V1AR_HUMAN Loading...

Vasopressin V1a receptor

Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.

AlphaFold DB , UniProt , Accession P37288, Species HUMAN (Homo sapiens, Human), Gene AVPR1A, Length 418 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	44.6	Very low	33.5	Very low	52 Å²	52	77 Å²	77	26%	0.256	52%	0.521	S	S	.	.				0	116.9	0	-75.3	171.2	-165.7	0	0	107.6	V132 F189 Y216 M220	M1-V132 HydrophobicContact CE-CG2 3.12Å; M1-F189 HydrophobicContact SD-CZ 4.43Å; M1-Y216 HydrophobicContact SD-CE1 3.88Å; M1-Y216 PolarHBondContact SD-OH 3.45Å; M1-M220 HydrophobicContact CE-CE 3.58Å; M1-M220 HydrophobicContact SD-CE 4.21Å
2	R	44.2	Very low	33.2	Very low	86 Å²	86	80.2 Å²	80.2	33%	0.325	55%	0.545	S	S	.	.			trans	-78.7	120.9	171.3	-66	-178.9	-176.8	176.5	7.9	108	D112	R2-D112 IonicContact NH2-OD1 2.76Å; R2-D112 PolarHBondContact NH2-OD1 3.39Å
3	L	40	Very low	32.7	Very low	46 Å²	46	79.3 Å²	79.3	24%	0.241	56%	0.558	C	S	.	*			trans	-125	120.9	173.4	-62.3	170.7	0	0	0	105.5	A205 F207 Y216 V217	L3-A205 HydrophobicContact CD2-CB 3.55Å; L3-F207 HydrophobicContact CD2-CE2 4.08Å; L3-F207 HydrophobicContact CD2-CZ 4.19Å; L3-Y216 HydrophobicContact CD1-CD1 3.92Å; L3-Y216 HydrophobicContact CD1-CE1 4.13Å; L3-Y216 HydrophobicContact CD2-CD1 4.39Å; L3-Y216 HydrophobicContact CD2-CE1 4.36Å; L3-V217 HydrophobicContact CD1-CG2 3.34Å
4	S	34.5	Very low	32.4	Very low	21 Å²	21	84.8 Å²	84.8	15%	0.147	58%	0.577	C	S	.	*			trans	-154.8	99.3	-170.4	-111.8	0	0	0	0	110	G6 W204 E324	S4-G6 PolarHBondContact O-N 3.02Å; S4-W204 VanDerWaalsContact C-CZ2 3.48Å; S4-W204 WeakPolarHBondContact O-CH2 3.31Å; S4-W204 WeakPolarHBondContact O-CZ2 3.39Å; S4-W204 VanDerWaalsContact O-CZ3 3.32Å; S4-W204 WeakPolarHBondContact O-CZ3 3.26Å; S4-E324 WeakPolarHBondContact CA-OE1 3.12Å; S4-E324 WeakPolarHBondContact CB-OE1 3.47Å; S4-E324 WeakPolarHBondContact OG-CA 3.48Å; S4-E324 WeakPolarHBondContact OG-CB 3.44Å; S4-E324 WeakPolarHBondContact OG-CG 3.28Å; S4-E324 PolarHBondContact OG-OE1 3.37Å
5	A	30.5	Very low	32.1	Very low	92 Å²	92	85.8 Å²	85.8	76%	0.76	59%	0.586	S	S	*	*			trans	-40.4	115.5	-170.3	0	0	0	0	0	111.5	E324	A5-E324 PolarHBondContact N-OE1 3.47Å
6	G	29.3	Very low	32.1	Very low	36 Å²	36	87.2 Å²	87.2	37%	0.371	60%	0.596	S	S	.	*			trans	-51.2	153.4	-174.5	0	0	0	0	0	111.7	S4 D8	S4-G6 PolarHBondContact O-N 3.02Å; G6-D8 PolarHBondContact O-N 3.25Å
7	P	27.8	Very low	32.3	Very low	89 Å²	89	88.1 Å²	88.1	58%	0.578	60%	0.6	S	S	*	*	S	Bend	trans	-59.6	139.5	172.2	30.1	-32	0	0	0	106.9
8	D	30.4	Very low	32.2	Very low	145 Å²	145	95.9 Å²	95.9	78%	0.775	62%	0.615	S	S	*	*			trans	89.8	62.6	176.5	-43.6	-35	0	0	0	116.3	G6	G6-D8 PolarHBondContact O-N 3.25Å
9	A	31.1	Very low	32.2	Very low	93 Å²	93	102.8 Å²	102.8	77%	0.769	63%	0.628	S	S	*	*			trans	-114.5	79.3	141.7	0	0	0	0	0	108	P11	A9-P11 VanDerWaalsContact O-CD 3.28Å; A9-P11 WeakPolarHBondContact O-CD 3.22Å
10	G	25.2	Very low	32.1	Very low	78 Å²	78	103 Å²	103	80%	0.804	63%	0.631	S	S	*	*			trans	-76.9	122.4	158.5	0	0	0	0	0	108.6
11	P	31.4	Very low	32	Very low	109 Å²	109	104.9 Å²	104.9	71%	0.708	64%	0.637	S	S	*	*			trans	-106.7	107.9	159.2	19.3	2.2	0	0	0	107.3	A9 G13	A9-P11 VanDerWaalsContact O-CD 3.28Å; A9-P11 WeakPolarHBondContact O-CD 3.22Å; P11-G13 PolarHBondContact O-N 2.79Å
12	S	29	Very low	31.5	Very low	115 Å²	115	107.5 Å²	107.5	80%	0.804	67%	0.666	S	S	*	*				8.1	115.4	127.5	52.5	0	0	0	0	115.9
13	G	26.7	Very low	30.9	Very low	69 Å²	69	109.7 Å²	109.7	71%	0.711	69%	0.69	S	S	*	*			trans	80.1	130	132.6	0	0	0	0	0	118.5	P11	P11-G13 PolarHBondContact O-N 2.79Å
14	N	28.4	Very low	30.7	Very low	156 Å²	156	111.2 Å²	111.2	83%	0.834	72%	0.716	S	S	*	*			trans	84.6	95	152.2	-77.4	2.9	0	0	0	119.4
15	S	28.2	Very low	30.6	Very low	100 Å²	100	115.5 Å²	115.5	70%	0.699	75%	0.753	S	S	*	*				53.9	109.5	118.8	40.6	0	0	0	0	118.7
16	S	31.6	Very low	30.7	Very low	108 Å²	108	114.5 Å²	114.5	76%	0.755	75%	0.751	S	S	*	*				169.8	156.4	100.2	43.5	0	0	0	0	112.5
17	P	35.5	Very low	30.8	Very low	103 Å²	103	120.5 Å²	120.5	67%	0.669	78%	0.775	S	S	*	*			trans	-119.5	115.3	-154.7	33.8	-16.1	0	0	0	113.7
18	W	31.6	Very low	31.3	Very low	228 Å²	228	122.7 Å²	122.7	86%	0.864	79%	0.787	S	S	*	*			trans	-154.8	110.9	168.7	-55.7	93.3	0	0	0	106.7
19	W	31.2	Very low	31.5	Very low	228 Å²	228	121.2 Å²	121.2	86%	0.864	79%	0.788	S	S	*	*				-163.7	151	60.1	39.3	-94.7	0	0	0	111
20	P	31.6	Very low	31.6	Very low	105 Å²	105	128 Å²	128	68%	0.682	79%	0.793	S	S	*	*			trans	-105.2	169.6	172.5	38.9	-30.2	0	0	0	113
21	L	29.6	Very low	32.2	Very low	144 Å²	144	133.7 Å²	133.7	75%	0.754	80%	0.799	S	S	*	*			trans	93.4	103.5	160.9	-61	156.7	0	0	0	118.4
22	A	34.3	Very low	32.2	Very low	106 Å²	106	132.8 Å²	132.8	88%	0.876	80%	0.801	S	S	*	*				-144.5	91.8	126.7	0	0	0	0	0	108.8
23	T	31.7	Very low	32.3	Very low	133 Å²	133	136.7 Å²	136.7	82%	0.816	81%	0.806	S	S	*	*			trans	-71.4	116.9	163.1	41.7	0	0	0	0	109
24	G	35.1	Very low	32.8	Very low	77 Å²	77	137.9 Å²	137.9	79%	0.794	81%	0.81	S	S	*	*			trans	-137	98.4	167.7	0	0	0	0	0	108.9
25	A	31.6	Very low	33	Very low	112 Å²	112	139 Å²	139	93%	0.926	82%	0.815	S	S	*	*			trans	-66.7	139.6	174.5	0	0	0	0	0	110.9
26	G	34.2	Very low	33.1	Very low	70 Å²	70	137.7 Å²	137.7	72%	0.722	82%	0.816	S	S	*	*			trans	-171.9	95.6	173	0	0	0	0	0	111.2	T28	G26-T28 PolarHBondContact O-N 3.19Å
27	N	30.2	Very low	33	Very low	162 Å²	162	142.3 Å²	142.3	87%	0.866	83%	0.826	S	S	*	*			trans	-48.6	121.6	170.6	-87.5	-20	0	0	0	112.1
28	T	39.5	Very low	32.8	Very low	136 Å²	136	141 Å²	141	83%	0.834	83%	0.831	S	S	*	*			trans	-148.3	92.4	143.8	21.6	0	0	0	0	109.6	G26 R30	G26-T28 PolarHBondContact O-N 3.19Å; T28-R30 PolarHBondContact O-N 3.38Å
29	S	33.1	Very low	32.9	Very low	113 Å²	113	138.9 Å²	138.9	79%	0.79	84%	0.836	S	S	*	*			trans	-69.5	105.6	157.4	43.8	0	0	0	0	109.6
30	R	34	Very low	33.2	Very low	236 Å²	236	130.3 Å²	130.3	89%	0.891	82%	0.819	S	S	*	*			trans	-173.5	146.2	154.2	-104.4	167	-178.5	175.1	0.3	108.1	T28	T28-R30 PolarHBondContact O-N 3.38Å
31	E	38.4	Very low	33.7	Very low	198 Å²	198	130.1 Å²	130.1	93%	0.925	82%	0.818	S	S	*	*			trans	83.1	57.7	-175.7	-58.5	178.3	122.8	0	0	115.6
32	A	30.7	Very low	34.5	Very low	90 Å²	90	129.4 Å²	129.4	74%	0.744	82%	0.822	S	S	*	*			trans	-76.5	151.8	135.4	0	0	0	0	0	109
33	E	31.8	Very low	35.3	Very low	197 Å²	197	135 Å²	135	92%	0.921	82%	0.82	S	S	*	*			trans	86.5	75.8	169.4	-55.4	-171.5	123.2	0	0	118.1
34	A	36.3	Very low	36.6	Very low	94 Å²	94	133.4 Å²	133.4	78%	0.777	81%	0.807	S	S	*	*			trans	-145.4	92.9	142.6	0	0	0	0	0	109.9
35	L	33.3	Very low	38	Very low	180 Å²	180	134.9 Å²	134.9	94%	0.942	80%	0.8	S	S	*	*			trans	21.8	106.7	135.7	-60.2	158.8	0	0	0	114.4
36	G	29.4	Very low	40	Very low	71 Å²	71	132.6 Å²	132.6	73%	0.732	77%	0.768	S	S	*	*				82.4	71.9	69.6	0	0	0	0	0	111.3
37	E	30.1	Very low	42.2	Very low	206 Å²	206	133.3 Å²	133.3	96%	0.963	76%	0.755	S	S	*	*			trans	-171.1	127.8	156.4	-111.8	-177	119.6	0	0	111.8
38	G	32.1	Very low	44.8	Very low	74 Å²	74	129.8 Å²	129.8	76%	0.763	73%	0.733	S	S	*	*			trans	93.8	61.6	147.9	0	0	0	0	0	119.4	G40	G38-G40 PolarHBondContact O-N 3.24Å
39	N	32.3	Very low	47	Very low	184 Å²	184	129.2 Å²	129.2	98%	0.984	72%	0.721	S	S	*	*			trans	-72.2	64.4	160.6	-158.6	23.8	0	0	0	111.1
40	G	37.9	Very low	49.4	Very low	49 Å²	49	125.1 Å²	125.1	51%	0.505	69%	0.69	S	S	.	*			trans	-104.8	152	171.1	0	0	0	0	0	110.8	G38	G38-G40 PolarHBondContact O-N 3.24Å
41	P	41.6	Very low	51.9	Low	100 Å²	100	114.2 Å²	114.2	65%	0.649	65%	0.651	S	S	*	*	P	Polyproline II helix	trans	-58.3	149.3	177.1	26.6	-33.3	0	0	0	109.9	R43	P41-R43 PolarHBondContact O-N 2.92Å
42	P	47.5	Very low	54.3	Low	129 Å²	129	110.4 Å²	110.4	84%	0.838	63%	0.631	S	S	*	*	P	Polyproline II helix	trans	-54.5	116.2	-176.5	22.4	-31.1	0	0	0	108.4	D44	P42-D44 PolarHBondContact O-N 3.45Å
43	R	51.4	Low	57.1	Low	224 Å²	224	110.9 Å²	110.9	85%	0.845	62%	0.621	S	S	*	*	P	Polyproline II helix	trans	-58.8	137	169.3	-71.9	178.6	173.1	158.6	-1.4	106	P41 V45	P41-R43 PolarHBondContact O-N 2.92Å; R43-V45 HydrophobicContact CB-CG2 4.26Å; R43-V45 WeakPolarHBondContact O-CG2 3.43Å; R43-V45 PolarHBondContact O-N 3.03Å
44	D	59	Low	59.8	Low	99 Å²	99	102.3 Å²	102.3	53%	0.529	58%	0.58	S	S	.	*			trans	-63.4	79.2	174	-162.2	-3.3	0	0	0	107.3	P42 R46 Y115 R116	P42-D44 PolarHBondContact O-N 3.45Å; D44-R46 PolarHBondContact O-N 3.13Å; D44-Y115 WeakPolarHBondContact CB-OH 3.41Å; D44-Y115 PolarHBondContact O-OH 3.28Å; D44-Y115 VanDerWaalsContact O-OH 3.05Å; D44-Y115 PolarHBondContact OD1-OH 3.14Å; D44-Y115 PolarHBondContact OD2-OH 3.46Å; D44-Y115 VanDerWaalsContact OD2-OH 3.04Å; D44-R116 IonicContact OD2-CZ 3.36Å; D44-R116 IonicContact OD2-NH2 3.56Å; D44-R116 PolarHBondContact OD2-NH2 3.11Å
45	V	64.2	Low	62.4	Low	108 Å²	108	99.7 Å²	99.7	66%	0.655	55%	0.553	S	S	*	*			trans	-82.2	108.6	-173.3	179	0	0	0	0	107.7	R43	R43-V45 HydrophobicContact CB-CG2 4.26Å; R43-V45 WeakPolarHBondContact O-CG2 3.43Å; R43-V45 PolarHBondContact O-N 3.03Å
46	R	73.4	Confident	65.3	Low	65 Å²	65	93.7 Å²	93.7	25%	0.245	53%	0.529	C	S	.	.			trans	-77.1	133.6	170	176	175.5	69	172.2	0.3	110.5	D44 E48 A51 D112 Y115 E326	D44-R46 PolarHBondContact O-N 3.13Å; R46-E48 IonicContact CZ-OE1 2.93Å; R46-E48 VanDerWaalsContact CZ-OE1 3.27Å; R46-E48 IonicContact CZ-OE2 2.89Å; R46-E48 IonicContact NE-OE1 3.89Å; R46-E48 PolarHBondContact NE-OE1 3.19Å; R46-E48 IonicContact NE-OE2 2.81Å; R46-E48 VanDerWaalsContact NH2-CD 3.27Å; R46-E48 IonicContact NH2-OE1 3.26Å; R46-E48 PolarHBondContact NH2-OE1 3.41Å; R46-E48 IonicContact NH2-OE2 3.39Å; R46-E48 PolarHBondContact NH2-OE2 3.32Å; R46-E48 PolarHBondContact O-N 3.19Å; R46-A51 HydrophobicContact CG-CB 4.18Å; R46-D112 PolarHBondContact NH1-O 3.26Å; R46-Y115 HydrophobicContact CB-CD2 4.39Å; R46-Y115 HydrophobicContact CB-CE2 3.83Å; R46-Y115 HydrophobicContact CG-CE2 4.35Å; R46-E326 WeakPolarHBondContact CA-OE1 3.43Å
47	N	80.6	Confident	68.2	Low	84 Å²	84	92.5 Å²	92.5	45%	0.449	51%	0.508	S	S	.	.			trans	-67.7	94.2	163.8	-167	-18	0	0	0	111.5	E49 L50 A51 E326	N47-E49 VanDerWaalsContact C-N 3.3Å; N47-E49 PolarHBondContact O-N 3.07Å; N47-E49 PolarHBondContact OD1-N 3.3Å; N47-L50 HydrophobicContact CB-CB 4.12Å; N47-L50 PolarHBondContact O-N 3.05Å; N47-A51 PolarHBondContact O-N 3.03Å; N47-E326 PolarHBondContact N-OE1 2.84Å
48	E	84.1	Confident	71.2	Confident	89 Å²	89	83 Å²	83	42%	0.416	46%	0.464	S	S	.	.	H	α-helix	trans	-57.7	-37	-176.2	-75.5	-65.4	155.5	0	0	113.8	R46 A51 K52	R46-E48 IonicContact CZ-OE1 2.93Å; R46-E48 VanDerWaalsContact CZ-OE1 3.27Å; R46-E48 IonicContact CZ-OE2 2.89Å; R46-E48 IonicContact NE-OE1 3.89Å; R46-E48 PolarHBondContact NE-OE1 3.19Å; R46-E48 IonicContact NE-OE2 2.81Å; R46-E48 VanDerWaalsContact NH2-CD 3.27Å; R46-E48 IonicContact NH2-OE1 3.26Å; R46-E48 PolarHBondContact NH2-OE1 3.41Å; R46-E48 IonicContact NH2-OE2 3.39Å; R46-E48 PolarHBondContact NH2-OE2 3.32Å; R46-E48 PolarHBondContact O-N 3.19Å; E48-A51 PolarHBondContact O-N 3.04Å; E48-K52 VanDerWaalsContact O-CG 3.29Å; E48-K52 WeakPolarHBondContact O-CG 3.39Å; E48-K52 PolarHBondContact O-N 3.41Å
49	E	86.2	Confident	74.2	Confident	123 Å²	123	81.5 Å²	81.5	58%	0.575	44%	0.444	S	S	*	.	H	α-helix	trans	-69.7	-40.5	-179.2	-66.2	-56.4	119.6	0	0	111.4	N47 A51 K52 L53	N47-E49 VanDerWaalsContact C-N 3.3Å; N47-E49 PolarHBondContact O-N 3.07Å; N47-E49 PolarHBondContact OD1-N 3.3Å; E49-A51 VanDerWaalsContact C-N 3.34Å; E49-K52 PolarHBondContact O-N 3.13Å; E49-K52 IonicContact OE1-NZ 3.27Å; E49-K52 PolarHBondContact OE1-NZ 3.18Å; E49-L53 WeakPolarHBondContact O-CB 3.39Å; E49-L53 PolarHBondContact O-N 3.27Å; E49-L53 VanDerWaalsContact O-N 3.07Å
50	L	83.6	Confident	77.1	Confident	27 Å²	27	77.2 Å²	77.2	14%	0.141	42%	0.424	C	S	.	.	H	α-helix	trans	-64.7	-41	174	-176.4	60.4	0	0	0	111.1	N47 L53 E54 P328 T331	N47-L50 HydrophobicContact CB-CB 4.12Å; N47-L50 PolarHBondContact O-N 3.05Å; L50-L53 PolarHBondContact O-N 3.45Å; L50-E54 WeakPolarHBondContact O-CB 3.46Å; L50-E54 PolarHBondContact O-N 3.33Å; L50-P328 HydrophobicContact CD1-CB 4.13Å; L50-P328 HydrophobicContact CD2-CB 4.17Å; L50-T331 HydrophobicContact CD1-CG2 4.44Å
51	A	85.4	Confident	79.8	Confident	8 Å²	8	75 Å²	75	7%	0.066	40%	0.401	C	S	.	.	H	α-helix	trans	-64.5	-44.4	177.9	0	0	0	0	0	112.2	R46 N47 E48 E49 L53 E54 I55	R46-A51 HydrophobicContact CG-CB 4.18Å; N47-A51 PolarHBondContact O-N 3.03Å; E48-A51 PolarHBondContact O-N 3.04Å; E49-A51 VanDerWaalsContact C-N 3.34Å; A51-L53 VanDerWaalsContact C-N 3.32Å; A51-L53 PolarHBondContact O-N 3.01Å; A51-E54 PolarHBondContact O-N 3Å; A51-I55 WeakPolarHBondContact O-CB 3.48Å; A51-I55 WeakPolarHBondContact O-CD1 3.5Å; A51-I55 WeakPolarHBondContact O-CG1 3.45Å; A51-I55 PolarHBondContact O-N 3.24Å
52	K	90.4	Very high	82.3	Confident	117 Å²	117	72.2 Å²	72.2	51%	0.509	38%	0.379	S	S	.	.	H	α-helix	trans	-59.5	-43	174.8	-72.5	170.6	-167.5	166	0	111.7	E48 E49 A56	E48-K52 VanDerWaalsContact O-CG 3.29Å; E48-K52 WeakPolarHBondContact O-CG 3.39Å; E48-K52 PolarHBondContact O-N 3.41Å; E49-K52 PolarHBondContact O-N 3.13Å; E49-K52 IonicContact OE1-NZ 3.27Å; E49-K52 PolarHBondContact OE1-NZ 3.18Å; K52-A56 WeakPolarHBondContact O-CB 3.41Å; K52-A56 PolarHBondContact O-N 3.36Å
53	L	89.2	Confident	84.6	Confident	101 Å²	101	68.2 Å²	68.2	53%	0.529	36%	0.356	S	S	.	.	H	α-helix	trans	-63.9	-46.1	176.8	-179.3	65.2	0	0	0	111.5	E49 L50 A51 A56 V57	E49-L53 WeakPolarHBondContact O-CB 3.39Å; E49-L53 PolarHBondContact O-N 3.27Å; E49-L53 VanDerWaalsContact O-N 3.07Å; L50-L53 PolarHBondContact O-N 3.45Å; A51-L53 VanDerWaalsContact C-N 3.32Å; A51-L53 PolarHBondContact O-N 3.01Å; L53-A56 PolarHBondContact O-N 3.24Å; L53-V57 HydrophobicContact CD1-CG2 4.3Å; L53-V57 VanDerWaalsContact O-CG2 3.31Å; L53-V57 WeakPolarHBondContact O-CG2 3.3Å; L53-V57 PolarHBondContact O-N 3.5Å
54	E	88.3	Confident	86.7	Confident	16 Å²	16	60 Å²	60	8%	0.075	33%	0.331	C	S	.	.	H	α-helix	trans	-58.2	-48.9	176.6	-179.6	170	-159.7	0	0	111.1	L50 A51 A56 V57 L58 T331 L335	L50-E54 WeakPolarHBondContact O-CB 3.46Å; L50-E54 PolarHBondContact O-N 3.33Å; A51-E54 PolarHBondContact O-N 3Å; E54-A56 PolarHBondContact O-N 3.34Å; E54-V57 PolarHBondContact O-N 3.22Å; E54-L58 HydrophobicContact CG-CD1 3.79Å; E54-L58 HydrophobicContact CG-CG 4.35Å; E54-L58 WeakPolarHBondContact O-CB 3.49Å; E54-L58 VanDerWaalsContact O-CG 3.25Å; E54-L58 WeakPolarHBondContact O-CG 3.41Å; E54-L58 PolarHBondContact O-N 3.06Å; E54-T331 HydrophobicContact CB-CG2 4.06Å; E54-T331 HydrophobicContact CG-CG2 3.93Å; E54-L335 HydrophobicContact CG-CD2 4.38Å
55	I	91.7	Very high	88.3	Confident	40 Å²	40	55.3 Å²	55.3	21%	0.205	31%	0.306	C	S	.	.	H	α-helix	trans	-59.3	-45.9	177.4	-66.4	162	0	0	0	111	A51 L58 A59 D112 I113	A51-I55 WeakPolarHBondContact O-CB 3.48Å; A51-I55 WeakPolarHBondContact O-CD1 3.5Å; A51-I55 WeakPolarHBondContact O-CG1 3.45Å; A51-I55 PolarHBondContact O-N 3.24Å; I55-L58 PolarHBondContact O-N 3.29Å; I55-A59 VanDerWaalsContact O-CB 3.27Å; I55-A59 WeakPolarHBondContact O-CB 3.47Å; I55-A59 PolarHBondContact O-N 3.36Å; I55-D112 HydrophobicContact CD1-CB 4.41Å; I55-D112 HydrophobicContact CG1-CB 3.8Å; I55-I113 HydrophobicContact CD1-CG1 3.89Å; I55-I113 HydrophobicContact CG1-CG1 4.04Å; I55-I113 HydrophobicContact CG2-CD1 4.21Å; I55-I113 HydrophobicContact CG2-CG1 3.9Å
56	A	92.9	Very high	89.9	Confident	54 Å²	54	51.5 Å²	51.5	45%	0.446	28%	0.283	S	S	.	.	H	α-helix	trans	-61.6	-45.8	179.4	0	0	0	0	0	111.8	K52 L53 E54 A59 V60	K52-A56 WeakPolarHBondContact O-CB 3.41Å; K52-A56 PolarHBondContact O-N 3.36Å; L53-A56 PolarHBondContact O-N 3.24Å; E54-A56 PolarHBondContact O-N 3.34Å; A56-A59 PolarHBondContact O-N 3.27Å; A56-V60 WeakPolarHBondContact O-CG2 3.22Å; A56-V60 PolarHBondContact O-N 2.93Å
57	V	91.3	Very high	90.8	Very high	45 Å²	45	54.1 Å²	54.1	27%	0.273	30%	0.301	S	S	.	.	H	α-helix	trans	-67	-42.4	179.1	177.2	0	0	0	0	111.1	L53 E54 V60 T61 L335	L53-V57 HydrophobicContact CD1-CG2 4.3Å; L53-V57 VanDerWaalsContact O-CG2 3.31Å; L53-V57 WeakPolarHBondContact O-CG2 3.3Å; L53-V57 PolarHBondContact O-N 3.5Å; E54-V57 PolarHBondContact O-N 3.22Å; V57-V60 PolarHBondContact O-N 3.35Å; V57-T61 VanDerWaalsContact O-CB 3.26Å; V57-T61 WeakPolarHBondContact O-CB 3.35Å; V57-T61 PolarHBondContact O-N 2.84Å; V57-T61 PolarHBondContact O-OG1 3.01Å; V57-L335 HydrophobicContact CB-CD1 4.11Å; V57-L335 HydrophobicContact CB-CD2 4.12Å; V57-L335 HydrophobicContact CG1-CB 4.24Å; V57-L335 HydrophobicContact CG1-CD1 4.05Å; V57-L335 HydrophobicContact CG1-CD2 3.84Å; V57-L335 HydrophobicContact CG1-CG 4.26Å; V57-L335 HydrophobicContact CG2-CD1 4.4Å
58	L	92.1	Very high	91.4	Very high	8 Å²	8	50.9 Å²	50.9	4%	0.042	29%	0.288	C	S	.	.	H	α-helix	trans	-64	-39.8	176.6	-71	172.7	0	0	0	111.8	E54 I55 T61 F62 V105 Q108 M109 D112 L335	E54-L58 HydrophobicContact CG-CD1 3.79Å; E54-L58 HydrophobicContact CG-CG 4.35Å; E54-L58 WeakPolarHBondContact O-CB 3.49Å; E54-L58 VanDerWaalsContact O-CG 3.25Å; E54-L58 WeakPolarHBondContact O-CG 3.41Å; E54-L58 PolarHBondContact O-N 3.06Å; I55-L58 PolarHBondContact O-N 3.29Å; L58-T61 PolarHBondContact O-N 3.34Å; L58-F62 VanDerWaalsContact O-CB 3.23Å; L58-F62 WeakPolarHBondContact O-CB 3.31Å; L58-F62 PolarHBondContact O-N 3.2Å; L58-V105 HydrophobicContact CB-CG1 4.36Å; L58-V105 HydrophobicContact CD2-CG1 3.99Å; L58-Q108 HydrophobicContact CD1-CG 3.91Å; L58-M109 HydrophobicContact CB-CB 4.05Å; L58-M109 HydrophobicContact CB-CG 4.18Å; L58-M109 HydrophobicContact CD1-CB 4.24Å; L58-D112 WeakPolarHBondContact CD1-OD2 3.22Å; L58-L335 HydrophobicContact CD2-CD2 3.67Å; L58-L335 HydrophobicContact CG-CD2 3.74Å
59	A	95.1	Very high	91.9	Very high	41 Å²	41	46.7 Å²	46.7	34%	0.339	27%	0.268	S	S	.	.	H	α-helix	trans	-63.4	-46	176.9	0	0	0	0	0	111.9	I55 A56 F62 A63 M109	I55-A59 VanDerWaalsContact O-CB 3.27Å; I55-A59 WeakPolarHBondContact O-CB 3.47Å; I55-A59 PolarHBondContact O-N 3.36Å; A56-A59 PolarHBondContact O-N 3.27Å; A59-F62 PolarHBondContact O-N 3.39Å; A59-A63 WeakPolarHBondContact O-CB 3.33Å; A59-A63 PolarHBondContact O-N 3.28Å; A59-M109 VanDerWaalsContact CA-SD 3.59Å; A59-M109 HydrophobicContact CB-SD 3.76Å
60	V	94.3	Very high	92.2	Very high	94 Å²	94	43.2 Å²	43.2	57%	0.57	26%	0.258	S	S	*	.	H	α-helix	trans	-63.4	-46.2	175.5	172.9	0	0	0	0	110.7	A56 V57 F62 A63 V64	A56-V60 WeakPolarHBondContact O-CG2 3.22Å; A56-V60 PolarHBondContact O-N 2.93Å; V57-V60 PolarHBondContact O-N 3.35Å; V60-F62 VanDerWaalsContact C-N 3.35Å; V60-F62 PolarHBondContact O-N 3.14Å; V60-A63 PolarHBondContact O-N 3.22Å; V60-V64 HydrophobicContact CG1-CG2 4.27Å; V60-V64 WeakPolarHBondContact O-CB 3.09Å; V60-V64 VanDerWaalsContact O-CG2 3.3Å; V60-V64 WeakPolarHBondContact O-CG2 3.25Å; V60-V64 PolarHBondContact O-N 3.05Å
61	T	92.8	Very high	92.6	Very high	4 Å²	4	43.4 Å²	43.4	3%	0.025	26%	0.261	C	S	.	.	H	α-helix	trans	-59.8	-45.6	178.5	-59.8	0	0	0	0	111	V57 L58 V64 A65 C342	V57-T61 VanDerWaalsContact O-CB 3.26Å; V57-T61 WeakPolarHBondContact O-CB 3.35Å; V57-T61 PolarHBondContact O-N 2.84Å; V57-T61 PolarHBondContact O-OG1 3.01Å; L58-T61 PolarHBondContact O-N 3.34Å; T61-V64 PolarHBondContact O-N 2.88Å; T61-A65 WeakPolarHBondContact O-CB 3.31Å; T61-A65 PolarHBondContact O-N 2.93Å; T61-C342 PolarHBondContact O-SG 2.87Å; T61-C342 VanDerWaalsContact O-SG 3.4Å
62	F	95.1	Very high	92.8	Very high	41 Å²	41	43.6 Å²	43.6	18%	0.18	26%	0.261	C	S	.	.	H	α-helix	trans	-59.1	-50.8	176.3	177.9	-103.4	0	0	0	111.4	L58 A59 V60 V64 A65 V66 A101 F102 V105 L106	L58-F62 VanDerWaalsContact O-CB 3.23Å; L58-F62 WeakPolarHBondContact O-CB 3.31Å; L58-F62 PolarHBondContact O-N 3.2Å; A59-F62 PolarHBondContact O-N 3.39Å; V60-F62 VanDerWaalsContact C-N 3.35Å; V60-F62 PolarHBondContact O-N 3.14Å; F62-V64 PolarHBondContact O-N 3.43Å; F62-A65 PolarHBondContact O-N 3.38Å; F62-V66 HydrophobicContact CD2-CG2 4.05Å; F62-V66 HydrophobicContact CE1-CG2 4.21Å; F62-V66 HydrophobicContact CE2-CG2 3.69Å; F62-V66 HydrophobicContact CG-CG2 4.45Å; F62-V66 HydrophobicContact CZ-CG2 3.79Å; F62-V66 WeakPolarHBondContact O-CB 3.24Å; F62-V66 VanDerWaalsContact O-CG2 3.3Å; F62-V66 WeakPolarHBondContact O-CG2 3.48Å; F62-V66 PolarHBondContact O-N 3.42Å; F62-A101 HydrophobicContact CD2-CB 4.14Å; F62-A101 WeakPolarHBondContact CD2-O 3.21Å; F62-A101 HydrophobicContact CE2-CB 4.33Å; F62-A101 WeakPolarHBondContact CE2-O 3.48Å; F62-F102 HydrophobicContact CE2-CD1 4.18Å; F62-F102 HydrophobicContact CE2-CE1 4.31Å; F62-F102 HydrophobicContact CE2-CG 4.49Å; F62-F102 HydrophobicContact CZ-CD1 4.21Å; F62-F102 AromaticContact CZ-CE1 3.93Å; F62-F102 HydrophobicContact CZ-CE1 3.93Å; F62-F102 HydrophobicContact CZ-CZ 4.39Å; F62-V105 HydrophobicContact CB-CG1 3.92Å; F62-L106 HydrophobicContact CD2-CB 4.01Å; F62-L106 HydrophobicContact CE2-CB 3.74Å; F62-L106 HydrophobicContact CE2-CD2 4.29Å; F62-L106 HydrophobicContact CE2-CG 4.43Å; F62-L106 HydrophobicContact CZ-CB 4.39Å; F62-L106 HydrophobicContact CZ-CD1 4.49Å; F62-L106 HydrophobicContact CZ-CD2 4.26Å
63	A	95.9	Very high	92.9	Very high	44 Å²	44	39.7 Å²	39.7	36%	0.364	25%	0.246	S	C	.	.	H	α-helix	trans	-59.8	-48.3	179.5	0	0	0	0	0	111.8	A59 V60 V66 L67	A59-A63 WeakPolarHBondContact O-CB 3.33Å; A59-A63 PolarHBondContact O-N 3.28Å; V60-A63 PolarHBondContact O-N 3.22Å; A63-V66 PolarHBondContact O-N 3.29Å; A63-L67 VanDerWaalsContact O-CB 3.27Å; A63-L67 WeakPolarHBondContact O-CB 3.36Å; A63-L67 WeakPolarHBondContact O-CG 3.34Å; A63-L67 PolarHBondContact O-N 3.31Å
64	V	94.5	Very high	92.9	Very high	52 Å²	52	38.1 Å²	38.1	32%	0.315	24%	0.237	S	C	.	.	H	α-helix	trans	-64.4	-43.5	179.3	174.4	0	0	0	0	111.3	V60 T61 F62 G68 C342	V60-V64 HydrophobicContact CG1-CG2 4.27Å; V60-V64 WeakPolarHBondContact O-CB 3.09Å; V60-V64 VanDerWaalsContact O-CG2 3.3Å; V60-V64 WeakPolarHBondContact O-CG2 3.25Å; V60-V64 PolarHBondContact O-N 3.05Å; T61-V64 PolarHBondContact O-N 2.88Å; F62-V64 PolarHBondContact O-N 3.43Å; V64-G68 PolarHBondContact O-N 3.21Å; V64-C342 HydrophobicContact CG1-CB 3.77Å
65	A	94.4	Very high	92.9	Very high	1 Å²	1	37.4 Å²	37.4	1%	0.008	23%	0.234	C	C	.	.	H	α-helix	trans	-64.2	-45.4	179.1	0	0	0	0	0	111.8	T61 F62 N69 A101	T61-A65 WeakPolarHBondContact O-CB 3.31Å; T61-A65 PolarHBondContact O-N 2.93Å; F62-A65 PolarHBondContact O-N 3.38Å; A65-N69 VanDerWaalsContact O-CB 3.3Å; A65-N69 WeakPolarHBondContact O-CB 3.34Å; A65-N69 PolarHBondContact O-N 2.77Å; A65-N69 PolarHBondContact O-ND2 3.44Å; A65-A101 HydrophobicContact CB-CB 4.05Å
66	V	95.8	Very high	92.6	Very high	27 Å²	27	35.8 Å²	35.8	16%	0.164	23%	0.226	C	C	.	.	H	α-helix	trans	-66.5	-51.5	179.1	171.9	0	0	0	0	110.9	F62 A63 S70 L98 A101 F102	F62-V66 HydrophobicContact CD2-CG2 4.05Å; F62-V66 HydrophobicContact CE1-CG2 4.21Å; F62-V66 HydrophobicContact CE2-CG2 3.69Å; F62-V66 HydrophobicContact CG-CG2 4.45Å; F62-V66 HydrophobicContact CZ-CG2 3.79Å; F62-V66 WeakPolarHBondContact O-CB 3.24Å; F62-V66 VanDerWaalsContact O-CG2 3.3Å; F62-V66 WeakPolarHBondContact O-CG2 3.48Å; F62-V66 PolarHBondContact O-N 3.42Å; A63-V66 PolarHBondContact O-N 3.29Å; V66-S70 WeakPolarHBondContact O-CB 3.4Å; V66-S70 PolarHBondContact O-N 2.95Å; V66-S70 PolarHBondContact O-OG 2.91Å; V66-L98 HydrophobicContact CB-CD2 4.49Å; V66-L98 HydrophobicContact CG2-CD2 4.41Å; V66-A101 HydrophobicContact CG2-CB 3.93Å; V66-F102 HydrophobicContact CG1-CE2 4.47Å; V66-F102 HydrophobicContact CG1-CZ 4.4Å; V66-F102 HydrophobicContact CG2-CE2 3.98Å; V66-F102 HydrophobicContact CG2-CZ 4.16Å
67	L	94.1	Very high	92.3	Very high	120 Å²	120	40.6 Å²	40.6	63%	0.628	24%	0.239	S	C	*	.	H	α-helix	trans	-62.4	-46.9	-178.8	-69.4	173.4	0	0	0	111.3	A63 S71	A63-L67 VanDerWaalsContact O-CB 3.27Å; A63-L67 WeakPolarHBondContact O-CB 3.36Å; A63-L67 WeakPolarHBondContact O-CG 3.34Å; A63-L67 PolarHBondContact O-N 3.31Å; L67-S71 VanDerWaalsContact O-CB 3.25Å; L67-S71 WeakPolarHBondContact O-CB 3.37Å; L67-S71 PolarHBondContact O-N 3.37Å; L67-S71 PolarHBondContact O-OG 3Å
68	G	92.9	Very high	92	Very high	17 Å²	17	43.7 Å²	43.7	18%	0.175	25%	0.246	C	C	.	.	H	α-helix	trans	-64.2	-51.6	-178.4	0	0	0	0	0	112.5	V64 S71 V72	V64-G68 PolarHBondContact O-N 3.21Å; G68-S71 PolarHBondContact O-N 3.4Å; G68-V72 WeakPolarHBondContact O-CG2 3.31Å; G68-V72 PolarHBondContact O-N 3.29Å
69	N	93.8	Very high	91.3	Very high	0 Å²	0	44.8 Å²	44.8	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-70.8	-34.8	-178	-72	-67.8	0	0	0	112.5	A65 S71 V72 L73 S94 L98 S341	A65-N69 VanDerWaalsContact O-CB 3.3Å; A65-N69 WeakPolarHBondContact O-CB 3.34Å; A65-N69 PolarHBondContact O-N 2.77Å; A65-N69 PolarHBondContact O-ND2 3.44Å; N69-S71 VanDerWaalsContact C-N 3.34Å; N69-V72 PolarHBondContact O-N 2.93Å; N69-L73 WeakPolarHBondContact O-CG 3.29Å; N69-L73 PolarHBondContact O-N 3.48Å; N69-S94 PolarHBondContact OD1-OG 3.16Å; N69-L98 HydrophobicContact CB-CD2 3.94Å; N69-L98 HydrophobicContact CB-CG 3.85Å; N69-S341 PolarHBondContact ND2-O 2.8Å; N69-S341 VanDerWaalsContact ND2-O 3.14Å
70	S	93.5	Very high	89.7	Confident	51 Å²	51	48.7 Å²	48.7	36%	0.357	28%	0.275	S	S	.	.	H	α-helix	trans	-65.2	-39	173	-56.9	0	0	0	0	111.7	V66 L73 L74	V66-S70 WeakPolarHBondContact O-CB 3.4Å; V66-S70 PolarHBondContact O-N 2.95Å; V66-S70 PolarHBondContact O-OG 2.91Å; S70-L73 PolarHBondContact O-N 3.25Å; S70-L74 WeakPolarHBondContact O-CB 3.24Å; S70-L74 PolarHBondContact O-N 3.27Å
71	S	90.7	Very high	87.9	Confident	30 Å²	30	54.8 Å²	54.8	21%	0.21	29%	0.287	C	S	.	.	H	α-helix	trans	-63.4	-41	175.7	-60.2	0	0	0	0	111.9	L67 G68 N69 L74 A75	L67-S71 VanDerWaalsContact O-CB 3.25Å; L67-S71 WeakPolarHBondContact O-CB 3.37Å; L67-S71 PolarHBondContact O-N 3.37Å; L67-S71 PolarHBondContact O-OG 3Å; G68-S71 PolarHBondContact O-N 3.4Å; N69-S71 VanDerWaalsContact C-N 3.34Å; S71-L74 PolarHBondContact O-N 3.01Å; S71-A75 WeakPolarHBondContact O-CB 3.46Å; S71-A75 PolarHBondContact O-N 2.93Å
72	V	90.9	Very high	86.2	Confident	12 Å²	12	64.2 Å²	64.2	7%	0.073	33%	0.328	C	S	.	.	H	α-helix	trans	-62.7	-45.9	174.3	173.1	0	0	0	0	111	G68 N69 L74 A75 L76 I90 S94 P345 Y348	G68-V72 WeakPolarHBondContact O-CG2 3.31Å; G68-V72 PolarHBondContact O-N 3.29Å; N69-V72 PolarHBondContact O-N 2.93Å; V72-L74 VanDerWaalsContact C-N 3.34Å; V72-L74 PolarHBondContact O-N 3.34Å; V72-A75 PolarHBondContact O-N 3.23Å; V72-L76 HydrophobicContact CG1-CD1 3.99Å; V72-L76 HydrophobicContact CG1-CG 4.41Å; V72-L76 WeakPolarHBondContact O-CB 3.45Å; V72-L76 VanDerWaalsContact O-CG 3.25Å; V72-L76 WeakPolarHBondContact O-CG 3.41Å; V72-L76 PolarHBondContact O-N 2.95Å; V72-I90 HydrophobicContact CG1-CG2 3.62Å; V72-S94 WeakPolarHBondContact CG1-OG 3.32Å; V72-P345 HydrophobicContact CG2-CB 3.94Å; V72-P345 HydrophobicContact CG2-CG 4.35Å; V72-Y348 HydrophobicContact CG1-CD2 4.09Å; V72-Y348 HydrophobicContact CG2-CD2 4.03Å
73	L	91.6	Very high	84.6	Confident	35 Å²	35	67.5 Å²	67.5	18%	0.183	35%	0.352	C	S	.	.	H	α-helix	trans	-61.5	-42.4	176.9	-71.9	174.8	0	0	0	112.1	N69 S70 L76 H77 R91 L95 L98	N69-L73 WeakPolarHBondContact O-CG 3.29Å; N69-L73 PolarHBondContact O-N 3.48Å; S70-L73 PolarHBondContact O-N 3.25Å; L73-L76 PolarHBondContact O-N 2.81Å; L73-H77 WeakPolarHBondContact O-CB 3.01Å; L73-H77 PolarHBondContact O-N 3.46Å; L73-R91 HydrophobicContact CD2-CB 4.31Å; L73-R91 HydrophobicContact CD2-CG 3.7Å; L73-L95 HydrophobicContact CD1-CD2 3.95Å; L73-L95 HydrophobicContact CD1-CG 4.43Å; L73-L95 HydrophobicContact CD2-CG 4.35Å; L73-L98 HydrophobicContact CD1-CD1 3.48Å; L73-L98 VanDerWaalsContact CD1-CD1 3.48Å
74	L	90	Very high	83.6	Confident	68 Å²	68	68.2 Å²	68.2	36%	0.356	35%	0.354	S	S	.	.	H	α-helix	trans	-64	-46.1	177.2	-177.6	60.3	0	0	0	111.7	S70 S71 V72 L76 H77 R78	S70-L74 WeakPolarHBondContact O-CB 3.24Å; S70-L74 PolarHBondContact O-N 3.27Å; S71-L74 PolarHBondContact O-N 3.01Å; V72-L74 VanDerWaalsContact C-N 3.34Å; V72-L74 PolarHBondContact O-N 3.34Å; L74-L76 PolarHBondContact O-N 2.89Å; L74-H77 PolarHBondContact O-N 3.44Å; L74-R78 HydrophobicContact CD1-CG 4.37Å; L74-R78 WeakPolarHBondContact O-CB 3.28Å; L74-R78 WeakPolarHBondContact O-CG 3.25Å; L74-R78 PolarHBondContact O-N 3.43Å
75	A	86.6	Confident	83	Confident	1 Å²	1	68.7 Å²	68.7	1%	0.008	35%	0.35	C	S	.	.	H	α-helix	trans	-58.4	-49.1	175.4	0	0	0	0	0	110.8	S71 V72 H77 R78 T79 D358 C359	S71-A75 WeakPolarHBondContact O-CB 3.46Å; S71-A75 PolarHBondContact O-N 2.93Å; V72-A75 PolarHBondContact O-N 3.23Å; A75-H77 VanDerWaalsContact C-N 3.27Å; A75-H77 PolarHBondContact O-N 3.35Å; A75-R78 PolarHBondContact O-N 3.48Å; A75-R78 VanDerWaalsContact O-N 3.09Å; A75-T79 PolarHBondContact O-N 3.22Å; A75-T79 PolarHBondContact O-OG1 2.97Å; A75-D358 HydrophobicContact CB-CB 4.17Å; A75-C359 HydrophobicContact CB-CB 4.39Å
76	L	87	Confident	82.5	Confident	6 Å²	6	69.2 Å²	69.2	3%	0.031	35%	0.352	C	S	.	.	H	α-helix	trans	-63.8	-28.9	177.6	-70.9	175.4	0	0	0	114	V72 L73 L74 H87 I90 R91 L355	V72-L76 HydrophobicContact CG1-CD1 3.99Å; V72-L76 HydrophobicContact CG1-CG 4.41Å; V72-L76 WeakPolarHBondContact O-CB 3.45Å; V72-L76 VanDerWaalsContact O-CG 3.25Å; V72-L76 WeakPolarHBondContact O-CG 3.41Å; V72-L76 PolarHBondContact O-N 2.95Å; L73-L76 PolarHBondContact O-N 2.81Å; L74-L76 PolarHBondContact O-N 2.89Å; L76-H87 HydrophobicContact CD2-CB 3.89Å; L76-I90 HydrophobicContact CD1-CB 4.07Å; L76-I90 HydrophobicContact CD1-CG2 3.72Å; L76-R91 HydrophobicContact CD1-CB 4.22Å; L76-L355 HydrophobicContact CD2-CD1 4.34Å; L76-L355 HydrophobicContact CD2-CD2 3.68Å; L76-L355 HydrophobicContact CG-CD2 4.38Å
