S41A1_PONAB Loading...

Solute carrier family 41 member 1

Na(+)/Mg(2+) ion exchanger that acts as a predominant Mg(2+) efflux system at the plasma membrane. Transporter activity is driven by the inwardly directed electrochemical gradient for Na(+) ions, thus directly depends on the extracellular Na(+) ion concentration set by Na(+)/K(+) pump. Generates circadian cellular Mg(2+) fluxes that feed back to regulate clock-controlled gene expression and metabolism and facilitate higher energetic demands during the day (By similarity). Has a role in regulating the activity of ATP-dependent enzymes, including those operating in Krebs cycle and the electron transport chain (By similarity).

AlphaFold DB , UniProt , Accession Q5R839, Species PONAB (Pongo abelii, Sumatran orangutan), Gene SLC41A1, Length 513 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	38.4	Very low	44.3	Very low	246 Å²	246	147.1 Å²	147.1	100%	1.212	79%	0.791	S	S	*	*				0	121.6	0	-83.8	159.6	118.2	0	0	107.8
2	S	44	Very low	44	Very low	113 Å²	113	147.2 Å²	147.2	79%	0.79	78%	0.782	S	S	*	*			trans	54	95.3	178.5	-91.3	0	0	0	0	118.2
3	S	42	Very low	43.7	Very low	105 Å²	105	148 Å²	148	73%	0.734	79%	0.786	S	S	*	*				53.7	125.1	73.3	73.7	0	0	0	0	113.2
4	K	46	Very low	43.2	Very low	178 Å²	178	149.1 Å²	149.1	77%	0.774	79%	0.792	S	S	*	*			cis	-176.9	149.9	47	-145.1	-179	-172.9	-164	0	110.2
5	P	49.7	Very low	42.8	Very low	121 Å²	121	143.5 Å²	143.5	79%	0.786	78%	0.783	S	S	*	*			trans	-113.3	158.3	160.3	36.9	-26	0	0	0	112.4
6	E	47.9	Very low	42.6	Very low	148 Å²	148	144.1 Å²	144.1	69%	0.692	79%	0.793	S	S	*	*			trans	-166.1	135.5	161.7	-128.2	178.8	136.2	0	0	113
7	P	50.8	Low	42.3	Very low	115 Å²	115	140 Å²	140	75%	0.747	79%	0.792	S	S	*	*			trans	-115.2	167.2	164.7	38.7	-27.3	0	0	0	112.8
8	K	43.6	Very low	42.4	Very low	171 Å²	171	139.6 Å²	139.6	74%	0.743	80%	0.796	S	S	*	*			trans	172.8	115.7	161.3	-98.7	154.8	-174.8	179.4	0	108.9
9	D	40.3	Very low	42.2	Very low	144 Å²	144	138.4 Å²	138.4	77%	0.77	80%	0.797	S	S	*	*				101.3	148.4	76.7	-91.5	-31.9	0	0	0	112.3
10	V	42.2	Very low	42.2	Very low	116 Å²	116	135.6 Å²	135.6	70%	0.703	79%	0.791	S	S	*	*			trans	127.2	103.2	142.3	-178.2	0	0	0	0	117.2
11	H	42.4	Very low	42.1	Very low	161 Å²	161	134.9 Å²	134.9	75%	0.745	79%	0.794	S	S	*	*			trans	62.7	149.6	136.4	-69.3	-34.9	0	0	0	120.9
12	Q	40.8	Very low	42.2	Very low	148 Å²	148	129 Å²	129	69%	0.692	77%	0.774	S	S	*	*			cis	-169.2	141.1	14.4	-125.7	172.8	23.7	0	0	111.4
13	L	40.5	Very low	41.8	Very low	158 Å²	158	130 Å²	130	83%	0.827	78%	0.779	S	S	*	*			trans	60.1	135.9	133.3	-96.1	128.1	0	0	0	126.4
14	N	35.8	Very low	41.4	Very low	164 Å²	164	130.2 Å²	130.2	88%	0.877	78%	0.781	S	S	*	*			trans	-56.8	160.2	175.6	-83.7	-23.2	0	0	0	118.5
15	G	38	Very low	41.1	Very low	64 Å²	64	127.8 Å²	127.8	66%	0.66	79%	0.786	S	S	*	*			trans	156.6	100.8	141.4	0	0	0	0	0	119.4
16	T	39.8	Very low	40.5	Very low	153 Å²	153	130.4 Å²	130.4	94%	0.939	79%	0.794	S	S	*	*			trans	57.2	125.1	135.9	54.5	0	0	0	0	124.2
17	G	36.4	Very low	40.1	Very low	75 Å²	75	126.8 Å²	126.8	77%	0.773	80%	0.796	S	S	*	*			trans	114	125.8	131.4	0	0	0	0	0	119.5
18	P	44.2	Very low	39.5	Very low	133 Å²	133	127.9 Å²	127.9	86%	0.864	80%	0.803	S	S	*	*			trans	-105.5	153.9	-176.4	38.9	-30.6	0	0	0	115.1
19	S	38.8	Very low	39	Very low	116 Å²	116	123.2 Å²	123.2	81%	0.811	80%	0.803	S	S	*	*			trans	170.7	107.5	164.6	167.8	0	0	0	0	108.6
20	A	41.6	Very low	38.9	Very low	83 Å²	83	127.5 Å²	127.5	69%	0.686	81%	0.809	S	S	*	*				100	128	90.7	0	0	0	0	0	114.8
21	S	41.8	Very low	38.6	Very low	120 Å²	120	130.1 Å²	130.1	84%	0.839	81%	0.813	S	S	*	*			trans	111.9	133.6	141.9	-53.3	0	0	0	0	119.1
22	P	40.1	Very low	38.2	Very low	122 Å²	122	128.7 Å²	128.7	79%	0.792	82%	0.819	S	S	*	*			trans	-104.6	164.5	-170.2	41.1	-32.3	0	0	0	113.3
23	C	34.8	Very low	38	Very low	134 Å²	134	130 Å²	130	91%	0.905	83%	0.829	S	S	*	*			trans	-155.3	124.2	160.3	-107.8	0	0	0	0	112.4
24	S	34.3	Very low	37.7	Very low	110 Å²	110	127 Å²	127	77%	0.769	83%	0.827	S	S	*	*			trans	-78.9	148.7	168.5	47.1	0	0	0	0	112.6
25	S	40.1	Very low	37.6	Very low	127 Å²	127	123 Å²	123	89%	0.888	83%	0.825	S	S	*	*			trans	-159.1	119.8	152.5	-49.6	0	0	0	0	111.5
26	D	37.3	Very low	37.2	Very low	176 Å²	176	125.9 Å²	125.9	94%	0.941	83%	0.83	S	S	*	*			trans	-68	160.3	174.3	-79.3	-52.3	0	0	0	115.1
27	G	38.7	Very low	36.9	Very low	72 Å²	72	124.4 Å²	124.4	74%	0.742	83%	0.826	S	S	*	*			trans	165.7	139	150.8	0	0	0	0	0	114.9
28	P	38.8	Very low	36.6	Very low	138 Å²	138	128 Å²	128	90%	0.896	82%	0.823	S	S	*	*				-124.7	164.8	-129.2	36.3	-20.9	0	0	0	117.3
29	G	33.3	Very low	36	Very low	73 Å²	73	131.8 Å²	131.8	75%	0.753	83%	0.826	S	S	*	*			trans	109.6	105.9	137.2	0	0	0	0	0	119.9
30	R	37.2	Very low	35.6	Very low	234 Å²	234	133.3 Å²	133.3	88%	0.883	82%	0.824	S	S	*	*				-176.4	107.6	124.8	-109.9	176.7	169.8	153.9	-0.4	113.9
31	E	35.7	Very low	35.2	Very low	171 Å²	171	132.5 Å²	132.5	80%	0.799	82%	0.824	S	S	*	*			trans	53.9	124.5	142.2	-62.7	179.6	117.1	0	0	123.5
32	P	34.4	Very low	34.7	Very low	132 Å²	132	132.4 Å²	132.4	86%	0.857	82%	0.821	S	S	*	*			trans	-129.2	139.9	142.9	33.5	-18	0	0	0	114.1
33	L	36.6	Very low	34.4	Very low	174 Å²	174	134.3 Å²	134.3	91%	0.911	82%	0.824	S	S	*	*			trans	-103.2	147.5	165.8	-79	153.7	0	0	0	107.8
