G4VPT0_SCHMA Loading...

Putative vesicular acetylcholine transporter

AlphaFold DB , UniProt , Accession G4VPT0, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 539 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	54.3	Low	82.8	Confident	211 Å²	211	118.4 Å²	118.4	100%	1.039	59%	0.588	S	S	*	*				0	-30.2	0	-82.2	170.9	168.6	0	0	113	N3 F4	M1-N3 PolarHBondContact O-N 2.98Å; M1-F4 PolarHBondContact O-N 3.36Å
2	T	75.1	Confident	83.2	Confident	106 Å²	106	113 Å²	113	65%	0.65	56%	0.561	S	S	*	*	H	α-helix	trans	-53.7	-45.2	-179.9	45.3	0	0	0	0	115.3	F4 E5 T6	T2-F4 PolarHBondContact O-N 2.67Å; T2-E5 PolarHBondContact O-N 3.04Å; T2-T6 PolarHBondContact O-N 3.06Å; T2-T6 VanDerWaalsContact O-N 3.09Å; T2-T6 PolarHBondContact O-OG1 3.13Å
3	N	85.1	Confident	83.6	Confident	124 Å²	124	109.7 Å²	109.7	66%	0.663	56%	0.556	S	S	*	*	H	α-helix	trans	-62.3	-37.3	-176.5	-80.5	-4.9	0	0	0	114.2	M1 I7	M1-N3 PolarHBondContact O-N 2.98Å; N3-I7 WeakPolarHBondContact O-CB 3.25Å; N3-I7 WeakPolarHBondContact O-CD1 3.31Å; N3-I7 WeakPolarHBondContact O-CG1 3.41Å; N3-I7 PolarHBondContact O-N 3.1Å
4	F	85.1	Confident	83.9	Confident	153 Å²	153	109.5 Å²	109.5	67%	0.671	55%	0.549	S	S	*	.	H	α-helix	trans	-71.6	-41.3	-177.3	-177.3	-99.8	0	0	0	111.7	M1 T2 I7 K8	M1-F4 PolarHBondContact O-N 3.36Å; T2-F4 PolarHBondContact O-N 2.67Å; F4-I7 PolarHBondContact O-N 3.07Å; F4-K8 VanDerWaalsContact O-CB 3.31Å; F4-K8 WeakPolarHBondContact O-CB 3.48Å; F4-K8 PolarHBondContact O-N 3.07Å
5	E	86.4	Confident	84.3	Confident	120 Å²	120	102.3 Å²	102.3	56%	0.561	51%	0.513	S	S	*	.	H	α-helix	trans	-65.4	-42.1	176.5	-69	-177.5	161.7	0	0	111.4	T2 I7 K8 Q9	T2-E5 PolarHBondContact O-N 3.04Å; E5-I7 PolarHBondContact O-N 3.22Å; E5-K8 PolarHBondContact O-N 3.21Å; E5-Q9 WeakPolarHBondContact O-CB 3.45Å; E5-Q9 WeakPolarHBondContact O-CG 3.33Å; E5-Q9 PolarHBondContact O-N 3.48Å
6	T	87.6	Confident	84.5	Confident	69 Å²	69	102.9 Å²	102.9	42%	0.423	52%	0.518	S	S	.	.	H	α-helix	trans	-60.9	-45.8	174.5	-52.3	0	0	0	0	111.5	T2 K8 Q9 I10	T2-T6 PolarHBondContact O-N 3.06Å; T2-T6 VanDerWaalsContact O-N 3.09Å; T2-T6 PolarHBondContact O-OG1 3.13Å; T6-K8 VanDerWaalsContact C-N 3.34Å; T6-K8 PolarHBondContact O-N 3.03Å; T6-Q9 PolarHBondContact O-N 2.75Å; T6-I10 HydrophobicContact CG2-CD1 3.95Å; T6-I10 VanDerWaalsContact O-CG1 3.28Å; T6-I10 WeakPolarHBondContact O-CG1 3.35Å; T6-I10 PolarHBondContact O-N 3Å
7	I	86.1	Confident	84.9	Confident	111 Å²	111	102.7 Å²	102.7	57%	0.569	52%	0.515	S	S	*	.	H	α-helix	trans	-61.8	-44	176.8	-70.3	164.7	0	0	0	110.5	N3 F4 E5 Q9 I10 F11	N3-I7 WeakPolarHBondContact O-CB 3.25Å; N3-I7 WeakPolarHBondContact O-CD1 3.31Å; N3-I7 WeakPolarHBondContact O-CG1 3.41Å; N3-I7 PolarHBondContact O-N 3.1Å; F4-I7 PolarHBondContact O-N 3.07Å; E5-I7 PolarHBondContact O-N 3.22Å; I7-Q9 PolarHBondContact O-N 3.05Å; I7-I10 PolarHBondContact O-N 2.92Å; I7-F11 VanDerWaalsContact O-CB 3.31Å; I7-F11 WeakPolarHBondContact O-CB 3.45Å; I7-F11 PolarHBondContact O-N 2.87Å
8	K	87.3	Confident	85.1	Confident	117 Å²	117	101.3 Å²	101.3	51%	0.509	51%	0.514	S	S	.	.	H	α-helix	trans	-60.7	-44.2	177.2	-176.8	-178.9	176.1	-174.3	0	111.2	F4 E5 T6 F11 M12	F4-K8 VanDerWaalsContact O-CB 3.31Å; F4-K8 WeakPolarHBondContact O-CB 3.48Å; F4-K8 PolarHBondContact O-N 3.07Å; E5-K8 PolarHBondContact O-N 3.21Å; T6-K8 VanDerWaalsContact C-N 3.34Å; T6-K8 PolarHBondContact O-N 3.03Å; K8-F11 PolarHBondContact O-N 3.36Å; K8-M12 HydrophobicContact CG-CG 4.42Å; K8-M12 WeakPolarHBondContact O-CB 3.29Å; K8-M12 WeakPolarHBondContact O-CG 3.46Å; K8-M12 PolarHBondContact O-N 3.27Å
9	Q	87.3	Confident	85.4	Confident	135 Å²	135	100.2 Å²	100.2	63%	0.631	51%	0.51	S	S	*	.	H	α-helix	trans	-64	-44.7	177.5	-74.8	175.9	-5.5	0	0	112.2	E5 T6 I7 F11 M12 S13	E5-Q9 WeakPolarHBondContact O-CB 3.45Å; E5-Q9 WeakPolarHBondContact O-CG 3.33Å; E5-Q9 PolarHBondContact O-N 3.48Å; T6-Q9 PolarHBondContact O-N 2.75Å; I7-Q9 PolarHBondContact O-N 3.05Å; Q9-F11 VanDerWaalsContact C-N 3.29Å; Q9-F11 PolarHBondContact O-N 2.61Å; Q9-M12 PolarHBondContact O-N 3.32Å; Q9-S13 WeakPolarHBondContact O-CB 3.36Å; Q9-S13 PolarHBondContact O-N 3.37Å; Q9-S13 PolarHBondContact O-OG 3.22Å
10	I	87.5	Confident	85.7	Confident	90 Å²	90	96.4 Å²	96.4	46%	0.462	49%	0.493	S	S	.	.	H	α-helix	trans	-62.4	-38.9	176	-67.4	166.3	0	0	0	111.1	T6 I7 S13 K14	T6-I10 HydrophobicContact CG2-CD1 3.95Å; T6-I10 VanDerWaalsContact O-CG1 3.28Å; T6-I10 WeakPolarHBondContact O-CG1 3.35Å; T6-I10 PolarHBondContact O-N 3Å; I7-I10 PolarHBondContact O-N 2.92Å; I10-S13 PolarHBondContact O-OG 3.49Å; I10-K14 WeakPolarHBondContact O-CG 3.41Å; I10-K14 PolarHBondContact O-N 2.94Å
11	F	88.7	Confident	86.2	Confident	66 Å²	66	92.3 Å²	92.3	29%	0.289	47%	0.472	S	S	.	.	H	α-helix	trans	-68.5	-43.9	177.9	-173.4	-108	0	0	0	111.5	I7 K8 Q9 K14 I15 M24 L234 I237 I238	I7-F11 VanDerWaalsContact O-CB 3.31Å; I7-F11 WeakPolarHBondContact O-CB 3.45Å; I7-F11 PolarHBondContact O-N 2.87Å; K8-F11 PolarHBondContact O-N 3.36Å; Q9-F11 VanDerWaalsContact C-N 3.29Å; Q9-F11 PolarHBondContact O-N 2.61Å; F11-K14 PolarHBondContact O-N 3.36Å; F11-I15 HydrophobicContact CD1-CD1 3.61Å; F11-I15 HydrophobicContact CE1-CD1 3.29Å; F11-I15 HydrophobicContact CE1-CG1 4.36Å; F11-I15 HydrophobicContact CG-CD1 4.41Å; F11-I15 HydrophobicContact CZ-CD1 3.85Å; F11-I15 WeakPolarHBondContact O-CG1 3.46Å; F11-I15 PolarHBondContact O-N 3.11Å; F11-M24 HydrophobicContact CD2-CE 4.08Å; F11-M24 HydrophobicContact CE2-CE 3.27Å; F11-M24 HydrophobicContact CZ-CE 3.6Å; F11-L234 HydrophobicContact CZ-CD1 3.93Å; F11-I237 HydrophobicContact CD1-CG2 4.48Å; F11-I237 HydrophobicContact CE1-CG2 3.75Å; F11-I238 HydrophobicContact CZ-CG1 4.49Å
12	M	88.1	Confident	88.1	Confident	54 Å²	54	84.2 Å²	84.2	27%	0.266	43%	0.43	S	S	.	.	H	α-helix	trans	-66.6	-38.4	177.3	-69.6	-63.3	171.3	0	0	112.4	K8 Q9 K14 I15 N16 I237	K8-M12 HydrophobicContact CG-CG 4.42Å; K8-M12 WeakPolarHBondContact O-CB 3.29Å; K8-M12 WeakPolarHBondContact O-CG 3.46Å; K8-M12 PolarHBondContact O-N 3.27Å; Q9-M12 PolarHBondContact O-N 3.32Å; M12-K14 VanDerWaalsContact C-N 3.31Å; M12-K14 PolarHBondContact O-N 2.99Å; M12-I15 PolarHBondContact O-N 3.44Å; M12-I15 HydrophobicContact SD-CD1 4.28Å; M12-N16 PolarHBondContact O-N 3.36Å; M12-N16 PolarHBondContact O-ND2 3.24Å; M12-I237 HydrophobicContact CE-CG2 3.88Å
13	S	87.5	Confident	89.1	Confident	70 Å²	70	87.5 Å²	87.5	49%	0.49	43%	0.43	S	S	.	.	H	α-helix	trans	-63.2	-39.1	175.3	67.6	0	0	0	0	111.8	Q9 I10 N16 E17	Q9-S13 WeakPolarHBondContact O-CB 3.36Å; Q9-S13 PolarHBondContact O-N 3.37Å; Q9-S13 PolarHBondContact O-OG 3.22Å; I10-S13 PolarHBondContact O-OG 3.49Å; S13-N16 PolarHBondContact O-N 2.8Å; S13-E17 PolarHBondContact O-N 3.14Å; S13-E17 VanDerWaalsContact O-N 3.14Å
14	K	88.9	Confident	89.6	Confident	107 Å²	107	83.2 Å²	83.2	47%	0.465	41%	0.407	S	S	.	.	H	α-helix	trans	-65.1	-35.7	172.6	-77.7	-175.5	177.7	-175.8	0	113.5	I10 F11 M12 N16 E17 S20 M24	I10-K14 WeakPolarHBondContact O-CG 3.41Å; I10-K14 PolarHBondContact O-N 2.94Å; F11-K14 PolarHBondContact O-N 3.36Å; M12-K14 VanDerWaalsContact C-N 3.31Å; M12-K14 PolarHBondContact O-N 2.99Å; K14-N16 VanDerWaalsContact C-N 3.31Å; K14-E17 PolarHBondContact O-N 3.47Å; K14-S20 VanDerWaalsContact O-CB 3.24Å; K14-S20 WeakPolarHBondContact O-CB 3.17Å; K14-S20 PolarHBondContact O-OG 2.86Å; K14-M24 HydrophobicContact CB-SD 4.47Å
15	I	89.3	Confident	90.1	Very high	1 Å²	1	76 Å²	76	1%	0.005	38%	0.375	C	S	.	.	H	α-helix	trans	-68.2	-33.9	176.1	-75	169.6	0	0	0	111.4	F11 M12 Q21 M24 I237 I238 P241	F11-I15 HydrophobicContact CD1-CD1 3.61Å; F11-I15 HydrophobicContact CE1-CD1 3.29Å; F11-I15 HydrophobicContact CE1-CG1 4.36Å; F11-I15 HydrophobicContact CG-CD1 4.41Å; F11-I15 HydrophobicContact CZ-CD1 3.85Å; F11-I15 WeakPolarHBondContact O-CG1 3.46Å; F11-I15 PolarHBondContact O-N 3.11Å; M12-I15 PolarHBondContact O-N 3.44Å; M12-I15 HydrophobicContact SD-CD1 4.28Å; I15-Q21 WeakPolarHBondContact O-CB 3.31Å; I15-Q21 PolarHBondContact O-NE2 3.31Å; I15-M24 HydrophobicContact CG1-CE 4.04Å; I15-M24 HydrophobicContact CG1-SD 4.19Å; I15-I237 HydrophobicContact CD1-CG2 3.85Å; I15-I238 HydrophobicContact CD1-CG1 4.3Å; I15-I238 HydrophobicContact CG1-CG1 4.39Å; I15-P241 HydrophobicContact CG2-CG 3.4Å; I15-P241 VanDerWaalsContact CG2-CG 3.4Å
16	N	87.9	Confident	90.6	Very high	112 Å²	112	71.1 Å²	71.1	60%	0.599	35%	0.353	S	S	*	.	H	α-helix	trans	-76.6	-22.8	177.9	-68.4	-21.2	0	0	0	112.8	M12 S13 K14 P18	M12-N16 PolarHBondContact O-N 3.36Å; M12-N16 PolarHBondContact O-ND2 3.24Å; S13-N16 PolarHBondContact O-N 2.8Å; K14-N16 VanDerWaalsContact C-N 3.31Å; N16-P18 WeakPolarHBondContact O-CD 3.37Å
17	E	91	Very high	91.1	Very high	100 Å²	100	73.2 Å²	73.2	47%	0.467	36%	0.356	S	S	.	.	S	Bend	trans	-76.3	117.2	174.8	-170.9	-167.3	165.6	0	0	111	S13 K14 N19 S20 Q21	S13-E17 PolarHBondContact O-N 3.14Å; S13-E17 VanDerWaalsContact O-N 3.14Å; K14-E17 PolarHBondContact O-N 3.47Å; E17-N19 VanDerWaalsContact C-N 3.32Å; E17-N19 PolarHBondContact O-N 2.64Å; E17-S20 PolarHBondContact O-N 2.87Å; E17-S20 VanDerWaalsContact O-N 3.12Å; E17-Q21 WeakPolarHBondContact O-CB 3.05Å; E17-Q21 PolarHBondContact O-N 2.95Å
18	P	88.9	Confident	91.6	Very high	77 Å²	77	67.9 Å²	67.9	50%	0.5	33%	0.329	S	S	.	.	H	α-helix	trans	-57.7	-39.4	-172.2	-27.1	34.7	0	0	0	114.5	N16 R22	N16-P18 WeakPolarHBondContact O-CD 3.37Å; P18-R22 WeakPolarHBondContact O-CG 3.45Å; P18-R22 PolarHBondContact O-N 2.86Å; P18-R22 VanDerWaalsContact O-N 3.1Å
19	N	90.4	Very high	92.1	Very high	81 Å²	81	62.3 Å²	62.3	43%	0.433	31%	0.305	S	S	.	.	H	α-helix	trans	-69.2	-36.1	-179.5	-82.4	-44	0	0	0	113.2	E17 R22 R23	E17-N19 VanDerWaalsContact C-N 3.32Å; E17-N19 PolarHBondContact O-N 2.64Å; N19-R22 WeakPolarHBondContact O-CG 3.44Å; N19-R22 VanDerWaalsContact OD1-CZ 3.25Å; N19-R22 PolarHBondContact OD1-NE 3.05Å; N19-R22 VanDerWaalsContact OD1-NE 3.11Å; N19-R22 PolarHBondContact OD1-NH2 3.17Å; N19-R23 WeakPolarHBondContact O-CG 3.29Å
20	S	92.5	Very high	92.6	Very high	23 Å²	23	56 Å²	56	16%	0.161	28%	0.275	C	S	.	.	H	α-helix	trans	-76.1	-45.3	178	-177.6	0	0	0	0	109.8	K14 E17 R22 R23 M24	K14-S20 VanDerWaalsContact O-CB 3.24Å; K14-S20 WeakPolarHBondContact O-CB 3.17Å; K14-S20 PolarHBondContact O-OG 2.86Å; E17-S20 PolarHBondContact O-N 2.87Å; E17-S20 VanDerWaalsContact O-N 3.12Å; S20-R22 PolarHBondContact O-N 3.49Å; S20-R23 WeakPolarHBondContact O-CB 3.33Å; S20-R23 PolarHBondContact O-N 3.14Å; S20-R23 VanDerWaalsContact O-N 3.17Å; S20-M24 WeakPolarHBondContact O-CG 3.26Å; S20-M24 PolarHBondContact O-N 3.24Å
21	Q	94.4	Very high	93.1	Very high	12 Å²	12	53.3 Å²	53.3	6%	0.056	26%	0.261	C	S	.	.	H	α-helix	trans	-53.4	-52.7	176.1	-172.6	-157.1	82.8	0	0	112.6	I15 E17 R23 M24 V25 I238	I15-Q21 WeakPolarHBondContact O-CB 3.31Å; I15-Q21 PolarHBondContact O-NE2 3.31Å; E17-Q21 WeakPolarHBondContact O-CB 3.05Å; E17-Q21 PolarHBondContact O-N 2.95Å; Q21-R23 PolarHBondContact O-N 2.84Å; Q21-M24 WeakPolarHBondContact O-CB 3.37Å; Q21-M24 PolarHBondContact O-N 3.11Å; Q21-V25 HydrophobicContact CG-CG2 4.44Å; Q21-V25 WeakPolarHBondContact O-CG2 3.39Å; Q21-V25 PolarHBondContact O-N 3.22Å; Q21-I238 HydrophobicContact CG-CG2 4.29Å
22	R	94.7	Very high	93.5	Very high	41 Å²	41	50.3 Å²	50.3	16%	0.155	25%	0.249	C	C	.	.	H	α-helix	trans	-59.8	-33.6	-178.2	66.5	-174.6	179.8	149.6	0.3	113.2	P18 N19 S20 L26 R179 Y180 E185	P18-R22 WeakPolarHBondContact O-CG 3.45Å; P18-R22 PolarHBondContact O-N 2.86Å; P18-R22 VanDerWaalsContact O-N 3.1Å; N19-R22 WeakPolarHBondContact O-CG 3.44Å; N19-R22 VanDerWaalsContact OD1-CZ 3.25Å; N19-R22 PolarHBondContact OD1-NE 3.05Å; N19-R22 VanDerWaalsContact OD1-NE 3.11Å; N19-R22 PolarHBondContact OD1-NH2 3.17Å; S20-R22 PolarHBondContact O-N 3.49Å; R22-L26 PolarHBondContact O-N 3.3Å; R22-R179 HydrophobicContact CB-CB 3.99Å; R22-Y180 HydrophobicContact CB-CE2 4.25Å; R22-Y180 HydrophobicContact CG-CE1 4.37Å; R22-Y180 PolarHBondContact O-OH 3.35Å; R22-E185 IonicContact CZ-OE2 3.68Å; R22-E185 IonicContact NH1-OE1 3.69Å; R22-E185 IonicContact NH1-OE2 2.68Å; R22-E185 PolarHBondContact NH1-OE2 3.05Å; R22-E185 IonicContact NH2-OE1 3.5Å; R22-E185 IonicContact NH2-OE2 3.84Å
23	R	96.1	Very high	93.8	Very high	174 Å²	174	47.9 Å²	47.9	66%	0.657	24%	0.237	S	C	*	.	H	α-helix	trans	-71	-37.9	174.6	-68.7	176.1	-178.6	179.6	2.6	112	N19 S20 Q21 L26 F27	N19-R23 WeakPolarHBondContact O-CG 3.29Å; S20-R23 WeakPolarHBondContact O-CB 3.33Å; S20-R23 PolarHBondContact O-N 3.14Å; S20-R23 VanDerWaalsContact O-N 3.17Å; Q21-R23 PolarHBondContact O-N 2.84Å; R23-L26 PolarHBondContact O-N 3.47Å; R23-F27 PolarHBondContact O-N 2.88Å
24	M	95.7	Very high	94.2	Very high	35 Å²	35	45.5 Å²	45.5	17%	0.172	22%	0.219	C	C	.	.	H	α-helix	trans	-67	-40.2	174.8	-65.1	174.4	76.2	0	0	111.4	F11 K14 I15 S20 Q21 F27 V28 I238	F11-M24 HydrophobicContact CD2-CE 4.08Å; F11-M24 HydrophobicContact CE2-CE 3.27Å; F11-M24 HydrophobicContact CZ-CE 3.6Å; K14-M24 HydrophobicContact CB-SD 4.47Å; I15-M24 HydrophobicContact CG1-CE 4.04Å; I15-M24 HydrophobicContact CG1-SD 4.19Å; S20-M24 WeakPolarHBondContact O-CG 3.26Å; S20-M24 PolarHBondContact O-N 3.24Å; Q21-M24 WeakPolarHBondContact O-CB 3.37Å; Q21-M24 PolarHBondContact O-N 3.11Å; M24-F27 WeakPolarHBondContact O-CB 3.38Å; M24-F27 PolarHBondContact O-N 3.46Å; M24-V28 WeakPolarHBondContact O-CG2 3.38Å; M24-V28 PolarHBondContact O-N 3.24Å; M24-I238 HydrophobicContact CB-CD1 3.93Å; M24-I238 HydrophobicContact CB-CG1 4.33Å; M24-I238 HydrophobicContact CB-CG2 4.04Å; M24-I238 HydrophobicContact CE-CD1 4.01Å; M24-I238 HydrophobicContact CE-CG1 3.83Å
25	V	95.9	Very high	94.5	Very high	0 Å²	0	40.6 Å²	40.6	0%	0	20%	0.197	C	C	.	.	H	α-helix	trans	-59.1	-50.3	171.8	167.7	0	0	0	0	110.8	Q21 F27 V28 V29 M175 R179 I238 M239	Q21-V25 HydrophobicContact CG-CG2 4.44Å; Q21-V25 WeakPolarHBondContact O-CG2 3.39Å; Q21-V25 PolarHBondContact O-N 3.22Å; V25-F27 VanDerWaalsContact C-N 3.27Å; V25-F27 PolarHBondContact O-N 3.45Å; V25-V28 PolarHBondContact O-N 3.11Å; V25-V29 HydrophobicContact CG1-CG2 4.37Å; V25-V29 WeakPolarHBondContact O-CG2 3.4Å; V25-V29 PolarHBondContact O-N 2.6Å; V25-M175 HydrophobicContact CG1-CB 4.45Å; V25-M175 HydrophobicContact CG1-CG 3.65Å; V25-M175 HydrophobicContact CG1-SD 3.49Å; V25-M175 WeakPolarHBondContact CG1-SD 3.46Å; V25-M175 HydrophobicContact CG2-SD 4.48Å; V25-R179 HydrophobicContact CG1-CG 4.24Å; V25-I238 HydrophobicContact CG2-CG2 3.72Å; V25-M239 HydrophobicContact CG2-SD 3.64Å
26	L	97.6	Very high	94.7	Very high	19 Å²	19	40.9 Å²	40.9	10%	0.099	20%	0.199	C	C	.	.	H	α-helix	trans	-55.3	-44.9	176	175.9	59.4	0	0	0	111.4	R22 R23 V29 C30 I176 Y180 A189 I192	R22-L26 PolarHBondContact O-N 3.3Å; R23-L26 PolarHBondContact O-N 3.47Å; L26-V29 PolarHBondContact O-N 3.19Å; L26-C30 WeakPolarHBondContact O-CB 3.32Å; L26-C30 PolarHBondContact O-N 3.41Å; L26-C30 PolarHBondContact O-SG 2.81Å; L26-I176 HydrophobicContact CD1-CD1 3.63Å; L26-I176 HydrophobicContact CD1-CG1 4.06Å; L26-Y180 HydrophobicContact CB-CE2 4.08Å; L26-Y180 HydrophobicContact CD2-CE2 4.47Å; L26-A189 HydrophobicContact CD1-CB 4.13Å; L26-A189 WeakPolarHBondContact CD1-O 3.4Å; L26-A189 HydrophobicContact CD2-CB 4.11Å; L26-I192 HydrophobicContact CD2-CD1 4.3Å
27	F	97.5	Very high	94.9	Very high	112 Å²	112	37 Å²	37	49%	0.491	18%	0.178	S	C	.	.	H	α-helix	trans	-59.6	-49.1	178.5	178.1	-100.6	0	0	0	112.4	R23 M24 V25 C30 I31	R23-F27 PolarHBondContact O-N 2.88Å; M24-F27 WeakPolarHBondContact O-CB 3.38Å; M24-F27 PolarHBondContact O-N 3.46Å; V25-F27 VanDerWaalsContact C-N 3.27Å; V25-F27 PolarHBondContact O-N 3.45Å; F27-C30 WeakPolarHBondContact O-CB 3.5Å; F27-C30 PolarHBondContact O-N 2.94Å; F27-I31 HydrophobicContact CD1-CG1 4.47Å; F27-I31 HydrophobicContact CE1-CG1 4.07Å; F27-I31 HydrophobicContact CE2-CD1 4.31Å; F27-I31 HydrophobicContact CE2-CG1 4.38Å; F27-I31 HydrophobicContact CZ-CD1 4.12Å; F27-I31 HydrophobicContact CZ-CG1 4.02Å; F27-I31 WeakPolarHBondContact O-CG1 3.33Å; F27-I31 PolarHBondContact O-N 3.14Å
28	V	97	Very high	95	Very high	0 Å²	0	33 Å²	33	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-59.6	-47.7	177.3	167.3	0	0	0	0	111.3	M24 V25 C30 I31 A32 M131 D231 L234 L235 I238	M24-V28 WeakPolarHBondContact O-CG2 3.38Å; M24-V28 PolarHBondContact O-N 3.24Å; V25-V28 PolarHBondContact O-N 3.11Å; V28-C30 VanDerWaalsContact C-N 3.3Å; V28-C30 PolarHBondContact O-N 2.94Å; V28-I31 PolarHBondContact O-N 3.26Å; V28-I31 VanDerWaalsContact O-N 3.08Å; V28-A32 PolarHBondContact O-N 2.68Å; V28-M131 HydrophobicContact CG1-CE 4.12Å; V28-D231 WeakPolarHBondContact CG1-OD1 3.4Å; V28-L234 HydrophobicContact CG2-CD2 3.91Å; V28-L234 HydrophobicContact CG2-CG 3.91Å; V28-L235 HydrophobicContact CG1-CB 3.75Å; V28-L235 HydrophobicContact CG1-CD1 3.69Å; V28-L235 HydrophobicContact CG1-CG 4.27Å; V28-I238 HydrophobicContact CG2-CD1 3.59Å
29	V	97.7	Very high	95.2	Very high	0 Å²	0	29.4 Å²	29.4	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-61.2	-40.2	177.6	174.7	0	0	0	0	111.7	V25 L26 I31 A32 L33 M131 M175 I176	V25-V29 HydrophobicContact CG1-CG2 4.37Å; V25-V29 WeakPolarHBondContact O-CG2 3.4Å; V25-V29 PolarHBondContact O-N 2.6Å; L26-V29 PolarHBondContact O-N 3.19Å; V29-I31 VanDerWaalsContact C-N 3.31Å; V29-I31 PolarHBondContact O-N 3.35Å; V29-A32 PolarHBondContact O-N 2.91Å; V29-L33 HydrophobicContact CG1-CD1 3.86Å; V29-L33 HydrophobicContact CG1-CG 4.28Å; V29-L33 WeakPolarHBondContact O-CG 3.41Å; V29-L33 PolarHBondContact O-N 3.11Å; V29-M131 HydrophobicContact CG2-CE 4.12Å; V29-M131 HydrophobicContact CG2-SD 4.31Å; V29-M175 HydrophobicContact CG2-SD 4.48Å; V29-I176 HydrophobicContact CB-CD1 4Å; V29-I176 HydrophobicContact CB-CG1 4.2Å; V29-I176 HydrophobicContact CG1-CD1 3.48Å; V29-I176 VanDerWaalsContact CG1-CD1 3.48Å; V29-I176 HydrophobicContact CG1-CG1 4.02Å; V29-I176 HydrophobicContact CG2-CG1 4.34Å
30	C	97.8	Very high	95	Very high	2 Å²	2	26.6 Å²	26.6	1%	0.014	12%	0.12	C	C	.	.	H	α-helix	trans	-61	-38.5	174.5	-75	0	0	0	0	112.5	L26 F27 V28 L34 F196	L26-C30 WeakPolarHBondContact O-CB 3.32Å; L26-C30 PolarHBondContact O-N 3.41Å; L26-C30 PolarHBondContact O-SG 2.81Å; F27-C30 WeakPolarHBondContact O-CB 3.5Å; F27-C30 PolarHBondContact O-N 2.94Å; V28-C30 VanDerWaalsContact C-N 3.3Å; V28-C30 PolarHBondContact O-N 2.94Å; C30-L34 WeakPolarHBondContact O-CB 3.32Å; C30-L34 PolarHBondContact O-N 2.95Å; C30-F196 HydrophobicContact CB-CB 4.08Å; C30-F196 HydrophobicContact CB-CD1 3.63Å; C30-F196 HydrophobicContact CB-CD2 3.97Å; C30-F196 HydrophobicContact CB-CE1 3.98Å; C30-F196 HydrophobicContact CB-CE2 4.29Å; C30-F196 HydrophobicContact CB-CG 3.62Å; C30-F196 HydrophobicContact CB-CZ 4.3Å
31	I	96.9	Very high	94.8	Very high	33 Å²	33	27 Å²	27	17%	0.169	12%	0.119	C	C	.	.	H	α-helix	trans	-67	-46.2	175	-64.4	-58.2	0	0	0	110.6	F27 V28 V29 L33 L34 L35 F196 I227 D231	F27-I31 HydrophobicContact CD1-CG1 4.47Å; F27-I31 HydrophobicContact CE1-CG1 4.07Å; F27-I31 HydrophobicContact CE2-CD1 4.31Å; F27-I31 HydrophobicContact CE2-CG1 4.38Å; F27-I31 HydrophobicContact CZ-CD1 4.12Å; F27-I31 HydrophobicContact CZ-CG1 4.02Å; F27-I31 WeakPolarHBondContact O-CG1 3.33Å; F27-I31 PolarHBondContact O-N 3.14Å; V28-I31 PolarHBondContact O-N 3.26Å; V28-I31 VanDerWaalsContact O-N 3.08Å; V29-I31 VanDerWaalsContact C-N 3.31Å; V29-I31 PolarHBondContact O-N 3.35Å; I31-L33 PolarHBondContact O-N 3.15Å; I31-L34 PolarHBondContact O-N 2.63Å; I31-L35 HydrophobicContact CG2-CD1 3.88Å; I31-L35 HydrophobicContact CG2-CG 4.25Å; I31-L35 WeakPolarHBondContact O-CB 3.38Å; I31-L35 WeakPolarHBondContact O-CG 3.46Å; I31-L35 PolarHBondContact O-N 3.21Å; I31-F196 HydrophobicContact CD1-CE1 4.5Å; I31-I227 HydrophobicContact CG2-CG2 4.2Å; I31-D231 HydrophobicContact CG2-CB 4.09Å
32	A	97	Very high	94.5	Very high	3 Å²	3	26.4 Å²	26.4	3%	0.025	12%	0.117	C	C	.	.	H	α-helix	trans	-56.1	-49.2	176.7	0	0	0	0	0	112.7	V28 V29 L34 L35 D36 M131 L135 D231	V28-A32 PolarHBondContact O-N 2.68Å; V29-A32 PolarHBondContact O-N 2.91Å; A32-L34 PolarHBondContact O-N 3.06Å; A32-L35 WeakPolarHBondContact O-CB 3.31Å; A32-L35 PolarHBondContact O-N 3.31Å; A32-D36 PolarHBondContact O-N 3.36Å; A32-M131 HydrophobicContact CB-CE 3.52Å; A32-L135 HydrophobicContact CB-CD2 4.2Å; A32-D231 WeakPolarHBondContact CB-OD2 3.31Å; A32-D231 PolarHBondContact N-OD2 3.35Å
33	L	96.2	Very high	94.1	Very high	4 Å²	4	24.4 Å²	24.4	2%	0.021	11%	0.109	C	C	.	.	H	α-helix	trans	-68.3	-35.2	-179.6	-68	172.5	0	0	0	112.9	V29 I31 N37 D169 L173 A193 I197	V29-L33 HydrophobicContact CG1-CD1 3.86Å; V29-L33 HydrophobicContact CG1-CG 4.28Å; V29-L33 WeakPolarHBondContact O-CG 3.41Å; V29-L33 PolarHBondContact O-N 3.11Å; I31-L33 PolarHBondContact O-N 3.15Å; L33-N37 PolarHBondContact O-N 2.86Å; L33-N37 PolarHBondContact O-ND2 3.28Å; L33-D169 HydrophobicContact CD2-CB 3.83Å; L33-D169 WeakPolarHBondContact CD2-OD1 3.4Å; L33-L173 HydrophobicContact CD1-CD2 4.06Å; L33-A193 HydrophobicContact CD1-CB 3.74Å; L33-I197 HydrophobicContact CB-CD1 4.2Å; L33-I197 HydrophobicContact CB-CG1 3.74Å; L33-I197 HydrophobicContact CD1-CD1 4.29Å; L33-I197 HydrophobicContact CD2-CD1 4.31Å
34	L	95.5	Very high	93.3	Very high	20 Å²	20	19.3 Å²	19.3	11%	0.105	10%	0.097	C	C	.	.	H	α-helix	trans	-61.9	-45.4	171	175.5	158.4	0	0	0	110.4	C30 I31 A32 N37 M38 F196 F199	C30-L34 WeakPolarHBondContact O-CB 3.32Å; C30-L34 PolarHBondContact O-N 2.95Å; I31-L34 PolarHBondContact O-N 2.63Å; A32-L34 PolarHBondContact O-N 3.06Å; L34-N37 PolarHBondContact O-N 3.34Å; L34-M38 HydrophobicContact CD2-CG 3.88Å; L34-M38 HydrophobicContact CD2-SD 3.47Å; L34-M38 WeakPolarHBondContact CD2-SD 3.47Å; L34-M38 HydrophobicContact CG-CG 4.47Å; L34-M38 HydrophobicContact CG-SD 4.49Å; L34-M38 WeakPolarHBondContact O-CB 3.35Å; L34-M38 VanDerWaalsContact O-CG 3.29Å; L34-M38 WeakPolarHBondContact O-CG 3.18Å; L34-M38 PolarHBondContact O-N 3.4Å; L34-F196 HydrophobicContact CB-CB 4.38Å; L34-F196 HydrophobicContact CB-CD1 4.28Å; L34-F196 HydrophobicContact CD1-CD1 3.72Å; L34-F196 HydrophobicContact CD1-CE1 4.33Å; L34-F199 HydrophobicContact CD1-CD1 3.68Å; L34-F199 HydrophobicContact CD1-CE1 4.25Å
35	L	94.9	Very high	92.4	Very high	3 Å²	3	19.7 Å²	19.7	2%	0.016	10%	0.102	C	C	.	.	H	α-helix	trans	-63.5	-42.8	179.7	-72.8	168	0	0	0	112.3	I31 A32 N37 M38 L39 L224 I227 A228	I31-L35 HydrophobicContact CG2-CD1 3.88Å; I31-L35 HydrophobicContact CG2-CG 4.25Å; I31-L35 WeakPolarHBondContact O-CB 3.38Å; I31-L35 WeakPolarHBondContact O-CG 3.46Å; I31-L35 PolarHBondContact O-N 3.21Å; A32-L35 WeakPolarHBondContact O-CB 3.31Å; A32-L35 PolarHBondContact O-N 3.31Å; L35-N37 VanDerWaalsContact C-N 3.34Å; L35-N37 PolarHBondContact O-N 3.33Å; L35-M38 PolarHBondContact O-N 3.46Å; L35-L39 WeakPolarHBondContact O-CB 3.15Å; L35-L39 WeakPolarHBondContact O-CG 3.41Å; L35-L39 PolarHBondContact O-N 3.42Å; L35-L224 HydrophobicContact CD2-CD2 3.79Å; L35-I227 HydrophobicContact CD1-CB 4.3Å; L35-I227 HydrophobicContact CD1-CG2 3.87Å; L35-I227 HydrophobicContact CD2-CB 3.81Å; L35-I227 HydrophobicContact CD2-CD1 4.4Å; L35-I227 HydrophobicContact CD2-CG2 3.75Å; L35-I227 HydrophobicContact CG-CG2 4.24Å; L35-A228 HydrophobicContact CD1-CB 4.04Å
36	D	93.9	Very high	91.7	Very high	7 Å²	7	19.8 Å²	19.8	4%	0.037	10%	0.103	C	C	.	.	H	α-helix	trans	-60.7	-45.4	178	-168.4	53.9	0	0	0	111.3	A32 M38 L39 Y40 K107 S165	A32-D36 PolarHBondContact O-N 3.36Å; D36-M38 PolarHBondContact O-N 2.91Å; D36-L39 PolarHBondContact O-N 3.46Å; D36-Y40 PolarHBondContact O-N 3.25Å; D36-K107 IonicContact OD1-NZ 3.48Å; D36-K107 PolarHBondContact OD1-NZ 3.45Å; D36-K107 IonicContact OD2-NZ 2.76Å; D36-K107 PolarHBondContact OD2-NZ 3.3Å; D36-S165 VanDerWaalsContact CG-OG 3.27Å; D36-S165 WeakPolarHBondContact OD1-CB 3.49Å; D36-S165 PolarHBondContact OD1-OG 3.02Å; D36-S165 PolarHBondContact OD2-OG 3.26Å
37	N	91	Very high	90.8	Very high	31 Å²	31	18.9 Å²	18.9	17%	0.166	10%	0.098	C	C	.	.	H	α-helix	trans	-69.4	-33.3	176.5	-81.4	-84.2	0	0	0	113	L33 L34 L35 Y40 M41 I197	L33-N37 PolarHBondContact O-N 2.86Å; L33-N37 PolarHBondContact O-ND2 3.28Å; L34-N37 PolarHBondContact O-N 3.34Å; L35-N37 VanDerWaalsContact C-N 3.34Å; L35-N37 PolarHBondContact O-N 3.33Å; N37-Y40 PolarHBondContact O-N 2.85Å; N37-M41 PolarHBondContact O-N 3.36Å; N37-I197 HydrophobicContact CB-CG2 4.44Å; N37-I197 VanDerWaalsContact CG-CG2 3.48Å; N37-I197 WeakPolarHBondContact ND2-CG1 3.29Å; N37-I197 VanDerWaalsContact ND2-CG2 3.29Å; N37-I197 WeakPolarHBondContact ND2-CG2 3.37Å
38	M	92.8	Very high	89.5	Confident	15 Å²	15	15 Å²	15	7%	0.074	8%	0.084	C	C	.	.	H	α-helix	trans	-63.4	-45	171.5	-77.1	-164.9	75.6	0	0	111.3	L34 L35 D36 Y40 M41 V42 V203 A204 F207 L224	L34-M38 HydrophobicContact CD2-CG 3.88Å; L34-M38 HydrophobicContact CD2-SD 3.47Å; L34-M38 WeakPolarHBondContact CD2-SD 3.47Å; L34-M38 HydrophobicContact CG-CG 4.47Å; L34-M38 HydrophobicContact CG-SD 4.49Å; L34-M38 WeakPolarHBondContact O-CB 3.35Å; L34-M38 VanDerWaalsContact O-CG 3.29Å; L34-M38 WeakPolarHBondContact O-CG 3.18Å; L34-M38 PolarHBondContact O-N 3.4Å; L35-M38 PolarHBondContact O-N 3.46Å; D36-M38 PolarHBondContact O-N 2.91Å; M38-Y40 VanDerWaalsContact C-N 3.28Å; M38-Y40 PolarHBondContact O-N 3.39Å; M38-M41 PolarHBondContact O-N 2.94Å; M38-V42 WeakPolarHBondContact O-CB 3.36Å; M38-V42 VanDerWaalsContact O-CG1 3.26Å; M38-V42 WeakPolarHBondContact O-CG1 3.49Å; M38-V42 PolarHBondContact O-N 3.02Å; M38-V203 HydrophobicContact CE-CG1 4.16Å; M38-A204 HydrophobicContact CB-CB 4.2Å; M38-A204 HydrophobicContact CE-CB 4.4Å; M38-A204 HydrophobicContact CG-CB 4.13Å; M38-F207 HydrophobicContact CE-CB 4.06Å; M38-F207 HydrophobicContact CE-CD1 3.54Å; M38-F207 HydrophobicContact CE-CE1 4.13Å; M38-F207 HydrophobicContact CE-CG 3.81Å; M38-L224 HydrophobicContact CB-CD1 4.32Å; M38-L224 HydrophobicContact CB-CD2 4.05Å; M38-L224 HydrophobicContact CE-CD2 3.97Å; M38-L224 HydrophobicContact SD-CD2 3.94Å
39	L	92.9	Very high	88.3	Confident	2 Å²	2	17.8 Å²	17.8	1%	0.01	10%	0.099	C	C	.	.	H	α-helix	trans	-63.3	-35.2	177.3	-74.1	168.8	0	0	0	112.5	L35 D36 I43 I138 T142 F221 L224	L35-L39 WeakPolarHBondContact O-CB 3.15Å; L35-L39 WeakPolarHBondContact O-CG 3.41Å; L35-L39 PolarHBondContact O-N 3.42Å; D36-L39 PolarHBondContact O-N 3.46Å; L39-I43 WeakPolarHBondContact O-CG2 2.96Å; L39-I138 HydrophobicContact CD1-CG2 3.37Å; L39-T142 HydrophobicContact CD2-CG2 3.5Å; L39-T142 VanDerWaalsContact CD2-CG2 3.5Å; L39-F221 HydrophobicContact CD2-CD1 4.28Å; L39-L224 HydrophobicContact CD2-CB 3.86Å; L39-L224 HydrophobicContact CD2-CD1 3.67Å; L39-L224 HydrophobicContact CD2-CG 4.41Å; L39-L224 HydrophobicContact CG-CB 4.4Å; L39-L224 HydrophobicContact CG-CD1 4.14Å
40	Y	87.8	Confident	87.2	Confident	22 Å²	22	19.4 Å²	19.4	9%	0.086	11%	0.105	C	C	.	.	H	α-helix	trans	-61.9	-57.5	170.9	-176.4	-101.1	0	0	0	110.6	D36 N37 M38 I43 F104 E288	D36-Y40 PolarHBondContact O-N 3.25Å; N37-Y40 PolarHBondContact O-N 2.85Å; M38-Y40 VanDerWaalsContact C-N 3.28Å; M38-Y40 PolarHBondContact O-N 3.39Å; Y40-I43 WeakPolarHBondContact O-CG1 3.21Å; Y40-F104 HydrophobicContact CD1-CE1 4.25Å; Y40-F104 AromaticContact CD2-CD1 3.58Å; Y40-F104 HydrophobicContact CD2-CD1 3.58Å; Y40-F104 AromaticContact CD2-CE1 3.77Å; Y40-F104 HydrophobicContact CD2-CE1 3.77Å; Y40-F104 HydrophobicContact CE1-CD1 4.38Å; Y40-F104 HydrophobicContact CE1-CE1 4.09Å; Y40-F104 HydrophobicContact CE2-CB 4.15Å; Y40-F104 AromaticContact CE2-CD1 3.15Å; Y40-F104 HydrophobicContact CE2-CD1 3.15Å; Y40-F104 AromaticContact CE2-CE1 3.61Å; Y40-F104 HydrophobicContact CE2-CE1 3.61Å; Y40-F104 AromaticContact CE2-CG 3.92Å; Y40-F104 HydrophobicContact CE2-CG 3.92Å; Y40-F104 HydrophobicContact CG-CD1 4.36Å; Y40-F104 HydrophobicContact CG-CE1 4.09Å; Y40-F104 AromaticContact CZ-CD1 3.61Å; Y40-F104 AromaticContact CZ-CE1 3.76Å; Y40-F104 VanDerWaalsContact O-CE1 3.28Å; Y40-F104 WeakPolarHBondContact O-CE1 3.3Å; Y40-E288 PolarHBondContact OH-OE2 2.84Å
41	M	87.8	Confident	86	Confident	31 Å²	31	19.7 Å²	19.7	15%	0.153	11%	0.107	C	C	.	.	H	α-helix	trans	-81.1	-23.9	-170.9	-71.3	-56.6	-178.4	0	0	115.5	N37 M38 I43 V44 A204 E288	N37-M41 PolarHBondContact O-N 3.36Å; M38-M41 PolarHBondContact O-N 2.94Å; M41-I43 PolarHBondContact O-N 3.4Å; M41-I43 VanDerWaalsContact O-N 3.09Å; M41-V44 WeakPolarHBondContact O-CB 3.42Å; M41-V44 WeakPolarHBondContact O-CG2 3.32Å; M41-V44 PolarHBondContact O-N 3.46Å; M41-V44 HydrophobicContact SD-CG2 4.44Å; M41-A204 HydrophobicContact CB-CB 3.62Å; M41-E288 WeakPolarHBondContact CE-OE1 3.36Å
42	V	88.8	Confident	84.6	Confident	0 Å²	0	20.4 Å²	20.4	0%	0	11%	0.109	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63.8	-20.3	-177.2	74.6	0	0	0	0	112.4	M38 P45 I46 A204 F207 P220 F221 L224	M38-V42 WeakPolarHBondContact O-CB 3.36Å; M38-V42 VanDerWaalsContact O-CG1 3.26Å; M38-V42 WeakPolarHBondContact O-CG1 3.49Å; M38-V42 PolarHBondContact O-N 3.02Å; V42-P45 WeakPolarHBondContact O-CD 3.18Å; V42-P45 WeakPolarHBondContact O-CG 3.22Å; V42-I46 HydrophobicContact CG2-CD1 4.16Å; V42-I46 WeakPolarHBondContact O-CD1 3.26Å; V42-I46 WeakPolarHBondContact O-CG1 3.05Å; V42-A204 HydrophobicContact CB-CB 4.41Å; V42-F207 HydrophobicContact CG2-CD1 4.02Å; V42-F207 HydrophobicContact CG2-CE1 4.35Å; V42-P220 HydrophobicContact CG2-CB 4.28Å; V42-F221 HydrophobicContact CG1-CD1 4.24Å; V42-F221 HydrophobicContact CG1-CE1 3.5Å; V42-F221 HydrophobicContact CG1-CZ 4.05Å; V42-L224 HydrophobicContact CB-CD1 4.38Å; V42-L224 HydrophobicContact CG1-CD1 4.01Å; V42-L224 HydrophobicContact CG2-CD1 4.43Å
43	I	85	Confident	83.3	Confident	0 Å²	0	23.8 Å²	23.8	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-81.1	-20.4	-175.7	69.6	105.3	0	0	0	112.8	L39 Y40 M41 I46 I47 I100 F104 F145 F221	L39-I43 WeakPolarHBondContact O-CG2 2.96Å; Y40-I43 WeakPolarHBondContact O-CG1 3.21Å; M41-I43 PolarHBondContact O-N 3.4Å; M41-I43 VanDerWaalsContact O-N 3.09Å; I43-I46 PolarHBondContact O-N 2.94Å; I43-I47 HydrophobicContact CB-CG1 3.96Å; I43-I47 WeakPolarHBondContact O-CB 3.23Å; I43-I47 WeakPolarHBondContact O-CG1 3.42Å; I43-I47 PolarHBondContact O-N 3.06Å; I43-I100 HydrophobicContact CD1-CG2 4Å; I43-F104 HydrophobicContact CD1-CD1 4.06Å; I43-F104 HydrophobicContact CD1-CD2 4.47Å; I43-F104 HydrophobicContact CD1-CE1 3.36Å; I43-F104 HydrophobicContact CD1-CE2 3.82Å; I43-F104 HydrophobicContact CD1-CZ 3.22Å; I43-F104 HydrophobicContact CG1-CE1 3.6Å; I43-F104 HydrophobicContact CG1-CZ 3.73Å; I43-F145 HydrophobicContact CG2-CE1 4.27Å; I43-F145 HydrophobicContact CG2-CZ 4.24Å; I43-F221 HydrophobicContact CG2-CE1 3.66Å; I43-F221 HydrophobicContact CG2-CZ 3.65Å
44	V	80.2	Confident	81.9	Confident	66 Å²	66	25.7 Å²	25.7	40%	0.4	14%	0.137	S	C	.	.	H	α-helix	trans	-57.3	-52	179.4	176.7	0	0	0	0	111.4	M41 P48 F104	M41-V44 WeakPolarHBondContact O-CB 3.42Å; M41-V44 WeakPolarHBondContact O-CG2 3.32Å; M41-V44 PolarHBondContact O-N 3.46Å; M41-V44 HydrophobicContact SD-CG2 4.44Å; V44-P48 WeakPolarHBondContact O-CD 3.49Å; V44-P48 WeakPolarHBondContact O-CG 3.35Å; V44-F104 HydrophobicContact CG2-CE2 4.31Å; V44-F104 HydrophobicContact CG2-CZ 3.66Å
45	P	76.8	Confident	80.3	Confident	44 Å²	44	27.7 Å²	27.7	29%	0.286	14%	0.143	S	C	.	.	H	α-helix	trans	-73.1	-26.1	177.3	26.9	-35.7	0	0	0	114.1	V42	V42-P45 WeakPolarHBondContact O-CD 3.18Å; V42-P45 WeakPolarHBondContact O-CG 3.22Å
46	I	79.8	Confident	78.5	Confident	1 Å²	1	29.9 Å²	29.9	1%	0.005	16%	0.162	C	C	.	.	H	α-helix	trans	-89.1	-49.2	-169.2	-59.9	176.8	0	0	0	112.5	V42 I43 D49 Y50 Y212 K217 P220 F221	V42-I46 HydrophobicContact CG2-CD1 4.16Å; V42-I46 WeakPolarHBondContact O-CD1 3.26Å; V42-I46 WeakPolarHBondContact O-CG1 3.05Å; I43-I46 PolarHBondContact O-N 2.94Å; I46-D49 PolarHBondContact O-N 2.87Å; I46-Y50 VanDerWaalsContact O-CB 3.31Å; I46-Y50 WeakPolarHBondContact O-CB 3.22Å; I46-Y50 PolarHBondContact O-N 2.9Å; I46-Y212 HydrophobicContact CG1-CD1 4.47Å; I46-Y212 HydrophobicContact CG1-CD2 4.32Å; I46-Y212 HydrophobicContact CG1-CG 3.98Å; I46-Y212 HydrophobicContact CG2-CD2 3.89Å; I46-Y212 HydrophobicContact CG2-CE2 4Å; I46-Y212 HydrophobicContact CG2-CG 4.31Å; I46-K217 HydrophobicContact CG2-CB 4.16Å; I46-P220 HydrophobicContact CD1-CB 4.04Å; I46-P220 HydrophobicContact CD1-CG 3.94Å; I46-F221 HydrophobicContact CD1-CE2 3.84Å; I46-F221 HydrophobicContact CD1-CZ 4.02Å; I46-F221 HydrophobicContact CG2-CE2 4.27Å
47	I	79	Confident	76.6	Confident	1 Å²	1	35.8 Å²	35.8	1%	0.005	19%	0.191	C	C	.	.	H	α-helix	trans	-69.4	-41.7	-167.3	-65.8	-67.2	0	0	0	114.8	I43 D49 Y50 L51 I100 L103 F145 M154	I43-I47 HydrophobicContact CB-CG1 3.96Å; I43-I47 WeakPolarHBondContact O-CB 3.23Å; I43-I47 WeakPolarHBondContact O-CG1 3.42Å; I43-I47 PolarHBondContact O-N 3.06Å; I47-D49 VanDerWaalsContact C-N 3.29Å; I47-D49 PolarHBondContact O-N 3.17Å; I47-Y50 PolarHBondContact O-N 3.4Å; I47-L51 HydrophobicContact CG2-CD1 3.56Å; I47-L51 HydrophobicContact CG2-CG 3.89Å; I47-L51 WeakPolarHBondContact O-CB 3.33Å; I47-L51 WeakPolarHBondContact O-CG 3.4Å; I47-L51 PolarHBondContact O-N 3.03Å; I47-I100 HydrophobicContact CB-CG1 4.29Å; I47-I100 HydrophobicContact CG2-CD1 4.46Å; I47-I100 HydrophobicContact CG2-CG1 3.71Å; I47-L103 HydrophobicContact CG2-CD1 4.08Å; I47-F145 HydrophobicContact CD1-CE1 3.7Å; I47-F145 HydrophobicContact CD1-CZ 3.46Å; I47-F145 VanDerWaalsContact CD1-CZ 3.46Å; I47-F145 HydrophobicContact CG1-CE1 4.4Å; I47-F145 HydrophobicContact CG1-CZ 4.05Å; I47-M154 HydrophobicContact CD1-CE 4.34Å; I47-M154 HydrophobicContact CD1-SD 3.85Å
48	P	71.8	Confident	74.8	Confident	31 Å²	31	39.5 Å²	39.5	20%	0.201	21%	0.211	C	C	.	.	H	α-helix	trans	-57.2	-45.9	176.3	-8.1	11	0	0	0	111.6	V44 Q52 I100	V44-P48 WeakPolarHBondContact O-CD 3.49Å; V44-P48 WeakPolarHBondContact O-CG 3.35Å; P48-Q52 WeakPolarHBondContact O-CB 3.43Å; P48-Q52 WeakPolarHBondContact O-CG 3.47Å; P48-Q52 PolarHBondContact O-N 3.34Å; P48-Q52 VanDerWaalsContact O-N 3.11Å; P48-Q52 PolarHBondContact O-NE2 2.88Å; P48-I100 HydrophobicContact CB-CD1 3.91Å; P48-I100 HydrophobicContact CG-CD1 3.46Å; P48-I100 VanDerWaalsContact CG-CD1 3.46Å
49	D	71.6	Confident	72.7	Confident	58 Å²	58	41.2 Å²	41.2	31%	0.31	22%	0.222	S	C	.	.	H	α-helix	trans	-67.2	-45.2	179.4	-171.5	68	0	0	0	111.5	I46 I47 L51 Q52 N53 Y212	I46-D49 PolarHBondContact O-N 2.87Å; I47-D49 VanDerWaalsContact C-N 3.29Å; I47-D49 PolarHBondContact O-N 3.17Å; D49-L51 PolarHBondContact O-N 3.21Å; D49-Q52 WeakPolarHBondContact O-CB 3.5Å; D49-Q52 PolarHBondContact O-N 2.92Å; D49-N53 PolarHBondContact O-N 3.43Å; D49-N53 PolarHBondContact O-ND2 2.85Å; D49-N53 PolarHBondContact OD2-ND2 3.25Å; D49-Y212 HydrophobicContact CB-CE1 4.14Å; D49-Y212 VanDerWaalsContact OD2-CE1 3.29Å; D49-Y212 WeakPolarHBondContact OD2-CE1 3.43Å; D49-Y212 PolarHBondContact OD2-OH 3.13Å
50	Y	74.4	Confident	70	Confident	33 Å²	33	51.1 Å²	51.1	13%	0.129	26%	0.26	C	S	.	.	H	α-helix	trans	-63.1	-43.9	179.2	-175	-101.2	0	0	0	113.3	I46 I47 Q52 N53 L54 G148 M154 K217	I46-Y50 VanDerWaalsContact O-CB 3.31Å; I46-Y50 WeakPolarHBondContact O-CB 3.22Å; I46-Y50 PolarHBondContact O-N 2.9Å; I47-Y50 PolarHBondContact O-N 3.4Å; Y50-Q52 VanDerWaalsContact C-N 3.3Å; Y50-Q52 PolarHBondContact O-N 3.39Å; Y50-N53 PolarHBondContact O-N 3.35Å; Y50-L54 HydrophobicContact CD1-CD1 3.87Å; Y50-L54 HydrophobicContact CD1-CG 4.27Å; Y50-L54 HydrophobicContact CE1-CD1 3.28Å; Y50-L54 HydrophobicContact CE1-CD2 4.38Å; Y50-L54 HydrophobicContact CE1-CG 3.78Å; Y50-L54 PolarHBondContact O-N 3.22Å; Y50-G148 PolarHBondContact OH-O 2.77Å; Y50-M154 HydrophobicContact CD1-CE 3.56Å; Y50-M154 HydrophobicContact CD1-SD 4.35Å; Y50-M154 HydrophobicContact CE1-CE 3.2Å; Y50-M154 HydrophobicContact CE1-SD 4.29Å; Y50-K217 HydrophobicContact CD2-CD 3.85Å; Y50-K217 HydrophobicContact CD2-CG 4.4Å; Y50-K217 HydrophobicContact CE1-CD 4.27Å; Y50-K217 HydrophobicContact CE2-CD 3.45Å; Y50-K217 VanDerWaalsContact CE2-CD 3.45Å; Y50-K217 HydrophobicContact CE2-CG 4.19Å; Y50-K217 HydrophobicContact CG-CD 4.41Å; Y50-K217 WeakPolarHBondContact OH-CE 3.4Å
51	L	72.1	Confident	67.4	Low	8 Å²	8	57.2 Å²	57.2	4%	0.042	29%	0.289	C	S	.	.	H	α-helix	trans	-67.4	-31.6	176.9	-70.1	178.5	0	0	0	112.3	I47 D49 L54 R55 K99 Y151	I47-L51 HydrophobicContact CG2-CD1 3.56Å; I47-L51 HydrophobicContact CG2-CG 3.89Å; I47-L51 WeakPolarHBondContact O-CB 3.33Å; I47-L51 WeakPolarHBondContact O-CG 3.4Å; I47-L51 PolarHBondContact O-N 3.03Å; D49-L51 PolarHBondContact O-N 3.21Å; L51-L54 HydrophobicContact CD2-CD1 4.44Å; L51-R55 WeakPolarHBondContact O-CG 3.17Å; L51-R55 PolarHBondContact O-N 3.49Å; L51-R55 VanDerWaalsContact O-N 3.11Å; L51-K99 HydrophobicContact CD1-CB 4.02Å; L51-K99 HydrophobicContact CD1-CD 4.12Å; L51-Y151 HydrophobicContact CD1-CD2 4.5Å; L51-Y151 HydrophobicContact CD2-CD2 4.21Å
52	Q	68.1	Low	64.9	Low	48 Å²	48	62.5 Å²	62.5	22%	0.224	32%	0.316	C	S	.	.	H	α-helix	trans	-66	-43.8	172.1	-75.8	171.9	40.1	0	0	110.8	P48 D49 Y50 R55 A56	P48-Q52 WeakPolarHBondContact O-CB 3.43Å; P48-Q52 WeakPolarHBondContact O-CG 3.47Å; P48-Q52 PolarHBondContact O-N 3.34Å; P48-Q52 VanDerWaalsContact O-N 3.11Å; P48-Q52 PolarHBondContact O-NE2 2.88Å; D49-Q52 WeakPolarHBondContact O-CB 3.5Å; D49-Q52 PolarHBondContact O-N 2.92Å; Y50-Q52 VanDerWaalsContact C-N 3.3Å; Y50-Q52 PolarHBondContact O-N 3.39Å; Q52-R55 PolarHBondContact O-N 3.01Å; Q52-A56 VanDerWaalsContact O-CB 3.29Å; Q52-A56 WeakPolarHBondContact O-CB 3.41Å; Q52-A56 PolarHBondContact O-N 2.76Å
53	N	68	Low	62.2	Low	74 Å²	74	70.1 Å²	70.1	40%	0.396	35%	0.346	S	S	.	.	H	α-helix	trans	-63.8	-45.1	177.6	-70.5	-31.7	0	0	0	112.1	D49 Y50 R55 A56 M57	D49-N53 PolarHBondContact O-N 3.43Å; D49-N53 PolarHBondContact O-ND2 2.85Å; D49-N53 PolarHBondContact OD2-ND2 3.25Å; Y50-N53 PolarHBondContact O-N 3.35Å; N53-R55 PolarHBondContact O-N 3.08Å; N53-A56 PolarHBondContact O-N 3.5Å; N53-M57 VanDerWaalsContact O-CG 3.31Å; N53-M57 WeakPolarHBondContact O-CG 3.42Å; N53-M57 PolarHBondContact O-N 2.96Å
54	L	68	Low	59.4	Low	44 Å²	44	80.4 Å²	80.4	23%	0.23	39%	0.385	C	S	.	.	H	α-helix	trans	-57.9	-46.7	174.5	-76.2	179.6	0	0	0	112	Y50 L51 M57 D58 S149	Y50-L54 HydrophobicContact CD1-CD1 3.87Å; Y50-L54 HydrophobicContact CD1-CG 4.27Å; Y50-L54 HydrophobicContact CE1-CD1 3.28Å; Y50-L54 HydrophobicContact CE1-CD2 4.38Å; Y50-L54 HydrophobicContact CE1-CG 3.78Å; Y50-L54 PolarHBondContact O-N 3.22Å; L51-L54 HydrophobicContact CD2-CD1 4.44Å; L54-M57 WeakPolarHBondContact O-CB 3.45Å; L54-M57 PolarHBondContact O-N 3.28Å; L54-D58 PolarHBondContact O-N 3.18Å; L54-S149 WeakPolarHBondContact CD1-O 3.48Å
55	R	60.8	Low	57.3	Low	62 Å²	62	82.1 Å²	82.1	23%	0.234	39%	0.391	C	S	.	.	H	α-helix	trans	-68.3	-37.4	177	-73.2	-169.1	-158.6	-155.1	6.8	112.5	L51 Q52 N53 M57 D58 T59	L51-R55 WeakPolarHBondContact O-CG 3.17Å; L51-R55 PolarHBondContact O-N 3.49Å; L51-R55 VanDerWaalsContact O-N 3.11Å; Q52-R55 PolarHBondContact O-N 3.01Å; N53-R55 PolarHBondContact O-N 3.08Å; R55-M57 PolarHBondContact O-N 2.87Å; R55-D58 PolarHBondContact O-N 3.22Å; R55-T59 WeakPolarHBondContact O-CB 3.07Å; R55-T59 PolarHBondContact O-N 3.44Å; R55-T59 PolarHBondContact O-OG1 3Å
56	A	57.6	Low	55	Low	50 Å²	50	85.9 Å²	85.9	41%	0.413	41%	0.409	S	S	.	.	H	α-helix	trans	-62.5	-33.6	177.1	0	0	0	0	0	111.1	Q52 N53 R60	Q52-A56 VanDerWaalsContact O-CB 3.29Å; Q52-A56 WeakPolarHBondContact O-CB 3.41Å; Q52-A56 PolarHBondContact O-N 2.76Å; N53-A56 PolarHBondContact O-N 3.5Å; A56-R60 WeakPolarHBondContact O-CB 3.38Å; A56-R60 WeakPolarHBondContact O-CG 3.42Å; A56-R60 PolarHBondContact O-N 3.15Å
57	M	54.8	Low	53.3	Low	131 Å²	131	90.7 Å²	90.7	65%	0.645	45%	0.448	S	S	*	.	H	α-helix	trans	-68.3	-45.9	171.7	-67.8	176.7	72.2	0	0	112.1	N53 L54 R55 T59 R60	N53-M57 VanDerWaalsContact O-CG 3.31Å; N53-M57 WeakPolarHBondContact O-CG 3.42Å; N53-M57 PolarHBondContact O-N 2.96Å; L54-M57 WeakPolarHBondContact O-CB 3.45Å; L54-M57 PolarHBondContact O-N 3.28Å; R55-M57 PolarHBondContact O-N 2.87Å; M57-T59 PolarHBondContact O-N 3.44Å; M57-R60 PolarHBondContact O-N 2.94Å
58	D	53.1	Low	51.5	Low	108 Å²	108	96.1 Å²	96.1	58%	0.578	48%	0.482	S	S	*	.	H	α-helix	trans	-63.1	-40.1	174.8	-72.5	-23.2	0	0	0	112.1	L54 R55 Q61	L54-D58 PolarHBondContact O-N 3.18Å; R55-D58 PolarHBondContact O-N 3.22Å; D58-Q61 WeakPolarHBondContact O-CB 3.48Å; D58-Q61 PolarHBondContact O-N 3.34Å
59	T	47.5	Very low	49.4	Very low	52 Å²	52	102.5 Å²	102.5	32%	0.319	51%	0.508	S	S	.	.	H	α-helix	trans	-77.8	-29.1	-176.6	-38.3	0	0	0	0	111.6	R55 M57 Q61 I62 Y63	R55-T59 WeakPolarHBondContact O-CB 3.07Å; R55-T59 PolarHBondContact O-N 3.44Å; R55-T59 PolarHBondContact O-OG1 3Å; M57-T59 PolarHBondContact O-N 3.44Å; T59-Q61 PolarHBondContact O-N 3.34Å; T59-I62 PolarHBondContact O-N 3.15Å; T59-Y63 HydrophobicContact CG2-CD2 4.16Å; T59-Y63 HydrophobicContact CG2-CE2 3.59Å; T59-Y63 VanDerWaalsContact O-CD2 3.25Å; T59-Y63 WeakPolarHBondContact O-CD2 3.19Å; T59-Y63 PolarHBondContact O-N 3.2Å
60	R	37.8	Very low	47.6	Very low	210 Å²	210	105.3 Å²	105.3	79%	0.792	53%	0.528	S	S	*	.	H	α-helix	trans	-58.7	-25.6	169.6	-91.9	-173.3	176.4	-171.5	1	112.4	A56 M57 I62	A56-R60 WeakPolarHBondContact O-CB 3.38Å; A56-R60 WeakPolarHBondContact O-CG 3.42Å; A56-R60 PolarHBondContact O-N 3.15Å; M57-R60 PolarHBondContact O-N 2.94Å; R60-I62 VanDerWaalsContact C-N 3.33Å
61	Q	31.6	Very low	45.2	Very low	149 Å²	149	113 Å²	113	70%	0.696	56%	0.562	S	S	*	*	T	Hydrogen-bonded Turn	trans	-72.6	-23	172.1	-69.8	-170.6	-20.7	0	0	113.6	D58 T59	D58-Q61 WeakPolarHBondContact O-CB 3.48Å; D58-Q61 PolarHBondContact O-N 3.34Å; T59-Q61 PolarHBondContact O-N 3.34Å
62	I	35.3	Very low	43.3	Very low	142 Å²	142	121.2 Å²	121.2	73%	0.728	60%	0.6	S	S	*	*	T	Hydrogen-bonded Turn	trans	-89.2	-19.3	178.1	-58.4	178.9	0	0	0	111.7	T59 R60 W64	T59-I62 PolarHBondContact O-N 3.15Å; R60-I62 VanDerWaalsContact C-N 3.33Å; I62-W64 PolarHBondContact O-N 3.01Å; I62-W64 VanDerWaalsContact O-N 3.1Å
63	Y	33	Very low	41.4	Very low	160 Å²	160	127.3 Å²	127.3	63%	0.627	63%	0.633	S	S	*	*			trans	-85.2	53.2	168.5	-62.6	-71.5	0	0	0	112.6	T59 I65	T59-Y63 HydrophobicContact CG2-CD2 4.16Å; T59-Y63 HydrophobicContact CG2-CE2 3.59Å; T59-Y63 VanDerWaalsContact O-CD2 3.25Å; T59-Y63 WeakPolarHBondContact O-CD2 3.19Å; T59-Y63 PolarHBondContact O-N 3.2Å; Y63-I65 HydrophobicContact CD1-CD1 3.84Å; Y63-I65 HydrophobicContact CD1-CG1 4.02Å; Y63-I65 PolarHBondContact O-N 2.9Å
64	W	26.6	Very low	39.4	Very low	217 Å²	217	133.1 Å²	133.1	82%	0.822	66%	0.655	S	S	*	*			trans	-74.4	76.6	143.4	-72.4	104.1	0	0	0	107.3	I62 N66	I62-W64 PolarHBondContact O-N 3.01Å; I62-W64 VanDerWaalsContact O-N 3.1Å; W64-N66 PolarHBondContact O-N 2.96Å
