CD5R1_HUMAN Loading...

Cyclin-dependent kinase 5 activator 1

p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-BMAL1 heterodimer in association with altered stability and subcellular distribution.

AlphaFold DB , UniProt , Accession Q15078, Species HUMAN (Homo sapiens, Human), Gene CDK5R1, Length 307 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	55.1	Low	47.9	Very low	247 Å²	247	141.4 Å²	141.4	100%	1.217	83%	0.828	S	S	*	*				0	93.1	0	-54.5	-143.1	-107.9	0	0	105.9
2	G	45.4	Very low	47.7	Very low	73 Å²	73	147.8 Å²	147.8	75%	0.753	83%	0.828	S	S	*	*				61.3	124.6	52.3	0	0	0	0	0	110.1
3	T	49.9	Very low	47.2	Very low	119 Å²	119	151.5 Å²	151.5	73%	0.73	83%	0.83	S	S	*	*			cis	-175.2	140	8.7	-53.1	0	0	0	0	105.2	L5	T3-L5 HydrophobicContact CG2-CD2 4.46Å; T3-L5 HydrophobicContact CG2-CG 4.44Å
4	V	53.1	Low	46.5	Very low	142 Å²	142	147.2 Å²	147.2	86%	0.861	83%	0.825	S	S	*	*			trans	-155.2	94.9	152.9	-172.3	0	0	0	0	107.5
5	L	54	Low	46	Very low	154 Å²	154	146.1 Å²	146.1	81%	0.806	82%	0.823	S	S	*	*				78.5	115.5	82	-66.4	-179.1	0	0	0	115.8	T3	T3-L5 HydrophobicContact CG2-CD2 4.46Å; T3-L5 HydrophobicContact CG2-CG 4.44Å
6	S	40.8	Very low	45.8	Very low	101 Å²	101	146.3 Å²	146.3	71%	0.706	82%	0.82	S	S	*	*			trans	-83.8	151.6	175.5	164.6	0	0	0	0	111.8
7	L	53.2	Low	45.6	Very low	175 Å²	175	149.2 Å²	149.2	92%	0.916	82%	0.823	S	S	*	*			trans	-139.4	110.2	161.1	-72	174.1	0	0	0	110.4
8	S	38.8	Very low	45.4	Very low	109 Å²	109	150.7 Å²	150.7	76%	0.762	82%	0.823	S	S	*	*			trans	-106.3	133.8	160.8	-68.8	0	0	0	0	108.8
9	P	55.6	Low	45.1	Very low	136 Å²	136	151.3 Å²	151.3	88%	0.883	83%	0.825	S	S	*	*			trans	-89.5	130.9	169.8	-8.4	26.7	0	0	0	111.7
10	S	40.1	Very low	44.6	Very low	99 Å²	99	147.2 Å²	147.2	69%	0.692	82%	0.819	S	S	*	*			trans	-120.7	135.3	172	-122.9	0	0	0	0	110.5
11	Y	41.2	Very low	44.3	Very low	200 Å²	200	145 Å²	145	78%	0.784	82%	0.82	S	S	*	*			trans	62.8	129.7	147.3	-73.2	-71.1	0	0	0	123
12	R	45.4	Very low	43.6	Very low	219 Å²	219	137.2 Å²	137.2	83%	0.826	80%	0.795	S	S	*	*				109.2	117	121.1	-94.5	-165.5	-88.8	-143.5	8.5	119.5
13	K	41.3	Very low	43.5	Very low	195 Å²	195	140.6 Å²	140.6	85%	0.848	80%	0.801	S	S	*	*				90.5	108.2	126.7	-138.2	172.4	-174.3	-176.8	0	117.8
14	A	37.4	Very low	43.2	Very low	92 Å²	92	142 Å²	142	76%	0.76	81%	0.81	S	S	*	*			trans	-93.4	139	163.2	0	0	0	0	0	110
15	T	38.9	Very low	42.6	Very low	130 Å²	130	138.2 Å²	138.2	80%	0.798	80%	0.799	S	S	*	*			trans	-179.1	113.4	144.9	43.5	0	0	0	0	108.8
16	L	42.5	Very low	41.8	Very low	149 Å²	149	139.9 Å²	139.9	78%	0.78	80%	0.802	S	S	*	*			trans	-175.9	105.2	151.2	-118.1	160.1	0	0	0	108.5
17	F	43.2	Very low	41.8	Very low	196 Å²	196	144.9 Å²	144.9	86%	0.86	81%	0.807	S	S	*	*				175.7	147.5	113.6	-106	-85.6	0	0	0	111
18	E	41.2	Very low	41.8	Very low	176 Å²	176	142.7 Å²	142.7	82%	0.822	80%	0.801	S	S	*	*			trans	-98.8	158	-160.2	-167.3	163.4	117.9	0	0	111.6
19	D	39.7	Very low	41.9	Very low	162 Å²	162	141.9 Å²	141.9	87%	0.866	80%	0.801	S	S	*	*			trans	88.3	141.1	148.7	-136.2	-0.6	0	0	0	121.2
20	G	36	Very low	41.7	Very low	69 Å²	69	142.6 Å²	142.6	71%	0.711	80%	0.803	S	S	*	*			trans	121.4	94.2	160.7	0	0	0	0	0	116.8
21	A	38.1	Very low	41.9	Very low	101 Å²	101	146.7 Å²	146.7	84%	0.835	81%	0.811	S	S	*	*			trans	-74	156	175	0	0	0	0	0	114.8
22	A	39.6	Very low	42.1	Very low	84 Å²	84	145 Å²	145	69%	0.694	82%	0.815	S	S	*	*			trans	87.9	129.4	140.6	0	0	0	0	0	121
23	T	44	Very low	42	Very low	144 Å²	144	139 Å²	139	88%	0.883	81%	0.807	S	S	*	*			trans	101	128	142.9	72.8	0	0	0	0	120.9
24	V	42.6	Very low	42.4	Very low	150 Å²	150	138.8 Å²	138.8	91%	0.909	81%	0.806	S	S	*	*			trans	-63.4	142	169.9	171	0	0	0	0	111.1
25	G	41.3	Very low	42.6	Very low	62 Å²	62	141.6 Å²	141.6	64%	0.639	81%	0.808	S	S	*	*			trans	176.8	114.5	169.4	0	0	0	0	0	116.1
26	H	36.3	Very low	42.9	Very low	189 Å²	189	140.6 Å²	140.6	88%	0.875	81%	0.813	S	S	*	*			trans	-43.6	147	170.9	-96.7	-121.3	0	0	0	117.1
27	Y	41.7	Very low	42.7	Very low	205 Å²	205	142.3 Å²	142.3	80%	0.804	81%	0.814	S	S	*	*			trans	-143.6	98.1	150.4	41.5	-90.5	0	0	0	108
28	T	52.5	Low	42.8	Very low	129 Å²	129	138 Å²	138	79%	0.791	80%	0.8	S	S	*	*				69.4	121.3	93.5	59.9	0	0	0	0	116.1
29	A	42.5	Very low	43	Very low	92 Å²	92	138.3 Å²	138.3	76%	0.76	80%	0.799	S	S	*	*			trans	-54	160	179.4	0	0	0	0	0	117.7
30	V	50.6	Low	43	Very low	151 Å²	151	137.2 Å²	137.2	92%	0.915	79%	0.793	S	S	*	*			trans	-135.5	127.2	144	-90.5	0	0	0	0	110
31	Q	43.5	Very low	43.5	Very low	185 Å²	185	140.2 Å²	140.2	86%	0.864	79%	0.792	S	S	*	*			trans	-75.6	148.1	179.5	-67.9	164.9	-53.7	0	0	111.5
32	N	46	Very low	43.7	Very low	165 Å²	165	144.3 Å²	144.3	88%	0.882	79%	0.791	S	S	*	*			trans	-148.2	137.4	143.6	-150.1	2.1	0	0	0	111.4
33	S	44.1	Very low	44.3	Very low	92 Å²	92	150.4 Å²	150.4	64%	0.643	80%	0.796	S	S	*	*			trans	-109.1	144.1	-161.3	-8.2	0	0	0	0	110.7
34	K	49.6	Very low	44.6	Very low	192 Å²	192	151 Å²	151	84%	0.835	79%	0.788	S	S	*	*			trans	166	120.8	130.3	-91.4	163.7	179.8	177.4	0	113.1
35	N	40.5	Very low	44.6	Very low	151 Å²	151	149.7 Å²	149.7	81%	0.807	79%	0.786	S	S	*	*			trans	50	113.7	137	-63.7	-19.3	0	0	0	120.6
36	A	44.7	Very low	45.5	Very low	108 Å²	108	154.5 Å²	154.5	89%	0.893	80%	0.795	S	S	*	*				177.5	144.8	102.6	0	0	0	0	0	110.5
37	K	39.5	Very low	46.5	Very low	186 Å²	186	152.8 Å²	152.8	81%	0.809	79%	0.791	S	S	*	*			trans	-105.6	158	-166.5	-158.3	-176.8	-179.9	179.6	0	109.8
38	D	44	Very low	46.6	Very low	105 Å²	105	148.4 Å²	148.4	56%	0.561	79%	0.79	S	S	*	*			trans	99.9	106.1	153.7	-64.4	-59.8	0	0	0	120.7
39	K	45.6	Very low	46.4	Very low	183 Å²	183	148 Å²	148	80%	0.796	79%	0.788	S	S	*	*				74.4	107.5	118.8	-69.1	176.4	-175.6	174.8	0	121.3
40	N	41.1	Very low	47.5	Very low	139 Å²	139	150.9 Å²	150.9	74%	0.743	79%	0.789	S	S	*	*				98.2	142.3	114.9	-143.4	0.1	0	0	0	120
41	L	46.9	Very low	48	Very low	132 Å²	132	148.6 Å²	148.6	69%	0.691	78%	0.777	S	S	*	*			trans	80.3	104.9	158.7	-65.2	151.2	0	0	0	119.7
42	K	41.6	Very low	48.2	Very low	187 Å²	187	152 Å²	152	81%	0.813	78%	0.782	S	S	*	*				30.7	116.9	125.5	-71.2	177.6	173.6	175.1	0	116
43	R	51.1	Low	48.3	Very low	212 Å²	212	153 Å²	153	80%	0.8	78%	0.779	S	S	*	*				166.2	135.6	115.9	-95.8	170.9	-178.6	161	4.2	114
44	H	50.7	Low	48.8	Very low	156 Å²	156	159.5 Å²	159.5	72%	0.722	79%	0.789	S	S	*	*			trans	78.7	117.5	139.6	-55.2	-35.1	0	0	0	120.5
45	S	43.3	Very low	49	Very low	123 Å²	123	158.2 Å²	158.2	86%	0.86	79%	0.79	S	S	*	*			trans	-51.5	135	160.2	-48.6	0	0	0	0	112
46	I	60.9	Low	49.4	Very low	163 Å²	163	156.3 Å²	156.3	84%	0.836	78%	0.783	S	S	*	*			trans	-120.8	112.1	166.8	33.6	173.5	0	0	0	108.9	S48	I46-S48 PolarHBondContact O-N 3.27Å
47	I	55.4	Low	49.4	Very low	153 Å²	153	155.6 Å²	155.6	79%	0.785	78%	0.778	S	S	*	*			trans	-58.3	121.7	167.9	-64.1	169.5	0	0	0	107.9	V49	I47-V49 HydrophobicContact CG2-CG2 3.62Å; I47-V49 PolarHBondContact O-N 3.43Å
48	S	45	Very low	49.7	Very low	112 Å²	112	152.7 Å²	152.7	78%	0.783	78%	0.775	S	S	*	*			trans	-83.7	90.9	170.3	48.8	0	0	0	0	109.9	I46 L50	I46-S48 PolarHBondContact O-N 3.27Å; S48-L50 PolarHBondContact O-N 3.24Å
49	V	48.6	Very low	49.7	Very low	122 Å²	122	153.3 Å²	153.3	74%	0.739	79%	0.788	S	S	*	*			trans	-83.8	105.8	168.1	-169.3	0	0	0	0	108.1	I47	I47-V49 HydrophobicContact CG2-CG2 3.62Å; I47-V49 PolarHBondContact O-N 3.43Å
50	L	64	Low	49.6	Very low	152 Å²	152	149.1 Å²	149.1	80%	0.796	79%	0.787	S	S	*	*			trans	-79.6	124	170	-78.8	164.9	0	0	0	109.5	S48 W52	S48-L50 PolarHBondContact O-N 3.24Å; L50-W52 PolarHBondContact O-N 3.32Å
51	P	62.3	Low	49.5	Very low	102 Å²	102	152.7 Å²	152.7	66%	0.662	80%	0.796	S	S	*	*			trans	-82	115.2	177.3	30.2	-29.3	0	0	0	110.3	K53	P51-K53 PolarHBondContact O-N 2.75Å
52	W	46.5	Very low	49.5	Very low	257 Å²	257	155.7 Å²	155.7	97%	0.973	80%	0.804	S	S	*	*			trans	-68.6	93.6	163	-75.4	-10.8	0	0	0	109.5	L50	L50-W52 PolarHBondContact O-N 3.32Å
53	K	48.1	Very low	49.7	Very low	186 Å²	186	155.9 Å²	155.9	81%	0.809	81%	0.805	S	S	*	*			trans	-80.9	118.3	163.3	-76	-169.8	172.2	-173.3	0	109.3	P51 I55	P51-K53 PolarHBondContact O-N 2.75Å; K53-I55 PolarHBondContact O-N 3.36Å
54	R	54.5	Low	49.2	Very low	229 Å²	229	153.1 Å²	153.1	86%	0.864	81%	0.805	S	S	*	*			trans	-32.3	128.5	164.7	-75.8	176	-153.6	150	6.2	112.2	V56	R54-V56 HydrophobicContact CB-CG2 4.34Å
55	I	53.9	Low	49	Very low	165 Å²	165	151.2 Å²	151.2	85%	0.846	81%	0.81	S	S	*	*			trans	-109.5	101.9	151	-60.1	177.8	0	0	0	106	K53	K53-I55 PolarHBondContact O-N 3.36Å
56	V	49.9	Very low	48.8	Very low	110 Å²	110	155.2 Å²	155.2	67%	0.667	81%	0.812	S	S	*	*			trans	-95.5	108.3	163	-173.1	0	0	0	0	104.7	R54 V58	R54-V56 HydrophobicContact CB-CG2 4.34Å; V56-V58 PolarHBondContact O-N 3.03Å
57	A	44	Very low	47.9	Very low	94 Å²	94	156.9 Å²	156.9	78%	0.777	81%	0.813	S	S	*	*			trans	-81.1	104.5	173.7	0	0	0	0	0	108.7
58	V	46.3	Very low	47.4	Very low	124 Å²	124	155.8 Å²	155.8	75%	0.752	81%	0.813	S	S	*	*			trans	-71.3	128.8	169.8	172.9	0	0	0	0	108.7	V56 A60	V56-V58 PolarHBondContact O-N 3.03Å; V58-A60 PolarHBondContact O-N 3.4Å; V58-A60 VanDerWaalsContact O-N 3.13Å
59	S	43.4	Very low	47.3	Very low	119 Å²	119	159.4 Å²	159.4	83%	0.832	82%	0.818	S	S	*	*			trans	-61.9	105.4	172.6	29.6	0	0	0	0	110.9	K61	S59-K61 PolarHBondContact O-N 2.9Å
60	A	43.1	Very low	47.4	Very low	95 Å²	95	159.1 Å²	159.1	79%	0.785	82%	0.819	S	S	*	*			trans	-84	109	171.5	0	0	0	0	0	110.5	V58 K62	V58-A60 PolarHBondContact O-N 3.4Å; V58-A60 VanDerWaalsContact O-N 3.13Å; A60-K62 PolarHBondContact O-N 3.34Å
61	K	40.5	Very low	46.4	Very low	213 Å²	213	157.8 Å²	157.8	93%	0.926	81%	0.812	S	S	*	*			trans	-64.3	113	165.5	-167.2	179.8	-174.4	177.8	0	108.9	S59	S59-K61 PolarHBondContact O-N 2.9Å
62	K	46.5	Very low	46	Very low	195 Å²	195	156.6 Å²	156.6	85%	0.848	81%	0.806	S	S	*	*			trans	-139.9	102.7	170.2	-161.2	173.6	-179.5	-178.4	0	113.3	A60	A60-K62 PolarHBondContact O-N 3.34Å
63	K	46.7	Very low	46.4	Very low	192 Å²	192	147.3 Å²	147.3	84%	0.835	78%	0.78	S	S	*	*				39.5	101.4	128.7	-152.6	173.6	-177.2	179.7	0	118.1
64	N	38.6	Very low	46.5	Very low	153 Å²	153	145.8 Å²	145.8	82%	0.818	77%	0.771	S	S	*	*			trans	4.4	114.6	141.6	-148.4	3.4	0	0	0	117
65	S	48.1	Very low	46.6	Very low	116 Å²	116	142 Å²	142	81%	0.811	76%	0.763	S	S	*	*			trans	-156.9	120.6	155.1	-81.5	0	0	0	0	109.7	K67	S65-K67 PolarHBondContact O-N 3.43Å
66	K	37.9	Very low	46.9	Very low	207 Å²	207	139.4 Å²	139.4	90%	0.9	75%	0.75	S	S	*	*			trans	-60.8	114.8	179	-70.5	172.8	175	175.7	0	110.4
67	K	42.4	Very low	47.8	Very low	198 Å²	198	138.5 Å²	138.5	86%	0.861	74%	0.742	S	S	*	*			trans	-161.2	110.3	154	-137.7	170	-178.8	-179.4	0	111.4	S65	S65-K67 PolarHBondContact O-N 3.43Å
68	V	45.2	Very low	49	Very low	131 Å²	131	139.1 Å²	139.1	79%	0.794	73%	0.731	S	S	*	*			trans	42.2	104.1	149.5	-168.6	0	0	0	0	117.1	P70	V68-P70 WeakPolarHBondContact O-CD 3.41Å
69	Q	42.7	Very low	50	Low	187 Å²	187	136.9 Å²	136.9	87%	0.874	72%	0.718	S	S	*	*			trans	-67.9	133.3	170.2	-76	173	-9.2	0	0	111.9
70	P	50	Low	51.3	Low	117 Å²	117	136.4 Å²	136.4	76%	0.76	70%	0.702	S	S	*	*			trans	-103.8	125.6	139.2	30.9	-19.9	0	0	0	108.7	V68 S72	V68-P70 WeakPolarHBondContact O-CD 3.41Å; P70-S72 PolarHBondContact O-N 3.08Å
71	N	43.3	Very low	52.7	Low	123 Å²	123	136.3 Å²	136.3	66%	0.658	69%	0.688	S	S	*	*			trans	-1.3	82.7	170.5	-86.9	-11.3	0	0	0	117.9	S73 Y74	N71-S73 VanDerWaalsContact C-N 3.32Å; N71-Y74 HydrophobicContact CB-CD2 4.13Å; N71-Y74 HydrophobicContact CB-CE2 4.39Å
72	S	54.5	Low	53.8	Low	77 Å²	77	127.4 Å²	127.4	54%	0.538	65%	0.65	S	S	.	*			trans	-83	-1.4	173.6	-178.4	0	0	0	0	113.9	P70	P70-S72 PolarHBondContact O-N 3.08Å
73	S	53.9	Low	54.9	Low	62 Å²	62	122 Å²	122	43%	0.434	63%	0.631	S	S	.	*	H	α-helix	trans	-74.3	-33	-178.3	47.6	0	0	0	0	113	N71 N77	N71-S73 VanDerWaalsContact C-N 3.32Å; S73-N77 PolarHBondContact O-N 3.06Å; S73-N77 PolarHBondContact O-ND2 3.47Å
74	Y	51.3	Low	55.9	Low	155 Å²	155	116.8 Å²	116.8	61%	0.608	61%	0.61	S	S	*	*	H	α-helix	trans	-71.6	-41.3	-175.5	-70.8	-83.5	0	0	0	113.4	N71 N77 I78	N71-Y74 HydrophobicContact CB-CD2 4.13Å; N71-Y74 HydrophobicContact CB-CE2 4.39Å; Y74-N77 PolarHBondContact O-N 2.87Å; Y74-I78 WeakPolarHBondContact O-CG1 3.49Å; Y74-I78 PolarHBondContact O-N 2.75Å; Y74-I78 VanDerWaalsContact O-N 3.13Å
75	Q	56	Low	57.1	Low	150 Å²	150	112.8 Å²	112.8	70%	0.701	59%	0.588	S	S	*	*	H	α-helix	trans	-64.2	-43	178.6	-94.8	-169	-47	0	0	112.2	N77 I78 T79	Q75-N77 VanDerWaalsContact C-N 3.29Å; Q75-N77 PolarHBondContact O-N 3.45Å; Q75-I78 PolarHBondContact O-N 3.28Å; Q75-T79 PolarHBondContact O-N 2.87Å; Q75-T79 VanDerWaalsContact O-N 3.11Å; Q75-T79 PolarHBondContact O-OG1 3.32Å
76	N	61.3	Low	57.7	Low	109 Å²	109	108.9 Å²	108.9	58%	0.583	56%	0.558	S	S	*	*	H	α-helix	trans	-63	-36.6	178.1	-77.4	-26.7	0	0	0	112.4	H80	N76-H80 WeakPolarHBondContact O-CB 3.5Å; N76-H80 PolarHBondContact O-N 3.46Å
77	N	68.2	Low	58.7	Low	91 Å²	91	106.3 Å²	106.3	49%	0.487	55%	0.547	S	S	.	.	H	α-helix	trans	-65.4	-41.9	175.9	-74.6	-34.4	0	0	0	111.6	S73 Y74 Q75 H80 L81	S73-N77 PolarHBondContact O-N 3.06Å; S73-N77 PolarHBondContact O-ND2 3.47Å; Y74-N77 PolarHBondContact O-N 2.87Å; Q75-N77 VanDerWaalsContact C-N 3.29Å; Q75-N77 PolarHBondContact O-N 3.45Å; N77-H80 PolarHBondContact O-N 3.14Å; N77-L81 WeakPolarHBondContact O-CB 3.4Å; N77-L81 WeakPolarHBondContact O-CD1 3.49Å; N77-L81 WeakPolarHBondContact O-CG 3.32Å; N77-L81 PolarHBondContact O-N 2.95Å
78	I	68.1	Low	59.5	Low	108 Å²	108	103.5 Å²	103.5	55%	0.554	54%	0.535	S	S	*	.	H	α-helix	trans	-63.9	-46.3	179.5	-65	163.3	0	0	0	110.7	Y74 Q75 H80 L81 N82	Y74-I78 WeakPolarHBondContact O-CG1 3.49Å; Y74-I78 PolarHBondContact O-N 2.75Å; Y74-I78 VanDerWaalsContact O-N 3.13Å; Q75-I78 PolarHBondContact O-N 3.28Å; I78-H80 VanDerWaalsContact C-N 3.31Å; I78-H80 PolarHBondContact O-N 2.96Å; I78-L81 PolarHBondContact O-N 2.74Å; I78-N82 WeakPolarHBondContact O-CB 3.32Å; I78-N82 PolarHBondContact O-N 3.35Å
79	T	68.7	Low	60	Low	76 Å²	76	99.3 Å²	99.3	47%	0.466	51%	0.511	S	S	.	.	H	α-helix	trans	-65.8	-35.4	178.9	-29.7	0	0	0	0	111.9	Q75 N83	Q75-T79 PolarHBondContact O-N 2.87Å; Q75-T79 VanDerWaalsContact O-N 3.11Å; Q75-T79 PolarHBondContact O-OG1 3.32Å; T79-N83 PolarHBondContact O-N 2.83Å; T79-N83 VanDerWaalsContact O-N 3.15Å; T79-N83 PolarHBondContact O-ND2 3.36Å
80	H	70.2	Confident	60.6	Low	109 Å²	109	92.6 Å²	92.6	51%	0.505	48%	0.481	S	S	.	.	H	α-helix	trans	-66	-47.9	174.3	-174.5	-88.5	0	0	0	111.6	N76 N77 I78 N82 N83 E84	N76-H80 WeakPolarHBondContact O-CB 3.5Å; N76-H80 PolarHBondContact O-N 3.46Å; N77-H80 PolarHBondContact O-N 3.14Å; I78-H80 VanDerWaalsContact C-N 3.31Å; I78-H80 PolarHBondContact O-N 2.96Å; H80-N82 VanDerWaalsContact C-N 3.34Å; H80-N82 PolarHBondContact O-N 3.1Å; H80-N83 WeakPolarHBondContact O-CB 3.26Å; H80-N83 PolarHBondContact O-N 2.82Å; H80-E84 VanDerWaalsContact CE1-CD 3.45Å; H80-E84 IonicContact CE1-OE1 3.52Å; H80-E84 IonicContact CE1-OE2 3.79Å; H80-E84 IonicContact ND1-OE2 3.76Å; H80-E84 PolarHBondContact O-N 3.16Å
81	L	71.8	Confident	60.8	Low	93 Å²	93	90.6 Å²	90.6	49%	0.487	47%	0.47	S	S	.	.	H	α-helix	trans	-61.5	-40.1	177.6	-72.6	161	0	0	0	111.8	N77 I78 N83 E84 N85	N77-L81 WeakPolarHBondContact O-CB 3.4Å; N77-L81 WeakPolarHBondContact O-CD1 3.49Å; N77-L81 WeakPolarHBondContact O-CG 3.32Å; N77-L81 PolarHBondContact O-N 2.95Å; I78-L81 PolarHBondContact O-N 2.74Å; L81-N83 VanDerWaalsContact C-N 3.34Å; L81-N83 PolarHBondContact O-N 3.34Å; L81-E84 PolarHBondContact O-N 3.07Å; L81-N85 PolarHBondContact O-N 3.43Å; L81-N85 PolarHBondContact O-ND2 2.99Å; L81-N85 VanDerWaalsContact O-ND2 3.12Å
82	N	65.1	Low	61.2	Low	26 Å²	26	85.6 Å²	85.6	14%	0.139	44%	0.444	C	S	.	.	H	α-helix	trans	-64.1	-40.6	177	-153	0.1	0	0	0	111	I78 H80 E84 N85 L86 D192	I78-N82 WeakPolarHBondContact O-CB 3.32Å; I78-N82 PolarHBondContact O-N 3.35Å; H80-N82 VanDerWaalsContact C-N 3.34Å; H80-N82 PolarHBondContact O-N 3.1Å; N82-E84 PolarHBondContact O-N 3.28Å; N82-N85 PolarHBondContact O-N 2.98Å; N82-L86 PolarHBondContact O-N 3.04Å; N82-D192 PolarHBondContact ND2-OD2 3.22Å
83	N	69.8	Low	61.2	Low	83 Å²	83	83.4 Å²	83.4	44%	0.444	43%	0.431	S	S	.	.	H	α-helix	trans	-65.6	-34.6	172.8	-81	-56.6	0	0	0	113.5	T79 H80 L81 L86 K87	T79-N83 PolarHBondContact O-N 2.83Å; T79-N83 VanDerWaalsContact O-N 3.15Å; T79-N83 PolarHBondContact O-ND2 3.36Å; H80-N83 WeakPolarHBondContact O-CB 3.26Å; H80-N83 PolarHBondContact O-N 2.82Å; L81-N83 VanDerWaalsContact C-N 3.34Å; L81-N83 PolarHBondContact O-N 3.34Å; N83-L86 WeakPolarHBondContact O-CB 3.41Å; N83-L86 PolarHBondContact O-N 3.47Å; N83-K87 PolarHBondContact O-N 3.5Å
84	E	66.8	Low	61.1	Low	82 Å²	82	84.3 Å²	84.3	38%	0.383	43%	0.431	S	S	.	.	H	α-helix	trans	-69.8	-39.7	174.6	-72.2	-164.9	130.3	0	0	112.3	H80 L81 N82 L86 K87 K88	H80-E84 VanDerWaalsContact CE1-CD 3.45Å; H80-E84 IonicContact CE1-OE1 3.52Å; H80-E84 IonicContact CE1-OE2 3.79Å; H80-E84 IonicContact ND1-OE2 3.76Å; H80-E84 PolarHBondContact O-N 3.16Å; L81-E84 PolarHBondContact O-N 3.07Å; N82-E84 PolarHBondContact O-N 3.28Å; E84-L86 VanDerWaalsContact C-N 3.31Å; E84-L86 PolarHBondContact O-N 2.82Å; E84-K87 WeakPolarHBondContact O-CB 3.45Å; E84-K87 PolarHBondContact O-N 3.42Å; E84-K88 PolarHBondContact O-N 2.98Å; E84-K88 VanDerWaalsContact O-N 3.11Å
85	N	63.2	Low	61.1	Low	69 Å²	69	80.2 Å²	80.2	37%	0.369	42%	0.419	S	S	.	.	H	α-helix	trans	-62	-40.3	172.5	-74.8	-46.5	0	0	0	111.2	L81 N82 K87 K88 S89	L81-N85 PolarHBondContact O-N 3.43Å; L81-N85 PolarHBondContact O-ND2 2.99Å; L81-N85 VanDerWaalsContact O-ND2 3.12Å; N82-N85 PolarHBondContact O-N 2.98Å; N85-K87 VanDerWaalsContact C-N 3.29Å; N85-K87 PolarHBondContact O-N 3.13Å; N85-K88 PolarHBondContact O-N 3.31Å; N85-S89 PolarHBondContact O-N 2.92Å; N85-S89 PolarHBondContact O-OG 2.94Å
86	L	61.7	Low	60.7	Low	33 Å²	33	76.9 Å²	76.9	17%	0.173	41%	0.412	C	S	.	.	H	α-helix	trans	-55.5	-43.5	172.8	-169.9	77.5	0	0	0	111.8	N82 N83 E84 K88 L90	N82-L86 PolarHBondContact O-N 3.04Å; N83-L86 WeakPolarHBondContact O-CB 3.41Å; N83-L86 PolarHBondContact O-N 3.47Å; E84-L86 VanDerWaalsContact C-N 3.31Å; E84-L86 PolarHBondContact O-N 2.82Å; L86-K88 VanDerWaalsContact C-N 3.34Å; L86-K88 PolarHBondContact O-N 3.21Å; L86-L90 HydrophobicContact CD1-CD1 4.16Å; L86-L90 HydrophobicContact CD2-CD1 4.43Å; L86-L90 HydrophobicContact CG-CD1 3.84Å; L86-L90 VanDerWaalsContact O-CB 3.27Å; L86-L90 WeakPolarHBondContact O-CB 3.26Å; L86-L90 WeakPolarHBondContact O-CG 3.43Å; L86-L90 PolarHBondContact O-N 3.39Å
87	K	59.4	Low	59.9	Low	154 Å²	154	76.6 Å²	76.6	67%	0.67	42%	0.415	S	S	*	.	H	α-helix	trans	-65	-36.2	177	-71.4	176.6	-179.5	174.4	0	112.6	N83 E84 N85 S91	N83-K87 PolarHBondContact O-N 3.5Å; E84-K87 WeakPolarHBondContact O-CB 3.45Å; E84-K87 PolarHBondContact O-N 3.42Å; N85-K87 VanDerWaalsContact C-N 3.29Å; N85-K87 PolarHBondContact O-N 3.13Å; K87-S91 PolarHBondContact O-N 3.07Å; K87-S91 VanDerWaalsContact O-N 3.15Å