77	H	86.6	Confident	82	Confident	156 Å²	156	69 Å²	69	72%	0.722	35%	0.35	S	S	*	.	H	α-helix	trans	-74.8	-36.1	174.2	-174.6	-85.5	0	0	0	111.4	L73 L74 A75	L73-H77 WeakPolarHBondContact O-CB 3.01Å; L73-H77 PolarHBondContact O-N 3.46Å; L74-H77 PolarHBondContact O-N 3.44Å; A75-H77 VanDerWaalsContact C-N 3.27Å; A75-H77 PolarHBondContact O-N 3.35Å
78	R	84.6	Confident	81.8	Confident	110 Å²	110	65.2 Å²	65.2	42%	0.415	33%	0.33	S	S	.	.	H	α-helix	trans	-81.7	-22.7	-178.9	-73.8	-173.6	175.9	150.3	-2	114.3	L74 A75 P80 S362	L74-R78 HydrophobicContact CD1-CG 4.37Å; L74-R78 WeakPolarHBondContact O-CB 3.28Å; L74-R78 WeakPolarHBondContact O-CG 3.25Å; L74-R78 PolarHBondContact O-N 3.43Å; A75-R78 PolarHBondContact O-N 3.48Å; A75-R78 VanDerWaalsContact O-N 3.09Å; R78-P80 WeakPolarHBondContact O-CD 3.37Å; R78-P80 WeakPolarHBondContact O-CG 3.49Å; R78-P80 VanDerWaalsContact O-N 3.1Å; R78-S362 PolarHBondContact NH1-O 2.95Å; R78-S362 PolarHBondContact NH1-OG 3.49Å
79	T	77.4	Confident	81.8	Confident	30 Å²	30	64.6 Å²	64.6	18%	0.184	32%	0.322	C	S	.	.			trans	-63.7	105.1	179	-51.7	0	0	0	0	111.3	A75 R81 D358	A75-T79 PolarHBondContact O-N 3.22Å; A75-T79 PolarHBondContact O-OG1 2.97Å; T79-R81 VanDerWaalsContact C-N 3.32Å; T79-R81 PolarHBondContact O-N 2.87Å; T79-R81 VanDerWaalsContact O-N 3.1Å; T79-D358 PolarHBondContact OG1-OD2 3.48Å
80	P	62.1	Low	81.7	Confident	123 Å²	123	64.6 Å²	64.6	80%	0.799	32%	0.322	S	S	*	.			trans	-80.6	12.2	-165.2	-12	28.4	0	0	0	116.5	R78	R78-P80 WeakPolarHBondContact O-CD 3.37Å; R78-P80 WeakPolarHBondContact O-CG 3.49Å; R78-P80 VanDerWaalsContact O-N 3.1Å
81	R	55.6	Low	81.6	Confident	222 Å²	222	66.1 Å²	66.1	84%	0.838	32%	0.32	S	S	*	.	S	Bend	trans	-142	118.5	-169.4	-73.4	-177.4	172	160.2	-3.3	113.5	T79	T79-R81 VanDerWaalsContact C-N 3.32Å; T79-R81 PolarHBondContact O-N 2.87Å; T79-R81 VanDerWaalsContact O-N 3.1Å
82	K	56.3	Low	81.8	Confident	203 Å²	203	67 Å²	67	88%	0.883	32%	0.321	S	S	*	.			trans	39.9	96.4	176.3	-68.4	-172.4	179.3	-179.1	0	114.2	S84	K82-S84 PolarHBondContact O-N 3.21Å
83	T	62.5	Low	82	Confident	110 Å²	110	66.5 Å²	66.5	68%	0.675	32%	0.318	S	S	*	.			trans	-53.3	100.1	169.3	46.5	0	0	0	0	110
84	S	74.6	Confident	82.1	Confident	59 Å²	59	64.8 Å²	64.8	41%	0.413	31%	0.309	S	S	.	.			trans	-61.6	147.6	172.9	176.6	0	0	0	0	108.2	K82 M86 H87 L88	K82-S84 PolarHBondContact O-N 3.21Å; S84-M86 PolarHBondContact O-N 3.45Å; S84-M86 PolarHBondContact OG-N 3.1Å; S84-H87 WeakPolarHBondContact O-CA 3.36Å; S84-H87 VanDerWaalsContact O-CB 3.32Å; S84-H87 WeakPolarHBondContact O-CB 3.47Å; S84-H87 PolarHBondContact O-N 2.92Å; S84-L88 PolarHBondContact O-N 3.34Å
85	R	82.5	Confident	82.4	Confident	62 Å²	62	65 Å²	65	23%	0.234	31%	0.31	C	S	.	.	H	α-helix	trans	-52	-31.4	171.5	-156.9	-168.2	-38.1	163	-1.4	111.8	L88 F89 D148 S167	R85-L88 WeakPolarHBondContact O-CB 3.42Å; R85-L88 PolarHBondContact O-N 2.87Å; R85-F89 HydrophobicContact CG-CE2 4.38Å; R85-F89 VanDerWaalsContact O-CD2 3.31Å; R85-F89 WeakPolarHBondContact O-CD2 3.44Å; R85-F89 PolarHBondContact O-N 3.48Å; R85-D148 IonicContact NH1-OD1 3.21Å; R85-D148 PolarHBondContact NH1-OD1 3.43Å; R85-D148 IonicContact NH1-OD2 3.88Å; R85-S167 WeakPolarHBondContact CD-OG 3.35Å; R85-S167 VanDerWaalsContact CG-OG 3.28Å; R85-S167 WeakPolarHBondContact CG-OG 3.48Å
86	M	83.1	Confident	82.9	Confident	11 Å²	11	65 Å²	65	5%	0.054	31%	0.31	C	S	.	.	H	α-helix	trans	-65.4	-41.3	173.7	-176	57.3	91.6	0	0	112.4	S84 L88 F89 I90 R149 T289 M292 T293	S84-M86 PolarHBondContact O-N 3.45Å; S84-M86 PolarHBondContact OG-N 3.1Å; M86-L88 PolarHBondContact O-N 3.36Å; M86-F89 PolarHBondContact O-N 3.35Å; M86-F89 VanDerWaalsContact O-N 3.1Å; M86-I90 HydrophobicContact CG-CD1 3.77Å; M86-I90 HydrophobicContact CG-CG1 4.15Å; M86-I90 WeakPolarHBondContact O-CG1 3.42Å; M86-I90 PolarHBondContact O-N 3.5Å; M86-I90 HydrophobicContact SD-CD1 4.38Å; M86-I90 HydrophobicContact SD-CG1 4.2Å; M86-R149 VanDerWaalsContact CE-NH1 3.31Å; M86-T289 VanDerWaalsContact CE-CB 3.44Å; M86-T289 HydrophobicContact CE-CG2 3.63Å; M86-M292 HydrophobicContact CE-CE 3.9Å; M86-M292 HydrophobicContact CG-CE 4.39Å; M86-M292 HydrophobicContact SD-CE 3.91Å; M86-T293 HydrophobicContact CE-CG2 4.25Å
87	H	86.6	Confident	83.3	Confident	24 Å²	24	64.7 Å²	64.7	11%	0.111	31%	0.308	C	S	.	.	H	α-helix	trans	-61.1	-32.4	178	-64.6	-177.1	0	0	0	111.4	L76 S84 R91 H354	L76-H87 HydrophobicContact CD2-CB 3.89Å; S84-H87 WeakPolarHBondContact O-CA 3.36Å; S84-H87 VanDerWaalsContact O-CB 3.32Å; S84-H87 WeakPolarHBondContact O-CB 3.47Å; S84-H87 PolarHBondContact O-N 2.92Å; H87-R91 VanDerWaalsContact O-CB 3.28Å; H87-R91 WeakPolarHBondContact O-CB 3.5Å; H87-R91 PolarHBondContact O-N 3.1Å; H87-H354 AromaticContact CE1-CE1 3.99Å; H87-H354 AromaticContact CE1-NE2 3.47Å; H87-H354 PolarHBondContact CE1-NE2 3.48Å; H87-H354 AromaticContact NE2-CE1 3.49Å; H87-H354 PolarHBondContact NE2-CE1 2.81Å; H87-H354 AromaticContact NE2-NE2 3.41Å; H87-H354 PolarHBondContact NE2-NE2 3.08Å
88	L	90	Very high	83.7	Confident	40 Å²	40	58.3 Å²	58.3	21%	0.209	28%	0.28	C	S	.	.	H	α-helix	trans	-64.6	-47.1	173.4	-176	65.5	0	0	0	111.8	S84 R85 M86 R91 H92 R168 I171	S84-L88 PolarHBondContact O-N 3.34Å; R85-L88 WeakPolarHBondContact O-CB 3.42Å; R85-L88 PolarHBondContact O-N 2.87Å; M86-L88 PolarHBondContact O-N 3.36Å; L88-R91 PolarHBondContact O-N 3.48Å; L88-H92 PolarHBondContact O-CD2 2.9Å; L88-H92 PolarHBondContact O-N 3.46Å; L88-H92 VanDerWaalsContact O-N 3.12Å; L88-R168 HydrophobicContact CD2-CG 3.92Å; L88-I171 HydrophobicContact CD2-CD1 3.83Å; L88-I171 HydrophobicContact CG-CD1 3.71Å
89	F	91.6	Very high	84.2	Confident	3 Å²	3	53.6 Å²	53.6	1%	0.013	26%	0.264	C	S	.	.	H	α-helix	trans	-63.5	-45.5	176.4	-77	-70.6	0	0	0	112.2	R85 M86 R91 H92 L93 V144 M145 D148 S167 I171	R85-F89 HydrophobicContact CG-CE2 4.38Å; R85-F89 VanDerWaalsContact O-CD2 3.31Å; R85-F89 WeakPolarHBondContact O-CD2 3.44Å; R85-F89 PolarHBondContact O-N 3.48Å; M86-F89 PolarHBondContact O-N 3.35Å; M86-F89 VanDerWaalsContact O-N 3.1Å; F89-R91 VanDerWaalsContact C-N 3.28Å; F89-R91 PolarHBondContact O-N 3.07Å; F89-H92 PolarHBondContact O-N 2.95Å; F89-L93 WeakPolarHBondContact O-CB 3.22Å; F89-L93 PolarHBondContact O-N 3.49Å; F89-V144 HydrophobicContact CD1-CG2 4.39Å; F89-V144 HydrophobicContact CE1-CB 4.35Å; F89-V144 HydrophobicContact CE1-CG2 3.95Å; F89-M145 HydrophobicContact CB-CB 4.47Å; F89-M145 HydrophobicContact CB-CG 4.2Å; F89-M145 HydrophobicContact CB-SD 4.42Å; F89-M145 HydrophobicContact CD1-CB 4.09Å; F89-M145 HydrophobicContact CG-CB 4.36Å; F89-M145 HydrophobicContact CG-CG 4.38Å; F89-D148 HydrophobicContact CE2-CB 3.59Å; F89-D148 VanDerWaalsContact CE2-CG 3.5Å; F89-D148 HydrophobicContact CZ-CB 3.59Å; F89-S167 WeakPolarHBondContact CE2-OG 3.38Å; F89-I171 HydrophobicContact CD1-CD1 3.98Å; F89-I171 HydrophobicContact CD1-CG1 3.98Å; F89-I171 HydrophobicContact CE1-CD1 3.97Å; F89-I171 HydrophobicContact CE1-CG1 3.73Å
90	I	91	Very high	85	Confident	0 Å²	0	52.4 Å²	52.4	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-59.2	-42.8	177.7	-62.9	172.2	0	0	0	110.1	V72 L76 M86 H92 L93 S94 M292 Y348 L355	V72-I90 HydrophobicContact CG1-CG2 3.62Å; L76-I90 HydrophobicContact CD1-CB 4.07Å; L76-I90 HydrophobicContact CD1-CG2 3.72Å; M86-I90 HydrophobicContact CG-CD1 3.77Å; M86-I90 HydrophobicContact CG-CG1 4.15Å; M86-I90 WeakPolarHBondContact O-CG1 3.42Å; M86-I90 PolarHBondContact O-N 3.5Å; M86-I90 HydrophobicContact SD-CD1 4.38Å; M86-I90 HydrophobicContact SD-CG1 4.2Å; I90-H92 PolarHBondContact O-N 3.36Å; I90-L93 PolarHBondContact O-N 2.95Å; I90-S94 WeakPolarHBondContact O-CB 3.31Å; I90-S94 PolarHBondContact O-N 2.91Å; I90-S94 PolarHBondContact O-OG 2.95Å; I90-M292 HydrophobicContact CD1-CE 4.22Å; I90-M292 HydrophobicContact CG1-CE 4.47Å; I90-Y348 HydrophobicContact CB-CE1 4.48Å; I90-Y348 HydrophobicContact CD1-CD1 4.05Å; I90-Y348 HydrophobicContact CD1-CE1 4.21Å; I90-Y348 HydrophobicContact CG1-CD1 4.15Å; I90-Y348 HydrophobicContact CG1-CE1 3.81Å; I90-Y348 HydrophobicContact CG2-CD1 4.18Å; I90-Y348 HydrophobicContact CG2-CD2 3.98Å; I90-Y348 HydrophobicContact CG2-CE1 4.04Å; I90-Y348 HydrophobicContact CG2-CE2 3.84Å; I90-Y348 HydrophobicContact CG2-CG 4.17Å; I90-L355 HydrophobicContact CD1-CD1 4.41Å
91	R	92.7	Very high	86.6	Confident	84 Å²	84	46.5 Å²	46.5	32%	0.317	22%	0.218	S	C	.	.	H	α-helix	trans	-58.1	-50.4	176.3	-178.3	-177.9	-63.2	172	-1.7	112.1	L73 L76 H87 L88 F89 L93 S94 L95	L73-R91 HydrophobicContact CD2-CB 4.31Å; L73-R91 HydrophobicContact CD2-CG 3.7Å; L76-R91 HydrophobicContact CD1-CB 4.22Å; H87-R91 VanDerWaalsContact O-CB 3.28Å; H87-R91 WeakPolarHBondContact O-CB 3.5Å; H87-R91 PolarHBondContact O-N 3.1Å; L88-R91 PolarHBondContact O-N 3.48Å; F89-R91 VanDerWaalsContact C-N 3.28Å; F89-R91 PolarHBondContact O-N 3.07Å; R91-L93 VanDerWaalsContact C-N 3.35Å; R91-S94 PolarHBondContact O-N 3.17Å; R91-L95 HydrophobicContact CG-CD1 4.38Å; R91-L95 WeakPolarHBondContact O-CG 3.45Å; R91-L95 PolarHBondContact O-N 3.31Å
92	H	95.3	Very high	88.5	Confident	47 Å²	47	40.3 Å²	40.3	22%	0.218	20%	0.198	C	C	.	.	H	α-helix	trans	-70.4	-31.2	-178.8	-79.9	-81.7	0	0	0	113.2	L88 F89 I90 L95 A96 M141 I171 W175	L88-H92 PolarHBondContact O-CD2 2.9Å; L88-H92 PolarHBondContact O-N 3.46Å; L88-H92 VanDerWaalsContact O-N 3.12Å; F89-H92 PolarHBondContact O-N 2.95Å; I90-H92 PolarHBondContact O-N 3.36Å; H92-L95 PolarHBondContact O-N 3.39Å; H92-A96 WeakPolarHBondContact O-CB 3.21Å; H92-A96 PolarHBondContact O-N 3.49Å; H92-M141 HydrophobicContact CB-SD 3.89Å; H92-I171 HydrophobicContact CB-CG2 4.16Å; H92-W175 AromaticContact ND1-NE1 3.34Å; H92-W175 PolarHBondContact ND1-NE1 2.69Å
93	L	94	Very high	90.3	Very high	2 Å²	2	34.6 Å²	34.6	1%	0.01	17%	0.173	C	C	.	.	H	α-helix	trans	-67.1	-45.5	173.1	-176	47.2	0	0	0	111	F89 I90 R91 L95 A96 D97 M141 L142 M145 Y348	F89-L93 WeakPolarHBondContact O-CB 3.22Å; F89-L93 PolarHBondContact O-N 3.49Å; I90-L93 PolarHBondContact O-N 2.95Å; R91-L93 VanDerWaalsContact C-N 3.35Å; L93-L95 VanDerWaalsContact C-N 3.3Å; L93-L95 PolarHBondContact O-N 2.85Å; L93-A96 WeakPolarHBondContact O-CB 3.35Å; L93-A96 PolarHBondContact O-N 3.2Å; L93-A96 VanDerWaalsContact O-N 3.09Å; L93-D97 VanDerWaalsContact O-CG 3.32Å; L93-D97 PolarHBondContact O-N 3.14Å; L93-M141 HydrophobicContact CD1-CB 3.95Å; L93-L142 HydrophobicContact CD1-CD2 4.11Å; L93-L142 HydrophobicContact CD1-CG 4.43Å; L93-L142 HydrophobicContact CD2-CD2 3.67Å; L93-M145 HydrophobicContact CD2-CE 3.62Å; L93-M145 HydrophobicContact CD2-SD 4.02Å; L93-Y348 WeakPolarHBondContact CD2-OH 3.46Å; L93-Y348 WeakPolarHBondContact CG-OH 3.27Å
94	S	95	Very high	91.7	Very high	0 Å²	0	30.8 Å²	30.8	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-61.4	-35.2	172.8	-67	0	0	0	0	113.2	N69 V72 I90 R91 L98	N69-S94 PolarHBondContact OD1-OG 3.16Å; V72-S94 WeakPolarHBondContact CG1-OG 3.32Å; I90-S94 WeakPolarHBondContact O-CB 3.31Å; I90-S94 PolarHBondContact O-N 2.91Å; I90-S94 PolarHBondContact O-OG 2.95Å; R91-S94 PolarHBondContact O-N 3.17Å; S94-L98 WeakPolarHBondContact O-CB 3.3Å; S94-L98 VanDerWaalsContact O-CG 3.31Å; S94-L98 WeakPolarHBondContact O-CG 3.46Å; S94-L98 PolarHBondContact O-N 3.45Å
95	L	96.1	Very high	92.5	Very high	72 Å²	72	28.1 Å²	28.1	38%	0.377	13%	0.129	S	C	.	.	H	α-helix	trans	-66.5	-39.5	172.5	-72.3	170.8	0	0	0	112.2	L73 R91 H92 L93 L98 A99 W175	L73-L95 HydrophobicContact CD1-CD2 3.95Å; L73-L95 HydrophobicContact CD1-CG 4.43Å; L73-L95 HydrophobicContact CD2-CG 4.35Å; R91-L95 HydrophobicContact CG-CD1 4.38Å; R91-L95 WeakPolarHBondContact O-CG 3.45Å; R91-L95 PolarHBondContact O-N 3.31Å; H92-L95 PolarHBondContact O-N 3.39Å; L93-L95 VanDerWaalsContact C-N 3.3Å; L93-L95 PolarHBondContact O-N 2.85Å; L95-L98 PolarHBondContact O-N 2.81Å; L95-A99 PolarHBondContact O-N 3.36Å; L95-W175 HydrophobicContact CB-CZ2 4.38Å
96	A	96.2	Very high	93.1	Very high	0 Å²	0	27.5 Å²	27.5	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-66.7	-39.8	175.6	0	0	0	0	0	111.8	H92 L93 A99 V100 A137 M141 W175	H92-A96 WeakPolarHBondContact O-CB 3.21Å; H92-A96 PolarHBondContact O-N 3.49Å; L93-A96 WeakPolarHBondContact O-CB 3.35Å; L93-A96 PolarHBondContact O-N 3.2Å; L93-A96 VanDerWaalsContact O-N 3.09Å; A96-A99 WeakPolarHBondContact O-CB 3.31Å; A96-A99 PolarHBondContact O-N 3.35Å; A96-V100 WeakPolarHBondContact O-CG2 3.34Å; A96-V100 PolarHBondContact O-N 3Å; A96-A137 HydrophobicContact CB-CB 4.11Å; A96-M141 HydrophobicContact CB-CG 4.06Å; A96-W175 HydrophobicContact CB-CH2 4.2Å; A96-W175 HydrophobicContact CB-CZ2 4.34Å
97	D	95.3	Very high	93.5	Very high	0 Å²	0	28.4 Å²	28.4	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-69.8	-33.5	176.7	-63.4	-29.9	0	0	0	112.3	L93 V100 A101 S138 N344	L93-D97 VanDerWaalsContact O-CG 3.32Å; L93-D97 PolarHBondContact O-N 3.14Å; D97-V100 WeakPolarHBondContact O-CB 3.38Å; D97-V100 PolarHBondContact O-N 2.89Å; D97-A101 PolarHBondContact O-N 3.47Å; D97-S138 PolarHBondContact OD1-OG 3.12Å; D97-N344 PolarHBondContact OD2-ND2 3.39Å
98	L	95.7	Very high	93.7	Very high	23 Å²	23	29 Å²	29	12%	0.12	14%	0.139	C	C	.	.	H	α-helix	trans	-65.9	-39.1	168.4	-74.7	175.7	0	0	0	111.6	V66 N69 L73 S94 L95 V100 A101 F102	V66-L98 HydrophobicContact CB-CD2 4.49Å; V66-L98 HydrophobicContact CG2-CD2 4.41Å; N69-L98 HydrophobicContact CB-CD2 3.94Å; N69-L98 HydrophobicContact CB-CG 3.85Å; L73-L98 HydrophobicContact CD1-CD1 3.48Å; L73-L98 VanDerWaalsContact CD1-CD1 3.48Å; S94-L98 WeakPolarHBondContact O-CB 3.3Å; S94-L98 VanDerWaalsContact O-CG 3.31Å; S94-L98 WeakPolarHBondContact O-CG 3.46Å; S94-L98 PolarHBondContact O-N 3.45Å; L95-L98 PolarHBondContact O-N 2.81Å; L98-V100 VanDerWaalsContact C-N 3.3Å; L98-V100 PolarHBondContact O-N 2.97Å; L98-A101 PolarHBondContact O-N 3.17Å; L98-A101 VanDerWaalsContact O-N 3.15Å; L98-F102 HydrophobicContact CD2-CE2 4.32Å; L98-F102 WeakPolarHBondContact O-CD2 3.14Å; L98-F102 PolarHBondContact O-N 2.97Å
99	A	95.2	Very high	93.7	Very high	11 Å²	11	28.4 Å²	28.4	9%	0.091	14%	0.136	C	C	.	.	H	α-helix	trans	-60.9	-40.9	173	0	0	0	0	0	111.1	L95 A96 F103	L95-A99 PolarHBondContact O-N 3.36Å; A96-A99 WeakPolarHBondContact O-CB 3.31Å; A96-A99 PolarHBondContact O-N 3.35Å; A99-F103 HydrophobicContact CB-CD2 4Å; A99-F103 HydrophobicContact CB-CE2 4.34Å; A99-F103 WeakPolarHBondContact O-CA 3.35Å; A99-F103 WeakPolarHBondContact O-CB 3.34Å; A99-F103 WeakPolarHBondContact O-CD2 3.19Å; A99-F103 PolarHBondContact O-N 2.9Å
100	V	94.7	Very high	93.7	Very high	4 Å²	4	31 Å²	31	2%	0.024	15%	0.154	C	C	.	.	I	π-helix	trans	-60.1	-47.1	170.4	169.5	0	0	0	0	111	A96 D97 L98 F102 Q104 V105 G134 S341	A96-V100 WeakPolarHBondContact O-CG2 3.34Å; A96-V100 PolarHBondContact O-N 3Å; D97-V100 WeakPolarHBondContact O-CB 3.38Å; D97-V100 PolarHBondContact O-N 2.89Å; L98-V100 VanDerWaalsContact C-N 3.3Å; L98-V100 PolarHBondContact O-N 2.97Å; V100-F102 PolarHBondContact O-N 3.37Å; V100-Q104 HydrophobicContact CG1-CB 4.26Å; V100-Q104 CarbonylContact O-C 3.58Å; V100-Q104 VanDerWaalsContact O-CA 3.26Å; V100-Q104 WeakPolarHBondContact O-CA 3.36Å; V100-Q104 WeakPolarHBondContact O-CB 3.39Å; V100-Q104 PolarHBondContact O-N 3.27Å; V100-V105 HydrophobicContact CG1-CG2 4.34Å; V100-V105 PolarHBondContact O-N 2.98Å; V100-G134 VanDerWaalsContact CG2-C 3.48Å; V100-G134 VanDerWaalsContact CG2-O 3.3Å; V100-G134 WeakPolarHBondContact CG2-O 3.41Å; V100-S341 WeakPolarHBondContact CG1-OG 3.41Å
101	A	94.7	Very high	93.7	Very high	0 Å²	0	32 Å²	32	0%	0	16%	0.158	C	C	.	.	I	π-helix	trans	-60.7	-50.1	179.6	0	0	0	0	0	112.5	F62 A65 V66 D97 L98 V105 L106	F62-A101 HydrophobicContact CD2-CB 4.14Å; F62-A101 WeakPolarHBondContact CD2-O 3.21Å; F62-A101 HydrophobicContact CE2-CB 4.33Å; F62-A101 WeakPolarHBondContact CE2-O 3.48Å; A65-A101 HydrophobicContact CB-CB 4.05Å; V66-A101 HydrophobicContact CG2-CB 3.93Å; D97-A101 PolarHBondContact O-N 3.47Å; L98-A101 PolarHBondContact O-N 3.17Å; L98-A101 VanDerWaalsContact O-N 3.15Å; A101-V105 WeakPolarHBondContact O-CB 3.5Å; A101-V105 PolarHBondContact O-N 2.87Å; A101-L106 WeakPolarHBondContact O-CB 3.44Å; A101-L106 PolarHBondContact O-N 2.92Å
102	F	95.5	Very high	93.4	Very high	92 Å²	92	28.3 Å²	28.3	40%	0.404	14%	0.144	S	C	.	.	I	π-helix	trans	-79.8	-32.4	-174.9	-81.2	-75.7	0	0	0	114.6	F62 V66 L98 V100 L106 P107	F62-F102 HydrophobicContact CE2-CD1 4.18Å; F62-F102 HydrophobicContact CE2-CE1 4.31Å; F62-F102 HydrophobicContact CE2-CG 4.49Å; F62-F102 HydrophobicContact CZ-CD1 4.21Å; F62-F102 AromaticContact CZ-CE1 3.93Å; F62-F102 HydrophobicContact CZ-CE1 3.93Å; F62-F102 HydrophobicContact CZ-CZ 4.39Å; V66-F102 HydrophobicContact CG1-CE2 4.47Å; V66-F102 HydrophobicContact CG1-CZ 4.4Å; V66-F102 HydrophobicContact CG2-CE2 3.98Å; V66-F102 HydrophobicContact CG2-CZ 4.16Å; L98-F102 HydrophobicContact CD2-CE2 4.32Å; L98-F102 WeakPolarHBondContact O-CD2 3.14Å; L98-F102 PolarHBondContact O-N 2.97Å; V100-F102 PolarHBondContact O-N 3.37Å; F102-L106 HydrophobicContact CD1-CD2 4.11Å; F102-P107 VanDerWaalsContact O-CD 3.28Å; F102-P107 WeakPolarHBondContact O-CD 3.46Å
103	F	93.5	Very high	93.2	Very high	82 Å²	82	30.5 Å²	30.5	36%	0.36	16%	0.157	S	C	.	.	I	π-helix	trans	-105.2	-21.8	-175.7	-58.3	-49.4	0	0	0	113.7	A99 P107 L130 Q131	A99-F103 HydrophobicContact CB-CD2 4Å; A99-F103 HydrophobicContact CB-CE2 4.34Å; A99-F103 WeakPolarHBondContact O-CA 3.35Å; A99-F103 WeakPolarHBondContact O-CB 3.34Å; A99-F103 WeakPolarHBondContact O-CD2 3.19Å; A99-F103 PolarHBondContact O-N 2.9Å; F103-P107 VanDerWaalsContact C-CD 3.5Å; F103-P107 WeakPolarHBondContact O-CD 3.44Å; F103-P107 VanDerWaalsContact O-CG 3.27Å; F103-P107 WeakPolarHBondContact O-CG 3.06Å; F103-L130 HydrophobicContact CB-CB 3.73Å; F103-L130 HydrophobicContact CD1-CB 4.16Å; F103-L130 HydrophobicContact CD1-CD1 3.82Å; F103-L130 HydrophobicContact CD2-CB 4.35Å; F103-L130 HydrophobicContact CE1-CD1 3.95Å; F103-L130 HydrophobicContact CG-CB 3.84Å; F103-L130 HydrophobicContact CG-CD1 4.28Å; F103-L130 HydrophobicContact CG-CG 4.5Å; F103-L130 HydrophobicContact CZ-CD1 4.49Å; F103-Q131 WeakPolarHBondContact O-CG 3.19Å
104	Q	92.1	Very high	93	Very high	30 Å²	30	32.1 Å²	32.1	14%	0.14	17%	0.167	C	C	.	.	I	π-helix	trans	-102.7	-60.9	176.6	-170	-170	-23.9	0	0	112.5	V100 Q108	V100-Q104 HydrophobicContact CG1-CB 4.26Å; V100-Q104 CarbonylContact O-C 3.58Å; V100-Q104 VanDerWaalsContact O-CA 3.26Å; V100-Q104 WeakPolarHBondContact O-CA 3.36Å; V100-Q104 WeakPolarHBondContact O-CB 3.39Å; V100-Q104 PolarHBondContact O-N 3.27Å; Q104-Q108 VanDerWaalsContact O-CB 3.22Å; Q104-Q108 WeakPolarHBondContact O-CB 3.11Å; Q104-Q108 PolarHBondContact O-N 3.05Å
105	V	92.5	Very high	92.4	Very high	4 Å²	4	34.9 Å²	34.9	2%	0.024	18%	0.177	C	C	.	.	I	π-helix	trans	-69.8	-48	-172.6	-177.1	0	0	0	0	111	L58 F62 V100 A101 Q108 M109	L58-V105 HydrophobicContact CB-CG1 4.36Å; L58-V105 HydrophobicContact CD2-CG1 3.99Å; F62-V105 HydrophobicContact CB-CG1 3.92Å; V100-V105 HydrophobicContact CG1-CG2 4.34Å; V100-V105 PolarHBondContact O-N 2.98Å; A101-V105 WeakPolarHBondContact O-CB 3.5Å; A101-V105 PolarHBondContact O-N 2.87Å; V105-Q108 PolarHBondContact O-N 3.31Å; V105-M109 WeakPolarHBondContact O-CB 3.24Å; V105-M109 PolarHBondContact O-N 3.49Å
106	L	93.6	Very high	91.9	Very high	49 Å²	49	33.4 Å²	33.4	26%	0.257	17%	0.167	S	C	.	.	H	α-helix	trans	-62.9	-49.7	-178.5	172.6	65.9	0	0	0	112.8	F62 A101 F102 Q108 M109 C110	F62-L106 HydrophobicContact CD2-CB 4.01Å; F62-L106 HydrophobicContact CE2-CB 3.74Å; F62-L106 HydrophobicContact CE2-CD2 4.29Å; F62-L106 HydrophobicContact CE2-CG 4.43Å; F62-L106 HydrophobicContact CZ-CB 4.39Å; F62-L106 HydrophobicContact CZ-CD1 4.49Å; F62-L106 HydrophobicContact CZ-CD2 4.26Å; A101-L106 WeakPolarHBondContact O-CB 3.44Å; A101-L106 PolarHBondContact O-N 2.92Å; F102-L106 HydrophobicContact CD1-CD2 4.11Å; L106-Q108 VanDerWaalsContact C-N 3.3Å; L106-Q108 PolarHBondContact O-N 2.82Å; L106-M109 HydrophobicContact CD1-CE 3.72Å; L106-M109 PolarHBondContact O-N 2.95Å; L106-C110 PolarHBondContact O-N 3.27Å; L106-C110 PolarHBondContact O-SG 3.41Å; L106-C110 VanDerWaalsContact O-SG 3.34Å
107	P	91.9	Very high	91.6	Very high	30 Å²	30	34.6 Å²	34.6	20%	0.195	17%	0.172	C	C	.	.	H	α-helix	trans	-66.6	-31.3	178.1	-26.1	39.7	0	0	0	113	F102 F103 W111 V127	F102-P107 VanDerWaalsContact O-CD 3.28Å; F102-P107 WeakPolarHBondContact O-CD 3.46Å; F103-P107 VanDerWaalsContact C-CD 3.5Å; F103-P107 WeakPolarHBondContact O-CD 3.44Å; F103-P107 VanDerWaalsContact O-CG 3.27Å; F103-P107 WeakPolarHBondContact O-CG 3.06Å; P107-W111 WeakPolarHBondContact O-CB 3.27Å; P107-W111 PolarHBondContact O-N 2.82Å; P107-V127 HydrophobicContact CB-CG1 3.72Å; P107-V127 HydrophobicContact CG-CG1 4.33Å
108	Q	90.2	Very high	91.3	Very high	35 Å²	35	43.9 Å²	43.9	16%	0.164	21%	0.207	C	C	.	.	H	α-helix	trans	-64.3	-48.8	171.8	-177.7	61.9	38.2	0	0	110.7	L58 Q104 V105 L106 C110 W111 D112	L58-Q108 HydrophobicContact CD1-CG 3.91Å; Q104-Q108 VanDerWaalsContact O-CB 3.22Å; Q104-Q108 WeakPolarHBondContact O-CB 3.11Å; Q104-Q108 PolarHBondContact O-N 3.05Å; V105-Q108 PolarHBondContact O-N 3.31Å; L106-Q108 VanDerWaalsContact C-N 3.3Å; L106-Q108 PolarHBondContact O-N 2.82Å; Q108-C110 VanDerWaalsContact C-N 3.34Å; Q108-C110 PolarHBondContact O-N 3.41Å; Q108-W111 WeakPolarHBondContact O-CA 3.5Å; Q108-W111 VanDerWaalsContact O-CB 3.25Å; Q108-W111 WeakPolarHBondContact O-CB 3.23Å; Q108-W111 PolarHBondContact O-N 3.46Å; Q108-D112 PolarHBondContact NE2-OD1 2.82Å; Q108-D112 PolarHBondContact NE2-OD2 2.85Å; Q108-D112 VanDerWaalsContact NE2-OD2 3.11Å; Q108-D112 PolarHBondContact O-N 3.04Å; Q108-D112 VanDerWaalsContact O-OD2 3.11Å
109	M	90.9	Very high	90.9	Very high	29 Å²	29	44 Å²	44	14%	0.143	21%	0.214	C	C	.	.	H	α-helix	trans	-59	-44.3	176.1	-174.4	-177	72.1	0	0	112	L58 A59 V105 L106 W111 D112 I113	L58-M109 HydrophobicContact CB-CB 4.05Å; L58-M109 HydrophobicContact CB-CG 4.18Å; L58-M109 HydrophobicContact CD1-CB 4.24Å; A59-M109 VanDerWaalsContact CA-SD 3.59Å; A59-M109 HydrophobicContact CB-SD 3.76Å; V105-M109 WeakPolarHBondContact O-CB 3.24Å; V105-M109 PolarHBondContact O-N 3.49Å; L106-M109 HydrophobicContact CD1-CE 3.72Å; L106-M109 PolarHBondContact O-N 2.95Å; M109-W111 VanDerWaalsContact C-N 3.29Å; M109-W111 PolarHBondContact O-N 3.1Å; M109-D112 PolarHBondContact O-N 3.28Å; M109-I113 HydrophobicContact CG-CD1 4.09Å; M109-I113 VanDerWaalsContact O-CG1 3.28Å; M109-I113 WeakPolarHBondContact O-CG1 3.28Å; M109-I113 PolarHBondContact O-N 3.03Å
110	C	92.6	Very high	90.8	Very high	58 Å²	58	46.6 Å²	46.6	39%	0.392	23%	0.23	S	C	.	.	H	α-helix	trans	-59.4	-42	174.7	-70.5	0	0	0	0	111.5	L106 Q108 I113 T114	L106-C110 PolarHBondContact O-N 3.27Å; L106-C110 PolarHBondContact O-SG 3.41Å; L106-C110 VanDerWaalsContact O-SG 3.34Å; Q108-C110 VanDerWaalsContact C-N 3.34Å; Q108-C110 PolarHBondContact O-N 3.41Å; C110-I113 PolarHBondContact O-N 3.17Å; C110-T114 WeakPolarHBondContact O-CG2 3.46Å; C110-T114 PolarHBondContact O-N 3.02Å; C110-T114 PolarHBondContact O-OG1 2.95Å
111	W	89.2	Confident	90.8	Very high	21 Å²	21	49.1 Å²	49.1	8%	0.08	24%	0.243	C	C	.	.	H	α-helix	trans	-61.1	-46	176.3	-167.6	-62.4	0	0	0	112.1	P107 Q108 M109 I113 T114 Y115 F117 D202 C203	P107-W111 WeakPolarHBondContact O-CB 3.27Å; P107-W111 PolarHBondContact O-N 2.82Å; Q108-W111 WeakPolarHBondContact O-CA 3.5Å; Q108-W111 VanDerWaalsContact O-CB 3.25Å; Q108-W111 WeakPolarHBondContact O-CB 3.23Å; Q108-W111 PolarHBondContact O-N 3.46Å; M109-W111 VanDerWaalsContact C-N 3.29Å; M109-W111 PolarHBondContact O-N 3.1Å; W111-I113 VanDerWaalsContact C-N 3.29Å; W111-I113 PolarHBondContact O-N 2.91Å; W111-T114 PolarHBondContact O-N 3.49Å; W111-Y115 WeakPolarHBondContact O-CA 3.3Å; W111-Y115 PolarHBondContact O-N 3.38Å; W111-F117 HydrophobicContact CE3-CB 3.96Å; W111-F117 AromaticContact CE3-CD2 3.6Å; W111-F117 HydrophobicContact CE3-CD2 3.6Å; W111-F117 HydrophobicContact CE3-CG 4.23Å; W111-F117 HydrophobicContact CH2-CB 3.66Å; W111-F117 HydrophobicContact CH2-CD2 4.41Å; W111-F117 HydrophobicContact CH2-CG 4.34Å; W111-F117 HydrophobicContact CZ2-CB 4.26Å; W111-F117 HydrophobicContact CZ3-CB 3.5Å; W111-F117 AromaticContact CZ3-CD2 3.42Å; W111-F117 HydrophobicContact CZ3-CD2 3.42Å; W111-F117 VanDerWaalsContact CZ3-CD2 3.42Å; W111-F117 HydrophobicContact CZ3-CE2 4.4Å; W111-F117 AromaticContact CZ3-CG 3.76Å; W111-F117 HydrophobicContact CZ3-CG 3.76Å; W111-D202 VanDerWaalsContact CH2-OD1 3.24Å; W111-D202 WeakPolarHBondContact CH2-OD1 3.3Å; W111-D202 VanDerWaalsContact CZ2-CG 3.44Å; W111-D202 WeakPolarHBondContact CZ2-OD1 3.49Å; W111-D202 WeakPolarHBondContact CZ2-OD2 2.95Å; W111-C203 HydrophobicContact CH2-CB 3.48Å; W111-C203 VanDerWaalsContact CH2-CB 3.48Å; W111-C203 WeakPolarHBondContact CH2-O 3.37Å; W111-C203 HydrophobicContact CZ3-CB 3.69Å
112	D	86.6	Confident	90.8	Very high	5 Å²	5	57.1 Å²	57.1	3%	0.027	27%	0.273	C	S	.	.	H	α-helix	trans	-66.6	-33.8	-178.7	-62.6	-35.3	0	0	0	111.4	R2 R46 I55 L58 Q108 M109	R2-D112 IonicContact NH2-OD1 2.76Å; R2-D112 PolarHBondContact NH2-OD1 3.39Å; R46-D112 PolarHBondContact NH1-O 3.26Å; I55-D112 HydrophobicContact CD1-CB 4.41Å; I55-D112 HydrophobicContact CG1-CB 3.8Å; L58-D112 WeakPolarHBondContact CD1-OD2 3.22Å; Q108-D112 PolarHBondContact NE2-OD1 2.82Å; Q108-D112 PolarHBondContact NE2-OD2 2.85Å; Q108-D112 VanDerWaalsContact NE2-OD2 3.11Å; Q108-D112 PolarHBondContact O-N 3.04Å; Q108-D112 VanDerWaalsContact O-OD2 3.11Å; M109-D112 PolarHBondContact O-N 3.28Å
113	I	91	Very high	90.7	Very high	94 Å²	94	55.3 Å²	55.3	48%	0.482	27%	0.268	S	S	.	.	H	α-helix	trans	-68.5	-50.3	172.4	-67.3	165.6	0	0	0	111.5	I55 M109 C110 W111 Y115	I55-I113 HydrophobicContact CD1-CG1 3.89Å; I55-I113 HydrophobicContact CG1-CG1 4.04Å; I55-I113 HydrophobicContact CG2-CD1 4.21Å; I55-I113 HydrophobicContact CG2-CG1 3.9Å; M109-I113 HydrophobicContact CG-CD1 4.09Å; M109-I113 VanDerWaalsContact O-CG1 3.28Å; M109-I113 WeakPolarHBondContact O-CG1 3.28Å; M109-I113 PolarHBondContact O-N 3.03Å; C110-I113 PolarHBondContact O-N 3.17Å; W111-I113 VanDerWaalsContact C-N 3.29Å; W111-I113 PolarHBondContact O-N 2.91Å; I113-Y115 VanDerWaalsContact C-N 3.28Å; I113-Y115 PolarHBondContact O-N 3.35Å
114	T	89.8	Confident	90.8	Very high	36 Å²	36	51.4 Å²	51.4	22%	0.221	25%	0.251	C	S	.	.	H	α-helix	trans	-81.8	-7.7	-173.4	58.6	0	0	0	0	113.6	C110 W111 R116	C110-T114 WeakPolarHBondContact O-CG2 3.46Å; C110-T114 PolarHBondContact O-N 3.02Å; C110-T114 PolarHBondContact O-OG1 2.95Å; W111-T114 PolarHBondContact O-N 3.49Å; T114-R116 WeakPolarHBondContact CB-O 3.37Å; T114-R116 PolarHBondContact O-N 2.96Å; T114-R116 PolarHBondContact OG1-O 3.46Å
115	Y	84.2	Confident	91	Very high	58 Å²	58	53.1 Å²	53.1	23%	0.227	26%	0.256	C	S	.	.	S	Bend	trans	63.5	-34.1	-174.2	-178.3	-118.6	0	0	0	114.9	D44 R46 W111 I113	D44-Y115 WeakPolarHBondContact CB-OH 3.41Å; D44-Y115 PolarHBondContact O-OH 3.28Å; D44-Y115 VanDerWaalsContact O-OH 3.05Å; D44-Y115 PolarHBondContact OD1-OH 3.14Å; D44-Y115 PolarHBondContact OD2-OH 3.46Å; D44-Y115 VanDerWaalsContact OD2-OH 3.04Å; R46-Y115 HydrophobicContact CB-CD2 4.39Å; R46-Y115 HydrophobicContact CB-CE2 3.83Å; R46-Y115 HydrophobicContact CG-CE2 4.35Å; W111-Y115 WeakPolarHBondContact O-CA 3.3Å; W111-Y115 PolarHBondContact O-N 3.38Å; I113-Y115 VanDerWaalsContact C-N 3.28Å; I113-Y115 PolarHBondContact O-N 3.35Å
116	R	85.5	Confident	91.1	Very high	40 Å²	40	55.1 Å²	55.1	15%	0.151	27%	0.268	C	S	.	.	S	Bend	trans	-125.5	152.3	176.6	-59.1	-60.9	-177.9	97.8	-12.8	110.7	D44 T114 R118 D202	D44-R116 IonicContact OD2-CZ 3.36Å; D44-R116 IonicContact OD2-NH2 3.56Å; D44-R116 PolarHBondContact OD2-NH2 3.11Å; T114-R116 WeakPolarHBondContact CB-O 3.37Å; T114-R116 PolarHBondContact O-N 2.96Å; T114-R116 PolarHBondContact OG1-O 3.46Å; R116-R118 PolarHBondContact O-N 3.12Å; R116-D202 WeakPolarHBondContact CD-OD2 3.39Å
117	F	89.5	Confident	91.2	Very high	26 Å²	26	54 Å²	54	11%	0.114	26%	0.263	C	S	.	.			trans	-65.5	123.5	172.7	-170.3	-104.1	0	0	0	111.8	W111 L123 C124 V127 M191 D202 C203	W111-F117 HydrophobicContact CE3-CB 3.96Å; W111-F117 AromaticContact CE3-CD2 3.6Å; W111-F117 HydrophobicContact CE3-CD2 3.6Å; W111-F117 HydrophobicContact CE3-CG 4.23Å; W111-F117 HydrophobicContact CH2-CB 3.66Å; W111-F117 HydrophobicContact CH2-CD2 4.41Å; W111-F117 HydrophobicContact CH2-CG 4.34Å; W111-F117 HydrophobicContact CZ2-CB 4.26Å; W111-F117 HydrophobicContact CZ3-CB 3.5Å; W111-F117 AromaticContact CZ3-CD2 3.42Å; W111-F117 HydrophobicContact CZ3-CD2 3.42Å; W111-F117 VanDerWaalsContact CZ3-CD2 3.42Å; W111-F117 HydrophobicContact CZ3-CE2 4.4Å; W111-F117 AromaticContact CZ3-CG 3.76Å; W111-F117 HydrophobicContact CZ3-CG 3.76Å; F117-L123 HydrophobicContact CE1-CB 4.43Å; F117-L123 HydrophobicContact CZ-CB 4.28Å; F117-L123 HydrophobicContact CZ-CD2 4.24Å; F117-L123 HydrophobicContact CZ-CG 3.96Å; F117-C124 HydrophobicContact CD1-CB 4.16Å; F117-C124 HydrophobicContact CE1-CB 3.7Å; F117-C124 HydrophobicContact CZ-CB 4.12Å; F117-V127 HydrophobicContact CE2-CB 4.39Å; F117-V127 HydrophobicContact CE2-CG1 4.45Å; F117-V127 HydrophobicContact CE2-CG2 4.24Å; F117-V127 HydrophobicContact CZ-CG2 4.28Å; F117-M191 HydrophobicContact CB-SD 4.4Å; F117-M191 HydrophobicContact CD1-CE 4.29Å; F117-M191 HydrophobicContact CD1-SD 3.58Å; F117-M191 VanDerWaalsContact CD1-SD 3.58Å; F117-M191 HydrophobicContact CE1-SD 4.32Å; F117-M191 HydrophobicContact CG-SD 4.38Å; F117-D202 VanDerWaalsContact CB-OD1 3.28Å; F117-D202 WeakPolarHBondContact CB-OD1 3.4Å; F117-D202 PolarHBondContact N-OD1 3.27Å; F117-C203 HydrophobicContact CB-CB 3.86Å; F117-C203 HydrophobicContact CD1-CB 3.96Å; F117-C203 HydrophobicContact CD2-CB 4.37Å; F117-C203 HydrophobicContact CG-CB 3.8Å