65	I	35.7	Very low	37.5	Very low	101 Å²	101	138 Å²	138	52%	0.518	68%	0.682	S	S	.	*			trans	-76.5	93	162.7	-54.6	173	0	0	0	104.5	Y63 A67 T70	Y63-I65 HydrophobicContact CD1-CD1 3.84Å; Y63-I65 HydrophobicContact CD1-CG1 4.02Å; Y63-I65 PolarHBondContact O-N 2.9Å; I65-A67 PolarHBondContact O-N 3.37Å; I65-T70 HydrophobicContact CG2-CG2 4.01Å
66	N	29.6	Very low	36.1	Very low	124 Å²	124	143.5 Å²	143.5	66%	0.663	71%	0.71	S	S	*	*			trans	-46.2	115.8	157.4	-83.2	-20.4	0	0	0	105.9	W64 T68 H69	W64-N66 PolarHBondContact O-N 2.96Å; N66-T68 PolarHBondContact O-N 3.3Å; N66-H69 PolarHBondContact O-N 2.81Å
67	A	42.7	Very low	34.6	Very low	102 Å²	102	148.3 Å²	148.3	84%	0.843	73%	0.729	S	S	*	*	T	Hydrogen-bonded Turn	trans	-65	22.8	-168.7	0	0	0	0	0	114.3	I65	I65-A67 PolarHBondContact O-N 3.37Å
68	T	41.3	Very low	33.4	Very low	114 Å²	114	148.9 Å²	148.9	70%	0.699	73%	0.728	S	S	*	*	T	Hydrogen-bonded Turn	trans	-131.2	-9.2	-175.4	49.5	0	0	0	0	115	N66	N66-T68 PolarHBondContact O-N 3.3Å
69	H	28.6	Very low	32.1	Very low	165 Å²	165	151 Å²	151	76%	0.764	74%	0.738	S	S	*	*			trans	-146.6	81.4	174.8	-77.4	-72.7	0	0	0	114	N66 K71	N66-H69 PolarHBondContact O-N 2.81Å; H69-K71 VanDerWaalsContact C-N 3.26Å; H69-K71 PolarHBondContact O-N 3.28Å
70	T	33.1	Very low	31.3	Very low	117 Å²	117	156.6 Å²	156.6	72%	0.718	76%	0.758	S	S	*	*			trans	-75.3	81.7	155.2	37	0	0	0	0	108.8	I65 Q72	I65-T70 HydrophobicContact CG2-CG2 4.01Å; T70-Q72 PolarHBondContact O-N 3.22Å; T70-Q72 VanDerWaalsContact O-N 3.07Å
71	K	25.2	Very low	30.9	Very low	194 Å²	194	152.2 Å²	152.2	84%	0.843	75%	0.75	S	S	*	*			trans	-69.2	107.3	165.3	-138.5	178.8	-172.7	-180	0	106.7	H69 L73	H69-K71 VanDerWaalsContact C-N 3.26Å; H69-K71 PolarHBondContact O-N 3.28Å; K71-L73 PolarHBondContact O-N 3.11Å
72	Q	30.7	Very low	31.2	Very low	181 Å²	181	155.1 Å²	155.1	85%	0.846	76%	0.76	S	S	*	*			trans	-45.8	108.9	176.5	-70.1	176.1	-35.4	0	0	109.9	T70 K74	T70-Q72 PolarHBondContact O-N 3.22Å; T70-Q72 VanDerWaalsContact O-N 3.07Å; Q72-K74 PolarHBondContact O-N 3.09Å; Q72-K74 VanDerWaalsContact O-N 3.13Å
73	L	28.9	Very low	31.3	Very low	177 Å²	177	152.8 Å²	152.8	93%	0.927	76%	0.757	S	S	*	*			trans	-69.1	107.1	161.7	-81.2	158.5	0	0	0	105.9	K71 D75	K71-L73 PolarHBondContact O-N 3.11Å; L73-D75 PolarHBondContact O-N 3.26Å
74	K	26.3	Very low	31.4	Very low	195 Å²	195	152.2 Å²	152.2	85%	0.848	76%	0.764	S	S	*	*			trans	-59.4	101.4	168.6	-87.5	-177.9	168.5	-174.4	0	108.2	Q72	Q72-K74 PolarHBondContact O-N 3.09Å; Q72-K74 VanDerWaalsContact O-N 3.13Å
75	D	28.6	Very low	31.8	Very low	148 Å²	148	145.3 Å²	145.3	79%	0.791	76%	0.761	S	S	*	*			trans	-144.9	117.6	146.1	-134.9	-10.4	0	0	0	108	L73 N77	L73-D75 PolarHBondContact O-N 3.26Å; D75-N77 VanDerWaalsContact C-N 3.26Å; D75-N77 PolarHBondContact O-N 2.96Å
76	E	30.5	Very low	31.8	Very low	177 Å²	177	147 Å²	147	83%	0.827	77%	0.771	S	S	*	*	S	Bend	trans	-73.4	27.6	-150.7	-72.6	-174.2	151.9	0	0	116.9
77	N	26.8	Very low	32.3	Very low	151 Å²	151	146.3 Å²	146.3	81%	0.807	76%	0.76	S	S	*	*			trans	-134.6	37.5	-173.5	-75.1	-45.4	0	0	0	116.5	D75	D75-N77 VanDerWaalsContact C-N 3.26Å; D75-N77 PolarHBondContact O-N 2.96Å
78	F	28.4	Very low	32	Very low	142 Å²	142	148.1 Å²	148.1	62%	0.623	75%	0.749	S	S	*	*			trans	-115.4	93.4	165.9	-83.9	-86.2	0	0	0	112.2	F80 L89	F78-F80 HydrophobicContact CB-CE2 4.33Å; F78-F80 PolarHBondContact O-N 2.71Å; F78-L89 HydrophobicContact CZ-CD1 4.21Å
79	I	26	Very low	32.1	Very low	153 Å²	153	146.3 Å²	146.3	79%	0.785	73%	0.734	S	S	*	*			trans	-76.3	107.8	163.9	-61.6	174.2	0	0	0	107.7	N81	I79-N81 PolarHBondContact O-N 3.25Å
80	F	30.4	Very low	32.7	Very low	169 Å²	169	146.7 Å²	146.7	74%	0.741	73%	0.734	S	S	*	*			trans	-76.6	106.9	172.5	-82.3	-93.7	0	0	0	110	F78	F78-F80 HydrophobicContact CB-CE2 4.33Å; F78-F80 PolarHBondContact O-N 2.71Å
81	N	29.9	Very low	33.4	Very low	118 Å²	118	150.4 Å²	150.4	63%	0.631	74%	0.735	S	S	*	*			trans	-108	97.5	170.5	-130.4	1.1	0	0	0	110.7	I79 S83 Y87	I79-N81 PolarHBondContact O-N 3.25Å; N81-S83 PolarHBondContact O-N 2.95Å; N81-Y87 WeakPolarHBondContact CA-OH 3.36Å; N81-Y87 PolarHBondContact N-OH 3.29Å; N81-Y87 PolarHBondContact O-OH 2.86Å
82	K	38.1	Very low	34.3	Very low	211 Å²	211	144.2 Å²	144.2	92%	0.917	71%	0.711	S	S	*	*	T	Hydrogen-bonded Turn	trans	-71.4	35.7	-169	-161.3	-171.5	172.6	177.1	0	114.9
83	S	37.4	Very low	35.3	Very low	93 Å²	93	138.3 Å²	138.3	65%	0.65	68%	0.684	S	S	*	*	T	Hydrogen-bonded Turn	trans	-116.7	1.4	-174.5	78.8	0	0	0	0	116.9	N81	N81-S83 PolarHBondContact O-N 2.95Å
84	N	33.9	Very low	36.5	Very low	147 Å²	147	134.2 Å²	134.2	79%	0.786	66%	0.66	S	S	*	*	S	Bend	trans	-172.8	115.1	157.9	-88.6	-25	0	0	0	106.7	D86	N84-D86 PolarHBondContact O-N 2.87Å
85	G	35.1	Very low	37.8	Very low	73 Å²	73	129.6 Å²	129.6	75%	0.753	64%	0.641	S	S	*	*			trans	-71.9	35.1	-163.5	0	0	0	0	0	117.4	Y87	G85-Y87 PolarHBondContact O-N 3.3Å
86	D	35.9	Very low	39.3	Very low	135 Å²	135	122.8 Å²	122.8	72%	0.722	61%	0.605	S	S	*	*			trans	-100.9	63.4	179.3	-79.8	-23.9	0	0	0	112.1	N84 K88	N84-D86 PolarHBondContact O-N 2.87Å; D86-K88 PolarHBondContact O-N 3.4Å; D86-K88 VanDerWaalsContact O-N 3.11Å
87	Y	40	Very low	40.9	Very low	111 Å²	111	118 Å²	118	44%	0.435	58%	0.583	S	S	.	*			trans	-82	67.2	157	-40.1	-77.1	0	0	0	108.5	N81 G85 L89	N81-Y87 WeakPolarHBondContact CA-OH 3.36Å; N81-Y87 PolarHBondContact N-OH 3.29Å; N81-Y87 PolarHBondContact O-OH 2.86Å; G85-Y87 PolarHBondContact O-N 3.3Å; Y87-L89 PolarHBondContact O-N 3Å; Y87-L89 VanDerWaalsContact O-N 3.14Å
88	K	36.7	Very low	43	Very low	139 Å²	139	114.5 Å²	114.5	60%	0.604	57%	0.567	S	S	*	*			trans	-68.8	110.7	165.4	-79	-171.1	176.3	-172.9	0	107.3	D86 K90	D86-K88 PolarHBondContact O-N 3.4Å; D86-K88 VanDerWaalsContact O-N 3.11Å; K88-K90 PolarHBondContact O-N 3.28Å
89	L	44.7	Very low	45.2	Very low	77 Å²	77	110.4 Å²	110.4	40%	0.403	55%	0.549	S	S	.	.			trans	-54.4	110.6	-171.4	-146	79.9	0	0	0	110.9	F78 Y87 W91 L92	F78-L89 HydrophobicContact CZ-CD1 4.21Å; Y87-L89 PolarHBondContact O-N 3Å; Y87-L89 VanDerWaalsContact O-N 3.14Å; L89-W91 PolarHBondContact O-N 3.17Å; L89-L92 HydrophobicContact CB-CB 4.39Å; L89-L92 HydrophobicContact CB-CD1 3.65Å; L89-L92 HydrophobicContact CB-CG 3.9Å; L89-L92 HydrophobicContact CD2-CD1 4.27Å; L89-L92 HydrophobicContact CD2-CG 4.09Å; L89-L92 WeakPolarHBondContact O-CB 3.12Å; L89-L92 PolarHBondContact O-N 3.37Å
90	K	41.2	Very low	47.6	Very low	172 Å²	172	104.1 Å²	104.1	75%	0.748	52%	0.517	S	S	*	.	H	α-helix	trans	-50.1	-33.4	179.1	-174.1	176.1	-178.8	176.8	0	113.6	K88 L92 I93 H94	K88-K90 PolarHBondContact O-N 3.28Å; K90-L92 PolarHBondContact O-N 2.96Å; K90-I93 PolarHBondContact O-N 3.41Å; K90-H94 PolarHBondContact O-N 2.87Å
91	W	46.3	Very low	49.9	Very low	196 Å²	196	96.9 Å²	96.9	74%	0.742	49%	0.49	S	S	*	.	H	α-helix	trans	-66.2	-31.6	175.8	-60.6	115.5	0	0	0	113.9	L89 I93 Q95	L89-W91 PolarHBondContact O-N 3.17Å; W91-I93 VanDerWaalsContact C-N 3.34Å; W91-Q95 WeakPolarHBondContact O-CB 3.44Å; W91-Q95 VanDerWaalsContact O-CG 3.26Å; W91-Q95 WeakPolarHBondContact O-CG 3.34Å; W91-Q95 PolarHBondContact O-N 3.37Å; W91-Q95 VanDerWaalsContact O-N 3.11Å
92	L	45.5	Very low	52.5	Low	64 Å²	64	94 Å²	94	34%	0.335	48%	0.477	S	S	.	.	H	α-helix	trans	-67.9	-36.9	175.6	-70.3	168.8	0	0	0	111.2	L89 K90 S96	L89-L92 HydrophobicContact CB-CB 4.39Å; L89-L92 HydrophobicContact CB-CD1 3.65Å; L89-L92 HydrophobicContact CB-CG 3.9Å; L89-L92 HydrophobicContact CD2-CD1 4.27Å; L89-L92 HydrophobicContact CD2-CG 4.09Å; L89-L92 WeakPolarHBondContact O-CB 3.12Å; L89-L92 PolarHBondContact O-N 3.37Å; K90-L92 PolarHBondContact O-N 2.96Å; L92-S96 WeakPolarHBondContact O-CB 3.08Å; L92-S96 PolarHBondContact O-N 3.15Å
93	I	51.4	Low	54.8	Low	56 Å²	56	84 Å²	84	29%	0.287	43%	0.434	S	S	.	.	H	α-helix	trans	-65.6	-51.2	177.3	-60.6	169.1	0	0	0	109.7	K90 W91 Q95 S96 E97	K90-I93 PolarHBondContact O-N 3.41Å; W91-I93 VanDerWaalsContact C-N 3.34Å; I93-Q95 VanDerWaalsContact C-N 3.32Å; I93-Q95 PolarHBondContact O-N 3.35Å; I93-S96 WeakPolarHBondContact O-CA 3.44Å; I93-S96 WeakPolarHBondContact O-CB 3.45Å; I93-S96 PolarHBondContact O-N 3.37Å; I93-S96 PolarHBondContact O-OG 2.7Å; I93-E97 PolarHBondContact O-N 3Å
94	H	52.5	Low	57	Low	92 Å²	92	80.7 Å²	80.7	43%	0.426	41%	0.407	S	S	.	.	H	α-helix	trans	-59.7	-41.7	179.7	-168.8	58.5	0	0	0	112.7	K90 S96 E97 T98	K90-H94 PolarHBondContact O-N 2.87Å; H94-S96 VanDerWaalsContact C-N 3.25Å; H94-S96 PolarHBondContact O-N 3.48Å; H94-E97 IonicContact ND1-OE2 3.49Å; H94-E97 PolarHBondContact ND1-OE2 3.45Å; H94-E97 PolarHBondContact O-N 2.78Å; H94-T98 PolarHBondContact O-N 2.98Å; H94-T98 VanDerWaalsContact O-N 3.15Å; H94-T98 PolarHBondContact O-OG1 3.29Å
95	Q	54.1	Low	59.7	Low	97 Å²	97	73.9 Å²	73.9	45%	0.453	37%	0.372	S	S	.	.	H	α-helix	trans	-65.2	-26.9	174	-75.6	-76.3	-31.6	0	0	113.4	W91 I93 K99	W91-Q95 WeakPolarHBondContact O-CB 3.44Å; W91-Q95 VanDerWaalsContact O-CG 3.26Å; W91-Q95 WeakPolarHBondContact O-CG 3.34Å; W91-Q95 PolarHBondContact O-N 3.37Å; W91-Q95 VanDerWaalsContact O-N 3.11Å; I93-Q95 VanDerWaalsContact C-N 3.32Å; I93-Q95 PolarHBondContact O-N 3.35Å; Q95-K99 WeakPolarHBondContact O-CG 3.36Å
96	S	60.3	Low	62.4	Low	5 Å²	5	72.7 Å²	72.7	4%	0.035	35%	0.346	C	S	.	.	H	α-helix	trans	-76.2	-39.5	174	75	0	0	0	0	111.6	L92 I93 H94 K99 I100	L92-S96 WeakPolarHBondContact O-CB 3.08Å; L92-S96 PolarHBondContact O-N 3.15Å; I93-S96 WeakPolarHBondContact O-CA 3.44Å; I93-S96 WeakPolarHBondContact O-CB 3.45Å; I93-S96 PolarHBondContact O-N 3.37Å; I93-S96 PolarHBondContact O-OG 2.7Å; H94-S96 VanDerWaalsContact C-N 3.25Å; H94-S96 PolarHBondContact O-N 3.48Å; S96-K99 PolarHBondContact O-N 3.05Å; S96-I100 WeakPolarHBondContact O-CD1 3.49Å; S96-I100 WeakPolarHBondContact O-CG1 3.38Å; S96-I100 PolarHBondContact O-N 3.4Å
97	E	65	Low	65.2	Low	77 Å²	77	67 Å²	67	36%	0.36	32%	0.315	S	S	.	.	H	α-helix	trans	-59.6	-47.9	175.8	-68.5	169.1	179.7	0	0	111.7	I93 H94 K99 I100 G101	I93-E97 PolarHBondContact O-N 3Å; H94-E97 IonicContact ND1-OE2 3.49Å; H94-E97 PolarHBondContact ND1-OE2 3.45Å; H94-E97 PolarHBondContact O-N 2.78Å; E97-K99 VanDerWaalsContact C-N 3.29Å; E97-K99 PolarHBondContact O-N 3.05Å; E97-I100 PolarHBondContact O-N 2.93Å; E97-G101 PolarHBondContact O-N 2.81Å
98	T	70.5	Confident	67.8	Low	77 Å²	77	61.9 Å²	61.9	47%	0.472	30%	0.296	S	S	.	.	H	α-helix	trans	-59.7	-40.4	176.7	-48.5	0	0	0	0	111.9	H94 T102	H94-T98 PolarHBondContact O-N 2.98Å; H94-T98 VanDerWaalsContact O-N 3.15Å; H94-T98 PolarHBondContact O-OG1 3.29Å; T98-T102 WeakPolarHBondContact O-CB 3.29Å; T98-T102 PolarHBondContact O-N 3.48Å; T98-T102 PolarHBondContact O-OG1 3.48Å
99	K	75.2	Confident	70.7	Confident	57 Å²	57	57.9 Å²	57.9	25%	0.248	28%	0.28	C	S	.	.	H	α-helix	trans	-66.8	-37.5	177.8	-78.7	-174.1	177.8	-168.4	0	112.3	L51 Q95 S96 E97 T102 L103 Y151	L51-K99 HydrophobicContact CD1-CB 4.02Å; L51-K99 HydrophobicContact CD1-CD 4.12Å; Q95-K99 WeakPolarHBondContact O-CG 3.36Å; S96-K99 PolarHBondContact O-N 3.05Å; E97-K99 VanDerWaalsContact C-N 3.29Å; E97-K99 PolarHBondContact O-N 3.05Å; K99-T102 PolarHBondContact O-N 2.9Å; K99-L103 WeakPolarHBondContact O-CG 3.35Å; K99-L103 PolarHBondContact O-N 3.07Å; K99-L103 VanDerWaalsContact O-N 3.08Å; K99-Y151 HydrophobicContact CB-CE2 3.69Å; K99-Y151 HydrophobicContact CD-CD2 4.12Å; K99-Y151 HydrophobicContact CD-CE2 4Å; K99-Y151 HydrophobicContact CG-CE2 3.92Å; K99-Y151 PolarHBondContact O-OH 3.44Å; K99-Y151 VanDerWaalsContact O-OH 3.14Å
100	I	75.2	Confident	73.2	Confident	20 Å²	20	56 Å²	56	10%	0.103	27%	0.27	C	S	.	.	H	α-helix	trans	-68.5	-47.9	176.1	-67.4	158	0	0	0	110.4	I43 I47 P48 S96 E97 T102 L103 F104	I43-I100 HydrophobicContact CD1-CG2 4Å; I47-I100 HydrophobicContact CB-CG1 4.29Å; I47-I100 HydrophobicContact CG2-CD1 4.46Å; I47-I100 HydrophobicContact CG2-CG1 3.71Å; P48-I100 HydrophobicContact CB-CD1 3.91Å; P48-I100 HydrophobicContact CG-CD1 3.46Å; P48-I100 VanDerWaalsContact CG-CD1 3.46Å; S96-I100 WeakPolarHBondContact O-CD1 3.49Å; S96-I100 WeakPolarHBondContact O-CG1 3.38Å; S96-I100 PolarHBondContact O-N 3.4Å; E97-I100 PolarHBondContact O-N 2.93Å; I100-T102 PolarHBondContact O-N 3.36Å; I100-L103 WeakPolarHBondContact O-CB 3.23Å; I100-L103 PolarHBondContact O-N 2.8Å; I100-F104 HydrophobicContact CG2-CD2 3.72Å; I100-F104 HydrophobicContact CG2-CE2 3.37Å; I100-F104 HydrophobicContact CG2-CZ 4.24Å; I100-F104 WeakPolarHBondContact O-CD2 3.32Å; I100-F104 PolarHBondContact O-N 3.33Å
101	G	78.3	Confident	75.9	Confident	18 Å²	18	48.3 Å²	48.3	19%	0.186	24%	0.237	C	C	.	.	H	α-helix	trans	-56.7	-38.7	174.7	0	0	0	0	0	112.2	E97 F104 A105	E97-G101 PolarHBondContact O-N 2.81Å; G101-F104 PolarHBondContact O-N 3.25Å; G101-A105 WeakPolarHBondContact O-CB 3.46Å; G101-A105 PolarHBondContact O-N 3.16Å
102	T	85	Confident	78.3	Confident	58 Å²	58	40.9 Å²	40.9	36%	0.356	21%	0.212	S	C	.	.	H	α-helix	trans	-64.5	-40.9	173.9	-57.4	0	0	0	0	112.2	T98 K99 I100 F104 F106 F155	T98-T102 WeakPolarHBondContact O-CB 3.29Å; T98-T102 PolarHBondContact O-N 3.48Å; T98-T102 PolarHBondContact O-OG1 3.48Å; K99-T102 PolarHBondContact O-N 2.9Å; I100-T102 PolarHBondContact O-N 3.36Å; T102-F104 VanDerWaalsContact C-N 3.35Å; T102-F106 VanDerWaalsContact O-CB 3.26Å; T102-F106 WeakPolarHBondContact O-CB 3.27Å; T102-F106 PolarHBondContact O-N 3.46Å; T102-F155 HydrophobicContact CG2-CD2 4.32Å; T102-F155 HydrophobicContact CG2-CE2 3.85Å
103	L	86.9	Confident	80.8	Confident	0 Å²	0	43.1 Å²	43.1	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-65.6	-37.1	176.5	-72.4	172.9	0	0	0	112.2	I47 K99 I100 K107 Y151 M154 F155 R158	I47-L103 HydrophobicContact CG2-CD1 4.08Å; K99-L103 WeakPolarHBondContact O-CG 3.35Å; K99-L103 PolarHBondContact O-N 3.07Å; K99-L103 VanDerWaalsContact O-N 3.08Å; I100-L103 WeakPolarHBondContact O-CB 3.23Å; I100-L103 PolarHBondContact O-N 2.8Å; L103-K107 PolarHBondContact O-N 3.33Å; L103-Y151 HydrophobicContact CD1-CE2 4.07Å; L103-Y151 HydrophobicContact CD2-CE2 4.16Å; L103-Y151 HydrophobicContact CG-CE2 3.99Å; L103-M154 HydrophobicContact CD2-CB 4.49Å; L103-F155 HydrophobicContact CD2-CB 4.17Å; L103-F155 HydrophobicContact CD2-CD2 4.27Å; L103-R158 HydrophobicContact CB-CG 4.23Å; L103-R158 HydrophobicContact CD2-CB 4.49Å; L103-R158 HydrophobicContact CD2-CG 3.95Å
104	F	83.9	Confident	83.1	Confident	23 Å²	23	41.4 Å²	41.4	10%	0.101	22%	0.216	C	C	.	.	H	α-helix	trans	-66.7	-53.1	173.6	-73.2	-50	0	0	0	112.2	Y40 I43 V44 I100 G101 T102 F106 K107 A108	Y40-F104 HydrophobicContact CD1-CE1 4.25Å; Y40-F104 AromaticContact CD2-CD1 3.58Å; Y40-F104 HydrophobicContact CD2-CD1 3.58Å; Y40-F104 AromaticContact CD2-CE1 3.77Å; Y40-F104 HydrophobicContact CD2-CE1 3.77Å; Y40-F104 HydrophobicContact CE1-CD1 4.38Å; Y40-F104 HydrophobicContact CE1-CE1 4.09Å; Y40-F104 HydrophobicContact CE2-CB 4.15Å; Y40-F104 AromaticContact CE2-CD1 3.15Å; Y40-F104 HydrophobicContact CE2-CD1 3.15Å; Y40-F104 AromaticContact CE2-CE1 3.61Å; Y40-F104 HydrophobicContact CE2-CE1 3.61Å; Y40-F104 AromaticContact CE2-CG 3.92Å; Y40-F104 HydrophobicContact CE2-CG 3.92Å; Y40-F104 HydrophobicContact CG-CD1 4.36Å; Y40-F104 HydrophobicContact CG-CE1 4.09Å; Y40-F104 AromaticContact CZ-CD1 3.61Å; Y40-F104 AromaticContact CZ-CE1 3.76Å; Y40-F104 VanDerWaalsContact O-CE1 3.28Å; Y40-F104 WeakPolarHBondContact O-CE1 3.3Å; I43-F104 HydrophobicContact CD1-CD1 4.06Å; I43-F104 HydrophobicContact CD1-CD2 4.47Å; I43-F104 HydrophobicContact CD1-CE1 3.36Å; I43-F104 HydrophobicContact CD1-CE2 3.82Å; I43-F104 HydrophobicContact CD1-CZ 3.22Å; I43-F104 HydrophobicContact CG1-CE1 3.6Å; I43-F104 HydrophobicContact CG1-CZ 3.73Å; V44-F104 HydrophobicContact CG2-CE2 4.31Å; V44-F104 HydrophobicContact CG2-CZ 3.66Å; I100-F104 HydrophobicContact CG2-CD2 3.72Å; I100-F104 HydrophobicContact CG2-CE2 3.37Å; I100-F104 HydrophobicContact CG2-CZ 4.24Å; I100-F104 WeakPolarHBondContact O-CD2 3.32Å; I100-F104 PolarHBondContact O-N 3.33Å; G101-F104 PolarHBondContact O-N 3.25Å; T102-F104 VanDerWaalsContact C-N 3.35Å; F104-F106 VanDerWaalsContact C-N 3.29Å; F104-F106 PolarHBondContact O-N 3.21Å; F104-K107 PolarHBondContact O-N 3.08Å; F104-A108 PolarHBondContact O-N 3.33Å
105	A	89.2	Confident	85.2	Confident	5 Å²	5	37 Å²	37	4%	0.041	20%	0.196	C	C	.	.	H	α-helix	trans	-60.2	-39.8	-179.4	0	0	0	0	0	111.7	G101 K107 A108 I109 P415 I416	G101-A105 WeakPolarHBondContact O-CB 3.46Å; G101-A105 PolarHBondContact O-N 3.16Å; A105-K107 PolarHBondContact O-N 3.31Å; A105-A108 PolarHBondContact O-N 3.17Å; A105-I109 WeakPolarHBondContact O-CB 3.19Å; A105-I109 VanDerWaalsContact O-CG1 3.23Å; A105-I109 WeakPolarHBondContact O-CG1 3.26Å; A105-I109 PolarHBondContact O-N 3.15Å; A105-P415 HydrophobicContact CB-CB 4.34Å; A105-I416 HydrophobicContact CB-CD1 4.35Å; A105-I416 HydrophobicContact CB-CG1 4.15Å
106	F	93.6	Very high	87.2	Confident	47 Å²	47	34.8 Å²	34.8	21%	0.206	19%	0.19	C	C	.	.	H	α-helix	trans	-66.2	-38.8	-179	-171.2	-121.2	0	0	0	113.1	T102 F104 A108 I109 I110 F155 G159	T102-F106 VanDerWaalsContact O-CB 3.26Å; T102-F106 WeakPolarHBondContact O-CB 3.27Å; T102-F106 PolarHBondContact O-N 3.46Å; F104-F106 VanDerWaalsContact C-N 3.29Å; F104-F106 PolarHBondContact O-N 3.21Å; F106-A108 VanDerWaalsContact C-N 3.35Å; F106-I109 PolarHBondContact O-N 3.47Å; F106-I110 HydrophobicContact CD2-CG1 4.3Å; F106-I110 HydrophobicContact CE1-CG1 4.27Å; F106-I110 HydrophobicContact CE2-CD1 3.84Å; F106-I110 HydrophobicContact CE2-CG1 3.91Å; F106-I110 HydrophobicContact CZ-CD1 3.97Å; F106-I110 HydrophobicContact CZ-CG1 3.89Å; F106-I110 WeakPolarHBondContact O-CG1 3.38Å; F106-I110 PolarHBondContact O-N 3.01Å; F106-F155 HydrophobicContact CB-CD2 4.26Å; F106-F155 HydrophobicContact CB-CE2 3.58Å; F106-F155 HydrophobicContact CB-CZ 4.03Å; F106-F155 HydrophobicContact CD1-CD1 4.03Å; F106-F155 AromaticContact CD1-CD2 3.89Å; F106-F155 HydrophobicContact CD1-CD2 3.89Å; F106-F155 AromaticContact CD1-CE1 3.75Å; F106-F155 HydrophobicContact CD1-CE1 3.75Å; F106-F155 AromaticContact CD1-CE2 3.6Å; F106-F155 HydrophobicContact CD1-CE2 3.6Å; F106-F155 HydrophobicContact CD1-CG 4.1Å; F106-F155 AromaticContact CD1-CZ 3.53Å; F106-F155 HydrophobicContact CD1-CZ 3.53Å; F106-F155 VanDerWaalsContact CD1-O 3.23Å; F106-F155 WeakPolarHBondContact CD1-O 3.26Å; F106-F155 HydrophobicContact CD2-CE1 4.07Å; F106-F155 AromaticContact CD2-CE2 3.9Å; F106-F155 HydrophobicContact CD2-CE2 3.9Å; F106-F155 AromaticContact CD2-CZ 3.39Å; F106-F155 HydrophobicContact CD2-CZ 3.39Å; F106-F155 AromaticContact CE1-CD1 3.8Å; F106-F155 HydrophobicContact CE1-CD1 3.8Å; F106-F155 HydrophobicContact CE1-CD2 4.49Å; F106-F155 AromaticContact CE1-CE1 3.48Å; F106-F155 HydrophobicContact CE1-CE1 3.48Å; F106-F155 VanDerWaalsContact CE1-CE1 3.48Å; F106-F155 HydrophobicContact CE1-CE2 4.23Å; F106-F155 HydrophobicContact CE1-CG 4.3Å; F106-F155 AromaticContact CE1-CZ 3.73Å; F106-F155 HydrophobicContact CE1-CZ 3.73Å; F106-F155 VanDerWaalsContact CE1-O 3.26Å; F106-F155 WeakPolarHBondContact CE1-O 3.41Å; F106-F155 AromaticContact CE2-CE1 3.84Å; F106-F155 HydrophobicContact CE2-CE1 3.84Å; F106-F155 HydrophobicContact CE2-CE2 4.49Å; F106-F155 AromaticContact CE2-CZ 3.61Å; F106-F155 HydrophobicContact CE2-CZ 3.61Å; F106-F155 HydrophobicContact CG-CD2 4.13Å; F106-F155 HydrophobicContact CG-CE1 4.04Å; F106-F155 AromaticContact CG-CE2 3.41Å; F106-F155 HydrophobicContact CG-CE2 3.41Å; F106-F155 VanDerWaalsContact CG-CE2 3.41Å; F106-F155 AromaticContact CG-CZ 3.36Å; F106-F155 HydrophobicContact CG-CZ 3.36Å; F106-F155 HydrophobicContact CZ-CD1 4.26Å; F106-F155 AromaticContact CZ-CE1 3.54Å; F106-F155 HydrophobicContact CZ-CE1 3.54Å; F106-F155 AromaticContact CZ-CZ 3.77Å; F106-F155 HydrophobicContact CZ-CZ 3.77Å; F106-G159 VanDerWaalsContact CE1-CA 3.47Å
107	K	94.5	Very high	89	Confident	15 Å²	15	39.5 Å²	39.5	7%	0.065	21%	0.214	C	C	.	.	H	α-helix	trans	-56.3	-51	171.3	-174.1	-91.5	-173.2	-173	0	110.3	D36 L103 F104 A105 I109 I110 Q111 R158 Q161 G162 S165	D36-K107 IonicContact OD1-NZ 3.48Å; D36-K107 PolarHBondContact OD1-NZ 3.45Å; D36-K107 IonicContact OD2-NZ 2.76Å; D36-K107 PolarHBondContact OD2-NZ 3.3Å; L103-K107 PolarHBondContact O-N 3.33Å; F104-K107 PolarHBondContact O-N 3.08Å; A105-K107 PolarHBondContact O-N 3.31Å; K107-I109 PolarHBondContact O-N 3.28Å; K107-I110 PolarHBondContact O-N 3.42Å; K107-Q111 WeakPolarHBondContact O-CB 3.2Å; K107-Q111 PolarHBondContact O-N 3.23Å; K107-R158 HydrophobicContact CB-CB 4.45Å; K107-Q161 HydrophobicContact CG-CB 4.47Å; K107-G162 WeakPolarHBondContact O-CA 3.3Å; K107-S165 VanDerWaalsContact CE-OG 3.23Å; K107-S165 WeakPolarHBondContact CE-OG 3.38Å; K107-S165 PolarHBondContact NZ-OG 3.29Å
108	A	95	Very high	90.6	Very high	5 Å²	5	35.9 Å²	35.9	4%	0.041	20%	0.197	C	C	.	.	H	α-helix	trans	-65	-38.4	-179.5	0	0	0	0	0	113.2	F104 A105 F106 Q111 L112 A412	F104-A108 PolarHBondContact O-N 3.33Å; A105-A108 PolarHBondContact O-N 3.17Å; F106-A108 VanDerWaalsContact C-N 3.35Å; A108-Q111 PolarHBondContact O-N 2.9Å; A108-L112 VanDerWaalsContact O-CB 3.29Å; A108-L112 WeakPolarHBondContact O-CB 3.14Å; A108-L112 PolarHBondContact O-N 3.27Å; A108-A412 HydrophobicContact CB-CB 4.03Å
109	I	96.6	Very high	91.8	Very high	54 Å²	54	32.2 Å²	32.2	28%	0.277	17%	0.174	S	C	.	.	H	α-helix	trans	-62.8	-47.4	176.1	-71.4	163.1	0	0	0	110.8	A105 F106 K107 Q111 L112 L113 A412 I416	A105-I109 WeakPolarHBondContact O-CB 3.19Å; A105-I109 VanDerWaalsContact O-CG1 3.23Å; A105-I109 WeakPolarHBondContact O-CG1 3.26Å; A105-I109 PolarHBondContact O-N 3.15Å; F106-I109 PolarHBondContact O-N 3.47Å; K107-I109 PolarHBondContact O-N 3.28Å; I109-Q111 VanDerWaalsContact C-N 3.32Å; I109-Q111 PolarHBondContact O-N 3.22Å; I109-L112 WeakPolarHBondContact O-CB 3.42Å; I109-L112 PolarHBondContact O-N 3.29Å; I109-L113 HydrophobicContact CG2-CD1 3.99Å; I109-L113 HydrophobicContact CG2-CG 4.47Å; I109-L113 VanDerWaalsContact O-CG 3.29Å; I109-L113 WeakPolarHBondContact O-CG 3.41Å; I109-L113 PolarHBondContact O-N 2.94Å; I109-A412 HydrophobicContact CG1-CB 3.8Å; I109-I416 HydrophobicContact CD1-CD1 4.02Å
110	I	97.9	Very high	92.8	Very high	38 Å²	38	31.6 Å²	31.6	20%	0.195	18%	0.175	C	C	.	.	H	α-helix	trans	-66	-39.9	179.4	-61.2	-57.4	0	0	0	110.5	F106 K107 L112 L113 C114 G159 M163	F106-I110 HydrophobicContact CD2-CG1 4.3Å; F106-I110 HydrophobicContact CE1-CG1 4.27Å; F106-I110 HydrophobicContact CE2-CD1 3.84Å; F106-I110 HydrophobicContact CE2-CG1 3.91Å; F106-I110 HydrophobicContact CZ-CD1 3.97Å; F106-I110 HydrophobicContact CZ-CG1 3.89Å; F106-I110 WeakPolarHBondContact O-CG1 3.38Å; F106-I110 PolarHBondContact O-N 3.01Å; K107-I110 PolarHBondContact O-N 3.42Å; I110-L112 PolarHBondContact O-N 3.21Å; I110-L113 PolarHBondContact O-N 2.82Å; I110-C114 WeakPolarHBondContact O-CB 3.49Å; I110-C114 PolarHBondContact O-N 2.86Å; I110-C114 PolarHBondContact O-SG 3.08Å; I110-C114 VanDerWaalsContact O-SG 3.33Å; I110-G159 WeakPolarHBondContact CG2-O 3.33Å; I110-M163 HydrophobicContact CG2-CB 3.95Å
111	Q	97.9	Very high	93.9	Very high	10 Å²	10	33 Å²	33	5%	0.047	18%	0.184	C	C	.	.	H	α-helix	trans	-58.1	-49.3	174.4	-169.6	169.6	-8.3	0	0	111.7	K107 A108 I109 L113 C114 N115 G162 A166 D169 D404 S408	K107-Q111 WeakPolarHBondContact O-CB 3.2Å; K107-Q111 PolarHBondContact O-N 3.23Å; A108-Q111 PolarHBondContact O-N 2.9Å; I109-Q111 VanDerWaalsContact C-N 3.32Å; I109-Q111 PolarHBondContact O-N 3.22Å; Q111-L113 VanDerWaalsContact C-N 3.32Å; Q111-L113 PolarHBondContact O-N 2.96Å; Q111-C114 PolarHBondContact O-N 2.91Å; Q111-N115 VanDerWaalsContact O-CG 3.27Å; Q111-N115 PolarHBondContact O-N 3.48Å; Q111-N115 PolarHBondContact O-ND2 2.79Å; Q111-G162 WeakPolarHBondContact CA-O 3.04Å; Q111-G162 WeakPolarHBondContact CB-O 3.39Å; Q111-A166 HydrophobicContact CG-CB 3.99Å; Q111-D169 PolarHBondContact NE2-OD2 3.29Å; Q111-D404 WeakPolarHBondContact CG-OD2 3.44Å; Q111-D404 VanDerWaalsContact NE2-CG 3.3Å; Q111-D404 PolarHBondContact NE2-OD1 2.89Å; Q111-D404 PolarHBondContact NE2-OD2 3.24Å; Q111-S408 VanDerWaalsContact CG-OG 3.24Å; Q111-S408 WeakPolarHBondContact CG-OG 3.28Å
112	L	97	Very high	94.7	Very high	40 Å²	40	32.1 Å²	32.1	21%	0.209	18%	0.176	C	C	.	.	H	α-helix	trans	-53.3	-45.8	175.1	179.2	66.2	0	0	0	112.4	A108 I109 I110 P116 I405 L409	A108-L112 VanDerWaalsContact O-CB 3.29Å; A108-L112 WeakPolarHBondContact O-CB 3.14Å; A108-L112 PolarHBondContact O-N 3.27Å; I109-L112 WeakPolarHBondContact O-CB 3.42Å; I109-L112 PolarHBondContact O-N 3.29Å; I110-L112 PolarHBondContact O-N 3.21Å; L112-P116 WeakPolarHBondContact O-CD 3.38Å; L112-I405 HydrophobicContact CD1-CB 4.26Å; L112-I405 HydrophobicContact CD1-CG1 4.42Å; L112-I405 HydrophobicContact CD1-CG2 3.73Å; L112-L409 HydrophobicContact CD1-CB 4.09Å; L112-L409 HydrophobicContact CD2-CD1 4.07Å
113	L	97.8	Very high	95.3	Very high	111 Å²	111	30 Å²	30	58%	0.581	16%	0.162	S	C	*	.	H	α-helix	trans	-73.3	-32.3	-178.7	-67.3	174.8	0	0	0	112.9	I109 I110 Q111	I109-L113 HydrophobicContact CG2-CD1 3.99Å; I109-L113 HydrophobicContact CG2-CG 4.47Å; I109-L113 VanDerWaalsContact O-CG 3.29Å; I109-L113 WeakPolarHBondContact O-CG 3.41Å; I109-L113 PolarHBondContact O-N 2.94Å; I110-L113 PolarHBondContact O-N 2.82Å; Q111-L113 VanDerWaalsContact C-N 3.32Å; Q111-L113 PolarHBondContact O-N 2.96Å
114	C	98.1	Very high	95.6	Very high	20 Å²	20	39 Å²	39	14%	0.135	20%	0.196	C	C	.	.	H	α-helix	trans	-79.8	-26.6	-179.3	-73.9	0	0	0	0	113.1	I110 Q111 I117 S118 A166	I110-C114 WeakPolarHBondContact O-CB 3.49Å; I110-C114 PolarHBondContact O-N 2.86Å; I110-C114 PolarHBondContact O-SG 3.08Å; I110-C114 VanDerWaalsContact O-SG 3.33Å; Q111-C114 PolarHBondContact O-N 2.91Å; C114-I117 WeakPolarHBondContact O-CA 3.04Å; C114-I117 WeakPolarHBondContact O-CB 3.4Å; C114-I117 PolarHBondContact O-N 3.4Å; C114-S118 PolarHBondContact O-N 2.67Å; C114-A166 HydrophobicContact CB-CB 3.69Å
115	N	97.9	Very high	96	Very high	0 Å²	0	42.3 Å²	42.3	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-60.1	-40.4	-173.5	-83.5	-31.1	0	0	0	116.5	Q111 I117 S118 G119 A166 T170 A401 D404 I405	Q111-N115 VanDerWaalsContact O-CG 3.27Å; Q111-N115 PolarHBondContact O-N 3.48Å; Q111-N115 PolarHBondContact O-ND2 2.79Å; N115-I117 PolarHBondContact O-N 2.96Å; N115-S118 WeakPolarHBondContact CA-OG 3.44Å; N115-S118 PolarHBondContact O-N 3.28Å; N115-S118 PolarHBondContact O-OG 2.9Å; N115-S118 PolarHBondContact OD1-OG 3.39Å; N115-G119 PolarHBondContact O-N 3.34Å; N115-A166 VanDerWaalsContact OD1-CA 3.29Å; N115-A166 WeakPolarHBondContact OD1-CA 3.42Å; N115-A166 WeakPolarHBondContact OD1-CB 3.23Å; N115-A166 PolarHBondContact OD1-O 3.5Å; N115-T170 PolarHBondContact OD1-OG1 3.39Å; N115-A401 WeakPolarHBondContact O-CB 3.28Å; N115-D404 VanDerWaalsContact CG-OD2 3.25Å; N115-D404 VanDerWaalsContact ND2-C 3.35Å; N115-D404 WeakPolarHBondContact ND2-CB 3.4Å; N115-D404 VanDerWaalsContact ND2-CG 3.32Å; N115-D404 PolarHBondContact ND2-OD2 2.94Å; N115-D404 PolarHBondContact OD1-OD2 3.42Å; N115-I405 HydrophobicContact CB-CD1 3.95Å; N115-I405 HydrophobicContact CB-CG1 3.43Å; N115-I405 VanDerWaalsContact CB-CG1 3.43Å; N115-I405 PolarHBondContact ND2-N 3.24Å
116	P	96.6	Very high	96.2	Very high	51 Å²	51	42.1 Å²	42.1	33%	0.331	21%	0.212	S	C	.	.	H	α-helix	trans	-58.1	-33.2	173.9	-25.6	34.4	0	0	0	113.2	L112 T120 I261 I405	L112-P116 WeakPolarHBondContact O-CD 3.38Å; P116-T120 PolarHBondContact O-N 2.97Å; P116-T120 PolarHBondContact O-OG1 3.41Å; P116-I261 HydrophobicContact CB-CD1 4.34Å; P116-I405 HydrophobicContact CG-CD1 3.88Å
117	I	97.4	Very high	96.2	Very high	104 Å²	104	40.3 Å²	40.3	53%	0.533	20%	0.204	S	C	.	.	H	α-helix	trans	-75.7	-47.2	176.5	-57.2	170.6	0	0	0	109.5	C114 N115 G119 T120 V121	C114-I117 WeakPolarHBondContact O-CA 3.04Å; C114-I117 WeakPolarHBondContact O-CB 3.4Å; C114-I117 PolarHBondContact O-N 3.4Å; N115-I117 PolarHBondContact O-N 2.96Å; I117-G119 PolarHBondContact O-N 3.29Å; I117-T120 PolarHBondContact O-N 3.25Å; I117-V121 HydrophobicContact CG2-CG2 4.1Å; I117-V121 WeakPolarHBondContact O-CB 3.03Å; I117-V121 VanDerWaalsContact O-CG2 3.27Å; I117-V121 WeakPolarHBondContact O-CG2 3.49Å; I117-V121 PolarHBondContact O-N 3.32Å
118	S	97.4	Very high	96.2	Very high	0 Å²	0	40 Å²	40	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-57.7	-49	-179.1	75.2	0	0	0	0	111.1	C114 N115 T120 V121 I122 A166	C114-S118 PolarHBondContact O-N 2.67Å; N115-S118 WeakPolarHBondContact CA-OG 3.44Å; N115-S118 PolarHBondContact O-N 3.28Å; N115-S118 PolarHBondContact O-OG 2.9Å; N115-S118 PolarHBondContact OD1-OG 3.39Å; S118-T120 PolarHBondContact O-N 2.96Å; S118-V121 PolarHBondContact O-N 3.09Å; S118-I122 WeakPolarHBondContact O-CB 3.37Å; S118-I122 WeakPolarHBondContact O-CD1 3.15Å; S118-I122 WeakPolarHBondContact O-CG1 3.37Å; S118-I122 PolarHBondContact O-N 3.24Å; S118-A166 VanDerWaalsContact CB-O 3.31Å; S118-A166 WeakPolarHBondContact CB-O 3.44Å; S118-A166 PolarHBondContact OG-O 3.11Å
119	G	96.4	Very high	96.2	Very high	0 Å²	0	43.1 Å²	43.1	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-57.7	-46.2	177.5	0	0	0	0	0	113	N115 I117 V121 I122 D123	N115-G119 PolarHBondContact O-N 3.34Å; I117-G119 PolarHBondContact O-N 3.29Å; G119-V121 PolarHBondContact O-N 2.86Å; G119-I122 PolarHBondContact O-N 2.83Å; G119-D123 VanDerWaalsContact O-CG 3.27Å; G119-D123 PolarHBondContact O-N 3.37Å
120	T	96.3	Very high	96.3	Very high	45 Å²	45	40.7 Å²	40.7	28%	0.276	21%	0.209	S	C	.	.	H	α-helix	trans	-64.8	-39	178.4	-57	0	0	0	0	112.3	P116 I117 S118 R124	P116-T120 PolarHBondContact O-N 2.97Å; P116-T120 PolarHBondContact O-OG1 3.41Å; I117-T120 PolarHBondContact O-N 3.25Å; S118-T120 PolarHBondContact O-N 2.96Å; T120-R124 WeakPolarHBondContact O-CG 3.44Å; T120-R124 PolarHBondContact O-N 2.8Å
121	V	97.4	Very high	96.2	Very high	48 Å²	48	38.9 Å²	38.9	29%	0.291	20%	0.2	S	C	.	.	H	α-helix	trans	-67.4	-49.3	177.5	169.7	0	0	0	0	109.8	I117 S118 G119 D123 R124 I125 P130 F167	I117-V121 HydrophobicContact CG2-CG2 4.1Å; I117-V121 WeakPolarHBondContact O-CB 3.03Å; I117-V121 VanDerWaalsContact O-CG2 3.27Å; I117-V121 WeakPolarHBondContact O-CG2 3.49Å; I117-V121 PolarHBondContact O-N 3.32Å; S118-V121 PolarHBondContact O-N 3.09Å; G119-V121 PolarHBondContact O-N 2.86Å; V121-D123 VanDerWaalsContact C-N 3.35Å; V121-D123 PolarHBondContact O-N 3.32Å; V121-R124 PolarHBondContact O-N 2.89Å; V121-I125 HydrophobicContact CG1-CD1 3.7Å; V121-I125 HydrophobicContact CG1-CG1 3.86Å; V121-I125 WeakPolarHBondContact O-CG1 3.37Å; V121-I125 PolarHBondContact O-N 3.39Å; V121-P130 HydrophobicContact CG1-CG 4.23Å; V121-F167 HydrophobicContact CB-CE1 4.18Å; V121-F167 HydrophobicContact CG1-CE1 4.18Å
122	I	97	Very high	96.2	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-57.1	-46.8	-179.6	-70.6	161.2	0	0	0	111.3	S118 G119 R124 G126 Y127 P130 T170 A171	S118-I122 WeakPolarHBondContact O-CB 3.37Å; S118-I122 WeakPolarHBondContact O-CD1 3.15Å; S118-I122 WeakPolarHBondContact O-CG1 3.37Å; S118-I122 PolarHBondContact O-N 3.24Å; G119-I122 PolarHBondContact O-N 2.83Å; I122-R124 PolarHBondContact O-N 3.4Å; I122-G126 CarbonylContact O-C 3.54Å; I122-G126 WeakPolarHBondContact O-CA 3.47Å; I122-G126 PolarHBondContact O-N 3Å; I122-Y127 HydrophobicContact CG2-CD1 3.42Å; I122-Y127 VanDerWaalsContact CG2-CD1 3.42Å; I122-Y127 HydrophobicContact CG2-CE1 3.94Å; I122-Y127 HydrophobicContact CG2-CG 4.42Å; I122-P130 HydrophobicContact CB-CG 4.47Å; I122-P130 HydrophobicContact CD1-CB 4.5Å; I122-P130 HydrophobicContact CG1-CB 3.67Å; I122-P130 HydrophobicContact CG1-CG 3.72Å; I122-T170 HydrophobicContact CD1-CG2 3.47Å; I122-T170 VanDerWaalsContact CD1-CG2 3.47Å; I122-A171 HydrophobicContact CD1-CB 3.76Å; I122-A171 HydrophobicContact CG1-CB 4.17Å
123	D	95.8	Very high	96.2	Very high	13 Å²	13	42.7 Å²	42.7	7%	0.07	22%	0.216	C	C	.	.	H	α-helix	trans	-57.6	-38	178	-73.4	-4.8	0	0	0	112	G119 V121 R246 V395 G397 S398	G119-D123 VanDerWaalsContact O-CG 3.27Å; G119-D123 PolarHBondContact O-N 3.37Å; V121-D123 VanDerWaalsContact C-N 3.35Å; V121-D123 PolarHBondContact O-N 3.32Å; D123-R246 PolarHBondContact O-NH2 2.73Å; D123-V395 HydrophobicContact CB-CG1 3.91Å; D123-V395 WeakPolarHBondContact OD1-CG1 3.34Å; D123-G397 WeakPolarHBondContact OD1-CA 2.91Å; D123-G397 PolarHBondContact OD1-N 2.69Å; D123-S398 PolarHBondContact OD1-N 2.87Å; D123-S398 VanDerWaalsContact OD2-CB 3.23Å; D123-S398 WeakPolarHBondContact OD2-CB 3.4Å; D123-S398 PolarHBondContact OD2-N 3.26Å; D123-S398 PolarHBondContact OD2-OG 2.85Å
124	R	93.3	Very high	96.2	Very high	191 Å²	191	37.4 Å²	37.4	72%	0.721	19%	0.188	S	C	*	.	H	α-helix	trans	-80.1	-52.8	-176.8	-70.4	177.9	-178.6	-171.7	2.2	112.7	T120 V121 I122 R246	T120-R124 WeakPolarHBondContact O-CG 3.44Å; T120-R124 PolarHBondContact O-N 2.8Å; V121-R124 PolarHBondContact O-N 2.89Å; I122-R124 PolarHBondContact O-N 3.4Å; R124-R246 PolarHBondContact O-NH2 2.99Å
125	I	93.1	Very high	96.2	Very high	92 Å²	92	36.6 Å²	36.6	47%	0.472	18%	0.182	S	C	.	.	H	α-helix	trans	-94.5	-20	-168.9	70.1	168.6	0	0	0	114	V121 V129 P130	V121-I125 HydrophobicContact CG1-CD1 3.7Å; V121-I125 HydrophobicContact CG1-CG1 3.86Å; V121-I125 WeakPolarHBondContact O-CG1 3.37Å; V121-I125 PolarHBondContact O-N 3.39Å; I125-V129 HydrophobicContact CD1-CB 4.37Å; I125-V129 HydrophobicContact CD1-CG1 4.09Å; I125-P130 HydrophobicContact CD1-CG 3.74Å; I125-P130 HydrophobicContact CG1-CG 3.67Å
126	G	93.8	Very high	96.2	Very high	0 Å²	0	38.6 Å²	38.6	0%	0	20%	0.196	C	C	.	.			trans	115.8	175.4	-174.3	0	0	0	0	0	111.9	I122 P130 R246	I122-G126 CarbonylContact O-C 3.54Å; I122-G126 WeakPolarHBondContact O-CA 3.47Å; I122-G126 PolarHBondContact O-N 3Å; G126-P130 WeakPolarHBondContact O-CD 3.35Å; G126-P130 WeakPolarHBondContact O-CG 3.4Å; G126-R246 VanDerWaalsContact N-CZ 3.34Å; G126-R246 VanDerWaalsContact N-NH2 3.16Å
127	Y	94.2	Very high	96.3	Very high	10 Å²	10	37 Å²	37	4%	0.039	18%	0.184	C	C	.	.	S	Bend	trans	-86.7	-40.9	-171.8	-49.1	-70.6	0	0	0	112.5	I122 P130 M131 A171 A174 M175 D178	I122-Y127 HydrophobicContact CG2-CD1 3.42Å; I122-Y127 VanDerWaalsContact CG2-CD1 3.42Å; I122-Y127 HydrophobicContact CG2-CE1 3.94Å; I122-Y127 HydrophobicContact CG2-CG 4.42Å; Y127-P130 WeakPolarHBondContact O-CD 3.49Å; Y127-M131 WeakPolarHBondContact O-CB 3.46Å; Y127-M131 PolarHBondContact O-N 3.44Å; Y127-M131 VanDerWaalsContact O-N 3.13Å; Y127-A171 VanDerWaalsContact O-CB 3.29Å; Y127-A171 WeakPolarHBondContact O-CB 3.44Å; Y127-A174 HydrophobicContact CD1-CB 3.69Å; Y127-A174 HydrophobicContact CE1-CB 3.76Å; Y127-M175 HydrophobicContact CG-CB 4.37Å; Y127-D178 HydrophobicContact CD2-CB 4.42Å; Y127-D178 HydrophobicContact CE2-CB 3.67Å; Y127-D178 VanDerWaalsContact CE2-OD1 3.26Å; Y127-D178 WeakPolarHBondContact CE2-OD1 3.37Å; Y127-D178 PolarHBondContact OH-OD1 3.39Å
128	D	93.9	Very high	96.3	Very high	7 Å²	7	32.2 Å²	32.2	4%	0.037	16%	0.16	C	C	.	.	H	α-helix	trans	-80.5	-36.2	-165.8	63.8	-32.3	0	0	0	114.7	M131 M132 M175 L235 M239 R243	D128-M131 PolarHBondContact O-N 3.22Å; D128-M132 WeakPolarHBondContact O-CB 3.12Å; D128-M132 PolarHBondContact O-N 3.05Å; D128-M175 HydrophobicContact CB-CE 4.04Å; D128-L235 HydrophobicContact CB-CD2 4.31Å; D128-L235 HydrophobicContact CB-CG 4.38Å; D128-M239 HydrophobicContact CB-CB 3.73Å; D128-M239 HydrophobicContact CB-CE 3.99Å; D128-M239 HydrophobicContact CB-CG 3.7Å; D128-M239 WeakPolarHBondContact OD2-CB 3.42Å; D128-R243 IonicContact OD2-CZ 3.11Å; D128-R243 IonicContact OD2-NE 2.58Å; D128-R243 PolarHBondContact OD2-NE 3.27Å; D128-R243 IonicContact OD2-NH2 2.8Å; D128-R243 PolarHBondContact OD2-NH2 3.37Å
129	V	95.5	Very high	96.3	Very high	71 Å²	71	34.2 Å²	34.2	43%	0.43	17%	0.168	S	C	.	.	H	α-helix	trans	-63.8	-48.6	174.1	175.7	0	0	0	0	111.9	I125 M131 M132 F133	I125-V129 HydrophobicContact CD1-CB 4.37Å; I125-V129 HydrophobicContact CD1-CG1 4.09Å; V129-M131 PolarHBondContact O-N 3Å; V129-M132 PolarHBondContact O-N 3.47Å; V129-F133 PolarHBondContact O-N 2.92Å
130	P	96.9	Very high	96.3	Very high	3 Å²	3	39.2 Å²	39.2	2%	0.019	20%	0.195	C	C	.	.	H	α-helix	trans	-60.5	-40.2	171.9	-19.6	27.3	0	0	0	113.7	V121 I122 I125 G126 Y127 M132 F133 G134 F167	V121-P130 HydrophobicContact CG1-CG 4.23Å; I122-P130 HydrophobicContact CB-CG 4.47Å; I122-P130 HydrophobicContact CD1-CB 4.5Å; I122-P130 HydrophobicContact CG1-CB 3.67Å; I122-P130 HydrophobicContact CG1-CG 3.72Å; I125-P130 HydrophobicContact CD1-CG 3.74Å; I125-P130 HydrophobicContact CG1-CG 3.67Å; G126-P130 WeakPolarHBondContact O-CD 3.35Å; G126-P130 WeakPolarHBondContact O-CG 3.4Å; Y127-P130 WeakPolarHBondContact O-CD 3.49Å; P130-M132 PolarHBondContact O-N 3.47Å; P130-F133 WeakPolarHBondContact O-CB 3.16Å; P130-F133 PolarHBondContact O-N 3.36Å; P130-G134 PolarHBondContact O-N 3.4Å; P130-F167 HydrophobicContact CB-CD1 3.9Å
131	M	97.3	Very high	96.4	Very high	0 Å²	0	37.1 Å²	37.1	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-61.5	-45	177.7	-173.8	175	170.8	0	0	111.3	V28 V29 A32 Y127 D128 V129 F133 G134 L135 A171 M175 L235	V28-M131 HydrophobicContact CG1-CE 4.12Å; V29-M131 HydrophobicContact CG2-CE 4.12Å; V29-M131 HydrophobicContact CG2-SD 4.31Å; A32-M131 HydrophobicContact CB-CE 3.52Å; Y127-M131 WeakPolarHBondContact O-CB 3.46Å; Y127-M131 PolarHBondContact O-N 3.44Å; Y127-M131 VanDerWaalsContact O-N 3.13Å; D128-M131 PolarHBondContact O-N 3.22Å; V129-M131 PolarHBondContact O-N 3Å; M131-F133 VanDerWaalsContact C-N 3.32Å; M131-F133 PolarHBondContact O-N 2.89Å; M131-G134 PolarHBondContact O-N 3.2Å; M131-L135 HydrophobicContact CE-CD1 4.24Å; M131-L135 HydrophobicContact CG-CD1 4.26Å; M131-L135 WeakPolarHBondContact O-CG 3.26Å; M131-L135 PolarHBondContact O-N 2.87Å; M131-A171 HydrophobicContact CB-CB 3.71Å; M131-A171 HydrophobicContact CG-CB 4.41Å; M131-M175 HydrophobicContact CB-CE 4.48Å; M131-M175 HydrophobicContact SD-CE 3.66Å; M131-L235 HydrophobicContact CB-CD2 3.65Å; M131-L235 HydrophobicContact CE-CD2 4.19Å; M131-L235 HydrophobicContact CG-CD2 3.56Å; M131-L235 HydrophobicContact SD-CD1 3.96Å; M131-L235 HydrophobicContact SD-CD2 3.45Å; M131-L235 WeakPolarHBondContact SD-CD2 3.11Å; M131-L235 HydrophobicContact SD-CG 4.33Å
132	M	97	Very high	96.3	Very high	28 Å²	28	34.8 Å²	34.8	14%	0.138	17%	0.168	C	C	.	.	H	α-helix	trans	-60.2	-42.5	173.7	-179.8	66.7	-166.4	0	0	111.8	D128 V129 P130 G134 L135 C136 L229 G232 L236	D128-M132 WeakPolarHBondContact O-CB 3.12Å; D128-M132 PolarHBondContact O-N 3.05Å; V129-M132 PolarHBondContact O-N 3.47Å; P130-M132 PolarHBondContact O-N 3.47Å; M132-G134 VanDerWaalsContact C-N 3.33Å; M132-G134 PolarHBondContact O-N 3.32Å; M132-L135 PolarHBondContact O-N 3.42Å; M132-C136 WeakPolarHBondContact CE-SG 3.12Å; M132-C136 WeakPolarHBondContact O-CB 3.28Å; M132-C136 PolarHBondContact O-N 2.91Å; M132-C136 PolarHBondContact O-SG 2.94Å; M132-C136 VanDerWaalsContact O-SG 3.39Å; M132-L229 HydrophobicContact CE-CD1 4.37Å; M132-G232 WeakPolarHBondContact SD-CA 3.1Å; M132-G232 VanDerWaalsContact SD-O 3.34Å; M132-L236 HydrophobicContact CB-CD2 4.01Å; M132-L236 HydrophobicContact CB-CG 4.32Å; M132-L236 HydrophobicContact CE-CD1 4.29Å; M132-L236 HydrophobicContact CG-CD1 3.92Å; M132-L236 HydrophobicContact CG-CD2 4.09Å; M132-L236 HydrophobicContact CG-CG 4.02Å; M132-L236 HydrophobicContact SD-CD1 3.92Å; M132-L236 HydrophobicContact SD-CG 3.99Å
133	F	97.4	Very high	96.3	Very high	103 Å²	103	35.9 Å²	35.9	45%	0.452	18%	0.175	S	C	.	.	H	α-helix	trans	-59	-45.1	175.1	172.4	-101.9	0	0	0	111.6	V129 P130 M131 C136 I137 F167	V129-F133 PolarHBondContact O-N 2.92Å; P130-F133 WeakPolarHBondContact O-CB 3.16Å; P130-F133 PolarHBondContact O-N 3.36Å; M131-F133 VanDerWaalsContact C-N 3.32Å; M131-F133 PolarHBondContact O-N 2.89Å; F133-C136 WeakPolarHBondContact O-CB 3.34Å; F133-C136 PolarHBondContact O-N 2.92Å; F133-I137 HydrophobicContact CD1-CD1 3.75Å; F133-I137 HydrophobicContact CD2-CD1 4.4Å; F133-I137 HydrophobicContact CE1-CD1 3.25Å; F133-I137 HydrophobicContact CE1-CG1 4.47Å; F133-I137 HydrophobicContact CE2-CD1 3.98Å; F133-I137 HydrophobicContact CE2-CG1 4.49Å; F133-I137 HydrophobicContact CG-CD1 4.31Å; F133-I137 HydrophobicContact CZ-CD1 3.39Å; F133-I137 HydrophobicContact CZ-CG1 4.33Å; F133-I137 WeakPolarHBondContact O-CG1 3.26Å; F133-I137 PolarHBondContact O-N 3.02Å; F133-F167 HydrophobicContact CD1-CD1 4.3Å; F133-F167 AromaticContact CD1-CD2 3.97Å; F133-F167 HydrophobicContact CD1-CD2 3.97Å; F133-F167 HydrophobicContact CD1-CE1 4.48Å; F133-F167 HydrophobicContact CD1-CE2 4.21Å; F133-F167 HydrophobicContact CD1-CG 4.03Å; F133-F167 HydrophobicContact CD1-CZ 4.45Å; F133-F167 AromaticContact CE1-CD2 3.88Å; F133-F167 HydrophobicContact CE1-CD2 3.88Å; F133-F167 AromaticContact CE1-CE2 3.77Å; F133-F167 HydrophobicContact CE1-CE2 3.77Å; F133-F167 HydrophobicContact CE1-CG 4.39Å; F133-F167 HydrophobicContact CE1-CZ 4.14Å
134	G	97.9	Very high	96.2	Very high	0 Å²	0	38.1 Å²	38.1	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-58.4	-50	173.8	0	0	0	0	0	112.5	P130 M131 M132 C136 I137 I138 G164	P130-G134 PolarHBondContact O-N 3.4Å; M131-G134 PolarHBondContact O-N 3.2Å; M132-G134 VanDerWaalsContact C-N 3.33Å; M132-G134 PolarHBondContact O-N 3.32Å; G134-C136 VanDerWaalsContact C-N 3.35Å; G134-C136 PolarHBondContact O-N 3.03Å; G134-I137 WeakPolarHBondContact O-CB 3.37Å; G134-I137 PolarHBondContact O-N 3.18Å; G134-I137 VanDerWaalsContact O-N 3.11Å; G134-I138 WeakPolarHBondContact O-CG1 3.37Å; G134-I138 PolarHBondContact O-N 2.89Å; G134-G164 WeakPolarHBondContact CA-O 3.44Å
135	L	97.7	Very high	96.1	Very high	3 Å²	3	29.1 Å²	29.1	2%	0.016	16%	0.155	C	C	.	.	H	α-helix	trans	-63.2	-36.4	178.4	-69.7	172	0	0	0	112.9	A32 M131 M132 I138 F139 A168 A228 G232	A32-L135 HydrophobicContact CB-CD2 4.2Å; M131-L135 HydrophobicContact CE-CD1 4.24Å; M131-L135 HydrophobicContact CG-CD1 4.26Å; M131-L135 WeakPolarHBondContact O-CG 3.26Å; M131-L135 PolarHBondContact O-N 2.87Å; M132-L135 PolarHBondContact O-N 3.42Å; L135-I138 HydrophobicContact CD2-CD1 4.48Å; L135-I138 PolarHBondContact O-N 3.14Å; L135-F139 WeakPolarHBondContact O-CB 3.41Å; L135-F139 PolarHBondContact O-N 2.95Å; L135-A168 HydrophobicContact CD2-CB 4.38Å; L135-A168 HydrophobicContact CG-CB 4.41Å; L135-A228 HydrophobicContact CD2-CB 4.28Å; L135-G232 VanDerWaalsContact CD1-CA 3.49Å
136	C	98	Very high	96.1	Very high	42 Å²	42	24.7 Å²	24.7	28%	0.284	13%	0.133	S	C	.	.	H	α-helix	trans	-62.4	-43.3	171.2	-79.5	0	0	0	0	112.1	M132 F133 G134 I138 F139 L140	M132-C136 WeakPolarHBondContact CE-SG 3.12Å; M132-C136 WeakPolarHBondContact O-CB 3.28Å; M132-C136 PolarHBondContact O-N 2.91Å; M132-C136 PolarHBondContact O-SG 2.94Å; M132-C136 VanDerWaalsContact O-SG 3.39Å; F133-C136 WeakPolarHBondContact O-CB 3.34Å; F133-C136 PolarHBondContact O-N 2.92Å; G134-C136 VanDerWaalsContact C-N 3.35Å; G134-C136 PolarHBondContact O-N 3.03Å; C136-I138 VanDerWaalsContact C-N 3.34Å; C136-F139 PolarHBondContact O-N 3.33Å; C136-L140 WeakPolarHBondContact O-CG 3.03Å; C136-L140 PolarHBondContact O-N 3.05Å