34	A	35.2	Very low	34.2	Very low	95 Å²	95	132.3 Å²	132.3	79%	0.785	83%	0.826	S	S	*	*			cis	176.3	141.1	-17.9	0	0	0	0	0	104.1
35	G	33.1	Very low	34	Very low	81 Å²	81	131 Å²	131	84%	0.835	82%	0.821	S	S	*	*			trans	154.6	46.6	169	0	0	0	0	0	117.7
36	T	28.7	Very low	33.3	Very low	125 Å²	125	129.1 Å²	129.1	77%	0.767	82%	0.822	S	S	*	*			trans	-73.9	140.3	172.9	-6.3	0	0	0	0	111.9	E38	T36-E38 HydrophobicContact CG2-CG 4.26Å
37	S	33.4	Very low	32.9	Very low	122 Å²	122	126.1 Å²	126.1	85%	0.853	81%	0.81	S	S	*	*			trans	-140.8	94.7	144.7	-163.6	0	0	0	0	108
38	E	30.3	Very low	32.3	Very low	151 Å²	151	131.5 Å²	131.5	71%	0.706	82%	0.816	S	S	*	*			trans	-78.4	134.4	164.6	-74.4	178.2	109.8	0	0	108.9	T36	T36-E38 HydrophobicContact CG2-CG 4.26Å
39	F	31.3	Very low	31.7	Very low	212 Å²	212	129.4 Å²	129.4	93%	0.93	80%	0.801	S	S	*	*			trans	-125.3	105.1	151.9	-141.4	-89	0	0	0	107.8
40	L	31.1	Very low	31.4	Very low	148 Å²	148	132.2 Å²	132.2	78%	0.775	80%	0.803	S	S	*	*			trans	-71	129.6	175.4	-134.1	89.9	0	0	0	109.4
41	G	32.7	Very low	31.1	Very low	65 Å²	65	127.9 Å²	127.9	67%	0.67	80%	0.796	S	S	*	*			trans	-144	125.8	162.8	0	0	0	0	0	108.2
42	P	32	Very low	30.6	Very low	119 Å²	119	125.9 Å²	125.9	77%	0.773	79%	0.786	S	S	*	*			trans	-84.5	126.7	-166.9	33.4	-31.2	0	0	0	110.7
43	D	34.4	Very low	30.3	Very low	161 Å²	161	124.4 Å²	124.4	86%	0.861	78%	0.779	S	S	*	*			trans	164.1	89.7	139.6	-82.7	-15.3	0	0	0	107.6	A45	D43-A45 PolarHBondContact O-N 3.4Å
44	G	28.9	Very low	29.9	Very low	92 Å²	92	125 Å²	125	95%	0.948	77%	0.769	S	S	*	*			trans	-76.1	100.9	179	0	0	0	0	0	111.3
45	A	30.3	Very low	29.8	Very low	82 Å²	82	124.8 Å²	124.8	68%	0.678	77%	0.768	S	S	*	*			trans	-132.1	95.3	151	0	0	0	0	0	106.9	D43 V47	D43-A45 PolarHBondContact O-N 3.4Å; A45-V47 PolarHBondContact O-N 3.19Å
46	G	27	Very low	29.8	Very low	88 Å²	88	127.5 Å²	127.5	91%	0.907	76%	0.763	S	S	*	*			trans	-66.8	98.4	169.8	0	0	0	0	0	108.7
47	V	27.1	Very low	30.1	Very low	113 Å²	113	124.2 Å²	124.2	69%	0.685	75%	0.748	S	S	*	*			trans	-92.3	105.2	168.5	-174.3	0	0	0	0	107	A45 V49	A45-V47 PolarHBondContact O-N 3.19Å; V47-V49 HydrophobicContact CB-CG2 4.2Å; V47-V49 HydrophobicContact CG1-CG2 3.51Å; V47-V49 PolarHBondContact O-N 3.29Å; V47-V49 VanDerWaalsContact O-N 3.15Å
48	E	26.8	Very low	30.1	Very low	186 Å²	186	126.7 Å²	126.7	87%	0.869	74%	0.744	S	S	*	*			trans	-70.5	97.2	165.4	-160.6	172.6	-156.4	0	0	107.2	V50	E48-V50 PolarHBondContact O-N 3.24Å
49	V	27	Very low	30.4	Very low	94 Å²	94	122.1 Å²	122.1	57%	0.57	74%	0.738	S	S	*	*			trans	-89	92.2	-178	177.7	0	0	0	0	108.9	V47 I51	V47-V49 HydrophobicContact CB-CG2 4.2Å; V47-V49 HydrophobicContact CG1-CG2 3.51Å; V47-V49 PolarHBondContact O-N 3.29Å; V47-V49 VanDerWaalsContact O-N 3.15Å; V49-I51 HydrophobicContact CG1-CD1 3.36Å; V49-I51 HydrophobicContact CG1-CG1 3.4Å; V49-I51 PolarHBondContact O-N 2.94Å
50	V	26.8	Very low	30.7	Very low	132 Å²	132	115.4 Å²	115.4	80%	0.8	71%	0.714	S	S	*	*			trans	-73.9	99.7	160.5	177.5	0	0	0	0	107.2	E48	E48-V50 PolarHBondContact O-N 3.24Å
51	I	29.4	Very low	31	Very low	142 Å²	142	117.8 Å²	117.8	73%	0.728	71%	0.712	S	S	*	*			trans	-92	104.5	171	-76.9	157.4	0	0	0	109.2	V49 S53	V49-I51 HydrophobicContact CG1-CD1 3.36Å; V49-I51 HydrophobicContact CG1-CG1 3.4Å; V49-I51 PolarHBondContact O-N 2.94Å; I51-S53 PolarHBondContact O-N 3.07Å
52	E	26.6	Very low	31.3	Very low	130 Å²	130	122 Å²	122	61%	0.607	71%	0.714	S	S	*	*			trans	-62.4	109.1	167	-160.2	-175.7	177.1	0	0	109.2	R54	E52-R54 VanDerWaalsContact C-N 3.27Å; E52-R54 PolarHBondContact O-N 3.47Å; E52-R54 IonicContact OE1-CZ 3.13Å; E52-R54 IonicContact OE1-NE 3.31Å; E52-R54 PolarHBondContact OE1-NE 3.2Å; E52-R54 IonicContact OE1-NH2 3.13Å
53	S	26.9	Very low	31.8	Very low	101 Å²	101	123.1 Å²	123.1	71%	0.706	71%	0.71	S	S	*	*			trans	-73.7	81.2	176.1	-162.7	0	0	0	0	110.2	I51	I51-S53 PolarHBondContact O-N 3.07Å
54	R	29.3	Very low	32.1	Very low	185 Å²	185	119.2 Å²	119.2	70%	0.698	69%	0.688	S	S	*	*			trans	-92.1	9.6	-177	-123.1	177.5	-168.4	-168.4	0.5	114.2	E52	E52-R54 VanDerWaalsContact C-N 3.27Å; E52-R54 PolarHBondContact O-N 3.47Å; E52-R54 IonicContact OE1-CZ 3.13Å; E52-R54 IonicContact OE1-NE 3.31Å; E52-R54 PolarHBondContact OE1-NE 3.2Å; E52-R54 IonicContact OE1-NH2 3.13Å
55	A	32.2	Very low	32.9	Very low	91 Å²	91	118 Å²	118	75%	0.752	67%	0.67	S	S	*	*	S	Bend	trans	-95	-19.1	-166.9	0	0	0	0	0	115.8
56	N	34.8	Very low	33.6	Very low	139 Å²	139	121.1 Å²	121.1	74%	0.743	67%	0.674	S	S	*	*	S	Bend	trans	-99.3	5.3	-178.4	-149.2	23.5	0	0	0	114.6
57	A	33.7	Very low	34.6	Very low	55 Å²	55	124 Å²	124	46%	0.455	67%	0.668	S	S	.	*	S	Bend	trans	-100.9	-0.8	-175.5	0	0	0	0	0	114.6
58	K	34.4	Very low	35.4	Very low	174 Å²	174	126.9 Å²	126.9	76%	0.757	67%	0.674	S	S	*	*	T	Hydrogen-bonded Turn	trans	-89.9	-27.6	179.9	-83.1	-174.4	174.4	-177.2	0	114.2
59	G	34.9	Very low	36	Very low	56 Å²	56	125.9 Å²	125.9	58%	0.577	68%	0.675	S	S	*	*	T	Hydrogen-bonded Turn	trans	-78.3	-25.8	179.4	0	0	0	0	0	114.7
60	V	39.5	Very low	36.4	Very low	70 Å²	70	124.3 Å²	124.3	42%	0.424	68%	0.678	S	S	.	*	T	Hydrogen-bonded Turn	trans	-88.9	-24.6	-179.2	-176.4	0	0	0	0	111.8	E62 L91	V60-E62 VanDerWaalsContact C-N 3.34Å; V60-E62 PolarHBondContact O-N 2.95Å; V60-L91 HydrophobicContact CG1-CD1 3.99Å
