Q5JY90_HUMAN Loading...

Tyrosine-protein kinase

AlphaFold DB , UniProt , Accession Q5JY90, Species HUMAN (Homo sapiens, Human), Gene BTK, Length 483 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M50.4Low83.1Confident242 Ų24254.7 Ų54.7100%1.19232%0.317SS*.  0132.40-83.6-168.9-87.200107.9
2A61.4Low84Confident50 Ų5052 Ų5241%0.41330%0.299SS..PPolyproline II helixtrans-63.5138.817600000110.2
3A81.3Confident84.6Confident80 Ų8048.2 Ų48.266%0.66128%0.277SS*.PPolyproline II helixtrans-62.6138.6177.900000110.8
4V87.7Confident84.7Confident71 Ų7146.8 Ų46.843%0.4327%0.271SS..EExtended strand (participates in β ladder)trans-79126.4172.9179.30000108.2L6 E7 L31 L32 T33V4-L6 WeakPolarHBondContact CG1-O 3.43Å; V4-E7 HydrophobicContact CG1-CB 4.25Å; V4-L31 HydrophobicContact CG1-CB 4.35Å; V4-L31 HydrophobicContact CG1-CD2 4.1Å; V4-L32 CarbonylContact C-O 3.5Å; V4-T33 HydrophobicContact CG2-CG2 4.32Å
5I88.1Confident84.3Confident54 Ų5445.7 Ų45.728%0.27726%0.263SS..EExtended strand (participates in β ladder)trans-86.8-46.9-179.7-55.1174.6000110.4L32 V34 Q127 V131I5-L32 HydrophobicContact CB-CG 4.42Å; I5-L32 HydrophobicContact CD1-CG 4.47Å; I5-L32 PolarHBondContact N-O 2.88Å; I5-V34 HydrophobicContact CD1-CG1 3.76Å; I5-Q127 HydrophobicContact CG2-CG 3.57Å; I5-Q127 VanDerWaalsContact CG2-NE2 3.28Å; I5-V131 HydrophobicContact CD1-CG2 3.83Å
6L88.8Confident83.6Confident12 Ų1244.6 Ų44.66%0.06326%0.255CS..EExtended strand (participates in β ladder)trans-137.4142.8177.3-66.9176.9000110.2V4 L31 L32 W124 Q127V4-L6 WeakPolarHBondContact CG1-O 3.43Å; L6-L31 WeakPolarHBondContact O-CA 3.28Å; L6-L32 HydrophobicContact CB-CB 4.17Å; L6-L32 HydrophobicContact CD1-CD2 4.29Å; L6-L32 PolarHBondContact N-O 3.15Å; L6-L32 PolarHBondContact O-N 3.12Å; L6-W124 HydrophobicContact CB-CD2 4.26Å; L6-W124 HydrophobicContact CB-CH2 3.94Å; L6-W124 HydrophobicContact CB-CZ2 3.56Å; L6-W124 HydrophobicContact CB-CZ3 4.43Å; L6-W124 HydrophobicContact CD1-CB 4.44Å; L6-W124 HydrophobicContact CD1-CD2 3.76Å; L6-W124 HydrophobicContact CD1-CE3 4.25Å; L6-W124 HydrophobicContact CD1-CG 3.84Å; L6-Q127 HydrophobicContact CD1-CB 3.55Å; L6-Q127 HydrophobicContact CD1-CG 3.84Å; L6-Q127 HydrophobicContact CG-CB 4.38Å; L6-Q127 HydrophobicContact CG-CG 4.16Å
7E91.4Very high82.7Confident70 Ų7050.9 Ų50.933%0.32728%0.278SS..EExtended strand (participates in β ladder)trans-135.8125175.9173163.3-148.600108.7V4 L29 F30 L31V4-E7 HydrophobicContact CG1-CB 4.25Å; E7-L29 HydrophobicContact CG-CD1 3.74Å; E7-L29 HydrophobicContact CG-CG 4.47Å; E7-L29 WeakPolarHBondContact OE1-CD2 3.47Å; E7-F30 VanDerWaalsContact CA-O 3.31Å; E7-F30 WeakPolarHBondContact CA-O 3.37Å; E7-L31 HydrophobicContact CB-CD2 3.63Å; E7-L31 HydrophobicContact CG-CD2 3.39Å; E7-L31 WeakPolarHBondContact OE1-CD2 3.29Å
8S88.6Confident81.8Confident5 Ų556.3 Ų56.34%0.03530%0.299CS..EExtended strand (participates in β ladder)trans-158.5151.2179.8-59.70000112F30 W124S8-F30 PolarHBondContact N-O 2.87Å; S8-F30 VanDerWaalsContact N-O 3.07Å; S8-F30 PolarHBondContact O-N 2.93Å; S8-W124 PolarHBondContact OG-NE1 2.79Å
9I90.3Very high80.9Confident13 Ų1362.8 Ų62.87%0.06732%0.324CS..EExtended strand (participates in β ladder)trans-85.7128.4171.2-60.5173.3000108.4R28 L29 Y42 F44 F98 L371I9-R28 WeakPolarHBondContact CA-O 3.3Å; I9-L29 HydrophobicContact CG1-CD1 4.06Å; I9-Y42 HydrophobicContact CD1-CD1 3.56Å; I9-Y42 HydrophobicContact CD1-CD2 4.41Å; I9-Y42 HydrophobicContact CD1-CE1 3.48Å; I9-Y42 VanDerWaalsContact CD1-CE1 3.48Å; I9-Y42 HydrophobicContact CD1-CE2 4.34Å; I9-Y42 HydrophobicContact CD1-CG 4.03Å; I9-Y42 HydrophobicContact CG1-CD1 4.42Å; I9-Y42 HydrophobicContact CG1-CG 4.43Å; I9-F44 HydrophobicContact CD1-CE1 3.8Å; I9-F44 HydrophobicContact CD1-CZ 4.2Å; I9-F44 HydrophobicContact CG2-CZ 4.1Å; I9-F98 HydrophobicContact CG2-CE1 4.45Å; I9-F98 HydrophobicContact CG2-CZ 4.25Å; I9-L371 HydrophobicContact CG1-CD1 4.34Å
10F93.2Very high80.1Confident0 Ų066.1 Ų66.10%035%0.347CS..EExtended strand (participates in β ladder)trans-133.6156.1174.9-65.4-51.8000111.9K27 R28 F30 F102 V113 F114 L120 W124F10-K27 CarbonylContact O-C 3.56Å; F10-K27 WeakPolarHBondContact O-CA 3.44Å; F10-R28 PolarHBondContact N-O 3.19Å; F10-R28 PolarHBondContact O-N 3.16Å; F10-F30 HydrophobicContact CB-CD2 3.78Å; F10-F30 HydrophobicContact CB-CE2 3.8Å; F10-F30 HydrophobicContact CD2-CB 4.02Å; F10-F30 AromaticContact CD2-CD2 3.7Å; F10-F30 HydrophobicContact CD2-CD2 3.7Å; F10-F30 HydrophobicContact CD2-CE2 4.33Å; F10-F30 AromaticContact CD2-CG 3.93Å; F10-F30 HydrophobicContact CD2-CG 3.93Å; F10-F30 HydrophobicContact CE2-CB 4.47Å; F10-F30 HydrophobicContact CG-CD2 4.21Å; F10-F102 HydrophobicContact CD2-CZ 4.39Å; F10-F102 HydrophobicContact CE1-CE1 4.43Å; F10-F102 HydrophobicContact CE2-CE1 4.32Å; F10-F102 HydrophobicContact CE2-CZ 4.07Å; F10-F102 HydrophobicContact CZ-CE1 4.23Å; F10-F102 HydrophobicContact CZ-CZ 4.35Å; F10-V113 HydrophobicContact CB-CG1 3.33Å; F10-V113 HydrophobicContact CD1-CG1 4.33Å; F10-V113 HydrophobicContact CD2-CG1 3.56Å; F10-V113 HydrophobicContact CE2-CG1 4.41Å; F10-V113 HydrophobicContact CG-CG1 3.51Å; F10-F114 WeakPolarHBondContact CB-O 3.42Å; F10-F114 WeakPolarHBondContact CD1-O 3.44Å; F10-L120 HydrophobicContact CE1-CD2 3.75Å; F10-L120 HydrophobicContact CE1-CG 4.05Å; F10-L120 HydrophobicContact CZ-CD2 4.19Å; F10-L120 HydrophobicContact CZ-CG 4.16Å; F10-W124 AromaticContact CE2-CD2 3.53Å; F10-W124 HydrophobicContact CE2-CD2 3.53Å; F10-W124 AromaticContact CE2-CE2 3.41Å; F10-W124 VanDerWaalsContact CE2-CE2 3.41Å; F10-W124 AromaticContact CE2-CE3 3.92Å; F10-W124 HydrophobicContact CE2-CE3 3.92Å; F10-W124 AromaticContact CE2-CG 4Å; F10-W124 HydrophobicContact CE2-CG 4Å; F10-W124 HydrophobicContact CE2-CH2 4.09Å; F10-W124 AromaticContact CE2-CZ2 3.71Å; F10-W124 HydrophobicContact CE2-CZ2 3.71Å; F10-W124 HydrophobicContact CE2-CZ3 4.18Å; F10-W124 AromaticContact CE2-NE1 3.78Å; F10-W124 AromaticContact CZ-CD1 3.56Å; F10-W124 AromaticContact CZ-CD2 3.77Å; F10-W124 HydrophobicContact CZ-CD2 3.77Å; F10-W124 AromaticContact CZ-CE2 3.62Å; F10-W124 AromaticContact CZ-CG 3.73Å; F10-W124 HydrophobicContact CZ-CG 3.73Å; F10-W124 HydrophobicContact CZ-CZ2 4.29Å; F10-W124 AromaticContact CZ-NE1 3.46Å
11L92.9Very high79.5Confident5 Ų564.7 Ų64.73%0.02634%0.343CS..EExtended strand (participates in β ladder)trans-84.6114.7167.8-173.970.6000109.1F25 K27 R77 F98 F114L11-F25 HydrophobicContact CD1-CB 3.82Å; L11-F25 HydrophobicContact CD2-CB 4.07Å; L11-F25 HydrophobicContact CD2-CD1 4.13Å; L11-F25 HydrophobicContact CD2-CG 4.45Å; L11-F25 HydrophobicContact CG-CB 3.93Å; L11-F25 HydrophobicContact CG-CD1 4.26Å; L11-K27 HydrophobicContact CD1-CG 4.14Å; L11-R77 HydrophobicContact CD2-CG 3.91Å; L11-F98 HydrophobicContact CB-CB 3.7Å; L11-F98 HydrophobicContact CB-CD1 4.06Å; L11-F98 HydrophobicContact CB-CD2 3.77Å; L11-F98 HydrophobicContact CB-CE2 4.45Å; L11-F98 HydrophobicContact CB-CG 3.56Å; L11-F98 HydrophobicContact CD2-CB 4.17Å; L11-F98 HydrophobicContact CD2-CD2 4.39Å; L11-F114 HydrophobicContact CB-CB 4.15Å; L11-F114 PolarHBondContact N-O 3.47Å; L11-F114 PolarHBondContact O-N 2.76Å
12K94.3Very high80.4Confident22 Ų2257.2 Ų57.210%0.09631%0.313CS..EExtended strand (participates in β ladder)trans-95.7128.6-179.6-176.6-166.8174.1-56.60110.4F25 K26 R28 F30 Y39 L111K12-F25 WeakPolarHBondContact O-CA 3.48Å; K12-K26 PolarHBondContact N-O 3.33Å; K12-K26 PolarHBondContact O-N 3.24Å; K12-R28 HydrophobicContact CB-CG 4.07Å; K12-R28 HydrophobicContact CD-CG 4.3Å; K12-F30 HydrophobicContact CB-CE2 4.13Å; K12-F30 HydrophobicContact CB-CZ 3.98Å; K12-F30 HydrophobicContact CD-CZ 4.23Å; K12-F30 HydrophobicContact CG-CZ 4.04Å; K12-Y39 HydrophobicContact CD-CD2 4.11Å; K12-Y39 HydrophobicContact CD-CE2 4Å; K12-L111 HydrophobicContact CD-CD1 4.21Å; K12-L111 VanDerWaalsContact CE-CD1 3.45Å; K12-L111 HydrophobicContact CG-CD1 3.93Å
13R91.3Very high81.3Confident2 Ų257.7 Ų57.71%0.00831%0.308CS..EExtended strand (participates in β ladder)trans-80.1144.6169.5-166.1171.7172.2-141.8-23.8111.2L23 N24 F25 Y112 F114 W147R13-L23 HydrophobicContact CG-CD1 4.02Å; R13-L23 HydrophobicContact CG-CG 4.34Å; R13-L23 VanDerWaalsContact NE-CD1 3.26Å; R13-L23 VanDerWaalsContact NH2-CD1 3.27Å; R13-N24 CarbonylContact C-O 3.6Å; R13-F25 HydrophobicContact CB-CD1 4.1Å; R13-F25 HydrophobicContact CB-CE1 3.88Å; R13-F25 HydrophobicContact CG-CD1 4.22Å; R13-F25 HydrophobicContact CG-CE1 3.67Å; R13-F25 HydrophobicContact CG-CZ 3.84Å; R13-Y112 PolarHBondContact N-O 3.46Å; R13-Y112 VanDerWaalsContact N-O 3.08Å; R13-F114 HydrophobicContact CB-CE2 4.23Å; R13-W147 PolarHBondContact NH1-O 2.81Å; R13-W147 PolarHBondContact NH2-O 2.78Å
14S85.8Confident81.5Confident29 Ų2957.7 Ų57.720%0.20330%0.297CS..PPolyproline II helixtrans-64.9139.1171.372.90000109.7Q16 P22 N24S14-Q16 PolarHBondContact O-N 2.88Å; S14-P22 PolarHBondContact OG-O 2.84Å; S14-N24 PolarHBondContact N-O 2.84Å; S14-N24 PolarHBondContact OG-N 3.17Å; S14-N24 VanDerWaalsContact OG-N 3.15Å
15Q78.6Confident81.6Confident30 Ų3056.4 Ų56.414%0.1429%0.286CS..  trans-81.7-0.5-178.4-70.9166.1-7300113.1Y106 L111 K160Q15-Y106 VanDerWaalsContact NE2-CE1 3.32Å; Q15-Y106 PolarHBondContact NE2-OH 3.06Å; Q15-L111 HydrophobicContact CG-CD1 3.95Å; Q15-K160 PolarHBondContact O-NZ 2.76Å
16Q73.1Confident81.7Confident29 Ų2959.3 Ų59.314%0.13630%0.296CS..  trans43.369.9-177.6-62.8-179.2-63.100112S14 K18 S21 L23 K160S14-Q16 PolarHBondContact O-N 2.88Å; Q16-K18 PolarHBondContact O-N 3.3Å; Q16-S21 PolarHBondContact NE2-O 2.99Å; Q16-L23 HydrophobicContact CG-CD1 3.8Å; Q16-K160 PolarHBondContact O-NZ 3.29Å
17K68.9Low81.8Confident151 Ų15161.9 Ų61.966%0.65731%0.307SS*.SBendtrans-59.6-25.3179-65.8-161.2174.9-151.40112.1E108K17-E108 VanDerWaalsContact NZ-CD 3.31Å; K17-E108 IonicContact NZ-OE1 3.94Å; K17-E108 PolarHBondContact NZ-OE1 3.06Å; K17-E108 IonicContact NZ-OE2 2.64Å; K17-E108 PolarHBondContact NZ-OE2 3.17Å
18K67.3Low81.8Confident148 Ų14860 Ų6064%0.64330%0.297SS*.SBendtrans-118.2147.4168.3-57.4-179.6179.8-178.30109.9Q16 T20 S21Q16-K18 PolarHBondContact O-N 3.3Å; K18-T20 PolarHBondContact O-N 2.92Å; K18-S21 VanDerWaalsContact O-CB 3.29Å; K18-S21 WeakPolarHBondContact O-CB 3.3Å; K18-S21 PolarHBondContact O-N 2.75Å; K18-S21 PolarHBondContact O-OG 2.87Å
19K63.2Low82Confident180 Ų18060 Ų6078%0.78330%0.296SS*.THydrogen-bonded Turntrans-58.3-29.9-179.6-165175.2-178.6179.60113.2
20T64.6Low82.2Confident129 Ų12959.5 Ų59.579%0.79129%0.294SS*.THydrogen-bonded Turntrans-86.8-2.8178.654.40000114.2K18K18-T20 PolarHBondContact O-N 2.92Å
21S69.5Low82.2Confident36 Ų3660 Ų6025%0.25230%0.296SS..SBendtrans-71.2133.8-177.9-65.40000111.2Q16 K18Q16-S21 PolarHBondContact NE2-O 2.99Å; K18-S21 VanDerWaalsContact O-CB 3.29Å; K18-S21 WeakPolarHBondContact O-CB 3.3Å; K18-S21 PolarHBondContact O-N 2.75Å; K18-S21 PolarHBondContact O-OG 2.87Å
22P68.4Low82.2Confident86 Ų8659.7 Ų59.756%0.55830%0.295SS*.  trans-61.8144.418023.7-32.6000111.5S14 N24S14-P22 PolarHBondContact OG-O 2.84Å; P22-N24 PolarHBondContact O-N 2.92Å
23L80.5Confident82.1Confident60 Ų6059.7 Ų59.731%0.31430%0.296SS..  trans-82.599.2175.6-161.873.6000109.4R13 Q16 F25R13-L23 HydrophobicContact CG-CD1 4.02Å; R13-L23 HydrophobicContact CG-CG 4.34Å; R13-L23 VanDerWaalsContact NE-CD1 3.26Å; R13-L23 VanDerWaalsContact NH2-CD1 3.27Å; Q16-L23 HydrophobicContact CG-CD1 3.8Å; L23-F25 HydrophobicContact CD2-CE2 4.14Å; L23-F25 HydrophobicContact CD2-CZ 4.25Å; L23-F25 HydrophobicContact CG-CE2 4.17Å; L23-F25 HydrophobicContact CG-CZ 4.49Å
24N86.1Confident82Confident80 Ų8063.3 Ų63.343%0.42832%0.318SS..  trans-112.1145.1-175.3-71.1-35.5000110.3R13 S14 P22R13-N24 CarbonylContact C-O 3.6Å; S14-N24 PolarHBondContact N-O 2.84Å; S14-N24 PolarHBondContact OG-N 3.17Å; S14-N24 VanDerWaalsContact OG-N 3.15Å; P22-N24 PolarHBondContact O-N 2.92Å
25F89.2Confident82.3Confident44 Ų4468 Ų6819%0.19334%0.337CS..EExtended strand (participates in β ladder)trans-115.2132.2174.9-63.7-99.2000108.4L11 K12 R13 L23 F114L11-F25 HydrophobicContact CD1-CB 3.82Å; L11-F25 HydrophobicContact CD2-CB 4.07Å; L11-F25 HydrophobicContact CD2-CD1 4.13Å; L11-F25 HydrophobicContact CD2-CG 4.45Å; L11-F25 HydrophobicContact CG-CB 3.93Å; L11-F25 HydrophobicContact CG-CD1 4.26Å; K12-F25 WeakPolarHBondContact O-CA 3.48Å; R13-F25 HydrophobicContact CB-CD1 4.1Å; R13-F25 HydrophobicContact CB-CE1 3.88Å; R13-F25 HydrophobicContact CG-CD1 4.22Å; R13-F25 HydrophobicContact CG-CE1 3.67Å; R13-F25 HydrophobicContact CG-CZ 3.84Å; L23-F25 HydrophobicContact CD2-CE2 4.14Å; L23-F25 HydrophobicContact CD2-CZ 4.25Å; L23-F25 HydrophobicContact CG-CE2 4.17Å; L23-F25 HydrophobicContact CG-CZ 4.49Å; F25-F114 HydrophobicContact CD1-CE2 4.21Å; F25-F114 HydrophobicContact CE1-CD2 4.42Å; F25-F114 AromaticContact CE1-CE2 3.67Å; F25-F114 HydrophobicContact CE1-CE2 3.67Å; F25-F114 AromaticContact CE1-CZ 3.86Å; F25-F114 HydrophobicContact CE1-CZ 3.86Å
26K89.7Confident83.1Confident114 Ų11470.6 Ų70.650%0.49635%0.348SS..EExtended strand (participates in β ladder)trans-138.7132.2179.2-62.8-164.9175.5-168.20110.9K12 R28K12-K26 PolarHBondContact N-O 3.33Å; K12-K26 PolarHBondContact O-N 3.24Å; K26-R28 PolarHBondContact O-N 2.83Å
27K90.7Very high84.2Confident67 Ų6769.4 Ų69.429%0.29134%0.342SS..EExtended strand (participates in β ladder)trans-63.3131.7171.8-59.1-174-170.3-1760109.2F10 L11 F44 I95 F98F10-K27 CarbonylContact O-C 3.56Å; F10-K27 WeakPolarHBondContact O-CA 3.44Å; L11-K27 HydrophobicContact CD1-CG 4.14Å; K27-F44 HydrophobicContact CB-CE2 4.29Å; K27-F44 HydrophobicContact CB-CZ 4.22Å; K27-F44 HydrophobicContact CD-CE2 4.06Å; K27-F44 HydrophobicContact CD-CZ 3.72Å; K27-I95 WeakPolarHBondContact CE-O 3.48Å; K27-I95 PolarHBondContact NZ-O 3Å; K27-F98 HydrophobicContact CD-CE2 4.15Å; K27-F98 HydrophobicContact CD-CZ 4.41Å; K27-F98 HydrophobicContact CG-CE2 4.25Å
28R92.5Very high85.4Confident31 Ų3162.6 Ų62.612%0.11731%0.314CS..EExtended strand (participates in β ladder)trans-141.8141.4-178.7-65.4-65.6177.1-111.418.3109.6I9 F10 K12 K26 F30 Y40I9-R28 WeakPolarHBondContact CA-O 3.3Å; F10-R28 PolarHBondContact N-O 3.19Å; F10-R28 PolarHBondContact O-N 3.16Å; K12-R28 HydrophobicContact CB-CG 4.07Å; K12-R28 HydrophobicContact CD-CG 4.3Å; K26-R28 PolarHBondContact O-N 2.83Å; R28-F30 HydrophobicContact CB-CD2 4.09Å; R28-F30 HydrophobicContact CB-CE2 3.72Å; R28-F30 WeakPolarHBondContact O-CD2 3.32Å; R28-Y40 WeakPolarHBondContact CA-O 3.34Å; R28-Y40 WeakPolarHBondContact CD-O 3.42Å
29L91.6Very high86.7Confident5 Ų556.8 Ų56.83%0.02629%0.288CS..EExtended strand (participates in β ladder)trans-80.4115.8168.1-179.569.9000108.3E7 I9 L31 Y39 Y40 Y42 R49E7-L29 HydrophobicContact CG-CD1 3.74Å; E7-L29 HydrophobicContact CG-CG 4.47Å; E7-L29 WeakPolarHBondContact OE1-CD2 3.47Å; I9-L29 HydrophobicContact CG1-CD1 4.06Å; L29-L31 HydrophobicContact CD2-CD2 4.49Å; L29-L31 HydrophobicContact CG-CD2 4.38Å; L29-Y39 CarbonylContact O-C 3.55Å; L29-Y39 VanDerWaalsContact O-CA 3.23Å; L29-Y39 WeakPolarHBondContact O-CA 3.38Å; L29-Y40 PolarHBondContact N-O 2.81Å; L29-Y40 PolarHBondContact O-N 2.8Å; L29-Y42 HydrophobicContact CB-CD2 4.06Å; L29-Y42 HydrophobicContact CB-CG 4.5Å; L29-Y42 HydrophobicContact CD1-CD2 4.29Å; L29-Y42 HydrophobicContact CD2-CD2 4.04Å; L29-Y42 HydrophobicContact CD2-CE2 4.5Å; L29-Y42 HydrophobicContact CG-CD2 4.37Å; L29-R49 HydrophobicContact CD2-CB 3.92Å; L29-R49 HydrophobicContact CD2-CG 3.94Å
30F94.8Very high88.1Confident2 Ų249.7 Ų49.71%0.00926%0.256CS..EExtended strand (participates in β ladder)trans-96.4134.3176-77.8-102.1000110.4E7 S8 F10 K12 R28 L37 S38 Y39 L111 V113 W124E7-F30 VanDerWaalsContact CA-O 3.31Å; E7-F30 WeakPolarHBondContact CA-O 3.37Å; S8-F30 PolarHBondContact N-O 2.87Å; S8-F30 VanDerWaalsContact N-O 3.07Å; S8-F30 PolarHBondContact O-N 2.93Å; F10-F30 HydrophobicContact CB-CD2 3.78Å; F10-F30 HydrophobicContact CB-CE2 3.8Å; F10-F30 HydrophobicContact CD2-CB 4.02Å; F10-F30 AromaticContact CD2-CD2 3.7Å; F10-F30 HydrophobicContact CD2-CD2 3.7Å; F10-F30 HydrophobicContact CD2-CE2 4.33Å; F10-F30 AromaticContact CD2-CG 3.93Å; F10-F30 HydrophobicContact CD2-CG 3.93Å; F10-F30 HydrophobicContact CE2-CB 4.47Å; F10-F30 HydrophobicContact CG-CD2 4.21Å; K12-F30 HydrophobicContact CB-CE2 4.13Å; K12-F30 HydrophobicContact CB-CZ 3.98Å; K12-F30 HydrophobicContact CD-CZ 4.23Å; K12-F30 HydrophobicContact CG-CZ 4.04Å; R28-F30 HydrophobicContact CB-CD2 4.09Å; R28-F30 HydrophobicContact CB-CE2 3.72Å; R28-F30 WeakPolarHBondContact O-CD2 3.32Å; F30-L37 HydrophobicContact CD1-CD1 4.11Å; F30-L37 HydrophobicContact CD1-CG 4.48Å; F30-S38 CarbonylContact C-O 3.54Å; F30-S38 WeakPolarHBondContact CA-O 3.45Å; F30-Y39 HydrophobicContact CD1-CD1 4.3Å; F30-Y39 HydrophobicContact CD1-CG 4.45Å; F30-Y39 AromaticContact CE1-CD1 3.78Å; F30-Y39 HydrophobicContact CE1-CD1 3.78Å; F30-Y39 HydrophobicContact CE1-CG 4.03Å; F30-Y39 HydrophobicContact CZ-CD1 4.35Å; F30-Y39 HydrophobicContact CZ-CG 4.27Å; F30-L111 HydrophobicContact CE1-CD2 4.13Å; F30-V113 HydrophobicContact CE1-CG2 4.1Å; F30-V113 HydrophobicContact CE2-CG1 4.16Å; F30-V113 HydrophobicContact CZ-CG1 4.16Å; F30-V113 HydrophobicContact CZ-CG2 3.92Å; F30-W124 HydrophobicContact CB-CH2 3.68Å; F30-W124 HydrophobicContact CB-CZ2 4.4Å; F30-W124 HydrophobicContact CB-CZ3 4.2Å
31L93.4Very high89.3Confident9 Ų947 Ų475%0.04724%0.235CC..EExtended strand (participates in β ladder)trans-122.5118.7174.6-58.1-177.1000109.1V4 L6 E7 L29 S38 Y40V4-L31 HydrophobicContact CG1-CB 4.35Å; V4-L31 HydrophobicContact CG1-CD2 4.1Å; L6-L31 WeakPolarHBondContact O-CA 3.28Å; E7-L31 HydrophobicContact CB-CD2 3.63Å; E7-L31 HydrophobicContact CG-CD2 3.39Å; E7-L31 WeakPolarHBondContact OE1-CD2 3.29Å; L29-L31 HydrophobicContact CD2-CD2 4.49Å; L29-L31 HydrophobicContact CG-CD2 4.38Å; L31-S38 PolarHBondContact N-O 3.06Å; L31-S38 PolarHBondContact O-N 2.81Å; L31-Y40 HydrophobicContact CB-CE2 4.26Å; L31-Y40 HydrophobicContact CD1-CD2 4.02Å; L31-Y40 HydrophobicContact CD1-CE2 3.48Å; L31-Y40 VanDerWaalsContact CD1-CE2 3.48Å; L31-Y40 HydrophobicContact CG-CD2 4.15Å; L31-Y40 HydrophobicContact CG-CE2 3.86Å
32L93.3Very high89.8Confident0 Ų047.5 Ų47.50%023%0.232CC..EExtended strand (participates in β ladder)trans-96.5128.1171.7179.960.6000109.5V4 I5 L6 L37 V58 W124 Q127 L128V4-L32 CarbonylContact C-O 3.5Å; I5-L32 HydrophobicContact CB-CG 4.42Å; I5-L32 HydrophobicContact CD1-CG 4.47Å; I5-L32 PolarHBondContact N-O 2.88Å; L6-L32 HydrophobicContact CB-CB 4.17Å; L6-L32 HydrophobicContact CD1-CD2 4.29Å; L6-L32 PolarHBondContact N-O 3.15Å; L6-L32 PolarHBondContact O-N 3.12Å; L32-L37 HydrophobicContact CB-CD1 4.3Å; L32-L37 HydrophobicContact CD1-CB 4.28Å; L32-L37 HydrophobicContact CD1-CD1 4.28Å; L32-V58 HydrophobicContact CD1-CG2 4.14Å; L32-W124 HydrophobicContact CB-CH2 4.23Å; L32-W124 HydrophobicContact CB-CZ3 4.02Å; L32-Q127 HydrophobicContact CD2-CG 4.12Å; L32-L128 HydrophobicContact CD1-CD2 3.6Å; L32-L128 HydrophobicContact CD2-CD2 3.79Å; L32-L128 HydrophobicContact CD2-CG 4.02Å; L32-L128 HydrophobicContact CG-CD2 4.33Å
33T92.6Very high90.2Very high22 Ų2246.4 Ų46.414%0.13522%0.221CC..EExtended strand (participates in β ladder)trans-120.2173.1166.664.20000108.6V4 H35 K36V4-T33 HydrophobicContact CG2-CG2 4.32Å; T33-H35 PolarHBondContact O-N 2.88Å; T33-H35 VanDerWaalsContact O-N 3.17Å; T33-H35 PolarHBondContact OG1-N 2.73Å; T33-K36 PolarHBondContact N-O 2.69Å; T33-K36 PolarHBondContact OG1-N 2.94Å; T33-K36 PolarHBondContact OG1-O 2.95Å
34V88.9Confident89.6Confident77 Ų7747.9 Ų47.947%0.46723%0.225SC..SBendtrans-60.3-23.2174.9-69.80000113.4I5I5-V34 HydrophobicContact CD1-CG1 3.76Å
35H91.8Very high88.6Confident127 Ų12752.7 Ų52.759%0.58825%0.245SC*.SBendtrans-110.2-29.4-175.5-58.5-56.3000114T33 V58T33-H35 PolarHBondContact O-N 2.88Å; T33-H35 VanDerWaalsContact O-N 3.17Å; T33-H35 PolarHBondContact OG1-N 2.73Å; H35-V58 WeakPolarHBondContact O-CB 3.3Å; H35-V58 PolarHBondContact O-N 3.33Å
36K94.5Very high87.2Confident86 Ų8659.6 Ų59.637%0.37427%0.27SS..EExtended strand (participates in β ladder)trans-142.6140.5-173.2-59.3-170.8-173.7-102.80112.3T33 I56 D57T33-K36 PolarHBondContact N-O 2.69Å; T33-K36 PolarHBondContact OG1-N 2.94Å; T33-K36 PolarHBondContact OG1-O 2.95Å; K36-I56 CarbonylContact C-O 3.57Å; K36-I56 WeakPolarHBondContact CA-O 3.47Å; K36-D57 WeakPolarHBondContact CE-OD1 3.5Å; K36-D57 WeakPolarHBondContact CG-OD1 3.38Å; K36-D57 IonicContact NZ-OD1 2.79Å; K36-D57 PolarHBondContact NZ-OD1 2.74Å
37L95.9Very high86.2Confident3 Ų356 Ų562%0.01627%0.266CS..EExtended strand (participates in β ladder)trans-98.1104.1161.7176.162.6000108.3F30 L32 S55 I56 V104 W124F30-L37 HydrophobicContact CD1-CD1 4.11Å; F30-L37 HydrophobicContact CD1-CG 4.48Å; L32-L37 HydrophobicContact CB-CD1 4.3Å; L32-L37 HydrophobicContact CD1-CB 4.28Å; L32-L37 HydrophobicContact CD1-CD1 4.28Å; L37-S55 CarbonylContact O-C 3.55Å; L37-S55 VanDerWaalsContact O-CA 3.23Å; L37-S55 WeakPolarHBondContact O-CA 3.28Å; L37-I56 HydrophobicContact CB-CB 4.46Å; L37-I56 PolarHBondContact N-O 2.68Å; L37-I56 PolarHBondContact O-N 3.06Å; L37-V104 HydrophobicContact CD2-CG1 4.17Å; L37-V104 HydrophobicContact CD2-CG2 4.15Å; L37-W124 HydrophobicContact CD1-CZ3 3.81Å
38S95.4Very high85.4Confident9 Ų961.6 Ų61.66%0.06329%0.285CS..EExtended strand (participates in β ladder)trans-107.6149.7-177.8-61.50000111.4F30 L31 S55F30-S38 CarbonylContact C-O 3.54Å; F30-S38 WeakPolarHBondContact CA-O 3.45Å; L31-S38 PolarHBondContact N-O 3.06Å; L31-S38 PolarHBondContact O-N 2.81Å; S38-S55 WeakPolarHBondContact OG-CB 3.45Å
39Y94.8Very high84.9Confident25 Ų2567 Ų6710%0.09831%0.305CS..EExtended strand (participates in β ladder)trans-135.6141.7174.853.8-95.1000112.8K12 L29 F30 K53 G54 L111K12-Y39 HydrophobicContact CD-CD2 4.11Å; K12-Y39 HydrophobicContact CD-CE2 4Å; L29-Y39 CarbonylContact O-C 3.55Å; L29-Y39 VanDerWaalsContact O-CA 3.23Å; L29-Y39 WeakPolarHBondContact O-CA 3.38Å; F30-Y39 HydrophobicContact CD1-CD1 4.3Å; F30-Y39 HydrophobicContact CD1-CG 4.45Å; F30-Y39 AromaticContact CE1-CD1 3.78Å; F30-Y39 HydrophobicContact CE1-CD1 3.78Å; F30-Y39 HydrophobicContact CE1-CG 4.03Å; F30-Y39 HydrophobicContact CZ-CD1 4.35Å; F30-Y39 HydrophobicContact CZ-CG 4.27Å; Y39-K53 HydrophobicContact CD2-CB 3.83Å; Y39-K53 VanDerWaalsContact CE2-C 3.48Å; Y39-K53 HydrophobicContact CE2-CB 3.86Å; Y39-K53 PolarHBondContact O-N 2.99Å; Y39-G54 VanDerWaalsContact CZ-CA 3.49Å; Y39-G54 PolarHBondContact N-O 3.35Å; Y39-G54 PolarHBondContact O-N 3.45Å; Y39-L111 HydrophobicContact CE1-CD2 4.46Å
40Y92.5Very high84.4Confident31 Ų3168.3 Ų68.312%0.12232%0.32CS..EExtended strand (participates in β ladder)trans-127.7159.4-168.5-57.2-102.3000110.8R28 L29 L31 R49 S51 K52R28-Y40 WeakPolarHBondContact CA-O 3.34Å; R28-Y40 WeakPolarHBondContact CD-O 3.42Å; L29-Y40 PolarHBondContact N-O 2.81Å; L29-Y40 PolarHBondContact O-N 2.8Å; L31-Y40 HydrophobicContact CB-CE2 4.26Å; L31-Y40 HydrophobicContact CD1-CD2 4.02Å; L31-Y40 HydrophobicContact CD1-CE2 3.48Å; L31-Y40 VanDerWaalsContact CD1-CE2 3.48Å; L31-Y40 HydrophobicContact CG-CD2 4.15Å; L31-Y40 HydrophobicContact CG-CE2 3.86Å; Y40-R49 HydrophobicContact CD1-CG 3.66Å; Y40-R49 HydrophobicContact CD2-CG 4.27Å; Y40-R49 HydrophobicContact CE1-CG 4.37Å; Y40-R49 HydrophobicContact CG-CG 3.62Å; Y40-S51 WeakPolarHBondContact CA-O 3.37Å; Y40-K52 VanDerWaalsContact CD1-CA 3.45Å; Y40-K52 HydrophobicContact CD1-CB 3.72Å; Y40-K52 HydrophobicContact CD1-CG 4.13Å; Y40-K52 HydrophobicContact CE1-CB 3.59Å; Y40-K52 HydrophobicContact CE1-CD 4.27Å; Y40-K52 HydrophobicContact CE1-CG 3.77Å
41E88.6Confident84.1Confident73 Ų7370.9 Ų70.934%0.34134%0.338SS..EExtended strand (participates in β ladder)trans-62.5146.9156.6-92.3166.4-176.900110.1G50 S51 K53E41-G50 WeakPolarHBondContact O-CA 3.38Å; E41-G50 PolarHBondContact O-N 2.89Å; E41-S51 PolarHBondContact N-O 3.07Å; E41-S51 PolarHBondContact OE2-OG 2.84Å; E41-K53 HydrophobicContact CG-CG 4.26Å; E41-K53 WeakPolarHBondContact OE1-CE 3.24Å; E41-K53 IonicContact OE1-NZ 2.69Å; E41-K53 PolarHBondContact OE1-NZ 3.4Å; E41-K53 WeakPolarHBondContact OE2-CE 3.45Å; E41-K53 IonicContact OE2-NZ 3.61Å; E41-K53 PolarHBondContact OE2-NZ 3.06Å
42Y81.4Confident84Confident47 Ų4775.5 Ų75.518%0.18436%0.358CS..EExtended strand (participates in β ladder)trans-120.2124.2175.3-170.2-107000108.1I9 L29 F44I9-Y42 HydrophobicContact CD1-CD1 3.56Å; I9-Y42 HydrophobicContact CD1-CD2 4.41Å; I9-Y42 HydrophobicContact CD1-CE1 3.48Å; I9-Y42 VanDerWaalsContact CD1-CE1 3.48Å; I9-Y42 HydrophobicContact CD1-CE2 4.34Å; I9-Y42 HydrophobicContact CD1-CG 4.03Å; I9-Y42 HydrophobicContact CG1-CD1 4.42Å; I9-Y42 HydrophobicContact CG1-CG 4.43Å; L29-Y42 HydrophobicContact CB-CD2 4.06Å; L29-Y42 HydrophobicContact CB-CG 4.5Å; L29-Y42 HydrophobicContact CD1-CD2 4.29Å; L29-Y42 HydrophobicContact CD2-CD2 4.04Å; L29-Y42 HydrophobicContact CD2-CE2 4.5Å; L29-Y42 HydrophobicContact CG-CD2 4.37Å; Y42-F44 HydrophobicContact CD1-CB 4.47Å; Y42-F44 AromaticContact CD1-CD1 3.58Å; Y42-F44 HydrophobicContact CD1-CD1 3.58Å; Y42-F44 AromaticContact CD1-CD2 3.79Å; Y42-F44 HydrophobicContact CD1-CD2 3.79Å; Y42-F44 AromaticContact CD1-CE1 3.59Å; Y42-F44 HydrophobicContact CD1-CE1 3.59Å; Y42-F44 AromaticContact CD1-CE2 3.8Å; Y42-F44 HydrophobicContact CD1-CE2 3.8Å; Y42-F44 AromaticContact CD1-CG 3.67Å; Y42-F44 HydrophobicContact CD1-CG 3.67Å; Y42-F44 AromaticContact CD1-CZ 3.7Å; Y42-F44 HydrophobicContact CD1-CZ 3.7Å; Y42-F44 AromaticContact CE1-CD1 3.61Å; Y42-F44 HydrophobicContact CE1-CD1 3.61Å; Y42-F44 AromaticContact CE1-CE1 3.87Å; Y42-F44 HydrophobicContact CE1-CE1 3.87Å; Y42-F44 AromaticContact CE1-CG 3.98Å; Y42-F44 HydrophobicContact CE1-CG 3.98Å; Y42-F44 HydrophobicContact CE1-CZ 4.44Å
43D76.6Confident84Confident63 Ų6379.7 Ų79.734%0.33738%0.376SS..EExtended strand (participates in β ladder)trans-90.4102.6173.1-173.9-17.4000107.7E45 R46 G47 R48D43-E45 VanDerWaalsContact C-N 3.29Å; D43-E45 WeakPolarHBondContact OD1-CB 3.47Å; D43-E45 PolarHBondContact OD1-N 3.45Å; D43-E45 VanDerWaalsContact OD1-N 3.1Å; D43-R46 HydrophobicContact CB-CB 4.41Å; D43-R46 PolarHBondContact O-N 2.95Å; D43-R46 PolarHBondContact OD1-N 2.94Å; D43-R46 WeakPolarHBondContact OD2-CD 3.3Å; D43-R46 WeakPolarHBondContact OD2-CG 3.49Å; D43-G47 PolarHBondContact O-N 2.83Å; D43-R48 PolarHBondContact N-O 3.01Å; D43-R48 VanDerWaalsContact N-O 3.08Å; D43-R48 PolarHBondContact O-N 3Å
44F68.1Low84Confident91 Ų9179.5 Ų79.540%0.39938%0.379SS..THydrogen-bonded Turntrans-69.6-26.8-178.5-70.9-89.8000112.3I9 K27 Y42I9-F44 HydrophobicContact CD1-CE1 3.8Å; I9-F44 HydrophobicContact CD1-CZ 4.2Å; I9-F44 HydrophobicContact CG2-CZ 4.1Å; K27-F44 HydrophobicContact CB-CE2 4.29Å; K27-F44 HydrophobicContact CB-CZ 4.22Å; K27-F44 HydrophobicContact CD-CE2 4.06Å; K27-F44 HydrophobicContact CD-CZ 3.72Å; Y42-F44 HydrophobicContact CD1-CB 4.47Å; Y42-F44 AromaticContact CD1-CD1 3.58Å; Y42-F44 HydrophobicContact CD1-CD1 3.58Å; Y42-F44 AromaticContact CD1-CD2 3.79Å; Y42-F44 HydrophobicContact CD1-CD2 3.79Å; Y42-F44 AromaticContact CD1-CE1 3.59Å; Y42-F44 HydrophobicContact CD1-CE1 3.59Å; Y42-F44 AromaticContact CD1-CE2 3.8Å; Y42-F44 HydrophobicContact CD1-CE2 3.8Å; Y42-F44 AromaticContact CD1-CG 3.67Å; Y42-F44 HydrophobicContact CD1-CG 3.67Å; Y42-F44 AromaticContact CD1-CZ 3.7Å; Y42-F44 HydrophobicContact CD1-CZ 3.7Å; Y42-F44 AromaticContact CE1-CD1 3.61Å; Y42-F44 HydrophobicContact CE1-CD1 3.61Å; Y42-F44 AromaticContact CE1-CE1 3.87Å; Y42-F44 HydrophobicContact CE1-CE1 3.87Å; Y42-F44 AromaticContact CE1-CG 3.98Å; Y42-F44 HydrophobicContact CE1-CG 3.98Å; Y42-F44 HydrophobicContact CE1-CZ 4.44Å
45E63.7Low84.2Confident181 Ų18178 Ų7885%0.84637%0.372SS*.THydrogen-bonded Turntrans-74.5-32.2179.1-64-64.9145.400111.7D43D43-E45 VanDerWaalsContact C-N 3.29Å; D43-E45 WeakPolarHBondContact OD1-CB 3.47Å; D43-E45 PolarHBondContact OD1-N 3.45Å; D43-E45 VanDerWaalsContact OD1-N 3.1Å
46R61.5Low84.4Confident188 Ų18872.2 Ų72.271%0.70935%0.345SS*.THydrogen-bonded Turntrans-107.6-2.6-175.4-62.1-173173.3-160.2-2.9114.4D43 R48D43-R46 HydrophobicContact CB-CB 4.41Å; D43-R46 PolarHBondContact O-N 2.95Å; D43-R46 PolarHBondContact OD1-N 2.94Å; D43-R46 WeakPolarHBondContact OD2-CD 3.3Å; D43-R46 WeakPolarHBondContact OD2-CG 3.49Å; R46-R48 HydrophobicContact CB-CB 4.5Å; R46-R48 WeakPolarHBondContact O-CG 3.43Å; R46-R48 PolarHBondContact O-N 2.89Å
47G67.7Low84.4Confident40 Ų4070.2 Ų70.241%0.41234%0.338SS..THydrogen-bonded Turntrans57.231.6-176.800000113.3D43D43-G47 PolarHBondContact O-N 2.83Å
48R74.6Confident84.3Confident183 Ų18370.3 Ų70.369%0.69134%0.339SS*.EExtended strand (participates in β ladder)trans-127145-170.4-77.8175.5-171.2-169.93.8112.8D43 R46 G50D43-R48 PolarHBondContact N-O 3.01Å; D43-R48 VanDerWaalsContact N-O 3.08Å; D43-R48 PolarHBondContact O-N 3Å; R46-R48 HydrophobicContact CB-CB 4.5Å; R46-R48 WeakPolarHBondContact O-CG 3.43Å; R46-R48 PolarHBondContact O-N 2.89Å; R48-G50 PolarHBondContact O-N 3.22Å
49R80.9Confident84.1Confident144 Ų14476.2 Ų76.254%0.54337%0.366SS..EExtended strand (participates in β ladder)trans-64.4119.8171.4-177.1178.974.9-174.8-3.3110.3L29 Y40L29-R49 HydrophobicContact CD2-CB 3.92Å; L29-R49 HydrophobicContact CD2-CG 3.94Å; Y40-R49 HydrophobicContact CD1-CG 3.66Å; Y40-R49 HydrophobicContact CD2-CG 4.27Å; Y40-R49 HydrophobicContact CE1-CG 4.37Å; Y40-R49 HydrophobicContact CG-CG 3.62Å
50G82.4Confident84.1Confident33 Ų3379.2 Ų79.234%0.3438%0.379SS..EExtended strand (participates in β ladder)trans-85.1-152.9173.500000113.3E41 R48E41-G50 WeakPolarHBondContact O-CA 3.38Å; E41-G50 PolarHBondContact O-N 2.89Å; R48-G50 PolarHBondContact O-N 3.22Å
51S87.5Confident84.2Confident56 Ų5677.8 Ų77.839%0.39237%0.374SS..EExtended strand (participates in β ladder)trans-65.7142.6-176.471.50000113Y40 E41 K53Y40-S51 WeakPolarHBondContact CA-O 3.37Å; E41-S51 PolarHBondContact N-O 3.07Å; E41-S51 PolarHBondContact OE2-OG 2.84Å; S51-K53 PolarHBondContact O-N 2.89Å; S51-K53 WeakPolarHBondContact OG-CE 3.4Å; S51-K53 PolarHBondContact OG-NZ 3.42Å
52K92.3Very high84.3Confident106 Ų10675.6 Ų75.646%0.46137%0.366SS..EExtended strand (participates in β ladder)trans-67.1128.7174.2-171.8179.3176.3-174.10109.7Y40 G54 S55Y40-K52 VanDerWaalsContact CD1-CA 3.45Å; Y40-K52 HydrophobicContact CD1-CB 3.72Å; Y40-K52 HydrophobicContact CD1-CG 4.13Å; Y40-K52 HydrophobicContact CE1-CB 3.59Å; Y40-K52 HydrophobicContact CE1-CD 4.27Å; Y40-K52 HydrophobicContact CE1-CG 3.77Å; K52-G54 WeakPolarHBondContact CE-O 3.43Å; K52-S55 WeakPolarHBondContact CE-OG 3.38Å; K52-S55 PolarHBondContact NZ-OG 3.03Å
53K93Very high84.9Confident89 Ų8973.5 Ų73.539%0.38736%0.358SS..EExtended strand (participates in β ladder)trans-105.5-18.5179.3-66.2-52.5-172.6-164.60114.4Y39 E41 S51Y39-K53 HydrophobicContact CD2-CB 3.83Å; Y39-K53 VanDerWaalsContact CE2-C 3.48Å; Y39-K53 HydrophobicContact CE2-CB 3.86Å; Y39-K53 PolarHBondContact O-N 2.99Å; E41-K53 HydrophobicContact CG-CG 4.26Å; E41-K53 WeakPolarHBondContact OE1-CE 3.24Å; E41-K53 IonicContact OE1-NZ 2.69Å; E41-K53 PolarHBondContact OE1-NZ 3.4Å; E41-K53 WeakPolarHBondContact OE2-CE 3.45Å; E41-K53 IonicContact OE2-NZ 3.61Å; E41-K53 PolarHBondContact OE2-NZ 3.06Å; S51-K53 PolarHBondContact O-N 2.89Å; S51-K53 WeakPolarHBondContact OG-CE 3.4Å; S51-K53 PolarHBondContact OG-NZ 3.42Å
54G91.6Very high85.7Confident18 Ų1870.6 Ų70.619%0.18634%0.342CS..EExtended strand (participates in β ladder)trans174.3175.1172.300000112.2Y39 K52Y39-G54 VanDerWaalsContact CZ-CA 3.49Å; Y39-G54 PolarHBondContact N-O 3.35Å; Y39-G54 PolarHBondContact O-N 3.45Å; K52-G54 WeakPolarHBondContact CE-O 3.43Å
55S94.3Very high87Confident46 Ų4667.6 Ų67.632%0.32233%0.329SS..EExtended strand (participates in β ladder)trans-155.9148.2173.750.40000110.6L37 S38 K52L37-S55 CarbonylContact O-C 3.55Å; L37-S55 VanDerWaalsContact O-CA 3.23Å; L37-S55 WeakPolarHBondContact O-CA 3.28Å; S38-S55 WeakPolarHBondContact OG-CB 3.45Å; K52-S55 WeakPolarHBondContact CE-OG 3.38Å; K52-S55 PolarHBondContact NZ-OG 3.03Å
