G4LUC7_SCHMA Loading...

G-protein coupled receptor, putative

AlphaFold DB , UniProt , Accession G4LUC7, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 478 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	26.4	Very low	32.3	Very low	241 Å²	241	91.5 Å²	91.5	100%	1.187	53%	0.525	S	S	*	.				0	90.6	0	-77.3	173.6	163.8	0	0	106.4
2	N	26	Very low	32	Very low	165 Å²	165	94.7 Å²	94.7	88%	0.882	53%	0.531	S	S	*	.			trans	-85.8	126.5	-179.5	-74.7	2	0	0	0	108	S4	N2-S4 PolarHBondContact O-N 2.79Å
3	A	27	Very low	31.7	Very low	89 Å²	89	98.5 Å²	98.5	74%	0.736	55%	0.549	S	S	*	.			trans	-54.9	129.7	-177.7	0	0	0	0	0	110.4	D5	A3-D5 PolarHBondContact O-N 3.32Å
4	S	26.7	Very low	31.4	Very low	44 Å²	44	101.9 Å²	101.9	31%	0.308	57%	0.566	S	S	.	*			trans	-60	108.1	176.6	28	0	0	0	0	111.6	N2 I6	N2-S4 PolarHBondContact O-N 2.79Å; S4-I6 PolarHBondContact O-N 3.16Å
5	D	27.2	Very low	31	Very low	119 Å²	119	107.8 Å²	107.8	64%	0.636	58%	0.583	S	S	*	*			trans	-70.2	72.5	166.5	-77.6	-33.5	0	0	0	110.6	A3 I7 V190	A3-D5 PolarHBondContact O-N 3.32Å; D5-I7 PolarHBondContact O-N 3.42Å; D5-V190 HydrophobicContact CB-CG2 4.14Å; D5-V190 WeakPolarHBondContact O-CG1 3.31Å
6	I	38.8	Very low	30.8	Very low	16 Å²	16	107.9 Å²	107.9	8%	0.082	60%	0.595	C	S	.	*			trans	-65.2	105.9	179	-59.3	-168.6	0	0	0	109.9	S4 T103 D104 I107 V190 L191	S4-I6 PolarHBondContact O-N 3.16Å; I6-T103 HydrophobicContact CB-CG2 4.03Å; I6-D104 WeakPolarHBondContact CD1-OD1 3.47Å; I6-I107 HydrophobicContact CB-CD1 4.5Å; I6-I107 HydrophobicContact CD1-CD1 3.38Å; I6-I107 HydrophobicContact CG1-CD1 4.43Å; I6-I107 HydrophobicContact CG2-CD1 3.54Å; I6-I107 HydrophobicContact CG2-CG1 3.99Å; I6-V190 VanDerWaalsContact CA-CG1 3.46Å; I6-V190 HydrophobicContact CB-CG1 4.43Å; I6-V190 HydrophobicContact CG1-CG1 4.22Å; I6-L191 WeakPolarHBondContact CB-O 3.32Å; I6-L191 HydrophobicContact CD1-CB 3.85Å; I6-L191 HydrophobicContact CD1-CD2 4.21Å; I6-L191 HydrophobicContact CD1-CG 4.29Å; I6-L191 WeakPolarHBondContact CD1-O 3.17Å; I6-L191 HydrophobicContact CG1-CB 4.29Å; I6-L191 WeakPolarHBondContact CG1-O 3.49Å; I6-L191 WeakPolarHBondContact CG2-O 3.5Å
7	I	39	Very low	30.6	Very low	101 Å²	101	113.9 Å²	113.9	52%	0.518	61%	0.608	S	S	.	*			trans	-86.2	122.4	169	-56.2	174.1	0	0	0	107.7	D5 V9	D5-I7 PolarHBondContact O-N 3.42Å; I7-V9 HydrophobicContact CB-CG2 3.88Å; I7-V9 HydrophobicContact CG2-CG2 3.51Å; I7-V9 PolarHBondContact O-N 3.04Å
8	L	41.5	Very low	30.5	Very low	56 Å²	56	117.8 Å²	117.8	29%	0.293	62%	0.622	S	S	.	*	B	Isolated β-bridge	trans	-65.1	86	158.9	-95.6	159.4	0	0	0	107.9	T10 Y110 L193	L8-T10 PolarHBondContact O-N 3.01Å; L8-T10 VanDerWaalsContact O-N 3.13Å; L8-Y110 HydrophobicContact CD2-CD2 4.35Å; L8-Y110 HydrophobicContact CD2-CE2 4.47Å; L8-Y110 HydrophobicContact CD2-CG 4.4Å; L8-L193 HydrophobicContact CD2-CD2 3.82Å
9	V	34.5	Very low	30.8	Very low	43 Å²	43	117.1 Å²	117.1	26%	0.261	62%	0.623	S	S	.	*			trans	-82.3	89.1	174.5	-175.2	0	0	0	0	108.2	I7 S11	I7-V9 HydrophobicContact CB-CG2 3.88Å; I7-V9 HydrophobicContact CG2-CG2 3.51Å; I7-V9 PolarHBondContact O-N 3.04Å; V9-S11 PolarHBondContact O-N 3.33Å
10	T	37.6	Very low	31.4	Very low	70 Å²	70	117.5 Å²	117.5	43%	0.429	63%	0.625	S	S	.	*			trans	-65.2	115.4	154.4	53	0	0	0	0	106.9	L8 H12	L8-T10 PolarHBondContact O-N 3.01Å; L8-T10 VanDerWaalsContact O-N 3.13Å; T10-H12 PolarHBondContact O-N 2.91Å
11	S	30.3	Very low	32.1	Very low	63 Å²	63	118 Å²	118	44%	0.441	63%	0.634	S	S	.	*			trans	-19.3	92.1	179	167.8	0	0	0	0	114.5	V9	V9-S11 PolarHBondContact O-N 3.33Å
12	H	29.6	Very low	33.1	Very low	129 Å²	129	113 Å²	113	60%	0.597	61%	0.611	S	S	*	*			trans	-88.9	119.7	164.5	-129.1	-72.2	0	0	0	107.1	T10 N14	T10-H12 PolarHBondContact O-N 2.91Å; H12-N14 PolarHBondContact O-N 3.42Å
13	N	28.1	Very low	34.6	Very low	144 Å²	144	108.3 Å²	108.3	77%	0.77	59%	0.591	S	S	*	*			trans	-68.8	112.6	155.5	-85.7	-23.2	0	0	0	106.5	K15	N13-K15 VanDerWaalsContact C-N 3.29Å; N13-K15 PolarHBondContact O-N 3.48Å
14	N	26.4	Very low	35.9	Very low	147 Å²	147	108.6 Å²	108.6	79%	0.786	58%	0.577	S	S	*	*			trans	-61.9	80.6	174.8	-81.3	-19.8	0	0	0	111.2	H12	H12-N14 PolarHBondContact O-N 3.42Å
15	K	26.2	Very low	37.7	Very low	190 Å²	190	112.8 Å²	112.8	83%	0.826	59%	0.589	S	S	*	*			trans	-146.7	126.6	158.6	-68.9	-168.5	179.7	176.7	0	109.2	N13	N13-K15 VanDerWaalsContact C-N 3.29Å; N13-K15 PolarHBondContact O-N 3.48Å
16	S	27.6	Very low	39.6	Very low	110 Å²	110	109.8 Å²	109.8	77%	0.769	58%	0.581	S	S	*	*			trans	94.5	62.8	172.9	73.7	0	0	0	0	118.9	Q18	S16-Q18 PolarHBondContact O-N 3.37Å
17	Y	27.5	Very low	41	Very low	209 Å²	209	110.8 Å²	110.8	82%	0.82	59%	0.59	S	S	*	*			trans	-86.4	82	148.6	-92.6	-85.3	0	0	0	109.2
18	Q	29.5	Very low	42.6	Very low	184 Å²	184	110.2 Å²	110.2	86%	0.86	59%	0.587	S	S	*	*			trans	-168.9	61.5	160.3	-110.3	175.6	19.5	0	0	110.8	S16	S16-Q18 PolarHBondContact O-N 3.37Å
19	T	34.8	Very low	44.5	Very low	105 Å²	105	111.4 Å²	111.4	64%	0.644	59%	0.593	S	S	*	*	S	Bend	trans	-149	104.3	160.9	32.2	0	0	0	0	111.6	S23	T19-S23 PolarHBondContact O-OG 3.33Å
20	N	43.4	Very low	46.8	Very low	124 Å²	124	110.8 Å²	110.8	66%	0.663	59%	0.587	S	S	*	*			trans	64.3	117	151.5	-59.6	-15.6	0	0	0	120.4	L22 S23 H24	N20-L22 PolarHBondContact O-N 2.94Å; N20-L22 VanDerWaalsContact O-N 3.08Å; N20-S23 PolarHBondContact O-N 3.44Å; N20-S23 VanDerWaalsContact O-N 3.12Å; N20-S23 PolarHBondContact O-OG 3.44Å; N20-H24 PolarHBondContact O-N 2.98Å
21	T	46.2	Very low	49	Very low	130 Å²	130	111.2 Å²	111.2	80%	0.798	58%	0.584	S	S	*	*	H	α-helix	trans	-52.2	-29.4	170	50.5	0	0	0	0	114	K25	T21-K25 WeakPolarHBondContact O-CB 3.35Å; T21-K25 PolarHBondContact O-N 3.43Å
22	L	47.8	Very low	51.7	Low	135 Å²	135	114 Å²	114	71%	0.707	59%	0.586	S	S	*	*	H	α-helix	trans	-71	-40.4	178.8	-163.8	72	0	0	0	112.8	N20 H24 K25 A26	N20-L22 PolarHBondContact O-N 2.94Å; N20-L22 VanDerWaalsContact O-N 3.08Å; L22-H24 VanDerWaalsContact C-N 3.35Å; L22-K25 PolarHBondContact O-N 2.98Å; L22-A26 WeakPolarHBondContact O-CB 3.4Å; L22-A26 PolarHBondContact O-N 3.43Å
23	S	56.2	Low	54.5	Low	66 Å²	66	112.3 Å²	112.3	46%	0.462	58%	0.58	S	S	.	*	H	α-helix	trans	-69.6	-37.3	175	59.4	0	0	0	0	110.3	T19 N20 S27	T19-S23 PolarHBondContact O-OG 3.33Å; N20-S23 PolarHBondContact O-N 3.44Å; N20-S23 VanDerWaalsContact O-N 3.12Å; N20-S23 PolarHBondContact O-OG 3.44Å; S23-S27 VanDerWaalsContact O-CB 3.29Å; S23-S27 WeakPolarHBondContact O-CB 3.33Å; S23-S27 PolarHBondContact O-N 3.28Å; S23-S27 PolarHBondContact O-OG 3.32Å
24	H	56	Low	57.4	Low	95 Å²	95	105.9 Å²	105.9	44%	0.44	55%	0.546	S	S	.	.	H	α-helix	trans	-63.3	-45	173.8	-164.3	-50.7	0	0	0	112	N20 L22 S27 I28	N20-H24 PolarHBondContact O-N 2.98Å; L22-H24 VanDerWaalsContact C-N 3.35Å; H24-S27 WeakPolarHBondContact CA-OG 3.37Å; H24-S27 PolarHBondContact O-N 3.47Å; H24-S27 PolarHBondContact O-OG 3.42Å; H24-I28 VanDerWaalsContact CE1-CD1 3.45Å; H24-I28 WeakPolarHBondContact CE1-CD1 3.45Å; H24-I28 WeakPolarHBondContact ND1-CD1 3.34Å; H24-I28 WeakPolarHBondContact O-CG1 3.34Å; H24-I28 PolarHBondContact O-N 3.23Å
25	K	63.8	Low	60.4	Low	132 Å²	132	98.9 Å²	98.9	57%	0.574	51%	0.508	S	S	*	.	H	α-helix	trans	-63.4	-49.5	177.4	-174.6	174.1	179.8	178.2	0	111.8	T21 L22 S27 I28 D29	T21-K25 WeakPolarHBondContact O-CB 3.35Å; T21-K25 PolarHBondContact O-N 3.43Å; L22-K25 PolarHBondContact O-N 2.98Å; K25-S27 PolarHBondContact O-N 3.24Å; K25-I28 PolarHBondContact O-N 3.29Å; K25-I28 VanDerWaalsContact O-N 3.11Å; K25-D29 VanDerWaalsContact O-CG 3.32Å; K25-D29 PolarHBondContact O-N 3.39Å
26	A	67.2	Low	63.5	Low	57 Å²	57	92.5 Å²	92.5	47%	0.471	48%	0.483	S	S	.	.	H	α-helix	trans	-56.5	-34.4	174.3	0	0	0	0	0	111.7	L22 Y30	L22-A26 WeakPolarHBondContact O-CB 3.4Å; L22-A26 PolarHBondContact O-N 3.43Å; A26-Y30 WeakPolarHBondContact O-CD1 3.37Å; A26-Y30 PolarHBondContact O-N 3.49Å
27	S	68.5	Low	66.6	Low	37 Å²	37	87.5 Å²	87.5	26%	0.259	45%	0.448	S	S	.	.	H	α-helix	trans	-69.1	-40.3	177.5	77.2	0	0	0	0	114.1	S23 H24 K25 Y30 Q31	S23-S27 VanDerWaalsContact O-CB 3.29Å; S23-S27 WeakPolarHBondContact O-CB 3.33Å; S23-S27 PolarHBondContact O-N 3.28Å; S23-S27 PolarHBondContact O-OG 3.32Å; H24-S27 WeakPolarHBondContact CA-OG 3.37Å; H24-S27 PolarHBondContact O-N 3.47Å; H24-S27 PolarHBondContact O-OG 3.42Å; K25-S27 PolarHBondContact O-N 3.24Å; S27-Y30 VanDerWaalsContact CA-CD1 3.45Å; S27-Y30 WeakPolarHBondContact O-CD1 3.42Å; S27-Y30 WeakPolarHBondContact O-CE1 3.32Å; S27-Q31 WeakPolarHBondContact O-CG 3.46Å; S27-Q31 PolarHBondContact O-N 3.37Å
28	I	71.9	Confident	69.7	Low	88 Å²	88	77.7 Å²	77.7	45%	0.451	41%	0.409	S	S	.	.	H	α-helix	trans	-64.9	-45.6	174.7	-67.1	164.9	0	0	0	109.8	H24 K25 Y30 Q31 Y32	H24-I28 VanDerWaalsContact CE1-CD1 3.45Å; H24-I28 WeakPolarHBondContact CE1-CD1 3.45Å; H24-I28 WeakPolarHBondContact ND1-CD1 3.34Å; H24-I28 WeakPolarHBondContact O-CG1 3.34Å; H24-I28 PolarHBondContact O-N 3.23Å; K25-I28 PolarHBondContact O-N 3.29Å; K25-I28 VanDerWaalsContact O-N 3.11Å; I28-Y30 PolarHBondContact O-N 3.39Å; I28-Q31 PolarHBondContact O-N 2.97Å; I28-Y32 WeakPolarHBondContact O-CB 3.25Å; I28-Y32 PolarHBondContact O-N 2.84Å
29	D	81.2	Confident	72.7	Confident	81 Å²	81	69.7 Å²	69.7	43%	0.433	37%	0.373	S	S	.	.	H	α-helix	trans	-60.5	-44.3	-175	-68.9	-21	0	0	0	111.7	K25 I33	K25-D29 VanDerWaalsContact O-CG 3.32Å; K25-D29 PolarHBondContact O-N 3.39Å; D29-I33 VanDerWaalsContact O-CG1 3.29Å; D29-I33 WeakPolarHBondContact O-CG1 3.5Å; D29-I33 PolarHBondContact O-N 2.88Å; D29-I33 VanDerWaalsContact O-N 3.12Å
30	Y	83.2	Confident	75.5	Confident	30 Å²	30	70.5 Å²	70.5	12%	0.118	37%	0.368	C	S	.	.	H	α-helix	trans	-70.3	-38.4	178.4	85.9	-103	0	0	0	112.6	A26 S27 I28 Y32 I33 V34 V407	A26-Y30 WeakPolarHBondContact O-CD1 3.37Å; A26-Y30 PolarHBondContact O-N 3.49Å; S27-Y30 VanDerWaalsContact CA-CD1 3.45Å; S27-Y30 WeakPolarHBondContact O-CD1 3.42Å; S27-Y30 WeakPolarHBondContact O-CE1 3.32Å; I28-Y30 PolarHBondContact O-N 3.39Å; Y30-Y32 VanDerWaalsContact C-N 3.27Å; Y30-Y32 PolarHBondContact O-N 3.49Å; Y30-I33 PolarHBondContact O-N 2.96Å; Y30-V34 HydrophobicContact CD2-CG2 4.47Å; Y30-V34 WeakPolarHBondContact O-CB 3.43Å; Y30-V34 VanDerWaalsContact O-CG2 3.28Å; Y30-V34 WeakPolarHBondContact O-CG2 3.43Å; Y30-V34 PolarHBondContact O-N 3.48Å; Y30-V407 HydrophobicContact CD1-CB 4.46Å; Y30-V407 HydrophobicContact CD1-CG1 4.06Å; Y30-V407 HydrophobicContact CD1-CG2 3.66Å; Y30-V407 HydrophobicContact CD2-CG1 4.39Å; Y30-V407 HydrophobicContact CE1-CG2 3.6Å; Y30-V407 HydrophobicContact CG-CG1 3.93Å; Y30-V407 HydrophobicContact CG-CG2 4.28Å
31	Q	83.8	Confident	78	Confident	79 Å²	79	68.8 Å²	68.8	37%	0.369	36%	0.358	S	S	.	.	H	α-helix	trans	-63.1	-39.9	178.9	-74	-177.2	-0.4	0	0	110.8	S27 I28 V34 A35	S27-Q31 WeakPolarHBondContact O-CG 3.46Å; S27-Q31 PolarHBondContact O-N 3.37Å; I28-Q31 PolarHBondContact O-N 2.97Å; Q31-V34 PolarHBondContact O-N 2.72Å; Q31-A35 WeakPolarHBondContact O-CB 3.28Å; Q31-A35 PolarHBondContact O-N 2.94Å
32	Y	86.1	Confident	80.3	Confident	123 Å²	123	62.6 Å²	62.6	48%	0.482	32%	0.32	S	S	.	.	H	α-helix	trans	-62.9	-45.4	175.2	-172.8	-101.4	0	0	0	112.1	I28 Y30 V34 A35 I36 L98	I28-Y32 WeakPolarHBondContact O-CB 3.25Å; I28-Y32 PolarHBondContact O-N 2.84Å; Y30-Y32 VanDerWaalsContact C-N 3.27Å; Y30-Y32 PolarHBondContact O-N 3.49Å; Y32-V34 PolarHBondContact O-N 3.31Å; Y32-A35 PolarHBondContact O-N 3.24Å; Y32-I36 HydrophobicContact CD1-CD1 3.76Å; Y32-I36 HydrophobicContact CE1-CD1 3.24Å; Y32-I36 HydrophobicContact CE1-CG1 4.2Å; Y32-I36 WeakPolarHBondContact O-CG1 3.35Å; Y32-I36 PolarHBondContact O-N 3.46Å; Y32-L98 HydrophobicContact CD2-CD2 3.68Å; Y32-L98 HydrophobicContact CE2-CD2 3.4Å; Y32-L98 VanDerWaalsContact CE2-CD2 3.4Å
33	I	89	Confident	82.6	Confident	92 Å²	92	57.6 Å²	57.6	47%	0.472	30%	0.295	S	S	.	.	H	α-helix	trans	-59.8	-46	175.2	-68.2	165	0	0	0	111.1	D29 Y30 A35 I36 A37	D29-I33 VanDerWaalsContact O-CG1 3.29Å; D29-I33 WeakPolarHBondContact O-CG1 3.5Å; D29-I33 PolarHBondContact O-N 2.88Å; D29-I33 VanDerWaalsContact O-N 3.12Å; Y30-I33 PolarHBondContact O-N 2.96Å; I33-A35 VanDerWaalsContact C-N 3.34Å; I33-A35 PolarHBondContact O-N 3.24Å; I33-I36 PolarHBondContact O-N 2.97Å; I33-A37 PolarHBondContact O-N 3.26Å
34	V	88.9	Confident	84.6	Confident	10 Å²	10	58.3 Å²	58.3	6%	0.061	30%	0.296	C	S	.	.	H	α-helix	trans	-62	-43.5	178.1	170	0	0	0	0	110.7	Y30 Q31 Y32 A37 Y38 F94 L411	Y30-V34 HydrophobicContact CD2-CG2 4.47Å; Y30-V34 WeakPolarHBondContact O-CB 3.43Å; Y30-V34 VanDerWaalsContact O-CG2 3.28Å; Y30-V34 WeakPolarHBondContact O-CG2 3.43Å; Y30-V34 PolarHBondContact O-N 3.48Å; Q31-V34 PolarHBondContact O-N 2.72Å; Y32-V34 PolarHBondContact O-N 3.31Å; V34-A37 PolarHBondContact O-N 3.35Å; V34-Y38 HydrophobicContact CG1-CD2 3.53Å; V34-Y38 HydrophobicContact CG1-CE2 3.46Å; V34-Y38 VanDerWaalsContact CG1-CE2 3.46Å; V34-Y38 VanDerWaalsContact O-CD2 3.22Å; V34-Y38 WeakPolarHBondContact O-CD2 3.37Å; V34-Y38 PolarHBondContact O-N 3.35Å; V34-F94 HydrophobicContact CG1-CE1 4.42Å; V34-L411 HydrophobicContact CG2-CD2 4.06Å
35	A	89.6	Confident	86.6	Confident	0 Å²	0	55.2 Å²	55.2	0%	0	28%	0.283	C	S	.	.	H	α-helix	trans	-61.6	-46.3	177.5	0	0	0	0	0	112	Q31 Y32 I33 A37 Y38 V39 F94 H97 L98	Q31-A35 WeakPolarHBondContact O-CB 3.28Å; Q31-A35 PolarHBondContact O-N 2.94Å; Y32-A35 PolarHBondContact O-N 3.24Å; I33-A35 VanDerWaalsContact C-N 3.34Å; I33-A35 PolarHBondContact O-N 3.24Å; A35-A37 VanDerWaalsContact C-N 3.3Å; A35-A37 PolarHBondContact O-N 2.95Å; A35-Y38 PolarHBondContact O-N 3Å; A35-V39 VanDerWaalsContact O-CB 3.3Å; A35-V39 WeakPolarHBondContact O-CB 3.5Å; A35-V39 WeakPolarHBondContact O-CG2 3.35Å; A35-V39 PolarHBondContact O-N 2.95Å; A35-F94 HydrophobicContact CB-CB 3.91Å; A35-H97 HydrophobicContact CB-CB 3.88Å; A35-L98 HydrophobicContact CB-CD2 3.99Å; A35-L98 HydrophobicContact CB-CG 4.16Å
36	I	91	Very high	88.2	Confident	56 Å²	56	49 Å²	49	29%	0.287	26%	0.256	S	S	.	.	H	α-helix	trans	-57.2	-45.7	175.1	-73.3	175.7	0	0	0	111	Y32 I33 F40 L98	Y32-I36 HydrophobicContact CD1-CD1 3.76Å; Y32-I36 HydrophobicContact CE1-CD1 3.24Å; Y32-I36 HydrophobicContact CE1-CG1 4.2Å; Y32-I36 WeakPolarHBondContact O-CG1 3.35Å; Y32-I36 PolarHBondContact O-N 3.46Å; I33-I36 PolarHBondContact O-N 2.97Å; I36-F40 HydrophobicContact CB-CD2 4.48Å; I36-F40 HydrophobicContact CG2-CD2 4.14Å; I36-F40 WeakPolarHBondContact O-CB 3.26Å; I36-F40 PolarHBondContact O-N 3.29Å; I36-L98 HydrophobicContact CG1-CD2 4.1Å
37	A	92.9	Very high	89.7	Confident	4 Å²	4	48.2 Å²	48.2	3%	0.033	25%	0.247	C	C	.	.	I	π-helix	trans	-63.8	-44	-178.4	0	0	0	0	0	112.2	I33 V34 A35 I41 Q42 M414	I33-A37 PolarHBondContact O-N 3.26Å; V34-A37 PolarHBondContact O-N 3.35Å; A35-A37 VanDerWaalsContact C-N 3.3Å; A35-A37 PolarHBondContact O-N 2.95Å; A37-I41 HydrophobicContact CB-CD1 4.31Å; A37-I41 VanDerWaalsContact O-CB 3.31Å; A37-I41 WeakPolarHBondContact O-CB 3.49Å; A37-I41 PolarHBondContact O-N 3.3Å; A37-Q42 PolarHBondContact O-N 3.04Å; A37-M414 HydrophobicContact CB-CE 4.03Å; A37-M414 HydrophobicContact CB-CG 3.66Å; A37-M414 HydrophobicContact CB-SD 3.4Å; A37-M414 WeakPolarHBondContact CB-SD 3.43Å
38	Y	92.9	Very high	91.1	Very high	3 Å²	3	50.8 Å²	50.8	1%	0.012	26%	0.257	C	S	.	.	I	π-helix	trans	-69.7	-45.9	176.6	-79.5	-68.6	0	0	0	112.4	V34 A35 Q42 T43 G91 F94 M414	V34-Y38 HydrophobicContact CG1-CD2 3.53Å; V34-Y38 HydrophobicContact CG1-CE2 3.46Å; V34-Y38 VanDerWaalsContact CG1-CE2 3.46Å; V34-Y38 VanDerWaalsContact O-CD2 3.22Å; V34-Y38 WeakPolarHBondContact O-CD2 3.37Å; V34-Y38 PolarHBondContact O-N 3.35Å; A35-Y38 PolarHBondContact O-N 3Å; Y38-Q42 WeakPolarHBondContact O-CB 3.4Å; Y38-T43 PolarHBondContact O-OG1 2.88Å; Y38-G91 VanDerWaalsContact O-CA 3.24Å; Y38-G91 WeakPolarHBondContact O-CA 3.49Å; Y38-F94 VanDerWaalsContact CB-CD2 3.42Å; Y38-F94 HydrophobicContact CD1-CD2 4.48Å; Y38-F94 AromaticContact CD1-CE2 3.92Å; Y38-F94 HydrophobicContact CD1-CE2 3.92Å; Y38-F94 HydrophobicContact CD2-CD1 4.34Å; Y38-F94 AromaticContact CD2-CD2 3.89Å; Y38-F94 HydrophobicContact CD2-CD2 3.89Å; Y38-F94 AromaticContact CD2-CE1 3.98Å; Y38-F94 HydrophobicContact CD2-CE1 3.98Å; Y38-F94 AromaticContact CD2-CE2 3.49Å; Y38-F94 HydrophobicContact CD2-CE2 3.49Å; Y38-F94 VanDerWaalsContact CD2-CE2 3.49Å; Y38-F94 HydrophobicContact CD2-CG 4.3Å; Y38-F94 AromaticContact CD2-CZ 3.54Å; Y38-F94 HydrophobicContact CD2-CZ 3.54Å; Y38-F94 HydrophobicContact CE1-CE2 4.44Å; Y38-F94 HydrophobicContact CE2-CE1 4.29Å; Y38-F94 HydrophobicContact CE2-CE2 4.06Å; Y38-F94 AromaticContact CE2-CZ 3.75Å; Y38-F94 HydrophobicContact CE2-CZ 3.75Å; Y38-F94 AromaticContact CG-CD2 3.71Å; Y38-F94 HydrophobicContact CG-CD2 3.71Å; Y38-F94 AromaticContact CG-CE2 3.44Å; Y38-F94 HydrophobicContact CG-CE2 3.44Å; Y38-F94 VanDerWaalsContact CG-CE2 3.44Å; Y38-F94 HydrophobicContact CG-CG 4.46Å; Y38-F94 AromaticContact CG-CZ 4Å; Y38-F94 HydrophobicContact CG-CZ 4Å; Y38-M414 HydrophobicContact CD2-CG 4.47Å; Y38-M414 HydrophobicContact CE2-CB 4.09Å; Y38-M414 HydrophobicContact CE2-CG 4.09Å
39	V	92.4	Very high	92.3	Very high	16 Å²	16	46.6 Å²	46.6	10%	0.097	24%	0.236	C	C	.	.	I	π-helix	trans	-68.3	-49	-175.4	173.7	0	0	0	0	111.5	A35 T43 G91 F94 L95 L98	A35-V39 VanDerWaalsContact O-CB 3.3Å; A35-V39 WeakPolarHBondContact O-CB 3.5Å; A35-V39 WeakPolarHBondContact O-CG2 3.35Å; A35-V39 PolarHBondContact O-N 2.95Å; V39-T43 WeakPolarHBondContact O-CB 3.44Å; V39-T43 PolarHBondContact O-OG1 3.05Å; V39-G91 WeakPolarHBondContact CG2-O 3.5Å; V39-F94 HydrophobicContact CG2-CB 4.07Å; V39-L95 HydrophobicContact CG1-CD2 4.09Å; V39-L95 HydrophobicContact CG2-CD2 4.47Å; V39-L95 HydrophobicContact CG2-CG 4.4Å; V39-L98 HydrophobicContact CB-CD1 4.09Å; V39-L98 HydrophobicContact CG1-CD1 4.15Å; V39-L98 HydrophobicContact CG2-CD1 3.88Å
40	F	94.2	Very high	93.2	Very high	122 Å²	122	46.4 Å²	46.4	54%	0.535	23%	0.231	S	C	.	.	I	π-helix	trans	-100.6	-51.4	-170.9	-62.1	-70.4	0	0	0	113	I36 T44 L98	I36-F40 HydrophobicContact CB-CD2 4.48Å; I36-F40 HydrophobicContact CG2-CD2 4.14Å; I36-F40 WeakPolarHBondContact O-CB 3.26Å; I36-F40 PolarHBondContact O-N 3.29Å; F40-T44 VanDerWaalsContact O-CB 3.27Å; F40-T44 WeakPolarHBondContact O-CB 3.4Å; F40-T44 PolarHBondContact O-N 3.34Å; F40-T44 PolarHBondContact O-OG1 3.38Å; F40-L98 HydrophobicContact CE2-CD1 3.85Å; F40-L98 HydrophobicContact CZ-CD1 4.45Å
41	I	95.1	Very high	93.9	Very high	88 Å²	88	49.9 Å²	49.9	45%	0.451	25%	0.25	S	S	.	.	I	π-helix	trans	-70.7	-55.6	-173.4	-57.7	177.4	0	0	0	109.9	A37 T44 I45	A37-I41 HydrophobicContact CB-CD1 4.31Å; A37-I41 VanDerWaalsContact O-CB 3.31Å; A37-I41 WeakPolarHBondContact O-CB 3.49Å; A37-I41 PolarHBondContact O-N 3.3Å; I41-T44 PolarHBondContact O-N 3.06Å; I41-I45 HydrophobicContact CG2-CD1 3.72Å; I41-I45 WeakPolarHBondContact O-CG1 3.49Å; I41-I45 PolarHBondContact O-N 2.86Å
42	Q	95.5	Very high	94.6	Very high	0 Å²	0	47.1 Å²	47.1	0%	0	24%	0.238	C	C	.	.	I	π-helix	trans	-63.7	-47.5	-176	-172.4	178.7	-62	0	0	111.9	A37 Y38 T44 I45 C46 N418	A37-Q42 PolarHBondContact O-N 3.04Å; Y38-Q42 WeakPolarHBondContact O-CB 3.4Å; Q42-T44 VanDerWaalsContact C-N 3.26Å; Q42-T44 PolarHBondContact O-N 3.24Å; Q42-I45 PolarHBondContact O-N 3.38Å; Q42-C46 WeakPolarHBondContact O-CB 3.31Å; Q42-C46 PolarHBondContact O-N 3.47Å; Q42-C46 PolarHBondContact O-SG 3.17Å; Q42-N418 VanDerWaalsContact CA-OD1 3.24Å; Q42-N418 WeakPolarHBondContact CA-OD1 3.32Å; Q42-N418 VanDerWaalsContact CB-OD1 3.27Å; Q42-N418 WeakPolarHBondContact CB-OD1 3.48Å; Q42-N418 PolarHBondContact N-OD1 3.3Å
43	T	95.9	Very high	95.2	Very high	31 Å²	31	41.3 Å²	41.3	19%	0.19	22%	0.215	C	C	.	.	H	α-helix	trans	-57.6	-41	179.3	-52	0	0	0	0	111.4	Y38 V39 S47 I88	Y38-T43 PolarHBondContact O-OG1 2.88Å; V39-T43 WeakPolarHBondContact O-CB 3.44Å; V39-T43 PolarHBondContact O-OG1 3.05Å; T43-S47 VanDerWaalsContact O-CB 3.26Å; T43-S47 WeakPolarHBondContact O-CB 3.5Å; T43-S47 PolarHBondContact O-N 3.33Å; T43-S47 PolarHBondContact O-OG 3Å; T43-I88 HydrophobicContact CG2-CG2 4.33Å
44	T	96.9	Very high	95.6	Very high	80 Å²	80	40 Å²	40	49%	0.491	21%	0.209	S	C	.	.	H	α-helix	trans	-66.2	-48.1	177.5	-58.9	0	0	0	0	111.6	F40 I41 Q42 C46 S47 I48	F40-T44 VanDerWaalsContact O-CB 3.27Å; F40-T44 WeakPolarHBondContact O-CB 3.4Å; F40-T44 PolarHBondContact O-N 3.34Å; F40-T44 PolarHBondContact O-OG1 3.38Å; I41-T44 PolarHBondContact O-N 3.06Å; Q42-T44 VanDerWaalsContact C-N 3.26Å; Q42-T44 PolarHBondContact O-N 3.24Å; T44-C46 VanDerWaalsContact C-N 3.35Å; T44-C46 PolarHBondContact O-N 2.9Å; T44-S47 PolarHBondContact O-N 3.15Å; T44-I48 HydrophobicContact CG2-CD1 3.79Å; T44-I48 HydrophobicContact CG2-CG1 4.49Å; T44-I48 WeakPolarHBondContact O-CG1 3.3Å; T44-I48 PolarHBondContact O-N 3.27Å
45	I	97.7	Very high	96	Very high	31 Å²	31	42.1 Å²	42.1	16%	0.159	22%	0.219	C	C	.	.	H	α-helix	trans	-59.4	-46.6	178	-68.1	170.1	0	0	0	110.5	I41 Q42 G49 Q421 F422 A425	I41-I45 HydrophobicContact CG2-CD1 3.72Å; I41-I45 WeakPolarHBondContact O-CG1 3.49Å; I41-I45 PolarHBondContact O-N 2.86Å; Q42-I45 PolarHBondContact O-N 3.38Å; I45-G49 WeakPolarHBondContact O-CA 3.46Å; I45-G49 PolarHBondContact O-N 3.22Å; I45-Q421 HydrophobicContact CG2-CB 3.86Å; I45-F422 HydrophobicContact CG2-CB 4.3Å; I45-A425 HydrophobicContact CG2-CB 4.39Å
46	C	98.2	Very high	96.4	Very high	0 Å²	0	42.1 Å²	42.1	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-65.5	-41.8	-179.8	-65.3	0	0	0	0	111.7	Q42 T44 F50 I88	Q42-C46 WeakPolarHBondContact O-CB 3.31Å; Q42-C46 PolarHBondContact O-N 3.47Å; Q42-C46 PolarHBondContact O-SG 3.17Å; T44-C46 VanDerWaalsContact C-N 3.35Å; T44-C46 PolarHBondContact O-N 2.9Å; C46-F50 WeakPolarHBondContact O-CB 3.37Å; C46-F50 PolarHBondContact O-N 2.92Å; C46-I88 HydrophobicContact CB-CG1 3.79Å
47	S	97.9	Very high	96.8	Very high	42 Å²	42	42 Å²	42	29%	0.294	22%	0.217	S	C	.	.	H	α-helix	trans	-65.9	-48.1	-179.8	-59.6	0	0	0	0	112	T43 T44 I51	T43-S47 VanDerWaalsContact O-CB 3.26Å; T43-S47 WeakPolarHBondContact O-CB 3.5Å; T43-S47 PolarHBondContact O-N 3.33Å; T43-S47 PolarHBondContact O-OG 3Å; T44-S47 PolarHBondContact O-N 3.15Å; S47-I51 WeakPolarHBondContact O-CG1 3.32Å; S47-I51 PolarHBondContact O-N 2.82Å
48	I	98.2	Very high	96.9	Very high	91 Å²	91	44.3 Å²	44.3	47%	0.467	23%	0.233	S	C	.	.	H	α-helix	trans	-64.6	-48.4	176.2	-65.6	172.8	0	0	0	109.7	T44 F50 I51 L52	T44-I48 HydrophobicContact CG2-CD1 3.79Å; T44-I48 HydrophobicContact CG2-CG1 4.49Å; T44-I48 WeakPolarHBondContact O-CG1 3.3Å; T44-I48 PolarHBondContact O-N 3.27Å; I48-F50 VanDerWaalsContact C-N 3.3Å; I48-F50 PolarHBondContact O-N 3.4Å; I48-I51 PolarHBondContact O-N 3.32Å; I48-L52 HydrophobicContact CG2-CD1 3.85Å; I48-L52 HydrophobicContact CG2-CG 4.15Å; I48-L52 WeakPolarHBondContact O-CG 3.3Å; I48-L52 PolarHBondContact O-N 3.36Å
49	G	98.4	Very high	97.1	Very high	0 Å²	0	44.2 Å²	44.2	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-61.4	-36.6	-178.9	0	0	0	0	0	113.5	I45 L52 N53 L84 A425	I45-G49 WeakPolarHBondContact O-CA 3.46Å; I45-G49 PolarHBondContact O-N 3.22Å; G49-L52 PolarHBondContact O-N 2.99Å; G49-N53 WeakPolarHBondContact O-CB 3.4Å; G49-N53 PolarHBondContact O-N 2.9Å; G49-N53 PolarHBondContact O-ND2 3.01Å; G49-L84 VanDerWaalsContact C-CD1 3.48Å; G49-A425 VanDerWaalsContact CA-CB 3.42Å
50	F	98.6	Very high	97.3	Very high	77 Å²	77	43.5 Å²	43.5	34%	0.338	23%	0.228	S	C	.	.	H	α-helix	trans	-59.4	-53.7	173.5	174.8	-108.6	0	0	0	110.6	C46 I48 L52 N53 I54 A81 L84 I88	C46-F50 WeakPolarHBondContact O-CB 3.37Å; C46-F50 PolarHBondContact O-N 2.92Å; I48-F50 VanDerWaalsContact C-N 3.3Å; I48-F50 PolarHBondContact O-N 3.4Å; F50-L52 VanDerWaalsContact C-N 3.34Å; F50-L52 PolarHBondContact O-N 3.36Å; F50-N53 PolarHBondContact O-N 3.03Å; F50-I54 HydrophobicContact CD2-CG1 4.38Å; F50-I54 HydrophobicContact CE1-CG1 4.26Å; F50-I54 HydrophobicContact CE2-CD1 4.13Å; F50-I54 HydrophobicContact CE2-CG1 4.05Å; F50-I54 HydrophobicContact CZ-CD1 4.22Å; F50-I54 HydrophobicContact CZ-CG1 3.99Å; F50-I54 WeakPolarHBondContact O-CG1 3.34Å; F50-I54 PolarHBondContact O-N 3.31Å; F50-A81 HydrophobicContact CD2-CB 4.33Å; F50-A81 VanDerWaalsContact CD2-O 3.25Å; F50-A81 WeakPolarHBondContact CD2-O 3.42Å; F50-A81 HydrophobicContact CE2-CB 4.49Å; F50-L84 HydrophobicContact CB-CB 4.39Å; F50-I88 HydrophobicContact CB-CD1 4.19Å; F50-I88 HydrophobicContact CG-CD1 4.36Å
51	I	98.4	Very high	97.4	Very high	102 Å²	102	42.9 Å²	42.9	52%	0.523	23%	0.229	S	C	.	.	H	α-helix	trans	-58.3	-47.2	179	-63.9	166.1	0	0	0	110.6	S47 I48 N53 I54 I55	S47-I51 WeakPolarHBondContact O-CG1 3.32Å; S47-I51 PolarHBondContact O-N 2.82Å; I48-I51 PolarHBondContact O-N 3.32Å; I51-N53 VanDerWaalsContact C-N 3.34Å; I51-N53 PolarHBondContact O-N 3.29Å; I51-I54 PolarHBondContact O-N 3.41Å; I51-I55 HydrophobicContact CG2-CD1 4.19Å; I51-I55 WeakPolarHBondContact O-CG1 3.45Å; I51-I55 PolarHBondContact O-N 2.86Å
52	L	98.5	Very high	97.4	Very high	22 Å²	22	40.6 Å²	40.6	12%	0.115	22%	0.22	C	C	.	.	H	α-helix	trans	-62.3	-38.7	-179.8	-69.1	-175.8	0	0	0	112.7	I48 G49 F50 I55 N56 F428 F429	I48-L52 HydrophobicContact CG2-CD1 3.85Å; I48-L52 HydrophobicContact CG2-CG 4.15Å; I48-L52 WeakPolarHBondContact O-CG 3.3Å; I48-L52 PolarHBondContact O-N 3.36Å; G49-L52 PolarHBondContact O-N 2.99Å; F50-L52 VanDerWaalsContact C-N 3.34Å; F50-L52 PolarHBondContact O-N 3.36Å; L52-I55 HydrophobicContact CD2-CD1 4.44Å; L52-I55 WeakPolarHBondContact O-CB 3.48Å; L52-I55 PolarHBondContact O-N 3.49Å; L52-N56 PolarHBondContact O-N 2.92Å; L52-F428 HydrophobicContact CB-CB 3.8Å; L52-F428 HydrophobicContact CB-CD2 4.46Å; L52-F428 HydrophobicContact CB-CG 4.04Å; L52-F428 HydrophobicContact CD1-CB 4.29Å; L52-F428 HydrophobicContact CD1-CD1 4.18Å; L52-F428 HydrophobicContact CD1-CG 4.41Å; L52-F428 HydrophobicContact CD2-CD1 3.74Å; L52-F428 HydrophobicContact CD2-CD2 4.28Å; L52-F428 HydrophobicContact CD2-CE1 3.95Å; L52-F428 HydrophobicContact CD2-CG 3.93Å; L52-F428 HydrophobicContact CD2-CZ 4.34Å; L52-F428 HydrophobicContact CG-CB 4.43Å; L52-F428 HydrophobicContact CG-CD1 4.37Å; L52-F428 HydrophobicContact CG-CG 4.34Å; L52-F429 HydrophobicContact CD1-CE2 3.72Å; L52-F429 HydrophobicContact CD1-CZ 3.89Å
53	N	98.2	Very high	97	Very high	0 Å²	0	50.1 Å²	50.1	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-75.4	-29.6	177	-82.2	-68.9	0	0	0	113.4	G49 F50 I51 I55 N56 F57 A81 F424 T427	G49-N53 WeakPolarHBondContact O-CB 3.4Å; G49-N53 PolarHBondContact O-N 2.9Å; G49-N53 PolarHBondContact O-ND2 3.01Å; F50-N53 PolarHBondContact O-N 3.03Å; I51-N53 VanDerWaalsContact C-N 3.34Å; I51-N53 PolarHBondContact O-N 3.29Å; N53-I55 VanDerWaalsContact C-N 3.32Å; N53-N56 WeakPolarHBondContact O-CB 3.42Å; N53-N56 PolarHBondContact O-N 3.18Å; N53-N56 PolarHBondContact OD1-ND2 3.21Å; N53-F57 WeakPolarHBondContact O-CB 3.22Å; N53-F57 PolarHBondContact O-N 3.44Å; N53-A81 HydrophobicContact CB-CB 3.76Å; N53-F424 PolarHBondContact ND2-O 3.34Å; N53-T427 PolarHBondContact OD1-OG1 3.45Å; N53-T427 VanDerWaalsContact OD1-OG1 3.14Å
54	I	98.2	Very high	96.7	Very high	64 Å²	64	53.4 Å²	53.4	33%	0.328	27%	0.274	S	S	.	.	H	α-helix	trans	-64.1	-38.9	168.3	-66.9	-62.5	0	0	0	110.9	F50 I51 F57 S58 A81	F50-I54 HydrophobicContact CD2-CG1 4.38Å; F50-I54 HydrophobicContact CE1-CG1 4.26Å; F50-I54 HydrophobicContact CE2-CD1 4.13Å; F50-I54 HydrophobicContact CE2-CG1 4.05Å; F50-I54 HydrophobicContact CZ-CD1 4.22Å; F50-I54 HydrophobicContact CZ-CG1 3.99Å; F50-I54 WeakPolarHBondContact O-CG1 3.34Å; F50-I54 PolarHBondContact O-N 3.31Å; I51-I54 PolarHBondContact O-N 3.41Å; I54-F57 PolarHBondContact O-N 3.38Å; I54-S58 WeakPolarHBondContact O-CB 3.1Å; I54-S58 PolarHBondContact O-N 3.18Å; I54-S58 PolarHBondContact O-OG 3.14Å; I54-A81 HydrophobicContact CD1-CB 3.91Å; I54-A81 HydrophobicContact CG1-CB 4.31Å
55	I	97.6	Very high	96.6	Very high	56 Å²	56	49.9 Å²	49.9	29%	0.287	25%	0.251	S	S	.	.	H	α-helix	trans	-63.2	-46.8	172.5	-64.6	166.2	0	0	0	110.2	I51 L52 N53 F57 S58 V59 F428 L442	I51-I55 HydrophobicContact CG2-CD1 4.19Å; I51-I55 WeakPolarHBondContact O-CG1 3.45Å; I51-I55 PolarHBondContact O-N 2.86Å; L52-I55 HydrophobicContact CD2-CD1 4.44Å; L52-I55 WeakPolarHBondContact O-CB 3.48Å; L52-I55 PolarHBondContact O-N 3.49Å; N53-I55 VanDerWaalsContact C-N 3.32Å; I55-F57 VanDerWaalsContact C-N 3.35Å; I55-F57 PolarHBondContact O-N 2.86Å; I55-S58 PolarHBondContact O-N 2.91Å; I55-V59 HydrophobicContact CG2-CG2 4.36Å; I55-V59 WeakPolarHBondContact O-CG2 3.3Å; I55-V59 PolarHBondContact O-N 3.37Å; I55-F428 HydrophobicContact CB-CE2 4.33Å; I55-F428 HydrophobicContact CG2-CD2 4.3Å; I55-F428 HydrophobicContact CG2-CE2 3.74Å; I55-L442 HydrophobicContact CG2-CD1 3.64Å
56	N	98	Very high	96.3	Very high	0 Å²	0	50.2 Å²	50.2	0%	0	26%	0.257	C	S	.	.	H	α-helix	trans	-53.3	-51.8	175.7	-73.6	-23.4	0	0	0	111.8	L52 N53 S58 V59 F60 S77 T427 F428 Y431 F438	L52-N56 PolarHBondContact O-N 2.92Å; N53-N56 WeakPolarHBondContact O-CB 3.42Å; N53-N56 PolarHBondContact O-N 3.18Å; N53-N56 PolarHBondContact OD1-ND2 3.21Å; N56-S58 VanDerWaalsContact C-N 3.35Å; N56-S58 PolarHBondContact O-N 2.96Å; N56-V59 PolarHBondContact O-N 3.15Å; N56-F60 HydrophobicContact CB-CD2 4.37Å; N56-F60 HydrophobicContact CB-CE2 4.33Å; N56-F60 WeakPolarHBondContact O-CD2 3.38Å; N56-F60 PolarHBondContact O-N 3.25Å; N56-S77 WeakPolarHBondContact CB-OG 3.42Å; N56-T427 PolarHBondContact ND2-OG1 3.01Å; N56-F428 WeakPolarHBondContact ND2-CA 3.11Å; N56-F428 PolarHBondContact ND2-N 3.04Å; N56-F428 WeakPolarHBondContact OD1-CA 3.43Å; N56-F428 WeakPolarHBondContact OD1-CD2 3.4Å; N56-Y431 HydrophobicContact CB-CD2 4.4Å; N56-Y431 WeakPolarHBondContact OD1-CD2 3.3Å; N56-F438 VanDerWaalsContact OD1-CZ 3.3Å; N56-F438 WeakPolarHBondContact OD1-CZ 3.21Å
57	F	98.2	Very high	96	Very high	52 Å²	52	52.4 Å²	52.4	23%	0.228	28%	0.275	C	S	.	.	H	α-helix	trans	-57.2	-47.6	177.8	175	-102.5	0	0	0	111.8	N53 I54 I55 V59 F60 I61 T74 L78	N53-F57 WeakPolarHBondContact O-CB 3.22Å; N53-F57 PolarHBondContact O-N 3.44Å; I54-F57 PolarHBondContact O-N 3.38Å; I55-F57 VanDerWaalsContact C-N 3.35Å; I55-F57 PolarHBondContact O-N 2.86Å; F57-V59 VanDerWaalsContact C-N 3.27Å; F57-V59 PolarHBondContact O-N 3.39Å; F57-F60 PolarHBondContact O-N 3.15Å; F57-I61 HydrophobicContact CE1-CD1 4.21Å; F57-I61 HydrophobicContact CZ-CD1 3.91Å; F57-I61 WeakPolarHBondContact O-CB 3.31Å; F57-I61 PolarHBondContact O-N 2.82Å; F57-T74 HydrophobicContact CD2-CG2 3.77Å; F57-T74 HydrophobicContact CE2-CG2 3.83Å; F57-L78 HydrophobicContact CD2-CB 3.78Å; F57-L78 HydrophobicContact CD2-CD1 4.29Å; F57-L78 HydrophobicContact CD2-CG 4.42Å; F57-L78 HydrophobicContact CE2-CB 4.06Å; F57-L78 HydrophobicContact CE2-CD1 4.29Å; F57-L78 HydrophobicContact CE2-CD2 3.99Å; F57-L78 HydrophobicContact CE2-CG 4.35Å; F57-L78 HydrophobicContact CZ-CD2 4.47Å
58	S	96.3	Very high	95.9	Very high	53 Å²	53	50.8 Å²	50.8	37%	0.371	26%	0.264	S	S	.	.	H	α-helix	trans	-63.2	-31.2	-179.9	-58.7	0	0	0	0	113	I54 I55 N56 I61	I54-S58 WeakPolarHBondContact O-CB 3.1Å; I54-S58 PolarHBondContact O-N 3.18Å; I54-S58 PolarHBondContact O-OG 3.14Å; I55-S58 PolarHBondContact O-N 2.91Å; N56-S58 VanDerWaalsContact C-N 3.35Å; N56-S58 PolarHBondContact O-N 2.96Å; S58-I61 WeakPolarHBondContact O-CG2 3.3Å
59	V	96.9	Very high	95.7	Very high	1 Å²	1	46.5 Å²	46.5	1%	0.006	24%	0.241	C	C	.	.	H	α-helix	trans	-76.1	-48.7	173.7	175.4	0	0	0	0	110.6	I55 N56 F57 I61 C62 F65 F438 T441 L442 I445	I55-V59 HydrophobicContact CG2-CG2 4.36Å; I55-V59 WeakPolarHBondContact O-CG2 3.3Å; I55-V59 PolarHBondContact O-N 3.37Å; N56-V59 PolarHBondContact O-N 3.15Å; F57-V59 VanDerWaalsContact C-N 3.27Å; F57-V59 PolarHBondContact O-N 3.39Å; V59-I61 VanDerWaalsContact C-N 3.35Å; V59-I61 PolarHBondContact O-N 2.76Å; V59-C62 WeakPolarHBondContact O-CB 3.45Å; V59-C62 PolarHBondContact O-N 3.45Å; V59-C62 PolarHBondContact O-SG 3.33Å; V59-F65 HydrophobicContact CG1-CD2 4.43Å; V59-F65 HydrophobicContact CG1-CE2 3.66Å; V59-F65 HydrophobicContact CG1-CZ 4.21Å; V59-F65 VanDerWaalsContact O-CD2 3.25Å; V59-F65 WeakPolarHBondContact O-CD2 3.46Å; V59-F438 HydrophobicContact CB-CD2 3.98Å; V59-F438 HydrophobicContact CB-CE2 3.56Å; V59-F438 HydrophobicContact CB-CZ 4.15Å; V59-F438 HydrophobicContact CG1-CD2 3.37Å; V59-F438 HydrophobicContact CG1-CE2 3.53Å; V59-F438 HydrophobicContact CG1-CG 4.04Å; V59-F438 HydrophobicContact CG1-CZ 4.29Å; V59-F438 HydrophobicContact CG2-CE2 4Å; V59-F438 HydrophobicContact CG2-CZ 4.06Å; V59-T441 HydrophobicContact CG1-CG2 4.05Å; V59-L442 HydrophobicContact CG2-CB 4.12Å; V59-L442 HydrophobicContact CG2-CD1 3.88Å; V59-I445 HydrophobicContact CG2-CD1 4.07Å
60	F	97.2	Very high	95.6	Very high	2 Å²	2	47.7 Å²	47.7	1%	0.009	25%	0.246	C	C	.	.	H	α-helix	trans	-72.1	-22.6	-174.3	-70.1	-54.3	0	0	0	114.6	N56 F57 C62 F65 Y70 M73 T74 Y431 F438	N56-F60 HydrophobicContact CB-CD2 4.37Å; N56-F60 HydrophobicContact CB-CE2 4.33Å; N56-F60 WeakPolarHBondContact O-CD2 3.38Å; N56-F60 PolarHBondContact O-N 3.25Å; F57-F60 PolarHBondContact O-N 3.15Å; F60-C62 PolarHBondContact O-N 2.89Å; F60-F65 HydrophobicContact CD1-CB 4.32Å; F60-F65 AromaticContact CD1-CD1 3.85Å; F60-F65 HydrophobicContact CD1-CD1 3.85Å; F60-F65 HydrophobicContact CD1-CD2 4.22Å; F60-F65 HydrophobicContact CD1-CE1 4.23Å; F60-F65 AromaticContact CD1-CG 3.86Å; F60-F65 HydrophobicContact CD1-CG 3.86Å; F60-F65 HydrophobicContact CE1-CD1 4.15Å; F60-F65 HydrophobicContact CE1-CE1 4.19Å; F60-F65 VanDerWaalsContact O-CB 3.3Å; F60-F65 WeakPolarHBondContact O-CB 3.32Å; F60-Y70 HydrophobicContact CD1-CD1 4.1Å; F60-Y70 AromaticContact CE1-CD1 3.84Å; F60-Y70 HydrophobicContact CE1-CD1 3.84Å; F60-Y70 HydrophobicContact CE1-CE1 4.18Å; F60-M73 HydrophobicContact CD2-CB 4.45Å; F60-M73 HydrophobicContact CE1-CE 4.09Å; F60-M73 HydrophobicContact CE2-CB 4.37Å; F60-M73 HydrophobicContact CE2-CE 4.1Å; F60-M73 HydrophobicContact CZ-CE 3.53Å; F60-T74 HydrophobicContact CB-CG2 4.2Å; F60-T74 VanDerWaalsContact CB-OG1 3.29Å; F60-T74 WeakPolarHBondContact CB-OG1 3.35Å; F60-T74 PolarHBondContact O-OG1 2.86Å; F60-Y431 HydrophobicContact CE2-CD1 4.47Å; F60-Y431 AromaticContact CE2-CD2 3.61Å; F60-Y431 HydrophobicContact CE2-CD2 3.61Å; F60-Y431 AromaticContact CE2-CE2 3.68Å; F60-Y431 HydrophobicContact CE2-CE2 3.68Å; F60-Y431 HydrophobicContact CE2-CG 4.04Å; F60-Y431 HydrophobicContact CZ-CD1 4.01Å; F60-Y431 AromaticContact CZ-CD2 3.87Å; F60-Y431 HydrophobicContact CZ-CD2 3.87Å; F60-Y431 HydrophobicContact CZ-CE1 4.37Å; F60-Y431 HydrophobicContact CZ-CE2 4.18Å; F60-Y431 AromaticContact CZ-CG 3.78Å; F60-Y431 HydrophobicContact CZ-CG 3.78Å; F60-F438 HydrophobicContact CD1-CD2 4.39Å; F60-F438 HydrophobicContact CD2-CE2 4.44Å; F60-F438 AromaticContact CE1-CD2 3.75Å; F60-F438 HydrophobicContact CE1-CD2 3.75Å; F60-F438 HydrophobicContact CE1-CE2 4.33Å; F60-F438 HydrophobicContact CE2-CD2 4.16Å; F60-F438 AromaticContact CE2-CE2 3.95Å; F60-F438 HydrophobicContact CE2-CE2 3.95Å; F60-F438 AromaticContact CZ-CD2 3.6Å; F60-F438 HydrophobicContact CZ-CD2 3.6Å; F60-F438 AromaticContact CZ-CE2 3.87Å; F60-F438 HydrophobicContact CZ-CE2 3.87Å