61	R	36.9	Very low	37.1	Very low	199 Å²	199	123.1 Å²	123.1	75%	0.751	68%	0.675	S	S	*	*	H	α-helix	trans	-74.4	-19.6	-179.1	-114.8	176	176.6	168.7	-0.9	114.5	A65	R61-A65 WeakPolarHBondContact O-CB 3.32Å; R61-A65 PolarHBondContact O-N 2.74Å
62	E	39.1	Very low	37.4	Very low	152 Å²	152	124.9 Å²	124.9	71%	0.71	68%	0.68	S	S	*	*	H	α-helix	trans	-83.1	-25.8	178.8	-117.6	174	167.2	0	0	112.4	V60	V60-E62 VanDerWaalsContact C-N 3.34Å; V60-E62 PolarHBondContact O-N 2.95Å
63	E	41.6	Very low	37.9	Very low	144 Å²	144	123.5 Å²	123.5	67%	0.673	69%	0.685	S	S	*	*	H	α-helix	trans	-82	-34.3	177.4	-65.4	-171.7	144.1	0	0	112.3
64	D	40.6	Very low	38.3	Very low	78 Å²	78	125.4 Å²	125.4	42%	0.417	69%	0.687	S	S	.	*	H	α-helix	trans	-77.9	-30.1	177.6	-70.5	-27.1	0	0	0	112.9	L66 L67	D64-L66 PolarHBondContact O-N 3.34Å; D64-L67 PolarHBondContact O-N 3.43Å
65	A	45.1	Very low	38.8	Very low	67 Å²	67	124.3 Å²	124.3	55%	0.554	69%	0.69	S	S	*	*	T	Hydrogen-bonded Turn	trans	-69.2	-16.8	176.7	0	0	0	0	0	113.5	R61	R61-A65 WeakPolarHBondContact O-CB 3.32Å; R61-A65 PolarHBondContact O-N 2.74Å
66	L	45.1	Very low	39.1	Very low	147 Å²	147	124.7 Å²	124.7	77%	0.77	69%	0.687	S	S	*	*	T	Hydrogen-bonded Turn	trans	-88.4	-8.7	177.2	-71.2	173.1	0	0	0	113.5	D64	D64-L66 PolarHBondContact O-N 3.34Å
67	L	48.1	Very low	39.1	Very low	150 Å²	150	125.3 Å²	125.3	79%	0.785	69%	0.69	S	S	*	*	T	Hydrogen-bonded Turn	trans	-108.9	-10.9	-176.5	-67.1	175.7	0	0	0	114.7	D64	D64-L67 PolarHBondContact O-N 3.43Å
68	E	44.7	Very low	39.4	Very low	173 Å²	173	130.2 Å²	130.2	81%	0.808	71%	0.709	S	S	*	*			trans	-108.7	4.9	-172.9	-127.9	179.4	174.6	0	0	115.4	G70	E68-G70 PolarHBondContact O-N 2.8Å
69	N	38.9	Very low	39.7	Very low	165 Å²	165	127.4 Å²	127.4	88%	0.882	71%	0.706	S	S	*	*			trans	-81.3	34.7	-173.1	-144	7.9	0	0	0	114.7
70	G	36.4	Very low	39.7	Very low	61 Å²	61	130 Å²	130	63%	0.629	72%	0.715	S	S	*	*			trans	-145.4	70.5	-174.8	0	0	0	0	0	112.9	E68	E68-G70 PolarHBondContact O-N 2.8Å
71	S	41.5	Very low	39.7	Very low	107 Å²	107	133 Å²	133	75%	0.748	73%	0.734	S	S	*	*	S	Bend	trans	168.4	120.1	142.1	-76.1	0	0	0	0	112.4
72	Q	35.7	Very low	39.5	Very low	179 Å²	179	131.4 Å²	131.4	84%	0.836	74%	0.74	S	S	*	*			trans	61.9	106.8	143.7	-68.4	174.2	-7.5	0	0	118.7
73	S	35.8	Very low	39.4	Very low	101 Å²	101	135.1 Å²	135.1	71%	0.706	75%	0.748	S	S	*	*				82.8	110.9	69.2	72.1	0	0	0	0	115.9
74	N	36.1	Very low	39.1	Very low	141 Å²	141	130.8 Å²	130.8	75%	0.754	74%	0.742	S	S	*	*			trans	68.2	123.4	143.7	-76.7	23.1	0	0	0	123.9
75	E	39.1	Very low	39.1	Very low	162 Å²	162	133.3 Å²	133.3	76%	0.757	76%	0.763	S	S	*	*				103.6	118.8	125	-94.6	169.9	106.9	0	0	121.8
76	S	38.6	Very low	38.5	Very low	99 Å²	99	134 Å²	134	69%	0.692	77%	0.769	S	S	*	*			trans	77.2	106.7	138.9	48	0	0	0	0	121.5
77	D	35.8	Very low	38	Very low	151 Å²	151	132.2 Å²	132.2	81%	0.807	77%	0.766	S	S	*	*				31.3	113.2	127.7	-60	-19.2	0	0	0	119.7
78	D	38.8	Very low	37.5	Very low	158 Å²	158	130.9 Å²	130.9	85%	0.845	77%	0.766	S	S	*	*			trans	-160.3	116.7	137.8	-98.9	-29.9	0	0	0	113.1
79	V	42.2	Very low	37.2	Very low	116 Å²	116	127.6 Å²	127.6	70%	0.703	76%	0.762	S	S	*	*			trans	41.1	101.8	138.3	-170.3	0	0	0	0	119.4
80	S	34.6	Very low	37.6	Very low	110 Å²	110	122.9 Å²	122.9	77%	0.769	74%	0.74	S	S	*	*			trans	15.3	103	139.6	52.7	0	0	0	0	119
81	T	38.5	Very low	38.2	Very low	133 Å²	133	125.6 Å²	125.6	82%	0.816	74%	0.74	S	S	*	*			trans	-134	107.7	135.1	-2.1	0	0	0	0	107.7	R83	T81-R83 VanDerWaalsContact C-N 3.27Å; T81-R83 PolarHBondContact O-N 2.94Å
82	D	32.5	Very low	39	Very low	165 Å²	165	128.6 Å²	128.6	88%	0.882	74%	0.739	S	S	*	*			trans	-66.7	84.5	176.7	-165.8	13.6	0	0	0	109.1
83	R	38.1	Very low	40.5	Very low	230 Å²	230	123.2 Å²	123.2	87%	0.868	71%	0.714	S	S	*	*			trans	-95.3	110.9	157.8	-79	-177.1	178.5	167.1	0.9	105.3	T81	T81-R83 VanDerWaalsContact C-N 3.27Å; T81-R83 PolarHBondContact O-N 2.94Å
84	G	34.3	Very low	42.6	Very low	53 Å²	53	122.2 Å²	122.2	55%	0.546	70%	0.704	S	S	.	*	P	Polyproline II helix	trans	-46.3	150.4	172.9	0	0	0	0	0	111.2	A86	G84-A86 PolarHBondContact O-N 3.37Å
85	P	40.6	Very low	44.8	Very low	132 Å²	132	118 Å²	118	86%	0.857	69%	0.686	S	S	*	*	P	Polyproline II helix	trans	-57.4	119.5	-171.2	23.9	-31.1	0	0	0	108.8
86	A	32.9	Very low	46.9	Very low	82 Å²	82	117.9 Å²	117.9	68%	0.678	68%	0.683	S	S	*	*	P	Polyproline II helix	trans	-51	141	168	0	0	0	0	0	108.2	G84	G84-A86 PolarHBondContact O-N 3.37Å
87	P	35.4	Very low	48.9	Very low	109 Å²	109	115 Å²	115	71%	0.708	66%	0.663	S	S	*	*	P	Polyproline II helix	trans	-52.4	136.7	178.2	21.7	-31.4	0	0	0	108.6	S89	P87-S89 PolarHBondContact O-N 2.92Å
88	P	37.4	Very low	51	Low	122 Å²	122	107.9 Å²	107.9	79%	0.792	62%	0.624	S	S	*	*	P	Polyproline II helix	trans	-53.9	121.2	-176.5	21.6	-31.2	0	0	0	108.2
89	S	38.9	Very low	53	Low	103 Å²	103	101.4 Å²	101.4	72%	0.72	60%	0.595	S	S	*	*	P	Polyproline II helix	trans	-52.1	126.1	173.5	52.8	0	0	0	0	107.5	P87 L91	P87-S89 PolarHBondContact O-N 2.92Å; S89-L91 PolarHBondContact O-N 3.33Å
90	P	46.7	Very low	55	Low	66 Å²	66	101.2 Å²	101.2	43%	0.429	59%	0.59	S	S	.	*	P	Polyproline II helix	trans	-53.6	122.6	-179.6	19.4	-29.6	0	0	0	107.6	K92 F374	P90-K92 PolarHBondContact O-N 3.45Å; P90-F374 HydrophobicContact CG-CE2 4.24Å
