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Vasoactive intestinal polypeptide receptor 2

G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP)^1,2,3. Binds VIP and both PACAP27 and PACAP38 bioactive peptides with the following order of potency PACAP38 = VIP > PACAP27^4,5. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway^6,7,8. May be coupled to phospholipase C.

AlphaFold DB , UniProt , Accession P41587, Species HUMAN (Homo sapiens, Human), Gene VIPR2, Length 438 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	43.2	Very low	43.7	Very low	225 Å²	225	114.1 Å²	114.1	100%	1.108	60%	0.599	S	S	*	*				0	-0.2	0	-148.2	171.3	172	0	0	113.3
2	R	39.1	Very low	43.4	Very low	235 Å²	235	107.8 Å²	107.8	89%	0.887	57%	0.571	S	S	*	*			trans	-103.1	141.8	144.9	-69.4	179	176.3	-178.3	-2.3	105.9
3	T	41.4	Very low	43	Very low	133 Å²	133	117.9 Å²	117.9	82%	0.816	60%	0.597	S	S	*	*	S	Bend	trans	83.4	127.9	-176.4	75.9	0	0	0	0	116.7
4	L	46.3	Very low	42.6	Very low	126 Å²	126	119.9 Å²	119.9	66%	0.66	61%	0.609	S	S	*	*			trans	83.5	49.1	172.8	-59	150.9	0	0	0	116.8	L245	L4-L245 HydrophobicContact CD2-CD2 3.87Å
5	L	46.1	Very low	42.3	Very low	112 Å²	112	120.3 Å²	120.3	59%	0.586	61%	0.612	S	S	*	*			trans	-70.7	124.7	139.5	-137.3	93.3	0	0	0	105.6	L9 L10	L5-L9 HydrophobicContact CD2-CB 3.57Å; L5-L9 HydrophobicContact CD2-CD1 4.32Å; L5-L9 HydrophobicContact CG-CB 4.2Å; L5-L9 HydrophobicContact CG-CD1 4.18Å; L5-L10 HydrophobicContact CD2-CD1 4.35Å; L5-L10 HydrophobicContact CD2-CG 4.37Å
6	P	43.4	Very low	42	Very low	27 Å²	27	117 Å²	117	18%	0.175	61%	0.609	C	S	.	*			trans	-57.3	137.1	174.3	21.8	-30.2	0	0	0	108.5	A8 L9 L167	P6-A8 PolarHBondContact O-N 3.44Å; P6-L9 HydrophobicContact CG-CD1 3.99Å; P6-L9 HydrophobicContact CG-CG 4.47Å; P6-L9 PolarHBondContact O-N 2.92Å; P6-L167 HydrophobicContact CG-CD2 3.91Å
7	P	42.8	Very low	42	Very low	110 Å²	110	117.4 Å²	117.4	71%	0.714	62%	0.62	S	S	*	*	H	α-helix	trans	-54.3	-21.8	-179.2	17.6	-29	0	0	0	113	L9 L10 T11	P7-L9 VanDerWaalsContact C-N 3.28Å; P7-L9 PolarHBondContact O-N 3.05Å; P7-L10 PolarHBondContact O-N 3.09Å; P7-T11 PolarHBondContact O-N 3.29Å
8	A	46.1	Very low	42.1	Very low	20 Å²	20	114.6 Å²	114.6	17%	0.165	61%	0.608	C	S	.	*	H	α-helix	trans	-62.8	-22.1	174.2	0	0	0	0	0	115.4	P6 T11	P6-A8 PolarHBondContact O-N 3.44Å; A8-T11 PolarHBondContact O-OG1 3.03Å; A8-T11 VanDerWaalsContact O-OG1 3.08Å
9	L	46.8	Very low	42.2	Very low	51 Å²	51	113.5 Å²	113.5	27%	0.267	60%	0.603	S	S	.	*	H	α-helix	trans	-86.6	-22.6	177.5	-88.8	165.7	0	0	0	113.2	L5 P6 P7 L167	L5-L9 HydrophobicContact CD2-CB 3.57Å; L5-L9 HydrophobicContact CD2-CD1 4.32Å; L5-L9 HydrophobicContact CG-CB 4.2Å; L5-L9 HydrophobicContact CG-CD1 4.18Å; P6-L9 HydrophobicContact CG-CD1 3.99Å; P6-L9 HydrophobicContact CG-CG 4.47Å; P6-L9 PolarHBondContact O-N 2.92Å; P7-L9 VanDerWaalsContact C-N 3.28Å; P7-L9 PolarHBondContact O-N 3.05Å; L9-L167 HydrophobicContact CD1-CD1 4.08Å; L9-L167 HydrophobicContact CD1-CD2 3.83Å; L9-L167 HydrophobicContact CD2-CD1 4.41Å; L9-L167 HydrophobicContact CG-CD1 4.49Å
10	L	42.3	Very low	42.4	Very low	124 Å²	124	109.8 Å²	109.8	65%	0.649	59%	0.586	S	S	*	*	H	α-helix	trans	-81.1	-21.7	175.5	-89.1	142.7	0	0	0	112.4	L5 P7	L5-L10 HydrophobicContact CD2-CD1 4.35Å; L5-L10 HydrophobicContact CD2-CG 4.37Å; P7-L10 PolarHBondContact O-N 3.09Å
11	T	43.1	Very low	42.8	Very low	92 Å²	92	105.5 Å²	105.5	56%	0.564	56%	0.563	S	S	*	*	S	Bend	trans	-83.3	-18.3	173.8	48.4	0	0	0	0	113.2	P7 A8 W13	P7-T11 PolarHBondContact O-N 3.29Å; A8-T11 PolarHBondContact O-OG1 3.03Å; A8-T11 VanDerWaalsContact O-OG1 3.08Å; T11-W13 PolarHBondContact O-N 3.21Å
12	C	40.3	Very low	43.3	Very low	39 Å²	39	97 Å²	97	26%	0.264	52%	0.521	S	S	.	.	G	3₁₀ helix	trans	-79.3	-13.3	-175.4	-149.6	0	0	0	0	114.1	L14	C12-L14 VanDerWaalsContact C-N 3.34Å
13	W	38.5	Very low	44	Very low	239 Å²	239	88.9 Å²	88.9	91%	0.905	50%	0.498	S	S	*	.	G	3₁₀ helix	trans	-88.7	3.9	175.7	-82.5	83.8	0	0	0	114.2	T11	T11-W13 PolarHBondContact O-N 3.21Å
14	L	36.6	Very low	44.8	Very low	146 Å²	146	87.5 Å²	87.5	76%	0.764	48%	0.483	S	S	*	.	G	3₁₀ helix	trans	-114.6	25.3	179.2	-81.6	155.9	0	0	0	112.4	C12 A16	C12-L14 VanDerWaalsContact C-N 3.34Å; L14-A16 PolarHBondContact O-N 3.14Å
15	L	38.4	Very low	45.6	Very low	126 Å²	126	82.1 Å²	82.1	66%	0.66	46%	0.455	S	S	*	.			trans	-68.6	82.7	175.4	-67.2	173.1	0	0	0	109.9
16	A	38.1	Very low	46.5	Very low	67 Å²	67	81.4 Å²	81.4	55%	0.554	45%	0.445	S	S	*	.			trans	-53.2	149.5	156.2	0	0	0	0	0	108.8	L14 V18	L14-A16 PolarHBondContact O-N 3.14Å; A16-V18 PolarHBondContact O-N 2.83Å
17	P	42.1	Very low	47.6	Very low	123 Å²	123	84 Å²	84	80%	0.799	45%	0.453	S	S	*	.			trans	-57.3	110.5	175.5	24	-32.2	0	0	0	108.6	N19	P17-N19 PolarHBondContact O-N 3.03Å
18	V	43.5	Very low	48.9	Very low	68 Å²	68	82.6 Å²	82.6	41%	0.412	44%	0.437	S	S	.	.			trans	-78.6	107.6	177.6	-178.7	0	0	0	0	106.8	A16 S20	A16-V18 PolarHBondContact O-N 2.83Å; V18-S20 PolarHBondContact O-N 2.68Å
19	N	44.3	Very low	50.2	Low	94 Å²	94	83.6 Å²	83.6	50%	0.503	44%	0.439	S	S	.	.			trans	-59	126.6	171	-81.9	-7.6	0	0	0	109	P17	P17-N19 PolarHBondContact O-N 3.03Å
20	S	46.6	Very low	51.6	Low	39 Å²	39	83 Å²	83	27%	0.273	44%	0.436	S	S	.	.			trans	-122.7	147.9	-167.3	43.4	0	0	0	0	111.6	V18	V18-S20 PolarHBondContact O-N 2.68Å
21	I	49.2	Very low	53.4	Low	19 Å²	19	78.6 Å²	78.6	10%	0.097	41%	0.412	C	S	.	.			trans	-102.6	119.3	-178.4	-60.5	170.5	0	0	0	106.9	C25 S198 W199	I21-C25 HydrophobicContact CG2-CB 3.63Å; I21-S198 WeakPolarHBondContact CD1-OG 3.44Å; I21-S198 WeakPolarHBondContact CG1-OG 3.22Å; I21-W199 HydrophobicContact CD1-CB 4.26Å; I21-W199 VanDerWaalsContact CD1-CD1 3.44Å; I21-W199 HydrophobicContact CD1-CD2 3.66Å; I21-W199 HydrophobicContact CD1-CG 3.54Å; I21-W199 HydrophobicContact CD1-CZ2 4.32Å
22	H	54.9	Low	55.2	Low	48 Å²	48	78 Å²	78	22%	0.222	40%	0.403	C	S	.	.			trans	-67.7	144.9	172	-165	-101.1	0	0	0	109.3	E24 C25 L183	H22-E24 VanDerWaalsContact CE1-CD 3.47Å; H22-E24 IonicContact CE1-OE1 2.95Å; H22-E24 IonicContact CE1-OE2 3.8Å; H22-E24 VanDerWaalsContact ND1-CB 3.27Å; H22-E24 WeakPolarHBondContact ND1-CB 3.47Å; H22-E24 VanDerWaalsContact ND1-CG 3.3Å; H22-E24 WeakPolarHBondContact ND1-CG 3.44Å; H22-E24 PolarHBondContact ND1-N 2.91Å; H22-E24 IonicContact ND1-OE2 3.78Å; H22-E24 PolarHBondContact O-N 2.88Å; H22-E24 VanDerWaalsContact O-N 3.13Å; H22-C25 WeakPolarHBondContact O-CA 3.08Å; H22-C25 VanDerWaalsContact O-CB 3.25Å; H22-C25 WeakPolarHBondContact O-CB 3.46Å; H22-C25 PolarHBondContact O-N 3.22Å; H22-L183 PolarHBondContact CD2-O 2.99Å; H22-L183 PolarHBondContact NE2-O 3.36Å
23	P	53.2	Low	57.3	Low	64 Å²	64	81 Å²	81	42%	0.416	41%	0.413	S	S	.	.	H	α-helix	trans	-55.9	-28.4	174.7	19.5	-30.1	0	0	0	112.9	C25 R26 L183	P23-C25 VanDerWaalsContact C-N 3.25Å; P23-C25 PolarHBondContact O-N 3.22Å; P23-R26 WeakPolarHBondContact O-CB 3.47Å; P23-R26 PolarHBondContact O-N 3.28Å; P23-R26 VanDerWaalsContact O-N 3.17Å; P23-L183 WeakPolarHBondContact CD-O 3.4Å
24	E	59	Low	59.5	Low	104 Å²	104	73.1 Å²	73.1	49%	0.486	39%	0.386	S	S	.	.	H	α-helix	trans	-66.1	-24.8	171.3	-65	176.9	177	0	0	113.3	H22 R26 F27 H28	H22-E24 VanDerWaalsContact CE1-CD 3.47Å; H22-E24 IonicContact CE1-OE1 2.95Å; H22-E24 IonicContact CE1-OE2 3.8Å; H22-E24 VanDerWaalsContact ND1-CB 3.27Å; H22-E24 WeakPolarHBondContact ND1-CB 3.47Å; H22-E24 VanDerWaalsContact ND1-CG 3.3Å; H22-E24 WeakPolarHBondContact ND1-CG 3.44Å; H22-E24 PolarHBondContact ND1-N 2.91Å; H22-E24 IonicContact ND1-OE2 3.78Å; H22-E24 PolarHBondContact O-N 2.88Å; H22-E24 VanDerWaalsContact O-N 3.13Å; E24-R26 PolarHBondContact O-N 2.93Å; E24-F27 WeakPolarHBondContact O-CB 3.34Å; E24-F27 PolarHBondContact O-N 2.87Å; E24-F27 VanDerWaalsContact O-N 3.1Å; E24-H28 PolarHBondContact O-CD2 2.84Å; E24-H28 VanDerWaalsContact O-CD2 3.27Å; E24-H28 PolarHBondContact O-N 3.41Å; E24-H28 VanDerWaalsContact O-N 3.09Å
25	C	62.6	Low	62	Low	12 Å²	12	70.7 Å²	70.7	8%	0.081	37%	0.371	C	S	.	.	H	α-helix	trans	-65.5	-26.3	173.9	-77.6	0	0	0	0	112.3	I21 H22 P23 F27 H28 L29 C192	I21-C25 HydrophobicContact CG2-CB 3.63Å; H22-C25 WeakPolarHBondContact O-CA 3.08Å; H22-C25 VanDerWaalsContact O-CB 3.25Å; H22-C25 WeakPolarHBondContact O-CB 3.46Å; H22-C25 PolarHBondContact O-N 3.22Å; P23-C25 VanDerWaalsContact C-N 3.25Å; P23-C25 PolarHBondContact O-N 3.22Å; C25-F27 VanDerWaalsContact C-N 3.31Å; C25-F27 PolarHBondContact O-N 3.46Å; C25-H28 PolarHBondContact O-N 3.44Å; C25-L29 VanDerWaalsContact O-CB 3.27Å; C25-L29 WeakPolarHBondContact O-CB 3.22Å; C25-L29 VanDerWaalsContact O-CD1 3.29Å; C25-L29 WeakPolarHBondContact O-CD1 3.32Å; C25-L29 WeakPolarHBondContact O-CG 3.5Å; C25-L29 PolarHBondContact O-N 3.28Å; C25-C192 WeakPolarHBondContact CA-SG 3.43Å; C25-C192 HydrophobicContact CB-CB 3.87Å; C25-C192 WeakPolarHBondContact CB-SG 3.48Å; C25-C192 WeakPolarHBondContact SG-CA 3.28Å; C25-C192 WeakPolarHBondContact SG-CB 3.3Å; C25-C192 CovalentContact SG-SG 2.06Å; C25-C192 PolarHBondContact SG-SG 3.44Å
26	R	64.4	Low	64.3	Low	98 Å²	98	68.1 Å²	68.1	37%	0.37	36%	0.361	S	S	.	.	H	α-helix	trans	-61.3	-44	171.4	-177.5	-179.3	178.1	157.9	3.6	111	P23 E24 L29 E30 T274	P23-R26 WeakPolarHBondContact O-CB 3.47Å; P23-R26 PolarHBondContact O-N 3.28Å; P23-R26 VanDerWaalsContact O-N 3.17Å; E24-R26 PolarHBondContact O-N 2.93Å; R26-L29 PolarHBondContact O-N 3.02Å; R26-E30 IonicContact CZ-OE1 3.39Å; R26-E30 IonicContact NE-OE1 2.97Å; R26-E30 PolarHBondContact NE-OE1 2.94Å; R26-E30 IonicContact NH2-OE1 2.9Å; R26-E30 WeakPolarHBondContact O-CG 3.35Å; R26-E30 PolarHBondContact O-N 2.64Å; R26-T274 VanDerWaalsContact NH1-CG2 3.26Å; R26-T274 PolarHBondContact NH1-OG1 3.38Å
27	F	67.4	Low	66.8	Low	80 Å²	80	69 Å²	69	35%	0.351	35%	0.352	S	S	.	.	H	α-helix	trans	-61.7	-46.2	177.4	-177.3	-89.1	0	0	0	111.1	E24 C25 L29 E30 I31 V78 F82	E24-F27 WeakPolarHBondContact O-CB 3.34Å; E24-F27 PolarHBondContact O-N 2.87Å; E24-F27 VanDerWaalsContact O-N 3.1Å; C25-F27 VanDerWaalsContact C-N 3.31Å; C25-F27 PolarHBondContact O-N 3.46Å; F27-L29 PolarHBondContact O-N 3.49Å; F27-E30 PolarHBondContact O-N 3.09Å; F27-I31 HydrophobicContact CD1-CD1 3.64Å; F27-I31 HydrophobicContact CE1-CD1 3.21Å; F27-I31 HydrophobicContact CE1-CG1 4.38Å; F27-I31 HydrophobicContact CZ-CD1 3.8Å; F27-I31 WeakPolarHBondContact O-CG1 3.22Å; F27-I31 PolarHBondContact O-N 2.89Å; F27-I31 VanDerWaalsContact O-N 3.07Å; F27-V78 HydrophobicContact CD2-CG1 3.15Å; F27-V78 HydrophobicContact CE2-CB 4.41Å; F27-V78 HydrophobicContact CE2-CG1 3.06Å; F27-V78 HydrophobicContact CG-CG1 4.11Å; F27-V78 HydrophobicContact CZ-CG1 3.93Å; F27-F82 HydrophobicContact CD2-CE2 4.31Å
28	H	70.4	Confident	69	Low	81 Å²	81	63.4 Å²	63.4	38%	0.375	32%	0.315	S	S	.	.	H	α-helix	trans	-62.2	-42	175.5	-77.2	-73.8	0	0	0	113.1	E24 C25 I31 Q32	E24-H28 PolarHBondContact O-CD2 2.84Å; E24-H28 VanDerWaalsContact O-CD2 3.27Å; E24-H28 PolarHBondContact O-N 3.41Å; E24-H28 VanDerWaalsContact O-N 3.09Å; C25-H28 PolarHBondContact O-N 3.44Å; H28-I31 PolarHBondContact O-N 2.86Å; H28-Q32 WeakPolarHBondContact O-CB 3.34Å; H28-Q32 PolarHBondContact O-N 3.16Å
29	L	72.1	Confident	71.2	Confident	41 Å²	41	62 Å²	62	22%	0.215	31%	0.312	C	S	.	.	H	α-helix	trans	-65.4	-42.2	178.2	-74.7	162.8	0	0	0	112.1	C25 R26 F27 I31 Q32 E33 D194 W199	C25-L29 VanDerWaalsContact O-CB 3.27Å; C25-L29 WeakPolarHBondContact O-CB 3.22Å; C25-L29 VanDerWaalsContact O-CD1 3.29Å; C25-L29 WeakPolarHBondContact O-CD1 3.32Å; C25-L29 WeakPolarHBondContact O-CG 3.5Å; C25-L29 PolarHBondContact O-N 3.28Å; R26-L29 PolarHBondContact O-N 3.02Å; F27-L29 PolarHBondContact O-N 3.49Å; L29-I31 VanDerWaalsContact C-N 3.32Å; L29-I31 PolarHBondContact O-N 3.32Å; L29-Q32 PolarHBondContact O-N 2.87Å; L29-E33 WeakPolarHBondContact O-CB 3.43Å; L29-E33 PolarHBondContact O-N 3.33Å; L29-D194 VanDerWaalsContact CD2-OD1 3.29Å; L29-D194 WeakPolarHBondContact CD2-OD1 3.31Å; L29-W199 HydrophobicContact CD1-CH2 3.94Å; L29-W199 HydrophobicContact CD1-CZ2 3.45Å; L29-W199 VanDerWaalsContact CD1-CZ2 3.45Å
30	E	76.8	Confident	73.4	Confident	40 Å²	40	64 Å²	64	19%	0.187	32%	0.318	C	S	.	.	H	α-helix	trans	-62.4	-40.6	175.4	-75.5	177.6	-165.3	0	0	110.9	R26 F27 E33 E34 V78 N81	R26-E30 IonicContact CZ-OE1 3.39Å; R26-E30 IonicContact NE-OE1 2.97Å; R26-E30 PolarHBondContact NE-OE1 2.94Å; R26-E30 IonicContact NH2-OE1 2.9Å; R26-E30 WeakPolarHBondContact O-CG 3.35Å; R26-E30 PolarHBondContact O-N 2.64Å; F27-E30 PolarHBondContact O-N 3.09Å; E30-E33 PolarHBondContact O-N 3.32Å; E30-E34 WeakPolarHBondContact O-CG 3.22Å; E30-E34 PolarHBondContact O-N 3.32Å; E30-V78 HydrophobicContact CB-CG2 4.09Å; E30-N81 PolarHBondContact OE2-ND2 3.45Å
31	I	80.1	Confident	75.4	Confident	31 Å²	31	65 Å²	65	16%	0.159	32%	0.319	C	S	.	.	H	α-helix	trans	-63.9	-44.4	174.4	-70.7	175.9	0	0	0	111.5	F27 H28 L29 E33 E34 E35 W56 N58 V78	F27-I31 HydrophobicContact CD1-CD1 3.64Å; F27-I31 HydrophobicContact CE1-CD1 3.21Å; F27-I31 HydrophobicContact CE1-CG1 4.38Å; F27-I31 HydrophobicContact CZ-CD1 3.8Å; F27-I31 WeakPolarHBondContact O-CG1 3.22Å; F27-I31 PolarHBondContact O-N 2.89Å; F27-I31 VanDerWaalsContact O-N 3.07Å; H28-I31 PolarHBondContact O-N 2.86Å; L29-I31 VanDerWaalsContact C-N 3.32Å; L29-I31 PolarHBondContact O-N 3.32Å; I31-E33 VanDerWaalsContact C-N 3.32Å; I31-E33 PolarHBondContact O-N 2.99Å; I31-E34 PolarHBondContact O-N 3.14Å; I31-E35 WeakPolarHBondContact O-CB 3.44Å; I31-E35 PolarHBondContact O-N 3.48Å; I31-W56 HydrophobicContact CG2-CZ2 4.04Å; I31-N58 WeakPolarHBondContact CG2-O 3.41Å; I31-V78 HydrophobicContact CG1-CG2 4.41Å
32	Q	81.8	Confident	77.2	Confident	78 Å²	78	66.4 Å²	66.4	36%	0.364	33%	0.327	S	S	.	.	H	α-helix	trans	-65.5	-35.6	178.9	-173	176.2	-21.7	0	0	111.8	H28 L29 E35 T36 D194	H28-Q32 WeakPolarHBondContact O-CB 3.34Å; H28-Q32 PolarHBondContact O-N 3.16Å; L29-Q32 PolarHBondContact O-N 2.87Å; Q32-E35 PolarHBondContact O-N 3.46Å; Q32-T36 WeakPolarHBondContact O-CG2 3.3Å; Q32-T36 PolarHBondContact O-N 2.99Å; Q32-T36 PolarHBondContact O-OG1 3.12Å; Q32-T36 VanDerWaalsContact O-OG1 3.05Å; Q32-D194 PolarHBondContact NE2-OD2 3.42Å
33	E	83.5	Confident	78.6	Confident	102 Å²	102	74.2 Å²	74.2	48%	0.477	36%	0.355	S	S	.	.	H	α-helix	trans	-64.4	-42.1	172.9	-164.7	-170	151.9	0	0	111.4	L29 E30 I31 T36 K37	L29-E33 WeakPolarHBondContact O-CB 3.43Å; L29-E33 PolarHBondContact O-N 3.33Å; E30-E33 PolarHBondContact O-N 3.32Å; I31-E33 VanDerWaalsContact C-N 3.32Å; I31-E33 PolarHBondContact O-N 2.99Å; E33-T36 WeakPolarHBondContact CA-OG1 3.39Å; E33-T36 PolarHBondContact O-N 2.94Å; E33-T36 PolarHBondContact O-OG1 3.08Å; E33-K37 VanDerWaalsContact O-CG 3.3Å; E33-K37 WeakPolarHBondContact O-CG 3.49Å; E33-K37 PolarHBondContact O-N 3.29Å; E33-K37 WeakPolarHBondContact OE1-CE 3.45Å; E33-K37 IonicContact OE1-NZ 3.72Å; E33-K37 PolarHBondContact OE1-NZ 3.34Å
34	E	85.2	Confident	80	Confident	75 Å²	75	75.1 Å²	75.1	35%	0.35	36%	0.363	S	S	.	.	H	α-helix	trans	-70.8	-33.9	176	-66.2	-59.9	120.4	0	0	112.5	E30 I31 K37 C38 W56	E30-E34 WeakPolarHBondContact O-CG 3.22Å; E30-E34 PolarHBondContact O-N 3.32Å; I31-E34 PolarHBondContact O-N 3.14Å; E34-K37 WeakPolarHBondContact OE1-CD 3.48Å; E34-K37 IonicContact OE1-NZ 2.95Å; E34-K37 PolarHBondContact OE1-NZ 3.48Å; E34-C38 WeakPolarHBondContact O-CB 3.49Å; E34-C38 PolarHBondContact O-N 3.35Å; E34-W56 HydrophobicContact CB-CH2 3.71Å; E34-W56 HydrophobicContact CB-CZ3 4.22Å
35	E	88	Confident	80.8	Confident	94 Å²	94	73.1 Å²	73.1	44%	0.439	35%	0.353	S	S	.	.	H	α-helix	trans	-62.2	-46.5	172.5	-178.5	177	178.6	0	0	111.1	I31 Q32 C38 A39 W56	I31-E35 WeakPolarHBondContact O-CB 3.44Å; I31-E35 PolarHBondContact O-N 3.48Å; Q32-E35 PolarHBondContact O-N 3.46Å; E35-C38 WeakPolarHBondContact O-CB 3.21Å; E35-C38 PolarHBondContact O-N 3.29Å; E35-C38 VanDerWaalsContact O-N 3.16Å; E35-A39 PolarHBondContact O-N 3.37Å; E35-W56 HydrophobicContact CB-CD2 4.23Å; E35-W56 HydrophobicContact CB-CH2 4.41Å; E35-W56 HydrophobicContact CB-CZ2 3.74Å; E35-W56 HydrophobicContact CG-CD2 4.28Å; E35-W56 HydrophobicContact CG-CG 4.21Å
36	T	88	Confident	80.8	Confident	72 Å²	72	78.9 Å²	78.9	44%	0.442	39%	0.388	S	S	.	.	H	α-helix	trans	-64.4	-44.1	178.6	49.5	0	0	0	0	111.8	Q32 E33 C38 A39 E40	Q32-T36 WeakPolarHBondContact O-CG2 3.3Å; Q32-T36 PolarHBondContact O-N 2.99Å; Q32-T36 PolarHBondContact O-OG1 3.12Å; Q32-T36 VanDerWaalsContact O-OG1 3.05Å; E33-T36 WeakPolarHBondContact CA-OG1 3.39Å; E33-T36 PolarHBondContact O-N 2.94Å; E33-T36 PolarHBondContact O-OG1 3.08Å; T36-C38 VanDerWaalsContact C-N 3.27Å; T36-C38 PolarHBondContact O-N 3.49Å; T36-A39 PolarHBondContact O-N 2.95Å; T36-E40 WeakPolarHBondContact O-CG 3.46Å; T36-E40 PolarHBondContact O-N 3.37Å
37	K	88.9	Confident	80.8	Confident	87 Å²	87	80.4 Å²	80.4	38%	0.378	40%	0.4	S	S	.	.	H	α-helix	trans	-58.3	-40.2	171.3	-72.6	170.6	-169.7	160.1	0	111.9	E33 E34 E40 L41	E33-K37 VanDerWaalsContact O-CG 3.3Å; E33-K37 WeakPolarHBondContact O-CG 3.49Å; E33-K37 PolarHBondContact O-N 3.29Å; E33-K37 WeakPolarHBondContact OE1-CE 3.45Å; E33-K37 IonicContact OE1-NZ 3.72Å; E33-K37 PolarHBondContact OE1-NZ 3.34Å; E34-K37 WeakPolarHBondContact OE1-CD 3.48Å; E34-K37 IonicContact OE1-NZ 2.95Å; E34-K37 PolarHBondContact OE1-NZ 3.48Å; K37-E40 PolarHBondContact O-N 3.03Å; K37-L41 WeakPolarHBondContact O-CB 3.24Å; K37-L41 PolarHBondContact O-N 2.71Å
38	C	89.6	Confident	80.5	Confident	4 Å²	4	85.7 Å²	85.7	3%	0.027	42%	0.422	C	S	.	.	H	α-helix	trans	-64.1	-46	176.3	-171.9	0	0	0	0	111.5	E34 E35 T36 E40 L41 L42 W56 C61	E34-C38 WeakPolarHBondContact O-CB 3.49Å; E34-C38 PolarHBondContact O-N 3.35Å; E35-C38 WeakPolarHBondContact O-CB 3.21Å; E35-C38 PolarHBondContact O-N 3.29Å; E35-C38 VanDerWaalsContact O-N 3.16Å; T36-C38 VanDerWaalsContact C-N 3.27Å; T36-C38 PolarHBondContact O-N 3.49Å; C38-E40 VanDerWaalsContact C-N 3.31Å; C38-E40 PolarHBondContact O-N 3.27Å; C38-L41 WeakPolarHBondContact O-CB 3.47Å; C38-L41 PolarHBondContact O-N 2.93Å; C38-L42 WeakPolarHBondContact O-CB 3.19Å; C38-L42 VanDerWaalsContact O-CG 3.28Å; C38-L42 WeakPolarHBondContact O-CG 3.38Å; C38-L42 PolarHBondContact O-N 2.87Å; C38-W56 HydrophobicContact CB-CD2 4.42Å; C38-W56 HydrophobicContact CB-CE3 3.67Å; C38-W56 HydrophobicContact CB-CZ3 4.16Å; C38-C61 WeakPolarHBondContact CA-SG 3.23Å; C38-C61 HydrophobicContact CB-CB 3.51Å; C38-C61 WeakPolarHBondContact CB-SG 3.3Å; C38-C61 VanDerWaalsContact SG-CA 3.53Å; C38-C61 WeakPolarHBondContact SG-CB 3.27Å; C38-C61 CovalentContact SG-SG 2.03Å; C38-C61 PolarHBondContact SG-SG 3.33Å
39	A	90.1	Very high	80.5	Confident	40 Å²	40	90.3 Å²	90.3	33%	0.331	44%	0.444	S	S	.	.	H	α-helix	trans	-60.8	-39.6	178.6	0	0	0	0	0	112.1	E35 T36 R43	E35-A39 PolarHBondContact O-N 3.37Å; T36-A39 PolarHBondContact O-N 2.95Å; A39-R43 WeakPolarHBondContact O-CB 3.41Å; A39-R43 VanDerWaalsContact O-CG 3.27Å; A39-R43 WeakPolarHBondContact O-CG 3.34Å; A39-R43 PolarHBondContact O-N 3.32Å
40	E	90.2	Very high	80.8	Confident	135 Å²	135	90.9 Å²	90.9	63%	0.631	44%	0.444	S	S	*	.	H	α-helix	trans	-65.5	-46.4	173.3	-71.5	-177.7	172.7	0	0	112.1	T36 K37 C38 L42 R43 S44	T36-E40 WeakPolarHBondContact O-CG 3.46Å; T36-E40 PolarHBondContact O-N 3.37Å; K37-E40 PolarHBondContact O-N 3.03Å; C38-E40 VanDerWaalsContact C-N 3.31Å; C38-E40 PolarHBondContact O-N 3.27Å; E40-L42 VanDerWaalsContact C-N 3.34Å; E40-L42 PolarHBondContact O-N 2.79Å; E40-R43 PolarHBondContact O-N 3.32Å; E40-S44 PolarHBondContact O-N 3.39Å
41	L	88	Confident	81.1	Confident	59 Å²	59	91.9 Å²	91.9	31%	0.309	46%	0.459	S	S	.	.	H	α-helix	trans	-57.6	-47.7	177	-174.8	73.3	0	0	0	110.9	K37 C38 R43 S44 Q45 R63	K37-L41 WeakPolarHBondContact O-CB 3.24Å; K37-L41 PolarHBondContact O-N 2.71Å; C38-L41 WeakPolarHBondContact O-CB 3.47Å; C38-L41 PolarHBondContact O-N 2.93Å; L41-R43 PolarHBondContact O-N 2.86Å; L41-S44 PolarHBondContact O-N 3.04Å; L41-S44 PolarHBondContact O-OG 2.98Å; L41-Q45 PolarHBondContact O-N 3.16Å; L41-R63 HydrophobicContact CD2-CG 4.19Å
42	L	87	Confident	81.5	Confident	50 Å²	50	90.5 Å²	90.5	26%	0.262	45%	0.453	S	S	.	.	H	α-helix	trans	-67.4	-32.8	-179.9	-67.7	179.8	0	0	0	112.7	C38 E40	C38-L42 WeakPolarHBondContact O-CB 3.19Å; C38-L42 VanDerWaalsContact O-CG 3.28Å; C38-L42 WeakPolarHBondContact O-CG 3.38Å; C38-L42 PolarHBondContact O-N 2.87Å; E40-L42 VanDerWaalsContact C-N 3.34Å; E40-L42 PolarHBondContact O-N 2.79Å
43	R	85.1	Confident	81.8	Confident	212 Å²	212	91.2 Å²	91.2	80%	0.8	47%	0.466	S	S	*	.	H	α-helix	trans	-70.2	-34.7	173.2	-78.7	175.6	-178.4	161.7	3.2	113.1	A39 E40 L41 Q45	A39-R43 WeakPolarHBondContact O-CB 3.41Å; A39-R43 VanDerWaalsContact O-CG 3.27Å; A39-R43 WeakPolarHBondContact O-CG 3.34Å; A39-R43 PolarHBondContact O-N 3.32Å; E40-R43 PolarHBondContact O-N 3.32Å; L41-R43 PolarHBondContact O-N 2.86Å; R43-Q45 PolarHBondContact O-N 3.46Å
44	S	82.8	Confident	81.9	Confident	83 Å²	83	87.4 Å²	87.4	58%	0.58	45%	0.454	S	S	*	.	H	α-helix	trans	-72	-17.7	-179.2	75	0	0	0	0	113.6	E40 L41 T46	E40-S44 PolarHBondContact O-N 3.39Å; L41-S44 PolarHBondContact O-N 3.04Å; L41-S44 PolarHBondContact O-OG 2.98Å; S44-T46 PolarHBondContact O-N 2.78Å
45	Q	74.6	Confident	82.2	Confident	62 Å²	62	86.6 Å²	86.6	29%	0.29	46%	0.455	S	S	.	.			trans	-79.3	116.3	-177.9	-71.8	-161	11.9	0	0	112.3	L41 R43 E47	L41-Q45 PolarHBondContact O-N 3.16Å; R43-Q45 PolarHBondContact O-N 3.46Å; Q45-E47 VanDerWaalsContact C-N 3.33Å
46	T	62.2	Low	82.2	Confident	133 Å²	133	84.1 Å²	84.1	82%	0.816	44%	0.441	S	S	*	.			trans	-79.6	-13	-179.3	-32.2	0	0	0	0	113.3	S44 K48	S44-T46 PolarHBondContact O-N 2.78Å; T46-K48 PolarHBondContact O-N 3.44Å
47	E	65	Low	82	Confident	130 Å²	130	82.7 Å²	82.7	61%	0.607	43%	0.431	S	S	*	.			trans	-81.6	84.3	-175	-65.5	-163	171.6	0	0	112.4	Q45 H49 K50	Q45-E47 VanDerWaalsContact C-N 3.33Å; E47-H49 PolarHBondContact O-N 3.06Å; E47-H49 VanDerWaalsContact O-N 3.17Å; E47-K50 WeakPolarHBondContact OE2-CE 3.39Å; E47-K50 IonicContact OE2-NZ 3.62Å
48	K	61.7	Low	81.7	Confident	190 Å²	190	84.5 Å²	84.5	83%	0.826	44%	0.444	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.5	-0.1	-179.1	-71.4	-174.6	176.8	-178.5	0	116.2	T46	T46-K48 PolarHBondContact O-N 3.44Å
49	H	69.6	Low	81.4	Confident	178 Å²	178	87.5 Å²	87.5	82%	0.824	46%	0.46	S	S	*	.	T	Hydrogen-bonded Turn	trans	-125.9	29.8	-164.1	-62.9	92.3	0	0	0	115.2	E47	E47-H49 PolarHBondContact O-N 3.06Å; E47-H49 VanDerWaalsContact O-N 3.17Å
50	K	78.7	Confident	81.3	Confident	53 Å²	53	86.1 Å²	86.1	23%	0.23	45%	0.447	C	S	.	.			trans	-87	148.5	172.4	-64.6	-153.4	-169.3	-179.2	0	111.9	E47 P64	E47-K50 WeakPolarHBondContact OE2-CE 3.39Å; E47-K50 IonicContact OE2-NZ 3.62Å; K50-P64 HydrophobicContact CB-CB 4.07Å; K50-P64 VanDerWaalsContact CD-C 3.5Å; K50-P64 HydrophobicContact CD-CB 3.88Å; K50-P64 WeakPolarHBondContact CD-O 3.3Å; K50-P64 HydrophobicContact CG-CB 4.29Å; K50-P64 PolarHBondContact NZ-O 3.42Å
51	A	82.7	Confident	81.3	Confident	61 Å²	61	81 Å²	81	50%	0.504	43%	0.426	S	S	.	.	S	Bend	trans	-63.9	-43.4	-175.9	0	0	0	0	0	112.8	A65 V67	A51-A65 PolarHBondContact N-O 2.87Å; A51-V67 HydrophobicContact CB-CB 4.47Å; A51-V67 HydrophobicContact CB-CG2 3.35Å
52	C	88.4	Confident	81.5	Confident	3 Å²	3	78.2 Å²	78.2	2%	0.02	41%	0.411	C	S	.	.	B	Isolated β-bridge	trans	-102.2	118.7	170.9	-59.5	0	0	0	0	109.7	P64 A65 C93 W98	C52-P64 VanDerWaalsContact O-CA 3.25Å; C52-P64 WeakPolarHBondContact O-CA 3.49Å; C52-A65 PolarHBondContact N-O 3.08Å; C52-A65 PolarHBondContact O-N 2.86Å; C52-C93 HydrophobicContact CB-CB 3.79Å; C52-C93 WeakPolarHBondContact CB-SG 3.49Å; C52-C93 PolarHBondContact N-SG 3.01Å; C52-C93 WeakPolarHBondContact SG-CA 3.19Å; C52-C93 WeakPolarHBondContact SG-CB 3.2Å; C52-C93 CovalentContact SG-SG 2.03Å; C52-C93 PolarHBondContact SG-SG 3.46Å; C52-W98 HydrophobicContact CB-CD2 3.99Å; C52-W98 HydrophobicContact CB-CG 4.45Å; C52-W98 HydrophobicContact CB-CH2 4.27Å; C52-W98 HydrophobicContact CB-CZ2 3.68Å
53	S	88.2	Confident	81.6	Confident	92 Å²	92	82.7 Å²	82.7	64%	0.643	43%	0.425	S	S	*	.	P	Polyproline II helix	trans	-69.3	147.9	174.6	-67.3	0	0	0	0	110.9	W98	S53-W98 PolarHBondContact O-NE1 3.48Å
54	G	86.8	Confident	81.8	Confident	22 Å²	22	73.5 Å²	73.5	23%	0.227	39%	0.392	C	S	.	.	P	Polyproline II helix	trans	-69	136.8	175.3	0	0	0	0	0	110.6	W62	G54-W62 CarbonylContact C-O 3.48Å; G54-W62 WeakPolarHBondContact CA-O 3.46Å
55	V	90.1	Very high	82.2	Confident	59 Å²	59	69.5 Å²	69.5	36%	0.358	37%	0.365	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-141.9	143.6	-170.3	66	0	0	0	0	110.8	W62	V55-W62 HydrophobicContact CG1-CB 4.01Å; V55-W62 HydrophobicContact CG1-CG 4.37Å; V55-W62 PolarHBondContact N-O 3.23Å; V55-W62 WeakPolarHBondContact O-CB 3.45Å; V55-W62 PolarHBondContact O-N 3.01Å
56	W	88.6	Confident	82.9	Confident	41 Å²	41	69.7 Å²	69.7	16%	0.155	37%	0.368	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-92.4	122	166.3	177	-112.7	0	0	0	108.6	I31 E34 E35 C38 I59 T60 C61	I31-W56 HydrophobicContact CG2-CZ2 4.04Å; E34-W56 HydrophobicContact CB-CH2 3.71Å; E34-W56 HydrophobicContact CB-CZ3 4.22Å; E35-W56 HydrophobicContact CB-CD2 4.23Å; E35-W56 HydrophobicContact CB-CH2 4.41Å; E35-W56 HydrophobicContact CB-CZ2 3.74Å; E35-W56 HydrophobicContact CG-CD2 4.28Å; E35-W56 HydrophobicContact CG-CG 4.21Å; C38-W56 HydrophobicContact CB-CD2 4.42Å; C38-W56 HydrophobicContact CB-CE3 3.67Å; C38-W56 HydrophobicContact CB-CZ3 4.16Å; W56-I59 VanDerWaalsContact CH2-C 3.42Å; W56-I59 VanDerWaalsContact CH2-O 3.24Å; W56-I59 WeakPolarHBondContact CH2-O 3.41Å; W56-T60 VanDerWaalsContact CE3-C 3.45Å; W56-T60 VanDerWaalsContact CZ3-C 3.48Å; W56-C61 HydrophobicContact CE3-CB 4.01Å; W56-C61 HydrophobicContact CZ3-CB 4.14Å
57	D	84.1	Confident	84.3	Confident	43 Å²	43	67.5 Å²	67.5	23%	0.23	35%	0.354	C	S	.	.			trans	-102.5	36.5	-178.6	73.3	-10.3	0	0	0	113.4	I59 T60 W62 K91	D57-I59 PolarHBondContact O-N 3.21Å; D57-I59 VanDerWaalsContact O-N 3.11Å; D57-I59 PolarHBondContact OD1-N 3.33Å; D57-T60 PolarHBondContact N-O 3.29Å; D57-T60 WeakPolarHBondContact OD1-CA 3.38Å; D57-T60 WeakPolarHBondContact OD1-CB 3.49Å; D57-T60 PolarHBondContact OD1-N 2.81Å; D57-W62 PolarHBondContact OD2-NE1 2.73Å; D57-K91 IonicContact OD2-NZ 3.69Å; D57-K91 PolarHBondContact OD2-NZ 3.47Å
58	N	83	Confident	85.5	Confident	124 Å²	124	64.5 Å²	64.5	66%	0.663	36%	0.357	S	S	*	.	S	Bend	trans	69.7	-14.8	-174.5	-58.3	-21.3	0	0	0	115.7	I31	I31-N58 WeakPolarHBondContact CG2-O 3.41Å
59	I	83.2	Confident	86.9	Confident	68 Å²	68	59.2 Å²	59.2	35%	0.349	34%	0.336	S	S	.	.	S	Bend	trans	-131.2	-39	-177	-58.4	176.2	0	0	0	111.3	W56 D57 P76 F79	W56-I59 VanDerWaalsContact CH2-C 3.42Å; W56-I59 VanDerWaalsContact CH2-O 3.24Å; W56-I59 WeakPolarHBondContact CH2-O 3.41Å; D57-I59 PolarHBondContact O-N 3.21Å; D57-I59 VanDerWaalsContact O-N 3.11Å; D57-I59 PolarHBondContact OD1-N 3.33Å; I59-P76 HydrophobicContact CG2-CB 4.36Å; I59-P76 HydrophobicContact CG2-CG 3.79Å; I59-F79 HydrophobicContact CG2-CE2 4.18Å
60	T	87.3	Confident	88	Confident	10 Å²	10	54.3 Å²	54.3	6%	0.061	32%	0.319	C	S	.	.			trans	-132.4	142.3	-168.9	-51.5	0	0	0	0	111.4	W56 D57 W62 V73 I89	W56-T60 VanDerWaalsContact CE3-C 3.45Å; W56-T60 VanDerWaalsContact CZ3-C 3.48Å; D57-T60 PolarHBondContact N-O 3.29Å; D57-T60 WeakPolarHBondContact OD1-CA 3.38Å; D57-T60 WeakPolarHBondContact OD1-CB 3.49Å; D57-T60 PolarHBondContact OD1-N 2.81Å; T60-W62 HydrophobicContact CG2-CZ2 4.13Å; T60-V73 HydrophobicContact CG2-CB 4.35Å; T60-V73 HydrophobicContact CG2-CG2 3.45Å; T60-V73 VanDerWaalsContact CG2-CG2 3.45Å; T60-I89 HydrophobicContact CG2-CD1 4.2Å
61	C	90.6	Very high	88.6	Confident	28 Å²	28	52.9 Å²	52.9	19%	0.189	31%	0.314	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-90.7	113.8	176.8	-167.3	0	0	0	0	111.5	C38 W56	C38-C61 WeakPolarHBondContact CA-SG 3.23Å; C38-C61 HydrophobicContact CB-CB 3.51Å; C38-C61 WeakPolarHBondContact CB-SG 3.3Å; C38-C61 VanDerWaalsContact SG-CA 3.53Å; C38-C61 WeakPolarHBondContact SG-CB 3.27Å; C38-C61 CovalentContact SG-SG 2.03Å; C38-C61 PolarHBondContact SG-SG 3.33Å; W56-C61 HydrophobicContact CE3-CB 4.01Å; W56-C61 HydrophobicContact CZ3-CB 4.14Å
62	W	90.9	Very high	89	Confident	0 Å²	0	53.5 Å²	53.5	0%	0	31%	0.312	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-94.1	124.4	175.9	-60	94.1	0	0	0	110.7	G54 V55 D57 T60 V71 V73 I89 K91 W98 T101	G54-W62 CarbonylContact C-O 3.48Å; G54-W62 WeakPolarHBondContact CA-O 3.46Å; V55-W62 HydrophobicContact CG1-CB 4.01Å; V55-W62 HydrophobicContact CG1-CG 4.37Å; V55-W62 PolarHBondContact N-O 3.23Å; V55-W62 WeakPolarHBondContact O-CB 3.45Å; V55-W62 PolarHBondContact O-N 3.01Å; D57-W62 PolarHBondContact OD2-NE1 2.73Å; T60-W62 HydrophobicContact CG2-CZ2 4.13Å; W62-V71 HydrophobicContact CE3-CB 4.24Å; W62-V71 HydrophobicContact CE3-CG1 3.97Å; W62-V71 HydrophobicContact CZ3-CG1 4.33Å; W62-V71 WeakPolarHBondContact CZ3-O 3.48Å; W62-V73 HydrophobicContact CH2-CG2 3.79Å; W62-V73 HydrophobicContact CZ2-CG2 4.34Å; W62-V73 HydrophobicContact CZ3-CG2 3.91Å; W62-I89 HydrophobicContact CH2-CD1 4.4Å; W62-I89 HydrophobicContact CH2-CG1 4.21Å; W62-I89 HydrophobicContact CZ2-CD1 4.32Å; W62-K91 HydrophobicContact CD2-CB 4.38Å; W62-K91 HydrophobicContact CD2-CD 3.67Å; W62-K91 HydrophobicContact CD2-CG 4.16Å; W62-K91 VanDerWaalsContact CE2-CD 3.48Å; W62-K91 HydrophobicContact CE3-CB 3.86Å; W62-K91 HydrophobicContact CE3-CD 4.03Å; W62-K91 HydrophobicContact CE3-CG 4.02Å; W62-K91 HydrophobicContact CG-CD 4.23Å; W62-K91 HydrophobicContact CH2-CB 4.04Å; W62-K91 HydrophobicContact CH2-CD 4.05Å; W62-K91 HydrophobicContact CH2-CG 3.57Å; W62-K91 HydrophobicContact CZ2-CD 3.69Å; W62-K91 VanDerWaalsContact CZ2-CE 3.46Å; W62-K91 HydrophobicContact CZ2-CG 3.7Å; W62-K91 HydrophobicContact CZ3-CB 3.68Å; W62-K91 HydrophobicContact CZ3-CD 4.21Å; W62-K91 HydrophobicContact CZ3-CG 3.74Å; W62-W98 HydrophobicContact CB-CZ2 4.27Å; W62-T101 HydrophobicContact CH2-CG2 4.26Å; W62-T101 HydrophobicContact CZ2-CG2 3.74Å
63	R	90	Very high	89.1	Confident	145 Å²	145	54.4 Å²	54.4	55%	0.547	32%	0.317	S	S	.	.	P	Polyproline II helix	trans	-77.9	148.1	176.9	-64.6	-179.2	-174.6	168.8	1.8	110.5	L41 W98	L41-R63 HydrophobicContact CD2-CG 4.19Å; R63-W98 WeakPolarHBondContact O-CH2 3.27Å; R63-W98 WeakPolarHBondContact O-CZ2 3.31Å
64	P	89.7	Confident	89.1	Confident	18 Å²	18	54.5 Å²	54.5	12%	0.117	32%	0.315	C	S	.	.	P	Polyproline II helix	trans	-54.8	138.9	173.4	-22.1	31.1	0	0	0	112.6	K50 C52	K50-P64 HydrophobicContact CB-CB 4.07Å; K50-P64 VanDerWaalsContact CD-C 3.5Å; K50-P64 HydrophobicContact CD-CB 3.88Å; K50-P64 WeakPolarHBondContact CD-O 3.3Å; K50-P64 HydrophobicContact CG-CB 4.29Å; K50-P64 PolarHBondContact NZ-O 3.42Å; C52-P64 VanDerWaalsContact O-CA 3.25Å; C52-P64 WeakPolarHBondContact O-CA 3.49Å