61	I	95.9	Very high	95.5	Very high	109 Å²	109	45 Å²	45	56%	0.559	24%	0.235	S	C	*	.	T	Hydrogen-bonded Turn	trans	-65.7	-17	173.2	-157.3	169.3	0	0	0	112.7	F57 S58 V59	F57-I61 HydrophobicContact CE1-CD1 4.21Å; F57-I61 HydrophobicContact CZ-CD1 3.91Å; F57-I61 WeakPolarHBondContact O-CB 3.31Å; F57-I61 PolarHBondContact O-N 2.82Å; S58-I61 WeakPolarHBondContact O-CG2 3.3Å; V59-I61 VanDerWaalsContact C-N 3.35Å; V59-I61 PolarHBondContact O-N 2.76Å
62	C	94.1	Very high	95.5	Very high	39 Å²	39	40.2 Å²	40.2	26%	0.264	21%	0.21	S	C	.	.	S	Bend	trans	-63.3	143	179.6	-69.3	0	0	0	0	112	V59 F60 K64 F65 T441	V59-C62 WeakPolarHBondContact O-CB 3.45Å; V59-C62 PolarHBondContact O-N 3.45Å; V59-C62 PolarHBondContact O-SG 3.33Å; F60-C62 PolarHBondContact O-N 2.89Å; C62-K64 PolarHBondContact O-N 3.07Å; C62-F65 HydrophobicContact CB-CD2 4.28Å; C62-F65 PolarHBondContact O-N 3.48Å; C62-T441 HydrophobicContact CB-CG2 4.13Å
63	K	88.1	Confident	95.4	Very high	201 Å²	201	39.1 Å²	39.1	87%	0.874	21%	0.205	S	C	*	.	G	3₁₀ helix	trans	-53.4	-26.4	-177.4	-66.9	-177.5	178.1	178.5	0	114.7	F65 S66	K63-F65 PolarHBondContact O-N 2.95Å; K63-S66 WeakPolarHBondContact O-CB 3.35Å; K63-S66 PolarHBondContact O-OG 3.36Å
64	K	90	Very high	95.4	Very high	100 Å²	100	40 Å²	40	44%	0.435	21%	0.21	S	C	.	.	G	3₁₀ helix	trans	-57.3	-33.2	175.2	-169.5	175.7	-179.3	-175.9	0	111.8	C62 S66 D437 E440	C62-K64 PolarHBondContact O-N 3.07Å; K64-S66 PolarHBondContact O-N 2.84Å; K64-D437 WeakPolarHBondContact CE-OD1 3.4Å; K64-D437 IonicContact NZ-OD1 2.79Å; K64-D437 PolarHBondContact NZ-OD1 3.23Å; K64-E440 IonicContact NZ-OE2 2.67Å; K64-E440 PolarHBondContact NZ-OE2 2.95Å; K64-E440 VanDerWaalsContact NZ-OE2 3.11Å
65	F	93.5	Very high	95.4	Very high	5 Å²	5	38.5 Å²	38.5	2%	0.022	20%	0.204	C	C	.	.	G	3₁₀ helix	trans	-96.5	47.1	-175	-67.4	-67.3	0	0	0	112.9	V59 F60 C62 K63 Y70 D437 F438 T441	V59-F65 HydrophobicContact CG1-CD2 4.43Å; V59-F65 HydrophobicContact CG1-CE2 3.66Å; V59-F65 HydrophobicContact CG1-CZ 4.21Å; V59-F65 VanDerWaalsContact O-CD2 3.25Å; V59-F65 WeakPolarHBondContact O-CD2 3.46Å; F60-F65 HydrophobicContact CD1-CB 4.32Å; F60-F65 AromaticContact CD1-CD1 3.85Å; F60-F65 HydrophobicContact CD1-CD1 3.85Å; F60-F65 HydrophobicContact CD1-CD2 4.22Å; F60-F65 HydrophobicContact CD1-CE1 4.23Å; F60-F65 AromaticContact CD1-CG 3.86Å; F60-F65 HydrophobicContact CD1-CG 3.86Å; F60-F65 HydrophobicContact CE1-CD1 4.15Å; F60-F65 HydrophobicContact CE1-CE1 4.19Å; F60-F65 VanDerWaalsContact O-CB 3.3Å; F60-F65 WeakPolarHBondContact O-CB 3.32Å; C62-F65 HydrophobicContact CB-CD2 4.28Å; C62-F65 PolarHBondContact O-N 3.48Å; K63-F65 PolarHBondContact O-N 2.95Å; F65-Y70 HydrophobicContact CB-CD2 4.4Å; F65-Y70 HydrophobicContact CB-CG 4.1Å; F65-Y70 AromaticContact CD1-CD1 3.66Å; F65-Y70 HydrophobicContact CD1-CD1 3.66Å; F65-Y70 AromaticContact CD1-CD2 3.8Å; F65-Y70 HydrophobicContact CD1-CD2 3.8Å; F65-Y70 AromaticContact CD1-CE1 3.83Å; F65-Y70 HydrophobicContact CD1-CE1 3.83Å; F65-Y70 AromaticContact CD1-CE2 3.96Å; F65-Y70 HydrophobicContact CD1-CE2 3.96Å; F65-Y70 AromaticContact CD1-CG 3.66Å; F65-Y70 HydrophobicContact CD1-CG 3.66Å; F65-Y70 AromaticContact CD1-CZ 3.97Å; F65-Y70 HydrophobicContact CE1-CD1 4.32Å; F65-Y70 HydrophobicContact CE1-CE1 4.08Å; F65-Y70 HydrophobicContact CE1-CE2 4.49Å; F65-Y70 HydrophobicContact CG-CG 4.35Å; F65-Y70 VanDerWaalsContact O-CB 3.31Å; F65-Y70 WeakPolarHBondContact O-CB 3.48Å; F65-D437 HydrophobicContact CE1-CB 3.99Å; F65-D437 HydrophobicContact CZ-CB 4.11Å; F65-F438 HydrophobicContact CZ-CB 4.38Å; F65-T441 HydrophobicContact CE2-CG2 3.97Å; F65-T441 WeakPolarHBondContact CE2-OG1 3.42Å
66	S	91.8	Very high	95.4	Very high	39 Å²	39	36 Å²	36	27%	0.273	19%	0.191	S	C	.	.			trans	-93.4	4.1	-174.5	59.6	0	0	0	0	114.9	K63 K64 R155	K63-S66 WeakPolarHBondContact O-CB 3.35Å; K63-S66 PolarHBondContact O-OG 3.36Å; K64-S66 PolarHBondContact O-N 2.84Å; S66-R155 WeakPolarHBondContact O-CD 3.3Å; S66-R155 WeakPolarHBondContact O-CG 3.38Å; S66-R155 PolarHBondContact O-NE 3.39Å; S66-R155 PolarHBondContact OG-NH2 2.87Å
67	A	92.4	Very high	95.4	Very high	46 Å²	46	36 Å²	36	38%	0.38	19%	0.191	S	C	.	.	S	Bend	trans	-74.6	153.8	174.1	0	0	0	0	0	110.9	A69 Y70 I71	A67-A69 PolarHBondContact O-N 3.41Å; A67-Y70 HydrophobicContact CB-CD2 3.89Å; A67-Y70 PolarHBondContact O-N 2.87Å; A67-I71 WeakPolarHBondContact O-CG1 3.46Å; A67-I71 PolarHBondContact O-N 3Å
68	S	94.8	Very high	95.4	Very high	8 Å²	8	36.2 Å²	36.2	6%	0.056	19%	0.194	C	C	.	.	H	α-helix	trans	-50.1	-52.1	-176.6	179.6	0	0	0	0	113	Y70 I71 L72 T158	S68-Y70 VanDerWaalsContact C-N 3.32Å; S68-Y70 PolarHBondContact O-N 3.22Å; S68-I71 PolarHBondContact O-N 3.46Å; S68-I71 VanDerWaalsContact O-N 3.16Å; S68-L72 PolarHBondContact O-N 3.41Å; S68-L72 VanDerWaalsContact O-N 3.07Å; S68-T158 WeakPolarHBondContact CB-OG1 3.36Å; S68-T158 WeakPolarHBondContact OG-CG2 3.35Å; S68-T158 PolarHBondContact OG-OG1 3.31Å
69	A	94.5	Very high	95.5	Very high	0 Å²	0	33.9 Å²	33.9	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-53.5	-45	176.2	0	0	0	0	0	113.4	A67 I71 L72 M73 L135 L366 L370	A67-A69 PolarHBondContact O-N 3.41Å; A69-I71 PolarHBondContact O-N 2.84Å; A69-L72 WeakPolarHBondContact O-CB 3.44Å; A69-L72 PolarHBondContact O-N 2.7Å; A69-M73 WeakPolarHBondContact O-CG 3.43Å; A69-M73 PolarHBondContact O-N 2.88Å; A69-L135 HydrophobicContact CB-CD2 4.21Å; A69-L135 WeakPolarHBondContact O-CD2 3.25Å; A69-L366 HydrophobicContact CB-CD2 4.35Å; A69-L370 HydrophobicContact CB-CD1 4.1Å
70	Y	95.8	Very high	95.5	Very high	25 Å²	25	34 Å²	34	10%	0.098	18%	0.179	C	C	.	.	H	α-helix	trans	-71	-32	-178.8	-67.6	-55.5	0	0	0	113.1	F60 F65 A67 S68 L72 M73 T74 L366 N435	F60-Y70 HydrophobicContact CD1-CD1 4.1Å; F60-Y70 AromaticContact CE1-CD1 3.84Å; F60-Y70 HydrophobicContact CE1-CD1 3.84Å; F60-Y70 HydrophobicContact CE1-CE1 4.18Å; F65-Y70 HydrophobicContact CB-CD2 4.4Å; F65-Y70 HydrophobicContact CB-CG 4.1Å; F65-Y70 AromaticContact CD1-CD1 3.66Å; F65-Y70 HydrophobicContact CD1-CD1 3.66Å; F65-Y70 AromaticContact CD1-CD2 3.8Å; F65-Y70 HydrophobicContact CD1-CD2 3.8Å; F65-Y70 AromaticContact CD1-CE1 3.83Å; F65-Y70 HydrophobicContact CD1-CE1 3.83Å; F65-Y70 AromaticContact CD1-CE2 3.96Å; F65-Y70 HydrophobicContact CD1-CE2 3.96Å; F65-Y70 AromaticContact CD1-CG 3.66Å; F65-Y70 HydrophobicContact CD1-CG 3.66Å; F65-Y70 AromaticContact CD1-CZ 3.97Å; F65-Y70 HydrophobicContact CE1-CD1 4.32Å; F65-Y70 HydrophobicContact CE1-CE1 4.08Å; F65-Y70 HydrophobicContact CE1-CE2 4.49Å; F65-Y70 HydrophobicContact CG-CG 4.35Å; F65-Y70 VanDerWaalsContact O-CB 3.31Å; F65-Y70 WeakPolarHBondContact O-CB 3.48Å; A67-Y70 HydrophobicContact CB-CD2 3.89Å; A67-Y70 PolarHBondContact O-N 2.87Å; S68-Y70 VanDerWaalsContact C-N 3.32Å; S68-Y70 PolarHBondContact O-N 3.22Å; Y70-L72 VanDerWaalsContact C-N 3.34Å; Y70-M73 HydrophobicContact CD1-SD 3.71Å; Y70-M73 HydrophobicContact CE1-SD 4.13Å; Y70-M73 PolarHBondContact O-N 3.36Å; Y70-T74 PolarHBondContact O-N 3.06Å; Y70-T74 PolarHBondContact O-OG1 3.18Å; Y70-L366 HydrophobicContact CE1-CD1 3.81Å; Y70-L366 HydrophobicContact CE2-CD2 4.44Å; Y70-N435 WeakPolarHBondContact CE1-ND2 3.49Å
71	I	97.3	Very high	95.6	Very high	22 Å²	22	34 Å²	34	11%	0.113	18%	0.179	C	C	.	.	H	α-helix	trans	-63.1	-44	172.7	-62.3	170.5	0	0	0	109.8	A67 S68 A69 T74 V75 R155 T158 R159 I162	A67-I71 WeakPolarHBondContact O-CG1 3.46Å; A67-I71 PolarHBondContact O-N 3Å; S68-I71 PolarHBondContact O-N 3.46Å; S68-I71 VanDerWaalsContact O-N 3.16Å; A69-I71 PolarHBondContact O-N 2.84Å; I71-T74 WeakPolarHBondContact O-CB 3.14Å; I71-T74 PolarHBondContact O-N 3.49Å; I71-V75 PolarHBondContact O-N 2.94Å; I71-R155 HydrophobicContact CD1-CB 4.15Å; I71-R155 HydrophobicContact CD1-CG 4.03Å; I71-T158 HydrophobicContact CB-CG2 4.26Å; I71-T158 HydrophobicContact CG2-CG2 4.22Å; I71-R159 HydrophobicContact CG2-CG 4.36Å; I71-I162 HydrophobicContact CG2-CD1 3.66Å
72	L	97.7	Very high	95.7	Very high	0 Å²	0	32 Å²	32	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-61.5	-46.3	174	-70	167	0	0	0	111.5	S68 A69 Y70 T74 V75 L76 L131 A134 L135 E138 T158 I162	S68-L72 PolarHBondContact O-N 3.41Å; S68-L72 VanDerWaalsContact O-N 3.07Å; A69-L72 WeakPolarHBondContact O-CB 3.44Å; A69-L72 PolarHBondContact O-N 2.7Å; Y70-L72 VanDerWaalsContact C-N 3.34Å; L72-T74 VanDerWaalsContact C-N 3.27Å; L72-T74 PolarHBondContact O-N 3.2Å; L72-V75 PolarHBondContact O-N 2.79Å; L72-L76 WeakPolarHBondContact O-CB 3.43Å; L72-L76 PolarHBondContact O-N 3.35Å; L72-L131 HydrophobicContact CD2-CD2 3.74Å; L72-A134 HydrophobicContact CD1-CB 4.25Å; L72-A134 HydrophobicContact CD2-CB 4.1Å; L72-L135 HydrophobicContact CB-CD1 4.44Å; L72-L135 HydrophobicContact CB-CD2 3.56Å; L72-L135 HydrophobicContact CB-CG 3.8Å; L72-L135 HydrophobicContact CD1-CD2 3.84Å; L72-L135 HydrophobicContact CD1-CG 4.07Å; L72-L135 HydrophobicContact CG-CD2 4.35Å; L72-E138 HydrophobicContact CD1-CB 4.38Å; L72-T158 HydrophobicContact CD1-CG2 4.4Å; L72-T158 HydrophobicContact CD2-CG2 4.08Å; L72-T158 HydrophobicContact CG-CG2 3.81Å; L72-I162 HydrophobicContact CD2-CD1 3.95Å; L72-I162 HydrophobicContact CD2-CG1 3.68Å
73	M	96.5	Very high	95.9	Very high	0 Å²	0	30.1 Å²	30.1	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-61.2	-34.6	176.9	-67.5	169.4	74.4	0	0	112.7	F60 A69 Y70 V75 L76 S77 L135 L369 L370 Y431	F60-M73 HydrophobicContact CD2-CB 4.45Å; F60-M73 HydrophobicContact CE1-CE 4.09Å; F60-M73 HydrophobicContact CE2-CB 4.37Å; F60-M73 HydrophobicContact CE2-CE 4.1Å; F60-M73 HydrophobicContact CZ-CE 3.53Å; A69-M73 WeakPolarHBondContact O-CG 3.43Å; A69-M73 PolarHBondContact O-N 2.88Å; Y70-M73 HydrophobicContact CD1-SD 3.71Å; Y70-M73 HydrophobicContact CE1-SD 4.13Å; Y70-M73 PolarHBondContact O-N 3.36Å; M73-V75 VanDerWaalsContact C-N 3.35Å; M73-V75 PolarHBondContact O-N 3.22Å; M73-L76 PolarHBondContact O-N 3.25Å; M73-S77 PolarHBondContact O-N 3.11Å; M73-S77 PolarHBondContact O-OG 3.2Å; M73-S77 VanDerWaalsContact O-OG 3.08Å; M73-L135 HydrophobicContact CG-CD1 4.14Å; M73-L135 HydrophobicContact CG-CD2 4.02Å; M73-L369 HydrophobicContact CE-CD2 4.13Å; M73-L370 HydrophobicContact CE-CD2 4.41Å; M73-L370 HydrophobicContact CG-CD2 4.13Å; M73-L370 HydrophobicContact SD-CD2 3.88Å; M73-Y431 HydrophobicContact CE-CD1 3.54Å; M73-Y431 HydrophobicContact CE-CE1 2.99Å; M73-Y431 HydrophobicContact CE-CE2 4.4Å; M73-Y431 HydrophobicContact CE-CG 4.47Å; M73-Y431 VanDerWaalsContact CE-CZ 3.49Å
74	T	97.9	Very high	96.4	Very high	17 Å²	17	20.5 Å²	20.5	10%	0.104	11%	0.114	C	C	.	.	H	α-helix	trans	-58.6	-49.9	176.5	-52.8	0	0	0	0	110.2	F57 F60 Y70 I71 L72 S77 L78	F57-T74 HydrophobicContact CD2-CG2 3.77Å; F57-T74 HydrophobicContact CE2-CG2 3.83Å; F60-T74 HydrophobicContact CB-CG2 4.2Å; F60-T74 VanDerWaalsContact CB-OG1 3.29Å; F60-T74 WeakPolarHBondContact CB-OG1 3.35Å; F60-T74 PolarHBondContact O-OG1 2.86Å; Y70-T74 PolarHBondContact O-N 3.06Å; Y70-T74 PolarHBondContact O-OG1 3.18Å; I71-T74 WeakPolarHBondContact O-CB 3.14Å; I71-T74 PolarHBondContact O-N 3.49Å; L72-T74 VanDerWaalsContact C-N 3.27Å; L72-T74 PolarHBondContact O-N 3.2Å; T74-S77 PolarHBondContact O-N 3.48Å; T74-L78 PolarHBondContact O-N 3.04Å; T74-L78 VanDerWaalsContact O-N 3.15Å
75	V	98.3	Very high	96.7	Very high	33 Å²	33	16.7 Å²	16.7	20%	0.2	10%	0.103	C	C	.	.	H	α-helix	trans	-74.5	-31.8	-178.7	-174.2	0	0	0	0	111.4	I71 L72 M73 L78 A79 L131 I162	I71-V75 PolarHBondContact O-N 2.94Å; L72-V75 PolarHBondContact O-N 2.79Å; M73-V75 VanDerWaalsContact C-N 3.35Å; M73-V75 PolarHBondContact O-N 3.22Å; V75-L78 WeakPolarHBondContact O-CB 3.19Å; V75-L78 PolarHBondContact O-N 3.02Å; V75-A79 WeakPolarHBondContact O-CB 3.48Å; V75-A79 PolarHBondContact O-N 3.3Å; V75-L131 HydrophobicContact CB-CD1 3.93Å; V75-L131 HydrophobicContact CG1-CD1 3.78Å; V75-I162 HydrophobicContact CB-CG2 4.29Å; V75-I162 HydrophobicContact CG1-CG2 4.01Å; V75-I162 HydrophobicContact CG2-CD1 4.09Å; V75-I162 HydrophobicContact CG2-CG2 3.95Å
76	L	97.7	Very high	96.9	Very high	3 Å²	3	17.3 Å²	17.3	2%	0.016	11%	0.107	C	C	.	.	H	α-helix	trans	-59.2	-49.8	171.7	-179.8	62.6	0	0	0	111	L72 M73 L78 A79 D80 L131 L135 V373	L72-L76 WeakPolarHBondContact O-CB 3.43Å; L72-L76 PolarHBondContact O-N 3.35Å; M73-L76 PolarHBondContact O-N 3.25Å; L76-L78 VanDerWaalsContact C-N 3.26Å; L76-L78 PolarHBondContact O-N 2.89Å; L76-A79 PolarHBondContact O-N 2.9Å; L76-D80 WeakPolarHBondContact O-CB 3.34Å; L76-D80 VanDerWaalsContact O-CG 3.26Å; L76-D80 PolarHBondContact O-N 3.12Å; L76-L131 HydrophobicContact CB-CD1 4.25Å; L76-L131 HydrophobicContact CD1-CB 4.36Å; L76-L135 HydrophobicContact CD2-CD1 3.77Å; L76-V373 HydrophobicContact CD2-CG1 4.47Å
77	S	98.2	Very high	97.1	Very high	0 Å²	0	16.2 Å²	16.2	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-61.7	-33.3	176.1	-59.9	0	0	0	0	112.9	N56 M73 T74 A81	N56-S77 WeakPolarHBondContact CB-OG 3.42Å; M73-S77 PolarHBondContact O-N 3.11Å; M73-S77 PolarHBondContact O-OG 3.2Å; M73-S77 VanDerWaalsContact O-OG 3.08Å; T74-S77 PolarHBondContact O-N 3.48Å; S77-A81 WeakPolarHBondContact O-CB 3.24Å; S77-A81 PolarHBondContact O-N 3.43Å
78	L	98.3	Very high	97.3	Very high	58 Å²	58	16.1 Å²	16.1	30%	0.304	9%	0.09	S	C	.	.	H	α-helix	trans	-68.4	-45.3	174	-177.5	62	0	0	0	111.9	F57 T74 V75 L76 A81 I82	F57-L78 HydrophobicContact CD2-CB 3.78Å; F57-L78 HydrophobicContact CD2-CD1 4.29Å; F57-L78 HydrophobicContact CD2-CG 4.42Å; F57-L78 HydrophobicContact CE2-CB 4.06Å; F57-L78 HydrophobicContact CE2-CD1 4.29Å; F57-L78 HydrophobicContact CE2-CD2 3.99Å; F57-L78 HydrophobicContact CE2-CG 4.35Å; F57-L78 HydrophobicContact CZ-CD2 4.47Å; T74-L78 PolarHBondContact O-N 3.04Å; T74-L78 VanDerWaalsContact O-N 3.15Å; V75-L78 WeakPolarHBondContact O-CB 3.19Å; V75-L78 PolarHBondContact O-N 3.02Å; L76-L78 VanDerWaalsContact C-N 3.26Å; L76-L78 PolarHBondContact O-N 2.89Å; L78-A81 PolarHBondContact O-N 3.33Å; L78-I82 HydrophobicContact CD1-CD1 4.28Å; L78-I82 HydrophobicContact CD1-CG1 4.49Å; L78-I82 HydrophobicContact CG-CD1 4.08Å; L78-I82 VanDerWaalsContact O-CG1 3.31Å; L78-I82 WeakPolarHBondContact O-CG1 3.44Å; L78-I82 PolarHBondContact O-N 3.25Å
79	A	98.1	Very high	97.3	Very high	4 Å²	4	17.7 Å²	17.7	3%	0.033	10%	0.1	C	C	.	.	H	α-helix	trans	-63.6	-41.8	178.1	0	0	0	0	0	111.5	V75 L76 I82 T83 I127 S128	V75-A79 WeakPolarHBondContact O-CB 3.48Å; V75-A79 PolarHBondContact O-N 3.3Å; L76-A79 PolarHBondContact O-N 2.9Å; A79-I82 PolarHBondContact O-N 2.75Å; A79-T83 WeakPolarHBondContact O-CB 3.22Å; A79-T83 PolarHBondContact O-N 3.04Å; A79-T83 PolarHBondContact O-OG1 2.96Å; A79-I127 HydrophobicContact CB-CB 4.31Å; A79-I127 HydrophobicContact CB-CG2 3.91Å; A79-S128 VanDerWaalsContact CB-OG 3.32Å; A79-S128 WeakPolarHBondContact CB-OG 3.36Å
80	D	98	Very high	97.1	Very high	3 Å²	3	19 Å²	19	2%	0.016	11%	0.106	C	C	.	.	H	α-helix	trans	-64	-42.7	174.7	-66.6	-9	0	0	0	111.2	L76 T83 L84 S128 F424	L76-D80 WeakPolarHBondContact O-CB 3.34Å; L76-D80 VanDerWaalsContact O-CG 3.26Å; L76-D80 PolarHBondContact O-N 3.12Å; D80-T83 PolarHBondContact O-N 3.48Å; D80-L84 WeakPolarHBondContact O-CB 3.33Å; D80-L84 WeakPolarHBondContact O-CD1 3.18Å; D80-L84 VanDerWaalsContact O-CG 3.31Å; D80-L84 WeakPolarHBondContact O-CG 3.34Å; D80-L84 PolarHBondContact O-N 3Å; D80-S128 WeakPolarHBondContact OD1-CB 3.4Å; D80-S128 PolarHBondContact OD1-OG 3.35Å; D80-F424 HydrophobicContact CB-CB 4.43Å
81	A	98.4	Very high	96.8	Very high	1 Å²	1	17.8 Å²	17.8	1%	0.008	10%	0.101	C	C	.	.	H	α-helix	trans	-59.1	-49	173.9	0	0	0	0	0	111.5	F50 N53 I54 S77 L78 T83 L84 G85	F50-A81 HydrophobicContact CD2-CB 4.33Å; F50-A81 VanDerWaalsContact CD2-O 3.25Å; F50-A81 WeakPolarHBondContact CD2-O 3.42Å; F50-A81 HydrophobicContact CE2-CB 4.49Å; N53-A81 HydrophobicContact CB-CB 3.76Å; I54-A81 HydrophobicContact CD1-CB 3.91Å; I54-A81 HydrophobicContact CG1-CB 4.31Å; S77-A81 WeakPolarHBondContact O-CB 3.24Å; S77-A81 PolarHBondContact O-N 3.43Å; L78-A81 PolarHBondContact O-N 3.33Å; A81-T83 VanDerWaalsContact C-N 3.33Å; A81-T83 PolarHBondContact O-N 3.27Å; A81-L84 PolarHBondContact O-N 3.39Å; A81-G85 PolarHBondContact O-N 2.89Å
82	I	98.4	Very high	96.3	Very high	67 Å²	67	18.7 Å²	18.7	34%	0.344	11%	0.109	S	C	.	.	H	α-helix	trans	-61.9	-44.8	179.3	-62.8	163.5	0	0	0	110	L78 A79 L84 G85 V86 V120 T124	L78-I82 HydrophobicContact CD1-CD1 4.28Å; L78-I82 HydrophobicContact CD1-CG1 4.49Å; L78-I82 HydrophobicContact CG-CD1 4.08Å; L78-I82 VanDerWaalsContact O-CG1 3.31Å; L78-I82 WeakPolarHBondContact O-CG1 3.44Å; L78-I82 PolarHBondContact O-N 3.25Å; A79-I82 PolarHBondContact O-N 2.75Å; I82-L84 VanDerWaalsContact C-N 3.34Å; I82-L84 PolarHBondContact O-N 2.88Å; I82-G85 PolarHBondContact O-N 3.06Å; I82-V86 HydrophobicContact CG2-CG1 4.08Å; I82-V86 WeakPolarHBondContact O-CG1 3.49Å; I82-V86 WeakPolarHBondContact O-CG2 3.47Å; I82-V86 PolarHBondContact O-N 2.82Å; I82-V120 HydrophobicContact CG2-CG1 3.96Å; I82-T124 HydrophobicContact CB-CG2 3.94Å; I82-T124 HydrophobicContact CG2-CG2 3.66Å
83	T	97.8	Very high	95.8	Very high	0 Å²	0	19.4 Å²	19.4	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-54.9	-47.3	177.8	-57.3	0	0	0	0	112.1	A79 D80 A81 V86 R87 T124 E125 F424	A79-T83 WeakPolarHBondContact O-CB 3.22Å; A79-T83 PolarHBondContact O-N 3.04Å; A79-T83 PolarHBondContact O-OG1 2.96Å; D80-T83 PolarHBondContact O-N 3.48Å; A81-T83 VanDerWaalsContact C-N 3.33Å; A81-T83 PolarHBondContact O-N 3.27Å; T83-V86 WeakPolarHBondContact O-CG2 3.39Å; T83-R87 WeakPolarHBondContact O-CG 3.33Å; T83-T124 WeakPolarHBondContact OG1-CB 3.47Å; T83-T124 PolarHBondContact OG1-OG1 3.38Å; T83-E125 HydrophobicContact CG2-CG 3.75Å; T83-F424 HydrophobicContact CG2-CD2 4.27Å; T83-F424 HydrophobicContact CG2-CE2 3.87Å
84	L	98.3	Very high	95.4	Very high	0 Å²	0	21 Å²	21	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-70.5	-44.7	178.9	-68.9	164.2	0	0	0	111.3	G49 F50 D80 A81 I82 V86 R87 I88 Q421 F424	G49-L84 VanDerWaalsContact C-CD1 3.48Å; F50-L84 HydrophobicContact CB-CB 4.39Å; D80-L84 WeakPolarHBondContact O-CB 3.33Å; D80-L84 WeakPolarHBondContact O-CD1 3.18Å; D80-L84 VanDerWaalsContact O-CG 3.31Å; D80-L84 WeakPolarHBondContact O-CG 3.34Å; D80-L84 PolarHBondContact O-N 3Å; A81-L84 PolarHBondContact O-N 3.39Å; I82-L84 VanDerWaalsContact C-N 3.34Å; I82-L84 PolarHBondContact O-N 2.88Å; L84-V86 PolarHBondContact O-N 3.04Å; L84-R87 PolarHBondContact O-N 3.49Å; L84-I88 WeakPolarHBondContact O-CG1 3.43Å; L84-I88 PolarHBondContact O-N 2.98Å; L84-Q421 HydrophobicContact CD2-CB 3.9Å; L84-Q421 HydrophobicContact CD2-CG 4.38Å; L84-Q421 VanDerWaalsContact CD2-OE1 3.32Å; L84-F424 HydrophobicContact CD1-CB 3.87Å; L84-F424 HydrophobicContact CD2-CB 4.18Å; L84-F424 HydrophobicContact CD2-CD2 4.48Å; L84-F424 HydrophobicContact CG-CB 4.16Å
85	G	97.9	Very high	94.7	Very high	19 Å²	19	23 Å²	23	20%	0.196	13%	0.129	C	C	.	.	H	α-helix	trans	-61	-45.8	-178.2	0	0	0	0	0	112.7	A81 I82 R87 I88	A81-G85 PolarHBondContact O-N 2.89Å; I82-G85 PolarHBondContact O-N 3.06Å; G85-R87 PolarHBondContact O-N 3.16Å; G85-I88 PolarHBondContact O-N 3.25Å
86	V	97.5	Very high	93.9	Very high	19 Å²	19	22.6 Å²	22.6	12%	0.115	13%	0.128	C	C	.	.	H	α-helix	trans	-66	-24.7	178.9	-61	0	0	0	0	112.7	I82 T83 L84 P89 Y112 E117 V120	I82-V86 HydrophobicContact CG2-CG1 4.08Å; I82-V86 WeakPolarHBondContact O-CG1 3.49Å; I82-V86 WeakPolarHBondContact O-CG2 3.47Å; I82-V86 PolarHBondContact O-N 2.82Å; T83-V86 WeakPolarHBondContact O-CG2 3.39Å; L84-V86 PolarHBondContact O-N 3.04Å; V86-P89 WeakPolarHBondContact O-CD 3.25Å; V86-Y112 VanDerWaalsContact CA-OH 3.29Å; V86-Y112 WeakPolarHBondContact CA-OH 3.32Å; V86-Y112 VanDerWaalsContact O-CE1 3.32Å; V86-Y112 WeakPolarHBondContact O-CE1 3.42Å; V86-Y112 PolarHBondContact O-OH 3.5Å; V86-E117 HydrophobicContact CG2-CG 4.46Å; V86-V120 HydrophobicContact CG1-CB 4.44Å; V86-V120 HydrophobicContact CG1-CG1 3.87Å
87	R	96.1	Very high	93.1	Very high	15 Å²	15	26.8 Å²	26.8	6%	0.057	15%	0.147	C	C	.	.	H	α-helix	trans	-86	-11.5	178.7	-77	-161.6	169.7	100.7	-4	115.4	T83 L84 G85 P89 Q90 E117 S121 E125	T83-R87 WeakPolarHBondContact O-CG 3.33Å; L84-R87 PolarHBondContact O-N 3.49Å; G85-R87 PolarHBondContact O-N 3.16Å; R87-P89 VanDerWaalsContact C-N 3.35Å; R87-Q90 WeakPolarHBondContact O-CB 3.44Å; R87-Q90 PolarHBondContact O-N 3Å; R87-Q90 VanDerWaalsContact O-N 3.07Å; R87-E117 HydrophobicContact CG-CG 4.06Å; R87-E117 IonicContact NE-OE1 3.19Å; R87-S121 PolarHBondContact NH2-OG 3.16Å; R87-E125 IonicContact CZ-OE1 3.51Å; R87-E125 IonicContact NH1-OE1 3.11Å; R87-E125 PolarHBondContact NH1-OE1 3.3Å; R87-E125 IonicContact NH2-OE1 3.56Å; R87-E125 PolarHBondContact NH2-OE1 3.43Å
88	I	96.1	Very high	92.2	Very high	45 Å²	45	29.2 Å²	29.2	23%	0.231	16%	0.159	C	C	.	.	G	3₁₀ helix	trans	-53.3	-46.7	179.9	-67.8	171.4	0	0	0	111.9	T43 C46 F50 L84 G85 Q90	T43-I88 HydrophobicContact CG2-CG2 4.33Å; C46-I88 HydrophobicContact CB-CG1 3.79Å; F50-I88 HydrophobicContact CB-CD1 4.19Å; F50-I88 HydrophobicContact CG-CD1 4.36Å; L84-I88 WeakPolarHBondContact O-CG1 3.43Å; L84-I88 PolarHBondContact O-N 2.98Å; G85-I88 PolarHBondContact O-N 3.25Å; I88-Q90 PolarHBondContact O-N 3.32Å
89	P	94.2	Very high	91.1	Very high	41 Å²	41	30.2 Å²	30.2	27%	0.266	17%	0.165	S	C	.	.	G	3₁₀ helix	trans	-69.5	-18.5	-178.8	-20.4	35	0	0	0	114.2	V86 R87 G91 C92 I109 Y112	V86-P89 WeakPolarHBondContact O-CD 3.25Å; R87-P89 VanDerWaalsContact C-N 3.35Å; P89-G91 PolarHBondContact O-N 2.96Å; P89-G91 VanDerWaalsContact O-N 3.13Å; P89-C92 WeakPolarHBondContact O-CB 3.29Å; P89-C92 PolarHBondContact O-N 2.99Å; P89-I109 HydrophobicContact CB-CG2 4.09Å; P89-I109 WeakPolarHBondContact O-CG2 3.31Å; P89-Y112 HydrophobicContact CB-CD1 4.32Å; P89-Y112 HydrophobicContact CB-CE1 4.13Å; P89-Y112 HydrophobicContact CG-CD1 4.48Å; P89-Y112 HydrophobicContact CG-CE1 3.88Å
90	Q	91.1	Very high	89.8	Confident	27 Å²	27	37.1 Å²	37.1	13%	0.126	20%	0.197	C	C	.	.	G	3₁₀ helix	trans	-56.1	-37.2	-170.5	-169.9	-176.9	21.2	0	0	112.6	R87 I88 C92 I93 E117	R87-Q90 WeakPolarHBondContact O-CB 3.44Å; R87-Q90 PolarHBondContact O-N 3Å; R87-Q90 VanDerWaalsContact O-N 3.07Å; I88-Q90 PolarHBondContact O-N 3.32Å; Q90-C92 PolarHBondContact O-N 3.43Å; Q90-I93 HydrophobicContact CG-CD1 4.27Å; Q90-I93 WeakPolarHBondContact O-CB 3.44Å; Q90-I93 WeakPolarHBondContact O-CG1 3.41Å; Q90-I93 PolarHBondContact O-N 3.01Å; Q90-E117 WeakPolarHBondContact CB-OE2 3.09Å; Q90-E117 WeakPolarHBondContact CG-OE1 3.25Å; Q90-E117 WeakPolarHBondContact CG-OE2 3.24Å; Q90-E117 PolarHBondContact NE2-OE1 3.22Å; Q90-E117 PolarHBondContact OE1-OE1 3.07Å; Q90-E117 VanDerWaalsContact OE1-OE1 3.1Å
91	G	88.2	Confident	88.2	Confident	0 Å²	0	44.8 Å²	44.8	0%	0	23%	0.232	C	C	.	.	G	3₁₀ helix	trans	-57.1	-35.9	179.7	0	0	0	0	0	113.2	Y38 V39 P89 I93 F94	Y38-G91 VanDerWaalsContact O-CA 3.24Å; Y38-G91 WeakPolarHBondContact O-CA 3.49Å; V39-G91 WeakPolarHBondContact CG2-O 3.5Å; P89-G91 PolarHBondContact O-N 2.96Å; P89-G91 VanDerWaalsContact O-N 3.13Å; G91-I93 PolarHBondContact O-N 2.84Å; G91-I93 VanDerWaalsContact O-N 3.17Å; G91-F94 PolarHBondContact O-N 2.85Å; G91-F94 VanDerWaalsContact O-N 3.09Å
92	C	88.1	Confident	86.5	Confident	41 Å²	41	45.9 Å²	45.9	28%	0.277	24%	0.241	S	C	.	.	G	3₁₀ helix	trans	-67.3	-16.7	-176.7	-63.8	0	0	0	0	114.1	P89 Q90 F94 L95 I109	P89-C92 WeakPolarHBondContact O-CB 3.29Å; P89-C92 PolarHBondContact O-N 2.99Å; Q90-C92 PolarHBondContact O-N 3.43Å; C92-F94 PolarHBondContact O-N 3.22Å; C92-L95 HydrophobicContact CB-CD1 3.82Å; C92-L95 WeakPolarHBondContact O-CB 3.41Å; C92-L95 PolarHBondContact O-N 3.45Å; C92-I109 HydrophobicContact CB-CD1 3.31Å; C92-I109 HydrophobicContact CB-CG2 4.32Å
93	I	87.2	Confident	85	Confident	15 Å²	15	43.6 Å²	43.6	8%	0.077	23%	0.23	C	C	.	.	G	3₁₀ helix	trans	-57.8	-31.4	171.9	-62	173.2	0	0	0	110.8	Q90 G91 P96 I109 Y110	Q90-I93 HydrophobicContact CG-CD1 4.27Å; Q90-I93 WeakPolarHBondContact O-CB 3.44Å; Q90-I93 WeakPolarHBondContact O-CG1 3.41Å; Q90-I93 PolarHBondContact O-N 3.01Å; G91-I93 PolarHBondContact O-N 2.84Å; G91-I93 VanDerWaalsContact O-N 3.17Å; I93-P96 VanDerWaalsContact O-CD 3.32Å; I93-P96 WeakPolarHBondContact O-CD 3.46Å; I93-I109 HydrophobicContact CD1-CG2 4.34Å; I93-I109 HydrophobicContact CG1-CB 4.34Å; I93-I109 HydrophobicContact CG1-CG2 3.6Å; I93-Y110 HydrophobicContact CD1-CD2 4.26Å; I93-Y110 HydrophobicContact CG2-CD2 3.84Å
94	F	86.7	Confident	84	Confident	34 Å²	34	47.7 Å²	47.7	15%	0.149	25%	0.252	C	S	.	.	G	3₁₀ helix	trans	-93.8	1	-175.6	-57.2	-89.7	0	0	0	113.5	V34 A35 Y38 V39 G91 C92 P96 H97	V34-F94 HydrophobicContact CG1-CE1 4.42Å; A35-F94 HydrophobicContact CB-CB 3.91Å; Y38-F94 VanDerWaalsContact CB-CD2 3.42Å; Y38-F94 HydrophobicContact CD1-CD2 4.48Å; Y38-F94 AromaticContact CD1-CE2 3.92Å; Y38-F94 HydrophobicContact CD1-CE2 3.92Å; Y38-F94 HydrophobicContact CD2-CD1 4.34Å; Y38-F94 AromaticContact CD2-CD2 3.89Å; Y38-F94 HydrophobicContact CD2-CD2 3.89Å; Y38-F94 AromaticContact CD2-CE1 3.98Å; Y38-F94 HydrophobicContact CD2-CE1 3.98Å; Y38-F94 AromaticContact CD2-CE2 3.49Å; Y38-F94 HydrophobicContact CD2-CE2 3.49Å; Y38-F94 VanDerWaalsContact CD2-CE2 3.49Å; Y38-F94 HydrophobicContact CD2-CG 4.3Å; Y38-F94 AromaticContact CD2-CZ 3.54Å; Y38-F94 HydrophobicContact CD2-CZ 3.54Å; Y38-F94 HydrophobicContact CE1-CE2 4.44Å; Y38-F94 HydrophobicContact CE2-CE1 4.29Å; Y38-F94 HydrophobicContact CE2-CE2 4.06Å; Y38-F94 AromaticContact CE2-CZ 3.75Å; Y38-F94 HydrophobicContact CE2-CZ 3.75Å; Y38-F94 AromaticContact CG-CD2 3.71Å; Y38-F94 HydrophobicContact CG-CD2 3.71Å; Y38-F94 AromaticContact CG-CE2 3.44Å; Y38-F94 HydrophobicContact CG-CE2 3.44Å; Y38-F94 VanDerWaalsContact CG-CE2 3.44Å; Y38-F94 HydrophobicContact CG-CG 4.46Å; Y38-F94 AromaticContact CG-CZ 4Å; Y38-F94 HydrophobicContact CG-CZ 4Å; V39-F94 HydrophobicContact CG2-CB 4.07Å; G91-F94 PolarHBondContact O-N 2.85Å; G91-F94 VanDerWaalsContact O-N 3.09Å; C92-F94 PolarHBondContact O-N 3.22Å; F94-P96 VanDerWaalsContact C-CD 3.45Å; F94-H97 AromaticContact CD1-CD2 3.96Å; F94-H97 WeakPolarHBondContact O-CB 3.46Å; F94-H97 PolarHBondContact O-N 2.98Å; F94-H97 VanDerWaalsContact O-N 3.11Å
95	L	84.7	Confident	83.3	Confident	57 Å²	57	50.5 Å²	50.5	30%	0.298	28%	0.275	S	S	.	.	G	3₁₀ helix	trans	-56.6	-39.1	175.3	-81.5	166.3	0	0	0	113.7	V39 C92 H97 L98 N99 A102	V39-L95 HydrophobicContact CG1-CD2 4.09Å; V39-L95 HydrophobicContact CG2-CD2 4.47Å; V39-L95 HydrophobicContact CG2-CG 4.4Å; C92-L95 HydrophobicContact CB-CD1 3.82Å; C92-L95 WeakPolarHBondContact O-CB 3.41Å; C92-L95 PolarHBondContact O-N 3.45Å; L95-H97 PolarHBondContact O-N 3.42Å; L95-H97 VanDerWaalsContact O-N 3.14Å; L95-L98 CarbonylContact O-C 3.04Å; L95-L98 WeakPolarHBondContact O-CA 3.47Å; L95-L98 PolarHBondContact O-N 2.99Å; L95-N99 PolarHBondContact O-N 2.74Å; L95-A102 HydrophobicContact CB-CB 3.94Å
96	P	81.4	Confident	82.6	Confident	26 Å²	26	49.8 Å²	49.8	17%	0.169	27%	0.268	C	S	.	.	G	3₁₀ helix	trans	-57.8	-26.2	176.1	-27.3	36.8	0	0	0	114.2	I93 F94 L98 N99 A106	I93-P96 VanDerWaalsContact O-CD 3.32Å; I93-P96 WeakPolarHBondContact O-CD 3.46Å; F94-P96 VanDerWaalsContact C-CD 3.45Å; P96-L98 VanDerWaalsContact C-N 3.28Å; P96-L98 PolarHBondContact O-N 3.42Å; P96-N99 WeakPolarHBondContact CA-O 3.49Å; P96-A106 HydrophobicContact CG-CB 3.55Å
97	H	79.8	Confident	81.9	Confident	90 Å²	90	49.2 Å²	49.2	42%	0.417	26%	0.264	S	S	.	.	G	3₁₀ helix	trans	-74.1	-18.1	174.3	-62	-67.5	0	0	0	113.4	A35 F94 L95	A35-H97 HydrophobicContact CB-CB 3.88Å; F94-H97 AromaticContact CD1-CD2 3.96Å; F94-H97 WeakPolarHBondContact O-CB 3.46Å; F94-H97 PolarHBondContact O-N 2.98Å; F94-H97 VanDerWaalsContact O-N 3.11Å; L95-H97 PolarHBondContact O-N 3.42Å; L95-H97 VanDerWaalsContact O-N 3.14Å
98	L	78.9	Confident	81.4	Confident	51 Å²	51	56.6 Å²	56.6	27%	0.267	29%	0.293	S	S	.	.	T	Hydrogen-bonded Turn	trans	-103	-36.2	178	-57.5	-179.8	0	0	0	112	Y32 A35 I36 V39 F40 L95 P96	Y32-L98 HydrophobicContact CD2-CD2 3.68Å; Y32-L98 HydrophobicContact CE2-CD2 3.4Å; Y32-L98 VanDerWaalsContact CE2-CD2 3.4Å; A35-L98 HydrophobicContact CB-CD2 3.99Å; A35-L98 HydrophobicContact CB-CG 4.16Å; I36-L98 HydrophobicContact CG1-CD2 4.1Å; V39-L98 HydrophobicContact CB-CD1 4.09Å; V39-L98 HydrophobicContact CG1-CD1 4.15Å; V39-L98 HydrophobicContact CG2-CD1 3.88Å; F40-L98 HydrophobicContact CE2-CD1 3.85Å; F40-L98 HydrophobicContact CZ-CD1 4.45Å; L95-L98 CarbonylContact O-C 3.04Å; L95-L98 WeakPolarHBondContact O-CA 3.47Å; L95-L98 PolarHBondContact O-N 2.99Å; P96-L98 VanDerWaalsContact C-N 3.28Å; P96-L98 PolarHBondContact O-N 3.42Å
99	N	76.8	Confident	81.2	Confident	80 Å²	80	56 Å²	56	43%	0.428	29%	0.29	S	S	.	.			trans	-140.8	112	-178.2	-176.5	8.3	0	0	0	110.3	L95 P96 H101 A102	L95-N99 PolarHBondContact O-N 2.74Å; P96-N99 WeakPolarHBondContact CA-O 3.49Å; N99-H101 PolarHBondContact O-N 3.07Å; N99-H101 PolarHBondContact OD1-N 3.45Å; N99-A102 PolarHBondContact O-N 3.38Å
100	H	69.7	Low	80.9	Confident	149 Å²	149	56 Å²	56	69%	0.69	29%	0.285	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.6	-21	-177.4	-65.7	83.6	0	0	0	113.7	T103	H100-T103 WeakPolarHBondContact O-CG2 3.38Å
101	H	64.7	Low	80.8	Confident	163 Å²	163	57.6 Å²	57.6	76%	0.755	29%	0.293	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.8	-8	-178.8	-62.5	-66	0	0	0	115.1	N99 T103	N99-H101 PolarHBondContact O-N 3.07Å; N99-H101 PolarHBondContact OD1-N 3.45Å; H101-T103 PolarHBondContact O-N 2.69Å
102	A	62.9	Low	81.1	Confident	25 Å²	25	60.8 Å²	60.8	21%	0.207	31%	0.306	C	S	.	.			trans	-93.4	39.7	-170.6	0	0	0	0	0	114.5	L95 N99	L95-A102 HydrophobicContact CB-CB 3.94Å; N99-A102 PolarHBondContact O-N 3.38Å
103	T	67.6	Low	81.2	Confident	19 Å²	19	59.4 Å²	59.4	12%	0.117	30%	0.297	C	S	.	.	H	α-helix	trans	-84.7	-48.6	-163.8	45.3	0	0	0	0	115.6	I6 H100 H101 A105 A106 I107	I6-T103 HydrophobicContact CB-CG2 4.03Å; H100-T103 WeakPolarHBondContact O-CG2 3.38Å; H101-T103 PolarHBondContact O-N 2.69Å; T103-A105 PolarHBondContact O-N 3.19Å; T103-A106 WeakPolarHBondContact O-CB 3.36Å; T103-A106 PolarHBondContact O-N 3.13Å; T103-A106 VanDerWaalsContact O-N 3.15Å; T103-I107 PolarHBondContact O-N 3.39Å
104	D	76.7	Confident	81.4	Confident	85 Å²	85	59.2 Å²	59.2	46%	0.455	30%	0.296	S	S	.	.	H	α-helix	trans	-63.5	-44.2	-173.7	-70.2	-10.5	0	0	0	112	I6 A106 I107 Y108	I6-D104 WeakPolarHBondContact CD1-OD1 3.47Å; D104-A106 VanDerWaalsContact C-N 3.27Å; D104-A106 PolarHBondContact O-N 3.29Å; D104-I107 WeakPolarHBondContact O-CB 3.21Å; D104-I107 PolarHBondContact O-N 2.91Å; D104-Y108 WeakPolarHBondContact O-CD2 3.07Å; D104-Y108 PolarHBondContact O-N 3.49Å
105	A	82.2	Confident	81.7	Confident	59 Å²	59	61.5 Å²	61.5	49%	0.488	30%	0.304	S	S	.	.	H	α-helix	trans	-61.5	-37.2	176.7	0	0	0	0	0	111.9	T103 I107 Y108 I109	T103-A105 PolarHBondContact O-N 3.19Å; A105-I107 VanDerWaalsContact C-N 3.3Å; A105-I107 PolarHBondContact O-N 3.42Å; A105-Y108 PolarHBondContact O-N 2.9Å; A105-I109 WeakPolarHBondContact O-CG1 3.42Å; A105-I109 PolarHBondContact O-N 3.27Å
106	A	83.9	Confident	82.2	Confident	4 Å²	4	61.6 Å²	61.6	3%	0.033	31%	0.307	C	S	.	.	H	α-helix	trans	-64.1	-34.1	178.5	0	0	0	0	0	112.2	P96 T103 D104 I109 Y110	P96-A106 HydrophobicContact CG-CB 3.55Å; T103-A106 WeakPolarHBondContact O-CB 3.36Å; T103-A106 PolarHBondContact O-N 3.13Å; T103-A106 VanDerWaalsContact O-N 3.15Å; D104-A106 VanDerWaalsContact C-N 3.27Å; D104-A106 PolarHBondContact O-N 3.29Å; A106-I109 PolarHBondContact O-N 2.81Å; A106-Y110 VanDerWaalsContact O-CB 3.26Å; A106-Y110 WeakPolarHBondContact O-CB 3.23Å; A106-Y110 PolarHBondContact O-N 3.45Å
107	I	82.9	Confident	82.9	Confident	7 Å²	7	60.5 Å²	60.5	4%	0.036	30%	0.299	C	S	.	.	H	α-helix	trans	-60.4	-52.6	173.2	-73	164.8	0	0	0	111.1	I6 T103 D104 A105 I109 Y110 M111 L184 L191 L193	I6-I107 HydrophobicContact CB-CD1 4.5Å; I6-I107 HydrophobicContact CD1-CD1 3.38Å; I6-I107 HydrophobicContact CG1-CD1 4.43Å; I6-I107 HydrophobicContact CG2-CD1 3.54Å; I6-I107 HydrophobicContact CG2-CG1 3.99Å; T103-I107 PolarHBondContact O-N 3.39Å; D104-I107 WeakPolarHBondContact O-CB 3.21Å; D104-I107 PolarHBondContact O-N 2.91Å; A105-I107 VanDerWaalsContact C-N 3.3Å; A105-I107 PolarHBondContact O-N 3.42Å; I107-I109 VanDerWaalsContact C-N 3.28Å; I107-I109 PolarHBondContact O-N 3.31Å; I107-Y110 WeakPolarHBondContact O-CB 3.06Å; I107-Y110 PolarHBondContact O-N 2.92Å; I107-Y110 VanDerWaalsContact O-N 3.16Å; I107-M111 HydrophobicContact CG2-SD 4.31Å; I107-M111 WeakPolarHBondContact O-CG 3.49Å; I107-M111 PolarHBondContact O-N 2.91Å; I107-L184 HydrophobicContact CG2-CD2 4.12Å; I107-L191 HydrophobicContact CD1-CD2 4.02Å; I107-L191 HydrophobicContact CD1-CG 4.31Å; I107-L193 HydrophobicContact CB-CD1 4.49Å; I107-L193 HydrophobicContact CG1-CB 4.32Å; I107-L193 HydrophobicContact CG2-CD1 3.73Å
108	Y	86.6	Confident	83.5	Confident	170 Å²	170	58.4 Å²	58.4	67%	0.667	29%	0.293	S	S	*	.	H	α-helix	trans	-62.9	-38.4	-177.7	-68.4	-70	0	0	0	111.8	D104 A105 M111 Y112	D104-Y108 WeakPolarHBondContact O-CD2 3.07Å; D104-Y108 PolarHBondContact O-N 3.49Å; A105-Y108 PolarHBondContact O-N 2.9Å; Y108-M111 PolarHBondContact O-N 2.91Å; Y108-Y112 WeakPolarHBondContact O-CB 3.34Å; Y108-Y112 PolarHBondContact O-N 3.06Å
109	I	90.4	Very high	84.2	Confident	34 Å²	34	56 Å²	56	17%	0.174	28%	0.28	C	S	.	.	H	α-helix	trans	-68.8	-37.6	176.8	-64.1	172	0	0	0	110.8	P89 C92 I93 A105 A106 I107 Y112 S113	P89-I109 HydrophobicContact CB-CG2 4.09Å; P89-I109 WeakPolarHBondContact O-CG2 3.31Å; C92-I109 HydrophobicContact CB-CD1 3.31Å; C92-I109 HydrophobicContact CB-CG2 4.32Å; I93-I109 HydrophobicContact CD1-CG2 4.34Å; I93-I109 HydrophobicContact CG1-CB 4.34Å; I93-I109 HydrophobicContact CG1-CG2 3.6Å; A105-I109 WeakPolarHBondContact O-CG1 3.42Å; A105-I109 PolarHBondContact O-N 3.27Å; A106-I109 PolarHBondContact O-N 2.81Å; I107-I109 VanDerWaalsContact C-N 3.28Å; I107-I109 PolarHBondContact O-N 3.31Å; I109-Y112 WeakPolarHBondContact O-CB 3.5Å; I109-Y112 PolarHBondContact O-N 3.5Å; I109-S113 WeakPolarHBondContact O-CB 3.29Å; I109-S113 PolarHBondContact O-N 3.19Å
