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Homeobox protein MIXL1

Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression.

AlphaFold DB , UniProt , Accession F7I8Q6, Species CALJA (Callithrix jacchus, White-tufted-ear marmoset), Gene MIXL1, Length 236 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	42.3	Very low	48.3	Very low	255 Å²	255	157.5 Å²	157.5	100%	1.256	87%	0.871	S	S	*	*				0	113.4	0	-77.2	173	164.9	0	0	107.2
2	A	36.8	Very low	48.5	Very low	109 Å²	109	152.3 Å²	152.3	90%	0.901	86%	0.864	S	S	*	*			trans	-86.6	140.8	-174.7	0	0	0	0	0	110.9
3	A	46.8	Very low	48.4	Very low	104 Å²	104	154.8 Å²	154.8	86%	0.86	86%	0.864	S	S	*	*			trans	-104.6	124.3	167.5	0	0	0	0	0	108.5
4	A	45.1	Very low	48.1	Very low	98 Å²	98	148.6 Å²	148.6	81%	0.81	85%	0.853	S	S	*	*			trans	-93.3	138.3	175.6	0	0	0	0	0	109.1
5	E	54.1	Low	47.9	Very low	200 Å²	200	145.4 Å²	145.4	94%	0.935	85%	0.851	S	S	*	*			trans	-128	128.3	161.3	-77.7	-170.1	87.6	0	0	110.7
6	S	50	Low	47.9	Very low	123 Å²	123	141.9 Å²	141.9	86%	0.86	85%	0.845	S	S	*	*			trans	-75.3	145.3	-175.4	-66.4	0	0	0	0	112.5
7	R	57.8	Low	47.8	Very low	234 Å²	234	145.4 Å²	145.4	88%	0.883	85%	0.847	S	S	*	*			trans	-144.6	95.3	143.4	-168.5	165.8	170.9	170	-4	110.4
8	A	50.7	Low	48.4	Very low	83 Å²	83	144.6 Å²	144.6	69%	0.686	85%	0.847	S	S	*	*			trans	-76.8	136.6	162.9	0	0	0	0	0	109.5
9	H	51.6	Low	48.5	Very low	156 Å²	156	141.5 Å²	141.5	72%	0.722	84%	0.839	S	S	*	*			trans	176.6	136.6	151.2	-81	-71.7	0	0	0	106
10	Q	55.7	Low	48.4	Very low	166 Å²	166	144.5 Å²	144.5	78%	0.776	84%	0.837	S	S	*	*			cis	-165.2	151.1	-17.3	-134.4	168.6	58	0	0	104.5
11	F	40.2	Very low	48.2	Very low	204 Å²	204	148.4 Å²	148.4	90%	0.895	84%	0.838	S	S	*	*			trans	-58	143.5	171.3	-93.7	-116.3	0	0	0	112
12	A	51	Low	48.5	Very low	95 Å²	95	140.3 Å²	140.3	79%	0.785	81%	0.811	S	S	*	*			trans	-136.7	109.3	143.2	0	0	0	0	0	105.5
13	E	47.5	Very low	49.3	Very low	185 Å²	185	139.9 Å²	139.9	86%	0.864	80%	0.799	S	S	*	*				43.1	118.8	100	-96.3	-149.5	115.2	0	0	112.5
14	G	43.3	Very low	49.5	Very low	69 Å²	69	145.2 Å²	145.2	71%	0.711	80%	0.799	S	S	*	*			cis	109.2	88.4	36.4	0	0	0	0	0	108.4
15	A	46	Very low	49.6	Very low	100 Å²	100	145.2 Å²	145.2	83%	0.826	80%	0.799	S	S	*	*			trans	178.6	101.5	158.5	0	0	0	0	0	108.1
16	A	47.1	Very low	49.4	Very low	90 Å²	90	141.6 Å²	141.6	74%	0.744	80%	0.796	S	S	*	*				93.2	84.6	96	0	0	0	0	0	111.4
17	F	47.4	Very low	49.3	Very low	201 Å²	201	139.5 Å²	139.5	88%	0.882	79%	0.793	S	S	*	*			trans	-56.7	132.4	158.1	-61	-91.8	0	0	0	109.1	A19	F17-A19 VanDerWaalsContact C-N 3.35Å; F17-A19 PolarHBondContact O-N 3.14Å
18	P	57.6	Low	48.7	Very low	130 Å²	130	132.5 Å²	132.5	84%	0.844	79%	0.786	S	S	*	*			trans	-70.7	99.4	165.8	26.3	-28.8	0	0	0	108.5	Y20	P18-Y20 PolarHBondContact O-N 3.1Å
19	A	50.6	Low	48.7	Very low	86 Å²	86	136.4 Å²	136.4	71%	0.711	79%	0.794	S	S	*	*			trans	-58.8	127.3	164.4	0	0	0	0	0	109.6	F17	F17-A19 VanDerWaalsContact C-N 3.35Å; F17-A19 PolarHBondContact O-N 3.14Å
20	Y	45.9	Very low	48.8	Very low	202 Å²	202	136.4 Å²	136.4	79%	0.792	80%	0.798	S	S	*	*			trans	-57.7	128.2	155.4	52.3	-82.9	0	0	0	109.8	P18	P18-Y20 PolarHBondContact O-N 3.1Å
21	R	45.6	Very low	49.3	Very low	227 Å²	227	133.9 Å²	133.9	86%	0.857	80%	0.797	S	S	*	*			trans	173.7	113.5	135.5	-102	-171.3	164.5	169.8	-2.4	109.8
22	A	47	Very low	50.3	Low	84 Å²	84	129.4 Å²	129.4	69%	0.694	79%	0.788	S	S	*	*				93.1	152.3	95.5	0	0	0	0	0	110.4
23	P	54.3	Low	50.7	Low	100 Å²	100	130.6 Å²	130.6	65%	0.649	79%	0.787	S	S	*	*			cis	-137.3	171	28.2	35	-12.6	0	0	0	116.5
24	Y	50.9	Low	51.2	Low	217 Å²	217	127.3 Å²	127.3	85%	0.851	79%	0.785	S	S	*	*			trans	-42.3	130.3	160.7	46.1	-85.9	0	0	0	112.9
25	A	47.7	Very low	51.8	Low	98 Å²	98	129.3 Å²	129.3	81%	0.81	79%	0.786	S	S	*	*			trans	-121.7	127.4	155	0	0	0	0	0	107.5
26	S	48.7	Very low	51.6	Low	124 Å²	124	128.5 Å²	128.5	87%	0.867	78%	0.779	S	S	*	*			trans	-42.4	139.6	-174.6	-63.1	0	0	0	0	116.3
27	G	48.6	Very low	51.8	Low	78 Å²	78	129.1 Å²	129.1	80%	0.804	78%	0.784	S	S	*	*				72.3	101.5	129.5	0	0	0	0	0	117.4
28	A	46.1	Very low	52	Low	88 Å²	88	123.9 Å²	123.9	73%	0.727	78%	0.778	S	S	*	*			trans	-169.7	118.7	137.3	0	0	0	0	0	110.9
29	L	48.8	Very low	51.8	Low	164 Å²	164	125.8 Å²	125.8	86%	0.859	78%	0.78	S	S	*	*			trans	58.6	105.1	137.9	-75.9	142.2	0	0	0	119.4
30	L	55.8	Low	52.2	Low	156 Å²	156	129.7 Å²	129.7	82%	0.817	79%	0.788	S	S	*	*			trans	-31.2	134.4	138.6	-81.5	144.6	0	0	0	111.8
31	P	64.2	Low	52.5	Low	114 Å²	114	125.9 Å²	125.9	74%	0.74	79%	0.788	S	S	*	*	P	Polyproline II helix	trans	-65.7	129	166.7	27.5	-31.7	0	0	0	109.2
32	P	62.8	Low	53.1	Low	109 Å²	109	119.4 Å²	119.4	71%	0.708	78%	0.783	S	S	*	*	P	Polyproline II helix	trans	-68.5	149.9	175.1	28	-33.5	0	0	0	110.9	S34	P32-S34 PolarHBondContact O-N 3.31Å
33	P	57.6	Low	53.9	Low	120 Å²	120	121 Å²	121	78%	0.779	79%	0.786	S	S	*	*	P	Polyproline II helix	trans	-66.5	119.8	166.9	28.1	-31.9	0	0	0	108.9	P35	P33-P35 WeakPolarHBondContact O-CD 3.16Å
34	S	58.1	Low	54.2	Low	116 Å²	116	122.3 Å²	122.3	81%	0.811	80%	0.795	S	S	*	*	P	Polyproline II helix	trans	-55.6	117	179.8	-163	0	0	0	0	111.8	P32	P32-S34 PolarHBondContact O-N 3.31Å
35	P	56.4	Low	54.6	Low	112 Å²	112	117 Å²	117	73%	0.727	80%	0.796	S	S	*	*	P	Polyproline II helix	trans	-99.7	133.8	164.9	31.4	-17.3	0	0	0	109.8	P33	P33-P35 WeakPolarHBondContact O-CD 3.16Å
36	A	41.8	Very low	54.9	Low	82 Å²	82	115.2 Å²	115.2	68%	0.678	79%	0.787	S	S	*	*			trans	75.5	124.5	175.9	0	0	0	0	0	114.6
37	A	51.9	Low	55.3	Low	104 Å²	104	115.5 Å²	115.5	86%	0.86	79%	0.786	S	S	*	*			cis	53.7	71.4	40.9	0	0	0	0	0	112.9
38	A	51.4	Low	55.6	Low	91 Å²	91	117.2 Å²	117.2	75%	0.752	79%	0.785	S	S	*	*			trans	-168.4	140.5	147.7	0	0	0	0	0	110.3
39	L	54.1	Low	56	Low	170 Å²	170	119 Å²	119	89%	0.89	79%	0.789	S	S	*	*			trans	85	69	168.1	-55.6	165.6	0	0	0	117
40	L	58.1	Low	56.4	Low	168 Å²	168	114.1 Å²	114.1	88%	0.88	78%	0.779	S	S	*	*	P	Polyproline II helix	trans	-98.1	140.7	138.4	-70.3	178.5	0	0	0	108.9
41	P	52.5	Low	56.4	Low	121 Å²	121	113.5 Å²	113.5	79%	0.786	79%	0.785	S	S	*	*	P	Polyproline II helix	trans	-66	138.1	-178.3	25.7	-32.8	0	0	0	111.9
42	A	57.3	Low	55.6	Low	92 Å²	92	111.3 Å²	111.3	76%	0.76	78%	0.783	S	S	*	*	P	Polyproline II helix	trans	-61.3	139.8	179.1	0	0	0	0	0	112.3
43	P	65.7	Low	55	Low	116 Å²	116	112.6 Å²	112.6	75%	0.753	79%	0.791	S	S	*	*	P	Polyproline II helix	trans	-72.1	147.3	165	30.2	-32.7	0	0	0	110.5	A45	P43-A45 PolarHBondContact O-N 3.2Å
44	P	60.7	Low	55.1	Low	128 Å²	128	111 Å²	111	83%	0.831	79%	0.788	S	S	*	*	P	Polyproline II helix	trans	-64.5	134.3	179.8	26.2	-33.4	0	0	0	111.4	G46	P44-G46 PolarHBondContact O-N 2.77Å; P44-G46 VanDerWaalsContact O-N 3.16Å
45	A	57.9	Low	54.9	Low	106 Å²	106	111 Å²	111	88%	0.876	79%	0.785	S	S	*	*			trans	-57.4	111.6	175	0	0	0	0	0	111.3	P43	P43-A45 PolarHBondContact O-N 3.2Å
46	G	55.4	Low	54.7	Low	60 Å²	60	115.3 Å²	115.3	62%	0.619	79%	0.793	S	S	*	*	P	Polyproline II helix	trans	-86	147.5	162.1	0	0	0	0	0	110.4	P44	P44-G46 PolarHBondContact O-N 2.77Å; P44-G46 VanDerWaalsContact O-N 3.16Å
47	P	56.8	Low	55.1	Low	131 Å²	131	116.2 Å²	116.2	85%	0.851	80%	0.8	S	S	*	*	P	Polyproline II helix	trans	-69.5	134.2	-171.3	27.4	-33.4	0	0	0	112.5
48	S	55.3	Low	54.9	Low	113 Å²	113	114.8 Å²	114.8	79%	0.79	80%	0.796	S	S	*	*	P	Polyproline II helix	trans	-52.2	130.8	173.6	-52.5	0	0	0	0	113
49	P	52.7	Low	54.9	Low	125 Å²	125	120 Å²	120	81%	0.812	80%	0.802	S	S	*	*	P	Polyproline II helix	trans	-79.5	119.3	156.9	30.2	-27.2	0	0	0	108.5
50	G	57	Low	54.8	Low	62 Å²	62	120.4 Å²	120.4	64%	0.639	80%	0.804	S	S	*	*	P	Polyproline II helix	trans	-64.3	165.5	178.1	0	0	0	0	0	113.6	G52	G50-G52 PolarHBondContact O-N 2.95Å
51	P	57.4	Low	54.2	Low	144 Å²	144	115.9 Å²	115.9	94%	0.935	80%	0.798	S	S	*	*	P	Polyproline II helix	trans	-80.5	118.1	177	31.5	-29.9	0	0	0	110.9
52	G	46.5	Very low	53.8	Low	68 Å²	68	119.3 Å²	119.3	70%	0.701	80%	0.803	S	S	*	*			trans	177.7	134.3	166.9	0	0	0	0	0	108.7	G50	G50-G52 PolarHBondContact O-N 2.95Å
53	P	51.2	Low	52.9	Low	135 Å²	135	122.4 Å²	122.4	88%	0.877	81%	0.807	S	S	*	*				-132.6	168.5	52.7	30.3	-9.9	0	0	0	114.8
54	A	58.8	Low	52.6	Low	87 Å²	87	122.2 Å²	122.2	72%	0.719	81%	0.806	S	S	*	*			trans	-47.5	151.6	178.4	0	0	0	0	0	114.8
55	P	53.4	Low	51.4	Low	116 Å²	116	119.6 Å²	119.6	75%	0.753	80%	0.802	S	S	*	*			trans	-66.9	134.8	167.1	29.7	-32.7	0	0	0	109.4	A57	P55-A57 VanDerWaalsContact C-N 3.32Å; P55-A57 PolarHBondContact O-N 2.91Å
56	F	52	Low	51.3	Low	202 Å²	202	120.4 Å²	120.4	89%	0.886	80%	0.798	S	S	*	*			trans	-59	98.6	162.1	51.8	-83.9	0	0	0	107.8
57	A	51.7	Low	50.9	Low	101 Å²	101	122.1 Å²	122.1	84%	0.835	81%	0.807	S	S	*	*			trans	-77.9	128.8	162.5	0	0	0	0	0	107.6	P55	P55-A57 VanDerWaalsContact C-N 3.32Å; P55-A57 PolarHBondContact O-N 2.91Å
58	G	47.6	Very low	51	Low	74 Å²	74	121.7 Å²	121.7	76%	0.763	80%	0.804	S	S	*	*			trans	118.4	74.6	162.4	0	0	0	0	0	115.3
59	F	51.8	Low	51.1	Low	200 Å²	200	121.6 Å²	121.6	88%	0.877	80%	0.8	S	S	*	*			trans	-144.2	64.7	148.9	-167.5	-102.1	0	0	0	111.1
60	L	51.1	Low	51.1	Low	179 Å²	179	121 Å²	121	94%	0.937	80%	0.799	S	S	*	*	S	Bend	trans	-145.8	108.5	150.7	-73.5	-179.5	0	0	0	106.9
61	G	45.4	Very low	51.1	Low	73 Å²	73	123.6 Å²	123.6	75%	0.753	81%	0.805	S	S	*	*			trans	148.3	112.6	168.1	0	0	0	0	0	115.3
62	Q	43.5	Very low	50.5	Low	194 Å²	194	121.9 Å²	121.9	91%	0.907	80%	0.803	S	S	*	*			trans	99	122.7	152.3	-115.6	86.3	80.7	0	0	120.5
63	D	39.2	Very low	50.3	Low	156 Å²	156	122.4 Å²	122.4	83%	0.834	81%	0.808	S	S	*	*			trans	-48.1	168.9	170.8	-153.1	-123.1	0	0	0	115.5