65	A	89.8	Confident	89	Confident	0 Å²	0	54.4 Å²	54.4	0%	0	31%	0.311	C	S	.	.	B	Isolated β-bridge	trans	-141.7	155	-175.4	0	0	0	0	0	112.7	A51 C52 E69 V71 C93 W98	A51-A65 PolarHBondContact N-O 2.87Å; C52-A65 PolarHBondContact N-O 3.08Å; C52-A65 PolarHBondContact O-N 2.86Å; A65-E69 WeakPolarHBondContact CA-OE2 3.5Å; A65-E69 HydrophobicContact CB-CB 4.1Å; A65-V71 HydrophobicContact CB-CG2 3.69Å; A65-C93 HydrophobicContact CB-CB 3.96Å; A65-C93 PolarHBondContact O-SG 3.17Å; A65-W98 HydrophobicContact CB-CH2 3.53Å; A65-W98 HydrophobicContact CB-CZ2 4.26Å; A65-W98 HydrophobicContact CB-CZ3 4.19Å
66	N	89.9	Confident	88.5	Confident	66 Å²	66	52.5 Å²	52.5	35%	0.353	30%	0.3	S	S	.	.			trans	-84.9	157.7	174.6	-61.6	-55	0	0	0	111.5	G68 E69 C93	N66-G68 PolarHBondContact O-N 3.1Å; N66-E69 HydrophobicContact CB-CG 4.07Å; N66-E69 PolarHBondContact N-OE2 3.36Å; N66-E69 PolarHBondContact ND2-OE1 3.12Å; N66-E69 WeakPolarHBondContact O-CB 3.21Å; N66-E69 PolarHBondContact O-N 2.84Å; N66-C93 VanDerWaalsContact C-SG 3.52Å; N66-C93 VanDerWaalsContact O-CB 3.25Å; N66-C93 WeakPolarHBondContact O-CB 3.2Å; N66-C93 PolarHBondContact O-SG 3.05Å; N66-C93 VanDerWaalsContact O-SG 3.42Å
67	V	91.2	Very high	87.9	Confident	87 Å²	87	58.3 Å²	58.3	53%	0.527	33%	0.327	S	S	.	.	T	Hydrogen-bonded Turn	trans	-56.7	127.4	175.4	-176	0	0	0	0	109.7	A51	A51-V67 HydrophobicContact CB-CB 4.47Å; A51-V67 HydrophobicContact CB-CG2 3.35Å
68	G	90.8	Very high	87.2	Confident	66 Å²	66	56.8 Å²	56.8	68%	0.68	32%	0.319	S	S	*	.	T	Hydrogen-bonded Turn	trans	92.9	-8.9	-176.7	0	0	0	0	0	114.8	N66 C93	N66-G68 PolarHBondContact O-N 3.1Å; G68-C93 PolarHBondContact N-O 3.43Å
69	E	91.6	Very high	86.5	Confident	79 Å²	79	52.5 Å²	52.5	37%	0.369	29%	0.294	S	S	.	.	P	Polyproline II helix	trans	-81.2	137.3	174.1	-69.6	179	175.2	0	0	111.5	A65 N66 C93	A65-E69 WeakPolarHBondContact CA-OE2 3.5Å; A65-E69 HydrophobicContact CB-CB 4.1Å; N66-E69 HydrophobicContact CB-CG 4.07Å; N66-E69 PolarHBondContact N-OE2 3.36Å; N66-E69 PolarHBondContact ND2-OE1 3.12Å; N66-E69 WeakPolarHBondContact O-CB 3.21Å; N66-E69 PolarHBondContact O-N 2.84Å; E69-C93 PolarHBondContact O-N 3.25Å
70	T	92.4	Very high	85.5	Confident	76 Å²	76	52.8 Å²	52.8	47%	0.466	30%	0.302	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-99.5	122.5	169.2	-54.7	0	0	0	0	109.3	K91 N92 F102	T70-K91 WeakPolarHBondContact CA-O 3.48Å; T70-N92 VanDerWaalsContact CB-OD1 3.3Å; T70-N92 WeakPolarHBondContact CB-OD1 3.45Å; T70-N92 VanDerWaalsContact CG2-OD1 3.23Å; T70-N92 WeakPolarHBondContact CG2-OD1 3.38Å; T70-N92 PolarHBondContact OG1-OD1 2.94Å; T70-F102 HydrophobicContact CG2-CZ 3.96Å
71	V	91.6	Very high	84.1	Confident	22 Å²	22	56.8 Å²	56.8	13%	0.133	32%	0.323	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-95.8	123.9	171.8	177.4	0	0	0	0	108.4	W62 A65 V73 S90 K91 W98	W62-V71 HydrophobicContact CE3-CB 4.24Å; W62-V71 HydrophobicContact CE3-CG1 3.97Å; W62-V71 HydrophobicContact CZ3-CG1 4.33Å; W62-V71 WeakPolarHBondContact CZ3-O 3.48Å; A65-V71 HydrophobicContact CB-CG2 3.69Å; V71-V73 HydrophobicContact CG1-CG1 4.28Å; V71-S90 CarbonylContact O-C 3.55Å; V71-S90 WeakPolarHBondContact O-CA 3.44Å; V71-K91 PolarHBondContact N-O 3.5Å; V71-K91 PolarHBondContact O-N 3.04Å; V71-W98 HydrophobicContact CB-CH2 4.19Å; V71-W98 HydrophobicContact CB-CZ3 4.18Å; V71-W98 HydrophobicContact CG2-CH2 3.65Å; V71-W98 HydrophobicContact CG2-CZ3 3.96Å
72	T	91.7	Very high	82.7	Confident	75 Å²	75	61.9 Å²	61.9	46%	0.46	34%	0.342	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-116.1	131.2	178.5	-57.7	0	0	0	0	109.3	N88 I89 S90	T72-N88 HydrophobicContact CG2-CB 3.72Å; T72-I89 WeakPolarHBondContact CA-O 3.29Å; T72-S90 WeakPolarHBondContact CB-OG 3.23Å; T72-S90 WeakPolarHBondContact CG2-OG 3.31Å; T72-S90 PolarHBondContact OG1-OG 3.01Å
73	V	89.6	Confident	81.3	Confident	21 Å²	21	64.3 Å²	64.3	13%	0.127	35%	0.352	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-130	145.6	179.9	-65.6	0	0	0	0	109.6	T60 W62 V71 N88 I89	T60-V73 HydrophobicContact CG2-CB 4.35Å; T60-V73 HydrophobicContact CG2-CG2 3.45Å; T60-V73 VanDerWaalsContact CG2-CG2 3.45Å; W62-V73 HydrophobicContact CH2-CG2 3.79Å; W62-V73 HydrophobicContact CZ2-CG2 4.34Å; W62-V73 HydrophobicContact CZ3-CG2 3.91Å; V71-V73 HydrophobicContact CG1-CG1 4.28Å; V73-N88 WeakPolarHBondContact O-CA 3.46Å; V73-I89 HydrophobicContact CG2-CD1 4.02Å; V73-I89 HydrophobicContact CG2-CG1 3.54Å; V73-I89 PolarHBondContact N-O 3.17Å; V73-I89 PolarHBondContact O-N 3.37Å
74	P	87.6	Confident	79.7	Confident	94 Å²	94	63.5 Å²	63.5	61%	0.61	37%	0.369	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-64.8	154.4	175.1	28.8	-34.6	0	0	0	110.5
75	C	85.2	Confident	78.5	Confident	21 Å²	21	68.9 Å²	68.9	14%	0.142	39%	0.39	C	S	.	.	P	Polyproline II helix	trans	-52	133.2	172.8	-76.9	0	0	0	0	110.5	K77 G87 C109	C75-K77 PolarHBondContact O-N 3.49Å; C75-G87 PolarHBondContact N-O 2.9Å; C75-G87 PolarHBondContact SG-O 3.25Å; C75-G87 VanDerWaalsContact SG-O 3.36Å; C75-C109 HydrophobicContact CB-CB 3.87Å; C75-C109 WeakPolarHBondContact CB-SG 3.37Å; C75-C109 WeakPolarHBondContact SG-CA 3.48Å; C75-C109 WeakPolarHBondContact SG-CB 3.42Å; C75-C109 CovalentContact SG-SG 2.04Å; C75-C109 PolarHBondContact SG-SG 2.93Å
76	P	80.2	Confident	77.6	Confident	19 Å²	19	74 Å²	74	12%	0.123	43%	0.433	C	S	.	.	P	Polyproline II helix	trans	-52.2	136.2	178.6	-26.1	31.6	0	0	0	111.3	I59 V78 F79	I59-P76 HydrophobicContact CG2-CB 4.36Å; I59-P76 HydrophobicContact CG2-CG 3.79Å; P76-V78 PolarHBondContact O-N 2.96Å; P76-F79 HydrophobicContact CB-CD2 3.87Å; P76-F79 HydrophobicContact CB-CE2 4.17Å; P76-F79 HydrophobicContact CG-CD2 3.98Å; P76-F79 HydrophobicContact CG-CE2 3.98Å; P76-F79 PolarHBondContact O-N 3.39Å
77	K	75.2	Confident	77.1	Confident	163 Å²	163	71.5 Å²	71.5	71%	0.709	42%	0.422	S	S	*	.	H	α-helix	trans	-57	-25.4	-179.1	-69.8	-177	179.8	177.5	0	112.9	C75 F79 S80	C75-K77 PolarHBondContact O-N 3.49Å; K77-F79 PolarHBondContact O-N 3.5Å; K77-S80 WeakPolarHBondContact O-CA 3.41Å; K77-S80 VanDerWaalsContact O-CB 3.31Å; K77-S80 WeakPolarHBondContact O-CB 3.23Å; K77-S80 PolarHBondContact O-N 3.1Å; K77-S80 PolarHBondContact O-OG 2.82Å
78	V	69.5	Low	77	Confident	11 Å²	11	71.9 Å²	71.9	7%	0.067	42%	0.421	C	S	.	.	H	α-helix	trans	-55	-37.1	174.9	-172.1	0	0	0	0	111.4	F27 E30 I31 P76 F82	F27-V78 HydrophobicContact CD2-CG1 3.15Å; F27-V78 HydrophobicContact CE2-CB 4.41Å; F27-V78 HydrophobicContact CE2-CG1 3.06Å; F27-V78 HydrophobicContact CG-CG1 4.11Å; F27-V78 HydrophobicContact CZ-CG1 3.93Å; E30-V78 HydrophobicContact CB-CG2 4.09Å; I31-V78 HydrophobicContact CG1-CG2 4.41Å; P76-V78 PolarHBondContact O-N 2.96Å; V78-F82 VanDerWaalsContact O-CD2 3.32Å; V78-F82 WeakPolarHBondContact O-CD2 3.47Å
79	F	68.1	Low	76.9	Confident	34 Å²	34	68.8 Å²	68.8	15%	0.149	39%	0.389	C	S	.	.	H	α-helix	trans	-76	-24.2	174.7	-64.4	-72.8	0	0	0	113.2	I59 P76 K77 N81 F82 Y83 F105 C109	I59-F79 HydrophobicContact CG2-CE2 4.18Å; P76-F79 HydrophobicContact CB-CD2 3.87Å; P76-F79 HydrophobicContact CB-CE2 4.17Å; P76-F79 HydrophobicContact CG-CD2 3.98Å; P76-F79 HydrophobicContact CG-CE2 3.98Å; P76-F79 PolarHBondContact O-N 3.39Å; K77-F79 PolarHBondContact O-N 3.5Å; F79-N81 PolarHBondContact O-N 3Å; F79-F82 PolarHBondContact O-N 3.32Å; F79-Y83 PolarHBondContact O-N 3.28Å; F79-F105 HydrophobicContact CE2-CD1 4.26Å; F79-C109 HydrophobicContact CB-CB 4.44Å; F79-C109 HydrophobicContact CG-CB 4.47Å
80	S	63.7	Low	76.9	Confident	73 Å²	73	65.7 Å²	65.7	51%	0.51	38%	0.376	S	S	.	.	H	α-helix	trans	-65.8	-24.3	178.7	76.1	0	0	0	0	113.3	K77 F82 Y83	K77-S80 WeakPolarHBondContact O-CA 3.41Å; K77-S80 VanDerWaalsContact O-CB 3.31Å; K77-S80 WeakPolarHBondContact O-CB 3.23Å; K77-S80 PolarHBondContact O-N 3.1Å; K77-S80 PolarHBondContact O-OG 2.82Å; S80-F82 VanDerWaalsContact C-N 3.27Å; S80-F82 PolarHBondContact O-N 3.05Å; S80-Y83 WeakPolarHBondContact CA-O 3.39Å
81	N	57.8	Low	76.9	Confident	95 Å²	95	63 Å²	63	51%	0.508	36%	0.358	S	S	.	.	T	Hydrogen-bonded Turn	trans	-70	-24.9	173.3	-69.8	-20.1	0	0	0	112.5	E30 F79	E30-N81 PolarHBondContact OE2-ND2 3.45Å; F79-N81 PolarHBondContact O-N 3Å
82	F	59.6	Low	76.9	Confident	134 Å²	134	64.6 Å²	64.6	59%	0.588	37%	0.366	S	S	*	.	T	Hydrogen-bonded Turn	trans	-102.5	-34.8	-178.8	-62.3	-80	0	0	0	112.2	F27 V78 F79 S80	F27-F82 HydrophobicContact CD2-CE2 4.31Å; V78-F82 VanDerWaalsContact O-CD2 3.32Å; V78-F82 WeakPolarHBondContact O-CD2 3.47Å; F79-F82 PolarHBondContact O-N 3.32Å; S80-F82 VanDerWaalsContact C-N 3.27Å; S80-F82 PolarHBondContact O-N 3.05Å
83	Y	61.2	Low	77	Confident	51 Å²	51	61.1 Å²	61.1	20%	0.2	34%	0.344	C	S	.	.			trans	-142.7	130.6	-173.2	-49.4	-76.4	0	0	0	111.5	F79 S80 K85 Y111 D116	F79-Y83 PolarHBondContact O-N 3.28Å; S80-Y83 WeakPolarHBondContact CA-O 3.39Å; Y83-K85 VanDerWaalsContact C-N 3.25Å; Y83-K85 PolarHBondContact O-N 2.98Å; Y83-Y111 HydrophobicContact CE2-CD2 4.2Å; Y83-D116 PolarHBondContact OH-OD2 3.2Å
84	S	57.9	Low	77	Confident	129 Å²	129	62.7 Å²	62.7	90%	0.902	35%	0.354	S	S	*	.			trans	-84.9	19.2	-171.5	46.8	0	0	0	0	114.6
85	K	64.7	Low	77.1	Confident	130 Å²	130	63 Å²	63	57%	0.565	36%	0.358	S	S	*	.			trans	-93.6	110.2	-179	-158.5	179.6	178.8	-167.6	0	110.4	Y83 G87 D107	Y83-K85 VanDerWaalsContact C-N 3.25Å; Y83-K85 PolarHBondContact O-N 2.98Å; K85-G87 VanDerWaalsContact C-N 3.3Å; K85-G87 PolarHBondContact O-N 3.48Å; K85-D107 PolarHBondContact NZ-O 3.02Å
86	A	70.9	Confident	77.3	Confident	109 Å²	109	69.3 Å²	69.3	90%	0.901	39%	0.391	S	S	*	.			trans	-72.2	86.1	169.7	0	0	0	0	0	109.6
87	G	79.3	Confident	77.7	Confident	12 Å²	12	69.6 Å²	69.6	12%	0.124	40%	0.397	C	S	.	.			trans	-99	168.6	174.3	0	0	0	0	0	113	C75 K85 A108	C75-G87 PolarHBondContact N-O 2.9Å; C75-G87 PolarHBondContact SG-O 3.25Å; C75-G87 VanDerWaalsContact SG-O 3.36Å; K85-G87 VanDerWaalsContact C-N 3.3Å; K85-G87 PolarHBondContact O-N 3.48Å; G87-A108 WeakPolarHBondContact CA-O 3.38Å
88	N	87.9	Confident	78.4	Confident	96 Å²	96	64.7 Å²	64.7	51%	0.513	37%	0.374	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-125.1	142.7	172.5	-66.2	-24	0	0	0	109.3	T72 V73	T72-N88 HydrophobicContact CG2-CB 3.72Å; V73-N88 WeakPolarHBondContact O-CA 3.46Å
89	I	88.8	Confident	79.4	Confident	0 Å²	0	65.7 Å²	65.7	0%	0	38%	0.381	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-116.5	148.2	173.3	57.7	178	0	0	0	109.4	T60 W62 T72 V73 F105 A108	T60-I89 HydrophobicContact CG2-CD1 4.2Å; W62-I89 HydrophobicContact CH2-CD1 4.4Å; W62-I89 HydrophobicContact CH2-CG1 4.21Å; W62-I89 HydrophobicContact CZ2-CD1 4.32Å; T72-I89 WeakPolarHBondContact CA-O 3.29Å; V73-I89 HydrophobicContact CG2-CD1 4.02Å; V73-I89 HydrophobicContact CG2-CG1 3.54Å; V73-I89 PolarHBondContact N-O 3.17Å; V73-I89 PolarHBondContact O-N 3.37Å; I89-F105 HydrophobicContact CD1-CD1 4.15Å; I89-F105 HydrophobicContact CD1-CE1 3.34Å; I89-F105 HydrophobicContact CD1-CZ 3.7Å; I89-F105 HydrophobicContact CG2-CD1 4.41Å; I89-A108 HydrophobicContact CG2-CB 3.61Å
90	S	91.6	Very high	80.4	Confident	14 Å²	14	72.3 Å²	72.3	10%	0.098	41%	0.413	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-133.2	149.8	-175	-60.8	0	0	0	0	112.4	V71 T72 T101 F102	V71-S90 CarbonylContact O-C 3.55Å; V71-S90 WeakPolarHBondContact O-CA 3.44Å; T72-S90 WeakPolarHBondContact CB-OG 3.23Å; T72-S90 WeakPolarHBondContact CG2-OG 3.31Å; T72-S90 PolarHBondContact OG1-OG 3.01Å; S90-T101 WeakPolarHBondContact O-CA 3.43Å; S90-F102 WeakPolarHBondContact CA-O 3.26Å; S90-F102 WeakPolarHBondContact CB-O 3.49Å; S90-F102 PolarHBondContact N-O 3.17Å; S90-F102 WeakPolarHBondContact O-CD1 3.11Å; S90-F102 PolarHBondContact O-N 2.92Å
91	K	92.3	Very high	81.5	Confident	21 Å²	21	70.7 Å²	70.7	9%	0.091	40%	0.4	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-129.7	143.7	165.4	-75.6	-173.8	-173.6	170.4	0	110	D57 W62 T70 V71 W98 S99 T101	D57-K91 IonicContact OD2-NZ 3.69Å; D57-K91 PolarHBondContact OD2-NZ 3.47Å; W62-K91 HydrophobicContact CD2-CB 4.38Å; W62-K91 HydrophobicContact CD2-CD 3.67Å; W62-K91 HydrophobicContact CD2-CG 4.16Å; W62-K91 VanDerWaalsContact CE2-CD 3.48Å; W62-K91 HydrophobicContact CE3-CB 3.86Å; W62-K91 HydrophobicContact CE3-CD 4.03Å; W62-K91 HydrophobicContact CE3-CG 4.02Å; W62-K91 HydrophobicContact CG-CD 4.23Å; W62-K91 HydrophobicContact CH2-CB 4.04Å; W62-K91 HydrophobicContact CH2-CD 4.05Å; W62-K91 HydrophobicContact CH2-CG 3.57Å; W62-K91 HydrophobicContact CZ2-CD 3.69Å; W62-K91 VanDerWaalsContact CZ2-CE 3.46Å; W62-K91 HydrophobicContact CZ2-CG 3.7Å; W62-K91 HydrophobicContact CZ3-CB 3.68Å; W62-K91 HydrophobicContact CZ3-CD 4.21Å; W62-K91 HydrophobicContact CZ3-CG 3.74Å; T70-K91 WeakPolarHBondContact CA-O 3.48Å; V71-K91 PolarHBondContact N-O 3.5Å; V71-K91 PolarHBondContact O-N 3.04Å; K91-W98 HydrophobicContact CB-CE3 3.74Å; K91-W98 HydrophobicContact CB-CZ3 4.11Å; K91-W98 HydrophobicContact CD-CB 4.4Å; K91-W98 HydrophobicContact CD-CE3 4.47Å; K91-S99 WeakPolarHBondContact CD-O 3.24Å; K91-T101 HydrophobicContact CD-CG2 4.18Å; K91-T101 HydrophobicContact CG-CG2 3.92Å
92	N	92.3	Very high	82.9	Confident	54 Å²	54	70.1 Å²	70.1	29%	0.289	39%	0.393	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.7	139.2	173.9	-67.1	-25.3	0	0	0	110	T70 S99 F102	T70-N92 VanDerWaalsContact CB-OD1 3.3Å; T70-N92 WeakPolarHBondContact CB-OD1 3.45Å; T70-N92 VanDerWaalsContact CG2-OD1 3.23Å; T70-N92 WeakPolarHBondContact CG2-OD1 3.38Å; T70-N92 PolarHBondContact OG1-OD1 2.94Å; N92-S99 PolarHBondContact N-OG 3.38Å; N92-S99 PolarHBondContact O-N 2.8Å; N92-F102 HydrophobicContact CB-CE1 4.4Å; N92-F102 WeakPolarHBondContact ND2-CE1 3.25Å; N92-F102 VanDerWaalsContact OD1-CZ 3.31Å; N92-F102 WeakPolarHBondContact OD1-CZ 3.48Å
93	C	92.7	Very high	84.1	Confident	2 Å²	2	66.7 Å²	66.7	1%	0.014	38%	0.384	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-86.4	113.4	166.9	178.6	0	0	0	0	109.7	C52 A65 N66 G68 E69 W98	C52-C93 HydrophobicContact CB-CB 3.79Å; C52-C93 WeakPolarHBondContact CB-SG 3.49Å; C52-C93 PolarHBondContact N-SG 3.01Å; C52-C93 WeakPolarHBondContact SG-CA 3.19Å; C52-C93 WeakPolarHBondContact SG-CB 3.2Å; C52-C93 CovalentContact SG-SG 2.03Å; C52-C93 PolarHBondContact SG-SG 3.46Å; A65-C93 HydrophobicContact CB-CB 3.96Å; A65-C93 PolarHBondContact O-SG 3.17Å; N66-C93 VanDerWaalsContact C-SG 3.52Å; N66-C93 VanDerWaalsContact O-CB 3.25Å; N66-C93 WeakPolarHBondContact O-CB 3.2Å; N66-C93 PolarHBondContact O-SG 3.05Å; N66-C93 VanDerWaalsContact O-SG 3.42Å; G68-C93 PolarHBondContact N-O 3.43Å; E69-C93 PolarHBondContact O-N 3.25Å; C93-W98 HydrophobicContact CB-CE3 4.46Å; C93-W98 HydrophobicContact CB-CZ3 4.25Å
94	T	91.3	Very high	85.1	Confident	55 Å²	55	68.6 Å²	68.6	34%	0.337	40%	0.398	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-102.9	170.1	176.6	71.8	0	0	0	0	110.6	D96 G97	T94-D96 PolarHBondContact O-N 3.34Å; T94-D96 PolarHBondContact OG1-N 3.42Å; T94-G97 WeakPolarHBondContact CA-O 3.24Å; T94-G97 WeakPolarHBondContact CB-O 3.37Å; T94-G97 PolarHBondContact N-O 3.48Å; T94-G97 PolarHBondContact O-N 2.91Å; T94-G97 VanDerWaalsContact O-N 3.15Å; T94-G97 PolarHBondContact OG1-N 2.9Å; T94-G97 PolarHBondContact OG1-O 3.42Å
95	S	89.6	Confident	86	Confident	99 Å²	99	64.3 Å²	64.3	69%	0.692	36%	0.363	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.2	-25.1	173.4	51.6	0	0	0	0	113
96	D	89	Confident	86.5	Confident	155 Å²	155	61.1 Å²	61.1	83%	0.829	35%	0.354	S	S	*	.	T	Hydrogen-bonded Turn	trans	-94.1	-1.2	-178.4	-56.2	-30.5	0	0	0	112.5	T94	T94-D96 PolarHBondContact O-N 3.34Å; T94-D96 PolarHBondContact OG1-N 3.42Å
97	G	88.4	Confident	86.7	Confident	24 Å²	24	61 Å²	61	25%	0.247	34%	0.339	C	S	.	.	E	Extended strand (participates in β ladder)	trans	118.8	-157.9	-178.5	0	0	0	0	0	113.8	T94	T94-G97 WeakPolarHBondContact CA-O 3.24Å; T94-G97 WeakPolarHBondContact CB-O 3.37Å; T94-G97 PolarHBondContact N-O 3.48Å; T94-G97 PolarHBondContact O-N 2.91Å; T94-G97 VanDerWaalsContact O-N 3.15Å; T94-G97 PolarHBondContact OG1-N 2.9Å; T94-G97 PolarHBondContact OG1-O 3.42Å
98	W	89.8	Confident	86.7	Confident	60 Å²	60	60.9 Å²	60.9	23%	0.227	34%	0.337	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-71.4	134.4	179.3	-72.2	110.8	0	0	0	112	C52 S53 W62 R63 A65 V71 K91 C93	C52-W98 HydrophobicContact CB-CD2 3.99Å; C52-W98 HydrophobicContact CB-CG 4.45Å; C52-W98 HydrophobicContact CB-CH2 4.27Å; C52-W98 HydrophobicContact CB-CZ2 3.68Å; S53-W98 PolarHBondContact O-NE1 3.48Å; W62-W98 HydrophobicContact CB-CZ2 4.27Å; R63-W98 WeakPolarHBondContact O-CH2 3.27Å; R63-W98 WeakPolarHBondContact O-CZ2 3.31Å; A65-W98 HydrophobicContact CB-CH2 3.53Å; A65-W98 HydrophobicContact CB-CZ2 4.26Å; A65-W98 HydrophobicContact CB-CZ3 4.19Å; V71-W98 HydrophobicContact CB-CH2 4.19Å; V71-W98 HydrophobicContact CB-CZ3 4.18Å; V71-W98 HydrophobicContact CG2-CH2 3.65Å; V71-W98 HydrophobicContact CG2-CZ3 3.96Å; K91-W98 HydrophobicContact CB-CE3 3.74Å; K91-W98 HydrophobicContact CB-CZ3 4.11Å; K91-W98 HydrophobicContact CD-CB 4.4Å; K91-W98 HydrophobicContact CD-CE3 4.47Å; C93-W98 HydrophobicContact CB-CE3 4.46Å; C93-W98 HydrophobicContact CB-CZ3 4.25Å
99	S	90.7	Very high	86.3	Confident	32 Å²	32	56.4 Å²	56.4	22%	0.224	31%	0.313	C	S	.	.	P	Polyproline II helix	trans	-70.9	168.2	169.7	76.1	0	0	0	0	112.1	K91 N92	K91-S99 WeakPolarHBondContact CD-O 3.24Å; N92-S99 PolarHBondContact N-OG 3.38Å; N92-S99 PolarHBondContact O-N 2.8Å
100	E	88	Confident	85.3	Confident	174 Å²	174	57.3 Å²	57.3	81%	0.813	32%	0.322	S	S	*	.	P	Polyproline II helix	trans	-57.7	153.2	164.2	-63.5	-172.7	158.6	0	0	111.1
101	T	87.2	Confident	84	Confident	39 Å²	39	61.2 Å²	61.2	24%	0.239	34%	0.335	C	S	.	.	P	Polyproline II helix	trans	-67.4	133.2	175.2	42.2	0	0	0	0	110.6	W62 S90 K91 F105	W62-T101 HydrophobicContact CH2-CG2 4.26Å; W62-T101 HydrophobicContact CZ2-CG2 3.74Å; S90-T101 WeakPolarHBondContact O-CA 3.43Å; K91-T101 HydrophobicContact CD-CG2 4.18Å; K91-T101 HydrophobicContact CG-CG2 3.92Å; T101-F105 HydrophobicContact CG2-CE2 3.87Å; T101-F105 HydrophobicContact CG2-CZ 4.18Å
102	F	87.7	Confident	82.4	Confident	83 Å²	83	63.6 Å²	63.6	36%	0.364	35%	0.354	S	S	.	.	B	Isolated β-bridge	trans	-139.3	145.6	174.4	65.5	-84.7	0	0	0	110.9	T70 S90 N92	T70-F102 HydrophobicContact CG2-CZ 3.96Å; S90-F102 WeakPolarHBondContact CA-O 3.26Å; S90-F102 WeakPolarHBondContact CB-O 3.49Å; S90-F102 PolarHBondContact N-O 3.17Å; S90-F102 WeakPolarHBondContact O-CD1 3.11Å; S90-F102 PolarHBondContact O-N 2.92Å; N92-F102 HydrophobicContact CB-CE1 4.4Å; N92-F102 WeakPolarHBondContact ND2-CE1 3.25Å; N92-F102 VanDerWaalsContact OD1-CZ 3.31Å; N92-F102 WeakPolarHBondContact OD1-CZ 3.48Å
103	P	85	Confident	80.7	Confident	62 Å²	62	65.3 Å²	65.3	40%	0.403	36%	0.363	S	S	.	.	S	Bend	cis	-60.7	165.8	-17.2	19.2	-18.2	0	0	0	111.5	D107 A108	P103-D107 HydrophobicContact CB-CB 4.44Å; P103-A108 HydrophobicContact CB-CB 4.49Å; P103-A108 HydrophobicContact CG-CB 3.9Å
104	D	81.4	Confident	79	Confident	90 Å²	90	70.4 Å²	70.4	48%	0.481	40%	0.396	S	S	.	.			trans	-53.1	145.1	177.1	-163.8	-46	0	0	0	109.9	V106 D107 A108	D104-V106 PolarHBondContact O-N 3Å; D104-V106 VanDerWaalsContact O-N 3.11Å; D104-V106 PolarHBondContact OD1-N 3.49Å; D104-D107 PolarHBondContact O-N 3.3Å; D104-A108 WeakPolarHBondContact O-CB 3.09Å; D104-A108 PolarHBondContact O-N 3.43Å
105	F	77.3	Confident	77.4	Confident	39 Å²	39	73.8 Å²	73.8	17%	0.171	41%	0.408	C	S	.	.	H	α-helix	trans	-51.2	-35.7	177	-76	-88.6	0	0	0	111.7	F79 I89 T101 C109	F79-F105 HydrophobicContact CE2-CD1 4.26Å; I89-F105 HydrophobicContact CD1-CD1 4.15Å; I89-F105 HydrophobicContact CD1-CE1 3.34Å; I89-F105 HydrophobicContact CD1-CZ 3.7Å; I89-F105 HydrophobicContact CG2-CD1 4.41Å; T101-F105 HydrophobicContact CG2-CE2 3.87Å; T101-F105 HydrophobicContact CG2-CZ 4.18Å; F105-C109 WeakPolarHBondContact O-CA 3.41Å; F105-C109 VanDerWaalsContact O-CB 3.31Å; F105-C109 WeakPolarHBondContact O-CB 3.45Å; F105-C109 PolarHBondContact O-N 3.31Å
106	V	74.7	Confident	76.1	Confident	63 Å²	63	70.4 Å²	70.4	38%	0.382	38%	0.383	S	S	.	.	H	α-helix	trans	-56.3	-51.1	175.7	177.6	0	0	0	0	111.6	D104 G110 Y111	D104-V106 PolarHBondContact O-N 3Å; D104-V106 VanDerWaalsContact O-N 3.11Å; D104-V106 PolarHBondContact OD1-N 3.49Å; V106-G110 CarbonylContact O-C 3.57Å; V106-G110 VanDerWaalsContact O-CA 3.27Å; V106-G110 WeakPolarHBondContact O-CA 3.31Å; V106-G110 PolarHBondContact O-N 3.36Å; V106-Y111 WeakPolarHBondContact CG1-O 3.46Å; V106-Y111 HydrophobicContact CG2-CD1 4.14Å; V106-Y111 PolarHBondContact O-N 3.03Å; V106-Y111 VanDerWaalsContact O-N 3.13Å
107	D	76.6	Confident	75.1	Confident	108 Å²	108	68.7 Å²	68.7	58%	0.578	37%	0.37	S	S	*	.	H	α-helix	trans	-78.7	-39.3	-175.7	-66.1	-37.4	0	0	0	112.6	K85 P103 D104	K85-D107 PolarHBondContact NZ-O 3.02Å; P103-D107 HydrophobicContact CB-CB 4.44Å; D104-D107 PolarHBondContact O-N 3.3Å
108	A	78.8	Confident	74.3	Confident	9 Å²	9	71.1 Å²	71.1	7%	0.074	38%	0.383	C	S	.	.	H	α-helix	trans	-72	-51.7	-176.2	0	0	0	0	0	111.4	G87 I89 P103 D104	G87-A108 WeakPolarHBondContact CA-O 3.38Å; I89-A108 HydrophobicContact CG2-CB 3.61Å; P103-A108 HydrophobicContact CB-CB 4.49Å; P103-A108 HydrophobicContact CG-CB 3.9Å; D104-A108 WeakPolarHBondContact O-CB 3.09Å; D104-A108 PolarHBondContact O-N 3.43Å
109	C	78.2	Confident	73.3	Confident	2 Å²	2	71 Å²	71	1%	0.014	38%	0.384	C	S	.	.	H	α-helix	trans	-100.5	-6.3	-171.3	-51.8	0	0	0	0	113.1	C75 F79 F105	C75-C109 HydrophobicContact CB-CB 3.87Å; C75-C109 WeakPolarHBondContact CB-SG 3.37Å; C75-C109 WeakPolarHBondContact SG-CA 3.48Å; C75-C109 WeakPolarHBondContact SG-CB 3.42Å; C75-C109 CovalentContact SG-SG 2.04Å; C75-C109 PolarHBondContact SG-SG 2.93Å; F79-C109 HydrophobicContact CB-CB 4.44Å; F79-C109 HydrophobicContact CG-CB 4.47Å; F105-C109 WeakPolarHBondContact O-CA 3.41Å; F105-C109 VanDerWaalsContact O-CB 3.31Å; F105-C109 WeakPolarHBondContact O-CB 3.45Å; F105-C109 PolarHBondContact O-N 3.31Å
110	G	68.8	Low	72.5	Confident	18 Å²	18	73.6 Å²	73.6	19%	0.186	39%	0.394	C	S	.	.			trans	84.5	29.3	171.4	0	0	0	0	0	114.8	V106 S112	V106-G110 CarbonylContact O-C 3.57Å; V106-G110 VanDerWaalsContact O-CA 3.27Å; V106-G110 WeakPolarHBondContact O-CA 3.31Å; V106-G110 PolarHBondContact O-N 3.36Å; G110-S112 VanDerWaalsContact C-N 3.35Å; G110-S112 PolarHBondContact O-N 3.22Å
111	Y	64.1	Low	72.1	Confident	97 Å²	97	69.4 Å²	69.4	38%	0.38	38%	0.38	S	S	.	.			trans	-73.9	87.4	172.6	-175.6	-89.4	0	0	0	109.2	Y83 V106 D113	Y83-Y111 HydrophobicContact CE2-CD2 4.2Å; V106-Y111 WeakPolarHBondContact CG1-O 3.46Å; V106-Y111 HydrophobicContact CG2-CD1 4.14Å; V106-Y111 PolarHBondContact O-N 3.03Å; V106-Y111 VanDerWaalsContact O-N 3.13Å; Y111-D113 HydrophobicContact CE1-CB 4.39Å
112	S	57.9	Low	71.9	Confident	71 Å²	71	69.8 Å²	69.8	50%	0.497	38%	0.379	S	S	.	.			trans	-104.6	104	176.8	53	0	0	0	0	111.3	G110 P114	G110-S112 VanDerWaalsContact C-N 3.35Å; G110-S112 PolarHBondContact O-N 3.22Å; S112-P114 WeakPolarHBondContact O-CD 3.23Å
113	D	58	Low	71.5	Confident	89 Å²	89	71.5 Å²	71.5	48%	0.476	38%	0.384	S	S	.	.	T	Hydrogen-bonded Turn	trans	-65.2	-12	-171.6	-130.1	-22.5	0	0	0	119.9	Y111	Y111-D113 HydrophobicContact CE1-CB 4.39Å
114	P	55.9	Low	71.4	Confident	109 Å²	109	73.6 Å²	73.6	71%	0.708	39%	0.391	S	S	*	.	H	α-helix	trans	-81.1	-28.5	-173.7	-10.7	24.6	0	0	0	115.6	S112	S112-P114 WeakPolarHBondContact O-CD 3.23Å
115	E	57.3	Low	71.6	Confident	126 Å²	126	74.1 Å²	74.1	59%	0.589	39%	0.393	S	S	*	.	H	α-helix	trans	-83.8	-22.7	-174	-72.6	-165.9	176.1	0	0	113.3	S118 K119	E115-S118 PolarHBondContact O-OG 3.09Å; E115-K119 WeakPolarHBondContact O-CG 3.35Å; E115-K119 PolarHBondContact O-N 3.11Å; E115-K119 IonicContact OE2-NZ 3.87Å; E115-K119 PolarHBondContact OE2-NZ 2.88Å
116	D	62.5	Low	72	Confident	29 Å²	29	72.5 Å²	72.5	16%	0.155	39%	0.386	C	S	.	.	H	α-helix	trans	-84.2	-32.1	-167.9	-66.8	-29.7	0	0	0	112.8	Y83 S118 K119 I120	Y83-D116 PolarHBondContact OH-OD2 3.2Å; D116-S118 VanDerWaalsContact C-N 3.31Å; D116-S118 PolarHBondContact O-N 3.41Å; D116-K119 PolarHBondContact O-N 2.65Å; D116-K119 VanDerWaalsContact O-N 3.1Å; D116-K119 IonicContact OD1-NZ 3.11Å; D116-K119 PolarHBondContact OD1-NZ 2.95Å; D116-I120 WeakPolarHBondContact O-CB 3.42Å; D116-I120 WeakPolarHBondContact O-CG1 3.35Å; D116-I120 PolarHBondContact O-N 3.16Å
117	E	67.7	Low	72.6	Confident	119 Å²	119	72 Å²	72	56%	0.556	38%	0.379	S	S	*	.	H	α-helix	trans	-55.3	-44.1	170.9	-78.8	-66	147.9	0	0	112.6	T121	E117-T121 WeakPolarHBondContact O-CB 3.41Å; E117-T121 PolarHBondContact O-N 3.45Å; E117-T121 PolarHBondContact O-OG1 2.88Å
118	S	71.7	Confident	73.1	Confident	74 Å²	74	69.6 Å²	69.6	52%	0.517	37%	0.374	S	S	.	.	H	α-helix	trans	-68.2	-35.8	178.1	77.2	0	0	0	0	112.6	E115 D116 F122	E115-S118 PolarHBondContact O-OG 3.09Å; D116-S118 VanDerWaalsContact C-N 3.31Å; D116-S118 PolarHBondContact O-N 3.41Å; S118-F122 VanDerWaalsContact O-CB 3.3Å; S118-F122 WeakPolarHBondContact O-CB 3.22Å; S118-F122 PolarHBondContact O-N 3.39Å
119	K	70	Confident	73.6	Confident	57 Å²	57	72 Å²	72	25%	0.248	39%	0.385	C	S	.	.	H	α-helix	trans	-71.1	-44.2	177.4	-68.7	171.9	-159.9	152.7	0	110.7	E115 D116 F122 Y123	E115-K119 WeakPolarHBondContact O-CG 3.35Å; E115-K119 PolarHBondContact O-N 3.11Å; E115-K119 IonicContact OE2-NZ 3.87Å; E115-K119 PolarHBondContact OE2-NZ 2.88Å; D116-K119 PolarHBondContact O-N 2.65Å; D116-K119 VanDerWaalsContact O-N 3.1Å; D116-K119 IonicContact OD1-NZ 3.11Å; D116-K119 PolarHBondContact OD1-NZ 2.95Å; K119-F122 WeakPolarHBondContact O-CB 3.38Å; K119-F122 PolarHBondContact O-N 2.81Å; K119-Y123 HydrophobicContact CB-CE2 4.39Å; K119-Y123 WeakPolarHBondContact O-CD2 2.99Å; K119-Y123 PolarHBondContact O-N 3.3Å
120	I	73.7	Confident	74.2	Confident	88 Å²	88	72.7 Å²	72.7	45%	0.451	39%	0.387	S	S	.	.	H	α-helix	trans	-59.7	-50.2	176.7	-67.1	163.4	0	0	0	109.5	D116 F122 Y123 I124	D116-I120 WeakPolarHBondContact O-CB 3.42Å; D116-I120 WeakPolarHBondContact O-CG1 3.35Å; D116-I120 PolarHBondContact O-N 3.16Å; I120-F122 VanDerWaalsContact C-N 3.29Å; I120-F122 PolarHBondContact O-N 2.68Å; I120-Y123 PolarHBondContact O-N 2.9Å; I120-Y123 VanDerWaalsContact O-N 3.14Å; I120-I124 HydrophobicContact CG2-CD1 3.7Å; I120-I124 HydrophobicContact CG2-CG1 4.37Å; I120-I124 VanDerWaalsContact O-CG1 3.31Å; I120-I124 WeakPolarHBondContact O-CG1 3.39Å; I120-I124 PolarHBondContact O-N 2.89Å
121	T	80.3	Confident	75.3	Confident	85 Å²	85	73.8 Å²	73.8	52%	0.521	39%	0.39	S	S	.	.	H	α-helix	trans	-57.7	-42.2	176.4	-58.5	0	0	0	0	111.7	E117 I124 L125	E117-T121 WeakPolarHBondContact O-CB 3.41Å; E117-T121 PolarHBondContact O-N 3.45Å; E117-T121 PolarHBondContact O-OG1 2.88Å; T121-I124 PolarHBondContact O-N 3.32Å; T121-L125 WeakPolarHBondContact O-CB 3.26Å; T121-L125 PolarHBondContact O-N 3.17Å
122	F	81.4	Confident	76.7	Confident	47 Å²	47	74.2 Å²	74.2	21%	0.206	40%	0.399	C	S	.	.	H	α-helix	trans	-60.8	-47.2	175.4	174.8	-96.3	0	0	0	112.2	S118 K119 I120 L125 V126 K354 L358	S118-F122 VanDerWaalsContact O-CB 3.3Å; S118-F122 WeakPolarHBondContact O-CB 3.22Å; S118-F122 PolarHBondContact O-N 3.39Å; K119-F122 WeakPolarHBondContact O-CB 3.38Å; K119-F122 PolarHBondContact O-N 2.81Å; I120-F122 VanDerWaalsContact C-N 3.29Å; I120-F122 PolarHBondContact O-N 2.68Å; F122-L125 PolarHBondContact O-N 3.45Å; F122-V126 HydrophobicContact CD1-CG2 4.08Å; F122-V126 HydrophobicContact CD2-CG2 4.42Å; F122-V126 HydrophobicContact CE1-CG2 3.74Å; F122-V126 HydrophobicContact CE2-CG2 4.11Å; F122-V126 HydrophobicContact CG-CG2 4.41Å; F122-V126 HydrophobicContact CZ-CG2 3.75Å; F122-V126 WeakPolarHBondContact O-CB 3.43Å; F122-V126 WeakPolarHBondContact O-CG2 3.32Å; F122-V126 PolarHBondContact O-N 3.45Å; F122-K354 HydrophobicContact CE1-CB 3.97Å; F122-K354 HydrophobicContact CE1-CG 4.36Å; F122-K354 HydrophobicContact CZ-CB 3.88Å; F122-L358 HydrophobicContact CE2-CD2 4.44Å; F122-L358 HydrophobicContact CZ-CB 4.16Å
123	Y	79.6	Confident	78.4	Confident	119 Å²	119	70.8 Å²	70.8	47%	0.467	38%	0.375	S	S	.	.	H	α-helix	trans	-67.4	-36.2	178.9	-73.4	-63.2	0	0	0	113	K119 I120 V126 K127	K119-Y123 HydrophobicContact CB-CE2 4.39Å; K119-Y123 WeakPolarHBondContact O-CD2 2.99Å; K119-Y123 PolarHBondContact O-N 3.3Å; I120-Y123 PolarHBondContact O-N 2.9Å; I120-Y123 VanDerWaalsContact O-N 3.14Å; Y123-V126 PolarHBondContact O-N 3.49Å; Y123-K127 VanDerWaalsContact O-CB 3.28Å; Y123-K127 WeakPolarHBondContact O-CB 3.36Å; Y123-K127 PolarHBondContact O-N 3.02Å
124	I	83.1	Confident	80.2	Confident	107 Å²	107	67.2 Å²	67.2	55%	0.549	36%	0.355	S	S	.	.	H	α-helix	trans	-62.6	-45.3	173.1	-68.6	169.5	0	0	0	110.4	I120 T121 K127 A128	I120-I124 HydrophobicContact CG2-CD1 3.7Å; I120-I124 HydrophobicContact CG2-CG1 4.37Å; I120-I124 VanDerWaalsContact O-CG1 3.31Å; I120-I124 WeakPolarHBondContact O-CG1 3.39Å; I120-I124 PolarHBondContact O-N 2.89Å; T121-I124 PolarHBondContact O-N 3.32Å; I124-K127 WeakPolarHBondContact O-CB 3.3Å; I124-K127 PolarHBondContact O-N 2.9Å; I124-A128 PolarHBondContact O-N 3.45Å
125	L	86.4	Confident	82	Confident	101 Å²	101	64.2 Å²	64.2	53%	0.529	34%	0.336	S	S	.	.	H	α-helix	trans	-63	-47.2	176.8	179	64.7	0	0	0	111.6	T121 F122 K127 A128 I129	T121-L125 WeakPolarHBondContact O-CB 3.26Å; T121-L125 PolarHBondContact O-N 3.17Å; F122-L125 PolarHBondContact O-N 3.45Å; L125-K127 VanDerWaalsContact C-N 3.27Å; L125-K127 PolarHBondContact O-N 2.96Å; L125-A128 PolarHBondContact O-N 3.41Å; L125-I129 HydrophobicContact CD1-CD1 4.03Å; L125-I129 HydrophobicContact CD1-CG1 4.33Å; L125-I129 HydrophobicContact CG-CD1 3.9Å; L125-I129 VanDerWaalsContact O-CG1 3.3Å; L125-I129 WeakPolarHBondContact O-CG1 3.11Å; L125-I129 PolarHBondContact O-N 3.09Å
126	V	85.6	Confident	83.9	Confident	5 Å²	5	61 Å²	61	3%	0.03	33%	0.325	C	S	.	.	H	α-helix	trans	-55.8	-46.1	175.8	170.4	0	0	0	0	109.9	F122 Y123 I129 Y130 L358 L361	F122-V126 HydrophobicContact CD1-CG2 4.08Å; F122-V126 HydrophobicContact CD2-CG2 4.42Å; F122-V126 HydrophobicContact CE1-CG2 3.74Å; F122-V126 HydrophobicContact CE2-CG2 4.11Å; F122-V126 HydrophobicContact CG-CG2 4.41Å; F122-V126 HydrophobicContact CZ-CG2 3.75Å; F122-V126 WeakPolarHBondContact O-CB 3.43Å; F122-V126 WeakPolarHBondContact O-CG2 3.32Å; F122-V126 PolarHBondContact O-N 3.45Å; Y123-V126 PolarHBondContact O-N 3.49Å; V126-I129 PolarHBondContact O-N 3.15Å; V126-Y130 HydrophobicContact CG1-CD1 4.01Å; V126-Y130 HydrophobicContact CG1-CE1 4.38Å; V126-Y130 WeakPolarHBondContact O-CD1 3.36Å; V126-Y130 PolarHBondContact O-N 2.76Å; V126-L358 HydrophobicContact CG2-CD1 3.64Å; V126-L361 HydrophobicContact CG1-CD2 4.02Å
127	K	86.2	Confident	85.4	Confident	53 Å²	53	59.8 Å²	59.8	23%	0.23	32%	0.319	C	S	.	.	H	α-helix	trans	-56	-54.8	174.9	179.8	173.3	-179.3	-166.3	0	112.6	Y123 I124 L125 I129 Y130 T131 Y184	Y123-K127 VanDerWaalsContact O-CB 3.28Å; Y123-K127 WeakPolarHBondContact O-CB 3.36Å; Y123-K127 PolarHBondContact O-N 3.02Å; I124-K127 WeakPolarHBondContact O-CB 3.3Å; I124-K127 PolarHBondContact O-N 2.9Å; L125-K127 VanDerWaalsContact C-N 3.27Å; L125-K127 PolarHBondContact O-N 2.96Å; K127-I129 VanDerWaalsContact C-N 3.28Å; K127-I129 PolarHBondContact O-N 3.44Å; K127-Y130 HydrophobicContact CB-CE1 3.94Å; K127-Y130 HydrophobicContact CG-CE1 4.27Å; K127-Y130 WeakPolarHBondContact CG-OH 3.42Å; K127-Y130 PolarHBondContact O-N 3.46Å; K127-T131 VanDerWaalsContact O-CB 3.27Å; K127-T131 WeakPolarHBondContact O-CB 3.46Å; K127-T131 PolarHBondContact O-N 2.95Å; K127-T131 PolarHBondContact O-OG1 3.06Å; K127-Y184 HydrophobicContact CD-CD2 4.32Å; K127-Y184 HydrophobicContact CD-CE2 4.14Å