88	K	59.2	Low	59	Low	139 Å²	139	78.9 Å²	78.9	60%	0.604	42%	0.42	S	S	*	.	H	α-helix	trans	-71.5	-47.8	179	-69.4	174.8	-175.9	171.9	0	111.7	E84 N85 L86 L90 S91	E84-K88 PolarHBondContact O-N 2.98Å; E84-K88 VanDerWaalsContact O-N 3.11Å; N85-K88 PolarHBondContact O-N 3.31Å; L86-K88 VanDerWaalsContact C-N 3.34Å; L86-K88 PolarHBondContact O-N 3.21Å; K88-L90 VanDerWaalsContact C-N 3.26Å; K88-L90 PolarHBondContact O-N 3.26Å; K88-S91 WeakPolarHBondContact O-CB 3.45Å; K88-S91 PolarHBondContact O-N 2.84Å; K88-S91 PolarHBondContact O-OG 2.99Å
89	S	54.7	Low	57.9	Low	43 Å²	43	75.7 Å²	75.7	30%	0.301	41%	0.41	S	S	.	.	H	α-helix	trans	-65.1	-29.5	177.9	-55.7	0	0	0	0	112.5	N85	N85-S89 PolarHBondContact O-N 2.92Å; N85-S89 PolarHBondContact O-OG 2.94Å
90	L	56.1	Low	56.5	Low	46 Å²	46	80.2 Å²	80.2	24%	0.241	43%	0.426	C	S	.	.	T	Hydrogen-bonded Turn	trans	-89.5	1.9	174.1	-62.3	175.8	0	0	0	113.7	L86 K88 C92 A93 N94	L86-L90 HydrophobicContact CD1-CD1 4.16Å; L86-L90 HydrophobicContact CD2-CD1 4.43Å; L86-L90 HydrophobicContact CG-CD1 3.84Å; L86-L90 VanDerWaalsContact O-CB 3.27Å; L86-L90 WeakPolarHBondContact O-CB 3.26Å; L86-L90 WeakPolarHBondContact O-CG 3.43Å; L86-L90 PolarHBondContact O-N 3.39Å; K88-L90 VanDerWaalsContact C-N 3.26Å; K88-L90 PolarHBondContact O-N 3.26Å; L90-C92 VanDerWaalsContact C-N 3.25Å; L90-C92 PolarHBondContact O-N 3.49Å; L90-A93 HydrophobicContact CD2-CB 4.5Å; L90-A93 CarbonylContact O-C 3.56Å; L90-A93 WeakPolarHBondContact O-CA 3.5Å; L90-A93 PolarHBondContact O-N 2.91Å; L90-N94 PolarHBondContact O-N 3.5Å; L90-N94 PolarHBondContact O-ND2 3.35Å
91	S	53.9	Low	55.2	Low	75 Å²	75	80.1 Å²	80.1	52%	0.524	44%	0.435	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62.9	-31.4	-172.3	66.2	0	0	0	0	113.1	K87 K88	K87-S91 PolarHBondContact O-N 3.07Å; K87-S91 VanDerWaalsContact O-N 3.15Å; K88-S91 WeakPolarHBondContact O-CB 3.45Å; K88-S91 PolarHBondContact O-N 2.84Å; K88-S91 PolarHBondContact O-OG 2.99Å
92	C	51.4	Low	54.4	Low	18 Å²	18	81.1 Å²	81.1	12%	0.122	45%	0.447	C	S	.	.	T	Hydrogen-bonded Turn	trans	-78.9	-22.9	172.6	53.5	0	0	0	0	113.5	L90	L90-C92 VanDerWaalsContact C-N 3.25Å; L90-C92 PolarHBondContact O-N 3.49Å
93	A	54.8	Low	53.9	Low	30 Å²	30	85.8 Å²	85.8	25%	0.248	48%	0.479	C	S	.	.	T	Hydrogen-bonded Turn	trans	-87.7	-18	177.7	0	0	0	0	0	113.4	L90 L95 A199	L90-A93 HydrophobicContact CD2-CB 4.5Å; L90-A93 CarbonylContact O-C 3.56Å; L90-A93 WeakPolarHBondContact O-CA 3.5Å; L90-A93 PolarHBondContact O-N 2.91Å; A93-L95 VanDerWaalsContact C-N 3.28Å; A93-L95 WeakPolarHBondContact O-CD1 3.28Å; A93-L95 PolarHBondContact O-N 3.1Å; A93-A199 HydrophobicContact CB-CB 3.75Å
94	N	50.8	Low	52.8	Low	82 Å²	82	86.3 Å²	86.3	44%	0.439	50%	0.495	S	S	.	.			trans	-77	80.3	169.7	-88.1	-60.6	0	0	0	110	L90 S96 T97	L90-N94 PolarHBondContact O-N 3.5Å; L90-N94 PolarHBondContact O-ND2 3.35Å; N94-S96 PolarHBondContact O-N 3.31Å; N94-T97 PolarHBondContact O-N 3.47Å; N94-T97 PolarHBondContact O-OG1 3.37Å
95	L	51.8	Low	52	Low	69 Å²	69	91.1 Å²	91.1	36%	0.361	52%	0.517	S	S	.	.	G	3₁₀ helix	trans	-57.6	-4	173.3	-90.6	72.7	0	0	0	113.9	A93 T97 F98 V144	A93-L95 VanDerWaalsContact C-N 3.28Å; A93-L95 WeakPolarHBondContact O-CD1 3.28Å; A93-L95 PolarHBondContact O-N 3.1Å; L95-T97 PolarHBondContact O-N 3.25Å; L95-F98 PolarHBondContact O-N 2.92Å; L95-V144 HydrophobicContact CD2-CG2 4.31Å
96	S	47.2	Very low	51.8	Low	80 Å²	80	93.6 Å²	93.6	56%	0.559	54%	0.537	S	S	*	.	G	3₁₀ helix	trans	-62.8	-24	171.1	48.2	0	0	0	0	113.5	N94 F98 A99	N94-S96 PolarHBondContact O-N 3.31Å; S96-F98 VanDerWaalsContact C-N 3.28Å; S96-F98 PolarHBondContact O-N 2.88Å; S96-A99 WeakPolarHBondContact O-CB 3.39Å; S96-A99 PolarHBondContact O-N 3.43Å
97	T	45.8	Very low	51.5	Low	103 Å²	103	98.1 Å²	98.1	63%	0.632	57%	0.568	S	S	*	*	G	3₁₀ helix	trans	-74.7	-17.2	-177	-47.8	0	0	0	0	113.2	N94 L95 A99	N94-T97 PolarHBondContact O-N 3.47Å; N94-T97 PolarHBondContact O-OG1 3.37Å; L95-T97 PolarHBondContact O-N 3.25Å; T97-A99 PolarHBondContact O-N 3Å
98	F	48.4	Very low	51.3	Low	139 Å²	139	95 Å²	95	61%	0.61	57%	0.572	S	S	*	*	G	3₁₀ helix	trans	-83	3.7	173.3	-72	-78.8	0	0	0	113.8	L95 S96 P279	L95-F98 PolarHBondContact O-N 2.92Å; S96-F98 VanDerWaalsContact C-N 3.28Å; S96-F98 PolarHBondContact O-N 2.88Å; F98-P279 HydrophobicContact CE2-CB 3.62Å; F98-P279 HydrophobicContact CE2-CG 4.03Å; F98-P279 HydrophobicContact CZ-CB 3.5Å; F98-P279 VanDerWaalsContact CZ-CB 3.5Å; F98-P279 HydrophobicContact CZ-CG 3.69Å
99	A	45.3	Very low	51.4	Low	40 Å²	40	94.1 Å²	94.1	33%	0.331	58%	0.58	S	S	.	*	G	3₁₀ helix	trans	-97.8	2.9	-176.5	0	0	0	0	0	114.7	S96 T97	S96-A99 WeakPolarHBondContact O-CB 3.39Å; S96-A99 PolarHBondContact O-N 3.43Å; T97-A99 PolarHBondContact O-N 3Å
100	Q	39.3	Very low	51.5	Low	171 Å²	171	97.9 Å²	97.9	80%	0.799	60%	0.603	S	S	*	*	P	Polyproline II helix	trans	-101.6	121.8	177.7	-76.8	-166.2	-48.8	0	0	111.9
101	P	42.1	Very low	51.4	Low	108 Å²	108	100.6 Å²	100.6	70%	0.701	63%	0.632	S	S	*	*	P	Polyproline II helix	trans	-58	149.7	161.3	-13.6	27.1	0	0	0	109.5
102	P	56.6	Low	51	Low	114 Å²	114	102.4 Å²	102.4	74%	0.74	65%	0.645	S	S	*	*	P	Polyproline II helix	trans	-52.9	141.7	171.3	22.4	-31.2	0	0	0	109.5	A104	P102-A104 PolarHBondContact O-N 3.24Å
103	P	54.1	Low	50.7	Low	123 Å²	123	110.1 Å²	110.1	80%	0.799	68%	0.679	S	S	*	*	P	Polyproline II helix	trans	-58.6	116	-179.8	22.9	-30.6	0	0	0	108.8	Q105	P103-Q105 PolarHBondContact O-N 2.98Å
104	A	46.3	Very low	50.3	Low	95 Å²	95	116 Å²	116	79%	0.785	71%	0.706	S	S	*	*	P	Polyproline II helix	trans	-58.2	123.8	173.3	0	0	0	0	0	108.5	P102	P102-A104 PolarHBondContact O-N 3.24Å
105	Q	49.2	Very low	50	Low	183 Å²	183	118 Å²	118	86%	0.855	73%	0.726	S	S	*	*	P	Polyproline II helix	trans	-54.6	137.7	174	-73.3	176.7	-54.5	0	0	110	P103	P103-Q105 PolarHBondContact O-N 2.98Å
106	P	60.4	Low	49.5	Very low	120 Å²	120	118.1 Å²	118.1	78%	0.779	74%	0.744	S	S	*	*	P	Polyproline II helix	trans	-66	135.5	175.2	25.8	-30.6	0	0	0	109.9
107	P	54.1	Low	49.3	Very low	128 Å²	128	119.4 Å²	119.4	83%	0.831	75%	0.753	S	S	*	*	P	Polyproline II helix	trans	-70.9	137.4	176	28.3	-31	0	0	0	110.4
108	A	56	Low	49.5	Very low	90 Å²	90	122.6 Å²	122.6	74%	0.744	76%	0.761	S	S	*	*	P	Polyproline II helix	trans	-61.2	148	176.8	0	0	0	0	0	112
109	P	61.1	Low	49.3	Very low	120 Å²	120	121.9 Å²	121.9	78%	0.779	77%	0.768	S	S	*	*	P	Polyproline II helix	trans	-73	140.4	-177.6	29.6	-33.1	0	0	0	111.4
110	P	56.9	Low	49	Very low	122 Å²	122	124.1 Å²	124.1	79%	0.792	80%	0.795	S	S	*	*	P	Polyproline II helix	trans	-77.5	135.1	175.9	30.1	-30.8	0	0	0	111	S112	P110-S112 PolarHBondContact O-N 2.85Å
111	A	53.5	Low	48.9	Very low	103 Å²	103	119.9 Å²	119.9	85%	0.851	80%	0.797	S	S	*	*	P	Polyproline II helix	trans	-68.9	125.1	173.9	0	0	0	0	0	110.9
112	S	45.2	Very low	48.9	Very low	112 Å²	112	120.6 Å²	120.6	78%	0.783	81%	0.805	S	S	*	*	P	Polyproline II helix	trans	-74.8	129.5	168.5	-56.5	0	0	0	0	110.3	P110	P110-S112 PolarHBondContact O-N 2.85Å
113	Q	46.1	Very low	48.4	Very low	181 Å²	181	120.9 Å²	120.9	85%	0.846	81%	0.81	S	S	*	*			trans	-163.1	102.1	142.7	-106.9	161.7	41.3	0	0	113.3
114	L	45.8	Very low	48	Very low	153 Å²	153	120.2 Å²	120.2	80%	0.801	81%	0.808	S	S	*	*			trans	55.5	109.4	132.5	-72.7	118.1	0	0	0	122.5
115	S	44.2	Very low	48.3	Very low	124 Å²	124	122 Å²	122	87%	0.867	81%	0.808	S	S	*	*				55.9	129.4	120.5	-75.3	0	0	0	0	123.8
116	G	41.1	Very low	48.1	Very low	72 Å²	72	122.2 Å²	122.2	74%	0.742	81%	0.807	S	S	*	*			trans	124	81.5	144.4	0	0	0	0	0	114
117	S	43.6	Very low	47.2	Very low	107 Å²	107	126.6 Å²	126.6	75%	0.748	81%	0.813	S	S	*	*				84.6	130.9	84.9	-163.4	0	0	0	0	115.1
118	Q	50.1	Low	46.8	Very low	169 Å²	169	124.5 Å²	124.5	79%	0.79	81%	0.807	S	S	*	*			trans	81.8	139.8	163.1	-47.2	-165.4	74.6	0	0	116.8
119	T	43.8	Very low	46.2	Very low	125 Å²	125	125.9 Å²	125.9	77%	0.767	81%	0.808	S	S	*	*			cis	-173.8	142.7	-9.4	22.7	0	0	0	0	105.8
120	G	38.5	Very low	45.8	Very low	87 Å²	87	128.6 Å²	128.6	90%	0.897	81%	0.81	S	S	*	*			trans	79.9	139.4	144.2	0	0	0	0	0	120.5
121	G	38.4	Very low	45.4	Very low	82 Å²	82	128.1 Å²	128.1	85%	0.845	81%	0.807	S	S	*	*			trans	135.7	91.9	150.8	0	0	0	0	0	116.7
122	S	42.7	Very low	44.9	Very low	123 Å²	123	127.9 Å²	127.9	86%	0.86	81%	0.805	S	S	*	*			trans	-58.2	145.5	174.6	-45.7	0	0	0	0	115.6
123	S	45.6	Very low	45.1	Very low	120 Å²	120	129.1 Å²	129.1	84%	0.839	81%	0.807	S	S	*	*				173.4	128.7	120	58	0	0	0	0	114.6
124	S	45.9	Very low	45.3	Very low	109 Å²	109	126.5 Å²	126.5	76%	0.762	80%	0.804	S	S	*	*			trans	-33.6	137.1	163.7	-179	0	0	0	0	117.7
125	V	51.1	Low	45.5	Very low	131 Å²	131	124.9 Å²	124.9	79%	0.794	81%	0.805	S	S	*	*			trans	-164.3	115.9	130.6	177.2	0	0	0	0	112.2
126	K	46.2	Very low	45.7	Very low	189 Å²	189	123.8 Å²	123.8	82%	0.822	80%	0.804	S	S	*	*			trans	32.8	113.8	138.1	-53.4	176.3	-179.9	177.2	0	123
127	K	41.2	Very low	46	Very low	212 Å²	212	123.8 Å²	123.8	92%	0.922	80%	0.804	S	S	*	*				57.4	111	113	-152	173.7	-166.9	175.9	0	120.7
128	A	45.7	Very low	46.4	Very low	83 Å²	83	124.6 Å²	124.6	69%	0.686	81%	0.805	S	S	*	*			trans	-156.1	140.7	138.1	0	0	0	0	0	111.1
129	P	43.7	Very low	46.5	Very low	119 Å²	119	122.4 Å²	122.4	77%	0.773	81%	0.805	S	S	*	*			trans	-96.4	139.8	-172.4	36	-29.4	0	0	0	112.7
130	H	51.7	Low	46.6	Very low	178 Å²	178	126 Å²	126	82%	0.824	81%	0.81	S	S	*	*			trans	-129.9	148.3	168.6	-75.6	-67.1	0	0	0	110.8
131	P	48.6	Very low	47	Very low	111 Å²	111	131.1 Å²	131.1	72%	0.721	80%	0.803	S	S	*	*			trans	-82.3	150.8	-139.4	32	-34.8	0	0	0	113.6	V133	P131-V133 PolarHBondContact O-N 3.14Å; P131-V133 VanDerWaalsContact O-N 3.13Å
132	A	44.6	Very low	47.7	Very low	99 Å²	99	132.9 Å²	132.9	82%	0.818	80%	0.797	S	S	*	*			trans	-57.4	113.1	173.6	0	0	0	0	0	110.7	T134	A132-T134 PolarHBondContact O-N 3.36Å; A132-T134 VanDerWaalsContact O-N 3.13Å
133	V	49.7	Very low	48.2	Very low	137 Å²	137	133.4 Å²	133.4	83%	0.83	79%	0.788	S	S	*	*			trans	-67.1	107	166.6	179.5	0	0	0	0	107	P131 S135	P131-V133 PolarHBondContact O-N 3.14Å; P131-V133 VanDerWaalsContact O-N 3.13Å; V133-S135 PolarHBondContact O-N 3.33Å
134	T	50.3	Low	49	Very low	126 Å²	126	130.1 Å²	130.1	77%	0.773	76%	0.763	S	S	*	*			trans	-51.3	121.9	170.2	38.9	0	0	0	0	109.9	A132 A136	A132-T134 PolarHBondContact O-N 3.36Å; A132-T134 VanDerWaalsContact O-N 3.13Å; T134-A136 PolarHBondContact O-N 2.79Å; T134-A136 VanDerWaalsContact O-N 3.14Å
135	S	48.5	Very low	50.6	Low	119 Å²	119	132.3 Å²	132.3	83%	0.832	76%	0.761	S	S	*	*			trans	-51.2	112.5	177.1	-33.4	0	0	0	0	110	V133 G137	V133-S135 PolarHBondContact O-N 3.33Å; S135-G137 PolarHBondContact O-N 3.38Å; S135-G137 VanDerWaalsContact O-N 3.11Å
136	A	49.5	Very low	52.2	Low	101 Å²	101	126.8 Å²	126.8	84%	0.835	73%	0.73	S	S	*	*			trans	-55.2	115.3	174.2	0	0	0	0	0	109.6	T134 T138	T134-A136 PolarHBondContact O-N 2.79Å; T134-A136 VanDerWaalsContact O-N 3.14Å; A136-T138 PolarHBondContact O-N 3.31Å
137	G	47.5	Very low	54.5	Low	73 Å²	73	120.8 Å²	120.8	75%	0.753	71%	0.711	S	S	*	*			trans	-61.2	128.9	178.7	0	0	0	0	0	111.1	S135	S135-G137 PolarHBondContact O-N 3.38Å; S135-G137 VanDerWaalsContact O-N 3.11Å
138	T	52.1	Low	57.2	Low	123 Å²	123	112.1 Å²	112.1	76%	0.755	68%	0.676	S	S	*	*			trans	-54.3	131.9	167.6	51	0	0	0	0	109.6	A136 K140	A136-T138 PolarHBondContact O-N 3.31Å; T138-K140 PolarHBondContact O-N 2.71Å
139	P	50.4	Low	59.6	Low	124 Å²	124	111.9 Å²	111.9	81%	0.805	67%	0.669	S	S	*	*			trans	-59.5	115.5	176.1	22.5	-30.7	0	0	0	109	R141	P139-R141 PolarHBondContact O-N 3.49Å
140	K	46.9	Very low	62.1	Low	199 Å²	199	110 Å²	110	87%	0.865	65%	0.65	S	S	*	*			trans	-59.3	111.8	173.6	-73.8	178.2	178.7	173.1	0	107.5	T138 V142	T138-K140 PolarHBondContact O-N 2.71Å; K140-V142 PolarHBondContact O-N 3.38Å; K140-V142 VanDerWaalsContact O-N 3.1Å
141	R	47.7	Very low	64.3	Low	196 Å²	196	101.5 Å²	101.5	74%	0.74	61%	0.611	S	S	*	*			trans	-56.2	116.6	169.5	-74.9	-177.6	-167.8	161	3.6	108.3	P139 I143	P139-R141 PolarHBondContact O-N 3.49Å; R141-I143 HydrophobicContact CB-CG1 4.33Å; R141-I143 PolarHBondContact O-N 3.04Å; R141-I143 VanDerWaalsContact O-N 3.14Å
142	V	52.6	Low	66.7	Low	119 Å²	119	96.3 Å²	96.3	72%	0.721	58%	0.577	S	S	*	*			trans	-79	94	166.1	-171.9	0	0	0	0	106.4	K140 V144	K140-V142 PolarHBondContact O-N 3.38Å; K140-V142 VanDerWaalsContact O-N 3.1Å; V142-V144 HydrophobicContact CG1-CG2 3.97Å; V142-V144 PolarHBondContact O-N 2.91Å; V142-V144 VanDerWaalsContact O-N 3.11Å
143	I	54	Low	69.2	Low	133 Å²	133	98.1 Å²	98.1	68%	0.682	56%	0.563	S	S	*	*			trans	-77.5	94.5	170.4	-59.1	174.7	0	0	0	106.2	R141 Q145	R141-I143 HydrophobicContact CB-CG1 4.33Å; R141-I143 PolarHBondContact O-N 3.04Å; R141-I143 VanDerWaalsContact O-N 3.14Å; I143-Q145 HydrophobicContact CG2-CB 4.42Å; I143-Q145 PolarHBondContact O-N 3.2Å; I143-Q145 VanDerWaalsContact O-N 3.14Å
144	V	61.4	Low	71.5	Confident	51 Å²	51	91.7 Å²	91.7	31%	0.309	52%	0.524	S	S	.	.			trans	-81.2	94.3	172.8	-134.1	0	0	0	0	108.4	L95 V142 F286 K290	L95-V144 HydrophobicContact CD2-CG2 4.31Å; V142-V144 HydrophobicContact CG1-CG2 3.97Å; V142-V144 PolarHBondContact O-N 2.91Å; V142-V144 VanDerWaalsContact O-N 3.11Å; V144-F286 HydrophobicContact CB-CD1 4.22Å; V144-F286 HydrophobicContact CB-CE1 3.66Å; V144-F286 HydrophobicContact CB-CZ 4.33Å; V144-F286 HydrophobicContact CG1-CD1 3.85Å; V144-F286 HydrophobicContact CG1-CE1 3.27Å; V144-F286 HydrophobicContact CG1-CZ 4.24Å; V144-K290 HydrophobicContact CG1-CD 4.42Å
145	Q	79.9	Confident	73.8	Confident	155 Å²	155	85.7 Å²	85.7	72%	0.724	49%	0.487	S	S	*	.			trans	-98.4	134	175.2	-169	175.9	-42.7	0	0	109.5	I143 K290	I143-Q145 HydrophobicContact CG2-CB 4.42Å; I143-Q145 PolarHBondContact O-N 3.2Å; I143-Q145 VanDerWaalsContact O-N 3.14Å; Q145-K290 PolarHBondContact O-NZ 3.48Å
146	A	84.5	Confident	76.2	Confident	16 Å²	16	80 Å²	80	13%	0.132	45%	0.447	C	S	.	.			trans	-148.4	144.1	163.8	0	0	0	0	0	108.1	E150 L151 F286 K290	A146-E150 WeakPolarHBondContact CA-OE2 3.38Å; A146-L151 HydrophobicContact CB-CD1 4.25Å; A146-L151 HydrophobicContact CB-CD2 3.71Å; A146-L151 HydrophobicContact CB-CG 3.84Å; A146-F286 HydrophobicContact CB-CE2 4.29Å; A146-F286 HydrophobicContact CB-CZ 3.74Å; A146-K290 HydrophobicContact CB-CD 4.07Å; A146-K290 HydrophobicContact CB-CG 4.43Å
147	S	94.4	Very high	78.5	Confident	62 Å²	62	75.3 Å²	75.3	43%	0.434	41%	0.408	S	S	.	.			trans	-78.5	154.8	174.9	72.9	0	0	0	0	110.8	S149 E150 L151	S147-S149 PolarHBondContact O-N 3.31Å; S147-E150 PolarHBondContact N-OE2 3.37Å; S147-E150 WeakPolarHBondContact O-CB 3.16Å; S147-E150 PolarHBondContact O-N 3.04Å; S147-E150 VanDerWaalsContact O-N 3.17Å; S147-E150 VanDerWaalsContact OG-CB 3.25Å; S147-E150 WeakPolarHBondContact OG-CB 3.49Å; S147-E150 PolarHBondContact OG-N 3.09Å; S147-E150 VanDerWaalsContact OG-N 3.09Å; S147-L151 WeakPolarHBondContact O-CG 3.3Å; S147-L151 PolarHBondContact O-N 2.58Å
148	T	96.9	Very high	80.9	Confident	30 Å²	30	72.2 Å²	72.2	18%	0.184	37%	0.374	C	S	.	.	H	α-helix	trans	-55.9	-39.3	173.6	-49.2	0	0	0	0	111.9	L151 L152 I196 P198 V201	T148-L151 PolarHBondContact O-N 3.41Å; T148-L152 HydrophobicContact CG2-CD1 4.16Å; T148-L152 WeakPolarHBondContact O-CB 3.45Å; T148-L152 VanDerWaalsContact O-CG 3.28Å; T148-L152 WeakPolarHBondContact O-CG 3.37Å; T148-L152 PolarHBondContact O-N 2.99Å; T148-I196 HydrophobicContact CG2-CG2 3.66Å; T148-I196 WeakPolarHBondContact CG2-O 3.29Å; T148-P198 WeakPolarHBondContact OG1-CD 3.27Å; T148-V201 HydrophobicContact CG2-CG2 4.24Å
149	S	96.8	Very high	83.1	Confident	78 Å²	78	66.3 Å²	66.3	55%	0.545	34%	0.338	S	S	.	.	H	α-helix	trans	-66.6	-38.1	179.7	-58.3	0	0	0	0	112.4	S147 R153	S147-S149 PolarHBondContact O-N 3.31Å; S149-R153 WeakPolarHBondContact O-CB 3.45Å; S149-R153 PolarHBondContact O-N 3.01Å
150	E	96.3	Very high	85.3	Confident	80 Å²	80	61.7 Å²	61.7	37%	0.374	31%	0.308	S	S	.	.	H	α-helix	trans	-64.6	-47.2	174.6	-177.9	-175.5	176.4	0	0	111	A146 S147 L152 R153 C154	A146-E150 WeakPolarHBondContact CA-OE2 3.38Å; S147-E150 PolarHBondContact N-OE2 3.37Å; S147-E150 WeakPolarHBondContact O-CB 3.16Å; S147-E150 PolarHBondContact O-N 3.04Å; S147-E150 VanDerWaalsContact O-N 3.17Å; S147-E150 VanDerWaalsContact OG-CB 3.25Å; S147-E150 WeakPolarHBondContact OG-CB 3.49Å; S147-E150 PolarHBondContact OG-N 3.09Å; S147-E150 VanDerWaalsContact OG-N 3.09Å; E150-L152 VanDerWaalsContact C-N 3.35Å; E150-L152 PolarHBondContact O-N 2.93Å; E150-R153 WeakPolarHBondContact O-CB 3.41Å; E150-R153 PolarHBondContact O-N 2.89Å; E150-R153 VanDerWaalsContact O-N 3.13Å; E150-C154 PolarHBondContact O-N 3.37Å; E150-C154 PolarHBondContact O-SG 3.38Å; E150-C154 VanDerWaalsContact O-SG 3.34Å
151	L	97.9	Very high	87.7	Confident	0 Å²	0	55.2 Å²	55.2	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-64.4	-38	178.4	-65.1	176	0	0	0	112.8	A146 S147 T148 R153 C154 L155 P198 V201 V202 F286 L289 K290	A146-L151 HydrophobicContact CB-CD1 4.25Å; A146-L151 HydrophobicContact CB-CD2 3.71Å; A146-L151 HydrophobicContact CB-CG 3.84Å; S147-L151 WeakPolarHBondContact O-CG 3.3Å; S147-L151 PolarHBondContact O-N 2.58Å; T148-L151 PolarHBondContact O-N 3.41Å; L151-R153 VanDerWaalsContact C-N 3.32Å; L151-C154 PolarHBondContact O-N 2.81Å; L151-L155 WeakPolarHBondContact O-CB 3.39Å; L151-L155 PolarHBondContact O-N 2.87Å; L151-P198 HydrophobicContact CD1-CB 3.69Å; L151-V201 HydrophobicContact CB-CB 4.35Å; L151-V201 HydrophobicContact CB-CG1 3.81Å; L151-V202 HydrophobicContact CD1-CG2 4.48Å; L151-F286 HydrophobicContact CD1-CE2 4.02Å; L151-F286 HydrophobicContact CD2-CE2 4.23Å; L151-L289 HydrophobicContact CB-CD2 4.13Å; L151-L289 HydrophobicContact CD2-CD2 3.93Å; L151-L289 HydrophobicContact CD2-CG 4.14Å; L151-K290 HydrophobicContact CD2-CG 4.03Å
152	L	98.4	Very high	90.1	Very high	1 Å²	1	49.2 Å²	49.2	1%	0.005	26%	0.256	C	S	.	.	H	α-helix	trans	-63.3	-39.8	173.2	-76.7	169.2	0	0	0	111.7	T148 E150 L155 G156 V175 L178 R179 I196 V201	T148-L152 HydrophobicContact CG2-CD1 4.16Å; T148-L152 WeakPolarHBondContact O-CB 3.45Å; T148-L152 VanDerWaalsContact O-CG 3.28Å; T148-L152 WeakPolarHBondContact O-CG 3.37Å; T148-L152 PolarHBondContact O-N 2.99Å; E150-L152 VanDerWaalsContact C-N 3.35Å; E150-L152 PolarHBondContact O-N 2.93Å; L152-L155 PolarHBondContact O-N 3.38Å; L152-G156 PolarHBondContact O-N 3.18Å; L152-V175 HydrophobicContact CB-CG1 4.09Å; L152-V175 HydrophobicContact CB-CG2 4.03Å; L152-V175 HydrophobicContact CD1-CG1 4.2Å; L152-V175 WeakPolarHBondContact O-CG2 3.48Å; L152-L178 HydrophobicContact CD2-CD1 3.72Å; L152-R179 HydrophobicContact CD1-CG 4.43Å; L152-R179 VanDerWaalsContact CD1-NE 3.32Å; L152-I196 HydrophobicContact CD1-CG2 3.77Å; L152-I196 HydrophobicContact CD2-CG2 4.14Å; L152-I196 HydrophobicContact CG-CG2 4.28Å; L152-V201 HydrophobicContact CD2-CG1 4.32Å; L152-V201 HydrophobicContact CD2-CG2 3.88Å; L152-V201 HydrophobicContact CG-CG2 4.08Å