91	L	48.3	Very low	57.1	Low	118 Å²	118	100.6 Å²	100.6	62%	0.618	57%	0.574	S	S	*	*			trans	-42.2	119.8	177	-80.2	160.4	0	0	0	107.4	V60 S89 E93	V60-L91 HydrophobicContact CG1-CD1 3.99Å; S89-L91 PolarHBondContact O-N 3.33Å; L91-E93 VanDerWaalsContact C-N 3.26Å; L91-E93 PolarHBondContact O-N 3.49Å
92	K	58	Low	59.1	Low	171 Å²	171	95 Å²	95	74%	0.743	54%	0.54	S	S	*	.			trans	-64.7	90.3	-176.5	-79.2	177.8	179.9	169.5	0	108.3	P90 T94	P90-K92 PolarHBondContact O-N 3.45Å; K92-T94 PolarHBondContact O-N 3.47Å
93	E	67.8	Low	61.8	Low	65 Å²	65	90.5 Å²	90.5	30%	0.304	52%	0.516	S	S	.	.			trans	-59.1	128.5	175.1	-67.8	-177.1	143.9	0	0	109.4	L91 I98 R370	L91-E93 VanDerWaalsContact C-N 3.26Å; L91-E93 PolarHBondContact O-N 3.49Å; E93-I98 HydrophobicContact CB-CD1 4.1Å; E93-I98 HydrophobicContact CB-CG1 4Å; E93-R370 IonicContact OE1-NH2 3.25Å; E93-R370 IonicContact OE2-CZ 3.94Å; E93-R370 IonicContact OE2-NH1 3.79Å; E93-R370 IonicContact OE2-NH2 3.86Å; E93-R370 PolarHBondContact OE2-NH2 3.35Å
94	T	80.9	Confident	64.1	Low	80 Å²	80	86.7 Å²	86.7	49%	0.491	51%	0.506	S	S	.	.			trans	-76.5	148.6	176.7	63.1	0	0	0	0	109.4	K92 F96 S97 I98	K92-T94 PolarHBondContact O-N 3.47Å; T94-F96 PolarHBondContact O-N 3.47Å; T94-F96 VanDerWaalsContact O-N 3.14Å; T94-S97 PolarHBondContact O-N 2.95Å; T94-S97 WeakPolarHBondContact OG1-CB 3.46Å; T94-S97 PolarHBondContact OG1-N 2.83Å; T94-I98 WeakPolarHBondContact O-CG1 3.36Å; T94-I98 PolarHBondContact O-N 2.96Å; T94-I98 VanDerWaalsContact O-N 3.07Å
95	S	81.1	Confident	66.5	Low	53 Å²	53	85.3 Å²	85.3	37%	0.371	49%	0.487	S	S	.	.	H	α-helix	trans	-56.3	-31	175.9	-63.9	0	0	0	0	112.5	G99	S95-G99 PolarHBondContact O-N 2.97Å
96	F	82.9	Confident	68.9	Low	160 Å²	160	79.6 Å²	79.6	70%	0.702	45%	0.449	S	S	*	.	H	α-helix	trans	-68.2	-44.2	175.5	-174.6	-100.1	0	0	0	112.3	T94 I98 G99 L100	T94-F96 PolarHBondContact O-N 3.47Å; T94-F96 VanDerWaalsContact O-N 3.14Å; F96-I98 PolarHBondContact O-N 2.77Å; F96-G99 PolarHBondContact O-N 3Å; F96-L100 HydrophobicContact CE1-CD2 4.46Å; F96-L100 WeakPolarHBondContact O-CB 3.41Å; F96-L100 PolarHBondContact O-N 3.25Å
97	S	81.8	Confident	71.7	Confident	39 Å²	39	78 Å²	78	27%	0.273	43%	0.428	S	S	.	.	H	α-helix	trans	-60.3	-46.7	175.7	-173	0	0	0	0	111.3	T94 G99 L100 Q101	T94-S97 PolarHBondContact O-N 2.95Å; T94-S97 WeakPolarHBondContact OG1-CB 3.46Å; T94-S97 PolarHBondContact OG1-N 2.83Å; S97-G99 VanDerWaalsContact C-N 3.34Å; S97-G99 PolarHBondContact O-N 3.17Å; S97-L100 PolarHBondContact O-N 2.98Å; S97-Q101 WeakPolarHBondContact O-CB 3.29Å; S97-Q101 WeakPolarHBondContact O-CG 3.46Å; S97-Q101 PolarHBondContact O-N 2.77Å; S97-Q101 PolarHBondContact OG-NE2 2.86Å
98	I	78.4	Confident	74.4	Confident	0 Å²	0	75.7 Å²	75.7	0%	0	41%	0.41	C	S	.	.	H	α-helix	trans	-60.2	-46.4	177.1	-59.3	170.1	0	0	0	110.1	E93 T94 F96 L100 Q101 V102 V411	E93-I98 HydrophobicContact CB-CD1 4.1Å; E93-I98 HydrophobicContact CB-CG1 4Å; T94-I98 WeakPolarHBondContact O-CG1 3.36Å; T94-I98 PolarHBondContact O-N 2.96Å; T94-I98 VanDerWaalsContact O-N 3.07Å; F96-I98 PolarHBondContact O-N 2.77Å; I98-L100 PolarHBondContact O-N 3.16Å; I98-Q101 PolarHBondContact O-N 3.39Å; I98-V102 HydrophobicContact CG2-CG2 4.41Å; I98-V102 WeakPolarHBondContact O-CG2 3.49Å; I98-V102 PolarHBondContact O-N 3.09Å; I98-V411 HydrophobicContact CB-CG1 4.49Å; I98-V411 HydrophobicContact CG2-CB 4.34Å; I98-V411 HydrophobicContact CG2-CG1 4.08Å
99	G	82.1	Confident	76.9	Confident	22 Å²	22	70 Å²	70	23%	0.227	37%	0.374	C	S	.	.	H	α-helix	trans	-60.9	-46.1	-179.9	0	0	0	0	0	112.5	S95 F96 S97 V102 L103	S95-G99 PolarHBondContact O-N 2.97Å; F96-G99 PolarHBondContact O-N 3Å; S97-G99 VanDerWaalsContact C-N 3.34Å; S97-G99 PolarHBondContact O-N 3.17Å; G99-V102 PolarHBondContact O-N 3.25Å; G99-L103 WeakPolarHBondContact O-CB 3.49Å; G99-L103 PolarHBondContact O-N 3.41Å
100	L	83.6	Confident	79.6	Confident	113 Å²	113	65.2 Å²	65.2	59%	0.592	34%	0.34	S	S	*	.	H	α-helix	trans	-66.3	-39.9	179.8	-173	63.8	0	0	0	112.1	F96 S97 I98	F96-L100 HydrophobicContact CE1-CD2 4.46Å; F96-L100 WeakPolarHBondContact O-CB 3.41Å; F96-L100 PolarHBondContact O-N 3.25Å; S97-L100 PolarHBondContact O-N 2.98Å; I98-L100 PolarHBondContact O-N 3.16Å
101	Q	79	Confident	81.8	Confident	96 Å²	96	66.4 Å²	66.4	45%	0.449	34%	0.339	S	S	.	.	H	α-helix	trans	-65	-38.3	177.2	-73.1	172	6.1	0	0	112.3	S97 I98 P105	S97-Q101 WeakPolarHBondContact O-CB 3.29Å; S97-Q101 WeakPolarHBondContact O-CG 3.46Å; S97-Q101 PolarHBondContact O-N 2.77Å; S97-Q101 PolarHBondContact OG-NE2 2.86Å; I98-Q101 PolarHBondContact O-N 3.39Å; Q101-P105 VanDerWaalsContact O-CD 3.26Å; Q101-P105 WeakPolarHBondContact O-CD 3.37Å; Q101-P105 VanDerWaalsContact O-CG 3.31Å; Q101-P105 WeakPolarHBondContact O-CG 3.4Å
102	V	80.8	Confident	84	Confident	16 Å²	16	61.2 Å²	61.2	10%	0.097	31%	0.314	C	S	.	.	H	α-helix	trans	-86.1	-27	-177.2	178.5	0	0	0	0	112.7	I98 G99 F104 P105 F106 V366 L412 L415	I98-V102 HydrophobicContact CG2-CG2 4.41Å; I98-V102 WeakPolarHBondContact O-CG2 3.49Å; I98-V102 PolarHBondContact O-N 3.09Å; G99-V102 PolarHBondContact O-N 3.25Å; V102-F104 PolarHBondContact O-N 2.73Å; V102-P105 WeakPolarHBondContact O-CB 3.49Å; V102-P105 WeakPolarHBondContact O-CD 2.89Å; V102-F106 HydrophobicContact CG1-CB 4.28Å; V102-F106 WeakPolarHBondContact O-CB 3.31Å; V102-F106 PolarHBondContact O-N 3.06Å; V102-V366 HydrophobicContact CG2-CG1 4.34Å; V102-L412 HydrophobicContact CG1-CD2 3.76Å; V102-L412 HydrophobicContact CG2-CD2 4.41Å; V102-L415 HydrophobicContact CG1-CD2 4.06Å