128	A	87.6	Confident	86.8	Confident	57 Å²	57	55.8 Å²	55.8	47%	0.471	30%	0.301	S	S	.	.	H	α-helix	trans	-55.8	-43.5	178.8	0	0	0	0	0	112.4	I124 L125 L132	I124-A128 PolarHBondContact O-N 3.45Å; L125-A128 PolarHBondContact O-N 3.41Å; A128-L132 VanDerWaalsContact O-CB 3.3Å; A128-L132 WeakPolarHBondContact O-CB 3.5Å; A128-L132 PolarHBondContact O-N 3.29Å
129	I	90	Very high	88	Confident	58 Å²	58	58.4 Å²	58.4	30%	0.297	31%	0.307	S	S	.	.	H	α-helix	trans	-66	-49.8	-178.9	-65	166.7	0	0	0	111.4	L125 V126 K127 L132 G133 C362 F366	L125-I129 HydrophobicContact CD1-CD1 4.03Å; L125-I129 HydrophobicContact CD1-CG1 4.33Å; L125-I129 HydrophobicContact CG-CD1 3.9Å; L125-I129 VanDerWaalsContact O-CG1 3.3Å; L125-I129 WeakPolarHBondContact O-CG1 3.11Å; L125-I129 PolarHBondContact O-N 3.09Å; V126-I129 PolarHBondContact O-N 3.15Å; K127-I129 VanDerWaalsContact C-N 3.28Å; K127-I129 PolarHBondContact O-N 3.44Å; I129-L132 PolarHBondContact O-N 2.76Å; I129-G133 PolarHBondContact O-N 3.49Å; I129-C362 HydrophobicContact CG2-CB 4.33Å; I129-C362 WeakPolarHBondContact CG2-SG 3.43Å; I129-F366 HydrophobicContact CG2-CE2 4.34Å
130	Y	90.8	Very high	89.2	Confident	17 Å²	17	56.2 Å²	56.2	7%	0.067	30%	0.299	C	S	.	.	H	α-helix	trans	-71.7	-32.7	-178.3	77.9	-116.5	0	0	0	111.7	V126 K127 G133 Y134 V176 D180 L361 S365	V126-Y130 HydrophobicContact CG1-CD1 4.01Å; V126-Y130 HydrophobicContact CG1-CE1 4.38Å; V126-Y130 WeakPolarHBondContact O-CD1 3.36Å; V126-Y130 PolarHBondContact O-N 2.76Å; K127-Y130 HydrophobicContact CB-CE1 3.94Å; K127-Y130 HydrophobicContact CG-CE1 4.27Å; K127-Y130 WeakPolarHBondContact CG-OH 3.42Å; K127-Y130 PolarHBondContact O-N 3.46Å; Y130-G133 PolarHBondContact O-N 3.3Å; Y130-Y134 AromaticContact CD2-CD2 3.92Å; Y130-Y134 HydrophobicContact CD2-CD2 3.92Å; Y130-Y134 HydrophobicContact CD2-CE2 4.07Å; Y130-Y134 VanDerWaalsContact O-CD2 3.23Å; Y130-Y134 WeakPolarHBondContact O-CD2 3.42Å; Y130-Y134 PolarHBondContact O-N 3.3Å; Y130-V176 HydrophobicContact CD2-CG1 4.49Å; Y130-V176 HydrophobicContact CE2-CG1 4.23Å; Y130-D180 WeakPolarHBondContact CE2-OD2 3.24Å; Y130-D180 VanDerWaalsContact OH-CG 3.32Å; Y130-D180 PolarHBondContact OH-OD1 3.24Å; Y130-D180 VanDerWaalsContact OH-OD1 3.14Å; Y130-D180 PolarHBondContact OH-OD2 2.91Å; Y130-L361 HydrophobicContact CD1-CB 4.47Å; Y130-L361 HydrophobicContact CD1-CD2 3.41Å; Y130-L361 VanDerWaalsContact CD1-CD2 3.41Å; Y130-L361 HydrophobicContact CD1-CG 4Å; Y130-L361 HydrophobicContact CE1-CD2 3.62Å; Y130-L361 HydrophobicContact CG-CD2 4.2Å; Y130-L361 HydrophobicContact CG-CG 4.34Å; Y130-S365 WeakPolarHBondContact O-CB 3.43Å
131	T	91.4	Very high	90.3	Very high	41 Å²	41	52.1 Å²	52.1	25%	0.252	28%	0.278	S	S	.	.	H	α-helix	trans	-63.2	-44.4	175	-61.8	0	0	0	0	110.1	K127 S135 L177	K127-T131 VanDerWaalsContact O-CB 3.27Å; K127-T131 WeakPolarHBondContact O-CB 3.46Å; K127-T131 PolarHBondContact O-N 2.95Å; K127-T131 PolarHBondContact O-OG1 3.06Å; T131-S135 WeakPolarHBondContact O-CB 3.24Å; T131-S135 PolarHBondContact O-N 3.08Å; T131-S135 PolarHBondContact O-OG 3.43Å; T131-L177 HydrophobicContact CG2-CD2 3.88Å
132	L	93.5	Very high	91	Very high	106 Å²	106	49.7 Å²	49.7	56%	0.555	27%	0.266	S	S	*	.	H	α-helix	trans	-59.6	-46.8	172.2	179	65.4	0	0	0	110.9	A128 I129 S135 V136	A128-L132 VanDerWaalsContact O-CB 3.3Å; A128-L132 WeakPolarHBondContact O-CB 3.5Å; A128-L132 PolarHBondContact O-N 3.29Å; I129-L132 PolarHBondContact O-N 2.76Å; L132-S135 PolarHBondContact O-N 2.93Å; L132-V136 HydrophobicContact CD1-CG2 4.23Å; L132-V136 WeakPolarHBondContact O-CG2 3.46Å; L132-V136 PolarHBondContact O-N 2.98Å
133	G	94.2	Very high	91.7	Very high	0 Å²	0	50.5 Å²	50.5	0%	0	28%	0.275	C	S	.	.	H	α-helix	trans	-58.5	-49.3	179	0	0	0	0	0	113.2	I129 Y130 S135 V136 S137 S365	I129-G133 PolarHBondContact O-N 3.49Å; Y130-G133 PolarHBondContact O-N 3.3Å; G133-S135 PolarHBondContact O-N 2.93Å; G133-V136 PolarHBondContact O-N 3.31Å; G133-S137 VanDerWaalsContact O-CB 3.3Å; G133-S137 WeakPolarHBondContact O-CB 3.16Å; G133-S137 PolarHBondContact O-N 3.13Å; G133-S137 PolarHBondContact O-OG 3.24Å; G133-S137 VanDerWaalsContact O-OG 3.11Å; G133-S365 CarbonylContact C-O 3.5Å
134	Y	94.4	Very high	92.3	Very high	13 Å²	13	44.8 Å²	44.8	5%	0.051	25%	0.253	C	S	.	.	H	α-helix	trans	-65.9	-36.5	177.2	-77.9	-59.8	0	0	0	112.6	Y130 S137 L138 A173 V176	Y130-Y134 AromaticContact CD2-CD2 3.92Å; Y130-Y134 HydrophobicContact CD2-CD2 3.92Å; Y130-Y134 HydrophobicContact CD2-CE2 4.07Å; Y130-Y134 VanDerWaalsContact O-CD2 3.23Å; Y130-Y134 WeakPolarHBondContact O-CD2 3.42Å; Y130-Y134 PolarHBondContact O-N 3.3Å; Y134-S137 PolarHBondContact O-N 2.99Å; Y134-L138 WeakPolarHBondContact O-CB 3.25Å; Y134-L138 PolarHBondContact O-N 3.47Å; Y134-A173 HydrophobicContact CD1-CB 3.86Å; Y134-A173 HydrophobicContact CG-CB 4.4Å; Y134-V176 HydrophobicContact CD2-CB 4.32Å; Y134-V176 HydrophobicContact CD2-CG1 3.83Å; Y134-V176 HydrophobicContact CE2-CB 4.17Å; Y134-V176 HydrophobicContact CE2-CG1 3.66Å; Y134-V176 HydrophobicContact CE2-CG2 4.23Å
135	S	95.3	Very high	92.8	Very high	46 Å²	46	40.4 Å²	40.4	32%	0.322	23%	0.232	S	C	.	.	H	α-helix	trans	-63.5	-47	177.1	-58.9	0	0	0	0	111.7	T131 L132 G133 L138 M139	T131-S135 WeakPolarHBondContact O-CB 3.24Å; T131-S135 PolarHBondContact O-N 3.08Å; T131-S135 PolarHBondContact O-OG 3.43Å; L132-S135 PolarHBondContact O-N 2.93Å; G133-S135 PolarHBondContact O-N 2.93Å; S135-L138 PolarHBondContact O-N 3.04Å; S135-M139 WeakPolarHBondContact O-CG 3.4Å; S135-M139 PolarHBondContact O-N 2.79Å
136	V	95.7	Very high	93.2	Very high	59 Å²	59	40.3 Å²	40.3	36%	0.358	23%	0.231	S	C	.	.	H	α-helix	trans	-66.6	-42.4	177.7	175.9	0	0	0	0	111.1	L132 G133 L138 M139 S140 L369	L132-V136 HydrophobicContact CD1-CG2 4.23Å; L132-V136 WeakPolarHBondContact O-CG2 3.46Å; L132-V136 PolarHBondContact O-N 2.98Å; G133-V136 PolarHBondContact O-N 3.31Å; V136-L138 PolarHBondContact O-N 3.35Å; V136-M139 PolarHBondContact O-N 2.96Å; V136-S140 WeakPolarHBondContact O-CB 3.23Å; V136-S140 PolarHBondContact O-N 3.07Å; V136-S140 PolarHBondContact O-OG 3.01Å; V136-L369 HydrophobicContact CG1-CD1 4.13Å; V136-L369 HydrophobicContact CG1-CD2 3.91Å
137	S	95.8	Very high	93.5	Very high	3 Å²	3	41.4 Å²	41.4	2%	0.021	24%	0.236	C	C	.	.	H	α-helix	trans	-59.1	-45.1	173.3	-73.7	0	0	0	0	111.7	G133 Y134 S140 L141 S365 L369	G133-S137 VanDerWaalsContact O-CB 3.3Å; G133-S137 WeakPolarHBondContact O-CB 3.16Å; G133-S137 PolarHBondContact O-N 3.13Å; G133-S137 PolarHBondContact O-OG 3.24Å; G133-S137 VanDerWaalsContact O-OG 3.11Å; Y134-S137 PolarHBondContact O-N 2.99Å; S137-S140 WeakPolarHBondContact CA-OG 3.46Å; S137-S140 PolarHBondContact O-N 3.28Å; S137-S140 PolarHBondContact O-OG 3Å; S137-L141 VanDerWaalsContact O-CB 3.27Å; S137-L141 WeakPolarHBondContact O-CB 3.16Å; S137-L141 WeakPolarHBondContact O-CD1 3.39Å; S137-L141 WeakPolarHBondContact O-CG 3.37Å; S137-L141 PolarHBondContact O-N 3.45Å; S137-S365 WeakPolarHBondContact CB-O 3.27Å; S137-S365 PolarHBondContact OG-O 3.47Å; S137-L369 PolarHBondContact OG-N 3.27Å
138	L	96.3	Very high	93.7	Very high	36 Å²	36	39.3 Å²	39.3	19%	0.188	23%	0.227	C	C	.	.	H	α-helix	trans	-60.8	-48.7	179.2	-179.9	63.1	0	0	0	111.6	Y134 S135 V136 S140 L141 A142 I170 A173 I174 L177	Y134-L138 WeakPolarHBondContact O-CB 3.25Å; Y134-L138 PolarHBondContact O-N 3.47Å; S135-L138 PolarHBondContact O-N 3.04Å; V136-L138 PolarHBondContact O-N 3.35Å; L138-S140 PolarHBondContact O-N 2.92Å; L138-L141 PolarHBondContact O-N 2.73Å; L138-A142 VanDerWaalsContact O-CB 3.24Å; L138-A142 WeakPolarHBondContact O-CB 3.36Å; L138-A142 PolarHBondContact O-N 2.99Å; L138-I170 HydrophobicContact CD1-CB 4.23Å; L138-I170 HydrophobicContact CD1-CG1 4.18Å; L138-I170 HydrophobicContact CD1-CG2 3.79Å; L138-A173 HydrophobicContact CB-CB 4.32Å; L138-A173 HydrophobicContact CD1-CB 4.45Å; L138-I174 HydrophobicContact CD1-CD1 4.29Å; L138-I174 HydrophobicContact CD1-CG1 4Å; L138-I174 HydrophobicContact CD2-CG1 4.22Å; L138-L177 HydrophobicContact CD2-CD1 4.22Å
139	M	96.4	Very high	93.8	Very high	128 Å²	128	39.6 Å²	39.6	63%	0.631	23%	0.225	S	C	*	.	H	α-helix	trans	-63.1	-42.7	179.7	-68.4	-55.2	-63.9	0	0	112.5	S135 V136 T143	S135-M139 WeakPolarHBondContact O-CG 3.4Å; S135-M139 PolarHBondContact O-N 2.79Å; V136-M139 PolarHBondContact O-N 2.96Å; M139-T143 WeakPolarHBondContact O-CB 3.3Å; M139-T143 PolarHBondContact O-N 3.47Å; M139-T143 PolarHBondContact O-OG1 3.18Å
140	S	96.1	Very high	93.8	Very high	12 Å²	12	43.1 Å²	43.1	8%	0.084	24%	0.244	C	C	.	.	H	α-helix	trans	-67.1	-43.2	177.8	60.4	0	0	0	0	112.4	V136 S137 L138 T143 G144 L369	V136-S140 WeakPolarHBondContact O-CB 3.23Å; V136-S140 PolarHBondContact O-N 3.07Å; V136-S140 PolarHBondContact O-OG 3.01Å; S137-S140 WeakPolarHBondContact CA-OG 3.46Å; S137-S140 PolarHBondContact O-N 3.28Å; S137-S140 PolarHBondContact O-OG 3Å; L138-S140 PolarHBondContact O-N 2.92Å; S140-T143 PolarHBondContact O-N 3.11Å; S140-G144 PolarHBondContact O-N 3.16Å; S140-L369 WeakPolarHBondContact OG-CD1 3.36Å
141	L	96	Very high	93.7	Very high	1 Å²	1	44 Å²	44	1%	0.005	25%	0.248	C	C	.	.	H	α-helix	trans	-67.7	-40.5	177.7	-74.1	165.1	0	0	0	112.6	S137 L138 G144 S145 F166 F169 I170 A372	S137-L141 VanDerWaalsContact O-CB 3.27Å; S137-L141 WeakPolarHBondContact O-CB 3.16Å; S137-L141 WeakPolarHBondContact O-CD1 3.39Å; S137-L141 WeakPolarHBondContact O-CG 3.37Å; S137-L141 PolarHBondContact O-N 3.45Å; L138-L141 PolarHBondContact O-N 2.73Å; L141-G144 PolarHBondContact O-N 3.28Å; L141-S145 VanDerWaalsContact O-CB 3.27Å; L141-S145 WeakPolarHBondContact O-CB 3.36Å; L141-S145 PolarHBondContact O-N 3.29Å; L141-S145 PolarHBondContact O-OG 3.45Å; L141-F166 HydrophobicContact CD2-CB 4.04Å; L141-F166 HydrophobicContact CD2-CD1 3.77Å; L141-F166 HydrophobicContact CD2-CD2 4.32Å; L141-F166 HydrophobicContact CD2-CE1 4.35Å; L141-F166 HydrophobicContact CD2-CG 3.77Å; L141-F169 HydrophobicContact CD1-CB 3.39Å; L141-F169 HydrophobicContact CD1-CG 4.26Å; L141-I170 HydrophobicContact CB-CD1 4.11Å; L141-I170 HydrophobicContact CB-CG1 3.79Å; L141-I170 HydrophobicContact CD1-CG1 4.41Å; L141-A372 HydrophobicContact CD2-CB 3.89Å; L141-A372 HydrophobicContact CG-CB 4.17Å
142	A	95.9	Very high	93.4	Very high	34 Å²	34	52.5 Å²	52.5	28%	0.281	28%	0.276	S	S	.	.	H	α-helix	trans	-61.1	-48	174.8	0	0	0	0	0	110.3	L138 G144 S145 I146	L138-A142 VanDerWaalsContact O-CB 3.24Å; L138-A142 WeakPolarHBondContact O-CB 3.36Å; L138-A142 PolarHBondContact O-N 2.99Å; A142-G144 PolarHBondContact O-N 3.11Å; A142-S145 PolarHBondContact O-N 2.93Å; A142-I146 WeakPolarHBondContact O-CB 3.45Å; A142-I146 WeakPolarHBondContact O-CD1 3.33Å; A142-I146 WeakPolarHBondContact O-CG1 3.28Å; A142-I146 PolarHBondContact O-N 3.44Å
143	T	94.8	Very high	92.8	Very high	64 Å²	64	53.8 Å²	53.8	39%	0.393	28%	0.277	S	S	.	.	H	α-helix	trans	-60	-46.5	176.4	-56.3	0	0	0	0	111.4	M139 S140 I146 I147 F377	M139-T143 WeakPolarHBondContact O-CB 3.3Å; M139-T143 PolarHBondContact O-N 3.47Å; M139-T143 PolarHBondContact O-OG1 3.18Å; S140-T143 PolarHBondContact O-N 3.11Å; T143-I146 PolarHBondContact O-N 3.48Å; T143-I147 HydrophobicContact CG2-CD1 4.05Å; T143-I147 VanDerWaalsContact O-CG1 3.3Å; T143-I147 WeakPolarHBondContact O-CG1 3.5Å; T143-I147 PolarHBondContact O-N 3.19Å; T143-F377 HydrophobicContact CG2-CE1 4.23Å; T143-F377 HydrophobicContact CG2-CZ 4.21Å
144	G	93.8	Very high	92.2	Very high	0 Å²	0	54 Å²	54	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-63.3	-41.6	178.1	0	0	0	0	0	113.3	S140 L141 A142 I147 L148 C376	S140-G144 PolarHBondContact O-N 3.16Å; L141-G144 PolarHBondContact O-N 3.28Å; A142-G144 PolarHBondContact O-N 3.11Å; G144-I147 PolarHBondContact O-N 3.45Å; G144-L148 WeakPolarHBondContact O-CG 3.39Å; G144-L148 PolarHBondContact O-N 3.24Å; G144-C376 WeakPolarHBondContact CA-SG 3.47Å
145	S	93.7	Very high	91.7	Very high	14 Å²	14	56.6 Å²	56.6	10%	0.098	29%	0.29	C	S	.	.	H	α-helix	trans	-62.3	-44.9	175.5	-59.5	0	0	0	0	111.4	L141 A142 I147 L148 C149 F166	L141-S145 VanDerWaalsContact O-CB 3.27Å; L141-S145 WeakPolarHBondContact O-CB 3.36Å; L141-S145 PolarHBondContact O-N 3.29Å; L141-S145 PolarHBondContact O-OG 3.45Å; A142-S145 PolarHBondContact O-N 2.93Å; S145-I147 PolarHBondContact O-N 2.78Å; S145-L148 PolarHBondContact O-N 3.01Å; S145-C149 WeakPolarHBondContact O-CB 3.45Å; S145-C149 PolarHBondContact O-N 2.95Å; S145-C149 PolarHBondContact O-SG 3.34Å; S145-F166 WeakPolarHBondContact OG-CD2 3.34Å
146	I	93.2	Very high	91.2	Very high	99 Å²	99	57.1 Å²	57.1	51%	0.508	29%	0.293	S	S	.	.	H	α-helix	trans	-60	-46.3	176.5	-69.8	164.3	0	0	0	110.3	A142 T143 L148 C149 L150	A142-I146 WeakPolarHBondContact O-CB 3.45Å; A142-I146 WeakPolarHBondContact O-CD1 3.33Å; A142-I146 WeakPolarHBondContact O-CG1 3.28Å; A142-I146 PolarHBondContact O-N 3.44Å; T143-I146 PolarHBondContact O-N 3.48Å; I146-L148 PolarHBondContact O-N 2.8Å; I146-C149 PolarHBondContact O-N 3.06Å; I146-L150 HydrophobicContact CG2-CD1 3.61Å; I146-L150 HydrophobicContact CG2-CG 4.11Å; I146-L150 WeakPolarHBondContact O-CB 3.01Å; I146-L150 VanDerWaalsContact O-CG 3.22Å; I146-L150 WeakPolarHBondContact O-CG 3.45Å; I146-L150 PolarHBondContact O-N 2.99Å
147	I	92	Very high	90.7	Very high	29 Å²	29	56.1 Å²	56.1	15%	0.149	29%	0.287	C	S	.	.	H	α-helix	trans	-57.8	-51.3	177.8	-70.7	166.4	0	0	0	110.8	T143 G144 S145 C149 L150 F151 F377 V382	T143-I147 HydrophobicContact CG2-CD1 4.05Å; T143-I147 VanDerWaalsContact O-CG1 3.3Å; T143-I147 WeakPolarHBondContact O-CG1 3.5Å; T143-I147 PolarHBondContact O-N 3.19Å; G144-I147 PolarHBondContact O-N 3.45Å; S145-I147 PolarHBondContact O-N 2.78Å; I147-C149 VanDerWaalsContact C-N 3.3Å; I147-C149 PolarHBondContact O-N 2.68Å; I147-L150 PolarHBondContact O-N 3.43Å; I147-F151 HydrophobicContact CG2-CD2 4.01Å; I147-F151 HydrophobicContact CG2-CE2 4.05Å; I147-F151 WeakPolarHBondContact O-CD2 3.43Å; I147-F151 PolarHBondContact O-N 3.45Å; I147-F377 HydrophobicContact CD1-CD1 4.49Å; I147-F377 HydrophobicContact CD1-CE1 3.94Å; I147-V382 HydrophobicContact CG2-CG1 3.67Å
148	L	90.6	Very high	90.2	Very high	8 Å²	8	60.4 Å²	60.4	4%	0.042	30%	0.303	C	S	.	.	H	α-helix	trans	-62.7	-36.4	-179.8	-67.5	179.3	0	0	0	112.5	G144 S145 I146 L154 H155 F166 V382	G144-L148 WeakPolarHBondContact O-CG 3.39Å; G144-L148 PolarHBondContact O-N 3.24Å; S145-L148 PolarHBondContact O-N 3.01Å; I146-L148 PolarHBondContact O-N 2.8Å; L148-L154 HydrophobicContact CD2-CD1 4Å; L148-H155 PolarHBondContact O-NE2 3.37Å; L148-F166 HydrophobicContact CD1-CD2 4.37Å; L148-F166 HydrophobicContact CD1-CE2 3.77Å; L148-F166 HydrophobicContact CD1-CZ 4.37Å; L148-V382 HydrophobicContact CD2-CG2 4.09Å
149	C	91	Very high	89.9	Confident	63 Å²	63	59.1 Å²	59.1	43%	0.426	30%	0.296	S	S	.	.	H	α-helix	trans	-69.2	-41.4	177.2	-75.1	0	0	0	0	112.9	S145 I146 I147 H155	S145-C149 WeakPolarHBondContact O-CB 3.45Å; S145-C149 PolarHBondContact O-N 2.95Å; S145-C149 PolarHBondContact O-SG 3.34Å; I146-C149 PolarHBondContact O-N 3.06Å; I147-C149 VanDerWaalsContact C-N 3.3Å; I147-C149 PolarHBondContact O-N 2.68Å; C149-H155 PolarHBondContact O-NE2 2.88Å; C149-H155 VanDerWaalsContact O-NE2 3.14Å
150	L	89.5	Confident	89.6	Confident	133 Å²	133	57.6 Å²	57.6	70%	0.696	28%	0.284	S	S	*	.	H	α-helix	trans	-70.3	-36.2	-175.2	-73	175.1	0	0	0	113.4	I146 I147 R152	I146-L150 HydrophobicContact CG2-CD1 3.61Å; I146-L150 HydrophobicContact CG2-CG 4.11Å; I146-L150 WeakPolarHBondContact O-CB 3.01Å; I146-L150 VanDerWaalsContact O-CG 3.22Å; I146-L150 WeakPolarHBondContact O-CG 3.45Å; I146-L150 PolarHBondContact O-N 2.99Å; I147-L150 PolarHBondContact O-N 3.43Å; L150-R152 PolarHBondContact O-N 3Å
151	F	87.9	Confident	89.4	Confident	35 Å²	35	57 Å²	57	15%	0.154	28%	0.28	C	S	.	.			trans	-90.1	95.8	-178.5	-66.3	-72.6	0	0	0	111.2	I147 K153 L154 K389	I147-F151 HydrophobicContact CG2-CD2 4.01Å; I147-F151 HydrophobicContact CG2-CE2 4.05Å; I147-F151 WeakPolarHBondContact O-CD2 3.43Å; I147-F151 PolarHBondContact O-N 3.45Å; F151-K153 PolarHBondContact O-N 2.96Å; F151-L154 HydrophobicContact CB-CB 4.45Å; F151-L154 HydrophobicContact CB-CD1 3.76Å; F151-L154 HydrophobicContact CB-CG 3.92Å; F151-L154 HydrophobicContact CD2-CD1 4.28Å; F151-L154 HydrophobicContact CG-CD1 4.37Å; F151-L154 WeakPolarHBondContact O-CB 3.21Å; F151-L154 PolarHBondContact O-N 2.94Å; F151-K389 HydrophobicContact CE1-CB 3.98Å; F151-K389 HydrophobicContact CE1-CD 4.4Å; F151-K389 HydrophobicContact CE1-CG 4.11Å; F151-K389 HydrophobicContact CZ-CB 4.22Å; F151-K389 HydrophobicContact CZ-CG 4.37Å
152	R	85.1	Confident	89.2	Confident	220 Å²	220	57.2 Å²	57.2	83%	0.83	28%	0.281	S	S	*	.	G	3₁₀ helix	trans	-50.9	-30.1	176.9	-174.8	175	174.5	167.7	-1.6	114.2	L150 L154 H155	L150-R152 PolarHBondContact O-N 3Å; R152-L154 PolarHBondContact O-N 3.37Å; R152-H155 WeakPolarHBondContact O-CB 3.31Å; R152-H155 PolarHBondContact O-N 2.9Å; R152-H155 VanDerWaalsContact O-N 3.16Å
153	K	81.7	Confident	89	Confident	133 Å²	133	57.9 Å²	57.9	58%	0.578	28%	0.28	S	S	*	.	G	3₁₀ helix	trans	-64.6	-24.3	176.7	-76.1	-162.4	175.8	-171.4	0	113.9	F151 H155 E385 R388	F151-K153 PolarHBondContact O-N 2.96Å; K153-H155 VanDerWaalsContact C-N 3.28Å; K153-E385 VanDerWaalsContact CD-OE1 3.3Å; K153-E385 WeakPolarHBondContact CD-OE1 3.3Å; K153-E385 IonicContact NZ-OE1 3.45Å; K153-R388 VanDerWaalsContact CE-NH2 3.29Å; K153-R388 VanDerWaalsContact NZ-CZ 3.32Å
154	L	81.8	Confident	89	Confident	5 Å²	5	55.9 Å²	55.9	3%	0.026	27%	0.267	C	S	.	.	G	3₁₀ helix	trans	-86.5	4.5	177.8	-58.8	177.5	0	0	0	112	L148 F151 R152 C156 N159 E381 V382 E385	L148-L154 HydrophobicContact CD2-CD1 4Å; F151-L154 HydrophobicContact CB-CB 4.45Å; F151-L154 HydrophobicContact CB-CD1 3.76Å; F151-L154 HydrophobicContact CB-CG 3.92Å; F151-L154 HydrophobicContact CD2-CD1 4.28Å; F151-L154 HydrophobicContact CG-CD1 4.37Å; F151-L154 WeakPolarHBondContact O-CB 3.21Å; F151-L154 PolarHBondContact O-N 2.94Å; R152-L154 PolarHBondContact O-N 3.37Å; L154-C156 VanDerWaalsContact C-N 3.27Å; L154-C156 PolarHBondContact O-N 3.44Å; L154-N159 VanDerWaalsContact O-CB 3.24Å; L154-N159 WeakPolarHBondContact O-CB 3.43Å; L154-N159 PolarHBondContact O-ND2 2.88Å; L154-E381 HydrophobicContact CD2-CB 4.14Å; L154-V382 HydrophobicContact CD1-CG2 3.98Å; L154-E385 HydrophobicContact CD2-CG 4.29Å
155	H	83.5	Confident	89	Confident	67 Å²	67	55.9 Å²	55.9	31%	0.31	27%	0.267	S	S	.	.			trans	-79.6	74.4	-178.3	-72.6	-158.3	0	0	0	111.7	L148 C149 R152 K153 Y160	L148-H155 PolarHBondContact O-NE2 3.37Å; C149-H155 PolarHBondContact O-NE2 2.88Å; C149-H155 VanDerWaalsContact O-NE2 3.14Å; R152-H155 WeakPolarHBondContact O-CB 3.31Å; R152-H155 PolarHBondContact O-N 2.9Å; R152-H155 VanDerWaalsContact O-N 3.16Å; K153-H155 VanDerWaalsContact C-N 3.28Å; H155-Y160 HydrophobicContact CB-CE2 4.39Å
156	C	84.2	Confident	89.1	Confident	56 Å²	56	55.2 Å²	55.2	38%	0.378	26%	0.262	S	S	.	.			trans	-108.7	156.4	174.7	-66.3	0	0	0	0	110.6	L154 R158 N159 Y160	L154-C156 VanDerWaalsContact C-N 3.27Å; L154-C156 PolarHBondContact O-N 3.44Å; C156-R158 PolarHBondContact O-N 2.81Å; C156-R158 VanDerWaalsContact O-N 3.16Å; C156-N159 PolarHBondContact O-N 3.27Å; C156-Y160 WeakPolarHBondContact O-CD2 2.99Å; C156-Y160 PolarHBondContact O-N 3.4Å
157	T	84.6	Confident	89.2	Confident	38 Å²	38	51.9 Å²	51.9	23%	0.233	25%	0.245	C	C	.	.	H	α-helix	trans	-51.1	-41.2	176.4	-57.6	0	0	0	0	112.4	N159 Y160 I161 F241	T157-N159 PolarHBondContact O-N 3.42Å; T157-Y160 WeakPolarHBondContact O-CB 3.49Å; T157-Y160 PolarHBondContact O-N 2.9Å; T157-I161 WeakPolarHBondContact O-CG1 3.34Å; T157-I161 PolarHBondContact O-N 3.28Å; T157-I161 VanDerWaalsContact O-N 3.12Å; T157-F241 HydrophobicContact CG2-CD2 3.84Å; T157-F241 HydrophobicContact CG2-CE2 4.43Å
158	R	86.6	Confident	89.4	Confident	94 Å²	94	50.6 Å²	50.6	36%	0.355	24%	0.238	S	C	.	.	H	α-helix	trans	-56.4	-49.8	174.5	-179.2	-174.7	-55.9	113.1	1.7	112.5	C156 Y160 I161 H162 Y226	C156-R158 PolarHBondContact O-N 2.81Å; C156-R158 VanDerWaalsContact O-N 3.16Å; R158-Y160 VanDerWaalsContact C-N 3.26Å; R158-Y160 PolarHBondContact O-N 3.44Å; R158-I161 WeakPolarHBondContact O-CB 3.42Å; R158-I161 PolarHBondContact O-N 3.48Å; R158-I161 VanDerWaalsContact O-N 3.08Å; R158-H162 WeakPolarHBondContact CG-NE2 3.45Å; R158-H162 PolarHBondContact O-N 3.49Å; R158-Y226 HydrophobicContact CB-CE1 4.16Å; R158-Y226 HydrophobicContact CG-CE1 4.14Å
159	N	89.5	Confident	89.6	Confident	8 Å²	8	50.7 Å²	50.7	4%	0.043	24%	0.238	C	C	.	.	H	α-helix	trans	-70.3	-25.1	-178.2	-67.7	-14.8	0	0	0	112.1	L154 C156 T157 L163	L154-N159 VanDerWaalsContact O-CB 3.24Å; L154-N159 WeakPolarHBondContact O-CB 3.43Å; L154-N159 PolarHBondContact O-ND2 2.88Å; C156-N159 PolarHBondContact O-N 3.27Å; T157-N159 PolarHBondContact O-N 3.42Å; N159-L163 VanDerWaalsContact O-CB 3.3Å; N159-L163 WeakPolarHBondContact O-CB 3.31Å; N159-L163 PolarHBondContact O-N 3.3Å
160	Y	90.3	Very high	89.8	Confident	96 Å²	96	48.9 Å²	48.9	38%	0.376	22%	0.224	S	C	.	.	H	α-helix	trans	-68	-38.9	168.2	-72	-65.3	0	0	0	112.7	H155 C156 T157 R158 L163 N164	H155-Y160 HydrophobicContact CB-CE2 4.39Å; C156-Y160 WeakPolarHBondContact O-CD2 2.99Å; C156-Y160 PolarHBondContact O-N 3.4Å; T157-Y160 WeakPolarHBondContact O-CB 3.49Å; T157-Y160 PolarHBondContact O-N 2.9Å; R158-Y160 VanDerWaalsContact C-N 3.26Å; R158-Y160 PolarHBondContact O-N 3.44Å; Y160-L163 PolarHBondContact O-N 3.39Å; Y160-N164 PolarHBondContact O-N 3.37Å; Y160-N164 VanDerWaalsContact O-N 3.1Å; Y160-N164 PolarHBondContact O-ND2 2.97Å
161	I	90.9	Very high	90.1	Very high	0 Å²	0	43 Å²	43	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-63.9	-47.6	173.2	-60.9	-65.7	0	0	0	109.7	T157 R158 L163 N164 L165 W219 V222 E223 F241 Y244	T157-I161 WeakPolarHBondContact O-CG1 3.34Å; T157-I161 PolarHBondContact O-N 3.28Å; T157-I161 VanDerWaalsContact O-N 3.12Å; R158-I161 WeakPolarHBondContact O-CB 3.42Å; R158-I161 PolarHBondContact O-N 3.48Å; R158-I161 VanDerWaalsContact O-N 3.08Å; I161-L163 VanDerWaalsContact C-N 3.31Å; I161-L163 PolarHBondContact O-N 3.44Å; I161-N164 PolarHBondContact O-N 3.13Å; I161-L165 PolarHBondContact O-N 3.19Å; I161-W219 HydrophobicContact CD1-CZ3 4.28Å; I161-W219 HydrophobicContact CG2-CZ3 4.36Å; I161-V222 HydrophobicContact CD1-CG1 4.32Å; I161-V222 HydrophobicContact CG2-CG1 4.35Å; I161-E223 WeakPolarHBondContact CG2-OE2 3.42Å; I161-F241 HydrophobicContact CD1-CD2 3.83Å; I161-F241 HydrophobicContact CD1-CE2 3.61Å; I161-F241 HydrophobicContact CG1-CD2 4.48Å; I161-F241 HydrophobicContact CG1-CE2 4.2Å; I161-Y244 HydrophobicContact CD1-CD2 4.47Å
162	H	91.8	Very high	90.4	Very high	6 Å²	6	42.2 Å²	42.2	3%	0.028	19%	0.189	C	C	.	.	H	α-helix	trans	-60.1	-37.6	175.8	-60.1	-30.8	0	0	0	112.9	R158 L165 F166 E223 Y375	R158-H162 WeakPolarHBondContact CG-NE2 3.45Å; R158-H162 PolarHBondContact O-N 3.49Å; H162-L165 WeakPolarHBondContact O-CB 3.34Å; H162-L165 PolarHBondContact O-N 2.85Å; H162-F166 HydrophobicContact CB-CE1 4.48Å; H162-F166 WeakPolarHBondContact O-CB 3.34Å; H162-F166 WeakPolarHBondContact O-CD1 3.38Å; H162-F166 VanDerWaalsContact O-CG 3.25Å; H162-F166 WeakPolarHBondContact O-CG 3.46Å; H162-F166 PolarHBondContact O-N 3.31Å; H162-E223 IonicContact CE1-OE1 2.89Å; H162-E223 PolarHBondContact CE1-OE1 3.31Å; H162-E223 IonicContact CE1-OE2 3.82Å; H162-E223 IonicContact ND1-OE1 3.38Å; H162-E223 PolarHBondContact ND1-OE1 2.87Å; H162-E223 VanDerWaalsContact ND1-OE1 3.11Å; H162-E223 IonicContact ND1-OE2 3.49Å; H162-E223 PolarHBondContact ND1-OE2 3.48Å; H162-E223 VanDerWaalsContact ND1-OE2 3.09Å; H162-Y375 AromaticContact CE1-CD1 3.52Å; H162-Y375 AromaticContact CE1-CE1 3.41Å; H162-Y375 VanDerWaalsContact CE1-CE1 3.41Å; H162-Y375 WeakPolarHBondContact CE1-CE1 3.41Å; H162-Y375 AromaticContact CE1-CZ 3.8Å; H162-Y375 AromaticContact NE2-CD1 3.55Å; H162-Y375 AromaticContact NE2-CE1 3.81Å
163	L	93.1	Very high	90.9	Very high	48 Å²	48	31.8 Å²	31.8	25%	0.251	15%	0.15	S	C	.	.	H	α-helix	trans	-65.8	-40.5	176.9	-174.7	68.8	0	0	0	111.9	N159 Y160 I161 L165 F166 L167	N159-L163 VanDerWaalsContact O-CB 3.3Å; N159-L163 WeakPolarHBondContact O-CB 3.31Å; N159-L163 PolarHBondContact O-N 3.3Å; Y160-L163 PolarHBondContact O-N 3.39Å; I161-L163 VanDerWaalsContact C-N 3.31Å; I161-L163 PolarHBondContact O-N 3.44Å; L163-L165 VanDerWaalsContact C-N 3.35Å; L163-F166 PolarHBondContact O-N 2.95Å; L163-L167 WeakPolarHBondContact O-CB 3.06Å; L163-L167 PolarHBondContact O-N 3.49Å
164	N	94.6	Very high	91.5	Very high	22 Å²	22	28.3 Å²	28.3	12%	0.118	14%	0.138	C	C	.	.	H	α-helix	trans	-67.2	-38.3	174.1	-80.5	-88	0	0	0	111.5	Y160 I161 L167 S168 W219 W249	Y160-N164 PolarHBondContact O-N 3.37Å; Y160-N164 VanDerWaalsContact O-N 3.1Å; Y160-N164 PolarHBondContact O-ND2 2.97Å; I161-N164 PolarHBondContact O-N 3.13Å; N164-L167 PolarHBondContact O-N 3.07Å; N164-S168 PolarHBondContact O-N 3.01Å; N164-W219 HydrophobicContact CB-CD2 3.88Å; N164-W219 HydrophobicContact CB-CE3 3.64Å; N164-W219 HydrophobicContact CB-CH2 3.24Å; N164-W219 HydrophobicContact CB-CZ2 3.5Å; N164-W219 VanDerWaalsContact CB-CZ2 3.5Å; N164-W219 HydrophobicContact CB-CZ3 3.3Å; N164-W219 VanDerWaalsContact CG-CH2 3.49Å; N164-W249 PolarHBondContact OD1-NE1 3.33Å
165	L	93.2	Very high	92	Very high	0 Å²	0	28.3 Å²	28.3	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-59.8	-47.5	172.4	-175.2	65.7	0	0	0	111.1	I161 H162 L163 L167 S168 F169 W219 L220 E223 L336 V371 Y375	I161-L165 PolarHBondContact O-N 3.19Å; H162-L165 WeakPolarHBondContact O-CB 3.34Å; H162-L165 PolarHBondContact O-N 2.85Å; L163-L165 VanDerWaalsContact C-N 3.35Å; L165-L167 VanDerWaalsContact C-N 3.32Å; L165-L167 PolarHBondContact O-N 3.47Å; L165-S168 WeakPolarHBondContact O-CB 3.32Å; L165-S168 PolarHBondContact O-N 3.46Å; L165-S168 VanDerWaalsContact O-N 3.16Å; L165-S168 PolarHBondContact O-OG 3.48Å; L165-F169 HydrophobicContact CD1-CD2 4.37Å; L165-F169 HydrophobicContact CD1-CE2 3.98Å; L165-F169 HydrophobicContact CG-CD2 4.23Å; L165-F169 HydrophobicContact CG-CE2 4.06Å; L165-F169 WeakPolarHBondContact O-CD2 3.3Å; L165-F169 PolarHBondContact O-N 3.34Å; L165-F169 VanDerWaalsContact O-N 3.13Å; L165-W219 HydrophobicContact CD1-CB 3.73Å; L165-L220 HydrophobicContact CD1-CD2 3.97Å; L165-L220 HydrophobicContact CD1-CG 4.28Å; L165-E223 HydrophobicContact CD2-CB 4.36Å; L165-E223 HydrophobicContact CD2-CG 4.07Å; L165-L336 HydrophobicContact CD2-CD1 4.49Å; L165-V371 HydrophobicContact CD2-CG1 3.97Å; L165-Y375 HydrophobicContact CD2-CE2 4.33Å
166	F	95.5	Very high	92.3	Very high	0 Å²	0	25.8 Å²	25.8	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-61.2	-43.3	177.1	-70.3	8.7	0	0	0	110.8	L141 S145 L148 H162 L163 S168 F169 I170 V371 Y375 C376	L141-F166 HydrophobicContact CD2-CB 4.04Å; L141-F166 HydrophobicContact CD2-CD1 3.77Å; L141-F166 HydrophobicContact CD2-CD2 4.32Å; L141-F166 HydrophobicContact CD2-CE1 4.35Å; L141-F166 HydrophobicContact CD2-CG 3.77Å; S145-F166 WeakPolarHBondContact OG-CD2 3.34Å; L148-F166 HydrophobicContact CD1-CD2 4.37Å; L148-F166 HydrophobicContact CD1-CE2 3.77Å; L148-F166 HydrophobicContact CD1-CZ 4.37Å; H162-F166 HydrophobicContact CB-CE1 4.48Å; H162-F166 WeakPolarHBondContact O-CB 3.34Å; H162-F166 WeakPolarHBondContact O-CD1 3.38Å; H162-F166 VanDerWaalsContact O-CG 3.25Å; H162-F166 WeakPolarHBondContact O-CG 3.46Å; H162-F166 PolarHBondContact O-N 3.31Å; L163-F166 PolarHBondContact O-N 2.95Å; F166-S168 VanDerWaalsContact C-N 3.31Å; F166-S168 PolarHBondContact O-N 2.91Å; F166-F169 PolarHBondContact O-N 2.93Å; F166-I170 WeakPolarHBondContact O-CB 3.23Å; F166-I170 VanDerWaalsContact O-CG1 3.26Å; F166-I170 WeakPolarHBondContact O-CG1 3.48Å; F166-I170 PolarHBondContact O-N 2.98Å; F166-V371 HydrophobicContact CD1-CG1 4.04Å; F166-V371 HydrophobicContact CE1-CG1 3.71Å; F166-Y375 HydrophobicContact CE1-CD2 4.43Å; F166-C376 HydrophobicContact CE2-CB 4.22Å; F166-C376 HydrophobicContact CZ-CB 4.28Å
167	L	95.6	Very high	92.6	Very high	29 Å²	29	25.1 Å²	25.1	15%	0.152	12%	0.12	C	C	.	.	H	α-helix	trans	-59.4	-41.7	175.4	-177.9	60.6	0	0	0	111.5	P6 L9 L163 N164 L165 F169 I170 L171 W249	P6-L167 HydrophobicContact CG-CD2 3.91Å; L9-L167 HydrophobicContact CD1-CD1 4.08Å; L9-L167 HydrophobicContact CD1-CD2 3.83Å; L9-L167 HydrophobicContact CD2-CD1 4.41Å; L9-L167 HydrophobicContact CG-CD1 4.49Å; L163-L167 WeakPolarHBondContact O-CB 3.06Å; L163-L167 PolarHBondContact O-N 3.49Å; N164-L167 PolarHBondContact O-N 3.07Å; L165-L167 VanDerWaalsContact C-N 3.32Å; L165-L167 PolarHBondContact O-N 3.47Å; L167-F169 VanDerWaalsContact C-N 3.35Å; L167-F169 PolarHBondContact O-N 2.96Å; L167-I170 PolarHBondContact O-N 2.85Å; L167-L171 HydrophobicContact CD1-CD1 4.4Å; L167-L171 HydrophobicContact CD1-CG 4.2Å; L167-L171 HydrophobicContact CG-CD1 4.2Å; L167-L171 HydrophobicContact CG-CG 4.43Å; L167-L171 WeakPolarHBondContact O-CB 3.27Å; L167-L171 VanDerWaalsContact O-CG 3.31Å; L167-L171 WeakPolarHBondContact O-CG 3.27Å; L167-L171 PolarHBondContact O-N 3.38Å; L167-W249 HydrophobicContact CB-CZ2 4.48Å; L167-W249 HydrophobicContact CD2-CH2 4.37Å; L167-W249 HydrophobicContact CD2-CZ2 3.94Å; L167-W249 HydrophobicContact CG-CH2 4.24Å; L167-W249 HydrophobicContact CG-CZ2 4.19Å
168	S	95.6	Very high	92.6	Very high	1 Å²	1	26.2 Å²	26.2	1%	0.007	13%	0.126	C	C	.	.	H	α-helix	trans	-61.4	-40.7	176.3	82.3	0	0	0	0	112.7	N164 L165 F166 R172 N216	N164-S168 PolarHBondContact O-N 3.01Å; L165-S168 WeakPolarHBondContact O-CB 3.32Å; L165-S168 PolarHBondContact O-N 3.46Å; L165-S168 VanDerWaalsContact O-N 3.16Å; L165-S168 PolarHBondContact O-OG 3.48Å; F166-S168 VanDerWaalsContact C-N 3.31Å; F166-S168 PolarHBondContact O-N 2.91Å; S168-R172 WeakPolarHBondContact O-CB 3.03Å; S168-R172 PolarHBondContact O-N 3.21Å; S168-N216 PolarHBondContact OG-ND2 3.09Å
169	F	95.2	Very high	92.4	Very high	10 Å²	10	23.5 Å²	23.5	4%	0.044	12%	0.117	C	C	.	.	H	α-helix	trans	-70.4	-38.6	176	-83	-74.6	0	0	0	112.4	L141 L165 F166 L167 R172 A173 N216 L220 Q367 V371	L141-F169 HydrophobicContact CD1-CB 3.39Å; L141-F169 HydrophobicContact CD1-CG 4.26Å; L165-F169 HydrophobicContact CD1-CD2 4.37Å; L165-F169 HydrophobicContact CD1-CE2 3.98Å; L165-F169 HydrophobicContact CG-CD2 4.23Å; L165-F169 HydrophobicContact CG-CE2 4.06Å; L165-F169 WeakPolarHBondContact O-CD2 3.3Å; L165-F169 PolarHBondContact O-N 3.34Å; L165-F169 VanDerWaalsContact O-N 3.13Å; F166-F169 PolarHBondContact O-N 2.93Å; L167-F169 VanDerWaalsContact C-N 3.35Å; L167-F169 PolarHBondContact O-N 2.96Å; F169-R172 PolarHBondContact O-N 3.34Å; F169-A173 WeakPolarHBondContact O-CB 3.45Å; F169-A173 PolarHBondContact O-N 2.94Å; F169-N216 VanDerWaalsContact CD1-ND2 3.28Å; F169-N216 WeakPolarHBondContact CD1-ND2 3.46Å; F169-N216 WeakPolarHBondContact CD2-ND2 3.37Å; F169-N216 VanDerWaalsContact CE1-ND2 3.34Å; F169-N216 WeakPolarHBondContact CE1-ND2 3.4Å; F169-N216 VanDerWaalsContact CG-ND2 3.33Å; F169-N216 WeakPolarHBondContact CG-ND2 3.26Å; F169-N216 WeakPolarHBondContact CZ-ND2 3.3Å; F169-L220 HydrophobicContact CE2-CD2 3.94Å; F169-L220 HydrophobicContact CZ-CD1 4.38Å; F169-L220 HydrophobicContact CZ-CD2 3.84Å; F169-L220 HydrophobicContact CZ-CG 4.38Å; F169-Q367 HydrophobicContact CE1-CB 4.12Å; F169-Q367 HydrophobicContact CE1-CG 3.96Å; F169-Q367 HydrophobicContact CZ-CG 3.94Å; F169-V371 HydrophobicContact CE2-CB 4.45Å; F169-V371 HydrophobicContact CE2-CG1 4.37Å; F169-V371 HydrophobicContact CE2-CG2 3.81Å; F169-V371 HydrophobicContact CZ-CG2 3.99Å