153	R	97.6	Very high	92.3	Very high	137 Å²	137	43.5 Å²	43.5	52%	0.517	22%	0.221	S	C	.	.	H	α-helix	trans	-64	-46.1	174.8	-178.7	-178.3	168.9	-153	-10.8	111.1	S149 E150 L151 L155 G156 E157	S149-R153 WeakPolarHBondContact O-CB 3.45Å; S149-R153 PolarHBondContact O-N 3.01Å; E150-R153 WeakPolarHBondContact O-CB 3.41Å; E150-R153 PolarHBondContact O-N 2.89Å; E150-R153 VanDerWaalsContact O-N 3.13Å; L151-R153 VanDerWaalsContact C-N 3.32Å; R153-L155 VanDerWaalsContact C-N 3.29Å; R153-L155 PolarHBondContact O-N 3.28Å; R153-G156 WeakPolarHBondContact O-CA 3.16Å; R153-G156 PolarHBondContact O-N 3.49Å; R153-G156 VanDerWaalsContact O-N 3.09Å; R153-E157 IonicContact CZ-OE1 3.18Å; R153-E157 IonicContact NE-OE1 2.79Å; R153-E157 PolarHBondContact NE-OE1 3Å; R153-E157 IonicContact NH2-OE1 2.82Å; R153-E157 PolarHBondContact NH2-OE1 2.79Å; R153-E157 PolarHBondContact O-N 3.47Å
154	C	97.8	Very high	94.3	Very high	2 Å²	2	42.5 Å²	42.5	1%	0.014	21%	0.209	C	C	.	.	H	α-helix	trans	-56.8	-43.1	174.5	-67.3	0	0	0	0	112	E150 L151 G156 E157 F158 L289 E292	E150-C154 PolarHBondContact O-N 3.37Å; E150-C154 PolarHBondContact O-SG 3.38Å; E150-C154 VanDerWaalsContact O-SG 3.34Å; L151-C154 PolarHBondContact O-N 2.81Å; C154-G156 VanDerWaalsContact C-N 3.35Å; C154-E157 PolarHBondContact O-N 2.86Å; C154-F158 WeakPolarHBondContact O-CB 3.49Å; C154-F158 PolarHBondContact O-N 3.33Å; C154-L289 HydrophobicContact CB-CD1 3.74Å; C154-L289 HydrophobicContact CB-CG 4.2Å; C154-L289 WeakPolarHBondContact CB-O 3.35Å; C154-E292 HydrophobicContact CB-CB 4.27Å
155	L	98.5	Very high	96.1	Very high	0 Å²	0	46.3 Å²	46.3	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-62	-42.7	175.2	178	62.9	0	0	0	111.3	L151 L152 R153 F158 L159 L178 V201 L204 Y205 C208 L289	L151-L155 WeakPolarHBondContact O-CB 3.39Å; L151-L155 PolarHBondContact O-N 2.87Å; L152-L155 PolarHBondContact O-N 3.38Å; R153-L155 VanDerWaalsContact C-N 3.29Å; R153-L155 PolarHBondContact O-N 3.28Å; L155-F158 HydrophobicContact CD1-CD1 4.02Å; L155-F158 WeakPolarHBondContact O-CB 3.5Å; L155-F158 PolarHBondContact O-N 3.03Å; L155-L159 HydrophobicContact CD1-CD1 4.47Å; L155-L159 HydrophobicContact CD1-CG 4.43Å; L155-L159 HydrophobicContact CG-CD1 4.31Å; L155-L159 VanDerWaalsContact O-CG 3.26Å; L155-L159 WeakPolarHBondContact O-CG 3.3Å; L155-L159 PolarHBondContact O-N 3.44Å; L155-L178 HydrophobicContact CD2-CD1 3.83Å; L155-V201 HydrophobicContact CD2-CG1 4.44Å; L155-L204 HydrophobicContact CD2-CD2 3.8Å; L155-L204 HydrophobicContact CD2-CG 4.21Å; L155-Y205 HydrophobicContact CD1-CD2 4Å; L155-C208 HydrophobicContact CD1-CB 4.31Å; L155-L289 HydrophobicContact CB-CD1 4.19Å
156	G	98.3	Very high	96.9	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-60.6	-45.1	175.3	0	0	0	0	0	113.3	L152 R153 C154 L159 C160 P171	L152-G156 PolarHBondContact O-N 3.18Å; R153-G156 WeakPolarHBondContact O-CA 3.16Å; R153-G156 PolarHBondContact O-N 3.49Å; R153-G156 VanDerWaalsContact O-N 3.09Å; C154-G156 VanDerWaalsContact C-N 3.35Å; G156-L159 PolarHBondContact O-N 3.27Å; G156-C160 PolarHBondContact O-N 3.43Å; G156-C160 PolarHBondContact O-SG 2.89Å; G156-P171 WeakPolarHBondContact CA-O 3.24Å
157	E	97.7	Very high	97.5	Very high	3 Å²	3	46.4 Å²	46.4	1%	0.014	21%	0.214	C	C	.	.	H	α-helix	trans	-65.8	-40.1	176.8	-71.2	171.6	-178.1	0	0	111.9	R153 C154 L159 C160 R161 P171 S293	R153-E157 IonicContact CZ-OE1 3.18Å; R153-E157 IonicContact NE-OE1 2.79Å; R153-E157 PolarHBondContact NE-OE1 3Å; R153-E157 IonicContact NH2-OE1 2.82Å; R153-E157 PolarHBondContact NH2-OE1 2.79Å; R153-E157 PolarHBondContact O-N 3.47Å; C154-E157 PolarHBondContact O-N 2.86Å; E157-L159 PolarHBondContact O-N 3.35Å; E157-C160 PolarHBondContact O-N 2.98Å; E157-R161 PolarHBondContact O-N 3.27Å; E157-P171 HydrophobicContact CG-CB 3.88Å; E157-S293 WeakPolarHBondContact OE2-CA 3.36Å; E157-S293 VanDerWaalsContact OE2-CB 3.3Å; E157-S293 WeakPolarHBondContact OE2-CB 3.5Å
158	F	98.4	Very high	97.5	Very high	7 Å²	7	51.6 Å²	51.6	3%	0.031	23%	0.231	C	C	.	.	H	α-helix	trans	-55.7	-49.4	170.9	160.7	-100.6	0	0	0	111.7	C154 L155 C160 R161 R162 Y205 C208 R209 E292	C154-F158 WeakPolarHBondContact O-CB 3.49Å; C154-F158 PolarHBondContact O-N 3.33Å; L155-F158 HydrophobicContact CD1-CD1 4.02Å; L155-F158 WeakPolarHBondContact O-CB 3.5Å; L155-F158 PolarHBondContact O-N 3.03Å; F158-C160 PolarHBondContact O-N 3.34Å; F158-R161 PolarHBondContact O-N 3.15Å; F158-R162 HydrophobicContact CE2-CB 4.3Å; F158-R162 HydrophobicContact CZ-CB 4.16Å; F158-R162 HydrophobicContact CZ-CG 4.31Å; F158-R162 VanDerWaalsContact CZ-CZ 3.47Å; F158-R162 WeakPolarHBondContact O-CB 3.37Å; F158-R162 PolarHBondContact O-N 2.72Å; F158-Y205 HydrophobicContact CB-CE2 4.47Å; F158-Y205 HydrophobicContact CD1-CD2 4.09Å; F158-Y205 HydrophobicContact CD1-CE2 4.05Å; F158-Y205 AromaticContact CD2-CE2 3.87Å; F158-Y205 HydrophobicContact CD2-CE2 3.87Å; F158-Y205 HydrophobicContact CE1-CD2 4.43Å; F158-Y205 HydrophobicContact CE1-CE2 4.35Å; F158-Y205 HydrophobicContact CE2-CE2 4.17Å; F158-Y205 HydrophobicContact CG-CD2 4.26Å; F158-Y205 AromaticContact CG-CE2 3.83Å; F158-Y205 HydrophobicContact CG-CE2 3.83Å; F158-Y205 HydrophobicContact CZ-CE2 4.44Å; F158-C208 HydrophobicContact CE1-CB 4.05Å; F158-R209 HydrophobicContact CE2-CB 4.33Å; F158-R209 HydrophobicContact CZ-CB 4.01Å; F158-E292 HydrophobicContact CB-CB 4.13Å; F158-E292 HydrophobicContact CB-CG 3.84Å; F158-E292 HydrophobicContact CD2-CG 4.4Å; F158-E292 HydrophobicContact CG-CG 4.44Å
159	L	98.4	Very high	97.6	Very high	0 Å²	0	50.9 Å²	50.9	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-64.6	-41.4	-178.6	-67.9	172.1	0	0	0	111.8	L155 G156 E157 R161 R162 C163 P174 C208 I212 L222 L226	L155-L159 HydrophobicContact CD1-CD1 4.47Å; L155-L159 HydrophobicContact CD1-CG 4.43Å; L155-L159 HydrophobicContact CG-CD1 4.31Å; L155-L159 VanDerWaalsContact O-CG 3.26Å; L155-L159 WeakPolarHBondContact O-CG 3.3Å; L155-L159 PolarHBondContact O-N 3.44Å; G156-L159 PolarHBondContact O-N 3.27Å; E157-L159 PolarHBondContact O-N 3.35Å; L159-R161 VanDerWaalsContact C-N 3.29Å; L159-R161 PolarHBondContact O-N 2.75Å; L159-R162 PolarHBondContact O-N 3.28Å; L159-C163 WeakPolarHBondContact O-CB 3.43Å; L159-C163 PolarHBondContact O-N 3.4Å; L159-P174 HydrophobicContact CB-CG 4.36Å; L159-P174 HydrophobicContact CD1-CB 3.59Å; L159-P174 HydrophobicContact CD1-CG 3.68Å; L159-C208 HydrophobicContact CD2-CB 4.46Å; L159-I212 HydrophobicContact CD2-CD1 3.42Å; L159-I212 VanDerWaalsContact CD2-CD1 3.42Å; L159-I212 HydrophobicContact CD2-CG2 4.39Å; L159-L222 HydrophobicContact CD2-CD1 4.28Å; L159-L226 HydrophobicContact CD1-CD1 4.18Å; L159-L226 HydrophobicContact CD1-CD2 4Å
160	C	97.4	Very high	97.6	Very high	27 Å²	27	49.2 Å²	49.2	18%	0.182	22%	0.215	C	C	.	.	H	α-helix	trans	-60.3	-39.8	174.9	-65.3	0	0	0	0	112.1	G156 E157 F158 P171	G156-C160 PolarHBondContact O-N 3.43Å; G156-C160 PolarHBondContact O-SG 2.89Å; E157-C160 PolarHBondContact O-N 2.98Å; F158-C160 PolarHBondContact O-N 3.34Å; C160-P171 VanDerWaalsContact SG-CA 3.54Å; C160-P171 VanDerWaalsContact SG-N 3.42Å
161	R	97.1	Very high	97.6	Very high	62 Å²	62	47.5 Å²	47.5	23%	0.234	21%	0.21	C	C	.	.	H	α-helix	trans	-73.2	-40.2	178.4	-162.8	178.7	-46.8	103.9	7.3	112.6	E157 F158 L159 E292	E157-R161 PolarHBondContact O-N 3.27Å; F158-R161 PolarHBondContact O-N 3.15Å; L159-R161 VanDerWaalsContact C-N 3.29Å; L159-R161 PolarHBondContact O-N 2.75Å; R161-E292 IonicContact CZ-OE2 3.71Å; R161-E292 IonicContact NH1-OE2 2.72Å; R161-E292 PolarHBondContact NH1-OE2 2.97Å; R161-E292 PolarHBondContact NH2-O 2.87Å
162	R	97.8	Very high	97.6	Very high	70 Å²	70	51.6 Å²	51.6	26%	0.264	24%	0.235	S	C	.	.	H	α-helix	trans	-63.2	-52	178.2	177	62.3	67	84.5	-6	110.6	F158 L159 Y164 R209 I212 S214	F158-R162 HydrophobicContact CE2-CB 4.3Å; F158-R162 HydrophobicContact CZ-CB 4.16Å; F158-R162 HydrophobicContact CZ-CG 4.31Å; F158-R162 VanDerWaalsContact CZ-CZ 3.47Å; F158-R162 WeakPolarHBondContact O-CB 3.37Å; F158-R162 PolarHBondContact O-N 2.72Å; L159-R162 PolarHBondContact O-N 3.28Å; R162-Y164 VanDerWaalsContact C-N 3.27Å; R162-Y164 PolarHBondContact O-N 3.28Å; R162-R209 VanDerWaalsContact CZ-O 3.28Å; R162-R209 PolarHBondContact NH1-O 3.02Å; R162-R209 PolarHBondContact NH2-O 3.42Å; R162-I212 HydrophobicContact CG-CG2 4.36Å; R162-I212 PolarHBondContact NH1-O 3.43Å; R162-S214 VanDerWaalsContact O-CA 3.29Å; R162-S214 WeakPolarHBondContact O-CA 3.32Å
163	C	98.2	Very high	97.6	Very high	0 Å²	0	53.6 Å²	53.6	0%	0	25%	0.246	C	C	.	.			trans	-88	62.2	-175.4	-57.2	0	0	0	0	111	L159 R165 L166	L159-C163 WeakPolarHBondContact O-CB 3.43Å; L159-C163 PolarHBondContact O-N 3.4Å; C163-R165 PolarHBondContact O-N 3.48Å; C163-L166 HydrophobicContact CB-CD1 3.66Å; C163-L166 HydrophobicContact CB-CG 3.91Å; C163-L166 WeakPolarHBondContact O-CB 3.25Å; C163-L166 PolarHBondContact O-N 3.24Å
164	Y	97.2	Very high	97.7	Very high	111 Å²	111	47.1 Å²	47.1	44%	0.435	22%	0.222	S	C	.	.	T	Hydrogen-bonded Turn	trans	-58.5	-17.1	-172.2	70.8	-86.7	0	0	0	115	R162 K167 S214 E215	R162-Y164 VanDerWaalsContact C-N 3.27Å; R162-Y164 PolarHBondContact O-N 3.28Å; Y164-K167 WeakPolarHBondContact O-CE 3.17Å; Y164-K167 PolarHBondContact O-NZ 3.43Å; Y164-S214 VanDerWaalsContact CD1-O 3.3Å; Y164-S214 WeakPolarHBondContact CD1-O 3.21Å; Y164-S214 WeakPolarHBondContact CE1-O 3.26Å; Y164-E215 VanDerWaalsContact CE1-OE1 3.27Å; Y164-E215 WeakPolarHBondContact CE1-OE1 3.34Å; Y164-E215 VanDerWaalsContact OH-CD 3.24Å; Y164-E215 PolarHBondContact OH-OE1 3.24Å; Y164-E215 PolarHBondContact OH-OE2 2.99Å
165	R	98.1	Very high	97.7	Very high	131 Å²	131	48.7 Å²	48.7	49%	0.494	23%	0.231	S	C	.	.	T	Hydrogen-bonded Turn	trans	-75.2	-23	176.6	-61.5	179.3	67.8	-174.7	4.1	112.7	C163 K167 E215	C163-R165 PolarHBondContact O-N 3.48Å; R165-K167 PolarHBondContact O-N 3.44Å; R165-K167 VanDerWaalsContact O-N 3.14Å; R165-E215 PolarHBondContact NH1-O 3.04Å
166	L	97.8	Very high	97.7	Very high	16 Å²	16	54.1 Å²	54.1	8%	0.084	26%	0.26	C	S	.	.			trans	-86.1	82.3	-175.3	-52.8	-174.6	0	0	0	111.1	C163 H168 L169 V216 S218 L222	C163-L166 HydrophobicContact CB-CD1 3.66Å; C163-L166 HydrophobicContact CB-CG 3.91Å; C163-L166 WeakPolarHBondContact O-CB 3.25Å; C163-L166 PolarHBondContact O-N 3.24Å; L166-H168 PolarHBondContact O-N 3.13Å; L166-L169 HydrophobicContact CB-CB 3.84Å; L166-L169 HydrophobicContact CB-CD2 4.42Å; L166-L169 HydrophobicContact CD1-CD2 4.04Å; L166-L169 PolarHBondContact O-N 2.9Å; L166-V216 HydrophobicContact CD1-CG1 4.27Å; L166-S218 VanDerWaalsContact CD2-CA 3.42Å; L166-L222 HydrophobicContact CD1-CB 3.91Å; L166-L222 HydrophobicContact CD1-CD2 3.74Å; L166-L222 HydrophobicContact CD1-CG 4.43Å
167	K	95.6	Very high	97.7	Very high	157 Å²	157	56 Å²	56	68%	0.683	27%	0.267	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.6	-16.4	-172.5	-55.8	-52.1	-175.1	-173.8	0	115	Y164 R165	Y164-K167 WeakPolarHBondContact O-CE 3.17Å; Y164-K167 PolarHBondContact O-NZ 3.43Å; R165-K167 PolarHBondContact O-N 3.44Å; R165-K167 VanDerWaalsContact O-N 3.14Å
168	H	95.9	Very high	97.8	Very high	171 Å²	171	55.9 Å²	55.9	79%	0.792	27%	0.266	S	S	*	.	T	Hydrogen-bonded Turn	trans	-112.8	1.3	-176.3	-59.4	-57.4	0	0	0	113.4	L166 S170	L166-H168 PolarHBondContact O-N 3.13Å; H168-S170 PolarHBondContact O-N 3.34Å
169	L	97.6	Very high	97.8	Very high	16 Å²	16	60.1 Å²	60.1	8%	0.084	28%	0.282	C	S	.	.			trans	-67.8	121.9	177.2	-177.4	71.4	0	0	0	109.7	L166 D173 W177 L222	L166-L169 HydrophobicContact CB-CB 3.84Å; L166-L169 HydrophobicContact CB-CD2 4.42Å; L166-L169 HydrophobicContact CD1-CD2 4.04Å; L166-L169 PolarHBondContact O-N 2.9Å; L169-D173 HydrophobicContact CD1-CB 4.08Å; L169-W177 HydrophobicContact CD1-CH2 3.83Å; L169-L222 HydrophobicContact CD1-CD2 3.98Å; L169-L222 HydrophobicContact CD2-CD2 3.33Å; L169-L222 HydrophobicContact CG-CD2 4.32Å
170	S	97.1	Very high	97.8	Very high	43 Å²	43	63.7 Å²	63.7	30%	0.301	31%	0.307	S	S	.	.			trans	-86.4	142.6	170.9	178.2	0	0	0	0	110.1	H168 T172 D173 P174	H168-S170 PolarHBondContact O-N 3.34Å; S170-T172 PolarHBondContact O-N 2.95Å; S170-T172 PolarHBondContact OG-N 3.09Å; S170-T172 PolarHBondContact OG-OG1 3.17Å; S170-D173 WeakPolarHBondContact CB-OD2 3.34Å; S170-D173 PolarHBondContact N-OD2 3.39Å; S170-D173 PolarHBondContact O-N 3.25Å; S170-P174 VanDerWaalsContact O-CD 3.28Å; S170-P174 WeakPolarHBondContact O-CD 3.34Å
171	P	97	Very high	97.9	Very high	43 Å²	43	62.7 Å²	62.7	28%	0.279	30%	0.3	S	S	.	.	T	Hydrogen-bonded Turn	trans	-60.4	-14.3	172.2	25.3	-34.7	0	0	0	112.9	G156 E157 C160	G156-P171 WeakPolarHBondContact CA-O 3.24Å; E157-P171 HydrophobicContact CG-CB 3.88Å; C160-P171 VanDerWaalsContact SG-CA 3.54Å; C160-P171 VanDerWaalsContact SG-N 3.42Å
172	T	98	Very high	97.9	Very high	86 Å²	86	60.4 Å²	60.4	53%	0.528	29%	0.292	S	S	.	.	H	α-helix	trans	-80.9	-21.3	173.4	59.1	0	0	0	0	114.1	S170 V175 L176	S170-T172 PolarHBondContact O-N 2.95Å; S170-T172 PolarHBondContact OG-N 3.09Å; S170-T172 PolarHBondContact OG-OG1 3.17Å; T172-V175 WeakPolarHBondContact O-CB 3.37Å; T172-V175 PolarHBondContact O-N 3.27Å; T172-L176 PolarHBondContact O-N 3.26Å
173	D	98.4	Very high	97.9	Very high	43 Å²	43	65.3 Å²	65.3	23%	0.23	31%	0.311	C	S	.	.	H	α-helix	trans	-67.1	-47.2	-174	-58.4	-30.9	0	0	0	111.8	L169 S170 V175 L176 W177	L169-D173 HydrophobicContact CD1-CB 4.08Å; S170-D173 WeakPolarHBondContact CB-OD2 3.34Å; S170-D173 PolarHBondContact N-OD2 3.39Å; S170-D173 PolarHBondContact O-N 3.25Å; D173-V175 VanDerWaalsContact C-N 3.27Å; D173-V175 PolarHBondContact O-N 3.41Å; D173-L176 WeakPolarHBondContact O-CB 3.25Å; D173-L176 PolarHBondContact O-N 3.11Å; D173-L176 VanDerWaalsContact O-N 3.13Å; D173-W177 HydrophobicContact CB-CH2 4.25Å; D173-W177 HydrophobicContact CB-CZ2 3.8Å; D173-W177 VanDerWaalsContact O-CD2 3.32Å; D173-W177 PolarHBondContact O-N 3.06Å
174	P	98.6	Very high	97.9	Very high	1 Å²	1	67 Å²	67	1%	0.006	32%	0.323	C	S	.	.	H	α-helix	trans	-56.7	-42	171.9	-26.2	36.7	0	0	0	112.4	L159 S170 L176 W177 L178 L226	L159-P174 HydrophobicContact CB-CG 4.36Å; L159-P174 HydrophobicContact CD1-CB 3.59Å; L159-P174 HydrophobicContact CD1-CG 3.68Å; S170-P174 VanDerWaalsContact O-CD 3.28Å; S170-P174 WeakPolarHBondContact O-CD 3.34Å; P174-L176 VanDerWaalsContact C-N 3.3Å; P174-L176 PolarHBondContact O-N 2.93Å; P174-W177 HydrophobicContact CB-CE3 4.45Å; P174-W177 HydrophobicContact CG-CZ3 4.31Å; P174-W177 PolarHBondContact O-N 3.23Å; P174-L178 WeakPolarHBondContact O-CG 3.22Å; P174-L178 PolarHBondContact O-N 3.05Å; P174-L226 HydrophobicContact CB-CD2 3.89Å
175	V	98.6	Very high	98	Very high	36 Å²	36	61.8 Å²	61.8	22%	0.218	30%	0.302	C	S	.	.	H	α-helix	trans	-60.4	-42.8	178.7	-176.6	0	0	0	0	111	L152 T172 D173 R179	L152-V175 HydrophobicContact CB-CG1 4.09Å; L152-V175 HydrophobicContact CB-CG2 4.03Å; L152-V175 HydrophobicContact CD1-CG1 4.2Å; L152-V175 WeakPolarHBondContact O-CG2 3.48Å; T172-V175 WeakPolarHBondContact O-CB 3.37Å; T172-V175 PolarHBondContact O-N 3.27Å; D173-V175 VanDerWaalsContact C-N 3.27Å; D173-V175 PolarHBondContact O-N 3.41Å; V175-R179 HydrophobicContact CG1-CG 4.31Å; V175-R179 VanDerWaalsContact O-CB 3.32Å; V175-R179 WeakPolarHBondContact O-CB 3.47Å; V175-R179 VanDerWaalsContact O-CG 3.25Å; V175-R179 WeakPolarHBondContact O-CG 3.28Å; V175-R179 PolarHBondContact O-N 2.97Å
176	L	98.6	Very high	98	Very high	114 Å²	114	59.3 Å²	59.3	60%	0.597	30%	0.299	S	S	*	.	H	α-helix	trans	-64.9	-44.8	178.3	-177.7	62.6	0	0	0	111.6	T172 D173 P174 R179 S180	T172-L176 PolarHBondContact O-N 3.26Å; D173-L176 WeakPolarHBondContact O-CB 3.25Å; D173-L176 PolarHBondContact O-N 3.11Å; D173-L176 VanDerWaalsContact O-N 3.13Å; P174-L176 VanDerWaalsContact C-N 3.3Å; P174-L176 PolarHBondContact O-N 2.93Å; L176-R179 PolarHBondContact O-N 3.13Å; L176-S180 WeakPolarHBondContact O-CB 3.3Å; L176-S180 PolarHBondContact O-N 3.26Å
177	W	98.8	Very high	98	Very high	38 Å²	38	63.7 Å²	63.7	14%	0.144	32%	0.322	C	S	.	.	H	α-helix	trans	-60.5	-48.4	178.2	-56.3	-26.1	0	0	0	111.5	L169 D173 P174 S180 V181 L222 Q223 L226	L169-W177 HydrophobicContact CD1-CH2 3.83Å; D173-W177 HydrophobicContact CB-CH2 4.25Å; D173-W177 HydrophobicContact CB-CZ2 3.8Å; D173-W177 VanDerWaalsContact O-CD2 3.32Å; D173-W177 PolarHBondContact O-N 3.06Å; P174-W177 HydrophobicContact CB-CE3 4.45Å; P174-W177 HydrophobicContact CG-CZ3 4.31Å; P174-W177 PolarHBondContact O-N 3.23Å; W177-S180 PolarHBondContact O-N 3.34Å; W177-V181 PolarHBondContact O-N 2.89Å; W177-L222 HydrophobicContact CH2-CD2 4.48Å; W177-L222 HydrophobicContact CZ3-CD2 4.24Å; W177-L222 HydrophobicContact CZ3-CG 4.15Å; W177-Q223 HydrophobicContact CD2-CB 4.12Å; W177-Q223 HydrophobicContact CD2-CG 3.72Å; W177-Q223 HydrophobicContact CE3-CB 3.87Å; W177-Q223 HydrophobicContact CE3-CG 3.84Å; W177-Q223 HydrophobicContact CG-CG 4.06Å; W177-Q223 HydrophobicContact CH2-CB 4.01Å; W177-Q223 HydrophobicContact CZ2-CB 4.23Å; W177-Q223 HydrophobicContact CZ3-CB 3.82Å; W177-Q223 HydrophobicContact CZ3-CG 4.32Å; W177-L226 HydrophobicContact CE3-CD2 4Å
178	L	98.8	Very high	98	Very high	1 Å²	1	61.5 Å²	61.5	1%	0.005	31%	0.314	C	S	.	.	H	α-helix	trans	-62.1	-48.1	179.3	-63.4	178.5	0	0	0	111.8	L152 L155 P174 S180 V181 D182 I196 L204 L226 L230	L152-L178 HydrophobicContact CD2-CD1 3.72Å; L155-L178 HydrophobicContact CD2-CD1 3.83Å; P174-L178 WeakPolarHBondContact O-CG 3.22Å; P174-L178 PolarHBondContact O-N 3.05Å; L178-S180 VanDerWaalsContact C-N 3.31Å; L178-S180 PolarHBondContact O-N 3.14Å; L178-V181 PolarHBondContact O-N 3.46Å; L178-D182 PolarHBondContact O-N 2.98Å; L178-D182 VanDerWaalsContact O-N 3.12Å; L178-I196 HydrophobicContact CB-CD1 4.47Å; L178-L204 HydrophobicContact CD1-CD2 3.7Å; L178-L204 HydrophobicContact CD2-CD2 3.8Å; L178-L204 HydrophobicContact CG-CD2 4.41Å; L178-L226 HydrophobicContact CD2-CD1 4.39Å; L178-L226 HydrophobicContact CD2-CD2 4.11Å; L178-L226 HydrophobicContact CD2-CG 4.11Å; L178-L226 HydrophobicContact CG-CD2 4.32Å; L178-L230 HydrophobicContact CD2-CB 4.22Å; L178-L230 HydrophobicContact CD2-CD1 3.89Å; L178-L230 HydrophobicContact CD2-CD2 3.65Å; L178-L230 HydrophobicContact CD2-CG 4.09Å
179	R	98.5	Very high	98.1	Very high	97 Å²	97	56.5 Å²	56.5	37%	0.366	31%	0.309	S	S	.	.	H	α-helix	trans	-66.4	-32.9	179	-72.2	-67.9	-167.4	165.3	3.6	112.6	L152 V175 L176 R183	L152-R179 HydrophobicContact CD1-CG 4.43Å; L152-R179 VanDerWaalsContact CD1-NE 3.32Å; V175-R179 HydrophobicContact CG1-CG 4.31Å; V175-R179 VanDerWaalsContact O-CB 3.32Å; V175-R179 WeakPolarHBondContact O-CB 3.47Å; V175-R179 VanDerWaalsContact O-CG 3.25Å; V175-R179 WeakPolarHBondContact O-CG 3.28Å; V175-R179 PolarHBondContact O-N 2.97Å; L176-R179 PolarHBondContact O-N 3.13Å; R179-R183 WeakPolarHBondContact O-CB 3.48Å; R179-R183 PolarHBondContact O-N 3.03Å
