G4VEH5_SCHMA Loading...

Putative cyclin G

AlphaFold DB , UniProt , Accession G4VEH5, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 502 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	34.9	Very low	29	Very low	250 Å²	250	153.4 Å²	153.4	100%	1.232	80%	0.797	S	S	*	*				0	109.4	0	-82.1	-172	176.1	0	0	108.8
2	A	36.3	Very low	29.1	Very low	95 Å²	95	158.3 Å²	158.3	79%	0.785	81%	0.808	S	S	*	*			trans	163.8	78	162.1	0	0	0	0	0	105.6
3	K	32.5	Very low	28.4	Very low	198 Å²	198	154.3 Å²	154.3	86%	0.861	80%	0.803	S	S	*	*				40	96.7	93.1	-84.9	-176.5	175.5	178.4	0	111.8
4	V	29.1	Very low	28.6	Very low	117 Å²	117	151.1 Å²	151.1	71%	0.709	80%	0.8	S	S	*	*				70.8	118.7	84.7	171.7	0	0	0	0	111.7
5	L	35.6	Very low	28.3	Very low	160 Å²	160	152.9 Å²	152.9	84%	0.838	80%	0.802	S	S	*	*			trans	166.6	147.6	132.8	-106.5	114.4	0	0	0	107.7
6	N	27.2	Very low	28	Very low	106 Å²	106	150.7 Å²	150.7	57%	0.567	80%	0.798	S	S	*	*			cis	179.1	151.7	-29.1	-132.2	-16	0	0	0	104.7
7	Q	27.7	Very low	28	Very low	154 Å²	154	149.6 Å²	149.6	72%	0.72	80%	0.798	S	S	*	*			trans	65.6	115.6	142.9	-70.5	167	-3.5	0	0	119.1
8	H	25.8	Very low	27.8	Very low	181 Å²	181	152 Å²	152	84%	0.838	80%	0.804	S	S	*	*				81.2	143.7	74.7	-97.6	56.1	0	0	0	115
9	Q	25.8	Very low	28	Very low	171 Å²	171	150.5 Å²	150.5	80%	0.799	81%	0.807	S	S	*	*			trans	86.9	145.1	168.2	-65.9	179.5	-4	0	0	117.4
10	Q	22.9	Very low	27.9	Very low	158 Å²	158	150.7 Å²	150.7	74%	0.738	81%	0.808	S	S	*	*			cis	-175.7	145.3	-27.7	-122.8	177.3	-6.2	0	0	105
11	S	21.3	Very low	28	Very low	97 Å²	97	150.9 Å²	150.9	68%	0.678	81%	0.808	S	S	*	*			trans	26.4	119.8	151.4	55.9	0	0	0	0	121.1
12	F	30.2	Very low	27.5	Very low	212 Å²	212	147.5 Å²	147.5	93%	0.93	80%	0.795	S	S	*	*			trans	-125.3	127.7	138.7	-97.4	-84.3	0	0	0	110.2
13	S	20.1	Very low	27.1	Very low	107 Å²	107	145.7 Å²	145.7	75%	0.748	79%	0.786	S	S	*	*			trans	-107.5	130.2	173.2	53.7	0	0	0	0	109.5
14	S	30.9	Very low	26.9	Very low	109 Å²	109	142.6 Å²	142.6	76%	0.762	79%	0.788	S	S	*	*			trans	-166.8	102.9	156.4	26.5	0	0	0	0	112.6
15	Q	23.7	Very low	26.8	Very low	178 Å²	178	143.3 Å²	143.3	83%	0.832	79%	0.792	S	S	*	*				52.9	117.4	126.4	-68	-179.4	10	0	0	122.3
16	T	24.1	Very low	26.5	Very low	118 Å²	118	139.5 Å²	139.5	72%	0.724	78%	0.784	S	S	*	*				50.7	120.5	130	60.6	0	0	0	0	118.8
17	T	28.4	Very low	26.5	Very low	132 Å²	132	138.6 Å²	138.6	81%	0.81	79%	0.786	S	S	*	*				-175.6	157	69.8	36.9	0	0	0	0	110.5
18	H	24	Very low	26.5	Very low	193 Å²	193	140.3 Å²	140.3	89%	0.894	79%	0.791	S	S	*	*			trans	-53.2	134.5	179.1	-64.7	-87.7	0	0	0	115.8
19	S	32.3	Very low	26.7	Very low	124 Å²	124	141.8 Å²	141.8	87%	0.867	79%	0.791	S	S	*	*			trans	-161.2	149.7	133.9	58.8	0	0	0	0	111.6
20	N	25.7	Very low	27	Very low	154 Å²	154	139 Å²	139	82%	0.824	79%	0.786	S	S	*	*			trans	-74.6	163.4	-160.3	-81.2	-28.4	0	0	0	116.2
21	N	29.7	Very low	27.5	Very low	154 Å²	154	136 Å²	136	82%	0.824	79%	0.788	S	S	*	*			trans	84.3	82.2	155.9	-70.1	-4.1	0	0	0	118	G23	N21-G23 PolarHBondContact O-N 3.15Å
22	N	25.2	Very low	27.9	Very low	179 Å²	179	140.1 Å²	140.1	96%	0.957	79%	0.794	S	S	*	*			trans	-52.5	94.6	143.4	-72.4	-19.4	0	0	0	110.4
23	G	28.1	Very low	27.8	Very low	57 Å²	57	134 Å²	134	59%	0.588	78%	0.777	S	S	*	*			trans	-122.3	107.2	161.7	0	0	0	0	0	107.4	N21 V25	N21-G23 PolarHBondContact O-N 3.15Å; G23-V25 PolarHBondContact O-N 3.26Å
24	C	27.9	Very low	28.5	Very low	133 Å²	133	140.5 Å²	140.5	90%	0.899	79%	0.785	S	S	*	*			trans	-44.5	112.9	177.7	-68.8	0	0	0	0	110.7	A26	C24-A26 PolarHBondContact O-N 3.43Å
25	V	26.6	Very low	28.5	Very low	133 Å²	133	142.3 Å²	142.3	81%	0.806	78%	0.779	S	S	*	*			trans	-68.4	87.4	169.7	-179.8	0	0	0	0	106.6	G23 S27	G23-V25 PolarHBondContact O-N 3.26Å; V25-S27 PolarHBondContact O-N 3.39Å
26	A	28.2	Very low	28.6	Very low	79 Å²	79	141.7 Å²	141.7	65%	0.653	78%	0.782	S	S	*	*			trans	-62	103.7	164	0	0	0	0	0	106.2	C24 F28	C24-A26 PolarHBondContact O-N 3.43Å; A26-F28 PolarHBondContact O-N 2.96Å
27	S	27.5	Very low	29.1	Very low	87 Å²	87	144.2 Å²	144.2	61%	0.608	78%	0.783	S	S	*	*			trans	-53.8	115	175	-69.4	0	0	0	0	108.7	V25 Y29	V25-S27 PolarHBondContact O-N 3.39Å; S27-Y29 PolarHBondContact O-N 3.28Å
28	F	28.4	Very low	29.2	Very low	191 Å²	191	145.3 Å²	145.3	84%	0.838	78%	0.783	S	S	*	*			trans	-61.6	84.9	164.4	-69.4	-87.7	0	0	0	108.2	A26 T30	A26-F28 PolarHBondContact O-N 2.96Å; F28-T30 PolarHBondContact O-N 3.49Å
29	Y	30.8	Very low	29.6	Very low	211 Å²	211	144.2 Å²	144.2	83%	0.827	77%	0.771	S	S	*	*			trans	-66.7	81.7	151.8	-76.9	-81.1	0	0	0	106.4	S27 A31	S27-Y29 PolarHBondContact O-N 3.28Å; Y29-A31 PolarHBondContact O-N 3.49Å
30	T	31	Very low	29.5	Very low	113 Å²	113	141 Å²	141	69%	0.693	75%	0.752	S	S	*	*			trans	-58.6	97.4	148.3	48.1	0	0	0	0	104.7	F28 K32	F28-T30 PolarHBondContact O-N 3.49Å; T30-K32 PolarHBondContact O-N 3.03Å
31	A	34.5	Very low	29.7	Very low	94 Å²	94	138.1 Å²	138.1	78%	0.777	74%	0.742	S	S	*	*			trans	-68.7	73.3	176.8	0	0	0	0	0	108.4	Y29 S33	Y29-A31 PolarHBondContact O-N 3.49Å; A31-S33 PolarHBondContact O-N 3.46Å
32	K	28.4	Very low	29.7	Very low	185 Å²	185	139.2 Å²	139.2	80%	0.804	74%	0.739	S	S	*	*			trans	-62.8	99.7	151.3	-79	-179.9	176	175.9	0	104.9	T30 R34	T30-K32 PolarHBondContact O-N 3.03Å; K32-R34 PolarHBondContact O-N 3.25Å
33	S	29	Very low	30.1	Very low	82 Å²	82	139 Å²	139	57%	0.573	73%	0.725	S	S	*	*			trans	-40.9	112.2	177.1	179.1	0	0	0	0	110	A31 F35	A31-S33 PolarHBondContact O-N 3.46Å; S33-F35 PolarHBondContact O-N 2.99Å; S33-F35 VanDerWaalsContact O-N 3.17Å; S33-F35 PolarHBondContact OG-O 3.26Å
34	R	35.1	Very low	30.3	Very low	245 Å²	245	140.9 Å²	140.9	93%	0.925	73%	0.725	S	S	*	*	S	Bend	trans	-71.8	0.6	178.1	-86.9	-170.3	177.1	-178.3	0	113.5	K32	K32-R34 PolarHBondContact O-N 3.25Å
35	F	30.2	Very low	30.7	Very low	147 Å²	147	139.1 Å²	139.1	65%	0.645	71%	0.706	S	S	*	*	S	Bend	trans	-122.6	115	165	-79.9	-89.7	0	0	0	108.1	S33 F37	S33-F35 PolarHBondContact O-N 2.99Å; S33-F35 VanDerWaalsContact O-N 3.17Å; S33-F35 PolarHBondContact OG-O 3.26Å; F35-F37 HydrophobicContact CB-CD2 3.67Å; F35-F37 HydrophobicContact CB-CE2 3.49Å; F35-F37 VanDerWaalsContact CB-CE2 3.49Å; F35-F37 HydrophobicContact CB-CG 4.45Å; F35-F37 HydrophobicContact CB-CZ 4.14Å; F35-F37 HydrophobicContact CG-CE2 4.19Å; F35-F37 HydrophobicContact CG-CZ 4.49Å; F35-F37 PolarHBondContact O-N 3.47Å
36	N	26.7	Very low	30.9	Very low	164 Å²	164	136.7 Å²	136.7	88%	0.877	69%	0.694	S	S	*	*			trans	-60.1	72.8	158.1	-75.7	-27.5	0	0	0	107.9	L38	N36-L38 VanDerWaalsContact C-N 3.29Å; N36-L38 PolarHBondContact O-N 3.45Å
37	F	34.5	Very low	31	Very low	171 Å²	171	141.7 Å²	141.7	75%	0.75	70%	0.704	S	S	*	*			trans	-66.3	104	161.3	-76.8	-69.6	0	0	0	105	F35 R39	F35-F37 HydrophobicContact CB-CD2 3.67Å; F35-F37 HydrophobicContact CB-CE2 3.49Å; F35-F37 VanDerWaalsContact CB-CE2 3.49Å; F35-F37 HydrophobicContact CB-CG 4.45Å; F35-F37 HydrophobicContact CB-CZ 4.14Å; F35-F37 HydrophobicContact CG-CE2 4.19Å; F35-F37 HydrophobicContact CG-CZ 4.49Å; F35-F37 PolarHBondContact O-N 3.47Å; F37-R39 PolarHBondContact O-N 3.44Å
38	L	30.5	Very low	31.2	Very low	156 Å²	156	147.1 Å²	147.1	82%	0.817	71%	0.713	S	S	*	*			trans	-36.2	107.7	164	-68.6	165.1	0	0	0	107.2	N36 A40	N36-L38 VanDerWaalsContact C-N 3.29Å; N36-L38 PolarHBondContact O-N 3.45Å; L38-A40 PolarHBondContact O-N 2.91Å
39	R	31.8	Very low	31.2	Very low	169 Å²	169	148.7 Å²	148.7	64%	0.638	71%	0.713	S	S	*	*			trans	-43	114.6	169.4	-176.1	177.5	-169.9	164.2	7.9	105.5	F37 P41 E436	F37-R39 PolarHBondContact O-N 3.44Å; R39-P41 VanDerWaalsContact O-CD 3.31Å; R39-P41 WeakPolarHBondContact O-CD 3.47Å; R39-E436 IonicContact NH2-OE1 3.92Å; R39-E436 PolarHBondContact NH2-OE1 3.2Å; R39-E436 IonicContact NH2-OE2 2.78Å
40	A	29.2	Very low	31.8	Very low	57 Å²	57	144.7 Å²	144.7	47%	0.471	70%	0.697	S	S	.	*			trans	-51.2	118.1	175.7	0	0	0	0	0	105.9	L38 K42	L38-A40 PolarHBondContact O-N 2.91Å; A40-K42 PolarHBondContact O-N 3.46Å
41	P	29.6	Very low	31.9	Very low	94 Å²	94	148.4 Å²	148.4	61%	0.61	70%	0.699	S	S	*	*			trans	-58	140.1	-173	17.6	-27.8	0	0	0	108.1	R39 R43	R39-P41 VanDerWaalsContact O-CD 3.31Å; R39-P41 WeakPolarHBondContact O-CD 3.47Å; P41-R43 VanDerWaalsContact C-N 3.26Å; P41-R43 PolarHBondContact O-N 2.89Å
42	K	30.2	Very low	31.8	Very low	176 Å²	176	149.9 Å²	149.9	77%	0.765	70%	0.701	S	S	*	*			trans	-53.1	91	174.5	-71.8	-179	176.9	-179.4	0	108.6	A40 T44	A40-K42 PolarHBondContact O-N 3.46Å; K42-T44 PolarHBondContact O-N 3.32Å
43	R	33.9	Very low	32	Very low	176 Å²	176	146.7 Å²	146.7	66%	0.664	70%	0.702	S	S	*	*			trans	-82.3	113.4	167.6	-73.1	-175.5	176.8	148.3	-1.7	105.1	P41 I45	P41-R43 VanDerWaalsContact C-N 3.26Å; P41-R43 PolarHBondContact O-N 2.89Å; R43-I45 PolarHBondContact O-N 3.28Å
44	T	31.6	Very low	32.1	Very low	95 Å²	95	153.5 Å²	153.5	58%	0.583	72%	0.715	S	S	*	*			trans	-52.6	126.3	165.4	24.7	0	0	0	0	108.1	K42 S46 L135	K42-T44 PolarHBondContact O-N 3.32Å; T44-S46 PolarHBondContact O-N 3.32Å; T44-L135 HydrophobicContact CG2-CB 4.26Å; T44-L135 HydrophobicContact CG2-CD1 3.73Å
45	I	36.1	Very low	32	Very low	97 Å²	97	149.5 Å²	149.5	50%	0.497	71%	0.71	S	S	.	*			trans	-51.3	98.4	176.6	-62.5	167.3	0	0	0	108.4	R43 Q47 L447	R43-I45 PolarHBondContact O-N 3.28Å; I45-Q47 HydrophobicContact CG2-CG 4.4Å; I45-L447 HydrophobicContact CD1-CD1 4.26Å
46	S	31.7	Very low	32	Very low	81 Å²	81	153.5 Å²	153.5	57%	0.566	72%	0.721	S	S	*	*			trans	-85.8	112.1	167.2	50.8	0	0	0	0	107.1	T44 Y48	T44-S46 PolarHBondContact O-N 3.32Å; S46-Y48 VanDerWaalsContact C-N 3.34Å; S46-Y48 PolarHBondContact O-N 3.23Å
47	Q	30.9	Very low	32.2	Very low	184 Å²	184	157 Å²	157	86%	0.86	72%	0.722	S	S	*	*			trans	-71.2	91.7	171.5	-66	-155.5	-6.5	0	0	109.3	I45 R49	I45-Q47 HydrophobicContact CG2-CG 4.4Å; Q47-R49 PolarHBondContact O-N 2.83Å; Q47-R49 VanDerWaalsContact O-N 3.13Å
48	Y	31.4	Very low	32.1	Very low	202 Å²	202	153.1 Å²	153.1	79%	0.792	72%	0.721	S	S	*	*			trans	-73.7	97.2	161.6	-79.5	-83.8	0	0	0	108.2	S46 R50	S46-Y48 VanDerWaalsContact C-N 3.34Å; S46-Y48 PolarHBondContact O-N 3.23Å; Y48-R50 PolarHBondContact O-N 3.35Å
49	R	28.1	Very low	32.3	Very low	224 Å²	224	154.1 Å²	154.1	85%	0.845	72%	0.722	S	S	*	*			trans	-66.3	104.1	168.8	-147.9	-178.3	-162.8	-168.4	5.2	107.6	Q47 Y51	Q47-R49 PolarHBondContact O-N 2.83Å; Q47-R49 VanDerWaalsContact O-N 3.13Å; R49-Y51 PolarHBondContact O-N 3.01Å
50	R	43.9	Very low	32.1	Very low	126 Å²	126	155.9 Å²	155.9	48%	0.475	73%	0.734	S	S	.	*			trans	-64.3	125.6	178.8	-72.1	-175.7	-175	171.3	3.2	110	Y48 D197	Y48-R50 PolarHBondContact O-N 3.35Å; R50-D197 IonicContact CZ-OD1 2.7Å; R50-D197 IonicContact NH2-OD1 3.44Å; R50-D197 PolarHBondContact NH2-OD1 2.76Å; R50-D197 IonicContact NH2-OD2 2.75Å; R50-D197 PolarHBondContact NH2-OD2 3.43Å
51	Y	32.7	Very low	32	Very low	192 Å²	192	163.4 Å²	163.4	75%	0.753	75%	0.752	S	S	*	*			trans	-91.4	143.8	159.8	-78.5	-87.2	0	0	0	108.6	R49 S53	R49-Y51 PolarHBondContact O-N 3.01Å; Y51-S53 PolarHBondContact O-N 2.91Å
52	P	31.4	Very low	31.7	Very low	124 Å²	124	166.7 Å²	166.7	81%	0.805	76%	0.759	S	S	*	*			trans	-63.9	105.7	179	24	-31.3	0	0	0	110.3	R54	P52-R54 VanDerWaalsContact C-N 3.34Å; P52-R54 PolarHBondContact O-N 2.91Å
53	S	33.8	Very low	31.7	Very low	119 Å²	119	164.2 Å²	164.2	83%	0.832	76%	0.761	S	S	*	*			trans	-73.2	85.3	173.1	29.7	0	0	0	0	109.6	Y51	Y51-S53 PolarHBondContact O-N 2.91Å
54	R	30.4	Very low	31.3	Very low	224 Å²	224	162.7 Å²	162.7	85%	0.845	77%	0.766	S	S	*	*			trans	-111	74.2	163.4	-152.4	-172.1	-77.5	178.4	-4.4	109	P52 R56	P52-R54 VanDerWaalsContact C-N 3.34Å; P52-R54 PolarHBondContact O-N 2.91Å; R54-R56 PolarHBondContact O-N 3.48Å
55	I	33.1	Very low	31.4	Very low	161 Å²	161	163.4 Å²	163.4	83%	0.826	77%	0.772	S	S	*	*			trans	-75	109.5	163.4	-74.6	169.2	0	0	0	106.5	R57	I55-R57 PolarHBondContact O-N 3.37Å
56	R	30.2	Very low	31.1	Very low	232 Å²	232	165.7 Å²	165.7	88%	0.875	79%	0.79	S	S	*	*			trans	-56.9	109	170.2	-88.5	179.5	173.1	161.6	-2.8	108.1	R54 A58	R54-R56 PolarHBondContact O-N 3.48Å; R56-A58 PolarHBondContact O-N 3.16Å
57	R	30.3	Very low	30.7	Very low	237 Å²	237	167 Å²	167	89%	0.894	80%	0.799	S	S	*	*			trans	-64.9	103.1	161.2	-169.8	178.2	-91	-176.7	-5.6	106.1	I55 Q59	I55-R57 PolarHBondContact O-N 3.37Å; R57-Q59 PolarHBondContact O-N 2.9Å
58	A	33.8	Very low	30.5	Very low	89 Å²	89	164.1 Å²	164.1	74%	0.736	80%	0.8	S	S	*	*			trans	-55.2	131.7	177.3	0	0	0	0	0	109.2	R56 K60	R56-A58 PolarHBondContact O-N 3.16Å; A58-K60 PolarHBondContact O-N 2.91Å
59	Q	33.4	Very low	30.2	Very low	178 Å²	178	158 Å²	158	83%	0.832	80%	0.798	S	S	*	*			trans	-57.5	126.2	-178.6	-70.8	166.2	-55.7	0	0	109.6	R57 Y61	R57-Q59 PolarHBondContact O-N 2.9Å; Q59-Y61 PolarHBondContact O-N 3.22Å
60	K	28.5	Very low	29.9	Very low	205 Å²	205	154.5 Å²	154.5	89%	0.891	80%	0.796	S	S	*	*			trans	-54.3	110.2	159.7	-89.2	-179.6	170.2	-176.4	0	107.2	A58 E62	A58-K60 PolarHBondContact O-N 2.91Å; K60-E62 PolarHBondContact O-N 3.36Å
61	Y	27.8	Very low	29.1	Very low	216 Å²	216	155.7 Å²	155.7	85%	0.847	81%	0.812	S	S	*	*			trans	-73.1	109.5	160.8	-105	-96.9	0	0	0	107.1	Q59	Q59-Y61 PolarHBondContact O-N 3.22Å
62	E	23.6	Very low	28.8	Very low	163 Å²	163	151 Å²	151	76%	0.762	81%	0.807	S	S	*	*			trans	-84	122.5	154.8	-87.8	-156.5	159.5	0	0	108.3	K60	K60-E62 PolarHBondContact O-N 3.36Å
63	P	28.6	Very low	28.5	Very low	123 Å²	123	152.4 Å²	152.4	80%	0.799	80%	0.803	S	S	*	*			trans	-89.5	111.3	167.1	25.3	-13.8	0	0	0	109.4
64	N	26.2	Very low	28.1	Very low	144 Å²	144	155.3 Å²	155.3	77%	0.77	80%	0.801	S	S	*	*			trans	-93.8	153.1	166	-97.6	-24.2	0	0	0	111.3
65	P	34.3	Very low	27.8	Very low	110 Å²	110	149.7 Å²	149.7	71%	0.714	80%	0.796	S	S	*	*			trans	-104.1	149.1	-152	37.2	-29.9	0	0	0	113.4
66	V	29.6	Very low	27.2	Very low	145 Å²	145	149.5 Å²	149.5	88%	0.879	80%	0.796	S	S	*	*			trans	-135.9	104.5	157.6	-169.5	0	0	0	0	109.9
67	S	23.9	Very low	27	Very low	108 Å²	108	146 Å²	146	76%	0.755	79%	0.794	S	S	*	*			trans	5.4	128.2	140.5	-171.1	0	0	0	0	119.1
68	S	25.1	Very low	26.6	Very low	124 Å²	124	141.3 Å²	141.3	87%	0.867	79%	0.785	S	S	*	*				136.7	125.5	117.2	-165.6	0	0	0	0	112.3
69	G	25.4	Very low	26.2	Very low	73 Å²	73	144.7 Å²	144.7	75%	0.753	79%	0.791	S	S	*	*			trans	146.3	90.1	163.5	0	0	0	0	0	114.3
70	N	22.8	Very low	25.6	Very low	152 Å²	152	142.8 Å²	142.8	81%	0.813	79%	0.785	S	S	*	*			trans	-54.1	143.1	168.8	-57.4	-34.8	0	0	0	112
71	D	26.5	Very low	25.4	Very low	151 Å²	151	140.2 Å²	140.2	81%	0.807	78%	0.78	S	S	*	*				179.5	134.4	100	-93	-28.4	0	0	0	113.4
72	S	25.7	Very low	25.1	Very low	93 Å²	93	135.9 Å²	135.9	65%	0.65	78%	0.78	S	S	*	*			trans	-8.5	132.5	158.3	65.3	0	0	0	0	120.5
73	Q	26.8	Very low	25	Very low	153 Å²	153	131.6 Å²	131.6	72%	0.715	78%	0.779	S	S	*	*				156.5	127	100.9	-81.6	-162.9	-1.2	0	0	111.7
74	K	23.6	Very low	24.8	Very low	180 Å²	180	130.5 Å²	130.5	78%	0.783	78%	0.78	S	S	*	*			trans	56.2	139.5	139.9	-63.2	174	178.8	174.5	0	118.2
75	S	25.4	Very low	24.6	Very low	107 Å²	107	127.7 Å²	127.7	75%	0.748	78%	0.777	S	S	*	*			cis	-171.7	141.8	4.4	36.8	0	0	0	0	106.4
76	N	20.9	Very low	24.1	Very low	156 Å²	156	129.4 Å²	129.4	83%	0.834	78%	0.78	S	S	*	*			trans	-52.1	142.3	164.8	-65.1	-32	0	0	0	111.5
77	I	25.9	Very low	23.9	Very low	160 Å²	160	127.1 Å²	127.1	82%	0.821	77%	0.771	S	S	*	*			trans	-159.8	125.7	132.2	-91.3	143.8	0	0	0	107.4
78	I	21.7	Very low	24	Very low	137 Å²	137	131.2 Å²	131.2	70%	0.703	78%	0.775	S	S	*	*			trans	-81.9	136.1	169.3	-68.1	160	0	0	0	106.2	I80	I78-I80 HydrophobicContact CG2-CD1 4.45Å; I78-I80 HydrophobicContact CG2-CG1 4.38Å
79	D	25.4	Very low	24	Very low	161 Å²	161	134.7 Å²	134.7	86%	0.861	78%	0.778	S	S	*	*			trans	-150.8	138.5	144.1	-97.6	-31.2	0	0	0	112.1
80	I	21.1	Very low	23.9	Very low	138 Å²	138	137.2 Å²	137.2	71%	0.708	78%	0.779	S	S	*	*			trans	-109.5	153.9	-173.7	-70	169	0	0	0	107.2	I78	I78-I80 HydrophobicContact CG2-CD1 4.45Å; I78-I80 HydrophobicContact CG2-CG1 4.38Å
81	L	22.7	Very low	23.9	Very low	151 Å²	151	134 Å²	134	79%	0.791	77%	0.773	S	S	*	*			trans	108.4	114.2	148.8	-131.4	77.8	0	0	0	118.7
82	C	21.1	Very low	23.8	Very low	125 Å²	125	135.2 Å²	135.2	85%	0.845	77%	0.774	S	S	*	*			trans	42.7	132.1	137.3	-73.3	0	0	0	0	122.2
83	G	21.9	Very low	23.6	Very low	72 Å²	72	139.5 Å²	139.5	74%	0.742	78%	0.78	S	S	*	*			trans	162.5	103.4	141.2	0	0	0	0	0	116.3
84	A	24.5	Very low	23.7	Very low	100 Å²	100	140.2 Å²	140.2	83%	0.826	79%	0.787	S	S	*	*			trans	66.4	118.1	141.2	0	0	0	0	0	121.3
85	A	22.4	Very low	23.5	Very low	85 Å²	85	139.4 Å²	139.4	70%	0.702	78%	0.784	S	S	*	*			trans	-9.8	126.9	137.6	0	0	0	0	0	116.7
86	D	23.9	Very low	23.8	Very low	147 Å²	147	143.9 Å²	143.9	79%	0.786	80%	0.795	S	S	*	*				170.9	131.8	92.8	-101.2	-30.5	0	0	0	112.3
87	S	25.3	Very low	23.8	Very low	97 Å²	97	142 Å²	142	68%	0.678	79%	0.786	S	S	*	*			trans	67.3	122.3	142.7	77	0	0	0	0	121.4
88	K	26	Very low	23.8	Very low	194 Å²	194	141 Å²	141	84%	0.843	78%	0.777	S	S	*	*			trans	67.1	101	146.3	-60.3	171.5	-176.9	177	0	117.7
89	Q	25.2	Very low	24.1	Very low	197 Å²	197	143.8 Å²	143.8	92%	0.921	78%	0.781	S	S	*	*				-163.8	142.8	118.1	-110.6	169.4	24.2	0	0	113.7
90	T	23.3	Very low	24.7	Very low	126 Å²	126	140.9 Å²	140.9	77%	0.773	77%	0.77	S	S	*	*			trans	-71.3	149.6	179.2	38	0	0	0	0	113.8
91	A	22.1	Very low	24.8	Very low	84 Å²	84	141.1 Å²	141.1	69%	0.694	77%	0.772	S	S	*	*			trans	66.7	115.6	152.8	0	0	0	0	0	117.6
92	H	24.7	Very low	24.9	Very low	177 Å²	177	141.3 Å²	141.3	82%	0.819	77%	0.769	S	S	*	*				-175.4	142.5	104.8	-101.6	-89.2	0	0	0	112.1
93	K	21.9	Very low	25.1	Very low	182 Å²	182	141.8 Å²	141.8	79%	0.791	76%	0.762	S	S	*	*			trans	-40.6	138.3	174.7	-63.7	162.4	174.7	176	0	114.7
94	I	27.8	Very low	25.3	Very low	168 Å²	168	144 Å²	144	86%	0.862	76%	0.761	S	S	*	*			trans	-127.1	118.1	153.2	-64.9	-179.9	0	0	0	109.3
95	F	21.1	Very low	25.5	Very low	164 Å²	164	144.2 Å²	144.2	72%	0.719	76%	0.756	S	S	*	*			trans	-58.2	135.9	163.9	-98.1	-111.1	0	0	0	110.8	N97	F95-N97 HydrophobicContact CD1-CB 4.28Å
96	M	29.8	Very low	25.5	Very low	200 Å²	200	146.7 Å²	146.7	99%	0.985	76%	0.757	S	S	*	*			trans	-136.4	130.1	134.6	-105.8	-157.8	155	0	0	109.5
97	N	22.1	Very low	25.8	Very low	118 Å²	118	151.2 Å²	151.2	63%	0.631	77%	0.765	S	S	*	*			trans	-125.2	161.1	-167	-159.6	13.3	0	0	0	106.1	F95	F95-N97 HydrophobicContact CD1-CB 4.28Å
98	Q	25.5	Very low	25.7	Very low	138 Å²	138	156.3 Å²	156.3	65%	0.645	78%	0.775	S	S	*	*			trans	110.8	103.9	152.7	-68.4	-177.4	6.9	0	0	120.6
99	Y	28.6	Very low	25.6	Very low	196 Å²	196	159 Å²	159	77%	0.769	78%	0.78	S	S	*	*			trans	91.7	150.5	139	-63.7	-60.9	0	0	0	121
100	P	36.9	Very low	25.6	Very low	99 Å²	99	155.2 Å²	155.2	64%	0.643	78%	0.776	S	S	*	*				-138.8	153.5	-56.6	33.1	-13.7	0	0	0	116.9
101	L	23.5	Very low	25.8	Very low	144 Å²	144	160.4 Å²	160.4	75%	0.754	78%	0.781	S	S	*	*			trans	43.1	120.2	133.5	-74.7	84	0	0	0	122.8
102	H	24.5	Very low	26	Very low	154 Å²	154	162.2 Å²	162.2	71%	0.713	79%	0.786	S	S	*	*				138.3	140.1	92	-115.6	-125.5	0	0	0	118
103	I	27.1	Very low	25.8	Very low	136 Å²	136	162 Å²	162	70%	0.697	79%	0.785	S	S	*	*			trans	87.6	90.2	150.9	-63.4	159.9	0	0	0	116.5
104	T	24.6	Very low	26.2	Very low	119 Å²	119	161.7 Å²	161.7	73%	0.73	79%	0.791	S	S	*	*				81.3	115.9	75	62.6	0	0	0	0	115.7
105	S	28.8	Very low	26.1	Very low	103 Å²	103	160.9 Å²	160.9	72%	0.72	79%	0.789	S	S	*	*				147.2	103.3	112.9	70.5	0	0	0	0	113.2
106	D	23.3	Very low	26.3	Very low	137 Å²	137	156.5 Å²	156.5	73%	0.733	79%	0.79	S	S	*	*			trans	30.9	109.9	133.7	-57.1	-51.1	0	0	0	121.5
107	Y	30.8	Very low	26.2	Very low	243 Å²	243	155.9 Å²	155.9	95%	0.953	78%	0.784	S	S	*	*			trans	-139.8	85.1	130.3	-80.5	-78	0	0	0	109.5
108	K	22.3	Very low	26.4	Very low	204 Å²	204	155.1 Å²	155.1	89%	0.887	79%	0.788	S	S	*	*			trans	-82.8	121.3	161	-105.4	178.4	176.5	175.9	0	108.3
109	R	24.7	Very low	26.2	Very low	249 Å²	249	155.7 Å²	155.7	94%	0.94	80%	0.796	S	S	*	*			trans	-125.6	134.9	160.4	-137.5	179.7	-163.8	-167.9	4.4	109.2
110	S	25.1	Very low	26.3	Very low	119 Å²	119	154.4 Å²	154.4	83%	0.832	80%	0.797	S	S	*	*	P	Polyproline II helix	trans	-76.1	145	-158.8	-27.4	0	0	0	0	114
111	R	26.4	Very low	25.8	Very low	234 Å²	234	156.5 Å²	156.5	88%	0.883	80%	0.803	S	S	*	*	P	Polyproline II helix	trans	-83.7	137.1	173.1	-171.8	178.9	-169.2	177.1	2.1	109.7
112	P	27.4	Very low	25.8	Very low	123 Å²	123	157.3 Å²	157.3	80%	0.799	81%	0.807	S	S	*	*	P	Polyproline II helix	trans	-69.9	135.6	178.5	-18.4	31.7	0	0	0	113
113	E	20.8	Very low	26	Very low	171 Å²	171	158.9 Å²	158.9	80%	0.799	82%	0.815	S	S	*	*	P	Polyproline II helix	trans	-58.2	134.2	172.4	-60.4	-99.3	138	0	0	111.9
114	L	30	Very low	25.9	Very low	177 Å²	177	159.1 Å²	159.1	93%	0.927	82%	0.817	S	S	*	*			trans	-129.6	104.6	153.6	-141.5	100.8	0	0	0	108
115	N	24.1	Very low	26	Very low	151 Å²	151	161.5 Å²	161.5	81%	0.807	82%	0.822	S	S	*	*			trans	-59.1	141.4	165.6	-97.1	-6.7	0	0	0	110.8
116	G	26.7	Very low	25.8	Very low	72 Å²	72	161.3 Å²	161.3	74%	0.742	82%	0.821	S	S	*	*			trans	157.6	69.2	164.4	0	0	0	0	0	116.5
117	Q	26.9	Very low	26.1	Very low	186 Å²	186	162.8 Å²	162.8	87%	0.869	83%	0.827	S	S	*	*			trans	46.5	116.9	134.6	-68.3	173.4	-12.3	0	0	121.8
118	S	26.2	Very low	26	Very low	102 Å²	102	156.1 Å²	156.1	71%	0.713	82%	0.816	S	S	*	*			trans	67.7	113.9	133.2	60.8	0	0	0	0	121.7
119	N	22.1	Very low	26.4	Very low	150 Å²	150	152 Å²	152	80%	0.802	81%	0.808	S	S	*	*				34.7	117.6	128.8	-63.4	-4.8	0	0	0	117.7
120	E	29.2	Very low	26.6	Very low	169 Å²	169	146 Å²	146	79%	0.79	80%	0.802	S	S	*	*				-179.8	141.8	88.8	-86.8	-168.6	177.9	0	0	111
121	N	27.3	Very low	26.9	Very low	144 Å²	144	144.5 Å²	144.5	77%	0.77	80%	0.796	S	S	*	*			trans	67.4	103.3	154.1	-56.1	-27.7	0	0	0	120.4	E123	N121-E123 PolarHBondContact O-N 3.36Å
122	L	24.6	Very low	27	Very low	161 Å²	161	136.6 Å²	136.6	84%	0.843	78%	0.781	S	S	*	*			trans	-58.6	106	160.7	-174.4	74.2	0	0	0	110.7
123	E	28.4	Very low	27	Very low	187 Å²	187	136.7 Å²	136.7	87%	0.874	78%	0.783	S	S	*	*			trans	-116.4	114.8	155	-75.7	-161.6	163.1	0	0	109	N121	N121-E123 PolarHBondContact O-N 3.36Å
124	D	24.5	Very low	27.4	Very low	141 Å²	141	138.6 Å²	138.6	75%	0.754	78%	0.784	S	S	*	*			trans	-55.2	130	162.8	-72	-49.1	0	0	0	109.7
125	M	25.6	Very low	27.4	Very low	169 Å²	169	136.2 Å²	136.2	83%	0.833	77%	0.772	S	S	*	*				167.4	140.3	127.2	-170	57.7	67.5	0	0	111.7
126	S	25.9	Very low	27.6	Very low	98 Å²	98	133.9 Å²	133.9	69%	0.685	77%	0.766	S	S	*	*			trans	76.9	80.8	164.7	64.9	0	0	0	0	117.7	S128	S126-S128 PolarHBondContact O-N 2.8Å
127	I	30	Very low	27.6	Very low	168 Å²	168	135.9 Å²	135.9	86%	0.862	77%	0.766	S	S	*	*			trans	-58.5	91.2	147.2	-58.4	163.2	0	0	0	106.4	T129	I127-T129 PolarHBondContact O-N 2.89Å
128	S	28.6	Very low	27.7	Very low	103 Å²	103	134.4 Å²	134.4	72%	0.72	76%	0.764	S	S	*	*			trans	-64.3	104.2	166.5	48.4	0	0	0	0	107.1	S126	S126-S128 PolarHBondContact O-N 2.8Å
129	T	29.5	Very low	27.7	Very low	119 Å²	119	137.2 Å²	137.2	73%	0.73	77%	0.765	S	S	*	*			trans	-50.7	129.6	161.9	36.9	0	0	0	0	107.5	I127 A131	I127-T129 PolarHBondContact O-N 2.89Å; T129-A131 PolarHBondContact O-N 2.81Å
130	P	29.5	Very low	28.3	Very low	123 Å²	123	134.9 Å²	134.9	80%	0.799	76%	0.758	S	S	*	*			trans	-60.3	131.4	-175.1	24	-31.2	0	0	0	107.9	A132	P130-A132 PolarHBondContact O-N 3.31Å
131	A	30.3	Very low	28.5	Very low	87 Å²	87	135.7 Å²	135.7	72%	0.719	76%	0.759	S	S	*	*			trans	-40.9	113.3	-179.8	0	0	0	0	0	109.5	T129 C133	T129-A131 PolarHBondContact O-N 2.81Å; A131-C133 PolarHBondContact O-N 3.43Å
132	A	30.4	Very low	29.1	Very low	67 Å²	67	135.9 Å²	135.9	55%	0.554	76%	0.76	S	S	*	*			trans	-48.4	111.8	166.2	0	0	0	0	0	105.5	P130 Y134	P130-A132 PolarHBondContact O-N 3.31Å; A132-Y134 HydrophobicContact CB-CD2 4.38Å; A132-Y134 HydrophobicContact CB-CE2 4.07Å; A132-Y134 WeakPolarHBondContact O-CD2 3.47Å; A132-Y134 PolarHBondContact O-N 2.98Å
133	C	26.2	Very low	30	Very low	126 Å²	126	130 Å²	130	85%	0.851	74%	0.739	S	S	*	*			trans	-66.6	82.4	173.4	-72.6	0	0	0	0	106	A131 L135	A131-C133 PolarHBondContact O-N 3.43Å; C133-L135 VanDerWaalsContact C-N 3.35Å; C133-L135 PolarHBondContact O-N 3.22Å
134	Y	29.8	Very low	30.7	Very low	210 Å²	210	126.6 Å²	126.6	82%	0.824	73%	0.726	S	S	*	*			trans	-54.1	108.7	159.3	-68.9	-80.5	0	0	0	104.7	A132 C136	A132-Y134 HydrophobicContact CB-CD2 4.38Å; A132-Y134 HydrophobicContact CB-CE2 4.07Å; A132-Y134 WeakPolarHBondContact O-CD2 3.47Å; A132-Y134 PolarHBondContact O-N 2.98Å; Y134-C136 PolarHBondContact O-N 3.47Å
135	L	29.6	Very low	31.9	Very low	127 Å²	127	125.6 Å²	125.6	67%	0.665	71%	0.712	S	S	*	*			trans	-52.7	101.8	163.8	-79.9	161.9	0	0	0	105.5	T44 C133	T44-L135 HydrophobicContact CG2-CB 4.26Å; T44-L135 HydrophobicContact CG2-CD1 3.73Å; C133-L135 VanDerWaalsContact C-N 3.35Å; C133-L135 PolarHBondContact O-N 3.22Å
136	C	27.5	Very low	33.2	Very low	103 Å²	103	119 Å²	119	70%	0.696	68%	0.682	S	S	*	*			trans	-52.3	130.4	173.1	-171.6	0	0	0	0	106.5	Y134 L138	Y134-C136 PolarHBondContact O-N 3.47Å; C136-L138 VanDerWaalsContact C-N 3.33Å; C136-L138 PolarHBondContact O-N 2.87Å
137	P	26.6	Very low	34.4	Very low	114 Å²	114	117.8 Å²	117.8	74%	0.74	67%	0.668	S	S	*	*			trans	-55.4	102.3	175.7	-21.5	31.3	0	0	0	107.7	Q139	P137-Q139 VanDerWaalsContact C-N 3.33Å; P137-Q139 PolarHBondContact O-N 3.41Å
138	L	29.1	Very low	35.5	Very low	155 Å²	155	110.5 Å²	110.5	81%	0.812	63%	0.63	S	S	*	*			trans	-63.1	103.4	174.8	-80.4	163.1	0	0	0	105.5	C136	C136-L138 VanDerWaalsContact C-N 3.33Å; C136-L138 PolarHBondContact O-N 2.87Å
139	Q	27	Very low	36.6	Very low	160 Å²	160	108.5 Å²	108.5	75%	0.748	62%	0.616	S	S	*	*			trans	-46.7	141.2	164.8	-73.7	-72.9	-10.6	0	0	107.9	P137 K141	P137-Q139 VanDerWaalsContact C-N 3.33Å; P137-Q139 PolarHBondContact O-N 3.41Å; Q139-K141 VanDerWaalsContact C-N 3.25Å; Q139-K141 PolarHBondContact O-N 3.36Å
140	P	34.7	Very low	37.6	Very low	101 Å²	101	111.2 Å²	111.2	66%	0.656	62%	0.618	S	S	*	*			trans	-64.9	88.4	-174.3	27.9	-33.3	0	0	0	108.9	N142	P140-N142 PolarHBondContact O-N 3.45Å
141	K	32.6	Very low	38.7	Very low	187 Å²	187	110 Å²	110	81%	0.813	60%	0.604	S	S	*	*			trans	-55.5	115.6	152.3	-76	-173.6	175.2	-178.9	0	103.6	Q139 G143	Q139-K141 VanDerWaalsContact C-N 3.25Å; Q139-K141 PolarHBondContact O-N 3.36Å; K141-G143 VanDerWaalsContact C-N 3.35Å; K141-G143 WeakPolarHBondContact O-CA 3.33Å; K141-G143 PolarHBondContact O-N 3.19Å
142	N	41.4	Very low	39.7	Very low	148 Å²	148	106.6 Å²	106.6	79%	0.791	57%	0.574	S	S	*	*			trans	-28.5	101.8	175.6	-72.5	-16.9	0	0	0	108.3	P140 L144	P140-N142 PolarHBondContact O-N 3.45Å; N142-L144 PolarHBondContact O-N 2.91Å
143	G	43	Very low	40.7	Very low	38 Å²	38	112.6 Å²	112.6	39%	0.392	59%	0.591	S	S	.	*			trans	-50.7	132.7	-170	0	0	0	0	0	106.8	K141 R145	K141-G143 VanDerWaalsContact C-N 3.35Å; K141-G143 WeakPolarHBondContact O-CA 3.33Å; K141-G143 PolarHBondContact O-N 3.19Å; G143-R145 PolarHBondContact O-N 3.47Å
144	L	42.3	Very low	42.3	Very low	114 Å²	114	109 Å²	109	60%	0.597	57%	0.567	S	S	*	*			trans	-53.1	92.7	179.7	-173.3	83.4	0	0	0	107.2	N142 S146	N142-L144 PolarHBondContact O-N 2.91Å; L144-S146 PolarHBondContact O-N 2.8Å; L144-S146 VanDerWaalsContact O-N 3.13Å
145	R	51	Low	44.2	Very low	121 Å²	121	105.4 Å²	105.4	46%	0.457	56%	0.558	S	S	.	*			trans	-57.4	124.5	169.5	-88.6	-171.5	168	-147.3	-6.5	103.8	G143 D147 A413	G143-R145 PolarHBondContact O-N 3.47Å; R145-D147 PolarHBondContact O-N 3.46Å; R145-A413 PolarHBondContact NH2-O 3.01Å
146	S	52.8	Low	46.8	Very low	31 Å²	31	99.9 Å²	99.9	22%	0.217	53%	0.529	C	S	.	.			trans	-69.8	80.4	163.7	51.5	0	0	0	0	105.4	L144 L148 R385	L144-S146 PolarHBondContact O-N 2.8Å; L144-S146 VanDerWaalsContact O-N 3.13Å; S146-L148 PolarHBondContact O-N 3.43Å; S146-R385 VanDerWaalsContact CB-NH2 3.31Å; S146-R385 PolarHBondContact OG-NH2 3.34Å
147	D	51.1	Low	49.7	Very low	72 Å²	72	97 Å²	97	39%	0.385	51%	0.508	S	S	.	.			trans	-67.9	108	-165.6	-150.7	7	0	0	0	106.9	R145 S149 K150	R145-D147 PolarHBondContact O-N 3.46Å; D147-S149 VanDerWaalsContact CB-OG 3.32Å; D147-S149 WeakPolarHBondContact CB-OG 3.39Å; D147-S149 PolarHBondContact O-N 2.97Å; D147-S149 PolarHBondContact OD1-OG 2.9Å; D147-S149 PolarHBondContact OD2-OG 2.89Å; D147-K150 PolarHBondContact O-N 3.47Å
148	L	52.8	Low	52.7	Low	14 Å²	14	91.8 Å²	91.8	7%	0.073	47%	0.474	C	S	.	.	G	3₁₀ helix	trans	-57.5	-16.5	172.8	-106.3	67.6	0	0	0	111.2	S146 K150 I151 C152 I156 V382 V415	S146-L148 PolarHBondContact O-N 3.43Å; L148-K150 PolarHBondContact O-N 3.34Å; L148-K150 VanDerWaalsContact O-N 3.08Å; L148-I151 CarbonylContact O-C 3.15Å; L148-I151 WeakPolarHBondContact O-CA 3.41Å; L148-I151 PolarHBondContact O-N 2.95Å; L148-C152 PolarHBondContact O-N 3.46Å; L148-I156 HydrophobicContact CD2-CD1 3.84Å; L148-V382 HydrophobicContact CD2-CG2 3.84Å; L148-V415 HydrophobicContact CD1-CB 4.04Å; L148-V415 HydrophobicContact CD1-CG1 3.34Å; L148-V415 HydrophobicContact CD1-CG2 4.19Å; L148-V415 HydrophobicContact CD2-CG1 3.46Å; L148-V415 VanDerWaalsContact CD2-CG1 3.46Å; L148-V415 HydrophobicContact CG-CG1 3.91Å; L148-V415 PolarHBondContact N-O 2.89Å
149	S	50.9	Low	55.6	Low	61 Å²	61	87.5 Å²	87.5	43%	0.427	45%	0.449	S	S	.	.	G	3₁₀ helix	trans	-50.1	-28.6	169.7	73.8	0	0	0	0	113.7	D147 C152	D147-S149 VanDerWaalsContact CB-OG 3.32Å; D147-S149 WeakPolarHBondContact CB-OG 3.39Å; D147-S149 PolarHBondContact O-N 2.97Å; D147-S149 PolarHBondContact OD1-OG 2.9Å; D147-S149 PolarHBondContact OD2-OG 2.89Å; S149-C152 CarbonylContact C-O 3.56Å; S149-C152 WeakPolarHBondContact CA-O 3.3Å
150	K	50.6	Low	58.6	Low	177 Å²	177	83 Å²	83	77%	0.77	43%	0.43	S	S	*	.	G	3₁₀ helix	trans	-78.7	-19.8	176.4	-65.3	-175.3	-178.9	179.4	0	113.7	D147 L148	D147-K150 PolarHBondContact O-N 3.47Å; L148-K150 PolarHBondContact O-N 3.34Å; L148-K150 VanDerWaalsContact O-N 3.08Å
151	I	52.9	Low	61.3	Low	97 Å²	97	83.3 Å²	83.3	50%	0.497	43%	0.434	S	S	.	.	T	Hydrogen-bonded Turn	trans	-106.6	-42.5	-174.4	-63.3	176	0	0	0	110.6	L148 L381	L148-I151 CarbonylContact O-C 3.15Å; L148-I151 WeakPolarHBondContact O-CA 3.41Å; L148-I151 PolarHBondContact O-N 2.95Å; I151-L381 HydrophobicContact CG2-CD2 3.3Å; I151-L381 HydrophobicContact CG2-CG 4.43Å