170	I	96.2	Very high	92	Very high	26 Å²	26	23.5 Å²	23.5	13%	0.133	12%	0.117	C	C	.	.	H	α-helix	trans	-60.6	-49.3	175.1	-72.2	167.2	0	0	0	109.8	L138 L141 F166 L167 R172 A173 I174	L138-I170 HydrophobicContact CD1-CB 4.23Å; L138-I170 HydrophobicContact CD1-CG1 4.18Å; L138-I170 HydrophobicContact CD1-CG2 3.79Å; L141-I170 HydrophobicContact CB-CD1 4.11Å; L141-I170 HydrophobicContact CB-CG1 3.79Å; L141-I170 HydrophobicContact CD1-CG1 4.41Å; F166-I170 WeakPolarHBondContact O-CB 3.23Å; F166-I170 VanDerWaalsContact O-CG1 3.26Å; F166-I170 WeakPolarHBondContact O-CG1 3.48Å; F166-I170 PolarHBondContact O-N 2.98Å; L167-I170 PolarHBondContact O-N 2.85Å; I170-R172 PolarHBondContact O-N 2.84Å; I170-A173 PolarHBondContact O-N 3.33Å; I170-I174 HydrophobicContact CG2-CD1 3.68Å; I170-I174 HydrophobicContact CG2-CG1 4.45Å; I170-I174 WeakPolarHBondContact O-CB 3.25Å; I170-I174 VanDerWaalsContact O-CG1 3.3Å; I170-I174 WeakPolarHBondContact O-CG1 3.15Å; I170-I174 PolarHBondContact O-N 2.84Å
171	L	95.5	Very high	91.4	Very high	8 Å²	8	24.4 Å²	24.4	4%	0.042	13%	0.128	C	C	.	.	H	α-helix	trans	-61.4	-44.2	177.5	-69.8	176.1	0	0	0	111.3	L167 A173 I174 S175 F208 C212 W249	L167-L171 HydrophobicContact CD1-CD1 4.4Å; L167-L171 HydrophobicContact CD1-CG 4.2Å; L167-L171 HydrophobicContact CG-CD1 4.2Å; L167-L171 HydrophobicContact CG-CG 4.43Å; L167-L171 WeakPolarHBondContact O-CB 3.27Å; L167-L171 VanDerWaalsContact O-CG 3.31Å; L167-L171 WeakPolarHBondContact O-CG 3.27Å; L167-L171 PolarHBondContact O-N 3.38Å; L171-A173 PolarHBondContact O-N 2.97Å; L171-I174 PolarHBondContact O-N 2.83Å; L171-S175 WeakPolarHBondContact O-CB 3.25Å; L171-S175 PolarHBondContact O-N 2.86Å; L171-S175 PolarHBondContact O-OG 3.42Å; L171-F208 HydrophobicContact CD2-CZ 4.4Å; L171-C212 HydrophobicContact CB-CB 4.41Å; L171-W249 HydrophobicContact CD1-CH2 3.74Å; L171-W249 HydrophobicContact CD1-CZ3 3.94Å
172	R	94.9	Very high	90.3	Very high	19 Å²	19	25.2 Å²	25.2	7%	0.072	13%	0.133	C	C	.	.	H	α-helix	trans	-58.9	-47.1	174.8	-179.5	178.6	172.1	179.8	-0.2	112.1	S168 F169 I170 S175 V176 C212 I213 N216 Y341	S168-R172 WeakPolarHBondContact O-CB 3.03Å; S168-R172 PolarHBondContact O-N 3.21Å; F169-R172 PolarHBondContact O-N 3.34Å; I170-R172 PolarHBondContact O-N 2.84Å; R172-S175 PolarHBondContact O-N 2.73Å; R172-V176 VanDerWaalsContact O-CG2 3.3Å; R172-V176 WeakPolarHBondContact O-CG2 3.39Å; R172-V176 PolarHBondContact O-N 3Å; R172-C212 HydrophobicContact CB-CB 4.47Å; R172-I213 HydrophobicContact CG-CG1 4.45Å; R172-N216 HydrophobicContact CB-CB 4.47Å; R172-N216 PolarHBondContact NH1-OD1 3.35Å; R172-Y341 PolarHBondContact NH1-OH 3.45Å; R172-Y341 PolarHBondContact NH2-OH 3.43Å
173	A	94.4	Very high	89	Confident	1 Å²	1	25.6 Å²	25.6	1%	0.008	14%	0.135	C	C	.	.	H	α-helix	trans	-63.2	-47	179.7	0	0	0	0	0	111.6	Y134 L138 F169 I170 L171 S175 V176 L177	Y134-A173 HydrophobicContact CD1-CB 3.86Å; Y134-A173 HydrophobicContact CG-CB 4.4Å; L138-A173 HydrophobicContact CB-CB 4.32Å; L138-A173 HydrophobicContact CD1-CB 4.45Å; F169-A173 WeakPolarHBondContact O-CB 3.45Å; F169-A173 PolarHBondContact O-N 2.94Å; I170-A173 PolarHBondContact O-N 3.33Å; L171-A173 PolarHBondContact O-N 2.97Å; A173-S175 PolarHBondContact O-N 3.41Å; A173-V176 PolarHBondContact O-N 3.27Å; A173-L177 WeakPolarHBondContact O-CB 3.45Å; A173-L177 VanDerWaalsContact O-CG 3.24Å; A173-L177 WeakPolarHBondContact O-CG 3.28Å; A173-L177 PolarHBondContact O-N 3.25Å
174	I	94.1	Very high	87.7	Confident	61 Å²	61	28.4 Å²	28.4	31%	0.313	14%	0.143	S	C	.	.	H	α-helix	trans	-60.4	-47.2	176.8	-67.6	169.1	0	0	0	110.2	L138 I170 L171 V176 L177 V178	L138-I174 HydrophobicContact CD1-CD1 4.29Å; L138-I174 HydrophobicContact CD1-CG1 4Å; L138-I174 HydrophobicContact CD2-CG1 4.22Å; I170-I174 HydrophobicContact CG2-CD1 3.68Å; I170-I174 HydrophobicContact CG2-CG1 4.45Å; I170-I174 WeakPolarHBondContact O-CB 3.25Å; I170-I174 VanDerWaalsContact O-CG1 3.3Å; I170-I174 WeakPolarHBondContact O-CG1 3.15Å; I170-I174 PolarHBondContact O-N 2.84Å; L171-I174 PolarHBondContact O-N 2.83Å; I174-V176 VanDerWaalsContact C-N 3.34Å; I174-V176 PolarHBondContact O-N 2.96Å; I174-L177 PolarHBondContact O-N 2.82Å; I174-V178 HydrophobicContact CG2-CG2 4.05Å; I174-V178 WeakPolarHBondContact O-CB 3.41Å; I174-V178 VanDerWaalsContact O-CG2 3.23Å; I174-V178 WeakPolarHBondContact O-CG2 3.36Å; I174-V178 PolarHBondContact O-N 3.49Å
175	S	92	Very high	85.9	Confident	4 Å²	4	29.6 Å²	29.6	3%	0.028	15%	0.153	C	C	.	.	H	α-helix	trans	-63	-38.3	-179.5	-62.4	0	0	0	0	113.1	L171 R172 A173 K179 F208 C212	L171-S175 WeakPolarHBondContact O-CB 3.25Å; L171-S175 PolarHBondContact O-N 2.86Å; L171-S175 PolarHBondContact O-OG 3.42Å; R172-S175 PolarHBondContact O-N 2.73Å; A173-S175 PolarHBondContact O-N 3.41Å; S175-K179 VanDerWaalsContact O-CB 3.27Å; S175-K179 WeakPolarHBondContact O-CB 3.26Å; S175-K179 PolarHBondContact O-N 3.4Å; S175-F208 WeakPolarHBondContact OG-CD1 3.29Å; S175-F208 WeakPolarHBondContact OG-CE1 3.47Å; S175-C212 PolarHBondContact OG-SG 3.44Å
176	V	89.5	Confident	83.8	Confident	14 Å²	14	35.5 Å²	35.5	9%	0.085	19%	0.194	C	C	.	.	H	α-helix	trans	-66.8	-47.3	175.2	172.9	0	0	0	0	110.5	Y130 Y134 R172 A173 I174 V178 K179 D180 L209	Y130-V176 HydrophobicContact CD2-CG1 4.49Å; Y130-V176 HydrophobicContact CE2-CG1 4.23Å; Y134-V176 HydrophobicContact CD2-CB 4.32Å; Y134-V176 HydrophobicContact CD2-CG1 3.83Å; Y134-V176 HydrophobicContact CE2-CB 4.17Å; Y134-V176 HydrophobicContact CE2-CG1 3.66Å; Y134-V176 HydrophobicContact CE2-CG2 4.23Å; R172-V176 VanDerWaalsContact O-CG2 3.3Å; R172-V176 WeakPolarHBondContact O-CG2 3.39Å; R172-V176 PolarHBondContact O-N 3Å; A173-V176 PolarHBondContact O-N 3.27Å; I174-V176 VanDerWaalsContact C-N 3.34Å; I174-V176 PolarHBondContact O-N 2.96Å; V176-V178 VanDerWaalsContact C-N 3.35Å; V176-V178 PolarHBondContact O-N 3.42Å; V176-K179 WeakPolarHBondContact O-CB 3.45Å; V176-K179 PolarHBondContact O-N 2.93Å; V176-D180 VanDerWaalsContact O-CG 3.29Å; V176-D180 PolarHBondContact O-N 3.05Å; V176-D180 VanDerWaalsContact O-OD2 3.06Å; V176-L209 HydrophobicContact CG2-CD1 3.78Å
177	L	90.5	Very high	81.3	Confident	43 Å²	43	40 Å²	40	23%	0.225	23%	0.226	C	C	.	.	H	α-helix	trans	-62.2	-41.9	178.6	-68.1	172.5	0	0	0	112	T131 L138 A173 I174 D180 D181	T131-L177 HydrophobicContact CG2-CD2 3.88Å; L138-L177 HydrophobicContact CD2-CD1 4.22Å; A173-L177 WeakPolarHBondContact O-CB 3.45Å; A173-L177 VanDerWaalsContact O-CG 3.24Å; A173-L177 WeakPolarHBondContact O-CG 3.28Å; A173-L177 PolarHBondContact O-N 3.25Å; I174-L177 PolarHBondContact O-N 2.82Å; L177-D180 PolarHBondContact O-N 3.26Å; L177-D181 WeakPolarHBondContact O-CB 3.19Å; L177-D181 PolarHBondContact O-N 3.43Å
178	V	86.2	Confident	78.8	Confident	61 Å²	61	41.3 Å²	41.3	37%	0.37	25%	0.246	S	C	.	.	H	α-helix	trans	-63.6	-44.6	174.3	170.3	0	0	0	0	110.3	I174 V176 D180 D181 V182	I174-V178 HydrophobicContact CG2-CG2 4.05Å; I174-V178 WeakPolarHBondContact O-CB 3.41Å; I174-V178 VanDerWaalsContact O-CG2 3.23Å; I174-V178 WeakPolarHBondContact O-CG2 3.36Å; I174-V178 PolarHBondContact O-N 3.49Å; V176-V178 VanDerWaalsContact C-N 3.35Å; V176-V178 PolarHBondContact O-N 3.42Å; V178-D180 VanDerWaalsContact C-N 3.27Å; V178-D180 PolarHBondContact O-N 2.9Å; V178-D181 PolarHBondContact O-N 3Å; V178-V182 HydrophobicContact CG1-CG2 4.03Å; V178-V182 WeakPolarHBondContact O-CB 3.48Å; V178-V182 WeakPolarHBondContact O-CG2 3.28Å; V178-V182 PolarHBondContact O-N 2.88Å
179	K	82.8	Confident	76.3	Confident	36 Å²	36	46.9 Å²	46.9	16%	0.157	28%	0.281	C	S	.	.	H	α-helix	trans	-57.3	-42.4	174.8	-176.7	-153.9	72.4	66.7	0	111	S175 V176 V182 L183 L209	S175-K179 VanDerWaalsContact O-CB 3.27Å; S175-K179 WeakPolarHBondContact O-CB 3.26Å; S175-K179 PolarHBondContact O-N 3.4Å; V176-K179 WeakPolarHBondContact O-CB 3.45Å; V176-K179 PolarHBondContact O-N 2.93Å; K179-V182 PolarHBondContact O-N 2.84Å; K179-L183 HydrophobicContact CG-CD1 4.03Å; K179-L183 VanDerWaalsContact O-CB 3.31Å; K179-L183 WeakPolarHBondContact O-CB 3.08Å; K179-L183 WeakPolarHBondContact O-CD1 3.27Å; K179-L183 PolarHBondContact O-N 3.34Å; K179-L209 HydrophobicContact CB-CD2 4.46Å; K179-L209 HydrophobicContact CD-CD2 3.47Å; K179-L209 VanDerWaalsContact CD-CD2 3.47Å; K179-L209 HydrophobicContact CG-CD2 4.16Å
180	D	80.8	Confident	74.1	Confident	9 Å²	9	53.5 Å²	53.5	5%	0.048	32%	0.316	C	S	.	.	H	α-helix	trans	-73.4	-34.7	-178.9	-61.9	-39	0	0	0	112.9	Y130 V176 L177 V178 Y184	Y130-D180 WeakPolarHBondContact CE2-OD2 3.24Å; Y130-D180 VanDerWaalsContact OH-CG 3.32Å; Y130-D180 PolarHBondContact OH-OD1 3.24Å; Y130-D180 VanDerWaalsContact OH-OD1 3.14Å; Y130-D180 PolarHBondContact OH-OD2 2.91Å; V176-D180 VanDerWaalsContact O-CG 3.29Å; V176-D180 PolarHBondContact O-N 3.05Å; V176-D180 VanDerWaalsContact O-OD2 3.06Å; L177-D180 PolarHBondContact O-N 3.26Å; V178-D180 VanDerWaalsContact C-N 3.27Å; V178-D180 PolarHBondContact O-N 2.9Å; D180-Y184 HydrophobicContact CB-CD2 4.27Å; D180-Y184 VanDerWaalsContact O-CB 3.25Å; D180-Y184 WeakPolarHBondContact O-CB 3.3Å; D180-Y184 VanDerWaalsContact O-CD2 3.3Å; D180-Y184 WeakPolarHBondContact O-CD2 3.4Å; D180-Y184 PolarHBondContact O-N 2.89Å
181	D	76.3	Confident	72	Confident	115 Å²	115	60.2 Å²	60.2	62%	0.615	35%	0.346	S	S	*	.	H	α-helix	trans	-66.2	-42	171.8	-167.2	58.6	0	0	0	110.9	L177 V178 S185	L177-D181 WeakPolarHBondContact O-CB 3.19Å; L177-D181 PolarHBondContact O-N 3.43Å; V178-D181 PolarHBondContact O-N 3Å; D181-S185 WeakPolarHBondContact O-CA 3.33Å; D181-S185 VanDerWaalsContact O-CB 3.24Å; D181-S185 WeakPolarHBondContact O-CB 3.4Å; D181-S185 PolarHBondContact O-N 3.31Å
182	V	68.3	Low	70.3	Confident	16 Å²	16	61.6 Å²	61.6	10%	0.097	36%	0.356	C	S	.	.	H	α-helix	trans	-64.5	-45.8	176.5	163.7	0	0	0	0	111.8	V178 K179	V178-V182 HydrophobicContact CG1-CG2 4.03Å; V178-V182 WeakPolarHBondContact O-CB 3.48Å; V178-V182 WeakPolarHBondContact O-CG2 3.28Å; V178-V182 PolarHBondContact O-N 2.88Å; K179-V182 PolarHBondContact O-N 2.84Å
183	L	64.8	Low	68.3	Low	15 Å²	15	62.8 Å²	62.8	8%	0.079	37%	0.366	C	S	.	.	H	α-helix	trans	-80.3	-24.2	-177	-95.8	67.2	0	0	0	113.2	H22 P23 K179	H22-L183 PolarHBondContact CD2-O 2.99Å; H22-L183 PolarHBondContact NE2-O 3.36Å; P23-L183 WeakPolarHBondContact CD-O 3.4Å; K179-L183 HydrophobicContact CG-CD1 4.03Å; K179-L183 VanDerWaalsContact O-CB 3.31Å; K179-L183 WeakPolarHBondContact O-CB 3.08Å; K179-L183 WeakPolarHBondContact O-CD1 3.27Å; K179-L183 PolarHBondContact O-N 3.34Å
184	Y	65	Low	66.3	Low	107 Å²	107	66.9 Å²	66.9	42%	0.42	39%	0.388	S	S	.	.	H	α-helix	trans	-126.6	18.5	-173	-59.4	-90	0	0	0	113.6	K127 D180 S186	K127-Y184 HydrophobicContact CD-CD2 4.32Å; K127-Y184 HydrophobicContact CD-CE2 4.14Å; D180-Y184 HydrophobicContact CB-CD2 4.27Å; D180-Y184 VanDerWaalsContact O-CB 3.25Å; D180-Y184 WeakPolarHBondContact O-CB 3.3Å; D180-Y184 VanDerWaalsContact O-CD2 3.3Å; D180-Y184 WeakPolarHBondContact O-CD2 3.4Å; D180-Y184 PolarHBondContact O-N 2.89Å; Y184-S186 PolarHBondContact O-N 3.45Å
185	S	58.2	Low	64.4	Low	47 Å²	47	69.7 Å²	69.7	33%	0.329	40%	0.4	S	S	.	.			trans	-56.2	114.2	171.7	-168.4	0	0	0	0	108	D181 S187	D181-S185 WeakPolarHBondContact O-CA 3.33Å; D181-S185 VanDerWaalsContact O-CB 3.24Å; D181-S185 WeakPolarHBondContact O-CB 3.4Å; D181-S185 PolarHBondContact O-N 3.31Å; S185-S187 PolarHBondContact O-N 3.38Å; S185-S187 PolarHBondContact OG-OG 2.69Å
186	S	48.5	Very low	62.7	Low	123 Å²	123	74.3 Å²	74.3	86%	0.86	43%	0.43	S	S	*	.			trans	-70.7	36	-177.2	-179.8	0	0	0	0	112.6	Y184 G188	Y184-S186 PolarHBondContact O-N 3.45Å; S186-G188 PolarHBondContact O-N 3.34Å
187	S	43.6	Very low	61.2	Low	95 Å²	95	76.9 Å²	76.9	66%	0.664	45%	0.449	S	S	*	.			trans	-101.6	74.6	-169.5	-54.2	0	0	0	0	110.6	S185	S185-S187 PolarHBondContact O-N 3.38Å; S185-S187 PolarHBondContact OG-OG 2.69Å
188	G	41.7	Very low	59.9	Low	56 Å²	56	74.9 Å²	74.9	58%	0.577	44%	0.438	S	S	*	.			trans	66.3	112.1	155.4	0	0	0	0	0	116.9	S186 L190	S186-G188 PolarHBondContact O-N 3.34Å; G188-L190 PolarHBondContact O-N 3.18Å
189	T	45	Very low	59.1	Low	119 Å²	119	75.3 Å²	75.3	73%	0.73	43%	0.433	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.5	20.8	167	44.9	0	0	0	0	115.9
190	L	48.3	Very low	58.7	Low	149 Å²	149	78.1 Å²	78.1	78%	0.78	45%	0.453	S	S	*	.	T	Hydrogen-bonded Turn	trans	-111.9	-25.8	-169.3	-148.9	71.3	0	0	0	115.2	G188	G188-L190 PolarHBondContact O-N 3.18Å
191	H	52.4	Low	58.5	Low	166 Å²	166	78.3 Å²	78.3	77%	0.769	46%	0.457	S	S	*	.			trans	-135.9	93.9	179.9	-77.2	1.7	0	0	0	111	P193	H191-P193 WeakPolarHBondContact O-CD 3.49Å
192	C	59	Low	58.6	Low	37 Å²	37	73 Å²	73	25%	0.25	43%	0.429	C	S	.	.			trans	-74.4	111.4	156.9	-69.9	0	0	0	0	107.2	C25 D194	C25-C192 WeakPolarHBondContact CA-SG 3.43Å; C25-C192 HydrophobicContact CB-CB 3.87Å; C25-C192 WeakPolarHBondContact CB-SG 3.48Å; C25-C192 WeakPolarHBondContact SG-CA 3.28Å; C25-C192 WeakPolarHBondContact SG-CB 3.3Å; C25-C192 CovalentContact SG-SG 2.06Å; C25-C192 PolarHBondContact SG-SG 3.44Å; C192-D194 PolarHBondContact O-N 3.39Å
193	P	53.3	Low	59.3	Low	45 Å²	45	73.8 Å²	73.8	29%	0.292	43%	0.431	S	S	.	.			trans	-71.4	103.8	177.9	28.2	-31.2	0	0	0	108.3	H191 Q195 S198	H191-P193 WeakPolarHBondContact O-CD 3.49Å; P193-Q195 PolarHBondContact O-N 3.12Å; P193-S198 PolarHBondContact O-OG 3.01Å
194	D	53.1	Low	60.2	Low	87 Å²	87	78.7 Å²	78.7	47%	0.465	46%	0.457	S	S	.	.			trans	-58.4	9.2	168.5	-73.1	-19.6	0	0	0	113.6	L29 Q32 C192	L29-D194 VanDerWaalsContact CD2-OD1 3.29Å; L29-D194 WeakPolarHBondContact CD2-OD1 3.31Å; Q32-D194 PolarHBondContact NE2-OD2 3.42Å; C192-D194 PolarHBondContact O-N 3.39Å
195	Q	53.9	Low	61.1	Low	119 Å²	119	74.6 Å²	74.6	56%	0.556	44%	0.444	S	S	*	.			trans	-82.8	126.6	-177.7	-89.4	177	2.9	0	0	111.3	P193 S197 S198	P193-Q195 PolarHBondContact O-N 3.12Å; Q195-S197 PolarHBondContact O-N 2.95Å; Q195-S198 PolarHBondContact O-N 3.44Å; Q195-S198 PolarHBondContact O-OG 2.94Å
196	P	56.6	Low	62.4	Low	102 Å²	102	72.8 Å²	72.8	66%	0.662	43%	0.43	S	S	*	.	H	α-helix	trans	-57	-17.6	175.7	19.8	-30.7	0	0	0	113.8	W199 V200	P196-W199 PolarHBondContact O-N 3.35Å; P196-V200 PolarHBondContact O-N 2.91Å
197	S	57.5	Low	64.4	Low	68 Å²	68	68.2 Å²	68.2	48%	0.476	40%	0.397	S	S	.	.	H	α-helix	trans	-65.6	-33.1	174.9	58	0	0	0	0	113.8	Q195 W199 V200 G201	Q195-S197 PolarHBondContact O-N 2.95Å; S197-W199 VanDerWaalsContact C-N 3.28Å; S197-W199 PolarHBondContact O-N 3.32Å; S197-V200 PolarHBondContact O-N 3.26Å; S197-G201 PolarHBondContact O-N 2.92Å
198	S	62.3	Low	66.7	Low	0 Å²	0	66.9 Å²	66.9	0%	0	38%	0.379	C	S	.	.	H	α-helix	trans	-68.8	-30.6	178.1	65	0	0	0	0	111.8	I21 P193 Q195 G201 C202	I21-S198 WeakPolarHBondContact CD1-OG 3.44Å; I21-S198 WeakPolarHBondContact CG1-OG 3.22Å; P193-S198 PolarHBondContact O-OG 3.01Å; Q195-S198 PolarHBondContact O-N 3.44Å; Q195-S198 PolarHBondContact O-OG 2.94Å; S198-G201 PolarHBondContact O-N 3.28Å; S198-C202 PolarHBondContact O-N 3.47Å; S198-C202 VanDerWaalsContact O-N 3.07Å
199	W	68.9	Low	69.1	Low	71 Å²	71	64.7 Å²	64.7	27%	0.269	35%	0.354	S	S	.	.	H	α-helix	trans	-70.9	-39.4	178.8	-60.9	64.5	0	0	0	111.1	I21 L29 P196 S197 G201 C202 K203 G270	I21-W199 HydrophobicContact CD1-CB 4.26Å; I21-W199 VanDerWaalsContact CD1-CD1 3.44Å; I21-W199 HydrophobicContact CD1-CD2 3.66Å; I21-W199 HydrophobicContact CD1-CG 3.54Å; I21-W199 HydrophobicContact CD1-CZ2 4.32Å; L29-W199 HydrophobicContact CD1-CH2 3.94Å; L29-W199 HydrophobicContact CD1-CZ2 3.45Å; L29-W199 VanDerWaalsContact CD1-CZ2 3.45Å; P196-W199 PolarHBondContact O-N 3.35Å; S197-W199 VanDerWaalsContact C-N 3.28Å; S197-W199 PolarHBondContact O-N 3.32Å; W199-G201 VanDerWaalsContact C-N 3.32Å; W199-G201 PolarHBondContact O-N 2.94Å; W199-C202 PolarHBondContact O-N 3.44Å; W199-K203 WeakPolarHBondContact O-CB 3.21Å; W199-K203 VanDerWaalsContact O-CG 3.23Å; W199-K203 WeakPolarHBondContact O-CG 3.4Å; W199-K203 PolarHBondContact O-N 3.39Å; W199-G270 VanDerWaalsContact CZ3-C 3.45Å; W199-G270 VanDerWaalsContact CZ3-N 3.31Å
200	V	76.4	Confident	71.3	Confident	95 Å²	95	61.4 Å²	61.4	58%	0.576	33%	0.331	S	S	*	.	H	α-helix	trans	-62.2	-42.3	175.5	179.5	0	0	0	0	110.7	P196 S197 K203 L204	P196-V200 PolarHBondContact O-N 2.91Å; S197-V200 PolarHBondContact O-N 3.26Å; V200-K203 PolarHBondContact O-N 2.83Å; V200-L204 WeakPolarHBondContact O-CB 3.44Å; V200-L204 PolarHBondContact O-N 2.91Å
201	G	75.4	Confident	73.5	Confident	13 Å²	13	55.8 Å²	55.8	13%	0.134	30%	0.299	C	S	.	.	H	α-helix	trans	-59.8	-48.3	175.4	0	0	0	0	0	112.9	S197 S198 W199 L204 S205	S197-G201 PolarHBondContact O-N 2.92Å; S198-G201 PolarHBondContact O-N 3.28Å; W199-G201 VanDerWaalsContact C-N 3.32Å; W199-G201 PolarHBondContact O-N 2.94Å; G201-L204 PolarHBondContact O-N 3.37Å; G201-S205 WeakPolarHBondContact O-CB 3.29Å; G201-S205 PolarHBondContact O-N 3.18Å
202	C	78.4	Confident	75.5	Confident	4 Å²	4	47.9 Å²	47.9	3%	0.027	26%	0.263	C	S	.	.	H	α-helix	trans	-62.7	-46.7	177.3	-165.3	0	0	0	0	112.1	S198 W199 L204 S205 L206 C271	S198-C202 PolarHBondContact O-N 3.47Å; S198-C202 VanDerWaalsContact O-N 3.07Å; W199-C202 PolarHBondContact O-N 3.44Å; C202-L204 PolarHBondContact O-N 3.35Å; C202-S205 PolarHBondContact O-N 2.89Å; C202-L206 WeakPolarHBondContact O-CG 3.37Å; C202-L206 PolarHBondContact O-N 3.5Å; C202-C271 VanDerWaalsContact C-SG 3.59Å; C202-C271 HydrophobicContact CB-CB 3.84Å; C202-C271 WeakPolarHBondContact CB-SG 3.27Å; C202-C271 WeakPolarHBondContact SG-CB 3.38Å; C202-C271 CovalentContact SG-SG 2.02Å; C202-C271 PolarHBondContact SG-SG 3.08Å
203	K	82.8	Confident	77.1	Confident	32 Å²	32	47.8 Å²	47.8	14%	0.139	26%	0.26	C	S	.	.	H	α-helix	trans	-57.8	-47.8	175.8	-73.2	174.7	-177.3	-175.8	0	111.4	W199 V200 S205 L206 V207 D268 G270 W272	W199-K203 WeakPolarHBondContact O-CB 3.21Å; W199-K203 VanDerWaalsContact O-CG 3.23Å; W199-K203 WeakPolarHBondContact O-CG 3.4Å; W199-K203 PolarHBondContact O-N 3.39Å; V200-K203 PolarHBondContact O-N 2.83Å; K203-S205 PolarHBondContact O-N 3.44Å; K203-L206 PolarHBondContact O-N 3.4Å; K203-V207 VanDerWaalsContact O-CG2 3.25Å; K203-V207 WeakPolarHBondContact O-CG2 3.34Å; K203-V207 PolarHBondContact O-N 3.22Å; K203-D268 PolarHBondContact NZ-O 3.47Å; K203-D268 VanDerWaalsContact NZ-O 3.1Å; K203-D268 IonicContact NZ-OD1 3.63Å; K203-D268 PolarHBondContact NZ-OD1 2.92Å; K203-D268 IonicContact NZ-OD2 3.09Å; K203-D268 PolarHBondContact NZ-OD2 3.31Å; K203-G270 WeakPolarHBondContact CE-O 3.37Å; K203-W272 HydrophobicContact CD-CZ2 4.41Å; K203-W272 HydrophobicContact CG-CD2 4.19Å; K203-W272 HydrophobicContact CG-CG 4.33Å
204	L	84.7	Confident	79	Confident	117 Å²	117	45.7 Å²	45.7	61%	0.613	25%	0.246	S	C	*	.	H	α-helix	trans	-64.6	-41.1	179.9	-175.1	63.1	0	0	0	112.1	V200 G201 C202 V207 F208	V200-L204 WeakPolarHBondContact O-CB 3.44Å; V200-L204 PolarHBondContact O-N 2.91Å; G201-L204 PolarHBondContact O-N 3.37Å; C202-L204 PolarHBondContact O-N 3.35Å; L204-V207 PolarHBondContact O-N 3.28Å; L204-F208 WeakPolarHBondContact O-CB 3.21Å; L204-F208 PolarHBondContact O-N 2.9Å
205	S	83.6	Confident	81	Confident	22 Å²	22	41.6 Å²	41.6	15%	0.154	22%	0.224	C	C	.	.	H	α-helix	trans	-61.2	-44.2	176	-173.6	0	0	0	0	111.6	G201 C202 K203 F208 L209	G201-S205 WeakPolarHBondContact O-CB 3.29Å; G201-S205 PolarHBondContact O-N 3.18Å; C202-S205 PolarHBondContact O-N 2.89Å; K203-S205 PolarHBondContact O-N 3.44Å; S205-F208 PolarHBondContact O-N 2.99Å; S205-L209 WeakPolarHBondContact O-CB 3.41Å; S205-L209 PolarHBondContact O-N 2.83Å
206	L	86	Confident	82.9	Confident	8 Å²	8	35.9 Å²	35.9	4%	0.042	20%	0.198	C	C	.	.	H	α-helix	trans	-65.8	-42.9	175.9	-71.6	-177.9	0	0	0	112.7	C202 K203 F208 L209 Q210 C271 W272 D273	C202-L206 WeakPolarHBondContact O-CG 3.37Å; C202-L206 PolarHBondContact O-N 3.5Å; K203-L206 PolarHBondContact O-N 3.4Å; L206-F208 VanDerWaalsContact C-N 3.28Å; L206-F208 PolarHBondContact O-N 3.38Å; L206-L209 HydrophobicContact CD2-CD2 4.3Å; L206-L209 WeakPolarHBondContact O-CB 3.34Å; L206-L209 PolarHBondContact O-N 2.99Å; L206-Q210 VanDerWaalsContact O-CG 3.31Å; L206-Q210 WeakPolarHBondContact O-CG 3.37Å; L206-Q210 PolarHBondContact O-N 3.39Å; L206-C271 WeakPolarHBondContact CD1-SG 3.12Å; L206-W272 HydrophobicContact CD1-CB 4.06Å; L206-D273 HydrophobicContact CD1-CB 4.14Å
207	V	90.6	Very high	84.6	Confident	27 Å²	27	31.5 Å²	31.5	16%	0.164	17%	0.168	C	C	.	.	H	α-helix	trans	-57.6	-45.5	174.1	171.2	0	0	0	0	110.4	K203 L204 Q210 Y211 I256 W259 T260 W272	K203-V207 VanDerWaalsContact O-CG2 3.25Å; K203-V207 WeakPolarHBondContact O-CG2 3.34Å; K203-V207 PolarHBondContact O-N 3.22Å; L204-V207 PolarHBondContact O-N 3.28Å; V207-Q210 PolarHBondContact O-N 3.24Å; V207-Y211 WeakPolarHBondContact O-CB 3.48Å; V207-Y211 PolarHBondContact O-N 2.84Å; V207-I256 HydrophobicContact CG1-CG2 3.84Å; V207-W259 HydrophobicContact CG2-CZ3 3.84Å; V207-T260 HydrophobicContact CG2-CG2 4.48Å; V207-W272 HydrophobicContact CG2-CE3 3.93Å; V207-W272 HydrophobicContact CG2-CZ3 3.52Å
208	F	91.9	Very high	86.3	Confident	67 Å²	67	28.8 Å²	28.8	29%	0.294	15%	0.148	S	C	.	.	H	α-helix	trans	-64.8	-41	178.8	-176.4	-109.5	0	0	0	112.4	L171 S175 L204 S205 L206 Y211 C212	L171-F208 HydrophobicContact CD2-CZ 4.4Å; S175-F208 WeakPolarHBondContact OG-CD1 3.29Å; S175-F208 WeakPolarHBondContact OG-CE1 3.47Å; L204-F208 WeakPolarHBondContact O-CB 3.21Å; L204-F208 PolarHBondContact O-N 2.9Å; S205-F208 PolarHBondContact O-N 2.99Å; L206-F208 VanDerWaalsContact C-N 3.28Å; L206-F208 PolarHBondContact O-N 3.38Å; F208-Y211 WeakPolarHBondContact O-CB 3.49Å; F208-Y211 PolarHBondContact O-N 2.85Å; F208-C212 PolarHBondContact O-N 3.49Å; F208-C212 PolarHBondContact O-SG 3.45Å
209	L	90.8	Very high	87.9	Confident	10 Å²	10	28.8 Å²	28.8	5%	0.052	15%	0.148	C	C	.	.	H	α-helix	trans	-59.1	-51.5	173.5	174.6	76.3	0	0	0	111.4	V176 K179 S205 L206 Y211 C212 I213	V176-L209 HydrophobicContact CG2-CD1 3.78Å; K179-L209 HydrophobicContact CB-CD2 4.46Å; K179-L209 HydrophobicContact CD-CD2 3.47Å; K179-L209 VanDerWaalsContact CD-CD2 3.47Å; K179-L209 HydrophobicContact CG-CD2 4.16Å; S205-L209 WeakPolarHBondContact O-CB 3.41Å; S205-L209 PolarHBondContact O-N 2.83Å; L206-L209 HydrophobicContact CD2-CD2 4.3Å; L206-L209 WeakPolarHBondContact O-CB 3.34Å; L206-L209 PolarHBondContact O-N 2.99Å; L209-Y211 VanDerWaalsContact C-N 3.25Å; L209-Y211 PolarHBondContact O-N 3.36Å; L209-C212 PolarHBondContact O-N 2.9Å; L209-C212 VanDerWaalsContact O-N 3.09Å; L209-I213 HydrophobicContact CD1-CD1 4.16Å; L209-I213 HydrophobicContact CD2-CD1 4.49Å; L209-I213 HydrophobicContact CG-CD1 3.93Å; L209-I213 WeakPolarHBondContact O-CG1 3.28Å; L209-I213 PolarHBondContact O-N 3.27Å
210	Q	91.6	Very high	88.9	Confident	50 Å²	50	25.5 Å²	25.5	23%	0.234	14%	0.136	C	C	.	.	H	α-helix	trans	-60.6	-39.3	-180	-66.5	-60	-15.8	0	0	110.9	L206 V207 I213 M214 I256 W259 I284	L206-Q210 VanDerWaalsContact O-CG 3.31Å; L206-Q210 WeakPolarHBondContact O-CG 3.37Å; L206-Q210 PolarHBondContact O-N 3.39Å; V207-Q210 PolarHBondContact O-N 3.24Å; Q210-I213 PolarHBondContact O-N 2.98Å; Q210-M214 VanDerWaalsContact O-CB 3.27Å; Q210-M214 WeakPolarHBondContact O-CB 3.32Å; Q210-M214 PolarHBondContact O-N 3.33Å; Q210-I256 HydrophobicContact CB-CD1 3.72Å; Q210-W259 HydrophobicContact CG-CH2 4.11Å; Q210-W259 HydrophobicContact CG-CZ3 4.32Å; Q210-I284 HydrophobicContact CB-CD1 4.05Å; Q210-I284 HydrophobicContact CG-CD1 3.95Å
211	Y	94.8	Very high	89.7	Confident	31 Å²	31	21.7 Å²	21.7	12%	0.122	11%	0.112	C	C	.	.	H	α-helix	trans	-59.9	-47.2	171.5	177	-98.5	0	0	0	113.1	V207 F208 L209 I213 M214 A215 W249 P252 T253 I256	V207-Y211 WeakPolarHBondContact O-CB 3.48Å; V207-Y211 PolarHBondContact O-N 2.84Å; F208-Y211 WeakPolarHBondContact O-CB 3.49Å; F208-Y211 PolarHBondContact O-N 2.85Å; L209-Y211 VanDerWaalsContact C-N 3.25Å; L209-Y211 PolarHBondContact O-N 3.36Å; Y211-I213 VanDerWaalsContact C-N 3.34Å; Y211-I213 PolarHBondContact O-N 3.33Å; Y211-M214 PolarHBondContact O-N 2.87Å; Y211-A215 VanDerWaalsContact O-CB 3.25Å; Y211-A215 WeakPolarHBondContact O-CB 3.33Å; Y211-A215 PolarHBondContact O-N 3.23Å; Y211-W249 HydrophobicContact CE1-CE3 4.33Å; Y211-W249 HydrophobicContact CE1-CZ3 4.39Å; Y211-W249 PolarHBondContact OH-O 3.21Å; Y211-P252 HydrophobicContact CD2-CB 4.16Å; Y211-P252 HydrophobicContact CE2-CB 3.89Å; Y211-T253 WeakPolarHBondContact CE2-OG1 3.25Å; Y211-I256 HydrophobicContact CD2-CG1 4.21Å
212	C	94.8	Very high	90.5	Very high	1 Å²	1	21.1 Å²	21.1	1%	0.007	11%	0.105	C	C	.	.	H	α-helix	trans	-64.1	-38.9	179.8	-65.7	0	0	0	0	112.3	L171 R172 S175 F208 L209 N216	L171-C212 HydrophobicContact CB-CB 4.41Å; R172-C212 HydrophobicContact CB-CB 4.47Å; S175-C212 PolarHBondContact OG-SG 3.44Å; F208-C212 PolarHBondContact O-N 3.49Å; F208-C212 PolarHBondContact O-SG 3.45Å; L209-C212 PolarHBondContact O-N 2.9Å; L209-C212 VanDerWaalsContact O-N 3.09Å; C212-N216 WeakPolarHBondContact O-CB 3.25Å; C212-N216 PolarHBondContact O-N 2.97Å
213	I	91.9	Very high	91.1	Very high	34 Å²	34	21.2 Å²	21.2	17%	0.174	11%	0.105	C	C	.	.	H	α-helix	trans	-63.4	-50.4	174.7	-66.5	168.3	0	0	0	110.1	R172 L209 Q210 Y211 N216 F217	R172-I213 HydrophobicContact CG-CG1 4.45Å; L209-I213 HydrophobicContact CD1-CD1 4.16Å; L209-I213 HydrophobicContact CD2-CD1 4.49Å; L209-I213 HydrophobicContact CG-CD1 3.93Å; L209-I213 WeakPolarHBondContact O-CG1 3.28Å; L209-I213 PolarHBondContact O-N 3.27Å; Q210-I213 PolarHBondContact O-N 2.98Å; Y211-I213 VanDerWaalsContact C-N 3.34Å; Y211-I213 PolarHBondContact O-N 3.33Å; I213-N216 WeakPolarHBondContact O-CB 3.38Å; I213-N216 PolarHBondContact O-N 3.13Å; I213-F217 HydrophobicContact CG2-CD2 4.01Å; I213-F217 HydrophobicContact CG2-CE2 3.78Å; I213-F217 VanDerWaalsContact O-CD2 3.29Å; I213-F217 WeakPolarHBondContact O-CD2 3.44Å; I213-F217 PolarHBondContact O-N 2.94Å
214	M	92.7	Very high	91.4	Very high	1 Å²	1	19.7 Å²	19.7	1%	0.005	10%	0.099	C	C	.	.	H	α-helix	trans	-58.8	-51.6	179.1	-170.5	80.8	74.9	0	0	111	Q210 Y211 N216 F217 F218 P252 C255 I256 I284 P287 I288	Q210-M214 VanDerWaalsContact O-CB 3.27Å; Q210-M214 WeakPolarHBondContact O-CB 3.32Å; Q210-M214 PolarHBondContact O-N 3.33Å; Y211-M214 PolarHBondContact O-N 2.87Å; M214-N216 VanDerWaalsContact C-N 3.25Å; M214-N216 PolarHBondContact O-N 3.13Å; M214-F217 PolarHBondContact O-N 3.27Å; M214-F217 VanDerWaalsContact O-N 3.1Å; M214-F218 HydrophobicContact CG-CD2 3.88Å; M214-F218 HydrophobicContact CG-CE2 3.81Å; M214-F218 VanDerWaalsContact O-CD2 3.32Å; M214-F218 WeakPolarHBondContact O-CD2 3.48Å; M214-F218 PolarHBondContact O-N 3.32Å; M214-F218 HydrophobicContact SD-CD2 4.3Å; M214-F218 HydrophobicContact SD-CE2 3.73Å; M214-P252 HydrophobicContact CB-CB 4.16Å; M214-P252 HydrophobicContact CG-CB 3.73Å; M214-P252 HydrophobicContact CG-CG 4.3Å; M214-C255 HydrophobicContact CE-CB 3.92Å; M214-C255 HydrophobicContact SD-CB 4.42Å; M214-I256 HydrophobicContact CB-CD1 4.37Å; M214-I256 HydrophobicContact CB-CG1 4.43Å; M214-I256 HydrophobicContact CE-CD1 3.89Å; M214-I256 HydrophobicContact CE-CG1 4.43Å; M214-I284 HydrophobicContact CE-CB 4.45Å; M214-I284 HydrophobicContact CE-CG1 4.24Å; M214-I284 HydrophobicContact CE-CG2 4.19Å; M214-P287 HydrophobicContact SD-CB 4.12Å; M214-I288 HydrophobicContact CE-CD1 4.5Å; M214-I288 HydrophobicContact CE-CG1 4.35Å; M214-I288 HydrophobicContact SD-CD1 4.29Å; M214-I288 HydrophobicContact SD-CG1 3.66Å
215	A	95	Very high	91.7	Very high	1 Å²	1	16.2 Å²	16.2	1%	0.008	8%	0.081	C	C	.	.	H	α-helix	trans	-57.7	-38.3	178.2	0	0	0	0	0	112	Y211 F218 W219 W249 P252	Y211-A215 VanDerWaalsContact O-CB 3.25Å; Y211-A215 WeakPolarHBondContact O-CB 3.33Å; Y211-A215 PolarHBondContact O-N 3.23Å; A215-F218 PolarHBondContact O-N 3.45Å; A215-W219 WeakPolarHBondContact O-CB 3.44Å; A215-W219 PolarHBondContact O-N 3.02Å; A215-W249 HydrophobicContact CB-CE3 3.95Å; A215-W249 HydrophobicContact CB-CZ3 3.76Å; A215-P252 HydrophobicContact CB-CB 4.23Å; A215-P252 HydrophobicContact CB-CG 4.14Å
216	N	94.1	Very high	91.9	Very high	0 Å²	0	16 Å²	16	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-61.5	-45.7	175.3	-178	-117.2	0	0	0	112.3	S168 F169 R172 C212 I213 M214 F218 W219 L220	S168-N216 PolarHBondContact OG-ND2 3.09Å; F169-N216 VanDerWaalsContact CD1-ND2 3.28Å; F169-N216 WeakPolarHBondContact CD1-ND2 3.46Å; F169-N216 WeakPolarHBondContact CD2-ND2 3.37Å; F169-N216 VanDerWaalsContact CE1-ND2 3.34Å; F169-N216 WeakPolarHBondContact CE1-ND2 3.4Å; F169-N216 VanDerWaalsContact CG-ND2 3.33Å; F169-N216 WeakPolarHBondContact CG-ND2 3.26Å; F169-N216 WeakPolarHBondContact CZ-ND2 3.3Å; R172-N216 HydrophobicContact CB-CB 4.47Å; R172-N216 PolarHBondContact NH1-OD1 3.35Å; C212-N216 WeakPolarHBondContact O-CB 3.25Å; C212-N216 PolarHBondContact O-N 2.97Å; I213-N216 WeakPolarHBondContact O-CB 3.38Å; I213-N216 PolarHBondContact O-N 3.13Å; M214-N216 VanDerWaalsContact C-N 3.25Å; M214-N216 PolarHBondContact O-N 3.13Å; N216-F218 PolarHBondContact O-N 3.44Å; N216-W219 PolarHBondContact O-N 3.48Å; N216-L220 WeakPolarHBondContact O-CG 3.28Å; N216-L220 PolarHBondContact O-N 3.1Å
217	F	92.3	Very high	91.9	Very high	10 Å²	10	17.8 Å²	17.8	4%	0.044	9%	0.086	C	C	.	.	H	α-helix	trans	-62.2	-41.8	175.4	-78.5	-70.3	0	0	0	112.8	I213 M214 L220 L221 I288 S291 I292 Y341	I213-F217 HydrophobicContact CG2-CD2 4.01Å; I213-F217 HydrophobicContact CG2-CE2 3.78Å; I213-F217 VanDerWaalsContact O-CD2 3.29Å; I213-F217 WeakPolarHBondContact O-CD2 3.44Å; I213-F217 PolarHBondContact O-N 2.94Å; M214-F217 PolarHBondContact O-N 3.27Å; M214-F217 VanDerWaalsContact O-N 3.1Å; F217-L220 WeakPolarHBondContact O-CB 3.47Å; F217-L220 PolarHBondContact O-N 3.23Å; F217-L221 PolarHBondContact O-N 2.99Å; F217-I288 HydrophobicContact CD1-CG2 4.41Å; F217-I288 HydrophobicContact CD2-CD1 4.46Å; F217-I288 HydrophobicContact CD2-CG1 4.32Å; F217-I288 HydrophobicContact CD2-CG2 3.82Å; F217-I288 HydrophobicContact CE1-CG2 4.38Å; F217-I288 HydrophobicContact CE2-CG2 3.79Å; F217-I288 HydrophobicContact CG-CG2 4.15Å; F217-I288 HydrophobicContact CZ-CG2 4.08Å; F217-S291 PolarHBondContact O-OG 2.93Å; F217-I292 HydrophobicContact CD1-CD1 4.19Å; F217-I292 HydrophobicContact CD1-CG1 3.79Å; F217-I292 HydrophobicContact CE1-CD1 3.73Å; F217-I292 HydrophobicContact CE1-CG1 3.76Å; F217-I292 HydrophobicContact CZ-CD1 4.24Å; F217-Y341 AromaticContact CE1-CD2 3.8Å; F217-Y341 HydrophobicContact CE1-CD2 3.8Å; F217-Y341 AromaticContact CE1-CE2 3.79Å; F217-Y341 HydrophobicContact CE1-CE2 3.79Å; F217-Y341 HydrophobicContact CE1-CG 4.23Å; F217-Y341 HydrophobicContact CZ-CD1 4.34Å; F217-Y341 HydrophobicContact CZ-CD2 4.3Å; F217-Y341 HydrophobicContact CZ-CE1 4.09Å; F217-Y341 HydrophobicContact CZ-CE2 4.08Å; F217-Y341 HydrophobicContact CZ-CG 4.46Å; F217-Y341 AromaticContact CZ-CZ 3.99Å
