.83Å; P276-L290 HydrophobicContact CB-CD2 4.39Å; V278-L290 HydrophobicContact CG1-CD1 4.37Å; V278-L290 HydrophobicContact CG1-CD2 3.87Å; V278-L290 HydrophobicContact CG2-CD2 4.35Å; L290-I292 HydrophobicContact CD2-CD1 3.62Å; L290-I292 HydrophobicContact CD2-CG1 3.88Å; L290-I292 HydrophobicContact CG-CD1 4.1Å; L290-I292 HydrophobicContact CG-CG1 3.78Å
291K98.8Very high97.2Very high25 Ų2535.5 Ų35.511%0.10917%0.165CC..EExtended strand (participates in β ladder)trans-92.5136.5166.4-55.4-159.784.3175.50109.2E28 L29 E75 Y289 S303 H304E28-K291 VanDerWaalsContact OE1-CE 3.22Å; E28-K291 WeakPolarHBondContact OE1-CE 3.47Å; E28-K291 IonicContact OE1-NZ 3.84Å; E28-K291 PolarHBondContact OE1-NZ 3.27Å; E28-K291 WeakPolarHBondContact OE2-CE 3.23Å; E28-K291 IonicContact OE2-NZ 3.86Å; E28-K291 PolarHBondContact OE2-NZ 3.17Å; L29-K291 WeakPolarHBondContact O-CA 3.43Å; E75-K291 IonicContact OE1-NZ 2.97Å; E75-K291 PolarHBondContact OE1-NZ 2.82Å; E75-K291 IonicContact OE2-NZ 2.84Å; E75-K291 PolarHBondContact OE2-NZ 3.16Å; Y289-K291 HydrophobicContact CE1-CD 4.28Å; Y289-K291 HydrophobicContact CE1-CG 3.74Å; Y289-K291 VanDerWaalsContact OH-CD 3.24Å; Y289-K291 WeakPolarHBondContact OH-CD 3.31Å; Y289-K291 WeakPolarHBondContact OH-CG 3.47Å; K291-S303 CarbonylContact O-C 3.49Å; K291-S303 VanDerWaalsContact O-CA 3.29Å; K291-S303 WeakPolarHBondContact O-CA 2.89Å; K291-H304 PolarHBondContact N-O 3.41Å; K291-H304 PolarHBondContact O-N 2.87Å
292I98.4Very high97.2Very high0 Ų036.5 Ų36.50%017%0.174CC..EExtended strand (participates in β ladder)trans-133.3131.1180-51.1-174.4000108.9E28 L29 I31 V238 L290 F294 V300E28-I292 CarbonylContact C-O 3.17Å; E28-I292 WeakPolarHBondContact CA-O 3.37Å; L29-I292 PolarHBondContact N-O 3.24Å; L29-I292 PolarHBondContact O-N 2.93Å; I31-I292 HydrophobicContact CD1-CD1 3.59Å; I31-I292 HydrophobicContact CG1-CD1 4.44Å; V238-I292 HydrophobicContact CB-CD1 4.23Å; V238-I292 HydrophobicContact CG1-CD1 3.97Å; V238-I292 HydrophobicContact CG2-CD1 3.21Å; L290-I292 HydrophobicContact CD2-CD1 3.62Å; L290-I292 HydrophobicContact CD2-CG1 3.88Å; L290-I292 HydrophobicContact CG-CD1 4.1Å; L290-I292 HydrophobicContact CG-CG1 3.78Å; I292-F294 HydrophobicContact CB-CD2 4.45Å; I292-F294 HydrophobicContact CB-CE2 3.92Å; I292-F294 HydrophobicContact CB-CZ 4.48Å; I292-F294 HydrophobicContact CG2-CD2 3.91Å; I292-F294 HydrophobicContact CG2-CE1 4.27Å; I292-F294 HydrophobicContact CG2-CE2 3.45Å; I292-F294 VanDerWaalsContact CG2-CE2 3.45Å; I292-F294 HydrophobicContact CG2-CG 4.5Å; I292-F294 HydrophobicContact CG2-CZ 3.67Å; I292-V300 HydrophobicContact CG2-CB 4.46Å; I292-V300 HydrophobicContact CG2-CG1 3.86Å; I292-V300 HydrophobicContact CG2-CG2 4Å
293E98.4Very high97.6Very high65 Ų6537.7 Ų37.730%0.30418%0.183SC..EExtended strand (participates in β ladder)trans-103.1125.4172.9-65.5176.3161.700109.4E28 I301 S302E28-E293 HydrophobicContact CG-CG 4.45Å; E293-I301 HydrophobicContact CB-CB 4.36Å; E293-I301 PolarHBondContact O-N 3.1Å; E293-S302 PolarHBondContact N-O 2.92Å; E293-S302 PolarHBondContact OE2-OG 3.21Å
294F98.3Very high97.8Very high2 Ų241.2 Ų41.21%0.00920%0.199CC..EExtended strand (participates in β ladder)trans-108.6144.4177.4-70.8-82.4000111.6A26 W27 L29 K214 D237 V238 I292 G298 N299 V300A26-F294 WeakPolarHBondContact CA-O 3.38Å; W27-F294 HydrophobicContact CE3-CB 4.43Å; W27-F294 AromaticContact CE3-CD2 3.83Å; W27-F294 HydrophobicContact CE3-CD2 3.83Å; W27-F294 HydrophobicContact CE3-CG 4.49Å; W27-F294 HydrophobicContact CZ3-CD2 4Å; W27-F294 HydrophobicContact CZ3-CE2 4.35Å; W27-F294 PolarHBondContact N-O 2.91Å; W27-F294 PolarHBondContact O-N 3.47Å; L29-F294 HydrophobicContact CB-CE2 4.28Å; L29-F294 HydrophobicContact CD2-CE2 4.29Å; K214-F294 HydrophobicContact CB-CE1 4.46Å; K214-F294 HydrophobicContact CD-CB 3.96Å; K214-F294 HydrophobicContact CD-CD1 4.07Å; K214-F294 HydrophobicContact CD-CD2 3.83Å; K214-F294 HydrophobicContact CD-CE1 4.48Å; K214-F294 HydrophobicContact CD-CE2 4.28Å; K214-F294 HydrophobicContact CD-CG 3.69Å; K214-F294 HydrophobicContact CG-CB 4.48Å; K214-F294 HydrophobicContact CG-CD1 3.78Å; K214-F294 HydrophobicContact CG-CD2 4.33Å; K214-F294 HydrophobicContact CG-CE1 3.94Å; K214-F294 HydrophobicContact CG-CE2 4.49Å; K214-F294 HydrophobicContact CG-CG 3.96Å; K214-F294 HydrophobicContact CG-CZ 4.3Å; D237-F294 HydrophobicContact CB-CE1 3.86Å; D237-F294 HydrophobicContact CB-CZ 4.33Å; V238-F294 HydrophobicContact CG2-CZ 4.37Å; I292-F294 HydrophobicContact CB-CD2 4.45Å; I292-F294 HydrophobicContact CB-CE2 3.92Å; I292-F294 HydrophobicContact CB-CZ 4.48Å; I292-F294 HydrophobicContact CG2-CD2 3.91Å; I292-F294 HydrophobicContact CG2-CE1 4.27Å; I292-F294 HydrophobicContact CG2-CE2 3.45Å; I292-F294 VanDerWaalsContact CG2-CE2 3.45Å; I292-F294 HydrophobicContact CG2-CG 4.5Å; I292-F294 HydrophobicContact CG2-CZ 3.67Å; F294-G298 VanDerWaalsContact CD1-O 3.25Å; F294-G298 WeakPolarHBondContact CD1-O 3.43Å; F294-N299 CarbonylContact C-O 3.59Å; F294-N299 VanDerWaalsContact CA-O 3.32Å; F294-N299 WeakPolarHBondContact CA-O 3.41Å; F294-V300 HydrophobicContact CD1-CG2 4.09Å; F294-V300 HydrophobicContact CE1-CG2 3.52Å; F294-V300 HydrophobicContact CZ-CG2 4.1Å
295D96.7Very high97.9Very high36 Ų3641.6 Ų41.619%0.19320%0.203CC..  trans-75.6170.6162.479.83000111.1R297 G298 N299 I301D295-R297 PolarHBondContact O-N 2.97Å; D295-R297 VanDerWaalsContact O-N 3.08Å; D295-R297 VanDerWaalsContact OD1-C 3.27Å; D295-R297 VanDerWaalsContact OD1-CA 3.28Å; D295-R297 WeakPolarHBondContact OD1-CA 3.43Å; D295-R297 WeakPolarHBondContact OD1-CB 3.44Å; D295-R297 PolarHBondContact OD1-N 2.79Å; D295-R297 IonicContact OD2-NE 3.72Å; D295-R297 IonicContact OD2-NH2 3.8Å; D295-G298 PolarHBondContact O-N 3.04Å; D295-G298 PolarHBondContact OD1-N 3.41Å; D295-N299 PolarHBondContact N-O 3.42Å; D295-N299 PolarHBondContact OD1-N 3.03Å; D295-N299 PolarHBondContact OD1-ND2 3.08Å; D295-N299 PolarHBondContact OD2-ND2 3.32Å; D295-I301 HydrophobicContact CB-CD1 3.94Å; D295-I301 HydrophobicContact CB-CG1 4.1Å
296E94.8Very high97.9Very high139 Ų13943.4 Ų43.465%0.6521%0.213SC*.THydrogen-bonded Turntrans-59.5-21.9178.8-64.7-174153.900113.4A24 N213 G298A24-E296 HydrophobicContact CB-CG 3.98Å; A24-E296 WeakPolarHBondContact CB-OE1 3.48Å; N213-E296 PolarHBondContact ND2-O 2.74Å; N213-E296 VanDerWaalsContact ND2-O 3.15Å; E296-G298 VanDerWaalsContact C-N 3.32Å
297R95.3Very high97.9Very high186 Ų18643.3 Ų43.370%0.70221%0.213SC*.THydrogen-bonded Turntrans-89.91.3178.3-62.4-177.5-66-176-1.6112.5N213 D295N213-R297 WeakPolarHBondContact CB-O 3.47Å; D295-R297 PolarHBondContact O-N 2.97Å; D295-R297 VanDerWaalsContact O-N 3.08Å; D295-R297 VanDerWaalsContact OD1-C 3.27Å; D295-R297 VanDerWaalsContact OD1-CA 3.28Å; D295-R297 WeakPolarHBondContact OD1-CA 3.43Å; D295-R297 WeakPolarHBondContact OD1-CB 3.44Å; D295-R297 PolarHBondContact OD1-N 2.79Å; D295-R297 IonicContact OD2-NE 3.72Å; D295-R297 IonicContact OD2-NH2 3.8Å
298G96Very high97.9Very high1 Ų145.4 Ų45.41%0.0122%0.223CC..SBendtrans80.614.8-179.700000114.4F294 D295 E296F294-G298 VanDerWaalsContact CD1-O 3.25Å; F294-G298 WeakPolarHBondContact CD1-O 3.43Å; D295-G298 PolarHBondContact O-N 3.04Å; D295-G298 PolarHBondContact OD1-N 3.41Å; E296-G298 VanDerWaalsContact C-N 3.32Å
299N96.4Very high97.9Very high57 Ų5746.3 Ų46.331%0.30523%0.228SC..  trans-80.8138.5173-55.7-65.9000110.6F294 D295 I301F294-N299 CarbonylContact C-O 3.59Å; F294-N299 VanDerWaalsContact CA-O 3.32Å; F294-N299 WeakPolarHBondContact CA-O 3.41Å; D295-N299 PolarHBondContact N-O 3.42Å; D295-N299 PolarHBondContact OD1-N 3.03Å; D295-N299 PolarHBondContact OD1-ND2 3.08Å; D295-N299 PolarHBondContact OD2-ND2 3.32Å; N299-I301 PolarHBondContact O-N 2.82Å
300V98.1Very high97.9Very high37 Ų3744.2 Ų44.222%0.22422%0.22CC..EExtended strand (participates in β ladder)trans-69117.3173.1179.70000109.9D237 I292 F294D237-V300 HydrophobicContact CB-CG2 3.99Å; I292-V300 HydrophobicContact CG2-CB 4.46Å; I292-V300 HydrophobicContact CG2-CG1 3.86Å; I292-V300 HydrophobicContact CG2-CG2 4Å; F294-V300 HydrophobicContact CD1-CG2 4.09Å; F294-V300 HydrophobicContact CE1-CG2 3.52Å; F294-V300 HydrophobicContact CZ-CG2 4.1Å
301I97.6Very high97.8Very high103 Ų10346.4 Ų46.453%0.52823%0.232SC..EExtended strand (participates in β ladder)trans-83.5-48.8173.3-57.8173.2000109.3A26 E293 D295 N299A26-I301 HydrophobicContact CB-CD1 4.04Å; E293-I301 HydrophobicContact CB-CB 4.36Å; E293-I301 PolarHBondContact O-N 3.1Å; D295-I301 HydrophobicContact CB-CD1 3.94Å; D295-I301 HydrophobicContact CB-CG1 4.1Å; N299-I301 PolarHBondContact O-N 2.82Å
302S98.1Very high97.8Very high38 Ų3848.1 Ų48.127%0.26625%0.247SC..EExtended strand (participates in β ladder)trans-149.1155.1-178.285.50000110.7E293E293-S302 PolarHBondContact N-O 2.92Å; E293-S302 PolarHBondContact OE2-OG 3.21Å
303S98.4Very high97.7Very high26 Ų2652.7 Ų52.718%0.18228%0.279CS..EExtended strand (participates in β ladder)trans-148.8127.3175.5650000109.8P264 K291P264-S303 WeakPolarHBondContact CG-OG 3.34Å; K291-S303 CarbonylContact O-C 3.49Å; K291-S303 VanDerWaalsContact O-CA 3.29Å; K291-S303 WeakPolarHBondContact O-CA 2.89Å
304H98.4Very high97.7Very high95 Ų9550.1 Ų50.144%0.4427%0.267SS..EExtended strand (participates in β ladder)trans-150.3157.8179.669.684.6000111.9K291K291-H304 PolarHBondContact N-O 3.41Å; K291-H304 PolarHBondContact O-N 2.87Å
305G98.6Very high97.7Very high16 Ų1653.8 Ų53.817%0.16529%0.291CS..EExtended strand (participates in β ladder)trans160.1-169.9-179.500000111.9Y263 Y289Y263-G305 VanDerWaalsContact CD1-C 3.44Å; Y263-G305 WeakPolarHBondContact CD1-O 3.33Å; Y289-G305 WeakPolarHBondContact O-CA 3.45Å
306N98.8Very high97.8Very high38 Ų3853.8 Ų53.820%0.20329%0.29CS..  trans-164.1150.4172.1-96.8-43.6000109.2Y249 T250 Y289 I308Y249-N306 HydrophobicContact CD2-CB 4.46Å; Y249-N306 HydrophobicContact CE2-CB 3.95Å; T250-N306 PolarHBondContact N-OD1 2.98Å; T250-N306 PolarHBondContact O-ND2 2.94Å; Y289-N306 PolarHBondContact O-N 3.08Å; Y289-N306 VanDerWaalsContact O-N 3.15Å; N306-I308 PolarHBondContact O-N 2.62Å
307P98.8Very high98Very high0 Ų048.6 Ų48.60%027%0.267CS..PPolyproline II helixtrans-60.2129.5169.2-2032.5000111.1F247 L248 Y249 Y263 Y286 L287F247-P307 HydrophobicContact CE2-CB 4.45Å; F247-P307 HydrophobicContact CE2-CG 4.37Å; L248-P307 WeakPolarHBondContact O-CD 3.24Å; L248-P307 WeakPolarHBondContact O-CG 3.24Å; Y249-P307 WeakPolarHBondContact CE2-O 3.49Å; Y263-P307 HydrophobicContact CD2-CG 3.71Å; Y263-P307 HydrophobicContact CE2-CG 3.82Å; Y263-P307 HydrophobicContact CG-CG 4.41Å; Y286-P307 HydrophobicContact CD1-CB 3.86Å; Y286-P307 HydrophobicContact CG-CB 4.14Å; L287-P307 CarbonylContact O-C 3.59Å; L287-P307 WeakPolarHBondContact O-CA 3.41Å
308I98.9Very high98.2Very high44 Ų4444.5 Ų44.523%0.22626%0.264CS..EExtended strand (participates in β ladder)trans-86.3117-179.8-57.5172.9000108.3K67 I71 Y286 L287 Y289 N306 L310 I314K67-I308 HydrophobicContact CD-CD1 4.19Å; K67-I308 HydrophobicContact CD-CG2 4.33Å; K67-I308 HydrophobicContact CG-CD1 4.29Å; K67-I308 HydrophobicContact CG-CG2 4.33Å; I71-I308 HydrophobicContact CD1-CD1 3.78Å; Y286-I308 VanDerWaalsContact CA-O 3.29Å; Y286-I308 WeakPolarHBondContact CA-O 3.44Å; L287-I308 HydrophobicContact CB-CB 4.48Å; L287-I308 PolarHBondContact N-O 2.91Å; L287-I308 PolarHBondContact O-N 2.88Å; Y289-I308 HydrophobicContact CD2-CD1 4.3Å; Y289-I308 HydrophobicContact CG-CD1 4.12Å; N306-I308 PolarHBondContact O-N 2.62Å; I308-L310 PolarHBondContact O-N 2.87Å; I308-I314 HydrophobicContact CG2-CD1 4.37Å
309L98.8Very high98.3Very high20 Ų2048.8 Ų48.811%0.10529%0.294CS..EExtended strand (participates in β ladder)trans-65119.4173.9178.165.4000110M58 P254 K285 Y286 N311M58-L309 HydrophobicContact SD-CD1 3.88Å; P254-L309 HydrophobicContact CB-CB 4.27Å; P254-L309 HydrophobicContact CB-CD2 4.03Å; P254-L309 HydrophobicContact CG-CB 3.9Å; P254-L309 HydrophobicContact CG-CD2 4.29Å; K285-L309 HydrophobicContact CG-CD1 3.96Å; Y286-L309 HydrophobicContact CD1-CB 4.11Å; Y286-L309 HydrophobicContact CD1-CD1 4.3Å; Y286-L309 HydrophobicContact CE1-CB 3.77Å; Y286-L309 HydrophobicContact CE1-CD1 3.76Å; Y286-L309 HydrophobicContact CE1-CG 4.35Å; Y286-L309 HydrophobicContact CE2-CD1 4.29Å; L309-N311 VanDerWaalsContact C-N 3.26Å; L309-N311 HydrophobicContact CD2-CB 4.08Å; L309-N311 HydrophobicContact CG-CB 4.05Å; L309-N311 PolarHBondContact O-N 2.75Å
310L98.8Very high98.4Very high0 Ų046.7 Ų46.70%028%0.283CS..  trans-84.565.3178.3-61.1-178.9000110.5M58 G59 R63 L64 K67 K285 L287 I308 I314M58-L310 CarbonylContact C-O 3.57Å; M58-L310 WeakPolarHBondContact CA-O 3.31Å; G59-L310 PolarHBondContact N-O 3.26Å; R63-L310 VanDerWaalsContact CD-C 3.48Å; R63-L310 WeakPolarHBondContact CD-O 3.44Å; R63-L310 HydrophobicContact CG-CB 4.23Å; L64-L310 HydrophobicContact CB-CD1 3.97Å; L64-L310 HydrophobicContact CD1-CD1 3.96Å; K67-L310 HydrophobicContact CB-CD2 3.93Å; K67-L310 HydrophobicContact CG-CD2 4.17Å; K285-L310 WeakPolarHBondContact O-CB 3.49Å; K285-L310 PolarHBondContact O-N 3.32Å; L287-L310 HydrophobicContact CB-CD1 4.34Å; L287-L310 HydrophobicContact CB-CD2 4.18Å; L287-L310 HydrophobicContact CB-CG 4.41Å; I308-L310 PolarHBondContact O-N 2.87Å; L310-I314 HydrophobicContact CD2-CD1 3.92Å
311N98.1Very high98.4Very high47 Ų4748.7 Ų48.725%0.25129%0.288SS..  trans-87.9179.6178.170.418.7000112.8M58 R63 L309 S313 I314M58-N311 HydrophobicContact CG-CB 4.42Å; R63-N311 VanDerWaalsContact CD-O 3.24Å; R63-N311 WeakPolarHBondContact CD-O 3.45Å; R63-N311 PolarHBondContact NE-O 3.17Å; R63-N311 VanDerWaalsContact NE-O 3.12Å; L309-N311 VanDerWaalsContact C-N 3.26Å; L309-N311 HydrophobicContact CD2-CB 4.08Å; L309-N311 HydrophobicContact CG-CB 4.05Å; L309-N311 PolarHBondContact O-N 2.75Å; N311-S313 PolarHBondContact O-N 2.91Å; N311-S313 VanDerWaalsContact OD1-CB 3.26Å; N311-S313 WeakPolarHBondContact OD1-CB 3.46Å; N311-S313 PolarHBondContact OD1-N 3.13Å; N311-S313 PolarHBondContact OD1-OG 2.75Å; N311-I314 PolarHBondContact O-N 3.02Å
312S97.2Very high98.5Very high61 Ų6146.7 Ų46.743%0.42729%0.287SS..THydrogen-bonded Turntrans-61.9-10.8-178.556.60000115.8S55 I314S55-S312 VanDerWaalsContact O-CB 3.24Å; S55-S312 WeakPolarHBondContact O-CB 3.33Å; S55-S312 PolarHBondContact O-OG 2.77Å; S312-I314 PolarHBondContact O-N 3.25Å
313S97.9Very high98.5Very high96 Ų9646.8 Ų46.867%0.67129%0.285SS*.THydrogen-bonded Turntrans-69.9-21.717274.50000112.8N311N311-S313 PolarHBondContact O-N 2.91Å; N311-S313 VanDerWaalsContact OD1-CB 3.26Å; N311-S313 WeakPolarHBondContact OD1-CB 3.46Å; N311-S313 PolarHBondContact OD1-N 3.13Å; N311-S313 PolarHBondContact OD1-OG 2.75Å
314I98.6Very high98.4Very high10 Ų1045.8 Ų45.85%0.05128%0.277CS..SBendtrans-94.8117.7171.3-58.5160.8000106.5R63 T66 K67 I308 L310 N311 S312R63-I314 HydrophobicContact CG-CB 3.84Å; R63-I314 HydrophobicContact CG-CG2 3.71Å; R63-I314 PolarHBondContact NE-O 3.16Å; T66-I314 HydrophobicContact CG2-CG2 3.94Å; K67-I314 HydrophobicContact CB-CG2 4.4Å; I308-I314 HydrophobicContact CG2-CD1 4.37Å; L310-I314 HydrophobicContact CD2-CD1 3.92Å; N311-I314 PolarHBondContact O-N 3.02Å; S312-I314 PolarHBondContact O-N 3.25Å
315P98.3Very high98.3Very high80 Ų8045.3 Ų45.352%0.51928%0.278SS..PPolyproline II helixtrans-67152.8178.527.7-32.4000110.4T66T66-P315 WeakPolarHBondContact CB-O 3.26Å; T66-P315 HydrophobicContact CG2-CG 4.19Å; T66-P315 PolarHBondContact OG1-O 3.2Å; T66-P315 VanDerWaalsContact OG1-O 3.06Å
316E98.8Very high98.3Very high35 Ų3551.8 Ų51.816%0.16430%0.301CS..PPolyproline II helixtrans-74.3137.2167.6-67.5175.5111.400109.6A62 R63 P318 K321A62-E316 HydrophobicContact CB-CB 3.83Å; A62-E316 HydrophobicContact CB-CG 4.21Å; R63-E316 HydrophobicContact CB-CG 4.25Å; E316-P318 WeakPolarHBondContact O-CD 3.45Å; E316-K321 HydrophobicContact CB-CD 4.09Å; E316-K321 WeakPolarHBondContact OE2-CE 3.1Å; E316-K321 IonicContact OE2-NZ 2.83Å; E316-K321 PolarHBondContact OE2-NZ 3.38Å
317D98.8Very high98.1Very high31 Ų3152.4 Ų52.417%0.16630%0.301CS..PPolyproline II helixtrans-61.7124.5173.7-177.1-88.1000110.9A62 F65 T66 S319 I320 K321A62-D317 WeakPolarHBondContact O-CB 3.46Å; A62-D317 PolarHBondContact O-N 2.85Å; F65-D317 HydrophobicContact CB-CB 4.35Å; F65-D317 HydrophobicContact CD1-CB 3.58Å; F65-D317 VanDerWaalsContact CD1-CG 3.48Å; F65-D317 WeakPolarHBondContact CD1-OD2 3.47Å; F65-D317 HydrophobicContact CE1-CB 4.27Å; F65-D317 WeakPolarHBondContact CE1-OD2 3.22Å; F65-D317 HydrophobicContact CG-CB 4.3Å; T66-D317 PolarHBondContact OG1-N 3.23Å; T66-D317 VanDerWaalsContact OG1-N 3.15Å; D317-S319 VanDerWaalsContact C-N 3.31Å; D317-S319 PolarHBondContact O-N 3.07Å; D317-S319 WeakPolarHBondContact OD1-CA 3.29Å; D317-S319 WeakPolarHBondContact OD1-CB 3.14Å; D317-S319 PolarHBondContact OD1-N 3.48Å; D317-I320 HydrophobicContact CB-CB 4.18Å; D317-I320 HydrophobicContact CB-CG1 4.11Å; D317-I320 PolarHBondContact O-N 2.8Å; D317-I320 PolarHBondContact OD1-N 2.74Å; D317-K321 WeakPolarHBondContact O-CB 3.33Å; D317-K321 PolarHBondContact O-N 3.47Å
318P98.6Very high97.8Very high100 Ų10053.4 Ų53.465%0.64931%0.305SS*.Hα-helixtrans-62-35.1-175.4-25.634.7000114.1E316 A322E316-P318 WeakPolarHBondContact O-CD 3.45Å; P318-A322 WeakPolarHBondContact O-CB 3.43Å; P318-A322 PolarHBondContact O-N 3.2Å
319S98.6Very high97.5Very high90 Ų9056.9 Ų56.963%0.62932%0.322SS*.Hα-helixtrans-73.2-46.8-178.5-64.50000110.9D317 K321 A322 D323D317-S319 VanDerWaalsContact C-N 3.31Å; D317-S319 PolarHBondContact O-N 3.07Å; D317-S319 WeakPolarHBondContact OD1-CA 3.29Å; D317-S319 WeakPolarHBondContact OD1-CB 3.14Å; D317-S319 PolarHBondContact OD1-N 3.48Å; S319-K321 VanDerWaalsContact C-N 3.34Å; S319-K321 PolarHBondContact O-N 3.38Å; S319-A322 PolarHBondContact O-N 3.18Å; S319-D323 PolarHBondContact O-N 2.84Å; S319-D323 VanDerWaalsContact O-N 3.1Å
320I98.6Very high97.1Very high13 Ų1361.9 Ų61.97%0.06734%0.343CS..Hα-helixtrans-64.3-41.1176-57.5-60.3000110.5V61 A62 F65 F104 A107 D317 A322 D323 I324V61-I320 HydrophobicContact CG1-CG2 3.98Å; A62-I320 HydrophobicContact CB-CB 4.05Å; A62-I320 HydrophobicContact CB-CG2 3.86Å; F65-I320 HydrophobicContact CB-CG1 4.01Å; F65-I320 HydrophobicContact CD1-CG1 4.03Å; F65-I320 HydrophobicContact CD2-CD1 3.98Å; F65-I320 HydrophobicContact CD2-CG1 3.8Å; F65-I320 HydrophobicContact CE1-CG1 4.42Å; F65-I320 HydrophobicContact CE2-CD1 4.13Å; F65-I320 HydrophobicContact CE2-CG1 4.24Å; F65-I320 HydrophobicContact CG-CD1 4.38Å; F65-I320 HydrophobicContact CG-CG1 3.69Å; F104-I320 HydrophobicContact CD1-CG2 4.18Å; F104-I320 HydrophobicContact CE1-CG2 4.2Å; A107-I320 HydrophobicContact CB-CD1 3.96Å; D317-I320 HydrophobicContact CB-CB 4.18Å; D317-I320 HydrophobicContact CB-CG1 4.11Å; D317-I320 PolarHBondContact O-N 2.8Å; D317-I320 PolarHBondContact OD1-N 2.74Å; I320-A322 PolarHBondContact O-N 2.72Å; I320-D323 WeakPolarHBondContact O-CB 3.42Å; I320-D323 PolarHBondContact O-N 3.35Å; I320-I324 HydrophobicContact CG2-CD1 4.14Å; I320-I324 HydrophobicContact CG2-CG1 4.39Å; I320-I324 WeakPolarHBondContact O-CG1 3.27Å; I320-I324 PolarHBondContact O-N 2.9Å
321K98.4Very high96.6Very high80 Ų8061.9 Ų61.935%0.34834%0.343SS..Hα-helixtrans-62.4-42177-176.5170.2-175.9164.80112.7A62 E316 D317 S319 D323 I324 N325A62-K321 HydrophobicContact CB-CB 4.18Å; E316-K321 HydrophobicContact CB-CD 4.09Å; E316-K321 WeakPolarHBondContact OE2-CE 3.1Å; E316-K321 IonicContact OE2-NZ 2.83Å; E316-K321 PolarHBondContact OE2-NZ 3.38Å; D317-K321 WeakPolarHBondContact O-CB 3.33Å; D317-K321 PolarHBondContact O-N 3.47Å; S319-K321 VanDerWaalsContact C-N 3.34Å; S319-K321 PolarHBondContact O-N 3.38Å; K321-D323 VanDerWaalsContact C-N 3.27Å; K321-D323 PolarHBondContact O-N 3.17Å; K321-I324 PolarHBondContact O-N 3.17Å; K321-N325 PolarHBondContact O-N 2.97Å; K321-N325 PolarHBondContact O-ND2 3.35Å
322A98.4Very high95.9Very high60 Ų6062.8 Ų62.850%0.49635%0.348SS..Hα-helixtrans-62-38.1175.400000111.7P318 S319 I320 N325 K326P318-A322 WeakPolarHBondContact O-CB 3.43Å; P318-A322 PolarHBondContact O-N 3.2Å; S319-A322 PolarHBondContact O-N 3.18Å; I320-A322 PolarHBondContact O-N 2.72Å; A322-N325 PolarHBondContact O-N 2.9Å; A322-K326 PolarHBondContact O-N 3Å; A322-K326 VanDerWaalsContact O-N 3.1Å
323D98.4Very high94.9Very high41 Ų4166.2 Ų66.222%0.21936%0.362CS..Hα-helixtrans-68-47.6176.2-159.27.8000111.6H103 F104 S319 I320 K321 N325 K326 W327H103-D323 IonicContact CD2-OD2 3.84Å; H103-D323 IonicContact CE1-OD2 3.41Å; H103-D323 PolarHBondContact CE1-OD2 3.47Å; H103-D323 IonicContact NE2-OD1 3.23Å; H103-D323 IonicContact NE2-OD2 3.98Å; H103-D323 PolarHBondContact NE2-OD2 2.87Å; F104-D323 HydrophobicContact CE1-CB 4.25Å; S319-D323 PolarHBondContact O-N 2.84Å; S319-D323 VanDerWaalsContact O-N 3.1Å; I320-D323 WeakPolarHBondContact O-CB 3.42Å; I320-D323 PolarHBondContact O-N 3.35Å; K321-D323 VanDerWaalsContact C-N 3.27Å; K321-D323 PolarHBondContact O-N 3.17Å; D323-N325 VanDerWaalsContact C-N 3.27Å; D323-N325 PolarHBondContact O-N 3.25Å; D323-K326 WeakPolarHBondContact O-CB 3.48Å; D323-K326 PolarHBondContact O-N 2.76Å; D323-W327 PolarHBondContact O-N 2.72Å; D323-W327 VanDerWaalsContact O-N 3.11Å; D323-W327 PolarHBondContact OD1-NE1 2.81Å
324I97.5Very high93.7Very high4 Ų466.4 Ų66.42%0.02135%0.348CS..Hα-helixtrans-50.4-49.6171.3-67.1168.4000110.4E42 V61 A62 W92 F104 I320 K321 K326 W327 R328E42-I324 HydrophobicContact CG-CG2 3.74Å; V61-I324 HydrophobicContact CG1-CD1 3.52Å; V61-I324 HydrophobicContact CG1-CG1 4Å; A62-I324 HydrophobicContact CB-CD1 3.9Å; W92-I324 HydrophobicContact CH2-CG2 3.88Å; W92-I324 WeakPolarHBondContact CH2-O 3.45Å; W92-I324 HydrophobicContact CZ2-CG2 3.85Å; F104-I324 HydrophobicContact CE1-CG1 3.74Å; F104-I324 HydrophobicContact CE2-CG1 4.46Å; F104-I324 HydrophobicContact CZ-CB 4.4Å; F104-I324 HydrophobicContact CZ-CG1 3.68Å; I320-I324 HydrophobicContact CG2-CD1 4.14Å; I320-I324 HydrophobicContact CG2-CG1 4.39Å; I320-I324 WeakPolarHBondContact O-CG1 3.27Å; I320-I324 PolarHBondContact O-N 2.9Å; K321-I324 PolarHBondContact O-N 3.17Å; I324-K326 VanDerWaalsContact C-N 3.26Å; I324-K326 PolarHBondContact O-N 3.48Å; I324-W327 PolarHBondContact O-N 2.86Å; I324-R328 WeakPolarHBondContact O-CB 3.5Å; I324-R328 PolarHBondContact O-N 2.9Å