152	C	50.6	Low	64.2	Low	15 Å²	15	76.4 Å²	76.4	10%	0.101	41%	0.406	C	S	.	.			trans	-112.1	117.1	173.1	-84.5	0	0	0	0	107.9	L148 S149 S154 I156	L148-C152 PolarHBondContact O-N 3.46Å; S149-C152 CarbonylContact C-O 3.56Å; S149-C152 WeakPolarHBondContact CA-O 3.3Å; C152-S154 PolarHBondContact O-N 2.93Å; C152-I156 HydrophobicContact CB-CD1 4.4Å
153	H	52.4	Low	66.7	Low	193 Å²	193	69.8 Å²	69.8	89%	0.894	37%	0.371	S	S	*	.	S	Bend	trans	-68.7	16.6	171.2	-62.4	-70.1	0	0	0	113.6
154	S	59.9	Low	69.2	Low	52 Å²	52	71.3 Å²	71.3	36%	0.364	37%	0.37	S	S	.	.	S	Bend	trans	-134.4	136.8	-173.5	62	0	0	0	0	111.2	C152 I156	C152-S154 PolarHBondContact O-N 2.93Å; S154-I156 PolarHBondContact O-N 3.18Å
155	H	70.4	Confident	71.6	Confident	134 Å²	134	69.4 Å²	69.4	62%	0.62	36%	0.36	S	S	*	.			trans	-60.9	127.1	170.8	-68.4	-93.3	0	0	0	110.2	E418	H155-E418 IonicContact CE1-OE1 3.63Å; H155-E418 IonicContact CG-OE1 3.78Å; H155-E418 IonicContact ND1-OE1 2.93Å; H155-E418 PolarHBondContact ND1-OE1 3.32Å; H155-E418 IonicContact ND1-OE2 2.76Å
156	I	83.5	Confident	73.8	Confident	10 Å²	10	70.2 Å²	70.2	5%	0.051	37%	0.373	C	S	.	.			trans	-102.5	116.9	177.2	-60.3	177	0	0	0	107.8	L148 C152 S154 V318 I417 E418	L148-I156 HydrophobicContact CD2-CD1 3.84Å; C152-I156 HydrophobicContact CB-CD1 4.4Å; S154-I156 PolarHBondContact O-N 3.18Å; I156-V318 HydrophobicContact CG2-CG1 3.23Å; I156-I417 HydrophobicContact CB-CG1 4.48Å; I156-I417 HydrophobicContact CG2-CG1 4.13Å; I156-E418 PolarHBondContact O-N 3.47Å
157	V	87.4	Confident	75.8	Confident	43 Å²	43	72.4 Å²	72.4	26%	0.261	38%	0.377	S	S	.	.	B	Isolated β-bridge	trans	-116.1	130.6	-174.3	-174.5	0	0	0	0	110.3	K159 S321 E418	V157-K159 PolarHBondContact O-N 2.98Å; V157-S321 VanDerWaalsContact O-CB 3.27Å; V157-S321 WeakPolarHBondContact O-CB 3.47Å; V157-S321 PolarHBondContact O-OG 2.91Å; V157-E418 HydrophobicContact CG2-CB 4.22Å
158	C	89.9	Confident	78	Confident	5 Å²	5	69 Å²	69	3%	0.034	36%	0.359	C	S	.	.			trans	-82.6	108.9	168.2	-167.3	0	0	0	0	109.5	C317 V318 I417 E418 L420	C158-C317 VanDerWaalsContact SG-SG 3.68Å; C158-V318 HydrophobicContact CB-CG2 3.84Å; C158-I417 HydrophobicContact CB-CG2 4.11Å; C158-E418 PolarHBondContact N-O 3.48Å; C158-L420 HydrophobicContact CB-CD2 4.16Å
159	K	90.2	Very high	80.1	Confident	64 Å²	64	73.2 Å²	73.2	28%	0.278	38%	0.378	S	S	.	.			trans	-88.7	114.3	178.1	-75.2	178.7	-178.2	178.5	0	110.1	V157 S161 L162 C317 S321	V157-K159 PolarHBondContact O-N 2.98Å; K159-S161 PolarHBondContact O-N 3.25Å; K159-S161 VanDerWaalsContact O-N 3.1Å; K159-L162 HydrophobicContact CB-CD1 3.97Å; K159-L162 HydrophobicContact CB-CG 4.14Å; K159-L162 HydrophobicContact CD-CD1 4.17Å; K159-L162 PolarHBondContact O-N 2.8Å; K159-C317 PolarHBondContact O-SG 3.46Å; K159-S321 WeakPolarHBondContact CD-OG 3.48Å; K159-S321 WeakPolarHBondContact CG-OG 3.45Å
160	L	90.6	Very high	82.3	Confident	66 Å²	66	74 Å²	74	35%	0.346	38%	0.377	S	S	.	.	G	3₁₀ helix	trans	-55.6	-30.9	-178.5	-166.8	59.9	0	0	0	113.9	L162 L163 P422 L423 L426	L160-L162 PolarHBondContact O-N 2.96Å; L160-L163 HydrophobicContact CD1-CD2 3.85Å; L160-L163 WeakPolarHBondContact O-CB 3.21Å; L160-L163 PolarHBondContact O-N 2.94Å; L160-P422 HydrophobicContact CD2-CB 4.23Å; L160-L423 HydrophobicContact CD1-CD1 3.83Å; L160-L426 HydrophobicContact CD1-CD2 3.59Å; L160-L426 HydrophobicContact CG-CD2 4.44Å
161	S	91.7	Very high	84.5	Confident	107 Å²	107	66.4 Å²	66.4	75%	0.748	35%	0.345	S	S	*	.	G	3₁₀ helix	trans	-66.8	-19.3	178.6	53.6	0	0	0	0	114.6	K159	K159-S161 PolarHBondContact O-N 3.25Å; K159-S161 VanDerWaalsContact O-N 3.1Å
162	L	93.3	Very high	86.6	Confident	42 Å²	42	62.8 Å²	62.8	22%	0.22	33%	0.327	C	S	.	.	G	3₁₀ helix	trans	-96.4	-1.7	179.7	-57.7	176.2	0	0	0	112.6	K159 L160 K320 S321 I324	K159-L162 HydrophobicContact CB-CD1 3.97Å; K159-L162 HydrophobicContact CB-CG 4.14Å; K159-L162 HydrophobicContact CD-CD1 4.17Å; K159-L162 PolarHBondContact O-N 2.8Å; L160-L162 PolarHBondContact O-N 2.96Å; L162-K320 HydrophobicContact CB-CB 4.5Å; L162-K320 HydrophobicContact CD1-CB 4.11Å; L162-S321 VanDerWaalsContact CD1-CA 3.41Å; L162-I324 HydrophobicContact CD1-CD1 3.74Å; L162-I324 HydrophobicContact CD2-CD1 3.78Å; L162-I324 HydrophobicContact CG-CD1 4.42Å
163	L	93.6	Very high	88.8	Confident	10 Å²	10	65.9 Å²	65.9	5%	0.052	35%	0.349	C	S	.	.	S	Bend	trans	-73.8	133.5	-178.5	-164	70.1	0	0	0	110.5	L160 N165 L168 L313 F314 C317 L423 L426	L160-L163 HydrophobicContact CD1-CD2 3.85Å; L160-L163 WeakPolarHBondContact O-CB 3.21Å; L160-L163 PolarHBondContact O-N 2.94Å; L163-N165 PolarHBondContact O-N 3.49Å; L163-N165 PolarHBondContact O-ND2 3.31Å; L163-L168 HydrophobicContact CD2-CD2 3.79Å; L163-L313 HydrophobicContact CD1-CD2 3.26Å; L163-L313 HydrophobicContact CG-CD2 4.01Å; L163-F314 HydrophobicContact CD1-CD1 3.93Å; L163-F314 HydrophobicContact CD1-CE1 4.28Å; L163-C317 HydrophobicContact CD1-CB 3.85Å; L163-L423 HydrophobicContact CD1-CD1 4.34Å; L163-L423 HydrophobicContact CD2-CD1 3.38Å; L163-L426 HydrophobicContact CD2-CD2 3.9Å
164	D	94.8	Very high	90.8	Very high	70 Å²	70	60.6 Å²	60.6	37%	0.374	32%	0.323	S	S	.	.			trans	-74	93.1	170	-173.5	-18.7	0	0	0	109.2	D166 R167 L168	D164-D166 VanDerWaalsContact C-N 3.33Å; D164-D166 PolarHBondContact OD1-N 3.32Å; D164-R167 HydrophobicContact CB-CB 4.03Å; D164-R167 WeakPolarHBondContact OD1-CB 3.37Å; D164-R167 PolarHBondContact OD1-N 2.98Å; D164-R167 WeakPolarHBondContact OD2-CB 3.1Å; D164-L168 WeakPolarHBondContact O-CB 3.39Å; D164-L168 PolarHBondContact O-N 2.99Å
165	N	93.7	Very high	92.5	Very high	73 Å²	73	58.1 Å²	58.1	39%	0.39	31%	0.306	S	S	.	.	H	α-helix	trans	-65.4	-35.9	-177.1	-73.2	-70.9	0	0	0	112	L163 L168 Q169	L163-N165 PolarHBondContact O-N 3.49Å; L163-N165 PolarHBondContact O-ND2 3.31Å; N165-L168 PolarHBondContact O-N 3.15Å; N165-Q169 VanDerWaalsContact O-CG 3.3Å; N165-Q169 WeakPolarHBondContact O-CG 3.23Å; N165-Q169 PolarHBondContact O-N 2.94Å
166	D	95.9	Very high	93.5	Very high	138 Å²	138	58.3 Å²	58.3	74%	0.738	31%	0.305	S	S	*	.	H	α-helix	trans	-67.2	-45.4	-179.7	-66.2	-30.2	0	0	0	110.6	D164 L168 Q169 N170	D164-D166 VanDerWaalsContact C-N 3.33Å; D164-D166 PolarHBondContact OD1-N 3.32Å; D166-L168 VanDerWaalsContact C-N 3.33Å; D166-L168 PolarHBondContact O-N 3.17Å; D166-Q169 PolarHBondContact O-N 3.47Å; D166-N170 WeakPolarHBondContact O-CB 3.42Å; D166-N170 PolarHBondContact O-N 2.98Å
167	R	96.2	Very high	93.9	Very high	78 Å²	78	63.3 Å²	63.3	29%	0.294	33%	0.331	S	S	.	.	H	α-helix	trans	-64	-39.3	174.6	-168.6	-174.8	164.5	-165.8	-3.4	111.3	D164 N170 L171 L313 D316	D164-R167 HydrophobicContact CB-CB 4.03Å; D164-R167 WeakPolarHBondContact OD1-CB 3.37Å; D164-R167 PolarHBondContact OD1-N 2.98Å; D164-R167 WeakPolarHBondContact OD2-CB 3.1Å; R167-N170 PolarHBondContact O-N 3.27Å; R167-L171 WeakPolarHBondContact O-CG 3Å; R167-L171 PolarHBondContact O-N 3.32Å; R167-L313 HydrophobicContact CB-CD1 3.81Å; R167-L313 HydrophobicContact CG-CD1 3.7Å; R167-D316 IonicContact NH1-OD2 3.82Å; R167-D316 PolarHBondContact NH1-OD2 3.08Å
168	L	97	Very high	94.2	Very high	0 Å²	0	62.7 Å²	62.7	0%	0	32%	0.324	C	S	.	.	H	α-helix	trans	-60.8	-50	176.1	177.2	67.9	0	0	0	111.3	L163 D164 N165 D166 N170 L171 L172 F310 L313 F314 L426	L163-L168 HydrophobicContact CD2-CD2 3.79Å; D164-L168 WeakPolarHBondContact O-CB 3.39Å; D164-L168 PolarHBondContact O-N 2.99Å; N165-L168 PolarHBondContact O-N 3.15Å; D166-L168 VanDerWaalsContact C-N 3.33Å; D166-L168 PolarHBondContact O-N 3.17Å; L168-N170 VanDerWaalsContact C-N 3.3Å; L168-N170 PolarHBondContact O-N 3.49Å; L168-L171 PolarHBondContact O-N 3.03Å; L168-L172 HydrophobicContact CD1-CD1 4.19Å; L168-L172 HydrophobicContact CD1-CG 4.2Å; L168-L172 HydrophobicContact CD2-CD1 4.34Å; L168-L172 HydrophobicContact CG-CD1 3.87Å; L168-L172 HydrophobicContact CG-CG 4.3Å; L168-L172 WeakPolarHBondContact O-CB 3.3Å; L168-L172 WeakPolarHBondContact O-CG 3.47Å; L168-L172 PolarHBondContact O-N 3.4Å; L168-F310 HydrophobicContact CD1-CD1 4.34Å; L168-F310 HydrophobicContact CD1-CE1 4.46Å; L168-L313 HydrophobicContact CB-CD1 4.08Å; L168-F314 HydrophobicContact CD1-CE1 4.12Å; L168-F314 HydrophobicContact CD1-CZ 4.3Å; L168-L426 HydrophobicContact CD2-CD2 3.71Å; L168-L426 HydrophobicContact CD2-CG 4.12Å
169	Q	96.4	Very high	94.3	Very high	102 Å²	102	65 Å²	65	48%	0.477	33%	0.334	S	S	.	.	H	α-helix	trans	-63.3	-37.4	-179.7	-68.5	-60.5	-24	0	0	111.8	N165 D166 L172 S173	N165-Q169 VanDerWaalsContact O-CG 3.3Å; N165-Q169 WeakPolarHBondContact O-CG 3.23Å; N165-Q169 PolarHBondContact O-N 2.94Å; D166-Q169 PolarHBondContact O-N 3.47Å; Q169-L172 PolarHBondContact O-N 3.47Å; Q169-S173 WeakPolarHBondContact O-CB 3.21Å; Q169-S173 PolarHBondContact O-N 3.1Å
170	N	96.9	Very high	94.3	Very high	78 Å²	78	62.3 Å²	62.3	42%	0.417	32%	0.323	S	S	.	.	H	α-helix	trans	-59.7	-49.4	173.3	-168.7	-44.8	0	0	0	111.4	D166 R167 L168 L172 S173 K174	D166-N170 WeakPolarHBondContact O-CB 3.42Å; D166-N170 PolarHBondContact O-N 2.98Å; R167-N170 PolarHBondContact O-N 3.27Å; L168-N170 VanDerWaalsContact C-N 3.3Å; L168-N170 PolarHBondContact O-N 3.49Å; N170-L172 PolarHBondContact O-N 3.16Å; N170-S173 PolarHBondContact O-N 3.32Å; N170-S173 PolarHBondContact O-OG 2.88Å; N170-K174 PolarHBondContact O-N 3.33Å; N170-K174 WeakPolarHBondContact OD1-CE 2.97Å; N170-K174 PolarHBondContact OD1-NZ 3.28Å; N170-K174 VanDerWaalsContact OD1-NZ 3.13Å
171	L	97.1	Very high	94.3	Very high	18 Å²	18	64.7 Å²	64.7	9%	0.094	34%	0.336	C	S	.	.	H	α-helix	trans	-63.5	-43.2	178.4	-66.2	176.1	0	0	0	111.9	R167 L168 S173 K174 E175 V305 D309 F310 L313	R167-L171 WeakPolarHBondContact O-CG 3Å; R167-L171 PolarHBondContact O-N 3.32Å; L168-L171 PolarHBondContact O-N 3.03Å; L171-S173 VanDerWaalsContact C-N 3.31Å; L171-S173 PolarHBondContact O-N 3.22Å; L171-K174 PolarHBondContact O-N 2.81Å; L171-K174 VanDerWaalsContact O-N 3.17Å; L171-E175 PolarHBondContact O-N 2.93Å; L171-V305 HydrophobicContact CD2-CG1 3.85Å; L171-V305 HydrophobicContact CD2-CG2 4.06Å; L171-D309 HydrophobicContact CD1-CB 4.2Å; L171-D309 HydrophobicContact CD2-CB 3.9Å; L171-F310 HydrophobicContact CB-CD1 3.99Å; L171-F310 HydrophobicContact CB-CE1 3.28Å; L171-F310 HydrophobicContact CB-CE2 4.38Å; L171-F310 HydrophobicContact CB-CZ 3.54Å; L171-F310 HydrophobicContact CD1-CD1 4.03Å; L171-F310 HydrophobicContact CD1-CE1 4.2Å; L171-F310 HydrophobicContact CD1-CG 4.47Å; L171-F310 HydrophobicContact CG-CE1 4.37Å; L171-L313 HydrophobicContact CD1-CB 4.42Å; L171-L313 HydrophobicContact CD1-CD1 3.84Å
172	L	96.7	Very high	94.3	Very high	20 Å²	20	59.8 Å²	59.8	11%	0.105	30%	0.302	C	S	.	.	H	α-helix	trans	-60.5	-39	176.6	-72.4	174.2	0	0	0	112.2	L168 Q169 N170 K174 E175 F310 V405	L168-L172 HydrophobicContact CD1-CD1 4.19Å; L168-L172 HydrophobicContact CD1-CG 4.2Å; L168-L172 HydrophobicContact CD2-CD1 4.34Å; L168-L172 HydrophobicContact CG-CD1 3.87Å; L168-L172 HydrophobicContact CG-CG 4.3Å; L168-L172 WeakPolarHBondContact O-CB 3.3Å; L168-L172 WeakPolarHBondContact O-CG 3.47Å; L168-L172 PolarHBondContact O-N 3.4Å; Q169-L172 PolarHBondContact O-N 3.47Å; N170-L172 PolarHBondContact O-N 3.16Å; L172-K174 VanDerWaalsContact C-N 3.26Å; L172-K174 PolarHBondContact O-N 3.21Å; L172-E175 PolarHBondContact O-N 2.75Å; L172-F310 HydrophobicContact CD2-CE1 4.11Å; L172-F310 HydrophobicContact CG-CE1 4.3Å; L172-V405 HydrophobicContact CD2-CG2 3.47Å; L172-V405 VanDerWaalsContact CD2-CG2 3.47Å
173	S	96.2	Very high	94.2	Very high	81 Å²	81	60.1 Å²	60.1	57%	0.566	31%	0.31	S	S	*	.	H	α-helix	trans	-65.5	-29.2	178	74.7	0	0	0	0	113.2	Q169 N170 L171	Q169-S173 WeakPolarHBondContact O-CB 3.21Å; Q169-S173 PolarHBondContact O-N 3.1Å; N170-S173 PolarHBondContact O-N 3.32Å; N170-S173 PolarHBondContact O-OG 2.88Å; L171-S173 VanDerWaalsContact C-N 3.31Å; L171-S173 PolarHBondContact O-N 3.22Å
174	K	95.2	Very high	94.2	Very high	82 Å²	82	63.8 Å²	63.8	36%	0.357	33%	0.326	S	S	.	.	H	α-helix	trans	-94.7	-17.1	-178.8	-69.1	176.6	-180	172.9	0	113.6	N170 L171 L172 F176 I177 Y178 V305	N170-K174 PolarHBondContact O-N 3.33Å; N170-K174 WeakPolarHBondContact OD1-CE 2.97Å; N170-K174 PolarHBondContact OD1-NZ 3.28Å; N170-K174 VanDerWaalsContact OD1-NZ 3.13Å; L171-K174 PolarHBondContact O-N 2.81Å; L171-K174 VanDerWaalsContact O-N 3.17Å; L172-K174 VanDerWaalsContact C-N 3.26Å; L172-K174 PolarHBondContact O-N 3.21Å; K174-F176 VanDerWaalsContact C-N 3.31Å; K174-F176 PolarHBondContact O-N 2.94Å; K174-I177 WeakPolarHBondContact O-CB 3.35Å; K174-I177 PolarHBondContact O-N 3.43Å; K174-Y178 HydrophobicContact CB-CD2 4.21Å; K174-Y178 HydrophobicContact CB-CE2 4.2Å; K174-Y178 WeakPolarHBondContact O-CD2 3.36Å; K174-V305 HydrophobicContact CB-CB 4.34Å; K174-V305 HydrophobicContact CB-CG2 3.82Å; K174-V305 HydrophobicContact CD-CG2 3.95Å
175	E	95	Very high	94.1	Very high	0 Å²	0	60.6 Å²	60.6	0%	0	31%	0.309	C	S	.	.	H	α-helix	trans	-48.2	-49.6	-172.9	-172.6	178.7	-158.1	0	0	113	L171 L172 I177 Y178 Q179 F310 R403 P404 V405	L171-E175 PolarHBondContact O-N 2.93Å; L172-E175 PolarHBondContact O-N 2.75Å; E175-I177 VanDerWaalsContact C-N 3.3Å; E175-I177 PolarHBondContact O-N 3.08Å; E175-Y178 PolarHBondContact O-N 3.04Å; E175-Q179 WeakPolarHBondContact O-CB 3.41Å; E175-Q179 PolarHBondContact O-N 2.86Å; E175-Q179 VanDerWaalsContact O-N 3.11Å; E175-F310 HydrophobicContact CB-CZ 4.17Å; E175-F310 HydrophobicContact CG-CE2 4.23Å; E175-F310 HydrophobicContact CG-CZ 4.25Å; E175-R403 WeakPolarHBondContact OE1-CB 3.36Å; E175-R403 IonicContact OE1-NE 3.27Å; E175-R403 IonicContact OE2-CZ 3.65Å; E175-R403 VanDerWaalsContact OE2-CZ 3.29Å; E175-R403 IonicContact OE2-NE 3.96Å; E175-R403 PolarHBondContact OE2-NE 3.1Å; E175-R403 IonicContact OE2-NH2 3.98Å; E175-R403 PolarHBondContact OE2-NH2 3.45Å; E175-P404 HydrophobicContact CG-CB 4.11Å; E175-P404 HydrophobicContact CG-CG 3.81Å; E175-P404 WeakPolarHBondContact OE1-CD 3.48Å; E175-V405 WeakPolarHBondContact OE1-CG2 3.24Å; E175-V405 PolarHBondContact OE1-N 3.24Å
176	F	92.1	Very high	94.1	Very high	137 Å²	137	61 Å²	61	60%	0.601	31%	0.306	S	S	*	.	H	α-helix	trans	-72.6	-20	-176.7	-61	-73	0	0	0	114.3	K174 Y178	K174-F176 VanDerWaalsContact C-N 3.31Å; K174-F176 PolarHBondContact O-N 2.94Å; F176-Y178 VanDerWaalsContact C-N 3.32Å
177	I	92.8	Very high	94	Very high	115 Å²	115	62 Å²	62	59%	0.59	30%	0.3	S	S	*	.	H	α-helix	trans	-71.8	-34.4	177.9	-56.4	175.9	0	0	0	110	K174 E175	K174-I177 WeakPolarHBondContact O-CB 3.35Å; K174-I177 PolarHBondContact O-N 3.43Å; E175-I177 VanDerWaalsContact C-N 3.3Å; E175-I177 PolarHBondContact O-N 3.08Å
178	Y	94	Very high	93.9	Very high	30 Å²	30	59.2 Å²	59.2	12%	0.118	29%	0.292	C	S	.	.	H	α-helix	trans	-105.4	-5.5	-172.9	-66.2	-77.6	0	0	0	114.2	K174 E175 F176 P180 N228 R232 D301 V305	K174-Y178 HydrophobicContact CB-CD2 4.21Å; K174-Y178 HydrophobicContact CB-CE2 4.2Å; K174-Y178 WeakPolarHBondContact O-CD2 3.36Å; E175-Y178 PolarHBondContact O-N 3.04Å; F176-Y178 VanDerWaalsContact C-N 3.32Å; Y178-P180 VanDerWaalsContact O-CD 3.24Å; Y178-P180 WeakPolarHBondContact O-CD 2.91Å; Y178-N228 PolarHBondContact O-ND2 2.91Å; Y178-R232 VanDerWaalsContact CD1-CZ 3.48Å; Y178-D301 WeakPolarHBondContact CE1-OD1 3.3Å; Y178-D301 WeakPolarHBondContact CE1-OD2 3.2Å; Y178-D301 VanDerWaalsContact OH-CG 3.31Å; Y178-D301 PolarHBondContact OH-OD1 3.39Å; Y178-D301 PolarHBondContact OH-OD2 2.76Å; Y178-V305 WeakPolarHBondContact CB-O 3.37Å; Y178-V305 HydrophobicContact CD2-CB 3.86Å; Y178-V305 HydrophobicContact CD2-CG2 4.16Å; Y178-V305 HydrophobicContact CE2-CB 4.48Å; Y178-V305 HydrophobicContact CE2-CG2 4.29Å; Y178-V305 HydrophobicContact CG-CB 4.37Å
179	Q	91.3	Very high	93.6	Very high	53 Å²	53	62.8 Å²	62.8	25%	0.248	31%	0.311	C	S	.	.			trans	-78.5	112.6	177.3	-172.5	174.9	8.6	0	0	110.9	E175 F402 P404	E175-Q179 WeakPolarHBondContact O-CB 3.41Å; E175-Q179 PolarHBondContact O-N 2.86Å; E175-Q179 VanDerWaalsContact O-N 3.11Å; Q179-F402 PolarHBondContact NE2-O 3.38Å; Q179-P404 HydrophobicContact CG-CG 4.44Å
180	P	90.3	Very high	93.4	Very high	9 Å²	9	61.2 Å²	61.2	6%	0.058	31%	0.309	C	S	.	.			trans	-76.2	133.1	179.1	31.6	-33.1	0	0	0	110.9	Y178 N182 D231 R232 V235 Y400	Y178-P180 VanDerWaalsContact O-CD 3.24Å; Y178-P180 WeakPolarHBondContact O-CD 2.91Å; P180-N182 PolarHBondContact O-N 3.17Å; P180-D231 HydrophobicContact CB-CB 3.79Å; P180-D231 HydrophobicContact CG-CB 3.48Å; P180-D231 VanDerWaalsContact CG-CB 3.48Å; P180-R232 HydrophobicContact CB-CG 4.32Å; P180-V235 HydrophobicContact CB-CG2 3.95Å; P180-Y400 HydrophobicContact CG-CD1 3.78Å; P180-Y400 HydrophobicContact CG-CE1 3.38Å
181	N	90.6	Very high	93.1	Very high	115 Å²	115	66 Å²	66	62%	0.615	33%	0.329	S	S	*	.			trans	-91.3	86.6	172.8	-174.6	-0.3	0	0	0	110.9	A183 F184	N181-A183 WeakPolarHBondContact OD1-CB 3.46Å; N181-A183 PolarHBondContact OD1-N 3.49Å; N181-F184 WeakPolarHBondContact O-CD1 3.16Å; N181-F184 WeakPolarHBondContact O-CE1 3.07Å
182	N	90.8	Very high	92.8	Very high	5 Å²	5	70.5 Å²	70.5	3%	0.027	36%	0.357	C	S	.	.			trans	-92	13	-176.1	-71.6	-14.4	0	0	0	114.6	P180 F184 L185 D231 V235 L397	P180-N182 PolarHBondContact O-N 3.17Å; N182-F184 PolarHBondContact O-N 3.42Å; N182-F184 VanDerWaalsContact O-N 3.1Å; N182-L185 HydrophobicContact CB-CD1 3.99Å; N182-L185 HydrophobicContact CB-CG 4.42Å; N182-L185 WeakPolarHBondContact O-CB 3.17Å; N182-L185 WeakPolarHBondContact O-CG 3.4Å; N182-L185 PolarHBondContact O-N 3.23Å; N182-L185 VanDerWaalsContact O-N 3.08Å; N182-D231 VanDerWaalsContact ND2-CB 3.28Å; N182-D231 WeakPolarHBondContact ND2-CB 3.46Å; N182-D231 PolarHBondContact ND2-OD1 2.8Å; N182-D231 PolarHBondContact OD1-O 3.43Å; N182-V235 WeakPolarHBondContact OD1-CG2 3.37Å; N182-L397 HydrophobicContact CB-CD1 3.59Å; N182-L397 HydrophobicContact CB-CD2 4.34Å; N182-L397 HydrophobicContact CB-CG 4.39Å; N182-L397 WeakPolarHBondContact ND2-CD1 3.42Å
183	A	91.4	Very high	92.5	Very high	48 Å²	48	72.2 Å²	72.2	40%	0.397	37%	0.367	S	S	.	.	G	3₁₀ helix	trans	-58.2	-29.3	-175.3	0	0	0	0	0	113	N181 L185 Y186 Y187	N181-A183 WeakPolarHBondContact OD1-CB 3.46Å; N181-A183 PolarHBondContact OD1-N 3.49Å; A183-L185 PolarHBondContact O-N 3.45Å; A183-Y186 PolarHBondContact O-N 2.93Å; A183-Y187 WeakPolarHBondContact O-CD2 3.43Å; A183-Y187 WeakPolarHBondContact O-CE2 3.36Å
184	F	92.9	Very high	92.3	Very high	88 Å²	88	74.3 Å²	74.3	39%	0.386	37%	0.372	S	S	.	.	G	3₁₀ helix	trans	-61.8	-26	179	67.6	-87.9	0	0	0	113.6	N181 N182 Y186 Y187 I234 V235	N181-F184 WeakPolarHBondContact O-CD1 3.16Å; N181-F184 WeakPolarHBondContact O-CE1 3.07Å; N182-F184 PolarHBondContact O-N 3.42Å; N182-F184 VanDerWaalsContact O-N 3.1Å; F184-Y186 PolarHBondContact O-N 3.01Å; F184-Y187 PolarHBondContact O-N 3.44Å; F184-I234 HydrophobicContact CE2-CG2 4.41Å; F184-I234 HydrophobicContact CZ-CG2 4.08Å; F184-V235 HydrophobicContact CE1-CG2 4.05Å
185	L	94.1	Very high	92.1	Very high	2 Å²	2	74.8 Å²	74.8	1%	0.01	37%	0.373	C	S	.	.	G	3₁₀ helix	trans	-64.1	-21.5	-179.6	-61.2	-179.5	0	0	0	113.2	N182 A183 Y187 V196 A198 R201 I234 L397	N182-L185 HydrophobicContact CB-CD1 3.99Å; N182-L185 HydrophobicContact CB-CG 4.42Å; N182-L185 WeakPolarHBondContact O-CB 3.17Å; N182-L185 WeakPolarHBondContact O-CG 3.4Å; N182-L185 PolarHBondContact O-N 3.23Å; N182-L185 VanDerWaalsContact O-N 3.08Å; A183-L185 PolarHBondContact O-N 3.45Å; L185-Y187 VanDerWaalsContact C-N 3.31Å; L185-V196 HydrophobicContact CD2-CB 4.44Å; L185-V196 HydrophobicContact CD2-CG1 4.34Å; L185-V196 WeakPolarHBondContact CD2-O 3.26Å; L185-A198 HydrophobicContact CB-CB 4.18Å; L185-A198 PolarHBondContact O-N 2.88Å; L185-R201 HydrophobicContact CD1-CB 4.23Å; L185-R201 HydrophobicContact CD1-CG 4.22Å; L185-I234 HydrophobicContact CD1-CG2 4.47Å; L185-I234 HydrophobicContact CD2-CG2 3.9Å; L185-L397 HydrophobicContact CB-CD2 3.83Å; L185-L397 HydrophobicContact CD1-CD1 4.39Å; L185-L397 HydrophobicContact CD1-CD2 3.77Å; L185-L397 HydrophobicContact CG-CD2 4.36Å
186	Y	93.3	Very high	92.1	Very high	82 Å²	82	75 Å²	75	32%	0.322	38%	0.375	S	S	.	.	G	3₁₀ helix	trans	-78.7	-12.5	176.1	-70.1	-75.3	0	0	0	114.2	A183 F184 A198 L397 E398	A183-Y186 PolarHBondContact O-N 2.93Å; F184-Y186 PolarHBondContact O-N 3.01Å; Y186-A198 HydrophobicContact CD1-CB 3.86Å; Y186-A198 HydrophobicContact CE1-CB 3.92Å; Y186-A198 HydrophobicContact CG-CB 4.35Å; Y186-L397 HydrophobicContact CD2-CD2 4.32Å; Y186-L397 HydrophobicContact CE2-CD2 3.72Å; Y186-L397 HydrophobicContact CE2-CG 4.1Å; Y186-E398 WeakPolarHBondContact OH-CA 3.48Å; Y186-E398 PolarHBondContact OH-N 3.33Å
187	Y	93.7	Very high	92.3	Very high	159 Å²	159	69.2 Å²	69.2	62%	0.624	35%	0.35	S	S	*	.	S	Bend	trans	-106.6	-1.3	-177.1	-57.5	-79.9	0	0	0	113	A183 F184 L185	A183-Y187 WeakPolarHBondContact O-CD2 3.43Å; A183-Y187 WeakPolarHBondContact O-CE2 3.36Å; F184-Y187 PolarHBondContact O-N 3.44Å; L185-Y187 VanDerWaalsContact C-N 3.31Å
188	V	93.3	Very high	92.4	Very high	20 Å²	20	64.3 Å²	64.3	12%	0.121	33%	0.327	C	S	.	.			trans	-76.1	128.7	175.8	177.5	0	0	0	0	109.5	P190 D193 K195 D197	V188-P190 WeakPolarHBondContact O-CD 3.35Å; V188-D193 HydrophobicContact CG1-CB 3.8Å; V188-K195 HydrophobicContact CG1-CB 3.79Å; V188-K195 HydrophobicContact CG2-CB 4.25Å; V188-D197 HydrophobicContact CB-CB 4.09Å; V188-D197 HydrophobicContact CG1-CB 4.08Å
189	N	92.1	Very high	92.4	Very high	74 Å²	74	65.8 Å²	65.8	40%	0.396	35%	0.346	S	S	.	.			trans	-94.6	108.7	172.9	-173.4	-10	0	0	0	109.9	E191 V192 D193	N189-E191 PolarHBondContact O-N 3.03Å; N189-E191 PolarHBondContact OD1-N 3.36Å; N189-V192 PolarHBondContact O-N 3.13Å; N189-V192 VanDerWaalsContact O-N 3.11Å; N189-D193 PolarHBondContact N-OD2 3.32Å; N189-D193 WeakPolarHBondContact O-CB 3.46Å; N189-D193 PolarHBondContact O-N 2.95Å
190	P	91.4	Very high	92.6	Very high	69 Å²	69	64.3 Å²	64.3	45%	0.448	34%	0.339	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.5	-12.4	-173.8	28.8	-36.8	0	0	0	114.4	V188	V188-P190 WeakPolarHBondContact O-CD 3.35Å
191	E	90.5	Very high	92.9	Very high	179 Å²	179	63.9 Å²	63.9	84%	0.836	34%	0.336	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.7	-21.8	177	-61.9	-175.5	168.1	0	0	113.2	N189	N189-E191 PolarHBondContact O-N 3.03Å; N189-E191 PolarHBondContact OD1-N 3.36Å
192	V	90.9	Very high	93.2	Very high	112 Å²	112	59.6 Å²	59.6	68%	0.679	31%	0.314	S	S	*	.	T	Hydrogen-bonded Turn	trans	-122.3	-37.5	-172	-175.9	0	0	0	0	111.7	N189	N189-V192 PolarHBondContact O-N 3.13Å; N189-V192 VanDerWaalsContact O-N 3.11Å
193	D	90.2	Very high	93.4	Very high	56 Å²	56	64.4 Å²	64.4	30%	0.299	34%	0.336	S	S	.	.			trans	-93.3	124.9	-177.1	-66.4	-54.5	0	0	0	111.5	V188 N189 K195	V188-D193 HydrophobicContact CG1-CB 3.8Å; N189-D193 PolarHBondContact N-OD2 3.32Å; N189-D193 WeakPolarHBondContact O-CB 3.46Å; N189-D193 PolarHBondContact O-N 2.95Å; D193-K195 HydrophobicContact CB-CB 4.37Å; D193-K195 HydrophobicContact CB-CG 4.49Å; D193-K195 PolarHBondContact O-N 2.96Å
194	D	91.5	Very high	93.5	Very high	126 Å²	126	62.6 Å²	62.6	67%	0.674	32%	0.321	S	S	*	.			trans	-76.8	43.5	168.9	-70.2	-37.2	0	0	0	112.4	P241	D194-P241 VanDerWaalsContact C-CD 3.47Å; D194-P241 WeakPolarHBondContact O-CD 3.24Å
195	K	92.6	Very high	93.7	Very high	91 Å²	91	58.4 Å²	58.4	40%	0.396	30%	0.302	S	S	.	.	S	Bend	trans	-120.8	154.7	-178.3	-64.9	176.6	-176.5	169.8	0	110.7	V188 D193 D197 P241	V188-K195 HydrophobicContact CG1-CB 3.79Å; V188-K195 HydrophobicContact CG2-CB 4.25Å; D193-K195 HydrophobicContact CB-CB 4.37Å; D193-K195 HydrophobicContact CB-CG 4.49Å; D193-K195 PolarHBondContact O-N 2.96Å; K195-D197 PolarHBondContact O-N 2.81Å; K195-P241 WeakPolarHBondContact O-CG 3.35Å
196	V	95.3	Very high	93.7	Very high	5 Å²	5	61.3 Å²	61.3	3%	0.03	32%	0.316	C	S	.	.			trans	-64.4	127.2	171.3	176.5	0	0	0	0	109.6	L185 L200 R201 V239 M244	L185-V196 HydrophobicContact CD2-CB 4.44Å; L185-V196 HydrophobicContact CD2-CG1 4.34Å; L185-V196 WeakPolarHBondContact CD2-O 3.26Å; V196-L200 HydrophobicContact CG1-CD2 4.42Å; V196-L200 HydrophobicContact CG2-CD2 4.34Å; V196-R201 HydrophobicContact CG1-CB 4.1Å; V196-V239 HydrophobicContact CG2-CB 3.87Å; V196-V239 HydrophobicContact CG2-CG1 3.82Å; V196-V239 PolarHBondContact N-O 3.46Å; V196-M244 HydrophobicContact CG1-CG 4.39Å; V196-M244 HydrophobicContact CG1-SD 4Å; V196-M244 HydrophobicContact CG2-CB 4.15Å; V196-M244 HydrophobicContact CG2-CG 4.27Å; V196-M244 HydrophobicContact CG2-SD 3.96Å
197	D	95	Very high	93.6	Very high	15 Å²	15	61.7 Å²	61.7	8%	0.08	32%	0.323	C	S	.	.			trans	-98.6	166.3	171.1	63.1	-36.9	0	0	0	111.2	R50 V188 K195 A199 L200 R201	R50-D197 IonicContact CZ-OD1 2.7Å; R50-D197 IonicContact NH2-OD1 3.44Å; R50-D197 PolarHBondContact NH2-OD1 2.76Å; R50-D197 IonicContact NH2-OD2 2.75Å; R50-D197 PolarHBondContact NH2-OD2 3.43Å; V188-D197 HydrophobicContact CB-CB 4.09Å; V188-D197 HydrophobicContact CG1-CB 4.08Å; K195-D197 PolarHBondContact O-N 2.81Å; D197-A199 VanDerWaalsContact C-N 3.28Å; D197-A199 PolarHBondContact O-N 3.41Å; D197-L200 PolarHBondContact O-N 2.78Å; D197-L200 WeakPolarHBondContact OD1-CB 3.43Å; D197-L200 PolarHBondContact OD1-N 3.03Å; D197-R201 PolarHBondContact O-N 3.48Å; D197-R201 VanDerWaalsContact O-N 3.1Å
198	A	95.1	Very high	93.6	Very high	12 Å²	12	54.3 Å²	54.3	10%	0.099	30%	0.295	C	S	.	.	H	α-helix	trans	-56.9	-40.4	-178.3	0	0	0	0	0	112.9	L185 Y186 R201 D202 L397	L185-A198 HydrophobicContact CB-CB 4.18Å; L185-A198 PolarHBondContact O-N 2.88Å; Y186-A198 HydrophobicContact CD1-CB 3.86Å; Y186-A198 HydrophobicContact CE1-CB 3.92Å; Y186-A198 HydrophobicContact CG-CB 4.35Å; A198-R201 PolarHBondContact O-N 3.02Å; A198-D202 PolarHBondContact O-N 2.83Å; A198-L397 HydrophobicContact CB-CD2 3.74Å
199	A	94.4	Very high	93.6	Very high	62 Å²	62	54.9 Å²	54.9	51%	0.512	30%	0.295	S	S	.	.	H	α-helix	trans	-66.3	-41.4	-179.1	0	0	0	0	0	112.5	D197 D202 E203	D197-A199 VanDerWaalsContact C-N 3.28Å; D197-A199 PolarHBondContact O-N 3.41Å; A199-D202 PolarHBondContact O-N 3.05Å; A199-E203 WeakPolarHBondContact O-CB 3.2Å; A199-E203 PolarHBondContact O-N 3.17Å
200	L	95.4	Very high	93.5	Very high	22 Å²	22	57.2 Å²	57.2	12%	0.115	30%	0.302	C	S	.	.	H	α-helix	trans	-68	-36.6	177	-178.2	66.4	0	0	0	112	V196 D197 A204 P241 M244	V196-L200 HydrophobicContact CG1-CD2 4.42Å; V196-L200 HydrophobicContact CG2-CD2 4.34Å; D197-L200 PolarHBondContact O-N 2.78Å; D197-L200 WeakPolarHBondContact OD1-CB 3.43Å; D197-L200 PolarHBondContact OD1-N 3.03Å; L200-A204 WeakPolarHBondContact O-CB 3.39Å; L200-A204 PolarHBondContact O-N 2.8Å; L200-P241 HydrophobicContact CD2-CB 3.58Å; L200-P241 HydrophobicContact CD2-CG 4.23Å; L200-M244 HydrophobicContact CD2-CB 4.07Å; L200-M244 HydrophobicContact CD2-CG 4.32Å; L200-M244 HydrophobicContact CG-CB 4.26Å; L200-M244 HydrophobicContact CG-CG 4.08Å
201	R	96.6	Very high	93.4	Very high	0 Å²	0	54.1 Å²	54.1	0%	0	28%	0.281	C	S	.	.	H	α-helix	trans	-60.9	-48.7	173.3	179.2	-86.2	-177.6	-159.2	-9	110.6	L185 V196 D197 A198 E203 A204 V205 V227 D231 I234 M244 L394 Y400	L185-R201 HydrophobicContact CD1-CB 4.23Å; L185-R201 HydrophobicContact CD1-CG 4.22Å; V196-R201 HydrophobicContact CG1-CB 4.1Å; D197-R201 PolarHBondContact O-N 3.48Å; D197-R201 VanDerWaalsContact O-N 3.1Å; A198-R201 PolarHBondContact O-N 3.02Å; R201-E203 PolarHBondContact O-N 3.42Å; R201-A204 PolarHBondContact O-N 2.67Å; R201-V205 WeakPolarHBondContact O-CG2 3.44Å; R201-V205 PolarHBondContact O-N 2.8Å; R201-V227 VanDerWaalsContact NH2-CG1 3.29Å; R201-D231 IonicContact CZ-OD1 3.58Å; R201-D231 IonicContact CZ-OD2 2.8Å; R201-D231 IonicContact NE-OD1 3.71Å; R201-D231 PolarHBondContact NE-OD1 3.29Å; R201-D231 IonicContact NE-OD2 2.69Å; R201-D231 IonicContact NH2-OD1 3.2Å; R201-D231 PolarHBondContact NH2-OD1 3.18Å; R201-D231 IonicContact NH2-OD2 3.75Å; R201-D231 PolarHBondContact NH2-OD2 2.99Å; R201-I234 HydrophobicContact CG-CD1 4.35Å; R201-M244 HydrophobicContact CG-CE 4.43Å; R201-L394 PolarHBondContact NH1-O 3.24Å; R201-L394 PolarHBondContact NH2-O 2.58Å; R201-Y400 VanDerWaalsContact NH2-CE2 3.34Å
202	D	95.8	Very high	93.4	Very high	25 Å²	25	45.7 Å²	45.7	13%	0.134	24%	0.242	C	C	.	.	H	α-helix	trans	-64.8	-40.1	-179.4	-75.7	-1.1	0	0	0	111.9	A198 A199 V205 H206 C395 S396 L397	A198-D202 PolarHBondContact O-N 2.83Å; A199-D202 PolarHBondContact O-N 3.05Å; D202-V205 PolarHBondContact O-N 3.31Å; D202-H206 VanDerWaalsContact O-CB 3.23Å; D202-H206 WeakPolarHBondContact O-CB 3.4Å; D202-H206 PolarHBondContact O-N 2.8Å; D202-C395 WeakPolarHBondContact CA-O 3.21Å; D202-C395 WeakPolarHBondContact CB-O 3.24Å; D202-C395 VanDerWaalsContact CG-O 3.25Å; D202-S396 WeakPolarHBondContact OD2-CA 3.37Å; D202-L397 VanDerWaalsContact CG-N 3.34Å; D202-L397 WeakPolarHBondContact OD1-CB 3.46Å; D202-L397 PolarHBondContact OD1-N 3.02Å; D202-L397 PolarHBondContact OD2-N 3.45Å; D202-L397 VanDerWaalsContact OD2-N 3.17Å
203	E	94.8	Very high	93.2	Very high	105 Å²	105	42.8 Å²	42.8	49%	0.491	22%	0.223	S	C	.	.	H	α-helix	trans	-60.5	-45.6	173.3	-175.5	179.8	172.6	0	0	111.8	A199 R201 H206 N207	A199-E203 WeakPolarHBondContact O-CB 3.2Å; A199-E203 PolarHBondContact O-N 3.17Å; R201-E203 PolarHBondContact O-N 3.42Å; E203-H206 PolarHBondContact O-N 3.09Å; E203-N207 WeakPolarHBondContact O-CB 3.5Å; E203-N207 VanDerWaalsContact O-CG 3.27Å; E203-N207 PolarHBondContact O-N 3.36Å; E203-N207 PolarHBondContact O-ND2 3.43Å
204	A	95.4	Very high	92.8	Very high	10 Å²	10	42.9 Å²	42.9	8%	0.083	23%	0.228	C	C	.	.	H	α-helix	trans	-63.7	-43.9	179.1	0	0	0	0	0	112.2	L200 R201 N207 L208 M244 A248	L200-A204 WeakPolarHBondContact O-CB 3.39Å; L200-A204 PolarHBondContact O-N 2.8Å; R201-A204 PolarHBondContact O-N 2.67Å; A204-N207 PolarHBondContact O-N 3.35Å; A204-L208 WeakPolarHBondContact O-CB 3.46Å; A204-L208 PolarHBondContact O-N 3.46Å; A204-M244 HydrophobicContact CB-CE 3.57Å; A204-M244 HydrophobicContact CB-CG 3.79Å; A204-A248 HydrophobicContact CB-CB 4.36Å