180	S	98.6	Very high	98.1	Very high	74 Å²	74	61.1 Å²	61.1	52%	0.517	33%	0.325	S	S	.	.	H	α-helix	trans	-63.4	-46.3	176.7	-173.7	0	0	0	0	111.2	L176 W177 L178 S184	L176-S180 WeakPolarHBondContact O-CB 3.3Å; L176-S180 PolarHBondContact O-N 3.26Å; W177-S180 PolarHBondContact O-N 3.34Å; L178-S180 VanDerWaalsContact C-N 3.31Å; L178-S180 PolarHBondContact O-N 3.14Å; S180-S184 VanDerWaalsContact O-CB 3.31Å; S180-S184 WeakPolarHBondContact O-CB 3.19Å; S180-S184 PolarHBondContact O-N 2.85Å
181	V	98.7	Very high	98.1	Very high	7 Å²	7	59.5 Å²	59.5	4%	0.042	31%	0.313	C	S	.	.	H	α-helix	trans	-61.5	-51.1	175.9	172.3	0	0	0	0	111.2	W177 L178 R183 S184 L185 L227 L230 Y234 P247 F248	W177-V181 PolarHBondContact O-N 2.89Å; L178-V181 PolarHBondContact O-N 3.46Å; V181-R183 VanDerWaalsContact C-N 3.31Å; V181-R183 PolarHBondContact O-N 3.18Å; V181-S184 WeakPolarHBondContact O-CB 3.43Å; V181-S184 PolarHBondContact O-N 2.89Å; V181-S184 VanDerWaalsContact O-N 3.09Å; V181-L185 HydrophobicContact CG1-CD1 3.96Å; V181-L185 HydrophobicContact CG1-CG 4.47Å; V181-L185 WeakPolarHBondContact O-CG 3.28Å; V181-L185 PolarHBondContact O-N 2.93Å; V181-L227 HydrophobicContact CG2-CD2 3.78Å; V181-L230 HydrophobicContact CB-CD2 3.99Å; V181-L230 HydrophobicContact CG1-CD2 3.91Å; V181-L230 HydrophobicContact CG2-CD2 4.29Å; V181-Y234 HydrophobicContact CG1-CE2 4.33Å; V181-P247 HydrophobicContact CG1-CB 4.01Å; V181-P247 HydrophobicContact CG2-CB 4.37Å; V181-P247 WeakPolarHBondContact CG2-O 3.42Å; V181-F248 HydrophobicContact CG1-CD1 4.04Å; V181-F248 HydrophobicContact CG1-CE1 3.54Å; V181-F248 HydrophobicContact CG1-CE2 4.41Å; V181-F248 HydrophobicContact CG1-CZ 3.76Å
182	D	98.5	Very high	98	Very high	13 Å²	13	63.2 Å²	63.2	7%	0.07	33%	0.33	C	S	.	.	H	α-helix	trans	-60.8	-41.9	-177.7	-164.6	42.3	0	0	0	112.1	L178 L186 Q191 G194 F195 I196 Y234	L178-D182 PolarHBondContact O-N 2.98Å; L178-D182 VanDerWaalsContact O-N 3.12Å; D182-L186 PolarHBondContact O-N 3.35Å; D182-Q191 PolarHBondContact O-NE2 2.96Å; D182-Q191 PolarHBondContact OD1-NE2 2.99Å; D182-G194 WeakPolarHBondContact OD2-CA 3.48Å; D182-F195 WeakPolarHBondContact OD1-CB 3.49Å; D182-F195 PolarHBondContact OD1-N 3.49Å; D182-I196 HydrophobicContact CB-CG1 3.64Å; D182-I196 WeakPolarHBondContact OD2-CG1 3.27Å; D182-I196 PolarHBondContact OD2-N 3.39Å; D182-Y234 VanDerWaalsContact CA-OH 3.26Å; D182-Y234 WeakPolarHBondContact CA-OH 3.44Å; D182-Y234 VanDerWaalsContact CB-OH 3.25Å; D182-Y234 WeakPolarHBondContact CB-OH 3.49Å; D182-Y234 VanDerWaalsContact CG-OH 3.3Å; D182-Y234 PolarHBondContact OD1-OH 2.92Å
183	R	98.3	Very high	97.8	Very high	173 Å²	173	63.8 Å²	63.8	65%	0.653	33%	0.327	S	S	*	.	H	α-helix	trans	-66.5	-40	174.9	-174.3	175.8	-177.6	-87.1	-1.5	112	R179 V181 L186 L187	R179-R183 WeakPolarHBondContact O-CB 3.48Å; R179-R183 PolarHBondContact O-N 3.03Å; V181-R183 VanDerWaalsContact C-N 3.31Å; V181-R183 PolarHBondContact O-N 3.18Å; R183-L186 PolarHBondContact O-N 3.12Å; R183-L187 HydrophobicContact CG-CD1 3.91Å; R183-L187 HydrophobicContact CG-CG 4.31Å; R183-L187 WeakPolarHBondContact O-CB 3.32Å; R183-L187 VanDerWaalsContact O-CG 3.32Å; R183-L187 WeakPolarHBondContact O-CG 3.26Å; R183-L187 PolarHBondContact O-N 3.4Å
184	S	98.2	Very high	97.7	Very high	37 Å²	37	62.9 Å²	62.9	26%	0.259	33%	0.327	S	S	.	.	H	α-helix	trans	-62.5	-45.3	178.1	-175.7	0	0	0	0	111.4	S180 V181 L186 L187 Q188	S180-S184 VanDerWaalsContact O-CB 3.31Å; S180-S184 WeakPolarHBondContact O-CB 3.19Å; S180-S184 PolarHBondContact O-N 2.85Å; V181-S184 WeakPolarHBondContact O-CB 3.43Å; V181-S184 PolarHBondContact O-N 2.89Å; V181-S184 VanDerWaalsContact O-N 3.09Å; S184-L186 PolarHBondContact O-N 3.14Å; S184-L187 PolarHBondContact O-N 2.92Å; S184-Q188 VanDerWaalsContact O-CB 3.27Å; S184-Q188 WeakPolarHBondContact O-CB 3.19Å; S184-Q188 VanDerWaalsContact O-CG 3.27Å; S184-Q188 WeakPolarHBondContact O-CG 3.25Å; S184-Q188 PolarHBondContact O-N 3.18Å
185	L	98.4	Very high	97.7	Very high	0 Å²	0	63.3 Å²	63.3	0%	0	33%	0.329	C	S	.	.	H	α-helix	trans	-61.7	-43.6	178.8	-71.1	169.2	0	0	0	111.6	V181 Q188 G189 W190 Q191 Y234 Y243 P244 P247 F248	V181-L185 HydrophobicContact CG1-CD1 3.96Å; V181-L185 HydrophobicContact CG1-CG 4.47Å; V181-L185 WeakPolarHBondContact O-CG 3.28Å; V181-L185 PolarHBondContact O-N 2.93Å; L185-Q188 PolarHBondContact O-N 2.99Å; L185-G189 PolarHBondContact O-N 3.28Å; L185-W190 HydrophobicContact CB-CB 4.27Å; L185-W190 HydrophobicContact CD2-CB 3.81Å; L185-W190 HydrophobicContact CD2-CG 4.08Å; L185-W190 PolarHBondContact O-N 3.48Å; L185-Q191 HydrophobicContact CB-CG 4.1Å; L185-Y234 HydrophobicContact CD1-CD1 4.01Å; L185-Y234 HydrophobicContact CD1-CE1 3.44Å; L185-Y234 VanDerWaalsContact CD1-CE1 3.44Å; L185-Y234 HydrophobicContact CD1-CE2 4.31Å; L185-Y243 HydrophobicContact CD1-CD1 4.22Å; L185-P244 HydrophobicContact CD2-CG 3.63Å; L185-P247 HydrophobicContact CD2-CG 4.03Å; L185-F248 HydrophobicContact CD1-CE2 4.38Å; L185-F248 HydrophobicContact CD1-CZ 3.91Å
186	L	97.7	Very high	97.7	Very high	79 Å²	79	62.2 Å²	62.2	41%	0.414	32%	0.322	S	S	.	.	H	α-helix	trans	-64.3	-47.9	177.7	-169.5	152.8	0	0	0	111.6	D182 R183 S184 Q188 G189 Q191	D182-L186 PolarHBondContact O-N 3.35Å; R183-L186 PolarHBondContact O-N 3.12Å; S184-L186 PolarHBondContact O-N 3.14Å; L186-Q188 VanDerWaalsContact C-N 3.28Å; L186-Q188 PolarHBondContact O-N 3.5Å; L186-G189 PolarHBondContact O-N 3.36Å; L186-G189 VanDerWaalsContact O-N 3.15Å; L186-Q191 HydrophobicContact CB-CG 4.25Å
187	L	97.9	Very high	97.6	Very high	108 Å²	108	58 Å²	58	57%	0.565	30%	0.301	S	S	*	.	H	α-helix	trans	-68.4	-26.8	-178.6	-71.5	177.6	0	0	0	113.7	R183 S184 G189	R183-L187 HydrophobicContact CG-CD1 3.91Å; R183-L187 HydrophobicContact CG-CG 4.31Å; R183-L187 WeakPolarHBondContact O-CB 3.32Å; R183-L187 VanDerWaalsContact O-CG 3.32Å; R183-L187 WeakPolarHBondContact O-CG 3.26Å; R183-L187 PolarHBondContact O-N 3.4Å; S184-L187 PolarHBondContact O-N 2.92Å; L187-G189 VanDerWaalsContact C-N 3.31Å
188	Q	96.7	Very high	97.6	Very high	112 Å²	112	58.5 Å²	58.5	52%	0.523	31%	0.309	S	S	.	.	T	Hydrogen-bonded Turn	trans	-87.3	-0.2	176.5	-71.2	175.5	-12.1	0	0	112.9	S184 L185 L186	S184-Q188 VanDerWaalsContact O-CB 3.27Å; S184-Q188 WeakPolarHBondContact O-CB 3.19Å; S184-Q188 VanDerWaalsContact O-CG 3.27Å; S184-Q188 WeakPolarHBondContact O-CG 3.25Å; S184-Q188 PolarHBondContact O-N 3.18Å; L185-Q188 PolarHBondContact O-N 2.99Å; L186-Q188 VanDerWaalsContact C-N 3.28Å; L186-Q188 PolarHBondContact O-N 3.5Å
189	G	97	Very high	97.5	Very high	66 Å²	66	59 Å²	59	68%	0.68	31%	0.313	S	S	*	.	T	Hydrogen-bonded Turn	trans	74.4	23.5	178	0	0	0	0	0	114.2	L185 L186 L187	L185-G189 PolarHBondContact O-N 3.28Å; L186-G189 PolarHBondContact O-N 3.36Å; L186-G189 VanDerWaalsContact O-N 3.15Å; L187-G189 VanDerWaalsContact C-N 3.31Å
190	W	97.8	Very high	97.5	Very high	112 Å²	112	55.1 Å²	55.1	42%	0.424	30%	0.3	S	S	.	.	S	Bend	trans	-82.5	-14.1	174.5	-73.4	102.4	0	0	0	113.4	L185 E240 P244	L185-W190 HydrophobicContact CB-CB 4.27Å; L185-W190 HydrophobicContact CD2-CB 3.81Å; L185-W190 HydrophobicContact CD2-CG 4.08Å; L185-W190 PolarHBondContact O-N 3.48Å; W190-E240 WeakPolarHBondContact O-CG 3.31Å; W190-P244 HydrophobicContact CD2-CB 4.31Å; W190-P244 HydrophobicContact CD2-CG 3.65Å; W190-P244 HydrophobicContact CE3-CG 4.21Å; W190-P244 HydrophobicContact CG-CG 3.85Å; W190-P244 HydrophobicContact CH2-CB 4.16Å; W190-P244 HydrophobicContact CZ2-CB 3.81Å; W190-P244 HydrophobicContact CZ2-CG 4.03Å
191	Q	96.4	Very high	97.5	Very high	9 Å²	9	51.6 Å²	51.6	4%	0.042	28%	0.275	C	S	.	.			trans	-153	147.9	177.6	64.5	-176.8	7.9	0	0	110.7	D182 L185 L186 Q193 E240	D182-Q191 PolarHBondContact O-NE2 2.96Å; D182-Q191 PolarHBondContact OD1-NE2 2.99Å; L185-Q191 HydrophobicContact CB-CG 4.1Å; L186-Q191 HydrophobicContact CB-CG 4.25Å; Q191-Q193 VanDerWaalsContact CD-O 3.23Å; Q191-Q193 WeakPolarHBondContact CG-O 3.46Å; Q191-Q193 PolarHBondContact OE1-O 2.95Å; Q191-E240 HydrophobicContact CB-CG 4.02Å
192	D	95.5	Very high	97.5	Very high	122 Å²	122	51.3 Å²	51.3	65%	0.652	27%	0.273	S	S	*	.	S	Bend	trans	-83.7	-28.2	177.8	-69.8	-38.3	0	0	0	113	N82	N82-D192 PolarHBondContact ND2-OD2 3.22Å
193	Q	94.5	Very high	97.5	Very high	98 Å²	98	50.8 Å²	50.8	46%	0.458	27%	0.271	S	S	.	.	S	Bend	trans	-131.3	146.7	-178.5	-176.1	176.1	-32.4	0	0	110.2	Q191 F195	Q191-Q193 VanDerWaalsContact CD-O 3.23Å; Q191-Q193 WeakPolarHBondContact CG-O 3.46Å; Q191-Q193 PolarHBondContact OE1-O 2.95Å; Q193-F195 PolarHBondContact O-N 3.42Å
194	G	95.8	Very high	97.5	Very high	23 Å²	23	42.6 Å²	42.6	24%	0.237	24%	0.24	C	C	.	.			trans	-62.4	134.6	174.4	0	0	0	0	0	112.1	D182 I196	D182-G194 WeakPolarHBondContact OD2-CA 3.48Å; G194-I196 VanDerWaalsContact C-N 3.33Å
195	F	98.3	Very high	97.5	Very high	11 Å²	11	41.3 Å²	41.3	5%	0.048	23%	0.229	C	C	.	.	S	Bend	trans	-72.7	-28.2	178.5	173.7	-100.5	0	0	0	112.3	D182 Q193 T197 N200 L230 S233 Y234 M237	D182-F195 WeakPolarHBondContact OD1-CB 3.49Å; D182-F195 PolarHBondContact OD1-N 3.49Å; Q193-F195 PolarHBondContact O-N 3.42Å; F195-T197 PolarHBondContact O-N 3.44Å; F195-N200 HydrophobicContact CD1-CB 4.36Å; F195-N200 WeakPolarHBondContact CD2-ND2 3.27Å; F195-N200 HydrophobicContact CE1-CB 3.87Å; F195-N200 HydrophobicContact CE2-CB 4.22Å; F195-N200 VanDerWaalsContact CE2-ND2 3.35Å; F195-N200 WeakPolarHBondContact CE2-ND2 3.45Å; F195-N200 HydrophobicContact CZ-CB 3.78Å; F195-N200 WeakPolarHBondContact O-CB 3.23Å; F195-N200 PolarHBondContact O-ND2 3.09Å; F195-L230 HydrophobicContact CE1-CD1 4.27Å; F195-S233 VanDerWaalsContact CZ-C 3.48Å; F195-S233 WeakPolarHBondContact CZ-O 3.29Å; F195-Y234 HydrophobicContact CB-CD1 3.88Å; F195-Y234 HydrophobicContact CB-CE1 3.15Å; F195-Y234 HydrophobicContact CB-CE2 4.34Å; F195-Y234 VanDerWaalsContact CB-CZ 3.43Å; F195-Y234 HydrophobicContact CD1-CD1 4.16Å; F195-Y234 AromaticContact CD1-CD2 3.91Å; F195-Y234 HydrophobicContact CD1-CD2 3.91Å; F195-Y234 AromaticContact CD1-CE1 3.86Å; F195-Y234 HydrophobicContact CD1-CE1 3.86Å; F195-Y234 AromaticContact CD1-CE2 3.58Å; F195-Y234 HydrophobicContact CD1-CE2 3.58Å; F195-Y234 HydrophobicContact CD1-CG 4.19Å; F195-Y234 AromaticContact CD1-CZ 3.55Å; F195-Y234 AromaticContact CD2-CD1 3.95Å; F195-Y234 HydrophobicContact CD2-CD1 3.95Å; F195-Y234 HydrophobicContact CD2-CE1 4.11Å; F195-Y234 HydrophobicContact CD2-CG 4.35Å; F195-Y234 HydrophobicContact CE1-CD2 4.1Å; F195-Y234 HydrophobicContact CE1-CE2 4.14Å; F195-Y234 HydrophobicContact CE1-CG 4.42Å; F195-Y234 AromaticContact CG-CD1 3.73Å; F195-Y234 HydrophobicContact CG-CD1 3.73Å; F195-Y234 HydrophobicContact CG-CD2 4.33Å; F195-Y234 AromaticContact CG-CE1 3.45Å; F195-Y234 HydrophobicContact CG-CE1 3.45Å; F195-Y234 VanDerWaalsContact CG-CE1 3.45Å; F195-Y234 HydrophobicContact CG-CE2 4.08Å; F195-Y234 HydrophobicContact CG-CG 4.17Å; F195-Y234 AromaticContact CG-CZ 3.63Å; F195-M237 HydrophobicContact CE2-CB 3.86Å; F195-M237 HydrophobicContact CZ-CB 4.14Å
196	I	98.3	Very high	97.5	Very high	13 Å²	13	41.3 Å²	41.3	7%	0.067	23%	0.229	C	C	.	.			trans	-73.7	88.3	-173.3	-58.1	-68	0	0	0	110.4	T148 L152 L178 D182 G194 V201 L230	T148-I196 HydrophobicContact CG2-CG2 3.66Å; T148-I196 WeakPolarHBondContact CG2-O 3.29Å; L152-I196 HydrophobicContact CD1-CG2 3.77Å; L152-I196 HydrophobicContact CD2-CG2 4.14Å; L152-I196 HydrophobicContact CG-CG2 4.28Å; L178-I196 HydrophobicContact CB-CD1 4.47Å; D182-I196 HydrophobicContact CB-CG1 3.64Å; D182-I196 WeakPolarHBondContact OD2-CG1 3.27Å; D182-I196 PolarHBondContact OD2-N 3.39Å; G194-I196 VanDerWaalsContact C-N 3.33Å; I196-V201 HydrophobicContact CG2-CG2 4.03Å; I196-L230 HydrophobicContact CD1-CD1 4.33Å
197	T	97.5	Very high	97.6	Very high	24 Å²	24	37.5 Å²	37.5	15%	0.147	21%	0.209	C	C	.	.			trans	-117.4	163.4	176.6	66.3	0	0	0	0	110.3	F195 A199 N200 V201	F195-T197 PolarHBondContact O-N 3.44Å; T197-A199 VanDerWaalsContact C-N 3.32Å; T197-A199 PolarHBondContact O-N 3.29Å; T197-N200 PolarHBondContact O-N 2.84Å; T197-N200 PolarHBondContact OG1-N 3.24Å; T197-N200 PolarHBondContact OG1-ND2 2.85Å; T197-V201 WeakPolarHBondContact O-CG2 3.48Å; T197-V201 PolarHBondContact O-N 3.44Å
198	P	97.5	Very high	97.6	Very high	49 Å²	49	32.4 Å²	32.4	32%	0.318	18%	0.183	S	C	.	.	H	α-helix	trans	-53.5	-45.8	179.9	-29.2	37.9	0	0	0	113.6	T148 L151 N200 V201 V202	T148-P198 WeakPolarHBondContact OG1-CD 3.27Å; L151-P198 HydrophobicContact CD1-CB 3.69Å; P198-N200 PolarHBondContact O-N 3.23Å; P198-V201 PolarHBondContact O-N 3Å; P198-V202 WeakPolarHBondContact O-CG2 3.35Å; P198-V202 PolarHBondContact O-N 3.09Å; P198-V202 VanDerWaalsContact O-N 3.11Å
199	A	96.9	Very high	97.7	Very high	11 Å²	11	29 Å²	29	9%	0.091	17%	0.165	C	C	.	.	H	α-helix	trans	-63.8	-41.6	179.5	0	0	0	0	0	112.6	A93 T197 V201 V202 F203 F282	A93-A199 HydrophobicContact CB-CB 3.75Å; T197-A199 VanDerWaalsContact C-N 3.32Å; T197-A199 PolarHBondContact O-N 3.29Å; A199-V201 VanDerWaalsContact C-N 3.34Å; A199-V201 PolarHBondContact O-N 2.94Å; A199-V202 WeakPolarHBondContact O-CB 3.42Å; A199-V202 PolarHBondContact O-N 2.98Å; A199-F203 PolarHBondContact O-N 3.1Å; A199-F282 HydrophobicContact CB-CE2 4.09Å; A199-F282 HydrophobicContact CB-CZ 4.1Å
200	N	98.4	Very high	97.8	Very high	17 Å²	17	28.8 Å²	28.8	9%	0.091	15%	0.148	C	C	.	.	H	α-helix	trans	-71.9	-29	-179.9	-68.4	-13.3	0	0	0	112.4	F195 T197 P198 F203 L204	F195-N200 HydrophobicContact CD1-CB 4.36Å; F195-N200 WeakPolarHBondContact CD2-ND2 3.27Å; F195-N200 HydrophobicContact CE1-CB 3.87Å; F195-N200 HydrophobicContact CE2-CB 4.22Å; F195-N200 VanDerWaalsContact CE2-ND2 3.35Å; F195-N200 WeakPolarHBondContact CE2-ND2 3.45Å; F195-N200 HydrophobicContact CZ-CB 3.78Å; F195-N200 WeakPolarHBondContact O-CB 3.23Å; F195-N200 PolarHBondContact O-ND2 3.09Å; T197-N200 PolarHBondContact O-N 2.84Å; T197-N200 PolarHBondContact OG1-N 3.24Å; T197-N200 PolarHBondContact OG1-ND2 2.85Å; P198-N200 PolarHBondContact O-N 3.23Å; N200-F203 PolarHBondContact O-N 3.49Å; N200-L204 WeakPolarHBondContact O-CB 3.25Å; N200-L204 PolarHBondContact O-N 2.92Å
201	V	98.6	Very high	97.8	Very high	0 Å²	0	24.9 Å²	24.9	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-69.4	-38.2	171.7	178	0	0	0	0	111	T148 L151 L152 L155 I196 T197 P198 A199 L204 Y205 L289	T148-V201 HydrophobicContact CG2-CG2 4.24Å; L151-V201 HydrophobicContact CB-CB 4.35Å; L151-V201 HydrophobicContact CB-CG1 3.81Å; L152-V201 HydrophobicContact CD2-CG1 4.32Å; L152-V201 HydrophobicContact CD2-CG2 3.88Å; L152-V201 HydrophobicContact CG-CG2 4.08Å; L155-V201 HydrophobicContact CD2-CG1 4.44Å; I196-V201 HydrophobicContact CG2-CG2 4.03Å; T197-V201 WeakPolarHBondContact O-CG2 3.48Å; T197-V201 PolarHBondContact O-N 3.44Å; P198-V201 PolarHBondContact O-N 3Å; A199-V201 VanDerWaalsContact C-N 3.34Å; A199-V201 PolarHBondContact O-N 2.94Å; V201-L204 PolarHBondContact O-N 3.39Å; V201-Y205 WeakPolarHBondContact O-CB 3.47Å; V201-Y205 PolarHBondContact O-N 3.5Å; V201-L289 HydrophobicContact CG1-CD2 4.06Å
202	V	98.4	Very high	97.9	Very high	0 Å²	0	24.6 Å²	24.6	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-63.2	-44.3	173.5	177.4	0	0	0	0	110.6	L151 P198 A199 Y205 M206 I275 F282 V285 F286 L289	L151-V202 HydrophobicContact CD1-CG2 4.48Å; P198-V202 WeakPolarHBondContact O-CG2 3.35Å; P198-V202 PolarHBondContact O-N 3.09Å; P198-V202 VanDerWaalsContact O-N 3.11Å; A199-V202 WeakPolarHBondContact O-CB 3.42Å; A199-V202 PolarHBondContact O-N 2.98Å; V202-Y205 PolarHBondContact O-N 3.41Å; V202-M206 PolarHBondContact O-N 2.86Å; V202-I275 HydrophobicContact CG1-CD1 4.33Å; V202-F282 HydrophobicContact CB-CE2 3.99Å; V202-F282 HydrophobicContact CB-CZ 4.34Å; V202-F282 HydrophobicContact CG1-CD2 4.13Å; V202-F282 HydrophobicContact CG1-CE2 3.84Å; V202-F282 HydrophobicContact CG1-CZ 4.31Å; V202-F282 HydrophobicContact CG2-CE2 4.41Å; V202-F282 HydrophobicContact CG2-CZ 4.27Å; V202-V285 HydrophobicContact CG1-CB 3.93Å; V202-V285 HydrophobicContact CG1-CG1 3.55Å; V202-F286 HydrophobicContact CG1-CB 4.19Å; V202-F286 HydrophobicContact CG2-CB 4.15Å; V202-F286 HydrophobicContact CG2-CD2 3.54Å; V202-F286 HydrophobicContact CG2-CE2 4.41Å; V202-F286 HydrophobicContact CG2-CG 4.29Å; V202-L289 HydrophobicContact CG2-CD2 4.25Å
203	F	98.7	Very high	98.1	Very high	3 Å²	3	21.8 Å²	21.8	1%	0.013	13%	0.125	C	C	.	.	H	α-helix	trans	-59.9	-46.9	175.1	-172.9	-83.8	0	0	0	111.7	A199 N200 Y205 M206 L207 Y236 M237 M272 I275	A199-F203 PolarHBondContact O-N 3.1Å; N200-F203 PolarHBondContact O-N 3.49Å; F203-Y205 PolarHBondContact O-N 3.03Å; F203-M206 HydrophobicContact CD2-CE 4.39Å; F203-M206 HydrophobicContact CE2-CE 4.23Å; F203-M206 HydrophobicContact CZ-CE 4.47Å; F203-M206 WeakPolarHBondContact O-CB 3.21Å; F203-M206 PolarHBondContact O-N 3.01Å; F203-L207 HydrophobicContact CD1-CD1 4.38Å; F203-L207 HydrophobicContact CE1-CD1 3.98Å; F203-L207 HydrophobicContact CE1-CG 4.31Å; F203-L207 PolarHBondContact O-N 3.49Å; F203-Y236 AromaticContact CE2-CD1 3.82Å; F203-Y236 HydrophobicContact CE2-CD1 3.82Å; F203-Y236 HydrophobicContact CE2-CE1 4.06Å; F203-Y236 AromaticContact CZ-CD1 3.51Å; F203-Y236 HydrophobicContact CZ-CD1 3.51Å; F203-Y236 HydrophobicContact CZ-CE1 4.12Å; F203-Y236 HydrophobicContact CZ-CG 4.13Å; F203-M237 HydrophobicContact CB-CG 4.48Å; F203-M237 HydrophobicContact CD1-CG 3.85Å; F203-M237 HydrophobicContact CD2-CE 4.3Å; F203-M237 HydrophobicContact CD2-CG 3.69Å; F203-M237 HydrophobicContact CD2-SD 3.69Å; F203-M237 HydrophobicContact CE1-CG 3.91Å; F203-M237 HydrophobicContact CE2-CG 3.75Å; F203-M237 HydrophobicContact CE2-SD 3.68Å; F203-M237 HydrophobicContact CG-CG 3.74Å; F203-M237 HydrophobicContact CG-SD 4.32Å; F203-M237 HydrophobicContact CZ-CG 3.85Å; F203-M237 HydrophobicContact CZ-SD 4.29Å; F203-M272 HydrophobicContact CE1-CE 4.13Å; F203-M272 HydrophobicContact CE1-CG 4.42Å; F203-M272 HydrophobicContact CE2-CB 4.15Å; F203-M272 HydrophobicContact CE2-CG 4.31Å; F203-M272 HydrophobicContact CZ-CB 3.87Å; F203-M272 HydrophobicContact CZ-CE 3.72Å; F203-M272 HydrophobicContact CZ-CG 3.68Å; F203-I275 HydrophobicContact CD2-CG2 3.58Å; F203-I275 HydrophobicContact CE2-CG2 3.72Å
204	L	98.9	Very high	98.2	Very high	1 Å²	1	19.3 Å²	19.3	1%	0.005	12%	0.119	C	C	.	.	H	α-helix	trans	-61.2	-44	176.9	177.9	62.4	0	0	0	111.8	L155 L178 N200 V201 M206 L207 C208 L226 C229 L230	L155-L204 HydrophobicContact CD2-CD2 3.8Å; L155-L204 HydrophobicContact CD2-CG 4.21Å; L178-L204 HydrophobicContact CD1-CD2 3.7Å; L178-L204 HydrophobicContact CD2-CD2 3.8Å; L178-L204 HydrophobicContact CG-CD2 4.41Å; N200-L204 WeakPolarHBondContact O-CB 3.25Å; N200-L204 PolarHBondContact O-N 2.92Å; V201-L204 PolarHBondContact O-N 3.39Å; L204-M206 VanDerWaalsContact C-N 3.31Å; L204-M206 PolarHBondContact O-N 2.93Å; L204-L207 WeakPolarHBondContact O-CB 3.45Å; L204-L207 PolarHBondContact O-N 3.26Å; L204-C208 PolarHBondContact O-N 3.44Å; L204-C208 PolarHBondContact O-SG 3.18Å; L204-L226 HydrophobicContact CD1-CD1 4.49Å; L204-C229 HydrophobicContact CD1-CB 3.85Å; L204-L230 HydrophobicContact CD1-CB 4.37Å; L204-L230 HydrophobicContact CD1-CD1 4.46Å; L204-L230 HydrophobicContact CD2-CD1 4.03Å