325N96.3Very high92.6Very high85 Ų8566.7 Ų66.746%0.45535%0.352SS..Hα-helixtrans-61-34.2-179.6-69.3-18.1000112.9K321 A322 D323 R328K321-N325 PolarHBondContact O-N 2.97Å; K321-N325 PolarHBondContact O-ND2 3.35Å; A322-N325 PolarHBondContact O-N 2.9Å; D323-N325 VanDerWaalsContact C-N 3.27Å; D323-N325 PolarHBondContact O-N 3.25Å; N325-R328 WeakPolarHBondContact O-CB 3.15Å; N325-R328 PolarHBondContact O-N 3.38Å
326K96.9Very high91.5Very high152 Ų15268 Ų6866%0.66136%0.358SS*.Hα-helixtrans-66.7-43.3176.8-178.4-176.4175.7-173.70111.6A322 D323 I324 R328A322-K326 PolarHBondContact O-N 3Å; A322-K326 VanDerWaalsContact O-N 3.1Å; D323-K326 WeakPolarHBondContact O-CB 3.48Å; D323-K326 PolarHBondContact O-N 2.76Å; I324-K326 VanDerWaalsContact C-N 3.26Å; I324-K326 PolarHBondContact O-N 3.48Å; K326-R328 VanDerWaalsContact C-N 3.33Å
327W95.8Very high90.6Very high52 Ų5272.4 Ų72.420%0.19738%0.379CS..Hα-helixtrans-67.3-39.7174.6-7062.5000110W92 Y96 A99 E100 H103 D323 I324 I329 K330W92-W327 HydrophobicContact CH2-CB 3.72Å; W92-W327 HydrophobicContact CZ3-CB 3.5Å; W92-W327 VanDerWaalsContact CZ3-CB 3.5Å; W92-W327 HydrophobicContact CZ3-CG 4.36Å; Y96-W327 AromaticContact CD1-CE3 3.54Å; Y96-W327 HydrophobicContact CD1-CE3 3.54Å; Y96-W327 AromaticContact CD1-CZ3 3.52Å; Y96-W327 HydrophobicContact CD1-CZ3 3.52Å; Y96-W327 HydrophobicContact CD2-CE3 4.1Å; Y96-W327 HydrophobicContact CE1-CD2 4.35Å; Y96-W327 AromaticContact CE1-CE3 3.36Å; Y96-W327 HydrophobicContact CE1-CE3 3.36Å; Y96-W327 AromaticContact CE1-CZ3 3.76Å; Y96-W327 HydrophobicContact CE1-CZ3 3.76Å; Y96-W327 HydrophobicContact CE2-CB 4.32Å; Y96-W327 AromaticContact CE2-CE3 3.95Å; Y96-W327 HydrophobicContact CE2-CE3 3.95Å; Y96-W327 AromaticContact CG-CE3 3.91Å; Y96-W327 HydrophobicContact CG-CE3 3.91Å; Y96-W327 AromaticContact CG-CZ3 3.98Å; Y96-W327 HydrophobicContact CG-CZ3 3.98Å; Y96-W327 AromaticContact CZ-CE3 3.58Å; Y96-W327 WeakPolarHBondContact OH-CA 3.49Å; Y96-W327 PolarHBondContact OH-O 2.93Å; A99-W327 HydrophobicContact CB-CZ3 4.47Å; E100-W327 HydrophobicContact CB-CE3 4.37Å; E100-W327 HydrophobicContact CB-CZ3 4.23Å; H103-W327 HydrophobicContact CB-CH2 4.04Å; H103-W327 HydrophobicContact CB-CZ2 3.97Å; H103-W327 AromaticContact CD2-CZ2 3.8Å; H103-W327 AromaticContact CG-CZ2 3.62Å; H103-W327 AromaticContact ND1-CZ2 3.94Å; H103-W327 AromaticContact NE2-NE1 3.91Å; D323-W327 PolarHBondContact O-N 2.72Å; D323-W327 VanDerWaalsContact O-N 3.11Å; D323-W327 PolarHBondContact OD1-NE1 2.81Å; I324-W327 PolarHBondContact O-N 2.86Å; W327-I329 PolarHBondContact O-N 3.43Å; W327-K330 PolarHBondContact O-N 2.78Å; W327-K330 VanDerWaalsContact O-N 3.13Å
328R93.1Very high90.1Very high21 Ų2175.7 Ų75.78%0.07939%0.393CS..Hα-helixtrans-53.4-30.5-177.6-170.158.5173.891.2-16.5114.6E42 W92 I324 N325 K326 K330 L331 D332 S335 E409E42-R328 VanDerWaalsContact OE1-CD 3.28Å; E42-R328 WeakPolarHBondContact OE1-CD 3Å; E42-R328 IonicContact OE1-CZ 3.34Å; E42-R328 IonicContact OE1-NE 3.23Å; E42-R328 PolarHBondContact OE1-NE 3.29Å; E42-R328 IonicContact OE2-NE 2.76Å; E42-R328 PolarHBondContact OE2-NE 2.93Å; W92-R328 HydrophobicContact CH2-CB 4.45Å; W92-R328 HydrophobicContact CZ2-CB 4.32Å; I324-R328 WeakPolarHBondContact O-CB 3.5Å; I324-R328 PolarHBondContact O-N 2.9Å; N325-R328 WeakPolarHBondContact O-CB 3.15Å; N325-R328 PolarHBondContact O-N 3.38Å; K326-R328 VanDerWaalsContact C-N 3.33Å; R328-K330 PolarHBondContact O-N 2.04Å; R328-K330 VanDerWaalsContact O-N 3.12Å; R328-L331 VanDerWaalsContact NH1-C 3.26Å; R328-L331 VanDerWaalsContact NH1-CB 3.26Å; R328-L331 PolarHBondContact NH1-O 2.91Å; R328-L331 WeakPolarHBondContact O-CA 3.13Å; R328-L331 VanDerWaalsContact O-CB 3.25Å; R328-L331 WeakPolarHBondContact O-CB 3.08Å; R328-L331 PolarHBondContact O-N 3.33Å; R328-D332 IonicContact CZ-OD1 3.74Å; R328-D332 IonicContact NH1-OD1 2.86Å; R328-D332 PolarHBondContact NH1-OD1 3.06Å; R328-D332 PolarHBondContact O-N 3.12Å; R328-S335 PolarHBondContact NH1-OG 3.45Å; R328-S335 PolarHBondContact NH2-OG 2.8Å; R328-E409 IonicContact CZ-OE1 2.71Å; R328-E409 IonicContact NH2-OE1 3.59Å; R328-E409 PolarHBondContact NH2-OE1 3.39Å; R328-E409 IonicContact NH2-OE2 2.87Å; R328-E409 PolarHBondContact NH2-OE2 3.02Å
329I92.6Very high89.9Confident116 Ų11671.6 Ų71.660%0.59537%0.366SS*.G310 helixtrans-51.3-39178.9-63.1169.7000112.5W327 L331 D332W327-I329 PolarHBondContact O-N 3.43Å; I329-L331 PolarHBondContact O-N 3.37Å; I329-D332 PolarHBondContact O-N 3.45Å
330K89Confident89.7Confident125 Ų12567.5 Ų67.554%0.54334%0.338SS..G310 helixtrans-70-20.2180-165.2178.8176.2-169.40112.6V95 Y96 W327 R328V95-K330 HydrophobicContact CG1-CD 3.68Å; V95-K330 HydrophobicContact CG1-CG 4.04Å; Y96-K330 HydrophobicContact CE1-CD 4.16Å; Y96-K330 WeakPolarHBondContact OH-CB 3.41Å; W327-K330 PolarHBondContact O-N 2.78Å; W327-K330 VanDerWaalsContact O-N 3.13Å; R328-K330 PolarHBondContact O-N 2.04Å; R328-K330 VanDerWaalsContact O-N 3.12Å
331L87.8Confident89.6Confident0 Ų070.8 Ų70.80%035%0.351CS..G310 helixtrans-92.7-15.9-175.3-55.2-175.1000112.7I91 W92 V95 Y96 R328 I329 N333 Y334 S335I91-L331 HydrophobicContact CD1-CB 3.74Å; I91-L331 HydrophobicContact CD1-CD1 4.16Å; I91-L331 HydrophobicContact CD1-CD2 4.43Å; I91-L331 HydrophobicContact CD1-CG 4.33Å; I91-L331 HydrophobicContact CG1-CD1 4.24Å; W92-L331 HydrophobicContact CD2-CD1 3.5Å; W92-L331 VanDerWaalsContact CD2-CD1 3.5Å; W92-L331 VanDerWaalsContact CE2-CD1 3.44Å; W92-L331 HydrophobicContact CE3-CD1 3.95Å; W92-L331 HydrophobicContact CG-CD1 3.83Å; W92-L331 HydrophobicContact CH2-CD1 4.28Å; W92-L331 HydrophobicContact CZ2-CD1 3.86Å; W92-L331 HydrophobicContact CZ3-CD1 4.33Å; V95-L331 HydrophobicContact CB-CD2 3.49Å; V95-L331 VanDerWaalsContact CB-CD2 3.49Å; V95-L331 HydrophobicContact CG1-CD2 3.73Å; V95-L331 HydrophobicContact CG2-CD2 3.52Å; Y96-L331 HydrophobicContact CD2-CD2 4.36Å; Y96-L331 HydrophobicContact CE2-CD1 4.11Å; Y96-L331 HydrophobicContact CE2-CD2 3.84Å; Y96-L331 HydrophobicContact CE2-CG 4.03Å; R328-L331 VanDerWaalsContact NH1-C 3.26Å; R328-L331 VanDerWaalsContact NH1-CB 3.26Å; R328-L331 PolarHBondContact NH1-O 2.91Å; R328-L331 WeakPolarHBondContact O-CA 3.13Å; R328-L331 VanDerWaalsContact O-CB 3.25Å; R328-L331 WeakPolarHBondContact O-CB 3.08Å; R328-L331 PolarHBondContact O-N 3.33Å; I329-L331 PolarHBondContact O-N 3.37Å; L331-N333 VanDerWaalsContact C-N 3.27Å; L331-N333 PolarHBondContact O-N 2.88Å; L331-Y334 WeakPolarHBondContact O-CB 3.41Å; L331-Y334 PolarHBondContact O-N 3.22Å; L331-S335 PolarHBondContact O-OG 3.3Å; L331-S335 VanDerWaalsContact O-OG 3.06Å
332D84.1Confident89.6Confident67 Ų6767.1 Ų67.136%0.35834%0.336SS..Hα-helixtrans-62.9-29.9-172.2-69.6-15.5000113.7R328 I329 Y334 S335 T336R328-D332 IonicContact CZ-OD1 3.74Å; R328-D332 IonicContact NH1-OD1 2.86Å; R328-D332 PolarHBondContact NH1-OD1 3.06Å; R328-D332 PolarHBondContact O-N 3.12Å; I329-D332 PolarHBondContact O-N 3.45Å; D332-Y334 PolarHBondContact O-N 2.99Å; D332-S335 WeakPolarHBondContact O-CB 3.02Å; D332-S335 PolarHBondContact O-N 3.07Å; D332-T336 WeakPolarHBondContact O-CG2 3.48Å; D332-T336 PolarHBondContact O-N 2.83Å; D332-T336 PolarHBondContact O-OG1 2.84Å
333N75.7Confident89.6Confident132 Ų13269.6 Ų69.671%0.70634%0.34SS*.Hα-helixtrans-60.3-31.5175.1-70.5-15000112.5L331 S335 T336L331-N333 VanDerWaalsContact C-N 3.27Å; L331-N333 PolarHBondContact O-N 2.88Å; N333-S335 VanDerWaalsContact C-N 3.32Å; N333-T336 PolarHBondContact O-OG1 3Å
334Y73.6Confident89.6Confident100 Ų10069.8 Ų69.839%0.39234%0.342SS..Hα-helixtrans-82.2-14.2176.6-58.4-81.3000112.9V95 L331 D332 W408 E409V95-Y334 HydrophobicContact CG2-CD2 4.38Å; V95-Y334 HydrophobicContact CG2-CE2 3.78Å; L331-Y334 WeakPolarHBondContact O-CB 3.41Å; L331-Y334 PolarHBondContact O-N 3.22Å; D332-Y334 PolarHBondContact O-N 2.99Å; Y334-W408 AromaticContact CD1-CD1 3.64Å; Y334-W408 HydrophobicContact CD1-CG 4.41Å; Y334-W408 WeakPolarHBondContact O-CB 3.39Å; Y334-E409 PolarHBondContact O-N 3.45Å; Y334-E409 VanDerWaalsContact O-N 3.08Å
335S75.9Confident89.6Confident17 Ų1773.1 Ų73.112%0.11936%0.355CS..Hα-helixtrans-98.6-14.6-169.9-48.90000113R328 L331 D332 N333 E409R328-S335 PolarHBondContact NH1-OG 3.45Å; R328-S335 PolarHBondContact NH2-OG 2.8Å; L331-S335 PolarHBondContact O-OG 3.3Å; L331-S335 VanDerWaalsContact O-OG 3.06Å; D332-S335 WeakPolarHBondContact O-CB 3.02Å; D332-S335 PolarHBondContact O-N 3.07Å; N333-S335 VanDerWaalsContact C-N 3.32Å; S335-E409 WeakPolarHBondContact CB-OE2 3.27Å; S335-E409 PolarHBondContact OG-OE2 3.34Å
336T74.3Confident89.7Confident108 Ų10869 Ų6966%0.66333%0.333SS*.SBendtrans-102.7-21.6-167.644.30000114D332 N333 E338D332-T336 WeakPolarHBondContact O-CG2 3.48Å; D332-T336 PolarHBondContact O-N 2.83Å; D332-T336 PolarHBondContact O-OG1 2.84Å; N333-T336 PolarHBondContact O-OG1 3Å; T336-E338 PolarHBondContact O-N 3.37Å
337Q79.3Confident89.8Confident127 Ų12763.5 Ų63.559%0.59331%0.311SS*.  trans-82.3106.7179.3-169.6175.1-1.800111L339 T407Q337-L339 PolarHBondContact O-N 3.48Å; Q337-T407 WeakPolarHBondContact O-CA 3.41Å
338E89.6Confident89.9Confident99 Ų9961.1 Ų61.146%0.46330%0.302SS..EExtended strand (participates in β ladder)trans-69.6122.1169.2177.2170.1141.500109.8T336 K341 T405T336-E338 PolarHBondContact O-N 3.37Å; E338-K341 WeakPolarHBondContact OE1-CE 3.46Å; E338-T405 HydrophobicContact CB-CG2 4.23Å; E338-T405 HydrophobicContact CG-CG2 3.97Å; E338-T405 PolarHBondContact OE2-OG1 3.22Å
339L93.3Very high90Very high15 Ų1561.2 Ų61.28%0.07931%0.306CS..EExtended strand (participates in β ladder)trans-88.7-36.5175.5-59.7173.2000110.9Q337 I406 W408 L411 I532 S533Q337-L339 PolarHBondContact O-N 3.48Å; L339-I406 PolarHBondContact N-O 3.14Å; L339-W408 HydrophobicContact CD1-CE3 4.16Å; L339-W408 HydrophobicContact CD2-CE3 4.41Å; L339-L411 HydrophobicContact CD1-CD1 3.4Å; L339-L411 HydrophobicContact CD1-CG 4.14Å; L339-I532 HydrophobicContact CB-CG2 4.21Å; L339-S533 VanDerWaalsContact O-CA 3.28Å; L339-S533 WeakPolarHBondContact O-CA 3.34Å; L339-S533 PolarHBondContact O-OG 3.33Å
340G95.1Very high90Very high4 Ų456.6 Ų56.64%0.04128%0.284CS..EExtended strand (participates in β ladder)trans172.4-162.1-179.900000110.8I406 K536G340-I406 PolarHBondContact O-N 2.87Å; G340-K536 WeakPolarHBondContact CA-O 3.19Å
341K97.4Very high90.1Very high81 Ų8154.7 Ų54.735%0.35228%0.277SS..EExtended strand (participates in β ladder)trans-130.7147.3-177.5-61.6-175.4179.6-1750112.8E338 G404 K536 V537 I538E338-K341 WeakPolarHBondContact OE1-CE 3.46Å; K341-G404 CarbonylContact C-O 3.59Å; K341-G404 WeakPolarHBondContact CA-O 3.26Å; K341-K536 PolarHBondContact N-O 3.47Å; K341-V537 CarbonylContact O-C 3.46Å; K341-V537 VanDerWaalsContact O-CA 3.26Å; K341-V537 WeakPolarHBondContact O-CA 3.48Å; K341-I538 PolarHBondContact O-N 3.22Å
342T98.3Very high90.5Very high3 Ų355 Ų552%0.01828%0.279CS..EExtended strand (participates in β ladder)trans-106.4141.8162.9-175.30000110.3V344 L346 E400 G404 I406 I538T342-V344 WeakPolarHBondContact CG2-O 3.41Å; T342-V344 PolarHBondContact OG1-N 2.95Å; T342-V344 PolarHBondContact OG1-O 2.84Å; T342-L346 HydrophobicContact CG2-CD1 4.19Å; T342-L346 HydrophobicContact CG2-CG 4.13Å; T342-E400 HydrophobicContact CG2-CB 3.98Å; T342-G404 PolarHBondContact N-O 2.98Å; T342-G404 WeakPolarHBondContact O-CA 3.01Å; T342-I406 HydrophobicContact CG2-CD1 4.3Å; T342-I406 HydrophobicContact CG2-CG1 4.36Å; T342-I538 WeakPolarHBondContact CA-O 3.31Å
343I98.1Very high91.2Very high113 Ų11351.8 Ų51.858%0.57926%0.262SS*.SBendtrans-1067.9171.357.3168.9000112.4V537 I538 Y539I343-V537 HydrophobicContact CB-CG1 4.47Å; I343-V537 HydrophobicContact CD1-CG1 4.29Å; I343-V537 HydrophobicContact CG1-CG1 4.12Å; I343-V537 HydrophobicContact CG2-CG1 3.66Å; I343-I538 PolarHBondContact N-O 3.36Å; I343-I538 VanDerWaalsContact N-O 3.13Å; I343-Y539 HydrophobicContact CD1-CD1 4.29Å; I343-Y539 HydrophobicContact CD1-CG 4.46Å
344V98.2Very high92.3Very high45 Ų4547 Ų4727%0.27323%0.234SC..SBendtrans-133152.5175.8-58.30000109.5T342 L346 P540T342-V344 WeakPolarHBondContact CG2-O 3.41Å; T342-V344 PolarHBondContact OG1-N 2.95Å; T342-V344 PolarHBondContact OG1-O 2.84Å; V344-L346 HydrophobicContact CG2-CD2 4.07Å; V344-L346 PolarHBondContact O-N 2.82Å; V344-P540 HydrophobicContact CG2-CG 4.34Å
345Y98Very high93.4Very high73 Ų7344.3 Ų44.329%0.28622%0.224SC..  trans-59.6125.2168.2-177.6-112.3000109.5D47 D347 N359 P397 E400D47-Y345 WeakPolarHBondContact OD2-CE2 3.27Å; D47-Y345 PolarHBondContact OD2-OH 3.04Å; Y345-D347 HydrophobicContact CD1-CB 3.8Å; Y345-D347 HydrophobicContact CE1-CB 3.71Å; Y345-D347 PolarHBondContact O-N 3.45Å; Y345-N359 PolarHBondContact O-ND2 3.37Å; Y345-P397 HydrophobicContact CE1-CB 4.33Å; Y345-P397 HydrophobicContact CE2-CB 4.08Å; Y345-P397 WeakPolarHBondContact OH-CB 3.22Å; Y345-P397 WeakPolarHBondContact OH-CG 3.31Å; Y345-E400 WeakPolarHBondContact CA-OE2 3.38Å; Y345-E400 VanDerWaalsContact CB-OE2 3.26Å; Y345-E400 WeakPolarHBondContact CB-OE2 3.48Å; Y345-E400 WeakPolarHBondContact CD2-OE2 3.36Å; Y345-E400 PolarHBondContact N-OE2 2.89Å
346L98.5Very high94.4Very high0 Ų049.3 Ų49.30%024%0.241CC..BIsolated β-bridgetrans-9195.6174.3-56.1178.6000108.1T342 V344 G348 M360 L363 P397 I398 I406 I538 P540T342-L346 HydrophobicContact CG2-CD1 4.19Å; T342-L346 HydrophobicContact CG2-CG 4.13Å; V344-L346 HydrophobicContact CG2-CD2 4.07Å; V344-L346 PolarHBondContact O-N 2.82Å; L346-G348 PolarHBondContact O-N 2.97Å; L346-M360 HydrophobicContact CB-CE 3.38Å; L346-M360 HydrophobicContact CB-SD 4.25Å; L346-M360 HydrophobicContact CD1-CE 4.08Å; L346-M360 HydrophobicContact CG-CE 4.36Å; L346-L363 HydrophobicContact CD1-CD2 3.98Å; L346-L363 HydrophobicContact CD2-CD2 4.24Å; L346-P397 WeakPolarHBondContact O-CA 3.21Å; L346-P397 VanDerWaalsContact O-CB 3.3Å; L346-P397 WeakPolarHBondContact O-CB 3.46Å; L346-I398 HydrophobicContact CB-CB 4.16Å; L346-I398 HydrophobicContact CD1-CB 4.09Å; L346-I398 HydrophobicContact CD1-CD1 4.16Å; L346-I398 HydrophobicContact CG-CB 4.48Å; L346-I398 PolarHBondContact N-O 3.04Å; L346-I398 PolarHBondContact O-N 2.91Å; L346-I406 HydrophobicContact CD1-CD1 4.11Å; L346-I538 HydrophobicContact CD1-CD1 3.95Å; L346-I538 HydrophobicContact CD2-CD1 4.33Å; L346-P540 HydrophobicContact CD2-CG 3.42Å; L346-P540 VanDerWaalsContact CD2-CG 3.42Å
347D98.1Very high95.6Very high35 Ų3544.6 Ų44.619%0.18721%0.211CC..  trans-75.992.9-176.9-171.6-4.2000110.4Y345 S349 S352 C353 C358 N359 M360Y345-D347 HydrophobicContact CD1-CB 3.8Å; Y345-D347 HydrophobicContact CE1-CB 3.71Å; Y345-D347 PolarHBondContact O-N 3.45Å; D347-S349 VanDerWaalsContact OD1-CB 3.27Å; D347-S349 WeakPolarHBondContact OD1-CB 3.22Å; D347-S349 PolarHBondContact OD1-N 3.33Å; D347-S349 PolarHBondContact OD1-OG 3.4Å; D347-S352 VanDerWaalsContact CG-OG 3.3Å; D347-S352 WeakPolarHBondContact OD1-CB 3.3Å; D347-S352 PolarHBondContact OD1-OG 3.06Å; D347-S352 WeakPolarHBondContact OD2-CB 3.26Å; D347-S352 PolarHBondContact OD2-OG 3.28Å; D347-C353 PolarHBondContact O-SG 3.11Å; D347-C353 VanDerWaalsContact O-SG 3.37Å; D347-C358 WeakPolarHBondContact O-CB 3.25Å; D347-N359 WeakPolarHBondContact CB-OD1 3.26Å; D347-N359 PolarHBondContact N-OD1 3.43Å; D347-M360 VanDerWaalsContact O-CB 3.27Å; D347-M360 WeakPolarHBondContact O-CB 3.13Å
348G97.3Very high96.5Very high2 Ų238.6 Ų38.62%0.02118%0.183CC..  trans-101.521.6170.500000113.1L346L346-G348 PolarHBondContact O-N 2.97Å
349S95.8Very high97Very high23 Ų2334.6 Ų34.616%0.16117%0.165CC..  trans-72.7149.4-17969.20000111.8D347 Q351 S352 C353D347-S349 VanDerWaalsContact OD1-CB 3.27Å; D347-S349 WeakPolarHBondContact OD1-CB 3.22Å; D347-S349 PolarHBondContact OD1-N 3.33Å; D347-S349 PolarHBondContact OD1-OG 3.4Å; S349-Q351 VanDerWaalsContact C-N 3.26Å; S349-Q351 PolarHBondContact O-N 2.99Å; S349-S352 PolarHBondContact O-N 3.06Å; S349-S352 VanDerWaalsContact O-N 3.16Å; S349-S352 WeakPolarHBondContact OG-CB 3.21Å; S349-S352 PolarHBondContact OG-N 2.84Å; S349-S352 PolarHBondContact OG-OG 2.85Å; S349-C353 PolarHBondContact O-N 3.27Å
350S91.8Very high97.2Very high19 Ų1933.9 Ų33.913%0.13316%0.162CC..Hα-helixtrans-62-36.5176.8-68.90000111.8S352 R354 F355S350-S352 PolarHBondContact O-N 3.03Å; S350-R354 VanDerWaalsContact O-CB 3.25Å; S350-R354 WeakPolarHBondContact O-CB 3.38Å; S350-R354 PolarHBondContact O-N 3Å; S350-R354 VanDerWaalsContact O-N 3.08Å; S350-R354 PolarHBondContact OG-NE 3.04Å; S350-F355 WeakPolarHBondContact O-CD2 3.48Å
351Q92.5Very high97.4Very high86 Ų8633.7 Ų33.740%0.40216%0.16SC..Hα-helixtrans-64.4-22.3179.1-62.781.2-2.500112.9S349 R356S349-Q351 VanDerWaalsContact C-N 3.26Å; S349-Q351 PolarHBondContact O-N 2.99Å; Q351-R356 PolarHBondContact O-NH2 2.99Å
352S96.4Very high97.5Very high5 Ų529.9 Ų29.94%0.03514%0.143CC..Hα-helixtrans-97-65.1172.9-67.30000110.7D347 S349 S350 R354 F355 R356D347-S352 VanDerWaalsContact CG-OG 3.3Å; D347-S352 WeakPolarHBondContact OD1-CB 3.3Å; D347-S352 PolarHBondContact OD1-OG 3.06Å; D347-S352 WeakPolarHBondContact OD2-CB 3.26Å; D347-S352 PolarHBondContact OD2-OG 3.28Å; S349-S352 PolarHBondContact O-N 3.06Å; S349-S352 VanDerWaalsContact O-N 3.16Å; S349-S352 WeakPolarHBondContact OG-CB 3.21Å; S349-S352 PolarHBondContact OG-N 2.84Å; S349-S352 PolarHBondContact OG-OG 2.85Å; S350-S352 PolarHBondContact O-N 3.03Å; S352-R354 PolarHBondContact O-N 3.04Å; S352-R354 VanDerWaalsContact O-N 3.12Å; S352-F355 PolarHBondContact O-N 3.45Å; S352-R356 PolarHBondContact O-N 2.82Å; S352-R356 PolarHBondContact OG-NH1 2.88Å
353C98.1Very high97.5Very high0 Ų030 Ų300%014%0.143CC..Hα-helixtrans-67.7-16.5-168.6-63.60000115.1D347 S349 C358 G391 I394 F449 Q451D347-C353 PolarHBondContact O-SG 3.11Å; D347-C353 VanDerWaalsContact O-SG 3.37Å; S349-C353 PolarHBondContact O-N 3.27Å; C353-C358 WeakPolarHBondContact CA-SG 3.27Å; C353-C358 HydrophobicContact CB-CB 4Å; C353-C358 WeakPolarHBondContact CB-SG 3.39Å; C353-C358 WeakPolarHBondContact SG-CB 3.39Å; C353-C358 CovalentContact SG-SG 2.04Å; C353-C358 PolarHBondContact SG-SG 3.45Å; C353-G391 WeakPolarHBondContact O-CA 3.43Å; C353-I394 HydrophobicContact CB-CD1 4.18Å; C353-F449 WeakPolarHBondContact O-CD1 3.48Å; C353-Q451 PolarHBondContact O-NE2 2.76Å
354R97.9Very high97.5Very high32 Ų3224.6 Ų24.612%0.12112%0.116CC..THydrogen-bonded Turntrans-97.8-3.6175.1-55.3-173.8-176-165.1-1.5114.1S350 S352 S445 T446 F449S350-R354 VanDerWaalsContact O-CB 3.25Å; S350-R354 WeakPolarHBondContact O-CB 3.38Å; S350-R354 PolarHBondContact O-N 3Å; S350-R354 VanDerWaalsContact O-N 3.08Å; S350-R354 PolarHBondContact OG-NE 3.04Å; S352-R354 PolarHBondContact O-N 3.04Å; S352-R354 VanDerWaalsContact O-N 3.12Å; R354-S445 WeakPolarHBondContact CD-O 3.47Å; R354-S445 PolarHBondContact NH1-O 3.17Å; R354-T446 WeakPolarHBondContact CD-O 3.42Å; R354-F449 WeakPolarHBondContact O-CB 3.37Å
355F97.4Very high97.6Very high43 Ų4322.4 Ų22.419%0.18910%0.103CC..THydrogen-bonded Turntrans-127.3-25.2-174.1-69.9-90.2000113.6S350 S352 Y442 S445 F548S350-F355 WeakPolarHBondContact O-CD2 3.48Å; S352-F355 PolarHBondContact O-N 3.45Å; F355-Y442 HydrophobicContact CB-CE2 4.48Å; F355-Y442 HydrophobicContact CD1-CE1 4.39Å; F355-Y442 HydrophobicContact CD1-CE2 4.48Å; F355-Y442 WeakPolarHBondContact O-CE2 3.46Å; F355-Y442 VanDerWaalsContact O-CZ 3.31Å; F355-Y442 PolarHBondContact O-OH 3.4Å; F355-S445 WeakPolarHBondContact CE2-OG 3.22Å; F355-F548 WeakPolarHBondContact O-CE2 3.3Å; F355-F548 VanDerWaalsContact O-CZ 3.29Å; F355-F548 WeakPolarHBondContact O-CZ 3.42Å
356R98.1Very high97.6Very high122 Ų12221 Ų2146%0.4610%0.1SC..SBendtrans-156.6176.6-176.462.2-175.6112.984.28.3110.5Q351 S352 C358 F449 Q451 F548Q351-R356 PolarHBondContact O-NH2 2.99Å; S352-R356 PolarHBondContact O-N 2.82Å; S352-R356 PolarHBondContact OG-NH1 2.88Å; R356-C358 PolarHBondContact O-N 3.35Å; R356-F449 WeakPolarHBondContact O-CE1 3.42Å; R356-Q451 PolarHBondContact O-NE2 2.98Å; R356-F548 HydrophobicContact CB-CE2 4.3Å
357E98.8Very high97.6Very high9 Ų921 Ų214%0.04210%0.1CC..  trans-56.6129.1169-171177.8164.200110.3N362 V542 E543 G544 R545 I546E357-N362 PolarHBondContact OE1-ND2 3.49Å; E357-V542 HydrophobicContact CB-CG1 4.03Å; E357-V542 HydrophobicContact CG-CG1 4Å; E357-E543 PolarHBondContact OE1-N 2.87Å; E357-G544 PolarHBondContact OE1-N 3.39Å; E357-G544 VanDerWaalsContact OE2-C 3.29Å; E357-G544 WeakPolarHBondContact OE2-CA 3.13Å; E357-G544 PolarHBondContact OE2-N 2.76Å; E357-R545 PolarHBondContact OE1-N 2.84Å; E357-R545 PolarHBondContact OE2-N 2.93Å; E357-I546 HydrophobicContact CB-CB 4.14Å; E357-I546 HydrophobicContact CB-CD1 4.3Å; E357-I546 HydrophobicContact CB-CG1 4.48Å; E357-I546 PolarHBondContact OE2-N 2.79Å
358C98.7Very high97.5Very high1 Ų119.4 Ų19.41%0.0079%0.091CC..  trans-123.1141.5173.673.70000109.9D347 C353 R356 M360 G361 N362 Q451D347-C358 WeakPolarHBondContact O-CB 3.25Å; C353-C358 WeakPolarHBondContact CA-SG 3.27Å; C353-C358 HydrophobicContact CB-CB 4Å; C353-C358 WeakPolarHBondContact CB-SG 3.39Å; C353-C358 WeakPolarHBondContact SG-CB 3.39Å; C353-C358 CovalentContact SG-SG 2.04Å; C353-C358 PolarHBondContact SG-SG 3.45Å; R356-C358 PolarHBondContact O-N 3.35Å; C358-M360 VanDerWaalsContact C-N 3.27Å; C358-M360 PolarHBondContact O-N 3.47Å; C358-G361 PolarHBondContact O-N 3.19Å; C358-G361 PolarHBondContact SG-N 3.1Å; C358-G361 VanDerWaalsContact SG-N 3.38Å; C358-N362 PolarHBondContact O-N 2.96Å; C358-N362 VanDerWaalsContact O-N 3.12Å; C358-Q451 VanDerWaalsContact SG-CD 3.54Å
359N98.8Very high97.4Very high15 Ų1520.4 Ų20.48%0.0810%0.096CC..Hα-helixtrans-70-23.8-17570.7-25.9000113.1Y345 D347 N362 L363 P540 V542Y345-N359 PolarHBondContact O-ND2 3.37Å; D347-N359 WeakPolarHBondContact CB-OD1 3.26Å; D347-N359 PolarHBondContact N-OD1 3.43Å; N359-N362 PolarHBondContact O-N 3.38Å; N359-L363 WeakPolarHBondContact O-CB 3.46Å; N359-L363 PolarHBondContact O-N 3.11Å; N359-P540 HydrophobicContact CB-CB 4.19Å; N359-P540 HydrophobicContact CB-CG 4.29Å; N359-P540 WeakPolarHBondContact CB-O 3.43Å; N359-P540 PolarHBondContact ND2-O 2.01Å; N359-P540 WeakPolarHBondContact O-CB 3.26Å; N359-V542 HydrophobicContact CB-CG2 4.35Å