64	P	60.3	Low	50.3	Low	113 Å²	113	124.8 Å²	124.8	73%	0.734	81%	0.813	S	S	*	*			trans	-92.4	156.9	-159.3	38	-31.2	0	0	0	114.3
65	G	35.5	Very low	49.4	Very low	72 Å²	72	124.2 Å²	124.2	74%	0.742	82%	0.815	S	S	*	*			trans	-165.7	147.1	168.1	0	0	0	0	0	112.6
66	P	55.4	Low	49.3	Very low	124 Å²	124	124.3 Å²	124.3	81%	0.805	82%	0.819	S	S	*	*			trans	-110.2	142.7	-144	36	-25	0	0	0	115.9
67	A	47.2	Very low	49.3	Very low	96 Å²	96	120.9 Å²	120.9	79%	0.793	82%	0.817	S	S	*	*			trans	55	169.5	142.1	0	0	0	0	0	120.9
68	P	58.3	Low	49.1	Very low	122 Å²	122	120.2 Å²	120.2	79%	0.792	81%	0.811	S	S	*	*			cis	-131.7	-141.1	-33.1	30.2	-4.7	0	0	0	111.8
69	P	57.6	Low	49.7	Very low	110 Å²	110	122.7 Å²	122.7	71%	0.714	81%	0.814	S	S	*	*				-126.8	172.3	-96	41.8	-24	0	0	0	118.1
70	S	52.3	Low	49.8	Very low	112 Å²	112	119 Å²	119	78%	0.783	81%	0.81	S	S	*	*			trans	76.7	172.8	148.6	-62.2	0	0	0	0	120.9
71	P	57.5	Low	50	Low	117 Å²	117	120.8 Å²	120.8	76%	0.76	81%	0.81	S	S	*	*				-135.4	-175.6	-60	40.5	-23.7	0	0	0	113.3
72	A	44.5	Very low	50.4	Low	108 Å²	108	120.9 Å²	120.9	89%	0.893	81%	0.811	S	S	*	*			trans	90.4	125.7	157.4	0	0	0	0	0	119.7
73	G	42.2	Very low	50.4	Low	79 Å²	79	116.5 Å²	116.5	81%	0.814	81%	0.808	S	S	*	*			trans	-178.2	80.8	172	0	0	0	0	0	111
74	L	51.8	Low	51.1	Low	185 Å²	185	112.7 Å²	112.7	97%	0.969	80%	0.798	S	S	*	*			trans	-49	138.6	177.7	-72.5	139.2	0	0	0	113.9
75	G	39.3	Very low	51	Low	75 Å²	75	112.2 Å²	112.2	77%	0.773	80%	0.803	S	S	*	*			trans	168.8	80.5	166.2	0	0	0	0	0	115.6
76	S	51.8	Low	51.8	Low	119 Å²	119	114.3 Å²	114.3	83%	0.832	80%	0.804	S	S	*	*			trans	-132.4	137.7	151.3	-77.3	0	0	0	0	105.5
77	P	52.1	Low	51.8	Low	130 Å²	130	113.5 Å²	113.5	84%	0.844	80%	0.802	S	S	*	*				-153.2	132.9	70	36	-14.7	0	0	0	115.9
78	A	47.4	Very low	52.3	Low	86 Å²	86	113.3 Å²	113.3	71%	0.711	80%	0.8	S	S	*	*			trans	-159.3	124.3	151.3	0	0	0	0	0	109.8	P80	A78-P80 WeakPolarHBondContact O-CD 3.28Å
79	P	59.7	Low	52.5	Low	126 Å²	126	113.1 Å²	113.1	82%	0.818	80%	0.801	S	S	*	*			trans	-81	113.6	169	30.3	-29.1	0	0	0	109.5	K81	P79-K81 PolarHBondContact O-N 2.76Å; P79-K81 VanDerWaalsContact O-N 3.14Å
80	P	54.3	Low	52.8	Low	123 Å²	123	116.4 Å²	116.4	80%	0.799	81%	0.807	S	S	*	*			trans	-68.6	113.5	162.1	27.5	-31	0	0	0	108.7	A78 G82	A78-P80 WeakPolarHBondContact O-CD 3.28Å; P80-G82 PolarHBondContact O-N 3.48Å
81	K	55.3	Low	53.9	Low	217 Å²	217	122 Å²	122	94%	0.943	81%	0.811	S	S	*	*	S	Bend	trans	-40.2	120.2	161.6	-174.9	168.7	-179.5	172.1	0	110.4	P79	P79-K81 PolarHBondContact O-N 2.76Å; P79-K81 VanDerWaalsContact O-N 3.14Å
82	G	52.8	Low	54.8	Low	74 Å²	74	125.7 Å²	125.7	76%	0.763	81%	0.81	S	S	*	*			trans	124.7	49.1	172.6	0	0	0	0	0	114.6	P80 A84	P80-G82 PolarHBondContact O-N 3.48Å; G82-A84 PolarHBondContact O-N 3.44Å; G82-A84 VanDerWaalsContact O-N 3.1Å
83	A	44.1	Very low	56.6	Low	102 Å²	102	129.6 Å²	129.6	84%	0.843	81%	0.807	S	S	*	*			trans	-72.1	106.3	169.8	0	0	0	0	0	110.2
84	A	53.2	Low	58.7	Low	76 Å²	76	136.9 Å²	136.9	63%	0.628	81%	0.81	S	S	*	*			trans	65.5	100.7	138.9	0	0	0	0	0	117.2	G82 P86	G82-A84 PolarHBondContact O-N 3.44Å; G82-A84 VanDerWaalsContact O-N 3.1Å; A84-P86 VanDerWaalsContact O-CD 3.28Å; A84-P86 WeakPolarHBondContact O-CD 3.45Å
85	A	58.8	Low	60.5	Low	103 Å²	103	129.8 Å²	129.8	85%	0.851	77%	0.774	S	S	*	*				-71.5	118.5	126.9	0	0	0	0	0	108.3
86	P	51.3	Low	63	Low	116 Å²	116	131.4 Å²	131.4	75%	0.753	77%	0.773	S	S	*	*			trans	-112.5	78	162.8	37.3	-23.9	0	0	0	108.3	A84	A84-P86 VanDerWaalsContact O-CD 3.28Å; A84-P86 WeakPolarHBondContact O-CD 3.45Å
87	S	57.1	Low	65	Low	108 Å²	108	128.2 Å²	128.2	76%	0.755	74%	0.744	S	S	*	*			trans	-123.1	51.2	149.8	73.4	0	0	0	0	108.8	S89	S87-S89 VanDerWaalsContact C-N 3.26Å; S87-S89 PolarHBondContact O-N 3.06Å
88	A	57.5	Low	67	Low	92 Å²	92	125 Å²	125	76%	0.76	73%	0.725	S	S	*	*			trans	-54.8	103	152.7	0	0	0	0	0	105.8	Q90	A88-Q90 PolarHBondContact O-N 3.48Å
89	S	61.4	Low	69.3	Low	117 Å²	117	124.2 Å²	124.2	82%	0.818	72%	0.719	S	S	*	*			trans	-30.7	96.1	179.9	-74.9	0	0	0	0	111.3	S87 R91	S87-S89 VanDerWaalsContact C-N 3.26Å; S87-S89 PolarHBondContact O-N 3.06Å; S89-R91 PolarHBondContact O-N 3.21Å
90	Q	63.8	Low	70.8	Confident	179 Å²	179	123.3 Å²	123.3	84%	0.836	70%	0.704	S	S	*	*			trans	-68.7	93.8	177.8	-173.1	168.2	-11.8	0	0	106	A88 R92	A88-Q90 PolarHBondContact O-N 3.48Å; Q90-R92 PolarHBondContact O-N 3.05Å
91	R	75.2	Confident	72.8	Confident	229 Å²	229	119.4 Å²	119.4	86%	0.864	68%	0.675	S	S	*	*			trans	-51.7	113.4	-179	-172.6	174.5	175.2	-141.5	2.7	107.3	S89 K93	S89-R91 PolarHBondContact O-N 3.21Å; R91-K93 PolarHBondContact O-N 2.99Å
92	R	76.7	Confident	74.7	Confident	195 Å²	195	111.9 Å²	111.9	74%	0.736	65%	0.645	S	S	*	*	P	Polyproline II helix	trans	-50.1	127.6	-178.5	-74.1	-174.5	-91.8	173.6	-7	108.5	Q90 R94	Q90-R92 PolarHBondContact O-N 3.05Å; R92-R94 PolarHBondContact O-N 3.34Å
93	K	82.1	Confident	76.7	Confident	190 Å²	190	114.2 Å²	114.2	83%	0.826	64%	0.636	S	S	*	*	P	Polyproline II helix	trans	-49.8	133.5	178.5	-68.1	-179.1	179.9	179.4	0	109	R91 T95	R91-K93 PolarHBondContact O-N 2.99Å; K93-T95 PolarHBondContact O-N 2.78Å
94	R	87.8	Confident	79.1	Confident	233 Å²	233	109.8 Å²	109.8	88%	0.879	60%	0.597	S	S	*	*	P	Polyproline II helix	trans	-72.1	129.5	-177.1	-174.5	177.1	-179.8	175.1	-0.1	109.1	R92	R92-R94 PolarHBondContact O-N 3.34Å
95	T	89.4	Confident	81.1	Confident	35 Å²	35	106.1 Å²	106.1	22%	0.215	57%	0.568	C	S	.	*	P	Polyproline II helix	trans	-75.5	131.2	171.2	-52.1	0	0	0	0	109.6	K93 L129 R133	K93-T95 PolarHBondContact O-N 2.78Å; T95-L129 HydrophobicContact CG2-CD2 3.8Å; T95-R133 HydrophobicContact CG2-CG 4.34Å; T95-R133 WeakPolarHBondContact OG1-CD 3.38Å; T95-R133 PolarHBondContact OG1-NE 2.97Å
96	S	91.8	Very high	82.9	Confident	109 Å²	109	104.9 Å²	104.9	76%	0.762	54%	0.544	S	S	*	.	P	Polyproline II helix	trans	-103	137.3	167.9	-166.3	0	0	0	0	108.6
97	F	92.6	Very high	84.9	Confident	52 Å²	52	102 Å²	102	23%	0.228	52%	0.522	C	S	.	.	P	Polyproline II helix	trans	-99.6	135.5	179.2	-61.4	-93.7	0	0	0	109.2	L102 L105 L129 W137	F97-L102 HydrophobicContact CB-CD1 4.37Å; F97-L102 HydrophobicContact CB-CD2 3.68Å; F97-L102 HydrophobicContact CB-CG 3.79Å; F97-L102 HydrophobicContact CG-CD2 4.06Å; F97-L105 HydrophobicContact CD1-CD1 4.03Å; F97-L105 HydrophobicContact CE1-CD1 4.09Å; F97-L129 HydrophobicContact CD1-CD1 3.34Å; F97-L129 HydrophobicContact CE1-CD1 3.37Å; F97-L129 HydrophobicContact CG-CD1 4.48Å; F97-W137 HydrophobicContact CE1-CB 4.34Å; F97-W137 AromaticContact CE1-CD1 3.94Å; F97-W137 HydrophobicContact CE1-CG 4.38Å; F97-W137 AromaticContact CE2-CD1 3.77Å; F97-W137 HydrophobicContact CZ-CB 3.94Å; F97-W137 AromaticContact CZ-CD1 3.69Å; F97-W137 HydrophobicContact CZ-CG 4.17Å
98	S	95.8	Very high	86.7	Confident	63 Å²	63	97 Å²	97	44%	0.441	49%	0.487	S	S	.	.	P	Polyproline II helix	trans	-67.6	157.4	167.7	-179	0	0	0	0	110.7	E100 Q101 L102	S98-E100 VanDerWaalsContact C-N 3.3Å; S98-E100 PolarHBondContact O-N 3.37Å; S98-Q101 PolarHBondContact O-N 2.89Å; S98-L102 WeakPolarHBondContact O-CG 3.42Å; S98-L102 PolarHBondContact O-N 3.49Å
99	A	93.9	Very high	88.5	Confident	69 Å²	69	93.4 Å²	93.4	57%	0.57	45%	0.454	S	S	*	.	H	α-helix	trans	-58.4	-42.3	177.4	0	0	0	0	0	112	L102 Q103	A99-L102 WeakPolarHBondContact O-CB 3.19Å; A99-L102 PolarHBondContact O-N 3.38Å; A99-Q103 WeakPolarHBondContact O-CG 3.25Å; A99-Q103 PolarHBondContact O-N 2.89Å
100	E	92.9	Very high	90	Very high	108 Å²	108	98 Å²	98	51%	0.505	45%	0.453	S	S	.	.	H	α-helix	trans	-62.7	-44.7	177.9	-175.9	-178.1	-171.7	0	0	112.1	S98 L102 Q103 L104	S98-E100 VanDerWaalsContact C-N 3.3Å; S98-E100 PolarHBondContact O-N 3.37Å; E100-L102 VanDerWaalsContact C-N 3.29Å; E100-L102 PolarHBondContact O-N 3.47Å; E100-Q103 WeakPolarHBondContact O-CB 3.49Å; E100-Q103 PolarHBondContact O-N 3.49Å; E100-Q103 VanDerWaalsContact O-N 3.14Å; E100-L104 PolarHBondContact O-N 3.33Å; E100-L104 VanDerWaalsContact O-N 3.08Å
101	Q	94.9	Very high	91.3	Very high	41 Å²	41	97.4 Å²	97.4	19%	0.192	44%	0.443	C	S	.	.	H	α-helix	trans	-59.9	-41.4	175.8	-66	169.7	-23.3	0	0	111.1	S98 L105 T127	S98-Q101 PolarHBondContact O-N 2.89Å; Q101-L105 WeakPolarHBondContact O-CB 3.42Å; Q101-L105 WeakPolarHBondContact O-CD1 3.41Å; Q101-L105 WeakPolarHBondContact O-CG 3.34Å; Q101-L105 PolarHBondContact O-N 2.76Å; Q101-T127 HydrophobicContact CB-CG2 4.25Å; Q101-T127 HydrophobicContact CG-CG2 4.21Å; Q101-T127 PolarHBondContact NE2-O 3.47Å
102	L	96.3	Very high	92.2	Very high	59 Å²	59	88.7 Å²	88.7	31%	0.309	42%	0.416	S	S	.	.	H	α-helix	trans	-65.1	-39.7	176.4	-68.7	174.8	0	0	0	112	F97 S98 A99 E100 L105 E106 W137	F97-L102 HydrophobicContact CB-CD1 4.37Å; F97-L102 HydrophobicContact CB-CD2 3.68Å; F97-L102 HydrophobicContact CB-CG 3.79Å; F97-L102 HydrophobicContact CG-CD2 4.06Å; S98-L102 WeakPolarHBondContact O-CG 3.42Å; S98-L102 PolarHBondContact O-N 3.49Å; A99-L102 WeakPolarHBondContact O-CB 3.19Å; A99-L102 PolarHBondContact O-N 3.38Å; E100-L102 VanDerWaalsContact C-N 3.29Å; E100-L102 PolarHBondContact O-N 3.47Å; L102-L105 PolarHBondContact O-N 3.37Å; L102-E106 VanDerWaalsContact O-CB 3.31Å; L102-E106 WeakPolarHBondContact O-CB 3.11Å; L102-E106 VanDerWaalsContact O-CG 3.28Å; L102-E106 WeakPolarHBondContact O-CG 3.21Å; L102-E106 PolarHBondContact O-N 3.44Å; L102-W137 HydrophobicContact CD2-CZ2 4.29Å