118	R	87.5	Confident	91.4	Very high	195 Å²	195	53 Å²	53	74%	0.736	26%	0.255	S	S	*	.			trans	-99.2	94.5	173.9	-66	-174.3	-178.2	158.9	1.6	109.8	R116	R116-R118 PolarHBondContact O-N 3.12Å
119	G	88.9	Confident	91.6	Very high	26 Å²	26	51.4 Å²	51.4	27%	0.268	25%	0.248	S	C	.	.	S	Bend	trans	173.7	168.3	175.4	0	0	0	0	0	114
120	P	93.1	Very high	91.9	Very high	64 Å²	64	52.1 Å²	52.1	42%	0.416	25%	0.252	S	S	.	.			trans	-72.7	167	172.4	31.3	-35.8	0	0	0	112.1	W122 L123 C124	P120-W122 VanDerWaalsContact C-N 3.35Å; P120-W122 HydrophobicContact CG-CD2 4.3Å; P120-W122 HydrophobicContact CG-CG 4.28Å; P120-W122 HydrophobicContact CG-CZ2 4.11Å; P120-W122 PolarHBondContact O-N 3.28Å; P120-L123 HydrophobicContact CG-CB 3.98Å; P120-L123 PolarHBondContact O-N 2.81Å; P120-L123 VanDerWaalsContact O-N 3.08Å; P120-C124 PolarHBondContact O-N 3.41Å
121	D	93.7	Very high	92	Very high	58 Å²	58	49.8 Å²	49.8	31%	0.31	24%	0.235	S	C	.	.	H	α-helix	trans	-54.7	-43.8	-179.2	-176.9	66.6	0	0	0	113.7	L123 C124 R125 S190 M191	D121-L123 VanDerWaalsContact C-N 3.27Å; D121-L123 PolarHBondContact O-N 3.01Å; D121-C124 WeakPolarHBondContact O-CB 3.5Å; D121-C124 PolarHBondContact O-N 2.9Å; D121-R125 WeakPolarHBondContact O-CG 3.35Å; D121-R125 PolarHBondContact O-N 3.42Å; D121-R125 VanDerWaalsContact O-N 3.11Å; D121-R125 IonicContact OD1-CZ 3.61Å; D121-R125 IonicContact OD1-NE 2.76Å; D121-R125 IonicContact OD1-NH2 3.29Å; D121-R125 PolarHBondContact OD1-NH2 3.26Å; D121-R125 IonicContact OD2-CZ 2.7Å; D121-R125 VanDerWaalsContact OD2-CZ 3.29Å; D121-R125 IonicContact OD2-NE 3.85Å; D121-R125 PolarHBondContact OD2-NE 3.19Å; D121-R125 IonicContact OD2-NH2 3.05Å; D121-R125 PolarHBondContact OD2-NH2 2.96Å; D121-S190 WeakPolarHBondContact OD1-CA 3.45Å; D121-M191 HydrophobicContact CB-CB 4.1Å; D121-M191 HydrophobicContact CB-CG 4.18Å; D121-M191 PolarHBondContact OD1-N 3.47Å
122	W	95	Very high	92.2	Very high	167 Å²	167	48.8 Å²	48.8	63%	0.633	23%	0.232	S	C	*	.	H	α-helix	trans	-61.4	-36.7	179	70.8	-100	0	0	0	112.2	P120 R125 V126	P120-W122 VanDerWaalsContact C-N 3.35Å; P120-W122 HydrophobicContact CG-CD2 4.3Å; P120-W122 HydrophobicContact CG-CG 4.28Å; P120-W122 HydrophobicContact CG-CZ2 4.11Å; P120-W122 PolarHBondContact O-N 3.28Å; W122-R125 PolarHBondContact O-N 2.99Å; W122-V126 HydrophobicContact CE3-CG2 4.35Å; W122-V126 VanDerWaalsContact O-CG2 3.28Å; W122-V126 WeakPolarHBondContact O-CG2 3.38Å; W122-V126 PolarHBondContact O-N 3.05Å
123	L	94.6	Very high	92.7	Very high	55 Å²	55	50 Å²	50	29%	0.288	24%	0.237	S	C	.	.	H	α-helix	trans	-71	-39.3	180	-173.8	64.1	0	0	0	110.5	F117 P120 D121 R125 V126 V127	F117-L123 HydrophobicContact CE1-CB 4.43Å; F117-L123 HydrophobicContact CZ-CB 4.28Å; F117-L123 HydrophobicContact CZ-CD2 4.24Å; F117-L123 HydrophobicContact CZ-CG 3.96Å; P120-L123 HydrophobicContact CG-CB 3.98Å; P120-L123 PolarHBondContact O-N 2.81Å; P120-L123 VanDerWaalsContact O-N 3.08Å; D121-L123 VanDerWaalsContact C-N 3.27Å; D121-L123 PolarHBondContact O-N 3.01Å; L123-R125 PolarHBondContact O-N 3.49Å; L123-V126 PolarHBondContact O-N 3.46Å; L123-V127 HydrophobicContact CD1-CG2 4.26Å; L123-V127 HydrophobicContact CG-CG2 4.29Å; L123-V127 WeakPolarHBondContact O-CB 3.42Å; L123-V127 VanDerWaalsContact O-CG2 3.23Å; L123-V127 WeakPolarHBondContact O-CG2 3.3Å; L123-V127 PolarHBondContact O-N 2.88Å
124	C	94.6	Very high	92.9	Very high	0 Å²	0	45.5 Å²	45.5	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-53.9	-52.2	172.1	157.3	0	0	0	0	111.1	F117 P120 D121 V126 V127 K128 M191 C203	F117-C124 HydrophobicContact CD1-CB 4.16Å; F117-C124 HydrophobicContact CE1-CB 3.7Å; F117-C124 HydrophobicContact CZ-CB 4.12Å; P120-C124 PolarHBondContact O-N 3.41Å; D121-C124 WeakPolarHBondContact O-CB 3.5Å; D121-C124 PolarHBondContact O-N 2.9Å; C124-V126 PolarHBondContact O-N 2.87Å; C124-V127 PolarHBondContact O-N 2.82Å; C124-K128 VanDerWaalsContact O-CG 3.29Å; C124-K128 WeakPolarHBondContact O-CG 3.39Å; C124-K128 PolarHBondContact O-N 2.81Å; C124-M191 HydrophobicContact CB-CG 3.84Å; C124-M191 HydrophobicContact CB-SD 4.09Å; C124-C203 HydrophobicContact CB-CB 3.52Å; C124-C203 WeakPolarHBondContact CB-SG 3.27Å; C124-C203 WeakPolarHBondContact SG-CB 3.49Å; C124-C203 CovalentContact SG-SG 2.01Å; C124-C203 PolarHBondContact SG-SG 3.39Å
125	R	95.5	Very high	93.1	Very high	66 Å²	66	44.4 Å²	44.4	25%	0.249	21%	0.207	C	C	.	.	H	α-helix	trans	-62	-44.9	-179.5	-64.8	-179.4	-163.5	-99.2	-3.7	112.4	D121 W122 L123 K128 H129 Y186 F189 S190	D121-R125 WeakPolarHBondContact O-CG 3.35Å; D121-R125 PolarHBondContact O-N 3.42Å; D121-R125 VanDerWaalsContact O-N 3.11Å; D121-R125 IonicContact OD1-CZ 3.61Å; D121-R125 IonicContact OD1-NE 2.76Å; D121-R125 IonicContact OD1-NH2 3.29Å; D121-R125 PolarHBondContact OD1-NH2 3.26Å; D121-R125 IonicContact OD2-CZ 2.7Å; D121-R125 VanDerWaalsContact OD2-CZ 3.29Å; D121-R125 IonicContact OD2-NE 3.85Å; D121-R125 PolarHBondContact OD2-NE 3.19Å; D121-R125 IonicContact OD2-NH2 3.05Å; D121-R125 PolarHBondContact OD2-NH2 2.96Å; W122-R125 PolarHBondContact O-N 2.99Å; L123-R125 PolarHBondContact O-N 3.49Å; R125-K128 PolarHBondContact O-N 3.41Å; R125-H129 WeakPolarHBondContact O-CB 3.17Å; R125-H129 PolarHBondContact O-N 2.91Å; R125-Y186 HydrophobicContact CB-CD1 3.85Å; R125-Y186 HydrophobicContact CB-CE1 4.27Å; R125-Y186 PolarHBondContact NH1-O 3.38Å; R125-F189 WeakPolarHBondContact CG-O 3.41Å; R125-F189 PolarHBondContact NH1-O 3.03Å; R125-F189 VanDerWaalsContact NH1-O 3.15Å; R125-S190 VanDerWaalsContact NH2-CB 3.3Å
126	V	95.9	Very high	93.7	Very high	46 Å²	46	41.7 Å²	41.7	28%	0.279	20%	0.196	S	C	.	.	H	α-helix	trans	-64.4	-44.6	178.4	170.7	0	0	0	0	111.2	W122 L123 C124 K128 H129 L130 Y186	W122-V126 HydrophobicContact CE3-CG2 4.35Å; W122-V126 VanDerWaalsContact O-CG2 3.28Å; W122-V126 WeakPolarHBondContact O-CG2 3.38Å; W122-V126 PolarHBondContact O-N 3.05Å; L123-V126 PolarHBondContact O-N 3.46Å; C124-V126 PolarHBondContact O-N 2.87Å; V126-K128 PolarHBondContact O-N 3.29Å; V126-H129 PolarHBondContact O-N 3.43Å; V126-L130 HydrophobicContact CG1-CD1 3.78Å; V126-L130 HydrophobicContact CG1-CG 4.26Å; V126-L130 WeakPolarHBondContact O-CB 3.28Å; V126-L130 VanDerWaalsContact O-CG 3.31Å; V126-L130 WeakPolarHBondContact O-CG 3.21Å; V126-L130 PolarHBondContact O-N 3.46Å; V126-Y186 HydrophobicContact CG2-CE1 4.21Å
127	V	95.4	Very high	94.2	Very high	24 Å²	24	39.8 Å²	39.8	15%	0.145	19%	0.188	C	C	.	.	H	α-helix	trans	-59.5	-49.6	176.6	168.4	0	0	0	0	110	P107 F117 L123 C124 H129 L130 Q131	P107-V127 HydrophobicContact CB-CG1 3.72Å; P107-V127 HydrophobicContact CG-CG1 4.33Å; F117-V127 HydrophobicContact CE2-CB 4.39Å; F117-V127 HydrophobicContact CE2-CG1 4.45Å; F117-V127 HydrophobicContact CE2-CG2 4.24Å; F117-V127 HydrophobicContact CZ-CG2 4.28Å; L123-V127 HydrophobicContact CD1-CG2 4.26Å; L123-V127 HydrophobicContact CG-CG2 4.29Å; L123-V127 WeakPolarHBondContact O-CB 3.42Å; L123-V127 VanDerWaalsContact O-CG2 3.23Å; L123-V127 WeakPolarHBondContact O-CG2 3.3Å; L123-V127 PolarHBondContact O-N 2.88Å; C124-V127 PolarHBondContact O-N 2.82Å; V127-H129 VanDerWaalsContact C-N 3.33Å; V127-H129 PolarHBondContact O-N 3.08Å; V127-L130 PolarHBondContact O-N 3.34Å; V127-Q131 HydrophobicContact CG1-CG 4.32Å; V127-Q131 VanDerWaalsContact O-CG 3.27Å; V127-Q131 WeakPolarHBondContact O-CG 3.31Å; V127-Q131 PolarHBondContact O-N 3.33Å
128	K	94.9	Very high	94.5	Very high	9 Å²	9	38.8 Å²	38.8	4%	0.039	19%	0.185	C	C	.	.	H	α-helix	trans	-61.1	-41.1	178.3	-65.6	-69.7	-179.7	-170.5	0	112.2	C124 R125 V126 Q131 V132 Q185 F189 C203	C124-K128 VanDerWaalsContact O-CG 3.29Å; C124-K128 WeakPolarHBondContact O-CG 3.39Å; C124-K128 PolarHBondContact O-N 2.81Å; R125-K128 PolarHBondContact O-N 3.41Å; V126-K128 PolarHBondContact O-N 3.29Å; K128-Q131 PolarHBondContact O-N 3.45Å; K128-V132 WeakPolarHBondContact O-CG2 3.28Å; K128-V132 PolarHBondContact O-N 3.41Å; K128-Q185 HydrophobicContact CB-CB 4.3Å; K128-F189 HydrophobicContact CB-CB 4.15Å; K128-F189 HydrophobicContact CB-CD1 4.48Å; K128-F189 HydrophobicContact CB-CD2 3.99Å; K128-F189 HydrophobicContact CB-CG 3.94Å; K128-F189 HydrophobicContact CD-CD1 3.65Å; K128-F189 HydrophobicContact CD-CD2 4.38Å; K128-F189 HydrophobicContact CD-CE1 3.73Å; K128-F189 HydrophobicContact CD-CE2 4.47Å; K128-F189 HydrophobicContact CD-CG 3.99Å; K128-F189 HydrophobicContact CD-CZ 4.16Å; K128-F189 HydrophobicContact CG-CB 3.85Å; K128-F189 HydrophobicContact CG-CD1 3.69Å; K128-F189 HydrophobicContact CG-CD2 4.09Å; K128-F189 HydrophobicContact CG-CE1 4.26Å; K128-F189 HydrophobicContact CG-CG 3.58Å; K128-C203 VanDerWaalsContact CE-SG 3.52Å
129	H	96.1	Very high	94.9	Very high	3 Å²	3	29.5 Å²	29.5	1%	0.014	15%	0.15	C	C	.	.	H	α-helix	trans	-59	-49.3	173.5	177.4	77.3	0	0	0	112.3	R125 V126 V127 V132 F133 F179 S182 Q185 Y186	R125-H129 WeakPolarHBondContact O-CB 3.17Å; R125-H129 PolarHBondContact O-N 2.91Å; V126-H129 PolarHBondContact O-N 3.43Å; V127-H129 VanDerWaalsContact C-N 3.33Å; V127-H129 PolarHBondContact O-N 3.08Å; H129-V132 PolarHBondContact O-N 3.47Å; H129-F133 VanDerWaalsContact O-CB 3.26Å; H129-F133 WeakPolarHBondContact O-CB 2.98Å; H129-F133 PolarHBondContact O-N 3.4Å; H129-F179 AromaticContact NE2-CD2 3.57Å; H129-F179 AromaticContact NE2-CE2 3.37Å; H129-F179 WeakPolarHBondContact NE2-CE2 3.38Å; H129-S182 PolarHBondContact CE1-OG 3.1Å; H129-S182 PolarHBondContact ND1-O 3.33Å; H129-S182 PolarHBondContact ND1-OG 2.93Å; H129-Q185 HydrophobicContact CB-CB 4.13Å; H129-Y186 HydrophobicContact CB-CD2 4.49Å; H129-Y186 HydrophobicContact CB-CE1 4.41Å; H129-Y186 HydrophobicContact CB-CE2 3.86Å; H129-Y186 AromaticContact CD2-CE2 4Å; H129-Y186 PolarHBondContact CD2-OH 2.91Å; H129-Y186 AromaticContact CE1-CE2 3.8Å; H129-Y186 AromaticContact CG-CE2 3.46Å; H129-Y186 VanDerWaalsContact CG-CE2 3.46Å; H129-Y186 AromaticContact CG-CZ 3.7Å; H129-Y186 AromaticContact ND1-CD2 3.98Å; H129-Y186 AromaticContact ND1-CE2 3.35Å; H129-Y186 WeakPolarHBondContact ND1-CE2 3.48Å
130	L	95.9	Very high	95.3	Very high	43 Å²	43	29.7 Å²	29.7	23%	0.225	14%	0.143	C	C	.	.	H	α-helix	trans	-68.5	-34.9	-178.2	-67.4	173.4	0	0	0	112.7	F103 V126 V127 V132 F133 G134	F103-L130 HydrophobicContact CB-CB 3.73Å; F103-L130 HydrophobicContact CD1-CB 4.16Å; F103-L130 HydrophobicContact CD1-CD1 3.82Å; F103-L130 HydrophobicContact CD2-CB 4.35Å; F103-L130 HydrophobicContact CE1-CD1 3.95Å; F103-L130 HydrophobicContact CG-CB 3.84Å; F103-L130 HydrophobicContact CG-CD1 4.28Å; F103-L130 HydrophobicContact CG-CG 4.5Å; F103-L130 HydrophobicContact CZ-CD1 4.49Å; V126-L130 HydrophobicContact CG1-CD1 3.78Å; V126-L130 HydrophobicContact CG1-CG 4.26Å; V126-L130 WeakPolarHBondContact O-CB 3.28Å; V126-L130 VanDerWaalsContact O-CG 3.31Å; V126-L130 WeakPolarHBondContact O-CG 3.21Å; V126-L130 PolarHBondContact O-N 3.46Å; V127-L130 PolarHBondContact O-N 3.34Å; L130-V132 VanDerWaalsContact C-N 3.33Å; L130-V132 PolarHBondContact O-N 2.91Å; L130-F133 HydrophobicContact CD2-CD1 4.4Å; L130-F133 PolarHBondContact O-N 3.45Å; L130-G134 PolarHBondContact O-N 2.95Å
131	Q	94.6	Very high	95.4	Very high	9 Å²	9	26.8 Å²	26.8	4%	0.042	12%	0.124	C	C	.	.	H	α-helix	trans	-53.9	-52	170.8	-74.8	-166.5	-36.9	0	0	110.5	F103 V127 K128 G134 M135	F103-Q131 WeakPolarHBondContact O-CG 3.19Å; V127-Q131 HydrophobicContact CG1-CG 4.32Å; V127-Q131 VanDerWaalsContact O-CG 3.27Å; V127-Q131 WeakPolarHBondContact O-CG 3.31Å; V127-Q131 PolarHBondContact O-N 3.33Å; K128-Q131 PolarHBondContact O-N 3.45Å; Q131-G134 PolarHBondContact O-N 3.23Å; Q131-M135 PolarHBondContact O-N 2.99Å
132	V	94.6	Very high	95.5	Very high	0 Å²	0	24 Å²	24	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-72.7	-39.4	-177.2	177	0	0	0	0	112.4	M1 K128 H129 L130 G134 M135 F136 Q185 M220	M1-V132 HydrophobicContact CE-CG2 3.12Å; K128-V132 WeakPolarHBondContact O-CG2 3.28Å; K128-V132 PolarHBondContact O-N 3.41Å; H129-V132 PolarHBondContact O-N 3.47Å; L130-V132 VanDerWaalsContact C-N 3.33Å; L130-V132 PolarHBondContact O-N 2.91Å; V132-G134 VanDerWaalsContact C-N 3.3Å; V132-G134 PolarHBondContact O-N 2.67Å; V132-M135 PolarHBondContact O-N 3.32Å; V132-F136 HydrophobicContact CG1-CD2 3.48Å; V132-F136 VanDerWaalsContact CG1-CD2 3.48Å; V132-F136 HydrophobicContact CG1-CE2 3.43Å; V132-F136 VanDerWaalsContact CG1-CE2 3.43Å; V132-F136 WeakPolarHBondContact O-CD2 3.48Å; V132-F136 PolarHBondContact O-N 2.94Å; V132-Q185 HydrophobicContact CB-CG 3.9Å; V132-Q185 HydrophobicContact CG1-CG 4.33Å; V132-Q185 VanDerWaalsContact CG2-CD 3.42Å; V132-Q185 HydrophobicContact CG2-CG 3.77Å; V132-M220 HydrophobicContact CB-CE 4.4Å; V132-M220 HydrophobicContact CG1-CE 3.78Å; V132-M220 HydrophobicContact CG1-SD 3.89Å; V132-M220 HydrophobicContact CG2-CE 3.77Å
133	F	97	Very high	95.6	Very high	30 Å²	30	16.9 Å²	16.9	13%	0.132	8%	0.084	C	C	.	.	H	α-helix	trans	-55.5	-45.2	174.1	169.6	-110.1	0	0	0	111.8	H129 L130 M135 F136 A137 W175 F179	H129-F133 VanDerWaalsContact O-CB 3.26Å; H129-F133 WeakPolarHBondContact O-CB 2.98Å; H129-F133 PolarHBondContact O-N 3.4Å; L130-F133 HydrophobicContact CD2-CD1 4.4Å; L130-F133 PolarHBondContact O-N 3.45Å; F133-M135 PolarHBondContact O-N 3.47Å; F133-F136 PolarHBondContact O-N 3.41Å; F133-A137 VanDerWaalsContact O-CB 3.22Å; F133-A137 WeakPolarHBondContact O-CB 3.32Å; F133-A137 PolarHBondContact O-N 3.37Å; F133-W175 HydrophobicContact CE1-CE3 4.23Å; F133-W175 AromaticContact CE1-CZ3 3.75Å; F133-W175 HydrophobicContact CE1-CZ3 3.75Å; F133-W175 AromaticContact CE2-CE3 3.93Å; F133-W175 HydrophobicContact CE2-CE3 3.93Å; F133-W175 HydrophobicContact CE2-CZ3 4.24Å; F133-W175 AromaticContact CZ-CE3 3.38Å; F133-W175 HydrophobicContact CZ-CE3 3.38Å; F133-W175 AromaticContact CZ-CZ3 3.37Å; F133-W175 HydrophobicContact CZ-CZ3 3.37Å; F133-F179 HydrophobicContact CD2-CB 4.17Å; F133-F179 HydrophobicContact CE2-CB 3.99Å; F133-F179 HydrophobicContact CE2-CD2 4.5Å
134	G	94.6	Very high	95.6	Very high	0 Å²	0	15.2 Å²	15.2	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-58.9	-45.2	176.4	0	0	0	0	0	112.6	V100 L130 Q131 V132 A137 S138	V100-G134 VanDerWaalsContact CG2-C 3.48Å; V100-G134 VanDerWaalsContact CG2-O 3.3Å; V100-G134 WeakPolarHBondContact CG2-O 3.41Å; L130-G134 PolarHBondContact O-N 2.95Å; Q131-G134 PolarHBondContact O-N 3.23Å; V132-G134 VanDerWaalsContact C-N 3.3Å; V132-G134 PolarHBondContact O-N 2.67Å; G134-A137 PolarHBondContact O-N 2.88Å; G134-S138 PolarHBondContact O-N 3.49Å
135	M	93.6	Very high	95.6	Very high	14 Å²	14	15.2 Å²	15.2	7%	0.069	8%	0.076	C	C	.	.	H	α-helix	trans	-61	-48.5	177.6	-65.3	178.2	65.9	0	0	112.2	Q131 V132 F133 A139 I224 W304 F308	Q131-M135 PolarHBondContact O-N 2.99Å; V132-M135 PolarHBondContact O-N 3.32Å; F133-M135 PolarHBondContact O-N 3.47Å; M135-A139 WeakPolarHBondContact O-CB 3.28Å; M135-A139 PolarHBondContact O-N 3.37Å; M135-A139 VanDerWaalsContact O-N 3.15Å; M135-I224 HydrophobicContact CB-CD1 3.86Å; M135-I224 HydrophobicContact CB-CG2 4.21Å; M135-I224 HydrophobicContact CE-CD1 3.78Å; M135-I224 HydrophobicContact CE-CG2 4.01Å; M135-I224 HydrophobicContact SD-CD1 4.25Å; M135-W304 HydrophobicContact CE-CE3 4.32Å; M135-W304 HydrophobicContact CE-CH2 3.32Å; M135-W304 HydrophobicContact CE-CZ2 4.24Å; M135-W304 HydrophobicContact CE-CZ3 3.38Å; M135-W304 HydrophobicContact CG-CH2 4.29Å; M135-W304 HydrophobicContact SD-CH2 4.22Å; M135-F308 HydrophobicContact CE-CZ 4.03Å
136	F	96.6	Very high	95.5	Very high	0 Å²	0	12.1 Å²	12.1	0%	0	6%	0.064	C	C	.	.	H	α-helix	trans	-62.6	-45.8	175.6	-83.4	-74.3	0	0	0	111.4	V132 F133 S138 A139 Y140 S178 L181 M220 G223 I224	V132-F136 HydrophobicContact CG1-CD2 3.48Å; V132-F136 VanDerWaalsContact CG1-CD2 3.48Å; V132-F136 HydrophobicContact CG1-CE2 3.43Å; V132-F136 VanDerWaalsContact CG1-CE2 3.43Å; V132-F136 WeakPolarHBondContact O-CD2 3.48Å; V132-F136 PolarHBondContact O-N 2.94Å; F133-F136 PolarHBondContact O-N 3.41Å; F136-S138 PolarHBondContact O-N 3.31Å; F136-A139 PolarHBondContact O-N 2.95Å; F136-Y140 HydrophobicContact CD1-CD2 4.05Å; F136-Y140 AromaticContact CD1-CE2 3.49Å; F136-Y140 HydrophobicContact CD1-CE2 3.49Å; F136-Y140 VanDerWaalsContact CD1-CE2 3.49Å; F136-Y140 HydrophobicContact CE1-CE2 4.07Å; F136-Y140 WeakPolarHBondContact O-CB 3.45Å; F136-Y140 WeakPolarHBondContact O-CD2 3.15Å; F136-Y140 PolarHBondContact O-N 3.41Å; F136-S178 VanDerWaalsContact C-OG 3.26Å; F136-S178 PolarHBondContact O-OG 3.34Å; F136-L181 HydrophobicContact CD1-CB 3.97Å; F136-L181 HydrophobicContact CD1-CD1 3.79Å; F136-L181 HydrophobicContact CD2-CB 4.21Å; F136-L181 HydrophobicContact CE1-CB 3.74Å; F136-L181 HydrophobicContact CE1-CD1 3.64Å; F136-L181 HydrophobicContact CE1-CG 4.29Å; F136-L181 HydrophobicContact CE2-CB 3.98Å; F136-L181 HydrophobicContact CG-CB 4.23Å; F136-L181 HydrophobicContact CZ-CB 3.75Å; F136-L181 HydrophobicContact CZ-CD1 4.43Å; F136-M220 HydrophobicContact CE2-SD 4.26Å; F136-G223 VanDerWaalsContact CE1-C 3.48Å; F136-I224 HydrophobicContact CD1-CG1 3.86Å; F136-I224 HydrophobicContact CD2-CD1 4.08Å; F136-I224 HydrophobicContact CD2-CG1 3.94Å; F136-I224 HydrophobicContact CE1-CG1 3.59Å; F136-I224 HydrophobicContact CE2-CD1 3.83Å; F136-I224 HydrophobicContact CE2-CG1 3.68Å; F136-I224 HydrophobicContact CG-CG1 4.02Å; F136-I224 HydrophobicContact CZ-CD1 4.1Å; F136-I224 HydrophobicContact CZ-CG1 3.49Å; F136-I224 VanDerWaalsContact CZ-CG1 3.49Å
137	A	97.1	Very high	95.4	Very high	0 Å²	0	10.9 Å²	10.9	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-58.4	-48.6	-178.7	0	0	0	0	0	111.4	A96 F133 G134 M141 W175 S178	A96-A137 HydrophobicContact CB-CB 4.11Å; F133-A137 VanDerWaalsContact O-CB 3.22Å; F133-A137 WeakPolarHBondContact O-CB 3.32Å; F133-A137 PolarHBondContact O-N 3.37Å; G134-A137 PolarHBondContact O-N 2.88Å; A137-M141 VanDerWaalsContact O-CB 3.31Å; A137-M141 WeakPolarHBondContact O-CB 3.41Å; A137-M141 WeakPolarHBondContact O-CG 3.48Å; A137-M141 PolarHBondContact O-N 3.25Å; A137-W175 HydrophobicContact CB-CE3 4.09Å; A137-W175 HydrophobicContact CB-CH2 4.24Å; A137-W175 HydrophobicContact CB-CZ3 3.77Å; A137-S178 VanDerWaalsContact CA-OG 3.28Å; A137-S178 WeakPolarHBondContact CA-OG 3.47Å; A137-S178 PolarHBondContact N-OG 3.45Å
138	S	95	Very high	95.2	Very high	5 Å²	5	9.8 Å²	9.8	4%	0.035	5%	0.052	C	C	.	.	H	α-helix	trans	-62.6	-47.9	178.9	-175.3	0	0	0	0	111.3	D97 G134 F136 Y140 M141 L142	D97-S138 PolarHBondContact OD1-OG 3.12Å; G134-S138 PolarHBondContact O-N 3.49Å; F136-S138 PolarHBondContact O-N 3.31Å; S138-Y140 PolarHBondContact O-N 3.24Å; S138-M141 PolarHBondContact O-N 2.9Å; S138-L142 WeakPolarHBondContact O-CG 3.32Å; S138-L142 PolarHBondContact O-N 3.49Å; S138-L142 VanDerWaalsContact O-N 3.17Å
139	A	95.8	Very high	95	Very high	1 Å²	1	10.3 Å²	10.3	1%	0.008	5%	0.054	C	C	.	.	H	α-helix	trans	-62	-44.3	179.1	0	0	0	0	0	113	M135 F136 L142 V143 P228 Y300	M135-A139 WeakPolarHBondContact O-CB 3.28Å; M135-A139 PolarHBondContact O-N 3.37Å; M135-A139 VanDerWaalsContact O-N 3.15Å; F136-A139 PolarHBondContact O-N 2.95Å; A139-L142 WeakPolarHBondContact O-CB 3.39Å; A139-L142 PolarHBondContact O-N 2.97Å; A139-V143 PolarHBondContact O-N 2.69Å; A139-V143 VanDerWaalsContact O-N 3.12Å; A139-P228 HydrophobicContact CB-CG 4.13Å; A139-Y300 HydrophobicContact CB-CE2 4.17Å
140	Y	97.3	Very high	94.8	Very high	30 Å²	30	13 Å²	13	12%	0.118	6%	0.064	C	C	.	.	H	α-helix	trans	-76.1	-27.9	-177.8	-77.2	-114	0	0	0	111.7	F136 S138 L142 V143 V144 L177 L181 G223 P228	F136-Y140 HydrophobicContact CD1-CD2 4.05Å; F136-Y140 AromaticContact CD1-CE2 3.49Å; F136-Y140 HydrophobicContact CD1-CE2 3.49Å; F136-Y140 VanDerWaalsContact CD1-CE2 3.49Å; F136-Y140 HydrophobicContact CE1-CE2 4.07Å; F136-Y140 WeakPolarHBondContact O-CB 3.45Å; F136-Y140 WeakPolarHBondContact O-CD2 3.15Å; F136-Y140 PolarHBondContact O-N 3.41Å; S138-Y140 PolarHBondContact O-N 3.24Å; Y140-L142 VanDerWaalsContact C-N 3.32Å; Y140-V143 PolarHBondContact O-N 3.38Å; Y140-V144 WeakPolarHBondContact O-CG2 3.43Å; Y140-V144 PolarHBondContact O-N 3.17Å; Y140-L177 HydrophobicContact CD1-CD2 3.69Å; Y140-L177 HydrophobicContact CD1-CG 4.2Å; Y140-L177 HydrophobicContact CE1-CD2 3.37Å; Y140-L177 HydrophobicContact CE1-CG 3.91Å; Y140-L181 HydrophobicContact CE1-CD1 4.12Å; Y140-L181 HydrophobicContact CE2-CD1 4.31Å; Y140-L181 WeakPolarHBondContact OH-CD1 3.37Å; Y140-G223 VanDerWaalsContact CE2-O 3.28Å; Y140-G223 WeakPolarHBondContact CE2-O 3.33Å; Y140-G223 PolarHBondContact OH-O 2.95Å; Y140-G223 VanDerWaalsContact OH-O 3.11Å; Y140-P228 HydrophobicContact CE2-CG 4.2Å
141	M	96.1	Very high	94.5	Very high	3 Å²	3	12.5 Å²	12.5	2%	0.015	6%	0.062	C	C	.	.	H	α-helix	trans	-60	-41.1	167.1	-77.5	-50.9	112.3	0	0	111.5	H92 L93 A96 A137 S138 V144 M145 I171 A174 W175	H92-M141 HydrophobicContact CB-SD 3.89Å; L93-M141 HydrophobicContact CD1-CB 3.95Å; A96-M141 HydrophobicContact CB-CG 4.06Å; A137-M141 VanDerWaalsContact O-CB 3.31Å; A137-M141 WeakPolarHBondContact O-CB 3.41Å; A137-M141 WeakPolarHBondContact O-CG 3.48Å; A137-M141 PolarHBondContact O-N 3.25Å; S138-M141 PolarHBondContact O-N 2.9Å; M141-V144 WeakPolarHBondContact O-CG2 3.5Å; M141-V144 PolarHBondContact O-N 2.89Å; M141-V144 HydrophobicContact SD-CG2 4.3Å; M141-M145 WeakPolarHBondContact O-CB 3.33Å; M141-M145 PolarHBondContact O-N 3.41Å; M141-I171 HydrophobicContact CE-CG2 4.46Å; M141-I171 HydrophobicContact SD-CG2 4.3Å; M141-A174 HydrophobicContact CE-CB 3.32Å; M141-W175 HydrophobicContact CE-CD2 4.4Å; M141-W175 HydrophobicContact CE-CG 4.08Å
142	L	94.8	Very high	94.1	Very high	0 Å²	0	12.5 Å²	12.5	0%	0	6%	0.063	C	C	.	.	H	α-helix	trans	-63.1	-41.9	174	-64.4	177.2	0	0	0	112.4	L93 S138 A139 Y140 M145 T146 I296 Y300	L93-L142 HydrophobicContact CD1-CD2 4.11Å; L93-L142 HydrophobicContact CD1-CG 4.43Å; L93-L142 HydrophobicContact CD2-CD2 3.67Å; S138-L142 WeakPolarHBondContact O-CG 3.32Å; S138-L142 PolarHBondContact O-N 3.49Å; S138-L142 VanDerWaalsContact O-N 3.17Å; A139-L142 WeakPolarHBondContact O-CB 3.39Å; A139-L142 PolarHBondContact O-N 2.97Å; Y140-L142 VanDerWaalsContact C-N 3.32Å; L142-M145 HydrophobicContact CD2-CE 3.73Å; L142-T146 WeakPolarHBondContact O-CB 3.5Å; L142-T146 PolarHBondContact O-N 2.95Å; L142-T146 PolarHBondContact O-OG1 2.65Å; L142-I296 HydrophobicContact CD2-CB 4.49Å; L142-I296 HydrophobicContact CD2-CG2 3.28Å; L142-Y300 HydrophobicContact CD1-CD1 4.31Å; L142-Y300 HydrophobicContact CD1-CD2 3.74Å; L142-Y300 HydrophobicContact CD1-CE2 4.5Å; L142-Y300 HydrophobicContact CD1-CG 3.64Å
143	V	97.1	Very high	93.7	Very high	17 Å²	17	13 Å²	13	10%	0.103	7%	0.066	C	C	.	.	H	α-helix	trans	-60.1	-52.1	176.8	171.6	0	0	0	0	110.5	A139 Y140 M145 T146 A147 P228 I231 L232	A139-V143 PolarHBondContact O-N 2.69Å; A139-V143 VanDerWaalsContact O-N 3.12Å; Y140-V143 PolarHBondContact O-N 3.38Å; V143-M145 PolarHBondContact O-N 3.08Å; V143-T146 PolarHBondContact O-N 3.27Å; V143-A147 WeakPolarHBondContact O-CB 3.38Å; V143-A147 PolarHBondContact O-N 3.24Å; V143-P228 HydrophobicContact CG2-CB 3.87Å; V143-P228 HydrophobicContact CG2-CG 4.35Å; V143-I231 HydrophobicContact CG1-CB 4.36Å; V143-I231 HydrophobicContact CG1-CD1 4.3Å; V143-I231 HydrophobicContact CG1-CG2 3.67Å; V143-L232 HydrophobicContact CG2-CD2 4.49Å; V143-L232 HydrophobicContact CG2-CG 4.36Å
144	V	95.9	Very high	93.2	Very high	19 Å²	19	12.4 Å²	12.4	12%	0.115	7%	0.066	C	C	.	.	H	α-helix	trans	-70	-33.2	-177.4	-62.7	0	0	0	0	113	F89 Y140 M141 A147 D148 M170 A174	F89-V144 HydrophobicContact CD1-CG2 4.39Å; F89-V144 HydrophobicContact CE1-CB 4.35Å; F89-V144 HydrophobicContact CE1-CG2 3.95Å; Y140-V144 WeakPolarHBondContact O-CG2 3.43Å; Y140-V144 PolarHBondContact O-N 3.17Å; M141-V144 WeakPolarHBondContact O-CG2 3.5Å; M141-V144 PolarHBondContact O-N 2.89Å; M141-V144 HydrophobicContact SD-CG2 4.3Å; V144-A147 PolarHBondContact O-N 3.1Å; V144-D148 PolarHBondContact O-N 3.4Å; V144-M170 HydrophobicContact CB-CB 4.15Å; V144-M170 HydrophobicContact CB-CE 4.09Å; V144-M170 HydrophobicContact CG1-CB 4.24Å; V144-M170 VanDerWaalsContact O-CE 3.25Å; V144-M170 WeakPolarHBondContact O-CE 3.5Å; V144-A174 HydrophobicContact CG1-CB 3.79Å; V144-A174 HydrophobicContact CG2-CB 4.22Å
145	M	93.2	Very high	92.7	Very high	1 Å²	1	15.8 Å²	15.8	1%	0.005	8%	0.081	C	C	.	.	H	α-helix	trans	-62.4	-45.4	172.5	-179.5	175.1	63	0	0	110.9	F89 L93 M141 L142 V143 D148 R149 T293 I296	F89-M145 HydrophobicContact CB-CB 4.47Å; F89-M145 HydrophobicContact CB-CG 4.2Å; F89-M145 HydrophobicContact CB-SD 4.42Å; F89-M145 HydrophobicContact CD1-CB 4.09Å; F89-M145 HydrophobicContact CG-CB 4.36Å; F89-M145 HydrophobicContact CG-CG 4.38Å; L93-M145 HydrophobicContact CD2-CE 3.62Å; L93-M145 HydrophobicContact CD2-SD 4.02Å; M141-M145 WeakPolarHBondContact O-CB 3.33Å; M141-M145 PolarHBondContact O-N 3.41Å; L142-M145 HydrophobicContact CD2-CE 3.73Å; V143-M145 PolarHBondContact O-N 3.08Å; M145-D148 PolarHBondContact O-N 2.85Å; M145-R149 WeakPolarHBondContact O-CG 3.23Å; M145-R149 PolarHBondContact O-N 3.22Å; M145-R149 VanDerWaalsContact O-N 3.1Å; M145-T293 HydrophobicContact CE-CG2 3.89Å; M145-T293 HydrophobicContact CG-CG2 3.86Å; M145-T293 HydrophobicContact SD-CG2 3.83Å; M145-I296 HydrophobicContact CE-CD1 3.97Å; M145-I296 HydrophobicContact CE-CG2 4.42Å
146	T	94.4	Very high	92	Very high	0 Å²	0	17.5 Å²	17.5	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-68.3	-40.7	177.4	-58.4	0	0	0	0	111.8	L142 V143 D148 R149 Y150 L232 C235 Y236	L142-T146 WeakPolarHBondContact O-CB 3.5Å; L142-T146 PolarHBondContact O-N 2.95Å; L142-T146 PolarHBondContact O-OG1 2.65Å; V143-T146 PolarHBondContact O-N 3.27Å; T146-D148 VanDerWaalsContact C-N 3.3Å; T146-D148 PolarHBondContact O-N 3.31Å; T146-R149 WeakPolarHBondContact O-CA 3.42Å; T146-R149 WeakPolarHBondContact O-CB 3.48Å; T146-R149 PolarHBondContact O-N 3.36Å; T146-R149 VanDerWaalsContact O-N 3.07Å; T146-Y150 PolarHBondContact O-N 2.74Å; T146-L232 VanDerWaalsContact CB-CD2 3.5Å; T146-L232 HydrophobicContact CG2-CD2 3.84Å; T146-L232 WeakPolarHBondContact OG1-CD2 3.48Å; T146-C235 HydrophobicContact CG2-CB 3.68Å; T146-Y236 HydrophobicContact CG2-CD2 4.04Å; T146-Y236 HydrophobicContact CG2-CE1 4.34Å; T146-Y236 HydrophobicContact CG2-CE2 3.53Å; T146-Y236 PolarHBondContact OG1-OH 3.35Å
147	A	93.7	Very high	90.8	Very high	21 Å²	21	23.1 Å²	23.1	17%	0.174	12%	0.123	C	C	.	.	H	α-helix	trans	-60.3	-39.4	173.9	0	0	0	0	0	111.5	V143 V144 R149 Y150 I151 M170	V143-A147 WeakPolarHBondContact O-CB 3.38Å; V143-A147 PolarHBondContact O-N 3.24Å; V144-A147 PolarHBondContact O-N 3.1Å; A147-R149 VanDerWaalsContact C-N 3.35Å; A147-R149 PolarHBondContact O-N 2.9Å; A147-Y150 WeakPolarHBondContact O-CB 3.46Å; A147-Y150 PolarHBondContact O-N 2.85Å; A147-I151 VanDerWaalsContact O-CG1 3.25Å; A147-I151 WeakPolarHBondContact O-CG1 3.38Å; A147-I151 PolarHBondContact O-N 3.39Å; A147-M170 HydrophobicContact CB-CE 3.63Å
148	D	91.2	Very high	89.4	Confident	0 Å²	0	30.1 Å²	30.1	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-64.5	-38.5	173.4	-179.7	71.6	0	0	0	112.1	R85 F89 V144 M145 T146 I151 A152 R166 M170	R85-D148 IonicContact NH1-OD1 3.21Å; R85-D148 PolarHBondContact NH1-OD1 3.43Å; R85-D148 IonicContact NH1-OD2 3.88Å; F89-D148 HydrophobicContact CE2-CB 3.59Å; F89-D148 VanDerWaalsContact CE2-CG 3.5Å; F89-D148 HydrophobicContact CZ-CB 3.59Å; V144-D148 PolarHBondContact O-N 3.4Å; M145-D148 PolarHBondContact O-N 2.85Å; T146-D148 VanDerWaalsContact C-N 3.3Å; T146-D148 PolarHBondContact O-N 3.31Å; D148-I151 PolarHBondContact O-N 3.17Å; D148-A152 WeakPolarHBondContact O-CB 3.4Å; D148-A152 PolarHBondContact O-N 3.22Å; D148-R166 IonicContact OD1-CZ 3.78Å; D148-R166 IonicContact OD1-NH2 2.77Å; D148-R166 PolarHBondContact OD1-NH2 3.06Å; D148-M170 HydrophobicContact CB-CE 4.37Å
149	R	90.7	Very high	88.1	Confident	21 Å²	21	30.6 Å²	30.6	8%	0.079	16%	0.156	C	C	.	.	H	α-helix	trans	-61.6	-46.3	172.6	-65	-53.5	89.2	175.4	9	111.5	M86 M145 T146 A147 I151 A152 V153 I239 T289 V290 T293	M86-R149 VanDerWaalsContact CE-NH1 3.31Å; M145-R149 WeakPolarHBondContact O-CG 3.23Å; M145-R149 PolarHBondContact O-N 3.22Å; M145-R149 VanDerWaalsContact O-N 3.1Å; T146-R149 WeakPolarHBondContact O-CA 3.42Å; T146-R149 WeakPolarHBondContact O-CB 3.48Å; T146-R149 PolarHBondContact O-N 3.36Å; T146-R149 VanDerWaalsContact O-N 3.07Å; A147-R149 VanDerWaalsContact C-N 3.35Å; A147-R149 PolarHBondContact O-N 2.9Å; R149-I151 PolarHBondContact O-N 3Å; R149-A152 PolarHBondContact O-N 3.33Å; R149-V153 WeakPolarHBondContact O-CG2 3.4Å; R149-V153 PolarHBondContact O-N 3.34Å; R149-I239 HydrophobicContact CB-CD1 4.23Å; R149-T289 PolarHBondContact NH1-OG1 3.44Å; R149-V290 HydrophobicContact CB-CG2 4.43Å; R149-T293 HydrophobicContact CG-CG2 3.88Å
