HEN2_HUMAN Loading...

Helix-loop-helix protein 2

Transcription factor which binds the E box motif 5'-CA[TC][AG]TG-3'. Involved in regulating energy expenditure, body mass, voluntary physical activity, mating behavior and reproductive longevity, acting through the hypothalamic-pituitary-gonadal axis. Acts as a transcriptional activator of target genes, including NDN, PCSK1, MC4R (By similarity). Is also a transcriptional activator of KISS1¹. May act centrally to regulate function of both white and brown adipose tissue. Together with NHLH1, required to maintain migration and survival of cells in the anterior extramural migration stream (aes), which forms the precerebellar nuclei. Also, in concert with NHLH1, may determine fate of gonadotropin releasing hormone-1 (GnRH-1) neurons.

AlphaFold DB , UniProt , Accession Q02577, Species HUMAN (Homo sapiens, Human), Gene NHLH2, Length 135 aa.

						>HEN2_HUMAN|Q02577|NHLH2
MMLSPDQAADSDHPSSAHSDPESLGGTDTKVLGSVSDLEPVEEAEGDGKGGSRAALYPHPQQLSREEKRRRRRATAKYRSAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV
					

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	60	Low	62.5	Low	246 Å²	246	147.9 Å²	147.9	100%	1.212	86%	0.859	S	S	*	*				0	112.2	0	-69.3	179.5	-175.8	0	0	107.1
2	M	51.2	Low	61.8	Low	188 Å²	188	149.3 Å²	149.3	93%	0.926	86%	0.861	S	S	*	*			trans	-84.9	138.5	176.5	-71.7	-148.9	170.4	0	0	109.7
3	L	74.9	Confident	61.7	Low	175 Å²	175	151.1 Å²	151.1	92%	0.916	86%	0.856	S	S	*	*			trans	-132.3	109.9	164.5	-83.3	159.4	0	0	0	108
4	S	70.4	Confident	61.3	Low	112 Å²	112	148.6 Å²	148.6	78%	0.783	85%	0.849	S	S	*	*			trans	-72.6	151.6	172.5	-57	0	0	0	0	111.5
5	P	66.8	Low	61.2	Low	128 Å²	128	146.3 Å²	146.3	83%	0.831	85%	0.846	S	S	*	*			trans	-108.9	125.5	162	33.4	-21	0	0	0	111
6	D	63.6	Low	60.3	Low	143 Å²	143	143.9 Å²	143.9	77%	0.765	84%	0.84	S	S	*	*			trans	-150.4	119.8	163.2	-172.4	38.5	0	0	0	109.4
7	Q	63.8	Low	59.9	Low	183 Å²	183	140.5 Å²	140.5	86%	0.855	83%	0.832	S	S	*	*				176.9	131.4	123.4	-100.9	175.8	-1.1	0	0	112.3
8	A	52.1	Low	59.5	Low	98 Å²	98	142.9 Å²	142.9	81%	0.81	83%	0.833	S	S	*	*			trans	-90.3	154	176.3	0	0	0	0	0	112.5
9	A	63.7	Low	59.1	Low	96 Å²	96	139.9 Å²	139.9	79%	0.793	82%	0.821	S	S	*	*			trans	-177	105.2	151.1	0	0	0	0	0	106.6
10	D	56.3	Low	58.9	Low	151 Å²	151	140.7 Å²	140.7	81%	0.807	82%	0.822	S	S	*	*				65.6	128.6	81.8	-166.5	56.6	0	0	0	115
11	S	64.3	Low	58.7	Low	107 Å²	107	139.6 Å²	139.6	75%	0.748	82%	0.819	S	S	*	*			trans	144.9	95.4	141.3	-70.4	0	0	0	0	112.2
12	D	54	Low	58.2	Low	165 Å²	165	137.4 Å²	137.4	88%	0.882	81%	0.806	S	S	*	*			trans	-74.6	143.3	161.5	-88.3	-52	0	0	0	111
13	H	60.9	Low	58.2	Low	172 Å²	172	132.9 Å²	132.9	80%	0.796	79%	0.793	S	S	*	*			trans	-153.2	121	159.2	-153.4	-45.4	0	0	0	110.5
14	P	55.5	Low	57.3	Low	117 Å²	117	132.8 Å²	132.8	76%	0.76	79%	0.792	S	S	*	*			trans	-108.4	125.2	155.3	31.3	-21.1	0	0	0	109.4
15	S	60.4	Low	55.9	Low	114 Å²	114	131.3 Å²	131.3	80%	0.797	79%	0.794	S	S	*	*			trans	-91.9	135.8	175.8	-177.8	0	0	0	0	110.4
16	S	46.9	Very low	54.6	Low	108 Å²	108	129 Å²	129	76%	0.755	79%	0.794	S	S	*	*			trans	-112.7	131.1	177.4	53.8	0	0	0	0	111.1
17	A	54	Low	54.2	Low	86 Å²	86	128.5 Å²	128.5	71%	0.711	80%	0.796	S	S	*	*			trans	-173.4	120.4	153.6	0	0	0	0	0	108.4
18	H	51.6	Low	53.5	Low	183 Å²	183	126.5 Å²	126.5	85%	0.847	79%	0.791	S	S	*	*				54	130.1	84.1	-67	-68.6	0	0	0	112.5
19	S	52	Low	53.6	Low	86 Å²	86	128.5 Å²	128.5	60%	0.601	79%	0.794	S	S	*	*			cis	-159.2	158.1	2.9	-63.2	0	0	0	0	105.1
20	D	54.9	Low	53.1	Low	156 Å²	156	132.4 Å²	132.4	83%	0.834	79%	0.793	S	S	*	*				171.1	150.5	89.8	-75.7	-42.2	0	0	0	108.8
21	P	54.6	Low	52.6	Low	118 Å²	118	131.6 Å²	131.6	77%	0.766	79%	0.793	S	S	*	*			trans	-121.4	119.6	173.6	35.5	-20.3	0	0	0	113.7
22	E	51.2	Low	52	Low	199 Å²	199	134.9 Å²	134.9	93%	0.93	80%	0.801	S	S	*	*			trans	-163.4	154.7	160	-68.6	-154.3	110	0	0	107.7
23	S	50.9	Low	51.4	Low	94 Å²	94	129.9 Å²	129.9	66%	0.657	79%	0.789	S	S	*	*			cis	-174.9	151.7	-26.4	-174.1	0	0	0	0	104.6
24	L	54.5	Low	50.7	Low	173 Å²	173	126.9 Å²	126.9	91%	0.906	79%	0.787	S	S	*	*			trans	79.7	118.1	163.5	-46.5	177.4	0	0	0	119.4
25	G	41.9	Very low	50.7	Low	80 Å²	80	127.9 Å²	127.9	83%	0.825	79%	0.791	S	S	*	*			trans	160.4	67.7	161.4	0	0	0	0	0	114
26	G	40.3	Very low	50.1	Low	80 Å²	80	126.7 Å²	126.7	83%	0.825	78%	0.782	S	S	*	*			trans	-76.5	123.4	176.4	0	0	0	0	0	112.9
27	T	54.6	Low	49.7	Very low	133 Å²	133	128.5 Å²	128.5	82%	0.816	78%	0.783	S	S	*	*			trans	-145.6	122.4	147.5	51.7	0	0	0	0	108.9	T29	T27-T29 PolarHBondContact O-N 3.32Å
28	D	49.8	Very low	49.7	Very low	140 Å²	140	132.4 Å²	132.4	75%	0.749	79%	0.792	S	S	*	*			trans	-51.1	115.7	-178.7	-68.1	-94.3	0	0	0	114.8
29	T	52.6	Low	49.2	Very low	140 Å²	140	131.2 Å²	131.2	86%	0.859	79%	0.787	S	S	*	*			trans	-130.9	92.9	142.9	47.9	0	0	0	0	108.1	T27	T27-T29 PolarHBondContact O-N 3.32Å
30	K	53.6	Low	48.9	Very low	178 Å²	178	131 Å²	131	77%	0.774	78%	0.783	S	S	*	*			trans	-70.3	139.5	173.8	-68.5	-173.8	174.8	-172.5	0	109.9
31	V	46.7	Very low	48.8	Very low	135 Å²	135	129.9 Å²	129.9	82%	0.818	78%	0.781	S	S	*	*			trans	80.5	69.6	159.7	-159	0	0	0	0	116.4
32	L	51.6	Low	48.1	Very low	176 Å²	176	132.5 Å²	132.5	92%	0.921	78%	0.783	S	S	*	*			trans	-104.1	106.5	140.3	-97	155.4	0	0	0	106.8	S34	L32-S34 PolarHBondContact O-N 2.88Å; L32-S34 VanDerWaalsContact O-N 3.11Å
33	G	41.2	Very low	47.6	Very low	60 Å²	60	132 Å²	132	62%	0.619	78%	0.781	S	S	*	*			trans	-52.2	114.9	-172.9	0	0	0	0	0	111.8	V35	G33-V35 VanDerWaalsContact C-N 3.3Å; G33-V35 PolarHBondContact O-N 3.01Å
34	S	44.9	Very low	47.2	Very low	108 Å²	108	131.3 Å²	131.3	76%	0.755	78%	0.781	S	S	*	*			trans	-53.6	99.8	152.5	-170.1	0	0	0	0	106.6	L32 S36	L32-S34 PolarHBondContact O-N 2.88Å; L32-S34 VanDerWaalsContact O-N 3.11Å; S34-S36 PolarHBondContact O-N 2.96Å
35	V	57.6	Low	46.5	Very low	138 Å²	138	131.6 Å²	131.6	84%	0.836	78%	0.778	S	S	*	*			trans	-73.7	82	165.9	-76.7	0	0	0	0	105.9	G33 D37	G33-V35 VanDerWaalsContact C-N 3.3Å; G33-V35 PolarHBondContact O-N 3.01Å; V35-D37 PolarHBondContact O-N 3.45Å
36	S	46.9	Very low	46.4	Very low	89 Å²	89	131.3 Å²	131.3	62%	0.622	78%	0.775	S	S	*	*			trans	-44.1	127.5	161	-58.7	0	0	0	0	108	S34 L38	S34-S36 PolarHBondContact O-N 2.96Å; S36-L38 PolarHBondContact O-N 2.92Å
37	D	39.1	Very low	46.2	Very low	146 Å²	146	133.7 Å²	133.7	78%	0.781	77%	0.769	S	S	*	*			trans	-38.7	101.7	173.2	-73.5	-67.8	0	0	0	111	V35 E39	V35-D37 PolarHBondContact O-N 3.45Å; D37-E39 VanDerWaalsContact C-N 3.35Å; D37-E39 PolarHBondContact O-N 2.91Å
38	L	53.7	Low	45.7	Very low	168 Å²	168	131.1 Å²	131.1	88%	0.88	77%	0.768	S	S	*	*			trans	-87.1	90.9	160.3	-73	174.4	0	0	0	106	S36 P40	S36-L38 PolarHBondContact O-N 2.92Å; L38-P40 WeakPolarHBondContact O-CD 3.38Å