137	I	97.8	Very high	96	Very high	17 Å²	17	31.1 Å²	31.1	9%	0.087	16%	0.161	C	C	.	.	H	α-helix	trans	-63.5	-43.4	174.8	-68.4	162.7	0	0	0	110	F133 G134 F139 L140 S141 L160 M163	F133-I137 HydrophobicContact CD1-CD1 3.75Å; F133-I137 HydrophobicContact CD2-CD1 4.4Å; F133-I137 HydrophobicContact CE1-CD1 3.25Å; F133-I137 HydrophobicContact CE1-CG1 4.47Å; F133-I137 HydrophobicContact CE2-CD1 3.98Å; F133-I137 HydrophobicContact CE2-CG1 4.49Å; F133-I137 HydrophobicContact CG-CD1 4.31Å; F133-I137 HydrophobicContact CZ-CD1 3.39Å; F133-I137 HydrophobicContact CZ-CG1 4.33Å; F133-I137 WeakPolarHBondContact O-CG1 3.26Å; F133-I137 PolarHBondContact O-N 3.02Å; G134-I137 WeakPolarHBondContact O-CB 3.37Å; G134-I137 PolarHBondContact O-N 3.18Å; G134-I137 VanDerWaalsContact O-N 3.11Å; I137-F139 PolarHBondContact O-N 3.34Å; I137-L140 PolarHBondContact O-N 2.83Å; I137-S141 WeakPolarHBondContact O-CB 3.21Å; I137-S141 PolarHBondContact O-N 3.33Å; I137-S141 PolarHBondContact O-OG 3.18Å; I137-L160 HydrophobicContact CG2-CB 4.2Å; I137-L160 WeakPolarHBondContact CG2-O 3.37Å; I137-M163 HydrophobicContact CD1-CE 3.83Å; I137-M163 HydrophobicContact CD1-CG 4.21Å; I137-M163 HydrophobicContact CD1-SD 4.39Å; I137-M163 HydrophobicContact CG1-CE 4.38Å; I137-M163 HydrophobicContact CG2-CE 4.01Å
138	I	97.4	Very high	95.6	Very high	4 Å²	4	30.7 Å²	30.7	2%	0.021	16%	0.16	C	C	.	.	H	α-helix	trans	-59.6	-45.8	175.9	-68.7	175	0	0	0	110.5	L39 G134 L135 C136 S141 T142 A168 A228	L39-I138 HydrophobicContact CD1-CG2 3.37Å; G134-I138 WeakPolarHBondContact O-CG1 3.37Å; G134-I138 PolarHBondContact O-N 2.89Å; L135-I138 HydrophobicContact CD2-CD1 4.48Å; L135-I138 PolarHBondContact O-N 3.14Å; C136-I138 VanDerWaalsContact C-N 3.34Å; I138-S141 WeakPolarHBondContact CA-OG 3.01Å; I138-S141 PolarHBondContact O-OG 3.25Å; I138-S141 VanDerWaalsContact O-OG 3.08Å; I138-T142 WeakPolarHBondContact O-CB 3.5Å; I138-T142 PolarHBondContact O-N 3.02Å; I138-T142 PolarHBondContact O-OG1 3.28Å; I138-A168 HydrophobicContact CD1-CB 4.25Å; I138-A228 HydrophobicContact CG2-CB 4.06Å
139	F	97.9	Very high	95	Very high	42 Å²	42	34.1 Å²	34.1	18%	0.184	18%	0.184	C	C	.	.	H	α-helix	trans	-57.2	-51.9	175.3	165.1	-104.1	0	0	0	111.9	L135 C136 I137 S143 A225 F226 L229	L135-F139 WeakPolarHBondContact O-CB 3.41Å; L135-F139 PolarHBondContact O-N 2.95Å; C136-F139 PolarHBondContact O-N 3.33Å; I137-F139 PolarHBondContact O-N 3.34Å; F139-S143 WeakPolarHBondContact O-CB 3.44Å; F139-S143 PolarHBondContact O-N 3.31Å; F139-S143 PolarHBondContact O-OG 3.5Å; F139-A225 HydrophobicContact CD2-CB 3.78Å; F139-A225 WeakPolarHBondContact CD2-O 3.28Å; F139-A225 HydrophobicContact CE2-CB 4.33Å; F139-F226 HydrophobicContact CE2-CD1 4.43Å; F139-F226 HydrophobicContact CE2-CE1 4.33Å; F139-F226 HydrophobicContact CE2-CZ 4.39Å; F139-L229 HydrophobicContact CB-CB 4.38Å; F139-L229 HydrophobicContact CD2-CB 3.94Å; F139-L229 HydrophobicContact CD2-CD2 4.2Å; F139-L229 HydrophobicContact CE1-CD2 4.39Å; F139-L229 HydrophobicContact CE2-CB 4.5Å; F139-L229 HydrophobicContact CE2-CD2 4.01Å; F139-L229 HydrophobicContact CG-CB 4.16Å; F139-L229 HydrophobicContact CG-CD2 4.48Å; F139-L229 HydrophobicContact CZ-CD2 4.11Å
140	L	97.7	Very high	94.6	Very high	105 Å²	105	33.2 Å²	33.2	55%	0.55	18%	0.181	S	C	.	.	H	α-helix	trans	-65	-48	-178.3	-70.5	172.2	0	0	0	111.5	C136 I137 S143 V144	C136-L140 WeakPolarHBondContact O-CG 3.03Å; C136-L140 PolarHBondContact O-N 3.05Å; I137-L140 PolarHBondContact O-N 2.83Å; L140-S143 WeakPolarHBondContact O-CB 3.29Å; L140-S143 PolarHBondContact O-N 3.49Å; L140-V144 VanDerWaalsContact O-CG2 3.31Å; L140-V144 WeakPolarHBondContact O-CG2 3.12Å; L140-V144 PolarHBondContact O-N 3Å
141	S	97.4	Very high	94	Very high	0 Å²	0	35.7 Å²	35.7	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-65.7	-40.7	-178.5	59.8	0	0	0	0	112.4	I137 I138 S143 V144 F145 A157 L160 Q161	I137-S141 WeakPolarHBondContact O-CB 3.21Å; I137-S141 PolarHBondContact O-N 3.33Å; I137-S141 PolarHBondContact O-OG 3.18Å; I138-S141 WeakPolarHBondContact CA-OG 3.01Å; I138-S141 PolarHBondContact O-OG 3.25Å; I138-S141 VanDerWaalsContact O-OG 3.08Å; S141-S143 VanDerWaalsContact C-N 3.34Å; S141-V144 PolarHBondContact O-N 2.91Å; S141-F145 WeakPolarHBondContact O-CB 3.29Å; S141-F145 PolarHBondContact O-N 3.39Å; S141-A157 WeakPolarHBondContact CB-O 3.24Å; S141-A157 WeakPolarHBondContact O-CB 3.23Å; S141-L160 VanDerWaalsContact CB-CB 3.49Å; S141-Q161 WeakPolarHBondContact OG-CG 3.32Å
142	T	96	Very high	93.6	Very high	0 Å²	0	37.7 Å²	37.7	0%	0	21%	0.21	C	C	.	.	H	α-helix	trans	-66.3	-37.6	174.1	-56.7	0	0	0	0	111.4	L39 I138 F145 A146 Q161 F221 A225	L39-T142 HydrophobicContact CD2-CG2 3.5Å; L39-T142 VanDerWaalsContact CD2-CG2 3.5Å; I138-T142 WeakPolarHBondContact O-CB 3.5Å; I138-T142 PolarHBondContact O-N 3.02Å; I138-T142 PolarHBondContact O-OG1 3.28Å; T142-F145 WeakPolarHBondContact O-CB 3.15Å; T142-F145 PolarHBondContact O-N 3.39Å; T142-A146 WeakPolarHBondContact O-CB 3.36Å; T142-A146 PolarHBondContact O-N 3.46Å; T142-Q161 PolarHBondContact OG1-NE2 2.93Å; T142-F221 HydrophobicContact CG2-CB 3.83Å; T142-F221 HydrophobicContact CG2-CD1 4.1Å; T142-F221 HydrophobicContact CG2-CG 4.44Å; T142-F221 WeakPolarHBondContact CG2-O 3.34Å; T142-A225 HydrophobicContact CG2-CB 3.9Å
143	S	96	Very high	93.3	Very high	22 Å²	22	39.9 Å²	39.9	15%	0.154	22%	0.223	C	C	.	.	H	α-helix	trans	-64	-43.6	172.5	-56.4	0	0	0	0	111.7	F139 L140 S141 F145 A146 F147	F139-S143 WeakPolarHBondContact O-CB 3.44Å; F139-S143 PolarHBondContact O-N 3.31Å; F139-S143 PolarHBondContact O-OG 3.5Å; L140-S143 WeakPolarHBondContact O-CB 3.29Å; L140-S143 PolarHBondContact O-N 3.49Å; S141-S143 VanDerWaalsContact C-N 3.34Å; S143-F145 VanDerWaalsContact C-N 3.27Å; S143-F145 PolarHBondContact O-N 3.5Å; S143-A146 WeakPolarHBondContact O-CB 3.08Å; S143-A146 PolarHBondContact O-N 3.37Å; S143-A146 VanDerWaalsContact O-N 3.17Å; S143-F147 WeakPolarHBondContact O-CD2 3.5Å; S143-F147 PolarHBondContact O-N 2.87Å
144	V	94.6	Very high	93	Very high	61 Å²	61	35 Å²	35	37%	0.37	20%	0.201	S	C	.	.	H	α-helix	trans	-61.2	-38.6	174	172.7	0	0	0	0	110.8	L140 S141 G148 A157	L140-V144 VanDerWaalsContact O-CG2 3.31Å; L140-V144 WeakPolarHBondContact O-CG2 3.12Å; L140-V144 PolarHBondContact O-N 3Å; S141-V144 PolarHBondContact O-N 2.91Å; V144-G148 VanDerWaalsContact O-CA 3.31Å; V144-G148 WeakPolarHBondContact O-CA 3.31Å; V144-G148 PolarHBondContact O-N 3.39Å; V144-A157 HydrophobicContact CB-CB 4.36Å; V144-A157 HydrophobicContact CG1-CB 4.08Å
145	F	91.6	Very high	92.7	Very high	1 Å²	1	38 Å²	38	0%	0.004	21%	0.214	C	C	.	.	H	α-helix	trans	-64.8	-42.1	175.3	-160.3	-83.7	0	0	0	111.5	I43 I47 S141 T142 S143 F147 G148 M154 A157 R158 F221	I43-F145 HydrophobicContact CG2-CE1 4.27Å; I43-F145 HydrophobicContact CG2-CZ 4.24Å; I47-F145 HydrophobicContact CD1-CE1 3.7Å; I47-F145 HydrophobicContact CD1-CZ 3.46Å; I47-F145 VanDerWaalsContact CD1-CZ 3.46Å; I47-F145 HydrophobicContact CG1-CE1 4.4Å; I47-F145 HydrophobicContact CG1-CZ 4.05Å; S141-F145 WeakPolarHBondContact O-CB 3.29Å; S141-F145 PolarHBondContact O-N 3.39Å; T142-F145 WeakPolarHBondContact O-CB 3.15Å; T142-F145 PolarHBondContact O-N 3.39Å; S143-F145 VanDerWaalsContact C-N 3.27Å; S143-F145 PolarHBondContact O-N 3.5Å; F145-F147 PolarHBondContact O-N 2.81Å; F145-G148 PolarHBondContact O-N 3.12Å; F145-M154 HydrophobicContact CD2-CB 4.16Å; F145-M154 HydrophobicContact CD2-CG 4.3Å; F145-M154 HydrophobicContact CE2-CB 3.76Å; F145-M154 HydrophobicContact CE2-CG 4.05Å; F145-M154 HydrophobicContact CZ-CB 4.37Å; F145-M154 HydrophobicContact CZ-CG 4.31Å; F145-M154 HydrophobicContact CZ-SD 4.37Å; F145-A157 HydrophobicContact CB-CB 4Å; F145-A157 HydrophobicContact CD2-CB 3.92Å; F145-A157 HydrophobicContact CG-CB 4.47Å; F145-R158 HydrophobicContact CD2-CG 4.42Å; F145-R158 HydrophobicContact CE2-CG 3.98Å; F145-F221 AromaticContact CD1-CD1 3.91Å; F145-F221 HydrophobicContact CD1-CD1 3.91Å; F145-F221 AromaticContact CD1-CD2 3.8Å; F145-F221 HydrophobicContact CD1-CD2 3.8Å; F145-F221 AromaticContact CD1-CE1 3.66Å; F145-F221 HydrophobicContact CD1-CE1 3.66Å; F145-F221 AromaticContact CD1-CE2 3.6Å; F145-F221 HydrophobicContact CD1-CE2 3.6Å; F145-F221 HydrophobicContact CD1-CG 4Å; F145-F221 AromaticContact CD1-CZ 3.54Å; F145-F221 HydrophobicContact CD1-CZ 3.54Å; F145-F221 HydrophobicContact CE1-CD1 4.46Å; F145-F221 HydrophobicContact CE1-CD2 4.24Å; F145-F221 AromaticContact CE1-CE1 3.77Å; F145-F221 HydrophobicContact CE1-CE1 3.77Å; F145-F221 AromaticContact CE1-CE2 3.55Å; F145-F221 HydrophobicContact CE1-CE2 3.55Å; F145-F221 AromaticContact CE1-CZ 3.29Å; F145-F221 HydrophobicContact CE1-CZ 3.29Å; F145-F221 HydrophobicContact CZ-CZ 4.39Å
146	A	92.6	Very high	92.5	Very high	0 Å²	0	42.6 Å²	42.6	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-60.2	-43.5	178.2	0	0	0	0	0	112.1	T142 S143 K217 F221 I222	T142-A146 WeakPolarHBondContact O-CB 3.36Å; T142-A146 PolarHBondContact O-N 3.46Å; S143-A146 WeakPolarHBondContact O-CB 3.08Å; S143-A146 PolarHBondContact O-N 3.37Å; S143-A146 VanDerWaalsContact O-N 3.17Å; A146-K217 PolarHBondContact O-NZ 3.34Å; A146-F221 HydrophobicContact CB-CB 3.65Å; A146-I222 HydrophobicContact CB-CG1 3.87Å
147	F	91.9	Very high	92.4	Very high	134 Å²	134	40.6 Å²	40.6	59%	0.588	22%	0.224	S	C	*	.	H	α-helix	trans	-94.6	-6	-178.8	-60.6	-65	0	0	0	114.1	S143 F145 S149 E218 I222	S143-F147 WeakPolarHBondContact O-CD2 3.5Å; S143-F147 PolarHBondContact O-N 2.87Å; F145-F147 PolarHBondContact O-N 2.81Å; F147-S149 PolarHBondContact O-N 2.89Å; F147-E218 HydrophobicContact CD1-CG 4.41Å; F147-E218 HydrophobicContact CE1-CG 4.41Å; F147-I222 HydrophobicContact CE1-CD1 4.02Å; F147-I222 HydrophobicContact CE2-CD1 4.22Å; F147-I222 HydrophobicContact CE2-CG1 4.43Å; F147-I222 HydrophobicContact CZ-CD1 3.52Å; F147-I222 HydrophobicContact CZ-CG1 4.2Å
148	G	85.3	Confident	92.2	Very high	2 Å²	2	39.8 Å²	39.8	2%	0.021	22%	0.22	C	C	.	.			trans	-63.4	121.4	-178.5	0	0	0	0	0	112.3	Y50 V144 F145 M154	Y50-G148 PolarHBondContact OH-O 2.77Å; V144-G148 VanDerWaalsContact O-CA 3.31Å; V144-G148 WeakPolarHBondContact O-CA 3.31Å; V144-G148 PolarHBondContact O-N 3.39Å; F145-G148 PolarHBondContact O-N 3.12Å; G148-M154 WeakPolarHBondContact O-CE 3.33Å
149	S	82	Confident	92.2	Very high	79 Å²	79	39.9 Å²	39.9	55%	0.552	22%	0.222	S	C	*	.			trans	-94.9	-15.3	177.4	56	0	0	0	0	113.4	L54 F147	L54-S149 WeakPolarHBondContact CD1-O 3.48Å; F147-S149 PolarHBondContact O-N 2.89Å
150	S	86.1	Confident	92.2	Very high	51 Å²	51	41 Å²	41	36%	0.357	23%	0.229	S	C	.	.	S	Bend	trans	-117.5	151	-177.1	78.4	0	0	0	0	112.5	G152 L153 M154	S150-G152 PolarHBondContact O-N 3.45Å; S150-L153 PolarHBondContact O-N 3.25Å; S150-L153 WeakPolarHBondContact OG-CG 3.39Å; S150-L153 PolarHBondContact OG-N 3.01Å; S150-M154 PolarHBondContact O-N 3.48Å; S150-M154 VanDerWaalsContact O-N 3.14Å
151	Y	85.5	Confident	92.1	Very high	56 Å²	56	36.1 Å²	36.1	22%	0.22	20%	0.204	C	C	.	.	H	α-helix	trans	-58.1	-36.7	173.7	-179.1	-102.3	0	0	0	112.1	L51 K99 L103 M154 F155	L51-Y151 HydrophobicContact CD1-CD2 4.5Å; L51-Y151 HydrophobicContact CD2-CD2 4.21Å; K99-Y151 HydrophobicContact CB-CE2 3.69Å; K99-Y151 HydrophobicContact CD-CD2 4.12Å; K99-Y151 HydrophobicContact CD-CE2 4Å; K99-Y151 HydrophobicContact CG-CE2 3.92Å; K99-Y151 PolarHBondContact O-OH 3.44Å; K99-Y151 VanDerWaalsContact O-OH 3.14Å; L103-Y151 HydrophobicContact CD1-CE2 4.07Å; L103-Y151 HydrophobicContact CD2-CE2 4.16Å; L103-Y151 HydrophobicContact CG-CE2 3.99Å; Y151-M154 PolarHBondContact O-N 2.83Å; Y151-F155 VanDerWaalsContact O-CB 3.32Å; Y151-F155 WeakPolarHBondContact O-CB 3.4Å; Y151-F155 PolarHBondContact O-N 2.95Å
152	G	88.2	Confident	92.2	Very high	41 Å²	41	36.1 Å²	36.1	42%	0.423	20%	0.204	S	C	.	.	H	α-helix	trans	-63.4	-41.5	177.8	0	0	0	0	0	113.2	S150 F155 I156	S150-G152 PolarHBondContact O-N 3.45Å; G152-F155 PolarHBondContact O-N 2.86Å; G152-I156 WeakPolarHBondContact O-CG1 3.42Å; G152-I156 PolarHBondContact O-N 3.31Å
153	L	91.1	Very high	92.3	Very high	75 Å²	75	38.5 Å²	38.5	39%	0.393	22%	0.216	S	C	.	.	H	α-helix	trans	-66.1	-41.8	175.1	-74.3	170.5	0	0	0	111.7	S150 F155 I156 A157	S150-L153 PolarHBondContact O-N 3.25Å; S150-L153 WeakPolarHBondContact OG-CG 3.39Å; S150-L153 PolarHBondContact OG-N 3.01Å; L153-F155 VanDerWaalsContact C-N 3.31Å; L153-F155 PolarHBondContact O-N 3.47Å; L153-I156 PolarHBondContact O-N 3.26Å; L153-A157 WeakPolarHBondContact O-CB 3.21Å; L153-A157 PolarHBondContact O-N 3.02Å
154	M	90	Very high	92.4	Very high	1 Å²	1	37.4 Å²	37.4	1%	0.005	21%	0.208	C	C	.	.	H	α-helix	trans	-62.6	-38.9	175.1	-69.5	-178.6	172.9	0	0	112.2	I47 Y50 L103 F145 G148 S150 Y151 A157 R158 K217	I47-M154 HydrophobicContact CD1-CE 4.34Å; I47-M154 HydrophobicContact CD1-SD 3.85Å; Y50-M154 HydrophobicContact CD1-CE 3.56Å; Y50-M154 HydrophobicContact CD1-SD 4.35Å; Y50-M154 HydrophobicContact CE1-CE 3.2Å; Y50-M154 HydrophobicContact CE1-SD 4.29Å; L103-M154 HydrophobicContact CD2-CB 4.49Å; F145-M154 HydrophobicContact CD2-CB 4.16Å; F145-M154 HydrophobicContact CD2-CG 4.3Å; F145-M154 HydrophobicContact CE2-CB 3.76Å; F145-M154 HydrophobicContact CE2-CG 4.05Å; F145-M154 HydrophobicContact CZ-CB 4.37Å; F145-M154 HydrophobicContact CZ-CG 4.31Å; F145-M154 HydrophobicContact CZ-SD 4.37Å; G148-M154 WeakPolarHBondContact O-CE 3.33Å; S150-M154 PolarHBondContact O-N 3.48Å; S150-M154 VanDerWaalsContact O-N 3.14Å; Y151-M154 PolarHBondContact O-N 2.83Å; M154-A157 PolarHBondContact O-N 2.91Å; M154-R158 WeakPolarHBondContact O-CG 3.45Å; M154-R158 PolarHBondContact O-N 3.49Å; M154-K217 HydrophobicContact CE-CD 4.5Å
155	F	91.3	Very high	92.5	Very high	61 Å²	61	34.5 Å²	34.5	27%	0.268	19%	0.191	S	C	.	.	H	α-helix	trans	-63.1	-49.4	176.2	-177.5	-98.5	0	0	0	111.5	T102 L103 F106 Y151 G152 L153 A157 R158 G159	T102-F155 HydrophobicContact CG2-CD2 4.32Å; T102-F155 HydrophobicContact CG2-CE2 3.85Å; L103-F155 HydrophobicContact CD2-CB 4.17Å; L103-F155 HydrophobicContact CD2-CD2 4.27Å; F106-F155 HydrophobicContact CB-CD2 4.26Å; F106-F155 HydrophobicContact CB-CE2 3.58Å; F106-F155 HydrophobicContact CB-CZ 4.03Å; F106-F155 HydrophobicContact CD1-CD1 4.03Å; F106-F155 AromaticContact CD1-CD2 3.89Å; F106-F155 HydrophobicContact CD1-CD2 3.89Å; F106-F155 AromaticContact CD1-CE1 3.75Å; F106-F155 HydrophobicContact CD1-CE1 3.75Å; F106-F155 AromaticContact CD1-CE2 3.6Å; F106-F155 HydrophobicContact CD1-CE2 3.6Å; F106-F155 HydrophobicContact CD1-CG 4.1Å; F106-F155 AromaticContact CD1-CZ 3.53Å; F106-F155 HydrophobicContact CD1-CZ 3.53Å; F106-F155 VanDerWaalsContact CD1-O 3.23Å; F106-F155 WeakPolarHBondContact CD1-O 3.26Å; F106-F155 HydrophobicContact CD2-CE1 4.07Å; F106-F155 AromaticContact CD2-CE2 3.9Å; F106-F155 HydrophobicContact CD2-CE2 3.9Å; F106-F155 AromaticContact CD2-CZ 3.39Å; F106-F155 HydrophobicContact CD2-CZ 3.39Å; F106-F155 AromaticContact CE1-CD1 3.8Å; F106-F155 HydrophobicContact CE1-CD1 3.8Å; F106-F155 HydrophobicContact CE1-CD2 4.49Å; F106-F155 AromaticContact CE1-CE1 3.48Å; F106-F155 HydrophobicContact CE1-CE1 3.48Å; F106-F155 VanDerWaalsContact CE1-CE1 3.48Å; F106-F155 HydrophobicContact CE1-CE2 4.23Å; F106-F155 HydrophobicContact CE1-CG 4.3Å; F106-F155 AromaticContact CE1-CZ 3.73Å; F106-F155 HydrophobicContact CE1-CZ 3.73Å; F106-F155 VanDerWaalsContact CE1-O 3.26Å; F106-F155 WeakPolarHBondContact CE1-O 3.41Å; F106-F155 AromaticContact CE2-CE1 3.84Å; F106-F155 HydrophobicContact CE2-CE1 3.84Å; F106-F155 HydrophobicContact CE2-CE2 4.49Å; F106-F155 AromaticContact CE2-CZ 3.61Å; F106-F155 HydrophobicContact CE2-CZ 3.61Å; F106-F155 HydrophobicContact CG-CD2 4.13Å; F106-F155 HydrophobicContact CG-CE1 4.04Å; F106-F155 AromaticContact CG-CE2 3.41Å; F106-F155 HydrophobicContact CG-CE2 3.41Å; F106-F155 VanDerWaalsContact CG-CE2 3.41Å; F106-F155 AromaticContact CG-CZ 3.36Å; F106-F155 HydrophobicContact CG-CZ 3.36Å; F106-F155 HydrophobicContact CZ-CD1 4.26Å; F106-F155 AromaticContact CZ-CE1 3.54Å; F106-F155 HydrophobicContact CZ-CE1 3.54Å; F106-F155 AromaticContact CZ-CZ 3.77Å; F106-F155 HydrophobicContact CZ-CZ 3.77Å; Y151-F155 VanDerWaalsContact O-CB 3.32Å; Y151-F155 WeakPolarHBondContact O-CB 3.4Å; Y151-F155 PolarHBondContact O-N 2.95Å; G152-F155 PolarHBondContact O-N 2.86Å; L153-F155 VanDerWaalsContact C-N 3.31Å; L153-F155 PolarHBondContact O-N 3.47Å; F155-A157 VanDerWaalsContact C-N 3.34Å; F155-A157 PolarHBondContact O-N 3.23Å; F155-R158 PolarHBondContact O-N 2.54Å; F155-G159 PolarHBondContact O-N 3.48Å; F155-G159 VanDerWaalsContact O-N 3.15Å
156	I	95.2	Very high	92.8	Very high	100 Å²	100	34.5 Å²	34.5	51%	0.513	19%	0.19	S	C	.	.	H	α-helix	trans	-60.4	-44.4	175.7	-66.9	167.8	0	0	0	110.9	G152 L153 R158 G159 L160	G152-I156 WeakPolarHBondContact O-CG1 3.42Å; G152-I156 PolarHBondContact O-N 3.31Å; L153-I156 PolarHBondContact O-N 3.26Å; I156-R158 VanDerWaalsContact C-N 3.29Å; I156-R158 PolarHBondContact O-N 3.2Å; I156-G159 PolarHBondContact O-N 3.03Å; I156-G159 VanDerWaalsContact O-N 3.15Å; I156-L160 HydrophobicContact CG2-CD1 4.36Å; I156-L160 PolarHBondContact O-N 3.38Å
157	A	95.5	Very high	93.1	Very high	0 Å²	0	35.3 Å²	35.3	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-58.6	-38.8	177.4	0	0	0	0	0	112.4	S141 V144 F145 L153 M154 F155 L160 Q161	S141-A157 WeakPolarHBondContact CB-O 3.24Å; S141-A157 WeakPolarHBondContact O-CB 3.23Å; V144-A157 HydrophobicContact CB-CB 4.36Å; V144-A157 HydrophobicContact CG1-CB 4.08Å; F145-A157 HydrophobicContact CB-CB 4Å; F145-A157 HydrophobicContact CD2-CB 3.92Å; F145-A157 HydrophobicContact CG-CB 4.47Å; L153-A157 WeakPolarHBondContact O-CB 3.21Å; L153-A157 PolarHBondContact O-N 3.02Å; M154-A157 PolarHBondContact O-N 2.91Å; F155-A157 VanDerWaalsContact C-N 3.34Å; F155-A157 PolarHBondContact O-N 3.23Å; A157-L160 PolarHBondContact O-N 2.99Å; A157-Q161 WeakPolarHBondContact O-CG 3.46Å; A157-Q161 PolarHBondContact O-N 3.27Å
158	R	94.1	Very high	93.4	Very high	1 Å²	1	29 Å²	29	0%	0.004	17%	0.167	C	C	.	.	H	α-helix	trans	-65.9	-39	173.9	-75.5	-56.1	-175	83.6	24.2	114.3	L103 K107 F145 M154 F155 I156 L160 Q161 G162	L103-R158 HydrophobicContact CB-CG 4.23Å; L103-R158 HydrophobicContact CD2-CB 4.49Å; L103-R158 HydrophobicContact CD2-CG 3.95Å; K107-R158 HydrophobicContact CB-CB 4.45Å; F145-R158 HydrophobicContact CD2-CG 4.42Å; F145-R158 HydrophobicContact CE2-CG 3.98Å; M154-R158 WeakPolarHBondContact O-CG 3.45Å; M154-R158 PolarHBondContact O-N 3.49Å; F155-R158 PolarHBondContact O-N 2.54Å; I156-R158 VanDerWaalsContact C-N 3.29Å; I156-R158 PolarHBondContact O-N 3.2Å; R158-L160 VanDerWaalsContact C-N 3.32Å; R158-Q161 PolarHBondContact O-N 2.76Å; R158-G162 PolarHBondContact O-N 3Å
159	G	96.5	Very high	94	Very high	6 Å²	6	29.4 Å²	29.4	6%	0.062	17%	0.168	C	C	.	.	H	α-helix	trans	-60	-45.8	172.9	0	0	0	0	0	111.3	F106 I110 F155 I156 Q161 G162 M163	F106-G159 VanDerWaalsContact CE1-CA 3.47Å; I110-G159 WeakPolarHBondContact CG2-O 3.33Å; F155-G159 PolarHBondContact O-N 3.48Å; F155-G159 VanDerWaalsContact O-N 3.15Å; I156-G159 PolarHBondContact O-N 3.03Å; I156-G159 VanDerWaalsContact O-N 3.15Å; G159-Q161 PolarHBondContact O-N 3.24Å; G159-G162 PolarHBondContact O-N 3.24Å; G159-M163 PolarHBondContact O-N 3.44Å; G159-M163 VanDerWaalsContact O-N 3.08Å
160	L	97.3	Very high	94.7	Very high	64 Å²	64	25.6 Å²	25.6	34%	0.335	14%	0.142	S	C	.	.	H	α-helix	trans	-62.6	-39.9	175.9	-66.9	176.6	0	0	0	112.4	I137 S141 I156 A157 R158 G162 M163 G164	I137-L160 HydrophobicContact CG2-CB 4.2Å; I137-L160 WeakPolarHBondContact CG2-O 3.37Å; S141-L160 VanDerWaalsContact CB-CB 3.49Å; I156-L160 HydrophobicContact CG2-CD1 4.36Å; I156-L160 PolarHBondContact O-N 3.38Å; A157-L160 PolarHBondContact O-N 2.99Å; R158-L160 VanDerWaalsContact C-N 3.32Å; L160-G162 VanDerWaalsContact C-N 3.35Å; L160-G162 PolarHBondContact O-N 3.47Å; L160-M163 HydrophobicContact CD2-CE 3.51Å; L160-M163 PolarHBondContact O-N 3.2Å; L160-G164 PolarHBondContact O-N 3.44Å
161	Q	97.1	Very high	95.3	Very high	4 Å²	4	23.2 Å²	23.2	2%	0.019	13%	0.125	C	C	.	.	H	α-helix	trans	-57.8	-47.6	173.2	-74.4	173.7	6.8	0	0	110.9	K107 S141 T142 A157 R158 G159 M163 G164 S165	K107-Q161 HydrophobicContact CG-CB 4.47Å; S141-Q161 WeakPolarHBondContact OG-CG 3.32Å; T142-Q161 PolarHBondContact OG1-NE2 2.93Å; A157-Q161 WeakPolarHBondContact O-CG 3.46Å; A157-Q161 PolarHBondContact O-N 3.27Å; R158-Q161 PolarHBondContact O-N 2.76Å; G159-Q161 PolarHBondContact O-N 3.24Å; Q161-M163 VanDerWaalsContact C-N 3.3Å; Q161-M163 PolarHBondContact O-N 3.49Å; Q161-G164 CarbonylContact O-C 3.59Å; Q161-G164 WeakPolarHBondContact O-CA 3.47Å; Q161-G164 PolarHBondContact O-N 3.33Å; Q161-S165 PolarHBondContact O-N 2.89Å; Q161-S165 PolarHBondContact O-OG 3.41Å
162	G	97.6	Very high	95.9	Very high	0 Å²	0	20.6 Å²	20.6	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-58.4	-39.2	177.5	0	0	0	0	0	113.6	K107 Q111 R158 G159 L160 A166	K107-G162 WeakPolarHBondContact O-CA 3.3Å; Q111-G162 WeakPolarHBondContact CA-O 3.04Å; Q111-G162 WeakPolarHBondContact CB-O 3.39Å; R158-G162 PolarHBondContact O-N 3Å; G159-G162 PolarHBondContact O-N 3.24Å; L160-G162 VanDerWaalsContact C-N 3.35Å; L160-G162 PolarHBondContact O-N 3.47Å; G162-A166 WeakPolarHBondContact O-CB 3.47Å; G162-A166 PolarHBondContact O-N 3.5Å
163	M	98	Very high	96.3	Very high	49 Å²	49	19 Å²	19	24%	0.241	10%	0.097	C	C	.	.	H	α-helix	trans	-64.4	-42.7	171.8	178	174	59.8	0	0	111.6	I110 I137 G159 L160 Q161 A166 F167	I110-M163 HydrophobicContact CG2-CB 3.95Å; I137-M163 HydrophobicContact CD1-CE 3.83Å; I137-M163 HydrophobicContact CD1-CG 4.21Å; I137-M163 HydrophobicContact CD1-SD 4.39Å; I137-M163 HydrophobicContact CG1-CE 4.38Å; I137-M163 HydrophobicContact CG2-CE 4.01Å; G159-M163 PolarHBondContact O-N 3.44Å; G159-M163 VanDerWaalsContact O-N 3.08Å; L160-M163 HydrophobicContact CD2-CE 3.51Å; L160-M163 PolarHBondContact O-N 3.2Å; Q161-M163 VanDerWaalsContact C-N 3.3Å; Q161-M163 PolarHBondContact O-N 3.49Å; M163-A166 PolarHBondContact O-N 2.82Å; M163-F167 HydrophobicContact CG-CD2 4.46Å; M163-F167 HydrophobicContact CG-CE2 4.38Å; M163-F167 WeakPolarHBondContact O-CD2 3.44Å; M163-F167 PolarHBondContact O-N 3.42Å
164	G	98	Very high	96.7	Very high	0 Å²	0	15.5 Å²	15.5	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-60.1	-47.4	175.9	0	0	0	0	0	112.7	G134 L160 Q161 F167 A168	G134-G164 WeakPolarHBondContact CA-O 3.44Å; L160-G164 PolarHBondContact O-N 3.44Å; Q161-G164 CarbonylContact O-C 3.59Å; Q161-G164 WeakPolarHBondContact O-CA 3.47Å; Q161-G164 PolarHBondContact O-N 3.33Å; G164-F167 PolarHBondContact O-N 3.25Å; G164-A168 WeakPolarHBondContact O-CB 3.36Å; G164-A168 PolarHBondContact O-N 3.35Å
165	S	97.8	Very high	97	Very high	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-59.7	-44.9	176.8	-41.4	0	0	0	0	111.3	D36 K107 Q161 F167 A168 D169	D36-S165 VanDerWaalsContact CG-OG 3.27Å; D36-S165 WeakPolarHBondContact OD1-CB 3.49Å; D36-S165 PolarHBondContact OD1-OG 3.02Å; D36-S165 PolarHBondContact OD2-OG 3.26Å; K107-S165 VanDerWaalsContact CE-OG 3.23Å; K107-S165 WeakPolarHBondContact CE-OG 3.38Å; K107-S165 PolarHBondContact NZ-OG 3.29Å; Q161-S165 PolarHBondContact O-N 2.89Å; Q161-S165 PolarHBondContact O-OG 3.41Å; S165-F167 PolarHBondContact O-N 2.93Å; S165-F167 VanDerWaalsContact O-N 3.1Å; S165-A168 PolarHBondContact O-N 3.34Å; S165-A168 VanDerWaalsContact O-N 3.13Å; S165-D169 WeakPolarHBondContact CB-OD2 3.48Å; S165-D169 VanDerWaalsContact O-CB 3.3Å; S165-D169 WeakPolarHBondContact O-CB 3.41Å; S165-D169 VanDerWaalsContact O-CG 3.3Å; S165-D169 PolarHBondContact O-N 3.37Å
166	A	98.4	Very high	97.3	Very high	0 Å²	0	12.5 Å²	12.5	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-53.9	-36.3	177.7	0	0	0	0	0	113.2	Q111 C114 N115 S118 G162 M163 T170	Q111-A166 HydrophobicContact CG-CB 3.99Å; C114-A166 HydrophobicContact CB-CB 3.69Å; N115-A166 VanDerWaalsContact OD1-CA 3.29Å; N115-A166 WeakPolarHBondContact OD1-CA 3.42Å; N115-A166 WeakPolarHBondContact OD1-CB 3.23Å; N115-A166 PolarHBondContact OD1-O 3.5Å; S118-A166 VanDerWaalsContact CB-O 3.31Å; S118-A166 WeakPolarHBondContact CB-O 3.44Å; S118-A166 PolarHBondContact OG-O 3.11Å; G162-A166 WeakPolarHBondContact O-CB 3.47Å; G162-A166 PolarHBondContact O-N 3.5Å; M163-A166 PolarHBondContact O-N 2.82Å; A166-T170 WeakPolarHBondContact O-CB 3.41Å; A166-T170 PolarHBondContact O-OG1 3.12Å
167	F	98.2	Very high	97.4	Very high	18 Å²	18	7.8 Å²	7.8	8%	0.079	4%	0.041	C	C	.	.	H	α-helix	trans	-84	-43.2	175.9	-79.4	-79.2	0	0	0	112.7	V121 P130 F133 M163 G164 S165 A171	V121-F167 HydrophobicContact CB-CE1 4.18Å; V121-F167 HydrophobicContact CG1-CE1 4.18Å; P130-F167 HydrophobicContact CB-CD1 3.9Å; F133-F167 HydrophobicContact CD1-CD1 4.3Å; F133-F167 AromaticContact CD1-CD2 3.97Å; F133-F167 HydrophobicContact CD1-CD2 3.97Å; F133-F167 HydrophobicContact CD1-CE1 4.48Å; F133-F167 HydrophobicContact CD1-CE2 4.21Å; F133-F167 HydrophobicContact CD1-CG 4.03Å; F133-F167 HydrophobicContact CD1-CZ 4.45Å; F133-F167 AromaticContact CE1-CD2 3.88Å; F133-F167 HydrophobicContact CE1-CD2 3.88Å; F133-F167 AromaticContact CE1-CE2 3.77Å; F133-F167 HydrophobicContact CE1-CE2 3.77Å; F133-F167 HydrophobicContact CE1-CG 4.39Å; F133-F167 HydrophobicContact CE1-CZ 4.14Å; M163-F167 HydrophobicContact CG-CD2 4.46Å; M163-F167 HydrophobicContact CG-CE2 4.38Å; M163-F167 WeakPolarHBondContact O-CD2 3.44Å; M163-F167 PolarHBondContact O-N 3.42Å; G164-F167 PolarHBondContact O-N 3.25Å; S165-F167 PolarHBondContact O-N 2.93Å; S165-F167 VanDerWaalsContact O-N 3.1Å; F167-A171 WeakPolarHBondContact O-CB 3.37Å; F167-A171 PolarHBondContact O-N 3.34Å; F167-A171 VanDerWaalsContact O-N 3.17Å
168	A	97.9	Very high	97.4	Very high	1 Å²	1	9.3 Å²	9.3	1%	0.008	5%	0.049	C	C	.	.	H	α-helix	trans	-69.5	-49.7	-176.3	0	0	0	0	0	112.4	L135 I138 G164 S165 G172	L135-A168 HydrophobicContact CD2-CB 4.38Å; L135-A168 HydrophobicContact CG-CB 4.41Å; I138-A168 HydrophobicContact CD1-CB 4.25Å; G164-A168 WeakPolarHBondContact O-CB 3.36Å; G164-A168 PolarHBondContact O-N 3.35Å; S165-A168 PolarHBondContact O-N 3.34Å; S165-A168 VanDerWaalsContact O-N 3.13Å; A168-G172 PolarHBondContact O-N 3.18Å
169	D	97.3	Very high	97.4	Very high	10 Å²	10	11.3 Å²	11.3	5%	0.053	6%	0.057	C	C	.	.	H	α-helix	trans	-70.2	-49.4	-174.5	-58	-14.7	0	0	0	110.5	L33 Q111 S165 A171 G172 L173	L33-D169 HydrophobicContact CD2-CB 3.83Å; L33-D169 WeakPolarHBondContact CD2-OD1 3.4Å; Q111-D169 PolarHBondContact NE2-OD2 3.29Å; S165-D169 WeakPolarHBondContact CB-OD2 3.48Å; S165-D169 VanDerWaalsContact O-CB 3.3Å; S165-D169 WeakPolarHBondContact O-CB 3.41Å; S165-D169 VanDerWaalsContact O-CG 3.3Å; S165-D169 PolarHBondContact O-N 3.37Å; D169-A171 VanDerWaalsContact C-N 3.34Å; D169-A171 PolarHBondContact O-N 2.99Å; D169-G172 PolarHBondContact O-N 3.48Å; D169-L173 WeakPolarHBondContact O-CG 3.29Å; D169-L173 PolarHBondContact O-N 3Å
170	T	97.9	Very high	97.4	Very high	0 Å²	0	11.9 Å²	11.9	0%	0	6%	0.057	C	C	.	.	H	α-helix	trans	-57.6	-47.5	177	-64.8	0	0	0	0	111.2	N115 I122 A166 A174 G397 A401	N115-T170 PolarHBondContact OD1-OG1 3.39Å; I122-T170 HydrophobicContact CD1-CG2 3.47Å; I122-T170 VanDerWaalsContact CD1-CG2 3.47Å; A166-T170 WeakPolarHBondContact O-CB 3.41Å; A166-T170 PolarHBondContact O-OG1 3.12Å; T170-A174 VanDerWaalsContact O-CB 3.23Å; T170-A174 WeakPolarHBondContact O-CB 3.45Å; T170-A174 PolarHBondContact O-N 3.47Å; T170-A174 VanDerWaalsContact O-N 3.08Å; T170-G397 WeakPolarHBondContact CG2-O 3.49Å; T170-A401 HydrophobicContact CG2-CB 3.77Å
171	A	98.1	Very high	97.1	Very high	0 Å²	0	12.6 Å²	12.6	0%	0	6%	0.064	C	C	.	.	H	α-helix	trans	-67.8	-39.1	179.4	0	0	0	0	0	112	I122 Y127 M131 F167 D169 A174 M175	I122-A171 HydrophobicContact CD1-CB 3.76Å; I122-A171 HydrophobicContact CG1-CB 4.17Å; Y127-A171 VanDerWaalsContact O-CB 3.29Å; Y127-A171 WeakPolarHBondContact O-CB 3.44Å; M131-A171 HydrophobicContact CB-CB 3.71Å; M131-A171 HydrophobicContact CG-CB 4.41Å; F167-A171 WeakPolarHBondContact O-CB 3.37Å; F167-A171 PolarHBondContact O-N 3.34Å; F167-A171 VanDerWaalsContact O-N 3.17Å; D169-A171 VanDerWaalsContact C-N 3.34Å; D169-A171 PolarHBondContact O-N 2.99Å; A171-A174 PolarHBondContact O-N 2.84Å; A171-M175 WeakPolarHBondContact O-CB 3.42Å; A171-M175 PolarHBondContact O-N 2.83Å
172	G	97.8	Very high	96.9	Very high	1 Å²	1	16.3 Å²	16.3	1%	0.01	8%	0.084	C	C	.	.	H	α-helix	trans	-61.5	-50.6	178.6	0	0	0	0	0	112.3	A168 D169 A174 M175 I176	A168-G172 PolarHBondContact O-N 3.18Å; D169-G172 PolarHBondContact O-N 3.48Å; G172-A174 PolarHBondContact O-N 3.28Å; G172-M175 PolarHBondContact O-N 3.28Å; G172-I176 PolarHBondContact O-N 3.49Å
173	L	98.1	Very high	96.5	Very high	9 Å²	9	17.6 Å²	17.6	5%	0.047	9%	0.09	C	C	.	.	H	α-helix	trans	-62.5	-42.9	177	-65	177.1	0	0	0	111.8	L33 D169 M175 I176 A177 L190 Y400	L33-L173 HydrophobicContact CD1-CD2 4.06Å; D169-L173 WeakPolarHBondContact O-CG 3.29Å; D169-L173 PolarHBondContact O-N 3Å; L173-M175 VanDerWaalsContact C-N 3.31Å; L173-M175 PolarHBondContact O-N 2.99Å; L173-I176 PolarHBondContact O-N 3.26Å; L173-A177 PolarHBondContact O-N 3.42Å; L173-L190 HydrophobicContact CB-CD2 4.45Å; L173-L190 HydrophobicContact CD2-CD2 3.81Å; L173-Y400 HydrophobicContact CB-CD1 3.69Å; L173-Y400 HydrophobicContact CB-CD2 4.34Å; L173-Y400 HydrophobicContact CB-CE1 4.28Å; L173-Y400 HydrophobicContact CB-CG 3.73Å; L173-Y400 HydrophobicContact CD1-CD1 4.15Å
174	A	97.9	Very high	96.3	Very high	0 Å²	0	18.8 Å²	18.8	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-62.2	-38	175.8	0	0	0	0	0	112.5	Y127 T170 A171 G172 A177 D178 Y400	Y127-A174 HydrophobicContact CD1-CB 3.69Å; Y127-A174 HydrophobicContact CE1-CB 3.76Å; T170-A174 VanDerWaalsContact O-CB 3.23Å; T170-A174 WeakPolarHBondContact O-CB 3.45Å; T170-A174 PolarHBondContact O-N 3.47Å; T170-A174 VanDerWaalsContact O-N 3.08Å; A171-A174 PolarHBondContact O-N 2.84Å; G172-A174 PolarHBondContact O-N 3.28Å; A174-A177 PolarHBondContact O-N 2.87Å; A174-D178 VanDerWaalsContact O-CB 3.32Å; A174-D178 WeakPolarHBondContact O-CB 3.44Å; A174-D178 PolarHBondContact O-N 2.86Å; A174-Y400 VanDerWaalsContact CA-CD2 3.5Å; A174-Y400 HydrophobicContact CB-CD2 3.97Å
175	M	96.7	Very high	96.2	Very high	0 Å²	0	21.9 Å²	21.9	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-68.8	-38.6	177.8	-162.4	-174.2	-54.1	0	0	112	V25 V29 Y127 D128 M131 A171 G172 L173 D178 R179 L235 M239	V25-M175 HydrophobicContact CG1-CB 4.45Å; V25-M175 HydrophobicContact CG1-CG 3.65Å; V25-M175 HydrophobicContact CG1-SD 3.49Å; V25-M175 WeakPolarHBondContact CG1-SD 3.46Å; V25-M175 HydrophobicContact CG2-SD 4.48Å; V29-M175 HydrophobicContact CG2-SD 4.48Å; Y127-M175 HydrophobicContact CG-CB 4.37Å; D128-M175 HydrophobicContact CB-CE 4.04Å; M131-M175 HydrophobicContact CB-CE 4.48Å; M131-M175 HydrophobicContact SD-CE 3.66Å; A171-M175 WeakPolarHBondContact O-CB 3.42Å; A171-M175 PolarHBondContact O-N 2.83Å; G172-M175 PolarHBondContact O-N 3.28Å; L173-M175 VanDerWaalsContact C-N 3.31Å; L173-M175 PolarHBondContact O-N 2.99Å; M175-D178 PolarHBondContact O-N 3.38Å; M175-R179 WeakPolarHBondContact O-CB 3.29Å; M175-R179 VanDerWaalsContact O-CG 3.3Å; M175-R179 WeakPolarHBondContact O-CG 3.21Å; M175-R179 PolarHBondContact O-N 3.31Å; M175-L235 HydrophobicContact CE-CD1 3.81Å; M175-L235 HydrophobicContact CE-CD2 4.43Å; M175-L235 HydrophobicContact SD-CD1 3.82Å; M175-M239 HydrophobicContact CE-CE 4.27Å; M175-M239 HydrophobicContact CG-CE 3.95Å; M175-M239 HydrophobicContact CG-SD 4.28Å; M175-M239 HydrophobicContact SD-CE 3.71Å; M175-M239 HydrophobicContact SD-CG 4.07Å; M175-M239 HydrophobicContact SD-SD 3.57Å
176	I	97.7	Very high	96.1	Very high	0 Å²	0	21.9 Å²	21.9	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-60.1	-49.9	170.8	-69.1	172.5	0	0	0	109.8	L26 V29 G172 L173 D178 R179 Y180 A189 L190 A193	L26-I176 HydrophobicContact CD1-CD1 3.63Å; L26-I176 HydrophobicContact CD1-CG1 4.06Å; V29-I176 HydrophobicContact CB-CD1 4Å; V29-I176 HydrophobicContact CB-CG1 4.2Å; V29-I176 HydrophobicContact CG1-CD1 3.48Å; V29-I176 VanDerWaalsContact CG1-CD1 3.48Å; V29-I176 HydrophobicContact CG1-CG1 4.02Å; V29-I176 HydrophobicContact CG2-CG1 4.34Å; G172-I176 PolarHBondContact O-N 3.49Å; L173-I176 PolarHBondContact O-N 3.26Å; I176-D178 VanDerWaalsContact C-N 3.27Å; I176-D178 PolarHBondContact O-N 3.39Å; I176-R179 PolarHBondContact O-N 2.89Å; I176-Y180 HydrophobicContact CG2-CD2 3.95Å; I176-Y180 WeakPolarHBondContact O-CB 3.47Å; I176-Y180 WeakPolarHBondContact O-CD2 3.41Å; I176-Y180 PolarHBondContact O-N 3.27Å; I176-A189 HydrophobicContact CG2-CB 3.55Å; I176-L190 HydrophobicContact CB-CD2 4.07Å; I176-L190 HydrophobicContact CD1-CD2 4.45Å; I176-L190 HydrophobicContact CG2-CD2 3.79Å; I176-L190 HydrophobicContact CG2-CG 3.9Å; I176-A193 HydrophobicContact CD1-CB 3.73Å
177	A	97.1	Very high	96	Very high	0 Å²	0	22 Å²	22	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-63.1	-33.2	-179.2	0	0	0	0	0	113.4	L173 A174 Y396 Y400	L173-A177 PolarHBondContact O-N 3.42Å; A174-A177 PolarHBondContact O-N 2.87Å; A177-Y396 HydrophobicContact CB-CD1 3.95Å; A177-Y396 HydrophobicContact CB-CD2 4.15Å; A177-Y396 HydrophobicContact CB-CE1 4.27Å; A177-Y396 HydrophobicContact CB-CE2 4.47Å; A177-Y396 HydrophobicContact CB-CG 3.87Å; A177-Y400 HydrophobicContact CB-CD2 4.4Å; A177-Y400 HydrophobicContact CB-CE2 3.33Å
178	D	95.4	Very high	96	Very high	33 Å²	33	25.9 Å²	25.9	18%	0.176	13%	0.125	C	C	.	.	H	α-helix	trans	-70.3	-40	176.2	-171.2	92.4	0	0	0	112.8	Y127 A174 M175 I176 Y396	Y127-D178 HydrophobicContact CD2-CB 4.42Å; Y127-D178 HydrophobicContact CE2-CB 3.67Å; Y127-D178 VanDerWaalsContact CE2-OD1 3.26Å; Y127-D178 WeakPolarHBondContact CE2-OD1 3.37Å; Y127-D178 PolarHBondContact OH-OD1 3.39Å; A174-D178 VanDerWaalsContact O-CB 3.32Å; A174-D178 WeakPolarHBondContact O-CB 3.44Å; A174-D178 PolarHBondContact O-N 2.86Å; M175-D178 PolarHBondContact O-N 3.38Å; I176-D178 VanDerWaalsContact C-N 3.27Å; I176-D178 PolarHBondContact O-N 3.39Å; D178-Y396 HydrophobicContact CB-CD2 3.97Å; D178-Y396 HydrophobicContact CB-CE2 4.12Å
179	R	94.9	Very high	96	Very high	43 Å²	43	25.9 Å²	25.9	16%	0.162	13%	0.125	C	C	.	.	H	α-helix	trans	-83.6	-23.5	-179	-64.9	-63.6	94.3	170.4	-0.1	113.8	R22 V25 M175 I176 E245	R22-R179 HydrophobicContact CB-CB 3.99Å; V25-R179 HydrophobicContact CG1-CG 4.24Å; M175-R179 WeakPolarHBondContact O-CB 3.29Å; M175-R179 VanDerWaalsContact O-CG 3.3Å; M175-R179 WeakPolarHBondContact O-CG 3.21Å; M175-R179 PolarHBondContact O-N 3.31Å; I176-R179 PolarHBondContact O-N 2.89Å; R179-E245 IonicContact NH1-OE2 3.8Å
180	Y	96	Very high	96	Very high	17 Å²	17	25.4 Å²	25.4	7%	0.067	12%	0.122	C	C	.	.			trans	-110.4	87.2	177.7	-68.8	-88.6	0	0	0	109.8	R22 L26 I176 E185 R186 A189	R22-Y180 HydrophobicContact CB-CE2 4.25Å; R22-Y180 HydrophobicContact CG-CE1 4.37Å; R22-Y180 PolarHBondContact O-OH 3.35Å; L26-Y180 HydrophobicContact CB-CE2 4.08Å; L26-Y180 HydrophobicContact CD2-CE2 4.47Å; I176-Y180 HydrophobicContact CG2-CD2 3.95Å; I176-Y180 WeakPolarHBondContact O-CB 3.47Å; I176-Y180 WeakPolarHBondContact O-CD2 3.41Å; I176-Y180 PolarHBondContact O-N 3.27Å; Y180-E185 HydrophobicContact CD1-CB 3.92Å; Y180-R186 WeakPolarHBondContact O-CB 3.36Å; Y180-A189 HydrophobicContact CD1-CB 4.08Å; Y180-A189 HydrophobicContact CD2-CB 3.69Å; Y180-A189 HydrophobicContact CE1-CB 4.17Å; Y180-A189 HydrophobicContact CE2-CB 3.82Å; Y180-A189 HydrophobicContact CG-CB 3.82Å
181	T	91.6	Very high	96	Very high	79 Å²	79	25.4 Å²	25.4	49%	0.485	12%	0.122	S	C	.	.			trans	-77.3	-33.1	-176.1	55.1	0	0	0	0	112.8	E183 R456	T181-E183 PolarHBondContact O-N 2.93Å; T181-R456 PolarHBondContact O-NH1 3.18Å
182	N	92	Very high	96	Very high	82 Å²	82	28.3 Å²	28.3	44%	0.439	14%	0.137	S	C	.	.	S	Bend	trans	-67.3	131.1	175.6	-178.5	-66	0	0	0	110.5	Y184 E185 R186	N182-Y184 PolarHBondContact O-N 3.45Å; N182-Y184 PolarHBondContact OD1-N 3.27Å; N182-E185 HydrophobicContact CB-CB 4.08Å; N182-E185 HydrophobicContact CB-CG 3.93Å; N182-E185 PolarHBondContact O-N 3.31Å; N182-E185 PolarHBondContact OD1-N 3.26Å; N182-R186 VanDerWaalsContact O-CB 3.28Å; N182-R186 WeakPolarHBondContact O-CB 3.37Å; N182-R186 PolarHBondContact O-N 3.16Å
183	E	89.6	Confident	96	Very high	27 Å²	27	28.2 Å²	28.2	13%	0.126	14%	0.136	C	C	.	.	H	α-helix	trans	-56.1	-44.6	-176.1	-176.4	63.8	-161	0	0	113.5	T181 R186 T187 Q335 Y452 R456	T181-E183 PolarHBondContact O-N 2.93Å; E183-R186 IonicContact OE1-NH2 3.51Å; E183-R186 IonicContact OE2-CZ 3.93Å; E183-R186 IonicContact OE2-NE 3.86Å; E183-R186 IonicContact OE2-NH2 3.46Å; E183-R186 PolarHBondContact OE2-NH2 3.49Å; E183-T187 WeakPolarHBondContact O-CB 3.36Å; E183-T187 PolarHBondContact O-N 3Å; E183-T187 PolarHBondContact O-OG1 3.03Å; E183-Q335 PolarHBondContact OE1-NE2 2.97Å; E183-Y452 HydrophobicContact CG-CE1 4.42Å; E183-Y452 PolarHBondContact OE1-OH 3.3Å; E183-Y452 VanDerWaalsContact OE1-OH 3.06Å; E183-R456 IonicContact OE2-CZ 3.89Å; E183-R456 IonicContact OE2-NH2 2.72Å; E183-R456 PolarHBondContact OE2-NH2 3.28Å
184	Y	93.2	Very high	95.9	Very high	74 Å²	74	28.1 Å²	28.1	29%	0.29	14%	0.136	S	C	.	.	H	α-helix	trans	-70.8	-44.6	-179.9	171.3	-112.6	0	0	0	111.2	N182 R186 T187 K188 I325 D329	N182-Y184 PolarHBondContact O-N 3.45Å; N182-Y184 PolarHBondContact OD1-N 3.27Å; Y184-R186 VanDerWaalsContact C-N 3.28Å; Y184-R186 PolarHBondContact O-N 2.96Å; Y184-T187 PolarHBondContact O-N 2.84Å; Y184-K188 WeakPolarHBondContact O-CB 3.45Å; Y184-K188 PolarHBondContact O-N 3.19Å; Y184-I325 HydrophobicContact CE2-CG2 4.09Å; Y184-D329 HydrophobicContact CD2-CB 3.85Å; Y184-D329 HydrophobicContact CE2-CB 3.33Å; Y184-D329 VanDerWaalsContact CZ-OD2 3.23Å; Y184-D329 PolarHBondContact OH-OD2 3.19Å
185	E	95.9	Very high	95.8	Very high	66 Å²	66	29 Å²	29	31%	0.308	14%	0.143	S	C	.	.	H	α-helix	trans	-63.5	-36.7	177.2	-60.3	-170.4	142.5	0	0	111.7	R22 Y180 N182 K188 A189	R22-E185 IonicContact CZ-OE2 3.68Å; R22-E185 IonicContact NH1-OE1 3.69Å; R22-E185 IonicContact NH1-OE2 2.68Å; R22-E185 PolarHBondContact NH1-OE2 3.05Å; R22-E185 IonicContact NH2-OE1 3.5Å; R22-E185 IonicContact NH2-OE2 3.84Å; Y180-E185 HydrophobicContact CD1-CB 3.92Å; N182-E185 HydrophobicContact CB-CB 4.08Å; N182-E185 HydrophobicContact CB-CG 3.93Å; N182-E185 PolarHBondContact O-N 3.31Å; N182-E185 PolarHBondContact OD1-N 3.26Å; E185-K188 PolarHBondContact O-N 2.88Å; E185-A189 VanDerWaalsContact O-CB 3.31Å; E185-A189 WeakPolarHBondContact O-CB 3.23Å; E185-A189 PolarHBondContact O-N 3.01Å
186	R	96.4	Very high	95.8	Very high	0 Å²	0	32 Å²	32	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-63.1	-48	173.5	-172.7	167.1	63.9	-168.7	1.8	111.7	Y180 N182 E183 Y184 K188 A189 L190 P382 D389	Y180-R186 WeakPolarHBondContact O-CB 3.36Å; N182-R186 VanDerWaalsContact O-CB 3.28Å; N182-R186 WeakPolarHBondContact O-CB 3.37Å; N182-R186 PolarHBondContact O-N 3.16Å; E183-R186 IonicContact OE1-NH2 3.51Å; E183-R186 IonicContact OE2-CZ 3.93Å; E183-R186 IonicContact OE2-NE 3.86Å; E183-R186 IonicContact OE2-NH2 3.46Å; E183-R186 PolarHBondContact OE2-NH2 3.49Å; Y184-R186 VanDerWaalsContact C-N 3.28Å; Y184-R186 PolarHBondContact O-N 2.96Å; R186-K188 VanDerWaalsContact C-N 3.28Å; R186-K188 PolarHBondContact O-N 3.2Å; R186-A189 PolarHBondContact O-N 3.45Å; R186-L190 HydrophobicContact CG-CD1 3.77Å; R186-L190 HydrophobicContact CG-CG 4.35Å; R186-L190 WeakPolarHBondContact O-CB 3.45Å; R186-L190 WeakPolarHBondContact O-CG 3.37Å; R186-L190 PolarHBondContact O-N 2.82Å; R186-P382 PolarHBondContact NH2-O 3.16Å; R186-D389 IonicContact CZ-OD2 2.65Å; R186-D389 IonicContact NH1-OD2 2.79Å; R186-D389 PolarHBondContact NH1-OD2 3.42Å; R186-D389 IonicContact NH2-OD2 3.99Å
187	T	96.5	Very high	95.5	Very high	1 Å²	1	33.8 Å²	33.8	1%	0.006	17%	0.165	C	C	.	.	H	α-helix	trans	-56.9	-45	175.9	-58.7	0	0	0	0	111	E183 Y184 G191 A328 P382	E183-T187 WeakPolarHBondContact O-CB 3.36Å; E183-T187 PolarHBondContact O-N 3Å; E183-T187 PolarHBondContact O-OG1 3.03Å; Y184-T187 PolarHBondContact O-N 2.84Å; T187-G191 PolarHBondContact O-N 2.88Å; T187-A328 HydrophobicContact CG2-CB 3.81Å; T187-P382 HydrophobicContact CG2-CG 4.07Å; T187-P382 WeakPolarHBondContact OG1-CB 3.42Å
188	K	97.8	Very high	95.3	Very high	101 Å²	101	34.4 Å²	34.4	44%	0.439	17%	0.17	S	C	.	.	H	α-helix	trans	-63.3	-45.9	176.3	-176.5	178.2	179.5	177.5	0	112.3	Y184 E185 R186 G191 I192 I325	Y184-K188 WeakPolarHBondContact O-CB 3.45Å; Y184-K188 PolarHBondContact O-N 3.19Å; E185-K188 PolarHBondContact O-N 2.88Å; R186-K188 VanDerWaalsContact C-N 3.28Å; R186-K188 PolarHBondContact O-N 3.2Å; K188-G191 PolarHBondContact O-N 3.48Å; K188-I192 HydrophobicContact CG-CD1 4.05Å; K188-I192 WeakPolarHBondContact O-CD1 3.41Å; K188-I192 WeakPolarHBondContact O-CG1 3.42Å; K188-I192 PolarHBondContact O-N 3.17Å; K188-I325 HydrophobicContact CB-CG2 4.2Å; K188-I325 HydrophobicContact CG-CG2 4.32Å
189	A	98.3	Very high	95.2	Very high	1 Å²	1	37.2 Å²	37.2	1%	0.008	18%	0.181	C	C	.	.	H	α-helix	trans	-67.2	-46.7	-177.7	0	0	0	0	0	112.2	L26 I176 Y180 E185 R186 I192 A193	L26-A189 HydrophobicContact CD1-CB 4.13Å; L26-A189 WeakPolarHBondContact CD1-O 3.4Å; L26-A189 HydrophobicContact CD2-CB 4.11Å; I176-A189 HydrophobicContact CG2-CB 3.55Å; Y180-A189 HydrophobicContact CD1-CB 4.08Å; Y180-A189 HydrophobicContact CD2-CB 3.69Å; Y180-A189 HydrophobicContact CE1-CB 4.17Å; Y180-A189 HydrophobicContact CE2-CB 3.82Å; Y180-A189 HydrophobicContact CG-CB 3.82Å; E185-A189 VanDerWaalsContact O-CB 3.31Å; E185-A189 WeakPolarHBondContact O-CB 3.23Å; E185-A189 PolarHBondContact O-N 3.01Å; R186-A189 PolarHBondContact O-N 3.45Å; A189-I192 PolarHBondContact O-N 3.18Å; A189-A193 PolarHBondContact O-N 3.31Å