360M98.8Very high97.3Very high1 Ų121.1 Ų21.11%0.00510%0.098CC..Hα-helixtrans-63.2-42.5168.6-176.663.984.700111.3L346 D347 C358 L363 I364 I394 I398 V414L346-M360 HydrophobicContact CB-CE 3.38Å; L346-M360 HydrophobicContact CB-SD 4.25Å; L346-M360 HydrophobicContact CD1-CE 4.08Å; L346-M360 HydrophobicContact CG-CE 4.36Å; D347-M360 VanDerWaalsContact O-CB 3.27Å; D347-M360 WeakPolarHBondContact O-CB 3.13Å; C358-M360 VanDerWaalsContact C-N 3.27Å; C358-M360 PolarHBondContact O-N 3.47Å; M360-L363 WeakPolarHBondContact O-CB 3.07Å; M360-L363 PolarHBondContact O-N 2.99Å; M360-L363 HydrophobicContact SD-CD2 4.13Å; M360-I364 HydrophobicContact CG-CD1 3.89Å; M360-I364 WeakPolarHBondContact O-CD1 3.34Å; M360-I364 VanDerWaalsContact O-CG1 3.28Å; M360-I364 WeakPolarHBondContact O-CG1 3.43Å; M360-I364 PolarHBondContact O-N 2.95Å; M360-I364 HydrophobicContact SD-CD1 4.23Å; M360-I364 HydrophobicContact SD-CG1 4.45Å; M360-I394 HydrophobicContact CB-CG2 4.35Å; M360-I394 HydrophobicContact CG-CG2 3.65Å; M360-I398 HydrophobicContact CE-CB 4.39Å; M360-I398 HydrophobicContact CE-CD1 4.01Å; M360-I398 HydrophobicContact CE-CG1 3.91Å; M360-V414 HydrophobicContact CE-CG1 4.11Å; M360-V414 HydrophobicContact CE-CG2 3.77Å; M360-V414 HydrophobicContact CG-CG1 4.04Å; M360-V414 HydrophobicContact SD-CG1 3.92Å; M360-V414 HydrophobicContact SD-CG2 4.48Å
361G98.7Very high97.2Very high0 Ų022.6 Ų22.60%011%0.105CC..Hα-helixtrans-61.5-44.1175.600000112.2C358 I364 C365C358-G361 PolarHBondContact O-N 3.19Å; C358-G361 PolarHBondContact SG-N 3.1Å; C358-G361 VanDerWaalsContact SG-N 3.38Å; G361-I364 PolarHBondContact O-N 2.69Å; G361-C365 PolarHBondContact O-N 2.62Å
362N98.9Very high96.8Very high1 Ų119.3 Ų19.31%0.0059%0.09CC..Hα-helixtrans-59.5-48.4174.8-68.4-5.7000111.6E357 C358 N359 I364 C365 D366 A541 R545E357-N362 PolarHBondContact OE1-ND2 3.49Å; C358-N362 PolarHBondContact O-N 2.96Å; C358-N362 VanDerWaalsContact O-N 3.12Å; N359-N362 PolarHBondContact O-N 3.38Å; N362-I364 PolarHBondContact O-N 2.99Å; N362-C365 PolarHBondContact O-N 3.46Å; N362-D366 WeakPolarHBondContact O-CB 3.47Å; N362-D366 PolarHBondContact O-N 2.97Å; N362-A541 PolarHBondContact ND2-O 2.71Å; N362-R545 WeakPolarHBondContact OD1-CD 3.38Å
363L98.8Very high96.1Very high4 Ų423 Ų232%0.02111%0.109CC..Hα-helixtrans-55.2-48.9177.2174.165.4000112.3L346 N359 M360 D366 A367 Y531 I538 P540L346-L363 HydrophobicContact CD1-CD2 3.98Å; L346-L363 HydrophobicContact CD2-CD2 4.24Å; N359-L363 WeakPolarHBondContact O-CB 3.46Å; N359-L363 PolarHBondContact O-N 3.11Å; M360-L363 WeakPolarHBondContact O-CB 3.07Å; M360-L363 PolarHBondContact O-N 2.99Å; M360-L363 HydrophobicContact SD-CD2 4.13Å; L363-D366 PolarHBondContact O-N 3.22Å; L363-A367 WeakPolarHBondContact O-CB 3.01Å; L363-A367 PolarHBondContact O-N 3.19Å; L363-Y531 HydrophobicContact CD1-CD1 3.86Å; L363-Y531 HydrophobicContact CD1-CE1 3.6Å; L363-I538 HydrophobicContact CD1-CB 4.48Å; L363-I538 HydrophobicContact CD1-CD1 3.89Å; L363-I538 HydrophobicContact CD1-CG2 4.43Å; L363-I538 HydrophobicContact CD2-CD1 3.59Å; L363-I538 HydrophobicContact CG-CD1 4.4Å; L363-P540 HydrophobicContact CB-CB 4.06Å; L363-P540 HydrophobicContact CB-CG 4Å
364I98.8Very high94.9Very high0 Ų032 Ų320%014%0.142CC..Hα-helixtrans-66.2-44.9-177.2-63.3162.3000109.9M360 G361 N362 D366 A367 M368 L389 I394 V414 L415 F421 V528M360-I364 HydrophobicContact CG-CD1 3.89Å; M360-I364 WeakPolarHBondContact O-CD1 3.34Å; M360-I364 VanDerWaalsContact O-CG1 3.28Å; M360-I364 WeakPolarHBondContact O-CG1 3.43Å; M360-I364 PolarHBondContact O-N 2.95Å; M360-I364 HydrophobicContact SD-CD1 4.23Å; M360-I364 HydrophobicContact SD-CG1 4.45Å; G361-I364 PolarHBondContact O-N 2.69Å; N362-I364 PolarHBondContact O-N 2.99Å; I364-D366 VanDerWaalsContact C-N 3.34Å; I364-D366 PolarHBondContact O-N 3.31Å; I364-A367 WeakPolarHBondContact O-CB 3.19Å; I364-A367 PolarHBondContact O-N 3.35Å; I364-M368 HydrophobicContact CG2-CG 4.47Å; I364-M368 HydrophobicContact CG2-SD 3.94Å; I364-M368 VanDerWaalsContact O-CG 3.27Å; I364-M368 WeakPolarHBondContact O-CG 3.49Å; I364-M368 PolarHBondContact O-N 2.89Å; I364-L389 HydrophobicContact CB-CD2 3.7Å; I364-L389 HydrophobicContact CD1-CD2 3.9Å; I364-L389 HydrophobicContact CG1-CD2 4.42Å; I364-L389 HydrophobicContact CG2-CD2 3.54Å; I364-I394 HydrophobicContact CD1-CD1 4.21Å; I364-I394 HydrophobicContact CD1-CG1 4Å; I364-V414 HydrophobicContact CD1-CG1 4.08Å; I364-L415 HydrophobicContact CD1-CD2 4.33Å; I364-F421 HydrophobicContact CG2-CE1 4.35Å; I364-F421 HydrophobicContact CG2-CE2 4.05Å; I364-F421 HydrophobicContact CG2-CZ 3.56Å; I364-V528 HydrophobicContact CB-CG2 4.45Å; I364-V528 HydrophobicContact CG1-CG2 4.19Å; I364-V528 HydrophobicContact CG2-CG2 4.01Å
365C98.8Very high92.8Very high0 Ų039.1 Ų39.10%018%0.177CC..Hα-helixtrans-64.9-36.7177.3-94.70000113.1G361 N362 A367 M368 I369 C387G361-C365 PolarHBondContact O-N 2.62Å; N362-C365 PolarHBondContact O-N 3.46Å; C365-A367 VanDerWaalsContact C-N 3.35Å; C365-M368 WeakPolarHBondContact O-CB 3.48Å; C365-M368 PolarHBondContact O-N 3.36Å; C365-I369 WeakPolarHBondContact O-CG1 3.35Å; C365-I369 PolarHBondContact O-N 3.16Å; C365-C387 WeakPolarHBondContact CA-SG 3.5Å; C365-C387 HydrophobicContact CB-CB 3.56Å; C365-C387 WeakPolarHBondContact CB-SG 3.38Å; C365-C387 WeakPolarHBondContact SG-CB 3.44Å; C365-C387 CovalentContact SG-SG 2.05Å; C365-C387 PolarHBondContact SG-SG 3.29Å
366D98.6Very high91Very high44 Ų4439.9 Ų39.924%0.23519%0.191CC..Hα-helixtrans-67.6-38175.2-67.2-8.5000111N362 L363 I364 I369 N370 R545N362-D366 WeakPolarHBondContact O-CB 3.47Å; N362-D366 PolarHBondContact O-N 2.97Å; L363-D366 PolarHBondContact O-N 3.22Å; I364-D366 VanDerWaalsContact C-N 3.34Å; I364-D366 PolarHBondContact O-N 3.31Å; D366-I369 PolarHBondContact O-N 2.88Å; D366-N370 VanDerWaalsContact O-CB 3.29Å; D366-N370 WeakPolarHBondContact O-CB 3.42Å; D366-N370 PolarHBondContact O-N 3Å; D366-R545 IonicContact OD1-CZ 3.61Å; D366-R545 IonicContact OD1-NH1 3.84Å; D366-R545 PolarHBondContact OD1-NH1 3.36Å; D366-R545 IonicContact OD1-NH2 3.91Å; D366-R545 PolarHBondContact OD1-NH2 2.9Å; D366-R545 VanDerWaalsContact OD1-NH2 3.16Å; D366-R545 IonicContact OD2-CZ 3.24Å; D366-R545 IonicContact OD2-NH1 3.28Å; D366-R545 IonicContact OD2-NH2 2.62Å; D366-R545 PolarHBondContact OD2-NH2 2.97Å
367A98.1Very high89.1Confident0 Ų037.3 Ų37.30%019%0.187CC..Hα-helixtrans-62.8-43.917200000112.1L363 I364 C365 I369 N370 N371 V527 V528 Y531L363-A367 WeakPolarHBondContact O-CB 3.01Å; L363-A367 PolarHBondContact O-N 3.19Å; I364-A367 WeakPolarHBondContact O-CB 3.19Å; I364-A367 PolarHBondContact O-N 3.35Å; C365-A367 VanDerWaalsContact C-N 3.35Å; A367-I369 PolarHBondContact O-N 3.18Å; A367-N370 PolarHBondContact O-N 3.08Å; A367-N371 WeakPolarHBondContact O-CB 3.32Å; A367-N371 PolarHBondContact O-N 3.08Å; A367-V527 HydrophobicContact CB-CG1 4.31Å; A367-V528 HydrophobicContact CB-CG2 4.34Å; A367-Y531 VanDerWaalsContact CB-CB 3.45Å; A367-Y531 HydrophobicContact CB-CD1 3.91Å; A367-Y531 HydrophobicContact CB-CD2 4.15Å; A367-Y531 HydrophobicContact CB-CG 3.57Å
368M96.6Very high87.4Confident0 Ų046.6 Ų46.60%023%0.23CC..Hα-helixtrans-57.1-48.5175.1-73.8165.369.700111.6I364 C365 N372 C387 F421 I496 V527I364-M368 HydrophobicContact CG2-CG 4.47Å; I364-M368 HydrophobicContact CG2-SD 3.94Å; I364-M368 VanDerWaalsContact O-CG 3.27Å; I364-M368 WeakPolarHBondContact O-CG 3.49Å; I364-M368 PolarHBondContact O-N 2.89Å; C365-M368 WeakPolarHBondContact O-CB 3.48Å; C365-M368 PolarHBondContact O-N 3.36Å; M368-N372 PolarHBondContact O-N 3.25Å; M368-N372 PolarHBondContact O-ND2 2.92Å; M368-C387 WeakPolarHBondContact CE-SG 3.38Å; M368-C387 PolarHBondContact SD-SG 3.11Å; M368-F421 HydrophobicContact CE-CB 4Å; M368-F421 HydrophobicContact CE-CD1 3.62Å; M368-F421 HydrophobicContact CE-CE1 4.22Å; M368-F421 HydrophobicContact CE-CG 3.83Å; M368-F421 HydrophobicContact CG-CB 4.04Å; M368-F421 HydrophobicContact CG-CD1 4.05Å; M368-F421 HydrophobicContact CG-CD2 3.33Å; M368-F421 HydrophobicContact CG-CE1 4.34Å; M368-F421 HydrophobicContact CG-CE2 3.64Å; M368-F421 HydrophobicContact CG-CG 3.55Å; M368-F421 HydrophobicContact CG-CZ 4.15Å; M368-F421 HydrophobicContact SD-CD1 3.65Å; M368-F421 HydrophobicContact SD-CD2 4.02Å; M368-F421 HydrophobicContact SD-CE1 3.72Å; M368-F421 HydrophobicContact SD-CE2 4.05Å; M368-F421 HydrophobicContact SD-CG 3.82Å; M368-F421 HydrophobicContact SD-CZ 3.92Å; M368-I496 HydrophobicContact CB-CB 4.49Å; M368-I496 HydrophobicContact CB-CD1 4.48Å; M368-I496 HydrophobicContact CB-CG2 4.08Å; M368-I496 HydrophobicContact CE-CB 4.03Å; M368-I496 HydrophobicContact CE-CG2 3.61Å; M368-I496 VanDerWaalsContact O-CD1 3.3Å; M368-I496 WeakPolarHBondContact O-CD1 3.26Å; M368-V527 HydrophobicContact CG-CG1 4.36Å
369I94.8Very high85.9Confident24 Ų2452.1 Ų52.112%0.12326%0.257CS..Hα-helixtrans-64.2-45.5176.9-66.5165000110.4C365 D366 A367 N371 N372 L373 C387 I496C365-I369 WeakPolarHBondContact O-CG1 3.35Å; C365-I369 PolarHBondContact O-N 3.16Å; D366-I369 PolarHBondContact O-N 2.88Å; A367-I369 PolarHBondContact O-N 3.18Å; I369-N371 VanDerWaalsContact C-N 3.34Å; I369-N371 PolarHBondContact O-N 3.31Å; I369-N372 CarbonylContact O-C 3.53Å; I369-N372 PolarHBondContact O-N 3.37Å; I369-N372 VanDerWaalsContact O-N 3.14Å; I369-L373 HydrophobicContact CG2-CD2 4.5Å; I369-L373 PolarHBondContact O-N 3.43Å; I369-C387 HydrophobicContact CD1-CB 4.07Å; I369-C387 HydrophobicContact CG1-CB 4.05Å; I369-I496 HydrophobicContact CG1-CD1 4.3Å
370N94.4Very high84.7Confident37 Ų3754.1 Ų54.120%0.19827%0.265CS..Hα-helixtrans-60.1-42.2-178.9-161.2-95.9000112.7D366 A367 N372 L373 Y531 K534D366-N370 VanDerWaalsContact O-CB 3.29Å; D366-N370 WeakPolarHBondContact O-CB 3.42Å; D366-N370 PolarHBondContact O-N 3Å; A367-N370 PolarHBondContact O-N 3.08Å; N370-N372 VanDerWaalsContact C-N 3.25Å; N370-N372 PolarHBondContact O-N 2.8Å; N370-L373 WeakPolarHBondContact O-CB 3.32Å; N370-L373 WeakPolarHBondContact O-CG 3.34Å; N370-L373 PolarHBondContact O-N 2.85Å; N370-Y531 HydrophobicContact CB-CD2 3.57Å; N370-Y531 HydrophobicContact CB-CE2 3.75Å; N370-K534 PolarHBondContact OD1-NZ 3.42Å
371N88.6Confident83.6Confident51 Ų5157.2 Ų57.227%0.27328%0.277SS..Hα-helixtrans-66.5-29.1178.9-172.679.4000112.5A367 I369 D522 V527A367-N371 WeakPolarHBondContact O-CB 3.32Å; A367-N371 PolarHBondContact O-N 3.08Å; I369-N371 VanDerWaalsContact C-N 3.34Å; I369-N371 PolarHBondContact O-N 3.31Å; N371-D522 PolarHBondContact ND2-OD2 2.73Å; N371-V527 HydrophobicContact CB-CG1 3.8Å; N371-V527 HydrophobicContact CB-CG2 4.33Å
372N84.1Confident82.6Confident17 Ų1757.3 Ų57.39%0.09128%0.278CS..THydrogen-bonded Turntrans-96.811.9-179.5-77-84.3000113.7M368 I369 N370 R374 N382 I496M368-N372 PolarHBondContact O-N 3.25Å; M368-N372 PolarHBondContact O-ND2 2.92Å; I369-N372 CarbonylContact O-C 3.53Å; I369-N372 PolarHBondContact O-N 3.37Å; I369-N372 VanDerWaalsContact O-N 3.14Å; N370-N372 VanDerWaalsContact C-N 3.25Å; N370-N372 PolarHBondContact O-N 2.8Å; N372-R374 PolarHBondContact O-N 3.36Å; N372-N382 PolarHBondContact O-ND2 3.11Å; N372-I496 HydrophobicContact CB-CD1 3.54Å
373L82Confident81.6Confident83 Ų8360 Ų6044%0.43529%0.29SS..  trans-66.1114.9168.1-63.2178.7000108.9I369 N370 W381 N382I369-L373 HydrophobicContact CG2-CD2 4.5Å; I369-L373 PolarHBondContact O-N 3.43Å; N370-L373 WeakPolarHBondContact O-CB 3.32Å; N370-L373 WeakPolarHBondContact O-CG 3.34Å; N370-L373 PolarHBondContact O-N 2.85Å; L373-W381 HydrophobicContact CD2-CZ3 4.42Å; L373-N382 HydrophobicContact CD2-CB 4.38Å; L373-N382 WeakPolarHBondContact CD2-ND2 3.29Å
374R72.7Confident80.9Confident187 Ų18760 Ų6071%0.70629%0.29SS*.  trans-114.7171.3174.3-62.9-166.1-177.2-133.51.3110.2N372 A376 N382N372-R374 PolarHBondContact O-N 3.36Å; R374-A376 PolarHBondContact O-N 3.42Å; R374-A376 VanDerWaalsContact O-N 3.14Å; R374-N382 PolarHBondContact N-OD1 2.84Å; R374-N382 VanDerWaalsContact N-OD1 3.14Å
375H55Low80.7Confident182 Ų18260.1 Ų60.184%0.84329%0.291SS*.  trans-54122.5175.7-72.9-58.6000110.8H383H375-H383 PolarHBondContact O-CE1 3.47Å
376A60.1Low80.6Confident60 Ų6060.3 Ų60.350%0.49629%0.292SS..  trans-64149.7171.900000110.5R374 F380 W381R374-A376 PolarHBondContact O-N 3.42Å; R374-A376 VanDerWaalsContact O-N 3.14Å; A376-F380 WeakPolarHBondContact CA-O 3.44Å; A376-F380 VanDerWaalsContact CB-O 3.3Å; A376-F380 WeakPolarHBondContact CB-O 3.38Å; A376-W381 WeakPolarHBondContact CB-O 3.3Å
377D57.5Low80.6Confident68 Ų6858.2 Ų58.236%0.36428%0.28SS..  trans-108.9-179.8167.467.732.5000110.2M379 F380 H383D377-M379 PolarHBondContact O-N 2.91Å; D377-M379 VanDerWaalsContact O-N 3.12Å; D377-M379 WeakPolarHBondContact OD1-CA 3.32Å; D377-M379 WeakPolarHBondContact OD1-CB 3.32Å; D377-M379 PolarHBondContact OD1-N 2.87Å; D377-F380 PolarHBondContact N-O 3.46Å; D377-F380 PolarHBondContact O-N 3.01Å; D377-F380 WeakPolarHBondContact OD1-CD2 3.4Å; D377-F380 PolarHBondContact OD1-N 3.45Å; D377-H383 IonicContact OD2-NE2 3.9Å
378E62.9Low80.7Confident203 Ų20358.2 Ų58.295%0.94928%0.28SS*.SBendtrans-61.1-20.9-178.8-68.4-172.8170.700113.7
379M67.2Low80.8Confident117 Ų11758.3 Ų58.358%0.57628%0.281SS*.SBendtrans-101.7-26.2-175.6-72.2-171.6-7800113.9D377 K478D377-M379 PolarHBondContact O-N 2.91Å; D377-M379 VanDerWaalsContact O-N 3.12Å; D377-M379 WeakPolarHBondContact OD1-CA 3.32Å; D377-M379 WeakPolarHBondContact OD1-CB 3.32Å; D377-M379 PolarHBondContact OD1-N 2.87Å; M379-K478 WeakPolarHBondContact O-CA 3.44Å
380F73.3Confident80.9Confident57 Ų5757.3 Ų57.325%0.2528%0.276CS..  trans-130.3125.6-172.5-62.9-89.6000111.9A376 D377 N382 T477 K478A376-F380 WeakPolarHBondContact CA-O 3.44Å; A376-F380 VanDerWaalsContact CB-O 3.3Å; A376-F380 WeakPolarHBondContact CB-O 3.38Å; D377-F380 PolarHBondContact N-O 3.46Å; D377-F380 PolarHBondContact O-N 3.01Å; D377-F380 WeakPolarHBondContact OD1-CD2 3.4Å; D377-F380 PolarHBondContact OD1-N 3.45Å; F380-N382 VanDerWaalsContact C-N 3.29Å; F380-N382 PolarHBondContact O-N 3.26Å; F380-T477 WeakPolarHBondContact CA-O 3.5Å; F380-K478 HydrophobicContact CD1-CB 4Å; F380-K478 HydrophobicContact CD1-CG 4.47Å; F380-K478 HydrophobicContact CE1-CB 3.57Å; F380-K478 HydrophobicContact CE1-CD 4.47Å; F380-K478 HydrophobicContact CE1-CG 3.99Å; F380-K478 HydrophobicContact CZ-CB 4.16Å; F380-K478 HydrophobicContact CZ-CD 4.22Å; F380-K478 HydrophobicContact CZ-CG 4.08Å
381W74.8Confident81.1Confident67 Ų6755.6 Ų55.625%0.25427%0.267SS..SBendtrans-69.4-28.517467.6-94.5000112.7L373 A376 S385 L475 C476 T477 C479 P482L373-W381 HydrophobicContact CD2-CZ3 4.42Å; A376-W381 WeakPolarHBondContact CB-O 3.3Å; W381-S385 VanDerWaalsContact CZ2-CB 3.47Å; W381-L475 HydrophobicContact CH2-CD2 4.1Å; W381-L475 HydrophobicContact CZ2-CD2 3.79Å; W381-L475 HydrophobicContact CZ2-CG 4.31Å; W381-C476 PolarHBondContact NE1-O 3.19Å; W381-T477 PolarHBondContact N-O 3.44Å; W381-C479 VanDerWaalsContact CD1-O 3.25Å; W381-P482 HydrophobicContact CD2-CG 3.73Å; W381-P482 HydrophobicContact CE3-CG 4.31Å; W381-P482 HydrophobicContact CG-CG 3.99Å; W381-P482 HydrophobicContact CZ2-CB 3.99Å; W381-P482 HydrophobicContact CZ2-CG 3.97Å
382N79Confident81.4Confident2 Ų253.6 Ų53.61%0.01126%0.258CS..  trans-156.1157.6163.8-170.328000109N372 L373 R374 F380 V384 T477N372-N382 PolarHBondContact O-ND2 3.11Å; L373-N382 HydrophobicContact CD2-CB 4.38Å; L373-N382 WeakPolarHBondContact CD2-ND2 3.29Å; R374-N382 PolarHBondContact N-OD1 2.84Å; R374-N382 VanDerWaalsContact N-OD1 3.14Å; F380-N382 VanDerWaalsContact C-N 3.29Å; F380-N382 PolarHBondContact O-N 3.26Å; N382-V384 VanDerWaalsContact C-N 3.26Å; N382-V384 PolarHBondContact ND2-O 3.42Å; N382-V384 PolarHBondContact O-N 3.39Å; N382-T477 WeakPolarHBondContact O-CB 3.49Å
383H76.6Confident82Confident58 Ų5853.2 Ų53.227%0.26926%0.258SS..SBendtrans-75.6-16.6179.5-67.381.2000113H375 D377 K494H375-H383 PolarHBondContact O-CE1 3.47Å; D377-H383 IonicContact OD2-NE2 3.9Å; H383-K494 WeakPolarHBondContact O-CD 3.49Å
384V85.6Confident82.7Confident4 Ų449.2 Ų49.22%0.02424%0.237CC..  trans-144133.5-177.3-1690000110N382 L423 K494 I496N382-V384 VanDerWaalsContact C-N 3.26Å; N382-V384 PolarHBondContact ND2-O 3.42Å; N382-V384 PolarHBondContact O-N 3.39Å; V384-L423 HydrophobicContact CB-CD1 4.39Å; V384-L423 HydrophobicContact CG1-CD1 3.95Å; V384-L423 HydrophobicContact CG2-CD1 3.5Å; V384-L423 VanDerWaalsContact CG2-CD1 3.5Å; V384-L423 HydrophobicContact CG2-CD2 4.03Å; V384-L423 HydrophobicContact CG2-CG 4.43Å; V384-K494 HydrophobicContact CG1-CB 4.4Å; V384-K494 HydrophobicContact CG2-CB 4.07Å; V384-K494 HydrophobicContact CG2-CD 4.46Å; V384-I496 HydrophobicContact CB-CD1 4.47Å; V384-I496 HydrophobicContact CB-CG1 4.49Å; V384-I496 HydrophobicContact CG1-CD1 3.77Å; V384-I496 HydrophobicContact CG1-CG1 3.45Å; V384-I496 VanDerWaalsContact CG1-CG1 3.45Å
385S93.6Very high83.7Confident2 Ų242.2 Ų42.21%0.01421%0.211CC..  trans-128.8-4.6-178.8580000113.3W381 G454 L475 T477W381-S385 VanDerWaalsContact CZ2-CB 3.47Å; S385-G454 WeakPolarHBondContact O-CA 3.43Å; S385-L475 PolarHBondContact OG-O 3.18Å; S385-T477 VanDerWaalsContact OG-CG2 3.26Å; S385-T477 WeakPolarHBondContact OG-CG2 3.48Å
386M97.8Very high85.7Confident3 Ų333.7 Ų33.72%0.01517%0.172CC..EExtended strand (participates in β ladder)trans-123.6140.5-166.4-67.5166.263.900111.5L431 G453 I455 V474 Y493 V495 I496M386-L431 HydrophobicContact CE-CD1 3.75Å; M386-G453 CarbonylContact C-O 3.44Å; M386-G453 WeakPolarHBondContact CA-O 3.24Å; M386-I455 HydrophobicContact CB-CD1 4.22Å; M386-I455 HydrophobicContact CB-CG1 4.2Å; M386-I455 HydrophobicContact CE-CD1 3.62Å; M386-I455 HydrophobicContact CE-CG1 3.83Å; M386-I455 HydrophobicContact CG-CD1 4.42Å; M386-I455 HydrophobicContact CG-CG1 3.99Å; M386-V474 HydrophobicContact CE-CB 3.95Å; M386-V474 HydrophobicContact CE-CG1 3.45Å; M386-V474 VanDerWaalsContact CE-CG1 3.45Å; M386-V474 HydrophobicContact CG-CB 4.41Å; M386-V474 HydrophobicContact SD-CB 3.73Å; M386-V474 HydrophobicContact SD-CG1 3.96Å; M386-V474 HydrophobicContact SD-CG2 4.31Å; M386-Y493 HydrophobicContact SD-CD1 3.88Å; M386-Y493 HydrophobicContact SD-CG 4.32Å; M386-V495 HydrophobicContact CB-CG1 4.41Å; M386-V495 HydrophobicContact CB-CG2 4.14Å; M386-V495 HydrophobicContact CE-CG2 3.84Å; M386-V495 HydrophobicContact SD-CG2 4.38Å; M386-I496 PolarHBondContact O-N 2.64Å
387C98.5Very high87.5Confident0 Ų031.1 Ų31.10%015%0.15CC..EExtended strand (participates in β ladder)trans-131.9142.1171.5168.70000110.7C365 M368 I369 V452 G453 I496C365-C387 WeakPolarHBondContact CA-SG 3.5Å; C365-C387 HydrophobicContact CB-CB 3.56Å; C365-C387 WeakPolarHBondContact CB-SG 3.38Å; C365-C387 WeakPolarHBondContact SG-CB 3.44Å; C365-C387 CovalentContact SG-SG 2.05Å; C365-C387 PolarHBondContact SG-SG 3.29Å; M368-C387 WeakPolarHBondContact CE-SG 3.38Å; M368-C387 PolarHBondContact SD-SG 3.11Å; I369-C387 HydrophobicContact CD1-CB 4.07Å; I369-C387 HydrophobicContact CG1-CB 4.05Å; C387-V452 WeakPolarHBondContact O-CA 3.36Å; C387-G453 PolarHBondContact N-O 3.02Å; C387-G453 PolarHBondContact O-N 3.11Å; C387-I496 VanDerWaalsContact CA-O 3.28Å; C387-I496 WeakPolarHBondContact CA-O 3.04Å
388I98.8Very high89.3Confident0 Ų028.1 Ų28.10%013%0.134CC..EExtended strand (participates in β ladder)trans-127.3140.7163.263.9177.9000109.7F435 L450 Q451 V452 I455 V495 I496 L497 P498 I511I388-F435 HydrophobicContact CG2-CE2 4.25Å; I388-F435 HydrophobicContact CG2-CZ 3.75Å; I388-L450 HydrophobicContact CB-CD1 4.32Å; I388-L450 HydrophobicContact CB-CD2 4.23Å; I388-L450 HydrophobicContact CD1-CD1 4.3Å; I388-L450 HydrophobicContact CG2-CD1 4.41Å; I388-Q451 WeakPolarHBondContact CA-O 3.32Å; I388-V452 HydrophobicContact CG2-CG1 4.36Å; I388-I455 HydrophobicContact CG2-CD1 3.68Å; I388-V495 HydrophobicContact CD1-CG1 4.34Å; I388-V495 HydrophobicContact CG1-CG1 3.93Å; I388-V495 HydrophobicContact CG2-CG1 4.24Å; I388-I496 PolarHBondContact N-O 3.12Å; I388-L497 HydrophobicContact CD1-CB 4.37Å; I388-L497 HydrophobicContact CD1-CD1 4.22Å; I388-L497 HydrophobicContact CG1-CB 3.68Å; I388-L497 HydrophobicContact CG1-CD1 4.43Å; I388-L497 WeakPolarHBondContact O-CA 3.29Å; I388-P498 WeakPolarHBondContact O-CD 3.31Å; I388-I511 HydrophobicContact CD1-CD1 4.1Å
389L98.8Very high90.7Very high2 Ų220 Ų201%0.0110%0.097CC..EExtended strand (participates in β ladder)trans-142.3121.8-178.9170.564.1000108.8I364 I394 L450 Q451 P498I364-L389 HydrophobicContact CB-CD2 3.7Å; I364-L389 HydrophobicContact CD1-CD2 3.9Å; I364-L389 HydrophobicContact CG1-CD2 4.42Å; I364-L389 HydrophobicContact CG2-CD2 3.54Å; L389-I394 HydrophobicContact CD2-CD1 3.82Å; L389-I394 HydrophobicContact CD2-CG1 3.94Å; L389-I394 HydrophobicContact CG-CD1 4.41Å; L389-I394 HydrophobicContact CG-CG1 4.39Å; L389-L450 CarbonylContact O-C 3.53Å; L389-L450 WeakPolarHBondContact O-CA 3.48Å; L389-Q451 HydrophobicContact CB-CB 4.33Å; L389-Q451 PolarHBondContact N-O 2.96Å; L389-Q451 PolarHBondContact O-N 3.01Å; L389-P498 HydrophobicContact CD1-CG 3.47Å; L389-P498 VanDerWaalsContact CD1-CG 3.47Å
390N98.4Very high92Very high4 Ų417 Ų172%0.0218%0.082CC..EExtended strand (participates in β ladder)trans-69.1133.2175.861.7-54.4000110.6G392 G393 F449 L450 L501 D506N390-G392 PolarHBondContact O-N 3.12Å; N390-G393 PolarHBondContact ND2-N 2.97Å; N390-G393 WeakPolarHBondContact O-CA 3.41Å; N390-G393 PolarHBondContact O-N 3.32Å; N390-F449 CarbonylContact C-O 3.46Å; N390-L450 HydrophobicContact CB-CD2 4.37Å; N390-L501 HydrophobicContact CB-CD1 4.06Å; N390-L501 HydrophobicContact CB-CD2 3.93Å; N390-L501 HydrophobicContact CB-CG 4.36Å; N390-D506 PolarHBondContact ND2-OD2 3.33Å
391G98Very high92.7Very high0 Ų022.9 Ų22.90%010%0.102CC..G310 helixtrans-62.1-25.6-178.500000112.9C353 G393 I394 G447 F449C353-G391 WeakPolarHBondContact O-CA 3.43Å; G391-G393 PolarHBondContact O-N 3.42Å; G391-I394 PolarHBondContact O-N 3.33Å; G391-I394 VanDerWaalsContact O-N 3.17Å; G391-G447 PolarHBondContact N-O 3.44Å; G391-F449 PolarHBondContact N-O 2.9Å