150	Y	91.4	Very high	86.5	Confident	59 Å²	59	36.8 Å²	36.8	23%	0.231	19%	0.188	C	C	.	.	H	α-helix	trans	-55.6	-51.9	175.9	164.9	-103.6	0	0	0	110.9	T146 A147 A152 V153 C154 H155 F238 I239	T146-Y150 PolarHBondContact O-N 2.74Å; A147-Y150 WeakPolarHBondContact O-CB 3.46Å; A147-Y150 PolarHBondContact O-N 2.85Å; Y150-A152 VanDerWaalsContact C-N 3.33Å; Y150-A152 PolarHBondContact O-N 2.84Å; Y150-V153 PolarHBondContact O-N 2.64Å; Y150-C154 HydrophobicContact CD2-CB 4.1Å; Y150-C154 VanDerWaalsContact CD2-SG 3.56Å; Y150-C154 HydrophobicContact CE2-CB 3.84Å; Y150-C154 VanDerWaalsContact O-CB 3.31Å; Y150-C154 WeakPolarHBondContact O-CB 3.15Å; Y150-C154 PolarHBondContact O-N 3.15Å; Y150-H155 AromaticContact CZ-NE2 3.95Å; Y150-H155 PolarHBondContact OH-NE2 2.81Å; Y150-F238 HydrophobicContact CD2-CB 3.85Å; Y150-F238 HydrophobicContact CE2-CB 3.47Å; Y150-F238 VanDerWaalsContact CE2-CB 3.47Å; Y150-F238 HydrophobicContact CE2-CD2 4.1Å; Y150-F238 AromaticContact CE2-CG 3.93Å; Y150-F238 HydrophobicContact CE2-CG 3.93Å; Y150-I239 HydrophobicContact CD2-CG1 4.32Å
151	I	89.7	Confident	85	Confident	33 Å²	33	43.5 Å²	43.5	17%	0.169	22%	0.22	C	C	.	.	H	α-helix	trans	-64.6	-38.7	-179.7	-57.6	160.3	0	0	0	111.1	A147 D148 R149 V153 H155 T159	A147-I151 VanDerWaalsContact O-CG1 3.25Å; A147-I151 WeakPolarHBondContact O-CG1 3.38Å; A147-I151 PolarHBondContact O-N 3.39Å; D148-I151 PolarHBondContact O-N 3.17Å; R149-I151 PolarHBondContact O-N 3Å; I151-V153 VanDerWaalsContact C-N 3.3Å; I151-V153 PolarHBondContact O-N 3Å; I151-H155 HydrophobicContact CG2-CB 4.24Å; I151-H155 CarbonylContact O-C 3.45Å; I151-H155 WeakPolarHBondContact O-CA 3.23Å; I151-H155 PolarHBondContact O-N 3.15Å; I151-H155 VanDerWaalsContact O-O 3.04Å; I151-T159 PolarHBondContact O-OG1 2.92Å
152	A	86.7	Confident	83.7	Confident	8 Å²	8	48.8 Å²	48.8	7%	0.066	25%	0.245	C	C	.	.	H	α-helix	trans	-69.1	-24.9	-179.6	0	0	0	0	0	114.4	D148 R149 Y150 K286	D148-A152 WeakPolarHBondContact O-CB 3.4Å; D148-A152 PolarHBondContact O-N 3.22Å; R149-A152 PolarHBondContact O-N 3.33Å; Y150-A152 VanDerWaalsContact C-N 3.33Å; Y150-A152 PolarHBondContact O-N 2.84Å; A152-K286 PolarHBondContact O-NZ 3.37Å
153	V	86.2	Confident	82.8	Confident	10 Å²	10	50.9 Å²	50.9	6%	0.061	26%	0.259	C	S	.	.	H	α-helix	trans	-93.7	-54.1	178.2	174.9	0	0	0	0	111	R149 Y150 I151 I239 N242 I243 I282 V290	R149-V153 WeakPolarHBondContact O-CG2 3.4Å; R149-V153 PolarHBondContact O-N 3.34Å; Y150-V153 PolarHBondContact O-N 2.64Å; I151-V153 VanDerWaalsContact C-N 3.3Å; I151-V153 PolarHBondContact O-N 3Å; V153-I239 HydrophobicContact CG1-CG2 4.45Å; V153-N242 HydrophobicContact CG1-CB 4.49Å; V153-I243 HydrophobicContact CG1-CG1 4.36Å; V153-I282 HydrophobicContact CG1-CD1 4.04Å; V153-V290 HydrophobicContact CG2-CG2 3.81Å
154	C	86.5	Confident	82.1	Confident	19 Å²	19	52.7 Å²	52.7	13%	0.128	28%	0.276	C	S	.	.	H	α-helix	trans	-80.4	-27.6	-172.6	-61.2	0	0	0	0	113.3	Y150 P156	Y150-C154 HydrophobicContact CD2-CB 4.1Å; Y150-C154 VanDerWaalsContact CD2-SG 3.56Å; Y150-C154 HydrophobicContact CE2-CB 3.84Å; Y150-C154 VanDerWaalsContact O-CB 3.31Å; Y150-C154 WeakPolarHBondContact O-CB 3.15Å; Y150-C154 PolarHBondContact O-N 3.15Å; C154-P156 VanDerWaalsContact C-CD 3.5Å; C154-P156 WeakPolarHBondContact O-CD 3.41Å
155	H	84.4	Confident	81.6	Confident	71 Å²	71	59.8 Å²	59.8	33%	0.329	30%	0.3	S	S	.	.			trans	-129.5	67.2	-178.4	-56.8	-60.3	0	0	0	111.6	Y150 I151 L157 K158 T159	Y150-H155 AromaticContact CZ-NE2 3.95Å; Y150-H155 PolarHBondContact OH-NE2 2.81Å; I151-H155 HydrophobicContact CG2-CB 4.24Å; I151-H155 CarbonylContact O-C 3.45Å; I151-H155 WeakPolarHBondContact O-CA 3.23Å; I151-H155 PolarHBondContact O-N 3.15Å; I151-H155 VanDerWaalsContact O-O 3.04Å; H155-L157 VanDerWaalsContact C-N 3.25Å; H155-L157 PolarHBondContact O-N 2.88Å; H155-K158 HydrophobicContact CB-CB 4.07Å; H155-K158 HydrophobicContact CB-CD 4.27Å; H155-K158 HydrophobicContact CB-CG 4.27Å; H155-K158 PolarHBondContact O-N 3.03Å; H155-T159 PolarHBondContact O-N 2.54Å; H155-T159 PolarHBondContact O-OG1 2.82Å
156	P	77.7	Confident	81.5	Confident	50 Å²	50	62.1 Å²	62.1	33%	0.325	31%	0.309	S	S	.	.	T	Hydrogen-bonded Turn	trans	-59	-36.6	-176.5	23.7	-33.4	0	0	0	112.5	C154 T159	C154-P156 VanDerWaalsContact C-CD 3.5Å; C154-P156 WeakPolarHBondContact O-CD 3.41Å; P156-T159 WeakPolarHBondContact O-CB 3.48Å; P156-T159 PolarHBondContact O-N 3.39Å
157	L	72.6	Confident	81.3	Confident	118 Å²	118	62.1 Å²	62.1	62%	0.618	31%	0.309	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.2	-40.7	-179.5	-61.4	176.7	0	0	0	112.7	H155 T159 L160	H155-L157 VanDerWaalsContact C-N 3.25Å; H155-L157 PolarHBondContact O-N 2.88Å; L157-T159 PolarHBondContact O-N 2.93Å; L157-L160 HydrophobicContact CD2-CD1 4.09Å; L157-L160 WeakPolarHBondContact O-CB 3.45Å; L157-L160 PolarHBondContact O-N 3.34Å; L157-L160 VanDerWaalsContact O-N 3.13Å
158	K	67.5	Low	81.2	Confident	147 Å²	147	68.7 Å²	68.7	64%	0.639	33%	0.329	S	S	*	.	H	α-helix	trans	-63.5	-21.5	174.2	-71.6	-169.5	176.4	-176.8	0	112.8	H155 L160	H155-K158 HydrophobicContact CB-CB 4.07Å; H155-K158 HydrophobicContact CB-CD 4.27Å; H155-K158 HydrophobicContact CB-CG 4.27Å; H155-K158 PolarHBondContact O-N 3.03Å; K158-L160 VanDerWaalsContact C-N 3.34Å
159	T	66.7	Low	81.4	Confident	14 Å²	14	74.5 Å²	74.5	9%	0.086	36%	0.36	C	S	.	.	H	α-helix	trans	-80.7	-15.9	179.3	-62.4	0	0	0	0	112.9	I151 H155 P156 L157	I151-T159 PolarHBondContact O-OG1 2.92Å; H155-T159 PolarHBondContact O-N 2.54Å; H155-T159 PolarHBondContact O-OG1 2.82Å; P156-T159 WeakPolarHBondContact O-CB 3.48Å; P156-T159 PolarHBondContact O-N 3.39Å; L157-T159 PolarHBondContact O-N 2.93Å
160	L	63.4	Low	81.6	Confident	131 Å²	131	75 Å²	75	69%	0.686	36%	0.363	S	S	*	.	H	α-helix	trans	-76.4	-31.2	-178.1	-68.2	168.8	0	0	0	113	L157 K158	L157-L160 HydrophobicContact CD2-CD1 4.09Å; L157-L160 WeakPolarHBondContact O-CB 3.45Å; L157-L160 PolarHBondContact O-N 3.34Å; L157-L160 VanDerWaalsContact O-N 3.13Å; K158-L160 VanDerWaalsContact C-N 3.34Å
161	Q	64.5	Low	81.8	Confident	171 Å²	171	72.4 Å²	72.4	80%	0.799	35%	0.354	S	S	*	.	H	α-helix	trans	-78.9	-42.3	-167.1	-73.6	175.7	-30.4	0	0	113.9
162	Q	69.8	Low	82.2	Confident	115 Å²	115	73.2 Å²	73.2	54%	0.537	37%	0.365	S	S	.	.			trans	-154.3	69.4	177.8	-66.6	-168.8	-10.4	0	0	113.8	A164 R165 R166	Q162-A164 PolarHBondContact O-N 3.21Å; Q162-R165 HydrophobicContact CB-CB 4.49Å; Q162-R166 PolarHBondContact O-N 3Å
163	P	76.1	Confident	82.7	Confident	43 Å²	43	75.4 Å²	75.4	28%	0.279	38%	0.383	S	S	.	.	H	α-helix	trans	-64.7	-40.8	-171.8	22.5	-32.2	0	0	0	114.4	S167	P163-S167 PolarHBondContact O-N 3.03Å; P163-S167 PolarHBondContact O-OG 3.43Å
164	A	81.4	Confident	83.3	Confident	56 Å²	56	75 Å²	75	46%	0.463	38%	0.381	S	S	.	.	H	α-helix	trans	-78.2	-37.4	-173.5	0	0	0	0	0	113.4	Q162 R168	Q162-A164 PolarHBondContact O-N 3.21Å; A164-R168 WeakPolarHBondContact O-CG 3.42Å; A164-R168 PolarHBondContact O-N 3.05Å; A164-R168 VanDerWaalsContact O-N 3.1Å; A164-R168 PolarHBondContact O-NE 2.92Å
165	R	86.5	Confident	83.8	Confident	167 Å²	167	76.7 Å²	76.7	63%	0.63	39%	0.385	S	S	*	.	H	α-helix	trans	-65.1	-44.8	177.2	-172.5	-178.2	-178.8	-178.7	1.9	110.7	Q162 S167 R168 L169	Q162-R165 HydrophobicContact CB-CB 4.49Å; R165-S167 PolarHBondContact O-N 3.44Å; R165-R168 PolarHBondContact O-N 3.39Å; R165-L169 PolarHBondContact O-N 3.31Å
166	R	89.3	Confident	84.5	Confident	51 Å²	51	77.8 Å²	77.8	19%	0.192	40%	0.396	C	S	.	.	H	α-helix	trans	-57.2	-51.2	176.5	-172.3	-173.5	75.9	-158.7	9.3	111.7	D148 Q162 R168 L169 M170	D148-R166 IonicContact OD1-CZ 3.78Å; D148-R166 IonicContact OD1-NH2 2.77Å; D148-R166 PolarHBondContact OD1-NH2 3.06Å; Q162-R166 PolarHBondContact O-N 3Å; R166-R168 VanDerWaalsContact C-N 3.35Å; R166-R168 PolarHBondContact O-N 3.42Å; R166-L169 PolarHBondContact O-N 3.05Å; R166-M170 HydrophobicContact CG-CG 4.42Å; R166-M170 HydrophobicContact CG-SD 3.95Å; R166-M170 VanDerWaalsContact O-CG 3.29Å; R166-M170 WeakPolarHBondContact O-CG 3.38Å; R166-M170 PolarHBondContact O-N 2.91Å
167	S	91	Very high	85.4	Confident	0 Å²	0	79 Å²	79	0%	0	40%	0.399	C	S	.	.	H	α-helix	trans	-62.6	-40.3	-179.8	-65	0	0	0	0	112.9	R85 F89 P163 R165 L169 M170 I171	R85-S167 WeakPolarHBondContact CD-OG 3.35Å; R85-S167 VanDerWaalsContact CG-OG 3.28Å; R85-S167 WeakPolarHBondContact CG-OG 3.48Å; F89-S167 WeakPolarHBondContact CE2-OG 3.38Å; P163-S167 PolarHBondContact O-N 3.03Å; P163-S167 PolarHBondContact O-OG 3.43Å; R165-S167 PolarHBondContact O-N 3.44Å; S167-L169 VanDerWaalsContact C-N 3.34Å; S167-L169 PolarHBondContact O-N 3.39Å; S167-M170 PolarHBondContact O-N 3.3Å; S167-I171 WeakPolarHBondContact O-CB 3.33Å; S167-I171 WeakPolarHBondContact O-CD1 3.45Å; S167-I171 VanDerWaalsContact O-CG1 3.24Å; S167-I171 WeakPolarHBondContact O-CG1 3.36Å; S167-I171 PolarHBondContact O-N 3.1Å
168	R	92.5	Very high	86.6	Confident	158 Å²	158	73.3 Å²	73.3	60%	0.596	37%	0.37	S	S	*	.	H	α-helix	trans	-61.5	-42	174.7	-75.2	-174.6	-70.1	166	-2.6	112.1	L88 A164 R165 R166 I171 A172	L88-R168 HydrophobicContact CD2-CG 3.92Å; A164-R168 WeakPolarHBondContact O-CG 3.42Å; A164-R168 PolarHBondContact O-N 3.05Å; A164-R168 VanDerWaalsContact O-N 3.1Å; A164-R168 PolarHBondContact O-NE 2.92Å; R165-R168 PolarHBondContact O-N 3.39Å; R166-R168 VanDerWaalsContact C-N 3.35Å; R166-R168 PolarHBondContact O-N 3.42Å; R168-I171 PolarHBondContact O-N 3.48Å; R168-A172 WeakPolarHBondContact O-CB 3.25Å; R168-A172 PolarHBondContact O-N 3.11Å
169	L	93.9	Very high	88.1	Confident	122 Å²	122	71.3 Å²	71.3	64%	0.639	36%	0.361	S	S	*	.	H	α-helix	trans	-64.9	-44	176.6	-177.8	63.1	0	0	0	111.8	R165 R166 S167 I171 A172 A173	R165-L169 PolarHBondContact O-N 3.31Å; R166-L169 PolarHBondContact O-N 3.05Å; S167-L169 VanDerWaalsContact C-N 3.34Å; S167-L169 PolarHBondContact O-N 3.39Å; L169-I171 VanDerWaalsContact C-N 3.35Å; L169-I171 PolarHBondContact O-N 2.95Å; L169-A172 PolarHBondContact O-N 3.09Å; L169-A173 VanDerWaalsContact O-CB 3.31Å; L169-A173 WeakPolarHBondContact O-CB 3.45Å; L169-A173 PolarHBondContact O-N 2.93Å
170	M	95.1	Very high	89.5	Confident	32 Å²	32	74.3 Å²	74.3	16%	0.158	38%	0.379	C	S	.	.	H	α-helix	trans	-60.4	-44.5	176.6	-68.1	171	70.1	0	0	111.5	V144 A147 D148 R166 S167 A173 A174	V144-M170 HydrophobicContact CB-CB 4.15Å; V144-M170 HydrophobicContact CB-CE 4.09Å; V144-M170 HydrophobicContact CG1-CB 4.24Å; V144-M170 VanDerWaalsContact O-CE 3.25Å; V144-M170 WeakPolarHBondContact O-CE 3.5Å; A147-M170 HydrophobicContact CB-CE 3.63Å; D148-M170 HydrophobicContact CB-CE 4.37Å; R166-M170 HydrophobicContact CG-CG 4.42Å; R166-M170 HydrophobicContact CG-SD 3.95Å; R166-M170 VanDerWaalsContact O-CG 3.29Å; R166-M170 WeakPolarHBondContact O-CG 3.38Å; R166-M170 PolarHBondContact O-N 2.91Å; S167-M170 PolarHBondContact O-N 3.3Å; M170-A173 PolarHBondContact O-N 3.22Å; M170-A174 PolarHBondContact O-N 3.5Å
171	I	97	Very high	91.1	Very high	5 Å²	5	69.1 Å²	69.1	3%	0.026	35%	0.352	C	S	.	.	H	α-helix	trans	-62.4	-49.8	176.7	-70.2	164.9	0	0	0	110.4	L88 F89 H92 M141 S167 R168 L169 A173 A174 W175	L88-I171 HydrophobicContact CD2-CD1 3.83Å; L88-I171 HydrophobicContact CG-CD1 3.71Å; F89-I171 HydrophobicContact CD1-CD1 3.98Å; F89-I171 HydrophobicContact CD1-CG1 3.98Å; F89-I171 HydrophobicContact CE1-CD1 3.97Å; F89-I171 HydrophobicContact CE1-CG1 3.73Å; H92-I171 HydrophobicContact CB-CG2 4.16Å; M141-I171 HydrophobicContact CE-CG2 4.46Å; M141-I171 HydrophobicContact SD-CG2 4.3Å; S167-I171 WeakPolarHBondContact O-CB 3.33Å; S167-I171 WeakPolarHBondContact O-CD1 3.45Å; S167-I171 VanDerWaalsContact O-CG1 3.24Å; S167-I171 WeakPolarHBondContact O-CG1 3.36Å; S167-I171 PolarHBondContact O-N 3.1Å; R168-I171 PolarHBondContact O-N 3.48Å; L169-I171 VanDerWaalsContact C-N 3.35Å; L169-I171 PolarHBondContact O-N 2.95Å; I171-A173 VanDerWaalsContact C-N 3.33Å; I171-A173 PolarHBondContact O-N 3.43Å; I171-A174 PolarHBondContact O-N 2.94Å; I171-W175 PolarHBondContact O-N 3.39Å
172	A	97.2	Very high	92.6	Very high	49 Å²	49	61 Å²	61	41%	0.405	31%	0.314	S	S	.	.	H	α-helix	trans	-58.6	-44.8	178.7	0	0	0	0	0	111.8	R168 L169 A174 W175 V176	R168-A172 WeakPolarHBondContact O-CB 3.25Å; R168-A172 PolarHBondContact O-N 3.11Å; L169-A172 PolarHBondContact O-N 3.09Å; A172-A174 VanDerWaalsContact C-N 3.32Å; A172-A174 PolarHBondContact O-N 2.89Å; A172-W175 PolarHBondContact O-N 2.93Å; A172-V176 WeakPolarHBondContact O-CG2 3.37Å; A172-V176 PolarHBondContact O-N 3.36Å
173	A	97.5	Very high	93.8	Very high	54 Å²	54	57.9 Å²	57.9	45%	0.446	30%	0.303	S	S	.	.	H	α-helix	trans	-59.5	-42	176.6	0	0	0	0	0	111.9	L169 M170 I171 V176 L177	L169-A173 VanDerWaalsContact O-CB 3.31Å; L169-A173 WeakPolarHBondContact O-CB 3.45Å; L169-A173 PolarHBondContact O-N 2.93Å; M170-A173 PolarHBondContact O-N 3.22Å; I171-A173 VanDerWaalsContact C-N 3.33Å; I171-A173 PolarHBondContact O-N 3.43Å; A173-V176 PolarHBondContact O-N 3.46Å; A173-L177 WeakPolarHBondContact O-CB 3.35Å; A173-L177 PolarHBondContact O-N 2.94Å
174	A	98	Very high	94.7	Very high	3 Å²	3	57.6 Å²	57.6	3%	0.025	30%	0.301	C	S	.	.	H	α-helix	trans	-67.8	-38.2	178.1	0	0	0	0	0	113	M141 V144 M170 I171 A172 S178	M141-A174 HydrophobicContact CE-CB 3.32Å; V144-A174 HydrophobicContact CG1-CB 3.79Å; V144-A174 HydrophobicContact CG2-CB 4.22Å; M170-A174 PolarHBondContact O-N 3.5Å; I171-A174 PolarHBondContact O-N 2.94Å; A172-A174 VanDerWaalsContact C-N 3.32Å; A172-A174 PolarHBondContact O-N 2.89Å; A174-S178 VanDerWaalsContact O-CB 3.3Å; A174-S178 WeakPolarHBondContact O-CB 3.48Å; A174-S178 PolarHBondContact O-N 3.47Å; A174-S178 PolarHBondContact O-OG 2.97Å
175	W	98.4	Very high	95.3	Very high	54 Å²	54	54.9 Å²	54.9	21%	0.205	28%	0.279	C	S	.	.	H	α-helix	trans	-64.6	-47.1	172.9	-78.7	103.4	0	0	0	112.4	H92 L95 A96 F133 A137 M141 I171 A172 S178 F179	H92-W175 AromaticContact ND1-NE1 3.34Å; H92-W175 PolarHBondContact ND1-NE1 2.69Å; L95-W175 HydrophobicContact CB-CZ2 4.38Å; A96-W175 HydrophobicContact CB-CH2 4.2Å; A96-W175 HydrophobicContact CB-CZ2 4.34Å; F133-W175 HydrophobicContact CE1-CE3 4.23Å; F133-W175 AromaticContact CE1-CZ3 3.75Å; F133-W175 HydrophobicContact CE1-CZ3 3.75Å; F133-W175 AromaticContact CE2-CE3 3.93Å; F133-W175 HydrophobicContact CE2-CE3 3.93Å; F133-W175 HydrophobicContact CE2-CZ3 4.24Å; F133-W175 AromaticContact CZ-CE3 3.38Å; F133-W175 HydrophobicContact CZ-CE3 3.38Å; F133-W175 AromaticContact CZ-CZ3 3.37Å; F133-W175 HydrophobicContact CZ-CZ3 3.37Å; A137-W175 HydrophobicContact CB-CE3 4.09Å; A137-W175 HydrophobicContact CB-CH2 4.24Å; A137-W175 HydrophobicContact CB-CZ3 3.77Å; M141-W175 HydrophobicContact CE-CD2 4.4Å; M141-W175 HydrophobicContact CE-CG 4.08Å; I171-W175 PolarHBondContact O-N 3.39Å; A172-W175 PolarHBondContact O-N 2.93Å; W175-S178 PolarHBondContact O-N 2.86Å; W175-F179 PolarHBondContact O-N 3.43Å
176	V	98.2	Very high	95.6	Very high	93 Å²	93	50.9 Å²	50.9	56%	0.564	27%	0.265	S	S	*	.	H	α-helix	trans	-62.1	-46.7	178.3	171.6	0	0	0	0	110.7	A172 A173 S178 F179 V180	A172-V176 WeakPolarHBondContact O-CG2 3.37Å; A172-V176 PolarHBondContact O-N 3.36Å; A173-V176 PolarHBondContact O-N 3.46Å; V176-S178 VanDerWaalsContact C-N 3.3Å; V176-S178 PolarHBondContact O-N 3.09Å; V176-F179 PolarHBondContact O-N 3Å; V176-V180 HydrophobicContact CG1-CG2 4.43Å; V176-V180 WeakPolarHBondContact O-CG2 3.39Å; V176-V180 PolarHBondContact O-N 3.14Å
177	L	97.5	Very high	95.8	Very high	75 Å²	75	56.4 Å²	56.4	39%	0.393	29%	0.29	S	S	.	.	H	α-helix	trans	-62.2	-40.3	178.2	-175.3	56	0	0	0	111.3	Y140 A173 F179 V180 L181	Y140-L177 HydrophobicContact CD1-CD2 3.69Å; Y140-L177 HydrophobicContact CD1-CG 4.2Å; Y140-L177 HydrophobicContact CE1-CD2 3.37Å; Y140-L177 HydrophobicContact CE1-CG 3.91Å; A173-L177 WeakPolarHBondContact O-CB 3.35Å; A173-L177 PolarHBondContact O-N 2.94Å; L177-F179 PolarHBondContact O-N 3.41Å; L177-V180 PolarHBondContact O-N 3.44Å; L177-L181 HydrophobicContact CD1-CD1 3.83Å; L177-L181 HydrophobicContact CD1-CD2 4.35Å; L177-L181 HydrophobicContact CD1-CG 3.87Å; L177-L181 HydrophobicContact CG-CD1 3.76Å; L177-L181 HydrophobicContact CG-CG 4.24Å; L177-L181 WeakPolarHBondContact O-CB 3.09Å; L177-L181 WeakPolarHBondContact O-CG 3.39Å; L177-L181 PolarHBondContact O-N 2.79Å
178	S	98.1	Very high	95.9	Very high	0 Å²	0	57.3 Å²	57.3	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-62.8	-41.4	176.2	-58.5	0	0	0	0	112.4	F136 A137 A174 W175 V176 S182	F136-S178 VanDerWaalsContact C-OG 3.26Å; F136-S178 PolarHBondContact O-OG 3.34Å; A137-S178 VanDerWaalsContact CA-OG 3.28Å; A137-S178 WeakPolarHBondContact CA-OG 3.47Å; A137-S178 PolarHBondContact N-OG 3.45Å; A174-S178 VanDerWaalsContact O-CB 3.3Å; A174-S178 WeakPolarHBondContact O-CB 3.48Å; A174-S178 PolarHBondContact O-N 3.47Å; A174-S178 PolarHBondContact O-OG 2.97Å; W175-S178 PolarHBondContact O-N 2.86Å; V176-S178 VanDerWaalsContact C-N 3.3Å; V176-S178 PolarHBondContact O-N 3.09Å; S178-S182 WeakPolarHBondContact O-CB 3.31Å; S178-S182 PolarHBondContact O-N 2.78Å; S178-S182 PolarHBondContact O-OG 2.99Å; S178-S182 VanDerWaalsContact O-OG 3.08Å
179	F	97.5	Very high	95.9	Very high	105 Å²	105	49.9 Å²	49.9	46%	0.461	27%	0.268	S	S	.	.	H	α-helix	trans	-64.6	-43.6	175.6	-177.9	-95.7	0	0	0	112	H129 F133 W175 V176 L177 S182 T183	H129-F179 AromaticContact NE2-CD2 3.57Å; H129-F179 AromaticContact NE2-CE2 3.37Å; H129-F179 WeakPolarHBondContact NE2-CE2 3.38Å; F133-F179 HydrophobicContact CD2-CB 4.17Å; F133-F179 HydrophobicContact CE2-CB 3.99Å; F133-F179 HydrophobicContact CE2-CD2 4.5Å; W175-F179 PolarHBondContact O-N 3.43Å; V176-F179 PolarHBondContact O-N 3Å; L177-F179 PolarHBondContact O-N 3.41Å; F179-S182 PolarHBondContact O-N 2.91Å; F179-S182 PolarHBondContact O-OG 3.47Å; F179-T183 WeakPolarHBondContact O-CG2 3.35Å; F179-T183 PolarHBondContact O-N 3.29Å
180	V	97.4	Very high	95.9	Very high	76 Å²	76	44.7 Å²	44.7	46%	0.461	24%	0.242	S	C	.	.	H	α-helix	trans	-65.8	-47.2	178.9	172	0	0	0	0	111.1	V176 L177 S182 T183	V176-V180 HydrophobicContact CG1-CG2 4.43Å; V176-V180 WeakPolarHBondContact O-CG2 3.39Å; V176-V180 PolarHBondContact O-N 3.14Å; L177-V180 PolarHBondContact O-N 3.44Å; V180-S182 PolarHBondContact O-N 2.95Å; V180-T183 WeakPolarHBondContact O-CB 3.26Å; V180-T183 WeakPolarHBondContact O-CG2 3.22Å; V180-T183 PolarHBondContact O-N 3.28Å; V180-T183 VanDerWaalsContact O-N 3.1Å; V180-T183 PolarHBondContact O-OG1 3.03Å
181	L	97	Very high	95.8	Very high	22 Å²	22	45 Å²	45	12%	0.115	24%	0.243	C	C	.	.	H	α-helix	trans	-67.4	-21.1	-178.8	-66	173.8	0	0	0	113.3	F136 Y140 L177 P184 W219	F136-L181 HydrophobicContact CD1-CB 3.97Å; F136-L181 HydrophobicContact CD1-CD1 3.79Å; F136-L181 HydrophobicContact CD2-CB 4.21Å; F136-L181 HydrophobicContact CE1-CB 3.74Å; F136-L181 HydrophobicContact CE1-CD1 3.64Å; F136-L181 HydrophobicContact CE1-CG 4.29Å; F136-L181 HydrophobicContact CE2-CB 3.98Å; F136-L181 HydrophobicContact CG-CB 4.23Å; F136-L181 HydrophobicContact CZ-CB 3.75Å; F136-L181 HydrophobicContact CZ-CD1 4.43Å; Y140-L181 HydrophobicContact CE1-CD1 4.12Å; Y140-L181 HydrophobicContact CE2-CD1 4.31Å; Y140-L181 WeakPolarHBondContact OH-CD1 3.37Å; L177-L181 HydrophobicContact CD1-CD1 3.83Å; L177-L181 HydrophobicContact CD1-CD2 4.35Å; L177-L181 HydrophobicContact CD1-CG 3.87Å; L177-L181 HydrophobicContact CG-CD1 3.76Å; L177-L181 HydrophobicContact CG-CG 4.24Å; L177-L181 WeakPolarHBondContact O-CB 3.09Å; L177-L181 WeakPolarHBondContact O-CG 3.39Å; L177-L181 PolarHBondContact O-N 2.79Å; L181-P184 VanDerWaalsContact O-CD 3.28Å; L181-P184 WeakPolarHBondContact O-CD 3.45Å; L181-W219 HydrophobicContact CB-CZ2 4.33Å; L181-W219 HydrophobicContact CD2-CH2 3.44Å; L181-W219 VanDerWaalsContact CD2-CH2 3.44Å; L181-W219 HydrophobicContact CD2-CZ2 3.41Å; L181-W219 VanDerWaalsContact CD2-CZ2 3.41Å; L181-W219 HydrophobicContact CG-CZ2 4.46Å
182	S	96.2	Very high	95.4	Very high	0 Å²	0	46.8 Å²	46.8	0%	0	25%	0.253	C	S	.	.	T	Hydrogen-bonded Turn	trans	-89.1	-3.1	174	67	0	0	0	0	114.2	H129 S178 F179 V180 Q185	H129-S182 PolarHBondContact CE1-OG 3.1Å; H129-S182 PolarHBondContact ND1-O 3.33Å; H129-S182 PolarHBondContact ND1-OG 2.93Å; S178-S182 WeakPolarHBondContact O-CB 3.31Å; S178-S182 PolarHBondContact O-N 2.78Å; S178-S182 PolarHBondContact O-OG 2.99Å; S178-S182 VanDerWaalsContact O-OG 3.08Å; F179-S182 PolarHBondContact O-N 2.91Å; F179-S182 PolarHBondContact O-OG 3.47Å; V180-S182 PolarHBondContact O-N 2.95Å; S182-Q185 WeakPolarHBondContact O-CG 3.19Å; S182-Q185 PolarHBondContact O-N 3.48Å
183	T	95.1	Very high	95	Very high	50 Å²	50	47.8 Å²	47.8	31%	0.307	25%	0.249	S	C	.	.	T	Hydrogen-bonded Turn	trans	-62.7	-30	177.6	58.8	0	0	0	0	115.9	F179 V180 Q185 Y186	F179-T183 WeakPolarHBondContact O-CG2 3.35Å; F179-T183 PolarHBondContact O-N 3.29Å; V180-T183 WeakPolarHBondContact O-CB 3.26Å; V180-T183 WeakPolarHBondContact O-CG2 3.22Å; V180-T183 PolarHBondContact O-N 3.28Å; V180-T183 VanDerWaalsContact O-N 3.1Å; V180-T183 PolarHBondContact O-OG1 3.03Å; T183-Q185 PolarHBondContact O-N 2.83Å; T183-Y186 WeakPolarHBondContact O-CD2 3.5Å; T183-Y186 PolarHBondContact O-N 3.49Å; T183-Y186 VanDerWaalsContact O-N 3.14Å
184	P	94	Very high	94.4	Very high	37 Å²	37	47.2 Å²	47.2	24%	0.24	24%	0.24	C	C	.	.	T	Hydrogen-bonded Turn	trans	-57.3	-21.3	-179.7	-28.2	37.3	0	0	0	114.4	L181 Y186 F187 V188	L181-P184 VanDerWaalsContact O-CD 3.28Å; L181-P184 WeakPolarHBondContact O-CD 3.45Å; P184-Y186 PolarHBondContact O-N 3.21Å; P184-F187 PolarHBondContact O-N 3.03Å; P184-V188 WeakPolarHBondContact O-CG2 3.3Å; P184-V188 PolarHBondContact O-N 3.14Å
185	Q	93.7	Very high	93.5	Very high	0 Å²	0	49.3 Å²	49.3	0%	0	25%	0.25	C	S	.	.	H	α-helix	trans	-57.2	-33	178.5	-56.2	-54.6	-54	0	0	113.1	K128 H129 V132 S182 T183 F187 F189 Y216	K128-Q185 HydrophobicContact CB-CB 4.3Å; H129-Q185 HydrophobicContact CB-CB 4.13Å; V132-Q185 HydrophobicContact CB-CG 3.9Å; V132-Q185 HydrophobicContact CG1-CG 4.33Å; V132-Q185 VanDerWaalsContact CG2-CD 3.42Å; V132-Q185 HydrophobicContact CG2-CG 3.77Å; S182-Q185 WeakPolarHBondContact O-CG 3.19Å; S182-Q185 PolarHBondContact O-N 3.48Å; T183-Q185 PolarHBondContact O-N 2.83Å; Q185-F187 PolarHBondContact O-N 3.2Å; Q185-F189 PolarHBondContact O-N 3.35Å; Q185-F189 VanDerWaalsContact O-N 3.07Å; Q185-Y216 VanDerWaalsContact NE2-CE2 3.33Å; Q185-Y216 PolarHBondContact NE2-OH 2.99Å; Q185-Y216 PolarHBondContact OE1-OH 3.01Å
186	Y	93.6	Very high	92.7	Very high	83 Å²	83	52.1 Å²	52.1	33%	0.325	27%	0.27	S	S	.	.	H	α-helix	trans	-66.5	-25.3	178	-71.6	-72.7	0	0	0	113.3	R125 V126 H129 T183 P184	R125-Y186 HydrophobicContact CB-CD1 3.85Å; R125-Y186 HydrophobicContact CB-CE1 4.27Å; R125-Y186 PolarHBondContact NH1-O 3.38Å; V126-Y186 HydrophobicContact CG2-CE1 4.21Å; H129-Y186 HydrophobicContact CB-CD2 4.49Å; H129-Y186 HydrophobicContact CB-CE1 4.41Å; H129-Y186 HydrophobicContact CB-CE2 3.86Å; H129-Y186 AromaticContact CD2-CE2 4Å; H129-Y186 PolarHBondContact CD2-OH 2.91Å; H129-Y186 AromaticContact CE1-CE2 3.8Å; H129-Y186 AromaticContact CG-CE2 3.46Å; H129-Y186 VanDerWaalsContact CG-CE2 3.46Å; H129-Y186 AromaticContact CG-CZ 3.7Å; H129-Y186 AromaticContact ND1-CD2 3.98Å; H129-Y186 AromaticContact ND1-CE2 3.35Å; H129-Y186 WeakPolarHBondContact ND1-CE2 3.48Å; T183-Y186 WeakPolarHBondContact O-CD2 3.5Å; T183-Y186 PolarHBondContact O-N 3.49Å; T183-Y186 VanDerWaalsContact O-N 3.14Å; P184-Y186 PolarHBondContact O-N 3.21Å
187	F	92.6	Very high	91.9	Very high	166 Å²	166	53.2 Å²	53.2	73%	0.728	28%	0.276	S	S	*	.	H	α-helix	trans	-98.9	-28.7	-179.2	-54.5	-74.2	0	0	0	112.3	P184 Q185	P184-F187 PolarHBondContact O-N 3.03Å; Q185-F187 PolarHBondContact O-N 3.2Å
188	V	92.7	Very high	91.3	Very high	20 Å²	20	53.9 Å²	53.9	12%	0.121	28%	0.283	C	S	.	.	H	α-helix	trans	-83.3	-40.5	-177.6	174.2	0	0	0	0	112	P184 A205 T206 F207 Y216	P184-V188 WeakPolarHBondContact O-CG2 3.3Å; P184-V188 PolarHBondContact O-N 3.14Å; V188-A205 HydrophobicContact CG1-CB 3.85Å; V188-A205 CarbonylContact O-C 3.17Å; V188-A205 VanDerWaalsContact O-CA 3.28Å; V188-A205 WeakPolarHBondContact O-CA 3.44Å; V188-T206 PolarHBondContact O-N 3.39Å; V188-T206 PolarHBondContact O-OG1 2.99Å; V188-F207 HydrophobicContact CG1-CE1 3.64Å; V188-F207 HydrophobicContact CG1-CZ 3.74Å; V188-F207 HydrophobicContact CG2-CE1 4.36Å; V188-Y216 HydrophobicContact CB-CE2 4.44Å; V188-Y216 HydrophobicContact CG1-CD2 4.11Å; V188-Y216 HydrophobicContact CG1-CE2 4.11Å; V188-Y216 HydrophobicContact CG2-CD2 4Å; V188-Y216 HydrophobicContact CG2-CE2 4.25Å
189	F	93.7	Very high	90.5	Very high	1 Å²	1	59.8 Å²	59.8	0%	0.004	31%	0.309	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-99.9	140.9	-174.9	-71.5	-91.9	0	0	0	112.4	M1 R125 K128 Q185 W204 A205 Y216	M1-F189 HydrophobicContact SD-CZ 4.43Å; R125-F189 WeakPolarHBondContact CG-O 3.41Å; R125-F189 PolarHBondContact NH1-O 3.03Å; R125-F189 VanDerWaalsContact NH1-O 3.15Å; K128-F189 HydrophobicContact CB-CB 4.15Å; K128-F189 HydrophobicContact CB-CD1 4.48Å; K128-F189 HydrophobicContact CB-CD2 3.99Å; K128-F189 HydrophobicContact CB-CG 3.94Å; K128-F189 HydrophobicContact CD-CD1 3.65Å; K128-F189 HydrophobicContact CD-CD2 4.38Å; K128-F189 HydrophobicContact CD-CE1 3.73Å; K128-F189 HydrophobicContact CD-CE2 4.47Å; K128-F189 HydrophobicContact CD-CG 3.99Å; K128-F189 HydrophobicContact CD-CZ 4.16Å; K128-F189 HydrophobicContact CG-CB 3.85Å; K128-F189 HydrophobicContact CG-CD1 3.69Å; K128-F189 HydrophobicContact CG-CD2 4.09Å; K128-F189 HydrophobicContact CG-CE1 4.26Å; K128-F189 HydrophobicContact CG-CG 3.58Å; Q185-F189 PolarHBondContact O-N 3.35Å; Q185-F189 VanDerWaalsContact O-N 3.07Å; F189-W204 WeakPolarHBondContact CA-O 3.04Å; F189-A205 HydrophobicContact CD1-CB 4.11Å; F189-A205 HydrophobicContact CE1-CB 3.75Å; F189-A205 HydrophobicContact CE2-CB 4.46Å; F189-A205 HydrophobicContact CZ-CB 3.95Å; F189-Y216 HydrophobicContact CE2-CE2 4.4Å; F189-Y216 AromaticContact CE2-CZ 3.92Å
190	S	93.3	Very high	89.9	Confident	13 Å²	13	56 Å²	56	9%	0.091	30%	0.298	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-154.8	162.4	174.2	60.7	0	0	0	0	111.1	D121 R125 W204	D121-S190 WeakPolarHBondContact OD1-CA 3.45Å; R125-S190 VanDerWaalsContact NH2-CB 3.3Å; S190-W204 PolarHBondContact N-O 2.81Å; S190-W204 PolarHBondContact O-N 3.4Å; S190-W204 VanDerWaalsContact O-O 3.14Å
191	M	92.4	Very high	89.5	Confident	39 Å²	39	59.6 Å²	59.6	19%	0.192	30%	0.303	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-79	118.3	170.8	-76.8	-66.9	-69.5	0	0	110.1	F117 D121 C124 R201 D202 C203	F117-M191 HydrophobicContact CB-SD 4.4Å; F117-M191 HydrophobicContact CD1-CE 4.29Å; F117-M191 HydrophobicContact CD1-SD 3.58Å; F117-M191 VanDerWaalsContact CD1-SD 3.58Å; F117-M191 HydrophobicContact CE1-SD 4.32Å; F117-M191 HydrophobicContact CG-SD 4.38Å; D121-M191 HydrophobicContact CB-CB 4.1Å; D121-M191 HydrophobicContact CB-CG 4.18Å; D121-M191 PolarHBondContact OD1-N 3.47Å; C124-M191 HydrophobicContact CB-CG 3.84Å; C124-M191 HydrophobicContact CB-SD 4.09Å; M191-R201 HydrophobicContact CE-CB 3.78Å; M191-D202 WeakPolarHBondContact CA-O 3.21Å; M191-D202 VanDerWaalsContact SD-C 3.51Å; M191-C203 HydrophobicContact SD-CB 3.61Å; M191-C203 PolarHBondContact SD-N 3.27Å
192	I	89.8	Confident	89.2	Confident	43 Å²	43	59.2 Å²	59.2	22%	0.221	30%	0.301	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.6	159.6	178.6	68.7	169.4	0	0	0	111.3	V194 R201 D202 W204 T206	I192-V194 HydrophobicContact CD1-CG1 4.19Å; I192-V194 HydrophobicContact CG1-CG1 3.92Å; I192-R201 CarbonylContact O-C 3.49Å; I192-R201 WeakPolarHBondContact O-CA 3.44Å; I192-D202 PolarHBondContact N-O 3.47Å; I192-D202 PolarHBondContact O-N 3.17Å; I192-W204 HydrophobicContact CD1-CB 3.45Å; I192-W204 VanDerWaalsContact CD1-CB 3.45Å; I192-W204 HydrophobicContact CD1-CD2 4.09Å; I192-W204 HydrophobicContact CD1-CE3 4.04Å; I192-W204 HydrophobicContact CD1-CG 3.81Å; I192-W204 HydrophobicContact CG1-CB 3.51Å; I192-W204 HydrophobicContact CG1-CG 4.25Å; I192-T206 HydrophobicContact CG2-CG2 3.83Å
193	E	88.7	Confident	89	Confident	70 Å²	70	59.4 Å²	59.4	33%	0.327	30%	0.302	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-80.6	115.1	169	-71.9	177.5	-168.1	0	0	108.8	K199 R201	E193-K199 WeakPolarHBondContact OE2-CD 3.34Å; E193-K199 IonicContact OE2-NZ 3.02Å; E193-K199 PolarHBondContact OE2-NZ 3.49Å; E193-R201 HydrophobicContact CG-CG 3.66Å; E193-R201 IonicContact OE1-CZ 2.92Å; E193-R201 IonicContact OE1-NE 3.71Å; E193-R201 PolarHBondContact OE1-NE 3.39Å; E193-R201 IonicContact OE1-NH2 3.87Å; E193-R201 PolarHBondContact OE1-NH2 3.49Å
194	V	84.2	Confident	88.7	Confident	42 Å²	42	58.7 Å²	58.7	26%	0.255	29%	0.294	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.7	-13.3	-177.1	-61.3	0	0	0	0	113.2	I192 A200 D202	I192-V194 HydrophobicContact CD1-CG1 4.19Å; I192-V194 HydrophobicContact CG1-CG1 3.92Å; V194-A200 WeakPolarHBondContact CG2-O 3.22Å; V194-A200 PolarHBondContact N-O 2.98Å; V194-D202 HydrophobicContact CG1-CB 3.8Å; V194-D202 HydrophobicContact CG2-CB 4.11Å