190	L	97.9	Very high	95	Very high	0 Å²	0	35.2 Å²	35.2	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-63.8	-40.2	174.7	-69.8	169.8	0	0	0	111.5	L173 I176 R186 I192 A193 L194 L381 P382 Y400	L173-L190 HydrophobicContact CB-CD2 4.45Å; L173-L190 HydrophobicContact CD2-CD2 3.81Å; I176-L190 HydrophobicContact CB-CD2 4.07Å; I176-L190 HydrophobicContact CD1-CD2 4.45Å; I176-L190 HydrophobicContact CG2-CD2 3.79Å; I176-L190 HydrophobicContact CG2-CG 3.9Å; R186-L190 HydrophobicContact CG-CD1 3.77Å; R186-L190 HydrophobicContact CG-CG 4.35Å; R186-L190 WeakPolarHBondContact O-CB 3.45Å; R186-L190 WeakPolarHBondContact O-CG 3.37Å; R186-L190 PolarHBondContact O-N 2.82Å; L190-I192 PolarHBondContact O-N 3.31Å; L190-A193 WeakPolarHBondContact O-CB 3.37Å; L190-A193 PolarHBondContact O-N 3.41Å; L190-L194 WeakPolarHBondContact O-CG 3.21Å; L190-L194 PolarHBondContact O-N 2.99Å; L190-L381 HydrophobicContact CD1-CB 4.24Å; L190-P382 HydrophobicContact CD1-CB 4.28Å; L190-P382 HydrophobicContact CD1-CG 3.98Å; L190-Y400 HydrophobicContact CD1-CE1 4.41Å; L190-Y400 WeakPolarHBondContact CD1-OH 3.5Å
191	G	97.5	Very high	94.6	Very high	0 Å²	0	36 Å²	36	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-61.5	-41.6	173.9	0	0	0	0	0	112.8	T187 K188 A193 L194 A195 V321	T187-G191 PolarHBondContact O-N 2.88Å; K188-G191 PolarHBondContact O-N 3.48Å; G191-A193 VanDerWaalsContact C-N 3.31Å; G191-A193 PolarHBondContact O-N 3.1Å; G191-L194 PolarHBondContact O-N 3.39Å; G191-A195 PolarHBondContact O-N 3.37Å; G191-V321 WeakPolarHBondContact O-CG1 3.35Å
192	I	98	Very high	94.5	Very high	60 Å²	60	34.3 Å²	34.3	31%	0.308	17%	0.169	S	C	.	.	H	α-helix	trans	-60.1	-43.8	173.2	-69.6	162.9	0	0	0	110.5	L26 K188 A189 L190 L194 A195 F196	L26-I192 HydrophobicContact CD2-CD1 4.3Å; K188-I192 HydrophobicContact CG-CD1 4.05Å; K188-I192 WeakPolarHBondContact O-CD1 3.41Å; K188-I192 WeakPolarHBondContact O-CG1 3.42Å; K188-I192 PolarHBondContact O-N 3.17Å; A189-I192 PolarHBondContact O-N 3.18Å; L190-I192 PolarHBondContact O-N 3.31Å; I192-L194 PolarHBondContact O-N 2.96Å; I192-A195 WeakPolarHBondContact O-CB 3.46Å; I192-A195 PolarHBondContact O-N 3.1Å; I192-A195 VanDerWaalsContact O-N 3.16Å; I192-F196 HydrophobicContact CG2-CD2 4.16Å; I192-F196 HydrophobicContact CG2-CE2 4.09Å; I192-F196 WeakPolarHBondContact O-CD2 3.46Å; I192-F196 PolarHBondContact O-N 3.24Å; I192-F196 VanDerWaalsContact O-N 3.13Å
193	A	97.9	Very high	94.4	Very high	0 Å²	0	32.9 Å²	32.9	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-59.5	-43.8	176.3	0	0	0	0	0	112.5	L33 I176 A189 L190 G191 A195 F196 I197	L33-A193 HydrophobicContact CD1-CB 3.74Å; I176-A193 HydrophobicContact CD1-CB 3.73Å; A189-A193 PolarHBondContact O-N 3.31Å; L190-A193 WeakPolarHBondContact O-CB 3.37Å; L190-A193 PolarHBondContact O-N 3.41Å; G191-A193 VanDerWaalsContact C-N 3.31Å; G191-A193 PolarHBondContact O-N 3.1Å; A193-A195 VanDerWaalsContact C-N 3.33Å; A193-A195 PolarHBondContact O-N 3.04Å; A193-F196 WeakPolarHBondContact O-CB 3.18Å; A193-F196 PolarHBondContact O-N 3.27Å; A193-F196 VanDerWaalsContact O-N 3.17Å; A193-I197 PolarHBondContact O-N 3.1Å
194	L	95.9	Very high	94.4	Very high	7 Å²	7	31.6 Å²	31.6	4%	0.037	16%	0.157	C	C	.	.	H	α-helix	trans	-63.1	-35.2	173.6	-67.8	176.5	0	0	0	113.3	L190 G191 I192 F196 I197 S198 V321 D377 L381	L190-L194 WeakPolarHBondContact O-CG 3.21Å; L190-L194 PolarHBondContact O-N 2.99Å; G191-L194 PolarHBondContact O-N 3.39Å; I192-L194 PolarHBondContact O-N 2.96Å; L194-F196 VanDerWaalsContact C-N 3.29Å; L194-F196 PolarHBondContact O-N 3.4Å; L194-I197 HydrophobicContact CD2-CD1 4.08Å; L194-I197 WeakPolarHBondContact O-CB 3.32Å; L194-I197 PolarHBondContact O-N 3.07Å; L194-S198 PolarHBondContact O-N 2.99Å; L194-V321 HydrophobicContact CB-CG2 4.45Å; L194-D377 HydrophobicContact CD1-CB 3.65Å; L194-D377 HydrophobicContact CD2-CB 4.37Å; L194-L381 HydrophobicContact CD1-CD1 4.06Å; L194-L381 HydrophobicContact CD2-CD1 3.83Å; L194-L381 HydrophobicContact CG-CD1 4.16Å
195	A	96.1	Very high	94.1	Very high	19 Å²	19	30.1 Å²	30.1	16%	0.157	16%	0.156	C	C	.	.	H	α-helix	trans	-65.2	-35.1	175	0	0	0	0	0	111.8	G191 I192 A193 S198 F199 V318	G191-A195 PolarHBondContact O-N 3.37Å; I192-A195 WeakPolarHBondContact O-CB 3.46Å; I192-A195 PolarHBondContact O-N 3.1Å; I192-A195 VanDerWaalsContact O-N 3.16Å; A193-A195 VanDerWaalsContact C-N 3.33Å; A193-A195 PolarHBondContact O-N 3.04Å; A195-S198 PolarHBondContact O-N 3Å; A195-F199 WeakPolarHBondContact O-CB 3.34Å; A195-F199 PolarHBondContact O-N 3.39Å; A195-V318 HydrophobicContact CB-CG2 4.49Å
196	F	95.8	Very high	93.7	Very high	62 Å²	62	29.9 Å²	29.9	27%	0.272	16%	0.16	S	C	.	.	H	α-helix	trans	-68.9	-34.7	175.6	-91.3	-108.8	0	0	0	112.9	C30 I31 L34 I192 A193 L194 F199 G200	C30-F196 HydrophobicContact CB-CB 4.08Å; C30-F196 HydrophobicContact CB-CD1 3.63Å; C30-F196 HydrophobicContact CB-CD2 3.97Å; C30-F196 HydrophobicContact CB-CE1 3.98Å; C30-F196 HydrophobicContact CB-CE2 4.29Å; C30-F196 HydrophobicContact CB-CG 3.62Å; C30-F196 HydrophobicContact CB-CZ 4.3Å; I31-F196 HydrophobicContact CD1-CE1 4.5Å; L34-F196 HydrophobicContact CB-CB 4.38Å; L34-F196 HydrophobicContact CB-CD1 4.28Å; L34-F196 HydrophobicContact CD1-CD1 3.72Å; L34-F196 HydrophobicContact CD1-CE1 4.33Å; I192-F196 HydrophobicContact CG2-CD2 4.16Å; I192-F196 HydrophobicContact CG2-CE2 4.09Å; I192-F196 WeakPolarHBondContact O-CD2 3.46Å; I192-F196 PolarHBondContact O-N 3.24Å; I192-F196 VanDerWaalsContact O-N 3.13Å; A193-F196 WeakPolarHBondContact O-CB 3.18Å; A193-F196 PolarHBondContact O-N 3.27Å; A193-F196 VanDerWaalsContact O-N 3.17Å; L194-F196 VanDerWaalsContact C-N 3.29Å; L194-F196 PolarHBondContact O-N 3.4Å; F196-F199 PolarHBondContact O-N 3.27Å; F196-G200 PolarHBondContact O-N 3.21Å
197	I	92.7	Very high	93.4	Very high	38 Å²	38	32.2 Å²	32.2	20%	0.195	17%	0.171	C	C	.	.	H	α-helix	trans	-55.9	-52.7	170.1	-73.9	173	0	0	0	110.3	L33 N37 A193 L194 F199 G200 S201	L33-I197 HydrophobicContact CB-CD1 4.2Å; L33-I197 HydrophobicContact CB-CG1 3.74Å; L33-I197 HydrophobicContact CD1-CD1 4.29Å; L33-I197 HydrophobicContact CD2-CD1 4.31Å; N37-I197 HydrophobicContact CB-CG2 4.44Å; N37-I197 VanDerWaalsContact CG-CG2 3.48Å; N37-I197 WeakPolarHBondContact ND2-CG1 3.29Å; N37-I197 VanDerWaalsContact ND2-CG2 3.29Å; N37-I197 WeakPolarHBondContact ND2-CG2 3.37Å; A193-I197 PolarHBondContact O-N 3.1Å; L194-I197 HydrophobicContact CD2-CD1 4.08Å; L194-I197 WeakPolarHBondContact O-CB 3.32Å; L194-I197 PolarHBondContact O-N 3.07Å; I197-F199 VanDerWaalsContact C-N 3.28Å; I197-F199 PolarHBondContact O-N 2.9Å; I197-G200 PolarHBondContact O-N 3.26Å; I197-S201 PolarHBondContact O-N 3.39Å; I197-S201 VanDerWaalsContact O-N 3.12Å; I197-S201 PolarHBondContact O-OG 3.43Å
198	S	91.1	Very high	92.9	Very high	13 Å²	13	32.1 Å²	32.1	9%	0.091	17%	0.17	C	C	.	.	H	α-helix	trans	-63.1	-36.2	178.5	-68.4	0	0	0	0	112.8	L194 A195 G200 S201 L202 F314 H317	L194-S198 PolarHBondContact O-N 2.99Å; A195-S198 PolarHBondContact O-N 3Å; S198-G200 VanDerWaalsContact C-N 3.34Å; S198-S201 PolarHBondContact O-N 3.17Å; S198-L202 PolarHBondContact O-N 2.99Å; S198-F314 VanDerWaalsContact O-CD2 3.28Å; S198-F314 WeakPolarHBondContact O-CD2 3.25Å; S198-H317 PolarHBondContact OG-CE1 3.33Å; S198-H317 VanDerWaalsContact OG-CG 3.23Å; S198-H317 PolarHBondContact OG-ND1 3.44Å
199	F	93.4	Very high	92.2	Very high	92 Å²	92	28.4 Å²	28.4	40%	0.404	16%	0.161	S	C	.	.	H	α-helix	trans	-66.5	-39.1	177.6	-176.5	-112	0	0	0	111.4	L34 A195 F196 I197 S201 L202 V203 F314	L34-F199 HydrophobicContact CD1-CD1 3.68Å; L34-F199 HydrophobicContact CD1-CE1 4.25Å; A195-F199 WeakPolarHBondContact O-CB 3.34Å; A195-F199 PolarHBondContact O-N 3.39Å; F196-F199 PolarHBondContact O-N 3.27Å; I197-F199 VanDerWaalsContact C-N 3.28Å; I197-F199 PolarHBondContact O-N 2.9Å; F199-S201 PolarHBondContact O-N 2.95Å; F199-L202 PolarHBondContact O-N 2.73Å; F199-V203 HydrophobicContact CD1-CG2 4.38Å; F199-V203 HydrophobicContact CD2-CG2 4.1Å; F199-V203 HydrophobicContact CE1-CG2 3.98Å; F199-V203 HydrophobicContact CE2-CG2 3.66Å; F199-V203 HydrophobicContact CG-CG2 4.45Å; F199-V203 HydrophobicContact CZ-CG2 3.6Å; F199-V203 WeakPolarHBondContact O-CG2 3.46Å; F199-V203 PolarHBondContact O-N 3.3Å; F199-F314 VanDerWaalsContact CA-CE2 3.42Å; F199-F314 HydrophobicContact CB-CE2 3.87Å; F199-F314 HydrophobicContact CB-CZ 4.24Å; F199-F314 HydrophobicContact CD2-CE2 4.23Å; F199-F314 AromaticContact CD2-CZ 3.88Å; F199-F314 HydrophobicContact CD2-CZ 3.88Å
200	G	91.6	Very high	91.8	Very high	0 Å²	0	33 Å²	33	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-56.3	-48.5	170.6	0	0	0	0	0	111.9	F196 I197 S198 L202 V203 A204	F196-G200 PolarHBondContact O-N 3.21Å; I197-G200 PolarHBondContact O-N 3.26Å; S198-G200 VanDerWaalsContact C-N 3.34Å; G200-L202 VanDerWaalsContact C-N 3.31Å; G200-L202 PolarHBondContact O-N 2.81Å; G200-V203 PolarHBondContact O-N 2.83Å; G200-A204 WeakPolarHBondContact O-CB 3.39Å; G200-A204 PolarHBondContact O-N 3.2Å
201	S	86.7	Confident	91.5	Very high	33 Å²	33	34.1 Å²	34.1	23%	0.231	19%	0.191	C	C	.	.	H	α-helix	trans	-62.5	-33.6	177.9	-60.5	0	0	0	0	113.6	I197 S198 F199 P205	I197-S201 PolarHBondContact O-N 3.39Å; I197-S201 VanDerWaalsContact O-N 3.12Å; I197-S201 PolarHBondContact O-OG 3.43Å; S198-S201 PolarHBondContact O-N 3.17Å; F199-S201 PolarHBondContact O-N 2.95Å; S201-P205 WeakPolarHBondContact O-CD 3.27Å
202	L	89.7	Confident	91	Very high	45 Å²	45	36 Å²	36	24%	0.236	20%	0.198	C	C	.	.	H	α-helix	trans	-70.8	-47.2	175.7	177	69.5	0	0	0	112.2	S198 F199 G200 P206 L311 F314	S198-L202 PolarHBondContact O-N 2.99Å; F199-L202 PolarHBondContact O-N 2.73Å; G200-L202 VanDerWaalsContact C-N 3.31Å; G200-L202 PolarHBondContact O-N 2.81Å; L202-P206 VanDerWaalsContact O-CD 3.26Å; L202-P206 WeakPolarHBondContact O-CD 3.35Å; L202-L311 HydrophobicContact CD1-CB 4.31Å; L202-L311 HydrophobicContact CD1-CD2 3.55Å; L202-F314 HydrophobicContact CB-CB 4.26Å; L202-F314 HydrophobicContact CB-CD2 3.93Å; L202-F314 HydrophobicContact CB-CE2 4.48Å; L202-F314 HydrophobicContact CB-CG 3.99Å; L202-F314 HydrophobicContact CD1-CB 4.16Å; L202-F314 HydrophobicContact CD1-CG 4.41Å; L202-F314 HydrophobicContact CD2-CB 4.35Å; L202-F314 HydrophobicContact CD2-CD1 3.47Å; L202-F314 VanDerWaalsContact CD2-CD1 3.47Å; L202-F314 HydrophobicContact CD2-CD2 4.22Å; L202-F314 HydrophobicContact CD2-CE1 3.71Å; L202-F314 HydrophobicContact CD2-CE2 4.46Å; L202-F314 HydrophobicContact CD2-CG 3.73Å; L202-F314 HydrophobicContact CD2-CZ 4.2Å; L202-F314 HydrophobicContact CG-CB 4.49Å; L202-F314 HydrophobicContact CG-CD1 4.44Å; L202-F314 HydrophobicContact CG-CG 4.25Å
203	V	90.2	Very high	90.4	Very high	51 Å²	51	40.1 Å²	40.1	31%	0.309	22%	0.216	S	C	.	.	H	α-helix	trans	-77.9	-27.1	-172.9	174.2	0	0	0	0	111.7	M38 F199 G200 P206 F207	M38-V203 HydrophobicContact CE-CG1 4.16Å; F199-V203 HydrophobicContact CD1-CG2 4.38Å; F199-V203 HydrophobicContact CD2-CG2 4.1Å; F199-V203 HydrophobicContact CE1-CG2 3.98Å; F199-V203 HydrophobicContact CE2-CG2 3.66Å; F199-V203 HydrophobicContact CG-CG2 4.45Å; F199-V203 HydrophobicContact CZ-CG2 3.6Å; F199-V203 WeakPolarHBondContact O-CG2 3.46Å; F199-V203 PolarHBondContact O-N 3.3Å; G200-V203 PolarHBondContact O-N 2.83Å; V203-P206 WeakPolarHBondContact O-CD 3.23Å; V203-F207 HydrophobicContact CG1-CB 4.29Å; V203-F207 WeakPolarHBondContact O-CB 3.31Å; V203-F207 PolarHBondContact O-N 2.89Å
204	A	90.5	Very high	90.1	Very high	0 Å²	0	48 Å²	48	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-63.8	-45.6	-172.3	0	0	0	0	0	115.6	M38 M41 V42 G200 F207 G208	M38-A204 HydrophobicContact CB-CB 4.2Å; M38-A204 HydrophobicContact CE-CB 4.4Å; M38-A204 HydrophobicContact CG-CB 4.13Å; M41-A204 HydrophobicContact CB-CB 3.62Å; V42-A204 HydrophobicContact CB-CB 4.41Å; G200-A204 WeakPolarHBondContact O-CB 3.39Å; G200-A204 PolarHBondContact O-N 3.2Å; A204-F207 PolarHBondContact O-N 3.32Å; A204-G208 PolarHBondContact O-N 2.79Å
205	P	86.4	Confident	89.9	Confident	44 Å²	44	54.2 Å²	54.2	29%	0.286	27%	0.274	S	S	.	.	H	α-helix	trans	-65.4	-46	178.5	-18	29.3	0	0	0	113.3	S201 G209	S201-P205 WeakPolarHBondContact O-CD 3.27Å; P205-G209 PolarHBondContact O-N 3.03Å
206	P	87.1	Confident	89.5	Confident	60 Å²	60	54.5 Å²	54.5	39%	0.39	28%	0.279	S	S	.	.	H	α-helix	trans	-60.5	-45.8	172.5	-24.5	34.5	0	0	0	112.9	L202 V203 I210	L202-P206 VanDerWaalsContact O-CD 3.26Å; L202-P206 WeakPolarHBondContact O-CD 3.35Å; V203-P206 WeakPolarHBondContact O-CD 3.23Å; P206-I210 VanDerWaalsContact O-CB 3.27Å; P206-I210 WeakPolarHBondContact O-CB 3.44Å; P206-I210 WeakPolarHBondContact O-CD1 3.15Å; P206-I210 WeakPolarHBondContact O-CG1 3.33Å; P206-I210 PolarHBondContact O-N 3.46Å
207	F	90.5	Very high	89.1	Confident	49 Å²	49	52.3 Å²	52.3	22%	0.215	27%	0.269	C	S	.	.	H	α-helix	trans	-58.8	-52.8	177.3	169.4	-102	0	0	0	111.3	M38 V42 V203 A204 V211 P220 T223 L224	M38-F207 HydrophobicContact CE-CB 4.06Å; M38-F207 HydrophobicContact CE-CD1 3.54Å; M38-F207 HydrophobicContact CE-CE1 4.13Å; M38-F207 HydrophobicContact CE-CG 3.81Å; V42-F207 HydrophobicContact CG2-CD1 4.02Å; V42-F207 HydrophobicContact CG2-CE1 4.35Å; V203-F207 HydrophobicContact CG1-CB 4.29Å; V203-F207 WeakPolarHBondContact O-CB 3.31Å; V203-F207 PolarHBondContact O-N 2.89Å; A204-F207 PolarHBondContact O-N 3.32Å; F207-V211 HydrophobicContact CD2-CG2 3.97Å; F207-V211 HydrophobicContact CE2-CG2 3.89Å; F207-V211 VanDerWaalsContact O-CB 3.3Å; F207-V211 WeakPolarHBondContact O-CB 3.45Å; F207-V211 VanDerWaalsContact O-CG2 3.23Å; F207-V211 WeakPolarHBondContact O-CG2 3.13Å; F207-V211 PolarHBondContact O-N 3.42Å; F207-P220 HydrophobicContact CE1-CB 4.12Å; F207-T223 HydrophobicContact CZ-CG2 4.13Å; F207-L224 HydrophobicContact CE1-CD1 4.13Å; F207-L224 HydrophobicContact CE1-CD2 4.23Å; F207-L224 HydrophobicContact CE1-CG 4.01Å
208	G	86.6	Confident	89.1	Confident	0 Å²	0	53.8 Å²	53.8	0%	0	28%	0.276	C	S	.	.	H	α-helix	trans	-60.5	-50.1	-179.8	0	0	0	0	0	112.2	A204 Y212	A204-G208 PolarHBondContact O-N 2.79Å; G208-Y212 WeakPolarHBondContact O-CB 3.44Å; G208-Y212 PolarHBondContact O-N 3.49Å
209	G	83.1	Confident	89.2	Confident	23 Å²	23	56.3 Å²	56.3	24%	0.237	29%	0.288	C	S	.	.	H	α-helix	trans	-63.7	-47.4	-178.4	0	0	0	0	0	113.2	P205 Q213	P205-G209 PolarHBondContact O-N 3.03Å; G209-Q213 VanDerWaalsContact O-CB 3.32Å; G209-Q213 WeakPolarHBondContact O-CB 3.37Å; G209-Q213 PolarHBondContact O-N 3.23Å
210	I	88.4	Confident	89.3	Confident	96 Å²	96	51.9 Å²	51.9	49%	0.492	27%	0.268	S	S	.	.	H	α-helix	trans	-65.9	-53	-179.5	-67.1	169.1	0	0	0	110	P206 Y212 Q213 Y214	P206-I210 VanDerWaalsContact O-CB 3.27Å; P206-I210 WeakPolarHBondContact O-CB 3.44Å; P206-I210 WeakPolarHBondContact O-CD1 3.15Å; P206-I210 WeakPolarHBondContact O-CG1 3.33Å; P206-I210 PolarHBondContact O-N 3.46Å; I210-Y212 VanDerWaalsContact C-N 3.31Å; I210-Y212 PolarHBondContact O-N 3.2Å; I210-Q213 PolarHBondContact O-N 3.33Å; I210-Y214 HydrophobicContact CG2-CD2 3.96Å; I210-Y214 HydrophobicContact CG2-CE2 4.01Å; I210-Y214 WeakPolarHBondContact O-CD2 3.06Å; I210-Y214 PolarHBondContact O-N 3.24Å
211	V	91.5	Very high	89.4	Confident	25 Å²	25	52 Å²	52	15%	0.152	27%	0.269	C	S	.	.	H	α-helix	trans	-65.6	-38.3	-176	179.9	0	0	0	0	110.7	F207 Y214 F215 L219 P220	F207-V211 HydrophobicContact CD2-CG2 3.97Å; F207-V211 HydrophobicContact CE2-CG2 3.89Å; F207-V211 VanDerWaalsContact O-CB 3.3Å; F207-V211 WeakPolarHBondContact O-CB 3.45Å; F207-V211 VanDerWaalsContact O-CG2 3.23Å; F207-V211 WeakPolarHBondContact O-CG2 3.13Å; F207-V211 PolarHBondContact O-N 3.42Å; V211-Y214 PolarHBondContact O-N 3.17Å; V211-F215 HydrophobicContact CG1-CB 4.49Å; V211-F215 HydrophobicContact CG1-CD2 4.18Å; V211-F215 WeakPolarHBondContact O-CB 3.29Å; V211-F215 PolarHBondContact O-N 3.1Å; V211-L219 HydrophobicContact CG1-CB 3.99Å; V211-L219 HydrophobicContact CG1-CD2 3.87Å; V211-L219 HydrophobicContact CG1-CG 4Å; V211-P220 HydrophobicContact CB-CG 3.91Å; V211-P220 HydrophobicContact CG1-CB 4.42Å; V211-P220 HydrophobicContact CG1-CG 3.7Å
212	Y	87.8	Confident	89.8	Confident	38 Å²	38	52.2 Å²	52.2	15%	0.149	27%	0.267	C	S	.	.	H	α-helix	trans	-59.6	-45.6	173.5	173.6	-115.6	0	0	0	112.6	I46 D49 G208 I210 Y214 G216 K217	I46-Y212 HydrophobicContact CG1-CD1 4.47Å; I46-Y212 HydrophobicContact CG1-CD2 4.32Å; I46-Y212 HydrophobicContact CG1-CG 3.98Å; I46-Y212 HydrophobicContact CG2-CD2 3.89Å; I46-Y212 HydrophobicContact CG2-CE2 4Å; I46-Y212 HydrophobicContact CG2-CG 4.31Å; D49-Y212 HydrophobicContact CB-CE1 4.14Å; D49-Y212 VanDerWaalsContact OD2-CE1 3.29Å; D49-Y212 WeakPolarHBondContact OD2-CE1 3.43Å; D49-Y212 PolarHBondContact OD2-OH 3.13Å; G208-Y212 WeakPolarHBondContact O-CB 3.44Å; G208-Y212 PolarHBondContact O-N 3.49Å; I210-Y212 VanDerWaalsContact C-N 3.31Å; I210-Y212 PolarHBondContact O-N 3.2Å; Y212-Y214 VanDerWaalsContact C-N 3.3Å; Y212-Y214 PolarHBondContact O-N 2.79Å; Y212-G216 WeakPolarHBondContact CA-O 3.05Å; Y212-G216 WeakPolarHBondContact O-CA 3.44Å; Y212-G216 PolarHBondContact O-N 3.39Å; Y212-K217 HydrophobicContact CD2-CB 4.13Å; Y212-K217 HydrophobicContact CE2-CB 4.04Å
213	Q	86.4	Confident	90.2	Very high	147 Å²	147	52.5 Å²	52.5	69%	0.687	27%	0.27	S	S	*	.	H	α-helix	trans	-61.6	-36.9	-178.2	-175.4	177.4	10.6	0	0	112.7	G209 I210	G209-Q213 VanDerWaalsContact O-CB 3.32Å; G209-Q213 WeakPolarHBondContact O-CB 3.37Å; G209-Q213 PolarHBondContact O-N 3.23Å; I210-Q213 PolarHBondContact O-N 3.33Å
214	Y	90.1	Very high	90.5	Very high	166 Å²	166	50.1 Å²	50.1	65%	0.651	26%	0.256	S	S	*	.	H	α-helix	trans	-93.8	-29.6	-176.9	-69.1	-72	0	0	0	114.2	I210 V211 Y212	I210-Y214 HydrophobicContact CG2-CD2 3.96Å; I210-Y214 HydrophobicContact CG2-CE2 4.01Å; I210-Y214 WeakPolarHBondContact O-CD2 3.06Å; I210-Y214 PolarHBondContact O-N 3.24Å; V211-Y214 PolarHBondContact O-N 3.17Å; Y212-Y214 VanDerWaalsContact C-N 3.3Å; Y212-Y214 PolarHBondContact O-N 2.79Å
215	F	91.3	Very high	90.8	Very high	137 Å²	137	50.1 Å²	50.1	60%	0.601	26%	0.256	S	S	*	.	H	α-helix	trans	-129.1	3.6	-168.4	-59.4	-79.5	0	0	0	114.8	V211 L219	V211-F215 HydrophobicContact CG1-CB 4.49Å; V211-F215 HydrophobicContact CG1-CD2 4.18Å; V211-F215 WeakPolarHBondContact O-CB 3.29Å; V211-F215 PolarHBondContact O-N 3.1Å; F215-L219 HydrophobicContact CB-CB 3.78Å; F215-L219 HydrophobicContact CB-CD2 3.36Å; F215-L219 HydrophobicContact CB-CG 4.19Å; F215-L219 HydrophobicContact CD1-CD2 3.82Å; F215-L219 HydrophobicContact CD2-CD2 3.63Å; F215-L219 HydrophobicContact CE2-CD2 4.35Å; F215-L219 HydrophobicContact CG-CD2 3.32Å
216	G	88.4	Confident	91.3	Very high	26 Å²	26	53.8 Å²	53.8	27%	0.268	27%	0.268	S	S	.	.	T	Hydrogen-bonded Turn	trans	80.5	-179.2	-179.5	0	0	0	0	0	113.7	Y212 E218 P220	Y212-G216 WeakPolarHBondContact CA-O 3.05Å; Y212-G216 WeakPolarHBondContact O-CA 3.44Å; Y212-G216 PolarHBondContact O-N 3.39Å; G216-E218 VanDerWaalsContact C-N 3.26Å; G216-E218 PolarHBondContact O-N 3.31Å; G216-P220 VanDerWaalsContact O-CD 3.22Å; G216-P220 WeakPolarHBondContact O-CD 3.36Å
217	K	87.5	Confident	91.8	Very high	15 Å²	15	54.1 Å²	54.1	7%	0.065	27%	0.266	C	S	.	.	T	Hydrogen-bonded Turn	trans	-68.6	-26.9	-173.4	65.8	159	169.8	55.6	0	112.8	I46 Y50 A146 M154 Y212 P220 F221	I46-K217 HydrophobicContact CG2-CB 4.16Å; Y50-K217 HydrophobicContact CD2-CD 3.85Å; Y50-K217 HydrophobicContact CD2-CG 4.4Å; Y50-K217 HydrophobicContact CE1-CD 4.27Å; Y50-K217 HydrophobicContact CE2-CD 3.45Å; Y50-K217 VanDerWaalsContact CE2-CD 3.45Å; Y50-K217 HydrophobicContact CE2-CG 4.19Å; Y50-K217 HydrophobicContact CG-CD 4.41Å; Y50-K217 WeakPolarHBondContact OH-CE 3.4Å; A146-K217 PolarHBondContact O-NZ 3.34Å; M154-K217 HydrophobicContact CE-CD 4.5Å; Y212-K217 HydrophobicContact CD2-CB 4.13Å; Y212-K217 HydrophobicContact CE2-CB 4.04Å; K217-P220 WeakPolarHBondContact O-CD 3.02Å; K217-F221 WeakPolarHBondContact O-CD2 3.29Å
218	E	92.6	Very high	92.1	Very high	70 Å²	70	51.8 Å²	51.8	33%	0.327	26%	0.255	S	S	.	.	H	α-helix	trans	-67.9	-45.2	-169.7	-66.6	72.1	-162	0	0	110.7	F147 G216 F221 I222	F147-E218 HydrophobicContact CD1-CG 4.41Å; F147-E218 HydrophobicContact CE1-CG 4.41Å; G216-E218 VanDerWaalsContact C-N 3.26Å; G216-E218 PolarHBondContact O-N 3.31Å; E218-F221 PolarHBondContact O-N 3.08Å; E218-I222 HydrophobicContact CB-CD1 3.96Å; E218-I222 WeakPolarHBondContact O-CB 3.38Å; E218-I222 WeakPolarHBondContact O-CG1 3.24Å; E218-I222 PolarHBondContact O-N 2.82Å
219	L	94.2	Very high	92.5	Very high	65 Å²	65	54 Å²	54	34%	0.34	27%	0.267	S	S	.	.	H	α-helix	trans	-67.1	-43.1	-168.6	-165.8	68.9	0	0	0	114.5	V211 F215 F221 T223	V211-L219 HydrophobicContact CG1-CB 3.99Å; V211-L219 HydrophobicContact CG1-CD2 3.87Å; V211-L219 HydrophobicContact CG1-CG 4Å; F215-L219 HydrophobicContact CB-CB 3.78Å; F215-L219 HydrophobicContact CB-CD2 3.36Å; F215-L219 HydrophobicContact CB-CG 4.19Å; F215-L219 HydrophobicContact CD1-CD2 3.82Å; F215-L219 HydrophobicContact CD2-CD2 3.63Å; F215-L219 HydrophobicContact CE2-CD2 4.35Å; F215-L219 HydrophobicContact CG-CD2 3.32Å; L219-F221 VanDerWaalsContact C-N 3.34Å; L219-F221 PolarHBondContact O-N 3.19Å; L219-T223 VanDerWaalsContact O-CB 3.29Å; L219-T223 WeakPolarHBondContact O-CB 3.3Å; L219-T223 PolarHBondContact O-N 3.34Å; L219-T223 PolarHBondContact O-OG1 3.21Å
220	P	93.5	Very high	93.2	Very high	0 Å²	0	59.8 Å²	59.8	0%	0	29%	0.286	C	S	.	.	H	α-helix	trans	-56.4	-46.9	175.5	-21.2	28.8	0	0	0	112.4	V42 I46 F207 V211 G216 K217 L224	V42-P220 HydrophobicContact CG2-CB 4.28Å; I46-P220 HydrophobicContact CD1-CB 4.04Å; I46-P220 HydrophobicContact CD1-CG 3.94Å; F207-P220 HydrophobicContact CE1-CB 4.12Å; V211-P220 HydrophobicContact CB-CG 3.91Å; V211-P220 HydrophobicContact CG1-CB 4.42Å; V211-P220 HydrophobicContact CG1-CG 3.7Å; G216-P220 VanDerWaalsContact O-CD 3.22Å; G216-P220 WeakPolarHBondContact O-CD 3.36Å; K217-P220 WeakPolarHBondContact O-CD 3.02Å; P220-L224 WeakPolarHBondContact O-CG 3.47Å; P220-L224 PolarHBondContact O-N 3.13Å; P220-L224 VanDerWaalsContact O-N 3.17Å
221	F	95	Very high	93.6	Very high	1 Å²	1	55.4 Å²	55.4	0%	0.004	26%	0.263	C	S	.	.	H	α-helix	trans	-73.4	-43	-177.5	-67.7	-64.9	0	0	0	112.3	L39 V42 I43 I46 T142 F145 A146 K217 E218 L219 T223 L224 A225	L39-F221 HydrophobicContact CD2-CD1 4.28Å; V42-F221 HydrophobicContact CG1-CD1 4.24Å; V42-F221 HydrophobicContact CG1-CE1 3.5Å; V42-F221 HydrophobicContact CG1-CZ 4.05Å; I43-F221 HydrophobicContact CG2-CE1 3.66Å; I43-F221 HydrophobicContact CG2-CZ 3.65Å; I46-F221 HydrophobicContact CD1-CE2 3.84Å; I46-F221 HydrophobicContact CD1-CZ 4.02Å; I46-F221 HydrophobicContact CG2-CE2 4.27Å; T142-F221 HydrophobicContact CG2-CB 3.83Å; T142-F221 HydrophobicContact CG2-CD1 4.1Å; T142-F221 HydrophobicContact CG2-CG 4.44Å; T142-F221 WeakPolarHBondContact CG2-O 3.34Å; F145-F221 AromaticContact CD1-CD1 3.91Å; F145-F221 HydrophobicContact CD1-CD1 3.91Å; F145-F221 AromaticContact CD1-CD2 3.8Å; F145-F221 HydrophobicContact CD1-CD2 3.8Å; F145-F221 AromaticContact CD1-CE1 3.66Å; F145-F221 HydrophobicContact CD1-CE1 3.66Å; F145-F221 AromaticContact CD1-CE2 3.6Å; F145-F221 HydrophobicContact CD1-CE2 3.6Å; F145-F221 HydrophobicContact CD1-CG 4Å; F145-F221 AromaticContact CD1-CZ 3.54Å; F145-F221 HydrophobicContact CD1-CZ 3.54Å; F145-F221 HydrophobicContact CE1-CD1 4.46Å; F145-F221 HydrophobicContact CE1-CD2 4.24Å; F145-F221 AromaticContact CE1-CE1 3.77Å; F145-F221 HydrophobicContact CE1-CE1 3.77Å; F145-F221 AromaticContact CE1-CE2 3.55Å; F145-F221 HydrophobicContact CE1-CE2 3.55Å; F145-F221 AromaticContact CE1-CZ 3.29Å; F145-F221 HydrophobicContact CE1-CZ 3.29Å; F145-F221 HydrophobicContact CZ-CZ 4.39Å; A146-F221 HydrophobicContact CB-CB 3.65Å; K217-F221 WeakPolarHBondContact O-CD2 3.29Å; E218-F221 PolarHBondContact O-N 3.08Å; L219-F221 VanDerWaalsContact C-N 3.34Å; L219-F221 PolarHBondContact O-N 3.19Å; F221-T223 VanDerWaalsContact C-N 3.27Å; F221-T223 PolarHBondContact O-N 3.49Å; F221-L224 PolarHBondContact O-N 2.84Å; F221-A225 WeakPolarHBondContact O-CB 3.41Å; F221-A225 PolarHBondContact O-N 3.31Å
222	I	95.9	Very high	93.9	Very high	39 Å²	39	54.2 Å²	54.2	20%	0.2	26%	0.256	C	S	.	.	H	α-helix	trans	-59.1	-42.7	175.6	-71	169.3	0	0	0	110.3	A146 F147 E218 A225 F226	A146-I222 HydrophobicContact CB-CG1 3.87Å; F147-I222 HydrophobicContact CE1-CD1 4.02Å; F147-I222 HydrophobicContact CE2-CD1 4.22Å; F147-I222 HydrophobicContact CE2-CG1 4.43Å; F147-I222 HydrophobicContact CZ-CD1 3.52Å; F147-I222 HydrophobicContact CZ-CG1 4.2Å; E218-I222 HydrophobicContact CB-CD1 3.96Å; E218-I222 WeakPolarHBondContact O-CB 3.38Å; E218-I222 WeakPolarHBondContact O-CG1 3.24Å; E218-I222 PolarHBondContact O-N 2.82Å; I222-A225 WeakPolarHBondContact O-CB 3.43Å; I222-A225 PolarHBondContact O-N 3.05Å; I222-F226 HydrophobicContact CG2-CD2 3.67Å; I222-F226 HydrophobicContact CG2-CE2 3.75Å; I222-F226 WeakPolarHBondContact O-CD2 3.46Å; I222-F226 PolarHBondContact O-N 3.19Å
223	T	96.4	Very high	94.2	Very high	50 Å²	50	55.2 Å²	55.2	31%	0.307	27%	0.268	S	S	.	.	H	α-helix	trans	-58.8	-51.8	177.6	-58	0	0	0	0	110.7	F207 L219 F221 A225 F226 I227	F207-T223 HydrophobicContact CZ-CG2 4.13Å; L219-T223 VanDerWaalsContact O-CB 3.29Å; L219-T223 WeakPolarHBondContact O-CB 3.3Å; L219-T223 PolarHBondContact O-N 3.34Å; L219-T223 PolarHBondContact O-OG1 3.21Å; F221-T223 VanDerWaalsContact C-N 3.27Å; F221-T223 PolarHBondContact O-N 3.49Å; T223-A225 VanDerWaalsContact C-N 3.32Å; T223-A225 PolarHBondContact O-N 2.99Å; T223-F226 PolarHBondContact O-N 3.35Å; T223-I227 HydrophobicContact CG2-CD1 4.02Å; T223-I227 VanDerWaalsContact O-CG1 3.28Å; T223-I227 WeakPolarHBondContact O-CG1 3.44Å; T223-I227 PolarHBondContact O-N 3.4Å
224	L	96.2	Very high	94.7	Very high	1 Å²	1	49.8 Å²	49.8	1%	0.005	24%	0.244	C	C	.	.	H	α-helix	trans	-62.8	-37.7	178.7	-67.3	173.6	0	0	0	112.6	L35 M38 L39 V42 F207 P220 F221 I227 A228	L35-L224 HydrophobicContact CD2-CD2 3.79Å; M38-L224 HydrophobicContact CB-CD1 4.32Å; M38-L224 HydrophobicContact CB-CD2 4.05Å; M38-L224 HydrophobicContact CE-CD2 3.97Å; M38-L224 HydrophobicContact SD-CD2 3.94Å; L39-L224 HydrophobicContact CD2-CB 3.86Å; L39-L224 HydrophobicContact CD2-CD1 3.67Å; L39-L224 HydrophobicContact CD2-CG 4.41Å; L39-L224 HydrophobicContact CG-CB 4.4Å; L39-L224 HydrophobicContact CG-CD1 4.14Å; V42-L224 HydrophobicContact CB-CD1 4.38Å; V42-L224 HydrophobicContact CG1-CD1 4.01Å; V42-L224 HydrophobicContact CG2-CD1 4.43Å; F207-L224 HydrophobicContact CE1-CD1 4.13Å; F207-L224 HydrophobicContact CE1-CD2 4.23Å; F207-L224 HydrophobicContact CE1-CG 4.01Å; P220-L224 WeakPolarHBondContact O-CG 3.47Å; P220-L224 PolarHBondContact O-N 3.13Å; P220-L224 VanDerWaalsContact O-N 3.17Å; F221-L224 PolarHBondContact O-N 2.84Å; L224-I227 PolarHBondContact O-N 3.02Å; L224-A228 PolarHBondContact O-N 3.17Å
225	A	97.1	Very high	94.9	Very high	0 Å²	0	41.9 Å²	41.9	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-59.8	-49.2	176.1	0	0	0	0	0	111.3	F139 T142 F221 I222 T223 I227 A228 L229	F139-A225 HydrophobicContact CD2-CB 3.78Å; F139-A225 WeakPolarHBondContact CD2-O 3.28Å; F139-A225 HydrophobicContact CE2-CB 4.33Å; T142-A225 HydrophobicContact CG2-CB 3.9Å; F221-A225 WeakPolarHBondContact O-CB 3.41Å; F221-A225 PolarHBondContact O-N 3.31Å; I222-A225 WeakPolarHBondContact O-CB 3.43Å; I222-A225 PolarHBondContact O-N 3.05Å; T223-A225 VanDerWaalsContact C-N 3.32Å; T223-A225 PolarHBondContact O-N 2.99Å; A225-I227 VanDerWaalsContact C-N 3.35Å; A225-I227 PolarHBondContact O-N 3.44Å; A225-A228 WeakPolarHBondContact O-CB 3.39Å; A225-A228 PolarHBondContact O-N 3.39Å; A225-L229 PolarHBondContact O-N 3.16Å
226	F	97.2	Very high	95	Very high	121 Å²	121	37.8 Å²	37.8	53%	0.531	20%	0.197	S	C	.	.	H	α-helix	trans	-67.8	-32.8	179.6	-85.3	-76.7	0	0	0	113	F139 I222 T223 A228 L229 F230	F139-F226 HydrophobicContact CE2-CD1 4.43Å; F139-F226 HydrophobicContact CE2-CE1 4.33Å; F139-F226 HydrophobicContact CE2-CZ 4.39Å; I222-F226 HydrophobicContact CG2-CD2 3.67Å; I222-F226 HydrophobicContact CG2-CE2 3.75Å; I222-F226 WeakPolarHBondContact O-CD2 3.46Å; I222-F226 PolarHBondContact O-N 3.19Å; T223-F226 PolarHBondContact O-N 3.35Å; F226-A228 VanDerWaalsContact C-N 3.35Å; F226-L229 PolarHBondContact O-N 3.46Å; F226-F230 WeakPolarHBondContact O-CB 3.45Å; F226-F230 PolarHBondContact O-N 2.8Å
227	I	97	Very high	95.3	Very high	68 Å²	68	39.6 Å²	39.6	35%	0.349	20%	0.2	S	C	.	.	H	α-helix	trans	-64.9	-42.2	172.7	-58	164.7	0	0	0	109.8	I31 L35 T223 L224 A225 L229 F230 D231	I31-I227 HydrophobicContact CG2-CG2 4.2Å; L35-I227 HydrophobicContact CD1-CB 4.3Å; L35-I227 HydrophobicContact CD1-CG2 3.87Å; L35-I227 HydrophobicContact CD2-CB 3.81Å; L35-I227 HydrophobicContact CD2-CD1 4.4Å; L35-I227 HydrophobicContact CD2-CG2 3.75Å; L35-I227 HydrophobicContact CG-CG2 4.24Å; T223-I227 HydrophobicContact CG2-CD1 4.02Å; T223-I227 VanDerWaalsContact O-CG1 3.28Å; T223-I227 WeakPolarHBondContact O-CG1 3.44Å; T223-I227 PolarHBondContact O-N 3.4Å; L224-I227 PolarHBondContact O-N 3.02Å; A225-I227 VanDerWaalsContact C-N 3.35Å; A225-I227 PolarHBondContact O-N 3.44Å; I227-L229 VanDerWaalsContact C-N 3.35Å; I227-L229 PolarHBondContact O-N 3.29Å; I227-F230 PolarHBondContact O-N 3.45Å; I227-D231 VanDerWaalsContact O-CB 3.29Å; I227-D231 WeakPolarHBondContact O-CB 3.37Å; I227-D231 PolarHBondContact O-N 3.34Å
228	A	97	Very high	95.6	Very high	0 Å²	0	39 Å²	39	0%	0	20%	0.197	C	C	.	.	H	α-helix	trans	-60.9	-41.9	175.4	0	0	0	0	0	112.5	L35 L135 I138 L224 A225 F226 D231 G232	L35-A228 HydrophobicContact CD1-CB 4.04Å; L135-A228 HydrophobicContact CD2-CB 4.28Å; I138-A228 HydrophobicContact CG2-CB 4.06Å; L224-A228 PolarHBondContact O-N 3.17Å; A225-A228 WeakPolarHBondContact O-CB 3.39Å; A225-A228 PolarHBondContact O-N 3.39Å; F226-A228 VanDerWaalsContact C-N 3.35Å; A228-D231 PolarHBondContact O-N 3.23Å; A228-G232 PolarHBondContact O-N 2.94Å
229	L	96.8	Very high	95.7	Very high	47 Å²	47	35.7 Å²	35.7	25%	0.246	18%	0.182	C	C	.	.	H	α-helix	trans	-65.7	-43.1	176.3	-176.6	62.9	0	0	0	111.9	M132 F139 A225 F226 I227 G232 C233	M132-L229 HydrophobicContact CE-CD1 4.37Å; F139-L229 HydrophobicContact CB-CB 4.38Å; F139-L229 HydrophobicContact CD2-CB 3.94Å; F139-L229 HydrophobicContact CD2-CD2 4.2Å; F139-L229 HydrophobicContact CE1-CD2 4.39Å; F139-L229 HydrophobicContact CE2-CB 4.5Å; F139-L229 HydrophobicContact CE2-CD2 4.01Å; F139-L229 HydrophobicContact CG-CB 4.16Å; F139-L229 HydrophobicContact CG-CD2 4.48Å; F139-L229 HydrophobicContact CZ-CD2 4.11Å; A225-L229 PolarHBondContact O-N 3.16Å; F226-L229 PolarHBondContact O-N 3.46Å; I227-L229 VanDerWaalsContact C-N 3.35Å; I227-L229 PolarHBondContact O-N 3.29Å; L229-G232 PolarHBondContact O-N 3.11Å; L229-C233 PolarHBondContact O-N 2.92Å; L229-C233 PolarHBondContact O-SG 2.58Å; L229-C233 VanDerWaalsContact O-SG 3.39Å
230	F	97.4	Very high	95.6	Very high	143 Å²	143	36.7 Å²	36.7	63%	0.627	19%	0.185	S	C	*	.	H	α-helix	trans	-63.4	-44	177	179	-98	0	0	0	111.7	F226 I227 G232 C233 L234	F226-F230 WeakPolarHBondContact O-CB 3.45Å; F226-F230 PolarHBondContact O-N 2.8Å; I227-F230 PolarHBondContact O-N 3.45Å; F230-G232 VanDerWaalsContact C-N 3.33Å; F230-G232 PolarHBondContact O-N 3.08Å; F230-C233 PolarHBondContact O-N 2.9Å; F230-L234 HydrophobicContact CE1-CD2 4.3Å; F230-L234 WeakPolarHBondContact O-CB 3.49Å; F230-L234 PolarHBondContact O-N 3.25Å
231	D	97.1	Very high	95.5	Very high	4 Å²	4	38 Å²	38	2%	0.021	19%	0.194	C	C	.	.	H	α-helix	trans	-60.5	-42.9	176.8	-169.2	56.6	0	0	0	111.5	V28 I31 A32 I227 A228 L234 L235	V28-D231 WeakPolarHBondContact CG1-OD1 3.4Å; I31-D231 HydrophobicContact CG2-CB 4.09Å; A32-D231 WeakPolarHBondContact CB-OD2 3.31Å; A32-D231 PolarHBondContact N-OD2 3.35Å; I227-D231 VanDerWaalsContact O-CB 3.29Å; I227-D231 WeakPolarHBondContact O-CB 3.37Å; I227-D231 PolarHBondContact O-N 3.34Å; A228-D231 PolarHBondContact O-N 3.23Å; D231-L234 PolarHBondContact O-N 2.81Å; D231-L235 WeakPolarHBondContact O-CB 3.29Å; D231-L235 PolarHBondContact O-N 3.46Å
232	G	96.4	Very high	95.3	Very high	0 Å²	0	38.6 Å²	38.6	0%	0	20%	0.197	C	C	.	.	H	α-helix	trans	-63.4	-42.8	174.2	0	0	0	0	0	113.5	M132 L135 A228 L229 F230 L234 L235 L236	M132-G232 WeakPolarHBondContact SD-CA 3.1Å; M132-G232 VanDerWaalsContact SD-O 3.34Å; L135-G232 VanDerWaalsContact CD1-CA 3.49Å; A228-G232 PolarHBondContact O-N 2.94Å; L229-G232 PolarHBondContact O-N 3.11Å; F230-G232 VanDerWaalsContact C-N 3.33Å; F230-G232 PolarHBondContact O-N 3.08Å; G232-L234 VanDerWaalsContact C-N 3.34Å; G232-L234 PolarHBondContact O-N 3.3Å; G232-L235 WeakPolarHBondContact O-CB 3.42Å; G232-L235 PolarHBondContact O-N 3.43Å; G232-L236 WeakPolarHBondContact O-CG 3.16Å; G232-L236 PolarHBondContact O-N 3.02Å
233	C	95.4	Very high	95.2	Very high	60 Å²	60	40.2 Å²	40.2	41%	0.405	20%	0.201	S	C	.	.	H	α-helix	trans	-62.4	-42.2	174.2	-74	0	0	0	0	111.9	L229 F230 L236 I237	L229-C233 PolarHBondContact O-N 2.92Å; L229-C233 PolarHBondContact O-SG 2.58Å; L229-C233 VanDerWaalsContact O-SG 3.39Å; F230-C233 PolarHBondContact O-N 2.9Å; C233-L236 PolarHBondContact O-N 3.27Å; C233-I237 WeakPolarHBondContact O-CG1 3.38Å; C233-I237 PolarHBondContact O-N 2.95Å
234	L	95.6	Very high	95	Very high	33 Å²	33	43.2 Å²	43.2	17%	0.173	21%	0.213	C	C	.	.	H	α-helix	trans	-63.9	-43.5	177.3	-179.9	58	0	0	0	111.2	F11 V28 F230 D231 G232 L236 I237 I238	F11-L234 HydrophobicContact CZ-CD1 3.93Å; V28-L234 HydrophobicContact CG2-CD2 3.91Å; V28-L234 HydrophobicContact CG2-CG 3.91Å; F230-L234 HydrophobicContact CE1-CD2 4.3Å; F230-L234 WeakPolarHBondContact O-CB 3.49Å; F230-L234 PolarHBondContact O-N 3.25Å; D231-L234 PolarHBondContact O-N 2.81Å; G232-L234 VanDerWaalsContact C-N 3.34Å; G232-L234 PolarHBondContact O-N 3.3Å; L234-L236 VanDerWaalsContact C-N 3.29Å; L234-L236 PolarHBondContact O-N 3.43Å; L234-I237 PolarHBondContact O-N 3.4Å; L234-I238 HydrophobicContact CD1-CD1 3.73Å; L234-I238 HydrophobicContact CD1-CG1 4.27Å; L234-I238 HydrophobicContact CD2-CD1 4.44Å; L234-I238 HydrophobicContact CG-CD1 3.67Å; L234-I238 WeakPolarHBondContact O-CG1 3.28Å; L234-I238 PolarHBondContact O-N 2.96Å
235	L	95.8	Very high	94.7	Very high	0 Å²	0	45.4 Å²	45.4	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-54	-47.2	172.4	-178.8	70.1	0	0	0	111.2	V28 D128 M131 M175 D231 G232 I237 I238 M239	V28-L235 HydrophobicContact CG1-CB 3.75Å; V28-L235 HydrophobicContact CG1-CD1 3.69Å; V28-L235 HydrophobicContact CG1-CG 4.27Å; D128-L235 HydrophobicContact CB-CD2 4.31Å; D128-L235 HydrophobicContact CB-CG 4.38Å; M131-L235 HydrophobicContact CB-CD2 3.65Å; M131-L235 HydrophobicContact CE-CD2 4.19Å; M131-L235 HydrophobicContact CG-CD2 3.56Å; M131-L235 HydrophobicContact SD-CD1 3.96Å; M131-L235 HydrophobicContact SD-CD2 3.45Å; M131-L235 WeakPolarHBondContact SD-CD2 3.11Å; M131-L235 HydrophobicContact SD-CG 4.33Å; M175-L235 HydrophobicContact CE-CD1 3.81Å; M175-L235 HydrophobicContact CE-CD2 4.43Å; M175-L235 HydrophobicContact SD-CD1 3.82Å; D231-L235 WeakPolarHBondContact O-CB 3.29Å; D231-L235 PolarHBondContact O-N 3.46Å; G232-L235 WeakPolarHBondContact O-CB 3.42Å; G232-L235 PolarHBondContact O-N 3.43Å; L235-I237 PolarHBondContact O-N 3.24Å; L235-I238 PolarHBondContact O-N 3.17Å; L235-M239 HydrophobicContact CD1-CG 3.74Å; L235-M239 HydrophobicContact CG-CG 4.23Å; L235-M239 WeakPolarHBondContact O-CB 3.48Å; L235-M239 WeakPolarHBondContact O-CG 3.15Å; L235-M239 PolarHBondContact O-N 3.03Å
236	L	93.5	Very high	94.5	Very high	51 Å²	51	47.6 Å²	47.6	27%	0.267	23%	0.232	S	C	.	.	H	α-helix	trans	-62.1	-32.8	-176.1	-75.4	-177.9	0	0	0	112.4	M132 G232 C233 L234 Q240 R243	M132-L236 HydrophobicContact CB-CD2 4.01Å; M132-L236 HydrophobicContact CB-CG 4.32Å; M132-L236 HydrophobicContact CE-CD1 4.29Å; M132-L236 HydrophobicContact CG-CD1 3.92Å; M132-L236 HydrophobicContact CG-CD2 4.09Å; M132-L236 HydrophobicContact CG-CG 4.02Å; M132-L236 HydrophobicContact SD-CD1 3.92Å; M132-L236 HydrophobicContact SD-CG 3.99Å; G232-L236 WeakPolarHBondContact O-CG 3.16Å; G232-L236 PolarHBondContact O-N 3.02Å; C233-L236 PolarHBondContact O-N 3.27Å; L234-L236 VanDerWaalsContact C-N 3.29Å; L234-L236 PolarHBondContact O-N 3.43Å; L236-Q240 WeakPolarHBondContact O-CG 3.45Å; L236-R243 VanDerWaalsContact CD2-NH2 3.26Å; L236-R243 PolarHBondContact O-NH2 3.49Å
237	I	93.2	Very high	94.3	Very high	63 Å²	63	45.9 Å²	45.9	32%	0.323	23%	0.231	S	C	.	.	H	α-helix	trans	-76.9	-45	178.3	-60.1	165.7	0	0	0	110.4	F11 M12 I15 C233 L234 L235 M239 Q240	F11-I237 HydrophobicContact CD1-CG2 4.48Å; F11-I237 HydrophobicContact CE1-CG2 3.75Å; M12-I237 HydrophobicContact CE-CG2 3.88Å; I15-I237 HydrophobicContact CD1-CG2 3.85Å; C233-I237 WeakPolarHBondContact O-CG1 3.38Å; C233-I237 PolarHBondContact O-N 2.95Å; L234-I237 PolarHBondContact O-N 3.4Å; L235-I237 PolarHBondContact O-N 3.24Å; I237-M239 VanDerWaalsContact C-N 3.32Å; I237-M239 PolarHBondContact O-N 3.2Å; I237-Q240 WeakPolarHBondContact O-CG 3.37Å; I237-Q240 PolarHBondContact O-N 3.38Å
238	I	94.6	Very high	94.1	Very high	2 Å²	2	45 Å²	45	1%	0.01	23%	0.229	C	C	.	.	H	α-helix	trans	-65.2	-35.7	-178.2	-69.4	162	0	0	0	111.9	F11 I15 Q21 M24 V25 V28 L234 L235 Q240 P241	F11-I238 HydrophobicContact CZ-CG1 4.49Å; I15-I238 HydrophobicContact CD1-CG1 4.3Å; I15-I238 HydrophobicContact CG1-CG1 4.39Å; Q21-I238 HydrophobicContact CG-CG2 4.29Å; M24-I238 HydrophobicContact CB-CD1 3.93Å; M24-I238 HydrophobicContact CB-CG1 4.33Å; M24-I238 HydrophobicContact CB-CG2 4.04Å; M24-I238 HydrophobicContact CE-CD1 4.01Å; M24-I238 HydrophobicContact CE-CG1 3.83Å; V25-I238 HydrophobicContact CG2-CG2 3.72Å; V28-I238 HydrophobicContact CG2-CD1 3.59Å; L234-I238 HydrophobicContact CD1-CD1 3.73Å; L234-I238 HydrophobicContact CD1-CG1 4.27Å; L234-I238 HydrophobicContact CD2-CD1 4.44Å; L234-I238 HydrophobicContact CG-CD1 3.67Å; L234-I238 WeakPolarHBondContact O-CG1 3.28Å; L234-I238 PolarHBondContact O-N 2.96Å; L235-I238 PolarHBondContact O-N 3.17Å; I238-Q240 VanDerWaalsContact C-N 3.32Å; I238-Q240 PolarHBondContact O-N 3.34Å; I238-P241 VanDerWaalsContact O-CD 3.26Å; I238-P241 WeakPolarHBondContact O-CD 3.42Å
239	M	94.1	Very high	93.9	Very high	1 Å²	1	47 Å²	47	1%	0.005	24%	0.24	C	C	.	.	T	Hydrogen-bonded Turn	trans	-85.2	2.2	-174.9	-70.4	-65.3	-70.4	0	0	114.7	V25 D128 M175 L235 I237 P241 V242 R243	V25-M239 HydrophobicContact CG2-SD 3.64Å; D128-M239 HydrophobicContact CB-CB 3.73Å; D128-M239 HydrophobicContact CB-CE 3.99Å; D128-M239 HydrophobicContact CB-CG 3.7Å; D128-M239 WeakPolarHBondContact OD2-CB 3.42Å; M175-M239 HydrophobicContact CE-CE 4.27Å; M175-M239 HydrophobicContact CG-CE 3.95Å; M175-M239 HydrophobicContact CG-SD 4.28Å; M175-M239 HydrophobicContact SD-CE 3.71Å; M175-M239 HydrophobicContact SD-CG 4.07Å; M175-M239 HydrophobicContact SD-SD 3.57Å; L235-M239 HydrophobicContact CD1-CG 3.74Å; L235-M239 HydrophobicContact CG-CG 4.23Å; L235-M239 WeakPolarHBondContact O-CB 3.48Å; L235-M239 WeakPolarHBondContact O-CG 3.15Å; L235-M239 PolarHBondContact O-N 3.03Å; I237-M239 VanDerWaalsContact C-N 3.32Å; I237-M239 PolarHBondContact O-N 3.2Å; M239-P241 VanDerWaalsContact C-CD 3.46Å; M239-V242 HydrophobicContact CE-CB 3.78Å; M239-V242 HydrophobicContact CE-CG1 3.74Å; M239-V242 HydrophobicContact CE-CG2 4Å; M239-V242 PolarHBondContact O-N 2.88Å; M239-V242 HydrophobicContact SD-CB 4.31Å; M239-V242 HydrophobicContact SD-CG2 3.94Å; M239-R243 PolarHBondContact O-N 3.3Å
240	Q	92.8	Very high	93.7	Very high	86 Å²	86	52 Å²	52	40%	0.402	26%	0.259	S	S	.	.	H	α-helix	trans	-53.3	-47.2	178	-70.7	-177.5	-16	0	0	114.2	L236 I237 I238 V242 R243 I244	L236-Q240 WeakPolarHBondContact O-CG 3.45Å; I237-Q240 WeakPolarHBondContact O-CG 3.37Å; I237-Q240 PolarHBondContact O-N 3.38Å; I238-Q240 VanDerWaalsContact C-N 3.32Å; I238-Q240 PolarHBondContact O-N 3.34Å; Q240-V242 VanDerWaalsContact C-N 3.29Å; Q240-V242 PolarHBondContact O-N 3.48Å; Q240-R243 WeakPolarHBondContact O-CB 3.41Å; Q240-R243 PolarHBondContact O-N 2.84Å; Q240-I244 WeakPolarHBondContact O-CG1 3.46Å; Q240-I244 PolarHBondContact O-N 2.99Å; Q240-I244 VanDerWaalsContact O-N 3.09Å
241	P	91.1	Very high	93.5	Very high	29 Å²	29	51 Å²	51	19%	0.188	27%	0.265	C	S	.	.	H	α-helix	trans	-64.4	-38.4	-178.9	-15.9	29.7	0	0	0	111.6	I15 I238 M239 I244 E245	I15-P241 HydrophobicContact CG2-CG 3.4Å; I15-P241 VanDerWaalsContact CG2-CG 3.4Å; I238-P241 VanDerWaalsContact O-CD 3.26Å; I238-P241 WeakPolarHBondContact O-CD 3.42Å; M239-P241 VanDerWaalsContact C-CD 3.46Å; P241-I244 PolarHBondContact O-N 2.95Å; P241-E245 WeakPolarHBondContact O-CB 3.41Å; P241-E245 PolarHBondContact O-N 2.95Å
242	V	91.8	Very high	93.3	Very high	12 Å²	12	56.3 Å²	56.3	7%	0.073	29%	0.29	C	S	.	.	H	α-helix	trans	-67.7	-38.4	-179.9	-171	0	0	0	0	111.1	M239 Q240 I244 E245 R246	M239-V242 HydrophobicContact CE-CB 3.78Å; M239-V242 HydrophobicContact CE-CG1 3.74Å; M239-V242 HydrophobicContact CE-CG2 4Å; M239-V242 PolarHBondContact O-N 2.88Å; M239-V242 HydrophobicContact SD-CB 4.31Å; M239-V242 HydrophobicContact SD-CG2 3.94Å; Q240-V242 VanDerWaalsContact C-N 3.29Å; Q240-V242 PolarHBondContact O-N 3.48Å; V242-I244 VanDerWaalsContact C-N 3.35Å; V242-E245 PolarHBondContact O-N 2.94Å; V242-R246 WeakPolarHBondContact O-CB 3.41Å; V242-R246 PolarHBondContact O-N 3.16Å
243	R	92.1	Very high	93.1	Very high	74 Å²	74	59.3 Å²	59.3	28%	0.279	32%	0.321	S	S	.	.	H	α-helix	trans	-61.3	-43.2	172.3	-100.4	-177.2	-100.8	169	-8.3	112.2	D128 L236 M239 Q240 T247	D128-R243 IonicContact OD2-CZ 3.11Å; D128-R243 IonicContact OD2-NE 2.58Å; D128-R243 PolarHBondContact OD2-NE 3.27Å; D128-R243 IonicContact OD2-NH2 2.8Å; D128-R243 PolarHBondContact OD2-NH2 3.37Å; L236-R243 VanDerWaalsContact CD2-NH2 3.26Å; L236-R243 PolarHBondContact O-NH2 3.49Å; M239-R243 PolarHBondContact O-N 3.3Å; Q240-R243 WeakPolarHBondContact O-CB 3.41Å; Q240-R243 PolarHBondContact O-N 2.84Å; R243-T247 WeakPolarHBondContact O-CB 3.2Å; R243-T247 PolarHBondContact O-N 3.47Å; R243-T247 PolarHBondContact O-OG1 3.26Å
244	I	92.6	Very high	92.9	Very high	112 Å²	112	61.5 Å²	61.5	57%	0.574	33%	0.329	S	S	*	.	H	α-helix	trans	-63.9	-50.7	178.2	-66.4	166.3	0	0	0	109.5	Q240 P241 V242 R246 T247 V248	Q240-I244 WeakPolarHBondContact O-CG1 3.46Å; Q240-I244 PolarHBondContact O-N 2.99Å; Q240-I244 VanDerWaalsContact O-N 3.09Å; P241-I244 PolarHBondContact O-N 2.95Å; V242-I244 VanDerWaalsContact C-N 3.35Å; I244-R246 VanDerWaalsContact C-N 3.34Å; I244-R246 PolarHBondContact O-N 3.09Å; I244-T247 WeakPolarHBondContact O-CB 3.31Å; I244-T247 PolarHBondContact O-N 3.44Å; I244-V248 WeakPolarHBondContact O-CG2 3.28Å; I244-V248 PolarHBondContact O-N 2.9Å
245	E	91.2	Very high	92.7	Very high	47 Å²	47	61.9 Å²	61.9	22%	0.22	33%	0.331	C	S	.	.	H	α-helix	trans	-53.4	-49	176.5	-175.4	-173.6	178.8	0	0	111.7	R179 P241 V242 T247 V248 L249 I462	R179-E245 IonicContact NH1-OE2 3.8Å; P241-E245 WeakPolarHBondContact O-CB 3.41Å; P241-E245 PolarHBondContact O-N 2.95Å; V242-E245 PolarHBondContact O-N 2.94Å; E245-T247 VanDerWaalsContact C-N 3.32Å; E245-T247 PolarHBondContact O-N 3.09Å; E245-V248 PolarHBondContact O-N 3.5Å; E245-L249 WeakPolarHBondContact O-CG 3.33Å; E245-L249 PolarHBondContact O-N 3.45Å; E245-I462 VanDerWaalsContact OE1-CG2 3.31Å; E245-I462 WeakPolarHBondContact OE1-CG2 3.31Å