103	L	87.9	Confident	85.7	Confident	70 Å²	70	53.1 Å²	53.1	37%	0.366	28%	0.278	S	S	.	.	H	α-helix	trans	-57.6	-51	-172.2	176.9	63.8	0	0	0	113.8	G99 F106 L107 L415	G99-L103 WeakPolarHBondContact O-CB 3.49Å; G99-L103 PolarHBondContact O-N 3.41Å; L103-F106 PolarHBondContact O-N 3.47Å; L103-L107 HydrophobicContact CD1-CD1 4.06Å; L103-L107 HydrophobicContact CD1-CG 4.22Å; L103-L107 HydrophobicContact CG-CD1 4.28Å; L103-L107 WeakPolarHBondContact O-CG 3.28Å; L103-L107 PolarHBondContact O-N 3.17Å; L103-L415 HydrophobicContact CD1-CD1 3.61Å
104	F	87.1	Confident	87	Confident	151 Å²	151	50.1 Å²	50.1	66%	0.662	26%	0.264	S	S	*	.	H	α-helix	trans	-67	-50.7	-178.2	176.1	-91.1	0	0	0	112.4	V102 F106 L107 L108	V102-F104 PolarHBondContact O-N 2.73Å; F104-F106 VanDerWaalsContact C-N 3.27Å; F104-F106 PolarHBondContact O-N 2.73Å; F104-L107 PolarHBondContact O-N 3.42Å; F104-L108 PolarHBondContact O-N 2.93Å
105	P	85.6	Confident	87.7	Confident	23 Å²	23	47.7 Å²	47.7	15%	0.149	25%	0.253	C	S	.	.	H	α-helix	trans	-42.9	-51	165.3	-40.6	44.9	0	0	0	114.6	Q101 V102 L108 A109 P256	Q101-P105 VanDerWaalsContact O-CD 3.26Å; Q101-P105 WeakPolarHBondContact O-CD 3.37Å; Q101-P105 VanDerWaalsContact O-CG 3.31Å; Q101-P105 WeakPolarHBondContact O-CG 3.4Å; V102-P105 WeakPolarHBondContact O-CB 3.49Å; V102-P105 WeakPolarHBondContact O-CD 2.89Å; P105-L108 PolarHBondContact O-N 2.95Å; P105-A109 WeakPolarHBondContact O-CB 3.25Å; P105-A109 PolarHBondContact O-N 2.81Å; P105-P256 HydrophobicContact CB-CB 3.9Å; P105-P256 HydrophobicContact CB-CG 3.33Å; P105-P256 HydrophobicContact CG-CG 3.88Å
106	F	89.6	Confident	88.4	Confident	13 Å²	13	45.2 Å²	45.2	6%	0.057	24%	0.235	C	C	.	.	H	α-helix	trans	-64.3	-44.4	-176.7	169.2	-92.7	0	0	0	112.4	V102 L103 F104 G110 V359 L363 L415 G419 F423	V102-F106 HydrophobicContact CG1-CB 4.28Å; V102-F106 WeakPolarHBondContact O-CB 3.31Å; V102-F106 PolarHBondContact O-N 3.06Å; L103-F106 PolarHBondContact O-N 3.47Å; F104-F106 VanDerWaalsContact C-N 3.27Å; F104-F106 PolarHBondContact O-N 2.73Å; F106-G110 PolarHBondContact O-N 3.41Å; F106-V359 HydrophobicContact CE2-CG1 3.51Å; F106-V359 HydrophobicContact CZ-CG1 3.87Å; F106-L363 HydrophobicContact CD2-CD2 3.58Å; F106-L363 HydrophobicContact CD2-CG 4.09Å; F106-L363 HydrophobicContact CE2-CD1 3.94Å; F106-L363 HydrophobicContact CE2-CD2 3.71Å; F106-L363 HydrophobicContact CE2-CG 3.88Å; F106-L415 HydrophobicContact CB-CD2 3.71Å; F106-L415 HydrophobicContact CD1-CD1 4.05Å; F106-L415 HydrophobicContact CD1-CD2 3.58Å; F106-L415 HydrophobicContact CD1-CG 3.68Å; F106-L415 HydrophobicContact CD2-CD2 3.71Å; F106-L415 HydrophobicContact CD2-CG 4.21Å; F106-L415 HydrophobicContact CE1-CD1 4.13Å; F106-L415 HydrophobicContact CE1-CD2 4.07Å; F106-L415 HydrophobicContact CE1-CG 3.67Å; F106-L415 HydrophobicContact CE2-CD2 4.14Å; F106-L415 HydrophobicContact CE2-CG 4.16Å; F106-L415 HydrophobicContact CG-CD2 3.38Å; F106-L415 HydrophobicContact CG-CG 3.96Å; F106-L415 HydrophobicContact CZ-CD2 4.33Å; F106-L415 HydrophobicContact CZ-CG 3.92Å; F106-G419 VanDerWaalsContact CE1-CA 3.49Å; F106-F423 HydrophobicContact CD1-CZ 4.32Å; F106-F423 AromaticContact CE1-CE2 3.93Å; F106-F423 HydrophobicContact CE1-CE2 3.93Å; F106-F423 AromaticContact CE1-CZ 3.8Å; F106-F423 HydrophobicContact CE1-CZ 3.8Å; F106-F423 AromaticContact CZ-CE2 3.88Å; F106-F423 HydrophobicContact CZ-CE2 3.88Å; F106-F423 HydrophobicContact CZ-CZ 4.2Å
107	L	92.9	Very high	88.9	Confident	47 Å²	47	37.6 Å²	37.6	25%	0.246	20%	0.202	C	C	.	.	H	α-helix	trans	-64.9	-43.7	177.2	-72	175.2	0	0	0	111.6	L103 F104 G110 F111 F423	L103-L107 HydrophobicContact CD1-CD1 4.06Å; L103-L107 HydrophobicContact CD1-CG 4.22Å; L103-L107 HydrophobicContact CG-CD1 4.28Å; L103-L107 WeakPolarHBondContact O-CG 3.28Å; L103-L107 PolarHBondContact O-N 3.17Å; F104-L107 PolarHBondContact O-N 3.42Å; L107-G110 PolarHBondContact O-N 3.07Å; L107-F111 HydrophobicContact CB-CE2 4.35Å; L107-F111 WeakPolarHBondContact O-CD2 3.39Å; L107-F111 PolarHBondContact O-N 3.23Å; L107-F423 HydrophobicContact CD2-CE1 4.1Å; L107-F423 HydrophobicContact CD2-CZ 4.21Å
108	L	91.5	Very high	89.6	Confident	61 Å²	61	36.7 Å²	36.7	32%	0.319	19%	0.194	S	C	.	.	H	α-helix	trans	-60.8	-47.9	177.7	178.8	62.2	0	0	0	111.4	F104 P105 G110 F111 G112 P256 I257 S260	F104-L108 PolarHBondContact O-N 2.93Å; P105-L108 PolarHBondContact O-N 2.95Å; L108-G110 VanDerWaalsContact C-N 3.34Å; L108-G110 PolarHBondContact O-N 3.49Å; L108-F111 PolarHBondContact O-N 3.41Å; L108-G112 PolarHBondContact O-N 3.41Å; L108-G112 VanDerWaalsContact O-N 3.14Å; L108-P256 HydrophobicContact CD2-CB 4.41Å; L108-I257 HydrophobicContact CD2-CG1 3.86Å; L108-S260 WeakPolarHBondContact O-CB 3.48Å
109	A	90.8	Very high	90.4	Very high	4 Å²	4	38.2 Å²	38.2	3%	0.033	20%	0.203	C	C	.	.	H	α-helix	trans	-57.7	-48	174.8	0	0	0	0	0	111.2	P105 F111 G112 T113 A259	P105-A109 WeakPolarHBondContact O-CB 3.25Å; P105-A109 PolarHBondContact O-N 2.81Å; A109-F111 PolarHBondContact O-N 3.42Å; A109-G112 PolarHBondContact O-N 2.98Å; A109-G112 VanDerWaalsContact O-N 3.16Å; A109-T113 WeakPolarHBondContact O-CG2 3.47Å; A109-T113 PolarHBondContact O-N 2.99Å; A109-A259 HydrophobicContact CB-CB 3.77Å