56I94.3Very high88.5Confident4 Ų461.2 Ų61.22%0.02130%0.303CS..EExtended strand (participates in β ladder)trans-113.7131.2171.4-59.9168.2000106.6K36 L37 I61 V104 Y106 L111K36-I56 CarbonylContact C-O 3.57Å; K36-I56 WeakPolarHBondContact CA-O 3.47Å; L37-I56 HydrophobicContact CB-CB 4.46Å; L37-I56 PolarHBondContact N-O 2.68Å; L37-I56 PolarHBondContact O-N 3.06Å; I56-I61 HydrophobicContact CG2-CD1 4.33Å; I56-I61 HydrophobicContact CG2-CG1 3.84Å; I56-V104 HydrophobicContact CD1-CG1 4.49Å; I56-Y106 HydrophobicContact CD1-CD1 3.78Å; I56-Y106 HydrophobicContact CD1-CE1 3.54Å; I56-Y106 HydrophobicContact CD1-CG 4.36Å; I56-Y106 HydrophobicContact CG1-CD1 4.36Å; I56-Y106 HydrophobicContact CG1-CD2 4.4Å; I56-Y106 HydrophobicContact CG1-CE1 4.06Å; I56-Y106 HydrophobicContact CG1-CE2 4.16Å; I56-Y106 HydrophobicContact CG2-CD1 4.33Å; I56-Y106 HydrophobicContact CG2-CD2 3.87Å; I56-Y106 HydrophobicContact CG2-CE2 4.42Å; I56-Y106 HydrophobicContact CG2-CG 3.86Å; I56-L111 HydrophobicContact CD1-CB 4.24Å; I56-L111 HydrophobicContact CD1-CD2 3.58Å
57D94.4Very high90.1Very high44 Ų4452.5 Ų52.524%0.23527%0.27CS..EExtended strand (participates in β ladder)trans-73.8129.4172.2-61.6-42.1000108.6K36 E59 K60K36-D57 WeakPolarHBondContact CE-OD1 3.5Å; K36-D57 WeakPolarHBondContact CG-OD1 3.38Å; K36-D57 IonicContact NZ-OD1 2.79Å; K36-D57 PolarHBondContact NZ-OD1 2.74Å; D57-E59 HydrophobicContact CB-CG 4.15Å; D57-E59 PolarHBondContact O-N 2.86Å; D57-K60 HydrophobicContact CB-CD 4.2Å; D57-K60 HydrophobicContact CB-CG 4.21Å; D57-K60 WeakPolarHBondContact O-CB 3.39Å; D57-K60 PolarHBondContact O-N 2.82Å
58V93.9Very high91.2Very high5 Ų554.3 Ų54.33%0.0327%0.274CS..G310 helixtrans-61.7-34.6-171.7163.80000111.6L32 H35 K60 I61 V131 I132 N135L32-V58 HydrophobicContact CD1-CG2 4.14Å; H35-V58 WeakPolarHBondContact O-CB 3.3Å; H35-V58 PolarHBondContact O-N 3.33Å; V58-K60 PolarHBondContact O-N 2.84Å; V58-I61 HydrophobicContact CG2-CD1 4.38Å; V58-I61 WeakPolarHBondContact O-CB 3.43Å; V58-I61 PolarHBondContact O-N 2.83Å; V58-I61 VanDerWaalsContact O-N 3.09Å; V58-V131 HydrophobicContact CG1-CB 4.49Å; V58-V131 HydrophobicContact CG1-CG1 3.47Å; V58-V131 VanDerWaalsContact CG1-CG1 3.47Å; V58-I132 HydrophobicContact CG1-CG2 4.09Å; V58-N135 PolarHBondContact O-ND2 2.98Å
59E92.9Very high91.9Very high134 Ų13448.1 Ų48.163%0.62626%0.257SS*.G310 helixtrans-58.9-26.8175.668-170.517800113.4D57 I61 N135D57-E59 HydrophobicContact CB-CG 4.15Å; D57-E59 PolarHBondContact O-N 2.86Å; E59-I61 VanDerWaalsContact C-N 3.34Å; E59-N135 PolarHBondContact O-ND2 3.46Å
60K93.1Very high92.1Very high87 Ų8743.3 Ų43.338%0.37824%0.241SC..G310 helixtrans-85.5-8180-61.7-176.9163.5-152.60113.4D57 V58 T62 Y106 D107D57-K60 HydrophobicContact CB-CD 4.2Å; D57-K60 HydrophobicContact CB-CG 4.21Å; D57-K60 WeakPolarHBondContact O-CB 3.39Å; D57-K60 PolarHBondContact O-N 2.82Å; V58-K60 PolarHBondContact O-N 2.84Å; K60-T62 PolarHBondContact O-N 3.49Å; K60-Y106 WeakPolarHBondContact O-CA 3.43Å; K60-Y106 VanDerWaalsContact O-CB 3.31Å; K60-Y106 WeakPolarHBondContact O-CB 3.39Å; K60-D107 WeakPolarHBondContact CD-OD2 3.49Å; K60-D107 IonicContact NZ-OD2 2.87Å; K60-D107 PolarHBondContact NZ-OD2 3.3Å
61I94.6Very high91.9Very high1 Ų151.3 Ų51.31%0.00527%0.266CS..  trans-77.5123-179.3-59.3174.9000108.2I56 V58 E59 V64 V104 V105 L128 I132 N135I56-I61 HydrophobicContact CG2-CD1 4.33Å; I56-I61 HydrophobicContact CG2-CG1 3.84Å; V58-I61 HydrophobicContact CG2-CD1 4.38Å; V58-I61 WeakPolarHBondContact O-CB 3.43Å; V58-I61 PolarHBondContact O-N 2.83Å; V58-I61 VanDerWaalsContact O-N 3.09Å; E59-I61 VanDerWaalsContact C-N 3.34Å; I61-V64 HydrophobicContact CG2-CG2 3.66Å; I61-V104 HydrophobicContact CD1-CG1 3.87Å; I61-V104 HydrophobicContact CG1-CG1 3.99Å; I61-V104 HydrophobicContact CG2-CG1 3.89Å; I61-V105 WeakPolarHBondContact CA-O 3.48Å; I61-L128 HydrophobicContact CD1-CD2 4.43Å; I61-I132 HydrophobicContact CB-CG2 3.8Å; I61-I132 HydrophobicContact CD1-CG2 4.36Å; I61-I132 HydrophobicContact CG2-CD1 4.06Å; I61-I132 HydrophobicContact CG2-CG2 3.88Å; I61-N135 PolarHBondContact O-ND2 2.9Å
62T92.4Very high91.7Very high28 Ų2856.1 Ų56.117%0.17229%0.287CS..  trans-103.8-24.8-176.461.30000112.7K60 V105 D137 V139K60-T62 PolarHBondContact O-N 3.49Å; T62-V105 PolarHBondContact N-O 2.81Å; T62-V105 PolarHBondContact OG1-O 2.94Å; T62-D137 VanDerWaalsContact CB-O 3.26Å; T62-D137 WeakPolarHBondContact CB-O 3.35Å; T62-D137 HydrophobicContact CG2-CB 4.18Å; T62-D137 WeakPolarHBondContact CG2-O 3.46Å; T62-V139 PolarHBondContact O-N 3.03Å; T62-V139 VanDerWaalsContact O-N 3.15Å
63C92.2Very high91.4Very high3 Ų352.1 Ų52.12%0.0227%0.272CS..EExtended strand (participates in β ladder)trans-158.2144.5177.3174.50000112V105 V139C63-V105 HydrophobicContact CB-CB 4.08Å; C63-V105 HydrophobicContact CB-CG2 4.15Å; C63-V105 PolarHBondContact O-N 2.84Å; C63-V139 HydrophobicContact CB-CG2 3.52Å
64V95.3Very high90.9Very high2 Ų250.2 Ų50.21%0.01227%0.269CS..EExtended strand (participates in β ladder)trans-134.3123168.8-179.70000109.1I61 F102 Q103 V104 I125 L128 K129 I132I61-V64 HydrophobicContact CG2-CG2 3.66Å; V64-F102 HydrophobicContact CG1-CD2 4.44Å; V64-Q103 WeakPolarHBondContact CA-O 3.48Å; V64-V104 HydrophobicContact CG1-CG2 4.46Å; V64-V104 HydrophobicContact CG2-CB 4.47Å; V64-V104 HydrophobicContact CG2-CG1 4.18Å; V64-V104 HydrophobicContact CG2-CG2 4.25Å; V64-I125 HydrophobicContact CG1-CB 4.43Å; V64-I125 HydrophobicContact CG1-CG1 4.16Å; V64-I125 HydrophobicContact CG1-CG2 4.36Å; V64-L128 HydrophobicContact CB-CB 4.17Å; V64-L128 HydrophobicContact CG1-CB 3.97Å; V64-L128 HydrophobicContact CG1-CD1 3.77Å; V64-L128 HydrophobicContact CG2-CB 3.92Å; V64-L128 HydrophobicContact CG2-CD1 4.24Å; V64-K129 WeakPolarHBondContact O-CE 3.25Å; V64-I132 HydrophobicContact CG2-CD1 4.24Å
65E95.4Very high90.4Very high27 Ų2753.9 Ų53.913%0.12629%0.29CS..EExtended strand (participates in β ladder)trans-154.8165.9-178-163.442.9-95.600112.1F102 Q103 K129 Y142 L168E65-F102 CarbonylContact O-C 3.59Å; E65-F102 WeakPolarHBondContact O-CA 3.42Å; E65-F102 WeakPolarHBondContact O-CB 3.5Å; E65-Q103 PolarHBondContact N-O 2.8Å; E65-Q103 WeakPolarHBondContact O-CG 3.35Å; E65-Q103 PolarHBondContact O-N 2.81Å; E65-K129 WeakPolarHBondContact OE2-CE 3.5Å; E65-K129 IonicContact OE2-NZ 2.69Å; E65-K129 PolarHBondContact OE2-NZ 3.22Å; E65-Y142 HydrophobicContact CB-CD2 3.79Å; E65-Y142 HydrophobicContact CB-CE2 3.81Å; E65-Y142 HydrophobicContact CB-CG 4.35Å; E65-Y142 HydrophobicContact CG-CD2 3.79Å; E65-Y142 HydrophobicContact CG-CE1 4.1Å; E65-Y142 HydrophobicContact CG-CE2 3.29Å; E65-Y142 HydrophobicContact CG-CG 4.36Å; E65-Y142 VanDerWaalsContact CG-CZ 3.47Å; E65-L168 HydrophobicContact CB-CD2 4.47Å; E65-L168 HydrophobicContact CG-CD2 4.3Å
66T95Very high89.7Confident48 Ų4855.4 Ų55.429%0.29429%0.292SS..EExtended strand (participates in β ladder)trans-61.3158.4169.955.60000112Q103 I125T66-Q103 PolarHBondContact O-NE2 3.45Å; T66-I125 HydrophobicContact CG2-CD1 3.48Å; T66-I125 VanDerWaalsContact CG2-CD1 3.48Å
67V94.4Very high89.3Confident4 Ų456.2 Ų56.22%0.02429%0.294CS..  trans-124.2141.8172.9-176.70000108.1P69 P101 Q103 Y112 P144 F146V67-P69 WeakPolarHBondContact O-CD 3.17Å; V67-P101 HydrophobicContact CB-CB 4.14Å; V67-P101 HydrophobicContact CB-CG 4.25Å; V67-P101 PolarHBondContact N-O 2.94Å; V67-P101 WeakPolarHBondContact O-CG 3.43Å; V67-Q103 HydrophobicContact CG2-CB 3.65Å; V67-Q103 HydrophobicContact CG2-CG 3.9Å; V67-Y112 HydrophobicContact CG1-CE1 4.47Å; V67-Y112 HydrophobicContact CG2-CD1 3.99Å; V67-Y112 HydrophobicContact CG2-CE1 4.07Å; V67-P144 CarbonylContact C-O 3.56Å; V67-P144 WeakPolarHBondContact CA-O 3.14Å; V67-F146 HydrophobicContact CB-CE1 4.4Å; V67-F146 HydrophobicContact CB-CZ 4.35Å; V67-F146 HydrophobicContact CG1-CD1 3.79Å; V67-F146 HydrophobicContact CG1-CD2 3.91Å; V67-F146 HydrophobicContact CG1-CE1 3.7Å; V67-F146 HydrophobicContact CG1-CE2 3.79Å; V67-F146 HydrophobicContact CG1-CG 3.91Å; V67-F146 HydrophobicContact CG1-CZ 3.7Å
68V91.4Very high88.7Confident79 Ų7958.8 Ų58.848%0.47931%0.305SS..PPolyproline II helixtrans-61.9123.3173.31780000108.8P144 F146V68-P144 HydrophobicContact CG2-CB 4.34Å; V68-P144 WeakPolarHBondContact CG2-O 2.89Å; V68-P144 PolarHBondContact N-O 3.37Å; V68-F146 WeakPolarHBondContact O-CE2 3.42Å
69P88.6Confident88Confident53 Ų5362.9 Ų62.934%0.34433%0.326SS..PPolyproline II helixtrans-56.2153.3178.4-25.634.6000113V67 I79 P101V67-P69 WeakPolarHBondContact O-CD 3.17Å; P69-I79 HydrophobicContact CG-CD1 4.35Å; P69-P101 HydrophobicContact CG-CG 4.43Å
70E84.7Confident86.8Confident43 Ų4358.8 Ų58.820%0.20131%0.311CS..PPolyproline II helixtrans-61.7144.2173.9-57.2-179.8131.500109.5N72 P73 R77 F146E70-N72 VanDerWaalsContact C-N 3.35Å; E70-N72 PolarHBondContact O-N 3.3Å; E70-P73 HydrophobicContact CB-CB 4.31Å; E70-P73 WeakPolarHBondContact O-CD 3.48Å; E70-R77 IonicContact OE2-CZ 2.84Å; E70-R77 IonicContact OE2-NE 3.73Å; E70-R77 PolarHBondContact OE2-NE 2.92Å; E70-R77 IonicContact OE2-NH2 2.9Å; E70-R77 PolarHBondContact OE2-NH2 3.03Å; E70-F146 HydrophobicContact CG-CD2 3.99Å; E70-F146 HydrophobicContact CG-CE2 3.62Å; E70-F146 HydrophobicContact CG-CZ 4.45Å
71K79.2Confident85.5Confident201 Ų20164.4 Ų64.487%0.87433%0.33SS*.SBendtrans-64.1-40.9-179.8-68.8-175.2178.8-178.20112.1
72N83.4Confident83.5Confident156 Ų15676.8 Ų76.883%0.83438%0.376SS*.SBendtrans-130.172.6-177-63.9-13.9000110.6E70E70-N72 VanDerWaalsContact C-N 3.35Å; E70-N72 PolarHBondContact O-N 3.3Å
73P84.9Confident81.7Confident22 Ų2279.2 Ų79.214%0.14341%0.407CS..  trans-76.6154.5178.527.8-25.6000111.5E70 R77 Q78E70-P73 HydrophobicContact CB-CB 4.31Å; E70-P73 WeakPolarHBondContact O-CD 3.48Å; P73-R77 HydrophobicContact CB-CB 3.82Å; P73-R77 WeakPolarHBondContact CG-O 3.46Å; P73-Q78 HydrophobicContact CG-CG 3.89Å; P73-Q78 WeakPolarHBondContact O-CG 3.35Å; P73-Q78 PolarHBondContact O-NE2 2.91Å
74P82.9Confident79.7Confident50 Ų5086.3 Ų86.333%0.32544%0.44SS..  trans-63.3162.7169.428.7-34000111.1E76 R77 Q78P74-E76 HydrophobicContact CB-CG 4.16Å; P74-E76 HydrophobicContact CG-CG 3.9Å; P74-E76 PolarHBondContact O-N 3.31Å; P74-E76 VanDerWaalsContact O-N 3.08Å; P74-R77 VanDerWaalsContact CD-CZ 3.42Å; P74-R77 VanDerWaalsContact CG-NH1 3.27Å; P74-R77 PolarHBondContact O-N 3.06Å; P74-Q78 PolarHBondContact O-N 2.83Å
75P80.4Confident77.4Confident95 Ų9590.2 Ų90.262%0.61746%0.458SS*.G310 helixtrans-51.9-36.8-174-28.935.6000114.7R77 Q78P75-R77 PolarHBondContact O-N 3.26Å; P75-R77 VanDerWaalsContact O-N 3.09Å; P75-Q78 PolarHBondContact O-N 2.99Å
76E81.3Confident75.3Confident78 Ų7892 Ų9236%0.36447%0.474SS..G310 helixtrans-61.4-14175.652.2161.5-142.900114.6P74 R97 F98P74-E76 HydrophobicContact CB-CG 4.16Å; P74-E76 HydrophobicContact CG-CG 3.9Å; P74-E76 PolarHBondContact O-N 3.31Å; P74-E76 VanDerWaalsContact O-N 3.08Å; E76-R97 CarbonylContact O-C 3.49Å; E76-R97 WeakPolarHBondContact O-CA 3.11Å; E76-F98 PolarHBondContact O-N 2.97Å
77R84.5Confident73.3Confident20 Ų2094.5 Ų94.58%0.07549%0.493CS..G310 helixtrans-128.811.4-179.5-60.5-167.8-55.9-89.310.5113.1L11 E70 P73 P74 P75 P99 F114L11-R77 HydrophobicContact CD2-CG 3.91Å; E70-R77 IonicContact OE2-CZ 2.84Å; E70-R77 IonicContact OE2-NE 3.73Å; E70-R77 PolarHBondContact OE2-NE 2.92Å; E70-R77 IonicContact OE2-NH2 2.9Å; E70-R77 PolarHBondContact OE2-NH2 3.03Å; P73-R77 HydrophobicContact CB-CB 3.82Å; P73-R77 WeakPolarHBondContact CG-O 3.46Å; P74-R77 VanDerWaalsContact CD-CZ 3.42Å; P74-R77 VanDerWaalsContact CG-NH1 3.27Å; P74-R77 PolarHBondContact O-N 3.06Å; P75-R77 PolarHBondContact O-N 3.26Å; P75-R77 VanDerWaalsContact O-N 3.09Å; R77-P99 WeakPolarHBondContact O-CA 3.25Å; R77-P99 WeakPolarHBondContact O-CB 3.48Å; R77-F114 HydrophobicContact CG-CD1 4.47Å
78Q83.3Confident71.1Confident99 Ų99101.8 Ų101.846%0.46353%0.527SS..PPolyproline II helixtrans-79134.8174.4-76.9174.913.500110.5P73 P74 P75 P80 P99P73-Q78 HydrophobicContact CG-CG 3.89Å; P73-Q78 WeakPolarHBondContact O-CG 3.35Å; P73-Q78 PolarHBondContact O-NE2 2.91Å; P74-Q78 PolarHBondContact O-N 2.83Å; P75-Q78 PolarHBondContact O-N 2.99Å; Q78-P80 WeakPolarHBondContact O-CD 3.21Å; Q78-P99 WeakPolarHBondContact O-CB 3.37Å
79I78.3Confident69.1Low90 Ų90103.4 Ų103.446%0.46253%0.53SS..PPolyproline II helixtrans-70.2123.8174.3-60.1167.8000107.5P69 P99 Y100P69-I79 HydrophobicContact CG-CD1 4.35Å; I79-P99 HydrophobicContact CB-CB 4.4Å; I79-P99 HydrophobicContact CG1-CB 3.8Å; I79-Y100 HydrophobicContact CG1-CE1 4.44Å; I79-Y100 HydrophobicContact CG2-CE1 4.42Å
80P67.8Low67.6Low48 Ų48105.8 Ų105.831%0.31254%0.537SS..PPolyproline II helixtrans-63.3146.8179.322.2-29.3000111.6Q78 E85Q78-P80 WeakPolarHBondContact O-CD 3.21Å; P80-E85 WeakPolarHBondContact CB-OE1 3.5Å
81R66.1Low66Low205 Ų205110.4 Ų110.477%0.77456%0.559SS**PPolyproline II helixtrans-75.3136.5175.8-67.8-178.9177.9-179.90108.8G83R81-G83 PolarHBondContact O-N 3.22Å; R81-G83 VanDerWaalsContact O-N 3.11Å
82R52.2Low64.8Low261 Ų261105.3 Ų105.399%0.98554%0.54SS*.THydrogen-bonded Turntrans-56.9116.4177.1-88.1-175.5175.9-175.1-1.7109.9
83G54.3Low63.5Low80 Ų8098.8 Ų98.883%0.82551%0.507SS*.THydrogen-bonded Turntrans123.93.2168.300000117.7R81R81-G83 PolarHBondContact O-N 3.22Å; R81-G83 VanDerWaalsContact O-N 3.11Å
84E50.1Low62.4Low151 Ų151100.3 Ų100.371%0.70651%0.513SS*.  trans-114.323.8-173.6-73.4-175.9169.400115.6
85E46.9Very low61.6Low84 Ų84101.6 Ų101.639%0.39352%0.516SS..  trans-121.4114.2-175.3-67-176.7173.500112.5P80 R97P80-E85 WeakPolarHBondContact CB-OE1 3.5Å; E85-R97 IonicContact OE1-NH1 2.82Å
86S51.4Low61.2Low65 Ų65102.4 Ų102.446%0.45551%0.512SS..  trans-77.8156.6160.761.90000110E88 M89 E90S86-E88 PolarHBondContact O-N 3.35Å; S86-E88 VanDerWaalsContact O-N 3.09Å; S86-M89 PolarHBondContact O-N 3.14Å; S86-E90 PolarHBondContact O-N 3.2Å; S86-E90 VanDerWaalsContact O-N 3.14Å
87S53Low61.3Low100 Ų100104 Ų10470%0.69951%0.514SS*.Hα-helixtrans-53.8-30.7-177.4174.80000114.8
88E47.7Very low61.5Low158 Ų158103.1 Ų103.174%0.73851%0.511SS*.Hα-helixtrans-80.1-33.2178.8-66.9179.5154.700112.2S86 E90S86-E88 PolarHBondContact O-N 3.35Å; S86-E88 VanDerWaalsContact O-N 3.09Å; E88-E90 VanDerWaalsContact C-N 3.33Å
89M50.8Low61.8Low112 Ų11298.6 Ų98.655%0.55249%0.49SS*.Hα-helixtrans-69.3-32174.1-83179.3139.900111.9S86 I92 S93S86-M89 PolarHBondContact O-N 3.14Å; M89-I92 PolarHBondContact O-N 3.5Å; M89-S93 WeakPolarHBondContact O-CB 3.49Å; M89-S93 PolarHBondContact O-N 2.72Å; M89-S93 PolarHBondContact O-OG 3.22Å
90E55.5Low62.5Low104 Ų10496.5 Ų96.549%0.48648%0.477SS..Hα-helixtrans-61.9-44178.4-162.1172.2-175.500111.1S86 E88 S93 I94S86-E90 PolarHBondContact O-N 3.2Å; S86-E90 VanDerWaalsContact O-N 3.14Å; E88-E90 VanDerWaalsContact C-N 3.33Å; E90-S93 PolarHBondContact O-N 2.7Å; E90-S93 PolarHBondContact O-OG 2.93Å; E90-I94 HydrophobicContact CG-CD1 4.36Å; E90-I94 WeakPolarHBondContact O-CD1 2.97Å; E90-I94 VanDerWaalsContact O-CG1 3.27Å; E90-I94 WeakPolarHBondContact O-CG1 3.47Å; E90-I94 PolarHBondContact O-N 3.12Å; E90-I94 VanDerWaalsContact O-N 3.11Å
91Q51.9Low63.8Low140 Ų14094.2 Ų94.265%0.65446%0.462SS*.Hα-helixtrans-67.4-39.7179.7-158.8169.420.300112.9
92I53.5Low65.3Low94 Ų9484.6 Ų84.648%0.48243%0.426SS..Hα-helixtrans-69.1-39174.6-62.4171.2000110.7M89 I94 I95 E96M89-I92 PolarHBondContact O-N 3.5Å; I92-I94 VanDerWaalsContact C-N 3.33Å; I92-I94 PolarHBondContact O-N 3.48Å; I92-I95 WeakPolarHBondContact O-CG1 3.4Å; I92-I95 PolarHBondContact O-N 3.05Å; I92-E96 PolarHBondContact O-N 3.32Å
93S57.7Low67.4Low19 Ų1972.2 Ų72.213%0.13338%0.379CS..Hα-helixtrans-63.8-36.2179.980.20000112.7M89 E90 I95 E96 R97M89-S93 WeakPolarHBondContact O-CB 3.49Å; M89-S93 PolarHBondContact O-N 2.72Å; M89-S93 PolarHBondContact O-OG 3.22Å; E90-S93 PolarHBondContact O-N 2.7Å; E90-S93 PolarHBondContact O-OG 2.93Å; S93-I95 VanDerWaalsContact C-N 3.25Å; S93-I95 PolarHBondContact O-N 3.21Å; S93-E96 PolarHBondContact O-N 3.06Å; S93-R97 WeakPolarHBondContact O-CB 3.44Å; S93-R97 PolarHBondContact O-N 3.1Å
94I60.9Low69.4Low54 Ų5468.4 Ų68.428%0.27734%0.34SS..Hα-helixtrans-65.7-26.5-177.6-73.4164.8000112.6E90 I92 P116 T117E90-I94 HydrophobicContact CG-CD1 4.36Å; E90-I94 WeakPolarHBondContact O-CD1 2.97Å; E90-I94 VanDerWaalsContact O-CG1 3.27Å; E90-I94 WeakPolarHBondContact O-CG1 3.47Å; E90-I94 PolarHBondContact O-N 3.12Å; E90-I94 VanDerWaalsContact O-N 3.11Å; I92-I94 VanDerWaalsContact C-N 3.33Å; I92-I94 PolarHBondContact O-N 3.48Å; I94-P116 HydrophobicContact CG2-CB 4.35Å; I94-P116 HydrophobicContact CG2-CG 4.31Å; I94-P116 WeakPolarHBondContact O-CB 3.44Å; I94-T117 HydrophobicContact CG1-CG2 4.22Å
95I65.6Low71.4Confident76 Ų7662.6 Ų62.639%0.3932%0.315SS..Hα-helixtrans-99.7-15.6179.953168.7000113.5K27 I92 S93 F98K27-I95 WeakPolarHBondContact CE-O 3.48Å; K27-I95 PolarHBondContact NZ-O 3Å; I92-I95 WeakPolarHBondContact O-CG1 3.4Å; I92-I95 PolarHBondContact O-N 3.05Å; S93-I95 VanDerWaalsContact C-N 3.25Å; S93-I95 PolarHBondContact O-N 3.21Å; I95-F98 WeakPolarHBondContact O-CE2 3.45Å
96E72.4Confident73.6Confident112 Ų11259.5 Ų59.552%0.52330%0.3SS..Hα-helixtrans-112.5-28.1-176.6-64.2-162.8151.200115.1I92 S93I92-E96 PolarHBondContact O-N 3.32Å; S93-E96 PolarHBondContact O-N 3.06Å
97R83.1Confident75.1Confident112 Ų11261 Ų6142%0.42330%0.302SS..  trans-110.7133.7-178.1-62.3-178.8-177.6165.2-1.4111.3E76 E85 S93 P116E76-R97 CarbonylContact O-C 3.49Å; E76-R97 WeakPolarHBondContact O-CA 3.11Å; E85-R97 IonicContact OE1-NH1 2.82Å; S93-R97 WeakPolarHBondContact O-CB 3.44Å; S93-R97 PolarHBondContact O-N 3.1Å; R97-P116 VanDerWaalsContact O-CA 3.26Å; R97-P116 WeakPolarHBondContact O-CA 3.31Å; R97-P116 WeakPolarHBondContact O-CB 3.43Å
98F89.7Confident76.6Confident1 Ų161 Ų610%0.00429%0.292CS..  trans-134.772.4-178.1-59.6-90.9000111.2I9 L11 K27 E76 I95 F114 S115 P116I9-F98 HydrophobicContact CG2-CE1 4.45Å; I9-F98 HydrophobicContact CG2-CZ 4.25Å; L11-F98 HydrophobicContact CB-CB 3.7Å; L11-F98 HydrophobicContact CB-CD1 4.06Å; L11-F98 HydrophobicContact CB-CD2 3.77Å; L11-F98 HydrophobicContact CB-CE2 4.45Å; L11-F98 HydrophobicContact CB-CG 3.56Å; L11-F98 HydrophobicContact CD2-CB 4.17Å; L11-F98 HydrophobicContact CD2-CD2 4.39Å; K27-F98 HydrophobicContact CD-CE2 4.15Å; K27-F98 HydrophobicContact CD-CZ 4.41Å; K27-F98 HydrophobicContact CG-CE2 4.25Å; E76-F98 PolarHBondContact O-N 2.97Å; I95-F98 WeakPolarHBondContact O-CE2 3.45Å; F98-F114 HydrophobicContact CB-CB 3.76Å; F98-F114 WeakPolarHBondContact CD1-O 3.49Å; F98-F114 WeakPolarHBondContact O-CB 3.25Å; F98-F114 WeakPolarHBondContact O-CD1 3.14Å; F98-S115 CarbonylContact C-O 3.57Å; F98-S115 WeakPolarHBondContact CA-O 3.32Å; F98-P116 HydrophobicContact CD1-CB 4.22Å; F98-P116 HydrophobicContact CD1-CG 4.44Å; F98-P116 HydrophobicContact CE1-CB 4.31Å; F98-P116 HydrophobicContact CE1-CG 4.34Å
99P88.9Confident78.5Confident4 Ų453.9 Ų53.93%0.02626%0.26CS..  trans-88.7-8.7-170.834.9-34.8000114.5R77 Q78 I79 P101 S115R77-P99 WeakPolarHBondContact O-CA 3.25Å; R77-P99 WeakPolarHBondContact O-CB 3.48Å; Q78-P99 WeakPolarHBondContact O-CB 3.37Å; I79-P99 HydrophobicContact CB-CB 4.4Å; I79-P99 HydrophobicContact CG1-CB 3.8Å; P99-P101 WeakPolarHBondContact O-CD 3.45Å; P99-S115 WeakPolarHBondContact CD-O 3.39Å
100Y93.3Very high80.5Confident46 Ų4648.9 Ų48.918%0.1824%0.236CC..EExtended strand (participates in β ladder)trans-107.493.4-171-56.8-73000112.7I79 S115 P116 E118I79-Y100 HydrophobicContact CG1-CE1 4.44Å; I79-Y100 HydrophobicContact CG2-CE1 4.42Å; Y100-S115 PolarHBondContact N-O 3.44Å; Y100-S115 VanDerWaalsContact N-O 3.1Å; Y100-S115 WeakPolarHBondContact O-CB 3.43Å; Y100-S115 PolarHBondContact O-N 2.95Å; Y100-P116 WeakPolarHBondContact CD2-O 3.21Å; Y100-P116 VanDerWaalsContact CE2-O 3.26Å; Y100-P116 WeakPolarHBondContact CE2-O 3.49Å; Y100-E118 HydrophobicContact CD1-CB 4.06Å; Y100-E118 HydrophobicContact CE1-CB 3.97Å; Y100-E118 HydrophobicContact CE2-CB 4.41Å; Y100-E118 HydrophobicContact CG-CB 4.34Å
101P95.2Very high82.3Confident0 Ų044 Ų440%021%0.213CC..EExtended strand (participates in β ladder)trans-78.2150.7-17930.4-35.3000113.9V67 P69 P99 V113 F114 R121 F146V67-P101 HydrophobicContact CB-CB 4.14Å; V67-P101 HydrophobicContact CB-CG 4.25Å; V67-P101 PolarHBondContact N-O 2.94Å; V67-P101 WeakPolarHBondContact O-CG 3.43Å; P69-P101 HydrophobicContact CG-CG 4.43Å; P99-P101 WeakPolarHBondContact O-CD 3.45Å; P101-V113 CarbonylContact C-O 3.55Å; P101-V113 WeakPolarHBondContact CA-O 3.3Å; P101-F114 HydrophobicContact CB-CD1 3.71Å; P101-F114 HydrophobicContact CB-CE1 3.67Å; P101-F114 HydrophobicContact CB-CG 4.19Å; P101-F114 HydrophobicContact CB-CZ 4.08Å; P101-F114 HydrophobicContact CG-CD1 4.31Å; P101-F114 HydrophobicContact CG-CE1 4.15Å; P101-R121 VanDerWaalsContact O-CD 3.32Å; P101-R121 WeakPolarHBondContact O-CD 3.47Å; P101-R121 PolarHBondContact O-NH1 3.01Å; P101-F146 HydrophobicContact CB-CE1 4.31Å; P101-F146 HydrophobicContact CB-CZ 3.68Å; P101-F146 HydrophobicContact CG-CE2 4.44Å; P101-F146 HydrophobicContact CG-CZ 3.91Å
102F97Very high84.4Confident3 Ų337.7 Ų37.71%0.01318%0.184CC..EExtended strand (participates in β ladder)trans-144.6164.1165.669.7-82.4000110F10 V64 E65 V104 V113 R121 W124 I125 L128F10-F102 HydrophobicContact CD2-CZ 4.39Å; F10-F102 HydrophobicContact CE1-CE1 4.43Å; F10-F102 HydrophobicContact CE2-CE1 4.32Å; F10-F102 HydrophobicContact CE2-CZ 4.07Å; F10-F102 HydrophobicContact CZ-CE1 4.23Å; F10-F102 HydrophobicContact CZ-CZ 4.35Å; V64-F102 HydrophobicContact CG1-CD2 4.44Å; E65-F102 CarbonylContact O-C 3.59Å; E65-F102 WeakPolarHBondContact O-CA 3.42Å; E65-F102 WeakPolarHBondContact O-CB 3.5Å; F102-V104 HydrophobicContact CD2-CG2 4.39Å; F102-V104 HydrophobicContact CE2-CG2 4.07Å; F102-V113 HydrophobicContact CD1-CB 4.16Å; F102-V113 HydrophobicContact CD1-CG1 4.45Å; F102-V113 WeakPolarHBondContact CD1-O 3.47Å; F102-V113 HydrophobicContact CE1-CB 3.65Å; F102-V113 HydrophobicContact CE1-CG1 3.54Å; F102-V113 HydrophobicContact CE2-CB 4.02Å; F102-V113 HydrophobicContact CE2-CG1 4.41Å; F102-V113 HydrophobicContact CE2-CG2 4.42Å; F102-V113 HydrophobicContact CZ-CB 3.57Å; F102-V113 HydrophobicContact CZ-CG1 3.52Å; F102-V113 HydrophobicContact CZ-CG2 4.28Å; F102-V113 PolarHBondContact N-O 2.69Å; F102-V113 PolarHBondContact O-N 2.61Å; F102-V113 VanDerWaalsContact O-O 3.09Å; F102-R121 HydrophobicContact CB-CG 4.14Å; F102-R121 HydrophobicContact CD1-CG 4.08Å; F102-R121 HydrophobicContact CG-CG 4.41Å; F102-W124 HydrophobicContact CZ-CB 4.47Å; F102-I125 HydrophobicContact CB-CD1 3.84Å; F102-I125 HydrophobicContact CB-CG1 4.11Å; F102-I125 HydrophobicContact CD2-CG1 4.32Å; F102-I125 HydrophobicContact CG-CG1 4.33Å; F102-L128 HydrophobicContact CE2-CD1 4.29Å
103Q95.8Very high86.4Confident1 Ų133.3 Ų33.31%0.00516%0.161CC..EExtended strand (participates in β ladder)trans-121.4145-178.666.3-167.3-5900111.7V64 E65 T66 V67 V105 L111 Y112 H143V64-Q103 WeakPolarHBondContact CA-O 3.48Å; E65-Q103 PolarHBondContact N-O 2.8Å; E65-Q103 WeakPolarHBondContact O-CG 3.35Å; E65-Q103 PolarHBondContact O-N 2.81Å; T66-Q103 PolarHBondContact O-NE2 3.45Å; V67-Q103 HydrophobicContact CG2-CB 3.65Å; V67-Q103 HydrophobicContact CG2-CG 3.9Å; Q103-V105 HydrophobicContact CG-CG2 4.15Å; Q103-L111 CarbonylContact C-O 3.52Å; Q103-L111 WeakPolarHBondContact CA-O 3.36Å; Q103-Y112 HydrophobicContact CB-CD1 3.96Å; Q103-Y112 HydrophobicContact CB-CE1 4.03Å; Q103-H143 PolarHBondContact NE2-O 3Å; Q103-H143 PolarHBondContact OE1-O 2.98Å
104V95.9Very high88.2Confident0 Ų032.6 Ų32.60%016%0.155CC..EExtended strand (participates in β ladder)trans-117.1111.5167.6-178.30000107.5L37 I56 I61 V64 F102 L111 L128L37-V104 HydrophobicContact CD2-CG1 4.17Å; L37-V104 HydrophobicContact CD2-CG2 4.15Å; I56-V104 HydrophobicContact CD1-CG1 4.49Å; I61-V104 HydrophobicContact CD1-CG1 3.87Å; I61-V104 HydrophobicContact CG1-CG1 3.99Å; I61-V104 HydrophobicContact CG2-CG1 3.89Å; V64-V104 HydrophobicContact CG1-CG2 4.46Å; V64-V104 HydrophobicContact CG2-CB 4.47Å; V64-V104 HydrophobicContact CG2-CG1 4.18Å; V64-V104 HydrophobicContact CG2-CG2 4.25Å; F102-V104 HydrophobicContact CD2-CG2 4.39Å; F102-V104 HydrophobicContact CE2-CG2 4.07Å; V104-L111 HydrophobicContact CB-CB 4.37Å; V104-L111 PolarHBondContact N-O 3.39Å; V104-L111 PolarHBondContact O-N 3.08Å; V104-L128 HydrophobicContact CG2-CD1 4.17Å
105V93.6Very high89.7Confident29 Ų2930 Ų3018%0.17614%0.142CC..EExtended strand (participates in β ladder)trans-96.9129.9-176.1-1710000109.4I61 T62 C63 Q103 P110I61-V105 WeakPolarHBondContact CA-O 3.48Å; T62-V105 PolarHBondContact N-O 2.81Å; T62-V105 PolarHBondContact OG1-O 2.94Å; C63-V105 HydrophobicContact CB-CB 4.08Å; C63-V105 HydrophobicContact CB-CG2 4.15Å; C63-V105 PolarHBondContact O-N 2.84Å; Q103-V105 HydrophobicContact CG-CG2 4.15Å; V105-P110 HydrophobicContact CG2-CB 4.44Å
106Y92.3Very high90.7Very high19 Ų1927 Ų278%0.07513%0.128CC..EExtended strand (participates in β ladder)trans-152.5-175.3179.473.8-72.2000110Q15 I56 K60 E108 G109 L111Q15-Y106 VanDerWaalsContact NE2-CE1 3.32Å; Q15-Y106 PolarHBondContact NE2-OH 3.06Å; I56-Y106 HydrophobicContact CD1-CD1 3.78Å; I56-Y106 HydrophobicContact CD1-CE1 3.54Å; I56-Y106 HydrophobicContact CD1-CG 4.36Å; I56-Y106 HydrophobicContact CG1-CD1 4.36Å; I56-Y106 HydrophobicContact CG1-CD2 4.4Å; I56-Y106 HydrophobicContact CG1-CE1 4.06Å; I56-Y106 HydrophobicContact CG1-CE2 4.16Å; I56-Y106 HydrophobicContact CG2-CD1 4.33Å; I56-Y106 HydrophobicContact CG2-CD2 3.87Å; I56-Y106 HydrophobicContact CG2-CE2 4.42Å; I56-Y106 HydrophobicContact CG2-CG 3.86Å; K60-Y106 WeakPolarHBondContact O-CA 3.43Å; K60-Y106 VanDerWaalsContact O-CB 3.31Å; K60-Y106 WeakPolarHBondContact O-CB 3.39Å; Y106-E108 VanDerWaalsContact C-N 3.34Å; Y106-E108 HydrophobicContact CD2-CB 4.47Å; Y106-E108 HydrophobicContact CE2-CB 3.62Å; Y106-E108 HydrophobicContact CE2-CG 3.72Å; Y106-E108 PolarHBondContact O-N 3.39Å; Y106-E108 PolarHBondContact OH-OE2 3.46Å; Y106-G109 WeakPolarHBondContact CD1-O 3.38Å; Y106-G109 VanDerWaalsContact CE1-O 3.22Å; Y106-G109 WeakPolarHBondContact CE1-O 3.2Å; Y106-G109 PolarHBondContact O-N 3.35Å; Y106-L111 HydrophobicContact CE1-CB 4.26Å
107D84.3Confident91.3Very high96 Ų9623.6 Ų23.651%0.51312%0.115SC..THydrogen-bonded Turntrans-50.8-40.3-173.660.53.6000115.3K60 G109K60-D107 WeakPolarHBondContact CD-OD2 3.49Å; K60-D107 IonicContact NZ-OD2 2.87Å; K60-D107 PolarHBondContact NZ-OD2 3.3Å; D107-G109 VanDerWaalsContact C-N 3.26Å; D107-G109 PolarHBondContact O-N 3.38Å
108E84.3Confident91.5Very high102 Ų10221.3 Ų21.348%0.47711%0.109SC..THydrogen-bonded Turntrans-82.35.8178-55.3-170136.300114.5K17 Y106K17-E108 VanDerWaalsContact NZ-CD 3.31Å; K17-E108 IonicContact NZ-OE1 3.94Å; K17-E108 PolarHBondContact NZ-OE1 3.06Å; K17-E108 IonicContact NZ-OE2 2.64Å; K17-E108 PolarHBondContact NZ-OE2 3.17Å; Y106-E108 VanDerWaalsContact C-N 3.34Å; Y106-E108 HydrophobicContact CD2-CB 4.47Å; Y106-E108 HydrophobicContact CE2-CB 3.62Å; Y106-E108 HydrophobicContact CE2-CG 3.72Å; Y106-E108 PolarHBondContact O-N 3.39Å; Y106-E108 PolarHBondContact OH-OE2 3.46Å
109G86.9Confident91.4Very high7 Ų727.3 Ų27.37%0.07214%0.137CC..EExtended strand (participates in β ladder)trans97.6-175.6-178.200000114.1Y106 D107 L111Y106-G109 WeakPolarHBondContact CD1-O 3.38Å; Y106-G109 VanDerWaalsContact CE1-O 3.22Å; Y106-G109 WeakPolarHBondContact CE1-O 3.2Å; Y106-G109 PolarHBondContact O-N 3.35Å; D107-G109 VanDerWaalsContact C-N 3.26Å; D107-G109 PolarHBondContact O-N 3.38Å; G109-L111 PolarHBondContact O-N 3.43Å
110P91.8Very high91.4Very high8 Ų828.3 Ų28.35%0.05214%0.142CC..EExtended strand (participates in β ladder)trans-71.3129.1-172.127.7-34.4000112.3V105 Y112 Y152V105-P110 HydrophobicContact CG2-CB 4.44Å; P110-Y112 HydrophobicContact CB-CE1 4.15Å; P110-Y112 HydrophobicContact CB-CE2 4.18Å; P110-Y112 HydrophobicContact CG-CE2 3.95Å; P110-Y112 WeakPolarHBondContact CG-OH 3.41Å; P110-Y152 HydrophobicContact CG-CE1 4.46Å
111L94.4Very high91.4Very high0 Ų027.2 Ų27.20%014%0.137CC..EExtended strand (participates in β ladder)trans-90.5115.3163.3175.165.7000109.2K12 Q15 F30 Y39 I56 Q103 V104 Y106 G109 V113K12-L111 HydrophobicContact CD-CD1 4.21Å; K12-L111 VanDerWaalsContact CE-CD1 3.45Å; K12-L111 HydrophobicContact CG-CD1 3.93Å; Q15-L111 HydrophobicContact CG-CD1 3.95Å; F30-L111 HydrophobicContact CE1-CD2 4.13Å; Y39-L111 HydrophobicContact CE1-CD2 4.46Å; I56-L111 HydrophobicContact CD1-CB 4.24Å; I56-L111 HydrophobicContact CD1-CD2 3.58Å; Q103-L111 CarbonylContact C-O 3.52Å; Q103-L111 WeakPolarHBondContact CA-O 3.36Å; V104-L111 HydrophobicContact CB-CB 4.37Å; V104-L111 PolarHBondContact N-O 3.39Å; V104-L111 PolarHBondContact O-N 3.08Å; Y106-L111 HydrophobicContact CE1-CB 4.26Å; G109-L111 PolarHBondContact O-N 3.43Å; L111-V113 HydrophobicContact CD2-CG2 4.12Å; L111-V113 HydrophobicContact CG-CG2 3.94Å
112Y95.5Very high91.1Very high9 Ų932.7 Ų32.74%0.03516%0.161CC..EExtended strand (participates in β ladder)trans-90.7129.3174.6-57.6-69.8000111.7R13 V67 Q103 P110 F146 W147R13-Y112 PolarHBondContact N-O 3.46Å; R13-Y112 VanDerWaalsContact N-O 3.08Å; V67-Y112 HydrophobicContact CG1-CE1 4.47Å; V67-Y112 HydrophobicContact CG2-CD1 3.99Å; V67-Y112 HydrophobicContact CG2-CE1 4.07Å; Q103-Y112 HydrophobicContact CB-CD1 3.96Å; Q103-Y112 HydrophobicContact CB-CE1 4.03Å; P110-Y112 HydrophobicContact CB-CE1 4.15Å; P110-Y112 HydrophobicContact CB-CE2 4.18Å; P110-Y112 HydrophobicContact CG-CE2 3.95Å; P110-Y112 WeakPolarHBondContact CG-OH 3.41Å; Y112-F146 AromaticContact CD1-CD1 3.52Å; Y112-F146 HydrophobicContact CD1-CD1 3.52Å; Y112-F146 AromaticContact CD1-CE1 3.59Å; Y112-F146 HydrophobicContact CD1-CE1 3.59Å; Y112-F146 HydrophobicContact CD2-CD1 4.06Å; Y112-F146 HydrophobicContact CD2-CE1 4.48Å; Y112-F146 AromaticContact CE1-CD1 3.62Å; Y112-F146 HydrophobicContact CE1-CD1 3.62Å; Y112-F146 HydrophobicContact CE1-CE1 4.14Å; Y112-F146 HydrophobicContact CE2-CD1 4.17Å; Y112-F146 AromaticContact CG-CD1 3.74Å; Y112-F146 HydrophobicContact CG-CD1 3.74Å; Y112-F146 AromaticContact CG-CE1 3.78Å; Y112-F146 HydrophobicContact CG-CE1 3.78Å; Y112-F146 AromaticContact CZ-CD1 3.96Å; Y112-W147 HydrophobicContact CE2-CB 4.22Å; Y112-W147 WeakPolarHBondContact OH-CB 3.35Å; Y112-W147 PolarHBondContact OH-N 3.17Å
113V95.8Very high90.8Very high1 Ų136.9 Ų36.91%0.00618%0.177CC..EExtended strand (participates in β ladder)trans-131.1139.5-177.5-173.40000108.5F10 F30 P101 F102 L111F10-V113 HydrophobicContact CB-CG1 3.33Å; F10-V113 HydrophobicContact CD1-CG1 4.33Å; F10-V113 HydrophobicContact CD2-CG1 3.56Å; F10-V113 HydrophobicContact CE2-CG1 4.41Å; F10-V113 HydrophobicContact CG-CG1 3.51Å; F30-V113 HydrophobicContact CE1-CG2 4.1Å; F30-V113 HydrophobicContact CE2-CG1 4.16Å; F30-V113 HydrophobicContact CZ-CG1 4.16Å; F30-V113 HydrophobicContact CZ-CG2 3.92Å; P101-V113 CarbonylContact C-O 3.55Å; P101-V113 WeakPolarHBondContact CA-O 3.3Å; F102-V113 HydrophobicContact CD1-CB 4.16Å; F102-V113 HydrophobicContact CD1-CG1 4.45Å; F102-V113 WeakPolarHBondContact CD1-O 3.47Å; F102-V113 HydrophobicContact CE1-CB 3.65Å; F102-V113 HydrophobicContact CE1-CG1 3.54Å; F102-V113 HydrophobicContact CE2-CB 4.02Å; F102-V113 HydrophobicContact CE2-CG1 4.41Å; F102-V113 HydrophobicContact CE2-CG2 4.42Å; F102-V113 HydrophobicContact CZ-CB 3.57Å; F102-V113 HydrophobicContact CZ-CG1 3.52Å; F102-V113 HydrophobicContact CZ-CG2 4.28Å; F102-V113 PolarHBondContact N-O 2.69Å; F102-V113 PolarHBondContact O-N 2.61Å; F102-V113 VanDerWaalsContact O-O 3.09Å; L111-V113 HydrophobicContact CD2-CG2 4.12Å; L111-V113 HydrophobicContact CG-CG2 3.94Å