103	Q	94.1	Very high	93	Very high	123 Å²	123	84.7 Å²	84.7	58%	0.575	40%	0.401	S	S	*	.	H	α-helix	trans	-60.9	-47.2	177.5	-73.1	173	-9.1	0	0	111.6	A99 E100 E106 L107	A99-Q103 WeakPolarHBondContact O-CG 3.25Å; A99-Q103 PolarHBondContact O-N 2.89Å; E100-Q103 WeakPolarHBondContact O-CB 3.49Å; E100-Q103 PolarHBondContact O-N 3.49Å; E100-Q103 VanDerWaalsContact O-N 3.14Å; Q103-E106 PolarHBondContact O-N 3.28Å; Q103-L107 WeakPolarHBondContact O-CB 3.36Å; Q103-L107 PolarHBondContact O-N 3.16Å
104	L	93.6	Very high	93.7	Very high	8 Å²	8	82.3 Å²	82.3	4%	0.042	39%	0.387	C	S	.	.	H	α-helix	trans	-60.8	-47.3	176.8	179.1	60.7	0	0	0	111.5	E100 E106 L107 V108 L123 L126 T127 I229 F233	E100-L104 PolarHBondContact O-N 3.33Å; E100-L104 VanDerWaalsContact O-N 3.08Å; L104-E106 VanDerWaalsContact C-N 3.33Å; L104-E106 PolarHBondContact O-N 3.05Å; L104-L107 WeakPolarHBondContact O-CB 3.42Å; L104-L107 PolarHBondContact O-N 3.1Å; L104-V108 PolarHBondContact O-N 3.48Å; L104-V108 VanDerWaalsContact O-N 3.09Å; L104-L123 HydrophobicContact CD1-CD2 4.35Å; L104-L123 HydrophobicContact CD2-CD2 3.9Å; L104-L123 HydrophobicContact CG-CD2 3.84Å; L104-L126 HydrophobicContact CD2-CB 4.12Å; L104-L126 HydrophobicContact CD2-CD1 4.31Å; L104-T127 HydrophobicContact CD2-CG2 3.96Å; L104-I229 HydrophobicContact CD1-CG2 3.64Å; L104-F233 HydrophobicContact CD1-CB 4.41Å; L104-F233 HydrophobicContact CD1-CD1 4.35Å; L104-F233 HydrophobicContact CD1-CD2 3.79Å; L104-F233 HydrophobicContact CD1-CE2 4.09Å; L104-F233 HydrophobicContact CD1-CG 3.93Å; L104-F233 HydrophobicContact CD1-CZ 4.49Å
105	L	95.8	Very high	94	Very high	0 Å²	0	71.5 Å²	71.5	0%	0	35%	0.348	C	S	.	.	H	α-helix	trans	-62.6	-39.6	178.5	-70	170.3	0	0	0	112.4	F97 Q101 L102 F109 L123 I134 W137 F138	F97-L105 HydrophobicContact CD1-CD1 4.03Å; F97-L105 HydrophobicContact CE1-CD1 4.09Å; Q101-L105 WeakPolarHBondContact O-CB 3.42Å; Q101-L105 WeakPolarHBondContact O-CD1 3.41Å; Q101-L105 WeakPolarHBondContact O-CG 3.34Å; Q101-L105 PolarHBondContact O-N 2.76Å; L102-L105 PolarHBondContact O-N 3.37Å; L105-F109 VanDerWaalsContact O-CB 3.32Å; L105-F109 WeakPolarHBondContact O-CB 3.16Å; L105-F109 PolarHBondContact O-N 3.25Å; L105-L123 HydrophobicContact CD2-CD1 4.33Å; L105-I134 HydrophobicContact CD2-CD1 3.77Å; L105-I134 HydrophobicContact CD2-CG2 3.96Å; L105-W137 HydrophobicContact CB-CD2 4.15Å; L105-W137 HydrophobicContact CB-CE3 3.96Å; L105-W137 HydrophobicContact CB-CH2 3.56Å; L105-W137 HydrophobicContact CB-CZ2 3.73Å; L105-W137 HydrophobicContact CB-CZ3 3.68Å; L105-W137 HydrophobicContact CD1-CD2 3.92Å; L105-W137 HydrophobicContact CD1-CE3 4.36Å; L105-W137 HydrophobicContact CD1-CG 4.05Å; L105-W137 HydrophobicContact CD2-CE3 4.43Å; L105-F138 HydrophobicContact CD2-CE2 3.78Å
106	E	96.2	Very high	94.2	Very high	77 Å²	77	74.4 Å²	74.4	36%	0.36	36%	0.362	S	S	.	.	H	α-helix	trans	-69.9	-37	176	-74.4	-167.9	156.7	0	0	112.5	L102 Q103 L104 F109 R110 W137 R141	L102-E106 VanDerWaalsContact O-CB 3.31Å; L102-E106 WeakPolarHBondContact O-CB 3.11Å; L102-E106 VanDerWaalsContact O-CG 3.28Å; L102-E106 WeakPolarHBondContact O-CG 3.21Å; L102-E106 PolarHBondContact O-N 3.44Å; Q103-E106 PolarHBondContact O-N 3.28Å; L104-E106 VanDerWaalsContact C-N 3.33Å; L104-E106 PolarHBondContact O-N 3.05Å; E106-F109 WeakPolarHBondContact O-CB 3.45Å; E106-F109 PolarHBondContact O-N 3.06Å; E106-R110 WeakPolarHBondContact O-CG 3.39Å; E106-R110 PolarHBondContact O-N 2.93Å; E106-W137 HydrophobicContact CG-CH2 3.83Å; E106-W137 HydrophobicContact CG-CZ2 3.86Å; E106-R141 IonicContact OE1-CZ 3.51Å; E106-R141 IonicContact OE1-NH1 2.97Å; E106-R141 PolarHBondContact OE1-NH1 3.37Å; E106-R141 IonicContact OE1-NH2 3.34Å
107	L	93.9	Very high	94.4	Very high	55 Å²	55	72 Å²	72	29%	0.288	34%	0.34	S	S	.	.	H	α-helix	trans	-57.8	-54	174.5	-178.6	65.6	0	0	0	110	Q103 L104 F109 R110 W225 I229 F233	Q103-L107 WeakPolarHBondContact O-CB 3.36Å; Q103-L107 PolarHBondContact O-N 3.16Å; L104-L107 WeakPolarHBondContact O-CB 3.42Å; L104-L107 PolarHBondContact O-N 3.1Å; L107-F109 VanDerWaalsContact C-N 3.3Å; L107-F109 PolarHBondContact O-N 3.18Å; L107-R110 WeakPolarHBondContact O-CB 3.44Å; L107-R110 PolarHBondContact O-N 2.88Å; L107-R110 VanDerWaalsContact O-N 3.16Å; L107-W225 HydrophobicContact CD1-CZ2 4.32Å; L107-W225 HydrophobicContact CG-CH2 4.43Å; L107-W225 HydrophobicContact CG-CZ2 4.35Å; L107-W225 WeakPolarHBondContact O-CH2 3.32Å; L107-I229 HydrophobicContact CD2-CD1 4.33Å; L107-I229 HydrophobicContact CD2-CG1 4.02Å; L107-I229 HydrophobicContact CD2-CG2 4.1Å; L107-I229 HydrophobicContact CG-CD1 4.41Å; L107-F233 HydrophobicContact CD2-CE2 3.94Å
108	V	94.7	Very high	94.4	Very high	2 Å²	2	75.1 Å²	75.1	1%	0.012	36%	0.355	C	S	.	.	H	α-helix	trans	-59.2	-42.9	177.1	176.8	0	0	0	0	111.1	L104 R110 R111 T112 L119 L123 F138 I229	L104-V108 PolarHBondContact O-N 3.48Å; L104-V108 VanDerWaalsContact O-N 3.09Å; V108-R110 VanDerWaalsContact C-N 3.26Å; V108-R110 PolarHBondContact O-N 2.68Å; V108-R111 PolarHBondContact O-N 3.35Å; V108-T112 HydrophobicContact CG1-CG2 3.91Å; V108-T112 PolarHBondContact O-N 3.06Å; V108-L119 HydrophobicContact CG1-CD2 3.95Å; V108-L123 HydrophobicContact CB-CD1 4.47Å; V108-L123 HydrophobicContact CG1-CD1 4.25Å; V108-L123 HydrophobicContact CG2-CD1 4.28Å; V108-L123 HydrophobicContact CG2-CD2 4.03Å; V108-F138 HydrophobicContact CB-CZ 4.26Å; V108-F138 HydrophobicContact CG1-CZ 4Å; V108-I229 HydrophobicContact CG2-CD1 4.3Å; V108-I229 HydrophobicContact CG2-CG2 4.44Å
109	F	95.2	Very high	94.2	Very high	17 Å²	17	72.6 Å²	72.6	8%	0.075	34%	0.336	C	S	.	.	H	α-helix	trans	-58.8	-34.7	178.7	-175.8	-93.3	0	0	0	113.7	L105 E106 L107 R111 T112 R113 W137 F138 R141 R142	L105-F109 VanDerWaalsContact O-CB 3.32Å; L105-F109 WeakPolarHBondContact O-CB 3.16Å; L105-F109 PolarHBondContact O-N 3.25Å; E106-F109 WeakPolarHBondContact O-CB 3.45Å; E106-F109 PolarHBondContact O-N 3.06Å; L107-F109 VanDerWaalsContact C-N 3.3Å; L107-F109 PolarHBondContact O-N 3.18Å; F109-R111 PolarHBondContact O-N 3.3Å; F109-T112 WeakPolarHBondContact CA-O 3.39Å; F109-R113 HydrophobicContact CD2-CB 4.46Å; F109-R113 HydrophobicContact CD2-CG 4.46Å; F109-R113 HydrophobicContact CE1-CG 4.14Å; F109-R113 HydrophobicContact CE2-CB 3.95Å; F109-R113 HydrophobicContact CE2-CG 3.98Å; F109-R113 HydrophobicContact CZ-CB 4.22Å; F109-R113 HydrophobicContact CZ-CG 3.81Å; F109-W137 HydrophobicContact CB-CH2 4.42Å; F109-W137 HydrophobicContact CB-CZ3 4.3Å; F109-F138 HydrophobicContact CB-CE1 3.98Å; F109-F138 AromaticContact CD2-CD1 3.81Å; F109-F138 HydrophobicContact CD2-CD1 3.81Å; F109-F138 AromaticContact CD2-CE1 3.9Å; F109-F138 HydrophobicContact CD2-CE1 3.9Å; F109-F138 HydrophobicContact CG-CE1 4.47Å; F109-R141 HydrophobicContact CD1-CG 3.94Å; F109-R141 HydrophobicContact CD2-CB 4.23Å; F109-R141 HydrophobicContact CD2-CG 3.54Å; F109-R141 HydrophobicContact CE1-CG 3.88Å; F109-R141 HydrophobicContact CE2-CB 4.05Å; F109-R141 HydrophobicContact CE2-CG 3.47Å; F109-R141 VanDerWaalsContact CE2-CG 3.47Å; F109-R141 HydrophobicContact CG-CG 3.78Å; F109-R141 HydrophobicContact CZ-CG 3.65Å; F109-R142 HydrophobicContact CE2-CG 3.74Å; F109-R142 HydrophobicContact CZ-CG 4.28Å
110	R	93.9	Very high	94.3	Very high	214 Å²	214	71.4 Å²	71.4	81%	0.808	32%	0.317	S	S	*	.	H	α-helix	trans	-63.9	-21.9	177.9	-74	172.1	66.4	177.4	0.4	112.6	E106 L107 V108	E106-R110 WeakPolarHBondContact O-CG 3.39Å; E106-R110 PolarHBondContact O-N 2.93Å; L107-R110 WeakPolarHBondContact O-CB 3.44Å; L107-R110 PolarHBondContact O-N 2.88Å; L107-R110 VanDerWaalsContact O-N 3.16Å; V108-R110 VanDerWaalsContact C-N 3.26Å; V108-R110 PolarHBondContact O-N 2.68Å
111	R	91.4	Very high	94.5	Very high	166 Å²	166	71 Å²	71	63%	0.626	32%	0.315	S	S	*	.	H	α-helix	trans	-104.4	-47.5	-179.4	-156.9	94.6	166.7	136.3	0.4	113	V108 F109 W225	V108-R111 PolarHBondContact O-N 3.35Å; F109-R111 PolarHBondContact O-N 3.3Å; R111-W225 HydrophobicContact CB-CD2 4.31Å; R111-W225 HydrophobicContact CB-CE3 3.57Å; R111-W225 HydrophobicContact CB-CH2 3.06Å; R111-W225 HydrophobicContact CB-CZ2 3.86Å; R111-W225 HydrophobicContact CB-CZ3 2.9Å; R111-W225 HydrophobicContact CG-CD2 3.76Å; R111-W225 HydrophobicContact CG-CE3 3.24Å; R111-W225 HydrophobicContact CG-CH2 3.64Å; R111-W225 HydrophobicContact CG-CZ2 4.08Å; R111-W225 HydrophobicContact CG-CZ3 3.21Å
112	T	93.3	Very high	94.4	Very high	46 Å²	46	73.9 Å²	73.9	28%	0.282	32%	0.324	S	S	.	.			trans	-125.8	115.4	173.1	-179.7	0	0	0	0	110.2	V108 F109 Y114 P115 L119	V108-T112 HydrophobicContact CG1-CG2 3.91Å; V108-T112 PolarHBondContact O-N 3.06Å; F109-T112 WeakPolarHBondContact CA-O 3.39Å; T112-Y114 PolarHBondContact O-N 3.08Å; T112-Y114 VanDerWaalsContact OG1-C 3.31Å; T112-Y114 PolarHBondContact OG1-N 3.14Å; T112-Y114 PolarHBondContact OG1-O 3.4Å; T112-P115 HydrophobicContact CG2-CB 4.32Å; T112-L119 HydrophobicContact CG2-CD2 3.75Å
113	R	94.3	Very high	94.3	Very high	111 Å²	111	71 Å²	71	42%	0.419	31%	0.31	S	S	.	.	S	Bend	trans	-75.1	-14.5	174	-60.6	-163.3	-60.6	154.7	-0.7	112.2	F109 R142	F109-R113 HydrophobicContact CD2-CB 4.46Å; F109-R113 HydrophobicContact CD2-CG 4.46Å; F109-R113 HydrophobicContact CE1-CG 4.14Å; F109-R113 HydrophobicContact CE2-CB 3.95Å; F109-R113 HydrophobicContact CE2-CG 3.98Å; F109-R113 HydrophobicContact CZ-CB 4.22Å; F109-R113 HydrophobicContact CZ-CG 3.81Å; R113-R142 HydrophobicContact CB-CG 4.49Å; R113-R142 VanDerWaalsContact O-CD 3.3Å; R113-R142 WeakPolarHBondContact O-CD 3.5Å; R113-R142 PolarHBondContact O-NH1 2.91Å