39	E	41.1	Very low	45.2	Very low	159 Å²	159	133.2 Å²	133.2	74%	0.743	77%	0.771	S	S	*	*			trans	-34.2	113.4	164.8	-66.5	-74.1	108.6	0	0	110.8	D37 V41	D37-E39 VanDerWaalsContact C-N 3.35Å; D37-E39 PolarHBondContact O-N 2.91Å; E39-V41 PolarHBondContact O-N 3.41Å
40	P	44.8	Very low	44.5	Very low	81 Å²	81	130.4 Å²	130.4	53%	0.526	77%	0.769	S	S	.	*			trans	-76.7	112.2	161.6	3	15.1	0	0	0	106.9	L38 E42 K77	L38-P40 WeakPolarHBondContact O-CD 3.38Å; P40-E42 PolarHBondContact O-N 2.97Å; P40-K77 HydrophobicContact CG-CD 4.17Å
41	V	53	Low	43.8	Very low	132 Å²	132	125.2 Å²	125.2	80%	0.8	77%	0.766	S	S	*	*			trans	-27.3	126.4	166.3	176.3	0	0	0	0	111.3	E39 E43	E39-V41 PolarHBondContact O-N 3.41Å; V41-E43 PolarHBondContact O-N 3.21Å
42	E	40.8	Very low	43.9	Very low	173 Å²	173	125 Å²	125	81%	0.808	77%	0.77	S	S	*	*			trans	-52	109.1	175.1	-59.5	-154	139.1	0	0	110.2	P40 A44	P40-E42 PolarHBondContact O-N 2.97Å; E42-A44 PolarHBondContact O-N 3.19Å
43	E	40.7	Very low	44	Very low	189 Å²	189	127.1 Å²	127.1	88%	0.883	77%	0.766	S	S	*	*			trans	-72.7	76.7	153.8	-71.9	-178.3	179.7	0	0	106.5	V41 E45	V41-E43 PolarHBondContact O-N 3.21Å; E43-E45 PolarHBondContact O-N 2.89Å
44	A	41.2	Very low	44.6	Very low	80 Å²	80	129 Å²	129	66%	0.661	78%	0.776	S	S	*	*			trans	-64	92.1	160.5	0	0	0	0	0	107	E42 G46	E42-A44 PolarHBondContact O-N 3.19Å; A44-G46 PolarHBondContact O-N 3.33Å
45	E	39.8	Very low	45	Very low	179 Å²	179	127.8 Å²	127.8	84%	0.836	77%	0.772	S	S	*	*			trans	-56.6	120.6	161.8	-76.8	-164.3	144.5	0	0	107.6	E43 D47	E43-E45 PolarHBondContact O-N 2.89Å; E45-D47 PolarHBondContact O-N 3.32Å
46	G	40.1	Very low	44.7	Very low	73 Å²	73	129.1 Å²	129.1	75%	0.753	77%	0.774	S	S	*	*			trans	-54.2	131.1	-166.6	0	0	0	0	0	114.2	A44 G48	A44-G46 PolarHBondContact O-N 3.33Å; G46-G48 VanDerWaalsContact C-N 3.34Å; G46-G48 PolarHBondContact O-N 3.26Å
47	D	36.7	Very low	44.7	Very low	131 Å²	131	133.6 Å²	133.6	70%	0.701	78%	0.779	S	S	*	*			trans	-61.8	89.7	163.3	-174.1	46.8	0	0	0	109.5	E45 K49	E45-D47 PolarHBondContact O-N 3.32Å; D47-K49 VanDerWaalsContact C-N 3.29Å; D47-K49 PolarHBondContact O-N 3.01Å
48	G	43.1	Very low	45.7	Very low	78 Å²	78	132.3 Å²	132.3	80%	0.804	78%	0.779	S	S	*	*			trans	-74.5	76.7	171.4	0	0	0	0	0	111.6	G46 G50	G46-G48 VanDerWaalsContact C-N 3.34Å; G46-G48 PolarHBondContact O-N 3.26Å; G48-G50 PolarHBondContact O-N 3.03Å
49	K	41.1	Very low	45.7	Very low	185 Å²	185	132.4 Å²	132.4	80%	0.804	77%	0.774	S	S	*	*			trans	-69.3	110.6	165.5	-98.4	169.2	171.3	159	0	110.3	D47	D47-K49 VanDerWaalsContact C-N 3.29Å; D47-K49 PolarHBondContact O-N 3.01Å
50	G	37	Very low	46.8	Very low	80 Å²	80	130.5 Å²	130.5	83%	0.825	78%	0.775	S	S	*	*			trans	147.8	106.9	158.2	0	0	0	0	0	115.1	G48	G48-G50 PolarHBondContact O-N 3.03Å
51	G	39.8	Very low	47.8	Very low	69 Å²	69	135.2 Å²	135.2	71%	0.711	79%	0.79	S	S	*	*			trans	145.6	86.8	161.2	0	0	0	0	0	114.8	R53	G51-R53 PolarHBondContact O-N 2.8Å
52	S	48.5	Very low	49.1	Very low	130 Å²	130	137.7 Å²	137.7	91%	0.909	79%	0.793	S	S	*	*			trans	-54.4	91.8	171.5	-55.1	0	0	0	0	113
53	R	53.8	Low	50.9	Low	221 Å²	221	133 Å²	133	83%	0.834	77%	0.773	S	S	*	*			trans	-144.8	72.7	161.9	-64.5	-174.2	82.6	147.7	0.9	109.9	G51 A55	G51-R53 PolarHBondContact O-N 2.8Å; R53-A55 PolarHBondContact O-N 2.89Å
54	A	52.6	Low	53.1	Low	99 Å²	99	127.7 Å²	127.7	82%	0.818	76%	0.757	S	S	*	*			trans	-73.4	31.4	-175.4	0	0	0	0	0	115.4
55	A	54.2	Low	55.5	Low	83 Å²	83	132.7 Å²	132.7	69%	0.686	76%	0.759	S	S	*	*	S	Bend	trans	-143.1	71.1	-173.9	0	0	0	0	0	111.6	R53	R53-A55 PolarHBondContact O-N 2.89Å
56	L	51.9	Low	58	Low	166 Å²	166	128 Å²	128	87%	0.869	74%	0.737	S	S	*	*			trans	169.6	68.3	152.9	-115	73.2	0	0	0	109.1
57	Y	45.8	Very low	60.5	Low	183 Å²	183	128.2 Å²	128.2	72%	0.718	72%	0.718	S	S	*	*			trans	-108	109	173.1	-69.4	-73.9	0	0	0	109.4	H59	Y57-H59 PolarHBondContact O-N 2.95Å
58	P	60.7	Low	63.1	Low	120 Å²	120	127.5 Å²	127.5	78%	0.779	71%	0.709	S	S	*	*			trans	-59.9	125.9	164.9	16.7	-14	0	0	0	107
59	H	54.2	Low	65.6	Low	169 Å²	169	129.2 Å²	129.2	78%	0.782	69%	0.691	S	S	*	*			trans	-47.3	135.9	173.7	-86.4	-12.4	0	0	0	109.7	Y57 Q61	Y57-H59 PolarHBondContact O-N 2.95Å; H59-Q61 PolarHBondContact O-N 3.26Å
60	P	63.2	Low	68.1	Low	119 Å²	119	126.9 Å²	126.9	77%	0.773	68%	0.677	S	S	*	*			trans	-59.3	103.9	174	24	-31.2	0	0	0	107.7	Q62	P60-Q62 PolarHBondContact O-N 3Å
61	Q	66.1	Low	70.8	Confident	180 Å²	180	131.1 Å²	131.1	84%	0.841	67%	0.668	S	S	*	*			trans	-57.7	115.4	174.8	-73.4	-178.6	-29.8	0	0	106.8	H59 L63	H59-Q61 PolarHBondContact O-N 3.26Å; Q61-L63 PolarHBondContact O-N 2.86Å
62	Q	79.4	Confident	73.4	Confident	185 Å²	185	136.8 Å²	136.8	86%	0.864	67%	0.668	S	S	*	*			trans	-58.9	115.6	179.6	-68.6	-165.6	-2.6	0	0	108.5	P60 S64	P60-Q62 PolarHBondContact O-N 3Å; Q62-S64 PolarHBondContact O-N 2.87Å
63	L	78.4	Confident	75.7	Confident	73 Å²	73	137.4 Å²	137.4	38%	0.382	65%	0.651	S	S	.	*			trans	-58.7	129	176.4	-62.7	-177.7	0	0	0	109	Q61 E67 K68	Q61-L63 PolarHBondContact O-N 2.86Å; L63-E67 HydrophobicContact CB-CB 4.11Å; L63-E67 HydrophobicContact CB-CG 4.27Å; L63-E67 HydrophobicContact CD1-CG 4.33Å; L63-E67 HydrophobicContact CD2-CG 3.86Å; L63-E67 HydrophobicContact CG-CG 4.37Å; L63-K68 HydrophobicContact CB-CG 3.87Å; L63-K68 WeakPolarHBondContact O-CE 3.47Å
64	S	88.7	Confident	77.6	Confident	78 Å²	78	130 Å²	130	55%	0.545	64%	0.637	S	S	.	*			trans	-48.8	149.3	169.2	170.4	0	0	0	0	110.1	Q62 E66 E67 K68	Q62-S64 PolarHBondContact O-N 2.87Å; S64-E66 PolarHBondContact O-N 3.41Å; S64-E66 PolarHBondContact OG-N 3.11Å; S64-E67 PolarHBondContact O-N 3.29Å; S64-K68 PolarHBondContact O-N 3.11Å
65	R	90	Very high	79.7	Confident	185 Å²	185	128.3 Å²	128.3	70%	0.698	62%	0.617	S	S	*	*	H	α-helix	trans	-49.2	-35.6	173.9	-176.1	-178.5	-177.6	-168.1	3.1	111.6	R69	R65-R69 WeakPolarHBondContact O-CG 3.3Å; R65-R69 PolarHBondContact O-N 3.46Å
66	E	92.9	Very high	81.8	Confident	80 Å²	80	127.2 Å²	127.2	37%	0.374	61%	0.607	S	S	.	*	H	α-helix	trans	-67.4	-43.9	176.9	-178.7	52.3	-151.5	0	0	112.1	S64 K68 R69 R70	S64-E66 PolarHBondContact O-N 3.41Å; S64-E66 PolarHBondContact OG-N 3.11Å; E66-K68 PolarHBondContact O-N 2.99Å; E66-R69 WeakPolarHBondContact O-CB 3.34Å; E66-R69 PolarHBondContact O-N 3.21Å; E66-R69 VanDerWaalsContact O-N 3.13Å; E66-R70 WeakPolarHBondContact O-CG 3.17Å; E66-R70 PolarHBondContact O-N 3.21Å; E66-R70 IonicContact OE1-CZ 3.81Å; E66-R70 IonicContact OE1-NE 3.89Å; E66-R70 PolarHBondContact OE1-NE 2.68Å; E66-R70 VanDerWaalsContact OE1-NE 3.09Å; E66-R70 IonicContact OE1-NH2 3.09Å
67	E	92.8	Very high	83.9	Confident	79 Å²	79	126.3 Å²	126.3	37%	0.369	60%	0.596	S	S	.	*	H	α-helix	trans	-67.6	-38.4	179.9	-168.1	53	-132.7	0	0	111.8	L63 S64 R69 R70 R71	L63-E67 HydrophobicContact CB-CB 4.11Å; L63-E67 HydrophobicContact CB-CG 4.27Å; L63-E67 HydrophobicContact CD1-CG 4.33Å; L63-E67 HydrophobicContact CD2-CG 3.86Å; L63-E67 HydrophobicContact CG-CG 4.37Å; S64-E67 PolarHBondContact O-N 3.29Å; E67-R69 VanDerWaalsContact C-N 3.3Å; E67-R69 PolarHBondContact O-N 2.64Å; E67-R70 PolarHBondContact O-N 3.28Å; E67-R70 IonicContact OE2-NH1 3.04Å; E67-R71 PolarHBondContact O-N 3.26Å