114F94.8Very high90.7Very high4 Ų436.9 Ų36.92%0.01818%0.177CC..EExtended strand (participates in β ladder)trans-117.8127.8-178.3-63.9-112.7000110F10 L11 R13 F25 R77 F98 P101 F146F10-F114 WeakPolarHBondContact CB-O 3.42Å; F10-F114 WeakPolarHBondContact CD1-O 3.44Å; L11-F114 HydrophobicContact CB-CB 4.15Å; L11-F114 PolarHBondContact N-O 3.47Å; L11-F114 PolarHBondContact O-N 2.76Å; R13-F114 HydrophobicContact CB-CE2 4.23Å; F25-F114 HydrophobicContact CD1-CE2 4.21Å; F25-F114 HydrophobicContact CE1-CD2 4.42Å; F25-F114 AromaticContact CE1-CE2 3.67Å; F25-F114 HydrophobicContact CE1-CE2 3.67Å; F25-F114 AromaticContact CE1-CZ 3.86Å; F25-F114 HydrophobicContact CE1-CZ 3.86Å; R77-F114 HydrophobicContact CG-CD1 4.47Å; F98-F114 HydrophobicContact CB-CB 3.76Å; F98-F114 WeakPolarHBondContact CD1-O 3.49Å; F98-F114 WeakPolarHBondContact O-CB 3.25Å; F98-F114 WeakPolarHBondContact O-CD1 3.14Å; P101-F114 HydrophobicContact CB-CD1 3.71Å; P101-F114 HydrophobicContact CB-CE1 3.67Å; P101-F114 HydrophobicContact CB-CG 4.19Å; P101-F114 HydrophobicContact CB-CZ 4.08Å; P101-F114 HydrophobicContact CG-CD1 4.31Å; P101-F114 HydrophobicContact CG-CE1 4.15Å; F114-F146 AromaticContact CE1-CZ 3.91Å; F114-F146 HydrophobicContact CE1-CZ 3.91Å; F114-F146 HydrophobicContact CE2-CE1 4.31Å; F114-F146 HydrophobicContact CE2-CZ 4.38Å; F114-F146 AromaticContact CZ-CE1 3.8Å; F114-F146 HydrophobicContact CZ-CE1 3.8Å; F114-F146 AromaticContact CZ-CZ 3.48Å; F114-F146 HydrophobicContact CZ-CZ 3.48Å; F114-F146 VanDerWaalsContact CZ-CZ 3.48Å
115S92.9Very high90.5Very high0 Ų037.5 Ų37.50%018%0.18CC..EExtended strand (participates in β ladder)trans-94.8144.5-179.9-178.30000111.4F98 P99 Y100 T117 R121F98-S115 CarbonylContact C-O 3.57Å; F98-S115 WeakPolarHBondContact CA-O 3.32Å; P99-S115 WeakPolarHBondContact CD-O 3.39Å; Y100-S115 PolarHBondContact N-O 3.44Å; Y100-S115 VanDerWaalsContact N-O 3.1Å; Y100-S115 WeakPolarHBondContact O-CB 3.43Å; Y100-S115 PolarHBondContact O-N 2.95Å; S115-T117 WeakPolarHBondContact CB-O 3.44Å; S115-T117 PolarHBondContact OG-N 3.44Å; S115-T117 PolarHBondContact OG-O 2.95Å; S115-R121 PolarHBondContact OG-N 2.95Å
116P86.6Confident90.4Very high14 Ų1441.5 Ų41.59%0.09120%0.197CC..SBendtrans-68.8-35.717428.2-34.8000113I94 R97 F98 Y100 L120I94-P116 HydrophobicContact CG2-CB 4.35Å; I94-P116 HydrophobicContact CG2-CG 4.31Å; I94-P116 WeakPolarHBondContact O-CB 3.44Å; R97-P116 VanDerWaalsContact O-CA 3.26Å; R97-P116 WeakPolarHBondContact O-CA 3.31Å; R97-P116 WeakPolarHBondContact O-CB 3.43Å; F98-P116 HydrophobicContact CD1-CB 4.22Å; F98-P116 HydrophobicContact CD1-CG 4.44Å; F98-P116 HydrophobicContact CE1-CB 4.31Å; F98-P116 HydrophobicContact CE1-CG 4.34Å; Y100-P116 WeakPolarHBondContact CD2-O 3.21Å; Y100-P116 VanDerWaalsContact CE2-O 3.26Å; Y100-P116 WeakPolarHBondContact CE2-O 3.49Å; P116-L120 HydrophobicContact CG-CD2 3.93Å
117T85.9Confident90.2Very high39 Ų3943.3 Ų43.324%0.23921%0.206CC..SBendtrans-123.8156.4179.369.30000112I94 S115 L120 R121I94-T117 HydrophobicContact CG1-CG2 4.22Å; S115-T117 WeakPolarHBondContact CB-O 3.44Å; S115-T117 PolarHBondContact OG-N 3.44Å; S115-T117 PolarHBondContact OG-O 2.95Å; T117-L120 WeakPolarHBondContact OG1-CB 3.48Å; T117-L120 PolarHBondContact OG1-N 3.35Å; T117-R121 PolarHBondContact O-N 3.43Å
118E87.2Confident90.6Very high65 Ų6538.8 Ų38.830%0.30418%0.182SC..Hα-helixtrans-71.5-35.4177.3179167.2-128.800111.1Y100 R121 K122Y100-E118 HydrophobicContact CD1-CB 4.06Å; Y100-E118 HydrophobicContact CE1-CB 3.97Å; Y100-E118 HydrophobicContact CE2-CB 4.41Å; Y100-E118 HydrophobicContact CG-CB 4.34Å; E118-R121 WeakPolarHBondContact O-CB 3.35Å; E118-R121 PolarHBondContact O-N 3.26Å; E118-R121 IonicContact OE1-CZ 2.68Å; E118-R121 IonicContact OE1-NH2 2.74Å; E118-R121 PolarHBondContact OE1-NH2 3.14Å; E118-K122 HydrophobicContact CG-CD 4.05Å; E118-K122 HydrophobicContact CG-CG 4.33Å; E118-K122 WeakPolarHBondContact O-CG 3.39Å; E118-K122 PolarHBondContact O-N 3.36Å; E118-K122 IonicContact OE1-NZ 3.06Å; E118-K122 IonicContact OE2-NZ 3.24Å; E118-K122 PolarHBondContact OE2-NZ 3.33Å
119E87.8Confident91Very high126 Ų12637.6 Ų37.659%0.58918%0.175SC*.Hα-helixtrans-61.6-45.9178.6-66.462.4-134.800110.2K122 R123E119-K122 PolarHBondContact O-N 2.86Å; E119-R123 WeakPolarHBondContact O-CB 3.45Å; E119-R123 PolarHBondContact O-N 2.81Å
120L87.3Confident91Very high26 Ų2640.3 Ų40.314%0.13619%0.188CC..Hα-helixtrans-65.5-40.5177.7-173.162.4000111.2F10 P116 T117 R123 W124F10-L120 HydrophobicContact CE1-CD2 3.75Å; F10-L120 HydrophobicContact CE1-CG 4.05Å; F10-L120 HydrophobicContact CZ-CD2 4.19Å; F10-L120 HydrophobicContact CZ-CG 4.16Å; P116-L120 HydrophobicContact CG-CD2 3.93Å; T117-L120 WeakPolarHBondContact OG1-CB 3.48Å; T117-L120 PolarHBondContact OG1-N 3.35Å; L120-R123 PolarHBondContact O-N 2.93Å; L120-W124 VanDerWaalsContact O-CD1 3.27Å; L120-W124 PolarHBondContact O-N 3.44Å
121R93.9Very high90.9Very high23 Ų2341.4 Ų41.49%0.08719%0.194CC..Hα-helixtrans-59-51.3173.4179.1178.864.5173.5-0.6111.5P101 F102 S115 T117 E118 R123 W124 I125P101-R121 VanDerWaalsContact O-CD 3.32Å; P101-R121 WeakPolarHBondContact O-CD 3.47Å; P101-R121 PolarHBondContact O-NH1 3.01Å; F102-R121 HydrophobicContact CB-CG 4.14Å; F102-R121 HydrophobicContact CD1-CG 4.08Å; F102-R121 HydrophobicContact CG-CG 4.41Å; S115-R121 PolarHBondContact OG-N 2.95Å; T117-R121 PolarHBondContact O-N 3.43Å; E118-R121 WeakPolarHBondContact O-CB 3.35Å; E118-R121 PolarHBondContact O-N 3.26Å; E118-R121 IonicContact OE1-CZ 2.68Å; E118-R121 IonicContact OE1-NH2 2.74Å; E118-R121 PolarHBondContact OE1-NH2 3.14Å; R121-R123 VanDerWaalsContact C-N 3.28Å; R121-R123 PolarHBondContact O-N 2.85Å; R121-W124 PolarHBondContact O-N 2.92Å; R121-I125 HydrophobicContact CG-CD1 3.79Å; R121-I125 HydrophobicContact CG-CG1 4.45Å; R121-I125 WeakPolarHBondContact O-CG1 3.48Å; R121-I125 PolarHBondContact O-N 3.28Å
122K89.6Confident90.7Very high114 Ų11441.7 Ų41.750%0.49620%0.196SC..Hα-helixtrans-57.2-44.4-180-76.9170.5-179.1156.80110.8E118 E119 H126E118-K122 HydrophobicContact CG-CD 4.05Å; E118-K122 HydrophobicContact CG-CG 4.33Å; E118-K122 WeakPolarHBondContact O-CG 3.39Å; E118-K122 PolarHBondContact O-N 3.36Å; E118-K122 IonicContact OE1-NZ 3.06Å; E118-K122 IonicContact OE2-NZ 3.24Å; E118-K122 PolarHBondContact OE2-NZ 3.33Å; E119-K122 PolarHBondContact O-N 2.86Å; K122-H126 WeakPolarHBondContact O-CB 3.35Å; K122-H126 PolarHBondContact O-N 2.84Å
123R89.8Confident90.3Very high91 Ų9148.3 Ų48.334%0.34322%0.22SC..Hα-helixtrans-61.1-47.7177.4-176.8179-179.71683.3112.7E119 L120 R121 H126 Q127 Y369E119-R123 WeakPolarHBondContact O-CB 3.45Å; E119-R123 PolarHBondContact O-N 2.81Å; L120-R123 PolarHBondContact O-N 2.93Å; R121-R123 VanDerWaalsContact C-N 3.28Å; R121-R123 PolarHBondContact O-N 2.85Å; R123-H126 PolarHBondContact O-N 2.85Å; R123-Q127 WeakPolarHBondContact O-CB 3.16Å; R123-Q127 PolarHBondContact O-N 3.43Å; R123-Y369 VanDerWaalsContact NH1-CE2 3.32Å; R123-Y369 VanDerWaalsContact NH1-CZ 3.26Å
124W93.4Very high89.5Confident2 Ų256.9 Ų56.91%0.00825%0.254CS..Hα-helixtrans-64.9-43.6-179.9-89.677.1000112.5L6 S8 F10 F30 L32 L37 F102 L120 R121 Q127 L128L6-W124 HydrophobicContact CB-CD2 4.26Å; L6-W124 HydrophobicContact CB-CH2 3.94Å; L6-W124 HydrophobicContact CB-CZ2 3.56Å; L6-W124 HydrophobicContact CB-CZ3 4.43Å; L6-W124 HydrophobicContact CD1-CB 4.44Å; L6-W124 HydrophobicContact CD1-CD2 3.76Å; L6-W124 HydrophobicContact CD1-CE3 4.25Å; L6-W124 HydrophobicContact CD1-CG 3.84Å; S8-W124 PolarHBondContact OG-NE1 2.79Å; F10-W124 AromaticContact CE2-CD2 3.53Å; F10-W124 HydrophobicContact CE2-CD2 3.53Å; F10-W124 AromaticContact CE2-CE2 3.41Å; F10-W124 VanDerWaalsContact CE2-CE2 3.41Å; F10-W124 AromaticContact CE2-CE3 3.92Å; F10-W124 HydrophobicContact CE2-CE3 3.92Å; F10-W124 AromaticContact CE2-CG 4Å; F10-W124 HydrophobicContact CE2-CG 4Å; F10-W124 HydrophobicContact CE2-CH2 4.09Å; F10-W124 AromaticContact CE2-CZ2 3.71Å; F10-W124 HydrophobicContact CE2-CZ2 3.71Å; F10-W124 HydrophobicContact CE2-CZ3 4.18Å; F10-W124 AromaticContact CE2-NE1 3.78Å; F10-W124 AromaticContact CZ-CD1 3.56Å; F10-W124 AromaticContact CZ-CD2 3.77Å; F10-W124 HydrophobicContact CZ-CD2 3.77Å; F10-W124 AromaticContact CZ-CE2 3.62Å; F10-W124 AromaticContact CZ-CG 3.73Å; F10-W124 HydrophobicContact CZ-CG 3.73Å; F10-W124 HydrophobicContact CZ-CZ2 4.29Å; F10-W124 AromaticContact CZ-NE1 3.46Å; F30-W124 HydrophobicContact CB-CH2 3.68Å; F30-W124 HydrophobicContact CB-CZ2 4.4Å; F30-W124 HydrophobicContact CB-CZ3 4.2Å; L32-W124 HydrophobicContact CB-CH2 4.23Å; L32-W124 HydrophobicContact CB-CZ3 4.02Å; L37-W124 HydrophobicContact CD1-CZ3 3.81Å; F102-W124 HydrophobicContact CZ-CB 4.47Å; L120-W124 VanDerWaalsContact O-CD1 3.27Å; L120-W124 PolarHBondContact O-N 3.44Å; R121-W124 PolarHBondContact O-N 2.92Å; W124-Q127 PolarHBondContact O-N 2.92Å; W124-L128 HydrophobicContact CE3-CD1 4.22Å; W124-L128 VanDerWaalsContact O-CB 3.29Å; W124-L128 WeakPolarHBondContact O-CB 3.4Å; W124-L128 WeakPolarHBondContact O-CG 3.47Å; W124-L128 PolarHBondContact O-N 3.32Å
125I93Very high89.1Confident13 Ų1358 Ų587%0.06726%0.26CS..Hα-helixtrans-61.3-47.3175.8-66.2171.8000110.3V64 T66 F102 R121 Q127 L128 K129V64-I125 HydrophobicContact CG1-CB 4.43Å; V64-I125 HydrophobicContact CG1-CG1 4.16Å; V64-I125 HydrophobicContact CG1-CG2 4.36Å; T66-I125 HydrophobicContact CG2-CD1 3.48Å; T66-I125 VanDerWaalsContact CG2-CD1 3.48Å; F102-I125 HydrophobicContact CB-CD1 3.84Å; F102-I125 HydrophobicContact CB-CG1 4.11Å; F102-I125 HydrophobicContact CD2-CG1 4.32Å; F102-I125 HydrophobicContact CG-CG1 4.33Å; R121-I125 HydrophobicContact CG-CD1 3.79Å; R121-I125 HydrophobicContact CG-CG1 4.45Å; R121-I125 WeakPolarHBondContact O-CG1 3.48Å; R121-I125 PolarHBondContact O-N 3.28Å; I125-Q127 PolarHBondContact O-N 2.78Å; I125-L128 PolarHBondContact O-N 3.22Å; I125-K129 HydrophobicContact CG2-CD 4.08Å; I125-K129 HydrophobicContact CG2-CG 4.38Å; I125-K129 WeakPolarHBondContact O-CB 3.45Å; I125-K129 WeakPolarHBondContact O-CG 3.44Å; I125-K129 PolarHBondContact O-N 2.85Å
126H90.9Very high88.5Confident113 Ų11363.2 Ų63.252%0.52330%0.296SS..Hα-helixtrans-58.4-48.1178.9-178.976.7000111.7K122 R123 K129 N130K122-H126 WeakPolarHBondContact O-CB 3.35Å; K122-H126 PolarHBondContact O-N 2.84Å; R123-H126 PolarHBondContact O-N 2.85Å; H126-K129 PolarHBondContact O-N 2.83Å; H126-N130 PolarHBondContact CD2-ND2 3.04Å; H126-N130 PolarHBondContact NE2-ND2 2.76Å; H126-N130 VanDerWaalsContact O-CG 3.29Å; H126-N130 PolarHBondContact O-N 3.07Å
127Q89.1Confident88.5Confident57 Ų5767.8 Ų67.827%0.26632%0.32SS..Hα-helixtrans-68-42.2-178.7-167.362.421.500112.1I5 L6 L32 R123 W124 I125 K129 N130 V131I5-Q127 HydrophobicContact CG2-CG 3.57Å; I5-Q127 VanDerWaalsContact CG2-NE2 3.28Å; L6-Q127 HydrophobicContact CD1-CB 3.55Å; L6-Q127 HydrophobicContact CD1-CG 3.84Å; L6-Q127 HydrophobicContact CG-CB 4.38Å; L6-Q127 HydrophobicContact CG-CG 4.16Å; L32-Q127 HydrophobicContact CD2-CG 4.12Å; R123-Q127 WeakPolarHBondContact O-CB 3.16Å; R123-Q127 PolarHBondContact O-N 3.43Å; W124-Q127 PolarHBondContact O-N 2.92Å; I125-Q127 PolarHBondContact O-N 2.78Å; Q127-K129 PolarHBondContact O-N 3.26Å; Q127-N130 PolarHBondContact O-N 3.33Å; Q127-V131 VanDerWaalsContact O-CG2 3.29Å; Q127-V131 WeakPolarHBondContact O-CG2 3.08Å; Q127-V131 PolarHBondContact O-N 2.81Å
128L92.6Very high88.6Confident1 Ų169.4 Ų69.41%0.00533%0.327CS..Hα-helixtrans-60.8-45.3175.7-79.3164.8000111.1L32 I61 V64 F102 V104 W124 I125 N130 V131 I132L32-L128 HydrophobicContact CD1-CD2 3.6Å; L32-L128 HydrophobicContact CD2-CD2 3.79Å; L32-L128 HydrophobicContact CD2-CG 4.02Å; L32-L128 HydrophobicContact CG-CD2 4.33Å; I61-L128 HydrophobicContact CD1-CD2 4.43Å; V64-L128 HydrophobicContact CB-CB 4.17Å; V64-L128 HydrophobicContact CG1-CB 3.97Å; V64-L128 HydrophobicContact CG1-CD1 3.77Å; V64-L128 HydrophobicContact CG2-CB 3.92Å; V64-L128 HydrophobicContact CG2-CD1 4.24Å; F102-L128 HydrophobicContact CE2-CD1 4.29Å; V104-L128 HydrophobicContact CG2-CD1 4.17Å; W124-L128 HydrophobicContact CE3-CD1 4.22Å; W124-L128 VanDerWaalsContact O-CB 3.29Å; W124-L128 WeakPolarHBondContact O-CB 3.4Å; W124-L128 WeakPolarHBondContact O-CG 3.47Å; W124-L128 PolarHBondContact O-N 3.32Å; I125-L128 PolarHBondContact O-N 3.22Å; L128-N130 VanDerWaalsContact C-N 3.31Å; L128-N130 PolarHBondContact O-N 3.45Å; L128-V131 PolarHBondContact O-N 2.78Å; L128-I132 WeakPolarHBondContact O-CG1 3.42Å; L128-I132 WeakPolarHBondContact O-CG2 3.37Å; L128-I132 PolarHBondContact O-N 3.44Å
129K91.1Very high88.6Confident77 Ų7769.1 Ų69.134%0.33533%0.33SS..Hα-helixtrans-57.4-42174.1-76.9-175.6177-173.50112.3V64 E65 I125 H126 Q127 R133V64-K129 WeakPolarHBondContact O-CE 3.25Å; E65-K129 WeakPolarHBondContact OE2-CE 3.5Å; E65-K129 IonicContact OE2-NZ 2.69Å; E65-K129 PolarHBondContact OE2-NZ 3.22Å; I125-K129 HydrophobicContact CG2-CD 4.08Å; I125-K129 HydrophobicContact CG2-CG 4.38Å; I125-K129 WeakPolarHBondContact O-CB 3.45Å; I125-K129 WeakPolarHBondContact O-CG 3.44Å; I125-K129 PolarHBondContact O-N 2.85Å; H126-K129 PolarHBondContact O-N 2.83Å; Q127-K129 PolarHBondContact O-N 3.26Å; K129-R133 PolarHBondContact O-N 3.24Å
130N88.4Confident88.5Confident64 Ų6470.9 Ų70.934%0.34234%0.338SS..Hα-helixtrans-64.7-39.1177.1-73.2-13.5000112.6H126 Q127 L128 R133H126-N130 PolarHBondContact CD2-ND2 3.04Å; H126-N130 PolarHBondContact NE2-ND2 2.76Å; H126-N130 VanDerWaalsContact O-CG 3.29Å; H126-N130 PolarHBondContact O-N 3.07Å; Q127-N130 PolarHBondContact O-N 3.33Å; L128-N130 VanDerWaalsContact C-N 3.31Å; L128-N130 PolarHBondContact O-N 3.45Å; N130-R133 VanDerWaalsContact O-CD 3.29Å; N130-R133 WeakPolarHBondContact O-CD 3.42Å; N130-R133 VanDerWaalsContact O-CG 3.23Å; N130-R133 WeakPolarHBondContact O-CG 3.39Å
131V89Confident88.6Confident30 Ų3073.9 Ų73.918%0.18235%0.35CS..Hα-helixtrans-73.7-39.3-178.7-179.90000111.1I5 V58 Q127 L128 R133I5-V131 HydrophobicContact CD1-CG2 3.83Å; V58-V131 HydrophobicContact CG1-CB 4.49Å; V58-V131 HydrophobicContact CG1-CG1 3.47Å; V58-V131 VanDerWaalsContact CG1-CG1 3.47Å; Q127-V131 VanDerWaalsContact O-CG2 3.29Å; Q127-V131 WeakPolarHBondContact O-CG2 3.08Å; Q127-V131 PolarHBondContact O-N 2.81Å; L128-V131 PolarHBondContact O-N 2.78Å; V131-R133 VanDerWaalsContact C-N 3.27Å; V131-R133 PolarHBondContact O-N 2.8Å
132I90.2Very high88.5Confident7 Ų773.9 Ų73.94%0.03635%0.35CS..Hα-helixtrans-81.2-2.6-178.471.4-179.7000113.7V58 I61 V64 L128 Y134 N135 L138V58-I132 HydrophobicContact CG1-CG2 4.09Å; I61-I132 HydrophobicContact CB-CG2 3.8Å; I61-I132 HydrophobicContact CD1-CG2 4.36Å; I61-I132 HydrophobicContact CG2-CD1 4.06Å; I61-I132 HydrophobicContact CG2-CG2 3.88Å; V64-I132 HydrophobicContact CG2-CD1 4.24Å; L128-I132 WeakPolarHBondContact O-CG1 3.42Å; L128-I132 WeakPolarHBondContact O-CG2 3.37Å; L128-I132 PolarHBondContact O-N 3.44Å; I132-Y134 PolarHBondContact O-N 2.96Å; I132-N135 WeakPolarHBondContact CB-ND2 3.41Å; I132-N135 WeakPolarHBondContact O-CB 3.29Å; I132-N135 PolarHBondContact O-N 3.32Å; I132-L138 HydrophobicContact CB-CD2 4.21Å; I132-L138 HydrophobicContact CD1-CD2 3.87Å; I132-L138 HydrophobicContact CG1-CD2 3.9Å; I132-L138 WeakPolarHBondContact O-CD1 3.45Å
133R86.7Confident88.7Confident147 Ų14768.9 Ų68.956%0.55533%0.328SS*.THydrogen-bonded Turntrans-57.1-19.1-17277.1-175.3-175-177.51.6115K129 N130 V131K129-R133 PolarHBondContact O-N 3.24Å; N130-R133 VanDerWaalsContact O-CD 3.29Å; N130-R133 WeakPolarHBondContact O-CD 3.42Å; N130-R133 VanDerWaalsContact O-CG 3.23Å; N130-R133 WeakPolarHBondContact O-CG 3.39Å; V131-R133 VanDerWaalsContact C-N 3.27Å; V131-R133 PolarHBondContact O-N 2.8Å
134Y78.8Confident88.8Confident181 Ų18165.3 Ų65.371%0.7132%0.317SS*.THydrogen-bonded Turntrans-107.76.7-179.9-61.9-61000113.7I132I132-Y134 PolarHBondContact O-N 2.96Å
135N88.1Confident88.7Confident29 Ų2966.5 Ų66.516%0.15533%0.325CS..  trans-69.8142.7175.2-67.22000109.9V58 E59 I61 I132 L138V58-N135 PolarHBondContact O-ND2 2.98Å; E59-N135 PolarHBondContact O-ND2 3.46Å; I61-N135 PolarHBondContact O-ND2 2.9Å; I132-N135 WeakPolarHBondContact CB-ND2 3.41Å; I132-N135 WeakPolarHBondContact O-CB 3.29Å; I132-N135 PolarHBondContact O-N 3.32Å; N135-L138 HydrophobicContact CB-CD2 4.13Å; N135-L138 HydrophobicContact CB-CG 4.18Å
136S80.1Confident88.6Confident108 Ų10866 Ų6676%0.75532%0.323SS*.THydrogen-bonded Turntrans-70.1-30.5-179.346.70000113.6
137D85.4Confident88.5Confident110 Ų11061.7 Ų61.759%0.58830%0.302SS*.THydrogen-bonded Turntrans-105.532.8-167.7-58.6-41.3000113.6T62 V139T62-D137 VanDerWaalsContact CB-O 3.26Å; T62-D137 WeakPolarHBondContact CB-O 3.35Å; T62-D137 HydrophobicContact CG2-CB 4.18Å; T62-D137 WeakPolarHBondContact CG2-O 3.46Å; D137-V139 PolarHBondContact O-N 3.3Å
138L88.1Confident88.4Confident73 Ų7360.7 Ų60.738%0.38230%0.298SS..  trans-66.7124.4178-67.5178.2000111.3I132 N135I132-L138 HydrophobicContact CB-CD2 4.21Å; I132-L138 HydrophobicContact CD1-CD2 3.87Å; I132-L138 HydrophobicContact CG1-CD2 3.9Å; I132-L138 WeakPolarHBondContact O-CD1 3.45Å; N135-L138 HydrophobicContact CB-CD2 4.13Å; N135-L138 HydrophobicContact CB-CG 4.18Å
139V87.3Confident88Confident60 Ų6067 Ų6736%0.36433%0.331SS..  trans-84.5142.8177.8-650000110.7T62 C63 D137 K141 L168T62-V139 PolarHBondContact O-N 3.03Å; T62-V139 VanDerWaalsContact O-N 3.15Å; C63-V139 HydrophobicContact CB-CG2 3.52Å; D137-V139 PolarHBondContact O-N 3.3Å; V139-K141 WeakPolarHBondContact CG2-O 3.28Å; V139-L168 WeakPolarHBondContact O-CD1 3.32Å
140Q86.2Confident87.7Confident162 Ų16264.2 Ų64.276%0.75733%0.325SS*.SBendtrans-86-11.9176.6-64.7-178.6-7.100113.4L168Q140-L168 PolarHBondContact O-N 2.81Å
141K88.9Confident87.7Confident89 Ų8965 Ų6539%0.38733%0.326SS..EExtended strand (participates in β ladder)trans-130.6146-178-59.9-177-177.8176.90111.1V139 M163 G164 Q166 I167V139-K141 WeakPolarHBondContact CG2-O 3.28Å; K141-M163 HydrophobicContact CD-CG 4.49Å; K141-M163 HydrophobicContact CD-SD 4.39Å; K141-G164 VanDerWaalsContact CB-O 3.31Å; K141-G164 WeakPolarHBondContact CB-O 3.34Å; K141-G164 WeakPolarHBondContact CD-O 3.39Å; K141-Q166 CarbonylContact C-O 3.54Å; K141-Q166 WeakPolarHBondContact CA-O 3.47Å; K141-Q166 WeakPolarHBondContact CB-O 3.48Å; K141-I167 HydrophobicContact CG-CG1 4.19Å
142Y92.5Very high87.8Confident24 Ų2463.7 Ų63.79%0.09432%0.318CS..EExtended strand (participates in β ladder)trans-136.5171.7179.678.2-72.1000111.8E65 P144 G164 C165 Q166 L168E65-Y142 HydrophobicContact CB-CD2 3.79Å; E65-Y142 HydrophobicContact CB-CE2 3.81Å; E65-Y142 HydrophobicContact CB-CG 4.35Å; E65-Y142 HydrophobicContact CG-CD2 3.79Å; E65-Y142 HydrophobicContact CG-CE1 4.1Å; E65-Y142 HydrophobicContact CG-CE2 3.29Å; E65-Y142 HydrophobicContact CG-CG 4.36Å; E65-Y142 VanDerWaalsContact CG-CZ 3.47Å; Y142-P144 HydrophobicContact CE2-CB 4.1Å; Y142-G164 VanDerWaalsContact C-CA 3.44Å; Y142-G164 CarbonylContact O-C 3.42Å; Y142-G164 WeakPolarHBondContact O-CA 3.38Å; Y142-C165 PolarHBondContact O-N 3.41Å; Y142-Q166 HydrophobicContact CD1-CB 4.36Å; Y142-Q166 WeakPolarHBondContact CD1-O 3.5Å; Y142-Q166 HydrophobicContact CE1-CB 4.03Å; Y142-Q166 HydrophobicContact CE1-CG 3.89Å; Y142-Q166 PolarHBondContact N-O 2.73Å; Y142-Q166 PolarHBondContact O-N 3.17Å; Y142-Q166 PolarHBondContact OH-NE2 2.76Å; Y142-L168 HydrophobicContact CD1-CD2 3.56Å; Y142-L168 HydrophobicContact CD1-CG 3.91Å; Y142-L168 HydrophobicContact CE1-CD2 3.94Å; Y142-L168 HydrophobicContact CG-CD2 4.15Å
143H92.4Very high87.9Confident8 Ų868 Ų684%0.03734%0.341CS..  trans-102.5115.2175.8-70.3-66.8000109.7Q103 C145 Y152 C155 A162 M163Q103-H143 PolarHBondContact NE2-O 3Å; Q103-H143 PolarHBondContact OE1-O 2.98Å; H143-C145 VanDerWaalsContact C-N 3.28Å; H143-C145 PolarHBondContact O-N 3.26Å; H143-Y152 HydrophobicContact CB-CD1 3.57Å; H143-Y152 HydrophobicContact CB-CE1 3.63Å; H143-Y152 HydrophobicContact CB-CG 4.2Å; H143-Y152 AromaticContact CD2-CD1 3.89Å; H143-Y152 AromaticContact CD2-CD2 3.75Å; H143-Y152 AromaticContact CD2-CE1 3.55Å; H143-Y152 AromaticContact CD2-CE2 3.4Å; H143-Y152 WeakPolarHBondContact CD2-CE2 3.47Å; H143-Y152 AromaticContact CD2-CG 3.99Å; H143-Y152 AromaticContact CD2-CZ 3.3Å; H143-Y152 AromaticContact CE1-CD2 3.75Å; H143-Y152 AromaticContact CG-CD1 3.57Å; H143-Y152 AromaticContact CG-CD2 3.95Å; H143-Y152 AromaticContact CG-CE1 3.64Å; H143-Y152 AromaticContact CG-CG 3.74Å; H143-Y152 AromaticContact CG-CZ 3.87Å; H143-Y152 AromaticContact ND1-CD2 3.99Å; H143-Y152 AromaticContact ND1-CG 3.83Å; H143-Y152 AromaticContact NE2-CD2 3.61Å; H143-Y152 AromaticContact NE2-CE2 3.43Å; H143-Y152 WeakPolarHBondContact NE2-CE2 3.29Å; H143-Y152 AromaticContact NE2-CZ 3.86Å; H143-C155 VanDerWaalsContact CE1-SG 3.56Å; H143-A162 PolarHBondContact NE2-O 2.84Å; H143-M163 PolarHBondContact CE1-O 2.85Å; H143-M163 PolarHBondContact NE2-O 3.31Å
144P91.9Very high88Confident17 Ų1763 Ų6311%0.1133%0.328CS..SBendtrans-73-18.4-176.629.4-37000113.6V67 V68 Y142 C154 Q166V67-P144 CarbonylContact C-O 3.56Å; V67-P144 WeakPolarHBondContact CA-O 3.14Å; V68-P144 HydrophobicContact CG2-CB 4.34Å; V68-P144 WeakPolarHBondContact CG2-O 2.89Å; V68-P144 PolarHBondContact N-O 3.37Å; Y142-P144 HydrophobicContact CE2-CB 4.1Å; P144-C154 HydrophobicContact CG-CB 3.8Å; P144-Q166 HydrophobicContact CG-CB 4.4Å
145C92.4Very high88.6Confident26 Ų2656.4 Ų56.418%0.17631%0.308CS..SBendtrans-113.4162.2-176.9-59.60000112.4H143 L153 C154H143-C145 VanDerWaalsContact C-N 3.28Å; H143-C145 PolarHBondContact O-N 3.26Å; C145-L153 HydrophobicContact CB-CB 3.85Å; C145-C154 HydrophobicContact CB-CB 3.71Å
146F91.4Very high88.7Confident4 Ų458.8 Ų58.82%0.01833%0.327CS..  trans-60.9147.3178.7-70-69.1000113.9V67 V68 E70 P101 Y112 F114 I148 L153V67-F146 HydrophobicContact CB-CE1 4.4Å; V67-F146 HydrophobicContact CB-CZ 4.35Å; V67-F146 HydrophobicContact CG1-CD1 3.79Å; V67-F146 HydrophobicContact CG1-CD2 3.91Å; V67-F146 HydrophobicContact CG1-CE1 3.7Å; V67-F146 HydrophobicContact CG1-CE2 3.79Å; V67-F146 HydrophobicContact CG1-CG 3.91Å; V67-F146 HydrophobicContact CG1-CZ 3.7Å; V68-F146 WeakPolarHBondContact O-CE2 3.42Å; E70-F146 HydrophobicContact CG-CD2 3.99Å; E70-F146 HydrophobicContact CG-CE2 3.62Å; E70-F146 HydrophobicContact CG-CZ 4.45Å; P101-F146 HydrophobicContact CB-CE1 4.31Å; P101-F146 HydrophobicContact CB-CZ 3.68Å; P101-F146 HydrophobicContact CG-CE2 4.44Å; P101-F146 HydrophobicContact CG-CZ 3.91Å; Y112-F146 AromaticContact CD1-CD1 3.52Å; Y112-F146 HydrophobicContact CD1-CD1 3.52Å; Y112-F146 AromaticContact CD1-CE1 3.59Å; Y112-F146 HydrophobicContact CD1-CE1 3.59Å; Y112-F146 HydrophobicContact CD2-CD1 4.06Å; Y112-F146 HydrophobicContact CD2-CE1 4.48Å; Y112-F146 AromaticContact CE1-CD1 3.62Å; Y112-F146 HydrophobicContact CE1-CD1 3.62Å; Y112-F146 HydrophobicContact CE1-CE1 4.14Å; Y112-F146 HydrophobicContact CE2-CD1 4.17Å; Y112-F146 AromaticContact CG-CD1 3.74Å; Y112-F146 HydrophobicContact CG-CD1 3.74Å; Y112-F146 AromaticContact CG-CE1 3.78Å; Y112-F146 HydrophobicContact CG-CE1 3.78Å; Y112-F146 AromaticContact CZ-CD1 3.96Å; F114-F146 AromaticContact CE1-CZ 3.91Å; F114-F146 HydrophobicContact CE1-CZ 3.91Å; F114-F146 HydrophobicContact CE2-CE1 4.31Å; F114-F146 HydrophobicContact CE2-CZ 4.38Å; F114-F146 AromaticContact CZ-CE1 3.8Å; F114-F146 HydrophobicContact CZ-CE1 3.8Å; F114-F146 AromaticContact CZ-CZ 3.48Å; F114-F146 HydrophobicContact CZ-CZ 3.48Å; F114-F146 VanDerWaalsContact CZ-CZ 3.48Å; F146-I148 HydrophobicContact CB-CD1 3.92Å; F146-I148 HydrophobicContact CB-CG1 3.75Å; F146-L153 HydrophobicContact CB-CD1 4.5Å; F146-L153 WeakPolarHBondContact O-CG 3.49Å; F146-L153 PolarHBondContact O-N 2.87Å
147W89Confident89.1Confident22 Ų2256.6 Ų56.68%0.08331%0.305CS..EExtended strand (participates in β ladder)trans-79.6118158.2177.7-84.3000109.8R13 Y112 G150 Q151 Y152 Q157 T158 A159 K160R13-W147 PolarHBondContact NH1-O 2.81Å; R13-W147 PolarHBondContact NH2-O 2.78Å; Y112-W147 HydrophobicContact CE2-CB 4.22Å; Y112-W147 WeakPolarHBondContact OH-CB 3.35Å; Y112-W147 PolarHBondContact OH-N 3.17Å; W147-G150 VanDerWaalsContact CH2-O 3.26Å; W147-G150 WeakPolarHBondContact CH2-O 3.47Å; W147-G150 VanDerWaalsContact CZ2-CA 3.45Å; W147-G150 WeakPolarHBondContact CZ2-O 3.48Å; W147-Q151 WeakPolarHBondContact CA-O 3.33Å; W147-Q151 VanDerWaalsContact CE3-C 3.49Å; W147-Y152 HydrophobicContact CB-CD1 4.12Å; W147-Y152 HydrophobicContact CB-CE1 3.96Å; W147-Y152 HydrophobicContact CE3-CD1 4.07Å; W147-Y152 AromaticContact CE3-CD2 3.39Å; W147-Y152 HydrophobicContact CE3-CD2 3.39Å; W147-Y152 HydrophobicContact CE3-CE1 4.1Å; W147-Y152 AromaticContact CE3-CE2 3.43Å; W147-Y152 HydrophobicContact CE3-CE2 3.43Å; W147-Y152 VanDerWaalsContact CE3-CE2 3.43Å; W147-Y152 AromaticContact CE3-CG 3.71Å; W147-Y152 HydrophobicContact CE3-CG 3.71Å; W147-Y152 AromaticContact CE3-CZ 3.79Å; W147-Y152 AromaticContact CZ3-CD2 3.59Å; W147-Y152 HydrophobicContact CZ3-CD2 3.59Å; W147-Y152 AromaticContact CZ3-CE2 3.67Å; W147-Y152 HydrophobicContact CZ3-CE2 3.67Å; W147-Y152 HydrophobicContact CZ3-CG 4.3Å; W147-Q157 WeakPolarHBondContact CZ3-O 3.33Å; W147-T158 WeakPolarHBondContact CH2-O 3.5Å; W147-A159 WeakPolarHBondContact CZ3-O 3.34Å; W147-K160 HydrophobicContact CD2-CG 3.72Å; W147-K160 VanDerWaalsContact CE2-CG 3.41Å; W147-K160 HydrophobicContact CE3-CG 4.09Å; W147-K160 HydrophobicContact CG-CG 4.28Å; W147-K160 HydrophobicContact CH2-CB 4.43Å; W147-K160 HydrophobicContact CH2-CG 3.79Å; W147-K160 HydrophobicContact CZ2-CD 4.45Å; W147-K160 HydrophobicContact CZ2-CG 3.45Å; W147-K160 VanDerWaalsContact CZ2-CG 3.45Å; W147-K160 HydrophobicContact CZ3-CG 4.14Å; W147-K160 VanDerWaalsContact NE1-CE 3.31Å
148I86.1Confident89.4Confident36 Ų3656.6 Ų56.619%0.18531%0.309CS..EExtended strand (participates in β ladder)trans-141.1140.6179.7-50.3-167000108.5F146 G150 Q151 L153F146-I148 HydrophobicContact CB-CD1 3.92Å; F146-I148 HydrophobicContact CB-CG1 3.75Å; I148-G150 PolarHBondContact O-N 3.2Å; I148-Q151 PolarHBondContact N-O 3.44Å; I148-Q151 PolarHBondContact O-N 3.27Å; I148-L153 HydrophobicContact CD1-CD1 3.88Å; I148-L153 HydrophobicContact CG1-CD1 4.19Å; I148-L153 HydrophobicContact CG1-CG 4.48Å
149D83.9Confident89.3Confident132 Ų13255.1 Ų55.171%0.70631%0.307SS*.THydrogen-bonded Turntrans53.827.3174.9-57.6-29.2000116.2
150G84.9Confident89.1Confident20 Ų2055.1 Ų55.121%0.20630%0.302CS..THydrogen-bonded Turntrans89.813.5177.500000114.6W147 I148 T158W147-G150 VanDerWaalsContact CH2-O 3.26Å; W147-G150 WeakPolarHBondContact CH2-O 3.47Å; W147-G150 VanDerWaalsContact CZ2-CA 3.45Å; W147-G150 WeakPolarHBondContact CZ2-O 3.48Å; I148-G150 PolarHBondContact O-N 3.2Å; G150-T158 VanDerWaalsContact O-CA 3.31Å; G150-T158 WeakPolarHBondContact O-CA 3.39Å
151Q89.4Confident89.1Confident79 Ų7954.2 Ų54.237%0.36930%0.303SS..EExtended strand (participates in β ladder)trans-145156.7174.565-177.219.100113.3W147 I148 Q157 T158W147-Q151 WeakPolarHBondContact CA-O 3.33Å; W147-Q151 VanDerWaalsContact CE3-C 3.49Å; I148-Q151 PolarHBondContact N-O 3.44Å; I148-Q151 PolarHBondContact O-N 3.27Å; Q151-Q157 CarbonylContact C-O 3.52Å; Q151-Q157 VanDerWaalsContact CA-O 3.24Å; Q151-Q157 WeakPolarHBondContact CA-O 3.34Å; Q151-T158 HydrophobicContact CB-CG2 4.27Å
152Y90.9Very high88.9Confident4 Ų451.1 Ų51.12%0.01629%0.293CS..EExtended strand (participates in β ladder)trans-79126.3167.5-77.7-72.3000111P110 H143 W147 C154 C155 S156 Q157 A159 K160P110-Y152 HydrophobicContact CG-CE1 4.46Å; H143-Y152 HydrophobicContact CB-CD1 3.57Å; H143-Y152 HydrophobicContact CB-CE1 3.63Å; H143-Y152 HydrophobicContact CB-CG 4.2Å; H143-Y152 AromaticContact CD2-CD1 3.89Å; H143-Y152 AromaticContact CD2-CD2 3.75Å; H143-Y152 AromaticContact CD2-CE1 3.55Å; H143-Y152 AromaticContact CD2-CE2 3.4Å; H143-Y152 WeakPolarHBondContact CD2-CE2 3.47Å; H143-Y152 AromaticContact CD2-CG 3.99Å; H143-Y152 AromaticContact CD2-CZ 3.3Å; H143-Y152 AromaticContact CE1-CD2 3.75Å; H143-Y152 AromaticContact CG-CD1 3.57Å; H143-Y152 AromaticContact CG-CD2 3.95Å; H143-Y152 AromaticContact CG-CE1 3.64Å; H143-Y152 AromaticContact CG-CG 3.74Å; H143-Y152 AromaticContact CG-CZ 3.87Å; H143-Y152 AromaticContact ND1-CD2 3.99Å; H143-Y152 AromaticContact ND1-CG 3.83Å; H143-Y152 AromaticContact NE2-CD2 3.61Å; H143-Y152 AromaticContact NE2-CE2 3.43Å; H143-Y152 WeakPolarHBondContact NE2-CE2 3.29Å; H143-Y152 AromaticContact NE2-CZ 3.86Å; W147-Y152 HydrophobicContact CB-CD1 4.12Å; W147-Y152 HydrophobicContact CB-CE1 3.96Å; W147-Y152 HydrophobicContact CE3-CD1 4.07Å; W147-Y152 AromaticContact CE3-CD2 3.39Å; W147-Y152 HydrophobicContact CE3-CD2 3.39Å; W147-Y152 HydrophobicContact CE3-CE1 4.1Å; W147-Y152 AromaticContact CE3-CE2 3.43Å; W147-Y152 HydrophobicContact CE3-CE2 3.43Å; W147-Y152 VanDerWaalsContact CE3-CE2 3.43Å; W147-Y152 AromaticContact CE3-CG 3.71Å; W147-Y152 HydrophobicContact CE3-CG 3.71Å; W147-Y152 AromaticContact CE3-CZ 3.79Å; W147-Y152 AromaticContact CZ3-CD2 3.59Å; W147-Y152 HydrophobicContact CZ3-CD2 3.59Å; W147-Y152 AromaticContact CZ3-CE2 3.67Å; W147-Y152 HydrophobicContact CZ3-CE2 3.67Å; W147-Y152 HydrophobicContact CZ3-CG 4.3Å; Y152-C154 PolarHBondContact O-N 3Å; Y152-C155 PolarHBondContact O-N 2.83Å; Y152-S156 VanDerWaalsContact O-CA 3.31Å; Y152-S156 WeakPolarHBondContact O-CA 3.41Å; Y152-S156 PolarHBondContact O-N 3Å; Y152-Q157 HydrophobicContact CD2-CB 4.26Å; Y152-Q157 PolarHBondContact N-O 3.26Å; Y152-A159 WeakPolarHBondContact CE2-O 3.29Å; Y152-K160 PolarHBondContact OH-O 2.87Å
153L91.2Very high88.7Confident97 Ų9756.6 Ų56.651%0.50832%0.322SS..THydrogen-bonded Turntrans-66.1-18.2-179.6-66.2-179.9000114.2C145 F146 I148C145-L153 HydrophobicContact CB-CB 3.85Å; F146-L153 HydrophobicContact CB-CD1 4.5Å; F146-L153 WeakPolarHBondContact O-CG 3.49Å; F146-L153 PolarHBondContact O-N 2.87Å; I148-L153 HydrophobicContact CD1-CD1 3.88Å; I148-L153 HydrophobicContact CG1-CD1 4.19Å; I148-L153 HydrophobicContact CG1-CG 4.48Å
154C89.9Confident88.6Confident43 Ų4356.6 Ų56.629%0.29132%0.324SS..THydrogen-bonded Turntrans-81.7-27.1-179.145.90000114.1P144 C145 Y152P144-C154 HydrophobicContact CG-CB 3.8Å; C145-C154 HydrophobicContact CB-CB 3.71Å; Y152-C154 PolarHBondContact O-N 3Å
155C89.6Confident88.4Confident42 Ų4258.7 Ų58.728%0.28434%0.338SS..THydrogen-bonded Turntrans-149.77.1-171.162.60000114.5H143 Y152 Q157 C165H143-C155 VanDerWaalsContact CE1-SG 3.56Å; Y152-C155 PolarHBondContact O-N 2.83Å; C155-Q157 HydrophobicContact CB-CG 4.47Å; C155-Q157 PolarHBondContact O-N 3.03Å; C155-Q157 VanDerWaalsContact SG-CG 3.55Å; C155-Q157 PolarHBondContact SG-NE2 2.86Å; C155-C165 HydrophobicContact CB-CB 3.71Å
156S91.4Very high88.3Confident79 Ų7961.2 Ų61.255%0.55235%0.348SS*.  trans57.419.7178.6-54.70000115.2Y152Y152-S156 VanDerWaalsContact O-CA 3.31Å; Y152-S156 WeakPolarHBondContact O-CA 3.41Å; Y152-S156 PolarHBondContact O-N 3Å
157Q88.8Confident88.1Confident62 Ų6266.5 Ų66.529%0.2938%0.375SS..  trans-70.4133.7174.8-72.3-176.961.600109.5W147 Q151 Y152 C155 A162 M163W147-Q157 WeakPolarHBondContact CZ3-O 3.33Å; Q151-Q157 CarbonylContact C-O 3.52Å; Q151-Q157 VanDerWaalsContact CA-O 3.24Å; Q151-Q157 WeakPolarHBondContact CA-O 3.34Å; Y152-Q157 HydrophobicContact CD2-CB 4.26Å; Y152-Q157 PolarHBondContact N-O 3.26Å; C155-Q157 HydrophobicContact CB-CG 4.47Å; C155-Q157 PolarHBondContact O-N 3.03Å; C155-Q157 VanDerWaalsContact SG-CG 3.55Å; C155-Q157 PolarHBondContact SG-NE2 2.86Å; Q157-A162 HydrophobicContact CB-CB 4.14Å; Q157-M163 PolarHBondContact NE2-O 2.81Å; Q157-M163 VanDerWaalsContact NE2-O 3.16Å; Q157-M163 PolarHBondContact OE1-O 3.09Å
158T90Very high87.9Confident110 Ų11067.2 Ų67.268%0.67538%0.38SS*.  trans-103.912.3-170.555.90000114.5W147 G150 Q151W147-T158 WeakPolarHBondContact CH2-O 3.5Å; G150-T158 VanDerWaalsContact O-CA 3.31Å; G150-T158 WeakPolarHBondContact O-CA 3.39Å; Q151-T158 HydrophobicContact CB-CG2 4.27Å
159A86.4Confident87.2Confident42 Ų4274.1 Ų74.135%0.34741%0.412SS..  trans-118.7132.4170.400000111.1W147 Y152 N161 A162W147-A159 WeakPolarHBondContact CZ3-O 3.34Å; Y152-A159 WeakPolarHBondContact CE2-O 3.29Å; A159-N161 VanDerWaalsContact C-N 3.29Å; A159-N161 PolarHBondContact O-N 2.79Å; A159-A162 HydrophobicContact CB-CB 4.12Å; A159-A162 WeakPolarHBondContact O-CB 3.23Å; A159-A162 PolarHBondContact O-N 3.25Å; A159-A162 VanDerWaalsContact O-N 3.09Å
160K84.5Confident85.4Confident60 Ų6074.7 Ų74.726%0.26142%0.415SS..THydrogen-bonded Turntrans-65.1-33.4-176.3-76.6-173.1-177.5176.10112.8Q15 Q16 W147 Y152 A162Q15-K160 PolarHBondContact O-NZ 2.76Å; Q16-K160 PolarHBondContact O-NZ 3.29Å; W147-K160 HydrophobicContact CD2-CG 3.72Å; W147-K160 VanDerWaalsContact CE2-CG 3.41Å; W147-K160 HydrophobicContact CE3-CG 4.09Å; W147-K160 HydrophobicContact CG-CG 4.28Å; W147-K160 HydrophobicContact CH2-CB 4.43Å; W147-K160 HydrophobicContact CH2-CG 3.79Å; W147-K160 HydrophobicContact CZ2-CD 4.45Å; W147-K160 HydrophobicContact CZ2-CG 3.45Å; W147-K160 VanDerWaalsContact CZ2-CG 3.45Å; W147-K160 HydrophobicContact CZ3-CG 4.14Å; W147-K160 VanDerWaalsContact NE1-CE 3.31Å; Y152-K160 PolarHBondContact OH-O 2.87Å; K160-A162 VanDerWaalsContact C-N 3.27Å