218	F	93.9	Very high	91.7	Very high	10 Å²	10	18.5 Å²	18.5	4%	0.044	9%	0.088	C	C	.	.	H	α-helix	trans	-69.4	-33.8	177.4	-82.9	-80.3	0	0	0	112.9	M214 A215 N216 L221 V222 I247 L251 P252 P287	M214-F218 HydrophobicContact CG-CD2 3.88Å; M214-F218 HydrophobicContact CG-CE2 3.81Å; M214-F218 VanDerWaalsContact O-CD2 3.32Å; M214-F218 WeakPolarHBondContact O-CD2 3.48Å; M214-F218 PolarHBondContact O-N 3.32Å; M214-F218 HydrophobicContact SD-CD2 4.3Å; M214-F218 HydrophobicContact SD-CE2 3.73Å; A215-F218 PolarHBondContact O-N 3.45Å; N216-F218 PolarHBondContact O-N 3.44Å; F218-L221 HydrophobicContact CD1-CD2 4.19Å; F218-L221 HydrophobicContact CE1-CD2 4.4Å; F218-L221 WeakPolarHBondContact O-CB 3.49Å; F218-L221 PolarHBondContact O-N 3.22Å; F218-V222 WeakPolarHBondContact O-CG2 3.3Å; F218-V222 PolarHBondContact O-N 3.4Å; F218-I247 HydrophobicContact CD1-CG2 4.31Å; F218-L251 HydrophobicContact CD1-CB 4.42Å; F218-L251 HydrophobicContact CD1-CD2 3.97Å; F218-L251 HydrophobicContact CD1-CG 4.33Å; F218-L251 HydrophobicContact CE1-CB 4.24Å; F218-L251 HydrophobicContact CE1-CD2 3.21Å; F218-L251 HydrophobicContact CE1-CG 3.66Å; F218-L251 HydrophobicContact CZ-CD2 3.72Å; F218-L251 HydrophobicContact CZ-CG 3.75Å; F218-P252 HydrophobicContact CB-CG 3.85Å; F218-P252 HydrophobicContact CD2-CB 4.48Å; F218-P252 HydrophobicContact CD2-CG 3.63Å; F218-P252 HydrophobicContact CE2-CG 4.43Å; F218-P252 HydrophobicContact CG-CG 3.88Å; F218-P287 HydrophobicContact CZ-CB 4.4Å
219	W	94.6	Very high	91.4	Very high	1 Å²	1	17.1 Å²	17.1	0%	0.004	9%	0.085	C	C	.	.	H	α-helix	trans	-69.6	-36.4	173.1	-87.1	103.8	0	0	0	112.7	I161 N164 L165 A215 N216 L221 V222 E223 L245 G248 W249	I161-W219 HydrophobicContact CD1-CZ3 4.28Å; I161-W219 HydrophobicContact CG2-CZ3 4.36Å; N164-W219 HydrophobicContact CB-CD2 3.88Å; N164-W219 HydrophobicContact CB-CE3 3.64Å; N164-W219 HydrophobicContact CB-CH2 3.24Å; N164-W219 HydrophobicContact CB-CZ2 3.5Å; N164-W219 VanDerWaalsContact CB-CZ2 3.5Å; N164-W219 HydrophobicContact CB-CZ3 3.3Å; N164-W219 VanDerWaalsContact CG-CH2 3.49Å; L165-W219 HydrophobicContact CD1-CB 3.73Å; A215-W219 WeakPolarHBondContact O-CB 3.44Å; A215-W219 PolarHBondContact O-N 3.02Å; N216-W219 PolarHBondContact O-N 3.48Å; W219-L221 VanDerWaalsContact C-N 3.27Å; W219-L221 PolarHBondContact O-N 3.35Å; W219-V222 HydrophobicContact CE3-CB 4.21Å; W219-V222 HydrophobicContact CE3-CG1 4.07Å; W219-V222 HydrophobicContact CZ3-CB 4.42Å; W219-V222 HydrophobicContact CZ3-CG1 3.82Å; W219-V222 PolarHBondContact O-N 3.02Å; W219-E223 WeakPolarHBondContact O-CB 3.34Å; W219-E223 PolarHBondContact O-N 3.17Å; W219-L245 HydrophobicContact CH2-CD1 4.1Å; W219-L245 HydrophobicContact CZ2-CD1 4.02Å; W219-G248 PolarHBondContact NE1-O 2.92Å; W219-W249 AromaticContact CE2-CD1 3.9Å; W219-W249 AromaticContact CE2-CE2 3.64Å; W219-W249 AromaticContact CE2-NE1 3.49Å; W219-W249 AromaticContact CZ2-CD1 3.4Å; W219-W249 VanDerWaalsContact CZ2-CD1 3.4Å; W219-W249 HydrophobicContact CZ2-CD2 4.41Å; W219-W249 AromaticContact CZ2-CE2 3.84Å; W219-W249 HydrophobicContact CZ2-CG 4.15Å; W219-W249 AromaticContact CZ2-NE1 3.16Å; W219-W249 AromaticContact NE1-CD1 3.78Å; W219-W249 AromaticContact NE1-CD2 3.29Å; W219-W249 VanDerWaalsContact NE1-CD2 3.29Å; W219-W249 AromaticContact NE1-CE2 3.05Å; W219-W249 AromaticContact NE1-CE3 3.8Å; W219-W249 AromaticContact NE1-CG 3.73Å; W219-W249 AromaticContact NE1-CH2 3.86Å; W219-W249 AromaticContact NE1-CZ2 3.35Å; W219-W249 AromaticContact NE1-NE1 3.39Å
220	L	91.8	Very high	91.1	Very high	2 Å²	2	20.3 Å²	20.3	1%	0.01	10%	0.101	C	C	.	.	H	α-helix	trans	-60.5	-39.6	168.6	-68.7	168.6	0	0	0	110.9	L165 F169 N216 F217 E223 G224 N295 L336	L165-L220 HydrophobicContact CD1-CD2 3.97Å; L165-L220 HydrophobicContact CD1-CG 4.28Å; F169-L220 HydrophobicContact CE2-CD2 3.94Å; F169-L220 HydrophobicContact CZ-CD1 4.38Å; F169-L220 HydrophobicContact CZ-CD2 3.84Å; F169-L220 HydrophobicContact CZ-CG 4.38Å; N216-L220 WeakPolarHBondContact O-CG 3.28Å; N216-L220 PolarHBondContact O-N 3.1Å; F217-L220 WeakPolarHBondContact O-CB 3.47Å; F217-L220 PolarHBondContact O-N 3.23Å; L220-E223 PolarHBondContact O-N 3.27Å; L220-G224 PolarHBondContact O-N 3.3Å; L220-G224 VanDerWaalsContact O-N 3.07Å; L220-N295 PolarHBondContact O-OD1 3.44Å; L220-L336 WeakPolarHBondContact CD2-O 3.03Å
221	L	92	Very high	90.6	Very high	15 Å²	15	19.6 Å²	19.6	8%	0.079	10%	0.099	C	C	.	.	H	α-helix	trans	-62.9	-46.7	173.6	178.6	65.4	0	0	0	113.2	F217 F218 W219 E223 G224 L225 V294 N295 L298	F217-L221 PolarHBondContact O-N 2.99Å; F218-L221 HydrophobicContact CD1-CD2 4.19Å; F218-L221 HydrophobicContact CE1-CD2 4.4Å; F218-L221 WeakPolarHBondContact O-CB 3.49Å; F218-L221 PolarHBondContact O-N 3.22Å; W219-L221 VanDerWaalsContact C-N 3.27Å; W219-L221 PolarHBondContact O-N 3.35Å; L221-E223 VanDerWaalsContact C-N 3.3Å; L221-E223 PolarHBondContact O-N 2.92Å; L221-G224 PolarHBondContact O-N 3.49Å; L221-L225 HydrophobicContact CD1-CD1 4.21Å; L221-L225 HydrophobicContact CD1-CG 4.17Å; L221-L225 HydrophobicContact CG-CD1 3.94Å; L221-L225 HydrophobicContact CG-CG 4.34Å; L221-L225 WeakPolarHBondContact O-CB 3.26Å; L221-L225 WeakPolarHBondContact O-CG 3.39Å; L221-L225 PolarHBondContact O-N 3.31Å; L221-V294 HydrophobicContact CD1-CB 4.04Å; L221-V294 HydrophobicContact CD1-CG1 3.61Å; L221-N295 WeakPolarHBondContact CA-ND2 3.44Å; L221-N295 WeakPolarHBondContact CA-OD1 3.11Å; L221-N295 PolarHBondContact N-ND2 3.13Å; L221-L298 HydrophobicContact CD1-CD1 3.91Å
222	V	92.8	Very high	90	Very high	0 Å²	0	22.2 Å²	22.2	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-60.9	-41.1	177.3	167.3	0	0	0	0	111.3	I161 F218 W219 L225 Y226 Y244 I247	I161-V222 HydrophobicContact CD1-CG1 4.32Å; I161-V222 HydrophobicContact CG2-CG1 4.35Å; F218-V222 WeakPolarHBondContact O-CG2 3.3Å; F218-V222 PolarHBondContact O-N 3.4Å; W219-V222 HydrophobicContact CE3-CB 4.21Å; W219-V222 HydrophobicContact CE3-CG1 4.07Å; W219-V222 HydrophobicContact CZ3-CB 4.42Å; W219-V222 HydrophobicContact CZ3-CG1 3.82Å; W219-V222 PolarHBondContact O-N 3.02Å; V222-L225 PolarHBondContact O-N 2.96Å; V222-Y226 VanDerWaalsContact O-CB 3.23Å; V222-Y226 WeakPolarHBondContact O-CB 3.1Å; V222-Y226 PolarHBondContact O-N 3.38Å; V222-Y244 HydrophobicContact CG1-CD1 4.08Å; V222-Y244 HydrophobicContact CG1-CG 4.07Å; V222-Y244 WeakPolarHBondContact CG2-O 3.25Å; V222-I247 HydrophobicContact CG2-CB 3.95Å; V222-I247 HydrophobicContact CG2-CG2 3.69Å
223	E	90.4	Very high	88.9	Confident	6 Å²	6	24.1 Å²	24.1	3%	0.028	13%	0.134	C	C	.	.	H	α-helix	trans	-60.4	-45.6	174.9	-177.6	75.2	-158	0	0	111.2	I161 H162 L165 W219 L220 L221 Y226 L227 Y375	I161-E223 WeakPolarHBondContact CG2-OE2 3.42Å; H162-E223 IonicContact CE1-OE1 2.89Å; H162-E223 PolarHBondContact CE1-OE1 3.31Å; H162-E223 IonicContact CE1-OE2 3.82Å; H162-E223 IonicContact ND1-OE1 3.38Å; H162-E223 PolarHBondContact ND1-OE1 2.87Å; H162-E223 VanDerWaalsContact ND1-OE1 3.11Å; H162-E223 IonicContact ND1-OE2 3.49Å; H162-E223 PolarHBondContact ND1-OE2 3.48Å; H162-E223 VanDerWaalsContact ND1-OE2 3.09Å; L165-E223 HydrophobicContact CD2-CB 4.36Å; L165-E223 HydrophobicContact CD2-CG 4.07Å; W219-E223 WeakPolarHBondContact O-CB 3.34Å; W219-E223 PolarHBondContact O-N 3.17Å; L220-E223 PolarHBondContact O-N 3.27Å; L221-E223 VanDerWaalsContact C-N 3.3Å; L221-E223 PolarHBondContact O-N 2.92Å; E223-Y226 PolarHBondContact O-N 2.9Å; E223-L227 WeakPolarHBondContact O-CB 3.43Å; E223-L227 PolarHBondContact O-N 2.91Å; E223-Y375 PolarHBondContact OE1-OH 2.91Å
224	G	89.3	Confident	87.8	Confident	0 Å²	0	30.6 Å²	30.6	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-63.9	-44.2	175.7	0	0	0	0	0	113.5	L220 L221 L227 H228 F337	L220-G224 PolarHBondContact O-N 3.3Å; L220-G224 VanDerWaalsContact O-N 3.07Å; L221-G224 PolarHBondContact O-N 3.49Å; G224-L227 PolarHBondContact O-N 3.37Å; G224-H228 VanDerWaalsContact O-CB 3.31Å; G224-H228 WeakPolarHBondContact O-CB 3.34Å; G224-H228 PolarHBondContact O-N 2.94Å; G224-F337 VanDerWaalsContact CA-CE1 3.45Å
225	L	90.5	Very high	86.5	Confident	45 Å²	45	35.3 Å²	35.3	24%	0.236	19%	0.19	C	C	.	.	H	α-helix	trans	-62.9	-45.2	176	-73.9	171.3	0	0	0	111.2	L221 V222 L227 H228 T229 Y244 L298	L221-L225 HydrophobicContact CD1-CD1 4.21Å; L221-L225 HydrophobicContact CD1-CG 4.17Å; L221-L225 HydrophobicContact CG-CD1 3.94Å; L221-L225 HydrophobicContact CG-CG 4.34Å; L221-L225 WeakPolarHBondContact O-CB 3.26Å; L221-L225 WeakPolarHBondContact O-CG 3.39Å; L221-L225 PolarHBondContact O-N 3.31Å; V222-L225 PolarHBondContact O-N 2.96Å; L225-L227 PolarHBondContact O-N 3.41Å; L225-H228 PolarHBondContact O-N 3.46Å; L225-T229 WeakPolarHBondContact O-CB 3.37Å; L225-T229 PolarHBondContact O-N 3.19Å; L225-T229 PolarHBondContact O-OG1 3.09Å; L225-Y244 HydrophobicContact CB-CE1 4.27Å; L225-L298 HydrophobicContact CD2-CD1 3.65Å; L225-L298 HydrophobicContact CD2-CD2 4.13Å; L225-L298 HydrophobicContact CG-CD1 3.81Å
226	Y	88.2	Confident	85.1	Confident	16 Å²	16	39 Å²	39	6%	0.063	22%	0.215	C	C	.	.	H	α-helix	trans	-59.6	-47.4	178	175	-105.1	0	0	0	111.5	R158 V222 E223 T229 L230 P237 Y244	R158-Y226 HydrophobicContact CB-CE1 4.16Å; R158-Y226 HydrophobicContact CG-CE1 4.14Å; V222-Y226 VanDerWaalsContact O-CB 3.23Å; V222-Y226 WeakPolarHBondContact O-CB 3.1Å; V222-Y226 PolarHBondContact O-N 3.38Å; E223-Y226 PolarHBondContact O-N 2.9Å; Y226-T229 PolarHBondContact O-N 2.93Å; Y226-L230 WeakPolarHBondContact O-CB 3.47Å; Y226-L230 PolarHBondContact O-N 2.91Å; Y226-P237 HydrophobicContact CE2-CB 4.36Å; Y226-Y244 AromaticContact CD2-CE2 3.94Å; Y226-Y244 HydrophobicContact CD2-CE2 3.94Å
227	L	86	Confident	83.6	Confident	46 Å²	46	41.6 Å²	41.6	24%	0.241	23%	0.231	C	C	.	.	H	α-helix	trans	-64.2	-42.1	178.6	-174.8	58.6	0	0	0	111.6	E223 G224 L225 L230 L231 I302 F337	E223-L227 WeakPolarHBondContact O-CB 3.43Å; E223-L227 PolarHBondContact O-N 2.91Å; G224-L227 PolarHBondContact O-N 3.37Å; L225-L227 PolarHBondContact O-N 3.41Å; L227-L230 PolarHBondContact O-N 3.31Å; L227-L231 HydrophobicContact CD1-CD1 4.46Å; L227-L231 HydrophobicContact CG-CD1 4.29Å; L227-L231 WeakPolarHBondContact O-CG 3.31Å; L227-L231 PolarHBondContact O-N 2.8Å; L227-L231 VanDerWaalsContact O-N 3.09Å; L227-I302 HydrophobicContact CB-CD1 4.21Å; L227-I302 HydrophobicContact CD2-CD1 4.04Å; L227-I302 HydrophobicContact CD2-CG2 4.14Å; L227-I302 HydrophobicContact CG-CD1 4.11Å; L227-F337 HydrophobicContact CD2-CZ 4.25Å
228	H	86	Confident	82.4	Confident	43 Å²	43	51.3 Å²	51.3	20%	0.199	27%	0.268	C	S	.	.	H	α-helix	trans	-64.6	-46.5	176.7	-175.4	-90.1	0	0	0	112.3	G224 L225 L230 L231 V232 L298 S301 I302	G224-H228 VanDerWaalsContact O-CB 3.31Å; G224-H228 WeakPolarHBondContact O-CB 3.34Å; G224-H228 PolarHBondContact O-N 2.94Å; L225-H228 PolarHBondContact O-N 3.46Å; H228-L230 VanDerWaalsContact C-N 3.31Å; H228-L230 PolarHBondContact O-N 3Å; H228-L231 PolarHBondContact O-N 2.94Å; H228-L231 VanDerWaalsContact O-N 3.15Å; H228-V232 PolarHBondContact O-N 3.41Å; H228-L298 HydrophobicContact CB-CD2 3.94Å; H228-S301 PolarHBondContact CD2-OG 2.95Å; H228-S301 VanDerWaalsContact CD2-OG 3.31Å; H228-S301 PolarHBondContact NE2-OG 3.25Å; H228-I302 HydrophobicContact CB-CD1 4.31Å; H228-I302 HydrophobicContact CB-CG1 4.27Å
229	T	85.9	Confident	81.2	Confident	38 Å²	38	61.5 Å²	61.5	23%	0.233	31%	0.306	C	S	.	.	H	α-helix	trans	-60.5	-40.9	176.7	-60.1	0	0	0	0	111.4	L225 Y226 L231 A233 L235 Y244	L225-T229 WeakPolarHBondContact O-CB 3.37Å; L225-T229 PolarHBondContact O-N 3.19Å; L225-T229 PolarHBondContact O-OG1 3.09Å; Y226-T229 PolarHBondContact O-N 2.93Å; T229-L231 VanDerWaalsContact C-N 3.3Å; T229-L231 PolarHBondContact O-N 3.41Å; T229-A233 HydrophobicContact CG2-CB 4.16Å; T229-A233 WeakPolarHBondContact O-CB 3.41Å; T229-A233 PolarHBondContact O-N 3.01Å; T229-L235 HydrophobicContact CG2-CB 4.42Å; T229-Y244 PolarHBondContact OG1-OH 2.87Å
230	L	83.6	Confident	80.5	Confident	76 Å²	76	63.3 Å²	63.3	40%	0.398	32%	0.318	S	S	.	.	H	α-helix	trans	-62.4	-37.5	176	-177.2	66.8	0	0	0	112.1	Y226 L227 H228	Y226-L230 WeakPolarHBondContact O-CB 3.47Å; Y226-L230 PolarHBondContact O-N 2.91Å; L227-L230 PolarHBondContact O-N 3.31Å; H228-L230 VanDerWaalsContact C-N 3.31Å; H228-L230 PolarHBondContact O-N 3Å
231	L	83	Confident	80.1	Confident	35 Å²	35	65.7 Å²	65.7	18%	0.183	33%	0.328	C	S	.	.	H	α-helix	trans	-77.7	-37.1	-178	-76.5	171.5	0	0	0	113.8	L227 H228 T229 I302 I305	L227-L231 HydrophobicContact CD1-CD1 4.46Å; L227-L231 HydrophobicContact CG-CD1 4.29Å; L227-L231 WeakPolarHBondContact O-CG 3.31Å; L227-L231 PolarHBondContact O-N 2.8Å; L227-L231 VanDerWaalsContact O-N 3.09Å; H228-L231 PolarHBondContact O-N 2.94Å; H228-L231 VanDerWaalsContact O-N 3.15Å; T229-L231 VanDerWaalsContact C-N 3.3Å; T229-L231 PolarHBondContact O-N 3.41Å; L231-I302 HydrophobicContact CD1-CB 4.41Å; L231-I302 HydrophobicContact CD1-CG1 4.18Å; L231-I302 HydrophobicContact CD1-CG2 3.91Å; L231-I305 HydrophobicContact CB-CD1 4.44Å; L231-I305 HydrophobicContact CB-CG2 4.27Å; L231-I305 HydrophobicContact CD2-CG2 4.4Å
232	V	82.2	Confident	79.8	Confident	86 Å²	86	70 Å²	70	52%	0.521	35%	0.351	S	S	.	.	H	α-helix	trans	-94.9	-45.9	-172.8	175.3	0	0	0	0	112.4	H228 I305	H228-V232 PolarHBondContact O-N 3.41Å; V232-I305 HydrophobicContact CG2-CD1 3.5Å; V232-I305 VanDerWaalsContact CG2-CD1 3.5Å
233	A	70.1	Confident	79.7	Confident	42 Å²	42	72.3 Å²	72.3	35%	0.347	37%	0.37	S	S	.	.			trans	-109.7	-5.5	-147.8	0	0	0	0	0	113.9	T229 L235	T229-A233 HydrophobicContact CG2-CB 4.16Å; T229-A233 WeakPolarHBondContact O-CB 3.41Å; T229-A233 PolarHBondContact O-N 3.01Å; A233-L235 HydrophobicContact CB-CD1 3.39Å; A233-L235 HydrophobicContact CB-CG 4.48Å; A233-L235 PolarHBondContact O-N 2.88Å
234	M	68.4	Low	79.7	Confident	170 Å²	170	73 Å²	73	84%	0.837	37%	0.372	S	S	*	.			trans	41.7	25.4	-177.4	-64.5	-64.6	-153	0	0	113.8
235	L	66.2	Low	79.8	Confident	99 Å²	99	74.3 Å²	74.3	52%	0.518	38%	0.38	S	S	.	.			trans	-77	141.4	-173.8	-94.8	124.5	0	0	0	109.3	T229 A233 P237	T229-L235 HydrophobicContact CG2-CB 4.42Å; A233-L235 HydrophobicContact CB-CD1 3.39Å; A233-L235 HydrophobicContact CB-CG 4.48Å; A233-L235 PolarHBondContact O-N 2.88Å; L235-P237 WeakPolarHBondContact O-CD 3.19Å
236	P	64.8	Low	79.9	Confident	80 Å²	80	77.3 Å²	77.3	52%	0.519	40%	0.395	S	S	.	.			trans	-62.3	113.3	178.8	21.5	-30.5	0	0	0	110.1	R238 R239	P236-R238 PolarHBondContact O-N 2.99Å; P236-R239 PolarHBondContact O-N 3.38Å
237	P	64.4	Low	80.1	Confident	54 Å²	54	79 Å²	79	35%	0.351	41%	0.405	S	S	.	.	H	α-helix	trans	-66.5	-15.2	-167.5	23.6	-33.6	0	0	0	113.8	Y226 L235 F241	Y226-P237 HydrophobicContact CE2-CB 4.36Å; L235-P237 WeakPolarHBondContact O-CD 3.19Å; P237-F241 PolarHBondContact O-N 3.45Å
238	R	65.3	Low	80.5	Confident	214 Å²	214	76.8 Å²	76.8	81%	0.808	39%	0.393	S	S	*	.	H	α-helix	trans	-69.2	-34.8	-175.4	-72.9	-170.7	172	178.9	-0.4	113.9	P236	P236-R238 PolarHBondContact O-N 2.99Å
239	R	68.8	Low	80.9	Confident	223 Å²	223	75.8 Å²	75.8	84%	0.842	39%	0.388	S	S	*	.	H	α-helix	trans	-75.8	-31.2	-179.5	-69.9	-170.8	-176.1	172.2	2.5	112.3	P236	P236-R239 PolarHBondContact O-N 3.38Å
240	C	79.8	Confident	81.3	Confident	39 Å²	39	75.2 Å²	75.2	26%	0.264	39%	0.389	S	S	.	.	H	α-helix	trans	-83.4	-12.2	-178.3	-59.3	0	0	0	0	113.6	L242 A243 Y244	C240-L242 VanDerWaalsContact C-N 3.33Å; C240-L242 PolarHBondContact O-N 2.91Å; C240-A243 WeakPolarHBondContact O-CB 3.03Å; C240-A243 PolarHBondContact O-N 3.28Å; C240-A243 VanDerWaalsContact O-N 3.07Å; C240-Y244 HydrophobicContact CB-CD2 4.22Å; C240-Y244 HydrophobicContact CB-CE2 3.66Å; C240-Y244 VanDerWaalsContact O-CD2 3.22Å; C240-Y244 WeakPolarHBondContact O-CD2 3.47Å; C240-Y244 PolarHBondContact O-N 3.33Å
241	F	83.6	Confident	81.8	Confident	53 Å²	53	75.2 Å²	75.2	23%	0.232	39%	0.389	C	S	.	.	H	α-helix	trans	-58.9	-40.9	-176.6	-174.4	-103.6	0	0	0	113.4	T157 I161 P237 A243 Y244 L245	T157-F241 HydrophobicContact CG2-CD2 3.84Å; T157-F241 HydrophobicContact CG2-CE2 4.43Å; I161-F241 HydrophobicContact CD1-CD2 3.83Å; I161-F241 HydrophobicContact CD1-CE2 3.61Å; I161-F241 HydrophobicContact CG1-CD2 4.48Å; I161-F241 HydrophobicContact CG1-CE2 4.2Å; P237-F241 PolarHBondContact O-N 3.45Å; F241-A243 VanDerWaalsContact C-N 3.35Å; F241-Y244 PolarHBondContact O-N 3.26Å; F241-L245 PolarHBondContact O-N 3.15Å
242	L	86.5	Confident	82.3	Confident	106 Å²	106	73.5 Å²	73.5	56%	0.555	38%	0.38	S	S	*	.	H	α-helix	trans	-65.5	-39.3	176.2	-176.9	63.9	0	0	0	111.7	C240 Y244 L245 L246	C240-L242 VanDerWaalsContact C-N 3.33Å; C240-L242 PolarHBondContact O-N 2.91Å; L242-Y244 VanDerWaalsContact C-N 3.35Å; L242-L245 PolarHBondContact O-N 2.88Å; L242-L246 HydrophobicContact CG-CD1 4.4Å; L242-L246 WeakPolarHBondContact O-CG 3.46Å; L242-L246 PolarHBondContact O-N 3.32Å
243	A	89.7	Confident	82.9	Confident	48 Å²	48	73 Å²	73	40%	0.397	38%	0.378	S	S	.	.	H	α-helix	trans	-62.8	-42.7	176.1	0	0	0	0	0	111.2	C240 F241 L245 L246 I247	C240-A243 WeakPolarHBondContact O-CB 3.03Å; C240-A243 PolarHBondContact O-N 3.28Å; C240-A243 VanDerWaalsContact O-N 3.07Å; F241-A243 VanDerWaalsContact C-N 3.35Å; A243-L245 VanDerWaalsContact C-N 3.33Å; A243-L245 PolarHBondContact O-N 2.93Å; A243-L246 PolarHBondContact O-N 2.78Å; A243-I247 VanDerWaalsContact O-CG1 3.27Å; A243-I247 WeakPolarHBondContact O-CG1 3.47Å; A243-I247 PolarHBondContact O-N 2.9Å
244	Y	91.4	Very high	84	Confident	19 Å²	19	75.8 Å²	75.8	8%	0.075	39%	0.39	C	S	.	.	H	α-helix	trans	-60.5	-40.5	174.1	-66.7	-44.1	0	0	0	112.6	I161 V222 L225 Y226 T229 C240 F241 L242 I247 G248	I161-Y244 HydrophobicContact CD1-CD2 4.47Å; V222-Y244 HydrophobicContact CG1-CD1 4.08Å; V222-Y244 HydrophobicContact CG1-CG 4.07Å; V222-Y244 WeakPolarHBondContact CG2-O 3.25Å; L225-Y244 HydrophobicContact CB-CE1 4.27Å; Y226-Y244 AromaticContact CD2-CE2 3.94Å; Y226-Y244 HydrophobicContact CD2-CE2 3.94Å; T229-Y244 PolarHBondContact OG1-OH 2.87Å; C240-Y244 HydrophobicContact CB-CD2 4.22Å; C240-Y244 HydrophobicContact CB-CE2 3.66Å; C240-Y244 VanDerWaalsContact O-CD2 3.22Å; C240-Y244 WeakPolarHBondContact O-CD2 3.47Å; C240-Y244 PolarHBondContact O-N 3.33Å; F241-Y244 PolarHBondContact O-N 3.26Å; L242-Y244 VanDerWaalsContact C-N 3.35Å; Y244-I247 PolarHBondContact O-N 2.96Å; Y244-G248 PolarHBondContact O-N 3.14Å
245	L	91.7	Very high	85.2	Confident	29 Å²	29	68.6 Å²	68.6	15%	0.152	36%	0.356	C	S	.	.	H	α-helix	trans	-65	-41	176.3	-168.4	74.1	0	0	0	112.3	L4 W219 F241 L242 A243 G248 W249	L4-L245 HydrophobicContact CD2-CD2 3.87Å; W219-L245 HydrophobicContact CH2-CD1 4.1Å; W219-L245 HydrophobicContact CZ2-CD1 4.02Å; F241-L245 PolarHBondContact O-N 3.15Å; L242-L245 PolarHBondContact O-N 2.88Å; A243-L245 VanDerWaalsContact C-N 3.33Å; A243-L245 PolarHBondContact O-N 2.93Å; L245-G248 PolarHBondContact O-N 3.39Å; L245-W249 PolarHBondContact O-N 2.93Å
246	L	92.3	Very high	86.5	Confident	107 Å²	107	64.3 Å²	64.3	56%	0.56	33%	0.334	S	S	*	.	I	π-helix	trans	-66.3	-38.3	176.4	-71.1	173.6	0	0	0	112	L242 A243 G250 L251	L242-L246 HydrophobicContact CG-CD1 4.4Å; L242-L246 WeakPolarHBondContact O-CG 3.46Å; L242-L246 PolarHBondContact O-N 3.32Å; A243-L246 PolarHBondContact O-N 2.78Å; L246-G250 CarbonylContact O-C 3.36Å; L246-G250 WeakPolarHBondContact O-CA 3.47Å; L246-G250 PolarHBondContact O-N 3.05Å; L246-L251 PolarHBondContact O-N 2.97Å
247	I	93.2	Very high	87.9	Confident	52 Å²	52	62.3 Å²	62.3	27%	0.267	33%	0.328	S	S	.	.	I	π-helix	trans	-67.5	-44.9	174.6	-65.7	164.3	0	0	0	110.3	F218 V222 A243 Y244 P252	F218-I247 HydrophobicContact CD1-CG2 4.31Å; V222-I247 HydrophobicContact CG2-CB 3.95Å; V222-I247 HydrophobicContact CG2-CG2 3.69Å; A243-I247 VanDerWaalsContact O-CG1 3.27Å; A243-I247 WeakPolarHBondContact O-CG1 3.47Å; A243-I247 PolarHBondContact O-N 2.9Å; Y244-I247 PolarHBondContact O-N 2.96Å; I247-P252 WeakPolarHBondContact O-CD 3.46Å
248	G	93.6	Very high	89.2	Confident	0 Å²	0	62.3 Å²	62.3	0%	0	33%	0.332	C	S	.	.	I	π-helix	trans	-70.7	-38.3	-174.6	0	0	0	0	0	115	W219 Y244 L245 P252	W219-G248 PolarHBondContact NE1-O 2.92Å; Y244-G248 PolarHBondContact O-N 3.14Å; L245-G248 PolarHBondContact O-N 3.39Å; G248-P252 VanDerWaalsContact O-CG 3.32Å; G248-P252 WeakPolarHBondContact O-CG 3.23Å
249	W	95.2	Very high	90.4	Very high	21 Å²	21	52.3 Å²	52.3	8%	0.08	30%	0.295	C	S	.	.	I	π-helix	trans	-113.3	-34.4	-179.4	-65	118.6	0	0	0	113.9	N164 L167 L171 Y211 A215 W219 L245 T253	N164-W249 PolarHBondContact OD1-NE1 3.33Å; L167-W249 HydrophobicContact CB-CZ2 4.48Å; L167-W249 HydrophobicContact CD2-CH2 4.37Å; L167-W249 HydrophobicContact CD2-CZ2 3.94Å; L167-W249 HydrophobicContact CG-CH2 4.24Å; L167-W249 HydrophobicContact CG-CZ2 4.19Å; L171-W249 HydrophobicContact CD1-CH2 3.74Å; L171-W249 HydrophobicContact CD1-CZ3 3.94Å; Y211-W249 HydrophobicContact CE1-CE3 4.33Å; Y211-W249 HydrophobicContact CE1-CZ3 4.39Å; Y211-W249 PolarHBondContact OH-O 3.21Å; A215-W249 HydrophobicContact CB-CE3 3.95Å; A215-W249 HydrophobicContact CB-CZ3 3.76Å; W219-W249 AromaticContact CE2-CD1 3.9Å; W219-W249 AromaticContact CE2-CE2 3.64Å; W219-W249 AromaticContact CE2-NE1 3.49Å; W219-W249 AromaticContact CZ2-CD1 3.4Å; W219-W249 VanDerWaalsContact CZ2-CD1 3.4Å; W219-W249 HydrophobicContact CZ2-CD2 4.41Å; W219-W249 AromaticContact CZ2-CE2 3.84Å; W219-W249 HydrophobicContact CZ2-CG 4.15Å; W219-W249 AromaticContact CZ2-NE1 3.16Å; W219-W249 AromaticContact NE1-CD1 3.78Å; W219-W249 AromaticContact NE1-CD2 3.29Å; W219-W249 VanDerWaalsContact NE1-CD2 3.29Å; W219-W249 AromaticContact NE1-CE2 3.05Å; W219-W249 AromaticContact NE1-CE3 3.8Å; W219-W249 AromaticContact NE1-CG 3.73Å; W219-W249 AromaticContact NE1-CH2 3.86Å; W219-W249 AromaticContact NE1-CZ2 3.35Å; W219-W249 AromaticContact NE1-NE1 3.39Å; L245-W249 PolarHBondContact O-N 2.93Å; W249-T253 PolarHBondContact O-N 3.29Å; W249-T253 PolarHBondContact O-OG1 3.17Å
250	G	93.6	Very high	91.4	Very high	26 Å²	26	43.1 Å²	43.1	27%	0.268	26%	0.263	S	S	.	.	I	π-helix	trans	-73.5	-50.8	-174.6	0	0	0	0	0	112.6	L246 T253 V254	L246-G250 CarbonylContact O-C 3.36Å; L246-G250 WeakPolarHBondContact O-CA 3.47Å; L246-G250 PolarHBondContact O-N 3.05Å; G250-T253 WeakPolarHBondContact O-CA 3.37Å; G250-T253 VanDerWaalsContact O-CB 3.26Å; G250-T253 WeakPolarHBondContact O-CB 3.23Å; G250-T253 PolarHBondContact O-N 3.32Å; G250-V254 PolarHBondContact O-N 3.37Å; G250-V254 VanDerWaalsContact O-N 3.09Å
251	L	93	Very high	91.9	Very high	76 Å²	76	43 Å²	43	40%	0.398	27%	0.266	S	S	.	.	H	α-helix	trans	-60.5	-43.2	-179.9	-173.1	53.5	0	0	0	113.2	F218 L246 T253 V254 C255	F218-L251 HydrophobicContact CD1-CB 4.42Å; F218-L251 HydrophobicContact CD1-CD2 3.97Å; F218-L251 HydrophobicContact CD1-CG 4.33Å; F218-L251 HydrophobicContact CE1-CB 4.24Å; F218-L251 HydrophobicContact CE1-CD2 3.21Å; F218-L251 HydrophobicContact CE1-CG 3.66Å; F218-L251 HydrophobicContact CZ-CD2 3.72Å; F218-L251 HydrophobicContact CZ-CG 3.75Å; L246-L251 PolarHBondContact O-N 2.97Å; L251-T253 VanDerWaalsContact C-N 3.27Å; L251-T253 PolarHBondContact O-N 3.17Å; L251-V254 PolarHBondContact O-N 3.46Å; L251-C255 PolarHBondContact O-N 3.29Å; L251-C255 PolarHBondContact O-SG 2.72Å; L251-C255 VanDerWaalsContact O-SG 3.41Å
252	P	95	Very high	92.1	Very high	0 Å²	0	41.5 Å²	41.5	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-54.5	-40.2	168.8	-26	30.8	0	0	0	113.9	Y211 M214 A215 F218 I247 G248 V254 C255 I256	Y211-P252 HydrophobicContact CD2-CB 4.16Å; Y211-P252 HydrophobicContact CE2-CB 3.89Å; M214-P252 HydrophobicContact CB-CB 4.16Å; M214-P252 HydrophobicContact CG-CB 3.73Å; M214-P252 HydrophobicContact CG-CG 4.3Å; A215-P252 HydrophobicContact CB-CB 4.23Å; A215-P252 HydrophobicContact CB-CG 4.14Å; F218-P252 HydrophobicContact CB-CG 3.85Å; F218-P252 HydrophobicContact CD2-CB 4.48Å; F218-P252 HydrophobicContact CD2-CG 3.63Å; F218-P252 HydrophobicContact CE2-CG 4.43Å; F218-P252 HydrophobicContact CG-CG 3.88Å; I247-P252 WeakPolarHBondContact O-CD 3.46Å; G248-P252 VanDerWaalsContact O-CG 3.32Å; G248-P252 WeakPolarHBondContact O-CG 3.23Å; P252-V254 VanDerWaalsContact C-N 3.33Å; P252-V254 PolarHBondContact O-N 2.02Å; P252-C255 PolarHBondContact O-N 2.96Å; P252-I256 WeakPolarHBondContact O-CB 3.47Å; P252-I256 WeakPolarHBondContact O-CG1 3.31Å; P252-I256 PolarHBondContact O-N 2.82Å
253	T	93.8	Very high	92	Very high	75 Å²	75	36.6 Å²	36.6	46%	0.46	24%	0.237	S	C	.	.	H	α-helix	trans	-62.9	-42.4	179.6	-52.9	0	0	0	0	110.9	Y211 W249 G250 L251 G257	Y211-T253 WeakPolarHBondContact CE2-OG1 3.25Å; W249-T253 PolarHBondContact O-N 3.29Å; W249-T253 PolarHBondContact O-OG1 3.17Å; G250-T253 WeakPolarHBondContact O-CA 3.37Å; G250-T253 VanDerWaalsContact O-CB 3.26Å; G250-T253 WeakPolarHBondContact O-CB 3.23Å; G250-T253 PolarHBondContact O-N 3.32Å; L251-T253 VanDerWaalsContact C-N 3.27Å; L251-T253 PolarHBondContact O-N 3.17Å; T253-G257 PolarHBondContact O-N 2.92Å
254	V	94.2	Very high	91.8	Very high	101 Å²	101	38.7 Å²	38.7	61%	0.612	24%	0.241	S	C	*	.	H	α-helix	trans	-66.4	-46.9	177.9	177.8	0	0	0	0	111.2	G250 L251 P252 I256 G257 A258	G250-V254 PolarHBondContact O-N 3.37Å; G250-V254 VanDerWaalsContact O-N 3.09Å; L251-V254 PolarHBondContact O-N 3.46Å; P252-V254 VanDerWaalsContact C-N 3.33Å; P252-V254 PolarHBondContact O-N 2.02Å; V254-I256 PolarHBondContact O-N 2.94Å; V254-G257 PolarHBondContact O-N 3.42Å; V254-A258 PolarHBondContact O-N 3.44Å
255	C	94	Very high	91.5	Very high	19 Å²	19	47.5 Å²	47.5	13%	0.128	28%	0.275	C	S	.	.	H	α-helix	trans	-62.4	-42.4	179.2	-66.2	0	0	0	0	112.2	M214 L251 P252 A258 W259 P287	M214-C255 HydrophobicContact CE-CB 3.92Å; M214-C255 HydrophobicContact SD-CB 4.42Å; L251-C255 PolarHBondContact O-N 3.29Å; L251-C255 PolarHBondContact O-SG 2.72Å; L251-C255 VanDerWaalsContact O-SG 3.41Å; P252-C255 PolarHBondContact O-N 2.96Å; C255-A258 PolarHBondContact O-N 3.39Å; C255-W259 PolarHBondContact O-N 2.91Å; C255-P287 HydrophobicContact CB-CG 4.38Å
256	I	93.4	Very high	90.9	Very high	8 Å²	8	50.6 Å²	50.6	4%	0.041	29%	0.291	C	S	.	.	H	α-helix	trans	-71.3	-35.9	178.2	-64.8	-65.5	0	0	0	111.6	V207 Q210 Y211 M214 P252 V254 W259 T260 I284	V207-I256 HydrophobicContact CG1-CG2 3.84Å; Q210-I256 HydrophobicContact CB-CD1 3.72Å; Y211-I256 HydrophobicContact CD2-CG1 4.21Å; M214-I256 HydrophobicContact CB-CD1 4.37Å; M214-I256 HydrophobicContact CB-CG1 4.43Å; M214-I256 HydrophobicContact CE-CD1 3.89Å; M214-I256 HydrophobicContact CE-CG1 4.43Å; P252-I256 WeakPolarHBondContact O-CB 3.47Å; P252-I256 WeakPolarHBondContact O-CG1 3.31Å; P252-I256 PolarHBondContact O-N 2.82Å; V254-I256 PolarHBondContact O-N 2.94Å; I256-W259 PolarHBondContact O-N 3.28Å; I256-T260 VanDerWaalsContact O-CB 3.3Å; I256-T260 WeakPolarHBondContact O-CB 3.39Å; I256-T260 PolarHBondContact O-N 3.36Å; I256-T260 PolarHBondContact O-OG1 2.92Å; I256-I284 HydrophobicContact CD1-CD1 4.33Å; I256-I284 HydrophobicContact CD1-CG1 4.49Å
257	G	92.5	Very high	89.9	Confident	39 Å²	39	46.6 Å²	46.6	40%	0.402	27%	0.27	S	S	.	.	H	α-helix	trans	-59.6	-46	171.9	0	0	0	0	0	111.9	T253 V254 T260 A261	T253-G257 PolarHBondContact O-N 2.92Å; V254-G257 PolarHBondContact O-N 3.42Å; G257-T260 PolarHBondContact O-N 3.25Å; G257-A261 WeakPolarHBondContact O-CB 3.2Å; G257-A261 PolarHBondContact O-N 3.19Å
258	A	91.8	Very high	89	Confident	53 Å²	53	48 Å²	48	44%	0.438	28%	0.278	S	S	.	.	H	α-helix	trans	-62.9	-41.9	175.8	0	0	0	0	0	112.4	V254 C255 A261 A262	V254-A258 PolarHBondContact O-N 3.44Å; C255-A258 PolarHBondContact O-N 3.39Å; A258-A261 PolarHBondContact O-N 3.21Å; A258-A262 WeakPolarHBondContact O-CB 3.3Å; A258-A262 PolarHBondContact O-N 3.39Å
259	W	91.7	Very high	87.8	Confident	4 Å²	4	53 Å²	53	2%	0.015	31%	0.309	C	S	.	.	H	α-helix	trans	-63.5	-46.1	174.9	175.3	74.7	0	0	0	112.7	V207 Q210 C255 I256 A261 A262 R263 W272 P280 V283 I284	V207-W259 HydrophobicContact CG2-CZ3 3.84Å; Q210-W259 HydrophobicContact CG-CH2 4.11Å; Q210-W259 HydrophobicContact CG-CZ3 4.32Å; C255-W259 PolarHBondContact O-N 2.91Å; I256-W259 PolarHBondContact O-N 3.28Å; W259-A261 VanDerWaalsContact C-N 3.31Å; W259-A261 PolarHBondContact O-N 3.3Å; W259-A262 WeakPolarHBondContact O-CB 3.27Å; W259-A262 PolarHBondContact O-N 2.99Å; W259-A262 VanDerWaalsContact O-N 3.14Å; W259-R263 HydrophobicContact CD2-CG 4.03Å; W259-R263 HydrophobicContact CH2-CG 4.35Å; W259-R263 HydrophobicContact CZ2-CG 3.8Å; W259-R263 WeakPolarHBondContact O-CG 3.4Å; W259-R263 PolarHBondContact O-N 2.93Å; W259-W272 AromaticContact CH2-CE3 3.82Å; W259-W272 HydrophobicContact CH2-CE3 3.82Å; W259-W272 HydrophobicContact CH2-CZ3 4.5Å; W259-W272 AromaticContact CZ3-CE3 3.93Å; W259-W272 HydrophobicContact CZ3-CE3 3.93Å; W259-W272 HydrophobicContact CZ3-CZ3 4.17Å; W259-P280 PolarHBondContact NE1-O 3.01Å; W259-V283 HydrophobicContact CB-CG1 4.06Å; W259-I284 HydrophobicContact CB-CD1 4.17Å; W259-I284 HydrophobicContact CB-CG1 3.84Å; W259-I284 VanDerWaalsContact CD1-CD1 3.46Å; W259-I284 VanDerWaalsContact CD1-CG1 3.44Å; W259-I284 HydrophobicContact CD2-CD1 3.33Å; W259-I284 HydrophobicContact CD2-CG1 4Å; W259-I284 HydrophobicContact CE3-CD1 3.99Å; W259-I284 HydrophobicContact CG-CD1 3.39Å; W259-I284 HydrophobicContact CG-CG1 3.47Å; W259-I284 VanDerWaalsContact CG-CG1 3.47Å; W259-I284 HydrophobicContact CZ2-CD1 3.93Å
260	T	90.1	Very high	86.5	Confident	30 Å²	30	53.2 Å²	53.2	18%	0.184	32%	0.317	C	S	.	.	H	α-helix	trans	-60.1	-44	178.9	-57.3	0	0	0	0	110.1	V207 I256 G257 R263 L264 W272	V207-T260 HydrophobicContact CG2-CG2 4.48Å; I256-T260 VanDerWaalsContact O-CB 3.3Å; I256-T260 WeakPolarHBondContact O-CB 3.39Å; I256-T260 PolarHBondContact O-N 3.36Å; I256-T260 PolarHBondContact O-OG1 2.92Å; G257-T260 PolarHBondContact O-N 3.25Å; T260-R263 PolarHBondContact O-N 2.88Å; T260-L264 HydrophobicContact CG2-CD1 4.17Å; T260-L264 VanDerWaalsContact O-CG 3.31Å; T260-L264 WeakPolarHBondContact O-CG 3.38Å; T260-L264 PolarHBondContact O-N 3.04Å; T260-W272 HydrophobicContact CG2-CH2 3.84Å; T260-W272 HydrophobicContact CG2-CZ3 3.93Å
261	A	89.3	Confident	85.4	Confident	38 Å²	38	53.1 Å²	53.1	31%	0.314	31%	0.312	S	S	.	.	H	α-helix	trans	-61	-47.2	173.6	0	0	0	0	0	111.6	G257 A258 W259 R263 L264 Y265	G257-A261 WeakPolarHBondContact O-CB 3.2Å; G257-A261 PolarHBondContact O-N 3.19Å; A258-A261 PolarHBondContact O-N 3.21Å; W259-A261 VanDerWaalsContact C-N 3.31Å; W259-A261 PolarHBondContact O-N 3.3Å; A261-R263 VanDerWaalsContact C-N 3.3Å; A261-R263 PolarHBondContact O-N 3.35Å; A261-L264 PolarHBondContact O-N 3.43Å; A261-Y265 HydrophobicContact CB-CD2 4.4Å; A261-Y265 HydrophobicContact CB-CE2 4.31Å; A261-Y265 WeakPolarHBondContact O-CD2 3.32Å; A261-Y265 PolarHBondContact O-N 3.45Å