114	Y	95.3	Very high	94.3	Very high	140 Å²	140	66 Å²	66	55%	0.549	29%	0.288	S	S	.	.	S	Bend	trans	-130.3	75.9	-177	-62.5	-84.5	0	0	0	109.2	T112	T112-Y114 PolarHBondContact O-N 3.08Å; T112-Y114 VanDerWaalsContact OG1-C 3.31Å; T112-Y114 PolarHBondContact OG1-N 3.14Å; T112-Y114 PolarHBondContact OG1-O 3.4Å
115	P	93.8	Very high	94.3	Very high	7 Å²	7	68.8 Å²	68.8	5%	0.045	31%	0.313	C	S	.	.			trans	-66.5	140.5	178.7	29.5	-37.5	0	0	0	111	T112 L119 R120 F138	T112-P115 HydrophobicContact CG2-CB 4.32Å; P115-L119 HydrophobicContact CB-CB 4.42Å; P115-L119 HydrophobicContact CB-CD2 3.57Å; P115-L119 HydrophobicContact CB-CG 4.1Å; P115-R120 HydrophobicContact CB-CG 4.02Å; P115-R120 HydrophobicContact CG-CG 3.86Å; P115-R120 PolarHBondContact O-NH1 2.99Å; P115-F138 HydrophobicContact CB-CE1 4.46Å; P115-F138 HydrophobicContact CB-CZ 4.44Å; P115-F138 VanDerWaalsContact CD-CD1 3.42Å; P115-F138 HydrophobicContact CG-CD1 3.58Å; P115-F138 HydrophobicContact CG-CD2 3.85Å; P115-F138 HydrophobicContact CG-CE1 3.61Å; P115-F138 HydrophobicContact CG-CE2 3.88Å; P115-F138 HydrophobicContact CG-CG 3.72Å; P115-F138 HydrophobicContact CG-CZ 3.77Å
116	D	94.9	Very high	94.1	Very high	96 Å²	96	71.8 Å²	71.8	51%	0.513	33%	0.329	S	S	.	.			trans	-68.3	166.7	176.4	-168.8	-95.6	0	0	0	112.5	H118 L119 R120	D116-H118 PolarHBondContact O-N 2.82Å; D116-H118 IonicContact OD1-CD2 3.64Å; D116-H118 PolarHBondContact OD1-N 3.11Å; D116-L119 PolarHBondContact O-N 2.92Å; D116-R120 WeakPolarHBondContact O-CG 3.31Å; D116-R120 PolarHBondContact O-N 2.98Å; D116-R120 PolarHBondContact O-NH1 3.37Å
117	I	95.1	Very high	94	Very high	59 Å²	59	68.4 Å²	68.4	30%	0.303	31%	0.313	S	S	.	.	H	α-helix	trans	-57.3	-46.4	178.4	-177.3	61.3	0	0	0	111.7	L119 R120 E121 E131	I117-L119 VanDerWaalsContact C-N 3.34Å; I117-L119 PolarHBondContact O-N 3.48Å; I117-R120 VanDerWaalsContact CD1-NH2 3.3Å; I117-R120 PolarHBondContact O-N 3.13Å; I117-R120 VanDerWaalsContact O-N 3.12Å; I117-E121 HydrophobicContact CD1-CG 4.38Å; I117-E121 HydrophobicContact CG1-CG 4.49Å; I117-E121 WeakPolarHBondContact O-CG 3.32Å; I117-E121 PolarHBondContact O-N 3.48Å; I117-E131 HydrophobicContact CD1-CG 4.07Å; I117-E131 WeakPolarHBondContact CD1-OE1 3.32Å
118	H	92.9	Very high	94	Very high	116 Å²	116	73.1 Å²	73.1	54%	0.537	34%	0.338	S	S	.	.	H	α-helix	trans	-64.7	-39.8	-178.1	-61.8	-55.7	0	0	0	112.2	D116 R120 E121 R122	D116-H118 PolarHBondContact O-N 2.82Å; D116-H118 IonicContact OD1-CD2 3.64Å; D116-H118 PolarHBondContact OD1-N 3.11Å; H118-R120 VanDerWaalsContact C-N 3.32Å; H118-R120 PolarHBondContact O-N 2.79Å; H118-E121 IonicContact ND1-OE2 2.68Å; H118-E121 PolarHBondContact O-N 3.01Å; H118-R122 PolarHBondContact O-N 3.29Å
119	L	92.2	Very high	94	Very high	10 Å²	10	74 Å²	74	5%	0.052	34%	0.343	C	S	.	.	H	α-helix	trans	-64.2	-38.6	175.8	-179.9	63.5	0	0	0	111.5	V108 T112 P115 D116 I117 L123 E226 F230	V108-L119 HydrophobicContact CG1-CD2 3.95Å; T112-L119 HydrophobicContact CG2-CD2 3.75Å; P115-L119 HydrophobicContact CB-CB 4.42Å; P115-L119 HydrophobicContact CB-CD2 3.57Å; P115-L119 HydrophobicContact CB-CG 4.1Å; D116-L119 PolarHBondContact O-N 2.92Å; I117-L119 VanDerWaalsContact C-N 3.34Å; I117-L119 PolarHBondContact O-N 3.48Å; L119-L123 WeakPolarHBondContact O-CG 3.43Å; L119-L123 PolarHBondContact O-N 3.44Å; L119-L123 VanDerWaalsContact O-N 3.1Å; L119-E226 HydrophobicContact CD1-CG 4.09Å; L119-E226 WeakPolarHBondContact CD1-OE1 3.43Å; L119-E226 WeakPolarHBondContact CD2-OE1 3.37Å; L119-F230 HydrophobicContact CD1-CE2 3.62Å; L119-F230 HydrophobicContact CD1-CZ 3.36Å
120	R	96.3	Very high	94	Very high	45 Å²	45	77 Å²	77	17%	0.17	36%	0.364	C	S	.	.	H	α-helix	trans	-68.5	-36.5	175.5	-67.9	-169.1	-50.1	-89.1	1.3	112.5	P115 D116 I117 H118 L123 A124 E131 I134	P115-R120 HydrophobicContact CB-CG 4.02Å; P115-R120 HydrophobicContact CG-CG 3.86Å; P115-R120 PolarHBondContact O-NH1 2.99Å; D116-R120 WeakPolarHBondContact O-CG 3.31Å; D116-R120 PolarHBondContact O-N 2.98Å; D116-R120 PolarHBondContact O-NH1 3.37Å; I117-R120 VanDerWaalsContact CD1-NH2 3.3Å; I117-R120 PolarHBondContact O-N 3.13Å; I117-R120 VanDerWaalsContact O-N 3.12Å; H118-R120 VanDerWaalsContact C-N 3.32Å; H118-R120 PolarHBondContact O-N 2.79Å; R120-L123 PolarHBondContact O-N 2.82Å; R120-A124 WeakPolarHBondContact O-CB 3.32Å; R120-A124 PolarHBondContact O-N 3.01Å; R120-E131 HydrophobicContact CB-CG 4.02Å; R120-E131 IonicContact CZ-OE1 2.79Å; R120-E131 IonicContact NE-OE1 3.51Å; R120-E131 PolarHBondContact NE-OE1 3.35Å; R120-E131 IonicContact NH2-OE1 3.65Å; R120-E131 PolarHBondContact NH2-OE1 2.83Å; R120-I134 HydrophobicContact CB-CG2 4.27Å; R120-I134 HydrophobicContact CG-CG2 4.13Å
121	E	96	Very high	94.1	Very high	100 Å²	100	69.1 Å²	69.1	47%	0.467	34%	0.336	S	S	.	.	H	α-helix	trans	-64.1	-42.8	175.4	-72.1	176	156.2	0	0	111.8	I117 H118 L123 A124 A125 E131	I117-E121 HydrophobicContact CD1-CG 4.38Å; I117-E121 HydrophobicContact CG1-CG 4.49Å; I117-E121 WeakPolarHBondContact O-CG 3.32Å; I117-E121 PolarHBondContact O-N 3.48Å; H118-E121 IonicContact ND1-OE2 2.68Å; H118-E121 PolarHBondContact O-N 3.01Å; E121-L123 PolarHBondContact O-N 2.68Å; E121-A124 WeakPolarHBondContact O-CB 3.26Å; E121-A124 PolarHBondContact O-N 3.21Å; E121-A125 PolarHBondContact O-N 2.97Å; E121-E131 HydrophobicContact CG-CG 4.43Å
122	R	93.3	Very high	94.3	Very high	100 Å²	100	63.5 Å²	63.5	38%	0.377	32%	0.322	S	S	.	.	H	α-helix	trans	-62.3	-42.2	173.6	-70.1	-176.2	177.7	-158.6	5.5	112.3	H118 A124 A125 L126 E227 F230	H118-R122 PolarHBondContact O-N 3.29Å; R122-A124 VanDerWaalsContact C-N 3.31Å; R122-A124 PolarHBondContact O-N 3.36Å; R122-A125 PolarHBondContact O-N 3.44Å; R122-L126 WeakPolarHBondContact O-CG 3.42Å; R122-L126 PolarHBondContact O-N 3.4Å; R122-E227 IonicContact CZ-OE1 3.68Å; R122-E227 IonicContact NH1-OE1 3.76Å; R122-E227 PolarHBondContact NH1-OE1 3.44Å; R122-E227 IonicContact NH2-OE1 3.81Å; R122-F230 HydrophobicContact CB-CE1 4.23Å; R122-F230 HydrophobicContact CB-CE2 3.9Å; R122-F230 HydrophobicContact CB-CZ 3.63Å; R122-F230 HydrophobicContact CG-CE2 4.4Å
123	L	94	Very high	94.4	Very high	0 Å²	0	64.1 Å²	64.1	0%	0	32%	0.319	C	S	.	.	H	α-helix	trans	-64.1	-35.2	174	-73.4	170.1	0	0	0	112.9	L104 L105 V108 L119 R120 E121 A125 L126 T127 I134 F138 F230	L104-L123 HydrophobicContact CD1-CD2 4.35Å; L104-L123 HydrophobicContact CD2-CD2 3.9Å; L104-L123 HydrophobicContact CG-CD2 3.84Å; L105-L123 HydrophobicContact CD2-CD1 4.33Å; V108-L123 HydrophobicContact CB-CD1 4.47Å; V108-L123 HydrophobicContact CG1-CD1 4.25Å; V108-L123 HydrophobicContact CG2-CD1 4.28Å; V108-L123 HydrophobicContact CG2-CD2 4.03Å; L119-L123 WeakPolarHBondContact O-CG 3.43Å; L119-L123 PolarHBondContact O-N 3.44Å; L119-L123 VanDerWaalsContact O-N 3.1Å; R120-L123 PolarHBondContact O-N 2.82Å; E121-L123 PolarHBondContact O-N 2.68Å; L123-A125 VanDerWaalsContact C-N 3.34Å; L123-L126 PolarHBondContact O-N 3.28Å; L123-T127 WeakPolarHBondContact O-CB 3.25Å; L123-T127 WeakPolarHBondContact O-CG2 3.48Å; L123-T127 PolarHBondContact O-N 3.45Å; L123-T127 PolarHBondContact O-OG1 3.24Å; L123-I134 HydrophobicContact CB-CD1 4.3Å; L123-I134 HydrophobicContact CB-CG2 4.33Å; L123-I134 HydrophobicContact CD1-CG2 4.29Å; L123-F138 HydrophobicContact CD1-CE2 4.14Å; L123-F138 HydrophobicContact CD1-CZ 4.37Å; L123-F230 HydrophobicContact CD2-CE1 3.94Å; L123-F230 HydrophobicContact CG-CE1 4.25Å; L123-F230 HydrophobicContact CG-CZ 4.38Å
124	A	95.1	Very high	94.5	Very high	16 Å²	16	58.8 Å²	58.8	13%	0.132	30%	0.299	C	S	.	.	H	α-helix	trans	-62.6	-43.1	175.3	0	0	0	0	0	111.1	R120 E121 R122 L128 L129 E131 I134	R120-A124 WeakPolarHBondContact O-CB 3.32Å; R120-A124 PolarHBondContact O-N 3.01Å; E121-A124 WeakPolarHBondContact O-CB 3.26Å; E121-A124 PolarHBondContact O-N 3.21Å; R122-A124 VanDerWaalsContact C-N 3.31Å; R122-A124 PolarHBondContact O-N 3.36Å; A124-L128 WeakPolarHBondContact O-CA 3.31Å; A124-L128 PolarHBondContact O-N 3.33Å; A124-L129 WeakPolarHBondContact CA-O 3.27Å; A124-L129 WeakPolarHBondContact CB-O 3.11Å; A124-L129 PolarHBondContact O-N 3.03Å; A124-E131 HydrophobicContact CB-CB 4.34Å; A124-I134 HydrophobicContact CB-CG1 4.35Å
125	A	93.8	Very high	94.6	Very high	68 Å²	68	55.9 Å²	55.9	56%	0.562	29%	0.291	S	S	*	.	H	α-helix	trans	-61.9	-48	174.8	0	0	0	0	0	111.9	E121 R122 L123 L128	E121-A125 PolarHBondContact O-N 2.97Å; R122-A125 PolarHBondContact O-N 3.44Å; L123-A125 VanDerWaalsContact C-N 3.34Å; A125-L128 WeakPolarHBondContact O-CD2 2.99Å; A125-L128 PolarHBondContact O-N 3.39Å
126	L	91.4	Very high	94.8	Very high	63 Å²	63	58.3 Å²	58.3	33%	0.33	31%	0.305	S	S	.	.	H	α-helix	trans	-68.9	-39.2	-178.5	-68.7	174.7	0	0	0	113.6	L104 R122 L123 L128 F230	L104-L126 HydrophobicContact CD2-CB 4.12Å; L104-L126 HydrophobicContact CD2-CD1 4.31Å; R122-L126 WeakPolarHBondContact O-CG 3.42Å; R122-L126 PolarHBondContact O-N 3.4Å; L123-L126 PolarHBondContact O-N 3.28Å; L126-L128 VanDerWaalsContact C-N 3.35Å; L126-F230 HydrophobicContact CD1-CD1 3.2Å; L126-F230 HydrophobicContact CD1-CE1 3.57Å; L126-F230 HydrophobicContact CD1-CG 4.2Å
127	T	92.5	Very high	94.9	Very high	5 Å²	5	54.9 Å²	54.9	3%	0.031	29%	0.285	C	S	.	.	H	α-helix	trans	-86.3	-8	-178.5	60.2	0	0	0	0	113.2	Q101 L104 L123 L129 I134	Q101-T127 HydrophobicContact CB-CG2 4.25Å; Q101-T127 HydrophobicContact CG-CG2 4.21Å; Q101-T127 PolarHBondContact NE2-O 3.47Å; L104-T127 HydrophobicContact CD2-CG2 3.96Å; L123-T127 WeakPolarHBondContact O-CB 3.25Å; L123-T127 WeakPolarHBondContact O-CG2 3.48Å; L123-T127 PolarHBondContact O-N 3.45Å; L123-T127 PolarHBondContact O-OG1 3.24Å; T127-L129 PolarHBondContact O-N 3.12Å; T127-I134 WeakPolarHBondContact OG1-CD1 3.38Å