110	Y	88.2	Confident	85.2	Confident	41 Å²	41	53.9 Å²	53.9	16%	0.161	27%	0.27	C	S	.	.	H	α-helix	trans	-63.9	-43	173.7	-171.7	-94.1	0	0	0	111.8	L8 I93 A106 I107 Y112 S113 I114 L193	L8-Y110 HydrophobicContact CD2-CD2 4.35Å; L8-Y110 HydrophobicContact CD2-CE2 4.47Å; L8-Y110 HydrophobicContact CD2-CG 4.4Å; I93-Y110 HydrophobicContact CD1-CD2 4.26Å; I93-Y110 HydrophobicContact CG2-CD2 3.84Å; A106-Y110 VanDerWaalsContact O-CB 3.26Å; A106-Y110 WeakPolarHBondContact O-CB 3.23Å; A106-Y110 PolarHBondContact O-N 3.45Å; I107-Y110 WeakPolarHBondContact O-CB 3.06Å; I107-Y110 PolarHBondContact O-N 2.92Å; I107-Y110 VanDerWaalsContact O-N 3.16Å; Y110-Y112 PolarHBondContact O-N 3.27Å; Y110-S113 WeakPolarHBondContact O-CB 3.39Å; Y110-S113 PolarHBondContact O-N 2.91Å; Y110-S113 VanDerWaalsContact O-N 3.13Å; Y110-I114 HydrophobicContact CD1-CD1 3.81Å; Y110-I114 HydrophobicContact CD1-CG1 4.43Å; Y110-I114 HydrophobicContact CE1-CD1 3.23Å; Y110-I114 HydrophobicContact CE1-CG1 4.12Å; Y110-I114 PolarHBondContact O-N 3.21Å; Y110-I114 VanDerWaalsContact O-N 3.08Å; Y110-L193 HydrophobicContact CD1-CD1 3.97Å; Y110-L193 HydrophobicContact CD1-CD2 3.35Å; Y110-L193 HydrophobicContact CD1-CG 4.34Å; Y110-L193 HydrophobicContact CE1-CD2 3.37Å; Y110-L193 HydrophobicContact CG-CD2 4.31Å
111	M	90	Very high	86.4	Confident	59 Å²	59	46.9 Å²	46.9	29%	0.291	24%	0.238	S	C	.	.	H	α-helix	trans	-60.4	-45	173.1	-69.8	-177	70.7	0	0	112	I107 Y108 S113 I114 Y115 V182 L193	I107-M111 HydrophobicContact CG2-SD 4.31Å; I107-M111 WeakPolarHBondContact O-CG 3.49Å; I107-M111 PolarHBondContact O-N 2.91Å; Y108-M111 PolarHBondContact O-N 2.91Å; M111-S113 VanDerWaalsContact C-N 3.28Å; M111-S113 PolarHBondContact O-N 3.34Å; M111-I114 PolarHBondContact O-N 2.98Å; M111-Y115 VanDerWaalsContact O-CD2 3.27Å; M111-Y115 WeakPolarHBondContact O-CD2 3.47Å; M111-Y115 PolarHBondContact O-N 2.97Å; M111-V182 HydrophobicContact CG-CG1 4.12Å; M111-L193 HydrophobicContact CG-CD1 4Å
112	Y	93.2	Very high	87.8	Confident	68 Å²	68	39.6 Å²	39.6	27%	0.267	20%	0.204	S	C	.	.	H	α-helix	trans	-57.7	-41.7	172.5	165.4	-90.2	0	0	0	111.6	V86 P89 Y108 I109 Y110 I114 Y115 V116 E117	V86-Y112 VanDerWaalsContact CA-OH 3.29Å; V86-Y112 WeakPolarHBondContact CA-OH 3.32Å; V86-Y112 VanDerWaalsContact O-CE1 3.32Å; V86-Y112 WeakPolarHBondContact O-CE1 3.42Å; V86-Y112 PolarHBondContact O-OH 3.5Å; P89-Y112 HydrophobicContact CB-CD1 4.32Å; P89-Y112 HydrophobicContact CB-CE1 4.13Å; P89-Y112 HydrophobicContact CG-CD1 4.48Å; P89-Y112 HydrophobicContact CG-CE1 3.88Å; Y108-Y112 WeakPolarHBondContact O-CB 3.34Å; Y108-Y112 PolarHBondContact O-N 3.06Å; I109-Y112 WeakPolarHBondContact O-CB 3.5Å; I109-Y112 PolarHBondContact O-N 3.5Å; Y110-Y112 PolarHBondContact O-N 3.27Å; Y112-I114 VanDerWaalsContact C-N 3.32Å; Y112-I114 PolarHBondContact O-N 3.07Å; Y112-Y115 PolarHBondContact O-N 3.09Å; Y112-V116 HydrophobicContact CD2-CB 3.75Å; Y112-V116 HydrophobicContact CD2-CG1 4.12Å; Y112-V116 HydrophobicContact CD2-CG2 4.01Å; Y112-V116 HydrophobicContact CE2-CB 3.71Å; Y112-V116 HydrophobicContact CE2-CG1 3.57Å; Y112-V116 HydrophobicContact CE2-CG2 4.31Å; Y112-V116 HydrophobicContact CG-CB 4.43Å; Y112-V116 WeakPolarHBondContact O-CA 3.49Å; Y112-V116 WeakPolarHBondContact O-CB 3.35Å; Y112-V116 PolarHBondContact O-N 3.1Å; Y112-E117 HydrophobicContact CD1-CB 4.34Å; Y112-E117 HydrophobicContact CE1-CB 3.87Å; Y112-E117 PolarHBondContact O-N 2.88Å
113	S	91.6	Very high	89.3	Confident	12 Å²	12	38.8 Å²	38.8	8%	0.084	20%	0.196	C	C	.	.	I	π-helix	trans	-62.5	-40.2	-179.2	-169.4	0	0	0	0	112.3	I109 Y110 M111 E117 T118	I109-S113 WeakPolarHBondContact O-CB 3.29Å; I109-S113 PolarHBondContact O-N 3.19Å; Y110-S113 WeakPolarHBondContact O-CB 3.39Å; Y110-S113 PolarHBondContact O-N 2.91Å; Y110-S113 VanDerWaalsContact O-N 3.13Å; M111-S113 VanDerWaalsContact C-N 3.28Å; M111-S113 PolarHBondContact O-N 3.34Å; S113-E117 VanDerWaalsContact CB-OE2 3.27Å; S113-E117 WeakPolarHBondContact CB-OE2 3.3Å; S113-E117 PolarHBondContact OG-OE2 3.38Å; S113-T118 VanDerWaalsContact O-CB 3.26Å; S113-T118 WeakPolarHBondContact O-CB 3.37Å; S113-T118 PolarHBondContact O-N 3.11Å; S113-T118 PolarHBondContact O-OG1 3.38Å
114	I	90.9	Very high	90.8	Very high	11 Å²	11	38.1 Å²	38.1	6%	0.056	19%	0.192	C	C	.	.	I	π-helix	trans	-71.4	-50.6	178.3	-67.8	-177.2	0	0	0	111.4	Y110 M111 Y112 P119 Q180 V182	Y110-I114 HydrophobicContact CD1-CD1 3.81Å; Y110-I114 HydrophobicContact CD1-CG1 4.43Å; Y110-I114 HydrophobicContact CE1-CD1 3.23Å; Y110-I114 HydrophobicContact CE1-CG1 4.12Å; Y110-I114 PolarHBondContact O-N 3.21Å; Y110-I114 VanDerWaalsContact O-N 3.08Å; M111-I114 PolarHBondContact O-N 2.98Å; Y112-I114 VanDerWaalsContact C-N 3.32Å; Y112-I114 PolarHBondContact O-N 3.07Å; I114-P119 VanDerWaalsContact O-CD 3.28Å; I114-P119 WeakPolarHBondContact O-CD 3.49Å; I114-Q180 HydrophobicContact CD1-CB 4.41Å; I114-Q180 VanDerWaalsContact CG1-OE1 3.28Å; I114-Q180 HydrophobicContact CG2-CB 3.76Å; I114-V182 HydrophobicContact CD1-CG2 3.59Å
115	Y	93.2	Very high	91.6	Very high	82 Å²	82	34.4 Å²	34.4	32%	0.322	17%	0.172	S	C	.	.	I	π-helix	trans	-90.7	-19.5	-167.9	-67.4	-61.4	0	0	0	114.4	M111 Y112 F177 V182	M111-Y115 VanDerWaalsContact O-CD2 3.27Å; M111-Y115 WeakPolarHBondContact O-CD2 3.47Å; M111-Y115 PolarHBondContact O-N 2.97Å; Y112-Y115 PolarHBondContact O-N 3.09Å; Y115-F177 WeakPolarHBondContact O-CE1 3.37Å; Y115-V182 HydrophobicContact CE2-CB 4.18Å; Y115-V182 HydrophobicContact CE2-CG2 3.85Å; Y115-V182 PolarHBondContact OH-N 3.36Å; Y115-V182 VanDerWaalsContact OH-N 3.08Å
116	V	95.3	Very high	92.2	Very high	59 Å²	59	31.7 Å²	31.7	36%	0.358	15%	0.15	S	C	.	.	I	π-helix	trans	-123.6	-61.6	-176.4	-176	0	0	0	0	111.1	Y112 T118 P119 V120	Y112-V116 HydrophobicContact CD2-CB 3.75Å; Y112-V116 HydrophobicContact CD2-CG1 4.12Å; Y112-V116 HydrophobicContact CD2-CG2 4.01Å; Y112-V116 HydrophobicContact CE2-CB 3.71Å; Y112-V116 HydrophobicContact CE2-CG1 3.57Å; Y112-V116 HydrophobicContact CE2-CG2 4.31Å; Y112-V116 HydrophobicContact CG-CB 4.43Å; Y112-V116 WeakPolarHBondContact O-CA 3.49Å; Y112-V116 WeakPolarHBondContact O-CB 3.35Å; Y112-V116 PolarHBondContact O-N 3.1Å; V116-T118 PolarHBondContact O-N 2.97Å; V116-P119 WeakPolarHBondContact O-CD 3.5Å; V116-V120 HydrophobicContact CG1-CG2 4.31Å; V116-V120 WeakPolarHBondContact O-CB 3.42Å; V116-V120 WeakPolarHBondContact O-CG2 3.47Å; V116-V120 PolarHBondContact O-N 2.92Å
117	E	94.8	Very high	92.9	Very high	3 Å²	3	32 Å²	32	1%	0.014	15%	0.151	C	C	.	.	I	π-helix	trans	-59	-52.5	-173	-174.4	-156.4	144.9	0	0	111.6	V86 R87 Q90 Y112 S113 V120 S121	V86-E117 HydrophobicContact CG2-CG 4.46Å; R87-E117 HydrophobicContact CG-CG 4.06Å; R87-E117 IonicContact NE-OE1 3.19Å; Q90-E117 WeakPolarHBondContact CB-OE2 3.09Å; Q90-E117 WeakPolarHBondContact CG-OE1 3.25Å; Q90-E117 WeakPolarHBondContact CG-OE2 3.24Å; Q90-E117 PolarHBondContact NE2-OE1 3.22Å; Q90-E117 PolarHBondContact OE1-OE1 3.07Å; Q90-E117 VanDerWaalsContact OE1-OE1 3.1Å; Y112-E117 HydrophobicContact CD1-CB 4.34Å; Y112-E117 HydrophobicContact CE1-CB 3.87Å; Y112-E117 PolarHBondContact O-N 2.88Å; S113-E117 VanDerWaalsContact CB-OE2 3.27Å; S113-E117 WeakPolarHBondContact CB-OE2 3.3Å; S113-E117 PolarHBondContact OG-OE2 3.38Å; E117-V120 PolarHBondContact O-N 3.23Å; E117-S121 WeakPolarHBondContact O-CB 3.46Å; E117-S121 PolarHBondContact O-N 3.5Å; E117-S121 PolarHBondContact O-OG 3.49Å
118	T	92.9	Very high	93.5	Very high	46 Å²	46	31.7 Å²	31.7	28%	0.282	15%	0.149	S	C	.	.	H	α-helix	trans	-61.7	-55	-174.4	-65.1	0	0	0	0	110.9	S113 V116 V120 S121 N122 Y176	S113-T118 VanDerWaalsContact O-CB 3.26Å; S113-T118 WeakPolarHBondContact O-CB 3.37Å; S113-T118 PolarHBondContact O-N 3.11Å; S113-T118 PolarHBondContact O-OG1 3.38Å; V116-T118 PolarHBondContact O-N 2.97Å; T118-V120 PolarHBondContact O-N 3.43Å; T118-S121 PolarHBondContact O-OG 3.38Å; T118-S121 VanDerWaalsContact O-OG 3.11Å; T118-N122 WeakPolarHBondContact O-CB 3.4Å; T118-N122 PolarHBondContact O-N 3.32Å; T118-N122 VanDerWaalsContact O-N 3.16Å; T118-N122 PolarHBondContact O-ND2 3.25Å; T118-Y176 HydrophobicContact CG2-CD1 4.09Å
119	P	94.7	Very high	93.9	Very high	0 Å²	0	23.8 Å²	23.8	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-61.3	-46.8	178.1	-23.2	33.8	0	0	0	113.1	I114 V116 N122 M123 F177	I114-P119 VanDerWaalsContact O-CD 3.28Å; I114-P119 WeakPolarHBondContact O-CD 3.49Å; V116-P119 WeakPolarHBondContact O-CD 3.5Å; P119-N122 PolarHBondContact O-N 2.8Å; P119-M123 VanDerWaalsContact O-CG 3.25Å; P119-M123 WeakPolarHBondContact O-CG 3.32Å; P119-M123 PolarHBondContact O-N 3.4Å; P119-F177 HydrophobicContact CB-CD1 3.84Å; P119-F177 HydrophobicContact CB-CD2 4.19Å; P119-F177 HydrophobicContact CB-CE1 3.46Å; P119-F177 VanDerWaalsContact CB-CE1 3.46Å; P119-F177 HydrophobicContact CB-CE2 3.86Å; P119-F177 HydrophobicContact CB-CG 4.19Å; P119-F177 HydrophobicContact CB-CZ 3.47Å; P119-F177 VanDerWaalsContact CB-CZ 3.47Å; P119-F177 HydrophobicContact CG-CD1 3.57Å; P119-F177 HydrophobicContact CG-CE1 3.59Å; P119-F177 HydrophobicContact CG-CG 4.09Å; P119-F177 HydrophobicContact CG-CZ 4.13Å
120	V	96.6	Very high	94.1	Very high	35 Å²	35	25.9 Å²	25.9	21%	0.212	13%	0.125	C	C	.	.	H	α-helix	trans	-68.3	-43.8	-174.5	176.7	0	0	0	0	111.3	I82 V86 V116 E117 T118 N122 M123 T124	I82-V120 HydrophobicContact CG2-CG1 3.96Å; V86-V120 HydrophobicContact CG1-CB 4.44Å; V86-V120 HydrophobicContact CG1-CG1 3.87Å; V116-V120 HydrophobicContact CG1-CG2 4.31Å; V116-V120 WeakPolarHBondContact O-CB 3.42Å; V116-V120 WeakPolarHBondContact O-CG2 3.47Å; V116-V120 PolarHBondContact O-N 2.92Å; E117-V120 PolarHBondContact O-N 3.23Å; T118-V120 PolarHBondContact O-N 3.43Å; V120-N122 VanDerWaalsContact C-N 3.32Å; V120-N122 PolarHBondContact O-N 3.4Å; V120-M123 WeakPolarHBondContact O-CB 3.2Å; V120-M123 PolarHBondContact O-N 2.76Å; V120-M123 VanDerWaalsContact O-N 3.13Å; V120-T124 HydrophobicContact CG1-CG2 4.37Å; V120-T124 PolarHBondContact O-N 3.28Å; V120-T124 PolarHBondContact O-OG1 3.49Å; V120-T124 VanDerWaalsContact O-OG1 3.07Å
121	S	95.2	Very high	94.6	Very high	2 Å²	2	24 Å²	24	1%	0.014	12%	0.117	C	C	.	.	H	α-helix	trans	-61.5	-41	176.3	60.8	0	0	0	0	112	R87 E117 T118 M123 T124 E125	R87-S121 PolarHBondContact NH2-OG 3.16Å; E117-S121 WeakPolarHBondContact O-CB 3.46Å; E117-S121 PolarHBondContact O-N 3.5Å; E117-S121 PolarHBondContact O-OG 3.49Å; T118-S121 PolarHBondContact O-OG 3.38Å; T118-S121 VanDerWaalsContact O-OG 3.11Å; S121-M123 VanDerWaalsContact C-N 3.29Å; S121-M123 PolarHBondContact O-N 2.95Å; S121-T124 PolarHBondContact O-N 3.25Å; S121-T124 PolarHBondContact O-OG1 3.05Å; S121-E125 VanDerWaalsContact O-CB 3.27Å; S121-E125 WeakPolarHBondContact O-CB 3.38Å; S121-E125 VanDerWaalsContact O-CG 3.23Å; S121-E125 WeakPolarHBondContact O-CG 3.35Å; S121-E125 PolarHBondContact O-N 2.91Å
122	N	93.4	Very high	94.8	Very high	11 Å²	11	21.2 Å²	21.2	6%	0.059	10%	0.104	C	C	.	.	H	α-helix	trans	-66.5	-29.5	176.3	-82.1	-73.9	0	0	0	112.7	T118 P119 V120 N126 N173 Y176 R213 Y388	T118-N122 WeakPolarHBondContact O-CB 3.4Å; T118-N122 PolarHBondContact O-N 3.32Å; T118-N122 VanDerWaalsContact O-N 3.16Å; T118-N122 PolarHBondContact O-ND2 3.25Å; P119-N122 PolarHBondContact O-N 2.8Å; V120-N122 VanDerWaalsContact C-N 3.32Å; V120-N122 PolarHBondContact O-N 3.4Å; N122-N126 WeakPolarHBondContact O-CB 3.34Å; N122-N126 PolarHBondContact O-N 3.44Å; N122-N173 WeakPolarHBondContact CB-OD1 3.44Å; N122-N173 PolarHBondContact O-ND2 3.43Å; N122-N173 PolarHBondContact O-OD1 3.09Å; N122-Y176 HydrophobicContact CB-CD2 4.47Å; N122-Y176 HydrophobicContact CB-CE2 4.43Å; N122-R213 PolarHBondContact OD1-NH2 2.84Å; N122-Y388 PolarHBondContact OD1-OH 3.49Å
123	M	96.1	Very high	94.9	Very high	7 Å²	7	18.2 Å²	18.2	3%	0.034	9%	0.093	C	C	.	.	H	α-helix	trans	-70.2	-51	172.2	-70	164.5	177.6	0	0	111.4	P119 V120 S121 N126 I127 F170 N173 F177	P119-M123 VanDerWaalsContact O-CG 3.25Å; P119-M123 WeakPolarHBondContact O-CG 3.32Å; P119-M123 PolarHBondContact O-N 3.4Å; V120-M123 WeakPolarHBondContact O-CB 3.2Å; V120-M123 PolarHBondContact O-N 2.76Å; V120-M123 VanDerWaalsContact O-N 3.13Å; S121-M123 VanDerWaalsContact C-N 3.29Å; S121-M123 PolarHBondContact O-N 2.95Å; M123-N126 WeakPolarHBondContact O-CB 3.34Å; M123-N126 PolarHBondContact O-N 3.37Å; M123-I127 WeakPolarHBondContact O-CG1 3.37Å; M123-I127 PolarHBondContact O-N 2.72Å; M123-F170 HydrophobicContact CB-CD1 4.42Å; M123-F170 HydrophobicContact CB-CE1 4.37Å; M123-F170 HydrophobicContact CE-CD1 4.15Å; M123-F170 HydrophobicContact CG-CD1 4.11Å; M123-F170 HydrophobicContact CG-CE1 4.43Å; M123-F170 HydrophobicContact SD-CD1 3.37Å; M123-F170 WeakPolarHBondContact SD-CD1 3.46Å; M123-F170 HydrophobicContact SD-CE1 3.6Å; M123-F170 VanDerWaalsContact SD-CE1 3.6Å; M123-F170 HydrophobicContact SD-CG 4.49Å; M123-N173 HydrophobicContact CB-CB 4.49Å; M123-N173 HydrophobicContact CE-CB 3.87Å; M123-N173 HydrophobicContact CG-CB 3.39Å; M123-F177 HydrophobicContact CE-CD2 4.46Å; M123-F177 HydrophobicContact CE-CE2 3.46Å; M123-F177 VanDerWaalsContact CE-CE2 3.46Å; M123-F177 HydrophobicContact CE-CZ 3.98Å
124	T	97.1	Very high	95.1	Very high	5 Å²	5	18 Å²	18	3%	0.031	9%	0.092	C	C	.	.	H	α-helix	trans	-71.8	-36.5	-174.7	53.1	0	0	0	0	112.4	I82 T83 V120 S121 N126 I127 S128	I82-T124 HydrophobicContact CB-CG2 3.94Å; I82-T124 HydrophobicContact CG2-CG2 3.66Å; T83-T124 WeakPolarHBondContact OG1-CB 3.47Å; T83-T124 PolarHBondContact OG1-OG1 3.38Å; V120-T124 HydrophobicContact CG1-CG2 4.37Å; V120-T124 PolarHBondContact O-N 3.28Å; V120-T124 PolarHBondContact O-OG1 3.49Å; V120-T124 VanDerWaalsContact O-OG1 3.07Å; S121-T124 PolarHBondContact O-N 3.25Å; S121-T124 PolarHBondContact O-OG1 3.05Å; T124-N126 VanDerWaalsContact C-N 3.3Å; T124-N126 PolarHBondContact O-N 3.43Å; T124-I127 WeakPolarHBondContact O-CB 3.22Å; T124-I127 PolarHBondContact O-N 2.92Å; T124-S128 PolarHBondContact O-N 3.09Å; T124-S128 PolarHBondContact O-OG 3.47Å
125	E	94.9	Very high	95.2	Very high	7 Å²	7	17.6 Å²	17.6	3%	0.033	9%	0.089	C	C	.	.	H	α-helix	trans	-60.2	-40.4	170.9	-76.3	176.5	-175.9	0	0	111.8	T83 R87 S121 S128 A129 Q384 F424	T83-E125 HydrophobicContact CG2-CG 3.75Å; R87-E125 IonicContact CZ-OE1 3.51Å; R87-E125 IonicContact NH1-OE1 3.11Å; R87-E125 PolarHBondContact NH1-OE1 3.3Å; R87-E125 IonicContact NH2-OE1 3.56Å; R87-E125 PolarHBondContact NH2-OE1 3.43Å; S121-E125 VanDerWaalsContact O-CB 3.27Å; S121-E125 WeakPolarHBondContact O-CB 3.38Å; S121-E125 VanDerWaalsContact O-CG 3.23Å; S121-E125 WeakPolarHBondContact O-CG 3.35Å; S121-E125 PolarHBondContact O-N 2.91Å; E125-S128 PolarHBondContact O-N 3.35Å; E125-A129 WeakPolarHBondContact O-CB 3.33Å; E125-A129 PolarHBondContact O-N 2.89Å; E125-Q384 PolarHBondContact OE1-NE2 3.12Å; E125-F424 HydrophobicContact CG-CE2 4.45Å; E125-F424 HydrophobicContact CG-CZ 4.32Å
126	N	94.8	Very high	95.2	Very high	3 Å²	3	13.7 Å²	13.7	2%	0.016	7%	0.074	C	C	.	.	H	α-helix	trans	-65.8	-41.3	176.8	-171.2	20.1	0	0	0	111.3	N122 M123 T124 A129 W130 A169 N173 V217	N122-N126 WeakPolarHBondContact O-CB 3.34Å; N122-N126 PolarHBondContact O-N 3.44Å; M123-N126 WeakPolarHBondContact O-CB 3.34Å; M123-N126 PolarHBondContact O-N 3.37Å; T124-N126 VanDerWaalsContact C-N 3.3Å; T124-N126 PolarHBondContact O-N 3.43Å; N126-A129 PolarHBondContact O-N 3.49Å; N126-W130 PolarHBondContact O-N 3.29Å; N126-W130 VanDerWaalsContact O-N 3.1Å; N126-W130 PolarHBondContact OD1-NE1 3.26Å; N126-A169 HydrophobicContact CB-CB 4.18Å; N126-N173 PolarHBondContact ND2-ND2 3.24Å; N126-V217 HydrophobicContact CB-CG1 3.88Å; N126-V217 WeakPolarHBondContact OD1-CG1 3.34Å
127	I	97.1	Very high	95.1	Very high	10 Å²	10	14 Å²	14	5%	0.051	7%	0.073	C	C	.	.	H	α-helix	trans	-58.4	-50.8	171.8	-67.2	169.2	0	0	0	109.8	A79 M123 T124 A129 W130 L131 C166 A169 F170	A79-I127 HydrophobicContact CB-CB 4.31Å; A79-I127 HydrophobicContact CB-CG2 3.91Å; M123-I127 WeakPolarHBondContact O-CG1 3.37Å; M123-I127 PolarHBondContact O-N 2.72Å; T124-I127 WeakPolarHBondContact O-CB 3.22Å; T124-I127 PolarHBondContact O-N 2.92Å; I127-A129 VanDerWaalsContact C-N 3.32Å; I127-A129 PolarHBondContact O-N 3.32Å; I127-W130 PolarHBondContact O-N 3.3Å; I127-L131 HydrophobicContact CG2-CD1 3.54Å; I127-L131 HydrophobicContact CG2-CG 4.04Å; I127-L131 WeakPolarHBondContact O-CB 3.06Å; I127-L131 VanDerWaalsContact O-CG 3.23Å; I127-L131 WeakPolarHBondContact O-CG 3.34Å; I127-L131 PolarHBondContact O-N 2.85Å; I127-C166 HydrophobicContact CD1-CB 4.37Å; I127-A169 HydrophobicContact CD1-CB 4.3Å; I127-A169 HydrophobicContact CG1-CB 3.49Å; I127-A169 VanDerWaalsContact CG1-CB 3.49Å; I127-F170 HydrophobicContact CD1-CE2 4.19Å
128	S	96.2	Very high	95.1	Very high	0 Å²	0	14 Å²	14	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-58.3	-42.1	179.3	-67.2	0	0	0	0	112.2	A79 D80 T124 E125 T132	A79-S128 VanDerWaalsContact CB-OG 3.32Å; A79-S128 WeakPolarHBondContact CB-OG 3.36Å; D80-S128 WeakPolarHBondContact OD1-CB 3.4Å; D80-S128 PolarHBondContact OD1-OG 3.35Å; T124-S128 PolarHBondContact O-N 3.09Å; T124-S128 PolarHBondContact O-OG 3.47Å; E125-S128 PolarHBondContact O-N 3.35Å; S128-T132 WeakPolarHBondContact O-CB 3.36Å; S128-T132 PolarHBondContact O-N 2.87Å; S128-T132 PolarHBondContact O-OG1 3.3Å
129	A	94.5	Very high	95	Very high	5 Å²	5	12 Å²	12	4%	0.041	6%	0.061	C	C	.	.	H	α-helix	trans	-60.7	-51.5	177.4	0	0	0	0	0	112.4	E125 N126 I127 T132 V133 P221 F377	E125-A129 WeakPolarHBondContact O-CB 3.33Å; E125-A129 PolarHBondContact O-N 2.89Å; N126-A129 PolarHBondContact O-N 3.49Å; I127-A129 VanDerWaalsContact C-N 3.32Å; I127-A129 PolarHBondContact O-N 3.32Å; A129-T132 WeakPolarHBondContact O-CB 3.3Å; A129-T132 PolarHBondContact O-N 3.45Å; A129-V133 PolarHBondContact O-N 3.09Å; A129-P221 HydrophobicContact CB-CB 4.38Å; A129-F377 HydrophobicContact CB-CZ 3.79Å
130	W	96.4	Very high	94.8	Very high	78 Å²	78	15 Å²	15	30%	0.295	7%	0.072	S	C	.	.	H	α-helix	trans	-72.8	-31.3	-178.6	-78.1	107.4	0	0	0	113.7	N126 I127 T132 V133 A134 I165 F216 I220 P221	N126-W130 PolarHBondContact O-N 3.29Å; N126-W130 VanDerWaalsContact O-N 3.1Å; N126-W130 PolarHBondContact OD1-NE1 3.26Å; I127-W130 PolarHBondContact O-N 3.3Å; W130-T132 VanDerWaalsContact C-N 3.29Å; W130-V133 HydrophobicContact CE3-CB 4.13Å; W130-V133 HydrophobicContact CE3-CG1 4.05Å; W130-V133 HydrophobicContact CE3-CG2 4.35Å; W130-V133 HydrophobicContact CZ3-CG1 4.12Å; W130-V133 PolarHBondContact O-N 3.34Å; W130-A134 WeakPolarHBondContact O-CB 3.47Å; W130-A134 PolarHBondContact O-N 3.43Å; W130-I165 HydrophobicContact CB-CD1 4.33Å; W130-I165 HydrophobicContact CB-CG1 4.31Å; W130-I165 HydrophobicContact CB-CG2 3.75Å; W130-F216 WeakPolarHBondContact CZ2-O 3.35Å; W130-I220 HydrophobicContact CH2-CG2 4.1Å; W130-P221 HydrophobicContact CD2-CG 4.47Å; W130-P221 HydrophobicContact CH2-CG 4.4Å; W130-P221 HydrophobicContact CZ2-CG 3.94Å
131	L	96.8	Very high	94.5	Very high	0 Å²	0	14.7 Å²	14.7	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-64.2	-37.6	169.8	-71.4	177.7	0	0	0	111.3	L72 V75 L76 I127 A134 L135 I162 I165	L72-L131 HydrophobicContact CD2-CD2 3.74Å; V75-L131 HydrophobicContact CB-CD1 3.93Å; V75-L131 HydrophobicContact CG1-CD1 3.78Å; L76-L131 HydrophobicContact CB-CD1 4.25Å; L76-L131 HydrophobicContact CD1-CB 4.36Å; I127-L131 HydrophobicContact CG2-CD1 3.54Å; I127-L131 HydrophobicContact CG2-CG 4.04Å; I127-L131 WeakPolarHBondContact O-CB 3.06Å; I127-L131 VanDerWaalsContact O-CG 3.23Å; I127-L131 WeakPolarHBondContact O-CG 3.34Å; I127-L131 PolarHBondContact O-N 2.85Å; L131-A134 PolarHBondContact O-N 3.06Å; L131-L135 WeakPolarHBondContact O-CB 3.16Å; L131-L135 VanDerWaalsContact O-CG 3.32Å; L131-L135 WeakPolarHBondContact O-CG 3.21Å; L131-L135 PolarHBondContact O-N 3.47Å; L131-I162 HydrophobicContact CD2-CG1 3.9Å; L131-I165 HydrophobicContact CD2-CD1 4.03Å
132	T	95.3	Very high	94.3	Very high	1 Å²	1	15 Å²	15	1%	0.006	7%	0.072	C	C	.	.	H	α-helix	trans	-65.7	-40.2	175.4	-56.8	0	0	0	0	111.2	S128 A129 W130 L135 A136 L225 I374 F377	S128-T132 WeakPolarHBondContact O-CB 3.36Å; S128-T132 PolarHBondContact O-N 2.87Å; S128-T132 PolarHBondContact O-OG1 3.3Å; A129-T132 WeakPolarHBondContact O-CB 3.3Å; A129-T132 PolarHBondContact O-N 3.45Å; W130-T132 VanDerWaalsContact C-N 3.29Å; T132-L135 WeakPolarHBondContact O-CB 3.42Å; T132-L135 PolarHBondContact O-N 3.26Å; T132-A136 PolarHBondContact O-N 3.5Å; T132-L225 HydrophobicContact CG2-CD1 3.72Å; T132-L225 HydrophobicContact CG2-CD2 3.89Å; T132-L225 HydrophobicContact CG2-CG 4.47Å; T132-I374 HydrophobicContact CG2-CB 4.2Å; T132-I374 HydrophobicContact CG2-CG1 3.8Å; T132-I374 HydrophobicContact CG2-CG2 3.78Å; T132-F377 HydrophobicContact CG2-CB 4.45Å; T132-F377 HydrophobicContact CG2-CD1 4.28Å; T132-F377 HydrophobicContact CG2-CG 4.23Å
133	V	95	Very high	93.9	Very high	6 Å²	6	16.4 Å²	16.4	4%	0.036	8%	0.079	C	C	.	.	H	α-helix	trans	-61.3	-47.9	171.5	168.4	0	0	0	0	111.2	A129 W130 L135 A136 I137 P221 F224 L225	A129-V133 PolarHBondContact O-N 3.09Å; W130-V133 HydrophobicContact CE3-CB 4.13Å; W130-V133 HydrophobicContact CE3-CG1 4.05Å; W130-V133 HydrophobicContact CE3-CG2 4.35Å; W130-V133 HydrophobicContact CZ3-CG1 4.12Å; W130-V133 PolarHBondContact O-N 3.34Å; V133-L135 VanDerWaalsContact C-N 3.29Å; V133-L135 PolarHBondContact O-N 2.95Å; V133-A136 WeakPolarHBondContact O-CB 3Å; V133-A136 PolarHBondContact O-N 2.97Å; V133-A136 VanDerWaalsContact O-N 3.14Å; V133-I137 HydrophobicContact CG1-CD1 3.9Å; V133-I137 WeakPolarHBondContact O-CG1 3.39Å; V133-I137 PolarHBondContact O-N 3.39Å; V133-P221 HydrophobicContact CG2-CB 3.99Å; V133-F224 HydrophobicContact CB-CD1 4.28Å; V133-F224 HydrophobicContact CG1-CD1 3.63Å; V133-F224 HydrophobicContact CG1-CE1 3.77Å; V133-F224 HydrophobicContact CG1-CG 4.3Å; V133-F224 HydrophobicContact CG2-CD1 4.08Å; V133-L225 HydrophobicContact CB-CD2 4.44Å; V133-L225 HydrophobicContact CG2-CD1 4.41Å; V133-L225 HydrophobicContact CG2-CD2 3.9Å; V133-L225 HydrophobicContact CG2-CG 3.91Å
134	A	95.6	Very high	93.4	Very high	8 Å²	8	21.4 Å²	21.4	7%	0.066	10%	0.101	C	C	.	.	H	α-helix	trans	-60.5	-39.3	177.7	0	0	0	0	0	111.9	L72 W130 L131 I137 E138 L161 I165	L72-A134 HydrophobicContact CD1-CB 4.25Å; L72-A134 HydrophobicContact CD2-CB 4.1Å; W130-A134 WeakPolarHBondContact O-CB 3.47Å; W130-A134 PolarHBondContact O-N 3.43Å; L131-A134 PolarHBondContact O-N 3.06Å; A134-I137 PolarHBondContact O-N 3.02Å; A134-E138 WeakPolarHBondContact O-CB 3.41Å; A134-E138 PolarHBondContact O-N 2.92Å; A134-L161 HydrophobicContact CB-CD2 4.04Å; A134-I165 HydrophobicContact CB-CD1 4.34Å
135	L	94.1	Very high	92.9	Very high	1 Å²	1	25 Å²	25	1%	0.005	12%	0.117	C	C	.	.	H	α-helix	trans	-61.2	-45.9	173	-80.1	168.8	0	0	0	111.7	A69 L72 M73 L76 L131 T132 V133 E138 R139 L370	A69-L135 HydrophobicContact CB-CD2 4.21Å; A69-L135 WeakPolarHBondContact O-CD2 3.25Å; L72-L135 HydrophobicContact CB-CD1 4.44Å; L72-L135 HydrophobicContact CB-CD2 3.56Å; L72-L135 HydrophobicContact CB-CG 3.8Å; L72-L135 HydrophobicContact CD1-CD2 3.84Å; L72-L135 HydrophobicContact CD1-CG 4.07Å; L72-L135 HydrophobicContact CG-CD2 4.35Å; M73-L135 HydrophobicContact CG-CD1 4.14Å; M73-L135 HydrophobicContact CG-CD2 4.02Å; L76-L135 HydrophobicContact CD2-CD1 3.77Å; L131-L135 WeakPolarHBondContact O-CB 3.16Å; L131-L135 VanDerWaalsContact O-CG 3.32Å; L131-L135 WeakPolarHBondContact O-CG 3.21Å; L131-L135 PolarHBondContact O-N 3.47Å; T132-L135 WeakPolarHBondContact O-CB 3.42Å; T132-L135 PolarHBondContact O-N 3.26Å; V133-L135 VanDerWaalsContact C-N 3.29Å; V133-L135 PolarHBondContact O-N 2.95Å; L135-E138 PolarHBondContact O-N 3.34Å; L135-R139 WeakPolarHBondContact O-CB 3.2Å; L135-R139 VanDerWaalsContact O-CG 3.29Å; L135-R139 WeakPolarHBondContact O-CG 3.47Å; L135-R139 PolarHBondContact O-N 3.41Å; L135-L370 HydrophobicContact CD1-CD2 4.15Å; L135-L370 HydrophobicContact CD2-CD1 4.44Å; L135-L370 HydrophobicContact CD2-CD2 3.97Å; L135-L370 HydrophobicContact CG-CD2 4.48Å
136	A	93.4	Very high	92.5	Very high	0 Å²	0	29.6 Å²	29.6	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-60.9	-45.7	177.9	0	0	0	0	0	111.8	T132 V133 R139 Y140 F224 L225 L232 I374	T132-A136 PolarHBondContact O-N 3.5Å; V133-A136 WeakPolarHBondContact O-CB 3Å; V133-A136 PolarHBondContact O-N 2.97Å; V133-A136 VanDerWaalsContact O-N 3.14Å; A136-R139 PolarHBondContact O-N 2.89Å; A136-Y140 WeakPolarHBondContact O-CB 3.48Å; A136-Y140 PolarHBondContact O-N 3.36Å; A136-F224 HydrophobicContact CB-CE1 4.31Å; A136-L225 HydrophobicContact CB-CD2 3.99Å; A136-L232 HydrophobicContact CB-CD1 4.39Å; A136-I374 HydrophobicContact CB-CD1 3.96Å
137	I	92.9	Very high	92.2	Very high	65 Å²	65	33.3 Å²	33.3	33%	0.333	16%	0.16	S	C	.	.	H	α-helix	trans	-61.7	-50.5	176.3	-64.7	166.5	0	0	0	110.4	V133 A134 R139 Y140 V141 F153 F224	V133-I137 HydrophobicContact CG1-CD1 3.9Å; V133-I137 WeakPolarHBondContact O-CG1 3.39Å; V133-I137 PolarHBondContact O-N 3.39Å; A134-I137 PolarHBondContact O-N 3.02Å; I137-R139 VanDerWaalsContact C-N 3.26Å; I137-R139 PolarHBondContact O-N 3.22Å; I137-Y140 PolarHBondContact O-N 3.37Å; I137-V141 HydrophobicContact CG2-CG2 4.21Å; I137-V141 WeakPolarHBondContact O-CG2 3.38Å; I137-V141 PolarHBondContact O-N 3.34Å; I137-F153 HydrophobicContact CG2-CZ 3.97Å; I137-F224 HydrophobicContact CD1-CE1 4.18Å; I137-F224 HydrophobicContact CD1-CZ 3.87Å; I137-F224 HydrophobicContact CG1-CE1 3.69Å; I137-F224 HydrophobicContact CG1-CE2 4.45Å; I137-F224 HydrophobicContact CG1-CZ 3.39Å
138	E	93.4	Very high	91.8	Very high	5 Å²	5	36.6 Å²	36.6	2%	0.023	18%	0.178	C	C	.	.	H	α-helix	trans	-59.4	-39.7	-177.8	-172.3	-85.6	173.6	0	0	111.4	L72 A134 L135 S142 F153	L72-E138 HydrophobicContact CD1-CB 4.38Å; A134-E138 WeakPolarHBondContact O-CB 3.41Å; A134-E138 PolarHBondContact O-N 2.92Å; L135-E138 PolarHBondContact O-N 3.34Å; E138-S142 WeakPolarHBondContact O-CB 3.49Å; E138-S142 PolarHBondContact O-N 2.88Å; E138-S142 PolarHBondContact O-OG 3.2Å; E138-S142 PolarHBondContact OE1-OG 3.09Å; E138-F153 HydrophobicContact CB-CD1 3.85Å; E138-F153 HydrophobicContact CB-CD2 4.42Å; E138-F153 HydrophobicContact CB-CE1 3.55Å; E138-F153 HydrophobicContact CB-CE2 4.17Å; E138-F153 HydrophobicContact CB-CG 4.28Å; E138-F153 HydrophobicContact CB-CZ 3.73Å; E138-F153 HydrophobicContact CG-CB 4.12Å; E138-F153 HydrophobicContact CG-CD1 3.38Å; E138-F153 HydrophobicContact CG-CD2 3.96Å; E138-F153 HydrophobicContact CG-CE1 3.67Å; E138-F153 HydrophobicContact CG-CE2 4.22Å; E138-F153 HydrophobicContact CG-CG 3.54Å; E138-F153 HydrophobicContact CG-CZ 4.08Å
139	R	91.6	Very high	91.5	Very high	4 Å²	4	37.2 Å²	37.2	2%	0.015	18%	0.182	C	C	.	.	H	α-helix	trans	-65.4	-48.7	174.2	-76.1	-57.5	103.4	-166.8	-8.1	112.6	L135 A136 I137 V141 S142 M143 L232 L366 L370	L135-R139 WeakPolarHBondContact O-CB 3.2Å; L135-R139 VanDerWaalsContact O-CG 3.29Å; L135-R139 WeakPolarHBondContact O-CG 3.47Å; L135-R139 PolarHBondContact O-N 3.41Å; A136-R139 PolarHBondContact O-N 2.89Å; I137-R139 VanDerWaalsContact C-N 3.26Å; I137-R139 PolarHBondContact O-N 3.22Å; R139-V141 VanDerWaalsContact C-N 3.35Å; R139-V141 PolarHBondContact O-N 3.04Å; R139-S142 PolarHBondContact O-N 3.43Å; R139-M143 WeakPolarHBondContact O-CG 3.46Å; R139-M143 PolarHBondContact O-N 3.2Å; R139-L232 HydrophobicContact CB-CD1 4.39Å; R139-L232 HydrophobicContact CB-CD2 4Å; R139-L366 VanDerWaalsContact NH1-CD2 3.26Å; R139-L370 HydrophobicContact CG-CB 4.07Å; R139-L370 HydrophobicContact CG-CD1 3.45Å; R139-L370 VanDerWaalsContact CG-CD1 3.45Å; R139-L370 HydrophobicContact CG-CG 4.36Å
140	Y	89.6	Confident	91.2	Very high	62 Å²	62	43.1 Å²	43.1	24%	0.243	21%	0.207	C	C	.	.	H	α-helix	trans	-59	-48.9	-179.1	-179.4	-94.6	0	0	0	110.9	A136 I137 M143 K144 L231 L232 L235	A136-Y140 WeakPolarHBondContact O-CB 3.48Å; A136-Y140 PolarHBondContact O-N 3.36Å; I137-Y140 PolarHBondContact O-N 3.37Å; Y140-M143 PolarHBondContact O-N 3.5Å; Y140-K144 HydrophobicContact CE1-CD 3.75Å; Y140-K144 HydrophobicContact CE2-CD 4.29Å; Y140-K144 VanDerWaalsContact CZ-CD 3.5Å; Y140-K144 WeakPolarHBondContact O-CB 3.23Å; Y140-K144 PolarHBondContact O-N 3.33Å; Y140-K144 VanDerWaalsContact OH-CD 3.22Å; Y140-K144 WeakPolarHBondContact OH-CD 3.35Å; Y140-K144 PolarHBondContact OH-NZ 3Å; Y140-L231 HydrophobicContact CD2-CB 4.44Å; Y140-L231 HydrophobicContact CE2-CB 4.19Å; Y140-L232 HydrophobicContact CD2-CD2 4.39Å; Y140-L235 HydrophobicContact CD2-CD1 4.4Å; Y140-L235 HydrophobicContact CE2-CD1 4.28Å
141	V	91.2	Very high	91	Very high	28 Å²	28	48.5 Å²	48.5	17%	0.17	23%	0.227	C	C	.	.	H	α-helix	trans	-64.9	-42.4	178.2	179.3	0	0	0	0	110.8	I137 R139 M143 H145 L148 F153	I137-V141 HydrophobicContact CG2-CG2 4.21Å; I137-V141 WeakPolarHBondContact O-CG2 3.38Å; I137-V141 PolarHBondContact O-N 3.34Å; R139-V141 VanDerWaalsContact C-N 3.35Å; R139-V141 PolarHBondContact O-N 3.04Å; V141-M143 VanDerWaalsContact C-N 3.28Å; V141-M143 PolarHBondContact O-N 3.48Å; V141-H145 HydrophobicContact CG1-CB 4.4Å; V141-H145 CarbonylContact O-C 3.55Å; V141-H145 VanDerWaalsContact O-CA 3.3Å; V141-H145 WeakPolarHBondContact O-CA 3.32Å; V141-H145 PolarHBondContact O-N 3.28Å; V141-H145 VanDerWaalsContact O-O 3.08Å; V141-L148 HydrophobicContact CG1-CB 4.23Å; V141-F153 HydrophobicContact CB-CD2 4.48Å; V141-F153 HydrophobicContact CB-CE2 3.93Å; V141-F153 HydrophobicContact CG1-CD2 4.38Å; V141-F153 HydrophobicContact CG1-CE2 4.12Å; V141-F153 HydrophobicContact CG2-CE2 4.17Å
142	S	90.7	Very high	90.7	Very high	9 Å²	9	54.6 Å²	54.6	6%	0.063	25%	0.251	C	S	.	.	H	α-helix	trans	-63.2	-31.3	178.7	-64.8	0	0	0	0	113.9	E138 R139 S149	E138-S142 WeakPolarHBondContact O-CB 3.49Å; E138-S142 PolarHBondContact O-N 2.88Å; E138-S142 PolarHBondContact O-OG 3.2Å; E138-S142 PolarHBondContact OE1-OG 3.09Å; R139-S142 PolarHBondContact O-N 3.43Å; S142-S149 PolarHBondContact OG-OG 3.22Å
143	M	85.1	Confident	90.6	Very high	41 Å²	41	56.6 Å²	56.6	20%	0.202	26%	0.259	C	S	.	.	H	α-helix	trans	-86.4	-42.6	178.3	-68.3	-173.3	81.2	0	0	113.5	R139 Y140 V141 L235 V236 T367	R139-M143 WeakPolarHBondContact O-CG 3.46Å; R139-M143 PolarHBondContact O-N 3.2Å; Y140-M143 PolarHBondContact O-N 3.5Å; V141-M143 VanDerWaalsContact C-N 3.28Å; V141-M143 PolarHBondContact O-N 3.48Å; M143-L235 HydrophobicContact CB-CD1 4.38Å; M143-L235 HydrophobicContact CB-CD2 3.66Å; M143-L235 HydrophobicContact CE-CD2 3.25Å; M143-L235 HydrophobicContact CG-CD2 4.29Å; M143-L235 HydrophobicContact SD-CD2 3.63Å; M143-V236 HydrophobicContact CE-CG2 3.75Å; M143-V236 HydrophobicContact SD-CG2 4.21Å; M143-T367 HydrophobicContact CE-CG2 4.23Å; M143-T367 HydrophobicContact SD-CG2 3.3Å; M143-T367 WeakPolarHBondContact SD-CG2 3.5Å; M143-T367 PolarHBondContact SD-OG1 3.19Å
144	K	85.8	Confident	90.5	Very high	112 Å²	112	58.9 Å²	58.9	49%	0.487	27%	0.274	S	S	.	.	H	α-helix	trans	-86	-42	-176	-167.8	-179.4	176.2	-166	0	112.7	Y140 L235	Y140-K144 HydrophobicContact CE1-CD 3.75Å; Y140-K144 HydrophobicContact CE2-CD 4.29Å; Y140-K144 VanDerWaalsContact CZ-CD 3.5Å; Y140-K144 WeakPolarHBondContact O-CB 3.23Å; Y140-K144 PolarHBondContact O-N 3.33Å; Y140-K144 VanDerWaalsContact OH-CD 3.22Å; Y140-K144 WeakPolarHBondContact OH-CD 3.35Å; Y140-K144 PolarHBondContact OH-NZ 3Å; K144-L235 HydrophobicContact CB-CD1 4.02Å
145	H	87.7	Confident	90.5	Very high	79 Å²	79	65.3 Å²	65.3	37%	0.366	30%	0.296	S	S	.	.			trans	-128.5	66.5	-172.6	-59.8	-68.8	0	0	0	111	V141 S147 L148 S149	V141-H145 HydrophobicContact CG1-CB 4.4Å; V141-H145 CarbonylContact O-C 3.55Å; V141-H145 VanDerWaalsContact O-CA 3.3Å; V141-H145 WeakPolarHBondContact O-CA 3.32Å; V141-H145 PolarHBondContact O-N 3.28Å; V141-H145 VanDerWaalsContact O-O 3.08Å; H145-S147 VanDerWaalsContact C-N 3.31Å; H145-S147 PolarHBondContact O-N 3.42Å; H145-L148 HydrophobicContact CB-CB 4.02Å; H145-L148 HydrophobicContact CB-CD2 4.3Å; H145-L148 WeakPolarHBondContact O-CB 3.14Å; H145-L148 PolarHBondContact O-N 3.13Å; H145-L148 VanDerWaalsContact O-N 3.07Å; H145-S149 PolarHBondContact O-N 2.96Å
146	W	86.3	Confident	90.5	Very high	104 Å²	104	72.4 Å²	72.4	39%	0.394	33%	0.327	S	S	.	.	H	α-helix	trans	-55.2	-39.5	-174.4	175.8	69.4	0	0	0	114.6	S149 K150	W146-S149 PolarHBondContact O-N 3.46Å; W146-K150 HydrophobicContact CD2-CD 4.46Å; W146-K150 HydrophobicContact CH2-CD 4.15Å; W146-K150 HydrophobicContact CZ2-CD 3.78Å; W146-K150 PolarHBondContact O-N 3.4Å; W146-K150 VanDerWaalsContact O-N 3.15Å
147	S	88.3	Confident	90.7	Very high	81 Å²	81	75.3 Å²	75.3	57%	0.566	35%	0.345	S	S	*	.	H	α-helix	trans	-63.1	-43.4	176.8	50.6	0	0	0	0	111.8	H145 K150 R151	H145-S147 VanDerWaalsContact C-N 3.31Å; H145-S147 PolarHBondContact O-N 3.42Å; S147-K150 PolarHBondContact O-N 3.32Å; S147-R151 PolarHBondContact O-N 3.39Å
148	L	88.7	Confident	90.9	Very high	80 Å²	80	72.3 Å²	72.3	42%	0.419	33%	0.329	S	S	.	.	H	α-helix	trans	-65.1	-40.2	174.8	-86.8	65.7	0	0	0	111.4	V141 H145 K150 R151 Y152	V141-L148 HydrophobicContact CG1-CB 4.23Å; H145-L148 HydrophobicContact CB-CB 4.02Å; H145-L148 HydrophobicContact CB-CD2 4.3Å; H145-L148 WeakPolarHBondContact O-CB 3.14Å; H145-L148 PolarHBondContact O-N 3.13Å; H145-L148 VanDerWaalsContact O-N 3.07Å; L148-K150 VanDerWaalsContact C-N 3.3Å; L148-K150 PolarHBondContact O-N 2.95Å; L148-R151 PolarHBondContact O-N 3.19Å; L148-Y152 HydrophobicContact CB-CD2 4.2Å; L148-Y152 HydrophobicContact CB-CE2 4.49Å; L148-Y152 HydrophobicContact CG-CD2 4.43Å; L148-Y152 HydrophobicContact CG-CE2 4.22Å; L148-Y152 WeakPolarHBondContact O-CD2 3.45Å; L148-Y152 PolarHBondContact O-N 2.9Å
149	S	89.1	Confident	91.1	Very high	13 Å²	13	79.9 Å²	79.9	9%	0.091	36%	0.358	C	S	.	.	H	α-helix	trans	-57.4	-44.8	177	170.1	0	0	0	0	111.6	S142 H145 W146 R151 Y152 F153	S142-S149 PolarHBondContact OG-OG 3.22Å; H145-S149 PolarHBondContact O-N 2.96Å; W146-S149 PolarHBondContact O-N 3.46Å; S149-R151 VanDerWaalsContact C-N 3.26Å; S149-R151 PolarHBondContact O-N 3.4Å; S149-Y152 PolarHBondContact O-N 3.39Å; S149-F153 WeakPolarHBondContact O-CA 3.42Å; S149-F153 WeakPolarHBondContact O-CB 3.41Å; S149-F153 PolarHBondContact O-N 2.93Å
150	K	88.7	Confident	91.4	Very high	129 Å²	129	84.8 Å²	84.8	56%	0.561	38%	0.381	S	S	*	.	H	α-helix	trans	-61	-33.8	175.3	-78.3	-178.8	154.6	-171.6	0	113.7	W146 S147 L148	W146-K150 HydrophobicContact CD2-CD 4.46Å; W146-K150 HydrophobicContact CH2-CD 4.15Å; W146-K150 HydrophobicContact CZ2-CD 3.78Å; W146-K150 PolarHBondContact O-N 3.4Å; W146-K150 VanDerWaalsContact O-N 3.15Å; S147-K150 PolarHBondContact O-N 3.32Å; L148-K150 VanDerWaalsContact C-N 3.3Å; L148-K150 PolarHBondContact O-N 2.95Å
151	R	90.9	Very high	91.8	Very high	190 Å²	190	85 Å²	85	72%	0.717	39%	0.386	S	S	*	.	H	α-helix	trans	-76.9	-43.4	-179.5	-174.6	175.3	178	175.5	-0.8	112.3	S147 L148 S149	S147-R151 PolarHBondContact O-N 3.39Å; L148-R151 PolarHBondContact O-N 3.19Å; S149-R151 VanDerWaalsContact C-N 3.26Å; S149-R151 PolarHBondContact O-N 3.4Å