205	V	95.9	Very high	92	Very high	0 Å²	0	41.8 Å²	41.8	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-68.1	-37.5	177	176.8	0	0	0	0	111.3	R201 D202 L208 R209 F223 V227 I230	R201-V205 WeakPolarHBondContact O-CG2 3.44Å; R201-V205 PolarHBondContact O-N 2.8Å; D202-V205 PolarHBondContact O-N 3.31Å; V205-L208 WeakPolarHBondContact O-CB 3.4Å; V205-L208 PolarHBondContact O-N 3.38Å; V205-R209 PolarHBondContact O-N 2.79Å; V205-F223 HydrophobicContact CG1-CE2 4.44Å; V205-F223 HydrophobicContact CG1-CZ 3.83Å; V205-V227 HydrophobicContact CG1-CG1 4.34Å; V205-V227 HydrophobicContact CG1-CG2 3.63Å; V205-V227 HydrophobicContact CG2-CG1 4.47Å; V205-I230 HydrophobicContact CG2-CD1 4.33Å
206	H	93.7	Very high	91.1	Very high	63 Å²	63	39.5 Å²	39.5	29%	0.292	21%	0.207	S	C	.	.	H	α-helix	trans	-62.9	-45.1	174.9	-176	82.5	0	0	0	112	D202 E203 L208 R209 F210 Y448	D202-H206 VanDerWaalsContact O-CB 3.23Å; D202-H206 WeakPolarHBondContact O-CB 3.4Å; D202-H206 PolarHBondContact O-N 2.8Å; E203-H206 PolarHBondContact O-N 3.09Å; H206-L208 VanDerWaalsContact C-N 3.27Å; H206-L208 PolarHBondContact O-N 2.93Å; H206-R209 WeakPolarHBondContact O-CB 3.29Å; H206-R209 PolarHBondContact O-N 3.49Å; H206-F210 PolarHBondContact O-N 3.08Å; H206-Y448 AromaticContact CE1-CD1 3.55Å; H206-Y448 AromaticContact CE1-CE1 3.9Å; H206-Y448 AromaticContact ND1-CD1 3.48Å; H206-Y448 WeakPolarHBondContact ND1-CD1 3.36Å; H206-Y448 AromaticContact ND1-CE1 3.45Å; H206-Y448 WeakPolarHBondContact ND1-CE1 3.4Å
207	N	92.8	Very high	90	Very high	90 Å²	90	45.1 Å²	45.1	48%	0.481	24%	0.237	S	C	.	.	H	α-helix	trans	-61.6	-38.1	174.3	-72.6	-25.4	0	0	0	111.5	E203 A204 F210 L211	E203-N207 WeakPolarHBondContact O-CB 3.5Å; E203-N207 VanDerWaalsContact O-CG 3.27Å; E203-N207 PolarHBondContact O-N 3.36Å; E203-N207 PolarHBondContact O-ND2 3.43Å; A204-N207 PolarHBondContact O-N 3.35Å; N207-F210 WeakPolarHBondContact O-CB 3.24Å; N207-F210 PolarHBondContact O-N 3.14Å; N207-L211 PolarHBondContact O-N 2.89Å
208	L	93.1	Very high	89.3	Confident	5 Å²	5	46.2 Å²	46.2	3%	0.026	24%	0.243	C	C	.	.	H	α-helix	trans	-65.3	-39.5	174.7	-174.4	65.1	0	0	0	112.2	A204 V205 H206 F210 L211 H212 F223 A226 I230 Y252	A204-L208 WeakPolarHBondContact O-CB 3.46Å; A204-L208 PolarHBondContact O-N 3.46Å; V205-L208 WeakPolarHBondContact O-CB 3.4Å; V205-L208 PolarHBondContact O-N 3.38Å; H206-L208 VanDerWaalsContact C-N 3.27Å; H206-L208 PolarHBondContact O-N 2.93Å; L208-F210 VanDerWaalsContact C-N 3.33Å; L208-F210 PolarHBondContact O-N 2.97Å; L208-L211 HydrophobicContact CD1-CD2 3.98Å; L208-L211 WeakPolarHBondContact O-CB 3.44Å; L208-L211 PolarHBondContact O-N 2.88Å; L208-H212 WeakPolarHBondContact O-CB 3.31Å; L208-H212 PolarHBondContact O-N 3.08Å; L208-F223 HydrophobicContact CD2-CE2 4.49Å; L208-F223 HydrophobicContact CG-CE2 4.34Å; L208-A226 HydrophobicContact CD2-CB 4.25Å; L208-I230 HydrophobicContact CD2-CD1 3.74Å; L208-Y252 HydrophobicContact CD1-CD1 4.36Å; L208-Y252 HydrophobicContact CD1-CD2 3.95Å; L208-Y252 HydrophobicContact CD1-CG 3.73Å; L208-Y252 HydrophobicContact CD2-CD2 4.45Å; L208-Y252 HydrophobicContact CG-CD2 4.38Å
209	R	92.4	Very high	89	Confident	31 Å²	31	48.1 Å²	48.1	12%	0.117	26%	0.256	C	S	.	.	H	α-helix	trans	-63.4	-41.1	174.4	-176.9	178.6	165.8	-91.6	-4.2	111.4	V205 H206 L211 H212 N213 F223 E391 I392 C395	V205-R209 PolarHBondContact O-N 2.79Å; H206-R209 WeakPolarHBondContact O-CB 3.29Å; H206-R209 PolarHBondContact O-N 3.49Å; R209-L211 VanDerWaalsContact C-N 3.33Å; R209-H212 PolarHBondContact O-N 2.85Å; R209-N213 PolarHBondContact O-N 3.32Å; R209-F223 HydrophobicContact CB-CD2 4.48Å; R209-F223 HydrophobicContact CB-CE2 3.6Å; R209-F223 HydrophobicContact CB-CZ 3.74Å; R209-F223 HydrophobicContact CG-CE2 4.28Å; R209-F223 HydrophobicContact CG-CZ 4.24Å; R209-E391 HydrophobicContact CG-CB 4.45Å; R209-E391 IonicContact NE-OE2 3.59Å; R209-I392 VanDerWaalsContact CZ-CG1 3.45Å; R209-I392 VanDerWaalsContact NH2-CG1 3.34Å; R209-C395 WeakPolarHBondContact CD-SG 3.15Å
210	F	90.3	Very high	88.9	Confident	124 Å²	124	46.2 Å²	46.2	54%	0.544	24%	0.238	S	C	.	.	H	α-helix	trans	-59.9	-44.7	173.9	176.7	-95.6	0	0	0	111.2	H206 N207 L208 S214 F215	H206-F210 PolarHBondContact O-N 3.08Å; N207-F210 WeakPolarHBondContact O-CB 3.24Å; N207-F210 PolarHBondContact O-N 3.14Å; L208-F210 VanDerWaalsContact C-N 3.33Å; L208-F210 PolarHBondContact O-N 2.97Å; F210-S214 WeakPolarHBondContact CE2-OG 3.18Å; F210-S214 WeakPolarHBondContact O-CB 3.39Å; F210-S214 PolarHBondContact O-N 2.75Å; F210-S214 PolarHBondContact O-OG 3.46Å; F210-F215 HydrophobicContact CE1-CE2 4Å
211	L	89.7	Confident	88.7	Confident	4 Å²	4	48 Å²	48	2%	0.021	25%	0.245	C	C	.	.	H	α-helix	trans	-57.7	-51.7	174.3	178.6	76.7	0	0	0	111.5	N207 L208 R209 N213 S214 F215 F216 Y252 I277 T278	N207-L211 PolarHBondContact O-N 2.89Å; L208-L211 HydrophobicContact CD1-CD2 3.98Å; L208-L211 WeakPolarHBondContact O-CB 3.44Å; L208-L211 PolarHBondContact O-N 2.88Å; R209-L211 VanDerWaalsContact C-N 3.33Å; L211-N213 PolarHBondContact O-N 3.46Å; L211-S214 PolarHBondContact O-N 2.86Å; L211-F215 HydrophobicContact CD1-CD2 3.82Å; L211-F215 HydrophobicContact CD1-CE2 4.42Å; L211-F215 HydrophobicContact CD1-CG 4.37Å; L211-F215 PolarHBondContact O-N 3.25Å; L211-F215 VanDerWaalsContact O-N 3.08Å; L211-F216 HydrophobicContact CD1-CD2 4.46Å; L211-F216 HydrophobicContact CD1-CE2 3.82Å; L211-F216 HydrophobicContact CD2-CD2 4.49Å; L211-F216 HydrophobicContact CD2-CE2 4.02Å; L211-F216 HydrophobicContact CG-CD2 4.09Å; L211-F216 HydrophobicContact CG-CE2 3.81Å; L211-Y252 HydrophobicContact CD2-CD1 4.11Å; L211-Y252 HydrophobicContact CD2-CE1 4.21Å; L211-I277 HydrophobicContact CD1-CB 3.84Å; L211-I277 HydrophobicContact CD1-CD1 4.34Å; L211-I277 HydrophobicContact CD1-CG2 3.31Å; L211-T278 HydrophobicContact CD1-CG2 4.1Å; L211-T278 HydrophobicContact CD2-CG2 3.55Å; L211-T278 HydrophobicContact CG-CG2 4.34Å
212	H	89.7	Confident	88.5	Confident	1 Å²	1	48.1 Å²	48.1	1%	0.005	25%	0.246	C	C	.	.	I	π-helix	trans	-53.7	-51	-178.7	176.9	-97.3	0	0	0	111.9	L208 R209 F216 N217 L218 S219 F223 Y252 E391	L208-H212 WeakPolarHBondContact O-CB 3.31Å; L208-H212 PolarHBondContact O-N 3.08Å; R209-H212 PolarHBondContact O-N 2.85Å; H212-F216 PolarHBondContact O-N 2.9Å; H212-N217 PolarHBondContact O-N 3.28Å; H212-L218 PolarHBondContact CE1-O 2.83Å; H212-L218 PolarHBondContact NE2-O 3.09Å; H212-S219 PolarHBondContact NE2-O 2.92Å; H212-F223 HydrophobicContact CB-CD2 4.23Å; H212-Y252 HydrophobicContact CB-CE2 4.37Å; H212-Y252 AromaticContact CD2-CE2 3.76Å; H212-Y252 AromaticContact CD2-CZ 4Å; H212-Y252 PolarHBondContact CD2-OH 3.03Å; H212-E391 IonicContact CE1-OE1 3.91Å; H212-E391 IonicContact ND1-OE1 3.84Å
213	N	87.4	Confident	88.5	Confident	52 Å²	52	47 Å²	47	28%	0.278	24%	0.24	S	C	.	.	I	π-helix	trans	-83	-19.9	-174.1	-70	-17.3	0	0	0	114.1	R209 L211 N217 E391	R209-N213 PolarHBondContact O-N 3.32Å; L211-N213 PolarHBondContact O-N 3.46Å; N213-N217 PolarHBondContact O-OD1 3.46Å; N213-E391 PolarHBondContact ND2-OE2 3.04Å; N213-E391 PolarHBondContact OD1-OE2 3.08Å
214	S	82.2	Confident	88.5	Confident	58 Å²	58	42 Å²	42	41%	0.406	22%	0.217	S	C	.	.	I	π-helix	trans	-93.9	-30.7	-177.4	-54	0	0	0	0	113	F210 L211	F210-S214 WeakPolarHBondContact CE2-OG 3.18Å; F210-S214 WeakPolarHBondContact O-CB 3.39Å; F210-S214 PolarHBondContact O-N 2.75Å; F210-S214 PolarHBondContact O-OG 3.46Å; L211-S214 PolarHBondContact O-N 2.86Å
215	F	75.3	Confident	88.5	Confident	102 Å²	102	42.3 Å²	42.3	45%	0.447	22%	0.216	S	C	.	.	I	π-helix	trans	-119.1	-41.8	-168.2	-61.7	-85.4	0	0	0	114	F210 L211 I277	F210-F215 HydrophobicContact CE1-CE2 4Å; L211-F215 HydrophobicContact CD1-CD2 3.82Å; L211-F215 HydrophobicContact CD1-CE2 4.42Å; L211-F215 HydrophobicContact CD1-CG 4.37Å; L211-F215 PolarHBondContact O-N 3.25Å; L211-F215 VanDerWaalsContact O-N 3.08Å; F215-I277 HydrophobicContact CB-CD1 4.3Å; F215-I277 HydrophobicContact CD1-CD1 3.64Å; F215-I277 HydrophobicContact CD1-CG1 4.37Å; F215-I277 HydrophobicContact CD1-CG2 4.41Å; F215-I277 HydrophobicContact CD2-CD1 4.46Å; F215-I277 HydrophobicContact CD2-CG2 3.78Å; F215-I277 HydrophobicContact CE1-CD1 4.03Å; F215-I277 HydrophobicContact CE1-CG1 4.26Å; F215-I277 HydrophobicContact CE1-CG2 4.08Å; F215-I277 HydrophobicContact CE2-CG2 3.4Å; F215-I277 HydrophobicContact CG-CD1 3.88Å; F215-I277 HydrophobicContact CG-CG2 4.26Å; F215-I277 HydrophobicContact CZ-CG2 3.56Å
216	F	72.6	Confident	88.5	Confident	44 Å²	44	42.3 Å²	42.3	19%	0.193	22%	0.216	C	C	.	.	I	π-helix	trans	-107.1	-26.8	-170.7	-58	-64.2	0	0	0	113.9	L211 H212 L218 Y252 P269 I274	L211-F216 HydrophobicContact CD1-CD2 4.46Å; L211-F216 HydrophobicContact CD1-CE2 3.82Å; L211-F216 HydrophobicContact CD2-CD2 4.49Å; L211-F216 HydrophobicContact CD2-CE2 4.02Å; L211-F216 HydrophobicContact CG-CD2 4.09Å; L211-F216 HydrophobicContact CG-CE2 3.81Å; H212-F216 PolarHBondContact O-N 2.9Å; F216-L218 HydrophobicContact CB-CD1 4.21Å; F216-L218 HydrophobicContact CB-CG 3.87Å; F216-L218 PolarHBondContact O-N 3.46Å; F216-L218 VanDerWaalsContact O-N 3.08Å; F216-Y252 AromaticContact CD2-CE1 3.62Å; F216-Y252 HydrophobicContact CD2-CE1 3.62Å; F216-Y252 AromaticContact CE2-CE1 3.98Å; F216-Y252 HydrophobicContact CE2-CE1 3.98Å; F216-Y252 HydrophobicContact CG-CE1 4.41Å; F216-P269 HydrophobicContact CD1-CB 4.05Å; F216-P269 HydrophobicContact CD1-CG 3.58Å; F216-P269 HydrophobicContact CD2-CG 4.42Å; F216-P269 HydrophobicContact CE1-CB 3.38Å; F216-P269 HydrophobicContact CE1-CG 3.46Å; F216-P269 VanDerWaalsContact CE1-CG 3.46Å; F216-P269 HydrophobicContact CE2-CB 4.33Å; F216-P269 HydrophobicContact CE2-CG 4.3Å; F216-P269 HydrophobicContact CG-CG 4.07Å; F216-P269 HydrophobicContact CZ-CB 3.55Å; F216-P269 HydrophobicContact CZ-CG 3.85Å; F216-I274 HydrophobicContact CE2-CG1 4.07Å; F216-I274 HydrophobicContact CZ-CD1 4.41Å; F216-I274 HydrophobicContact CZ-CG1 3.78Å
217	N	73	Confident	88.7	Confident	122 Å²	122	39.3 Å²	39.3	65%	0.652	20%	0.202	S	C	*	.			trans	45.2	41.3	179.7	-75.1	-40	0	0	0	112.8	H212 N213	H212-N217 PolarHBondContact O-N 3.28Å; N213-N217 PolarHBondContact O-OD1 3.46Å
218	L	80.1	Confident	88.8	Confident	38 Å²	38	35.4 Å²	35.4	20%	0.199	18%	0.181	C	C	.	.			trans	-74.7	179.3	178.3	-63.5	-179.9	0	0	0	111.1	H212 F216 T222 Y252 C256 V266	H212-L218 PolarHBondContact CE1-O 2.83Å; H212-L218 PolarHBondContact NE2-O 3.09Å; F216-L218 HydrophobicContact CB-CD1 4.21Å; F216-L218 HydrophobicContact CB-CG 3.87Å; F216-L218 PolarHBondContact O-N 3.46Å; F216-L218 VanDerWaalsContact O-N 3.08Å; L218-T222 HydrophobicContact CB-CG2 4.39Å; L218-T222 HydrophobicContact CD1-CG2 3.9Å; L218-Y252 WeakPolarHBondContact CD1-OH 3.41Å; L218-C256 VanDerWaalsContact CD1-SG 3.5Å; L218-V266 HydrophobicContact CD2-CG1 3.76Å
219	S	88.3	Confident	89.1	Confident	53 Å²	53	35.1 Å²	35.1	37%	0.371	18%	0.18	S	C	.	.			trans	-64.5	144.1	175.8	64.2	0	0	0	0	111.1	H212 E221 T222	H212-S219 PolarHBondContact NE2-O 2.92Å; S219-E221 PolarHBondContact O-N 2.85Å; S219-E221 VanDerWaalsContact O-N 3.11Å; S219-T222 VanDerWaalsContact O-CB 3.26Å; S219-T222 WeakPolarHBondContact O-CB 2.76Å; S219-T222 PolarHBondContact O-N 3.16Å; S219-T222 PolarHBondContact O-OG1 3.15Å; S219-T222 PolarHBondContact OG-N 3.26Å; S219-T222 PolarHBondContact OG-OG1 2.74Å
220	T	91.6	Very high	89.3	Confident	22 Å²	22	33.7 Å²	33.7	14%	0.135	18%	0.175	C	C	.	.	H	α-helix	trans	-54.4	-30.7	171.5	-61.2	0	0	0	0	112.3	T222 F223 C224 F308 M390 E391	T220-T222 VanDerWaalsContact C-N 3.29Å; T220-T222 PolarHBondContact O-N 3.48Å; T220-F223 PolarHBondContact O-N 2.85Å; T220-C224 PolarHBondContact O-N 3.27Å; T220-C224 PolarHBondContact O-SG 3.13Å; T220-F308 HydrophobicContact CG2-CD2 3.89Å; T220-F308 HydrophobicContact CG2-CE2 3.82Å; T220-M390 HydrophobicContact CG2-CB 4.46Å; T220-E391 WeakPolarHBondContact CB-OE1 3.5Å; T220-E391 HydrophobicContact CG2-CG 3.68Å; T220-E391 PolarHBondContact OG1-OE1 3.14Å
221	E	92.6	Very high	89.6	Confident	59 Å²	59	27.8 Å²	27.8	28%	0.276	15%	0.149	S	C	.	.	H	α-helix	trans	-53.9	-44.8	172.4	-169.5	-169.5	160.2	0	0	112.2	S219 F223 C224 K225 F308	S219-E221 PolarHBondContact O-N 2.85Å; S219-E221 VanDerWaalsContact O-N 3.11Å; E221-F223 VanDerWaalsContact C-N 3.33Å; E221-F223 PolarHBondContact O-N 3.44Å; E221-C224 PolarHBondContact O-N 2.89Å; E221-K225 HydrophobicContact CG-CD 4.19Å; E221-K225 WeakPolarHBondContact O-CB 3.44Å; E221-K225 WeakPolarHBondContact O-CG 3.25Å; E221-K225 PolarHBondContact O-N 2.64Å; E221-K225 WeakPolarHBondContact OE1-CE 3.43Å; E221-K225 IonicContact OE1-NZ 3.48Å; E221-K225 PolarHBondContact OE1-NZ 3.02Å; E221-F308 HydrophobicContact CB-CD1 3.81Å; E221-F308 HydrophobicContact CB-CE1 3.47Å; E221-F308 VanDerWaalsContact CB-CE1 3.47Å; E221-F308 HydrophobicContact CB-CZ 4.07Å; E221-F308 HydrophobicContact CG-CD1 3.83Å; E221-F308 HydrophobicContact CG-CE1 3.81Å
222	T	92.5	Very high	89.9	Confident	3 Å²	3	28.5 Å²	28.5	2%	0.018	15%	0.151	C	C	.	.	H	α-helix	trans	-60.3	-45.3	179.9	-54.5	0	0	0	0	110.3	L218 S219 T220 A226 Y252 V255	L218-T222 HydrophobicContact CB-CG2 4.39Å; L218-T222 HydrophobicContact CD1-CG2 3.9Å; S219-T222 VanDerWaalsContact O-CB 3.26Å; S219-T222 WeakPolarHBondContact O-CB 2.76Å; S219-T222 PolarHBondContact O-N 3.16Å; S219-T222 PolarHBondContact O-OG1 3.15Å; S219-T222 PolarHBondContact OG-N 3.26Å; S219-T222 PolarHBondContact OG-OG1 2.74Å; T220-T222 VanDerWaalsContact C-N 3.29Å; T220-T222 PolarHBondContact O-N 3.48Å; T222-A226 WeakPolarHBondContact O-CB 3.45Å; T222-A226 PolarHBondContact O-N 2.75Å; T222-Y252 HydrophobicContact CG2-CE2 4.15Å; T222-V255 HydrophobicContact CG2-CB 4.38Å; T222-V255 HydrophobicContact CG2-CG1 3.72Å
223	F	94.4	Very high	90.3	Very high	0 Å²	0	28.6 Å²	28.6	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-63.2	-46.6	175.4	178.7	-98.3	0	0	0	112.1	V205 L208 R209 H212 T220 E221 K225 A226 V227 E391 L394	V205-F223 HydrophobicContact CG1-CE2 4.44Å; V205-F223 HydrophobicContact CG1-CZ 3.83Å; L208-F223 HydrophobicContact CD2-CE2 4.49Å; L208-F223 HydrophobicContact CG-CE2 4.34Å; R209-F223 HydrophobicContact CB-CD2 4.48Å; R209-F223 HydrophobicContact CB-CE2 3.6Å; R209-F223 HydrophobicContact CB-CZ 3.74Å; R209-F223 HydrophobicContact CG-CE2 4.28Å; R209-F223 HydrophobicContact CG-CZ 4.24Å; H212-F223 HydrophobicContact CB-CD2 4.23Å; T220-F223 PolarHBondContact O-N 2.85Å; E221-F223 VanDerWaalsContact C-N 3.33Å; E221-F223 PolarHBondContact O-N 3.44Å; F223-K225 PolarHBondContact O-N 3.29Å; F223-A226 PolarHBondContact O-N 3.1Å; F223-V227 HydrophobicContact CD1-CG2 4.24Å; F223-V227 HydrophobicContact CD2-CG2 4.48Å; F223-V227 HydrophobicContact CE1-CG2 3.75Å; F223-V227 HydrophobicContact CE2-CG2 4Å; F223-V227 HydrophobicContact CZ-CG2 3.63Å; F223-V227 WeakPolarHBondContact O-CG2 3.36Å; F223-V227 PolarHBondContact O-N 3.3Å; F223-E391 HydrophobicContact CB-CG 4.49Å; F223-E391 HydrophobicContact CD1-CB 3.96Å; F223-E391 HydrophobicContact CD1-CG 3.67Å; F223-E391 HydrophobicContact CE1-CB 3.96Å; F223-E391 HydrophobicContact CE1-CG 4.2Å; F223-E391 WeakPolarHBondContact CE1-O 3.29Å; F223-E391 HydrophobicContact CG-CG 4.22Å; F223-L394 HydrophobicContact CE1-CB 4.17Å
224	C	95.8	Very high	90.7	Very high	2 Å²	2	26.5 Å²	26.5	1%	0.014	14%	0.14	C	C	.	.	H	α-helix	trans	-62.2	-43.4	-178.1	-64.3	0	0	0	0	112.1	T220 E221 V227 N228 F308 M390 L394	T220-C224 PolarHBondContact O-N 3.27Å; T220-C224 PolarHBondContact O-SG 3.13Å; E221-C224 PolarHBondContact O-N 2.89Å; C224-V227 PolarHBondContact O-N 2.95Å; C224-N228 PolarHBondContact O-N 3.21Å; C224-F308 HydrophobicContact CB-CB 3.83Å; C224-F308 HydrophobicContact CB-CG 4.46Å; C224-M390 VanDerWaalsContact SG-CG 3.52Å; C224-L394 HydrophobicContact CB-CD1 3.99Å; C224-L394 VanDerWaalsContact SG-CD1 3.59Å
225	K	95.5	Very high	91.3	Very high	16 Å²	16	26.7 Å²	26.7	7%	0.07	14%	0.139	C	C	.	.	H	α-helix	trans	-62.7	-44.1	174.1	-74.5	-179.4	176.3	178.3	0	111.1	E221 F223 V227 N228 L229 V255 D303 N306	E221-K225 HydrophobicContact CG-CD 4.19Å; E221-K225 WeakPolarHBondContact O-CB 3.44Å; E221-K225 WeakPolarHBondContact O-CG 3.25Å; E221-K225 PolarHBondContact O-N 2.64Å; E221-K225 WeakPolarHBondContact OE1-CE 3.43Å; E221-K225 IonicContact OE1-NZ 3.48Å; E221-K225 PolarHBondContact OE1-NZ 3.02Å; F223-K225 PolarHBondContact O-N 3.29Å; K225-V227 VanDerWaalsContact C-N 3.33Å; K225-V227 PolarHBondContact O-N 3.01Å; K225-N228 WeakPolarHBondContact O-CB 3.46Å; K225-N228 PolarHBondContact O-N 3.24Å; K225-N228 VanDerWaalsContact O-N 3.15Å; K225-L229 WeakPolarHBondContact O-CG 3.33Å; K225-L229 PolarHBondContact O-N 3.29Å; K225-V255 HydrophobicContact CB-CG1 3.74Å; K225-V255 HydrophobicContact CB-CG2 3.93Å; K225-V255 HydrophobicContact CD-CG1 4.46Å; K225-D303 WeakPolarHBondContact CE-OD1 3.36Å; K225-D303 IonicContact NZ-OD1 3.29Å; K225-D303 PolarHBondContact NZ-OD1 3Å; K225-N306 WeakPolarHBondContact CG-ND2 3.37Å
226	A	96.2	Very high	92.2	Very high	0 Å²	0	27.3 Å²	27.3	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-60.3	-42.4	178.6	0	0	0	0	0	112	L208 T222 F223 L229 I230 Y252 V255	L208-A226 HydrophobicContact CD2-CB 4.25Å; T222-A226 WeakPolarHBondContact O-CB 3.45Å; T222-A226 PolarHBondContact O-N 2.75Å; F223-A226 PolarHBondContact O-N 3.1Å; A226-L229 PolarHBondContact O-N 2.88Å; A226-I230 VanDerWaalsContact O-CG1 3.27Å; A226-I230 WeakPolarHBondContact O-CG1 3.43Å; A226-I230 PolarHBondContact O-N 3.31Å; A226-Y252 HydrophobicContact CB-CD2 4.02Å; A226-V255 HydrophobicContact CB-CG2 4.25Å
227	V	97	Very high	93.3	Very high	0 Å²	0	27 Å²	27	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-64.4	-42.4	175.5	178.3	0	0	0	0	111.5	R201 V205 F223 C224 K225 L229 I230 D231 L394	R201-V227 VanDerWaalsContact NH2-CG1 3.29Å; V205-V227 HydrophobicContact CG1-CG1 4.34Å; V205-V227 HydrophobicContact CG1-CG2 3.63Å; V205-V227 HydrophobicContact CG2-CG1 4.47Å; F223-V227 HydrophobicContact CD1-CG2 4.24Å; F223-V227 HydrophobicContact CD2-CG2 4.48Å; F223-V227 HydrophobicContact CE1-CG2 3.75Å; F223-V227 HydrophobicContact CE2-CG2 4Å; F223-V227 HydrophobicContact CZ-CG2 3.63Å; F223-V227 WeakPolarHBondContact O-CG2 3.36Å; F223-V227 PolarHBondContact O-N 3.3Å; C224-V227 PolarHBondContact O-N 2.95Å; K225-V227 VanDerWaalsContact C-N 3.33Å; K225-V227 PolarHBondContact O-N 3.01Å; V227-L229 VanDerWaalsContact C-N 3.31Å; V227-L229 PolarHBondContact O-N 3.49Å; V227-I230 WeakPolarHBondContact O-CB 3.47Å; V227-I230 PolarHBondContact O-N 3.09Å; V227-D231 WeakPolarHBondContact CG1-OD2 3.27Å; V227-D231 PolarHBondContact O-N 3.34Å; V227-L394 HydrophobicContact CG1-CB 4.29Å
228	N	96.3	Very high	94.3	Very high	7 Å²	7	28.6 Å²	28.6	4%	0.037	14%	0.144	C	C	.	.	H	α-helix	trans	-58.8	-42.1	175.5	-176.5	-98.6	0	0	0	112.1	Y178 C224 K225 D231 R232 N306	Y178-N228 PolarHBondContact O-ND2 2.91Å; C224-N228 PolarHBondContact O-N 3.21Å; K225-N228 WeakPolarHBondContact O-CB 3.46Å; K225-N228 PolarHBondContact O-N 3.24Å; K225-N228 VanDerWaalsContact O-N 3.15Å; N228-D231 PolarHBondContact O-N 2.73Å; N228-R232 WeakPolarHBondContact O-CB 3.32Å; N228-R232 VanDerWaalsContact O-CG 3.29Å; N228-R232 WeakPolarHBondContact O-CG 3.34Å; N228-R232 PolarHBondContact O-N 3.41Å; N228-R232 WeakPolarHBondContact OD1-CD 3.27Å; N228-N306 HydrophobicContact CB-CB 4.37Å
229	L	97.4	Very high	95	Very high	0 Å²	0	27.4 Å²	27.4	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-64.4	-44	175.9	-64.1	-175.3	0	0	0	112.6	K225 A226 V227 D231 R232 F233 A254 V255 L294 L298 L302	K225-L229 WeakPolarHBondContact O-CG 3.33Å; K225-L229 PolarHBondContact O-N 3.29Å; A226-L229 PolarHBondContact O-N 2.88Å; V227-L229 VanDerWaalsContact C-N 3.31Å; V227-L229 PolarHBondContact O-N 3.49Å; L229-D231 VanDerWaalsContact C-N 3.3Å; L229-D231 PolarHBondContact O-N 3.21Å; L229-R232 PolarHBondContact O-N 2.85Å; L229-F233 WeakPolarHBondContact O-CB 3.31Å; L229-F233 PolarHBondContact O-N 3.28Å; L229-A254 HydrophobicContact CD1-CB 4.38Å; L229-V255 HydrophobicContact CD1-CG2 3.44Å; L229-V255 VanDerWaalsContact CD1-CG2 3.44Å; L229-V255 HydrophobicContact CG-CG2 4.28Å; L229-L294 HydrophobicContact CD1-CD2 4.19Å; L229-L298 HydrophobicContact CB-CD1 4.23Å; L229-L298 HydrophobicContact CD2-CD1 3.64Å; L229-L298 HydrophobicContact CG-CD1 4.46Å; L229-L302 HydrophobicContact CD1-CB 4.49Å; L229-L302 HydrophobicContact CD1-CD2 4.04Å; L229-L302 HydrophobicContact CD2-CB 4.43Å; L229-L302 HydrophobicContact CD2-CD2 4.02Å
230	I	97.5	Very high	95.3	Very high	0 Å²	0	28.8 Å²	28.8	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-54.6	-51.9	176.4	-69.7	166.5	0	0	0	109.8	V205 L208 A226 V227 F233 I234 M244 A248 S251	V205-I230 HydrophobicContact CG2-CD1 4.33Å; L208-I230 HydrophobicContact CD2-CD1 3.74Å; A226-I230 VanDerWaalsContact O-CG1 3.27Å; A226-I230 WeakPolarHBondContact O-CG1 3.43Å; A226-I230 PolarHBondContact O-N 3.31Å; V227-I230 WeakPolarHBondContact O-CB 3.47Å; V227-I230 PolarHBondContact O-N 3.09Å; I230-F233 PolarHBondContact O-N 3.14Å; I230-I234 HydrophobicContact CG2-CD1 3.6Å; I230-I234 WeakPolarHBondContact O-CD1 3.45Å; I230-I234 VanDerWaalsContact O-CG1 3.25Å; I230-I234 WeakPolarHBondContact O-CG1 3.26Å; I230-I234 PolarHBondContact O-N 3.11Å; I230-M244 HydrophobicContact CG2-CE 3.61Å; I230-A248 HydrophobicContact CD1-CB 3.75Å; I230-A248 HydrophobicContact CG1-CB 4.41Å; I230-S251 WeakPolarHBondContact CD1-OG 3.31Å; I230-S251 WeakPolarHBondContact CG1-OG 3.4Å
231	D	97	Very high	95.4	Very high	0 Å²	0	29.7 Å²	29.7	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-69	-44.3	-173.7	-70.9	-39.9	0	0	0	111.6	P180 N182 R201 V227 N228 L229 F233 I234 V235 Y400	P180-D231 HydrophobicContact CB-CB 3.79Å; P180-D231 HydrophobicContact CG-CB 3.48Å; P180-D231 VanDerWaalsContact CG-CB 3.48Å; N182-D231 VanDerWaalsContact ND2-CB 3.28Å; N182-D231 WeakPolarHBondContact ND2-CB 3.46Å; N182-D231 PolarHBondContact ND2-OD1 2.8Å; N182-D231 PolarHBondContact OD1-O 3.43Å; R201-D231 IonicContact CZ-OD1 3.58Å; R201-D231 IonicContact CZ-OD2 2.8Å; R201-D231 IonicContact NE-OD1 3.71Å; R201-D231 PolarHBondContact NE-OD1 3.29Å; R201-D231 IonicContact NE-OD2 2.69Å; R201-D231 IonicContact NH2-OD1 3.2Å; R201-D231 PolarHBondContact NH2-OD1 3.18Å; R201-D231 IonicContact NH2-OD2 3.75Å; R201-D231 PolarHBondContact NH2-OD2 2.99Å; V227-D231 WeakPolarHBondContact CG1-OD2 3.27Å; V227-D231 PolarHBondContact O-N 3.34Å; N228-D231 PolarHBondContact O-N 2.73Å; L229-D231 VanDerWaalsContact C-N 3.3Å; L229-D231 PolarHBondContact O-N 3.21Å; D231-F233 VanDerWaalsContact C-N 3.27Å; D231-F233 PolarHBondContact O-N 3.47Å; D231-I234 PolarHBondContact O-N 3.37Å; D231-V235 VanDerWaalsContact O-CG2 3.28Å; D231-V235 WeakPolarHBondContact O-CG2 3.3Å; D231-V235 PolarHBondContact O-N 3.37Å; D231-V235 VanDerWaalsContact O-N 3.16Å; D231-Y400 VanDerWaalsContact OD2-CE2 3.25Å; D231-Y400 WeakPolarHBondContact OD2-CE2 3.38Å; D231-Y400 PolarHBondContact OD2-OH 3.35Å
232	R	96.6	Very high	95.4	Very high	19 Å²	19	32.6 Å²	32.6	7%	0.072	16%	0.156	C	C	.	.	H	α-helix	trans	-60.7	-37.9	173.8	-72	172.5	70.3	-152.9	5.3	111.9	Y178 P180 N228 L229 K236 L298 D301	Y178-R232 VanDerWaalsContact CD1-CZ 3.48Å; P180-R232 HydrophobicContact CB-CG 4.32Å; N228-R232 WeakPolarHBondContact O-CB 3.32Å; N228-R232 VanDerWaalsContact O-CG 3.29Å; N228-R232 WeakPolarHBondContact O-CG 3.34Å; N228-R232 PolarHBondContact O-N 3.41Å; N228-R232 WeakPolarHBondContact OD1-CD 3.27Å; L229-R232 PolarHBondContact O-N 2.85Å; R232-K236 PolarHBondContact O-N 3.28Å; R232-L298 HydrophobicContact CB-CD2 3.85Å; R232-D301 IonicContact CZ-OD2 2.82Å; R232-D301 PolarHBondContact NH1-O 3.48Å; R232-D301 IonicContact NH1-OD2 2.95Å; R232-D301 IonicContact NH2-OD2 2.76Å; R232-D301 PolarHBondContact NH2-OD2 3.45Å
233	F	97.2	Very high	95.5	Very high	4 Å²	4	33.4 Å²	33.4	2%	0.018	16%	0.159	C	C	.	.	H	α-helix	trans	-67.2	-45.2	178.9	-176.2	-98.5	0	0	0	111.8	L229 I230 D231 V235 K236 V237 V239 V247 M290 I293 L294 K297	L229-F233 WeakPolarHBondContact O-CB 3.31Å; L229-F233 PolarHBondContact O-N 3.28Å; I230-F233 PolarHBondContact O-N 3.14Å; D231-F233 VanDerWaalsContact C-N 3.27Å; D231-F233 PolarHBondContact O-N 3.47Å; F233-V235 VanDerWaalsContact C-N 3.27Å; F233-V235 PolarHBondContact O-N 3.46Å; F233-K236 PolarHBondContact O-N 2.9Å; F233-K236 VanDerWaalsContact O-N 3.1Å; F233-V237 HydrophobicContact CD1-CB 4.4Å; F233-V237 HydrophobicContact CD2-CG2 4.04Å; F233-V237 HydrophobicContact CE1-CB 4.05Å; F233-V237 HydrophobicContact CE1-CG1 4.16Å; F233-V237 HydrophobicContact CE1-CG2 4.41Å; F233-V237 HydrophobicContact CE2-CB 4.21Å; F233-V237 HydrophobicContact CE2-CG2 3.67Å; F233-V237 HydrophobicContact CZ-CB 3.95Å; F233-V237 HydrophobicContact CZ-CG1 3.96Å; F233-V237 HydrophobicContact CZ-CG2 3.88Å; F233-V237 WeakPolarHBondContact O-CB 3.49Å; F233-V237 PolarHBondContact O-N 3.24Å; F233-V239 HydrophobicContact CD1-CG2 3.87Å; F233-V239 HydrophobicContact CE1-CG2 3.65Å; F233-V247 HydrophobicContact CD1-CG1 3.6Å; F233-V247 HydrophobicContact CD1-CG2 4.15Å; F233-V247 HydrophobicContact CE1-CG1 4.04Å; F233-V247 HydrophobicContact CE1-CG2 3.72Å; F233-V247 HydrophobicContact CG-CG1 4.43Å; F233-M290 HydrophobicContact CZ-SD 4.32Å; F233-I293 HydrophobicContact CE2-CG2 4.28Å; F233-I293 HydrophobicContact CZ-CG2 4.3Å; F233-L294 HydrophobicContact CB-CD1 4.5Å; F233-L294 HydrophobicContact CD2-CB 4.15Å; F233-L294 HydrophobicContact CD2-CD1 4.42Å; F233-L294 HydrophobicContact CD2-CG 3.99Å; F233-L294 HydrophobicContact CE2-CB 4.15Å; F233-L294 HydrophobicContact CE2-CG 4.5Å; F233-L294 HydrophobicContact CG-CD1 4.4Å; F233-L294 HydrophobicContact CG-CG 4.43Å; F233-K297 HydrophobicContact CD2-CB 4.33Å; F233-K297 HydrophobicContact CE2-CB 4.08Å; F233-K297 HydrophobicContact CE2-CG 4.3Å
234	I	96.1	Very high	95.5	Very high	7 Å²	7	33.5 Å²	33.5	4%	0.036	16%	0.159	C	C	.	.	H	α-helix	trans	-65.7	-30.1	179.3	-64.1	162.1	0	0	0	112	F184 L185 R201 I230 D231 V237 V239 M244	F184-I234 HydrophobicContact CE2-CG2 4.41Å; F184-I234 HydrophobicContact CZ-CG2 4.08Å; L185-I234 HydrophobicContact CD1-CG2 4.47Å; L185-I234 HydrophobicContact CD2-CG2 3.9Å; R201-I234 HydrophobicContact CG-CD1 4.35Å; I230-I234 HydrophobicContact CG2-CD1 3.6Å; I230-I234 WeakPolarHBondContact O-CD1 3.45Å; I230-I234 VanDerWaalsContact O-CG1 3.25Å; I230-I234 WeakPolarHBondContact O-CG1 3.26Å; I230-I234 PolarHBondContact O-N 3.11Å; D231-I234 PolarHBondContact O-N 3.37Å; I234-V237 VanDerWaalsContact O-O 3.08Å; I234-V239 HydrophobicContact CG1-CG2 4.12Å; I234-M244 HydrophobicContact CD1-CE 3.67Å; I234-M244 HydrophobicContact CD1-SD 3.61Å; I234-M244 HydrophobicContact CG1-SD 4.32Å
235	V	94.6	Very high	95.5	Very high	63 Å²	63	35.6 Å²	35.6	38%	0.382	18%	0.176	S	C	.	.	H	α-helix	trans	-66.4	-40.5	172.6	176.4	0	0	0	0	111.3	P180 N182 F184 D231 F233	P180-V235 HydrophobicContact CB-CG2 3.95Å; N182-V235 WeakPolarHBondContact OD1-CG2 3.37Å; F184-V235 HydrophobicContact CE1-CG2 4.05Å; D231-V235 VanDerWaalsContact O-CG2 3.28Å; D231-V235 WeakPolarHBondContact O-CG2 3.3Å; D231-V235 PolarHBondContact O-N 3.37Å; D231-V235 VanDerWaalsContact O-N 3.16Å; F233-V235 VanDerWaalsContact C-N 3.27Å; F233-V235 PolarHBondContact O-N 3.46Å
236	K	94.3	Very high	95.5	Very high	115 Å²	115	34.9 Å²	34.9	50%	0.5	17%	0.173	S	C	.	.	H	α-helix	trans	-85.9	-27.7	-175.4	-72.1	-170.9	178.7	-178.2	0	113.9	R232 F233 K297 L298	R232-K236 PolarHBondContact O-N 3.28Å; F233-K236 PolarHBondContact O-N 2.9Å; F233-K236 VanDerWaalsContact O-N 3.1Å; K236-K297 WeakPolarHBondContact CD-O 3.35Å; K236-K297 PolarHBondContact NZ-O 3.42Å; K236-L298 HydrophobicContact CD-CD2 4.12Å
237	V	94.9	Very high	95.5	Very high	36 Å²	36	34.9 Å²	34.9	22%	0.218	17%	0.174	C	C	.	.	S	Bend	trans	-124.6	131.3	-171.6	-178.3	0	0	0	0	109.6	F233 I234 V239 K297	F233-V237 HydrophobicContact CD1-CB 4.4Å; F233-V237 HydrophobicContact CD2-CG2 4.04Å; F233-V237 HydrophobicContact CE1-CB 4.05Å; F233-V237 HydrophobicContact CE1-CG1 4.16Å; F233-V237 HydrophobicContact CE1-CG2 4.41Å; F233-V237 HydrophobicContact CE2-CB 4.21Å; F233-V237 HydrophobicContact CE2-CG2 3.67Å; F233-V237 HydrophobicContact CZ-CB 3.95Å; F233-V237 HydrophobicContact CZ-CG1 3.96Å; F233-V237 HydrophobicContact CZ-CG2 3.88Å; F233-V237 WeakPolarHBondContact O-CB 3.49Å; F233-V237 PolarHBondContact O-N 3.24Å; I234-V237 VanDerWaalsContact O-O 3.08Å; V237-V239 HydrophobicContact CG1-CG2 4.43Å; V237-V239 PolarHBondContact O-N 3.35Å; V237-K297 HydrophobicContact CG2-CB 4.02Å; V237-K297 HydrophobicContact CG2-CD 4.29Å; V237-K297 HydrophobicContact CG2-CG 3.89Å
238	K	93.6	Very high	95.5	Very high	157 Å²	157	35.1 Å²	35.1	68%	0.683	18%	0.175	S	C	*	.			trans	-70.6	92.3	171.5	-174.9	-178.4	173.7	-174.8	0	109.8
239	V	95.2	Very high	95.4	Very high	12 Å²	12	34.8 Å²	34.8	7%	0.073	17%	0.174	C	C	.	.			trans	-80.7	128.3	177.5	-176.3	0	0	0	0	110	V196 F233 I234 V237 V247	V196-V239 HydrophobicContact CG2-CB 3.87Å; V196-V239 HydrophobicContact CG2-CG1 3.82Å; V196-V239 PolarHBondContact N-O 3.46Å; F233-V239 HydrophobicContact CD1-CG2 3.87Å; F233-V239 HydrophobicContact CE1-CG2 3.65Å; I234-V239 HydrophobicContact CG1-CG2 4.12Å; V237-V239 HydrophobicContact CG1-CG2 4.43Å; V237-V239 PolarHBondContact O-N 3.35Å; V239-V247 HydrophobicContact CG1-CG2 4.07Å; V239-V247 HydrophobicContact CG2-CG2 4.4Å
240	K	94.5	Very high	95.3	Very high	82 Å²	82	34.8 Å²	34.8	36%	0.357	17%	0.174	S	C	.	.			trans	-77.8	143.4	168.7	-63.8	-179.3	178.5	170.7	0	109.3	K242 Y243	K240-K242 HydrophobicContact CB-CG 4.21Å; K240-K242 PolarHBondContact O-N 3.4Å; K240-Y243 HydrophobicContact CB-CD2 3.89Å; K240-Y243 HydrophobicContact CB-CE2 4.24Å; K240-Y243 HydrophobicContact CD-CE2 4.31Å; K240-Y243 PolarHBondContact O-N 3.04Å
241	P	94.6	Very high	95.2	Very high	42 Å²	42	34.8 Å²	34.8	27%	0.273	17%	0.174	S	C	.	.	G	3₁₀ helix	trans	-47.2	-38.7	-180	-34.6	37.9	0	0	0	115.3	D194 K195 L200 Y243 M244	D194-P241 VanDerWaalsContact C-CD 3.47Å; D194-P241 WeakPolarHBondContact O-CD 3.24Å; K195-P241 WeakPolarHBondContact O-CG 3.35Å; L200-P241 HydrophobicContact CD2-CB 3.58Å; L200-P241 HydrophobicContact CD2-CG 4.23Å; P241-Y243 PolarHBondContact O-N 2.87Å; P241-M244 WeakPolarHBondContact O-CB 3.23Å; P241-M244 PolarHBondContact O-N 3.36Å