161N85.2Confident83.3Confident143 Ų14385.5 Ų85.577%0.76545%0.449SS*.THydrogen-bonded Turntrans-87.57.9177.264.2-22.4000112.8A159A159-N161 VanDerWaalsContact C-N 3.29Å; A159-N161 PolarHBondContact O-N 2.79Å
162A85.2Confident80.6Confident23 Ų2389 Ų8919%0.1947%0.471CS..SBendtrans-66.3144.7179.500000110.8H143 Q157 A159 K160H143-A162 PolarHBondContact NE2-O 2.84Å; Q157-A162 HydrophobicContact CB-CB 4.14Å; A159-A162 HydrophobicContact CB-CB 4.12Å; A159-A162 WeakPolarHBondContact O-CB 3.23Å; A159-A162 PolarHBondContact O-N 3.25Å; A159-A162 VanDerWaalsContact O-N 3.09Å; K160-A162 VanDerWaalsContact C-N 3.27Å
163M87.4Confident77.6Confident139 Ų13992.4 Ų92.469%0.68551%0.507SS*.PPolyproline II helixtrans-57.4139.3-177.2-173.9178.5-69.300111.3K141 H143 Q157K141-M163 HydrophobicContact CD-CG 4.49Å; K141-M163 HydrophobicContact CD-SD 4.39Å; H143-M163 PolarHBondContact CE1-O 2.85Å; H143-M163 PolarHBondContact NE2-O 3.31Å; Q157-M163 PolarHBondContact NE2-O 2.81Å; Q157-M163 VanDerWaalsContact NE2-O 3.16Å; Q157-M163 PolarHBondContact OE1-O 3.09Å
164G89.9Confident74.9Confident9 Ų993.8 Ų93.89%0.09352%0.524CS..PPolyproline II helixtrans-55.2146.8178.100000113.7K141 Y142K141-G164 VanDerWaalsContact CB-O 3.31Å; K141-G164 WeakPolarHBondContact CB-O 3.34Å; K141-G164 WeakPolarHBondContact CD-O 3.39Å; Y142-G164 VanDerWaalsContact C-CA 3.44Å; Y142-G164 CarbonylContact O-C 3.42Å; Y142-G164 WeakPolarHBondContact O-CA 3.38Å
165C88.1Confident72.1Confident60 Ų6099.7 Ų99.741%0.40555%0.552SS.*SBendtrans-91.7-11.4178.565.50000114.5Y142 C155Y142-C165 PolarHBondContact O-N 3.41Å; C155-C165 HydrophobicContact CB-CB 3.71Å
166Q90.1Very high69.3Low80 Ų80107.1 Ų107.137%0.37458%0.579SS.*EExtended strand (participates in β ladder)trans-121.9138.9179.6-175.2170.5-21.700111.2K141 Y142 P144K141-Q166 CarbonylContact C-O 3.54Å; K141-Q166 WeakPolarHBondContact CA-O 3.47Å; K141-Q166 WeakPolarHBondContact CB-O 3.48Å; Y142-Q166 HydrophobicContact CD1-CB 4.36Å; Y142-Q166 WeakPolarHBondContact CD1-O 3.5Å; Y142-Q166 HydrophobicContact CE1-CB 4.03Å; Y142-Q166 HydrophobicContact CE1-CG 3.89Å; Y142-Q166 PolarHBondContact N-O 2.73Å; Y142-Q166 PolarHBondContact O-N 3.17Å; Y142-Q166 PolarHBondContact OH-NE2 2.76Å; P144-Q166 HydrophobicContact CG-CB 4.4Å
167I88.4Confident66.5Low114 Ų114109.6 Ų109.659%0.58559%0.594SS**EExtended strand (participates in β ladder)trans-76.3139.7178.3-60.4170.8000109.6K141 E169K141-I167 HydrophobicContact CG-CG1 4.19Å; I167-E169 PolarHBondContact O-N 3.47Å
168L84.1Confident63.6Low38 Ų38110.1 Ų110.120%0.19962%0.616CS.*  trans-71.7120.6170.3-72.6166.5000109.7E65 V139 Q140 Y142 N170E65-L168 HydrophobicContact CB-CD2 4.47Å; E65-L168 HydrophobicContact CG-CD2 4.3Å; V139-L168 WeakPolarHBondContact O-CD1 3.32Å; Q140-L168 PolarHBondContact O-N 2.81Å; Y142-L168 HydrophobicContact CD1-CD2 3.56Å; Y142-L168 HydrophobicContact CD1-CG 3.91Å; Y142-L168 HydrophobicContact CE1-CD2 3.94Å; Y142-L168 HydrophobicContact CG-CD2 4.15Å; L168-N170 PolarHBondContact O-N 2.66Å; L168-N170 VanDerWaalsContact O-N 3.11Å
169E70.9Confident60.9Low181 Ų181110.8 Ų110.885%0.84663%0.625SS**  trans-72.9102.9174.1-64.8-173.7167.300109.6I167I167-E169 PolarHBondContact O-N 3.47Å
170N47.6Very low58.2Low144 Ų144114.1 Ų114.177%0.7765%0.646SS**  trans-83.8138.9168.9-95.4-7.5000109.9L168 N172L168-N170 PolarHBondContact O-N 2.66Å; L168-N170 VanDerWaalsContact O-N 3.11Å; N170-N172 PolarHBondContact O-N 2.94Å
171R40.3Very low55.8Low247 Ų247120 Ų12093%0.93267%0.674SS**SBendtrans-74.748.7-176.8-146.4-174.9-169-164.12.1113
172N31.8Very low53.4Low153 Ų153124.9 Ų124.982%0.81868%0.681SS**SBendtrans-142.1116165.6-88-6.7000109N170N170-N172 PolarHBondContact O-N 2.94Å
173G29.8Very low50.9Low75 Ų75133.7 Ų133.777%0.77372%0.716SS**  trans70.499.415300000116.6L175G173-L175 PolarHBondContact O-N 3.21Å
174S33.7Very low48.2Very low125 Ų125133.4 Ų133.487%0.87472%0.722SS**  trans-46.9121.1165.4-440000112.8
175L30.9Very low45.4Very low167 Ų167142.8 Ų142.887%0.87476%0.76SS**  trans-129.6108.3154-84.8160.1000107.4G173G173-L175 PolarHBondContact O-N 3.21Å
176K30.3Very low42.7Very low198 Ų198149.6 Ų149.686%0.86178%0.783SS**  trans-61.8136.6171.9-67.1-176.3177.1-179.50108.8G178K176-G178 PolarHBondContact O-N 3.1Å
177P32.9Very low40.2Very low131 Ų131151.5 Ų151.585%0.85180%0.802SS**  trans-77108.517226.7-24000109.1
178G27.9Very low37.7Very low73 Ų73153.9 Ų153.975%0.75382%0.815SS**  trans-63.1131.4161.400000110.1K176 S180K176-G178 PolarHBondContact O-N 3.1Å; G178-S180 PolarHBondContact O-N 3.2Å
179S32.8Very low35.6Very low125 Ų125157.5 Ų157.587%0.87484%0.841SS**  trans-47128.8165.8174.30000111.4
180S30.6Very low33.9Very low111 Ų111154.5 Ų154.578%0.77684%0.837SS**  trans-159.6107.1148-1710000111.6G178G178-S180 PolarHBondContact O-N 3.2Å
181H34.8Very low33.4Very low184 Ų184154 Ų15485%0.85284%0.839SS**  trans-62.4127.3154-88.6-25.1000110.3
182R33.3Very low33.5Very low245 Ų245147 Ų14793%0.92583%0.826SS**  trans-164.4136.7130.5-117.2171.4-178.8-172.9-0.3114.1
183K32.6Very low33.4Very low209 Ų209147.7 Ų147.791%0.90982%0.824SS**  trans-71.2145.2178.7-65.8171.9175.7174.90111.2
184T30.7Very low33.4Very low132 Ų132151.4 Ų151.481%0.8182%0.821SS**  trans-83.3140.1168.2460000111.5
185K32.5Very low33.1Very low207 Ų207151.8 Ų151.890%0.981%0.814SS**  trans-151.6118.1148.3-74.1-161.9177.9179.50110.3
186K31Very low33Very low203 Ų203153.4 Ų153.488%0.88382%0.817SS**  trans-6.7173.6151.8-74.7-178.5176.3-175.60120.1
187P38.3Very low32.9Very low120 Ų120151.1 Ų151.178%0.77981%0.812SS**  cis-138.6179.5-18.529.5-5.6000116
188L34.5Very low32.7Very low164 Ų164151.5 Ų151.586%0.85981%0.807SS**  trans-66.2166.3163-74.3160.2000112.4
189P40.2Very low32.6Very low114 Ų114157.1 Ų157.174%0.7481%0.81SS**  cis-152.3-149.846.444-20.2000113.6
190P36.1Very low32.3Very low118 Ų118160.6 Ų160.677%0.76681%0.81SS**  cis-130.3178.9-21.136.2-15.9000115.4
191T35.7Very low32.2Very low133 Ų133160.9 Ų160.982%0.81681%0.809SS**  trans-95.7158.5160.830.60000111.2
192P43Very low31.8Very low100 Ų100160 Ų16065%0.64981%0.809SS**  -152.6146.9100.634.4-12.9000116.3
193E30.6Very low32Very low167 Ų167153.6 Ų153.678%0.7880%0.799SS**  82145.7116.3-69.9168.4-169.700115
194E28.8Very low32.3Very low153 Ų153149.3 Ų149.372%0.71579%0.793SS**  cis-165.6156.12.6-118.1172.9178.600109.2
195D28.2Very low32.4Very low134 Ų134151.8 Ų151.872%0.71780%0.795SS**  trans52.2120151.5-69.1-16.8000124.8
196Q28.6Very low32.7Very low200 Ų200147.9 Ų147.994%0.93579%0.791SS**  -167.6152.8116.5-103171.242.100113.4
197I29.1Very low33Very low150 Ų150142.6 Ų142.677%0.76979%0.785SS**  trans-94.9152.5-157.3-74.6169.7000113.3
198L27.1Very low33.1Very low140 Ų140141.9 Ų141.973%0.73379%0.79SS**  trans88.2114.8157.4-76.7155.2000122
199K25.6Very low33.1Very low190 Ų190138 Ų13883%0.82678%0.781SS**  trans68.8113141.1-70.7177.4-177.3178.10120.8
200K26.7Very low33Very low199 Ų199138.3 Ų138.387%0.86578%0.784SS**  trans-25.1121.5164.2-156.7176.9-169.5-179.40117.2
201P28.7Very low33Very low117 Ų117139.2 Ų139.276%0.7679%0.786SS**PPolyproline II helixtrans-87.1145.6154.4-1.821000111
202L27.7Very low32.9Very low165 Ų165137.6 Ų137.686%0.86478%0.781SS**PPolyproline II helixtrans-62.2141.2174.7-75.8153.8000111.1
203P36.9Very low32.7Very low110 Ų110139.3 Ų139.371%0.71479%0.789SS**PPolyproline II helixtrans-62.3142169.4-16.829.6000110.9
204P37.6Very low33.2Very low120 Ų120135.3 Ų135.378%0.77978%0.78SS**PPolyproline II helixtrans-66.4155.1176.428.4-32.9000111.4
205E33.4Very low34.3Very low183 Ų183137.3 Ų137.386%0.85579%0.789SS**  trans-39.5126173.7-119.7172.3173.400111.5A207E205-A207 PolarHBondContact O-N 3.1Å
206P39.8Very low36.2Very low125 Ų125134 Ų13481%0.81277%0.771SS**  trans-66.4112173.923.9-28.2000108.8A208P206-A208 PolarHBondContact O-N 3.24Å
207A37.5Very low38.6Very low92 Ų92127.3 Ų127.376%0.7674%0.739SS**  trans-49.7133.9161.300000109E205 A209E205-A207 PolarHBondContact O-N 3.1Å; A207-A209 PolarHBondContact O-N 2.9Å
208A39.3Very low41.3Very low105 Ų105123.9 Ų123.987%0.86872%0.719SS**  trans-45.9114.2179.900000111.2P206P206-A208 PolarHBondContact O-N 3.24Å
209A34.4Very low44.2Very low83 Ų83117.3 Ų117.369%0.68668%0.684SS**  trans-68.5145.5167.100000109.1A207 V211A207-A209 PolarHBondContact O-N 2.9Å; A209-V211 PolarHBondContact O-N 2.99Å
210P38.5Very low47.1Very low121 Ų121109.7 Ų109.779%0.78665%0.653SS**  trans-64.2135.6-179.127.8-33.5000110S212P210-S212 PolarHBondContact O-N 3.47Å
211V36.9Very low49.9Very low136 Ų136100.3 Ų100.382%0.82461%0.613SS**  trans-59.6100.1169.8-179.60000107.8A209 T213A209-V211 PolarHBondContact O-N 2.99Å; V211-T213 PolarHBondContact O-N 2.74Å
212S33.2Very low52.2Low100 Ų10096.7 Ų96.770%0.69959%0.587SS**  trans-72113.6161.656.20000107P210 S214P210-S212 PolarHBondContact O-N 3.47Å; S212-S214 PolarHBondContact O-N 3.22Å
213T37.7Very low54.5Low135 Ų13595.2 Ų95.283%0.82857%0.571SS**  trans-63.984.8164.346.40000108.4V211V211-T213 PolarHBondContact O-N 2.74Å
214S41.6Very low56.6Low83 Ų8395.3 Ų95.358%0.5857%0.566SS**  trans-70.7128.6161.256.80000107.3S212 L216S212-S214 PolarHBondContact O-N 3.22Å; S214-L216 PolarHBondContact O-N 3.38Å
215E51.3Low58.9Low195 Ų19590.3 Ų90.391%0.91153%0.531SS*.  trans-50.5113166.2-71.1175.7147.400108.1K217E215-K217 PolarHBondContact O-N 3.24Å
216L68.2Low61.5Low64 Ų6488 Ų8834%0.33552%0.522SS..PPolyproline II helixtrans-66127.5-179.4-68.7169.4000108.5S214 K218 F242 L244S214-L216 PolarHBondContact O-N 3.38Å; L216-K218 PolarHBondContact O-N 3.45Å; L216-F242 HydrophobicContact CB-CB 4.04Å; L216-F242 HydrophobicContact CB-CD1 4.16Å; L216-F242 HydrophobicContact CD1-CB 4.31Å; L216-L244 HydrophobicContact CD1-CD2 3.87Å; L216-L244 HydrophobicContact CD2-CD2 3.86Å
217K79.3Confident63.7Low61 Ų6184.9 Ų84.927%0.26550%0.502SS..EExtended strand (participates in β ladder)trans-59119.9-179.8177.5178-178.4170.50110E215 I243 E246 E271E215-K217 PolarHBondContact O-N 3.24Å; K217-I243 HydrophobicContact CB-CB 4.27Å; K217-I243 PolarHBondContact O-N 3.4Å; K217-E246 IonicContact NZ-OE1 2.67Å; K217-E246 PolarHBondContact NZ-OE1 3.3Å; K217-E246 IonicContact NZ-OE2 3.73Å; K217-E246 PolarHBondContact NZ-OE2 2.85Å; K217-E271 WeakPolarHBondContact CE-OE1 3.45Å; K217-E271 IonicContact NZ-OE1 3.61Å; K217-E271 PolarHBondContact NZ-OE1 2.76Å
218K86.4Confident65.8Low78 Ų7888 Ų8834%0.33950%0.503SS..EExtended strand (participates in β ladder)trans-92.6130.4-176.8-168.3-178.2-179.2-169.50110.9L216 E240 Y241 F242 A272L216-K218 PolarHBondContact O-N 3.45Å; K218-E240 WeakPolarHBondContact CE-OE1 3.01Å; K218-E240 WeakPolarHBondContact CE-OE2 3.33Å; K218-E240 IonicContact NZ-OE1 3.75Å; K218-E240 PolarHBondContact NZ-OE1 3.18Å; K218-E240 IonicContact NZ-OE2 2.83Å; K218-E240 PolarHBondContact NZ-OE2 2.99Å; K218-Y241 WeakPolarHBondContact CA-O 3.38Å; K218-F242 HydrophobicContact CB-CD1 4.28Å; K218-F242 HydrophobicContact CB-CE1 4.2Å; K218-F242 HydrophobicContact CD-CE1 4.14Å; K218-F242 HydrophobicContact CD-CZ 4.47Å; K218-F242 HydrophobicContact CG-CD1 4.32Å; K218-F242 HydrophobicContact CG-CE1 3.96Å; K218-F242 HydrophobicContact CG-CZ 4.48Å; K218-A272 HydrophobicContact CB-CB 4.22Å; K218-A272 HydrophobicContact CD-CB 4.2Å; K218-A272 HydrophobicContact CG-CB 4Å; K218-A272 WeakPolarHBondContact O-CB 3.27Å; K218-A272 PolarHBondContact O-N 3.47Å; K218-A272 VanDerWaalsContact O-N 3.14Å
219V86.4Confident68Low1 Ų186.7 Ų86.71%0.00648%0.481CS..EExtended strand (participates in β ladder)trans-129.6157.4-179.8-59.70000111.2E240 Y241 I243 V269 T270V219-E240 CarbonylContact O-C 3.45Å; V219-E240 WeakPolarHBondContact O-CA 3.18Å; V219-Y241 PolarHBondContact N-O 2.84Å; V219-Y241 PolarHBondContact O-N 3.37Å; V219-I243 HydrophobicContact CG1-CD1 4.2Å; V219-I243 HydrophobicContact CG1-CG1 3.76Å; V219-I243 HydrophobicContact CG2-CD1 3.67Å; V219-I243 HydrophobicContact CG2-CG1 4.02Å; V219-V269 HydrophobicContact CB-CB 4.08Å; V219-V269 HydrophobicContact CB-CG2 4.36Å; V219-V269 HydrophobicContact CG2-CB 3.91Å; V219-V269 HydrophobicContact CG2-CG1 4.17Å; V219-V269 HydrophobicContact CG2-CG2 4.11Å; V219-T270 CarbonylContact C-O 3.59Å; V219-T270 WeakPolarHBondContact CA-O 3.3Å; V219-T270 WeakPolarHBondContact CB-O 3.38Å
220V87Confident70.3Confident30 Ų3087.8 Ų87.818%0.18249%0.49CS..EExtended strand (participates in β ladder)trans-117.1137.2177.4-177.20000109.5L222 D239 E240 V269 T270 A272V220-L222 PolarHBondContact O-N 2.96Å; V220-D239 WeakPolarHBondContact CA-O 3.12Å; V220-E240 HydrophobicContact CG2-CG 4.32Å; V220-V269 CarbonylContact O-C 3.59Å; V220-V269 VanDerWaalsContact O-CA 3.25Å; V220-V269 WeakPolarHBondContact O-CA 3.37Å; V220-T270 HydrophobicContact CB-CG2 4.4Å; V220-T270 PolarHBondContact N-O 2.92Å; V220-T270 PolarHBondContact O-N 2.64Å; V220-A272 HydrophobicContact CG2-CB 3.94Å
221A86.4Confident72.5Confident2 Ų287.2 Ų87.22%0.01748%0.481CS..EExtended strand (participates in β ladder)trans-74124.5176.600000112.5L235 R236 G238 D239 Y241 Y268 V269A221-L235 HydrophobicContact CB-CB 3.99Å; A221-L235 HydrophobicContact CB-CD2 4.3Å; A221-R236 VanDerWaalsContact CB-O 3.3Å; A221-R236 WeakPolarHBondContact CB-O 3.09Å; A221-G238 PolarHBondContact O-N 3.38Å; A221-D239 PolarHBondContact N-O 2.91Å; A221-Y241 HydrophobicContact CB-CD2 4.37Å; A221-Y241 HydrophobicContact CB-CE2 3.9Å; A221-Y268 WeakPolarHBondContact CA-O 3.46Å; A221-V269 HydrophobicContact CB-CG1 4.47Å
222L76.4Confident75Confident41 Ų4181.7 Ų81.722%0.21545%0.446CS..SBendtrans-79.1-27.9175.6-65.1176.9000112.4V220 K237 Y268 T270V220-L222 PolarHBondContact O-N 2.96Å; L222-K237 WeakPolarHBondContact O-CD 3.38Å; L222-K237 WeakPolarHBondContact O-CE 3.48Å; L222-K237 WeakPolarHBondContact O-CG 3.49Å; L222-Y268 PolarHBondContact N-O 3.45Å; L222-T270 HydrophobicContact CD2-CG2 3.65Å; L222-T270 HydrophobicContact CG-CG2 4.15Å
223Y75.9Confident77.7Confident134 Ų13477 Ų7753%0.52541%0.414SS..SBendtrans-140.8156.4-176-49.1-75000110.9Y268Y223-Y268 HydrophobicContact CD2-CD1 4.25Å; Y223-Y268 HydrophobicContact CD2-CG 4.3Å; Y223-Y268 HydrophobicContact CG-CD1 4.47Å
224D81.8Confident80.3Confident113 Ų11373.7 Ų73.760%0.60439%0.388SS*.  trans-71.1139.3169.3-62.2-43.3000110.3L235 R236 K237D224-L235 WeakPolarHBondContact CA-O 3.31Å; D224-R236 WeakPolarHBondContact OD1-CA 3.38Å; D224-K237 WeakPolarHBondContact OD1-CB 3.3Å; D224-K237 PolarHBondContact OD1-N 3.17Å
225Y85.9Confident82.6Confident15 Ų1569.8 Ų69.86%0.05936%0.361CS..BIsolated β-bridgetrans-137.3126175.3173.9-101.3000110.3M228 D232 L233 Q234 L235 W251 P265 Y268Y225-M228 HydrophobicContact CE2-CE 4.34Å; Y225-D232 HydrophobicContact CE1-CB 4.12Å; Y225-D232 PolarHBondContact OH-OD2 3.35Å; Y225-L233 WeakPolarHBondContact CD1-O 3.46Å; Y225-Q234 WeakPolarHBondContact O-CA 3.27Å; Y225-Q234 WeakPolarHBondContact O-CG 3.42Å; Y225-L235 PolarHBondContact N-O 3.05Å; Y225-L235 PolarHBondContact O-N 2.7Å; Y225-W251 HydrophobicContact CE1-CZ3 4.29Å; Y225-W251 HydrophobicContact CE2-CH2 4.25Å; Y225-W251 AromaticContact CZ-CH2 3.81Å; Y225-W251 AromaticContact CZ-CZ3 3.97Å; Y225-W251 VanDerWaalsContact OH-CH2 3.3Å; Y225-W251 WeakPolarHBondContact OH-CH2 3.41Å; Y225-P265 HydrophobicContact CD1-CG 4.46Å; Y225-P265 HydrophobicContact CD2-CG 3.95Å; Y225-P265 HydrophobicContact CE1-CG 4.48Å; Y225-P265 HydrophobicContact CE2-CG 3.99Å; Y225-P265 HydrophobicContact CG-CG 4.22Å; Y225-Y268 HydrophobicContact CD2-CE1 4.38Å
226M86.4Confident84.3Confident133 Ų13367.1 Ų67.166%0.65534%0.343SS*.  trans-96.2129.8176.3-67.5-69-98.500109.6M228 Q234M226-M228 PolarHBondContact O-N 3.29Å; M226-Q234 PolarHBondContact SD-NE2 3.36Å
227P87.9Confident85.1Confident60 Ų6071.2 Ų71.239%0.3936%0.358SS..  trans-52.4127.1177.6-28.836.8000111.9D232 Q234P227-D232 HydrophobicContact CB-CB 3.89Å; P227-Q234 HydrophobicContact CG-CB 3.86Å
228M79.8Confident85Confident158 Ų15870.6 Ų70.678%0.77837%0.369SS*.SBendtrans-92.2-24.6177.3-67.1-176176.500111.9Y225 M226 D232Y225-M228 HydrophobicContact CE2-CE 4.34Å; M226-M228 PolarHBondContact O-N 3.29Å; M228-D232 WeakPolarHBondContact CA-OD2 3.36Å; M228-D232 WeakPolarHBondContact CB-OD2 3.34Å; M228-D232 PolarHBondContact N-OD2 2.74Å
229N86Confident85Confident77 Ų7769 Ų6941%0.41236%0.364SS..SBendtrans-140.3172.2175.168.975.8000111.3N231 D232N229-N231 PolarHBondContact O-N 3Å; N229-N231 VanDerWaalsContact O-N 3.15Å; N229-N231 WeakPolarHBondContact OD1-CA 3.31Å; N229-N231 VanDerWaalsContact OD1-CB 3.28Å; N229-N231 WeakPolarHBondContact OD1-CB 3.31Å; N229-N231 PolarHBondContact OD1-N 3.29Å; N229-D232 PolarHBondContact N-OD2 3.32Å; N229-D232 PolarHBondContact ND2-OD1 3.45Å; N229-D232 PolarHBondContact ND2-OD2 3.42Å; N229-D232 PolarHBondContact O-N 2.87Å; N229-D232 VanDerWaalsContact O-N 3.12Å; N229-D232 PolarHBondContact OD1-OD1 3.11Å
230A82.5Confident85.2Confident107 Ų10773.1 Ų73.188%0.88438%0.383SS*.THydrogen-bonded Turntrans-67.1-13.1-17500000114.7
231N84.9Confident85.3Confident109 Ų10972 Ų7258%0.58338%0.376SS*.THydrogen-bonded Turntrans-94.4-7.5177.3-53.8-47.2000112.4N229 G262 Y263N229-N231 PolarHBondContact O-N 3Å; N229-N231 VanDerWaalsContact O-N 3.15Å; N229-N231 WeakPolarHBondContact OD1-CA 3.31Å; N229-N231 VanDerWaalsContact OD1-CB 3.28Å; N229-N231 WeakPolarHBondContact OD1-CB 3.31Å; N229-N231 PolarHBondContact OD1-N 3.29Å; N231-G262 CarbonylContact O-C 3.43Å; N231-G262 VanDerWaalsContact O-CA 3.29Å; N231-G262 WeakPolarHBondContact O-CA 3.43Å; N231-Y263 HydrophobicContact CB-CD2 4.11Å; N231-Y263 WeakPolarHBondContact O-CD2 3.25Å; N231-Y263 PolarHBondContact O-N 3.44Å
232D89.3Confident85.6Confident19 Ų1975.3 Ų75.310%0.10239%0.39CS..BIsolated β-bridgetrans-87.2147.2-178.1-59.9-17.4000111.5Y225 P227 M228 N229 Y263Y225-D232 HydrophobicContact CE1-CB 4.12Å; Y225-D232 PolarHBondContact OH-OD2 3.35Å; P227-D232 HydrophobicContact CB-CB 3.89Å; M228-D232 WeakPolarHBondContact CA-OD2 3.36Å; M228-D232 WeakPolarHBondContact CB-OD2 3.34Å; M228-D232 PolarHBondContact N-OD2 2.74Å; N229-D232 PolarHBondContact N-OD2 3.32Å; N229-D232 PolarHBondContact ND2-OD1 3.45Å; N229-D232 PolarHBondContact ND2-OD2 3.42Å; N229-D232 PolarHBondContact O-N 2.87Å; N229-D232 VanDerWaalsContact O-N 3.12Å; N229-D232 PolarHBondContact OD1-OD1 3.11Å; D232-Y263 CarbonylContact C-O 3.59Å; D232-Y263 WeakPolarHBondContact CA-O 3.48Å
233L90.9Very high86.2Confident3 Ų373.7 Ų73.72%0.01638%0.381CS..  trans-105139.3176-177.468.5000110.7Y225 Y241 A254 D256 Q260 Y263 I264Y225-L233 WeakPolarHBondContact CD1-O 3.46Å; L233-Y241 HydrophobicContact CD2-CD1 3.9Å; L233-Y241 HydrophobicContact CD2-CE1 4.14Å; L233-Y241 HydrophobicContact CG-CE1 4.5Å; L233-A254 HydrophobicContact CD2-CB 4.27Å; L233-D256 HydrophobicContact CD1-CB 4.4Å; L233-D256 HydrophobicContact CD2-CB 4.35Å; L233-Q260 HydrophobicContact CD1-CB 4.03Å; L233-Q260 HydrophobicContact CD1-CG 3.82Å; L233-Y263 PolarHBondContact N-O 3.46Å; L233-I264 HydrophobicContact CB-CG2 3.71Å; L233-I264 HydrophobicContact CD2-CG2 4.09Å; L233-I264 HydrophobicContact CG-CG2 4.24Å
234Q91.6Very high86.7Confident64 Ų6469.3 Ų69.330%0.29937%0.367SS..  trans-71.3129.6179-174179.346.300110.8Y225 M226 P227 Y241Y225-Q234 WeakPolarHBondContact O-CA 3.27Å; Y225-Q234 WeakPolarHBondContact O-CG 3.42Å; M226-Q234 PolarHBondContact SD-NE2 3.36Å; P227-Q234 HydrophobicContact CG-CB 3.86Å; Q234-Y241 WeakPolarHBondContact O-CE1 3.4Å; Q234-Y241 PolarHBondContact O-OH 3.18Å
235L90.2Very high86.7Confident2 Ų268.7 Ų68.71%0.0136%0.36CS..BIsolated β-bridgetrans-99.7136.4167.2-57.2174.9000110.9A221 D224 Y225 Y241 I264 Y268 V269A221-L235 HydrophobicContact CB-CB 3.99Å; A221-L235 HydrophobicContact CB-CD2 4.3Å; D224-L235 WeakPolarHBondContact CA-O 3.31Å; Y225-L235 PolarHBondContact N-O 3.05Å; Y225-L235 PolarHBondContact O-N 2.7Å; L235-Y241 VanDerWaalsContact CA-OH 3.28Å; L235-Y241 WeakPolarHBondContact CA-OH 3.49Å; L235-Y241 HydrophobicContact CD2-CD1 4.04Å; L235-Y241 HydrophobicContact CD2-CD2 3.77Å; L235-Y241 HydrophobicContact CD2-CE1 3.82Å; L235-Y241 HydrophobicContact CD2-CE2 3.57Å; L235-Y241 HydrophobicContact CD2-CG 4.03Å; L235-I264 HydrophobicContact CD1-CB 4.2Å; L235-I264 HydrophobicContact CD2-CB 4.09Å; L235-I264 HydrophobicContact CD2-CD1 4.1Å; L235-I264 HydrophobicContact CD2-CG2 3.65Å; L235-I264 HydrophobicContact CG-CB 4.29Å; L235-I264 HydrophobicContact CG-CG2 4.05Å; L235-Y268 HydrophobicContact CD1-CG 4.45Å; L235-V269 HydrophobicContact CD1-CG1 3.87Å; L235-V269 HydrophobicContact CD2-CG1 4.11Å
236R87.6Confident86Confident139 Ų13973.4 Ų73.453%0.52538%0.383SS..  trans-116.4127.8167.1-63.4-179-173.9-164.32108.4A221 D224 G238 D239 Y241A221-R236 VanDerWaalsContact CB-O 3.3Å; A221-R236 WeakPolarHBondContact CB-O 3.09Å; D224-R236 WeakPolarHBondContact OD1-CA 3.38Å; R236-G238 PolarHBondContact O-N 2.93Å; R236-D239 HydrophobicContact CB-CB 4.2Å; R236-D239 WeakPolarHBondContact O-CB 3.37Å; R236-D239 PolarHBondContact O-N 3.24Å; R236-Y241 PolarHBondContact N-OH 2.88Å
237K84.6Confident84.9Confident149 Ų14969.6 Ų69.665%0.64837%0.369SS*.THydrogen-bonded Turntrans-52.9125.7-178.7-179.2177.5-179.6-171.30110.3L222 D224 D239L222-K237 WeakPolarHBondContact O-CD 3.38Å; L222-K237 WeakPolarHBondContact O-CE 3.48Å; L222-K237 WeakPolarHBondContact O-CG 3.49Å; D224-K237 WeakPolarHBondContact OD1-CB 3.3Å; D224-K237 PolarHBondContact OD1-N 3.17Å; K237-D239 VanDerWaalsContact C-N 3.34Å
238G76.3Confident83.5Confident49 Ų4975.2 Ų75.251%0.50540%0.396SS..THydrogen-bonded Turntrans86.1-10-179.100000115.4A221 R236A221-G238 PolarHBondContact O-N 3.38Å; R236-G238 PolarHBondContact O-N 2.93Å
239D86.8Confident83Confident43 Ų4373 Ų7323%0.2339%0.387CS..  trans-76.9154.2172.2-88.7-29.2000111.2V220 A221 R236 K237 Y241 K257V220-D239 WeakPolarHBondContact CA-O 3.12Å; A221-D239 PolarHBondContact N-O 2.91Å; R236-D239 HydrophobicContact CB-CB 4.2Å; R236-D239 WeakPolarHBondContact O-CB 3.37Å; R236-D239 PolarHBondContact O-N 3.24Å; K237-D239 VanDerWaalsContact C-N 3.34Å; D239-Y241 HydrophobicContact CB-CE2 3.82Å; D239-Y241 WeakPolarHBondContact O-CD2 3.33Å; D239-Y241 WeakPolarHBondContact O-CE2 3.47Å; D239-K257 VanDerWaalsContact CG-NZ 3.34Å; D239-K257 IonicContact OD1-NZ 2.83Å; D239-K257 PolarHBondContact OD1-NZ 3.38Å; D239-K257 IonicContact OD2-NZ 3.19Å; D239-K257 PolarHBondContact OD2-NZ 2.95Å
240E90.1Very high82.7Confident88 Ų8873.2 Ų73.241%0.41139%0.392SS..EExtended strand (participates in β ladder)trans-101.2142-175.8-54.2179.2138.300111.6K218 V219 V220K218-E240 WeakPolarHBondContact CE-OE1 3.01Å; K218-E240 WeakPolarHBondContact CE-OE2 3.33Å; K218-E240 IonicContact NZ-OE1 3.75Å; K218-E240 PolarHBondContact NZ-OE1 3.18Å; K218-E240 IonicContact NZ-OE2 2.83Å; K218-E240 PolarHBondContact NZ-OE2 2.99Å; V219-E240 CarbonylContact O-C 3.45Å; V219-E240 WeakPolarHBondContact O-CA 3.18Å; V220-E240 HydrophobicContact CG2-CG 4.32Å
241Y90.6Very high82.7Confident8 Ų872.8 Ų72.83%0.03137%0.368CS..EExtended strand (participates in β ladder)trans-136.3152-177.8-60.4-94.5000110.4K218 V219 A221 L233 Q234 L235 R236 D239 R255 D256K218-Y241 WeakPolarHBondContact CA-O 3.38Å; V219-Y241 PolarHBondContact N-O 2.84Å; V219-Y241 PolarHBondContact O-N 3.37Å; A221-Y241 HydrophobicContact CB-CD2 4.37Å; A221-Y241 HydrophobicContact CB-CE2 3.9Å; L233-Y241 HydrophobicContact CD2-CD1 3.9Å; L233-Y241 HydrophobicContact CD2-CE1 4.14Å; L233-Y241 HydrophobicContact CG-CE1 4.5Å; Q234-Y241 WeakPolarHBondContact O-CE1 3.4Å; Q234-Y241 PolarHBondContact O-OH 3.18Å; L235-Y241 VanDerWaalsContact CA-OH 3.28Å; L235-Y241 WeakPolarHBondContact CA-OH 3.49Å; L235-Y241 HydrophobicContact CD2-CD1 4.04Å; L235-Y241 HydrophobicContact CD2-CD2 3.77Å; L235-Y241 HydrophobicContact CD2-CE1 3.82Å; L235-Y241 HydrophobicContact CD2-CE2 3.57Å; L235-Y241 HydrophobicContact CD2-CG 4.03Å; R236-Y241 PolarHBondContact N-OH 2.88Å; D239-Y241 HydrophobicContact CB-CE2 3.82Å; D239-Y241 WeakPolarHBondContact O-CD2 3.33Å; D239-Y241 WeakPolarHBondContact O-CE2 3.47Å; Y241-R255 WeakPolarHBondContact CA-O 3.2Å; Y241-D256 HydrophobicContact CD1-CB 4Å; Y241-D256 HydrophobicContact CE1-CB 3.83Å
242F91.1Very high83Confident70 Ų7069.7 Ų69.731%0.30735%0.348SS..EExtended strand (participates in β ladder)trans-110.1122178.9-62.9-83.3000110.2L216 K218 L244 A254 R255L216-F242 HydrophobicContact CB-CB 4.04Å; L216-F242 HydrophobicContact CB-CD1 4.16Å; L216-F242 HydrophobicContact CD1-CB 4.31Å; K218-F242 HydrophobicContact CB-CD1 4.28Å; K218-F242 HydrophobicContact CB-CE1 4.2Å; K218-F242 HydrophobicContact CD-CE1 4.14Å; K218-F242 HydrophobicContact CD-CZ 4.47Å; K218-F242 HydrophobicContact CG-CD1 4.32Å; K218-F242 HydrophobicContact CG-CE1 3.96Å; K218-F242 HydrophobicContact CG-CZ 4.48Å; F242-L244 PolarHBondContact O-N 3.43Å; F242-A254 CarbonylContact O-C 3.57Å; F242-A254 VanDerWaalsContact O-CA 3.24Å; F242-A254 WeakPolarHBondContact O-CA 3.45Å; F242-R255 PolarHBondContact N-O 3.45Å; F242-R255 PolarHBondContact O-N 3.29Å
243I90.8Very high82.9Confident7 Ų772.6 Ų72.64%0.03636%0.358CS..EExtended strand (participates in β ladder)trans-77.6122.1178.9-54.9-55.3000109.3K217 V219 E246 W252 A254 I264K217-I243 HydrophobicContact CB-CB 4.27Å; K217-I243 PolarHBondContact O-N 3.4Å; V219-I243 HydrophobicContact CG1-CD1 4.2Å; V219-I243 HydrophobicContact CG1-CG1 3.76Å; V219-I243 HydrophobicContact CG2-CD1 3.67Å; V219-I243 HydrophobicContact CG2-CG1 4.02Å; I243-E246 HydrophobicContact CG2-CB 4.2Å; I243-W252 HydrophobicContact CD1-CB 4.4Å; I243-W252 HydrophobicContact CD1-CE3 3.95Å; I243-W252 HydrophobicContact CG1-CE3 4.37Å; I243-A254 HydrophobicContact CD1-CB 3.93Å; I243-I264 HydrophobicContact CD1-CD1 4.06Å
244L86.4Confident83Confident43 Ų4372.5 Ų72.523%0.22536%0.357CS..EExtended strand (participates in β ladder)trans-91.5-40.3178.3-59.4177.2000111.5L216 F242 R253 R255 E261L216-L244 HydrophobicContact CD1-CD2 3.87Å; L216-L244 HydrophobicContact CD2-CD2 3.86Å; F242-L244 PolarHBondContact O-N 3.43Å; L244-R253 HydrophobicContact CD1-CG 4.42Å; L244-R253 PolarHBondContact N-O 3Å; L244-R255 HydrophobicContact CD1-CB 4.1Å; L244-R255 HydrophobicContact CD2-CB 4.24Å; L244-R255 HydrophobicContact CG-CB 4.2Å; L244-E261 HydrophobicContact CD1-CB 4.33Å; L244-E261 HydrophobicContact CD1-CG 3.75Å; L244-E261 WeakPolarHBondContact CD1-OE1 3.47Å
245E81.5Confident83Confident99 Ų9973.5 Ų73.546%0.46336%0.358SS..EExtended strand (participates in β ladder)trans-137.2113178.9-66171.5-145.900109.4R253E245-R253 HydrophobicContact CB-CB 4.1Å; E245-R253 PolarHBondContact N-O 3.22Å; E245-R253 PolarHBondContact O-N 2.96Å; E245-R253 IonicContact OE1-CZ 2.64Å; E245-R253 IonicContact OE1-NH1 2.81Å; E245-R253 PolarHBondContact OE1-NH1 3.16Å
246E70.1Confident83.1Confident114 Ų11474.3 Ų74.353%0.53336%0.363SS..  trans-91.4111.4172-164.4166.8-155.700108.3K217 I243 W252K217-E246 IonicContact NZ-OE1 2.67Å; K217-E246 PolarHBondContact NZ-OE1 3.3Å; K217-E246 IonicContact NZ-OE2 3.73Å; K217-E246 PolarHBondContact NZ-OE2 2.85Å; I243-E246 HydrophobicContact CG2-CB 4.2Å; E246-W252 HydrophobicContact CG-CZ2 4.34Å
247S64.6Low83Confident53 Ų5374 Ų7437%0.37137%0.365SS..  trans-114156.8175.3-174.40000109.5L249 W252S247-L249 PolarHBondContact O-N 2.71Å; S247-W252 PolarHBondContact O-NE1 2.81Å
248N57.1Low83Confident179 Ų17973.2 Ų73.296%0.95737%0.368SS*.SBendtrans-68.910.4172.4-61.8-30.7000113
249L70.8Confident83.4Confident111 Ų11173 Ų7358%0.58137%0.365SS*.SBendtrans-93.3154.7-179.9-65.3175.7000110.4S247 W251 W252S247-L249 PolarHBondContact O-N 2.71Å; L249-W251 PolarHBondContact O-N 2.82Å; L249-W252 PolarHBondContact O-NE1 2.88Å
250P79.8Confident83.4Confident81 Ų8176.8 Ų76.853%0.52638%0.382SS..SBendtrans-68.7-3.3-179.427.5-34.3000114.3P265 S266P250-P265 WeakPolarHBondContact O-CA 3.14Å; P250-S266 PolarHBondContact O-N 3.22Å; P250-S266 PolarHBondContact O-OG 2.93Å
251W82.8Confident83.6Confident99 Ų9976.2 Ų76.238%0.37538%0.379SS..EExtended strand (participates in β ladder)trans-120.1125.3178.5-67.992000109.7Y225 L249 Y263 I264 P265Y225-W251 HydrophobicContact CE1-CZ3 4.29Å; Y225-W251 HydrophobicContact CE2-CH2 4.25Å; Y225-W251 AromaticContact CZ-CH2 3.81Å; Y225-W251 AromaticContact CZ-CZ3 3.97Å; Y225-W251 VanDerWaalsContact OH-CH2 3.3Å; Y225-W251 WeakPolarHBondContact OH-CH2 3.41Å; L249-W251 PolarHBondContact O-N 2.82Å; W251-Y263 HydrophobicContact CB-CD1 4.26Å; W251-I264 WeakPolarHBondContact CA-O 3.25Å; W251-P265 HydrophobicContact CE3-CG 4.29Å; W251-P265 HydrophobicContact CH2-CG 3.88Å; W251-P265 HydrophobicContact CZ3-CG 3.73Å
252W89.5Confident83.6Confident44 Ų4476.2 Ų76.217%0.16738%0.382CS..EExtended strand (participates in β ladder)trans-110.1144.5177.7-67.1-13.3000110.2I243 E246 S247 L249 Y263 I264 V269I243-W252 HydrophobicContact CD1-CB 4.4Å; I243-W252 HydrophobicContact CD1-CE3 3.95Å; I243-W252 HydrophobicContact CG1-CE3 4.37Å; E246-W252 HydrophobicContact CG-CZ2 4.34Å; S247-W252 PolarHBondContact O-NE1 2.81Å; L249-W252 PolarHBondContact O-NE1 2.88Å; W252-Y263 CarbonylContact O-C 3.44Å; W252-Y263 VanDerWaalsContact O-CA 3.32Å; W252-Y263 WeakPolarHBondContact O-CA 3.43Å; W252-I264 HydrophobicContact CB-CG1 4.34Å; W252-I264 PolarHBondContact N-O 3.09Å; W252-I264 WeakPolarHBondContact O-CG1 3.23Å; W252-I264 PolarHBondContact O-N 2.95Å; W252-V269 HydrophobicContact CE3-CG2 4.04Å; W252-V269 HydrophobicContact CZ3-CG2 3.97Å
253R88.9Confident83.5Confident80 Ų8077.3 Ų77.330%0.30238%0.384SS..EExtended strand (participates in β ladder)trans-86.3119.5174-167.8179.3171.4-178.7-0.1108.5L244 E245 E261 Y263L244-R253 HydrophobicContact CD1-CG 4.42Å; L244-R253 PolarHBondContact N-O 3Å; E245-R253 HydrophobicContact CB-CB 4.1Å; E245-R253 PolarHBondContact N-O 3.22Å; E245-R253 PolarHBondContact O-N 2.96Å; E245-R253 IonicContact OE1-CZ 2.64Å; E245-R253 IonicContact OE1-NH1 2.81Å; E245-R253 PolarHBondContact OE1-NH1 3.16Å; R253-E261 IonicContact CZ-OE2 3.7Å; R253-E261 IonicContact NE-OE2 3.43Å; R253-E261 IonicContact NH2-OE2 2.76Å; R253-E261 PolarHBondContact NH2-OE2 2.71Å; R253-Y263 HydrophobicContact CB-CD1 4.27Å; R253-Y263 HydrophobicContact CB-CE1 4Å
254A91.8Very high83.5Confident0 Ų077 Ų770%038%0.383CS..EExtended strand (participates in β ladder)trans-127.3164.8-176.600000111.5L233 F242 I243 E261 G262 I264L233-A254 HydrophobicContact CD2-CB 4.27Å; F242-A254 CarbonylContact O-C 3.57Å; F242-A254 VanDerWaalsContact O-CA 3.24Å; F242-A254 WeakPolarHBondContact O-CA 3.45Å; I243-A254 HydrophobicContact CD1-CB 3.93Å; A254-E261 WeakPolarHBondContact O-CA 3.29Å; A254-G262 PolarHBondContact N-O 2.76Å; A254-G262 PolarHBondContact O-N 3.05Å; A254-G262 VanDerWaalsContact O-N 3.07Å; A254-I264 HydrophobicContact CB-CD1 3.47Å; A254-I264 VanDerWaalsContact CB-CD1 3.47Å; A254-I264 HydrophobicContact CB-CG1 3.75Å; A254-I264 HydrophobicContact CB-CG2 4.25Å
255R92.5Very high83.4Confident85 Ų8575.3 Ų75.332%0.32137%0.374SS..EExtended strand (participates in β ladder)trans-124.3133.4175.1-170.7-174.8-71.1159.1-1.5110Y241 F242 L244 Q260 E261Y241-R255 WeakPolarHBondContact CA-O 3.2Å; F242-R255 PolarHBondContact N-O 3.45Å; F242-R255 PolarHBondContact O-N 3.29Å; L244-R255 HydrophobicContact CD1-CB 4.1Å; L244-R255 HydrophobicContact CD2-CB 4.24Å; L244-R255 HydrophobicContact CG-CB 4.2Å; R255-Q260 CarbonylContact C-O 3.58Å; R255-Q260 VanDerWaalsContact CA-O 3.3Å; R255-Q260 WeakPolarHBondContact CA-O 3.49Å; R255-E261 HydrophobicContact CB-CG 4.27Å; R255-E261 HydrophobicContact CG-CG 4.06Å; R255-E261 IonicContact CZ-OE1 3.63Å; R255-E261 VanDerWaalsContact CZ-OE1 3.29Å; R255-E261 IonicContact NE-OE1 2.55Å; R255-E261 PolarHBondContact NE-OE1 3.46Å; R255-E261 IonicContact NH2-OE1 2.92Å; R255-E261 PolarHBondContact NH2-OE1 3.39Å