152	Y	90.9	Very high	92.1	Very high	129 Å²	129	84.4 Å²	84.4	51%	0.506	38%	0.381	S	S	.	.	H	α-helix	trans	-96.5	-39.1	-172.4	-69.5	-71.5	0	0	0	113.7	L148 S149 T154 T157	L148-Y152 HydrophobicContact CB-CD2 4.2Å; L148-Y152 HydrophobicContact CB-CE2 4.49Å; L148-Y152 HydrophobicContact CG-CD2 4.43Å; L148-Y152 HydrophobicContact CG-CE2 4.22Å; L148-Y152 WeakPolarHBondContact O-CD2 3.45Å; L148-Y152 PolarHBondContact O-N 2.9Å; S149-Y152 PolarHBondContact O-N 3.39Å; Y152-T154 VanDerWaalsContact C-N 3.25Å; Y152-T154 PolarHBondContact O-N 3.46Å; Y152-T154 VanDerWaalsContact O-N 3.14Å; Y152-T157 VanDerWaalsContact O-CB 3.3Å; Y152-T157 WeakPolarHBondContact O-CB 3.47Å; Y152-T157 WeakPolarHBondContact O-CG2 3.38Å
153	F	92.9	Very high	92.5	Very high	42 Å²	42	86.2 Å²	86.2	18%	0.184	40%	0.397	C	S	.	.	S	Bend	trans	-92.1	52.6	-179.4	-69.5	-73.7	0	0	0	112.1	I137 E138 V141 S149	I137-F153 HydrophobicContact CG2-CZ 3.97Å; E138-F153 HydrophobicContact CB-CD1 3.85Å; E138-F153 HydrophobicContact CB-CD2 4.42Å; E138-F153 HydrophobicContact CB-CE1 3.55Å; E138-F153 HydrophobicContact CB-CE2 4.17Å; E138-F153 HydrophobicContact CB-CG 4.28Å; E138-F153 HydrophobicContact CB-CZ 3.73Å; E138-F153 HydrophobicContact CG-CB 4.12Å; E138-F153 HydrophobicContact CG-CD1 3.38Å; E138-F153 HydrophobicContact CG-CD2 3.96Å; E138-F153 HydrophobicContact CG-CE1 3.67Å; E138-F153 HydrophobicContact CG-CE2 4.22Å; E138-F153 HydrophobicContact CG-CG 3.54Å; E138-F153 HydrophobicContact CG-CZ 4.08Å; V141-F153 HydrophobicContact CB-CD2 4.48Å; V141-F153 HydrophobicContact CB-CE2 3.93Å; V141-F153 HydrophobicContact CG1-CD2 4.38Å; V141-F153 HydrophobicContact CG1-CE2 4.12Å; V141-F153 HydrophobicContact CG2-CE2 4.17Å; S149-F153 WeakPolarHBondContact O-CA 3.42Å; S149-F153 WeakPolarHBondContact O-CB 3.41Å; S149-F153 PolarHBondContact O-N 2.93Å
154	T	94.5	Very high	93.1	Very high	55 Å²	55	87.2 Å²	87.2	34%	0.337	41%	0.408	S	S	.	.			trans	-75.9	154.9	168.7	79.6	0	0	0	0	110.3	Y152 K156 T157 T158	Y152-T154 VanDerWaalsContact C-N 3.25Å; Y152-T154 PolarHBondContact O-N 3.46Å; Y152-T154 VanDerWaalsContact O-N 3.14Å; T154-K156 PolarHBondContact O-N 3.46Å; T154-K156 VanDerWaalsContact O-N 3.15Å; T154-T157 PolarHBondContact O-N 3.37Å; T154-T157 PolarHBondContact OG1-N 3.2Å; T154-T157 PolarHBondContact OG1-OG1 3.32Å; T154-T158 PolarHBondContact O-N 3.14Å; T154-T158 PolarHBondContact O-OG1 2.9Å
155	R	94.2	Very high	93.7	Very high	142 Å²	142	82.8 Å²	82.8	54%	0.536	39%	0.39	S	S	.	.	H	α-helix	trans	-54.9	-36.3	178.7	-63	179.7	179.8	154.1	1.5	113.2	S66 I71 R159	S66-R155 WeakPolarHBondContact O-CD 3.3Å; S66-R155 WeakPolarHBondContact O-CG 3.38Å; S66-R155 PolarHBondContact O-NE 3.39Å; S66-R155 PolarHBondContact OG-NH2 2.87Å; I71-R155 HydrophobicContact CD1-CB 4.15Å; I71-R155 HydrophobicContact CD1-CG 4.03Å; R155-R159 VanDerWaalsContact O-CG 3.3Å; R155-R159 WeakPolarHBondContact O-CG 3.23Å; R155-R159 PolarHBondContact O-N 2.87Å
156	K	95.6	Very high	94.2	Very high	151 Å²	151	80.4 Å²	80.4	66%	0.657	38%	0.381	S	S	*	.	H	α-helix	trans	-68.6	-50.3	179.5	-175.6	-179.4	178.1	-177.4	0	110.5	T154 T158 R159 Q160	T154-K156 PolarHBondContact O-N 3.46Å; T154-K156 VanDerWaalsContact O-N 3.15Å; K156-T158 VanDerWaalsContact C-N 3.33Å; K156-T158 PolarHBondContact O-N 2.97Å; K156-R159 PolarHBondContact O-N 2.93Å; K156-Q160 WeakPolarHBondContact O-CG 3.45Å; K156-Q160 PolarHBondContact O-N 3.37Å
157	T	96.5	Very high	94.8	Very high	61 Å²	61	80.1 Å²	80.1	37%	0.374	39%	0.387	S	S	.	.	H	α-helix	trans	-61.8	-41.5	178.7	-47.9	0	0	0	0	111.5	Y152 T154 R159 Q160 L161	Y152-T157 VanDerWaalsContact O-CB 3.3Å; Y152-T157 WeakPolarHBondContact O-CB 3.47Å; Y152-T157 WeakPolarHBondContact O-CG2 3.38Å; T154-T157 PolarHBondContact O-N 3.37Å; T154-T157 PolarHBondContact OG1-N 3.2Å; T154-T157 PolarHBondContact OG1-OG1 3.32Å; T157-R159 VanDerWaalsContact C-N 3.34Å; T157-R159 PolarHBondContact O-N 3.45Å; T157-Q160 PolarHBondContact O-N 3.48Å; T157-L161 WeakPolarHBondContact O-CB 3.37Å; T157-L161 PolarHBondContact O-N 2.84Å
158	T	97.6	Very high	95.1	Very high	1 Å²	1	81.4 Å²	81.4	1%	0.006	39%	0.386	C	S	.	.	H	α-helix	trans	-60.7	-42.3	176.1	-52.9	0	0	0	0	111.9	S68 I71 L72 T154 K156 L161 I162	S68-T158 WeakPolarHBondContact CB-OG1 3.36Å; S68-T158 WeakPolarHBondContact OG-CG2 3.35Å; S68-T158 PolarHBondContact OG-OG1 3.31Å; I71-T158 HydrophobicContact CB-CG2 4.26Å; I71-T158 HydrophobicContact CG2-CG2 4.22Å; L72-T158 HydrophobicContact CD1-CG2 4.4Å; L72-T158 HydrophobicContact CD2-CG2 4.08Å; L72-T158 HydrophobicContact CG-CG2 3.81Å; T154-T158 PolarHBondContact O-N 3.14Å; T154-T158 PolarHBondContact O-OG1 2.9Å; K156-T158 VanDerWaalsContact C-N 3.33Å; K156-T158 PolarHBondContact O-N 2.97Å; T158-L161 PolarHBondContact O-N 3.18Å; T158-I162 HydrophobicContact CG2-CD1 4.14Å; T158-I162 VanDerWaalsContact O-CG1 3.25Å; T158-I162 WeakPolarHBondContact O-CG1 3.41Å; T158-I162 PolarHBondContact O-N 2.98Å
159	R	97.4	Very high	95.5	Very high	165 Å²	165	77.6 Å²	77.6	62%	0.623	37%	0.366	S	S	*	.	H	α-helix	trans	-66.3	-38.9	176.5	-73.4	173.4	179.3	-179.8	-2.1	112.6	I71 R155 K156 T157 I162 A163	I71-R159 HydrophobicContact CG2-CG 4.36Å; R155-R159 VanDerWaalsContact O-CG 3.3Å; R155-R159 WeakPolarHBondContact O-CG 3.23Å; R155-R159 PolarHBondContact O-N 2.87Å; K156-R159 PolarHBondContact O-N 2.93Å; T157-R159 VanDerWaalsContact C-N 3.34Å; T157-R159 PolarHBondContact O-N 3.45Å; R159-I162 PolarHBondContact O-N 2.98Å; R159-A163 PolarHBondContact O-N 3.36Å
160	Q	98.1	Very high	95.8	Very high	106 Å²	106	81.8 Å²	81.8	50%	0.495	38%	0.383	S	S	.	.	H	α-helix	trans	-64.3	-45.3	174.7	-71.9	173.9	-32.9	0	0	111.2	K156 T157 I162 A163 S164	K156-Q160 WeakPolarHBondContact O-CG 3.45Å; K156-Q160 PolarHBondContact O-N 3.37Å; T157-Q160 PolarHBondContact O-N 3.48Å; Q160-I162 VanDerWaalsContact C-N 3.34Å; Q160-I162 PolarHBondContact O-N 3.36Å; Q160-A163 PolarHBondContact O-N 3.09Å; Q160-S164 PolarHBondContact O-N 2.9Å; Q160-S164 PolarHBondContact O-OG 2.94Å; Q160-S164 VanDerWaalsContact O-OG 3.13Å
161	L	98	Very high	96	Very high	66 Å²	66	80.8 Å²	80.8	35%	0.346	38%	0.383	S	S	.	.	H	α-helix	trans	-56.6	-47.1	174.8	174.9	62.8	0	0	0	111.7	A134 T157 T158 A163 S164 I165	A134-L161 HydrophobicContact CB-CD2 4.04Å; T157-L161 WeakPolarHBondContact O-CB 3.37Å; T157-L161 PolarHBondContact O-N 2.84Å; T158-L161 PolarHBondContact O-N 3.18Å; L161-A163 PolarHBondContact O-N 3.35Å; L161-S164 PolarHBondContact O-N 3.36Å; L161-I165 HydrophobicContact CD1-CD1 4.06Å; L161-I165 HydrophobicContact CD1-CG1 4.33Å; L161-I165 HydrophobicContact CG-CD1 3.98Å; L161-I165 WeakPolarHBondContact O-CG1 3.34Å; L161-I165 PolarHBondContact O-N 3.19Å
162	I	98.5	Very high	96.1	Very high	16 Å²	16	74.2 Å²	74.2	8%	0.082	36%	0.36	C	S	.	.	H	α-helix	trans	-58.6	-48.3	176	-72	166.9	0	0	0	110.8	I71 L72 V75 L131 T158 R159 Q160 S164 I165 C166	I71-I162 HydrophobicContact CG2-CD1 3.66Å; L72-I162 HydrophobicContact CD2-CD1 3.95Å; L72-I162 HydrophobicContact CD2-CG1 3.68Å; V75-I162 HydrophobicContact CB-CG2 4.29Å; V75-I162 HydrophobicContact CG1-CG2 4.01Å; V75-I162 HydrophobicContact CG2-CD1 4.09Å; V75-I162 HydrophobicContact CG2-CG2 3.95Å; L131-I162 HydrophobicContact CD2-CG1 3.9Å; T158-I162 HydrophobicContact CG2-CD1 4.14Å; T158-I162 VanDerWaalsContact O-CG1 3.25Å; T158-I162 WeakPolarHBondContact O-CG1 3.41Å; T158-I162 PolarHBondContact O-N 2.98Å; R159-I162 PolarHBondContact O-N 2.98Å; Q160-I162 VanDerWaalsContact C-N 3.34Å; Q160-I162 PolarHBondContact O-N 3.36Å; I162-S164 VanDerWaalsContact C-N 3.3Å; I162-S164 PolarHBondContact O-N 2.97Å; I162-I165 PolarHBondContact O-N 3.43Å; I162-C166 PolarHBondContact O-N 2.79Å; I162-C166 PolarHBondContact O-SG 3.45Å; I162-C166 VanDerWaalsContact O-SG 3.34Å
163	A	98.3	Very high	96.2	Very high	48 Å²	48	68.1 Å²	68.1	40%	0.397	34%	0.336	S	S	.	.	H	α-helix	trans	-59.3	-43	179.1	0	0	0	0	0	111.4	R159 Q160 L161 C166 I167	R159-A163 PolarHBondContact O-N 3.36Å; Q160-A163 PolarHBondContact O-N 3.09Å; L161-A163 PolarHBondContact O-N 3.35Å; A163-C166 PolarHBondContact O-N 3.44Å; A163-I167 WeakPolarHBondContact O-CB 3.28Å; A163-I167 WeakPolarHBondContact O-CD1 3.21Å; A163-I167 VanDerWaalsContact O-CG1 3.25Å; A163-I167 WeakPolarHBondContact O-CG1 3.11Å; A163-I167 PolarHBondContact O-N 3.4Å
164	S	98.3	Very high	96.2	Very high	61 Å²	61	70.7 Å²	70.7	43%	0.427	35%	0.35	S	S	.	.	H	α-helix	trans	-61.2	-45.8	174.5	-60.2	0	0	0	0	112.4	Q160 L161 I162 C166 I167 I168	Q160-S164 PolarHBondContact O-N 2.9Å; Q160-S164 PolarHBondContact O-OG 2.94Å; Q160-S164 VanDerWaalsContact O-OG 3.13Å; L161-S164 PolarHBondContact O-N 3.36Å; I162-S164 VanDerWaalsContact C-N 3.3Å; I162-S164 PolarHBondContact O-N 2.97Å; S164-C166 PolarHBondContact O-N 2.85Å; S164-I167 PolarHBondContact O-N 3.06Å; S164-I168 WeakPolarHBondContact O-CB 3.19Å; S164-I168 WeakPolarHBondContact O-CD1 3.5Å; S164-I168 WeakPolarHBondContact O-CG1 3.34Å; S164-I168 PolarHBondContact O-N 2.75Å
165	I	98	Very high	96.1	Very high	19 Å²	19	69.6 Å²	69.6	10%	0.097	34%	0.344	C	S	.	.	H	α-helix	trans	-58.8	-47.2	176.8	-71	167.2	0	0	0	110.5	W130 L131 A134 L161 I162 A169	W130-I165 HydrophobicContact CB-CD1 4.33Å; W130-I165 HydrophobicContact CB-CG1 4.31Å; W130-I165 HydrophobicContact CB-CG2 3.75Å; L131-I165 HydrophobicContact CD2-CD1 4.03Å; A134-I165 HydrophobicContact CB-CD1 4.34Å; L161-I165 HydrophobicContact CD1-CD1 4.06Å; L161-I165 HydrophobicContact CD1-CG1 4.33Å; L161-I165 HydrophobicContact CG-CD1 3.98Å; L161-I165 WeakPolarHBondContact O-CG1 3.34Å; L161-I165 PolarHBondContact O-N 3.19Å; I162-I165 PolarHBondContact O-N 3.43Å; I165-A169 VanDerWaalsContact O-CB 3.24Å; I165-A169 WeakPolarHBondContact O-CB 3.44Å; I165-A169 PolarHBondContact O-N 3.21Å
166	C	98.1	Very high	95.8	Very high	29 Å²	29	64 Å²	64	20%	0.196	32%	0.323	C	S	.	.	H	α-helix	trans	-60.3	-52.2	178.1	-67.4	0	0	0	0	111.3	I127 I162 A163 S164 I168 A169 F170	I127-C166 HydrophobicContact CD1-CB 4.37Å; I162-C166 PolarHBondContact O-N 2.79Å; I162-C166 PolarHBondContact O-SG 3.45Å; I162-C166 VanDerWaalsContact O-SG 3.34Å; A163-C166 PolarHBondContact O-N 3.44Å; S164-C166 PolarHBondContact O-N 2.85Å; C166-I168 PolarHBondContact O-N 3.26Å; C166-A169 PolarHBondContact O-N 2.87Å; C166-F170 WeakPolarHBondContact O-CD2 3.35Å; C166-F170 PolarHBondContact O-N 2.81Å
167	I	98	Very high	95.7	Very high	99 Å²	99	61.3 Å²	61.3	51%	0.508	31%	0.312	S	S	.	.	H	α-helix	trans	-58.2	-47.4	-178.8	-69.1	165.1	0	0	0	111	A163 S164 A169 F170 I171	A163-I167 WeakPolarHBondContact O-CB 3.28Å; A163-I167 WeakPolarHBondContact O-CD1 3.21Å; A163-I167 VanDerWaalsContact O-CG1 3.25Å; A163-I167 WeakPolarHBondContact O-CG1 3.11Å; A163-I167 PolarHBondContact O-N 3.4Å; S164-I167 PolarHBondContact O-N 3.06Å; I167-A169 PolarHBondContact O-N 2.94Å; I167-F170 PolarHBondContact O-N 3.23Å; I167-I171 HydrophobicContact CG2-CD1 3.64Å; I167-I171 HydrophobicContact CG2-CG1 4.42Å; I167-I171 VanDerWaalsContact O-CG1 3.32Å; I167-I171 WeakPolarHBondContact O-CG1 3.2Å; I167-I171 PolarHBondContact O-N 3.32Å
168	I	96.1	Very high	95.4	Very high	107 Å²	107	60.6 Å²	60.6	55%	0.549	31%	0.312	S	S	.	.	H	α-helix	trans	-62	-44.9	178.4	-68.2	166.7	0	0	0	110.3	S164 C166 F170 I171 F172	S164-I168 WeakPolarHBondContact O-CB 3.19Å; S164-I168 WeakPolarHBondContact O-CD1 3.5Å; S164-I168 WeakPolarHBondContact O-CG1 3.34Å; S164-I168 PolarHBondContact O-N 2.75Å; C166-I168 PolarHBondContact O-N 3.26Å; I168-F170 PolarHBondContact O-N 3.44Å; I168-I171 PolarHBondContact O-N 3.19Å; I168-F172 WeakPolarHBondContact O-CB 3.23Å; I168-F172 PolarHBondContact O-N 2.91Å
169	A	96	Very high	94.9	Very high	1 Å²	1	61.5 Å²	61.5	1%	0.008	32%	0.316	C	S	.	.	H	α-helix	trans	-63.5	-39.8	179.5	0	0	0	0	0	112.5	N126 I127 I165 C166 I167 N173	N126-A169 HydrophobicContact CB-CB 4.18Å; I127-A169 HydrophobicContact CD1-CB 4.3Å; I127-A169 HydrophobicContact CG1-CB 3.49Å; I127-A169 VanDerWaalsContact CG1-CB 3.49Å; I165-A169 VanDerWaalsContact O-CB 3.24Å; I165-A169 WeakPolarHBondContact O-CB 3.44Å; I165-A169 PolarHBondContact O-N 3.21Å; C166-A169 PolarHBondContact O-N 2.87Å; I167-A169 PolarHBondContact O-N 2.94Å; A169-N173 WeakPolarHBondContact O-CB 3.32Å; A169-N173 PolarHBondContact O-N 3.21Å; A169-N173 PolarHBondContact O-ND2 2.94Å
170	F	95.1	Very high	94.3	Very high	101 Å²	101	56.4 Å²	56.4	44%	0.443	30%	0.3	S	S	.	.	H	α-helix	trans	-62.8	-57.3	173.9	-81.8	-70.6	0	0	0	111	M123 I127 C166 I167 I168 F172 N173 I174	M123-F170 HydrophobicContact CB-CD1 4.42Å; M123-F170 HydrophobicContact CB-CE1 4.37Å; M123-F170 HydrophobicContact CE-CD1 4.15Å; M123-F170 HydrophobicContact CG-CD1 4.11Å; M123-F170 HydrophobicContact CG-CE1 4.43Å; M123-F170 HydrophobicContact SD-CD1 3.37Å; M123-F170 WeakPolarHBondContact SD-CD1 3.46Å; M123-F170 HydrophobicContact SD-CE1 3.6Å; M123-F170 VanDerWaalsContact SD-CE1 3.6Å; M123-F170 HydrophobicContact SD-CG 4.49Å; I127-F170 HydrophobicContact CD1-CE2 4.19Å; C166-F170 WeakPolarHBondContact O-CD2 3.35Å; C166-F170 PolarHBondContact O-N 2.81Å; I167-F170 PolarHBondContact O-N 3.23Å; I168-F170 PolarHBondContact O-N 3.44Å; F170-F172 VanDerWaalsContact C-N 3.32Å; F170-F172 PolarHBondContact O-N 3.29Å; F170-N173 PolarHBondContact O-N 3.4Å; F170-N173 VanDerWaalsContact O-N 3.08Å; F170-I174 WeakPolarHBondContact O-CG1 3.38Å; F170-I174 PolarHBondContact O-N 3.47Å
171	I	94.4	Very high	93.7	Very high	108 Å²	108	59.7 Å²	59.7	55%	0.554	31%	0.308	S	S	*	.	H	α-helix	trans	-56.6	-47.6	-177.1	-67.7	171.1	0	0	0	111	I167 I168 N173 I174	I167-I171 HydrophobicContact CG2-CD1 3.64Å; I167-I171 HydrophobicContact CG2-CG1 4.42Å; I167-I171 VanDerWaalsContact O-CG1 3.32Å; I167-I171 WeakPolarHBondContact O-CG1 3.2Å; I167-I171 PolarHBondContact O-N 3.32Å; I168-I171 PolarHBondContact O-N 3.19Å; I171-N173 PolarHBondContact O-N 2.79Å; I171-I174 PolarHBondContact O-N 2.8Å
172	F	91.9	Very high	93.1	Very high	52 Å²	52	57.6 Å²	57.6	23%	0.228	30%	0.298	C	S	.	.	H	α-helix	trans	-64.3	-24.7	-177	-168.4	-99	0	0	0	112.8	I168 F170 Y209 R213 V217	I168-F172 WeakPolarHBondContact O-CB 3.23Å; I168-F172 PolarHBondContact O-N 2.91Å; F170-F172 VanDerWaalsContact C-N 3.32Å; F170-F172 PolarHBondContact O-N 3.29Å; F172-Y209 HydrophobicContact CE1-CE2 4.35Å; F172-Y209 HydrophobicContact CE2-CE2 4.36Å; F172-Y209 HydrophobicContact CZ-CE2 4.2Å; F172-Y209 WeakPolarHBondContact O-CE2 3.39Å; F172-Y209 PolarHBondContact O-OH 3.3Å; F172-R213 HydrophobicContact CE1-CB 3.69Å; F172-R213 HydrophobicContact CE1-CG 3.92Å; F172-R213 HydrophobicContact CZ-CB 4.02Å; F172-V217 HydrophobicContact CD1-CG2 3.76Å; F172-V217 HydrophobicContact CE1-CG2 3.49Å; F172-V217 VanDerWaalsContact CE1-CG2 3.49Å; F172-V217 HydrophobicContact CZ-CG2 4.49Å
173	N	92.6	Very high	92.3	Very high	0 Å²	0	58.6 Å²	58.6	0%	0	31%	0.306	C	S	.	.	H	α-helix	trans	-97.6	-5.4	-179.9	-81	-78.7	0	0	0	114.4	N122 M123 N126 A169 F170 I171 P175 Y176 R213	N122-N173 WeakPolarHBondContact CB-OD1 3.44Å; N122-N173 PolarHBondContact O-ND2 3.43Å; N122-N173 PolarHBondContact O-OD1 3.09Å; M123-N173 HydrophobicContact CB-CB 4.49Å; M123-N173 HydrophobicContact CE-CB 3.87Å; M123-N173 HydrophobicContact CG-CB 3.39Å; N126-N173 PolarHBondContact ND2-ND2 3.24Å; A169-N173 WeakPolarHBondContact O-CB 3.32Å; A169-N173 PolarHBondContact O-N 3.21Å; A169-N173 PolarHBondContact O-ND2 2.94Å; F170-N173 PolarHBondContact O-N 3.4Å; F170-N173 VanDerWaalsContact O-N 3.08Å; I171-N173 PolarHBondContact O-N 2.79Å; N173-P175 VanDerWaalsContact C-N 3.27Å; N173-Y176 HydrophobicContact CB-CD2 4.33Å; N173-Y176 WeakPolarHBondContact O-CB 3.43Å; N173-Y176 WeakPolarHBondContact O-CD2 3.22Å; N173-Y176 PolarHBondContact O-N 2.96Å; N173-R213 PolarHBondContact OD1-NH1 3.03Å
174	I	92.6	Very high	91.6	Very high	96 Å²	96	60.6 Å²	60.6	49%	0.492	31%	0.309	S	S	.	.	G	3₁₀ helix	trans	-50.2	-40.3	177.9	-70	174.2	0	0	0	113.3	F170 I171 Y176 F177	F170-I174 WeakPolarHBondContact O-CG1 3.38Å; F170-I174 PolarHBondContact O-N 3.47Å; I171-I174 PolarHBondContact O-N 2.8Å; I174-Y176 PolarHBondContact O-N 3.18Å; I174-F177 WeakPolarHBondContact O-CD2 3.2Å; I174-F177 PolarHBondContact O-N 2.86Å; I174-F177 VanDerWaalsContact O-N 3.15Å
175	P	92.2	Very high	90.7	Very high	32 Å²	32	63.3 Å²	63.3	21%	0.208	31%	0.313	C	S	.	.	G	3₁₀ helix	trans	-56.5	-20.5	-179.9	-28.6	37.7	0	0	0	115	N173 F177 A178 F200 Y209	N173-P175 VanDerWaalsContact C-N 3.27Å; P175-F177 VanDerWaalsContact C-N 3.26Å; P175-F177 PolarHBondContact O-N 3.15Å; P175-A178 PolarHBondContact O-N 3.48Å; P175-A178 VanDerWaalsContact O-N 3.07Å; P175-F200 HydrophobicContact CB-CE1 4.02Å; P175-F200 HydrophobicContact CB-CZ 4.14Å; P175-Y209 HydrophobicContact CB-CD1 4.42Å; P175-Y209 HydrophobicContact CB-CE1 3.91Å; P175-Y209 HydrophobicContact CG-CD2 4.45Å; P175-Y209 HydrophobicContact CG-CE1 4.23Å; P175-Y209 HydrophobicContact CG-CE2 3.92Å
176	Y	89.3	Confident	89.8	Confident	25 Å²	25	70.8 Å²	70.8	10%	0.098	34%	0.342	C	S	.	.	G	3₁₀ helix	trans	-60.8	-32.1	178	-84.8	-83.4	0	0	0	113.9	T118 N122 N173 I174 A178 I179 R213	T118-Y176 HydrophobicContact CG2-CD1 4.09Å; N122-Y176 HydrophobicContact CB-CD2 4.47Å; N122-Y176 HydrophobicContact CB-CE2 4.43Å; N173-Y176 HydrophobicContact CB-CD2 4.33Å; N173-Y176 WeakPolarHBondContact O-CB 3.43Å; N173-Y176 WeakPolarHBondContact O-CD2 3.22Å; N173-Y176 PolarHBondContact O-N 2.96Å; I174-Y176 PolarHBondContact O-N 3.18Å; Y176-A178 PolarHBondContact O-N 2.9Å; Y176-A178 VanDerWaalsContact O-N 3.16Å; Y176-I179 HydrophobicContact CD1-CD1 3.21Å; Y176-I179 HydrophobicContact CE1-CD1 3.58Å; Y176-I179 HydrophobicContact CG-CD1 3.86Å; Y176-I179 PolarHBondContact O-N 3.3Å; Y176-R213 WeakPolarHBondContact OH-CD 3.48Å; Y176-R213 PolarHBondContact OH-NE 3.23Å
177	F	92.1	Very high	88.7	Confident	95 Å²	95	71.9 Å²	71.9	42%	0.417	35%	0.348	S	S	.	.	G	3₁₀ helix	trans	-66	-16.4	177.1	-66.4	-75.2	0	0	0	113.2	Y115 P119 M123 I174 P175	Y115-F177 WeakPolarHBondContact O-CE1 3.37Å; P119-F177 HydrophobicContact CB-CD1 3.84Å; P119-F177 HydrophobicContact CB-CD2 4.19Å; P119-F177 HydrophobicContact CB-CE1 3.46Å; P119-F177 VanDerWaalsContact CB-CE1 3.46Å; P119-F177 HydrophobicContact CB-CE2 3.86Å; P119-F177 HydrophobicContact CB-CG 4.19Å; P119-F177 HydrophobicContact CB-CZ 3.47Å; P119-F177 VanDerWaalsContact CB-CZ 3.47Å; P119-F177 HydrophobicContact CG-CD1 3.57Å; P119-F177 HydrophobicContact CG-CE1 3.59Å; P119-F177 HydrophobicContact CG-CG 4.09Å; P119-F177 HydrophobicContact CG-CZ 4.13Å; M123-F177 HydrophobicContact CE-CD2 4.46Å; M123-F177 HydrophobicContact CE-CE2 3.46Å; M123-F177 VanDerWaalsContact CE-CE2 3.46Å; M123-F177 HydrophobicContact CE-CZ 3.98Å; I174-F177 WeakPolarHBondContact O-CD2 3.2Å; I174-F177 PolarHBondContact O-N 2.86Å; I174-F177 VanDerWaalsContact O-N 3.15Å; P175-F177 VanDerWaalsContact C-N 3.26Å; P175-F177 PolarHBondContact O-N 3.15Å
178	A	91.1	Very high	87.8	Confident	46 Å²	46	74.8 Å²	74.8	38%	0.38	36%	0.364	S	S	.	.	G	3₁₀ helix	trans	-107.7	6.4	-175.4	0	0	0	0	0	113.8	P175 Y176 T198 F200	P175-A178 PolarHBondContact O-N 3.48Å; P175-A178 VanDerWaalsContact O-N 3.07Å; Y176-A178 PolarHBondContact O-N 2.9Å; Y176-A178 VanDerWaalsContact O-N 3.16Å; A178-T198 WeakPolarHBondContact O-CB 3.44Å; A178-T198 WeakPolarHBondContact O-CG2 3.32Å; A178-T198 PolarHBondContact O-OG1 2.89Å; A178-F200 HydrophobicContact CB-CD1 4.14Å
179	I	86.6	Confident	86.7	Confident	19 Å²	19	72.7 Å²	72.7	10%	0.097	37%	0.369	C	S	.	.	S	Bend	trans	-76.3	-43	-174.7	-62.3	170.1	0	0	0	111.8	Y176 L197 T198 S201 Y206	Y176-I179 HydrophobicContact CD1-CD1 3.21Å; Y176-I179 HydrophobicContact CE1-CD1 3.58Å; Y176-I179 HydrophobicContact CG-CD1 3.86Å; Y176-I179 PolarHBondContact O-N 3.3Å; I179-L197 HydrophobicContact CG2-CD2 4.25Å; I179-T198 PolarHBondContact O-N 2.84Å; I179-T198 PolarHBondContact O-OG1 3.26Å; I179-S201 WeakPolarHBondContact O-CB 3.25Å; I179-Y206 HydrophobicContact CD1-CE2 3.88Å; I179-Y206 WeakPolarHBondContact CD1-OH 3.39Å; I179-Y206 HydrophobicContact CG1-CE2 3.76Å
180	Q	85.9	Confident	85.5	Confident	59 Å²	59	73.7 Å²	73.7	28%	0.276	38%	0.375	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.4	144.4	-172.1	-74.6	176.1	-30.7	0	0	111.5	I114 D196 L197	I114-Q180 HydrophobicContact CD1-CB 4.41Å; I114-Q180 VanDerWaalsContact CG1-OE1 3.28Å; I114-Q180 HydrophobicContact CG2-CB 3.76Å; Q180-D196 WeakPolarHBondContact CA-O 3.42Å; Q180-L197 HydrophobicContact CG-CD2 4.13Å
181	R	85.2	Confident	84.6	Confident	175 Å²	175	70.2 Å²	70.2	66%	0.66	36%	0.361	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-119.7	124.5	170	179.3	179.7	-77.3	177.1	-5.8	108.3	D196 T198	R181-D196 PolarHBondContact N-O 2.9Å; R181-D196 PolarHBondContact O-N 3.12Å; R181-T198 HydrophobicContact CB-CG2 4.09Å
182	V	84.7	Confident	83.6	Confident	22 Å²	22	66.9 Å²	66.9	13%	0.133	34%	0.343	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-91.3	131.6	172.5	-179.8	0	0	0	0	108.9	M111 I114 Y115 L193	M111-V182 HydrophobicContact CG-CG1 4.12Å; I114-V182 HydrophobicContact CD1-CG2 3.59Å; Y115-V182 HydrophobicContact CE2-CB 4.18Å; Y115-V182 HydrophobicContact CE2-CG2 3.85Å; Y115-V182 PolarHBondContact OH-N 3.36Å; Y115-V182 VanDerWaalsContact OH-N 3.08Å; V182-L193 HydrophobicContact CG1-CD1 3.44Å; V182-L193 VanDerWaalsContact CG1-CD1 3.44Å; V182-L193 HydrophobicContact CG1-CD2 4.36Å; V182-L193 HydrophobicContact CG1-CG 3.72Å
183	S	82.8	Confident	82.9	Confident	36 Å²	36	64.5 Å²	64.5	25%	0.252	33%	0.333	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-124.1	137.4	167.8	64.8	0	0	0	0	109.9	H194	S183-H194 PolarHBondContact N-O 3.18Å; S183-H194 PolarHBondContact O-N 3.08Å
184	L	81.9	Confident	82.2	Confident	90 Å²	90	66.5 Å²	66.5	47%	0.471	34%	0.342	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.8	125.8	173.6	-66.2	176.2	0	0	0	107.9	I107 L191 L193	I107-L184 HydrophobicContact CG2-CD2 4.12Å; L184-L191 HydrophobicContact CB-CD1 3.98Å; L184-L191 HydrophobicContact CD2-CD1 4.31Å; L184-L193 HydrophobicContact CD2-CB 4.18Å; L184-L193 HydrophobicContact CD2-CD1 4.2Å; L184-L193 HydrophobicContact CD2-CG 4.43Å
185	K	80	Confident	81.7	Confident	118 Å²	118	63.1 Å²	63.1	51%	0.513	33%	0.327	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.6	131.1	176.7	-69.1	-175.3	179.7	176.5	0	109.3	V187 Q192	K185-V187 HydrophobicContact CB-CG2 4.29Å; K185-V187 PolarHBondContact O-N 3.44Å; K185-Q192 PolarHBondContact N-O 3.05Å; K185-Q192 WeakPolarHBondContact O-CA 3.42Å; K185-Q192 PolarHBondContact O-N 3.08Å
186	Y	79	Confident	81	Confident	176 Å²	176	64.3 Å²	64.3	69%	0.69	33%	0.331	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-80.2	117.6	165.7	-80.8	-89.4	0	0	0	108.8	V190 L191	Y186-V190 CarbonylContact C-O 3.59Å; Y186-V190 VanDerWaalsContact CA-O 3.3Å; Y186-V190 WeakPolarHBondContact CA-O 3.39Å; Y186-L191 HydrophobicContact CD1-CB 4.25Å; Y186-L191 HydrophobicContact CD2-CD1 4.02Å; Y186-L191 HydrophobicContact CE1-CB 3.8Å; Y186-L191 HydrophobicContact CE1-CD1 4.39Å; Y186-L191 HydrophobicContact CE2-CD1 3.65Å
187	V	75.5	Confident	80.7	Confident	53 Å²	53	67 Å²	67	32%	0.321	35%	0.347	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-123.4	124.1	175.1	-177.9	0	0	0	0	106.6	K185 G189 V190 Q192	K185-V187 HydrophobicContact CB-CG2 4.29Å; K185-V187 PolarHBondContact O-N 3.44Å; V187-G189 VanDerWaalsContact C-N 3.25Å; V187-G189 PolarHBondContact O-N 3.47Å; V187-V190 PolarHBondContact N-O 3.39Å; V187-V190 WeakPolarHBondContact O-CA 3.46Å; V187-V190 WeakPolarHBondContact O-CB 3.28Å; V187-V190 PolarHBondContact O-N 3.39Å; V187-Q192 HydrophobicContact CB-CG 4.3Å; V187-Q192 HydrophobicContact CG2-CG 4.48Å
188	D	78.5	Confident	80.4	Confident	159 Å²	159	63.8 Å²	63.8	85%	0.85	34%	0.335	S	S	*	.	T	Hydrogen-bonded Turn	trans	53	38.2	179.1	-54.5	-35.5	0	0	0	114.6	V190	D188-V190 PolarHBondContact O-N 3.14Å
189	G	74	Confident	80.2	Confident	64 Å²	64	66.9 Å²	66.9	66%	0.66	35%	0.354	S	S	*	.	T	Hydrogen-bonded Turn	trans	77.5	-3.5	-178.5	0	0	0	0	0	114.6	V187	V187-G189 VanDerWaalsContact C-N 3.25Å; V187-G189 PolarHBondContact O-N 3.47Å
190	V	70.8	Confident	80.3	Confident	21 Å²	21	69.5 Å²	69.5	13%	0.127	37%	0.365	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-97.6	131.5	177.3	169.3	0	0	0	0	110.3	D5 I6 Y186 V187 D188 Q192	D5-V190 HydrophobicContact CB-CG2 4.14Å; D5-V190 WeakPolarHBondContact O-CG1 3.31Å; I6-V190 VanDerWaalsContact CA-CG1 3.46Å; I6-V190 HydrophobicContact CB-CG1 4.43Å; I6-V190 HydrophobicContact CG1-CG1 4.22Å; Y186-V190 CarbonylContact C-O 3.59Å; Y186-V190 VanDerWaalsContact CA-O 3.3Å; Y186-V190 WeakPolarHBondContact CA-O 3.39Å; V187-V190 PolarHBondContact N-O 3.39Å; V187-V190 WeakPolarHBondContact O-CA 3.46Å; V187-V190 WeakPolarHBondContact O-CB 3.28Å; V187-V190 PolarHBondContact O-N 3.39Å; D188-V190 PolarHBondContact O-N 3.14Å; V190-Q192 HydrophobicContact CG1-CG 3.9Å; V190-Q192 PolarHBondContact O-N 3.03Å
191	L	74.7	Confident	80.1	Confident	29 Å²	29	67.1 Å²	67.1	15%	0.152	35%	0.354	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-72	108.7	167.7	178.3	65.6	0	0	0	109.6	I6 I107 L184 Y186	I6-L191 WeakPolarHBondContact CB-O 3.32Å; I6-L191 HydrophobicContact CD1-CB 3.85Å; I6-L191 HydrophobicContact CD1-CD2 4.21Å; I6-L191 HydrophobicContact CD1-CG 4.29Å; I6-L191 WeakPolarHBondContact CD1-O 3.17Å; I6-L191 HydrophobicContact CG1-CB 4.29Å; I6-L191 WeakPolarHBondContact CG1-O 3.49Å; I6-L191 WeakPolarHBondContact CG2-O 3.5Å; I107-L191 HydrophobicContact CD1-CD2 4.02Å; I107-L191 HydrophobicContact CD1-CG 4.31Å; L184-L191 HydrophobicContact CB-CD1 3.98Å; L184-L191 HydrophobicContact CD2-CD1 4.31Å; Y186-L191 HydrophobicContact CD1-CB 4.25Å; Y186-L191 HydrophobicContact CD2-CD1 4.02Å; Y186-L191 HydrophobicContact CE1-CB 3.8Å; Y186-L191 HydrophobicContact CE1-CD1 4.39Å; Y186-L191 HydrophobicContact CE2-CD1 3.65Å
192	Q	74.5	Confident	80	Confident	37 Å²	37	67.5 Å²	67.5	17%	0.173	36%	0.356	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-102.3	137.6	175.5	-64.3	-173.5	0.7	0	0	110.8	K185 V187 V190	K185-Q192 PolarHBondContact N-O 3.05Å; K185-Q192 WeakPolarHBondContact O-CA 3.42Å; K185-Q192 PolarHBondContact O-N 3.08Å; V187-Q192 HydrophobicContact CB-CG 4.3Å; V187-Q192 HydrophobicContact CG2-CG 4.48Å; V190-Q192 HydrophobicContact CG1-CG 3.9Å; V190-Q192 PolarHBondContact O-N 3.03Å
193	L	77.6	Confident	80.2	Confident	3 Å²	3	67.8 Å²	67.8	2%	0.016	36%	0.359	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-94.1	119.9	170.1	179.4	139.7	0	0	0	109.2	L8 I107 Y110 M111 V182 L184	L8-L193 HydrophobicContact CD2-CD2 3.82Å; I107-L193 HydrophobicContact CB-CD1 4.49Å; I107-L193 HydrophobicContact CG1-CB 4.32Å; I107-L193 HydrophobicContact CG2-CD1 3.73Å; Y110-L193 HydrophobicContact CD1-CD1 3.97Å; Y110-L193 HydrophobicContact CD1-CD2 3.35Å; Y110-L193 HydrophobicContact CD1-CG 4.34Å; Y110-L193 HydrophobicContact CE1-CD2 3.37Å; Y110-L193 HydrophobicContact CG-CD2 4.31Å; M111-L193 HydrophobicContact CG-CD1 4Å; V182-L193 HydrophobicContact CG1-CD1 3.44Å; V182-L193 VanDerWaalsContact CG1-CD1 3.44Å; V182-L193 HydrophobicContact CG1-CD2 4.36Å; V182-L193 HydrophobicContact CG1-CG 3.72Å; L184-L193 HydrophobicContact CD2-CB 4.18Å; L184-L193 HydrophobicContact CD2-CD1 4.2Å; L184-L193 HydrophobicContact CD2-CG 4.43Å
194	H	77.7	Confident	80.5	Confident	42 Å²	42	71.5 Å²	71.5	19%	0.194	38%	0.38	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-109.7	120.2	174.2	-163.3	68.3	0	0	0	110	S183 D196	S183-H194 PolarHBondContact N-O 3.18Å; S183-H194 PolarHBondContact O-N 3.08Å; H194-D196 VanDerWaalsContact CD2-CG 3.48Å; H194-D196 IonicContact CD2-OD1 2.8Å; H194-D196 IonicContact CD2-OD2 3.32Å; H194-D196 PolarHBondContact CD2-OD2 2.84Å; H194-D196 IonicContact NE2-OD1 3.54Å; H194-D196 PolarHBondContact NE2-OD1 3.22Å; H194-D196 IonicContact NE2-OD2 3.14Å
195	S	80.8	Confident	80.8	Confident	24 Å²	24	75.9 Å²	75.9	17%	0.168	39%	0.392	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-103.8	109.6	177.4	172.9	0	0	0	0	110
196	D	78.6	Confident	81.2	Confident	57 Å²	57	71.4 Å²	71.4	31%	0.305	37%	0.372	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-101.8	141.6	176	-79.1	-47.8	0	0	0	111.8	Q180 R181 H194	Q180-D196 WeakPolarHBondContact CA-O 3.42Å; R181-D196 PolarHBondContact N-O 2.9Å; R181-D196 PolarHBondContact O-N 3.12Å; H194-D196 VanDerWaalsContact CD2-CG 3.48Å; H194-D196 IonicContact CD2-OD1 2.8Å; H194-D196 IonicContact CD2-OD2 3.32Å; H194-D196 PolarHBondContact CD2-OD2 2.84Å; H194-D196 IonicContact NE2-OD1 3.54Å; H194-D196 PolarHBondContact NE2-OD1 3.22Å; H194-D196 IonicContact NE2-OD2 3.14Å
197	L	82.7	Confident	81.6	Confident	83 Å²	83	64.5 Å²	64.5	44%	0.435	35%	0.351	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-69.1	130.7	163	-64.5	176.4	0	0	0	109.2	I179 Q180 R202	I179-L197 HydrophobicContact CG2-CD2 4.25Å; Q180-L197 HydrophobicContact CG-CD2 4.13Å; L197-R202 HydrophobicContact CB-CG 4.47Å
198	T	86	Confident	82.3	Confident	26 Å²	26	68.5 Å²	68.5	16%	0.16	37%	0.365	C	S	.	.	P	Polyproline II helix	trans	-65.9	162.1	177.4	63.1	0	0	0	0	111.9	A178 I179 R181 F200 S201 R202	A178-T198 WeakPolarHBondContact O-CB 3.44Å; A178-T198 WeakPolarHBondContact O-CG2 3.32Å; A178-T198 PolarHBondContact O-OG1 2.89Å; I179-T198 PolarHBondContact O-N 2.84Å; I179-T198 PolarHBondContact O-OG1 3.26Å; R181-T198 HydrophobicContact CB-CG2 4.09Å; T198-F200 PolarHBondContact O-N 2.95Å; T198-S201 PolarHBondContact O-N 3.45Å; T198-S201 PolarHBondContact OG1-N 3.44Å; T198-S201 VanDerWaalsContact OG1-N 3.12Å; T198-R202 PolarHBondContact O-N 2.91Å
199	S	87	Confident	82.8	Confident	111 Å²	111	62.4 Å²	62.4	78%	0.776	33%	0.33	S	S	*	.	H	α-helix	trans	-56	-36	171.2	53.7	0	0	0	0	112	R202 S203	S199-R202 PolarHBondContact O-N 3.25Å; S199-S203 PolarHBondContact O-N 2.86Å
200	F	88.3	Confident	83.4	Confident	74 Å²	74	59.8 Å²	59.8	33%	0.325	30%	0.302	S	S	.	.	H	α-helix	trans	-60.6	-48.3	172.7	175.6	-107.3	0	0	0	111.8	P175 A178 T198 R202 S203 Y206	P175-F200 HydrophobicContact CB-CE1 4.02Å; P175-F200 HydrophobicContact CB-CZ 4.14Å; A178-F200 HydrophobicContact CB-CD1 4.14Å; T198-F200 PolarHBondContact O-N 2.95Å; F200-R202 PolarHBondContact O-N 3.01Å; F200-S203 VanDerWaalsContact O-CB 3.27Å; F200-S203 WeakPolarHBondContact O-CB 3.31Å; F200-S203 PolarHBondContact O-N 3.33Å; F200-S203 PolarHBondContact O-OG 3.1Å; F200-Y206 HydrophobicContact CD1-CD2 4.21Å; F200-Y206 AromaticContact CE1-CD2 3.52Å; F200-Y206 HydrophobicContact CE1-CD2 3.52Å; F200-Y206 HydrophobicContact CE1-CE2 4.31Å; F200-Y206 HydrophobicContact CE1-CG 4.23Å; F200-Y206 AromaticContact CZ-CD2 3.96Å; F200-Y206 HydrophobicContact CZ-CD2 3.96Å; F200-Y206 WeakPolarHBondContact O-CB 3.21Å
201	S	82.8	Confident	84.3	Confident	9 Å²	9	64.4 Å²	64.4	6%	0.063	32%	0.317	C	S	.	.	H	α-helix	trans	-61.8	-26.3	179.3	-179.3	0	0	0	0	113.8	I179 T198 Y206	I179-S201 WeakPolarHBondContact O-CB 3.25Å; T198-S201 PolarHBondContact O-N 3.45Å; T198-S201 PolarHBondContact OG1-N 3.44Å; T198-S201 VanDerWaalsContact OG1-N 3.12Å; S201-Y206 VanDerWaalsContact O-CD1 3.26Å; S201-Y206 WeakPolarHBondContact O-CD1 3.46Å
202	R	82.8	Confident	85	Confident	183 Å²	183	65.9 Å²	65.9	69%	0.691	33%	0.325	S	S	*	.	H	α-helix	trans	-86.9	-10.7	176.5	-62.5	-174.8	-169.9	-168.2	1.4	113.4	L197 T198 S199 F200	L197-R202 HydrophobicContact CB-CG 4.47Å; T198-R202 PolarHBondContact O-N 2.91Å; S199-R202 PolarHBondContact O-N 3.25Å; F200-R202 PolarHBondContact O-N 3.01Å
203	S	89.1	Confident	85.6	Confident	29 Å²	29	64.3 Å²	64.3	20%	0.203	32%	0.317	C	S	.	.	S	Bend	trans	-70.3	153.2	-177.2	74	0	0	0	0	112.9	S199 F200 Y205 Y206 A207	S199-S203 PolarHBondContact O-N 2.86Å; F200-S203 VanDerWaalsContact O-CB 3.27Å; F200-S203 WeakPolarHBondContact O-CB 3.31Å; F200-S203 PolarHBondContact O-N 3.33Å; F200-S203 PolarHBondContact O-OG 3.1Å; S203-Y205 PolarHBondContact O-N 3.31Å; S203-Y206 PolarHBondContact O-N 2.88Å; S203-Y206 PolarHBondContact OG-N 3.38Å; S203-Y206 VanDerWaalsContact OG-N 3.16Å; S203-A207 PolarHBondContact O-N 3.01Å
204	T	87.8	Confident	86.1	Confident	113 Å²	113	64.8 Å²	64.8	69%	0.693	32%	0.319	S	S	*	.	H	α-helix	trans	-61.5	-31.2	170.7	50.4	0	0	0	0	112.1	A207 F208	T204-A207 WeakPolarHBondContact O-CB 3.18Å; T204-A207 PolarHBondContact O-N 3.22Å; T204-F208 PolarHBondContact O-N 2.98Å
205	Y	89.3	Confident	86.7	Confident	183 Å²	183	65.6 Å²	65.6	72%	0.718	33%	0.327	S	S	*	.	H	α-helix	trans	-60.1	-48.1	174.3	-63.2	-75	0	0	0	112.1	S203 A207 F208 Y209	S203-Y205 PolarHBondContact O-N 3.31Å; Y205-A207 VanDerWaalsContact C-N 3.32Å; Y205-A207 PolarHBondContact O-N 2.98Å; Y205-F208 PolarHBondContact O-N 3.36Å; Y205-Y209 WeakPolarHBondContact O-CB 3.39Å; Y205-Y209 PolarHBondContact O-N 3.49Å
206	Y	87.7	Confident	87.1	Confident	23 Å²	23	69 Å²	69	9%	0.09	34%	0.339	C	S	.	.	H	α-helix	trans	-67.3	-34.9	177.3	180	-102	0	0	0	111.9	I179 F200 S201 S203 Y209 S210	I179-Y206 HydrophobicContact CD1-CE2 3.88Å; I179-Y206 WeakPolarHBondContact CD1-OH 3.39Å; I179-Y206 HydrophobicContact CG1-CE2 3.76Å; F200-Y206 HydrophobicContact CD1-CD2 4.21Å; F200-Y206 AromaticContact CE1-CD2 3.52Å; F200-Y206 HydrophobicContact CE1-CD2 3.52Å; F200-Y206 HydrophobicContact CE1-CE2 4.31Å; F200-Y206 HydrophobicContact CE1-CG 4.23Å; F200-Y206 AromaticContact CZ-CD2 3.96Å; F200-Y206 HydrophobicContact CZ-CD2 3.96Å; F200-Y206 WeakPolarHBondContact O-CB 3.21Å; S201-Y206 VanDerWaalsContact O-CD1 3.26Å; S201-Y206 WeakPolarHBondContact O-CD1 3.46Å; S203-Y206 PolarHBondContact O-N 2.88Å; S203-Y206 PolarHBondContact OG-N 3.38Å; S203-Y206 VanDerWaalsContact OG-N 3.16Å; Y206-Y209 AromaticContact CD2-CD1 3.82Å; Y206-Y209 HydrophobicContact CD2-CD1 3.82Å; Y206-Y209 HydrophobicContact CD2-CE1 4.41Å; Y206-Y209 AromaticContact CE2-CD1 3.82Å; Y206-Y209 HydrophobicContact CE2-CD1 3.82Å; Y206-Y209 HydrophobicContact CE2-CE1 4Å; Y206-Y209 PolarHBondContact O-N 2.85Å; Y206-S210 VanDerWaalsContact CE1-OG 3.3Å; Y206-S210 WeakPolarHBondContact CE1-OG 3.2Å; Y206-S210 WeakPolarHBondContact O-CB 3.46Å; Y206-S210 PolarHBondContact O-N 3.34Å; Y206-S210 PolarHBondContact O-OG 3.4Å
207	A	86.9	Confident	87.4	Confident	31 Å²	31	66.9 Å²	66.9	26%	0.256	33%	0.328	S	S	.	.	H	α-helix	trans	-61.1	-47.3	173.3	0	0	0	0	0	111.6	S203 T204 Y205 S210 W211	S203-A207 PolarHBondContact O-N 3.01Å; T204-A207 WeakPolarHBondContact O-CB 3.18Å; T204-A207 PolarHBondContact O-N 3.22Å; Y205-A207 VanDerWaalsContact C-N 3.32Å; Y205-A207 PolarHBondContact O-N 2.98Å; A207-S210 WeakPolarHBondContact O-CB 3.43Å; A207-S210 PolarHBondContact O-N 2.78Å; A207-W211 VanDerWaalsContact O-CD1 3.23Å; A207-W211 PolarHBondContact O-N 2.88Å
208	F	89.9	Confident	87.6	Confident	138 Å²	138	63.4 Å²	63.4	61%	0.605	31%	0.31	S	S	*	.	H	α-helix	trans	-61.3	-47.7	175.5	-179.7	-105.8	0	0	0	112.1	T204 Y205 S210 W211 L212	T204-F208 PolarHBondContact O-N 2.98Å; Y205-F208 PolarHBondContact O-N 3.36Å; F208-S210 VanDerWaalsContact C-N 3.31Å; F208-S210 PolarHBondContact O-N 2.82Å; F208-W211 PolarHBondContact O-N 3.35Å; F208-L212 HydrophobicContact CD1-CD1 4.03Å; F208-L212 HydrophobicContact CD1-CG 4.42Å; F208-L212 HydrophobicContact CE1-CD1 3.48Å; F208-L212 VanDerWaalsContact CE1-CD1 3.48Å; F208-L212 HydrophobicContact CE1-CG 4.06Å; F208-L212 HydrophobicContact CZ-CD1 3.96Å; F208-L212 HydrophobicContact CZ-CD2 4.23Å; F208-L212 HydrophobicContact CZ-CG 4.17Å; F208-L212 PolarHBondContact O-N 3.34Å