242	K	92.2	Very high	95.1	Very high	120 Å²	120	34.8 Å²	34.8	52%	0.522	17%	0.174	S	C	.	.	G	3₁₀ helix	trans	-62	-23.4	179.2	63.6	173.6	177.9	161.5	0	114.8	K240	K240-K242 HydrophobicContact CB-CG 4.21Å; K240-K242 PolarHBondContact O-N 3.4Å
243	Y	93.9	Very high	94.9	Very high	20 Å²	20	34.4 Å²	34.4	8%	0.078	17%	0.174	C	C	.	.	G	3₁₀ helix	trans	-97.6	-7	-179.6	-59.7	-63.3	0	0	0	113	K240 P241 A245 C246 V247 L479 D480 I482	K240-Y243 HydrophobicContact CB-CD2 3.89Å; K240-Y243 HydrophobicContact CB-CE2 4.24Å; K240-Y243 HydrophobicContact CD-CE2 4.31Å; K240-Y243 PolarHBondContact O-N 3.04Å; P241-Y243 PolarHBondContact O-N 2.87Å; Y243-A245 PolarHBondContact O-N 3.39Å; Y243-C246 WeakPolarHBondContact O-CA 3.46Å; Y243-C246 WeakPolarHBondContact O-CB 3.46Å; Y243-C246 PolarHBondContact O-N 3.38Å; Y243-V247 WeakPolarHBondContact O-CG2 3.35Å; Y243-V247 PolarHBondContact O-N 3.1Å; Y243-L479 HydrophobicContact CD1-CD2 4.08Å; Y243-L479 HydrophobicContact CE1-CD2 3.76Å; Y243-D480 PolarHBondContact OH-O 2.72Å; Y243-I482 HydrophobicContact CE1-CD1 4.19Å; Y243-I482 HydrophobicContact CE1-CG1 3.91Å; Y243-I482 HydrophobicContact CE2-CG1 4.03Å
244	M	95.7	Very high	94.7	Very high	1 Å²	1	34.3 Å²	34.3	1%	0.005	17%	0.174	C	C	.	.	H	α-helix	trans	-60.3	-42.3	-172.6	-176.2	58.3	-150.7	0	0	112.9	V196 L200 R201 A204 I230 I234 P241 C246 V247 A248	V196-M244 HydrophobicContact CG1-CG 4.39Å; V196-M244 HydrophobicContact CG1-SD 4Å; V196-M244 HydrophobicContact CG2-CB 4.15Å; V196-M244 HydrophobicContact CG2-CG 4.27Å; V196-M244 HydrophobicContact CG2-SD 3.96Å; L200-M244 HydrophobicContact CD2-CB 4.07Å; L200-M244 HydrophobicContact CD2-CG 4.32Å; L200-M244 HydrophobicContact CG-CB 4.26Å; L200-M244 HydrophobicContact CG-CG 4.08Å; R201-M244 HydrophobicContact CG-CE 4.43Å; A204-M244 HydrophobicContact CB-CE 3.57Å; A204-M244 HydrophobicContact CB-CG 3.79Å; I230-M244 HydrophobicContact CG2-CE 3.61Å; I234-M244 HydrophobicContact CD1-CE 3.67Å; I234-M244 HydrophobicContact CD1-SD 3.61Å; I234-M244 HydrophobicContact CG1-SD 4.32Å; P241-M244 WeakPolarHBondContact O-CB 3.23Å; P241-M244 PolarHBondContact O-N 3.36Å; M244-C246 VanDerWaalsContact C-N 3.31Å; M244-C246 PolarHBondContact O-N 2.99Å; M244-V247 PolarHBondContact O-N 2.93Å; M244-A248 PolarHBondContact O-N 3.29Å
245	A	95	Very high	94.5	Very high	46 Å²	46	34.1 Å²	34.1	38%	0.38	17%	0.173	S	C	.	.	H	α-helix	trans	-64.8	-36	175.7	0	0	0	0	0	112.3	Y243 A249 C280	Y243-A245 PolarHBondContact O-N 3.39Å; A245-A249 WeakPolarHBondContact O-CB 3.38Å; A245-A249 PolarHBondContact O-N 2.89Å; A245-C280 HydrophobicContact CB-CB 4.13Å
246	C	95.1	Very high	94.3	Very high	1 Å²	1	31.2 Å²	31.2	1%	0.007	16%	0.156	C	C	.	.	H	α-helix	trans	-69.2	-42.5	176.4	-171	0	0	0	0	111.3	Y243 M244 A248 A249 A250 C280	Y243-C246 WeakPolarHBondContact O-CA 3.46Å; Y243-C246 WeakPolarHBondContact O-CB 3.46Å; Y243-C246 PolarHBondContact O-N 3.38Å; M244-C246 VanDerWaalsContact C-N 3.31Å; M244-C246 PolarHBondContact O-N 2.99Å; C246-A248 VanDerWaalsContact C-N 3.33Å; C246-A248 PolarHBondContact O-N 2.74Å; C246-A249 PolarHBondContact O-N 3.3Å; C246-A250 VanDerWaalsContact O-CB 3.27Å; C246-A250 WeakPolarHBondContact O-CB 3.41Å; C246-A250 PolarHBondContact O-N 2.86Å; C246-C280 HydrophobicContact CB-CB 4.23Å
247	V	96.6	Very high	94	Very high	1 Å²	1	29.7 Å²	29.7	1%	0.006	15%	0.149	C	C	.	.	H	α-helix	trans	-57.9	-45.5	173.8	171	0	0	0	0	111.1	F233 V239 Y243 M244 A250 S251 M290	F233-V247 HydrophobicContact CD1-CG1 3.6Å; F233-V247 HydrophobicContact CD1-CG2 4.15Å; F233-V247 HydrophobicContact CE1-CG1 4.04Å; F233-V247 HydrophobicContact CE1-CG2 3.72Å; F233-V247 HydrophobicContact CG-CG1 4.43Å; V239-V247 HydrophobicContact CG1-CG2 4.07Å; V239-V247 HydrophobicContact CG2-CG2 4.4Å; Y243-V247 WeakPolarHBondContact O-CG2 3.35Å; Y243-V247 PolarHBondContact O-N 3.1Å; M244-V247 PolarHBondContact O-N 2.93Å; V247-A250 PolarHBondContact O-N 3.4Å; V247-S251 WeakPolarHBondContact O-CB 3.44Å; V247-S251 PolarHBondContact O-N 3.49Å; V247-S251 PolarHBondContact O-OG 3.31Å; V247-M290 HydrophobicContact CG2-CE 4.48Å; V247-M290 HydrophobicContact CG2-CG 4.41Å; V247-M290 HydrophobicContact CG2-SD 3.94Å
248	A	96.4	Very high	93.6	Very high	4 Å²	4	30.1 Å²	30.1	3%	0.033	15%	0.15	C	C	.	.	H	α-helix	trans	-65.7	-36.8	178.2	0	0	0	0	0	113.2	A204 I230 M244 C246 S251 Y252	A204-A248 HydrophobicContact CB-CB 4.36Å; I230-A248 HydrophobicContact CD1-CB 3.75Å; I230-A248 HydrophobicContact CG1-CB 4.41Å; M244-A248 PolarHBondContact O-N 3.29Å; C246-A248 VanDerWaalsContact C-N 3.33Å; C246-A248 PolarHBondContact O-N 2.74Å; A248-S251 PolarHBondContact O-OG 3.48Å; A248-Y252 PolarHBondContact O-N 3.1Å
249	A	94.8	Very high	93.1	Very high	1 Å²	1	23.6 Å²	23.6	1%	0.008	12%	0.124	C	C	.	.	H	α-helix	trans	-70.4	-41.2	174.3	0	0	0	0	0	111.8	A245 C246 Y252 C253 I274 T278 C280 L287	A245-A249 WeakPolarHBondContact O-CB 3.38Å; A245-A249 PolarHBondContact O-N 2.89Å; C246-A249 PolarHBondContact O-N 3.3Å; A249-Y252 WeakPolarHBondContact O-CB 3.21Å; A249-Y252 PolarHBondContact O-N 3.28Å; A249-C253 PolarHBondContact O-N 2.74Å; A249-C253 PolarHBondContact O-SG 3.24Å; A249-I274 HydrophobicContact CB-CG2 4Å; A249-T278 HydrophobicContact CB-CG2 4.28Å; A249-C280 HydrophobicContact CB-CB 4.43Å; A249-L287 HydrophobicContact CB-CD1 3.69Å
250	A	95.3	Very high	92.1	Very high	0 Å²	0	23.6 Å²	23.6	0%	0	13%	0.125	C	C	.	.	H	α-helix	trans	-66.6	-43.9	-179	0	0	0	0	0	111.6	C246 V247 Y252 C253 A254 L287 M290 E291	C246-A250 VanDerWaalsContact O-CB 3.27Å; C246-A250 WeakPolarHBondContact O-CB 3.41Å; C246-A250 PolarHBondContact O-N 2.86Å; V247-A250 PolarHBondContact O-N 3.4Å; A250-Y252 VanDerWaalsContact C-N 3.26Å; A250-Y252 PolarHBondContact O-N 3.15Å; A250-C253 WeakPolarHBondContact O-CB 3.47Å; A250-C253 PolarHBondContact O-N 2.97Å; A250-A254 PolarHBondContact O-N 2.96Å; A250-L287 HydrophobicContact CB-CD1 3.91Å; A250-M290 HydrophobicContact CB-CB 3.93Å; A250-M290 HydrophobicContact CB-CG 3.67Å; A250-E291 HydrophobicContact CB-CB 4.46Å
251	S	96.1	Very high	90.9	Very high	0 Å²	0	24.6 Å²	24.6	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-59.7	-39.2	175	65.6	0	0	0	0	111.8	I230 V247 A248 A254 V255	I230-S251 WeakPolarHBondContact CD1-OG 3.31Å; I230-S251 WeakPolarHBondContact CG1-OG 3.4Å; V247-S251 WeakPolarHBondContact O-CB 3.44Å; V247-S251 PolarHBondContact O-N 3.49Å; V247-S251 PolarHBondContact O-OG 3.31Å; A248-S251 PolarHBondContact O-OG 3.48Å; S251-A254 PolarHBondContact O-N 3.08Å; S251-V255 WeakPolarHBondContact O-CG2 3.41Å; S251-V255 PolarHBondContact O-N 3.15Å; S251-V255 VanDerWaalsContact O-N 3.15Å
252	Y	93.9	Very high	89.5	Confident	0 Å²	0	27.8 Å²	27.8	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-66.1	-42	176.2	-170.8	-106.9	0	0	0	112.1	L208 L211 H212 F216 L218 T222 A226 A248 A249 A250 V255 C256 I274	L208-Y252 HydrophobicContact CD1-CD1 4.36Å; L208-Y252 HydrophobicContact CD1-CD2 3.95Å; L208-Y252 HydrophobicContact CD1-CG 3.73Å; L208-Y252 HydrophobicContact CD2-CD2 4.45Å; L208-Y252 HydrophobicContact CG-CD2 4.38Å; L211-Y252 HydrophobicContact CD2-CD1 4.11Å; L211-Y252 HydrophobicContact CD2-CE1 4.21Å; H212-Y252 HydrophobicContact CB-CE2 4.37Å; H212-Y252 AromaticContact CD2-CE2 3.76Å; H212-Y252 AromaticContact CD2-CZ 4Å; H212-Y252 PolarHBondContact CD2-OH 3.03Å; F216-Y252 AromaticContact CD2-CE1 3.62Å; F216-Y252 HydrophobicContact CD2-CE1 3.62Å; F216-Y252 AromaticContact CE2-CE1 3.98Å; F216-Y252 HydrophobicContact CE2-CE1 3.98Å; F216-Y252 HydrophobicContact CG-CE1 4.41Å; L218-Y252 WeakPolarHBondContact CD1-OH 3.41Å; T222-Y252 HydrophobicContact CG2-CE2 4.15Å; A226-Y252 HydrophobicContact CB-CD2 4.02Å; A248-Y252 PolarHBondContact O-N 3.1Å; A249-Y252 WeakPolarHBondContact O-CB 3.21Å; A249-Y252 PolarHBondContact O-N 3.28Å; A250-Y252 VanDerWaalsContact C-N 3.26Å; A250-Y252 PolarHBondContact O-N 3.15Å; Y252-V255 PolarHBondContact O-N 3.28Å; Y252-C256 WeakPolarHBondContact O-CB 3.45Å; Y252-C256 PolarHBondContact O-N 3.04Å; Y252-C256 PolarHBondContact O-SG 2.88Å; Y252-I274 HydrophobicContact CD1-CD1 4.27Å
253	C	92	Very high	88.1	Confident	10 Å²	10	26.7 Å²	26.7	7%	0.068	16%	0.156	C	C	.	.	H	α-helix	trans	-59.8	-47	174.1	-65	0	0	0	0	112	A249 A250 V255 C256 K257 I274	A249-C253 PolarHBondContact O-N 2.74Å; A249-C253 PolarHBondContact O-SG 3.24Å; A250-C253 WeakPolarHBondContact O-CB 3.47Å; A250-C253 PolarHBondContact O-N 2.97Å; C253-V255 VanDerWaalsContact C-N 3.32Å; C253-V255 PolarHBondContact O-N 2.91Å; C253-C256 PolarHBondContact O-N 3.43Å; C253-K257 PolarHBondContact O-N 3.46Å; C253-I274 WeakPolarHBondContact SG-CD1 3.38Å
254	A	93.2	Very high	86.3	Confident	3 Å²	3	35 Å²	35	3%	0.025	19%	0.193	C	C	.	.	H	α-helix	trans	-56.5	-46.2	179.3	0	0	0	0	0	111.5	L229 A250 S251 K257 L258 E291 L302	L229-A254 HydrophobicContact CD1-CB 4.38Å; A250-A254 PolarHBondContact O-N 2.96Å; S251-A254 PolarHBondContact O-N 3.08Å; A254-K257 PolarHBondContact O-N 3.16Å; A254-L258 PolarHBondContact O-N 2.92Å; A254-E291 HydrophobicContact CB-CG 3.89Å; A254-L302 HydrophobicContact CB-CD1 4.17Å
255	V	92.7	Very high	84.5	Confident	3 Å²	3	42 Å²	42	2%	0.018	23%	0.231	C	C	.	.	H	α-helix	trans	-70.7	-36.4	178.7	-179.6	0	0	0	0	112.1	T222 K225 A226 L229 S251 Y252 C253 K257 L258 S259	T222-V255 HydrophobicContact CG2-CB 4.38Å; T222-V255 HydrophobicContact CG2-CG1 3.72Å; K225-V255 HydrophobicContact CB-CG1 3.74Å; K225-V255 HydrophobicContact CB-CG2 3.93Å; K225-V255 HydrophobicContact CD-CG1 4.46Å; A226-V255 HydrophobicContact CB-CG2 4.25Å; L229-V255 HydrophobicContact CD1-CG2 3.44Å; L229-V255 VanDerWaalsContact CD1-CG2 3.44Å; L229-V255 HydrophobicContact CG-CG2 4.28Å; S251-V255 WeakPolarHBondContact O-CG2 3.41Å; S251-V255 PolarHBondContact O-N 3.15Å; S251-V255 VanDerWaalsContact O-N 3.15Å; Y252-V255 PolarHBondContact O-N 3.28Å; C253-V255 VanDerWaalsContact C-N 3.32Å; C253-V255 PolarHBondContact O-N 2.91Å; V255-K257 VanDerWaalsContact C-N 3.28Å; V255-K257 PolarHBondContact O-N 3.16Å; V255-L258 PolarHBondContact O-N 3.46Å; V255-S259 WeakPolarHBondContact O-CB 3.26Å; V255-S259 PolarHBondContact O-N 2.93Å
256	C	89.4	Confident	83	Confident	2 Å²	2	41.7 Å²	41.7	1%	0.014	22%	0.224	C	C	.	.	H	α-helix	trans	-60.2	-40.7	174.8	-69.8	0	0	0	0	111.5	L218 Y252 C253 S260 P269	L218-C256 VanDerWaalsContact CD1-SG 3.5Å; Y252-C256 WeakPolarHBondContact O-CB 3.45Å; Y252-C256 PolarHBondContact O-N 3.04Å; Y252-C256 PolarHBondContact O-SG 2.88Å; C253-C256 PolarHBondContact O-N 3.43Å; C256-S260 WeakPolarHBondContact O-CB 3.21Å; C256-S260 PolarHBondContact O-N 2.76Å; C256-S260 PolarHBondContact O-OG 2.72Å; C256-P269 HydrophobicContact CB-CG 4.47Å
257	K	88	Confident	81.5	Confident	82 Å²	82	50 Å²	50	36%	0.357	26%	0.264	S	S	.	.	H	α-helix	trans	-64.6	-44.8	174.2	-75.3	167.8	173.3	179.5	0	112	C253 A254 V255 S259 S260 S261 L268 E291	C253-K257 PolarHBondContact O-N 3.46Å; A254-K257 PolarHBondContact O-N 3.16Å; V255-K257 VanDerWaalsContact C-N 3.28Å; V255-K257 PolarHBondContact O-N 3.16Å; K257-S259 PolarHBondContact O-N 3.25Å; K257-S260 PolarHBondContact O-N 3.06Å; K257-S261 PolarHBondContact O-N 3Å; K257-L268 HydrophobicContact CB-CD2 4.33Å; K257-L268 HydrophobicContact CG-CD2 3.55Å; K257-E291 WeakPolarHBondContact CD-OE1 3.32Å; K257-E291 WeakPolarHBondContact CE-OE1 3.28Å; K257-E291 IonicContact NZ-OE1 3.04Å; K257-E291 PolarHBondContact NZ-OE1 3.47Å; K257-E291 IonicContact NZ-OE2 2.69Å; K257-E291 PolarHBondContact NZ-OE2 2.98Å
258	L	87.1	Confident	80.3	Confident	45 Å²	45	53.8 Å²	53.8	24%	0.236	28%	0.284	C	S	.	.	H	α-helix	trans	-59.2	-47.1	176	-179.7	63.8	0	0	0	112	A254 V255 S260 S261 N262 L302 D303	A254-L258 PolarHBondContact O-N 2.92Å; V255-L258 PolarHBondContact O-N 3.46Å; L258-S260 VanDerWaalsContact C-N 3.34Å; L258-S260 PolarHBondContact O-N 2.75Å; L258-S261 WeakPolarHBondContact O-CB 3.38Å; L258-S261 PolarHBondContact O-N 3.33Å; L258-N262 PolarHBondContact O-N 3.34Å; L258-L302 HydrophobicContact CD2-CB 4.32Å; L258-D303 HydrophobicContact CD2-CB 3.94Å
259	S	83.8	Confident	79.3	Confident	20 Å²	20	54.5 Å²	54.5	14%	0.14	29%	0.288	C	S	.	.	H	α-helix	trans	-64.8	-37.7	179.3	-174.8	0	0	0	0	112.4	V255 K257 N262 N263	V255-S259 WeakPolarHBondContact O-CB 3.26Å; V255-S259 PolarHBondContact O-N 2.93Å; K257-S259 PolarHBondContact O-N 3.25Å; S259-N262 PolarHBondContact O-N 3.09Å; S259-N263 PolarHBondContact O-N 3.21Å
260	S	74.3	Confident	78.9	Confident	13 Å²	13	57.9 Å²	57.9	9%	0.091	31%	0.306	C	S	.	.	H	α-helix	trans	-72.3	-31.8	178.7	-54.7	0	0	0	0	112.9	C256 K257 L258 N262 N263 L268	C256-S260 WeakPolarHBondContact O-CB 3.21Å; C256-S260 PolarHBondContact O-N 2.76Å; C256-S260 PolarHBondContact O-OG 2.72Å; K257-S260 PolarHBondContact O-N 3.06Å; L258-S260 VanDerWaalsContact C-N 3.34Å; L258-S260 PolarHBondContact O-N 2.75Å; S260-N262 VanDerWaalsContact C-N 3.26Å; S260-N262 PolarHBondContact O-N 3.16Å; S260-N263 CarbonylContact O-C 3.58Å; S260-N263 PolarHBondContact O-N 2.88Å; S260-N263 VanDerWaalsContact O-O 3.09Å; S260-L268 WeakPolarHBondContact OG-CD1 3.41Å; S260-L268 WeakPolarHBondContact OG-CG 3.43Å
261	S	69.1	Low	78.5	Confident	102 Å²	102	59.5 Å²	59.5	71%	0.713	32%	0.317	S	S	*	.	H	α-helix	trans	-59.3	-40.2	170.3	-170.7	0	0	0	0	111.3	K257 L258	K257-S261 PolarHBondContact O-N 3Å; L258-S261 WeakPolarHBondContact O-CB 3.38Å; L258-S261 PolarHBondContact O-N 3.33Å
262	N	65	Low	78.2	Confident	110 Å²	110	65.8 Å²	65.8	59%	0.588	35%	0.346	S	S	*	.	H	α-helix	trans	-76.9	-32	177.2	-66.9	-17.7	0	0	0	112.8	L258 S259 S260	L258-N262 PolarHBondContact O-N 3.34Å; S259-N262 PolarHBondContact O-N 3.09Å; S260-N262 VanDerWaalsContact C-N 3.26Å; S260-N262 PolarHBondContact O-N 3.16Å
263	N	63.6	Low	78	Confident	97 Å²	97	68.7 Å²	68.7	52%	0.519	36%	0.364	S	S	.	.			trans	-127.9	97.4	-177.6	-73.6	-52	0	0	0	111.7	S259 S260 N265 V266	S259-N263 PolarHBondContact O-N 3.21Å; S260-N263 CarbonylContact O-C 3.58Å; S260-N263 PolarHBondContact O-N 2.88Å; S260-N263 VanDerWaalsContact O-O 3.09Å; N263-N265 PolarHBondContact O-N 3.01Å; N263-V266 HydrophobicContact CB-CG2 3.96Å; N263-V266 PolarHBondContact O-N 3.36Å
264	K	56	Low	77.8	Confident	195 Å²	195	68.2 Å²	68.2	85%	0.848	36%	0.361	S	S	*	.	T	Hydrogen-bonded Turn	trans	-53.9	-5.8	178.2	62.7	179.1	178.7	178.8	0	117.3
265	N	56.8	Low	77.7	Confident	148 Å²	148	69.1 Å²	69.1	79%	0.791	37%	0.366	S	S	*	.	T	Hydrogen-bonded Turn	trans	-105.1	-3	-176	-68.1	-13.2	0	0	0	113.9	N263	N263-N265 PolarHBondContact O-N 3.01Å
266	V	63.3	Low	77.6	Confident	39 Å²	39	74.4 Å²	74.4	24%	0.236	39%	0.39	C	S	.	.			trans	-84.1	121.5	179.2	-177.8	0	0	0	0	108.9	L218 N263 L268	L218-V266 HydrophobicContact CD2-CG1 3.76Å; N263-V266 HydrophobicContact CB-CG2 3.96Å; N263-V266 PolarHBondContact O-N 3.36Å; V266-L268 PolarHBondContact O-N 3.33Å
267	M	65	Low	77.5	Confident	174 Å²	174	76.5 Å²	76.5	86%	0.857	40%	0.401	S	S	*	.			trans	-71.2	113.5	172.5	-162.9	-165.1	174.3	0	0	108.3
268	L	71.3	Confident	77.5	Confident	81 Å²	81	74.6 Å²	74.6	42%	0.424	40%	0.396	S	S	.	.	P	Polyproline II helix	trans	-62.2	132.1	174.6	-77.1	88.6	0	0	0	109.3	K257 S260 V266 D270	K257-L268 HydrophobicContact CB-CD2 4.33Å; K257-L268 HydrophobicContact CG-CD2 3.55Å; S260-L268 WeakPolarHBondContact OG-CD1 3.41Å; S260-L268 WeakPolarHBondContact OG-CG 3.43Å; V266-L268 PolarHBondContact O-N 3.33Å; L268-D270 PolarHBondContact O-N 3.02Å
269	P	75.2	Confident	77.5	Confident	19 Å²	19	80.5 Å²	80.5	12%	0.123	42%	0.415	C	S	.	.	P	Polyproline II helix	trans	-56.6	127.9	164.9	-25.5	36.5	0	0	0	110.3	F216 C256 I274	F216-P269 HydrophobicContact CD1-CB 4.05Å; F216-P269 HydrophobicContact CD1-CG 3.58Å; F216-P269 HydrophobicContact CD2-CG 4.42Å; F216-P269 HydrophobicContact CE1-CB 3.38Å; F216-P269 HydrophobicContact CE1-CG 3.46Å; F216-P269 VanDerWaalsContact CE1-CG 3.46Å; F216-P269 HydrophobicContact CE2-CB 4.33Å; F216-P269 HydrophobicContact CE2-CG 4.3Å; F216-P269 HydrophobicContact CG-CG 4.07Å; F216-P269 HydrophobicContact CZ-CB 3.55Å; F216-P269 HydrophobicContact CZ-CG 3.85Å; C256-P269 HydrophobicContact CB-CG 4.47Å; P269-I274 HydrophobicContact CB-CD1 3.39Å; P269-I274 HydrophobicContact CB-CG1 3.72Å; P269-I274 HydrophobicContact CG-CD1 4.11Å
270	D	85.2	Confident	77.7	Confident	72 Å²	72	79.8 Å²	79.8	39%	0.385	41%	0.41	S	S	.	.	P	Polyproline II helix	trans	-64.6	130.9	169	163.1	54.9	0	0	0	109.5	L268 E272 T273 I274	L268-D270 PolarHBondContact O-N 3.02Å; D270-E272 PolarHBondContact O-N 2.98Å; D270-E272 WeakPolarHBondContact OD2-CB 3.46Å; D270-E272 PolarHBondContact OD2-N 2.86Å; D270-T273 VanDerWaalsContact O-CB 3.32Å; D270-T273 WeakPolarHBondContact O-CB 3.4Å; D270-T273 PolarHBondContact O-N 3.46Å; D270-T273 PolarHBondContact OD2-N 3.04Å; D270-T273 PolarHBondContact OD2-OG1 3.25Å; D270-I274 PolarHBondContact O-N 3.49Å; D270-I274 VanDerWaalsContact O-N 3.1Å
271	P	87.2	Confident	78.1	Confident	34 Å²	34	80.8 Å²	80.8	22%	0.221	42%	0.423	C	S	.	.	H	α-helix	trans	-57.5	-33.6	-178.4	21.7	-35.2	0	0	0	113	T273 I274 V275 A284 L287	P271-T273 VanDerWaalsContact C-N 3.32Å; P271-T273 PolarHBondContact O-N 3.41Å; P271-I274 PolarHBondContact O-N 3Å; P271-V275 WeakPolarHBondContact O-CG2 3.24Å; P271-V275 PolarHBondContact O-N 3.18Å; P271-A284 HydrophobicContact CB-CB 4.18Å; P271-A284 HydrophobicContact CG-CB 4.49Å; P271-L287 HydrophobicContact CB-CD2 4.09Å
272	E	90.2	Very high	78.9	Confident	133 Å²	133	76.6 Å²	76.6	62%	0.621	40%	0.395	S	S	*	.	H	α-helix	trans	-64.6	-40.4	176.3	-54.8	-174.8	167.4	0	0	111.4	D270 V275 H276 A284	D270-E272 PolarHBondContact O-N 2.98Å; D270-E272 WeakPolarHBondContact OD2-CB 3.46Å; D270-E272 PolarHBondContact OD2-N 2.86Å; E272-V275 PolarHBondContact O-N 3.46Å; E272-H276 WeakPolarHBondContact O-CB 3.39Å; E272-H276 PolarHBondContact O-N 3.17Å; E272-A284 HydrophobicContact CB-CB 4.43Å; E272-A284 HydrophobicContact CG-CB 3.7Å
273	T	89.1	Confident	80.1	Confident	61 Å²	61	75.3 Å²	75.3	37%	0.374	39%	0.389	S	S	.	.	H	α-helix	trans	-61.6	-43.7	175.2	-59.5	0	0	0	0	111.6	D270 P271 H276 I277	D270-T273 VanDerWaalsContact O-CB 3.32Å; D270-T273 WeakPolarHBondContact O-CB 3.4Å; D270-T273 PolarHBondContact O-N 3.46Å; D270-T273 PolarHBondContact OD2-N 3.04Å; D270-T273 PolarHBondContact OD2-OG1 3.25Å; P271-T273 VanDerWaalsContact C-N 3.32Å; P271-T273 PolarHBondContact O-N 3.41Å; T273-H276 PolarHBondContact O-N 3.17Å; T273-I277 HydrophobicContact CG2-CD1 3.71Å; T273-I277 HydrophobicContact CG2-CG1 4.49Å; T273-I277 VanDerWaalsContact O-CG1 3.3Å; T273-I277 WeakPolarHBondContact O-CG1 3.13Å; T273-I277 PolarHBondContact O-N 3.37Å
274	I	89.2	Confident	81.5	Confident	0 Å²	0	71.5 Å²	71.5	0%	0	37%	0.371	C	S	.	.	H	α-helix	trans	-62	-48	176.2	-71.3	-178.3	0	0	0	111	F216 A249 Y252 C253 P269 D270 P271 H276 I277 T278 L287	F216-I274 HydrophobicContact CE2-CG1 4.07Å; F216-I274 HydrophobicContact CZ-CD1 4.41Å; F216-I274 HydrophobicContact CZ-CG1 3.78Å; A249-I274 HydrophobicContact CB-CG2 4Å; Y252-I274 HydrophobicContact CD1-CD1 4.27Å; C253-I274 WeakPolarHBondContact SG-CD1 3.38Å; P269-I274 HydrophobicContact CB-CD1 3.39Å; P269-I274 HydrophobicContact CB-CG1 3.72Å; P269-I274 HydrophobicContact CG-CD1 4.11Å; D270-I274 PolarHBondContact O-N 3.49Å; D270-I274 VanDerWaalsContact O-N 3.1Å; P271-I274 PolarHBondContact O-N 3Å; I274-H276 VanDerWaalsContact C-N 3.27Å; I274-H276 PolarHBondContact O-N 3.43Å; I274-I277 PolarHBondContact O-N 3.19Å; I274-T278 HydrophobicContact CG2-CG2 4Å; I274-T278 WeakPolarHBondContact O-CB 3.2Å; I274-T278 WeakPolarHBondContact O-CG2 3.49Å; I274-T278 PolarHBondContact O-N 2.96Å; I274-T278 PolarHBondContact O-OG1 2.68Å; I274-L287 HydrophobicContact CB-CD2 4.27Å; I274-L287 HydrophobicContact CG2-CD2 4Å
275	V	91	Very high	83.3	Confident	21 Å²	21	65.3 Å²	65.3	13%	0.127	36%	0.356	C	S	.	.	H	α-helix	trans	-58.7	-42.7	177.3	171.2	0	0	0	0	110.9	P271 E272 I277 R279 G282 L287	P271-V275 WeakPolarHBondContact O-CG2 3.24Å; P271-V275 PolarHBondContact O-N 3.18Å; E272-V275 PolarHBondContact O-N 3.46Å; V275-I277 PolarHBondContact O-N 3.42Å; V275-R279 WeakPolarHBondContact O-CA 3.33Å; V275-R279 PolarHBondContact O-N 3.02Å; V275-G282 WeakPolarHBondContact CG1-O 3.36Å; V275-L287 HydrophobicContact CG2-CB 3.97Å; V275-L287 HydrophobicContact CG2-CD2 3.64Å; V275-L287 HydrophobicContact CG2-CG 4.38Å
276	H	89.7	Confident	85.1	Confident	114 Å²	114	60 Å²	60	53%	0.528	33%	0.328	S	S	.	.	H	α-helix	trans	-63.2	-41.9	-179.6	-169.5	89.3	0	0	0	112.4	E272 T273 I274 R279	E272-H276 WeakPolarHBondContact O-CB 3.39Å; E272-H276 PolarHBondContact O-N 3.17Å; T273-H276 PolarHBondContact O-N 3.17Å; I274-H276 VanDerWaalsContact C-N 3.27Å; I274-H276 PolarHBondContact O-N 3.43Å; H276-R279 PolarHBondContact CE1-NH2 3.04Å; H276-R279 PolarHBondContact NE2-NH2 3.11Å; H276-R279 WeakPolarHBondContact O-CD 3.04Å; H276-R279 PolarHBondContact O-NE 3.24Å; H276-R279 PolarHBondContact O-NH1 3.38Å; H276-R279 PolarHBondContact O-NH2 3.1Å
277	I	88.4	Confident	86.6	Confident	47 Å²	47	58.2 Å²	58.2	24%	0.241	32%	0.317	C	S	.	.	H	α-helix	trans	-77.9	-47.5	-178	-62.1	163.7	0	0	0	111.1	L211 F215 T273 I274 V275 R279	L211-I277 HydrophobicContact CD1-CB 3.84Å; L211-I277 HydrophobicContact CD1-CD1 4.34Å; L211-I277 HydrophobicContact CD1-CG2 3.31Å; F215-I277 HydrophobicContact CB-CD1 4.3Å; F215-I277 HydrophobicContact CD1-CD1 3.64Å; F215-I277 HydrophobicContact CD1-CG1 4.37Å; F215-I277 HydrophobicContact CD1-CG2 4.41Å; F215-I277 HydrophobicContact CD2-CD1 4.46Å; F215-I277 HydrophobicContact CD2-CG2 3.78Å; F215-I277 HydrophobicContact CE1-CD1 4.03Å; F215-I277 HydrophobicContact CE1-CG1 4.26Å; F215-I277 HydrophobicContact CE1-CG2 4.08Å; F215-I277 HydrophobicContact CE2-CG2 3.4Å; F215-I277 HydrophobicContact CG-CD1 3.88Å; F215-I277 HydrophobicContact CG-CG2 4.26Å; F215-I277 HydrophobicContact CZ-CG2 3.56Å; T273-I277 HydrophobicContact CG2-CD1 3.71Å; T273-I277 HydrophobicContact CG2-CG1 4.49Å; T273-I277 VanDerWaalsContact O-CG1 3.3Å; T273-I277 WeakPolarHBondContact O-CG1 3.13Å; T273-I277 PolarHBondContact O-N 3.37Å; I274-I277 PolarHBondContact O-N 3.19Å; V275-I277 PolarHBondContact O-N 3.42Å; I277-R279 VanDerWaalsContact C-N 3.31Å; I277-R279 PolarHBondContact O-N 3.23Å
278	T	87.6	Confident	88	Confident	42 Å²	42	52.8 Å²	52.8	26%	0.258	29%	0.291	S	S	.	.	H	α-helix	trans	-72.8	-23.3	-175.8	58.5	0	0	0	0	113.5	L211 A249 I274 C280	L211-T278 HydrophobicContact CD1-CG2 4.1Å; L211-T278 HydrophobicContact CD2-CG2 3.55Å; L211-T278 HydrophobicContact CG-CG2 4.34Å; A249-T278 HydrophobicContact CB-CG2 4.28Å; I274-T278 HydrophobicContact CG2-CG2 4Å; I274-T278 WeakPolarHBondContact O-CB 3.2Å; I274-T278 WeakPolarHBondContact O-CG2 3.49Å; I274-T278 PolarHBondContact O-N 2.96Å; I274-T278 PolarHBondContact O-OG1 2.68Å; T278-C280 PolarHBondContact O-N 3.21Å
279	R	87	Confident	89.1	Confident	168 Å²	168	53.9 Å²	53.9	63%	0.634	29%	0.289	S	S	*	.			trans	52.7	39.1	-174.9	-56.2	-65.5	-175.9	-159.4	-12	112.1	V275 H276 I277 G281	V275-R279 WeakPolarHBondContact O-CA 3.33Å; V275-R279 PolarHBondContact O-N 3.02Å; H276-R279 PolarHBondContact CE1-NH2 3.04Å; H276-R279 PolarHBondContact NE2-NH2 3.11Å; H276-R279 WeakPolarHBondContact O-CD 3.04Å; H276-R279 PolarHBondContact O-NE 3.24Å; H276-R279 PolarHBondContact O-NH1 3.38Å; H276-R279 PolarHBondContact O-NH2 3.1Å; I277-R279 VanDerWaalsContact C-N 3.31Å; I277-R279 PolarHBondContact O-N 3.23Å; R279-G281 PolarHBondContact O-N 2.93Å
280	C	87.3	Confident	90.1	Very high	5 Å²	5	53.6 Å²	53.6	3%	0.034	29%	0.286	C	S	.	.			trans	-67.1	-0.7	-173.8	63.7	0	0	0	0	115.7	A245 C246 A249 T278	A245-C280 HydrophobicContact CB-CB 4.13Å; C246-C280 HydrophobicContact CB-CB 4.23Å; A249-C280 HydrophobicContact CB-CB 4.43Å; T278-C280 PolarHBondContact O-N 3.21Å
281	G	82.5	Confident	90.6	Very high	34 Å²	34	51.4 Å²	51.4	35%	0.351	27%	0.274	S	S	.	.	S	Bend	trans	90.2	-2.4	173	0	0	0	0	0	115.7	R279	R279-G281 PolarHBondContact O-N 2.93Å
282	G	85.7	Confident	91	Very high	14 Å²	14	55.9 Å²	55.9	14%	0.144	29%	0.292	C	S	.	.	S	Bend	trans	-112.6	-175.9	176	0	0	0	0	0	113.7	V275 D286	V275-G282 WeakPolarHBondContact CG1-O 3.36Å; G282-D286 WeakPolarHBondContact CA-OD2 3.44Å
283	N	91.8	Very high	91.3	Very high	83 Å²	83	51.9 Å²	51.9	44%	0.444	27%	0.274	S	S	.	.			trans	-97.6	176.9	165	65.4	48.8	0	0	0	110.9	A285 D286 L287	N283-A285 VanDerWaalsContact C-N 3.28Å; N283-A285 PolarHBondContact O-N 3.18Å; N283-A285 VanDerWaalsContact OD1-CA 3.31Å; N283-A285 WeakPolarHBondContact OD1-CA 3.46Å; N283-A285 VanDerWaalsContact OD1-CB 3.26Å; N283-A285 WeakPolarHBondContact OD1-CB 3.37Å; N283-A285 PolarHBondContact OD1-N 2.82Å; N283-D286 PolarHBondContact N-OD2 3.12Å; N283-D286 PolarHBondContact ND2-OD2 3.15Å; N283-D286 VanDerWaalsContact ND2-OD2 3.1Å; N283-D286 PolarHBondContact O-N 3.21Å; N283-D286 PolarHBondContact OD1-N 3.07Å; N283-D286 PolarHBondContact OD1-OD2 3.4Å; N283-L287 PolarHBondContact O-N 3.28Å; N283-L287 VanDerWaalsContact O-N 3.12Å
284	A	93.1	Very high	91.7	Very high	18 Å²	18	49 Å²	49	15%	0.149	26%	0.257	C	S	.	.	H	α-helix	trans	-63.6	-30.9	179.1	0	0	0	0	0	113.4	P271 E272 L287 L288	P271-A284 HydrophobicContact CB-CB 4.18Å; P271-A284 HydrophobicContact CG-CB 4.49Å; E272-A284 HydrophobicContact CB-CB 4.43Å; E272-A284 HydrophobicContact CG-CB 3.7Å; A284-L287 WeakPolarHBondContact O-CB 3.43Å; A284-L287 PolarHBondContact O-N 2.89Å; A284-L288 WeakPolarHBondContact O-CG 3.32Å; A284-L288 PolarHBondContact O-N 3.13Å
285	A	93.8	Very high	92	Very high	65 Å²	65	51 Å²	51	54%	0.537	27%	0.267	S	S	.	.	H	α-helix	trans	-69.8	-37.8	175.1	0	0	0	0	0	112	N283 L287 L288 R289	N283-A285 VanDerWaalsContact C-N 3.28Å; N283-A285 PolarHBondContact O-N 3.18Å; N283-A285 VanDerWaalsContact OD1-CA 3.31Å; N283-A285 WeakPolarHBondContact OD1-CA 3.46Å; N283-A285 VanDerWaalsContact OD1-CB 3.26Å; N283-A285 WeakPolarHBondContact OD1-CB 3.37Å; N283-A285 PolarHBondContact OD1-N 2.82Å; A285-L287 VanDerWaalsContact C-N 3.29Å; A285-L287 PolarHBondContact O-N 3.21Å; A285-L288 PolarHBondContact O-N 3.09Å; A285-R289 WeakPolarHBondContact O-CB 3.42Å; A285-R289 PolarHBondContact O-N 3.37Å
286	D	93.4	Very high	92.3	Very high	37 Å²	37	53.4 Å²	53.4	20%	0.198	29%	0.285	C	S	.	.	H	α-helix	trans	-64	-38.1	174.3	-60.2	-40.7	0	0	0	111.2	G282 N283 M290 L479	G282-D286 WeakPolarHBondContact CA-OD2 3.44Å; N283-D286 PolarHBondContact N-OD2 3.12Å; N283-D286 PolarHBondContact ND2-OD2 3.15Å; N283-D286 VanDerWaalsContact ND2-OD2 3.1Å; N283-D286 PolarHBondContact O-N 3.21Å; N283-D286 PolarHBondContact OD1-N 3.07Å; N283-D286 PolarHBondContact OD1-OD2 3.4Å; D286-M290 WeakPolarHBondContact O-CB 3.47Å; D286-M290 PolarHBondContact O-N 2.89Å; D286-L479 HydrophobicContact CB-CD1 3.82Å
287	L	94.5	Very high	92.6	Very high	0 Å²	0	53.7 Å²	53.7	0%	0	29%	0.285	C	S	.	.	H	α-helix	trans	-63.9	-47.2	175.8	-178	66.1	0	0	0	111.2	A249 A250 P271 I274 V275 N283 A284 A285 M290 E291	A249-L287 HydrophobicContact CB-CD1 3.69Å; A250-L287 HydrophobicContact CB-CD1 3.91Å; P271-L287 HydrophobicContact CB-CD2 4.09Å; I274-L287 HydrophobicContact CB-CD2 4.27Å; I274-L287 HydrophobicContact CG2-CD2 4Å; V275-L287 HydrophobicContact CG2-CB 3.97Å; V275-L287 HydrophobicContact CG2-CD2 3.64Å; V275-L287 HydrophobicContact CG2-CG 4.38Å; N283-L287 PolarHBondContact O-N 3.28Å; N283-L287 VanDerWaalsContact O-N 3.12Å; A284-L287 WeakPolarHBondContact O-CB 3.43Å; A284-L287 PolarHBondContact O-N 2.89Å; A285-L287 VanDerWaalsContact C-N 3.29Å; A285-L287 PolarHBondContact O-N 3.21Å; L287-M290 PolarHBondContact O-N 3Å; L287-E291 PolarHBondContact O-N 3.3Å
288	L	94.3	Very high	92.9	Very high	60 Å²	60	51.5 Å²	51.5	31%	0.314	27%	0.274	S	S	.	.	H	α-helix	trans	-65.3	-40.2	177	-69.5	172.6	0	0	0	112	A284 A285 M290 E291 E292	A284-L288 WeakPolarHBondContact O-CG 3.32Å; A284-L288 PolarHBondContact O-N 3.13Å; A285-L288 PolarHBondContact O-N 3.09Å; L288-M290 VanDerWaalsContact C-N 3.33Å; L288-M290 PolarHBondContact O-N 3.38Å; L288-E291 VanDerWaalsContact O-CB 3.28Å; L288-E291 WeakPolarHBondContact O-CB 3.48Å; L288-E291 PolarHBondContact O-N 3.31Å; L288-E292 WeakPolarHBondContact O-CG 3.4Å; L288-E292 PolarHBondContact O-N 2.89Å
289	R	95.5	Very high	93.2	Very high	104 Å²	104	53.7 Å²	53.7	39%	0.392	29%	0.29	S	S	.	.	H	α-helix	trans	-61.9	-41.7	173.3	-176.3	-179.4	175	-175.1	-0.5	111.7	A285 E291 E292 I293	A285-R289 WeakPolarHBondContact O-CB 3.42Å; A285-R289 PolarHBondContact O-N 3.37Å; R289-E291 VanDerWaalsContact C-N 3.29Å; R289-E291 PolarHBondContact O-N 2.71Å; R289-E292 PolarHBondContact O-N 3.33Å; R289-I293 HydrophobicContact CG-CD1 4.13Å; R289-I293 VanDerWaalsContact O-CG1 3.26Å; R289-I293 WeakPolarHBondContact O-CG1 3.1Å; R289-I293 PolarHBondContact O-N 3.49Å
290	M	96.3	Very high	93.5	Very high	13 Å²	13	51.8 Å²	51.8	6%	0.064	29%	0.289	C	S	.	.	H	α-helix	trans	-64.6	-36.2	175.6	-174.6	60.3	66.2	0	0	111.5	F233 V247 A250 D286 L287 L288 I293 L294 I482	F233-M290 HydrophobicContact CZ-SD 4.32Å; V247-M290 HydrophobicContact CG2-CE 4.48Å; V247-M290 HydrophobicContact CG2-CG 4.41Å; V247-M290 HydrophobicContact CG2-SD 3.94Å; A250-M290 HydrophobicContact CB-CB 3.93Å; A250-M290 HydrophobicContact CB-CG 3.67Å; D286-M290 WeakPolarHBondContact O-CB 3.47Å; D286-M290 PolarHBondContact O-N 2.89Å; L287-M290 PolarHBondContact O-N 3Å; L288-M290 VanDerWaalsContact C-N 3.33Å; L288-M290 PolarHBondContact O-N 3.38Å; M290-I293 PolarHBondContact O-N 3.33Å; M290-L294 VanDerWaalsContact O-CB 3.28Å; M290-L294 WeakPolarHBondContact O-CB 3.14Å; M290-L294 PolarHBondContact O-N 2.99Å; M290-I482 HydrophobicContact CE-CD1 3.8Å