205	Y	98.8	Very high	98.3	Very high	9 Å²	9	22.3 Å²	22.3	4%	0.035	13%	0.127	C	C	.	.	H	α-helix	trans	-59.6	-41.4	175.6	167.1	-109	0	0	0	112	L155 F158 V201 V202 F203 L207 C208 R209 V285 D288 L289 E292	L155-Y205 HydrophobicContact CD1-CD2 4Å; F158-Y205 HydrophobicContact CB-CE2 4.47Å; F158-Y205 HydrophobicContact CD1-CD2 4.09Å; F158-Y205 HydrophobicContact CD1-CE2 4.05Å; F158-Y205 AromaticContact CD2-CE2 3.87Å; F158-Y205 HydrophobicContact CD2-CE2 3.87Å; F158-Y205 HydrophobicContact CE1-CD2 4.43Å; F158-Y205 HydrophobicContact CE1-CE2 4.35Å; F158-Y205 HydrophobicContact CE2-CE2 4.17Å; F158-Y205 HydrophobicContact CG-CD2 4.26Å; F158-Y205 AromaticContact CG-CE2 3.83Å; F158-Y205 HydrophobicContact CG-CE2 3.83Å; F158-Y205 HydrophobicContact CZ-CE2 4.44Å; V201-Y205 WeakPolarHBondContact O-CB 3.47Å; V201-Y205 PolarHBondContact O-N 3.5Å; V202-Y205 PolarHBondContact O-N 3.41Å; F203-Y205 PolarHBondContact O-N 3.03Å; Y205-L207 VanDerWaalsContact C-N 3.27Å; Y205-L207 PolarHBondContact O-N 3.22Å; Y205-C208 PolarHBondContact O-N 3.31Å; Y205-C208 VanDerWaalsContact O-N 3.14Å; Y205-R209 HydrophobicContact CE2-CB 4.16Å; Y205-R209 WeakPolarHBondContact O-CG 3.28Å; Y205-R209 PolarHBondContact O-N 2.92Å; Y205-V285 HydrophobicContact CD1-CG1 3.7Å; Y205-V285 HydrophobicContact CE1-CG1 4.1Å; Y205-D288 HydrophobicContact CE1-CB 3.97Å; Y205-L289 HydrophobicContact CD1-CB 3.67Å; Y205-L289 HydrophobicContact CD1-CD1 4.25Å; Y205-L289 HydrophobicContact CD1-CD2 4.47Å; Y205-L289 HydrophobicContact CD1-CG 4.33Å; Y205-L289 HydrophobicContact CD2-CD1 3.79Å; Y205-L289 HydrophobicContact CE1-CB 3.87Å; Y205-L289 HydrophobicContact CE2-CD1 4.3Å; Y205-L289 HydrophobicContact CG-CB 4.08Å; Y205-L289 HydrophobicContact CG-CD1 3.76Å; Y205-L289 HydrophobicContact CG-CD2 4.29Å; Y205-L289 HydrophobicContact CG-CG 4.25Å; Y205-E292 HydrophobicContact CE2-CG 4.16Å; Y205-E292 PolarHBondContact OH-OE1 3.32Å; Y205-E292 VanDerWaalsContact OH-OE1 3.13Å
206	M	98.7	Very high	98.3	Very high	0 Å²	0	22 Å²	22	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-57.4	-39.3	175.2	-178	-84.3	-67	0	0	112.2	V202 F203 L204 R209 M268 K271 M272 I275 V285	V202-M206 PolarHBondContact O-N 2.86Å; F203-M206 HydrophobicContact CD2-CE 4.39Å; F203-M206 HydrophobicContact CE2-CE 4.23Å; F203-M206 HydrophobicContact CZ-CE 4.47Å; F203-M206 WeakPolarHBondContact O-CB 3.21Å; F203-M206 PolarHBondContact O-N 3.01Å; L204-M206 VanDerWaalsContact C-N 3.31Å; L204-M206 PolarHBondContact O-N 2.93Å; M206-R209 WeakPolarHBondContact O-CG 3.46Å; M206-M268 WeakPolarHBondContact O-CE 3.49Å; M206-M268 HydrophobicContact SD-CE 3.25Å; M206-M268 WeakPolarHBondContact SD-CE 3.38Å; M206-K271 HydrophobicContact CE-CB 4.25Å; M206-K271 HydrophobicContact SD-CB 3.64Å; M206-K271 HydrophobicContact SD-CD 4.42Å; M206-M272 HydrophobicContact CE-CB 4.46Å; M206-M272 HydrophobicContact CE-CG 3.95Å; M206-I275 HydrophobicContact CB-CD1 4.02Å; M206-I275 HydrophobicContact CE-CG2 4.05Å; M206-I275 HydrophobicContact CG-CD1 4.14Å; M206-V285 HydrophobicContact CB-CG1 3.88Å; M206-V285 HydrophobicContact CG-CG2 4.43Å
207	L	98.8	Very high	98.3	Very high	0 Å²	0	23.3 Å²	23.3	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-66.8	-52.5	171.6	-60.7	-177.8	0	0	0	111.3	F203 L204 Y205 R209 D210 V211 C229 S233 M268 M272	F203-L207 HydrophobicContact CD1-CD1 4.38Å; F203-L207 HydrophobicContact CE1-CD1 3.98Å; F203-L207 HydrophobicContact CE1-CG 4.31Å; F203-L207 PolarHBondContact O-N 3.49Å; L204-L207 WeakPolarHBondContact O-CB 3.45Å; L204-L207 PolarHBondContact O-N 3.26Å; Y205-L207 VanDerWaalsContact C-N 3.27Å; Y205-L207 PolarHBondContact O-N 3.22Å; L207-R209 VanDerWaalsContact C-N 3.29Å; L207-R209 PolarHBondContact O-N 3.12Å; L207-D210 PolarHBondContact O-N 3.39Å; L207-V211 VanDerWaalsContact O-CB 3.29Å; L207-V211 WeakPolarHBondContact O-CB 3.46Å; L207-V211 VanDerWaalsContact O-CG2 3.23Å; L207-V211 WeakPolarHBondContact O-CG2 3.31Å; L207-V211 PolarHBondContact O-N 2.86Å; L207-C229 HydrophobicContact CB-CB 4.17Å; L207-C229 HydrophobicContact CD1-CB 4.3Å; L207-C229 WeakPolarHBondContact CD1-O 3.35Å; L207-S233 WeakPolarHBondContact CD1-OG 3.46Å; L207-M268 HydrophobicContact CD2-CB 3.71Å; L207-M268 HydrophobicContact CD2-CE 4.11Å; L207-M268 HydrophobicContact CD2-CG 3.94Å; L207-M272 HydrophobicContact CD2-CG 3.77Å; L207-M272 HydrophobicContact CD2-SD 4.01Å
208	C	98.8	Very high	98.3	Very high	0 Å²	0	24.5 Å²	24.5	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-58	-40.1	-173.9	-67.5	0	0	0	0	112.7	L155 F158 L159 L204 Y205 D210 V211 I212 L226	L155-C208 HydrophobicContact CD1-CB 4.31Å; F158-C208 HydrophobicContact CE1-CB 4.05Å; L159-C208 HydrophobicContact CD2-CB 4.46Å; L204-C208 PolarHBondContact O-N 3.44Å; L204-C208 PolarHBondContact O-SG 3.18Å; Y205-C208 PolarHBondContact O-N 3.31Å; Y205-C208 VanDerWaalsContact O-N 3.14Å; C208-D210 PolarHBondContact O-N 3.29Å; C208-V211 PolarHBondContact O-N 3.48Å; C208-I212 HydrophobicContact CB-CD1 3.79Å; C208-I212 HydrophobicContact CB-CG1 4.43Å; C208-I212 WeakPolarHBondContact O-CB 3.37Å; C208-I212 PolarHBondContact O-N 3.35Å; C208-L226 WeakPolarHBondContact SG-CD1 3.44Å
209	R	98.4	Very high	98.3	Very high	40 Å²	40	24.7 Å²	24.7	15%	0.151	15%	0.15	C	C	.	.	H	α-helix	trans	-64.8	-27	-177.5	71.5	178	-174	177.3	-0.9	114	F158 R162 Y205 M206 L207 Y281 D288	F158-R209 HydrophobicContact CE2-CB 4.33Å; F158-R209 HydrophobicContact CZ-CB 4.01Å; R162-R209 VanDerWaalsContact CZ-O 3.28Å; R162-R209 PolarHBondContact NH1-O 3.02Å; R162-R209 PolarHBondContact NH2-O 3.42Å; Y205-R209 HydrophobicContact CE2-CB 4.16Å; Y205-R209 WeakPolarHBondContact O-CG 3.28Å; Y205-R209 PolarHBondContact O-N 2.92Å; M206-R209 WeakPolarHBondContact O-CG 3.46Å; L207-R209 VanDerWaalsContact C-N 3.29Å; L207-R209 PolarHBondContact O-N 3.12Å; R209-Y281 PolarHBondContact NH2-OH 3.35Å; R209-D288 IonicContact NH1-OD2 2.62Å; R209-D288 PolarHBondContact NH1-OD2 3.04Å
210	D	98.4	Very high	98.4	Very high	63 Å²	63	28.8 Å²	28.8	34%	0.337	17%	0.167	S	C	.	.	H	α-helix	trans	-104.9	-21.2	-178.8	-66.8	-28.3	0	0	0	112.9	L207 C208 M268 K271	L207-D210 PolarHBondContact O-N 3.39Å; C208-D210 PolarHBondContact O-N 3.29Å; D210-M268 HydrophobicContact CB-CE 3.82Å; D210-M268 HydrophobicContact CB-SD 3.6Å; D210-M268 WeakPolarHBondContact OD2-CE 3.31Å; D210-K271 IonicContact OD1-NZ 4Å; D210-K271 WeakPolarHBondContact OD2-CD 3.48Å; D210-K271 IonicContact OD2-NZ 3.92Å; D210-K271 PolarHBondContact OD2-NZ 3.11Å
211	V	98.7	Very high	98.4	Very high	30 Å²	30	32 Å²	32	18%	0.182	18%	0.182	C	C	.	.	H	α-helix	trans	-96.4	-40.6	-177.1	174.1	0	0	0	0	113.1	L207 C208 S213 V225 V264 L267 M268	L207-V211 VanDerWaalsContact O-CB 3.29Å; L207-V211 WeakPolarHBondContact O-CB 3.46Å; L207-V211 VanDerWaalsContact O-CG2 3.23Å; L207-V211 WeakPolarHBondContact O-CG2 3.31Å; L207-V211 PolarHBondContact O-N 2.86Å; C208-V211 PolarHBondContact O-N 3.48Å; V211-S213 PolarHBondContact O-N 2.97Å; V211-V225 HydrophobicContact CG1-CG1 3.9Å; V211-V264 HydrophobicContact CB-CG2 4.39Å; V211-V264 HydrophobicContact CG1-CG2 3.54Å; V211-V264 HydrophobicContact CG2-CB 4.37Å; V211-V264 HydrophobicContact CG2-CG1 3.76Å; V211-V264 HydrophobicContact CG2-CG2 3.86Å; V211-L267 HydrophobicContact CG2-CD2 4.49Å; V211-M268 HydrophobicContact CG2-CG 3.85Å; V211-M268 HydrophobicContact CG2-SD 4.36Å
212	I	98.6	Very high	98.4	Very high	3 Å²	3	32 Å²	32	2%	0.015	18%	0.182	C	C	.	.	S	Bend	trans	-81.7	111.1	-172.2	-63.6	175.4	0	0	0	109.6	L159 R162 C208 V216 L222 V225 L226	L159-I212 HydrophobicContact CD2-CD1 3.42Å; L159-I212 VanDerWaalsContact CD2-CD1 3.42Å; L159-I212 HydrophobicContact CD2-CG2 4.39Å; R162-I212 HydrophobicContact CG-CG2 4.36Å; R162-I212 PolarHBondContact NH1-O 3.43Å; C208-I212 HydrophobicContact CB-CD1 3.79Å; C208-I212 HydrophobicContact CB-CG1 4.43Å; C208-I212 WeakPolarHBondContact O-CB 3.37Å; C208-I212 PolarHBondContact O-N 3.35Å; I212-V216 HydrophobicContact CG2-CG2 4.27Å; I212-L222 HydrophobicContact CD1-CD1 4.13Å; I212-L222 HydrophobicContact CG2-CD1 3.84Å; I212-V225 HydrophobicContact CG1-CG1 3.72Å; I212-L226 HydrophobicContact CD1-CB 4.49Å; I212-L226 HydrophobicContact CD1-CD1 4.35Å
213	S	98.2	Very high	98.4	Very high	62 Å²	62	34.1 Å²	34.1	43%	0.434	19%	0.192	S	C	.	.			trans	-63.2	148.5	178	-179.2	0	0	0	0	111.8	V211 E215 V216	V211-S213 PolarHBondContact O-N 2.97Å; S213-E215 PolarHBondContact O-N 2.97Å; S213-E215 PolarHBondContact OG-N 3.48Å; S213-E215 VanDerWaalsContact OG-N 3.1Å; S213-V216 WeakPolarHBondContact O-CG2 3.34Å
214	S	98.1	Very high	98.4	Very high	47 Å²	47	34 Å²	34	33%	0.329	19%	0.192	S	C	.	.	T	Hydrogen-bonded Turn	trans	-66	-22.3	168.4	54.3	0	0	0	0	112.7	R162 Y164 V216	R162-S214 VanDerWaalsContact O-CA 3.29Å; R162-S214 WeakPolarHBondContact O-CA 3.32Å; Y164-S214 VanDerWaalsContact CD1-O 3.3Å; Y164-S214 WeakPolarHBondContact CD1-O 3.21Å; Y164-S214 WeakPolarHBondContact CE1-O 3.26Å; S214-V216 PolarHBondContact O-N 3.48Å
215	E	98.1	Very high	98.4	Very high	86 Å²	86	34.8 Å²	34.8	40%	0.402	20%	0.196	S	C	.	.	T	Hydrogen-bonded Turn	trans	-88.7	3.7	-172.3	-56.2	-49.3	123.8	0	0	114.6	Y164 R165 S213 G217	Y164-E215 VanDerWaalsContact CE1-OE1 3.27Å; Y164-E215 WeakPolarHBondContact CE1-OE1 3.34Å; Y164-E215 VanDerWaalsContact OH-CD 3.24Å; Y164-E215 PolarHBondContact OH-OE1 3.24Å; Y164-E215 PolarHBondContact OH-OE2 2.99Å; R165-E215 PolarHBondContact NH1-O 3.04Å; S213-E215 PolarHBondContact O-N 2.97Å; S213-E215 PolarHBondContact OG-N 3.48Å; S213-E215 VanDerWaalsContact OG-N 3.1Å; E215-G217 PolarHBondContact O-N 3.19Å
216	V	98	Very high	98.4	Very high	4 Å²	4	34.3 Å²	34.3	2%	0.024	19%	0.194	C	C	.	.			trans	-50.4	124.9	177.4	171.9	0	0	0	0	110.1	L166 I212 S213 S214 S218 E221 L222	L166-V216 HydrophobicContact CD1-CG1 4.27Å; I212-V216 HydrophobicContact CG2-CG2 4.27Å; S213-V216 WeakPolarHBondContact O-CG2 3.34Å; S214-V216 PolarHBondContact O-N 3.48Å; V216-S218 WeakPolarHBondContact CG1-O 3.45Å; V216-E221 HydrophobicContact CG1-CB 4.04Å; V216-E221 HydrophobicContact CG1-CG 4.01Å; V216-L222 HydrophobicContact CG1-CB 3.88Å
217	G	97.4	Very high	98.4	Very high	41 Å²	41	34.5 Å²	34.5	42%	0.423	20%	0.195	S	C	.	.			trans	-96.5	-12.5	-165.4	0	0	0	0	0	115.1	E215 E221	E215-G217 PolarHBondContact O-N 3.19Å; G217-E221 PolarHBondContact N-OE2 2.85Å
218	S	98.2	Very high	98.4	Very high	49 Å²	49	34.5 Å²	34.5	34%	0.343	20%	0.195	S	C	.	.			trans	-149.8	156.7	177.4	68.2	0	0	0	0	113.4	L166 V216 H220 E221 L222	L166-S218 VanDerWaalsContact CD2-CA 3.42Å; V216-S218 WeakPolarHBondContact CG1-O 3.45Å; S218-H220 PolarHBondContact O-N 3.47Å; S218-E221 PolarHBondContact O-N 3.38Å; S218-E221 VanDerWaalsContact OG-CB 3.32Å; S218-E221 WeakPolarHBondContact OG-CB 3.38Å; S218-E221 PolarHBondContact OG-N 2.81Å; S218-E221 VanDerWaalsContact OG-N 3.1Å; S218-L222 PolarHBondContact O-N 2.94Å
219	D	98.1	Very high	98.4	Very high	52 Å²	52	34.5 Å²	34.5	28%	0.278	20%	0.195	S	C	.	.	H	α-helix	trans	-62	-32.5	175	-64.1	10.9	0	0	0	111.7	L222 Q223	D219-L222 PolarHBondContact O-N 2.88Å; D219-Q223 WeakPolarHBondContact O-CB 3.4Å; D219-Q223 PolarHBondContact O-N 3.25Å
220	H	98.2	Very high	98.5	Very high	97 Å²	97	32.6 Å²	32.6	45%	0.449	19%	0.188	S	C	.	.	H	α-helix	trans	-66.8	-43.8	175.8	177.7	-94.1	0	0	0	111.9	S218 Q223 A224 V250	S218-H220 PolarHBondContact O-N 3.47Å; H220-Q223 PolarHBondContact O-N 3.22Å; H220-A224 WeakPolarHBondContact O-CB 3.18Å; H220-A224 PolarHBondContact O-N 3.34Å; H220-V250 PolarHBondContact NE2-O 3.26Å
221	E	98.4	Very high	98.5	Very high	84 Å²	84	31.3 Å²	31.3	39%	0.393	18%	0.178	S	C	.	.	H	α-helix	trans	-62.7	-43.2	173.7	-177	-171.7	179.3	0	0	111	V216 G217 S218 Q223 A224 V225	V216-E221 HydrophobicContact CG1-CB 4.04Å; V216-E221 HydrophobicContact CG1-CG 4.01Å; G217-E221 PolarHBondContact N-OE2 2.85Å; S218-E221 PolarHBondContact O-N 3.38Å; S218-E221 VanDerWaalsContact OG-CB 3.32Å; S218-E221 WeakPolarHBondContact OG-CB 3.38Å; S218-E221 PolarHBondContact OG-N 2.81Å; S218-E221 VanDerWaalsContact OG-N 3.1Å; E221-Q223 PolarHBondContact O-N 2.97Å; E221-A224 WeakPolarHBondContact O-CB 3.42Å; E221-A224 PolarHBondContact O-N 2.91Å; E221-V225 WeakPolarHBondContact O-CG2 3.5Å; E221-V225 PolarHBondContact O-N 3.48Å
222	L	98.7	Very high	98.5	Very high	0 Å²	0	30.4 Å²	30.4	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-58.9	-47.8	174.4	176.8	59.4	0	0	0	111.5	L159 L166 L169 W177 I212 V216 S218 D219 A224 V225 L226	L159-L222 HydrophobicContact CD2-CD1 4.28Å; L166-L222 HydrophobicContact CD1-CB 3.91Å; L166-L222 HydrophobicContact CD1-CD2 3.74Å; L166-L222 HydrophobicContact CD1-CG 4.43Å; L169-L222 HydrophobicContact CD1-CD2 3.98Å; L169-L222 HydrophobicContact CD2-CD2 3.33Å; L169-L222 HydrophobicContact CG-CD2 4.32Å; W177-L222 HydrophobicContact CH2-CD2 4.48Å; W177-L222 HydrophobicContact CZ3-CD2 4.24Å; W177-L222 HydrophobicContact CZ3-CG 4.15Å; I212-L222 HydrophobicContact CD1-CD1 4.13Å; I212-L222 HydrophobicContact CG2-CD1 3.84Å; V216-L222 HydrophobicContact CG1-CB 3.88Å; S218-L222 PolarHBondContact O-N 2.94Å; D219-L222 PolarHBondContact O-N 2.88Å; L222-A224 VanDerWaalsContact C-N 3.28Å; L222-A224 PolarHBondContact O-N 3.44Å; L222-V225 PolarHBondContact O-N 2.7Å; L222-L226 VanDerWaalsContact O-CB 3.24Å; L222-L226 WeakPolarHBondContact O-CB 3.36Å; L222-L226 PolarHBondContact O-N 2.85Å
223	Q	98.6	Very high	98.5	Very high	46 Å²	46	30.2 Å²	30.2	22%	0.215	17%	0.172	C	C	.	.	H	α-helix	trans	-58.5	-42.9	177.8	-173	-179.7	22.4	0	0	110.8	W177 D219 H220 E221 L227 V250	W177-Q223 HydrophobicContact CD2-CB 4.12Å; W177-Q223 HydrophobicContact CD2-CG 3.72Å; W177-Q223 HydrophobicContact CE3-CB 3.87Å; W177-Q223 HydrophobicContact CE3-CG 3.84Å; W177-Q223 HydrophobicContact CG-CG 4.06Å; W177-Q223 HydrophobicContact CH2-CB 4.01Å; W177-Q223 HydrophobicContact CZ2-CB 4.23Å; W177-Q223 HydrophobicContact CZ3-CB 3.82Å; W177-Q223 HydrophobicContact CZ3-CG 4.32Å; D219-Q223 WeakPolarHBondContact O-CB 3.4Å; D219-Q223 PolarHBondContact O-N 3.25Å; H220-Q223 PolarHBondContact O-N 3.22Å; E221-Q223 PolarHBondContact O-N 2.97Å; Q223-L227 HydrophobicContact CG-CD1 3.94Å; Q223-L227 HydrophobicContact CG-CG 4.29Å; Q223-L227 VanDerWaalsContact O-CB 3.28Å; Q223-L227 WeakPolarHBondContact O-CB 3.36Å; Q223-L227 VanDerWaalsContact O-CG 3.22Å; Q223-L227 WeakPolarHBondContact O-CG 3.34Å; Q223-L227 PolarHBondContact O-N 3.49Å; Q223-V250 HydrophobicContact CG-CG1 4.27Å; Q223-V250 HydrophobicContact CG-CG2 4.25Å
224	A	98.7	Very high	98.5	Very high	1 Å²	1	27.3 Å²	27.3	1%	0.008	15%	0.151	C	C	.	.	H	α-helix	trans	-61.1	-50.4	177.6	0	0	0	0	0	112.4	H220 E221 L222 L227 T228 V250 E251 R260	H220-A224 WeakPolarHBondContact O-CB 3.18Å; H220-A224 PolarHBondContact O-N 3.34Å; E221-A224 WeakPolarHBondContact O-CB 3.42Å; E221-A224 PolarHBondContact O-N 2.91Å; L222-A224 VanDerWaalsContact C-N 3.28Å; L222-A224 PolarHBondContact O-N 3.44Å; A224-L227 PolarHBondContact O-N 3.43Å; A224-T228 PolarHBondContact O-N 3.22Å; A224-T228 PolarHBondContact O-OG1 3.03Å; A224-V250 HydrophobicContact CB-CG2 3.83Å; A224-E251 HydrophobicContact CB-CG 3.66Å; A224-R260 PolarHBondContact O-NH1 2.83Å
225	V	98.8	Very high	98.5	Very high	16 Å²	16	28.2 Å²	28.2	10%	0.097	16%	0.157	C	C	.	.	H	α-helix	trans	-65.5	-43.6	179.5	-178.2	0	0	0	0	111	V211 I212 E221 L222 L227 T228 C229	V211-V225 HydrophobicContact CG1-CG1 3.9Å; I212-V225 HydrophobicContact CG1-CG1 3.72Å; E221-V225 WeakPolarHBondContact O-CG2 3.5Å; E221-V225 PolarHBondContact O-N 3.48Å; L222-V225 PolarHBondContact O-N 2.7Å; V225-L227 PolarHBondContact O-N 2.76Å; V225-T228 WeakPolarHBondContact O-CB 3.47Å; V225-T228 PolarHBondContact O-N 2.62Å; V225-C229 PolarHBondContact O-N 2.91Å
226	L	98.9	Very high	98.6	Very high	0 Å²	0	28.9 Å²	28.9	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-61.6	-43.5	177.9	179.6	63.8	0	0	0	111.7	L159 P174 W177 L178 L204 C208 I212 L222 T228 C229 L230	L159-L226 HydrophobicContact CD1-CD1 4.18Å; L159-L226 HydrophobicContact CD1-CD2 4Å; P174-L226 HydrophobicContact CB-CD2 3.89Å; W177-L226 HydrophobicContact CE3-CD2 4Å; L178-L226 HydrophobicContact CD2-CD1 4.39Å; L178-L226 HydrophobicContact CD2-CD2 4.11Å; L178-L226 HydrophobicContact CD2-CG 4.11Å; L178-L226 HydrophobicContact CG-CD2 4.32Å; L204-L226 HydrophobicContact CD1-CD1 4.49Å; C208-L226 WeakPolarHBondContact SG-CD1 3.44Å; I212-L226 HydrophobicContact CD1-CB 4.49Å; I212-L226 HydrophobicContact CD1-CD1 4.35Å; L222-L226 VanDerWaalsContact O-CB 3.24Å; L222-L226 WeakPolarHBondContact O-CB 3.36Å; L222-L226 PolarHBondContact O-N 2.85Å; L226-T228 VanDerWaalsContact C-N 3.32Å; L226-C229 WeakPolarHBondContact O-CB 3.47Å; L226-C229 PolarHBondContact O-N 2.88Å; L226-L230 WeakPolarHBondContact O-CB 3.4Å; L226-L230 PolarHBondContact O-N 3.38Å
227	L	98.9	Very high	98.6	Very high	3 Å²	3	29.5 Å²	29.5	2%	0.016	16%	0.16	C	C	.	.	H	α-helix	trans	-70.6	-28.1	178.2	-70.6	-177.4	0	0	0	112.6	V181 Q223 A224 V225 L230 Y231 F248 V250	V181-L227 HydrophobicContact CG2-CD2 3.78Å; Q223-L227 HydrophobicContact CG-CD1 3.94Å; Q223-L227 HydrophobicContact CG-CG 4.29Å; Q223-L227 VanDerWaalsContact O-CB 3.28Å; Q223-L227 WeakPolarHBondContact O-CB 3.36Å; Q223-L227 VanDerWaalsContact O-CG 3.22Å; Q223-L227 WeakPolarHBondContact O-CG 3.34Å; Q223-L227 PolarHBondContact O-N 3.49Å; A224-L227 PolarHBondContact O-N 3.43Å; V225-L227 PolarHBondContact O-N 2.76Å; L227-L230 HydrophobicContact CD2-CD2 3.83Å; L227-L230 PolarHBondContact O-N 2.98Å; L227-Y231 WeakPolarHBondContact O-CB 3.38Å; L227-Y231 PolarHBondContact O-N 3.18Å; L227-F248 WeakPolarHBondContact CB-O 3.39Å; L227-V250 HydrophobicContact CD1-CG1 3.61Å; L227-V250 HydrophobicContact CD1-CG2 4.41Å
228	T	98.9	Very high	98.5	Very high	0 Å²	0	28.4 Å²	28.4	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-63.3	-47.7	166.7	-59.8	0	0	0	0	111.3	A224 V225 L226 L230 Y231 L232 F257 R260	A224-T228 PolarHBondContact O-N 3.22Å; A224-T228 PolarHBondContact O-OG1 3.03Å; V225-T228 WeakPolarHBondContact O-CB 3.47Å; V225-T228 PolarHBondContact O-N 2.62Å; L226-T228 VanDerWaalsContact C-N 3.32Å; T228-L230 VanDerWaalsContact C-N 3.29Å; T228-L230 PolarHBondContact O-N 3.34Å; T228-Y231 PolarHBondContact O-N 3.15Å; T228-L232 WeakPolarHBondContact O-CG 3.49Å; T228-L232 PolarHBondContact O-N 3.26Å; T228-L232 VanDerWaalsContact O-N 3.09Å; T228-F257 WeakPolarHBondContact OG1-CD2 3.36Å; T228-F257 WeakPolarHBondContact OG1-CE2 3.34Å; T228-R260 HydrophobicContact CG2-CB 4.12Å; T228-R260 HydrophobicContact CG2-CG 3.94Å; T228-R260 PolarHBondContact OG1-NH1 3.33Å