209	Y	89.9	Confident	87.7	Confident	31 Å²	31	66 Å²	66	12%	0.122	32%	0.322	C	S	.	.	H	α-helix	trans	-57.1	-42.5	174.4	163.3	-97.3	0	0	0	112.5	F172 P175 Y205 Y206 W211 L212 R213	F172-Y209 HydrophobicContact CE1-CE2 4.35Å; F172-Y209 HydrophobicContact CE2-CE2 4.36Å; F172-Y209 HydrophobicContact CZ-CE2 4.2Å; F172-Y209 WeakPolarHBondContact O-CE2 3.39Å; F172-Y209 PolarHBondContact O-OH 3.3Å; P175-Y209 HydrophobicContact CB-CD1 4.42Å; P175-Y209 HydrophobicContact CB-CE1 3.91Å; P175-Y209 HydrophobicContact CG-CD2 4.45Å; P175-Y209 HydrophobicContact CG-CE1 4.23Å; P175-Y209 HydrophobicContact CG-CE2 3.92Å; Y205-Y209 WeakPolarHBondContact O-CB 3.39Å; Y205-Y209 PolarHBondContact O-N 3.49Å; Y206-Y209 AromaticContact CD2-CD1 3.82Å; Y206-Y209 HydrophobicContact CD2-CD1 3.82Å; Y206-Y209 HydrophobicContact CD2-CE1 4.41Å; Y206-Y209 AromaticContact CE2-CD1 3.82Å; Y206-Y209 HydrophobicContact CE2-CD1 3.82Å; Y206-Y209 HydrophobicContact CE2-CE1 4Å; Y206-Y209 PolarHBondContact O-N 2.85Å; Y209-W211 VanDerWaalsContact C-N 3.28Å; Y209-W211 PolarHBondContact O-N 3.46Å; Y209-L212 PolarHBondContact O-N 2.89Å; Y209-R213 PolarHBondContact O-N 3.48Å
210	S	86.3	Confident	87.9	Confident	9 Å²	9	63.9 Å²	63.9	6%	0.063	30%	0.301	C	S	.	.	H	α-helix	trans	-60.3	-39.5	178.9	-62.7	0	0	0	0	111.6	Y206 A207 F208 R213 I214	Y206-S210 VanDerWaalsContact CE1-OG 3.3Å; Y206-S210 WeakPolarHBondContact CE1-OG 3.2Å; Y206-S210 WeakPolarHBondContact O-CB 3.46Å; Y206-S210 PolarHBondContact O-N 3.34Å; Y206-S210 PolarHBondContact O-OG 3.4Å; A207-S210 WeakPolarHBondContact O-CB 3.43Å; A207-S210 PolarHBondContact O-N 2.78Å; F208-S210 VanDerWaalsContact C-N 3.31Å; F208-S210 PolarHBondContact O-N 2.82Å; S210-R213 PolarHBondContact O-N 3.48Å; S210-I214 WeakPolarHBondContact O-CD1 3.38Å; S210-I214 VanDerWaalsContact O-CG1 3.29Å; S210-I214 WeakPolarHBondContact O-CG1 3.39Å; S210-I214 PolarHBondContact O-N 2.92Å
211	W	89.9	Confident	88	Confident	117 Å²	117	60.4 Å²	60.4	44%	0.443	29%	0.286	S	S	.	.	H	α-helix	trans	-67.3	-45.3	174.3	-79.4	113.8	0	0	0	112.5	A207 F208 Y209 R213 I214 V215 T394	A207-W211 VanDerWaalsContact O-CD1 3.23Å; A207-W211 PolarHBondContact O-N 2.88Å; F208-W211 PolarHBondContact O-N 3.35Å; Y209-W211 VanDerWaalsContact C-N 3.28Å; Y209-W211 PolarHBondContact O-N 3.46Å; W211-R213 PolarHBondContact O-N 3.38Å; W211-I214 HydrophobicContact CE3-CD1 4.17Å; W211-I214 HydrophobicContact CZ3-CD1 4.47Å; W211-I214 PolarHBondContact O-N 3.33Å; W211-I214 VanDerWaalsContact O-N 3.16Å; W211-V215 WeakPolarHBondContact O-CG2 3.31Å; W211-V215 PolarHBondContact O-N 3.22Å; W211-T394 HydrophobicContact CH2-CG2 3.55Å; W211-T394 HydrophobicContact CZ2-CG2 3.71Å
212	L	89.7	Confident	88.3	Confident	61 Å²	61	60.8 Å²	60.8	32%	0.319	29%	0.287	S	S	.	.	H	α-helix	trans	-57.4	-41.1	174.5	-69.8	-176.1	0	0	0	111.5	F208 Y209 V215 F216	F208-L212 HydrophobicContact CD1-CD1 4.03Å; F208-L212 HydrophobicContact CD1-CG 4.42Å; F208-L212 HydrophobicContact CE1-CD1 3.48Å; F208-L212 VanDerWaalsContact CE1-CD1 3.48Å; F208-L212 HydrophobicContact CE1-CG 4.06Å; F208-L212 HydrophobicContact CZ-CD1 3.96Å; F208-L212 HydrophobicContact CZ-CD2 4.23Å; F208-L212 HydrophobicContact CZ-CG 4.17Å; F208-L212 PolarHBondContact O-N 3.34Å; Y209-L212 PolarHBondContact O-N 2.89Å; L212-V215 PolarHBondContact O-N 3.2Å; L212-F216 HydrophobicContact CB-CD2 4.29Å; L212-F216 HydrophobicContact CD2-CE2 4.11Å; L212-F216 WeakPolarHBondContact O-CB 3.46Å; L212-F216 VanDerWaalsContact O-CD2 3.22Å; L212-F216 WeakPolarHBondContact O-CD2 3.25Å; L212-F216 PolarHBondContact O-N 3.17Å
213	R	87.8	Confident	88.6	Confident	3 Å²	3	55.5 Å²	55.5	1%	0.011	28%	0.278	C	S	.	.	H	α-helix	trans	-59.9	-51.3	174.5	174.2	-169.9	179.3	77.6	-1.4	111.8	N122 F172 N173 Y176 Y209 S210 W211 V215 F216 V217	N122-R213 PolarHBondContact OD1-NH2 2.84Å; F172-R213 HydrophobicContact CE1-CB 3.69Å; F172-R213 HydrophobicContact CE1-CG 3.92Å; F172-R213 HydrophobicContact CZ-CB 4.02Å; N173-R213 PolarHBondContact OD1-NH1 3.03Å; Y176-R213 WeakPolarHBondContact OH-CD 3.48Å; Y176-R213 PolarHBondContact OH-NE 3.23Å; Y209-R213 PolarHBondContact O-N 3.48Å; S210-R213 PolarHBondContact O-N 3.48Å; W211-R213 PolarHBondContact O-N 3.38Å; R213-V215 PolarHBondContact O-N 3.46Å; R213-F216 PolarHBondContact O-N 3.08Å; R213-V217 HydrophobicContact CG-CB 4.14Å; R213-V217 HydrophobicContact CG-CG2 4.05Å; R213-V217 WeakPolarHBondContact O-CA 3.37Å; R213-V217 VanDerWaalsContact O-CB 3.27Å; R213-V217 WeakPolarHBondContact O-CB 3.44Å; R213-V217 PolarHBondContact O-N 3.46Å
214	I	88.1	Confident	88.7	Confident	13 Å²	13	58 Å²	58	7%	0.067	29%	0.285	C	S	.	.	I	π-helix	trans	-54.9	-43.6	179.7	-69.8	159.5	0	0	0	109.3	S210 W211 Q218 I219 R390 V391	S210-I214 WeakPolarHBondContact O-CD1 3.38Å; S210-I214 VanDerWaalsContact O-CG1 3.29Å; S210-I214 WeakPolarHBondContact O-CG1 3.39Å; S210-I214 PolarHBondContact O-N 2.92Å; W211-I214 HydrophobicContact CE3-CD1 4.17Å; W211-I214 HydrophobicContact CZ3-CD1 4.47Å; W211-I214 PolarHBondContact O-N 3.33Å; W211-I214 VanDerWaalsContact O-N 3.16Å; I214-Q218 WeakPolarHBondContact O-CA 3.46Å; I214-Q218 VanDerWaalsContact O-CB 3.28Å; I214-Q218 WeakPolarHBondContact O-CB 3.44Å; I214-Q218 PolarHBondContact O-N 3.32Å; I214-I219 HydrophobicContact CG2-CG1 4.03Å; I214-I219 PolarHBondContact O-N 2.87Å; I214-R390 HydrophobicContact CD1-CB 4.01Å; I214-V391 HydrophobicContact CD1-CG2 3.64Å; I214-V391 HydrophobicContact CG1-CG2 3.95Å; I214-V391 HydrophobicContact CG2-CG2 3.8Å
215	V	89.9	Confident	88.8	Confident	60 Å²	60	52.6 Å²	52.6	36%	0.364	25%	0.252	S	S	.	.	I	π-helix	trans	-65.4	-54.1	178.2	174.9	0	0	0	0	112.3	W211 L212 R213 I219 I220	W211-V215 WeakPolarHBondContact O-CG2 3.31Å; W211-V215 PolarHBondContact O-N 3.22Å; L212-V215 PolarHBondContact O-N 3.2Å; R213-V215 PolarHBondContact O-N 3.46Å; V215-I219 PolarHBondContact O-N 3.44Å; V215-I220 HydrophobicContact CG1-CD1 3.72Å; V215-I220 HydrophobicContact CG1-CG1 4.11Å; V215-I220 WeakPolarHBondContact O-CB 3.22Å; V215-I220 WeakPolarHBondContact O-CG1 3.35Å; V215-I220 PolarHBondContact O-N 3.29Å
216	F	89.2	Confident	88.8	Confident	96 Å²	96	46.6 Å²	46.6	42%	0.421	24%	0.236	S	C	.	.	I	π-helix	trans	-81.1	-30.2	-171.2	-74.4	-64	0	0	0	115	W130 L212 R213 I220 P221	W130-F216 WeakPolarHBondContact CZ2-O 3.35Å; L212-F216 HydrophobicContact CB-CD2 4.29Å; L212-F216 HydrophobicContact CD2-CE2 4.11Å; L212-F216 WeakPolarHBondContact O-CB 3.46Å; L212-F216 VanDerWaalsContact O-CD2 3.22Å; L212-F216 WeakPolarHBondContact O-CD2 3.25Å; L212-F216 PolarHBondContact O-N 3.17Å; R213-F216 PolarHBondContact O-N 3.08Å; F216-I220 HydrophobicContact CD1-CD1 3.66Å; F216-I220 HydrophobicContact CE1-CD1 3.89Å; F216-P221 VanDerWaalsContact O-CD 3.24Å; F216-P221 WeakPolarHBondContact O-CD 3.33Å; F216-P221 WeakPolarHBondContact O-CG 3.46Å
217	V	85.5	Confident	89	Confident	12 Å²	12	49.9 Å²	49.9	7%	0.073	26%	0.258	C	S	.	.	I	π-helix	trans	-98.7	-24.6	-174.9	178.3	0	0	0	0	111.6	N126 F172 R213	N126-V217 HydrophobicContact CB-CG1 3.88Å; N126-V217 WeakPolarHBondContact OD1-CG1 3.34Å; F172-V217 HydrophobicContact CD1-CG2 3.76Å; F172-V217 HydrophobicContact CE1-CG2 3.49Å; F172-V217 VanDerWaalsContact CE1-CG2 3.49Å; F172-V217 HydrophobicContact CZ-CG2 4.49Å; R213-V217 HydrophobicContact CG-CB 4.14Å; R213-V217 HydrophobicContact CG-CG2 4.05Å; R213-V217 WeakPolarHBondContact O-CA 3.37Å; R213-V217 VanDerWaalsContact O-CB 3.27Å; R213-V217 WeakPolarHBondContact O-CB 3.44Å; R213-V217 PolarHBondContact O-N 3.46Å
218	Q	85.9	Confident	89	Confident	10 Å²	10	48.8 Å²	48.8	5%	0.047	25%	0.249	C	C	.	.	I	π-helix	trans	-117.4	-67.9	-175.6	-53.7	167.5	-2.6	0	0	111	I214 P221 L222 Y388	I214-Q218 WeakPolarHBondContact O-CA 3.46Å; I214-Q218 VanDerWaalsContact O-CB 3.28Å; I214-Q218 WeakPolarHBondContact O-CB 3.44Å; I214-Q218 PolarHBondContact O-N 3.32Å; Q218-P221 WeakPolarHBondContact O-CD 2.96Å; Q218-L222 WeakPolarHBondContact O-CB 3.42Å; Q218-L222 WeakPolarHBondContact O-CD1 3.27Å; Q218-L222 WeakPolarHBondContact O-CG 3.17Å; Q218-L222 PolarHBondContact O-N 2.8Å; Q218-Y388 VanDerWaalsContact NE2-CE1 3.31Å
219	I	88.6	Confident	88.7	Confident	80 Å²	80	42.6 Å²	42.6	41%	0.41	22%	0.222	S	C	.	.	I	π-helix	trans	-62.8	-52.6	-170.2	-59.4	-61.9	0	0	0	112	I214 V215 L222 C223	I214-I219 HydrophobicContact CG2-CG1 4.03Å; I214-I219 PolarHBondContact O-N 2.87Å; V215-I219 PolarHBondContact O-N 3.44Å; I219-L222 PolarHBondContact O-N 3.23Å; I219-C223 VanDerWaalsContact O-CB 3.27Å; I219-C223 WeakPolarHBondContact O-CB 3.17Å; I219-C223 PolarHBondContact O-N 2.76Å; I219-C223 PolarHBondContact O-SG 3.45Å
220	I	90.9	Very high	88.7	Confident	67 Å²	67	44.9 Å²	44.9	34%	0.344	24%	0.241	S	C	.	.	H	α-helix	trans	-60.5	-52.5	-178.3	-72.6	170.4	0	0	0	111.4	W130 V215 F216 L222 F224	W130-I220 HydrophobicContact CH2-CG2 4.1Å; V215-I220 HydrophobicContact CG1-CD1 3.72Å; V215-I220 HydrophobicContact CG1-CG1 4.11Å; V215-I220 WeakPolarHBondContact O-CB 3.22Å; V215-I220 WeakPolarHBondContact O-CG1 3.35Å; V215-I220 PolarHBondContact O-N 3.29Å; F216-I220 HydrophobicContact CD1-CD1 3.66Å; F216-I220 HydrophobicContact CE1-CD1 3.89Å; I220-L222 PolarHBondContact O-N 3.28Å; I220-F224 VanDerWaalsContact O-CB 3.23Å; I220-F224 WeakPolarHBondContact O-CB 3.27Å; I220-F224 PolarHBondContact O-N 3.44Å
221	P	90.1	Very high	88.9	Confident	1 Å²	1	48.1 Å²	48.1	1%	0.006	26%	0.258	C	S	.	.	H	α-helix	trans	-58	-46	176.7	-28.4	37.2	0	0	0	112.7	A129 W130 V133 F216 Q218 F224 L225	A129-P221 HydrophobicContact CB-CB 4.38Å; W130-P221 HydrophobicContact CD2-CG 4.47Å; W130-P221 HydrophobicContact CH2-CG 4.4Å; W130-P221 HydrophobicContact CZ2-CG 3.94Å; V133-P221 HydrophobicContact CG2-CB 3.99Å; F216-P221 VanDerWaalsContact O-CD 3.24Å; F216-P221 WeakPolarHBondContact O-CD 3.33Å; F216-P221 WeakPolarHBondContact O-CG 3.46Å; Q218-P221 WeakPolarHBondContact O-CD 2.96Å; P221-F224 PolarHBondContact O-N 2.73Å; P221-L225 WeakPolarHBondContact O-CB 3.35Å; P221-L225 WeakPolarHBondContact O-CG 3.43Å; P221-L225 PolarHBondContact O-N 2.8Å
222	L	88.2	Confident	88.8	Confident	17 Å²	17	42.5 Å²	42.5	9%	0.089	24%	0.236	C	C	.	.	H	α-helix	trans	-65.2	-47.3	-178.5	-67.9	173.3	0	0	0	112	Q218 I219 I220 F224 L225 C226 F377 L378 Q381 V382	Q218-L222 WeakPolarHBondContact O-CB 3.42Å; Q218-L222 WeakPolarHBondContact O-CD1 3.27Å; Q218-L222 WeakPolarHBondContact O-CG 3.17Å; Q218-L222 PolarHBondContact O-N 2.8Å; I219-L222 PolarHBondContact O-N 3.23Å; I220-L222 PolarHBondContact O-N 3.28Å; L222-F224 VanDerWaalsContact C-N 3.34Å; L222-F224 PolarHBondContact O-N 2.97Å; L222-L225 PolarHBondContact O-N 2.88Å; L222-C226 WeakPolarHBondContact O-CB 3.37Å; L222-C226 PolarHBondContact O-N 3.01Å; L222-C226 PolarHBondContact O-SG 3.34Å; L222-F377 HydrophobicContact CD2-CE1 4.28Å; L222-L378 HydrophobicContact CD2-CD2 3.71Å; L222-Q381 HydrophobicContact CD2-CB 4.13Å; L222-V382 HydrophobicContact CD1-CG2 4.15Å; L222-V382 HydrophobicContact CD2-CG2 3.73Å; L222-V382 HydrophobicContact CG-CG2 4.35Å
223	C	89.6	Confident	88.7	Confident	72 Å²	72	45.8 Å²	45.8	49%	0.486	25%	0.248	S	C	.	.	H	α-helix	trans	-60.2	-44.7	176	-70.9	0	0	0	0	111.3	I219 L225 C226 V227	I219-C223 VanDerWaalsContact O-CB 3.27Å; I219-C223 WeakPolarHBondContact O-CB 3.17Å; I219-C223 PolarHBondContact O-N 2.76Å; I219-C223 PolarHBondContact O-SG 3.45Å; C223-L225 PolarHBondContact O-N 3.48Å; C223-C226 PolarHBondContact O-N 2.94Å; C223-V227 WeakPolarHBondContact O-CG2 3.44Å; C223-V227 PolarHBondContact O-N 3.41Å
224	F	91.9	Very high	88.8	Confident	81 Å²	81	50.7 Å²	50.7	36%	0.355	27%	0.274	S	S	.	.	H	α-helix	trans	-61.2	-44.8	176.5	-177.3	-85.3	0	0	0	111.6	V133 A136 I137 I220 P221 L222 V227 S228	V133-F224 HydrophobicContact CB-CD1 4.28Å; V133-F224 HydrophobicContact CG1-CD1 3.63Å; V133-F224 HydrophobicContact CG1-CE1 3.77Å; V133-F224 HydrophobicContact CG1-CG 4.3Å; V133-F224 HydrophobicContact CG2-CD1 4.08Å; A136-F224 HydrophobicContact CB-CE1 4.31Å; I137-F224 HydrophobicContact CD1-CE1 4.18Å; I137-F224 HydrophobicContact CD1-CZ 3.87Å; I137-F224 HydrophobicContact CG1-CE1 3.69Å; I137-F224 HydrophobicContact CG1-CE2 4.45Å; I137-F224 HydrophobicContact CG1-CZ 3.39Å; I220-F224 VanDerWaalsContact O-CB 3.23Å; I220-F224 WeakPolarHBondContact O-CB 3.27Å; I220-F224 PolarHBondContact O-N 3.44Å; P221-F224 PolarHBondContact O-N 2.73Å; L222-F224 VanDerWaalsContact C-N 3.34Å; L222-F224 PolarHBondContact O-N 2.97Å; F224-V227 PolarHBondContact O-N 3.26Å; F224-S228 WeakPolarHBondContact O-CB 3.48Å; F224-S228 PolarHBondContact O-N 3.41Å; F224-S228 PolarHBondContact O-OG 3.36Å
225	L	90.4	Very high	88.7	Confident	0 Å²	0	51.9 Å²	51.9	0%	0	28%	0.28	C	S	.	.	H	α-helix	trans	-65	-41	178.4	-72	-179.8	0	0	0	111.9	T132 V133 A136 P221 L222 C223 S228 N229 I374 F377 L378	T132-L225 HydrophobicContact CG2-CD1 3.72Å; T132-L225 HydrophobicContact CG2-CD2 3.89Å; T132-L225 HydrophobicContact CG2-CG 4.47Å; V133-L225 HydrophobicContact CB-CD2 4.44Å; V133-L225 HydrophobicContact CG2-CD1 4.41Å; V133-L225 HydrophobicContact CG2-CD2 3.9Å; V133-L225 HydrophobicContact CG2-CG 3.91Å; A136-L225 HydrophobicContact CB-CD2 3.99Å; P221-L225 WeakPolarHBondContact O-CB 3.35Å; P221-L225 WeakPolarHBondContact O-CG 3.43Å; P221-L225 PolarHBondContact O-N 2.8Å; L222-L225 PolarHBondContact O-N 2.88Å; C223-L225 PolarHBondContact O-N 3.48Å; L225-S228 WeakPolarHBondContact CA-OG 3.33Å; L225-S228 PolarHBondContact O-OG 3.16Å; L225-N229 WeakPolarHBondContact O-CB 3.5Å; L225-N229 PolarHBondContact O-N 3.1Å; L225-N229 PolarHBondContact O-ND2 3.35Å; L225-I374 HydrophobicContact CB-CG2 4.12Å; L225-I374 HydrophobicContact CD1-CG2 4.17Å; L225-I374 HydrophobicContact CD2-CG2 3.72Å; L225-I374 HydrophobicContact CG-CG2 4.2Å; L225-F377 HydrophobicContact CD1-CD1 3.72Å; L225-F377 HydrophobicContact CD1-CE1 3.68Å; L225-L378 HydrophobicContact CB-CD1 4.38Å; L225-L378 HydrophobicContact CB-CD2 3.84Å; L225-L378 HydrophobicContact CB-CG 4.34Å; L225-L378 HydrophobicContact CD1-CD2 4.36Å
226	C	88.9	Confident	88.5	Confident	57 Å²	57	49.5 Å²	49.5	39%	0.385	27%	0.265	S	S	.	.	H	α-helix	trans	-59.6	-51.4	174.2	-71.4	0	0	0	0	111.4	L222 C223 N229 C230	L222-C226 WeakPolarHBondContact O-CB 3.37Å; L222-C226 PolarHBondContact O-N 3.01Å; L222-C226 PolarHBondContact O-SG 3.34Å; C223-C226 PolarHBondContact O-N 2.94Å; C226-N229 PolarHBondContact O-N 3.43Å; C226-C230 PolarHBondContact O-N 3.24Å; C226-C230 VanDerWaalsContact O-N 3.08Å; C226-C230 PolarHBondContact O-SG 2.94Å
227	V	90.6	Very high	88.5	Confident	92 Å²	92	47 Å²	47	56%	0.558	26%	0.26	S	S	*	.	H	α-helix	trans	-63.4	-48.6	179.6	173.3	0	0	0	0	111	C223 F224 N229 C230 L231	C223-V227 WeakPolarHBondContact O-CG2 3.44Å; C223-V227 PolarHBondContact O-N 3.41Å; F224-V227 PolarHBondContact O-N 3.26Å; V227-N229 PolarHBondContact O-N 3.18Å; V227-C230 WeakPolarHBondContact O-CB 3.08Å; V227-C230 PolarHBondContact O-N 3.28Å; V227-L231 HydrophobicContact CG1-CD1 4.01Å; V227-L231 HydrophobicContact CG1-CG 4.49Å; V227-L231 WeakPolarHBondContact O-CG 3.22Å; V227-L231 PolarHBondContact O-N 3.39Å
228	S	87.6	Confident	88.5	Confident	8 Å²	8	52.7 Å²	52.7	6%	0.056	29%	0.285	C	S	.	.	H	α-helix	trans	-65.8	-36.6	-178.4	61.3	0	0	0	0	112.5	F224 L225 L231 L232	F224-S228 WeakPolarHBondContact O-CB 3.48Å; F224-S228 PolarHBondContact O-N 3.41Å; F224-S228 PolarHBondContact O-OG 3.36Å; L225-S228 WeakPolarHBondContact CA-OG 3.33Å; L225-S228 PolarHBondContact O-OG 3.16Å; S228-L231 PolarHBondContact O-N 3.23Å; S228-L232 WeakPolarHBondContact O-CB 3.45Å; S228-L232 VanDerWaalsContact O-CG 3.23Å; S228-L232 WeakPolarHBondContact O-CG 3.37Å; S228-L232 PolarHBondContact O-N 3.49Å
229	N	84.6	Confident	88.4	Confident	7 Å²	7	54.3 Å²	54.3	4%	0.037	29%	0.293	C	S	.	.	H	α-helix	trans	-65.9	-41.4	173.5	-79.3	-37.3	0	0	0	112.7	L225 C226 V227 L231 L232 F233 I374 L378	L225-N229 WeakPolarHBondContact O-CB 3.5Å; L225-N229 PolarHBondContact O-N 3.1Å; L225-N229 PolarHBondContact O-ND2 3.35Å; C226-N229 PolarHBondContact O-N 3.43Å; V227-N229 PolarHBondContact O-N 3.18Å; N229-L231 VanDerWaalsContact C-N 3.3Å; N229-L231 PolarHBondContact O-N 3.48Å; N229-L232 PolarHBondContact O-N 3.35Å; N229-F233 VanDerWaalsContact O-CB 3.22Å; N229-F233 WeakPolarHBondContact O-CB 3.27Å; N229-F233 PolarHBondContact O-N 3.36Å; N229-I374 WeakPolarHBondContact ND2-CG2 3.45Å; N229-I374 WeakPolarHBondContact OD1-CB 3.46Å; N229-I374 WeakPolarHBondContact OD1-CD1 3.27Å; N229-I374 WeakPolarHBondContact OD1-CG2 3.4Å; N229-L378 VanDerWaalsContact ND2-CD1 3.27Å; N229-L378 WeakPolarHBondContact ND2-CD1 3.39Å
230	C	89.5	Confident	88.2	Confident	79 Å²	79	52.3 Å²	52.3	53%	0.534	28%	0.283	S	S	.	.	H	α-helix	trans	-58.5	-46.5	172.8	-71.2	0	0	0	0	110.3	C226 V227 F233 I234	C226-C230 PolarHBondContact O-N 3.24Å; C226-C230 VanDerWaalsContact O-N 3.08Å; C226-C230 PolarHBondContact O-SG 2.94Å; V227-C230 WeakPolarHBondContact O-CB 3.08Å; V227-C230 PolarHBondContact O-N 3.28Å; C230-F233 PolarHBondContact O-N 2.82Å; C230-I234 WeakPolarHBondContact O-CB 3.24Å; C230-I234 WeakPolarHBondContact O-CD1 3.35Å; C230-I234 WeakPolarHBondContact O-CG1 3.46Å; C230-I234 PolarHBondContact O-N 3.34Å
231	L	89.6	Confident	87.9	Confident	77 Å²	77	57.7 Å²	57.7	40%	0.403	30%	0.299	S	S	.	.	H	α-helix	trans	-62.9	-43.8	177.1	-68.5	172.2	0	0	0	112.6	Y140 V227 S228 N229 I234 L235	Y140-L231 HydrophobicContact CD2-CB 4.44Å; Y140-L231 HydrophobicContact CE2-CB 4.19Å; V227-L231 HydrophobicContact CG1-CD1 4.01Å; V227-L231 HydrophobicContact CG1-CG 4.49Å; V227-L231 WeakPolarHBondContact O-CG 3.22Å; V227-L231 PolarHBondContact O-N 3.39Å; S228-L231 PolarHBondContact O-N 3.23Å; N229-L231 VanDerWaalsContact C-N 3.3Å; N229-L231 PolarHBondContact O-N 3.48Å; L231-I234 PolarHBondContact O-N 2.91Å; L231-L235 WeakPolarHBondContact O-CB 3.37Å; L231-L235 PolarHBondContact O-N 3.44Å
232	L	87.7	Confident	87.7	Confident	0 Å²	0	65.4 Å²	65.4	0%	0	33%	0.328	C	S	.	.	H	α-helix	trans	-64	-43.1	177.4	-76.1	172.3	0	0	0	111.3	A136 R139 Y140 S228 N229 L235 V236 T367 I371 I374	A136-L232 HydrophobicContact CB-CD1 4.39Å; R139-L232 HydrophobicContact CB-CD1 4.39Å; R139-L232 HydrophobicContact CB-CD2 4Å; Y140-L232 HydrophobicContact CD2-CD2 4.39Å; S228-L232 WeakPolarHBondContact O-CB 3.45Å; S228-L232 VanDerWaalsContact O-CG 3.23Å; S228-L232 WeakPolarHBondContact O-CG 3.37Å; S228-L232 PolarHBondContact O-N 3.49Å; N229-L232 PolarHBondContact O-N 3.35Å; L232-L235 PolarHBondContact O-N 2.91Å; L232-V236 WeakPolarHBondContact O-CB 3.42Å; L232-V236 VanDerWaalsContact O-CG2 3.3Å; L232-V236 WeakPolarHBondContact O-CG2 3.39Å; L232-V236 PolarHBondContact O-N 2.93Å; L232-T367 HydrophobicContact CD2-CG2 4.5Å; L232-I371 HydrophobicContact CB-CD1 4.02Å; L232-I371 HydrophobicContact CB-CG1 4.02Å; L232-I374 HydrophobicContact CD1-CD1 4.32Å
233	F	88.5	Confident	87.3	Confident	129 Å²	129	66.9 Å²	66.9	57%	0.566	33%	0.334	S	S	*	.	H	α-helix	trans	-63.6	-46.7	177.2	-179.5	-95	0	0	0	111.6	N229 C230 L235 V236 S237	N229-F233 VanDerWaalsContact O-CB 3.22Å; N229-F233 WeakPolarHBondContact O-CB 3.27Å; N229-F233 PolarHBondContact O-N 3.36Å; C230-F233 PolarHBondContact O-N 2.82Å; F233-L235 VanDerWaalsContact C-N 3.32Å; F233-L235 PolarHBondContact O-N 2.97Å; F233-V236 PolarHBondContact O-N 2.97Å; F233-S237 VanDerWaalsContact O-CB 3.28Å; F233-S237 WeakPolarHBondContact O-CB 3.33Å; F233-S237 PolarHBondContact O-N 2.9Å; F233-S237 PolarHBondContact O-OG 3.23Å
234	I	88.8	Confident	87	Confident	107 Å²	107	67.9 Å²	67.9	55%	0.549	34%	0.338	S	S	.	.	H	α-helix	trans	-59.8	-45.4	175.3	-69.6	165.4	0	0	0	110	C230 L231 V236 S237 H238	C230-I234 WeakPolarHBondContact O-CB 3.24Å; C230-I234 WeakPolarHBondContact O-CD1 3.35Å; C230-I234 WeakPolarHBondContact O-CG1 3.46Å; C230-I234 PolarHBondContact O-N 3.34Å; L231-I234 PolarHBondContact O-N 2.91Å; I234-V236 PolarHBondContact O-N 3.14Å; I234-S237 PolarHBondContact O-N 3.02Å; I234-H238 WeakPolarHBondContact O-CB 3.02Å; I234-H238 PolarHBondContact O-N 3.32Å
235	L	86.3	Confident	86.6	Confident	38 Å²	38	67.2 Å²	67.2	20%	0.199	34%	0.338	C	S	.	.	H	α-helix	trans	-62	-45.8	-179.8	-171.8	153.8	0	0	0	111.6	Y140 M143 K144 L231 L232 F233 H239	Y140-L235 HydrophobicContact CD2-CD1 4.4Å; Y140-L235 HydrophobicContact CE2-CD1 4.28Å; M143-L235 HydrophobicContact CB-CD1 4.38Å; M143-L235 HydrophobicContact CB-CD2 3.66Å; M143-L235 HydrophobicContact CE-CD2 3.25Å; M143-L235 HydrophobicContact CG-CD2 4.29Å; M143-L235 HydrophobicContact SD-CD2 3.63Å; K144-L235 HydrophobicContact CB-CD1 4.02Å; L231-L235 WeakPolarHBondContact O-CB 3.37Å; L231-L235 PolarHBondContact O-N 3.44Å; L232-L235 PolarHBondContact O-N 2.91Å; F233-L235 VanDerWaalsContact C-N 3.32Å; F233-L235 PolarHBondContact O-N 2.97Å; L235-H239 WeakPolarHBondContact O-CB 3.41Å; L235-H239 PolarHBondContact O-N 3.46Å
236	V	86.9	Confident	86.3	Confident	9 Å²	9	70.9 Å²	70.9	6%	0.055	36%	0.358	C	S	.	.	H	α-helix	trans	-62.8	-43.6	175.5	169.7	0	0	0	0	110.8	M143 L232 F233 I234 H239 N240 T367 I368 I371	M143-V236 HydrophobicContact CE-CG2 3.75Å; M143-V236 HydrophobicContact SD-CG2 4.21Å; L232-V236 WeakPolarHBondContact O-CB 3.42Å; L232-V236 VanDerWaalsContact O-CG2 3.3Å; L232-V236 WeakPolarHBondContact O-CG2 3.39Å; L232-V236 PolarHBondContact O-N 2.93Å; F233-V236 PolarHBondContact O-N 2.97Å; I234-V236 PolarHBondContact O-N 3.14Å; V236-H239 WeakPolarHBondContact O-CB 3.25Å; V236-H239 PolarHBondContact O-N 2.68Å; V236-N240 WeakPolarHBondContact O-CB 3.42Å; V236-N240 PolarHBondContact O-N 2.86Å; V236-N240 PolarHBondContact O-ND2 2.66Å; V236-N240 PolarHBondContact O-OD1 2.7Å; V236-N240 VanDerWaalsContact O-OD1 3.12Å; V236-T367 HydrophobicContact CG2-CG2 3.61Å; V236-I368 HydrophobicContact CG1-CG1 4.37Å; V236-I371 HydrophobicContact CG2-CD1 3.87Å
237	S	87.9	Confident	85.9	Confident	44 Å²	44	75 Å²	75	31%	0.308	37%	0.369	S	S	.	.	H	α-helix	trans	-64.7	-44.3	-178.9	-62.1	0	0	0	0	111.9	F233 I234 H239 N240 R241	F233-S237 VanDerWaalsContact O-CB 3.28Å; F233-S237 WeakPolarHBondContact O-CB 3.33Å; F233-S237 PolarHBondContact O-N 2.9Å; F233-S237 PolarHBondContact O-OG 3.23Å; I234-S237 PolarHBondContact O-N 3.02Å; S237-H239 PolarHBondContact O-N 3.22Å; S237-N240 PolarHBondContact O-N 3.27Å; S237-R241 PolarHBondContact O-N 3.29Å
238	H	86.7	Confident	85.6	Confident	131 Å²	131	76.1 Å²	76.1	61%	0.606	37%	0.369	S	S	*	.	H	α-helix	trans	-61.6	-44.3	174.9	-179.1	-94.8	0	0	0	111.6	I234 N240 R241 R242	I234-H238 WeakPolarHBondContact O-CB 3.02Å; I234-H238 PolarHBondContact O-N 3.32Å; H238-N240 PolarHBondContact O-N 2.72Å; H238-R241 PolarHBondContact O-N 2.97Å; H238-R242 PolarHBondContact O-N 3.07Å; H238-R242 VanDerWaalsContact O-N 3.13Å
239	H	82.2	Confident	85.5	Confident	45 Å²	45	79.6 Å²	79.6	21%	0.208	39%	0.388	C	S	.	.	H	α-helix	trans	-58.6	-48.6	175	-168.5	76.8	0	0	0	110.6	L235 V236 S237 R241 R242 F243	L235-H239 WeakPolarHBondContact O-CB 3.41Å; L235-H239 PolarHBondContact O-N 3.46Å; V236-H239 WeakPolarHBondContact O-CB 3.25Å; V236-H239 PolarHBondContact O-N 2.68Å; S237-H239 PolarHBondContact O-N 3.22Å; H239-R241 PolarHBondContact O-N 3.07Å; H239-R242 WeakPolarHBondContact O-CB 3.45Å; H239-R242 PolarHBondContact O-N 3.42Å; H239-F243 AromaticContact CD2-CD2 3.91Å; H239-F243 AromaticContact CD2-CE2 3.31Å; H239-F243 WeakPolarHBondContact CD2-CE2 3.29Å; H239-F243 AromaticContact CE1-CE2 3.23Å; H239-F243 WeakPolarHBondContact CE1-CE2 3.42Å; H239-F243 AromaticContact CE1-CZ 3.59Å; H239-F243 AromaticContact CG-CE2 3.61Å; H239-F243 AromaticContact ND1-CE2 3.55Å; H239-F243 AromaticContact NE2-CE2 3.07Å; H239-F243 WeakPolarHBondContact NE2-CE2 3.34Å; H239-F243 AromaticContact NE2-CZ 3.58Å; H239-F243 WeakPolarHBondContact O-CD2 3.43Å; H239-F243 PolarHBondContact O-N 3.23Å
240	N	84.5	Confident	85.4	Confident	37 Å²	37	84.1 Å²	84.1	20%	0.198	41%	0.412	C	S	.	.	H	α-helix	trans	-60	-45.2	-179.8	-65.6	-8.3	0	0	0	112.4	V236 S237 H238 R242 F243 T244 R364	V236-N240 WeakPolarHBondContact O-CB 3.42Å; V236-N240 PolarHBondContact O-N 2.86Å; V236-N240 PolarHBondContact O-ND2 2.66Å; V236-N240 PolarHBondContact O-OD1 2.7Å; V236-N240 VanDerWaalsContact O-OD1 3.12Å; S237-N240 PolarHBondContact O-N 3.27Å; H238-N240 PolarHBondContact O-N 2.72Å; N240-R242 VanDerWaalsContact C-N 3.3Å; N240-R242 PolarHBondContact O-N 3.38Å; N240-F243 PolarHBondContact O-N 3.41Å; N240-T244 PolarHBondContact O-N 2.89Å; N240-T244 VanDerWaalsContact O-N 3.09Å; N240-T244 PolarHBondContact O-OG1 3.42Å; N240-R364 VanDerWaalsContact CG-CZ 3.42Å; N240-R364 PolarHBondContact ND2-NH2 2.99Å; N240-R364 VanDerWaalsContact ND2-NH2 3.18Å; N240-R364 PolarHBondContact OD1-NE 2.69Å; N240-R364 PolarHBondContact OD1-NH1 2.62Å; N240-R364 PolarHBondContact OD1-NH2 3.32Å
241	R	85.9	Confident	85.2	Confident	180 Å²	180	84.7 Å²	84.7	68%	0.679	41%	0.409	S	S	*	.	H	α-helix	trans	-59.8	-41.4	177.8	-171.5	176.9	176.7	-170.4	-2.4	111.5	S237 H238 H239 F243 T244 N245	S237-R241 PolarHBondContact O-N 3.29Å; H238-R241 PolarHBondContact O-N 2.97Å; H239-R241 PolarHBondContact O-N 3.07Å; R241-F243 PolarHBondContact O-N 3.47Å; R241-T244 PolarHBondContact O-N 2.97Å; R241-N245 WeakPolarHBondContact O-CB 3.14Å; R241-N245 VanDerWaalsContact O-CG 3.28Å; R241-N245 PolarHBondContact O-N 2.94Å; R241-N245 PolarHBondContact O-OD1 2.96Å
242	R	85.1	Confident	85	Confident	163 Å²	163	83.8 Å²	83.8	62%	0.615	41%	0.407	S	S	*	.	H	α-helix	trans	-62.2	-40.4	176.7	-171.1	178	177	177.9	0.5	112.7	H238 H239 N240 N246	H238-R242 PolarHBondContact O-N 3.07Å; H238-R242 VanDerWaalsContact O-N 3.13Å; H239-R242 WeakPolarHBondContact O-CB 3.45Å; H239-R242 PolarHBondContact O-N 3.42Å; N240-R242 VanDerWaalsContact C-N 3.3Å; N240-R242 PolarHBondContact O-N 3.38Å; R242-N246 WeakPolarHBondContact O-CB 3.23Å; R242-N246 VanDerWaalsContact O-CG 3.28Å; R242-N246 PolarHBondContact O-N 3.36Å; R242-N246 PolarHBondContact O-OD1 3.44Å
243	F	80.2	Confident	84.8	Confident	48 Å²	48	87.7 Å²	87.7	21%	0.211	43%	0.428	C	S	.	.	H	α-helix	trans	-66.9	-42.6	175.9	-74	-76.5	0	0	0	112.8	H239 N240 R241 N245 N246 K247	H239-F243 AromaticContact CD2-CD2 3.91Å; H239-F243 AromaticContact CD2-CE2 3.31Å; H239-F243 WeakPolarHBondContact CD2-CE2 3.29Å; H239-F243 AromaticContact CE1-CE2 3.23Å; H239-F243 WeakPolarHBondContact CE1-CE2 3.42Å; H239-F243 AromaticContact CE1-CZ 3.59Å; H239-F243 AromaticContact CG-CE2 3.61Å; H239-F243 AromaticContact ND1-CE2 3.55Å; H239-F243 AromaticContact NE2-CE2 3.07Å; H239-F243 WeakPolarHBondContact NE2-CE2 3.34Å; H239-F243 AromaticContact NE2-CZ 3.58Å; H239-F243 WeakPolarHBondContact O-CD2 3.43Å; H239-F243 PolarHBondContact O-N 3.23Å; N240-F243 PolarHBondContact O-N 3.41Å; R241-F243 PolarHBondContact O-N 3.47Å; F243-N245 VanDerWaalsContact C-N 3.35Å; F243-N246 PolarHBondContact O-N 3.02Å; F243-K247 WeakPolarHBondContact O-CB 3.48Å; F243-K247 PolarHBondContact O-N 2.87Å
244	T	82.4	Confident	84.4	Confident	93 Å²	93	84.5 Å²	84.5	57%	0.571	42%	0.422	S	S	*	.	H	α-helix	trans	-62.7	-44.8	178.6	-56.2	0	0	0	0	110.8	N240 R241 N246 K247 M248	N240-T244 PolarHBondContact O-N 2.89Å; N240-T244 VanDerWaalsContact O-N 3.09Å; N240-T244 PolarHBondContact O-OG1 3.42Å; R241-T244 PolarHBondContact O-N 2.97Å; T244-N246 PolarHBondContact O-N 3.27Å; T244-K247 PolarHBondContact O-N 3.37Å; T244-M248 WeakPolarHBondContact O-CB 3.42Å; T244-M248 PolarHBondContact O-N 2.8Å
245	N	84.1	Confident	84	Confident	68 Å²	68	87 Å²	87	36%	0.364	43%	0.429	S	S	.	.	H	α-helix	trans	-61.5	-45.2	176.7	-71.5	7.6	0	0	0	111.9	R241 F243 K247 M248 N249	R241-N245 WeakPolarHBondContact O-CB 3.14Å; R241-N245 VanDerWaalsContact O-CG 3.28Å; R241-N245 PolarHBondContact O-N 2.94Å; R241-N245 PolarHBondContact O-OD1 2.96Å; F243-N245 VanDerWaalsContact C-N 3.35Å; N245-K247 VanDerWaalsContact C-N 3.32Å; N245-K247 PolarHBondContact O-N 3.4Å; N245-M248 PolarHBondContact O-N 2.89Å; N245-N249 PolarHBondContact O-N 2.91Å; N245-N249 PolarHBondContact O-OD1 3.13Å
246	N	83.8	Confident	83.5	Confident	77 Å²	77	90.7 Å²	90.7	41%	0.412	45%	0.445	S	S	.	.	H	α-helix	trans	-62.8	-38.3	177	-74.9	6.5	0	0	0	112.4	R242 F243 T244 N250	R242-N246 WeakPolarHBondContact O-CB 3.23Å; R242-N246 VanDerWaalsContact O-CG 3.28Å; R242-N246 PolarHBondContact O-N 3.36Å; R242-N246 PolarHBondContact O-OD1 3.44Å; F243-N246 PolarHBondContact O-N 3.02Å; T244-N246 PolarHBondContact O-N 3.27Å; N246-N250 WeakPolarHBondContact O-CB 3.13Å; N246-N250 VanDerWaalsContact O-CG 3.24Å; N246-N250 PolarHBondContact O-N 3.47Å
247	K	82	Confident	83.1	Confident	144 Å²	144	96 Å²	96	63%	0.626	47%	0.473	S	S	*	.	H	α-helix	trans	-66	-41	175.6	-172.4	176.6	-179.1	179.6	0	111.2	F243 T244 N245 N250 N251	F243-K247 WeakPolarHBondContact O-CB 3.48Å; F243-K247 PolarHBondContact O-N 2.87Å; T244-K247 PolarHBondContact O-N 3.37Å; N245-K247 VanDerWaalsContact C-N 3.32Å; N245-K247 PolarHBondContact O-N 3.4Å; K247-N250 PolarHBondContact O-N 3.3Å; K247-N251 WeakPolarHBondContact O-CB 3.35Å; K247-N251 VanDerWaalsContact O-CG 3.3Å; K247-N251 PolarHBondContact O-N 3.34Å
248	M	82.8	Confident	82.5	Confident	114 Å²	114	99.5 Å²	99.5	56%	0.562	48%	0.483	S	S	*	.	H	α-helix	trans	-64	-47.8	177.4	-166.7	166.4	72.5	0	0	111.2	T244 N245 N250 N251 T252	T244-M248 WeakPolarHBondContact O-CB 3.42Å; T244-M248 PolarHBondContact O-N 2.8Å; N245-M248 PolarHBondContact O-N 2.89Å; M248-N250 PolarHBondContact O-N 3.15Å; M248-N251 WeakPolarHBondContact O-CB 3.43Å; M248-N251 PolarHBondContact O-N 2.96Å; M248-N251 VanDerWaalsContact O-N 3.12Å; M248-T252 WeakPolarHBondContact O-CG2 3.39Å; M248-T252 PolarHBondContact O-N 3.05Å; M248-T252 PolarHBondContact O-OG1 3.44Å
249	N	85.1	Confident	81.9	Confident	82 Å²	82	99 Å²	99	44%	0.439	48%	0.484	S	S	.	.	H	α-helix	trans	-62.1	-39.7	177.3	-70.5	8.1	0	0	0	112.4	N245 N251 T252 N253	N245-N249 PolarHBondContact O-N 2.91Å; N245-N249 PolarHBondContact O-OD1 3.13Å; N249-N251 VanDerWaalsContact C-N 3.3Å; N249-N251 PolarHBondContact O-N 2.63Å; N249-T252 WeakPolarHBondContact CA-OG1 3.38Å; N249-T252 PolarHBondContact O-N 2.96Å; N249-T252 PolarHBondContact O-OG1 2.99Å; N249-N253 WeakPolarHBondContact O-CB 3.47Å; N249-N253 PolarHBondContact O-N 3.36Å; N249-N253 PolarHBondContact O-OD1 3.26Å
250	N	83.3	Confident	81.3	Confident	102 Å²	102	100.7 Å²	100.7	55%	0.545	50%	0.501	S	S	.	.	H	α-helix	trans	-66.2	-34.9	175.7	-74.4	-4.9	0	0	0	112.1	N246 K247 M248 S254	N246-N250 WeakPolarHBondContact O-CB 3.13Å; N246-N250 VanDerWaalsContact O-CG 3.24Å; N246-N250 PolarHBondContact O-N 3.47Å; K247-N250 PolarHBondContact O-N 3.3Å; M248-N250 PolarHBondContact O-N 3.15Å; N250-S254 VanDerWaalsContact O-CB 3.32Å; N250-S254 WeakPolarHBondContact O-CB 3.41Å; N250-S254 PolarHBondContact O-N 2.84Å; N250-S254 PolarHBondContact O-OG 3.28Å
251	N	85.2	Confident	80.2	Confident	90 Å²	90	101.1 Å²	101.1	48%	0.481	51%	0.514	S	S	.	.	H	α-helix	trans	-71.8	-38.8	176.5	-76.6	-5.7	0	0	0	112.4	K247 M248 N249 S254 K255	K247-N251 WeakPolarHBondContact O-CB 3.35Å; K247-N251 VanDerWaalsContact O-CG 3.3Å; K247-N251 PolarHBondContact O-N 3.34Å; M248-N251 WeakPolarHBondContact O-CB 3.43Å; M248-N251 PolarHBondContact O-N 2.96Å; M248-N251 VanDerWaalsContact O-N 3.12Å; N249-N251 VanDerWaalsContact C-N 3.3Å; N249-N251 PolarHBondContact O-N 2.63Å; N251-S254 PolarHBondContact O-N 3.49Å; N251-K255 WeakPolarHBondContact O-CG 3.45Å; N251-K255 PolarHBondContact O-N 2.88Å
252	T	84.5	Confident	78.7	Confident	59 Å²	59	99 Å²	99	36%	0.362	52%	0.516	S	S	.	.	H	α-helix	trans	-64.5	-49.1	174.7	52.3	0	0	0	0	110.6	M248 N249 S254 K255 E256	M248-T252 WeakPolarHBondContact O-CG2 3.39Å; M248-T252 PolarHBondContact O-N 3.05Å; M248-T252 PolarHBondContact O-OG1 3.44Å; N249-T252 WeakPolarHBondContact CA-OG1 3.38Å; N249-T252 PolarHBondContact O-N 2.96Å; N249-T252 PolarHBondContact O-OG1 2.99Å; T252-S254 VanDerWaalsContact C-N 3.27Å; T252-S254 PolarHBondContact O-N 3.45Å; T252-K255 WeakPolarHBondContact O-CA 3.47Å; T252-K255 WeakPolarHBondContact O-CB 3.3Å; T252-K255 PolarHBondContact O-N 3.38Å; T252-E256 PolarHBondContact O-N 3.01Å
253	N	83.6	Confident	77.2	Confident	81 Å²	81	97 Å²	97	43%	0.433	52%	0.522	S	S	.	.	H	α-helix	trans	-61	-36.9	178.2	-64.9	2.9	0	0	0	111.8	N249 K255 N257	N249-N253 WeakPolarHBondContact O-CB 3.47Å; N249-N253 PolarHBondContact O-N 3.36Å; N249-N253 PolarHBondContact O-OD1 3.26Å; N253-K255 VanDerWaalsContact C-N 3.34Å; N253-N257 WeakPolarHBondContact O-CB 3.36Å; N253-N257 VanDerWaalsContact O-CG 3.28Å; N253-N257 PolarHBondContact O-N 3.29Å; N253-N257 PolarHBondContact O-ND2 3.08Å
254	S	81.1	Confident	75.7	Confident	63 Å²	63	104.3 Å²	104.3	44%	0.441	56%	0.555	S	S	.	*	H	α-helix	trans	-68.1	-31.6	175.3	-62.5	0	0	0	0	113.1	N250 N251 T252 K258	N250-S254 VanDerWaalsContact O-CB 3.32Å; N250-S254 WeakPolarHBondContact O-CB 3.41Å; N250-S254 PolarHBondContact O-N 2.84Å; N250-S254 PolarHBondContact O-OG 3.28Å; N251-S254 PolarHBondContact O-N 3.49Å; T252-S254 VanDerWaalsContact C-N 3.27Å; T252-S254 PolarHBondContact O-N 3.45Å; S254-K258 WeakPolarHBondContact O-CG 3.4Å; S254-K258 PolarHBondContact O-N 3.38Å
255	K	80.1	Confident	73.8	Confident	158 Å²	158	102 Å²	102	69%	0.687	55%	0.549	S	S	*	.	H	α-helix	trans	-74.6	-43.6	174.3	-76.4	-179	179	-175.5	0	111.2	N251 T252 N253 K258 L259	N251-K255 WeakPolarHBondContact O-CG 3.45Å; N251-K255 PolarHBondContact O-N 2.88Å; T252-K255 WeakPolarHBondContact O-CA 3.47Å; T252-K255 WeakPolarHBondContact O-CB 3.3Å; T252-K255 PolarHBondContact O-N 3.38Å; N253-K255 VanDerWaalsContact C-N 3.34Å; K255-K258 PolarHBondContact O-N 2.58Å; K255-L259 WeakPolarHBondContact O-CB 3.28Å; K255-L259 PolarHBondContact O-N 2.87Å
256	E	76.6	Confident	71.6	Confident	117 Å²	117	107.1 Å²	107.1	55%	0.547	57%	0.574	S	S	.	*	H	α-helix	trans	-59.6	-47.7	175.3	-74.5	178.1	170.1	0	0	111.4	T252 K258 L259 S260	T252-E256 PolarHBondContact O-N 3.01Å; E256-K258 VanDerWaalsContact C-N 3.27Å; E256-K258 PolarHBondContact O-N 3.45Å; E256-L259 PolarHBondContact O-N 3.32Å; E256-S260 PolarHBondContact O-N 3.31Å; E256-S260 PolarHBondContact O-OG 2.85Å
257	N	77.8	Confident	69.3	Low	120 Å²	120	108.4 Å²	108.4	64%	0.642	59%	0.589	S	S	*	*	H	α-helix	trans	-60	-35	176.4	-74.3	-14.5	0	0	0	113.1	N253 G261	N253-N257 WeakPolarHBondContact O-CB 3.36Å; N253-N257 VanDerWaalsContact O-CG 3.28Å; N253-N257 PolarHBondContact O-N 3.29Å; N253-N257 PolarHBondContact O-ND2 3.08Å; N257-G261 PolarHBondContact O-N 3.27Å