291	E	95	Very high	93.8	Very high	26 Å²	26	53.7 Å²	53.7	12%	0.121	30%	0.299	C	S	.	.	H	α-helix	trans	-62	-47	174.2	-166.3	-166.9	140.3	0	0	111.8	A250 A254 K257 L287 L288 R289 I293 L294 D295	A250-E291 HydrophobicContact CB-CB 4.46Å; A254-E291 HydrophobicContact CB-CG 3.89Å; K257-E291 WeakPolarHBondContact CD-OE1 3.32Å; K257-E291 WeakPolarHBondContact CE-OE1 3.28Å; K257-E291 IonicContact NZ-OE1 3.04Å; K257-E291 PolarHBondContact NZ-OE1 3.47Å; K257-E291 IonicContact NZ-OE2 2.69Å; K257-E291 PolarHBondContact NZ-OE2 2.98Å; L287-E291 PolarHBondContact O-N 3.3Å; L288-E291 VanDerWaalsContact O-CB 3.28Å; L288-E291 WeakPolarHBondContact O-CB 3.48Å; L288-E291 PolarHBondContact O-N 3.31Å; R289-E291 VanDerWaalsContact C-N 3.29Å; R289-E291 PolarHBondContact O-N 2.71Å; E291-I293 PolarHBondContact O-N 2.87Å; E291-L294 WeakPolarHBondContact O-CB 3.22Å; E291-L294 PolarHBondContact O-N 3.3Å; E291-D295 WeakPolarHBondContact O-CB 3.33Å; E291-D295 PolarHBondContact O-N 3.01Å
292	E	95.7	Very high	94.3	Very high	129 Å²	129	53.3 Å²	53.3	60%	0.603	29%	0.288	S	S	*	.	H	α-helix	trans	-61.9	-41.3	176.5	-70.3	170.2	-172.7	0	0	112.2	L288 R289 L294 D295 S296	L288-E292 WeakPolarHBondContact O-CG 3.4Å; L288-E292 PolarHBondContact O-N 2.89Å; R289-E292 PolarHBondContact O-N 3.33Å; E292-L294 VanDerWaalsContact C-N 3.35Å; E292-D295 PolarHBondContact O-N 3.04Å; E292-S296 WeakPolarHBondContact O-CB 3.36Å; E292-S296 PolarHBondContact O-N 3.44Å; E292-S296 PolarHBondContact O-OG 3.44Å
293	I	96.5	Very high	94.6	Very high	49 Å²	49	56.7 Å²	56.7	25%	0.251	30%	0.303	S	S	.	.	H	α-helix	trans	-63.5	-43.8	175	-67.7	165.3	0	0	0	110.2	F233 R289 M290 E291 S296 K297	F233-I293 HydrophobicContact CE2-CG2 4.28Å; F233-I293 HydrophobicContact CZ-CG2 4.3Å; R289-I293 HydrophobicContact CG-CD1 4.13Å; R289-I293 VanDerWaalsContact O-CG1 3.26Å; R289-I293 WeakPolarHBondContact O-CG1 3.1Å; R289-I293 PolarHBondContact O-N 3.49Å; M290-I293 PolarHBondContact O-N 3.33Å; E291-I293 PolarHBondContact O-N 2.87Å; I293-S296 PolarHBondContact O-N 3.07Å; I293-K297 HydrophobicContact CG2-CG 4.13Å; I293-K297 WeakPolarHBondContact O-CB 3.47Å; I293-K297 VanDerWaalsContact O-CG 3.24Å; I293-K297 WeakPolarHBondContact O-CG 3.43Å; I293-K297 PolarHBondContact O-N 3.49Å
294	L	97.1	Very high	94.6	Very high	0 Å²	0	52.8 Å²	52.8	0%	0	28%	0.283	C	S	.	.	H	α-helix	trans	-60.3	-48.9	178.2	-178.8	150.6	0	0	0	110.8	L229 F233 M290 E291 E292 S296 K297 L298 L302	L229-L294 HydrophobicContact CD1-CD2 4.19Å; F233-L294 HydrophobicContact CB-CD1 4.5Å; F233-L294 HydrophobicContact CD2-CB 4.15Å; F233-L294 HydrophobicContact CD2-CD1 4.42Å; F233-L294 HydrophobicContact CD2-CG 3.99Å; F233-L294 HydrophobicContact CE2-CB 4.15Å; F233-L294 HydrophobicContact CE2-CG 4.5Å; F233-L294 HydrophobicContact CG-CD1 4.4Å; F233-L294 HydrophobicContact CG-CG 4.43Å; M290-L294 VanDerWaalsContact O-CB 3.28Å; M290-L294 WeakPolarHBondContact O-CB 3.14Å; M290-L294 PolarHBondContact O-N 2.99Å; E291-L294 WeakPolarHBondContact O-CB 3.22Å; E291-L294 PolarHBondContact O-N 3.3Å; E292-L294 VanDerWaalsContact C-N 3.35Å; L294-S296 PolarHBondContact O-N 3.43Å; L294-K297 PolarHBondContact O-N 2.96Å; L294-L298 HydrophobicContact CD2-CD1 3.72Å; L294-L298 HydrophobicContact CG-CD1 4.05Å; L294-L298 WeakPolarHBondContact O-CB 3.38Å; L294-L298 VanDerWaalsContact O-CG 3.3Å; L294-L298 WeakPolarHBondContact O-CG 3.43Å; L294-L298 PolarHBondContact O-N 2.8Å; L294-L302 HydrophobicContact CD2-CD2 3.77Å
295	D	95.9	Very high	94.7	Very high	42 Å²	42	52.6 Å²	52.6	23%	0.225	28%	0.28	C	S	.	.	H	α-helix	trans	-59.3	-47.1	178.4	-168.1	41.7	0	0	0	111.5	E291 E292 L298 S299 H300 L302	E291-D295 WeakPolarHBondContact O-CB 3.33Å; E291-D295 PolarHBondContact O-N 3.01Å; E292-D295 PolarHBondContact O-N 3.04Å; D295-L298 CarbonylContact O-C 3.6Å; D295-L298 PolarHBondContact O-N 3.38Å; D295-S299 PolarHBondContact O-N 3.38Å; D295-S299 VanDerWaalsContact O-N 3.12Å; D295-H300 VanDerWaalsContact CG-ND1 3.31Å; D295-H300 PolarHBondContact O-N 2.96Å; D295-H300 WeakPolarHBondContact OD1-CA 3.39Å; D295-H300 IonicContact OD1-ND1 3.45Å; D295-H300 IonicContact OD2-CE1 3.63Å; D295-H300 PolarHBondContact OD2-CE1 3.47Å; D295-H300 IonicContact OD2-CG 3.77Å; D295-H300 IonicContact OD2-ND1 2.7Å; D295-H300 PolarHBondContact OD2-ND1 3.39Å; D295-L302 VanDerWaalsContact OD1-CD1 3.3Å; D295-L302 WeakPolarHBondContact OD1-CD1 3.45Å; D295-L302 VanDerWaalsContact OD1-CG 3.3Å; D295-L302 WeakPolarHBondContact OD1-CG 3.43Å
296	S	96.8	Very high	94.7	Very high	72 Å²	72	50 Å²	50	50%	0.503	26%	0.256	S	S	.	.	H	α-helix	trans	-63.1	-45.9	178.1	-57.5	0	0	0	0	112.8	E292 I293 L294 L298 S299	E292-S296 WeakPolarHBondContact O-CB 3.36Å; E292-S296 PolarHBondContact O-N 3.44Å; E292-S296 PolarHBondContact O-OG 3.44Å; I293-S296 PolarHBondContact O-N 3.07Å; L294-S296 PolarHBondContact O-N 3.43Å; S296-L298 VanDerWaalsContact C-N 3.28Å; S296-L298 PolarHBondContact O-N 3.24Å; S296-S299 PolarHBondContact O-N 3.32Å; S296-S299 VanDerWaalsContact O-N 3.1Å
297	K	96.5	Very high	94.9	Very high	120 Å²	120	48.5 Å²	48.5	52%	0.522	25%	0.249	S	C	.	.	H	α-helix	trans	-72.3	-22.6	-179.2	-67	-64.4	-179.1	-171.2	0	112.8	F233 K236 V237 I293 L294 S299	F233-K297 HydrophobicContact CD2-CB 4.33Å; F233-K297 HydrophobicContact CE2-CB 4.08Å; F233-K297 HydrophobicContact CE2-CG 4.3Å; K236-K297 WeakPolarHBondContact CD-O 3.35Å; K236-K297 PolarHBondContact NZ-O 3.42Å; V237-K297 HydrophobicContact CG2-CB 4.02Å; V237-K297 HydrophobicContact CG2-CD 4.29Å; V237-K297 HydrophobicContact CG2-CG 3.89Å; I293-K297 HydrophobicContact CG2-CG 4.13Å; I293-K297 WeakPolarHBondContact O-CB 3.47Å; I293-K297 VanDerWaalsContact O-CG 3.24Å; I293-K297 WeakPolarHBondContact O-CG 3.43Å; I293-K297 PolarHBondContact O-N 3.49Å; L294-K297 PolarHBondContact O-N 2.96Å; K297-S299 VanDerWaalsContact C-N 3.34Å
298	L	95.6	Very high	94.9	Very high	1 Å²	1	49.1 Å²	49.1	1%	0.005	25%	0.252	C	S	.	.	T	Hydrogen-bonded Turn	trans	-91.9	8	171.4	-62.6	-177.9	0	0	0	113.1	L229 R232 K236 L294 D295 S296 H300 D301 L302	L229-L298 HydrophobicContact CB-CD1 4.23Å; L229-L298 HydrophobicContact CD2-CD1 3.64Å; L229-L298 HydrophobicContact CG-CD1 4.46Å; R232-L298 HydrophobicContact CB-CD2 3.85Å; K236-L298 HydrophobicContact CD-CD2 4.12Å; L294-L298 HydrophobicContact CD2-CD1 3.72Å; L294-L298 HydrophobicContact CG-CD1 4.05Å; L294-L298 WeakPolarHBondContact O-CB 3.38Å; L294-L298 VanDerWaalsContact O-CG 3.3Å; L294-L298 WeakPolarHBondContact O-CG 3.43Å; L294-L298 PolarHBondContact O-N 2.8Å; D295-L298 CarbonylContact O-C 3.6Å; D295-L298 PolarHBondContact O-N 3.38Å; S296-L298 VanDerWaalsContact C-N 3.28Å; S296-L298 PolarHBondContact O-N 3.24Å; L298-H300 VanDerWaalsContact C-N 3.29Å; L298-H300 PolarHBondContact O-N 2.87Å; L298-D301 WeakPolarHBondContact O-CB 3.33Å; L298-D301 PolarHBondContact O-N 3.17Å; L298-L302 HydrophobicContact CD1-CD2 4.36Å
299	S	93.9	Very high	95	Very high	87 Å²	87	47.3 Å²	47.3	61%	0.608	24%	0.243	S	C	*	.	T	Hydrogen-bonded Turn	trans	60.7	35.4	176.8	-49.7	0	0	0	0	113.4	D295 S296 K297 D301	D295-S299 PolarHBondContact O-N 3.38Å; D295-S299 VanDerWaalsContact O-N 3.12Å; S296-S299 PolarHBondContact O-N 3.32Å; S296-S299 VanDerWaalsContact O-N 3.1Å; K297-S299 VanDerWaalsContact C-N 3.34Å; S299-D301 PolarHBondContact O-N 3.25Å; S299-D301 VanDerWaalsContact O-N 3.11Å
300	H	92.1	Very high	95.1	Very high	129 Å²	129	42.4 Å²	42.4	60%	0.597	22%	0.224	S	C	*	.	T	Hydrogen-bonded Turn	trans	60.2	14.7	-176.6	-49.8	-74.7	0	0	0	115	D295 L298 L302	D295-H300 VanDerWaalsContact CG-ND1 3.31Å; D295-H300 PolarHBondContact O-N 2.96Å; D295-H300 WeakPolarHBondContact OD1-CA 3.39Å; D295-H300 IonicContact OD1-ND1 3.45Å; D295-H300 IonicContact OD2-CE1 3.63Å; D295-H300 PolarHBondContact OD2-CE1 3.47Å; D295-H300 IonicContact OD2-CG 3.77Å; D295-H300 IonicContact OD2-ND1 2.7Å; D295-H300 PolarHBondContact OD2-ND1 3.39Å; L298-H300 VanDerWaalsContact C-N 3.29Å; L298-H300 PolarHBondContact O-N 2.87Å; H300-L302 PolarHBondContact O-N 3.18Å
301	D	93.5	Very high	95.1	Very high	45 Å²	45	41.8 Å²	41.8	24%	0.241	22%	0.221	C	C	.	.			trans	-98.2	73.8	-178.3	172.8	37.8	0	0	0	110.1	Y178 R232 L298 S299	Y178-D301 WeakPolarHBondContact CE1-OD1 3.3Å; Y178-D301 WeakPolarHBondContact CE1-OD2 3.2Å; Y178-D301 VanDerWaalsContact OH-CG 3.31Å; Y178-D301 PolarHBondContact OH-OD1 3.39Å; Y178-D301 PolarHBondContact OH-OD2 2.76Å; R232-D301 IonicContact CZ-OD2 2.82Å; R232-D301 PolarHBondContact NH1-O 3.48Å; R232-D301 IonicContact NH1-OD2 2.95Å; R232-D301 IonicContact NH2-OD2 2.76Å; R232-D301 PolarHBondContact NH2-OD2 3.45Å; L298-D301 WeakPolarHBondContact O-CB 3.33Å; L298-D301 PolarHBondContact O-N 3.17Å; S299-D301 PolarHBondContact O-N 3.25Å; S299-D301 VanDerWaalsContact O-N 3.11Å
302	L	92.7	Very high	95.1	Very high	26 Å²	26	43 Å²	43	14%	0.136	23%	0.227	C	C	.	.			trans	-86.9	-17.8	-177.7	-58.2	-176.7	0	0	0	113.7	L229 A254 L258 L294 D295 L298 H300 G304	L229-L302 HydrophobicContact CD1-CB 4.49Å; L229-L302 HydrophobicContact CD1-CD2 4.04Å; L229-L302 HydrophobicContact CD2-CB 4.43Å; L229-L302 HydrophobicContact CD2-CD2 4.02Å; A254-L302 HydrophobicContact CB-CD1 4.17Å; L258-L302 HydrophobicContact CD2-CB 4.32Å; L294-L302 HydrophobicContact CD2-CD2 3.77Å; D295-L302 VanDerWaalsContact OD1-CD1 3.3Å; D295-L302 WeakPolarHBondContact OD1-CD1 3.45Å; D295-L302 VanDerWaalsContact OD1-CG 3.3Å; D295-L302 WeakPolarHBondContact OD1-CG 3.43Å; L298-L302 HydrophobicContact CD1-CD2 4.36Å; H300-L302 PolarHBondContact O-N 3.18Å; L302-G304 VanDerWaalsContact C-N 3.32Å; L302-G304 PolarHBondContact O-N 3.43Å
303	D	91.8	Very high	95.1	Very high	84 Å²	84	37 Å²	37	45%	0.449	20%	0.199	S	C	.	.	S	Bend	trans	-95.9	50.1	-175.3	-160.1	39.3	0	0	0	112.6	K225 L258	K225-D303 WeakPolarHBondContact CE-OD1 3.36Å; K225-D303 IonicContact NZ-OD1 3.29Å; K225-D303 PolarHBondContact NZ-OD1 3Å; L258-D303 HydrophobicContact CD2-CB 3.94Å
304	G	92.1	Very high	95	Very high	2 Å²	2	34.7 Å²	34.7	2%	0.021	19%	0.187	C	C	.	.			trans	-75.3	142.4	-172.4	0	0	0	0	0	115.1	L302 N306	L302-G304 VanDerWaalsContact C-N 3.32Å; L302-G304 PolarHBondContact O-N 3.43Å; G304-N306 PolarHBondContact O-N 3.25Å; G304-N306 PolarHBondContact O-ND2 2.9Å
305	V	94.9	Very high	94.8	Very high	14 Å²	14	34.9 Å²	34.9	9%	0.085	19%	0.188	C	C	.	.			trans	-63.9	130.7	177.1	176.3	0	0	0	0	110.4	L171 K174 Y178 D309 F310	L171-V305 HydrophobicContact CD2-CG1 3.85Å; L171-V305 HydrophobicContact CD2-CG2 4.06Å; K174-V305 HydrophobicContact CB-CB 4.34Å; K174-V305 HydrophobicContact CB-CG2 3.82Å; K174-V305 HydrophobicContact CD-CG2 3.95Å; Y178-V305 WeakPolarHBondContact CB-O 3.37Å; Y178-V305 HydrophobicContact CD2-CB 3.86Å; Y178-V305 HydrophobicContact CD2-CG2 4.16Å; Y178-V305 HydrophobicContact CE2-CB 4.48Å; Y178-V305 HydrophobicContact CE2-CG2 4.29Å; Y178-V305 HydrophobicContact CG-CB 4.37Å; V305-D309 VanDerWaalsContact CA-OD2 3.3Å; V305-D309 WeakPolarHBondContact CA-OD2 3.38Å; V305-F310 HydrophobicContact CG1-CE2 3.92Å; V305-F310 HydrophobicContact CG1-CZ 4.36Å
306	N	95	Very high	94.6	Very high	9 Å²	9	35 Å²	35	5%	0.048	19%	0.188	C	C	.	.			trans	-138.7	-179.7	-179	65.6	61.3	0	0	0	111.8	K225 N228 G304 F308 D309 F310	K225-N306 WeakPolarHBondContact CG-ND2 3.37Å; N228-N306 HydrophobicContact CB-CB 4.37Å; G304-N306 PolarHBondContact O-N 3.25Å; G304-N306 PolarHBondContact O-ND2 2.9Å; N306-F308 PolarHBondContact O-N 2.89Å; N306-F308 WeakPolarHBondContact OD1-CA 3.36Å; N306-F308 WeakPolarHBondContact OD1-CB 3.33Å; N306-F308 PolarHBondContact OD1-N 3.07Å; N306-D309 PolarHBondContact N-OD2 3.47Å; N306-D309 PolarHBondContact O-N 2.9Å; N306-F310 WeakPolarHBondContact O-CD2 3.41Å
307	A	96.4	Very high	94.5	Very high	6 Å²	6	31.7 Å²	31.7	5%	0.05	17%	0.165	C	C	.	.	H	α-helix	trans	-62.8	-24.7	-177.4	0	0	0	0	0	113.5	L311 M390 P404 L407	A307-L311 WeakPolarHBondContact O-CB 3.45Å; A307-L311 PolarHBondContact O-N 2.97Å; A307-M390 HydrophobicContact CB-CE 3.7Å; A307-M390 HydrophobicContact CB-SD 3.97Å; A307-P404 HydrophobicContact CB-CB 4.19Å; A307-P404 WeakPolarHBondContact CB-O 3.46Å; A307-L407 HydrophobicContact CB-CB 4.2Å; A307-L407 HydrophobicContact CB-CD2 3.86Å; A307-L407 HydrophobicContact CB-CG 4.2Å
308	F	96.2	Very high	94.2	Very high	14 Å²	14	26.1 Å²	26.1	6%	0.061	14%	0.141	C	C	.	.	H	α-helix	trans	-69.6	-33.4	177.1	-175.3	-94.1	0	0	0	112.2	T220 E221 C224 N306 F310 L311 Q312	T220-F308 HydrophobicContact CG2-CD2 3.89Å; T220-F308 HydrophobicContact CG2-CE2 3.82Å; E221-F308 HydrophobicContact CB-CD1 3.81Å; E221-F308 HydrophobicContact CB-CE1 3.47Å; E221-F308 VanDerWaalsContact CB-CE1 3.47Å; E221-F308 HydrophobicContact CB-CZ 4.07Å; E221-F308 HydrophobicContact CG-CD1 3.83Å; E221-F308 HydrophobicContact CG-CE1 3.81Å; C224-F308 HydrophobicContact CB-CB 3.83Å; C224-F308 HydrophobicContact CB-CG 4.46Å; N306-F308 PolarHBondContact O-N 2.89Å; N306-F308 WeakPolarHBondContact OD1-CA 3.36Å; N306-F308 WeakPolarHBondContact OD1-CB 3.33Å; N306-F308 PolarHBondContact OD1-N 3.07Å; F308-F310 PolarHBondContact O-N 3.21Å; F308-L311 HydrophobicContact CD2-CD2 4.29Å; F308-L311 WeakPolarHBondContact O-CB 3.33Å; F308-L311 PolarHBondContact O-N 3.33Å; F308-Q312 HydrophobicContact CE1-CB 4.5Å; F308-Q312 WeakPolarHBondContact O-CB 3.36Å; F308-Q312 PolarHBondContact O-N 3.38Å
309	D	96.2	Very high	93.9	Very high	22 Å²	22	27 Å²	27	12%	0.118	15%	0.147	C	C	.	.	H	α-helix	trans	-65.1	-40.9	178.7	-57.5	-51.6	0	0	0	111.8	L171 V305 N306 L313	L171-D309 HydrophobicContact CD1-CB 4.2Å; L171-D309 HydrophobicContact CD2-CB 3.9Å; V305-D309 VanDerWaalsContact CA-OD2 3.3Å; V305-D309 WeakPolarHBondContact CA-OD2 3.38Å; N306-D309 PolarHBondContact N-OD2 3.47Å; N306-D309 PolarHBondContact O-N 2.9Å; D309-L313 PolarHBondContact O-N 2.95Å; D309-L313 VanDerWaalsContact O-N 3.09Å
310	F	97.4	Very high	93.8	Very high	0 Å²	0	27.7 Å²	27.7	0%	0	14%	0.139	C	C	.	.	H	α-helix	trans	-65	-44.2	171.6	-66.6	-76	0	0	0	111.4	L168 L171 L172 E175 V305 N306 F308 Q312 L313 F314 P404 V405 A408	L168-F310 HydrophobicContact CD1-CD1 4.34Å; L168-F310 HydrophobicContact CD1-CE1 4.46Å; L171-F310 HydrophobicContact CB-CD1 3.99Å; L171-F310 HydrophobicContact CB-CE1 3.28Å; L171-F310 HydrophobicContact CB-CE2 4.38Å; L171-F310 HydrophobicContact CB-CZ 3.54Å; L171-F310 HydrophobicContact CD1-CD1 4.03Å; L171-F310 HydrophobicContact CD1-CE1 4.2Å; L171-F310 HydrophobicContact CD1-CG 4.47Å; L171-F310 HydrophobicContact CG-CE1 4.37Å; L172-F310 HydrophobicContact CD2-CE1 4.11Å; L172-F310 HydrophobicContact CG-CE1 4.3Å; E175-F310 HydrophobicContact CB-CZ 4.17Å; E175-F310 HydrophobicContact CG-CE2 4.23Å; E175-F310 HydrophobicContact CG-CZ 4.25Å; V305-F310 HydrophobicContact CG1-CE2 3.92Å; V305-F310 HydrophobicContact CG1-CZ 4.36Å; N306-F310 WeakPolarHBondContact O-CD2 3.41Å; F308-F310 PolarHBondContact O-N 3.21Å; F310-Q312 VanDerWaalsContact C-N 3.33Å; F310-Q312 PolarHBondContact O-N 2.92Å; F310-L313 PolarHBondContact O-N 3.43Å; F310-F314 HydrophobicContact CB-CE2 4.08Å; F310-F314 WeakPolarHBondContact O-CD2 3.46Å; F310-F314 WeakPolarHBondContact O-CG 3.48Å; F310-F314 PolarHBondContact O-N 2.88Å; F310-P404 HydrophobicContact CD2-CB 4.11Å; F310-P404 HydrophobicContact CE2-CB 3.96Å; F310-V405 HydrophobicContact CD1-CB 4.32Å; F310-V405 HydrophobicContact CD1-CG1 4.43Å; F310-V405 HydrophobicContact CD1-CG2 3.48Å; F310-V405 VanDerWaalsContact CD1-CG2 3.48Å; F310-V405 HydrophobicContact CD2-CG2 3.96Å; F310-V405 HydrophobicContact CE1-CB 4.44Å; F310-V405 HydrophobicContact CE1-CG2 3.2Å; F310-V405 HydrophobicContact CE2-CG2 3.72Å; F310-V405 HydrophobicContact CG-CB 4.42Å; F310-V405 HydrophobicContact CG-CG2 3.84Å; F310-V405 HydrophobicContact CZ-CG2 3.32Å; F310-A408 HydrophobicContact CB-CB 3.73Å
311	L	96.1	Very high	93.6	Very high	0 Å²	0	21.6 Å²	21.6	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-58.7	-45.5	177.6	179.4	64.8	0	0	0	111.1	A307 F308 F314 I315 L386 M390 A408 I411 L412	A307-L311 WeakPolarHBondContact O-CB 3.45Å; A307-L311 PolarHBondContact O-N 2.97Å; F308-L311 HydrophobicContact CD2-CD2 4.29Å; F308-L311 WeakPolarHBondContact O-CB 3.33Å; F308-L311 PolarHBondContact O-N 3.33Å; L311-F314 PolarHBondContact O-N 3.32Å; L311-I315 HydrophobicContact CD1-CD1 4.06Å; L311-I315 HydrophobicContact CD1-CG1 4.26Å; L311-I315 HydrophobicContact CD2-CD1 4.37Å; L311-I315 HydrophobicContact CG-CD1 3.75Å; L311-I315 HydrophobicContact CG-CG1 4.37Å; L311-I315 WeakPolarHBondContact O-CG1 3.22Å; L311-I315 PolarHBondContact O-N 3.5Å; L311-L386 HydrophobicContact CD1-CB 4.42Å; L311-L386 HydrophobicContact CD1-CD1 4.36Å; L311-L386 HydrophobicContact CD1-CD2 4.41Å; L311-L386 HydrophobicContact CD2-CB 4.15Å; L311-M390 HydrophobicContact CB-CE 4.07Å; L311-M390 HydrophobicContact CD2-CB 4.34Å; L311-M390 HydrophobicContact CD2-CE 3.79Å; L311-M390 HydrophobicContact CG-CE 4.49Å; L311-A408 HydrophobicContact CB-CB 4.12Å; L311-I411 HydrophobicContact CD1-CG2 4.44Å; L311-L412 HydrophobicContact CD1-CD2 3.77Å; L311-L412 HydrophobicContact CD1-CG 3.96Å
312	Q	94.5	Very high	93.2	Very high	53 Å²	53	20.1 Å²	20.1	25%	0.248	10%	0.102	C	C	.	.	H	α-helix	trans	-60.3	-47.5	177.2	176.6	167.4	-3	0	0	111.3	F308 F310 F314 I315 D316 Y383	F308-Q312 HydrophobicContact CE1-CB 4.5Å; F308-Q312 WeakPolarHBondContact O-CB 3.36Å; F308-Q312 PolarHBondContact O-N 3.38Å; F310-Q312 VanDerWaalsContact C-N 3.33Å; F310-Q312 PolarHBondContact O-N 2.92Å; Q312-F314 VanDerWaalsContact C-N 3.29Å; Q312-F314 PolarHBondContact O-N 3.3Å; Q312-I315 PolarHBondContact O-N 2.96Å; Q312-D316 PolarHBondContact O-N 3.48Å; Q312-Y383 WeakPolarHBondContact CG-OH 3.36Å
313	L	95.6	Very high	92.9	Very high	3 Å²	3	21.3 Å²	21.3	2%	0.016	11%	0.109	C	C	.	.	H	α-helix	trans	-56.7	-43.3	176.4	-177.3	155.4	0	0	0	111.9	L163 R167 L168 L171 D309 F310 D316 C317	L163-L313 HydrophobicContact CD1-CD2 3.26Å; L163-L313 HydrophobicContact CG-CD2 4.01Å; R167-L313 HydrophobicContact CB-CD1 3.81Å; R167-L313 HydrophobicContact CG-CD1 3.7Å; L168-L313 HydrophobicContact CB-CD1 4.08Å; L171-L313 HydrophobicContact CD1-CB 4.42Å; L171-L313 HydrophobicContact CD1-CD1 3.84Å; D309-L313 PolarHBondContact O-N 2.95Å; D309-L313 VanDerWaalsContact O-N 3.09Å; F310-L313 PolarHBondContact O-N 3.43Å; L313-D316 PolarHBondContact O-N 3.03Å; L313-C317 PolarHBondContact O-N 3.09Å
314	F	95.3	Very high	92.6	Very high	0 Å²	0	20.1 Å²	20.1	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-72	-36.9	178.6	-59.9	-32.6	0	0	0	112.8	L163 L168 F310 L311 Q312 D316 C317 V318 V405 A408 L409 L412 L423	L163-F314 HydrophobicContact CD1-CD1 3.93Å; L163-F314 HydrophobicContact CD1-CE1 4.28Å; L168-F314 HydrophobicContact CD1-CE1 4.12Å; L168-F314 HydrophobicContact CD1-CZ 4.3Å; F310-F314 HydrophobicContact CB-CE2 4.08Å; F310-F314 WeakPolarHBondContact O-CD2 3.46Å; F310-F314 WeakPolarHBondContact O-CG 3.48Å; F310-F314 PolarHBondContact O-N 2.88Å; L311-F314 PolarHBondContact O-N 3.32Å; Q312-F314 VanDerWaalsContact C-N 3.29Å; Q312-F314 PolarHBondContact O-N 3.3Å; F314-D316 VanDerWaalsContact C-N 3.34Å; F314-C317 WeakPolarHBondContact O-CB 3.38Å; F314-C317 PolarHBondContact O-N 3.38Å; F314-V318 VanDerWaalsContact O-CG2 3.31Å; F314-V318 WeakPolarHBondContact O-CG2 3.33Å; F314-V318 PolarHBondContact O-N 3.36Å; F314-V405 HydrophobicContact CE2-CG1 4.38Å; F314-V405 HydrophobicContact CZ-CG1 4.17Å; F314-A408 HydrophobicContact CD2-CB 4.19Å; F314-A408 HydrophobicContact CE2-CB 4.09Å; F314-L409 HydrophobicContact CD2-CD2 4.11Å; F314-L409 HydrophobicContact CE2-CD2 3.7Å; F314-L409 HydrophobicContact CE2-CG 3.93Å; F314-L409 HydrophobicContact CZ-CD2 4.11Å; F314-L409 HydrophobicContact CZ-CG 4.46Å; F314-L412 HydrophobicContact CB-CD1 3.48Å; F314-L412 VanDerWaalsContact CB-CD1 3.48Å; F314-L412 HydrophobicContact CD2-CD1 3.62Å; F314-L412 HydrophobicContact CG-CD1 3.89Å; F314-L423 HydrophobicContact CD1-CD1 4.26Å; F314-L423 HydrophobicContact CD1-CD2 3.7Å; F314-L423 HydrophobicContact CD1-CG 4.44Å; F314-L423 HydrophobicContact CD2-CD2 4.5Å; F314-L423 HydrophobicContact CE1-CD1 3.78Å; F314-L423 HydrophobicContact CE1-CD2 3.77Å; F314-L423 HydrophobicContact CE1-CG 4.04Å; F314-L423 HydrophobicContact CG-CD2 4.1Å; F314-L423 HydrophobicContact CZ-CD1 4.47Å; F314-L423 HydrophobicContact CZ-CD2 4.2Å; F314-L423 HydrophobicContact CZ-CG 4.37Å
315	I	92.2	Very high	92.1	Very high	4 Å²	4	22.8 Å²	22.8	2%	0.021	12%	0.115	C	C	.	.	H	α-helix	trans	-63.2	-43.3	173.7	-66.5	164.4	0	0	0	110.1	L311 Q312 C317 V318 T319 Y383 L386	L311-I315 HydrophobicContact CD1-CD1 4.06Å; L311-I315 HydrophobicContact CD1-CG1 4.26Å; L311-I315 HydrophobicContact CD2-CD1 4.37Å; L311-I315 HydrophobicContact CG-CD1 3.75Å; L311-I315 HydrophobicContact CG-CG1 4.37Å; L311-I315 WeakPolarHBondContact O-CG1 3.22Å; L311-I315 PolarHBondContact O-N 3.5Å; Q312-I315 PolarHBondContact O-N 2.96Å; I315-C317 VanDerWaalsContact C-N 3.25Å; I315-C317 PolarHBondContact O-N 3.38Å; I315-V318 CarbonylContact O-C 3.58Å; I315-V318 PolarHBondContact O-N 3.06Å; I315-V318 VanDerWaalsContact O-N 3.09Å; I315-T319 HydrophobicContact CG2-CG2 4.02Å; I315-T319 VanDerWaalsContact O-CG2 3.31Å; I315-T319 WeakPolarHBondContact O-CG2 3.3Å; I315-T319 PolarHBondContact O-N 2.97Å; I315-T319 PolarHBondContact O-OG1 2.6Å; I315-Y383 HydrophobicContact CB-CE2 4.12Å; I315-Y383 HydrophobicContact CD1-CD1 4.11Å; I315-Y383 HydrophobicContact CD1-CE1 3.89Å; I315-Y383 HydrophobicContact CD1-CE2 4.37Å; I315-Y383 HydrophobicContact CD1-CG 4.42Å; I315-Y383 HydrophobicContact CG2-CD2 3.68Å; I315-Y383 HydrophobicContact CG2-CE2 3.24Å; I315-L386 HydrophobicContact CD1-CB 4.28Å; I315-L386 HydrophobicContact CD1-CD1 3.5Å; I315-L386 HydrophobicContact CG1-CD1 3.5Å
316	D	92.6	Very high	91.3	Very high	43 Å²	43	24.5 Å²	24.5	23%	0.23	12%	0.121	C	C	.	.	H	α-helix	trans	-57.2	-42.4	176.8	-63.6	-21.1	0	0	0	110.5	R167 Q312 L313 F314 T319 K320	R167-D316 IonicContact NH1-OD2 3.82Å; R167-D316 PolarHBondContact NH1-OD2 3.08Å; Q312-D316 PolarHBondContact O-N 3.48Å; L313-D316 PolarHBondContact O-N 3.03Å; F314-D316 VanDerWaalsContact C-N 3.34Å; D316-T319 PolarHBondContact O-N 2.85Å; D316-T319 PolarHBondContact O-OG1 3.03Å; D316-K320 WeakPolarHBondContact O-CG 3.49Å; D316-K320 PolarHBondContact O-N 3.22Å; D316-K320 VanDerWaalsContact O-N 3.14Å
317	C	93.2	Very high	90.7	Very high	3 Å²	3	28.5 Å²	28.5	2%	0.02	14%	0.143	C	C	.	.	H	α-helix	trans	-61.8	-47.2	173.3	-178.2	0	0	0	0	112.7	C158 K159 L163 L313 F314 I315 T319 K320 S321	C158-C317 VanDerWaalsContact SG-SG 3.68Å; K159-C317 PolarHBondContact O-SG 3.46Å; L163-C317 HydrophobicContact CD1-CB 3.85Å; L313-C317 PolarHBondContact O-N 3.09Å; F314-C317 WeakPolarHBondContact O-CB 3.38Å; F314-C317 PolarHBondContact O-N 3.38Å; I315-C317 VanDerWaalsContact C-N 3.25Å; I315-C317 PolarHBondContact O-N 3.38Å; C317-T319 VanDerWaalsContact C-N 3.33Å; C317-T319 PolarHBondContact O-N 3Å; C317-K320 PolarHBondContact O-N 3.13Å; C317-S321 WeakPolarHBondContact O-CB 3.46Å; C317-S321 PolarHBondContact O-N 3.14Å
318	V	91	Very high	90	Very high	3 Å²	3	33.2 Å²	33.2	2%	0.018	16%	0.164	C	C	.	.	H	α-helix	trans	-62.2	-39.7	178.6	168.7	0	0	0	0	111.7	I156 C158 F314 I315 S321 K322 W378 I417	I156-V318 HydrophobicContact CG2-CG1 3.23Å; C158-V318 HydrophobicContact CB-CG2 3.84Å; F314-V318 VanDerWaalsContact O-CG2 3.31Å; F314-V318 WeakPolarHBondContact O-CG2 3.33Å; F314-V318 PolarHBondContact O-N 3.36Å; I315-V318 CarbonylContact O-C 3.58Å; I315-V318 PolarHBondContact O-N 3.06Å; I315-V318 VanDerWaalsContact O-N 3.09Å; V318-S321 WeakPolarHBondContact O-CB 3.41Å; V318-S321 PolarHBondContact O-N 2.68Å; V318-K322 PolarHBondContact O-N 2.89Å; V318-W378 HydrophobicContact CG1-CH2 4.33Å; V318-I417 HydrophobicContact CG2-CD1 4.45Å; V318-I417 HydrophobicContact CG2-CG2 3.99Å
319	T	89.4	Confident	89.1	Confident	19 Å²	19	38.7 Å²	38.7	12%	0.117	19%	0.193	C	C	.	.	H	α-helix	trans	-65.1	-45.2	177.4	60.7	0	0	0	0	112.1	I315 D316 C317 S321 K322 D323 W378 K379	I315-T319 HydrophobicContact CG2-CG2 4.02Å; I315-T319 VanDerWaalsContact O-CG2 3.31Å; I315-T319 WeakPolarHBondContact O-CG2 3.3Å; I315-T319 PolarHBondContact O-N 2.97Å; I315-T319 PolarHBondContact O-OG1 2.6Å; D316-T319 PolarHBondContact O-N 2.85Å; D316-T319 PolarHBondContact O-OG1 3.03Å; C317-T319 VanDerWaalsContact C-N 3.33Å; C317-T319 PolarHBondContact O-N 3Å; T319-S321 VanDerWaalsContact C-N 3.32Å; T319-S321 PolarHBondContact O-N 3.41Å; T319-K322 PolarHBondContact O-N 3.48Å; T319-D323 PolarHBondContact O-N 3.33Å; T319-W378 HydrophobicContact CG2-CH2 3.61Å; T319-W378 HydrophobicContact CG2-CZ2 3.9Å; T319-K379 HydrophobicContact CG2-CD 4.15Å; T319-K379 HydrophobicContact CG2-CG 4.1Å
320	K	90.6	Very high	88.3	Confident	102 Å²	102	41.2 Å²	41.2	44%	0.443	21%	0.206	S	C	.	.	H	α-helix	trans	-60.4	-42.3	174.3	-68.4	171.7	-175.2	177.2	0	111.8	L162 D316 C317 K322 D323 I324	L162-K320 HydrophobicContact CB-CB 4.5Å; L162-K320 HydrophobicContact CD1-CB 4.11Å; D316-K320 WeakPolarHBondContact O-CG 3.49Å; D316-K320 PolarHBondContact O-N 3.22Å; D316-K320 VanDerWaalsContact O-N 3.14Å; C317-K320 PolarHBondContact O-N 3.13Å; K320-K322 VanDerWaalsContact C-N 3.35Å; K320-K322 PolarHBondContact O-N 3.41Å; K320-D323 PolarHBondContact O-N 3.41Å; K320-I324 WeakPolarHBondContact O-CG1 3.3Å; K320-I324 PolarHBondContact O-N 2.75Å
321	S	88.9	Confident	87.2	Confident	1 Å²	1	45.7 Å²	45.7	1%	0.007	23%	0.23	C	C	.	.	H	α-helix	trans	-59.3	-46.2	178.1	-177.4	0	0	0	0	111.7	V157 K159 L162 C317 V318 T319 I324 M325	V157-S321 VanDerWaalsContact O-CB 3.27Å; V157-S321 WeakPolarHBondContact O-CB 3.47Å; V157-S321 PolarHBondContact O-OG 2.91Å; K159-S321 WeakPolarHBondContact CD-OG 3.48Å; K159-S321 WeakPolarHBondContact CG-OG 3.45Å; L162-S321 VanDerWaalsContact CD1-CA 3.41Å; C317-S321 WeakPolarHBondContact O-CB 3.46Å; C317-S321 PolarHBondContact O-N 3.14Å; V318-S321 WeakPolarHBondContact O-CB 3.41Å; V318-S321 PolarHBondContact O-N 2.68Å; T319-S321 VanDerWaalsContact C-N 3.32Å; T319-S321 PolarHBondContact O-N 3.41Å; S321-I324 PolarHBondContact O-N 3.38Å; S321-M325 WeakPolarHBondContact O-CG 3.47Å; S321-M325 PolarHBondContact O-N 3.4Å
322	K	85.2	Confident	86.1	Confident	15 Å²	15	49.4 Å²	49.4	7%	0.065	25%	0.253	C	S	.	.	H	α-helix	trans	-66.6	-45	179	179.2	165.3	164.4	-174.3	0	112.5	V318 T319 K320 I324 M325 E326 W378	V318-K322 PolarHBondContact O-N 2.89Å; T319-K322 PolarHBondContact O-N 3.48Å; K320-K322 VanDerWaalsContact C-N 3.35Å; K320-K322 PolarHBondContact O-N 3.41Å; K322-I324 PolarHBondContact O-N 3.15Å; K322-M325 PolarHBondContact O-N 3.45Å; K322-M325 VanDerWaalsContact O-N 3.1Å; K322-E326 VanDerWaalsContact CE-CD 3.44Å; K322-E326 WeakPolarHBondContact CE-OE1 3.37Å; K322-E326 HydrophobicContact CG-CG 4.49Å; K322-E326 IonicContact NZ-OE1 2.72Å; K322-E326 PolarHBondContact NZ-OE1 3.09Å; K322-E326 PolarHBondContact O-N 2.79Å; K322-W378 HydrophobicContact CB-CH2 4.28Å; K322-W378 HydrophobicContact CB-CZ2 3.95Å; K322-W378 HydrophobicContact CD-CD2 3.9Å; K322-W378 VanDerWaalsContact CD-CE2 3.47Å; K322-W378 HydrophobicContact CD-CE3 4.34Å; K322-W378 HydrophobicContact CD-CG 4.43Å; K322-W378 HydrophobicContact CD-CH2 4.04Å; K322-W378 HydrophobicContact CD-CZ2 3.57Å; K322-W378 HydrophobicContact CD-CZ3 4.39Å; K322-W378 HydrophobicContact CG-CZ2 4.09Å
323	D	85.6	Confident	84.8	Confident	50 Å²	50	48.2 Å²	48.2	27%	0.267	26%	0.255	S	S	.	.	H	α-helix	trans	-57.6	-36.5	178.5	-65.4	-11.7	0	0	0	111.1	T319 K320 N327 K379	T319-D323 PolarHBondContact O-N 3.33Å; K320-D323 PolarHBondContact O-N 3.41Å; D323-N327 PolarHBondContact O-N 3.33Å; D323-N327 VanDerWaalsContact O-N 3.15Å; D323-N327 PolarHBondContact O-ND2 2.93Å; D323-K379 VanDerWaalsContact CG-NZ 3.28Å; D323-K379 VanDerWaalsContact OD1-CE 3.29Å; D323-K379 WeakPolarHBondContact OD1-CE 3.28Å; D323-K379 IonicContact OD1-NZ 3.43Å; D323-K379 PolarHBondContact OD1-NZ 3.45Å; D323-K379 IonicContact OD2-NZ 3.85Å; D323-K379 PolarHBondContact OD2-NZ 2.7Å
324	I	86.4	Confident	83.3	Confident	60 Å²	60	52.2 Å²	52.2	31%	0.308	28%	0.275	S	S	.	.	H	α-helix	trans	-67.3	-46.5	175.5	-67.8	165.9	0	0	0	111.7	L162 K320 S321 K322 E326 N327 E328	L162-I324 HydrophobicContact CD1-CD1 3.74Å; L162-I324 HydrophobicContact CD2-CD1 3.78Å; L162-I324 HydrophobicContact CG-CD1 4.42Å; K320-I324 WeakPolarHBondContact O-CG1 3.3Å; K320-I324 PolarHBondContact O-N 2.75Å; S321-I324 PolarHBondContact O-N 3.38Å; K322-I324 PolarHBondContact O-N 3.15Å; I324-E326 VanDerWaalsContact C-N 3.3Å; I324-E326 PolarHBondContact O-N 3.42Å; I324-N327 PolarHBondContact O-N 3.04Å; I324-E328 HydrophobicContact CG2-CG 4.42Å; I324-E328 WeakPolarHBondContact CG2-OE1 3.39Å; I324-E328 WeakPolarHBondContact O-CG 3.23Å; I324-E328 PolarHBondContact O-N 3.27Å
325	M	82.3	Confident	81.3	Confident	58 Å²	58	57.5 Å²	57.5	29%	0.286	30%	0.303	S	S	.	.	H	α-helix	trans	-62.9	-37.4	-179.9	-65	-171	-30.5	0	0	112.3	S321 K322 E328 L329	S321-M325 WeakPolarHBondContact O-CG 3.47Å; S321-M325 PolarHBondContact O-N 3.4Å; K322-M325 PolarHBondContact O-N 3.45Å; K322-M325 VanDerWaalsContact O-N 3.1Å; M325-E328 PolarHBondContact O-N 3.18Å; M325-L329 WeakPolarHBondContact O-CB 3.2Å; M325-L329 PolarHBondContact O-N 3.35Å
326	E	78.3	Confident	80.1	Confident	49 Å²	49	60.4 Å²	60.4	23%	0.229	32%	0.318	C	S	.	.	H	α-helix	trans	-68.5	-41.2	177.2	-74.6	173	161.2	0	0	111.3	K322 I324 E328 L329 I330	K322-E326 VanDerWaalsContact CE-CD 3.44Å; K322-E326 WeakPolarHBondContact CE-OE1 3.37Å; K322-E326 HydrophobicContact CG-CG 4.49Å; K322-E326 IonicContact NZ-OE1 2.72Å; K322-E326 PolarHBondContact NZ-OE1 3.09Å; K322-E326 PolarHBondContact O-N 2.79Å; I324-E326 VanDerWaalsContact C-N 3.3Å; I324-E326 PolarHBondContact O-N 3.42Å; E326-E328 PolarHBondContact O-N 2.99Å; E326-L329 PolarHBondContact O-N 3.16Å; E326-I330 WeakPolarHBondContact O-CD1 3.22Å; E326-I330 VanDerWaalsContact O-CG1 3.24Å; E326-I330 WeakPolarHBondContact O-CG1 3.34Å; E326-I330 PolarHBondContact O-N 3.36Å
327	N	81.6	Confident	78.5	Confident	94 Å²	94	62.7 Å²	62.7	50%	0.503	33%	0.331	S	S	.	.	H	α-helix	trans	-63.4	-40.3	174	-70.2	-31.3	0	0	0	112.4	D323 I324 I330 N331	D323-N327 PolarHBondContact O-N 3.33Å; D323-N327 VanDerWaalsContact O-N 3.15Å; D323-N327 PolarHBondContact O-ND2 2.93Å; I324-N327 PolarHBondContact O-N 3.04Å; N327-I330 PolarHBondContact O-N 3.41Å; N327-N331 WeakPolarHBondContact O-CB 3.3Å; N327-N331 PolarHBondContact O-N 3.15Å; N327-N331 PolarHBondContact O-ND2 3.45Å