262	A	87.5	Confident	84.6	Confident	20 Å²	20	50.1 Å²	50.1	17%	0.165	30%	0.295	C	S	.	.	H	α-helix	trans	-59.3	-39.4	177.9	0	0	0	0	0	112.5	A258 W259 L266	A258-A262 WeakPolarHBondContact O-CB 3.3Å; A258-A262 PolarHBondContact O-N 3.39Å; W259-A262 WeakPolarHBondContact O-CB 3.27Å; W259-A262 PolarHBondContact O-N 2.99Å; W259-A262 VanDerWaalsContact O-N 3.14Å; A262-L266 VanDerWaalsContact O-CB 3.3Å; A262-L266 WeakPolarHBondContact O-CB 3.31Å; A262-L266 WeakPolarHBondContact O-CG 3.45Å; A262-L266 PolarHBondContact O-N 3.35Å
263	R	85.8	Confident	83.4	Confident	3 Å²	3	54.3 Å²	54.3	1%	0.011	32%	0.318	C	S	.	.	H	α-helix	trans	-64.6	-47.9	173.9	-68.2	-64.7	-72.4	-123.9	17.4	111.5	W259 T260 A261 Y265 L266 E267 W272 T274 N275 P280	W259-R263 HydrophobicContact CD2-CG 4.03Å; W259-R263 HydrophobicContact CH2-CG 4.35Å; W259-R263 HydrophobicContact CZ2-CG 3.8Å; W259-R263 WeakPolarHBondContact O-CG 3.4Å; W259-R263 PolarHBondContact O-N 2.93Å; T260-R263 PolarHBondContact O-N 2.88Å; A261-R263 VanDerWaalsContact C-N 3.3Å; A261-R263 PolarHBondContact O-N 3.35Å; R263-Y265 VanDerWaalsContact C-N 3.29Å; R263-Y265 PolarHBondContact O-N 3.07Å; R263-L266 PolarHBondContact O-N 3.4Å; R263-E267 CarbonylContact O-C 3.53Å; R263-E267 WeakPolarHBondContact O-CA 3.14Å; R263-E267 PolarHBondContact O-N 2.87Å; R263-W272 HydrophobicContact CB-CD2 3.92Å; R263-W272 HydrophobicContact CB-CE3 4.14Å; R263-W272 HydrophobicContact CB-CH2 3.89Å; R263-W272 HydrophobicContact CB-CZ2 3.63Å; R263-W272 HydrophobicContact CB-CZ3 4.12Å; R263-W272 HydrophobicContact CG-CD2 4.18Å; R263-W272 HydrophobicContact CG-CE3 4.25Å; R263-W272 VanDerWaalsContact NH2-CA 3.27Å; R263-T274 PolarHBondContact NH2-O 3.45Å; R263-N275 PolarHBondContact NH1-OD1 2.91Å; R263-P280 HydrophobicContact CG-CB 4.14Å
264	L	85.7	Confident	82.1	Confident	92 Å²	92	53.3 Å²	53.3	48%	0.482	31%	0.312	S	S	.	.	H	α-helix	trans	-60.4	-36.1	179	-71	167.4	0	0	0	113.3	T260 A261 W272	T260-L264 HydrophobicContact CG2-CD1 4.17Å; T260-L264 VanDerWaalsContact O-CG 3.31Å; T260-L264 WeakPolarHBondContact O-CG 3.38Å; T260-L264 PolarHBondContact O-N 3.04Å; A261-L264 PolarHBondContact O-N 3.43Å; L264-W272 HydrophobicContact CD2-CH2 4Å; L264-W272 HydrophobicContact CD2-CZ2 3.74Å; L264-W272 HydrophobicContact CG-CH2 3.88Å; L264-W272 HydrophobicContact CG-CZ2 3.9Å
265	Y	84.6	Confident	80.8	Confident	205 Å²	205	51.7 Å²	51.7	80%	0.804	30%	0.299	S	S	*	.	H	α-helix	trans	-82.8	-31.3	-178.8	-74.6	-63.8	0	0	0	114.3	A261 R263	A261-Y265 HydrophobicContact CB-CD2 4.4Å; A261-Y265 HydrophobicContact CB-CE2 4.31Å; A261-Y265 WeakPolarHBondContact O-CD2 3.32Å; A261-Y265 PolarHBondContact O-N 3.45Å; R263-Y265 VanDerWaalsContact C-N 3.29Å; R263-Y265 PolarHBondContact O-N 3.07Å
266	L	78.4	Confident	79.3	Confident	93 Å²	93	56 Å²	56	49%	0.487	32%	0.321	S	S	.	.	H	α-helix	trans	-100.2	-40.7	-174.1	-63	173.2	0	0	0	112.7	A262 R263 V279 P280	A262-L266 VanDerWaalsContact O-CB 3.3Å; A262-L266 WeakPolarHBondContact O-CB 3.31Å; A262-L266 WeakPolarHBondContact O-CG 3.45Å; A262-L266 PolarHBondContact O-N 3.35Å; R263-L266 PolarHBondContact O-N 3.4Å; L266-V279 HydrophobicContact CD1-CB 4.19Å; L266-V279 HydrophobicContact CD1-CG1 3.99Å; L266-P280 HydrophobicContact CD1-CG 4.21Å
267	E	70.7	Confident	78.1	Confident	23 Å²	23	60.3 Å²	60.3	11%	0.107	34%	0.341	C	S	.	.			trans	-153	87.9	-173	-66.2	-179.5	149	0	0	111.2	R263 T269 W272 H277	R263-E267 CarbonylContact O-C 3.53Å; R263-E267 WeakPolarHBondContact O-CA 3.14Å; R263-E267 PolarHBondContact O-N 2.87Å; E267-T269 VanDerWaalsContact C-N 3.28Å; E267-W272 PolarHBondContact O-NE1 3.33Å; E267-H277 VanDerWaalsContact CG-CD2 3.45Å; E267-H277 WeakPolarHBondContact CG-CD2 3.46Å; E267-H277 WeakPolarHBondContact OE1-CB 3.41Å; E267-H277 IonicContact OE1-CD2 2.76Å; E267-H277 PolarHBondContact OE1-CD2 3.35Å; E267-H277 IonicContact OE1-CE1 3.45Å; E267-H277 IonicContact OE1-CG 2.71Å; E267-H277 PolarHBondContact OE1-N 3.46Å; E267-H277 IonicContact OE1-ND1 2.76Å; E267-H277 PolarHBondContact OE1-ND1 3.42Å; E267-H277 IonicContact OE1-NE2 3.49Å; E267-H277 PolarHBondContact OE1-NE2 3.47Å
268	D	75.1	Confident	77.3	Confident	82 Å²	82	62 Å²	62	44%	0.439	35%	0.347	S	S	.	.			trans	-92.8	22	172.2	-160.6	35.3	0	0	0	113.7	K203	K203-D268 PolarHBondContact NZ-O 3.47Å; K203-D268 VanDerWaalsContact NZ-O 3.1Å; K203-D268 IonicContact NZ-OD1 3.63Å; K203-D268 PolarHBondContact NZ-OD1 2.92Å; K203-D268 IonicContact NZ-OD2 3.09Å; K203-D268 PolarHBondContact NZ-OD2 3.31Å
269	T	68.5	Low	76.7	Confident	106 Å²	106	63.4 Å²	63.4	65%	0.65	35%	0.35	S	S	*	.			trans	-89.1	148.9	175.7	55.9	0	0	0	0	110.6	E267	E267-T269 VanDerWaalsContact C-N 3.28Å
270	G	67.4	Low	76.1	Confident	24 Å²	24	63.2 Å²	63.2	25%	0.247	35%	0.349	C	S	.	.	S	Bend	trans	79.3	178.5	174.4	0	0	0	0	0	115	W199 K203	W199-G270 VanDerWaalsContact CZ3-C 3.45Å; W199-G270 VanDerWaalsContact CZ3-N 3.31Å; K203-G270 WeakPolarHBondContact CE-O 3.37Å
271	C	71.1	Confident	75.7	Confident	24 Å²	24	66.4 Å²	66.4	16%	0.162	36%	0.358	C	S	.	.			trans	-74.1	141.2	142	-171.1	0	0	0	0	108.2	C202 L206 D273	C202-C271 VanDerWaalsContact C-SG 3.59Å; C202-C271 HydrophobicContact CB-CB 3.84Å; C202-C271 WeakPolarHBondContact CB-SG 3.27Å; C202-C271 WeakPolarHBondContact SG-CB 3.38Å; C202-C271 CovalentContact SG-SG 2.02Å; C202-C271 PolarHBondContact SG-SG 3.08Å; L206-C271 WeakPolarHBondContact CD1-SG 3.12Å; C271-D273 PolarHBondContact O-N 2.98Å
272	W	75.1	Confident	75.5	Confident	14 Å²	14	70.3 Å²	70.3	5%	0.053	37%	0.365	C	S	.	.	T	Hydrogen-bonded Turn	trans	-71.2	33.4	-175	-68.1	-18.7	0	0	0	115.2	K203 L206 V207 W259 T260 R263 L264 E267	K203-W272 HydrophobicContact CD-CZ2 4.41Å; K203-W272 HydrophobicContact CG-CD2 4.19Å; K203-W272 HydrophobicContact CG-CG 4.33Å; L206-W272 HydrophobicContact CD1-CB 4.06Å; V207-W272 HydrophobicContact CG2-CE3 3.93Å; V207-W272 HydrophobicContact CG2-CZ3 3.52Å; W259-W272 AromaticContact CH2-CE3 3.82Å; W259-W272 HydrophobicContact CH2-CE3 3.82Å; W259-W272 HydrophobicContact CH2-CZ3 4.5Å; W259-W272 AromaticContact CZ3-CE3 3.93Å; W259-W272 HydrophobicContact CZ3-CE3 3.93Å; W259-W272 HydrophobicContact CZ3-CZ3 4.17Å; T260-W272 HydrophobicContact CG2-CH2 3.84Å; T260-W272 HydrophobicContact CG2-CZ3 3.93Å; R263-W272 HydrophobicContact CB-CD2 3.92Å; R263-W272 HydrophobicContact CB-CE3 4.14Å; R263-W272 HydrophobicContact CB-CH2 3.89Å; R263-W272 HydrophobicContact CB-CZ2 3.63Å; R263-W272 HydrophobicContact CB-CZ3 4.12Å; R263-W272 HydrophobicContact CG-CD2 4.18Å; R263-W272 HydrophobicContact CG-CE3 4.25Å; R263-W272 VanDerWaalsContact NH2-CA 3.27Å; L264-W272 HydrophobicContact CD2-CH2 4Å; L264-W272 HydrophobicContact CD2-CZ2 3.74Å; L264-W272 HydrophobicContact CG-CH2 3.88Å; L264-W272 HydrophobicContact CG-CZ2 3.9Å; E267-W272 PolarHBondContact O-NE1 3.33Å
273	D	70.6	Confident	75.5	Confident	88 Å²	88	71.7 Å²	71.7	47%	0.471	37%	0.371	S	S	.	.	T	Hydrogen-bonded Turn	trans	-81.1	-31.4	-177.7	-164.4	42.5	0	0	0	112	L206 C271	L206-D273 HydrophobicContact CD1-CB 4.14Å; C271-D273 PolarHBondContact O-N 2.98Å
274	T	65.9	Low	75.5	Confident	54 Å²	54	72.3 Å²	72.3	33%	0.331	37%	0.374	S	S	.	.			trans	-97.2	147.2	174.2	60.9	0	0	0	0	111.8	R26 R263	R26-T274 VanDerWaalsContact NH1-CG2 3.26Å; R26-T274 PolarHBondContact NH1-OG1 3.38Å; R263-T274 PolarHBondContact NH2-O 3.45Å
275	N	67.2	Low	75.5	Confident	66 Å²	66	72.3 Å²	72.3	35%	0.353	37%	0.368	S	S	.	.			trans	-120.3	85.4	178.9	-68.3	11.4	0	0	0	108.3	R263 W281	R263-N275 PolarHBondContact NH1-OD1 2.91Å; N275-W281 HydrophobicContact CB-CB 4.43Å; N275-W281 WeakPolarHBondContact ND2-CB 3.36Å
276	D	62.5	Low	75.7	Confident	111 Å²	111	66.5 Å²	66.5	59%	0.594	35%	0.349	S	S	*	.			trans	-76.1	-35.6	179.4	-65.1	-17.8	0	0	0	110
277	H	67.8	Low	76.4	Confident	97 Å²	97	63.2 Å²	63.2	45%	0.449	33%	0.334	S	S	.	.	S	Bend	trans	-90.8	136.6	168.7	-69.7	-20	0	0	0	113.7	E267 V279 P280	E267-H277 VanDerWaalsContact CG-CD2 3.45Å; E267-H277 WeakPolarHBondContact CG-CD2 3.46Å; E267-H277 WeakPolarHBondContact OE1-CB 3.41Å; E267-H277 IonicContact OE1-CD2 2.76Å; E267-H277 PolarHBondContact OE1-CD2 3.35Å; E267-H277 IonicContact OE1-CE1 3.45Å; E267-H277 IonicContact OE1-CG 2.71Å; E267-H277 PolarHBondContact OE1-N 3.46Å; E267-H277 IonicContact OE1-ND1 2.76Å; E267-H277 PolarHBondContact OE1-ND1 3.42Å; E267-H277 IonicContact OE1-NE2 3.49Å; E267-H277 PolarHBondContact OE1-NE2 3.47Å; H277-V279 VanDerWaalsContact C-N 3.31Å; H277-V279 PolarHBondContact O-N 2.94Å; H277-P280 WeakPolarHBondContact O-CD 3.03Å
278	S	75.5	Confident	77.2	Confident	76 Å²	76	63.2 Å²	63.2	53%	0.531	34%	0.335	S	S	.	.	H	α-helix	trans	-69.9	-27	178.3	60.2	0	0	0	0	113	W281 W282	S278-W281 WeakPolarHBondContact O-CB 3.06Å; S278-W281 PolarHBondContact O-N 3.44Å; S278-W282 PolarHBondContact O-N 3.34Å; S278-W282 VanDerWaalsContact O-N 3.11Å
279	V	80	Confident	77.8	Confident	82 Å²	82	61.4 Å²	61.4	50%	0.497	33%	0.325	S	S	.	.	H	α-helix	trans	-63.4	-56	-172.1	177.4	0	0	0	0	112.5	L266 H277 W281 W282 V283	L266-V279 HydrophobicContact CD1-CB 4.19Å; L266-V279 HydrophobicContact CD1-CG1 3.99Å; H277-V279 VanDerWaalsContact C-N 3.31Å; H277-V279 PolarHBondContact O-N 2.94Å; V279-W281 PolarHBondContact O-N 2.71Å; V279-W282 PolarHBondContact O-N 2.81Å; V279-W282 VanDerWaalsContact O-N 3.16Å; V279-V283 WeakPolarHBondContact O-CG2 3.47Å; V279-V283 PolarHBondContact O-N 3.47Å
280	P	79.3	Confident	78.8	Confident	0 Å²	0	61 Å²	61	0%	0	32%	0.317	C	S	.	.	H	α-helix	trans	-60	-31.9	179.4	-21.9	33.3	0	0	0	112.7	W259 R263 L266 H277 V283	W259-P280 PolarHBondContact NE1-O 3.01Å; R263-P280 HydrophobicContact CG-CB 4.14Å; L266-P280 HydrophobicContact CD1-CG 4.21Å; H277-P280 WeakPolarHBondContact O-CD 3.03Å; P280-V283 PolarHBondContact O-N 3.48Å
281	W	81.6	Confident	80	Confident	96 Å²	96	59.9 Å²	59.9	36%	0.364	31%	0.306	S	S	.	.	H	α-helix	trans	-66.3	-42.8	177.8	-178	78.7	0	0	0	112.8	N275 S278 V279 V283 I284 R285	N275-W281 HydrophobicContact CB-CB 4.43Å; N275-W281 WeakPolarHBondContact ND2-CB 3.36Å; S278-W281 WeakPolarHBondContact O-CB 3.06Å; S278-W281 PolarHBondContact O-N 3.44Å; V279-W281 PolarHBondContact O-N 2.71Å; W281-V283 VanDerWaalsContact C-N 3.3Å; W281-V283 PolarHBondContact O-N 3.33Å; W281-I284 PolarHBondContact O-N 2.96Å; W281-R285 WeakPolarHBondContact O-CB 3.27Å; W281-R285 PolarHBondContact O-N 2.95Å
282	W	85.3	Confident	80.7	Confident	121 Å²	121	59.2 Å²	59.2	46%	0.458	30%	0.301	S	S	.	.	H	α-helix	trans	-65.5	-32.1	176.4	-78.8	110.2	0	0	0	112.8	S278 V279 I284 R285 I286	S278-W282 PolarHBondContact O-N 3.34Å; S278-W282 VanDerWaalsContact O-N 3.11Å; V279-W282 PolarHBondContact O-N 2.81Å; V279-W282 VanDerWaalsContact O-N 3.16Å; W282-I284 VanDerWaalsContact C-N 3.3Å; W282-I284 PolarHBondContact O-N 3.42Å; W282-R285 PolarHBondContact O-N 2.98Å; W282-I286 HydrophobicContact CB-CD1 4.24Å; W282-I286 HydrophobicContact CE3-CD1 4.33Å; W282-I286 HydrophobicContact CE3-CG1 3.95Å; W282-I286 WeakPolarHBondContact O-CB 3.46Å; W282-I286 VanDerWaalsContact O-CG1 3.24Å; W282-I286 WeakPolarHBondContact O-CG1 3.25Å; W282-I286 PolarHBondContact O-N 2.95Å
283	V	87.6	Confident	81.4	Confident	48 Å²	48	62.8 Å²	62.8	29%	0.291	32%	0.32	S	S	.	.	H	α-helix	trans	-59.9	-38.5	177.4	175.7	0	0	0	0	112	W259 V279 P280 W281 P287	W259-V283 HydrophobicContact CB-CG1 4.06Å; V279-V283 WeakPolarHBondContact O-CG2 3.47Å; V279-V283 PolarHBondContact O-N 3.47Å; P280-V283 PolarHBondContact O-N 3.48Å; W281-V283 VanDerWaalsContact C-N 3.3Å; W281-V283 PolarHBondContact O-N 3.33Å; V283-P287 WeakPolarHBondContact O-CD 3.39Å; V283-P287 WeakPolarHBondContact O-CG 3.24Å
284	I	86.8	Confident	82.3	Confident	17 Å²	17	61.3 Å²	61.3	9%	0.087	31%	0.314	C	S	.	.	H	α-helix	trans	-79.6	-42.3	173.3	-79.8	179.2	0	0	0	111.6	Q210 M214 I256 W259 W281 W282 I286 P287 I288	Q210-I284 HydrophobicContact CB-CD1 4.05Å; Q210-I284 HydrophobicContact CG-CD1 3.95Å; M214-I284 HydrophobicContact CE-CB 4.45Å; M214-I284 HydrophobicContact CE-CG1 4.24Å; M214-I284 HydrophobicContact CE-CG2 4.19Å; I256-I284 HydrophobicContact CD1-CD1 4.33Å; I256-I284 HydrophobicContact CD1-CG1 4.49Å; W259-I284 HydrophobicContact CB-CD1 4.17Å; W259-I284 HydrophobicContact CB-CG1 3.84Å; W259-I284 VanDerWaalsContact CD1-CD1 3.46Å; W259-I284 VanDerWaalsContact CD1-CG1 3.44Å; W259-I284 HydrophobicContact CD2-CD1 3.33Å; W259-I284 HydrophobicContact CD2-CG1 4Å; W259-I284 HydrophobicContact CE3-CD1 3.99Å; W259-I284 HydrophobicContact CG-CD1 3.39Å; W259-I284 HydrophobicContact CG-CG1 3.47Å; W259-I284 VanDerWaalsContact CG-CG1 3.47Å; W259-I284 HydrophobicContact CZ2-CD1 3.93Å; W281-I284 PolarHBondContact O-N 2.96Å; W282-I284 VanDerWaalsContact C-N 3.3Å; W282-I284 PolarHBondContact O-N 3.42Å; I284-I286 PolarHBondContact O-N 3.32Å; I284-P287 WeakPolarHBondContact O-CD 3.43Å; I284-I288 HydrophobicContact CG2-CD1 3.73Å; I284-I288 WeakPolarHBondContact O-CG1 3.05Å
285	R	85.4	Confident	83.4	Confident	92 Å²	92	58.8 Å²	58.8	35%	0.347	30%	0.298	S	S	.	.	H	α-helix	trans	-69.2	-35.8	-170.2	-165	172	-177.8	175.4	0.1	112.7	W281 W282 I288 L289	W281-R285 WeakPolarHBondContact O-CB 3.27Å; W281-R285 PolarHBondContact O-N 2.95Å; W282-R285 PolarHBondContact O-N 2.98Å; R285-I288 PolarHBondContact O-N 3Å; R285-L289 HydrophobicContact CG-CD1 3.84Å; R285-L289 HydrophobicContact CG-CG 4.22Å; R285-L289 WeakPolarHBondContact O-CB 3.32Å; R285-L289 WeakPolarHBondContact O-CG 3.28Å; R285-L289 PolarHBondContact O-N 3.14Å
286	I	88.5	Confident	84.4	Confident	82 Å²	82	59.3 Å²	59.3	42%	0.421	30%	0.298	S	S	.	.	H	α-helix	trans	-61.8	-54.3	-178.1	-71.1	167.2	0	0	0	112.2	W282 I284 I288 L289 I290	W282-I286 HydrophobicContact CB-CD1 4.24Å; W282-I286 HydrophobicContact CE3-CD1 4.33Å; W282-I286 HydrophobicContact CE3-CG1 3.95Å; W282-I286 WeakPolarHBondContact O-CB 3.46Å; W282-I286 VanDerWaalsContact O-CG1 3.24Å; W282-I286 WeakPolarHBondContact O-CG1 3.25Å; W282-I286 PolarHBondContact O-N 2.95Å; I284-I286 PolarHBondContact O-N 3.32Å; I286-I288 VanDerWaalsContact C-N 3.29Å; I286-I288 PolarHBondContact O-N 3.23Å; I286-L289 PolarHBondContact O-N 2.91Å; I286-I290 HydrophobicContact CG2-CD1 3.7Å; I286-I290 HydrophobicContact CG2-CG1 4.41Å; I286-I290 WeakPolarHBondContact O-CG1 3.46Å; I286-I290 PolarHBondContact O-N 3.46Å
287	P	92	Very high	85.7	Confident	25 Å²	25	58.4 Å²	58.4	16%	0.162	30%	0.296	C	S	.	.	H	α-helix	trans	-56.7	-40	177.3	-27.2	34.1	0	0	0	113.7	M214 F218 C255 V283 I284 I290 S291	M214-P287 HydrophobicContact SD-CB 4.12Å; F218-P287 HydrophobicContact CZ-CB 4.4Å; C255-P287 HydrophobicContact CB-CG 4.38Å; V283-P287 WeakPolarHBondContact O-CD 3.39Å; V283-P287 WeakPolarHBondContact O-CG 3.24Å; I284-P287 WeakPolarHBondContact O-CD 3.43Å; P287-I290 PolarHBondContact O-N 3.32Å; P287-S291 WeakPolarHBondContact O-CB 3Å; P287-S291 PolarHBondContact O-N 3.47Å
288	I	88.6	Confident	86.7	Confident	23 Å²	23	54.5 Å²	54.5	12%	0.118	28%	0.278	C	S	.	.	H	α-helix	trans	-63.8	-49.6	177.7	-65.1	174	0	0	0	110.2	M214 F217 I284 R285 I286 I290 S291 I292	M214-I288 HydrophobicContact CE-CD1 4.5Å; M214-I288 HydrophobicContact CE-CG1 4.35Å; M214-I288 HydrophobicContact SD-CD1 4.29Å; M214-I288 HydrophobicContact SD-CG1 3.66Å; F217-I288 HydrophobicContact CD1-CG2 4.41Å; F217-I288 HydrophobicContact CD2-CD1 4.46Å; F217-I288 HydrophobicContact CD2-CG1 4.32Å; F217-I288 HydrophobicContact CD2-CG2 3.82Å; F217-I288 HydrophobicContact CE1-CG2 4.38Å; F217-I288 HydrophobicContact CE2-CG2 3.79Å; F217-I288 HydrophobicContact CG-CG2 4.15Å; F217-I288 HydrophobicContact CZ-CG2 4.08Å; I284-I288 HydrophobicContact CG2-CD1 3.73Å; I284-I288 WeakPolarHBondContact O-CG1 3.05Å; R285-I288 PolarHBondContact O-N 3Å; I286-I288 VanDerWaalsContact C-N 3.29Å; I286-I288 PolarHBondContact O-N 3.23Å; I288-I290 PolarHBondContact O-N 3.45Å; I288-S291 WeakPolarHBondContact O-CB 3.46Å; I288-S291 PolarHBondContact O-N 2.9Å; I288-I292 HydrophobicContact CG2-CD1 3.65Å; I288-I292 HydrophobicContact CG2-CG1 4.32Å; I288-I292 VanDerWaalsContact O-CG1 3.23Å; I288-I292 WeakPolarHBondContact O-CG1 3.41Å; I288-I292 PolarHBondContact O-N 2.92Å
289	L	86.7	Confident	87.3	Confident	44 Å²	44	51.7 Å²	51.7	23%	0.23	26%	0.256	C	S	.	.	H	α-helix	trans	-58.2	-45.7	177.9	-76.9	167.6	0	0	0	111.9	R285 I286 S291 I292 I293 A345	R285-L289 HydrophobicContact CG-CD1 3.84Å; R285-L289 HydrophobicContact CG-CG 4.22Å; R285-L289 WeakPolarHBondContact O-CB 3.32Å; R285-L289 WeakPolarHBondContact O-CG 3.28Å; R285-L289 PolarHBondContact O-N 3.14Å; I286-L289 PolarHBondContact O-N 2.91Å; L289-S291 PolarHBondContact O-N 2.98Å; L289-I292 PolarHBondContact O-N 3.32Å; L289-I293 VanDerWaalsContact O-CG1 3.28Å; L289-I293 WeakPolarHBondContact O-CG1 3.34Å; L289-I293 PolarHBondContact O-N 3.31Å; L289-A345 HydrophobicContact CD2-CB 4.1Å
290	I	90.8	Very high	87.6	Confident	96 Å²	96	50.6 Å²	50.6	49%	0.492	25%	0.247	S	C	.	.	H	α-helix	trans	-59.3	-47.9	176.5	-67.8	168.9	0	0	0	110.3	I286 P287 I288 I292 I293 V294	I286-I290 HydrophobicContact CG2-CD1 3.7Å; I286-I290 HydrophobicContact CG2-CG1 4.41Å; I286-I290 WeakPolarHBondContact O-CG1 3.46Å; I286-I290 PolarHBondContact O-N 3.46Å; P287-I290 PolarHBondContact O-N 3.32Å; I288-I290 PolarHBondContact O-N 3.45Å; I290-I292 VanDerWaalsContact C-N 3.3Å; I290-I292 PolarHBondContact O-N 3.43Å; I290-I293 PolarHBondContact O-N 3.41Å; I290-V294 HydrophobicContact CG2-CG2 4.31Å; I290-V294 VanDerWaalsContact O-CG2 3.32Å; I290-V294 WeakPolarHBondContact O-CG2 3.35Å; I290-V294 PolarHBondContact O-N 3.49Å
291	S	90.9	Very high	88	Confident	2 Å²	2	52.3 Å²	52.3	1%	0.014	26%	0.259	C	S	.	.	H	α-helix	trans	-58.6	-42.2	178.9	-174.4	0	0	0	0	111.9	F217 P287 I288 L289 N295	F217-S291 PolarHBondContact O-OG 2.93Å; P287-S291 WeakPolarHBondContact O-CB 3Å; P287-S291 PolarHBondContact O-N 3.47Å; I288-S291 WeakPolarHBondContact O-CB 3.46Å; I288-S291 PolarHBondContact O-N 2.9Å; L289-S291 PolarHBondContact O-N 2.98Å; S291-N295 WeakPolarHBondContact O-CB 3.4Å; S291-N295 PolarHBondContact O-N 3.4Å; S291-N295 PolarHBondContact O-ND2 2.79Å
292	I	87.5	Confident	88.2	Confident	10 Å²	10	47.7 Å²	47.7	5%	0.051	24%	0.242	C	C	.	.	H	α-helix	trans	-69.3	-41.9	179.2	-59.1	162.7	0	0	0	110.7	F217 I288 L289 I290 N295 F296 Y341 M342	F217-I292 HydrophobicContact CD1-CD1 4.19Å; F217-I292 HydrophobicContact CD1-CG1 3.79Å; F217-I292 HydrophobicContact CE1-CD1 3.73Å; F217-I292 HydrophobicContact CE1-CG1 3.76Å; F217-I292 HydrophobicContact CZ-CD1 4.24Å; I288-I292 HydrophobicContact CG2-CD1 3.65Å; I288-I292 HydrophobicContact CG2-CG1 4.32Å; I288-I292 VanDerWaalsContact O-CG1 3.23Å; I288-I292 WeakPolarHBondContact O-CG1 3.41Å; I288-I292 PolarHBondContact O-N 2.92Å; L289-I292 PolarHBondContact O-N 3.32Å; I290-I292 VanDerWaalsContact C-N 3.3Å; I290-I292 PolarHBondContact O-N 3.43Å; I292-N295 WeakPolarHBondContact O-CB 3.45Å; I292-N295 PolarHBondContact O-N 3.44Å; I292-F296 PolarHBondContact O-N 2.93Å; I292-Y341 HydrophobicContact CD1-CG 4.45Å; I292-M342 HydrophobicContact CB-CE 3.51Å; I292-M342 HydrophobicContact CG2-CE 3.14Å; I292-M342 HydrophobicContact CG2-CG 3.6Å; I292-M342 HydrophobicContact CG2-SD 3.92Å
293	I	88.3	Confident	88.2	Confident	88 Å²	88	43.2 Å²	43.2	45%	0.451	23%	0.226	S	C	.	.	H	α-helix	trans	-61.2	-47.7	177	-69.2	165.8	0	0	0	110.6	L289 I290 N295 F296 V297 M342	L289-I293 VanDerWaalsContact O-CG1 3.28Å; L289-I293 WeakPolarHBondContact O-CG1 3.34Å; L289-I293 PolarHBondContact O-N 3.31Å; I290-I293 PolarHBondContact O-N 3.41Å; I293-N295 VanDerWaalsContact C-N 3.32Å; I293-N295 PolarHBondContact O-N 3.29Å; I293-F296 WeakPolarHBondContact O-CB 3.31Å; I293-F296 PolarHBondContact O-N 2.9Å; I293-V297 WeakPolarHBondContact O-CG2 3.08Å; I293-V297 PolarHBondContact O-N 2.92Å; I293-M342 HydrophobicContact CB-SD 4.4Å; I293-M342 HydrophobicContact CG1-CE 3.74Å; I293-M342 HydrophobicContact CG1-SD 3.73Å
294	V	91	Very high	88.2	Confident	57 Å²	57	48.9 Å²	48.9	35%	0.345	24%	0.243	S	C	.	.	H	α-helix	trans	-61.7	-43.3	178.1	176.5	0	0	0	0	110.3	L221 I290 F296 V297 L298	L221-V294 HydrophobicContact CD1-CB 4.04Å; L221-V294 HydrophobicContact CD1-CG1 3.61Å; I290-V294 HydrophobicContact CG2-CG2 4.31Å; I290-V294 VanDerWaalsContact O-CG2 3.32Å; I290-V294 WeakPolarHBondContact O-CG2 3.35Å; I290-V294 PolarHBondContact O-N 3.49Å; V294-F296 VanDerWaalsContact C-N 3.3Å; V294-F296 PolarHBondContact O-N 3.24Å; V294-V297 PolarHBondContact O-N 2.78Å; V294-L298 HydrophobicContact CG1-CD1 4.06Å; V294-L298 HydrophobicContact CG1-CG 4.34Å; V294-L298 VanDerWaalsContact O-CG 3.28Å; V294-L298 WeakPolarHBondContact O-CG 3.46Å; V294-L298 PolarHBondContact O-N 3.48Å
295	N	88.9	Confident	88	Confident	2 Å²	2	49.2 Å²	49.2	1%	0.011	24%	0.244	C	C	.	.	H	α-helix	trans	-58	-40.9	174.5	-94	-31	0	0	0	113.4	L220 L221 S291 I292 I293 L298 F299	L220-N295 PolarHBondContact O-OD1 3.44Å; L221-N295 WeakPolarHBondContact CA-ND2 3.44Å; L221-N295 WeakPolarHBondContact CA-OD1 3.11Å; L221-N295 PolarHBondContact N-ND2 3.13Å; S291-N295 WeakPolarHBondContact O-CB 3.4Å; S291-N295 PolarHBondContact O-N 3.4Å; S291-N295 PolarHBondContact O-ND2 2.79Å; I292-N295 WeakPolarHBondContact O-CB 3.45Å; I292-N295 PolarHBondContact O-N 3.44Å; I293-N295 VanDerWaalsContact C-N 3.32Å; I293-N295 PolarHBondContact O-N 3.29Å; N295-L298 PolarHBondContact O-N 2.06Å; N295-F299 WeakPolarHBondContact O-CB 3.48Å; N295-F299 PolarHBondContact O-N 3.25Å
296	F	87.3	Confident	87.8	Confident	76 Å²	76	47.2 Å²	47.2	33%	0.333	24%	0.24	S	C	.	.	H	α-helix	trans	-65.2	-43.2	176.8	-176.2	-105.3	0	0	0	112	I292 I293 V294 L298 F299 I300 V339 M342	I292-F296 PolarHBondContact O-N 2.93Å; I293-F296 WeakPolarHBondContact O-CB 3.31Å; I293-F296 PolarHBondContact O-N 2.9Å; V294-F296 VanDerWaalsContact C-N 3.3Å; V294-F296 PolarHBondContact O-N 3.24Å; F296-L298 VanDerWaalsContact C-N 3.33Å; F296-L298 PolarHBondContact O-N 2.98Å; F296-F299 WeakPolarHBondContact O-CB 3.3Å; F296-F299 PolarHBondContact O-N 2.93Å; F296-I300 HydrophobicContact CD1-CG1 4.49Å; F296-I300 HydrophobicContact CE1-CG1 4.12Å; F296-I300 HydrophobicContact CE2-CD1 4.38Å; F296-I300 HydrophobicContact CZ-CD1 4.1Å; F296-I300 HydrophobicContact CZ-CG1 4.15Å; F296-I300 WeakPolarHBondContact O-CG1 3.4Å; F296-I300 PolarHBondContact O-N 3.36Å; F296-V339 HydrophobicContact CD2-CB 4.45Å; F296-V339 HydrophobicContact CD2-CG1 3.79Å; F296-V339 HydrophobicContact CD2-CG2 4.15Å; F296-V339 HydrophobicContact CE2-CG1 3.73Å; F296-M342 HydrophobicContact CB-CG 3.78Å; F296-M342 HydrophobicContact CB-SD 4.36Å; F296-M342 HydrophobicContact CD2-CB 4.5Å; F296-M342 HydrophobicContact CD2-CG 4.19Å; F296-M342 HydrophobicContact CG-CG 4Å
297	V	89.3	Confident	87.5	Confident	92 Å²	92	46.4 Å²	46.4	56%	0.558	24%	0.236	S	C	*	.	H	α-helix	trans	-60.9	-43.6	174.7	174.3	0	0	0	0	111.1	I293 V294 I300 S301	I293-V297 WeakPolarHBondContact O-CG2 3.08Å; I293-V297 PolarHBondContact O-N 2.92Å; V294-V297 PolarHBondContact O-N 2.78Å; V297-I300 PolarHBondContact O-N 3.43Å; V297-S301 PolarHBondContact O-N 3.47Å
298	L	89.4	Confident	86.9	Confident	16 Å²	16	51.5 Å²	51.5	8%	0.084	26%	0.258	C	S	.	.	H	α-helix	trans	-61.8	-43.4	175.5	-67.8	171.6	0	0	0	111.5	L221 L225 H228 V294 N295 F296 I300 S301 I302	L221-L298 HydrophobicContact CD1-CD1 3.91Å; L225-L298 HydrophobicContact CD2-CD1 3.65Å; L225-L298 HydrophobicContact CD2-CD2 4.13Å; L225-L298 HydrophobicContact CG-CD1 3.81Å; H228-L298 HydrophobicContact CB-CD2 3.94Å; V294-L298 HydrophobicContact CG1-CD1 4.06Å; V294-L298 HydrophobicContact CG1-CG 4.34Å; V294-L298 VanDerWaalsContact O-CG 3.28Å; V294-L298 WeakPolarHBondContact O-CG 3.46Å; V294-L298 PolarHBondContact O-N 3.48Å; N295-L298 PolarHBondContact O-N 2.06Å; F296-L298 VanDerWaalsContact C-N 3.33Å; F296-L298 PolarHBondContact O-N 2.98Å; L298-I300 PolarHBondContact O-N 3.31Å; L298-S301 WeakPolarHBondContact O-CB 3.05Å; L298-S301 PolarHBondContact O-N 3.23Å; L298-I302 WeakPolarHBondContact O-CB 3.48Å; L298-I302 WeakPolarHBondContact O-CD1 3.3Å; L298-I302 WeakPolarHBondContact O-CG1 3.5Å; L298-I302 PolarHBondContact O-N 2.95Å
299	F	87.7	Confident	86.3	Confident	16 Å²	16	56.2 Å²	56.2	7%	0.07	28%	0.278	C	S	.	.	H	α-helix	trans	-57.3	-50	175.6	172	-111.4	0	0	0	111.4	N295 F296 S301 I302 I303 T330 L333 I334 F337 V339	N295-F299 WeakPolarHBondContact O-CB 3.48Å; N295-F299 PolarHBondContact O-N 3.25Å; F296-F299 WeakPolarHBondContact O-CB 3.3Å; F296-F299 PolarHBondContact O-N 2.93Å; F299-S301 VanDerWaalsContact C-N 3.32Å; F299-S301 PolarHBondContact O-N 2.82Å; F299-I302 PolarHBondContact O-N 3.27Å; F299-I303 HydrophobicContact CD2-CD1 4.44Å; F299-I303 HydrophobicContact CD2-CG1 3.96Å; F299-I303 HydrophobicContact CE1-CG1 4.3Å; F299-I303 HydrophobicContact CE2-CD1 3.85Å; F299-I303 HydrophobicContact CE2-CG1 3.65Å; F299-I303 HydrophobicContact CG-CG1 4.46Å; F299-I303 HydrophobicContact CZ-CD1 4.25Å; F299-I303 HydrophobicContact CZ-CG1 3.83Å; F299-I303 VanDerWaalsContact O-CG1 3.28Å; F299-I303 WeakPolarHBondContact O-CG1 3.3Å; F299-I303 PolarHBondContact O-N 3.36Å; F299-T330 HydrophobicContact CE2-CG2 4.32Å; F299-T330 HydrophobicContact CZ-CG2 4Å; F299-L333 HydrophobicContact CD2-CD2 4.09Å; F299-L333 HydrophobicContact CD2-CG 4.37Å; F299-L333 HydrophobicContact CE2-CB 4.22Å; F299-L333 HydrophobicContact CE2-CD2 4Å; F299-L333 HydrophobicContact CE2-CG 4.23Å; F299-I334 HydrophobicContact CE1-CG1 4.45Å; F299-I334 HydrophobicContact CE2-CG1 4.34Å; F299-I334 HydrophobicContact CZ-CG1 3.72Å; F299-F337 HydrophobicContact CB-CB 4.46Å; F299-F337 HydrophobicContact CB-CD2 3.92Å; F299-F337 HydrophobicContact CB-CE2 4.44Å; F299-F337 HydrophobicContact CB-CG 4.35Å; F299-F337 AromaticContact CD2-CD2 3.4Å; F299-F337 HydrophobicContact CD2-CD2 3.4Å; F299-F337 AromaticContact CD2-CE2 3.84Å; F299-F337 HydrophobicContact CD2-CE2 3.84Å; F299-F337 HydrophobicContact CD2-CG 4.45Å; F299-F337 HydrophobicContact CE2-CD2 4.25Å; F299-F337 HydrophobicContact CG-CD2 4.02Å; F299-V339 HydrophobicContact CB-CG2 4.48Å; F299-V339 HydrophobicContact CD1-CG2 3.84Å; F299-V339 HydrophobicContact CE1-CG2 4.19Å; F299-V339 HydrophobicContact CG-CG2 4.09Å
300	I	86.4	Confident	85.3	Confident	60 Å²	60	57.3 Å²	57.3	31%	0.308	28%	0.284	S	S	.	.	H	α-helix	trans	-60.3	-42.2	177.4	-61.9	-58.7	0	0	0	111.3	F296 V297 L298 I303 R304	F296-I300 HydrophobicContact CD1-CG1 4.49Å; F296-I300 HydrophobicContact CE1-CG1 4.12Å; F296-I300 HydrophobicContact CE2-CD1 4.38Å; F296-I300 HydrophobicContact CZ-CD1 4.1Å; F296-I300 HydrophobicContact CZ-CG1 4.15Å; F296-I300 WeakPolarHBondContact O-CG1 3.4Å; F296-I300 PolarHBondContact O-N 3.36Å; V297-I300 PolarHBondContact O-N 3.43Å; L298-I300 PolarHBondContact O-N 3.31Å; I300-I303 PolarHBondContact O-N 2.64Å; I300-R304 VanDerWaalsContact O-CG 3.31Å; I300-R304 WeakPolarHBondContact O-CG 3.21Å; I300-R304 PolarHBondContact O-N 3.3Å
301	S	88.6	Confident	84.3	Confident	35 Å²	35	57.1 Å²	57.1	25%	0.245	29%	0.287	C	S	.	.	H	α-helix	trans	-61	-48.2	176.2	-174.3	0	0	0	0	112	H228 V297 L298 F299 I303 R304 I305	H228-S301 PolarHBondContact CD2-OG 2.95Å; H228-S301 VanDerWaalsContact CD2-OG 3.31Å; H228-S301 PolarHBondContact NE2-OG 3.25Å; V297-S301 PolarHBondContact O-N 3.47Å; L298-S301 WeakPolarHBondContact O-CB 3.05Å; L298-S301 PolarHBondContact O-N 3.23Å; F299-S301 VanDerWaalsContact C-N 3.32Å; F299-S301 PolarHBondContact O-N 2.82Å; S301-I303 PolarHBondContact O-N 3.1Å; S301-R304 WeakPolarHBondContact O-CB 3.03Å; S301-R304 PolarHBondContact O-N 3.38Å; S301-I305 VanDerWaalsContact O-CG1 3.31Å; S301-I305 WeakPolarHBondContact O-CG1 3.07Å; S301-I305 PolarHBondContact O-N 2.87Å
302	I	86	Confident	83	Confident	0 Å²	0	60.7 Å²	60.7	0%	0	31%	0.312	C	S	.	.	H	α-helix	trans	-60.8	-44.9	178.6	-69.5	163	0	0	0	110.5	L227 H228 L231 L298 F299 R304 I305 L306 L333 F337	L227-I302 HydrophobicContact CB-CD1 4.21Å; L227-I302 HydrophobicContact CD2-CD1 4.04Å; L227-I302 HydrophobicContact CD2-CG2 4.14Å; L227-I302 HydrophobicContact CG-CD1 4.11Å; H228-I302 HydrophobicContact CB-CD1 4.31Å; H228-I302 HydrophobicContact CB-CG1 4.27Å; L231-I302 HydrophobicContact CD1-CB 4.41Å; L231-I302 HydrophobicContact CD1-CG1 4.18Å; L231-I302 HydrophobicContact CD1-CG2 3.91Å; L298-I302 WeakPolarHBondContact O-CB 3.48Å; L298-I302 WeakPolarHBondContact O-CD1 3.3Å; L298-I302 WeakPolarHBondContact O-CG1 3.5Å; L298-I302 PolarHBondContact O-N 2.95Å; F299-I302 PolarHBondContact O-N 3.27Å; I302-R304 PolarHBondContact O-N 3Å; I302-I305 PolarHBondContact O-N 2.96Å; I302-L306 HydrophobicContact CG2-CD1 3.72Å; I302-L306 HydrophobicContact CG2-CG 4.25Å; I302-L306 WeakPolarHBondContact O-CB 3.35Å; I302-L306 VanDerWaalsContact O-CG 3.25Å; I302-L306 WeakPolarHBondContact O-CG 3.4Å; I302-L306 PolarHBondContact O-N 3.14Å; I302-L333 HydrophobicContact CG2-CD2 4.47Å; I302-F337 HydrophobicContact CD1-CE2 4.35Å; I302-F337 HydrophobicContact CD1-CZ 3.98Å
303	I	83.8	Confident	81.3	Confident	26 Å²	26	66 Å²	66	13%	0.133	35%	0.347	C	S	.	.	H	α-helix	trans	-62.3	-42.4	177.2	-66.8	-57.6	0	0	0	111.4	F299 I300 S301 L306 L307 T330 L333	F299-I303 HydrophobicContact CD2-CD1 4.44Å; F299-I303 HydrophobicContact CD2-CG1 3.96Å; F299-I303 HydrophobicContact CE1-CG1 4.3Å; F299-I303 HydrophobicContact CE2-CD1 3.85Å; F299-I303 HydrophobicContact CE2-CG1 3.65Å; F299-I303 HydrophobicContact CG-CG1 4.46Å; F299-I303 HydrophobicContact CZ-CD1 4.25Å; F299-I303 HydrophobicContact CZ-CG1 3.83Å; F299-I303 VanDerWaalsContact O-CG1 3.28Å; F299-I303 WeakPolarHBondContact O-CG1 3.3Å; F299-I303 PolarHBondContact O-N 3.36Å; I300-I303 PolarHBondContact O-N 2.64Å; S301-I303 PolarHBondContact O-N 3.1Å; I303-L306 HydrophobicContact CD1-CD1 4.5Å; I303-L306 PolarHBondContact O-N 3.45Å; I303-L307 HydrophobicContact CG2-CD1 3.78Å; I303-L307 HydrophobicContact CG2-CG 4.36Å; I303-L307 WeakPolarHBondContact O-CB 3.3Å; I303-L307 VanDerWaalsContact O-CG 3.28Å; I303-L307 WeakPolarHBondContact O-CG 3.42Å; I303-L307 PolarHBondContact O-N 3.43Å; I303-T330 HydrophobicContact CD1-CG2 3.48Å; I303-T330 VanDerWaalsContact CD1-CG2 3.48Å; I303-T330 WeakPolarHBondContact CD1-OG1 3.45Å; I303-T330 HydrophobicContact CG1-CG2 4.25Å; I303-L333 HydrophobicContact CD1-CD2 4.27Å
304	R	87.3	Confident	79.8	Confident	168 Å²	168	69.6 Å²	69.6	63%	0.634	37%	0.367	S	S	*	.	H	α-helix	trans	-60.2	-46.8	175.1	-74.6	176.9	179.7	-169.1	0.7	111.8	I300 S301 I302 L307 Q308	I300-R304 VanDerWaalsContact O-CG 3.31Å; I300-R304 WeakPolarHBondContact O-CG 3.21Å; I300-R304 PolarHBondContact O-N 3.3Å; S301-R304 WeakPolarHBondContact O-CB 3.03Å; S301-R304 PolarHBondContact O-N 3.38Å; I302-R304 PolarHBondContact O-N 3Å; R304-L307 PolarHBondContact O-N 3.2Å; R304-Q308 VanDerWaalsContact O-CG 3.3Å; R304-Q308 WeakPolarHBondContact O-CG 3.27Å; R304-Q308 PolarHBondContact O-N 2.94Å