110	G	93.8	Very high	91	Very high	1 Å²	1	37.2 Å²	37.2	1%	0.01	19%	0.192	C	C	.	.	H	α-helix	trans	-61.6	-43.1	178.9	0	0	0	0	0	113.8	F106 L107 L108 G112 T113 V114 F423	F106-G110 PolarHBondContact O-N 3.41Å; L107-G110 PolarHBondContact O-N 3.07Å; L108-G110 VanDerWaalsContact C-N 3.34Å; L108-G110 PolarHBondContact O-N 3.49Å; G110-G112 VanDerWaalsContact C-N 3.29Å; G110-G112 PolarHBondContact O-N 2.87Å; G110-T113 WeakPolarHBondContact CA-OG1 3.44Å; G110-T113 PolarHBondContact O-N 2.99Å; G110-T113 VanDerWaalsContact O-N 3.11Å; G110-T113 PolarHBondContact O-OG1 3.27Å; G110-V114 WeakPolarHBondContact O-CG2 3.39Å; G110-V114 PolarHBondContact O-N 3.32Å; G110-F423 VanDerWaalsContact CA-CZ 3.47Å
111	F	94.4	Very high	91.5	Very high	92 Å²	92	32.3 Å²	32.3	40%	0.404	17%	0.167	S	C	.	.	H	α-helix	trans	-62.5	-35.7	174.2	-75.6	-58.9	0	0	0	112.7	L107 L108 A109 V114 A115 V422 T426	L107-F111 HydrophobicContact CB-CE2 4.35Å; L107-F111 WeakPolarHBondContact O-CD2 3.39Å; L107-F111 PolarHBondContact O-N 3.23Å; L108-F111 PolarHBondContact O-N 3.41Å; A109-F111 PolarHBondContact O-N 3.42Å; F111-V114 PolarHBondContact O-N 2.88Å; F111-A115 PolarHBondContact O-N 2.92Å; F111-V422 HydrophobicContact CE1-CG1 4.34Å; F111-V422 HydrophobicContact CZ-CG1 3.94Å; F111-T426 HydrophobicContact CD1-CG2 4.38Å; F111-T426 HydrophobicContact CE1-CG2 4.18Å
112	G	93.4	Very high	92.2	Very high	9 Å²	9	32.4 Å²	32.4	9%	0.093	17%	0.169	C	C	.	.	H	α-helix	trans	-62.9	-41	172.1	0	0	0	0	0	112.7	L108 A109 G110 A115 A116 S260	L108-G112 PolarHBondContact O-N 3.41Å; L108-G112 VanDerWaalsContact O-N 3.14Å; A109-G112 PolarHBondContact O-N 2.98Å; A109-G112 VanDerWaalsContact O-N 3.16Å; G110-G112 VanDerWaalsContact C-N 3.29Å; G110-G112 PolarHBondContact O-N 2.87Å; G112-A115 PolarHBondContact O-N 3.42Å; G112-A116 PolarHBondContact O-N 2.9Å; G112-S260 WeakPolarHBondContact CA-O 3.38Å
113	T	93.9	Very high	92.9	Very high	0 Å²	0	31.9 Å²	31.9	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-68.2	-34.9	175.3	66.1	0	0	0	0	112.7	A109 G110 A116 G117 D263 P354	A109-T113 WeakPolarHBondContact O-CG2 3.47Å; A109-T113 PolarHBondContact O-N 2.99Å; G110-T113 WeakPolarHBondContact CA-OG1 3.44Å; G110-T113 PolarHBondContact O-N 2.99Å; G110-T113 VanDerWaalsContact O-N 3.11Å; G110-T113 PolarHBondContact O-OG1 3.27Å; T113-A116 PolarHBondContact O-N 2.92Å; T113-G117 PolarHBondContact O-N 3.1Å; T113-D263 WeakPolarHBondContact CG2-OD2 2.88Å; T113-P354 WeakPolarHBondContact CB-O 3.39Å
114	V	95.5	Very high	93.2	Very high	2 Å²	2	29 Å²	29	1%	0.012	15%	0.151	C	C	.	.	H	α-helix	trans	-64.2	-46	172.7	170.9	0	0	0	0	110.1	G110 F111 A116 G117 M118 V355 F423 T426 I427	G110-V114 WeakPolarHBondContact O-CG2 3.39Å; G110-V114 PolarHBondContact O-N 3.32Å; F111-V114 PolarHBondContact O-N 2.88Å; V114-A116 VanDerWaalsContact C-N 3.3Å; V114-A116 PolarHBondContact O-N 3.02Å; V114-G117 WeakPolarHBondContact O-CA 3.48Å; V114-G117 PolarHBondContact O-N 3.44Å; V114-G117 VanDerWaalsContact O-N 3.11Å; V114-M118 WeakPolarHBondContact O-CG 3.17Å; V114-M118 PolarHBondContact O-N 3.01Å; V114-V355 HydrophobicContact CB-CG2 4.33Å; V114-V355 HydrophobicContact CG2-CG1 4.43Å; V114-V355 HydrophobicContact CG2-CG2 3.76Å; V114-F423 HydrophobicContact CG2-CB 3.64Å; V114-F423 HydrophobicContact CG2-CD1 4.15Å; V114-F423 HydrophobicContact CG2-CG 4.06Å; V114-T426 HydrophobicContact CG1-CG2 4.1Å; V114-I427 HydrophobicContact CG1-CG1 3.82Å
115	A	95.5	Very high	93.5	Very high	30 Å²	30	26 Å²	26	25%	0.248	14%	0.139	C	C	.	.	H	α-helix	trans	-60.5	-40.3	175.7	0	0	0	0	0	111.8	F111 G112 M118 V119 L264	F111-A115 PolarHBondContact O-N 2.92Å; G112-A115 PolarHBondContact O-N 3.42Å; A115-M118 PolarHBondContact O-N 2.9Å; A115-V119 WeakPolarHBondContact O-CG2 3.24Å; A115-V119 PolarHBondContact O-N 3.34Å; A115-L264 HydrophobicContact CB-CD1 4.01Å; A115-L264 HydrophobicContact CB-CD2 4.08Å
116	A	95	Very high	93.9	Very high	0 Å²	0	29 Å²	29	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-62.7	-43.6	172.3	0	0	0	0	0	111.7	G112 T113 V114 M118 V119 L120 D263 L267 P354	G112-A116 PolarHBondContact O-N 2.9Å; T113-A116 PolarHBondContact O-N 2.92Å; V114-A116 VanDerWaalsContact C-N 3.3Å; V114-A116 PolarHBondContact O-N 3.02Å; A116-M118 VanDerWaalsContact C-N 3.34Å; A116-M118 PolarHBondContact O-N 3.05Å; A116-V119 PolarHBondContact O-N 2.75Å; A116-V119 VanDerWaalsContact O-N 3.16Å; A116-L120 PolarHBondContact O-N 2.97Å; A116-D263 HydrophobicContact CB-CB 3.74Å; A116-L267 HydrophobicContact CB-CD2 4.42Å; A116-L267 WeakPolarHBondContact O-CD2 3.49Å; A116-P354 HydrophobicContact CB-CB 4.08Å
117	G	95.3	Very high	94.1	Very high	0 Å²	0	31.8 Å²	31.8	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-54.1	-47.5	172	0	0	0	0	0	112.7	T113 V114 V119 L120 D121 V351	T113-G117 PolarHBondContact O-N 3.1Å; V114-G117 WeakPolarHBondContact O-CA 3.48Å; V114-G117 PolarHBondContact O-N 3.44Å; V114-G117 VanDerWaalsContact O-N 3.11Å; G117-V119 VanDerWaalsContact C-N 3.33Å; G117-V119 PolarHBondContact O-N 3.07Å; G117-L120 WeakPolarHBondContact O-CB 3.45Å; G117-L120 PolarHBondContact O-N 3.33Å; G117-L120 VanDerWaalsContact O-N 3.12Å; G117-D121 WeakPolarHBondContact O-CB 3.28Å; G117-D121 PolarHBondContact O-N 3.33Å; G117-V351 WeakPolarHBondContact CA-O 3.32Å; G117-V351 WeakPolarHBondContact O-CA 3.27Å