195	N	80.5	Confident	88.5	Confident	47 Å²	47	57 Å²	57	25%	0.251	28%	0.283	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-134.6	113.7	177.4	-175.8	-40.1	0	0	0	109.6	V197 T198 K199 A200	N195-V197 PolarHBondContact O-N 3Å; N195-V197 WeakPolarHBondContact OD1-CA 3.49Å; N195-V197 WeakPolarHBondContact OD1-CB 3.05Å; N195-V197 PolarHBondContact OD1-N 2.84Å; N195-T198 VanDerWaalsContact CB-OG1 3.28Å; N195-T198 WeakPolarHBondContact CB-OG1 3.25Å; N195-T198 PolarHBondContact ND2-OG1 2.71Å; N195-T198 PolarHBondContact OD1-N 2.88Å; N195-T198 PolarHBondContact OD1-OG1 3.31Å; N195-K199 VanDerWaalsContact O-CA 3.31Å; N195-K199 WeakPolarHBondContact O-CA 3.5Å; N195-K199 PolarHBondContact O-N 3.14Å; N195-A200 HydrophobicContact CB-CB 4.45Å
196	N	79.6	Confident	88.2	Confident	113 Å²	113	60 Å²	60	60%	0.604	30%	0.301	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.5	-26	-178	-74.9	-18.4	0	0	0	113.2
197	V	82.6	Confident	88	Confident	116 Å²	116	59 Å²	59	70%	0.703	30%	0.299	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.4	-51.9	-179.4	-176.3	0	0	0	0	111	N195 K199	N195-V197 PolarHBondContact O-N 3Å; N195-V197 WeakPolarHBondContact OD1-CA 3.49Å; N195-V197 WeakPolarHBondContact OD1-CB 3.05Å; N195-V197 PolarHBondContact OD1-N 2.84Å; V197-K199 VanDerWaalsContact C-N 3.33Å
198	T	84	Confident	87.7	Confident	89 Å²	89	59 Å²	59	55%	0.546	31%	0.305	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86.6	-6.1	-175.6	61	0	0	0	0	113.4	N195 A200	N195-T198 VanDerWaalsContact CB-OG1 3.28Å; N195-T198 WeakPolarHBondContact CB-OG1 3.25Å; N195-T198 PolarHBondContact ND2-OG1 2.71Å; N195-T198 PolarHBondContact OD1-N 2.88Å; N195-T198 PolarHBondContact OD1-OG1 3.31Å; T198-A200 PolarHBondContact O-N 2.92Å; T198-A200 VanDerWaalsContact O-N 3.08Å; T198-A200 WeakPolarHBondContact OG1-CB 3.48Å
199	K	82.9	Confident	87.5	Confident	123 Å²	123	62.6 Å²	62.6	54%	0.535	32%	0.32	S	S	.	.	T	Hydrogen-bonded Turn	trans	52.9	26.1	-172.6	-65.5	-57.5	-162	173.4	0	113.2	E193 N195 V197 R201	E193-K199 WeakPolarHBondContact OE2-CD 3.34Å; E193-K199 IonicContact OE2-NZ 3.02Å; E193-K199 PolarHBondContact OE2-NZ 3.49Å; N195-K199 VanDerWaalsContact O-CA 3.31Å; N195-K199 WeakPolarHBondContact O-CA 3.5Å; N195-K199 PolarHBondContact O-N 3.14Å; V197-K199 VanDerWaalsContact C-N 3.33Å; K199-R201 PolarHBondContact O-N 2.97Å
200	A	85	Confident	87.1	Confident	27 Å²	27	67.8 Å²	67.8	22%	0.223	35%	0.354	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-73	127.7	-177.7	0	0	0	0	0	110.2	V194 N195 T198	V194-A200 WeakPolarHBondContact CG2-O 3.22Å; V194-A200 PolarHBondContact N-O 2.98Å; N195-A200 HydrophobicContact CB-CB 4.45Å; T198-A200 PolarHBondContact O-N 2.92Å; T198-A200 VanDerWaalsContact O-N 3.08Å; T198-A200 WeakPolarHBondContact OG1-CB 3.48Å
201	R	87.9	Confident	86.9	Confident	150 Å²	150	74.5 Å²	74.5	57%	0.566	38%	0.377	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-98.6	146.8	179.9	-65.5	-179.1	178.9	167.8	0.3	111.7	M191 I192 E193 K199	M191-R201 HydrophobicContact CE-CB 3.78Å; I192-R201 CarbonylContact O-C 3.49Å; I192-R201 WeakPolarHBondContact O-CA 3.44Å; E193-R201 HydrophobicContact CG-CG 3.66Å; E193-R201 IonicContact OE1-CZ 2.92Å; E193-R201 IonicContact OE1-NE 3.71Å; E193-R201 PolarHBondContact OE1-NE 3.39Å; E193-R201 IonicContact OE1-NH2 3.87Å; E193-R201 PolarHBondContact OE1-NH2 3.49Å; K199-R201 PolarHBondContact O-N 2.97Å
202	D	90.2	Very high	86.8	Confident	14 Å²	14	73.1 Å²	73.1	8%	0.075	37%	0.373	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-148.2	160.4	175.8	-150.2	1.9	0	0	0	112.4	W111 R116 F117 M191 I192 V194 W204	W111-D202 VanDerWaalsContact CH2-OD1 3.24Å; W111-D202 WeakPolarHBondContact CH2-OD1 3.3Å; W111-D202 VanDerWaalsContact CZ2-CG 3.44Å; W111-D202 WeakPolarHBondContact CZ2-OD1 3.49Å; W111-D202 WeakPolarHBondContact CZ2-OD2 2.95Å; R116-D202 WeakPolarHBondContact CD-OD2 3.39Å; F117-D202 VanDerWaalsContact CB-OD1 3.28Å; F117-D202 WeakPolarHBondContact CB-OD1 3.4Å; F117-D202 PolarHBondContact N-OD1 3.27Å; M191-D202 WeakPolarHBondContact CA-O 3.21Å; M191-D202 VanDerWaalsContact SD-C 3.51Å; I192-D202 PolarHBondContact N-O 3.47Å; I192-D202 PolarHBondContact O-N 3.17Å; V194-D202 HydrophobicContact CG1-CB 3.8Å; V194-D202 HydrophobicContact CG2-CB 4.11Å; D202-W204 PolarHBondContact O-N 3.47Å
203	C	91.9	Very high	86.6	Confident	4 Å²	4	73 Å²	73	3%	0.027	38%	0.376	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-89.7	104.5	-175.9	168.5	0	0	0	0	111.6	W111 F117 C124 K128 M191	W111-C203 HydrophobicContact CH2-CB 3.48Å; W111-C203 VanDerWaalsContact CH2-CB 3.48Å; W111-C203 WeakPolarHBondContact CH2-O 3.37Å; W111-C203 HydrophobicContact CZ3-CB 3.69Å; F117-C203 HydrophobicContact CB-CB 3.86Å; F117-C203 HydrophobicContact CD1-CB 3.96Å; F117-C203 HydrophobicContact CD2-CB 4.37Å; F117-C203 HydrophobicContact CG-CB 3.8Å; C124-C203 HydrophobicContact CB-CB 3.52Å; C124-C203 WeakPolarHBondContact CB-SG 3.27Å; C124-C203 WeakPolarHBondContact SG-CB 3.49Å; C124-C203 CovalentContact SG-SG 2.01Å; C124-C203 PolarHBondContact SG-SG 3.39Å; K128-C203 VanDerWaalsContact CE-SG 3.52Å; M191-C203 HydrophobicContact SD-CB 3.61Å; M191-C203 PolarHBondContact SD-N 3.27Å
204	W	89	Confident	86.8	Confident	35 Å²	35	74.4 Å²	74.4	13%	0.133	38%	0.378	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-131.8	156	-159.4	-137	85	0	0	0	112.1	S4 F189 S190 I192 D202	S4-W204 VanDerWaalsContact C-CZ2 3.48Å; S4-W204 WeakPolarHBondContact O-CH2 3.31Å; S4-W204 WeakPolarHBondContact O-CZ2 3.39Å; S4-W204 VanDerWaalsContact O-CZ3 3.32Å; S4-W204 WeakPolarHBondContact O-CZ3 3.26Å; F189-W204 WeakPolarHBondContact CA-O 3.04Å; S190-W204 PolarHBondContact N-O 2.81Å; S190-W204 PolarHBondContact O-N 3.4Å; S190-W204 VanDerWaalsContact O-O 3.14Å; I192-W204 HydrophobicContact CD1-CB 3.45Å; I192-W204 VanDerWaalsContact CD1-CB 3.45Å; I192-W204 HydrophobicContact CD1-CD2 4.09Å; I192-W204 HydrophobicContact CD1-CE3 4.04Å; I192-W204 HydrophobicContact CD1-CG 3.81Å; I192-W204 HydrophobicContact CG1-CB 3.51Å; I192-W204 HydrophobicContact CG1-CG 4.25Å; D202-W204 PolarHBondContact O-N 3.47Å
205	A	89.6	Confident	87.2	Confident	1 Å²	1	74.6 Å²	74.6	1%	0.008	38%	0.384	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-91.3	114.1	-176.3	0	0	0	0	0	111.5	L3 V188 F189 F207	L3-A205 HydrophobicContact CD2-CB 3.55Å; V188-A205 HydrophobicContact CG1-CB 3.85Å; V188-A205 CarbonylContact O-C 3.17Å; V188-A205 VanDerWaalsContact O-CA 3.28Å; V188-A205 WeakPolarHBondContact O-CA 3.44Å; F189-A205 HydrophobicContact CD1-CB 4.11Å; F189-A205 HydrophobicContact CE1-CB 3.75Å; F189-A205 HydrophobicContact CE2-CB 4.46Å; F189-A205 HydrophobicContact CZ-CB 3.95Å; A205-F207 HydrophobicContact CB-CE2 3.79Å; A205-F207 HydrophobicContact CB-CZ 3.98Å
206	T	88.2	Confident	87.7	Confident	63 Å²	63	73 Å²	73	39%	0.387	38%	0.375	S	S	.	.			trans	-98.5	119.4	-179.4	52.3	0	0	0	0	111	V188 I192	V188-T206 PolarHBondContact O-N 3.39Å; V188-T206 PolarHBondContact O-OG1 2.99Å; I192-T206 HydrophobicContact CG2-CG2 3.83Å
207	F	88.4	Confident	88.3	Confident	63 Å²	63	67.8 Å²	67.8	28%	0.276	35%	0.347	S	S	.	.			trans	-113.2	120.8	176.2	-59.1	-72	0	0	0	110.1	L3 V188 A205 Q209 G212 Y216	L3-F207 HydrophobicContact CD2-CE2 4.08Å; L3-F207 HydrophobicContact CD2-CZ 4.19Å; V188-F207 HydrophobicContact CG1-CE1 3.64Å; V188-F207 HydrophobicContact CG1-CZ 3.74Å; V188-F207 HydrophobicContact CG2-CE1 4.36Å; A205-F207 HydrophobicContact CB-CE2 3.79Å; A205-F207 HydrophobicContact CB-CZ 3.98Å; F207-Q209 VanDerWaalsContact C-N 3.27Å; F207-Q209 PolarHBondContact O-N 2.86Å; F207-G212 VanDerWaalsContact CD1-C 3.4Å; F207-G212 WeakPolarHBondContact CE1-O 3.28Å; F207-Y216 HydrophobicContact CE1-CD2 4.45Å; F207-Y216 AromaticContact CE1-CG 4Å; F207-Y216 HydrophobicContact CE1-CG 4Å; F207-Y216 HydrophobicContact CZ-CD1 4.1Å; F207-Y216 AromaticContact CZ-CG 3.91Å; F207-Y216 HydrophobicContact CZ-CG 3.91Å
208	I	86.4	Confident	88.8	Confident	167 Å²	167	64.5 Å²	64.5	86%	0.856	33%	0.327	S	S	*	.	S	Bend	trans	-67.4	-33.4	177.9	-59.6	170	0	0	0	110.9
209	Q	89	Confident	89.4	Confident	94 Å²	94	65.7 Å²	65.7	44%	0.439	32%	0.322	S	S	.	.	S	Bend	trans	-112	145.5	-173.4	-65.1	-66.9	-27.8	0	0	110.7	F207 W211 G212	F207-Q209 VanDerWaalsContact C-N 3.27Å; F207-Q209 PolarHBondContact O-N 2.86Å; Q209-W211 HydrophobicContact CB-CD2 3.93Å; Q209-W211 VanDerWaalsContact CB-CE2 3.46Å; Q209-W211 HydrophobicContact CB-CG 4.21Å; Q209-W211 HydrophobicContact CB-CZ2 3.82Å; Q209-W211 HydrophobicContact CG-CZ2 3.71Å; Q209-W211 PolarHBondContact O-N 3.41Å; Q209-G212 WeakPolarHBondContact O-CA 3.46Å; Q209-G212 PolarHBondContact O-N 3.09Å
210	P	85.5	Confident	89.9	Confident	110 Å²	110	60.3 Å²	60.3	71%	0.714	30%	0.299	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.4	-26.5	-178.1	25.7	-34.8	0	0	0	112.9	G212	P210-G212 VanDerWaalsContact C-N 3.26Å; P210-G212 PolarHBondContact O-N 2.87Å
211	W	88.6	Confident	90.4	Very high	155 Å²	155	59.3 Å²	59.3	59%	0.587	29%	0.29	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80	-4.6	173.8	54.7	-100.8	0	0	0	113.4	Q209 S213 R214 A215	Q209-W211 HydrophobicContact CB-CD2 3.93Å; Q209-W211 VanDerWaalsContact CB-CE2 3.46Å; Q209-W211 HydrophobicContact CB-CG 4.21Å; Q209-W211 HydrophobicContact CB-CZ2 3.82Å; Q209-W211 HydrophobicContact CG-CZ2 3.71Å; Q209-W211 PolarHBondContact O-N 3.41Å; W211-S213 PolarHBondContact O-N 2.94Å; W211-R214 WeakPolarHBondContact O-CB 3.46Å; W211-R214 PolarHBondContact O-N 3.43Å; W211-A215 HydrophobicContact CE3-CB 3.83Å; W211-A215 HydrophobicContact CZ3-CB 4.05Å; W211-A215 WeakPolarHBondContact O-CB 3.43Å; W211-A215 PolarHBondContact O-N 3Å
212	G	90.1	Very high	90.8	Very high	9 Å²	9	53.5 Å²	53.5	9%	0.093	28%	0.276	C	S	.	.	H	α-helix	trans	-62.2	-42.7	-174.3	0	0	0	0	0	113.4	F207 Q209 P210 A215 Y216	F207-G212 VanDerWaalsContact CD1-C 3.4Å; F207-G212 WeakPolarHBondContact CE1-O 3.28Å; Q209-G212 WeakPolarHBondContact O-CA 3.46Å; Q209-G212 PolarHBondContact O-N 3.09Å; P210-G212 VanDerWaalsContact C-N 3.26Å; P210-G212 PolarHBondContact O-N 2.87Å; G212-A215 PolarHBondContact O-N 3.35Å; G212-Y216 VanDerWaalsContact O-CB 3.25Å; G212-Y216 WeakPolarHBondContact O-CB 3.19Å; G212-Y216 PolarHBondContact O-N 2.95Å
213	S	87.2	Confident	91.1	Very high	41 Å²	41	53.3 Å²	53.3	29%	0.287	28%	0.278	S	S	.	.	H	α-helix	trans	-63.5	-42.5	175.4	58.2	0	0	0	0	111.7	W211 Y216 V217	W211-S213 PolarHBondContact O-N 2.94Å; S213-Y216 PolarHBondContact O-N 2.95Å; S213-V217 WeakPolarHBondContact O-CG2 3.45Å; S213-V217 PolarHBondContact O-N 3.47Å
214	R	91.2	Very high	91.2	Very high	100 Å²	100	53.2 Å²	53.2	38%	0.377	28%	0.277	S	S	.	.	H	α-helix	trans	-59.5	-49.8	174.4	-63.3	-177	174.4	160.1	5.4	112.3	W211 Y216 T218 V315 W316	W211-R214 WeakPolarHBondContact O-CB 3.46Å; W211-R214 PolarHBondContact O-N 3.43Å; R214-Y216 PolarHBondContact O-N 2.9Å; R214-T218 WeakPolarHBondContact O-CB 3.06Å; R214-T218 PolarHBondContact O-N 3.5Å; R214-T218 PolarHBondContact O-OG1 3.44Å; R214-V315 HydrophobicContact CB-CG1 3.9Å; R214-V315 HydrophobicContact CG-CG1 3.5Å; R214-V315 PolarHBondContact NE-O 3.42Å; R214-W316 HydrophobicContact CB-CZ2 4.42Å
215	A	92.7	Very high	91.6	Very high	46 Å²	46	52.8 Å²	52.8	38%	0.38	28%	0.276	S	S	.	.	H	α-helix	trans	-62.3	-43.6	177.4	0	0	0	0	0	111.5	W211 G212 T218 W219	W211-A215 HydrophobicContact CE3-CB 3.83Å; W211-A215 HydrophobicContact CZ3-CB 4.05Å; W211-A215 WeakPolarHBondContact O-CB 3.43Å; W211-A215 PolarHBondContact O-N 3Å; G212-A215 PolarHBondContact O-N 3.35Å; A215-T218 PolarHBondContact O-N 3.4Å; A215-W219 VanDerWaalsContact O-CB 3.23Å; A215-W219 WeakPolarHBondContact O-CB 3.33Å; A215-W219 PolarHBondContact O-N 3.3Å
216	Y	92.4	Very high	91.9	Very high	13 Å²	13	56 Å²	56	5%	0.051	30%	0.295	C	S	.	.	H	α-helix	trans	-63.9	-50.9	-179.5	178.3	-99.1	0	0	0	112.7	M1 L3 Q185 V188 F189 F207 G212 S213 R214 T218 W219 M220	M1-Y216 HydrophobicContact SD-CE1 3.88Å; M1-Y216 PolarHBondContact SD-OH 3.45Å; L3-Y216 HydrophobicContact CD1-CD1 3.92Å; L3-Y216 HydrophobicContact CD1-CE1 4.13Å; L3-Y216 HydrophobicContact CD2-CD1 4.39Å; L3-Y216 HydrophobicContact CD2-CE1 4.36Å; Q185-Y216 VanDerWaalsContact NE2-CE2 3.33Å; Q185-Y216 PolarHBondContact NE2-OH 2.99Å; Q185-Y216 PolarHBondContact OE1-OH 3.01Å; V188-Y216 HydrophobicContact CB-CE2 4.44Å; V188-Y216 HydrophobicContact CG1-CD2 4.11Å; V188-Y216 HydrophobicContact CG1-CE2 4.11Å; V188-Y216 HydrophobicContact CG2-CD2 4Å; V188-Y216 HydrophobicContact CG2-CE2 4.25Å; F189-Y216 HydrophobicContact CE2-CE2 4.4Å; F189-Y216 AromaticContact CE2-CZ 3.92Å; F207-Y216 HydrophobicContact CE1-CD2 4.45Å; F207-Y216 AromaticContact CE1-CG 4Å; F207-Y216 HydrophobicContact CE1-CG 4Å; F207-Y216 HydrophobicContact CZ-CD1 4.1Å; F207-Y216 AromaticContact CZ-CG 3.91Å; F207-Y216 HydrophobicContact CZ-CG 3.91Å; G212-Y216 VanDerWaalsContact O-CB 3.25Å; G212-Y216 WeakPolarHBondContact O-CB 3.19Å; G212-Y216 PolarHBondContact O-N 2.95Å; S213-Y216 PolarHBondContact O-N 2.95Å; R214-Y216 PolarHBondContact O-N 2.9Å; Y216-T218 VanDerWaalsContact C-N 3.3Å; Y216-T218 PolarHBondContact O-N 2.93Å; Y216-W219 WeakPolarHBondContact O-CB 3.29Å; Y216-W219 PolarHBondContact O-N 2.88Å; Y216-M220 HydrophobicContact CD1-CG 4.41Å; Y216-M220 HydrophobicContact CE1-CG 3.98Å; Y216-M220 HydrophobicContact CE2-CG 4.1Å; Y216-M220 HydrophobicContact CE2-SD 4.46Å; Y216-M220 WeakPolarHBondContact O-CB 3.39Å; Y216-M220 VanDerWaalsContact O-CG 3.22Å; Y216-M220 WeakPolarHBondContact O-CG 3.4Å; Y216-M220 PolarHBondContact O-N 3.47Å
217	V	91.6	Very high	92.4	Very high	4 Å²	4	54.8 Å²	54.8	2%	0.024	29%	0.292	C	S	.	.	H	α-helix	trans	-66.1	-37	178.6	174.2	0	0	0	0	111	L3 S213 M220 T221 Q311 M312 V315	L3-V217 HydrophobicContact CD1-CG2 3.34Å; S213-V217 WeakPolarHBondContact O-CG2 3.45Å; S213-V217 PolarHBondContact O-N 3.47Å; V217-M220 PolarHBondContact O-N 2.87Å; V217-T221 WeakPolarHBondContact O-CB 3.4Å; V217-T221 PolarHBondContact O-N 3.27Å; V217-T221 PolarHBondContact O-OG1 3.42Å; V217-Q311 HydrophobicContact CG1-CB 4.06Å; V217-M312 HydrophobicContact CG1-SD 4.13Å; V217-V315 HydrophobicContact CB-CG1 4.34Å; V217-V315 HydrophobicContact CB-CG2 4.1Å; V217-V315 HydrophobicContact CG1-CB 4.5Å; V217-V315 HydrophobicContact CG1-CG2 4.11Å; V217-V315 HydrophobicContact CG2-CG2 3.92Å
218	T	94.1	Very high	92.8	Very high	46 Å²	46	51.8 Å²	51.8	28%	0.282	28%	0.279	S	S	.	.	H	α-helix	trans	-65.6	-43	176	-58.5	0	0	0	0	112.1	R214 A215 Y216 G222 M312 W316	R214-T218 WeakPolarHBondContact O-CB 3.06Å; R214-T218 PolarHBondContact O-N 3.5Å; R214-T218 PolarHBondContact O-OG1 3.44Å; A215-T218 PolarHBondContact O-N 3.4Å; Y216-T218 VanDerWaalsContact C-N 3.3Å; Y216-T218 PolarHBondContact O-N 2.93Å; T218-G222 WeakPolarHBondContact O-CA 3.35Å; T218-G222 PolarHBondContact O-N 3Å; T218-M312 HydrophobicContact CG2-CE 4.1Å; T218-W316 WeakPolarHBondContact OG1-CZ2 3.47Å; T218-W316 PolarHBondContact OG1-NE1 3.45Å; T218-W316 VanDerWaalsContact OG1-NE1 3.1Å
219	W	95.1	Very high	93.3	Very high	114 Å²	114	45.7 Å²	45.7	43%	0.432	25%	0.249	S	C	.	.	H	α-helix	trans	-58.9	-48.7	173.9	167.3	-99.4	0	0	0	111.6	L181 A215 Y216 G222 G223	L181-W219 HydrophobicContact CB-CZ2 4.33Å; L181-W219 HydrophobicContact CD2-CH2 3.44Å; L181-W219 VanDerWaalsContact CD2-CH2 3.44Å; L181-W219 HydrophobicContact CD2-CZ2 3.41Å; L181-W219 VanDerWaalsContact CD2-CZ2 3.41Å; L181-W219 HydrophobicContact CG-CZ2 4.46Å; A215-W219 VanDerWaalsContact O-CB 3.23Å; A215-W219 WeakPolarHBondContact O-CB 3.33Å; A215-W219 PolarHBondContact O-N 3.3Å; Y216-W219 WeakPolarHBondContact O-CB 3.29Å; Y216-W219 PolarHBondContact O-N 2.88Å; W219-G222 PolarHBondContact O-N 3.33Å; W219-G223 PolarHBondContact O-N 3.35Å
220	M	93.9	Very high	93.7	Very high	11 Å²	11	45.4 Å²	45.4	5%	0.054	25%	0.254	C	S	.	.	H	α-helix	trans	-62.9	-47.6	-179.5	-72.4	-66.6	-68.5	0	0	111.6	M1 V132 F136 Y216 V217 I224	M1-M220 HydrophobicContact CE-CE 3.58Å; M1-M220 HydrophobicContact SD-CE 4.21Å; V132-M220 HydrophobicContact CB-CE 4.4Å; V132-M220 HydrophobicContact CG1-CE 3.78Å; V132-M220 HydrophobicContact CG1-SD 3.89Å; V132-M220 HydrophobicContact CG2-CE 3.77Å; F136-M220 HydrophobicContact CE2-SD 4.26Å; Y216-M220 HydrophobicContact CD1-CG 4.41Å; Y216-M220 HydrophobicContact CE1-CG 3.98Å; Y216-M220 HydrophobicContact CE2-CG 4.1Å; Y216-M220 HydrophobicContact CE2-SD 4.46Å; Y216-M220 WeakPolarHBondContact O-CB 3.39Å; Y216-M220 VanDerWaalsContact O-CG 3.22Å; Y216-M220 WeakPolarHBondContact O-CG 3.4Å; Y216-M220 PolarHBondContact O-N 3.47Å; V217-M220 PolarHBondContact O-N 2.87Å; M220-I224 HydrophobicContact CE-CD1 3.34Å; M220-I224 VanDerWaalsContact O-CB 3.27Å; M220-I224 WeakPolarHBondContact O-CB 3.18Å; M220-I224 WeakPolarHBondContact O-CG1 3.35Å; M220-I224 PolarHBondContact O-N 3.23Å; M220-I224 HydrophobicContact SD-CD1 4.11Å
221	T	95.1	Very high	94.2	Very high	6 Å²	6	43.5 Å²	43.5	4%	0.037	24%	0.237	C	C	.	.	H	α-helix	trans	-64.1	-43	176.4	-57.3	0	0	0	0	111.7	V217 F225 V226 F308 M312	V217-T221 WeakPolarHBondContact O-CB 3.4Å; V217-T221 PolarHBondContact O-N 3.27Å; V217-T221 PolarHBondContact O-OG1 3.42Å; T221-F225 WeakPolarHBondContact O-CA 3.42Å; T221-F225 WeakPolarHBondContact O-CB 3.35Å; T221-F225 PolarHBondContact O-N 3.45Å; T221-V226 HydrophobicContact CG2-CG2 4.03Å; T221-V226 PolarHBondContact O-N 2.86Å; T221-F308 HydrophobicContact CG2-CB 3.94Å; T221-F308 HydrophobicContact CG2-CD1 3.9Å; T221-F308 HydrophobicContact CG2-CG 4.17Å; T221-F308 WeakPolarHBondContact OG1-CD1 3.22Å; T221-M312 HydrophobicContact CG2-CE 3.6Å; T221-M312 HydrophobicContact CG2-CG 3.76Å; T221-M312 HydrophobicContact CG2-SD 4.12Å
222	G	96.8	Very high	94.6	Very high	27 Å²	27	36.1 Å²	36.1	28%	0.278	21%	0.209	S	C	.	.	I	π-helix	trans	-59.3	-49.9	177.4	0	0	0	0	0	112.2	T218 W219 A227	T218-G222 WeakPolarHBondContact O-CA 3.35Å; T218-G222 PolarHBondContact O-N 3Å; W219-G222 PolarHBondContact O-N 3.33Å; G222-A227 VanDerWaalsContact O-CB 3.27Å; G222-A227 WeakPolarHBondContact O-CB 3.46Å; G222-A227 PolarHBondContact O-N 3.21Å
223	G	96.1	Very high	94.8	Very high	11 Å²	11	38 Å²	38	11%	0.113	23%	0.228	C	C	.	.	I	π-helix	trans	-76.7	-42	-175.4	0	0	0	0	0	114.3	F136 Y140 W219 P228	F136-G223 VanDerWaalsContact CE1-C 3.48Å; Y140-G223 VanDerWaalsContact CE2-O 3.28Å; Y140-G223 WeakPolarHBondContact CE2-O 3.33Å; Y140-G223 PolarHBondContact OH-O 2.95Å; Y140-G223 VanDerWaalsContact OH-O 3.11Å; W219-G223 PolarHBondContact O-N 3.35Å; G223-P228 WeakPolarHBondContact O-CD 3.43Å
224	I	95.1	Very high	95.2	Very high	1 Å²	1	39.4 Å²	39.4	1%	0.005	24%	0.235	C	C	.	.	I	π-helix	trans	-88.9	-28.1	-173.2	-61.2	175.3	0	0	0	112	M135 F136 M220 P228 Y300 F308	M135-I224 HydrophobicContact CB-CD1 3.86Å; M135-I224 HydrophobicContact CB-CG2 4.21Å; M135-I224 HydrophobicContact CE-CD1 3.78Å; M135-I224 HydrophobicContact CE-CG2 4.01Å; M135-I224 HydrophobicContact SD-CD1 4.25Å; F136-I224 HydrophobicContact CD1-CG1 3.86Å; F136-I224 HydrophobicContact CD2-CD1 4.08Å; F136-I224 HydrophobicContact CD2-CG1 3.94Å; F136-I224 HydrophobicContact CE1-CG1 3.59Å; F136-I224 HydrophobicContact CE2-CD1 3.83Å; F136-I224 HydrophobicContact CE2-CG1 3.68Å; F136-I224 HydrophobicContact CG-CG1 4.02Å; F136-I224 HydrophobicContact CZ-CD1 4.1Å; F136-I224 HydrophobicContact CZ-CG1 3.49Å; F136-I224 VanDerWaalsContact CZ-CG1 3.49Å; M220-I224 HydrophobicContact CE-CD1 3.34Å; M220-I224 VanDerWaalsContact O-CB 3.27Å; M220-I224 WeakPolarHBondContact O-CB 3.18Å; M220-I224 WeakPolarHBondContact O-CG1 3.35Å; M220-I224 PolarHBondContact O-N 3.23Å; M220-I224 HydrophobicContact SD-CD1 4.11Å; I224-P228 WeakPolarHBondContact O-CG 3.18Å; I224-Y300 PolarHBondContact O-OH 3.36Å; I224-F308 HydrophobicContact CB-CE1 4.42Å; I224-F308 HydrophobicContact CB-CZ 3.8Å; I224-F308 HydrophobicContact CG2-CE2 4.04Å; I224-F308 HydrophobicContact CG2-CZ 3.57Å
225	F	95.9	Very high	95.4	Very high	26 Å²	26	35.3 Å²	35.3	11%	0.114	22%	0.221	C	C	.	.	I	π-helix	trans	-120.7	-61.8	-174	-176.2	-109.6	0	0	0	113.4	T221 A227 P228 V229 Y300 W304 A305 F308	T221-F225 WeakPolarHBondContact O-CA 3.42Å; T221-F225 WeakPolarHBondContact O-CB 3.35Å; T221-F225 PolarHBondContact O-N 3.45Å; F225-A227 PolarHBondContact O-N 2.68Å; F225-P228 WeakPolarHBondContact O-CD 3.26Å; F225-V229 HydrophobicContact CD2-CG2 3.88Å; F225-V229 HydrophobicContact CE1-CG2 4.42Å; F225-V229 HydrophobicContact CE2-CG2 3.66Å; F225-V229 HydrophobicContact CG-CG2 4.35Å; F225-V229 HydrophobicContact CZ-CG2 3.93Å; F225-V229 WeakPolarHBondContact O-CB 3.22Å; F225-V229 VanDerWaalsContact O-CG2 3.23Å; F225-V229 WeakPolarHBondContact O-CG2 3.4Å; F225-V229 PolarHBondContact O-N 3.01Å; F225-Y300 WeakPolarHBondContact CA-OH 3.4Å; F225-Y300 HydrophobicContact CD2-CE1 4.45Å; F225-W304 HydrophobicContact CD2-CB 4.02Å; F225-W304 HydrophobicContact CE2-CB 4.23Å; F225-A305 HydrophobicContact CE1-CB 4.44Å; F225-A305 HydrophobicContact CE2-CB 4Å; F225-A305 HydrophobicContact CZ-CB 3.55Å; F225-F308 HydrophobicContact CB-CB 4.38Å; F225-F308 HydrophobicContact CB-CD1 4.34Å; F225-F308 HydrophobicContact CB-CD2 3.39Å; F225-F308 HydrophobicContact CB-CE2 3.63Å; F225-F308 HydrophobicContact CB-CG 3.78Å; F225-F308 HydrophobicContact CB-CZ 4.2Å; F225-F308 HydrophobicContact CD1-CB 4.07Å; F225-F308 HydrophobicContact CD1-CD2 4.31Å; F225-F308 HydrophobicContact CD1-CG 4.38Å; F225-F308 AromaticContact CD2-CD2 3.83Å; F225-F308 HydrophobicContact CD2-CD2 3.83Å; F225-F308 HydrophobicContact CD2-CE2 4.35Å; F225-F308 HydrophobicContact CG-CB 4.21Å; F225-F308 AromaticContact CG-CD2 3.59Å; F225-F308 HydrophobicContact CG-CD2 3.59Å; F225-F308 HydrophobicContact CG-CE2 4.22Å; F225-F308 HydrophobicContact CG-CG 4.05Å
226	V	97.1	Very high	95.5	Very high	68 Å²	68	33.8 Å²	33.8	41%	0.412	21%	0.206	S	C	.	.	I	π-helix	trans	-62.3	-51.1	-170.5	178.1	0	0	0	0	111.7	T221 V229 V230	T221-V226 HydrophobicContact CG2-CG2 4.03Å; T221-V226 PolarHBondContact O-N 2.86Å; V226-V229 PolarHBondContact O-N 2.93Å; V226-V230 HydrophobicContact CG1-CG2 4.3Å; V226-V230 WeakPolarHBondContact O-CB 3.36Å; V226-V230 VanDerWaalsContact O-CG2 3.3Å; V226-V230 WeakPolarHBondContact O-CG2 3.28Å; V226-V230 PolarHBondContact O-N 3.44Å
227	A	97.1	Very high	95.6	Very high	38 Å²	38	35.1 Å²	35.1	31%	0.314	22%	0.224	S	C	.	.	H	α-helix	trans	-60.7	-49.7	179.4	0	0	0	0	0	112.1	G222 F225 V229 V230 I231	G222-A227 VanDerWaalsContact O-CB 3.27Å; G222-A227 WeakPolarHBondContact O-CB 3.46Å; G222-A227 PolarHBondContact O-N 3.21Å; F225-A227 PolarHBondContact O-N 2.68Å; A227-V229 PolarHBondContact O-N 3.45Å; A227-V230 PolarHBondContact O-N 2.96Å; A227-I231 WeakPolarHBondContact O-CD1 3.44Å; A227-I231 VanDerWaalsContact O-CG1 3.22Å; A227-I231 WeakPolarHBondContact O-CG1 3.48Å; A227-I231 PolarHBondContact O-N 3.32Å
228	P	97	Very high	95.7	Very high	1 Å²	1	40.5 Å²	40.5	1%	0.006	25%	0.247	C	C	.	.	H	α-helix	trans	-54.3	-49.3	171.1	-31.6	38.9	0	0	0	113.7	A139 Y140 V143 G223 I224 F225 V230 I231 L232 Y300	A139-P228 HydrophobicContact CB-CG 4.13Å; Y140-P228 HydrophobicContact CE2-CG 4.2Å; V143-P228 HydrophobicContact CG2-CB 3.87Å; V143-P228 HydrophobicContact CG2-CG 4.35Å; G223-P228 WeakPolarHBondContact O-CD 3.43Å; I224-P228 WeakPolarHBondContact O-CG 3.18Å; F225-P228 WeakPolarHBondContact O-CD 3.26Å; P228-V230 PolarHBondContact O-N 3.1Å; P228-I231 PolarHBondContact O-N 3.35Å; P228-L232 HydrophobicContact CB-CD1 4.46Å; P228-L232 VanDerWaalsContact O-CB 3.24Å; P228-L232 WeakPolarHBondContact O-CB 3.22Å; P228-L232 WeakPolarHBondContact O-CD1 3.39Å; P228-L232 WeakPolarHBondContact O-CG 3.47Å; P228-L232 PolarHBondContact O-N 3.18Å; P228-Y300 HydrophobicContact CB-CE1 4.43Å
229	V	96.9	Very high	95.6	Very high	38 Å²	38	38.3 Å²	38.3	23%	0.23	23%	0.234	C	C	.	.	H	α-helix	trans	-61.6	-42.7	-178.2	171.8	0	0	0	0	112.2	F225 V226 A227 L232 G233 Y300 I301	F225-V229 HydrophobicContact CD2-CG2 3.88Å; F225-V229 HydrophobicContact CE1-CG2 4.42Å; F225-V229 HydrophobicContact CE2-CG2 3.66Å; F225-V229 HydrophobicContact CG-CG2 4.35Å; F225-V229 HydrophobicContact CZ-CG2 3.93Å; F225-V229 WeakPolarHBondContact O-CB 3.22Å; F225-V229 VanDerWaalsContact O-CG2 3.23Å; F225-V229 WeakPolarHBondContact O-CG2 3.4Å; F225-V229 PolarHBondContact O-N 3.01Å; V226-V229 PolarHBondContact O-N 2.93Å; A227-V229 PolarHBondContact O-N 3.45Å; V229-L232 PolarHBondContact O-N 3.32Å; V229-G233 PolarHBondContact O-N 2.89Å; V229-Y300 HydrophobicContact CG2-CE1 4.05Å; V229-I301 HydrophobicContact CG1-CD1 4.41Å; V229-I301 HydrophobicContact CG2-CD1 4.48Å; V229-I301 HydrophobicContact CG2-CG1 3.97Å
230	V	97.2	Very high	95.4	Very high	88 Å²	88	36.3 Å²	36.3	53%	0.533	24%	0.236	S	C	.	.	H	α-helix	trans	-63.5	-45.6	176.5	171.5	0	0	0	0	111	V226 A227 P228 T234	V226-V230 HydrophobicContact CG1-CG2 4.3Å; V226-V230 WeakPolarHBondContact O-CB 3.36Å; V226-V230 VanDerWaalsContact O-CG2 3.3Å; V226-V230 WeakPolarHBondContact O-CG2 3.28Å; V226-V230 PolarHBondContact O-N 3.44Å; A227-V230 PolarHBondContact O-N 2.96Å; P228-V230 PolarHBondContact O-N 3.1Å; V230-T234 WeakPolarHBondContact O-CB 3.35Å; V230-T234 VanDerWaalsContact O-CG2 3.27Å; V230-T234 WeakPolarHBondContact O-CG2 3.37Å; V230-T234 PolarHBondContact O-N 3.41Å; V230-T234 PolarHBondContact O-OG1 3.09Å
231	I	97.2	Very high	95.3	Very high	70 Å²	70	42.9 Å²	42.9	36%	0.359	26%	0.261	S	S	.	.	H	α-helix	trans	-66.3	-41.7	179.1	-62.6	164.5	0	0	0	111	V143 A227 P228 T234 C235	V143-I231 HydrophobicContact CG1-CB 4.36Å; V143-I231 HydrophobicContact CG1-CD1 4.3Å; V143-I231 HydrophobicContact CG1-CG2 3.67Å; A227-I231 WeakPolarHBondContact O-CD1 3.44Å; A227-I231 VanDerWaalsContact O-CG1 3.22Å; A227-I231 WeakPolarHBondContact O-CG1 3.48Å; A227-I231 PolarHBondContact O-N 3.32Å; P228-I231 PolarHBondContact O-N 3.35Å; I231-T234 WeakPolarHBondContact CA-OG1 3.3Å; I231-T234 PolarHBondContact O-OG1 3.3Å; I231-C235 VanDerWaalsContact O-CB 3.31Å; I231-C235 WeakPolarHBondContact O-CB 3.31Å; I231-C235 PolarHBondContact O-N 3.48Å; I231-C235 PolarHBondContact O-SG 2.97Å
232	L	96.4	Very high	95	Very high	1 Å²	1	44.5 Å²	44.5	1%	0.005	27%	0.27	C	S	.	.	H	α-helix	trans	-65.7	-46.9	178.6	-69.6	171	0	0	0	111	V143 T146 P228 V229 C235 Y236 V297 Y300	V143-L232 HydrophobicContact CG2-CD2 4.49Å; V143-L232 HydrophobicContact CG2-CG 4.36Å; T146-L232 VanDerWaalsContact CB-CD2 3.5Å; T146-L232 HydrophobicContact CG2-CD2 3.84Å; T146-L232 WeakPolarHBondContact OG1-CD2 3.48Å; P228-L232 HydrophobicContact CB-CD1 4.46Å; P228-L232 VanDerWaalsContact O-CB 3.24Å; P228-L232 WeakPolarHBondContact O-CB 3.22Å; P228-L232 WeakPolarHBondContact O-CD1 3.39Å; P228-L232 WeakPolarHBondContact O-CG 3.47Å; P228-L232 PolarHBondContact O-N 3.18Å; V229-L232 PolarHBondContact O-N 3.32Å; L232-C235 PolarHBondContact O-N 3.28Å; L232-Y236 VanDerWaalsContact O-CD2 3.23Å; L232-Y236 WeakPolarHBondContact O-CD2 3.45Å; L232-Y236 PolarHBondContact O-N 3.21Å; L232-V297 HydrophobicContact CB-CG1 4.01Å; L232-V297 HydrophobicContact CD1-CG1 3.86Å; L232-V297 HydrophobicContact CD1-CG2 4.04Å; L232-V297 HydrophobicContact CD2-CG1 4.47Å; L232-V297 HydrophobicContact CD2-CG2 3.8Å; L232-V297 HydrophobicContact CG-CG1 4.33Å; L232-V297 HydrophobicContact CG-CG2 4.43Å; L232-Y300 HydrophobicContact CD1-CD1 4.34Å; L232-Y300 HydrophobicContact CD1-CE1 4.36Å
233	G	95.4	Very high	94.6	Very high	47 Å²	47	45.2 Å²	45.2	49%	0.485	27%	0.267	S	S	.	.	H	α-helix	trans	-59.7	-46.2	177.6	0	0	0	0	0	112.4	V229 G237	V229-G233 PolarHBondContact O-N 2.89Å; G233-G237 PolarHBondContact O-N 3.06Å
234	T	95.6	Very high	94.2	Very high	71 Å²	71	51.3 Å²	51.3	44%	0.436	29%	0.287	S	S	.	.	H	α-helix	trans	-64	-46.1	176.1	52.5	0	0	0	0	111.9	V230 I231 Y236 G237 F238	V230-T234 WeakPolarHBondContact O-CB 3.35Å; V230-T234 VanDerWaalsContact O-CG2 3.27Å; V230-T234 WeakPolarHBondContact O-CG2 3.37Å; V230-T234 PolarHBondContact O-N 3.41Å; V230-T234 PolarHBondContact O-OG1 3.09Å; I231-T234 WeakPolarHBondContact CA-OG1 3.3Å; I231-T234 PolarHBondContact O-OG1 3.3Å; T234-Y236 PolarHBondContact O-N 3.44Å; T234-G237 PolarHBondContact O-N 2.97Å; T234-F238 WeakPolarHBondContact O-CD2 3.46Å; T234-F238 PolarHBondContact O-N 3.17Å
235	C	95.6	Very high	93.8	Very high	14 Å²	14	53.4 Å²	53.4	10%	0.095	30%	0.301	C	S	.	.	H	α-helix	trans	-58.2	-48.7	176.7	-75	0	0	0	0	112.3	T146 I231 L232 F238 I239	T146-C235 HydrophobicContact CG2-CB 3.68Å; I231-C235 VanDerWaalsContact O-CB 3.31Å; I231-C235 WeakPolarHBondContact O-CB 3.31Å; I231-C235 PolarHBondContact O-N 3.48Å; I231-C235 PolarHBondContact O-SG 2.97Å; L232-C235 PolarHBondContact O-N 3.28Å; C235-F238 PolarHBondContact O-N 2.7Å; C235-I239 WeakPolarHBondContact O-CD1 3.25Å; C235-I239 WeakPolarHBondContact O-CG1 3.25Å; C235-I239 PolarHBondContact O-N 3.39Å