258	K	76.1	Confident	66.9	Low	118 Å²	118	110.9 Å²	110.9	51%	0.513	60%	0.6	S	S	.	*	H	α-helix	trans	-71.8	-36.3	173.8	-75.8	176.8	-178.6	177.6	0	112.2	S254 K255 E256 N262	S254-K258 WeakPolarHBondContact O-CG 3.4Å; S254-K258 PolarHBondContact O-N 3.38Å; K255-K258 PolarHBondContact O-N 2.58Å; E256-K258 VanDerWaalsContact C-N 3.27Å; E256-K258 PolarHBondContact O-N 3.45Å; K258-N262 PolarHBondContact O-N 2.84Å; K258-N262 VanDerWaalsContact O-N 3.11Å
259	L	73.1	Confident	64.3	Low	120 Å²	120	111.8 Å²	111.8	63%	0.628	61%	0.613	S	S	*	*	H	α-helix	trans	-70.5	-48.2	178.6	-168.7	67.3	0	0	0	110.8	K255 E256 G261 N262 T263	K255-L259 WeakPolarHBondContact O-CB 3.28Å; K255-L259 PolarHBondContact O-N 2.87Å; E256-L259 PolarHBondContact O-N 3.32Å; L259-G261 VanDerWaalsContact C-N 3.3Å; L259-G261 PolarHBondContact O-N 2.91Å; L259-N262 PolarHBondContact O-N 3.26Å; L259-N262 VanDerWaalsContact O-N 3.12Å; L259-T263 PolarHBondContact O-N 3.21Å; L259-T263 PolarHBondContact O-OG1 2.8Å
260	S	69.7	Low	61.5	Low	80 Å²	80	116.4 Å²	116.4	56%	0.559	63%	0.631	S	S	*	*	H	α-helix	trans	-61.4	-37.1	174	-58.9	0	0	0	0	112.3	E256 N262 F264	E256-S260 PolarHBondContact O-N 3.31Å; E256-S260 PolarHBondContact O-OG 2.85Å; S260-N262 VanDerWaalsContact C-N 3.33Å; S260-N262 PolarHBondContact O-N 2.85Å; S260-F264 PolarHBondContact O-N 3.48Å
261	G	60.9	Low	58.9	Low	47 Å²	47	121.3 Å²	121.3	49%	0.485	65%	0.647	S	S	.	*	H	α-helix	trans	-65.2	-32.3	173.9	0	0	0	0	0	113.9	N257 L259	N257-G261 PolarHBondContact O-N 3.27Å; L259-G261 VanDerWaalsContact C-N 3.3Å; L259-G261 PolarHBondContact O-N 2.91Å
262	N	55.4	Low	56.1	Low	134 Å²	134	125.4 Å²	125.4	72%	0.717	66%	0.664	S	S	*	*	H	α-helix	trans	-80.4	-32.7	177.8	-79.5	3.6	0	0	0	113	K258 L259 S260 F264	K258-N262 PolarHBondContact O-N 2.84Å; K258-N262 VanDerWaalsContact O-N 3.11Å; L259-N262 PolarHBondContact O-N 3.26Å; L259-N262 VanDerWaalsContact O-N 3.12Å; S260-N262 VanDerWaalsContact C-N 3.33Å; S260-N262 PolarHBondContact O-N 2.85Å; N262-F264 VanDerWaalsContact C-N 3.32Å
263	T	53.6	Low	53.3	Low	122 Å²	122	131.9 Å²	131.9	75%	0.748	68%	0.682	S	S	*	*	H	α-helix	trans	-72.6	-25.5	177.2	-51.6	0	0	0	0	112.4	L259	L259-T263 PolarHBondContact O-N 3.21Å; L259-T263 PolarHBondContact O-OG1 2.8Å
264	F	49.1	Very low	50.6	Low	202 Å²	202	135 Å²	135	89%	0.886	70%	0.697	S	S	*	*	T	Hydrogen-bonded Turn	trans	-97.1	12.8	-179.3	-154.2	-102.9	0	0	0	114.5	S260 N262	S260-F264 PolarHBondContact O-N 3.48Å; N262-F264 VanDerWaalsContact C-N 3.32Å
265	G	42.5	Very low	47.8	Very low	44 Å²	44	139.9 Å²	139.9	45%	0.454	71%	0.712	S	S	.	*			trans	-146.9	55	-166	0	0	0	0	0	117	S267	G265-S267 PolarHBondContact O-N 3.21Å
266	I	38	Very low	45.4	Very low	175 Å²	175	137.9 Å²	137.9	90%	0.897	71%	0.713	S	S	*	*			trans	-73.9	77.2	146.8	-59.8	177.5	0	0	0	106.5
267	S	35.6	Very low	43	Very low	104 Å²	104	138.1 Å²	138.1	73%	0.727	72%	0.719	S	S	*	*	S	Bend	trans	-168.5	97	160.8	-87	0	0	0	0	110.5	G265	G265-S267 PolarHBondContact O-N 3.21Å
268	K	29.8	Very low	40.7	Very low	196 Å²	196	139.8 Å²	139.8	85%	0.852	73%	0.727	S	S	*	*			trans	58.9	118.4	142.5	-65	-177.9	176.4	176.8	0	120.2
269	T	28.3	Very low	38.3	Very low	134 Å²	134	140 Å²	140	82%	0.822	74%	0.739	S	S	*	*			trans	82.2	98.5	137	29.7	0	0	0	0	121.1
270	H	27.4	Very low	36.2	Very low	178 Å²	178	139.4 Å²	139.4	82%	0.824	75%	0.745	S	S	*	*				44.7	87	126.5	-135.6	42.1	0	0	0	117.7
271	K	28.2	Very low	34.1	Very low	205 Å²	205	144.6 Å²	144.6	89%	0.891	76%	0.76	S	S	*	*			trans	-119.4	115.6	149.2	-106.2	176.8	178.3	172.9	0	108.5	R273	K271-R273 PolarHBondContact O-N 3.03Å
272	Q	26.7	Very low	32.5	Very low	176 Å²	176	150.2 Å²	150.2	82%	0.822	78%	0.779	S	S	*	*			trans	-43.3	119	-180	-79.6	164.4	-36.6	0	0	111.6	I274	Q272-I274 PolarHBondContact O-N 3.36Å
273	R	25.1	Very low	31.2	Very low	196 Å²	196	148.2 Å²	148.2	74%	0.74	78%	0.775	S	S	*	*			trans	-77.7	102.4	169.4	-176.1	-174.2	-109.4	-166.9	0.6	107	K271 Q275	K271-R273 PolarHBondContact O-N 3.03Å; R273-Q275 PolarHBondContact O-N 3.49Å
274	I	26.8	Very low	30	Very low	146 Å²	146	148.2 Å²	148.2	75%	0.749	78%	0.779	S	S	*	*			trans	-63.5	106.8	164.5	-62.5	173.4	0	0	0	106.7	Q272 V276	Q272-I274 PolarHBondContact O-N 3.36Å; I274-V276 HydrophobicContact CG2-CG2 4.22Å; I274-V276 PolarHBondContact O-N 2.95Å
275	Q	23.4	Very low	29.1	Very low	165 Å²	165	143.6 Å²	143.6	77%	0.771	77%	0.767	S	S	*	*			trans	-68.7	112.9	165.5	-117.4	172.2	-34.4	0	0	106.9	R273	R273-Q275 PolarHBondContact O-N 3.49Å
276	V	29.6	Very low	28.4	Very low	116 Å²	116	148.7 Å²	148.7	70%	0.703	78%	0.784	S	S	*	*			trans	-91.4	99.6	168.7	178.9	0	0	0	0	105.8	I274 D278	I274-V276 HydrophobicContact CG2-CG2 4.22Å; I274-V276 PolarHBondContact O-N 2.95Å; V276-D278 PolarHBondContact O-N 3.39Å
277	D	24.7	Very low	28.2	Very low	123 Å²	123	143.7 Å²	143.7	66%	0.658	77%	0.769	S	S	*	*			trans	-67	119.1	166.5	-83.8	-29.2	0	0	0	109	T279	D277-T279 PolarHBondContact O-N 3.28Å
278	D	30.2	Very low	28	Very low	154 Å²	154	145.8 Å²	145.8	82%	0.824	77%	0.771	S	S	*	*	S	Bend	trans	-73.7	52.2	175.7	-94.1	-28.5	0	0	0	111.1	V276	V276-D278 PolarHBondContact O-N 3.39Å
279	T	26.6	Very low	28	Very low	123 Å²	123	143.4 Å²	143.4	76%	0.755	77%	0.767	S	S	*	*			trans	-164.9	78.3	171.1	36.1	0	0	0	0	112.5	D277	D277-T279 PolarHBondContact O-N 3.28Å
280	S	28.6	Very low	28.2	Very low	108 Å²	108	142.4 Å²	142.4	76%	0.755	76%	0.757	S	S	*	*			trans	-167.9	107.9	151.1	14.6	0	0	0	0	113.2
281	Q	26.5	Very low	28.6	Very low	189 Å²	189	142.2 Å²	142.2	88%	0.883	75%	0.754	S	S	*	*			trans	50.8	96.2	139.9	-64.6	176.9	-8.6	0	0	118.1	S283	Q281-S283 PolarHBondContact O-N 3.22Å
282	D	26.4	Very low	28.6	Very low	164 Å²	164	135.6 Å²	135.6	88%	0.877	74%	0.744	S	S	*	*			trans	-51.6	91.5	155.1	-71.5	-44.6	0	0	0	111
283	S	28.8	Very low	29	Very low	92 Å²	92	134 Å²	134	64%	0.643	74%	0.737	S	S	*	*			trans	-91.5	109.2	161.4	178.9	0	0	0	0	109	Q281 T285	Q281-S283 PolarHBondContact O-N 3.22Å; S283-T285 VanDerWaalsContact C-N 3.35Å; S283-T285 PolarHBondContact O-N 2.8Å; S283-T285 PolarHBondContact OG-OG1 3.36Å
284	C	28.7	Very low	29.4	Very low	122 Å²	122	131.2 Å²	131.2	82%	0.824	73%	0.732	S	S	*	*			trans	-69.9	87.9	168.8	-68.9	0	0	0	0	110.2
285	T	29.3	Very low	29.7	Very low	105 Å²	105	132.7 Å²	132.7	64%	0.644	73%	0.733	S	S	*	*			trans	-122.1	-10	168	12	0	0	0	0	115	S283 A287	S283-T285 VanDerWaalsContact C-N 3.35Å; S283-T285 PolarHBondContact O-N 2.8Å; S283-T285 PolarHBondContact OG-OG1 3.36Å; T285-A287 PolarHBondContact O-N 2.98Å
286	D	28.6	Very low	30	Very low	151 Å²	151	131.9 Å²	131.9	81%	0.807	73%	0.733	S	S	*	*	T	Hydrogen-bonded Turn	trans	-94.8	11.8	179.4	-64.9	-17.7	0	0	0	114.6
287	A	32.6	Very low	30.1	Very low	71 Å²	71	131 Å²	131	59%	0.587	72%	0.724	S	S	*	*	T	Hydrogen-bonded Turn	trans	-86	-5.1	-173.7	0	0	0	0	0	115.2	T285	T285-A287 PolarHBondContact O-N 2.98Å
288	I	31.5	Very low	30.8	Very low	147 Å²	147	129.8 Å²	129.8	75%	0.754	72%	0.721	S	S	*	*	S	Bend	trans	-86.2	-28.4	-177.2	-64.3	179.5	0	0	0	112.5	N290	I288-N290 PolarHBondContact O-N 2.83Å
289	N	29	Very low	31.1	Very low	146 Å²	146	129.7 Å²	129.7	78%	0.781	72%	0.716	S	S	*	*	T	Hydrogen-bonded Turn	trans	-86.7	-5.5	-170.9	-68.8	-7.9	0	0	0	115.8
290	N	32.8	Very low	31.5	Very low	114 Å²	114	127.2 Å²	127.2	61%	0.61	70%	0.703	S	S	*	*	T	Hydrogen-bonded Turn	trans	-114.3	1.3	-176.7	-78	-30.1	0	0	0	115.3	I288 G292	I288-N290 PolarHBondContact O-N 2.83Å; N290-G292 VanDerWaalsContact C-N 3.32Å
291	F	35.5	Very low	31.9	Very low	174 Å²	174	126.3 Å²	126.3	76%	0.763	69%	0.69	S	S	*	*	T	Hydrogen-bonded Turn	trans	-78.5	-18.5	176.4	-132	-89.5	0	0	0	112.7
292	G	30.2	Very low	32.5	Very low	66 Å²	66	123.5 Å²	123.5	68%	0.68	68%	0.68	S	S	*	*	T	Hydrogen-bonded Turn	trans	-71.5	-39.1	179.6	0	0	0	0	0	114.4	N290	N290-G292 VanDerWaalsContact C-N 3.32Å
293	E	33.9	Very low	32.8	Very low	141 Å²	141	123.2 Å²	123.2	66%	0.659	67%	0.674	S	S	*	*	T	Hydrogen-bonded Turn	trans	-83.9	-18.8	-173.3	-80.9	-172.4	142.4	0	0	114.8
294	Q	33.5	Very low	32.9	Very low	139 Å²	139	122.6 Å²	122.6	65%	0.65	67%	0.669	S	S	*	*	H	α-helix	trans	-79.6	-19.3	-176.5	-100.6	178	0.3	0	0	114.5	L296 T298	Q294-L296 VanDerWaalsContact C-N 3.33Å; Q294-T298 PolarHBondContact O-OG1 3.45Å
295	K	32.5	Very low	33.2	Very low	176 Å²	176	122.9 Å²	122.9	77%	0.765	66%	0.661	S	S	*	*	H	α-helix	trans	-74.4	-24.7	179.5	-155	177.4	179.6	-171.2	0	112.5
296	L	30.8	Very low	33.3	Very low	149 Å²	149	125.9 Å²	125.9	78%	0.78	67%	0.668	S	S	*	*	H	α-helix	trans	-87.2	-27	-179.3	-137.8	89.7	0	0	0	113.8	Q294	Q294-L296 VanDerWaalsContact C-N 3.33Å
297	I	32.4	Very low	33.3	Very low	97 Å²	97	126.9 Å²	126.9	50%	0.497	67%	0.668	S	S	.	*	H	α-helix	trans	-92.7	-15.3	-171	-59.1	171.9	0	0	0	112.8	S300 N301	I297-S300 PolarHBondContact O-OG 2.79Å; I297-N301 PolarHBondContact O-ND2 3.12Å
298	T	37.9	Very low	33	Very low	98 Å²	98	130.7 Å²	130.7	60%	0.601	68%	0.678	S	S	*	*	H	α-helix	trans	-83.5	-24.1	-176.3	-47.4	0	0	0	0	112.8	Q294	Q294-T298 PolarHBondContact O-OG1 3.45Å
299	E	36.3	Very low	32.8	Very low	152 Å²	152	132.9 Å²	132.9	71%	0.71	69%	0.685	S	S	*	*	H	α-helix	trans	-77.8	-33.1	178.7	-75.6	177.8	173.8	0	0	112.7
300	S	36.5	Very low	32.6	Very low	70 Å²	70	133.7 Å²	133.7	49%	0.49	69%	0.689	S	S	.	*	H	α-helix	trans	-72.7	-34	-179.8	67.5	0	0	0	0	113.7	I297	I297-S300 PolarHBondContact O-OG 2.79Å
301	N	36.7	Very low	32.1	Very low	90 Å²	90	134.6 Å²	134.6	48%	0.481	70%	0.698	S	S	.	*	H	α-helix	trans	-82.3	-10.1	-176.6	-75.7	-43	0	0	0	114.1	I297 I305	I297-N301 PolarHBondContact O-ND2 3.12Å; N301-I305 WeakPolarHBondContact O-CD1 3.27Å; N301-I305 WeakPolarHBondContact O-CG1 3.23Å
302	L	38.9	Very low	31.4	Very low	129 Å²	129	133.8 Å²	133.8	68%	0.675	70%	0.7	S	S	*	*	H	α-helix	trans	-84.7	-27.4	176.7	-156.4	70.1	0	0	0	111.9
303	Q	31.6	Very low	31.1	Very low	159 Å²	159	136.2 Å²	136.2	74%	0.743	70%	0.704	S	S	*	*	H	α-helix	trans	-77.1	-30.7	176.7	-78.4	176.4	-22	0	0	113	I305	Q303-I305 PolarHBondContact O-N 3.26Å
304	S	31.8	Very low	30.6	Very low	78 Å²	78	138 Å²	138	55%	0.545	71%	0.712	S	S	.	*	T	Hydrogen-bonded Turn	trans	-83.1	-7.6	-178.4	65.7	0	0	0	0	115.2
305	I	34.3	Very low	30.1	Very low	129 Å²	129	141.3 Å²	141.3	66%	0.662	73%	0.725	S	S	*	*	T	Hydrogen-bonded Turn	trans	-88.5	-12.9	177.5	-65.9	173.4	0	0	0	111.2	N301 Q303	N301-I305 WeakPolarHBondContact O-CD1 3.27Å; N301-I305 WeakPolarHBondContact O-CG1 3.23Å; Q303-I305 PolarHBondContact O-N 3.26Å
306	Q	31.8	Very low	29.5	Very low	167 Å²	167	141.2 Å²	141.2	78%	0.78	73%	0.729	S	S	*	*	S	Bend	trans	-90	-2.5	-169.8	-147	155.6	-20.9	0	0	115
307	E	29.6	Very low	29.1	Very low	172 Å²	172	140 Å²	140	80%	0.804	73%	0.728	S	S	*	*	S	Bend	trans	-109.9	-1.7	-176.6	-80	-175.7	158.6	0	0	116.4
308	N	26.7	Very low	28.6	Very low	152 Å²	152	142 Å²	142	81%	0.813	74%	0.74	S	S	*	*			trans	-121.9	23.6	-175.8	-81.5	-15.3	0	0	0	116.1	L310	N308-L310 PolarHBondContact O-N 3.17Å
309	E	25.8	Very low	27.9	Very low	192 Å²	192	148.1 Å²	148.1	90%	0.897	75%	0.751	S	S	*	*			trans	-91.3	70.5	163.3	-87.6	-172.8	158.6	0	0	110.8
310	L	24.9	Very low	27.2	Very low	163 Å²	163	148.3 Å²	148.3	85%	0.853	76%	0.758	S	S	*	*			trans	-153	57.7	159.7	-154.2	87.6	0	0	0	113	N308	N308-L310 PolarHBondContact O-N 3.17Å
311	T	22.1	Very low	26.6	Very low	133 Å²	133	153.9 Å²	153.9	82%	0.816	78%	0.776	S	S	*	*			trans	-158.4	110.1	147.6	-21.2	0	0	0	0	110.9
312	I	20.8	Very low	25.9	Very low	157 Å²	157	155.8 Å²	155.8	81%	0.805	79%	0.79	S	S	*	*			trans	-87.5	125.9	163.8	-63.8	167.2	0	0	0	106.2
313	P	24.6	Very low	24.9	Very low	118 Å²	118	158.3 Å²	158.3	77%	0.766	80%	0.799	S	S	*	*			trans	-115.6	109.1	146.4	11.7	7.7	0	0	0	109.3	K315	P313-K315 PolarHBondContact O-N 3.49Å
314	E	23	Very low	24.4	Very low	177 Å²	177	155.7 Å²	155.7	83%	0.827	80%	0.798	S	S	*	*			trans	-56.4	122.8	151.5	-86.7	174.8	137.2	0	0	109.3
315	K	23.3	Very low	24	Very low	209 Å²	209	159.2 Å²	159.2	91%	0.909	82%	0.817	S	S	*	*				-161.8	121.8	126.7	-107.2	170.3	-174.4	-177.8	0	111.1	P313	P313-K315 PolarHBondContact O-N 3.49Å
316	M	19.8	Very low	23.3	Very low	174 Å²	174	158.4 Å²	158.4	86%	0.857	82%	0.822	S	S	*	*			trans	-63.5	148.5	168.3	-79.5	174.3	155.9	0	0	111.6
317	V	22	Very low	22.8	Very low	123 Å²	123	161.5 Å²	161.5	75%	0.745	83%	0.827	S	S	*	*			trans	62	123.5	139.8	-177.4	0	0	0	0	114.8
318	D	21.6	Very low	22.4	Very low	140 Å²	140	162.4 Å²	162.4	75%	0.749	83%	0.828	S	S	*	*				-172.8	172.6	50.4	-139.9	-19.3	0	0	0	110.9
319	R	24.1	Very low	22.3	Very low	226 Å²	226	162.2 Å²	162.2	85%	0.853	83%	0.827	S	S	*	*			trans	89.1	113.1	154.6	-78.1	-179.6	176.5	-179.5	-2	122.2
320	D	21.1	Very low	22.2	Very low	157 Å²	157	159 Å²	159	84%	0.84	82%	0.82	S	S	*	*			trans	-42	137.6	147.7	-55.5	-67.9	0	0	0	113.9
321	E	23.5	Very low	22.2	Very low	186 Å²	186	159.4 Å²	159.4	87%	0.869	82%	0.818	S	S	*	*			trans	-159.6	106.3	143.4	-117.9	171.8	-168.5	0	0	112.5
322	V	22.4	Very low	22.5	Very low	130 Å²	130	159.9 Å²	159.9	79%	0.788	82%	0.815	S	S	*	*				44.8	102.5	127.7	-173.1	0	0	0	0	119.2
323	Q	19.1	Very low	22.8	Very low	183 Å²	183	159 Å²	159	86%	0.855	81%	0.812	S	S	*	*			trans	-25.9	117.8	135.1	-171.8	174.3	23.7	0	0	115.7
324	S	20.5	Very low	22.9	Very low	103 Å²	103	160.2 Å²	160.2	72%	0.72	81%	0.812	S	S	*	*			trans	164.7	119	140.2	-74.1	0	0	0	0	111.5
325	T	22.3	Very low	23.4	Very low	153 Å²	153	159.4 Å²	159.4	94%	0.939	81%	0.814	S	S	*	*				-175.7	122.2	124.7	25.4	0	0	0	0	110.4
326	S	20.3	Very low	23.6	Very low	111 Å²	111	156.7 Å²	156.7	78%	0.776	81%	0.809	S	S	*	*			trans	-96.8	129	167.1	175.4	0	0	0	0	107.6
327	R	21	Very low	24.3	Very low	232 Å²	232	156 Å²	156	88%	0.875	81%	0.808	S	S	*	*			trans	164.3	123.1	130.6	-97.6	174.3	168.2	157.2	-3.7	113.2
328	K	20.8	Very low	24.6	Very low	191 Å²	191	156.7 Å²	156.7	83%	0.83	81%	0.808	S	S	*	*			trans	37	115	132.4	-91.5	-179.9	168.6	-178.4	0	118.6
329	N	25.1	Very low	24.9	Very low	149 Å²	149	156.7 Å²	156.7	80%	0.797	81%	0.808	S	S	*	*			trans	-155.5	105.9	136.3	-93.1	-13.9	0	0	0	106.1
330	T	24.2	Very low	25.2	Very low	123 Å²	123	153.3 Å²	153.3	76%	0.755	81%	0.807	S	S	*	*				100.6	125.7	95.2	40.1	0	0	0	0	111.1
331	H	24.2	Very low	25.6	Very low	173 Å²	173	152.6 Å²	152.6	80%	0.801	80%	0.803	S	S	*	*			trans	-3.1	126.2	158.9	-76.8	-78.9	0	0	0	117.4
332	D	29.5	Very low	26.1	Very low	143 Å²	143	149.3 Å²	149.3	77%	0.765	80%	0.801	S	S	*	*				-163.4	133	106.5	-93.7	-26.6	0	0	0	112.9
333	N	27.4	Very low	27	Very low	138 Å²	138	146.5 Å²	146.5	74%	0.738	79%	0.787	S	S	*	*			trans	40.9	117	152.6	-62.6	-34.2	0	0	0	122.5	D335	N333-D335 PolarHBondContact O-N 2.9Å
334	N	26.1	Very low	28.2	Very low	144 Å²	144	144.6 Å²	144.6	77%	0.77	78%	0.781	S	S	*	*			trans	-6.2	112.7	133.8	-75.2	-19.5	0	0	0	115.3
335	D	32.9	Very low	28.9	Very low	160 Å²	160	149 Å²	149	86%	0.856	79%	0.787	S	S	*	*			trans	-131.3	113.3	133.7	-88.9	-39.5	0	0	0	108.6	N333 D337	N333-D335 PolarHBondContact O-N 2.9Å; D335-D337 PolarHBondContact O-N 3.28Å; D335-D337 VanDerWaalsContact O-N 3.16Å
336	N	28.2	Very low	30.2	Very low	152 Å²	152	146.2 Å²	146.2	81%	0.813	77%	0.77	S	S	*	*			trans	-69.3	95.1	166.7	-88.4	-37.6	0	0	0	107.8
337	D	33.3	Very low	31.3	Very low	158 Å²	158	148.5 Å²	148.5	85%	0.845	77%	0.766	S	S	*	*			trans	-112.1	95.1	157.4	-95.8	-25.6	0	0	0	110.2	D335	D335-D337 PolarHBondContact O-N 3.28Å; D335-D337 VanDerWaalsContact O-N 3.16Å
338	N	28.2	Very low	32.7	Very low	139 Å²	139	145.2 Å²	145.2	74%	0.743	76%	0.758	S	S	*	*			trans	-50.7	147.4	156.6	-90.9	-40.6	0	0	0	110.6
339	N	29.6	Very low	34.7	Very low	139 Å²	139	139.2 Å²	139.2	74%	0.743	74%	0.739	S	S	*	*			trans	64	103.9	163.3	-66	-27.6	0	0	0	115.7
340	N	29.1	Very low	37.3	Very low	155 Å²	155	136.3 Å²	136.3	83%	0.829	72%	0.722	S	S	*	*				-159.3	122.2	113	-93.2	-37.6	0	0	0	112	S342	N340-S342 PolarHBondContact O-N 3.27Å
341	N	29.5	Very low	40.1	Very low	142 Å²	142	135.9 Å²	135.9	76%	0.759	72%	0.715	S	S	*	*			trans	-22.3	93	161.3	-71.4	-45	0	0	0	114.3	S343	N341-S343 PolarHBondContact O-N 3.26Å
342	S	34	Very low	42.8	Very low	117 Å²	117	134.2 Å²	134.2	82%	0.818	71%	0.708	S	S	*	*			trans	-86	30.3	158.2	63.1	0	0	0	0	111.1	N340	N340-S342 PolarHBondContact O-N 3.27Å
343	S	41.9	Very low	45.4	Very low	71 Å²	71	132.3 Å²	132.3	50%	0.497	70%	0.698	S	S	.	*			trans	-92.4	92.9	166.7	46.8	0	0	0	0	107.8	N341	N341-S343 PolarHBondContact O-N 3.26Å
344	I	43.2	Very low	48.1	Very low	144 Å²	144	133.2 Å²	133.2	74%	0.738	69%	0.691	S	S	*	*	S	Bend	trans	-178	-21.3	150.7	-91.8	147.9	0	0	0	113.5	T346	I344-T346 PolarHBondContact O-N 3.38Å
345	K	36	Very low	50.9	Low	194 Å²	194	129.8 Å²	129.8	84%	0.843	68%	0.678	S	S	*	*	T	Hydrogen-bonded Turn	trans	-78.3	-13.9	179.3	-73.9	-174.7	179.5	177.4	0	115.4	P349	K345-P349 WeakPolarHBondContact O-CD 3.38Å
346	T	48.6	Very low	53.4	Low	95 Å²	95	127.2 Å²	127.2	58%	0.583	66%	0.659	S	S	*	*	T	Hydrogen-bonded Turn	trans	-82.4	-21.3	-178.4	32.5	0	0	0	0	115.1	I344 I350	I344-T346 PolarHBondContact O-N 3.38Å; T346-I350 VanDerWaalsContact O-CD1 3.25Å; T346-I350 WeakPolarHBondContact O-CD1 2.96Å; T346-I350 WeakPolarHBondContact O-CG1 3.25Å
347	K	44	Very low	56.1	Low	160 Å²	160	123.2 Å²	123.2	70%	0.696	64%	0.635	S	S	*	*	H	α-helix	trans	-77.4	-34.6	-176.3	-70.8	-175.4	180	177.8	0	114	L351	K347-L351 WeakPolarHBondContact O-CG 3.34Å; K347-L351 PolarHBondContact O-N 3.38Å
348	K	51.4	Low	58.6	Low	162 Å²	162	124.9 Å²	124.9	70%	0.704	63%	0.63	S	S	*	*	H	α-helix	trans	-62	-48.5	-179.2	-75.9	-173.6	178	-178.7	0	114.6	I350 L351 Q352	K348-I350 VanDerWaalsContact C-N 3.33Å; K348-I350 PolarHBondContact O-N 3.22Å; K348-L351 PolarHBondContact O-N 2.93Å; K348-Q352 PolarHBondContact O-N 3.35Å
349	P	62.7	Low	61.3	Low	66 Å²	66	123.2 Å²	123.2	43%	0.429	61%	0.613	S	S	.	*	H	α-helix	trans	-62.5	-39.3	179	19.4	-29.4	0	0	0	112.3	K345 L351 Q352 D353	K345-P349 WeakPolarHBondContact O-CD 3.38Å; P349-L351 VanDerWaalsContact C-N 3.33Å; P349-L351 PolarHBondContact O-N 2.98Å; P349-Q352 PolarHBondContact O-N 3.01Å; P349-D353 PolarHBondContact O-N 3.49Å
350	I	78.4	Confident	64	Low	87 Å²	87	119.3 Å²	119.3	45%	0.446	59%	0.59	S	S	.	*	H	α-helix	trans	-61.6	-40.1	179	-60.3	170.6	0	0	0	111.7	T346 K348 R354	T346-I350 VanDerWaalsContact O-CD1 3.25Å; T346-I350 WeakPolarHBondContact O-CD1 2.96Å; T346-I350 WeakPolarHBondContact O-CG1 3.25Å; K348-I350 VanDerWaalsContact C-N 3.33Å; K348-I350 PolarHBondContact O-N 3.22Å; I350-R354 WeakPolarHBondContact O-CB 3.28Å; I350-R354 VanDerWaalsContact O-CG 3.26Å; I350-R354 WeakPolarHBondContact O-CG 3.49Å; I350-R354 PolarHBondContact O-N 2.94Å
351	L	82.8	Confident	66.7	Low	114 Å²	114	114.9 Å²	114.9	60%	0.597	57%	0.567	S	S	*	*	H	α-helix	trans	-68.4	-42.5	178.2	-70.5	175.6	0	0	0	112.2	K347 K348 P349 R354 S355	K347-L351 WeakPolarHBondContact O-CG 3.34Å; K347-L351 PolarHBondContact O-N 3.38Å; K348-L351 PolarHBondContact O-N 2.93Å; P349-L351 VanDerWaalsContact C-N 3.33Å; P349-L351 PolarHBondContact O-N 2.98Å; L351-R354 PolarHBondContact O-N 3.36Å; L351-S355 PolarHBondContact O-N 3Å
352	Q	82.1	Confident	69.4	Low	139 Å²	139	110.9 Å²	110.9	65%	0.65	55%	0.553	S	S	*	*	H	α-helix	trans	-61.6	-45.1	176.1	-71.7	-173.1	-1.1	0	0	111.1	K348 P349 R354 S355 K356	K348-Q352 PolarHBondContact O-N 3.35Å; P349-Q352 PolarHBondContact O-N 3.01Å; Q352-R354 PolarHBondContact O-N 3.44Å; Q352-S355 PolarHBondContact O-N 2.65Å; Q352-S355 PolarHBondContact O-OG 3.2Å; Q352-K356 WeakPolarHBondContact O-CB 3.28Å; Q352-K356 PolarHBondContact O-N 2.83Å
353	D	82.9	Confident	71.9	Confident	103 Å²	103	108.2 Å²	108.2	55%	0.551	53%	0.528	S	S	*	.	H	α-helix	trans	-61.9	-43.1	176.7	-73.7	-28.1	0	0	0	112.2	P349 S355 K356 Q357	P349-D353 PolarHBondContact O-N 3.49Å; D353-S355 PolarHBondContact O-N 3.28Å; D353-K356 PolarHBondContact O-N 3.42Å; D353-Q357 VanDerWaalsContact O-CB 3.32Å; D353-Q357 WeakPolarHBondContact O-CB 3.29Å; D353-Q357 PolarHBondContact O-N 2.67Å
354	R	86.2	Confident	74.1	Confident	157 Å²	157	108.4 Å²	108.4	59%	0.592	52%	0.518	S	S	*	.	H	α-helix	trans	-60.5	-43.6	174.7	-76.8	177.5	-179.7	-166.2	0.5	112.2	I350 L351 Q352 Q357 R358	I350-R354 WeakPolarHBondContact O-CB 3.28Å; I350-R354 VanDerWaalsContact O-CG 3.26Å; I350-R354 WeakPolarHBondContact O-CG 3.49Å; I350-R354 PolarHBondContact O-N 2.94Å; L351-R354 PolarHBondContact O-N 3.36Å; Q352-R354 PolarHBondContact O-N 3.44Å; R354-Q357 PolarHBondContact O-N 3.49Å; R354-R358 WeakPolarHBondContact O-CG 3.18Å; R354-R358 PolarHBondContact O-N 2.72Å
355	S	83.9	Confident	76.3	Confident	71 Å²	71	108.4 Å²	108.4	50%	0.497	51%	0.512	S	S	.	.	H	α-helix	trans	-65.2	-41.9	178.1	74.6	0	0	0	0	112.4	L351 Q352 D353 Q357 R358 R359	L351-S355 PolarHBondContact O-N 3Å; Q352-S355 PolarHBondContact O-N 2.65Å; Q352-S355 PolarHBondContact O-OG 3.2Å; D353-S355 PolarHBondContact O-N 3.28Å; S355-Q357 VanDerWaalsContact C-N 3.34Å; S355-R358 PolarHBondContact O-N 3.11Å; S355-R359 WeakPolarHBondContact O-CB 3.22Å; S355-R359 PolarHBondContact O-N 3.49Å
356	K	84.7	Confident	78.9	Confident	107 Å²	107	99.8 Å²	99.8	47%	0.465	48%	0.476	S	S	.	.	H	α-helix	trans	-62.4	-43.1	175.2	-174.4	179.2	178.6	-178	0	110.5	Q352 D353 R359 Q360	Q352-K356 WeakPolarHBondContact O-CB 3.28Å; Q352-K356 PolarHBondContact O-N 2.83Å; D353-K356 PolarHBondContact O-N 3.42Å; K356-R359 PolarHBondContact O-N 3.16Å; K356-Q360 WeakPolarHBondContact O-CB 3.4Å; K356-Q360 VanDerWaalsContact O-CG 3.31Å; K356-Q360 WeakPolarHBondContact O-CG 3.09Å; K356-Q360 PolarHBondContact O-N 3.5Å
357	Q	85.3	Confident	80.9	Confident	68 Å²	68	95.3 Å²	95.3	32%	0.318	45%	0.448	S	S	.	.	H	α-helix	trans	-62.7	-46.7	175.8	-171.6	64.9	23.3	0	0	112	D353 R354 S355 R359 Q360 N361	D353-Q357 VanDerWaalsContact O-CB 3.32Å; D353-Q357 WeakPolarHBondContact O-CB 3.29Å; D353-Q357 PolarHBondContact O-N 2.67Å; R354-Q357 PolarHBondContact O-N 3.49Å; S355-Q357 VanDerWaalsContact C-N 3.34Å; Q357-R359 VanDerWaalsContact C-N 3.32Å; Q357-R359 PolarHBondContact O-N 2.85Å; Q357-Q360 PolarHBondContact O-N 2.96Å; Q357-N361 PolarHBondContact NE2-OD1 3.45Å; Q357-N361 WeakPolarHBondContact O-CB 3.32Å; Q357-N361 VanDerWaalsContact O-CG 3.27Å; Q357-N361 PolarHBondContact O-N 3.25Å
358	R	86.9	Confident	83.1	Confident	193 Å²	193	91 Å²	91	73%	0.728	43%	0.432	S	S	*	.	H	α-helix	trans	-57.9	-44.7	175.9	-75.6	176.8	177.9	-175	-1.3	111.3	R354 S355 N361 A362	R354-R358 WeakPolarHBondContact O-CG 3.18Å; R354-R358 PolarHBondContact O-N 2.72Å; S355-R358 PolarHBondContact O-N 3.11Å; R358-N361 PolarHBondContact O-N 3.4Å; R358-A362 PolarHBondContact O-N 3.49Å
359	R	84.4	Confident	85.1	Confident	104 Å²	104	83.4 Å²	83.4	39%	0.392	40%	0.399	S	S	.	.	H	α-helix	trans	-62.6	-44.5	176.6	-173	177.6	74.2	-160.5	8.5	112.2	S355 K356 Q357 A362 Q363	S355-R359 WeakPolarHBondContact O-CB 3.22Å; S355-R359 PolarHBondContact O-N 3.49Å; K356-R359 PolarHBondContact O-N 3.16Å; Q357-R359 VanDerWaalsContact C-N 3.32Å; Q357-R359 PolarHBondContact O-N 2.85Å; R359-A362 PolarHBondContact O-N 3.01Å; R359-Q363 WeakPolarHBondContact O-CG 3.48Å; R359-Q363 PolarHBondContact O-N 3.16Å
360	Q	84.9	Confident	86.4	Confident	56 Å²	56	80.3 Å²	80.3	26%	0.262	38%	0.379	S	S	.	.	H	α-helix	trans	-62.8	-43.2	177.2	-75.2	174.7	-15.4	0	0	111.6	K356 Q357 A362 Q363 R364	K356-Q360 WeakPolarHBondContact O-CB 3.4Å; K356-Q360 VanDerWaalsContact O-CG 3.31Å; K356-Q360 WeakPolarHBondContact O-CG 3.09Å; K356-Q360 PolarHBondContact O-N 3.5Å; Q357-Q360 PolarHBondContact O-N 2.96Å; Q360-A362 VanDerWaalsContact C-N 3.34Å; Q360-A362 PolarHBondContact O-N 3.07Å; Q360-Q363 PolarHBondContact O-N 3.32Å; Q360-R364 WeakPolarHBondContact O-CB 3.27Å; Q360-R364 PolarHBondContact O-N 2.75Å
361	N	87.1	Confident	87	Confident	62 Å²	62	76.9 Å²	76.9	33%	0.332	36%	0.361	S	S	.	.	H	α-helix	trans	-61	-41.6	175.5	-72.2	-12.6	0	0	0	112.1	Q357 R358 R364 K365	Q357-N361 PolarHBondContact NE2-OD1 3.45Å; Q357-N361 WeakPolarHBondContact O-CB 3.32Å; Q357-N361 VanDerWaalsContact O-CG 3.27Å; Q357-N361 PolarHBondContact O-N 3.25Å; R358-N361 PolarHBondContact O-N 3.4Å; N361-R364 PolarHBondContact O-N 3.33Å; N361-K365 WeakPolarHBondContact O-CG 3.4Å; N361-K365 PolarHBondContact O-N 2.87Å; N361-K365 VanDerWaalsContact O-N 3.09Å
362	A	86.4	Confident	87.5	Confident	58 Å²	58	72.8 Å²	72.8	48%	0.479	34%	0.343	S	S	.	.	H	α-helix	trans	-64.9	-46.3	175.9	0	0	0	0	0	112	R358 R359 Q360 R364 K365 L366	R358-A362 PolarHBondContact O-N 3.49Å; R359-A362 PolarHBondContact O-N 3.01Å; Q360-A362 VanDerWaalsContact C-N 3.34Å; Q360-A362 PolarHBondContact O-N 3.07Å; A362-R364 VanDerWaalsContact C-N 3.32Å; A362-R364 PolarHBondContact O-N 2.86Å; A362-K365 PolarHBondContact O-N 2.88Å; A362-L366 PolarHBondContact O-N 3.16Å; A362-L366 VanDerWaalsContact O-N 3.09Å
363	Q	86.6	Confident	88	Confident	61 Å²	61	66.3 Å²	66.3	29%	0.285	31%	0.313	S	S	.	.	H	α-helix	trans	-61	-41.1	175.7	-72.4	-63.1	-37.4	0	0	111.9	R359 Q360 L366 T367	R359-Q363 WeakPolarHBondContact O-CG 3.48Å; R359-Q363 PolarHBondContact O-N 3.16Å; Q360-Q363 PolarHBondContact O-N 3.32Å; Q363-L366 PolarHBondContact O-N 3.05Å; Q363-T367 PolarHBondContact O-N 3.29Å; Q363-T367 PolarHBondContact O-OG1 3.41Å; Q363-T367 VanDerWaalsContact O-OG1 3.06Å
364	R	86.9	Confident	88.4	Confident	76 Å²	76	61.4 Å²	61.4	29%	0.287	29%	0.287	S	S	.	.	H	α-helix	trans	-60	-47.9	176.6	177.9	-177.3	169	-175.7	2.5	112	N240 Q360 N361 A362 L366 T367 I368	N240-R364 VanDerWaalsContact CG-CZ 3.42Å; N240-R364 PolarHBondContact ND2-NH2 2.99Å; N240-R364 VanDerWaalsContact ND2-NH2 3.18Å; N240-R364 PolarHBondContact OD1-NE 2.69Å; N240-R364 PolarHBondContact OD1-NH1 2.62Å; N240-R364 PolarHBondContact OD1-NH2 3.32Å; Q360-R364 WeakPolarHBondContact O-CB 3.27Å; Q360-R364 PolarHBondContact O-N 2.75Å; N361-R364 PolarHBondContact O-N 3.33Å; A362-R364 VanDerWaalsContact C-N 3.32Å; A362-R364 PolarHBondContact O-N 2.86Å; R364-L366 VanDerWaalsContact C-N 3.31Å; R364-L366 PolarHBondContact O-N 3.27Å; R364-T367 PolarHBondContact O-N 3.16Å; R364-I368 HydrophobicContact CG-CD1 4.04Å; R364-I368 WeakPolarHBondContact O-CG1 3.47Å; R364-I368 PolarHBondContact O-N 3.23Å
365	K	90.7	Very high	88.7	Confident	143 Å²	143	57.7 Å²	57.7	62%	0.622	28%	0.279	S	S	*	.	H	α-helix	trans	-59.3	-44.1	177.4	-72.3	177	-179.2	-177.6	0	111.3	N361 A362 I368 L369	N361-K365 WeakPolarHBondContact O-CG 3.4Å; N361-K365 PolarHBondContact O-N 2.87Å; N361-K365 VanDerWaalsContact O-N 3.09Å; A362-K365 PolarHBondContact O-N 2.88Å; K365-I368 PolarHBondContact O-N 3Å; K365-L369 PolarHBondContact O-N 3.46Å; K365-L369 VanDerWaalsContact O-N 3.14Å
366	L	89.1	Confident	89.2	Confident	14 Å²	14	55.9 Å²	55.9	7%	0.073	26%	0.263	C	S	.	.	H	α-helix	trans	-63.6	-40.7	176.8	-179.1	55.9	0	0	0	112.3	A69 Y70 R139 A362 Q363 R364 L369 L370	A69-L366 HydrophobicContact CB-CD2 4.35Å; Y70-L366 HydrophobicContact CE1-CD1 3.81Å; Y70-L366 HydrophobicContact CE2-CD2 4.44Å; R139-L366 VanDerWaalsContact NH1-CD2 3.26Å; A362-L366 PolarHBondContact O-N 3.16Å; A362-L366 VanDerWaalsContact O-N 3.09Å; Q363-L366 PolarHBondContact O-N 3.05Å; R364-L366 VanDerWaalsContact C-N 3.31Å; R364-L366 PolarHBondContact O-N 3.27Å; L366-L369 HydrophobicContact CD1-CD2 4.29Å; L366-L369 WeakPolarHBondContact O-CB 3.49Å; L366-L369 PolarHBondContact O-N 2.9Å; L366-L370 HydrophobicContact CD1-CD1 3.98Å; L366-L370 HydrophobicContact CD1-CG 4.47Å; L366-L370 HydrophobicContact CG-CD1 4.1Å; L366-L370 PolarHBondContact O-N 2.83Å
367	T	91	Very high	89.5	Confident	0 Å²	0	51.5 Å²	51.5	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-65.3	-43.5	175.7	-58.2	0	0	0	0	112.1	M143 L232 V236 Q363 R364 L369 L370 I371	M143-T367 HydrophobicContact CE-CG2 4.23Å; M143-T367 HydrophobicContact SD-CG2 3.3Å; M143-T367 WeakPolarHBondContact SD-CG2 3.5Å; M143-T367 PolarHBondContact SD-OG1 3.19Å; L232-T367 HydrophobicContact CD2-CG2 4.5Å; V236-T367 HydrophobicContact CG2-CG2 3.61Å; Q363-T367 PolarHBondContact O-N 3.29Å; Q363-T367 PolarHBondContact O-OG1 3.41Å; Q363-T367 VanDerWaalsContact O-OG1 3.06Å; R364-T367 PolarHBondContact O-N 3.16Å; T367-L369 VanDerWaalsContact C-N 3.29Å; T367-L369 PolarHBondContact O-N 3.48Å; T367-L370 PolarHBondContact O-N 3.34Å; T367-L370 VanDerWaalsContact O-N 3.08Å; T367-I371 HydrophobicContact CG2-CD1 3.87Å; T367-I371 HydrophobicContact CG2-CG1 4.17Å; T367-I371 WeakPolarHBondContact O-CG1 3.18Å; T367-I371 PolarHBondContact O-N 3.37Å
368	I	91	Very high	89.8	Confident	70 Å²	70	49 Å²	49	36%	0.359	23%	0.233	S	C	.	.	H	α-helix	trans	-58.6	-44.9	178.4	-68.9	166	0	0	0	110.4	V236 R364 K365 L370 I371 A372	V236-I368 HydrophobicContact CG1-CG1 4.37Å; R364-I368 HydrophobicContact CG-CD1 4.04Å; R364-I368 WeakPolarHBondContact O-CG1 3.47Å; R364-I368 PolarHBondContact O-N 3.23Å; K365-I368 PolarHBondContact O-N 3Å; I368-L370 VanDerWaalsContact C-N 3.33Å; I368-L370 PolarHBondContact O-N 3.19Å; I368-I371 PolarHBondContact O-N 2.63Å; I368-A372 PolarHBondContact O-N 2.74Å; I368-A372 VanDerWaalsContact O-N 3.07Å
369	L	92.3	Very high	90.2	Very high	2 Å²	2	44.8 Å²	44.8	1%	0.01	22%	0.224	C	C	.	.	H	α-helix	trans	-55.6	-48.5	173.3	168.5	67.6	0	0	0	111.5	M73 K365 L366 T367 A372 V373 L430 Y431 L434 N435	M73-L369 HydrophobicContact CE-CD2 4.13Å; K365-L369 PolarHBondContact O-N 3.46Å; K365-L369 VanDerWaalsContact O-N 3.14Å; L366-L369 HydrophobicContact CD1-CD2 4.29Å; L366-L369 WeakPolarHBondContact O-CB 3.49Å; L366-L369 PolarHBondContact O-N 2.9Å; T367-L369 VanDerWaalsContact C-N 3.29Å; T367-L369 PolarHBondContact O-N 3.48Å; L369-A372 WeakPolarHBondContact O-CB 3.4Å; L369-A372 PolarHBondContact O-N 3.29Å; L369-V373 HydrophobicContact CD1-CG2 4.18Å; L369-V373 HydrophobicContact CG-CG2 4.47Å; L369-V373 VanDerWaalsContact O-CG2 3.25Å; L369-V373 WeakPolarHBondContact O-CG2 3.34Å; L369-V373 PolarHBondContact O-N 3.18Å; L369-L430 HydrophobicContact CD1-CB 4.18Å; L369-L430 WeakPolarHBondContact CD1-O 3.14Å; L369-Y431 HydrophobicContact CD1-CD1 3.68Å; L369-Y431 HydrophobicContact CD1-CE1 4.13Å; L369-Y431 HydrophobicContact CD2-CD1 4.09Å; L369-Y431 HydrophobicContact CG-CD1 4.27Å; L369-Y431 HydrophobicContact CG-CE1 4.49Å; L369-L434 HydrophobicContact CB-CB 4.21Å; L369-L434 HydrophobicContact CD1-CB 3.8Å; L369-L434 HydrophobicContact CD1-CD1 4.18Å; L369-N435 HydrophobicContact CD2-CB 3.9Å
370	L	90.4	Very high	90.6	Very high	1 Å²	1	39.9 Å²	39.9	1%	0.005	21%	0.206	C	C	.	.	H	α-helix	trans	-70.2	-36.3	-176	-76.2	166.2	0	0	0	112.8	A69 M73 L135 R139 L366 T367 I368 A372 V373 I374	A69-L370 HydrophobicContact CB-CD1 4.1Å; M73-L370 HydrophobicContact CE-CD2 4.41Å; M73-L370 HydrophobicContact CG-CD2 4.13Å; M73-L370 HydrophobicContact SD-CD2 3.88Å; L135-L370 HydrophobicContact CD1-CD2 4.15Å; L135-L370 HydrophobicContact CD2-CD1 4.44Å; L135-L370 HydrophobicContact CD2-CD2 3.97Å; L135-L370 HydrophobicContact CG-CD2 4.48Å; R139-L370 HydrophobicContact CG-CB 4.07Å; R139-L370 HydrophobicContact CG-CD1 3.45Å; R139-L370 VanDerWaalsContact CG-CD1 3.45Å; R139-L370 HydrophobicContact CG-CG 4.36Å; L366-L370 HydrophobicContact CD1-CD1 3.98Å; L366-L370 HydrophobicContact CD1-CG 4.47Å; L366-L370 HydrophobicContact CG-CD1 4.1Å; L366-L370 PolarHBondContact O-N 2.83Å; T367-L370 PolarHBondContact O-N 3.34Å; T367-L370 VanDerWaalsContact O-N 3.08Å; I368-L370 VanDerWaalsContact C-N 3.33Å; I368-L370 PolarHBondContact O-N 3.19Å; L370-A372 VanDerWaalsContact C-N 3.31Å; L370-A372 PolarHBondContact O-N 3.19Å; L370-V373 PolarHBondContact O-N 3.37Å; L370-I374 WeakPolarHBondContact O-CD1 3.26Å; L370-I374 WeakPolarHBondContact O-CG1 3.27Å; L370-I374 PolarHBondContact O-N 3.3Å
371	I	91.7	Very high	91	Very high	16 Å²	16	38.1 Å²	38.1	8%	0.082	20%	0.198	C	C	.	.	H	α-helix	trans	-57.9	-46.9	169.9	-68.4	169.4	0	0	0	109.9	L232 V236 T367 I368 V373 I374 L375	L232-I371 HydrophobicContact CB-CD1 4.02Å; L232-I371 HydrophobicContact CB-CG1 4.02Å; V236-I371 HydrophobicContact CG2-CD1 3.87Å; T367-I371 HydrophobicContact CG2-CD1 3.87Å; T367-I371 HydrophobicContact CG2-CG1 4.17Å; T367-I371 WeakPolarHBondContact O-CG1 3.18Å; T367-I371 PolarHBondContact O-N 3.37Å; I368-I371 PolarHBondContact O-N 2.63Å; I371-V373 VanDerWaalsContact C-N 3.33Å; I371-V373 PolarHBondContact O-N 2.7Å; I371-I374 PolarHBondContact O-N 2.99Å; I371-L375 HydrophobicContact CG2-CD1 3.89Å; I371-L375 HydrophobicContact CG2-CG 4.25Å; I371-L375 WeakPolarHBondContact O-CB 3.32Å; I371-L375 VanDerWaalsContact O-CG 3.31Å; I371-L375 WeakPolarHBondContact O-CG 3.45Å; I371-L375 PolarHBondContact O-N 2.85Å
372	A	93.5	Very high	91.2	Very high	27 Å²	27	37.7 Å²	37.7	22%	0.223	20%	0.197	C	C	.	.	H	α-helix	trans	-61	-41.6	178.5	0	0	0	0	0	112.3	I368 L369 L370 L375 L376 L430 L434	I368-A372 PolarHBondContact O-N 2.74Å; I368-A372 VanDerWaalsContact O-N 3.07Å; L369-A372 WeakPolarHBondContact O-CB 3.4Å; L369-A372 PolarHBondContact O-N 3.29Å; L370-A372 VanDerWaalsContact C-N 3.31Å; L370-A372 PolarHBondContact O-N 3.19Å; A372-L375 PolarHBondContact O-N 3.27Å; A372-L376 WeakPolarHBondContact O-CB 3.4Å; A372-L376 PolarHBondContact O-N 2.91Å; A372-L430 HydrophobicContact CB-CD1 4.19Å; A372-L430 HydrophobicContact CB-CD2 4.1Å; A372-L434 HydrophobicContact CB-CD1 3.94Å
373	V	92.1	Very high	91.6	Very high	3 Å²	3	36.5 Å²	36.5	2%	0.018	18%	0.184	C	C	.	.	H	α-helix	trans	-63	-45.1	176.6	172.1	0	0	0	0	111.3	L76 L369 L370 I371 L376 F377 L430 Y431	L76-V373 HydrophobicContact CD2-CG1 4.47Å; L369-V373 HydrophobicContact CD1-CG2 4.18Å; L369-V373 HydrophobicContact CG-CG2 4.47Å; L369-V373 VanDerWaalsContact O-CG2 3.25Å; L369-V373 WeakPolarHBondContact O-CG2 3.34Å; L369-V373 PolarHBondContact O-N 3.18Å; L370-V373 PolarHBondContact O-N 3.37Å; I371-V373 VanDerWaalsContact C-N 3.33Å; I371-V373 PolarHBondContact O-N 2.7Å; V373-L376 PolarHBondContact O-N 2.93Å; V373-F377 PolarHBondContact O-N 3.34Å; V373-L430 HydrophobicContact CB-CD1 4.42Å; V373-L430 HydrophobicContact CG2-CB 4.39Å; V373-L430 HydrophobicContact CG2-CD1 3.91Å; V373-Y431 HydrophobicContact CG2-CD1 4.41Å; V373-Y431 HydrophobicContact CG2-CE1 3.51Å
374	I	91.1	Very high	91.9	Very high	0 Å²	0	34 Å²	34	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-69.4	-38.9	-179.4	-54.9	156.8	0	0	0	110.6	T132 A136 L225 N229 L232 L370 I371 L376 F377 L378	T132-I374 HydrophobicContact CG2-CB 4.2Å; T132-I374 HydrophobicContact CG2-CG1 3.8Å; T132-I374 HydrophobicContact CG2-CG2 3.78Å; A136-I374 HydrophobicContact CB-CD1 3.96Å; L225-I374 HydrophobicContact CB-CG2 4.12Å; L225-I374 HydrophobicContact CD1-CG2 4.17Å; L225-I374 HydrophobicContact CD2-CG2 3.72Å; L225-I374 HydrophobicContact CG-CG2 4.2Å; N229-I374 WeakPolarHBondContact ND2-CG2 3.45Å; N229-I374 WeakPolarHBondContact OD1-CB 3.46Å; N229-I374 WeakPolarHBondContact OD1-CD1 3.27Å; N229-I374 WeakPolarHBondContact OD1-CG2 3.4Å; L232-I374 HydrophobicContact CD1-CD1 4.32Å; L370-I374 WeakPolarHBondContact O-CD1 3.26Å; L370-I374 WeakPolarHBondContact O-CG1 3.27Å; L370-I374 PolarHBondContact O-N 3.3Å; I371-I374 PolarHBondContact O-N 2.99Å; I374-L376 VanDerWaalsContact C-N 3.34Å; I374-L376 PolarHBondContact O-N 2.76Å; I374-F377 WeakPolarHBondContact O-CB 3.47Å; I374-F377 PolarHBondContact O-N 3.4Å; I374-L378 WeakPolarHBondContact O-CG 3.45Å; I374-L378 PolarHBondContact O-N 3.45Å