68	K	92.2	Very high	86.4	Confident	115 Å²	115	121.7 Å²	121.7	50%	0.5	58%	0.578	S	S	.	*	H	α-helix	trans	-59.6	-39.6	171.3	-67.3	-179.3	-178.4	174.5	0	112	L63 S64 E66 R72	L63-K68 HydrophobicContact CB-CG 3.87Å; L63-K68 WeakPolarHBondContact O-CE 3.47Å; S64-K68 PolarHBondContact O-N 3.11Å; E66-K68 PolarHBondContact O-N 2.99Å; K68-R72 WeakPolarHBondContact O-CG 3.45Å; K68-R72 PolarHBondContact O-N 3.13Å; K68-R72 VanDerWaalsContact O-N 3.07Å
69	R	94.2	Very high	88.1	Confident	115 Å²	115	122.5 Å²	122.5	43%	0.434	57%	0.566	S	S	.	*	H	α-helix	trans	-66.4	-43.5	176	-76.3	174.1	167.6	-169.2	-4.2	111.5	R65 E66 E67 R72 R73	R65-R69 WeakPolarHBondContact O-CG 3.3Å; R65-R69 PolarHBondContact O-N 3.46Å; E66-R69 WeakPolarHBondContact O-CB 3.34Å; E66-R69 PolarHBondContact O-N 3.21Å; E66-R69 VanDerWaalsContact O-N 3.13Å; E67-R69 VanDerWaalsContact C-N 3.3Å; E67-R69 PolarHBondContact O-N 2.64Å; R69-R72 PolarHBondContact O-N 3.27Å; R69-R73 WeakPolarHBondContact O-CG 3.31Å; R69-R73 PolarHBondContact O-N 3.36Å
70	R	95.2	Very high	90.2	Very high	136 Å²	136	117.8 Å²	117.8	51%	0.513	55%	0.552	S	S	.	*	H	α-helix	trans	-59.7	-49.8	175.6	-69.6	174	-175.8	-172.4	-3.8	111.4	E66 E67 R72 R73 A74	E66-R70 WeakPolarHBondContact O-CG 3.17Å; E66-R70 PolarHBondContact O-N 3.21Å; E66-R70 IonicContact OE1-CZ 3.81Å; E66-R70 IonicContact OE1-NE 3.89Å; E66-R70 PolarHBondContact OE1-NE 2.68Å; E66-R70 VanDerWaalsContact OE1-NE 3.09Å; E66-R70 IonicContact OE1-NH2 3.09Å; E67-R70 PolarHBondContact O-N 3.28Å; E67-R70 IonicContact OE2-NH1 3.04Å; R70-R72 VanDerWaalsContact C-N 3.33Å; R70-R72 PolarHBondContact O-N 2.89Å; R70-R73 PolarHBondContact O-N 3.12Å; R70-R73 VanDerWaalsContact O-N 3.12Å; R70-A74 WeakPolarHBondContact O-CB 3.4Å; R70-A74 PolarHBondContact O-N 2.95Å
71	R	93.4	Very high	91.8	Very high	168 Å²	168	114 Å²	114	63%	0.634	53%	0.531	S	S	*	.	H	α-helix	trans	-57.4	-43.9	176.8	-163.9	176.3	-168.1	-176.1	2.1	111.9	E67 A74 T75	E67-R71 PolarHBondContact O-N 3.26Å; R71-A74 PolarHBondContact O-N 3.36Å; R71-T75 WeakPolarHBondContact O-CG2 3.35Å; R71-T75 PolarHBondContact O-N 3.07Å
72	R	93.8	Very high	93.3	Very high	189 Å²	189	110 Å²	110	71%	0.713	51%	0.512	S	S	*	.	H	α-helix	trans	-61	-46.5	174.7	-77	-175.4	-177.3	-100.9	2.6	112.3	K68 R69 R70 A74 T75 Y78	K68-R72 WeakPolarHBondContact O-CG 3.45Å; K68-R72 PolarHBondContact O-N 3.13Å; K68-R72 VanDerWaalsContact O-N 3.07Å; R69-R72 PolarHBondContact O-N 3.27Å; R70-R72 VanDerWaalsContact C-N 3.33Å; R70-R72 PolarHBondContact O-N 2.89Å; R72-A74 PolarHBondContact O-N 3.36Å; R72-T75 WeakPolarHBondContact O-CB 3.43Å; R72-T75 PolarHBondContact O-N 2.89Å; R72-T75 VanDerWaalsContact O-N 3.13Å; R72-T75 PolarHBondContact O-OG1 2.94Å; R72-Y78 WeakPolarHBondContact O-CB 3.4Å
73	R	95.6	Very high	94.2	Very high	142 Å²	142	103.5 Å²	103.5	54%	0.536	49%	0.49	S	S	.	.	H	α-helix	trans	-64.9	-28.8	178.1	-69.4	179.1	177.2	172.6	-0.4	113	R69 R70 T75 Y78	R69-R73 WeakPolarHBondContact O-CG 3.31Å; R69-R73 PolarHBondContact O-N 3.36Å; R70-R73 PolarHBondContact O-N 3.12Å; R70-R73 VanDerWaalsContact O-N 3.12Å; R73-T75 VanDerWaalsContact C-N 3.31Å; R73-Y78 HydrophobicContact CB-CD1 4.03Å; R73-Y78 HydrophobicContact CB-CE1 3.99Å; R73-Y78 HydrophobicContact CG-CD1 4.12Å; R73-Y78 HydrophobicContact CG-CE1 3.67Å; R73-Y78 HydrophobicContact CG-CE2 4.22Å
74	A	95.3	Very high	95.1	Very high	66 Å²	66	103.1 Å²	103.1	55%	0.545	49%	0.491	S	S	.	.	T	Hydrogen-bonded Turn	trans	-80.2	-4.2	175.5	0	0	0	0	0	114	R70 R71 R72 R79	R70-A74 WeakPolarHBondContact O-CB 3.4Å; R70-A74 PolarHBondContact O-N 2.95Å; R71-A74 PolarHBondContact O-N 3.36Å; R72-A74 PolarHBondContact O-N 3.36Å; A74-R79 VanDerWaalsContact C-NH1 3.29Å; A74-R79 PolarHBondContact O-NH1 2.91Å
75	T	96.8	Very high	95.6	Very high	64 Å²	64	105.7 Å²	105.7	39%	0.393	49%	0.489	S	S	.	.	S	Bend	trans	-71.1	144.9	171.7	63.7	0	0	0	0	111.1	R71 R72 R73 K77 Y78 R79	R71-T75 WeakPolarHBondContact O-CG2 3.35Å; R71-T75 PolarHBondContact O-N 3.07Å; R72-T75 WeakPolarHBondContact O-CB 3.43Å; R72-T75 PolarHBondContact O-N 2.89Å; R72-T75 VanDerWaalsContact O-N 3.13Å; R72-T75 PolarHBondContact O-OG1 2.94Å; R73-T75 VanDerWaalsContact C-N 3.31Å; T75-K77 VanDerWaalsContact C-N 3.29Å; T75-K77 PolarHBondContact O-N 3.21Å; T75-Y78 PolarHBondContact O-N 3.13Å; T75-Y78 VanDerWaalsContact OG1-CB 3.3Å; T75-Y78 WeakPolarHBondContact OG1-CB 3.39Å; T75-Y78 PolarHBondContact OG1-N 3.02Å; T75-R79 PolarHBondContact O-N 3.47Å
76	A	97.3	Very high	96	Very high	59 Å²	59	100.5 Å²	100.5	49%	0.488	47%	0.472	S	S	.	.	H	α-helix	trans	-56.8	-45.2	173.6	0	0	0	0	0	110.9	Y78 R79 S80	A76-Y78 VanDerWaalsContact C-N 3.34Å; A76-Y78 PolarHBondContact O-N 3.23Å; A76-R79 PolarHBondContact O-N 3.36Å; A76-R79 VanDerWaalsContact O-N 3.11Å; A76-S80 PolarHBondContact O-N 3.06Å; A76-S80 PolarHBondContact O-OG 2.85Å
77	K	96.1	Very high	96.3	Very high	147 Å²	147	103.1 Å²	103.1	64%	0.639	48%	0.478	S	S	*	.	H	α-helix	trans	-51.5	-47.6	176.5	-173.3	173.7	-175.8	170.2	0	112.7	P40 T75 A81	P40-K77 HydrophobicContact CG-CD 4.17Å; T75-K77 VanDerWaalsContact C-N 3.29Å; T75-K77 PolarHBondContact O-N 3.21Å; K77-A81 VanDerWaalsContact O-CB 3.31Å; K77-A81 WeakPolarHBondContact O-CB 3.44Å; K77-A81 PolarHBondContact O-N 3.39Å
78	Y	97.6	Very high	96.6	Very high	86 Å²	86	103.9 Å²	103.9	34%	0.337	48%	0.484	S	S	.	.	H	α-helix	trans	-63.9	-45.9	178.6	-176	-86.9	0	0	0	112.1	R72 R73 T75 A76 A81 H82	R72-Y78 WeakPolarHBondContact O-CB 3.4Å; R73-Y78 HydrophobicContact CB-CD1 4.03Å; R73-Y78 HydrophobicContact CB-CE1 3.99Å; R73-Y78 HydrophobicContact CG-CD1 4.12Å; R73-Y78 HydrophobicContact CG-CE1 3.67Å; R73-Y78 HydrophobicContact CG-CE2 4.22Å; T75-Y78 PolarHBondContact O-N 3.13Å; T75-Y78 VanDerWaalsContact OG1-CB 3.3Å; T75-Y78 WeakPolarHBondContact OG1-CB 3.39Å; T75-Y78 PolarHBondContact OG1-N 3.02Å; A76-Y78 VanDerWaalsContact C-N 3.34Å; A76-Y78 PolarHBondContact O-N 3.23Å; Y78-A81 PolarHBondContact O-N 3.42Å; Y78-H82 WeakPolarHBondContact O-CB 3.38Å; Y78-H82 PolarHBondContact O-N 2.95Å
79	R	97.2	Very high	96.9	Very high	138 Å²	138	105 Å²	105	52%	0.521	49%	0.485	S	S	.	.	H	α-helix	trans	-62	-46	178.8	-68.3	-164.7	-61.7	-85.6	-1.9	111.7	A74 T75 A76 H82 A83	A74-R79 VanDerWaalsContact C-NH1 3.29Å; A74-R79 PolarHBondContact O-NH1 2.91Å; T75-R79 PolarHBondContact O-N 3.47Å; A76-R79 PolarHBondContact O-N 3.36Å; A76-R79 VanDerWaalsContact O-N 3.11Å; R79-H82 PolarHBondContact O-N 3.42Å; R79-A83 WeakPolarHBondContact O-CB 3.42Å; R79-A83 PolarHBondContact O-N 3.03Å
80	S	97.9	Very high	97.1	Very high	70 Å²	70	102 Å²	102	49%	0.49	48%	0.48	S	S	.	.	H	α-helix	trans	-61.8	-45.1	178.6	-50	0	0	0	0	111.9	A76 A83 T84	A76-S80 PolarHBondContact O-N 3.06Å; A76-S80 PolarHBondContact O-OG 2.85Å; S80-A83 PolarHBondContact O-N 3.37Å; S80-T84 WeakPolarHBondContact O-CB 3.42Å; S80-T84 PolarHBondContact O-N 3.4Å; S80-T84 PolarHBondContact O-OG1 3.34Å