246	R	92.2	Very high	92.3	Very high	46 Å²	46	63.9 Å²	63.9	17%	0.174	34%	0.344	C	S	.	.	H	α-helix	trans	-62.4	-38.1	177.5	-169.1	-179.2	176.6	108.9	-0.7	112.5	D123 R124 G126 V242 I244 L249 K250 L255	D123-R246 PolarHBondContact O-NH2 2.73Å; R124-R246 PolarHBondContact O-NH2 2.99Å; G126-R246 VanDerWaalsContact N-CZ 3.34Å; G126-R246 VanDerWaalsContact N-NH2 3.16Å; V242-R246 WeakPolarHBondContact O-CB 3.41Å; V242-R246 PolarHBondContact O-N 3.16Å; I244-R246 VanDerWaalsContact C-N 3.34Å; I244-R246 PolarHBondContact O-N 3.09Å; R246-L249 PolarHBondContact O-N 3.43Å; R246-K250 WeakPolarHBondContact O-CB 3.48Å; R246-K250 PolarHBondContact O-N 2.93Å; R246-L255 HydrophobicContact CG-CD1 3.64Å
247	T	92.6	Very high	92.2	Very high	85 Å²	85	70.4 Å²	70.4	52%	0.521	37%	0.37	S	S	.	.	H	α-helix	trans	-65.9	-43.4	178	-58.6	0	0	0	0	110.8	R243 I244 E245 K250 T251	R243-T247 WeakPolarHBondContact O-CB 3.2Å; R243-T247 PolarHBondContact O-N 3.47Å; R243-T247 PolarHBondContact O-OG1 3.26Å; I244-T247 WeakPolarHBondContact O-CB 3.31Å; I244-T247 PolarHBondContact O-N 3.44Å; E245-T247 VanDerWaalsContact C-N 3.32Å; E245-T247 PolarHBondContact O-N 3.09Å; T247-K250 WeakPolarHBondContact O-CB 3.15Å; T247-K250 PolarHBondContact O-N 2.87Å; T247-T251 PolarHBondContact O-N 3.49Å; T247-T251 PolarHBondContact O-OG1 3.08Å; T247-T251 VanDerWaalsContact O-OG1 3.11Å
248	V	94.1	Very high	92.1	Very high	50 Å²	50	68.5 Å²	68.5	30%	0.303	37%	0.366	S	S	.	.	H	α-helix	trans	-60.2	-48.7	174.9	173.6	0	0	0	0	110.8	I244 E245 K250 T251 Q252	I244-V248 WeakPolarHBondContact O-CG2 3.28Å; I244-V248 PolarHBondContact O-N 2.9Å; E245-V248 PolarHBondContact O-N 3.5Å; V248-K250 VanDerWaalsContact C-N 3.26Å; V248-K250 PolarHBondContact O-N 3.44Å; V248-T251 PolarHBondContact O-N 3.05Å; V248-Q252 WeakPolarHBondContact O-CG 3.42Å; V248-Q252 PolarHBondContact O-N 3.5Å
249	L	92.6	Very high	92.1	Very high	42 Å²	42	69.3 Å²	69.3	22%	0.22	37%	0.371	C	S	.	.	H	α-helix	trans	-59.8	-36	177	-69.6	174.3	0	0	0	112.6	E245 R246 G253 N254 L255	E245-L249 WeakPolarHBondContact O-CG 3.33Å; E245-L249 PolarHBondContact O-N 3.45Å; R246-L249 PolarHBondContact O-N 3.43Å; L249-G253 PolarHBondContact O-N 3.49Å; L249-N254 HydrophobicContact CD2-CB 4.2Å; L249-N254 PolarHBondContact O-N 3.47Å; L249-L255 HydrophobicContact CB-CB 4.45Å; L249-L255 HydrophobicContact CB-CD1 4.32Å; L249-L255 PolarHBondContact O-N 2.85Å; L249-L255 VanDerWaalsContact O-N 3.14Å
250	K	91.6	Very high	92.2	Very high	151 Å²	151	71.6 Å²	71.6	66%	0.657	39%	0.386	S	S	*	.	H	α-helix	trans	-67.9	-44.6	176.7	-171.5	178.8	177.4	-177.2	0	111.9	R246 T247 V248 Q252 G253 L255	R246-K250 WeakPolarHBondContact O-CB 3.48Å; R246-K250 PolarHBondContact O-N 2.93Å; T247-K250 WeakPolarHBondContact O-CB 3.15Å; T247-K250 PolarHBondContact O-N 2.87Å; V248-K250 VanDerWaalsContact C-N 3.26Å; V248-K250 PolarHBondContact O-N 3.44Å; K250-Q252 VanDerWaalsContact C-N 3.26Å; K250-Q252 PolarHBondContact O-N 3.21Å; K250-G253 PolarHBondContact O-N 2.7Å; K250-L255 HydrophobicContact CB-CB 4.4Å; K250-L255 HydrophobicContact CB-CD2 4.24Å; K250-L255 HydrophobicContact CG-CD2 4.33Å
251	T	93.4	Very high	92.4	Very high	122 Å²	122	68.3 Å²	68.3	75%	0.748	37%	0.371	S	S	*	.	H	α-helix	trans	-63.4	-34.6	177	-57.3	0	0	0	0	111.7	T247 V248 G253	T247-T251 PolarHBondContact O-N 3.49Å; T247-T251 PolarHBondContact O-OG1 3.08Å; T247-T251 VanDerWaalsContact O-OG1 3.11Å; V248-T251 PolarHBondContact O-N 3.05Å; T251-G253 VanDerWaalsContact C-N 3.26Å; T251-G253 PolarHBondContact O-N 2.86Å
252	Q	93.9	Very high	92.6	Very high	116 Å²	116	71.8 Å²	71.8	54%	0.542	38%	0.384	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.9	-5.6	175.2	-66.9	175.2	-2.3	0	0	113.9	V248 K250 N254	V248-Q252 WeakPolarHBondContact O-CG 3.42Å; V248-Q252 PolarHBondContact O-N 3.5Å; K250-Q252 VanDerWaalsContact C-N 3.26Å; K250-Q252 PolarHBondContact O-N 3.21Å; Q252-N254 HydrophobicContact CB-CB 4.36Å; Q252-N254 PolarHBondContact O-N 3.49Å; Q252-N254 PolarHBondContact OE1-ND2 3.37Å
253	G	90.6	Very high	92.8	Very high	64 Å²	64	78.9 Å²	78.9	66%	0.66	41%	0.41	S	S	*	.	T	Hydrogen-bonded Turn	trans	70.1	9.3	-174.5	0	0	0	0	0	114.6	L249 K250 T251	L249-G253 PolarHBondContact O-N 3.49Å; K250-G253 PolarHBondContact O-N 2.7Å; T251-G253 VanDerWaalsContact C-N 3.26Å; T251-G253 PolarHBondContact O-N 2.86Å
254	N	91.7	Very high	93.1	Very high	106 Å²	106	75.4 Å²	75.4	57%	0.567	40%	0.397	S	S	*	.			trans	-91.7	-2.4	-177	-71	-26.6	0	0	0	113.3	L249 Q252 P256	L249-N254 HydrophobicContact CD2-CB 4.2Å; L249-N254 PolarHBondContact O-N 3.47Å; Q252-N254 HydrophobicContact CB-CB 4.36Å; Q252-N254 PolarHBondContact O-N 3.49Å; Q252-N254 PolarHBondContact OE1-ND2 3.37Å; N254-P256 WeakPolarHBondContact O-CD 3.34Å
255	L	90.5	Very high	93.2	Very high	41 Å²	41	73.9 Å²	73.9	22%	0.215	39%	0.389	C	S	.	.	P	Polyproline II helix	trans	-64.8	118.7	178.3	-171.6	73.2	0	0	0	110.2	R246 L249 K250 K257	R246-L255 HydrophobicContact CG-CD1 3.64Å; L249-L255 HydrophobicContact CB-CB 4.45Å; L249-L255 HydrophobicContact CB-CD1 4.32Å; L249-L255 PolarHBondContact O-N 2.85Å; L249-L255 VanDerWaalsContact O-N 3.14Å; K250-L255 HydrophobicContact CB-CB 4.4Å; K250-L255 HydrophobicContact CB-CD2 4.24Å; K250-L255 HydrophobicContact CG-CD2 4.33Å; L255-K257 PolarHBondContact O-N 2.9Å
256	P	89.3	Confident	93.5	Very high	42 Å²	42	78.9 Å²	78.9	27%	0.273	41%	0.414	S	S	.	.	P	Polyproline II helix	trans	-63.2	133.9	180	25.1	-33.1	0	0	0	110.6	N254 V393 V395	N254-P256 WeakPolarHBondContact O-CD 3.34Å; P256-V393 HydrophobicContact CB-CG1 3.7Å; P256-V395 HydrophobicContact CB-CG2 4.14Å; P256-V395 HydrophobicContact CG-CG2 4.11Å
257	K	90.6	Very high	93.7	Very high	188 Å²	188	77 Å²	77	82%	0.817	41%	0.408	S	S	*	.	P	Polyproline II helix	trans	-83.9	119	173.5	-66.3	-179.8	-178.7	175.4	0	108.6	L255	L255-K257 PolarHBondContact O-N 2.9Å
258	G	91.1	Very high	93.9	Very high	23 Å²	23	76.6 Å²	76.6	24%	0.237	41%	0.407	C	S	.	.	P	Polyproline II helix	trans	-57.7	146.4	177	0	0	0	0	0	112.3
259	T	94.8	Very high	94	Very high	18 Å²	18	77.3 Å²	77.3	11%	0.11	40%	0.404	C	S	.	.	P	Polyproline II helix	trans	-72.5	128.3	174.7	-59.4	0	0	0	0	108.2	I261 R263 L264 V393	T259-I261 PolarHBondContact O-N 3.45Å; T259-R263 HydrophobicContact CG2-CB 3.94Å; T259-L264 HydrophobicContact CG2-CD2 3.76Å; T259-L264 HydrophobicContact CG2-CG 4.01Å; T259-V393 PolarHBondContact OG1-N 3.12Å
260	P	95.4	Very high	94.3	Very high	50 Å²	50	75.3 Å²	75.3	33%	0.325	39%	0.394	S	S	.	.	P	Polyproline II helix	trans	-63.5	141.3	-175.1	27.9	-36.3	0	0	0	111	H262 R263 L264	P260-H262 VanDerWaalsContact C-N 3.26Å; P260-H262 PolarHBondContact O-N 2.56Å; P260-H262 VanDerWaalsContact O-N 3.08Å; P260-R263 HydrophobicContact CG-CB 4.33Å; P260-R263 HydrophobicContact CG-CG 3.98Å; P260-R263 WeakPolarHBondContact O-CB 3.48Å; P260-R263 PolarHBondContact O-N 3.3Å; P260-L264 PolarHBondContact O-N 2.88Å
261	I	96.5	Very high	94.6	Very high	17 Å²	17	70 Å²	70	9%	0.087	38%	0.379	C	S	.	.	H	α-helix	trans	-51.2	-38.9	-172.3	-165.3	174.7	0	0	0	114.4	P116 T259 R263 L264 L265 A401 I402 I405	P116-I261 HydrophobicContact CB-CD1 4.34Å; T259-I261 PolarHBondContact O-N 3.45Å; I261-R263 VanDerWaalsContact C-N 3.27Å; I261-R263 PolarHBondContact O-N 2.89Å; I261-L264 PolarHBondContact O-N 3.32Å; I261-L264 VanDerWaalsContact O-N 3.13Å; I261-L265 HydrophobicContact CG1-CD1 4.34Å; I261-L265 PolarHBondContact O-N 3.4Å; I261-A401 HydrophobicContact CD1-CB 4.19Å; I261-I402 HydrophobicContact CD1-CG1 4.08Å; I261-I402 HydrophobicContact CG1-CD1 4.01Å; I261-I402 HydrophobicContact CG1-CG1 3.82Å; I261-I405 HydrophobicContact CD1-CD1 4.22Å
262	H	95.5	Very high	94.8	Very high	101 Å²	101	65.1 Å²	65.1	47%	0.468	35%	0.348	S	S	.	.	H	α-helix	trans	-63.1	-31.4	179.7	67.1	-89.6	0	0	0	113	P260 M266	P260-H262 VanDerWaalsContact C-N 3.26Å; P260-H262 PolarHBondContact O-N 2.56Å; P260-H262 VanDerWaalsContact O-N 3.08Å; H262-M266 VanDerWaalsContact O-CG 3.27Å; H262-M266 WeakPolarHBondContact O-CG 3.45Å; H262-M266 PolarHBondContact O-N 3.29Å
263	R	96.9	Very high	95	Very high	161 Å²	161	59.6 Å²	59.6	61%	0.608	32%	0.322	S	S	*	.	H	α-helix	trans	-74.5	-35.8	175.1	-71.8	-171.9	-176.5	178.3	-1.8	111.8	T259 P260 I261 M266 D267	T259-R263 HydrophobicContact CG2-CB 3.94Å; P260-R263 HydrophobicContact CG-CB 4.33Å; P260-R263 HydrophobicContact CG-CG 3.98Å; P260-R263 WeakPolarHBondContact O-CB 3.48Å; P260-R263 PolarHBondContact O-N 3.3Å; I261-R263 VanDerWaalsContact C-N 3.27Å; I261-R263 PolarHBondContact O-N 2.89Å; R263-M266 PolarHBondContact O-N 3.1Å; R263-D267 PolarHBondContact O-N 3.46Å
264	L	97.2	Very high	95.4	Very high	1 Å²	1	57.1 Å²	57.1	1%	0.005	30%	0.295	C	S	.	.	H	α-helix	trans	-67.6	-39.9	175.1	-63.3	-179.5	0	0	0	111.2	T259 P260 I261 M266 D267 I270 V388 H392 V399 I402	T259-L264 HydrophobicContact CG2-CD2 3.76Å; T259-L264 HydrophobicContact CG2-CG 4.01Å; P260-L264 PolarHBondContact O-N 2.88Å; I261-L264 PolarHBondContact O-N 3.32Å; I261-L264 VanDerWaalsContact O-N 3.13Å; L264-M266 PolarHBondContact O-N 2.87Å; L264-D267 WeakPolarHBondContact O-CB 3.37Å; L264-D267 PolarHBondContact O-N 3.16Å; L264-I270 HydrophobicContact CB-CD1 4.11Å; L264-I270 HydrophobicContact CD2-CD1 3.8Å; L264-I270 HydrophobicContact CG-CD1 4.49Å; L264-V388 HydrophobicContact CD2-CG2 4.44Å; L264-H392 HydrophobicContact CD2-CB 3.95Å; L264-H392 VanDerWaalsContact CD2-CG 3.43Å; L264-V399 HydrophobicContact CD1-CB 4.34Å; L264-I402 HydrophobicContact CB-CD1 3.61Å
265	L	95.5	Very high	95.7	Very high	80 Å²	80	53 Å²	53	42%	0.419	28%	0.277	S	S	.	.	H	α-helix	trans	-63	-28.2	173.2	-77.6	169.9	0	0	0	113.2	I261 D267 I402	I261-L265 HydrophobicContact CG1-CD1 4.34Å; I261-L265 PolarHBondContact O-N 3.4Å; L265-D267 VanDerWaalsContact C-N 3.33Å; L265-I402 HydrophobicContact CD2-CB 4.46Å; L265-I402 HydrophobicContact CD2-CD1 3.92Å; L265-I402 HydrophobicContact CD2-CG1 3.78Å; L265-I402 HydrophobicContact CD2-CG2 3.87Å; L265-I402 HydrophobicContact CG-CD1 3.8Å; L265-I402 HydrophobicContact CG-CG1 3.96Å
266	M	96.7	Very high	96	Very high	152 Å²	152	51 Å²	51	75%	0.749	27%	0.267	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81	-10.3	174.2	-71.2	178.4	179.2	0	0	113.2	H262 R263 L264	H262-M266 VanDerWaalsContact O-CG 3.27Å; H262-M266 WeakPolarHBondContact O-CG 3.45Å; H262-M266 PolarHBondContact O-N 3.29Å; R263-M266 PolarHBondContact O-N 3.1Å; L264-M266 PolarHBondContact O-N 2.87Å
267	D	97	Very high	96.5	Very high	8 Å²	8	49 Å²	49	4%	0.043	25%	0.254	C	S	.	.	S	Bend	trans	-73.2	121.9	174.6	-171.6	-57.1	0	0	0	109.7	R263 L264 L265 Y269 I270 A271 R391 H392	R263-D267 PolarHBondContact O-N 3.46Å; L264-D267 WeakPolarHBondContact O-CB 3.37Å; L264-D267 PolarHBondContact O-N 3.16Å; L265-D267 VanDerWaalsContact C-N 3.33Å; D267-Y269 VanDerWaalsContact C-N 3.29Å; D267-Y269 PolarHBondContact O-N 3.15Å; D267-Y269 PolarHBondContact OD1-N 3.43Å; D267-I270 HydrophobicContact CB-CB 4.09Å; D267-I270 HydrophobicContact CB-CD1 4Å; D267-I270 HydrophobicContact CB-CG1 4.03Å; D267-I270 PolarHBondContact O-N 3.23Å; D267-I270 PolarHBondContact OD1-N 3.45Å; D267-A271 WeakPolarHBondContact O-CB 3.4Å; D267-A271 PolarHBondContact O-N 3.06Å; D267-R391 IonicContact OD1-CZ 3.47Å; D267-R391 IonicContact OD1-NH1 3.18Å; D267-R391 PolarHBondContact OD1-NH1 3.27Å; D267-R391 IonicContact OD1-NH2 3.82Å; D267-R391 IonicContact OD2-CZ 3.13Å; D267-R391 IonicContact OD2-NE 3.17Å; D267-R391 PolarHBondContact OD2-NE 3.48Å; D267-R391 IonicContact OD2-NH1 3.66Å; D267-R391 IonicContact OD2-NH2 3.34Å; D267-R391 PolarHBondContact OD2-NH2 3Å; D267-H392 IonicContact OD2-CD2 3.85Å; D267-H392 IonicContact OD2-CE1 3.68Å; D267-H392 IonicContact OD2-NE2 2.82Å; D267-H392 PolarHBondContact OD2-NE2 3.4Å
268	P	96.6	Very high	96.8	Very high	75 Å²	75	41.3 Å²	41.3	49%	0.487	22%	0.223	S	C	.	.	H	α-helix	trans	-61.8	-32.9	-174.9	23.9	-34.2	0	0	0	113.3	I272	P268-I272 WeakPolarHBondContact O-CB 3.17Å; P268-I272 VanDerWaalsContact O-CD1 3.28Å; P268-I272 WeakPolarHBondContact O-CD1 3.09Å; P268-I272 WeakPolarHBondContact O-CG1 3.42Å; P268-I272 PolarHBondContact O-N 2.96Å
269	Y	97.1	Very high	97.1	Very high	65 Å²	65	41.1 Å²	41.1	26%	0.255	22%	0.217	S	C	.	.	H	α-helix	trans	-76.3	-39.9	179.5	-65.5	-24.4	0	0	0	111.6	D267 A271 I272 C273 L387 L447 L448 C451	D267-Y269 VanDerWaalsContact C-N 3.29Å; D267-Y269 PolarHBondContact O-N 3.15Å; D267-Y269 PolarHBondContact OD1-N 3.43Å; Y269-A271 VanDerWaalsContact C-N 3.33Å; Y269-I272 HydrophobicContact CD1-CD1 4.46Å; Y269-I272 PolarHBondContact O-N 3.19Å; Y269-C273 PolarHBondContact O-N 3.37Å; Y269-C273 PolarHBondContact O-SG 3.41Å; Y269-C273 VanDerWaalsContact O-SG 3.39Å; Y269-L387 HydrophobicContact CD2-CD2 3.73Å; Y269-L387 HydrophobicContact CG-CD2 4.16Å; Y269-L447 WeakPolarHBondContact CE1-O 3.43Å; Y269-L448 HydrophobicContact CD1-CD2 3.68Å; Y269-L448 HydrophobicContact CG-CD2 3.79Å; Y269-C451 HydrophobicContact CD2-CB 4.13Å; Y269-C451 HydrophobicContact CE2-CB 4.34Å
270	I	97.8	Very high	97.3	Very high	0 Å²	0	40.2 Å²	40.2	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-65	-41.3	175	-61.1	179.1	0	0	0	109.9	L264 D267 I272 C273 A274 M384 L387 V388 V399 I402	L264-I270 HydrophobicContact CB-CD1 4.11Å; L264-I270 HydrophobicContact CD2-CD1 3.8Å; L264-I270 HydrophobicContact CG-CD1 4.49Å; D267-I270 HydrophobicContact CB-CB 4.09Å; D267-I270 HydrophobicContact CB-CD1 4Å; D267-I270 HydrophobicContact CB-CG1 4.03Å; D267-I270 PolarHBondContact O-N 3.23Å; D267-I270 PolarHBondContact OD1-N 3.45Å; I270-I272 PolarHBondContact O-N 3.17Å; I270-C273 WeakPolarHBondContact O-CB 3.44Å; I270-C273 PolarHBondContact O-N 3.28Å; I270-A274 WeakPolarHBondContact O-CB 3.26Å; I270-A274 PolarHBondContact O-N 2.88Å; I270-M384 HydrophobicContact CG2-CE 3.86Å; I270-L387 HydrophobicContact CG1-CB 4.11Å; I270-L387 HydrophobicContact CG1-CD1 4.08Å; I270-V388 HydrophobicContact CD1-CG2 4.22Å; I270-V399 HydrophobicContact CG2-CG2 4.44Å; I270-I402 HydrophobicContact CG2-CD1 4.06Å; I270-I402 HydrophobicContact CG2-CG2 4.35Å
271	A	97.9	Very high	97.3	Very high	41 Å²	41	38.2 Å²	38.2	34%	0.339	20%	0.198	S	C	.	.	H	α-helix	trans	-62	-40.8	175.2	0	0	0	0	0	112.4	D267 Y269 A274 G275	D267-A271 WeakPolarHBondContact O-CB 3.4Å; D267-A271 PolarHBondContact O-N 3.06Å; Y269-A271 VanDerWaalsContact C-N 3.33Å; A271-A274 PolarHBondContact O-N 3Å; A271-G275 PolarHBondContact O-N 3.37Å
272	I	98.2	Very high	97.2	Very high	19 Å²	19	38.4 Å²	38.4	10%	0.097	20%	0.2	C	C	.	.	H	α-helix	trans	-63.9	-42.8	175	-69.4	160.7	0	0	0	111.1	P268 Y269 I270 G275 C276 Y441 V444 M445 L447 L448	P268-I272 WeakPolarHBondContact O-CB 3.17Å; P268-I272 VanDerWaalsContact O-CD1 3.28Å; P268-I272 WeakPolarHBondContact O-CD1 3.09Å; P268-I272 WeakPolarHBondContact O-CG1 3.42Å; P268-I272 PolarHBondContact O-N 2.96Å; Y269-I272 HydrophobicContact CD1-CD1 4.46Å; Y269-I272 PolarHBondContact O-N 3.19Å; I270-I272 PolarHBondContact O-N 3.17Å; I272-G275 PolarHBondContact O-N 3.12Å; I272-C276 VanDerWaalsContact O-CB 3.32Å; I272-C276 WeakPolarHBondContact O-CB 3.46Å; I272-C276 PolarHBondContact O-N 2.98Å; I272-Y441 WeakPolarHBondContact CA-OH 3.43Å; I272-Y441 HydrophobicContact CG2-CE1 4.46Å; I272-Y441 PolarHBondContact O-OH 2.65Å; I272-V444 HydrophobicContact CG1-CG1 4.12Å; I272-V444 HydrophobicContact CG2-CG1 4.05Å; I272-M445 HydrophobicContact CG2-SD 4.24Å; I272-L447 HydrophobicContact CD1-CB 3.84Å; I272-L447 HydrophobicContact CD1-CD1 3.96Å; I272-L448 HydrophobicContact CB-CD2 4.4Å; I272-L448 HydrophobicContact CB-CG 4.44Å; I272-L448 HydrophobicContact CG2-CD1 3.77Å; I272-L448 HydrophobicContact CG2-CD2 4.37Å; I272-L448 HydrophobicContact CG2-CG 3.88Å
273	C	98.4	Very high	97.1	Very high	0 Å²	0	33.8 Å²	33.8	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-60.4	-47.6	174.1	-72.9	0	0	0	0	111.5	Y269 I270 G275 C276 L277 I380 M384	Y269-C273 PolarHBondContact O-N 3.37Å; Y269-C273 PolarHBondContact O-SG 3.41Å; Y269-C273 VanDerWaalsContact O-SG 3.39Å; I270-C273 WeakPolarHBondContact O-CB 3.44Å; I270-C273 PolarHBondContact O-N 3.28Å; C273-G275 PolarHBondContact O-N 3.36Å; C273-C276 WeakPolarHBondContact O-CB 3.43Å; C273-C276 PolarHBondContact O-N 2.89Å; C273-C276 VanDerWaalsContact O-N 3.15Å; C273-L277 WeakPolarHBondContact O-CG 3.26Å; C273-L277 PolarHBondContact O-N 3.4Å; C273-I380 HydrophobicContact CB-CG2 3.6Å; C273-M384 HydrophobicContact CB-CG 3.54Å; C273-M384 HydrophobicContact CB-SD 4.04Å
274	A	98.3	Very high	97	Very high	11 Å²	11	27 Å²	27	9%	0.091	16%	0.155	C	C	.	.	H	α-helix	trans	-61.8	-41.8	178.5	0	0	0	0	0	112.3	I270 A271 T278 I402 S406	I270-A274 WeakPolarHBondContact O-CB 3.26Å; I270-A274 PolarHBondContact O-N 2.88Å; A271-A274 PolarHBondContact O-N 3Å; A274-T278 PolarHBondContact O-N 3.22Å; A274-T278 VanDerWaalsContact O-N 3.09Å; A274-T278 PolarHBondContact O-OG1 3.07Å; A274-I402 HydrophobicContact CB-CG2 3.57Å; A274-S406 VanDerWaalsContact C-OG 3.29Å; A274-S406 VanDerWaalsContact CA-OG 3.26Å; A274-S406 WeakPolarHBondContact CA-OG 3.45Å; A274-S406 WeakPolarHBondContact CB-OG 3.41Å; A274-S406 VanDerWaalsContact O-CB 3.29Å; A274-S406 WeakPolarHBondContact O-CB 3.32Å; A274-S406 PolarHBondContact O-OG 3.44Å
275	G	97.9	Very high	96.8	Very high	19 Å²	19	27 Å²	27	20%	0.196	15%	0.154	C	C	.	.	H	α-helix	trans	-65	-38.6	173.7	0	0	0	0	0	112.3	A271 I272 C273 T278 V279 Y441	A271-G275 PolarHBondContact O-N 3.37Å; I272-G275 PolarHBondContact O-N 3.12Å; C273-G275 PolarHBondContact O-N 3.36Å; G275-T278 WeakPolarHBondContact O-CB 3.05Å; G275-T278 PolarHBondContact O-N 3.33Å; G275-V279 WeakPolarHBondContact O-CB 3.34Å; G275-V279 WeakPolarHBondContact O-CG2 3.31Å; G275-V279 PolarHBondContact O-N 2.55Å; G275-Y441 WeakPolarHBondContact CA-OH 3.29Å
276	C	98.4	Very high	96.6	Very high	0 Å²	0	23.8 Å²	23.8	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-61.1	-48.4	176	-172.6	0	0	0	0	111.7	I272 C273 T278 V279 A280 V376 Y441 M445	I272-C276 VanDerWaalsContact O-CB 3.32Å; I272-C276 WeakPolarHBondContact O-CB 3.46Å; I272-C276 PolarHBondContact O-N 2.98Å; C273-C276 WeakPolarHBondContact O-CB 3.43Å; C273-C276 PolarHBondContact O-N 2.89Å; C273-C276 VanDerWaalsContact O-N 3.15Å; C276-T278 VanDerWaalsContact C-N 3.3Å; C276-T278 PolarHBondContact O-N 3.08Å; C276-V279 PolarHBondContact O-N 3.03Å; C276-A280 WeakPolarHBondContact O-CB 3.5Å; C276-A280 PolarHBondContact O-N 3.4Å; C276-V376 WeakPolarHBondContact SG-CG1 3.44Å; C276-Y441 HydrophobicContact CB-CD1 4.38Å; C276-Y441 HydrophobicContact CB-CE1 3.74Å; C276-Y441 PolarHBondContact N-OH 2.72Å; C276-M445 HydrophobicContact CB-CE 4.32Å; C276-M445 HydrophobicContact CB-SD 3.78Å
277	L	98.2	Very high	96.3	Very high	0 Å²	0	16.8 Å²	16.8	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-59.3	-41.9	175.8	-67.9	178	0	0	0	111.8	C273 N281 D377 I380 L381 M384 A403 Y407	C273-L277 WeakPolarHBondContact O-CG 3.26Å; C273-L277 PolarHBondContact O-N 3.4Å; L277-N281 WeakPolarHBondContact O-CB 3.3Å; L277-N281 PolarHBondContact O-N 3.08Å; L277-N281 VanDerWaalsContact O-N 3.12Å; L277-N281 PolarHBondContact O-ND2 2.94Å; L277-D377 VanDerWaalsContact CD2-OD1 3.24Å; L277-D377 WeakPolarHBondContact CD2-OD1 3.47Å; L277-I380 HydrophobicContact CD1-CG2 4.15Å; L277-I380 HydrophobicContact CD2-CB 3.93Å; L277-I380 HydrophobicContact CD2-CG2 3.86Å; L277-I380 HydrophobicContact CG-CB 4.39Å; L277-I380 HydrophobicContact CG-CG2 3.77Å; L277-L381 HydrophobicContact CD1-CD2 4.14Å; L277-M384 HydrophobicContact CD1-SD 3.85Å; L277-A403 HydrophobicContact CD1-CB 3.73Å; L277-Y407 HydrophobicContact CD2-CE1 4.29Å; L277-Y407 WeakPolarHBondContact CD2-OH 3.32Å
278	T	97.8	Very high	95.8	Very high	27 Å²	27	18.2 Å²	18.2	17%	0.166	11%	0.109	C	C	.	.	H	α-helix	trans	-62.8	-50.1	177.3	-52.6	0	0	0	0	110.4	A274 G275 C276 A280 N281 V282 S406 L409	A274-T278 PolarHBondContact O-N 3.22Å; A274-T278 VanDerWaalsContact O-N 3.09Å; A274-T278 PolarHBondContact O-OG1 3.07Å; G275-T278 WeakPolarHBondContact O-CB 3.05Å; G275-T278 PolarHBondContact O-N 3.33Å; C276-T278 VanDerWaalsContact C-N 3.3Å; C276-T278 PolarHBondContact O-N 3.08Å; T278-A280 VanDerWaalsContact C-N 3.34Å; T278-A280 PolarHBondContact O-N 2.98Å; T278-N281 PolarHBondContact O-N 2.98Å; T278-V282 VanDerWaalsContact O-CB 3.32Å; T278-V282 WeakPolarHBondContact O-CB 3.08Å; T278-V282 PolarHBondContact O-N 3.46Å; T278-S406 WeakPolarHBondContact OG1-CA 3.48Å; T278-S406 WeakPolarHBondContact OG1-CB 3.48Å; T278-S406 PolarHBondContact OG1-OG 2.79Å; T278-L409 HydrophobicContact CG2-CD2 3.95Å; T278-L409 HydrophobicContact CG2-CG 4.3Å
279	V	97.4	Very high	95	Very high	18 Å²	18	17.4 Å²	17.4	11%	0.109	10%	0.104	C	C	.	.	H	α-helix	trans	-64.1	-37.6	-178.8	168.6	0	0	0	0	111.9	G275 C276 V282 L343 I437 T438 Y441	G275-V279 WeakPolarHBondContact O-CB 3.34Å; G275-V279 WeakPolarHBondContact O-CG2 3.31Å; G275-V279 PolarHBondContact O-N 2.55Å; C276-V279 PolarHBondContact O-N 3.03Å; V279-V282 VanDerWaalsContact O-CG1 3.3Å; V279-V282 WeakPolarHBondContact O-CG1 3.33Å; V279-L343 HydrophobicContact CG1-CD2 4.01Å; V279-I437 HydrophobicContact CG1-CG2 4.08Å; V279-I437 HydrophobicContact CG2-CG2 4.16Å; V279-T438 HydrophobicContact CG1-CG2 3.97Å; V279-Y441 HydrophobicContact CB-CG 4.44Å; V279-Y441 HydrophobicContact CG1-CG 4.41Å; V279-Y441 HydrophobicContact CG2-CD2 3.86Å; V279-Y441 HydrophobicContact CG2-CE2 4.32Å; V279-Y441 HydrophobicContact CG2-CG 4.1Å
280	A	97.8	Very high	94.6	Very high	0 Å²	0	14.8 Å²	14.8	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-69.8	-36.1	178.2	0	0	0	0	0	112.7	C276 T278 L343 E346 I373 V376	C276-A280 WeakPolarHBondContact O-CB 3.5Å; C276-A280 PolarHBondContact O-N 3.4Å; T278-A280 VanDerWaalsContact C-N 3.34Å; T278-A280 PolarHBondContact O-N 2.98Å; A280-L343 HydrophobicContact CB-CD2 3.97Å; A280-E346 WeakPolarHBondContact CA-OE2 3.2Å; A280-E346 WeakPolarHBondContact CB-OE2 3.38Å; A280-I373 WeakPolarHBondContact O-CD1 3.45Å; A280-I373 WeakPolarHBondContact O-CG1 3.25Å; A280-V376 HydrophobicContact CB-CB 3.96Å; A280-V376 HydrophobicContact CB-CG1 3.73Å; A280-V376 HydrophobicContact CB-CG2 4.09Å
281	N	96.1	Very high	94.2	Very high	8 Å²	8	14.8 Å²	14.8	4%	0.043	10%	0.095	C	C	.	.	H	α-helix	trans	-87.5	-20	-177.4	-74.6	-93.9	0	0	0	112.9	L277 T278 S283 L284 A285 D377 Y407 A410	L277-N281 WeakPolarHBondContact O-CB 3.3Å; L277-N281 PolarHBondContact O-N 3.08Å; L277-N281 VanDerWaalsContact O-N 3.12Å; L277-N281 PolarHBondContact O-ND2 2.94Å; T278-N281 PolarHBondContact O-N 2.98Å; N281-S283 VanDerWaalsContact C-N 3.3Å; N281-S283 PolarHBondContact O-N 3.38Å; N281-L284 PolarHBondContact O-N 3.24Å; N281-A285 WeakPolarHBondContact O-CB 3.48Å; N281-A285 PolarHBondContact O-N 3.05Å; N281-D377 PolarHBondContact ND2-OD1 2.79Å; N281-Y407 HydrophobicContact CB-CD1 4.28Å; N281-Y407 WeakPolarHBondContact ND2-CD1 3.39Å; N281-Y407 WeakPolarHBondContact ND2-CE1 3.29Å; N281-A410 HydrophobicContact CB-CB 3.86Å
282	V	94.6	Very high	93.6	Very high	20 Å²	20	14.4 Å²	14.4	12%	0.121	9%	0.09	C	C	.	.	H	α-helix	trans	-62.5	-38.9	179	85.4	0	0	0	0	111.3	T278 V279 L284 A285 F286 A410 M434	T278-V282 VanDerWaalsContact O-CB 3.32Å; T278-V282 WeakPolarHBondContact O-CB 3.08Å; T278-V282 PolarHBondContact O-N 3.46Å; V279-V282 VanDerWaalsContact O-CG1 3.3Å; V279-V282 WeakPolarHBondContact O-CG1 3.33Å; V282-L284 VanDerWaalsContact C-N 3.34Å; V282-L284 PolarHBondContact O-N 2.99Å; V282-A285 PolarHBondContact O-N 3.26Å; V282-F286 HydrophobicContact CG2-CD2 3.53Å; V282-F286 HydrophobicContact CG2-CE2 3.35Å; V282-F286 VanDerWaalsContact O-CD2 3.23Å; V282-F286 WeakPolarHBondContact O-CD2 3.18Å; V282-F286 PolarHBondContact O-N 3.01Å; V282-A410 HydrophobicContact CB-CB 4.35Å; V282-M434 HydrophobicContact CG1-SD 4.02Å
283	S	94.1	Very high	92.9	Very high	4 Å²	4	15.8 Å²	15.8	3%	0.028	10%	0.097	C	C	.	.	H	α-helix	trans	-59.8	-45.4	-179.9	-54.8	0	0	0	0	111.7	N281 L287 E346 T438	N281-S283 VanDerWaalsContact C-N 3.3Å; N281-S283 PolarHBondContact O-N 3.38Å; S283-L287 VanDerWaalsContact O-CB 3.25Å; S283-L287 WeakPolarHBondContact O-CB 3.34Å; S283-L287 PolarHBondContact O-N 3.46Å; S283-L287 VanDerWaalsContact O-N 3.1Å; S283-E346 WeakPolarHBondContact CB-OE1 3.48Å; S283-E346 PolarHBondContact OG-OE1 3.43Å; S283-T438 WeakPolarHBondContact OG-CG2 3.37Å
284	L	94	Very high	92.4	Very high	19 Å²	19	17.2 Å²	17.2	10%	0.099	10%	0.103	C	C	.	.	H	α-helix	trans	-68.4	-45.4	176.7	-175.2	60	0	0	0	111.6	N281 V282 F286 L287 E288 W310 L369 I373	N281-L284 PolarHBondContact O-N 3.24Å; V282-L284 VanDerWaalsContact C-N 3.34Å; V282-L284 PolarHBondContact O-N 2.99Å; L284-F286 PolarHBondContact O-N 3.21Å; L284-L287 PolarHBondContact O-N 3.47Å; L284-E288 HydrophobicContact CD1-CG 4.29Å; L284-E288 HydrophobicContact CG-CG 4.44Å; L284-E288 PolarHBondContact O-N 2.7Å; L284-W310 HydrophobicContact CD1-CE3 4.47Å; L284-W310 HydrophobicContact CD1-CH2 3.76Å; L284-W310 HydrophobicContact CD1-CZ3 3.46Å; L284-W310 VanDerWaalsContact CD1-CZ3 3.46Å; L284-L369 HydrophobicContact CB-CD2 4.25Å; L284-L369 HydrophobicContact CD1-CD2 4.06Å; L284-I373 HydrophobicContact CB-CD1 3.73Å; L284-I373 HydrophobicContact CD2-CD1 4.06Å; L284-I373 HydrophobicContact CG-CD1 4.46Å
285	A	92.2	Very high	91.9	Very high	0 Å²	0	16.7 Å²	16.7	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-62.2	-28.4	-179.3	0	0	0	0	0	114	N281 V282 P289 A410 Y411	N281-A285 WeakPolarHBondContact O-CB 3.48Å; N281-A285 PolarHBondContact O-N 3.05Å; V282-A285 PolarHBondContact O-N 3.26Å; A285-P289 WeakPolarHBondContact O-CD 3.49Å; A285-A410 HydrophobicContact CB-CB 4.37Å; A285-A410 VanDerWaalsContact CB-O 3.29Å; A285-A410 WeakPolarHBondContact CB-O 3.43Å; A285-Y411 HydrophobicContact CB-CD1 3.93Å; A285-Y411 HydrophobicContact CB-CE1 4.21Å; A285-Y411 HydrophobicContact CB-CG 4.25Å
286	F	91.1	Very high	91.3	Very high	13 Å²	13	18.6 Å²	18.6	6%	0.057	11%	0.109	C	C	.	.	H	α-helix	trans	-83.4	-32.6	172.3	-86.6	-101.8	0	0	0	112.7	V282 L284 P289 T290 V417 A418 L421 L430 M434	V282-F286 HydrophobicContact CG2-CD2 3.53Å; V282-F286 HydrophobicContact CG2-CE2 3.35Å; V282-F286 VanDerWaalsContact O-CD2 3.23Å; V282-F286 WeakPolarHBondContact O-CD2 3.18Å; V282-F286 PolarHBondContact O-N 3.01Å; L284-F286 PolarHBondContact O-N 3.21Å; F286-P289 WeakPolarHBondContact O-CD 3.43Å; F286-T290 WeakPolarHBondContact O-CG2 3.48Å; F286-T290 PolarHBondContact O-OG1 3Å; F286-V417 HydrophobicContact CE1-CB 3.8Å; F286-V417 HydrophobicContact CE1-CG1 3.82Å; F286-V417 HydrophobicContact CZ-CB 3.73Å; F286-V417 HydrophobicContact CZ-CG1 3.91Å; F286-A418 HydrophobicContact CB-CB 4.38Å; F286-A418 HydrophobicContact CD1-CB 3.42Å; F286-A418 VanDerWaalsContact CD1-CB 3.42Å; F286-A418 HydrophobicContact CE1-CB 3.99Å; F286-A418 HydrophobicContact CG-CB 4.13Å; F286-L421 HydrophobicContact CE1-CD2 4.4Å; F286-L430 HydrophobicContact CD1-CD1 3.64Å; F286-L430 HydrophobicContact CE1-CD1 4.24Å; F286-L430 HydrophobicContact CG-CD1 4.46Å; F286-M434 HydrophobicContact CB-SD 4.46Å; F286-M434 HydrophobicContact CD1-CE 4.08Å; F286-M434 HydrophobicContact CD2-CE 4.31Å; F286-M434 HydrophobicContact CD2-SD 4.29Å; F286-M434 HydrophobicContact CE1-CE 4.15Å; F286-M434 HydrophobicContact CE2-CE 4.38Å; F286-M434 HydrophobicContact CG-CE 4.13Å; F286-M434 HydrophobicContact CG-SD 4.27Å; F286-M434 HydrophobicContact CZ-CE 4.29Å
287	L	91.4	Very high	90.8	Very high	5 Å²	5	25.3 Å²	25.3	3%	0.026	14%	0.138	C	C	.	.	H	α-helix	trans	-71.3	-43.6	-179	-173.6	65.1	0	0	0	111.8	S283 L284 T290 I291 W310 I353 I366 L369 F427	S283-L287 VanDerWaalsContact O-CB 3.25Å; S283-L287 WeakPolarHBondContact O-CB 3.34Å; S283-L287 PolarHBondContact O-N 3.46Å; S283-L287 VanDerWaalsContact O-N 3.1Å; L284-L287 PolarHBondContact O-N 3.47Å; L287-T290 PolarHBondContact O-N 2.99Å; L287-T290 VanDerWaalsContact O-N 3.12Å; L287-T290 PolarHBondContact O-OG1 2.96Å; L287-I291 HydrophobicContact CD1-CB 4.09Å; L287-I291 HydrophobicContact CD1-CD1 3.96Å; L287-I291 HydrophobicContact CD1-CG1 4.19Å; L287-I291 HydrophobicContact CD2-CD1 4.34Å; L287-I291 HydrophobicContact CG-CB 4.29Å; L287-I291 HydrophobicContact CG-CD1 4.08Å; L287-I291 VanDerWaalsContact O-CB 3.31Å; L287-I291 WeakPolarHBondContact O-CB 3.22Å; L287-I291 PolarHBondContact O-N 3.16Å; L287-W310 HydrophobicContact CB-CH2 4.38Å; L287-W310 HydrophobicContact CD2-CH2 3.76Å; L287-W310 HydrophobicContact CD2-CZ3 4.25Å; L287-W310 HydrophobicContact CG-CH2 3.88Å; L287-I353 HydrophobicContact CD1-CD1 4.12Å; L287-I353 HydrophobicContact CD1-CG2 4.07Å; L287-I353 HydrophobicContact CD2-CD1 3.64Å; L287-I366 HydrophobicContact CD2-CG1 4.4Å; L287-L369 HydrophobicContact CD2-CD1 4.12Å; L287-F427 HydrophobicContact CD1-CE2 4.22Å; L287-F427 HydrophobicContact CD1-CZ 3.91Å
288	E	86.8	Confident	90.3	Very high	38 Å²	38	28.7 Å²	28.7	18%	0.178	16%	0.162	C	C	.	.	H	α-helix	trans	-47.6	-56.1	-180	-79	-175.5	179.8	0	0	114.4	Y40 M41 L284 T290 W310	Y40-E288 PolarHBondContact OH-OE2 2.84Å; M41-E288 WeakPolarHBondContact CE-OE1 3.36Å; L284-E288 HydrophobicContact CD1-CG 4.29Å; L284-E288 HydrophobicContact CG-CG 4.44Å; L284-E288 PolarHBondContact O-N 2.7Å; E288-T290 VanDerWaalsContact C-N 3.3Å; E288-T290 PolarHBondContact O-N 3.23Å; E288-W310 HydrophobicContact CG-CH2 4.13Å; E288-W310 HydrophobicContact CG-CZ2 4.12Å
289	P	80.1	Confident	89.9	Confident	59 Å²	59	29.1 Å²	29.1	38%	0.383	16%	0.162	S	C	.	.	H	α-helix	trans	-75.3	-16.1	-177.9	28.8	-36.2	0	0	0	114	A285 F286 P415 A418	A285-P289 WeakPolarHBondContact O-CD 3.49Å; F286-P289 WeakPolarHBondContact O-CD 3.43Å; P289-P415 HydrophobicContact CG-CB 4.44Å; P289-A418 HydrophobicContact CG-CB 4.11Å
290	T	87.9	Confident	89.4	Confident	9 Å²	9	37.3 Å²	37.3	6%	0.055	20%	0.196	C	C	.	.	H	α-helix	trans	-104.5	-27.1	-171.4	59.3	0	0	0	0	113.6	F286 L287 E288 S292 W294 A418 V422 L430	F286-T290 WeakPolarHBondContact O-CG2 3.48Å; F286-T290 PolarHBondContact O-OG1 3Å; L287-T290 PolarHBondContact O-N 2.99Å; L287-T290 VanDerWaalsContact O-N 3.12Å; L287-T290 PolarHBondContact O-OG1 2.96Å; E288-T290 VanDerWaalsContact C-N 3.3Å; E288-T290 PolarHBondContact O-N 3.23Å; T290-S292 PolarHBondContact O-N 3.43Å; T290-W294 PolarHBondContact O-N 3.46Å; T290-A418 HydrophobicContact CG2-CB 3.64Å; T290-V422 HydrophobicContact CG2-CG2 3.57Å; T290-L430 HydrophobicContact CG2-CD2 4.02Å
291	I	88.9	Confident	88.6	Confident	0 Å²	0	37.8 Å²	37.8	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-66.3	-41.1	-171.7	-159.1	171	0	0	0	112.8	L287 N293 W294 M295 W310 L362 I366	L287-I291 HydrophobicContact CD1-CB 4.09Å; L287-I291 HydrophobicContact CD1-CD1 3.96Å; L287-I291 HydrophobicContact CD1-CG1 4.19Å; L287-I291 HydrophobicContact CD2-CD1 4.34Å; L287-I291 HydrophobicContact CG-CB 4.29Å; L287-I291 HydrophobicContact CG-CD1 4.08Å; L287-I291 VanDerWaalsContact O-CB 3.31Å; L287-I291 WeakPolarHBondContact O-CB 3.22Å; L287-I291 PolarHBondContact O-N 3.16Å; I291-N293 PolarHBondContact O-N 3.45Å; I291-W294 CarbonylContact O-C 3.46Å; I291-W294 PolarHBondContact O-N 3.17Å; I291-W294 VanDerWaalsContact O-N 3.16Å; I291-M295 HydrophobicContact CD1-SD 4.42Å; I291-M295 HydrophobicContact CG1-CG 4.16Å; I291-M295 HydrophobicContact CG1-SD 4Å; I291-M295 WeakPolarHBondContact O-CB 3.43Å; I291-M295 VanDerWaalsContact O-CG 3.3Å; I291-M295 WeakPolarHBondContact O-CG 3.46Å; I291-M295 PolarHBondContact O-N 3.18Å; I291-W310 HydrophobicContact CB-CZ2 4.5Å; I291-W310 HydrophobicContact CD1-CZ2 4.37Å; I291-W310 HydrophobicContact CG2-CZ2 3.54Å; I291-L362 HydrophobicContact CD1-CD1 4.39Å; I291-L362 HydrophobicContact CD1-CD2 4Å; I291-L362 HydrophobicContact CD1-CG 4.38Å; I291-L362 HydrophobicContact CG1-CD2 4.28Å; I291-I366 HydrophobicContact CD1-CD1 3.44Å; I291-I366 VanDerWaalsContact CD1-CD1 3.44Å; I291-I366 HydrophobicContact CD1-CG1 4.27Å
292	S	85.5	Confident	88	Confident	33 Å²	33	40.9 Å²	40.9	23%	0.231	22%	0.219	C	C	.	.	H	α-helix	trans	-60.5	-49.5	-178.8	-65.2	0	0	0	0	111.4	T290 W294 M295 S296 E306	T290-S292 PolarHBondContact O-N 3.43Å; S292-W294 VanDerWaalsContact C-N 3.28Å; S292-W294 PolarHBondContact O-N 3.01Å; S292-M295 PolarHBondContact O-N 3.05Å; S292-S296 WeakPolarHBondContact O-CB 3.45Å; S292-S296 PolarHBondContact O-N 3.15Å; S292-E306 WeakPolarHBondContact CB-OE2 3.05Å
293	N	83.3	Confident	87.1	Confident	49 Å²	49	46 Å²	46	26%	0.262	25%	0.246	S	C	.	.	H	α-helix	trans	-59.7	-39.2	176.3	-176.6	30.6	0	0	0	111.9	I291 K297	I291-N293 PolarHBondContact O-N 3.45Å; N293-K297 PolarHBondContact ND2-NZ 2.94Å; N293-K297 WeakPolarHBondContact O-CB 3.43Å; N293-K297 WeakPolarHBondContact O-CG 3.43Å; N293-K297 PolarHBondContact O-N 3.28Å; N293-K297 VanDerWaalsContact O-N 3.15Å; N293-K297 WeakPolarHBondContact OD1-CE 3.44Å; N293-K297 PolarHBondContact OD1-NZ 3.25Å
294	W	89	Confident	86.2	Confident	29 Å²	29	48.7 Å²	48.7	11%	0.11	27%	0.269	C	S	.	.	H	α-helix	trans	-69.6	-42.6	176.8	177.8	77.2	0	0	0	112.6	T290 I291 S292 K297 S298 M299 I353 C356 L362 F427	T290-W294 PolarHBondContact O-N 3.46Å; I291-W294 CarbonylContact O-C 3.46Å; I291-W294 PolarHBondContact O-N 3.17Å; I291-W294 VanDerWaalsContact O-N 3.16Å; S292-W294 VanDerWaalsContact C-N 3.28Å; S292-W294 PolarHBondContact O-N 3.01Å; W294-K297 PolarHBondContact O-N 2.83Å; W294-S298 PolarHBondContact NE1-OG 3.4Å; W294-S298 WeakPolarHBondContact O-CB 3.46Å; W294-S298 PolarHBondContact O-N 2.97Å; W294-S298 PolarHBondContact O-OG 3.49Å; W294-S298 VanDerWaalsContact O-OG 3.07Å; W294-M299 HydrophobicContact CH2-CE 3.56Å; W294-M299 HydrophobicContact CZ2-CE 4.48Å; W294-M299 HydrophobicContact CZ3-CE 3.74Å; W294-I353 WeakPolarHBondContact CH2-O 3.43Å; W294-C356 HydrophobicContact CH2-CB 4.34Å; W294-L362 HydrophobicContact CE3-CD2 4.45Å; W294-L362 HydrophobicContact CH2-CD1 4.46Å; W294-L362 HydrophobicContact CZ3-CD1 3.88Å; W294-L362 HydrophobicContact CZ3-CD2 3.8Å; W294-L362 HydrophobicContact CZ3-CG 4.45Å; W294-F427 HydrophobicContact CB-CD1 4.19Å; W294-F427 HydrophobicContact CB-CD2 3.86Å; W294-F427 HydrophobicContact CB-CE1 4.31Å; W294-F427 HydrophobicContact CB-CE2 4.03Å; W294-F427 HydrophobicContact CB-CG 3.95Å; W294-F427 HydrophobicContact CB-CZ 4.24Å; W294-F427 AromaticContact CD1-CD1 3.34Å; W294-F427 AromaticContact CD1-CG 3.49Å; W294-F427 VanDerWaalsContact CD1-CG 3.49Å; W294-F427 AromaticContact CD2-CD1 3.56Å; W294-F427 HydrophobicContact CD2-CD1 3.56Å; W294-F427 AromaticContact CD2-CE1 3.39Å; W294-F427 HydrophobicContact CD2-CE1 3.39Å; W294-F427 HydrophobicContact CD2-CG 4.23Å; W294-F427 AromaticContact CD2-CZ 3.97Å; W294-F427 HydrophobicContact CD2-CZ 3.97Å; W294-F427 AromaticContact CE2-CD1 3.55Å; W294-F427 AromaticContact CE2-CE1 3.65Å; W294-F427 HydrophobicContact CE3-CD1 4.34Å; W294-F427 AromaticContact CE3-CE1 3.7Å; W294-F427 HydrophobicContact CE3-CE1 3.7Å; W294-F427 HydrophobicContact CE3-CZ 4.01Å; W294-F427 HydrophobicContact CG-CB 4.17Å; W294-F427 AromaticContact CG-CD1 3.44Å; W294-F427 HydrophobicContact CG-CD1 3.44Å; W294-F427 VanDerWaalsContact CG-CD1 3.44Å; W294-F427 HydrophobicContact CG-CD2 4.02Å; W294-F427 AromaticContact CG-CE1 3.67Å; W294-F427 HydrophobicContact CG-CE1 3.67Å; W294-F427 HydrophobicContact CG-CE2 4.24Å; W294-F427 AromaticContact CG-CG 3.61Å; W294-F427 HydrophobicContact CG-CG 3.61Å; W294-F427 HydrophobicContact CG-CZ 4.07Å; W294-F427 HydrophobicContact CH2-CE1 4.39Å; W294-F427 HydrophobicContact CZ2-CD1 4.31Å; W294-F427 HydrophobicContact CZ2-CE1 4.16Å; W294-F427 HydrophobicContact CZ3-CE1 4.18Å; W294-F427 AromaticContact NE1-CD1 3.4Å
295	M	88.3	Confident	85.7	Confident	0 Å²	0	51 Å²	51	0%	0	28%	0.279	C	S	.	.	H	α-helix	trans	-62.7	-43.5	176.3	-73.8	176.1	60.7	0	0	111.8	I291 S292 K297 M299 K300 A301 E306 V309 F359 L362	I291-M295 HydrophobicContact CD1-SD 4.42Å; I291-M295 HydrophobicContact CG1-CG 4.16Å; I291-M295 HydrophobicContact CG1-SD 4Å; I291-M295 WeakPolarHBondContact O-CB 3.43Å; I291-M295 VanDerWaalsContact O-CG 3.3Å; I291-M295 WeakPolarHBondContact O-CG 3.46Å; I291-M295 PolarHBondContact O-N 3.18Å; S292-M295 PolarHBondContact O-N 3.05Å; M295-K297 PolarHBondContact O-N 2.74Å; M295-M299 CarbonylContact O-C 3.55Å; M295-M299 WeakPolarHBondContact O-CA 3.23Å; M295-M299 WeakPolarHBondContact O-CB 3.46Å; M295-M299 PolarHBondContact O-N 3.09Å; M295-K300 PolarHBondContact O-N 2.97Å; M295-A301 HydrophobicContact CB-CB 3.83Å; M295-A301 HydrophobicContact CE-CB 3.98Å; M295-A301 PolarHBondContact O-N 2.96Å; M295-E306 HydrophobicContact CB-CG 4.22Å; M295-E306 HydrophobicContact CE-CB 4.48Å; M295-E306 HydrophobicContact CE-CG 4.14Å; M295-E306 HydrophobicContact SD-CG 4.45Å; M295-V309 HydrophobicContact CE-CB 4.19Å; M295-V309 HydrophobicContact CE-CG2 4.29Å; M295-V309 HydrophobicContact SD-CB 4.26Å; M295-V309 HydrophobicContact SD-CG1 4.13Å; M295-V309 HydrophobicContact SD-CG2 4.27Å; M295-F359 HydrophobicContact CE-CD2 3.63Å; M295-F359 HydrophobicContact CE-CE2 4.25Å; M295-L362 HydrophobicContact CE-CD2 4.28Å; M295-L362 HydrophobicContact CG-CD2 3.58Å; M295-L362 HydrophobicContact SD-CD2 3.56Å; M295-L362 VanDerWaalsContact SD-CD2 3.56Å
296	S	85.2	Confident	85.2	Confident	59 Å²	59	52.1 Å²	52.1	41%	0.413	28%	0.284	S	S	.	.	H	α-helix	trans	-59.3	-44.8	175.3	-167.3	0	0	0	0	111.9	S292 K300 E306	S292-S296 WeakPolarHBondContact O-CB 3.45Å; S292-S296 PolarHBondContact O-N 3.15Å; S296-K300 VanDerWaalsContact O-CA 3.28Å; S296-K300 WeakPolarHBondContact O-CA 3.37Å; S296-K300 PolarHBondContact O-N 3.29Å; S296-E306 WeakPolarHBondContact CB-OE1 3.4Å
297	K	86.8	Confident	84.6	Confident	142 Å²	142	53.7 Å²	53.7	62%	0.617	30%	0.304	S	S	*	.	H	α-helix	trans	-75.9	-45.5	-178.6	-73.6	173.4	177.9	164.9	0	113.6	N293 W294 M295	N293-K297 PolarHBondContact ND2-NZ 2.94Å; N293-K297 WeakPolarHBondContact O-CB 3.43Å; N293-K297 WeakPolarHBondContact O-CG 3.43Å; N293-K297 PolarHBondContact O-N 3.28Å; N293-K297 VanDerWaalsContact O-N 3.15Å; N293-K297 WeakPolarHBondContact OD1-CE 3.44Å; N293-K297 PolarHBondContact OD1-NZ 3.25Å; W294-K297 PolarHBondContact O-N 2.83Å; M295-K297 PolarHBondContact O-N 2.74Å
298	S	88.4	Confident	84.3	Confident	71 Å²	71	57.5 Å²	57.5	50%	0.497	32%	0.324	S	S	.	.	H	α-helix	trans	-88.5	-31.6	-170	-55.2	0	0	0	0	112.9	W294	W294-S298 PolarHBondContact NE1-OG 3.4Å; W294-S298 WeakPolarHBondContact O-CB 3.46Å; W294-S298 PolarHBondContact O-N 2.97Å; W294-S298 PolarHBondContact O-OG 3.49Å; W294-S298 VanDerWaalsContact O-OG 3.07Å
299	M	88.6	Confident	84.5	Confident	36 Å²	36	55.8 Å²	55.8	18%	0.177	32%	0.316	C	S	.	.	H	α-helix	trans	-118.4	-3.9	-174.7	-55.7	179.8	173.9	0	0	113.5	W294 M295 A301 C356 L362	W294-M299 HydrophobicContact CH2-CE 3.56Å; W294-M299 HydrophobicContact CZ2-CE 4.48Å; W294-M299 HydrophobicContact CZ3-CE 3.74Å; M295-M299 CarbonylContact O-C 3.55Å; M295-M299 WeakPolarHBondContact O-CA 3.23Å; M295-M299 WeakPolarHBondContact O-CB 3.46Å; M295-M299 PolarHBondContact O-N 3.09Å; M299-A301 PolarHBondContact O-N 3.23Å; M299-C356 HydrophobicContact CE-CB 3.93Å; M299-C356 WeakPolarHBondContact CE-O 3.41Å; M299-L362 HydrophobicContact CE-CB 4.37Å; M299-L362 HydrophobicContact CE-CD2 4.4Å; M299-L362 HydrophobicContact SD-CD2 4.48Å
300	K	86.9	Confident	84.8	Confident	190 Å²	190	56 Å²	56	83%	0.826	31%	0.309	S	S	*	.			trans	52.6	38.8	-171	-57.7	179	-179.3	176.5	0	111.8	M295 S296	M295-K300 PolarHBondContact O-N 2.97Å; S296-K300 VanDerWaalsContact O-CA 3.28Å; S296-K300 WeakPolarHBondContact O-CA 3.37Å; S296-K300 PolarHBondContact O-N 3.29Å
301	A	82.3	Confident	84.8	Confident	9 Å²	9	58.6 Å²	58.6	7%	0.074	32%	0.322	C	S	.	.			trans	-63.8	149.1	-177.8	0	0	0	0	0	111.6	M295 M299 Q305 E306	M295-A301 HydrophobicContact CB-CB 3.83Å; M295-A301 HydrophobicContact CE-CB 3.98Å; M295-A301 PolarHBondContact O-N 2.96Å; M299-A301 PolarHBondContact O-N 3.23Å; A301-Q305 HydrophobicContact CB-CB 4.22Å; A301-E306 HydrophobicContact CB-CG 4.24Å
302	T	82.4	Confident	84.8	Confident	74 Å²	74	60.3 Å²	60.3	45%	0.454	33%	0.333	S	S	.	.			trans	-82.2	156.9	170.8	66.1	0	0	0	0	110.6	A304 Q305 E306	T302-A304 PolarHBondContact O-N 3.17Å; T302-A304 VanDerWaalsContact O-N 3.11Å; T302-Q305 WeakPolarHBondContact O-CA 3.2Å; T302-Q305 WeakPolarHBondContact O-CB 3.46Å; T302-Q305 PolarHBondContact O-N 3.41Å; T302-Q305 WeakPolarHBondContact OG1-CG 3.44Å; T302-Q305 PolarHBondContact OG1-N 2.94Å; T302-E306 PolarHBondContact O-N 3.32Å
303	N	75.5	Confident	85.2	Confident	127 Å²	127	58.9 Å²	58.9	68%	0.679	32%	0.324	S	S	*	.	H	α-helix	trans	-54.3	-33.7	175.1	-59.6	0.3	0	0	0	112.4	G307	N303-G307 PolarHBondContact O-N 3.03Å
304	A	75.3	Confident	85.6	Confident	61 Å²	61	58.2 Å²	58.2	50%	0.504	32%	0.318	S	S	.	.	H	α-helix	trans	-66.2	-43.7	174.8	0	0	0	0	0	111.5	T302 G307 L308	T302-A304 PolarHBondContact O-N 3.17Å; T302-A304 VanDerWaalsContact O-N 3.11Å; A304-G307 PolarHBondContact O-N 3.25Å; A304-L308 WeakPolarHBondContact O-CB 3.48Å; A304-L308 WeakPolarHBondContact O-CG 3.27Å; A304-L308 PolarHBondContact O-N 2.84Å
305	Q	84.4	Confident	85.8	Confident	68 Å²	68	62.6 Å²	62.6	32%	0.318	34%	0.344	S	S	.	.	H	α-helix	trans	-63.1	-42	175.5	-72.6	169	-25.7	0	0	111.5	A301 T302 G307 L308 V309 F359	A301-Q305 HydrophobicContact CB-CB 4.22Å; T302-Q305 WeakPolarHBondContact O-CA 3.2Å; T302-Q305 WeakPolarHBondContact O-CB 3.46Å; T302-Q305 PolarHBondContact O-N 3.41Å; T302-Q305 WeakPolarHBondContact OG1-CG 3.44Å; T302-Q305 PolarHBondContact OG1-N 2.94Å; Q305-G307 VanDerWaalsContact C-N 3.26Å; Q305-G307 PolarHBondContact O-N 3.13Å; Q305-L308 PolarHBondContact O-N 2.89Å; Q305-V309 PolarHBondContact O-N 3.24Å; Q305-V309 VanDerWaalsContact O-N 3.09Å; Q305-F359 HydrophobicContact CB-CD1 4.48Å; Q305-F359 HydrophobicContact CB-CD2 3.89Å; Q305-F359 HydrophobicContact CB-CE2 4.06Å; Q305-F359 HydrophobicContact CB-CG 4.11Å; Q305-F359 HydrophobicContact CB-CZ 4.43Å; Q305-F359 HydrophobicContact CG-CD1 4.18Å; Q305-F359 HydrophobicContact CG-CD2 4.46Å; Q305-F359 HydrophobicContact CG-CE1 4.37Å; Q305-F359 HydrophobicContact CG-CG 4.22Å; Q305-F359 WeakPolarHBondContact O-CE2 3.46Å
306	E	80.5	Confident	86.2	Confident	23 Å²	23	64 Å²	64	11%	0.107	35%	0.352	C	S	.	.	H	α-helix	trans	-57.5	-37.4	176.4	-67.5	173	-170.2	0	0	112.9	S292 M295 S296 A301 T302 V309	S292-E306 WeakPolarHBondContact CB-OE2 3.05Å; M295-E306 HydrophobicContact CB-CG 4.22Å; M295-E306 HydrophobicContact CE-CB 4.48Å; M295-E306 HydrophobicContact CE-CG 4.14Å; M295-E306 HydrophobicContact SD-CG 4.45Å; S296-E306 WeakPolarHBondContact CB-OE1 3.4Å; A301-E306 HydrophobicContact CB-CG 4.24Å; T302-E306 PolarHBondContact O-N 3.32Å; E306-V309 WeakPolarHBondContact O-CG1 3.47Å