375	L	92.4	Very high	92.1	Very high	80 Å²	80	30.7 Å²	30.7	42%	0.419	16%	0.161	S	C	.	.	H	α-helix	trans	-62.4	-42.3	174.6	-71.8	176.7	0	0	0	111.7	I371 A372 F377 L378 I379	I371-L375 HydrophobicContact CG2-CD1 3.89Å; I371-L375 HydrophobicContact CG2-CG 4.25Å; I371-L375 WeakPolarHBondContact O-CB 3.32Å; I371-L375 VanDerWaalsContact O-CG 3.31Å; I371-L375 WeakPolarHBondContact O-CG 3.45Å; I371-L375 PolarHBondContact O-N 2.85Å; A372-L375 PolarHBondContact O-N 3.27Å; L375-F377 VanDerWaalsContact C-N 3.33Å; L375-F377 PolarHBondContact O-N 3.42Å; L375-L378 PolarHBondContact O-N 3.07Å; L375-I379 VanDerWaalsContact O-CG1 3.3Å; L375-I379 WeakPolarHBondContact O-CG1 3.44Å; L375-I379 PolarHBondContact O-N 3.21Å
376	L	94.2	Very high	92.1	Very high	32 Å²	32	27 Å²	27	17%	0.168	15%	0.148	C	C	.	.	H	α-helix	trans	-60.9	-43.3	174.7	-178.1	62.8	0	0	0	111.4	A372 V373 I374 I379 G380 A423 T427 L430	A372-L376 WeakPolarHBondContact O-CB 3.4Å; A372-L376 PolarHBondContact O-N 2.91Å; V373-L376 PolarHBondContact O-N 2.93Å; I374-L376 VanDerWaalsContact C-N 3.34Å; I374-L376 PolarHBondContact O-N 2.76Å; L376-I379 PolarHBondContact O-N 3.14Å; L376-G380 PolarHBondContact O-N 2.95Å; L376-A423 HydrophobicContact CD1-CB 4.07Å; L376-A423 WeakPolarHBondContact CD2-O 3.4Å; L376-A423 HydrophobicContact CG-CB 4.11Å; L376-A423 WeakPolarHBondContact O-CB 3.22Å; L376-T427 HydrophobicContact CD2-CG2 4.35Å; L376-L430 HydrophobicContact CB-CD1 4.08Å; L376-L430 HydrophobicContact CD2-CD1 3.54Å; L376-L430 HydrophobicContact CD2-CG 4.21Å; L376-L430 HydrophobicContact CG-CD1 4.47Å
377	F	91.6	Very high	92.3	Very high	15 Å²	15	26.6 Å²	26.6	7%	0.066	15%	0.147	C	C	.	.	H	α-helix	trans	-58.3	-47.2	173.5	178.7	-87.1	0	0	0	111.7	A129 T132 L222 L225 V373 I374 L375 I379 G380 Q381 F424	A129-F377 HydrophobicContact CB-CZ 3.79Å; T132-F377 HydrophobicContact CG2-CB 4.45Å; T132-F377 HydrophobicContact CG2-CD1 4.28Å; T132-F377 HydrophobicContact CG2-CG 4.23Å; L222-F377 HydrophobicContact CD2-CE1 4.28Å; L225-F377 HydrophobicContact CD1-CD1 3.72Å; L225-F377 HydrophobicContact CD1-CE1 3.68Å; V373-F377 PolarHBondContact O-N 3.34Å; I374-F377 WeakPolarHBondContact O-CB 3.47Å; I374-F377 PolarHBondContact O-N 3.4Å; L375-F377 VanDerWaalsContact C-N 3.33Å; L375-F377 PolarHBondContact O-N 3.42Å; F377-I379 PolarHBondContact O-N 2.89Å; F377-G380 PolarHBondContact O-N 3.49Å; F377-Q381 HydrophobicContact CD1-CB 4.29Å; F377-Q381 HydrophobicContact CD1-CG 4.12Å; F377-Q381 HydrophobicContact CD2-CG 4Å; F377-Q381 HydrophobicContact CE1-CB 3.96Å; F377-Q381 HydrophobicContact CE1-CG 3.79Å; F377-Q381 HydrophobicContact CE2-CG 3.68Å; F377-Q381 HydrophobicContact CG-CG 4.21Å; F377-Q381 HydrophobicContact CZ-CB 4.18Å; F377-Q381 HydrophobicContact CZ-CG 3.55Å; F377-Q381 VanDerWaalsContact O-CB 3.25Å; F377-Q381 WeakPolarHBondContact O-CB 3.26Å; F377-Q381 WeakPolarHBondContact O-CG 3.39Å; F377-Q381 PolarHBondContact O-N 3Å; F377-F424 HydrophobicContact CD2-CE1 4.26Å; F377-F424 HydrophobicContact CE2-CE1 4.24Å
378	L	92.1	Very high	92.2	Very high	17 Å²	17	29 Å²	29	9%	0.089	16%	0.156	C	C	.	.	H	α-helix	trans	-62.1	-42.9	179.3	-74.5	177.5	0	0	0	112.7	L222 L225 N229 I374 L375 G380 Q381 V382	L222-L378 HydrophobicContact CD2-CD2 3.71Å; L225-L378 HydrophobicContact CB-CD1 4.38Å; L225-L378 HydrophobicContact CB-CD2 3.84Å; L225-L378 HydrophobicContact CB-CG 4.34Å; L225-L378 HydrophobicContact CD1-CD2 4.36Å; N229-L378 VanDerWaalsContact ND2-CD1 3.27Å; N229-L378 WeakPolarHBondContact ND2-CD1 3.39Å; I374-L378 WeakPolarHBondContact O-CG 3.45Å; I374-L378 PolarHBondContact O-N 3.45Å; L375-L378 PolarHBondContact O-N 3.07Å; L378-G380 VanDerWaalsContact C-N 3.26Å; L378-G380 PolarHBondContact O-N 3.34Å; L378-Q381 PolarHBondContact O-N 3.33Å; L378-V382 HydrophobicContact CB-CG2 4.45Å; L378-V382 HydrophobicContact CD2-CG2 4.05Å; L378-V382 WeakPolarHBondContact O-CB 3.46Å; L378-V382 VanDerWaalsContact O-CG2 3.28Å; L378-V382 WeakPolarHBondContact O-CG2 3.3Å; L378-V382 PolarHBondContact O-N 2.92Å
379	I	93.9	Very high	92	Very high	104 Å²	104	28.5 Å²	28.5	53%	0.533	16%	0.156	S	C	.	.	H	α-helix	trans	-60	-39.2	178.2	-70.6	165.6	0	0	0	111	L375 L376 F377 P383 L419	L375-I379 VanDerWaalsContact O-CG1 3.3Å; L375-I379 WeakPolarHBondContact O-CG1 3.44Å; L375-I379 PolarHBondContact O-N 3.21Å; L376-I379 PolarHBondContact O-N 3.14Å; F377-I379 PolarHBondContact O-N 2.89Å; I379-P383 WeakPolarHBondContact O-CD 3.42Å; I379-P383 WeakPolarHBondContact O-CG 3.46Å; I379-L419 HydrophobicContact CG2-CD1 4.45Å; I379-L419 WeakPolarHBondContact O-CD2 3.23Å
380	G	94.1	Very high	91.7	Very high	1 Å²	1	31.9 Å²	31.9	1%	0.01	17%	0.169	C	C	.	.	H	α-helix	trans	-74.1	-49.8	176.5	0	0	0	0	0	113.5	L376 F377 L378	L376-G380 PolarHBondContact O-N 2.95Å; F377-G380 PolarHBondContact O-N 3.49Å; L378-G380 VanDerWaalsContact C-N 3.26Å; L378-G380 PolarHBondContact O-N 3.34Å
381	Q	92.4	Very high	91.6	Very high	19 Å²	19	32.8 Å²	32.8	9%	0.089	17%	0.174	C	C	.	.	H	α-helix	trans	-84.2	-32.9	-165.2	-73.3	-88	25.8	0	0	114.3	L222 F377 L378 Q384 S385 F424	L222-Q381 HydrophobicContact CD2-CB 4.13Å; F377-Q381 HydrophobicContact CD1-CB 4.29Å; F377-Q381 HydrophobicContact CD1-CG 4.12Å; F377-Q381 HydrophobicContact CD2-CG 4Å; F377-Q381 HydrophobicContact CE1-CB 3.96Å; F377-Q381 HydrophobicContact CE1-CG 3.79Å; F377-Q381 HydrophobicContact CE2-CG 3.68Å; F377-Q381 HydrophobicContact CG-CG 4.21Å; F377-Q381 HydrophobicContact CZ-CB 4.18Å; F377-Q381 HydrophobicContact CZ-CG 3.55Å; F377-Q381 VanDerWaalsContact O-CB 3.25Å; F377-Q381 WeakPolarHBondContact O-CB 3.26Å; F377-Q381 WeakPolarHBondContact O-CG 3.39Å; F377-Q381 PolarHBondContact O-N 3Å; L378-Q381 PolarHBondContact O-N 3.33Å; Q381-Q384 PolarHBondContact O-N 2.83Å; Q381-S385 WeakPolarHBondContact O-CB 3.19Å; Q381-S385 PolarHBondContact O-N 3.42Å; Q381-F424 VanDerWaalsContact NE2-CZ 3.29Å
382	V	92	Very high	91.5	Very high	53 Å²	53	32.4 Å²	32.4	32%	0.321	17%	0.172	S	C	.	.	H	α-helix	trans	-61.1	-51.8	-179.8	174	0	0	0	0	110.6	L222 L378 Q384 S385	L222-V382 HydrophobicContact CD1-CG2 4.15Å; L222-V382 HydrophobicContact CD2-CG2 3.73Å; L222-V382 HydrophobicContact CG-CG2 4.35Å; L378-V382 HydrophobicContact CB-CG2 4.45Å; L378-V382 HydrophobicContact CD2-CG2 4.05Å; L378-V382 WeakPolarHBondContact O-CB 3.46Å; L378-V382 VanDerWaalsContact O-CG2 3.28Å; L378-V382 WeakPolarHBondContact O-CG2 3.3Å; L378-V382 PolarHBondContact O-N 2.92Å; V382-Q384 PolarHBondContact O-N 3.13Å; V382-S385 PolarHBondContact O-N 2.83Å; V382-S385 PolarHBondContact O-OG 3.5Å
383	P	94.2	Very high	91.3	Very high	33 Å²	33	32 Å²	32	21%	0.214	17%	0.167	C	C	.	.	H	α-helix	trans	-63	-40	176.8	-23	36.5	0	0	0	112.9	I379 S385 L386 A387 Y412 T416 L419	I379-P383 WeakPolarHBondContact O-CD 3.42Å; I379-P383 WeakPolarHBondContact O-CG 3.46Å; P383-S385 VanDerWaalsContact C-N 3.31Å; P383-S385 PolarHBondContact O-N 3.18Å; P383-L386 PolarHBondContact O-N 2.93Å; P383-A387 PolarHBondContact O-N 3.38Å; P383-Y412 PolarHBondContact O-OH 2.64Å; P383-Y412 VanDerWaalsContact O-OH 3.12Å; P383-T416 HydrophobicContact CB-CG2 3.48Å; P383-T416 VanDerWaalsContact CB-CG2 3.48Å; P383-L419 HydrophobicContact CB-CD2 4.47Å; P383-L419 HydrophobicContact CG-CD2 4.08Å
384	Q	93.7	Very high	91.2	Very high	8 Å²	8	35.7 Å²	35.7	4%	0.037	19%	0.189	C	C	.	.	H	α-helix	trans	-62	-37.7	177.6	-172	-170.2	-3	0	0	112.1	E125 Q381 V382 L386 A387 I417 A420	E125-Q384 PolarHBondContact OE1-NE2 3.12Å; Q381-Q384 PolarHBondContact O-N 2.83Å; V382-Q384 PolarHBondContact O-N 3.13Å; Q384-L386 VanDerWaalsContact C-N 3.26Å; Q384-L386 PolarHBondContact O-N 3.48Å; Q384-A387 WeakPolarHBondContact O-CB 3.38Å; Q384-A387 PolarHBondContact O-N 3.4Å; Q384-I417 HydrophobicContact CG-CG1 4.4Å; Q384-A420 HydrophobicContact CB-CB 4.19Å; Q384-A420 HydrophobicContact CG-CB 4.39Å
385	S	90.9	Very high	91.1	Very high	7 Å²	7	40.5 Å²	40.5	5%	0.049	21%	0.214	C	C	.	.	H	α-helix	trans	-61.3	-34.4	179.1	73.5	0	0	0	0	112.7	Q381 V382 P383 A387 Y388	Q381-S385 WeakPolarHBondContact O-CB 3.19Å; Q381-S385 PolarHBondContact O-N 3.42Å; V382-S385 PolarHBondContact O-N 2.83Å; V382-S385 PolarHBondContact O-OG 3.5Å; P383-S385 VanDerWaalsContact C-N 3.31Å; P383-S385 PolarHBondContact O-N 3.18Å; S385-A387 VanDerWaalsContact C-N 3.27Å; S385-A387 PolarHBondContact O-N 3.1Å; S385-Y388 WeakPolarHBondContact O-CD2 3.33Å; S385-Y388 PolarHBondContact O-N 3.43Å
386	L	91.4	Very high	90.9	Very high	65 Å²	65	39.8 Å²	39.8	34%	0.34	23%	0.227	S	C	.	.	H	α-helix	trans	-73.4	-19.1	176	-61.5	177	0	0	0	112.7	P383 Q384 Y388 V391 Y412	P383-L386 PolarHBondContact O-N 2.93Å; Q384-L386 VanDerWaalsContact C-N 3.26Å; Q384-L386 PolarHBondContact O-N 3.48Å; L386-Y388 VanDerWaalsContact C-N 3.27Å; L386-Y388 PolarHBondContact O-N 3.2Å; L386-V391 HydrophobicContact CD2-CG1 3.97Å; L386-Y412 HydrophobicContact CB-CE1 4.16Å; L386-Y412 WeakPolarHBondContact CB-OH 3.26Å
387	A	91.8	Very high	90.7	Very high	6 Å²	6	42 Å²	42	5%	0.05	24%	0.241	C	C	.	.	T	Hydrogen-bonded Turn	trans	-80.3	-5.3	178.1	0	0	0	0	0	113.4	P383 Q384 S385 V389 Y409 Y412 R413 T416	P383-A387 PolarHBondContact O-N 3.38Å; Q384-A387 WeakPolarHBondContact O-CB 3.38Å; Q384-A387 PolarHBondContact O-N 3.4Å; S385-A387 VanDerWaalsContact C-N 3.27Å; S385-A387 PolarHBondContact O-N 3.1Å; A387-V389 PolarHBondContact O-N 3.37Å; A387-Y409 VanDerWaalsContact O-CE2 3.31Å; A387-Y409 WeakPolarHBondContact O-CE2 3.48Å; A387-Y412 HydrophobicContact CB-CD1 3.73Å; A387-Y412 HydrophobicContact CB-CE1 3.71Å; A387-R413 HydrophobicContact CB-CB 4.34Å; A387-R413 HydrophobicContact CB-CG 4.39Å; A387-T416 WeakPolarHBondContact CB-OG1 3.41Å
388	Y	88.9	Confident	90.5	Very high	51 Å²	51	42.3 Å²	42.3	20%	0.2	25%	0.245	C	C	.	.	S	Bend	trans	-64.1	131.6	173.5	-83	-100.9	0	0	0	110.1	N122 Q218 S385 L386 R390 V391 F392	N122-Y388 PolarHBondContact OD1-OH 3.49Å; Q218-Y388 VanDerWaalsContact NE2-CE1 3.31Å; S385-Y388 WeakPolarHBondContact O-CD2 3.33Å; S385-Y388 PolarHBondContact O-N 3.43Å; L386-Y388 VanDerWaalsContact C-N 3.27Å; L386-Y388 PolarHBondContact O-N 3.2Å; Y388-R390 VanDerWaalsContact C-N 3.31Å; Y388-R390 PolarHBondContact O-N 3.08Å; Y388-R390 VanDerWaalsContact O-N 3.12Å; Y388-V391 PolarHBondContact O-N 2.84Å; Y388-F392 PolarHBondContact O-N 3.36Å
389	V	87.3	Confident	90.3	Very high	59 Å²	59	43.8 Å²	43.8	36%	0.358	26%	0.257	S	S	.	.	H	α-helix	trans	-46.2	-51.3	-170	173.8	0	0	0	0	112.6	A387 F392 T393 I403 Y409	A387-V389 PolarHBondContact O-N 3.37Å; V389-F392 PolarHBondContact O-N 3.01Å; V389-T393 HydrophobicContact CG1-CG2 4.41Å; V389-T393 WeakPolarHBondContact O-CB 3.36Å; V389-T393 WeakPolarHBondContact O-CG2 3.3Å; V389-T393 PolarHBondContact O-N 3.37Å; V389-T393 PolarHBondContact O-OG1 3.28Å; V389-I403 HydrophobicContact CG1-CG1 4.33Å; V389-Y409 VanDerWaalsContact CG2-OH 3.22Å; V389-Y409 WeakPolarHBondContact CG2-OH 3.27Å
390	R	86.1	Confident	89.7	Confident	73 Å²	73	42.6 Å²	42.6	28%	0.275	25%	0.251	S	S	.	.	H	α-helix	trans	-62	-47.9	-178.7	-67.8	-65.6	-171.2	-147.8	1.2	112	I214 Y388 T393 T394	I214-R390 HydrophobicContact CD1-CB 4.01Å; Y388-R390 VanDerWaalsContact C-N 3.31Å; Y388-R390 PolarHBondContact O-N 3.08Å; Y388-R390 VanDerWaalsContact O-N 3.12Å; R390-T393 PolarHBondContact O-N 3.08Å; R390-T393 PolarHBondContact O-OG1 3.43Å; R390-T394 WeakPolarHBondContact O-CG2 3.15Å; R390-T394 PolarHBondContact O-N 3.46Å; R390-T394 PolarHBondContact O-OG1 3.32Å
391	V	88.6	Confident	89	Confident	19 Å²	19	49.8 Å²	49.8	12%	0.115	29%	0.289	C	S	.	.	H	α-helix	trans	-60.8	-50.6	178.9	-177.9	0	0	0	0	110.2	I214 L386 Y388 T393 T394 L395	I214-V391 HydrophobicContact CD1-CG2 3.64Å; I214-V391 HydrophobicContact CG1-CG2 3.95Å; I214-V391 HydrophobicContact CG2-CG2 3.8Å; L386-V391 HydrophobicContact CD2-CG1 3.97Å; Y388-V391 PolarHBondContact O-N 2.84Å; V391-T393 VanDerWaalsContact C-N 3.32Å; V391-T393 PolarHBondContact O-N 2.86Å; V391-T394 PolarHBondContact O-N 3.42Å; V391-T394 PolarHBondContact O-OG1 3.26Å; V391-L395 PolarHBondContact O-N 2.66Å
392	F	90.1	Very high	88.5	Confident	9 Å²	9	54.7 Å²	54.7	4%	0.039	31%	0.312	C	S	.	.	H	α-helix	trans	-59.4	-42.9	-179.6	-164.8	-89.1	0	0	0	112.3	Y388 V389 T394 L395 V397 C398 I403 T408 Y409 Y412	Y388-F392 PolarHBondContact O-N 3.36Å; V389-F392 PolarHBondContact O-N 3.01Å; F392-T394 VanDerWaalsContact C-N 3.28Å; F392-T394 PolarHBondContact O-N 3.44Å; F392-L395 WeakPolarHBondContact O-CB 3.43Å; F392-L395 PolarHBondContact O-N 2.86Å; F392-L395 VanDerWaalsContact O-N 3.17Å; F392-V397 HydrophobicContact CE1-CB 3.83Å; F392-V397 HydrophobicContact CE1-CG1 3.89Å; F392-V397 HydrophobicContact CZ-CB 4.03Å; F392-V397 HydrophobicContact CZ-CG1 3.84Å; F392-C398 HydrophobicContact CE1-CB 4.25Å; F392-I403 HydrophobicContact CD1-CD1 4.1Å; F392-T408 HydrophobicContact CZ-CG2 4.33Å; F392-Y409 HydrophobicContact CB-CD2 4.16Å; F392-Y409 HydrophobicContact CB-CE2 4.27Å; F392-Y409 AromaticContact CD1-CD2 3.61Å; F392-Y409 HydrophobicContact CD1-CD2 3.61Å; F392-Y409 HydrophobicContact CD1-CE2 4.5Å; F392-Y409 HydrophobicContact CD1-CG 4.3Å; F392-Y409 HydrophobicContact CD2-CD2 4.15Å; F392-Y409 AromaticContact CE1-CD2 3.99Å; F392-Y409 HydrophobicContact CE1-CD2 3.99Å; F392-Y409 HydrophobicContact CE1-CG 4.35Å; F392-Y409 HydrophobicContact CE2-CD2 4.48Å; F392-Y409 AromaticContact CG-CD2 3.7Å; F392-Y409 HydrophobicContact CG-CD2 3.7Å; F392-Y409 HydrophobicContact CG-CE2 4.28Å; F392-Y409 HydrophobicContact CZ-CD2 4.4Å; F392-Y412 HydrophobicContact CD2-CD1 4.04Å; F392-Y412 HydrophobicContact CD2-CE1 4.41Å; F392-Y412 AromaticContact CE2-CD1 3.84Å; F392-Y412 HydrophobicContact CE2-CD1 3.84Å; F392-Y412 HydrophobicContact CE2-CE1 4.46Å; F392-Y412 HydrophobicContact CE2-CG 4Å
393	T	89.5	Confident	88	Confident	19 Å²	19	53 Å²	53	12%	0.117	30%	0.301	C	S	.	.	H	α-helix	trans	-67.4	-29	178	57.5	0	0	0	0	112.8	V389 R390 V391 L395 G396 C398 I400 I403	V389-T393 HydrophobicContact CG1-CG2 4.41Å; V389-T393 WeakPolarHBondContact O-CB 3.36Å; V389-T393 WeakPolarHBondContact O-CG2 3.3Å; V389-T393 PolarHBondContact O-N 3.37Å; V389-T393 PolarHBondContact O-OG1 3.28Å; R390-T393 PolarHBondContact O-N 3.08Å; R390-T393 PolarHBondContact O-OG1 3.43Å; V391-T393 VanDerWaalsContact C-N 3.32Å; V391-T393 PolarHBondContact O-N 2.86Å; T393-L395 VanDerWaalsContact C-N 3.27Å; T393-L395 PolarHBondContact O-N 3.38Å; T393-G396 PolarHBondContact O-N 3.28Å; T393-C398 WeakPolarHBondContact CA-O 3.26Å; T393-I400 HydrophobicContact CG2-CB 4.37Å; T393-I400 HydrophobicContact CG2-CG1 3.59Å; T393-I403 HydrophobicContact CG2-CD1 3.93Å; T393-I403 HydrophobicContact CG2-CG1 4.42Å
394	T	88.6	Confident	87.2	Confident	79 Å²	79	56.8 Å²	56.8	49%	0.485	32%	0.316	S	S	.	.	H	α-helix	trans	-72.7	-19.2	175.2	62.5	0	0	0	0	113.5	W211 R390 V391 F392 G396	W211-T394 HydrophobicContact CH2-CG2 3.55Å; W211-T394 HydrophobicContact CZ2-CG2 3.71Å; R390-T394 WeakPolarHBondContact O-CG2 3.15Å; R390-T394 PolarHBondContact O-N 3.46Å; R390-T394 PolarHBondContact O-OG1 3.32Å; V391-T394 PolarHBondContact O-N 3.42Å; V391-T394 PolarHBondContact O-OG1 3.26Å; F392-T394 VanDerWaalsContact C-N 3.28Å; F392-T394 PolarHBondContact O-N 3.44Å; T394-G396 PolarHBondContact O-N 3Å
395	L	90	Very high	86.5	Confident	101 Å²	101	60.6 Å²	60.6	53%	0.529	34%	0.34	S	S	.	.	T	Hydrogen-bonded Turn	trans	-74.3	-6.6	172.6	-60.7	174.4	0	0	0	112.8	V391 F392 T393 V397	V391-L395 PolarHBondContact O-N 2.66Å; F392-L395 WeakPolarHBondContact O-CB 3.43Å; F392-L395 PolarHBondContact O-N 2.86Å; F392-L395 VanDerWaalsContact O-N 3.17Å; T393-L395 VanDerWaalsContact C-N 3.27Å; T393-L395 PolarHBondContact O-N 3.38Å; L395-V397 HydrophobicContact CB-CG2 4.28Å; L395-V397 PolarHBondContact O-N 3.12Å
396	G	88.5	Confident	86.2	Confident	66 Å²	66	60.8 Å²	60.8	68%	0.68	34%	0.341	S	S	*	.	T	Hydrogen-bonded Turn	trans	75.7	3.9	176.5	0	0	0	0	0	115.1	T393 T394	T393-G396 PolarHBondContact O-N 3.28Å; T394-G396 PolarHBondContact O-N 3Å
397	V	89.5	Confident	86.1	Confident	78 Å²	78	60.4 Å²	60.4	47%	0.473	34%	0.341	S	S	.	.	S	Bend	trans	-68.4	-41.2	178.8	-178.9	0	0	0	0	111.3	F392 L395 T408	F392-V397 HydrophobicContact CE1-CB 3.83Å; F392-V397 HydrophobicContact CE1-CG1 3.89Å; F392-V397 HydrophobicContact CZ-CB 4.03Å; F392-V397 HydrophobicContact CZ-CG1 3.84Å; L395-V397 HydrophobicContact CB-CG2 4.28Å; L395-V397 PolarHBondContact O-N 3.12Å; V397-T408 HydrophobicContact CG1-CG2 3.92Å
398	C	88	Confident	86	Confident	22 Å²	22	64.1 Å²	64.1	15%	0.149	36%	0.363	C	S	.	.	S	Bend	trans	-142.8	142.3	178.2	-75.2	0	0	0	0	110.7	F392 T393 I403 C406	F392-C398 HydrophobicContact CE1-CB 4.25Å; T393-C398 WeakPolarHBondContact CA-O 3.26Å; C398-I403 HydrophobicContact CB-CD1 4.07Å; C398-C406 HydrophobicContact CB-CB 3.73Å; C398-C406 WeakPolarHBondContact CB-SG 3.27Å; C398-C406 WeakPolarHBondContact SG-CB 3.21Å; C398-C406 CovalentContact SG-SG 2.02Å; C398-C406 PolarHBondContact SG-SG 3.2Å
399	S	86.5	Confident	86.1	Confident	47 Å²	47	62.1 Å²	62.1	33%	0.329	36%	0.355	S	S	.	.			trans	-72.9	155.5	174	65.4	0	0	0	0	111	D401 Q402 I403	S399-D401 PolarHBondContact O-N 3.15Å; S399-Q402 PolarHBondContact O-N 3.47Å; S399-Q402 VanDerWaalsContact OG-CB 3.32Å; S399-Q402 WeakPolarHBondContact OG-CB 3.34Å; S399-Q402 VanDerWaalsContact OG-CG 3.32Å; S399-Q402 WeakPolarHBondContact OG-CG 3.17Å; S399-Q402 PolarHBondContact OG-N 2.94Å; S399-Q402 PolarHBondContact OG-OE1 2.98Å; S399-I403 PolarHBondContact O-N 3.24Å; S399-I403 VanDerWaalsContact O-N 3.07Å
400	I	81.5	Confident	86.2	Confident	80 Å²	80	61 Å²	61	41%	0.41	35%	0.346	S	S	.	.	T	Hydrogen-bonded Turn	trans	-58.4	-38.1	175.6	-69.7	159.8	0	0	0	110.6	T393 Q402 I403	T393-I400 HydrophobicContact CG2-CB 4.37Å; T393-I400 HydrophobicContact CG2-CG1 3.59Å; I400-Q402 VanDerWaalsContact C-N 3.33Å; I400-Q402 PolarHBondContact O-N 3.12Å; I400-I403 WeakPolarHBondContact O-CG2 3.45Å; I400-I403 PolarHBondContact O-N 3.34Å
401	D	78.8	Confident	86.5	Confident	151 Å²	151	60.1 Å²	60.1	81%	0.807	35%	0.346	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.7	-27.7	-176.9	-56.8	-41.1	0	0	0	112.8	S399	S399-D401 PolarHBondContact O-N 3.15Å
402	Q	82.6	Confident	86.7	Confident	122 Å²	122	62.5 Å²	62.5	57%	0.57	35%	0.354	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101.9	4.6	179.5	-62.5	168.5	-30.9	0	0	113	S399 I400 Q404 T405 C406	S399-Q402 PolarHBondContact O-N 3.47Å; S399-Q402 VanDerWaalsContact OG-CB 3.32Å; S399-Q402 WeakPolarHBondContact OG-CB 3.34Å; S399-Q402 VanDerWaalsContact OG-CG 3.32Å; S399-Q402 WeakPolarHBondContact OG-CG 3.17Å; S399-Q402 PolarHBondContact OG-N 2.94Å; S399-Q402 PolarHBondContact OG-OE1 2.98Å; I400-Q402 VanDerWaalsContact C-N 3.33Å; I400-Q402 PolarHBondContact O-N 3.12Å; Q402-Q404 PolarHBondContact O-N 3.06Å; Q402-Q404 VanDerWaalsContact O-N 3.14Å; Q402-T405 PolarHBondContact O-N 3.26Å; Q402-T405 PolarHBondContact O-OG1 3.32Å; Q402-C406 WeakPolarHBondContact O-CB 3.12Å; Q402-C406 PolarHBondContact O-N 3.32Å
403	I	80.7	Confident	86.9	Confident	19 Å²	19	65.3 Å²	65.3	10%	0.097	36%	0.364	C	S	.	.	T	Hydrogen-bonded Turn	trans	-61.2	-29.9	-173.9	-160.1	64.5	0	0	0	112.4	V389 F392 T393 C398 S399 I400 T405 Y409	V389-I403 HydrophobicContact CG1-CG1 4.33Å; F392-I403 HydrophobicContact CD1-CD1 4.1Å; T393-I403 HydrophobicContact CG2-CD1 3.93Å; T393-I403 HydrophobicContact CG2-CG1 4.42Å; C398-I403 HydrophobicContact CB-CD1 4.07Å; S399-I403 PolarHBondContact O-N 3.24Å; S399-I403 VanDerWaalsContact O-N 3.07Å; I400-I403 WeakPolarHBondContact O-CG2 3.45Å; I400-I403 PolarHBondContact O-N 3.34Å; I403-T405 VanDerWaalsContact C-N 3.32Å; I403-T405 PolarHBondContact O-N 3.24Å; I403-Y409 HydrophobicContact CD1-CD1 3.79Å; I403-Y409 HydrophobicContact CD1-CD2 3.67Å; I403-Y409 HydrophobicContact CD1-CE1 4.29Å; I403-Y409 HydrophobicContact CD1-CE2 4.18Å; I403-Y409 HydrophobicContact CD1-CG 3.45Å; I403-Y409 VanDerWaalsContact CD1-CG 3.45Å; I403-Y409 HydrophobicContact CG1-CD1 3.72Å; I403-Y409 HydrophobicContact CG1-CD2 4.29Å; I403-Y409 HydrophobicContact CG1-CE1 3.88Å; I403-Y409 HydrophobicContact CG1-CE2 4.41Å; I403-Y409 HydrophobicContact CG1-CG 3.95Å
404	Q	77.5	Confident	87	Confident	112 Å²	112	65.4 Å²	65.4	52%	0.523	36%	0.364	S	S	.	.	T	Hydrogen-bonded Turn	trans	-68.6	-29	178.7	-69.3	-175.2	-23.5	0	0	112.8	Q402 H410	Q402-Q404 PolarHBondContact O-N 3.06Å; Q402-Q404 VanDerWaalsContact O-N 3.14Å; Q404-H410 PolarHBondContact O-NE2 2.69Å
405	T	79.5	Confident	87.3	Confident	88 Å²	88	66.4 Å²	66.4	54%	0.54	37%	0.365	S	S	.	.	T	Hydrogen-bonded Turn	trans	-104.8	-4.2	-179.5	56.2	0	0	0	0	113.2	Q402 I403 V407	Q402-T405 PolarHBondContact O-N 3.26Å; Q402-T405 PolarHBondContact O-OG1 3.32Å; I403-T405 VanDerWaalsContact C-N 3.32Å; I403-T405 PolarHBondContact O-N 3.24Å; T405-V407 PolarHBondContact O-N 3.02Å; T405-V407 VanDerWaalsContact O-N 3.11Å
406	C	85.6	Confident	87.6	Confident	10 Å²	10	61.8 Å²	61.8	7%	0.068	34%	0.341	C	S	.	.			trans	-71.2	102.6	-179.2	173.1	0	0	0	0	112.1	C398 Q402 T408 Y409 H410	C398-C406 HydrophobicContact CB-CB 3.73Å; C398-C406 WeakPolarHBondContact CB-SG 3.27Å; C398-C406 WeakPolarHBondContact SG-CB 3.21Å; C398-C406 CovalentContact SG-SG 2.02Å; C398-C406 PolarHBondContact SG-SG 3.2Å; Q402-C406 WeakPolarHBondContact O-CB 3.12Å; Q402-C406 PolarHBondContact O-N 3.32Å; C406-T408 VanDerWaalsContact C-N 3.33Å; C406-T408 PolarHBondContact O-N 2.71Å; C406-Y409 WeakPolarHBondContact O-CB 3.37Å; C406-Y409 PolarHBondContact O-N 3.24Å; C406-Y409 WeakPolarHBondContact SG-CB 3.24Å; C406-Y409 PolarHBondContact SG-N 3.37Å; C406-H410 PolarHBondContact O-CD2 3.38Å; C406-H410 PolarHBondContact O-N 3.44Å
407	V	88.4	Confident	87.9	Confident	58 Å²	58	59.5 Å²	59.5	35%	0.352	31%	0.313	S	S	.	.	H	α-helix	trans	-55.3	-47	178.4	-179.3	0	0	0	0	111.7	Y30 T405 Y409 H410 L411	Y30-V407 HydrophobicContact CD1-CB 4.46Å; Y30-V407 HydrophobicContact CD1-CG1 4.06Å; Y30-V407 HydrophobicContact CD1-CG2 3.66Å; Y30-V407 HydrophobicContact CD2-CG1 4.39Å; Y30-V407 HydrophobicContact CE1-CG2 3.6Å; Y30-V407 HydrophobicContact CG-CG1 3.93Å; Y30-V407 HydrophobicContact CG-CG2 4.28Å; T405-V407 PolarHBondContact O-N 3.02Å; T405-V407 VanDerWaalsContact O-N 3.11Å; V407-Y409 VanDerWaalsContact C-N 3.28Å; V407-Y409 PolarHBondContact O-N 3.21Å; V407-H410 PolarHBondContact O-N 3.05Å; V407-L411 HydrophobicContact CG1-CD1 3.86Å; V407-L411 HydrophobicContact CG1-CG 4.29Å; V407-L411 PolarHBondContact O-N 3.5Å
408	T	90.9	Very high	88.2	Confident	83 Å²	83	56.5 Å²	56.5	51%	0.509	29%	0.294	S	S	.	.	H	α-helix	trans	-57.3	-42.2	-179.5	-50.4	0	0	0	0	111.8	F392 V397 C406 Y412	F392-T408 HydrophobicContact CZ-CG2 4.33Å; V397-T408 HydrophobicContact CG1-CG2 3.92Å; C406-T408 VanDerWaalsContact C-N 3.33Å; C406-T408 PolarHBondContact O-N 2.71Å; T408-Y412 WeakPolarHBondContact O-CB 3.24Å; T408-Y412 PolarHBondContact O-N 3.4Å
409	Y	90.2	Very high	88.6	Confident	10 Å²	10	58.4 Å²	58.4	4%	0.039	30%	0.303	C	S	.	.	H	α-helix	trans	-64.4	-47.6	178.4	171	-108.3	0	0	0	111.7	A387 V389 F392 I403 C406 V407 Y412 R413	A387-Y409 VanDerWaalsContact O-CE2 3.31Å; A387-Y409 WeakPolarHBondContact O-CE2 3.48Å; V389-Y409 VanDerWaalsContact CG2-OH 3.22Å; V389-Y409 WeakPolarHBondContact CG2-OH 3.27Å; F392-Y409 HydrophobicContact CB-CD2 4.16Å; F392-Y409 HydrophobicContact CB-CE2 4.27Å; F392-Y409 AromaticContact CD1-CD2 3.61Å; F392-Y409 HydrophobicContact CD1-CD2 3.61Å; F392-Y409 HydrophobicContact CD1-CE2 4.5Å; F392-Y409 HydrophobicContact CD1-CG 4.3Å; F392-Y409 HydrophobicContact CD2-CD2 4.15Å; F392-Y409 AromaticContact CE1-CD2 3.99Å; F392-Y409 HydrophobicContact CE1-CD2 3.99Å; F392-Y409 HydrophobicContact CE1-CG 4.35Å; F392-Y409 HydrophobicContact CE2-CD2 4.48Å; F392-Y409 AromaticContact CG-CD2 3.7Å; F392-Y409 HydrophobicContact CG-CD2 3.7Å; F392-Y409 HydrophobicContact CG-CE2 4.28Å; F392-Y409 HydrophobicContact CZ-CD2 4.4Å; I403-Y409 HydrophobicContact CD1-CD1 3.79Å; I403-Y409 HydrophobicContact CD1-CD2 3.67Å; I403-Y409 HydrophobicContact CD1-CE1 4.29Å; I403-Y409 HydrophobicContact CD1-CE2 4.18Å; I403-Y409 HydrophobicContact CD1-CG 3.45Å; I403-Y409 VanDerWaalsContact CD1-CG 3.45Å; I403-Y409 HydrophobicContact CG1-CD1 3.72Å; I403-Y409 HydrophobicContact CG1-CD2 4.29Å; I403-Y409 HydrophobicContact CG1-CE1 3.88Å; I403-Y409 HydrophobicContact CG1-CE2 4.41Å; I403-Y409 HydrophobicContact CG1-CG 3.95Å; C406-Y409 WeakPolarHBondContact O-CB 3.37Å; C406-Y409 PolarHBondContact O-N 3.24Å; C406-Y409 WeakPolarHBondContact SG-CB 3.24Å; C406-Y409 PolarHBondContact SG-N 3.37Å; V407-Y409 VanDerWaalsContact C-N 3.28Å; V407-Y409 PolarHBondContact O-N 3.21Å; Y409-Y412 PolarHBondContact O-N 3.3Å; Y409-R413 VanDerWaalsContact O-CB 3.23Å; Y409-R413 WeakPolarHBondContact O-CB 3.34Å; Y409-R413 PolarHBondContact O-N 2.84Å; Y409-R413 WeakPolarHBondContact OH-CD 3.39Å; Y409-R413 PolarHBondContact OH-NH1 3.16Å
410	H	89.3	Confident	89.1	Confident	34 Å²	34	56.2 Å²	56.2	16%	0.157	29%	0.287	C	S	.	.	H	α-helix	trans	-65.2	-42.4	-178.7	-72.4	-64.9	0	0	0	112.6	Q404 C406 V407 M414	Q404-H410 PolarHBondContact O-NE2 2.69Å; C406-H410 PolarHBondContact O-CD2 3.38Å; C406-H410 PolarHBondContact O-N 3.44Å; V407-H410 PolarHBondContact O-N 3.05Å; H410-M414 VanDerWaalsContact O-CB 3.25Å; H410-M414 WeakPolarHBondContact O-CB 3.47Å; H410-M414 PolarHBondContact O-N 2.87Å
411	L	91.6	Very high	89.8	Confident	55 Å²	55	52.4 Å²	52.4	29%	0.288	27%	0.268	S	S	.	.	H	α-helix	trans	-64.1	-47.6	175.1	-70.7	177.6	0	0	0	111.3	V34 V407 R413 M414 I415	V34-L411 HydrophobicContact CG2-CD2 4.06Å; V407-L411 HydrophobicContact CG1-CD1 3.86Å; V407-L411 HydrophobicContact CG1-CG 4.29Å; V407-L411 PolarHBondContact O-N 3.5Å; L411-R413 PolarHBondContact O-N 3.44Å; L411-M414 HydrophobicContact CD2-CE 4.35Å; L411-M414 PolarHBondContact O-N 2.82Å; L411-I415 VanDerWaalsContact O-CG1 3.28Å; L411-I415 WeakPolarHBondContact O-CG1 3.32Å; L411-I415 PolarHBondContact O-N 3.18Å
412	Y	93.9	Very high	90.7	Very high	69 Å²	69	50.6 Å²	50.6	27%	0.271	25%	0.253	S	S	.	.	H	α-helix	trans	-59.5	-47.6	178	-175.9	-96.8	0	0	0	111.8	P383 L386 A387 F392 T408 Y409 M414 I415 T416	P383-Y412 PolarHBondContact O-OH 2.64Å; P383-Y412 VanDerWaalsContact O-OH 3.12Å; L386-Y412 HydrophobicContact CB-CE1 4.16Å; L386-Y412 WeakPolarHBondContact CB-OH 3.26Å; A387-Y412 HydrophobicContact CB-CD1 3.73Å; A387-Y412 HydrophobicContact CB-CE1 3.71Å; F392-Y412 HydrophobicContact CD2-CD1 4.04Å; F392-Y412 HydrophobicContact CD2-CE1 4.41Å; F392-Y412 AromaticContact CE2-CD1 3.84Å; F392-Y412 HydrophobicContact CE2-CD1 3.84Å; F392-Y412 HydrophobicContact CE2-CE1 4.46Å; F392-Y412 HydrophobicContact CE2-CG 4Å; T408-Y412 WeakPolarHBondContact O-CB 3.24Å; T408-Y412 PolarHBondContact O-N 3.4Å; Y409-Y412 PolarHBondContact O-N 3.3Å; Y412-M414 PolarHBondContact O-N 3.04Å; Y412-I415 PolarHBondContact O-N 3.23Å; Y412-T416 HydrophobicContact CD1-CG2 4.15Å; Y412-T416 HydrophobicContact CD2-CG2 4.28Å; Y412-T416 HydrophobicContact CE1-CG2 3.78Å; Y412-T416 HydrophobicContact CE2-CG2 3.93Å; Y412-T416 HydrophobicContact CG-CG2 4.39Å; Y412-T416 WeakPolarHBondContact O-CB 3.44Å; Y412-T416 VanDerWaalsContact O-CG2 3.3Å; Y412-T416 WeakPolarHBondContact O-CG2 3.46Å; Y412-T416 PolarHBondContact O-N 3.13Å; Y412-T416 PolarHBondContact O-OG1 3.41Å
413	R	93.1	Very high	91.4	Very high	69 Å²	69	45 Å²	45	26%	0.26	23%	0.227	S	C	.	.	H	α-helix	trans	-61.3	-45.7	178.1	-174.2	178.7	78.3	-167.9	1	111.6	A387 Y409 L411 T416 I417	A387-R413 HydrophobicContact CB-CB 4.34Å; A387-R413 HydrophobicContact CB-CG 4.39Å; Y409-R413 VanDerWaalsContact O-CB 3.23Å; Y409-R413 WeakPolarHBondContact O-CB 3.34Å; Y409-R413 PolarHBondContact O-N 2.84Å; Y409-R413 WeakPolarHBondContact OH-CD 3.39Å; Y409-R413 PolarHBondContact OH-NH1 3.16Å; L411-R413 PolarHBondContact O-N 3.44Å; R413-T416 PolarHBondContact O-N 2.91Å; R413-T416 PolarHBondContact O-OG1 2.94Å; R413-I417 HydrophobicContact CG-CD1 3.56Å; R413-I417 HydrophobicContact CG-CG1 4.2Å; R413-I417 WeakPolarHBondContact O-CB 3.42Å; R413-I417 VanDerWaalsContact O-CG1 3.25Å; R413-I417 WeakPolarHBondContact O-CG1 3.41Å; R413-I417 PolarHBondContact O-N 3.42Å
414	M	92.5	Very high	92.2	Very high	21 Å²	21	44.2 Å²	44.2	10%	0.103	22%	0.223	C	C	.	.	H	α-helix	trans	-59.5	-48.2	178.1	176.9	-80.9	-72.8	0	0	111.2	A37 Y38 H410 L411 Y412 N418	A37-M414 HydrophobicContact CB-CE 4.03Å; A37-M414 HydrophobicContact CB-CG 3.66Å; A37-M414 HydrophobicContact CB-SD 3.4Å; A37-M414 WeakPolarHBondContact CB-SD 3.43Å; Y38-M414 HydrophobicContact CD2-CG 4.47Å; Y38-M414 HydrophobicContact CE2-CB 4.09Å; Y38-M414 HydrophobicContact CE2-CG 4.09Å; H410-M414 VanDerWaalsContact O-CB 3.25Å; H410-M414 WeakPolarHBondContact O-CB 3.47Å; H410-M414 PolarHBondContact O-N 2.87Å; L411-M414 HydrophobicContact CD2-CE 4.35Å; L411-M414 PolarHBondContact O-N 2.82Å; Y412-M414 PolarHBondContact O-N 3.04Å; M414-N418 WeakPolarHBondContact O-CB 3.25Å; M414-N418 PolarHBondContact O-N 3.28Å; M414-N418 PolarHBondContact O-ND2 3.49Å
415	I	95.6	Very high	93.1	Very high	99 Å²	99	39.3 Å²	39.3	51%	0.508	20%	0.202	S	C	.	.	H	α-helix	trans	-62.6	-49	-179.5	-68.7	165.5	0	0	0	110.9	L411 Y412 N418 L419	L411-I415 VanDerWaalsContact O-CG1 3.28Å; L411-I415 WeakPolarHBondContact O-CG1 3.32Å; L411-I415 PolarHBondContact O-N 3.18Å; Y412-I415 PolarHBondContact O-N 3.23Å; I415-N418 PolarHBondContact O-N 2.77Å; I415-L419 WeakPolarHBondContact O-CB 3.47Å; I415-L419 PolarHBondContact O-N 3.38Å
416	T	96	Very high	94	Very high	5 Å²	5	35.8 Å²	35.8	3%	0.031	18%	0.181	C	C	.	.	H	α-helix	trans	-72	-36.3	-173.8	54.3	0	0	0	0	113.3	P383 A387 Y412 R413 L419 A420	P383-T416 HydrophobicContact CB-CG2 3.48Å; P383-T416 VanDerWaalsContact CB-CG2 3.48Å; A387-T416 WeakPolarHBondContact CB-OG1 3.41Å; Y412-T416 HydrophobicContact CD1-CG2 4.15Å; Y412-T416 HydrophobicContact CD2-CG2 4.28Å; Y412-T416 HydrophobicContact CE1-CG2 3.78Å; Y412-T416 HydrophobicContact CE2-CG2 3.93Å; Y412-T416 HydrophobicContact CG-CG2 4.39Å; Y412-T416 WeakPolarHBondContact O-CB 3.44Å; Y412-T416 VanDerWaalsContact O-CG2 3.3Å; Y412-T416 WeakPolarHBondContact O-CG2 3.46Å; Y412-T416 PolarHBondContact O-N 3.13Å; Y412-T416 PolarHBondContact O-OG1 3.41Å; R413-T416 PolarHBondContact O-N 2.91Å; R413-T416 PolarHBondContact O-OG1 2.94Å; T416-L419 PolarHBondContact O-N 3.49Å; T416-A420 PolarHBondContact O-N 2.95Å
417	I	94	Very high	94.4	Very high	18 Å²	18	35.7 Å²	35.7	9%	0.092	18%	0.18	C	C	.	.	H	α-helix	trans	-62.2	-47.9	172.2	-71.7	176.1	0	0	0	110.2	Q384 R413 L419 A420 Q421	Q384-I417 HydrophobicContact CG-CG1 4.4Å; R413-I417 HydrophobicContact CG-CD1 3.56Å; R413-I417 HydrophobicContact CG-CG1 4.2Å; R413-I417 WeakPolarHBondContact O-CB 3.42Å; R413-I417 VanDerWaalsContact O-CG1 3.25Å; R413-I417 WeakPolarHBondContact O-CG1 3.41Å; R413-I417 PolarHBondContact O-N 3.42Å; I417-L419 VanDerWaalsContact C-N 3.32Å; I417-L419 PolarHBondContact O-N 2.86Å; I417-A420 PolarHBondContact O-N 2.96Å; I417-Q421 HydrophobicContact CG2-CG 4.29Å; I417-Q421 VanDerWaalsContact O-CG 3.3Å; I417-Q421 WeakPolarHBondContact O-CG 3.3Å; I417-Q421 PolarHBondContact O-N 2.95Å; I417-Q421 PolarHBondContact O-NE2 3.41Å
418	N	95.7	Very high	94.9	Very high	14 Å²	14	33.8 Å²	33.8	8%	0.075	17%	0.167	C	C	.	.	H	α-helix	trans	-62.1	-39.7	178.6	-83.3	-79.4	0	0	0	112.1	Q42 M414 I415 A420 Q421 F422	Q42-N418 VanDerWaalsContact CA-OD1 3.24Å; Q42-N418 WeakPolarHBondContact CA-OD1 3.32Å; Q42-N418 VanDerWaalsContact CB-OD1 3.27Å; Q42-N418 WeakPolarHBondContact CB-OD1 3.48Å; Q42-N418 PolarHBondContact N-OD1 3.3Å; M414-N418 WeakPolarHBondContact O-CB 3.25Å; M414-N418 PolarHBondContact O-N 3.28Å; M414-N418 PolarHBondContact O-ND2 3.49Å; I415-N418 PolarHBondContact O-N 2.77Å; N418-A420 PolarHBondContact O-N 2.87Å; N418-Q421 PolarHBondContact O-N 3.3Å; N418-F422 WeakPolarHBondContact O-CB 3.41Å; N418-F422 PolarHBondContact O-N 3.19Å
419	L	97.2	Very high	95.2	Very high	63 Å²	63	34.1 Å²	34.1	33%	0.33	16%	0.162	S	C	.	.	H	α-helix	trans	-60.3	-43.8	174.5	-178.9	63.3	0	0	0	111.9	I379 P383 I415 T416 I417 F422 A423	I379-L419 HydrophobicContact CG2-CD1 4.45Å; I379-L419 WeakPolarHBondContact O-CD2 3.23Å; P383-L419 HydrophobicContact CB-CD2 4.47Å; P383-L419 HydrophobicContact CG-CD2 4.08Å; I415-L419 WeakPolarHBondContact O-CB 3.47Å; I415-L419 PolarHBondContact O-N 3.38Å; T416-L419 PolarHBondContact O-N 3.49Å; I417-L419 VanDerWaalsContact C-N 3.32Å; I417-L419 PolarHBondContact O-N 2.86Å; L419-F422 PolarHBondContact O-N 3.12Å; L419-A423 PolarHBondContact O-N 2.95Å
420	A	96.6	Very high	95.5	Very high	0 Å²	0	35.5 Å²	35.5	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-65.8	-43.6	176.5	0	0	0	0	0	112.7	Q384 T416 I417 N418 F422 A423 F424	Q384-A420 HydrophobicContact CB-CB 4.19Å; Q384-A420 HydrophobicContact CG-CB 4.39Å; T416-A420 PolarHBondContact O-N 2.95Å; I417-A420 PolarHBondContact O-N 2.96Å; N418-A420 PolarHBondContact O-N 2.87Å; A420-F422 VanDerWaalsContact C-N 3.29Å; A420-F422 PolarHBondContact O-N 3.01Å; A420-A423 WeakPolarHBondContact O-CB 3.31Å; A420-A423 PolarHBondContact O-N 3.46Å; A420-A423 VanDerWaalsContact O-N 3.14Å; A420-F424 WeakPolarHBondContact O-CD2 3.46Å; A420-F424 WeakPolarHBondContact O-CG 3.2Å; A420-F424 PolarHBondContact O-N 3.33Å
421	Q	97	Very high	95.8	Very high	0 Å²	0	33.9 Å²	33.9	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-63	-38.8	176.5	-58.9	-34	-64.2	0	0	111.4	I45 L84 I417 N418 A423 F424 A425	I45-Q421 HydrophobicContact CG2-CB 3.86Å; L84-Q421 HydrophobicContact CD2-CB 3.9Å; L84-Q421 HydrophobicContact CD2-CG 4.38Å; L84-Q421 VanDerWaalsContact CD2-OE1 3.32Å; I417-Q421 HydrophobicContact CG2-CG 4.29Å; I417-Q421 VanDerWaalsContact O-CG 3.3Å; I417-Q421 WeakPolarHBondContact O-CG 3.3Å; I417-Q421 PolarHBondContact O-N 2.95Å; I417-Q421 PolarHBondContact O-NE2 3.41Å; N418-Q421 PolarHBondContact O-N 3.3Å; Q421-A423 VanDerWaalsContact C-N 3.34Å; Q421-F424 PolarHBondContact O-N 3.38Å; Q421-A425 WeakPolarHBondContact O-CB 3.41Å; Q421-A425 PolarHBondContact O-N 3.17Å
422	F	97	Very high	96	Very high	113 Å²	113	33.2 Å²	33.2	50%	0.496	16%	0.159	S	C	.	.	H	α-helix	trans	-63.1	-40.8	174	-179.1	-96.2	0	0	0	111.9	I45 N418 L419 A420 A425 S426	I45-F422 HydrophobicContact CG2-CB 4.3Å; N418-F422 WeakPolarHBondContact O-CB 3.41Å; N418-F422 PolarHBondContact O-N 3.19Å; L419-F422 PolarHBondContact O-N 3.12Å; A420-F422 VanDerWaalsContact C-N 3.29Å; A420-F422 PolarHBondContact O-N 3.01Å; F422-A425 PolarHBondContact O-N 3.39Å; F422-S426 WeakPolarHBondContact CE1-OG 3.44Å; F422-S426 VanDerWaalsContact O-CB 3.23Å; F422-S426 WeakPolarHBondContact O-CB 3.14Å; F422-S426 PolarHBondContact O-N 2.85Å; F422-S426 PolarHBondContact O-OG 2.63Å