128	L	94.5	Very high	95	Very high	154 Å²	154	52.2 Å²	52.2	81%	0.806	27%	0.271	S	S	*	.	T	Hydrogen-bonded Turn	trans	55.2	35.7	-172.1	-55.3	176.1	0	0	0	112.8	A124 A125 L126	A124-L128 WeakPolarHBondContact O-CA 3.31Å; A124-L128 PolarHBondContact O-N 3.33Å; A125-L128 WeakPolarHBondContact O-CD2 2.99Å; A125-L128 PolarHBondContact O-N 3.39Å; L126-L128 VanDerWaalsContact C-N 3.35Å
129	L	94.2	Very high	95.2	Very high	21 Å²	21	50.7 Å²	50.7	11%	0.11	27%	0.265	C	S	.	.	S	Bend	trans	-119.1	146.5	178.1	-63.2	177.9	0	0	0	110	T95 F97 A124 T127 I134	T95-L129 HydrophobicContact CG2-CD2 3.8Å; F97-L129 HydrophobicContact CD1-CD1 3.34Å; F97-L129 HydrophobicContact CE1-CD1 3.37Å; F97-L129 HydrophobicContact CG-CD1 4.48Å; A124-L129 WeakPolarHBondContact CA-O 3.27Å; A124-L129 WeakPolarHBondContact CB-O 3.11Å; A124-L129 PolarHBondContact O-N 3.03Å; T127-L129 PolarHBondContact O-N 3.12Å; L129-I134 HydrophobicContact CB-CD1 4.42Å
130	P	95.3	Very high	95.4	Very high	81 Å²	81	55.2 Å²	55.2	53%	0.526	29%	0.289	S	S	.	.			trans	-59.1	143.3	174.6	-21.9	31.5	0	0	0	112	S132 R133 I134	P130-S132 PolarHBondContact O-N 3.38Å; P130-S132 VanDerWaalsContact O-N 3.13Å; P130-R133 HydrophobicContact CB-CG 4.26Å; P130-R133 HydrophobicContact CG-CG 4.22Å; P130-R133 WeakPolarHBondContact O-CA 3.45Å; P130-R133 VanDerWaalsContact O-CB 3.32Å; P130-R133 WeakPolarHBondContact O-CB 3.42Å; P130-R133 PolarHBondContact O-N 3.48Å; P130-I134 PolarHBondContact O-N 2.8Å
131	E	96	Very high	95.5	Very high	47 Å²	47	56.2 Å²	56.2	22%	0.22	29%	0.292	C	S	.	.	H	α-helix	trans	-49.7	-41.9	176.9	-179.5	-82.6	163.8	0	0	111.8	I117 R120 E121 A124 R133 I134 Q135	I117-E131 HydrophobicContact CD1-CG 4.07Å; I117-E131 WeakPolarHBondContact CD1-OE1 3.32Å; R120-E131 HydrophobicContact CB-CG 4.02Å; R120-E131 IonicContact CZ-OE1 2.79Å; R120-E131 IonicContact NE-OE1 3.51Å; R120-E131 PolarHBondContact NE-OE1 3.35Å; R120-E131 IonicContact NH2-OE1 3.65Å; R120-E131 PolarHBondContact NH2-OE1 2.83Å; E121-E131 HydrophobicContact CG-CG 4.43Å; A124-E131 HydrophobicContact CB-CB 4.34Å; E131-R133 PolarHBondContact O-N 3.03Å; E131-R133 VanDerWaalsContact O-N 3.11Å; E131-I134 CarbonylContact O-C 3.58Å; E131-I134 WeakPolarHBondContact O-CA 3.28Å; E131-I134 VanDerWaalsContact O-CB 3.31Å; E131-I134 WeakPolarHBondContact O-CB 3.39Å; E131-I134 PolarHBondContact O-N 2.92Å; E131-Q135 PolarHBondContact O-N 3.43Å
132	S	95.8	Very high	95.5	Very high	48 Å²	48	53.4 Å²	53.4	34%	0.336	28%	0.278	S	S	.	.	H	α-helix	trans	-56	-32.8	176.5	-178.9	0	0	0	0	113	P130 V136	P130-S132 PolarHBondContact O-N 3.38Å; P130-S132 VanDerWaalsContact O-N 3.13Å; S132-V136 VanDerWaalsContact O-CG2 3.27Å; S132-V136 WeakPolarHBondContact O-CG2 3.37Å; S132-V136 PolarHBondContact O-N 3.09Å
133	R	96.3	Very high	95.6	Very high	59 Å²	59	50.2 Å²	50.2	22%	0.223	27%	0.273	C	S	.	.	H	α-helix	trans	-73.7	-39.2	176	-60.6	-61.4	161.7	172	-5.5	112.2	T95 P130 E131 V136 W137	T95-R133 HydrophobicContact CG2-CG 4.34Å; T95-R133 WeakPolarHBondContact OG1-CD 3.38Å; T95-R133 PolarHBondContact OG1-NE 2.97Å; P130-R133 HydrophobicContact CB-CG 4.26Å; P130-R133 HydrophobicContact CG-CG 4.22Å; P130-R133 WeakPolarHBondContact O-CA 3.45Å; P130-R133 VanDerWaalsContact O-CB 3.32Å; P130-R133 WeakPolarHBondContact O-CB 3.42Å; P130-R133 PolarHBondContact O-N 3.48Å; E131-R133 PolarHBondContact O-N 3.03Å; E131-R133 VanDerWaalsContact O-N 3.11Å; R133-V136 PolarHBondContact O-N 3.26Å; R133-W137 VanDerWaalsContact O-CB 3.32Å; R133-W137 WeakPolarHBondContact O-CB 3.31Å; R133-W137 PolarHBondContact O-N 2.85Å
134	I	96.6	Very high	95.7	Very high	0 Å²	0	55.5 Å²	55.5	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-60.2	-49.1	171.6	-51.1	-71.9	0	0	0	109.1	L105 R120 L123 A124 T127 L129 P130 E131 V136 W137 F138	L105-I134 HydrophobicContact CD2-CD1 3.77Å; L105-I134 HydrophobicContact CD2-CG2 3.96Å; R120-I134 HydrophobicContact CB-CG2 4.27Å; R120-I134 HydrophobicContact CG-CG2 4.13Å; L123-I134 HydrophobicContact CB-CD1 4.3Å; L123-I134 HydrophobicContact CB-CG2 4.33Å; L123-I134 HydrophobicContact CD1-CG2 4.29Å; A124-I134 HydrophobicContact CB-CG1 4.35Å; T127-I134 WeakPolarHBondContact OG1-CD1 3.38Å; L129-I134 HydrophobicContact CB-CD1 4.42Å; P130-I134 PolarHBondContact O-N 2.8Å; E131-I134 CarbonylContact O-C 3.58Å; E131-I134 WeakPolarHBondContact O-CA 3.28Å; E131-I134 VanDerWaalsContact O-CB 3.31Å; E131-I134 WeakPolarHBondContact O-CB 3.39Å; E131-I134 PolarHBondContact O-N 2.92Å; I134-V136 PolarHBondContact O-N 3.12Å; I134-W137 WeakPolarHBondContact O-CB 3.36Å; I134-W137 PolarHBondContact O-N 3.4Å; I134-W137 VanDerWaalsContact O-N 3.12Å; I134-F138 HydrophobicContact CG2-CD2 3.76Å; I134-F138 HydrophobicContact CG2-CE2 3.74Å; I134-F138 WeakPolarHBondContact O-CD2 3.32Å; I134-F138 PolarHBondContact O-N 3.27Å
135	Q	96.7	Very high	95.6	Very high	79 Å²	79	56.1 Å²	56.1	37%	0.369	30%	0.299	S	S	.	.	H	α-helix	trans	-56.7	-48.9	178.6	-170.1	-162.7	-19	0	0	112.2	E131 W137 F138 Q139	E131-Q135 PolarHBondContact O-N 3.43Å; Q135-W137 VanDerWaalsContact C-N 3.33Å; Q135-W137 PolarHBondContact O-N 3.06Å; Q135-F138 PolarHBondContact O-N 3.41Å; Q135-Q139 WeakPolarHBondContact O-CG 3.41Å; Q135-Q139 PolarHBondContact O-N 3.5Å; Q135-Q139 PolarHBondContact O-NE2 3.14Å
136	V	97	Very high	95.6	Very high	57 Å²	57	59.8 Å²	59.8	35%	0.345	30%	0.298	S	S	.	.	H	α-helix	trans	-64.7	-38.5	177.5	171.5	0	0	0	0	111.2	S132 R133 I134 Q139 N140	S132-V136 VanDerWaalsContact O-CG2 3.27Å; S132-V136 WeakPolarHBondContact O-CG2 3.37Å; S132-V136 PolarHBondContact O-N 3.09Å; R133-V136 PolarHBondContact O-N 3.26Å; I134-V136 PolarHBondContact O-N 3.12Å; V136-Q139 PolarHBondContact O-N 2.8Å; V136-N140 WeakPolarHBondContact O-CB 3.47Å; V136-N140 VanDerWaalsContact O-CG 3.31Å; V136-N140 PolarHBondContact O-N 3.23Å; V136-N140 PolarHBondContact O-ND2 3.41Å
137	W	97.1	Very high	95.5	Very high	25 Å²	25	66.5 Å²	66.5	10%	0.095	32%	0.319	C	S	.	.	H	α-helix	trans	-60.5	-48.1	176.1	-174.2	100.6	0	0	0	111.4	F97 L102 L105 E106 F109 R133 I134 Q135 Q139 N140 R141	F97-W137 HydrophobicContact CE1-CB 4.34Å; F97-W137 AromaticContact CE1-CD1 3.94Å; F97-W137 HydrophobicContact CE1-CG 4.38Å; F97-W137 AromaticContact CE2-CD1 3.77Å; F97-W137 HydrophobicContact CZ-CB 3.94Å; F97-W137 AromaticContact CZ-CD1 3.69Å; F97-W137 HydrophobicContact CZ-CG 4.17Å; L102-W137 HydrophobicContact CD2-CZ2 4.29Å; L105-W137 HydrophobicContact CB-CD2 4.15Å; L105-W137 HydrophobicContact CB-CE3 3.96Å; L105-W137 HydrophobicContact CB-CH2 3.56Å; L105-W137 HydrophobicContact CB-CZ2 3.73Å; L105-W137 HydrophobicContact CB-CZ3 3.68Å; L105-W137 HydrophobicContact CD1-CD2 3.92Å; L105-W137 HydrophobicContact CD1-CE3 4.36Å; L105-W137 HydrophobicContact CD1-CG 4.05Å; L105-W137 HydrophobicContact CD2-CE3 4.43Å; E106-W137 HydrophobicContact CG-CH2 3.83Å; E106-W137 HydrophobicContact CG-CZ2 3.86Å; F109-W137 HydrophobicContact CB-CH2 4.42Å; F109-W137 HydrophobicContact CB-CZ3 4.3Å; R133-W137 VanDerWaalsContact O-CB 3.32Å; R133-W137 WeakPolarHBondContact O-CB 3.31Å; R133-W137 PolarHBondContact O-N 2.85Å; I134-W137 WeakPolarHBondContact O-CB 3.36Å; I134-W137 PolarHBondContact O-N 3.4Å; I134-W137 VanDerWaalsContact O-N 3.12Å; Q135-W137 VanDerWaalsContact C-N 3.33Å; Q135-W137 PolarHBondContact O-N 3.06Å; W137-Q139 VanDerWaalsContact C-N 3.33Å; W137-Q139 PolarHBondContact O-N 2.95Å; W137-N140 PolarHBondContact O-N 3.36Å; W137-R141 HydrophobicContact CE3-CB 4.15Å; W137-R141 HydrophobicContact CH2-CB 4.2Å; W137-R141 HydrophobicContact CH2-CG 3.9Å; W137-R141 HydrophobicContact CZ3-CB 3.95Å; W137-R141 HydrophobicContact CZ3-CG 3.99Å; W137-R141 VanDerWaalsContact O-CB 3.32Å; W137-R141 WeakPolarHBondContact O-CB 3.34Å; W137-R141 PolarHBondContact O-N 3.43Å
138	F	97.8	Very high	95.3	Very high	2 Å²	2	71.6 Å²	71.6	1%	0.009	34%	0.343	C	S	.	.	H	α-helix	trans	-63.6	-37.5	178.3	-88.6	-88.5	0	0	0	112.3	L105 V108 F109 P115 L123 I134 Q135 R141 R142	L105-F138 HydrophobicContact CD2-CE2 3.78Å; V108-F138 HydrophobicContact CB-CZ 4.26Å; V108-F138 HydrophobicContact CG1-CZ 4Å; F109-F138 HydrophobicContact CB-CE1 3.98Å; F109-F138 AromaticContact CD2-CD1 3.81Å; F109-F138 HydrophobicContact CD2-CD1 3.81Å; F109-F138 AromaticContact CD2-CE1 3.9Å; F109-F138 HydrophobicContact CD2-CE1 3.9Å; F109-F138 HydrophobicContact CG-CE1 4.47Å; P115-F138 HydrophobicContact CB-CE1 4.46Å; P115-F138 HydrophobicContact CB-CZ 4.44Å; P115-F138 VanDerWaalsContact CD-CD1 3.42Å; P115-F138 HydrophobicContact CG-CD1 3.58Å; P115-F138 HydrophobicContact CG-CD2 3.85Å; P115-F138 HydrophobicContact CG-CE1 3.61Å; P115-F138 HydrophobicContact CG-CE2 3.88Å; P115-F138 HydrophobicContact CG-CG 3.72Å; P115-F138 HydrophobicContact CG-CZ 3.77Å; L123-F138 HydrophobicContact CD1-CE2 4.14Å; L123-F138 HydrophobicContact CD1-CZ 4.37Å; I134-F138 HydrophobicContact CG2-CD2 3.76Å; I134-F138 HydrophobicContact CG2-CE2 3.74Å; I134-F138 WeakPolarHBondContact O-CD2 3.32Å; I134-F138 PolarHBondContact O-N 3.27Å; Q135-F138 PolarHBondContact O-N 3.41Å; F138-R141 PolarHBondContact O-N 2.73Å; F138-R142 WeakPolarHBondContact O-CG 3.45Å; F138-R142 PolarHBondContact O-N 2.77Å