81	A	97.2	Very high	97.3	Very high	40 Å²	40	100.4 Å²	100.4	33%	0.331	48%	0.478	S	S	.	.	H	α-helix	trans	-64	-41.5	176.7	0	0	0	0	0	111.6	K77 Y78 T84 R85	K77-A81 VanDerWaalsContact O-CB 3.31Å; K77-A81 WeakPolarHBondContact O-CB 3.44Å; K77-A81 PolarHBondContact O-N 3.39Å; Y78-A81 PolarHBondContact O-N 3.42Å; A81-T84 PolarHBondContact O-N 2.85Å; A81-R85 WeakPolarHBondContact O-CG 3.34Å; A81-R85 PolarHBondContact O-N 3.09Å
82	H	97.2	Very high	97.5	Very high	94 Å²	94	95.1 Å²	95.1	44%	0.435	47%	0.47	S	S	.	.	H	α-helix	trans	-64.1	-46.5	175.8	-172.3	-72.3	0	0	0	112.2	Y78 R79 T84 R85 E86	Y78-H82 WeakPolarHBondContact O-CB 3.38Å; Y78-H82 PolarHBondContact O-N 2.95Å; R79-H82 PolarHBondContact O-N 3.42Å; H82-T84 VanDerWaalsContact C-N 3.28Å; H82-T84 PolarHBondContact O-N 2.99Å; H82-R85 PolarHBondContact O-N 2.84Å; H82-E86 PolarHBondContact O-N 3.31Å
83	A	98.3	Very high	97.7	Very high	50 Å²	50	90.3 Å²	90.3	41%	0.413	46%	0.455	S	S	.	.	H	α-helix	trans	-59.9	-39.5	176.7	0	0	0	0	0	111.8	R79 S80 E86 R87	R79-A83 WeakPolarHBondContact O-CB 3.42Å; R79-A83 PolarHBondContact O-N 3.03Å; S80-A83 PolarHBondContact O-N 3.37Å; A83-E86 PolarHBondContact O-N 3.04Å; A83-R87 WeakPolarHBondContact O-CB 3.4Å; A83-R87 PolarHBondContact O-N 2.94Å
84	T	98.4	Very high	97.9	Very high	65 Å²	65	86.7 Å²	86.7	40%	0.399	45%	0.446	S	S	.	.	H	α-helix	trans	-65.5	-45.7	177	-58	0	0	0	0	111.9	S80 A81 H82 E86 R87 I88	S80-T84 WeakPolarHBondContact O-CB 3.42Å; S80-T84 PolarHBondContact O-N 3.4Å; S80-T84 PolarHBondContact O-OG1 3.34Å; A81-T84 PolarHBondContact O-N 2.85Å; H82-T84 VanDerWaalsContact C-N 3.28Å; H82-T84 PolarHBondContact O-N 2.99Å; T84-E86 VanDerWaalsContact C-N 3.3Å; T84-E86 PolarHBondContact O-N 3.29Å; T84-R87 WeakPolarHBondContact O-CB 3.49Å; T84-R87 PolarHBondContact O-N 3.24Å; T84-I88 HydrophobicContact CG2-CD1 4.22Å; T84-I88 WeakPolarHBondContact O-CG1 3.37Å; T84-I88 PolarHBondContact O-N 2.92Å
85	R	98.6	Very high	98	Very high	132 Å²	132	89 Å²	89	50%	0.498	45%	0.449	S	S	.	.	H	α-helix	trans	-58.4	-43.5	174.6	-72.9	-170.2	-59.5	-90.6	1.6	112.2	A81 H82 R87 I88 R89	A81-R85 WeakPolarHBondContact O-CG 3.34Å; A81-R85 PolarHBondContact O-N 3.09Å; H82-R85 PolarHBondContact O-N 2.84Å; R85-R87 VanDerWaalsContact C-N 3.35Å; R85-I88 PolarHBondContact O-N 2.94Å; R85-R89 PolarHBondContact O-N 2.97Å
86	E	98.6	Very high	98.1	Very high	75 Å²	75	88.8 Å²	88.8	35%	0.35	45%	0.453	S	S	.	.	H	α-helix	trans	-66.6	-37.6	179.3	-177.4	55.1	-159.2	0	0	112	H82 A83 T84 R89 V90	H82-E86 PolarHBondContact O-N 3.31Å; A83-E86 PolarHBondContact O-N 3.04Å; T84-E86 VanDerWaalsContact C-N 3.3Å; T84-E86 PolarHBondContact O-N 3.29Å; E86-R89 VanDerWaalsContact CD-NE 3.3Å; E86-R89 WeakPolarHBondContact O-CB 3.38Å; E86-R89 PolarHBondContact O-N 2.84Å; E86-R89 IonicContact OE1-CZ 3.88Å; E86-R89 VanDerWaalsContact OE1-CZ 3.24Å; E86-R89 IonicContact OE1-NE 2.67Å; E86-R89 PolarHBondContact OE1-NE 2.67Å; E86-R89 VanDerWaalsContact OE1-NE 3.07Å; E86-R89 IonicContact OE1-NH2 2.84Å; E86-R89 PolarHBondContact OE1-NH2 3.04Å; E86-R89 IonicContact OE2-CZ 3.24Å; E86-R89 IonicContact OE2-NE 3.07Å; E86-R89 PolarHBondContact OE2-NE 3.13Å; E86-R89 IonicContact OE2-NH2 2.63Å; E86-V90 WeakPolarHBondContact O-CG2 3.48Å; E86-V90 PolarHBondContact O-N 3.37Å
87	R	98.6	Very high	98.2	Very high	135 Å²	135	87.5 Å²	87.5	51%	0.509	44%	0.437	S	S	.	.	H	α-helix	trans	-59.4	-49.3	172.7	-171.7	-174.3	-63.1	105.3	0.6	111.5	A83 T84 R85 R89 V90 E91	A83-R87 WeakPolarHBondContact O-CB 3.4Å; A83-R87 PolarHBondContact O-N 2.94Å; T84-R87 WeakPolarHBondContact O-CB 3.49Å; T84-R87 PolarHBondContact O-N 3.24Å; R85-R87 VanDerWaalsContact C-N 3.35Å; R87-R89 VanDerWaalsContact C-N 3.29Å; R87-R89 PolarHBondContact O-N 3.41Å; R87-V90 PolarHBondContact O-N 3.3Å; R87-V90 VanDerWaalsContact O-N 3.13Å; R87-E91 WeakPolarHBondContact CD-OE1 3.47Å; R87-E91 HydrophobicContact CG-CG 4.48Å; R87-E91 WeakPolarHBondContact CG-OE1 3.37Å; R87-E91 WeakPolarHBondContact O-CG 3.45Å; R87-E91 PolarHBondContact O-N 2.98Å
88	I	98.7	Very high	98.3	Very high	95 Å²	95	82.7 Å²	82.7	49%	0.487	42%	0.424	S	S	.	.	H	α-helix	trans	-58.4	-43.3	177.4	-67	165.8	0	0	0	110.7	T84 R85 V90 E91 A92	T84-I88 HydrophobicContact CG2-CD1 4.22Å; T84-I88 WeakPolarHBondContact O-CG1 3.37Å; T84-I88 PolarHBondContact O-N 2.92Å; R85-I88 PolarHBondContact O-N 2.94Å; I88-V90 VanDerWaalsContact C-N 3.34Å; I88-V90 PolarHBondContact O-N 3.43Å; I88-E91 PolarHBondContact O-N 2.87Å; I88-A92 PolarHBondContact O-N 3.35Å
89	R	98.7	Very high	98.3	Very high	139 Å²	139	83.5 Å²	83.5	53%	0.525	43%	0.431	S	S	.	.	H	α-helix	trans	-59.1	-44.3	176.6	-168.5	-166.3	71.5	75.3	-0.2	111.8	R85 E86 R87 F93	R85-R89 PolarHBondContact O-N 2.97Å; E86-R89 VanDerWaalsContact CD-NE 3.3Å; E86-R89 WeakPolarHBondContact O-CB 3.38Å; E86-R89 PolarHBondContact O-N 2.84Å; E86-R89 IonicContact OE1-CZ 3.88Å; E86-R89 VanDerWaalsContact OE1-CZ 3.24Å; E86-R89 IonicContact OE1-NE 2.67Å; E86-R89 PolarHBondContact OE1-NE 2.67Å; E86-R89 VanDerWaalsContact OE1-NE 3.07Å; E86-R89 IonicContact OE1-NH2 2.84Å; E86-R89 PolarHBondContact OE1-NH2 3.04Å; E86-R89 IonicContact OE2-CZ 3.24Å; E86-R89 IonicContact OE2-NE 3.07Å; E86-R89 PolarHBondContact OE2-NE 3.13Å; E86-R89 IonicContact OE2-NH2 2.63Å; R87-R89 VanDerWaalsContact C-N 3.29Å; R87-R89 PolarHBondContact O-N 3.41Å; R89-F93 WeakPolarHBondContact O-CB 3.47Å; R89-F93 PolarHBondContact O-N 3.08Å; R89-F93 VanDerWaalsContact O-N 3.09Å
90	V	98.7	Very high	98.4	Very high	53 Å²	53	79.6 Å²	79.6	32%	0.321	42%	0.421	S	S	.	.	H	α-helix	trans	-70.6	-36.4	178.7	172	0	0	0	0	111.8	E86 R87 I88 F93 N94	E86-V90 WeakPolarHBondContact O-CG2 3.48Å; E86-V90 PolarHBondContact O-N 3.37Å; R87-V90 PolarHBondContact O-N 3.3Å; R87-V90 VanDerWaalsContact O-N 3.13Å; I88-V90 VanDerWaalsContact C-N 3.34Å; I88-V90 PolarHBondContact O-N 3.43Å; V90-F93 WeakPolarHBondContact O-CB 3.5Å; V90-F93 PolarHBondContact O-N 3.4Å; V90-N94 WeakPolarHBondContact O-CB 3.36Å; V90-N94 VanDerWaalsContact O-CG 3.23Å; V90-N94 PolarHBondContact O-N 2.89Å; V90-N94 PolarHBondContact O-ND2 3.37Å
91	E	98.7	Very high	98.4	Very high	101 Å²	101	78.3 Å²	78.3	47%	0.472	41%	0.405	S	S	.	.	H	α-helix	trans	-61.6	-49.5	173.5	-75.7	169.9	-172.8	0	0	111	R87 I88 F93 N94 L95	R87-E91 WeakPolarHBondContact CD-OE1 3.47Å; R87-E91 HydrophobicContact CG-CG 4.48Å; R87-E91 WeakPolarHBondContact CG-OE1 3.37Å; R87-E91 WeakPolarHBondContact O-CG 3.45Å; R87-E91 PolarHBondContact O-N 2.98Å; I88-E91 PolarHBondContact O-N 2.87Å; E91-F93 VanDerWaalsContact C-N 3.29Å; E91-F93 PolarHBondContact O-N 3.25Å; E91-N94 PolarHBondContact O-N 3.34Å; E91-N94 VanDerWaalsContact O-N 3.08Å; E91-L95 WeakPolarHBondContact O-CG 3.5Å; E91-L95 PolarHBondContact O-N 3.1Å