307	G	79.7	Confident	86.8	Confident	46 Å²	46	62 Å²	62	47%	0.474	34%	0.337	S	S	.	.	H	α-helix	trans	-76.8	-43.1	173.7	0	0	0	0	0	113.8	N303 A304 Q305 V309 W310	N303-G307 PolarHBondContact O-N 3.03Å; A304-G307 PolarHBondContact O-N 3.25Å; Q305-G307 VanDerWaalsContact C-N 3.26Å; Q305-G307 PolarHBondContact O-N 3.13Å; G307-V309 PolarHBondContact O-N 3.38Å; G307-W310 PolarHBondContact O-N 3.43Å
308	L	85.5	Confident	87.2	Confident	85 Å²	85	56.9 Å²	56.9	45%	0.445	32%	0.317	S	S	.	.	H	α-helix	trans	-66.2	-17.9	-177.2	-71.1	173.1	0	0	0	113.2	A304 Q305 W310 L311 P312 F359	A304-L308 WeakPolarHBondContact O-CB 3.48Å; A304-L308 WeakPolarHBondContact O-CG 3.27Å; A304-L308 PolarHBondContact O-N 2.84Å; Q305-L308 PolarHBondContact O-N 2.89Å; L308-W310 PolarHBondContact O-N 3.01Å; L308-L311 HydrophobicContact CD2-CD1 3.39Å; L308-L311 HydrophobicContact CD2-CG 4.35Å; L308-L311 PolarHBondContact O-N 3.29Å; L308-P312 WeakPolarHBondContact O-CD 3.35Å; L308-F359 HydrophobicContact CB-CE2 4.38Å; L308-F359 HydrophobicContact CB-CZ 3.74Å
309	V	89.1	Confident	87.7	Confident	1 Å²	1	55.4 Å²	55.4	1%	0.006	31%	0.309	C	S	.	.	T	Hydrogen-bonded Turn	trans	-61.6	-29.2	-178.7	84.4	0	0	0	0	112.4	M295 Q305 E306 G307 P312 F359 L362 M363 I366	M295-V309 HydrophobicContact CE-CB 4.19Å; M295-V309 HydrophobicContact CE-CG2 4.29Å; M295-V309 HydrophobicContact SD-CB 4.26Å; M295-V309 HydrophobicContact SD-CG1 4.13Å; M295-V309 HydrophobicContact SD-CG2 4.27Å; Q305-V309 PolarHBondContact O-N 3.24Å; Q305-V309 VanDerWaalsContact O-N 3.09Å; E306-V309 WeakPolarHBondContact O-CG1 3.47Å; G307-V309 PolarHBondContact O-N 3.38Å; V309-P312 WeakPolarHBondContact O-CD 3.17Å; V309-F359 VanDerWaalsContact CA-CE2 3.49Å; V309-F359 HydrophobicContact CB-CD2 4.15Å; V309-F359 HydrophobicContact CB-CE2 3.57Å; V309-F359 HydrophobicContact CG2-CD2 3.99Å; V309-F359 HydrophobicContact CG2-CE2 3.79Å; V309-L362 HydrophobicContact CG2-CB 4.34Å; V309-L362 HydrophobicContact CG2-CD2 3.89Å; V309-L362 HydrophobicContact CG2-CG 3.96Å; V309-M363 HydrophobicContact CG2-CG 4.05Å; V309-I366 HydrophobicContact CB-CD1 4.4Å; V309-I366 HydrophobicContact CG1-CD1 4Å; V309-I366 HydrophobicContact CG2-CD1 3.62Å
310	W	87.8	Confident	88.2	Confident	65 Å²	65	53.7 Å²	53.7	25%	0.246	30%	0.301	C	S	.	.	S	Bend	trans	-85.1	-26.3	-175.7	-63.9	110	0	0	0	113.5	L284 L287 E288 I291 G307 L308 P312 A313 I366	L284-W310 HydrophobicContact CD1-CE3 4.47Å; L284-W310 HydrophobicContact CD1-CH2 3.76Å; L284-W310 HydrophobicContact CD1-CZ3 3.46Å; L284-W310 VanDerWaalsContact CD1-CZ3 3.46Å; L287-W310 HydrophobicContact CB-CH2 4.38Å; L287-W310 HydrophobicContact CD2-CH2 3.76Å; L287-W310 HydrophobicContact CD2-CZ3 4.25Å; L287-W310 HydrophobicContact CG-CH2 3.88Å; E288-W310 HydrophobicContact CG-CH2 4.13Å; E288-W310 HydrophobicContact CG-CZ2 4.12Å; I291-W310 HydrophobicContact CB-CZ2 4.5Å; I291-W310 HydrophobicContact CD1-CZ2 4.37Å; I291-W310 HydrophobicContact CG2-CZ2 3.54Å; G307-W310 PolarHBondContact O-N 3.43Å; L308-W310 PolarHBondContact O-N 3.01Å; W310-P312 VanDerWaalsContact C-CD 3.47Å; W310-A313 WeakPolarHBondContact O-CB 3.33Å; W310-A313 PolarHBondContact O-N 3.45Å; W310-A313 VanDerWaalsContact O-N 3.11Å; W310-I366 HydrophobicContact CE3-CG2 3.57Å; W310-I366 HydrophobicContact CZ3-CG2 3.55Å
311	L	86.6	Confident	88.7	Confident	63 Å²	63	44.9 Å²	44.9	33%	0.33	26%	0.263	S	S	.	.	G	3₁₀ helix	trans	-56.5	-44.5	-174.8	-64.5	-176.9	0	0	0	114	L202 L308 A313 F314	L202-L311 HydrophobicContact CD1-CB 4.31Å; L202-L311 HydrophobicContact CD1-CD2 3.55Å; L308-L311 HydrophobicContact CD2-CD1 3.39Å; L308-L311 HydrophobicContact CD2-CG 4.35Å; L308-L311 PolarHBondContact O-N 3.29Å; L311-A313 PolarHBondContact O-N 2.97Å; L311-F314 PolarHBondContact O-N 2.85Å
312	P	90.3	Very high	89.4	Confident	35 Å²	35	48.3 Å²	48.3	23%	0.227	28%	0.279	C	S	.	.	G	3₁₀ helix	trans	-62.7	-32.3	-179.7	-19.5	30.9	0	0	0	112.6	L308 V309 W310 F314 L315 P316 M363	L308-P312 WeakPolarHBondContact O-CD 3.35Å; V309-P312 WeakPolarHBondContact O-CD 3.17Å; W310-P312 VanDerWaalsContact C-CD 3.47Å; P312-F314 PolarHBondContact O-N 3.02Å; P312-F314 VanDerWaalsContact O-N 3.16Å; P312-L315 PolarHBondContact O-N 2.99Å; P312-L315 VanDerWaalsContact O-N 3.15Å; P312-P316 WeakPolarHBondContact O-CD 3.47Å; P312-M363 HydrophobicContact CB-CE 4.23Å; P312-M363 HydrophobicContact CG-CB 4.09Å; P312-M363 HydrophobicContact CG-CE 3.05Å; P312-M363 HydrophobicContact CG-CG 3.97Å; P312-M363 HydrophobicContact CG-SD 4.28Å
313	A	93.2	Very high	90.2	Very high	4 Å²	4	46.9 Å²	46.9	3%	0.033	27%	0.271	C	S	.	.	G	3₁₀ helix	trans	-65.9	-19.3	-172.2	0	0	0	0	0	113.4	W310 L311 P316 H317 I366 C370	W310-A313 WeakPolarHBondContact O-CB 3.33Å; W310-A313 PolarHBondContact O-N 3.45Å; W310-A313 VanDerWaalsContact O-N 3.11Å; L311-A313 PolarHBondContact O-N 2.97Å; A313-P316 WeakPolarHBondContact O-CD 3.19Å; A313-H317 WeakPolarHBondContact O-CB 3.47Å; A313-H317 PolarHBondContact O-N 3.04Å; A313-I366 HydrophobicContact CB-CG2 3.82Å; A313-C370 HydrophobicContact CB-CB 4.05Å
314	F	91.2	Very high	91.3	Very high	34 Å²	34	40.9 Å²	40.9	15%	0.149	24%	0.238	C	C	.	.	H	α-helix	trans	-57.8	-48	170.5	168	-99.4	0	0	0	113	S198 F199 L202 L311 P312 H317 V318	S198-F314 VanDerWaalsContact O-CD2 3.28Å; S198-F314 WeakPolarHBondContact O-CD2 3.25Å; F199-F314 VanDerWaalsContact CA-CE2 3.42Å; F199-F314 HydrophobicContact CB-CE2 3.87Å; F199-F314 HydrophobicContact CB-CZ 4.24Å; F199-F314 HydrophobicContact CD2-CE2 4.23Å; F199-F314 AromaticContact CD2-CZ 3.88Å; F199-F314 HydrophobicContact CD2-CZ 3.88Å; L202-F314 HydrophobicContact CB-CB 4.26Å; L202-F314 HydrophobicContact CB-CD2 3.93Å; L202-F314 HydrophobicContact CB-CE2 4.48Å; L202-F314 HydrophobicContact CB-CG 3.99Å; L202-F314 HydrophobicContact CD1-CB 4.16Å; L202-F314 HydrophobicContact CD1-CG 4.41Å; L202-F314 HydrophobicContact CD2-CB 4.35Å; L202-F314 HydrophobicContact CD2-CD1 3.47Å; L202-F314 VanDerWaalsContact CD2-CD1 3.47Å; L202-F314 HydrophobicContact CD2-CD2 4.22Å; L202-F314 HydrophobicContact CD2-CE1 3.71Å; L202-F314 HydrophobicContact CD2-CE2 4.46Å; L202-F314 HydrophobicContact CD2-CG 3.73Å; L202-F314 HydrophobicContact CD2-CZ 4.2Å; L202-F314 HydrophobicContact CG-CB 4.49Å; L202-F314 HydrophobicContact CG-CD1 4.44Å; L202-F314 HydrophobicContact CG-CG 4.25Å; L311-F314 PolarHBondContact O-N 2.85Å; P312-F314 PolarHBondContact O-N 3.02Å; P312-F314 VanDerWaalsContact O-N 3.16Å; F314-H317 WeakPolarHBondContact O-CB 3.43Å; F314-H317 PolarHBondContact O-N 2.97Å; F314-V318 HydrophobicContact CD2-CG2 4.14Å; F314-V318 HydrophobicContact CE1-CG2 4.11Å; F314-V318 HydrophobicContact CE2-CG2 3.52Å; F314-V318 HydrophobicContact CZ-CG2 3.53Å; F314-V318 PolarHBondContact O-N 3.32Å
315	L	94	Very high	92.4	Very high	122 Å²	122	38.9 Å²	38.9	64%	0.639	22%	0.219	S	C	*	.	H	α-helix	trans	-64.6	-46.8	-175.3	-66.1	175.1	0	0	0	112.1	P312 V318 A319	P312-L315 PolarHBondContact O-N 2.99Å; P312-L315 VanDerWaalsContact O-N 3.15Å; L315-V318 PolarHBondContact O-N 3.43Å; L315-A319 WeakPolarHBondContact O-CB 3.38Å; L315-A319 PolarHBondContact O-N 3.01Å
316	P	96.9	Very high	93	Very high	28 Å²	28	42.7 Å²	42.7	18%	0.182	23%	0.234	C	C	.	.	H	α-helix	trans	-57.6	-40.8	168.2	-22.3	30.2	0	0	0	113.4	P312 A313 V318 A319 G320 S367 Y371	P312-P316 WeakPolarHBondContact O-CD 3.47Å; A313-P316 WeakPolarHBondContact O-CD 3.19Å; P316-V318 PolarHBondContact O-N 2.89Å; P316-A319 CarbonylContact O-C 3.57Å; P316-A319 WeakPolarHBondContact O-CB 3.45Å; P316-A319 PolarHBondContact O-N 3.18Å; P316-G320 PolarHBondContact O-N 2.91Å; P316-S367 WeakPolarHBondContact CB-O 3.31Å; P316-Y371 VanDerWaalsContact O-CD2 3.26Å; P316-Y371 WeakPolarHBondContact O-CD2 3.48Å
317	H	97.1	Very high	93.8	Very high	19 Å²	19	44.8 Å²	44.8	9%	0.088	25%	0.246	C	C	.	.	H	α-helix	trans	-59.5	-50.6	176.5	-174.6	-72.5	0	0	0	111.1	S198 A313 F314 A319 G320 V321 C370 A374	S198-H317 PolarHBondContact OG-CE1 3.33Å; S198-H317 VanDerWaalsContact OG-CG 3.23Å; S198-H317 PolarHBondContact OG-ND1 3.44Å; A313-H317 WeakPolarHBondContact O-CB 3.47Å; A313-H317 PolarHBondContact O-N 3.04Å; F314-H317 WeakPolarHBondContact O-CB 3.43Å; F314-H317 PolarHBondContact O-N 2.97Å; H317-A319 VanDerWaalsContact C-N 3.3Å; H317-A319 PolarHBondContact O-N 3.31Å; H317-G320 WeakPolarHBondContact O-CA 2.82Å; H317-G320 PolarHBondContact O-N 3.29Å; H317-V321 PolarHBondContact O-N 2.97Å; H317-C370 HydrophobicContact CB-CB 4.18Å; H317-C370 PolarHBondContact CD2-O 2.85Å; H317-A374 HydrophobicContact CB-CB 4.49Å; H317-A374 WeakPolarHBondContact O-CB 3.32Å
318	V	96.5	Very high	94.5	Very high	33 Å²	33	42.7 Å²	42.7	20%	0.2	23%	0.225	C	C	.	.	H	α-helix	trans	-61	-39.9	175.7	174.4	0	0	0	0	111.6	A195 F314 L315 P316 G320 V321 I322	A195-V318 HydrophobicContact CB-CG2 4.49Å; F314-V318 HydrophobicContact CD2-CG2 4.14Å; F314-V318 HydrophobicContact CE1-CG2 4.11Å; F314-V318 HydrophobicContact CE2-CG2 3.52Å; F314-V318 HydrophobicContact CZ-CG2 3.53Å; F314-V318 PolarHBondContact O-N 3.32Å; L315-V318 PolarHBondContact O-N 3.43Å; P316-V318 PolarHBondContact O-N 2.89Å; V318-G320 VanDerWaalsContact C-N 3.3Å; V318-G320 PolarHBondContact O-N 2.92Å; V318-V321 PolarHBondContact O-N 2.97Å; V318-I322 HydrophobicContact CG1-CD1 3.94Å; V318-I322 WeakPolarHBondContact O-CG1 3.47Å; V318-I322 PolarHBondContact O-N 3.19Å
319	A	97.7	Very high	95	Very high	41 Å²	41	43 Å²	43	34%	0.339	23%	0.226	S	C	.	.	H	α-helix	trans	-61	-39.9	174	0	0	0	0	0	111.5	L315 P316 H317 I322 T323 Y371	L315-A319 WeakPolarHBondContact O-CB 3.38Å; L315-A319 PolarHBondContact O-N 3.01Å; P316-A319 CarbonylContact O-C 3.57Å; P316-A319 WeakPolarHBondContact O-CB 3.45Å; P316-A319 PolarHBondContact O-N 3.18Å; H317-A319 VanDerWaalsContact C-N 3.3Å; H317-A319 PolarHBondContact O-N 3.31Å; A319-I322 PolarHBondContact O-N 2.92Å; A319-T323 WeakPolarHBondContact O-CB 3.46Å; A319-T323 PolarHBondContact O-N 3.35Å; A319-T323 PolarHBondContact O-OG1 2.86Å; A319-Y371 HydrophobicContact CB-CE2 4.44Å
320	G	98.4	Very high	95.3	Very high	0 Å²	0	49.8 Å²	49.8	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-64.1	-42.8	176.1	0	0	0	0	0	112.7	P316 H317 V318 I322 T323 T324 Y371 L375	P316-G320 PolarHBondContact O-N 2.91Å; H317-G320 WeakPolarHBondContact O-CA 2.82Å; H317-G320 PolarHBondContact O-N 3.29Å; V318-G320 VanDerWaalsContact C-N 3.3Å; V318-G320 PolarHBondContact O-N 2.92Å; G320-I322 PolarHBondContact O-N 3.24Å; G320-T323 PolarHBondContact O-N 3.08Å; G320-T324 WeakPolarHBondContact O-CB 3.49Å; G320-T324 PolarHBondContact O-N 2.75Å; G320-T324 PolarHBondContact O-OG1 3.43Å; G320-Y371 VanDerWaalsContact CA-CE2 3.41Å; G320-L375 VanDerWaalsContact CA-CD1 3.46Å
321	V	98.3	Very high	95.6	Very high	4 Å²	4	51.8 Å²	51.8	2%	0.024	26%	0.264	C	S	.	.	H	α-helix	trans	-56.4	-51.8	170.8	172.8	0	0	0	0	110.3	G191 L194 H317 V318 T323 T324 I325 A374 T378	G191-V321 WeakPolarHBondContact O-CG1 3.35Å; L194-V321 HydrophobicContact CB-CG2 4.45Å; H317-V321 PolarHBondContact O-N 2.97Å; V318-V321 PolarHBondContact O-N 2.97Å; V321-T323 PolarHBondContact O-N 3.48Å; V321-T324 PolarHBondContact O-N 3.49Å; V321-I325 HydrophobicContact CG1-CD1 3.81Å; V321-I325 WeakPolarHBondContact O-CG1 3.44Å; V321-I325 PolarHBondContact O-N 3.13Å; V321-A374 HydrophobicContact CG2-CB 4.12Å; V321-T378 HydrophobicContact CG1-CG2 4.37Å
322	I	97.9	Very high	95.8	Very high	81 Å²	81	51.7 Å²	51.7	42%	0.415	27%	0.268	S	S	.	.	H	α-helix	trans	-62.6	-42.9	-179	-66.9	167.3	0	0	0	111.3	V318 A319 G320 T324 I325 K326	V318-I322 HydrophobicContact CG1-CD1 3.94Å; V318-I322 WeakPolarHBondContact O-CG1 3.47Å; V318-I322 PolarHBondContact O-N 3.19Å; A319-I322 PolarHBondContact O-N 2.92Å; G320-I322 PolarHBondContact O-N 3.24Å; I322-T324 VanDerWaalsContact C-N 3.32Å; I322-T324 PolarHBondContact O-N 3.07Å; I322-I325 PolarHBondContact O-N 2.85Å; I322-K326 HydrophobicContact CG2-CD 4.18Å; I322-K326 WeakPolarHBondContact O-CG 3.4Å; I322-K326 PolarHBondContact O-N 3.16Å
323	T	98.2	Very high	95.8	Very high	45 Å²	45	52.4 Å²	52.4	28%	0.276	27%	0.273	S	S	.	.	H	α-helix	trans	-59.6	-46.1	176.6	-65.8	0	0	0	0	110.4	A319 G320 V321 K326 L327 Y371	A319-T323 WeakPolarHBondContact O-CB 3.46Å; A319-T323 PolarHBondContact O-N 3.35Å; A319-T323 PolarHBondContact O-OG1 2.86Å; G320-T323 PolarHBondContact O-N 3.08Å; V321-T323 PolarHBondContact O-N 3.48Å; T323-K326 PolarHBondContact O-N 3.39Å; T323-L327 HydrophobicContact CG2-CD1 3.68Å; T323-L327 HydrophobicContact CG2-CG 4.19Å; T323-L327 WeakPolarHBondContact O-CB 3.35Å; T323-L327 VanDerWaalsContact O-CG 3.29Å; T323-L327 WeakPolarHBondContact O-CG 3.38Å; T323-L327 PolarHBondContact O-N 3.28Å; T323-Y371 WeakPolarHBondContact CG2-OH 3.41Å; T323-Y371 PolarHBondContact OG1-OH 3.36Å
324	T	98.4	Very high	95.8	Very high	0 Å²	0	56.5 Å²	56.5	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-65.4	-43.9	-178.1	-53.8	0	0	0	0	111.6	G320 V321 I322 K326 L327 A328 M338 L375 T378 A379	G320-T324 WeakPolarHBondContact O-CB 3.49Å; G320-T324 PolarHBondContact O-N 2.75Å; G320-T324 PolarHBondContact O-OG1 3.43Å; V321-T324 PolarHBondContact O-N 3.49Å; I322-T324 VanDerWaalsContact C-N 3.32Å; I322-T324 PolarHBondContact O-N 3.07Å; T324-K326 PolarHBondContact O-N 3.49Å; T324-L327 PolarHBondContact O-N 3.09Å; T324-A328 VanDerWaalsContact O-CB 3.25Å; T324-A328 WeakPolarHBondContact O-CB 3.4Å; T324-A328 PolarHBondContact O-N 3.28Å; T324-M338 HydrophobicContact CG2-SD 4.21Å; T324-L375 WeakPolarHBondContact OG1-CA 3.34Å; T324-T378 HydrophobicContact CG2-CG2 3.76Å; T324-A379 HydrophobicContact CG2-CB 3.94Å
325	I	97.9	Very high	96	Very high	20 Å²	20	55 Å²	55	10%	0.103	28%	0.284	C	S	.	.	H	α-helix	trans	-59.1	-46.9	175.3	-66.2	166.9	0	0	0	110.8	Y184 K188 V321 I322 L327 A328 D329 T378	Y184-I325 HydrophobicContact CE2-CG2 4.09Å; K188-I325 HydrophobicContact CB-CG2 4.2Å; K188-I325 HydrophobicContact CG-CG2 4.32Å; V321-I325 HydrophobicContact CG1-CD1 3.81Å; V321-I325 WeakPolarHBondContact O-CG1 3.44Å; V321-I325 PolarHBondContact O-N 3.13Å; I322-I325 PolarHBondContact O-N 2.85Å; I325-L327 VanDerWaalsContact C-N 3.35Å; I325-L327 PolarHBondContact O-N 2.98Å; I325-A328 PolarHBondContact O-N 3.15Å; I325-D329 PolarHBondContact O-N 2.89Å; I325-T378 HydrophobicContact CG1-CG2 4.06Å
326	K	97.7	Very high	96.1	Very high	147 Å²	147	50.4 Å²	50.4	64%	0.639	26%	0.258	S	S	*	.	H	α-helix	trans	-64.5	-38.2	179.3	-74.1	-180	177.6	-179.4	0	112.6	I322 T323 T324 D329 K330	I322-K326 HydrophobicContact CG2-CD 4.18Å; I322-K326 WeakPolarHBondContact O-CG 3.4Å; I322-K326 PolarHBondContact O-N 3.16Å; T323-K326 PolarHBondContact O-N 3.39Å; T324-K326 PolarHBondContact O-N 3.49Å; K326-D329 WeakPolarHBondContact O-CB 3.38Å; K326-K330 PolarHBondContact O-N 3.4Å
327	L	97.2	Very high	96.1	Very high	67 Å²	67	52.7 Å²	52.7	35%	0.351	27%	0.268	S	S	.	.	H	α-helix	trans	-71.4	-36.9	176.7	-71.6	175.4	0	0	0	111.6	T323 T324 I325 D329 K330 Y331 M338	T323-L327 HydrophobicContact CG2-CD1 3.68Å; T323-L327 HydrophobicContact CG2-CG 4.19Å; T323-L327 WeakPolarHBondContact O-CB 3.35Å; T323-L327 VanDerWaalsContact O-CG 3.29Å; T323-L327 WeakPolarHBondContact O-CG 3.38Å; T323-L327 PolarHBondContact O-N 3.28Å; T324-L327 PolarHBondContact O-N 3.09Å; I325-L327 VanDerWaalsContact C-N 3.35Å; I325-L327 PolarHBondContact O-N 2.98Å; L327-D329 VanDerWaalsContact C-N 3.33Å; L327-K330 PolarHBondContact O-N 2.88Å; L327-Y331 WeakPolarHBondContact O-CA 3.37Å; L327-Y331 PolarHBondContact O-N 2.88Å; L327-M338 VanDerWaalsContact C-CE 3.43Å; L327-M338 HydrophobicContact CB-CE 3.73Å; L327-M338 HydrophobicContact CB-CG 4.46Å; L327-M338 HydrophobicContact CB-SD 3.75Å; L327-M338 WeakPolarHBondContact O-CE 3.36Å
328	A	95.4	Very high	96.2	Very high	3 Å²	3	52.5 Å²	52.5	3%	0.025	27%	0.268	C	S	.	.	H	α-helix	trans	-67.4	-31.8	176.7	0	0	0	0	0	112.7	T187 T324 I325 P332 Q335 M338	T187-A328 HydrophobicContact CG2-CB 3.81Å; T324-A328 VanDerWaalsContact O-CB 3.25Å; T324-A328 WeakPolarHBondContact O-CB 3.4Å; T324-A328 PolarHBondContact O-N 3.28Å; I325-A328 PolarHBondContact O-N 3.15Å; A328-P332 WeakPolarHBondContact O-CA 3.45Å; A328-P332 WeakPolarHBondContact O-CB 3.33Å; A328-P332 WeakPolarHBondContact O-CD 3.38Å; A328-P332 VanDerWaalsContact O-N 3.17Å; A328-Q335 HydrophobicContact CB-CG 4.45Å; A328-M338 HydrophobicContact CB-SD 4.4Å
329	D	95	Very high	96.2	Very high	90 Å²	90	51 Å²	51	48%	0.481	26%	0.258	S	S	.	.	H	α-helix	trans	-59.2	-48.7	170.3	-154.5	-5.4	0	0	0	111.2	Y184 I325 K326 L327	Y184-D329 HydrophobicContact CD2-CB 3.85Å; Y184-D329 HydrophobicContact CE2-CB 3.33Å; Y184-D329 VanDerWaalsContact CZ-OD2 3.23Å; Y184-D329 PolarHBondContact OH-OD2 3.19Å; I325-D329 PolarHBondContact O-N 2.89Å; K326-D329 WeakPolarHBondContact O-CB 3.38Å; L327-D329 VanDerWaalsContact C-N 3.33Å
330	K	95.4	Very high	96.3	Very high	144 Å²	144	49.4 Å²	49.4	63%	0.626	25%	0.245	S	C	*	.	H	α-helix	trans	-80.4	-33.7	-174.6	-167.4	175.4	-179.2	-165.8	0	113.1	K326 L327	K326-K330 PolarHBondContact O-N 3.4Å; L327-K330 PolarHBondContact O-N 2.88Å
331	Y	94.4	Very high	96.2	Very high	107 Å²	107	52.6 Å²	52.6	42%	0.42	27%	0.265	S	S	.	.			trans	-135.7	64.3	-173.6	-53.9	-68.9	0	0	0	111.4	L327 S333 K334 M338	L327-Y331 WeakPolarHBondContact O-CA 3.37Å; L327-Y331 PolarHBondContact O-N 2.88Å; Y331-S333 VanDerWaalsContact C-N 3.26Å; Y331-S333 PolarHBondContact O-N 3.45Å; Y331-K334 PolarHBondContact O-N 3.45Å; Y331-M338 VanDerWaalsContact O-CE 3.29Å; Y331-M338 WeakPolarHBondContact O-CE 3.43Å
332	P	90.6	Very high	96.3	Very high	62 Å²	62	52.4 Å²	52.4	40%	0.403	26%	0.263	S	S	.	.	G	3₁₀ helix	trans	-61.3	-31.9	-174.1	22.6	-33.8	0	0	0	113.4	A328 K334	A328-P332 WeakPolarHBondContact O-CA 3.45Å; A328-P332 WeakPolarHBondContact O-CB 3.33Å; A328-P332 WeakPolarHBondContact O-CD 3.38Å; A328-P332 VanDerWaalsContact O-N 3.17Å; P332-K334 PolarHBondContact O-N 3.43Å
333	S	90.1	Very high	96.3	Very high	50 Å²	50	48.5 Å²	48.5	35%	0.35	24%	0.244	S	C	.	.	G	3₁₀ helix	trans	-77.1	-3.1	178	61.3	0	0	0	0	114.6	Y331	Y331-S333 VanDerWaalsContact C-N 3.26Å; Y331-S333 PolarHBondContact O-N 3.45Å
334	K	94.4	Very high	96.3	Very high	90 Å²	90	48.3 Å²	48.3	39%	0.391	25%	0.246	S	C	.	.	G	3₁₀ helix	trans	-111	17.9	-175.5	-56.6	-57.5	-176	-170.3	0	113.3	Y331 P332 W336 L337 M338	Y331-K334 PolarHBondContact O-N 3.45Å; P332-K334 PolarHBondContact O-N 3.43Å; K334-W336 PolarHBondContact O-N 3.4Å; K334-L337 HydrophobicContact CB-CB 4.38Å; K334-L337 WeakPolarHBondContact O-CA 3.43Å; K334-L337 WeakPolarHBondContact O-CB 3.45Å; K334-L337 PolarHBondContact O-N 3.37Å; K334-M338 HydrophobicContact CB-CE 4.37Å; K334-M338 PolarHBondContact O-N 2.55Å; K334-M338 VanDerWaalsContact O-N 3.15Å
335	Q	94.7	Very high	96.3	Very high	1 Å²	1	50.7 Å²	50.7	1%	0.005	26%	0.259	C	S	.	.	H	α-helix	trans	-56.4	-37.4	176.1	-70.1	-174.1	44.8	0	0	112.5	E183 A328 L337 M338 A339 A379 T383 Y452	E183-Q335 PolarHBondContact OE1-NE2 2.97Å; A328-Q335 HydrophobicContact CB-CG 4.45Å; Q335-L337 PolarHBondContact O-N 2.9Å; Q335-M338 HydrophobicContact CG-SD 4.48Å; Q335-M338 WeakPolarHBondContact O-CB 3.26Å; Q335-M338 PolarHBondContact O-N 3.49Å; Q335-M338 VanDerWaalsContact O-N 3.12Å; Q335-A339 PolarHBondContact O-N 2.97Å; Q335-A379 HydrophobicContact CB-CB 4.26Å; Q335-A379 PolarHBondContact OE1-O 3.3Å; Q335-T383 PolarHBondContact OE1-OG1 3.26Å; Q335-Y452 HydrophobicContact CB-CE2 4.11Å; Q335-Y452 PolarHBondContact NE2-OH 2.8Å; Q335-Y452 PolarHBondContact OE1-OH 3.48Å
336	W	96.1	Very high	96.3	Very high	26 Å²	26	49.8 Å²	49.8	10%	0.098	25%	0.254	C	S	.	.	H	α-helix	trans	-57.3	-35.2	173.5	71.6	-91.2	0	0	0	113.1	K334 A340 Y446 L448 R449	K334-W336 PolarHBondContact O-N 3.4Å; W336-A340 WeakPolarHBondContact O-CB 3.46Å; W336-A340 PolarHBondContact O-N 3.02Å; W336-Y446 AromaticContact CH2-CD2 3.85Å; W336-Y446 HydrophobicContact CH2-CD2 3.85Å; W336-Y446 HydrophobicContact CH2-CE2 4.38Å; W336-Y446 HydrophobicContact CZ3-CD2 4.02Å; W336-L448 HydrophobicContact CB-CB 3.76Å; W336-L448 HydrophobicContact CG-CB 4.48Å; W336-R449 HydrophobicContact CD2-CB 4.23Å; W336-R449 HydrophobicContact CH2-CB 4.33Å; W336-R449 HydrophobicContact CZ2-CB 3.75Å
337	L	97.2	Very high	96.3	Very high	77 Å²	77	42.8 Å²	42.8	40%	0.403	22%	0.223	S	C	.	.	H	α-helix	trans	-75.5	-36.8	179	-178.9	64.6	0	0	0	110.6	K334 Q335 A339 A340 V341	K334-L337 HydrophobicContact CB-CB 4.38Å; K334-L337 WeakPolarHBondContact O-CA 3.43Å; K334-L337 WeakPolarHBondContact O-CB 3.45Å; K334-L337 PolarHBondContact O-N 3.37Å; Q335-L337 PolarHBondContact O-N 2.9Å; L337-A339 VanDerWaalsContact C-N 3.32Å; L337-A339 PolarHBondContact O-N 3.32Å; L337-A340 PolarHBondContact O-N 2.9Å; L337-V341 HydrophobicContact CD1-CG2 4.41Å; L337-V341 HydrophobicContact CG-CG2 4.5Å; L337-V341 WeakPolarHBondContact O-CB 3.49Å; L337-V341 VanDerWaalsContact O-CG2 3.29Å; L337-V341 WeakPolarHBondContact O-CG2 3.44Å; L337-V341 PolarHBondContact O-N 3.11Å
338	M	97.8	Very high	96.3	Very high	15 Å²	15	41.1 Å²	41.1	7%	0.074	22%	0.223	C	C	.	.	H	α-helix	trans	-60.3	-44.7	174.2	-59	171.2	-157.2	0	0	110.6	T324 L327 A328 Y331 K334 Q335 V341 G342 A379	T324-M338 HydrophobicContact CG2-SD 4.21Å; L327-M338 VanDerWaalsContact C-CE 3.43Å; L327-M338 HydrophobicContact CB-CE 3.73Å; L327-M338 HydrophobicContact CB-CG 4.46Å; L327-M338 HydrophobicContact CB-SD 3.75Å; L327-M338 WeakPolarHBondContact O-CE 3.36Å; A328-M338 HydrophobicContact CB-SD 4.4Å; Y331-M338 VanDerWaalsContact O-CE 3.29Å; Y331-M338 WeakPolarHBondContact O-CE 3.43Å; K334-M338 HydrophobicContact CB-CE 4.37Å; K334-M338 PolarHBondContact O-N 2.55Å; K334-M338 VanDerWaalsContact O-N 3.15Å; Q335-M338 HydrophobicContact CG-SD 4.48Å; Q335-M338 WeakPolarHBondContact O-CB 3.26Å; Q335-M338 PolarHBondContact O-N 3.49Å; Q335-M338 VanDerWaalsContact O-N 3.12Å; M338-V341 PolarHBondContact O-N 3.48Å; M338-G342 PolarHBondContact O-N 2.95Å; M338-A379 HydrophobicContact CB-CB 4.15Å
339	A	98.1	Very high	96.4	Very high	0 Å²	0	41 Å²	41	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-65.9	-41.4	174.2	0	0	0	0	0	112.7	Q335 L337 V341 G342 L343 V376 A379 I380 M445	Q335-A339 PolarHBondContact O-N 2.97Å; L337-A339 VanDerWaalsContact C-N 3.32Å; L337-A339 PolarHBondContact O-N 3.32Å; A339-V341 VanDerWaalsContact C-N 3.33Å; A339-V341 PolarHBondContact O-N 3.5Å; A339-G342 PolarHBondContact O-N 3.11Å; A339-L343 PolarHBondContact O-N 3.1Å; A339-V376 HydrophobicContact CB-CG1 4.5Å; A339-V376 WeakPolarHBondContact O-CG2 3.41Å; A339-A379 HydrophobicContact CB-CB 4.25Å; A339-I380 HydrophobicContact CB-CD1 3.63Å; A339-I380 HydrophobicContact CB-CG1 3.76Å; A339-M445 HydrophobicContact CB-CE 3.8Å
340	A	98.3	Very high	96.5	Very high	8 Å²	8	36.9 Å²	36.9	7%	0.066	20%	0.2	C	C	.	.	H	α-helix	trans	-61.1	-41	175.6	0	0	0	0	0	112.5	W336 L337 A344 V442 M445	W336-A340 WeakPolarHBondContact O-CB 3.46Å; W336-A340 PolarHBondContact O-N 3.02Å; L337-A340 PolarHBondContact O-N 2.9Å; A340-A344 WeakPolarHBondContact O-CB 3.33Å; A340-A344 PolarHBondContact O-N 2.82Å; A340-V442 HydrophobicContact CB-CG1 4.27Å; A340-M445 HydrophobicContact CB-CB 3.81Å; A340-M445 HydrophobicContact CB-CG 4.19Å
341	V	98.4	Very high	96.6	Very high	67 Å²	67	34.8 Å²	34.8	41%	0.406	19%	0.191	S	C	.	.	H	α-helix	trans	-66.9	-41.6	174.1	170.8	0	0	0	0	110.7	L337 M338 A339 A344 I345 L375	L337-V341 HydrophobicContact CD1-CG2 4.41Å; L337-V341 HydrophobicContact CG-CG2 4.5Å; L337-V341 WeakPolarHBondContact O-CB 3.49Å; L337-V341 VanDerWaalsContact O-CG2 3.29Å; L337-V341 WeakPolarHBondContact O-CG2 3.44Å; L337-V341 PolarHBondContact O-N 3.11Å; M338-V341 PolarHBondContact O-N 3.48Å; A339-V341 VanDerWaalsContact C-N 3.33Å; A339-V341 PolarHBondContact O-N 3.5Å; V341-A344 PolarHBondContact O-N 3.48Å; V341-I345 HydrophobicContact CG1-CD1 3.77Å; V341-I345 HydrophobicContact CG1-CG1 4.35Å; V341-I345 VanDerWaalsContact O-CG1 3.29Å; V341-I345 WeakPolarHBondContact O-CG1 3.33Å; V341-I345 PolarHBondContact O-N 2.89Å; V341-L375 HydrophobicContact CG1-CD2 4.47Å
342	G	98.4	Very high	96.7	Very high	0 Å²	0	33.9 Å²	33.9	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-56	-50.7	174.2	0	0	0	0	0	112.5	M338 A339 A344 I345 E346 G372	M338-G342 PolarHBondContact O-N 2.95Å; A339-G342 PolarHBondContact O-N 3.11Å; G342-A344 VanDerWaalsContact C-N 3.33Å; G342-A344 PolarHBondContact O-N 3.44Å; G342-I345 PolarHBondContact O-N 3.07Å; G342-E346 WeakPolarHBondContact O-CB 3.3Å; G342-E346 PolarHBondContact O-N 3.38Å; G342-G372 WeakPolarHBondContact O-CA 3.35Å
343	L	98.3	Very high	97	Very high	0 Å²	0	31 Å²	31	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-59.8	-39.8	175.2	-77	177.2	0	0	0	112.9	V279 A280 A339 E346 G347 V376 Y441 V442 M445	V279-L343 HydrophobicContact CG1-CD2 4.01Å; A280-L343 HydrophobicContact CB-CD2 3.97Å; A339-L343 PolarHBondContact O-N 3.1Å; L343-E346 PolarHBondContact O-N 3.42Å; L343-G347 PolarHBondContact O-N 2.97Å; L343-V376 HydrophobicContact CD2-CG2 4.14Å; L343-V376 HydrophobicContact CG-CG2 3.87Å; L343-Y441 HydrophobicContact CD1-CD1 3.92Å; L343-V442 HydrophobicContact CB-CG2 3.75Å; L343-M445 HydrophobicContact CD1-CG 3.92Å; L343-M445 HydrophobicContact CD1-SD 4.36Å
344	A	98.4	Very high	97.2	Very high	40 Å²	40	29.1 Å²	29.1	33%	0.331	16%	0.161	S	C	.	.	H	α-helix	trans	-65.7	-41.3	177.7	0	0	0	0	0	112.1	A340 V341 G342 G348 L439 V442	A340-A344 WeakPolarHBondContact O-CB 3.33Å; A340-A344 PolarHBondContact O-N 2.82Å; V341-A344 PolarHBondContact O-N 3.48Å; G342-A344 VanDerWaalsContact C-N 3.33Å; G342-A344 PolarHBondContact O-N 3.44Å; A344-G348 PolarHBondContact O-N 3.14Å; A344-L439 HydrophobicContact CB-CD2 4.39Å; A344-V442 HydrophobicContact CB-CG2 4.18Å
345	I	98.3	Very high	97.1	Very high	51 Å²	51	30.4 Å²	30.4	26%	0.262	17%	0.167	S	C	.	.	H	α-helix	trans	-64.5	-44.5	175.4	-70.8	171	0	0	0	110.6	V341 G342 G348 S349 I368 Y371 L375	V341-I345 HydrophobicContact CG1-CD1 3.77Å; V341-I345 HydrophobicContact CG1-CG1 4.35Å; V341-I345 VanDerWaalsContact O-CG1 3.29Å; V341-I345 WeakPolarHBondContact O-CG1 3.33Å; V341-I345 PolarHBondContact O-N 2.89Å; G342-I345 PolarHBondContact O-N 3.07Å; I345-G348 PolarHBondContact O-N 2.89Å; I345-S349 PolarHBondContact O-N 3.16Å; I345-I368 HydrophobicContact CG2-CG2 3.35Å; I345-Y371 HydrophobicContact CD1-CD1 4.36Å; I345-Y371 HydrophobicContact CD1-CE1 4.17Å; I345-Y371 HydrophobicContact CG2-CD1 4.47Å; I345-L375 HydrophobicContact CD1-CD2 4.33Å
346	E	97.9	Very high	97.1	Very high	0 Å²	0	31.4 Å²	31.4	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-61.5	-47.9	177.7	-171.6	-162.6	141.6	0	0	111.8	A280 S283 G342 L343 G348 S349 C350 L369 I373 T438	A280-E346 WeakPolarHBondContact CA-OE2 3.2Å; A280-E346 WeakPolarHBondContact CB-OE2 3.38Å; S283-E346 WeakPolarHBondContact CB-OE1 3.48Å; S283-E346 PolarHBondContact OG-OE1 3.43Å; G342-E346 WeakPolarHBondContact O-CB 3.3Å; G342-E346 PolarHBondContact O-N 3.38Å; L343-E346 PolarHBondContact O-N 3.42Å; E346-G348 PolarHBondContact O-N 3.27Å; E346-S349 WeakPolarHBondContact O-CA 3.36Å; E346-S349 WeakPolarHBondContact O-CB 3.46Å; E346-S349 PolarHBondContact O-N 3.09Å; E346-S349 VanDerWaalsContact O-N 3.11Å; E346-C350 PolarHBondContact O-N 2.71Å; E346-C350 PolarHBondContact O-SG 3.32Å; E346-L369 HydrophobicContact CG-CG 4.18Å; E346-I373 HydrophobicContact CG-CG1 4.35Å; E346-T438 VanDerWaalsContact OE1-CG2 3.31Å; E346-T438 WeakPolarHBondContact OE1-CG2 3.31Å
347	G	97.8	Very high	96.8	Very high	0 Å²	0	35.7 Å²	35.7	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-63.1	-42.1	176.5	0	0	0	0	0	112.6	L343 S349 C350 F351 T435 T438	L343-G347 PolarHBondContact O-N 2.97Å; G347-S349 VanDerWaalsContact C-N 3.26Å; G347-S349 PolarHBondContact O-N 3.32Å; G347-C350 PolarHBondContact O-N 3.45Å; G347-F351 PolarHBondContact O-N 3.06Å; G347-F351 VanDerWaalsContact O-N 3.15Å; G347-T435 WeakPolarHBondContact O-CG2 3.46Å; G347-T435 PolarHBondContact O-OG1 3.06Å; G347-T438 WeakPolarHBondContact CA-OG1 3.42Å
348	G	97.6	Very high	96.5	Very high	33 Å²	33	35.5 Å²	35.5	34%	0.34	20%	0.202	S	C	.	.	H	α-helix	trans	-59.5	-37.3	172.1	0	0	0	0	0	112.5	A344 I345 E346 L352	A344-G348 PolarHBondContact O-N 3.14Å; I345-G348 PolarHBondContact O-N 2.89Å; E346-G348 PolarHBondContact O-N 3.27Å; G348-L352 WeakPolarHBondContact O-CG 3.28Å; G348-L352 PolarHBondContact O-N 2.98Å
349	S	97.7	Very high	96.1	Very high	1 Å²	1	36.3 Å²	36.3	1%	0.007	21%	0.205	C	C	.	.	H	α-helix	trans	-67.6	-47.5	174.8	-179	0	0	0	0	112.7	I345 E346 G347 F351 L352 I353 P365	I345-S349 PolarHBondContact O-N 3.16Å; E346-S349 WeakPolarHBondContact O-CA 3.36Å; E346-S349 WeakPolarHBondContact O-CB 3.46Å; E346-S349 PolarHBondContact O-N 3.09Å; E346-S349 VanDerWaalsContact O-N 3.11Å; G347-S349 VanDerWaalsContact C-N 3.26Å; G347-S349 PolarHBondContact O-N 3.32Å; S349-F351 PolarHBondContact O-N 3.14Å; S349-F351 VanDerWaalsContact O-N 3.16Å; S349-L352 PolarHBondContact O-N 3.41Å; S349-I353 WeakPolarHBondContact O-CG1 3.46Å; S349-I353 PolarHBondContact O-N 3.21Å; S349-I353 VanDerWaalsContact O-N 3.1Å; S349-P365 WeakPolarHBondContact OG-CA 3.33Å; S349-P365 WeakPolarHBondContact OG-CB 3.4Å; S349-P365 PolarHBondContact OG-O 3.11Å
350	C	97	Very high	95.7	Very high	2 Å²	2	41.9 Å²	41.9	1%	0.014	23%	0.234	C	C	.	.	H	α-helix	trans	-52.8	-39.6	177.1	-67.8	0	0	0	0	111.5	E346 G347 L352 P354 N431 M434 T435	E346-C350 PolarHBondContact O-N 2.71Å; E346-C350 PolarHBondContact O-SG 3.32Å; G347-C350 PolarHBondContact O-N 3.45Å; C350-L352 VanDerWaalsContact C-N 3.35Å; C350-L352 PolarHBondContact O-N 3.11Å; C350-P354 VanDerWaalsContact O-CD 3.25Å; C350-P354 WeakPolarHBondContact O-CD 3.47Å; C350-N431 WeakPolarHBondContact O-CB 3.29Å; C350-N431 PolarHBondContact O-OD1 3.19Å; C350-M434 HydrophobicContact CB-CB 4.43Å; C350-T435 WeakPolarHBondContact CB-OG1 3.43Å
351	F	96.9	Very high	95.6	Very high	100 Å²	100	42.8 Å²	42.8	44%	0.439	24%	0.241	S	C	.	.	H	α-helix	trans	-63.9	-37.1	176	-176.7	-101	0	0	0	113.1	G347 S349 P354 F355 T435	G347-F351 PolarHBondContact O-N 3.06Å; G347-F351 VanDerWaalsContact O-N 3.15Å; S349-F351 PolarHBondContact O-N 3.14Å; S349-F351 VanDerWaalsContact O-N 3.16Å; F351-P354 WeakPolarHBondContact O-CD 3.22Å; F351-P354 WeakPolarHBondContact O-CG 3.32Å; F351-F355 HydrophobicContact CD1-CE2 4.25Å; F351-F355 HydrophobicContact CD2-CE2 4.44Å; F351-F355 AromaticContact CE1-CE2 3.9Å; F351-F355 HydrophobicContact CE1-CE2 3.9Å; F351-F355 HydrophobicContact CE2-CE2 4.1Å; F351-F355 AromaticContact CZ-CE2 3.82Å; F351-F355 HydrophobicContact CZ-CE2 3.82Å; F351-F355 HydrophobicContact CZ-CZ 4.27Å; F351-F355 WeakPolarHBondContact O-CD2 3.39Å; F351-F355 WeakPolarHBondContact O-CE2 3.08Å; F351-T435 WeakPolarHBondContact CA-OG1 3.29Å; F351-T435 HydrophobicContact CB-CG2 4.01Å; F351-T435 PolarHBondContact N-OG1 3.32Å; F351-T435 VanDerWaalsContact N-OG1 3.09Å
352	L	96.6	Very high	95.4	Very high	89 Å²	89	39.6 Å²	39.6	47%	0.466	22%	0.222	S	C	.	.	H	α-helix	trans	-77.9	-34.2	-175.8	-68.9	172	0	0	0	113.7	G348 S349 C350 F355 P365	G348-L352 WeakPolarHBondContact O-CG 3.28Å; G348-L352 PolarHBondContact O-N 2.98Å; S349-L352 PolarHBondContact O-N 3.41Å; C350-L352 VanDerWaalsContact C-N 3.35Å; C350-L352 PolarHBondContact O-N 3.11Å; L352-F355 PolarHBondContact O-N 2.99Å; L352-F355 VanDerWaalsContact O-N 3.07Å; L352-P365 HydrophobicContact CB-CB 4.15Å
353	I	96.3	Very high	95.3	Very high	0 Å²	0	41.9 Å²	41.9	0%	0	23%	0.233	C	C	.	.	G	3₁₀ helix	trans	-45	-54.1	-178.6	-70.7	173.9	0	0	0	114	L287 W294 S349 F355 C356 L362 P365 L369 F427	L287-I353 HydrophobicContact CD1-CD1 4.12Å; L287-I353 HydrophobicContact CD1-CG2 4.07Å; L287-I353 HydrophobicContact CD2-CD1 3.64Å; W294-I353 WeakPolarHBondContact CH2-O 3.43Å; S349-I353 WeakPolarHBondContact O-CG1 3.46Å; S349-I353 PolarHBondContact O-N 3.21Å; S349-I353 VanDerWaalsContact O-N 3.1Å; I353-F355 PolarHBondContact O-N 2.99Å; I353-F355 VanDerWaalsContact O-N 3.1Å; I353-C356 PolarHBondContact O-N 3.24Å; I353-L362 HydrophobicContact CG2-CD1 4Å; I353-P365 HydrophobicContact CG1-CB 3.8Å; I353-P365 HydrophobicContact CG1-CG 4.06Å; I353-L369 HydrophobicContact CD1-CD1 3.94Å; I353-F427 HydrophobicContact CG2-CE1 3.83Å; I353-F427 HydrophobicContact CG2-CZ 3.83Å
354	P	94.2	Very high	95.2	Very high	12 Å²	12	47 Å²	47	8%	0.078	26%	0.259	C	S	.	.	G	3₁₀ helix	trans	-66.5	-14.2	-175.1	25.3	-36	0	0	0	114.5	C350 F351 F427 I428 N431	C350-P354 VanDerWaalsContact O-CD 3.25Å; C350-P354 WeakPolarHBondContact O-CD 3.47Å; F351-P354 WeakPolarHBondContact O-CD 3.22Å; F351-P354 WeakPolarHBondContact O-CG 3.32Å; P354-F427 HydrophobicContact CB-CD1 4.24Å; P354-F427 HydrophobicContact CB-CE1 4.4Å; P354-I428 HydrophobicContact CB-CB 4.42Å; P354-I428 HydrophobicContact CB-CG1 4.02Å; P354-N431 HydrophobicContact CB-CB 4.47Å; P354-N431 HydrophobicContact CG-CB 3.84Å
355	F	94	Very high	95.1	Very high	117 Å²	117	45.3 Å²	45.3	51%	0.513	25%	0.245	S	C	.	.	G	3₁₀ helix	trans	-94.9	-3.5	-179.2	-58	-68.7	0	0	0	113.4	F351 L352 I353	F351-F355 HydrophobicContact CD1-CE2 4.25Å; F351-F355 HydrophobicContact CD2-CE2 4.44Å; F351-F355 AromaticContact CE1-CE2 3.9Å; F351-F355 HydrophobicContact CE1-CE2 3.9Å; F351-F355 HydrophobicContact CE2-CE2 4.1Å; F351-F355 AromaticContact CZ-CE2 3.82Å; F351-F355 HydrophobicContact CZ-CE2 3.82Å; F351-F355 HydrophobicContact CZ-CZ 4.27Å; F351-F355 WeakPolarHBondContact O-CD2 3.39Å; F351-F355 WeakPolarHBondContact O-CE2 3.08Å; L352-F355 PolarHBondContact O-N 2.99Å; L352-F355 VanDerWaalsContact O-N 3.07Å; I353-F355 PolarHBondContact O-N 2.99Å; I353-F355 VanDerWaalsContact O-N 3.1Å
356	C	94.5	Very high	95	Very high	21 Å²	21	42.9 Å²	42.9	14%	0.142	23%	0.233	C	C	.	.			trans	-67.6	135.2	175.8	-66.2	0	0	0	0	111.1	W294 M299 I353 L362	W294-C356 HydrophobicContact CH2-CB 4.34Å; M299-C356 HydrophobicContact CE-CB 3.93Å; M299-C356 WeakPolarHBondContact CE-O 3.41Å; I353-C356 PolarHBondContact O-N 3.24Å; C356-L362 HydrophobicContact CB-CB 4.07Å; C356-L362 HydrophobicContact CB-CD1 4.12Å
357	T	89.2	Confident	94.9	Very high	116 Å²	116	43.8 Å²	43.8	71%	0.712	24%	0.239	S	C	*	.			trans	-101.3	-18.4	-177	55.2	0	0	0	0	113.9
358	N	90.8	Very high	94.9	Very high	73 Å²	73	46.8 Å²	46.8	39%	0.39	25%	0.254	S	S	.	.	S	Bend	trans	-141.6	159.9	179.8	67.3	77.5	0	0	0	111.9	I360 A361 L362	N358-I360 VanDerWaalsContact C-N 3.33Å; N358-I360 PolarHBondContact O-N 3.3Å; N358-I360 PolarHBondContact OD1-N 3.48Å; N358-A361 PolarHBondContact O-N 3.42Å; N358-A361 WeakPolarHBondContact OD1-CB 3.5Å; N358-A361 PolarHBondContact OD1-N 2.91Å; N358-L362 PolarHBondContact O-N 3.32Å; N358-L362 VanDerWaalsContact O-N 3.08Å
359	F	88.6	Confident	94.9	Very high	33 Å²	33	45.2 Å²	45.2	15%	0.145	24%	0.238	C	C	.	.	H	α-helix	trans	-54.4	-43	-177.9	163.9	-108.6	0	0	0	113.5	M295 Q305 L308 V309 L362 M363	M295-F359 HydrophobicContact CE-CD2 3.63Å; M295-F359 HydrophobicContact CE-CE2 4.25Å; Q305-F359 HydrophobicContact CB-CD1 4.48Å; Q305-F359 HydrophobicContact CB-CD2 3.89Å; Q305-F359 HydrophobicContact CB-CE2 4.06Å; Q305-F359 HydrophobicContact CB-CG 4.11Å; Q305-F359 HydrophobicContact CB-CZ 4.43Å; Q305-F359 HydrophobicContact CG-CD1 4.18Å; Q305-F359 HydrophobicContact CG-CD2 4.46Å; Q305-F359 HydrophobicContact CG-CE1 4.37Å; Q305-F359 HydrophobicContact CG-CG 4.22Å; Q305-F359 WeakPolarHBondContact O-CE2 3.46Å; L308-F359 HydrophobicContact CB-CE2 4.38Å; L308-F359 HydrophobicContact CB-CZ 3.74Å; V309-F359 VanDerWaalsContact CA-CE2 3.49Å; V309-F359 HydrophobicContact CB-CD2 4.15Å; V309-F359 HydrophobicContact CB-CE2 3.57Å; V309-F359 HydrophobicContact CG2-CD2 3.99Å; V309-F359 HydrophobicContact CG2-CE2 3.79Å; F359-L362 WeakPolarHBondContact O-CB 3.38Å; F359-L362 PolarHBondContact O-N 3.02Å; F359-M363 HydrophobicContact CD1-SD 4.34Å; F359-M363 HydrophobicContact CE1-SD 3.79Å; F359-M363 HydrophobicContact CE2-CG 4.48Å; F359-M363 HydrophobicContact CE2-SD 4.35Å; F359-M363 HydrophobicContact CZ-CG 4.44Å; F359-M363 HydrophobicContact CZ-SD 3.8Å; F359-M363 PolarHBondContact O-N 2.9Å
360	I	91.7	Very high	94.9	Very high	116 Å²	116	45.8 Å²	45.8	60%	0.595	24%	0.242	S	C	*	.	H	α-helix	trans	-70.1	-40.6	-178.7	-60.6	176.9	0	0	0	110.8	N358 L362 M363	N358-I360 VanDerWaalsContact C-N 3.33Å; N358-I360 PolarHBondContact O-N 3.3Å; N358-I360 PolarHBondContact OD1-N 3.48Å; I360-L362 PolarHBondContact O-N 3.42Å; I360-M363 HydrophobicContact CB-SD 4.47Å; I360-M363 HydrophobicContact CG1-SD 4.47Å; I360-M363 WeakPolarHBondContact O-CB 3.36Å; I360-M363 PolarHBondContact O-N 3.26Å
361	A	94.4	Very high	94.9	Very high	28 Å²	28	48.6 Å²	48.6	23%	0.231	25%	0.253	C	S	.	.	H	α-helix	trans	-63.6	-30.9	176.4	0	0	0	0	0	112	N358 I364 P365	N358-A361 PolarHBondContact O-N 3.42Å; N358-A361 WeakPolarHBondContact OD1-CB 3.5Å; N358-A361 PolarHBondContact OD1-N 2.91Å; A361-I364 PolarHBondContact O-N 2.88Å; A361-P365 WeakPolarHBondContact O-CD 3.47Å
362	L	95.4	Very high	95	Very high	0 Å²	0	43.8 Å²	43.8	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-71.6	-28.6	177.2	-177.5	61.7	0	0	0	113.3	I291 W294 M295 M299 V309 I353 C356 N358 F359 I360 I364 P365 I366	I291-L362 HydrophobicContact CD1-CD1 4.39Å; I291-L362 HydrophobicContact CD1-CD2 4Å; I291-L362 HydrophobicContact CD1-CG 4.38Å; I291-L362 HydrophobicContact CG1-CD2 4.28Å; W294-L362 HydrophobicContact CE3-CD2 4.45Å; W294-L362 HydrophobicContact CH2-CD1 4.46Å; W294-L362 HydrophobicContact CZ3-CD1 3.88Å; W294-L362 HydrophobicContact CZ3-CD2 3.8Å; W294-L362 HydrophobicContact CZ3-CG 4.45Å; M295-L362 HydrophobicContact CE-CD2 4.28Å; M295-L362 HydrophobicContact CG-CD2 3.58Å; M295-L362 HydrophobicContact SD-CD2 3.56Å; M295-L362 VanDerWaalsContact SD-CD2 3.56Å; M299-L362 HydrophobicContact CE-CB 4.37Å; M299-L362 HydrophobicContact CE-CD2 4.4Å; M299-L362 HydrophobicContact SD-CD2 4.48Å; V309-L362 HydrophobicContact CG2-CB 4.34Å; V309-L362 HydrophobicContact CG2-CD2 3.89Å; V309-L362 HydrophobicContact CG2-CG 3.96Å; I353-L362 HydrophobicContact CG2-CD1 4Å; C356-L362 HydrophobicContact CB-CB 4.07Å; C356-L362 HydrophobicContact CB-CD1 4.12Å; N358-L362 PolarHBondContact O-N 3.32Å; N358-L362 VanDerWaalsContact O-N 3.08Å; F359-L362 WeakPolarHBondContact O-CB 3.38Å; F359-L362 PolarHBondContact O-N 3.02Å; I360-L362 PolarHBondContact O-N 3.42Å; L362-I364 PolarHBondContact O-N 3.34Å; L362-P365 HydrophobicContact CD1-CG 4.48Å; L362-P365 VanDerWaalsContact O-CD 3.24Å; L362-P365 WeakPolarHBondContact O-CD 3.23Å; L362-P365 WeakPolarHBondContact O-CG 3.47Å; L362-I366 HydrophobicContact CD1-CD1 4.28Å; L362-I366 HydrophobicContact CD1-CG1 4.44Å; L362-I366 HydrophobicContact CG-CD1 3.9Å; L362-I366 HydrophobicContact CG-CG1 4.49Å; L362-I366 WeakPolarHBondContact O-CG1 3.4Å; L362-I366 PolarHBondContact O-N 3.02Å
363	M	95	Very high	95.1	Very high	48 Å²	48	39.8 Å²	39.8	24%	0.236	21%	0.211	C	C	.	.	H	α-helix	trans	-61.1	-28.9	175.6	-67	155.8	77.4	0	0	112.1	V309 P312 F359 I360 S367	V309-M363 HydrophobicContact CG2-CG 4.05Å; P312-M363 HydrophobicContact CB-CE 4.23Å; P312-M363 HydrophobicContact CG-CB 4.09Å; P312-M363 HydrophobicContact CG-CE 3.05Å; P312-M363 HydrophobicContact CG-CG 3.97Å; P312-M363 HydrophobicContact CG-SD 4.28Å; F359-M363 HydrophobicContact CD1-SD 4.34Å; F359-M363 HydrophobicContact CE1-SD 3.79Å; F359-M363 HydrophobicContact CE2-CG 4.48Å; F359-M363 HydrophobicContact CE2-SD 4.35Å; F359-M363 HydrophobicContact CZ-CG 4.44Å; F359-M363 HydrophobicContact CZ-SD 3.8Å; F359-M363 PolarHBondContact O-N 2.9Å; I360-M363 HydrophobicContact CB-SD 4.47Å; I360-M363 HydrophobicContact CG1-SD 4.47Å; I360-M363 WeakPolarHBondContact O-CB 3.36Å; I360-M363 PolarHBondContact O-N 3.26Å; M363-S367 WeakPolarHBondContact O-CB 3.36Å; M363-S367 PolarHBondContact O-N 2.92Å; M363-S367 PolarHBondContact O-OG 3.31Å
364	I	96	Very high	95.2	Very high	106 Å²	106	39.8 Å²	39.8	54%	0.544	21%	0.211	S	C	.	.	H	α-helix	trans	-68.1	-57.9	-178.3	-62.1	170.9	0	0	0	112.4	A361 L362 I366 S367 I368	A361-I364 PolarHBondContact O-N 2.88Å; L362-I364 PolarHBondContact O-N 3.34Å; I364-I366 PolarHBondContact O-N 3.45Å; I364-S367 VanDerWaalsContact O-CB 3.27Å; I364-S367 WeakPolarHBondContact O-CB 3.05Å; I364-S367 PolarHBondContact O-N 3.47Å; I364-I368 HydrophobicContact CG2-CD1 4Å; I364-I368 WeakPolarHBondContact O-CG1 3.26Å; I364-I368 PolarHBondContact O-N 3.34Å
365	P	97.2	Very high	95.4	Very high	5 Å²	5	39.5 Å²	39.5	3%	0.032	21%	0.209	C	C	.	.	H	α-helix	trans	-63.4	-39.9	177.9	24.6	-33.7	0	0	0	111.9	S349 L352 I353 A361 L362 S367 I368 L369	S349-P365 WeakPolarHBondContact OG-CA 3.33Å; S349-P365 WeakPolarHBondContact OG-CB 3.4Å; S349-P365 PolarHBondContact OG-O 3.11Å; L352-P365 HydrophobicContact CB-CB 4.15Å; I353-P365 HydrophobicContact CG1-CB 3.8Å; I353-P365 HydrophobicContact CG1-CG 4.06Å; A361-P365 WeakPolarHBondContact O-CD 3.47Å; L362-P365 HydrophobicContact CD1-CG 4.48Å; L362-P365 VanDerWaalsContact O-CD 3.24Å; L362-P365 WeakPolarHBondContact O-CD 3.23Å; L362-P365 WeakPolarHBondContact O-CG 3.47Å; P365-S367 PolarHBondContact O-N 3.47Å; P365-I368 CarbonylContact O-C 3.55Å; P365-I368 WeakPolarHBondContact O-CA 3.24Å; P365-I368 WeakPolarHBondContact O-CB 3.44Å; P365-I368 PolarHBondContact O-N 2.96Å; P365-L369 WeakPolarHBondContact O-CB 3.17Å; P365-L369 PolarHBondContact O-N 2.76Å
366	I	95.9	Very high	95.6	Very high	0 Å²	0	34 Å²	34	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-58.3	-41.1	175.5	-61.5	173.7	0	0	0	111	L287 I291 V309 W310 A313 L362 I364 I368 L369 C370	L287-I366 HydrophobicContact CD2-CG1 4.4Å; I291-I366 HydrophobicContact CD1-CD1 3.44Å; I291-I366 VanDerWaalsContact CD1-CD1 3.44Å; I291-I366 HydrophobicContact CD1-CG1 4.27Å; V309-I366 HydrophobicContact CB-CD1 4.4Å; V309-I366 HydrophobicContact CG1-CD1 4Å; V309-I366 HydrophobicContact CG2-CD1 3.62Å; W310-I366 HydrophobicContact CE3-CG2 3.57Å; W310-I366 HydrophobicContact CZ3-CG2 3.55Å; A313-I366 HydrophobicContact CB-CG2 3.82Å; L362-I366 HydrophobicContact CD1-CD1 4.28Å; L362-I366 HydrophobicContact CD1-CG1 4.44Å; L362-I366 HydrophobicContact CG-CD1 3.9Å; L362-I366 HydrophobicContact CG-CG1 4.49Å; L362-I366 WeakPolarHBondContact O-CG1 3.4Å; L362-I366 PolarHBondContact O-N 3.02Å; I364-I366 PolarHBondContact O-N 3.45Å; I366-I368 VanDerWaalsContact C-N 3.35Å; I366-I368 PolarHBondContact O-N 3.07Å; I366-L369 WeakPolarHBondContact O-CB 3.18Å; I366-L369 PolarHBondContact O-N 3.44Å; I366-C370 PolarHBondContact O-N 2.95Å