139	Q	97.4	Very high	94.5	Very high	85 Å²	85	68.3 Å²	68.3	40%	0.397	33%	0.333	S	S	.	.	H	α-helix	trans	-60.9	-50	172.8	-73.5	174.6	81.4	0	0	111.9	Q135 V136 W137 R141 R142 A143	Q135-Q139 WeakPolarHBondContact O-CG 3.41Å; Q135-Q139 PolarHBondContact O-N 3.5Å; Q135-Q139 PolarHBondContact O-NE2 3.14Å; V136-Q139 PolarHBondContact O-N 2.8Å; W137-Q139 VanDerWaalsContact C-N 3.33Å; W137-Q139 PolarHBondContact O-N 2.95Å; Q139-R141 VanDerWaalsContact C-N 3.31Å; Q139-R141 PolarHBondContact O-N 2.74Å; Q139-R142 PolarHBondContact O-N 3.17Å; Q139-A143 PolarHBondContact O-N 3.46Å
140	N	97.1	Very high	93	Very high	105 Å²	105	69.4 Å²	69.4	56%	0.561	35%	0.349	S	S	*	.	H	α-helix	trans	-62.7	-39.7	178.2	-73.2	-19.9	0	0	0	111.7	V136 W137 A143 K144	V136-N140 WeakPolarHBondContact O-CB 3.47Å; V136-N140 VanDerWaalsContact O-CG 3.31Å; V136-N140 PolarHBondContact O-N 3.23Å; V136-N140 PolarHBondContact O-ND2 3.41Å; W137-N140 PolarHBondContact O-N 3.36Å; N140-A143 PolarHBondContact O-N 3.03Å; N140-K144 PolarHBondContact O-N 2.87Å
141	R	97.2	Very high	91.2	Very high	65 Å²	65	74.5 Å²	74.5	25%	0.245	36%	0.363	C	S	.	.	H	α-helix	trans	-63.5	-45.3	177.9	-176.1	65.7	-166.9	-168.2	-1.5	111.5	E106 F109 W137 F138 Q139 K144 S145	E106-R141 IonicContact OE1-CZ 3.51Å; E106-R141 IonicContact OE1-NH1 2.97Å; E106-R141 PolarHBondContact OE1-NH1 3.37Å; E106-R141 IonicContact OE1-NH2 3.34Å; F109-R141 HydrophobicContact CD1-CG 3.94Å; F109-R141 HydrophobicContact CD2-CB 4.23Å; F109-R141 HydrophobicContact CD2-CG 3.54Å; F109-R141 HydrophobicContact CE1-CG 3.88Å; F109-R141 HydrophobicContact CE2-CB 4.05Å; F109-R141 HydrophobicContact CE2-CG 3.47Å; F109-R141 VanDerWaalsContact CE2-CG 3.47Å; F109-R141 HydrophobicContact CG-CG 3.78Å; F109-R141 HydrophobicContact CZ-CG 3.65Å; W137-R141 HydrophobicContact CE3-CB 4.15Å; W137-R141 HydrophobicContact CH2-CB 4.2Å; W137-R141 HydrophobicContact CH2-CG 3.9Å; W137-R141 HydrophobicContact CZ3-CB 3.95Å; W137-R141 HydrophobicContact CZ3-CG 3.99Å; W137-R141 VanDerWaalsContact O-CB 3.32Å; W137-R141 WeakPolarHBondContact O-CB 3.34Å; W137-R141 PolarHBondContact O-N 3.43Å; F138-R141 PolarHBondContact O-N 2.73Å; Q139-R141 VanDerWaalsContact C-N 3.31Å; Q139-R141 PolarHBondContact O-N 2.74Å; R141-K144 PolarHBondContact O-N 3.16Å; R141-S145 PolarHBondContact O-N 2.79Å
142	R	96.7	Very high	89	Confident	41 Å²	41	76.9 Å²	76.9	16%	0.155	39%	0.385	C	S	.	.	H	α-helix	trans	-62.8	-41.3	174	-72.9	-167.1	-63.4	-92.9	6	112.2	F109 R113 F138 Q139 K144 S145 R146	F109-R142 HydrophobicContact CE2-CG 3.74Å; F109-R142 HydrophobicContact CZ-CG 4.28Å; R113-R142 HydrophobicContact CB-CG 4.49Å; R113-R142 VanDerWaalsContact O-CD 3.3Å; R113-R142 WeakPolarHBondContact O-CD 3.5Å; R113-R142 PolarHBondContact O-NH1 2.91Å; F138-R142 WeakPolarHBondContact O-CG 3.45Å; F138-R142 PolarHBondContact O-N 2.77Å; Q139-R142 PolarHBondContact O-N 3.17Å; R142-K144 PolarHBondContact O-N 3.43Å; R142-S145 PolarHBondContact O-N 3.29Å; R142-R146 PolarHBondContact O-N 3Å
143	A	96.3	Very high	86.9	Confident	34 Å²	34	83.5 Å²	83.5	28%	0.281	41%	0.408	S	S	.	.	H	α-helix	trans	-59.7	-46.6	176.1	0	0	0	0	0	111.3	Q139 N140 S145 R146 R147	Q139-A143 PolarHBondContact O-N 3.46Å; N140-A143 PolarHBondContact O-N 3.03Å; A143-S145 PolarHBondContact O-N 2.79Å; A143-R146 PolarHBondContact O-N 3.43Å; A143-R147 WeakPolarHBondContact O-CG 3.31Å; A143-R147 PolarHBondContact O-N 3.01Å; A143-R147 VanDerWaalsContact O-N 3.13Å
144	K	94.8	Very high	84.6	Confident	111 Å²	111	87.8 Å²	87.8	48%	0.483	43%	0.43	S	S	.	.	H	α-helix	trans	-59.4	-45.3	174.7	-174.6	175.1	177.3	179.1	0	111.7	N140 R141 R142 R146 R147 Q148	N140-K144 PolarHBondContact O-N 2.87Å; R141-K144 PolarHBondContact O-N 3.16Å; R142-K144 PolarHBondContact O-N 3.43Å; K144-R146 PolarHBondContact O-N 3.43Å; K144-R147 PolarHBondContact O-N 3.25Å; K144-Q148 WeakPolarHBondContact O-CG 3.36Å; K144-Q148 PolarHBondContact O-N 3.01Å
145	S	92.8	Very high	82.3	Confident	29 Å²	29	93.9 Å²	93.9	20%	0.203	47%	0.47	C	S	.	.	H	α-helix	trans	-58.8	-45.5	177.7	172.3	0	0	0	0	112.4	R141 R142 A143 R147 Q148 S149	R141-S145 PolarHBondContact O-N 2.79Å; R142-S145 PolarHBondContact O-N 3.29Å; A143-S145 PolarHBondContact O-N 2.79Å; S145-R147 VanDerWaalsContact C-N 3.35Å; S145-R147 PolarHBondContact O-N 3.34Å; S145-Q148 PolarHBondContact O-N 2.96Å; S145-S149 PolarHBondContact O-N 3.31Å; S145-S149 PolarHBondContact O-OG 2.86Å
146	R	94	Very high	80	Confident	144 Å²	144	96.7 Å²	96.7	54%	0.543	49%	0.487	S	S	.	.	H	α-helix	trans	-62.3	-39.7	176.9	-70.3	-166.1	-59.4	-92.8	2.4	112.8	R142 A143 K144 Q148 S149 G150	R142-R146 PolarHBondContact O-N 3Å; A143-R146 PolarHBondContact O-N 3.43Å; K144-R146 PolarHBondContact O-N 3.43Å; R146-Q148 VanDerWaalsContact C-N 3.29Å; R146-Q148 PolarHBondContact O-N 2.93Å; R146-S149 PolarHBondContact O-OG 3.16Å; R146-S149 VanDerWaalsContact O-OG 3.1Å; R146-G150 PolarHBondContact O-N 2.96Å
147	R	90.3	Very high	77.7	Confident	204 Å²	204	99 Å²	99	77%	0.77	51%	0.505	S	S	*	.	H	α-helix	trans	-66.2	-30.9	177.2	-66.8	175.8	77.5	-169.8	4.4	112.6	A143 K144 S145	A143-R147 WeakPolarHBondContact O-CG 3.31Å; A143-R147 PolarHBondContact O-N 3.01Å; A143-R147 VanDerWaalsContact O-N 3.13Å; K144-R147 PolarHBondContact O-N 3.25Å; S145-R147 VanDerWaalsContact C-N 3.35Å; S145-R147 PolarHBondContact O-N 3.34Å
148	Q	87.7	Confident	75.2	Confident	113 Å²	113	107.5 Å²	107.5	53%	0.528	54%	0.538	S	S	.	.	H	α-helix	trans	-82.5	-32	179.4	-70.8	175.6	-4.8	0	0	113.2	K144 S145 R146	K144-Q148 WeakPolarHBondContact O-CG 3.36Å; K144-Q148 PolarHBondContact O-N 3.01Å; S145-Q148 PolarHBondContact O-N 2.96Å; R146-Q148 VanDerWaalsContact C-N 3.29Å; R146-Q148 PolarHBondContact O-N 2.93Å
149	S	77.1	Confident	72.7	Confident	85 Å²	85	112.7 Å²	112.7	59%	0.594	57%	0.572	S	S	*	*	H	α-helix	trans	-75.1	-29.6	178.4	54.3	0	0	0	0	113.1	S145 R146 K151	S145-S149 PolarHBondContact O-N 3.31Å; S145-S149 PolarHBondContact O-OG 2.86Å; R146-S149 PolarHBondContact O-OG 3.16Å; R146-S149 VanDerWaalsContact O-OG 3.1Å; S149-K151 PolarHBondContact O-N 3.08Å
150	G	63.9	Low	70.1	Confident	44 Å²	44	114.3 Å²	114.3	45%	0.454	58%	0.579	S	S	.	*	S	Bend	trans	-93.7	64.8	177.9	0	0	0	0	0	113	R146 S152	R146-G150 PolarHBondContact O-N 2.96Å; G150-S152 PolarHBondContact O-N 2.93Å
151	K	56.8	Low	68.2	Low	188 Å²	188	117.7 Å²	117.7	82%	0.817	60%	0.595	S	S	*	*			trans	-57.6	90.9	-177.7	-52.5	114.2	172.8	-170.5	0	112.3	S149	S149-K151 PolarHBondContact O-N 3.08Å
152	S	50.4	Low	65.8	Low	97 Å²	97	120.3 Å²	120.3	68%	0.678	61%	0.613	S	S	*	*			trans	-170.5	49.1	148.8	69	0	0	0	0	110.4	G150	G150-S152 PolarHBondContact O-N 2.93Å
153	F	50.8	Low	63.6	Low	186 Å²	186	125.7 Å²	125.7	82%	0.816	64%	0.644	S	S	*	*			trans	-118.1	82.2	158.5	-79.3	-81.3	0	0	0	107.5	P155	F153-P155 VanDerWaalsContact O-CD 3.25Å; F153-P155 WeakPolarHBondContact O-CD 3.19Å
154	Q	47.6	Very low	60.8	Low	149 Å²	149	129.1 Å²	129.1	70%	0.696	66%	0.662	S	S	*	*			trans	-43.2	121	153.8	-70.7	-80.6	32.8	0	0	108.6	L156	Q154-L156 HydrophobicContact CB-CB 4.4Å; Q154-L156 PolarHBondContact O-N 3.33Å
155	P	48.6	Very low	58.2	Low	129 Å²	129	131.1 Å²	131.1	84%	0.838	67%	0.673	S	S	*	*			trans	-91.2	52.7	149.4	36.5	-25.9	0	0	0	107.8	F153	F153-P155 VanDerWaalsContact O-CD 3.25Å; F153-P155 WeakPolarHBondContact O-CD 3.19Å
156	L	47.9	Very low	55.5	Low	137 Å²	137	135.1 Å²	135.1	72%	0.717	70%	0.7	S	S	*	*			trans	-112.6	61.7	171.5	-160.5	76.2	0	0	0	109.4	Q154	Q154-L156 HydrophobicContact CB-CB 4.4Å; Q154-L156 PolarHBondContact O-N 3.33Å
157	S	50.4	Low	52.7	Low	105 Å²	105	132.4 Å²	132.4	73%	0.734	71%	0.709	S	S	*	*			trans	-165.6	64.6	157.7	0.8	0	0	0	0	107.8	P159	S157-P159 WeakPolarHBondContact O-CD 3.41Å
158	R	44.9	Very low	50.5	Low	204 Å²	204	129 Å²	129	77%	0.77	71%	0.713	S	S	*	*			trans	-70.6	117.8	142.5	-174.2	-178	-175.2	-174.3	-0.1	104.2	E160	R158-E160 WeakPolarHBondContact CD-OE1 3.45Å; R158-E160 IonicContact CZ-OE1 3.64Å; R158-E160 IonicContact NE-OE1 3.46Å; R158-E160 IonicContact NH1-OE1 2.8Å; R158-E160 PolarHBondContact O-N 3.25Å
159	P	44.6	Very low	48	Very low	112 Å²	112	126.7 Å²	126.7	73%	0.727	72%	0.72	S	S	*	*			trans	-69.4	93.2	171.7	27.5	-28.9	0	0	0	106.6	S157 I161	S157-P159 WeakPolarHBondContact O-CD 3.41Å; P159-I161 PolarHBondContact O-N 3.5Å; P159-I161 VanDerWaalsContact O-N 3.08Å
160	E	43.1	Very low	46.3	Very low	118 Å²	118	128.8 Å²	128.8	55%	0.551	73%	0.73	S	S	*	*			trans	-62.5	104.7	159.5	-70.6	-74.1	123.9	0	0	105.7	R158 I162	R158-E160 WeakPolarHBondContact CD-OE1 3.45Å; R158-E160 IonicContact CZ-OE1 3.64Å; R158-E160 IonicContact NE-OE1 3.46Å; R158-E160 IonicContact NH1-OE1 2.8Å; R158-E160 PolarHBondContact O-N 3.25Å; E160-I162 HydrophobicContact CB-CD1 4.27Å; E160-I162 HydrophobicContact CB-CG1 4.21Å; E160-I162 PolarHBondContact O-N 2.96Å
161	I	55.9	Low	45.3	Very low	176 Å²	176	134.8 Å²	134.8	90%	0.903	75%	0.746	S	S	*	*			trans	-63.7	80.7	164.2	23.5	170.5	0	0	0	107.7	P159	P159-I161 PolarHBondContact O-N 3.5Å; P159-I161 VanDerWaalsContact O-N 3.08Å
162	I	46.6	Very low	44.6	Very low	120 Å²	120	132.2 Å²	132.2	62%	0.615	75%	0.746	S	S	*	*			trans	-99.5	99.4	165.5	-62.3	173.2	0	0	0	106.6	E160 T164	E160-I162 HydrophobicContact CB-CD1 4.27Å; E160-I162 HydrophobicContact CB-CG1 4.21Å; E160-I162 PolarHBondContact O-N 2.96Å; I162-T164 HydrophobicContact CG2-CG2 3.83Å; I162-T164 PolarHBondContact O-N 3.27Å
163	L	51.1	Low	43.9	Very low	154 Å²	154	137.1 Å²	137.1	81%	0.806	76%	0.755	S	S	*	*			trans	-67.6	98.8	164.4	177.1	69	0	0	0	108.2
164	T	38.7	Very low	43.2	Very low	107 Å²	107	134.5 Å²	134.5	66%	0.656	76%	0.758	S	S	*	*			trans	-125.2	105.3	165.1	42.1	0	0	0	0	110.6	I162	I162-T164 HydrophobicContact CG2-CG2 3.83Å; I162-T164 PolarHBondContact O-N 3.27Å