92	A	98.5	Very high	98.4	Very high	57 Å²	57	83.1 Å²	83.1	47%	0.471	42%	0.419	S	S	.	.	H	α-helix	trans	-57.3	-42.6	175.1	0	0	0	0	0	112.1	I88 L95 A96	I88-A92 PolarHBondContact O-N 3.35Å; A92-L95 PolarHBondContact O-N 3.36Å; A92-A96 PolarHBondContact O-N 3.09Å; A92-A96 VanDerWaalsContact O-N 3.1Å
93	F	98.5	Very high	98.4	Very high	89 Å²	89	84.7 Å²	84.7	39%	0.39	43%	0.429	S	S	.	.	H	α-helix	trans	-61.2	-43.8	174	172.6	-90.2	0	0	0	112.5	R89 V90 E91 A96 F97 K115	R89-F93 WeakPolarHBondContact O-CB 3.47Å; R89-F93 PolarHBondContact O-N 3.08Å; R89-F93 VanDerWaalsContact O-N 3.09Å; V90-F93 WeakPolarHBondContact O-CB 3.5Å; V90-F93 PolarHBondContact O-N 3.4Å; E91-F93 VanDerWaalsContact C-N 3.29Å; E91-F93 PolarHBondContact O-N 3.25Å; F93-A96 PolarHBondContact O-N 2.63Å; F93-F97 HydrophobicContact CD1-CD2 4.11Å; F93-F97 HydrophobicContact CD1-CE2 4.38Å; F93-F97 HydrophobicContact CD2-CD2 4.47Å; F93-F97 HydrophobicContact CD2-CE2 4.32Å; F93-F97 AromaticContact CE1-CD2 3.6Å; F93-F97 HydrophobicContact CE1-CD2 3.6Å; F93-F97 AromaticContact CE1-CE2 3.54Å; F93-F97 HydrophobicContact CE1-CE2 3.54Å; F93-F97 HydrophobicContact CE1-CZ 4.42Å; F93-F97 HydrophobicContact CE2-CD2 4.05Å; F93-F97 AromaticContact CE2-CE2 3.5Å; F93-F97 HydrophobicContact CE2-CE2 3.5Å; F93-F97 AromaticContact CZ-CD2 3.61Å; F93-F97 HydrophobicContact CZ-CD2 3.61Å; F93-F97 AromaticContact CZ-CE2 3.05Å; F93-F97 HydrophobicContact CZ-CE2 3.05Å; F93-F97 AromaticContact CZ-CZ 3.88Å; F93-F97 HydrophobicContact CZ-CZ 3.88Å; F93-F97 PolarHBondContact O-N 3.07Å; F93-F97 VanDerWaalsContact O-N 3.15Å; F93-K115 HydrophobicContact CE1-CD 4.15Å
94	N	98.5	Very high	98.3	Very high	65 Å²	65	82.8 Å²	82.8	35%	0.348	41%	0.412	S	S	.	.	H	α-helix	trans	-69.8	-33.6	179.6	-70.1	-29.6	0	0	0	112.1	V90 E91 F97 A98 K115	V90-N94 WeakPolarHBondContact O-CB 3.36Å; V90-N94 VanDerWaalsContact O-CG 3.23Å; V90-N94 PolarHBondContact O-N 2.89Å; V90-N94 PolarHBondContact O-ND2 3.37Å; E91-N94 PolarHBondContact O-N 3.34Å; E91-N94 VanDerWaalsContact O-N 3.08Å; N94-F97 WeakPolarHBondContact O-CB 3.46Å; N94-F97 PolarHBondContact O-N 3.3Å; N94-A98 PolarHBondContact O-N 3.25Å; N94-K115 WeakPolarHBondContact OD1-CE 3.27Å; N94-K115 PolarHBondContact OD1-NZ 2.67Å
95	L	98.5	Very high	98.3	Very high	115 Å²	115	83 Å²	83	60%	0.602	42%	0.415	S	S	*	.	H	α-helix	trans	-61.9	-44.5	172.2	-70.8	173.9	0	0	0	111.1	E91 A92 F97 A98 E99	E91-L95 WeakPolarHBondContact O-CG 3.5Å; E91-L95 PolarHBondContact O-N 3.1Å; A92-L95 PolarHBondContact O-N 3.36Å; L95-F97 VanDerWaalsContact C-N 3.3Å; L95-F97 PolarHBondContact O-N 3.45Å; L95-A98 WeakPolarHBondContact O-CB 3.39Å; L95-A98 PolarHBondContact O-N 3.31Å; L95-E99 PolarHBondContact O-N 2.97Å
96	A	98.6	Very high	98.2	Very high	60 Å²	60	78.2 Å²	78.2	50%	0.496	40%	0.4	S	S	.	.	H	α-helix	trans	-60	-38.7	174.5	0	0	0	0	0	112.6	A92 F93 E99 L100	A92-A96 PolarHBondContact O-N 3.09Å; A92-A96 VanDerWaalsContact O-N 3.1Å; F93-A96 PolarHBondContact O-N 2.63Å; A96-E99 PolarHBondContact O-N 3.27Å; A96-L100 PolarHBondContact O-N 2.95Å
97	F	98.4	Very high	98	Very high	31 Å²	31	82.3 Å²	82.3	14%	0.136	42%	0.424	C	S	.	.	H	α-helix	trans	-64.8	-36.4	172.7	-96.6	-94.9	0	0	0	112.9	F93 N94 L95 R101 K115 I118 L119	F93-F97 HydrophobicContact CD1-CD2 4.11Å; F93-F97 HydrophobicContact CD1-CE2 4.38Å; F93-F97 HydrophobicContact CD2-CD2 4.47Å; F93-F97 HydrophobicContact CD2-CE2 4.32Å; F93-F97 AromaticContact CE1-CD2 3.6Å; F93-F97 HydrophobicContact CE1-CD2 3.6Å; F93-F97 AromaticContact CE1-CE2 3.54Å; F93-F97 HydrophobicContact CE1-CE2 3.54Å; F93-F97 HydrophobicContact CE1-CZ 4.42Å; F93-F97 HydrophobicContact CE2-CD2 4.05Å; F93-F97 AromaticContact CE2-CE2 3.5Å; F93-F97 HydrophobicContact CE2-CE2 3.5Å; F93-F97 AromaticContact CZ-CD2 3.61Å; F93-F97 HydrophobicContact CZ-CD2 3.61Å; F93-F97 AromaticContact CZ-CE2 3.05Å; F93-F97 HydrophobicContact CZ-CE2 3.05Å; F93-F97 AromaticContact CZ-CZ 3.88Å; F93-F97 HydrophobicContact CZ-CZ 3.88Å; F93-F97 PolarHBondContact O-N 3.07Å; F93-F97 VanDerWaalsContact O-N 3.15Å; N94-F97 WeakPolarHBondContact O-CB 3.46Å; N94-F97 PolarHBondContact O-N 3.3Å; L95-F97 VanDerWaalsContact C-N 3.3Å; L95-F97 PolarHBondContact O-N 3.45Å; F97-R101 WeakPolarHBondContact O-CB 3.42Å; F97-R101 PolarHBondContact O-N 2.93Å; F97-K115 HydrophobicContact CD1-CB 4.24Å; F97-K115 HydrophobicContact CD1-CG 3.94Å; F97-K115 HydrophobicContact CE1-CB 3.69Å; F97-K115 HydrophobicContact CE1-CG 3.83Å; F97-K115 HydrophobicContact CZ-CB 4.26Å; F97-K115 HydrophobicContact CZ-CG 4.39Å; F97-I118 HydrophobicContact CD1-CB 4.4Å; F97-I118 HydrophobicContact CD1-CD1 4Å; F97-I118 HydrophobicContact CD1-CG2 4.16Å; F97-I118 HydrophobicContact CE1-CB 4.48Å; F97-I118 HydrophobicContact CE1-CG2 4.38Å; F97-L119 HydrophobicContact CE1-CD2 4.37Å; F97-L119 HydrophobicContact CE1-CG 4.25Å; F97-L119 HydrophobicContact CZ-CD1 4.43Å; F97-L119 HydrophobicContact CZ-CD2 4.18Å; F97-L119 HydrophobicContact CZ-CG 4.3Å
98	A	97.9	Very high	97.8	Very high	46 Å²	46	79.2 Å²	79.2	38%	0.38	42%	0.421	S	S	.	.	H	α-helix	trans	-67.9	-41.8	176.1	0	0	0	0	0	111.6	N94 L95 R101 K102	N94-A98 PolarHBondContact O-N 3.25Å; L95-A98 WeakPolarHBondContact O-CB 3.39Å; L95-A98 PolarHBondContact O-N 3.31Å; A98-R101 PolarHBondContact O-N 2.95Å; A98-K102 WeakPolarHBondContact O-CG 3.46Å; A98-K102 PolarHBondContact O-N 3.05Å
99	E	98.2	Very high	97.4	Very high	103 Å²	103	79.6 Å²	79.6	48%	0.481	43%	0.43	S	S	.	.	H	α-helix	trans	-62.4	-46	173.7	-66.4	-48.6	132.4	0	0	111.5	L95 A96 R101 K102	L95-E99 PolarHBondContact O-N 2.97Å; A96-E99 PolarHBondContact O-N 3.27Å; E99-R101 VanDerWaalsContact C-N 3.31Å; E99-R101 PolarHBondContact O-N 2.99Å; E99-K102 PolarHBondContact O-N 3.15Å; E99-K102 IonicContact OE1-NZ 3.85Å; E99-K102 PolarHBondContact OE1-NZ 3.1Å; E99-K102 IonicContact OE2-NZ 3.78Å; E99-K102 PolarHBondContact OE2-NZ 3.13Å
100	L	98.5	Very high	97.2	Very high	57 Å²	57	79 Å²	79	30%	0.298	44%	0.437	S	S	.	.	H	α-helix	trans	-58.3	-43.4	175	179.8	57.8	0	0	0	111.6	A96 K102 L103 L104 I118 A122	A96-L100 PolarHBondContact O-N 2.95Å; L100-K102 VanDerWaalsContact C-N 3.28Å; L100-K102 PolarHBondContact O-N 3.2Å; L100-L103 PolarHBondContact O-N 3.13Å; L100-L103 VanDerWaalsContact O-N 3.16Å; L100-L104 WeakPolarHBondContact O-CG 3.48Å; L100-I118 HydrophobicContact CB-CG2 4.35Å; L100-I118 HydrophobicContact CD2-CG2 3.57Å; L100-I118 HydrophobicContact CG-CG2 3.74Å; L100-A122 HydrophobicContact CD1-CB 4.19Å; L100-A122 HydrophobicContact CD2-CB 4.45Å