305	I	83.9	Confident	78.1	Confident	24 Å²	24	71.7 Å²	71.7	12%	0.123	38%	0.38	C	S	.	.	H	α-helix	trans	-64.5	-42.3	179.1	-64.7	162.5	0	0	0	110.9	L231 V232 S301 I302 Q308 K309	L231-I305 HydrophobicContact CB-CD1 4.44Å; L231-I305 HydrophobicContact CB-CG2 4.27Å; L231-I305 HydrophobicContact CD2-CG2 4.4Å; V232-I305 HydrophobicContact CG2-CD1 3.5Å; V232-I305 VanDerWaalsContact CG2-CD1 3.5Å; S301-I305 VanDerWaalsContact O-CG1 3.31Å; S301-I305 WeakPolarHBondContact O-CG1 3.07Å; S301-I305 PolarHBondContact O-N 2.87Å; I302-I305 PolarHBondContact O-N 2.96Å; I305-Q308 PolarHBondContact O-N 2.98Å; I305-K309 HydrophobicContact CG2-CD 4.32Å; I305-K309 WeakPolarHBondContact O-CG 3.29Å; I305-K309 PolarHBondContact O-N 3.49Å
306	L	81.5	Confident	76.3	Confident	50 Å²	50	75.9 Å²	75.9	26%	0.262	42%	0.424	S	S	.	.	H	α-helix	trans	-63.8	-43.1	177.1	-74.1	172	0	0	0	111.6	I302 I303 K309 L310	I302-L306 HydrophobicContact CG2-CD1 3.72Å; I302-L306 HydrophobicContact CG2-CG 4.25Å; I302-L306 WeakPolarHBondContact O-CB 3.35Å; I302-L306 VanDerWaalsContact O-CG 3.25Å; I302-L306 WeakPolarHBondContact O-CG 3.4Å; I302-L306 PolarHBondContact O-N 3.14Å; I303-L306 HydrophobicContact CD1-CD1 4.5Å; I303-L306 PolarHBondContact O-N 3.45Å; L306-K309 PolarHBondContact O-N 2.88Å; L306-L310 WeakPolarHBondContact O-CB 3.42Å; L306-L310 WeakPolarHBondContact O-CD1 3.35Å; L306-L310 VanDerWaalsContact O-CG 3.24Å; L306-L310 WeakPolarHBondContact O-CG 3.39Å; L306-L310 PolarHBondContact O-N 2.97Å
307	L	80.6	Confident	74.8	Confident	65 Å²	65	74.5 Å²	74.5	34%	0.34	43%	0.43	S	S	.	.	H	α-helix	trans	-61.7	-44.6	174.9	-77	166.1	0	0	0	111.5	I303 R304 L310 T311 L326	I303-L307 HydrophobicContact CG2-CD1 3.78Å; I303-L307 HydrophobicContact CG2-CG 4.36Å; I303-L307 WeakPolarHBondContact O-CB 3.3Å; I303-L307 VanDerWaalsContact O-CG 3.28Å; I303-L307 WeakPolarHBondContact O-CG 3.42Å; I303-L307 PolarHBondContact O-N 3.43Å; R304-L307 PolarHBondContact O-N 3.2Å; L307-L310 PolarHBondContact O-N 2.81Å; L307-T311 WeakPolarHBondContact O-CB 3.11Å; L307-T311 PolarHBondContact O-N 2.98Å; L307-T311 PolarHBondContact O-OG1 2.8Å; L307-L326 HydrophobicContact CD2-CD2 3.29Å; L307-L326 HydrophobicContact CG-CD2 4.06Å
308	Q	81.2	Confident	73.4	Confident	132 Å²	132	75 Å²	75	62%	0.617	43%	0.43	S	S	*	.	H	α-helix	trans	-62.8	-44	177.7	-74.1	172.3	-17.1	0	0	112.5	R304 I305 L310 T311 S312	R304-Q308 VanDerWaalsContact O-CG 3.3Å; R304-Q308 WeakPolarHBondContact O-CG 3.27Å; R304-Q308 PolarHBondContact O-N 2.94Å; I305-Q308 PolarHBondContact O-N 2.98Å; Q308-L310 VanDerWaalsContact C-N 3.29Å; Q308-L310 PolarHBondContact O-N 3.1Å; Q308-T311 PolarHBondContact O-N 3.32Å; Q308-S312 PolarHBondContact O-N 3.48Å; Q308-S312 PolarHBondContact O-OG 2.81Å
309	K	74.5	Confident	72.1	Confident	121 Å²	121	79.2 Å²	79.2	53%	0.526	45%	0.453	S	S	.	.	H	α-helix	trans	-66.5	-30.3	177.5	-74.3	-173.3	178.5	-177.1	0	112.8	I305 L306	I305-K309 HydrophobicContact CG2-CD 4.32Å; I305-K309 WeakPolarHBondContact O-CG 3.29Å; I305-K309 PolarHBondContact O-N 3.49Å; L306-K309 PolarHBondContact O-N 2.88Å
310	L	66.8	Low	70.8	Confident	68 Å²	68	84.6 Å²	84.6	36%	0.356	48%	0.478	S	S	.	.	H	α-helix	trans	-82	-32.2	177.5	-72.1	168	0	0	0	113.2	L306 L307 Q308 S312 L326	L306-L310 WeakPolarHBondContact O-CB 3.42Å; L306-L310 WeakPolarHBondContact O-CD1 3.35Å; L306-L310 VanDerWaalsContact O-CG 3.24Å; L306-L310 WeakPolarHBondContact O-CG 3.39Å; L306-L310 PolarHBondContact O-N 2.97Å; L307-L310 PolarHBondContact O-N 2.81Å; Q308-L310 VanDerWaalsContact C-N 3.29Å; Q308-L310 PolarHBondContact O-N 3.1Å; L310-S312 PolarHBondContact O-N 3.45Å; L310-L326 HydrophobicContact CD1-CB 4.17Å; L310-L326 HydrophobicContact CD1-CD1 3.58Å; L310-L326 HydrophobicContact CD1-CD2 3.75Å; L310-L326 HydrophobicContact CD1-CG 4.03Å
311	T	69.2	Low	69.8	Low	91 Å²	91	84.2 Å²	84.2	56%	0.558	48%	0.481	S	S	*	.	H	α-helix	trans	-78.2	-7.6	175.5	-55.9	0	0	0	0	112.6	L307 Q308 P313	L307-T311 WeakPolarHBondContact O-CB 3.11Å; L307-T311 PolarHBondContact O-N 2.98Å; L307-T311 PolarHBondContact O-OG1 2.8Å; Q308-T311 PolarHBondContact O-N 3.32Å; T311-P313 WeakPolarHBondContact O-CD 3.29Å
312	S	63.5	Low	68.6	Low	78 Å²	78	84.8 Å²	84.8	55%	0.545	48%	0.479	S	S	.	.	S	Bend	trans	-66	118.5	174.8	-62.8	0	0	0	0	109.7	Q308 L310 D314	Q308-S312 PolarHBondContact O-N 3.48Å; Q308-S312 PolarHBondContact O-OG 2.81Å; L310-S312 PolarHBondContact O-N 3.45Å; S312-D314 PolarHBondContact O-N 3.08Å; S312-D314 VanDerWaalsContact O-N 3.17Å
313	P	52.8	Low	67.5	Low	121 Å²	121	91 Å²	91	79%	0.786	50%	0.504	S	S	*	.	S	Bend	trans	-87	93.5	-158.4	32.9	-34.9	0	0	0	112	T311	T311-P313 WeakPolarHBondContact O-CD 3.29Å
314	D	56.1	Low	66.6	Low	164 Å²	164	96.2 Å²	96.2	88%	0.877	53%	0.525	S	S	*	.	S	Bend	trans	-128.9	9.7	165.5	-104	-26.6	0	0	0	113.7	S312	S312-D314 PolarHBondContact O-N 3.08Å; S312-D314 VanDerWaalsContact O-N 3.17Å
315	V	55.8	Low	65.7	Low	100 Å²	100	96 Å²	96	61%	0.606	53%	0.525	S	S	*	.			trans	-138.8	91.7	174.6	-178.1	0	0	0	0	110.3	G317	V315-G317 PolarHBondContact O-N 3.43Å
316	G	50.9	Low	64.6	Low	91 Å²	91	95.9 Å²	95.9	94%	0.938	52%	0.524	S	S	*	.			trans	-64.9	107.1	159.9	0	0	0	0	0	109.4
317	G	55.6	Low	63.8	Low	46 Å²	46	96.3 Å²	96.3	47%	0.474	54%	0.535	S	S	.	.	S	Bend	trans	144.9	110.3	171.4	0	0	0	0	0	114.9	V315	V315-G317 PolarHBondContact O-N 3.43Å
318	N	59.8	Low	63.4	Low	103 Å²	103	100.2 Å²	100.2	55%	0.551	55%	0.549	S	S	*	.			trans	79.2	54.1	167	-156.3	7.9	0	0	0	117.9	Q320 S321 Q322	N318-Q320 PolarHBondContact O-N 2.77Å; N318-Q320 VanDerWaalsContact O-N 3.13Å; N318-S321 WeakPolarHBondContact ND2-CB 3.5Å; N318-S321 PolarHBondContact ND2-OG 3.49Å; N318-S321 VanDerWaalsContact ND2-OG 3.1Å; N318-S321 PolarHBondContact O-N 3.27Å; N318-S321 PolarHBondContact O-OG 3.1Å; N318-S321 PolarHBondContact OD1-N 3.38Å; N318-Q322 PolarHBondContact O-N 3.37Å
319	D	61.5	Low	62.7	Low	105 Å²	105	97.3 Å²	97.3	56%	0.561	54%	0.543	S	S	*	.	H	α-helix	trans	-42.8	-44.8	171.5	-64.9	-13.5	0	0	0	112.8	S321 Q322 Y323	D319-S321 VanDerWaalsContact C-N 3.35Å; D319-S321 PolarHBondContact O-N 3.09Å; D319-Q322 PolarHBondContact O-N 3.3Å; D319-Y323 HydrophobicContact CB-CD2 4.15Å; D319-Y323 HydrophobicContact CB-CE2 3.97Å; D319-Y323 WeakPolarHBondContact O-CD2 3.49Å; D319-Y323 PolarHBondContact O-N 3.34Å
320	Q	61.3	Low	62.4	Low	129 Å²	129	92.8 Å²	92.8	60%	0.603	53%	0.526	S	S	*	.	H	α-helix	trans	-63.5	-36.8	-176.6	-156.3	-172.4	19.5	0	0	113.1	N318 K324	N318-Q320 PolarHBondContact O-N 2.77Å; N318-Q320 VanDerWaalsContact O-N 3.13Å; Q320-K324 WeakPolarHBondContact O-CB 3.46Å; Q320-K324 VanDerWaalsContact O-CG 3.26Å; Q320-K324 WeakPolarHBondContact O-CG 3.43Å; Q320-K324 PolarHBondContact O-N 2.96Å
321	S	65	Low	62.4	Low	51 Å²	51	95.1 Å²	95.1	36%	0.357	54%	0.538	S	S	.	.	H	α-helix	trans	-71	-35.4	176.9	71.8	0	0	0	0	112.6	N318 D319 R325	N318-S321 WeakPolarHBondContact ND2-CB 3.5Å; N318-S321 PolarHBondContact ND2-OG 3.49Å; N318-S321 VanDerWaalsContact ND2-OG 3.1Å; N318-S321 PolarHBondContact O-N 3.27Å; N318-S321 PolarHBondContact O-OG 3.1Å; N318-S321 PolarHBondContact OD1-N 3.38Å; D319-S321 VanDerWaalsContact C-N 3.35Å; D319-S321 PolarHBondContact O-N 3.09Å; S321-R325 WeakPolarHBondContact O-CB 3.37Å; S321-R325 PolarHBondContact O-N 3.03Å
322	Q	63.6	Low	62.4	Low	47 Å²	47	93.6 Å²	93.6	22%	0.22	53%	0.526	C	S	.	.	H	α-helix	trans	-70.9	-44.3	178.6	-61.3	-169.7	11.2	0	0	110.7	N318 D319 R325 L326	N318-Q322 PolarHBondContact O-N 3.37Å; D319-Q322 PolarHBondContact O-N 3.3Å; Q322-R325 PolarHBondContact O-N 2.84Å; Q322-L326 WeakPolarHBondContact O-CB 3.24Å; Q322-L326 PolarHBondContact O-N 3.17Å
323	Y	62.1	Low	62.8	Low	131 Å²	131	90.9 Å²	90.9	51%	0.514	51%	0.505	S	S	.	.	H	α-helix	trans	-61.7	-42.3	173	-74.3	-64.1	0	0	0	112.2	D319 R325 L326 A327	D319-Y323 HydrophobicContact CB-CD2 4.15Å; D319-Y323 HydrophobicContact CB-CE2 3.97Å; D319-Y323 WeakPolarHBondContact O-CD2 3.49Å; D319-Y323 PolarHBondContact O-N 3.34Å; Y323-R325 PolarHBondContact O-N 2.92Å; Y323-L326 PolarHBondContact O-N 2.84Å; Y323-A327 VanDerWaalsContact O-CB 3.32Å; Y323-A327 WeakPolarHBondContact O-CB 3.4Å; Y323-A327 PolarHBondContact O-N 2.92Å
324	K	65	Low	63.6	Low	135 Å²	135	88 Å²	88	59%	0.587	48%	0.483	S	S	*	.	H	α-helix	trans	-61.8	-42.3	175.1	-79.5	176.3	179.5	176.5	0	112.2	Q320 L326 K328	Q320-K324 WeakPolarHBondContact O-CB 3.46Å; Q320-K324 VanDerWaalsContact O-CG 3.26Å; Q320-K324 WeakPolarHBondContact O-CG 3.43Å; Q320-K324 PolarHBondContact O-N 2.96Å; K324-L326 VanDerWaalsContact C-N 3.35Å; K324-K328 WeakPolarHBondContact O-CB 3.39Å; K324-K328 PolarHBondContact O-N 3.11Å
325	R	68.7	Low	63.9	Low	165 Å²	165	82 Å²	82	62%	0.623	45%	0.453	S	S	*	.	H	α-helix	trans	-63.8	-41.4	176.2	-172.5	178.3	68.3	-166.5	0.1	111.4	S321 Q322 Y323 K328 S329	S321-R325 WeakPolarHBondContact O-CB 3.37Å; S321-R325 PolarHBondContact O-N 3.03Å; Q322-R325 PolarHBondContact O-N 2.84Å; Y323-R325 PolarHBondContact O-N 2.92Å; R325-K328 PolarHBondContact O-N 3.16Å; R325-S329 PolarHBondContact O-N 2.83Å
326	L	61.1	Low	64.4	Low	21 Å²	21	77.4 Å²	77.4	11%	0.11	43%	0.425	C	S	.	.	H	α-helix	trans	-66.3	-48.8	176.3	179.2	60.6	0	0	0	111.6	L307 L310 Q322 Y323 K324 K328 S329 T330	L307-L326 HydrophobicContact CD2-CD2 3.29Å; L307-L326 HydrophobicContact CG-CD2 4.06Å; L310-L326 HydrophobicContact CD1-CB 4.17Å; L310-L326 HydrophobicContact CD1-CD1 3.58Å; L310-L326 HydrophobicContact CD1-CD2 3.75Å; L310-L326 HydrophobicContact CD1-CG 4.03Å; Q322-L326 WeakPolarHBondContact O-CB 3.24Å; Q322-L326 PolarHBondContact O-N 3.17Å; Y323-L326 PolarHBondContact O-N 2.84Å; K324-L326 VanDerWaalsContact C-N 3.35Å; L326-K328 PolarHBondContact O-N 3.41Å; L326-S329 CarbonylContact O-C 3.58Å; L326-S329 WeakPolarHBondContact O-CA 3.38Å; L326-S329 WeakPolarHBondContact O-CB 3.4Å; L326-S329 PolarHBondContact O-N 3.41Å; L326-T330 WeakPolarHBondContact O-CB 3.4Å; L326-T330 PolarHBondContact O-N 2.87Å; L326-T330 PolarHBondContact O-OG1 3.36Å; L326-T330 VanDerWaalsContact O-OG1 3.06Å
327	A	64.1	Low	65.3	Low	59 Å²	59	73.2 Å²	73.2	49%	0.488	38%	0.381	S	S	.	.	H	α-helix	trans	-56.2	-40.7	176.9	0	0	0	0	0	111	Y323 T330 L331	Y323-A327 VanDerWaalsContact O-CB 3.32Å; Y323-A327 WeakPolarHBondContact O-CB 3.4Å; Y323-A327 PolarHBondContact O-N 2.92Å; A327-T330 PolarHBondContact O-N 3.31Å; A327-L331 WeakPolarHBondContact O-CB 3.32Å; A327-L331 PolarHBondContact O-N 3.07Å
328	K	72.2	Confident	65.8	Low	147 Å²	147	71.1 Å²	71.1	64%	0.639	36%	0.359	S	S	*	.	H	α-helix	trans	-61.4	-49.2	172.8	-172.1	176.7	-179	177.3	0	111.5	K324 R325 L326 T330 L331 L332	K324-K328 WeakPolarHBondContact O-CB 3.39Å; K324-K328 PolarHBondContact O-N 3.11Å; R325-K328 PolarHBondContact O-N 3.16Å; L326-K328 PolarHBondContact O-N 3.41Å; K328-T330 VanDerWaalsContact C-N 3.34Å; K328-T330 PolarHBondContact O-N 3.35Å; K328-L331 PolarHBondContact O-N 3.18Å; K328-L332 HydrophobicContact CG-CD1 4.02Å; K328-L332 WeakPolarHBondContact O-CB 3.49Å; K328-L332 VanDerWaalsContact O-CD1 3.31Å; K328-L332 WeakPolarHBondContact O-CD1 3.3Å; K328-L332 WeakPolarHBondContact O-CG 3.45Å; K328-L332 PolarHBondContact O-N 2.89Å; K328-L332 VanDerWaalsContact O-N 3.11Å
329	S	67.5	Low	66.4	Low	70 Å²	70	66.9 Å²	66.9	49%	0.49	34%	0.337	S	S	.	.	H	α-helix	trans	-61.3	-41	178.1	-165.5	0	0	0	0	112.5	R325 L326 L333	R325-S329 PolarHBondContact O-N 2.83Å; L326-S329 CarbonylContact O-C 3.58Å; L326-S329 WeakPolarHBondContact O-CA 3.38Å; L326-S329 WeakPolarHBondContact O-CB 3.4Å; L326-S329 PolarHBondContact O-N 3.41Å; S329-L333 WeakPolarHBondContact O-CB 3.48Å; S329-L333 PolarHBondContact O-N 3.24Å
330	T	67.4	Low	67.1	Low	26 Å²	26	62.7 Å²	62.7	16%	0.16	31%	0.314	C	S	.	.	H	α-helix	trans	-70.3	-43.1	179.1	-59.9	0	0	0	0	111.7	F299 I303 L326 A327 K328 L332 L333 I334	F299-T330 HydrophobicContact CE2-CG2 4.32Å; F299-T330 HydrophobicContact CZ-CG2 4Å; I303-T330 HydrophobicContact CD1-CG2 3.48Å; I303-T330 VanDerWaalsContact CD1-CG2 3.48Å; I303-T330 WeakPolarHBondContact CD1-OG1 3.45Å; I303-T330 HydrophobicContact CG1-CG2 4.25Å; L326-T330 WeakPolarHBondContact O-CB 3.4Å; L326-T330 PolarHBondContact O-N 2.87Å; L326-T330 PolarHBondContact O-OG1 3.36Å; L326-T330 VanDerWaalsContact O-OG1 3.06Å; A327-T330 PolarHBondContact O-N 3.31Å; K328-T330 VanDerWaalsContact C-N 3.34Å; K328-T330 PolarHBondContact O-N 3.35Å; T330-L332 PolarHBondContact O-N 3.38Å; T330-L333 WeakPolarHBondContact O-CA 3.43Å; T330-L333 VanDerWaalsContact O-CB 3.25Å; T330-L333 WeakPolarHBondContact O-CB 3.43Å; T330-L333 PolarHBondContact O-N 3.41Å; T330-I334 WeakPolarHBondContact O-CG1 3.37Å; T330-I334 PolarHBondContact O-N 3.35Å; T330-I334 VanDerWaalsContact O-N 3.12Å
331	L	67.1	Low	67.6	Low	118 Å²	118	57 Å²	57	62%	0.618	29%	0.287	S	S	*	.	H	α-helix	trans	-60.8	-37.1	177.1	-174.7	68.7	0	0	0	111.2	A327 K328 L333 I334 P335	A327-L331 WeakPolarHBondContact O-CB 3.32Å; A327-L331 PolarHBondContact O-N 3.07Å; K328-L331 PolarHBondContact O-N 3.18Å; L331-L333 PolarHBondContact O-N 2.92Å; L331-I334 HydrophobicContact CD1-CD1 4.29Å; L331-I334 PolarHBondContact O-N 2.59Å; L331-P335 WeakPolarHBondContact O-CD 3.24Å
332	L	69.1	Low	67.9	Low	58 Å²	58	55.2 Å²	55.2	30%	0.304	27%	0.273	S	S	.	.	H	α-helix	trans	-69.3	-24.2	175.1	-69	169.3	0	0	0	112.5	K328 T330 L374	K328-L332 HydrophobicContact CG-CD1 4.02Å; K328-L332 WeakPolarHBondContact O-CB 3.49Å; K328-L332 VanDerWaalsContact O-CD1 3.31Å; K328-L332 WeakPolarHBondContact O-CD1 3.3Å; K328-L332 WeakPolarHBondContact O-CG 3.45Å; K328-L332 PolarHBondContact O-N 2.89Å; K328-L332 VanDerWaalsContact O-N 3.11Å; T330-L332 PolarHBondContact O-N 3.38Å; L332-L374 HydrophobicContact CB-CD1 3.75Å; L332-L374 HydrophobicContact CB-CD2 3.78Å; L332-L374 HydrophobicContact CB-CG 4.42Å; L332-L374 HydrophobicContact CD1-CD2 3.56Å; L332-L374 HydrophobicContact CD2-CD1 4.35Å; L332-L374 HydrophobicContact CD2-CD2 3.8Å; L332-L374 HydrophobicContact CG-CD2 3.86Å; L332-L374 VanDerWaalsContact O-CD1 3.31Å; L332-L374 WeakPolarHBondContact O-CD1 3.2Å
333	L	71.4	Confident	68.3	Low	21 Å²	21	56.5 Å²	56.5	11%	0.11	29%	0.285	C	S	.	.	H	α-helix	trans	-85.1	-20.1	-179.9	-156.1	68.2	0	0	0	113	F299 I302 I303 S329 T330 L331 L336 F337	F299-L333 HydrophobicContact CD2-CD2 4.09Å; F299-L333 HydrophobicContact CD2-CG 4.37Å; F299-L333 HydrophobicContact CE2-CB 4.22Å; F299-L333 HydrophobicContact CE2-CD2 4Å; F299-L333 HydrophobicContact CE2-CG 4.23Å; I302-L333 HydrophobicContact CG2-CD2 4.47Å; I303-L333 HydrophobicContact CD1-CD2 4.27Å; S329-L333 WeakPolarHBondContact O-CB 3.48Å; S329-L333 PolarHBondContact O-N 3.24Å; T330-L333 WeakPolarHBondContact O-CA 3.43Å; T330-L333 VanDerWaalsContact O-CB 3.25Å; T330-L333 WeakPolarHBondContact O-CB 3.43Å; T330-L333 PolarHBondContact O-N 3.41Å; L331-L333 PolarHBondContact O-N 2.92Å; L333-L336 HydrophobicContact CD1-CD2 3.68Å; L333-L336 WeakPolarHBondContact O-CB 3.46Å; L333-L336 PolarHBondContact O-N 3.43Å; L333-F337 HydrophobicContact CD1-CD2 4.23Å; L333-F337 HydrophobicContact CD1-CE2 3.6Å; L333-F337 HydrophobicContact CD1-CZ 4.06Å; L333-F337 HydrophobicContact CD2-CD2 4.15Å; L333-F337 HydrophobicContact CD2-CE2 3.49Å; L333-F337 VanDerWaalsContact CD2-CE2 3.49Å; L333-F337 HydrophobicContact CD2-CZ 4.44Å; L333-F337 HydrophobicContact CG-CD2 3.61Å; L333-F337 HydrophobicContact CG-CE2 3.25Å; L333-F337 HydrophobicContact CG-CZ 4.2Å; L333-F337 WeakPolarHBondContact O-CD2 3.32Å; L333-F337 PolarHBondContact O-N 3.22Å; L333-F337 VanDerWaalsContact O-N 3.08Å
334	I	70.4	Confident	68.6	Low	60 Å²	60	52.5 Å²	52.5	31%	0.308	27%	0.27	S	S	.	.	H	α-helix	trans	-66	-51	-180	-71.5	168.9	0	0	0	112.6	F299 T330 L331 L336 V339	F299-I334 HydrophobicContact CE1-CG1 4.45Å; F299-I334 HydrophobicContact CE2-CG1 4.34Å; F299-I334 HydrophobicContact CZ-CG1 3.72Å; T330-I334 WeakPolarHBondContact O-CG1 3.37Å; T330-I334 PolarHBondContact O-N 3.35Å; T330-I334 VanDerWaalsContact O-N 3.12Å; L331-I334 HydrophobicContact CD1-CD1 4.29Å; L331-I334 PolarHBondContact O-N 2.59Å; I334-L336 PolarHBondContact O-N 3.49Å; I334-V339 HydrophobicContact CG2-CB 4.24Å; I334-V339 PolarHBondContact O-N 2.69Å
335	P	63.1	Low	68.6	Low	40 Å²	40	48 Å²	48	26%	0.26	26%	0.258	S	S	.	.	H	α-helix	trans	-60.6	-35.2	173.1	-22.2	32	0	0	0	111.3	L331 G338 Q367 V370	L331-P335 WeakPolarHBondContact O-CD 3.24Å; P335-G338 PolarHBondContact O-N 3.31Å; P335-Q367 WeakPolarHBondContact O-CG 3.36Å; P335-Q367 PolarHBondContact O-NE2 3.07Å; P335-V370 HydrophobicContact CB-CG1 4.3Å; P335-V370 HydrophobicContact CG-CG1 4.43Å
336	L	66.4	Low	68.5	Low	3 Å²	3	44.7 Å²	44.7	2%	0.016	26%	0.255	C	S	.	.	H	α-helix	trans	-62.9	-50.3	-176.7	-175.4	74.4	0	0	0	111.9	L165 L220 L333 I334 G338 Q367 V371 Y375	L165-L336 HydrophobicContact CD2-CD1 4.49Å; L220-L336 WeakPolarHBondContact CD2-O 3.03Å; L333-L336 HydrophobicContact CD1-CD2 3.68Å; L333-L336 WeakPolarHBondContact O-CB 3.46Å; L333-L336 PolarHBondContact O-N 3.43Å; I334-L336 PolarHBondContact O-N 3.49Å; L336-G338 PolarHBondContact O-N 3.46Å; L336-Q367 PolarHBondContact O-NE2 2.69Å; L336-V371 HydrophobicContact CD1-CB 4.22Å; L336-V371 HydrophobicContact CD1-CG1 4.04Å; L336-V371 HydrophobicContact CD1-CG2 3.41Å; L336-V371 VanDerWaalsContact CD1-CG2 3.41Å; L336-Y375 HydrophobicContact CD1-CD2 4.45Å; L336-Y375 HydrophobicContact CD1-CE2 3.62Å; L336-Y375 HydrophobicContact CD2-CE2 3.74Å; L336-Y375 WeakPolarHBondContact CD2-OH 3.09Å; L336-Y375 HydrophobicContact CG-CE2 4.33Å
337	F	68.4	Low	68.7	Low	3 Å²	3	49.6 Å²	49.6	1%	0.013	28%	0.276	C	S	.	.	T	Hydrogen-bonded Turn	trans	-80.5	4.8	-177.4	-70.5	-54.6	0	0	0	115	G224 L227 F299 I302 L333 V339	G224-F337 VanDerWaalsContact CA-CE1 3.45Å; L227-F337 HydrophobicContact CD2-CZ 4.25Å; F299-F337 HydrophobicContact CB-CB 4.46Å; F299-F337 HydrophobicContact CB-CD2 3.92Å; F299-F337 HydrophobicContact CB-CE2 4.44Å; F299-F337 HydrophobicContact CB-CG 4.35Å; F299-F337 AromaticContact CD2-CD2 3.4Å; F299-F337 HydrophobicContact CD2-CD2 3.4Å; F299-F337 AromaticContact CD2-CE2 3.84Å; F299-F337 HydrophobicContact CD2-CE2 3.84Å; F299-F337 HydrophobicContact CD2-CG 4.45Å; F299-F337 HydrophobicContact CE2-CD2 4.25Å; F299-F337 HydrophobicContact CG-CD2 4.02Å; I302-F337 HydrophobicContact CD1-CE2 4.35Å; I302-F337 HydrophobicContact CD1-CZ 3.98Å; L333-F337 HydrophobicContact CD1-CD2 4.23Å; L333-F337 HydrophobicContact CD1-CE2 3.6Å; L333-F337 HydrophobicContact CD1-CZ 4.06Å; L333-F337 HydrophobicContact CD2-CD2 4.15Å; L333-F337 HydrophobicContact CD2-CE2 3.49Å; L333-F337 VanDerWaalsContact CD2-CE2 3.49Å; L333-F337 HydrophobicContact CD2-CZ 4.44Å; L333-F337 HydrophobicContact CG-CD2 3.61Å; L333-F337 HydrophobicContact CG-CE2 3.25Å; L333-F337 HydrophobicContact CG-CZ 4.2Å; L333-F337 WeakPolarHBondContact O-CD2 3.32Å; L333-F337 PolarHBondContact O-N 3.22Å; L333-F337 VanDerWaalsContact O-N 3.08Å; F337-V339 HydrophobicContact CB-CG2 4Å; F337-V339 PolarHBondContact O-N 3.3Å
338	G	67.7	Low	68.5	Low	2 Å²	2	51.4 Å²	51.4	2%	0.021	28%	0.283	C	S	.	.	T	Hydrogen-bonded Turn	trans	66	25	-178.6	0	0	0	0	0	112.8	P335 L336 H340 Y341	P335-G338 PolarHBondContact O-N 3.31Å; L336-G338 PolarHBondContact O-N 3.46Å; G338-H340 PolarHBondContact O-N 3.46Å; G338-Y341 WeakPolarHBondContact O-CB 3.33Å; G338-Y341 WeakPolarHBondContact O-CD2 3.5Å; G338-Y341 PolarHBondContact O-N 3.33Å
339	V	71.4	Confident	67.6	Low	14 Å²	14	49 Å²	49	9%	0.085	28%	0.276	C	S	.	.	H	α-helix	trans	-59.6	-29.8	179.6	176.5	0	0	0	0	111.1	F296 F299 I334 F337 Y341 M342 V343	F296-V339 HydrophobicContact CD2-CB 4.45Å; F296-V339 HydrophobicContact CD2-CG1 3.79Å; F296-V339 HydrophobicContact CD2-CG2 4.15Å; F296-V339 HydrophobicContact CE2-CG1 3.73Å; F299-V339 HydrophobicContact CB-CG2 4.48Å; F299-V339 HydrophobicContact CD1-CG2 3.84Å; F299-V339 HydrophobicContact CE1-CG2 4.19Å; F299-V339 HydrophobicContact CG-CG2 4.09Å; I334-V339 HydrophobicContact CG2-CB 4.24Å; I334-V339 PolarHBondContact O-N 2.69Å; F337-V339 HydrophobicContact CB-CG2 4Å; F337-V339 PolarHBondContact O-N 3.3Å; V339-Y341 PolarHBondContact O-N 3.07Å; V339-M342 WeakPolarHBondContact O-CB 3.31Å; V339-M342 PolarHBondContact O-N 2.91Å; V339-V343 PolarHBondContact O-N 3.22Å
340	H	75.9	Confident	66.8	Low	16 Å²	16	51.7 Å²	51.7	7%	0.074	30%	0.295	C	S	.	.	H	α-helix	trans	-56.9	-36.2	173.1	60.3	-82.8	0	0	0	112.4	G338 M342 V343 F344 F359 L363	G338-H340 PolarHBondContact O-N 3.46Å; H340-M342 VanDerWaalsContact C-N 3.34Å; H340-M342 PolarHBondContact O-N 2.84Å; H340-V343 PolarHBondContact O-N 3.49Å; H340-F344 WeakPolarHBondContact O-CD2 3.27Å; H340-F359 HydrophobicContact CB-CE1 4.21Å; H340-L363 HydrophobicContact CB-CD1 4.45Å
341	Y	71.7	Confident	66.2	Low	9 Å²	9	55.2 Å²	55.2	4%	0.035	31%	0.312	C	S	.	.	H	α-helix	trans	-65.6	-34.1	175.5	-60.3	-78	0	0	0	112.5	R172 F217 I292 G338 V339 F344 A345 E360 Q367	R172-Y341 PolarHBondContact NH1-OH 3.45Å; R172-Y341 PolarHBondContact NH2-OH 3.43Å; F217-Y341 AromaticContact CE1-CD2 3.8Å; F217-Y341 HydrophobicContact CE1-CD2 3.8Å; F217-Y341 AromaticContact CE1-CE2 3.79Å; F217-Y341 HydrophobicContact CE1-CE2 3.79Å; F217-Y341 HydrophobicContact CE1-CG 4.23Å; F217-Y341 HydrophobicContact CZ-CD1 4.34Å; F217-Y341 HydrophobicContact CZ-CD2 4.3Å; F217-Y341 HydrophobicContact CZ-CE1 4.09Å; F217-Y341 HydrophobicContact CZ-CE2 4.08Å; F217-Y341 HydrophobicContact CZ-CG 4.46Å; F217-Y341 AromaticContact CZ-CZ 3.99Å; I292-Y341 HydrophobicContact CD1-CG 4.45Å; G338-Y341 WeakPolarHBondContact O-CB 3.33Å; G338-Y341 WeakPolarHBondContact O-CD2 3.5Å; G338-Y341 PolarHBondContact O-N 3.33Å; V339-Y341 PolarHBondContact O-N 3.07Å; Y341-F344 PolarHBondContact O-N 2.83Å; Y341-A345 VanDerWaalsContact O-CB 3.24Å; Y341-A345 WeakPolarHBondContact O-CB 3.31Å; Y341-A345 PolarHBondContact O-N 3.42Å; Y341-E360 HydrophobicContact CD1-CG 3.84Å; Y341-E360 HydrophobicContact CE1-CG 3.56Å; Y341-Q367 PolarHBondContact OH-OE1 2.04Å
342	M	71.7	Confident	65.8	Low	14 Å²	14	52 Å²	52	7%	0.069	30%	0.299	C	S	.	.	H	α-helix	trans	-64	-39.9	174.8	-78.7	-68.7	90.3	0	0	112.5	I292 I293 F296 V339 H340 F344 A345 V346	I292-M342 HydrophobicContact CB-CE 3.51Å; I292-M342 HydrophobicContact CG2-CE 3.14Å; I292-M342 HydrophobicContact CG2-CG 3.6Å; I292-M342 HydrophobicContact CG2-SD 3.92Å; I293-M342 HydrophobicContact CB-SD 4.4Å; I293-M342 HydrophobicContact CG1-CE 3.74Å; I293-M342 HydrophobicContact CG1-SD 3.73Å; F296-M342 HydrophobicContact CB-CG 3.78Å; F296-M342 HydrophobicContact CB-SD 4.36Å; F296-M342 HydrophobicContact CD2-CB 4.5Å; F296-M342 HydrophobicContact CD2-CG 4.19Å; F296-M342 HydrophobicContact CG-CG 4Å; V339-M342 WeakPolarHBondContact O-CB 3.31Å; V339-M342 PolarHBondContact O-N 2.91Å; H340-M342 VanDerWaalsContact C-N 3.34Å; H340-M342 PolarHBondContact O-N 2.84Å; M342-F344 VanDerWaalsContact C-N 3.3Å; M342-F344 PolarHBondContact O-N 2.95Å; M342-A345 HydrophobicContact CE-CB 4.14Å; M342-A345 PolarHBondContact O-N 2.87Å; M342-V346 WeakPolarHBondContact O-CB 3.2Å; M342-V346 WeakPolarHBondContact O-CG2 3.44Å; M342-V346 PolarHBondContact O-N 2.95Å
343	V	71.3	Confident	65.6	Low	75 Å²	75	53.1 Å²	53.1	46%	0.455	31%	0.312	S	S	.	.	H	α-helix	trans	-59.9	-44.8	-178.7	178.7	0	0	0	0	110	V339 H340 F347	V339-V343 PolarHBondContact O-N 3.22Å; H340-V343 PolarHBondContact O-N 3.49Å; V343-F347 HydrophobicContact CG1-CD2 4.43Å; V343-F347 VanDerWaalsContact O-CB 3.3Å; V343-F347 WeakPolarHBondContact O-CB 3.3Å; V343-F347 WeakPolarHBondContact O-CD2 2.99Å; V343-F347 PolarHBondContact O-N 3.05Å
344	F	68.1	Low	65.3	Low	47 Å²	47	55.4 Å²	55.4	21%	0.206	32%	0.321	C	S	.	.	H	α-helix	trans	-77.3	-28.3	176.8	-62	-75	0	0	0	114.1	H340 Y341 M342 F347 Q356 F359	H340-F344 WeakPolarHBondContact O-CD2 3.27Å; Y341-F344 PolarHBondContact O-N 2.83Å; M342-F344 VanDerWaalsContact C-N 3.3Å; M342-F344 PolarHBondContact O-N 2.95Å; F344-F347 CarbonylContact O-C 3.05Å; F344-Q356 HydrophobicContact CB-CG 4.11Å; F344-Q356 HydrophobicContact CD1-CB 4.29Å; F344-Q356 HydrophobicContact CD1-CG 3.91Å; F344-Q356 HydrophobicContact CG-CG 4.13Å; F344-F359 HydrophobicContact CD2-CD1 4.16Å; F344-F359 HydrophobicContact CE1-CD1 4.43Å; F344-F359 HydrophobicContact CE2-CB 4.41Å; F344-F359 AromaticContact CE2-CD1 3.04Å; F344-F359 HydrophobicContact CE2-CD1 3.04Å; F344-F359 AromaticContact CE2-CE1 3.29Å; F344-F359 HydrophobicContact CE2-CE1 3.29Å; F344-F359 AromaticContact CE2-CG 3.95Å; F344-F359 HydrophobicContact CE2-CG 3.95Å; F344-F359 HydrophobicContact CE2-CZ 4.37Å; F344-F359 HydrophobicContact CZ-CB 3.96Å; F344-F359 AromaticContact CZ-CD1 3.2Å; F344-F359 HydrophobicContact CZ-CD1 3.2Å; F344-F359 HydrophobicContact CZ-CD2 4.42Å; F344-F359 AromaticContact CZ-CE1 3.57Å; F344-F359 HydrophobicContact CZ-CE1 3.57Å; F344-F359 AromaticContact CZ-CG 3.62Å; F344-F359 HydrophobicContact CZ-CG 3.62Å; F344-F359 HydrophobicContact CZ-CZ 4.33Å
345	A	66.9	Low	65.3	Low	40 Å²	40	59.6 Å²	59.6	33%	0.331	33%	0.334	S	S	.	.	H	α-helix	trans	-70.1	-38.1	176.4	0	0	0	0	0	112.5	L289 Y341 M342	L289-A345 HydrophobicContact CD2-CB 4.1Å; Y341-A345 VanDerWaalsContact O-CB 3.24Å; Y341-A345 WeakPolarHBondContact O-CB 3.31Å; Y341-A345 PolarHBondContact O-N 3.42Å; M342-A345 HydrophobicContact CE-CB 4.14Å; M342-A345 PolarHBondContact O-N 2.87Å
346	V	65.9	Low	65.6	Low	95 Å²	95	60.2 Å²	60.2	58%	0.576	33%	0.334	S	S	*	.	H	α-helix	trans	-87.4	-35.9	-178.7	176.3	0	0	0	0	111.8	M342 P348	M342-V346 WeakPolarHBondContact O-CB 3.2Å; M342-V346 WeakPolarHBondContact O-CG2 3.44Å; M342-V346 PolarHBondContact O-N 2.95Å; V346-P348 WeakPolarHBondContact O-CD 3.46Å
347	F	64.8	Low	65.8	Low	124 Å²	124	63.2 Å²	63.2	54%	0.544	35%	0.349	S	S	.	.			trans	-110.6	79.6	177.2	-57.4	-83.6	0	0	0	109.4	V343 F344 I349	V343-F347 HydrophobicContact CG1-CD2 4.43Å; V343-F347 VanDerWaalsContact O-CB 3.3Å; V343-F347 WeakPolarHBondContact O-CB 3.3Å; V343-F347 WeakPolarHBondContact O-CD2 2.99Å; V343-F347 PolarHBondContact O-N 3.05Å; F344-F347 CarbonylContact O-C 3.05Å; F347-I349 HydrophobicContact CB-CD1 4.08Å; F347-I349 HydrophobicContact CB-CG1 3.68Å; F347-I349 PolarHBondContact O-N 3.39Å
348	P	59.6	Low	66	Low	98 Å²	98	65.3 Å²	65.3	64%	0.636	36%	0.36	S	S	*	.			trans	-70.6	67.2	159.3	33.4	-33.2	0	0	0	107.1	V346 S350	V346-P348 WeakPolarHBondContact O-CD 3.46Å; P348-S350 PolarHBondContact O-N 2.9Å
349	I	54.1	Low	66.5	Low	96 Å²	96	69.6 Å²	69.6	49%	0.492	38%	0.378	S	S	.	.			trans	-62.8	131.8	174	-48.8	172.7	0	0	0	104.4	F347 I351	F347-I349 HydrophobicContact CB-CD1 4.08Å; F347-I349 HydrophobicContact CB-CG1 3.68Å; F347-I349 PolarHBondContact O-N 3.39Å; I349-I351 HydrophobicContact CB-CD1 3.89Å; I349-I351 HydrophobicContact CB-CG1 4.13Å; I349-I351 HydrophobicContact CD1-CD1 4.21Å; I349-I351 HydrophobicContact CG2-CD1 3.59Å; I349-I351 HydrophobicContact CG2-CG1 3.65Å; I349-I351 PolarHBondContact O-N 3.45Å
350	S	51.1	Low	66.8	Low	126 Å²	126	72.2 Å²	72.2	88%	0.881	39%	0.39	S	S	*	.	S	Bend	trans	-54.7	9.4	176.4	50	0	0	0	0	115.4	P348 S352	P348-S350 PolarHBondContact O-N 2.9Å; S350-S352 PolarHBondContact O-N 3.19Å
351	I	53.3	Low	67	Low	100 Å²	100	74.3 Å²	74.3	51%	0.513	40%	0.401	S	S	.	.	S	Bend	trans	-61	116.1	164.5	-59.3	163.1	0	0	0	106.8	I349 S353 Y355	I349-I351 HydrophobicContact CB-CD1 3.89Å; I349-I351 HydrophobicContact CB-CG1 4.13Å; I349-I351 HydrophobicContact CD1-CD1 4.21Å; I349-I351 HydrophobicContact CG2-CD1 3.59Å; I349-I351 HydrophobicContact CG2-CG1 3.65Å; I349-I351 PolarHBondContact O-N 3.45Å; I351-S353 PolarHBondContact O-N 3.43Å; I351-Y355 HydrophobicContact CG2-CD2 3.66Å; I351-Y355 HydrophobicContact CG2-CE2 4.43Å; I351-Y355 HydrophobicContact CG2-CG 4.22Å
352	S	59.4	Low	67.5	Low	51 Å²	51	74.8 Å²	74.8	36%	0.357	41%	0.405	S	S	.	.			trans	-21.4	122.8	-176.2	-169.3	0	0	0	0	113.6	S350 K354 Y355	S350-S352 PolarHBondContact O-N 3.19Å; S352-K354 CarbonylContact O-C 3.59Å; S352-K354 PolarHBondContact O-N 3.11Å; S352-K354 WeakPolarHBondContact OG-CG 3.35Å; S352-Y355 PolarHBondContact O-N 3.02Å
353	S	64.5	Low	68	Low	82 Å²	82	77.6 Å²	77.6	57%	0.573	42%	0.42	S	S	*	.	H	α-helix	trans	-42.8	-27.3	175.9	51.6	0	0	0	0	113.6	I351 Q356 I357	I351-S353 PolarHBondContact O-N 3.43Å; S353-Q356 PolarHBondContact O-N 3.49Å; S353-I357 WeakPolarHBondContact O-CD1 3.05Å; S353-I357 VanDerWaalsContact O-CG1 3.3Å; S353-I357 WeakPolarHBondContact O-CG1 3.03Å; S353-I357 PolarHBondContact O-N 2.99Å; S353-I357 VanDerWaalsContact O-N 3.08Å
354	K	66.3	Low	68.7	Low	69 Å²	69	74 Å²	74	30%	0.3	40%	0.399	S	S	.	.	H	α-helix	trans	-52.4	-48.7	170.5	-60.6	-178	-178	-179.8	0	113.9	F122 S352 I357 L358	F122-K354 HydrophobicContact CE1-CB 3.97Å; F122-K354 HydrophobicContact CE1-CG 4.36Å; F122-K354 HydrophobicContact CZ-CB 3.88Å; S352-K354 CarbonylContact O-C 3.59Å; S352-K354 PolarHBondContact O-N 3.11Å; S352-K354 WeakPolarHBondContact OG-CG 3.35Å; K354-I357 PolarHBondContact O-N 2.82Å; K354-L358 WeakPolarHBondContact O-CB 3.41Å; K354-L358 PolarHBondContact O-N 3.28Å
355	Y	69.2	Low	69.8	Low	147 Å²	147	71.8 Å²	71.8	58%	0.576	39%	0.389	S	S	*	.	H	α-helix	trans	-71.4	-35.8	-177.6	-67.3	-71.1	0	0	0	112.4	I351 S352 L358 F359	I351-Y355 HydrophobicContact CG2-CD2 3.66Å; I351-Y355 HydrophobicContact CG2-CE2 4.43Å; I351-Y355 HydrophobicContact CG2-CG 4.22Å; S352-Y355 PolarHBondContact O-N 3.02Å; Y355-L358 PolarHBondContact O-N 3.49Å; Y355-F359 WeakPolarHBondContact O-CB 3.47Å; Y355-F359 PolarHBondContact O-N 3.23Å
356	Q	70.4	Confident	70.9	Confident	54 Å²	54	73.1 Å²	73.1	25%	0.252	39%	0.388	S	S	.	.	H	α-helix	trans	-61.5	-50.1	174.2	177.4	177.4	-8.4	0	0	110.4	F344 S353 L358 F359 E360	F344-Q356 HydrophobicContact CB-CG 4.11Å; F344-Q356 HydrophobicContact CD1-CB 4.29Å; F344-Q356 HydrophobicContact CD1-CG 3.91Å; F344-Q356 HydrophobicContact CG-CG 4.13Å; S353-Q356 PolarHBondContact O-N 3.49Å; Q356-L358 PolarHBondContact O-N 2.94Å; Q356-F359 PolarHBondContact O-N 3.04Å; Q356-E360 VanDerWaalsContact O-CB 3.27Å; Q356-E360 WeakPolarHBondContact O-CB 3.39Å; Q356-E360 PolarHBondContact O-N 2.88Å
357	I	69.4	Low	72.1	Confident	66 Å²	66	68.7 Å²	68.7	34%	0.338	36%	0.36	S	S	.	.	H	α-helix	trans	-59.2	-48.3	178	-66.3	164.1	0	0	0	110.1	S353 K354 F359 E360 L361	S353-I357 WeakPolarHBondContact O-CD1 3.05Å; S353-I357 VanDerWaalsContact O-CG1 3.3Å; S353-I357 WeakPolarHBondContact O-CG1 3.03Å; S353-I357 PolarHBondContact O-N 2.99Å; S353-I357 VanDerWaalsContact O-N 3.08Å; K354-I357 PolarHBondContact O-N 2.82Å; I357-F359 PolarHBondContact O-N 2.6Å; I357-E360 PolarHBondContact O-N 3.48Å; I357-L361 WeakPolarHBondContact O-CB 3.35Å; I357-L361 PolarHBondContact O-N 3.42Å
358	L	74.4	Confident	73.4	Confident	47 Å²	47	62.9 Å²	62.9	25%	0.246	34%	0.336	C	S	.	.	H	α-helix	trans	-56	-51	178.2	177.1	70.9	0	0	0	111.4	F122 V126 K354 Y355 Q356 C362	F122-L358 HydrophobicContact CE2-CD2 4.44Å; F122-L358 HydrophobicContact CZ-CB 4.16Å; V126-L358 HydrophobicContact CG2-CD1 3.64Å; K354-L358 WeakPolarHBondContact O-CB 3.41Å; K354-L358 PolarHBondContact O-N 3.28Å; Y355-L358 PolarHBondContact O-N 3.49Å; Q356-L358 PolarHBondContact O-N 2.94Å; L358-C362 VanDerWaalsContact CD1-SG 3.53Å; L358-C362 WeakPolarHBondContact O-CB 3Å; L358-C362 PolarHBondContact O-N 2.87Å; L358-C362 PolarHBondContact O-SG 3Å