392G94.6Very high93.1Very high9 Ų921.5 Ų21.59%0.09310%0.1CC..G310 helixtrans-61.1-26.9170.200000113.9N390 I394 R395 G447N390-G392 PolarHBondContact O-N 3.12Å; G392-I394 VanDerWaalsContact C-N 3.29Å; G392-I394 PolarHBondContact O-N 3.28Å; G392-R395 WeakPolarHBondContact O-CD 3.44Å; G392-R395 PolarHBondContact O-NE 2.92Å; G392-G447 PolarHBondContact N-O 2.95Å
393G95.8Very high93.5Very high9 Ų928 Ų289%0.09314%0.135CC..G310 helixtrans-73-16.6175.300000114.4N390 G391N390-G393 PolarHBondContact ND2-N 2.97Å; N390-G393 WeakPolarHBondContact O-CA 3.41Å; N390-G393 PolarHBondContact O-N 3.32Å; G391-G393 PolarHBondContact O-N 3.42Å
394I97.8Very high94.2Very high0 Ų025.2 Ų25.20%012%0.122CC..  trans-96.6113.5179.5-54.1174.2000108.6C353 M360 I364 L389 G391 G392 V414 Q451C353-I394 HydrophobicContact CB-CD1 4.18Å; M360-I394 HydrophobicContact CB-CG2 4.35Å; M360-I394 HydrophobicContact CG-CG2 3.65Å; I364-I394 HydrophobicContact CD1-CD1 4.21Å; I364-I394 HydrophobicContact CD1-CG1 4Å; L389-I394 HydrophobicContact CD2-CD1 3.82Å; L389-I394 HydrophobicContact CD2-CG1 3.94Å; L389-I394 HydrophobicContact CG-CD1 4.41Å; L389-I394 HydrophobicContact CG-CG1 4.39Å; G391-I394 PolarHBondContact O-N 3.33Å; G391-I394 VanDerWaalsContact O-N 3.17Å; G392-I394 VanDerWaalsContact C-N 3.29Å; G392-I394 PolarHBondContact O-N 3.28Å; I394-V414 HydrophobicContact CG2-CG1 4.06Å; I394-Q451 HydrophobicContact CD1-CG 3.93Å
395R94.3Very high94.6Very high39 Ų3926.5 Ų26.515%0.14713%0.129CC..  trans-110.6-10.6-164-65.7-59.9-146.4157.24.5116.4H118 G392 A413 V414 P416 F417H118-R395 PolarHBondContact CE1-NH2 3.29Å; H118-R395 PolarHBondContact NE2-NH2 3.3Å; G392-R395 WeakPolarHBondContact O-CD 3.44Å; G392-R395 PolarHBondContact O-NE 2.92Å; R395-A413 CarbonylContact C-O 3.57Å; R395-A413 WeakPolarHBondContact CB-O 3.25Å; R395-V414 WeakPolarHBondContact CB-O 3.48Å; R395-V414 PolarHBondContact N-O 3.18Å; R395-P416 HydrophobicContact CB-CG 3.99Å; R395-P416 HydrophobicContact CG-CG 3.69Å; R395-F417 HydrophobicContact CG-CE2 3.92Å; R395-F417 HydrophobicContact CG-CZ 4.3Å
396S96.5Very high94.7Very high3 Ų326.4 Ų26.42%0.02113%0.129CC..  trans-153.4146.2178.8-174.10000110.8A413 V414S396-A413 WeakPolarHBondContact CB-O 3.49Å; S396-A413 PolarHBondContact N-O 3.24Å; S396-V414 WeakPolarHBondContact O-CG2 3.47Å
397P97.1Very high94.5Very high7 Ų726.7 Ų26.75%0.04513%0.131CC..  trans-74.4170.9158.532.1-32.6000111.7D47 S49 Y345 L346D47-P397 HydrophobicContact CB-CG 4.08Å; D47-P397 VanDerWaalsContact OD2-CG 3.25Å; D47-P397 WeakPolarHBondContact OD2-CG 3.33Å; S49-P397 WeakPolarHBondContact CB-O 3.35Å; Y345-P397 HydrophobicContact CE1-CB 4.33Å; Y345-P397 HydrophobicContact CE2-CB 4.08Å; Y345-P397 WeakPolarHBondContact OH-CB 3.22Å; Y345-P397 WeakPolarHBondContact OH-CG 3.31Å; L346-P397 WeakPolarHBondContact O-CA 3.21Å; L346-P397 VanDerWaalsContact O-CB 3.3Å; L346-P397 WeakPolarHBondContact O-CB 3.46Å
398I96.3Very high94.1Very high4 Ų429.3 Ų29.32%0.02114%0.141CC..BIsolated β-bridgetrans-128.9121.2167.9-58.9174.8000108.5L346 M360 I406 N410 L411 V414L346-I398 HydrophobicContact CB-CB 4.16Å; L346-I398 HydrophobicContact CD1-CB 4.09Å; L346-I398 HydrophobicContact CD1-CD1 4.16Å; L346-I398 HydrophobicContact CG-CB 4.48Å; L346-I398 PolarHBondContact N-O 3.04Å; L346-I398 PolarHBondContact O-N 2.91Å; M360-I398 HydrophobicContact CE-CB 4.39Å; M360-I398 HydrophobicContact CE-CD1 4.01Å; M360-I398 HydrophobicContact CE-CG1 3.91Å; I398-I406 HydrophobicContact CD1-CG2 4.22Å; I398-N410 HydrophobicContact CD1-CB 3.86Å; I398-N410 HydrophobicContact CG1-CB 4.18Å; I398-L411 HydrophobicContact CD1-CD2 4.18Å; I398-V414 HydrophobicContact CD1-CG2 3.76Å; I398-V414 HydrophobicContact CG1-CG2 3.87Å
399D93Very high93.7Very high34 Ų3430.3 Ų30.318%0.18215%0.145CC..  trans-78.2137.3178.3-172.4-80.2000111.3R401 N402D399-R401 WeakPolarHBondContact OD1-CA 3.37Å; D399-R401 WeakPolarHBondContact OD1-CB 3.37Å; D399-R401 VanDerWaalsContact OD1-CG 3.26Å; D399-R401 WeakPolarHBondContact OD1-CG 3.35Å; D399-R401 PolarHBondContact OD1-N 2.89Å; D399-N402 PolarHBondContact O-OD1 3Å
400E93.3Very high93.5Very high52 Ų5230.8 Ų30.824%0.24315%0.148CC..SBendtrans-89.9-7.2-176.278.9-6717000113.9T342 Y345 N402 G404T342-E400 HydrophobicContact CG2-CB 3.98Å; Y345-E400 WeakPolarHBondContact CA-OE2 3.38Å; Y345-E400 VanDerWaalsContact CB-OE2 3.26Å; Y345-E400 WeakPolarHBondContact CB-OE2 3.48Å; Y345-E400 WeakPolarHBondContact CD2-OE2 3.36Å; Y345-E400 PolarHBondContact N-OE2 2.89Å; E400-N402 VanDerWaalsContact C-N 3.3Å; E400-N402 PolarHBondContact O-N 2.82Å; E400-G404 WeakPolarHBondContact O-CA 3.49Å; E400-G404 PolarHBondContact O-N 3.09Å
401R89Confident93.2Very high182 Ų18230.7 Ų30.769%0.68715%0.147SC*.THydrogen-bonded Turntrans-83.1-7.9-167.9-54.4170.5172.8-179.1-4.2113.1D399 N403D399-R401 WeakPolarHBondContact OD1-CA 3.37Å; D399-R401 WeakPolarHBondContact OD1-CB 3.37Å; D399-R401 VanDerWaalsContact OD1-CG 3.26Å; D399-R401 WeakPolarHBondContact OD1-CG 3.35Å; D399-R401 PolarHBondContact OD1-N 2.89Å; R401-N403 PolarHBondContact O-N 3.43Å
402N82.5Confident92.8Very high38 Ų3831 Ų3120%0.20315%0.15CC..THydrogen-bonded Turntrans-86.843.7171.968.8-15.6000112.2V52 D399 E400 G404 T405V52-N402 HydrophobicContact CB-CB 4.35Å; V52-N402 HydrophobicContact CG1-CB 3.7Å; V52-N402 HydrophobicContact CG2-CB 3.77Å; D399-N402 PolarHBondContact O-OD1 3Å; E400-N402 VanDerWaalsContact C-N 3.3Å; E400-N402 PolarHBondContact O-N 2.82Å; N402-G404 PolarHBondContact O-N 3.43Å; N402-G404 PolarHBondContact OD1-N 3.11Å; N402-T405 PolarHBondContact OD1-N 3.42Å
403N87.5Confident92.7Very high138 Ų13831.2 Ų31.274%0.73815%0.151SC*.THydrogen-bonded Turntrans60.417.1-166.8-55.5-30.6000114R401 T405R401-N403 PolarHBondContact O-N 3.43Å; N403-T405 PolarHBondContact O-N 3.49Å
404G91.2Very high92.7Very high0 Ų030.8 Ų30.80%015%0.147CC..THydrogen-bonded Turntrans72.48.5179.400000114.9K341 T342 E400 N402 I406K341-G404 CarbonylContact C-O 3.59Å; K341-G404 WeakPolarHBondContact CA-O 3.26Å; T342-G404 PolarHBondContact N-O 2.98Å; T342-G404 WeakPolarHBondContact O-CA 3.01Å; E400-G404 WeakPolarHBondContact O-CA 3.49Å; E400-G404 PolarHBondContact O-N 3.09Å; N402-G404 PolarHBondContact O-N 3.43Å; N402-G404 PolarHBondContact OD1-N 3.11Å; G404-I406 PolarHBondContact O-N 3.26Å
405T94.7Very high92.5Very high30 Ų3031.2 Ų31.218%0.18415%0.149CC..EExtended strand (participates in β ladder)trans-63.7128.7-173-70.30000111.2E338 N402 N403 T407E338-T405 HydrophobicContact CB-CG2 4.23Å; E338-T405 HydrophobicContact CG-CG2 3.97Å; E338-T405 PolarHBondContact OE2-OG1 3.22Å; N402-T405 PolarHBondContact OD1-N 3.42Å; N403-T405 PolarHBondContact O-N 3.49Å; T405-T407 HydrophobicContact CG2-CG2 3.96Å
406I95.6Very high92.3Very high0 Ų029.8 Ų29.80%014%0.144CC..EExtended strand (participates in β ladder)trans-110122.4175.7-52.6176.2000108.8L339 G340 T342 L346 I398 G404 N410 L411 I532 I538L339-I406 PolarHBondContact N-O 3.14Å; G340-I406 PolarHBondContact O-N 2.87Å; T342-I406 HydrophobicContact CG2-CD1 4.3Å; T342-I406 HydrophobicContact CG2-CG1 4.36Å; L346-I406 HydrophobicContact CD1-CD1 4.11Å; I398-I406 HydrophobicContact CD1-CG2 4.22Å; G404-I406 PolarHBondContact O-N 3.26Å; I406-N410 HydrophobicContact CG2-CB 4.38Å; I406-L411 HydrophobicContact CG2-CD2 4.09Å; I406-L411 HydrophobicContact CG2-CG 4.08Å; I406-I532 HydrophobicContact CD1-CD1 4.02Å; I406-I532 HydrophobicContact CD1-CG2 4.05Å; I406-I532 HydrophobicContact CG2-CD1 4.11Å; I406-I538 HydrophobicContact CD1-CD1 3.58Å; I406-I538 HydrophobicContact CD1-CG1 4.2Å
407T93.3Very high91.6Very high10 Ų1033.6 Ų33.66%0.06116%0.161CC..EExtended strand (participates in β ladder)trans-113.4174175.672.20000111.8Q337 T405 E409 N410 L411Q337-T407 WeakPolarHBondContact O-CA 3.41Å; T405-T407 HydrophobicContact CG2-CG2 3.96Å; T407-E409 VanDerWaalsContact C-N 3.29Å; T407-E409 PolarHBondContact O-N 2.77Å; T407-E409 PolarHBondContact OG1-N 2.99Å; T407-N410 PolarHBondContact N-OD1 3.08Å; T407-N410 WeakPolarHBondContact O-CB 3.45Å; T407-N410 PolarHBondContact O-N 2.8Å; T407-N410 PolarHBondContact OG1-N 2.84Å; T407-N410 PolarHBondContact OG1-OD1 3.41Å; T407-N410 VanDerWaalsContact OG1-OD1 3.12Å; T407-L411 PolarHBondContact O-N 3.1Å
408W89.8Confident90.7Very high55 Ų5535.3 Ų35.321%0.20818%0.18CC..Hα-helixtrans-59.1-41.1173.2-163.5-93.9000112.6Y334 L339 N410 L411 A412 I525 N526 S529Y334-W408 AromaticContact CD1-CD1 3.64Å; Y334-W408 HydrophobicContact CD1-CG 4.41Å; Y334-W408 WeakPolarHBondContact O-CB 3.39Å; L339-W408 HydrophobicContact CD1-CE3 4.16Å; L339-W408 HydrophobicContact CD2-CE3 4.41Å; W408-N410 VanDerWaalsContact C-N 3.29Å; W408-N410 PolarHBondContact O-N 3.03Å; W408-L411 PolarHBondContact O-N 2.87Å; W408-A412 WeakPolarHBondContact O-CB 3.49Å; W408-A412 PolarHBondContact O-N 3.41Å; W408-I525 HydrophobicContact CD2-CD1 3.91Å; W408-I525 HydrophobicContact CD2-CG1 4.24Å; W408-I525 VanDerWaalsContact CE2-CD1 3.42Å; W408-I525 HydrophobicContact CE3-CG1 4.37Å; W408-I525 HydrophobicContact CG-CD1 4.34Å; W408-I525 HydrophobicContact CH2-CB 4.15Å; W408-I525 HydrophobicContact CH2-CD1 4.22Å; W408-I525 HydrophobicContact CH2-CG1 3.68Å; W408-I525 HydrophobicContact CH2-CG2 3.66Å; W408-I525 HydrophobicContact CZ2-CB 4.02Å; W408-I525 HydrophobicContact CZ2-CD1 3.62Å; W408-I525 HydrophobicContact CZ2-CG1 3.56Å; W408-I525 HydrophobicContact CZ2-CG2 3.32Å; W408-I525 HydrophobicContact CZ3-CG1 4.12Å; W408-N526 WeakPolarHBondContact CH2-OD1 3.5Å; W408-S529 WeakPolarHBondContact CZ3-OG 3.01Å
409E91.1Very high90.1Very high20 Ų2035.7 Ų35.79%0.09319%0.185CC..Hα-helixtrans-57.8-41.3175175.4-178.8-171.400112.3K50 I91 R328 Y334 S335 T407 A412 A413K50-E409 WeakPolarHBondContact CE-OE2 3.47Å; K50-E409 IonicContact NZ-OE1 3.74Å; K50-E409 IonicContact NZ-OE2 3.81Å; K50-E409 PolarHBondContact NZ-OE2 3.46Å; I91-E409 HydrophobicContact CD1-CB 4.15Å; I91-E409 HydrophobicContact CD1-CG 3.73Å; I91-E409 HydrophobicContact CG1-CG 4.17Å; I91-E409 HydrophobicContact CG2-CB 4.39Å; I91-E409 HydrophobicContact CG2-CG 4.36Å; R328-E409 IonicContact CZ-OE1 2.71Å; R328-E409 IonicContact NH2-OE1 3.59Å; R328-E409 PolarHBondContact NH2-OE1 3.39Å; R328-E409 IonicContact NH2-OE2 2.87Å; R328-E409 PolarHBondContact NH2-OE2 3.02Å; Y334-E409 PolarHBondContact O-N 3.45Å; Y334-E409 VanDerWaalsContact O-N 3.08Å; S335-E409 WeakPolarHBondContact CB-OE2 3.27Å; S335-E409 PolarHBondContact OG-OE2 3.34Å; T407-E409 VanDerWaalsContact C-N 3.29Å; T407-E409 PolarHBondContact O-N 2.77Å; T407-E409 PolarHBondContact OG1-N 2.99Å; E409-A412 PolarHBondContact O-N 2.95Å; E409-A413 PolarHBondContact O-N 3.26Å; E409-A413 VanDerWaalsContact O-N 3.14Å
410N93.1Very high89.7Confident12 Ų1235.7 Ų35.76%0.06419%0.186CC..Hα-helixtrans-61.5-49.2175.7-63.3122.4000110.6I398 I406 T407 W408 A412 A413 V414I398-N410 HydrophobicContact CD1-CB 3.86Å; I398-N410 HydrophobicContact CG1-CB 4.18Å; I406-N410 HydrophobicContact CG2-CB 4.38Å; T407-N410 PolarHBondContact N-OD1 3.08Å; T407-N410 WeakPolarHBondContact O-CB 3.45Å; T407-N410 PolarHBondContact O-N 2.8Å; T407-N410 PolarHBondContact OG1-N 2.84Å; T407-N410 PolarHBondContact OG1-OD1 3.41Å; T407-N410 VanDerWaalsContact OG1-OD1 3.12Å; W408-N410 VanDerWaalsContact C-N 3.29Å; W408-N410 PolarHBondContact O-N 3.03Å; N410-A412 PolarHBondContact O-N 3.49Å; N410-A413 WeakPolarHBondContact O-CB 3.38Å; N410-A413 PolarHBondContact O-N 3.03Å; N410-V414 WeakPolarHBondContact O-CG2 3.48Å; N410-V414 PolarHBondContact O-N 3.46Å
411L92.6Very high89.7Confident2 Ų233.5 Ų33.51%0.0118%0.176CC..Hα-helixtrans-66.1-35.9-179.7-67.2-175.4000113.2L339 I398 I406 T407 W408 A413 V414 L415 I525 V528 I532L339-L411 HydrophobicContact CD1-CD1 3.4Å; L339-L411 HydrophobicContact CD1-CG 4.14Å; I398-L411 HydrophobicContact CD1-CD2 4.18Å; I406-L411 HydrophobicContact CG2-CD2 4.09Å; I406-L411 HydrophobicContact CG2-CG 4.08Å; T407-L411 PolarHBondContact O-N 3.1Å; W408-L411 PolarHBondContact O-N 2.87Å; L411-A413 PolarHBondContact O-N 3Å; L411-V414 WeakPolarHBondContact O-CA 3.43Å; L411-V414 WeakPolarHBondContact O-CB 3.5Å; L411-V414 PolarHBondContact O-N 3.18Å; L411-L415 PolarHBondContact O-N 3.14Å; L411-I525 HydrophobicContact CB-CD1 3.79Å; L411-I525 HydrophobicContact CB-CG1 3.8Å; L411-I525 HydrophobicContact CD1-CG1 4.37Å; L411-V528 HydrophobicContact CD1-CG1 4.28Å; L411-V528 HydrophobicContact CD2-CG1 3.85Å; L411-I532 HydrophobicContact CD1-CD1 4.21Å; L411-I532 HydrophobicContact CD2-CD1 3.8Å
412A90.5Very high89.8Confident6 Ų624.9 Ų24.95%0.0514%0.144CC..Hα-helixtrans-66-27.2175.700000112I91 W408 E409 N410 L415 P416 I525I91-A412 HydrophobicContact CG2-CB 3.41Å; I91-A412 VanDerWaalsContact CG2-CB 3.41Å; W408-A412 WeakPolarHBondContact O-CB 3.49Å; W408-A412 PolarHBondContact O-N 3.41Å; E409-A412 PolarHBondContact O-N 2.95Å; N410-A412 PolarHBondContact O-N 3.49Å; A412-L415 CarbonylContact O-C 3.59Å; A412-P416 WeakPolarHBondContact O-CA 3.18Å; A412-P416 WeakPolarHBondContact O-CB 3.34Å; A412-I525 HydrophobicContact CB-CD1 3.89Å
413A92.1Very high90.1Very high14 Ų1424.7 Ų24.712%0.11614%0.142CC..Hα-helixtrans-73.9-28.5169.500000112.6R395 S396 E409 N410 L411R395-A413 CarbonylContact C-O 3.57Å; R395-A413 WeakPolarHBondContact CB-O 3.25Å; S396-A413 WeakPolarHBondContact CB-O 3.49Å; S396-A413 PolarHBondContact N-O 3.24Å; E409-A413 PolarHBondContact O-N 3.26Å; E409-A413 VanDerWaalsContact O-N 3.14Å; N410-A413 WeakPolarHBondContact O-CB 3.38Å; N410-A413 PolarHBondContact O-N 3.03Å; L411-A413 PolarHBondContact O-N 3Å
414V95.8Very high90.3Very high1 Ų118.2 Ų18.21%0.00611%0.108CC..Hα-helixtrans-76-45.5175.9-174.70000111.4M360 I364 I394 R395 S396 I398 N410 L411 P416M360-V414 HydrophobicContact CE-CG1 4.11Å; M360-V414 HydrophobicContact CE-CG2 3.77Å; M360-V414 HydrophobicContact CG-CG1 4.04Å; M360-V414 HydrophobicContact SD-CG1 3.92Å; M360-V414 HydrophobicContact SD-CG2 4.48Å; I364-V414 HydrophobicContact CD1-CG1 4.08Å; I394-V414 HydrophobicContact CG2-CG1 4.06Å; R395-V414 WeakPolarHBondContact CB-O 3.48Å; R395-V414 PolarHBondContact N-O 3.18Å; S396-V414 WeakPolarHBondContact O-CG2 3.47Å; I398-V414 HydrophobicContact CD1-CG2 3.76Å; I398-V414 HydrophobicContact CG1-CG2 3.87Å; N410-V414 WeakPolarHBondContact O-CG2 3.48Å; N410-V414 PolarHBondContact O-N 3.46Å; L411-V414 WeakPolarHBondContact O-CA 3.43Å; L411-V414 WeakPolarHBondContact O-CB 3.5Å; L411-V414 PolarHBondContact O-N 3.18Å; V414-P416 WeakPolarHBondContact O-CD 3.28Å
415L93.6Very high90.5Very high9 Ų920.4 Ų20.45%0.04712%0.118CC..SBendtrans-125.373.8-174.6-63.4171.8000110.3I364 L411 A412 F417 F421 D524 V528I364-L415 HydrophobicContact CD1-CD2 4.33Å; L411-L415 PolarHBondContact O-N 3.14Å; A412-L415 CarbonylContact O-C 3.59Å; L415-F417 PolarHBondContact O-N 3.37Å; L415-F421 HydrophobicContact CD1-CZ 4.13Å; L415-D524 HydrophobicContact CD1-CB 4.24Å; L415-V528 HydrophobicContact CD1-CB 4.42Å; L415-V528 HydrophobicContact CD1-CG2 3.7Å
416P88.9Confident90.6Very high8 Ų819 Ų195%0.05211%0.109CC..THydrogen-bonded Turntrans-86-7.4-167.637.2-40.3000113.8Q88 R395 A412 V414Q88-P416 HydrophobicContact CG-CG 4.24Å; Q88-P416 VanDerWaalsContact OE1-CB 3.29Å; Q88-P416 PolarHBondContact OE1-O 2.9Å; R395-P416 HydrophobicContact CB-CG 3.99Å; R395-P416 HydrophobicContact CG-CG 3.69Å; A412-P416 WeakPolarHBondContact O-CA 3.18Å; A412-P416 WeakPolarHBondContact O-CB 3.34Å; V414-P416 WeakPolarHBondContact O-CD 3.28Å
417F81.9Confident90.8Very high83 Ų8323.3 Ų23.336%0.36413%0.128SC..THydrogen-bonded Turntrans-78.7-24.4-172.3-57.1-74.9000113.9Q88 H118 R395 L415Q88-F417 HydrophobicContact CG-CD1 4.18Å; Q88-F417 HydrophobicContact CG-CE1 4.03Å; H118-F417 AromaticContact CE1-CE1 3.7Å; R395-F417 HydrophobicContact CG-CE2 3.92Å; R395-F417 HydrophobicContact CG-CZ 4.3Å; L415-F417 PolarHBondContact O-N 3.37Å
418G78.1Confident91Very high44 Ų4422.8 Ų22.845%0.45413%0.125SC..  trans66.437.1-17600000112.8
419G84.9Confident91.4Very high12 Ų1221.4 Ų21.412%0.12412%0.124CC..  trans-81.5-168.8177.900000112.6Q523 D524G419-Q523 WeakPolarHBondContact O-CA 3.16Å; G419-D524 PolarHBondContact N-OD2 2.76Å; G419-D524 VanDerWaalsContact O-CG 3.3Å; G419-D524 PolarHBondContact O-N 3.01Å
420T84.4Confident91.8Very high34 Ų3420.6 Ų20.621%0.20912%0.12CC..EExtended strand (participates in β ladder)trans-123.1154.2174.554.20000110.6D422 P498 N499 D522T420-D422 VanDerWaalsContact CB-OD1 3.29Å; T420-D422 WeakPolarHBondContact CB-OD1 3.48Å; T420-D422 PolarHBondContact OG1-OD1 3.2Å; T420-P498 CarbonylContact O-C 3.55Å; T420-P498 WeakPolarHBondContact O-CA 3.45Å; T420-N499 PolarHBondContact N-OD1 2.92Å; T420-N499 PolarHBondContact O-N 3.43Å; T420-N499 WeakPolarHBondContact OG1-CB 3.14Å; T420-D522 CarbonylContact C-O 3.49Å; T420-D522 VanDerWaalsContact CA-O 3.27Å; T420-D522 WeakPolarHBondContact CA-O 3.3Å; T420-D522 WeakPolarHBondContact CB-O 3.33Å
421F93.1Very high92.1Very high5 Ų520 Ų202%0.02212%0.117CC..EExtended strand (participates in β ladder)trans-97.1102.1168.5-65-43.2000109.5I364 M368 L415 I496 L497 P498 G521 D522 D524 V527 V528I364-F421 HydrophobicContact CG2-CE1 4.35Å; I364-F421 HydrophobicContact CG2-CE2 4.05Å; I364-F421 HydrophobicContact CG2-CZ 3.56Å; M368-F421 HydrophobicContact CE-CB 4Å; M368-F421 HydrophobicContact CE-CD1 3.62Å; M368-F421 HydrophobicContact CE-CE1 4.22Å; M368-F421 HydrophobicContact CE-CG 3.83Å; M368-F421 HydrophobicContact CG-CB 4.04Å; M368-F421 HydrophobicContact CG-CD1 4.05Å; M368-F421 HydrophobicContact CG-CD2 3.33Å; M368-F421 HydrophobicContact CG-CE1 4.34Å; M368-F421 HydrophobicContact CG-CE2 3.64Å; M368-F421 HydrophobicContact CG-CG 3.55Å; M368-F421 HydrophobicContact CG-CZ 4.15Å; M368-F421 HydrophobicContact SD-CD1 3.65Å; M368-F421 HydrophobicContact SD-CD2 4.02Å; M368-F421 HydrophobicContact SD-CE1 3.72Å; M368-F421 HydrophobicContact SD-CE2 4.05Å; M368-F421 HydrophobicContact SD-CG 3.82Å; M368-F421 HydrophobicContact SD-CZ 3.92Å; L415-F421 HydrophobicContact CD1-CZ 4.13Å; F421-I496 HydrophobicContact CB-CG2 4.12Å; F421-L497 CarbonylContact C-O 3.6Å; F421-P498 HydrophobicContact CD1-CB 4.49Å; F421-P498 HydrophobicContact CD1-CG 4.27Å; F421-P498 HydrophobicContact CE1-CG 4.2Å; F421-G521 VanDerWaalsContact O-CA 3.31Å; F421-G521 WeakPolarHBondContact O-CA 3.32Å; F421-D522 PolarHBondContact N-O 3.48Å; F421-D524 HydrophobicContact CD1-CB 4.41Å; F421-D524 HydrophobicContact CD2-CB 4.27Å; F421-D524 HydrophobicContact CE1-CB 3.94Å; F421-D524 VanDerWaalsContact CE2-CA 3.48Å; F421-D524 HydrophobicContact CE2-CB 3.82Å; F421-D524 WeakPolarHBondContact CE2-O 3.18Å; F421-D524 HydrophobicContact CZ-CB 3.63Å; F421-V527 HydrophobicContact CD2-CB 3.75Å; F421-V527 HydrophobicContact CD2-CG1 3.78Å; F421-V527 HydrophobicContact CD2-CG2 3.98Å; F421-V527 HydrophobicContact CE2-CB 4.07Å; F421-V527 HydrophobicContact CE2-CG1 4.11Å; F421-V528 HydrophobicContact CE2-CG2 4.1Å
422D90.6Very high92.4Very high2 Ų222.4 Ų22.41%0.01113%0.127CC..EExtended strand (participates in β ladder)trans-91.2157.6-171.2-68.3-2000111.8T420 I496 L497 N499 H518 S520 G521T420-D422 VanDerWaalsContact CB-OD1 3.29Å; T420-D422 WeakPolarHBondContact CB-OD1 3.48Å; T420-D422 PolarHBondContact OG1-OD1 3.2Å; D422-I496 VanDerWaalsContact O-CA 3.29Å; D422-I496 WeakPolarHBondContact O-CA 3.13Å; D422-I496 WeakPolarHBondContact O-CG2 3.49Å; D422-L497 PolarHBondContact N-O 3.23Å; D422-L497 PolarHBondContact O-N 3.37Å; D422-N499 WeakPolarHBondContact OD2-CB 3.38Å; D422-H518 IonicContact OD2-CD2 3.82Å; D422-H518 IonicContact OD2-CE1 3.77Å; D422-H518 IonicContact OD2-NE2 2.9Å; D422-H518 PolarHBondContact OD2-NE2 2.96Å; D422-S520 WeakPolarHBondContact OD1-CA 3.43Å; D422-G521 PolarHBondContact OD1-N 3.42Å
423L89.3Confident92.7Very high34 Ų3426.6 Ų26.618%0.17814%0.144CC..EExtended strand (participates in β ladder)trans-104.4124.9174.8-179.762.1000109.9V384 K494 I496 H518 D519V384-L423 HydrophobicContact CB-CD1 4.39Å; V384-L423 HydrophobicContact CG1-CD1 3.95Å; V384-L423 HydrophobicContact CG2-CD1 3.5Å; V384-L423 VanDerWaalsContact CG2-CD1 3.5Å; V384-L423 HydrophobicContact CG2-CD2 4.03Å; V384-L423 HydrophobicContact CG2-CG 4.43Å; L423-K494 HydrophobicContact CD1-CB 4.18Å; L423-I496 HydrophobicContact CD1-CG1 4.29Å; L423-H518 WeakPolarHBondContact O-CA 3.25Å; L423-D519 PolarHBondContact N-O 2.75Å; L423-D519 PolarHBondContact O-N 3.42Å
424V91.9Very high93.1Very high1 Ų126 Ų261%0.00614%0.139CC..EExtended strand (participates in β ladder)trans-122.9155.2175.4-60.70000112.4L426 K494 V495 L497 A502 R517 H518V424-L426 HydrophobicContact CB-CG 4.48Å; V424-L426 HydrophobicContact CG2-CD1 3.62Å; V424-L426 HydrophobicContact CG2-CD2 4.42Å; V424-L426 HydrophobicContact CG2-CG 3.75Å; V424-K494 WeakPolarHBondContact O-CA 3.34Å; V424-V495 HydrophobicContact CG2-CB 4.37Å; V424-V495 WeakPolarHBondContact CG2-O 3.44Å; V424-V495 PolarHBondContact N-O 3.21Å; V424-V495 PolarHBondContact O-N 3.35Å; V424-L497 HydrophobicContact CB-CD2 4.04Å; V424-L497 HydrophobicContact CG1-CD2 3.63Å; V424-L497 HydrophobicContact CG2-CD1 4.32Å; V424-L497 HydrophobicContact CG2-CD2 3.34Å; V424-L497 HydrophobicContact CG2-CG 4.5Å; V424-A502 HydrophobicContact CG1-CB 4.22Å; V424-R517 CarbonylContact C-O 3.55Å; V424-R517 WeakPolarHBondContact CA-O 3.38Å; V424-H518 HydrophobicContact CG1-CB 4.21Å
425Q95.6Very high93.2Very high47 Ų4726 Ų2622%0.2214%0.139CC..EExtended strand (participates in β ladder)trans-106.9122.2167.6-68.2-175.119.100110.1I492 Y493 K494 L516 R517Q425-I492 HydrophobicContact CB-CG2 4.03Å; Q425-Y493 WeakPolarHBondContact CA-O 3.47Å; Q425-K494 HydrophobicContact CG-CG 3.82Å; Q425-L516 HydrophobicContact CB-CB 4.17Å; Q425-L516 PolarHBondContact O-N 2.91Å; Q425-R517 HydrophobicContact CB-CB 4.03Å; Q425-R517 HydrophobicContact CG-CB 4.05Å; Q425-R517 PolarHBondContact N-O 3.19Å