367	S	96.6	Very high	95.7	Very high	19 Å²	19	33.3 Å²	33.3	13%	0.133	18%	0.179	C	C	.	.	H	α-helix	trans	-59.1	-43.6	173.2	-71.4	0	0	0	0	112.7	P316 M363 I364 P365 L369 Y371	P316-S367 WeakPolarHBondContact CB-O 3.31Å; M363-S367 WeakPolarHBondContact O-CB 3.36Å; M363-S367 PolarHBondContact O-N 2.92Å; M363-S367 PolarHBondContact O-OG 3.31Å; I364-S367 VanDerWaalsContact O-CB 3.27Å; I364-S367 WeakPolarHBondContact O-CB 3.05Å; I364-S367 PolarHBondContact O-N 3.47Å; P365-S367 PolarHBondContact O-N 3.47Å; S367-L369 VanDerWaalsContact C-N 3.35Å; S367-Y371 WeakPolarHBondContact O-CB 3.44Å; S367-Y371 PolarHBondContact O-N 3.18Å
368	I	98	Very high	96.1	Very high	63 Å²	63	27.8 Å²	27.8	32%	0.323	15%	0.145	S	C	.	.	H	α-helix	trans	-66.1	-38.5	176.7	-65	168.6	0	0	0	111.1	I345 I364 P365 I366 Y371 G372	I345-I368 HydrophobicContact CG2-CG2 3.35Å; I364-I368 HydrophobicContact CG2-CD1 4Å; I364-I368 WeakPolarHBondContact O-CG1 3.26Å; I364-I368 PolarHBondContact O-N 3.34Å; P365-I368 CarbonylContact O-C 3.55Å; P365-I368 WeakPolarHBondContact O-CA 3.24Å; P365-I368 WeakPolarHBondContact O-CB 3.44Å; P365-I368 PolarHBondContact O-N 2.96Å; I366-I368 VanDerWaalsContact C-N 3.35Å; I366-I368 PolarHBondContact O-N 3.07Å; I368-Y371 PolarHBondContact O-N 3.06Å; I368-G372 PolarHBondContact O-N 2.93Å
369	L	97.7	Very high	96.5	Very high	1 Å²	1	24.3 Å²	24.3	1%	0.005	13%	0.127	C	C	.	.	H	α-helix	trans	-61.3	-52.3	177.2	-179.3	148.2	0	0	0	110.4	L284 L287 E346 I353 P365 I366 S367 Y371 G372 I373	L284-L369 HydrophobicContact CB-CD2 4.25Å; L284-L369 HydrophobicContact CD1-CD2 4.06Å; L287-L369 HydrophobicContact CD2-CD1 4.12Å; E346-L369 HydrophobicContact CG-CG 4.18Å; I353-L369 HydrophobicContact CD1-CD1 3.94Å; P365-L369 WeakPolarHBondContact O-CB 3.17Å; P365-L369 PolarHBondContact O-N 2.76Å; I366-L369 WeakPolarHBondContact O-CB 3.18Å; I366-L369 PolarHBondContact O-N 3.44Å; S367-L369 VanDerWaalsContact C-N 3.35Å; L369-Y371 VanDerWaalsContact C-N 3.31Å; L369-Y371 PolarHBondContact O-N 3.38Å; L369-G372 WeakPolarHBondContact O-CA 3.49Å; L369-G372 PolarHBondContact O-N 3.23Å; L369-I373 HydrophobicContact CD2-CD1 3.54Å; L369-I373 HydrophobicContact CD2-CG1 4.42Å; L369-I373 HydrophobicContact CG-CD1 4.4Å; L369-I373 WeakPolarHBondContact O-CG1 3.26Å; L369-I373 PolarHBondContact O-N 3.28Å
370	C	97	Very high	96.9	Very high	13 Å²	13	22.7 Å²	22.7	9%	0.088	12%	0.12	C	C	.	.	H	α-helix	trans	-67.7	-29.8	179.8	-64.4	0	0	0	0	113.1	A313 H317 I366 A374	A313-C370 HydrophobicContact CB-CB 4.05Å; H317-C370 HydrophobicContact CB-CB 4.18Å; H317-C370 PolarHBondContact CD2-O 2.85Å; I366-C370 PolarHBondContact O-N 2.95Å; C370-A374 WeakPolarHBondContact O-CB 3.36Å; C370-A374 PolarHBondContact O-N 3.39Å; C370-A374 VanDerWaalsContact O-N 3.08Å
371	Y	98	Very high	97.2	Very high	60 Å²	60	17.2 Å²	17.2	24%	0.235	9%	0.092	C	C	.	.	H	α-helix	trans	-61.7	-46.4	168.6	-178.9	-91	0	0	0	111.1	P316 A319 G320 T323 I345 S367 I368 L369 A374 L375	P316-Y371 VanDerWaalsContact O-CD2 3.26Å; P316-Y371 WeakPolarHBondContact O-CD2 3.48Å; A319-Y371 HydrophobicContact CB-CE2 4.44Å; G320-Y371 VanDerWaalsContact CA-CE2 3.41Å; T323-Y371 WeakPolarHBondContact CG2-OH 3.41Å; T323-Y371 PolarHBondContact OG1-OH 3.36Å; I345-Y371 HydrophobicContact CD1-CD1 4.36Å; I345-Y371 HydrophobicContact CD1-CE1 4.17Å; I345-Y371 HydrophobicContact CG2-CD1 4.47Å; S367-Y371 WeakPolarHBondContact O-CB 3.44Å; S367-Y371 PolarHBondContact O-N 3.18Å; I368-Y371 PolarHBondContact O-N 3.06Å; L369-Y371 VanDerWaalsContact C-N 3.31Å; L369-Y371 PolarHBondContact O-N 3.38Å; Y371-A374 WeakPolarHBondContact O-CB 3.3Å; Y371-A374 PolarHBondContact O-N 3.28Å; Y371-L375 HydrophobicContact CD1-CD1 3.79Å; Y371-L375 HydrophobicContact CD1-CD2 4.41Å; Y371-L375 HydrophobicContact CD2-CD1 4.37Å; Y371-L375 HydrophobicContact CE1-CD1 3.42Å; Y371-L375 VanDerWaalsContact CE1-CD1 3.42Å; Y371-L375 HydrophobicContact CE1-CD2 3.78Å; Y371-L375 HydrophobicContact CE1-CG 4.28Å; Y371-L375 HydrophobicContact CE2-CD1 4.04Å; Y371-L375 HydrophobicContact CG-CD1 4.25Å; Y371-L375 WeakPolarHBondContact O-CD1 3.2Å; Y371-L375 PolarHBondContact O-N 3.36Å; Y371-L375 VanDerWaalsContact O-N 3.11Å
372	G	98.3	Very high	97.3	Very high	0 Å²	0	15.9 Å²	15.9	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-59.2	-46.8	176.9	0	0	0	0	0	113	G342 I368 L369 A374 L375 V376	G342-G372 WeakPolarHBondContact O-CA 3.35Å; I368-G372 PolarHBondContact O-N 2.93Å; L369-G372 WeakPolarHBondContact O-CA 3.49Å; L369-G372 PolarHBondContact O-N 3.23Å; G372-A374 VanDerWaalsContact C-N 3.35Å; G372-A374 PolarHBondContact O-N 2.93Å; G372-L375 WeakPolarHBondContact O-CB 3.33Å; G372-L375 PolarHBondContact O-N 3.1Å; G372-L375 VanDerWaalsContact O-N 3.16Å; G372-V376 PolarHBondContact O-N 3.49Å; G372-V376 VanDerWaalsContact O-N 3.14Å
373	I	97.9	Very high	97.4	Very high	4 Å²	4	15.9 Å²	15.9	2%	0.021	8%	0.081	C	C	.	.	H	α-helix	trans	-58.3	-46.7	176.1	-66.4	175.8	0	0	0	110.9	A280 L284 E346 L369 L375 V376 D377	A280-I373 WeakPolarHBondContact O-CD1 3.45Å; A280-I373 WeakPolarHBondContact O-CG1 3.25Å; L284-I373 HydrophobicContact CB-CD1 3.73Å; L284-I373 HydrophobicContact CD2-CD1 4.06Å; L284-I373 HydrophobicContact CG-CD1 4.46Å; E346-I373 HydrophobicContact CG-CG1 4.35Å; L369-I373 HydrophobicContact CD2-CD1 3.54Å; L369-I373 HydrophobicContact CD2-CG1 4.42Å; L369-I373 HydrophobicContact CG-CD1 4.4Å; L369-I373 WeakPolarHBondContact O-CG1 3.26Å; L369-I373 PolarHBondContact O-N 3.28Å; I373-L375 VanDerWaalsContact C-N 3.26Å; I373-L375 PolarHBondContact O-N 3.41Å; I373-V376 PolarHBondContact O-N 2.92Å; I373-D377 WeakPolarHBondContact CG2-OD2 3.44Å; I373-D377 PolarHBondContact O-N 3.22Å
374	A	98.1	Very high	97.5	Very high	0 Å²	0	13.6 Å²	13.6	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-58.9	-37.5	178.1	0	0	0	0	0	112.9	H317 V321 C370 Y371 G372 T378	H317-A374 HydrophobicContact CB-CB 4.49Å; H317-A374 WeakPolarHBondContact O-CB 3.32Å; V321-A374 HydrophobicContact CG2-CB 4.12Å; C370-A374 WeakPolarHBondContact O-CB 3.36Å; C370-A374 PolarHBondContact O-N 3.39Å; C370-A374 VanDerWaalsContact O-N 3.08Å; Y371-A374 WeakPolarHBondContact O-CB 3.3Å; Y371-A374 PolarHBondContact O-N 3.28Å; G372-A374 VanDerWaalsContact C-N 3.35Å; G372-A374 PolarHBondContact O-N 2.93Å; A374-T378 WeakPolarHBondContact O-CB 3.47Å; A374-T378 PolarHBondContact O-N 3.44Å; A374-T378 VanDerWaalsContact O-N 3.09Å; A374-T378 PolarHBondContact O-OG1 2.98Å
375	L	98.3	Very high	97.5	Very high	7 Å²	7	8.5 Å²	8.5	4%	0.037	4%	0.043	C	C	.	.	H	α-helix	trans	-63.4	-42.3	175.4	-96.1	64.6	0	0	0	111.8	G320 T324 V341 I345 Y371 G372 I373 A379	G320-L375 VanDerWaalsContact CA-CD1 3.46Å; T324-L375 WeakPolarHBondContact OG1-CA 3.34Å; V341-L375 HydrophobicContact CG1-CD2 4.47Å; I345-L375 HydrophobicContact CD1-CD2 4.33Å; Y371-L375 HydrophobicContact CD1-CD1 3.79Å; Y371-L375 HydrophobicContact CD1-CD2 4.41Å; Y371-L375 HydrophobicContact CD2-CD1 4.37Å; Y371-L375 HydrophobicContact CE1-CD1 3.42Å; Y371-L375 VanDerWaalsContact CE1-CD1 3.42Å; Y371-L375 HydrophobicContact CE1-CD2 3.78Å; Y371-L375 HydrophobicContact CE1-CG 4.28Å; Y371-L375 HydrophobicContact CE2-CD1 4.04Å; Y371-L375 HydrophobicContact CG-CD1 4.25Å; Y371-L375 WeakPolarHBondContact O-CD1 3.2Å; Y371-L375 PolarHBondContact O-N 3.36Å; Y371-L375 VanDerWaalsContact O-N 3.11Å; G372-L375 WeakPolarHBondContact O-CB 3.33Å; G372-L375 PolarHBondContact O-N 3.1Å; G372-L375 VanDerWaalsContact O-N 3.16Å; I373-L375 VanDerWaalsContact C-N 3.26Å; I373-L375 PolarHBondContact O-N 3.41Å; L375-A379 VanDerWaalsContact O-CB 3.22Å; L375-A379 WeakPolarHBondContact O-CB 3.44Å; L375-A379 PolarHBondContact O-N 3.02Å
376	V	98.5	Very high	97.4	Very high	0 Å²	0	8.9 Å²	8.9	0%	0	5%	0.045	C	C	.	.	H	α-helix	trans	-67.2	-56.7	178.1	177.7	0	0	0	0	110.5	C276 A280 A339 L343 G372 I373 T378 A379 I380	C276-V376 WeakPolarHBondContact SG-CG1 3.44Å; A280-V376 HydrophobicContact CB-CB 3.96Å; A280-V376 HydrophobicContact CB-CG1 3.73Å; A280-V376 HydrophobicContact CB-CG2 4.09Å; A339-V376 HydrophobicContact CB-CG1 4.5Å; A339-V376 WeakPolarHBondContact O-CG2 3.41Å; L343-V376 HydrophobicContact CD2-CG2 4.14Å; L343-V376 HydrophobicContact CG-CG2 3.87Å; G372-V376 PolarHBondContact O-N 3.49Å; G372-V376 VanDerWaalsContact O-N 3.14Å; I373-V376 PolarHBondContact O-N 2.92Å; V376-T378 PolarHBondContact O-N 3.31Å; V376-A379 PolarHBondContact O-N 2.89Å; V376-A379 VanDerWaalsContact O-N 3.16Å; V376-I380 HydrophobicContact CG1-CG1 4Å; V376-I380 WeakPolarHBondContact O-CB 3.19Å; V376-I380 VanDerWaalsContact O-CG1 3.28Å; V376-I380 WeakPolarHBondContact O-CG1 3.48Å; V376-I380 PolarHBondContact O-N 3.12Å
377	D	97.8	Very high	97.4	Very high	7 Å²	7	9 Å²	9	4%	0.037	5%	0.045	C	C	.	.	H	α-helix	trans	-61.9	-44.6	-173.1	-70.8	-24.1	0	0	0	111.9	L194 L277 N281 I373 A379 I380 L381 Y407	L194-D377 HydrophobicContact CD1-CB 3.65Å; L194-D377 HydrophobicContact CD2-CB 4.37Å; L277-D377 VanDerWaalsContact CD2-OD1 3.24Å; L277-D377 WeakPolarHBondContact CD2-OD1 3.47Å; N281-D377 PolarHBondContact ND2-OD1 2.79Å; I373-D377 WeakPolarHBondContact CG2-OD2 3.44Å; I373-D377 PolarHBondContact O-N 3.22Å; D377-A379 VanDerWaalsContact C-N 3.26Å; D377-A379 PolarHBondContact O-N 3.26Å; D377-I380 PolarHBondContact O-N 3.17Å; D377-L381 WeakPolarHBondContact O-CG 3.49Å; D377-L381 PolarHBondContact O-N 3.41Å; D377-L381 VanDerWaalsContact O-N 3.14Å; D377-Y407 VanDerWaalsContact CG-OH 3.3Å; D377-Y407 WeakPolarHBondContact OD1-CE1 3.37Å; D377-Y407 PolarHBondContact OD1-OH 3.14Å
378	T	98.1	Very high	97.4	Very high	0 Å²	0	8.1 Å²	8.1	0%	0	4%	0.039	C	C	.	.	H	α-helix	trans	-67	-27.8	-179.3	-51.6	0	0	0	0	112.3	V321 T324 I325 A374 V376 P382	V321-T378 HydrophobicContact CG1-CG2 4.37Å; T324-T378 HydrophobicContact CG2-CG2 3.76Å; I325-T378 HydrophobicContact CG1-CG2 4.06Å; A374-T378 WeakPolarHBondContact O-CB 3.47Å; A374-T378 PolarHBondContact O-N 3.44Å; A374-T378 VanDerWaalsContact O-N 3.09Å; A374-T378 PolarHBondContact O-OG1 2.98Å; V376-T378 PolarHBondContact O-N 3.31Å; T378-P382 WeakPolarHBondContact O-CD 3.43Å; T378-P382 VanDerWaalsContact O-CG 3.29Å; T378-P382 WeakPolarHBondContact O-CG 3.45Å
379	A	97.8	Very high	97.2	Very high	0 Å²	0	6 Å²	6	0%	0	3%	0.028	C	C	.	.	H	α-helix	trans	-88.1	-35.6	177.8	0	0	0	0	0	112.8	T324 Q335 M338 A339 L375 V376 D377 T383	T324-A379 HydrophobicContact CG2-CB 3.94Å; Q335-A379 HydrophobicContact CB-CB 4.26Å; Q335-A379 PolarHBondContact OE1-O 3.3Å; M338-A379 HydrophobicContact CB-CB 4.15Å; A339-A379 HydrophobicContact CB-CB 4.25Å; L375-A379 VanDerWaalsContact O-CB 3.22Å; L375-A379 WeakPolarHBondContact O-CB 3.44Å; L375-A379 PolarHBondContact O-N 3.02Å; V376-A379 PolarHBondContact O-N 2.89Å; V376-A379 VanDerWaalsContact O-N 3.16Å; D377-A379 VanDerWaalsContact C-N 3.26Å; D377-A379 PolarHBondContact O-N 3.26Å; A379-T383 WeakPolarHBondContact O-CB 3.31Å; A379-T383 PolarHBondContact O-OG1 3.25Å
380	I	98.1	Very high	97	Very high	0 Å²	0	7.3 Å²	7.3	0%	0	4%	0.036	C	C	.	.	H	α-helix	trans	-83.5	-38.6	-172.5	-64.2	-60.3	0	0	0	112.6	C273 L277 A339 V376 D377 T383 M384 M445	C273-I380 HydrophobicContact CB-CG2 3.6Å; L277-I380 HydrophobicContact CD1-CG2 4.15Å; L277-I380 HydrophobicContact CD2-CB 3.93Å; L277-I380 HydrophobicContact CD2-CG2 3.86Å; L277-I380 HydrophobicContact CG-CB 4.39Å; L277-I380 HydrophobicContact CG-CG2 3.77Å; A339-I380 HydrophobicContact CB-CD1 3.63Å; A339-I380 HydrophobicContact CB-CG1 3.76Å; V376-I380 HydrophobicContact CG1-CG1 4Å; V376-I380 WeakPolarHBondContact O-CB 3.19Å; V376-I380 VanDerWaalsContact O-CG1 3.28Å; V376-I380 WeakPolarHBondContact O-CG1 3.48Å; V376-I380 PolarHBondContact O-N 3.12Å; D377-I380 PolarHBondContact O-N 3.17Å; I380-T383 WeakPolarHBondContact O-CB 3.26Å; I380-T383 PolarHBondContact O-N 3.18Å; I380-T383 VanDerWaalsContact O-N 3.15Å; I380-M384 HydrophobicContact CG2-CG 4.22Å; I380-M384 HydrophobicContact CG2-SD 4.35Å; I380-M384 WeakPolarHBondContact O-CG 3.47Å; I380-M384 PolarHBondContact O-N 3.04Å; I380-M445 HydrophobicContact CD1-CE 3.6Å
381	L	97.8	Very high	96.8	Very high	0 Å²	0	12 Å²	12	0%	0	5%	0.052	C	C	.	.	H	α-helix	trans	-59	-43.1	179.8	-70.9	179.5	0	0	0	113.7	L190 L194 L277 D377 G385 Y400 A403 Y407	L190-L381 HydrophobicContact CD1-CB 4.24Å; L194-L381 HydrophobicContact CD1-CD1 4.06Å; L194-L381 HydrophobicContact CD2-CD1 3.83Å; L194-L381 HydrophobicContact CG-CD1 4.16Å; L277-L381 HydrophobicContact CD1-CD2 4.14Å; D377-L381 WeakPolarHBondContact O-CG 3.49Å; D377-L381 PolarHBondContact O-N 3.41Å; D377-L381 VanDerWaalsContact O-N 3.14Å; L381-G385 PolarHBondContact O-N 3.36Å; L381-Y400 HydrophobicContact CB-CE1 4.3Å; L381-Y400 HydrophobicContact CD2-CD1 4.23Å; L381-Y400 HydrophobicContact CD2-CE1 4.17Å; L381-Y400 PolarHBondContact O-OH 3.15Å; L381-A403 HydrophobicContact CD2-CB 3.62Å; L381-Y407 HydrophobicContact CD2-CE2 4.29Å
382	P	96.9	Very high	96.7	Very high	0 Å²	0	11.6 Å²	11.6	0%	0	5%	0.052	C	C	.	.	H	α-helix	trans	-69.9	-37.9	173.4	-16.2	30.8	0	0	0	112.3	R186 T187 L190 T378 M384 G385 F386	R186-P382 PolarHBondContact NH2-O 3.16Å; T187-P382 HydrophobicContact CG2-CG 4.07Å; T187-P382 WeakPolarHBondContact OG1-CB 3.42Å; L190-P382 HydrophobicContact CD1-CB 4.28Å; L190-P382 HydrophobicContact CD1-CG 3.98Å; T378-P382 WeakPolarHBondContact O-CD 3.43Å; T378-P382 VanDerWaalsContact O-CG 3.29Å; T378-P382 WeakPolarHBondContact O-CG 3.45Å; P382-M384 VanDerWaalsContact C-N 3.27Å; P382-M384 PolarHBondContact O-N 3.34Å; P382-G385 PolarHBondContact O-N 2.86Å; P382-G385 VanDerWaalsContact O-N 3.11Å; P382-F386 PolarHBondContact O-N 2.93Å
383	T	96.6	Very high	96.5	Very high	0 Å²	0	13.9 Å²	13.9	0%	0	7%	0.066	C	C	.	.	H	α-helix	trans	-57	-41.1	175.3	-61.5	0	0	0	0	111.2	Q335 A379 I380 G385 F386 L387 Y452	Q335-T383 PolarHBondContact OE1-OG1 3.26Å; A379-T383 WeakPolarHBondContact O-CB 3.31Å; A379-T383 PolarHBondContact O-OG1 3.25Å; I380-T383 WeakPolarHBondContact O-CB 3.26Å; I380-T383 PolarHBondContact O-N 3.18Å; I380-T383 VanDerWaalsContact O-N 3.15Å; T383-G385 PolarHBondContact O-N 3.29Å; T383-F386 WeakPolarHBondContact O-CB 3.22Å; T383-F386 PolarHBondContact O-N 3.3Å; T383-L387 HydrophobicContact CG2-CD1 4.31Å; T383-L387 HydrophobicContact CG2-CG 4.44Å; T383-L387 VanDerWaalsContact O-CG 3.32Å; T383-L387 WeakPolarHBondContact O-CG 3.42Å; T383-L387 PolarHBondContact O-N 3.34Å; T383-Y452 WeakPolarHBondContact CA-OH 3.42Å; T383-Y452 HydrophobicContact CG2-CE2 4.16Å; T383-Y452 PolarHBondContact OG1-OH 2.87Å; T383-Y452 VanDerWaalsContact OG1-OH 3.06Å
384	M	97.5	Very high	96.3	Very high	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-62.1	-43.2	175.8	-73	-174.8	84.1	0	0	112.3	I270 C273 L277 I380 P382 F386 L387 V388 V399 I402 A403	I270-M384 HydrophobicContact CG2-CE 3.86Å; C273-M384 HydrophobicContact CB-CG 3.54Å; C273-M384 HydrophobicContact CB-SD 4.04Å; L277-M384 HydrophobicContact CD1-SD 3.85Å; I380-M384 HydrophobicContact CG2-CG 4.22Å; I380-M384 HydrophobicContact CG2-SD 4.35Å; I380-M384 WeakPolarHBondContact O-CG 3.47Å; I380-M384 PolarHBondContact O-N 3.04Å; P382-M384 VanDerWaalsContact C-N 3.27Å; P382-M384 PolarHBondContact O-N 3.34Å; M384-F386 VanDerWaalsContact C-N 3.3Å; M384-F386 PolarHBondContact O-N 3.01Å; M384-L387 PolarHBondContact O-N 3.49Å; M384-V388 PolarHBondContact O-N 3.32Å; M384-V399 HydrophobicContact CB-CG2 3.84Å; M384-V399 HydrophobicContact CE-CG2 3.79Å; M384-I402 HydrophobicContact CE-CB 4.12Å; M384-I402 HydrophobicContact CE-CG2 3.84Å; M384-A403 HydrophobicContact CE-CB 4.36Å; M384-A403 HydrophobicContact SD-CB 3.95Å
385	G	96.2	Very high	96.2	Very high	0 Å²	0	15.7 Å²	15.7	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-59.7	-41.4	172.5	0	0	0	0	0	112.1	L381 P382 T383 V388 D389	L381-G385 PolarHBondContact O-N 3.36Å; P382-G385 PolarHBondContact O-N 2.86Å; P382-G385 VanDerWaalsContact O-N 3.11Å; T383-G385 PolarHBondContact O-N 3.29Å; G385-V388 PolarHBondContact O-N 3.26Å; G385-D389 VanDerWaalsContact O-CG 3.31Å; G385-D389 PolarHBondContact O-N 3.44Å
386	F	95.5	Very high	96.1	Very high	13 Å²	13	15.9 Å²	15.9	6%	0.057	8%	0.079	C	C	.	.	H	α-helix	trans	-65.2	-40.1	179.1	176.8	-89.6	0	0	0	112.4	P382 T383 M384 V388 D389 T390 C451 Y452 R456	P382-F386 PolarHBondContact O-N 2.93Å; T383-F386 WeakPolarHBondContact O-CB 3.22Å; T383-F386 PolarHBondContact O-N 3.3Å; M384-F386 VanDerWaalsContact C-N 3.3Å; M384-F386 PolarHBondContact O-N 3.01Å; F386-V388 VanDerWaalsContact C-N 3.29Å; F386-V388 PolarHBondContact O-N 2.97Å; F386-D389 PolarHBondContact O-N 3.19Å; F386-T390 HydrophobicContact CD1-CG2 4.29Å; F386-T390 HydrophobicContact CD2-CG2 4.43Å; F386-T390 HydrophobicContact CE1-CG2 3.74Å; F386-T390 HydrophobicContact CE2-CG2 3.91Å; F386-T390 HydrophobicContact CZ-CG2 3.53Å; F386-T390 WeakPolarHBondContact O-CG2 3.32Å; F386-T390 PolarHBondContact O-N 3.33Å; F386-T390 PolarHBondContact O-OG1 2.77Å; F386-C451 WeakPolarHBondContact CE1-O 3.44Å; F386-Y452 HydrophobicContact CB-CE1 4.37Å; F386-Y452 HydrophobicContact CD1-CD1 4.11Å; F386-Y452 AromaticContact CD1-CE1 3.94Å; F386-Y452 HydrophobicContact CD1-CE1 3.94Å; F386-Y452 HydrophobicContact CD2-CD1 4.18Å; F386-Y452 AromaticContact CD2-CE1 3.86Å; F386-Y452 HydrophobicContact CD2-CE1 3.86Å; F386-Y452 AromaticContact CE1-CD1 3.89Å; F386-Y452 HydrophobicContact CE1-CD1 3.89Å; F386-Y452 HydrophobicContact CE1-CE1 4.2Å; F386-Y452 HydrophobicContact CE1-CG 4.27Å; F386-Y452 AromaticContact CE2-CD1 3.97Å; F386-Y452 HydrophobicContact CE2-CD1 3.97Å; F386-Y452 HydrophobicContact CE2-CE1 4.13Å; F386-Y452 HydrophobicContact CG-CD1 4.26Å; F386-Y452 AromaticContact CG-CE1 3.78Å; F386-Y452 HydrophobicContact CG-CE1 3.78Å; F386-Y452 AromaticContact CZ-CD1 3.81Å; F386-Y452 HydrophobicContact CZ-CD1 3.81Å; F386-Y452 HydrophobicContact CZ-CE1 4.29Å; F386-Y452 HydrophobicContact CZ-CG 4.46Å; F386-R456 HydrophobicContact CE2-CG 4.08Å
387	L	95.5	Very high	96.1	Very high	1 Å²	1	15.9 Å²	15.9	1%	0.005	8%	0.079	C	C	.	.	H	α-helix	trans	-62.8	-38.2	175.8	-72	172.1	0	0	0	111.7	Y269 I270 T383 M384 T390 R391 C451	Y269-L387 HydrophobicContact CD2-CD2 3.73Å; Y269-L387 HydrophobicContact CG-CD2 4.16Å; I270-L387 HydrophobicContact CG1-CB 4.11Å; I270-L387 HydrophobicContact CG1-CD1 4.08Å; T383-L387 HydrophobicContact CG2-CD1 4.31Å; T383-L387 HydrophobicContact CG2-CG 4.44Å; T383-L387 VanDerWaalsContact O-CG 3.32Å; T383-L387 WeakPolarHBondContact O-CG 3.42Å; T383-L387 PolarHBondContact O-N 3.34Å; M384-L387 PolarHBondContact O-N 3.49Å; L387-T390 PolarHBondContact O-OG1 3.49Å; L387-R391 VanDerWaalsContact O-CB 3.29Å; L387-R391 WeakPolarHBondContact O-CB 3.41Å; L387-R391 PolarHBondContact O-N 3.42Å; L387-C451 HydrophobicContact CD2-CB 3.89Å
388	V	95.8	Very high	96.1	Very high	1 Å²	1	15.6 Å²	15.6	1%	0.006	8%	0.078	C	C	.	.	H	α-helix	trans	-66.9	-42.5	174.6	172.3	0	0	0	0	111.3	L264 I270 M384 G385 F386 T390 H392 V393 V399	L264-V388 HydrophobicContact CD2-CG2 4.44Å; I270-V388 HydrophobicContact CD1-CG2 4.22Å; M384-V388 PolarHBondContact O-N 3.32Å; G385-V388 PolarHBondContact O-N 3.26Å; F386-V388 VanDerWaalsContact C-N 3.29Å; F386-V388 PolarHBondContact O-N 2.97Å; V388-T390 VanDerWaalsContact C-N 3.3Å; V388-T390 PolarHBondContact O-N 3.42Å; V388-H392 HydrophobicContact CG1-CB 4.34Å; V388-H392 CarbonylContact O-C 3.11Å; V388-H392 WeakPolarHBondContact O-CA 3.36Å; V388-H392 PolarHBondContact O-N 3.39Å; V388-V393 WeakPolarHBondContact CG1-O 3.5Å; V388-V399 HydrophobicContact CG2-CB 3.6Å; V388-V399 HydrophobicContact CG2-CG1 3.78Å; V388-V399 HydrophobicContact CG2-CG2 3.65Å
389	D	94.5	Very high	96.1	Very high	18 Å²	18	15.6 Å²	15.6	10%	0.096	8%	0.078	C	C	.	.	H	α-helix	trans	-62.9	-34.7	178.8	-69.1	-34.7	0	0	0	113.8	R186 G385 F386 S394 Y396 R456	R186-D389 IonicContact CZ-OD2 2.65Å; R186-D389 IonicContact NH1-OD2 2.79Å; R186-D389 PolarHBondContact NH1-OD2 3.42Å; R186-D389 IonicContact NH2-OD2 3.99Å; G385-D389 VanDerWaalsContact O-CG 3.31Å; G385-D389 PolarHBondContact O-N 3.44Å; F386-D389 PolarHBondContact O-N 3.19Å; D389-S394 VanDerWaalsContact OD1-CB 3.28Å; D389-S394 WeakPolarHBondContact OD1-CB 3.24Å; D389-S394 PolarHBondContact OD1-OG 3.05Å; D389-Y396 PolarHBondContact OD1-OH 3.43Å; D389-R456 IonicContact OD2-CZ 3.66Å; D389-R456 IonicContact OD2-NE 3.7Å; D389-R456 IonicContact OD2-NH1 3.56Å; D389-R456 IonicContact OD2-NH2 3.59Å
390	T	92.7	Very high	96.1	Very high	30 Å²	30	15.6 Å²	15.6	18%	0.184	8%	0.078	C	C	.	.	H	α-helix	trans	-93.4	-29.6	-174	49.9	0	0	0	0	113.6	F386 L387 V388 V454 R456	F386-T390 HydrophobicContact CD1-CG2 4.29Å; F386-T390 HydrophobicContact CD2-CG2 4.43Å; F386-T390 HydrophobicContact CE1-CG2 3.74Å; F386-T390 HydrophobicContact CE2-CG2 3.91Å; F386-T390 HydrophobicContact CZ-CG2 3.53Å; F386-T390 WeakPolarHBondContact O-CG2 3.32Å; F386-T390 PolarHBondContact O-N 3.33Å; F386-T390 PolarHBondContact O-OG1 2.77Å; L387-T390 PolarHBondContact O-OG1 3.49Å; V388-T390 VanDerWaalsContact C-N 3.3Å; V388-T390 PolarHBondContact O-N 3.42Å; T390-V454 HydrophobicContact CG2-CG1 4.49Å; T390-R456 HydrophobicContact CG2-CG 4Å
391	R	93.9	Very high	96.1	Very high	111 Å²	111	15.6 Å²	15.6	42%	0.419	8%	0.078	S	C	.	.	H	α-helix	trans	-116.7	-17.5	-171.8	-56.7	-176.3	62.9	170.3	-4.5	114.3	D267 L387	D267-R391 IonicContact OD1-CZ 3.47Å; D267-R391 IonicContact OD1-NH1 3.18Å; D267-R391 PolarHBondContact OD1-NH1 3.27Å; D267-R391 IonicContact OD1-NH2 3.82Å; D267-R391 IonicContact OD2-CZ 3.13Å; D267-R391 IonicContact OD2-NE 3.17Å; D267-R391 PolarHBondContact OD2-NE 3.48Å; D267-R391 IonicContact OD2-NH1 3.66Å; D267-R391 IonicContact OD2-NH2 3.34Å; D267-R391 PolarHBondContact OD2-NH2 3Å; L387-R391 VanDerWaalsContact O-CB 3.29Å; L387-R391 WeakPolarHBondContact O-CB 3.41Å; L387-R391 PolarHBondContact O-N 3.42Å
392	H	94.9	Very high	96.2	Very high	51 Å²	51	15.7 Å²	15.7	24%	0.236	8%	0.078	C	C	.	.	S	Bend	trans	-135.3	-165.3	-173.7	-61.9	-75.6	0	0	0	110.3	L264 D267 V388	L264-H392 HydrophobicContact CD2-CB 3.95Å; L264-H392 VanDerWaalsContact CD2-CG 3.43Å; D267-H392 IonicContact OD2-CD2 3.85Å; D267-H392 IonicContact OD2-CE1 3.68Å; D267-H392 IonicContact OD2-NE2 2.82Å; D267-H392 PolarHBondContact OD2-NE2 3.4Å; V388-H392 HydrophobicContact CG1-CB 4.34Å; V388-H392 CarbonylContact O-C 3.11Å; V388-H392 WeakPolarHBondContact O-CA 3.36Å; V388-H392 PolarHBondContact O-N 3.39Å
393	V	93.6	Very high	96.3	Very high	49 Å²	49	15.7 Å²	15.7	30%	0.297	8%	0.078	S	C	.	.			trans	-88.3	127	174.3	-171.2	0	0	0	0	108.8	P256 T259 V388 V395	P256-V393 HydrophobicContact CB-CG1 3.7Å; T259-V393 PolarHBondContact OG1-N 3.12Å; V388-V393 WeakPolarHBondContact CG1-O 3.5Å; V393-V395 HydrophobicContact CG1-CG2 4.07Å; V393-V395 PolarHBondContact O-N 3.23Å
394	S	93.6	Very high	96.3	Very high	35 Å²	35	16.1 Å²	16.1	25%	0.245	8%	0.081	C	C	.	.	S	Bend	trans	-59.7	67.6	175.3	-57.6	0	0	0	0	113.8	D389	D389-S394 VanDerWaalsContact OD1-CB 3.28Å; D389-S394 WeakPolarHBondContact OD1-CB 3.24Å; D389-S394 PolarHBondContact OD1-OG 3.05Å
395	V	96.3	Very high	96.3	Very high	7 Å²	7	17.5 Å²	17.5	4%	0.042	9%	0.088	C	C	.	.			trans	-132.6	121.1	170.6	-176.3	0	0	0	0	105.7	D123 P256 V393	D123-V395 HydrophobicContact CB-CG1 3.91Å; D123-V395 WeakPolarHBondContact OD1-CG1 3.34Å; P256-V395 HydrophobicContact CB-CG2 4.14Å; P256-V395 HydrophobicContact CG-CG2 4.11Å; V393-V395 HydrophobicContact CG1-CG2 4.07Å; V393-V395 PolarHBondContact O-N 3.23Å
396	Y	97.4	Very high	96.4	Very high	11 Å²	11	17.7 Å²	17.7	4%	0.043	9%	0.089	C	C	.	.			trans	-100.5	-7	-159	-55.3	-79.2	0	0	0	114.9	A177 D178 D389 S398 V399 Y400	A177-Y396 HydrophobicContact CB-CD1 3.95Å; A177-Y396 HydrophobicContact CB-CD2 4.15Å; A177-Y396 HydrophobicContact CB-CE1 4.27Å; A177-Y396 HydrophobicContact CB-CE2 4.47Å; A177-Y396 HydrophobicContact CB-CG 3.87Å; D178-Y396 HydrophobicContact CB-CD2 3.97Å; D178-Y396 HydrophobicContact CB-CE2 4.12Å; D389-Y396 PolarHBondContact OD1-OH 3.43Å; Y396-S398 PolarHBondContact O-N 3.18Å; Y396-V399 HydrophobicContact CD1-CG1 4.45Å; Y396-V399 VanDerWaalsContact O-CG1 3.26Å; Y396-V399 WeakPolarHBondContact O-CG1 3.33Å; Y396-V399 PolarHBondContact O-N 3.37Å; Y396-Y400 HydrophobicContact CD1-CE2 4.32Å; Y396-Y400 HydrophobicContact CG-CE2 4.38Å; Y396-Y400 VanDerWaalsContact O-CD2 3.31Å; Y396-Y400 WeakPolarHBondContact O-CD2 3.27Å; Y396-Y400 PolarHBondContact O-N 3.44Å; Y396-Y400 VanDerWaalsContact O-N 3.1Å
397	G	97.3	Very high	96.5	Very high	0 Å²	0	18.5 Å²	18.5	0%	0	9%	0.092	C	C	.	.	H	α-helix	trans	-60	-52.1	-175.4	0	0	0	0	0	112.3	D123 T170 V399 A401	D123-G397 WeakPolarHBondContact OD1-CA 2.91Å; D123-G397 PolarHBondContact OD1-N 2.69Å; T170-G397 WeakPolarHBondContact CG2-O 3.49Å; G397-V399 VanDerWaalsContact C-N 3.34Å; G397-V399 PolarHBondContact O-N 3.4Å; G397-A401 WeakPolarHBondContact O-CB 3.28Å; G397-A401 PolarHBondContact O-N 2.69Å
398	S	98.2	Very high	96.5	Very high	1 Å²	1	18.6 Å²	18.6	1%	0.007	9%	0.093	C	C	.	.	H	α-helix	trans	-64.2	-32.5	179	-70.9	0	0	0	0	114	D123 Y396 I402	D123-S398 PolarHBondContact OD1-N 2.87Å; D123-S398 VanDerWaalsContact OD2-CB 3.23Å; D123-S398 WeakPolarHBondContact OD2-CB 3.4Å; D123-S398 PolarHBondContact OD2-N 3.26Å; D123-S398 PolarHBondContact OD2-OG 2.85Å; Y396-S398 PolarHBondContact O-N 3.18Å; S398-I402 WeakPolarHBondContact O-CG1 3.25Å; S398-I402 PolarHBondContact O-N 2.9Å; S398-I402 VanDerWaalsContact O-N 3.17Å
399	V	98.4	Very high	96.5	Very high	0 Å²	0	21.3 Å²	21.3	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-76.2	-39.5	-178.9	71	0	0	0	0	112.5	L264 I270 M384 V388 Y396 G397 A401 I402 A403	L264-V399 HydrophobicContact CD1-CB 4.34Å; I270-V399 HydrophobicContact CG2-CG2 4.44Å; M384-V399 HydrophobicContact CB-CG2 3.84Å; M384-V399 HydrophobicContact CE-CG2 3.79Å; V388-V399 HydrophobicContact CG2-CB 3.6Å; V388-V399 HydrophobicContact CG2-CG1 3.78Å; V388-V399 HydrophobicContact CG2-CG2 3.65Å; Y396-V399 HydrophobicContact CD1-CG1 4.45Å; Y396-V399 VanDerWaalsContact O-CG1 3.26Å; Y396-V399 WeakPolarHBondContact O-CG1 3.33Å; Y396-V399 PolarHBondContact O-N 3.37Å; G397-V399 VanDerWaalsContact C-N 3.34Å; G397-V399 PolarHBondContact O-N 3.4Å; V399-A401 VanDerWaalsContact C-N 3.29Å; V399-I402 WeakPolarHBondContact O-CB 3.44Å; V399-I402 PolarHBondContact O-N 3.2Å; V399-A403 PolarHBondContact O-N 3.04Å; V399-A403 VanDerWaalsContact O-N 3.11Å
400	Y	98.3	Very high	96.5	Very high	0 Å²	0	20.5 Å²	20.5	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-74.7	-22.8	173.8	-71.8	-68.1	0	0	0	112.1	L173 A174 A177 L190 L381 Y396 I402 A403 D404	L173-Y400 HydrophobicContact CB-CD1 3.69Å; L173-Y400 HydrophobicContact CB-CD2 4.34Å; L173-Y400 HydrophobicContact CB-CE1 4.28Å; L173-Y400 HydrophobicContact CB-CG 3.73Å; L173-Y400 HydrophobicContact CD1-CD1 4.15Å; A174-Y400 VanDerWaalsContact CA-CD2 3.5Å; A174-Y400 HydrophobicContact CB-CD2 3.97Å; A177-Y400 HydrophobicContact CB-CD2 4.4Å; A177-Y400 HydrophobicContact CB-CE2 3.33Å; L190-Y400 HydrophobicContact CD1-CE1 4.41Å; L190-Y400 WeakPolarHBondContact CD1-OH 3.5Å; L381-Y400 HydrophobicContact CB-CE1 4.3Å; L381-Y400 HydrophobicContact CD2-CD1 4.23Å; L381-Y400 HydrophobicContact CD2-CE1 4.17Å; L381-Y400 PolarHBondContact O-OH 3.15Å; Y396-Y400 HydrophobicContact CD1-CE2 4.32Å; Y396-Y400 HydrophobicContact CG-CE2 4.38Å; Y396-Y400 VanDerWaalsContact O-CD2 3.31Å; Y396-Y400 WeakPolarHBondContact O-CD2 3.27Å; Y396-Y400 PolarHBondContact O-N 3.44Å; Y396-Y400 VanDerWaalsContact O-N 3.1Å; Y400-I402 VanDerWaalsContact C-N 3.3Å; Y400-A403 HydrophobicContact CD1-CB 4.46Å; Y400-A403 WeakPolarHBondContact O-CB 3.13Å; Y400-A403 PolarHBondContact O-N 2.89Å; Y400-D404 WeakPolarHBondContact O-CB 3.45Å; Y400-D404 PolarHBondContact O-N 3.35Å
401	A	98.4	Very high	96.5	Very high	0 Å²	0	21.4 Å²	21.4	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-64.4	-37.5	167.2	0	0	0	0	0	111.2	N115 T170 I261 G397 V399 D404 I405	N115-A401 WeakPolarHBondContact O-CB 3.28Å; T170-A401 HydrophobicContact CG2-CB 3.77Å; I261-A401 HydrophobicContact CD1-CB 4.19Å; G397-A401 WeakPolarHBondContact O-CB 3.28Å; G397-A401 PolarHBondContact O-N 2.69Å; V399-A401 VanDerWaalsContact C-N 3.29Å; A401-D404 PolarHBondContact O-N 3.43Å; A401-I405 WeakPolarHBondContact O-CB 3.42Å; A401-I405 WeakPolarHBondContact O-CD1 3.46Å; A401-I405 WeakPolarHBondContact O-CG1 3.34Å; A401-I405 PolarHBondContact O-N 3.14Å
402	I	98.5	Very high	96.4	Very high	1 Å²	1	16.3 Å²	16.3	1%	0.005	8%	0.084	C	C	.	.	H	α-helix	trans	-65.1	-42	173.7	-66.8	166.2	0	0	0	110.6	I261 L264 L265 I270 A274 M384 S398 V399 Y400 D404 I405 S406	I261-I402 HydrophobicContact CD1-CG1 4.08Å; I261-I402 HydrophobicContact CG1-CD1 4.01Å; I261-I402 HydrophobicContact CG1-CG1 3.82Å; L264-I402 HydrophobicContact CB-CD1 3.61Å; L265-I402 HydrophobicContact CD2-CB 4.46Å; L265-I402 HydrophobicContact CD2-CD1 3.92Å; L265-I402 HydrophobicContact CD2-CG1 3.78Å; L265-I402 HydrophobicContact CD2-CG2 3.87Å; L265-I402 HydrophobicContact CG-CD1 3.8Å; L265-I402 HydrophobicContact CG-CG1 3.96Å; I270-I402 HydrophobicContact CG2-CD1 4.06Å; I270-I402 HydrophobicContact CG2-CG2 4.35Å; A274-I402 HydrophobicContact CB-CG2 3.57Å; M384-I402 HydrophobicContact CE-CB 4.12Å; M384-I402 HydrophobicContact CE-CG2 3.84Å; S398-I402 WeakPolarHBondContact O-CG1 3.25Å; S398-I402 PolarHBondContact O-N 2.9Å; S398-I402 VanDerWaalsContact O-N 3.17Å; V399-I402 WeakPolarHBondContact O-CB 3.44Å; V399-I402 PolarHBondContact O-N 3.2Å; Y400-I402 VanDerWaalsContact C-N 3.3Å; I402-D404 VanDerWaalsContact C-N 3.33Å; I402-D404 PolarHBondContact O-N 3.5Å; I402-I405 WeakPolarHBondContact O-CB 3.46Å; I402-I405 PolarHBondContact O-N 2.89Å; I402-S406 PolarHBondContact O-N 2.92Å; I402-S406 PolarHBondContact O-OG 2.92Å
403	A	98.4	Very high	96.1	Very high	0 Å²	0	17.9 Å²	17.9	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-60.4	-44.2	174.2	0	0	0	0	0	111.6	L277 L381 M384 V399 Y400 I405 S406 Y407	L277-A403 HydrophobicContact CD1-CB 3.73Å; L381-A403 HydrophobicContact CD2-CB 3.62Å; M384-A403 HydrophobicContact CE-CB 4.36Å; M384-A403 HydrophobicContact SD-CB 3.95Å; V399-A403 PolarHBondContact O-N 3.04Å; V399-A403 VanDerWaalsContact O-N 3.11Å; Y400-A403 HydrophobicContact CD1-CB 4.46Å; Y400-A403 WeakPolarHBondContact O-CB 3.13Å; Y400-A403 PolarHBondContact O-N 2.89Å; A403-I405 PolarHBondContact O-N 3.26Å; A403-S406 VanDerWaalsContact O-CB 3.26Å; A403-S406 WeakPolarHBondContact O-CB 3.12Å; A403-S406 PolarHBondContact O-N 3.03Å; A403-S406 VanDerWaalsContact O-N 3.08Å; A403-Y407 HydrophobicContact CB-CE2 4.49Å; A403-Y407 WeakPolarHBondContact O-CD2 3.5Å; A403-Y407 PolarHBondContact O-N 3.24Å; A403-Y407 VanDerWaalsContact O-N 3.12Å
404	D	97.5	Very high	95.7	Very high	9 Å²	9	15.5 Å²	15.5	5%	0.048	8%	0.08	C	C	.	.	H	α-helix	trans	-69.6	-32.1	179.3	-161.4	44.6	0	0	0	113.2	Q111 N115 Y400 A401 I402 S406 Y407 S408	Q111-D404 WeakPolarHBondContact CG-OD2 3.44Å; Q111-D404 VanDerWaalsContact NE2-CG 3.3Å; Q111-D404 PolarHBondContact NE2-OD1 2.89Å; Q111-D404 PolarHBondContact NE2-OD2 3.24Å; N115-D404 VanDerWaalsContact CG-OD2 3.25Å; N115-D404 VanDerWaalsContact ND2-C 3.35Å; N115-D404 WeakPolarHBondContact ND2-CB 3.4Å; N115-D404 VanDerWaalsContact ND2-CG 3.32Å; N115-D404 PolarHBondContact ND2-OD2 2.94Å; N115-D404 PolarHBondContact OD1-OD2 3.42Å; Y400-D404 WeakPolarHBondContact O-CB 3.45Å; Y400-D404 PolarHBondContact O-N 3.35Å; A401-D404 PolarHBondContact O-N 3.43Å; I402-D404 VanDerWaalsContact C-N 3.33Å; I402-D404 PolarHBondContact O-N 3.5Å; D404-S406 VanDerWaalsContact C-N 3.31Å; D404-S406 PolarHBondContact O-N 3.11Å; D404-Y407 PolarHBondContact O-N 3.43Å; D404-S408 WeakPolarHBondContact O-CB 3.43Å; D404-S408 PolarHBondContact O-N 2.85Å; D404-S408 PolarHBondContact O-OG 3.16Å
405	I	98.2	Very high	95.2	Very high	30 Å²	30	15.1 Å²	15.1	15%	0.154	8%	0.076	C	C	.	.	H	α-helix	trans	-58.4	-44.1	167	-75.5	163.5	0	0	0	110.4	L112 N115 P116 I261 A401 I402 A403 S408 L409	L112-I405 HydrophobicContact CD1-CB 4.26Å; L112-I405 HydrophobicContact CD1-CG1 4.42Å; L112-I405 HydrophobicContact CD1-CG2 3.73Å; N115-I405 HydrophobicContact CB-CD1 3.95Å; N115-I405 HydrophobicContact CB-CG1 3.43Å; N115-I405 VanDerWaalsContact CB-CG1 3.43Å; N115-I405 PolarHBondContact ND2-N 3.24Å; P116-I405 HydrophobicContact CG-CD1 3.88Å; I261-I405 HydrophobicContact CD1-CD1 4.22Å; A401-I405 WeakPolarHBondContact O-CB 3.42Å; A401-I405 WeakPolarHBondContact O-CD1 3.46Å; A401-I405 WeakPolarHBondContact O-CG1 3.34Å; A401-I405 PolarHBondContact O-N 3.14Å; I402-I405 WeakPolarHBondContact O-CB 3.46Å; I402-I405 PolarHBondContact O-N 2.89Å; A403-I405 PolarHBondContact O-N 3.26Å; I405-S408 PolarHBondContact O-N 2.88Å; I405-L409 WeakPolarHBondContact O-CB 3.18Å; I405-L409 PolarHBondContact O-N 3.37Å
406	S	98	Very high	94.7	Very high	4 Å²	4	19.7 Å²	19.7	3%	0.028	10%	0.1	C	C	.	.	H	α-helix	trans	-61.6	-46.6	178.7	-64	0	0	0	0	112.5	A274 T278 I402 A403 D404 A410	A274-S406 VanDerWaalsContact C-OG 3.29Å; A274-S406 VanDerWaalsContact CA-OG 3.26Å; A274-S406 WeakPolarHBondContact CA-OG 3.45Å; A274-S406 WeakPolarHBondContact CB-OG 3.41Å; A274-S406 VanDerWaalsContact O-CB 3.29Å; A274-S406 WeakPolarHBondContact O-CB 3.32Å; A274-S406 PolarHBondContact O-OG 3.44Å; T278-S406 WeakPolarHBondContact OG1-CA 3.48Å; T278-S406 WeakPolarHBondContact OG1-CB 3.48Å; T278-S406 PolarHBondContact OG1-OG 2.79Å; I402-S406 PolarHBondContact O-N 2.92Å; I402-S406 PolarHBondContact O-OG 2.92Å; A403-S406 VanDerWaalsContact O-CB 3.26Å; A403-S406 WeakPolarHBondContact O-CB 3.12Å; A403-S406 PolarHBondContact O-N 3.03Å; A403-S406 VanDerWaalsContact O-N 3.08Å; D404-S406 VanDerWaalsContact C-N 3.31Å; D404-S406 PolarHBondContact O-N 3.11Å; S406-A410 PolarHBondContact O-N 3.01Å
407	Y	96.3	Very high	94.1	Very high	30 Å²	30	22.2 Å²	22.2	12%	0.118	12%	0.116	C	C	.	.	H	α-helix	trans	-61.6	-50.8	175.1	-64.6	-57.5	0	0	0	111	L277 N281 D377 L381 A403 D404 L409 A410 Y411	L277-Y407 HydrophobicContact CD2-CE1 4.29Å; L277-Y407 WeakPolarHBondContact CD2-OH 3.32Å; N281-Y407 HydrophobicContact CB-CD1 4.28Å; N281-Y407 WeakPolarHBondContact ND2-CD1 3.39Å; N281-Y407 WeakPolarHBondContact ND2-CE1 3.29Å; D377-Y407 VanDerWaalsContact CG-OH 3.3Å; D377-Y407 WeakPolarHBondContact OD1-CE1 3.37Å; D377-Y407 PolarHBondContact OD1-OH 3.14Å; L381-Y407 HydrophobicContact CD2-CE2 4.29Å; A403-Y407 HydrophobicContact CB-CE2 4.49Å; A403-Y407 WeakPolarHBondContact O-CD2 3.5Å; A403-Y407 PolarHBondContact O-N 3.24Å; A403-Y407 VanDerWaalsContact O-N 3.12Å; D404-Y407 PolarHBondContact O-N 3.43Å; Y407-L409 VanDerWaalsContact C-N 3.28Å; Y407-L409 PolarHBondContact O-N 3.42Å; Y407-A410 WeakPolarHBondContact O-CB 3.29Å; Y407-A410 PolarHBondContact O-N 3.01Å; Y407-A410 VanDerWaalsContact O-N 3.17Å; Y407-Y411 WeakPolarHBondContact O-CD2 3.28Å; Y407-Y411 PolarHBondContact O-N 2.94Å; Y407-Y411 VanDerWaalsContact O-N 3.1Å
408	S	96	Very high	93.5	Very high	3 Å²	3	22.2 Å²	22.2	2%	0.021	12%	0.116	C	C	.	.	H	α-helix	trans	-62.8	-34.9	-177.6	-60.2	0	0	0	0	112.5	Q111 D404 I405 Y411 A412	Q111-S408 VanDerWaalsContact CG-OG 3.24Å; Q111-S408 WeakPolarHBondContact CG-OG 3.28Å; D404-S408 WeakPolarHBondContact O-CB 3.43Å; D404-S408 PolarHBondContact O-N 2.85Å; D404-S408 PolarHBondContact O-OG 3.16Å; I405-S408 PolarHBondContact O-N 2.88Å; S408-Y411 PolarHBondContact O-N 3.25Å; S408-A412 WeakPolarHBondContact O-CB 3.4Å; S408-A412 PolarHBondContact O-N 3.21Å
409	L	95.8	Very high	92.3	Very high	57 Å²	57	24 Å²	24	30%	0.298	13%	0.134	S	C	.	.	H	α-helix	trans	-63.7	-43.9	176.6	-177.4	63	0	0	0	111.4	L112 T278 I405 Y407 L413	L112-L409 HydrophobicContact CD1-CB 4.09Å; L112-L409 HydrophobicContact CD2-CD1 4.07Å; T278-L409 HydrophobicContact CG2-CD2 3.95Å; T278-L409 HydrophobicContact CG2-CG 4.3Å; I405-L409 WeakPolarHBondContact O-CB 3.18Å; I405-L409 PolarHBondContact O-N 3.37Å; Y407-L409 VanDerWaalsContact C-N 3.28Å; Y407-L409 PolarHBondContact O-N 3.42Å; L409-L413 HydrophobicContact CD1-CD1 3.62Å; L409-L413 HydrophobicContact CD1-CG 4.04Å; L409-L413 HydrophobicContact CG-CD1 4.09Å; L409-L413 WeakPolarHBondContact O-CB 3.35Å; L409-L413 WeakPolarHBondContact O-CG 3.42Å; L409-L413 PolarHBondContact O-N 2.97Å
410	A	94.7	Very high	91.5	Very high	1 Å²	1	26 Å²	26	1%	0.008	16%	0.155	C	C	.	.	H	α-helix	trans	-61.1	-50.7	175.7	0	0	0	0	0	111.4	N281 V282 A285 S406 Y407 A412 G414	N281-A410 HydrophobicContact CB-CB 3.86Å; V282-A410 HydrophobicContact CB-CB 4.35Å; A285-A410 HydrophobicContact CB-CB 4.37Å; A285-A410 VanDerWaalsContact CB-O 3.29Å; A285-A410 WeakPolarHBondContact CB-O 3.43Å; S406-A410 PolarHBondContact O-N 3.01Å; Y407-A410 WeakPolarHBondContact O-CB 3.29Å; Y407-A410 PolarHBondContact O-N 3.01Å; Y407-A410 VanDerWaalsContact O-N 3.17Å; A410-A412 PolarHBondContact O-N 3.39Å; A410-G414 PolarHBondContact O-N 3.5Å
411	Y	92.6	Very high	90.8	Very high	50 Å²	50	28 Å²	28	20%	0.196	17%	0.166	C	C	.	.	H	α-helix	trans	-73.7	-21.2	-179	-75.4	-78.1	0	0	0	114.5	A285 Y407 S408 P415	A285-Y411 HydrophobicContact CB-CD1 3.93Å; A285-Y411 HydrophobicContact CB-CE1 4.21Å; A285-Y411 HydrophobicContact CB-CG 4.25Å; Y407-Y411 WeakPolarHBondContact O-CD2 3.28Å; Y407-Y411 PolarHBondContact O-N 2.94Å; Y407-Y411 VanDerWaalsContact O-N 3.1Å; S408-Y411 PolarHBondContact O-N 3.25Å; Y411-P415 WeakPolarHBondContact O-CD 3.22Å
412	A	92.1	Very high	90.2	Very high	3 Å²	3	29.1 Å²	29.1	3%	0.025	17%	0.172	C	C	.	.	H	α-helix	trans	-77	-48.2	172.3	0	0	0	0	0	111.3	A108 I109 S408 A410 I416	A108-A412 HydrophobicContact CB-CB 4.03Å; I109-A412 HydrophobicContact CG1-CB 3.8Å; S408-A412 WeakPolarHBondContact O-CB 3.4Å; S408-A412 PolarHBondContact O-N 3.21Å; A410-A412 PolarHBondContact O-N 3.39Å; A412-I416 VanDerWaalsContact O-CD1 3.26Å; A412-I416 WeakPolarHBondContact O-CD1 3.43Å; A412-I416 WeakPolarHBondContact O-CG1 3.28Å
413	L	88	Confident	89.6	Confident	84 Å²	84	35.4 Å²	35.4	44%	0.44	21%	0.206	S	C	.	.	H	α-helix	trans	-78	-32.5	-176.1	-67.9	179.8	0	0	0	112.9	L409 I416 V417	L409-L413 HydrophobicContact CD1-CD1 3.62Å; L409-L413 HydrophobicContact CD1-CG 4.04Å; L409-L413 HydrophobicContact CG-CD1 4.09Å; L409-L413 WeakPolarHBondContact O-CB 3.35Å; L409-L413 WeakPolarHBondContact O-CG 3.42Å; L409-L413 PolarHBondContact O-N 2.97Å; L413-I416 PolarHBondContact O-N 3.24Å; L413-V417 WeakPolarHBondContact O-CB 3.4Å; L413-V417 WeakPolarHBondContact O-CG2 3.33Å; L413-V417 PolarHBondContact O-N 3.49Å
414	G	86.9	Confident	89.2	Confident	0 Å²	0	40.9 Å²	40.9	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-50.6	-68.1	-177.8	0	0	0	0	0	113.1	A410 I416 V417 A418	A410-G414 PolarHBondContact O-N 3.5Å; G414-I416 VanDerWaalsContact C-N 3.25Å; G414-I416 PolarHBondContact O-N 2.91Å; G414-V417 PolarHBondContact O-N 3.45Å; G414-A418 WeakPolarHBondContact O-CB 3.37Å; G414-A418 PolarHBondContact O-N 2.76Å
415	P	83.2	Confident	89	Confident	26 Å²	26	43.5 Å²	43.5	17%	0.169	25%	0.252	C	S	.	.	H	α-helix	trans	-59.4	-31	-178.1	-24.8	34.6	0	0	0	114.9	A105 P289 Y411	A105-P415 HydrophobicContact CB-CB 4.34Å; P289-P415 HydrophobicContact CG-CB 4.44Å; Y411-P415 WeakPolarHBondContact O-CD 3.22Å
416	I	83.8	Confident	88.7	Confident	104 Å²	104	49.5 Å²	49.5	53%	0.533	28%	0.277	S	S	.	.	H	α-helix	trans	-73.9	-46.2	-178.3	-61.8	175.9	0	0	0	111	A105 I109 A412 L413 G414	A105-I416 HydrophobicContact CB-CD1 4.35Å; A105-I416 HydrophobicContact CB-CG1 4.15Å; I109-I416 HydrophobicContact CD1-CD1 4.02Å; A412-I416 VanDerWaalsContact O-CD1 3.26Å; A412-I416 WeakPolarHBondContact O-CD1 3.43Å; A412-I416 WeakPolarHBondContact O-CG1 3.28Å; L413-I416 PolarHBondContact O-N 3.24Å; G414-I416 VanDerWaalsContact C-N 3.25Å; G414-I416 PolarHBondContact O-N 2.91Å
417	V	85.9	Confident	88.4	Confident	64 Å²	64	49.8 Å²	49.8	39%	0.388	28%	0.278	S	S	.	.	H	α-helix	trans	-86.1	-34.2	-174.6	-179.3	0	0	0	0	111.2	F286 L413 G414 G419 G420 L421	F286-V417 HydrophobicContact CE1-CB 3.8Å; F286-V417 HydrophobicContact CE1-CG1 3.82Å; F286-V417 HydrophobicContact CZ-CB 3.73Å; F286-V417 HydrophobicContact CZ-CG1 3.91Å; L413-V417 WeakPolarHBondContact O-CB 3.4Å; L413-V417 WeakPolarHBondContact O-CG2 3.33Å; L413-V417 PolarHBondContact O-N 3.49Å; G414-V417 PolarHBondContact O-N 3.45Å; V417-G419 PolarHBondContact O-N 3.5Å; V417-G420 PolarHBondContact O-N 2.8Å; V417-L421 VanDerWaalsContact O-CB 3.28Å; V417-L421 WeakPolarHBondContact O-CB 3.31Å; V417-L421 PolarHBondContact O-N 2.86Å
418	A	83.8	Confident	88.4	Confident	0 Å²	0	52.3 Å²	52.3	0%	0	29%	0.293	C	S	.	.	H	α-helix	trans	-59	-42.4	-173.4	0	0	0	0	0	113	F286 P289 T290 G414 L421 V422	F286-A418 HydrophobicContact CB-CB 4.38Å; F286-A418 HydrophobicContact CD1-CB 3.42Å; F286-A418 VanDerWaalsContact CD1-CB 3.42Å; F286-A418 HydrophobicContact CE1-CB 3.99Å; F286-A418 HydrophobicContact CG-CB 4.13Å; P289-A418 HydrophobicContact CG-CB 4.11Å; T290-A418 HydrophobicContact CG2-CB 3.64Å; G414-A418 WeakPolarHBondContact O-CB 3.37Å; G414-A418 PolarHBondContact O-N 2.76Å; A418-L421 PolarHBondContact O-N 3.4Å; A418-V422 WeakPolarHBondContact O-CB 3.33Å; A418-V422 VanDerWaalsContact O-CG2 3.32Å; A418-V422 WeakPolarHBondContact O-CG2 3.41Å; A418-V422 PolarHBondContact O-N 2.89Å
419	G	74.1	Confident	88.3	Confident	37 Å²	37	52.9 Å²	52.9	38%	0.381	30%	0.3	S	S	.	.	H	α-helix	trans	-59.3	-56	-179.7	0	0	0	0	0	112.7	V417 L421 V422 D423	V417-G419 PolarHBondContact O-N 3.5Å; G419-L421 VanDerWaalsContact C-N 3.29Å; G419-L421 PolarHBondContact O-N 3.38Å; G419-V422 PolarHBondContact O-N 3.27Å; G419-D423 PolarHBondContact O-N 3.02Å; G419-D423 VanDerWaalsContact O-N 3.15Å
420	G	81.8	Confident	88.2	Confident	42 Å²	42	50.3 Å²	50.3	43%	0.433	29%	0.286	S	S	.	.	H	α-helix	trans	-65.7	-32	179.5	0	0	0	0	0	113.4	V417 D423 T424	V417-G420 PolarHBondContact O-N 2.8Å; G420-D423 PolarHBondContact O-N 2.81Å; G420-T424 PolarHBondContact O-N 3.3Å; G420-T424 PolarHBondContact O-OG1 2.68Å
421	L	83.9	Confident	88.2	Confident	44 Å²	44	50.6 Å²	50.6	23%	0.23	29%	0.287	C	S	.	.	H	α-helix	trans	-70.2	-43.8	177.6	-165.6	57.6	0	0	0	111.2	F286 V417 A418 G419 D423 T424 I425 L430	F286-L421 HydrophobicContact CE1-CD2 4.4Å; V417-L421 VanDerWaalsContact O-CB 3.28Å; V417-L421 WeakPolarHBondContact O-CB 3.31Å; V417-L421 PolarHBondContact O-N 2.86Å; A418-L421 PolarHBondContact O-N 3.4Å; G419-L421 VanDerWaalsContact C-N 3.29Å; G419-L421 PolarHBondContact O-N 3.38Å; L421-D423 VanDerWaalsContact C-N 3.28Å; L421-D423 PolarHBondContact O-N 3.06Å; L421-T424 PolarHBondContact O-N 2.93Å; L421-T424 VanDerWaalsContact O-N 3.14Å; L421-I425 HydrophobicContact CD1-CD1 3.57Å; L421-I425 HydrophobicContact CD1-CG1 3.83Å; L421-I425 HydrophobicContact CD2-CD1 4.23Å; L421-I425 HydrophobicContact CG-CD1 3.66Å; L421-I425 HydrophobicContact CG-CG1 3.87Å; L421-I425 WeakPolarHBondContact O-CG1 3.43Å; L421-I425 PolarHBondContact O-N 3.11Å; L421-L430 HydrophobicContact CB-CD1 4.46Å; L421-L430 HydrophobicContact CD2-CD1 3.53Å; L421-L430 HydrophobicContact CG-CD1 4.1Å