256D91.5Very high83.5Confident19 Ų1971.9 Ų71.910%0.10236%0.362CS..  trans-80.6177174.384.4-13.8000112.4L233 Y241 N258 G259 Q260L233-D256 HydrophobicContact CD1-CB 4.4Å; L233-D256 HydrophobicContact CD2-CB 4.35Å; Y241-D256 HydrophobicContact CD1-CB 4Å; Y241-D256 HydrophobicContact CE1-CB 3.83Å; D256-N258 PolarHBondContact O-N 3.24Å; D256-N258 VanDerWaalsContact OD1-C 3.28Å; D256-N258 VanDerWaalsContact OD1-CA 3.3Å; D256-N258 WeakPolarHBondContact OD1-CA 3.39Å; D256-N258 WeakPolarHBondContact OD1-CB 3.35Å; D256-N258 PolarHBondContact OD1-N 2.94Å; D256-N258 PolarHBondContact OD2-ND2 2.7Å; D256-G259 PolarHBondContact O-N 3.46Å; D256-G259 VanDerWaalsContact O-N 3.17Å; D256-G259 PolarHBondContact OD1-N 3.41Å; D256-Q260 PolarHBondContact N-O 3.4Å; D256-Q260 WeakPolarHBondContact OD1-CB 3.26Å; D256-Q260 PolarHBondContact OD1-N 2.87Å
257K85.3Confident84Confident134 Ų13471.6 Ų71.658%0.58336%0.364SS*.THydrogen-bonded Turntrans-62.8-19.2175.264.5-169.2169.3-159.60114.8D239D239-K257 VanDerWaalsContact CG-NZ 3.34Å; D239-K257 IonicContact OD1-NZ 2.83Å; D239-K257 PolarHBondContact OD1-NZ 3.38Å; D239-K257 IonicContact OD2-NZ 3.19Å; D239-K257 PolarHBondContact OD2-NZ 2.95Å
258N84.9Confident84.7Confident131 Ų13172.8 Ų72.870%0.70136%0.361SS*.THydrogen-bonded Turntrans-93.7-1.2179.1-51.7-58.3000112.4D256D256-N258 PolarHBondContact O-N 3.24Å; D256-N258 VanDerWaalsContact OD1-C 3.28Å; D256-N258 VanDerWaalsContact OD1-CA 3.3Å; D256-N258 WeakPolarHBondContact OD1-CA 3.39Å; D256-N258 WeakPolarHBondContact OD1-CB 3.35Å; D256-N258 PolarHBondContact OD1-N 2.94Å; D256-N258 PolarHBondContact OD2-ND2 2.7Å
259G83.7Confident85.9Confident44 Ų4464.9 Ų64.945%0.45432%0.319SS..SBendtrans84.76.3-177.500000114.6D256D256-G259 PolarHBondContact O-N 3.46Å; D256-G259 VanDerWaalsContact O-N 3.17Å; D256-G259 PolarHBondContact OD1-N 3.41Å
260Q88.5Confident86.2Confident124 Ų12461.1 Ų61.158%0.57930%0.3SS*.  trans-73.3131.2174.3-169.217136.100110.1L233 R255 D256L233-Q260 HydrophobicContact CD1-CB 4.03Å; L233-Q260 HydrophobicContact CD1-CG 3.82Å; R255-Q260 CarbonylContact C-O 3.58Å; R255-Q260 VanDerWaalsContact CA-O 3.3Å; R255-Q260 WeakPolarHBondContact CA-O 3.49Å; D256-Q260 PolarHBondContact N-O 3.4Å; D256-Q260 WeakPolarHBondContact OD1-CB 3.26Å; D256-Q260 PolarHBondContact OD1-N 2.87Å
261E92.6Very high86.1Confident75 Ų7562.4 Ų62.435%0.3530%0.299SS..EExtended strand (participates in β ladder)trans-108.3147.4179.6-57.9-173.7175.100111.2L244 R253 A254 R255L244-E261 HydrophobicContact CD1-CB 4.33Å; L244-E261 HydrophobicContact CD1-CG 3.75Å; L244-E261 WeakPolarHBondContact CD1-OE1 3.47Å; R253-E261 IonicContact CZ-OE2 3.7Å; R253-E261 IonicContact NE-OE2 3.43Å; R253-E261 IonicContact NH2-OE2 2.76Å; R253-E261 PolarHBondContact NH2-OE2 2.71Å; A254-E261 WeakPolarHBondContact O-CA 3.29Å; R255-E261 HydrophobicContact CB-CG 4.27Å; R255-E261 HydrophobicContact CG-CG 4.06Å; R255-E261 IonicContact CZ-OE1 3.63Å; R255-E261 VanDerWaalsContact CZ-OE1 3.29Å; R255-E261 IonicContact NE-OE1 2.55Å; R255-E261 PolarHBondContact NE-OE1 3.46Å; R255-E261 IonicContact NH2-OE1 2.92Å; R255-E261 PolarHBondContact NH2-OE1 3.39Å
262G91.1Very high85.1Confident8 Ų859.7 Ų59.78%0.08230%0.298CS..EExtended strand (participates in β ladder)trans178.3-175.8171.300000111.6N231 A254N231-G262 CarbonylContact O-C 3.43Å; N231-G262 VanDerWaalsContact O-CA 3.29Å; N231-G262 WeakPolarHBondContact O-CA 3.43Å; A254-G262 PolarHBondContact N-O 2.76Å; A254-G262 PolarHBondContact O-N 3.05Å; A254-G262 VanDerWaalsContact O-N 3.07Å
263Y90.3Very high83.3Confident93 Ų9365.9 Ų65.937%0.36533%0.329SS..EExtended strand (participates in β ladder)trans-88.6137.1179.5-70-81.6000111.6N231 D232 L233 W251 W252 R253N231-Y263 HydrophobicContact CB-CD2 4.11Å; N231-Y263 WeakPolarHBondContact O-CD2 3.25Å; N231-Y263 PolarHBondContact O-N 3.44Å; D232-Y263 CarbonylContact C-O 3.59Å; D232-Y263 WeakPolarHBondContact CA-O 3.48Å; L233-Y263 PolarHBondContact N-O 3.46Å; W251-Y263 HydrophobicContact CB-CD1 4.26Å; W252-Y263 CarbonylContact O-C 3.44Å; W252-Y263 VanDerWaalsContact O-CA 3.32Å; W252-Y263 WeakPolarHBondContact O-CA 3.43Å; R253-Y263 HydrophobicContact CB-CD1 4.27Å; R253-Y263 HydrophobicContact CB-CE1 4Å
264I90.1Very high81.5Confident0 Ų069.8 Ų69.80%036%0.356CS..EExtended strand (participates in β ladder)trans-125.7147.9175.762.3168000110L233 L235 I243 W251 W252 A254 S266 V269L233-I264 HydrophobicContact CB-CG2 3.71Å; L233-I264 HydrophobicContact CD2-CG2 4.09Å; L233-I264 HydrophobicContact CG-CG2 4.24Å; L235-I264 HydrophobicContact CD1-CB 4.2Å; L235-I264 HydrophobicContact CD2-CB 4.09Å; L235-I264 HydrophobicContact CD2-CD1 4.1Å; L235-I264 HydrophobicContact CD2-CG2 3.65Å; L235-I264 HydrophobicContact CG-CB 4.29Å; L235-I264 HydrophobicContact CG-CG2 4.05Å; I243-I264 HydrophobicContact CD1-CD1 4.06Å; W251-I264 WeakPolarHBondContact CA-O 3.25Å; W252-I264 HydrophobicContact CB-CG1 4.34Å; W252-I264 PolarHBondContact N-O 3.09Å; W252-I264 WeakPolarHBondContact O-CG1 3.23Å; W252-I264 PolarHBondContact O-N 2.95Å; A254-I264 HydrophobicContact CB-CD1 3.47Å; A254-I264 VanDerWaalsContact CB-CD1 3.47Å; A254-I264 HydrophobicContact CB-CG1 3.75Å; A254-I264 HydrophobicContact CB-CG2 4.25Å; I264-S266 PolarHBondContact O-N 3.05Å; I264-V269 HydrophobicContact CD1-CG1 3.71Å; I264-V269 HydrophobicContact CD1-CG2 4.12Å
265P85.4Confident79.9Confident8 Ų871.2 Ų71.25%0.05237%0.366CS..EExtended strand (participates in β ladder)trans-67.9126.5173-14.527.9000110.4Y225 P250 W251 N267 Y268Y225-P265 HydrophobicContact CD1-CG 4.46Å; Y225-P265 HydrophobicContact CD2-CG 3.95Å; Y225-P265 HydrophobicContact CE1-CG 4.48Å; Y225-P265 HydrophobicContact CE2-CG 3.99Å; Y225-P265 HydrophobicContact CG-CG 4.22Å; P250-P265 WeakPolarHBondContact O-CA 3.14Å; W251-P265 HydrophobicContact CE3-CG 4.29Å; W251-P265 HydrophobicContact CH2-CG 3.88Å; W251-P265 HydrophobicContact CZ3-CG 3.73Å; P265-N267 WeakPolarHBondContact CB-OD1 3.38Å; P265-N267 PolarHBondContact O-N 3.35Å; P265-Y268 HydrophobicContact CB-CD2 3.64Å; P265-Y268 HydrophobicContact CB-CE2 4.27Å; P265-Y268 HydrophobicContact CB-CG 4.06Å; P265-Y268 HydrophobicContact CG-CD2 4.09Å; P265-Y268 HydrophobicContact CG-CG 4.19Å; P265-Y268 WeakPolarHBondContact O-CB 3.48Å; P265-Y268 PolarHBondContact O-N 2.55Å
266S82.6Confident78.8Confident28 Ų2869 Ų6920%0.19636%0.36CS..G310 helixtrans-64.4-29.1-176.960.90000113.3P250 I264 Y268 V269P250-S266 PolarHBondContact O-N 3.22Å; P250-S266 PolarHBondContact O-OG 2.93Å; I264-S266 PolarHBondContact O-N 3.05Å; S266-Y268 PolarHBondContact O-N 2.93Å; S266-V269 WeakPolarHBondContact O-CG2 3.29Å
267N79.7Confident77.5Confident108 Ų10872 Ų7258%0.57837%0.373SS*.G310 helixtrans-77-1.6176.667.8-49.6000114.2P265P265-N267 WeakPolarHBondContact CB-OD1 3.38Å; P265-N267 PolarHBondContact O-N 3.35Å
268Y81Confident76.2Confident78 Ų7873.1 Ų73.131%0.30638%0.383SS..G310 helixtrans-99.6-1.3178.1-82.2-124.5000112.6A221 L222 Y223 Y225 L235 P265 S266A221-Y268 WeakPolarHBondContact CA-O 3.46Å; L222-Y268 PolarHBondContact N-O 3.45Å; Y223-Y268 HydrophobicContact CD2-CD1 4.25Å; Y223-Y268 HydrophobicContact CD2-CG 4.3Å; Y223-Y268 HydrophobicContact CG-CD1 4.47Å; Y225-Y268 HydrophobicContact CD2-CE1 4.38Å; L235-Y268 HydrophobicContact CD1-CG 4.45Å; P265-Y268 HydrophobicContact CB-CD2 3.64Å; P265-Y268 HydrophobicContact CB-CE2 4.27Å; P265-Y268 HydrophobicContact CB-CG 4.06Å; P265-Y268 HydrophobicContact CG-CD2 4.09Å; P265-Y268 HydrophobicContact CG-CG 4.19Å; P265-Y268 WeakPolarHBondContact O-CB 3.48Å; P265-Y268 PolarHBondContact O-N 2.55Å; S266-Y268 PolarHBondContact O-N 2.93Å
269V80.9Confident75.5Confident13 Ų1372.8 Ų72.88%0.07937%0.372CS..EExtended strand (participates in β ladder)trans-131.4153.9-177-64.10000111.6V219 V220 A221 L235 W252 I264 S266V219-V269 HydrophobicContact CB-CB 4.08Å; V219-V269 HydrophobicContact CB-CG2 4.36Å; V219-V269 HydrophobicContact CG2-CB 3.91Å; V219-V269 HydrophobicContact CG2-CG1 4.17Å; V219-V269 HydrophobicContact CG2-CG2 4.11Å; V220-V269 CarbonylContact O-C 3.59Å; V220-V269 VanDerWaalsContact O-CA 3.25Å; V220-V269 WeakPolarHBondContact O-CA 3.37Å; A221-V269 HydrophobicContact CB-CG1 4.47Å; L235-V269 HydrophobicContact CD1-CG1 3.87Å; L235-V269 HydrophobicContact CD2-CG1 4.11Å; W252-V269 HydrophobicContact CE3-CG2 4.04Å; W252-V269 HydrophobicContact CZ3-CG2 3.97Å; I264-V269 HydrophobicContact CD1-CG1 3.71Å; I264-V269 HydrophobicContact CD1-CG2 4.12Å; S266-V269 WeakPolarHBondContact O-CG2 3.29Å
270T77.8Confident74.9Confident31 Ų3180.1 Ų80.119%0.1940%0.395CS..EExtended strand (participates in β ladder)trans-130.5157.4175.7-170.70000110.7V219 V220 L222V219-T270 CarbonylContact C-O 3.59Å; V219-T270 WeakPolarHBondContact CA-O 3.3Å; V219-T270 WeakPolarHBondContact CB-O 3.38Å; V220-T270 HydrophobicContact CB-CG2 4.4Å; V220-T270 PolarHBondContact N-O 2.92Å; V220-T270 PolarHBondContact O-N 2.64Å; L222-T270 HydrophobicContact CD2-CG2 3.65Å; L222-T270 HydrophobicContact CG-CG2 4.15Å
271E77.3Confident74.4Confident108 Ų10878.4 Ų78.451%0.50538%0.383SS..EExtended strand (participates in β ladder)trans-64137.7175.7-67-178.7-173.900110.8K217 E273K217-E271 WeakPolarHBondContact CE-OE1 3.45Å; K217-E271 IonicContact NZ-OE1 3.61Å; K217-E271 PolarHBondContact NZ-OE1 2.76Å; E271-E273 PolarHBondContact O-N 3.01Å
272A61.2Low73.8Confident42 Ų4275.9 Ų75.935%0.34737%0.37SS..SBendtrans-71.2-8.2-172.900000114.2K218 V220K218-A272 HydrophobicContact CB-CB 4.22Å; K218-A272 HydrophobicContact CD-CB 4.2Å; K218-A272 HydrophobicContact CG-CB 4Å; K218-A272 WeakPolarHBondContact O-CB 3.27Å; K218-A272 PolarHBondContact O-N 3.47Å; K218-A272 VanDerWaalsContact O-N 3.14Å; V220-A272 HydrophobicContact CG2-CB 3.94Å
273E52.3Low73.3Confident174 Ų17477.3 Ų77.381%0.81338%0.379SS*.SBendtrans-98.2110.8177.2-65.9-174.6171.900110.1E271 S275E271-E273 PolarHBondContact O-N 3.01Å; E273-S275 PolarHBondContact O-N 3.16Å
274D50.9Low72.6Confident163 Ų16377.2 Ų77.287%0.87238%0.38SS*.  trans58.737.8162.2-66-31.1000118.5I276D274-I276 PolarHBondContact O-N 3.3Å; D274-I276 VanDerWaalsContact O-N 3.1Å
275S59.2Low71.9Confident29 Ų2984.9 Ų84.920%0.20342%0.416CS..  trans-74.8105166.793.20000110.2E273 E277 M278E273-S275 PolarHBondContact O-N 3.16Å; S275-E277 PolarHBondContact O-N 3.31Å; S275-M278 WeakPolarHBondContact O-CB 3.16Å; S275-M278 PolarHBondContact O-N 3.48Å
276I67.9Low71.8Confident40 Ų4086.7 Ų86.721%0.20542%0.424CS..G310 helixtrans-53.5-18.7172.5-165.6170.5000112.6D274 M278 Y279 W281 Y282D274-I276 PolarHBondContact O-N 3.3Å; D274-I276 VanDerWaalsContact O-N 3.1Å; I276-M278 PolarHBondContact O-N 3.37Å; I276-Y279 HydrophobicContact CG1-CD2 4.46Å; I276-Y279 PolarHBondContact O-N 3.18Å; I276-W281 HydrophobicContact CD1-CH2 3.95Å; I276-W281 HydrophobicContact CD1-CZ3 3.94Å; I276-W281 HydrophobicContact CG1-CH2 3.73Å; I276-W281 HydrophobicContact CG1-CZ3 3.91Å; I276-Y282 HydrophobicContact CD1-CD2 3.9Å; I276-Y282 HydrophobicContact CD1-CE2 4.22Å; I276-Y282 HydrophobicContact CD1-CG 4.45Å; I276-Y282 HydrophobicContact CG1-CD2 3.96Å; I276-Y282 HydrophobicContact CG1-CE2 4.48Å; I276-Y282 HydrophobicContact CG1-CG 3.99Å; I276-Y282 HydrophobicContact CG2-CD1 4.1Å; I276-Y282 HydrophobicContact CG2-CD2 4.27Å; I276-Y282 HydrophobicContact CG2-CE1 3.85Å; I276-Y282 HydrophobicContact CG2-CE2 4.07Å; I276-Y282 HydrophobicContact CG2-CG 4.28Å; I276-Y282 WeakPolarHBondContact O-CB 3.33Å
277E65.4Low71.9Confident81 Ų8188.8 Ų88.838%0.37944%0.436SS..G310 helixtrans-62.7-15.9175.6-55.4-166.4175.300114S275 Y279 Y282 K284S275-E277 PolarHBondContact O-N 3.31Å; E277-Y279 VanDerWaalsContact C-N 3.34Å; E277-Y282 HydrophobicContact CG-CD1 4.39Å; E277-Y282 HydrophobicContact CG-CE1 3.95Å; E277-K284 WeakPolarHBondContact OE1-CD 3.23Å; E277-K284 WeakPolarHBondContact OE1-CE 3.48Å; E277-K284 IonicContact OE1-NZ 2.83Å; E277-K284 PolarHBondContact OE1-NZ 2.92Å
278M57.7Low72.1Confident158 Ų15890.6 Ų90.678%0.77844%0.435SS*.G310 helixtrans-73-24.1175.5-172178.3-178.500113.2S275 I276S275-M278 WeakPolarHBondContact O-CB 3.16Å; S275-M278 PolarHBondContact O-N 3.48Å; I276-M278 PolarHBondContact O-N 3.37Å
279Y70.1Confident72.2Confident123 Ų12390.9 Ų90.948%0.48245%0.448SS..SBendtrans-87.2130-172.6-64.4-80.8000112.5I276 E277 W281 Y282I276-Y279 HydrophobicContact CG1-CD2 4.46Å; I276-Y279 PolarHBondContact O-N 3.18Å; E277-Y279 VanDerWaalsContact C-N 3.34Å; Y279-W281 AromaticContact CD1-CE2 3.84Å; Y279-W281 AromaticContact CD1-CZ2 3.81Å; Y279-W281 HydrophobicContact CD1-CZ2 3.81Å; Y279-W281 AromaticContact CD1-NE1 3.53Å; Y279-W281 HydrophobicContact CD2-CH2 4.05Å; Y279-W281 AromaticContact CD2-CZ2 3.62Å; Y279-W281 HydrophobicContact CD2-CZ2 3.62Å; Y279-W281 HydrophobicContact CE1-CZ2 4.41Å; Y279-W281 HydrophobicContact CE2-CZ2 4.26Å; Y279-W281 HydrophobicContact CG-CD2 4.46Å; Y279-W281 AromaticContact CG-CE2 3.55Å; Y279-W281 HydrophobicContact CG-CH2 4.15Å; Y279-W281 AromaticContact CG-CZ2 3.36Å; Y279-W281 HydrophobicContact CG-CZ2 3.36Å; Y279-W281 AromaticContact CG-NE1 3.69Å; Y279-W281 PolarHBondContact O-N 3.33Å; Y279-W281 VanDerWaalsContact O-N 3.12Å; Y279-Y282 PolarHBondContact O-N 3.15Å
280E70.4Confident72.4Confident198 Ų19894.9 Ų94.993%0.92547%0.466SS*.THydrogen-bonded Turntrans-59.4-26.1-179.7-62.9-173.3156.700113.8Y282E280-Y282 VanDerWaalsContact C-N 3.28Å; E280-Y282 PolarHBondContact O-N 2.91Å
281W79.1Confident72.7Confident89 Ų8993.4 Ų93.434%0.33746%0.457SS..THydrogen-bonded Turntrans-78.3-9.3177.251.6-106.5000113.5I276 Y279 F304 V306I276-W281 HydrophobicContact CD1-CH2 3.95Å; I276-W281 HydrophobicContact CD1-CZ3 3.94Å; I276-W281 HydrophobicContact CG1-CH2 3.73Å; I276-W281 HydrophobicContact CG1-CZ3 3.91Å; Y279-W281 AromaticContact CD1-CE2 3.84Å; Y279-W281 AromaticContact CD1-CZ2 3.81Å; Y279-W281 HydrophobicContact CD1-CZ2 3.81Å; Y279-W281 AromaticContact CD1-NE1 3.53Å; Y279-W281 HydrophobicContact CD2-CH2 4.05Å; Y279-W281 AromaticContact CD2-CZ2 3.62Å; Y279-W281 HydrophobicContact CD2-CZ2 3.62Å; Y279-W281 HydrophobicContact CE1-CZ2 4.41Å; Y279-W281 HydrophobicContact CE2-CZ2 4.26Å; Y279-W281 HydrophobicContact CG-CD2 4.46Å; Y279-W281 AromaticContact CG-CE2 3.55Å; Y279-W281 HydrophobicContact CG-CH2 4.15Å; Y279-W281 AromaticContact CG-CZ2 3.36Å; Y279-W281 HydrophobicContact CG-CZ2 3.36Å; Y279-W281 AromaticContact CG-NE1 3.69Å; Y279-W281 PolarHBondContact O-N 3.33Å; Y279-W281 VanDerWaalsContact O-N 3.12Å; W281-F304 HydrophobicContact CB-CE2 3.94Å; W281-F304 HydrophobicContact CB-CZ 4.36Å; W281-F304 HydrophobicContact CD2-CE2 4.42Å; W281-F304 HydrophobicContact CG-CE2 4.08Å; W281-F304 HydrophobicContact CG-CZ 4.41Å; W281-V306 HydrophobicContact CD2-CG2 4.42Å; W281-V306 HydrophobicContact CE3-CB 3.62Å; W281-V306 HydrophobicContact CE3-CG2 3.35Å; W281-V306 HydrophobicContact CZ3-CB 3.67Å; W281-V306 HydrophobicContact CZ3-CG1 4.14Å; W281-V306 HydrophobicContact CZ3-CG2 3.52Å; W281-V306 PolarHBondContact O-N 3.47Å
282Y80.3Confident73.2Confident22 Ų2290.6 Ų90.69%0.08644%0.444CS..EExtended strand (participates in β ladder)trans-97132.6178.8179.6-103000111.4I276 E277 Y279 E280 K284 V306 D308 Y315I276-Y282 HydrophobicContact CD1-CD2 3.9Å; I276-Y282 HydrophobicContact CD1-CE2 4.22Å; I276-Y282 HydrophobicContact CD1-CG 4.45Å; I276-Y282 HydrophobicContact CG1-CD2 3.96Å; I276-Y282 HydrophobicContact CG1-CE2 4.48Å; I276-Y282 HydrophobicContact CG1-CG 3.99Å; I276-Y282 HydrophobicContact CG2-CD1 4.1Å; I276-Y282 HydrophobicContact CG2-CD2 4.27Å; I276-Y282 HydrophobicContact CG2-CE1 3.85Å; I276-Y282 HydrophobicContact CG2-CE2 4.07Å; I276-Y282 HydrophobicContact CG2-CG 4.28Å; I276-Y282 WeakPolarHBondContact O-CB 3.33Å; E277-Y282 HydrophobicContact CG-CD1 4.39Å; E277-Y282 HydrophobicContact CG-CE1 3.95Å; Y279-Y282 PolarHBondContact O-N 3.15Å; E280-Y282 VanDerWaalsContact C-N 3.28Å; E280-Y282 PolarHBondContact O-N 2.91Å; Y282-K284 HydrophobicContact CE1-CB 3.89Å; Y282-K284 HydrophobicContact CE1-CG 4.49Å; Y282-V306 CarbonylContact C-O 3.52Å; Y282-V306 WeakPolarHBondContact CA-O 3.34Å; Y282-V306 HydrophobicContact CD2-CB 4.18Å; Y282-V306 HydrophobicContact CD2-CG1 4.03Å; Y282-D308 PolarHBondContact OH-OD1 3.42Å; Y282-Y315 AromaticContact CE2-CD1 3.82Å; Y282-Y315 HydrophobicContact CE2-CD1 3.82Å; Y282-Y315 AromaticContact CE2-CE1 3.86Å; Y282-Y315 HydrophobicContact CE2-CE1 3.86Å
283S81.1Confident74.4Confident38 Ų3895 Ų9527%0.26646%0.457SS..EExtended strand (participates in β ladder)trans-137.397.2178.9-67.30000110.8H285 M286 V306 R307S283-H285 PolarHBondContact O-N 3.38Å; S283-M286 WeakPolarHBondContact O-CB 3.32Å; S283-M286 PolarHBondContact O-N 3.45Å; S283-V306 PolarHBondContact N-O 2.81Å; S283-R307 WeakPolarHBondContact O-CA 3.41Å; S283-R307 WeakPolarHBondContact O-CB 3.37Å
284K75.6Confident76Confident90 Ų9090 Ų9039%0.39144%0.436SS..THydrogen-bonded Turntrans-51.9-51.2-175.1-167.7173.1-169.7164.30114E277 Y282 D308E277-K284 WeakPolarHBondContact OE1-CD 3.23Å; E277-K284 WeakPolarHBondContact OE1-CE 3.48Å; E277-K284 IonicContact OE1-NZ 2.83Å; E277-K284 PolarHBondContact OE1-NZ 2.92Å; Y282-K284 HydrophobicContact CE1-CB 3.89Å; Y282-K284 HydrophobicContact CE1-CG 4.49Å; K284-D308 WeakPolarHBondContact CG-OD2 3.32Å; K284-D308 WeakPolarHBondContact O-CB 3.39Å
285H75.3Confident77.7Confident162 Ų16282.6 Ų82.675%0.7540%0.396SS*.THydrogen-bonded Turntrans-96.115-174.1-58.9-60.1000114.4S283 T287S283-H285 PolarHBondContact O-N 3.38Å; H285-T287 PolarHBondContact O-N 2.98Å
286M82.9Confident78.9Confident45 Ų4586.9 Ų86.922%0.22241%0.411CS..  trans-77.9122.3-177.6-171.869.873.300111.4S283 Q290 A291 L294 I305 R307S283-M286 WeakPolarHBondContact O-CB 3.32Å; S283-M286 PolarHBondContact O-N 3.45Å; M286-Q290 HydrophobicContact CG-CB 4.39Å; M286-Q290 HydrophobicContact SD-CB 3.39Å; M286-Q290 WeakPolarHBondContact SD-CB 3.35Å; M286-A291 HydrophobicContact CG-CB 4.13Å; M286-L294 HydrophobicContact CE-CD2 4.14Å; M286-I305 HydrophobicContact CG-CD1 3.87Å; M286-R307 HydrophobicContact CB-CB 4.03Å; M286-R307 WeakPolarHBondContact O-CD 3.46Å
287T84.4Confident79.7Confident72 Ų7292.3 Ų92.344%0.44244%0.436SS..  trans-78.3162.7174.266.60000111.9H285 S289 Q290 A291H285-T287 PolarHBondContact O-N 2.98Å; T287-S289 VanDerWaalsContact C-N 3.3Å; T287-S289 PolarHBondContact O-N 3.41Å; T287-Q290 PolarHBondContact O-N 3.41Å; T287-Q290 WeakPolarHBondContact OG1-CB 3.36Å; T287-Q290 VanDerWaalsContact OG1-CD 3.23Å; T287-Q290 VanDerWaalsContact OG1-CG 3.25Å; T287-Q290 WeakPolarHBondContact OG1-CG 3.48Å; T287-Q290 PolarHBondContact OG1-N 3.25Å; T287-Q290 PolarHBondContact OG1-OE1 3.36Å; T287-A291 WeakPolarHBondContact O-CB 3.41Å; T287-A291 PolarHBondContact O-N 3.42Å
288R82.6Confident80.6Confident146 Ų14693.8 Ų93.855%0.55144%0.442SS*.Hα-helixtrans-54.9-45.1175-178-178170.91680.7112.4A291 E292R288-A291 WeakPolarHBondContact O-CB 3.45Å; R288-A291 PolarHBondContact O-N 3.18Å; R288-E292 IonicContact CZ-OE1 2.79Å; R288-E292 IonicContact NE-OE1 3.71Å; R288-E292 PolarHBondContact NE-OE1 2.88Å; R288-E292 IonicContact NH2-OE1 3.99Å; R288-E292 PolarHBondContact NH2-OE1 3.45Å; R288-E292 WeakPolarHBondContact O-CG 3.21Å; R288-E292 PolarHBondContact O-N 2.97Å
289S83.6Confident81.6Confident84 Ų8487.5 Ų87.559%0.58742%0.418SS*.Hα-helixtrans-69-40.1-177-58.90000112.1T287 E292 Q293T287-S289 VanDerWaalsContact C-N 3.3Å; T287-S289 PolarHBondContact O-N 3.41Å; S289-E292 PolarHBondContact O-N 2.79Å; S289-Q293 PolarHBondContact O-N 2.97Å
290Q84.6Confident82.1Confident98 Ų9888 Ų8846%0.45842%0.423SS..Hα-helixtrans-65.8-40.6175.4-69.6164.9-42.500111.6M286 T287 E292 Q293 L294M286-Q290 HydrophobicContact CG-CB 4.39Å; M286-Q290 HydrophobicContact SD-CB 3.39Å; M286-Q290 WeakPolarHBondContact SD-CB 3.35Å; T287-Q290 PolarHBondContact O-N 3.41Å; T287-Q290 WeakPolarHBondContact OG1-CB 3.36Å; T287-Q290 VanDerWaalsContact OG1-CD 3.23Å; T287-Q290 VanDerWaalsContact OG1-CG 3.25Å; T287-Q290 WeakPolarHBondContact OG1-CG 3.48Å; T287-Q290 PolarHBondContact OG1-N 3.25Å; T287-Q290 PolarHBondContact OG1-OE1 3.36Å; Q290-E292 VanDerWaalsContact C-N 3.32Å; Q290-E292 PolarHBondContact O-N 3.34Å; Q290-Q293 PolarHBondContact O-N 3.14Å; Q290-L294 WeakPolarHBondContact O-CB 3.39Å; Q290-L294 PolarHBondContact O-N 3.16Å
291A85.3Confident82.5Confident0 Ų085.4 Ų85.40%041%0.411CS..Hα-helixtrans-57.6-45173.200000112M286 T287 R288 L295 I305M286-A291 HydrophobicContact CG-CB 4.13Å; T287-A291 WeakPolarHBondContact O-CB 3.41Å; T287-A291 PolarHBondContact O-N 3.42Å; R288-A291 WeakPolarHBondContact O-CB 3.45Å; R288-A291 PolarHBondContact O-N 3.18Å; A291-L295 WeakPolarHBondContact O-CB 3.34Å; A291-L295 WeakPolarHBondContact O-CG 3.27Å; A291-L295 PolarHBondContact O-N 3.43Å; A291-I305 HydrophobicContact CB-CD1 3.43Å; A291-I305 VanDerWaalsContact CB-CD1 3.43Å; A291-I305 HydrophobicContact CB-CG1 4.23Å
292E86.8Confident82.4Confident48 Ų4883.2 Ų83.222%0.22442%0.416CS..Hα-helixtrans-65.4-38.6178.4-72.9175.6-172.900112.2R288 S289 Q290 K296 I331 H333R288-E292 IonicContact CZ-OE1 2.79Å; R288-E292 IonicContact NE-OE1 3.71Å; R288-E292 PolarHBondContact NE-OE1 2.88Å; R288-E292 IonicContact NH2-OE1 3.99Å; R288-E292 PolarHBondContact NH2-OE1 3.45Å; R288-E292 WeakPolarHBondContact O-CG 3.21Å; R288-E292 PolarHBondContact O-N 2.97Å; S289-E292 PolarHBondContact O-N 2.79Å; Q290-E292 VanDerWaalsContact C-N 3.32Å; Q290-E292 PolarHBondContact O-N 3.34Å; E292-K296 VanDerWaalsContact O-CB 3.3Å; E292-K296 WeakPolarHBondContact O-CB 3.33Å; E292-K296 WeakPolarHBondContact O-CG 3.29Å; E292-K296 PolarHBondContact O-N 2.89Å; E292-K296 VanDerWaalsContact O-N 3.14Å; E292-I331 HydrophobicContact CB-CD1 3.86Å; E292-I331 HydrophobicContact CG-CB 4.13Å; E292-I331 HydrophobicContact CG-CD1 4.07Å; E292-I331 HydrophobicContact CG-CG2 4.07Å; E292-I331 WeakPolarHBondContact O-CD1 3.41Å; E292-H333 WeakPolarHBondContact CG-NE2 3.36Å; E292-H333 IonicContact OE1-CD2 2.86Å; E292-H333 IonicContact OE1-CE1 3.29Å; E292-H333 IonicContact OE1-NE2 2.69Å; E292-H333 PolarHBondContact OE1-NE2 2.89Å
293Q86.3Confident82.6Confident136 Ų13683 Ų8364%0.63642%0.42SS*.Hα-helixtrans-66.9-46.5177.2-175.5177.2-16.200111.8S289 Q290 K296 Q297S289-Q293 PolarHBondContact O-N 2.97Å; Q290-Q293 PolarHBondContact O-N 3.14Å; Q293-K296 PolarHBondContact O-N 3.39Å; Q293-Q297 WeakPolarHBondContact O-CB 3.43Å; Q293-Q297 PolarHBondContact O-N 3.22Å
294L86.9Confident82.9Confident69 Ų6986 Ų8636%0.36143%0.428SS..Hα-helixtrans-63.6-48.2-178.7-173.869.3000111.7M286 Q290 K296 Q297 E298M286-L294 HydrophobicContact CE-CD2 4.14Å; Q290-L294 WeakPolarHBondContact O-CB 3.39Å; Q290-L294 PolarHBondContact O-N 3.16Å; L294-K296 VanDerWaalsContact C-N 3.34Å; L294-K296 PolarHBondContact O-N 3.5Å; L294-Q297 WeakPolarHBondContact O-CB 3.39Å; L294-Q297 PolarHBondContact O-N 2.9Å; L294-Q297 VanDerWaalsContact O-N 3.17Å; L294-E298 PolarHBondContact O-N 2.96Å
295L86.4Confident83.5Confident7 Ų782.4 Ų82.44%0.03741%0.413CS..Hα-helixtrans-66-35.2179.8-74.4173.2000112.5A291 G299 I305 S318 F320 I331A291-L295 WeakPolarHBondContact O-CB 3.34Å; A291-L295 WeakPolarHBondContact O-CG 3.27Å; A291-L295 PolarHBondContact O-N 3.43Å; L295-G299 PolarHBondContact O-N 3.22Å; L295-G299 VanDerWaalsContact O-N 3.08Å; L295-I305 HydrophobicContact CD1-CG1 4.32Å; L295-I305 HydrophobicContact CD2-CG2 4.26Å; L295-S318 WeakPolarHBondContact CD1-O 3.46Å; L295-F320 HydrophobicContact CB-CB 4.27Å; L295-I331 HydrophobicContact CB-CD1 4.25Å; L295-I331 HydrophobicContact CB-CG1 3.98Å; L295-I331 HydrophobicContact CD1-CG1 4.24Å; L295-I331 HydrophobicContact CD1-CG2 4.08Å
296K83.8Confident84.1Confident119 Ų11975.2 Ų75.252%0.51738%0.381SS..Hα-helixtrans-67.4-38171.9-87.1168.2-177.7-1710112.6E292 Q293 L294 G299 F320 I331E292-K296 VanDerWaalsContact O-CB 3.3Å; E292-K296 WeakPolarHBondContact O-CB 3.33Å; E292-K296 WeakPolarHBondContact O-CG 3.29Å; E292-K296 PolarHBondContact O-N 2.89Å; E292-K296 VanDerWaalsContact O-N 3.14Å; Q293-K296 PolarHBondContact O-N 3.39Å; L294-K296 VanDerWaalsContact C-N 3.34Å; L294-K296 PolarHBondContact O-N 3.5Å; K296-G299 PolarHBondContact O-N 3.37Å; K296-F320 HydrophobicContact CG-CE2 4.17Å; K296-I331 HydrophobicContact CD-CD1 3.92Å; K296-I331 HydrophobicContact CG-CD1 3.59Å
297Q85.9Confident84.3Confident154 Ų15473.7 Ų73.772%0.7237%0.372SS*.Hα-helixtrans-66.4-40.8178.3-175.81796.600111.6Q293 L294Q293-Q297 WeakPolarHBondContact O-CB 3.43Å; Q293-Q297 PolarHBondContact O-N 3.22Å; L294-Q297 WeakPolarHBondContact O-CB 3.39Å; L294-Q297 PolarHBondContact O-N 2.9Å; L294-Q297 VanDerWaalsContact O-N 3.17Å
298E84.3Confident84.2Confident111 Ų11173 Ų7352%0.51937%0.366SS..Hα-helixtrans-67-38.5173.9-76.6-132.2159.300112.5L294 K300L294-E298 PolarHBondContact O-N 2.96Å; E298-K300 PolarHBondContact O-N 2.86Å; E298-K300 IonicContact OE2-NZ 3.65Å
299G78.8Confident84Confident26 Ų2666.9 Ų66.927%0.26835%0.346SS..  trans6510.8174.300000115.5L295 K296 K322L295-G299 PolarHBondContact O-N 3.22Å; L295-G299 VanDerWaalsContact O-N 3.08Å; K296-G299 PolarHBondContact O-N 3.37Å; G299-K322 PolarHBondContact O-NZ 3.12Å
300K79.6Confident83.3Confident134 Ų13468.8 Ų68.858%0.58336%0.359SS*.  trans-84.2121.5179.6-69.6178.4-174.2161.30111E298 G302 G303 F320E298-K300 PolarHBondContact O-N 2.86Å; E298-K300 IonicContact OE2-NZ 3.65Å; K300-G302 PolarHBondContact O-N 3.31Å; K300-G303 PolarHBondContact O-N 3.48Å; K300-F320 WeakPolarHBondContact O-CD1 3.31Å
301E79.9Confident82.4Confident144 Ų14470.9 Ų70.967%0.67337%0.367SS*.THydrogen-bonded Turntrans-59.8132.9173.1-173.6172-173.900110.9G303 K322E301-G303 PolarHBondContact O-N 3.01Å; E301-K322 HydrophobicContact CG-CB 4.41Å
302G75.6Confident81.3Confident43 Ų4376 Ų7644%0.44341%0.409SS..THydrogen-bonded Turntrans78.8-2.2-175.700000114.4K300 F304 F320K300-G302 PolarHBondContact O-N 3.31Å; G302-F304 PolarHBondContact O-N 3.4Å; G302-F320 PolarHBondContact N-O 3.13Å
303G84.2Confident80.3Confident16 Ų1677.4 Ų77.417%0.16544%0.436CS..  trans-58.1131.8171.800000110.6K300 E301 V319 F320K300-G303 PolarHBondContact O-N 3.48Å; E301-G303 PolarHBondContact O-N 3.01Å; G303-V319 CarbonylContact O-C 3.46Å; G303-V319 WeakPolarHBondContact O-CA 3.4Å; G303-F320 PolarHBondContact O-N 3.13Å
304F89.1Confident79.8Confident101 Ų10174.8 Ų74.844%0.44342%0.423SS..EExtended strand (participates in β ladder)trans-139.5155.5-17773.8-85.4000112.3W281 G302 V306 V317 S318 V319W281-F304 HydrophobicContact CB-CE2 3.94Å; W281-F304 HydrophobicContact CB-CZ 4.36Å; W281-F304 HydrophobicContact CD2-CE2 4.42Å; W281-F304 HydrophobicContact CG-CE2 4.08Å; W281-F304 HydrophobicContact CG-CZ 4.41Å; G302-F304 PolarHBondContact O-N 3.4Å; F304-V306 HydrophobicContact CD2-CG2 4.42Å; F304-V306 HydrophobicContact CE2-CG2 4.48Å; F304-V317 HydrophobicContact CB-CG1 4.32Å; F304-V317 HydrophobicContact CD2-CG1 4.29Å; F304-S318 CarbonylContact C-O 3.55Å; F304-S318 WeakPolarHBondContact CA-O 3.41Å; F304-S318 WeakPolarHBondContact CB-O 3.48Å; F304-V319 HydrophobicContact CB-CB 4.48Å; F304-V319 HydrophobicContact CB-CG2 3.98Å
305I87.4Confident79.7Confident15 Ų1575 Ų758%0.07742%0.42CS..EExtended strand (participates in β ladder)trans-137.5150.1168.268172.8000110.1M286 A291 L295 V317 S318M286-I305 HydrophobicContact CG-CD1 3.87Å; A291-I305 HydrophobicContact CB-CD1 3.43Å; A291-I305 VanDerWaalsContact CB-CD1 3.43Å; A291-I305 HydrophobicContact CB-CG1 4.23Å; L295-I305 HydrophobicContact CD1-CG1 4.32Å; L295-I305 HydrophobicContact CD2-CG2 4.26Å; I305-V317 WeakPolarHBondContact O-CA 3.44Å; I305-S318 PolarHBondContact N-O 3.13Å; I305-S318 PolarHBondContact O-N 3.36Å
306V87Confident79.5Confident12 Ų1275 Ų757%0.07342%0.419CS..EExtended strand (participates in β ladder)trans-109.5132.9173.6-172.40000109W281 Y282 S283 F304 T316 V317W281-V306 HydrophobicContact CD2-CG2 4.42Å; W281-V306 HydrophobicContact CE3-CB 3.62Å; W281-V306 HydrophobicContact CE3-CG2 3.35Å; W281-V306 HydrophobicContact CZ3-CB 3.67Å; W281-V306 HydrophobicContact CZ3-CG1 4.14Å; W281-V306 HydrophobicContact CZ3-CG2 3.52Å; W281-V306 PolarHBondContact O-N 3.47Å; Y282-V306 CarbonylContact C-O 3.52Å; Y282-V306 WeakPolarHBondContact CA-O 3.34Å; Y282-V306 HydrophobicContact CD2-CB 4.18Å; Y282-V306 HydrophobicContact CD2-CG1 4.03Å; S283-V306 PolarHBondContact N-O 2.81Å; F304-V306 HydrophobicContact CD2-CG2 4.42Å; F304-V306 HydrophobicContact CE2-CG2 4.48Å; V306-T316 WeakPolarHBondContact CA-O 3.34Å; V306-V317 HydrophobicContact CG2-CG1 4.44Å; V306-V317 HydrophobicContact CG2-CG2 4.04Å
307R87.2Confident79.6Confident12 Ų1270.1 Ų70.15%0.04540%0.4CS..EExtended strand (participates in β ladder)trans-140.2163.3-177.358.7179.7179.277.11111.2S283 M286 S309 Y315 T316 S318 H333S283-R307 WeakPolarHBondContact O-CA 3.41Å; S283-R307 WeakPolarHBondContact O-CB 3.37Å; M286-R307 HydrophobicContact CB-CB 4.03Å; M286-R307 WeakPolarHBondContact O-CD 3.46Å; R307-S309 PolarHBondContact O-N 3.01Å; R307-Y315 CarbonylContact O-C 3.56Å; R307-Y315 WeakPolarHBondContact O-CA 3.42Å; R307-T316 PolarHBondContact N-O 3.27Å; R307-T316 PolarHBondContact O-N 3.25Å; R307-S318 PolarHBondContact NE-OG 3.3Å; R307-H333 PolarHBondContact NH2-ND1 3.31Å
308D82.8Confident79.7Confident57 Ų5762.8 Ų62.831%0.30537%0.366SS..EExtended strand (participates in β ladder)trans-62.2136.6172.1-72.8-5.3000110.4Y282 K284Y282-D308 PolarHBondContact OH-OD1 3.42Å; K284-D308 WeakPolarHBondContact CG-OD2 3.32Å; K284-D308 WeakPolarHBondContact O-CB 3.39Å
309S78.1Confident79.8Confident19 Ų1959.3 Ų59.313%0.13335%0.352CS..  trans-74.6152.9173.6-161.50000109.7R307 K311 K314 T316R307-S309 PolarHBondContact O-N 3.01Å; S309-K311 PolarHBondContact O-N 3.31Å; S309-K314 WeakPolarHBondContact CB-O 3.31Å; S309-K314 PolarHBondContact N-O 3.22Å; S309-T316 WeakPolarHBondContact CA-OG1 3.49Å; S309-T316 WeakPolarHBondContact CB-OG1 3.46Å; S309-T316 PolarHBondContact OG-OG1 2.74Å
310S70.5Confident80.1Confident124 Ų12458.3 Ų58.387%0.86734%0.34SS*.SBendtrans-61.9-12.5170.3-23.90000112.6
311K63.8Low80Confident141 Ų14153.4 Ų53.461%0.61332%0.324SS*.SBendtrans-97.4126.2173.7-63.2-179.3-179.6179.60108.9S309 G313 K314S309-K311 PolarHBondContact O-N 3.31Å; K311-G313 PolarHBondContact O-N 2.79Å; K311-K314 HydrophobicContact CB-CD 4.49Å; K311-K314 PolarHBondContact O-N 3.09Å
312A62.8Low79.8Confident107 Ų10751 Ų5188%0.88431%0.312SS*.THydrogen-bonded Turntrans-53.8133.6-179.600000112.2
313G66.4Low79.1Confident78 Ų7851.6 Ų51.680%0.80431%0.309SS*.THydrogen-bonded Turntrans74.518.317700000115.7K311K311-G313 PolarHBondContact O-N 2.79Å
314K76.3Confident77.6Confident81 Ų8158.5 Ų58.535%0.35235%0.348SS..  trans-126.8155.1174.7-63.8-166.5176.8-159.90111.3S309 K311 V335S309-K314 WeakPolarHBondContact CB-O 3.31Å; S309-K314 PolarHBondContact N-O 3.22Å; K311-K314 HydrophobicContact CB-CD 4.49Å; K311-K314 PolarHBondContact O-N 3.09Å; K314-V335 HydrophobicContact CB-CG1 4.43Å; K314-V335 HydrophobicContact CD-CG1 4.06Å
315Y82.9Confident75.9Confident75 Ų7556.9 Ų56.929%0.29436%0.36SS..EExtended strand (participates in β ladder)trans-108.7164.6173.6-52.6-75.1000111.3Y282 R307 V336Y282-Y315 AromaticContact CE2-CD1 3.82Å; Y282-Y315 HydrophobicContact CE2-CD1 3.82Å; Y282-Y315 AromaticContact CE2-CE1 3.86Å; Y282-Y315 HydrophobicContact CE2-CE1 3.86Å; R307-Y315 CarbonylContact O-C 3.56Å; R307-Y315 WeakPolarHBondContact O-CA 3.42Å; Y315-V336 PolarHBondContact O-N 3.01Å
316T83.3Confident74.5Confident5 Ų559.5 Ų59.53%0.03137%0.374CS..EExtended strand (participates in β ladder)trans-133.9129.2173.8-50.50000109.6V306 R307 S309 H333 Y334V306-T316 WeakPolarHBondContact CA-O 3.34Å; R307-T316 PolarHBondContact N-O 3.27Å; R307-T316 PolarHBondContact O-N 3.25Å; S309-T316 WeakPolarHBondContact CA-OG1 3.49Å; S309-T316 WeakPolarHBondContact CB-OG1 3.46Å; S309-T316 PolarHBondContact OG-OG1 2.74Å; T316-H333 HydrophobicContact CG2-CB 4.11Å; T316-Y334 CarbonylContact C-O 3.54Å; T316-Y334 WeakPolarHBondContact CA-O 3.39Å; T316-Y334 WeakPolarHBondContact CG2-O 3.35Å
317V86.6Confident73.3Confident18 Ų1864.5 Ų64.511%0.10941%0.407CS..EExtended strand (participates in β ladder)trans-94.5120.9170-170.80000108.6F304 I305 V306 V319 H333 Y334 V336 L346F304-V317 HydrophobicContact CB-CG1 4.32Å; F304-V317 HydrophobicContact CD2-CG1 4.29Å; I305-V317 WeakPolarHBondContact O-CA 3.44Å; V306-V317 HydrophobicContact CG2-CG1 4.44Å; V306-V317 HydrophobicContact CG2-CG2 4.04Å; V317-V319 HydrophobicContact CG1-CG2 3.8Å; V317-H333 CarbonylContact O-C 3.6Å; V317-H333 WeakPolarHBondContact O-CA 2.99Å; V317-Y334 PolarHBondContact N-O 3.49Å; V317-Y334 PolarHBondContact O-N 3.08Å; V317-V336 HydrophobicContact CG2-CG2 3.63Å; V317-L346 HydrophobicContact CB-CD2 4.07Å; V317-L346 HydrophobicContact CG2-CD2 3.51Å