426L97.1Very high93.5Very high0 Ų026.2 Ų26.20%014%0.14CC..EExtended strand (participates in β ladder)trans-129.5144.4-175.7-64167.7000110.1V424 T430 L431 I492 Y493 I511 L515V424-L426 HydrophobicContact CB-CG 4.48Å; V424-L426 HydrophobicContact CG2-CD1 3.62Å; V424-L426 HydrophobicContact CG2-CD2 4.42Å; V424-L426 HydrophobicContact CG2-CG 3.75Å; L426-T430 HydrophobicContact CD2-CG2 3.88Å; L426-L431 HydrophobicContact CB-CG 4.07Å; L426-L431 HydrophobicContact CD1-CD2 3.73Å; L426-L431 HydrophobicContact CD1-CG 4.17Å; L426-I492 WeakPolarHBondContact O-CA 3.44Å; L426-Y493 PolarHBondContact N-O 3.09Å; L426-Y493 PolarHBondContact O-N 2.64Å; L426-I511 HydrophobicContact CD2-CG2 4.27Å; L426-L515 HydrophobicContact CD2-CB 3.91Å
427K98.4Very high93.9Very high90 Ų9027.4 Ų27.439%0.39115%0.145SC..EExtended strand (participates in β ladder)trans-67.7151.2165.5-70.9-172.6175.7-175.20110.2S429 T430 L431 E491 L516K427-S429 WeakPolarHBondContact CB-OG 3.46Å; K427-S429 PolarHBondContact O-N 2.74Å; K427-T430 WeakPolarHBondContact O-CB 3.35Å; K427-T430 PolarHBondContact O-N 2.79Å; K427-L431 PolarHBondContact O-N 2.69Å; K427-L431 VanDerWaalsContact O-N 3.08Å; K427-E491 CarbonylContact C-O 3.4Å; K427-E491 WeakPolarHBondContact CA-O 3.48Å; K427-L516 HydrophobicContact CG-CD1 4.35Å
428G98.6Very high94.7Very high0 Ų023.6 Ų23.60%013%0.128CC..Hα-helixtrans-55.7-35.3171.800000112.3T430 L431 K432 L487 K488 M489 E491G428-T430 VanDerWaalsContact C-N 3.31Å; G428-T430 PolarHBondContact O-N 3.19Å; G428-L431 PolarHBondContact O-N 3.22Å; G428-K432 WeakPolarHBondContact O-CB 3.33Å; G428-K432 PolarHBondContact O-N 3.46Å; G428-L487 VanDerWaalsContact O-CD2 3.32Å; G428-L487 WeakPolarHBondContact O-CD2 3.47Å; G428-K488 WeakPolarHBondContact CA-O 3.18Å; G428-M489 CarbonylContact C-O 3.59Å; G428-M489 PolarHBondContact N-O 2.66Å; G428-E491 PolarHBondContact N-O 2.91Å
429S98.6Very high95.7Very high26 Ų2621.5 Ų21.518%0.18211%0.107CC..Hα-helixtrans-59.2-39.8173.660.30000113.3K427 K433 M489K427-S429 WeakPolarHBondContact CB-OG 3.46Å; K427-S429 PolarHBondContact O-N 2.74Å; S429-K433 WeakPolarHBondContact O-CG 3.47Å; S429-K433 PolarHBondContact O-N 3.45Å; S429-K433 VanDerWaalsContact O-N 3.13Å; S429-M489 PolarHBondContact N-O 2.91Å
430T98.7Very high96.3Very high2 Ų223.9 Ų23.91%0.01211%0.114CC..Hα-helixtrans-71.6-41.9179.1-50.80000110.7L426 K427 G428 K432 K433 A434 M510 E514L426-T430 HydrophobicContact CD2-CG2 3.88Å; K427-T430 WeakPolarHBondContact O-CB 3.35Å; K427-T430 PolarHBondContact O-N 2.79Å; G428-T430 VanDerWaalsContact C-N 3.31Å; G428-T430 PolarHBondContact O-N 3.19Å; T430-K432 VanDerWaalsContact C-N 3.35Å; T430-K432 PolarHBondContact O-N 3.15Å; T430-K433 WeakPolarHBondContact O-CB 3.02Å; T430-K433 PolarHBondContact O-N 2.96Å; T430-A434 PolarHBondContact O-N 3.25Å; T430-M510 HydrophobicContact CG2-CG 4.23Å; T430-M510 WeakPolarHBondContact CG2-O 3.4Å; T430-E514 WeakPolarHBondContact CB-OE2 3.36Å; T430-E514 HydrophobicContact CG2-CB 3.76Å; T430-E514 HydrophobicContact CG2-CG 4.44Å; T430-E514 PolarHBondContact OG1-OE2 3.44Å
431L98.4Very high96.8Very high1 Ų124.9 Ų24.91%0.00511%0.114CC..Hα-helixtrans-60.5-43.7173.8-77.6169.4000112.1M386 L426 K427 G428 K433 A434 F435 L487 Y493 V495M386-L431 HydrophobicContact CE-CD1 3.75Å; L426-L431 HydrophobicContact CB-CG 4.07Å; L426-L431 HydrophobicContact CD1-CD2 3.73Å; L426-L431 HydrophobicContact CD1-CG 4.17Å; K427-L431 PolarHBondContact O-N 2.69Å; K427-L431 VanDerWaalsContact O-N 3.08Å; G428-L431 PolarHBondContact O-N 3.22Å; L431-K433 VanDerWaalsContact C-N 3.34Å; L431-K433 PolarHBondContact O-N 3.27Å; L431-A434 WeakPolarHBondContact O-CB 3.42Å; L431-A434 PolarHBondContact O-N 3.44Å; L431-A434 VanDerWaalsContact O-N 3.15Å; L431-F435 VanDerWaalsContact O-CD2 3.24Å; L431-F435 WeakPolarHBondContact O-CD2 3.36Å; L431-F435 PolarHBondContact O-N 2.82Å; L431-L487 HydrophobicContact CB-CD2 4.16Å; L431-L487 HydrophobicContact CD1-CD1 4.14Å; L431-Y493 HydrophobicContact CD1-CD2 4.05Å; L431-Y493 HydrophobicContact CD1-CG 4.05Å; L431-V495 HydrophobicContact CD1-CG2 3.88Å; L431-V495 HydrophobicContact CD2-CG2 3.85Å; L431-V495 HydrophobicContact CG-CG2 4.42Å
432K98.8Very high97Very high52 Ų5227.8 Ų27.823%0.22613%0.126CC..Hα-helixtrans-57.6-46.6174.9179.766.5176.3-154.90111.4G428 T430 A434 F435 E436 V469 L472 L487 M489G428-K432 WeakPolarHBondContact O-CB 3.33Å; G428-K432 PolarHBondContact O-N 3.46Å; T430-K432 VanDerWaalsContact C-N 3.35Å; T430-K432 PolarHBondContact O-N 3.15Å; K432-A434 VanDerWaalsContact C-N 3.32Å; K432-A434 PolarHBondContact O-N 2.96Å; K432-F435 PolarHBondContact O-N 3.41Å; K432-E436 WeakPolarHBondContact O-CG 3.17Å; K432-E436 PolarHBondContact O-N 3.33Å; K432-V469 HydrophobicContact CD-CB 4.1Å; K432-V469 HydrophobicContact CD-CG1 4Å; K432-V469 VanDerWaalsContact NZ-CB 3.27Å; K432-V469 PolarHBondContact NZ-O 3.48Å; K432-L472 HydrophobicContact CD-CD2 4.24Å; K432-L487 HydrophobicContact CB-CD2 4.39Å; K432-M489 HydrophobicContact CB-CE 4.07Å; K432-M489 HydrophobicContact CB-SD 4.07Å; K432-M489 HydrophobicContact CG-CE 4.17Å; K432-M489 HydrophobicContact CG-SD 4.35Å
433K98.8Very high97Very high94 Ų9430.1 Ų30.141%0.40915%0.15SC..Hα-helixtrans-59.2-41.4175.3-69.6169.8-174.9169.70112.1S429 T430 L431 E436 H437 M510 E514S429-K433 WeakPolarHBondContact O-CG 3.47Å; S429-K433 PolarHBondContact O-N 3.45Å; S429-K433 VanDerWaalsContact O-N 3.13Å; T430-K433 WeakPolarHBondContact O-CB 3.02Å; T430-K433 PolarHBondContact O-N 2.96Å; L431-K433 VanDerWaalsContact C-N 3.34Å; L431-K433 PolarHBondContact O-N 3.27Å; K433-E436 PolarHBondContact O-N 2.99Å; K433-H437 WeakPolarHBondContact O-CB 3.21Å; K433-H437 PolarHBondContact O-N 3.1Å; K433-M510 HydrophobicContact CB-CG 4Å; K433-M510 HydrophobicContact CD-CB 4.48Å; K433-E514 IonicContact NZ-OE1 2.66Å; K433-E514 PolarHBondContact NZ-OE1 3.02Å; K433-E514 IonicContact NZ-OE2 3.16Å; K433-E514 PolarHBondContact NZ-OE2 3.05Å
434A98.8Very high97Very high0 Ų034 Ų340%017%0.167CC..Hα-helixtrans-62.4-42.5176.700000111.6T430 L431 K432 H437 S438 F508 M510 I511T430-A434 PolarHBondContact O-N 3.25Å; L431-A434 WeakPolarHBondContact O-CB 3.42Å; L431-A434 PolarHBondContact O-N 3.44Å; L431-A434 VanDerWaalsContact O-N 3.15Å; K432-A434 VanDerWaalsContact C-N 3.32Å; K432-A434 PolarHBondContact O-N 2.96Å; A434-H437 WeakPolarHBondContact O-CB 3.18Å; A434-H437 PolarHBondContact O-N 2.88Å; A434-S438 WeakPolarHBondContact O-CB 3.34Å; A434-S438 PolarHBondContact O-N 3.38Å; A434-F508 HydrophobicContact CB-CD1 4Å; A434-F508 HydrophobicContact CB-CE1 4Å; A434-F508 WeakPolarHBondContact O-CE1 3.48Å; A434-M510 HydrophobicContact CB-SD 4.19Å; A434-I511 HydrophobicContact CB-CD1 4.33Å; A434-I511 HydrophobicContact CB-CG1 4.37Å
435F98.8Very high96.9Very high1 Ų135.6 Ų35.60%0.00418%0.178CC..Hα-helixtrans-68.5-31.6174.8-79.7-70.8000113.3I388 L431 K432 S438 L450 V452 I455 V457 Y459 V469 L472I388-F435 HydrophobicContact CG2-CE2 4.25Å; I388-F435 HydrophobicContact CG2-CZ 3.75Å; L431-F435 VanDerWaalsContact O-CD2 3.24Å; L431-F435 WeakPolarHBondContact O-CD2 3.36Å; L431-F435 PolarHBondContact O-N 2.82Å; K432-F435 PolarHBondContact O-N 3.41Å; F435-S438 VanDerWaalsContact O-CB 3.31Å; F435-S438 WeakPolarHBondContact O-CB 3.28Å; F435-S438 PolarHBondContact O-N 3.37Å; F435-L450 HydrophobicContact CD1-CD1 4.01Å; F435-L450 HydrophobicContact CE1-CB 4.17Å; F435-L450 HydrophobicContact CE1-CD1 3.98Å; F435-L450 HydrophobicContact CG-CD1 4.48Å; F435-L450 HydrophobicContact CZ-CD1 4.39Å; F435-V452 HydrophobicContact CE1-CG1 3.71Å; F435-V452 HydrophobicContact CZ-CG1 3.81Å; F435-I455 HydrophobicContact CE2-CD1 4.02Å; F435-I455 HydrophobicContact CE2-CG2 4.19Å; F435-I455 HydrophobicContact CZ-CD1 3.74Å; F435-I455 HydrophobicContact CZ-CG2 3.79Å; F435-V457 HydrophobicContact CD1-CG2 4.18Å; F435-V457 HydrophobicContact CE1-CB 4.49Å; F435-V457 HydrophobicContact CE1-CG1 4.33Å; F435-Y459 WeakPolarHBondContact CD1-OH 3.09Å; F435-Y459 WeakPolarHBondContact O-CE1 3.39Å; F435-V469 HydrophobicContact CB-CG2 3.76Å; F435-L472 HydrophobicContact CB-CD2 4.32Å; F435-L472 HydrophobicContact CD2-CD1 3.77Å; F435-L472 HydrophobicContact CD2-CD2 3.51Å; F435-L472 HydrophobicContact CD2-CG 4.3Å; F435-L472 HydrophobicContact CE2-CD1 3.79Å; F435-L472 HydrophobicContact CE2-CD2 4.15Å; F435-L472 HydrophobicContact CG-CD1 4.17Å; F435-L472 HydrophobicContact CG-CD2 4.11Å; F435-L472 HydrophobicContact CZ-CD1 4.19Å
436E98.8Very high96.7Very high15 Ų1534.8 Ų34.87%0.0718%0.177CC..Hα-helixtrans-66.4-44170.4-71.1-63.3166.800112K432 K433 S438 V439 H440 D467 R468 V469K432-E436 WeakPolarHBondContact O-CG 3.17Å; K432-E436 PolarHBondContact O-N 3.33Å; K433-E436 PolarHBondContact O-N 2.99Å; E436-S438 VanDerWaalsContact C-N 3.26Å; E436-S438 PolarHBondContact O-N 3.17Å; E436-V439 PolarHBondContact O-N 3.42Å; E436-H440 PolarHBondContact O-N 3.5Å; E436-D467 PolarHBondContact OE2-N 2.87Å; E436-D467 VanDerWaalsContact OE2-N 3.13Å; E436-R468 VanDerWaalsContact CD-N 3.35Å; E436-R468 PolarHBondContact OE1-N 3.11Å; E436-R468 PolarHBondContact OE2-N 2.91Å; E436-V469 HydrophobicContact CG-CG2 4.04Å; E436-V469 VanDerWaalsContact OE1-CB 3.22Å; E436-V469 WeakPolarHBondContact OE1-CB 3.02Å; E436-V469 WeakPolarHBondContact OE1-CG2 3.47Å; E436-V469 PolarHBondContact OE1-N 3.44Å
437H98.7Very high96.6Very high33 Ų3335.2 Ų35.215%0.15318%0.181CC..Hα-helixtrans-58.8-40.8174.5-178.169.5000111.6K433 A434 V439 H440 D506 F508 M510K433-H437 WeakPolarHBondContact O-CB 3.21Å; K433-H437 PolarHBondContact O-N 3.1Å; A434-H437 WeakPolarHBondContact O-CB 3.18Å; A434-H437 PolarHBondContact O-N 2.88Å; H437-V439 PolarHBondContact O-N 3.25Å; H437-H440 AromaticContact CE1-CE1 3.67Å; H437-H440 AromaticContact CE1-ND1 3.82Å; H437-H440 AromaticContact ND1-CE1 3.87Å; H437-H440 AromaticContact ND1-ND1 3.6Å; H437-H440 PolarHBondContact O-N 3.12Å; H437-H440 VanDerWaalsContact O-N 3.08Å; H437-H440 PolarHBondContact O-ND1 2.75Å; H437-D506 PolarHBondContact NE2-O 3.24Å; H437-F508 HydrophobicContact CB-CE1 4.43Å; H437-F508 AromaticContact CD2-CD1 3.82Å; H437-F508 AromaticContact CD2-CD2 3.81Å; H437-F508 AromaticContact CD2-CE1 3.7Å; H437-F508 AromaticContact CD2-CE2 3.73Å; H437-F508 AromaticContact CD2-CG 3.9Å; H437-F508 AromaticContact CD2-CZ 3.67Å; H437-M510 HydrophobicContact CB-CE 3.8Å
438S98.6Very high96.6Very high3 Ų331 Ų312%0.02116%0.163CC..Hα-helixtrans-53.4-26.8-179.7-166.80000114.6A434 F435 E436 E448 F449 L450A434-S438 WeakPolarHBondContact O-CB 3.34Å; A434-S438 PolarHBondContact O-N 3.38Å; F435-S438 VanDerWaalsContact O-CB 3.31Å; F435-S438 WeakPolarHBondContact O-CB 3.28Å; F435-S438 PolarHBondContact O-N 3.37Å; E436-S438 VanDerWaalsContact C-N 3.26Å; E436-S438 PolarHBondContact O-N 3.17Å; S438-E448 WeakPolarHBondContact CA-O 3.45Å; S438-E448 PolarHBondContact OG-O 3.28Å; S438-F449 VanDerWaalsContact OG-CA 3.31Å; S438-F449 WeakPolarHBondContact OG-CA 3.4Å; S438-L450 WeakPolarHBondContact OG-CB 3.35Å; S438-L450 WeakPolarHBondContact OG-CG 3.28Å; S438-L450 PolarHBondContact OG-N 3.34Å
439V98.4Very high96.6Very high0 Ų031.1 Ų31.10%016%0.163CC..THydrogen-bonded Turntrans-12515.9179.9-63.30000113.1E436 H437 R441 Y442 F449 Y459 L461 R468E436-V439 PolarHBondContact O-N 3.42Å; H437-V439 PolarHBondContact O-N 3.25Å; V439-R441 PolarHBondContact O-N 3.26Å; V439-Y442 HydrophobicContact CG1-CD2 4.25Å; V439-Y442 PolarHBondContact O-N 2.86Å; V439-F449 HydrophobicContact CG1-CD2 4.01Å; V439-F449 HydrophobicContact CG1-CE2 3.97Å; V439-Y459 HydrophobicContact CB-CD1 4.35Å; V439-Y459 HydrophobicContact CB-CE1 4.32Å; V439-Y459 HydrophobicContact CG1-CD1 3.89Å; V439-Y459 HydrophobicContact CG1-CD2 4.12Å; V439-Y459 HydrophobicContact CG1-CE1 3.67Å; V439-Y459 HydrophobicContact CG1-CE2 3.92Å; V439-Y459 HydrophobicContact CG1-CG 4.09Å; V439-Y459 HydrophobicContact CG2-CD1 3.57Å; V439-Y459 HydrophobicContact CG2-CE1 3.64Å; V439-Y459 HydrophobicContact CG2-CG 4.36Å; V439-L461 HydrophobicContact CB-CD2 4.24Å; V439-R468 HydrophobicContact CG2-CB 3.75Å; V439-R468 HydrophobicContact CG2-CG 4.49Å; V439-R468 PolarHBondContact O-NH1 3.25Å
440H98Very high96.6Very high61 Ų6129.9 Ų29.928%0.28216%0.155SC..THydrogen-bonded Turntrans-65.3-40.1-173.182.9-79.4000112.7E436 H437 E448 P465 R468E436-H440 PolarHBondContact O-N 3.5Å; H437-H440 AromaticContact CE1-CE1 3.67Å; H437-H440 AromaticContact CE1-ND1 3.82Å; H437-H440 AromaticContact ND1-CE1 3.87Å; H437-H440 AromaticContact ND1-ND1 3.6Å; H437-H440 PolarHBondContact O-N 3.12Å; H437-H440 VanDerWaalsContact O-N 3.08Å; H437-H440 PolarHBondContact O-ND1 2.75Å; H440-E448 IonicContact CE1-OE1 3.23Å; H440-P465 HydrophobicContact CB-CB 4.26Å; H440-P465 WeakPolarHBondContact O-CG 3.35Å; H440-R468 PolarHBondContact O-NH1 2.85Å; H440-R468 VanDerWaalsContact O-NH1 3.08Å
441R95.1Very high96.6Very high55 Ų5529.8 Ų29.821%0.20815%0.154CC..THydrogen-bonded Turntrans-115.229.9175.766.3-175173.1175.6-0.2113E180 V439 G443 E448E180-R441 IonicContact OE2-CZ 3.36Å; E180-R441 IonicContact OE2-NH1 3.55Å; E180-R441 PolarHBondContact OE2-NH1 2.81Å; E180-R441 IonicContact OE2-NH2 3.33Å; V439-R441 PolarHBondContact O-N 3.26Å; R441-G443 PolarHBondContact O-N 2.94Å; R441-E448 WeakPolarHBondContact CG-OE1 3.5Å; R441-E448 IonicContact CZ-OE1 2.71Å; R441-E448 IonicContact CZ-OE2 2.72Å; R441-E448 IonicContact NE-OE1 3.46Å; R441-E448 PolarHBondContact NE-OE1 3.29Å; R441-E448 IonicContact NE-OE2 2.83Å; R441-E448 PolarHBondContact NE-OE2 2.84Å; R441-E448 IonicContact NH2-OE1 2.63Å; R441-E448 IonicContact NH2-OE2 3.28Å; R441-E448 PolarHBondContact NH2-OE2 2.96Å
442Y96.2Very high96.6Very high67 Ų6729.8 Ų29.826%0.26315%0.154SC..THydrogen-bonded Turntrans-47.5138.4179.3-176.3-84.3000112.6F355 V439 F449 L461 F548F355-Y442 HydrophobicContact CB-CE2 4.48Å; F355-Y442 HydrophobicContact CD1-CE1 4.39Å; F355-Y442 HydrophobicContact CD1-CE2 4.48Å; F355-Y442 WeakPolarHBondContact O-CE2 3.46Å; F355-Y442 VanDerWaalsContact O-CZ 3.31Å; F355-Y442 PolarHBondContact O-OH 3.4Å; V439-Y442 HydrophobicContact CG1-CD2 4.25Å; V439-Y442 PolarHBondContact O-N 2.86Å; Y442-F449 HydrophobicContact CD2-CD2 4.13Å; Y442-F449 HydrophobicContact CD2-CE2 4.3Å; Y442-F449 HydrophobicContact CE2-CD2 4.12Å; Y442-F449 HydrophobicContact CE2-CE2 4.01Å; Y442-L461 HydrophobicContact CD1-CD1 3.5Å; Y442-L461 HydrophobicContact CD1-CD2 4.23Å; Y442-L461 HydrophobicContact CE1-CD1 3.51Å; Y442-L461 HydrophobicContact CG-CD1 4.12Å; Y442-L461 HydrophobicContact CG-CD2 4.05Å; Y442-F548 HydrophobicContact CD2-CE1 4.48Å; Y442-F548 AromaticContact CE2-CE1 3.96Å; Y442-F548 HydrophobicContact CE2-CE1 3.96Å; Y442-F548 AromaticContact CE2-CZ 3.71Å; Y442-F548 HydrophobicContact CE2-CZ 3.71Å; Y442-F548 AromaticContact CZ-CZ 3.98Å
443G91.2Very high96.6Very high51 Ų5127.3 Ų27.353%0.52614%0.143SC..THydrogen-bonded Turntrans110.2-14.3-17900000114R441R441-G443 PolarHBondContact O-N 2.94Å
444Q89.9Confident96.6Very high115 Ų11523.1 Ų23.154%0.53713%0.127SC..SBendtrans-95.67.8-175.1-62.2177.74.900114.1T446Q444-T446 HydrophobicContact CB-CG2 3.92Å; Q444-T446 PolarHBondContact O-N 3.28Å
445S90.3Very high96.6Very high34 Ų3423.1 Ų23.124%0.23813%0.127CC..  trans56.927-176.6-162.40000114.7R354 F355R354-S445 WeakPolarHBondContact CD-O 3.47Å; R354-S445 PolarHBondContact NH1-O 3.17Å; F355-S445 WeakPolarHBondContact CE2-OG 3.22Å
446T91.4Very high96.6Very high31 Ų3126 Ų2619%0.1914%0.141CC..  trans-76.3161.6177.750.80000111.8R354 Q444 E448R354-T446 WeakPolarHBondContact CD-O 3.42Å; Q444-T446 HydrophobicContact CB-CG2 3.92Å; Q444-T446 PolarHBondContact O-N 3.28Å; T446-E448 WeakPolarHBondContact CB-OE1 3.33Å; T446-E448 WeakPolarHBondContact CB-OE2 3.49Å; T446-E448 PolarHBondContact OG1-OE1 2.99Å; T446-E448 PolarHBondContact OG1-OE2 3.48Å; T446-E448 VanDerWaalsContact OG1-OE2 3.13Å
447G94.6Very high96.6Very high8 Ų825.4 Ų25.48%0.08214%0.138CC..THydrogen-bonded Turntrans-76-20.8-166.700000116G391 G392 F449 D506G391-G447 PolarHBondContact N-O 3.44Å; G392-G447 PolarHBondContact N-O 2.95Å; G447-F449 VanDerWaalsContact C-N 3.26Å; G447-F449 PolarHBondContact O-N 2.89Å; G447-F449 VanDerWaalsContact O-N 3.13Å; G447-D506 VanDerWaalsContact C-OD2 3.29Å
448E97.7Very high96.6Very high2 Ų225.4 Ų25.41%0.00914%0.14CC..THydrogen-bonded Turntrans-72.4-7.2-165.765.3-86.1-170.900116.1S438 H440 R441 T446 L450 D506 F508S438-E448 WeakPolarHBondContact CA-O 3.45Å; S438-E448 PolarHBondContact OG-O 3.28Å; H440-E448 IonicContact CE1-OE1 3.23Å; R441-E448 WeakPolarHBondContact CG-OE1 3.5Å; R441-E448 IonicContact CZ-OE1 2.71Å; R441-E448 IonicContact CZ-OE2 2.72Å; R441-E448 IonicContact NE-OE1 3.46Å; R441-E448 PolarHBondContact NE-OE1 3.29Å; R441-E448 IonicContact NE-OE2 2.83Å; R441-E448 PolarHBondContact NE-OE2 2.84Å; R441-E448 IonicContact NH2-OE1 2.63Å; R441-E448 IonicContact NH2-OE2 3.28Å; R441-E448 PolarHBondContact NH2-OE2 2.96Å; T446-E448 WeakPolarHBondContact CB-OE1 3.33Å; T446-E448 WeakPolarHBondContact CB-OE2 3.49Å; T446-E448 PolarHBondContact OG1-OE1 2.99Å; T446-E448 PolarHBondContact OG1-OE2 3.48Å; T446-E448 VanDerWaalsContact OG1-OE2 3.13Å; E448-L450 PolarHBondContact O-N 2.87Å; E448-D506 HydrophobicContact CB-CB 4.26Å; E448-F508 HydrophobicContact CB-CE2 3.64Å; E448-F508 HydrophobicContact CB-CZ 4.04Å; E448-F508 VanDerWaalsContact O-CZ 3.31Å; E448-F508 WeakPolarHBondContact O-CZ 3.27Å
449F98.8Very high96.6Very high3 Ų325.2 Ų25.21%0.01314%0.139CC..  trans-62.9124.5179.5-172.8-93.7000111C353 R354 R356 N390 G391 S438 V439 Y442 G447 Y459 I546 F548C353-F449 WeakPolarHBondContact O-CD1 3.48Å; R354-F449 WeakPolarHBondContact O-CB 3.37Å; R356-F449 WeakPolarHBondContact O-CE1 3.42Å; N390-F449 CarbonylContact C-O 3.46Å; G391-F449 PolarHBondContact N-O 2.9Å; S438-F449 VanDerWaalsContact OG-CA 3.31Å; S438-F449 WeakPolarHBondContact OG-CA 3.4Å; V439-F449 HydrophobicContact CG1-CD2 4.01Å; V439-F449 HydrophobicContact CG1-CE2 3.97Å; Y442-F449 HydrophobicContact CD2-CD2 4.13Å; Y442-F449 HydrophobicContact CD2-CE2 4.3Å; Y442-F449 HydrophobicContact CE2-CD2 4.12Å; Y442-F449 HydrophobicContact CE2-CE2 4.01Å; G447-F449 VanDerWaalsContact C-N 3.26Å; G447-F449 PolarHBondContact O-N 2.89Å; G447-F449 VanDerWaalsContact O-N 3.13Å; F449-Y459 HydrophobicContact CE2-CE2 4.26Å; F449-I546 HydrophobicContact CE1-CD1 3.85Å; F449-I546 HydrophobicContact CZ-CD1 4.12Å; F449-I546 HydrophobicContact CZ-CG2 3.82Å; F449-F548 HydrophobicContact CE2-CE1 4.44Å; F449-F548 AromaticContact CE2-CZ 3.76Å; F449-F548 HydrophobicContact CE2-CZ 3.76Å; F449-F548 HydrophobicContact CZ-CE2 4.5Å; F449-F548 AromaticContact CZ-CZ 3.94Å; F449-F548 HydrophobicContact CZ-CZ 3.94Å
450L98.9Very high96.6Very high0 Ų026.1 Ų26.10%014%0.143CC..EExtended strand (participates in β ladder)trans-92.8114.7-170.4-68.4177.3000110.9I388 L389 N390 F435 S438 E448 L501 F508 I546I388-L450 HydrophobicContact CB-CD1 4.32Å; I388-L450 HydrophobicContact CB-CD2 4.23Å; I388-L450 HydrophobicContact CD1-CD1 4.3Å; I388-L450 HydrophobicContact CG2-CD1 4.41Å; L389-L450 CarbonylContact O-C 3.53Å; L389-L450 WeakPolarHBondContact O-CA 3.48Å; N390-L450 HydrophobicContact CB-CD2 4.37Å; F435-L450 HydrophobicContact CD1-CD1 4.01Å; F435-L450 HydrophobicContact CE1-CB 4.17Å; F435-L450 HydrophobicContact CE1-CD1 3.98Å; F435-L450 HydrophobicContact CG-CD1 4.48Å; F435-L450 HydrophobicContact CZ-CD1 4.39Å; S438-L450 WeakPolarHBondContact OG-CB 3.35Å; S438-L450 WeakPolarHBondContact OG-CG 3.28Å; S438-L450 PolarHBondContact OG-N 3.34Å; E448-L450 PolarHBondContact O-N 2.87Å; L450-L501 HydrophobicContact CD2-CD1 3.93Å; L450-F508 HydrophobicContact CD1-CE1 3.93Å; L450-F508 HydrophobicContact CD1-CZ 4.13Å; L450-F508 HydrophobicContact CD2-CE1 4.12Å; L450-F508 HydrophobicContact CD2-CE2 4.37Å; L450-F508 HydrophobicContact CD2-CZ 3.65Å; L450-F508 HydrophobicContact CG-CE1 4.19Å; L450-F508 HydrophobicContact CG-CZ 3.86Å; L450-I546 WeakPolarHBondContact O-CD1 3.41Å
451Q98.9Very high96.5Very high0 Ų025.7 Ų25.70%014%0.143CC..EExtended strand (participates in β ladder)trans-72153.2156.8-55.6-58.7-42.700109.7C353 R356 C358 I388 L389 I394C353-Q451 PolarHBondContact O-NE2 2.76Å; R356-Q451 PolarHBondContact O-NE2 2.98Å; C358-Q451 VanDerWaalsContact SG-CD 3.54Å; I388-Q451 WeakPolarHBondContact CA-O 3.32Å; L389-Q451 HydrophobicContact CB-CB 4.33Å; L389-Q451 PolarHBondContact N-O 2.96Å; L389-Q451 PolarHBondContact O-N 3.01Å; I394-Q451 HydrophobicContact CD1-CG 3.93Å
452V98.9Very high96.6Very high0 Ų027 Ų270%016%0.161CC..EExtended strand (participates in β ladder)trans-143.8155.6-167.5-59.30000114.7C387 I388 F435 I455 R545 I546C387-V452 WeakPolarHBondContact O-CA 3.36Å; I388-V452 HydrophobicContact CG2-CG1 4.36Å; F435-V452 HydrophobicContact CE1-CG1 3.71Å; F435-V452 HydrophobicContact CZ-CG1 3.81Å; V452-I455 HydrophobicContact CB-CB 4.06Å; V452-I455 HydrophobicContact CG1-CB 4.37Å; V452-I455 HydrophobicContact CG2-CB 4.33Å; V452-I455 WeakPolarHBondContact CG2-O 3.4Å; V452-R545 HydrophobicContact CG2-CB 3.72Å; V452-R545 WeakPolarHBondContact O-CD 3.39Å; V452-R545 PolarHBondContact O-NH1 2.93Å; V452-I546 HydrophobicContact CG2-CD1 4.32Å; V452-I546 HydrophobicContact CG2-CG1 3.95Å
453G98.7Very high96.6Very high0 Ų028.7 Ų28.70%017%0.167CC..EExtended strand (participates in β ladder)trans-134.1138.9164.700000110.3M386 C387 I455M386-G453 CarbonylContact C-O 3.44Å; M386-G453 WeakPolarHBondContact CA-O 3.24Å; C387-G453 PolarHBondContact N-O 3.02Å; C387-G453 PolarHBondContact O-N 3.11Å; G453-I455 PolarHBondContact O-N 3.45Å
454G98.2Very high96.9Very high7 Ų734.5 Ų34.57%0.07218%0.177CC..SBendtrans63.420.6-176.700000115S385 L475S385-G454 WeakPolarHBondContact O-CA 3.43Å; G454-L475 WeakPolarHBondContact O-CB 3.5Å; G454-L475 PolarHBondContact O-N 2.89Å