328	E	81.6	Confident	76.7	Confident	105 Å²	105	65.3 Å²	65.3	49%	0.491	35%	0.349	S	S	.	.	H	α-helix	trans	-62	-45.1	174.4	-74.3	171.2	179.8	0	0	111.3	I324 M325 E326 I330 N331 V332	I324-E328 HydrophobicContact CG2-CG 4.42Å; I324-E328 WeakPolarHBondContact CG2-OE1 3.39Å; I324-E328 WeakPolarHBondContact O-CG 3.23Å; I324-E328 PolarHBondContact O-N 3.27Å; M325-E328 PolarHBondContact O-N 3.18Å; E326-E328 PolarHBondContact O-N 2.99Å; E328-I330 PolarHBondContact O-N 3.32Å; E328-N331 PolarHBondContact O-N 3.36Å; E328-V332 VanDerWaalsContact O-CG2 3.29Å; E328-V332 WeakPolarHBondContact O-CG2 3.45Å; E328-V332 PolarHBondContact O-N 3.02Å
329	L	78.2	Confident	74.9	Confident	128 Å²	128	71.1 Å²	71.1	67%	0.67	37%	0.371	S	S	*	.	H	α-helix	trans	-63.9	-40.9	178.2	-174	66.1	0	0	0	112.2	M325 E326 V332 G333	M325-L329 WeakPolarHBondContact O-CB 3.2Å; M325-L329 PolarHBondContact O-N 3.35Å; E326-L329 PolarHBondContact O-N 3.16Å; L329-V332 PolarHBondContact O-N 3.44Å; L329-G333 PolarHBondContact O-N 3.41Å
330	I	78.8	Confident	73.4	Confident	75 Å²	75	74.8 Å²	74.8	39%	0.385	39%	0.39	S	S	.	.	H	α-helix	trans	-64.3	-45.2	175.7	-68	164.5	0	0	0	110.4	E326 N327 E328 V332 G333 L334	E326-I330 WeakPolarHBondContact O-CD1 3.22Å; E326-I330 VanDerWaalsContact O-CG1 3.24Å; E326-I330 WeakPolarHBondContact O-CG1 3.34Å; E326-I330 PolarHBondContact O-N 3.36Å; N327-I330 PolarHBondContact O-N 3.41Å; E328-I330 PolarHBondContact O-N 3.32Å; I330-V332 VanDerWaalsContact C-N 3.34Å; I330-V332 PolarHBondContact O-N 3.19Å; I330-G333 CarbonylContact O-C 3.6Å; I330-G333 PolarHBondContact O-N 2.96Å; I330-L334 HydrophobicContact CG2-CD1 4.05Å; I330-L334 HydrophobicContact CG2-CG 4.4Å; I330-L334 WeakPolarHBondContact O-CG 3.3Å; I330-L334 PolarHBondContact O-N 2.95Å
331	N	74.8	Confident	71.4	Confident	94 Å²	94	75.3 Å²	75.3	50%	0.503	40%	0.397	S	S	.	.	H	α-helix	trans	-64.2	-38.2	178.6	-72.1	-17.4	0	0	0	112.3	N327 E328 L334 N335	N327-N331 WeakPolarHBondContact O-CB 3.3Å; N327-N331 PolarHBondContact O-N 3.15Å; N327-N331 PolarHBondContact O-ND2 3.45Å; E328-N331 PolarHBondContact O-N 3.36Å; N331-L334 PolarHBondContact O-N 3.19Å; N331-N335 WeakPolarHBondContact O-CB 3.5Å; N331-N335 PolarHBondContact O-N 2.95Å; N331-N335 PolarHBondContact O-ND2 3.15Å
332	V	73	Confident	69.5	Low	79 Å²	79	82.2 Å²	82.2	48%	0.479	43%	0.429	S	S	.	.	H	α-helix	trans	-65.2	-44.2	172.7	173	0	0	0	0	110.5	E328 L329 I330 L334 N335 I336	E328-V332 VanDerWaalsContact O-CG2 3.29Å; E328-V332 WeakPolarHBondContact O-CG2 3.45Å; E328-V332 PolarHBondContact O-N 3.02Å; L329-V332 PolarHBondContact O-N 3.44Å; I330-V332 VanDerWaalsContact C-N 3.34Å; I330-V332 PolarHBondContact O-N 3.19Å; V332-L334 VanDerWaalsContact C-N 3.32Å; V332-L334 PolarHBondContact O-N 3.38Å; V332-N335 PolarHBondContact O-N 3.46Å; V332-I336 HydrophobicContact CG1-CD1 3.88Å; V332-I336 HydrophobicContact CG1-CG1 4.4Å; V332-I336 WeakPolarHBondContact O-CA 3.34Å; V332-I336 WeakPolarHBondContact O-CB 3.06Å; V332-I336 WeakPolarHBondContact O-CG1 3.33Å; V332-I336 PolarHBondContact O-N 3.25Å
333	G	66.2	Low	67.9	Low	28 Å²	28	85.5 Å²	85.5	29%	0.289	45%	0.454	S	S	.	.	H	α-helix	trans	-62.2	-32.7	176.4	0	0	0	0	0	114.3	L329 I330 I336 D337	L329-G333 PolarHBondContact O-N 3.41Å; I330-G333 CarbonylContact O-C 3.6Å; I330-G333 PolarHBondContact O-N 2.96Å; G333-I336 VanDerWaalsContact O-CA 3.26Å; G333-I336 WeakPolarHBondContact O-CA 3.44Å; G333-I336 WeakPolarHBondContact O-CB 3.45Å; G333-D337 PolarHBondContact O-N 2.95Å; G333-D337 VanDerWaalsContact O-N 3.16Å
334	L	63.5	Low	65.8	Low	86 Å²	86	89.5 Å²	89.5	45%	0.45	48%	0.475	S	S	.	.	H	α-helix	trans	-76.5	-36.3	173.1	-69.2	172.9	0	0	0	112.3	I330 N331 V332 D337 S338	I330-L334 HydrophobicContact CG2-CD1 4.05Å; I330-L334 HydrophobicContact CG2-CG 4.4Å; I330-L334 WeakPolarHBondContact O-CG 3.3Å; I330-L334 PolarHBondContact O-N 2.95Å; N331-L334 PolarHBondContact O-N 3.19Å; V332-L334 VanDerWaalsContact C-N 3.32Å; V332-L334 PolarHBondContact O-N 3.38Å; L334-D337 PolarHBondContact O-N 3.11Å; L334-S338 VanDerWaalsContact O-CB 3.3Å; L334-S338 WeakPolarHBondContact O-CB 3.47Å; L334-S338 PolarHBondContact O-N 3.08Å
335	N	53.8	Low	63.6	Low	111 Å²	111	92.4 Å²	92.4	59%	0.594	50%	0.496	S	S	*	.	H	α-helix	trans	-64.7	-54.8	174.9	-78.6	-24.9	0	0	0	111.1	N331 V332 S338 Y339	N331-N335 WeakPolarHBondContact O-CB 3.5Å; N331-N335 PolarHBondContact O-N 2.95Å; N331-N335 PolarHBondContact O-ND2 3.15Å; V332-N335 PolarHBondContact O-N 3.46Å; N335-S338 WeakPolarHBondContact O-CB 3.3Å; N335-S338 PolarHBondContact O-N 3.48Å; N335-Y339 VanDerWaalsContact C-CD1 3.4Å; N335-Y339 WeakPolarHBondContact O-CD1 3.49Å; N335-Y339 PolarHBondContact O-N 2.8Å
336	I	67.8	Low	61.4	Low	65 Å²	65	98.4 Å²	98.4	33%	0.333	52%	0.523	S	S	.	.	H	α-helix		23.1	-108.9	123.1	-16.8	151.6	0	0	0	120.2	V332 G333 S338 Y339 L340	V332-I336 HydrophobicContact CG1-CD1 3.88Å; V332-I336 HydrophobicContact CG1-CG1 4.4Å; V332-I336 WeakPolarHBondContact O-CA 3.34Å; V332-I336 WeakPolarHBondContact O-CB 3.06Å; V332-I336 WeakPolarHBondContact O-CG1 3.33Å; V332-I336 PolarHBondContact O-N 3.25Å; G333-I336 VanDerWaalsContact O-CA 3.26Å; G333-I336 WeakPolarHBondContact O-CA 3.44Å; G333-I336 WeakPolarHBondContact O-CB 3.45Å; I336-S338 PolarHBondContact O-N 3.08Å; I336-Y339 VanDerWaalsContact C-CE1 3.45Å; I336-Y339 HydrophobicContact CB-CD1 4.28Å; I336-Y339 HydrophobicContact CB-CE1 3.32Å; I336-Y339 VanDerWaalsContact CB-CZ 3.5Å; I336-Y339 WeakPolarHBondContact CB-OH 3.46Å; I336-Y339 HydrophobicContact CG1-CD1 4.4Å; I336-Y339 HydrophobicContact CG1-CE1 3.24Å; I336-Y339 WeakPolarHBondContact CG1-OH 3.43Å; I336-Y339 HydrophobicContact CG2-CE1 3.77Å; I336-Y339 HydrophobicContact CG2-CE2 4.19Å; I336-Y339 WeakPolarHBondContact CG2-OH 3.4Å; I336-Y339 VanDerWaalsContact N-CD1 3.27Å; I336-Y339 WeakPolarHBondContact O-CD1 3.49Å; I336-Y339 WeakPolarHBondContact O-CD2 3.44Å; I336-Y339 WeakPolarHBondContact O-CE1 3.39Å; I336-Y339 WeakPolarHBondContact O-CE2 3.41Å; I336-Y339 PolarHBondContact O-N 3.35Å; I336-L340 PolarHBondContact O-N 2.92Å
337	D	57.4	Low	59.3	Low	92 Å²	92	105.2 Å²	105.2	49%	0.492	55%	0.552	S	S	.	*	H	α-helix	trans	-63.2	-29	179.7	-64.5	-26.7	0	0	0	112.7	G333 L334 L340 L341	G333-D337 PolarHBondContact O-N 2.95Å; G333-D337 VanDerWaalsContact O-N 3.16Å; L334-D337 PolarHBondContact O-N 3.11Å; D337-L340 PolarHBondContact O-N 3.27Å; D337-L341 WeakPolarHBondContact O-CB 3.18Å; D337-L341 WeakPolarHBondContact O-CG 3.08Å; D337-L341 PolarHBondContact O-N 3.04Å
338	S	55.7	Low	56.8	Low	57 Å²	57	108.7 Å²	108.7	40%	0.399	57%	0.567	S	S	.	*	H	α-helix	trans	-63.9	-45.2	176.2	-168	0	0	0	0	111.8	L334 N335 I336 L340 L341 E342	L334-S338 VanDerWaalsContact O-CB 3.3Å; L334-S338 WeakPolarHBondContact O-CB 3.47Å; L334-S338 PolarHBondContact O-N 3.08Å; N335-S338 WeakPolarHBondContact O-CB 3.3Å; N335-S338 PolarHBondContact O-N 3.48Å; I336-S338 PolarHBondContact O-N 3.08Å; S338-L340 VanDerWaalsContact C-N 3.28Å; S338-L340 PolarHBondContact O-N 3.23Å; S338-L341 PolarHBondContact O-N 2.92Å; S338-E342 WeakPolarHBondContact O-CG 3.48Å; S338-E342 PolarHBondContact O-N 3.19Å
339	Y	54.2	Low	54.3	Low	125 Å²	125	109.3 Å²	109.3	49%	0.49	58%	0.578	S	S	.	*	H	α-helix	trans	-69.1	-30.7	176.5	66.6	-115.3	0	0	0	111.9	N335 I336 E342 S343	N335-Y339 VanDerWaalsContact C-CD1 3.4Å; N335-Y339 WeakPolarHBondContact O-CD1 3.49Å; N335-Y339 PolarHBondContact O-N 2.8Å; I336-Y339 VanDerWaalsContact C-CE1 3.45Å; I336-Y339 HydrophobicContact CB-CD1 4.28Å; I336-Y339 HydrophobicContact CB-CE1 3.32Å; I336-Y339 VanDerWaalsContact CB-CZ 3.5Å; I336-Y339 WeakPolarHBondContact CB-OH 3.46Å; I336-Y339 HydrophobicContact CG1-CD1 4.4Å; I336-Y339 HydrophobicContact CG1-CE1 3.24Å; I336-Y339 WeakPolarHBondContact CG1-OH 3.43Å; I336-Y339 HydrophobicContact CG2-CE1 3.77Å; I336-Y339 HydrophobicContact CG2-CE2 4.19Å; I336-Y339 WeakPolarHBondContact CG2-OH 3.4Å; I336-Y339 VanDerWaalsContact N-CD1 3.27Å; I336-Y339 WeakPolarHBondContact O-CD1 3.49Å; I336-Y339 WeakPolarHBondContact O-CD2 3.44Å; I336-Y339 WeakPolarHBondContact O-CE1 3.39Å; I336-Y339 WeakPolarHBondContact O-CE2 3.41Å; I336-Y339 PolarHBondContact O-N 3.35Å; Y339-E342 PolarHBondContact O-N 3.05Å; Y339-S343 PolarHBondContact O-N 3.49Å; Y339-S343 PolarHBondContact O-OG 3.27Å
340	L	56.6	Low	52.1	Low	97 Å²	97	111.3 Å²	111.3	51%	0.508	58%	0.584	S	S	.	*	H	α-helix	trans	-75.4	-29.8	-179.4	-155.5	133.5	0	0	0	111.3	I336 D337 S338 S343	I336-L340 PolarHBondContact O-N 2.92Å; D337-L340 PolarHBondContact O-N 3.27Å; S338-L340 VanDerWaalsContact C-N 3.28Å; S338-L340 PolarHBondContact O-N 3.23Å; L340-S343 PolarHBondContact O-OG 3.05Å
341	L	50.4	Low	49.8	Very low	113 Å²	113	113.2 Å²	113.2	59%	0.592	60%	0.6	S	S	*	*	H	α-helix	trans	-77.3	-32.9	170.7	-75.1	168.5	0	0	0	113	D337 S338 S343	D337-L341 WeakPolarHBondContact O-CB 3.18Å; D337-L341 WeakPolarHBondContact O-CG 3.08Å; D337-L341 PolarHBondContact O-N 3.04Å; S338-L341 PolarHBondContact O-N 2.92Å; L341-S343 VanDerWaalsContact C-N 3.27Å; L341-S343 PolarHBondContact O-N 2.94Å
342	E	48.3	Very low	47.9	Very low	146 Å²	146	115.3 Å²	115.3	68%	0.682	61%	0.611	S	S	*	*	H	α-helix	trans	-69.7	-23.6	175.3	-79.9	179.6	175.8	0	0	112.8	S338 Y339 D344	S338-E342 WeakPolarHBondContact O-CG 3.48Å; S338-E342 PolarHBondContact O-N 3.19Å; Y339-E342 PolarHBondContact O-N 3.05Å; E342-D344 VanDerWaalsContact C-N 3.31Å; E342-D344 PolarHBondContact O-N 3.22Å
343	S	50.7	Low	45.9	Very low	84 Å²	84	118.6 Å²	118.6	59%	0.587	63%	0.625	S	S	*	*	T	Hydrogen-bonded Turn	trans	-75.2	-9.4	178.1	47.7	0	0	0	0	115.8	Y339 L340 L341	Y339-S343 PolarHBondContact O-N 3.49Å; Y339-S343 PolarHBondContact O-OG 3.27Å; L340-S343 PolarHBondContact O-OG 3.05Å; L341-S343 VanDerWaalsContact C-N 3.27Å; L341-S343 PolarHBondContact O-N 2.94Å
344	D	42.2	Very low	44.7	Very low	133 Å²	133	125.3 Å²	125.3	71%	0.711	65%	0.653	S	S	*	*	T	Hydrogen-bonded Turn	trans	-105.2	14.7	-176.8	-77	-16.3	0	0	0	114.7	E342 E346	E342-D344 VanDerWaalsContact C-N 3.31Å; E342-D344 PolarHBondContact O-N 3.22Å; D344-E346 VanDerWaalsContact C-N 3.35Å; D344-E346 PolarHBondContact O-N 2.99Å
345	V	40.4	Very low	43.4	Very low	122 Å²	122	127.6 Å²	127.6	74%	0.739	67%	0.671	S	S	*	*			trans	-88.4	9.3	-177.3	-175.8	0	0	0	0	114.3
346	E	36.5	Very low	42.7	Very low	184 Å²	184	126.3 Å²	126.3	86%	0.86	67%	0.671	S	S	*	*	S	Bend	trans	-115.3	76.4	170.3	-76.8	-168.7	164.5	0	0	112.5	D344	D344-E346 VanDerWaalsContact C-N 3.35Å; D344-E346 PolarHBondContact O-N 2.99Å
347	K	33.5	Very low	41.5	Very low	192 Å²	192	128.2 Å²	128.2	84%	0.835	69%	0.69	S	S	*	*	S	Bend	trans	165.2	145.3	131.7	-90.8	157.9	-174.9	171.7	0	114.2
348	M	29.3	Very low	40.8	Very low	166 Å²	166	128.5 Å²	128.5	82%	0.818	69%	0.694	S	S	*	*			trans	76	91.6	160.3	-102.2	87.8	-178.5	0	0	118.5
349	T	29	Very low	40.2	Very low	119 Å²	119	133 Å²	133	73%	0.73	71%	0.709	S	S	*	*				-0.9	140.1	123.2	50.3	0	0	0	0	118
350	E	31.7	Very low	39.7	Very low	169 Å²	169	134.4 Å²	134.4	79%	0.79	72%	0.718	S	S	*	*			trans	107	100.1	154.3	-69.1	173.1	-174.7	0	0	118.7
351	T	31.7	Very low	39.2	Very low	116 Å²	116	132.3 Å²	132.3	71%	0.712	71%	0.712	S	S	*	*			trans	73.2	116.3	135.9	61.7	0	0	0	0	120
352	N	33.2	Very low	39	Very low	137 Å²	137	129.9 Å²	129.9	73%	0.733	70%	0.699	S	S	*	*			trans	64.7	106.1	137.6	-57.9	-13.5	0	0	0	117.3
353	N	32.6	Very low	39.1	Very low	148 Å²	148	129.7 Å²	129.7	79%	0.791	70%	0.698	S	S	*	*				-176.5	110	106.2	-82.7	-24.8	0	0	0	110.4	T355	N353-T355 PolarHBondContact O-N 3.44Å; N353-T355 VanDerWaalsContact O-N 3.15Å
354	I	39.5	Very low	39.2	Very low	169 Å²	169	129.7 Å²	129.7	87%	0.867	69%	0.694	S	S	*	*			trans	-71.7	95.6	167.1	-62.2	165.8	0	0	0	106.6
355	T	37.3	Very low	39.5	Very low	134 Å²	134	131.2 Å²	131.2	82%	0.822	69%	0.69	S	S	*	*			trans	177.6	52.1	155.4	42.8	0	0	0	0	112.9	N353	N353-T355 PolarHBondContact O-N 3.44Å; N353-T355 VanDerWaalsContact O-N 3.15Å
356	S	38.7	Very low	40	Very low	85 Å²	85	132 Å²	132	59%	0.594	68%	0.683	S	S	*	*			trans	-145.2	5.3	169.1	63.7	0	0	0	0	115.8	V358	S356-V358 PolarHBondContact O-N 2.86Å
357	S	42.6	Very low	40.9	Very low	105 Å²	105	126.2 Å²	126.2	73%	0.734	66%	0.664	S	S	*	*	H	α-helix	trans	-74.6	-6.1	178.3	51.2	0	0	0	0	114.7
358	V	42.9	Very low	42.1	Very low	97 Å²	97	120.4 Å²	120.4	59%	0.588	64%	0.641	S	S	*	*	H	α-helix	trans	-84.8	-33.6	179.8	-179.3	0	0	0	0	112.1	S356 S361 D362	S356-V358 PolarHBondContact O-N 2.86Å; V358-S361 PolarHBondContact O-N 3.36Å; V358-S361 PolarHBondContact O-OG 3.27Å; V358-D362 PolarHBondContact O-N 2.98Å
359	E	42.7	Very low	43.5	Very low	153 Å²	153	116.8 Å²	116.8	72%	0.715	63%	0.628	S	S	*	*	H	α-helix	trans	-72.9	-37.7	-171.9	-69.4	-174.5	158.2	0	0	114.3	S361 D362 E363	E359-S361 PolarHBondContact O-N 3.18Å; E359-D362 PolarHBondContact O-N 3.05Å; E359-E363 PolarHBondContact O-N 3.11Å
360	K	43.7	Very low	45	Very low	153 Å²	153	113.9 Å²	113.9	67%	0.665	61%	0.611	S	S	*	*	H	α-helix	trans	-67.1	-35	177.6	-79	-175.5	176.8	-179.1	0	112.7	D362 E363 V364	K360-D362 VanDerWaalsContact C-N 3.31Å; K360-E363 PolarHBondContact O-N 3.1Å; K360-V364 WeakPolarHBondContact O-CG2 3.48Å; K360-V364 PolarHBondContact O-N 3.45Å
361	S	45.9	Very low	46.2	Very low	54 Å²	54	107.1 Å²	107.1	38%	0.378	58%	0.584	S	S	.	*	H	α-helix	trans	-69.6	-32	176.2	78	0	0	0	0	112.1	V358 E359 R365	V358-S361 PolarHBondContact O-N 3.36Å; V358-S361 PolarHBondContact O-OG 3.27Å; E359-S361 PolarHBondContact O-N 3.18Å; S361-R365 WeakPolarHBondContact O-CB 3.33Å; S361-R365 PolarHBondContact O-N 2.87Å
362	D	46.8	Very low	47.3	Very low	62 Å²	62	109.6 Å²	109.6	33%	0.332	58%	0.58	S	S	.	*	H	α-helix	trans	-74.5	-34.7	176.8	-81.7	-15.6	0	0	0	112.3	V358 E359 K360 R365 K366	V358-D362 PolarHBondContact O-N 2.98Å; E359-D362 PolarHBondContact O-N 3.05Å; K360-D362 VanDerWaalsContact C-N 3.31Å; D362-R365 PolarHBondContact O-N 3.32Å; D362-K366 VanDerWaalsContact O-CB 3.23Å; D362-K366 WeakPolarHBondContact O-CB 3.07Å; D362-K366 WeakPolarHBondContact O-CD 3.27Å; D362-K366 WeakPolarHBondContact O-CG 3.42Å; D362-K366 PolarHBondContact O-N 3.36Å
363	E	50.8	Low	48.5	Very low	141 Å²	141	108.8 Å²	108.8	66%	0.659	57%	0.572	S	S	*	*	H	α-helix	trans	-70.1	-41.1	177	-164.1	163.5	-157.7	0	0	112.2	E359 K360 K366 S367	E359-E363 PolarHBondContact O-N 3.11Å; K360-E363 PolarHBondContact O-N 3.1Å; E363-K366 PolarHBondContact O-N 2.97Å; E363-S367 WeakPolarHBondContact O-CB 3.32Å; E363-S367 PolarHBondContact O-N 3.46Å; E363-S367 PolarHBondContact O-OG 2.79Å
364	V	51.3	Low	49.8	Very low	84 Å²	84	110 Å²	110	51%	0.509	57%	0.565	S	S	.	*	H	α-helix	trans	-65.6	-39.2	171.3	178.2	0	0	0	0	111.2	K360 S367 L368	K360-V364 WeakPolarHBondContact O-CG2 3.48Å; K360-V364 PolarHBondContact O-N 3.45Å; V364-S367 WeakPolarHBondContact CA-OG 3.36Å; V364-S367 PolarHBondContact O-N 2.82Å; V364-S367 PolarHBondContact O-OG 3.3Å; V364-L368 VanDerWaalsContact O-CB 3.3Å; V364-L368 WeakPolarHBondContact O-CB 3.38Å; V364-L368 PolarHBondContact O-N 3.38Å
365	R	48.5	Very low	50.9	Low	165 Å²	165	103.7 Å²	103.7	62%	0.623	53%	0.533	S	S	*	.	H	α-helix	trans	-64.3	-43.2	172.2	-95.6	-174.3	176.5	118.3	0.3	112.1	S361 D362 L368 V369	S361-R365 WeakPolarHBondContact O-CB 3.33Å; S361-R365 PolarHBondContact O-N 2.87Å; D362-R365 PolarHBondContact O-N 3.32Å; R365-L368 PolarHBondContact O-N 3.18Å; R365-V369 WeakPolarHBondContact O-CB 3.43Å; R365-V369 WeakPolarHBondContact O-CG2 3.46Å; R365-V369 PolarHBondContact O-N 3.29Å
366	K	50.9	Low	52.4	Low	138 Å²	138	104.3 Å²	104.3	60%	0.6	53%	0.525	S	S	*	.	H	α-helix	trans	-64.9	-40.2	177.6	-75.9	165.9	-173.3	170.7	0	110.8	D362 E363 T370	D362-K366 VanDerWaalsContact O-CB 3.23Å; D362-K366 WeakPolarHBondContact O-CB 3.07Å; D362-K366 WeakPolarHBondContact O-CD 3.27Å; D362-K366 WeakPolarHBondContact O-CG 3.42Å; D362-K366 PolarHBondContact O-N 3.36Å; E363-K366 PolarHBondContact O-N 2.97Å; K366-T370 WeakPolarHBondContact O-CB 3.49Å; K366-T370 WeakPolarHBondContact O-CG2 3.44Å; K366-T370 PolarHBondContact O-N 2.93Å; K366-T370 PolarHBondContact O-OG1 3.4Å
367	S	56.9	Low	54.3	Low	63 Å²	63	104.6 Å²	104.6	44%	0.441	52%	0.519	S	S	.	.	H	α-helix	trans	-65.9	-40.9	175	75	0	0	0	0	111.4	E363 V364 T370 A371	E363-S367 WeakPolarHBondContact O-CB 3.32Å; E363-S367 PolarHBondContact O-N 3.46Å; E363-S367 PolarHBondContact O-OG 2.79Å; V364-S367 WeakPolarHBondContact CA-OG 3.36Å; V364-S367 PolarHBondContact O-N 2.82Å; V364-S367 PolarHBondContact O-OG 3.3Å; S367-T370 WeakPolarHBondContact CA-OG1 3.41Å; S367-T370 PolarHBondContact O-N 2.72Å; S367-T370 PolarHBondContact O-OG1 2.8Å; S367-A371 WeakPolarHBondContact O-CB 3.17Å; S367-A371 PolarHBondContact O-N 3.33Å
368	L	58	Low	55.9	Low	71 Å²	71	100.1 Å²	100.1	37%	0.372	49%	0.487	S	S	.	.	H	α-helix	trans	-67.2	-41.9	175.8	-174.9	67.9	0	0	0	112.6	V364 R365 A371 R372	V364-L368 VanDerWaalsContact O-CB 3.3Å; V364-L368 WeakPolarHBondContact O-CB 3.38Å; V364-L368 PolarHBondContact O-N 3.38Å; R365-L368 PolarHBondContact O-N 3.18Å; L368-A371 PolarHBondContact O-N 2.75Å; L368-R372 WeakPolarHBondContact O-CB 3.23Å; L368-R372 WeakPolarHBondContact O-CG 3.49Å; L368-R372 PolarHBondContact O-N 2.97Å
369	V	59.5	Low	57.7	Low	89 Å²	89	98.5 Å²	98.5	54%	0.539	47%	0.472	S	S	.	.	H	α-helix	trans	-65.5	-43.7	176.4	170.5	0	0	0	0	110.3	R365 R372 Q373	R365-V369 WeakPolarHBondContact O-CB 3.43Å; R365-V369 WeakPolarHBondContact O-CG2 3.46Å; R365-V369 PolarHBondContact O-N 3.29Å; V369-R372 PolarHBondContact O-N 2.75Å; V369-Q373 WeakPolarHBondContact O-CB 3.48Å; V369-Q373 PolarHBondContact O-N 3.44Å
370	T	59.1	Low	59.7	Low	59 Å²	59	93.5 Å²	93.5	36%	0.362	45%	0.451	S	S	.	.	H	α-helix	trans	-68.8	-35.2	177	54.6	0	0	0	0	112.4	K366 S367 Q373 R374	K366-T370 WeakPolarHBondContact O-CB 3.49Å; K366-T370 WeakPolarHBondContact O-CG2 3.44Å; K366-T370 PolarHBondContact O-N 2.93Å; K366-T370 PolarHBondContact O-OG1 3.4Å; S367-T370 WeakPolarHBondContact CA-OG1 3.41Å; S367-T370 PolarHBondContact O-N 2.72Å; S367-T370 PolarHBondContact O-OG1 2.8Å; T370-Q373 PolarHBondContact O-N 2.68Å; T370-R374 VanDerWaalsContact O-CG 3.31Å; T370-R374 WeakPolarHBondContact O-CG 3.44Å; T370-R374 PolarHBondContact O-N 3.4Å
371	A	57.4	Low	61.5	Low	27 Å²	27	90.2 Å²	90.2	22%	0.223	44%	0.441	C	S	.	.	H	α-helix	trans	-60.9	-54.9	170.3	0	0	0	0	0	110.5	S367 L368 Q373 R374 D375	S367-A371 WeakPolarHBondContact O-CB 3.17Å; S367-A371 PolarHBondContact O-N 3.33Å; L368-A371 PolarHBondContact O-N 2.75Å; A371-Q373 VanDerWaalsContact C-N 3.25Å; A371-Q373 PolarHBondContact O-N 3.5Å; A371-R374 CarbonylContact O-C 3.5Å; A371-R374 WeakPolarHBondContact O-CA 3.45Å; A371-R374 WeakPolarHBondContact O-CB 3.42Å; A371-R374 PolarHBondContact O-N 3.2Å; A371-D375 PolarHBondContact O-N 3.3Å
372	R	55.7	Low	63.3	Low	168 Å²	168	88 Å²	88	63%	0.634	43%	0.425	S	S	*	.	H	α-helix	trans	-57.5	-35.2	176.9	-75.8	-178	177.4	-174.9	0.1	113.7	L368 V369 D375 F376	L368-R372 WeakPolarHBondContact O-CB 3.23Å; L368-R372 WeakPolarHBondContact O-CG 3.49Å; L368-R372 PolarHBondContact O-N 2.97Å; V369-R372 PolarHBondContact O-N 2.75Å; R372-D375 WeakPolarHBondContact CA-OD2 3.3Å; R372-D375 WeakPolarHBondContact O-CB 3.48Å; R372-D375 PolarHBondContact O-N 3.17Å; R372-F376 PolarHBondContact O-N 3.36Å
373	Q	57	Low	65.2	Low	119 Å²	119	88.4 Å²	88.4	56%	0.556	42%	0.422	S	S	*	.	H	α-helix	trans	-69.6	-39.6	175.4	-172.3	174.6	-3.6	0	0	111.9	V369 T370 A371 D375 N377	V369-Q373 WeakPolarHBondContact O-CB 3.48Å; V369-Q373 PolarHBondContact O-N 3.44Å; T370-Q373 PolarHBondContact O-N 2.68Å; A371-Q373 VanDerWaalsContact C-N 3.25Å; A371-Q373 PolarHBondContact O-N 3.5Å; Q373-D375 PolarHBondContact O-N 3.3Å; Q373-N377 WeakPolarHBondContact O-CB 3.39Å; Q373-N377 PolarHBondContact O-N 2.93Å; Q373-N377 PolarHBondContact O-ND2 2.82Å
374	R	60.1	Low	66.9	Low	175 Å²	175	88.3 Å²	88.3	66%	0.66	42%	0.42	S	S	*	.	H	α-helix	trans	-63.6	-33.1	168.9	-70.1	173.5	-173.2	151.6	2.3	111.1	T370 A371 N377 W378	T370-R374 VanDerWaalsContact O-CG 3.31Å; T370-R374 WeakPolarHBondContact O-CG 3.44Å; T370-R374 PolarHBondContact O-N 3.4Å; A371-R374 CarbonylContact O-C 3.5Å; A371-R374 WeakPolarHBondContact O-CA 3.45Å; A371-R374 WeakPolarHBondContact O-CB 3.42Å; A371-R374 PolarHBondContact O-N 3.2Å; R374-N377 PolarHBondContact O-N 2.88Å; R374-W378 PolarHBondContact O-N 2.98Å
375	D	63.2	Low	68.6	Low	35 Å²	35	86.6 Å²	86.6	19%	0.187	40%	0.404	C	S	.	.	H	α-helix	trans	-64.8	-52.1	179.5	-60.3	-20.5	0	0	0	112.1	A371 R372 Q373 N377 W378 K379	A371-D375 PolarHBondContact O-N 3.3Å; R372-D375 WeakPolarHBondContact CA-OD2 3.3Å; R372-D375 WeakPolarHBondContact O-CB 3.48Å; R372-D375 PolarHBondContact O-N 3.17Å; Q373-D375 PolarHBondContact O-N 3.3Å; D375-N377 PolarHBondContact O-N 3.42Å; D375-W378 VanDerWaalsContact CA-CD1 3.48Å; D375-W378 PolarHBondContact O-N 3.45Å; D375-W378 PolarHBondContact O-NE1 3.17Å; D375-K379 PolarHBondContact O-N 2.98Å; D375-K379 VanDerWaalsContact O-N 3.16Å
376	F	68.1	Low	70.7	Confident	147 Å²	147	78.8 Å²	78.8	65%	0.645	38%	0.375	S	S	*	.	H	α-helix	trans	-58.7	-38.8	175.1	-173.5	-98.8	0	0	0	112	R372 T380	R372-F376 PolarHBondContact O-N 3.36Å; F376-T380 WeakPolarHBondContact O-CB 3.34Å; F376-T380 PolarHBondContact O-N 3.39Å; F376-T380 PolarHBondContact O-OG1 3.46Å
377	N	79.2	Confident	72.7	Confident	91 Å²	91	72.2 Å²	72.2	49%	0.487	35%	0.347	S	S	.	.	H	α-helix	trans	-67.9	-41.3	178.9	-74.1	-13.7	0	0	0	112.6	Q373 R374 D375 L381	Q373-N377 WeakPolarHBondContact O-CB 3.39Å; Q373-N377 PolarHBondContact O-N 2.93Å; Q373-N377 PolarHBondContact O-ND2 2.82Å; R374-N377 PolarHBondContact O-N 2.88Å; D375-N377 PolarHBondContact O-N 3.42Å; N377-L381 WeakPolarHBondContact O-CB 3.3Å; N377-L381 PolarHBondContact O-N 3.2Å
378	W	77.3	Confident	74.3	Confident	12 Å²	12	71.3 Å²	71.3	5%	0.045	34%	0.338	C	S	.	.	H	α-helix	trans	-69.1	-42.9	179.4	90.8	-100.2	0	0	0	111.6	V318 T319 K322 R374 D375 T380 L381 V382	V318-W378 HydrophobicContact CG1-CH2 4.33Å; T319-W378 HydrophobicContact CG2-CH2 3.61Å; T319-W378 HydrophobicContact CG2-CZ2 3.9Å; K322-W378 HydrophobicContact CB-CH2 4.28Å; K322-W378 HydrophobicContact CB-CZ2 3.95Å; K322-W378 HydrophobicContact CD-CD2 3.9Å; K322-W378 VanDerWaalsContact CD-CE2 3.47Å; K322-W378 HydrophobicContact CD-CE3 4.34Å; K322-W378 HydrophobicContact CD-CG 4.43Å; K322-W378 HydrophobicContact CD-CH2 4.04Å; K322-W378 HydrophobicContact CD-CZ2 3.57Å; K322-W378 HydrophobicContact CD-CZ3 4.39Å; K322-W378 HydrophobicContact CG-CZ2 4.09Å; R374-W378 PolarHBondContact O-N 2.98Å; D375-W378 VanDerWaalsContact CA-CD1 3.48Å; D375-W378 PolarHBondContact O-N 3.45Å; D375-W378 PolarHBondContact O-NE1 3.17Å; W378-T380 VanDerWaalsContact C-N 3.26Å; W378-T380 PolarHBondContact O-N 2.8Å; W378-L381 PolarHBondContact O-N 2.86Å; W378-L381 VanDerWaalsContact O-N 3.13Å; W378-V382 HydrophobicContact CE3-CB 3.97Å; W378-V382 HydrophobicContact CE3-CG2 3.53Å; W378-V382 HydrophobicContact CZ3-CB 4.07Å; W378-V382 HydrophobicContact CZ3-CG1 4.27Å; W378-V382 HydrophobicContact CZ3-CG2 3.92Å; W378-V382 WeakPolarHBondContact O-CB 2.94Å; W378-V382 WeakPolarHBondContact O-CG2 3.36Å; W378-V382 PolarHBondContact O-N 3.17Å
379	K	80.4	Confident	76	Confident	63 Å²	63	68 Å²	68	27%	0.274	32%	0.321	S	S	.	.	H	α-helix	trans	-57.1	-47.8	179.7	-71.3	-172.1	-178	-179.3	0	109.3	T319 D323 D375 Y383	T319-K379 HydrophobicContact CG2-CD 4.15Å; T319-K379 HydrophobicContact CG2-CG 4.1Å; D323-K379 VanDerWaalsContact CG-NZ 3.28Å; D323-K379 VanDerWaalsContact OD1-CE 3.29Å; D323-K379 WeakPolarHBondContact OD1-CE 3.28Å; D323-K379 IonicContact OD1-NZ 3.43Å; D323-K379 PolarHBondContact OD1-NZ 3.45Å; D323-K379 IonicContact OD2-NZ 3.85Å; D323-K379 PolarHBondContact OD2-NZ 2.7Å; D375-K379 PolarHBondContact O-N 2.98Å; D375-K379 VanDerWaalsContact O-N 3.16Å; K379-Y383 WeakPolarHBondContact O-CB 3.43Å; K379-Y383 PolarHBondContact O-N 2.95Å
380	T	83.3	Confident	77.7	Confident	47 Å²	47	63.8 Å²	63.8	29%	0.288	30%	0.295	S	S	.	.	H	α-helix	trans	-62.5	-43.8	176.9	-54.8	0	0	0	0	112.2	F376 W378 K384	F376-T380 WeakPolarHBondContact O-CB 3.34Å; F376-T380 PolarHBondContact O-N 3.39Å; F376-T380 PolarHBondContact O-OG1 3.46Å; W378-T380 VanDerWaalsContact C-N 3.26Å; W378-T380 PolarHBondContact O-N 2.8Å; T380-K384 HydrophobicContact CG2-CD 4.09Å; T380-K384 WeakPolarHBondContact O-CB 3.46Å; T380-K384 VanDerWaalsContact O-CG 3.25Å; T380-K384 WeakPolarHBondContact O-CG 3.45Å; T380-K384 PolarHBondContact O-N 3.25Å
381	L	82.1	Confident	79.4	Confident	84 Å²	84	61.2 Å²	61.2	44%	0.44	28%	0.279	S	S	.	.	H	α-helix	trans	-67.7	-42.1	-178.3	-175.8	63.6	0	0	0	112.3	I151 N377 W378 R385	I151-L381 HydrophobicContact CG2-CD2 3.3Å; I151-L381 HydrophobicContact CG2-CG 4.43Å; N377-L381 WeakPolarHBondContact O-CB 3.3Å; N377-L381 PolarHBondContact O-N 3.2Å; W378-L381 PolarHBondContact O-N 2.86Å; W378-L381 VanDerWaalsContact O-N 3.13Å; L381-R385 VanDerWaalsContact O-CB 3.27Å; L381-R385 WeakPolarHBondContact O-CB 3.44Å; L381-R385 PolarHBondContact O-N 3.37Å
382	V	84.2	Confident	81.1	Confident	8 Å²	8	60 Å²	60	5%	0.048	27%	0.269	C	S	.	.	H	α-helix	trans	-68.8	-44.6	177.6	171.1	0	0	0	0	110.7	L148 W378 K384 R385 L386	L148-V382 HydrophobicContact CD2-CG2 3.84Å; W378-V382 HydrophobicContact CE3-CB 3.97Å; W378-V382 HydrophobicContact CE3-CG2 3.53Å; W378-V382 HydrophobicContact CZ3-CB 4.07Å; W378-V382 HydrophobicContact CZ3-CG1 4.27Å; W378-V382 HydrophobicContact CZ3-CG2 3.92Å; W378-V382 WeakPolarHBondContact O-CB 2.94Å; W378-V382 WeakPolarHBondContact O-CG2 3.36Å; W378-V382 PolarHBondContact O-N 3.17Å; V382-K384 PolarHBondContact O-N 3.35Å; V382-R385 PolarHBondContact O-N 2.94Å; V382-L386 HydrophobicContact CG1-CD1 3.49Å; V382-L386 VanDerWaalsContact CG1-CD1 3.49Å; V382-L386 HydrophobicContact CG1-CG 4.13Å; V382-L386 WeakPolarHBondContact O-CB 3.12Å; V382-L386 VanDerWaalsContact O-CG 3.3Å; V382-L386 WeakPolarHBondContact O-CG 3.36Å; V382-L386 PolarHBondContact O-N 3.39Å
383	Y	87.1	Confident	83	Confident	70 Å²	70	52.1 Å²	52.1	28%	0.275	24%	0.239	S	C	.	.	H	α-helix	trans	-57.7	-48.5	173.7	-111.7	-78.1	0	0	0	111.9	Q312 I315 K379 R385 G387	Q312-Y383 WeakPolarHBondContact CG-OH 3.36Å; I315-Y383 HydrophobicContact CB-CE2 4.12Å; I315-Y383 HydrophobicContact CD1-CD1 4.11Å; I315-Y383 HydrophobicContact CD1-CE1 3.89Å; I315-Y383 HydrophobicContact CD1-CE2 4.37Å; I315-Y383 HydrophobicContact CD1-CG 4.42Å; I315-Y383 HydrophobicContact CG2-CD2 3.68Å; I315-Y383 HydrophobicContact CG2-CE2 3.24Å; K379-Y383 WeakPolarHBondContact O-CB 3.43Å; K379-Y383 PolarHBondContact O-N 2.95Å; Y383-R385 VanDerWaalsContact C-N 3.35Å; Y383-R385 PolarHBondContact O-N 3.48Å; Y383-G387 PolarHBondContact O-N 2.85Å
384	K	86.9	Confident	84.9	Confident	140 Å²	140	46.9 Å²	46.9	61%	0.609	22%	0.215	S	C	*	.	H	α-helix	trans	-60.7	-44.4	177.1	-76.3	178.7	179	-177.8	0	111.4	T380 V382 G387 T388	T380-K384 HydrophobicContact CG2-CD 4.09Å; T380-K384 WeakPolarHBondContact O-CB 3.46Å; T380-K384 VanDerWaalsContact O-CG 3.25Å; T380-K384 WeakPolarHBondContact O-CG 3.45Å; T380-K384 PolarHBondContact O-N 3.25Å; V382-K384 PolarHBondContact O-N 3.35Å; K384-G387 PolarHBondContact O-N 3.46Å; K384-T388 VanDerWaalsContact O-CG2 3.26Å; K384-T388 WeakPolarHBondContact O-CG2 3.26Å; K384-T388 PolarHBondContact O-N 3.12Å; K384-T388 PolarHBondContact O-OG1 2.91Å
385	R	87.1	Confident	86.5	Confident	47 Å²	47	38.5 Å²	38.5	18%	0.177	18%	0.184	C	C	.	.	H	α-helix	trans	-64.2	-51.1	-179.8	-179.7	58.7	178.9	173.1	4.4	111.8	S146 L381 V382 Y383 G387 T388 L389 V415 Y445	S146-R385 VanDerWaalsContact CB-NH2 3.31Å; S146-R385 PolarHBondContact OG-NH2 3.34Å; L381-R385 VanDerWaalsContact O-CB 3.27Å; L381-R385 WeakPolarHBondContact O-CB 3.44Å; L381-R385 PolarHBondContact O-N 3.37Å; V382-R385 PolarHBondContact O-N 2.94Å; Y383-R385 VanDerWaalsContact C-N 3.35Å; Y383-R385 PolarHBondContact O-N 3.48Å; R385-G387 VanDerWaalsContact C-N 3.3Å; R385-G387 PolarHBondContact O-N 3.28Å; R385-T388 PolarHBondContact O-N 2.92Å; R385-T388 PolarHBondContact O-OG1 2.88Å; R385-L389 WeakPolarHBondContact O-CG 3.31Å; R385-L389 PolarHBondContact O-N 3.41Å; R385-L389 VanDerWaalsContact O-N 3.08Å; R385-V415 HydrophobicContact CG-CG2 4.44Å; R385-Y445 VanDerWaalsContact NH1-CE2 3.25Å; R385-Y445 PolarHBondContact NH1-OH 3.5Å
386	L	92	Very high	88	Confident	1 Å²	1	37 Å²	37	1%	0.005	18%	0.176	C	C	.	.	H	α-helix	trans	-62.1	-40.6	178.3	-68.5	169.7	0	0	0	111	L311 I315 V382 L389 M390 I411 L412 V415	L311-L386 HydrophobicContact CD1-CB 4.42Å; L311-L386 HydrophobicContact CD1-CD1 4.36Å; L311-L386 HydrophobicContact CD1-CD2 4.41Å; L311-L386 HydrophobicContact CD2-CB 4.15Å; I315-L386 HydrophobicContact CD1-CB 4.28Å; I315-L386 HydrophobicContact CD1-CD1 3.5Å; I315-L386 HydrophobicContact CG1-CD1 3.5Å; V382-L386 HydrophobicContact CG1-CD1 3.49Å; V382-L386 VanDerWaalsContact CG1-CD1 3.49Å; V382-L386 HydrophobicContact CG1-CG 4.13Å; V382-L386 WeakPolarHBondContact O-CB 3.12Å; V382-L386 VanDerWaalsContact O-CG 3.3Å; V382-L386 WeakPolarHBondContact O-CG 3.36Å; V382-L386 PolarHBondContact O-N 3.39Å; L386-L389 PolarHBondContact O-N 3Å; L386-M390 PolarHBondContact O-N 2.69Å; L386-I411 HydrophobicContact CB-CG2 4.49Å; L386-I411 HydrophobicContact CD2-CG2 3.63Å; L386-L412 HydrophobicContact CD1-CD2 3.96Å; L386-L412 HydrophobicContact CD2-CD2 4.06Å; L386-V415 HydrophobicContact CD2-CB 3.99Å; L386-V415 HydrophobicContact CD2-CG1 4.16Å; L386-V415 HydrophobicContact CD2-CG2 3.48Å; L386-V415 VanDerWaalsContact CD2-CG2 3.48Å; L386-V415 HydrophobicContact CG-CG2 4.37Å
387	G	92.1	Very high	89.3	Confident	1 Å²	1	30.1 Å²	30.1	1%	0.01	15%	0.146	C	C	.	.	H	α-helix	trans	-59.3	-50.1	174.5	0	0	0	0	0	112.3	Y383 K384 R385 L389 M390 E391	Y383-G387 PolarHBondContact O-N 2.85Å; K384-G387 PolarHBondContact O-N 3.46Å; R385-G387 VanDerWaalsContact C-N 3.3Å; R385-G387 PolarHBondContact O-N 3.28Å; G387-L389 VanDerWaalsContact C-N 3.29Å; G387-L389 PolarHBondContact O-N 2.95Å; G387-M390 WeakPolarHBondContact O-CB 3.36Å; G387-M390 PolarHBondContact O-N 3.44Å; G387-M390 VanDerWaalsContact O-N 3.1Å; G387-E391 WeakPolarHBondContact O-CG 3.27Å; G387-E391 PolarHBondContact O-N 3.45Å