318S86.2Confident72.3Confident0 Ų071.9 Ų71.90%044%0.442CS..EExtended strand (participates in β ladder)trans-102.5123.6173.5-64.40000108.2L295 F304 I305 R307 R332 H333L295-S318 WeakPolarHBondContact CD1-O 3.46Å; F304-S318 CarbonylContact C-O 3.55Å; F304-S318 WeakPolarHBondContact CA-O 3.41Å; F304-S318 WeakPolarHBondContact CB-O 3.48Å; I305-S318 PolarHBondContact N-O 3.13Å; I305-S318 PolarHBondContact O-N 3.36Å; R307-S318 PolarHBondContact NE-OG 3.3Å; S318-R332 CarbonylContact C-O 3.59Å; S318-R332 WeakPolarHBondContact CA-O 3.42Å; S318-H333 PolarHBondContact OG-CE1 3.38Å; S318-H333 VanDerWaalsContact OG-CE1 3.22Å; S318-H333 PolarHBondContact OG-ND1 2.94Å
319V86.7Confident71.8Confident38 Ų3869.5 Ų69.523%0.2343%0.431CS..EExtended strand (participates in β ladder)trans-124.6132.8-175.3-172.80000110G303 F304 V317 I331 R332 Y334G303-V319 CarbonylContact O-C 3.46Å; G303-V319 WeakPolarHBondContact O-CA 3.4Å; F304-V319 HydrophobicContact CB-CB 4.48Å; F304-V319 HydrophobicContact CB-CG2 3.98Å; V317-V319 HydrophobicContact CG1-CG2 3.8Å; V319-I331 CarbonylContact O-C 3.55Å; V319-I331 VanDerWaalsContact O-CA 3.31Å; V319-I331 WeakPolarHBondContact O-CA 3.39Å; V319-R332 PolarHBondContact N-O 3.32Å; V319-R332 PolarHBondContact O-N 3.25Å; V319-Y334 HydrophobicContact CB-CE2 4.39Å; V319-Y334 HydrophobicContact CG2-CD2 4.14Å; V319-Y334 HydrophobicContact CG2-CE2 4.16Å
320F85Confident71.9Confident5 Ų571.6 Ų71.62%0.02244%0.443CS..EExtended strand (participates in β ladder)trans-84.8122172-173.1-96.3000110.6L295 K296 K300 G302 G303 K322 I331L295-F320 HydrophobicContact CB-CB 4.27Å; K296-F320 HydrophobicContact CG-CE2 4.17Å; K300-F320 WeakPolarHBondContact O-CD1 3.31Å; G302-F320 PolarHBondContact N-O 3.13Å; G303-F320 PolarHBondContact O-N 3.13Å; F320-K322 HydrophobicContact CE1-CD 4.12Å; F320-K322 HydrophobicContact CE1-CG 3.92Å; F320-K322 HydrophobicContact CZ-CG 4.31Å; F320-I331 HydrophobicContact CD2-CD1 4.28Å; F320-I331 HydrophobicContact CD2-CG1 3.97Å
321A79.1Confident72.4Confident30 Ų3066.5 Ų66.525%0.24841%0.406CS..EExtended strand (participates in β ladder)trans-121.2127178.400000110G329 V330A321-G329 CarbonylContact O-C 3.42Å; A321-G329 WeakPolarHBondContact O-CA 3.39Å; A321-V330 HydrophobicContact CB-CG1 4.29Å; A321-V330 PolarHBondContact N-O 2.86Å; A321-V330 PolarHBondContact O-N 3.2Å
322K74.9Confident73.1Confident94 Ų9463.6 Ų63.641%0.40939%0.391SS..EExtended strand (participates in β ladder)trans-97.2136.8167.2-102.3171.4176.3164.70108.4G299 E301 F320G299-K322 PolarHBondContact O-NZ 3.12Å; E301-K322 HydrophobicContact CG-CB 4.41Å; F320-K322 HydrophobicContact CE1-CD 4.12Å; F320-K322 HydrophobicContact CE1-CG 3.92Å; F320-K322 HydrophobicContact CZ-CG 4.31Å
323S61.1Low73.9Confident55 Ų5560.6 Ų60.639%0.38536%0.358SS..EExtended strand (participates in β ladder)trans-112.9148.1170.3-169.10000108.6G325 D326S323-G325 PolarHBondContact O-N 2.86Å; S323-D326 PolarHBondContact O-N 2.85Å
324T53Low74.4Confident161 Ų16159.9 Ų59.999%0.98833%0.332SS*.THydrogen-bonded Turntrans-56.9-15.9178.443.90000113.8
325G53.1Low74.4Confident67 Ų6758 Ų5869%0.69133%0.327SS*.THydrogen-bonded Turntrans-106.7-0.6175.200000116.5S323S323-G325 PolarHBondContact O-N 2.86Å
326D58Low74Confident71 Ų7155.4 Ų55.438%0.3832%0.319SS..EExtended strand (participates in β ladder)trans-136.692.1-178.9-170.7-2.7000111.2S323 Q328 G329S323-D326 PolarHBondContact O-N 2.85Å; D326-Q328 PolarHBondContact O-N 2.94Å; D326-Q328 PolarHBondContact OD1-N 3.45Å; D326-G329 PolarHBondContact O-N 3.17Å
327P60.9Low73.3Confident116 Ų11656.3 Ų56.375%0.75333%0.325SS*.EExtended strand (participates in β ladder)trans-68.2-15.2-174.724.7-31.3000114G329P327-G329 VanDerWaalsContact C-N 3.34Å
328Q66Low72Confident168 Ų16859.2 Ų59.279%0.78535%0.346SS*.EExtended strand (participates in β ladder)trans-76.6-20.5176.9-90.7178.3-0.700113.3D326D326-Q328 PolarHBondContact O-N 2.94Å; D326-Q328 PolarHBondContact OD1-N 3.45Å
329G72.1Confident70.5Confident7 Ų761 Ų617%0.07236%0.357CS..EExtended strand (participates in β ladder)trans68.9145-177.500000113.2A321 D326 P327A321-G329 CarbonylContact O-C 3.42Å; A321-G329 WeakPolarHBondContact O-CA 3.39Å; D326-G329 PolarHBondContact O-N 3.17Å; P327-G329 VanDerWaalsContact C-N 3.34Å
330V81.6Confident68.9Low63 Ų6365.8 Ų65.838%0.38239%0.389SS..EExtended strand (participates in β ladder)trans-117.1139-177.7680000110.3A321 R332A321-V330 HydrophobicContact CB-CG1 4.29Å; A321-V330 PolarHBondContact N-O 2.86Å; A321-V330 PolarHBondContact O-N 3.2Å; V330-R332 HydrophobicContact CG1-CG 4.42Å
331I81.3Confident67.5Low17 Ų1772.6 Ų72.69%0.08742%0.421CS..EExtended strand (participates in β ladder)trans-92.1126.1168.9-67.1119000109.6E292 L295 K296 V319 F320E292-I331 HydrophobicContact CB-CD1 3.86Å; E292-I331 HydrophobicContact CG-CB 4.13Å; E292-I331 HydrophobicContact CG-CD1 4.07Å; E292-I331 HydrophobicContact CG-CG2 4.07Å; E292-I331 WeakPolarHBondContact O-CD1 3.41Å; L295-I331 HydrophobicContact CB-CD1 4.25Å; L295-I331 HydrophobicContact CB-CG1 3.98Å; L295-I331 HydrophobicContact CD1-CG1 4.24Å; L295-I331 HydrophobicContact CD1-CG2 4.08Å; K296-I331 HydrophobicContact CD-CD1 3.92Å; K296-I331 HydrophobicContact CG-CD1 3.59Å; V319-I331 CarbonylContact O-C 3.55Å; V319-I331 VanDerWaalsContact O-CA 3.31Å; V319-I331 WeakPolarHBondContact O-CA 3.39Å; F320-I331 HydrophobicContact CD2-CD1 4.28Å; F320-I331 HydrophobicContact CD2-CG1 3.97Å
332R78.6Confident66.5Low79 Ų7975.8 Ų75.830%0.29844%0.442SS..EExtended strand (participates in β ladder)trans-103.3140.2173.3-62.2-174.1179.5-102.52.5109.3S318 V319 V330 Y334 L417 G418S318-R332 CarbonylContact C-O 3.59Å; S318-R332 WeakPolarHBondContact CA-O 3.42Å; V319-R332 PolarHBondContact N-O 3.32Å; V319-R332 PolarHBondContact O-N 3.25Å; V330-R332 HydrophobicContact CG1-CG 4.42Å; R332-Y334 HydrophobicContact CB-CD2 4.41Å; R332-Y334 HydrophobicContact CB-CE2 3.51Å; R332-Y334 WeakPolarHBondContact CD-OH 3.12Å; R332-L417 PolarHBondContact NH2-O 3.26Å; R332-G418 VanDerWaalsContact CZ-O 3.31Å; R332-G418 PolarHBondContact NH1-O 3.2Å; R332-G418 PolarHBondContact NH2-O 3.32Å
333H79.1Confident65.7Low45 Ų4575.7 Ų75.721%0.20844%0.442CS..EExtended strand (participates in β ladder)trans-117.3122-179.3-61.1-95.3000109.3E292 R307 T316 V317 S318E292-H333 WeakPolarHBondContact CG-NE2 3.36Å; E292-H333 IonicContact OE1-CD2 2.86Å; E292-H333 IonicContact OE1-CE1 3.29Å; E292-H333 IonicContact OE1-NE2 2.69Å; E292-H333 PolarHBondContact OE1-NE2 2.89Å; R307-H333 PolarHBondContact NH2-ND1 3.31Å; T316-H333 HydrophobicContact CG2-CB 4.11Å; V317-H333 CarbonylContact O-C 3.6Å; V317-H333 WeakPolarHBondContact O-CA 2.99Å; S318-H333 PolarHBondContact OG-CE1 3.38Å; S318-H333 VanDerWaalsContact OG-CE1 3.22Å; S318-H333 PolarHBondContact OG-ND1 2.94Å
334Y75.9Confident65.8Low63 Ų6380 Ų8025%0.24745%0.451CS..EExtended strand (participates in β ladder)trans-117124-178.5-58-85.7000109.2T316 V317 V319 R332 A348T316-Y334 CarbonylContact C-O 3.54Å; T316-Y334 WeakPolarHBondContact CA-O 3.39Å; T316-Y334 WeakPolarHBondContact CG2-O 3.35Å; V317-Y334 PolarHBondContact N-O 3.49Å; V317-Y334 PolarHBondContact O-N 3.08Å; V319-Y334 HydrophobicContact CB-CE2 4.39Å; V319-Y334 HydrophobicContact CG2-CD2 4.14Å; V319-Y334 HydrophobicContact CG2-CE2 4.16Å; R332-Y334 HydrophobicContact CB-CD2 4.41Å; R332-Y334 HydrophobicContact CB-CE2 3.51Å; R332-Y334 WeakPolarHBondContact CD-OH 3.12Å; Y334-A348 HydrophobicContact CD1-CB 4.36Å; Y334-A348 HydrophobicContact CE1-CB 4.21Å
335V76.9Confident66.1Low42 Ų4272.9 Ų72.926%0.25541%0.406SS..EExtended strand (participates in β ladder)trans-78.6132.1177.8179.40000108.7K314 A347K314-V335 HydrophobicContact CB-CG1 4.43Å; K314-V335 HydrophobicContact CD-CG1 4.06Å; V335-A347 HydrophobicContact CB-CB 4.23Å; V335-A347 WeakPolarHBondContact O-CB 3.15Å; V335-A347 PolarHBondContact O-N 3.37Å
336V74.9Confident66Low20 Ų2073 Ų7312%0.12139%0.391CS..EExtended strand (participates in β ladder)trans-81.9119.4171.4-1740000108.2Y315 V317 Y344 Y345 L346Y315-V336 PolarHBondContact O-N 3.01Å; V317-V336 HydrophobicContact CG2-CG2 3.63Å; V336-Y344 HydrophobicContact CG1-CD1 3.91Å; V336-Y344 HydrophobicContact CG1-CG 4.5Å; V336-Y345 WeakPolarHBondContact CA-O 3.37Å; V336-L346 HydrophobicContact CG2-CD2 4.08Å
337C68.8Low65.5Low24 Ų2470.3 Ų70.316%0.16238%0.379CS..EExtended strand (participates in β ladder)trans-107.8136.1173.9-71.10000109.4Y344 Y345 L352C337-Y344 CarbonylContact O-C 3.58Å; C337-Y344 WeakPolarHBondContact O-CA 3.39Å; C337-Y345 PolarHBondContact N-O 3.32Å; C337-Y345 PolarHBondContact O-N 3.17Å; C337-L352 HydrophobicContact CB-CD2 4.04Å
338S58.7Low65.2Low79 Ų7967.1 Ų67.155%0.55236%0.362SS*.EExtended strand (participates in β ladder)trans-102.4142170.351.60000110.8Q343S338-Q343 CarbonylContact C-O 3.54Å; S338-Q343 VanDerWaalsContact CA-O 3.29Å; S338-Q343 WeakPolarHBondContact CA-O 3.4Å
339T55.7Low65Low36 Ų3666.5 Ų66.522%0.22135%0.352CS..  trans-86.8162.6170.264.50000110.8Q341 S342 Q343 Y345T339-Q341 PolarHBondContact O-N 3.24Å; T339-Q341 PolarHBondContact OG1-N 3.03Å; T339-S342 PolarHBondContact O-N 3.41Å; T339-Q343 PolarHBondContact N-O 3.46Å; T339-Q343 WeakPolarHBondContact OG1-CB 3.36Å; T339-Q343 PolarHBondContact OG1-N 3.49Å; T339-Y345 HydrophobicContact CG2-CD2 3.79Å; T339-Y345 HydrophobicContact CG2-CE2 3.31Å
340P52.8Low64.8Low139 Ų13970.3 Ų70.390%0.90337%0.371SS*.THydrogen-bonded Turntrans-58.8-9.7169.8-23.934.6000114.6
341Q54.2Low64.5Low149 Ų14968.1 Ų68.170%0.69636%0.358SS*.THydrogen-bonded Turntrans-10217.5177.7-63.7143.1-4.100111.7T339 Q343T339-Q341 PolarHBondContact O-N 3.24Å; T339-Q341 PolarHBondContact OG1-N 3.03Å; Q341-Q343 VanDerWaalsContact C-N 3.27Å; Q341-Q343 PolarHBondContact O-N 2.95Å
342S59.9Low64Low97 Ų9768.5 Ų68.568%0.67836%0.36SS*.SBendtrans59.728.8179.6-54.80000115.2T339T339-S342 PolarHBondContact O-N 3.41Å
343Q56.7Low63.8Low91 Ų9167.3 Ų67.343%0.42536%0.362SS..  trans-97.1139.4171.9-65.6-178.7-20.300110.9S338 T339 Q341 Y345S338-Q343 CarbonylContact C-O 3.54Å; S338-Q343 VanDerWaalsContact CA-O 3.29Å; S338-Q343 WeakPolarHBondContact CA-O 3.4Å; T339-Q343 PolarHBondContact N-O 3.46Å; T339-Q343 WeakPolarHBondContact OG1-CB 3.36Å; T339-Q343 PolarHBondContact OG1-N 3.49Å; Q341-Q343 VanDerWaalsContact C-N 3.27Å; Q341-Q343 PolarHBondContact O-N 2.95Å; Q343-Y345 HydrophobicContact CB-CD2 4.43Å; Q343-Y345 HydrophobicContact CB-CE2 3.65Å; Q343-Y345 PolarHBondContact OE1-OH 2.9Å
344Y63.7Low63.4Low147 Ų14766.4 Ų66.458%0.57636%0.358SS*.EExtended strand (participates in β ladder)trans-101.7141-179.9-59.5-82.9000112V336 C337V336-Y344 HydrophobicContact CG1-CD1 3.91Å; V336-Y344 HydrophobicContact CG1-CG 4.5Å; C337-Y344 CarbonylContact O-C 3.58Å; C337-Y344 WeakPolarHBondContact O-CA 3.39Å
345Y59.1Low63.1Low10 Ų1069.8 Ų69.84%0.03938%0.381CS..EExtended strand (participates in β ladder)trans-137142.5-178-66.6-103.5000110.7V336 C337 T339 Q343 L352 V353 N354 K360V336-Y345 WeakPolarHBondContact CA-O 3.37Å; C337-Y345 PolarHBondContact N-O 3.32Å; C337-Y345 PolarHBondContact O-N 3.17Å; T339-Y345 HydrophobicContact CG2-CD2 3.79Å; T339-Y345 HydrophobicContact CG2-CE2 3.31Å; Q343-Y345 HydrophobicContact CB-CD2 4.43Å; Q343-Y345 HydrophobicContact CB-CE2 3.65Å; Q343-Y345 PolarHBondContact OE1-OH 2.9Å; Y345-L352 HydrophobicContact CD1-CB 3.92Å; Y345-L352 HydrophobicContact CG-CB 4.23Å; Y345-L352 HydrophobicContact CG-CD1 4.45Å; Y345-V353 WeakPolarHBondContact CA-O 3.23Å; Y345-N354 HydrophobicContact CD1-CB 3.75Å; Y345-N354 HydrophobicContact CE1-CB 3.54Å; Y345-K360 HydrophobicContact CE1-CD 3.99Å; Y345-K360 PolarHBondContact OH-NZ 3.29Å; Y345-K360 VanDerWaalsContact OH-NZ 3.09Å
346L52.2Low62.6Low70 Ų7074.6 Ų74.637%0.36640%0.401SS..EExtended strand (participates in β ladder)trans-90.8125.4172.2-69.1176.3000111.1V317 V336 L352 V353V317-L346 HydrophobicContact CB-CD2 4.07Å; V317-L346 HydrophobicContact CG2-CD2 3.51Å; V336-L346 HydrophobicContact CG2-CD2 4.08Å; L346-L352 CarbonylContact O-C 3.45Å; L346-L352 VanDerWaalsContact O-CA 3.28Å; L346-L352 WeakPolarHBondContact O-CA 3.49Å; L346-V353 PolarHBondContact N-O 3.04Å; L346-V353 PolarHBondContact O-N 2.83Å
347A47.1Very low62.3Low15 Ų1576.1 Ų76.112%0.12442%0.42CS..EExtended strand (participates in β ladder)trans-91.1118.3179.500000112.9V335 C351 L352V335-A347 HydrophobicContact CB-CB 4.23Å; V335-A347 WeakPolarHBondContact O-CB 3.15Å; V335-A347 PolarHBondContact O-N 3.37Å; A347-C351 CarbonylContact C-O 3.53Å; A347-C351 WeakPolarHBondContact CA-O 3.45Å; A347-L352 HydrophobicContact CB-CD2 3.6Å
348A54.4Low62.5Low48 Ų4878.3 Ų78.340%0.39743%0.432SS..EExtended strand (participates in β ladder)trans-103.6107.1162.100000108.9Y334 N350 C351Y334-A348 HydrophobicContact CD1-CB 4.36Å; Y334-A348 HydrophobicContact CE1-CB 4.21Å; A348-N350 VanDerWaalsContact C-N 3.29Å; A348-N350 PolarHBondContact O-N 3.12Å; A348-C351 PolarHBondContact N-O 3.31Å; A348-C351 PolarHBondContact O-N 3.33Å
349R61.4Low63.2Low156 Ų15679 Ų7959%0.58943%0.433SS*.THydrogen-bonded Turntrans43.3-73.6-175-92.9-177.6160.7-136.30.2116W387R349-W387 VanDerWaalsContact NH1-CE3 3.3Å
350N68.8Low64.1Low87 Ų8781.9 Ų81.947%0.46544%0.443SS..THydrogen-bonded Turntrans-135.221.1177.6-62.8-31.7000113.3A348 S362A348-N350 VanDerWaalsContact C-N 3.29Å; A348-N350 PolarHBondContact O-N 3.12Å; N350-S362 VanDerWaalsContact C-OG 3.3Å; N350-S362 PolarHBondContact O-N 3.26Å; N350-S362 VanDerWaalsContact O-O 3.09Å; N350-S362 PolarHBondContact O-OG 2.99Å
351C74.2Confident65Low16 Ų1679.3 Ų79.311%0.10842%0.424CS..EExtended strand (participates in β ladder)trans-129.5142.7174.1-71.80000109.7A347 A348 V359 K360A347-C351 CarbonylContact C-O 3.53Å; A347-C351 WeakPolarHBondContact CA-O 3.45Å; A348-C351 PolarHBondContact N-O 3.31Å; A348-C351 PolarHBondContact O-N 3.33Å; C351-V359 HydrophobicContact CB-CG1 4.03Å; C351-K360 CarbonylContact C-O 3.52Å; C351-K360 WeakPolarHBondContact CA-O 3.13Å
352L71.6Confident65.5Low26 Ų2672.8 Ų72.814%0.13640%0.395CS..EExtended strand (participates in β ladder)trans-113.2138.4179.4-73173.6000109.4C337 Y345 L346 A347 V359 K360 S362C337-L352 HydrophobicContact CB-CD2 4.04Å; Y345-L352 HydrophobicContact CD1-CB 3.92Å; Y345-L352 HydrophobicContact CG-CB 4.23Å; Y345-L352 HydrophobicContact CG-CD1 4.45Å; L346-L352 CarbonylContact O-C 3.45Å; L346-L352 VanDerWaalsContact O-CA 3.28Å; L346-L352 WeakPolarHBondContact O-CA 3.49Å; A347-L352 HydrophobicContact CB-CD2 3.6Å; L352-V359 CarbonylContact O-C 3.39Å; L352-V359 VanDerWaalsContact O-CA 3.32Å; L352-V359 WeakPolarHBondContact O-CA 3.43Å; L352-K360 PolarHBondContact N-O 2.88Å; L352-K360 PolarHBondContact O-N 3.4Å; L352-S362 VanDerWaalsContact CD1-CB 3.48Å
353V73.3Confident65.4Low54 Ų5473.6 Ų73.633%0.32739%0.392SS..EExtended strand (participates in β ladder)trans-117.8131.7172.8-167.10000108.7Y345 L346 V358 V359Y345-V353 WeakPolarHBondContact CA-O 3.23Å; L346-V353 PolarHBondContact N-O 3.04Å; L346-V353 PolarHBondContact O-N 2.83Å; V353-V358 WeakPolarHBondContact CA-O 3.36Å; V353-V359 HydrophobicContact CG2-CG2 4.13Å
354N71.1Confident65.5Low26 Ų2675.5 Ų75.514%0.13940%0.399CS..  trans-90.5177.7172.972.1-5.3000112.4Y345 Q356 G357 V358Y345-N354 HydrophobicContact CD1-CB 3.75Å; Y345-N354 HydrophobicContact CE1-CB 3.54Å; N354-Q356 PolarHBondContact O-N 2.83Å; N354-Q356 PolarHBondContact OD1-N 2.98Å; N354-G357 PolarHBondContact O-N 3.14Å; N354-G357 PolarHBondContact OD1-N 3.2Å; N354-V358 PolarHBondContact N-O 2.96Å; N354-V358 VanDerWaalsContact N-O 3.17Å; N354-V358 WeakPolarHBondContact OD1-CA 3.35Å; N354-V358 VanDerWaalsContact OD1-CB 3.25Å; N354-V358 WeakPolarHBondContact OD1-CB 3.37Å; N354-V358 PolarHBondContact OD1-N 3.33Å; N354-V358 PolarHBondContact OD1-O 3.37Å
355D69.3Low64.6Low134 Ų13472.1 Ų72.172%0.71741%0.409SS*.THydrogen-bonded Turntrans-55.7-29.9175.564-38000114.1G357D355-G357 VanDerWaalsContact C-N 3.27Å; D355-G357 PolarHBondContact O-N 3.16Å
356Q66.4Low63.8Low143 Ų14375.9 Ų75.967%0.66843%0.429SS*.THydrogen-bonded Turntrans-85.16.7176.6-54.6-56.2-49.300113.5N354 V358N354-Q356 PolarHBondContact O-N 2.83Å; N354-Q356 PolarHBondContact OD1-N 2.98Å; Q356-V358 HydrophobicContact CB-CG2 4.22Å; Q356-V358 PolarHBondContact O-N 3.14Å
357G69Low63.2Low51 Ų5174.5 Ų74.553%0.52643%0.426SS..  trans73.48.4-177.800000114.8N354 D355 V359N354-G357 PolarHBondContact O-N 3.14Å; N354-G357 PolarHBondContact OD1-N 3.2Å; D355-G357 VanDerWaalsContact C-N 3.27Å; D355-G357 PolarHBondContact O-N 3.16Å; G357-V359 PolarHBondContact O-N 3.2Å
358V72Confident63Low70 Ų7078.9 Ų78.942%0.42444%0.439SS..  trans-75.3120.9178.1-178.80000109.8V353 N354 Q356 K360V353-V358 WeakPolarHBondContact CA-O 3.36Å; N354-V358 PolarHBondContact N-O 2.96Å; N354-V358 VanDerWaalsContact N-O 3.17Å; N354-V358 WeakPolarHBondContact OD1-CA 3.35Å; N354-V358 VanDerWaalsContact OD1-CB 3.25Å; N354-V358 WeakPolarHBondContact OD1-CB 3.37Å; N354-V358 PolarHBondContact OD1-N 3.33Å; N354-V358 PolarHBondContact OD1-O 3.37Å; Q356-V358 HydrophobicContact CB-CG2 4.22Å; Q356-V358 PolarHBondContact O-N 3.14Å; V358-K360 HydrophobicContact CG1-CG 4.37Å
359V75.1Confident62.3Low94 Ų9483.9 Ų83.957%0.5745%0.449SS*.EExtended strand (participates in β ladder)trans-85.9129.7175.2-171.30000110C351 L352 V353 G357C351-V359 HydrophobicContact CB-CG1 4.03Å; L352-V359 CarbonylContact O-C 3.39Å; L352-V359 VanDerWaalsContact O-CA 3.32Å; L352-V359 WeakPolarHBondContact O-CA 3.43Å; V353-V359 HydrophobicContact CG2-CG2 4.13Å; G357-V359 PolarHBondContact O-N 3.2Å
360K73.3Confident61Low97 Ų9778.8 Ų78.842%0.42243%0.434SS..EExtended strand (participates in β ladder)trans-126.6135.5174.1-63.9-174.4-177.8172.20109.8Y345 C351 L352 V358Y345-K360 HydrophobicContact CE1-CD 3.99Å; Y345-K360 PolarHBondContact OH-NZ 3.29Å; Y345-K360 VanDerWaalsContact OH-NZ 3.09Å; C351-K360 CarbonylContact C-O 3.52Å; C351-K360 WeakPolarHBondContact CA-O 3.13Å; L352-K360 PolarHBondContact N-O 2.88Å; L352-K360 PolarHBondContact O-N 3.4Å; V358-K360 HydrophobicContact CG1-CG 4.37Å
361V72.6Confident59.6Low84 Ų8479.1 Ų79.151%0.50944%0.436SS..EExtended strand (participates in β ladder)trans-66.6137.9173.2-176.70000109.4F364V361-F364 HydrophobicContact CB-CE1 3.92Å; V361-F364 HydrophobicContact CB-CZ 3.72Å; V361-F364 HydrophobicContact CG1-CD1 4.22Å; V361-F364 HydrophobicContact CG1-CE1 3.58Å; V361-F364 HydrophobicContact CG1-CZ 3.8Å; V361-F364 WeakPolarHBondContact O-CE2 3.38Å
362S63.9Low57.7Low12 Ų1282.7 Ų82.78%0.08445%0.454CS..  trans-125.7169.9176.270.10000111.3N350 L352 F364N350-S362 VanDerWaalsContact C-OG 3.3Å; N350-S362 PolarHBondContact O-N 3.26Å; N350-S362 VanDerWaalsContact O-O 3.09Å; N350-S362 PolarHBondContact O-OG 2.99Å; L352-S362 VanDerWaalsContact CD1-CB 3.48Å; S362-F364 PolarHBondContact O-N 3.25Å
363D58.8Low56.2Low115 Ų11586.1 Ų86.162%0.61547%0.472SS*.  trans54.947.2176-66.4-25.7000113.9G365D363-G365 PolarHBondContact O-N 2.99Å
364F57.5Low54.6Low130 Ų13088.4 Ų88.457%0.5748%0.479SS*.G310 helixtrans-58.45.6162.7-52.1-82.6000113.4V361 S362 L366 S367V361-F364 HydrophobicContact CB-CE1 3.92Å; V361-F364 HydrophobicContact CB-CZ 3.72Å; V361-F364 HydrophobicContact CG1-CD1 4.22Å; V361-F364 HydrophobicContact CG1-CE1 3.58Å; V361-F364 HydrophobicContact CG1-CZ 3.8Å; V361-F364 WeakPolarHBondContact O-CE2 3.38Å; S362-F364 PolarHBondContact O-N 3.25Å; F364-L366 VanDerWaalsContact C-N 3.29Å; F364-L366 PolarHBondContact O-N 3.37Å; F364-S367 PolarHBondContact O-N 3.4Å; F364-S367 PolarHBondContact O-OG 3.35Å
365G45.9Very low53.5Low77 Ų7788.7 Ų88.779%0.79448%0.479SS*.G310 helixtrans-80.34.6-171.300000115.6D363D363-G365 PolarHBondContact O-N 2.99Å
366L41.1Very low52.1Low89 Ų8986 Ų8647%0.46647%0.467SS..G310 helixtrans-105.8-17.9168-73.4169.4000112.9F364 R368F364-L366 VanDerWaalsContact C-N 3.29Å; F364-L366 PolarHBondContact O-N 3.37Å; L366-R368 PolarHBondContact O-N 3.18Å; L366-R368 VanDerWaalsContact O-N 3.13Å
367S40.3Very low50.8Low41 Ų4181.4 Ų81.429%0.28745%0.451SS..SBendtrans-7991.9168.223.30000108.6F364 Y369F364-S367 PolarHBondContact O-N 3.4Å; F364-S367 PolarHBondContact O-OG 3.35Å; S367-Y369 PolarHBondContact O-N 2.97Å
368R42.9Very low49.2Very low107 Ų10781.9 Ų81.940%0.40445%0.446SS..  trans-58.1129.4161.8-65.9-174.2-149.3146.64.9106.5L366 V370 T376 S377L366-R368 PolarHBondContact O-N 3.18Å; L366-R368 VanDerWaalsContact O-N 3.13Å; R368-V370 HydrophobicContact CB-CG2 3.82Å; R368-V370 PolarHBondContact O-N 3.46Å; R368-T376 PolarHBondContact NE-O 3.03Å; R368-T376 PolarHBondContact NH1-O 2.93Å; R368-T376 VanDerWaalsContact NH1-O 3.11Å; R368-T376 PolarHBondContact NH1-OG1 3.34Å; R368-T376 PolarHBondContact NH2-O 3.46Å; R368-S377 PolarHBondContact NH2-O 3.14Å
369Y39.2Very low47.1Very low153 Ų15386.1 Ų86.160%0.647%0.472SS*.  trans-71.188.2166.7-72.3-101.9000106.9R123 S367R123-Y369 VanDerWaalsContact NH1-CE2 3.32Å; R123-Y369 VanDerWaalsContact NH1-CZ 3.26Å; S367-Y369 PolarHBondContact O-N 2.97Å
370V35.4Very low45.3Very low48 Ų4885.5 Ų85.529%0.29149%0.485SS..  trans-89.9134169.6-175.10000106.4R368 D372 E374 Y375R368-V370 HydrophobicContact CB-CG2 3.82Å; R368-V370 PolarHBondContact O-N 3.46Å; V370-D372 CarbonylContact C-O 3.55Å; V370-D372 HydrophobicContact CG1-CB 4.23Å; V370-D372 WeakPolarHBondContact CG1-O 3.44Å; V370-D372 PolarHBondContact O-N 2.83Å; V370-E374 WeakPolarHBondContact CG1-O 3.43Å; V370-Y375 VanDerWaalsContact CG2-CB 3.44Å
371L38Very low43.6Very low94 Ų9483.6 Ų83.649%0.49248%0.483SS..SBendtrans-71.8-10.8-180-76.4163.5000112.5I9I9-L371 HydrophobicContact CG1-CD1 4.34Å
372D35.6Very low42.6Very low92 Ų9289.7 Ų89.749%0.49250%0.503SS..SBendtrans-102.6148.4165.1-83.5-38.7000109.6V370 E374V370-D372 CarbonylContact C-O 3.55Å; V370-D372 HydrophobicContact CG1-CB 4.23Å; V370-D372 WeakPolarHBondContact CG1-O 3.44Å; V370-D372 PolarHBondContact O-N 2.83Å; D372-E374 PolarHBondContact O-N 3.15Å
373D40.1Very low42.7Very low98 Ų9892.2 Ų92.252%0.52451%0.513SS..SBendtrans-60.220172.2-90.7-45.9000113.7F398 S399 S400D373-F398 CarbonylContact C-O 3.43Å; D373-F398 CarbonylContact O-C 3.59Å; D373-S399 WeakPolarHBondContact O-CA 2.89Å; D373-S399 WeakPolarHBondContact O-CB 3.12Å; D373-S400 PolarHBondContact OD1-OG 3.32Å
374E38.1Very low43.5Very low101 Ų10189.3 Ų89.347%0.47250%0.5SS..  trans-133.9106.2-179.6-59.5-163176.200110.9V370 D372 K397 F398V370-E374 WeakPolarHBondContact CG1-O 3.43Å; D372-E374 PolarHBondContact O-N 3.15Å; E374-K397 HydrophobicContact CG-CD 4.33Å; E374-K397 HydrophobicContact CG-CG 3.89Å; E374-K397 WeakPolarHBondContact OE1-CD 3.35Å; E374-K397 WeakPolarHBondContact OE1-CE 3.49Å; E374-K397 IonicContact OE1-NZ 2.7Å; E374-K397 PolarHBondContact OE1-NZ 2.83Å; E374-F398 CarbonylContact C-O 3.53Å; E374-F398 WeakPolarHBondContact CA-O 3.4Å; E374-F398 PolarHBondContact N-O 3.32Å
375Y48.2Very low44.6Very low33 Ų3384 Ų8413%0.12948%0.478CS..BIsolated β-bridgetrans-109.5157.9169.367.9-92.8000112.1V370 F398 D403V370-Y375 VanDerWaalsContact CG2-CB 3.44Å; Y375-F398 HydrophobicContact CD1-CB 3.4Å; Y375-F398 VanDerWaalsContact CD1-CB 3.4Å; Y375-F398 HydrophobicContact CD1-CG 4.45Å; Y375-F398 WeakPolarHBondContact CD1-O 3.43Å; Y375-F398 HydrophobicContact CD2-CB 3.6Å; Y375-F398 HydrophobicContact CD2-CD1 4.13Å; Y375-F398 HydrophobicContact CD2-CD2 4.29Å; Y375-F398 AromaticContact CD2-CG 3.8Å; Y375-F398 HydrophobicContact CD2-CG 3.8Å; Y375-F398 HydrophobicContact CE1-CB 3.3Å; Y375-F398 HydrophobicContact CE1-CD1 4.36Å; Y375-F398 HydrophobicContact CE1-CG 4.22Å; Y375-F398 HydrophobicContact CE2-CB 3.48Å; Y375-F398 VanDerWaalsContact CE2-CB 3.48Å; Y375-F398 AromaticContact CE2-CD1 3.38Å; Y375-F398 HydrophobicContact CE2-CD1 3.38Å; Y375-F398 HydrophobicContact CE2-CD2 4.33Å; Y375-F398 HydrophobicContact CE2-CE1 4.05Å; Y375-F398 AromaticContact CE2-CG 3.51Å; Y375-F398 HydrophobicContact CE2-CG 3.51Å; Y375-F398 HydrophobicContact CG-CB 3.55Å; Y375-F398 HydrophobicContact CG-CG 4.25Å; Y375-F398 AromaticContact CZ-CD1 3.51Å; Y375-F398 AromaticContact CZ-CG 3.74Å; Y375-F398 PolarHBondContact N-O 3.49Å; Y375-F398 WeakPolarHBondContact O-CB 3.48Å; Y375-F398 WeakPolarHBondContact O-CD2 3.36Å; Y375-F398 WeakPolarHBondContact OH-CD1 3.39Å; Y375-D403 PolarHBondContact OH-OD1 2.95Å
376T40.6Very low46.6Very low77 Ų7782.5 Ų82.547%0.47245%0.449SS..  trans-111.3153.1173.839.60000110.4R368R368-T376 PolarHBondContact NE-O 3.03Å; R368-T376 PolarHBondContact NH1-O 2.93Å; R368-T376 VanDerWaalsContact NH1-O 3.11Å; R368-T376 PolarHBondContact NH1-OG1 3.34Å; R368-T376 PolarHBondContact NH2-O 3.46Å
377S38.9Very low49Very low47 Ų4779.7 Ų79.733%0.32943%0.432SS..PPolyproline II helixtrans-75.3153.4178.8-178.10000112.6R368R368-S377 PolarHBondContact NH2-O 3.14Å
378S35.5Very low51.2Low60 Ų6078 Ų7842%0.4242%0.42SS..PPolyproline II helixtrans-76.2131.2170.446.80000111.4G380S378-G380 PolarHBondContact O-N 2.67Å
379V28.9Very low53.5Low159 Ų15973.1 Ų73.196%0.96440%0.402SS*.THydrogen-bonded Turntrans-57.2119.6176.1-177.60000110.3
380G35.5Very low55.9Low82 Ų8266.5 Ų66.585%0.84538%0.378SS*.THydrogen-bonded Turntrans122.7-7.8166.600000118.1S378S378-G380 PolarHBondContact O-N 2.67Å
381S38.1Very low58.2Low56 Ų5665.2 Ų65.239%0.39237%0.369SS..SBendtrans-94.4142.3173.752.70000112.1F383S381-F383 PolarHBondContact O-N 3.36Å
382K52.9Low60.4Low212 Ų21260.8 Ų60.892%0.92235%0.346SS*.  trans-55106.3173-68.9-177.8179.4-178.40109.5
383F65.5Low62.6Low66 Ų6658.3 Ų58.329%0.28933%0.332SS..  trans-65.2131-174.5176.1-93.4000111.3S381 V385 V392 L393 F398S381-F383 PolarHBondContact O-N 3.36Å; F383-V385 VanDerWaalsContact C-N 3.28Å; F383-V385 HydrophobicContact CD1-CB 4.39Å; F383-V385 HydrophobicContact CD1-CG2 3.5Å; F383-V385 VanDerWaalsContact CD1-CG2 3.5Å; F383-V385 HydrophobicContact CE1-CB 4.48Å; F383-V385 HydrophobicContact CE1-CG2 3.87Å; F383-V385 PolarHBondContact O-N 3.35Å; F383-V392 HydrophobicContact CE2-CG1 4.11Å; F383-V392 HydrophobicContact CZ-CG1 3.83Å; F383-L393 HydrophobicContact CE1-CD2 3.65Å; F383-L393 HydrophobicContact CZ-CD2 4.1Å; F383-F398 AromaticContact CE2-CZ 3.89Å; F383-F398 HydrophobicContact CE2-CZ 3.89Å
384P76.2Confident64.3Low53 Ų5358.4 Ų58.434%0.34433%0.331SS..  trans-83.862.4-170.235.4-37.6000112.7R386 W387 S388P384-R386 VanDerWaalsContact C-N 3.28Å; P384-R386 PolarHBondContact O-N 3.21Å; P384-W387 HydrophobicContact CB-CE3 4.3Å; P384-W387 PolarHBondContact O-N 2.85Å; P384-S388 PolarHBondContact O-N 2.95Å; P384-S388 PolarHBondContact O-OG 2.92Å
385V80.5Confident66Low19 Ų1961.9 Ų61.912%0.11534%0.341CS..G310 helixtrans-43.1-48-173.7178.20000114.2F383 W387 S388 L393 N427 A431F383-V385 VanDerWaalsContact C-N 3.28Å; F383-V385 HydrophobicContact CD1-CB 4.39Å; F383-V385 HydrophobicContact CD1-CG2 3.5Å; F383-V385 VanDerWaalsContact CD1-CG2 3.5Å; F383-V385 HydrophobicContact CE1-CB 4.48Å; F383-V385 HydrophobicContact CE1-CG2 3.87Å; F383-V385 PolarHBondContact O-N 3.35Å; V385-W387 PolarHBondContact O-N 3.13Å; V385-W387 VanDerWaalsContact O-N 3.16Å; V385-S388 PolarHBondContact O-N 2.66Å; V385-S388 VanDerWaalsContact O-N 3.08Å; V385-L393 HydrophobicContact CB-CD2 4.46Å; V385-L393 HydrophobicContact CG1-CD2 3.9Å; V385-N427 HydrophobicContact CB-CB 4.06Å; V385-N427 HydrophobicContact CG1-CB 4.15Å; V385-N427 VanDerWaalsContact CG1-O 3.29Å; V385-N427 WeakPolarHBondContact CG1-O 3.4Å; V385-N427 HydrophobicContact CG2-CB 3.95Å; V385-A431 HydrophobicContact CG1-CB 4.08Å
386R87.3Confident67Low45 Ų4563.1 Ų63.117%0.1735%0.354CS..G310 helixtrans-70.4-10-174-62.3172.3165.7124.95.8115P384 P421 Y422 F425 N427 T430P384-R386 VanDerWaalsContact C-N 3.28Å; P384-R386 PolarHBondContact O-N 3.21Å; R386-P421 HydrophobicContact CB-CB 4.32Å; R386-P421 WeakPolarHBondContact CD-O 3.35Å; R386-P421 PolarHBondContact NE-O 2.82Å; R386-Y422 HydrophobicContact CB-CD2 4.21Å; R386-Y422 HydrophobicContact CG-CD2 4.44Å; R386-F425 PolarHBondContact NH2-O 3.49Å; R386-N427 PolarHBondContact NH1-OD1 2.86Å; R386-T430 HydrophobicContact CG-CG2 4.1Å
387W90.4Very high68.5Low30 Ų3063.7 Ų63.711%0.11435%0.35CS..G310 helixtrans-108.3-2.7175.6-69.5-100000112.1R349 P384 V385 A406 V409 E413 M420 P421R349-W387 VanDerWaalsContact NH1-CE3 3.3Å; P384-W387 HydrophobicContact CB-CE3 4.3Å; P384-W387 PolarHBondContact O-N 2.85Å; V385-W387 PolarHBondContact O-N 3.13Å; V385-W387 VanDerWaalsContact O-N 3.16Å; W387-A406 HydrophobicContact CB-CB 4.47Å; W387-V409 VanDerWaalsContact CD1-CG1 3.46Å; W387-V409 HydrophobicContact CD2-CG1 4.41Å; W387-V409 HydrophobicContact CG-CB 4.46Å; W387-V409 HydrophobicContact CG-CG1 4.02Å; W387-E413 WeakPolarHBondContact CZ2-OE1 3.41Å; W387-E413 PolarHBondContact NE1-OE2 3.34Å; W387-M420 HydrophobicContact CH2-SD 4.01Å; W387-P421 HydrophobicContact CH2-CG 4.22Å; W387-P421 HydrophobicContact CZ2-CG 3.79Å
388S87Confident70.2Confident7 Ų762.5 Ų62.55%0.04934%0.339CS..  trans-93.3137.1-175-64.40000111P384 V385 W405P384-S388 PolarHBondContact O-N 2.95Å; P384-S388 PolarHBondContact O-OG 2.92Å; V385-S388 PolarHBondContact O-N 2.66Å; V385-S388 VanDerWaalsContact O-N 3.08Å; S388-W405 PolarHBondContact O-NE1 3.19Å
389P91.1Very high72.1Confident3 Ų360.1 Ų60.12%0.01932%0.322CS..  trans-74165.917334.8-41.3000112.4E391 V392 L393 W405P389-E391 VanDerWaalsContact C-N 3.31Å; P389-E391 WeakPolarHBondContact CB-OE1 3.32Å; P389-E391 WeakPolarHBondContact CB-OE2 3.18Å; P389-E391 HydrophobicContact CG-CG 4.43Å; P389-E391 WeakPolarHBondContact CG-OE1 3.45Å; P389-E391 PolarHBondContact O-N 3.14Å; P389-V392 HydrophobicContact CG-CB 3.85Å; P389-V392 HydrophobicContact CG-CG2 3.54Å; P389-V392 PolarHBondContact O-N 2.94Å; P389-V392 VanDerWaalsContact O-N 3.07Å; P389-L393 WeakPolarHBondContact O-CG 3.47Å; P389-L393 PolarHBondContact O-N 2.92Å; P389-W405 HydrophobicContact CB-CB 3.82Å; P389-W405 HydrophobicContact CB-CD2 3.48Å; P389-W405 VanDerWaalsContact CB-CD2 3.48Å; P389-W405 HydrophobicContact CB-CE3 3.64Å; P389-W405 HydrophobicContact CB-CG 3.56Å; P389-W405 HydrophobicContact CB-CZ3 4.38Å; P389-W405 HydrophobicContact CG-CB 4.25Å; P389-W405 HydrophobicContact CG-CG 4.32Å
390P89.8Confident74.4Confident14 Ų1455.2 Ų55.29%0.09130%0.295CS..Hα-helixtrans-51.1-44180-23.628.7000114.1V392 L393 M394 W405 I434P390-V392 VanDerWaalsContact C-N 3.3Å; P390-V392 PolarHBondContact O-N 2.67Å; P390-L393 PolarHBondContact O-N 3.32Å; P390-M394 WeakPolarHBondContact O-CB 3.22Å; P390-M394 WeakPolarHBondContact O-CG 3.17Å; P390-M394 PolarHBondContact O-N 3.25Å; P390-W405 HydrophobicContact CG-CH2 4.13Å; P390-W405 HydrophobicContact CG-CZ3 4.27Å; P390-I434 HydrophobicContact CG-CG2 3.81Å
391E84.8Confident76.9Confident22 Ų2253.3 Ų53.310%0.10326%0.263CS..Hα-helixtrans-68.4-28-177.871-78.8-177.500113.5P389 Y395 S396 K397 R465P389-E391 VanDerWaalsContact C-N 3.31Å; P389-E391 WeakPolarHBondContact CB-OE1 3.32Å; P389-E391 WeakPolarHBondContact CB-OE2 3.18Å; P389-E391 HydrophobicContact CG-CG 4.43Å; P389-E391 WeakPolarHBondContact CG-OE1 3.45Å; P389-E391 PolarHBondContact O-N 3.14Å; E391-Y395 HydrophobicContact CB-CD2 4.45Å; E391-Y395 CarbonylContact O-C 3.54Å; E391-Y395 WeakPolarHBondContact O-CA 3.4Å; E391-Y395 WeakPolarHBondContact O-CB 3.31Å; E391-Y395 PolarHBondContact O-N 3.26Å; E391-S396 PolarHBondContact O-N 2.94Å; E391-K397 HydrophobicContact CB-CB 4.37Å; E391-K397 HydrophobicContact CG-CB 4.34Å; E391-K397 PolarHBondContact O-N 3.15Å; E391-R465 IonicContact OE1-CZ 2.72Å; E391-R465 IonicContact OE1-NH1 3.92Å; E391-R465 PolarHBondContact OE1-NH1 3.31Å; E391-R465 IonicContact OE1-NH2 3.47Å; E391-R465 PolarHBondContact OE1-NH2 3.24Å; E391-R465 IonicContact OE2-CZ 3.5Å; E391-R465 IonicContact OE2-NH1 2.99Å; E391-R465 IonicContact OE2-NH2 3.2Å; E391-R465 PolarHBondContact OE2-NH2 2.93Å