165	H	39.9	Very low	42.8	Very low	153 Å²	153	135.1 Å²	135.1	71%	0.708	77%	0.766	S	S	*	*			trans	-42.5	127.8	158.6	28.4	-94	0	0	0	113.7
166	S	34.7	Very low	42.6	Very low	112 Å²	112	137.2 Å²	137.2	78%	0.783	76%	0.761	S	S	*	*			trans	32.9	109.9	145.5	-162.9	0	0	0	0	121.8
167	A	36.4	Very low	42	Very low	88 Å²	88	137 Å²	137	73%	0.727	77%	0.768	S	S	*	*				37.5	166	124.7	0	0	0	0	0	122.6
168	P	44.3	Very low	41.3	Very low	131 Å²	131	139.4 Å²	139.4	85%	0.851	77%	0.768	S	S	*	*			cis	-132.6	174.1	-16	31.4	-10.4	0	0	0	114.6
169	G	34.2	Very low	41.1	Very low	66 Å²	66	137.2 Å²	137.2	68%	0.68	77%	0.771	S	S	*	*			trans	104.8	106.9	147.1	0	0	0	0	0	117.7
170	T	41.5	Very low	41.1	Very low	129 Å²	129	137.4 Å²	137.4	79%	0.791	77%	0.772	S	S	*	*				-179.9	134.9	119.5	29.1	0	0	0	0	109.1
171	E	43.3	Very low	41.2	Very low	169 Å²	169	138.8 Å²	138.8	79%	0.79	78%	0.782	S	S	*	*			trans	-47.2	134.3	179.7	53.2	-113.5	68.5	0	0	115.7
172	T	41.2	Very low	40.6	Very low	134 Å²	134	138.3 Å²	138.3	82%	0.822	78%	0.776	S	S	*	*			trans	-156.4	96.1	145.2	16.5	0	0	0	0	109.9	C174	T172-C174 PolarHBondContact O-N 3.46Å
173	K	36.8	Very low	40.3	Very low	200 Å²	200	139.6 Å²	139.6	87%	0.87	79%	0.789	S	S	*	*			trans	-25.7	113.4	151.7	43.5	179.3	176.9	-174.1	0	113.8
174	C	35.9	Very low	39.9	Very low	131 Å²	131	138.8 Å²	138.8	89%	0.885	79%	0.786	S	S	*	*			trans	-143.2	118.4	145.1	-163.5	0	0	0	0	108.6	T172	T172-C174 PolarHBondContact O-N 3.46Å
175	L	39.3	Very low	39.7	Very low	163 Å²	163	139.2 Å²	139.2	85%	0.853	79%	0.788	S	S	*	*			trans	-77.7	141.4	-163.2	-67.3	165.1	0	0	0	111.6
176	K	44.4	Very low	39.5	Very low	172 Å²	172	138.1 Å²	138.1	75%	0.748	79%	0.788	S	S	*	*			trans	-75.5	129.7	174.3	-179.8	153.2	175.4	161.4	0	110.4	Q178	K176-Q178 HydrophobicContact CD-CG 4.4Å; K176-Q178 HydrophobicContact CG-CG 4.17Å
177	P	35.9	Very low	39.5	Very low	132 Å²	132	138.5 Å²	138.5	86%	0.857	79%	0.789	S	S	*	*			trans	-93.3	97	157.3	-3.3	22.9	0	0	0	108.3
178	Q	34.4	Very low	40	Very low	156 Å²	156	140.5 Å²	140.5	73%	0.729	79%	0.786	S	S	*	*			trans	-90.5	133	154.5	-94.8	-106.2	70	0	0	107.2	K176	K176-Q178 HydrophobicContact CD-CG 4.4Å; K176-Q178 HydrophobicContact CG-CG 4.17Å
179	L	40.5	Very low	40.2	Very low	158 Å²	158	140.1 Å²	140.1	83%	0.827	78%	0.784	S	S	*	*			trans	-56	157.2	173.5	-59.4	175.8	0	0	0	112.1
180	P	45.6	Very low	40.5	Very low	116 Å²	116	143.1 Å²	143.1	75%	0.753	78%	0.784	S	S	*	*				-151	137.3	107.7	25.7	-3.5	0	0	0	117.5
181	L	44.4	Very low	41.5	Very low	147 Å²	147	141.5 Å²	141.5	77%	0.77	78%	0.776	S	S	*	*				47.3	125.5	123.1	-65.9	-179.5	0	0	0	123.7
182	E	43	Very low	41.1	Very low	167 Å²	167	141.5 Å²	141.5	78%	0.78	78%	0.782	S	S	*	*			trans	53.3	120.7	139.8	-41.4	-53.4	104.4	0	0	122.7
183	V	41.2	Very low	40.8	Very low	146 Å²	146	138.5 Å²	138.5	89%	0.885	78%	0.777	S	S	*	*				-152.4	125	129.2	65	0	0	0	0	110.8
184	D	41.8	Very low	40.9	Very low	137 Å²	137	133.9 Å²	133.9	73%	0.733	78%	0.777	S	S	*	*			trans	-70.3	158.8	174.7	-172.6	-97.9	0	0	0	111.7
185	V	35.9	Very low	40.8	Very low	116 Å²	116	131.4 Å²	131.4	70%	0.703	77%	0.773	S	S	*	*			trans	163.3	111.8	133.8	163.4	0	0	0	0	110.6
186	N	35.2	Very low	40.7	Very low	131 Å²	131	128 Å²	128	70%	0.701	78%	0.777	S	S	*	*			trans	55.8	134.4	147.9	-74.7	-31.9	0	0	0	119.4
187	C	35.1	Very low	40.5	Very low	120 Å²	120	123.4 Å²	123.4	81%	0.811	78%	0.779	S	S	*	*				-149.7	132.6	53	-67.4	0	0	0	0	112.8
188	L	45.5	Very low	40.9	Very low	129 Å²	129	125.2 Å²	125.2	68%	0.675	78%	0.78	S	S	*	*			trans	-94.3	150.1	138.8	-132.4	95.1	0	0	0	107.9	N190	L188-N190 HydrophobicContact CD2-CB 4.01Å; L188-N190 WeakPolarHBondContact CD2-ND2 3.44Å
189	P	50.3	Low	41.9	Very low	124 Å²	124	123.4 Å²	123.4	81%	0.805	78%	0.784	S	S	*	*				-136.2	142.6	101.3	30.4	-14.8	0	0	0	114.6
190	N	39.8	Very low	42.1	Very low	128 Å²	128	122.7 Å²	122.7	68%	0.684	78%	0.781	S	S	*	*			trans	-65.4	-168	162.3	-104.2	-51.6	0	0	0	111.2	L188	L188-N190 HydrophobicContact CD2-CB 4.01Å; L188-N190 WeakPolarHBondContact CD2-ND2 3.44Å
191	P	61.6	Low	42.5	Very low	95 Å²	95	123 Å²	123	62%	0.617	79%	0.786	S	S	*	*			cis	-136.4	163.2	-43.8	35.3	-19.6	0	0	0	111.8
192	N	35.8	Very low	42.5	Very low	169 Å²	169	120.1 Å²	120.1	90%	0.904	78%	0.778	S	S	*	*			trans	158.3	140.2	134.7	-92.6	-40.9	0	0	0	112.2
193	G	33.5	Very low	43	Very low	71 Å²	71	117.2 Å²	117.2	73%	0.732	78%	0.776	S	S	*	*			trans	136	80.6	151	0	0	0	0	0	116.5
194	A	39.1	Very low	43.4	Very low	104 Å²	104	119.7 Å²	119.7	86%	0.86	78%	0.778	S	S	*	*			trans	53.9	115.7	134.5	0	0	0	0	0	120.6
195	G	35.1	Very low	43.6	Very low	79 Å²	79	116.5 Å²	116.5	81%	0.814	78%	0.778	S	S	*	*				96.4	119.3	105.2	0	0	0	0	0	118.6
196	G	36.8	Very low	44.1	Very low	90 Å²	90	119.3 Å²	119.3	93%	0.928	78%	0.783	S	S	*	*			trans	91.3	125.1	137.5	0	0	0	0	0	117.1
197	G	39.6	Very low	44.4	Very low	76 Å²	76	119.8 Å²	119.8	78%	0.784	79%	0.786	S	S	*	*			trans	154.6	60.1	162.6	0	0	0	0	0	115.5
198	I	44.6	Very low	45	Very low	171 Å²	171	121.1 Å²	121.1	88%	0.877	78%	0.778	S	S	*	*			trans	-67.7	127.8	151.7	42.8	158.9	0	0	0	107.7
199	S	55.8	Low	45.4	Very low	118 Å²	118	122.7 Å²	122.7	83%	0.825	78%	0.782	S	S	*	*			trans	-145.8	116.8	159.9	-75.1	0	0	0	0	109.4
200	D	43.4	Very low	45.4	Very low	142 Å²	142	122 Å²	122	76%	0.759	78%	0.776	S	S	*	*			trans	-56.9	141.3	169	-177	-90.7	0	0	0	111.2	S202	D200-S202 PolarHBondContact OD1-N 3.36Å; D200-S202 VanDerWaalsContact OD1-N 3.1Å
201	S	55.6	Low	45.2	Very low	124 Å²	124	122.1 Å²	122.1	87%	0.867	79%	0.785	S	S	*	*			trans	-136.5	84.2	159.3	-74.6	0	0	0	0	109.2
202	S	44.6	Very low	45.1	Very low	86 Å²	86	121.9 Å²	121.9	60%	0.601	79%	0.786	S	S	*	*			trans	-28.1	131.8	150.6	-171.2	0	0	0	0	116.1	D200	D200-S202 PolarHBondContact OD1-N 3.36Å; D200-S202 VanDerWaalsContact OD1-N 3.1Å
203	S	53.3	Low	46.1	Very low	106 Å²	106	120.3 Å²	120.3	74%	0.741	79%	0.785	S	S	*	*			trans	65.8	107.6	138.6	-54.2	0	0	0	0	120.6
204	Q	48.3	Very low	46.6	Very low	197 Å²	197	124.3 Å²	124.3	92%	0.921	79%	0.788	S	S	*	*				-150.1	122.1	119.9	-153.4	158.7	12.9	0	0	111.2
205	G	46.9	Very low	47	Very low	70 Å²	70	124 Å²	124	72%	0.722	78%	0.78	S	S	*	*			trans	-63.9	144.5	-176.1	0	0	0	0	0	113.2	N207	G205-N207 PolarHBondContact O-N 2.94Å
206	Q	45.4	Very low	47.8	Very low	175 Å²	175	129 Å²	129	82%	0.818	78%	0.782	S	S	*	*			trans	-66.1	106	166.9	-63.9	175.2	-8.1	0	0	108.3	F208	Q206-F208 HydrophobicContact CB-CD2 4.27Å; Q206-F208 PolarHBondContact O-N 3.47Å
207	N	41.9	Very low	48.3	Very low	142 Å²	142	130.2 Å²	130.2	76%	0.759	77%	0.767	S	S	*	*			trans	-86	91.1	157.1	-172.4	-74.3	0	0	0	106.5	G205	G205-N207 PolarHBondContact O-N 2.94Å
208	F	49	Very low	49.1	Very low	148 Å²	148	132.5 Å²	132.5	65%	0.649	77%	0.766	S	S	*	*			trans	-100.9	145.9	157.3	66.4	116.9	0	0	0	105.2	Q206	Q206-F208 HydrophobicContact CB-CD2 4.27Å; Q206-F208 PolarHBondContact O-N 3.47Å
209	E	53.7	Low	49.3	Very low	161 Å²	161	132.1 Å²	132.1	75%	0.752	77%	0.765	S	S	*	*			trans	91.6	68.8	-174.8	-48.9	-178.6	117.4	0	0	115.7
210	T	49.7	Very low	49.1	Very low	111 Å²	111	131.1 Å²	131.1	68%	0.681	76%	0.759	S	S	*	*			trans	-143.5	71.2	132.2	-52.9	0	0	0	0	108.7	S212	T210-S212 PolarHBondContact O-N 3.07Å
211	C	35.8	Very low	49.4	Very low	130 Å²	130	132.6 Å²	132.6	88%	0.878	76%	0.758	S	S	*	*			trans	-85.3	92.3	155.1	-74.5	0	0	0	0	106.5
212	S	58.5	Low	49.5	Very low	90 Å²	90	130.2 Å²	130.2	63%	0.629	74%	0.735	S	S	*	*			trans	-60.7	128.5	163.2	-64.7	0	0	0	0	108.5	T210 L214	T210-S212 PolarHBondContact O-N 3.07Å; S212-L214 VanDerWaalsContact C-N 3.3Å; S212-L214 PolarHBondContact O-N 3.24Å
213	P	56.8	Low	50.4	Low	135 Å²	135	130.1 Å²	130.1	88%	0.877	73%	0.728	S	S	*	*			trans	-78.1	88.1	171.5	31.4	-28.2	0	0	0	107
214	L	44.2	Very low	51.6	Low	155 Å²	155	129.7 Å²	129.7	81%	0.812	73%	0.725	S	S	*	*			trans	-92	109.5	176.5	-174.1	62.2	0	0	0	109.7	S212	S212-L214 VanDerWaalsContact C-N 3.3Å; S212-L214 PolarHBondContact O-N 3.24Å
215	S	48.3	Very low	53	Low	97 Å²	97	123.3 Å²	123.3	68%	0.678	69%	0.693	S	S	*	*			trans	58.2	113.9	156.6	-79.1	0	0	0	0	118.9	D217	S215-D217 VanDerWaalsContact C-N 3.31Å; S215-D217 PolarHBondContact O-N 3.35Å
216	E	52.3	Low	54.6	Low	185 Å²	185	121.8 Å²	121.8	86%	0.864	67%	0.667	S	S	*	*			trans	-50.8	88	150.5	-54.5	164.4	118.2	0	0	110.2
217	D	46.4	Very low	56.2	Low	116 Å²	116	117.8 Å²	117.8	62%	0.62	65%	0.648	S	S	*	*			trans	-105.6	64.5	151.5	-161.8	-96.2	0	0	0	107.2	S215	S215-D217 VanDerWaalsContact C-N 3.31Å; S215-D217 PolarHBondContact O-N 3.35Å
218	V	56.2	Low	58.1	Low	124 Å²	124	117.5 Å²	117.5	75%	0.752	64%	0.642	S	S	*	*			trans	-84	118.9	164.5	-73.5	0	0	0	0	105.7
219	D	48.6	Very low	59.7	Low	162 Å²	162	110.8 Å²	110.8	87%	0.866	61%	0.613	S	S	*	*	S	Bend	trans	102.5	0.4	164	-138.8	-112.6	0	0	0	119.8	K221	D219-K221 PolarHBondContact O-N 3.13Å
220	S	52.5	Low	60.9	Low	98 Å²	98	104.2 Å²	104.2	69%	0.685	58%	0.582	S	S	*	*	S	Bend	trans	-90.9	8.1	-177	-70.9	0	0	0	0	116.5
221	K	49.2	Very low	62.4	Low	173 Å²	173	103.1 Å²	103.1	75%	0.752	58%	0.578	S	S	*	*			trans	-153.5	74.4	-175.1	-151.3	167.5	-173.9	168	0	112.4	D219 D223	D219-K221 PolarHBondContact O-N 3.13Å; K221-D223 PolarHBondContact O-N 2.84Å
222	L	58.3	Low	64.2	Low	73 Å²	73	100.1 Å²	100.1	38%	0.382	56%	0.563	S	S	.	*			trans	-48	120.1	147.1	-121.7	85	0	0	0	105.7	S224 E226 E227	L222-S224 PolarHBondContact O-N 3.45Å; L222-S224 VanDerWaalsContact O-N 3.14Å; L222-E226 WeakPolarHBondContact CA-OE2 3.46Å; L222-E226 HydrophobicContact CD2-CB 4.3Å; L222-E226 VanDerWaalsContact CG-OE2 3.31Å; L222-E226 WeakPolarHBondContact CG-OE2 3.39Å; L222-E227 WeakPolarHBondContact CD2-OE1 3.44Å