229	C	98.9	Very high	98.4	Very high	0 Å²	0	28.4 Å²	28.4	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-60.5	-39.4	174.8	-67.7	0	0	0	0	112	L204 L207 V225 L226 S233	L204-C229 HydrophobicContact CD1-CB 3.85Å; L207-C229 HydrophobicContact CB-CB 4.17Å; L207-C229 HydrophobicContact CD1-CB 4.3Å; L207-C229 WeakPolarHBondContact CD1-O 3.35Å; V225-C229 PolarHBondContact O-N 2.91Å; L226-C229 WeakPolarHBondContact O-CB 3.47Å; L226-C229 PolarHBondContact O-N 2.88Å; C229-S233 PolarHBondContact O-N 2.81Å; C229-S233 PolarHBondContact O-OG 3.02Å
230	L	98.9	Very high	98.4	Very high	0 Å²	0	28.5 Å²	28.5	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-63.8	-48.2	176.2	-173.9	64.7	0	0	0	111.1	L178 V181 F195 I196 L204 L226 L227 T228 L232 S233 Y234 F248	L178-L230 HydrophobicContact CD2-CB 4.22Å; L178-L230 HydrophobicContact CD2-CD1 3.89Å; L178-L230 HydrophobicContact CD2-CD2 3.65Å; L178-L230 HydrophobicContact CD2-CG 4.09Å; V181-L230 HydrophobicContact CB-CD2 3.99Å; V181-L230 HydrophobicContact CG1-CD2 3.91Å; V181-L230 HydrophobicContact CG2-CD2 4.29Å; F195-L230 HydrophobicContact CE1-CD1 4.27Å; I196-L230 HydrophobicContact CD1-CD1 4.33Å; L204-L230 HydrophobicContact CD1-CB 4.37Å; L204-L230 HydrophobicContact CD1-CD1 4.46Å; L204-L230 HydrophobicContact CD2-CD1 4.03Å; L226-L230 WeakPolarHBondContact O-CB 3.4Å; L226-L230 PolarHBondContact O-N 3.38Å; L227-L230 HydrophobicContact CD2-CD2 3.83Å; L227-L230 PolarHBondContact O-N 2.98Å; T228-L230 VanDerWaalsContact C-N 3.29Å; T228-L230 PolarHBondContact O-N 3.34Å; L230-L232 VanDerWaalsContact C-N 3.3Å; L230-L232 PolarHBondContact O-N 3.48Å; L230-S233 CarbonylContact O-C 3.58Å; L230-S233 WeakPolarHBondContact O-CA 3.3Å; L230-S233 VanDerWaalsContact O-CB 3.3Å; L230-S233 WeakPolarHBondContact O-CB 3.41Å; L230-S233 PolarHBondContact O-N 2.99Å; L230-Y234 HydrophobicContact CD1-CD2 3.95Å; L230-Y234 HydrophobicContact CD1-CE2 3.62Å; L230-Y234 HydrophobicContact CD2-CD2 4.48Å; L230-Y234 HydrophobicContact CD2-CE2 3.9Å; L230-Y234 HydrophobicContact CG-CD2 3.77Å; L230-Y234 HydrophobicContact CG-CE2 3.58Å; L230-Y234 WeakPolarHBondContact O-CD2 3.45Å; L230-Y234 PolarHBondContact O-N 3.48Å; L230-F248 HydrophobicContact CB-CD1 4.46Å; L230-F248 HydrophobicContact CB-CE1 4.46Å; L230-F248 HydrophobicContact CD2-CD1 4.24Å; L230-F248 HydrophobicContact CD2-CE1 3.96Å; L230-F248 HydrophobicContact CG-CD1 4.37Å; L230-F248 HydrophobicContact CG-CE1 3.96Å
231	Y	98.9	Very high	98.4	Very high	36 Å²	36	32.3 Å²	32.3	14%	0.141	17%	0.166	C	C	.	.	H	α-helix	trans	-56.4	-43.8	178.3	176.8	-105.1	0	0	0	112.3	L227 T228 S233 Y234 S235 F248 F257 W258	L227-Y231 WeakPolarHBondContact O-CB 3.38Å; L227-Y231 PolarHBondContact O-N 3.18Å; T228-Y231 PolarHBondContact O-N 3.15Å; Y231-S233 VanDerWaalsContact C-N 3.31Å; Y231-S233 PolarHBondContact O-N 3.44Å; Y231-Y234 PolarHBondContact O-N 2.98Å; Y231-S235 WeakPolarHBondContact O-CB 3.41Å; Y231-S235 PolarHBondContact O-N 2.91Å; Y231-S235 PolarHBondContact O-OG 2.79Å; Y231-F248 HydrophobicContact CD2-CB 4.41Å; Y231-F248 HydrophobicContact CD2-CD1 4.29Å; Y231-F248 AromaticContact CD2-CD2 3.59Å; Y231-F248 HydrophobicContact CD2-CD2 3.59Å; Y231-F248 HydrophobicContact CD2-CE1 4.45Å; Y231-F248 AromaticContact CD2-CE2 3.8Å; Y231-F248 HydrophobicContact CD2-CE2 3.8Å; Y231-F248 AromaticContact CD2-CG 3.84Å; Y231-F248 HydrophobicContact CD2-CG 3.84Å; Y231-F248 HydrophobicContact CD2-CZ 4.22Å; Y231-F248 HydrophobicContact CE2-CD2 4.37Å; Y231-F248 HydrophobicContact CE2-CE2 4.5Å; Y231-F248 HydrophobicContact CG-CD1 4.49Å; Y231-F248 HydrophobicContact CG-CD2 4.45Å; Y231-F248 HydrophobicContact CG-CG 4.27Å; Y231-F257 AromaticContact CD1-CE1 3.96Å; Y231-F257 HydrophobicContact CD1-CE1 3.96Å; Y231-F257 AromaticContact CD1-CZ 3.75Å; Y231-F257 HydrophobicContact CD1-CZ 3.75Å; Y231-F257 HydrophobicContact CE1-CE1 4.23Å; Y231-F257 HydrophobicContact CE1-CZ 4.43Å; Y231-F257 HydrophobicContact CG-CE1 4.39Å; Y231-F257 AromaticContact CG-CZ 3.79Å; Y231-F257 HydrophobicContact CG-CZ 3.79Å; Y231-W258 HydrophobicContact CE1-CH2 4.36Å; Y231-W258 AromaticContact CE1-CZ3 3.9Å; Y231-W258 HydrophobicContact CE1-CZ3 3.9Å
232	L	98.8	Very high	98.3	Very high	11 Å²	11	31.5 Å²	31.5	6%	0.058	17%	0.169	C	C	.	.	H	α-helix	trans	-65.3	-35.5	174.7	-67.6	176.1	0	0	0	112.2	T228 L230 S235 Y236 C261 V264 I265	T228-L232 WeakPolarHBondContact O-CG 3.49Å; T228-L232 PolarHBondContact O-N 3.26Å; T228-L232 VanDerWaalsContact O-N 3.09Å; L230-L232 VanDerWaalsContact C-N 3.3Å; L230-L232 PolarHBondContact O-N 3.48Å; L232-S235 PolarHBondContact O-N 3.34Å; L232-Y236 VanDerWaalsContact O-CB 3.29Å; L232-Y236 WeakPolarHBondContact O-CB 3.25Å; L232-Y236 PolarHBondContact O-N 3.49Å; L232-C261 HydrophobicContact CD2-CB 4.28Å; L232-V264 HydrophobicContact CD1-CB 3.58Å; L232-V264 HydrophobicContact CD1-CG1 3.38Å; L232-V264 HydrophobicContact CD1-CG2 4.49Å; L232-I265 HydrophobicContact CD1-CG1 4.28Å; L232-I265 HydrophobicContact CD2-CD1 3.79Å; L232-I265 HydrophobicContact CD2-CG1 3.85Å
233	S	98.8	Very high	98.3	Very high	0 Å²	0	32.3 Å²	32.3	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-65.1	-45.2	174.7	-54.8	0	0	0	0	111.7	F195 L207 C229 L230 Y231 S235 Y236 M237	F195-S233 VanDerWaalsContact CZ-C 3.48Å; F195-S233 WeakPolarHBondContact CZ-O 3.29Å; L207-S233 WeakPolarHBondContact CD1-OG 3.46Å; C229-S233 PolarHBondContact O-N 2.81Å; C229-S233 PolarHBondContact O-OG 3.02Å; L230-S233 CarbonylContact O-C 3.58Å; L230-S233 WeakPolarHBondContact O-CA 3.3Å; L230-S233 VanDerWaalsContact O-CB 3.3Å; L230-S233 WeakPolarHBondContact O-CB 3.41Å; L230-S233 PolarHBondContact O-N 2.99Å; Y231-S233 VanDerWaalsContact C-N 3.31Å; Y231-S233 PolarHBondContact O-N 3.44Å; S233-S235 VanDerWaalsContact C-N 3.34Å; S233-Y236 PolarHBondContact O-N 3.28Å; S233-M237 WeakPolarHBondContact O-CB 3.46Å; S233-M237 PolarHBondContact O-N 3.38Å
234	Y	98.7	Very high	98.3	Very high	0 Å²	0	31.2 Å²	31.2	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-59.7	-45.4	172.2	-86.4	-89.2	0	0	0	111.2	V181 D182 L185 F195 L230 Y231 Y236 G238 Y243 F248	V181-Y234 HydrophobicContact CG1-CE2 4.33Å; D182-Y234 VanDerWaalsContact CA-OH 3.26Å; D182-Y234 WeakPolarHBondContact CA-OH 3.44Å; D182-Y234 VanDerWaalsContact CB-OH 3.25Å; D182-Y234 WeakPolarHBondContact CB-OH 3.49Å; D182-Y234 VanDerWaalsContact CG-OH 3.3Å; D182-Y234 PolarHBondContact OD1-OH 2.92Å; L185-Y234 HydrophobicContact CD1-CD1 4.01Å; L185-Y234 HydrophobicContact CD1-CE1 3.44Å; L185-Y234 VanDerWaalsContact CD1-CE1 3.44Å; L185-Y234 HydrophobicContact CD1-CE2 4.31Å; F195-Y234 HydrophobicContact CB-CD1 3.88Å; F195-Y234 HydrophobicContact CB-CE1 3.15Å; F195-Y234 HydrophobicContact CB-CE2 4.34Å; F195-Y234 VanDerWaalsContact CB-CZ 3.43Å; F195-Y234 HydrophobicContact CD1-CD1 4.16Å; F195-Y234 AromaticContact CD1-CD2 3.91Å; F195-Y234 HydrophobicContact CD1-CD2 3.91Å; F195-Y234 AromaticContact CD1-CE1 3.86Å; F195-Y234 HydrophobicContact CD1-CE1 3.86Å; F195-Y234 AromaticContact CD1-CE2 3.58Å; F195-Y234 HydrophobicContact CD1-CE2 3.58Å; F195-Y234 HydrophobicContact CD1-CG 4.19Å; F195-Y234 AromaticContact CD1-CZ 3.55Å; F195-Y234 AromaticContact CD2-CD1 3.95Å; F195-Y234 HydrophobicContact CD2-CD1 3.95Å; F195-Y234 HydrophobicContact CD2-CE1 4.11Å; F195-Y234 HydrophobicContact CD2-CG 4.35Å; F195-Y234 HydrophobicContact CE1-CD2 4.1Å; F195-Y234 HydrophobicContact CE1-CE2 4.14Å; F195-Y234 HydrophobicContact CE1-CG 4.42Å; F195-Y234 AromaticContact CG-CD1 3.73Å; F195-Y234 HydrophobicContact CG-CD1 3.73Å; F195-Y234 HydrophobicContact CG-CD2 4.33Å; F195-Y234 AromaticContact CG-CE1 3.45Å; F195-Y234 HydrophobicContact CG-CE1 3.45Å; F195-Y234 VanDerWaalsContact CG-CE1 3.45Å; F195-Y234 HydrophobicContact CG-CE2 4.08Å; F195-Y234 HydrophobicContact CG-CG 4.17Å; F195-Y234 AromaticContact CG-CZ 3.63Å; L230-Y234 HydrophobicContact CD1-CD2 3.95Å; L230-Y234 HydrophobicContact CD1-CE2 3.62Å; L230-Y234 HydrophobicContact CD2-CD2 4.48Å; L230-Y234 HydrophobicContact CD2-CE2 3.9Å; L230-Y234 HydrophobicContact CG-CD2 3.77Å; L230-Y234 HydrophobicContact CG-CE2 3.58Å; L230-Y234 WeakPolarHBondContact O-CD2 3.45Å; L230-Y234 PolarHBondContact O-N 3.48Å; Y231-Y234 PolarHBondContact O-N 2.98Å; Y234-Y236 VanDerWaalsContact C-N 3.28Å; Y234-Y236 PolarHBondContact O-N 3.35Å; Y234-G238 WeakPolarHBondContact O-CA 3.47Å; Y234-G238 PolarHBondContact O-N 3.35Å; Y234-Y243 AromaticContact CD1-CD1 3.7Å; Y234-Y243 HydrophobicContact CD1-CD1 3.7Å; Y234-Y243 HydrophobicContact CD1-CD2 4.38Å; Y234-Y243 AromaticContact CD1-CE1 3.5Å; Y234-Y243 HydrophobicContact CD1-CE1 3.5Å; Y234-Y243 VanDerWaalsContact CD1-CE1 3.5Å; Y234-Y243 HydrophobicContact CD1-CE2 4.23Å; Y234-Y243 HydrophobicContact CD1-CG 4.13Å; Y234-Y243 AromaticContact CD1-CZ 3.78Å; Y234-Y243 HydrophobicContact CE1-CD1 4.4Å; Y234-Y243 HydrophobicContact CE1-CE1 4.15Å; Y234-Y243 HydrophobicContact CG-CD1 4.4Å; Y234-Y243 HydrophobicContact CG-CE1 4.48Å; Y234-Y243 HydrophobicContact CG-CG 4.42Å; Y234-Y243 WeakPolarHBondContact O-CE2 3.34Å; Y234-F248 AromaticContact CD2-CE1 3.56Å; Y234-F248 HydrophobicContact CD2-CE1 3.56Å; Y234-F248 AromaticContact CD2-CZ 3.68Å; Y234-F248 HydrophobicContact CD2-CZ 3.68Å; Y234-F248 AromaticContact CE2-CE1 3.87Å; Y234-F248 HydrophobicContact CE2-CE1 3.87Å; Y234-F248 HydrophobicContact CE2-CZ 4.06Å; Y234-F248 HydrophobicContact CG-CE1 4.31Å; Y234-F248 AromaticContact CG-CZ 4Å; Y234-F248 HydrophobicContact CG-CZ 4Å
235	S	98.5	Very high	98.3	Very high	66 Å²	66	33 Å²	33	46%	0.462	18%	0.178	S	C	.	.	H	α-helix	trans	-65	-30.1	-178.8	-56.4	0	0	0	0	113.3	Y231 L232 S233	Y231-S235 WeakPolarHBondContact O-CB 3.41Å; Y231-S235 PolarHBondContact O-N 2.91Å; Y231-S235 PolarHBondContact O-OG 2.79Å; L232-S235 PolarHBondContact O-N 3.34Å; S233-S235 VanDerWaalsContact C-N 3.34Å
236	Y	98.6	Very high	98.2	Very high	101 Å²	101	40.8 Å²	40.8	40%	0.396	21%	0.211	S	C	.	.	H	α-helix	trans	-97.4	-44	-176.3	-167.8	-91.4	0	0	0	113.8	F203 L232 S233 Y234 M272 L273	F203-Y236 AromaticContact CE2-CD1 3.82Å; F203-Y236 HydrophobicContact CE2-CD1 3.82Å; F203-Y236 HydrophobicContact CE2-CE1 4.06Å; F203-Y236 AromaticContact CZ-CD1 3.51Å; F203-Y236 HydrophobicContact CZ-CD1 3.51Å; F203-Y236 HydrophobicContact CZ-CE1 4.12Å; F203-Y236 HydrophobicContact CZ-CG 4.13Å; L232-Y236 VanDerWaalsContact O-CB 3.29Å; L232-Y236 WeakPolarHBondContact O-CB 3.25Å; L232-Y236 PolarHBondContact O-N 3.49Å; S233-Y236 PolarHBondContact O-N 3.28Å; Y234-Y236 VanDerWaalsContact C-N 3.28Å; Y234-Y236 PolarHBondContact O-N 3.35Å; Y236-M272 HydrophobicContact CD1-CE 4.14Å; Y236-M272 HydrophobicContact CD2-CE 3.62Å; Y236-M272 HydrophobicContact CE1-CB 4.2Å; Y236-M272 HydrophobicContact CE2-CB 4.41Å; Y236-M272 HydrophobicContact CE2-CE 4.32Å; Y236-M272 HydrophobicContact CG-CE 3.52Å; Y236-L273 WeakPolarHBondContact OH-CA 3.47Å
237	M	98.1	Very high	98.2	Very high	16 Å²	16	42 Å²	42	8%	0.079	22%	0.219	C	C	.	.	H	α-helix	trans	-102.9	-9.9	-174.6	-63.3	-66.2	-68.4	0	0	113.3	F195 F203 S233 N276	F195-M237 HydrophobicContact CE2-CB 3.86Å; F195-M237 HydrophobicContact CZ-CB 4.14Å; F203-M237 HydrophobicContact CB-CG 4.48Å; F203-M237 HydrophobicContact CD1-CG 3.85Å; F203-M237 HydrophobicContact CD2-CE 4.3Å; F203-M237 HydrophobicContact CD2-CG 3.69Å; F203-M237 HydrophobicContact CD2-SD 3.69Å; F203-M237 HydrophobicContact CE1-CG 3.91Å; F203-M237 HydrophobicContact CE2-CG 3.75Å; F203-M237 HydrophobicContact CE2-SD 3.68Å; F203-M237 HydrophobicContact CG-CG 3.74Å; F203-M237 HydrophobicContact CG-SD 4.32Å; F203-M237 HydrophobicContact CZ-CG 3.85Å; F203-M237 HydrophobicContact CZ-SD 4.29Å; S233-M237 WeakPolarHBondContact O-CB 3.46Å; S233-M237 PolarHBondContact O-N 3.38Å; M237-N276 WeakPolarHBondContact CE-OD1 3.41Å; M237-N276 PolarHBondContact SD-ND2 3.22Å
238	G	97.1	Very high	98.1	Very high	19 Å²	19	41.9 Å²	41.9	20%	0.196	22%	0.218	C	C	.	.			trans	-73.4	153.4	-177.9	0	0	0	0	0	112.7	Y234 Y243	Y234-G238 WeakPolarHBondContact O-CA 3.47Å; Y234-G238 PolarHBondContact O-N 3.35Å; G238-Y243 WeakPolarHBondContact CA-OH 3.24Å
239	N	95.8	Very high	98.1	Very high	49 Å²	49	43.7 Å²	43.7	26%	0.262	23%	0.228	S	C	.	.	S	Bend	trans	-85.1	-22.5	-178.8	-62.2	-32.5	0	0	0	113.1	Y243	N239-Y243 PolarHBondContact N-OH 2.92Å
240	E	97.3	Very high	98.1	Very high	54 Å²	54	45.8 Å²	45.8	25%	0.252	24%	0.24	S	C	.	.	S	Bend	trans	-80.7	145.9	179.4	-45.6	-58.8	155.7	0	0	111.1	W190 Q191 S242 Y243	W190-E240 WeakPolarHBondContact O-CG 3.31Å; Q191-E240 HydrophobicContact CB-CG 4.02Å; E240-S242 PolarHBondContact O-N 3.38Å; E240-Y243 HydrophobicContact CB-CE1 3.91Å; E240-Y243 HydrophobicContact CB-CE2 4.15Å; E240-Y243 WeakPolarHBondContact CB-OH 3.41Å; E240-Y243 HydrophobicContact CG-CE1 3.87Å; E240-Y243 WeakPolarHBondContact CG-OH 3.49Å; E240-Y243 PolarHBondContact N-OH 2.92Å; E240-Y243 VanDerWaalsContact N-OH 3.15Å
241	I	97.4	Very high	98	Very high	176 Å²	176	47.6 Å²	47.6	90%	0.903	25%	0.249	S	C	*	.	S	Bend	trans	-66.2	-18.5	-176.9	61.5	170.6	0	0	0	113.9
242	S	98	Very high	97.9	Very high	68 Å²	68	52 Å²	52	48%	0.476	29%	0.285	S	S	.	.			trans	-163.3	152.5	-179.6	64.7	0	0	0	0	111.4	E240	E240-S242 PolarHBondContact O-N 3.38Å
243	Y	98.5	Very high	97.7	Very high	17 Å²	17	54.4 Å²	54.4	7%	0.067	30%	0.302	C	S	.	.			trans	-125.8	143.6	173.6	-61.9	-87.3	0	0	0	110.6	L185 Y234 G238 N239 E240	L185-Y243 HydrophobicContact CD1-CD1 4.22Å; Y234-Y243 AromaticContact CD1-CD1 3.7Å; Y234-Y243 HydrophobicContact CD1-CD1 3.7Å; Y234-Y243 HydrophobicContact CD1-CD2 4.38Å; Y234-Y243 AromaticContact CD1-CE1 3.5Å; Y234-Y243 HydrophobicContact CD1-CE1 3.5Å; Y234-Y243 VanDerWaalsContact CD1-CE1 3.5Å; Y234-Y243 HydrophobicContact CD1-CE2 4.23Å; Y234-Y243 HydrophobicContact CD1-CG 4.13Å; Y234-Y243 AromaticContact CD1-CZ 3.78Å; Y234-Y243 HydrophobicContact CE1-CD1 4.4Å; Y234-Y243 HydrophobicContact CE1-CE1 4.15Å; Y234-Y243 HydrophobicContact CG-CD1 4.4Å; Y234-Y243 HydrophobicContact CG-CE1 4.48Å; Y234-Y243 HydrophobicContact CG-CG 4.42Å; Y234-Y243 WeakPolarHBondContact O-CE2 3.34Å; G238-Y243 WeakPolarHBondContact CA-OH 3.24Å; N239-Y243 PolarHBondContact N-OH 2.92Å; E240-Y243 HydrophobicContact CB-CE1 3.91Å; E240-Y243 HydrophobicContact CB-CE2 4.15Å; E240-Y243 WeakPolarHBondContact CB-OH 3.41Å; E240-Y243 HydrophobicContact CG-CE1 3.87Å; E240-Y243 WeakPolarHBondContact CG-OH 3.49Å; E240-Y243 PolarHBondContact N-OH 2.92Å; E240-Y243 VanDerWaalsContact N-OH 3.15Å
244	P	98.1	Very high	97.7	Very high	22 Å²	22	60.5 Å²	60.5	14%	0.143	33%	0.329	C	S	.	.			trans	-71	144.1	-179.4	32.1	-37.8	0	0	0	110.8	L185 W190 K246 P247 F248	L185-P244 HydrophobicContact CD2-CG 3.63Å; W190-P244 HydrophobicContact CD2-CB 4.31Å; W190-P244 HydrophobicContact CD2-CG 3.65Å; W190-P244 HydrophobicContact CE3-CG 4.21Å; W190-P244 HydrophobicContact CG-CG 3.85Å; W190-P244 HydrophobicContact CH2-CB 4.16Å; W190-P244 HydrophobicContact CZ2-CB 3.81Å; W190-P244 HydrophobicContact CZ2-CG 4.03Å; P244-K246 VanDerWaalsContact C-N 3.35Å; P244-K246 PolarHBondContact O-N 3.14Å; P244-P247 HydrophobicContact CG-CG 4.21Å; P244-P247 VanDerWaalsContact O-CD 3.28Å; P244-P247 WeakPolarHBondContact O-CD 3.23Å; P244-F248 WeakPolarHBondContact O-CD2 3.49Å; P244-F248 VanDerWaalsContact O-CE2 3.24Å; P244-F248 WeakPolarHBondContact O-CE2 3.26Å
245	L	98.1	Very high	97.6	Very high	38 Å²	38	67.6 Å²	67.6	20%	0.199	36%	0.362	C	S	.	.	S	Bend	trans	-66.4	-34.2	177.5	176.9	63.2	0	0	0	113.3	P247 F248 L249 F257 W258	L245-P247 VanDerWaalsContact C-CD 3.49Å; L245-F248 PolarHBondContact O-N 3.48Å; L245-L249 HydrophobicContact CD1-CB 4.3Å; L245-L249 HydrophobicContact CD2-CD2 4.24Å; L245-L249 HydrophobicContact CG-CB 4.13Å; L245-L249 PolarHBondContact O-N 2.86Å; L245-F257 HydrophobicContact CD1-CD1 3.65Å; L245-F257 HydrophobicContact CD1-CE1 3.21Å; L245-F257 HydrophobicContact CD1-CE2 4.2Å; L245-F257 HydrophobicContact CD1-CG 4.32Å; L245-F257 HydrophobicContact CD1-CZ 3.51Å; L245-W258 HydrophobicContact CD1-CH2 4.32Å; L245-W258 HydrophobicContact CD1-CZ2 4.29Å; L245-W258 HydrophobicContact CD2-CZ2 3.75Å; L245-W258 HydrophobicContact CG-CZ2 4.49Å
246	K	97.6	Very high	97.6	Very high	180 Å²	180	66 Å²	66	78%	0.783	35%	0.352	S	S	*	.	T	Hydrogen-bonded Turn	trans	-51.7	-42.8	-166.5	-176.2	176.4	-179.5	173.8	0	114.9	P244 F248	P244-K246 VanDerWaalsContact C-N 3.35Å; P244-K246 PolarHBondContact O-N 3.14Å; K246-F248 PolarHBondContact O-N 3.11Å
247	P	97.8	Very high	97.6	Very high	26 Å²	26	61.2 Å²	61.2	17%	0.169	33%	0.334	C	S	.	.	T	Hydrogen-bonded Turn	trans	-67.3	-21.5	178.8	-23.2	37.1	0	0	0	114.7	V181 L185 P244 L245	V181-P247 HydrophobicContact CG1-CB 4.01Å; V181-P247 HydrophobicContact CG2-CB 4.37Å; V181-P247 WeakPolarHBondContact CG2-O 3.42Å; L185-P247 HydrophobicContact CD2-CG 4.03Å; P244-P247 HydrophobicContact CG-CG 4.21Å; P244-P247 VanDerWaalsContact O-CD 3.28Å; P244-P247 WeakPolarHBondContact O-CD 3.23Å; L245-P247 VanDerWaalsContact C-CD 3.49Å
248	F	98.6	Very high	97.7	Very high	0 Å²	0	65.7 Å²	65.7	0%	0	35%	0.35	C	S	.	.	T	Hydrogen-bonded Turn	trans	-98.3	-17.5	-173.9	-54.2	-89.5	0	0	0	113	V181 L185 L227 L230 Y231 Y234 P244 L245 K246 F257	V181-F248 HydrophobicContact CG1-CD1 4.04Å; V181-F248 HydrophobicContact CG1-CE1 3.54Å; V181-F248 HydrophobicContact CG1-CE2 4.41Å; V181-F248 HydrophobicContact CG1-CZ 3.76Å; L185-F248 HydrophobicContact CD1-CE2 4.38Å; L185-F248 HydrophobicContact CD1-CZ 3.91Å; L227-F248 WeakPolarHBondContact CB-O 3.39Å; L230-F248 HydrophobicContact CB-CD1 4.46Å; L230-F248 HydrophobicContact CB-CE1 4.46Å; L230-F248 HydrophobicContact CD2-CD1 4.24Å; L230-F248 HydrophobicContact CD2-CE1 3.96Å; L230-F248 HydrophobicContact CG-CD1 4.37Å; L230-F248 HydrophobicContact CG-CE1 3.96Å; Y231-F248 HydrophobicContact CD2-CB 4.41Å; Y231-F248 HydrophobicContact CD2-CD1 4.29Å; Y231-F248 AromaticContact CD2-CD2 3.59Å; Y231-F248 HydrophobicContact CD2-CD2 3.59Å; Y231-F248 HydrophobicContact CD2-CE1 4.45Å; Y231-F248 AromaticContact CD2-CE2 3.8Å; Y231-F248 HydrophobicContact CD2-CE2 3.8Å; Y231-F248 AromaticContact CD2-CG 3.84Å; Y231-F248 HydrophobicContact CD2-CG 3.84Å; Y231-F248 HydrophobicContact CD2-CZ 4.22Å; Y231-F248 HydrophobicContact CE2-CD2 4.37Å; Y231-F248 HydrophobicContact CE2-CE2 4.5Å; Y231-F248 HydrophobicContact CG-CD1 4.49Å; Y231-F248 HydrophobicContact CG-CD2 4.45Å; Y231-F248 HydrophobicContact CG-CG 4.27Å; Y234-F248 AromaticContact CD2-CE1 3.56Å; Y234-F248 HydrophobicContact CD2-CE1 3.56Å; Y234-F248 AromaticContact CD2-CZ 3.68Å; Y234-F248 HydrophobicContact CD2-CZ 3.68Å; Y234-F248 AromaticContact CE2-CE1 3.87Å; Y234-F248 HydrophobicContact CE2-CE1 3.87Å; Y234-F248 HydrophobicContact CE2-CZ 4.06Å; Y234-F248 HydrophobicContact CG-CE1 4.31Å; Y234-F248 AromaticContact CG-CZ 4Å; Y234-F248 HydrophobicContact CG-CZ 4Å; P244-F248 WeakPolarHBondContact O-CD2 3.49Å; P244-F248 VanDerWaalsContact O-CE2 3.24Å; P244-F248 WeakPolarHBondContact O-CE2 3.26Å; L245-F248 PolarHBondContact O-N 3.48Å; K246-F248 PolarHBondContact O-N 3.11Å; F248-F257 HydrophobicContact CB-CE2 4.24Å; F248-F257 HydrophobicContact CB-CZ 4.3Å