236	Y	94.3	Very high	93.2	Very high	14 Å²	14	53.5 Å²	53.5	6%	0.055	30%	0.302	C	S	.	.	H	α-helix	trans	-67.9	-35.4	177.7	-78.6	-63.5	0	0	0	112.8	T146 L232 T234 F238 I239 C240 V290 T293 F294 V297	T146-Y236 HydrophobicContact CG2-CD2 4.04Å; T146-Y236 HydrophobicContact CG2-CE1 4.34Å; T146-Y236 HydrophobicContact CG2-CE2 3.53Å; T146-Y236 PolarHBondContact OG1-OH 3.35Å; L232-Y236 VanDerWaalsContact O-CD2 3.23Å; L232-Y236 WeakPolarHBondContact O-CD2 3.45Å; L232-Y236 PolarHBondContact O-N 3.21Å; T234-Y236 PolarHBondContact O-N 3.44Å; Y236-F238 VanDerWaalsContact C-N 3.33Å; Y236-F238 PolarHBondContact O-N 3.47Å; Y236-I239 HydrophobicContact CD1-CD1 4.01Å; Y236-I239 HydrophobicContact CE1-CD1 4.23Å; Y236-I239 PolarHBondContact O-N 2.92Å; Y236-C240 VanDerWaalsContact O-CB 3.3Å; Y236-C240 WeakPolarHBondContact O-CB 3.28Å; Y236-C240 PolarHBondContact O-N 3Å; Y236-C240 PolarHBondContact O-SG 3.26Å; Y236-V290 HydrophobicContact CE1-CG1 4.39Å; Y236-T293 WeakPolarHBondContact OH-CB 3.1Å; Y236-T293 PolarHBondContact OH-O 3.37Å; Y236-T293 PolarHBondContact OH-OG1 2.97Å; Y236-F294 HydrophobicContact CD1-CB 4.49Å; Y236-F294 AromaticContact CD1-CD2 3.97Å; Y236-F294 HydrophobicContact CD1-CD2 3.97Å; Y236-F294 HydrophobicContact CD2-CD2 4.37Å; Y236-F294 HydrophobicContact CE1-CB 3.89Å; Y236-F294 HydrophobicContact CE1-CD2 4.15Å; Y236-F294 HydrophobicContact CG-CD2 4.11Å; Y236-F294 WeakPolarHBondContact OH-CA 3.42Å; Y236-F294 PolarHBondContact OH-N 2.66Å; Y236-F294 VanDerWaalsContact OH-N 3.08Å; Y236-V297 HydrophobicContact CD2-CG1 4.3Å; Y236-V297 HydrophobicContact CE2-CB 3.85Å; Y236-V297 HydrophobicContact CE2-CG1 3.84Å; Y236-V297 HydrophobicContact CE2-CG2 3.83Å
237	G	93.5	Very high	92.5	Very high	42 Å²	42	54.2 Å²	54.2	43%	0.433	31%	0.307	S	S	.	.	H	α-helix	trans	-54	-50.2	171.8	0	0	0	0	0	111.5	G233 T234 C240 Y241	G233-G237 PolarHBondContact O-N 3.06Å; T234-G237 PolarHBondContact O-N 2.97Å; G237-C240 PolarHBondContact O-N 3.45Å; G237-Y241 WeakPolarHBondContact O-CB 3.4Å; G237-Y241 PolarHBondContact O-N 2.89Å
238	F	94.3	Very high	91.9	Very high	116 Å²	116	60.1 Å²	60.1	51%	0.509	32%	0.321	S	S	.	.	H	α-helix	trans	-67.3	-38.8	176.3	-71	-65.5	0	0	0	113.7	Y150 T234 C235 Y236 Y241 N242	Y150-F238 HydrophobicContact CD2-CB 3.85Å; Y150-F238 HydrophobicContact CE2-CB 3.47Å; Y150-F238 VanDerWaalsContact CE2-CB 3.47Å; Y150-F238 HydrophobicContact CE2-CD2 4.1Å; Y150-F238 AromaticContact CE2-CG 3.93Å; Y150-F238 HydrophobicContact CE2-CG 3.93Å; T234-F238 WeakPolarHBondContact O-CD2 3.46Å; T234-F238 PolarHBondContact O-N 3.17Å; C235-F238 PolarHBondContact O-N 2.7Å; Y236-F238 VanDerWaalsContact C-N 3.33Å; Y236-F238 PolarHBondContact O-N 3.47Å; F238-Y241 PolarHBondContact O-N 2.98Å; F238-N242 VanDerWaalsContact O-CB 3.31Å; F238-N242 WeakPolarHBondContact O-CB 3.31Å; F238-N242 PolarHBondContact O-N 2.95Å
239	I	92.2	Very high	91.1	Very high	0 Å²	0	62 Å²	62	0%	0	34%	0.341	C	S	.	.	H	α-helix	trans	-61	-48.8	176.6	-70.6	164.4	0	0	0	110.1	R149 Y150 V153 C235 Y236 N242 I243 V290	R149-I239 HydrophobicContact CB-CD1 4.23Å; Y150-I239 HydrophobicContact CD2-CG1 4.32Å; V153-I239 HydrophobicContact CG1-CG2 4.45Å; C235-I239 WeakPolarHBondContact O-CD1 3.25Å; C235-I239 WeakPolarHBondContact O-CG1 3.25Å; C235-I239 PolarHBondContact O-N 3.39Å; Y236-I239 HydrophobicContact CD1-CD1 4.01Å; Y236-I239 HydrophobicContact CE1-CD1 4.23Å; Y236-I239 PolarHBondContact O-N 2.92Å; I239-N242 PolarHBondContact O-N 2.98Å; I239-I243 HydrophobicContact CG2-CD1 3.67Å; I239-I243 HydrophobicContact CG2-CG1 4.44Å; I239-I243 WeakPolarHBondContact O-CB 3.49Å; I239-I243 VanDerWaalsContact O-CG1 3.24Å; I239-I243 WeakPolarHBondContact O-CG1 3.34Å; I239-I243 PolarHBondContact O-N 3.45Å; I239-V290 HydrophobicContact CG2-CG1 3.65Å; I239-V290 HydrophobicContact CG2-CG2 4.39Å
240	C	91.4	Very high	90	Very high	72 Å²	72	65 Å²	65	49%	0.486	35%	0.351	S	S	.	.	H	α-helix	trans	-61.9	-45	178.5	-71.9	0	0	0	0	111.3	Y236 G237 N242 I243 W244	Y236-C240 VanDerWaalsContact O-CB 3.3Å; Y236-C240 WeakPolarHBondContact O-CB 3.28Å; Y236-C240 PolarHBondContact O-N 3Å; Y236-C240 PolarHBondContact O-SG 3.26Å; G237-C240 PolarHBondContact O-N 3.45Å; C240-N242 PolarHBondContact O-N 3.49Å; C240-I243 PolarHBondContact O-N 2.93Å; C240-W244 WeakPolarHBondContact O-CB 3.28Å; C240-W244 PolarHBondContact O-N 3.05Å
241	Y	91.3	Very high	88.9	Confident	149 Å²	149	64.8 Å²	64.8	58%	0.584	35%	0.35	S	S	*	.	H	α-helix	trans	-58.6	-48	174.9	178.4	-99	0	0	0	111.9	G237 F238 I243 W244 C245	G237-Y241 WeakPolarHBondContact O-CB 3.4Å; G237-Y241 PolarHBondContact O-N 2.89Å; F238-Y241 PolarHBondContact O-N 2.98Å; Y241-I243 PolarHBondContact O-N 2.87Å; Y241-W244 PolarHBondContact O-N 2.94Å; Y241-C245 PolarHBondContact O-N 3.3Å; Y241-C245 PolarHBondContact O-SG 2.98Å; Y241-C245 VanDerWaalsContact O-SG 3.34Å
242	N	89	Confident	87.9	Confident	40 Å²	40	64.2 Å²	64.2	21%	0.214	36%	0.356	C	S	.	.	H	α-helix	trans	-63.6	-41.2	179.6	-168.6	-72.5	0	0	0	112.1	V153 F238 I239 C240 N246	V153-N242 HydrophobicContact CG1-CB 4.49Å; F238-N242 VanDerWaalsContact O-CB 3.31Å; F238-N242 WeakPolarHBondContact O-CB 3.31Å; F238-N242 PolarHBondContact O-N 2.95Å; I239-N242 PolarHBondContact O-N 2.98Å; C240-N242 PolarHBondContact O-N 3.49Å; N242-N246 WeakPolarHBondContact O-CB 3.49Å; N242-N246 PolarHBondContact O-N 2.94Å; N242-N246 PolarHBondContact O-ND2 2.95Å; N242-N246 PolarHBondContact OD1-ND2 3.31Å
243	I	87.5	Confident	86.5	Confident	42 Å²	42	67 Å²	67	22%	0.215	38%	0.375	C	S	.	.	H	α-helix	trans	-62.1	-46.6	174.5	-69.2	167.5	0	0	0	110.1	V153 I239 C240 Y241 N246 V247 I282	V153-I243 HydrophobicContact CG1-CG1 4.36Å; I239-I243 HydrophobicContact CG2-CD1 3.67Å; I239-I243 HydrophobicContact CG2-CG1 4.44Å; I239-I243 WeakPolarHBondContact O-CB 3.49Å; I239-I243 VanDerWaalsContact O-CG1 3.24Å; I239-I243 WeakPolarHBondContact O-CG1 3.34Å; I239-I243 PolarHBondContact O-N 3.45Å; C240-I243 PolarHBondContact O-N 2.93Å; Y241-I243 PolarHBondContact O-N 2.87Å; I243-N246 PolarHBondContact O-N 3.09Å; I243-V247 HydrophobicContact CG2-CG2 4.41Å; I243-V247 WeakPolarHBondContact O-CG2 3.35Å; I243-V247 PolarHBondContact O-N 3.5Å; I243-I282 HydrophobicContact CB-CD1 4.48Å; I243-I282 HydrophobicContact CG1-CD1 3.75Å
244	W	88.1	Confident	85	Confident	140 Å²	140	74.6 Å²	74.6	53%	0.53	39%	0.389	S	S	.	.	H	α-helix	trans	-61.9	-47.1	179.6	179.4	80.8	0	0	0	112.3	C240 Y241 N246 V247 R248	C240-W244 WeakPolarHBondContact O-CB 3.28Å; C240-W244 PolarHBondContact O-N 3.05Å; Y241-W244 PolarHBondContact O-N 2.94Å; W244-N246 VanDerWaalsContact C-N 3.31Å; W244-N246 PolarHBondContact O-N 3.19Å; W244-V247 PolarHBondContact O-N 3.47Å; W244-R248 WeakPolarHBondContact O-CB 3.35Å; W244-R248 PolarHBondContact O-N 3.39Å
245	C	87.1	Confident	83.3	Confident	45 Å²	45	78.3 Å²	78.3	30%	0.304	40%	0.402	S	S	.	.	H	α-helix	trans	-58.9	-40.6	175	-69.7	0	0	0	0	112.3	Y241 G249	Y241-C245 PolarHBondContact O-N 3.3Å; Y241-C245 PolarHBondContact O-SG 2.98Å; Y241-C245 VanDerWaalsContact O-SG 3.34Å; C245-G249 PolarHBondContact O-N 2.75Å
246	N	82.9	Confident	81.6	Confident	27 Å²	27	81.2 Å²	81.2	14%	0.144	42%	0.422	C	S	.	.	H	α-helix	trans	-69.3	-35.3	177.5	-77.5	-40.1	0	0	0	112.9	N242 I243 W244 K250 I282	N242-N246 WeakPolarHBondContact O-CB 3.49Å; N242-N246 PolarHBondContact O-N 2.94Å; N242-N246 PolarHBondContact O-ND2 2.95Å; N242-N246 PolarHBondContact OD1-ND2 3.31Å; I243-N246 PolarHBondContact O-N 3.09Å; W244-N246 VanDerWaalsContact C-N 3.31Å; W244-N246 PolarHBondContact O-N 3.19Å; N246-K250 VanDerWaalsContact O-CG 3.3Å; N246-K250 WeakPolarHBondContact O-CG 3.38Å; N246-K250 PolarHBondContact O-N 3.44Å; N246-I282 HydrophobicContact CB-CD1 4.47Å
247	V	82.4	Confident	79.9	Confident	84 Å²	84	86.4 Å²	86.4	51%	0.509	45%	0.445	S	S	.	.	H	α-helix	trans	-69.1	-47.9	174.5	172.3	0	0	0	0	110.2	I243 W244 G249 K250 T251	I243-V247 HydrophobicContact CG2-CG2 4.41Å; I243-V247 WeakPolarHBondContact O-CG2 3.35Å; I243-V247 PolarHBondContact O-N 3.5Å; W244-V247 PolarHBondContact O-N 3.47Å; V247-G249 PolarHBondContact O-N 2.89Å; V247-K250 WeakPolarHBondContact O-CB 3.33Å; V247-K250 PolarHBondContact O-N 2.85Å; V247-K250 VanDerWaalsContact O-N 3.14Å; V247-T251 PolarHBondContact O-N 3.3Å; V247-T251 PolarHBondContact O-OG1 2.88Å
248	R	84	Confident	78.1	Confident	161 Å²	161	86.6 Å²	86.6	61%	0.608	45%	0.447	S	S	*	.	H	α-helix	trans	-60.5	-43.2	178.8	-172.8	174.4	177	175.3	-1.5	112.3	W244 K250 T251 A252	W244-R248 WeakPolarHBondContact O-CB 3.35Å; W244-R248 PolarHBondContact O-N 3.39Å; R248-K250 VanDerWaalsContact C-N 3.3Å; R248-K250 PolarHBondContact O-N 3.18Å; R248-T251 PolarHBondContact O-N 3.43Å; R248-A252 PolarHBondContact O-N 2.87Å
249	G	80	Confident	76.3	Confident	42 Å²	42	84.6 Å²	84.6	43%	0.433	45%	0.452	S	S	.	.	H	α-helix	trans	-62.8	-33.7	175.8	0	0	0	0	0	113.6	C245 V247 S253	C245-G249 PolarHBondContact O-N 2.75Å; V247-G249 PolarHBondContact O-N 2.89Å; G249-S253 WeakPolarHBondContact O-CB 3.47Å; G249-S253 PolarHBondContact O-N 3.2Å
250	K	74.4	Confident	74.4	Confident	99 Å²	99	90.5 Å²	90.5	43%	0.43	48%	0.48	S	S	.	.	H	α-helix	trans	-71.6	-39.3	174.8	-75.9	174.5	179.7	-179.7	0	112.6	N246 V247 R248 R254	N246-K250 VanDerWaalsContact O-CG 3.3Å; N246-K250 WeakPolarHBondContact O-CG 3.38Å; N246-K250 PolarHBondContact O-N 3.44Å; V247-K250 WeakPolarHBondContact O-CB 3.33Å; V247-K250 PolarHBondContact O-N 2.85Å; V247-K250 VanDerWaalsContact O-N 3.14Å; R248-K250 VanDerWaalsContact C-N 3.3Å; R248-K250 PolarHBondContact O-N 3.18Å; K250-R254 WeakPolarHBondContact O-CB 3.37Å; K250-R254 WeakPolarHBondContact O-CG 3.18Å; K250-R254 PolarHBondContact O-N 3.46Å
251	T	75.4	Confident	72.5	Confident	85 Å²	85	94.5 Å²	94.5	52%	0.521	49%	0.491	S	S	.	.	H	α-helix	trans	-65.3	-44.4	176.4	-53	0	0	0	0	110.9	V247 R248 R254 Q255	V247-T251 PolarHBondContact O-N 3.3Å; V247-T251 PolarHBondContact O-OG1 2.88Å; R248-T251 PolarHBondContact O-N 3.43Å; T251-R254 PolarHBondContact O-N 3.36Å; T251-Q255 PolarHBondContact O-N 3.31Å
252	A	75.3	Confident	70.6	Confident	57 Å²	57	91.7 Å²	91.7	47%	0.471	50%	0.499	S	S	.	.	H	α-helix	trans	-63	-43.9	176.6	0	0	0	0	0	112.7	R248 R254 Q255 S256	R248-A252 PolarHBondContact O-N 2.87Å; A252-R254 VanDerWaalsContact C-N 3.35Å; A252-R254 PolarHBondContact O-N 3.06Å; A252-Q255 PolarHBondContact O-N 2.96Å; A252-S256 PolarHBondContact O-N 3.15Å
253	S	66.5	Low	68.6	Low	59 Å²	59	92.8 Å²	92.8	41%	0.413	52%	0.519	S	S	.	.	H	α-helix	trans	-66.3	-34.4	177.6	-178.2	0	0	0	0	112.9	G249 K257	G249-S253 WeakPolarHBondContact O-CB 3.47Å; G249-S253 PolarHBondContact O-N 3.2Å; S253-K257 WeakPolarHBondContact O-CG 3.37Å; S253-K257 PolarHBondContact O-N 2.87Å; S253-K257 VanDerWaalsContact O-N 3.13Å
254	R	64.3	Low	66.9	Low	207 Å²	207	95.1 Å²	95.1	78%	0.781	54%	0.535	S	S	*	.	H	α-helix	trans	-67.1	-39.9	173.8	-83.6	-177.8	161.9	-172.3	-7.6	112.3	K250 T251 A252 K257 G258	K250-R254 WeakPolarHBondContact O-CB 3.37Å; K250-R254 WeakPolarHBondContact O-CG 3.18Å; K250-R254 PolarHBondContact O-N 3.46Å; T251-R254 PolarHBondContact O-N 3.36Å; A252-R254 VanDerWaalsContact C-N 3.35Å; A252-R254 PolarHBondContact O-N 3.06Å; R254-K257 PolarHBondContact O-N 3.34Å; R254-G258 PolarHBondContact O-N 2.72Å
255	Q	61	Low	64.9	Low	150 Å²	150	93.3 Å²	93.3	70%	0.701	55%	0.55	S	S	*	*	H	α-helix	trans	-67.4	-40.6	178.4	-164.6	171.3	3.4	0	0	111.7	T251 A252 G258 A259	T251-Q255 PolarHBondContact O-N 3.31Å; A252-Q255 PolarHBondContact O-N 2.96Å; Q255-G258 PolarHBondContact O-N 3.07Å; Q255-A259 PolarHBondContact O-N 3.34Å
256	S	59.5	Low	62.8	Low	75 Å²	75	100.4 Å²	100.4	52%	0.524	58%	0.576	S	S	.	*	H	α-helix	trans	-62.1	-44	174.5	-165.8	0	0	0	0	112.2	A252 A259 E260	A252-S256 PolarHBondContact O-N 3.15Å; S256-A259 PolarHBondContact O-N 2.95Å; S256-E260 WeakPolarHBondContact O-CB 3.42Å; S256-E260 PolarHBondContact O-N 3.04Å; S256-E260 VanDerWaalsContact O-N 3.14Å
257	K	58.9	Low	60.9	Low	122 Å²	122	107.3 Å²	107.3	53%	0.53	61%	0.608	S	S	.	*	H	α-helix	trans	-70	-32.4	179.1	-72.3	-175.4	177.4	-170.2	0	113.6	S253 R254 Q261	S253-K257 WeakPolarHBondContact O-CG 3.37Å; S253-K257 PolarHBondContact O-N 2.87Å; S253-K257 VanDerWaalsContact O-N 3.13Å; R254-K257 PolarHBondContact O-N 3.34Å; K257-Q261 WeakPolarHBondContact O-CB 3.44Å; K257-Q261 WeakPolarHBondContact O-CG 3.28Å; K257-Q261 PolarHBondContact O-N 3.15Å
258	G	55.4	Low	58.8	Low	46 Å²	46	113.4 Å²	113.4	47%	0.474	63%	0.627	S	S	.	*	H	α-helix	trans	-69.4	-34	176.3	0	0	0	0	0	113.3	R254 Q255	R254-G258 PolarHBondContact O-N 2.72Å; Q255-G258 PolarHBondContact O-N 3.07Å
259	A	56.4	Low	56.5	Low	74 Å²	74	109.3 Å²	109.3	61%	0.612	64%	0.635	S	S	*	*	H	α-helix	trans	-74.4	-38.7	174.6	0	0	0	0	0	112.2	Q255 S256 A262	Q255-A259 PolarHBondContact O-N 3.34Å; S256-A259 PolarHBondContact O-N 2.95Å; A259-A262 PolarHBondContact O-N 3.49Å
260	E	52.5	Low	54.4	Low	125 Å²	125	116.1 Å²	116.1	58%	0.584	65%	0.653	S	S	*	*	H	α-helix	trans	-73	-32.7	-179.7	-143.9	171.6	-175.7	0	0	112.3	S256 A262 G263 V264	S256-E260 WeakPolarHBondContact O-CB 3.42Å; S256-E260 PolarHBondContact O-N 3.04Å; S256-E260 VanDerWaalsContact O-N 3.14Å; E260-A262 VanDerWaalsContact C-N 3.29Å; E260-A262 PolarHBondContact O-N 3.39Å; E260-G263 PolarHBondContact O-N 3.22Å; E260-V264 HydrophobicContact CG-CG2 4.23Å; E260-V264 WeakPolarHBondContact O-CB 3.46Å; E260-V264 VanDerWaalsContact O-CG2 3.22Å; E260-V264 WeakPolarHBondContact O-CG2 3.45Å; E260-V264 PolarHBondContact O-N 3.47Å
261	Q	50.7	Low	52.5	Low	156 Å²	156	118 Å²	118	73%	0.729	67%	0.667	S	S	*	*	H	α-helix	trans	-69.5	-21.2	174.5	-81.7	177.3	-34.4	0	0	114.1	K257	K257-Q261 WeakPolarHBondContact O-CB 3.44Å; K257-Q261 WeakPolarHBondContact O-CG 3.28Å; K257-Q261 PolarHBondContact O-N 3.15Å
262	A	50.8	Low	50.8	Low	90 Å²	90	122.3 Å²	122.3	74%	0.744	69%	0.686	S	S	*	*	H	α-helix	trans	-78.3	-22.4	173.5	0	0	0	0	0	113	A259 E260	A259-A262 PolarHBondContact O-N 3.49Å; E260-A262 VanDerWaalsContact C-N 3.29Å; E260-A262 PolarHBondContact O-N 3.39Å
263	G	47.8	Very low	49.1	Very low	63 Å²	63	123.1 Å²	123.1	65%	0.649	69%	0.693	S	S	*	*	H	α-helix	trans	-102	-15.1	-178.1	0	0	0	0	0	115.9	E260	E260-G263 PolarHBondContact O-N 3.22Å
264	V	51.8	Low	47.7	Very low	91 Å²	91	126.6 Å²	126.6	55%	0.552	71%	0.714	S	S	*	*			trans	-116.1	18.3	-165.5	-170.8	0	0	0	0	113.6	E260 F266	E260-V264 HydrophobicContact CG-CG2 4.23Å; E260-V264 WeakPolarHBondContact O-CB 3.46Å; E260-V264 VanDerWaalsContact O-CG2 3.22Å; E260-V264 WeakPolarHBondContact O-CG2 3.45Å; E260-V264 PolarHBondContact O-N 3.47Å; V264-F266 PolarHBondContact O-N 3.29Å
265	A	45.7	Very low	46.5	Very low	102 Å²	102	121.8 Å²	121.8	84%	0.843	71%	0.711	S	S	*	*	T	Hydrogen-bonded Turn	trans	-67.2	2.4	170.4	0	0	0	0	0	114.2
266	F	43.5	Very low	45.5	Very low	193 Å²	193	120.8 Å²	120.8	85%	0.846	72%	0.715	S	S	*	*	T	Hydrogen-bonded Turn	trans	-114.1	0.8	-171.9	-161.8	-105	0	0	0	116.6	V264	V264-F266 PolarHBondContact O-N 3.29Å
267	Q	43.4	Very low	44.6	Very low	173 Å²	173	121.9 Å²	121.9	81%	0.808	72%	0.722	S	S	*	*			trans	-132.1	93.5	178.1	-115.9	171.4	-9.9	0	0	113.8	G269	Q267-G269 PolarHBondContact O-N 2.87Å
268	K	37.1	Very low	43.9	Very low	212 Å²	212	121 Å²	121	92%	0.922	73%	0.731	S	S	*	*			trans	-54.8	126.8	158.6	-92	175.1	170.7	173.9	0	110
269	G	36.5	Very low	43.7	Very low	74 Å²	74	123.2 Å²	123.2	76%	0.763	74%	0.736	S	S	*	*			trans	86	80.1	139.2	0	0	0	0	0	117.2	Q267	Q267-G269 PolarHBondContact O-N 2.87Å
270	F	36.1	Very low	43.7	Very low	186 Å²	186	127 Å²	127	82%	0.816	74%	0.738	S	S	*	*			trans	-163.8	115	139.9	-154	-115.8	0	0	0	111.4
271	L	34.8	Very low	44.3	Very low	139 Å²	139	124.9 Å²	124.9	73%	0.728	74%	0.737	S	S	*	*			trans	26.9	95.2	150.1	-54.6	180	0	0	0	118.9
272	L	39.7	Very low	45.4	Very low	175 Å²	175	119 Å²	119	92%	0.916	71%	0.71	S	S	*	*			trans	-141.2	121.5	151.9	-82.7	178.2	0	0	0	110.7
273	A	38.3	Very low	46.7	Very low	74 Å²	74	117.7 Å²	117.7	61%	0.612	70%	0.696	S	S	*	*			trans	-51.8	146.7	-179.4	0	0	0	0	0	112.6	C275	A273-C275 PolarHBondContact O-N 3.35Å
274	P	37.6	Very low	48.3	Very low	131 Å²	131	125.7 Å²	125.7	85%	0.851	71%	0.707	S	S	*	*			trans	-72.3	84.2	169.3	30.2	-30.2	0	0	0	108.4	V276	P274-V276 PolarHBondContact O-N 2.89Å
275	C	39.2	Very low	49.6	Very low	107 Å²	107	124.3 Å²	124.3	72%	0.723	71%	0.705	S	S	*	*			trans	-57	125.5	177.5	-70.2	0	0	0	0	110.6	A273 S277	A273-C275 PolarHBondContact O-N 3.35Å; C275-S277 PolarHBondContact O-N 3.14Å
276	V	40.2	Very low	51.3	Low	129 Å²	129	123 Å²	123	78%	0.782	68%	0.68	S	S	*	*			trans	-51.1	93.6	-178.8	-178.1	0	0	0	0	111.6	P274 V279	P274-V276 PolarHBondContact O-N 2.89Å; V276-V279 HydrophobicContact CG1-CG2 4.04Å
277	S	40.3	Very low	53.2	Low	98 Å²	98	116.5 Å²	116.5	69%	0.685	65%	0.654	S	S	*	*			trans	-114.9	4.2	170.8	52.8	0	0	0	0	113.5	C275 V279	C275-S277 PolarHBondContact O-N 3.14Å; S277-V279 PolarHBondContact O-N 2.88Å
278	S	44.7	Very low	55.2	Low	103 Å²	103	114.3 Å²	114.3	72%	0.72	64%	0.638	S	S	*	*	G	3₁₀ helix	trans	-71.6	-10.2	-175	-163.8	0	0	0	0	114.8	K280	S278-K280 PolarHBondContact O-N 3.21Å
279	V	50.5	Low	57.5	Low	93 Å²	93	105.6 Å²	105.6	56%	0.564	60%	0.602	S	S	*	*	G	3₁₀ helix	trans	-81.8	-5.6	-169.3	-164.4	0	0	0	0	114.2	V276 S277	V276-V279 HydrophobicContact CG1-CG2 4.04Å; S277-V279 PolarHBondContact O-N 2.88Å
280	K	55.7	Low	60	Low	152 Å²	152	102.6 Å²	102.6	66%	0.661	57%	0.57	S	S	*	*	G	3₁₀ helix	trans	-104.9	12.1	-178	-70.3	-175.5	-179.4	177.5	0	115.6	S278 I282	S278-K280 PolarHBondContact O-N 3.21Å; K280-I282 PolarHBondContact O-N 3.48Å
281	S	65.4	Low	62.6	Low	82 Å²	82	99.8 Å²	99.8	57%	0.573	56%	0.557	S	S	*	*			trans	-85.8	104.2	174.2	72.4	0	0	0	0	111.7	S283	S281-S283 PolarHBondContact O-N 3.44Å
282	I	74.4	Confident	65.2	Low	31 Å²	31	93.4 Å²	93.4	16%	0.159	52%	0.523	C	S	.	.			trans	-66.5	117	167.9	-55.4	175.5	0	0	0	108	V153 I243 N246 K280 K286 I287	V153-I282 HydrophobicContact CG1-CD1 4.04Å; I243-I282 HydrophobicContact CB-CD1 4.48Å; I243-I282 HydrophobicContact CG1-CD1 3.75Å; N246-I282 HydrophobicContact CB-CD1 4.47Å; K280-I282 PolarHBondContact O-N 3.48Å; I282-K286 HydrophobicContact CG2-CB 3.92Å; I282-K286 HydrophobicContact CG2-CD 4.39Å; I282-I287 HydrophobicContact CB-CG1 4.49Å; I282-I287 HydrophobicContact CG2-CD1 4.23Å; I282-I287 HydrophobicContact CG2-CG1 3.67Å
283	S	78.9	Confident	67.5	Low	64 Å²	64	85 Å²	85	45%	0.448	48%	0.48	S	S	.	.			trans	-59.8	143.2	177.5	169.7	0	0	0	0	111.8	S281 A285 K286 I287	S281-S283 PolarHBondContact O-N 3.44Å; S283-A285 PolarHBondContact O-N 3.08Å; S283-A285 VanDerWaalsContact O-N 3.16Å; S283-A285 PolarHBondContact OG-N 2.8Å; S283-K286 WeakPolarHBondContact O-CB 3.48Å; S283-K286 PolarHBondContact O-N 3.25Å; S283-I287 PolarHBondContact O-N 3.47Å
284	R	80.8	Confident	70.1	Confident	230 Å²	230	86.3 Å²	86.3	87%	0.868	47%	0.471	S	S	*	.	H	α-helix	trans	-52.7	-36	174	-67.4	-175	178.2	-158.1	0	112.1	K286 I287 R288	R284-K286 PolarHBondContact O-N 3.45Å; R284-I287 PolarHBondContact O-N 3.31Å; R284-R288 PolarHBondContact O-N 3.03Å
285	A	78.2	Confident	72.8	Confident	62 Å²	62	82.7 Å²	82.7	51%	0.512	45%	0.447	S	S	.	.	H	α-helix	trans	-63.6	-39.5	176.7	0	0	0	0	0	112.3	S283 R288 T289	S283-A285 PolarHBondContact O-N 3.08Å; S283-A285 VanDerWaalsContact O-N 3.16Å; S283-A285 PolarHBondContact OG-N 2.8Å; A285-R288 PolarHBondContact O-N 3.28Å; A285-T289 WeakPolarHBondContact O-CG2 3.25Å; A285-T289 PolarHBondContact O-N 2.97Å; A285-T289 VanDerWaalsContact O-N 3.17Å
286	K	81.7	Confident	75.3	Confident	75 Å²	75	77.6 Å²	77.6	33%	0.326	41%	0.413	S	S	.	.	H	α-helix	trans	-65	-46.2	175.7	-69.5	-172.9	177.6	-172.5	0	111	A152 I282 S283 R284 R288 T289 V290	A152-K286 PolarHBondContact O-NZ 3.37Å; I282-K286 HydrophobicContact CG2-CB 3.92Å; I282-K286 HydrophobicContact CG2-CD 4.39Å; S283-K286 WeakPolarHBondContact O-CB 3.48Å; S283-K286 PolarHBondContact O-N 3.25Å; R284-K286 PolarHBondContact O-N 3.45Å; K286-R288 VanDerWaalsContact C-N 3.3Å; K286-R288 PolarHBondContact O-N 3.24Å; K286-T289 PolarHBondContact O-N 3.23Å; K286-T289 VanDerWaalsContact O-N 3.14Å; K286-T289 PolarHBondContact O-OG1 3.39Å; K286-V290 WeakPolarHBondContact O-CG2 3.39Å; K286-V290 PolarHBondContact O-N 3.27Å
287	I	83.8	Confident	77.7	Confident	57 Å²	57	71.7 Å²	71.7	29%	0.292	38%	0.377	S	S	.	.	H	α-helix	trans	-60.3	-42.5	178.4	-62	175.5	0	0	0	110.6	I282 S283 R284 T289 V290 K291	I282-I287 HydrophobicContact CB-CG1 4.49Å; I282-I287 HydrophobicContact CG2-CD1 4.23Å; I282-I287 HydrophobicContact CG2-CG1 3.67Å; S283-I287 PolarHBondContact O-N 3.47Å; R284-I287 PolarHBondContact O-N 3.31Å; I287-T289 VanDerWaalsContact C-N 3.3Å; I287-T289 PolarHBondContact O-N 3.37Å; I287-V290 PolarHBondContact O-N 3.37Å; I287-K291 HydrophobicContact CG2-CD 4.35Å; I287-K291 HydrophobicContact CG2-CG 4.36Å; I287-K291 WeakPolarHBondContact O-CG 3.34Å; I287-K291 PolarHBondContact O-N 3.08Å
288	R	85.9	Confident	80.2	Confident	126 Å²	126	69.9 Å²	69.9	48%	0.475	36%	0.362	S	S	.	.	H	α-helix	trans	-56.3	-45.4	175.6	-173.8	177.2	-177.7	168.5	5.7	111.7	R284 A285 K286 K291 M292 F351	R284-R288 PolarHBondContact O-N 3.03Å; A285-R288 PolarHBondContact O-N 3.28Å; K286-R288 VanDerWaalsContact C-N 3.3Å; K286-R288 PolarHBondContact O-N 3.24Å; R288-K291 PolarHBondContact O-N 3.25Å; R288-M292 PolarHBondContact O-N 3.22Å; R288-F351 PolarHBondContact NE-O 2.81Å; R288-F351 PolarHBondContact NH2-O 3.39Å
289	T	85.3	Confident	82.6	Confident	29 Å²	29	65.9 Å²	65.9	18%	0.178	34%	0.335	C	S	.	.	H	α-helix	trans	-67.1	-36.8	177.7	61.3	0	0	0	0	113.5	M86 R149 A285 K286 I287 M292 T293	M86-T289 VanDerWaalsContact CE-CB 3.44Å; M86-T289 HydrophobicContact CE-CG2 3.63Å; R149-T289 PolarHBondContact NH1-OG1 3.44Å; A285-T289 WeakPolarHBondContact O-CG2 3.25Å; A285-T289 PolarHBondContact O-N 2.97Å; A285-T289 VanDerWaalsContact O-N 3.17Å; K286-T289 PolarHBondContact O-N 3.23Å; K286-T289 VanDerWaalsContact O-N 3.14Å; K286-T289 PolarHBondContact O-OG1 3.39Å; I287-T289 VanDerWaalsContact C-N 3.3Å; I287-T289 PolarHBondContact O-N 3.37Å; T289-M292 WeakPolarHBondContact O-CB 3.34Å; T289-M292 PolarHBondContact O-N 3.46Å; T289-T293 WeakPolarHBondContact O-CG2 3.35Å; T289-T293 PolarHBondContact O-N 3.35Å; T289-T293 PolarHBondContact O-OG1 2.86Å
290	V	88.5	Confident	84.6	Confident	12 Å²	12	61.6 Å²	61.6	7%	0.073	31%	0.309	C	S	.	.	H	α-helix	trans	-65.8	-43	175.8	170.8	0	0	0	0	110.8	R149 V153 Y236 I239 K286 I287 M292 T293 F294	R149-V290 HydrophobicContact CB-CG2 4.43Å; V153-V290 HydrophobicContact CG2-CG2 3.81Å; Y236-V290 HydrophobicContact CE1-CG1 4.39Å; I239-V290 HydrophobicContact CG2-CG1 3.65Å; I239-V290 HydrophobicContact CG2-CG2 4.39Å; K286-V290 WeakPolarHBondContact O-CG2 3.39Å; K286-V290 PolarHBondContact O-N 3.27Å; I287-V290 PolarHBondContact O-N 3.37Å; V290-M292 VanDerWaalsContact C-N 3.34Å; V290-M292 PolarHBondContact O-N 3.33Å; V290-T293 PolarHBondContact O-N 2.91Å; V290-T293 PolarHBondContact O-OG1 2.98Å; V290-T293 VanDerWaalsContact O-OG1 3.05Å; V290-F294 VanDerWaalsContact O-CB 3.3Å; V290-F294 WeakPolarHBondContact O-CB 3.34Å; V290-F294 PolarHBondContact O-N 3.25Å
291	K	89.7	Confident	86.5	Confident	127 Å²	127	57 Å²	57	55%	0.552	29%	0.291	S	S	*	.	H	α-helix	trans	-61.2	-44.1	175.5	-72.1	-174.7	175.3	-168.6	0	111.3	I287 R288 F294 V295 F351	I287-K291 HydrophobicContact CG2-CD 4.35Å; I287-K291 HydrophobicContact CG2-CG 4.36Å; I287-K291 WeakPolarHBondContact O-CG 3.34Å; I287-K291 PolarHBondContact O-N 3.08Å; R288-K291 PolarHBondContact O-N 3.25Å; K291-F294 PolarHBondContact O-N 2.92Å; K291-V295 WeakPolarHBondContact O-CG2 3.23Å; K291-V295 PolarHBondContact O-N 3.3Å; K291-F351 HydrophobicContact CB-CE1 3.7Å; K291-F351 HydrophobicContact CB-CZ 4.39Å
292	M	89.5	Confident	87.9	Confident	4 Å²	4	57.5 Å²	57.5	2%	0.02	29%	0.29	C	S	.	.	H	α-helix	trans	-57.6	-53.5	175.9	-175.8	-175.2	86.3	0	0	111.3	M86 I90 R288 T289 V290 F294 V295 I296 I347 Y348 F351	M86-M292 HydrophobicContact CE-CE 3.9Å; M86-M292 HydrophobicContact CG-CE 4.39Å; M86-M292 HydrophobicContact SD-CE 3.91Å; I90-M292 HydrophobicContact CD1-CE 4.22Å; I90-M292 HydrophobicContact CG1-CE 4.47Å; R288-M292 PolarHBondContact O-N 3.22Å; T289-M292 WeakPolarHBondContact O-CB 3.34Å; T289-M292 PolarHBondContact O-N 3.46Å; V290-M292 VanDerWaalsContact C-N 3.34Å; V290-M292 PolarHBondContact O-N 3.33Å; M292-F294 VanDerWaalsContact C-N 3.25Å; M292-F294 PolarHBondContact O-N 3.46Å; M292-V295 PolarHBondContact O-N 3.48Å; M292-I296 HydrophobicContact CG-CD1 4.34Å; M292-I296 WeakPolarHBondContact O-CG1 3.36Å; M292-I296 PolarHBondContact O-N 3.43Å; M292-I296 VanDerWaalsContact O-N 3.15Å; M292-I347 HydrophobicContact CG-CG2 4.04Å; M292-Y348 HydrophobicContact CE-CD1 4.08Å; M292-Y348 HydrophobicContact CE-CE1 4.01Å; M292-Y348 HydrophobicContact SD-CD1 3.87Å; M292-Y348 HydrophobicContact SD-CE1 4.36Å; M292-F351 HydrophobicContact CB-CB 3.68Å; M292-F351 HydrophobicContact CB-CD1 3.71Å; M292-F351 HydrophobicContact CB-CD2 4.22Å; M292-F351 HydrophobicContact CB-CE1 4.41Å; M292-F351 HydrophobicContact CB-CG 3.59Å; M292-F351 HydrophobicContact CG-CB 3.49Å; M292-F351 VanDerWaalsContact CG-CB 3.49Å; M292-F351 HydrophobicContact CG-CD1 4.39Å; M292-F351 HydrophobicContact CG-CD2 4.14Å; M292-F351 HydrophobicContact CG-CG 3.76Å; M292-F351 HydrophobicContact SD-CB 3.77Å
293	T	89.7	Confident	88.8	Confident	0 Å²	0	56.5 Å²	56.5	0%	0	29%	0.286	C	S	.	.	H	α-helix	trans	-64.9	-32	-178.8	58.9	0	0	0	0	112.1	M86 M145 R149 Y236 T289 V290 I296 V297	M86-T293 HydrophobicContact CE-CG2 4.25Å; M145-T293 HydrophobicContact CE-CG2 3.89Å; M145-T293 HydrophobicContact CG-CG2 3.86Å; M145-T293 HydrophobicContact SD-CG2 3.83Å; R149-T293 HydrophobicContact CG-CG2 3.88Å; Y236-T293 WeakPolarHBondContact OH-CB 3.1Å; Y236-T293 PolarHBondContact OH-O 3.37Å; Y236-T293 PolarHBondContact OH-OG1 2.97Å; T289-T293 WeakPolarHBondContact O-CG2 3.35Å; T289-T293 PolarHBondContact O-N 3.35Å; T289-T293 PolarHBondContact O-OG1 2.86Å; V290-T293 PolarHBondContact O-N 2.91Å; V290-T293 PolarHBondContact O-OG1 2.98Å; V290-T293 VanDerWaalsContact O-OG1 3.05Å; T293-I296 PolarHBondContact O-N 3.03Å; T293-V297 WeakPolarHBondContact O-CB 3.24Å; T293-V297 WeakPolarHBondContact O-CG2 3.5Å; T293-V297 PolarHBondContact O-N 3.26Å
294	F	92.3	Very high	89.5	Confident	100 Å²	100	54.3 Å²	54.3	44%	0.439	27%	0.268	S	S	.	.	H	α-helix	trans	-63.2	-45.3	175.4	179	-96.8	0	0	0	111.2	Y236 V290 K291 M292 I296 V297 T298	Y236-F294 HydrophobicContact CD1-CB 4.49Å; Y236-F294 AromaticContact CD1-CD2 3.97Å; Y236-F294 HydrophobicContact CD1-CD2 3.97Å; Y236-F294 HydrophobicContact CD2-CD2 4.37Å; Y236-F294 HydrophobicContact CE1-CB 3.89Å; Y236-F294 HydrophobicContact CE1-CD2 4.15Å; Y236-F294 HydrophobicContact CG-CD2 4.11Å; Y236-F294 WeakPolarHBondContact OH-CA 3.42Å; Y236-F294 PolarHBondContact OH-N 2.66Å; Y236-F294 VanDerWaalsContact OH-N 3.08Å; V290-F294 VanDerWaalsContact O-CB 3.3Å; V290-F294 WeakPolarHBondContact O-CB 3.34Å; V290-F294 PolarHBondContact O-N 3.25Å; K291-F294 PolarHBondContact O-N 2.92Å; M292-F294 VanDerWaalsContact C-N 3.25Å; M292-F294 PolarHBondContact O-N 3.46Å; F294-I296 VanDerWaalsContact C-N 3.34Å; F294-I296 PolarHBondContact O-N 2.73Å; F294-V297 PolarHBondContact O-N 3.29Å; F294-T298 PolarHBondContact O-N 3.36Å; F294-T298 PolarHBondContact O-OG1 3.01Å; F294-T298 VanDerWaalsContact O-OG1 3.1Å
295	V	93.1	Very high	90.1	Very high	56 Å²	56	44.1 Å²	44.1	34%	0.339	23%	0.233	S	C	.	.	H	α-helix	trans	-60.7	-43.3	176.2	174.6	0	0	0	0	111.4	K291 M292 V297 T298 A299 I347 F351	K291-V295 WeakPolarHBondContact O-CG2 3.23Å; K291-V295 PolarHBondContact O-N 3.3Å; M292-V295 PolarHBondContact O-N 3.48Å; V295-V297 VanDerWaalsContact C-N 3.31Å; V295-V297 PolarHBondContact O-N 3.01Å; V295-T298 PolarHBondContact O-N 3.12Å; V295-A299 PolarHBondContact O-N 2.87Å; V295-I347 HydrophobicContact CB-CG2 4.35Å; V295-I347 HydrophobicContact CG1-CD1 3.98Å; V295-I347 HydrophobicContact CG1-CG1 3.99Å; V295-I347 HydrophobicContact CG1-CG2 4.14Å; V295-F351 HydrophobicContact CB-CE2 4.25Å; V295-F351 HydrophobicContact CG1-CE2 4.5Å; V295-F351 HydrophobicContact CG2-CE2 3.89Å; V295-F351 HydrophobicContact CG2-CZ 3.81Å
296	I	91.7	Very high	90.8	Very high	0 Å²	0	43.2 Å²	43.2	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-59.3	-44.7	176.3	-61.9	171.5	0	0	0	110.8	L142 M145 M292 T293 F294 A299 Y300 I347 Y348	L142-I296 HydrophobicContact CD2-CB 4.49Å; L142-I296 HydrophobicContact CD2-CG2 3.28Å; M145-I296 HydrophobicContact CE-CD1 3.97Å; M145-I296 HydrophobicContact CE-CG2 4.42Å; M292-I296 HydrophobicContact CG-CD1 4.34Å; M292-I296 WeakPolarHBondContact O-CG1 3.36Å; M292-I296 PolarHBondContact O-N 3.43Å; M292-I296 VanDerWaalsContact O-N 3.15Å; T293-I296 PolarHBondContact O-N 3.03Å; F294-I296 VanDerWaalsContact C-N 3.34Å; F294-I296 PolarHBondContact O-N 2.73Å; I296-A299 PolarHBondContact O-N 3.2Å; I296-Y300 PolarHBondContact O-N 3.46Å; I296-I347 HydrophobicContact CB-CD1 4.44Å; I296-I347 HydrophobicContact CD1-CG2 4.29Å; I296-I347 HydrophobicContact CG1-CB 4.24Å; I296-I347 HydrophobicContact CG1-CD1 3.86Å; I296-I347 HydrophobicContact CG1-CG2 3.68Å; I296-Y348 HydrophobicContact CD1-CD1 4.43Å; I296-Y348 HydrophobicContact CD1-CE1 3.56Å
297	V	91.8	Very high	91.3	Very high	5 Å²	5	40.7 Å²	40.7	3%	0.03	21%	0.211	C	C	.	.	H	α-helix	trans	-68.7	-39.4	-178.2	163.3	0	0	0	0	112.1	L232 Y236 T293 F294 V295 Y300 I301	L232-V297 HydrophobicContact CB-CG1 4.01Å; L232-V297 HydrophobicContact CD1-CG1 3.86Å; L232-V297 HydrophobicContact CD1-CG2 4.04Å; L232-V297 HydrophobicContact CD2-CG1 4.47Å; L232-V297 HydrophobicContact CD2-CG2 3.8Å; L232-V297 HydrophobicContact CG-CG1 4.33Å; L232-V297 HydrophobicContact CG-CG2 4.43Å; Y236-V297 HydrophobicContact CD2-CG1 4.3Å; Y236-V297 HydrophobicContact CE2-CB 3.85Å; Y236-V297 HydrophobicContact CE2-CG1 3.84Å; Y236-V297 HydrophobicContact CE2-CG2 3.83Å; T293-V297 WeakPolarHBondContact O-CB 3.24Å; T293-V297 WeakPolarHBondContact O-CG2 3.5Å; T293-V297 PolarHBondContact O-N 3.26Å; F294-V297 PolarHBondContact O-N 3.29Å; V295-V297 VanDerWaalsContact C-N 3.31Å; V295-V297 PolarHBondContact O-N 3.01Å; V297-Y300 PolarHBondContact O-N 3.37Å; V297-I301 HydrophobicContact CG1-CD1 4.17Å; V297-I301 WeakPolarHBondContact O-CG1 3.28Å; V297-I301 PolarHBondContact O-N 3.42Å