423	A	97.3	Very high	96.1	Very high	4 Å²	4	36.7 Å²	36.7	3%	0.033	18%	0.175	C	C	.	.	H	α-helix	trans	-61.3	-45.4	175.2	0	0	0	0	0	111.8	L376 L419 A420 Q421 S426	L376-A423 HydrophobicContact CD1-CB 4.07Å; L376-A423 WeakPolarHBondContact CD2-O 3.4Å; L376-A423 HydrophobicContact CG-CB 4.11Å; L376-A423 WeakPolarHBondContact O-CB 3.22Å; L419-A423 PolarHBondContact O-N 2.95Å; A420-A423 WeakPolarHBondContact O-CB 3.31Å; A420-A423 PolarHBondContact O-N 3.46Å; A420-A423 VanDerWaalsContact O-N 3.14Å; Q421-A423 VanDerWaalsContact C-N 3.34Å; A423-S426 PolarHBondContact O-N 3.28Å
424	F	96.9	Very high	96.1	Very high	4 Å²	4	37.1 Å²	37.1	2%	0.018	18%	0.182	C	C	.	.	H	α-helix	trans	-62	-42.7	174.7	-63.6	-40.1	0	0	0	112.6	N53 D80 T83 L84 E125 F377 Q381 A420 Q421 S426 T427	N53-F424 PolarHBondContact ND2-O 3.34Å; D80-F424 HydrophobicContact CB-CB 4.43Å; T83-F424 HydrophobicContact CG2-CD2 4.27Å; T83-F424 HydrophobicContact CG2-CE2 3.87Å; L84-F424 HydrophobicContact CD1-CB 3.87Å; L84-F424 HydrophobicContact CD2-CB 4.18Å; L84-F424 HydrophobicContact CD2-CD2 4.48Å; L84-F424 HydrophobicContact CG-CB 4.16Å; E125-F424 HydrophobicContact CG-CE2 4.45Å; E125-F424 HydrophobicContact CG-CZ 4.32Å; F377-F424 HydrophobicContact CD2-CE1 4.26Å; F377-F424 HydrophobicContact CE2-CE1 4.24Å; Q381-F424 VanDerWaalsContact NE2-CZ 3.29Å; A420-F424 WeakPolarHBondContact O-CD2 3.46Å; A420-F424 WeakPolarHBondContact O-CG 3.2Å; A420-F424 PolarHBondContact O-N 3.33Å; Q421-F424 PolarHBondContact O-N 3.38Å; F424-S426 VanDerWaalsContact C-N 3.25Å; F424-S426 PolarHBondContact O-N 3.43Å; F424-T427 PolarHBondContact O-OG1 3.06Å
425	A	97.5	Very high	96.1	Very high	8 Å²	8	36.5 Å²	36.5	7%	0.066	18%	0.179	C	C	.	.	H	α-helix	trans	-63.6	-32.8	176.5	0	0	0	0	0	112.3	I45 G49 Q421 F422 T427	I45-A425 HydrophobicContact CG2-CB 4.39Å; G49-A425 VanDerWaalsContact CA-CB 3.42Å; Q421-A425 WeakPolarHBondContact O-CB 3.41Å; Q421-A425 PolarHBondContact O-N 3.17Å; F422-A425 PolarHBondContact O-N 3.39Å; A425-T427 VanDerWaalsContact C-N 3.35Å; A425-T427 PolarHBondContact O-N 2.89Å
426	S	97.2	Very high	95.9	Very high	15 Å²	15	39 Å²	39	11%	0.105	18%	0.182	C	C	.	.	H	α-helix	trans	-80.3	-10.5	-172.4	-66.3	0	0	0	0	114.6	F422 A423 F424 F428 F429 L430	F422-S426 WeakPolarHBondContact CE1-OG 3.44Å; F422-S426 VanDerWaalsContact O-CB 3.23Å; F422-S426 WeakPolarHBondContact O-CB 3.14Å; F422-S426 PolarHBondContact O-N 2.85Å; F422-S426 PolarHBondContact O-OG 2.63Å; A423-S426 PolarHBondContact O-N 3.28Å; F424-S426 VanDerWaalsContact C-N 3.25Å; F424-S426 PolarHBondContact O-N 3.43Å; S426-F428 PolarHBondContact O-N 3.34Å; S426-F429 PolarHBondContact O-N 3.21Å; S426-F429 VanDerWaalsContact O-N 3.12Å; S426-L430 PolarHBondContact O-N 2.92Å
427	T	95.7	Very high	95.8	Very high	8 Å²	8	41.8 Å²	41.8	5%	0.049	20%	0.197	C	C	.	.	H	α-helix	trans	-58.3	-36.8	178.8	59.4	0	0	0	0	112.4	N53 N56 L376 F424 A425 F429 L430 Y431	N53-T427 PolarHBondContact OD1-OG1 3.45Å; N53-T427 VanDerWaalsContact OD1-OG1 3.14Å; N56-T427 PolarHBondContact ND2-OG1 3.01Å; L376-T427 HydrophobicContact CD2-CG2 4.35Å; F424-T427 PolarHBondContact O-OG1 3.06Å; A425-T427 VanDerWaalsContact C-N 3.35Å; A425-T427 PolarHBondContact O-N 2.89Å; T427-F429 VanDerWaalsContact C-N 3.31Å; T427-F429 PolarHBondContact O-N 3.48Å; T427-L430 WeakPolarHBondContact O-CB 3.49Å; T427-L430 PolarHBondContact O-N 3.15Å; T427-Y431 WeakPolarHBondContact O-CD2 3.31Å; T427-Y431 PolarHBondContact O-N 3.26Å; T427-Y431 VanDerWaalsContact O-N 3.1Å
428	F	97.8	Very high	95.8	Very high	17 Å²	17	41 Å²	41	8%	0.075	19%	0.193	C	C	.	.	H	α-helix	trans	-54.5	-45.2	175.1	170.5	-92.4	0	0	0	112.3	L52 I55 N56 S426 L430 Y431 L432 F438 L442	L52-F428 HydrophobicContact CB-CB 3.8Å; L52-F428 HydrophobicContact CB-CD2 4.46Å; L52-F428 HydrophobicContact CB-CG 4.04Å; L52-F428 HydrophobicContact CD1-CB 4.29Å; L52-F428 HydrophobicContact CD1-CD1 4.18Å; L52-F428 HydrophobicContact CD1-CG 4.41Å; L52-F428 HydrophobicContact CD2-CD1 3.74Å; L52-F428 HydrophobicContact CD2-CD2 4.28Å; L52-F428 HydrophobicContact CD2-CE1 3.95Å; L52-F428 HydrophobicContact CD2-CG 3.93Å; L52-F428 HydrophobicContact CD2-CZ 4.34Å; L52-F428 HydrophobicContact CG-CB 4.43Å; L52-F428 HydrophobicContact CG-CD1 4.37Å; L52-F428 HydrophobicContact CG-CG 4.34Å; I55-F428 HydrophobicContact CB-CE2 4.33Å; I55-F428 HydrophobicContact CG2-CD2 4.3Å; I55-F428 HydrophobicContact CG2-CE2 3.74Å; N56-F428 WeakPolarHBondContact ND2-CA 3.11Å; N56-F428 PolarHBondContact ND2-N 3.04Å; N56-F428 WeakPolarHBondContact OD1-CA 3.43Å; N56-F428 WeakPolarHBondContact OD1-CD2 3.4Å; S426-F428 PolarHBondContact O-N 3.34Å; F428-L430 VanDerWaalsContact C-N 3.32Å; F428-L430 PolarHBondContact O-N 3.42Å; F428-Y431 PolarHBondContact O-N 3.19Å; F428-Y431 VanDerWaalsContact O-N 3.16Å; F428-L432 HydrophobicContact CE1-CB 4.3Å; F428-L432 HydrophobicContact CE1-CD2 3.94Å; F428-L432 HydrophobicContact CZ-CD1 4.26Å; F428-L432 HydrophobicContact CZ-CD2 4.35Å; F428-L432 WeakPolarHBondContact O-CB 3.4Å; F428-L432 PolarHBondContact O-N 3.22Å; F428-F438 HydrophobicContact CD2-CE1 4.4Å; F428-F438 HydrophobicContact CD2-CZ 4.18Å; F428-F438 HydrophobicContact CE2-CE1 4.07Å; F428-F438 HydrophobicContact CE2-CZ 4.15Å; F428-L442 HydrophobicContact CE2-CD2 4.21Å; F428-L442 HydrophobicContact CZ-CD2 4.18Å
429	F	97.3	Very high	95.8	Very high	91 Å²	91	45.1 Å²	45.1	40%	0.399	21%	0.208	S	C	.	.	H	α-helix	trans	-67.1	-35.5	-178.2	-64.5	-69.2	0	0	0	111.8	L52 S426 T427 Y431 L432 F433	L52-F429 HydrophobicContact CD1-CE2 3.72Å; L52-F429 HydrophobicContact CD1-CZ 3.89Å; S426-F429 PolarHBondContact O-N 3.21Å; S426-F429 VanDerWaalsContact O-N 3.12Å; T427-F429 VanDerWaalsContact C-N 3.31Å; T427-F429 PolarHBondContact O-N 3.48Å; F429-Y431 VanDerWaalsContact C-N 3.34Å; F429-Y431 PolarHBondContact O-N 3.2Å; F429-L432 PolarHBondContact O-N 3.09Å; F429-F433 HydrophobicContact CB-CD2 4.13Å; F429-F433 HydrophobicContact CB-CE2 3.92Å; F429-F433 HydrophobicContact CD1-CE2 4.14Å; F429-F433 HydrophobicContact CG-CE2 4.45Å; F429-F433 WeakPolarHBondContact O-CB 3.44Å; F429-F433 WeakPolarHBondContact O-CD2 3.25Å; F429-F433 WeakPolarHBondContact O-CG 3.22Å; F429-F433 PolarHBondContact O-N 2.85Å
430	L	95.7	Very high	95.7	Very high	39 Å²	39	45.8 Å²	45.8	20%	0.204	21%	0.209	C	C	.	.	H	α-helix	trans	-61.6	-44.1	172.3	-66.8	-179.4	0	0	0	111.3	L369 A372 V373 L376 S426 T427 F428 L434	L369-L430 HydrophobicContact CD1-CB 4.18Å; L369-L430 WeakPolarHBondContact CD1-O 3.14Å; A372-L430 HydrophobicContact CB-CD1 4.19Å; A372-L430 HydrophobicContact CB-CD2 4.1Å; V373-L430 HydrophobicContact CB-CD1 4.42Å; V373-L430 HydrophobicContact CG2-CB 4.39Å; V373-L430 HydrophobicContact CG2-CD1 3.91Å; L376-L430 HydrophobicContact CB-CD1 4.08Å; L376-L430 HydrophobicContact CD2-CD1 3.54Å; L376-L430 HydrophobicContact CD2-CG 4.21Å; L376-L430 HydrophobicContact CG-CD1 4.47Å; S426-L430 PolarHBondContact O-N 2.92Å; T427-L430 WeakPolarHBondContact O-CB 3.49Å; T427-L430 PolarHBondContact O-N 3.15Å; F428-L430 VanDerWaalsContact C-N 3.32Å; F428-L430 PolarHBondContact O-N 3.42Å; L430-L434 HydrophobicContact CD2-CD1 4.25Å; L430-L434 VanDerWaalsContact O-CB 3.28Å; L430-L434 WeakPolarHBondContact O-CB 3.28Å; L430-L434 PolarHBondContact O-N 3Å
431	Y	96	Very high	95.5	Very high	0 Å²	0	46.5 Å²	46.5	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-65.4	-43.7	176.2	-55.8	-35.9	0	0	0	111.9	N56 F60 M73 L369 V373 T427 F428 F429 F433 N435	N56-Y431 HydrophobicContact CB-CD2 4.4Å; N56-Y431 WeakPolarHBondContact OD1-CD2 3.3Å; F60-Y431 HydrophobicContact CE2-CD1 4.47Å; F60-Y431 AromaticContact CE2-CD2 3.61Å; F60-Y431 HydrophobicContact CE2-CD2 3.61Å; F60-Y431 AromaticContact CE2-CE2 3.68Å; F60-Y431 HydrophobicContact CE2-CE2 3.68Å; F60-Y431 HydrophobicContact CE2-CG 4.04Å; F60-Y431 HydrophobicContact CZ-CD1 4.01Å; F60-Y431 AromaticContact CZ-CD2 3.87Å; F60-Y431 HydrophobicContact CZ-CD2 3.87Å; F60-Y431 HydrophobicContact CZ-CE1 4.37Å; F60-Y431 HydrophobicContact CZ-CE2 4.18Å; F60-Y431 AromaticContact CZ-CG 3.78Å; F60-Y431 HydrophobicContact CZ-CG 3.78Å; M73-Y431 HydrophobicContact CE-CD1 3.54Å; M73-Y431 HydrophobicContact CE-CE1 2.99Å; M73-Y431 HydrophobicContact CE-CE2 4.4Å; M73-Y431 HydrophobicContact CE-CG 4.47Å; M73-Y431 VanDerWaalsContact CE-CZ 3.49Å; L369-Y431 HydrophobicContact CD1-CD1 3.68Å; L369-Y431 HydrophobicContact CD1-CE1 4.13Å; L369-Y431 HydrophobicContact CD2-CD1 4.09Å; L369-Y431 HydrophobicContact CG-CD1 4.27Å; L369-Y431 HydrophobicContact CG-CE1 4.49Å; V373-Y431 HydrophobicContact CG2-CD1 4.41Å; V373-Y431 HydrophobicContact CG2-CE1 3.51Å; T427-Y431 WeakPolarHBondContact O-CD2 3.31Å; T427-Y431 PolarHBondContact O-N 3.26Å; T427-Y431 VanDerWaalsContact O-N 3.1Å; F428-Y431 PolarHBondContact O-N 3.19Å; F428-Y431 VanDerWaalsContact O-N 3.16Å; F429-Y431 VanDerWaalsContact C-N 3.34Å; F429-Y431 PolarHBondContact O-N 3.2Å; Y431-F433 PolarHBondContact O-N 3.35Å; Y431-N435 WeakPolarHBondContact O-CA 3.21Å; Y431-N435 WeakPolarHBondContact O-CB 3.48Å; Y431-N435 PolarHBondContact O-N 3.17Å
432	L	96.4	Very high	95.4	Very high	41 Å²	41	47.8 Å²	47.8	22%	0.215	22%	0.22	C	C	.	.	H	α-helix	trans	-59.3	-48.6	177.5	-173	72.4	0	0	0	111.3	F428 F429 R439 L442	F428-L432 HydrophobicContact CE1-CB 4.3Å; F428-L432 HydrophobicContact CE1-CD2 3.94Å; F428-L432 HydrophobicContact CZ-CD1 4.26Å; F428-L432 HydrophobicContact CZ-CD2 4.35Å; F428-L432 WeakPolarHBondContact O-CB 3.4Å; F428-L432 PolarHBondContact O-N 3.22Å; F429-L432 PolarHBondContact O-N 3.09Å; L432-R439 HydrophobicContact CD1-CG 4.16Å; L432-R439 WeakPolarHBondContact O-CD 3.5Å; L432-R439 WeakPolarHBondContact O-CG 3.12Å; L432-R439 PolarHBondContact O-NH1 2.97Å; L432-L442 HydrophobicContact CD1-CD2 3.93Å
433	F	95	Very high	95.2	Very high	142 Å²	142	51.4 Å²	51.4	62%	0.623	23%	0.23	S	C	*	.	H	α-helix	trans	-82.3	-38.5	-173.7	-63.5	-50.4	0	0	0	113.5	F429 Y431 R439	F429-F433 HydrophobicContact CB-CD2 4.13Å; F429-F433 HydrophobicContact CB-CE2 3.92Å; F429-F433 HydrophobicContact CD1-CE2 4.14Å; F429-F433 HydrophobicContact CG-CE2 4.45Å; F429-F433 WeakPolarHBondContact O-CB 3.44Å; F429-F433 WeakPolarHBondContact O-CD2 3.25Å; F429-F433 WeakPolarHBondContact O-CG 3.22Å; F429-F433 PolarHBondContact O-N 2.85Å; Y431-F433 PolarHBondContact O-N 3.35Å; F433-R439 VanDerWaalsContact C-NH1 3.32Å; F433-R439 PolarHBondContact O-NH1 3.34Å
434	L	92.9	Very high	94.9	Very high	77 Å²	77	55.8 Å²	55.8	40%	0.403	25%	0.249	S	C	.	.	H	α-helix	trans	-97.3	-20.2	-171.9	-56	177.3	0	0	0	113.8	L369 A372 L430	L369-L434 HydrophobicContact CB-CB 4.21Å; L369-L434 HydrophobicContact CD1-CB 3.8Å; L369-L434 HydrophobicContact CD1-CD1 4.18Å; A372-L434 HydrophobicContact CB-CD1 3.94Å; L430-L434 HydrophobicContact CD2-CD1 4.25Å; L430-L434 VanDerWaalsContact O-CB 3.28Å; L430-L434 WeakPolarHBondContact O-CB 3.28Å; L430-L434 PolarHBondContact O-N 3Å
435	N	93.4	Very high	94.5	Very high	8 Å²	8	57.6 Å²	57.6	4%	0.043	26%	0.258	C	S	.	.			trans	-107	102.1	-178	-168.8	-15.9	0	0	0	112.3	Y70 L369 Y431 D437 F438 R439	Y70-N435 WeakPolarHBondContact CE1-ND2 3.49Å; L369-N435 HydrophobicContact CD2-CB 3.9Å; Y431-N435 WeakPolarHBondContact O-CA 3.21Å; Y431-N435 WeakPolarHBondContact O-CB 3.48Å; Y431-N435 PolarHBondContact O-N 3.17Å; N435-D437 VanDerWaalsContact C-N 3.34Å; N435-D437 PolarHBondContact O-N 3.05Å; N435-D437 WeakPolarHBondContact OD1-CB 3.38Å; N435-D437 PolarHBondContact OD1-N 3.27Å; N435-D437 VanDerWaalsContact OD1-N 3.09Å; N435-F438 HydrophobicContact CB-CB 3.65Å; N435-F438 WeakPolarHBondContact O-CB 3.17Å; N435-F438 PolarHBondContact O-N 3.5Å; N435-F438 PolarHBondContact OD1-N 2.76Å; N435-F438 VanDerWaalsContact OD1-N 3.16Å; N435-R439 PolarHBondContact O-N 3.24Å
436	R	92.2	Very high	94.2	Very high	152 Å²	152	60.4 Å²	60.4	57%	0.574	28%	0.276	S	S	*	.	H	α-helix	trans	-59.8	-42.7	176.7	178.5	178	171.1	170.9	-2.1	112.3	F438 R439 E440	R436-F438 VanDerWaalsContact C-N 3.26Å; R436-F438 PolarHBondContact O-N 2.91Å; R436-R439 PolarHBondContact O-N 3.38Å; R436-E440 IonicContact CZ-OE1 2.75Å; R436-E440 IonicContact NE-OE1 3.12Å; R436-E440 PolarHBondContact NE-OE1 2.84Å; R436-E440 IonicContact NH2-OE1 3.96Å; R436-E440 PolarHBondContact NH2-OE1 3.4Å; R436-E440 WeakPolarHBondContact O-CG 3.43Å; R436-E440 PolarHBondContact O-N 2.93Å
437	D	92.4	Very high	93.7	Very high	64 Å²	64	61.4 Å²	61.4	34%	0.342	28%	0.283	S	S	.	.	H	α-helix	trans	-65.1	-34.4	-178.8	-69.8	-52.1	0	0	0	111.8	K64 F65 N435 T441	K64-D437 WeakPolarHBondContact CE-OD1 3.4Å; K64-D437 IonicContact NZ-OD1 2.79Å; K64-D437 PolarHBondContact NZ-OD1 3.23Å; F65-D437 HydrophobicContact CE1-CB 3.99Å; F65-D437 HydrophobicContact CZ-CB 4.11Å; N435-D437 VanDerWaalsContact C-N 3.34Å; N435-D437 PolarHBondContact O-N 3.05Å; N435-D437 WeakPolarHBondContact OD1-CB 3.38Å; N435-D437 PolarHBondContact OD1-N 3.27Å; N435-D437 VanDerWaalsContact OD1-N 3.09Å; D437-T441 WeakPolarHBondContact O-CB 3.32Å; D437-T441 PolarHBondContact O-N 2.98Å; D437-T441 PolarHBondContact O-OG1 3.22Å
438	F	95.4	Very high	92.9	Very high	0 Å²	0	67.6 Å²	67.6	0%	0	31%	0.306	C	S	.	.	H	α-helix	trans	-62.1	-50.8	173.6	-176.3	-89	0	0	0	110.9	N56 V59 F60 F65 F428 N435 R436 E440 T441 L442	N56-F438 VanDerWaalsContact OD1-CZ 3.3Å; N56-F438 WeakPolarHBondContact OD1-CZ 3.21Å; V59-F438 HydrophobicContact CB-CD2 3.98Å; V59-F438 HydrophobicContact CB-CE2 3.56Å; V59-F438 HydrophobicContact CB-CZ 4.15Å; V59-F438 HydrophobicContact CG1-CD2 3.37Å; V59-F438 HydrophobicContact CG1-CE2 3.53Å; V59-F438 HydrophobicContact CG1-CG 4.04Å; V59-F438 HydrophobicContact CG1-CZ 4.29Å; V59-F438 HydrophobicContact CG2-CE2 4Å; V59-F438 HydrophobicContact CG2-CZ 4.06Å; F60-F438 HydrophobicContact CD1-CD2 4.39Å; F60-F438 HydrophobicContact CD2-CE2 4.44Å; F60-F438 AromaticContact CE1-CD2 3.75Å; F60-F438 HydrophobicContact CE1-CD2 3.75Å; F60-F438 HydrophobicContact CE1-CE2 4.33Å; F60-F438 HydrophobicContact CE2-CD2 4.16Å; F60-F438 AromaticContact CE2-CE2 3.95Å; F60-F438 HydrophobicContact CE2-CE2 3.95Å; F60-F438 AromaticContact CZ-CD2 3.6Å; F60-F438 HydrophobicContact CZ-CD2 3.6Å; F60-F438 AromaticContact CZ-CE2 3.87Å; F60-F438 HydrophobicContact CZ-CE2 3.87Å; F65-F438 HydrophobicContact CZ-CB 4.38Å; F428-F438 HydrophobicContact CD2-CE1 4.4Å; F428-F438 HydrophobicContact CD2-CZ 4.18Å; F428-F438 HydrophobicContact CE2-CE1 4.07Å; F428-F438 HydrophobicContact CE2-CZ 4.15Å; N435-F438 HydrophobicContact CB-CB 3.65Å; N435-F438 WeakPolarHBondContact O-CB 3.17Å; N435-F438 PolarHBondContact O-N 3.5Å; N435-F438 PolarHBondContact OD1-N 2.76Å; N435-F438 VanDerWaalsContact OD1-N 3.16Å; R436-F438 VanDerWaalsContact C-N 3.26Å; R436-F438 PolarHBondContact O-N 2.91Å; F438-E440 PolarHBondContact O-N 3.47Å; F438-T441 PolarHBondContact O-N 3.14Å; F438-L442 HydrophobicContact CE1-CD2 4.13Å; F438-L442 WeakPolarHBondContact O-CB 3.48Å; F438-L442 PolarHBondContact O-N 3.47Å
439	R	95.6	Very high	92.1	Very high	102 Å²	102	73.6 Å²	73.6	39%	0.385	34%	0.338	S	S	.	.	H	α-helix	trans	-58.5	-44.7	178	-69.2	-167.1	-65.5	-88.7	9.3	113.2	L432 F433 N435 R436 T441 L442 R443	L432-R439 HydrophobicContact CD1-CG 4.16Å; L432-R439 WeakPolarHBondContact O-CD 3.5Å; L432-R439 WeakPolarHBondContact O-CG 3.12Å; L432-R439 PolarHBondContact O-NH1 2.97Å; F433-R439 VanDerWaalsContact C-NH1 3.32Å; F433-R439 PolarHBondContact O-NH1 3.34Å; N435-R439 PolarHBondContact O-N 3.24Å; R436-R439 PolarHBondContact O-N 3.38Å; R439-T441 VanDerWaalsContact C-N 3.32Å; R439-T441 PolarHBondContact O-N 3.24Å; R439-L442 PolarHBondContact O-N 3.32Å; R439-R443 WeakPolarHBondContact O-CB 3.4Å; R439-R443 PolarHBondContact O-N 3.32Å
440	E	93.7	Very high	91.2	Very high	77 Å²	77	71.7 Å²	71.7	36%	0.36	34%	0.335	S	S	.	.	H	α-helix	trans	-62.9	-41.8	179	-72.2	173.8	-177.6	0	0	111.3	K64 R436 F438 F444	K64-E440 IonicContact NZ-OE2 2.67Å; K64-E440 PolarHBondContact NZ-OE2 2.95Å; K64-E440 VanDerWaalsContact NZ-OE2 3.11Å; R436-E440 IonicContact CZ-OE1 2.75Å; R436-E440 IonicContact NE-OE1 3.12Å; R436-E440 PolarHBondContact NE-OE1 2.84Å; R436-E440 IonicContact NH2-OE1 3.96Å; R436-E440 PolarHBondContact NH2-OE1 3.4Å; R436-E440 WeakPolarHBondContact O-CG 3.43Å; R436-E440 PolarHBondContact O-N 2.93Å; F438-E440 PolarHBondContact O-N 3.47Å; E440-F444 WeakPolarHBondContact O-CB 3.33Å; E440-F444 PolarHBondContact O-N 3.21Å
441	T	93.8	Very high	90.2	Very high	14 Å²	14	77.2 Å²	77.2	9%	0.086	36%	0.36	C	S	.	.	H	α-helix	trans	-70.3	-42.3	178.6	-50.9	0	0	0	0	111.5	V59 C62 F65 D437 F438 R439 R443 F444 I445	V59-T441 HydrophobicContact CG1-CG2 4.05Å; C62-T441 HydrophobicContact CB-CG2 4.13Å; F65-T441 HydrophobicContact CE2-CG2 3.97Å; F65-T441 WeakPolarHBondContact CE2-OG1 3.42Å; D437-T441 WeakPolarHBondContact O-CB 3.32Å; D437-T441 PolarHBondContact O-N 2.98Å; D437-T441 PolarHBondContact O-OG1 3.22Å; F438-T441 PolarHBondContact O-N 3.14Å; R439-T441 VanDerWaalsContact C-N 3.32Å; R439-T441 PolarHBondContact O-N 3.24Å; T441-R443 PolarHBondContact O-N 3.22Å; T441-F444 WeakPolarHBondContact O-CB 3.48Å; T441-F444 PolarHBondContact O-N 3.14Å; T441-I445 HydrophobicContact CG2-CD1 3.99Å; T441-I445 HydrophobicContact CG2-CG1 4.47Å; T441-I445 WeakPolarHBondContact O-CG1 3.34Å; T441-I445 PolarHBondContact O-N 3.33Å
442	L	94.7	Very high	89.2	Confident	27 Å²	27	85.5 Å²	85.5	14%	0.141	40%	0.396	C	S	.	.	H	α-helix	trans	-59.9	-47.1	174.8	-179.6	61.6	0	0	0	110.7	I55 V59 F428 L432 F438 R439 F444 I445 C446	I55-L442 HydrophobicContact CG2-CD1 3.64Å; V59-L442 HydrophobicContact CG2-CB 4.12Å; V59-L442 HydrophobicContact CG2-CD1 3.88Å; F428-L442 HydrophobicContact CE2-CD2 4.21Å; F428-L442 HydrophobicContact CZ-CD2 4.18Å; L432-L442 HydrophobicContact CD1-CD2 3.93Å; F438-L442 HydrophobicContact CE1-CD2 4.13Å; F438-L442 WeakPolarHBondContact O-CB 3.48Å; F438-L442 PolarHBondContact O-N 3.47Å; R439-L442 PolarHBondContact O-N 3.32Å; L442-F444 VanDerWaalsContact C-N 3.3Å; L442-F444 PolarHBondContact O-N 3.07Å; L442-I445 PolarHBondContact O-N 3.46Å; L442-C446 WeakPolarHBondContact O-CB 3.49Å; L442-C446 PolarHBondContact O-N 3.27Å; L442-C446 PolarHBondContact O-SG 3.2Å
443	R	93.4	Very high	88	Confident	190 Å²	190	85.6 Å²	85.6	72%	0.717	40%	0.4	S	S	*	.	H	α-helix	trans	-57.5	-44.8	174.8	-175	178.6	-177.8	177	2	111.2	R439 T441 C446 C447	R439-R443 WeakPolarHBondContact O-CB 3.4Å; R439-R443 PolarHBondContact O-N 3.32Å; T441-R443 PolarHBondContact O-N 3.22Å; R443-C446 PolarHBondContact O-N 3.23Å; R443-C447 VanDerWaalsContact O-CB 3.24Å; R443-C447 WeakPolarHBondContact O-CB 3.22Å; R443-C447 PolarHBondContact O-N 3.3Å; R443-C447 PolarHBondContact O-SG 3.39Å
444	F	89.8	Confident	86.8	Confident	95 Å²	95	85.4 Å²	85.4	42%	0.417	40%	0.398	S	S	.	.	H	α-helix	trans	-62.3	-44.3	177.5	178.1	-102	0	0	0	112.8	E440 T441 L442 C447 R448	E440-F444 WeakPolarHBondContact O-CB 3.33Å; E440-F444 PolarHBondContact O-N 3.21Å; T441-F444 WeakPolarHBondContact O-CB 3.48Å; T441-F444 PolarHBondContact O-N 3.14Å; L442-F444 VanDerWaalsContact C-N 3.3Å; L442-F444 PolarHBondContact O-N 3.07Å; F444-C447 PolarHBondContact O-N 3.43Å; F444-R448 HydrophobicContact CE1-CG 4.4Å; F444-R448 HydrophobicContact CZ-CG 4.3Å; F444-R448 PolarHBondContact O-N 2.92Å
445	I	89.4	Confident	85.9	Confident	42 Å²	42	86.2 Å²	86.2	22%	0.215	40%	0.402	C	S	.	.	H	α-helix	trans	-62.7	-48.6	176.4	-67.9	166.7	0	0	0	110.2	V59 T441 L442 C447 R448 L449	V59-I445 HydrophobicContact CG2-CD1 4.07Å; T441-I445 HydrophobicContact CG2-CD1 3.99Å; T441-I445 HydrophobicContact CG2-CG1 4.47Å; T441-I445 WeakPolarHBondContact O-CG1 3.34Å; T441-I445 PolarHBondContact O-N 3.33Å; L442-I445 PolarHBondContact O-N 3.46Å; I445-C447 VanDerWaalsContact C-N 3.34Å; I445-C447 PolarHBondContact O-N 3.27Å; I445-R448 PolarHBondContact O-N 2.8Å; I445-L449 HydrophobicContact CG2-CD1 4.07Å; I445-L449 WeakPolarHBondContact O-CG 2.88Å; I445-L449 PolarHBondContact O-N 3.14Å
446	C	89.8	Confident	85	Confident	67 Å²	67	88.6 Å²	88.6	45%	0.453	42%	0.419	S	S	.	.	H	α-helix	trans	-62.2	-39	176.8	-66.4	0	0	0	0	112.4	L442 R443 L449 C450	L442-C446 WeakPolarHBondContact O-CB 3.49Å; L442-C446 PolarHBondContact O-N 3.27Å; L442-C446 PolarHBondContact O-SG 3.2Å; R443-C446 PolarHBondContact O-N 3.23Å; C446-L449 PolarHBondContact O-N 3.11Å; C446-C450 WeakPolarHBondContact O-CB 3.28Å; C446-C450 PolarHBondContact O-N 3.48Å
447	C	86.6	Confident	83.9	Confident	37 Å²	37	84.5 Å²	84.5	25%	0.25	41%	0.407	C	S	.	.	H	α-helix	trans	-64.6	-40.1	174	-77.1	0	0	0	0	111.6	R443 F444 I445 L449 C450 C453	R443-C447 VanDerWaalsContact O-CB 3.24Å; R443-C447 WeakPolarHBondContact O-CB 3.22Å; R443-C447 PolarHBondContact O-N 3.3Å; R443-C447 PolarHBondContact O-SG 3.39Å; F444-C447 PolarHBondContact O-N 3.43Å; I445-C447 VanDerWaalsContact C-N 3.34Å; I445-C447 PolarHBondContact O-N 3.27Å; C447-L449 VanDerWaalsContact C-N 3.34Å; C447-L449 PolarHBondContact O-N 3.31Å; C447-C450 WeakPolarHBondContact O-CB 3.12Å; C447-C450 PolarHBondContact O-N 3.06Å; C447-C450 VanDerWaalsContact O-N 3.1Å; C447-C450 VanDerWaalsContact O-O 3.1Å; C447-C453 HydrophobicContact CB-CB 4.12Å; C447-C453 WeakPolarHBondContact O-CB 3.43Å
448	R	80.3	Confident	83.2	Confident	138 Å²	138	84.9 Å²	84.9	52%	0.521	41%	0.411	S	S	.	.	H	α-helix	trans	-66.7	-35.1	174.9	-82.1	-171.5	162.6	-168.5	-0.3	113.4	F444 I445 C450	F444-R448 HydrophobicContact CE1-CG 4.4Å; F444-R448 HydrophobicContact CZ-CG 4.3Å; F444-R448 PolarHBondContact O-N 2.92Å; I445-R448 PolarHBondContact O-N 2.8Å; R448-C450 VanDerWaalsContact C-N 3.25Å
449	L	80.9	Confident	82.5	Confident	143 Å²	143	88.9 Å²	88.9	75%	0.749	43%	0.433	S	S	*	.	H	α-helix	trans	-70.3	-25.4	171.8	-67.2	169.3	0	0	0	111.6	I445 C446 C447 Q451	I445-L449 HydrophobicContact CG2-CD1 4.07Å; I445-L449 WeakPolarHBondContact O-CG 2.88Å; I445-L449 PolarHBondContact O-N 3.14Å; C446-L449 PolarHBondContact O-N 3.11Å; C447-L449 VanDerWaalsContact C-N 3.34Å; C447-L449 PolarHBondContact O-N 3.31Å; L449-Q451 PolarHBondContact O-N 2.88Å
450	C	78.2	Confident	81.7	Confident	51 Å²	51	89.2 Å²	89.2	35%	0.345	44%	0.439	S	S	.	.			trans	-76.1	113	177.1	-175.7	0	0	0	0	111.5	C446 C447 R448 K452 C453 K454	C446-C450 WeakPolarHBondContact O-CB 3.28Å; C446-C450 PolarHBondContact O-N 3.48Å; C447-C450 WeakPolarHBondContact O-CB 3.12Å; C447-C450 PolarHBondContact O-N 3.06Å; C447-C450 VanDerWaalsContact O-N 3.1Å; C447-C450 VanDerWaalsContact O-O 3.1Å; R448-C450 VanDerWaalsContact C-N 3.25Å; C450-K452 PolarHBondContact O-N 3.4Å; C450-C453 HydrophobicContact CB-CB 4.27Å; C450-C453 PolarHBondContact O-N 3.28Å; C450-C453 VanDerWaalsContact O-N 3.09Å; C450-K454 PolarHBondContact O-N 3.46Å; C450-K454 VanDerWaalsContact O-N 3.09Å
451	Q	74.4	Confident	80.9	Confident	155 Å²	155	92.3 Å²	92.3	72%	0.724	45%	0.447	S	S	*	.	H	α-helix	trans	-55.6	-36.7	179.9	-153.3	172	7.7	0	0	112.7	L449 K454 I455	L449-Q451 PolarHBondContact O-N 2.88Å; Q451-K454 PolarHBondContact O-N 2.96Å; Q451-I455 WeakPolarHBondContact O-CG1 3.45Å; Q451-I455 PolarHBondContact O-N 3.25Å
452	K	74.5	Confident	80.3	Confident	174 Å²	174	95.8 Å²	95.8	76%	0.757	47%	0.465	S	S	*	.	H	α-helix	trans	-63.2	-42.6	177	-67.1	-174.8	178.1	-178.4	0	112.8	C450 S456	C450-K452 PolarHBondContact O-N 3.4Å; K452-S456 PolarHBondContact O-N 3.01Å; K452-S456 VanDerWaalsContact O-N 3.07Å
453	C	71.4	Confident	79.6	Confident	43 Å²	43	99.8 Å²	99.8	29%	0.291	49%	0.486	S	S	.	.	H	α-helix	trans	-71	-36.7	177.8	-72.3	0	0	0	0	111.6	C447 C450 I455 S456 E457	C447-C453 HydrophobicContact CB-CB 4.12Å; C447-C453 WeakPolarHBondContact O-CB 3.43Å; C450-C453 HydrophobicContact CB-CB 4.27Å; C450-C453 PolarHBondContact O-N 3.28Å; C450-C453 VanDerWaalsContact O-N 3.09Å; C453-I455 PolarHBondContact O-N 2.92Å; C453-S456 PolarHBondContact O-N 3.5Å; C453-E457 PolarHBondContact O-N 2.85Å
454	K	69.9	Low	78.9	Confident	137 Å²	137	98.6 Å²	98.6	60%	0.596	48%	0.481	S	S	*	.	H	α-helix	trans	-61.6	-42.5	175.4	-167	177.9	-179.5	-177.1	0	112.1	C450 Q451 T458	C450-K454 PolarHBondContact O-N 3.46Å; C450-K454 VanDerWaalsContact O-N 3.09Å; Q451-K454 PolarHBondContact O-N 2.96Å; K454-T458 WeakPolarHBondContact O-CB 3.46Å; K454-T458 PolarHBondContact O-N 2.92Å; K454-T458 PolarHBondContact O-OG1 3.44Å
455	I	75	Confident	78.3	Confident	94 Å²	94	99.5 Å²	99.5	48%	0.482	49%	0.487	S	S	.	.	H	α-helix	trans	-64.1	-45.7	174.4	-65.7	162.7	0	0	0	110.2	Q451 C453 E457 T458 N459	Q451-I455 WeakPolarHBondContact O-CG1 3.45Å; Q451-I455 PolarHBondContact O-N 3.25Å; C453-I455 PolarHBondContact O-N 2.92Å; I455-E457 PolarHBondContact O-N 3.38Å; I455-T458 PolarHBondContact O-N 3.29Å; I455-N459 WeakPolarHBondContact O-CB 3.07Å; I455-N459 VanDerWaalsContact O-CG 3.24Å; I455-N459 PolarHBondContact O-N 2.88Å; I455-N459 PolarHBondContact O-OD1 2.88Å
456	S	74.3	Confident	77.8	Confident	58 Å²	58	100.6 Å²	100.6	41%	0.406	50%	0.496	S	S	.	.	H	α-helix	trans	-60.6	-44.9	177.5	-175.3	0	0	0	0	112.8	K452 C453 T458 N459 Q460	K452-S456 PolarHBondContact O-N 3.01Å; K452-S456 VanDerWaalsContact O-N 3.07Å; C453-S456 PolarHBondContact O-N 3.5Å; S456-T458 VanDerWaalsContact C-N 3.33Å; S456-T458 PolarHBondContact O-N 3.12Å; S456-N459 PolarHBondContact O-N 3.18Å; S456-Q460 WeakPolarHBondContact O-CB 3.32Å; S456-Q460 WeakPolarHBondContact O-CG 3.3Å; S456-Q460 PolarHBondContact O-N 3.13Å
457	E	69.4	Low	77.2	Confident	67 Å²	67	102.1 Å²	102.1	31%	0.313	50%	0.499	S	S	.	.	H	α-helix	trans	-62.6	-39.6	174.6	-80.2	-173	179.8	0	0	112.1	C453 I455 Q460 R461	C453-E457 PolarHBondContact O-N 2.85Å; I455-E457 PolarHBondContact O-N 3.38Å; E457-Q460 PolarHBondContact O-N 2.86Å; E457-R461 WeakPolarHBondContact O-CG 3.44Å; E457-R461 PolarHBondContact O-N 3.11Å
458	T	77.3	Confident	76.5	Confident	71 Å²	71	109 Å²	109	44%	0.436	52%	0.521	S	S	.	.	H	α-helix	trans	-64.7	-47	177	-53	0	0	0	0	110.3	K454 I455 S456 Q460 R461 L462	K454-T458 WeakPolarHBondContact O-CB 3.46Å; K454-T458 PolarHBondContact O-N 2.92Å; K454-T458 PolarHBondContact O-OG1 3.44Å; I455-T458 PolarHBondContact O-N 3.29Å; S456-T458 VanDerWaalsContact C-N 3.33Å; S456-T458 PolarHBondContact O-N 3.12Å; T458-Q460 VanDerWaalsContact C-N 3.33Å; T458-Q460 PolarHBondContact O-N 2.82Å; T458-R461 PolarHBondContact O-N 3.38Å; T458-R461 VanDerWaalsContact O-N 3.17Å; T458-L462 HydrophobicContact CG2-CD1 4.21Å; T458-L462 WeakPolarHBondContact O-CG 3.29Å; T458-L462 PolarHBondContact O-N 3.02Å
459	N	80.8	Confident	76.2	Confident	85 Å²	85	109.2 Å²	109.2	46%	0.455	53%	0.532	S	S	.	.	H	α-helix	trans	-61.5	-40.3	176	-68.9	-8.6	0	0	0	111.8	I455 S456 L462 L463	I455-N459 WeakPolarHBondContact O-CB 3.07Å; I455-N459 VanDerWaalsContact O-CG 3.24Å; I455-N459 PolarHBondContact O-N 2.88Å; I455-N459 PolarHBondContact O-OD1 2.88Å; S456-N459 PolarHBondContact O-N 3.18Å; N459-L462 PolarHBondContact O-N 3.21Å; N459-L463 WeakPolarHBondContact O-CB 3.36Å; N459-L463 PolarHBondContact O-N 3.18Å
460	Q	78.5	Confident	75.9	Confident	108 Å²	108	108.4 Å²	108.4	51%	0.505	53%	0.528	S	S	.	.	H	α-helix	trans	-69.9	-28.4	176	-77.3	-173	-4.2	0	0	113.9	S456 E457 T458 R464	S456-Q460 WeakPolarHBondContact O-CB 3.32Å; S456-Q460 WeakPolarHBondContact O-CG 3.3Å; S456-Q460 PolarHBondContact O-N 3.13Å; E457-Q460 PolarHBondContact O-N 2.86Å; T458-Q460 VanDerWaalsContact C-N 3.33Å; T458-Q460 PolarHBondContact O-N 2.82Å; Q460-R464 WeakPolarHBondContact O-CG 3.32Å; Q460-R464 PolarHBondContact O-N 3.29Å; Q460-R464 PolarHBondContact O-NE 3.22Å
461	R	77.1	Confident	75.3	Confident	143 Å²	143	112.3 Å²	112.3	54%	0.54	54%	0.542	S	S	.	.	H	α-helix	trans	-72.5	-47.6	172	-78.2	-179.9	-173.9	-162.6	0.9	110.6	E457 T458 L463 R464 E465	E457-R461 WeakPolarHBondContact O-CG 3.44Å; E457-R461 PolarHBondContact O-N 3.11Å; T458-R461 PolarHBondContact O-N 3.38Å; T458-R461 VanDerWaalsContact O-N 3.17Å; R461-L463 VanDerWaalsContact C-N 3.3Å; R461-L463 PolarHBondContact O-N 3.05Å; R461-R464 WeakPolarHBondContact O-CB 3.15Å; R461-R464 PolarHBondContact O-N 3Å; R461-E465 WeakPolarHBondContact O-CG 3.14Å; R461-E465 PolarHBondContact O-N 3.26Å
462	L	81.3	Confident	74.7	Confident	87 Å²	87	109.9 Å²	109.9	46%	0.455	54%	0.54	S	S	.	.	H	α-helix	trans	-56.2	-45.2	174	-70.6	169.3	0	0	0	110.9	T458 N459 R464 E465 T466	T458-L462 HydrophobicContact CG2-CD1 4.21Å; T458-L462 WeakPolarHBondContact O-CG 3.29Å; T458-L462 PolarHBondContact O-N 3.02Å; N459-L462 PolarHBondContact O-N 3.21Å; L462-R464 VanDerWaalsContact C-N 3.3Å; L462-R464 PolarHBondContact O-N 3.21Å; L462-E465 PolarHBondContact O-N 3.33Å; L462-T466 WeakPolarHBondContact O-CG2 3.35Å; L462-T466 PolarHBondContact O-N 3.27Å; L462-T466 PolarHBondContact O-OG1 2.64Å; L462-T466 VanDerWaalsContact O-OG1 3.05Å
463	L	79.6	Confident	74	Confident	111 Å²	111	107.3 Å²	107.3	58%	0.581	54%	0.541	S	S	*	.	H	α-helix	trans	-60.3	-38.1	176.4	-122.6	97.4	0	0	0	112.8	N459 R461 T466 N467	N459-L463 WeakPolarHBondContact O-CB 3.36Å; N459-L463 PolarHBondContact O-N 3.18Å; R461-L463 VanDerWaalsContact C-N 3.3Å; R461-L463 PolarHBondContact O-N 3.05Å; L463-T466 VanDerWaalsContact C-OG1 3.31Å; L463-T466 VanDerWaalsContact CA-OG1 3.28Å; L463-T466 WeakPolarHBondContact CA-OG1 3.29Å; L463-T466 PolarHBondContact O-OG1 3.44Å; L463-N467 WeakPolarHBondContact O-CB 3.45Å; L463-N467 PolarHBondContact O-N 2.99Å; L463-N467 PolarHBondContact O-ND2 2.02Å; L463-N467 PolarHBondContact O-OD1 3.18Å
464	R	77.7	Confident	73.5	Confident	165 Å²	165	109.6 Å²	109.6	62%	0.623	56%	0.557	S	S	*	*	H	α-helix	trans	-70.7	-41	177.4	-85.5	-175.1	-90.1	-178.3	-12.8	111.9	Q460 R461 L462 N467 Y468	Q460-R464 WeakPolarHBondContact O-CG 3.32Å; Q460-R464 PolarHBondContact O-N 3.29Å; Q460-R464 PolarHBondContact O-NE 3.22Å; R461-R464 WeakPolarHBondContact O-CB 3.15Å; R461-R464 PolarHBondContact O-N 3Å; L462-R464 VanDerWaalsContact C-N 3.3Å; L462-R464 PolarHBondContact O-N 3.21Å; R464-N467 PolarHBondContact O-N 3.18Å; R464-Y468 WeakPolarHBondContact O-CB 3.21Å; R464-Y468 PolarHBondContact O-N 3Å
465	E	78.9	Confident	72.6	Confident	113 Å²	113	110.7 Å²	110.7	53%	0.528	57%	0.569	S	S	.	*	H	α-helix	trans	-64.8	-43.1	175.6	-72.4	169.9	-177.2	0	0	111	R461 L462 N467 Y468 L469	R461-E465 WeakPolarHBondContact O-CG 3.14Å; R461-E465 PolarHBondContact O-N 3.26Å; L462-E465 PolarHBondContact O-N 3.33Å; E465-N467 PolarHBondContact O-N 3.11Å; E465-Y468 PolarHBondContact O-N 3.39Å; E465-L469 WeakPolarHBondContact O-CG 3.41Å; E465-L469 PolarHBondContact O-N 2.89Å
466	T	78.9	Confident	71.4	Confident	66 Å²	66	114.9 Å²	114.9	41%	0.405	58%	0.584	S	S	.	*	H	α-helix	trans	-64.4	-39.5	174.2	51.8	0	0	0	0	112.2	L462 L463 Y468 L469 N470	L462-T466 WeakPolarHBondContact O-CG2 3.35Å; L462-T466 PolarHBondContact O-N 3.27Å; L462-T466 PolarHBondContact O-OG1 2.64Å; L462-T466 VanDerWaalsContact O-OG1 3.05Å; L463-T466 VanDerWaalsContact C-OG1 3.31Å; L463-T466 VanDerWaalsContact CA-OG1 3.28Å; L463-T466 WeakPolarHBondContact CA-OG1 3.29Å; L463-T466 PolarHBondContact O-OG1 3.44Å; T466-Y468 VanDerWaalsContact C-N 3.33Å; T466-Y468 PolarHBondContact O-N 2.85Å; T466-L469 PolarHBondContact O-N 2.98Å; T466-N470 WeakPolarHBondContact O-CB 3.41Å; T466-N470 PolarHBondContact O-N 3.01Å; T466-N470 PolarHBondContact O-ND2 2.89Å
467	N	77.4	Confident	70.2	Confident	99 Å²	99	117.8 Å²	117.8	53%	0.529	60%	0.602	S	S	.	*	H	α-helix	trans	-67.2	-35	177.2	-73.4	-8.5	0	0	0	112.2	L463 R464 E465 N470 E471	L463-N467 WeakPolarHBondContact O-CB 3.45Å; L463-N467 PolarHBondContact O-N 2.99Å; L463-N467 PolarHBondContact O-ND2 2.02Å; L463-N467 PolarHBondContact O-OD1 3.18Å; R464-N467 PolarHBondContact O-N 3.18Å; E465-N467 PolarHBondContact O-N 3.11Å; N467-N470 PolarHBondContact O-N 3.48Å; N467-E471 PolarHBondContact O-N 3.24Å
468	Y	71.9	Confident	69.4	Low	181 Å²	181	127.8 Å²	127.8	71%	0.71	64%	0.644	S	S	*	*	H	α-helix	trans	-70.1	-37.8	175.8	-161.6	-95.7	0	0	0	112	R464 E465 T466 N470 E471	R464-Y468 WeakPolarHBondContact O-CB 3.21Å; R464-Y468 PolarHBondContact O-N 3Å; E465-Y468 PolarHBondContact O-N 3.39Å; T466-Y468 VanDerWaalsContact C-N 3.33Å; T466-Y468 PolarHBondContact O-N 2.85Å; Y468-N470 VanDerWaalsContact C-N 3.33Å; Y468-E471 PolarHBondContact O-N 2.75Å
469	L	73.7	Confident	69	Low	143 Å²	143	130.7 Å²	130.7	75%	0.749	66%	0.655	S	S	*	*	H	α-helix	trans	-70.6	-28.5	174.9	-71.1	168.8	0	0	0	113.1	E465 T466 E471	E465-L469 WeakPolarHBondContact O-CG 3.41Å; E465-L469 PolarHBondContact O-N 2.89Å; T466-L469 PolarHBondContact O-N 2.98Å; L469-E471 VanDerWaalsContact C-N 3.34Å
470	N	74.5	Confident	68.4	Low	125 Å²	125	133.1 Å²	133.1	67%	0.668	67%	0.665	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.4	-2.7	177.9	-68.8	-17.2	0	0	0	113.2	T466 N467 Y468 P472	T466-N470 WeakPolarHBondContact O-CB 3.41Å; T466-N470 PolarHBondContact O-N 3.01Å; T466-N470 PolarHBondContact O-ND2 2.89Å; N467-N470 PolarHBondContact O-N 3.48Å; Y468-N470 VanDerWaalsContact C-N 3.33Å; N470-P472 WeakPolarHBondContact O-CD 3.41Å
471	E	64.5	Low	67.8	Low	133 Å²	133	134.4 Å²	134.4	62%	0.621	67%	0.674	S	S	*	*	S	Bend	trans	-70.5	117	175	-142.3	170.5	-167.5	0	0	107.7	N467 Y468 L469	N467-E471 PolarHBondContact O-N 3.24Å; Y468-E471 PolarHBondContact O-N 2.75Å; L469-E471 VanDerWaalsContact C-N 3.34Å
472	P	62.6	Low	67.3	Low	105 Å²	105	133.9 Å²	133.9	68%	0.682	68%	0.682	S	S	*	*	P	Polyproline II helix	trans	-60.3	142.1	-178.4	23.7	-31.7	0	0	0	109.3	N470 S474	N470-P472 WeakPolarHBondContact O-CD 3.41Å; P472-S474 PolarHBondContact O-N 3.42Å
473	P	59.1	Low	66.4	Low	120 Å²	120	136.9 Å²	136.9	78%	0.779	70%	0.696	S	S	*	*	P	Polyproline II helix	trans	-54.5	119.9	179.5	20.9	-30.3	0	0	0	108.3	N475	P473-N475 PolarHBondContact O-N 2.99Å
474	S	61.3	Low	65.5	Low	90 Å²	90	138.6 Å²	138.6	63%	0.629	70%	0.704	S	S	*	*	P	Polyproline II helix	trans	-54.2	118.9	174.7	46.9	0	0	0	0	107.4	P472 F476	P472-S474 PolarHBondContact O-N 3.42Å; S474-F476 VanDerWaalsContact C-N 3.3Å; S474-F476 PolarHBondContact O-N 3.12Å
475	N	51.2	Low	64.7	Low	160 Å²	160	136.7 Å²	136.7	86%	0.856	71%	0.71	S	S	*	*			trans	-54.4	101.5	169.3	-81.9	-24.5	0	0	0	106.8	P473 P477	P473-N475 PolarHBondContact O-N 2.99Å; N475-P477 WeakPolarHBondContact O-CD 3.41Å
476	F	48.8	Very low	63.6	Low	183 Å²	183	138.5 Å²	138.5	80%	0.803	72%	0.724	S	S	*	*			trans	-64.6	113.6	167.3	-93.2	-88.2	0	0	0	106.5	S474 K478	S474-F476 VanDerWaalsContact C-N 3.3Å; S474-F476 PolarHBondContact O-N 3.12Å; F476-K478 PolarHBondContact O-N 3.08Å
477	P	50.6	Low	62.3	Low	118 Å²	118	144.6 Å²	144.6	77%	0.766	75%	0.75	S	S	*	*			trans	-71.7	120.6	164.2	26.5	-18.1	0	0	0	106.5	N475	N475-P477 WeakPolarHBondContact O-CD 3.41Å
478	K	52.1	Low	60.9	Low	278 Å²	278	148.7 Å²	148.7	100%	1.209	77%	0.77	S	S	*	*			trans	-75.8	0	157.3	-88.2	-173	176.2	179.9	0	109.4	F476	F476-K478 PolarHBondContact O-N 3.08Å

Retrieved 478 of 478 residues in 99.7 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).