455I98.9Very high97.3Very high0 Ų032.8 Ų32.80%018%0.176CC..EExtended strand (participates in β ladder)trans-134.4134.5177.6-56.1175.6000108.4M386 I388 F435 V452 G453 L472 D473 V474M386-I455 HydrophobicContact CB-CD1 4.22Å; M386-I455 HydrophobicContact CB-CG1 4.2Å; M386-I455 HydrophobicContact CE-CD1 3.62Å; M386-I455 HydrophobicContact CE-CG1 3.83Å; M386-I455 HydrophobicContact CG-CD1 4.42Å; M386-I455 HydrophobicContact CG-CG1 3.99Å; I388-I455 HydrophobicContact CG2-CD1 3.68Å; F435-I455 HydrophobicContact CE2-CD1 4.02Å; F435-I455 HydrophobicContact CE2-CG2 4.19Å; F435-I455 HydrophobicContact CZ-CD1 3.74Å; F435-I455 HydrophobicContact CZ-CG2 3.79Å; V452-I455 HydrophobicContact CB-CB 4.06Å; V452-I455 HydrophobicContact CG1-CB 4.37Å; V452-I455 HydrophobicContact CG2-CB 4.33Å; V452-I455 WeakPolarHBondContact CG2-O 3.4Å; G453-I455 PolarHBondContact O-N 3.45Å; I455-L472 HydrophobicContact CG2-CD1 3.5Å; I455-L472 VanDerWaalsContact CG2-CD1 3.5Å; I455-D473 WeakPolarHBondContact CA-O 3.31Å; I455-V474 HydrophobicContact CG1-CG1 4.26Å; I455-V474 HydrophobicContact CG2-CG1 4.41Å
456H98.8Very high97.6Very high62 Ų6233.6 Ų33.629%0.28719%0.19SC..EExtended strand (participates in β ladder)trans-114.4115.8168.5-71.4171.1000109.7L472 D473 Y484 R545H456-L472 WeakPolarHBondContact O-CA 3.41Å; H456-D473 HydrophobicContact CB-CB 4.4Å; H456-D473 PolarHBondContact N-O 3.31Å; H456-D473 PolarHBondContact O-N 2.85Å; H456-Y484 HydrophobicContact CB-CD1 4.23Å; H456-Y484 HydrophobicContact CB-CE1 4.22Å; H456-Y484 AromaticContact CD2-CE1 3.67Å; H456-Y484 AromaticContact CD2-CZ 3.59Å; H456-Y484 AromaticContact CE1-CD2 3.7Å; H456-Y484 AromaticContact CE1-CE1 3.97Å; H456-Y484 AromaticContact CE1-CE2 3.33Å; H456-Y484 WeakPolarHBondContact CE1-CE2 3.03Å; H456-Y484 AromaticContact CE1-CZ 3.48Å; H456-Y484 VanDerWaalsContact CE1-CZ 3.48Å; H456-Y484 AromaticContact CG-CD1 3.89Å; H456-Y484 AromaticContact CG-CE1 3.64Å; H456-Y484 AromaticContact CG-CZ 3.9Å; H456-Y484 AromaticContact ND1-CD1 3.82Å; H456-Y484 AromaticContact ND1-CD2 3.84Å; H456-Y484 AromaticContact ND1-CE1 3.82Å; H456-Y484 AromaticContact ND1-CE2 3.83Å; H456-Y484 AromaticContact ND1-CG 3.82Å; H456-Y484 AromaticContact ND1-CZ 3.82Å; H456-Y484 AromaticContact NE2-CE1 3.91Å; H456-Y484 AromaticContact NE2-CE2 3.62Å; H456-Y484 AromaticContact NE2-CZ 3.33Å; H456-Y484 VanDerWaalsContact NE2-CZ 3.33Å; H456-Y484 PolarHBondContact NE2-OH 3.4Å; H456-R545 CarbonylContact C-O 3.57Å; H456-R545 WeakPolarHBondContact CA-O 3.48Å
457V98.8Very high97.9Very high1 Ų135.9 Ų35.91%0.00620%0.201CC..EExtended strand (participates in β ladder)trans-117.5140.6-17964.60000111.2F435 Y459 V469 K471 L472 R545 I546 K547F435-V457 HydrophobicContact CD1-CG2 4.18Å; F435-V457 HydrophobicContact CE1-CB 4.49Å; F435-V457 HydrophobicContact CE1-CG1 4.33Å; V457-Y459 HydrophobicContact CG1-CE2 3.78Å; V457-Y459 HydrophobicContact CG2-CD1 4.27Å; V457-Y459 HydrophobicContact CG2-CD2 4.46Å; V457-Y459 HydrophobicContact CG2-CE1 3.8Å; V457-Y459 HydrophobicContact CG2-CE2 4Å; V457-V469 HydrophobicContact CG2-CG1 4.01Å; V457-K471 WeakPolarHBondContact CA-O 3.24Å; V457-L472 HydrophobicContact CB-CD1 3.77Å; V457-L472 HydrophobicContact CG2-CD1 3.88Å; V457-R545 PolarHBondContact N-O 3.44Å; V457-I546 HydrophobicContact CG1-CB 4.11Å; V457-I546 HydrophobicContact CG1-CG1 3.81Å; V457-I546 HydrophobicContact CG1-CG2 3.92Å; V457-K547 PolarHBondContact O-N 3.48Å
458V98.8Very high98.1Very high33 Ų3337.3 Ų37.320%0.220%0.204CC..EExtended strand (participates in β ladder)trans-124.1126.4172.2-170.80000108.9V470 K471 K547V458-V470 HydrophobicContact CB-CG2 3.85Å; V458-V470 HydrophobicContact CG1-CG2 3.64Å; V458-V470 VanDerWaalsContact O-CG2 3.24Å; V458-V470 WeakPolarHBondContact O-CG2 3.12Å; V458-V470 PolarHBondContact O-N 2.81Å; V458-K471 HydrophobicContact CB-CB 3.85Å; V458-K471 HydrophobicContact CG2-CB 3.86Å; V458-K471 HydrophobicContact CG2-CD 4.34Å; V458-K471 PolarHBondContact N-O 3.04Å; V458-K471 PolarHBondContact O-N 3.32Å; V458-K547 CarbonylContact C-O 3.55Å; V458-K547 WeakPolarHBondContact CA-O 3.28Å; V458-K547 HydrophobicContact CG1-CB 4.32Å; V458-K547 HydrophobicContact CG2-CB 4.27Å
459Y98.6Very high98.2Very high0 Ų037.4 Ų37.40%021%0.205CC..EExtended strand (participates in β ladder)trans-105.8150.7177-58.3-73.4000112.1F435 V439 F449 V457 R468 V469 I546 K547 F548 S549F435-Y459 WeakPolarHBondContact CD1-OH 3.09Å; F435-Y459 WeakPolarHBondContact O-CE1 3.39Å; V439-Y459 HydrophobicContact CB-CD1 4.35Å; V439-Y459 HydrophobicContact CB-CE1 4.32Å; V439-Y459 HydrophobicContact CG1-CD1 3.89Å; V439-Y459 HydrophobicContact CG1-CD2 4.12Å; V439-Y459 HydrophobicContact CG1-CE1 3.67Å; V439-Y459 HydrophobicContact CG1-CE2 3.92Å; V439-Y459 HydrophobicContact CG1-CG 4.09Å; V439-Y459 HydrophobicContact CG2-CD1 3.57Å; V439-Y459 HydrophobicContact CG2-CE1 3.64Å; V439-Y459 HydrophobicContact CG2-CG 4.36Å; F449-Y459 HydrophobicContact CE2-CE2 4.26Å; V457-Y459 HydrophobicContact CG1-CE2 3.78Å; V457-Y459 HydrophobicContact CG2-CD1 4.27Å; V457-Y459 HydrophobicContact CG2-CD2 4.46Å; V457-Y459 HydrophobicContact CG2-CE1 3.8Å; V457-Y459 HydrophobicContact CG2-CE2 4Å; Y459-R468 CarbonylContact C-O 3.54Å; Y459-R468 VanDerWaalsContact CA-O 3.25Å; Y459-R468 WeakPolarHBondContact CA-O 3.15Å; Y459-V469 HydrophobicContact CD1-CB 4.5Å; Y459-V469 HydrophobicContact CD1-CG2 3.84Å; Y459-V469 HydrophobicContact CE1-CG2 3.62Å; Y459-I546 HydrophobicContact CD2-CG2 3.95Å; Y459-I546 HydrophobicContact CE2-CG2 3.59Å; Y459-K547 PolarHBondContact N-O 2.94Å; Y459-F548 HydrophobicContact CD2-CD1 4.26Å; Y459-F548 AromaticContact CD2-CE1 3.88Å; Y459-F548 HydrophobicContact CD2-CE1 3.88Å; Y459-F548 HydrophobicContact CD2-CZ 4.36Å; Y459-F548 HydrophobicContact CG-CE1 4.36Å; Y459-F548 CarbonylContact O-C 3.57Å; Y459-F548 WeakPolarHBondContact O-CA 3.35Å; Y459-S549 WeakPolarHBondContact O-CB 3.36Å; Y459-S549 PolarHBondContact O-N 3.37Å
460D98.1Very high98.1Very high18 Ų1840.5 Ų40.510%0.09622%0.224CC..  trans-123102.2164-178.2-7.7000108.8S462 R463 R468 V470D460-S462 VanDerWaalsContact CG-OG 3.31Å; D460-S462 PolarHBondContact O-N 2.63Å; D460-S462 VanDerWaalsContact OD1-CB 3.31Å; D460-S462 WeakPolarHBondContact OD1-CB 3.1Å; D460-S462 PolarHBondContact OD1-N 3.04Å; D460-S462 PolarHBondContact OD1-OG 2.05Å; D460-S462 PolarHBondContact OD2-OG 3.34Å; D460-R463 HydrophobicContact CB-CG 4.1Å; D460-R463 WeakPolarHBondContact O-CB 3.37Å; D460-R463 PolarHBondContact O-N 2.95Å; D460-R468 PolarHBondContact N-O 3.48Å; D460-V470 HydrophobicContact CB-CG1 3.56Å
461L96.6Very high98.1Very high53 Ų5345.5 Ų45.528%0.27725%0.246SC..THydrogen-bonded Turntrans-72.2-13.1-175.9-61.4178.4000113.3V439 Y442 R463 F548V439-L461 HydrophobicContact CB-CD2 4.24Å; Y442-L461 HydrophobicContact CD1-CD1 3.5Å; Y442-L461 HydrophobicContact CD1-CD2 4.23Å; Y442-L461 HydrophobicContact CE1-CD1 3.51Å; Y442-L461 HydrophobicContact CG-CD1 4.12Å; Y442-L461 HydrophobicContact CG-CD2 4.05Å; L461-R463 PolarHBondContact O-N 2.83Å; L461-F548 HydrophobicContact CD1-CD1 3.75Å; L461-F548 HydrophobicContact CD1-CE1 3.87Å; L461-F548 HydrophobicContact CD2-CD1 4.3Å; L461-F548 HydrophobicContact CD2-CE1 4.13Å; L461-F548 HydrophobicContact CG-CD1 3.85Å; L461-F548 HydrophobicContact CG-CE1 4.12Å
462S96.3Very high98.1Very high83 Ų8346.2 Ų46.258%0.5825%0.249SC*.THydrogen-bonded Turntrans-71.2-20.9174.375.10000112.3D460D460-S462 VanDerWaalsContact CG-OG 3.31Å; D460-S462 PolarHBondContact O-N 2.63Å; D460-S462 VanDerWaalsContact OD1-CB 3.31Å; D460-S462 WeakPolarHBondContact OD1-CB 3.1Å; D460-S462 PolarHBondContact OD1-N 3.04Å; D460-S462 PolarHBondContact OD1-OG 2.05Å; D460-S462 PolarHBondContact OD2-OG 3.34Å
463R97.4Very high98.1Very high102 Ų10247 Ų4739%0.38525%0.253SS..SBendtrans-76.1158175.9-59.3175.371.298.1-5.2110.9D460 L461 D467 R468D460-R463 HydrophobicContact CB-CG 4.1Å; D460-R463 WeakPolarHBondContact O-CB 3.37Å; D460-R463 PolarHBondContact O-N 2.95Å; L461-R463 PolarHBondContact O-N 2.83Å; R463-D467 WeakPolarHBondContact CB-O 3.42Å; R463-D467 WeakPolarHBondContact CD-O 3.39Å; R463-D467 IonicContact CZ-OD1 3.08Å; R463-D467 IonicContact CZ-OD2 3.86Å; R463-D467 VanDerWaalsContact CZ-OD2 3.28Å; R463-D467 PolarHBondContact NE-O 3.44Å; R463-D467 IonicContact NE-OD1 2.76Å; R463-D467 PolarHBondContact NE-OD1 3.4Å; R463-D467 IonicContact NE-OD2 3.8Å; R463-D467 PolarHBondContact NE-OD2 3.23Å; R463-D467 IonicContact NH2-OD1 3.85Å; R463-D467 PolarHBondContact NH2-OD1 2.86Å; R463-D467 IonicContact NH2-OD2 3.46Å; R463-D467 PolarHBondContact NH2-OD2 3.41Å; R463-R468 HydrophobicContact CB-CG 4.34Å; R463-R468 PolarHBondContact O-NE 3.16Å
464K97.4Very high98.1Very high172 Ų17247.1 Ų47.175%0.74825%0.254SS*.PPolyproline II helixtrans-65.4145.5178.9-65.9-177.1-179.6179.50110.1G466 D467K464-G466 PolarHBondContact O-N 3.34Å; K464-D467 PolarHBondContact O-N 3.34Å; K464-D467 VanDerWaalsContact O-N 3.08Å
465P97.6Very high98Very high79 Ų7948.4 Ų48.451%0.51326%0.259SS..THydrogen-bonded Turntrans-48.7136171-26.834.9000111.6H440H440-P465 HydrophobicContact CB-CB 4.26Å; H440-P465 WeakPolarHBondContact O-CG 3.35Å
466G97.1Very high97.8Very high52 Ų5249.3 Ų49.354%0.53627%0.265SS..THydrogen-bonded Turntrans93-8.7-17400000115.1K464K464-G466 PolarHBondContact O-N 3.34Å
467D98Very high97.4Very high79 Ų7948.1 Ų48.142%0.42226%0.263SS..SBendtrans-141.236.9177-179.431000111E436 R463 K464E436-D467 PolarHBondContact OE2-N 2.87Å; E436-D467 VanDerWaalsContact OE2-N 3.13Å; R463-D467 WeakPolarHBondContact CB-O 3.42Å; R463-D467 WeakPolarHBondContact CD-O 3.39Å; R463-D467 IonicContact CZ-OD1 3.08Å; R463-D467 IonicContact CZ-OD2 3.86Å; R463-D467 VanDerWaalsContact CZ-OD2 3.28Å; R463-D467 PolarHBondContact NE-O 3.44Å; R463-D467 IonicContact NE-OD1 2.76Å; R463-D467 PolarHBondContact NE-OD1 3.4Å; R463-D467 IonicContact NE-OD2 3.8Å; R463-D467 PolarHBondContact NE-OD2 3.23Å; R463-D467 IonicContact NH2-OD1 3.85Å; R463-D467 PolarHBondContact NH2-OD1 2.86Å; R463-D467 IonicContact NH2-OD2 3.46Å; R463-D467 PolarHBondContact NH2-OD2 3.41Å; K464-D467 PolarHBondContact O-N 3.34Å; K464-D467 VanDerWaalsContact O-N 3.08Å
468R98.3Very high97Very high37 Ų3755 Ų5514%0.1429%0.293CS..  trans-94-19.4-178.9-71-176.5167167.7-1.9113.3E436 V439 H440 Y459 D460 R463 V470E436-R468 VanDerWaalsContact CD-N 3.35Å; E436-R468 PolarHBondContact OE1-N 3.11Å; E436-R468 PolarHBondContact OE2-N 2.91Å; V439-R468 HydrophobicContact CG2-CB 3.75Å; V439-R468 HydrophobicContact CG2-CG 4.49Å; V439-R468 PolarHBondContact O-NH1 3.25Å; H440-R468 PolarHBondContact O-NH1 2.85Å; H440-R468 VanDerWaalsContact O-NH1 3.08Å; Y459-R468 CarbonylContact C-O 3.54Å; Y459-R468 VanDerWaalsContact CA-O 3.25Å; Y459-R468 WeakPolarHBondContact CA-O 3.15Å; D460-R468 PolarHBondContact N-O 3.48Å; R463-R468 HydrophobicContact CB-CG 4.34Å; R463-R468 PolarHBondContact O-NE 3.16Å; R468-V470 PolarHBondContact O-N 2.84Å
469V98.4Very high96.6Very high4 Ų454.9 Ų54.92%0.02429%0.292CS..EExtended strand (participates in β ladder)trans-82.1107.7-180-179.20000109.1K432 F435 E436 V457 Y459 L472K432-V469 HydrophobicContact CD-CB 4.1Å; K432-V469 HydrophobicContact CD-CG1 4Å; K432-V469 VanDerWaalsContact NZ-CB 3.27Å; K432-V469 PolarHBondContact NZ-O 3.48Å; F435-V469 HydrophobicContact CB-CG2 3.76Å; E436-V469 HydrophobicContact CG-CG2 4.04Å; E436-V469 VanDerWaalsContact OE1-CB 3.22Å; E436-V469 WeakPolarHBondContact OE1-CB 3.02Å; E436-V469 WeakPolarHBondContact OE1-CG2 3.47Å; E436-V469 PolarHBondContact OE1-N 3.44Å; V457-V469 HydrophobicContact CG2-CG1 4.01Å; Y459-V469 HydrophobicContact CD1-CB 4.5Å; Y459-V469 HydrophobicContact CD1-CG2 3.84Å; Y459-V469 HydrophobicContact CE1-CG2 3.62Å; V469-L472 HydrophobicContact CG1-CB 4.01Å; V469-L472 HydrophobicContact CG1-CD2 4.43Å
470V98Very high96.2Very high68 Ų6866.3 Ų66.341%0.41234%0.336SS..EExtended strand (participates in β ladder)trans-91.3-24.6-180-63.30000113.2V458 D460 R468V458-V470 HydrophobicContact CB-CG2 3.85Å; V458-V470 HydrophobicContact CG1-CG2 3.64Å; V458-V470 VanDerWaalsContact O-CG2 3.24Å; V458-V470 WeakPolarHBondContact O-CG2 3.12Å; V458-V470 PolarHBondContact O-N 2.81Å; D460-V470 HydrophobicContact CB-CG1 3.56Å; R468-V470 PolarHBondContact O-N 2.84Å
471K98.4Very high96Very high106 Ų10670.9 Ų70.946%0.46136%0.364SS..EExtended strand (participates in β ladder)trans-146.9141175.3-166.5178-173.2-1460110.3V457 V458 D473V457-K471 WeakPolarHBondContact CA-O 3.24Å; V458-K471 HydrophobicContact CB-CB 3.85Å; V458-K471 HydrophobicContact CG2-CB 3.86Å; V458-K471 HydrophobicContact CG2-CD 4.34Å; V458-K471 PolarHBondContact N-O 3.04Å; V458-K471 PolarHBondContact O-N 3.32Å; K471-D473 VanDerWaalsContact CE-CG 3.48Å; K471-D473 WeakPolarHBondContact CE-OD1 3.34Å; K471-D473 WeakPolarHBondContact CE-OD2 3.34Å; K471-D473 IonicContact NZ-OD1 3.67Å; K471-D473 IonicContact NZ-OD2 3.8Å; K471-D473 PolarHBondContact NZ-OD2 3.48Å
472L98.7Very high95.9Very high14 Ų1471 Ų717%0.07337%0.368CS..EExtended strand (participates in β ladder)trans-148.998.3177.3-173.356.4000108.8K432 F435 I455 H456 V457 V469 L487K432-L472 HydrophobicContact CD-CD2 4.24Å; F435-L472 HydrophobicContact CB-CD2 4.32Å; F435-L472 HydrophobicContact CD2-CD1 3.77Å; F435-L472 HydrophobicContact CD2-CD2 3.51Å; F435-L472 HydrophobicContact CD2-CG 4.3Å; F435-L472 HydrophobicContact CE2-CD1 3.79Å; F435-L472 HydrophobicContact CE2-CD2 4.15Å; F435-L472 HydrophobicContact CG-CD1 4.17Å; F435-L472 HydrophobicContact CG-CD2 4.11Å; F435-L472 HydrophobicContact CZ-CD1 4.19Å; I455-L472 HydrophobicContact CG2-CD1 3.5Å; I455-L472 VanDerWaalsContact CG2-CD1 3.5Å; H456-L472 WeakPolarHBondContact O-CA 3.41Å; V457-L472 HydrophobicContact CB-CD1 3.77Å; V457-L472 HydrophobicContact CG2-CD1 3.88Å; V469-L472 HydrophobicContact CG1-CB 4.01Å; V469-L472 HydrophobicContact CG1-CD2 4.43Å; L472-L487 HydrophobicContact CB-CB 4.47Å; L472-L487 HydrophobicContact CD2-CD2 3.48Å; L472-L487 VanDerWaalsContact CD2-CD2 3.48Å; L472-L487 HydrophobicContact CG-CB 4.23Å; L472-L487 HydrophobicContact CG-CD2 4.06Å; L472-L487 VanDerWaalsContact O-CB 3.29Å; L472-L487 WeakPolarHBondContact O-CB 3.15Å; L472-L487 PolarHBondContact O-N 3.36Å
473D98.8Very high95.9Very high16 Ų1669.6 Ų69.69%0.08636%0.358CS..EExtended strand (participates in β ladder)trans-103.5146.9175.7-54.5-33.5000109.8I455 H456 K471 Y484 D485I455-D473 WeakPolarHBondContact CA-O 3.31Å; H456-D473 HydrophobicContact CB-CB 4.4Å; H456-D473 PolarHBondContact N-O 3.31Å; H456-D473 PolarHBondContact O-N 2.85Å; K471-D473 VanDerWaalsContact CE-CG 3.48Å; K471-D473 WeakPolarHBondContact CE-OD1 3.34Å; K471-D473 WeakPolarHBondContact CE-OD2 3.34Å; K471-D473 IonicContact NZ-OD1 3.67Å; K471-D473 IonicContact NZ-OD2 3.8Å; K471-D473 PolarHBondContact NZ-OD2 3.48Å; D473-Y484 HydrophobicContact CB-CD1 4.14Å; D473-D485 CarbonylContact C-O 3.6Å; D473-D485 VanDerWaalsContact CA-O 3.3Å; D473-D485 WeakPolarHBondContact CA-O 3.26Å
474V98.6Very high95.9Very high4 Ų468.6 Ų68.62%0.02436%0.355CS..EExtended strand (participates in β ladder)trans-132.3148.8-177.2-60.30000110.7M386 I455 C476 Y484 D485 L487 Y493M386-V474 HydrophobicContact CE-CB 3.95Å; M386-V474 HydrophobicContact CE-CG1 3.45Å; M386-V474 VanDerWaalsContact CE-CG1 3.45Å; M386-V474 HydrophobicContact CG-CB 4.41Å; M386-V474 HydrophobicContact SD-CB 3.73Å; M386-V474 HydrophobicContact SD-CG1 3.96Å; M386-V474 HydrophobicContact SD-CG2 4.31Å; I455-V474 HydrophobicContact CG1-CG1 4.26Å; I455-V474 HydrophobicContact CG2-CG1 4.41Å; V474-C476 PolarHBondContact O-N 3.13Å; V474-Y484 WeakPolarHBondContact O-CA 3.48Å; V474-D485 PolarHBondContact N-O 3.31Å; V474-D485 PolarHBondContact O-N 2.97Å; V474-L487 HydrophobicContact CG1-CB 4.37Å; V474-L487 HydrophobicContact CG1-CD1 3.81Å; V474-L487 HydrophobicContact CG2-CD1 4.15Å; V474-Y493 HydrophobicContact CG2-CD1 4.13Å; V474-Y493 HydrophobicContact CG2-CE1 3.58Å
475L97.2Very high96Very high33 Ų3364.1 Ų64.117%0.17334%0.339CS..EExtended strand (participates in β ladder)trans-72.7118.4-179.1-16371.7000110W381 S385 G454 P482 S483 Y484W381-L475 HydrophobicContact CH2-CD2 4.1Å; W381-L475 HydrophobicContact CZ2-CD2 3.79Å; W381-L475 HydrophobicContact CZ2-CG 4.31Å; S385-L475 PolarHBondContact OG-O 3.18Å; G454-L475 WeakPolarHBondContact O-CB 3.5Å; G454-L475 PolarHBondContact O-N 2.89Å; L475-P482 HydrophobicContact CD1-CB 3.84Å; L475-P482 HydrophobicContact CD2-CB 3.95Å; L475-P482 HydrophobicContact CG-CB 3.87Å; L475-S483 WeakPolarHBondContact CA-O 3.4Å; L475-Y484 HydrophobicContact CB-CE1 4.44Å; L475-Y484 HydrophobicContact CD1-CD2 4.08Å; L475-Y484 HydrophobicContact CD1-CE2 3.93Å
476C94.6Very high96Very high19 Ų1964.5 Ų64.513%0.12834%0.342CS..  trans-57.6142.4179.363.50000110.8W381 V474 C479 S483W381-C476 PolarHBondContact NE1-O 3.19Å; V474-C476 PolarHBondContact O-N 3.13Å; C476-C479 HydrophobicContact CB-CB 3.99Å; C476-C479 WeakPolarHBondContact CB-SG 3.41Å; C476-C479 PolarHBondContact O-SG 3.46Å; C476-C479 WeakPolarHBondContact SG-CB 3.25Å; C476-C479 CovalentContact SG-SG 2.04Å; C476-C479 PolarHBondContact SG-SG 3.08Å; C476-S483 PolarHBondContact N-O 2.64Å; C476-S483 PolarHBondContact SG-N 3.19Å; C476-S483 PolarHBondContact SG-O 3.13Å
477T89.9Confident96.1Very high37 Ų3763.1 Ų63.123%0.22732%0.322CS..SBendtrans-101.8-37.6169.252.60000111.6F380 W381 N382 S385 C479F380-T477 WeakPolarHBondContact CA-O 3.5Å; W381-T477 PolarHBondContact N-O 3.44Å; N382-T477 WeakPolarHBondContact O-CB 3.49Å; S385-T477 VanDerWaalsContact OG-CG2 3.26Å; S385-T477 WeakPolarHBondContact OG-CG2 3.48Å; T477-C479 PolarHBondContact O-N 3.38Å
478K90.8Very high96.1Very high147 Ų14764.8 Ų64.864%0.63933%0.325SS*.SBendtrans-81.858178.3-161.7179.1179.1177.40111.9M379 F380M379-K478 WeakPolarHBondContact O-CA 3.44Å; F380-K478 HydrophobicContact CD1-CB 4Å; F380-K478 HydrophobicContact CD1-CG 4.47Å; F380-K478 HydrophobicContact CE1-CB 3.57Å; F380-K478 HydrophobicContact CE1-CD 4.47Å; F380-K478 HydrophobicContact CE1-CG 3.99Å; F380-K478 HydrophobicContact CZ-CB 4.16Å; F380-K478 HydrophobicContact CZ-CD 4.22Å; F380-K478 HydrophobicContact CZ-CG 4.08Å
479C90.7Very high96.1Very high29 Ų2967.3 Ų67.320%0.19634%0.34CS..SBendtrans-153.4155.2-176.8550000109.5W381 C476 T477W381-C479 VanDerWaalsContact CD1-O 3.25Å; C476-C479 HydrophobicContact CB-CB 3.99Å; C476-C479 WeakPolarHBondContact CB-SG 3.41Å; C476-C479 PolarHBondContact O-SG 3.46Å; C476-C479 WeakPolarHBondContact SG-CB 3.25Å; C476-C479 CovalentContact SG-SG 2.04Å; C476-C479 PolarHBondContact SG-SG 3.08Å; T477-C479 PolarHBondContact O-N 3.38Å
480R89.1Confident96.1Very high240 Ų24074 Ų7491%0.90638%0.376SS*.SBendtrans-81.9-33.1176-69.5-172.772-155.52.7112.7
481V93.2Very high96.1Very high114 Ų11474.8 Ų74.869%0.69138%0.375SS*.SBendtrans-116.9116.2176.8-179.30000106.8S483V481-S483 PolarHBondContact O-N 3.44Å
482P95.2Very high96Very high57 Ų5774.3 Ų74.337%0.3738%0.376SS..  trans-60.7125.9179-19.529.8000111.3W381 L475W381-P482 HydrophobicContact CD2-CG 3.73Å; W381-P482 HydrophobicContact CE3-CG 4.31Å; W381-P482 HydrophobicContact CG-CG 3.99Å; W381-P482 HydrophobicContact CZ2-CB 3.99Å; W381-P482 HydrophobicContact CZ2-CG 3.97Å; L475-P482 HydrophobicContact CD1-CB 3.84Å; L475-P482 HydrophobicContact CD2-CB 3.95Å; L475-P482 HydrophobicContact CG-CB 3.87Å
483S96.8Very high95.9Very high53 Ų5374.9 Ų74.937%0.37138%0.378SS..  trans-138.6157.9177.256.60000110.6L475 C476 V481L475-S483 WeakPolarHBondContact CA-O 3.4Å; C476-S483 PolarHBondContact N-O 2.64Å; C476-S483 PolarHBondContact SG-N 3.19Å; C476-S483 PolarHBondContact SG-O 3.13Å; V481-S483 PolarHBondContact O-N 3.44Å
484Y98.3Very high95.7Very high80 Ų8077.6 Ų77.631%0.31439%0.389SS..EExtended strand (participates in β ladder)trans-84.3119.3175.6-77.1-85000110.7H456 D473 V474 L475H456-Y484 HydrophobicContact CB-CD1 4.23Å; H456-Y484 HydrophobicContact CB-CE1 4.22Å; H456-Y484 AromaticContact CD2-CE1 3.67Å; H456-Y484 AromaticContact CD2-CZ 3.59Å; H456-Y484 AromaticContact CE1-CD2 3.7Å; H456-Y484 AromaticContact CE1-CE1 3.97Å; H456-Y484 AromaticContact CE1-CE2 3.33Å; H456-Y484 WeakPolarHBondContact CE1-CE2 3.03Å; H456-Y484 AromaticContact CE1-CZ 3.48Å; H456-Y484 VanDerWaalsContact CE1-CZ 3.48Å; H456-Y484 AromaticContact CG-CD1 3.89Å; H456-Y484 AromaticContact CG-CE1 3.64Å; H456-Y484 AromaticContact CG-CZ 3.9Å; H456-Y484 AromaticContact ND1-CD1 3.82Å; H456-Y484 AromaticContact ND1-CD2 3.84Å; H456-Y484 AromaticContact ND1-CE1 3.82Å; H456-Y484 AromaticContact ND1-CE2 3.83Å; H456-Y484 AromaticContact ND1-CG 3.82Å; H456-Y484 AromaticContact ND1-CZ 3.82Å; H456-Y484 AromaticContact NE2-CE1 3.91Å; H456-Y484 AromaticContact NE2-CE2 3.62Å; H456-Y484 AromaticContact NE2-CZ 3.33Å; H456-Y484 VanDerWaalsContact NE2-CZ 3.33Å; H456-Y484 PolarHBondContact NE2-OH 3.4Å; D473-Y484 HydrophobicContact CB-CD1 4.14Å; V474-Y484 WeakPolarHBondContact O-CA 3.48Å; L475-Y484 HydrophobicContact CB-CE1 4.44Å; L475-Y484 HydrophobicContact CD1-CD2 4.08Å; L475-Y484 HydrophobicContact CD1-CE2 3.93Å
485D97.8Very high95.7Very high78 Ų7877.4 Ų77.442%0.41739%0.388SS..EExtended strand (participates in β ladder)trans-116.9151173.2-67-45.9000110.1D473 V474 L487D473-D485 CarbonylContact C-O 3.6Å; D473-D485 VanDerWaalsContact CA-O 3.3Å; D473-D485 WeakPolarHBondContact CA-O 3.26Å; V474-D485 PolarHBondContact N-O 3.31Å; V474-D485 PolarHBondContact O-N 2.97Å; D485-L487 PolarHBondContact O-N 2.82Å
486P98.5Very high95.7Very high87 Ų8775.9 Ų75.957%0.56538%0.379SS*.EExtended strand (participates in β ladder)trans-57.1135.7175.2-24.934.6000112K488P486-K488 PolarHBondContact O-N 2.99Å
487L98.5Very high95.9Very high23 Ų2375 Ų7512%0.1237%0.373CS..PPolyproline II helixtrans-59.2128.6173.5-175.780.2000110.3G428 L431 K432 L472 V474 D485 Y493G428-L487 VanDerWaalsContact O-CD2 3.32Å; G428-L487 WeakPolarHBondContact O-CD2 3.47Å; L431-L487 HydrophobicContact CB-CD2 4.16Å; L431-L487 HydrophobicContact CD1-CD1 4.14Å; K432-L487 HydrophobicContact CB-CD2 4.39Å; L472-L487 HydrophobicContact CB-CB 4.47Å; L472-L487 HydrophobicContact CD2-CD2 3.48Å; L472-L487 VanDerWaalsContact CD2-CD2 3.48Å; L472-L487 HydrophobicContact CG-CB 4.23Å; L472-L487 HydrophobicContact CG-CD2 4.06Å; L472-L487 VanDerWaalsContact O-CB 3.29Å; L472-L487 WeakPolarHBondContact O-CB 3.15Å; L472-L487 PolarHBondContact O-N 3.36Å; V474-L487 HydrophobicContact CG1-CB 4.37Å; V474-L487 HydrophobicContact CG1-CD1 3.81Å; V474-L487 HydrophobicContact CG2-CD1 4.15Å; D485-L487 PolarHBondContact O-N 2.82Å; L487-Y493 HydrophobicContact CD1-CD1 4.38Å; L487-Y493 HydrophobicContact CD1-CD2 3.7Å; L487-Y493 HydrophobicContact CD1-CE1 4.1Å; L487-Y493 HydrophobicContact CD1-CE2 3.34Å; L487-Y493 HydrophobicContact CD1-CG 4.2Å; L487-Y493 HydrophobicContact CG-CE2 4.2Å