388	T	90.9	Very high	90	Very high	44 Å²	44	27.6 Å²	27.6	27%	0.27	13%	0.131	S	C	.	.	H	α-helix	trans	-60.6	-37	177.4	58.4	0	0	0	0	113.2	K384 R385 I392	K384-T388 VanDerWaalsContact O-CG2 3.26Å; K384-T388 WeakPolarHBondContact O-CG2 3.26Å; K384-T388 PolarHBondContact O-N 3.12Å; K384-T388 PolarHBondContact O-OG1 2.91Å; R385-T388 PolarHBondContact O-N 2.92Å; R385-T388 PolarHBondContact O-OG1 2.88Å; T388-I392 WeakPolarHBondContact O-CB 3.44Å; T388-I392 WeakPolarHBondContact O-CD1 3.36Å; T388-I392 WeakPolarHBondContact O-CG1 3.07Å; T388-I392 PolarHBondContact O-N 3.11Å; T388-I392 VanDerWaalsContact O-N 3.08Å
389	L	93.2	Very high	90.8	Very high	1 Å²	1	27 Å²	27	1%	0.005	13%	0.129	C	C	.	.	H	α-helix	trans	-67	-41.5	175.2	-72.3	172.9	0	0	0	111.5	R385 L386 G387 I392 A393 I411 V415 V441 Y445	R385-L389 WeakPolarHBondContact O-CG 3.31Å; R385-L389 PolarHBondContact O-N 3.41Å; R385-L389 VanDerWaalsContact O-N 3.08Å; L386-L389 PolarHBondContact O-N 3Å; G387-L389 VanDerWaalsContact C-N 3.29Å; G387-L389 PolarHBondContact O-N 2.95Å; L389-I392 PolarHBondContact O-N 3.34Å; L389-A393 VanDerWaalsContact O-CB 3.22Å; L389-A393 WeakPolarHBondContact O-CB 3.29Å; L389-A393 PolarHBondContact O-N 3.38Å; L389-I411 HydrophobicContact CB-CG2 4.02Å; L389-I411 HydrophobicContact CD1-CG2 4.34Å; L389-V415 HydrophobicContact CD1-CG2 3.57Å; L389-V441 HydrophobicContact CB-CG1 4.34Å; L389-V441 HydrophobicContact CD2-CG1 4.22Å; L389-Y445 HydrophobicContact CD2-CD2 3.47Å; L389-Y445 VanDerWaalsContact CD2-CD2 3.47Å; L389-Y445 HydrophobicContact CD2-CE2 4.13Å; L389-Y445 HydrophobicContact CD2-CG 3.94Å
390	M	95.1	Very high	91.4	Very high	0 Å²	0	26 Å²	26	0%	0	12%	0.124	C	C	.	.	H	α-helix	trans	-60.8	-48.3	174.7	-176.2	62.8	79.7	0	0	111.4	T220 C224 A307 L311 L386 G387 I392 A393 L394 L407 I411	T220-M390 HydrophobicContact CG2-CB 4.46Å; C224-M390 VanDerWaalsContact SG-CG 3.52Å; A307-M390 HydrophobicContact CB-CE 3.7Å; A307-M390 HydrophobicContact CB-SD 3.97Å; L311-M390 HydrophobicContact CB-CE 4.07Å; L311-M390 HydrophobicContact CD2-CB 4.34Å; L311-M390 HydrophobicContact CD2-CE 3.79Å; L311-M390 HydrophobicContact CG-CE 4.49Å; L386-M390 PolarHBondContact O-N 2.69Å; G387-M390 WeakPolarHBondContact O-CB 3.36Å; G387-M390 PolarHBondContact O-N 3.44Å; G387-M390 VanDerWaalsContact O-N 3.1Å; M390-I392 VanDerWaalsContact C-N 3.34Å; M390-I392 PolarHBondContact O-N 3.1Å; M390-A393 PolarHBondContact O-N 3.42Å; M390-L394 HydrophobicContact CG-CD1 4.1Å; M390-L394 WeakPolarHBondContact O-CG 3.4Å; M390-L394 PolarHBondContact O-N 3.02Å; M390-L394 HydrophobicContact SD-CD1 4.18Å; M390-L394 HydrophobicContact SD-CG 4.21Å; M390-L407 HydrophobicContact SD-CD2 4.21Å; M390-L407 HydrophobicContact SD-CG 4.4Å; M390-I411 HydrophobicContact CB-CD1 3.97Å; M390-I411 HydrophobicContact CE-CD1 3.33Å; M390-I411 HydrophobicContact CG-CD1 4.36Å; M390-I411 HydrophobicContact SD-CD1 3.51Å; M390-I411 VanDerWaalsContact SD-CD1 3.51Å
391	E	94.4	Very high	91.8	Very high	6 Å²	6	29.7 Å²	29.7	3%	0.028	13%	0.132	C	C	.	.	H	α-helix	trans	-59.1	-44.3	178.6	-68.3	170.8	-167	0	0	112.2	R209 H212 N213 T220 F223 G387 C395	R209-E391 HydrophobicContact CG-CB 4.45Å; R209-E391 IonicContact NE-OE2 3.59Å; H212-E391 IonicContact CE1-OE1 3.91Å; H212-E391 IonicContact ND1-OE1 3.84Å; N213-E391 PolarHBondContact ND2-OE2 3.04Å; N213-E391 PolarHBondContact OD1-OE2 3.08Å; T220-E391 WeakPolarHBondContact CB-OE1 3.5Å; T220-E391 HydrophobicContact CG2-CG 3.68Å; T220-E391 PolarHBondContact OG1-OE1 3.14Å; F223-E391 HydrophobicContact CB-CG 4.49Å; F223-E391 HydrophobicContact CD1-CB 3.96Å; F223-E391 HydrophobicContact CD1-CG 3.67Å; F223-E391 HydrophobicContact CE1-CB 3.96Å; F223-E391 HydrophobicContact CE1-CG 4.2Å; F223-E391 WeakPolarHBondContact CE1-O 3.29Å; F223-E391 HydrophobicContact CG-CG 4.22Å; G387-E391 WeakPolarHBondContact O-CG 3.27Å; G387-E391 PolarHBondContact O-N 3.45Å; E391-C395 PolarHBondContact O-N 3.14Å; E391-C395 PolarHBondContact O-SG 3.27Å
392	I	93.5	Very high	92.4	Very high	2 Å²	2	26.3 Å²	26.3	1%	0.01	11%	0.114	C	C	.	.	H	α-helix	trans	-67.2	-42.8	178.7	-68	165	0	0	0	110.8	R209 T388 L389 M390 L394 C395 L444 Y445 Y448 Y449	R209-I392 VanDerWaalsContact CZ-CG1 3.45Å; R209-I392 VanDerWaalsContact NH2-CG1 3.34Å; T388-I392 WeakPolarHBondContact O-CB 3.44Å; T388-I392 WeakPolarHBondContact O-CD1 3.36Å; T388-I392 WeakPolarHBondContact O-CG1 3.07Å; T388-I392 PolarHBondContact O-N 3.11Å; T388-I392 VanDerWaalsContact O-N 3.08Å; L389-I392 PolarHBondContact O-N 3.34Å; M390-I392 VanDerWaalsContact C-N 3.34Å; M390-I392 PolarHBondContact O-N 3.1Å; I392-L394 PolarHBondContact O-N 2.9Å; I392-C395 WeakPolarHBondContact O-CB 3.14Å; I392-C395 PolarHBondContact O-N 2.88Å; I392-L444 HydrophobicContact CG2-CB 4.33Å; I392-Y445 HydrophobicContact CD1-CD2 3.59Å; I392-Y445 HydrophobicContact CD1-CE2 3.92Å; I392-Y448 HydrophobicContact CG2-CD2 3.73Å; I392-Y448 HydrophobicContact CG2-CG 4.25Å; I392-Y449 HydrophobicContact CD1-CD2 4.17Å
393	A	95.9	Very high	92.9	Very high	1 Å²	1	28.8 Å²	28.8	1%	0.008	12%	0.123	C	C	.	.	H	α-helix	trans	-59.4	-47.3	179.4	0	0	0	0	0	111.1	L389 M390 C395 S396 V399 L407 V441	L389-A393 VanDerWaalsContact O-CB 3.22Å; L389-A393 WeakPolarHBondContact O-CB 3.29Å; L389-A393 PolarHBondContact O-N 3.38Å; M390-A393 PolarHBondContact O-N 3.42Å; A393-C395 PolarHBondContact O-N 3.02Å; A393-S396 PolarHBondContact O-N 3.03Å; A393-S396 VanDerWaalsContact O-N 3.1Å; A393-V399 HydrophobicContact CB-CG1 4.12Å; A393-V399 WeakPolarHBondContact O-CG1 3.48Å; A393-L407 HydrophobicContact CB-CD1 4.34Å; A393-V441 HydrophobicContact CB-CG2 4.1Å
394	L	96.1	Very high	93.4	Very high	9 Å²	9	26.3 Å²	26.3	5%	0.047	12%	0.115	C	C	.	.	H	α-helix	trans	-65.6	-18.1	-179.1	-71.1	177	0	0	0	114.4	R201 F223 C224 V227 M390 I392 S396 V399 Y400 L407	R201-L394 PolarHBondContact NH1-O 3.24Å; R201-L394 PolarHBondContact NH2-O 2.58Å; F223-L394 HydrophobicContact CE1-CB 4.17Å; C224-L394 HydrophobicContact CB-CD1 3.99Å; C224-L394 VanDerWaalsContact SG-CD1 3.59Å; V227-L394 HydrophobicContact CG1-CB 4.29Å; M390-L394 HydrophobicContact CG-CD1 4.1Å; M390-L394 WeakPolarHBondContact O-CG 3.4Å; M390-L394 PolarHBondContact O-N 3.02Å; M390-L394 HydrophobicContact SD-CD1 4.18Å; M390-L394 HydrophobicContact SD-CG 4.21Å; I392-L394 PolarHBondContact O-N 2.9Å; L394-S396 PolarHBondContact O-N 2.7Å; L394-V399 HydrophobicContact CD2-CG2 4.28Å; L394-Y400 HydrophobicContact CD2-CE2 4.48Å; L394-L407 HydrophobicContact CD2-CD2 4.1Å
395	C	94.9	Very high	93.9	Very high	0 Å²	0	19.7 Å²	19.7	0%	0	9%	0.086	C	C	.	.	T	Hydrogen-bonded Turn	trans	-64.7	-22.4	172.7	-66.4	0	0	0	0	113.2	D202 R209 E391 I392 A393 Y448	D202-C395 WeakPolarHBondContact CA-O 3.21Å; D202-C395 WeakPolarHBondContact CB-O 3.24Å; D202-C395 VanDerWaalsContact CG-O 3.25Å; R209-C395 WeakPolarHBondContact CD-SG 3.15Å; E391-C395 PolarHBondContact O-N 3.14Å; E391-C395 PolarHBondContact O-SG 3.27Å; I392-C395 WeakPolarHBondContact O-CB 3.14Å; I392-C395 PolarHBondContact O-N 2.88Å; A393-C395 PolarHBondContact O-N 3.02Å; C395-Y448 HydrophobicContact CB-CE2 4.12Å
396	S	94.8	Very high	94.4	Very high	2 Å²	2	17.5 Å²	17.5	1%	0.014	8%	0.078	C	C	.	.	S	Bend	trans	-104.9	129.8	175.8	-174.7	0	0	0	0	111.1	D202 A393 L394 E398 V399	D202-S396 WeakPolarHBondContact OD2-CA 3.37Å; A393-S396 PolarHBondContact O-N 3.03Å; A393-S396 VanDerWaalsContact O-N 3.1Å; L394-S396 PolarHBondContact O-N 2.7Å; S396-E398 PolarHBondContact O-N 2.8Å; S396-E398 VanDerWaalsContact O-N 3.11Å; S396-E398 WeakPolarHBondContact OG-CB 3.46Å; S396-E398 PolarHBondContact OG-N 2.98Å; S396-V399 WeakPolarHBondContact O-CG2 3.25Å; S396-V399 PolarHBondContact O-N 3.42Å
397	L	94.6	Very high	94.6	Very high	3 Å²	3	17.8 Å²	17.8	2%	0.016	8%	0.08	C	C	.	.	G	3₁₀ helix	trans	-61.6	-21.7	176.1	-171.3	63.2	0	0	0	112.2	N182 L185 Y186 A198 D202 V399 Y400	N182-L397 HydrophobicContact CB-CD1 3.59Å; N182-L397 HydrophobicContact CB-CD2 4.34Å; N182-L397 HydrophobicContact CB-CG 4.39Å; N182-L397 WeakPolarHBondContact ND2-CD1 3.42Å; L185-L397 HydrophobicContact CB-CD2 3.83Å; L185-L397 HydrophobicContact CD1-CD1 4.39Å; L185-L397 HydrophobicContact CD1-CD2 3.77Å; L185-L397 HydrophobicContact CG-CD2 4.36Å; Y186-L397 HydrophobicContact CD2-CD2 4.32Å; Y186-L397 HydrophobicContact CE2-CD2 3.72Å; Y186-L397 HydrophobicContact CE2-CG 4.1Å; A198-L397 HydrophobicContact CB-CD2 3.74Å; D202-L397 VanDerWaalsContact CG-N 3.34Å; D202-L397 WeakPolarHBondContact OD1-CB 3.46Å; D202-L397 PolarHBondContact OD1-N 3.02Å; D202-L397 PolarHBondContact OD2-N 3.45Å; D202-L397 VanDerWaalsContact OD2-N 3.17Å; L397-V399 PolarHBondContact O-N 3.27Å; L397-V399 VanDerWaalsContact O-N 3.14Å; L397-Y400 HydrophobicContact CD1-CD2 4Å; L397-Y400 PolarHBondContact O-N 3.5Å; L397-Y400 VanDerWaalsContact O-N 3.14Å
398	E	93.4	Very high	94.9	Very high	38 Å²	38	17.8 Å²	17.8	18%	0.178	8%	0.079	C	C	.	.	G	3₁₀ helix	trans	-56.6	-28.9	-179.5	-76.5	-163.6	-166.8	0	0	113.9	Y186 S396 Y400 R401 L440	Y186-E398 WeakPolarHBondContact OH-CA 3.48Å; Y186-E398 PolarHBondContact OH-N 3.33Å; S396-E398 PolarHBondContact O-N 2.8Å; S396-E398 VanDerWaalsContact O-N 3.11Å; S396-E398 WeakPolarHBondContact OG-CB 3.46Å; S396-E398 PolarHBondContact OG-N 2.98Å; E398-Y400 PolarHBondContact O-N 3.14Å; E398-R401 VanDerWaalsContact CB-NH2 3.29Å; E398-R401 VanDerWaalsContact CG-NH2 3.34Å; E398-R401 VanDerWaalsContact O-CG 3.24Å; E398-R401 WeakPolarHBondContact O-CG 3.28Å; E398-R401 PolarHBondContact O-N 3.14Å; E398-R401 PolarHBondContact O-NE 3.03Å; E398-R401 IonicContact OE2-CZ 2.68Å; E398-R401 IonicContact OE2-NH2 2.6Å; E398-R401 PolarHBondContact OE2-NH2 3.17Å; E398-L440 HydrophobicContact CB-CD2 4.12Å
399	V	94.3	Very high	95.2	Very high	1 Å²	1	15.7 Å²	15.7	1%	0.006	7%	0.066	C	C	.	.	G	3₁₀ helix	trans	-69.1	-22.7	-178.5	-55.9	0	0	0	0	113.1	A393 L394 S396 L397 R401 F402 L407 L440 L444	A393-V399 HydrophobicContact CB-CG1 4.12Å; A393-V399 WeakPolarHBondContact O-CG1 3.48Å; L394-V399 HydrophobicContact CD2-CG2 4.28Å; S396-V399 WeakPolarHBondContact O-CG2 3.25Å; S396-V399 PolarHBondContact O-N 3.42Å; L397-V399 PolarHBondContact O-N 3.27Å; L397-V399 VanDerWaalsContact O-N 3.14Å; V399-R401 PolarHBondContact O-N 3.38Å; V399-F402 PolarHBondContact O-N 3.33Å; V399-L407 HydrophobicContact CB-CD1 4.13Å; V399-L407 HydrophobicContact CB-CD2 4.2Å; V399-L407 HydrophobicContact CG1-CD1 4.4Å; V399-L407 HydrophobicContact CG2-CD2 4.07Å; V399-L440 HydrophobicContact CG1-CD2 4.09Å; V399-L444 HydrophobicContact CG1-CD1 3.71Å
400	Y	92.9	Very high	95.3	Very high	42 Å²	42	15.6 Å²	15.6	17%	0.165	7%	0.066	C	C	.	.	G	3₁₀ helix	trans	-71.7	-5.1	178.2	-77	-85.4	0	0	0	114	P180 R201 D231 L394 L397 E398 F402	P180-Y400 HydrophobicContact CG-CD1 3.78Å; P180-Y400 HydrophobicContact CG-CE1 3.38Å; R201-Y400 VanDerWaalsContact NH2-CE2 3.34Å; D231-Y400 VanDerWaalsContact OD2-CE2 3.25Å; D231-Y400 WeakPolarHBondContact OD2-CE2 3.38Å; D231-Y400 PolarHBondContact OD2-OH 3.35Å; L394-Y400 HydrophobicContact CD2-CE2 4.48Å; L397-Y400 HydrophobicContact CD1-CD2 4Å; L397-Y400 PolarHBondContact O-N 3.5Å; L397-Y400 VanDerWaalsContact O-N 3.14Å; E398-Y400 PolarHBondContact O-N 3.14Å; Y400-F402 PolarHBondContact O-N 3.01Å
401	R	92.2	Very high	95.3	Very high	124 Å²	124	15.6 Å²	15.6	47%	0.468	7%	0.066	S	C	.	.	G	3₁₀ helix	trans	-65.3	-22.3	165.6	80.5	-179.2	72.6	151.6	-5.4	112.1	E398 V399	E398-R401 VanDerWaalsContact CB-NH2 3.29Å; E398-R401 VanDerWaalsContact CG-NH2 3.34Å; E398-R401 VanDerWaalsContact O-CG 3.24Å; E398-R401 WeakPolarHBondContact O-CG 3.28Å; E398-R401 PolarHBondContact O-N 3.14Å; E398-R401 PolarHBondContact O-NE 3.03Å; E398-R401 IonicContact OE2-CZ 2.68Å; E398-R401 IonicContact OE2-NH2 2.6Å; E398-R401 PolarHBondContact OE2-NH2 3.17Å; V399-R401 PolarHBondContact O-N 3.38Å
402	F	95.1	Very high	95.3	Very high	12 Å²	12	15.3 Å²	15.3	5%	0.053	7%	0.065	C	C	.	.	S	Bend	trans	-99.5	150	178.7	-57.6	-72.4	0	0	0	110.4	Q179 V399 Y400 C406 D433 E436 C437 L440	Q179-F402 PolarHBondContact NE2-O 3.38Å; V399-F402 PolarHBondContact O-N 3.33Å; Y400-F402 PolarHBondContact O-N 3.01Å; F402-C406 HydrophobicContact CB-CB 4.21Å; F402-D433 HydrophobicContact CD1-CB 4.43Å; F402-D433 HydrophobicContact CE1-CB 4.46Å; F402-E436 HydrophobicContact CE1-CB 4.26Å; F402-E436 HydrophobicContact CZ-CB 4.12Å; F402-E436 HydrophobicContact CZ-CG 4.03Å; F402-C437 HydrophobicContact CD1-CB 4.04Å; F402-C437 HydrophobicContact CD2-CB 3.93Å; F402-C437 HydrophobicContact CE1-CB 4Å; F402-C437 HydrophobicContact CE2-CB 3.89Å; F402-C437 HydrophobicContact CG-CB 4.01Å; F402-C437 HydrophobicContact CZ-CB 3.92Å; F402-L440 HydrophobicContact CD2-CD2 4.48Å; F402-L440 HydrophobicContact CE2-CD2 3.79Å
403	R	95.2	Very high	95.3	Very high	61 Å²	61	15.4 Å²	15.4	23%	0.23	7%	0.066	C	C	.	.			trans	-59.1	144.4	167.4	-82.1	176.8	65.2	-161.3	0.4	110.8	E175 V405 C406 L407 C427 G428	E175-R403 WeakPolarHBondContact OE1-CB 3.36Å; E175-R403 IonicContact OE1-NE 3.27Å; E175-R403 IonicContact OE2-CZ 3.65Å; E175-R403 VanDerWaalsContact OE2-CZ 3.29Å; E175-R403 IonicContact OE2-NE 3.96Å; E175-R403 PolarHBondContact OE2-NE 3.1Å; E175-R403 IonicContact OE2-NH2 3.98Å; E175-R403 PolarHBondContact OE2-NH2 3.45Å; R403-V405 PolarHBondContact O-N 2.69Å; R403-C406 HydrophobicContact CB-CB 4.06Å; R403-C406 WeakPolarHBondContact O-CA 3.41Å; R403-C406 WeakPolarHBondContact O-CB 3.36Å; R403-C406 PolarHBondContact O-N 3.02Å; R403-L407 PolarHBondContact O-N 3.05Å; R403-C427 PolarHBondContact NH1-O 3.37Å; R403-C427 VanDerWaalsContact NH1-O 3.14Å; R403-C427 PolarHBondContact NH2-O 3.29Å; R403-G428 PolarHBondContact NH1-O 3.27Å; R403-G428 VanDerWaalsContact NH1-O 3.14Å
404	P	96.4	Very high	95.1	Very high	18 Å²	18	15.9 Å²	15.9	12%	0.117	7%	0.068	C	C	.	.	H	α-helix	trans	-46.9	-41.8	172.2	-31.4	34.2	0	0	0	114.6	E175 Q179 A307 F310 L407 A408	E175-P404 HydrophobicContact CG-CB 4.11Å; E175-P404 HydrophobicContact CG-CG 3.81Å; E175-P404 WeakPolarHBondContact OE1-CD 3.48Å; Q179-P404 HydrophobicContact CG-CG 4.44Å; A307-P404 HydrophobicContact CB-CB 4.19Å; A307-P404 WeakPolarHBondContact CB-O 3.46Å; F310-P404 HydrophobicContact CD2-CB 4.11Å; F310-P404 HydrophobicContact CE2-CB 3.96Å; P404-L407 PolarHBondContact O-N 3.17Å; P404-A408 PolarHBondContact O-N 2.78Å; P404-A408 VanDerWaalsContact O-N 3.08Å
405	V	97.2	Very high	94.7	Very high	0 Å²	0	15.5 Å²	15.5	0%	0	7%	0.066	C	C	.	.	H	α-helix	trans	-64.1	-43.6	175.8	-177.9	0	0	0	0	111.5	L172 E175 F310 F314 R403 L407 A408 L409 C427 V429	L172-V405 HydrophobicContact CD2-CG2 3.47Å; L172-V405 VanDerWaalsContact CD2-CG2 3.47Å; E175-V405 WeakPolarHBondContact OE1-CG2 3.24Å; E175-V405 PolarHBondContact OE1-N 3.24Å; F310-V405 HydrophobicContact CD1-CB 4.32Å; F310-V405 HydrophobicContact CD1-CG1 4.43Å; F310-V405 HydrophobicContact CD1-CG2 3.48Å; F310-V405 VanDerWaalsContact CD1-CG2 3.48Å; F310-V405 HydrophobicContact CD2-CG2 3.96Å; F310-V405 HydrophobicContact CE1-CB 4.44Å; F310-V405 HydrophobicContact CE1-CG2 3.2Å; F310-V405 HydrophobicContact CE2-CG2 3.72Å; F310-V405 HydrophobicContact CG-CB 4.42Å; F310-V405 HydrophobicContact CG-CG2 3.84Å; F310-V405 HydrophobicContact CZ-CG2 3.32Å; F314-V405 HydrophobicContact CE2-CG1 4.38Å; F314-V405 HydrophobicContact CZ-CG1 4.17Å; R403-V405 PolarHBondContact O-N 2.69Å; V405-L407 VanDerWaalsContact C-N 3.31Å; V405-L407 PolarHBondContact O-N 2.96Å; V405-A408 PolarHBondContact O-N 3.2Å; V405-L409 HydrophobicContact CG1-CD1 4.1Å; V405-L409 HydrophobicContact CG1-CG 4.42Å; V405-L409 WeakPolarHBondContact O-CG 3.33Å; V405-L409 PolarHBondContact O-N 3.39Å; V405-C427 HydrophobicContact CG1-CB 3.71Å; V405-V429 HydrophobicContact CG1-CG2 4.38Å
406	C	97.3	Very high	94.3	Very high	2 Å²	2	16.3 Å²	16.3	1%	0.014	7%	0.074	C	C	.	.	H	α-helix	trans	-62.8	-39.9	178.7	-177.4	0	0	0	0	111.1	F402 R403 L409 G410 V429	F402-C406 HydrophobicContact CB-CB 4.21Å; R403-C406 HydrophobicContact CB-CB 4.06Å; R403-C406 WeakPolarHBondContact O-CA 3.41Å; R403-C406 WeakPolarHBondContact O-CB 3.36Å; R403-C406 PolarHBondContact O-N 3.02Å; C406-L409 PolarHBondContact O-N 2.81Å; C406-G410 PolarHBondContact O-N 3.27Å; C406-V429 HydrophobicContact CB-CG1 3.66Å; C406-V429 HydrophobicContact CB-CG2 4.45Å
407	L	97.4	Very high	94	Very high	7 Å²	7	16.5 Å²	16.5	4%	0.037	8%	0.075	C	C	.	.	H	α-helix	trans	-61.9	-44.6	174.4	-178	58.5	0	0	0	112	A307 M390 A393 L394 V399 R403 P404 V405 G410 I411 V441	A307-L407 HydrophobicContact CB-CB 4.2Å; A307-L407 HydrophobicContact CB-CD2 3.86Å; A307-L407 HydrophobicContact CB-CG 4.2Å; M390-L407 HydrophobicContact SD-CD2 4.21Å; M390-L407 HydrophobicContact SD-CG 4.4Å; A393-L407 HydrophobicContact CB-CD1 4.34Å; L394-L407 HydrophobicContact CD2-CD2 4.1Å; V399-L407 HydrophobicContact CB-CD1 4.13Å; V399-L407 HydrophobicContact CB-CD2 4.2Å; V399-L407 HydrophobicContact CG1-CD1 4.4Å; V399-L407 HydrophobicContact CG2-CD2 4.07Å; R403-L407 PolarHBondContact O-N 3.05Å; P404-L407 PolarHBondContact O-N 3.17Å; V405-L407 VanDerWaalsContact C-N 3.31Å; V405-L407 PolarHBondContact O-N 2.96Å; L407-G410 PolarHBondContact O-N 3.13Å; L407-I411 HydrophobicContact CD1-CD1 4.25Å; L407-I411 HydrophobicContact CG-CD1 4.23Å; L407-I411 WeakPolarHBondContact O-CG1 3.45Å; L407-I411 PolarHBondContact O-N 3.46Å; L407-V441 HydrophobicContact CD1-CG2 4.12Å
408	A	97.4	Very high	93.8	Very high	0 Å²	0	20.7 Å²	20.7	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-60.9	-46.9	175.6	0	0	0	0	0	112.1	F310 L311 F314 P404 V405 G410 I411 L412	F310-A408 HydrophobicContact CB-CB 3.73Å; L311-A408 HydrophobicContact CB-CB 4.12Å; F314-A408 HydrophobicContact CD2-CB 4.19Å; F314-A408 HydrophobicContact CE2-CB 4.09Å; P404-A408 PolarHBondContact O-N 2.78Å; P404-A408 VanDerWaalsContact O-N 3.08Å; V405-A408 PolarHBondContact O-N 3.2Å; A408-G410 PolarHBondContact O-N 2.95Å; A408-I411 PolarHBondContact O-N 2.87Å; A408-L412 WeakPolarHBondContact O-CG 3.2Å; A408-L412 PolarHBondContact O-N 3.38Å; A408-L412 VanDerWaalsContact O-N 3.15Å
409	L	97.3	Very high	93.6	Very high	0 Å²	0	20.5 Å²	20.5	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-62.6	-40.6	175.8	-69.4	173.8	0	0	0	112.2	F314 V405 C406 I411 L412 A413 L420 L423 A424 V434	F314-L409 HydrophobicContact CD2-CD2 4.11Å; F314-L409 HydrophobicContact CE2-CD2 3.7Å; F314-L409 HydrophobicContact CE2-CG 3.93Å; F314-L409 HydrophobicContact CZ-CD2 4.11Å; F314-L409 HydrophobicContact CZ-CG 4.46Å; V405-L409 HydrophobicContact CG1-CD1 4.1Å; V405-L409 HydrophobicContact CG1-CG 4.42Å; V405-L409 WeakPolarHBondContact O-CG 3.33Å; V405-L409 PolarHBondContact O-N 3.39Å; C406-L409 PolarHBondContact O-N 2.81Å; L409-I411 VanDerWaalsContact C-N 3.32Å; L409-I411 PolarHBondContact O-N 2.71Å; L409-L412 PolarHBondContact O-N 3.03Å; L409-A413 WeakPolarHBondContact O-CB 2.98Å; L409-A413 PolarHBondContact O-N 3.23Å; L409-L420 HydrophobicContact CD2-CD2 4.31Å; L409-L423 HydrophobicContact CD2-CB 4.49Å; L409-L423 HydrophobicContact CD2-CD2 3.52Å; L409-L423 HydrophobicContact CD2-CG 3.85Å; L409-A424 HydrophobicContact CD1-CB 4.01Å; L409-V434 HydrophobicContact CB-CG1 3.87Å; L409-V434 HydrophobicContact CB-CG2 4.05Å; L409-V434 HydrophobicContact CD1-CG2 4.13Å
410	G	96.4	Very high	93.6	Very high	0 Å²	0	20.6 Å²	20.6	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-61.1	-40.1	177.3	0	0	0	0	0	112.2	C406 L407 A408 A413 Q414 A438	C406-G410 PolarHBondContact O-N 3.27Å; L407-G410 PolarHBondContact O-N 3.13Å; A408-G410 PolarHBondContact O-N 2.95Å; G410-A413 PolarHBondContact O-N 3.41Å; G410-Q414 WeakPolarHBondContact O-CB 3.45Å; G410-Q414 PolarHBondContact O-N 2.77Å; G410-A438 WeakPolarHBondContact O-CA 3.47Å; G410-A438 VanDerWaalsContact O-CB 3.3Å; G410-A438 WeakPolarHBondContact O-CB 3.28Å
411	I	95.4	Very high	93.7	Very high	0 Å²	0	22.6 Å²	22.6	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-66.4	-43.5	175.8	-69.5	163.9	0	0	0	111.3	L311 L386 L389 M390 L407 A408 L409 A413 Q414 V415 V441	L311-I411 HydrophobicContact CD1-CG2 4.44Å; L386-I411 HydrophobicContact CB-CG2 4.49Å; L386-I411 HydrophobicContact CD2-CG2 3.63Å; L389-I411 HydrophobicContact CB-CG2 4.02Å; L389-I411 HydrophobicContact CD1-CG2 4.34Å; M390-I411 HydrophobicContact CB-CD1 3.97Å; M390-I411 HydrophobicContact CE-CD1 3.33Å; M390-I411 HydrophobicContact CG-CD1 4.36Å; M390-I411 HydrophobicContact SD-CD1 3.51Å; M390-I411 VanDerWaalsContact SD-CD1 3.51Å; L407-I411 HydrophobicContact CD1-CD1 4.25Å; L407-I411 HydrophobicContact CG-CD1 4.23Å; L407-I411 WeakPolarHBondContact O-CG1 3.45Å; L407-I411 PolarHBondContact O-N 3.46Å; A408-I411 PolarHBondContact O-N 2.87Å; L409-I411 VanDerWaalsContact C-N 3.32Å; L409-I411 PolarHBondContact O-N 2.71Å; I411-A413 VanDerWaalsContact C-N 3.34Å; I411-A413 PolarHBondContact O-N 2.87Å; I411-Q414 PolarHBondContact O-N 2.96Å; I411-V415 PolarHBondContact O-N 3.22Å; I411-V415 VanDerWaalsContact O-N 3.15Å; I411-V441 HydrophobicContact CG1-CG1 4.18Å; I411-V441 HydrophobicContact CG1-CG2 4.04Å
412	L	94.4	Very high	93.8	Very high	0 Å²	0	19.9 Å²	19.9	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-62.6	-41.5	175.1	-63.8	168.3	0	0	0	111.6	L311 F314 L386 A408 L409 Q414 V415 G416 I417 L420	L311-L412 HydrophobicContact CD1-CD2 3.77Å; L311-L412 HydrophobicContact CD1-CG 3.96Å; F314-L412 HydrophobicContact CB-CD1 3.48Å; F314-L412 VanDerWaalsContact CB-CD1 3.48Å; F314-L412 HydrophobicContact CD2-CD1 3.62Å; F314-L412 HydrophobicContact CG-CD1 3.89Å; L386-L412 HydrophobicContact CD1-CD2 3.96Å; L386-L412 HydrophobicContact CD2-CD2 4.06Å; A408-L412 WeakPolarHBondContact O-CG 3.2Å; A408-L412 PolarHBondContact O-N 3.38Å; A408-L412 VanDerWaalsContact O-N 3.15Å; L409-L412 PolarHBondContact O-N 3.03Å; L412-Q414 VanDerWaalsContact C-N 3.33Å; L412-Q414 PolarHBondContact O-N 3.01Å; L412-V415 PolarHBondContact O-N 2.85Å; L412-G416 PolarHBondContact O-N 3.11Å; L412-G416 VanDerWaalsContact O-N 3.1Å; L412-I417 HydrophobicContact CB-CB 4.4Å; L412-I417 HydrophobicContact CB-CD1 4.16Å; L412-I417 HydrophobicContact CD2-CD1 3.4Å; L412-I417 HydrophobicContact CG-CD1 4.36Å; L412-I417 PolarHBondContact O-N 2.94Å; L412-I417 VanDerWaalsContact O-N 3.09Å; L412-L420 HydrophobicContact CB-CD1 3.75Å; L412-L420 HydrophobicContact CB-CD2 4.07Å; L412-L420 HydrophobicContact CD1-CD2 4.04Å
413	A	93.3	Very high	93.8	Very high	3 Å²	3	19.4 Å²	19.4	3%	0.025	11%	0.112	C	C	.	.	H	α-helix	trans	-65.9	-35.1	177.4	0	0	0	0	0	112.1	R145 L409 G410 I411 V415 G416 L420 V434 A438	R145-A413 PolarHBondContact NH2-O 3.01Å; L409-A413 WeakPolarHBondContact O-CB 2.98Å; L409-A413 PolarHBondContact O-N 3.23Å; G410-A413 PolarHBondContact O-N 3.41Å; I411-A413 VanDerWaalsContact C-N 3.34Å; I411-A413 PolarHBondContact O-N 2.87Å; A413-V415 VanDerWaalsContact C-N 3.33Å; A413-G416 PolarHBondContact O-N 3.03Å; A413-G416 VanDerWaalsContact O-N 3.16Å; A413-L420 HydrophobicContact CB-CD1 3.8Å; A413-V434 HydrophobicContact CB-CG1 4.19Å; A413-A438 HydrophobicContact CB-CB 4.12Å
414	Q	90.3	Very high	93.9	Very high	11 Å²	11	16.5 Å²	16.5	5%	0.051	10%	0.101	C	C	.	.	H	α-helix	trans	-68.2	-33.3	176.6	-177.8	59.7	6.2	0	0	112.7	G410 I411 L412 G416 A438 V441 G442	G410-Q414 WeakPolarHBondContact O-CB 3.45Å; G410-Q414 PolarHBondContact O-N 2.77Å; I411-Q414 PolarHBondContact O-N 2.96Å; L412-Q414 VanDerWaalsContact C-N 3.33Å; L412-Q414 PolarHBondContact O-N 3.01Å; Q414-G416 VanDerWaalsContact C-N 3.27Å; Q414-A438 HydrophobicContact CB-CB 4.25Å; Q414-A438 PolarHBondContact OE1-O 3.45Å; Q414-V441 HydrophobicContact CG-CG1 4.35Å; Q414-G442 VanDerWaalsContact NE2-CA 3.31Å
415	V	87.6	Confident	93.9	Very high	1 Å²	1	20.8 Å²	20.8	1%	0.006	12%	0.123	C	C	.	.	H	α-helix	trans	-74.2	-20.1	172.4	158.8	0	0	0	0	112	L148 R385 L386 L389 I411 L412 A413 I417	L148-V415 HydrophobicContact CD1-CB 4.04Å; L148-V415 HydrophobicContact CD1-CG1 3.34Å; L148-V415 HydrophobicContact CD1-CG2 4.19Å; L148-V415 HydrophobicContact CD2-CG1 3.46Å; L148-V415 VanDerWaalsContact CD2-CG1 3.46Å; L148-V415 HydrophobicContact CG-CG1 3.91Å; L148-V415 PolarHBondContact N-O 2.89Å; R385-V415 HydrophobicContact CG-CG2 4.44Å; L386-V415 HydrophobicContact CD2-CB 3.99Å; L386-V415 HydrophobicContact CD2-CG1 4.16Å; L386-V415 HydrophobicContact CD2-CG2 3.48Å; L386-V415 VanDerWaalsContact CD2-CG2 3.48Å; L386-V415 HydrophobicContact CG-CG2 4.37Å; L389-V415 HydrophobicContact CD1-CG2 3.57Å; I411-V415 PolarHBondContact O-N 3.22Å; I411-V415 VanDerWaalsContact O-N 3.15Å; L412-V415 PolarHBondContact O-N 2.85Å; A413-V415 VanDerWaalsContact C-N 3.33Å; V415-I417 HydrophobicContact CG1-CD1 4.02Å; V415-I417 HydrophobicContact CG1-CG1 4.02Å
416	G	87.1	Confident	93.8	Very high	17 Å²	17	23.8 Å²	23.8	18%	0.175	14%	0.139	C	C	.	.	T	Hydrogen-bonded Turn	trans	90.4	25.6	176.9	0	0	0	0	0	114.3	L412 A413 Q414	L412-G416 PolarHBondContact O-N 3.11Å; L412-G416 VanDerWaalsContact O-N 3.1Å; A413-G416 PolarHBondContact O-N 3.03Å; A413-G416 VanDerWaalsContact O-N 3.16Å; Q414-G416 VanDerWaalsContact C-N 3.27Å
417	I	89.7	Confident	93.7	Very high	7 Å²	7	24 Å²	24	4%	0.036	14%	0.141	C	C	.	.			trans	-69.2	134.1	170.9	-66.4	165.4	0	0	0	109	I156 C158 V318 L412 V415 L420	I156-I417 HydrophobicContact CB-CG1 4.48Å; I156-I417 HydrophobicContact CG2-CG1 4.13Å; C158-I417 HydrophobicContact CB-CG2 4.11Å; V318-I417 HydrophobicContact CG2-CD1 4.45Å; V318-I417 HydrophobicContact CG2-CG2 3.99Å; L412-I417 HydrophobicContact CB-CB 4.4Å; L412-I417 HydrophobicContact CB-CD1 4.16Å; L412-I417 HydrophobicContact CD2-CD1 3.4Å; L412-I417 HydrophobicContact CG-CD1 4.36Å; L412-I417 PolarHBondContact O-N 2.94Å; L412-I417 VanDerWaalsContact O-N 3.09Å; V415-I417 HydrophobicContact CG1-CD1 4.02Å; V415-I417 HydrophobicContact CG1-CG1 4.02Å; I417-L420 HydrophobicContact CB-CD1 4.42Å; I417-L420 HydrophobicContact CG2-CD2 4.1Å; I417-L420 HydrophobicContact CG2-CG 4.36Å; I417-L420 VanDerWaalsContact O-CD1 3.24Å; I417-L420 WeakPolarHBondContact O-CD1 3.3Å; I417-L420 WeakPolarHBondContact O-CG 3.33Å
418	E	89.8	Confident	93.6	Very high	91 Å²	91	26.5 Å²	26.5	43%	0.425	17%	0.168	S	C	.	.	B	Isolated β-bridge	trans	-94.9	168.8	-178.9	-66.4	177.2	-170.2	0	0	111.6	H155 I156 V157 C158 L420	H155-E418 IonicContact CE1-OE1 3.63Å; H155-E418 IonicContact CG-OE1 3.78Å; H155-E418 IonicContact ND1-OE1 2.93Å; H155-E418 PolarHBondContact ND1-OE1 3.32Å; H155-E418 IonicContact ND1-OE2 2.76Å; I156-E418 PolarHBondContact O-N 3.47Å; V157-E418 HydrophobicContact CG2-CB 4.22Å; C158-E418 PolarHBondContact N-O 3.48Å; E418-L420 VanDerWaalsContact C-N 3.3Å; E418-L420 PolarHBondContact O-N 3.39Å
419	G	89.7	Confident	93.5	Very high	34 Å²	34	26.9 Å²	26.9	35%	0.351	17%	0.17	S	C	.	.	S	Bend	trans	76	14	-178.8	0	0	0	0	0	114.6
420	L	94.3	Very high	93.5	Very high	2 Å²	2	31.5 Å²	31.5	1%	0.01	20%	0.195	C	C	.	.	H	α-helix	trans	-80.3	-19.6	-178.3	-60.5	176.6	0	0	0	114	C158 L409 L412 A413 I417 E418 L423 A424 W431	C158-L420 HydrophobicContact CB-CD2 4.16Å; L409-L420 HydrophobicContact CD2-CD2 4.31Å; L412-L420 HydrophobicContact CB-CD1 3.75Å; L412-L420 HydrophobicContact CB-CD2 4.07Å; L412-L420 HydrophobicContact CD1-CD2 4.04Å; A413-L420 HydrophobicContact CB-CD1 3.8Å; I417-L420 HydrophobicContact CB-CD1 4.42Å; I417-L420 HydrophobicContact CG2-CD2 4.1Å; I417-L420 HydrophobicContact CG2-CG 4.36Å; I417-L420 VanDerWaalsContact O-CD1 3.24Å; I417-L420 WeakPolarHBondContact O-CD1 3.3Å; I417-L420 WeakPolarHBondContact O-CG 3.33Å; E418-L420 VanDerWaalsContact C-N 3.3Å; E418-L420 PolarHBondContact O-N 3.39Å; L420-L423 HydrophobicContact CD2-CD2 4.11Å; L420-L423 WeakPolarHBondContact O-CB 3.24Å; L420-L423 PolarHBondContact O-N 2.89Å; L420-A424 PolarHBondContact O-N 3.1Å; L420-W431 HydrophobicContact CB-CH2 3.8Å; L420-W431 HydrophobicContact CB-CZ3 3.61Å
421	L	94.6	Very high	93.4	Very high	85 Å²	85	35.2 Å²	35.2	45%	0.445	21%	0.209	S	C	.	.	H	α-helix	trans	-63.2	-52.5	-178.5	176	69.1	0	0	0	112.1	L423 A424 D425 W431	L421-L423 PolarHBondContact O-N 3.12Å; L421-A424 WeakPolarHBondContact O-CB 3.34Å; L421-A424 PolarHBondContact O-N 3.42Å; L421-A424 VanDerWaalsContact O-N 3.12Å; L421-D425 PolarHBondContact O-N 3.48Å; L421-D425 VanDerWaalsContact O-N 3.09Å; L421-W431 HydrophobicContact CB-CD2 4.45Å; L421-W431 HydrophobicContact CB-CE3 4.25Å; L421-W431 HydrophobicContact CB-CZ3 4.44Å; L421-W431 HydrophobicContact CD1-CB 3.57Å; L421-W431 HydrophobicContact CD1-CD2 3.75Å; L421-W431 HydrophobicContact CD1-CE3 4.01Å; L421-W431 HydrophobicContact CD1-CG 3.55Å
422	P	94.5	Very high	93.5	Very high	66 Å²	66	41.4 Å²	41.4	43%	0.429	24%	0.236	S	C	.	.	H	α-helix	trans	-61	-29.3	174.4	-22.7	33.8	0	0	0	113.6	L160 L426	L160-P422 HydrophobicContact CD2-CB 4.23Å; P422-L426 WeakPolarHBondContact O-CB 3.35Å; P422-L426 PolarHBondContact O-N 3.43Å
423	L	95	Very high	93.6	Very high	2 Å²	2	44.5 Å²	44.5	1%	0.01	25%	0.253	C	S	.	.	H	α-helix	trans	-71.1	-39	177.2	-176.3	63.6	0	0	0	111.7	L160 L163 F314 L409 L420 L421 L426 C427	L160-L423 HydrophobicContact CD1-CD1 3.83Å; L163-L423 HydrophobicContact CD1-CD1 4.34Å; L163-L423 HydrophobicContact CD2-CD1 3.38Å; F314-L423 HydrophobicContact CD1-CD1 4.26Å; F314-L423 HydrophobicContact CD1-CD2 3.7Å; F314-L423 HydrophobicContact CD1-CG 4.44Å; F314-L423 HydrophobicContact CD2-CD2 4.5Å; F314-L423 HydrophobicContact CE1-CD1 3.78Å; F314-L423 HydrophobicContact CE1-CD2 3.77Å; F314-L423 HydrophobicContact CE1-CG 4.04Å; F314-L423 HydrophobicContact CG-CD2 4.1Å; F314-L423 HydrophobicContact CZ-CD1 4.47Å; F314-L423 HydrophobicContact CZ-CD2 4.2Å; F314-L423 HydrophobicContact CZ-CG 4.37Å; L409-L423 HydrophobicContact CD2-CB 4.49Å; L409-L423 HydrophobicContact CD2-CD2 3.52Å; L409-L423 HydrophobicContact CD2-CG 3.85Å; L420-L423 HydrophobicContact CD2-CD2 4.11Å; L420-L423 WeakPolarHBondContact O-CB 3.24Å; L420-L423 PolarHBondContact O-N 2.89Å; L421-L423 PolarHBondContact O-N 3.12Å; L423-L426 PolarHBondContact O-N 3.33Å; L423-C427 PolarHBondContact O-N 3.3Å; L423-C427 VanDerWaalsContact O-N 3.09Å; L423-C427 PolarHBondContact O-SG 2.96Å