101	R	97.8	Very high	97.1	Very high	42 Å²	42	81.1 Å²	81.1	16%	0.158	44%	0.442	C	S	.	.	H	α-helix	trans	-59.5	-34.6	179.5	173.2	60.3	-173.1	81.1	2.7	113.2	F97 A98 E99 L103 L104 T106 P109 K111 I118	F97-R101 WeakPolarHBondContact O-CB 3.42Å; F97-R101 PolarHBondContact O-N 2.93Å; A98-R101 PolarHBondContact O-N 2.95Å; E99-R101 VanDerWaalsContact C-N 3.31Å; E99-R101 PolarHBondContact O-N 2.99Å; R101-L103 PolarHBondContact O-N 2.9Å; R101-L104 PolarHBondContact O-N 2.69Å; R101-T106 PolarHBondContact NH2-OG1 3.36Å; R101-P109 PolarHBondContact NH2-O 2.95Å; R101-K111 PolarHBondContact NE-O 3.29Å; R101-K111 PolarHBondContact NH2-O 3.22Å; R101-I118 HydrophobicContact CB-CD1 4.06Å; R101-I118 HydrophobicContact CB-CG1 4.48Å
102	K	97.1	Very high	97	Very high	142 Å²	142	85.9 Å²	85.9	62%	0.617	46%	0.461	S	S	*	.	H	α-helix	trans	-65.2	-28.6	179.4	-68.5	171.1	-171.4	169.1	0	112.8	A98 E99 L100 L104	A98-K102 WeakPolarHBondContact O-CG 3.46Å; A98-K102 PolarHBondContact O-N 3.05Å; E99-K102 PolarHBondContact O-N 3.15Å; E99-K102 IonicContact OE1-NZ 3.85Å; E99-K102 PolarHBondContact OE1-NZ 3.1Å; E99-K102 IonicContact OE2-NZ 3.78Å; E99-K102 PolarHBondContact OE2-NZ 3.13Å; L100-K102 VanDerWaalsContact C-N 3.28Å; L100-K102 PolarHBondContact O-N 3.2Å; K102-L104 VanDerWaalsContact C-N 3.33Å
103	L	97.6	Very high	96.9	Very high	126 Å²	126	84.6 Å²	84.6	66%	0.66	45%	0.446	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.9	-13.5	-179.1	-58.3	175.4	0	0	0	113.1	L100 R101	L100-L103 PolarHBondContact O-N 3.13Å; L100-L103 VanDerWaalsContact O-N 3.16Å; R101-L103 PolarHBondContact O-N 2.9Å
104	L	97.8	Very high	96.9	Very high	11 Å²	11	82.8 Å²	82.8	6%	0.058	44%	0.444	C	S	.	.	S	Bend	trans	-88.9	131.2	-173.9	-60.8	-179.9	0	0	0	111.9	L100 R101 K102 T106 I118 L121 A122 Y125	L100-L104 WeakPolarHBondContact O-CG 3.48Å; R101-L104 PolarHBondContact O-N 2.69Å; K102-L104 VanDerWaalsContact C-N 3.33Å; L104-T106 PolarHBondContact O-N 3.21Å; L104-I118 HydrophobicContact CD1-CB 4.27Å; L104-I118 HydrophobicContact CD1-CG2 3.83Å; L104-I118 WeakPolarHBondContact CD1-O 3.34Å; L104-L121 HydrophobicContact CB-CD2 3.79Å; L104-L121 HydrophobicContact CB-CG 4.21Å; L104-L121 HydrophobicContact CD1-CB 4.12Å; L104-L121 HydrophobicContact CD1-CD2 4.05Å; L104-L121 HydrophobicContact CD1-CG 4.16Å; L104-L121 HydrophobicContact CD2-CG 4.37Å; L104-L121 HydrophobicContact CG-CD2 4.42Å; L104-L121 HydrophobicContact CG-CG 4.47Å; L104-A122 HydrophobicContact CD2-CB 3.86Å; L104-Y125 HydrophobicContact CD2-CD1 4.44Å
105	P	97.2	Very high	96.9	Very high	69 Å²	69	84.5 Å²	84.5	45%	0.448	45%	0.449	S	S	.	.			trans	-71.7	124	176.2	29.3	-34.1	0	0	0	110.5	Y125	P105-Y125 HydrophobicContact CG-CD1 4.46Å; P105-Y125 HydrophobicContact CG-CD2 3.69Å; P105-Y125 HydrophobicContact CG-CE1 4.49Å; P105-Y125 HydrophobicContact CG-CE2 3.75Å; P105-Y125 HydrophobicContact CG-CG 4.07Å
106	T	96.8	Very high	96.9	Very high	31 Å²	31	83.4 Å²	83.4	19%	0.19	44%	0.442	C	S	.	.			trans	-137.4	149.7	175.3	61.5	0	0	0	0	112.2	R101 L104 P108 P109 L113 L121	R101-T106 PolarHBondContact NH2-OG1 3.36Å; L104-T106 PolarHBondContact O-N 3.21Å; T106-P108 CarbonylContact C-O 3.37Å; T106-P108 WeakPolarHBondContact CB-O 3.49Å; T106-P108 CarbonylContact O-C 3.38Å; T106-P108 PolarHBondContact OG1-O 3.32Å; T106-P109 PolarHBondContact OG1-O 2.76Å; T106-P109 VanDerWaalsContact OG1-O 3.13Å; T106-L113 HydrophobicContact CG2-CD1 3.86Å; T106-L113 HydrophobicContact CG2-CG 4.44Å; T106-L121 HydrophobicContact CG2-CD2 3.91Å
107	L	93.9	Very high	96.9	Very high	162 Å²	162	84.3 Å²	84.3	85%	0.848	44%	0.437	S	S	*	.	S	Bend	trans	-122.4	117.7	169.1	-169	67.8	0	0	0	108.6
108	P	94.2	Very high	96.9	Very high	70 Å²	70	83.3 Å²	83.3	46%	0.455	43%	0.432	S	S	.	.	S	Bend	cis	-67.3	162	-7.1	33.2	-38.5	0	0	0	112.9	T106 D110 K111	T106-P108 CarbonylContact C-O 3.37Å; T106-P108 WeakPolarHBondContact CB-O 3.49Å; T106-P108 CarbonylContact O-C 3.38Å; T106-P108 PolarHBondContact OG1-O 3.32Å; P108-D110 WeakPolarHBondContact CB-OD1 3.4Å; P108-D110 PolarHBondContact O-N 3.31Å; P108-K111 HydrophobicContact CG-CB 4.31Å; P108-K111 VanDerWaalsContact O-CB 3.28Å; P108-K111 WeakPolarHBondContact O-CB 3.33Å; P108-K111 PolarHBondContact O-N 3.16Å; P108-K111 VanDerWaalsContact O-N 3.1Å
109	P	91.9	Very high	96.9	Very high	103 Å²	103	84.9 Å²	84.9	67%	0.669	43%	0.434	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60	-29.3	-175.8	22.4	-33.6	0	0	0	113.5	R101 T106	R101-P109 PolarHBondContact NH2-O 2.95Å; T106-P109 PolarHBondContact OG1-O 2.76Å; T106-P109 VanDerWaalsContact OG1-O 3.13Å
110	D	92.8	Very high	96.9	Very high	126 Å²	126	88 Å²	88	67%	0.674	44%	0.441	S	S	*	.	T	Hydrogen-bonded Turn	trans	-92.8	11.3	-179.7	66.1	-35.9	0	0	0	113.9	P108 K112	P108-D110 WeakPolarHBondContact CB-OD1 3.4Å; P108-D110 PolarHBondContact O-N 3.31Å; D110-K112 PolarHBondContact O-N 3.39Å; D110-K112 VanDerWaalsContact O-N 3.13Å
111	K	96.9	Very high	96.9	Very high	97 Å²	97	87.7 Å²	87.7	42%	0.422	44%	0.44	S	S	.	.			trans	-52.4	120.2	178.1	-179.4	176.1	177.3	175.9	0	111.6	R101 P108 L113	R101-K111 PolarHBondContact NE-O 3.29Å; R101-K111 PolarHBondContact NH2-O 3.22Å; P108-K111 HydrophobicContact CG-CB 4.31Å; P108-K111 VanDerWaalsContact O-CB 3.28Å; P108-K111 WeakPolarHBondContact O-CB 3.33Å; P108-K111 PolarHBondContact O-N 3.16Å; P108-K111 VanDerWaalsContact O-N 3.1Å; K111-L113 HydrophobicContact CD-CD2 3.91Å; K111-L113 HydrophobicContact CG-CD2 3.96Å; K111-L113 PolarHBondContact O-N 3.36Å
112	K	96.6	Very high	97	Very high	201 Å²	201	86.3 Å²	86.3	87%	0.874	44%	0.437	S	S	*	.			trans	-68	124.8	173	-65.9	-176.5	179.6	177.1	0	109.4	D110	D110-K112 PolarHBondContact O-N 3.39Å; D110-K112 VanDerWaalsContact O-N 3.13Å
113	L	97.3	Very high	97	Very high	30 Å²	30	84.8 Å²	84.8	16%	0.157	43%	0.434	C	S	.	.			trans	-114.5	139	177.1	-61.8	-175.5	0	0	0	109.7	T106 K111 E117 I118 L121	T106-L113 HydrophobicContact CG2-CD1 3.86Å; T106-L113 HydrophobicContact CG2-CG 4.44Å; K111-L113 HydrophobicContact CD-CD2 3.91Å; K111-L113 HydrophobicContact CG-CD2 3.96Å; K111-L113 PolarHBondContact O-N 3.36Å; L113-E117 HydrophobicContact CB-CB 4.18Å; L113-E117 HydrophobicContact CD2-CB 4.33Å; L113-I118 HydrophobicContact CB-CD1 4.31Å; L113-I118 HydrophobicContact CB-CG1 3.68Å; L113-I118 HydrophobicContact CD1-CG1 4.17Å; L113-L121 HydrophobicContact CD1-CD2 3.8Å
114	S	98	Very high	97.1	Very high	51 Å²	51	82.7 Å²	82.7	36%	0.357	43%	0.43	S	S	.	.			trans	-69.5	162.8	167.5	66.5	0	0	0	0	111.4	I116 E117 I118	S114-I116 VanDerWaalsContact C-N 3.25Å; S114-I116 PolarHBondContact O-N 3.14Å; S114-I116 WeakPolarHBondContact OG-CG2 3.28Å; S114-E117 VanDerWaalsContact CB-OE2 3.27Å; S114-E117 WeakPolarHBondContact CB-OE2 3.41Å; S114-E117 PolarHBondContact N-OE2 3.22Å; S114-E117 PolarHBondContact O-N 3.27Å; S114-E117 VanDerWaalsContact O-N 3.14Å; S114-E117 VanDerWaalsContact OG-CD 3.31Å; S114-E117 VanDerWaalsContact OG-CG 3.25Å; S114-E117 WeakPolarHBondContact OG-CG 3.34Å; S114-E117 PolarHBondContact OG-N 2.93Å; S114-E117 PolarHBondContact OG-OE2 3.35Å; S114-I118 WeakPolarHBondContact O-CG1 3.27Å; S114-I118 PolarHBondContact O-N 2.99Å