249	L	98.4	Very high	97.7	Very high	38 Å²	38	69.7 Å²	69.7	20%	0.199	37%	0.367	C	S	.	.			trans	-91.9	107.2	-174.9	-175.5	71.5	0	0	0	111	L245 E251 K254 F257	L245-L249 HydrophobicContact CD1-CB 4.3Å; L245-L249 HydrophobicContact CD2-CD2 4.24Å; L245-L249 HydrophobicContact CG-CB 4.13Å; L245-L249 PolarHBondContact O-N 2.86Å; L249-E251 HydrophobicContact CD1-CB 4.45Å; L249-K254 HydrophobicContact CD1-CG 4.47Å; L249-K254 HydrophobicContact CD2-CD 4.25Å; L249-K254 HydrophobicContact CD2-CG 3.69Å; L249-F257 HydrophobicContact CD1-CB 3.88Å; L249-F257 HydrophobicContact CD1-CD2 4.2Å; L249-F257 HydrophobicContact CD1-CG 4.09Å
250	V	98.1	Very high	97.9	Very high	44 Å²	44	69.6 Å²	69.6	27%	0.267	36%	0.363	S	S	.	.			trans	-107.3	-3.3	174.1	-64.5	0	0	0	0	113.2	H220 Q223 A224 L227	H220-V250 PolarHBondContact NE2-O 3.26Å; Q223-V250 HydrophobicContact CG-CG1 4.27Å; Q223-V250 HydrophobicContact CG-CG2 4.25Å; A224-V250 HydrophobicContact CB-CG2 3.83Å; L227-V250 HydrophobicContact CD1-CG1 3.61Å; L227-V250 HydrophobicContact CD1-CG2 4.41Å
251	E	97	Very high	97.9	Very high	38 Å²	38	67.3 Å²	67.3	18%	0.178	35%	0.352	C	S	.	.			trans	-98.4	148.5	-178.1	-64	171.8	99.8	0	0	111.3	A224 L249 R260	A224-E251 HydrophobicContact CB-CG 3.66Å; L249-E251 HydrophobicContact CD1-CB 4.45Å; E251-R260 VanDerWaalsContact CD-NH2 3.28Å; E251-R260 IonicContact OE1-CZ 3.77Å; E251-R260 IonicContact OE1-NH1 3.39Å; E251-R260 IonicContact OE1-NH2 2.58Å; E251-R260 PolarHBondContact OE1-NH2 3.49Å; E251-R260 IonicContact OE2-CZ 3.8Å; E251-R260 IonicContact OE2-NH1 3.79Å; E251-R260 PolarHBondContact OE2-NH1 3.41Å; E251-R260 IonicContact OE2-NH2 2.97Å; E251-R260 PolarHBondContact OE2-NH2 3.13Å; E251-R260 VanDerWaalsContact OE2-NH2 3.15Å
252	S	96	Very high	98	Very high	130 Å²	130	64.4 Å²	64.4	91%	0.909	34%	0.338	S	S	*	.	S	Bend	trans	-72.7	-34.8	171.8	51.7	0	0	0	0	112.1	K254	S252-K254 PolarHBondContact O-N 2.87Å
253	C	96.2	Very high	98	Very high	60 Å²	60	64.9 Å²	64.9	41%	0.405	34%	0.342	S	S	.	.			trans	-86.2	103.2	178	-172.9	0	0	0	0	111	E255 A256	C253-E255 VanDerWaalsContact C-N 3.32Å; C253-E255 PolarHBondContact O-N 3.29Å; C253-A256 HydrophobicContact CB-CB 4.13Å
254	K	97.4	Very high	98	Very high	129 Å²	129	64.3 Å²	64.3	56%	0.561	34%	0.34	S	S	*	.	H	α-helix	trans	-66.5	-32.2	176.7	-72.4	-177.4	-179.2	178.6	0	113.3	L249 S252 A256 F257 W258	L249-K254 HydrophobicContact CD1-CG 4.47Å; L249-K254 HydrophobicContact CD2-CD 4.25Å; L249-K254 HydrophobicContact CD2-CG 3.69Å; S252-K254 PolarHBondContact O-N 2.87Å; K254-A256 VanDerWaalsContact C-N 3.34Å; K254-F257 WeakPolarHBondContact O-CB 3.34Å; K254-F257 PolarHBondContact O-N 2.99Å; K254-W258 PolarHBondContact O-N 3.3Å
255	E	98.2	Very high	98.1	Very high	149 Å²	149	66.8 Å²	66.8	70%	0.696	35%	0.351	S	S	*	.	H	α-helix	trans	-63.3	-42.9	-179.5	-66.3	177.3	178.3	0	0	110.7	C253 F257 W258 D259	C253-E255 VanDerWaalsContact C-N 3.32Å; C253-E255 PolarHBondContact O-N 3.29Å; E255-F257 VanDerWaalsContact C-N 3.27Å; E255-F257 PolarHBondContact O-N 2.97Å; E255-W258 PolarHBondContact O-N 3.41Å; E255-D259 PolarHBondContact O-N 3.31Å
256	A	98.1	Very high	98.1	Very high	32 Å²	32	71.6 Å²	71.6	26%	0.264	38%	0.377	S	S	.	.	H	α-helix	trans	-57.5	-37.7	176	0	0	0	0	0	113.1	C253 K254 R260	C253-A256 HydrophobicContact CB-CB 4.13Å; K254-A256 VanDerWaalsContact C-N 3.34Å; A256-R260 VanDerWaalsContact O-CB 3.31Å; A256-R260 WeakPolarHBondContact O-CB 3.47Å; A256-R260 PolarHBondContact O-N 3.45Å
257	F	98.7	Very high	98.2	Very high	1 Å²	1	68 Å²	68	0%	0.004	37%	0.366	C	S	.	.	H	α-helix	trans	-63.4	-43.7	174.9	177.6	-86.3	0	0	0	111.8	T228 Y231 L245 F248 L249 K254 E255 R260 C261	T228-F257 WeakPolarHBondContact OG1-CD2 3.36Å; T228-F257 WeakPolarHBondContact OG1-CE2 3.34Å; Y231-F257 AromaticContact CD1-CE1 3.96Å; Y231-F257 HydrophobicContact CD1-CE1 3.96Å; Y231-F257 AromaticContact CD1-CZ 3.75Å; Y231-F257 HydrophobicContact CD1-CZ 3.75Å; Y231-F257 HydrophobicContact CE1-CE1 4.23Å; Y231-F257 HydrophobicContact CE1-CZ 4.43Å; Y231-F257 HydrophobicContact CG-CE1 4.39Å; Y231-F257 AromaticContact CG-CZ 3.79Å; Y231-F257 HydrophobicContact CG-CZ 3.79Å; L245-F257 HydrophobicContact CD1-CD1 3.65Å; L245-F257 HydrophobicContact CD1-CE1 3.21Å; L245-F257 HydrophobicContact CD1-CE2 4.2Å; L245-F257 HydrophobicContact CD1-CG 4.32Å; L245-F257 HydrophobicContact CD1-CZ 3.51Å; F248-F257 HydrophobicContact CB-CE2 4.24Å; F248-F257 HydrophobicContact CB-CZ 4.3Å; L249-F257 HydrophobicContact CD1-CB 3.88Å; L249-F257 HydrophobicContact CD1-CD2 4.2Å; L249-F257 HydrophobicContact CD1-CG 4.09Å; K254-F257 WeakPolarHBondContact O-CB 3.34Å; K254-F257 PolarHBondContact O-N 2.99Å; E255-F257 VanDerWaalsContact C-N 3.27Å; E255-F257 PolarHBondContact O-N 2.97Å; F257-R260 PolarHBondContact O-N 2.94Å; F257-C261 WeakPolarHBondContact CE1-SG 3.33Å; F257-C261 PolarHBondContact O-N 2.97Å; F257-C261 PolarHBondContact O-SG 3.23Å
258	W	98.7	Very high	98.2	Very high	109 Å²	109	66.8 Å²	66.8	41%	0.413	36%	0.358	S	S	.	.	H	α-helix	trans	-72.5	-40.4	-179.4	-66.1	123.6	0	0	0	112.7	Y231 L245 K254 E255 R260 C261 L262	Y231-W258 HydrophobicContact CE1-CH2 4.36Å; Y231-W258 AromaticContact CE1-CZ3 3.9Å; Y231-W258 HydrophobicContact CE1-CZ3 3.9Å; L245-W258 HydrophobicContact CD1-CH2 4.32Å; L245-W258 HydrophobicContact CD1-CZ2 4.29Å; L245-W258 HydrophobicContact CD2-CZ2 3.75Å; L245-W258 HydrophobicContact CG-CZ2 4.49Å; K254-W258 PolarHBondContact O-N 3.3Å; E255-W258 PolarHBondContact O-N 3.41Å; W258-R260 VanDerWaalsContact C-N 3.28Å; W258-R260 PolarHBondContact O-N 3.37Å; W258-C261 HydrophobicContact CE3-CB 4.47Å; W258-C261 WeakPolarHBondContact O-CB 3.46Å; W258-C261 PolarHBondContact O-N 3.13Å; W258-C261 VanDerWaalsContact O-N 3.1Å; W258-L262 PolarHBondContact O-N 3.04Å
259	D	98.7	Very high	98.2	Very high	104 Å²	104	69.7 Å²	69.7	56%	0.556	38%	0.378	S	S	*	.	H	α-helix	trans	-58.9	-43.2	173.1	-72	-27.7	0	0	0	110.8	E255 C261 L262 S263	E255-D259 PolarHBondContact O-N 3.31Å; D259-C261 PolarHBondContact O-N 3.15Å; D259-L262 PolarHBondContact O-N 2.97Å; D259-S263 WeakPolarHBondContact O-CB 3.43Å; D259-S263 PolarHBondContact O-N 3.1Å
260	R	98.6	Very high	98.2	Very high	47 Å²	47	72 Å²	72	18%	0.177	40%	0.397	C	S	.	.	H	α-helix	trans	-63.2	-40.9	174.3	-163.5	-173.9	-56.1	124.5	5.4	111.7	A224 T228 E251 A256 F257 W258 L262 S263 V264	A224-R260 PolarHBondContact O-NH1 2.83Å; T228-R260 HydrophobicContact CG2-CB 4.12Å; T228-R260 HydrophobicContact CG2-CG 3.94Å; T228-R260 PolarHBondContact OG1-NH1 3.33Å; E251-R260 VanDerWaalsContact CD-NH2 3.28Å; E251-R260 IonicContact OE1-CZ 3.77Å; E251-R260 IonicContact OE1-NH1 3.39Å; E251-R260 IonicContact OE1-NH2 2.58Å; E251-R260 PolarHBondContact OE1-NH2 3.49Å; E251-R260 IonicContact OE2-CZ 3.8Å; E251-R260 IonicContact OE2-NH1 3.79Å; E251-R260 PolarHBondContact OE2-NH1 3.41Å; E251-R260 IonicContact OE2-NH2 2.97Å; E251-R260 PolarHBondContact OE2-NH2 3.13Å; E251-R260 VanDerWaalsContact OE2-NH2 3.15Å; A256-R260 VanDerWaalsContact O-CB 3.31Å; A256-R260 WeakPolarHBondContact O-CB 3.47Å; A256-R260 PolarHBondContact O-N 3.45Å; F257-R260 PolarHBondContact O-N 2.94Å; W258-R260 VanDerWaalsContact C-N 3.28Å; W258-R260 PolarHBondContact O-N 3.37Å; R260-L262 PolarHBondContact O-N 2.83Å; R260-S263 PolarHBondContact O-N 3.46Å; R260-V264 HydrophobicContact CG-CG2 4.42Å; R260-V264 WeakPolarHBondContact O-CB 3.42Å; R260-V264 VanDerWaalsContact O-CG2 3.25Å; R260-V264 WeakPolarHBondContact O-CG2 3.49Å; R260-V264 PolarHBondContact O-N 2.87Å
261	C	98.8	Very high	98.2	Very high	5 Å²	5	73.1 Å²	73.1	3%	0.034	40%	0.399	C	S	.	.	H	α-helix	trans	-57.3	-50.3	174.7	-71.6	0	0	0	0	111.6	L232 F257 W258 D259 S263 V264 I265	L232-C261 HydrophobicContact CD2-CB 4.28Å; F257-C261 WeakPolarHBondContact CE1-SG 3.33Å; F257-C261 PolarHBondContact O-N 2.97Å; F257-C261 PolarHBondContact O-SG 3.23Å; W258-C261 HydrophobicContact CE3-CB 4.47Å; W258-C261 WeakPolarHBondContact O-CB 3.46Å; W258-C261 PolarHBondContact O-N 3.13Å; W258-C261 VanDerWaalsContact O-N 3.1Å; D259-C261 PolarHBondContact O-N 3.15Å; C261-S263 PolarHBondContact O-N 3.36Å; C261-V264 PolarHBondContact O-N 3.34Å; C261-I265 VanDerWaalsContact O-CG1 3.26Å; C261-I265 WeakPolarHBondContact O-CG1 3.35Å; C261-I265 PolarHBondContact O-N 2.94Å
262	L	98.7	Very high	98.3	Very high	116 Å²	116	71.7 Å²	71.7	61%	0.607	39%	0.392	S	S	*	.	H	α-helix	trans	-63.7	-41.6	-179.8	-66	177.9	0	0	0	111.8	W258 D259 R260 I265 N266	W258-L262 PolarHBondContact O-N 3.04Å; D259-L262 PolarHBondContact O-N 2.97Å; R260-L262 PolarHBondContact O-N 2.83Å; L262-I265 PolarHBondContact O-N 3.05Å; L262-N266 WeakPolarHBondContact O-CB 3.48Å; L262-N266 PolarHBondContact O-N 2.98Å
263	S	98.8	Very high	98.4	Very high	78 Å²	78	70.7 Å²	70.7	55%	0.545	38%	0.376	S	S	.	.	H	α-helix	trans	-59.2	-47.4	175.3	-177.6	0	0	0	0	111.9	D259 R260 C261 N266 L267	D259-S263 WeakPolarHBondContact O-CB 3.43Å; D259-S263 PolarHBondContact O-N 3.1Å; R260-S263 PolarHBondContact O-N 3.46Å; C261-S263 PolarHBondContact O-N 3.36Å; S263-N266 PolarHBondContact O-N 2.76Å; S263-L267 WeakPolarHBondContact O-CB 3.46Å; S263-L267 PolarHBondContact O-N 3.44Å
264	V	98.7	Very high	98.5	Very high	4 Å²	4	71.4 Å²	71.4	2%	0.024	37%	0.373	C	S	.	.	H	α-helix	trans	-66.1	-41.5	178.3	175.2	0	0	0	0	111.5	V211 L232 R260 C261 N266 L267 M268	V211-V264 HydrophobicContact CB-CG2 4.39Å; V211-V264 HydrophobicContact CG1-CG2 3.54Å; V211-V264 HydrophobicContact CG2-CB 4.37Å; V211-V264 HydrophobicContact CG2-CG1 3.76Å; V211-V264 HydrophobicContact CG2-CG2 3.86Å; L232-V264 HydrophobicContact CD1-CB 3.58Å; L232-V264 HydrophobicContact CD1-CG1 3.38Å; L232-V264 HydrophobicContact CD1-CG2 4.49Å; R260-V264 HydrophobicContact CG-CG2 4.42Å; R260-V264 WeakPolarHBondContact O-CB 3.42Å; R260-V264 VanDerWaalsContact O-CG2 3.25Å; R260-V264 WeakPolarHBondContact O-CG2 3.49Å; R260-V264 PolarHBondContact O-N 2.87Å; C261-V264 PolarHBondContact O-N 3.34Å; V264-N266 VanDerWaalsContact C-N 3.34Å; V264-N266 PolarHBondContact O-N 3.14Å; V264-L267 PolarHBondContact O-N 2.93Å; V264-M268 HydrophobicContact CG1-CB 4.37Å; V264-M268 HydrophobicContact CG1-CG 4.01Å; V264-M268 VanDerWaalsContact O-CB 3.23Å; V264-M268 WeakPolarHBondContact O-CB 3.18Å; V264-M268 WeakPolarHBondContact O-CG 3.21Å; V264-M268 PolarHBondContact O-N 3.25Å
265	I	98.8	Very high	98.5	Very high	75 Å²	75	65.4 Å²	65.4	39%	0.385	35%	0.347	S	S	.	.	H	α-helix	trans	-60.8	-45.7	175.9	-70.3	165	0	0	0	110.5	L232 C261 L262 L267 M268 S269	L232-I265 HydrophobicContact CD1-CG1 4.28Å; L232-I265 HydrophobicContact CD2-CD1 3.79Å; L232-I265 HydrophobicContact CD2-CG1 3.85Å; C261-I265 VanDerWaalsContact O-CG1 3.26Å; C261-I265 WeakPolarHBondContact O-CG1 3.35Å; C261-I265 PolarHBondContact O-N 2.94Å; L262-I265 PolarHBondContact O-N 3.05Å; I265-L267 VanDerWaalsContact C-N 3.29Å; I265-L267 PolarHBondContact O-N 3.49Å; I265-M268 PolarHBondContact O-N 2.95Å; I265-S269 WeakPolarHBondContact O-CB 3.44Å; I265-S269 PolarHBondContact O-N 3.16Å; I265-S269 PolarHBondContact O-OG 3.29Å
266	N	98.7	Very high	98.4	Very high	139 Å²	139	60.6 Å²	60.6	74%	0.743	33%	0.326	S	S	*	.	H	α-helix	trans	-59.9	-40.3	178.3	-175.3	67.2	0	0	0	111.8	L262 S263 V264	L262-N266 WeakPolarHBondContact O-CB 3.48Å; L262-N266 PolarHBondContact O-N 2.98Å; S263-N266 PolarHBondContact O-N 2.76Å; V264-N266 VanDerWaalsContact C-N 3.34Å; V264-N266 PolarHBondContact O-N 3.14Å
267	L	98.7	Very high	98.3	Very high	104 Å²	104	62.7 Å²	62.7	55%	0.545	34%	0.344	S	S	.	.	H	α-helix	trans	-76	-40.8	179.4	-177.4	64	0	0	0	113.5	V211 S263 V264 I265	V211-L267 HydrophobicContact CG2-CD2 4.49Å; S263-L267 WeakPolarHBondContact O-CB 3.46Å; S263-L267 PolarHBondContact O-N 3.44Å; V264-L267 PolarHBondContact O-N 2.93Å; I265-L267 VanDerWaalsContact C-N 3.29Å; I265-L267 PolarHBondContact O-N 3.49Å
268	M	98.7	Very high	98.2	Very high	1 Å²	1	65.2 Å²	65.2	1%	0.005	36%	0.357	C	S	.	.	H	α-helix	trans	-109.3	-12.5	-161.9	-60.4	-54.8	-63.5	0	0	114.8	M206 L207 D210 V211 V264 I265 S270 K271 M272	M206-M268 WeakPolarHBondContact O-CE 3.49Å; M206-M268 HydrophobicContact SD-CE 3.25Å; M206-M268 WeakPolarHBondContact SD-CE 3.38Å; L207-M268 HydrophobicContact CD2-CB 3.71Å; L207-M268 HydrophobicContact CD2-CE 4.11Å; L207-M268 HydrophobicContact CD2-CG 3.94Å; D210-M268 HydrophobicContact CB-CE 3.82Å; D210-M268 HydrophobicContact CB-SD 3.6Å; D210-M268 WeakPolarHBondContact OD2-CE 3.31Å; V211-M268 HydrophobicContact CG2-CG 3.85Å; V211-M268 HydrophobicContact CG2-SD 4.36Å; V264-M268 HydrophobicContact CG1-CB 4.37Å; V264-M268 HydrophobicContact CG1-CG 4.01Å; V264-M268 VanDerWaalsContact O-CB 3.23Å; V264-M268 WeakPolarHBondContact O-CB 3.18Å; V264-M268 WeakPolarHBondContact O-CG 3.21Å; V264-M268 PolarHBondContact O-N 3.25Å; I265-M268 PolarHBondContact O-N 2.95Å; M268-S270 VanDerWaalsContact C-N 3.26Å; M268-S270 PolarHBondContact O-N 3.06Å; M268-S270 VanDerWaalsContact O-N 3.13Å; M268-K271 HydrophobicContact CE-CB 4.12Å; M268-K271 HydrophobicContact CE-CD 3.66Å; M268-K271 PolarHBondContact O-N 3.31Å; M268-K271 HydrophobicContact SD-CD 4.37Å; M268-M272 HydrophobicContact CB-CG 4.23Å; M268-M272 HydrophobicContact CB-SD 4.1Å; M268-M272 VanDerWaalsContact O-CG 3.31Å; M268-M272 WeakPolarHBondContact O-CG 3.45Å; M268-M272 PolarHBondContact O-N 3.47Å
269	S	98.4	Very high	98	Very high	61 Å²	61	61.7 Å²	61.7	43%	0.427	35%	0.349	S	S	.	.	H	α-helix	trans	-50	-42.4	-175.5	51.4	0	0	0	0	113.9	I265 M272 L273	I265-S269 WeakPolarHBondContact O-CB 3.44Å; I265-S269 PolarHBondContact O-N 3.16Å; I265-S269 PolarHBondContact O-OG 3.29Å; S269-M272 PolarHBondContact O-N 3.05Å; S269-L273 PolarHBondContact O-N 3.36Å; S269-L273 VanDerWaalsContact O-N 3.15Å
270	S	98.6	Very high	97.9	Very high	85 Å²	85	63.6 Å²	63.6	59%	0.594	35%	0.354	S	S	*	.	H	α-helix	trans	-62.8	-46.5	176.5	-179.4	0	0	0	0	112.5	M268 L273 Q274	M268-S270 VanDerWaalsContact C-N 3.26Å; M268-S270 PolarHBondContact O-N 3.06Å; M268-S270 VanDerWaalsContact O-N 3.13Å; S270-L273 PolarHBondContact O-N 3.08Å; S270-Q274 WeakPolarHBondContact O-CB 3.1Å; S270-Q274 PolarHBondContact O-N 3.2Å
271	K	98.5	Very high	97.9	Very high	69 Å²	69	62.2 Å²	62.2	30%	0.3	35%	0.348	S	S	.	.	H	α-helix	trans	-69.5	-34.1	178.7	-70.4	176.1	174.2	172.2	0	112.6	M206 D210 M268 L273 Q274 I275 Y281	M206-K271 HydrophobicContact CE-CB 4.25Å; M206-K271 HydrophobicContact SD-CB 3.64Å; M206-K271 HydrophobicContact SD-CD 4.42Å; D210-K271 IonicContact OD1-NZ 4Å; D210-K271 WeakPolarHBondContact OD2-CD 3.48Å; D210-K271 IonicContact OD2-NZ 3.92Å; D210-K271 PolarHBondContact OD2-NZ 3.11Å; M268-K271 HydrophobicContact CE-CB 4.12Å; M268-K271 HydrophobicContact CE-CD 3.66Å; M268-K271 PolarHBondContact O-N 3.31Å; M268-K271 HydrophobicContact SD-CD 4.37Å; K271-L273 VanDerWaalsContact C-N 3.31Å; K271-L273 PolarHBondContact O-N 2.88Å; K271-Q274 PolarHBondContact O-N 3.37Å; K271-I275 WeakPolarHBondContact O-CB 3.29Å; K271-I275 WeakPolarHBondContact O-CG2 3.11Å; K271-I275 PolarHBondContact O-N 2.8Å; K271-Y281 HydrophobicContact CB-CE1 4.47Å
272	M	98.5	Very high	97.8	Very high	8 Å²	8	62.8 Å²	62.8	4%	0.039	35%	0.35	C	S	.	.	H	α-helix	trans	-62.1	-38.6	174.5	-68.7	170.8	71.9	0	0	111.7	F203 M206 L207 Y236 M268 S269 I275 N276	F203-M272 HydrophobicContact CE1-CE 4.13Å; F203-M272 HydrophobicContact CE1-CG 4.42Å; F203-M272 HydrophobicContact CE2-CB 4.15Å; F203-M272 HydrophobicContact CE2-CG 4.31Å; F203-M272 HydrophobicContact CZ-CB 3.87Å; F203-M272 HydrophobicContact CZ-CE 3.72Å; F203-M272 HydrophobicContact CZ-CG 3.68Å; M206-M272 HydrophobicContact CE-CB 4.46Å; M206-M272 HydrophobicContact CE-CG 3.95Å; L207-M272 HydrophobicContact CD2-CG 3.77Å; L207-M272 HydrophobicContact CD2-SD 4.01Å; Y236-M272 HydrophobicContact CD1-CE 4.14Å; Y236-M272 HydrophobicContact CD2-CE 3.62Å; Y236-M272 HydrophobicContact CE1-CB 4.2Å; Y236-M272 HydrophobicContact CE2-CB 4.41Å; Y236-M272 HydrophobicContact CE2-CE 4.32Å; Y236-M272 HydrophobicContact CG-CE 3.52Å; M268-M272 HydrophobicContact CB-CG 4.23Å; M268-M272 HydrophobicContact CB-SD 4.1Å; M268-M272 VanDerWaalsContact O-CG 3.31Å; M268-M272 WeakPolarHBondContact O-CG 3.45Å; M268-M272 PolarHBondContact O-N 3.47Å; S269-M272 PolarHBondContact O-N 3.05Å; M272-I275 WeakPolarHBondContact O-CG2 3.45Å; M272-N276 PolarHBondContact O-ND2 3.46Å
273	L	98.5	Very high	97.7	Very high	108 Å²	108	59.8 Å²	59.8	57%	0.565	34%	0.337	S	S	*	.	H	α-helix	trans	-73.7	-46.3	171.8	-178.2	62.1	0	0	0	111.5	Y236 S269 S270 K271 I275 N276 A277	Y236-L273 WeakPolarHBondContact OH-CA 3.47Å; S269-L273 PolarHBondContact O-N 3.36Å; S269-L273 VanDerWaalsContact O-N 3.15Å; S270-L273 PolarHBondContact O-N 3.08Å; K271-L273 VanDerWaalsContact C-N 3.31Å; K271-L273 PolarHBondContact O-N 2.88Å; L273-I275 VanDerWaalsContact C-N 3.32Å; L273-I275 PolarHBondContact O-N 3.12Å; L273-N276 PolarHBondContact O-N 3.36Å; L273-N276 VanDerWaalsContact O-N 3.08Å; L273-A277 PolarHBondContact O-N 2.88Å
274	Q	98.3	Very high	97.6	Very high	76 Å²	76	61.2 Å²	61.2	36%	0.355	34%	0.335	S	S	.	.	H	α-helix	trans	-57.8	-42.3	-177.1	-172.4	-176.5	6.3	0	0	112.2	S270 K271 N276 A277 D278 Y281	S270-Q274 WeakPolarHBondContact O-CB 3.1Å; S270-Q274 PolarHBondContact O-N 3.2Å; K271-Q274 PolarHBondContact O-N 3.37Å; Q274-N276 PolarHBondContact O-N 3.24Å; Q274-A277 PolarHBondContact O-N 3.32Å; Q274-A277 VanDerWaalsContact O-N 3.12Å; Q274-D278 HydrophobicContact CG-CB 4.33Å; Q274-D278 WeakPolarHBondContact O-CB 3.33Å; Q274-D278 PolarHBondContact O-N 2.92Å; Q274-Y281 HydrophobicContact CB-CD1 4.11Å; Q274-Y281 HydrophobicContact CB-CE1 4.3Å; Q274-Y281 HydrophobicContact CG-CD1 3.74Å; Q274-Y281 HydrophobicContact CG-CE1 4.27Å; Q274-Y281 HydrophobicContact CG-CG 4.24Å
275	I	97.8	Very high	97.6	Very high	3 Å²	3	61 Å²	61	2%	0.015	33%	0.334	C	S	.	.	H	α-helix	trans	-64.9	-22.6	-179.3	-159	173.4	0	0	0	113.2	V202 F203 M206 K271 M272 L273 Y281 F282 V285	V202-I275 HydrophobicContact CG1-CD1 4.33Å; F203-I275 HydrophobicContact CD2-CG2 3.58Å; F203-I275 HydrophobicContact CE2-CG2 3.72Å; M206-I275 HydrophobicContact CB-CD1 4.02Å; M206-I275 HydrophobicContact CE-CG2 4.05Å; M206-I275 HydrophobicContact CG-CD1 4.14Å; K271-I275 WeakPolarHBondContact O-CB 3.29Å; K271-I275 WeakPolarHBondContact O-CG2 3.11Å; K271-I275 PolarHBondContact O-N 2.8Å; M272-I275 WeakPolarHBondContact O-CG2 3.45Å; L273-I275 VanDerWaalsContact C-N 3.32Å; L273-I275 PolarHBondContact O-N 3.12Å; I275-Y281 HydrophobicContact CB-CD1 3.83Å; I275-Y281 HydrophobicContact CB-CE1 3.94Å; I275-Y281 HydrophobicContact CG1-CD1 4.13Å; I275-Y281 HydrophobicContact CG1-CE1 4.37Å; I275-F282 HydrophobicContact CD1-CD2 4.36Å; I275-F282 HydrophobicContact CG1-CB 4.14Å; I275-F282 HydrophobicContact CG1-CD2 4.09Å; I275-V285 HydrophobicContact CD1-CB 4.21Å; I275-V285 HydrophobicContact CD1-CG1 4.19Å; I275-V285 HydrophobicContact CD1-CG2 4.12Å