392V84.4Confident79Confident1 Ų150.8 Ų50.81%0.00625%0.246CC..Hα-helixtrans-75.6-40.4173169.50000110.3F383 P389 P390 S396 K397 F398F383-V392 HydrophobicContact CE2-CG1 4.11Å; F383-V392 HydrophobicContact CZ-CG1 3.83Å; P389-V392 HydrophobicContact CG-CB 3.85Å; P389-V392 HydrophobicContact CG-CG2 3.54Å; P389-V392 PolarHBondContact O-N 2.94Å; P389-V392 VanDerWaalsContact O-N 3.07Å; P390-V392 VanDerWaalsContact C-N 3.3Å; P390-V392 PolarHBondContact O-N 2.67Å; V392-S396 VanDerWaalsContact O-CA 3.23Å; V392-S396 WeakPolarHBondContact O-CA 3.42Å; V392-S396 PolarHBondContact O-N 3.46Å; V392-K397 WeakPolarHBondContact CG2-O 3.19Å; V392-F398 HydrophobicContact CG1-CD1 3.93Å; V392-F398 HydrophobicContact CG1-CD2 4.19Å; V392-F398 HydrophobicContact CG1-CE1 3.51Å; V392-F398 HydrophobicContact CG1-CE2 3.83Å; V392-F398 HydrophobicContact CG1-CG 4.28Å; V392-F398 HydrophobicContact CG1-CZ 3.49Å; V392-F398 VanDerWaalsContact CG1-CZ 3.49Å; V392-F398 HydrophobicContact CG2-CB 4.37Å; V392-F398 HydrophobicContact CG2-CD1 3.88Å; V392-F398 HydrophobicContact CG2-CD2 4.27Å; V392-F398 HydrophobicContact CG2-CE1 4.33Å; V392-F398 HydrophobicContact CG2-CG 3.88Å
393L80.8Confident80.5Confident39 Ų3943.6 Ų43.620%0.20422%0.218CC..Hα-helixtrans-66.7-42.1179.7-65.5175.2000112.5F383 V385 P389 P390 A431 I434F383-L393 HydrophobicContact CE1-CD2 3.65Å; F383-L393 HydrophobicContact CZ-CD2 4.1Å; V385-L393 HydrophobicContact CB-CD2 4.46Å; V385-L393 HydrophobicContact CG1-CD2 3.9Å; P389-L393 WeakPolarHBondContact O-CG 3.47Å; P389-L393 PolarHBondContact O-N 2.92Å; P390-L393 PolarHBondContact O-N 3.32Å; L393-A431 HydrophobicContact CD1-CB 3.94Å; L393-A431 HydrophobicContact CD2-CB 4.39Å; L393-I434 HydrophobicContact CD1-CD1 4.5Å; L393-I434 HydrophobicContact CD1-CG2 4.25Å
394M75.1Confident81.6Confident100 Ų10040.5 Ų40.549%0.49320%0.204SC..Hα-helixtrans-87.1-43-176-65.1-175.8-175.500113.1P390 A435P390-M394 WeakPolarHBondContact O-CB 3.22Å; P390-M394 WeakPolarHBondContact O-CG 3.17Å; P390-M394 PolarHBondContact O-N 3.25Å; M394-A435 HydrophobicContact CE-CB 3.14Å
395Y74.1Confident82.4Confident175 Ų17538 Ų3869%0.68619%0.188SC*.Hα-helixtrans-120.7-0.3-166.7-48.2-64000113E391 K397E391-Y395 HydrophobicContact CB-CD2 4.45Å; E391-Y395 CarbonylContact O-C 3.54Å; E391-Y395 WeakPolarHBondContact O-CA 3.4Å; E391-Y395 WeakPolarHBondContact O-CB 3.31Å; E391-Y395 PolarHBondContact O-N 3.26Å; Y395-K397 PolarHBondContact O-N 2.77Å
396S69.1Low82.8Confident59 Ų5938.5 Ų38.541%0.41319%0.194SC..  trans52.235.5-173.5-61.60000112.6E391 V392 F398E391-S396 PolarHBondContact O-N 2.94Å; V392-S396 VanDerWaalsContact O-CA 3.23Å; V392-S396 WeakPolarHBondContact O-CA 3.42Å; V392-S396 PolarHBondContact O-N 3.46Å; S396-F398 WeakPolarHBondContact O-CD2 3.35Å; S396-F398 PolarHBondContact O-N 2.69Å
397K71.7Confident83Confident89 Ų8938.8 Ų38.839%0.38720%0.197SC..  trans-91.695.8178.8178.5170.6171.6146.50110.1E374 E391 V392 Y395E374-K397 HydrophobicContact CG-CD 4.33Å; E374-K397 HydrophobicContact CG-CG 3.89Å; E374-K397 WeakPolarHBondContact OE1-CD 3.35Å; E374-K397 WeakPolarHBondContact OE1-CE 3.49Å; E374-K397 IonicContact OE1-NZ 2.7Å; E374-K397 PolarHBondContact OE1-NZ 2.83Å; E391-K397 HydrophobicContact CB-CB 4.37Å; E391-K397 HydrophobicContact CG-CB 4.34Å; E391-K397 PolarHBondContact O-N 3.15Å; V392-K397 WeakPolarHBondContact CG2-O 3.19Å; Y395-K397 PolarHBondContact O-N 2.77Å
398F75.1Confident83.1Confident21 Ų2137.4 Ų37.49%0.09219%0.191CC..BIsolated β-bridgetrans-100.1128.1-179.5-63.8-109.1000111.9D373 E374 Y375 F383 V392 S396D373-F398 CarbonylContact C-O 3.43Å; D373-F398 CarbonylContact O-C 3.59Å; E374-F398 CarbonylContact C-O 3.53Å; E374-F398 WeakPolarHBondContact CA-O 3.4Å; E374-F398 PolarHBondContact N-O 3.32Å; Y375-F398 HydrophobicContact CD1-CB 3.4Å; Y375-F398 VanDerWaalsContact CD1-CB 3.4Å; Y375-F398 HydrophobicContact CD1-CG 4.45Å; Y375-F398 WeakPolarHBondContact CD1-O 3.43Å; Y375-F398 HydrophobicContact CD2-CB 3.6Å; Y375-F398 HydrophobicContact CD2-CD1 4.13Å; Y375-F398 HydrophobicContact CD2-CD2 4.29Å; Y375-F398 AromaticContact CD2-CG 3.8Å; Y375-F398 HydrophobicContact CD2-CG 3.8Å; Y375-F398 HydrophobicContact CE1-CB 3.3Å; Y375-F398 HydrophobicContact CE1-CD1 4.36Å; Y375-F398 HydrophobicContact CE1-CG 4.22Å; Y375-F398 HydrophobicContact CE2-CB 3.48Å; Y375-F398 VanDerWaalsContact CE2-CB 3.48Å; Y375-F398 AromaticContact CE2-CD1 3.38Å; Y375-F398 HydrophobicContact CE2-CD1 3.38Å; Y375-F398 HydrophobicContact CE2-CD2 4.33Å; Y375-F398 HydrophobicContact CE2-CE1 4.05Å; Y375-F398 AromaticContact CE2-CG 3.51Å; Y375-F398 HydrophobicContact CE2-CG 3.51Å; Y375-F398 HydrophobicContact CG-CB 3.55Å; Y375-F398 HydrophobicContact CG-CG 4.25Å; Y375-F398 AromaticContact CZ-CD1 3.51Å; Y375-F398 AromaticContact CZ-CG 3.74Å; Y375-F398 PolarHBondContact N-O 3.49Å; Y375-F398 WeakPolarHBondContact O-CB 3.48Å; Y375-F398 WeakPolarHBondContact O-CD2 3.36Å; Y375-F398 WeakPolarHBondContact OH-CD1 3.39Å; F383-F398 AromaticContact CE2-CZ 3.89Å; F383-F398 HydrophobicContact CE2-CZ 3.89Å; V392-F398 HydrophobicContact CG1-CD1 3.93Å; V392-F398 HydrophobicContact CG1-CD2 4.19Å; V392-F398 HydrophobicContact CG1-CE1 3.51Å; V392-F398 HydrophobicContact CG1-CE2 3.83Å; V392-F398 HydrophobicContact CG1-CG 4.28Å; V392-F398 HydrophobicContact CG1-CZ 3.49Å; V392-F398 VanDerWaalsContact CG1-CZ 3.49Å; V392-F398 HydrophobicContact CG2-CB 4.37Å; V392-F398 HydrophobicContact CG2-CD1 3.88Å; V392-F398 HydrophobicContact CG2-CD2 4.27Å; V392-F398 HydrophobicContact CG2-CE1 4.33Å; V392-F398 HydrophobicContact CG2-CG 3.88Å; S396-F398 WeakPolarHBondContact O-CD2 3.35Å; S396-F398 PolarHBondContact O-N 2.69Å
399S76.1Confident83.5Confident10 Ų1037 Ų377%0.0719%0.189CC..  trans-138.4176.7-177.369.80000111.9D373 K401 S402 D403D373-S399 WeakPolarHBondContact O-CA 2.89Å; D373-S399 WeakPolarHBondContact O-CB 3.12Å; S399-K401 PolarHBondContact O-N 2.83Å; S399-K401 VanDerWaalsContact O-N 3.14Å; S399-K401 WeakPolarHBondContact OG-CB 3.46Å; S399-K401 PolarHBondContact OG-N 2.85Å; S399-S402 PolarHBondContact N-OG 3.36Å; S399-S402 WeakPolarHBondContact O-CB 3.18Å; S399-S402 PolarHBondContact O-N 2.87Å; S399-S402 PolarHBondContact O-OG 3.23Å; S399-S402 PolarHBondContact OG-N 3.07Å; S399-D403 PolarHBondContact O-N 2.84Å
400S77.1Confident83.4Confident56 Ų5639.3 Ų39.339%0.39220%0.201SC..Hα-helixtrans-50.5-34.1165.257.30000112.4D373 D403 I404D373-S400 PolarHBondContact OD1-OG 3.32Å; S400-D403 PolarHBondContact O-N 3.11Å; S400-I404 WeakPolarHBondContact O-CG1 3.44Å; S400-I404 PolarHBondContact O-N 3.48Å; S400-I404 VanDerWaalsContact O-N 3.15Å
401K87.4Confident83.5Confident42 Ų4239.3 Ų39.318%0.18320%0.2CC..Hα-helixtrans-74.7-23.6177.6-54.1-62.3-165.1160.40113.7S399 W405 A462 D463 R465S399-K401 PolarHBondContact O-N 2.83Å; S399-K401 VanDerWaalsContact O-N 3.14Å; S399-K401 WeakPolarHBondContact OG-CB 3.46Å; S399-K401 PolarHBondContact OG-N 2.85Å; K401-W405 PolarHBondContact O-N 3.05Å; K401-A462 HydrophobicContact CB-CB 3.89Å; K401-A462 WeakPolarHBondContact CB-O 3.45Å; K401-A462 WeakPolarHBondContact CD-O 3.34Å; K401-A462 HydrophobicContact CG-CB 4.32Å; K401-A462 WeakPolarHBondContact CG-O 3.5Å; K401-D463 PolarHBondContact NZ-O 2.74Å; K401-R465 HydrophobicContact CD-CB 4.37Å; K401-R465 PolarHBondContact NZ-O 3.49Å; K401-R465 PolarHBondContact O-NH1 2.86Å
402S83.6Confident83.9Confident4 Ų438.3 Ų38.33%0.02820%0.195CC..Hα-helixtrans-73.4-33.6170.7720000112S399 I404 W405 A406S399-S402 PolarHBondContact N-OG 3.36Å; S399-S402 WeakPolarHBondContact O-CB 3.18Å; S399-S402 PolarHBondContact O-N 2.87Å; S399-S402 PolarHBondContact O-OG 3.23Å; S399-S402 PolarHBondContact OG-N 3.07Å; S402-I404 VanDerWaalsContact C-N 3.33Å; S402-W405 WeakPolarHBondContact O-CB 3.23Å; S402-W405 PolarHBondContact O-N 2.9Å; S402-A406 PolarHBondContact O-N 3.27Å; S402-A406 VanDerWaalsContact O-N 3.13Å
403D83.4Confident84.2Confident60 Ų6040 Ų4032%0.32120%0.203SC..Hα-helixtrans-68.3-35.6172.9-63.2-22.1000111.1Y375 S399 S400 A406 F407 F468Y375-D403 PolarHBondContact OH-OD1 2.95Å; S399-D403 PolarHBondContact O-N 2.84Å; S400-D403 PolarHBondContact O-N 3.11Å; D403-A406 PolarHBondContact O-N 3.05Å; D403-F407 WeakPolarHBondContact O-CB 3.46Å; D403-F407 PolarHBondContact O-N 3.15Å; D403-F468 HydrophobicContact CB-CE2 4.15Å; D403-F468 HydrophobicContact CB-CZ 4.29Å
404I88Confident84.5Confident2 Ų243.2 Ų43.21%0.0122%0.219CC..Hα-helixtrans-59.5-45.5172.5-65.2-70.9000111.1S400 S402 A406 F407 G408 C457 R465 P466 F468 L471S400-I404 WeakPolarHBondContact O-CG1 3.44Å; S400-I404 PolarHBondContact O-N 3.48Å; S400-I404 VanDerWaalsContact O-N 3.15Å; S402-I404 VanDerWaalsContact C-N 3.33Å; I404-A406 PolarHBondContact O-N 3.25Å; I404-F407 WeakPolarHBondContact O-CB 3.08Å; I404-F407 PolarHBondContact O-N 3.21Å; I404-G408 PolarHBondContact O-N 3.39Å; I404-C457 HydrophobicContact CG2-CB 3.89Å; I404-C457 WeakPolarHBondContact O-CB 3.44Å; I404-R465 HydrophobicContact CG2-CB 4Å; I404-P466 WeakPolarHBondContact CD1-O 3.35Å; I404-P466 WeakPolarHBondContact CG1-O 3.23Å; I404-P466 HydrophobicContact CG2-CG 4.33Å; I404-F468 HydrophobicContact CD1-CB 4.44Å; I404-F468 HydrophobicContact CD1-CD1 3.88Å; I404-F468 HydrophobicContact CD1-CD2 3.64Å; I404-F468 HydrophobicContact CD1-CE1 3.96Å; I404-F468 HydrophobicContact CD1-CE2 3.71Å; I404-F468 HydrophobicContact CD1-CG 3.71Å; I404-F468 HydrophobicContact CD1-CZ 3.87Å; I404-F468 HydrophobicContact CG1-CE2 4.28Å; I404-L471 HydrophobicContact CD1-CD1 3.64Å; I404-L471 HydrophobicContact CG2-CD1 4.24Å
405W93.6Very high85.2Confident0 Ų042.1 Ų42.10%021%0.21CC..Hα-helixtrans-58.1-49.2175.6-179.5-73000111.7S388 P389 P390 K401 S402 F407 G408 V409 I434 W458S388-W405 PolarHBondContact O-NE1 3.19Å; P389-W405 HydrophobicContact CB-CB 3.82Å; P389-W405 HydrophobicContact CB-CD2 3.48Å; P389-W405 VanDerWaalsContact CB-CD2 3.48Å; P389-W405 HydrophobicContact CB-CE3 3.64Å; P389-W405 HydrophobicContact CB-CG 3.56Å; P389-W405 HydrophobicContact CB-CZ3 4.38Å; P389-W405 HydrophobicContact CG-CB 4.25Å; P389-W405 HydrophobicContact CG-CG 4.32Å; P390-W405 HydrophobicContact CG-CH2 4.13Å; P390-W405 HydrophobicContact CG-CZ3 4.27Å; K401-W405 PolarHBondContact O-N 3.05Å; S402-W405 WeakPolarHBondContact O-CB 3.23Å; S402-W405 PolarHBondContact O-N 2.9Å; W405-F407 VanDerWaalsContact C-N 3.26Å; W405-F407 PolarHBondContact O-N 3.45Å; W405-G408 PolarHBondContact O-N 3.3Å; W405-G408 VanDerWaalsContact O-N 3.13Å; W405-V409 PolarHBondContact O-N 3.3Å; W405-V409 VanDerWaalsContact O-N 3.12Å; W405-I434 HydrophobicContact CH2-CG2 3.84Å; W405-I434 HydrophobicContact CZ2-CG2 3.62Å; W405-W458 HydrophobicContact CD2-CB 4.4Å; W405-W458 AromaticContact CD2-CD1 3.57Å; W405-W458 HydrophobicContact CD2-CG 4.33Å; W405-W458 AromaticContact CE2-CD1 3.7Å; W405-W458 HydrophobicContact CE3-CB 4.01Å; W405-W458 AromaticContact CE3-CD1 3.99Å; W405-W458 HydrophobicContact CE3-CG 4.41Å; W405-W458 AromaticContact CG-CD1 3.82Å; W405-W458 HydrophobicContact CH2-CB 3.99Å; W405-W458 HydrophobicContact CZ2-CB 4.38Å; W405-W458 HydrophobicContact CZ2-CG 4.45Å; W405-W458 HydrophobicContact CZ3-CB 3.8Å; W405-W458 WeakPolarHBondContact CZ3-O 3.49Å; W405-W458 AromaticContact NE1-CD1 4Å; W405-W458 PolarHBondContact O-NE1 2.83Å
406A89.8Confident85.9Confident30 Ų3034.3 Ų34.325%0.24818%0.181CC..Hα-helixtrans-61.3-36.3178.800000111.9W387 S402 D403 I404 V409 L410W387-A406 HydrophobicContact CB-CB 4.47Å; S402-A406 PolarHBondContact O-N 3.27Å; S402-A406 VanDerWaalsContact O-N 3.13Å; D403-A406 PolarHBondContact O-N 3.05Å; I404-A406 PolarHBondContact O-N 3.25Å; A406-V409 PolarHBondContact O-N 3.44Å; A406-L410 PolarHBondContact O-N 2.86Å
407F89.8Confident86.7Confident51 Ų5137.5 Ų37.522%0.22419%0.193CC..Hα-helixtrans-63.4-41.6173.5178.2-99.8000112.3D403 I404 W405 V409 L410 M411 F468 L471 I475D403-F407 WeakPolarHBondContact O-CB 3.46Å; D403-F407 PolarHBondContact O-N 3.15Å; I404-F407 WeakPolarHBondContact O-CB 3.08Å; I404-F407 PolarHBondContact O-N 3.21Å; W405-F407 VanDerWaalsContact C-N 3.26Å; W405-F407 PolarHBondContact O-N 3.45Å; F407-V409 VanDerWaalsContact C-N 3.3Å; F407-V409 PolarHBondContact O-N 3.1Å; F407-L410 HydrophobicContact CD2-CD2 4.42Å; F407-L410 WeakPolarHBondContact O-CB 3.42Å; F407-L410 PolarHBondContact O-N 3.11Å; F407-L410 VanDerWaalsContact O-N 3.13Å; F407-M411 HydrophobicContact CD1-CG 4.2Å; F407-M411 HydrophobicContact CD1-SD 4.04Å; F407-M411 HydrophobicContact CE1-CG 3.77Å; F407-M411 HydrophobicContact CE1-SD 3.4Å; F407-M411 WeakPolarHBondContact CE1-SD 3.44Å; F407-M411 HydrophobicContact CE2-CG 4.49Å; F407-M411 HydrophobicContact CZ-CG 3.93Å; F407-M411 HydrophobicContact CZ-SD 3.98Å; F407-M411 WeakPolarHBondContact O-CG 3.31Å; F407-M411 PolarHBondContact O-N 3.25Å; F407-F468 HydrophobicContact CB-CE1 3.77Å; F407-F468 HydrophobicContact CB-CZ 4.1Å; F407-F468 HydrophobicContact CD1-CE1 4.21Å; F407-F468 AromaticContact CD2-CE1 3.92Å; F407-F468 HydrophobicContact CD2-CE1 3.92Å; F407-F468 AromaticContact CG-CE1 3.7Å; F407-F468 HydrophobicContact CG-CE1 3.7Å; F407-F468 HydrophobicContact CG-CZ 4.49Å; F407-L471 HydrophobicContact CD1-CD1 3.67Å; F407-L471 HydrophobicContact CE1-CB 4.49Å; F407-L471 HydrophobicContact CE1-CD1 3.89Å; F407-I475 HydrophobicContact CE1-CD1 4.28Å; F407-I475 HydrophobicContact CZ-CD1 3.98Å
408G93.6Very high87.2Confident0 Ų034.3 Ų34.30%019%0.186CC..Hα-helixtrans-57.8-43.7172.200000112I404 W405 L410 M411 W412 W458I404-G408 PolarHBondContact O-N 3.39Å; W405-G408 PolarHBondContact O-N 3.3Å; W405-G408 VanDerWaalsContact O-N 3.13Å; G408-L410 VanDerWaalsContact C-N 3.34Å; G408-L410 PolarHBondContact O-N 2.87Å; G408-M411 WeakPolarHBondContact O-CB 3.49Å; G408-M411 PolarHBondContact O-N 3.36Å; G408-W412 PolarHBondContact O-N 3.46Å; G408-W458 VanDerWaalsContact O-CZ2 3.25Å; G408-W458 WeakPolarHBondContact O-CZ2 3.17Å
409V94.2Very high87.7Confident0 Ų036.7 Ų36.70%020%0.196CC..Hα-helixtrans-63.8-39.4175.3-177.90000111.2W387 W405 A406 F407 W412 E413 P421 L440 W458W387-V409 VanDerWaalsContact CD1-CG1 3.46Å; W387-V409 HydrophobicContact CD2-CG1 4.41Å; W387-V409 HydrophobicContact CG-CB 4.46Å; W387-V409 HydrophobicContact CG-CG1 4.02Å; W405-V409 PolarHBondContact O-N 3.3Å; W405-V409 VanDerWaalsContact O-N 3.12Å; A406-V409 PolarHBondContact O-N 3.44Å; F407-V409 VanDerWaalsContact C-N 3.3Å; F407-V409 PolarHBondContact O-N 3.1Å; V409-W412 WeakPolarHBondContact O-CB 3.41Å; V409-W412 PolarHBondContact O-N 2.73Å; V409-E413 WeakPolarHBondContact O-CG 3.48Å; V409-E413 PolarHBondContact O-N 3.35Å; V409-P421 HydrophobicContact CG1-CB 3.91Å; V409-P421 HydrophobicContact CG1-CG 3.54Å; V409-L440 HydrophobicContact CG1-CD1 4.17Å; V409-L440 HydrophobicContact CG2-CD1 4.24Å; V409-W458 HydrophobicContact CG2-CZ2 4.21Å
410L91Very high88.2Confident51 Ų5140.4 Ų40.427%0.26721%0.213SC..Hα-helixtrans-62.5-43.6174.7176.765.2000112.1A406 F407 G408 W412 E413 I414A406-L410 PolarHBondContact O-N 2.86Å; F407-L410 HydrophobicContact CD2-CD2 4.42Å; F407-L410 WeakPolarHBondContact O-CB 3.42Å; F407-L410 PolarHBondContact O-N 3.11Å; F407-L410 VanDerWaalsContact O-N 3.13Å; G408-L410 VanDerWaalsContact C-N 3.34Å; G408-L410 PolarHBondContact O-N 2.87Å; L410-W412 VanDerWaalsContact C-N 3.28Å; L410-W412 PolarHBondContact O-N 2.81Å; L410-E413 WeakPolarHBondContact O-CB 3.4Å; L410-E413 PolarHBondContact O-N 2.79Å; L410-I414 HydrophobicContact CD1-CD1 4.49Å; L410-I414 HydrophobicContact CG-CD1 4.19Å; L410-I414 WeakPolarHBondContact O-CG1 3.34Å; L410-I414 PolarHBondContact O-N 3.38Å
411M90.3Very high88.8Confident14 Ų1437.8 Ų37.87%0.06920%0.195CC..Hα-helixtrans-57.8-45.5173.1-69.8-175.274.700110.4F407 G408 E413 I414 Y415 I453 M454F407-M411 HydrophobicContact CD1-CG 4.2Å; F407-M411 HydrophobicContact CD1-SD 4.04Å; F407-M411 HydrophobicContact CE1-CG 3.77Å; F407-M411 HydrophobicContact CE1-SD 3.4Å; F407-M411 WeakPolarHBondContact CE1-SD 3.44Å; F407-M411 HydrophobicContact CE2-CG 4.49Å; F407-M411 HydrophobicContact CZ-CG 3.93Å; F407-M411 HydrophobicContact CZ-SD 3.98Å; F407-M411 WeakPolarHBondContact O-CG 3.31Å; F407-M411 PolarHBondContact O-N 3.25Å; G408-M411 WeakPolarHBondContact O-CB 3.49Å; G408-M411 PolarHBondContact O-N 3.36Å; M411-E413 VanDerWaalsContact C-N 3.31Å; M411-E413 PolarHBondContact O-N 3.27Å; M411-I414 PolarHBondContact O-N 2.91Å; M411-Y415 WeakPolarHBondContact O-CD2 3.31Å; M411-Y415 PolarHBondContact O-N 2.67Å; M411-I453 HydrophobicContact CE-CB 4.28Å; M411-I453 HydrophobicContact CE-CG2 3.86Å; M411-I453 HydrophobicContact SD-CG2 4Å; M411-M454 HydrophobicContact CB-CB 3.88Å; M411-M454 HydrophobicContact CB-CE 4.44Å; M411-M454 HydrophobicContact CE-CB 4.46Å; M411-M454 HydrophobicContact SD-CB 4.02Å
412W94.6Very high88.9Confident1 Ų136.4 Ų36.40%0.00419%0.188CC..Hα-helixtrans-59.6-41.7176.3-175.994.3000112.3G408 V409 L410 Y415 S416 K419 P421 L440 Y441 P443 M454 W458G408-W412 PolarHBondContact O-N 3.46Å; V409-W412 WeakPolarHBondContact O-CB 3.41Å; V409-W412 PolarHBondContact O-N 2.73Å; L410-W412 VanDerWaalsContact C-N 3.28Å; L410-W412 PolarHBondContact O-N 2.81Å; W412-Y415 PolarHBondContact O-N 2.84Å; W412-S416 VanDerWaalsContact CE2-OG 3.31Å; W412-S416 WeakPolarHBondContact CZ2-OG 3.24Å; W412-S416 WeakPolarHBondContact O-CB 3.33Å; W412-S416 PolarHBondContact O-N 2.96Å; W412-S416 PolarHBondContact O-OG 3.34Å; W412-K419 HydrophobicContact CH2-CB 3.91Å; W412-K419 HydrophobicContact CZ3-CB 4.07Å; W412-P421 HydrophobicContact CE3-CB 4.41Å; W412-P421 HydrophobicContact CE3-CG 4.19Å; W412-P421 HydrophobicContact CZ3-CB 4.27Å; W412-P421 HydrophobicContact CZ3-CG 4.14Å; W412-L440 HydrophobicContact CB-CD1 4.01Å; W412-L440 HydrophobicContact CD2-CB 4.36Å; W412-L440 HydrophobicContact CD2-CD1 3.83Å; W412-L440 HydrophobicContact CD2-CD2 4.31Å; W412-L440 HydrophobicContact CD2-CG 4.39Å; W412-L440 HydrophobicContact CE3-CD1 4.21Å; W412-L440 HydrophobicContact CG-CB 4.07Å; W412-L440 HydrophobicContact CG-CD1 3.71Å; W412-L440 HydrophobicContact CG-CG 4.39Å; W412-L440 HydrophobicContact CZ2-CD2 4.26Å; W412-Y441 VanDerWaalsContact CD1-O 3.28Å; W412-Y441 HydrophobicContact CZ2-CD1 4.45Å; W412-Y441 AromaticContact CZ2-CE1 3.75Å; W412-Y441 HydrophobicContact CZ2-CE1 3.75Å; W412-Y441 HydrophobicContact CZ2-CE2 4.38Å; W412-Y441 AromaticContact CZ2-CZ 3.7Å; W412-Y441 PolarHBondContact NE1-O 3.28Å; W412-P443 VanDerWaalsContact CD1-CG 3.48Å; W412-P443 HydrophobicContact CG-CG 4.1Å; W412-M454 HydrophobicContact CB-SD 4.05Å; W412-W458 HydrophobicContact CB-CH2 4Å; W412-W458 HydrophobicContact CB-CZ2 4.13Å; W412-W458 HydrophobicContact CG-CH2 4.35Å
413E89.9Confident89.1Confident36 Ų3641.3 Ų41.317%0.16821%0.211CC..Hα-helixtrans-61.2-45.4175.1-74-17897.900111.7W387 V409 L410 M411 S416 L417 G418 P421W387-E413 WeakPolarHBondContact CZ2-OE1 3.41Å; W387-E413 PolarHBondContact NE1-OE2 3.34Å; V409-E413 WeakPolarHBondContact O-CG 3.48Å; V409-E413 PolarHBondContact O-N 3.35Å; L410-E413 WeakPolarHBondContact O-CB 3.4Å; L410-E413 PolarHBondContact O-N 2.79Å; M411-E413 VanDerWaalsContact C-N 3.31Å; M411-E413 PolarHBondContact O-N 3.27Å; E413-S416 CarbonylContact O-C 3.58Å; E413-S416 PolarHBondContact O-N 2.87Å; E413-L417 PolarHBondContact O-N 3.09Å; E413-L417 VanDerWaalsContact O-N 3.1Å; E413-G418 WeakPolarHBondContact O-CA 3.08Å; E413-G418 PolarHBondContact O-N 3.5Å; E413-P421 HydrophobicContact CG-CG 3.89Å
414I86.8Confident89.5Confident106 Ų10648.9 Ų48.954%0.54424%0.235SC..Hα-helixtrans-57.4-53.3177.7-68.8164.9000109.9L410 M411 S416 L417L410-I414 HydrophobicContact CD1-CD1 4.49Å; L410-I414 HydrophobicContact CG-CD1 4.19Å; L410-I414 WeakPolarHBondContact O-CG1 3.34Å; L410-I414 PolarHBondContact O-N 3.38Å; M411-I414 PolarHBondContact O-N 2.91Å; I414-S416 PolarHBondContact O-N 2.84Å; I414-L417 PolarHBondContact O-N 3.29Å; I414-L417 VanDerWaalsContact O-N 3.1Å
415Y89.8Confident89.4Confident77 Ų7751.7 Ų51.730%0.30225%0.247SC..Hα-helixtrans-72.6-11.2-179-79.9-83.6000114.1M411 W412 P443 L445 A446 V450 M454M411-Y415 WeakPolarHBondContact O-CD2 3.31Å; M411-Y415 PolarHBondContact O-N 2.67Å; W412-Y415 PolarHBondContact O-N 2.84Å; Y415-P443 WeakPolarHBondContact O-CB 3.26Å; Y415-L445 HydrophobicContact CD1-CB 4.26Å; Y415-L445 WeakPolarHBondContact CD1-O 3.33Å; Y415-A446 HydrophobicContact CD1-CB 3.81Å; Y415-A446 HydrophobicContact CE1-CB 4.48Å; Y415-A446 HydrophobicContact CG-CB 3.93Å; Y415-V450 HydrophobicContact CD1-CG1 4.29Å; Y415-V450 HydrophobicContact CD2-CG1 3.84Å; Y415-V450 HydrophobicContact CE1-CG1 3.83Å; Y415-V450 HydrophobicContact CE2-CG1 3.35Å; Y415-V450 HydrophobicContact CG-CG1 4.29Å; Y415-M454 HydrophobicContact CD2-CE 4.04Å; Y415-M454 HydrophobicContact CG-CE 4.37Å
416S88.3Confident88.8Confident12 Ų1255.2 Ų55.28%0.08427%0.269CS..THydrogen-bonded Turntrans-103.111.4173-54.60000112.9W412 E413 I414 G418 K419 P443W412-S416 VanDerWaalsContact CE2-OG 3.31Å; W412-S416 WeakPolarHBondContact CZ2-OG 3.24Å; W412-S416 WeakPolarHBondContact O-CB 3.33Å; W412-S416 PolarHBondContact O-N 2.96Å; W412-S416 PolarHBondContact O-OG 3.34Å; E413-S416 CarbonylContact O-C 3.58Å; E413-S416 PolarHBondContact O-N 2.87Å; I414-S416 PolarHBondContact O-N 2.84Å; S416-G418 PolarHBondContact O-N 2.71Å; S416-K419 WeakPolarHBondContact O-CG 3.41Å; S416-K419 PolarHBondContact O-N 3.42Å; S416-P443 WeakPolarHBondContact OG-CB 3.27Å; S416-P443 VanDerWaalsContact OG-CG 3.3Å; S416-P443 WeakPolarHBondContact OG-CG 3.35Å
417L87.3Confident88.2Confident125 Ų12557 Ų5765%0.65427%0.274SS*.THydrogen-bonded Turntrans55.240-179.1-51.8179.5000112.8R332 E413 I414 L445R332-L417 PolarHBondContact NH2-O 3.26Å; E413-L417 PolarHBondContact O-N 3.09Å; E413-L417 VanDerWaalsContact O-N 3.1Å; I414-L417 PolarHBondContact O-N 3.29Å; I414-L417 VanDerWaalsContact O-N 3.1Å; L417-L445 HydrophobicContact CD1-CD1 4.07Å; L417-L445 HydrophobicContact CD2-CD1 3.87Å; L417-L445 HydrophobicContact CG-CD1 3.9Å
418G82Confident87.6Confident23 Ų2359.3 Ų59.324%0.23730%0.297CS..THydrogen-bonded Turntrans73.427.3176.300000114.6R332 E413 S416R332-G418 VanDerWaalsContact CZ-O 3.31Å; R332-G418 PolarHBondContact NH1-O 3.2Å; R332-G418 PolarHBondContact NH2-O 3.32Å; E413-G418 WeakPolarHBondContact O-CA 3.08Å; E413-G418 PolarHBondContact O-N 3.5Å; S416-G418 PolarHBondContact O-N 2.71Å
419K84.9Confident87.2Confident71 Ų7163.3 Ų63.331%0.30932%0.315SS..PPolyproline II helixtrans-58.6154.4167.9-79.3-177.8-177.1-170.60111.1W412 S416 P421W412-K419 HydrophobicContact CH2-CB 3.91Å; W412-K419 HydrophobicContact CZ3-CB 4.07Å; S416-K419 WeakPolarHBondContact O-CG 3.41Å; S416-K419 PolarHBondContact O-N 3.42Å; K419-P421 WeakPolarHBondContact O-CD 3.35Å
420M86Confident86.8Confident88 Ų8863.3 Ų63.343%0.43332%0.315SS..PPolyproline II helixtrans-71.4124.7174.5-175.569.861.200109.4W387 Y422 E423W387-M420 HydrophobicContact CH2-SD 4.01Å; M420-Y422 PolarHBondContact O-N 2.9Å; M420-E423 HydrophobicContact CB-CB 4.16Å; M420-E423 PolarHBondContact O-N 2.9Å
421P89.6Confident86.3Confident0 Ų062.1 Ų62.10%031%0.313CS..THydrogen-bonded Turntrans-58.5138.6172.7-23.133.7000110.4R386 W387 V409 W412 E413 K419 E423 L440R386-P421 HydrophobicContact CB-CB 4.32Å; R386-P421 WeakPolarHBondContact CD-O 3.35Å; R386-P421 PolarHBondContact NE-O 2.82Å; W387-P421 HydrophobicContact CH2-CG 4.22Å; W387-P421 HydrophobicContact CZ2-CG 3.79Å; V409-P421 HydrophobicContact CG1-CB 3.91Å; V409-P421 HydrophobicContact CG1-CG 3.54Å; W412-P421 HydrophobicContact CE3-CB 4.41Å; W412-P421 HydrophobicContact CE3-CG 4.19Å; W412-P421 HydrophobicContact CZ3-CB 4.27Å; W412-P421 HydrophobicContact CZ3-CG 4.14Å; E413-P421 HydrophobicContact CG-CG 3.89Å; K419-P421 WeakPolarHBondContact O-CD 3.35Å; P421-E423 VanDerWaalsContact C-N 3.26Å; P421-E423 PolarHBondContact O-N 3.42Å; P421-L440 HydrophobicContact CB-CD1 4.16Å; P421-L440 HydrophobicContact CB-CD2 4.1Å
422Y90.8Very high86.1Confident13 Ų1366.9 Ų66.95%0.05134%0.335CS..THydrogen-bonded Turntrans5438.9179.2-48.8-80.4000113.6R386 M420 R424 F425 T430 I434 L438 L440R386-Y422 HydrophobicContact CB-CD2 4.21Å; R386-Y422 HydrophobicContact CG-CD2 4.44Å; M420-Y422 PolarHBondContact O-N 2.9Å; Y422-R424 PolarHBondContact O-N 3.27Å; Y422-F425 PolarHBondContact O-N 2.66Å; Y422-T430 HydrophobicContact CD1-CG2 4.33Å; Y422-T430 HydrophobicContact CD2-CG2 3.58Å; Y422-T430 HydrophobicContact CE2-CG2 4.13Å; Y422-T430 HydrophobicContact CG-CG2 3.68Å; Y422-I434 HydrophobicContact CD2-CD1 4.44Å; Y422-I434 HydrophobicContact CE1-CD1 4.46Å; Y422-I434 HydrophobicContact CE1-CG1 4.16Å; Y422-I434 HydrophobicContact CE2-CD1 3.75Å; Y422-I434 HydrophobicContact CE2-CG1 4.33Å; Y422-L438 HydrophobicContact CD1-CD2 4.11Å; Y422-L438 HydrophobicContact CE1-CD2 4.25Å; Y422-L438 HydrophobicContact CE1-CG 4.41Å; Y422-L440 HydrophobicContact CD1-CD2 3.75Å; Y422-L440 HydrophobicContact CD1-CG 4.41Å; Y422-L440 HydrophobicContact CD2-CD2 3.88Å; Y422-L440 HydrophobicContact CD2-CG 4.46Å; Y422-L440 HydrophobicContact CE1-CD2 3.69Å; Y422-L440 HydrophobicContact CE1-CG 3.84Å; Y422-L440 HydrophobicContact CE2-CD1 4.13Å; Y422-L440 HydrophobicContact CE2-CD2 3.81Å; Y422-L440 HydrophobicContact CE2-CG 3.88Å; Y422-L440 HydrophobicContact CG-CD2 3.86Å
423E87.8Confident86Confident107 Ų10769.4 Ų69.450%0.535%0.347SS..THydrogen-bonded Turntrans-54-24-172.968.1-171.215400115.5M420 P421 F425M420-E423 HydrophobicContact CB-CB 4.16Å; M420-E423 PolarHBondContact O-N 2.9Å; P421-E423 VanDerWaalsContact C-N 3.26Å; P421-E423 PolarHBondContact O-N 3.42Å; E423-F425 VanDerWaalsContact C-N 3.3Å
424R90.4Very high86Confident219 Ų21967.7 Ų67.783%0.82634%0.339SS*.THydrogen-bonded Turntrans-77.3-13.4178.4-61.1-174.7-177.7-175.90.2114.1Y422Y422-R424 PolarHBondContact O-N 3.27Å
425F86.9Confident86Confident61 Ų6164.2 Ų64.227%0.26833%0.326SS..SBendtrans-119.1143-171.7-57.5-64.8000111R386 Y422 E423 E429 T430 H433 L438R386-F425 PolarHBondContact NH2-O 3.49Å; Y422-F425 PolarHBondContact O-N 2.66Å; E423-F425 VanDerWaalsContact C-N 3.3Å; F425-E429 HydrophobicContact CB-CB 4.04Å; F425-E429 HydrophobicContact CD1-CB 4.3Å; F425-T430 WeakPolarHBondContact CB-OG1 3.42Å; F425-H433 AromaticContact CD1-CD2 3.71Å; F425-H433 AromaticContact CD1-NE2 3.96Å; F425-H433 AromaticContact CE1-CD2 3.59Å; F425-H433 AromaticContact CE1-NE2 3.67Å; F425-H433 AromaticContact CZ-CD2 3.95Å; F425-L438 HydrophobicContact CD2-CD2 4.19Å; F425-L438 HydrophobicContact CE2-CD2 3.63Å; F425-L438 HydrophobicContact CZ-CD2 4.27Å
426T81.8Confident86.1Confident75 Ų7566.6 Ų66.646%0.4634%0.34SS..  trans-65.8168.3165.264.90000110.5S428 E429 T430T426-S428 VanDerWaalsContact C-N 3.3Å; T426-S428 PolarHBondContact O-N 3.26Å; T426-E429 VanDerWaalsContact CB-OE2 3.31Å; T426-E429 WeakPolarHBondContact CB-OE2 3.26Å; T426-E429 WeakPolarHBondContact CG2-OE2 3.39Å; T426-E429 PolarHBondContact N-OE2 2.91Å; T426-E429 PolarHBondContact O-N 3.34Å; T426-E429 VanDerWaalsContact OG1-CD 3.26Å; T426-E429 WeakPolarHBondContact OG1-CG 3.36Å; T426-E429 PolarHBondContact OG1-N 2.78Å; T426-E429 PolarHBondContact OG1-OE2 3.3Å; T426-T430 VanDerWaalsContact O-CB 3.3Å; T426-T430 WeakPolarHBondContact O-CB 3.38Å; T426-T430 PolarHBondContact O-N 3.07Å; T426-T430 PolarHBondContact O-OG1 2.87Å
427N76.5Confident86.3Confident68 Ų6868 Ų6836%0.36436%0.356SS..Hα-helixtrans-59.1-41.6177-82.75.3000112.1V385 R386 T430 A431V385-N427 HydrophobicContact CB-CB 4.06Å; V385-N427 HydrophobicContact CG1-CB 4.15Å; V385-N427 VanDerWaalsContact CG1-O 3.29Å; V385-N427 WeakPolarHBondContact CG1-O 3.4Å; V385-N427 HydrophobicContact CG2-CB 3.95Å; R386-N427 PolarHBondContact NH1-OD1 2.86Å; N427-T430 PolarHBondContact O-N 2.82Å; N427-A431 PolarHBondContact O-N 3.14Å
428S76.9Confident86.7Confident99 Ų9965.1 Ų65.169%0.69234%0.341SS*.Hα-helixtrans-64.8-47.7-179.6-54.20000111.8T426 T430 A431 E432T426-S428 VanDerWaalsContact C-N 3.3Å; T426-S428 PolarHBondContact O-N 3.26Å; S428-T430 VanDerWaalsContact C-N 3.33Å; S428-T430 PolarHBondContact O-N 3.35Å; S428-A431 PolarHBondContact O-N 3.34Å; S428-E432 PolarHBondContact O-N 2.87Å; S428-E432 VanDerWaalsContact O-N 3.17Å
429E85.8Confident87.4Confident83 Ų8365.8 Ų65.839%0.38834%0.336SS..Hα-helixtrans-63.9-38.9176.5-67.3161.6147.300111.7F425 T426 A431 E432 H433F425-E429 HydrophobicContact CB-CB 4.04Å; F425-E429 HydrophobicContact CD1-CB 4.3Å; T426-E429 VanDerWaalsContact CB-OE2 3.31Å; T426-E429 WeakPolarHBondContact CB-OE2 3.26Å; T426-E429 WeakPolarHBondContact CG2-OE2 3.39Å; T426-E429 PolarHBondContact N-OE2 2.91Å; T426-E429 PolarHBondContact O-N 3.34Å; T426-E429 VanDerWaalsContact OG1-CD 3.26Å; T426-E429 WeakPolarHBondContact OG1-CG 3.36Å; T426-E429 PolarHBondContact OG1-N 2.78Å; T426-E429 PolarHBondContact OG1-OE2 3.3Å; E429-A431 VanDerWaalsContact C-N 3.3Å; E429-A431 PolarHBondContact O-N 3.11Å; E429-E432 PolarHBondContact O-N 2.81Å; E429-H433 WeakPolarHBondContact O-CB 3.46Å; E429-H433 PolarHBondContact O-CD2 2.89Å; E429-H433 VanDerWaalsContact O-CD2 3.31Å; E429-H433 PolarHBondContact O-N 2.96Å
430T84.6Confident87.9Confident0 Ų062.6 Ų62.60%032%0.323CS..Hα-helixtrans-59.5-44.5176.2-58.80000110.7R386 Y422 F425 T426 N427 S428 E432 H433 I434R386-T430 HydrophobicContact CG-CG2 4.1Å; Y422-T430 HydrophobicContact CD1-CG2 4.33Å; Y422-T430 HydrophobicContact CD2-CG2 3.58Å; Y422-T430 HydrophobicContact CE2-CG2 4.13Å; Y422-T430 HydrophobicContact CG-CG2 3.68Å; F425-T430 WeakPolarHBondContact CB-OG1 3.42Å; T426-T430 VanDerWaalsContact O-CB 3.3Å; T426-T430 WeakPolarHBondContact O-CB 3.38Å; T426-T430 PolarHBondContact O-N 3.07Å; T426-T430 PolarHBondContact O-OG1 2.87Å; N427-T430 PolarHBondContact O-N 2.82Å; S428-T430 VanDerWaalsContact C-N 3.33Å; S428-T430 PolarHBondContact O-N 3.35Å; T430-E432 PolarHBondContact O-N 2.74Å; T430-H433 PolarHBondContact O-N 3.46Å; T430-I434 HydrophobicContact CG2-CD1 3.55Å; T430-I434 HydrophobicContact CG2-CG1 4.16Å; T430-I434 WeakPolarHBondContact O-CB 3.48Å; T430-I434 VanDerWaalsContact O-CG1 3.23Å; T430-I434 WeakPolarHBondContact O-CG1 3.32Å; T430-I434 PolarHBondContact O-N 3.04Å
431A82Confident88.5Confident27 Ų2763.6 Ų63.622%0.22332%0.323CS..Hα-helixtrans-63.8-42-179.600000112.1V385 L393 N427 S428 E429 A435V385-A431 HydrophobicContact CG1-CB 4.08Å; L393-A431 HydrophobicContact CD1-CB 3.94Å; L393-A431 HydrophobicContact CD2-CB 4.39Å; N427-A431 PolarHBondContact O-N 3.14Å; S428-A431 PolarHBondContact O-N 3.34Å; E429-A431 VanDerWaalsContact C-N 3.3Å; E429-A431 PolarHBondContact O-N 3.11Å; A431-A435 WeakPolarHBondContact O-CB 3.37Å; A431-A435 PolarHBondContact O-N 2.97Å
432E85.8Confident88.8Confident113 Ų11368.6 Ų68.653%0.52834%0.341SS..Hα-helixtrans-64.6-47.2176.5-176.3178178.100112.1S428 E429 T430 A435 Q436S428-E432 PolarHBondContact O-N 2.87Å; S428-E432 VanDerWaalsContact O-N 3.17Å; E429-E432 PolarHBondContact O-N 2.81Å; T430-E432 PolarHBondContact O-N 2.74Å; E432-A435 WeakPolarHBondContact O-CB 3.16Å; E432-A435 PolarHBondContact O-N 3.24Å; E432-Q436 WeakPolarHBondContact O-CG 3.26Å; E432-Q436 PolarHBondContact O-N 2.93Å; E432-Q436 VanDerWaalsContact O-N 3.11Å; E432-Q436 PolarHBondContact OE1-NE2 3.01Å
433H91.3Very high89Confident54 Ų5468.1 Ų68.125%0.2534%0.34CS..Hα-helixtrans-70.5-36.5-178.2-68.6-36.3000113.1F425 E429 T430 A435 Q436 G437 L438F425-H433 AromaticContact CD1-CD2 3.71Å; F425-H433 AromaticContact CD1-NE2 3.96Å; F425-H433 AromaticContact CE1-CD2 3.59Å; F425-H433 AromaticContact CE1-NE2 3.67Å; F425-H433 AromaticContact CZ-CD2 3.95Å; E429-H433 WeakPolarHBondContact O-CB 3.46Å; E429-H433 PolarHBondContact O-CD2 2.89Å; E429-H433 VanDerWaalsContact O-CD2 3.31Å; E429-H433 PolarHBondContact O-N 2.96Å; T430-H433 PolarHBondContact O-N 3.46Å; H433-A435 VanDerWaalsContact C-N 3.25Å; H433-A435 PolarHBondContact O-N 3.23Å; H433-Q436 PolarHBondContact ND1-OE1 2.79Å; H433-Q436 VanDerWaalsContact ND1-OE1 3.12Å; H433-Q436 CarbonylContact O-C 3.51Å; H433-Q436 PolarHBondContact O-N 3.21Å; H433-Q436 VanDerWaalsContact O-N 3.1Å; H433-G437 PolarHBondContact O-N 3.02Å; H433-L438 HydrophobicContact CB-CB 3.78Å; H433-L438 HydrophobicContact CB-CD2 3.55Å; H433-L438 HydrophobicContact CB-CG 4.29Å; H433-L438 WeakPolarHBondContact O-CB 3.47Å; H433-L438 PolarHBondContact O-N 2.79Å