115	K	98.4	Very high	97.1	Very high	101 Å²	101	85.8 Å²	85.8	44%	0.439	44%	0.441	S	S	.	.	H	α-helix	trans	-56.4	-39.8	178.4	-69.1	-179.1	174.3	175.3	0	112.2	F93 N94 F97 L119	F93-K115 HydrophobicContact CE1-CD 4.15Å; N94-K115 WeakPolarHBondContact OD1-CE 3.27Å; N94-K115 PolarHBondContact OD1-NZ 2.67Å; F97-K115 HydrophobicContact CD1-CB 4.24Å; F97-K115 HydrophobicContact CD1-CG 3.94Å; F97-K115 HydrophobicContact CE1-CB 3.69Å; F97-K115 HydrophobicContact CE1-CG 3.83Å; F97-K115 HydrophobicContact CZ-CB 4.26Å; F97-K115 HydrophobicContact CZ-CG 4.39Å; K115-L119 WeakPolarHBondContact O-CG 3.47Å; K115-L119 PolarHBondContact O-N 3.39Å
116	I	98.6	Very high	97.1	Very high	92 Å²	92	87.3 Å²	87.3	47%	0.472	44%	0.444	S	S	.	.	H	α-helix	trans	-70.3	-37.4	178.7	-174.7	60.1	0	0	0	112.3	S114 L119 R120	S114-I116 VanDerWaalsContact C-N 3.25Å; S114-I116 PolarHBondContact O-N 3.14Å; S114-I116 WeakPolarHBondContact OG-CG2 3.28Å; I116-L119 PolarHBondContact O-N 3.44Å; I116-R120 HydrophobicContact CD1-CG 4.42Å; I116-R120 WeakPolarHBondContact O-CG 3.25Å; I116-R120 PolarHBondContact O-N 2.87Å
117	E	98.3	Very high	97.2	Very high	80 Å²	80	89.3 Å²	89.3	37%	0.374	46%	0.459	S	S	.	.	H	α-helix	trans	-66.4	-41.6	176.1	-72.7	167.3	124	0	0	111.7	L113 S114 L119 R120 L121	L113-E117 HydrophobicContact CB-CB 4.18Å; L113-E117 HydrophobicContact CD2-CB 4.33Å; S114-E117 VanDerWaalsContact CB-OE2 3.27Å; S114-E117 WeakPolarHBondContact CB-OE2 3.41Å; S114-E117 PolarHBondContact N-OE2 3.22Å; S114-E117 PolarHBondContact O-N 3.27Å; S114-E117 VanDerWaalsContact O-N 3.14Å; S114-E117 VanDerWaalsContact OG-CD 3.31Å; S114-E117 VanDerWaalsContact OG-CG 3.25Å; S114-E117 WeakPolarHBondContact OG-CG 3.34Å; S114-E117 PolarHBondContact OG-N 2.93Å; S114-E117 PolarHBondContact OG-OE2 3.35Å; E117-L119 VanDerWaalsContact C-N 3.32Å; E117-L119 PolarHBondContact O-N 3.43Å; E117-R120 PolarHBondContact O-N 2.96Å; E117-L121 VanDerWaalsContact O-CB 3.25Å; E117-L121 WeakPolarHBondContact O-CB 3.29Å; E117-L121 PolarHBondContact O-N 3.35Å
118	I	98.6	Very high	97.4	Very high	10 Å²	10	88.2 Å²	88.2	5%	0.051	45%	0.445	C	S	.	.	H	α-helix	trans	-57	-47.9	175.3	-68.9	169.7	0	0	0	110.1	F97 L100 R101 L104 L113 S114 A122	F97-I118 HydrophobicContact CD1-CB 4.4Å; F97-I118 HydrophobicContact CD1-CD1 4Å; F97-I118 HydrophobicContact CD1-CG2 4.16Å; F97-I118 HydrophobicContact CE1-CB 4.48Å; F97-I118 HydrophobicContact CE1-CG2 4.38Å; L100-I118 HydrophobicContact CB-CG2 4.35Å; L100-I118 HydrophobicContact CD2-CG2 3.57Å; L100-I118 HydrophobicContact CG-CG2 3.74Å; R101-I118 HydrophobicContact CB-CD1 4.06Å; R101-I118 HydrophobicContact CB-CG1 4.48Å; L104-I118 HydrophobicContact CD1-CB 4.27Å; L104-I118 HydrophobicContact CD1-CG2 3.83Å; L104-I118 WeakPolarHBondContact CD1-O 3.34Å; L113-I118 HydrophobicContact CB-CD1 4.31Å; L113-I118 HydrophobicContact CB-CG1 3.68Å; L113-I118 HydrophobicContact CD1-CG1 4.17Å; S114-I118 WeakPolarHBondContact O-CG1 3.27Å; S114-I118 PolarHBondContact O-N 2.99Å; I118-A122 VanDerWaalsContact O-CB 3.27Å; I118-A122 WeakPolarHBondContact O-CB 3.25Å; I118-A122 PolarHBondContact O-N 3.02Å
119	L	98.7	Very high	97.6	Very high	78 Å²	78	88.1 Å²	88.1	41%	0.408	44%	0.44	S	S	.	.	H	α-helix	trans	-63.6	-46.3	179.7	-67	174.8	0	0	0	112.2	F97 K115 I116 E117 A122 I123	F97-L119 HydrophobicContact CE1-CD2 4.37Å; F97-L119 HydrophobicContact CE1-CG 4.25Å; F97-L119 HydrophobicContact CZ-CD1 4.43Å; F97-L119 HydrophobicContact CZ-CD2 4.18Å; F97-L119 HydrophobicContact CZ-CG 4.3Å; K115-L119 WeakPolarHBondContact O-CG 3.47Å; K115-L119 PolarHBondContact O-N 3.39Å; I116-L119 PolarHBondContact O-N 3.44Å; E117-L119 VanDerWaalsContact C-N 3.32Å; E117-L119 PolarHBondContact O-N 3.43Å; L119-A122 PolarHBondContact O-N 3.43Å; L119-I123 WeakPolarHBondContact O-CG1 3.35Å; L119-I123 PolarHBondContact O-N 2.93Å; L119-I123 VanDerWaalsContact O-N 3.13Å
120	R	98.5	Very high	97.9	Very high	169 Å²	169	87.4 Å²	87.4	64%	0.638	43%	0.431	S	S	*	.	H	α-helix	trans	-61.8	-47.3	178.6	-73.5	176.2	174.5	-177	-1.6	111.7	I116 E117 A122 I123 C124	I116-R120 HydrophobicContact CD1-CG 4.42Å; I116-R120 WeakPolarHBondContact O-CG 3.25Å; I116-R120 PolarHBondContact O-N 2.87Å; E117-R120 PolarHBondContact O-N 2.96Å; R120-A122 VanDerWaalsContact C-N 3.35Å; R120-A122 PolarHBondContact O-N 3.49Å; R120-I123 PolarHBondContact O-N 3.26Å; R120-C124 PolarHBondContact O-N 2.83Å; R120-C124 PolarHBondContact O-SG 3.44Å; R120-C124 VanDerWaalsContact O-SG 3.33Å
121	L	98.2	Very high	98.1	Very high	51 Å²	51	87 Å²	87	27%	0.267	43%	0.425	S	S	.	.	H	α-helix	trans	-65.9	-37.8	-179.6	-178	60.6	0	0	0	111.7	L104 T106 L113 E117 C124 Y125	L104-L121 HydrophobicContact CB-CD2 3.79Å; L104-L121 HydrophobicContact CB-CG 4.21Å; L104-L121 HydrophobicContact CD1-CB 4.12Å; L104-L121 HydrophobicContact CD1-CD2 4.05Å; L104-L121 HydrophobicContact CD1-CG 4.16Å; L104-L121 HydrophobicContact CD2-CG 4.37Å; L104-L121 HydrophobicContact CG-CD2 4.42Å; L104-L121 HydrophobicContact CG-CG 4.47Å; T106-L121 HydrophobicContact CG2-CD2 3.91Å; L113-L121 HydrophobicContact CD1-CD2 3.8Å; E117-L121 VanDerWaalsContact O-CB 3.25Å; E117-L121 WeakPolarHBondContact O-CB 3.29Å; E117-L121 PolarHBondContact O-N 3.35Å; L121-C124 PolarHBondContact O-N 3.31Å; L121-Y125 VanDerWaalsContact O-CB 3.24Å; L121-Y125 WeakPolarHBondContact O-CB 3.24Å; L121-Y125 PolarHBondContact O-N 3.4Å
122	A	98.7	Very high	98.1	Very high	12 Å²	12	85.8 Å²	85.8	10%	0.099	43%	0.425	C	S	.	.	H	α-helix	trans	-59.9	-46.9	174.2	0	0	0	0	0	112.2	L100 L104 I118 L119 R120 Y125 I126	L100-A122 HydrophobicContact CD1-CB 4.19Å; L100-A122 HydrophobicContact CD2-CB 4.45Å; L104-A122 HydrophobicContact CD2-CB 3.86Å; I118-A122 VanDerWaalsContact O-CB 3.27Å; I118-A122 WeakPolarHBondContact O-CB 3.25Å; I118-A122 PolarHBondContact O-N 3.02Å; L119-A122 PolarHBondContact O-N 3.43Å; R120-A122 VanDerWaalsContact C-N 3.35Å; R120-A122 PolarHBondContact O-N 3.49Å; A122-Y125 PolarHBondContact O-N 3.13Å; A122-I126 VanDerWaalsContact O-CG1 3.29Å; A122-I126 WeakPolarHBondContact O-CG1 3.35Å; A122-I126 PolarHBondContact O-N 3.38Å
123	I	98.7	Very high	98.1	Very high	110 Å²	110	82.8 Å²	82.8	56%	0.564	42%	0.418	S	S	*	.	H	α-helix	trans	-59.8	-51	176.6	-66.5	163.9	0	0	0	110.2	L119 R120 Y125 I126 S127	L119-I123 WeakPolarHBondContact O-CG1 3.35Å; L119-I123 PolarHBondContact O-N 2.93Å; L119-I123 VanDerWaalsContact O-N 3.13Å; R120-I123 PolarHBondContact O-N 3.26Å; I123-Y125 VanDerWaalsContact C-N 3.29Å; I123-Y125 PolarHBondContact O-N 3.33Å; I123-I126 PolarHBondContact O-N 3.34Å; I123-S127 PolarHBondContact O-N 3.48Å; I123-S127 PolarHBondContact O-OG 2.92Å
124	C	98.1	Very high	98	Very high	83 Å²	83	88.1 Å²	88.1	56%	0.561	45%	0.447	S	S	*	.	H	α-helix	trans	-59.5	-40.2	178.7	-67.1	0	0	0	0	112.3	R120 L121 S127 Y128	R120-C124 PolarHBondContact O-N 2.83Å; R120-C124 PolarHBondContact O-SG 3.44Å; R120-C124 VanDerWaalsContact O-SG 3.33Å; L121-C124 PolarHBondContact O-N 3.31Å; C124-S127 PolarHBondContact O-N 3.35Å; C124-Y128 WeakPolarHBondContact O-CB 3.34Å; C124-Y128 PolarHBondContact O-N 2.9Å