488K98.5Very high96.2Very high114 Ų11473.8 Ų73.850%0.49637%0.366SS..PPolyproline II helixtrans-101.4129.2175.9-66.4167-176.8177.50110.1G428 P486 D490 E491 Y493G428-K488 WeakPolarHBondContact CA-O 3.18Å; P486-K488 PolarHBondContact O-N 2.99Å; K488-D490 VanDerWaalsContact C-N 3.32Å; K488-D490 PolarHBondContact O-N 2.89Å; K488-E491 HydrophobicContact CB-CB 4.11Å; K488-E491 HydrophobicContact CB-CG 3.91Å; K488-E491 HydrophobicContact CD-CG 3.94Å; K488-E491 WeakPolarHBondContact CD-OE1 3.5Å; K488-E491 IonicContact NZ-OE1 3.92Å; K488-E491 PolarHBondContact NZ-OE1 2.9Å; K488-E491 PolarHBondContact O-N 2.79Å; K488-Y493 PolarHBondContact N-OH 3.12Å; K488-Y493 WeakPolarHBondContact O-CE2 3.22Å
489M98.4Very high96.1Very high91 Ų9169 Ų6945%0.44835%0.348SS..THydrogen-bonded Turntrans-61.2-38.2-170.3-61.2-61.5-83.100113.5G428 S429 K432G428-M489 CarbonylContact C-O 3.59Å; G428-M489 PolarHBondContact N-O 2.66Å; S429-M489 PolarHBondContact N-O 2.91Å; K432-M489 HydrophobicContact CB-CE 4.07Å; K432-M489 HydrophobicContact CB-SD 4.07Å; K432-M489 HydrophobicContact CG-CE 4.17Å; K432-M489 HydrophobicContact CG-SD 4.35Å
490D97.8Very high96.2Very high144 Ų14470.5 Ų70.577%0.7735%0.351SS*.THydrogen-bonded Turntrans-91.6-8.7-175.2-59.8-48.4000113.9K488K488-D490 VanDerWaalsContact C-N 3.32Å; K488-D490 PolarHBondContact O-N 2.89Å
491E97.7Very high96.6Very high85 Ų8559.1 Ų59.140%0.39731%0.308SS..SBendtrans-78.2152.4175.5-72.5-167.7-175.100111.3K427 G428 K488 Y493K427-E491 CarbonylContact C-O 3.4Å; K427-E491 WeakPolarHBondContact CA-O 3.48Å; G428-E491 PolarHBondContact N-O 2.91Å; K488-E491 HydrophobicContact CB-CB 4.11Å; K488-E491 HydrophobicContact CB-CG 3.91Å; K488-E491 HydrophobicContact CD-CG 3.94Å; K488-E491 WeakPolarHBondContact CD-OE1 3.5Å; K488-E491 IonicContact NZ-OE1 3.92Å; K488-E491 PolarHBondContact NZ-OE1 2.9Å; K488-E491 PolarHBondContact O-N 2.79Å; E491-Y493 HydrophobicContact CB-CE2 3.75Å; E491-Y493 WeakPolarHBondContact O-CD2 3.37Å; E491-Y493 PolarHBondContact OE2-OH 2.86Å
492I97.1Very high96.5Very high95 Ų9553.7 Ų53.749%0.48728%0.275SS..EExtended strand (participates in β ladder)trans-100.3128.2178.5-61169.1000108.6Q425 L426 L516Q425-I492 HydrophobicContact CB-CG2 4.03Å; L426-I492 WeakPolarHBondContact O-CA 3.44Å; I492-L516 HydrophobicContact CD1-CD1 3.54Å; I492-L516 HydrophobicContact CG1-CD1 3.74Å; I492-L516 HydrophobicContact CG2-CD1 4.08Å
493Y96.8Very high96.1Very high27 Ų2755.1 Ų55.111%0.10628%0.28CS..EExtended strand (participates in β ladder)trans-115144.6179.2-61.9-87.7000110M386 Q425 L426 L431 V474 L487 K488 E491M386-Y493 HydrophobicContact SD-CD1 3.88Å; M386-Y493 HydrophobicContact SD-CG 4.32Å; Q425-Y493 WeakPolarHBondContact CA-O 3.47Å; L426-Y493 PolarHBondContact N-O 3.09Å; L426-Y493 PolarHBondContact O-N 2.64Å; L431-Y493 HydrophobicContact CD1-CD2 4.05Å; L431-Y493 HydrophobicContact CD1-CG 4.05Å; V474-Y493 HydrophobicContact CG2-CD1 4.13Å; V474-Y493 HydrophobicContact CG2-CE1 3.58Å; L487-Y493 HydrophobicContact CD1-CD1 4.38Å; L487-Y493 HydrophobicContact CD1-CD2 3.7Å; L487-Y493 HydrophobicContact CD1-CE1 4.1Å; L487-Y493 HydrophobicContact CD1-CE2 3.34Å; L487-Y493 HydrophobicContact CD1-CG 4.2Å; L487-Y493 HydrophobicContact CG-CE2 4.2Å; K488-Y493 PolarHBondContact N-OH 3.12Å; K488-Y493 WeakPolarHBondContact O-CE2 3.22Å; E491-Y493 HydrophobicContact CB-CE2 3.75Å; E491-Y493 WeakPolarHBondContact O-CD2 3.37Å; E491-Y493 PolarHBondContact OE2-OH 2.86Å
494K94.8Very high95.9Very high73 Ų7352.8 Ų52.832%0.31726%0.264SS..EExtended strand (participates in β ladder)trans-96.7124170.3-75.2167.2179.1179.30108.2H383 V384 L423 V424 Q425H383-K494 WeakPolarHBondContact O-CD 3.49Å; V384-K494 HydrophobicContact CG1-CB 4.4Å; V384-K494 HydrophobicContact CG2-CB 4.07Å; V384-K494 HydrophobicContact CG2-CD 4.46Å; L423-K494 HydrophobicContact CD1-CB 4.18Å; V424-K494 WeakPolarHBondContact O-CA 3.34Å; Q425-K494 HydrophobicContact CG-CG 3.82Å
495V97.9Very high95.4Very high0 Ų049.2 Ų49.20%025%0.252CS..EExtended strand (participates in β ladder)trans-130.7136.2-175.2-1750000109.6M386 I388 V424 L431M386-V495 HydrophobicContact CB-CG1 4.41Å; M386-V495 HydrophobicContact CB-CG2 4.14Å; M386-V495 HydrophobicContact CE-CG2 3.84Å; M386-V495 HydrophobicContact SD-CG2 4.38Å; I388-V495 HydrophobicContact CD1-CG1 4.34Å; I388-V495 HydrophobicContact CG1-CG1 3.93Å; I388-V495 HydrophobicContact CG2-CG1 4.24Å; V424-V495 HydrophobicContact CG2-CB 4.37Å; V424-V495 WeakPolarHBondContact CG2-O 3.44Å; V424-V495 PolarHBondContact N-O 3.21Å; V424-V495 PolarHBondContact O-N 3.35Å; L431-V495 HydrophobicContact CD1-CG2 3.88Å; L431-V495 HydrophobicContact CD2-CG2 3.85Å; L431-V495 HydrophobicContact CG-CG2 4.42Å
496I97.4Very high95.2Very high0 Ų046.3 Ų46.30%024%0.236CC..EExtended strand (participates in β ladder)trans-92.8132.1172.9-42.2170.8000108.1M368 I369 N372 V384 M386 C387 I388 F421 D422 L423M368-I496 HydrophobicContact CB-CB 4.49Å; M368-I496 HydrophobicContact CB-CD1 4.48Å; M368-I496 HydrophobicContact CB-CG2 4.08Å; M368-I496 HydrophobicContact CE-CB 4.03Å; M368-I496 HydrophobicContact CE-CG2 3.61Å; M368-I496 VanDerWaalsContact O-CD1 3.3Å; M368-I496 WeakPolarHBondContact O-CD1 3.26Å; I369-I496 HydrophobicContact CG1-CD1 4.3Å; N372-I496 HydrophobicContact CB-CD1 3.54Å; V384-I496 HydrophobicContact CB-CD1 4.47Å; V384-I496 HydrophobicContact CB-CG1 4.49Å; V384-I496 HydrophobicContact CG1-CD1 3.77Å; V384-I496 HydrophobicContact CG1-CG1 3.45Å; V384-I496 VanDerWaalsContact CG1-CG1 3.45Å; M386-I496 PolarHBondContact O-N 2.64Å; C387-I496 VanDerWaalsContact CA-O 3.28Å; C387-I496 WeakPolarHBondContact CA-O 3.04Å; I388-I496 PolarHBondContact N-O 3.12Å; F421-I496 HydrophobicContact CB-CG2 4.12Å; D422-I496 VanDerWaalsContact O-CA 3.29Å; D422-I496 WeakPolarHBondContact O-CA 3.13Å; D422-I496 WeakPolarHBondContact O-CG2 3.49Å; L423-I496 HydrophobicContact CD1-CG1 4.29Å
497L98.1Very high95Very high0 Ų043.7 Ų43.70%023%0.225CC..EExtended strand (participates in β ladder)trans-152.8160-179.873.1175.9000111I388 F421 D422 V424 L501 I511I388-L497 HydrophobicContact CD1-CB 4.37Å; I388-L497 HydrophobicContact CD1-CD1 4.22Å; I388-L497 HydrophobicContact CG1-CB 3.68Å; I388-L497 HydrophobicContact CG1-CD1 4.43Å; I388-L497 WeakPolarHBondContact O-CA 3.29Å; F421-L497 CarbonylContact C-O 3.6Å; D422-L497 PolarHBondContact N-O 3.23Å; D422-L497 PolarHBondContact O-N 3.37Å; V424-L497 HydrophobicContact CB-CD2 4.04Å; V424-L497 HydrophobicContact CG1-CD2 3.63Å; V424-L497 HydrophobicContact CG2-CD1 4.32Å; V424-L497 HydrophobicContact CG2-CD2 3.34Å; V424-L497 HydrophobicContact CG2-CG 4.5Å; L497-L501 HydrophobicContact CD1-CB 3.7Å; L497-L501 HydrophobicContact CG-CB 4.25Å; L497-I511 HydrophobicContact CD1-CD1 3.88Å; L497-I511 HydrophobicContact CD1-CG2 3.92Å
498P97.4Very high94.9Very high12 Ų1242.6 Ų42.68%0.07822%0.22CC..EExtended strand (participates in β ladder)trans-56.4141.5170.9-22.432.1000112I388 L389 T420 F421 F500 L501 A502I388-P498 WeakPolarHBondContact O-CD 3.31Å; L389-P498 HydrophobicContact CD1-CG 3.47Å; L389-P498 VanDerWaalsContact CD1-CG 3.47Å; T420-P498 CarbonylContact O-C 3.55Å; T420-P498 WeakPolarHBondContact O-CA 3.45Å; F421-P498 HydrophobicContact CD1-CB 4.49Å; F421-P498 HydrophobicContact CD1-CG 4.27Å; F421-P498 HydrophobicContact CE1-CG 4.2Å; P498-F500 HydrophobicContact CB-CB 4.34Å; P498-F500 PolarHBondContact O-N 2.94Å; P498-F500 VanDerWaalsContact O-N 3.11Å; P498-L501 PolarHBondContact O-N 2.86Å; P498-A502 PolarHBondContact O-N 2.04Å; P498-A502 VanDerWaalsContact O-N 3.17Å
499N89.1Confident94.8Very high47 Ų4740.5 Ų40.525%0.25121%0.212SC..Hα-helixtrans-54-30.7172.670.6-29.6000112.6T420 D422 L501 A502 N503T420-N499 PolarHBondContact N-OD1 2.92Å; T420-N499 PolarHBondContact O-N 3.43Å; T420-N499 WeakPolarHBondContact OG1-CB 3.14Å; D422-N499 WeakPolarHBondContact OD2-CB 3.38Å; N499-L501 VanDerWaalsContact C-N 3.34Å; N499-L501 PolarHBondContact O-N 2.86Å; N499-A502 PolarHBondContact O-N 3.18Å; N499-N503 WeakPolarHBondContact O-CB 3.39Å; N499-N503 VanDerWaalsContact O-CG 3.32Å; N499-N503 PolarHBondContact O-N 3.29Å; N499-N503 PolarHBondContact O-ND2 2.9Å
500F92.1Very high94.8Very high61 Ų6137.6 Ų37.627%0.26820%0.197SC..Hα-helixtrans-53.2-48.2171.5176-104.5000112.2F183 P498 N503 G504 G505 D506F183-F500 WeakPolarHBondContact O-CE2 3.3Å; F183-F500 WeakPolarHBondContact O-CZ 3.32Å; P498-F500 HydrophobicContact CB-CB 4.34Å; P498-F500 PolarHBondContact O-N 2.94Å; P498-F500 VanDerWaalsContact O-N 3.11Å; F500-N503 PolarHBondContact O-N 2.95Å; F500-G504 PolarHBondContact O-N 2.69Å; F500-G505 VanDerWaalsContact CZ-CA 3.5Å; F500-G505 WeakPolarHBondContact O-CA 3.29Å; F500-G505 PolarHBondContact O-N 2.91Å; F500-D506 HydrophobicContact CE1-CB 3.85Å; F500-D506 HydrophobicContact CZ-CB 4.33Å; F500-D506 VanDerWaalsContact CZ-N 3.27Å
501L96.7Very high94.7Very high0 Ų030.7 Ų30.70%016%0.16CC..Hα-helixtrans-71.7-38.6177.4-64.7-170.8000112.3N390 L450 L497 P498 N499 N503 G504 D506 F508 I511N390-L501 HydrophobicContact CB-CD1 4.06Å; N390-L501 HydrophobicContact CB-CD2 3.93Å; N390-L501 HydrophobicContact CB-CG 4.36Å; L450-L501 HydrophobicContact CD2-CD1 3.93Å; L497-L501 HydrophobicContact CD1-CB 3.7Å; L497-L501 HydrophobicContact CG-CB 4.25Å; P498-L501 PolarHBondContact O-N 2.86Å; N499-L501 VanDerWaalsContact C-N 3.34Å; N499-L501 PolarHBondContact O-N 2.86Å; L501-N503 PolarHBondContact O-N 2.71Å; L501-G504 PolarHBondContact O-N 2.71Å; L501-D506 HydrophobicContact CD2-CB 4.43Å; L501-F508 HydrophobicContact CD2-CB 4.46Å; L501-F508 HydrophobicContact CD2-CD2 3.46Å; L501-F508 VanDerWaalsContact CD2-CD2 3.46Å; L501-F508 HydrophobicContact CD2-CE2 3.81Å; L501-F508 HydrophobicContact CD2-CG 4.09Å; L501-I511 HydrophobicContact CB-CD1 4.48Å
502A91.6Very high94.5Very high1 Ų131.7 Ų31.71%0.00816%0.163CC..Hα-helixtrans-58.5-3417500000111.9V424 P498 N499 G504V424-A502 HydrophobicContact CG1-CB 4.22Å; P498-A502 PolarHBondContact O-N 2.04Å; P498-A502 VanDerWaalsContact O-N 3.17Å; N499-A502 PolarHBondContact O-N 3.18Å; A502-G504 VanDerWaalsContact C-N 3.3Å; A502-G504 PolarHBondContact O-N 2.62Å
503N87.9Confident94.5Very high87 Ų8732.4 Ų32.447%0.46517%0.168SC..THydrogen-bonded Turntrans-86.49.1177.2-69.3-45.1000114.4N499 F500 L501 K512N499-N503 WeakPolarHBondContact O-CB 3.39Å; N499-N503 VanDerWaalsContact O-CG 3.32Å; N499-N503 PolarHBondContact O-N 3.29Å; N499-N503 PolarHBondContact O-ND2 2.9Å; F500-N503 PolarHBondContact O-N 2.95Å; L501-N503 PolarHBondContact O-N 2.71Å; N503-K512 WeakPolarHBondContact O-CD 3.44Å
504G91.6Very high94.5Very high3 Ų334 Ų343%0.03118%0.177CC..THydrogen-bonded Turntrans82.413.6176.200000115.1F500 L501 A502 G507 F508F500-G504 PolarHBondContact O-N 2.69Å; L501-G504 PolarHBondContact O-N 2.71Å; A502-G504 VanDerWaalsContact C-N 3.3Å; A502-G504 PolarHBondContact O-N 2.62Å; G504-G507 PolarHBondContact O-N 2.7Å; G504-F508 PolarHBondContact O-N 2.98Å
505G88.3Confident94.4Very high6 Ų632.8 Ų32.86%0.06217%0.173CC..G310 helixtrans-57159.4173.300000112.5F500 G507 F508F500-G505 VanDerWaalsContact CZ-CA 3.5Å; F500-G505 WeakPolarHBondContact O-CA 3.29Å; F500-G505 PolarHBondContact O-N 2.91Å; G505-G507 PolarHBondContact O-N 3.49Å; G505-F508 WeakPolarHBondContact O-CB 3.33Å; G505-F508 WeakPolarHBondContact O-CD2 3.44Å; G505-F508 PolarHBondContact O-N 2.97Å
506D93Very high94.2Very high16 Ų1637.1 Ų37.19%0.08620%0.196CC..G310 helixtrans53.920.8-173.2-85.7-12.9000113.9N390 H437 G447 E448 F500 L501 F508N390-D506 PolarHBondContact ND2-OD2 3.33Å; H437-D506 PolarHBondContact NE2-O 3.24Å; G447-D506 VanDerWaalsContact C-OD2 3.29Å; E448-D506 HydrophobicContact CB-CB 4.26Å; F500-D506 HydrophobicContact CE1-CB 3.85Å; F500-D506 HydrophobicContact CZ-CB 4.33Å; F500-D506 VanDerWaalsContact CZ-N 3.27Å; L501-D506 HydrophobicContact CD2-CB 4.43Å; D506-F508 VanDerWaalsContact C-N 3.33Å; D506-F508 HydrophobicContact CB-CD2 3.82Å; D506-F508 HydrophobicContact CB-CE2 3.95Å
507G93.5Very high93.5Very high33 Ų3343.1 Ų43.134%0.3422%0.219SC..G310 helixtrans77.214.3-178.300000114.5G504 G505 Q509G504-G507 PolarHBondContact O-N 2.7Å; G505-G507 PolarHBondContact O-N 3.49Å; G507-Q509 PolarHBondContact O-N 3.45Å
508F97.5Very high93.2Very high0 Ų046.1 Ų46.10%023%0.232CC..  trans-74.344.8174.2-74.6-90.5000113A434 H437 E448 L450 L501 G504 G505 D506 M510 I511A434-F508 HydrophobicContact CB-CD1 4Å; A434-F508 HydrophobicContact CB-CE1 4Å; A434-F508 WeakPolarHBondContact O-CE1 3.48Å; H437-F508 HydrophobicContact CB-CE1 4.43Å; H437-F508 AromaticContact CD2-CD1 3.82Å; H437-F508 AromaticContact CD2-CD2 3.81Å; H437-F508 AromaticContact CD2-CE1 3.7Å; H437-F508 AromaticContact CD2-CE2 3.73Å; H437-F508 AromaticContact CD2-CG 3.9Å; H437-F508 AromaticContact CD2-CZ 3.67Å; E448-F508 HydrophobicContact CB-CE2 3.64Å; E448-F508 HydrophobicContact CB-CZ 4.04Å; E448-F508 VanDerWaalsContact O-CZ 3.31Å; E448-F508 WeakPolarHBondContact O-CZ 3.27Å; L450-F508 HydrophobicContact CD1-CE1 3.93Å; L450-F508 HydrophobicContact CD1-CZ 4.13Å; L450-F508 HydrophobicContact CD2-CE1 4.12Å; L450-F508 HydrophobicContact CD2-CE2 4.37Å; L450-F508 HydrophobicContact CD2-CZ 3.65Å; L450-F508 HydrophobicContact CG-CE1 4.19Å; L450-F508 HydrophobicContact CG-CZ 3.86Å; L501-F508 HydrophobicContact CD2-CB 4.46Å; L501-F508 HydrophobicContact CD2-CD2 3.46Å; L501-F508 VanDerWaalsContact CD2-CD2 3.46Å; L501-F508 HydrophobicContact CD2-CE2 3.81Å; L501-F508 HydrophobicContact CD2-CG 4.09Å; G504-F508 PolarHBondContact O-N 2.98Å; G505-F508 WeakPolarHBondContact O-CB 3.33Å; G505-F508 WeakPolarHBondContact O-CD2 3.44Å; G505-F508 PolarHBondContact O-N 2.97Å; D506-F508 VanDerWaalsContact C-N 3.33Å; D506-F508 HydrophobicContact CB-CD2 3.82Å; D506-F508 HydrophobicContact CB-CE2 3.95Å; F508-M510 VanDerWaalsContact C-SD 3.53Å; F508-M510 VanDerWaalsContact CA-SD 3.56Å; F508-M510 HydrophobicContact CB-SD 3.98Å; F508-M510 HydrophobicContact CD1-CE 4.49Å; F508-M510 HydrophobicContact CD1-SD 3.81Å; F508-M510 HydrophobicContact CG-SD 4.32Å; F508-M510 PolarHBondContact O-N 2.92Å; F508-M510 VanDerWaalsContact O-N 3.16Å; F508-I511 HydrophobicContact CB-CB 4.5Å; F508-I511 HydrophobicContact CB-CD1 3.91Å; F508-I511 HydrophobicContact CB-CG1 4.17Å; F508-I511 HydrophobicContact CD1-CD1 3.78Å; F508-I511 HydrophobicContact CD1-CG1 4.35Å; F508-I511 HydrophobicContact CG-CD1 4.14Å; F508-I511 WeakPolarHBondContact O-CB 3.3Å; F508-I511 PolarHBondContact O-N 2.94Å
509Q95.6Very high92.2Very high70 Ų7048.3 Ų48.333%0.32724%0.244SC..Hα-helixtrans-58.7-31.8-177.2-169.463.545.600112.1G507 I511 K512 D513G507-Q509 PolarHBondContact O-N 3.45Å; Q509-I511 PolarHBondContact O-N 3.26Å; Q509-K512 PolarHBondContact O-N 3.32Å; Q509-D513 VanDerWaalsContact CG-OD2 3.32Å; Q509-D513 WeakPolarHBondContact CG-OD2 3.29Å; Q509-D513 VanDerWaalsContact NE2-CG 3.3Å; Q509-D513 PolarHBondContact NE2-OD1 2.94Å; Q509-D513 PolarHBondContact NE2-OD2 3.2Å; Q509-D513 WeakPolarHBondContact O-CB 3.27Å; Q509-D513 PolarHBondContact O-N 3.49Å
510M98.2Very high91.7Very high29 Ų2950.7 Ų50.714%0.14326%0.264CS..Hα-helixtrans-59.9-30.4174.879.2-60.5-64.700112.8T430 K433 A434 H437 F508 E514T430-M510 HydrophobicContact CG2-CG 4.23Å; T430-M510 WeakPolarHBondContact CG2-O 3.4Å; K433-M510 HydrophobicContact CB-CG 4Å; K433-M510 HydrophobicContact CD-CB 4.48Å; A434-M510 HydrophobicContact CB-SD 4.19Å; H437-M510 HydrophobicContact CB-CE 3.8Å; F508-M510 VanDerWaalsContact C-SD 3.53Å; F508-M510 VanDerWaalsContact CA-SD 3.56Å; F508-M510 HydrophobicContact CB-SD 3.98Å; F508-M510 HydrophobicContact CD1-CE 4.49Å; F508-M510 HydrophobicContact CD1-SD 3.81Å; F508-M510 HydrophobicContact CG-SD 4.32Å; F508-M510 PolarHBondContact O-N 2.92Å; F508-M510 VanDerWaalsContact O-N 3.16Å; M510-E514 WeakPolarHBondContact O-CB 3.39Å; M510-E514 WeakPolarHBondContact O-CG 3.47Å; M510-E514 PolarHBondContact O-N 3.14Å; M510-E514 VanDerWaalsContact O-N 3.12Å
511I97.6Very high91.1Very high0 Ų049.1 Ų49.10%027%0.265CS..Hα-helixtrans-68.9-52.9174.9-63.3-177.8000109I388 L426 A434 L497 L501 F508 Q509 D513 L515I388-I511 HydrophobicContact CD1-CD1 4.1Å; L426-I511 HydrophobicContact CD2-CG2 4.27Å; A434-I511 HydrophobicContact CB-CD1 4.33Å; A434-I511 HydrophobicContact CB-CG1 4.37Å; L497-I511 HydrophobicContact CD1-CD1 3.88Å; L497-I511 HydrophobicContact CD1-CG2 3.92Å; L501-I511 HydrophobicContact CB-CD1 4.48Å; F508-I511 HydrophobicContact CB-CB 4.5Å; F508-I511 HydrophobicContact CB-CD1 3.91Å; F508-I511 HydrophobicContact CB-CG1 4.17Å; F508-I511 HydrophobicContact CD1-CD1 3.78Å; F508-I511 HydrophobicContact CD1-CG1 4.35Å; F508-I511 HydrophobicContact CG-CD1 4.14Å; F508-I511 WeakPolarHBondContact O-CB 3.3Å; F508-I511 PolarHBondContact O-N 2.94Å; Q509-I511 PolarHBondContact O-N 3.26Å; I511-D513 VanDerWaalsContact C-N 3.34Å; I511-D513 PolarHBondContact O-N 2.85Å; I511-L515 WeakPolarHBondContact O-CB 3.42Å; I511-L515 WeakPolarHBondContact O-CD2 3.46Å; I511-L515 WeakPolarHBondContact O-CG 3.43Å; I511-L515 PolarHBondContact O-N 3.33Å
512K93.5Very high90.4Very high105 Ų10553.4 Ų53.446%0.45729%0.288SS..Hα-helixtrans-59-43.3-179.2177.8170.5-178.9172.90113N503 Q509N503-K512 WeakPolarHBondContact O-CD 3.44Å; Q509-K512 PolarHBondContact O-N 3.32Å
513D96Very high90Very high111 Ų11157.2 Ų57.259%0.59431%0.305SS*.Hα-helixtrans-80.4-30.5-174.1-69.4-10000113Q509 I511Q509-D513 VanDerWaalsContact CG-OD2 3.32Å; Q509-D513 WeakPolarHBondContact CG-OD2 3.29Å; Q509-D513 VanDerWaalsContact NE2-CG 3.3Å; Q509-D513 PolarHBondContact NE2-OD1 2.94Å; Q509-D513 PolarHBondContact NE2-OD2 3.2Å; Q509-D513 WeakPolarHBondContact O-CB 3.27Å; Q509-D513 PolarHBondContact O-N 3.49Å; I511-D513 VanDerWaalsContact C-N 3.34Å; I511-D513 PolarHBondContact O-N 2.85Å
514E97.7Very high90.1Very high61 Ų6153.5 Ų53.529%0.28529%0.285SS..Hα-helixtrans-110-0.5-172.3-51176.8-16600113.8T430 K433 M510 L516T430-E514 WeakPolarHBondContact CB-OE2 3.36Å; T430-E514 HydrophobicContact CG2-CB 3.76Å; T430-E514 HydrophobicContact CG2-CG 4.44Å; T430-E514 PolarHBondContact OG1-OE2 3.44Å; K433-E514 IonicContact NZ-OE1 2.66Å; K433-E514 PolarHBondContact NZ-OE1 3.02Å; K433-E514 IonicContact NZ-OE2 3.16Å; K433-E514 PolarHBondContact NZ-OE2 3.05Å; M510-E514 WeakPolarHBondContact O-CB 3.39Å; M510-E514 WeakPolarHBondContact O-CG 3.47Å; M510-E514 PolarHBondContact O-N 3.14Å; M510-E514 VanDerWaalsContact O-N 3.12Å; E514-L516 PolarHBondContact O-N 3.3Å
515L92.7Very high90.1Very high46 Ų4653.7 Ų53.724%0.24129%0.286CS..  trans-61.2137.6173.565.184.2000111.3L426 I511 H518L426-L515 HydrophobicContact CD2-CB 3.91Å; I511-L515 WeakPolarHBondContact O-CB 3.42Å; I511-L515 WeakPolarHBondContact O-CD2 3.46Å; I511-L515 WeakPolarHBondContact O-CG 3.43Å; I511-L515 PolarHBondContact O-N 3.33Å; L515-H518 HydrophobicContact CD1-CB 3.88Å; L515-H518 HydrophobicContact CD2-CB 4.21Å
516L93.3Very high90Very high91 Ų9156.6 Ų56.648%0.47630%0.3SS..SBendtrans-92.1-26.5179.8-57.2178.9000111.7Q425 K427 I492 E514Q425-L516 HydrophobicContact CB-CB 4.17Å; Q425-L516 PolarHBondContact O-N 2.91Å; K427-L516 HydrophobicContact CG-CD1 4.35Å; I492-L516 HydrophobicContact CD1-CD1 3.54Å; I492-L516 HydrophobicContact CG1-CD1 3.74Å; I492-L516 HydrophobicContact CG2-CD1 4.08Å; E514-L516 PolarHBondContact O-N 3.3Å
517R83.4Confident89.9Confident127 Ų12756 Ų5648%0.47930%0.296SS..EExtended strand (participates in β ladder)trans-156.6146.1178.5-177.3172.1170.3155.76.3109.1V424 Q425 D519V424-R517 CarbonylContact C-O 3.55Å; V424-R517 WeakPolarHBondContact CA-O 3.38Å; Q425-R517 HydrophobicContact CB-CB 4.03Å; Q425-R517 HydrophobicContact CG-CB 4.05Å; Q425-R517 PolarHBondContact N-O 3.19Å; R517-D519 IonicContact CZ-OD1 3.45Å; R517-D519 IonicContact CZ-OD2 2.87Å; R517-D519 IonicContact NE-OD1 2.62Å; R517-D519 PolarHBondContact NE-OD1 3.45Å; R517-D519 IonicContact NE-OD2 2.95Å; R517-D519 PolarHBondContact NE-OD2 3.43Å; R517-D519 IonicContact NH2-OD1 3.5Å; R517-D519 PolarHBondContact NH2-OD1 2.89Å; R517-D519 IonicContact NH2-OD2 3.43Å; R517-D519 PolarHBondContact NH2-OD2 3.24Å
518H91.1Very high90.1Very high63 Ų6354.5 Ų54.529%0.29228%0.281SS..EExtended strand (participates in β ladder)trans-140.5120176.4172.5-155.8000108.4D422 L423 V424 L515D422-H518 IonicContact OD2-CD2 3.82Å; D422-H518 IonicContact OD2-CE1 3.77Å; D422-H518 IonicContact OD2-NE2 2.9Å; D422-H518 PolarHBondContact OD2-NE2 2.96Å; L423-H518 WeakPolarHBondContact O-CA 3.25Å; V424-H518 HydrophobicContact CG1-CB 4.21Å; L515-H518 HydrophobicContact CD1-CB 3.88Å; L515-H518 HydrophobicContact CD2-CB 4.21Å
519D75.6Confident90Very high58 Ų5854.9 Ų54.931%0.3128%0.284SS..EExtended strand (participates in β ladder)trans-117.2122.8173-56.5-77.1000107.9L423 R517 G521L423-D519 PolarHBondContact N-O 2.75Å; L423-D519 PolarHBondContact O-N 3.42Å; R517-D519 IonicContact CZ-OD1 3.45Å; R517-D519 IonicContact CZ-OD2 2.87Å; R517-D519 IonicContact NE-OD1 2.62Å; R517-D519 PolarHBondContact NE-OD1 3.45Å; R517-D519 IonicContact NE-OD2 2.95Å; R517-D519 PolarHBondContact NE-OD2 3.43Å; R517-D519 IonicContact NH2-OD1 3.5Å; R517-D519 PolarHBondContact NH2-OD1 2.89Å; R517-D519 IonicContact NH2-OD2 3.43Å; R517-D519 PolarHBondContact NH2-OD2 3.24Å; D519-G521 PolarHBondContact O-N 2.88Å
520S78.8Confident89.8Confident97 Ų9755.3 Ų55.368%0.67829%0.291SS*.EExtended strand (participates in β ladder)trans-63.7134.5174.3-61.20000110.6D422D422-S520 WeakPolarHBondContact OD1-CA 3.43Å
521G79.9Confident89.7Confident28 Ų2855.6 Ų55.629%0.28929%0.291SS..EExtended strand (participates in β ladder)trans-105.5-159.4-179.100000113.5F421 D422 D519F421-G521 VanDerWaalsContact O-CA 3.31Å; F421-G521 WeakPolarHBondContact O-CA 3.32Å; D422-G521 PolarHBondContact OD1-N 3.42Å; D519-G521 PolarHBondContact O-N 2.88Å