298	T	93.2	Very high	91.7	Very high	59 Å²	59	38.2 Å²	38.2	36%	0.362	20%	0.198	S	C	.	.	H	α-helix	trans	-62.6	-43.6	173.8	-58.8	0	0	0	0	111.3	F294 V295 Y300 I301 V302	F294-T298 PolarHBondContact O-N 3.36Å; F294-T298 PolarHBondContact O-OG1 3.01Å; F294-T298 VanDerWaalsContact O-OG1 3.1Å; V295-T298 PolarHBondContact O-N 3.12Å; T298-Y300 VanDerWaalsContact C-N 3.33Å; T298-Y300 PolarHBondContact O-N 3.07Å; T298-I301 PolarHBondContact O-N 2.97Å; T298-V302 HydrophobicContact CG2-CG2 4.33Å; T298-V302 WeakPolarHBondContact O-CG2 3.27Å; T298-V302 PolarHBondContact O-N 3.14Å
299	A	93.7	Very high	92	Very high	20 Å²	20	37.1 Å²	37.1	17%	0.165	20%	0.201	C	C	.	.	H	α-helix	trans	-59.1	-45.6	175.9	0	0	0	0	0	111.2	V295 I296 I301 V302 C303 I347	V295-A299 PolarHBondContact O-N 2.87Å; I296-A299 PolarHBondContact O-N 3.2Å; A299-I301 PolarHBondContact O-N 3.39Å; A299-V302 PolarHBondContact O-N 3.3Å; A299-C303 VanDerWaalsContact O-CB 3.26Å; A299-C303 WeakPolarHBondContact O-CB 3.3Å; A299-C303 PolarHBondContact O-N 3.26Å; A299-C303 PolarHBondContact O-SG 3.47Å; A299-I347 HydrophobicContact CB-CD1 4.48Å
300	Y	94.2	Very high	92.1	Very high	2 Å²	2	36.9 Å²	36.9	1%	0.008	20%	0.198	C	C	.	.	H	α-helix	trans	-57.2	-46.2	175.5	164	-94	0	0	0	112.9	A139 L142 I224 F225 P228 V229 L232 I296 V297 T298 W304 N340	A139-Y300 HydrophobicContact CB-CE2 4.17Å; L142-Y300 HydrophobicContact CD1-CD1 4.31Å; L142-Y300 HydrophobicContact CD1-CD2 3.74Å; L142-Y300 HydrophobicContact CD1-CE2 4.5Å; L142-Y300 HydrophobicContact CD1-CG 3.64Å; I224-Y300 PolarHBondContact O-OH 3.36Å; F225-Y300 WeakPolarHBondContact CA-OH 3.4Å; F225-Y300 HydrophobicContact CD2-CE1 4.45Å; P228-Y300 HydrophobicContact CB-CE1 4.43Å; V229-Y300 HydrophobicContact CG2-CE1 4.05Å; L232-Y300 HydrophobicContact CD1-CD1 4.34Å; L232-Y300 HydrophobicContact CD1-CE1 4.36Å; I296-Y300 PolarHBondContact O-N 3.46Å; V297-Y300 PolarHBondContact O-N 3.37Å; T298-Y300 VanDerWaalsContact C-N 3.33Å; T298-Y300 PolarHBondContact O-N 3.07Å; Y300-W304 AromaticContact CD2-CD1 3.39Å; Y300-W304 HydrophobicContact CD2-CG 4.32Å; Y300-W304 AromaticContact CD2-NE1 3.94Å; Y300-W304 AromaticContact CE2-CD1 3.53Å; Y300-W304 HydrophobicContact CE2-CG 4.12Å; Y300-W304 WeakPolarHBondContact O-CB 3.33Å; Y300-W304 PolarHBondContact O-N 2.97Å; Y300-N340 WeakPolarHBondContact CA-OD1 3.25Å; Y300-N340 PolarHBondContact N-OD1 2.99Å
301	I	94.4	Very high	92	Very high	57 Å²	57	37.2 Å²	37.2	29%	0.292	20%	0.199	S	C	.	.	H	α-helix	trans	-63.6	-48.9	178.5	-66	169.9	0	0	0	110.7	V229 V297 T298 A299 C303 W304 A305	V229-I301 HydrophobicContact CG1-CD1 4.41Å; V229-I301 HydrophobicContact CG2-CD1 4.48Å; V229-I301 HydrophobicContact CG2-CG1 3.97Å; V297-I301 HydrophobicContact CG1-CD1 4.17Å; V297-I301 WeakPolarHBondContact O-CG1 3.28Å; V297-I301 PolarHBondContact O-N 3.42Å; T298-I301 PolarHBondContact O-N 2.97Å; A299-I301 PolarHBondContact O-N 3.39Å; I301-C303 VanDerWaalsContact C-N 3.31Å; I301-C303 PolarHBondContact O-N 3Å; I301-W304 PolarHBondContact O-N 3.24Å; I301-A305 WeakPolarHBondContact O-CB 3.04Å; I301-A305 PolarHBondContact O-N 3.44Å
302	V	94.4	Very high	92	Very high	91 Å²	91	33.5 Å²	33.5	55%	0.552	18%	0.184	S	C	*	.	H	α-helix	trans	-63.6	-38.5	-177.9	171.7	0	0	0	0	111.6	T298 A299 P306	T298-V302 HydrophobicContact CG2-CG2 4.33Å; T298-V302 WeakPolarHBondContact O-CG2 3.27Å; T298-V302 PolarHBondContact O-N 3.14Å; A299-V302 PolarHBondContact O-N 3.3Å; V302-P306 VanDerWaalsContact O-CD 3.28Å; V302-P306 WeakPolarHBondContact O-CD 3.27Å
303	C	93.6	Very high	91.9	Very high	11 Å²	11	40.1 Å²	40.1	7%	0.074	21%	0.209	C	C	.	.	H	α-helix	trans	-72.5	-42.1	-179.9	-74.4	0	0	0	0	112.9	A299 I301 L336 G337 N340	A299-C303 VanDerWaalsContact O-CB 3.26Å; A299-C303 WeakPolarHBondContact O-CB 3.3Å; A299-C303 PolarHBondContact O-N 3.26Å; A299-C303 PolarHBondContact O-SG 3.47Å; I301-C303 VanDerWaalsContact C-N 3.31Å; I301-C303 PolarHBondContact O-N 3Å; C303-L336 WeakPolarHBondContact CB-O 3.18Å; C303-L336 CarbonylContact O-C 3.49Å; C303-G337 WeakPolarHBondContact O-CA 2.96Å; C303-G337 PolarHBondContact O-N 3.15Å; C303-N340 HydrophobicContact CB-CB 3.89Å
304	W	93.3	Very high	91.6	Very high	17 Å²	17	42 Å²	42	6%	0.064	22%	0.222	C	C	.	.	H	α-helix	trans	-93.2	-27	-172.7	-78	102.6	0	0	0	114.8	M135 F225 Y300 I301 F307 F308	M135-W304 HydrophobicContact CE-CE3 4.32Å; M135-W304 HydrophobicContact CE-CH2 3.32Å; M135-W304 HydrophobicContact CE-CZ2 4.24Å; M135-W304 HydrophobicContact CE-CZ3 3.38Å; M135-W304 HydrophobicContact CG-CH2 4.29Å; M135-W304 HydrophobicContact SD-CH2 4.22Å; F225-W304 HydrophobicContact CD2-CB 4.02Å; F225-W304 HydrophobicContact CE2-CB 4.23Å; Y300-W304 AromaticContact CD2-CD1 3.39Å; Y300-W304 HydrophobicContact CD2-CG 4.32Å; Y300-W304 AromaticContact CD2-NE1 3.94Å; Y300-W304 AromaticContact CE2-CD1 3.53Å; Y300-W304 HydrophobicContact CE2-CG 4.12Å; Y300-W304 WeakPolarHBondContact O-CB 3.33Å; Y300-W304 PolarHBondContact O-N 2.97Å; I301-W304 PolarHBondContact O-N 3.24Å; W304-F307 HydrophobicContact CE3-CD1 4.08Å; W304-F307 AromaticContact CZ3-CD1 3.98Å; W304-F307 HydrophobicContact CZ3-CD1 3.98Å; W304-F307 HydrophobicContact CZ3-CE1 4.36Å; W304-F307 PolarHBondContact O-N 2.76Å; W304-F308 HydrophobicContact CB-CD2 4.02Å; W304-F308 HydrophobicContact CB-CE2 4.04Å; W304-F308 AromaticContact CD2-CE2 3.95Å; W304-F308 HydrophobicContact CD2-CE2 3.95Å; W304-F308 HydrophobicContact CE3-CD2 4.06Å; W304-F308 AromaticContact CE3-CE2 3.37Å; W304-F308 HydrophobicContact CE3-CE2 3.37Å; W304-F308 HydrophobicContact CE3-CZ 4.02Å; W304-F308 HydrophobicContact CG-CE2 4.27Å; W304-F308 HydrophobicContact CZ3-CE2 4.1Å; W304-F308 HydrophobicContact CZ3-CZ 4.31Å; W304-F308 VanDerWaalsContact O-CD2 3.31Å; W304-F308 WeakPolarHBondContact O-CD2 3.12Å; W304-F308 PolarHBondContact O-N 2.92Å
305	A	94.6	Very high	91.1	Very high	17 Å²	17	38.4 Å²	38.4	14%	0.14	21%	0.208	C	C	.	.	H	α-helix	trans	-56.3	-46.7	-175.8	0	0	0	0	0	113.1	F225 I301 F307 F308 I309	F225-A305 HydrophobicContact CE1-CB 4.44Å; F225-A305 HydrophobicContact CE2-CB 4Å; F225-A305 HydrophobicContact CZ-CB 3.55Å; I301-A305 WeakPolarHBondContact O-CB 3.04Å; I301-A305 PolarHBondContact O-N 3.44Å; A305-F307 VanDerWaalsContact C-N 3.33Å; A305-F307 PolarHBondContact O-N 3.11Å; A305-F308 PolarHBondContact O-N 3.48Å; A305-I309 HydrophobicContact CB-CD1 4.31Å; A305-I309 WeakPolarHBondContact O-CB 3.38Å; A305-I309 WeakPolarHBondContact O-CD1 3.29Å; A305-I309 WeakPolarHBondContact O-CG1 2.94Å; A305-I309 PolarHBondContact O-N 3.32Å
306	P	93.3	Very high	90.8	Very high	43 Å²	43	42.6 Å²	42.6	28%	0.279	22%	0.218	S	C	.	.	H	α-helix	trans	-59.6	-44.1	-177.9	-27.4	39.5	0	0	0	112.4	V302 I309 I310 T333 L336	V302-P306 VanDerWaalsContact O-CD 3.28Å; V302-P306 WeakPolarHBondContact O-CD 3.27Å; P306-I309 PolarHBondContact O-N 3.22Å; P306-I310 WeakPolarHBondContact O-CD1 3.05Å; P306-I310 WeakPolarHBondContact O-CG1 3.27Å; P306-I310 PolarHBondContact O-N 3.3Å; P306-T333 HydrophobicContact CB-CG2 3.68Å; P306-L336 HydrophobicContact CB-CD2 4.33Å; P306-L336 HydrophobicContact CG-CD2 3.79Å
307	F	90.8	Very high	90.4	Very high	21 Å²	21	45.1 Å²	45.1	9%	0.092	23%	0.231	C	C	.	.	H	α-helix	trans	-60.4	-51	178.5	177.1	-105.6	0	0	0	111.7	W304 A305 I309 I310 Q311 A334	W304-F307 HydrophobicContact CE3-CD1 4.08Å; W304-F307 AromaticContact CZ3-CD1 3.98Å; W304-F307 HydrophobicContact CZ3-CD1 3.98Å; W304-F307 HydrophobicContact CZ3-CE1 4.36Å; W304-F307 PolarHBondContact O-N 2.76Å; A305-F307 VanDerWaalsContact C-N 3.33Å; A305-F307 PolarHBondContact O-N 3.11Å; F307-I309 PolarHBondContact O-N 2.85Å; F307-I310 PolarHBondContact O-N 3.08Å; F307-Q311 HydrophobicContact CD1-CG 4.22Å; F307-Q311 HydrophobicContact CD2-CG 4.09Å; F307-Q311 HydrophobicContact CE1-CG 3.86Å; F307-Q311 HydrophobicContact CE2-CG 3.71Å; F307-Q311 HydrophobicContact CG-CG 4.34Å; F307-Q311 HydrophobicContact CZ-CG 3.59Å; F307-Q311 WeakPolarHBondContact O-CB 3.26Å; F307-Q311 WeakPolarHBondContact O-CG 3.49Å; F307-Q311 PolarHBondContact O-N 3.37Å; F307-A334 HydrophobicContact CD2-CB 3.83Å; F307-A334 HydrophobicContact CE2-CB 3.86Å
308	F	91.8	Very high	89.3	Confident	6 Å²	6	50.1 Å²	50.1	3%	0.026	26%	0.264	C	S	.	.	H	α-helix	trans	-68.9	-33.1	-177.7	-75.9	-65.5	0	0	0	113.2	M135 T221 I224 F225 W304 A305 M312	M135-F308 HydrophobicContact CE-CZ 4.03Å; T221-F308 HydrophobicContact CG2-CB 3.94Å; T221-F308 HydrophobicContact CG2-CD1 3.9Å; T221-F308 HydrophobicContact CG2-CG 4.17Å; T221-F308 WeakPolarHBondContact OG1-CD1 3.22Å; I224-F308 HydrophobicContact CB-CE1 4.42Å; I224-F308 HydrophobicContact CB-CZ 3.8Å; I224-F308 HydrophobicContact CG2-CE2 4.04Å; I224-F308 HydrophobicContact CG2-CZ 3.57Å; F225-F308 HydrophobicContact CB-CB 4.38Å; F225-F308 HydrophobicContact CB-CD1 4.34Å; F225-F308 HydrophobicContact CB-CD2 3.39Å; F225-F308 HydrophobicContact CB-CE2 3.63Å; F225-F308 HydrophobicContact CB-CG 3.78Å; F225-F308 HydrophobicContact CB-CZ 4.2Å; F225-F308 HydrophobicContact CD1-CB 4.07Å; F225-F308 HydrophobicContact CD1-CD2 4.31Å; F225-F308 HydrophobicContact CD1-CG 4.38Å; F225-F308 AromaticContact CD2-CD2 3.83Å; F225-F308 HydrophobicContact CD2-CD2 3.83Å; F225-F308 HydrophobicContact CD2-CE2 4.35Å; F225-F308 HydrophobicContact CG-CB 4.21Å; F225-F308 AromaticContact CG-CD2 3.59Å; F225-F308 HydrophobicContact CG-CD2 3.59Å; F225-F308 HydrophobicContact CG-CE2 4.22Å; F225-F308 HydrophobicContact CG-CG 4.05Å; W304-F308 HydrophobicContact CB-CD2 4.02Å; W304-F308 HydrophobicContact CB-CE2 4.04Å; W304-F308 AromaticContact CD2-CE2 3.95Å; W304-F308 HydrophobicContact CD2-CE2 3.95Å; W304-F308 HydrophobicContact CE3-CD2 4.06Å; W304-F308 AromaticContact CE3-CE2 3.37Å; W304-F308 HydrophobicContact CE3-CE2 3.37Å; W304-F308 HydrophobicContact CE3-CZ 4.02Å; W304-F308 HydrophobicContact CG-CE2 4.27Å; W304-F308 HydrophobicContact CZ3-CE2 4.1Å; W304-F308 HydrophobicContact CZ3-CZ 4.31Å; W304-F308 VanDerWaalsContact O-CD2 3.31Å; W304-F308 WeakPolarHBondContact O-CD2 3.12Å; W304-F308 PolarHBondContact O-N 2.92Å; A305-F308 PolarHBondContact O-N 3.48Å; F308-M312 WeakPolarHBondContact O-CB 3.42Å; F308-M312 VanDerWaalsContact O-CG 3.28Å; F308-M312 WeakPolarHBondContact O-CG 3.35Å; F308-M312 PolarHBondContact O-N 3.03Å
309	I	92.2	Very high	88	Confident	103 Å²	103	55 Å²	55	53%	0.528	28%	0.284	S	S	.	.	H	α-helix	trans	-63.3	-49.3	174.2	-70.1	165.6	0	0	0	110.1	A305 P306 F307 M312 W313	A305-I309 HydrophobicContact CB-CD1 4.31Å; A305-I309 WeakPolarHBondContact O-CB 3.38Å; A305-I309 WeakPolarHBondContact O-CD1 3.29Å; A305-I309 WeakPolarHBondContact O-CG1 2.94Å; A305-I309 PolarHBondContact O-N 3.32Å; P306-I309 PolarHBondContact O-N 3.22Å; F307-I309 PolarHBondContact O-N 2.85Å; I309-M312 PolarHBondContact O-N 3.47Å; I309-W313 WeakPolarHBondContact O-CB 3.15Å; I309-W313 PolarHBondContact O-N 2.92Å
310	I	88.2	Confident	86.5	Confident	23 Å²	23	55.3 Å²	55.3	12%	0.118	29%	0.286	C	S	.	.	H	α-helix	trans	-65.1	-42.3	179.8	-72.7	155.7	0	0	0	111.3	P306 F307 M312 W313 S314 T329 I330 T333	P306-I310 WeakPolarHBondContact O-CD1 3.05Å; P306-I310 WeakPolarHBondContact O-CG1 3.27Å; P306-I310 PolarHBondContact O-N 3.3Å; F307-I310 PolarHBondContact O-N 3.08Å; I310-M312 VanDerWaalsContact C-N 3.33Å; I310-M312 PolarHBondContact O-N 3.18Å; I310-W313 PolarHBondContact O-N 2.65Å; I310-S314 WeakPolarHBondContact O-CB 3.48Å; I310-S314 PolarHBondContact O-N 3.36Å; I310-T329 HydrophobicContact CD1-CG2 3.58Å; I310-T329 HydrophobicContact CG1-CG2 4.42Å; I310-I330 HydrophobicContact CG2-CG1 3.84Å; I310-T333 HydrophobicContact CD1-CG2 3.29Å
311	Q	87.1	Confident	84.7	Confident	20 Å²	20	61.1 Å²	61.1	9%	0.093	32%	0.321	C	S	.	.	H	α-helix	trans	-61.9	-40.5	177.2	-72.5	-71.1	103.2	0	0	112.2	V217 F307 V315	V217-Q311 HydrophobicContact CG1-CB 4.06Å; F307-Q311 HydrophobicContact CD1-CG 4.22Å; F307-Q311 HydrophobicContact CD2-CG 4.09Å; F307-Q311 HydrophobicContact CE1-CG 3.86Å; F307-Q311 HydrophobicContact CE2-CG 3.71Å; F307-Q311 HydrophobicContact CG-CG 4.34Å; F307-Q311 HydrophobicContact CZ-CG 3.59Å; F307-Q311 WeakPolarHBondContact O-CB 3.26Å; F307-Q311 WeakPolarHBondContact O-CG 3.49Å; F307-Q311 PolarHBondContact O-N 3.37Å; Q311-V315 WeakPolarHBondContact O-CG2 3.26Å; Q311-V315 PolarHBondContact O-N 3.39Å
312	M	89.4	Confident	82.7	Confident	48 Å²	48	62 Å²	62	24%	0.236	32%	0.321	C	S	.	.	H	α-helix	trans	-68.4	-42.6	175.3	-72.4	-62.7	-126.4	0	0	111.6	V217 T218 T221 F308 I309 I310 V315 W316	V217-M312 HydrophobicContact CG1-SD 4.13Å; T218-M312 HydrophobicContact CG2-CE 4.1Å; T221-M312 HydrophobicContact CG2-CE 3.6Å; T221-M312 HydrophobicContact CG2-CG 3.76Å; T221-M312 HydrophobicContact CG2-SD 4.12Å; F308-M312 WeakPolarHBondContact O-CB 3.42Å; F308-M312 VanDerWaalsContact O-CG 3.28Å; F308-M312 WeakPolarHBondContact O-CG 3.35Å; F308-M312 PolarHBondContact O-N 3.03Å; I309-M312 PolarHBondContact O-N 3.47Å; I310-M312 VanDerWaalsContact C-N 3.33Å; I310-M312 PolarHBondContact O-N 3.18Å; M312-V315 PolarHBondContact O-N 3.5Å; M312-W316 WeakPolarHBondContact O-CB 3.32Å; M312-W316 VanDerWaalsContact O-CD1 3.3Å; M312-W316 PolarHBondContact O-N 2.68Å; M312-W316 VanDerWaalsContact O-N 3.09Å
313	W	87.9	Confident	80.6	Confident	144 Å²	144	62.4 Å²	62.4	55%	0.545	32%	0.324	S	S	.	.	H	α-helix	trans	-58	-52.4	176.5	-168.3	-16.6	0	0	0	110.6	I309 I310 V315 W316 D317	I309-W313 WeakPolarHBondContact O-CB 3.15Å; I309-W313 PolarHBondContact O-N 2.92Å; I310-W313 PolarHBondContact O-N 2.65Å; W313-V315 PolarHBondContact O-N 2.77Å; W313-W316 PolarHBondContact O-N 2.01Å; W313-D317 VanDerWaalsContact CD1-CB 3.42Å; W313-D317 PolarHBondContact NE1-OD2 2.97Å; W313-D317 WeakPolarHBondContact O-CB 3.48Å; W313-D317 PolarHBondContact O-N 2.89Å
314	S	81.9	Confident	78.6	Confident	39 Å²	39	67.1 Å²	67.1	27%	0.273	35%	0.345	S	S	.	.	H	α-helix	trans	-55.2	-25.1	-178.3	171	0	0	0	0	114.3	I310	I310-S314 WeakPolarHBondContact O-CB 3.48Å; I310-S314 PolarHBondContact O-N 3.36Å
315	V	83.3	Confident	76.7	Confident	25 Å²	25	68.9 Å²	68.9	15%	0.152	36%	0.359	C	S	.	.	H	α-helix	trans	-103.3	-25.9	-172.6	172.5	0	0	0	0	112.9	R214 V217 Q311 M312 W313	R214-V315 HydrophobicContact CB-CG1 3.9Å; R214-V315 HydrophobicContact CG-CG1 3.5Å; R214-V315 PolarHBondContact NE-O 3.42Å; V217-V315 HydrophobicContact CB-CG1 4.34Å; V217-V315 HydrophobicContact CB-CG2 4.1Å; V217-V315 HydrophobicContact CG1-CB 4.5Å; V217-V315 HydrophobicContact CG1-CG2 4.11Å; V217-V315 HydrophobicContact CG2-CG2 3.92Å; Q311-V315 WeakPolarHBondContact O-CG2 3.26Å; Q311-V315 PolarHBondContact O-N 3.39Å; M312-V315 PolarHBondContact O-N 3.5Å; W313-V315 PolarHBondContact O-N 2.77Å
316	W	86.1	Confident	74.8	Confident	144 Å²	144	72.3 Å²	72.3	55%	0.545	37%	0.373	S	S	.	.	H	α-helix	trans	-101.1	-18.4	-178.4	-73.8	101	0	0	0	114.2	R214 T218 M312 W313 P318	R214-W316 HydrophobicContact CB-CZ2 4.42Å; T218-W316 WeakPolarHBondContact OG1-CZ2 3.47Å; T218-W316 PolarHBondContact OG1-NE1 3.45Å; T218-W316 VanDerWaalsContact OG1-NE1 3.1Å; M312-W316 WeakPolarHBondContact O-CB 3.32Å; M312-W316 VanDerWaalsContact O-CD1 3.3Å; M312-W316 PolarHBondContact O-N 2.68Å; M312-W316 VanDerWaalsContact O-N 3.09Å; W313-W316 PolarHBondContact O-N 2.01Å; W316-P318 WeakPolarHBondContact O-CD 2.6Å
317	D	82.7	Confident	73.6	Confident	53 Å²	53	72.1 Å²	72.1	28%	0.283	37%	0.369	S	S	.	.			trans	-96.6	105.7	175.4	-175.1	1.2	0	0	0	111.4	W313 M319 S320	W313-D317 VanDerWaalsContact CD1-CB 3.42Å; W313-D317 PolarHBondContact NE1-OD2 2.97Å; W313-D317 WeakPolarHBondContact O-CB 3.48Å; W313-D317 PolarHBondContact O-N 2.89Å; D317-M319 PolarHBondContact O-N 2.96Å; D317-M319 WeakPolarHBondContact OD1-CB 3.32Å; D317-M319 PolarHBondContact OD1-N 3.47Å; D317-S320 PolarHBondContact O-N 2.81Å; D317-S320 PolarHBondContact O-OG 2.95Å
318	P	68.7	Low	73	Confident	109 Å²	109	74 Å²	74	71%	0.708	38%	0.384	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.7	-20.7	-180	-14.3	30.1	0	0	0	113.5	W316 S320	W316-P318 WeakPolarHBondContact O-CD 2.6Å; P318-S320 VanDerWaalsContact C-N 3.29Å
319	M	66.1	Low	72.5	Confident	161 Å²	161	76.5 Å²	76.5	79%	0.793	40%	0.4	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.7	-8.6	-179	-68	-62.5	-61.3	0	0	112.6	D317 V321	D317-M319 PolarHBondContact O-N 2.96Å; D317-M319 WeakPolarHBondContact OD1-CB 3.32Å; D317-M319 PolarHBondContact OD1-N 3.47Å; M319-V321 PolarHBondContact O-N 3.19Å; M319-V321 VanDerWaalsContact O-N 3.15Å
320	S	62	Low	71.9	Confident	28 Å²	28	73.3 Å²	73.3	20%	0.196	38%	0.383	C	S	.	.			trans	-80.6	102.5	-175.9	71.7	0	0	0	0	110.1	D317 P318 W322	D317-S320 PolarHBondContact O-N 2.81Å; D317-S320 PolarHBondContact O-OG 2.95Å; P318-S320 VanDerWaalsContact C-N 3.29Å; S320-W322 PolarHBondContact O-N 2.88Å
321	V	56	Low	71.4	Confident	124 Å²	124	72.8 Å²	72.8	75%	0.752	38%	0.381	S	S	*	.			trans	-72.8	59.9	171.2	-169.4	0	0	0	0	108.8	M319 T323	M319-V321 PolarHBondContact O-N 3.19Å; M319-V321 VanDerWaalsContact O-N 3.15Å; V321-T323 HydrophobicContact CG1-CG2 4.3Å; V321-T323 PolarHBondContact O-N 2.93Å
322	W	53.9	Low	71.3	Confident	74 Å²	74	76.8 Å²	76.8	28%	0.28	40%	0.402	S	S	.	.			trans	-79.8	82.4	162.9	-58.5	100.7	0	0	0	105.9	S320 E324 N327	S320-W322 PolarHBondContact O-N 2.88Å; W322-E324 VanDerWaalsContact C-N 3.31Å; W322-E324 PolarHBondContact O-N 2.9Å; W322-N327 HydrophobicContact CE3-CB 3.99Å; W322-N327 VanDerWaalsContact CE3-CG 3.47Å; W322-N327 HydrophobicContact CZ3-CB 4.36Å; W322-N327 VanDerWaalsContact CZ3-CG 3.41Å; W322-N327 WeakPolarHBondContact CZ3-ND2 3.29Å
323	T	50.1	Low	71.2	Confident	101 Å²	101	75 Å²	75	62%	0.62	39%	0.394	S	S	*	.			trans	-54.8	100.6	166.6	20.5	0	0	0	0	108.4	V321	V321-T323 HydrophobicContact CG1-CG2 4.3Å; V321-T323 PolarHBondContact O-N 2.93Å
324	E	51.8	Low	71	Confident	109 Å²	109	69.9 Å²	69.9	51%	0.509	38%	0.382	S	S	.	.	T	Hydrogen-bonded Turn	trans	31.6	96.3	141.1	-57.9	-139	123.5	0	0	115.5	S4 A5 W322 E326	S4-E324 WeakPolarHBondContact CA-OE1 3.12Å; S4-E324 WeakPolarHBondContact CB-OE1 3.47Å; S4-E324 WeakPolarHBondContact OG-CA 3.48Å; S4-E324 WeakPolarHBondContact OG-CB 3.44Å; S4-E324 WeakPolarHBondContact OG-CG 3.28Å; S4-E324 PolarHBondContact OG-OE1 3.37Å; A5-E324 PolarHBondContact N-OE1 3.47Å; W322-E324 VanDerWaalsContact C-N 3.31Å; W322-E324 PolarHBondContact O-N 2.9Å; E324-E326 VanDerWaalsContact C-N 3.26Å; E324-E326 PolarHBondContact O-N 3.49Å
325	S	51.7	Low	71.1	Confident	54 Å²	54	68.9 Å²	68.9	38%	0.378	37%	0.374	S	S	.	.	T	Hydrogen-bonded Turn	trans	67.1	-15.9	160.4	77.5	0	0	0	0	120.4
326	E	55.3	Low	71.4	Confident	89 Å²	89	70.4 Å²	70.4	42%	0.416	38%	0.381	S	S	.	.			trans	-103.1	0.7	-175.3	-63.9	-146.5	120.1	0	0	115.1	R46 N47 E324 P328	R46-E326 WeakPolarHBondContact CA-OE1 3.43Å; N47-E326 PolarHBondContact N-OE1 2.84Å; E324-E326 VanDerWaalsContact C-N 3.26Å; E324-E326 PolarHBondContact O-N 3.49Å; E326-P328 VanDerWaalsContact O-CD 3.23Å; E326-P328 WeakPolarHBondContact O-CD 3.46Å; E326-P328 VanDerWaalsContact O-N 3.17Å
327	N	69.1	Low	71.5	Confident	40 Å²	40	63.6 Å²	63.6	21%	0.214	36%	0.355	C	S	.	.			trans	-71.5	116	-178	-162.5	-62.6	0	0	0	111	W322 T329 I330 T331	W322-N327 HydrophobicContact CE3-CB 3.99Å; W322-N327 VanDerWaalsContact CE3-CG 3.47Å; W322-N327 HydrophobicContact CZ3-CB 4.36Å; W322-N327 VanDerWaalsContact CZ3-CG 3.41Å; W322-N327 WeakPolarHBondContact CZ3-ND2 3.29Å; N327-T329 PolarHBondContact O-N 3.47Å; N327-T329 WeakPolarHBondContact OD1-CB 3.2Å; N327-T329 PolarHBondContact OD1-N 3.4Å; N327-T329 PolarHBondContact OD1-OG1 2.62Å; N327-T329 VanDerWaalsContact OD1-OG1 3.08Å; N327-I330 HydrophobicContact CB-CD1 4.37Å; N327-I330 HydrophobicContact CB-CG1 4.41Å; N327-I330 PolarHBondContact O-N 3.13Å; N327-T331 PolarHBondContact O-N 3.47Å
328	P	77.2	Confident	71.6	Confident	61 Å²	61	61.3 Å²	61.3	40%	0.396	34%	0.343	S	S	.	.	H	α-helix	trans	-57.9	-26.4	-178.4	24.2	-34.7	0	0	0	112.1	L50 E326 T331 I332	L50-P328 HydrophobicContact CD1-CB 4.13Å; L50-P328 HydrophobicContact CD2-CB 4.17Å; E326-P328 VanDerWaalsContact O-CD 3.23Å; E326-P328 WeakPolarHBondContact O-CD 3.46Å; E326-P328 VanDerWaalsContact O-N 3.17Å; P328-T331 PolarHBondContact O-N 3.49Å; P328-I332 HydrophobicContact CB-CD1 4.3Å; P328-I332 VanDerWaalsContact O-CB 3.27Å; P328-I332 WeakPolarHBondContact O-CB 3.44Å; P328-I332 WeakPolarHBondContact O-CD1 3.37Å; P328-I332 WeakPolarHBondContact O-CG1 3.28Å; P328-I332 PolarHBondContact O-N 3.21Å
329	T	81.1	Confident	72.5	Confident	58 Å²	58	59.4 Å²	59.4	36%	0.356	33%	0.327	S	S	.	.	H	α-helix	trans	-63.1	-41.9	176.7	-55	0	0	0	0	112.4	I310 N327 T333	I310-T329 HydrophobicContact CD1-CG2 3.58Å; I310-T329 HydrophobicContact CG1-CG2 4.42Å; N327-T329 PolarHBondContact O-N 3.47Å; N327-T329 WeakPolarHBondContact OD1-CB 3.2Å; N327-T329 PolarHBondContact OD1-N 3.4Å; N327-T329 PolarHBondContact OD1-OG1 2.62Å; N327-T329 VanDerWaalsContact OD1-OG1 3.08Å; T329-T333 WeakPolarHBondContact O-CB 3.38Å; T329-T333 VanDerWaalsContact O-CG2 3.29Å; T329-T333 WeakPolarHBondContact O-CG2 3.23Å; T329-T333 PolarHBondContact O-N 3.06Å; T329-T333 PolarHBondContact O-OG1 3.39Å
330	I	80	Confident	73.6	Confident	36 Å²	36	51.8 Å²	51.8	19%	0.185	29%	0.289	C	S	.	.	H	α-helix	trans	-66.8	-44.7	177.5	-63.1	175	0	0	0	109.6	I310 N327 T333 A334	I310-I330 HydrophobicContact CG2-CG1 3.84Å; N327-I330 HydrophobicContact CB-CD1 4.37Å; N327-I330 HydrophobicContact CB-CG1 4.41Å; N327-I330 PolarHBondContact O-N 3.13Å; I330-T333 PolarHBondContact O-N 3.36Å; I330-T333 PolarHBondContact O-OG1 2.88Å; I330-T333 VanDerWaalsContact O-OG1 3.11Å; I330-A334 WeakPolarHBondContact O-CB 3.46Å; I330-A334 PolarHBondContact O-N 3.43Å
331	T	78.8	Confident	74.8	Confident	12 Å²	12	50.7 Å²	50.7	7%	0.074	28%	0.281	C	S	.	.	H	α-helix	trans	-61.1	-51.5	177.5	-57	0	0	0	0	111.4	L50 E54 N327 P328 T333 A334 L335	L50-T331 HydrophobicContact CD1-CG2 4.44Å; E54-T331 HydrophobicContact CB-CG2 4.06Å; E54-T331 HydrophobicContact CG-CG2 3.93Å; N327-T331 PolarHBondContact O-N 3.47Å; P328-T331 PolarHBondContact O-N 3.49Å; T331-T333 VanDerWaalsContact C-N 3.3Å; T331-T333 PolarHBondContact O-N 2.93Å; T331-A334 PolarHBondContact O-N 2.92Å; T331-L335 HydrophobicContact CG2-CD1 4.08Å; T331-L335 HydrophobicContact CG2-CG 4.41Å; T331-L335 VanDerWaalsContact O-CG 3.26Å; T331-L335 WeakPolarHBondContact O-CG 3.3Å; T331-L335 PolarHBondContact O-N 2.84Å
332	I	83.5	Confident	76.4	Confident	103 Å²	103	45.3 Å²	45.3	53%	0.528	25%	0.249	S	C	.	.	H	α-helix	trans	-58.2	-43.2	180	-70.4	163.5	0	0	0	111.2	P328 L335 L336	P328-I332 HydrophobicContact CB-CD1 4.3Å; P328-I332 VanDerWaalsContact O-CB 3.27Å; P328-I332 WeakPolarHBondContact O-CB 3.44Å; P328-I332 WeakPolarHBondContact O-CD1 3.37Å; P328-I332 WeakPolarHBondContact O-CG1 3.28Å; P328-I332 PolarHBondContact O-N 3.21Å; I332-L335 PolarHBondContact O-N 3.44Å; I332-L336 PolarHBondContact O-N 3.03Å
333	T	86.9	Confident	78.1	Confident	12 Å²	12	43.7 Å²	43.7	7%	0.074	25%	0.249	C	C	.	.	H	α-helix	trans	-73.3	-33.1	-179.8	57.2	0	0	0	0	113	P306 I310 T329 I330 T331 L336 G337	P306-T333 HydrophobicContact CB-CG2 3.68Å; I310-T333 HydrophobicContact CD1-CG2 3.29Å; T329-T333 WeakPolarHBondContact O-CB 3.38Å; T329-T333 VanDerWaalsContact O-CG2 3.29Å; T329-T333 WeakPolarHBondContact O-CG2 3.23Å; T329-T333 PolarHBondContact O-N 3.06Å; T329-T333 PolarHBondContact O-OG1 3.39Å; I330-T333 PolarHBondContact O-N 3.36Å; I330-T333 PolarHBondContact O-OG1 2.88Å; I330-T333 VanDerWaalsContact O-OG1 3.11Å; T331-T333 VanDerWaalsContact C-N 3.3Å; T331-T333 PolarHBondContact O-N 2.93Å; T333-L336 PolarHBondContact O-N 3.32Å; T333-G337 PolarHBondContact O-N 3.23Å; T333-G337 VanDerWaalsContact O-N 3.08Å
334	A	84.7	Confident	79.8	Confident	36 Å²	36	38.9 Å²	38.9	30%	0.298	22%	0.219	S	C	.	.	H	α-helix	trans	-63.7	-42.7	170.2	0	0	0	0	0	111.8	F307 I330 T331 L336 G337 S338	F307-A334 HydrophobicContact CD2-CB 3.83Å; F307-A334 HydrophobicContact CE2-CB 3.86Å; I330-A334 WeakPolarHBondContact O-CB 3.46Å; I330-A334 PolarHBondContact O-N 3.43Å; T331-A334 PolarHBondContact O-N 2.92Å; A334-L336 VanDerWaalsContact C-N 3.34Å; A334-L336 PolarHBondContact O-N 3.19Å; A334-G337 PolarHBondContact O-N 2.93Å; A334-S338 PolarHBondContact O-N 3.11Å; A334-S338 VanDerWaalsContact O-N 3.13Å
335	L	85	Confident	81.4	Confident	17 Å²	17	33.9 Å²	33.9	9%	0.089	20%	0.196	C	C	.	.	H	α-helix	trans	-61.2	-42.6	174.5	-68.2	173.6	0	0	0	111.1	E54 V57 L58 T331 I332 G337 S338 L339	E54-L335 HydrophobicContact CG-CD2 4.38Å; V57-L335 HydrophobicContact CB-CD1 4.11Å; V57-L335 HydrophobicContact CB-CD2 4.12Å; V57-L335 HydrophobicContact CG1-CB 4.24Å; V57-L335 HydrophobicContact CG1-CD1 4.05Å; V57-L335 HydrophobicContact CG1-CD2 3.84Å; V57-L335 HydrophobicContact CG1-CG 4.26Å; V57-L335 HydrophobicContact CG2-CD1 4.4Å; L58-L335 HydrophobicContact CD2-CD2 3.67Å; L58-L335 HydrophobicContact CG-CD2 3.74Å; T331-L335 HydrophobicContact CG2-CD1 4.08Å; T331-L335 HydrophobicContact CG2-CG 4.41Å; T331-L335 VanDerWaalsContact O-CG 3.26Å; T331-L335 WeakPolarHBondContact O-CG 3.3Å; T331-L335 PolarHBondContact O-N 2.84Å; I332-L335 PolarHBondContact O-N 3.44Å; L335-G337 VanDerWaalsContact C-N 3.3Å; L335-G337 PolarHBondContact O-N 3.48Å; L335-S338 WeakPolarHBondContact O-CB 3.24Å; L335-S338 PolarHBondContact O-N 2.97Å; L335-S338 PolarHBondContact O-OG 3.24Å; L335-L339 PolarHBondContact O-N 2.86Å
336	L	89.7	Confident	83	Confident	58 Å²	58	38 Å²	38	30%	0.304	20%	0.204	S	C	.	.	H	α-helix	trans	-59.7	-39.5	175.3	-177.7	62.2	0	0	0	112.4	C303 P306 I332 T333 A334 S338 L339	C303-L336 WeakPolarHBondContact CB-O 3.18Å; C303-L336 CarbonylContact O-C 3.49Å; P306-L336 HydrophobicContact CB-CD2 4.33Å; P306-L336 HydrophobicContact CG-CD2 3.79Å; I332-L336 PolarHBondContact O-N 3.03Å; T333-L336 PolarHBondContact O-N 3.32Å; A334-L336 VanDerWaalsContact C-N 3.34Å; A334-L336 PolarHBondContact O-N 3.19Å; L336-S338 VanDerWaalsContact C-N 3.32Å; L336-S338 PolarHBondContact O-N 3.01Å; L336-L339 HydrophobicContact CD1-CD1 4.2Å; L336-L339 WeakPolarHBondContact O-CB 3.4Å; L336-L339 PolarHBondContact O-N 3.48Å
337	G	87	Confident	84.5	Confident	0 Å²	0	34.5 Å²	34.5	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-61	-39.5	173	0	0	0	0	0	112.7	C303 T333 A334 L335 L339 N340	C303-G337 WeakPolarHBondContact O-CA 2.96Å; C303-G337 PolarHBondContact O-N 3.15Å; T333-G337 PolarHBondContact O-N 3.23Å; T333-G337 VanDerWaalsContact O-N 3.08Å; A334-G337 PolarHBondContact O-N 2.93Å; L335-G337 VanDerWaalsContact C-N 3.3Å; L335-G337 PolarHBondContact O-N 3.48Å; G337-L339 VanDerWaalsContact C-N 3.31Å; G337-L339 PolarHBondContact O-N 3.46Å; G337-N340 VanDerWaalsContact O-CB 3.28Å; G337-N340 WeakPolarHBondContact O-CB 3.21Å; G337-N340 PolarHBondContact O-N 2.87Å
338	S	84.3	Confident	85.1	Confident	6 Å²	6	32.7 Å²	32.7	4%	0.042	18%	0.178	C	C	.	.	H	α-helix	trans	-67.3	-27.7	179.4	74.6	0	0	0	0	113.8	A334 L335 L336 N340 S341	A334-S338 PolarHBondContact O-N 3.11Å; A334-S338 VanDerWaalsContact O-N 3.13Å; L335-S338 WeakPolarHBondContact O-CB 3.24Å; L335-S338 PolarHBondContact O-N 2.97Å; L335-S338 PolarHBondContact O-OG 3.24Å; L336-S338 VanDerWaalsContact C-N 3.32Å; L336-S338 PolarHBondContact O-N 3.01Å; S338-N340 PolarHBondContact O-N 2.91Å; S338-S341 PolarHBondContact O-N 3.45Å
339	L	87.6	Confident	85.2	Confident	68 Å²	68	31.8 Å²	31.8	36%	0.356	17%	0.169	S	C	.	.	T	Hydrogen-bonded Turn	trans	-64.6	-20.6	176.1	-67.7	174.8	0	0	0	113.4	L335 L336 G337 S341 C342 C343	L335-L339 PolarHBondContact O-N 2.86Å; L336-L339 HydrophobicContact CD1-CD1 4.2Å; L336-L339 WeakPolarHBondContact O-CB 3.4Å; L336-L339 PolarHBondContact O-N 3.48Å; G337-L339 VanDerWaalsContact C-N 3.31Å; G337-L339 PolarHBondContact O-N 3.46Å; L339-S341 VanDerWaalsContact C-N 3.25Å; L339-S341 PolarHBondContact O-N 3.47Å; L339-C342 VanDerWaalsContact O-CB 3.31Å; L339-C342 WeakPolarHBondContact O-CB 3.25Å; L339-C342 PolarHBondContact O-N 3.19Å; L339-C343 PolarHBondContact O-N 3.39Å; L339-C343 PolarHBondContact O-SG 3.36Å
340	N	89.7	Confident	85.2	Confident	1 Å²	1	36.5 Å²	36.5	1%	0.005	19%	0.185	C	C	.	.	H	α-helix	trans	-53.6	-42.9	177.9	178.7	60.3	0	0	0	112.3	Y300 C303 G337 S338 C342 C343	Y300-N340 WeakPolarHBondContact CA-OD1 3.25Å; Y300-N340 PolarHBondContact N-OD1 2.99Å; C303-N340 HydrophobicContact CB-CB 3.89Å; G337-N340 VanDerWaalsContact O-CB 3.28Å; G337-N340 WeakPolarHBondContact O-CB 3.21Å; G337-N340 PolarHBondContact O-N 2.87Å; S338-N340 PolarHBondContact O-N 2.91Å; N340-C342 PolarHBondContact O-N 3.11Å; N340-C343 PolarHBondContact O-N 3.3Å
341	S	87.2	Confident	85.1	Confident	5 Å²	5	37.2 Å²	37.2	4%	0.035	19%	0.187	C	C	.	.	H	α-helix	trans	-66.9	-22.8	179.7	-60.9	0	0	0	0	113.1	N69 V100 S338 L339	N69-S341 PolarHBondContact ND2-O 2.8Å; N69-S341 VanDerWaalsContact ND2-O 3.14Å; V100-S341 WeakPolarHBondContact CG1-OG 3.41Å; S338-S341 PolarHBondContact O-N 3.45Å; L339-S341 VanDerWaalsContact C-N 3.25Å; L339-S341 PolarHBondContact O-N 3.47Å