125	Y	98.4	Very high	97	Very high	76 Å²	76	93.2 Å²	93.2	30%	0.298	48%	0.475	S	S	.	.	H	α-helix	trans	-70	-41.6	-178.5	-172.7	-133	0	0	0	112.1	L104 P105 L121 A122 I123 S127 Y128 L129	L104-Y125 HydrophobicContact CD2-CD1 4.44Å; P105-Y125 HydrophobicContact CG-CD1 4.46Å; P105-Y125 HydrophobicContact CG-CD2 3.69Å; P105-Y125 HydrophobicContact CG-CE1 4.49Å; P105-Y125 HydrophobicContact CG-CE2 3.75Å; P105-Y125 HydrophobicContact CG-CG 4.07Å; L121-Y125 VanDerWaalsContact O-CB 3.24Å; L121-Y125 WeakPolarHBondContact O-CB 3.24Å; L121-Y125 PolarHBondContact O-N 3.4Å; A122-Y125 PolarHBondContact O-N 3.13Å; I123-Y125 VanDerWaalsContact C-N 3.29Å; I123-Y125 PolarHBondContact O-N 3.33Å; Y125-S127 PolarHBondContact O-N 3.04Å; Y125-Y128 HydrophobicContact CD2-CD1 4.16Å; Y125-Y128 HydrophobicContact CE2-CD1 4.21Å; Y125-Y128 PolarHBondContact O-N 3.23Å; Y125-L129 HydrophobicContact CD1-CD1 4.2Å; Y125-L129 HydrophobicContact CD2-CG 4.22Å; Y125-L129 HydrophobicContact CE1-CD1 3.83Å; Y125-L129 HydrophobicContact CE1-CG 4.48Å; Y125-L129 HydrophobicContact CE2-CD1 4.16Å; Y125-L129 HydrophobicContact CE2-CD2 3.86Å; Y125-L129 HydrophobicContact CE2-CG 3.92Å; Y125-L129 WeakPolarHBondContact O-CG 3.38Å; Y125-L129 PolarHBondContact O-N 3.05Å
126	I	98.6	Very high	96.9	Very high	101 Å²	101	92.8 Å²	92.8	52%	0.518	48%	0.477	S	S	.	.	H	α-helix	trans	-59.1	-47.5	172.8	-67.6	164.8	0	0	0	110.4	A122 I123 Y128 L129 N130	A122-I126 VanDerWaalsContact O-CG1 3.29Å; A122-I126 WeakPolarHBondContact O-CG1 3.35Å; A122-I126 PolarHBondContact O-N 3.38Å; I123-I126 PolarHBondContact O-N 3.34Å; I126-Y128 VanDerWaalsContact C-N 3.33Å; I126-Y128 PolarHBondContact O-N 3.5Å; I126-L129 PolarHBondContact O-N 2.99Å; I126-N130 PolarHBondContact O-N 3.32Å; I126-N130 PolarHBondContact O-ND2 3.46Å
127	S	98.1	Very high	96.8	Very high	72 Å²	72	92.8 Å²	92.8	50%	0.503	48%	0.477	S	S	.	.	H	α-helix	trans	-61	-40.2	177	-63	0	0	0	0	112.8	I123 C124 Y125 N130 H131	I123-S127 PolarHBondContact O-N 3.48Å; I123-S127 PolarHBondContact O-OG 2.92Å; C124-S127 PolarHBondContact O-N 3.35Å; Y125-S127 PolarHBondContact O-N 3.04Å; S127-N130 PolarHBondContact O-N 3.48Å; S127-H131 PolarHBondContact O-N 3.12Å
128	Y	98	Very high	96.8	Very high	139 Å²	139	93.6 Å²	93.6	55%	0.545	48%	0.483	S	S	.	.	H	α-helix	trans	-62.3	-48.1	175.9	170.5	-101.1	0	0	0	111.7	C124 Y125 I126 N130 H131 V132	C124-Y128 WeakPolarHBondContact O-CB 3.34Å; C124-Y128 PolarHBondContact O-N 2.9Å; Y125-Y128 HydrophobicContact CD2-CD1 4.16Å; Y125-Y128 HydrophobicContact CE2-CD1 4.21Å; Y125-Y128 PolarHBondContact O-N 3.23Å; I126-Y128 VanDerWaalsContact C-N 3.33Å; I126-Y128 PolarHBondContact O-N 3.5Å; Y128-N130 VanDerWaalsContact C-N 3.35Å; Y128-N130 PolarHBondContact O-N 3.42Å; Y128-H131 PolarHBondContact O-N 3.39Å; Y128-V132 HydrophobicContact CD1-CG2 4.41Å; Y128-V132 HydrophobicContact CD2-CG2 4.32Å; Y128-V132 HydrophobicContact CE1-CG2 3.95Å; Y128-V132 HydrophobicContact CE2-CG2 3.84Å; Y128-V132 WeakPolarHBondContact O-CG2 3.38Å; Y128-V132 PolarHBondContact O-N 3.31Å
129	L	98	Very high	96.7	Very high	68 Å²	68	98.5 Å²	98.5	36%	0.356	51%	0.508	S	S	.	.	H	α-helix	trans	-62.2	-41.9	178.7	-67.6	178.7	0	0	0	111.8	Y125 I126 H131 V132 L133	Y125-L129 HydrophobicContact CD1-CD1 4.2Å; Y125-L129 HydrophobicContact CD2-CG 4.22Å; Y125-L129 HydrophobicContact CE1-CD1 3.83Å; Y125-L129 HydrophobicContact CE1-CG 4.48Å; Y125-L129 HydrophobicContact CE2-CD1 4.16Å; Y125-L129 HydrophobicContact CE2-CD2 3.86Å; Y125-L129 HydrophobicContact CE2-CG 3.92Å; Y125-L129 WeakPolarHBondContact O-CG 3.38Å; Y125-L129 PolarHBondContact O-N 3.05Å; I126-L129 PolarHBondContact O-N 2.99Å; L129-H131 PolarHBondContact O-N 3.27Å; L129-V132 PolarHBondContact O-N 3.48Å; L129-L133 VanDerWaalsContact O-CG 3.32Å; L129-L133 WeakPolarHBondContact O-CG 3.35Å; L129-L133 PolarHBondContact O-N 3.08Å; L129-L133 VanDerWaalsContact O-N 3.08Å
130	N	98	Very high	96.5	Very high	88 Å²	88	99.8 Å²	99.8	47%	0.471	52%	0.515	S	S	.	.	H	α-helix	trans	-59.7	-45.5	174.4	-72.2	-21.3	0	0	0	111.6	I126 S127 Y128 V132 L133 D134	I126-N130 PolarHBondContact O-N 3.32Å; I126-N130 PolarHBondContact O-ND2 3.46Å; S127-N130 PolarHBondContact O-N 3.48Å; Y128-N130 VanDerWaalsContact C-N 3.35Å; Y128-N130 PolarHBondContact O-N 3.42Å; N130-V132 VanDerWaalsContact C-N 3.32Å; N130-V132 PolarHBondContact O-N 3.22Å; N130-L133 PolarHBondContact O-N 3.03Å; N130-L133 VanDerWaalsContact O-N 3.12Å; N130-D134 PolarHBondContact O-N 3.41Å; N130-D134 VanDerWaalsContact O-N 3.08Å
131	H	97.4	Very high	96.4	Very high	119 Å²	119	95.1 Å²	95.1	55%	0.551	51%	0.506	S	S	*	.	H	α-helix	trans	-61.1	-39.9	177.1	178.6	55.7	0	0	0	112.7	S127 Y128 L129 L133 D134 V135	S127-H131 PolarHBondContact O-N 3.12Å; Y128-H131 PolarHBondContact O-N 3.39Å; L129-H131 PolarHBondContact O-N 3.27Å; H131-L133 VanDerWaalsContact C-N 3.26Å; H131-L133 PolarHBondContact O-N 3.08Å; H131-D134 PolarHBondContact O-N 2.98Å; H131-V135 WeakPolarHBondContact O-CG2 3.32Å; H131-V135 PolarHBondContact O-N 3.37Å
132	V	97.4	Very high	96.3	Very high	70 Å²	70	98.3 Å²	98.3	42%	0.424	52%	0.524	S	S	.	.	H	α-helix	trans	-65.7	-29.5	176.8	171	0	0	0	0	112.1	Y128 L129 N130	Y128-V132 HydrophobicContact CD1-CG2 4.41Å; Y128-V132 HydrophobicContact CD2-CG2 4.32Å; Y128-V132 HydrophobicContact CE1-CG2 3.95Å; Y128-V132 HydrophobicContact CE2-CG2 3.84Å; Y128-V132 WeakPolarHBondContact O-CG2 3.38Å; Y128-V132 PolarHBondContact O-N 3.31Å; L129-V132 PolarHBondContact O-N 3.48Å; N130-V132 VanDerWaalsContact C-N 3.32Å; N130-V132 PolarHBondContact O-N 3.22Å
133	L	96.9	Very high	96.1	Very high	138 Å²	138	104.9 Å²	104.9	72%	0.723	56%	0.556	S	S	*	*	H	α-helix	trans	-81.2	-23.3	177.3	-67.2	174	0	0	0	113.4	L129 N130 H131	L129-L133 VanDerWaalsContact O-CG 3.32Å; L129-L133 WeakPolarHBondContact O-CG 3.35Å; L129-L133 PolarHBondContact O-N 3.08Å; L129-L133 VanDerWaalsContact O-N 3.08Å; N130-L133 PolarHBondContact O-N 3.03Å; N130-L133 VanDerWaalsContact O-N 3.12Å; H131-L133 VanDerWaalsContact C-N 3.26Å; H131-L133 PolarHBondContact O-N 3.08Å
134	D	93.9	Very high	95.9	Very high	142 Å²	142	104.5 Å²	104.5	76%	0.759	56%	0.556	S	S	*	*	H	α-helix	trans	-84	-15.8	178.1	-69.7	-29.5	0	0	0	113.3	N130 H131	N130-D134 PolarHBondContact O-N 3.41Å; N130-D134 VanDerWaalsContact O-N 3.08Å; H131-D134 PolarHBondContact O-N 2.98Å
135	V	77.6	Confident	95.7	Very high	158 Å²	158	106.5 Å²	106.5	96%	0.958	56%	0.555	S	S	*	*			trans	-93.4	0	178.3	175.6	0	0	0	0	110.6	H131	H131-V135 WeakPolarHBondContact O-CG2 3.32Å; H131-V135 PolarHBondContact O-N 3.37Å

Retrieved 135 of 135 residues in 729.5 ms (Link to these results)

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