118	M	94.8	Very high	94.2	Very high	21 Å²	21	29.5 Å²	29.5	10%	0.103	15%	0.148	C	C	.	.	H	α-helix	trans	-63.2	-38.3	177	-65	-59.3	-55.5	0	0	112.3	V114 A115 A116 L120 D121 I122 V351 M430	V114-M118 WeakPolarHBondContact O-CG 3.17Å; V114-M118 PolarHBondContact O-N 3.01Å; A115-M118 PolarHBondContact O-N 2.9Å; A116-M118 VanDerWaalsContact C-N 3.34Å; A116-M118 PolarHBondContact O-N 3.05Å; M118-L120 VanDerWaalsContact C-N 3.35Å; M118-D121 PolarHBondContact O-N 3.47Å; M118-I122 VanDerWaalsContact O-CG1 3.32Å; M118-I122 WeakPolarHBondContact O-CG1 3.32Å; M118-I122 PolarHBondContact O-N 2.85Å; M118-I122 VanDerWaalsContact O-N 3.11Å; M118-V351 HydrophobicContact SD-CG2 3.69Å; M118-M430 HydrophobicContact CE-CB 3.89Å; M118-M430 HydrophobicContact CE-CE 4.36Å; M118-M430 HydrophobicContact CG-CE 3.87Å; M118-M430 HydrophobicContact CG-SD 4.25Å; M118-M430 HydrophobicContact SD-CB 4.11Å
119	V	95.8	Very high	94.3	Very high	32 Å²	32	26.6 Å²	26.6	19%	0.194	13%	0.133	C	C	.	.	H	α-helix	trans	-62.9	-44.8	172.8	171.8	0	0	0	0	110.1	A115 A116 G117 D121 I122 V123 L264 L267	A115-V119 WeakPolarHBondContact O-CG2 3.24Å; A115-V119 PolarHBondContact O-N 3.34Å; A116-V119 PolarHBondContact O-N 2.75Å; A116-V119 VanDerWaalsContact O-N 3.16Å; G117-V119 VanDerWaalsContact C-N 3.33Å; G117-V119 PolarHBondContact O-N 3.07Å; V119-D121 VanDerWaalsContact C-N 3.29Å; V119-D121 PolarHBondContact O-N 3.15Å; V119-I122 PolarHBondContact O-N 2.75Å; V119-V123 HydrophobicContact CG1-CG1 4.08Å; V119-V123 VanDerWaalsContact O-CG1 3.25Å; V119-V123 WeakPolarHBondContact O-CG1 3.46Å; V119-V123 VanDerWaalsContact O-CG2 3.23Å; V119-V123 WeakPolarHBondContact O-CG2 3.41Å; V119-V123 PolarHBondContact O-N 3.31Å; V119-L264 HydrophobicContact CG2-CD1 3.73Å; V119-L267 HydrophobicContact CB-CD2 4.11Å; V119-L267 HydrophobicContact CG1-CD2 4.04Å; V119-L267 HydrophobicContact CG1-CG 4.02Å
120	L	95.2	Very high	94.4	Very high	0 Å²	0	32 Å²	32	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-60.6	-40.8	179.1	-165.6	49.6	0	0	0	111.6	A116 G117 M118 I122 V123 Q124 F129 F136 V139 L267 L337 A350 P354	A116-L120 PolarHBondContact O-N 2.97Å; G117-L120 WeakPolarHBondContact O-CB 3.45Å; G117-L120 PolarHBondContact O-N 3.33Å; G117-L120 VanDerWaalsContact O-N 3.12Å; M118-L120 VanDerWaalsContact C-N 3.35Å; L120-I122 PolarHBondContact O-N 3.1Å; L120-V123 HydrophobicContact CD1-CG2 4.16Å; L120-V123 WeakPolarHBondContact O-CG2 3.2Å; L120-V123 PolarHBondContact O-N 3.32Å; L120-Q124 WeakPolarHBondContact O-CB 3.44Å; L120-Q124 WeakPolarHBondContact O-CG 3.42Å; L120-Q124 PolarHBondContact O-N 2.85Å; L120-F129 HydrophobicContact CD1-CE1 4.47Å; L120-F136 HydrophobicContact CD1-CD1 4.39Å; L120-F136 HydrophobicContact CD1-CE1 4.29Å; L120-V139 HydrophobicContact CD1-CG2 4.22Å; L120-V139 HydrophobicContact CD2-CG1 4.22Å; L120-L267 HydrophobicContact CB-CD2 3.67Å; L120-L267 HydrophobicContact CD1-CD1 4.08Å; L120-L267 HydrophobicContact CD1-CD2 4.34Å; L120-L267 HydrophobicContact CG-CD2 4.44Å; L120-L337 HydrophobicContact CD2-CD2 4.26Å; L120-A350 WeakPolarHBondContact CD2-O 3.43Å; L120-A350 HydrophobicContact CG-CB 4.08Å; L120-P354 HydrophobicContact CB-CG 4.48Å; L120-P354 HydrophobicContact CD2-CG 3.92Å
121	D	94.1	Very high	94.3	Very high	10 Å²	10	37.5 Å²	37.5	5%	0.053	18%	0.181	C	C	.	.	H	α-helix	trans	-64.9	-35.8	178.4	-170.8	44.4	0	0	0	113.1	G117 M118 V119 Q124 H125 V351 G433 H434	G117-D121 WeakPolarHBondContact O-CB 3.28Å; G117-D121 PolarHBondContact O-N 3.33Å; M118-D121 PolarHBondContact O-N 3.47Å; V119-D121 VanDerWaalsContact C-N 3.29Å; V119-D121 PolarHBondContact O-N 3.15Å; D121-Q124 WeakPolarHBondContact O-CG 3.18Å; D121-Q124 PolarHBondContact OD1-NE2 3.48Å; D121-H125 PolarHBondContact O-CE1 3.21Å; D121-H125 PolarHBondContact O-ND1 3.29Å; D121-V351 HydrophobicContact CB-CB 4.05Å; D121-V351 HydrophobicContact CB-CG2 4.36Å; D121-G433 PolarHBondContact OD2-N 3.16Å; D121-H434 IonicContact OD1-CD2 3.77Å
122	I	93.7	Very high	94.3	Very high	99 Å²	99	33.1 Å²	33.1	51%	0.508	16%	0.162	S	C	.	.	H	α-helix	trans	-74.1	-46	175.6	-67.1	164.6	0	0	0	110.6	M118 V119 L120 H125	M118-I122 VanDerWaalsContact O-CG1 3.32Å; M118-I122 WeakPolarHBondContact O-CG1 3.32Å; M118-I122 PolarHBondContact O-N 2.85Å; M118-I122 VanDerWaalsContact O-N 3.11Å; V119-I122 PolarHBondContact O-N 2.75Å; L120-I122 PolarHBondContact O-N 3.1Å; I122-H125 PolarHBondContact O-N 2.83Å