422	V	85.8	Confident	88.4	Confident	23 Å²	23	51.5 Å²	51.5	14%	0.139	30%	0.295	C	S	.	.	H	α-helix	trans	-61.6	-36.9	174.8	171.3	0	0	0	0	111.8	T290 A418 G419 T424 K426 L430	T290-V422 HydrophobicContact CG2-CG2 3.57Å; A418-V422 WeakPolarHBondContact O-CB 3.33Å; A418-V422 VanDerWaalsContact O-CG2 3.32Å; A418-V422 WeakPolarHBondContact O-CG2 3.41Å; A418-V422 PolarHBondContact O-N 2.89Å; G419-V422 PolarHBondContact O-N 3.27Å; V422-T424 VanDerWaalsContact C-N 3.29Å; V422-T424 PolarHBondContact O-N 2.87Å; V422-K426 WeakPolarHBondContact O-CA 3.38Å; V422-K426 PolarHBondContact O-N 3.39Å; V422-L430 HydrophobicContact CG2-CB 4.23Å; V422-L430 HydrophobicContact CG2-CD2 3.54Å; V422-L430 HydrophobicContact CG2-CG 4.42Å
423	D	84.9	Confident	88.5	Confident	133 Å²	133	53.8 Å²	53.8	71%	0.711	31%	0.309	S	S	*	.	H	α-helix	trans	-66.5	-33.1	177.3	-70.4	-23.5	0	0	0	112.3	G419 G420 L421	G419-D423 PolarHBondContact O-N 3.02Å; G419-D423 VanDerWaalsContact O-N 3.15Å; G420-D423 PolarHBondContact O-N 2.81Å; L421-D423 VanDerWaalsContact C-N 3.28Å; L421-D423 PolarHBondContact O-N 3.06Å
424	T	90.1	Very high	88.9	Confident	115 Å²	115	50.2 Å²	50.2	71%	0.706	29%	0.29	S	S	*	.	H	α-helix	trans	-85	-52.6	-177.3	-52.3	0	0	0	0	112.8	G420 L421 V422	G420-T424 PolarHBondContact O-N 3.3Å; G420-T424 PolarHBondContact O-OG1 2.68Å; L421-T424 PolarHBondContact O-N 2.93Å; L421-T424 VanDerWaalsContact O-N 3.14Å; V422-T424 VanDerWaalsContact C-N 3.29Å; V422-T424 PolarHBondContact O-N 2.87Å
425	I	92.5	Very high	89.4	Confident	63 Å²	63	50.9 Å²	50.9	32%	0.323	29%	0.294	S	S	.	.	H	α-helix	trans	-106.9	3.9	-172.4	65.1	171.5	0	0	0	113.6	L421 G429 V433	L421-I425 HydrophobicContact CD1-CD1 3.57Å; L421-I425 HydrophobicContact CD1-CG1 3.83Å; L421-I425 HydrophobicContact CD2-CD1 4.23Å; L421-I425 HydrophobicContact CG-CD1 3.66Å; L421-I425 HydrophobicContact CG-CG1 3.87Å; L421-I425 WeakPolarHBondContact O-CG1 3.43Å; L421-I425 PolarHBondContact O-N 3.11Å; I425-G429 WeakPolarHBondContact O-CA 3.35Å; I425-G429 PolarHBondContact O-N 3.34Å; I425-V433 HydrophobicContact CD1-CG2 3.81Å
426	K	92.7	Very high	90.1	Very high	156 Å²	156	55.3 Å²	55.3	68%	0.678	32%	0.315	S	S	*	.	H	α-helix	trans	63.3	168.2	-173.9	-54.1	179.1	-179.2	176.7	0	112.2	V422 I428 G429 L430	V422-K426 WeakPolarHBondContact O-CA 3.38Å; V422-K426 PolarHBondContact O-N 3.39Å; K426-I428 PolarHBondContact O-N 2.92Å; K426-G429 PolarHBondContact O-N 2.89Å; K426-L430 PolarHBondContact O-N 3.29Å
427	F	92.4	Very high	90.7	Very high	11 Å²	11	53.8 Å²	53.8	5%	0.048	31%	0.307	C	S	.	.	H	α-helix	trans	-59.8	-34	179.4	-173.3	-102.6	0	0	0	113	L287 W294 I353 P354 L430 N431	L287-F427 HydrophobicContact CD1-CE2 4.22Å; L287-F427 HydrophobicContact CD1-CZ 3.91Å; W294-F427 HydrophobicContact CB-CD1 4.19Å; W294-F427 HydrophobicContact CB-CD2 3.86Å; W294-F427 HydrophobicContact CB-CE1 4.31Å; W294-F427 HydrophobicContact CB-CE2 4.03Å; W294-F427 HydrophobicContact CB-CG 3.95Å; W294-F427 HydrophobicContact CB-CZ 4.24Å; W294-F427 AromaticContact CD1-CD1 3.34Å; W294-F427 AromaticContact CD1-CG 3.49Å; W294-F427 VanDerWaalsContact CD1-CG 3.49Å; W294-F427 AromaticContact CD2-CD1 3.56Å; W294-F427 HydrophobicContact CD2-CD1 3.56Å; W294-F427 AromaticContact CD2-CE1 3.39Å; W294-F427 HydrophobicContact CD2-CE1 3.39Å; W294-F427 HydrophobicContact CD2-CG 4.23Å; W294-F427 AromaticContact CD2-CZ 3.97Å; W294-F427 HydrophobicContact CD2-CZ 3.97Å; W294-F427 AromaticContact CE2-CD1 3.55Å; W294-F427 AromaticContact CE2-CE1 3.65Å; W294-F427 HydrophobicContact CE3-CD1 4.34Å; W294-F427 AromaticContact CE3-CE1 3.7Å; W294-F427 HydrophobicContact CE3-CE1 3.7Å; W294-F427 HydrophobicContact CE3-CZ 4.01Å; W294-F427 HydrophobicContact CG-CB 4.17Å; W294-F427 AromaticContact CG-CD1 3.44Å; W294-F427 HydrophobicContact CG-CD1 3.44Å; W294-F427 VanDerWaalsContact CG-CD1 3.44Å; W294-F427 HydrophobicContact CG-CD2 4.02Å; W294-F427 AromaticContact CG-CE1 3.67Å; W294-F427 HydrophobicContact CG-CE1 3.67Å; W294-F427 HydrophobicContact CG-CE2 4.24Å; W294-F427 AromaticContact CG-CG 3.61Å; W294-F427 HydrophobicContact CG-CG 3.61Å; W294-F427 HydrophobicContact CG-CZ 4.07Å; W294-F427 HydrophobicContact CH2-CE1 4.39Å; W294-F427 HydrophobicContact CZ2-CD1 4.31Å; W294-F427 HydrophobicContact CZ2-CE1 4.16Å; W294-F427 HydrophobicContact CZ3-CE1 4.18Å; W294-F427 AromaticContact NE1-CD1 3.4Å; I353-F427 HydrophobicContact CG2-CE1 3.83Å; I353-F427 HydrophobicContact CG2-CZ 3.83Å; P354-F427 HydrophobicContact CB-CD1 4.24Å; P354-F427 HydrophobicContact CB-CE1 4.4Å; F427-L430 PolarHBondContact O-N 3.16Å; F427-N431 WeakPolarHBondContact CD1-ND2 3.29Å; F427-N431 WeakPolarHBondContact CE1-ND2 3.47Å; F427-N431 VanDerWaalsContact CZ-ND2 3.34Å; F427-N431 WeakPolarHBondContact CZ-ND2 3.34Å; F427-N431 PolarHBondContact O-N 3.09Å; F427-N431 VanDerWaalsContact O-N 3.16Å; F427-N431 PolarHBondContact O-ND2 2.93Å
428	I	94.5	Very high	91.2	Very high	82 Å²	82	50.7 Å²	50.7	42%	0.421	29%	0.289	S	S	.	.	H	α-helix	trans	-64.2	-48.9	175.7	-57.1	177.6	0	0	0	110.5	P354 K426 L430 N431 I432	P354-I428 HydrophobicContact CB-CB 4.42Å; P354-I428 HydrophobicContact CB-CG1 4.02Å; K426-I428 PolarHBondContact O-N 2.92Å; I428-L430 VanDerWaalsContact C-N 3.32Å; I428-L430 PolarHBondContact O-N 3.38Å; I428-N431 PolarHBondContact O-N 3.26Å; I428-I432 HydrophobicContact CG2-CD1 3.88Å; I428-I432 HydrophobicContact CG2-CG1 4.48Å; I428-I432 WeakPolarHBondContact O-CG1 3.4Å; I428-I432 PolarHBondContact O-N 3.02Å
429	G	94.5	Very high	91.9	Very high	16 Å²	16	54.2 Å²	54.2	17%	0.165	31%	0.307	C	S	.	.	H	α-helix	trans	-60.7	-41.7	178.7	0	0	0	0	0	111.9	I425 K426 N431 I432 V433	I425-G429 WeakPolarHBondContact O-CA 3.35Å; I425-G429 PolarHBondContact O-N 3.34Å; K426-G429 PolarHBondContact O-N 2.89Å; G429-N431 PolarHBondContact O-N 3.01Å; G429-I432 PolarHBondContact O-N 3.12Å; G429-V433 WeakPolarHBondContact O-CG2 3.48Å; G429-V433 PolarHBondContact O-N 3.3Å
430	L	93.6	Very high	93	Very high	3 Å²	3	54.9 Å²	54.9	2%	0.016	31%	0.314	C	S	.	.	H	α-helix	trans	-55.5	-50.8	175.4	175.1	68.3	0	0	0	111.6	F286 T290 L421 V422 K426 F427 I428 I432 V433 M434	F286-L430 HydrophobicContact CD1-CD1 3.64Å; F286-L430 HydrophobicContact CE1-CD1 4.24Å; F286-L430 HydrophobicContact CG-CD1 4.46Å; T290-L430 HydrophobicContact CG2-CD2 4.02Å; L421-L430 HydrophobicContact CB-CD1 4.46Å; L421-L430 HydrophobicContact CD2-CD1 3.53Å; L421-L430 HydrophobicContact CG-CD1 4.1Å; V422-L430 HydrophobicContact CG2-CB 4.23Å; V422-L430 HydrophobicContact CG2-CD2 3.54Å; V422-L430 HydrophobicContact CG2-CG 4.42Å; K426-L430 PolarHBondContact O-N 3.29Å; F427-L430 PolarHBondContact O-N 3.16Å; I428-L430 VanDerWaalsContact C-N 3.32Å; I428-L430 PolarHBondContact O-N 3.38Å; L430-I432 VanDerWaalsContact C-N 3.34Å; L430-I432 PolarHBondContact O-N 2.82Å; L430-V433 PolarHBondContact O-N 3.18Å; L430-M434 HydrophobicContact CD1-CE 4.01Å; L430-M434 WeakPolarHBondContact O-CG 3.41Å; L430-M434 PolarHBondContact O-N 3.17Å
431	N	95.6	Very high	93.8	Very high	6 Å²	6	54.8 Å²	54.8	3%	0.032	30%	0.301	C	S	.	.	H	α-helix	trans	-66	-34.9	-179	-81.7	-83.3	0	0	0	112.4	C350 P354 F427 I428 G429 M434 T435	C350-N431 WeakPolarHBondContact O-CB 3.29Å; C350-N431 PolarHBondContact O-OD1 3.19Å; P354-N431 HydrophobicContact CB-CB 4.47Å; P354-N431 HydrophobicContact CG-CB 3.84Å; F427-N431 WeakPolarHBondContact CD1-ND2 3.29Å; F427-N431 WeakPolarHBondContact CE1-ND2 3.47Å; F427-N431 VanDerWaalsContact CZ-ND2 3.34Å; F427-N431 WeakPolarHBondContact CZ-ND2 3.34Å; F427-N431 PolarHBondContact O-N 3.09Å; F427-N431 VanDerWaalsContact O-N 3.16Å; F427-N431 PolarHBondContact O-ND2 2.93Å; I428-N431 PolarHBondContact O-N 3.26Å; G429-N431 PolarHBondContact O-N 3.01Å; N431-M434 PolarHBondContact O-N 3.03Å; N431-T435 WeakPolarHBondContact O-CB 3.18Å; N431-T435 PolarHBondContact O-N 3.27Å; N431-T435 PolarHBondContact O-OG1 2.72Å
432	I	96.1	Very high	94.5	Very high	70 Å²	70	54.5 Å²	54.5	36%	0.359	30%	0.301	S	S	.	.	H	α-helix	trans	-64.2	-44.4	172.5	-67.9	170	0	0	0	110.5	I428 G429 L430 M434 T435 L436	I428-I432 HydrophobicContact CG2-CD1 3.88Å; I428-I432 HydrophobicContact CG2-CG1 4.48Å; I428-I432 WeakPolarHBondContact O-CG1 3.4Å; I428-I432 PolarHBondContact O-N 3.02Å; G429-I432 PolarHBondContact O-N 3.12Å; L430-I432 VanDerWaalsContact C-N 3.34Å; L430-I432 PolarHBondContact O-N 2.82Å; I432-M434 PolarHBondContact O-N 3.26Å; I432-T435 WeakPolarHBondContact O-CB 3.4Å; I432-T435 PolarHBondContact O-N 2.92Å; I432-L436 HydrophobicContact CG2-CD1 4.19Å; I432-L436 HydrophobicContact CG2-CG 4.45Å; I432-L436 WeakPolarHBondContact O-CG 3.49Å; I432-L436 PolarHBondContact O-N 2.96Å
433	V	95.4	Very high	95	Very high	51 Å²	51	57.7 Å²	57.7	31%	0.309	32%	0.322	S	S	.	.	H	α-helix	trans	-60.9	-45.9	176.4	172.7	0	0	0	0	110.9	I425 G429 L430 T435 L436 I437	I425-V433 HydrophobicContact CD1-CG2 3.81Å; G429-V433 WeakPolarHBondContact O-CG2 3.48Å; G429-V433 PolarHBondContact O-N 3.3Å; L430-V433 PolarHBondContact O-N 3.18Å; V433-T435 VanDerWaalsContact C-N 3.32Å; V433-T435 PolarHBondContact O-N 2.98Å; V433-L436 PolarHBondContact O-N 3.37Å; V433-L436 VanDerWaalsContact O-N 3.16Å; V433-I437 HydrophobicContact CG1-CD1 3.76Å; V433-I437 HydrophobicContact CG1-CG1 4.38Å; V433-I437 WeakPolarHBondContact O-CG1 3.28Å; V433-I437 PolarHBondContact O-N 3.04Å
434	M	95.1	Very high	95.6	Very high	9 Å²	9	53.5 Å²	53.5	4%	0.044	30%	0.301	C	S	.	.	H	α-helix	trans	-62.2	-38.7	176.4	-66	-54.9	123.5	0	0	112.4	V282 F286 C350 L430 N431 I432 L436 I437 T438	V282-M434 HydrophobicContact CG1-SD 4.02Å; F286-M434 HydrophobicContact CB-SD 4.46Å; F286-M434 HydrophobicContact CD1-CE 4.08Å; F286-M434 HydrophobicContact CD2-CE 4.31Å; F286-M434 HydrophobicContact CD2-SD 4.29Å; F286-M434 HydrophobicContact CE1-CE 4.15Å; F286-M434 HydrophobicContact CE2-CE 4.38Å; F286-M434 HydrophobicContact CG-CE 4.13Å; F286-M434 HydrophobicContact CG-SD 4.27Å; F286-M434 HydrophobicContact CZ-CE 4.29Å; C350-M434 HydrophobicContact CB-CB 4.43Å; L430-M434 HydrophobicContact CD1-CE 4.01Å; L430-M434 WeakPolarHBondContact O-CG 3.41Å; L430-M434 PolarHBondContact O-N 3.17Å; N431-M434 PolarHBondContact O-N 3.03Å; I432-M434 PolarHBondContact O-N 3.26Å; M434-L436 PolarHBondContact O-N 3.39Å; M434-I437 HydrophobicContact CE-CD1 4.08Å; M434-I437 PolarHBondContact O-N 3.5Å; M434-I437 HydrophobicContact SD-CD1 4.47Å; M434-T438 WeakPolarHBondContact O-CB 3.33Å; M434-T438 WeakPolarHBondContact O-CG2 3.32Å; M434-T438 PolarHBondContact O-N 3.24Å; M434-T438 PolarHBondContact O-OG1 3.46Å
435	T	97.8	Very high	95.9	Very high	13 Å²	13	48 Å²	48	8%	0.08	27%	0.268	C	S	.	.	H	α-helix	trans	-59.8	-45.4	172.6	-57.6	0	0	0	0	111.5	G347 C350 F351 N431 I432 V433 T438 L439	G347-T435 WeakPolarHBondContact O-CG2 3.46Å; G347-T435 PolarHBondContact O-OG1 3.06Å; C350-T435 WeakPolarHBondContact CB-OG1 3.43Å; F351-T435 WeakPolarHBondContact CA-OG1 3.29Å; F351-T435 HydrophobicContact CB-CG2 4.01Å; F351-T435 PolarHBondContact N-OG1 3.32Å; F351-T435 VanDerWaalsContact N-OG1 3.09Å; N431-T435 WeakPolarHBondContact O-CB 3.18Å; N431-T435 PolarHBondContact O-N 3.27Å; N431-T435 PolarHBondContact O-OG1 2.72Å; I432-T435 WeakPolarHBondContact O-CB 3.4Å; I432-T435 PolarHBondContact O-N 2.92Å; V433-T435 VanDerWaalsContact C-N 3.32Å; V433-T435 PolarHBondContact O-N 2.98Å; T435-T438 PolarHBondContact O-OG1 2.81Å; T435-T438 VanDerWaalsContact O-OG1 3.07Å; T435-L439 HydrophobicContact CG2-CD1 3.74Å; T435-L439 HydrophobicContact CG2-CG 4.25Å; T435-L439 VanDerWaalsContact O-CB 3.28Å; T435-L439 WeakPolarHBondContact O-CB 3.49Å; T435-L439 VanDerWaalsContact O-CG 3.31Å; T435-L439 WeakPolarHBondContact O-CG 3.43Å; T435-L439 PolarHBondContact O-N 3.28Å
436	L	97.5	Very high	96.1	Very high	120 Å²	120	51 Å²	51	63%	0.628	28%	0.275	S	S	*	.	H	α-helix	trans	-67.4	-38.7	-180	-68.6	174.5	0	0	0	112.1	I432 V433 M434 G440	I432-L436 HydrophobicContact CG2-CD1 4.19Å; I432-L436 HydrophobicContact CG2-CG 4.45Å; I432-L436 WeakPolarHBondContact O-CG 3.49Å; I432-L436 PolarHBondContact O-N 2.96Å; V433-L436 PolarHBondContact O-N 3.37Å; V433-L436 VanDerWaalsContact O-N 3.16Å; M434-L436 PolarHBondContact O-N 3.39Å; L436-G440 VanDerWaalsContact O-CA 3.3Å; L436-G440 WeakPolarHBondContact O-CA 3.47Å; L436-G440 PolarHBondContact O-N 3.18Å
437	I	96.6	Very high	96.2	Very high	71 Å²	71	48.5 Å²	48.5	36%	0.364	27%	0.269	S	S	.	.	H	α-helix	trans	-65.7	-49.5	177.6	-69.3	169.6	0	0	0	110.6	V279 V433 M434 G440 Y441	V279-I437 HydrophobicContact CG1-CG2 4.08Å; V279-I437 HydrophobicContact CG2-CG2 4.16Å; V433-I437 HydrophobicContact CG1-CD1 3.76Å; V433-I437 HydrophobicContact CG1-CG1 4.38Å; V433-I437 WeakPolarHBondContact O-CG1 3.28Å; V433-I437 PolarHBondContact O-N 3.04Å; M434-I437 HydrophobicContact CE-CD1 4.08Å; M434-I437 PolarHBondContact O-N 3.5Å; M434-I437 HydrophobicContact SD-CD1 4.47Å; I437-G440 PolarHBondContact O-N 3.27Å; I437-Y441 PolarHBondContact O-N 3.12Å; I437-Y441 VanDerWaalsContact O-N 3.16Å
438	T	97.4	Very high	96.3	Very high	0 Å²	0	48 Å²	48	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-66.2	-51.9	-178.1	48.5	0	0	0	0	111.9	V279 S283 E346 G347 M434 T435 G440 Y441 V442	V279-T438 HydrophobicContact CG1-CG2 3.97Å; S283-T438 WeakPolarHBondContact OG-CG2 3.37Å; E346-T438 VanDerWaalsContact OE1-CG2 3.31Å; E346-T438 WeakPolarHBondContact OE1-CG2 3.31Å; G347-T438 WeakPolarHBondContact CA-OG1 3.42Å; M434-T438 WeakPolarHBondContact O-CB 3.33Å; M434-T438 WeakPolarHBondContact O-CG2 3.32Å; M434-T438 PolarHBondContact O-N 3.24Å; M434-T438 PolarHBondContact O-OG1 3.46Å; T435-T438 PolarHBondContact O-OG1 2.81Å; T435-T438 VanDerWaalsContact O-OG1 3.07Å; T438-G440 VanDerWaalsContact C-N 3.31Å; T438-G440 PolarHBondContact O-N 2.96Å; T438-Y441 PolarHBondContact O-N 3.15Å; T438-V442 PolarHBondContact O-N 3.07Å
439	L	97.6	Very high	96.2	Very high	74 Å²	74	48.8 Å²	48.8	39%	0.387	26%	0.264	S	S	.	.	H	α-helix	trans	-65.7	-34.3	177	-64.7	-176	0	0	0	112.3	A344 T435 Y441 V442 P443	A344-L439 HydrophobicContact CB-CD2 4.39Å; T435-L439 HydrophobicContact CG2-CD1 3.74Å; T435-L439 HydrophobicContact CG2-CG 4.25Å; T435-L439 VanDerWaalsContact O-CB 3.28Å; T435-L439 WeakPolarHBondContact O-CB 3.49Å; T435-L439 VanDerWaalsContact O-CG 3.31Å; T435-L439 WeakPolarHBondContact O-CG 3.43Å; T435-L439 PolarHBondContact O-N 3.28Å; L439-Y441 PolarHBondContact O-N 2.87Å; L439-V442 WeakPolarHBondContact O-CB 3.36Å; L439-V442 PolarHBondContact O-N 3.06Å; L439-P443 WeakPolarHBondContact O-CD 3.29Å
440	G	97.4	Very high	95.8	Very high	50 Å²	50	51.5 Å²	51.5	52%	0.515	28%	0.275	S	S	.	.	H	α-helix	trans	-64.8	-24.5	176.3	0	0	0	0	0	113.5	L436 I437 T438 P443	L436-G440 VanDerWaalsContact O-CA 3.3Å; L436-G440 WeakPolarHBondContact O-CA 3.47Å; L436-G440 PolarHBondContact O-N 3.18Å; I437-G440 PolarHBondContact O-N 3.27Å; T438-G440 VanDerWaalsContact C-N 3.31Å; T438-G440 PolarHBondContact O-N 2.96Å; G440-P443 WeakPolarHBondContact O-CD 3.25Å
441	Y	98	Very high	95.5	Very high	41 Å²	41	51.6 Å²	51.6	16%	0.161	28%	0.276	C	S	.	.	H	α-helix	trans	-85.7	-19.5	177.3	-153.7	-90.2	0	0	0	113.3	I272 G275 C276 V279 L343 I437 T438 L439 V444 M445	I272-Y441 WeakPolarHBondContact CA-OH 3.43Å; I272-Y441 HydrophobicContact CG2-CE1 4.46Å; I272-Y441 PolarHBondContact O-OH 2.65Å; G275-Y441 WeakPolarHBondContact CA-OH 3.29Å; C276-Y441 HydrophobicContact CB-CD1 4.38Å; C276-Y441 HydrophobicContact CB-CE1 3.74Å; C276-Y441 PolarHBondContact N-OH 2.72Å; V279-Y441 HydrophobicContact CB-CG 4.44Å; V279-Y441 HydrophobicContact CG1-CG 4.41Å; V279-Y441 HydrophobicContact CG2-CD2 3.86Å; V279-Y441 HydrophobicContact CG2-CE2 4.32Å; V279-Y441 HydrophobicContact CG2-CG 4.1Å; L343-Y441 HydrophobicContact CD1-CD1 3.92Å; I437-Y441 PolarHBondContact O-N 3.12Å; I437-Y441 VanDerWaalsContact O-N 3.16Å; T438-Y441 PolarHBondContact O-N 3.15Å; L439-Y441 PolarHBondContact O-N 2.87Å; Y441-V444 HydrophobicContact CD1-CB 4.29Å; Y441-V444 HydrophobicContact CD2-CG2 4.34Å; Y441-V444 HydrophobicContact CE1-CB 4.27Å; Y441-V444 HydrophobicContact CE1-CG1 4.31Å; Y441-V444 HydrophobicContact CE2-CG1 4.42Å; Y441-V444 HydrophobicContact CG-CB 4.44Å; Y441-V444 HydrophobicContact CG-CG2 4.48Å; Y441-V444 VanDerWaalsContact O-CB 3.25Å; Y441-V444 WeakPolarHBondContact O-CB 3.19Å; Y441-V444 PolarHBondContact O-N 2.94Å; Y441-M445 HydrophobicContact CD1-CG 4.44Å; Y441-M445 HydrophobicContact CD1-SD 4.1Å; Y441-M445 HydrophobicContact CE1-SD 3.85Å; Y441-M445 PolarHBondContact O-N 2.67Å
442	V	98.2	Very high	94.9	Very high	37 Å²	37	52.7 Å²	52.7	22%	0.224	28%	0.28	C	S	.	.	H	α-helix	trans	-53.7	-45.9	179.8	175.3	0	0	0	0	112.9	A340 L343 A344 T438 L439 V444 M445	A340-V442 HydrophobicContact CB-CG1 4.27Å; L343-V442 HydrophobicContact CB-CG2 3.75Å; A344-V442 HydrophobicContact CB-CG2 4.18Å; T438-V442 PolarHBondContact O-N 3.07Å; L439-V442 WeakPolarHBondContact O-CB 3.36Å; L439-V442 PolarHBondContact O-N 3.06Å; V442-V444 VanDerWaalsContact C-N 3.25Å; V442-V444 PolarHBondContact O-N 3.15Å; V442-M445 WeakPolarHBondContact O-CB 3.48Å; V442-M445 PolarHBondContact O-N 2.79Å
443	P	97.6	Very high	94	Very high	90 Å²	90	54.8 Å²	54.8	58%	0.584	29%	0.292	S	S	*	.	H	α-helix	trans	-63	-29.2	176.6	-22.6	34.6	0	0	0	113.6	L439 G440 M445 Y446	L439-P443 WeakPolarHBondContact O-CD 3.29Å; G440-P443 WeakPolarHBondContact O-CD 3.25Å; P443-M445 PolarHBondContact O-N 3.26Å; P443-Y446 WeakPolarHBondContact O-CB 3.29Å; P443-Y446 PolarHBondContact O-N 3.06Å; P443-Y446 VanDerWaalsContact O-N 3.16Å
444	V	97.4	Very high	92.8	Very high	46 Å²	46	56.2 Å²	56.2	28%	0.279	30%	0.301	S	S	.	.	H	α-helix	trans	-64.3	-33.9	178.4	-173.7	0	0	0	0	110.6	I272 Y441 V442 Y446 L447	I272-V444 HydrophobicContact CG1-CG1 4.12Å; I272-V444 HydrophobicContact CG2-CG1 4.05Å; Y441-V444 HydrophobicContact CD1-CB 4.29Å; Y441-V444 HydrophobicContact CD2-CG2 4.34Å; Y441-V444 HydrophobicContact CE1-CB 4.27Å; Y441-V444 HydrophobicContact CE1-CG1 4.31Å; Y441-V444 HydrophobicContact CE2-CG1 4.42Å; Y441-V444 HydrophobicContact CG-CB 4.44Å; Y441-V444 HydrophobicContact CG-CG2 4.48Å; Y441-V444 VanDerWaalsContact O-CB 3.25Å; Y441-V444 WeakPolarHBondContact O-CB 3.19Å; Y441-V444 PolarHBondContact O-N 2.94Å; V442-V444 VanDerWaalsContact C-N 3.25Å; V442-V444 PolarHBondContact O-N 3.15Å; V444-Y446 PolarHBondContact O-N 2.74Å; V444-Y446 VanDerWaalsContact O-N 3.12Å; V444-L447 HydrophobicContact CG1-CD1 4.23Å; V444-L447 VanDerWaalsContact O-CB 3.29Å; V444-L447 WeakPolarHBondContact O-CB 3.5Å; V444-L447 WeakPolarHBondContact O-CG 3.42Å; V444-L447 PolarHBondContact O-N 3.5Å
445	M	97.1	Very high	91.1	Very high	0 Å²	0	64.1 Å²	64.1	0%	0	34%	0.338	C	S	.	.	H	α-helix	trans	-60	-24.7	176.8	-62.4	-52.1	-63.6	0	0	113.4	I272 C276 A339 A340 L343 I380 Y441 V442 P443 L447 L448	I272-M445 HydrophobicContact CG2-SD 4.24Å; C276-M445 HydrophobicContact CB-CE 4.32Å; C276-M445 HydrophobicContact CB-SD 3.78Å; A339-M445 HydrophobicContact CB-CE 3.8Å; A340-M445 HydrophobicContact CB-CB 3.81Å; A340-M445 HydrophobicContact CB-CG 4.19Å; L343-M445 HydrophobicContact CD1-CG 3.92Å; L343-M445 HydrophobicContact CD1-SD 4.36Å; I380-M445 HydrophobicContact CD1-CE 3.6Å; Y441-M445 HydrophobicContact CD1-CG 4.44Å; Y441-M445 HydrophobicContact CD1-SD 4.1Å; Y441-M445 HydrophobicContact CE1-SD 3.85Å; Y441-M445 PolarHBondContact O-N 2.67Å; V442-M445 WeakPolarHBondContact O-CB 3.48Å; V442-M445 PolarHBondContact O-N 2.79Å; P443-M445 PolarHBondContact O-N 3.26Å; M445-L447 PolarHBondContact O-N 2.94Å; M445-L448 HydrophobicContact CE-CD1 3.67Å; M445-L448 WeakPolarHBondContact O-CB 3.22Å; M445-L448 PolarHBondContact O-N 3.33Å; M445-L448 VanDerWaalsContact O-N 3.09Å; M445-L448 HydrophobicContact SD-CD1 4.46Å
446	Y	95.2	Very high	89.2	Confident	124 Å²	124	66.9 Å²	66.9	49%	0.486	35%	0.347	S	S	.	.	G	3₁₀ helix	trans	-62.5	-25.9	175.5	-172.4	-115.9	0	0	0	113.2	W336 P443 V444 L448 R449	W336-Y446 AromaticContact CH2-CD2 3.85Å; W336-Y446 HydrophobicContact CH2-CD2 3.85Å; W336-Y446 HydrophobicContact CH2-CE2 4.38Å; W336-Y446 HydrophobicContact CZ3-CD2 4.02Å; P443-Y446 WeakPolarHBondContact O-CB 3.29Å; P443-Y446 PolarHBondContact O-N 3.06Å; P443-Y446 VanDerWaalsContact O-N 3.16Å; V444-Y446 PolarHBondContact O-N 2.74Å; V444-Y446 VanDerWaalsContact O-N 3.12Å; Y446-L448 PolarHBondContact O-N 3.04Å; Y446-R449 HydrophobicContact CD2-CB 4.5Å; Y446-R449 VanDerWaalsContact O-CB 3.23Å; Y446-R449 WeakPolarHBondContact O-CB 3.23Å; Y446-R449 VanDerWaalsContact O-CG 3.22Å; Y446-R449 WeakPolarHBondContact O-CG 3.37Å; Y446-R449 PolarHBondContact O-N 3.28Å; Y446-R449 PolarHBondContact OH-NH1 2.91Å
447	L	95.3	Very high	87.1	Confident	104 Å²	104	66.1 Å²	66.1	55%	0.545	35%	0.348	S	S	.	.	G	3₁₀ helix	trans	-65.5	-22	176.6	-60.1	177.3	0	0	0	112.3	Y269 I272 V444 M445 R449	Y269-L447 WeakPolarHBondContact CE1-O 3.43Å; I272-L447 HydrophobicContact CD1-CB 3.84Å; I272-L447 HydrophobicContact CD1-CD1 3.96Å; V444-L447 HydrophobicContact CG1-CD1 4.23Å; V444-L447 VanDerWaalsContact O-CB 3.29Å; V444-L447 WeakPolarHBondContact O-CB 3.5Å; V444-L447 WeakPolarHBondContact O-CG 3.42Å; V444-L447 PolarHBondContact O-N 3.5Å; M445-L447 PolarHBondContact O-N 2.94Å; L447-R449 VanDerWaalsContact C-N 3.32Å
448	L	94.3	Very high	84.8	Confident	0 Å²	0	71.6 Å²	71.6	0%	0	37%	0.372	C	S	.	.	G	3₁₀ helix	trans	-82.4	-3.5	174.7	-66.3	175.6	0	0	0	113.4	Y269 I272 W336 M445 Y446 N450 C451	Y269-L448 HydrophobicContact CD1-CD2 3.68Å; Y269-L448 HydrophobicContact CG-CD2 3.79Å; I272-L448 HydrophobicContact CB-CD2 4.4Å; I272-L448 HydrophobicContact CB-CG 4.44Å; I272-L448 HydrophobicContact CG2-CD1 3.77Å; I272-L448 HydrophobicContact CG2-CD2 4.37Å; I272-L448 HydrophobicContact CG2-CG 3.88Å; W336-L448 HydrophobicContact CB-CB 3.76Å; W336-L448 HydrophobicContact CG-CB 4.48Å; M445-L448 HydrophobicContact CE-CD1 3.67Å; M445-L448 WeakPolarHBondContact O-CB 3.22Å; M445-L448 PolarHBondContact O-N 3.33Å; M445-L448 VanDerWaalsContact O-N 3.09Å; M445-L448 HydrophobicContact SD-CD1 4.46Å; Y446-L448 PolarHBondContact O-N 3.04Å; L448-N450 PolarHBondContact O-N 3.47Å; L448-C451 PolarHBondContact O-N 2.82Å; L448-C451 PolarHBondContact O-SG 3.32Å
449	R	91.7	Very high	82.1	Confident	99 Å²	99	78.5 Å²	78.5	37%	0.374	41%	0.41	S	S	.	.	T	Hydrogen-bonded Turn	trans	-55.6	-27.4	-173.1	74.8	-174.5	-175.5	-163.4	-11.8	115.2	W336 Y446 L447	W336-R449 HydrophobicContact CD2-CB 4.23Å; W336-R449 HydrophobicContact CH2-CB 4.33Å; W336-R449 HydrophobicContact CZ2-CB 3.75Å; Y446-R449 HydrophobicContact CD2-CB 4.5Å; Y446-R449 VanDerWaalsContact O-CB 3.23Å; Y446-R449 WeakPolarHBondContact O-CB 3.23Å; Y446-R449 VanDerWaalsContact O-CG 3.22Å; Y446-R449 WeakPolarHBondContact O-CG 3.37Å; Y446-R449 PolarHBondContact O-N 3.28Å; Y446-R449 PolarHBondContact OH-NH1 2.91Å; L447-R449 VanDerWaalsContact C-N 3.32Å
450	N	87.4	Confident	79.5	Confident	74 Å²	74	83 Å²	83	40%	0.396	42%	0.421	S	S	.	.	T	Hydrogen-bonded Turn	trans	-102.3	0.4	-174.9	-72.8	-16.9	0	0	0	112.9	L448 Y452 N453	L448-N450 PolarHBondContact O-N 3.47Å; N450-Y452 VanDerWaalsContact C-N 3.3Å; N450-Y452 PolarHBondContact O-N 3.43Å; N450-N453 WeakPolarHBondContact O-CB 3.35Å; N450-N453 PolarHBondContact O-N 3.31Å; N450-N453 PolarHBondContact OD1-ND2 2.81Å
451	C	86.5	Confident	76.6	Confident	4 Å²	4	89.2 Å²	89.2	3%	0.027	44%	0.437	C	S	.	.	G	3₁₀ helix	trans	-64.1	-37.7	-175.5	66.7	0	0	0	0	111.9	Y269 F386 L387 L448 N453	Y269-C451 HydrophobicContact CD2-CB 4.13Å; Y269-C451 HydrophobicContact CE2-CB 4.34Å; F386-C451 WeakPolarHBondContact CE1-O 3.44Å; L387-C451 HydrophobicContact CD2-CB 3.89Å; L448-C451 PolarHBondContact O-N 2.82Å; L448-C451 PolarHBondContact O-SG 3.32Å; C451-N453 VanDerWaalsContact C-N 3.28Å; C451-N453 PolarHBondContact O-N 3.26Å
452	Y	84.3	Confident	73.8	Confident	29 Å²	29	91.5 Å²	91.5	11%	0.114	45%	0.451	C	S	.	.	G	3₁₀ helix	trans	-78.7	-0.1	179	-77.2	-83.3	0	0	0	115.1	E183 Q335 T383 F386 N450 V454	E183-Y452 HydrophobicContact CG-CE1 4.42Å; E183-Y452 PolarHBondContact OE1-OH 3.3Å; E183-Y452 VanDerWaalsContact OE1-OH 3.06Å; Q335-Y452 HydrophobicContact CB-CE2 4.11Å; Q335-Y452 PolarHBondContact NE2-OH 2.8Å; Q335-Y452 PolarHBondContact OE1-OH 3.48Å; T383-Y452 WeakPolarHBondContact CA-OH 3.42Å; T383-Y452 HydrophobicContact CG2-CE2 4.16Å; T383-Y452 PolarHBondContact OG1-OH 2.87Å; T383-Y452 VanDerWaalsContact OG1-OH 3.06Å; F386-Y452 HydrophobicContact CB-CE1 4.37Å; F386-Y452 HydrophobicContact CD1-CD1 4.11Å; F386-Y452 AromaticContact CD1-CE1 3.94Å; F386-Y452 HydrophobicContact CD1-CE1 3.94Å; F386-Y452 HydrophobicContact CD2-CD1 4.18Å; F386-Y452 AromaticContact CD2-CE1 3.86Å; F386-Y452 HydrophobicContact CD2-CE1 3.86Å; F386-Y452 AromaticContact CE1-CD1 3.89Å; F386-Y452 HydrophobicContact CE1-CD1 3.89Å; F386-Y452 HydrophobicContact CE1-CE1 4.2Å; F386-Y452 HydrophobicContact CE1-CG 4.27Å; F386-Y452 AromaticContact CE2-CD1 3.97Å; F386-Y452 HydrophobicContact CE2-CD1 3.97Å; F386-Y452 HydrophobicContact CE2-CE1 4.13Å; F386-Y452 HydrophobicContact CG-CD1 4.26Å; F386-Y452 AromaticContact CG-CE1 3.78Å; F386-Y452 HydrophobicContact CG-CE1 3.78Å; F386-Y452 AromaticContact CZ-CD1 3.81Å; F386-Y452 HydrophobicContact CZ-CD1 3.81Å; F386-Y452 HydrophobicContact CZ-CE1 4.29Å; F386-Y452 HydrophobicContact CZ-CG 4.46Å; N450-Y452 VanDerWaalsContact C-N 3.3Å; N450-Y452 PolarHBondContact O-N 3.43Å; Y452-V454 PolarHBondContact O-N 2.67Å
453	N	76.7	Confident	70.8	Confident	114 Å²	114	95 Å²	95	61%	0.61	47%	0.474	S	S	*	.	G	3₁₀ helix	trans	-77.6	-10.7	177.9	-66.5	-10.5	0	0	0	112.7	N450 C451	N450-N453 WeakPolarHBondContact O-CB 3.35Å; N450-N453 PolarHBondContact O-N 3.31Å; N450-N453 PolarHBondContact OD1-ND2 2.81Å; C451-N453 VanDerWaalsContact C-N 3.28Å; C451-N453 PolarHBondContact O-N 3.26Å
454	V	70.4	Confident	67.7	Low	82 Å²	82	94.4 Å²	94.4	50%	0.497	47%	0.473	S	S	.	.	S	Bend	trans	-90.4	113.4	178.7	-176	0	0	0	0	108.2	T390 Y452	T390-V454 HydrophobicContact CG2-CG1 4.49Å; Y452-V454 PolarHBondContact O-N 2.67Å
455	E	59.4	Low	64.6	Low	175 Å²	175	97.2 Å²	97.2	82%	0.818	49%	0.485	S	S	*	.	P	Polyproline II helix	trans	-64.2	139.3	172	-72.9	-178	174.4	0	0	110.4
456	R	56.3	Low	61.3	Low	71 Å²	71	104.5 Å²	104.5	27%	0.268	52%	0.517	S	S	.	.	P	Polyproline II helix	trans	-67.2	142	172.1	-69.4	-174.8	-175.6	-175.8	6.2	109.4	T181 E183 F386 D389 T390 Q458	T181-R456 PolarHBondContact O-NH1 3.18Å; E183-R456 IonicContact OE2-CZ 3.89Å; E183-R456 IonicContact OE2-NH2 2.72Å; E183-R456 PolarHBondContact OE2-NH2 3.28Å; F386-R456 HydrophobicContact CE2-CG 4.08Å; D389-R456 IonicContact OD2-CZ 3.66Å; D389-R456 IonicContact OD2-NE 3.7Å; D389-R456 IonicContact OD2-NH1 3.56Å; D389-R456 IonicContact OD2-NH2 3.59Å; T390-R456 HydrophobicContact CG2-CG 4Å; R456-Q458 PolarHBondContact O-N 3.5Å; R456-Q458 VanDerWaalsContact O-N 3.13Å
457	P	55.3	Low	58.4	Low	103 Å²	103	103.8 Å²	103.8	67%	0.669	53%	0.526	S	S	*	.	P	Polyproline II helix	trans	-58.6	120	166.1	-14.2	26.5	0	0	0	108.8	N459	P457-N459 PolarHBondContact O-N 3.4Å
458	Q	48.2	Very low	55.5	Low	186 Å²	186	105.4 Å²	105.4	87%	0.869	54%	0.535	S	S	*	.	S	Bend	trans	-65.2	-5.2	-176.8	-74.3	-174.9	-16.9	0	0	114.4	R456 R460	R456-Q458 PolarHBondContact O-N 3.5Å; R456-Q458 VanDerWaalsContact O-N 3.13Å; Q458-R460 PolarHBondContact O-N 2.84Å
459	N	40.5	Very low	52.5	Low	146 Å²	146	109.7 Å²	109.7	78%	0.781	57%	0.565	S	S	*	*			trans	-95.8	76.4	-173.8	-70	-12.1	0	0	0	112	P457	P457-N459 PolarHBondContact O-N 3.4Å
460	R	41.5	Very low	49.5	Very low	167 Å²	167	109 Å²	109	63%	0.63	57%	0.568	S	S	*	*			trans	-172	48.6	158.4	-107.5	173.7	-154.9	-165	6.7	112.9	Q458 I462	Q458-R460 PolarHBondContact O-N 2.84Å; R460-I462 VanDerWaalsContact C-N 3.29Å; R460-I462 PolarHBondContact O-N 3.24Å; R460-I462 VanDerWaalsContact O-N 3.15Å
461	E	36.7	Very low	46.7	Very low	181 Å²	181	111.2 Å²	111.2	85%	0.846	58%	0.579	S	S	*	*			trans	-66.6	106.5	139.6	-72.4	-175.4	178.5	0	0	104.6	P463	E461-P463 WeakPolarHBondContact O-CD 3.43Å
462	I	40.7	Very low	43.9	Very low	89 Å²	89	119.3 Å²	119.3	46%	0.456	62%	0.617	S	S	.	*			trans	-55.9	117.1	165	-58.3	165.5	0	0	0	103.4	E245 R460 S464	E245-I462 VanDerWaalsContact OE1-CG2 3.31Å; E245-I462 WeakPolarHBondContact OE1-CG2 3.31Å; R460-I462 VanDerWaalsContact C-N 3.29Å; R460-I462 PolarHBondContact O-N 3.24Å; R460-I462 VanDerWaalsContact O-N 3.15Å; I462-S464 PolarHBondContact O-N 3.23Å
463	P	33.4	Very low	41.2	Very low	110 Å²	110	121.8 Å²	121.8	71%	0.714	64%	0.638	S	S	*	*			trans	-56.4	112.3	174.8	-18.4	30.3	0	0	0	104.4	E461 L465	E461-P463 WeakPolarHBondContact O-CD 3.43Å; P463-L465 PolarHBondContact O-N 2.96Å
464	S	34.3	Very low	38.8	Very low	78 Å²	78	124.5 Å²	124.5	55%	0.545	65%	0.645	S	S	.	*			trans	-49	119.4	163	43.7	0	0	0	0	103.7	I462 K466	I462-S464 PolarHBondContact O-N 3.23Å; S464-K466 PolarHBondContact O-N 3.38Å
465	L	30.3	Very low	36.9	Very low	105 Å²	105	127.3 Å²	127.3	55%	0.55	66%	0.657	S	S	.	*			trans	-52.2	100.1	168.5	-87.2	156.3	0	0	0	103.9	P463 T467	P463-L465 PolarHBondContact O-N 2.96Å; L465-T467 PolarHBondContact O-N 3.06Å
466	K	28.7	Very low	35.4	Very low	154 Å²	154	127.8 Å²	127.8	67%	0.67	66%	0.659	S	S	*	*			trans	-56.2	113.9	169.1	-78.5	-174.6	175.3	-175.5	0	102.6	S464 D468 S469	S464-K466 PolarHBondContact O-N 3.38Å; K466-D468 PolarHBondContact O-N 3.06Å; K466-S469 PolarHBondContact O-N 3.02Å; K466-S469 PolarHBondContact O-OG 3.3Å
467	T	34.3	Very low	34.2	Very low	108 Å²	108	131.2 Å²	131.2	66%	0.663	68%	0.683	S	S	*	*	G	3₁₀ helix	trans	-57.8	-0.5	176.9	23.2	0	0	0	0	112.9	L465 S469 I470	L465-T467 PolarHBondContact O-N 3.06Å; T467-S469 PolarHBondContact O-N 3.34Å; T467-I470 HydrophobicContact CG2-CD1 4.38Å
468	D	34.7	Very low	32.9	Very low	139 Å²	139	133.7 Å²	133.7	74%	0.743	69%	0.691	S	S	*	*	G	3₁₀ helix	trans	-71.4	-11.9	171.7	-56.3	-22.2	0	0	0	113.7	K466	K466-D468 PolarHBondContact O-N 3.06Å
469	S	30.8	Very low	31.8	Very low	89 Å²	89	136.2 Å²	136.2	62%	0.622	69%	0.694	S	S	*	*	G	3₁₀ helix	trans	-115.4	11.1	174.9	62.7	0	0	0	0	114.9	K466 T467 D471	K466-S469 PolarHBondContact O-N 3.02Å; K466-S469 PolarHBondContact O-OG 3.3Å; T467-S469 PolarHBondContact O-N 3.34Å; S469-D471 PolarHBondContact O-N 3Å
470	I	28.4	Very low	31.3	Very low	85 Å²	85	132.8 Å²	132.8	44%	0.436	69%	0.685	S	S	.	*	S	Bend	trans	-87.9	82.1	155.7	-55.2	176.9	0	0	0	104.7	T467 H472	T467-I470 HydrophobicContact CG2-CD1 4.38Å; I470-H472 PolarHBondContact O-N 3.29Å
471	D	28.6	Very low	30.6	Very low	120 Å²	120	130.5 Å²	130.5	64%	0.642	69%	0.692	S	S	*	*			trans	-48.8	118.8	167.1	-82.2	-38.7	0	0	0	107.3	S469 S473	S469-D471 PolarHBondContact O-N 3Å; D471-S473 WeakPolarHBondContact CB-OG 3.21Å; D471-S473 PolarHBondContact O-N 3.21Å
472	H	29.2	Very low	30	Very low	175 Å²	175	129.7 Å²	129.7	81%	0.81	69%	0.692	S	S	*	*			trans	-70	22.2	173.2	-92.6	-68.7	0	0	0	112.3	I470 F474	I470-H472 PolarHBondContact O-N 3.29Å; H472-F474 PolarHBondContact O-N 3.01Å
473	S	27.5	Very low	29.4	Very low	81 Å²	81	134.8 Å²	134.8	57%	0.566	71%	0.711	S	S	*	*			trans	-76.6	54.9	164.1	53.2	0	0	0	0	110.8	D471 D475	D471-S473 WeakPolarHBondContact CB-OG 3.21Å; D471-S473 PolarHBondContact O-N 3.21Å; S473-D475 PolarHBondContact O-N 2.78Å; S473-D475 VanDerWaalsContact O-N 3.16Å
474	F	25.6	Very low	29	Very low	171 Å²	171	136.4 Å²	136.4	75%	0.75	71%	0.714	S	S	*	*			trans	-79	72.9	144.9	-75	-84.2	0	0	0	106.1	H472 Q476	H472-F474 PolarHBondContact O-N 3.01Å; F474-Q476 PolarHBondContact O-N 3.27Å
475	D	29.8	Very low	28.4	Very low	140 Å²	140	144 Å²	144	75%	0.749	73%	0.732	S	S	*	*			trans	-56.3	128.9	164	-82.7	-37.4	0	0	0	107.3	S473 D477	S473-D475 PolarHBondContact O-N 2.78Å; S473-D475 VanDerWaalsContact O-N 3.16Å; D475-D477 PolarHBondContact O-N 2.74Å
476	Q	28.9	Very low	28.1	Very low	185 Å²	185	144.8 Å²	144.8	86%	0.864	74%	0.743	S	S	*	*	S	Bend	trans	-69.1	9.7	-172.1	-100.5	177.7	-16.4	0	0	114.5	F474	F474-Q476 PolarHBondContact O-N 3.27Å
477	D	30.2	Very low	27.9	Very low	143 Å²	143	141 Å²	141	77%	0.765	75%	0.748	S	S	*	*			trans	-125.7	71.5	-171.4	-66.9	-34.3	0	0	0	111.3	D475	D475-D477 PolarHBondContact O-N 2.74Å
478	D	28.8	Very low	27.3	Very low	155 Å²	155	147.1 Å²	147.1	83%	0.829	76%	0.761	S	S	*	*			trans	-154.8	56.1	153.8	-102	-23.6	0	0	0	111.1	A480	D478-A480 PolarHBondContact O-N 3.31Å; D478-A480 VanDerWaalsContact O-N 3.17Å
479	Y	25.2	Very low	26.8	Very low	240 Å²	240	149.1 Å²	149.1	94%	0.941	77%	0.766	S	S	*	*			trans	-77.3	80.4	153.7	-84.6	-88.1	0	0	0	108.6
480	A	29.8	Very low	26.4	Very low	73 Å²	73	153.2 Å²	153.2	60%	0.603	78%	0.775	S	S	*	*			trans	-122.8	132.7	163.5	0	0	0	0	0	110.2	D478	D478-A480 PolarHBondContact O-N 3.31Å; D478-A480 VanDerWaalsContact O-N 3.17Å
481	P	27.2	Very low	26	Very low	119 Å²	119	156.6 Å²	156.6	77%	0.773	79%	0.794	S	S	*	*			trans	-79.6	143	-156.5	7.2	7.5	0	0	0	112.3	K483	P481-K483 PolarHBondContact O-N 3.42Å
482	I	24.2	Very low	25.8	Very low	164 Å²	164	155.8 Å²	155.8	84%	0.841	80%	0.798	S	S	*	*			trans	-43.3	100.7	171.5	-54.8	165.6	0	0	0	109.7
483	K	26.6	Very low	25.4	Very low	196 Å²	196	153.9 Å²	153.9	85%	0.852	80%	0.799	S	S	*	*			trans	-96.1	120.2	168.1	-89.6	-176	177.6	177.3	0	109.4	P481	P481-K483 PolarHBondContact O-N 3.42Å
484	N	25.7	Very low	25.3	Very low	145 Å²	145	157.6 Å²	157.6	78%	0.775	81%	0.811	S	S	*	*			trans	-34.6	131.5	176.7	-67.3	-31.3	0	0	0	114.8	P486	N484-P486 WeakPolarHBondContact O-CD 3.48Å
485	Y	21.1	Very low	25	Very low	236 Å²	236	159 Å²	159	93%	0.925	82%	0.816	S	S	*	*			trans	-64.8	131.7	165.8	-68.3	-92.8	0	0	0	111.4
486	P	25.1	Very low	24.7	Very low	122 Å²	122	155.4 Å²	155.4	79%	0.792	81%	0.813	S	S	*	*			trans	-124.3	132.8	151.9	28.1	-9.9	0	0	0	111.4	N484	N484-P486 WeakPolarHBondContact O-CD 3.48Å
487	G	25	Very low	24.5	Very low	75 Å²	75	155.4 Å²	155.4	77%	0.773	81%	0.812	S	S	*	*			trans	73.6	102.8	130.9	0	0	0	0	0	118.3	E489	G487-E489 PolarHBondContact O-N 3.13Å
488	Y	20.8	Very low	24.4	Very low	237 Å²	237	153.8 Å²	153.8	93%	0.929	81%	0.81	S	S	*	*			trans	-26.5	121.8	140.4	-91.3	-107.3	0	0	0	114.4
489	E	23.8	Very low	24.3	Very low	181 Å²	181	153.7 Å²	153.7	85%	0.846	81%	0.809	S	S	*	*			trans	-156.6	97	150.8	-105.2	170.6	-160.1	0	0	107.2	G487	G487-E489 PolarHBondContact O-N 3.13Å
490	Q	22.1	Very low	24.1	Very low	175 Å²	175	150.5 Å²	150.5	82%	0.818	80%	0.803	S	S	*	*				62.4	110.6	107.2	-85.1	-171.7	0.3	0	0	116.7
491	N	20.6	Very low	24	Very low	155 Å²	155	155.1 Å²	155.1	83%	0.829	81%	0.811	S	S	*	*			trans	47.8	102.9	138.2	-68	-12.6	0	0	0	119.2
492	S	24.5	Very low	23.9	Very low	104 Å²	104	155 Å²	155	73%	0.727	81%	0.81	S	S	*	*			trans	-151.6	108.8	137.7	58.6	0	0	0	0	111.6
493	T	21.6	Very low	24	Very low	135 Å²	135	158.9 Å²	158.9	83%	0.828	82%	0.815	S	S	*	*			trans	-12.7	120.1	149.5	-20.7	0	0	0	0	115.4
494	I	25.6	Very low	23.8	Very low	158 Å²	158	157.2 Å²	157.2	81%	0.81	81%	0.81	S	S	*	*			trans	-131.2	107.7	158	-58.1	-178.4	0	0	0	108.6
495	K	18.7	Very low	23.6	Very low	201 Å²	201	158.5 Å²	158.5	87%	0.874	81%	0.811	S	S	*	*			trans	-91.5	144.3	160.6	-87.8	180	170.5	179.4	0	108.1
496	G	22.9	Very low	23.7	Very low	65 Å²	65	156.5 Å²	156.5	67%	0.67	80%	0.804	S	S	*	*			trans	92.5	131.2	170.4	0	0	0	0	0	112.3
497	E	25.2	Very low	23.5	Very low	184 Å²	184	158.8 Å²	158.8	86%	0.86	80%	0.803	S	S	*	*			cis	-162.1	166	16.4	-99.4	177.9	156.8	0	0	108.6	N499	E497-N499 PolarHBondContact O-N 3.41Å
498	P	27.1	Very low	23.6	Very low	110 Å²	110	163.2 Å²	163.2	71%	0.714	80%	0.803	S	S	*	*			trans	-87.9	110.3	-169.5	33.1	-29.8	0	0	0	112.5	H500	P498-H500 PolarHBondContact O-N 3.22Å
499	N	27.2	Very low	23.8	Very low	152 Å²	152	157.4 Å²	157.4	81%	0.813	80%	0.795	S	S	*	*			trans	-78.9	103.3	168.8	-83.9	-27.7	0	0	0	111	E497 H501	E497-N499 PolarHBondContact O-N 3.41Å; N499-H501 PolarHBondContact O-N 3.46Å
500	H	22.4	Very low	23.9	Very low	173 Å²	173	158.5 Å²	158.5	80%	0.801	80%	0.797	S	S	*	*			trans	-67.4	108.4	158.1	-85.2	22.6	0	0	0	109.8	P498	P498-H500 PolarHBondContact O-N 3.22Å
501	H	27.1	Very low	24.1	Very low	170 Å²	170	158 Å²	158	79%	0.787	80%	0.8	S	S	*	*			trans	-128.2	126.5	152.4	-79.8	-50.3	0	0	0	109.9	N499	N499-H501 PolarHBondContact O-N 3.46Å
502	P	25.3	Very low	24.5	Very low	116 Å²	116	155.7 Å²	155.7	75%	0.753	79%	0.793	S	S	*	*			trans	-75.5	132.1	-172.2	28.3	-30.6	0	0	0	111.1	Q504	P502-Q504 PolarHBondContact O-N 3.37Å; P502-Q504 VanDerWaalsContact O-N 3.1Å
503	R	25.4	Very low	24.6	Very low	246 Å²	246	158.2 Å²	158.2	93%	0.928	80%	0.797	S	S	*	*			trans	-61.1	109.1	173	-76.2	-176.7	-176.3	-179.1	0.9	109.8	Q505	R503-Q505 PolarHBondContact O-N 3.1Å
504	Q	23.2	Very low	24.8	Very low	162 Å²	162	158.5 Å²	158.5	76%	0.757	79%	0.793	S	S	*	*			trans	-68.6	117.7	164	-71.3	-178.5	3.9	0	0	108.8	P502 Y506	P502-Q504 PolarHBondContact O-N 3.37Å; P502-Q504 VanDerWaalsContact O-N 3.1Å; Q504-Y506 PolarHBondContact O-N 3.35Å
505	Q	21.1	Very low	24.7	Very low	171 Å²	171	159.6 Å²	159.6	80%	0.799	80%	0.795	S	S	*	*			trans	-72.6	103	171	-76.8	173.3	-9.6	0	0	108.9	R503 H507	R503-Q505 PolarHBondContact O-N 3.1Å; Q505-H507 PolarHBondContact O-N 3.17Å
506	Y	24	Very low	25.1	Very low	195 Å²	195	159.9 Å²	159.9	77%	0.765	79%	0.792	S	S	*	*			trans	-73.9	112.7	165.2	-90.8	-96	0	0	0	109.3	Q504	Q504-Y506 PolarHBondContact O-N 3.35Å
507	H	20.6	Very low	25	Very low	169 Å²	169	162.6 Å²	162.6	78%	0.782	79%	0.791	S	S	*	*			trans	-85.1	118.8	163.3	-89.5	39.5	0	0	0	108.6	Q505	Q505-H507 PolarHBondContact O-N 3.17Å
508	H	26.6	Very low	25.1	Very low	168 Å²	168	164.6 Å²	164.6	78%	0.778	79%	0.792	S	S	*	*			trans	-118.9	151.9	158.6	-98.5	-59.8	0	0	0	110
509	P	25.5	Very low	24.9	Very low	115 Å²	115	167.3 Å²	167.3	75%	0.747	80%	0.795	S	S	*	*			trans	-84.5	154.4	-151.4	-4.6	24	0	0	0	113.1	D511	P509-D511 PolarHBondContact O-N 3.25Å
510	K	25.3	Very low	24.8	Very low	205 Å²	205	165.5 Å²	165.5	89%	0.891	80%	0.795	S	S	*	*			trans	-70.1	113.4	177.1	-63.9	172.4	177.3	177.1	0	110.4
511	D	26.7	Very low	25	Very low	164 Å²	164	162.2 Å²	162.2	88%	0.877	80%	0.798	S	S	*	*			trans	-83.5	124.9	156.8	-82.1	-29.9	0	0	0	109.4	P509	P509-D511 PolarHBondContact O-N 3.25Å
512	P	29.6	Very low	25	Very low	106 Å²	106	159.5 Å²	159.5	69%	0.688	80%	0.798	S	S	*	*			trans	-88.2	120.8	178.6	32.6	-26.9	0	0	0	108.8
513	I	24.6	Very low	25.2	Very low	157 Å²	157	160.1 Å²	160.1	81%	0.805	80%	0.8	S	S	*	*			trans	175.1	99.8	145.8	-82.7	142.8	0	0	0	106
514	N	27.5	Very low	25.3	Very low	141 Å²	141	158.2 Å²	158.2	75%	0.754	80%	0.798	S	S	*	*			trans	154.9	69.9	150.2	-80.5	-23	0	0	0	109.2	Y516	N514-Y516 PolarHBondContact O-N 3.33Å
515	Q	22.7	Very low	25.5	Very low	182 Å²	182	160 Å²	160	85%	0.85	81%	0.806	S	S	*	*			trans	-86.3	79.1	169.6	-146.9	176.4	11.5	0	0	107.6
516	Y	26.5	Very low	26	Very low	207 Å²	207	160.2 Å²	160.2	81%	0.812	81%	0.808	S	S	*	*			trans	-105.6	101.5	162.7	-84.6	-80.5	0	0	0	108.1	N514 Y518	N514-Y516 PolarHBondContact O-N 3.33Å; Y516-Y518 PolarHBondContact O-N 3.27Å
517	N	21.9	Very low	26.4	Very low	121 Å²	121	157.4 Å²	157.4	65%	0.647	81%	0.806	S	S	*	*			trans	-57.9	109.9	174.3	-82.2	-24.9	0	0	0	110.5
518	Y	27	Very low	26.8	Very low	226 Å²	226	156.4 Å²	156.4	89%	0.886	81%	0.806	S	S	*	*			trans	-113.4	80.3	147.8	-83.7	-83.6	0	0	0	107.9	Y516 S520	Y516-Y518 PolarHBondContact O-N 3.27Å; Y518-S520 PolarHBondContact O-N 3.37Å
519	Q	22.7	Very low	27	Very low	167 Å²	167	157.8 Å²	157.8	78%	0.78	81%	0.81	S	S	*	*			trans	-74.6	104.5	159.9	-80.7	172.8	-36.8	0	0	107.5
520	S	25.4	Very low	27.3	Very low	115 Å²	115	159.3 Å²	159.3	80%	0.804	81%	0.811	S	S	*	*			trans	151.2	82.5	147.9	51.4	0	0	0	0	111.9	Y518	Y518-S520 PolarHBondContact O-N 3.37Å
521	A	26.4	Very low	27.4	Very low	104 Å²	104	156.8 Å²	156.8	86%	0.86	81%	0.807	S	S	*	*			trans	-159.9	43.1	155.5	0	0	0	0	0	110.8
522	S	27.8	Very low	27.5	Very low	112 Å²	112	155.2 Å²	155.2	78%	0.783	80%	0.803	S	S	*	*			trans	-112.8	63.8	169.1	61.1	0	0	0	0	108.9
523	T	28.2	Very low	27.5	Very low	130 Å²	130	159 Å²	159	80%	0.798	81%	0.811	S	S	*	*	S	Bend	trans	-154.6	8.8	168.5	-0.7	0	0	0	0	115.9
524	F	27.3	Very low	27.8	Very low	205 Å²	205	163 Å²	163	90%	0.899	82%	0.816	S	S	*	*	S	Bend	trans	-103.5	8.9	-177.1	-102.4	-81.2	0	0	0	116.6
525	E	29.1	Very low	28.1	Very low	199 Å²	199	162 Å²	162	93%	0.93	82%	0.818	S	S	*	*	S	Bend	trans	-99.4	7.8	178.8	-95.4	-172.3	161.8	0	0	115.8
526	Q	31.1	Very low	28.5	Very low	177 Å²	177	160.9 Å²	160.9	83%	0.827	82%	0.818	S	S	*	*	S	Bend	trans	-104.5	-9.8	-179.8	-104.6	173.5	-10.6	0	0	117.2
527	D	31.1	Very low	28.6	Very low	136 Å²	136	162.4 Å²	162.4	73%	0.727	82%	0.824	S	S	*	*	S	Bend	trans	-103.3	3.9	-175.3	-81.7	-16.2	0	0	0	116.6
528	N	29.4	Very low	28.9	Very low	148 Å²	148	160.8 Å²	160.8	79%	0.791	83%	0.827	S	S	*	*	S	Bend	trans	-102	14.7	177.2	-109.8	-16	0	0	0	115.6
529	K	31.2	Very low	29.1	Very low	196 Å²	196	165 Å²	165	85%	0.852	84%	0.844	S	S	*	*	S	Bend	trans	-104	7.7	172.7	-86.2	-173.6	177.4	178	0	115.4
530	L	31.6	Very low	29.5	Very low	148 Å²	148	165 Å²	165	78%	0.775	85%	0.847	S	S	*	*	S	Bend	trans	-114.3	6	-176.7	-87.9	160.6	0	0	0	116.4
531	L	28.4	Very low	29.7	Very low	152 Å²	152	167.6 Å²	167.6	80%	0.796	85%	0.849	S	S	*	*	S	Bend	trans	-109.8	16.7	-178.2	-77.6	168.2	0	0	0	116.1
532	T	29.2	Very low	29.8	Very low	131 Å²	131	171.1 Å²	171.1	80%	0.804	85%	0.849	S	S	*	*			trans	-121.3	53.1	173.3	49	0	0	0	0	112.8
533	Q	29	Very low	30	Very low	184 Å²	184	174.6 Å²	174.6	86%	0.86	85%	0.853	S	S	*	*			trans	-139.3	84.9	159.4	-68.4	-171.4	-0.5	0	0	108.9
534	R	30.4	Very low	30.1	Very low	241 Å²	241	177.4 Å²	177.4	91%	0.909	86%	0.856	S	S	*	*			trans	-88.1	115.9	160.6	-81.6	-171.1	176.5	-170.5	-0.7	107.1
535	P	33.4	Very low	30.3	Very low	121 Å²	121	175.5 Å²	175.5	79%	0.786	85%	0.853	S	S	*	*	P	Polyproline II helix	trans	-78.7	145.9	177.6	29.7	-29.8	0	0	0	111.2
536	D	32.1	Very low	30.3	Very low	159 Å²	159	173.9 Å²	173.9	85%	0.85	85%	0.848	S	S	*	*	P	Polyproline II helix	trans	-56.8	143.6	-177.4	-68.1	-56.8	0	0	0	114
537	Y	29	Very low	30.3	Very low	239 Å²	239	173.6 Å²	173.6	94%	0.937	85%	0.849	S	S	*	*	P	Polyproline II helix	trans	-65.2	124.2	169.2	-73.4	-95.6	0	0	0	110.3
538	A	26.8	Very low	30.2	Very low	87 Å²	87	176.8 Å²	176.8	72%	0.719	86%	0.86	S	S	*	*			trans	-142.3	116.8	163.1	0	0	0	0	0	110.4
539	Y	32.3	Very low	30.3	Very low	315 Å²	315	179.4 Å²	179.4	100%	1.235	87%	0.866	S	S	*	*			trans	72	0	175.4	-67.7	-79.8	0	0	0	118.8

Retrieved 539 of 539 residues in 153.2 ms (Link to these results)

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