434I90.4Very high89.2Confident1 Ų171.2 Ų71.21%0.00535%0.354CS..Hα-helixtrans-58.3-42.7173.8-76.6173.6000110.5P390 L393 W405 Y422 T430 Q436 G437 R439P390-I434 HydrophobicContact CG-CG2 3.81Å; L393-I434 HydrophobicContact CD1-CD1 4.5Å; L393-I434 HydrophobicContact CD1-CG2 4.25Å; W405-I434 HydrophobicContact CH2-CG2 3.84Å; W405-I434 HydrophobicContact CZ2-CG2 3.62Å; Y422-I434 HydrophobicContact CD2-CD1 4.44Å; Y422-I434 HydrophobicContact CE1-CD1 4.46Å; Y422-I434 HydrophobicContact CE1-CG1 4.16Å; Y422-I434 HydrophobicContact CE2-CD1 3.75Å; Y422-I434 HydrophobicContact CE2-CG1 4.33Å; T430-I434 HydrophobicContact CG2-CD1 3.55Å; T430-I434 HydrophobicContact CG2-CG1 4.16Å; T430-I434 WeakPolarHBondContact O-CB 3.48Å; T430-I434 VanDerWaalsContact O-CG1 3.23Å; T430-I434 WeakPolarHBondContact O-CG1 3.32Å; T430-I434 PolarHBondContact O-N 3.04Å; I434-Q436 VanDerWaalsContact C-N 3.3Å; I434-Q436 PolarHBondContact O-N 3.21Å; I434-G437 PolarHBondContact O-N 2.84Å; I434-G437 VanDerWaalsContact O-N 3.15Å; I434-R439 PolarHBondContact O-NH1 3.18Å
435A86.1Confident89.3Confident32 Ų3266.1 Ų66.126%0.26434%0.343SS..Hα-helixtrans-63.3-33175.700000113.3M394 A431 E432 H433 G437M394-A435 HydrophobicContact CE-CB 3.14Å; A431-A435 WeakPolarHBondContact O-CB 3.37Å; A431-A435 PolarHBondContact O-N 2.97Å; E432-A435 WeakPolarHBondContact O-CB 3.16Å; E432-A435 PolarHBondContact O-N 3.24Å; H433-A435 VanDerWaalsContact C-N 3.25Å; H433-A435 PolarHBondContact O-N 3.23Å; A435-G437 PolarHBondContact O-N 3.39Å
436Q92.3Very high89.6Confident128 Ų12863.3 Ų63.360%0.59833%0.33SS*.THydrogen-bonded Turntrans-80.5-1.3176.2-68.3166-5.500113.6E432 H433 I434E432-Q436 WeakPolarHBondContact O-CG 3.26Å; E432-Q436 PolarHBondContact O-N 2.93Å; E432-Q436 VanDerWaalsContact O-N 3.11Å; E432-Q436 PolarHBondContact OE1-NE2 3.01Å; H433-Q436 PolarHBondContact ND1-OE1 2.79Å; H433-Q436 VanDerWaalsContact ND1-OE1 3.12Å; H433-Q436 CarbonylContact O-C 3.51Å; H433-Q436 PolarHBondContact O-N 3.21Å; H433-Q436 VanDerWaalsContact O-N 3.1Å; I434-Q436 VanDerWaalsContact C-N 3.3Å; I434-Q436 PolarHBondContact O-N 3.21Å
437G92.6Very high90.2Very high42 Ų4261.6 Ų61.643%0.43332%0.321SS..THydrogen-bonded Turntrans102.34.1178.200000115H433 I434 A435 R439H433-G437 PolarHBondContact O-N 3.02Å; I434-G437 PolarHBondContact O-N 2.84Å; I434-G437 VanDerWaalsContact O-N 3.15Å; A435-G437 PolarHBondContact O-N 3.39Å; G437-R439 VanDerWaalsContact C-NH1 3.31Å; G437-R439 PolarHBondContact O-N 3.03Å; G437-R439 PolarHBondContact O-NH1 2.93Å
438L95.8Very high91.1Very high64 Ų6465.4 Ų65.434%0.33534%0.337SS..  trans-61.3133.2173.2-176.369.5000110.2Y422 F425 H433Y422-L438 HydrophobicContact CD1-CD2 4.11Å; Y422-L438 HydrophobicContact CE1-CD2 4.25Å; Y422-L438 HydrophobicContact CE1-CG 4.41Å; F425-L438 HydrophobicContact CD2-CD2 4.19Å; F425-L438 HydrophobicContact CE2-CD2 3.63Å; F425-L438 HydrophobicContact CZ-CD2 4.27Å; H433-L438 HydrophobicContact CB-CB 3.78Å; H433-L438 HydrophobicContact CB-CD2 3.55Å; H433-L438 HydrophobicContact CB-CG 4.29Å; H433-L438 WeakPolarHBondContact O-CB 3.47Å; H433-L438 PolarHBondContact O-N 2.79Å
439R97.2Very high91.9Very high36 Ų3665.8 Ų65.814%0.13633%0.326CS..  trans-125.8157.7174.2-60.8-59.3179-95.30.1110.3I434 G437 Y455 W458I434-R439 PolarHBondContact O-NH1 3.18Å; G437-R439 VanDerWaalsContact C-NH1 3.31Å; G437-R439 PolarHBondContact O-N 3.03Å; G437-R439 PolarHBondContact O-NH1 2.93Å; R439-Y455 HydrophobicContact CB-CD2 4.46Å; R439-Y455 HydrophobicContact CB-CE2 3.73Å; R439-Y455 HydrophobicContact CG-CE2 3.95Å; R439-W458 HydrophobicContact CB-CE3 4.31Å; R439-W458 PolarHBondContact NE-O 3.2Å; R439-W458 PolarHBondContact NH2-O 2.82Å; R439-W458 VanDerWaalsContact NH2-O 3.15Å
440L96.3Very high92.3Very high5 Ų562.1 Ų62.13%0.02631%0.31CS..PPolyproline II helixtrans-65.3141.4175.8-69.1165.2000109.5V409 W412 P421 Y422 Y451 W458V409-L440 HydrophobicContact CG1-CD1 4.17Å; V409-L440 HydrophobicContact CG2-CD1 4.24Å; W412-L440 HydrophobicContact CB-CD1 4.01Å; W412-L440 HydrophobicContact CD2-CB 4.36Å; W412-L440 HydrophobicContact CD2-CD1 3.83Å; W412-L440 HydrophobicContact CD2-CD2 4.31Å; W412-L440 HydrophobicContact CD2-CG 4.39Å; W412-L440 HydrophobicContact CE3-CD1 4.21Å; W412-L440 HydrophobicContact CG-CB 4.07Å; W412-L440 HydrophobicContact CG-CD1 3.71Å; W412-L440 HydrophobicContact CG-CG 4.39Å; W412-L440 HydrophobicContact CZ2-CD2 4.26Å; P421-L440 HydrophobicContact CB-CD1 4.16Å; P421-L440 HydrophobicContact CB-CD2 4.1Å; Y422-L440 HydrophobicContact CD1-CD2 3.75Å; Y422-L440 HydrophobicContact CD1-CG 4.41Å; Y422-L440 HydrophobicContact CD2-CD2 3.88Å; Y422-L440 HydrophobicContact CD2-CG 4.46Å; Y422-L440 HydrophobicContact CE1-CD2 3.69Å; Y422-L440 HydrophobicContact CE1-CG 3.84Å; Y422-L440 HydrophobicContact CE2-CD1 4.13Å; Y422-L440 HydrophobicContact CE2-CD2 3.81Å; Y422-L440 HydrophobicContact CE2-CG 3.88Å; Y422-L440 HydrophobicContact CG-CD2 3.86Å; L440-Y451 PolarHBondContact O-OH 2.87Å; L440-W458 HydrophobicContact CB-CH2 3.68Å; L440-W458 HydrophobicContact CB-CZ2 4.37Å; L440-W458 HydrophobicContact CB-CZ3 3.9Å; L440-W458 HydrophobicContact CD1-CH2 3.88Å; L440-W458 HydrophobicContact CD1-CZ2 3.75Å; L440-W458 HydrophobicContact CG-CH2 4.29Å
441Y96.8Very high92.9Very high109 Ų10964.3 Ų64.343%0.42732%0.318SS..PPolyproline II helixtrans-71.9161.2177.764.7-91.1000111.6W412 P443W412-Y441 VanDerWaalsContact CD1-O 3.28Å; W412-Y441 HydrophobicContact CZ2-CD1 4.45Å; W412-Y441 AromaticContact CZ2-CE1 3.75Å; W412-Y441 HydrophobicContact CZ2-CE1 3.75Å; W412-Y441 HydrophobicContact CZ2-CE2 4.38Å; W412-Y441 AromaticContact CZ2-CZ 3.7Å; W412-Y441 PolarHBondContact NE1-O 3.28Å; Y441-P443 VanDerWaalsContact O-CD 3.27Å; Y441-P443 WeakPolarHBondContact O-CD 3.37Å
442R97.4Very high93.6Very high104 Ų10467.4 Ų67.439%0.39234%0.335SS..PPolyproline II helixtrans-65.9118.1175-176.4172.97479-2.4111.9A446 Y451R442-A446 HydrophobicContact CG-CB 4.39Å; R442-A446 PolarHBondContact NH1-O 3.1Å; R442-Y451 VanDerWaalsContact CA-CD2 3.48Å; R442-Y451 HydrophobicContact CB-CD1 3.97Å; R442-Y451 HydrophobicContact CB-CD2 3.6Å; R442-Y451 HydrophobicContact CB-CE1 4.1Å; R442-Y451 HydrophobicContact CB-CE2 3.75Å; R442-Y451 HydrophobicContact CB-CG 3.71Å; R442-Y451 HydrophobicContact CG-CD1 4.19Å; R442-Y451 HydrophobicContact CG-CD2 3.74Å; R442-Y451 HydrophobicContact CG-CE2 4.4Å; R442-Y451 HydrophobicContact CG-CG 3.6Å
443P93.9Very high94.1Very high3 Ų362.6 Ų62.62%0.01931%0.312CS..PPolyproline II helixtrans-60.8147.8172.3-21.233.3000111.6W412 Y415 S416 Y441 L445 A446W412-P443 VanDerWaalsContact CD1-CG 3.48Å; W412-P443 HydrophobicContact CG-CG 4.1Å; Y415-P443 WeakPolarHBondContact O-CB 3.26Å; S416-P443 WeakPolarHBondContact OG-CB 3.27Å; S416-P443 VanDerWaalsContact OG-CG 3.3Å; S416-P443 WeakPolarHBondContact OG-CG 3.35Å; Y441-P443 VanDerWaalsContact O-CD 3.27Å; Y441-P443 WeakPolarHBondContact O-CD 3.37Å; P443-L445 PolarHBondContact O-N 2.95Å; P443-A446 HydrophobicContact CB-CB 4.23Å; P443-A446 HydrophobicContact CG-CB 4.33Å; P443-A446 PolarHBondContact O-N 2.89Å
444H92.6Very high94.3Very high173 Ų17360 Ų6080%0.80130%0.3SS*.THydrogen-bonded Turntrans-59.9-32.8-179.1-67.5-61000113.6A446H444-A446 VanDerWaalsContact C-N 3.34Å
445L92.1Very high94.6Very high112 Ų11265.3 Ų65.359%0.58632%0.321SS*.THydrogen-bonded Turntrans-81.2-11.4179.2-61.2176.9000113.6Y415 L417 P443Y415-L445 HydrophobicContact CD1-CB 4.26Å; Y415-L445 WeakPolarHBondContact CD1-O 3.33Å; L417-L445 HydrophobicContact CD1-CD1 4.07Å; L417-L445 HydrophobicContact CD2-CD1 3.87Å; L417-L445 HydrophobicContact CG-CD1 3.9Å; P443-L445 PolarHBondContact O-N 2.95Å
446A93.3Very high95.1Very high1 Ų165.7 Ų65.71%0.00832%0.322CS..SBendtrans-89.7122.8-179.800000110.2Y415 R442 P443 H444 V450 M454Y415-A446 HydrophobicContact CD1-CB 3.81Å; Y415-A446 HydrophobicContact CE1-CB 4.48Å; Y415-A446 HydrophobicContact CG-CB 3.93Å; R442-A446 HydrophobicContact CG-CB 4.39Å; R442-A446 PolarHBondContact NH1-O 3.1Å; P443-A446 HydrophobicContact CB-CB 4.23Å; P443-A446 HydrophobicContact CG-CB 4.33Å; P443-A446 PolarHBondContact O-N 2.89Å; H444-A446 VanDerWaalsContact C-N 3.34Å; A446-V450 HydrophobicContact CB-CB 4.44Å; A446-V450 HydrophobicContact CB-CG1 4Å; A446-M454 HydrophobicContact CB-CE 3.88Å
447S94.5Very high95.4Very high39 Ų3959.6 Ų59.627%0.27329%0.293SS..  trans-62.8165.4169.472.50000111.3K449 V450 Y451S447-K449 VanDerWaalsContact C-N 3.25Å; S447-K449 PolarHBondContact O-N 2.83Å; S447-V450 PolarHBondContact O-N 2.86Å; S447-V450 WeakPolarHBondContact OG-CG2 3.34Å; S447-V450 PolarHBondContact OG-N 3.08Å; S447-Y451 WeakPolarHBondContact O-CB 3.45Å; S447-Y451 PolarHBondContact O-N 2.79Å
448E94.6Very high95.6Very high149 Ų14957.7 Ų57.770%0.69627%0.273SS*.Hα-helixtrans-61.7-34.7177.1-70.5-165.5162.600112.7Y451 T452E448-Y451 PolarHBondContact O-N 2.82Å; E448-T452 WeakPolarHBondContact O-CB 3.41Å; E448-T452 PolarHBondContact O-N 2.9Å; E448-T452 PolarHBondContact O-OG1 3.17Å
449K94.2Very high95.7Very high106 Ų10658.6 Ų58.646%0.46128%0.275SS..Hα-helixtrans-66.1-49.1175.9-65.8-170.9-179.5-177.10111.2S447 Y451 T452 I453 V478 E481S447-K449 VanDerWaalsContact C-N 3.25Å; S447-K449 PolarHBondContact O-N 2.83Å; K449-Y451 VanDerWaalsContact C-N 3.28Å; K449-Y451 PolarHBondContact O-N 3.28Å; K449-T452 WeakPolarHBondContact O-CB 3.46Å; K449-T452 PolarHBondContact O-N 3.05Å; K449-I453 WeakPolarHBondContact O-CG1 3.17Å; K449-I453 PolarHBondContact O-N 2.81Å; K449-I453 VanDerWaalsContact O-N 3.14Å; K449-V478 HydrophobicContact CB-CG2 3.91Å; K449-V478 HydrophobicContact CD-CG2 4.47Å; K449-E481 VanDerWaalsContact CD-OE2 3.27Å; K449-E481 WeakPolarHBondContact CD-OE2 3.36Å; K449-E481 WeakPolarHBondContact CE-OE2 3.47Å; K449-E481 IonicContact NZ-OE1 2.97Å; K449-E481 PolarHBondContact NZ-OE1 3.09Å; K449-E481 IonicContact NZ-OE2 3.38Å; K449-E481 PolarHBondContact NZ-OE2 2.92Å
450V94.1Very high95.5Very high6 Ų663.3 Ų63.34%0.03630%0.299CS..Hα-helixtrans-58.6-42.4174.8171.20000111.2Y415 A446 S447 I453 M454 V478Y415-V450 HydrophobicContact CD1-CG1 4.29Å; Y415-V450 HydrophobicContact CD2-CG1 3.84Å; Y415-V450 HydrophobicContact CE1-CG1 3.83Å; Y415-V450 HydrophobicContact CE2-CG1 3.35Å; Y415-V450 HydrophobicContact CG-CG1 4.29Å; A446-V450 HydrophobicContact CB-CB 4.44Å; A446-V450 HydrophobicContact CB-CG1 4Å; S447-V450 PolarHBondContact O-N 2.86Å; S447-V450 WeakPolarHBondContact OG-CG2 3.34Å; S447-V450 PolarHBondContact OG-N 3.08Å; V450-I453 WeakPolarHBondContact O-CB 3.4Å; V450-I453 PolarHBondContact O-N 2.91Å; V450-M454 HydrophobicContact CG1-CE 3.75Å; V450-M454 PolarHBondContact O-N 2.92Å; V450-M454 VanDerWaalsContact O-N 3.16Å; V450-V478 HydrophobicContact CG2-CG1 3.92Å
451Y97.3Very high95.3Very high46 Ų4669 Ų6918%0.1832%0.323CS..Hα-helixtrans-65-40.1178.2-175.1-112.7000112.2L440 R442 S447 E448 K449 I453 M454 Y455 W458L440-Y451 PolarHBondContact O-OH 2.87Å; R442-Y451 VanDerWaalsContact CA-CD2 3.48Å; R442-Y451 HydrophobicContact CB-CD1 3.97Å; R442-Y451 HydrophobicContact CB-CD2 3.6Å; R442-Y451 HydrophobicContact CB-CE1 4.1Å; R442-Y451 HydrophobicContact CB-CE2 3.75Å; R442-Y451 HydrophobicContact CB-CG 3.71Å; R442-Y451 HydrophobicContact CG-CD1 4.19Å; R442-Y451 HydrophobicContact CG-CD2 3.74Å; R442-Y451 HydrophobicContact CG-CE2 4.4Å; R442-Y451 HydrophobicContact CG-CG 3.6Å; S447-Y451 WeakPolarHBondContact O-CB 3.45Å; S447-Y451 PolarHBondContact O-N 2.79Å; E448-Y451 PolarHBondContact O-N 2.82Å; K449-Y451 VanDerWaalsContact C-N 3.28Å; K449-Y451 PolarHBondContact O-N 3.28Å; Y451-I453 VanDerWaalsContact C-N 3.26Å; Y451-I453 PolarHBondContact O-N 2.85Å; Y451-M454 HydrophobicContact CD2-CG 3.87Å; Y451-M454 HydrophobicContact CD2-SD 3.72Å; Y451-M454 HydrophobicContact CE2-CG 4.41Å; Y451-M454 HydrophobicContact CE2-SD 4.27Å; Y451-M454 VanDerWaalsContact O-CG 3.25Å; Y451-M454 WeakPolarHBondContact O-CG 2.9Å; Y451-M454 PolarHBondContact O-N 2.64Å; Y451-Y455 AromaticContact CE1-CD2 3.91Å; Y451-Y455 HydrophobicContact CE1-CD2 3.91Å; Y451-Y455 HydrophobicContact CE1-CG 4.39Å; Y451-Y455 HydrophobicContact CE2-CD2 4.4Å; Y451-Y455 AromaticContact CZ-CD2 3.65Å; Y451-Y455 WeakPolarHBondContact O-CB 3.4Å; Y451-Y455 PolarHBondContact O-N 3.3Å; Y451-Y455 WeakPolarHBondContact OH-CD2 3.18Å; Y451-W458 HydrophobicContact CE2-CZ3 4.45Å
452T97.3Very high95Very high93 Ų9365 Ų6557%0.57131%0.313SS*.Hα-helixtrans-57.4-40.7174.2-59.80000111.5E448 K449 Y455 S456E448-T452 WeakPolarHBondContact O-CB 3.41Å; E448-T452 PolarHBondContact O-N 2.9Å; E448-T452 PolarHBondContact O-OG1 3.17Å; K449-T452 WeakPolarHBondContact O-CB 3.46Å; K449-T452 PolarHBondContact O-N 3.05Å; T452-Y455 PolarHBondContact O-N 3.23Å; T452-S456 WeakPolarHBondContact O-CB 3.37Å; T452-S456 PolarHBondContact O-N 3.14Å
453I95.6Very high94.8Very high11 Ų1165.5 Ų65.56%0.05632%0.324CS..Hα-helixtrans-62.5-54.6176.6-61.9169.7000110.8M411 K449 V450 Y451 Y455 S456 C457 L471 N474 I475 V478M411-I453 HydrophobicContact CE-CB 4.28Å; M411-I453 HydrophobicContact CE-CG2 3.86Å; M411-I453 HydrophobicContact SD-CG2 4Å; K449-I453 WeakPolarHBondContact O-CG1 3.17Å; K449-I453 PolarHBondContact O-N 2.81Å; K449-I453 VanDerWaalsContact O-N 3.14Å; V450-I453 WeakPolarHBondContact O-CB 3.4Å; V450-I453 PolarHBondContact O-N 2.91Å; Y451-I453 VanDerWaalsContact C-N 3.26Å; Y451-I453 PolarHBondContact O-N 2.85Å; I453-Y455 VanDerWaalsContact C-N 3.29Å; I453-Y455 PolarHBondContact O-N 3.11Å; I453-S456 PolarHBondContact O-N 3.01Å; I453-S456 PolarHBondContact O-OG 3.03Å; I453-C457 PolarHBondContact O-SG 2.96Å; I453-L471 HydrophobicContact CG2-CD2 3.74Å; I453-N474 HydrophobicContact CD1-CB 3.88Å; I453-N474 WeakPolarHBondContact CD1-O 3.22Å; I453-N474 HydrophobicContact CG1-CB 3.96Å; I453-I475 HydrophobicContact CD1-CG1 4.33Å; I453-I475 HydrophobicContact CG2-CG1 4.29Å; I453-V478 HydrophobicContact CD1-CG2 3.82Å
454M95.8Very high94.9Very high0 Ų071 Ų710%035%0.349CS..Hα-helixtrans-64.7-34.8-179.970.3-178.976.300112.1M411 W412 Y415 A446 V450 Y451 C457 W458M411-M454 HydrophobicContact CB-CB 3.88Å; M411-M454 HydrophobicContact CB-CE 4.44Å; M411-M454 HydrophobicContact CE-CB 4.46Å; M411-M454 HydrophobicContact SD-CB 4.02Å; W412-M454 HydrophobicContact CB-SD 4.05Å; Y415-M454 HydrophobicContact CD2-CE 4.04Å; Y415-M454 HydrophobicContact CG-CE 4.37Å; A446-M454 HydrophobicContact CB-CE 3.88Å; V450-M454 HydrophobicContact CG1-CE 3.75Å; V450-M454 PolarHBondContact O-N 2.92Å; V450-M454 VanDerWaalsContact O-N 3.16Å; Y451-M454 HydrophobicContact CD2-CG 3.87Å; Y451-M454 HydrophobicContact CD2-SD 3.72Å; Y451-M454 HydrophobicContact CE2-CG 4.41Å; Y451-M454 HydrophobicContact CE2-SD 4.27Å; Y451-M454 VanDerWaalsContact O-CG 3.25Å; Y451-M454 WeakPolarHBondContact O-CG 2.9Å; Y451-M454 PolarHBondContact O-N 2.64Å; M454-C457 VanDerWaalsContact O-CB 3.23Å; M454-C457 WeakPolarHBondContact O-CB 3.38Å; M454-C457 PolarHBondContact O-N 3.44Å; M454-W458 HydrophobicContact CB-CH2 4.43Å; M454-W458 HydrophobicContact CG-CH2 4.09Å; M454-W458 HydrophobicContact CG-CZ3 4.38Å; M454-W458 HydrophobicContact SD-CH2 4.18Å
455Y97.6Very high95.1Very high112 Ų11262.9 Ų62.944%0.43931%0.311SS..Hα-helixtrans-69.1-36.5-180-165.6-89.9000112.3R439 Y451 T452 I453 C457 W458R439-Y455 HydrophobicContact CB-CD2 4.46Å; R439-Y455 HydrophobicContact CB-CE2 3.73Å; R439-Y455 HydrophobicContact CG-CE2 3.95Å; Y451-Y455 AromaticContact CE1-CD2 3.91Å; Y451-Y455 HydrophobicContact CE1-CD2 3.91Å; Y451-Y455 HydrophobicContact CE1-CG 4.39Å; Y451-Y455 HydrophobicContact CE2-CD2 4.4Å; Y451-Y455 AromaticContact CZ-CD2 3.65Å; Y451-Y455 WeakPolarHBondContact O-CB 3.4Å; Y451-Y455 PolarHBondContact O-N 3.3Å; Y451-Y455 WeakPolarHBondContact OH-CD2 3.18Å; T452-Y455 PolarHBondContact O-N 3.23Å; I453-Y455 VanDerWaalsContact C-N 3.29Å; I453-Y455 PolarHBondContact O-N 3.11Å; Y455-C457 PolarHBondContact O-N 3Å; Y455-C457 VanDerWaalsContact O-N 3.14Å; Y455-W458 HydrophobicContact CD2-CE3 4.05Å; Y455-W458 HydrophobicContact CD2-CZ3 4.27Å; Y455-W458 PolarHBondContact O-N 3.34Å
456S97Very high95.1Very high40 Ų4058.3 Ų58.328%0.2829%0.288SS..Hα-helixtrans-58.7-25.6174.974.40000113T452 I453 W458 P466T452-S456 WeakPolarHBondContact O-CB 3.37Å; T452-S456 PolarHBondContact O-N 3.14Å; I453-S456 PolarHBondContact O-N 3.01Å; I453-S456 PolarHBondContact O-OG 3.03Å; S456-W458 PolarHBondContact O-N 3.09Å; S456-P466 VanDerWaalsContact O-CD 3.27Å; S456-P466 WeakPolarHBondContact O-CD 3.42Å
457C96.8Very high94.7Very high0 Ų061.3 Ų61.30%031%0.307CS..THydrogen-bonded Turntrans-69.9-19.5175.7-590000113.3I404 I453 M454 Y455 R465I404-C457 HydrophobicContact CG2-CB 3.89Å; I404-C457 WeakPolarHBondContact O-CB 3.44Å; I453-C457 PolarHBondContact O-SG 2.96Å; M454-C457 VanDerWaalsContact O-CB 3.23Å; M454-C457 WeakPolarHBondContact O-CB 3.38Å; M454-C457 PolarHBondContact O-N 3.44Å; Y455-C457 PolarHBondContact O-N 3Å; Y455-C457 VanDerWaalsContact O-N 3.14Å; C457-R465 VanDerWaalsContact O-CD 3.31Å; C457-R465 WeakPolarHBondContact O-CD 3.43Å
458W97.6Very high94.3Very high3 Ų364.1 Ų64.11%0.01131%0.314CS..THydrogen-bonded Turntrans-106.624.9-174.8-50.8-42000113.9W405 G408 V409 W412 R439 L440 Y451 M454 Y455 S456 E460W405-W458 HydrophobicContact CD2-CB 4.4Å; W405-W458 AromaticContact CD2-CD1 3.57Å; W405-W458 HydrophobicContact CD2-CG 4.33Å; W405-W458 AromaticContact CE2-CD1 3.7Å; W405-W458 HydrophobicContact CE3-CB 4.01Å; W405-W458 AromaticContact CE3-CD1 3.99Å; W405-W458 HydrophobicContact CE3-CG 4.41Å; W405-W458 AromaticContact CG-CD1 3.82Å; W405-W458 HydrophobicContact CH2-CB 3.99Å; W405-W458 HydrophobicContact CZ2-CB 4.38Å; W405-W458 HydrophobicContact CZ2-CG 4.45Å; W405-W458 HydrophobicContact CZ3-CB 3.8Å; W405-W458 WeakPolarHBondContact CZ3-O 3.49Å; W405-W458 AromaticContact NE1-CD1 4Å; W405-W458 PolarHBondContact O-NE1 2.83Å; G408-W458 VanDerWaalsContact O-CZ2 3.25Å; G408-W458 WeakPolarHBondContact O-CZ2 3.17Å; V409-W458 HydrophobicContact CG2-CZ2 4.21Å; W412-W458 HydrophobicContact CB-CH2 4Å; W412-W458 HydrophobicContact CB-CZ2 4.13Å; W412-W458 HydrophobicContact CG-CH2 4.35Å; R439-W458 HydrophobicContact CB-CE3 4.31Å; R439-W458 PolarHBondContact NE-O 3.2Å; R439-W458 PolarHBondContact NH2-O 2.82Å; R439-W458 VanDerWaalsContact NH2-O 3.15Å; L440-W458 HydrophobicContact CB-CH2 3.68Å; L440-W458 HydrophobicContact CB-CZ2 4.37Å; L440-W458 HydrophobicContact CB-CZ3 3.9Å; L440-W458 HydrophobicContact CD1-CH2 3.88Å; L440-W458 HydrophobicContact CD1-CZ2 3.75Å; L440-W458 HydrophobicContact CG-CH2 4.29Å; Y451-W458 HydrophobicContact CE2-CZ3 4.45Å; M454-W458 HydrophobicContact CB-CH2 4.43Å; M454-W458 HydrophobicContact CG-CH2 4.09Å; M454-W458 HydrophobicContact CG-CZ3 4.38Å; M454-W458 HydrophobicContact SD-CH2 4.18Å; Y455-W458 HydrophobicContact CD2-CE3 4.05Å; Y455-W458 HydrophobicContact CD2-CZ3 4.27Å; Y455-W458 PolarHBondContact O-N 3.34Å; S456-W458 PolarHBondContact O-N 3.09Å; W458-E460 PolarHBondContact O-N 2.8Å
459H97.3Very high93.5Very high82 Ų8265.6 Ų65.638%0.3832%0.318SS..  trans-58.1138.8169.8-165.6-83.2000110.3K461 E464 R465H459-K461 PolarHBondContact ND1-N 3.28Å; H459-K461 VanDerWaalsContact ND1-N 3.11Å; H459-K461 PolarHBondContact ND1-O 3.11Å; H459-K461 VanDerWaalsContact ND1-O 3.14Å; H459-E464 HydrophobicContact CB-CB 4.38Å; H459-E464 VanDerWaalsContact ND1-CB 3.34Å; H459-E464 WeakPolarHBondContact ND1-CB 3.45Å; H459-R465 HydrophobicContact CB-CG 3.95Å; H459-R465 PolarHBondContact O-NE 3.44Å; H459-R465 PolarHBondContact O-NH2 3.32Å
460E93.2Very high93.2Very high136 Ų13664.5 Ų64.564%0.63632%0.316SS*.SBendtrans-59.4-52.1-177.6-176.8-177.7-174.900110.9W458 R465W458-E460 PolarHBondContact O-N 2.8Å; E460-R465 PolarHBondContact O-NH2 3.46Å
461K92.8Very high92.9Very high123 Ų12364.2 Ų64.254%0.53532%0.315SS..SBendtrans-72.5129.8172.6-50.3-176.4179.9175.10110.7H459 D463 E464H459-K461 PolarHBondContact ND1-N 3.28Å; H459-K461 VanDerWaalsContact ND1-N 3.11Å; H459-K461 PolarHBondContact ND1-O 3.11Å; H459-K461 VanDerWaalsContact ND1-O 3.14Å; K461-D463 WeakPolarHBondContact CB-OD1 3.47Å; K461-E464 HydrophobicContact CB-CB 4.38Å; K461-E464 HydrophobicContact CB-CG 3.94Å; K461-E464 HydrophobicContact CD-CG 4.16Å
462A90.7Very high92.3Very high26 Ų2667 Ų6722%0.21533%0.332CS..SBendtrans-71.4-36-173.400000113.6K401 E464 R465K401-A462 HydrophobicContact CB-CB 3.89Å; K401-A462 WeakPolarHBondContact CB-O 3.45Å; K401-A462 WeakPolarHBondContact CD-O 3.34Å; K401-A462 HydrophobicContact CG-CB 4.32Å; K401-A462 WeakPolarHBondContact CG-O 3.5Å; A462-E464 VanDerWaalsContact C-N 3.35Å; A462-R465 WeakPolarHBondContact O-CB 3.35Å; A462-R465 PolarHBondContact O-N 3.39Å
463D91.9Very high91.8Very high115 Ų11565.4 Ų65.462%0.61533%0.325SS*.THydrogen-bonded Turntrans-61.6-38.817752.2-20.9000112.9K401 K461 R465K401-D463 PolarHBondContact NZ-O 2.74Å; K461-D463 WeakPolarHBondContact CB-OD1 3.47Å; D463-R465 PolarHBondContact O-N 2.75Å
464E96.3Very high91.4Very high117 Ų11767.4 Ų67.455%0.54734%0.336SS..THydrogen-bonded Turntrans-71.3-11.7177.3-61.4-67.1173.500114.1H459 K461 A462H459-E464 HydrophobicContact CB-CB 4.38Å; H459-E464 VanDerWaalsContact ND1-CB 3.34Å; H459-E464 WeakPolarHBondContact ND1-CB 3.45Å; K461-E464 HydrophobicContact CB-CB 4.38Å; K461-E464 HydrophobicContact CB-CG 3.94Å; K461-E464 HydrophobicContact CD-CG 4.16Å; A462-E464 VanDerWaalsContact C-N 3.35Å
465R96.6Very high91Very high3 Ų369.7 Ų69.71%0.01135%0.347CS..SBendtrans-71.4145.2174.9-58.9173.3-164.6152.711.6109.5E391 K401 I404 C457 H459 E460 A462 D463E391-R465 IonicContact OE1-CZ 2.72Å; E391-R465 IonicContact OE1-NH1 3.92Å; E391-R465 PolarHBondContact OE1-NH1 3.31Å; E391-R465 IonicContact OE1-NH2 3.47Å; E391-R465 PolarHBondContact OE1-NH2 3.24Å; E391-R465 IonicContact OE2-CZ 3.5Å; E391-R465 IonicContact OE2-NH1 2.99Å; E391-R465 IonicContact OE2-NH2 3.2Å; E391-R465 PolarHBondContact OE2-NH2 2.93Å; K401-R465 HydrophobicContact CD-CB 4.37Å; K401-R465 PolarHBondContact NZ-O 3.49Å; K401-R465 PolarHBondContact O-NH1 2.86Å; I404-R465 HydrophobicContact CG2-CB 4Å; C457-R465 VanDerWaalsContact O-CD 3.31Å; C457-R465 WeakPolarHBondContact O-CD 3.43Å; H459-R465 HydrophobicContact CB-CG 3.95Å; H459-R465 PolarHBondContact O-NE 3.44Å; H459-R465 PolarHBondContact O-NH2 3.32Å; E460-R465 PolarHBondContact O-NH2 3.46Å; A462-R465 WeakPolarHBondContact O-CB 3.35Å; A462-R465 PolarHBondContact O-N 3.39Å; D463-R465 PolarHBondContact O-N 2.75Å
466P92.5Very high90.5Very high16 Ų1668.2 Ų68.210%0.10435%0.347CS..PPolyproline II helixtrans-65.2168.2179.229-36.6000112.1I404 S456 I470 L471I404-P466 WeakPolarHBondContact CD1-O 3.35Å; I404-P466 WeakPolarHBondContact CG1-O 3.23Å; I404-P466 HydrophobicContact CG2-CG 4.33Å; S456-P466 VanDerWaalsContact O-CD 3.27Å; S456-P466 WeakPolarHBondContact O-CD 3.42Å; P466-I470 HydrophobicContact CB-CB 4.09Å; P466-I470 HydrophobicContact CB-CG2 3.92Å; P466-L471 HydrophobicContact CB-CD2 4.2Å; P466-L471 HydrophobicContact CB-CG 4.13Å; P466-L471 HydrophobicContact CG-CD1 4.27Å; P466-L471 HydrophobicContact CG-CD2 3.54Å; P466-L471 HydrophobicContact CG-CG 3.79Å
467T86.1Confident90.2Very high64 Ų6470.4 Ų70.439%0.39336%0.355SS..PPolyproline II helixtrans-89.9161167.1650000110K469 I470 L471T467-K469 PolarHBondContact O-N 3.24Å; T467-I470 PolarHBondContact O-N 3.36Å; T467-I470 WeakPolarHBondContact OG1-CG1 3.44Å; T467-I470 PolarHBondContact OG1-N 3.37Å; T467-L471 PolarHBondContact O-N 2.78Å
468F84.4Confident89.9Confident98 Ų9871.2 Ų71.243%0.4336%0.36SS..Hα-helixtrans-57.7-30.3173.3-79.6-67.3000112.8D403 I404 F407 L471 L472D403-F468 HydrophobicContact CB-CE2 4.15Å; D403-F468 HydrophobicContact CB-CZ 4.29Å; I404-F468 HydrophobicContact CD1-CB 4.44Å; I404-F468 HydrophobicContact CD1-CD1 3.88Å; I404-F468 HydrophobicContact CD1-CD2 3.64Å; I404-F468 HydrophobicContact CD1-CE1 3.96Å; I404-F468 HydrophobicContact CD1-CE2 3.71Å; I404-F468 HydrophobicContact CD1-CG 3.71Å; I404-F468 HydrophobicContact CD1-CZ 3.87Å; I404-F468 HydrophobicContact CG1-CE2 4.28Å; F407-F468 HydrophobicContact CB-CE1 3.77Å; F407-F468 HydrophobicContact CB-CZ 4.1Å; F407-F468 HydrophobicContact CD1-CE1 4.21Å; F407-F468 AromaticContact CD2-CE1 3.92Å; F407-F468 HydrophobicContact CD2-CE1 3.92Å; F407-F468 AromaticContact CG-CE1 3.7Å; F407-F468 HydrophobicContact CG-CE1 3.7Å; F407-F468 HydrophobicContact CG-CZ 4.49Å; F468-L471 HydrophobicContact CD1-CD1 4.26Å; F468-L471 PolarHBondContact O-N 2.87Å; F468-L472 VanDerWaalsContact O-CB 3.32Å; F468-L472 WeakPolarHBondContact O-CB 3.44Å; F468-L472 PolarHBondContact O-N 2.99Å
469K79.1Confident89.2Confident180 Ų18076.2 Ų76.278%0.78339%0.385SS*.Hα-helixtrans-63.6-44.2174.3-175.2178.4179.6-179.30111.6T467 S473T467-K469 PolarHBondContact O-N 3.24Å; K469-S473 PolarHBondContact O-N 2.79Å; K469-S473 VanDerWaalsContact O-N 3.14Å
470I87.4Confident88.6Confident83 Ų8377.8 Ų77.843%0.42640%0.396SS..Hα-helixtrans-66.8-45.6176.5-65.8167.6000110P466 T467 L472 S473 N474P466-I470 HydrophobicContact CB-CB 4.09Å; P466-I470 HydrophobicContact CB-CG2 3.92Å; T467-I470 PolarHBondContact O-N 3.36Å; T467-I470 WeakPolarHBondContact OG1-CG1 3.44Å; T467-I470 PolarHBondContact OG1-N 3.37Å; I470-L472 VanDerWaalsContact C-N 3.32Å; I470-L472 PolarHBondContact O-N 3.18Å; I470-S473 WeakPolarHBondContact O-CB 3.48Å; I470-S473 PolarHBondContact O-N 2.98Å; I470-N474 VanDerWaalsContact O-CG 3.26Å; I470-N474 PolarHBondContact O-N 3.49Å; I470-N474 PolarHBondContact O-OD1 3.29Å
471L87.1Confident87.8Confident1 Ų176.8 Ų76.81%0.00539%0.392CS..Hα-helixtrans-59.4-43177.7-70.4174.6000112.3I404 F407 I453 P466 T467 F468 N474 I475I404-L471 HydrophobicContact CD1-CD1 3.64Å; I404-L471 HydrophobicContact CG2-CD1 4.24Å; F407-L471 HydrophobicContact CD1-CD1 3.67Å; F407-L471 HydrophobicContact CE1-CB 4.49Å; F407-L471 HydrophobicContact CE1-CD1 3.89Å; I453-L471 HydrophobicContact CG2-CD2 3.74Å; P466-L471 HydrophobicContact CB-CD2 4.2Å; P466-L471 HydrophobicContact CB-CG 4.13Å; P466-L471 HydrophobicContact CG-CD1 4.27Å; P466-L471 HydrophobicContact CG-CD2 3.54Å; P466-L471 HydrophobicContact CG-CG 3.79Å; T467-L471 PolarHBondContact O-N 2.78Å; F468-L471 HydrophobicContact CD1-CD1 4.26Å; F468-L471 PolarHBondContact O-N 2.87Å; L471-N474 PolarHBondContact O-N 2.95Å; L471-I475 WeakPolarHBondContact O-CB 3.29Å; L471-I475 WeakPolarHBondContact O-CD1 3.36Å; L471-I475 WeakPolarHBondContact O-CG1 3.21Å; L471-I475 PolarHBondContact O-N 3.08Å
472L84.4Confident86.2Confident104 Ų10477.7 Ų77.755%0.54540%0.398SS..Hα-helixtrans-61.4-45.2176.618062000111.4F468 I470 N474 I475 L476F468-L472 VanDerWaalsContact O-CB 3.32Å; F468-L472 WeakPolarHBondContact O-CB 3.44Å; F468-L472 PolarHBondContact O-N 2.99Å; I470-L472 VanDerWaalsContact C-N 3.32Å; I470-L472 PolarHBondContact O-N 3.18Å; L472-N474 PolarHBondContact O-N 3.19Å; L472-I475 PolarHBondContact O-N 2.99Å; L472-L476 HydrophobicContact CD1-CD1 4.33Å; L472-L476 HydrophobicContact CD1-CG 4.32Å; L472-L476 HydrophobicContact CG-CD1 4.18Å; L472-L476 VanDerWaalsContact O-CG 3.31Å; L472-L476 WeakPolarHBondContact O-CG 3.34Å; L472-L476 PolarHBondContact O-N 3.48Å
473S87.3Confident84.2Confident59 Ų5983.6 Ų83.641%0.41344%0.438SS..Hα-helixtrans-55.8-51.6174.8-163.60000111K469 I470 I475 L476 D477K469-S473 PolarHBondContact O-N 2.79Å; K469-S473 VanDerWaalsContact O-N 3.14Å; I470-S473 WeakPolarHBondContact O-CB 3.48Å; I470-S473 PolarHBondContact O-N 2.98Å; S473-I475 VanDerWaalsContact C-N 3.29Å; S473-I475 PolarHBondContact O-N 3.1Å; S473-L476 PolarHBondContact O-N 3.33Å; S473-L476 VanDerWaalsContact O-N 3.16Å; S473-D477 VanDerWaalsContact O-CG 3.26Å; S473-D477 PolarHBondContact O-N 2.84Å
474N87.8Confident83.8Confident54 Ų5482.1 Ų82.129%0.28943%0.429SS..Hα-helixtrans-63-35.3-178.4-62.4-5.9000112.6I453 I470 L471 L472 V478I453-N474 HydrophobicContact CD1-CB 3.88Å; I453-N474 WeakPolarHBondContact CD1-O 3.22Å; I453-N474 HydrophobicContact CG1-CB 3.96Å; I470-N474 VanDerWaalsContact O-CG 3.26Å; I470-N474 PolarHBondContact O-N 3.49Å; I470-N474 PolarHBondContact O-OD1 3.29Å; L471-N474 PolarHBondContact O-N 2.95Å; L472-N474 PolarHBondContact O-N 3.19Å; N474-V478 WeakPolarHBondContact O-CG2 3.15Å; N474-V478 PolarHBondContact O-N 2.78Å
475I87.4Confident83.2Confident47 Ų4780.2 Ų80.224%0.24142%0.422CS..Hα-helixtrans-67.4-44177-70.8164.8000110.2F407 I453 L471 L472 S473 V478 M479F407-I475 HydrophobicContact CE1-CD1 4.28Å; F407-I475 HydrophobicContact CZ-CD1 3.98Å; I453-I475 HydrophobicContact CD1-CG1 4.33Å; I453-I475 HydrophobicContact CG2-CG1 4.29Å; L471-I475 WeakPolarHBondContact O-CB 3.29Å; L471-I475 WeakPolarHBondContact O-CD1 3.36Å; L471-I475 WeakPolarHBondContact O-CG1 3.21Å; L471-I475 PolarHBondContact O-N 3.08Å; L472-I475 PolarHBondContact O-N 2.99Å; S473-I475 VanDerWaalsContact C-N 3.29Å; S473-I475 PolarHBondContact O-N 3.1Å; I475-V478 PolarHBondContact O-N 3.24Å; I475-M479 HydrophobicContact CG2-SD 4.04Å; I475-M479 VanDerWaalsContact O-CG 3.29Å; I475-M479 WeakPolarHBondContact O-CG 3.5Å; I475-M479 PolarHBondContact O-N 3.48Å
476L87Confident82.4Confident82 Ų8284.5 Ų84.543%0.42945%0.445SS..Hα-helixtrans-63.3-43177.2-67.3172.5000111.3L472 S473 V478 M479 D480L472-L476 HydrophobicContact CD1-CD1 4.33Å; L472-L476 HydrophobicContact CD1-CG 4.32Å; L472-L476 HydrophobicContact CG-CD1 4.18Å; L472-L476 VanDerWaalsContact O-CG 3.31Å; L472-L476 WeakPolarHBondContact O-CG 3.34Å; L472-L476 PolarHBondContact O-N 3.48Å; S473-L476 PolarHBondContact O-N 3.33Å; S473-L476 VanDerWaalsContact O-N 3.16Å; L476-V478 VanDerWaalsContact C-N 3.31Å; L476-V478 PolarHBondContact O-N 2.92Å; L476-M479 WeakPolarHBondContact O-CB 3.4Å; L476-M479 PolarHBondContact O-N 2.88Å; L476-M479 VanDerWaalsContact O-N 3.09Å; L476-D480 PolarHBondContact O-N 2.84Å
477D90Very high81.8Confident85 Ų8588.5 Ų88.546%0.45547%0.465SS..Hα-helixtrans-59.2-41.9177.6-65.9-25.7000111.7S473 D480 E481S473-D477 VanDerWaalsContact O-CG 3.26Å; S473-D477 PolarHBondContact O-N 2.84Å; D477-D480 PolarHBondContact O-N 3.08Å; D477-E481 WeakPolarHBondContact O-CG 2.76Å; D477-E481 PolarHBondContact O-N 2.9Å
478V90.6Very high81.5Confident17 Ų1790.1 Ų90.110%0.10347%0.47CS..Hα-helixtrans-69.4-33.5176.7173.60000112K449 V450 I453 N474 I475 L476 E482K449-V478 HydrophobicContact CB-CG2 3.91Å; K449-V478 HydrophobicContact CD-CG2 4.47Å; V450-V478 HydrophobicContact CG2-CG1 3.92Å; I453-V478 HydrophobicContact CD1-CG2 3.82Å; N474-V478 WeakPolarHBondContact O-CG2 3.15Å; N474-V478 PolarHBondContact O-N 2.78Å; I475-V478 PolarHBondContact O-N 3.24Å; L476-V478 VanDerWaalsContact C-N 3.31Å; L476-V478 PolarHBondContact O-N 2.92Å; V478-E482 PolarHBondContact O-N 3.15Å
479M84.3Confident81.4Confident108 Ų10889.5 Ų89.553%0.53247%0.473SS..Hα-helixtrans-67.7-39.3176.1-71.9175.86400112I475 L476 E481 E482 S483I475-M479 HydrophobicContact CG2-SD 4.04Å; I475-M479 VanDerWaalsContact O-CG 3.29Å; I475-M479 WeakPolarHBondContact O-CG 3.5Å; I475-M479 PolarHBondContact O-N 3.48Å; L476-M479 WeakPolarHBondContact O-CB 3.4Å; L476-M479 PolarHBondContact O-N 2.88Å; L476-M479 VanDerWaalsContact O-N 3.09Å; M479-E481 VanDerWaalsContact C-N 3.33Å; M479-E482 PolarHBondContact O-N 3.27Å; M479-S483 PolarHBondContact O-N 3.3Å; M479-S483 PolarHBondContact O-OG 3.24Å
480D83.7Confident81.5Confident115 Ų11583.1 Ų83.162%0.61545%0.45SS*.Hα-helixtrans-71.7-27.6-180-73.6-11.7000112.3L476 D477L476-D480 PolarHBondContact O-N 2.84Å; D477-D480 PolarHBondContact O-N 3.08Å
481E75.7Confident81.1Confident116 Ų11683.1 Ų83.154%0.54245%0.452SS..Hα-helixtrans-77.7-22.9176.2-73.1177.6149.800114.2K449 D477 M479K449-E481 VanDerWaalsContact CD-OE2 3.27Å; K449-E481 WeakPolarHBondContact CD-OE2 3.36Å; K449-E481 WeakPolarHBondContact CE-OE2 3.47Å; K449-E481 IonicContact NZ-OE1 2.97Å; K449-E481 PolarHBondContact NZ-OE1 3.09Å; K449-E481 IonicContact NZ-OE2 3.38Å; K449-E481 PolarHBondContact NZ-OE2 2.92Å; D477-E481 WeakPolarHBondContact O-CG 2.76Å; D477-E481 PolarHBondContact O-N 2.9Å; M479-E481 VanDerWaalsContact C-N 3.33Å
482E59.3Low80.6Confident142 Ų14289.9 Ų89.966%0.66449%0.49SS*.  trans-95.8-3.7177.3-68.1-172.4174.300113V478 M479V478-E482 PolarHBondContact O-N 3.15Å; M479-E482 PolarHBondContact O-N 3.27Å
483S49.3Very low80.2Confident150 Ų15088.6 Ų88.6100%1.04949%0.485SS*.  trans-90.70175.5-590000111.8M479M479-S483 PolarHBondContact O-N 3.3Å; M479-S483 PolarHBondContact O-OG 3.24Å

Retrieved 483 of 483 residues in 81.8 ms (Link to these results)