223	D	63.9	Low	64.7	Low	84 Å²	84	99.1 Å²	99.1	45%	0.449	55%	0.548	S	S	.	.			trans	-53.2	126	-170.1	-172.4	-98.5	0	0	0	106.4	K221 W225 E226	K221-D223 PolarHBondContact O-N 2.84Å; D223-W225 CarbonylContact O-C 3.56Å; D223-W225 PolarHBondContact O-N 3.19Å; D223-W225 WeakPolarHBondContact OD1-CB 3.5Å; D223-E226 HydrophobicContact CB-CG 4.19Å; D223-E226 PolarHBondContact N-OE2 3.1Å; D223-E226 WeakPolarHBondContact O-CB 3.35Å; D223-E226 PolarHBondContact O-N 3.2Å
224	S	76.9	Confident	65	Low	97 Å²	97	94.6 Å²	94.6	68%	0.678	53%	0.525	S	S	*	.	H	α-helix	trans	-48.7	-22.1	-173.2	171.9	0	0	0	0	113.6	L222 H228	L222-S224 PolarHBondContact O-N 3.45Å; L222-S224 VanDerWaalsContact O-N 3.14Å; S224-H228 PolarHBondContact O-N 3.44Å
225	W	78.9	Confident	65.5	Low	64 Å²	64	94.4 Å²	94.4	24%	0.242	53%	0.525	C	S	.	.	H	α-helix	trans	-74	-31.2	175.2	-166.1	64.2	0	0	0	114.9	L107 R111 D223 H228 I229	L107-W225 HydrophobicContact CD1-CZ2 4.32Å; L107-W225 HydrophobicContact CG-CH2 4.43Å; L107-W225 HydrophobicContact CG-CZ2 4.35Å; L107-W225 WeakPolarHBondContact O-CH2 3.32Å; R111-W225 HydrophobicContact CB-CD2 4.31Å; R111-W225 HydrophobicContact CB-CE3 3.57Å; R111-W225 HydrophobicContact CB-CH2 3.06Å; R111-W225 HydrophobicContact CB-CZ2 3.86Å; R111-W225 HydrophobicContact CB-CZ3 2.9Å; R111-W225 HydrophobicContact CG-CD2 3.76Å; R111-W225 HydrophobicContact CG-CE3 3.24Å; R111-W225 HydrophobicContact CG-CH2 3.64Å; R111-W225 HydrophobicContact CG-CZ2 4.08Å; R111-W225 HydrophobicContact CG-CZ3 3.21Å; D223-W225 CarbonylContact O-C 3.56Å; D223-W225 PolarHBondContact O-N 3.19Å; D223-W225 WeakPolarHBondContact OD1-CB 3.5Å; W225-H228 PolarHBondContact O-N 3.32Å; W225-I229 HydrophobicContact CD2-CD1 3.62Å; W225-I229 HydrophobicContact CD2-CG1 4.32Å; W225-I229 HydrophobicContact CE3-CD1 3.42Å; W225-I229 VanDerWaalsContact CE3-CD1 3.42Å; W225-I229 HydrophobicContact CG-CD1 4.49Å; W225-I229 HydrophobicContact CH2-CD1 3.17Å; W225-I229 HydrophobicContact CH2-CG1 4.34Å; W225-I229 HydrophobicContact CZ2-CD1 3.44Å; W225-I229 VanDerWaalsContact CZ2-CD1 3.44Å; W225-I229 HydrophobicContact CZ2-CG1 4.18Å; W225-I229 HydrophobicContact CZ3-CD1 3.15Å; W225-I229 HydrophobicContact CZ3-CG1 4.5Å; W225-I229 VanDerWaalsContact O-CG1 3.31Å; W225-I229 WeakPolarHBondContact O-CG1 3.34Å; W225-I229 PolarHBondContact O-N 3.36Å
226	E	79.8	Confident	65.5	Low	37 Å²	37	101.7 Å²	101.7	17%	0.173	55%	0.545	C	S	.	.	H	α-helix	trans	-60.9	-48.3	173	-66.4	176.3	126.1	0	0	110.2	L119 L222 D223 H228 I229 F230	L119-E226 HydrophobicContact CD1-CG 4.09Å; L119-E226 WeakPolarHBondContact CD1-OE1 3.43Å; L119-E226 WeakPolarHBondContact CD2-OE1 3.37Å; L222-E226 WeakPolarHBondContact CA-OE2 3.46Å; L222-E226 HydrophobicContact CD2-CB 4.3Å; L222-E226 VanDerWaalsContact CG-OE2 3.31Å; L222-E226 WeakPolarHBondContact CG-OE2 3.39Å; D223-E226 HydrophobicContact CB-CG 4.19Å; D223-E226 PolarHBondContact N-OE2 3.1Å; D223-E226 WeakPolarHBondContact O-CB 3.35Å; D223-E226 PolarHBondContact O-N 3.2Å; E226-H228 VanDerWaalsContact C-N 3.35Å; E226-H228 PolarHBondContact O-N 3.48Å; E226-I229 PolarHBondContact O-N 2.76Å; E226-F230 HydrophobicContact CB-CD2 4.43Å; E226-F230 HydrophobicContact CB-CE2 4.23Å; E226-F230 WeakPolarHBondContact O-CB 3.34Å; E226-F230 WeakPolarHBondContact O-CD2 3.43Å; E226-F230 VanDerWaalsContact O-CG 3.25Å; E226-F230 WeakPolarHBondContact O-CG 3.25Å; E226-F230 PolarHBondContact O-N 3.29Å
227	E	80.2	Confident	66.2	Low	91 Å²	91	97.6 Å²	97.6	43%	0.425	53%	0.529	S	S	.	.	H	α-helix	trans	-62.2	-39.4	176.1	-63.8	-59.5	123.6	0	0	112.2	R122 L222 F230 S231	R122-E227 IonicContact CZ-OE1 3.68Å; R122-E227 IonicContact NH1-OE1 3.76Å; R122-E227 PolarHBondContact NH1-OE1 3.44Å; R122-E227 IonicContact NH2-OE1 3.81Å; L222-E227 WeakPolarHBondContact CD2-OE1 3.44Å; E227-F230 PolarHBondContact O-N 3.02Å; E227-S231 VanDerWaalsContact O-CB 3.26Å; E227-S231 WeakPolarHBondContact O-CB 3.15Å; E227-S231 PolarHBondContact O-N 3.21Å
228	H	80.8	Confident	67.2	Low	137 Å²	137	96.6 Å²	96.6	63%	0.634	53%	0.525	S	S	*	.	H	α-helix	trans	-64.3	-44.5	176.9	-169.8	120.7	0	0	0	112.1	S224 W225 E226 F230 S231 A232	S224-H228 PolarHBondContact O-N 3.44Å; W225-H228 PolarHBondContact O-N 3.32Å; E226-H228 VanDerWaalsContact C-N 3.35Å; E226-H228 PolarHBondContact O-N 3.48Å; H228-F230 VanDerWaalsContact C-N 3.33Å; H228-S231 PolarHBondContact O-N 3.17Å; H228-A232 WeakPolarHBondContact O-CB 3.44Å; H228-A232 PolarHBondContact O-N 2.99Å
229	I	82.6	Confident	67.8	Low	6 Å²	6	95.1 Å²	95.1	3%	0.031	51%	0.512	C	S	.	.	H	α-helix	trans	-63.6	-44.6	178.4	-68.9	166.9	0	0	0	110.4	L104 L107 V108 W225 E226 S231 A232 F233	L104-I229 HydrophobicContact CD1-CG2 3.64Å; L107-I229 HydrophobicContact CD2-CD1 4.33Å; L107-I229 HydrophobicContact CD2-CG1 4.02Å; L107-I229 HydrophobicContact CD2-CG2 4.1Å; L107-I229 HydrophobicContact CG-CD1 4.41Å; V108-I229 HydrophobicContact CG2-CD1 4.3Å; V108-I229 HydrophobicContact CG2-CG2 4.44Å; W225-I229 HydrophobicContact CD2-CD1 3.62Å; W225-I229 HydrophobicContact CD2-CG1 4.32Å; W225-I229 HydrophobicContact CE3-CD1 3.42Å; W225-I229 VanDerWaalsContact CE3-CD1 3.42Å; W225-I229 HydrophobicContact CG-CD1 4.49Å; W225-I229 HydrophobicContact CH2-CD1 3.17Å; W225-I229 HydrophobicContact CH2-CG1 4.34Å; W225-I229 HydrophobicContact CZ2-CD1 3.44Å; W225-I229 VanDerWaalsContact CZ2-CD1 3.44Å; W225-I229 HydrophobicContact CZ2-CG1 4.18Å; W225-I229 HydrophobicContact CZ3-CD1 3.15Å; W225-I229 HydrophobicContact CZ3-CG1 4.5Å; W225-I229 VanDerWaalsContact O-CG1 3.31Å; W225-I229 WeakPolarHBondContact O-CG1 3.34Å; W225-I229 PolarHBondContact O-N 3.36Å; E226-I229 PolarHBondContact O-N 2.76Å; I229-S231 VanDerWaalsContact C-N 3.32Å; I229-S231 PolarHBondContact O-N 3.43Å; I229-A232 PolarHBondContact O-N 3.42Å; I229-F233 HydrophobicContact CG2-CD2 4.29Å; I229-F233 WeakPolarHBondContact O-CD2 3.3Å; I229-F233 PolarHBondContact O-N 3.43Å; I229-F233 VanDerWaalsContact O-N 3.16Å
230	F	79.6	Confident	68.9	Low	23 Å²	23	91.1 Å²	91.1	10%	0.101	49%	0.491	C	S	.	.	H	α-helix	trans	-69.9	-32	-179.6	-62.9	-38.3	0	0	0	112.3	L119 R122 L123 L126 E226 E227 H228 F233 G234	L119-F230 HydrophobicContact CD1-CE2 3.62Å; L119-F230 HydrophobicContact CD1-CZ 3.36Å; R122-F230 HydrophobicContact CB-CE1 4.23Å; R122-F230 HydrophobicContact CB-CE2 3.9Å; R122-F230 HydrophobicContact CB-CZ 3.63Å; R122-F230 HydrophobicContact CG-CE2 4.4Å; L123-F230 HydrophobicContact CD2-CE1 3.94Å; L123-F230 HydrophobicContact CG-CE1 4.25Å; L123-F230 HydrophobicContact CG-CZ 4.38Å; L126-F230 HydrophobicContact CD1-CD1 3.2Å; L126-F230 HydrophobicContact CD1-CE1 3.57Å; L126-F230 HydrophobicContact CD1-CG 4.2Å; E226-F230 HydrophobicContact CB-CD2 4.43Å; E226-F230 HydrophobicContact CB-CE2 4.23Å; E226-F230 WeakPolarHBondContact O-CB 3.34Å; E226-F230 WeakPolarHBondContact O-CD2 3.43Å; E226-F230 VanDerWaalsContact O-CG 3.25Å; E226-F230 WeakPolarHBondContact O-CG 3.25Å; E226-F230 PolarHBondContact O-N 3.29Å; E227-F230 PolarHBondContact O-N 3.02Å; H228-F230 VanDerWaalsContact C-N 3.33Å; F230-F233 PolarHBondContact O-N 3.26Å; F230-G234 VanDerWaalsContact O-CA 3.25Å; F230-G234 WeakPolarHBondContact O-CA 3.15Å; F230-G234 PolarHBondContact O-N 2.93Å
231	S	79.6	Confident	70	Confident	88 Å²	88	90.7 Å²	90.7	62%	0.615	48%	0.479	S	S	*	.	H	α-helix	trans	-67	-35.8	170.3	-176.8	0	0	0	0	112.8	E227 H228 I229 F233	E227-S231 VanDerWaalsContact O-CB 3.26Å; E227-S231 WeakPolarHBondContact O-CB 3.15Å; E227-S231 PolarHBondContact O-N 3.21Å; H228-S231 PolarHBondContact O-N 3.17Å; I229-S231 VanDerWaalsContact C-N 3.32Å; I229-S231 PolarHBondContact O-N 3.43Å; S231-F233 VanDerWaalsContact C-N 3.33Å
232	A	73.8	Confident	71.3	Confident	68 Å²	68	85.2 Å²	85.2	56%	0.562	46%	0.461	S	S	*	.	H	α-helix	trans	-72.7	-24.3	179.3	0	0	0	0	0	113.5	H228 I229	H228-A232 WeakPolarHBondContact O-CB 3.44Å; H228-A232 PolarHBondContact O-N 2.99Å; I229-A232 PolarHBondContact O-N 3.42Å
233	F	69.7	Low	72.3	Confident	68 Å²	68	86.1 Å²	86.1	30%	0.298	47%	0.466	S	S	.	.	H	α-helix	trans	-115.5	-13.6	-175.8	-76.5	-89	0	0	0	114.5	L104 L107 I229 F230 S231 N235	L104-F233 HydrophobicContact CD1-CB 4.41Å; L104-F233 HydrophobicContact CD1-CD1 4.35Å; L104-F233 HydrophobicContact CD1-CD2 3.79Å; L104-F233 HydrophobicContact CD1-CE2 4.09Å; L104-F233 HydrophobicContact CD1-CG 3.93Å; L104-F233 HydrophobicContact CD1-CZ 4.49Å; L107-F233 HydrophobicContact CD2-CE2 3.94Å; I229-F233 HydrophobicContact CG2-CD2 4.29Å; I229-F233 WeakPolarHBondContact O-CD2 3.3Å; I229-F233 PolarHBondContact O-N 3.43Å; I229-F233 VanDerWaalsContact O-N 3.16Å; F230-F233 PolarHBondContact O-N 3.26Å; S231-F233 VanDerWaalsContact C-N 3.33Å; F233-N235 PolarHBondContact O-N 3.1Å
234	G	62.5	Low	72.9	Confident	40 Å²	40	86.2 Å²	86.2	41%	0.412	47%	0.468	S	S	.	.			trans	-92.3	17.5	-172.6	0	0	0	0	0	115.7	F230	F230-G234 VanDerWaalsContact O-CA 3.25Å; F230-G234 WeakPolarHBondContact O-CA 3.15Å; F230-G234 PolarHBondContact O-N 2.93Å
235	N	55.4	Low	72.6	Confident	151 Å²	151	85.3 Å²	85.3	81%	0.807	45%	0.45	S	S	*	.			trans	-102.3	38.5	-176.9	-119	51	0	0	0	113	F233	F233-N235 PolarHBondContact O-N 3.1Å
236	F	48.2	Very low	72	Confident	251 Å²	251	87.3 Å²	87.3	100%	1.101	47%	0.469	S	S	*	.			trans	-120.1	0	176.3	-86.4	-76.6	0	0	0	112

Retrieved 236 of 236 residues in 91.9 ms (Link to these results)

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