522D81.2Confident89.7Confident89 Ų8955.6 Ų55.648%0.47629%0.291SS..EExtended strand (participates in β ladder)trans-79.5159.4-178.4-62.6-45.2000111.7N371 T420 F421 D524 V527N371-D522 PolarHBondContact ND2-OD2 2.73Å; T420-D522 CarbonylContact C-O 3.49Å; T420-D522 VanDerWaalsContact CA-O 3.27Å; T420-D522 WeakPolarHBondContact CA-O 3.3Å; T420-D522 WeakPolarHBondContact CB-O 3.33Å; F421-D522 PolarHBondContact N-O 3.48Å; D522-D524 PolarHBondContact O-N 2.89Å; D522-V527 HydrophobicContact CB-CG2 3.65Å
523Q83.8Confident89.8Confident81 Ų8152.5 Ų52.538%0.37928%0.282SS..EExtended strand (participates in β ladder)trans-60.7134.8178.3-166.2176.67.600111.7G419 I525 N526 V527G419-Q523 WeakPolarHBondContact O-CA 3.16Å; Q523-I525 HydrophobicContact CG-CG2 4.21Å; Q523-I525 PolarHBondContact O-N 3.29Å; Q523-N526 HydrophobicContact CB-CB 4.18Å; Q523-N526 WeakPolarHBondContact O-CB 3.28Å; Q523-N526 PolarHBondContact O-N 3.33Å; Q523-N526 PolarHBondContact OE1-ND2 3.04Å; Q523-V527 WeakPolarHBondContact O-CG2 3.47Å; Q523-V527 PolarHBondContact O-N 3.25Å
524D91.1Very high89.8Confident9 Ų953.1 Ų53.15%0.04828%0.28CS..Hα-helixtrans-49.6-54.2-173.254.95.3000113.8L415 G419 F421 D522 N526 V527 V528L415-D524 HydrophobicContact CD1-CB 4.24Å; G419-D524 PolarHBondContact N-OD2 2.76Å; G419-D524 VanDerWaalsContact O-CG 3.3Å; G419-D524 PolarHBondContact O-N 3.01Å; F421-D524 HydrophobicContact CD1-CB 4.41Å; F421-D524 HydrophobicContact CD2-CB 4.27Å; F421-D524 HydrophobicContact CE1-CB 3.94Å; F421-D524 VanDerWaalsContact CE2-CA 3.48Å; F421-D524 HydrophobicContact CE2-CB 3.82Å; F421-D524 WeakPolarHBondContact CE2-O 3.18Å; F421-D524 HydrophobicContact CZ-CB 3.63Å; D522-D524 PolarHBondContact O-N 2.89Å; D524-N526 PolarHBondContact O-N 3.42Å; D524-V527 PolarHBondContact O-N 3.23Å; D524-V528 PolarHBondContact O-N 3.44Å
525I91.3Very high89.8Confident8 Ų853.7 Ų53.74%0.04128%0.283CS..Hα-helixtrans-68.5-31.6-179.5-168.4163.5000112.6W408 L411 A412 Q523 S529W408-I525 HydrophobicContact CD2-CD1 3.91Å; W408-I525 HydrophobicContact CD2-CG1 4.24Å; W408-I525 VanDerWaalsContact CE2-CD1 3.42Å; W408-I525 HydrophobicContact CE3-CG1 4.37Å; W408-I525 HydrophobicContact CG-CD1 4.34Å; W408-I525 HydrophobicContact CH2-CB 4.15Å; W408-I525 HydrophobicContact CH2-CD1 4.22Å; W408-I525 HydrophobicContact CH2-CG1 3.68Å; W408-I525 HydrophobicContact CH2-CG2 3.66Å; W408-I525 HydrophobicContact CZ2-CB 4.02Å; W408-I525 HydrophobicContact CZ2-CD1 3.62Å; W408-I525 HydrophobicContact CZ2-CG1 3.56Å; W408-I525 HydrophobicContact CZ2-CG2 3.32Å; W408-I525 HydrophobicContact CZ3-CG1 4.12Å; L411-I525 HydrophobicContact CB-CD1 3.79Å; L411-I525 HydrophobicContact CB-CG1 3.8Å; L411-I525 HydrophobicContact CD1-CG1 4.37Å; A412-I525 HydrophobicContact CB-CD1 3.89Å; Q523-I525 HydrophobicContact CG-CG2 4.21Å; Q523-I525 PolarHBondContact O-N 3.29Å; I525-S529 WeakPolarHBondContact O-CB 3.07Å; I525-S529 PolarHBondContact O-N 2.83Å; I525-S529 PolarHBondContact O-OG 3.31Å
526N84.8Confident90Very high67 Ų6758.1 Ų58.136%0.35830%0.3SS..Hα-helixtrans-67.3-40.5175.5-69.8-7.9000110.8W408 Q523 D524 S529 T530W408-N526 WeakPolarHBondContact CH2-OD1 3.5Å; Q523-N526 HydrophobicContact CB-CB 4.18Å; Q523-N526 WeakPolarHBondContact O-CB 3.28Å; Q523-N526 PolarHBondContact O-N 3.33Å; Q523-N526 PolarHBondContact OE1-ND2 3.04Å; D524-N526 PolarHBondContact O-N 3.42Å; N526-S529 VanDerWaalsContact CA-OG 3.31Å; N526-S529 WeakPolarHBondContact CA-OG 3.33Å; N526-S529 PolarHBondContact O-OG 3.31Å; N526-T530 VanDerWaalsContact O-CB 3.26Å; N526-T530 WeakPolarHBondContact O-CB 3.37Å; N526-T530 PolarHBondContact O-N 3.5Å; N526-T530 PolarHBondContact O-OG1 3.47Å
527V91.8Very high90.2Very high2 Ų256.7 Ų56.71%0.01230%0.296CS..Hα-helixtrans-61.9-50.3177.41690000110.6A367 M368 N371 F421 D522 Q523 D524 Y531A367-V527 HydrophobicContact CB-CG1 4.31Å; M368-V527 HydrophobicContact CG-CG1 4.36Å; N371-V527 HydrophobicContact CB-CG1 3.8Å; N371-V527 HydrophobicContact CB-CG2 4.33Å; F421-V527 HydrophobicContact CD2-CB 3.75Å; F421-V527 HydrophobicContact CD2-CG1 3.78Å; F421-V527 HydrophobicContact CD2-CG2 3.98Å; F421-V527 HydrophobicContact CE2-CB 4.07Å; F421-V527 HydrophobicContact CE2-CG1 4.11Å; D522-V527 HydrophobicContact CB-CG2 3.65Å; Q523-V527 WeakPolarHBondContact O-CG2 3.47Å; Q523-V527 PolarHBondContact O-N 3.25Å; D524-V527 PolarHBondContact O-N 3.23Å; V527-Y531 PolarHBondContact O-N 3.06Å; V527-Y531 VanDerWaalsContact O-N 3.14Å
528V97.4Very high91Very high2 Ų251 Ų511%0.01228%0.275CS..Hα-helixtrans-68.5-43.1-178.7-178.70000111.4I364 A367 L411 L415 F421 D524 T530 Y531 I532I364-V528 HydrophobicContact CB-CG2 4.45Å; I364-V528 HydrophobicContact CG1-CG2 4.19Å; I364-V528 HydrophobicContact CG2-CG2 4.01Å; A367-V528 HydrophobicContact CB-CG2 4.34Å; L411-V528 HydrophobicContact CD1-CG1 4.28Å; L411-V528 HydrophobicContact CD2-CG1 3.85Å; L415-V528 HydrophobicContact CD1-CB 4.42Å; L415-V528 HydrophobicContact CD1-CG2 3.7Å; F421-V528 HydrophobicContact CE2-CG2 4.1Å; D524-V528 PolarHBondContact O-N 3.44Å; V528-T530 PolarHBondContact O-N 3.29Å; V528-Y531 PolarHBondContact O-N 2.84Å; V528-I532 HydrophobicContact CG1-CD1 3.81Å; V528-I532 HydrophobicContact CG1-CG1 4.34Å; V528-I532 VanDerWaalsContact O-CG1 3.3Å; V528-I532 WeakPolarHBondContact O-CG1 3.39Å; V528-I532 PolarHBondContact O-N 2.87Å
529S94.6Very high91.3Very high9 Ų955.7 Ų55.76%0.06329%0.291CS..Hα-helixtrans-63.8-40.6178.859.30000113.1W408 I525 N526 I532 S533W408-S529 WeakPolarHBondContact CZ3-OG 3.01Å; I525-S529 WeakPolarHBondContact O-CB 3.07Å; I525-S529 PolarHBondContact O-N 2.83Å; I525-S529 PolarHBondContact O-OG 3.31Å; N526-S529 VanDerWaalsContact CA-OG 3.31Å; N526-S529 WeakPolarHBondContact CA-OG 3.33Å; N526-S529 PolarHBondContact O-OG 3.31Å; S529-I532 PolarHBondContact O-N 2.92Å; S529-S533 VanDerWaalsContact O-CB 3.25Å; S529-S533 WeakPolarHBondContact O-CB 3.46Å; S529-S533 PolarHBondContact O-N 2.86Å; S529-S533 PolarHBondContact O-OG 3.45Å
530T91.7Very high92.4Very high78 Ų7853.9 Ų53.948%0.47928%0.282SS..Hα-helixtrans-60.5-44.9173.3-67.70000111.1N526 V528 S533 K534N526-T530 VanDerWaalsContact O-CB 3.26Å; N526-T530 WeakPolarHBondContact O-CB 3.37Å; N526-T530 PolarHBondContact O-N 3.5Å; N526-T530 PolarHBondContact O-OG1 3.47Å; V528-T530 PolarHBondContact O-N 3.29Å; T530-S533 PolarHBondContact O-N 3.03Å; T530-K534 VanDerWaalsContact O-CB 3.31Å; T530-K534 WeakPolarHBondContact O-CB 3.44Å; T530-K534 PolarHBondContact O-N 2.97Å
531Y97.1Very high93.3Very high36 Ų3651.5 Ų51.514%0.14127%0.269CS..Hα-helixtrans-61.2-48177.9-178-99.4000112.1L363 A367 N370 V527 V528 S533 K534 M535L363-Y531 HydrophobicContact CD1-CD1 3.86Å; L363-Y531 HydrophobicContact CD1-CE1 3.6Å; A367-Y531 VanDerWaalsContact CB-CB 3.45Å; A367-Y531 HydrophobicContact CB-CD1 3.91Å; A367-Y531 HydrophobicContact CB-CD2 4.15Å; A367-Y531 HydrophobicContact CB-CG 3.57Å; N370-Y531 HydrophobicContact CB-CD2 3.57Å; N370-Y531 HydrophobicContact CB-CE2 3.75Å; V527-Y531 PolarHBondContact O-N 3.06Å; V527-Y531 VanDerWaalsContact O-N 3.14Å; V528-Y531 PolarHBondContact O-N 2.84Å; Y531-S533 VanDerWaalsContact C-N 3.33Å; Y531-S533 PolarHBondContact O-N 2.76Å; Y531-K534 WeakPolarHBondContact O-CB 3.37Å; Y531-K534 PolarHBondContact O-N 3.23Å; Y531-M535 HydrophobicContact CD1-CG 4.21Å; Y531-M535 HydrophobicContact CD2-CE 4.01Å; Y531-M535 HydrophobicContact CD2-CG 4.39Å; Y531-M535 HydrophobicContact CE1-CG 3.82Å; Y531-M535 HydrophobicContact CE2-CE 3.29Å; Y531-M535 HydrophobicContact CE2-CG 4.05Å; Y531-M535 HydrophobicContact CG-CG 4.49Å; Y531-M535 WeakPolarHBondContact O-CG 3.36Å; Y531-M535 PolarHBondContact O-N 3.34Å
532I97.7Very high94.2Very high0 Ų054.5 Ų54.50%028%0.281CS..Hα-helixtrans-61.4-44.7177.9-66.9176.3000110.5L339 I406 L411 V528 S529 K534 M535 K536 I538L339-I532 HydrophobicContact CB-CG2 4.21Å; I406-I532 HydrophobicContact CD1-CD1 4.02Å; I406-I532 HydrophobicContact CD1-CG2 4.05Å; I406-I532 HydrophobicContact CG2-CD1 4.11Å; L411-I532 HydrophobicContact CD1-CD1 4.21Å; L411-I532 HydrophobicContact CD2-CD1 3.8Å; V528-I532 HydrophobicContact CG1-CD1 3.81Å; V528-I532 HydrophobicContact CG1-CG1 4.34Å; V528-I532 VanDerWaalsContact O-CG1 3.3Å; V528-I532 WeakPolarHBondContact O-CG1 3.39Å; V528-I532 PolarHBondContact O-N 2.87Å; S529-I532 PolarHBondContact O-N 2.92Å; I532-K534 VanDerWaalsContact C-N 3.26Å; I532-K534 PolarHBondContact O-N 3.48Å; I532-M535 PolarHBondContact O-N 2.99Å; I532-K536 PolarHBondContact O-N 3.14Å; I532-I538 HydrophobicContact CD1-CD1 4.21Å; I532-I538 HydrophobicContact CG1-CD1 4.06Å
533S95.6Very high95Very high39 Ų3956.1 Ų56.127%0.27329%0.286SS..Hα-helixtrans-62.5-33.1177.7-59.90000112.9L339 S529 T530 Y531 K536L339-S533 VanDerWaalsContact O-CA 3.28Å; L339-S533 WeakPolarHBondContact O-CA 3.34Å; L339-S533 PolarHBondContact O-OG 3.33Å; S529-S533 VanDerWaalsContact O-CB 3.25Å; S529-S533 WeakPolarHBondContact O-CB 3.46Å; S529-S533 PolarHBondContact O-N 2.86Å; S529-S533 PolarHBondContact O-OG 3.45Å; T530-S533 PolarHBondContact O-N 3.03Å; Y531-S533 VanDerWaalsContact C-N 3.33Å; Y531-S533 PolarHBondContact O-N 2.76Å; S533-K536 VanDerWaalsContact O-CD 3.26Å; S533-K536 WeakPolarHBondContact O-CD 3.49Å; S533-K536 WeakPolarHBondContact O-CE 3.31Å; S533-K536 PolarHBondContact O-NZ 3.41Å
534K96.1Very high95.7Very high124 Ų12453.1 Ų53.154%0.53928%0.277SS..Hα-helixtrans-73.4-46.2175.6178.4178.1176.8178.40111.7N370 T530 Y531 I532 K536N370-K534 PolarHBondContact OD1-NZ 3.42Å; T530-K534 VanDerWaalsContact O-CB 3.31Å; T530-K534 WeakPolarHBondContact O-CB 3.44Å; T530-K534 PolarHBondContact O-N 2.97Å; Y531-K534 WeakPolarHBondContact O-CB 3.37Å; Y531-K534 PolarHBondContact O-N 3.23Å; I532-K534 VanDerWaalsContact C-N 3.26Å; I532-K534 PolarHBondContact O-N 3.48Å; K534-K536 VanDerWaalsContact C-N 3.33Å
535M97.8Very high96Very high74 Ų7453.4 Ų53.437%0.36528%0.277SS..Hα-helixtrans-74-24.3-177.6-65.4-54168.600113.2Y531 I532 V537 I538Y531-M535 HydrophobicContact CD1-CG 4.21Å; Y531-M535 HydrophobicContact CD2-CE 4.01Å; Y531-M535 HydrophobicContact CD2-CG 4.39Å; Y531-M535 HydrophobicContact CE1-CG 3.82Å; Y531-M535 HydrophobicContact CE2-CE 3.29Å; Y531-M535 HydrophobicContact CE2-CG 4.05Å; Y531-M535 HydrophobicContact CG-CG 4.49Å; Y531-M535 WeakPolarHBondContact O-CG 3.36Å; Y531-M535 PolarHBondContact O-N 3.34Å; I532-M535 PolarHBondContact O-N 2.99Å; M535-V537 PolarHBondContact O-N 3.45Å; M535-I538 HydrophobicContact CB-CG2 3.75Å; M535-I538 HydrophobicContact CG-CG2 4.41Å
536K96.4Very high96.4Very high138 Ų13853.6 Ų53.660%0.628%0.278SS*.SBendtrans64.6-53.9-174.8-53.3-62.4179.2-162.70113.6G340 K341 I532 S533 K534G340-K536 WeakPolarHBondContact CA-O 3.19Å; K341-K536 PolarHBondContact N-O 3.47Å; I532-K536 PolarHBondContact O-N 3.14Å; S533-K536 VanDerWaalsContact O-CD 3.26Å; S533-K536 WeakPolarHBondContact O-CD 3.49Å; S533-K536 WeakPolarHBondContact O-CE 3.31Å; S533-K536 PolarHBondContact O-NZ 3.41Å; K534-K536 VanDerWaalsContact C-N 3.33Å
537V98.1Very high97Very high62 Ų6256 Ų5638%0.37629%0.285SS..EExtended strand (participates in β ladder)trans-125122177.2-175.70000109.1K341 I343 M535K341-V537 CarbonylContact O-C 3.46Å; K341-V537 VanDerWaalsContact O-CA 3.26Å; K341-V537 WeakPolarHBondContact O-CA 3.48Å; I343-V537 HydrophobicContact CB-CG1 4.47Å; I343-V537 HydrophobicContact CD1-CG1 4.29Å; I343-V537 HydrophobicContact CG1-CG1 4.12Å; I343-V537 HydrophobicContact CG2-CG1 3.66Å; M535-V537 PolarHBondContact O-N 3.45Å
538I98.4Very high97.3Very high7 Ų759.2 Ų59.24%0.03630%0.299CS..EExtended strand (participates in β ladder)trans-111151.2-179.965.9179.9000111.8K341 T342 I343 L346 L363 I406 I532 M535K341-I538 PolarHBondContact O-N 3.22Å; T342-I538 WeakPolarHBondContact CA-O 3.31Å; I343-I538 PolarHBondContact N-O 3.36Å; I343-I538 VanDerWaalsContact N-O 3.13Å; L346-I538 HydrophobicContact CD1-CD1 3.95Å; L346-I538 HydrophobicContact CD2-CD1 4.33Å; L363-I538 HydrophobicContact CD1-CB 4.48Å; L363-I538 HydrophobicContact CD1-CD1 3.89Å; L363-I538 HydrophobicContact CD1-CG2 4.43Å; L363-I538 HydrophobicContact CD2-CD1 3.59Å; L363-I538 HydrophobicContact CG-CD1 4.4Å; I406-I538 HydrophobicContact CD1-CD1 3.58Å; I406-I538 HydrophobicContact CD1-CG1 4.2Å; I532-I538 HydrophobicContact CD1-CD1 4.21Å; I532-I538 HydrophobicContact CG1-CD1 4.06Å; M535-I538 HydrophobicContact CB-CG2 3.75Å; M535-I538 HydrophobicContact CG-CG2 4.41Å
539Y98.3Very high97Very high161 Ų16161.5 Ų61.563%0.63132%0.315SS*.  trans-15149.4-177.947.7-88.9000111.9I343 A541I343-Y539 HydrophobicContact CD1-CD1 4.29Å; I343-Y539 HydrophobicContact CD1-CG 4.46Å; Y539-A541 PolarHBondContact O-N 3.2Å
540P98.4Very high96.1Very high20 Ų2068.1 Ų68.113%0.1336%0.355CS..  trans-59.5137.5-178.230.5-38000110.7V344 L346 N359 L363V344-P540 HydrophobicContact CG2-CG 4.34Å; L346-P540 HydrophobicContact CD2-CG 3.42Å; L346-P540 VanDerWaalsContact CD2-CG 3.42Å; N359-P540 HydrophobicContact CB-CB 4.19Å; N359-P540 HydrophobicContact CB-CG 4.29Å; N359-P540 WeakPolarHBondContact CB-O 3.43Å; N359-P540 PolarHBondContact ND2-O 2.01Å; N359-P540 WeakPolarHBondContact O-CB 3.26Å; L363-P540 HydrophobicContact CB-CB 4.06Å; L363-P540 HydrophobicContact CB-CG 4Å
541A98.4Very high94.4Very high48 Ų4865 Ų6540%0.39734%0.339SS..  trans-108.9168.1178.900000111.4N362 Y539 E543N362-A541 PolarHBondContact ND2-O 2.71Å; Y539-A541 PolarHBondContact O-N 3.2Å; A541-E543 HydrophobicContact CB-CG 3.96Å
542V98.6Very high91.8Very high91 Ų9169.1 Ų69.155%0.55237%0.373SS*.  trans-89.8115.5161.11740000106.9E357 N359E357-V542 HydrophobicContact CB-CG1 4.03Å; E357-V542 HydrophobicContact CG-CG1 4Å; N359-V542 HydrophobicContact CB-CG2 4.35Å
543E98Very high89Confident122 Ų12277.2 Ų77.257%0.5741%0.41SS*.  trans-113.8-1.7-163.9-59.9176.3129.300112.5E357 A541 R545E357-E543 PolarHBondContact OE1-N 2.87Å; A541-E543 HydrophobicContact CB-CG 3.96Å; E543-R545 HydrophobicContact CB-CG 4.5Å; E543-R545 IonicContact OE2-CZ 3.77Å; E543-R545 IonicContact OE2-NE 2.86Å; E543-R545 PolarHBondContact OE2-NE 3.14Å; E543-R545 VanDerWaalsContact OE2-NE 3.14Å; E543-R545 IonicContact OE2-NH2 2.89Å; E543-R545 PolarHBondContact OE2-NH2 3.42Å
544G97.9Very high86.2Confident18 Ų1880.5 Ų80.519%0.18643%0.432CS..SBendtrans80.731.3-175.800000112.5E357 I546 K547E357-G544 PolarHBondContact OE1-N 3.39Å; E357-G544 VanDerWaalsContact OE2-C 3.29Å; E357-G544 WeakPolarHBondContact OE2-CA 3.13Å; E357-G544 PolarHBondContact OE2-N 2.76Å; G544-I546 PolarHBondContact O-N 3.33Å; G544-K547 VanDerWaalsContact O-CE 3.29Å; G544-K547 WeakPolarHBondContact O-CE 3.26Å
545R98.6Very high83.3Confident16 Ų1684.3 Ų84.36%0.0645%0.452CS..SBendtrans-62-32167-56.3-176.5-171.2-167.8-1.5111E357 N362 D366 V452 H456 V457 E543E357-R545 PolarHBondContact OE1-N 2.84Å; E357-R545 PolarHBondContact OE2-N 2.93Å; N362-R545 WeakPolarHBondContact OD1-CD 3.38Å; D366-R545 IonicContact OD1-CZ 3.61Å; D366-R545 IonicContact OD1-NH1 3.84Å; D366-R545 PolarHBondContact OD1-NH1 3.36Å; D366-R545 IonicContact OD1-NH2 3.91Å; D366-R545 PolarHBondContact OD1-NH2 2.9Å; D366-R545 VanDerWaalsContact OD1-NH2 3.16Å; D366-R545 IonicContact OD2-CZ 3.24Å; D366-R545 IonicContact OD2-NH1 3.28Å; D366-R545 IonicContact OD2-NH2 2.62Å; D366-R545 PolarHBondContact OD2-NH2 2.97Å; V452-R545 HydrophobicContact CG2-CB 3.72Å; V452-R545 WeakPolarHBondContact O-CD 3.39Å; V452-R545 PolarHBondContact O-NH1 2.93Å; H456-R545 CarbonylContact C-O 3.57Å; H456-R545 WeakPolarHBondContact CA-O 3.48Å; V457-R545 PolarHBondContact N-O 3.44Å; E543-R545 HydrophobicContact CB-CG 4.5Å; E543-R545 IonicContact OE2-CZ 3.77Å; E543-R545 IonicContact OE2-NE 2.86Å; E543-R545 PolarHBondContact OE2-NE 3.14Å; E543-R545 VanDerWaalsContact OE2-NE 3.14Å; E543-R545 IonicContact OE2-NH2 2.89Å; E543-R545 PolarHBondContact OE2-NH2 3.42Å
546I98.8Very high80.4Confident11 Ų1184 Ų846%0.05647%0.467CS..EExtended strand (participates in β ladder)trans-124.2123.7176-53165.2000109.3E357 F449 L450 V452 V457 Y459 G544E357-I546 HydrophobicContact CB-CB 4.14Å; E357-I546 HydrophobicContact CB-CD1 4.3Å; E357-I546 HydrophobicContact CB-CG1 4.48Å; E357-I546 PolarHBondContact OE2-N 2.79Å; F449-I546 HydrophobicContact CE1-CD1 3.85Å; F449-I546 HydrophobicContact CZ-CD1 4.12Å; F449-I546 HydrophobicContact CZ-CG2 3.82Å; L450-I546 WeakPolarHBondContact O-CD1 3.41Å; V452-I546 HydrophobicContact CG2-CD1 4.32Å; V452-I546 HydrophobicContact CG2-CG1 3.95Å; V457-I546 HydrophobicContact CG1-CB 4.11Å; V457-I546 HydrophobicContact CG1-CG1 3.81Å; V457-I546 HydrophobicContact CG1-CG2 3.92Å; Y459-I546 HydrophobicContact CD2-CG2 3.95Å; Y459-I546 HydrophobicContact CE2-CG2 3.59Å; G544-I546 PolarHBondContact O-N 3.33Å
547K98.3Very high77.5Confident119 Ų11981.5 Ų81.552%0.51747%0.467SS..EExtended strand (participates in β ladder)trans-126.2151.7178.7-64.7-180-179.9174.20111.8V457 V458 Y459 G544V457-K547 PolarHBondContact O-N 3.48Å; V458-K547 CarbonylContact C-O 3.55Å; V458-K547 WeakPolarHBondContact CA-O 3.28Å; V458-K547 HydrophobicContact CG1-CB 4.32Å; V458-K547 HydrophobicContact CG2-CB 4.27Å; Y459-K547 PolarHBondContact N-O 2.94Å; G544-K547 VanDerWaalsContact O-CE 3.29Å; G544-K547 WeakPolarHBondContact O-CE 3.26Å
548F96.9Very high74.5Confident68 Ų6887.2 Ų87.230%0.29849%0.487SS..EExtended strand (participates in β ladder)trans-111.8127.1169.9-61.4-84.9000108.9F355 R356 Y442 F449 Y459 L461F355-F548 WeakPolarHBondContact O-CE2 3.3Å; F355-F548 VanDerWaalsContact O-CZ 3.29Å; F355-F548 WeakPolarHBondContact O-CZ 3.42Å; R356-F548 HydrophobicContact CB-CE2 4.3Å; Y442-F548 HydrophobicContact CD2-CE1 4.48Å; Y442-F548 AromaticContact CE2-CE1 3.96Å; Y442-F548 HydrophobicContact CE2-CE1 3.96Å; Y442-F548 AromaticContact CE2-CZ 3.71Å; Y442-F548 HydrophobicContact CE2-CZ 3.71Å; Y442-F548 AromaticContact CZ-CZ 3.98Å; F449-F548 HydrophobicContact CE2-CE1 4.44Å; F449-F548 AromaticContact CE2-CZ 3.76Å; F449-F548 HydrophobicContact CE2-CZ 3.76Å; F449-F548 HydrophobicContact CZ-CE2 4.5Å; F449-F548 AromaticContact CZ-CZ 3.94Å; F449-F548 HydrophobicContact CZ-CZ 3.94Å; Y459-F548 HydrophobicContact CD2-CD1 4.26Å; Y459-F548 AromaticContact CD2-CE1 3.88Å; Y459-F548 HydrophobicContact CD2-CE1 3.88Å; Y459-F548 HydrophobicContact CD2-CZ 4.36Å; Y459-F548 HydrophobicContact CG-CE1 4.36Å; Y459-F548 CarbonylContact O-C 3.57Å; Y459-F548 WeakPolarHBondContact O-CA 3.35Å; L461-F548 HydrophobicContact CD1-CD1 3.75Å; L461-F548 HydrophobicContact CD1-CE1 3.87Å; L461-F548 HydrophobicContact CD2-CD1 4.3Å; L461-F548 HydrophobicContact CD2-CE1 4.13Å; L461-F548 HydrophobicContact CG-CD1 3.85Å; L461-F548 HydrophobicContact CG-CE1 4.12Å
549S92.3Very high71.7Confident51 Ų5191.7 Ų91.736%0.35752%0.519SS..  trans-69.3140.8170.3-178.50000109.3Y459 G551Y459-S549 WeakPolarHBondContact O-CB 3.36Å; Y459-S549 PolarHBondContact O-N 3.37Å; S549-G551 PolarHBondContact O-N 2.82Å; S549-G551 PolarHBondContact OG-N 3.12Å
550T74.6Confident68.8Low147 Ų14790.2 Ų90.290%0.90252%0.522SS*.  trans-75.44.417545.90000113.5
551G55.4Low66.1Low12 Ų1294.7 Ų94.712%0.12454%0.543CS..  trans72145.8-17400000111.7S549 H553S549-G551 PolarHBondContact O-N 2.82Å; S549-G551 PolarHBondContact OG-N 3.12Å; G551-H553 PolarHBondContact O-N 2.82Å
552S43.3Very low63.2Low124 Ų124100.6 Ų100.687%0.86756%0.56SS**SBendtrans-79.565173.8-62.50000110.6
553H39.4Very low60.5Low169 Ų169102.6 Ų102.678%0.78257%0.567SS**  trans-109.34.8171.9-81.5-50000114.1G551G551-H553 PolarHBondContact O-N 2.82Å
554C35.6Very low57.7Low109 Ų109100.1 Ų100.174%0.73656%0.563SS**  trans-105.138.8-179.8-103.10000114.3
555H35.2Very low55Low204 Ų204107 Ų10794%0.94459%0.588SS**SBendtrans-13169.4164.9-89.522.6000109.9
556G37.7Very low52.3Low67 Ų67110.5 Ų110.569%0.69161%0.614SS**SBendtrans17741.6177.400000114.6
557S34.7Very low49.7Very low85 Ų85113.1 Ų113.159%0.59464%0.637SS**SBendtrans-162.42.9167.4-81.50000115.2S559S557-S559 VanDerWaalsContact C-N 3.33Å; S557-S559 PolarHBondContact O-N 3.23Å
558F35.3Very low47.2Very low183 Ų183112.2 Ų112.280%0.80364%0.642SS**THydrogen-bonded Turntrans-79.3-11.3177.7-97.5-83.6000114.5
559S39.1Very low44.8Very low100 Ų100115.1 Ų115.170%0.69966%0.659SS**THydrogen-bonded Turntrans-91.3-10.7179.8-52.70000114.7S557S557-S559 VanDerWaalsContact C-N 3.33Å; S557-S559 PolarHBondContact O-N 3.23Å
560L38.8Very low42.4Very low131 Ų131121.5 Ų121.569%0.68668%0.681SS**THydrogen-bonded Turntrans-98.7-16.4-176.9-87.1154000114.2S564L560-S564 PolarHBondContact O-OG 3.33Å
561I40.4Very low41.2Very low114 Ų114120.4 Ų120.459%0.58567%0.673SS**Hα-helixtrans-85.4-20177.8-60.9176000111.6S564I561-S564 PolarHBondContact O-OG 3.14Å
562F38Very low40.6Very low171 Ų171126.8 Ų126.875%0.7570%0.704SS**Hα-helixtrans-79.8-23176.5-125.1-92.9000113.7
563L41.4Very low40.8Very low134 Ų134131.1 Ų131.170%0.70270%0.703SS**Hα-helixtrans-83.5-21.6179-89.2153.4000113.4
564S40.4Very low40.9Very low70 Ų70135.9 Ų135.949%0.4973%0.725SS.*Hα-helixtrans-85.6-18.217826.80000113.2L560 I561L560-S564 PolarHBondContact O-OG 3.33Å; I561-S564 PolarHBondContact O-OG 3.14Å
565F40.3Very low41.2Very low162 Ų162137.2 Ų137.271%0.71173%0.725SS**Hα-helixtrans-83.2-21.9176.7-117.4-94000114.2
566C43.3Very low41.5Very low90 Ų90133.7 Ų133.761%0.60871%0.713SS**SBendtrans-83-18.2176.6-70.70000113.9
567A43.6Very low41.7Very low65 Ų65137.4 Ų137.454%0.53771%0.714SS.*SBendtrans-83-18.7-178.300000114
568V45.7Very low42.1Very low101 Ų101140.5 Ų140.561%0.61272%0.721SS**SBendtrans-86.6-16-176.7-178.50000112.7
569I46.3Very low42.5Very low128 Ų128137.8 Ų137.866%0.65672%0.716SS**THydrogen-bonded Turntrans-81.8-18.2178.7-65.9176.9000112.4
570F42Very low42.8Very low186 Ų186140.3 Ų140.382%0.81672%0.717SS**THydrogen-bonded Turntrans-88.9-4.1-178.6-109-84.5000115.5
571V49.9Very low43Very low123 Ų123141 Ų14175%0.74572%0.72SS**SBendtrans-104.5-3.1-178.6-176.60000112.8
572L43.4Very low43.3Very low146 Ų146143.1 Ų143.176%0.76473%0.73SS**SBendtrans-103.311.9176.8-77.5166.2000114.2
573Y46.1Very low43.7Very low215 Ų215140.8 Ų140.884%0.84373%0.728SS**  trans-133.468.9169.6-94.4-87.2000110.5
574Q41.9Very low43.9Very low269 Ų269141.4 Ų141.4100%1.25773%0.731SS**  trans-148.60148.8-81.1-155.6-24.600109.9

Retrieved 574 of 574 residues in 2241.1 ms (Link to these results)