359	F	76.3	Confident	75	Confident	91 Å²	91	60.4 Å²	60.4	40%	0.399	32%	0.317	S	S	.	.	H	α-helix	trans	-66.8	-41.5	-176.6	-167.8	-88.9	0	0	0	112.2	H340 F344 Y355 Q356 I357 L363	H340-F359 HydrophobicContact CB-CE1 4.21Å; F344-F359 HydrophobicContact CD2-CD1 4.16Å; F344-F359 HydrophobicContact CE1-CD1 4.43Å; F344-F359 HydrophobicContact CE2-CB 4.41Å; F344-F359 AromaticContact CE2-CD1 3.04Å; F344-F359 HydrophobicContact CE2-CD1 3.04Å; F344-F359 AromaticContact CE2-CE1 3.29Å; F344-F359 HydrophobicContact CE2-CE1 3.29Å; F344-F359 AromaticContact CE2-CG 3.95Å; F344-F359 HydrophobicContact CE2-CG 3.95Å; F344-F359 HydrophobicContact CE2-CZ 4.37Å; F344-F359 HydrophobicContact CZ-CB 3.96Å; F344-F359 AromaticContact CZ-CD1 3.2Å; F344-F359 HydrophobicContact CZ-CD1 3.2Å; F344-F359 HydrophobicContact CZ-CD2 4.42Å; F344-F359 AromaticContact CZ-CE1 3.57Å; F344-F359 HydrophobicContact CZ-CE1 3.57Å; F344-F359 AromaticContact CZ-CG 3.62Å; F344-F359 HydrophobicContact CZ-CG 3.62Å; F344-F359 HydrophobicContact CZ-CZ 4.33Å; Y355-F359 WeakPolarHBondContact O-CB 3.47Å; Y355-F359 PolarHBondContact O-N 3.23Å; Q356-F359 PolarHBondContact O-N 3.04Å; I357-F359 PolarHBondContact O-N 2.6Å; F359-L363 HydrophobicContact CD1-CD1 3.78Å; F359-L363 HydrophobicContact CD1-CG 4.07Å; F359-L363 HydrophobicContact CD2-CD1 4.41Å; F359-L363 HydrophobicContact CD2-CG 4.41Å; F359-L363 HydrophobicContact CE1-CD1 3.14Å; F359-L363 HydrophobicContact CE1-CG 3.92Å; F359-L363 HydrophobicContact CE2-CD1 3.83Å; F359-L363 HydrophobicContact CE2-CG 4.23Å; F359-L363 HydrophobicContact CG-CD1 4.42Å; F359-L363 HydrophobicContact CG-CG 4.38Å; F359-L363 HydrophobicContact CZ-CD1 3.2Å; F359-L363 HydrophobicContact CZ-CG 4.03Å; F359-L363 VanDerWaalsContact O-CB 3.26Å; F359-L363 WeakPolarHBondContact O-CB 3.41Å; F359-L363 WeakPolarHBondContact O-CG 2.97Å; F359-L363 PolarHBondContact O-N 3.21Å
360	E	78	Confident	76.7	Confident	70 Å²	70	57.9 Å²	57.9	33%	0.327	31%	0.306	S	S	.	.	H	α-helix	trans	-65.3	-47.2	179.2	-170.3	176.3	161.2	0	0	111.9	Y341 Q356 I357 G364	Y341-E360 HydrophobicContact CD1-CG 3.84Å; Y341-E360 HydrophobicContact CE1-CG 3.56Å; Q356-E360 VanDerWaalsContact O-CB 3.27Å; Q356-E360 WeakPolarHBondContact O-CB 3.39Å; Q356-E360 PolarHBondContact O-N 2.88Å; I357-E360 PolarHBondContact O-N 3.48Å; E360-G364 WeakPolarHBondContact O-CA 3.35Å; E360-G364 PolarHBondContact O-N 2.85Å
361	L	81.1	Confident	78.6	Confident	59 Å²	59	51.9 Å²	51.9	31%	0.309	26%	0.264	S	S	.	.	H	α-helix	trans	-69.8	-45.4	179.2	-119.2	58.9	0	0	0	111.6	V126 Y130 I357 S365	V126-L361 HydrophobicContact CG1-CD2 4.02Å; Y130-L361 HydrophobicContact CD1-CB 4.47Å; Y130-L361 HydrophobicContact CD1-CD2 3.41Å; Y130-L361 VanDerWaalsContact CD1-CD2 3.41Å; Y130-L361 HydrophobicContact CD1-CG 4Å; Y130-L361 HydrophobicContact CE1-CD2 3.62Å; Y130-L361 HydrophobicContact CG-CD2 4.2Å; Y130-L361 HydrophobicContact CG-CG 4.34Å; I357-L361 WeakPolarHBondContact O-CB 3.35Å; I357-L361 PolarHBondContact O-N 3.42Å; L361-S365 VanDerWaalsContact O-CB 3.26Å; L361-S365 WeakPolarHBondContact O-CB 3.43Å; L361-S365 PolarHBondContact O-N 3.16Å; L361-S365 PolarHBondContact O-OG 2.76Å
362	C	82.2	Confident	80.5	Confident	19 Å²	19	47.1 Å²	47.1	13%	0.128	24%	0.24	C	C	.	.	H	α-helix	trans	-66.2	-55	-179.3	-67.6	0	0	0	0	110.9	I129 L358 G364 S365 F366	I129-C362 HydrophobicContact CG2-CB 4.33Å; I129-C362 WeakPolarHBondContact CG2-SG 3.43Å; L358-C362 VanDerWaalsContact CD1-SG 3.53Å; L358-C362 WeakPolarHBondContact O-CB 3Å; L358-C362 PolarHBondContact O-N 2.87Å; L358-C362 PolarHBondContact O-SG 3Å; C362-G364 VanDerWaalsContact C-N 3.31Å; C362-G364 PolarHBondContact O-N 3.39Å; C362-S365 PolarHBondContact O-N 3.48Å; C362-S365 PolarHBondContact O-OG 2.71Å; C362-F366 VanDerWaalsContact O-CD2 3.25Å; C362-F366 WeakPolarHBondContact O-CD2 3.42Å; C362-F366 PolarHBondContact O-N 3.17Å
363	L	82.8	Confident	82	Confident	73 Å²	73	47 Å²	47	38%	0.382	24%	0.236	S	C	.	.	H	α-helix	trans	-64.4	-37.6	179.5	-70.6	-159	0	0	0	112.5	H340 F359 S365 F366 Q367	H340-L363 HydrophobicContact CB-CD1 4.45Å; F359-L363 HydrophobicContact CD1-CD1 3.78Å; F359-L363 HydrophobicContact CD1-CG 4.07Å; F359-L363 HydrophobicContact CD2-CD1 4.41Å; F359-L363 HydrophobicContact CD2-CG 4.41Å; F359-L363 HydrophobicContact CE1-CD1 3.14Å; F359-L363 HydrophobicContact CE1-CG 3.92Å; F359-L363 HydrophobicContact CE2-CD1 3.83Å; F359-L363 HydrophobicContact CE2-CG 4.23Å; F359-L363 HydrophobicContact CG-CD1 4.42Å; F359-L363 HydrophobicContact CG-CG 4.38Å; F359-L363 HydrophobicContact CZ-CD1 3.2Å; F359-L363 HydrophobicContact CZ-CG 4.03Å; F359-L363 VanDerWaalsContact O-CB 3.26Å; F359-L363 WeakPolarHBondContact O-CB 3.41Å; F359-L363 WeakPolarHBondContact O-CG 2.97Å; F359-L363 PolarHBondContact O-N 3.21Å; L363-S365 VanDerWaalsContact C-N 3.31Å; L363-S365 PolarHBondContact O-N 3.04Å; L363-F366 PolarHBondContact O-N 3Å; L363-Q367 PolarHBondContact O-N 2.9Å
364	G	85.1	Confident	83.1	Confident	1 Å²	1	44.9 Å²	44.9	1%	0.01	22%	0.218	C	C	.	.	H	α-helix	trans	-59.7	-41.3	174.7	0	0	0	0	0	112.2	E360 C362 F366 Q367	E360-G364 WeakPolarHBondContact O-CA 3.35Å; E360-G364 PolarHBondContact O-N 2.85Å; C362-G364 VanDerWaalsContact C-N 3.31Å; C362-G364 PolarHBondContact O-N 3.39Å; G364-F366 PolarHBondContact O-N 3.13Å; G364-Q367 VanDerWaalsContact O-CB 3.29Å; G364-Q367 WeakPolarHBondContact O-CB 3.28Å; G364-Q367 PolarHBondContact O-N 3.38Å
365	S	90.3	Very high	84.2	Confident	0 Å²	0	43.4 Å²	43.4	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-65.7	-35.4	-179.7	72.6	0	0	0	0	113.6	Y130 G133 S137 L361 C362 L363	Y130-S365 WeakPolarHBondContact O-CB 3.43Å; G133-S365 CarbonylContact C-O 3.5Å; S137-S365 WeakPolarHBondContact CB-O 3.27Å; S137-S365 PolarHBondContact OG-O 3.47Å; L361-S365 VanDerWaalsContact O-CB 3.26Å; L361-S365 WeakPolarHBondContact O-CB 3.43Å; L361-S365 PolarHBondContact O-N 3.16Å; L361-S365 PolarHBondContact O-OG 2.76Å; C362-S365 PolarHBondContact O-N 3.48Å; C362-S365 PolarHBondContact O-OG 2.71Å; L363-S365 VanDerWaalsContact C-N 3.31Å; L363-S365 PolarHBondContact O-N 3.04Å
366	F	90.8	Very high	85.2	Confident	68 Å²	68	36.4 Å²	36.4	30%	0.298	18%	0.184	S	C	.	.	H	α-helix	trans	-88.8	-8.1	177	-69.3	-76.8	0	0	0	113.8	I129 C362 L363 G364 G368 L369 V370	I129-F366 HydrophobicContact CG2-CE2 4.34Å; C362-F366 VanDerWaalsContact O-CD2 3.25Å; C362-F366 WeakPolarHBondContact O-CD2 3.42Å; C362-F366 PolarHBondContact O-N 3.17Å; L363-F366 PolarHBondContact O-N 3Å; G364-F366 PolarHBondContact O-N 3.13Å; F366-G368 VanDerWaalsContact C-N 3.26Å; F366-G368 PolarHBondContact O-N 3.06Å; F366-L369 HydrophobicContact CD1-CD2 4.24Å; F366-L369 WeakPolarHBondContact O-CB 3.43Å; F366-L369 PolarHBondContact O-N 3.11Å; F366-L369 VanDerWaalsContact O-N 3.16Å; F366-V370 PolarHBondContact O-N 3.39Å
367	Q	91.2	Very high	86.2	Confident	1 Å²	1	37.2 Å²	37.2	1%	0.005	19%	0.187	C	C	.	.	H	α-helix	trans	-55.9	-43.7	-178.9	-169.7	-179.1	-6.4	0	0	111.1	F169 P335 L336 Y341 L363 G364 L369 V370 V371	F169-Q367 HydrophobicContact CE1-CB 4.12Å; F169-Q367 HydrophobicContact CE1-CG 3.96Å; F169-Q367 HydrophobicContact CZ-CG 3.94Å; P335-Q367 WeakPolarHBondContact O-CG 3.36Å; P335-Q367 PolarHBondContact O-NE2 3.07Å; L336-Q367 PolarHBondContact O-NE2 2.69Å; Y341-Q367 PolarHBondContact OH-OE1 2.04Å; L363-Q367 PolarHBondContact O-N 2.9Å; G364-Q367 VanDerWaalsContact O-CB 3.29Å; G364-Q367 WeakPolarHBondContact O-CB 3.28Å; G364-Q367 PolarHBondContact O-N 3.38Å; Q367-L369 PolarHBondContact O-N 3.19Å; Q367-V370 PolarHBondContact O-N 3.04Å; Q367-V371 WeakPolarHBondContact O-CG2 3.49Å; Q367-V371 PolarHBondContact O-N 2.76Å
368	G	92.3	Very high	87.1	Confident	2 Å²	2	39.1 Å²	39.1	2%	0.021	20%	0.197	C	C	.	.	H	α-helix	trans	-59.4	-41.7	178.2	0	0	0	0	0	113.9	F366 V371 A372	F366-G368 VanDerWaalsContact C-N 3.26Å; F366-G368 PolarHBondContact O-N 3.06Å; G368-V371 PolarHBondContact O-N 2.94Å; G368-A372 PolarHBondContact O-N 2.03Å
369	L	93	Very high	87.7	Confident	47 Å²	47	38.3 Å²	38.3	25%	0.246	19%	0.193	C	C	.	.	H	α-helix	trans	-59.4	-47.1	173.8	173.5	65.5	0	0	0	111.5	V136 S137 S140 F366 Q367 V371 A372 V373	V136-L369 HydrophobicContact CG1-CD1 4.13Å; V136-L369 HydrophobicContact CG1-CD2 3.91Å; S137-L369 PolarHBondContact OG-N 3.27Å; S140-L369 WeakPolarHBondContact OG-CD1 3.36Å; F366-L369 HydrophobicContact CD1-CD2 4.24Å; F366-L369 WeakPolarHBondContact O-CB 3.43Å; F366-L369 PolarHBondContact O-N 3.11Å; F366-L369 VanDerWaalsContact O-N 3.16Å; Q367-L369 PolarHBondContact O-N 3.19Å; L369-V371 VanDerWaalsContact C-N 3.31Å; L369-V371 PolarHBondContact O-N 3.21Å; L369-A372 PolarHBondContact O-N 2.88Å; L369-V373 HydrophobicContact CD1-CG2 4.11Å; L369-V373 HydrophobicContact CG-CG2 4.5Å; L369-V373 VanDerWaalsContact O-CG2 3.29Å; L369-V373 WeakPolarHBondContact O-CG2 3.44Å; L369-V373 PolarHBondContact O-N 2.77Å
370	V	90.5	Very high	88.1	Confident	42 Å²	42	37.9 Å²	37.9	26%	0.255	20%	0.201	S	C	.	.	H	α-helix	trans	-59.8	-44.9	178.2	177.1	0	0	0	0	110.2	P335 F366 Q367 A372 V373 L374	P335-V370 HydrophobicContact CB-CG1 4.3Å; P335-V370 HydrophobicContact CG-CG1 4.43Å; F366-V370 PolarHBondContact O-N 3.39Å; Q367-V370 PolarHBondContact O-N 3.04Å; V370-A372 PolarHBondContact O-N 3.02Å; V370-V373 PolarHBondContact O-N 3.42Å; V370-L374 HydrophobicContact CG1-CD1 3.73Å; V370-L374 HydrophobicContact CG1-CG 4.39Å; V370-L374 VanDerWaalsContact O-CG 3.23Å; V370-L374 WeakPolarHBondContact O-CG 3.4Å; V370-L374 PolarHBondContact O-N 2.94Å
371	V	91.2	Very high	88.6	Confident	1 Å²	1	38.8 Å²	38.8	1%	0.006	21%	0.205	C	C	.	.	H	α-helix	trans	-59.2	-47	176.4	179.7	0	0	0	0	111.4	L165 F166 F169 L336 Q367 G368 L369 L374 Y375	L165-V371 HydrophobicContact CD2-CG1 3.97Å; F166-V371 HydrophobicContact CD1-CG1 4.04Å; F166-V371 HydrophobicContact CE1-CG1 3.71Å; F169-V371 HydrophobicContact CE2-CB 4.45Å; F169-V371 HydrophobicContact CE2-CG1 4.37Å; F169-V371 HydrophobicContact CE2-CG2 3.81Å; F169-V371 HydrophobicContact CZ-CG2 3.99Å; L336-V371 HydrophobicContact CD1-CB 4.22Å; L336-V371 HydrophobicContact CD1-CG1 4.04Å; L336-V371 HydrophobicContact CD1-CG2 3.41Å; L336-V371 VanDerWaalsContact CD1-CG2 3.41Å; Q367-V371 WeakPolarHBondContact O-CG2 3.49Å; Q367-V371 PolarHBondContact O-N 2.76Å; G368-V371 PolarHBondContact O-N 2.94Å; L369-V371 VanDerWaalsContact C-N 3.31Å; L369-V371 PolarHBondContact O-N 3.21Å; V371-L374 PolarHBondContact O-N 3.4Å; V371-Y375 HydrophobicContact CG1-CD2 3.73Å; V371-Y375 HydrophobicContact CG1-CE2 4.22Å; V371-Y375 PolarHBondContact O-N 2.97Å
372	A	92.4	Very high	89	Confident	0 Å²	0	36.2 Å²	36.2	0%	0	19%	0.192	C	C	.	.	H	α-helix	trans	-62.8	-43.5	179.3	0	0	0	0	0	112.3	L141 G368 L369 V370 L374 C376 F377	L141-A372 HydrophobicContact CD2-CB 3.89Å; L141-A372 HydrophobicContact CG-CB 4.17Å; G368-A372 PolarHBondContact O-N 2.03Å; L369-A372 PolarHBondContact O-N 2.88Å; V370-A372 PolarHBondContact O-N 3.02Å; A372-L374 VanDerWaalsContact C-N 3.34Å; A372-L374 PolarHBondContact O-N 3.48Å; A372-C376 WeakPolarHBondContact O-CA 3.5Å; A372-C376 WeakPolarHBondContact O-CB 3.36Å; A372-C376 PolarHBondContact O-N 3.24Å; A372-F377 HydrophobicContact CB-CE2 4.47Å; A372-F377 PolarHBondContact O-N 2.85Å
373	V	91.4	Very high	89.4	Confident	48 Å²	48	40 Å²	40	29%	0.291	21%	0.208	S	C	.	.	I	π-helix	trans	-61.8	-43.5	177.8	170.6	0	0	0	0	110.9	L369 V370 F377 L378	L369-V373 HydrophobicContact CD1-CG2 4.11Å; L369-V373 HydrophobicContact CG-CG2 4.5Å; L369-V373 VanDerWaalsContact O-CG2 3.29Å; L369-V373 WeakPolarHBondContact O-CG2 3.44Å; L369-V373 PolarHBondContact O-N 2.77Å; V370-V373 PolarHBondContact O-N 3.42Å; V373-F377 HydrophobicContact CG2-CD2 4.05Å; V373-F377 PolarHBondContact O-N 3.2Å; V373-L378 HydrophobicContact CG1-CD1 3.67Å; V373-L378 HydrophobicContact CG1-CG 3.81Å; V373-L378 VanDerWaalsContact O-CB 3.3Å; V373-L378 WeakPolarHBondContact O-CB 3.37Å; V373-L378 WeakPolarHBondContact O-CG 3.31Å; V373-L378 PolarHBondContact O-N 3.43Å
374	L	88.1	Confident	89.8	Confident	37 Å²	37	40.4 Å²	40.4	19%	0.194	22%	0.216	C	C	.	.	I	π-helix	trans	-73.5	-50.6	-176.4	-67.5	171.5	0	0	0	113.4	L332 V370 V371 A372 L378	L332-L374 HydrophobicContact CB-CD1 3.75Å; L332-L374 HydrophobicContact CB-CD2 3.78Å; L332-L374 HydrophobicContact CB-CG 4.42Å; L332-L374 HydrophobicContact CD1-CD2 3.56Å; L332-L374 HydrophobicContact CD2-CD1 4.35Å; L332-L374 HydrophobicContact CD2-CD2 3.8Å; L332-L374 HydrophobicContact CG-CD2 3.86Å; L332-L374 VanDerWaalsContact O-CD1 3.31Å; L332-L374 WeakPolarHBondContact O-CD1 3.2Å; V370-L374 HydrophobicContact CG1-CD1 3.73Å; V370-L374 HydrophobicContact CG1-CG 4.39Å; V370-L374 VanDerWaalsContact O-CG 3.23Å; V370-L374 WeakPolarHBondContact O-CG 3.4Å; V370-L374 PolarHBondContact O-N 2.94Å; V371-L374 PolarHBondContact O-N 3.4Å; A372-L374 VanDerWaalsContact C-N 3.34Å; A372-L374 PolarHBondContact O-N 3.48Å; L374-L378 HydrophobicContact CD2-CD1 4.31Å
375	Y	87.3	Confident	90	Very high	38 Å²	38	41.6 Å²	41.6	15%	0.149	22%	0.221	C	C	.	.	I	π-helix	trans	-85.4	-21.9	-172.7	-72.1	-54.4	0	0	0	114	H162 L165 F166 E223 L336 V371 N379	H162-Y375 AromaticContact CE1-CD1 3.52Å; H162-Y375 AromaticContact CE1-CE1 3.41Å; H162-Y375 VanDerWaalsContact CE1-CE1 3.41Å; H162-Y375 WeakPolarHBondContact CE1-CE1 3.41Å; H162-Y375 AromaticContact CE1-CZ 3.8Å; H162-Y375 AromaticContact NE2-CD1 3.55Å; H162-Y375 AromaticContact NE2-CE1 3.81Å; L165-Y375 HydrophobicContact CD2-CE2 4.33Å; F166-Y375 HydrophobicContact CE1-CD2 4.43Å; E223-Y375 PolarHBondContact OE1-OH 2.91Å; L336-Y375 HydrophobicContact CD1-CD2 4.45Å; L336-Y375 HydrophobicContact CD1-CE2 3.62Å; L336-Y375 HydrophobicContact CD2-CE2 3.74Å; L336-Y375 WeakPolarHBondContact CD2-OH 3.09Å; L336-Y375 HydrophobicContact CG-CE2 4.33Å; V371-Y375 HydrophobicContact CG1-CD2 3.73Å; V371-Y375 HydrophobicContact CG1-CE2 4.22Å; V371-Y375 PolarHBondContact O-N 2.97Å; Y375-N379 WeakPolarHBondContact O-CB 3.46Å; Y375-N379 PolarHBondContact O-ND2 2.91Å
376	C	90.8	Very high	89.9	Confident	0 Å²	0	46.1 Å²	46.1	0%	0	25%	0.245	C	C	.	.	I	π-helix	trans	-111	-66.9	178.9	-166.2	0	0	0	0	112.4	G144 F166 A372 N379 V382	G144-C376 WeakPolarHBondContact CA-SG 3.47Å; F166-C376 HydrophobicContact CE2-CB 4.22Å; F166-C376 HydrophobicContact CZ-CB 4.28Å; A372-C376 WeakPolarHBondContact O-CA 3.5Å; A372-C376 WeakPolarHBondContact O-CB 3.36Å; A372-C376 PolarHBondContact O-N 3.24Å; C376-N379 WeakPolarHBondContact O-CB 3.49Å; C376-N379 PolarHBondContact O-N 2.85Å; C376-V382 WeakPolarHBondContact O-CB 3.23Å
377	F	91.4	Very high	89.9	Confident	72 Å²	72	48.7 Å²	48.7	32%	0.316	26%	0.256	S	S	.	.	I	π-helix	trans	-72.7	-35.5	-166.2	-58.4	-44.7	0	0	0	114.5	T143 I147 A372 V373 Q383	T143-F377 HydrophobicContact CG2-CE1 4.23Å; T143-F377 HydrophobicContact CG2-CZ 4.21Å; I147-F377 HydrophobicContact CD1-CD1 4.49Å; I147-F377 HydrophobicContact CD1-CE1 3.94Å; A372-F377 HydrophobicContact CB-CE2 4.47Å; A372-F377 PolarHBondContact O-N 2.85Å; V373-F377 HydrophobicContact CG2-CD2 4.05Å; V373-F377 PolarHBondContact O-N 3.2Å; F377-Q383 WeakPolarHBondContact O-CG 3.49Å; F377-Q383 PolarHBondContact O-NE2 2.74Å
378	L	88.2	Confident	89.8	Confident	105 Å²	105	54.3 Å²	54.3	55%	0.55	28%	0.277	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.3	-2.1	176.3	-65	-178.2	0	0	0	113.2	V373 L374 S380	V373-L378 HydrophobicContact CG1-CD1 3.67Å; V373-L378 HydrophobicContact CG1-CG 3.81Å; V373-L378 VanDerWaalsContact O-CB 3.3Å; V373-L378 WeakPolarHBondContact O-CB 3.37Å; V373-L378 WeakPolarHBondContact O-CG 3.31Å; V373-L378 PolarHBondContact O-N 3.43Å; L374-L378 HydrophobicContact CD2-CD1 4.31Å; L378-S380 PolarHBondContact O-N 2.86Å
379	N	87.5	Confident	89.6	Confident	31 Å²	31	59.1 Å²	59.1	17%	0.166	30%	0.297	C	S	.	.			trans	-73	120	179.3	-172.2	-26.4	0	0	0	110	Y375 C376 E381 V382 Q383	Y375-N379 WeakPolarHBondContact O-CB 3.46Å; Y375-N379 PolarHBondContact O-ND2 2.91Å; C376-N379 WeakPolarHBondContact O-CB 3.49Å; C376-N379 PolarHBondContact O-N 2.85Å; N379-E381 VanDerWaalsContact C-N 3.26Å; N379-E381 PolarHBondContact O-N 2.87Å; N379-E381 WeakPolarHBondContact OD1-CB 3.43Å; N379-E381 PolarHBondContact OD1-N 3.36Å; N379-E381 VanDerWaalsContact OD1-N 3.08Å; N379-V382 HydrophobicContact CB-CB 4.19Å; N379-V382 HydrophobicContact CB-CG2 3.79Å; N379-V382 WeakPolarHBondContact O-CB 3.3Å; N379-V382 PolarHBondContact O-N 2.83Å; N379-V382 VanDerWaalsContact O-N 3.12Å; N379-Q383 WeakPolarHBondContact O-CG 3.46Å; N379-Q383 PolarHBondContact O-N 2.87Å
380	S	85.6	Confident	89.4	Confident	81 Å²	81	65.4 Å²	65.4	57%	0.566	32%	0.318	S	S	*	.	H	α-helix	trans	-61.4	-33.5	-176.5	56.7	0	0	0	0	112.6	L378 Q383 C384	L378-S380 PolarHBondContact O-N 2.86Å; S380-Q383 PolarHBondContact O-N 2.86Å; S380-C384 WeakPolarHBondContact O-CB 3.49Å; S380-C384 PolarHBondContact O-N 3.27Å; S380-C384 PolarHBondContact O-SG 3.22Å
381	E	88.5	Confident	89.2	Confident	90 Å²	90	71 Å²	71	42%	0.421	33%	0.334	S	S	.	.	H	α-helix	trans	-63.7	-44.5	176	-63.7	179.3	-173	0	0	110.8	L154 N379 C384 E385	L154-E381 HydrophobicContact CD2-CB 4.14Å; N379-E381 VanDerWaalsContact C-N 3.26Å; N379-E381 PolarHBondContact O-N 2.87Å; N379-E381 WeakPolarHBondContact OD1-CB 3.43Å; N379-E381 PolarHBondContact OD1-N 3.36Å; N379-E381 VanDerWaalsContact OD1-N 3.08Å; E381-C384 PolarHBondContact O-N 3.38Å; E381-E385 WeakPolarHBondContact O-CB 3.41Å; E381-E385 WeakPolarHBondContact O-CG 3.47Å; E381-E385 PolarHBondContact O-N 2.72Å
382	V	88.8	Confident	89	Confident	5 Å²	5	74.7 Å²	74.7	3%	0.03	36%	0.36	C	S	.	.	H	α-helix	trans	-65.9	-45.9	178.2	-178.5	0	0	0	0	110.5	I147 L148 L154 C376 N379 C384 E385 L386	I147-V382 HydrophobicContact CG2-CG1 3.67Å; L148-V382 HydrophobicContact CD2-CG2 4.09Å; L154-V382 HydrophobicContact CD1-CG2 3.98Å; C376-V382 WeakPolarHBondContact O-CB 3.23Å; N379-V382 HydrophobicContact CB-CB 4.19Å; N379-V382 HydrophobicContact CB-CG2 3.79Å; N379-V382 WeakPolarHBondContact O-CB 3.3Å; N379-V382 PolarHBondContact O-N 2.83Å; N379-V382 VanDerWaalsContact O-N 3.12Å; V382-C384 VanDerWaalsContact C-N 3.33Å; V382-C384 PolarHBondContact O-N 3.35Å; V382-E385 PolarHBondContact O-N 2.82Å; V382-L386 WeakPolarHBondContact O-CB 3.2Å; V382-L386 PolarHBondContact O-N 3.15Å
383	Q	90.7	Very high	88.5	Confident	99 Å²	99	84.1 Å²	84.1	46%	0.463	40%	0.396	S	S	.	.	H	α-helix	trans	-61.4	-41.2	177.1	-69.6	-175.9	6	0	0	112	F377 N379 S380 L386 K387	F377-Q383 WeakPolarHBondContact O-CG 3.49Å; F377-Q383 PolarHBondContact O-NE2 2.74Å; N379-Q383 WeakPolarHBondContact O-CG 3.46Å; N379-Q383 PolarHBondContact O-N 2.87Å; S380-Q383 PolarHBondContact O-N 2.86Å; Q383-L386 PolarHBondContact O-N 3.44Å; Q383-K387 WeakPolarHBondContact O-CB 2.99Å; Q383-K387 PolarHBondContact O-N 2.64Å
384	C	90	Very high	87.7	Confident	81 Å²	81	85.2 Å²	85.2	55%	0.547	41%	0.405	S	S	.	.	H	α-helix	trans	-62.2	-45.6	176.1	-73	0	0	0	0	111.7	S380 E381 V382 K387 R388	S380-C384 WeakPolarHBondContact O-CB 3.49Å; S380-C384 PolarHBondContact O-N 3.27Å; S380-C384 PolarHBondContact O-SG 3.22Å; E381-C384 PolarHBondContact O-N 3.38Å; V382-C384 VanDerWaalsContact C-N 3.33Å; V382-C384 PolarHBondContact O-N 3.35Å; C384-K387 PolarHBondContact O-N 2.85Å; C384-R388 VanDerWaalsContact O-CB 3.28Å; C384-R388 WeakPolarHBondContact O-CB 3.01Å; C384-R388 PolarHBondContact O-N 2.94Å
385	E	90.1	Very high	86.1	Confident	26 Å²	26	88.1 Å²	88.1	12%	0.121	43%	0.426	C	S	.	.	H	α-helix	trans	-67.4	-40.1	178.8	-76.2	-62.3	147.9	0	0	112.5	K153 L154 E381 V382 R388 K389	K153-E385 VanDerWaalsContact CD-OE1 3.3Å; K153-E385 WeakPolarHBondContact CD-OE1 3.3Å; K153-E385 IonicContact NZ-OE1 3.45Å; L154-E385 HydrophobicContact CD2-CG 4.29Å; E381-E385 WeakPolarHBondContact O-CB 3.41Å; E381-E385 WeakPolarHBondContact O-CG 3.47Å; E381-E385 PolarHBondContact O-N 2.72Å; V382-E385 PolarHBondContact O-N 2.82Å; E385-R388 WeakPolarHBondContact O-CB 3.22Å; E385-R388 PolarHBondContact O-N 2.77Å; E385-R388 IonicContact OE1-CZ 3.17Å; E385-R388 IonicContact OE1-NE 3.22Å; E385-R388 PolarHBondContact OE1-NE 3.43Å; E385-R388 IonicContact OE1-NH2 2.64Å; E385-R388 PolarHBondContact OE1-NH2 3.47Å; E385-R388 IonicContact OE2-CZ 3.8Å; E385-R388 IonicContact OE2-NE 2.93Å; E385-R388 PolarHBondContact OE2-NE 2.03Å; E385-R388 IonicContact OE2-NH2 2.64Å; E385-R388 PolarHBondContact OE2-NH2 3.36Å; E385-K389 PolarHBondContact O-N 3.42Å
386	L	88.9	Confident	84.6	Confident	94 Å²	94	92.3 Å²	92.3	49%	0.492	46%	0.455	S	S	.	.	H	α-helix	trans	-64.2	-46.4	174.4	-173.5	62.2	0	0	0	111	V382 Q383 R388 K389 W390	V382-L386 WeakPolarHBondContact O-CB 3.2Å; V382-L386 PolarHBondContact O-N 3.15Å; Q383-L386 PolarHBondContact O-N 3.44Å; L386-R388 VanDerWaalsContact C-N 3.27Å; L386-R388 PolarHBondContact O-N 2.89Å; L386-K389 PolarHBondContact O-N 2.91Å; L386-W390 WeakPolarHBondContact O-CB 3.25Å; L386-W390 PolarHBondContact O-N 3.38Å
387	K	89.9	Confident	82.4	Confident	122 Å²	122	97.9 Å²	97.9	53%	0.53	49%	0.492	S	S	.	.	H	α-helix	trans	-60.7	-37	175	-173.4	176.3	-176.7	173.7	0	111.8	Q383 C384 R391	Q383-K387 WeakPolarHBondContact O-CB 2.99Å; Q383-K387 PolarHBondContact O-N 2.64Å; C384-K387 PolarHBondContact O-N 2.85Å; K387-R391 WeakPolarHBondContact O-CB 3.25Å; K387-R391 WeakPolarHBondContact O-CG 3.34Å; K387-R391 PolarHBondContact O-N 3.06Å
388	R	89.4	Confident	79.9	Confident	119 Å²	119	99.6 Å²	99.6	45%	0.449	51%	0.513	S	S	.	.	H	α-helix	trans	-66	-45.3	175.9	-171.2	171.5	75.1	111.4	8.5	111.5	K153 C384 E385 L386 S392	K153-R388 VanDerWaalsContact CE-NH2 3.29Å; K153-R388 VanDerWaalsContact NZ-CZ 3.32Å; C384-R388 VanDerWaalsContact O-CB 3.28Å; C384-R388 WeakPolarHBondContact O-CB 3.01Å; C384-R388 PolarHBondContact O-N 2.94Å; E385-R388 WeakPolarHBondContact O-CB 3.22Å; E385-R388 PolarHBondContact O-N 2.77Å; E385-R388 IonicContact OE1-CZ 3.17Å; E385-R388 IonicContact OE1-NE 3.22Å; E385-R388 PolarHBondContact OE1-NE 3.43Å; E385-R388 IonicContact OE1-NH2 2.64Å; E385-R388 PolarHBondContact OE1-NH2 3.47Å; E385-R388 IonicContact OE2-CZ 3.8Å; E385-R388 IonicContact OE2-NE 2.93Å; E385-R388 PolarHBondContact OE2-NE 2.03Å; E385-R388 IonicContact OE2-NH2 2.64Å; E385-R388 PolarHBondContact OE2-NH2 3.36Å; L386-R388 VanDerWaalsContact C-N 3.27Å; L386-R388 PolarHBondContact O-N 2.89Å; R388-S392 PolarHBondContact O-N 2.99Å; R388-S392 VanDerWaalsContact O-N 3.14Å
389	K	87.4	Confident	77.7	Confident	104 Å²	104	99.9 Å²	99.9	45%	0.452	53%	0.53	S	S	.	.	H	α-helix	trans	-68.8	-37.7	177.7	-166.2	69.1	174.6	-175.5	0	112.1	F151 E385 L386 S392 R393	F151-K389 HydrophobicContact CE1-CB 3.98Å; F151-K389 HydrophobicContact CE1-CD 4.4Å; F151-K389 HydrophobicContact CE1-CG 4.11Å; F151-K389 HydrophobicContact CZ-CB 4.22Å; F151-K389 HydrophobicContact CZ-CG 4.37Å; E385-K389 PolarHBondContact O-N 3.42Å; L386-K389 PolarHBondContact O-N 2.91Å; K389-S392 WeakPolarHBondContact CA-OG 3.35Å; K389-S392 PolarHBondContact O-N 3.17Å; K389-S392 PolarHBondContact O-OG 2.91Å; K389-R393 PolarHBondContact O-N 2.83Å; K389-R393 VanDerWaalsContact O-N 3.09Å
390	W	88.6	Confident	75.2	Confident	179 Å²	179	103.5 Å²	103.5	68%	0.678	56%	0.558	S	S	*	*	H	α-helix	trans	-64.2	-45.1	176.3	-163	60.2	0	0	0	111.3	L386 S392 R393 C394	L386-W390 WeakPolarHBondContact O-CB 3.25Å; L386-W390 PolarHBondContact O-N 3.38Å; W390-S392 VanDerWaalsContact C-N 3.27Å; W390-S392 PolarHBondContact O-N 3.04Å; W390-R393 PolarHBondContact O-N 3.23Å; W390-C394 PolarHBondContact O-N 2.97Å
391	R	88.3	Confident	72.8	Confident	159 Å²	159	110 Å²	110	60%	0.6	57%	0.57	S	S	*	*	H	α-helix	trans	-60	-32.3	171.9	-79.3	-170.9	-74.9	-154.6	2.6	113.9	K387	K387-R391 WeakPolarHBondContact O-CB 3.25Å; K387-R391 WeakPolarHBondContact O-CG 3.34Å; K387-R391 PolarHBondContact O-N 3.06Å
392	S	85.6	Confident	70.2	Confident	78 Å²	78	111.8 Å²	111.8	55%	0.545	58%	0.582	S	S	.	*	H	α-helix	trans	-75.1	-24	174.4	67.5	0	0	0	0	114.3	R388 K389 W390	R388-S392 PolarHBondContact O-N 2.99Å; R388-S392 VanDerWaalsContact O-N 3.14Å; K389-S392 WeakPolarHBondContact CA-OG 3.35Å; K389-S392 PolarHBondContact O-N 3.17Å; K389-S392 PolarHBondContact O-OG 2.91Å; W390-S392 VanDerWaalsContact C-N 3.27Å; W390-S392 PolarHBondContact O-N 3.04Å
393	R	81.8	Confident	67.7	Low	198 Å²	198	123 Å²	123	75%	0.747	63%	0.626	S	S	*	*	H	α-helix	trans	-93.5	-25.9	-179.4	-82.8	-160.5	175.7	165.6	-0.4	113.6	K389 W390 P395	K389-R393 PolarHBondContact O-N 2.83Å; K389-R393 VanDerWaalsContact O-N 3.09Å; W390-R393 PolarHBondContact O-N 3.23Å; R393-P395 WeakPolarHBondContact O-CD 2.97Å
394	C	74.2	Confident	64.8	Low	71 Å²	71	129.3 Å²	129.3	48%	0.48	65%	0.645	S	S	.	*	S	Bend	trans	-103.9	79.6	166.3	-64.7	0	0	0	0	108.3	W390 T396	W390-C394 PolarHBondContact O-N 2.97Å; C394-T396 PolarHBondContact O-N 2.92Å
395	P	55.2	Low	62.3	Low	98 Å²	98	132.3 Å²	132.3	64%	0.636	66%	0.661	S	S	*	*			trans	-59.7	114	161.5	25.9	-28.8	0	0	0	105.9	R393 P397	R393-P395 WeakPolarHBondContact O-CD 2.97Å; P395-P397 WeakPolarHBondContact O-CD 3.33Å
396	T	56.3	Low	59.5	Low	126 Å²	126	137.7 Å²	137.7	77%	0.773	70%	0.7	S	S	*	*			trans	-46.2	117.7	168.8	28.2	0	0	0	0	108.4	C394 S398	C394-T396 PolarHBondContact O-N 2.92Å; T396-S398 PolarHBondContact O-N 2.83Å
397	P	44.5	Very low	56.8	Low	117 Å²	117	137 Å²	137	76%	0.76	72%	0.716	S	S	*	*	S	Bend	trans	-62.6	134.1	170.5	-16.7	30.4	0	0	0	108.1	P395	P395-P397 WeakPolarHBondContact O-CD 3.33Å
398	S	39	Very low	54.2	Low	109 Å²	109	136.4 Å²	136.4	76%	0.762	73%	0.727	S	S	*	*			trans	63.7	84.5	170.9	60.7	0	0	0	0	117.8	T396	T396-S398 PolarHBondContact O-N 2.83Å
399	A	41.2	Very low	51.6	Low	111 Å²	111	136 Å²	136	92%	0.917	74%	0.742	S	S	*	*			trans	-108	61.5	133	0	0	0	0	0	107.7
400	S	35.6	Very low	49.2	Very low	106 Å²	106	140.7 Å²	140.7	74%	0.741	76%	0.763	S	S	*	*			trans	-144.7	64.7	173.9	-162.3	0	0	0	0	107.9
401	R	35.6	Very low	46.7	Very low	219 Å²	219	138.1 Å²	138.1	83%	0.826	77%	0.772	S	S	*	*	S	Bend	trans	-179.8	121.9	159.7	-109.1	167.6	124.7	155.1	-1.8	108.9
402	D	32.7	Very low	44.3	Very low	127 Å²	127	141.4 Å²	141.4	68%	0.679	79%	0.785	S	S	*	*			trans	67.1	72.4	151.3	-50.6	-33	0	0	0	118.8
403	Y	36.2	Very low	42.1	Very low	241 Å²	241	145.7 Å²	145.7	95%	0.945	80%	0.802	S	S	*	*			trans	-116	66.3	139.4	-83.3	-81.7	0	0	0	109.1
404	R	31.6	Very low	40	Very low	230 Å²	230	140.1 Å²	140.1	87%	0.868	81%	0.805	S	S	*	*			trans	-132	80.2	161.9	-150.9	-166.5	-62.1	-154	2.8	105.6
405	V	36	Very low	38.3	Very low	145 Å²	145	141.8 Å²	141.8	88%	0.879	82%	0.818	S	S	*	*			trans	171.6	95.9	162.1	164	0	0	0	0	106.5
406	C	31.5	Very low	37.6	Very low	138 Å²	138	146.4 Å²	146.4	93%	0.932	83%	0.831	S	S	*	*	S	Bend	trans	172	106.7	134.7	-154.6	0	0	0	0	107.2
407	G	33.3	Very low	36.8	Very low	80 Å²	80	143.9 Å²	143.9	83%	0.825	83%	0.83	S	S	*	*			trans	144.8	47.3	179.9	0	0	0	0	0	114.7
408	S	34.9	Very low	36.6	Very low	110 Å²	110	142.8 Å²	142.8	77%	0.769	83%	0.831	S	S	*	*			trans	-150.5	147.3	156.6	62.8	0	0	0	0	108.7
409	S	34.8	Very low	36.4	Very low	110 Å²	110	144.8 Å²	144.8	77%	0.769	83%	0.832	S	S	*	*			trans	97.3	81.4	179.3	-35.9	0	0	0	0	115.5
410	F	36.2	Very low	36.2	Very low	202 Å²	202	147.5 Å²	147.5	89%	0.886	83%	0.826	S	S	*	*				-163	96.5	122.4	-124.3	-92	0	0	0	109.5
411	S	35.9	Very low	36.2	Very low	125 Å²	125	152.3 Å²	152.3	87%	0.874	83%	0.834	S	S	*	*			trans	-105.6	121	163	-64.2	0	0	0	0	107.6
412	R	39	Very low	36.1	Very low	228 Å²	228	150.7 Å²	150.7	86%	0.86	84%	0.835	S	S	*	*			trans	-154.4	116.8	154.7	-146.8	168.4	86	159.6	3.7	111.3
413	N	38.3	Very low	36.4	Very low	169 Å²	169	156.1 Å²	156.1	90%	0.904	85%	0.846	S	S	*	*			trans	-6	139.7	161.4	-70.8	-8.9	0	0	0	119.3
414	G	37.3	Very low	36.3	Very low	80 Å²	80	147.8 Å²	147.8	83%	0.825	83%	0.834	S	S	*	*			trans	173.7	115.7	157.1	0	0	0	0	0	112.3
415	S	39.8	Very low	36.6	Very low	106 Å²	106	142.6 Å²	142.6	74%	0.741	83%	0.833	S	S	*	*			trans	-69.2	161.7	-172.5	-60.3	0	0	0	0	116.7
416	E	40.4	Very low	36.6	Very low	195 Å²	195	147.2 Å²	147.2	91%	0.911	84%	0.835	S	S	*	*			trans	74.5	135.6	140.8	-78	167.6	142	0	0	122.3
417	G	38.4	Very low	37	Very low	74 Å²	74	145.8 Å²	145.8	76%	0.763	83%	0.832	S	S	*	*			trans	112.5	90.4	159.2	0	0	0	0	0	114.3
418	A	40.1	Very low	37.2	Very low	93 Å²	93	150.6 Å²	150.6	77%	0.769	83%	0.833	S	S	*	*				92	122.6	81.1	0	0	0	0	0	114.9
419	L	36.4	Very low	37.2	Very low	151 Å²	151	150 Å²	150	79%	0.791	83%	0.829	S	S	*	*			trans	79.9	104.8	148.7	-85.1	127.6	0	0	0	122.6
420	Q	36.7	Very low	37.3	Very low	168 Å²	168	153.5 Å²	153.5	79%	0.785	83%	0.831	S	S	*	*				29.4	126.4	128.1	-73.9	175	-32.8	0	0	120.5
421	F	35.1	Very low	37.3	Very low	207 Å²	207	151.3 Å²	151.3	91%	0.908	83%	0.828	S	S	*	*				-158	131.3	126.8	-124.1	-86.8	0	0	0	112.2
422	H	33.7	Very low	37.4	Very low	185 Å²	185	154 Å²	154	86%	0.856	83%	0.826	S	S	*	*			trans	-113.1	124.5	-177	-138.9	-73.3	0	0	0	109
423	R	38.6	Very low	37.2	Very low	241 Å²	241	148.9 Å²	148.9	91%	0.909	82%	0.821	S	S	*	*			trans	-177.4	124.6	163.6	-129.4	174.8	-179	159.1	0.6	106.2
424	G	34.2	Very low	37.1	Very low	67 Å²	67	149.2 Å²	149.2	69%	0.691	82%	0.817	S	S	*	*			cis	121.2	92	22.2	0	0	0	0	0	108.8
425	S	38	Very low	37.2	Very low	120 Å²	120	152.6 Å²	152.6	84%	0.839	82%	0.821	S	S	*	*			trans	162.7	115.8	145.2	-84.7	0	0	0	0	115.2
426	R	36.4	Very low	36.8	Very low	243 Å²	243	152.5 Å²	152.5	92%	0.917	82%	0.821	S	S	*	*				61.1	108.3	115.9	-138.1	176.5	-166.2	161.2	2	119.9
427	A	39.6	Very low	36.6	Very low	107 Å²	107	149.6 Å²	149.6	88%	0.884	82%	0.816	S	S	*	*				149.8	135.9	115.9	0	0	0	0	0	112.9
428	Q	38.1	Very low	36.4	Very low	181 Å²	181	157.5 Å²	157.5	85%	0.846	84%	0.839	S	S	*	*			trans	-125	145.7	-170.7	-140.9	179.2	-0.9	0	0	109.7
429	S	34.4	Very low	36.2	Very low	98 Å²	98	160.8 Å²	160.8	69%	0.685	84%	0.842	S	S	*	*			trans	82.3	162.3	144.6	78.3	0	0	0	0	122.2
430	F	36.2	Very low	36.2	Very low	184 Å²	184	161.3 Å²	161.3	81%	0.807	85%	0.845	S	S	*	*			trans	99	125.1	174.2	-71.3	-83	0	0	0	115.6
431	L	37	Very low	36.2	Very low	156 Å²	156	160.9 Å²	160.9	82%	0.817	85%	0.848	S	S	*	*			cis	-159.5	118.3	25.8	-145.3	131.4	0	0	0	109.9
432	Q	36.7	Very low	36.3	Very low	180 Å²	180	158.2 Å²	158.2	84%	0.841	85%	0.845	S	S	*	*			trans	-111.1	127.4	167.4	-178.8	171.4	-16.5	0	0	106.8
433	T	34.8	Very low	36.4	Very low	121 Å²	121	156.5 Å²	156.5	74%	0.742	84%	0.844	S	S	*	*			trans	34.6	107.1	148.6	-38.3	0	0	0	0	118.3
434	E	36.8	Very low	36.3	Very low	177 Å²	177	150.9 Å²	150.9	83%	0.827	84%	0.84	S	S	*	*			trans	-171.1	132.1	139.5	-111.2	177.5	178.9	0	0	111.1
435	T	39.2	Very low	36.4	Very low	150 Å²	150	156.9 Å²	156.9	92%	0.92	85%	0.85	S	S	*	*			trans	-178.2	84.7	138.9	23.3	0	0	0	0	108.6
436	S	31.6	Very low	36.3	Very low	105 Å²	105	159.7 Å²	159.7	73%	0.734	85%	0.851	S	S	*	*			trans	-104	150.6	142.7	51.2	0	0	0	0	107.1
437	V	37.2	Very low	36.3	Very low	134 Å²	134	152.8 Å²	152.8	81%	0.812	85%	0.846	S	S	*	*			trans	85.4	89.6	178	-159	0	0	0	0	113
438	I	34.3	Very low	36	Very low	240 Å²	240	156.9 Å²	156.9	100%	1.231	84%	0.842	S	S	*	*				-157.5	0	86.8	-79	166.3	0	0	0	107.4

Retrieved 438 of 438 residues in 85.5 ms (Link to these results)

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