342	C	89.5	Confident	84.6	Confident	11 Å²	11	37.5 Å²	37.5	7%	0.074	19%	0.189	C	C	.	.	H	α-helix	trans	-79.7	-30.5	177.2	-59.9	0	0	0	0	112.3	T61 V64 L339 N340 P345 W346	T61-C342 PolarHBondContact O-SG 2.87Å; T61-C342 VanDerWaalsContact O-SG 3.4Å; V64-C342 HydrophobicContact CG1-CB 3.77Å; L339-C342 VanDerWaalsContact O-CB 3.31Å; L339-C342 WeakPolarHBondContact O-CB 3.25Å; L339-C342 PolarHBondContact O-N 3.19Å; N340-C342 PolarHBondContact O-N 3.11Å; C342-P345 WeakPolarHBondContact O-CD 3.38Å; C342-W346 PolarHBondContact O-NE1 2.92Å
343	C	89.3	Confident	83.8	Confident	41 Å²	41	34.3 Å²	34.3	28%	0.277	18%	0.181	S	C	.	.	H	α-helix	trans	-69.3	-33	-176.2	-65.1	0	0	0	0	113.2	L339 N340 W346 I347	L339-C343 PolarHBondContact O-N 3.39Å; L339-C343 PolarHBondContact O-SG 3.36Å; N340-C343 PolarHBondContact O-N 3.3Å; C343-W346 PolarHBondContact O-N 2.87Å; C343-I347 HydrophobicContact CB-CD1 4.17Å; C343-I347 WeakPolarHBondContact O-CG1 2.81Å; C343-I347 PolarHBondContact O-N 2.72Å; C343-I347 VanDerWaalsContact O-N 3.09Å
344	N	86.5	Confident	83	Confident	0 Å²	0	37.3 Å²	37.3	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-58.2	-50.3	-170	-69	-15.2	0	0	0	114.1	D97 W346 I347 Y348	D97-N344 PolarHBondContact OD2-ND2 3.39Å; N344-W346 VanDerWaalsContact C-N 3.32Å; N344-W346 PolarHBondContact O-N 2.88Å; N344-I347 PolarHBondContact O-N 3.41Å; N344-I347 VanDerWaalsContact O-N 3.14Å; N344-Y348 HydrophobicContact CB-CE2 3.87Å; N344-Y348 WeakPolarHBondContact O-CD2 3.26Å; N344-Y348 WeakPolarHBondContact O-CE2 3.31Å; N344-Y348 PolarHBondContact O-N 3.41Å
345	P	85.1	Confident	82.1	Confident	3 Å²	3	35.9 Å²	35.9	2%	0.019	18%	0.182	C	C	.	.	H	α-helix	trans	-53.1	-44.9	175.4	-28.7	36.3	0	0	0	113.8	V72 C342 I347 Y348 M349	V72-P345 HydrophobicContact CG2-CB 3.94Å; V72-P345 HydrophobicContact CG2-CG 4.35Å; C342-P345 WeakPolarHBondContact O-CD 3.38Å; P345-I347 PolarHBondContact O-N 3.43Å; P345-Y348 PolarHBondContact O-N 2.87Å; P345-M349 WeakPolarHBondContact O-CG 2.97Å; P345-M349 PolarHBondContact O-N 2.98Å
346	W	84.5	Confident	81.2	Confident	142 Å²	142	38.8 Å²	38.8	54%	0.538	20%	0.197	S	C	.	.	H	α-helix	trans	-62.3	-44.6	178.4	-56	103.5	0	0	0	111.3	C342 C343 N344 Y348 M349 F350	C342-W346 PolarHBondContact O-NE1 2.92Å; C343-W346 PolarHBondContact O-N 2.87Å; N344-W346 VanDerWaalsContact C-N 3.32Å; N344-W346 PolarHBondContact O-N 2.88Å; W346-Y348 VanDerWaalsContact C-N 3.32Å; W346-Y348 PolarHBondContact O-N 3.44Å; W346-M349 HydrophobicContact CB-CE 4.47Å; W346-M349 HydrophobicContact CD2-CE 3.74Å; W346-M349 HydrophobicContact CE3-CE 3.29Å; W346-M349 HydrophobicContact CG-CE 4.27Å; W346-M349 HydrophobicContact CZ3-CE 3.74Å; W346-M349 PolarHBondContact O-N 3.39Å; W346-F350 HydrophobicContact CB-CE2 4.41Å; W346-F350 WeakPolarHBondContact O-CD2 3.16Å; W346-F350 PolarHBondContact O-N 2.89Å
347	I	87.2	Confident	80.2	Confident	15 Å²	15	41.5 Å²	41.5	8%	0.077	21%	0.208	C	C	.	.	H	α-helix	trans	-60.8	-42.7	177.7	-61.4	163.7	0	0	0	110.6	M292 V295 I296 A299 C343 N344 P345 M349 F350 F351	M292-I347 HydrophobicContact CG-CG2 4.04Å; V295-I347 HydrophobicContact CB-CG2 4.35Å; V295-I347 HydrophobicContact CG1-CD1 3.98Å; V295-I347 HydrophobicContact CG1-CG1 3.99Å; V295-I347 HydrophobicContact CG1-CG2 4.14Å; I296-I347 HydrophobicContact CB-CD1 4.44Å; I296-I347 HydrophobicContact CD1-CG2 4.29Å; I296-I347 HydrophobicContact CG1-CB 4.24Å; I296-I347 HydrophobicContact CG1-CD1 3.86Å; I296-I347 HydrophobicContact CG1-CG2 3.68Å; A299-I347 HydrophobicContact CB-CD1 4.48Å; C343-I347 HydrophobicContact CB-CD1 4.17Å; C343-I347 WeakPolarHBondContact O-CG1 2.81Å; C343-I347 PolarHBondContact O-N 2.72Å; C343-I347 VanDerWaalsContact O-N 3.09Å; N344-I347 PolarHBondContact O-N 3.41Å; N344-I347 VanDerWaalsContact O-N 3.14Å; P345-I347 PolarHBondContact O-N 3.43Å; I347-M349 PolarHBondContact O-N 2.66Å; I347-F350 PolarHBondContact O-N 3.03Å; I347-F351 HydrophobicContact CG2-CD2 3.83Å; I347-F351 HydrophobicContact CG2-CE2 4.26Å; I347-F351 WeakPolarHBondContact O-CB 3.06Å; I347-F351 WeakPolarHBondContact O-CD2 3.09Å; I347-F351 PolarHBondContact O-N 3.43Å
348	Y	82.8	Confident	79.4	Confident	1 Å²	1	43 Å²	43	0%	0.004	22%	0.216	C	C	.	.	H	α-helix	trans	-64.4	-40.3	176.1	-58.8	-47.8	0	0	0	112.6	V72 I90 L93 M292 I296 N344 P345 W346 F351 S352	V72-Y348 HydrophobicContact CG1-CD2 4.09Å; V72-Y348 HydrophobicContact CG2-CD2 4.03Å; I90-Y348 HydrophobicContact CB-CE1 4.48Å; I90-Y348 HydrophobicContact CD1-CD1 4.05Å; I90-Y348 HydrophobicContact CD1-CE1 4.21Å; I90-Y348 HydrophobicContact CG1-CD1 4.15Å; I90-Y348 HydrophobicContact CG1-CE1 3.81Å; I90-Y348 HydrophobicContact CG2-CD1 4.18Å; I90-Y348 HydrophobicContact CG2-CD2 3.98Å; I90-Y348 HydrophobicContact CG2-CE1 4.04Å; I90-Y348 HydrophobicContact CG2-CE2 3.84Å; I90-Y348 HydrophobicContact CG2-CG 4.17Å; L93-Y348 WeakPolarHBondContact CD2-OH 3.46Å; L93-Y348 WeakPolarHBondContact CG-OH 3.27Å; M292-Y348 HydrophobicContact CE-CD1 4.08Å; M292-Y348 HydrophobicContact CE-CE1 4.01Å; M292-Y348 HydrophobicContact SD-CD1 3.87Å; M292-Y348 HydrophobicContact SD-CE1 4.36Å; I296-Y348 HydrophobicContact CD1-CD1 4.43Å; I296-Y348 HydrophobicContact CD1-CE1 3.56Å; N344-Y348 HydrophobicContact CB-CE2 3.87Å; N344-Y348 WeakPolarHBondContact O-CD2 3.26Å; N344-Y348 WeakPolarHBondContact O-CE2 3.31Å; N344-Y348 PolarHBondContact O-N 3.41Å; P345-Y348 PolarHBondContact O-N 2.87Å; W346-Y348 VanDerWaalsContact C-N 3.32Å; W346-Y348 PolarHBondContact O-N 3.44Å; Y348-F351 PolarHBondContact O-N 3.06Å; Y348-S352 VanDerWaalsContact O-CA 3.32Å; Y348-S352 WeakPolarHBondContact O-CA 3.35Å; Y348-S352 WeakPolarHBondContact O-CB 3.32Å; Y348-S352 PolarHBondContact O-N 2.85Å
349	M	78.2	Confident	78.6	Confident	42 Å²	42	43.4 Å²	43.4	21%	0.207	22%	0.219	C	C	.	.	H	α-helix	trans	-61.7	-44.7	177.8	-73.7	-171.9	-68	0	0	111.6	P345 W346 I347 L356	P345-M349 WeakPolarHBondContact O-CG 2.97Å; P345-M349 PolarHBondContact O-N 2.98Å; W346-M349 HydrophobicContact CB-CE 4.47Å; W346-M349 HydrophobicContact CD2-CE 3.74Å; W346-M349 HydrophobicContact CE3-CE 3.29Å; W346-M349 HydrophobicContact CG-CE 4.27Å; W346-M349 HydrophobicContact CZ3-CE 3.74Å; W346-M349 PolarHBondContact O-N 3.39Å; I347-M349 PolarHBondContact O-N 2.66Å; M349-L356 HydrophobicContact CB-CB 4.45Å; M349-L356 HydrophobicContact CB-CD1 4.24Å
350	F	80.7	Confident	77.8	Confident	158 Å²	158	43.4 Å²	43.4	69%	0.693	22%	0.221	S	C	*	.	H	α-helix	trans	-67.8	-44.3	177.2	-74	-64.2	0	0	0	112.8	W346 I347	W346-F350 HydrophobicContact CB-CE2 4.41Å; W346-F350 WeakPolarHBondContact O-CD2 3.16Å; W346-F350 PolarHBondContact O-N 2.89Å; I347-F350 PolarHBondContact O-N 3.03Å
351	F	78.1	Confident	76.6	Confident	51 Å²	51	46.2 Å²	46.2	22%	0.224	23%	0.234	C	C	.	.	H	α-helix	trans	-86.8	-14.3	-175.7	-80	-89	0	0	0	114	R288 K291 M292 V295 I347 Y348	R288-F351 PolarHBondContact NE-O 2.81Å; R288-F351 PolarHBondContact NH2-O 3.39Å; K291-F351 HydrophobicContact CB-CE1 3.7Å; K291-F351 HydrophobicContact CB-CZ 4.39Å; M292-F351 HydrophobicContact CB-CB 3.68Å; M292-F351 HydrophobicContact CB-CD1 3.71Å; M292-F351 HydrophobicContact CB-CD2 4.22Å; M292-F351 HydrophobicContact CB-CE1 4.41Å; M292-F351 HydrophobicContact CB-CG 3.59Å; M292-F351 HydrophobicContact CG-CB 3.49Å; M292-F351 VanDerWaalsContact CG-CB 3.49Å; M292-F351 HydrophobicContact CG-CD1 4.39Å; M292-F351 HydrophobicContact CG-CD2 4.14Å; M292-F351 HydrophobicContact CG-CG 3.76Å; M292-F351 HydrophobicContact SD-CB 3.77Å; V295-F351 HydrophobicContact CB-CE2 4.25Å; V295-F351 HydrophobicContact CG1-CE2 4.5Å; V295-F351 HydrophobicContact CG2-CE2 3.89Å; V295-F351 HydrophobicContact CG2-CZ 3.81Å; I347-F351 HydrophobicContact CG2-CD2 3.83Å; I347-F351 HydrophobicContact CG2-CE2 4.26Å; I347-F351 WeakPolarHBondContact O-CB 3.06Å; I347-F351 WeakPolarHBondContact O-CD2 3.09Å; I347-F351 PolarHBondContact O-N 3.43Å; Y348-F351 PolarHBondContact O-N 3.06Å
352	S	69.4	Low	75.6	Confident	17 Å²	17	46.7 Å²	46.7	12%	0.119	24%	0.238	C	C	.	.			trans	-128.2	75.9	179.3	-56.7	0	0	0	0	109.4	Y348 H354 L355 L356	Y348-S352 VanDerWaalsContact O-CA 3.32Å; Y348-S352 WeakPolarHBondContact O-CA 3.35Å; Y348-S352 WeakPolarHBondContact O-CB 3.32Å; Y348-S352 PolarHBondContact O-N 2.85Å; S352-H354 PolarHBondContact O-N 3.06Å; S352-L355 WeakPolarHBondContact O-CA 3.09Å; S352-L355 WeakPolarHBondContact O-CB 3.27Å; S352-L355 PolarHBondContact O-N 2.91Å; S352-L356 PolarHBondContact O-N 2.93Å
353	G	66	Low	74.7	Confident	36 Å²	36	51.3 Å²	51.3	37%	0.371	26%	0.257	S	S	.	.	H	α-helix	trans	-53.1	-26.2	-178.4	0	0	0	0	0	114.7	L356 Q357	G353-L356 PolarHBondContact O-N 2.89Å; G353-Q357 PolarHBondContact O-N 3.26Å; G353-Q357 VanDerWaalsContact O-N 3.14Å
354	H	70.5	Confident	73.3	Confident	75 Å²	75	53.8 Å²	53.8	35%	0.347	27%	0.272	S	S	.	.	H	α-helix	trans	-67.7	-37	172.3	84.5	-82.5	0	0	0	112.9	H87 S352 L356 Q357 D358	H87-H354 AromaticContact CE1-CE1 3.99Å; H87-H354 AromaticContact CE1-NE2 3.47Å; H87-H354 PolarHBondContact CE1-NE2 3.48Å; H87-H354 AromaticContact NE2-CE1 3.49Å; H87-H354 PolarHBondContact NE2-CE1 2.81Å; H87-H354 AromaticContact NE2-NE2 3.41Å; H87-H354 PolarHBondContact NE2-NE2 3.08Å; S352-H354 PolarHBondContact O-N 3.06Å; H354-L356 VanDerWaalsContact C-N 3.33Å; H354-Q357 PolarHBondContact O-N 3.43Å; H354-D358 IonicContact CD2-OD2 3.65Å; H354-D358 WeakPolarHBondContact O-CB 3.16Å; H354-D358 VanDerWaalsContact O-CG 3.29Å; H354-D358 PolarHBondContact O-N 2.87Å
355	L	64.7	Low	72.1	Confident	6 Å²	6	58.9 Å²	58.9	3%	0.031	31%	0.307	C	S	.	.	H	α-helix	trans	-69.3	-34.4	176.1	-62.4	-179.3	0	0	0	111.1	L76 I90 S352 Q357 D358 C359	L76-L355 HydrophobicContact CD2-CD1 4.34Å; L76-L355 HydrophobicContact CD2-CD2 3.68Å; L76-L355 HydrophobicContact CG-CD2 4.38Å; I90-L355 HydrophobicContact CD1-CD1 4.41Å; S352-L355 WeakPolarHBondContact O-CA 3.09Å; S352-L355 WeakPolarHBondContact O-CB 3.27Å; S352-L355 PolarHBondContact O-N 2.91Å; L355-Q357 VanDerWaalsContact C-N 3.35Å; L355-D358 PolarHBondContact O-N 3.34Å; L355-C359 WeakPolarHBondContact O-CB 3.09Å; L355-C359 PolarHBondContact O-N 3.34Å
356	L	68.1	Low	70.7	Confident	78 Å²	78	61 Å²	61	41%	0.408	32%	0.321	S	S	.	.	H	α-helix	trans	-61.9	-46.3	172.3	-174.4	152.7	0	0	0	110.1	M349 S352 G353 H354 D358 C359 V360	M349-L356 HydrophobicContact CB-CB 4.45Å; M349-L356 HydrophobicContact CB-CD1 4.24Å; S352-L356 PolarHBondContact O-N 2.93Å; G353-L356 PolarHBondContact O-N 2.89Å; H354-L356 VanDerWaalsContact C-N 3.33Å; L356-D358 PolarHBondContact O-N 2.88Å; L356-C359 PolarHBondContact O-N 2.69Å; L356-V360 HydrophobicContact CD2-CG2 4.06Å; L356-V360 WeakPolarHBondContact O-CB 3.46Å; L356-V360 VanDerWaalsContact O-CG2 3.25Å; L356-V360 WeakPolarHBondContact O-CG2 3.28Å; L356-V360 PolarHBondContact O-N 2.96Å
357	Q	68.2	Low	69.5	Low	116 Å²	116	58.8 Å²	58.8	54%	0.542	32%	0.317	S	S	.	.	H	α-helix	trans	-61.6	-42.8	176.4	-175.9	175.7	3.9	0	0	112.3	G353 H354 L355 Q361	G353-Q357 PolarHBondContact O-N 3.26Å; G353-Q357 VanDerWaalsContact O-N 3.14Å; H354-Q357 PolarHBondContact O-N 3.43Å; L355-Q357 VanDerWaalsContact C-N 3.35Å; Q357-Q361 VanDerWaalsContact CG-NE2 3.31Å; Q357-Q361 WeakPolarHBondContact O-CB 3.27Å; Q357-Q361 VanDerWaalsContact O-CG 3.26Å; Q357-Q361 WeakPolarHBondContact O-CG 3.33Å; Q357-Q361 PolarHBondContact O-N 3.06Å
358	D	69.5	Low	68	Low	32 Å²	32	63.4 Å²	63.4	17%	0.171	34%	0.341	C	S	.	.	H	α-helix	trans	-70	-34.1	178.4	-69.3	-15.6	0	0	0	112.3	A75 T79 H354 L355 L356 S362	A75-D358 HydrophobicContact CB-CB 4.17Å; T79-D358 PolarHBondContact OG1-OD2 3.48Å; H354-D358 IonicContact CD2-OD2 3.65Å; H354-D358 WeakPolarHBondContact O-CB 3.16Å; H354-D358 VanDerWaalsContact O-CG 3.29Å; H354-D358 PolarHBondContact O-N 2.87Å; L355-D358 PolarHBondContact O-N 3.34Å; L356-D358 PolarHBondContact O-N 2.88Å; D358-S362 WeakPolarHBondContact O-CB 3.44Å; D358-S362 PolarHBondContact O-N 2.9Å; D358-S362 VanDerWaalsContact O-N 3.09Å; D358-S362 PolarHBondContact O-OG 3.03Å
359	C	68.9	Low	66.6	Low	14 Å²	14	69.9 Å²	69.9	10%	0.095	37%	0.374	C	S	.	.	H	α-helix	trans	-68.4	-46.5	174.1	-172.4	0	0	0	0	110.9	A75 L355 L356 Q361 S362 F363	A75-C359 HydrophobicContact CB-CB 4.39Å; L355-C359 WeakPolarHBondContact O-CB 3.09Å; L355-C359 PolarHBondContact O-N 3.34Å; L356-C359 PolarHBondContact O-N 2.69Å; C359-Q361 VanDerWaalsContact C-N 3.34Å; C359-Q361 PolarHBondContact O-N 3.42Å; C359-S362 WeakPolarHBondContact O-CA 3.4Å; C359-S362 VanDerWaalsContact O-CB 3.22Å; C359-S362 WeakPolarHBondContact O-CB 3.37Å; C359-S362 PolarHBondContact O-N 3.4Å; C359-F363 WeakPolarHBondContact O-CD2 3.44Å
360	V	69.5	Low	65.4	Low	67 Å²	67	73.1 Å²	73.1	41%	0.406	39%	0.386	S	S	.	.	H	α-helix	trans	-61.1	-43.7	175.2	172.5	0	0	0	0	110.8	L356 S362 F363 C366	L356-V360 HydrophobicContact CD2-CG2 4.06Å; L356-V360 WeakPolarHBondContact O-CB 3.46Å; L356-V360 VanDerWaalsContact O-CG2 3.25Å; L356-V360 WeakPolarHBondContact O-CG2 3.28Å; L356-V360 PolarHBondContact O-N 2.96Å; V360-S362 PolarHBondContact O-N 3.39Å; V360-F363 PolarHBondContact O-N 3.3Å; V360-C366 HydrophobicContact CG1-CB 4.27Å; V360-C366 VanDerWaalsContact O-CB 3.24Å; V360-C366 WeakPolarHBondContact O-CB 3.45Å
361	Q	65.7	Low	64.3	Low	60 Å²	60	72.2 Å²	72.2	28%	0.28	38%	0.384	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.6	-14.6	174.8	-73.5	178.7	38.4	0	0	113.7	Q357 C359 Q367	Q357-Q361 VanDerWaalsContact CG-NE2 3.31Å; Q357-Q361 WeakPolarHBondContact O-CB 3.27Å; Q357-Q361 VanDerWaalsContact O-CG 3.26Å; Q357-Q361 WeakPolarHBondContact O-CG 3.33Å; Q357-Q361 PolarHBondContact O-N 3.06Å; C359-Q361 VanDerWaalsContact C-N 3.34Å; C359-Q361 PolarHBondContact O-N 3.42Å; Q361-Q367 WeakPolarHBondContact O-CG 3.17Å; Q361-Q367 PolarHBondContact O-NE2 2.97Å
362	S	66.2	Low	63.2	Low	16 Å²	16	76.4 Å²	76.4	11%	0.112	40%	0.403	C	S	.	.	T	Hydrogen-bonded Turn	trans	-82	-17.9	177.8	-71.6	0	0	0	0	113.7	R78 D358 C359 V360	R78-S362 PolarHBondContact NH1-O 2.95Å; R78-S362 PolarHBondContact NH1-OG 3.49Å; D358-S362 WeakPolarHBondContact O-CB 3.44Å; D358-S362 PolarHBondContact O-N 2.9Å; D358-S362 VanDerWaalsContact O-N 3.09Å; D358-S362 PolarHBondContact O-OG 3.03Å; C359-S362 WeakPolarHBondContact O-CA 3.4Å; C359-S362 VanDerWaalsContact O-CB 3.22Å; C359-S362 WeakPolarHBondContact O-CB 3.37Å; C359-S362 PolarHBondContact O-N 3.4Å; V360-S362 PolarHBondContact O-N 3.39Å
363	F	68.8	Low	62.4	Low	108 Å²	108	81.8 Å²	81.8	47%	0.474	42%	0.424	S	S	.	.	S	Bend	trans	-78.7	129.6	174.4	-70.7	-79.2	0	0	0	110.5	C359 V360 C365 C366 Q367	C359-F363 WeakPolarHBondContact O-CD2 3.44Å; V360-F363 PolarHBondContact O-N 3.3Å; F363-C365 PolarHBondContact O-N 2.92Å; F363-C365 VanDerWaalsContact O-N 3.14Å; F363-C366 PolarHBondContact O-N 3.41Å; F363-Q367 PolarHBondContact O-N 3Å
364	P	59.9	Low	61.9	Low	93 Å²	93	84.3 Å²	84.3	60%	0.604	43%	0.429	S	S	*	.	H	α-helix	trans	-53.7	-36.2	-177.2	-25.8	32.4	0	0	0	113.9	C366 Q367	P364-C366 PolarHBondContact O-N 3.39Å; P364-Q367 PolarHBondContact O-N 2.87Å
365	C	61.3	Low	61	Low	106 Å²	106	87.9 Å²	87.9	72%	0.716	44%	0.443	S	S	*	.	H	α-helix	trans	-61.4	-28.2	178.2	-63.8	0	0	0	0	113.6	F363	F363-C365 PolarHBondContact O-N 2.92Å; F363-C365 VanDerWaalsContact O-N 3.14Å
366	C	57.3	Low	60.7	Low	47 Å²	47	92.9 Å²	92.9	32%	0.318	47%	0.467	S	S	.	.	H	α-helix	trans	-91.2	-19	-179	-65	0	0	0	0	113.2	V360 F363 P364 M369 K370	V360-C366 HydrophobicContact CG1-CB 4.27Å; V360-C366 VanDerWaalsContact O-CB 3.24Å; V360-C366 WeakPolarHBondContact O-CB 3.45Å; F363-C366 PolarHBondContact O-N 3.41Å; P364-C366 PolarHBondContact O-N 3.39Å; C366-M369 PolarHBondContact O-N 3.3Å; C366-K370 PolarHBondContact O-N 3.43Å
367	Q	58.5	Low	60.1	Low	96 Å²	96	93.1 Å²	93.1	45%	0.449	47%	0.468	S	S	.	.	H	α-helix	trans	-66.5	-41.6	173.1	-67.4	-173.2	-21.1	0	0	110.9	Q361 F363 P364 M369 K370 E371	Q361-Q367 WeakPolarHBondContact O-CG 3.17Å; Q361-Q367 PolarHBondContact O-NE2 2.97Å; F363-Q367 PolarHBondContact O-N 3Å; P364-Q367 PolarHBondContact O-N 2.87Å; Q367-M369 VanDerWaalsContact C-N 3.27Å; Q367-M369 PolarHBondContact O-N 3.31Å; Q367-K370 PolarHBondContact O-N 2.96Å; Q367-E371 PolarHBondContact O-N 3.42Å; Q367-E371 VanDerWaalsContact O-N 3.12Å
368	N	55	Low	59.6	Low	112 Å²	112	92 Å²	92	60%	0.599	47%	0.47	S	S	*	.	H	α-helix	trans	-60.2	-34.8	174.9	-74.8	-13.3	0	0	0	113	K372	N368-K372 WeakPolarHBondContact O-CB 3.38Å; N368-K372 PolarHBondContact O-N 3.08Å; N368-K372 VanDerWaalsContact O-N 3.07Å
369	M	54.4	Low	59.1	Low	138 Å²	138	94.4 Å²	94.4	68%	0.68	48%	0.482	S	S	*	.	H	α-helix	trans	-69.6	-37.3	178.6	-70.6	-83.4	-79.8	0	0	112.1	C366 Q367 K372 F373	C366-M369 PolarHBondContact O-N 3.3Å; Q367-M369 VanDerWaalsContact C-N 3.27Å; Q367-M369 PolarHBondContact O-N 3.31Å; M369-K372 PolarHBondContact O-N 2.79Å; M369-F373 WeakPolarHBondContact O-CB 3.4Å; M369-F373 PolarHBondContact O-N 2.9Å
370	K	53.7	Low	58.6	Low	109 Å²	109	96 Å²	96	47%	0.474	49%	0.494	S	S	.	.	H	α-helix	trans	-73.5	-37.6	179	-169	178.8	-178.1	-176.7	0	112.1	C366 Q367 K372 F373 N374	C366-K370 PolarHBondContact O-N 3.43Å; Q367-K370 PolarHBondContact O-N 2.96Å; K370-K372 VanDerWaalsContact C-N 3.32Å; K370-F373 PolarHBondContact O-N 3.31Å; K370-N374 WeakPolarHBondContact O-CB 3.47Å; K370-N374 PolarHBondContact O-N 3.35Å
371	E	56.7	Low	57.9	Low	140 Å²	140	98.4 Å²	98.4	65%	0.654	50%	0.502	S	S	*	.	H	α-helix	trans	-64.2	-39.8	172.3	-73.3	-173.4	166.2	0	0	111.4	Q367 K375	Q367-E371 PolarHBondContact O-N 3.42Å; Q367-E371 VanDerWaalsContact O-N 3.12Å; E371-K375 VanDerWaalsContact O-CB 3.25Å; E371-K375 WeakPolarHBondContact O-CB 3.46Å; E371-K375 PolarHBondContact O-N 2.87Å
372	K	54.3	Low	57.6	Low	139 Å²	139	98.6 Å²	98.6	60%	0.604	51%	0.51	S	S	*	.	H	α-helix	trans	-65.7	-43.1	176.5	-149.1	174.4	-174.5	-175.5	0	112.2	N368 M369 K370 K375 E376	N368-K372 WeakPolarHBondContact O-CB 3.38Å; N368-K372 PolarHBondContact O-N 3.08Å; N368-K372 VanDerWaalsContact O-N 3.07Å; M369-K372 PolarHBondContact O-N 2.79Å; K370-K372 VanDerWaalsContact C-N 3.32Å; K372-K375 PolarHBondContact O-N 3.32Å; K372-E376 WeakPolarHBondContact O-CG 3.37Å; K372-E376 PolarHBondContact O-N 3.43Å
373	F	53	Low	57.1	Low	130 Å²	130	105.8 Å²	105.8	57%	0.57	54%	0.535	S	S	*	.	H	α-helix	trans	-69.7	-41.6	178.9	-148.7	-91.3	0	0	0	112.7	M369 K370 K375 E376 D377	M369-F373 WeakPolarHBondContact O-CB 3.4Å; M369-F373 PolarHBondContact O-N 2.9Å; K370-F373 PolarHBondContact O-N 3.31Å; F373-K375 VanDerWaalsContact C-N 3.29Å; F373-K375 PolarHBondContact O-N 2.94Å; F373-E376 PolarHBondContact O-N 3.34Å; F373-D377 PolarHBondContact O-N 3.43Å
374	N	54.9	Low	56.5	Low	89 Å²	89	108.9 Å²	108.9	48%	0.476	54%	0.543	S	S	.	.	H	α-helix	trans	-65.1	-34	174.6	-78.2	-19.2	0	0	0	111.9	K370 T378	K370-N374 WeakPolarHBondContact O-CB 3.47Å; K370-N374 PolarHBondContact O-N 3.35Å; N374-T378 WeakPolarHBondContact O-CB 3.31Å; N374-T378 PolarHBondContact O-N 2.84Å; N374-T378 PolarHBondContact O-OG1 3.05Å
375	K	53.6	Low	56.3	Low	149 Å²	149	111 Å²	111	65%	0.648	55%	0.545	S	S	*	.	H	α-helix	trans	-68.7	-41.6	175.3	-167.1	169.3	-178.2	172.2	0	111.4	E371 K372 F373 T378 D379	E371-K375 VanDerWaalsContact O-CB 3.25Å; E371-K375 WeakPolarHBondContact O-CB 3.46Å; E371-K375 PolarHBondContact O-N 2.87Å; K372-K375 PolarHBondContact O-N 3.32Å; F373-K375 VanDerWaalsContact C-N 3.29Å; F373-K375 PolarHBondContact O-N 2.94Å; K375-T378 PolarHBondContact O-N 2.81Å; K375-D379 WeakPolarHBondContact O-CB 3.23Å; K375-D379 PolarHBondContact O-N 3.04Å
376	E	56.4	Low	56.2	Low	111 Å²	111	109.8 Å²	109.8	52%	0.519	54%	0.535	S	S	.	.	H	α-helix	trans	-65.7	-39.5	175	-74.7	171.1	176	0	0	113	K372 F373 D379 S380	K372-E376 WeakPolarHBondContact O-CG 3.37Å; K372-E376 PolarHBondContact O-N 3.43Å; F373-E376 PolarHBondContact O-N 3.34Å; E376-D379 PolarHBondContact O-N 3.04Å; E376-S380 WeakPolarHBondContact O-CB 3.28Å; E376-S380 PolarHBondContact O-N 3.05Å
377	D	56.6	Low	56	Low	83 Å²	83	114.8 Å²	114.8	44%	0.444	55%	0.551	S	S	.	*	H	α-helix	trans	-68	-37	175.1	-85.5	-27.4	0	0	0	112.3	F373 S380 M381	F373-D377 PolarHBondContact O-N 3.43Å; D377-S380 PolarHBondContact O-N 3.35Å; D377-M381 WeakPolarHBondContact O-CB 3.35Å; D377-M381 WeakPolarHBondContact O-CG 3.38Å; D377-M381 PolarHBondContact O-N 3.47Å
378	T	58.4	Low	55.7	Low	94 Å²	94	119.6 Å²	119.6	58%	0.577	57%	0.567	S	S	*	*	H	α-helix	trans	-67.8	-41.3	176.3	-51.7	0	0	0	0	111	N374 K375 S382	N374-T378 WeakPolarHBondContact O-CB 3.31Å; N374-T378 PolarHBondContact O-N 2.84Å; N374-T378 PolarHBondContact O-OG1 3.05Å; K375-T378 PolarHBondContact O-N 2.81Å; T378-S382 VanDerWaalsContact O-CB 3.29Å; T378-S382 WeakPolarHBondContact O-CB 3.34Å; T378-S382 PolarHBondContact O-N 2.7Å
379	D	58.6	Low	55.7	Low	81 Å²	81	118.6 Å²	118.6	43%	0.433	57%	0.569	S	S	.	*	H	α-helix	trans	-69.8	-33.8	176.1	-74.5	-18.3	0	0	0	112.4	K375 E376 R383	K375-D379 WeakPolarHBondContact O-CB 3.23Å; K375-D379 PolarHBondContact O-N 3.04Å; E376-D379 PolarHBondContact O-N 3.04Å; D379-R383 WeakPolarHBondContact O-CB 3.33Å; D379-R383 PolarHBondContact O-N 3.07Å
380	S	57.1	Low	55.8	Low	48 Å²	48	118.4 Å²	118.4	34%	0.336	57%	0.57	S	S	.	*	H	α-helix	trans	-67.3	-44.2	173.9	169	0	0	0	0	112.4	E376 D377 R383 R384	E376-S380 WeakPolarHBondContact O-CB 3.28Å; E376-S380 PolarHBondContact O-N 3.05Å; D377-S380 PolarHBondContact O-N 3.35Å; S380-R383 PolarHBondContact O-N 3.41Å; S380-R384 PolarHBondContact O-N 2.75Å
381	M	56.6	Low	55.6	Low	117 Å²	117	120.1 Å²	120.1	58%	0.576	58%	0.584	S	S	*	*	H	α-helix	trans	-68.2	-40.1	175.7	-76	-133	71.8	0	0	112.3	D377 R384 Q385	D377-M381 WeakPolarHBondContact O-CB 3.35Å; D377-M381 WeakPolarHBondContact O-CG 3.38Å; D377-M381 PolarHBondContact O-N 3.47Å; M381-R384 PolarHBondContact O-N 3.02Å; M381-Q385 PolarHBondContact O-N 2.94Å
382	S	57.6	Low	55	Low	65 Å²	65	124.3 Å²	124.3	46%	0.455	59%	0.594	S	S	.	*	H	α-helix	trans	-58.9	-46.8	173.1	172.5	0	0	0	0	111.3	T378 R384 Q385 T386	T378-S382 VanDerWaalsContact O-CB 3.29Å; T378-S382 WeakPolarHBondContact O-CB 3.34Å; T378-S382 PolarHBondContact O-N 2.7Å; S382-R384 PolarHBondContact O-N 2.92Å; S382-Q385 PolarHBondContact O-N 3.49Å; S382-T386 PolarHBondContact O-N 3.38Å; S382-T386 PolarHBondContact O-OG1 3.03Å
383	R	56.9	Low	54.5	Low	167 Å²	167	122.5 Å²	122.5	63%	0.63	60%	0.599	S	S	*	*	H	α-helix	trans	-61.6	-42.4	175.5	-115.1	179	-81.4	-164.6	-6	112.6	D379 S380 T386 F387	D379-R383 WeakPolarHBondContact O-CB 3.33Å; D379-R383 PolarHBondContact O-N 3.07Å; S380-R383 PolarHBondContact O-N 3.41Å; R383-T386 WeakPolarHBondContact CA-OG1 3.35Å; R383-T386 PolarHBondContact O-N 3.49Å; R383-T386 PolarHBondContact O-OG1 3.31Å; R383-F387 WeakPolarHBondContact O-CD2 3.29Å; R383-F387 PolarHBondContact O-N 2.97Å
384	R	56.3	Low	53.9	Low	172 Å²	172	122 Å²	122	65%	0.649	61%	0.609	S	S	*	*	H	α-helix	trans	-64.8	-40.9	176.1	-80.3	-177	-179.8	169.2	2.5	112	S380 M381 S382 F387 Y388	S380-R384 PolarHBondContact O-N 2.75Å; M381-R384 PolarHBondContact O-N 3.02Å; S382-R384 PolarHBondContact O-N 2.92Å; R384-F387 PolarHBondContact O-N 2.89Å; R384-Y388 WeakPolarHBondContact O-CD2 3.36Å; R384-Y388 PolarHBondContact O-N 2.76Å
385	Q	55.8	Low	53.6	Low	139 Å²	139	124.6 Å²	124.6	65%	0.65	63%	0.628	S	S	*	*	H	α-helix	trans	-67.1	-36.8	177.2	-84.7	-177.8	-25.9	0	0	112.9	M381 S382 Y388 S389	M381-Q385 PolarHBondContact O-N 2.94Å; S382-Q385 PolarHBondContact O-N 3.49Å; Q385-Y388 PolarHBondContact O-N 3.26Å; Q385-S389 WeakPolarHBondContact O-CB 3.4Å; Q385-S389 PolarHBondContact O-N 2.96Å
386	T	57.9	Low	53	Low	80 Å²	80	124.9 Å²	124.9	49%	0.491	64%	0.637	S	S	.	*	H	α-helix	trans	-67.8	-37.5	174.5	18.9	0	0	0	0	112.3	S382 R383 S389 N390	S382-T386 PolarHBondContact O-N 3.38Å; S382-T386 PolarHBondContact O-OG1 3.03Å; R383-T386 WeakPolarHBondContact CA-OG1 3.35Å; R383-T386 PolarHBondContact O-N 3.49Å; R383-T386 PolarHBondContact O-OG1 3.31Å; T386-S389 PolarHBondContact O-N 3.35Å; T386-N390 PolarHBondContact O-N 2.86Å; T386-N390 VanDerWaalsContact O-N 3.11Å
387	F	54.9	Low	52.3	Low	152 Å²	152	124.1 Å²	124.1	67%	0.667	64%	0.644	S	S	*	*	H	α-helix	trans	-66.4	-37.2	174	-95.3	-92.1	0	0	0	113.2	R383 R384 N391	R383-F387 WeakPolarHBondContact O-CD2 3.29Å; R383-F387 PolarHBondContact O-N 2.97Å; R384-F387 PolarHBondContact O-N 2.89Å; F387-N391 PolarHBondContact O-N 3.42Å
388	Y	52.1	Low	51.6	Low	197 Å²	197	126.8 Å²	126.8	77%	0.773	66%	0.663	S	S	*	*	H	α-helix	trans	-73.8	-26.2	176.1	-90.3	-79.5	0	0	0	113.4	R384 Q385	R384-Y388 WeakPolarHBondContact O-CD2 3.36Å; R384-Y388 PolarHBondContact O-N 2.76Å; Q385-Y388 PolarHBondContact O-N 3.26Å
389	S	55.1	Low	50.8	Low	91 Å²	91	125.9 Å²	125.9	64%	0.636	67%	0.673	S	S	*	*	H	α-helix	trans	-81.4	-30	177	-164.4	0	0	0	0	113.1	Q385 T386	Q385-S389 WeakPolarHBondContact O-CB 3.4Å; Q385-S389 PolarHBondContact O-N 2.96Å; T386-S389 PolarHBondContact O-N 3.35Å
390	N	54.8	Low	49.9	Very low	133 Å²	133	130 Å²	130	71%	0.711	69%	0.692	S	S	*	*	H	α-helix	trans	-84.6	-15.6	-179.8	-93.7	2.8	0	0	0	114.7	T386 R392	T386-N390 PolarHBondContact O-N 2.86Å; T386-N390 VanDerWaalsContact O-N 3.11Å; N390-R392 VanDerWaalsContact C-N 3.34Å
391	N	50.6	Low	49.1	Very low	145 Å²	145	139 Å²	139	78%	0.775	72%	0.718	S	S	*	*	T	Hydrogen-bonded Turn	trans	-91	10.5	177.3	-97.3	5.1	0	0	0	114.3	F387	F387-N391 PolarHBondContact O-N 3.42Å
392	R	44.3	Very low	48.3	Very low	228 Å²	228	142 Å²	142	86%	0.86	73%	0.728	S	S	*	*			trans	-109.2	67.8	176.5	-150.5	174.3	-167.3	161.7	2.4	110.2	N390	N390-R392 VanDerWaalsContact C-N 3.34Å
393	S	43.6	Very low	47.5	Very low	102 Å²	102	146 Å²	146	71%	0.713	75%	0.745	S	S	*	*			trans	-69.2	146.5	170	-62.7	0	0	0	0	111.1
394	P	40.2	Very low	46.8	Very low	119 Å²	119	143.6 Å²	143.6	77%	0.773	75%	0.753	S	S	*	*			trans	-86	120.9	-167.1	32.7	-31.4	0	0	0	111.5
395	T	48.7	Very low	46.1	Very low	144 Å²	144	141 Å²	141	88%	0.883	76%	0.758	S	S	*	*			trans	-102.5	106.4	163.2	44.2	0	0	0	0	110.1
396	N	41.2	Very low	45.3	Very low	155 Å²	155	144.4 Å²	144.4	83%	0.829	77%	0.771	S	S	*	*			trans	-34	124.2	161.1	-77	-23.6	0	0	0	112.1
397	S	40.7	Very low	44.5	Very low	94 Å²	94	146.2 Å²	146.2	66%	0.657	79%	0.787	S	S	*	*				90.5	128.5	83.8	-173.4	0	0	0	0	113.7
398	T	42.7	Very low	43.8	Very low	140 Å²	140	144.6 Å²	144.6	86%	0.859	80%	0.795	S	S	*	*			trans	93.5	129.1	160.1	70.7	0	0	0	0	120.9
399	G	40.7	Very low	43.1	Very low	75 Å²	75	144.9 Å²	144.9	77%	0.773	80%	0.8	S	S	*	*			trans	101.1	70.9	158.3	0	0	0	0	0	116
400	M	40.5	Very low	42.4	Very low	168 Å²	168	145.1 Å²	145.1	83%	0.828	80%	0.802	S	S	*	*				80.5	100.4	80.8	-152.8	-179.8	86.9	0	0	115.2
401	W	39.9	Very low	41.7	Very low	237 Å²	237	145.2 Å²	145.2	90%	0.898	80%	0.801	S	S	*	*			trans	57.6	126.5	146.8	-62.7	61.8	0	0	0	118.3
402	K	39.7	Very low	41.2	Very low	178 Å²	178	147.7 Å²	147.7	77%	0.774	80%	0.804	S	S	*	*				178	131.1	66.8	-146.4	176	175.6	176.3	0	105.5
403	D	40.6	Very low	41	Very low	151 Å²	151	145.8 Å²	145.8	81%	0.807	80%	0.803	S	S	*	*				-177.1	144.4	95.4	-85.5	-35.7	0	0	0	112.1
404	S	42.6	Very low	41.1	Very low	115 Å²	115	148.8 Å²	148.8	80%	0.804	81%	0.809	S	S	*	*			trans	-62.3	-174.8	-178.3	-87.2	0	0	0	0	117.1
405	P	41.7	Very low	41.3	Very low	118 Å²	118	148.1 Å²	148.1	77%	0.766	81%	0.805	S	S	*	*			cis	-134.6	155.6	-45.6	36.2	-19.7	0	0	0	112.7
406	K	38.6	Very low	41.2	Very low	211 Å²	211	147.7 Å²	147.7	92%	0.917	80%	0.802	S	S	*	*			trans	-125.6	113.6	164.2	-86.2	-174.9	-179.6	175	0	111.9
407	S	41	Very low	41.3	Very low	118 Å²	118	145.4 Å²	145.4	83%	0.825	80%	0.798	S	S	*	*			trans	30.8	109.7	140.1	-167.4	0	0	0	0	118.1
408	S	41.1	Very low	41.8	Very low	118 Å²	118	151.4 Å²	151.4	83%	0.825	83%	0.831	S	S	*	*			trans	-71.3	123.6	172.7	-156.1	0	0	0	0	111.4
409	K	36.8	Very low	41.8	Very low	203 Å²	203	152 Å²	152	88%	0.883	83%	0.829	S	S	*	*			trans	-97.6	130.9	159.3	-79.3	180	176.5	175.8	0	107.7
410	S	40	Very low	41.8	Very low	96 Å²	96	156.1 Å²	156.1	67%	0.671	83%	0.832	S	S	*	*			trans	-146.9	101.7	161.7	-167.7	0	0	0	0	108.2
411	I	41.2	Very low	41.9	Very low	135 Å²	135	155.4 Å²	155.4	69%	0.692	83%	0.833	S	S	*	*				75.8	111.8	101.2	-66.7	166.3	0	0	0	111.7
412	K	40.4	Very low	42	Very low	196 Å²	196	150.6 Å²	150.6	85%	0.852	83%	0.829	S	S	*	*				167.8	153.3	95.3	-127.7	154.4	-163.7	-178.3	0	111.5
413	F	39	Very low	42.1	Very low	189 Å²	189	148.9 Å²	148.9	83%	0.829	83%	0.832	S	S	*	*			trans	-57.5	157.9	178.4	-78.9	-109	0	0	0	114.8
414	I	46.5	Very low	42.2	Very low	164 Å²	164	148.7 Å²	148.7	84%	0.841	83%	0.834	S	S	*	*				-175.6	135.2	122.4	-83.3	145.7	0	0	0	108.7
415	P	43.2	Very low	42.2	Very low	105 Å²	105	151.1 Å²	151.1	68%	0.682	84%	0.836	S	S	*	*			trans	-97.7	158.2	169.4	36.9	-29	0	0	0	112.1
416	V	47.1	Very low	42.3	Very low	136 Å²	136	153.7 Å²	153.7	82%	0.824	84%	0.841	S	S	*	*			trans	169.8	131.3	139.4	152.6	0	0	0	0	112.9
417	S	44.1	Very low	42.6	Very low	106 Å²	106	148.9 Å²	148.9	74%	0.741	84%	0.835	S	S	*	*			trans	45.1	124.1	147.5	-52.3	0	0	0	0	125.2
418	T	50.7	Low	42.7	Very low	221 Å²	221	151.7 Å²	151.7	100%	1.356	84%	0.836	S	S	*	*				-142.7	0	105.9	35.1	0	0	0	0	109.8

Retrieved 418 of 418 residues in 941.5 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).