276	N	95.7	Very high	97.5	Very high	48 Å²	48	58.2 Å²	58.2	26%	0.257	32%	0.319	S	S	.	.	H	α-helix	trans	-88.3	-33	173.7	-74.1	-76.4	0	0	0	112.3	M237 M272 L273 Q274	M237-N276 WeakPolarHBondContact CE-OD1 3.41Å; M237-N276 PolarHBondContact SD-ND2 3.22Å; M272-N276 PolarHBondContact O-ND2 3.46Å; L273-N276 PolarHBondContact O-N 3.36Å; L273-N276 VanDerWaalsContact O-N 3.08Å; Q274-N276 PolarHBondContact O-N 3.24Å
277	A	96.5	Very high	97.4	Very high	76 Å²	76	54.1 Å²	54.1	63%	0.628	30%	0.301	S	S	*	.	H	α-helix	trans	-83.2	-28.5	-178.2	0	0	0	0	0	113.9	L273 Q274	L273-A277 PolarHBondContact O-N 2.88Å; Q274-A277 PolarHBondContact O-N 3.32Å; Q274-A277 VanDerWaalsContact O-N 3.12Å
278	D	95.9	Very high	97.3	Very high	54 Å²	54	51.6 Å²	51.6	29%	0.289	29%	0.288	S	S	.	.			trans	-118.9	102.5	-175	-179	1.2	0	0	0	111.5	Q274 H280 Y281 F282	Q274-D278 HydrophobicContact CG-CB 4.33Å; Q274-D278 WeakPolarHBondContact O-CB 3.33Å; Q274-D278 PolarHBondContact O-N 2.92Å; D278-H280 PolarHBondContact O-N 3.15Å; D278-H280 WeakPolarHBondContact OD1-CA 3.48Å; D278-H280 WeakPolarHBondContact OD1-CB 3.49Å; D278-H280 IonicContact OD1-CD2 2.75Å; D278-H280 IonicContact OD1-CG 3.15Å; D278-H280 PolarHBondContact OD1-N 2.86Å; D278-Y281 PolarHBondContact O-N 3.34Å; D278-Y281 VanDerWaalsContact O-N 3.16Å; D278-Y281 PolarHBondContact OD1-N 3.17Å; D278-F282 PolarHBondContact O-N 3.02Å
279	P	95	Very high	97.3	Very high	35 Å²	35	51.5 Å²	51.5	23%	0.227	29%	0.288	C	S	.	.	H	α-helix	trans	-64.2	-24.5	177.7	-28	40.4	0	0	0	114.3	F98 T283	F98-P279 HydrophobicContact CE2-CB 3.62Å; F98-P279 HydrophobicContact CE2-CG 4.03Å; F98-P279 HydrophobicContact CZ-CB 3.5Å; F98-P279 VanDerWaalsContact CZ-CB 3.5Å; F98-P279 HydrophobicContact CZ-CG 3.69Å; P279-T283 WeakPolarHBondContact O-CB 3.15Å; P279-T283 PolarHBondContact O-N 3.38Å; P279-T283 PolarHBondContact O-OG1 3.21Å
280	H	96.3	Very high	97.1	Very high	143 Å²	143	51.2 Å²	51.2	66%	0.662	28%	0.279	S	S	*	.	H	α-helix	trans	-70.7	-42.1	173.7	-66.8	-66.1	0	0	0	110.5	D278 T283 Q284	D278-H280 PolarHBondContact O-N 3.15Å; D278-H280 WeakPolarHBondContact OD1-CA 3.48Å; D278-H280 WeakPolarHBondContact OD1-CB 3.49Å; D278-H280 IonicContact OD1-CD2 2.75Å; D278-H280 IonicContact OD1-CG 3.15Å; D278-H280 PolarHBondContact OD1-N 2.86Å; H280-T283 PolarHBondContact O-N 2.88Å; H280-Q284 WeakPolarHBondContact O-CB 3.27Å; H280-Q284 PolarHBondContact O-N 3.45Å
281	Y	97.8	Very high	97	Very high	18 Å²	18	52 Å²	52	7%	0.071	28%	0.276	C	S	.	.	H	α-helix	trans	-61.7	-44.1	173.5	-173.7	-126.2	0	0	0	111.6	R209 K271 Q274 I275 D278 T283 Q284 V285	R209-Y281 PolarHBondContact NH2-OH 3.35Å; K271-Y281 HydrophobicContact CB-CE1 4.47Å; Q274-Y281 HydrophobicContact CB-CD1 4.11Å; Q274-Y281 HydrophobicContact CB-CE1 4.3Å; Q274-Y281 HydrophobicContact CG-CD1 3.74Å; Q274-Y281 HydrophobicContact CG-CE1 4.27Å; Q274-Y281 HydrophobicContact CG-CG 4.24Å; I275-Y281 HydrophobicContact CB-CD1 3.83Å; I275-Y281 HydrophobicContact CB-CE1 3.94Å; I275-Y281 HydrophobicContact CG1-CD1 4.13Å; I275-Y281 HydrophobicContact CG1-CE1 4.37Å; D278-Y281 PolarHBondContact O-N 3.34Å; D278-Y281 VanDerWaalsContact O-N 3.16Å; D278-Y281 PolarHBondContact OD1-N 3.17Å; Y281-T283 VanDerWaalsContact C-N 3.34Å; Y281-T283 PolarHBondContact O-N 3.49Å; Y281-Q284 WeakPolarHBondContact O-CB 3.41Å; Y281-Q284 PolarHBondContact O-N 2.88Å; Y281-V285 HydrophobicContact CD2-CG2 4.35Å; Y281-V285 HydrophobicContact CE1-CG2 4.4Å; Y281-V285 HydrophobicContact CE2-CG2 4.07Å; Y281-V285 WeakPolarHBondContact O-CG2 3.49Å; Y281-V285 PolarHBondContact O-N 3.32Å
282	F	97.3	Very high	96.8	Very high	17 Å²	17	49.9 Å²	49.9	8%	0.075	27%	0.267	C	S	.	.	H	α-helix	trans	-56.4	-47.5	172.4	177.8	-91	0	0	0	112.2	A199 V202 I275 D278 Q284 V285 F286	A199-F282 HydrophobicContact CB-CE2 4.09Å; A199-F282 HydrophobicContact CB-CZ 4.1Å; V202-F282 HydrophobicContact CB-CE2 3.99Å; V202-F282 HydrophobicContact CB-CZ 4.34Å; V202-F282 HydrophobicContact CG1-CD2 4.13Å; V202-F282 HydrophobicContact CG1-CE2 3.84Å; V202-F282 HydrophobicContact CG1-CZ 4.31Å; V202-F282 HydrophobicContact CG2-CE2 4.41Å; V202-F282 HydrophobicContact CG2-CZ 4.27Å; I275-F282 HydrophobicContact CD1-CD2 4.36Å; I275-F282 HydrophobicContact CG1-CB 4.14Å; I275-F282 HydrophobicContact CG1-CD2 4.09Å; D278-F282 PolarHBondContact O-N 3.02Å; F282-Q284 VanDerWaalsContact C-N 3.31Å; F282-Q284 PolarHBondContact O-N 3.18Å; F282-V285 PolarHBondContact O-N 3.49Å; F282-F286 HydrophobicContact CE1-CB 4.45Å; F282-F286 WeakPolarHBondContact O-CB 3.44Å; F282-F286 PolarHBondContact O-N 3.11Å
283	T	96.3	Very high	96.1	Very high	54 Å²	54	50.9 Å²	50.9	33%	0.331	28%	0.276	S	S	.	.	H	α-helix	trans	-62.7	-38.4	-179.9	-57.2	0	0	0	0	111.7	P279 H280 Y281 F286 S287	P279-T283 WeakPolarHBondContact O-CB 3.15Å; P279-T283 PolarHBondContact O-N 3.38Å; P279-T283 PolarHBondContact O-OG1 3.21Å; H280-T283 PolarHBondContact O-N 2.88Å; Y281-T283 VanDerWaalsContact C-N 3.34Å; Y281-T283 PolarHBondContact O-N 3.49Å; T283-F286 PolarHBondContact O-N 3.34Å; T283-S287 WeakPolarHBondContact O-CB 3.34Å; T283-S287 PolarHBondContact O-N 3.05Å
284	Q	97.3	Very high	94.7	Very high	108 Å²	108	47.6 Å²	47.6	51%	0.505	27%	0.268	S	S	.	.	H	α-helix	trans	-61.5	-52.9	174.6	-176.8	-175.1	6.8	0	0	110.9	H280 Y281 F282 F286 S287 D288	H280-Q284 WeakPolarHBondContact O-CB 3.27Å; H280-Q284 PolarHBondContact O-N 3.45Å; Y281-Q284 WeakPolarHBondContact O-CB 3.41Å; Y281-Q284 PolarHBondContact O-N 2.88Å; F282-Q284 VanDerWaalsContact C-N 3.31Å; F282-Q284 PolarHBondContact O-N 3.18Å; Q284-F286 VanDerWaalsContact C-N 3.29Å; Q284-F286 PolarHBondContact O-N 3.19Å; Q284-S287 WeakPolarHBondContact O-CB 3.43Å; Q284-S287 PolarHBondContact O-N 3.15Å; Q284-S287 VanDerWaalsContact O-N 3.12Å; Q284-D288 PolarHBondContact O-N 3.06Å
285	V	98	Very high	93.1	Very high	0 Å²	0	48.8 Å²	48.8	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-60.4	-40.5	179.1	179.1	0	0	0	0	111.4	V202 Y205 M206 I275 Y281 F282 D288 L289	V202-V285 HydrophobicContact CG1-CB 3.93Å; V202-V285 HydrophobicContact CG1-CG1 3.55Å; Y205-V285 HydrophobicContact CD1-CG1 3.7Å; Y205-V285 HydrophobicContact CE1-CG1 4.1Å; M206-V285 HydrophobicContact CB-CG1 3.88Å; M206-V285 HydrophobicContact CG-CG2 4.43Å; I275-V285 HydrophobicContact CD1-CB 4.21Å; I275-V285 HydrophobicContact CD1-CG1 4.19Å; I275-V285 HydrophobicContact CD1-CG2 4.12Å; Y281-V285 HydrophobicContact CD2-CG2 4.35Å; Y281-V285 HydrophobicContact CE1-CG2 4.4Å; Y281-V285 HydrophobicContact CE2-CG2 4.07Å; Y281-V285 WeakPolarHBondContact O-CG2 3.49Å; Y281-V285 PolarHBondContact O-N 3.32Å; F282-V285 PolarHBondContact O-N 3.49Å; V285-D288 PolarHBondContact O-N 3Å; V285-L289 WeakPolarHBondContact O-CB 3.43Å; V285-L289 PolarHBondContact O-N 3.35Å
286	F	96.9	Very high	91.3	Very high	16 Å²	16	51.6 Å²	51.6	7%	0.07	29%	0.286	C	S	.	.	H	α-helix	trans	-61	-45.1	175.5	177.9	-82.5	0	0	0	111.6	V144 A146 L151 V202 F282 T283 Q284 L289 K290	V144-F286 HydrophobicContact CB-CD1 4.22Å; V144-F286 HydrophobicContact CB-CE1 3.66Å; V144-F286 HydrophobicContact CB-CZ 4.33Å; V144-F286 HydrophobicContact CG1-CD1 3.85Å; V144-F286 HydrophobicContact CG1-CE1 3.27Å; V144-F286 HydrophobicContact CG1-CZ 4.24Å; A146-F286 HydrophobicContact CB-CE2 4.29Å; A146-F286 HydrophobicContact CB-CZ 3.74Å; L151-F286 HydrophobicContact CD1-CE2 4.02Å; L151-F286 HydrophobicContact CD2-CE2 4.23Å; V202-F286 HydrophobicContact CG1-CB 4.19Å; V202-F286 HydrophobicContact CG2-CB 4.15Å; V202-F286 HydrophobicContact CG2-CD2 3.54Å; V202-F286 HydrophobicContact CG2-CE2 4.41Å; V202-F286 HydrophobicContact CG2-CG 4.29Å; F282-F286 HydrophobicContact CE1-CB 4.45Å; F282-F286 WeakPolarHBondContact O-CB 3.44Å; F282-F286 PolarHBondContact O-N 3.11Å; T283-F286 PolarHBondContact O-N 3.34Å; Q284-F286 VanDerWaalsContact C-N 3.29Å; Q284-F286 PolarHBondContact O-N 3.19Å; F286-L289 PolarHBondContact O-N 3.48Å; F286-K290 HydrophobicContact CD1-CD 4.1Å; F286-K290 HydrophobicContact CD1-CG 4.41Å; F286-K290 HydrophobicContact CE1-CD 3.28Å; F286-K290 HydrophobicContact CE1-CG 3.93Å; F286-K290 HydrophobicContact CZ-CD 3.75Å; F286-K290 HydrophobicContact CZ-CG 4.28Å; F286-K290 PolarHBondContact O-N 3.41Å
287	S	95.8	Very high	89.5	Confident	52 Å²	52	53.3 Å²	53.3	36%	0.364	30%	0.295	S	S	.	.	H	α-helix	trans	-63.3	-44.9	176.7	179.8	0	0	0	0	111.6	T283 Q284 L289 K290 N291	T283-S287 WeakPolarHBondContact O-CB 3.34Å; T283-S287 PolarHBondContact O-N 3.05Å; Q284-S287 WeakPolarHBondContact O-CB 3.43Å; Q284-S287 PolarHBondContact O-N 3.15Å; Q284-S287 VanDerWaalsContact O-N 3.12Å; S287-L289 VanDerWaalsContact C-N 3.34Å; S287-L289 PolarHBondContact O-N 2.9Å; S287-K290 PolarHBondContact O-N 2.96Å; S287-N291 VanDerWaalsContact O-CG 3.26Å; S287-N291 PolarHBondContact O-N 3.2Å; S287-N291 PolarHBondContact O-ND2 2.75Å
288	D	97.4	Very high	87.8	Confident	51 Å²	51	56.8 Å²	56.8	27%	0.273	30%	0.296	S	S	.	.	H	α-helix	trans	-55.8	-50	176	-65.1	-18.4	0	0	0	110.3	Y205 R209 Q284 V285 K290 N291 E292	Y205-D288 HydrophobicContact CE1-CB 3.97Å; R209-D288 IonicContact NH1-OD2 2.62Å; R209-D288 PolarHBondContact NH1-OD2 3.04Å; Q284-D288 PolarHBondContact O-N 3.06Å; V285-D288 PolarHBondContact O-N 3Å; D288-K290 PolarHBondContact O-N 2.94Å; D288-N291 PolarHBondContact O-N 3.21Å; D288-N291 VanDerWaalsContact O-N 3.11Å; D288-E292 PolarHBondContact O-N 3.48Å
289	L	97.7	Very high	86.1	Confident	0 Å²	0	60.1 Å²	60.1	0%	0	31%	0.308	C	S	.	.	H	α-helix	trans	-59.5	-42.2	178.4	178.8	56.3	0	0	0	112.3	L151 C154 L155 V201 V202 Y205 V285 F286 S287 N291 E292	L151-L289 HydrophobicContact CB-CD2 4.13Å; L151-L289 HydrophobicContact CD2-CD2 3.93Å; L151-L289 HydrophobicContact CD2-CG 4.14Å; C154-L289 HydrophobicContact CB-CD1 3.74Å; C154-L289 HydrophobicContact CB-CG 4.2Å; C154-L289 WeakPolarHBondContact CB-O 3.35Å; L155-L289 HydrophobicContact CB-CD1 4.19Å; V201-L289 HydrophobicContact CG1-CD2 4.06Å; V202-L289 HydrophobicContact CG2-CD2 4.25Å; Y205-L289 HydrophobicContact CD1-CB 3.67Å; Y205-L289 HydrophobicContact CD1-CD1 4.25Å; Y205-L289 HydrophobicContact CD1-CD2 4.47Å; Y205-L289 HydrophobicContact CD1-CG 4.33Å; Y205-L289 HydrophobicContact CD2-CD1 3.79Å; Y205-L289 HydrophobicContact CE1-CB 3.87Å; Y205-L289 HydrophobicContact CE2-CD1 4.3Å; Y205-L289 HydrophobicContact CG-CB 4.08Å; Y205-L289 HydrophobicContact CG-CD1 3.76Å; Y205-L289 HydrophobicContact CG-CD2 4.29Å; Y205-L289 HydrophobicContact CG-CG 4.25Å; V285-L289 WeakPolarHBondContact O-CB 3.43Å; V285-L289 PolarHBondContact O-N 3.35Å; F286-L289 PolarHBondContact O-N 3.48Å; S287-L289 VanDerWaalsContact C-N 3.34Å; S287-L289 PolarHBondContact O-N 2.9Å; L289-N291 VanDerWaalsContact C-N 3.28Å; L289-N291 PolarHBondContact O-N 3.15Å; L289-E292 VanDerWaalsContact O-CB 3.3Å; L289-E292 WeakPolarHBondContact O-CB 3.46Å; L289-E292 PolarHBondContact O-N 3.44Å
290	K	95.7	Very high	84.5	Confident	55 Å²	55	66.5 Å²	66.5	24%	0.239	33%	0.328	C	S	.	.	H	α-helix	trans	-62.3	-39.2	176.5	-76.1	-168.3	67.3	168.3	0	112.1	V144 Q145 A146 L151 F286 S287 D288 E292 S293	V144-K290 HydrophobicContact CG1-CD 4.42Å; Q145-K290 PolarHBondContact O-NZ 3.48Å; A146-K290 HydrophobicContact CB-CD 4.07Å; A146-K290 HydrophobicContact CB-CG 4.43Å; L151-K290 HydrophobicContact CD2-CG 4.03Å; F286-K290 HydrophobicContact CD1-CD 4.1Å; F286-K290 HydrophobicContact CD1-CG 4.41Å; F286-K290 HydrophobicContact CE1-CD 3.28Å; F286-K290 HydrophobicContact CE1-CG 3.93Å; F286-K290 HydrophobicContact CZ-CD 3.75Å; F286-K290 HydrophobicContact CZ-CG 4.28Å; F286-K290 PolarHBondContact O-N 3.41Å; S287-K290 PolarHBondContact O-N 2.96Å; D288-K290 PolarHBondContact O-N 2.94Å; K290-E292 PolarHBondContact O-N 2.88Å; K290-S293 PolarHBondContact O-N 3.37Å; K290-S293 PolarHBondContact O-OG 3.11Å
291	N	95.4	Very high	82.7	Confident	100 Å²	100	65.6 Å²	65.6	54%	0.535	33%	0.327	S	S	.	.	H	α-helix	trans	-70.8	-12.4	-179.2	-67.8	-27.8	0	0	0	113.6	S287 D288 L289 S293 G294	S287-N291 VanDerWaalsContact O-CG 3.26Å; S287-N291 PolarHBondContact O-N 3.2Å; S287-N291 PolarHBondContact O-ND2 2.75Å; D288-N291 PolarHBondContact O-N 3.21Å; D288-N291 VanDerWaalsContact O-N 3.11Å; L289-N291 VanDerWaalsContact C-N 3.28Å; L289-N291 PolarHBondContact O-N 3.15Å; N291-S293 PolarHBondContact O-N 2.93Å; N291-G294 PolarHBondContact O-N 3.2Å
292	E	95.3	Very high	81	Confident	25 Å²	25	69.6 Å²	69.6	12%	0.117	35%	0.349	C	S	.	.	H	α-helix	trans	-61.5	-28.6	173.6	-66.9	-64.3	156.7	0	0	112.8	C154 F158 R161 Y205 D288 L289 K290	C154-E292 HydrophobicContact CB-CB 4.27Å; F158-E292 HydrophobicContact CB-CB 4.13Å; F158-E292 HydrophobicContact CB-CG 3.84Å; F158-E292 HydrophobicContact CD2-CG 4.4Å; F158-E292 HydrophobicContact CG-CG 4.44Å; R161-E292 IonicContact CZ-OE2 3.71Å; R161-E292 IonicContact NH1-OE2 2.72Å; R161-E292 PolarHBondContact NH1-OE2 2.97Å; R161-E292 PolarHBondContact NH2-O 2.87Å; Y205-E292 HydrophobicContact CE2-CG 4.16Å; Y205-E292 PolarHBondContact OH-OE1 3.32Å; Y205-E292 VanDerWaalsContact OH-OE1 3.13Å; D288-E292 PolarHBondContact O-N 3.48Å; L289-E292 VanDerWaalsContact O-CB 3.3Å; L289-E292 WeakPolarHBondContact O-CB 3.46Å; L289-E292 PolarHBondContact O-N 3.44Å; K290-E292 PolarHBondContact O-N 2.88Å
293	S	83.8	Confident	79.5	Confident	30 Å²	30	75.2 Å²	75.2	21%	0.21	38%	0.379	C	S	.	.	H	α-helix	trans	-79.5	-34.5	178	61.2	0	0	0	0	114.2	E157 K290 N291 Q295 E296	E157-S293 WeakPolarHBondContact OE2-CA 3.36Å; E157-S293 VanDerWaalsContact OE2-CB 3.3Å; E157-S293 WeakPolarHBondContact OE2-CB 3.5Å; K290-S293 PolarHBondContact O-N 3.37Å; K290-S293 PolarHBondContact O-OG 3.11Å; N291-S293 PolarHBondContact O-N 2.93Å; S293-Q295 PolarHBondContact O-N 3.13Å; S293-Q295 VanDerWaalsContact O-N 3.14Å; S293-E296 PolarHBondContact O-N 3.12Å
294	G	69	Low	77.7	Confident	39 Å²	39	75.2 Å²	75.2	40%	0.402	39%	0.39	S	S	.	.	H	α-helix	trans	-66.4	-18.8	-176	0	0	0	0	0	114.6	N291 K298	N291-G294 PolarHBondContact O-N 3.2Å; G294-K298 PolarHBondContact O-N 3.13Å; G294-K298 VanDerWaalsContact O-N 3.16Å
295	Q	64.2	Low	76.3	Confident	100 Å²	100	76.7 Å²	76.7	47%	0.467	40%	0.401	S	S	.	.	H	α-helix	trans	-71.2	-32	179.4	-68.8	-163.1	16.5	0	0	113.2	S293 K299	S293-Q295 PolarHBondContact O-N 3.13Å; S293-Q295 VanDerWaalsContact O-N 3.14Å; Q295-K299 WeakPolarHBondContact O-CG 3.2Å; Q295-K299 PolarHBondContact O-N 3.11Å
296	E	59.2	Low	74.4	Confident	62 Å²	62	84 Å²	84	29%	0.29	44%	0.44	S	S	.	.	H	α-helix	trans	-76.2	-40.7	176.9	-69.5	-148.9	152.1	0	0	112	S293 K298 K299 R300	S293-E296 PolarHBondContact O-N 3.12Å; E296-K298 VanDerWaalsContact C-N 3.26Å; E296-K298 PolarHBondContact O-N 3.42Å; E296-K299 PolarHBondContact O-N 3.37Å; E296-K299 VanDerWaalsContact O-N 3.07Å; E296-R300 PolarHBondContact O-N 3.14Å
297	D	58.8	Low	72	Confident	84 Å²	84	97.2 Å²	97.2	45%	0.449	49%	0.489	S	S	.	.	H	α-helix	trans	-61.2	-38.9	176.7	-71.1	-29	0	0	0	110.9	K299 R300 L301	D297-K299 PolarHBondContact O-N 3.33Å; D297-R300 PolarHBondContact O-N 3.25Å; D297-L301 WeakPolarHBondContact O-CB 3.36Å; D297-L301 VanDerWaalsContact O-CG 3.26Å; D297-L301 WeakPolarHBondContact O-CG 3.34Å; D297-L301 PolarHBondContact O-N 3.25Å
298	K	59.8	Low	70.8	Confident	149 Å²	149	99.5 Å²	99.5	65%	0.648	50%	0.495	S	S	*	.	H	α-helix	trans	-64.1	-38.9	173.9	-166.1	171.8	-177.1	176.4	0	112.5	G294 E296 L302	G294-K298 PolarHBondContact O-N 3.13Å; G294-K298 VanDerWaalsContact O-N 3.16Å; E296-K298 VanDerWaalsContact C-N 3.26Å; E296-K298 PolarHBondContact O-N 3.42Å; K298-L302 HydrophobicContact CG-CD1 4.37Å; K298-L302 WeakPolarHBondContact O-CB 3.45Å; K298-L302 VanDerWaalsContact O-CG 3.26Å; K298-L302 WeakPolarHBondContact O-CG 3.35Å; K298-L302 PolarHBondContact O-N 3.31Å
299	K	60.5	Low	69.4	Low	125 Å²	125	102 Å²	102	54%	0.543	51%	0.507	S	S	.	.	H	α-helix	trans	-68	-39.4	175.6	-73.5	-180	-178.3	-176.9	0	112.1	Q295 E296 D297 L302 L303	Q295-K299 WeakPolarHBondContact O-CG 3.2Å; Q295-K299 PolarHBondContact O-N 3.11Å; E296-K299 PolarHBondContact O-N 3.37Å; E296-K299 VanDerWaalsContact O-N 3.07Å; D297-K299 PolarHBondContact O-N 3.33Å; K299-L302 PolarHBondContact O-N 3.04Å; K299-L303 WeakPolarHBondContact O-CG 3.33Å; K299-L303 PolarHBondContact O-N 3.28Å; K299-L303 VanDerWaalsContact O-N 3.08Å
300	R	61.3	Low	67.8	Low	169 Å²	169	107.7 Å²	107.7	64%	0.638	54%	0.535	S	S	*	.	H	α-helix	trans	-66.8	-40.7	176.2	-72.2	-176.6	-176.2	-164.4	3.5	112.2	E296 D297 L303 G304	E296-R300 PolarHBondContact O-N 3.14Å; D297-R300 PolarHBondContact O-N 3.25Å; R300-L303 PolarHBondContact O-N 3.38Å; R300-G304 PolarHBondContact O-N 2.99Å
301	L	59.9	Low	66.2	Low	123 Å²	123	110.8 Å²	110.8	64%	0.644	55%	0.553	S	S	*	*	H	α-helix	trans	-66.3	-38.4	176.3	-71.4	172.8	0	0	0	112.2	D297 G304 L305	D297-L301 WeakPolarHBondContact O-CB 3.36Å; D297-L301 VanDerWaalsContact O-CG 3.26Å; D297-L301 WeakPolarHBondContact O-CG 3.34Å; D297-L301 PolarHBondContact O-N 3.25Å; L301-G304 PolarHBondContact O-N 3.13Å; L301-L305 WeakPolarHBondContact O-CG 3.18Å; L301-L305 PolarHBondContact O-N 3.25Å
302	L	61.3	Low	64.3	Low	103 Å²	103	111.4 Å²	111.4	54%	0.539	55%	0.554	S	S	.	*	H	α-helix	trans	-66.5	-40.8	175.4	-72.3	170.4	0	0	0	112.1	K298 K299 G304 L305	K298-L302 HydrophobicContact CG-CD1 4.37Å; K298-L302 WeakPolarHBondContact O-CB 3.45Å; K298-L302 VanDerWaalsContact O-CG 3.26Å; K298-L302 WeakPolarHBondContact O-CG 3.35Å; K298-L302 PolarHBondContact O-N 3.31Å; K299-L302 PolarHBondContact O-N 3.04Å; L302-G304 VanDerWaalsContact C-N 3.27Å; L302-G304 PolarHBondContact O-N 3Å; L302-L305 PolarHBondContact O-N 3.49Å
303	L	66.2	Low	62.3	Low	134 Å²	134	117.2 Å²	117.2	70%	0.702	58%	0.583	S	S	*	*	H	α-helix	trans	-69	-24.8	175.6	-72.3	166.1	0	0	0	113.4	K299 R300 L305	K299-L303 WeakPolarHBondContact O-CG 3.33Å; K299-L303 PolarHBondContact O-N 3.28Å; K299-L303 VanDerWaalsContact O-N 3.08Å; R300-L303 PolarHBondContact O-N 3.38Å; L303-L305 VanDerWaalsContact C-N 3.35Å
304	G	59.1	Low	60.7	Low	54 Å²	54	123.4 Å²	123.4	56%	0.557	61%	0.61	S	S	*	*	T	Hydrogen-bonded Turn	trans	-80.7	-11.3	176.6	0	0	0	0	0	114.7	R300 L301 L302	R300-G304 PolarHBondContact O-N 2.99Å; L301-G304 PolarHBondContact O-N 3.13Å; L302-G304 VanDerWaalsContact C-N 3.27Å; L302-G304 PolarHBondContact O-N 3Å
305	L	67.3	Low	60.1	Low	140 Å²	140	129.9 Å²	129.9	73%	0.733	63%	0.626	S	S	*	*	S	Bend	trans	-94.8	-10.9	178	-75	164.3	0	0	0	113.4	L301 L302 L303	L301-L305 WeakPolarHBondContact O-CG 3.18Å; L301-L305 PolarHBondContact O-N 3.25Å; L302-L305 PolarHBondContact O-N 3.49Å; L303-L305 VanDerWaalsContact C-N 3.35Å
306	D	57.6	Low	59.7	Low	152 Å²	152	132.4 Å²	132.4	81%	0.813	64%	0.639	S	S	*	*			trans	-100.6	24.9	178.1	-87.9	-35.3	0	0	0	113.4
307	R	46	Very low	59.8	Low	294 Å²	294	138.8 Å²	138.8	100%	1.109	67%	0.67	S	S	*	*			trans	-130.6	0	171.6	-98.6	-172.4	168.3	-167.4	-2.8	111

Retrieved 307 of 307 residues in 50.1 ms (Link to these results)

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