424	A	96.3	Very high	93.8	Very high	0 Å²	0	44.4 Å²	44.4	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-63.1	-43.6	173.4	0	0	0	0	0	111	L409 L420 L421 L426 C427 G428 V429 W431 V434	L409-A424 HydrophobicContact CD1-CB 4.01Å; L420-A424 PolarHBondContact O-N 3.1Å; L421-A424 WeakPolarHBondContact O-CB 3.34Å; L421-A424 PolarHBondContact O-N 3.42Å; L421-A424 VanDerWaalsContact O-N 3.12Å; A424-L426 PolarHBondContact O-N 2.78Å; A424-C427 CarbonylContact O-C 3.52Å; A424-C427 PolarHBondContact O-N 3.37Å; A424-C427 VanDerWaalsContact O-N 3.16Å; A424-G428 PolarHBondContact O-N 3.35Å; A424-G428 VanDerWaalsContact O-N 3.11Å; A424-V429 CarbonylContact C-O 3.5Å; A424-V429 PolarHBondContact O-N 3.37Å; A424-W431 HydrophobicContact CB-CE3 4.12Å; A424-V434 HydrophobicContact CB-CG2 4.21Å
425	D	95.9	Very high	94.1	Very high	108 Å²	108	51.1 Å²	51.1	58%	0.578	28%	0.277	S	S	*	.	H	α-helix	trans	-60.4	-44.6	175.4	-64.8	-30.5	0	0	0	111.5	L421 C427 G428	L421-D425 PolarHBondContact O-N 3.48Å; L421-D425 VanDerWaalsContact O-N 3.09Å; D425-C427 VanDerWaalsContact C-N 3.26Å; D425-C427 PolarHBondContact O-N 3.28Å; D425-G428 PolarHBondContact O-N 2.89Å; D425-G428 VanDerWaalsContact O-N 3.08Å
426	L	95.3	Very high	94.5	Very high	64 Å²	64	53.1 Å²	53.1	34%	0.335	29%	0.286	S	S	.	.	H	α-helix	trans	-60.5	-35.6	176.1	-177.8	65.9	0	0	0	112.4	L160 L163 L168 P422 L423 A424 G428	L160-L426 HydrophobicContact CD1-CD2 3.59Å; L160-L426 HydrophobicContact CG-CD2 4.44Å; L163-L426 HydrophobicContact CD2-CD2 3.9Å; L168-L426 HydrophobicContact CD2-CD2 3.71Å; L168-L426 HydrophobicContact CD2-CG 4.12Å; P422-L426 WeakPolarHBondContact O-CB 3.35Å; P422-L426 PolarHBondContact O-N 3.43Å; L423-L426 PolarHBondContact O-N 3.33Å; A424-L426 PolarHBondContact O-N 2.78Å; L426-G428 VanDerWaalsContact C-N 3.29Å
427	C	95.7	Very high	95	Very high	7 Å²	7	52.3 Å²	52.3	5%	0.047	28%	0.277	C	S	.	.	T	Hydrogen-bonded Turn	trans	-82.6	-4.1	178.7	-62.7	0	0	0	0	113.8	R403 V405 L423 A424 D425 V429	R403-C427 PolarHBondContact NH1-O 3.37Å; R403-C427 VanDerWaalsContact NH1-O 3.14Å; R403-C427 PolarHBondContact NH2-O 3.29Å; V405-C427 HydrophobicContact CG1-CB 3.71Å; L423-C427 PolarHBondContact O-N 3.3Å; L423-C427 VanDerWaalsContact O-N 3.09Å; L423-C427 PolarHBondContact O-SG 2.96Å; A424-C427 CarbonylContact O-C 3.52Å; A424-C427 PolarHBondContact O-N 3.37Å; A424-C427 VanDerWaalsContact O-N 3.16Å; D425-C427 VanDerWaalsContact C-N 3.26Å; D425-C427 PolarHBondContact O-N 3.28Å; C427-V429 HydrophobicContact CB-CG2 4.06Å
428	G	95.6	Very high	95.3	Very high	58 Å²	58	52.2 Å²	52.2	60%	0.598	28%	0.278	S	S	*	.	T	Hydrogen-bonded Turn	trans	62.7	40	-173.5	0	0	0	0	0	112.9	R403 A424 D425 L426	R403-G428 PolarHBondContact NH1-O 3.27Å; R403-G428 VanDerWaalsContact NH1-O 3.14Å; A424-G428 PolarHBondContact O-N 3.35Å; A424-G428 VanDerWaalsContact O-N 3.11Å; D425-G428 PolarHBondContact O-N 2.89Å; D425-G428 VanDerWaalsContact O-N 3.08Å; L426-G428 VanDerWaalsContact C-N 3.29Å
429	V	96.2	Very high	95.5	Very high	8 Å²	8	50.7 Å²	50.7	5%	0.048	27%	0.273	C	S	.	.			trans	-115.6	130.7	177.7	-179.1	0	0	0	0	108.9	V405 C406 A424 C427 W431 V434	V405-V429 HydrophobicContact CG1-CG2 4.38Å; C406-V429 HydrophobicContact CB-CG1 3.66Å; C406-V429 HydrophobicContact CB-CG2 4.45Å; A424-V429 CarbonylContact C-O 3.5Å; A424-V429 PolarHBondContact O-N 3.37Å; C427-V429 HydrophobicContact CB-CG2 4.06Å; V429-W431 PolarHBondContact O-N 2.84Å; V429-V434 HydrophobicContact CG1-CG2 3.74Å
430	D	96.2	Very high	95.8	Very high	97 Å²	97	49.5 Å²	49.5	52%	0.519	26%	0.258	S	S	.	.			trans	-66.7	133.9	175.9	-173.2	4.7	0	0	0	110.7	F432 D433 V434	D430-F432 PolarHBondContact O-N 2.88Å; D430-F432 PolarHBondContact OD1-N 3.16Å; D430-F432 WeakPolarHBondContact OD2-CB 3.28Å; D430-D433 WeakPolarHBondContact O-CB 3.26Å; D430-D433 PolarHBondContact O-N 3.02Å; D430-V434 PolarHBondContact O-N 3.35Å
431	W	95.5	Very high	95.8	Very high	79 Å²	79	49.5 Å²	49.5	30%	0.299	26%	0.258	S	S	.	.	H	α-helix	trans	-59.9	-29	175.8	-175.2	-112	0	0	0	112.5	L420 L421 A424 V429 D433 V434 R435	L420-W431 HydrophobicContact CB-CH2 3.8Å; L420-W431 HydrophobicContact CB-CZ3 3.61Å; L421-W431 HydrophobicContact CB-CD2 4.45Å; L421-W431 HydrophobicContact CB-CE3 4.25Å; L421-W431 HydrophobicContact CB-CZ3 4.44Å; L421-W431 HydrophobicContact CD1-CB 3.57Å; L421-W431 HydrophobicContact CD1-CD2 3.75Å; L421-W431 HydrophobicContact CD1-CE3 4.01Å; L421-W431 HydrophobicContact CD1-CG 3.55Å; A424-W431 HydrophobicContact CB-CE3 4.12Å; V429-W431 PolarHBondContact O-N 2.84Å; W431-D433 VanDerWaalsContact C-N 3.35Å; W431-V434 HydrophobicContact CE3-CB 4.11Å; W431-V434 HydrophobicContact CE3-CG1 4.11Å; W431-V434 HydrophobicContact CE3-CG2 4.44Å; W431-V434 HydrophobicContact CH2-CG1 4.47Å; W431-V434 HydrophobicContact CZ3-CB 4.4Å; W431-V434 HydrophobicContact CZ3-CG1 3.88Å; W431-V434 PolarHBondContact O-N 2.81Å; W431-R435 WeakPolarHBondContact O-CB 3.43Å; W431-R435 PolarHBondContact O-N 3.5Å
432	F	96.3	Very high	95.6	Very high	129 Å²	129	46 Å²	46	57%	0.566	24%	0.243	S	C	*	.	H	α-helix	trans	-60.1	-45	173.3	-176.9	-93.7	0	0	0	111.7	D430 R435 E436	D430-F432 PolarHBondContact O-N 2.88Å; D430-F432 PolarHBondContact OD1-N 3.16Å; D430-F432 WeakPolarHBondContact OD2-CB 3.28Å; F432-R435 PolarHBondContact O-N 3.33Å; F432-E436 PolarHBondContact O-N 2.98Å
433	D	96.6	Very high	95.5	Very high	66 Å²	66	48.5 Å²	48.5	35%	0.353	25%	0.249	S	C	.	.	H	α-helix	trans	-64.9	-41.2	178	-68.2	-26.9	0	0	0	111.2	F402 D430 W431 R435 E436 C437	F402-D433 HydrophobicContact CD1-CB 4.43Å; F402-D433 HydrophobicContact CE1-CB 4.46Å; D430-D433 WeakPolarHBondContact O-CB 3.26Å; D430-D433 PolarHBondContact O-N 3.02Å; W431-D433 VanDerWaalsContact C-N 3.35Å; D433-R435 VanDerWaalsContact C-N 3.28Å; D433-R435 PolarHBondContact O-N 2.88Å; D433-E436 PolarHBondContact O-N 3.36Å; D433-C437 VanDerWaalsContact O-CB 3.23Å; D433-C437 WeakPolarHBondContact O-CB 3.25Å; D433-C437 PolarHBondContact O-N 2.91Å
434	V	97.1	Very high	95.4	Very high	0 Å²	0	48.5 Å²	48.5	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-59	-42.1	174.9	178	0	0	0	0	110.7	L409 A413 A424 V429 D430 W431 C437 A438	L409-V434 HydrophobicContact CB-CG1 3.87Å; L409-V434 HydrophobicContact CB-CG2 4.05Å; L409-V434 HydrophobicContact CD1-CG2 4.13Å; A413-V434 HydrophobicContact CB-CG1 4.19Å; A424-V434 HydrophobicContact CB-CG2 4.21Å; V429-V434 HydrophobicContact CG1-CG2 3.74Å; D430-V434 PolarHBondContact O-N 3.35Å; W431-V434 HydrophobicContact CE3-CB 4.11Å; W431-V434 HydrophobicContact CE3-CG1 4.11Å; W431-V434 HydrophobicContact CE3-CG2 4.44Å; W431-V434 HydrophobicContact CH2-CG1 4.47Å; W431-V434 HydrophobicContact CZ3-CB 4.4Å; W431-V434 HydrophobicContact CZ3-CG1 3.88Å; W431-V434 PolarHBondContact O-N 2.81Å; V434-C437 PolarHBondContact O-N 3.1Å; V434-A438 WeakPolarHBondContact O-CB 3.02Å; V434-A438 PolarHBondContact O-N 3.1Å
435	R	96.2	Very high	95.1	Very high	153 Å²	153	49.9 Å²	49.9	58%	0.577	25%	0.254	S	S	*	.	H	α-helix	trans	-70.7	-39.9	178.4	-169.7	175.6	-178.1	-178.7	-0	112.5	W431 F432 D433 C437 N439	W431-R435 WeakPolarHBondContact O-CB 3.43Å; W431-R435 PolarHBondContact O-N 3.5Å; F432-R435 PolarHBondContact O-N 3.33Å; D433-R435 VanDerWaalsContact C-N 3.28Å; D433-R435 PolarHBondContact O-N 2.88Å; R435-C437 VanDerWaalsContact C-N 3.33Å; R435-N439 VanDerWaalsContact O-CG 3.26Å; R435-N439 PolarHBondContact O-N 3.41Å; R435-N439 VanDerWaalsContact O-N 3.09Å; R435-N439 PolarHBondContact O-ND2 3.35Å; R435-N439 VanDerWaalsContact O-ND2 3.14Å
436	E	96.7	Very high	94.7	Very high	42 Å²	42	47.9 Å²	47.9	20%	0.196	24%	0.241	C	C	.	.	H	α-helix	trans	-63.3	-41.9	173.8	-167.8	174.9	175.4	0	0	110.6	R39 F402 F432 D433 N439 L440	R39-E436 IonicContact NH2-OE1 3.92Å; R39-E436 PolarHBondContact NH2-OE1 3.2Å; R39-E436 IonicContact NH2-OE2 2.78Å; F402-E436 HydrophobicContact CE1-CB 4.26Å; F402-E436 HydrophobicContact CZ-CB 4.12Å; F402-E436 HydrophobicContact CZ-CG 4.03Å; F432-E436 PolarHBondContact O-N 2.98Å; D433-E436 PolarHBondContact O-N 3.36Å; E436-N439 PolarHBondContact O-N 3.39Å; E436-L440 PolarHBondContact O-N 3.3Å
437	C	97	Very high	94.2	Very high	0 Å²	0	50.1 Å²	50.1	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-62.2	-48.6	175.8	-171.1	0	0	0	0	111.9	F402 D433 V434 R435 N439 L440 V441	F402-C437 HydrophobicContact CD1-CB 4.04Å; F402-C437 HydrophobicContact CD2-CB 3.93Å; F402-C437 HydrophobicContact CE1-CB 4Å; F402-C437 HydrophobicContact CE2-CB 3.89Å; F402-C437 HydrophobicContact CG-CB 4.01Å; F402-C437 HydrophobicContact CZ-CB 3.92Å; D433-C437 VanDerWaalsContact O-CB 3.23Å; D433-C437 WeakPolarHBondContact O-CB 3.25Å; D433-C437 PolarHBondContact O-N 2.91Å; V434-C437 PolarHBondContact O-N 3.1Å; R435-C437 VanDerWaalsContact C-N 3.33Å; C437-N439 VanDerWaalsContact C-N 3.3Å; C437-N439 PolarHBondContact O-N 3.21Å; C437-L440 WeakPolarHBondContact O-CB 3.45Å; C437-L440 PolarHBondContact O-N 3.02Å; C437-V441 WeakPolarHBondContact O-CG2 3.49Å; C437-V441 PolarHBondContact O-N 3.08Å
438	A	95.8	Very high	93.5	Very high	6 Å²	6	53.4 Å²	53.4	5%	0.05	27%	0.265	C	S	.	.	H	α-helix	trans	-56.3	-44	176.4	0	0	0	0	0	112	G410 A413 Q414 V434 L440 V441 G442	G410-A438 WeakPolarHBondContact O-CA 3.47Å; G410-A438 VanDerWaalsContact O-CB 3.3Å; G410-A438 WeakPolarHBondContact O-CB 3.28Å; A413-A438 HydrophobicContact CB-CB 4.12Å; Q414-A438 HydrophobicContact CB-CB 4.25Å; Q414-A438 PolarHBondContact OE1-O 3.45Å; V434-A438 WeakPolarHBondContact O-CB 3.02Å; V434-A438 PolarHBondContact O-N 3.1Å; A438-L440 PolarHBondContact O-N 2.94Å; A438-V441 PolarHBondContact O-N 2.76Å; A438-G442 PolarHBondContact O-N 3.36Å
439	N	95.5	Very high	92.4	Very high	59 Å²	59	57.3 Å²	57.3	32%	0.316	26%	0.263	S	S	.	.	H	α-helix	trans	-64.4	-37.5	176.2	-71.4	-31.4	0	0	0	112.7	R435 E436 C437 G442 Q443	R435-N439 VanDerWaalsContact O-CG 3.26Å; R435-N439 PolarHBondContact O-N 3.41Å; R435-N439 VanDerWaalsContact O-N 3.09Å; R435-N439 PolarHBondContact O-ND2 3.35Å; R435-N439 VanDerWaalsContact O-ND2 3.14Å; E436-N439 PolarHBondContact O-N 3.39Å; C437-N439 VanDerWaalsContact C-N 3.3Å; C437-N439 PolarHBondContact O-N 3.21Å; N439-G442 PolarHBondContact O-N 2.7Å; N439-Q443 WeakPolarHBondContact O-CG 3.32Å; N439-Q443 PolarHBondContact O-N 3Å; N439-Q443 VanDerWaalsContact O-N 3.08Å; N439-Q443 PolarHBondContact O-NE2 3.19Å
440	L	95.5	Very high	90.7	Very high	9 Å²	9	64 Å²	64	5%	0.047	29%	0.287	C	S	.	.	H	α-helix	trans	-65.8	-47.8	175.3	178	64.3	0	0	0	110.7	E398 V399 F402 E436 C437 A438 G442 Q443 L444	E398-L440 HydrophobicContact CB-CD2 4.12Å; V399-L440 HydrophobicContact CG1-CD2 4.09Å; F402-L440 HydrophobicContact CD2-CD2 4.48Å; F402-L440 HydrophobicContact CE2-CD2 3.79Å; E436-L440 PolarHBondContact O-N 3.3Å; C437-L440 WeakPolarHBondContact O-CB 3.45Å; C437-L440 PolarHBondContact O-N 3.02Å; A438-L440 PolarHBondContact O-N 2.94Å; L440-G442 VanDerWaalsContact C-N 3.25Å; L440-G442 PolarHBondContact O-N 2.98Å; L440-Q443 WeakPolarHBondContact O-CB 3.14Å; L440-Q443 PolarHBondContact O-N 2.82Å; L440-L444 HydrophobicContact CD1-CD1 4.36Å; L440-L444 HydrophobicContact CD1-CG 4.21Å; L440-L444 HydrophobicContact CG-CD1 4.06Å; L440-L444 HydrophobicContact CG-CG 4.32Å; L440-L444 WeakPolarHBondContact O-CG 3.43Å; L440-L444 PolarHBondContact O-N 2.96Å
441	V	94.1	Very high	88.1	Confident	2 Å²	2	66.4 Å²	66.4	1%	0.012	30%	0.3	C	S	.	.	H	α-helix	trans	-56.4	-42.5	176.2	173.5	0	0	0	0	110.6	L389 A393 L407 I411 Q414 C437 A438 L444 Y445	L389-V441 HydrophobicContact CB-CG1 4.34Å; L389-V441 HydrophobicContact CD2-CG1 4.22Å; A393-V441 HydrophobicContact CB-CG2 4.1Å; L407-V441 HydrophobicContact CD1-CG2 4.12Å; I411-V441 HydrophobicContact CG1-CG1 4.18Å; I411-V441 HydrophobicContact CG1-CG2 4.04Å; Q414-V441 HydrophobicContact CG-CG1 4.35Å; C437-V441 WeakPolarHBondContact O-CG2 3.49Å; C437-V441 PolarHBondContact O-N 3.08Å; A438-V441 PolarHBondContact O-N 2.76Å; V441-L444 PolarHBondContact O-N 3.31Å; V441-Y445 WeakPolarHBondContact O-CB 3.39Å; V441-Y445 PolarHBondContact O-N 2.98Å
442	G	91	Very high	85.4	Confident	12 Å²	12	67.8 Å²	67.8	12%	0.124	32%	0.319	C	S	.	.	H	α-helix	trans	-60.6	-42.6	174.3	0	0	0	0	0	113.7	Q414 A438 N439 L440 Y445 E446	Q414-G442 VanDerWaalsContact NE2-CA 3.31Å; A438-G442 PolarHBondContact O-N 3.36Å; N439-G442 PolarHBondContact O-N 2.7Å; L440-G442 VanDerWaalsContact C-N 3.25Å; L440-G442 PolarHBondContact O-N 2.98Å; G442-Y445 PolarHBondContact O-N 3.32Å; G442-E446 PolarHBondContact O-N 2.73Å; G442-E446 VanDerWaalsContact O-N 3.09Å
443	Q	92.8	Very high	82.4	Confident	117 Å²	117	67 Å²	67	55%	0.547	33%	0.327	S	S	.	.	H	α-helix	trans	-65.8	-45.7	176.2	-73.8	165.3	68.3	0	0	112	N439 L440 Y445 E446 L447	N439-Q443 WeakPolarHBondContact O-CG 3.32Å; N439-Q443 PolarHBondContact O-N 3Å; N439-Q443 VanDerWaalsContact O-N 3.08Å; N439-Q443 PolarHBondContact O-NE2 3.19Å; L440-Q443 WeakPolarHBondContact O-CB 3.14Å; L440-Q443 PolarHBondContact O-N 2.82Å; Q443-Y445 VanDerWaalsContact C-N 3.29Å; Q443-Y445 PolarHBondContact O-N 2.78Å; Q443-E446 PolarHBondContact O-N 3.24Å; Q443-L447 VanDerWaalsContact O-CG 3.3Å; Q443-L447 WeakPolarHBondContact O-CG 3.34Å; Q443-L447 PolarHBondContact O-N 3.19Å
444	L	92.5	Very high	79.4	Confident	2 Å²	2	69.4 Å²	69.4	1%	0.01	35%	0.346	C	S	.	.	H	α-helix	trans	-62.1	-39.3	176.9	-67.2	176.6	0	0	0	111.4	I392 V399 L440 V441 L447 Y448	I392-L444 HydrophobicContact CG2-CB 4.33Å; V399-L444 HydrophobicContact CG1-CD1 3.71Å; L440-L444 HydrophobicContact CD1-CD1 4.36Å; L440-L444 HydrophobicContact CD1-CG 4.21Å; L440-L444 HydrophobicContact CG-CD1 4.06Å; L440-L444 HydrophobicContact CG-CG 4.32Å; L440-L444 WeakPolarHBondContact O-CG 3.43Å; L440-L444 PolarHBondContact O-N 2.96Å; V441-L444 PolarHBondContact O-N 3.31Å; L444-L447 HydrophobicContact CD2-CD1 4.48Å; L444-L447 PolarHBondContact O-N 2.99Å; L444-Y448 HydrophobicContact CB-CD2 4.4Å; L444-Y448 HydrophobicContact CD2-CE2 4.14Å; L444-Y448 VanDerWaalsContact O-CD2 3.3Å; L444-Y448 WeakPolarHBondContact O-CD2 3.36Å; L444-Y448 PolarHBondContact O-N 2.88Å
445	Y	88.5	Confident	76.6	Confident	30 Å²	30	74.8 Å²	74.8	12%	0.118	38%	0.384	C	S	.	.	H	α-helix	trans	-59.7	-48.3	174.2	-177.4	-94	0	0	0	111.9	R385 L389 I392 V441 G442 Q443 L447 Y449	R385-Y445 VanDerWaalsContact NH1-CE2 3.25Å; R385-Y445 PolarHBondContact NH1-OH 3.5Å; L389-Y445 HydrophobicContact CD2-CD2 3.47Å; L389-Y445 VanDerWaalsContact CD2-CD2 3.47Å; L389-Y445 HydrophobicContact CD2-CE2 4.13Å; L389-Y445 HydrophobicContact CD2-CG 3.94Å; I392-Y445 HydrophobicContact CD1-CD2 3.59Å; I392-Y445 HydrophobicContact CD1-CE2 3.92Å; V441-Y445 WeakPolarHBondContact O-CB 3.39Å; V441-Y445 PolarHBondContact O-N 2.98Å; G442-Y445 PolarHBondContact O-N 3.32Å; Q443-Y445 VanDerWaalsContact C-N 3.29Å; Q443-Y445 PolarHBondContact O-N 2.78Å; Y445-L447 VanDerWaalsContact C-N 3.34Å; Y445-L447 PolarHBondContact O-N 2.73Å; Y445-Y449 HydrophobicContact CE1-CD1 4.16Å; Y445-Y449 HydrophobicContact CE1-CG 4.32Å; Y445-Y449 HydrophobicContact CE2-CD1 4.23Å; Y445-Y449 HydrophobicContact CE2-CD2 4.02Å; Y445-Y449 AromaticContact CE2-CG 3.8Å; Y445-Y449 HydrophobicContact CE2-CG 3.8Å; Y445-Y449 AromaticContact CZ-CD1 3.62Å; Y445-Y449 AromaticContact CZ-CG 3.66Å; Y445-Y449 WeakPolarHBondContact O-CA 3.39Å; Y445-Y449 WeakPolarHBondContact O-CB 3.49Å; Y445-Y449 PolarHBondContact O-N 2.91Å; Y445-Y449 VanDerWaalsContact OH-CD1 3.24Å; Y445-Y449 WeakPolarHBondContact OH-CD1 3.32Å; Y445-Y449 WeakPolarHBondContact OH-CE1 3.4Å
446	E	87.7	Confident	73.8	Confident	66 Å²	66	72.7 Å²	72.7	31%	0.308	39%	0.392	S	S	.	.	H	α-helix	trans	-63.4	-39.4	176.4	-69	-68.2	136.6	0	0	111.7	G442 Q443 R450	G442-E446 PolarHBondContact O-N 2.73Å; G442-E446 VanDerWaalsContact O-N 3.09Å; Q443-E446 PolarHBondContact O-N 3.24Å; E446-R450 WeakPolarHBondContact O-CB 3.33Å; E446-R450 PolarHBondContact O-N 2.98Å; E446-R450 VanDerWaalsContact O-N 3.16Å; E446-R450 IonicContact OE1-NH1 3.86Å; E446-R450 VanDerWaalsContact OE2-CD 3.23Å; E446-R450 WeakPolarHBondContact OE2-CD 3.36Å; E446-R450 WeakPolarHBondContact OE2-CG 3.44Å; E446-R450 IonicContact OE2-NE 2.78Å; E446-R450 IonicContact OE2-NH1 3.58Å; E446-R450 PolarHBondContact OE2-NH1 3Å
447	L	85.5	Confident	70.9	Confident	110 Å²	110	80.4 Å²	80.4	58%	0.576	42%	0.42	S	S	*	.	H	α-helix	trans	-66.1	-41.3	179.8	-73.4	170.9	0	0	0	113.9	I45 Q443 L444 Y445	I45-L447 HydrophobicContact CD1-CD1 4.26Å; Q443-L447 VanDerWaalsContact O-CG 3.3Å; Q443-L447 WeakPolarHBondContact O-CG 3.34Å; Q443-L447 PolarHBondContact O-N 3.19Å; L444-L447 HydrophobicContact CD2-CD1 4.48Å; L444-L447 PolarHBondContact O-N 2.99Å; Y445-L447 VanDerWaalsContact C-N 3.34Å; Y445-L447 PolarHBondContact O-N 2.73Å
448	Y	81	Confident	67.9	Low	76 Å²	76	91.7 Å²	91.7	30%	0.298	46%	0.462	S	S	.	.	H	α-helix	trans	-95	-19.3	-175.2	-72.3	-64.2	0	0	0	114.1	H206 I392 C395 L444	H206-Y448 AromaticContact CE1-CD1 3.55Å; H206-Y448 AromaticContact CE1-CE1 3.9Å; H206-Y448 AromaticContact ND1-CD1 3.48Å; H206-Y448 WeakPolarHBondContact ND1-CD1 3.36Å; H206-Y448 AromaticContact ND1-CE1 3.45Å; H206-Y448 WeakPolarHBondContact ND1-CE1 3.4Å; I392-Y448 HydrophobicContact CG2-CD2 3.73Å; I392-Y448 HydrophobicContact CG2-CG 4.25Å; C395-Y448 HydrophobicContact CB-CE2 4.12Å; L444-Y448 HydrophobicContact CB-CD2 4.4Å; L444-Y448 HydrophobicContact CD2-CE2 4.14Å; L444-Y448 VanDerWaalsContact O-CD2 3.3Å; L444-Y448 WeakPolarHBondContact O-CD2 3.36Å; L444-Y448 PolarHBondContact O-N 2.88Å
449	Y	73	Confident	64.9	Low	140 Å²	140	101.5 Å²	101.5	55%	0.549	50%	0.498	S	S	.	.	H	α-helix	trans	-113.8	-33.6	-172.5	-160.2	-86.1	0	0	0	114.1	I392 Y445	I392-Y449 HydrophobicContact CD1-CD2 4.17Å; Y445-Y449 HydrophobicContact CE1-CD1 4.16Å; Y445-Y449 HydrophobicContact CE1-CG 4.32Å; Y445-Y449 HydrophobicContact CE2-CD1 4.23Å; Y445-Y449 HydrophobicContact CE2-CD2 4.02Å; Y445-Y449 AromaticContact CE2-CG 3.8Å; Y445-Y449 HydrophobicContact CE2-CG 3.8Å; Y445-Y449 AromaticContact CZ-CD1 3.62Å; Y445-Y449 AromaticContact CZ-CG 3.66Å; Y445-Y449 WeakPolarHBondContact O-CA 3.39Å; Y445-Y449 WeakPolarHBondContact O-CB 3.49Å; Y445-Y449 PolarHBondContact O-N 2.91Å; Y445-Y449 VanDerWaalsContact OH-CD1 3.24Å; Y445-Y449 WeakPolarHBondContact OH-CD1 3.32Å; Y445-Y449 WeakPolarHBondContact OH-CE1 3.4Å
450	R	60.7	Low	62.2	Low	148 Å²	148	102.5 Å²	102.5	56%	0.558	51%	0.514	S	S	*	.	S	Bend	trans	-92.2	118.8	170.5	-71.8	-140.1	169.3	144.4	-12	107	E446	E446-R450 WeakPolarHBondContact O-CB 3.33Å; E446-R450 PolarHBondContact O-N 2.98Å; E446-R450 VanDerWaalsContact O-N 3.16Å; E446-R450 IonicContact OE1-NH1 3.86Å; E446-R450 VanDerWaalsContact OE2-CD 3.23Å; E446-R450 WeakPolarHBondContact OE2-CD 3.36Å; E446-R450 WeakPolarHBondContact OE2-CG 3.44Å; E446-R450 IonicContact OE2-NE 2.78Å; E446-R450 IonicContact OE2-NH1 3.58Å; E446-R450 PolarHBondContact OE2-NH1 3Å
451	D	40.3	Very low	59.3	Low	148 Å²	148	105.7 Å²	105.7	79%	0.791	55%	0.549	S	S	*	.			trans	-26.5	141.9	-177.3	-66.5	-52.1	0	0	0	114.7
452	P	39.5	Very low	56.6	Low	108 Å²	108	112.8 Å²	112.8	70%	0.701	59%	0.586	S	S	*	*			trans	-49.1	132.7	173.3	21.3	-31.3	0	0	0	108.3
453	P	32.3	Very low	54	Low	112 Å²	112	121.5 Å²	121.5	73%	0.727	62%	0.621	S	S	*	*			trans	-49.2	135.6	-171.7	19.9	-32.5	0	0	0	108.1	S455	P453-S455 PolarHBondContact O-N 3.46Å
454	P	34	Very low	51.4	Low	118 Å²	118	122.8 Å²	122.8	77%	0.766	64%	0.637	S	S	*	*			trans	-53	109.4	-175.1	21	-32	0	0	0	107	S456	P454-S456 PolarHBondContact O-N 2.74Å
455	S	38.9	Very low	48.5	Very low	112 Å²	112	128 Å²	128	78%	0.783	67%	0.669	S	S	*	*			trans	-51.1	115.4	175.1	56.1	0	0	0	0	104.9	P453 R457	P453-S455 PolarHBondContact O-N 3.46Å; S455-R457 PolarHBondContact O-N 3.43Å; S455-R457 VanDerWaalsContact O-N 3.16Å
456	S	38.3	Very low	46	Very low	109 Å²	109	138.5 Å²	138.5	76%	0.762	71%	0.708	S	S	*	*			trans	-10.2	110.1	177.2	167.9	0	0	0	0	112.2	P454 R458	P454-S456 PolarHBondContact O-N 2.74Å; S456-R458 VanDerWaalsContact C-N 3.33Å; S456-R458 PolarHBondContact O-N 2.89Å
457	R	33.9	Very low	43.3	Very low	204 Å²	204	145.9 Å²	145.9	77%	0.77	73%	0.733	S	S	*	*			trans	-44.6	95	174.7	-78.4	178	178.8	-179.7	-0.8	110.2	S455	S455-R457 PolarHBondContact O-N 3.43Å; S455-R457 VanDerWaalsContact O-N 3.16Å
458	R	35.3	Very low	40.9	Very low	237 Å²	237	149.3 Å²	149.3	89%	0.894	75%	0.747	S	S	*	*			trans	-99.5	94.3	135.8	-69.9	-160	-157	-152.5	7	106.2	S456 A460	S456-R458 VanDerWaalsContact C-N 3.33Å; S456-R458 PolarHBondContact O-N 2.89Å; R458-A460 PolarHBondContact O-N 3.07Å
459	R	32	Very low	38.7	Very low	213 Å²	213	155.6 Å²	155.6	80%	0.804	78%	0.776	S	S	*	*			trans	-59.8	86	171.9	-162.1	-170.2	-60.3	-143.5	6.4	107.8
460	A	39.2	Very low	36.7	Very low	79 Å²	79	159.5 Å²	159.5	65%	0.653	79%	0.789	S	S	*	*			trans	-114	100.3	163.5	0	0	0	0	0	106.3	R458 L462	R458-A460 PolarHBondContact O-N 3.07Å; A460-L462 PolarHBondContact O-N 3.24Å; A460-L462 VanDerWaalsContact O-N 3.15Å
461	G	34.8	Very low	35.7	Very low	76 Å²	76	158.5 Å²	158.5	78%	0.784	80%	0.799	S	S	*	*			trans	-61.4	114.7	174.4	0	0	0	0	0	109.3
462	L	38	Very low	35.3	Very low	151 Å²	151	154.2 Å²	154.2	79%	0.791	79%	0.79	S	S	*	*			trans	-118.7	110.2	160.6	-98.3	131.9	0	0	0	106.7	A460 V464	A460-L462 PolarHBondContact O-N 3.24Å; A460-L462 VanDerWaalsContact O-N 3.15Å; L462-V464 PolarHBondContact O-N 2.86Å
463	F	35.2	Very low	34.8	Very low	196 Å²	196	159.8 Å²	159.8	86%	0.86	80%	0.799	S	S	*	*			trans	-48.5	112.5	164.5	-73.4	-89.8	0	0	0	108.3	T465	F463-T465 PolarHBondContact O-N 2.96Å
464	V	38.3	Very low	34.9	Very low	143 Å²	143	159.4 Å²	159.4	87%	0.867	80%	0.799	S	S	*	*			trans	-71.5	84.8	174.3	-179.1	0	0	0	0	107.1	L462	L462-V464 PolarHBondContact O-N 2.86Å
465	T	31.9	Very low	34.9	Very low	112 Å²	112	158.3 Å²	158.3	69%	0.687	79%	0.794	S	S	*	*			trans	-69.3	131.6	159.2	56	0	0	0	0	107.2	F463 R467	F463-T465 PolarHBondContact O-N 2.96Å; T465-R467 PolarHBondContact O-N 2.82Å
466	R	35.5	Very low	34.8	Very low	251 Å²	251	157.9 Å²	157.9	95%	0.947	79%	0.789	S	S	*	*	S	Bend	trans	-69.6	54.1	-170.5	-160.6	-175.9	-171.7	-146.2	3.8	113.1
467	R	32.1	Very low	34.7	Very low	221 Å²	221	158.3 Å²	158.3	83%	0.834	79%	0.787	S	S	*	*			trans	-141.8	121.7	176.7	-69.1	-173.2	179.4	-178.7	0.3	109.8	T465	T465-R467 PolarHBondContact O-N 2.82Å
468	Q	34.8	Very low	34.6	Very low	182 Å²	182	153.8 Å²	153.8	85%	0.85	78%	0.784	S	S	*	*			trans	118.8	53	163.4	-61.8	177.2	-9.2	0	0	116.3	R470	Q468-R470 VanDerWaalsContact C-N 3.34Å
469	F	35.5	Very low	34.7	Very low	208 Å²	208	144.3 Å²	144.3	91%	0.912	75%	0.751	S	S	*	*			trans	-96.6	70.2	136	-79.9	-83.3	0	0	0	108
470	R	30.3	Very low	35.1	Very low	221 Å²	221	140.4 Å²	140.4	83%	0.834	75%	0.746	S	S	*	*			trans	-100.8	70.8	161.6	-116.5	-171.9	-169.1	-118.7	3.9	106.3	Q468 G472	Q468-R470 VanDerWaalsContact C-N 3.34Å; R470-G472 PolarHBondContact O-N 3.06Å
471	V	40.7	Very low	35	Very low	127 Å²	127	141.7 Å²	141.7	77%	0.77	75%	0.746	S	S	*	*			trans	-70.1	119.4	162.7	179.6	0	0	0	0	105	Y473	V471-Y473 PolarHBondContact O-N 3.11Å
472	G	30.2	Very low	35.3	Very low	58 Å²	58	141.2 Å²	141.2	60%	0.598	72%	0.724	S	S	*	*			trans	-53.5	137.6	-169.7	0	0	0	0	0	112	R470 S474	R470-G472 PolarHBondContact O-N 3.06Å; G472-S474 PolarHBondContact O-N 2.97Å
473	Y	29.6	Very low	35.3	Very low	225 Å²	225	137.7 Å²	137.7	88%	0.882	71%	0.713	S	S	*	*			trans	-59.1	85.5	162.2	-66.5	-92.3	0	0	0	108.4	V471 S475	V471-Y473 PolarHBondContact O-N 3.11Å; Y473-S475 PolarHBondContact O-N 3.24Å
474	S	35.4	Very low	35.5	Very low	104 Å²	104	136.3 Å²	136.3	73%	0.727	71%	0.709	S	S	*	*			trans	-79.9	105.2	146.6	53.7	0	0	0	0	104.7	G472	G472-S474 PolarHBondContact O-N 2.97Å
475	S	34.1	Very low	35.4	Very low	95 Å²	95	135.4 Å²	135.4	66%	0.664	70%	0.699	S	S	*	*			trans	-42	137	165.9	48.1	0	0	0	0	109.3	Y473 T477	Y473-S475 PolarHBondContact O-N 3.24Å; S475-T477 PolarHBondContact O-N 3.02Å
476	P	35.5	Very low	35.7	Very low	103 Å²	103	138.9 Å²	138.9	67%	0.669	70%	0.701	S	S	*	*	P	Polyproline II helix	trans	-53.6	117.3	175.9	-17.7	28.1	0	0	0	107.9	P478	P476-P478 WeakPolarHBondContact O-CD 3.31Å
477	T	36	Very low	35.7	Very low	118 Å²	118	135.1 Å²	135.1	72%	0.724	69%	0.694	S	S	*	*	P	Polyproline II helix	trans	-62.9	119.7	163.8	39.4	0	0	0	0	105.7	S475 L479	S475-T477 PolarHBondContact O-N 3.02Å; T477-L479 PolarHBondContact O-N 3.03Å
478	P	32.6	Very low	35.7	Very low	109 Å²	109	129.7 Å²	129.7	71%	0.708	69%	0.688	S	S	*	*	P	Polyproline II helix	trans	-48.9	136.2	175.6	-24	32.7	0	0	0	109.2	P476 D480	P476-P478 WeakPolarHBondContact O-CD 3.31Å; P478-D480 VanDerWaalsContact C-N 3.34Å; P478-D480 PolarHBondContact O-N 2.91Å
479	L	36.8	Very low	35.9	Very low	38 Å²	38	127.1 Å²	127.1	20%	0.199	68%	0.684	C	S	.	*			trans	-63	101.5	174.1	-66.7	167.1	0	0	0	106.5	Y243 D286 T477 T481	Y243-L479 HydrophobicContact CD1-CD2 4.08Å; Y243-L479 HydrophobicContact CE1-CD2 3.76Å; D286-L479 HydrophobicContact CB-CD1 3.82Å; T477-L479 PolarHBondContact O-N 3.03Å; L479-T481 PolarHBondContact O-N 3.38Å
480	D	39.7	Very low	36.1	Very low	132 Å²	132	125.8 Å²	125.8	71%	0.706	68%	0.681	S	S	*	*			trans	-51.4	121.6	167.1	-78.1	-29	0	0	0	106.5	Y243 P478 I482	Y243-D480 PolarHBondContact OH-O 2.72Å; P478-D480 VanDerWaalsContact C-N 3.34Å; P478-D480 PolarHBondContact O-N 2.91Å; D480-I482 PolarHBondContact O-N 3.39Å
481	T	38.9	Very low	36.5	Very low	105 Å²	105	124 Å²	124	64%	0.644	68%	0.682	S	S	*	*			trans	-33.8	122.6	179.4	35	0	0	0	0	109	L479 S483	L479-T481 PolarHBondContact O-N 3.38Å; T481-S483 PolarHBondContact O-N 3.17Å
482	I	41.2	Very low	36.6	Very low	66 Å²	66	125 Å²	125	34%	0.338	68%	0.683	S	S	.	*			trans	-51.8	99.9	168.2	-63	164.6	0	0	0	105.3	Y243 M290 D480 E484	Y243-I482 HydrophobicContact CE1-CD1 4.19Å; Y243-I482 HydrophobicContact CE1-CG1 3.91Å; Y243-I482 HydrophobicContact CE2-CG1 4.03Å; M290-I482 HydrophobicContact CE-CD1 3.8Å; D480-I482 PolarHBondContact O-N 3.39Å; I482-E484 PolarHBondContact O-N 3.34Å
483	S	37.3	Very low	37	Very low	78 Å²	78	129.3 Å²	129.3	55%	0.545	69%	0.687	S	S	.	*			trans	-64.5	118.8	165.6	49.8	0	0	0	0	104.4	T481 D485	T481-S483 PolarHBondContact O-N 3.17Å; S483-D485 PolarHBondContact O-N 2.76Å; S483-D485 PolarHBondContact OG-OD1 3.28Å
484	E	39.6	Very low	38.2	Very low	166 Å²	166	128.5 Å²	128.5	78%	0.776	68%	0.683	S	S	*	*			trans	-60.7	99.4	162.7	-67.4	175.6	174.2	0	0	105	I482 Y486	I482-E484 PolarHBondContact O-N 3.34Å; E484-Y486 PolarHBondContact O-N 3.07Å
485	D	36.1	Very low	38.6	Very low	124 Å²	124	131 Å²	131	66%	0.663	69%	0.687	S	S	*	*			trans	-67.8	76.6	167.7	-62.7	-29.9	0	0	0	105.9	S483 E487	S483-D485 PolarHBondContact O-N 2.76Å; S483-D485 PolarHBondContact OG-OD1 3.28Å; D485-E487 PolarHBondContact O-N 3.37Å
486	Y	36.8	Very low	39	Very low	185 Å²	185	133.8 Å²	133.8	73%	0.725	69%	0.694	S	S	*	*			trans	-78.2	96.2	170.8	-170.4	-93.2	0	0	0	106.2	E484 P488	E484-Y486 PolarHBondContact O-N 3.07Å; Y486-P488 WeakPolarHBondContact O-CD 3.47Å
487	E	36.9	Very low	39.2	Very low	172 Å²	172	134.3 Å²	134.3	80%	0.804	70%	0.697	S	S	*	*			trans	-67.4	122.6	161	-79	-163.5	167.8	0	0	107.6	D485 V489	D485-E487 PolarHBondContact O-N 3.37Å; E487-V489 PolarHBondContact O-N 3.12Å; E487-V489 VanDerWaalsContact O-N 3.12Å
488	P	30.9	Very low	39.7	Very low	108 Å²	108	136.5 Å²	136.5	70%	0.701	70%	0.704	S	S	*	*			trans	-66.4	114.1	179.4	26.4	-31.5	0	0	0	108.8	Y486 E490	Y486-P488 WeakPolarHBondContact O-CD 3.47Å; P488-E490 PolarHBondContact O-N 3.31Å
489	V	40.5	Very low	40	Very low	127 Å²	127	137.8 Å²	137.8	77%	0.77	70%	0.704	S	S	*	*			trans	-68.5	127	161.8	-177	0	0	0	0	106.5	E487	E487-V489 PolarHBondContact O-N 3.12Å; E487-V489 VanDerWaalsContact O-N 3.12Å
490	E	38.5	Very low	40	Very low	181 Å²	181	144.8 Å²	144.8	85%	0.846	73%	0.733	S	S	*	*			trans	-41.7	135.8	-175.8	-65.3	173.1	154.6	0	0	112.9	P488 D492	P488-E490 PolarHBondContact O-N 3.31Å; E490-D492 PolarHBondContact O-N 3.04Å
491	E	38.2	Very low	39.8	Very low	183 Å²	183	147.2 Å²	147.2	86%	0.855	74%	0.74	S	S	*	*			trans	-63.9	94.3	179.7	-63.5	170.3	155.8	0	0	110.7
492	D	43.9	Very low	40.1	Very low	148 Å²	148	152 Å²	152	79%	0.791	77%	0.773	S	S	*	*			trans	-134.8	68.4	151	-80.5	-35.5	0	0	0	105.4	E490	E490-D492 PolarHBondContact O-N 3.04Å
493	E	38.5	Very low	40.1	Very low	149 Å²	149	156.3 Å²	156.3	70%	0.696	79%	0.794	S	S	*	*				71.7	131.3	80	-140.1	-150.2	170.8	0	0	110.9
494	W	55.3	Low	40.2	Very low	207 Å²	207	160.4 Å²	160.4	78%	0.784	81%	0.807	S	S	*	*			trans	89.7	-15.9	161.7	1.4	-39.3	0	0	0	124.1
495	L	43.1	Very low	40.2	Very low	158 Å²	158	160.1 Å²	160.1	83%	0.827	81%	0.809	S	S	*	*	S	Bend	trans	-100.2	4.1	-169.3	-98.6	167.1	0	0	0	119.4
496	L	41.8	Very low	40.5	Very low	153 Å²	153	162.2 Å²	162.2	80%	0.801	82%	0.818	S	S	*	*	S	Bend	trans	-113.9	-15.3	-177	-69.8	175.6	0	0	0	118.2	L498	L496-L498 VanDerWaalsContact C-N 3.28Å; L496-L498 PolarHBondContact O-N 3.45Å
497	P	41.5	Very low	40.7	Very low	114 Å²	114	160.8 Å²	160.8	74%	0.74	82%	0.824	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.6	3.2	173.3	-21.5	35.2	0	0	0	116.6
498	L	44.8	Very low	41	Very low	163 Å²	163	160 Å²	160	85%	0.853	83%	0.825	S	S	*	*	T	Hydrogen-bonded Turn	trans	-91.8	3.7	177.4	-80.3	179.1	0	0	0	115.5	L496	L496-L498 VanDerWaalsContact C-N 3.28Å; L496-L498 PolarHBondContact O-N 3.45Å
499	L	39.4	Very low	41.7	Very low	136 Å²	136	163.7 Å²	163.7	71%	0.712	83%	0.834	S	S	*	*	S	Bend	trans	-107.3	-3.6	-177.8	-117.8	96.4	0	0	0	116.6
500	F	36.4	Very low	41.8	Very low	186 Å²	186	166.5 Å²	166.5	82%	0.816	84%	0.839	S	S	*	*			trans	-146.6	68.5	-178.1	-58.8	-75.6	0	0	0	112.6
501	E	35.3	Very low	42	Very low	183 Å²	183	165.3 Å²	165.3	86%	0.855	84%	0.838	S	S	*	*			trans	-110.6	142.8	145.9	-90.9	-172.2	163.3	0	0	108
502	P	46.4	Very low	42.4	Very low	204 Å²	204	163.7 Å²	163.7	100%	1.325	84%	0.836	S	S	*	*			trans	-67	0	-155.4	26.1	-35.9	0	0	0	116.3

Retrieved 502 of 502 residues in 719.4 ms (Link to these results)

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