123	V	95	Very high	94.3	Very high	4 Å²	4	34.3 Å²	34.3	2%	0.024	17%	0.168	C	C	.	.	H	α-helix	trans	-79.7	-21.2	-170.5	-56	0	0	0	0	112.9	V119 L120 H125 W126 F129 S271	V119-V123 HydrophobicContact CG1-CG1 4.08Å; V119-V123 VanDerWaalsContact O-CG1 3.25Å; V119-V123 WeakPolarHBondContact O-CG1 3.46Å; V119-V123 VanDerWaalsContact O-CG2 3.23Å; V119-V123 WeakPolarHBondContact O-CG2 3.41Å; V119-V123 PolarHBondContact O-N 3.31Å; L120-V123 HydrophobicContact CD1-CG2 4.16Å; L120-V123 WeakPolarHBondContact O-CG2 3.2Å; L120-V123 PolarHBondContact O-N 3.32Å; V123-H125 PolarHBondContact O-N 2.88Å; V123-H125 VanDerWaalsContact O-N 3.12Å; V123-W126 HydrophobicContact CB-CD2 4.18Å; V123-W126 HydrophobicContact CB-CE3 4.38Å; V123-W126 HydrophobicContact CB-CG 4.43Å; V123-W126 HydrophobicContact CG1-CD2 4.13Å; V123-W126 HydrophobicContact CG1-CE3 4.23Å; V123-W126 HydrophobicContact CG1-CH2 4.17Å; V123-W126 HydrophobicContact CG1-CZ2 4.03Å; V123-W126 HydrophobicContact CG1-CZ3 4.26Å; V123-W126 VanDerWaalsContact O-CB 3.28Å; V123-W126 WeakPolarHBondContact O-CB 3.41Å; V123-W126 PolarHBondContact O-N 3Å; V123-F129 HydrophobicContact CB-CD2 4.14Å; V123-F129 HydrophobicContact CB-CE2 3.79Å; V123-F129 HydrophobicContact CB-CZ 4.21Å; V123-F129 HydrophobicContact CG2-CD2 4.27Å; V123-F129 HydrophobicContact CG2-CE1 4.09Å; V123-F129 HydrophobicContact CG2-CE2 3.75Å; V123-F129 HydrophobicContact CG2-CZ 3.64Å; V123-F129 WeakPolarHBondContact O-CB 3.45Å; V123-F129 WeakPolarHBondContact O-CD2 3.39Å; V123-F129 WeakPolarHBondContact O-CG 3.16Å; V123-S271 WeakPolarHBondContact CG2-OG 3.29Å
124	Q	93.9	Very high	94.3	Very high	11 Å²	11	35.6 Å²	35.6	5%	0.051	17%	0.174	C	C	.	.	T	Hydrogen-bonded Turn	trans	-56.9	-26.7	173.3	59.2	165	-33.7	0	0	112.5	L120 D121 F136 V341 A347 A350	L120-Q124 WeakPolarHBondContact O-CB 3.44Å; L120-Q124 WeakPolarHBondContact O-CG 3.42Å; L120-Q124 PolarHBondContact O-N 2.85Å; D121-Q124 WeakPolarHBondContact O-CG 3.18Å; D121-Q124 PolarHBondContact OD1-NE2 3.48Å; Q124-F136 HydrophobicContact CB-CE1 3.86Å; Q124-F136 HydrophobicContact CB-CZ 3.74Å; Q124-V341 HydrophobicContact CB-CG1 4.06Å; Q124-A347 PolarHBondContact NE2-O 2.89Å; Q124-A347 VanDerWaalsContact NE2-O 3.1Å; Q124-A347 PolarHBondContact OE1-O 3.24Å; Q124-A350 HydrophobicContact CG-CB 4.34Å; Q124-A350 VanDerWaalsContact NE2-CB 3.34Å
125	H	92.9	Very high	94.4	Very high	88 Å²	88	35.5 Å²	35.5	41%	0.407	17%	0.173	S	C	.	.	T	Hydrogen-bonded Turn	trans	-86.3	-3.9	177.8	-59.1	100.6	0	0	0	113.7	D121 I122 V123 H434	D121-H125 PolarHBondContact O-CE1 3.21Å; D121-H125 PolarHBondContact O-ND1 3.29Å; I122-H125 PolarHBondContact O-N 2.83Å; V123-H125 PolarHBondContact O-N 2.88Å; V123-H125 VanDerWaalsContact O-N 3.12Å; H125-H434 AromaticContact CE1-CD2 3.78Å; H125-H434 AromaticContact CE1-NE2 3.21Å; H125-H434 PolarHBondContact CE1-NE2 3.42Å; H125-H434 AromaticContact NE2-NE2 3.72Å
126	W	94.9	Very high	94.4	Very high	84 Å²	84	34.3 Å²	34.3	32%	0.318	16%	0.162	S	C	.	.	S	Bend	trans	-76.1	146.3	177.9	-68.3	9.4	0	0	0	110.9	V123 V128 F129 Q130 W275	V123-W126 HydrophobicContact CB-CD2 4.18Å; V123-W126 HydrophobicContact CB-CE3 4.38Å; V123-W126 HydrophobicContact CB-CG 4.43Å; V123-W126 HydrophobicContact CG1-CD2 4.13Å; V123-W126 HydrophobicContact CG1-CE3 4.23Å; V123-W126 HydrophobicContact CG1-CH2 4.17Å; V123-W126 HydrophobicContact CG1-CZ2 4.03Å; V123-W126 HydrophobicContact CG1-CZ3 4.26Å; V123-W126 VanDerWaalsContact O-CB 3.28Å; V123-W126 WeakPolarHBondContact O-CB 3.41Å; V123-W126 PolarHBondContact O-N 3Å; W126-V128 HydrophobicContact CB-CG1 4.42Å; W126-V128 PolarHBondContact O-N 3.32Å; W126-V128 VanDerWaalsContact O-N 3.07Å; W126-F129 HydrophobicContact CB-CD2 4.39Å; W126-F129 PolarHBondContact O-N 2.92Å; W126-Q130 PolarHBondContact O-N 2.92Å; W126-Q130 VanDerWaalsContact O-N 3.11Å; W126-W275 HydrophobicContact CB-CE3 4.16Å; W126-W275 HydrophobicContact CB-CZ3 4.31Å; W126-W275 HydrophobicContact CE3-CB 3.72Å; W126-W275 HydrophobicContact CE3-CD2 4.07Å; W126-W275 HydrophobicContact CE3-CE3 4.21Å; W126-W275 AromaticContact CE3-CG 3.87Å; W126-W275 HydrophobicContact CE3-CG 3.87Å; W126-W275 HydrophobicContact CZ3-CB 3.7Å; W126-W275 AromaticContact CZ3-CG 3.9Å; W126-W275 HydrophobicContact CZ3-CG 3.9Å
127	E	93.8	Very high	94.4	Very high	72 Å²	72	34.3 Å²	34.3	34%	0.336	16%	0.162	S	C	.	.	H	α-helix	trans	-53.9	-36.4	-175.4	-160.9	-166.1	148.5	0	0	113	Q130 K131 W275 Y278	E127-Q130 PolarHBondContact O-N 2.87Å; E127-K131 HydrophobicContact CG-CD 3.89Å; E127-K131 HydrophobicContact CG-CG 4.42Å; E127-K131 WeakPolarHBondContact O-CB 3.29Å; E127-K131 WeakPolarHBondContact O-CG 3.26Å; E127-K131 PolarHBondContact O-N 3.09Å; E127-K131 WeakPolarHBondContact OE1-CE 3.35Å; E127-K131 IonicContact OE1-NZ 3.6Å; E127-K131 PolarHBondContact OE1-NZ 3.5Å; E127-W275 HydrophobicContact CB-CH2 4.38Å; E127-W275 HydrophobicContact CB-CZ3 3.73Å; E127-Y278 HydrophobicContact CB-CE1 4.36Å; E127-Y278 HydrophobicContact CG-CE1 4.14Å; E127-Y278 WeakPolarHBondContact OE1-CE1 3.29Å; E127-Y278 PolarHBondContact OE1-OH 2.99Å
128	V	94.4	Very high	94.4	Very high	0 Å²	0	34.3 Å²	34.3	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-66.2	-40.5	179.1	67.5	0	0	0	0	112.3	W126 V132 L216 W275 Y278	W126-V128 HydrophobicContact CB-CG1 4.42Å; W126-V128 PolarHBondContact O-N 3.32Å; W126-V128 VanDerWaalsContact O-N 3.07Å; V128-V132 WeakPolarHBondContact O-CA 3.35Å; V128-V132 VanDerWaalsContact O-CB 3.28Å; V128-V132 WeakPolarHBondContact O-CB 3.24Å; V128-V132 PolarHBondContact O-N 3.15Å; V128-L216 HydrophobicContact CG2-CD2 4.08Å; V128-W275 HydrophobicContact CB-CE3 4.36Å; V128-W275 HydrophobicContact CG1-CB 4.27Å; V128-W275 HydrophobicContact CG1-CE3 4.07Å; V128-Y278 HydrophobicContact CB-CD1 4.24Å; V128-Y278 HydrophobicContact CB-CD2 4.49Å; V128-Y278 HydrophobicContact CB-CG 4Å; V128-Y278 HydrophobicContact CG2-CD2 4.13Å; V128-Y278 HydrophobicContact CG2-CG 3.93Å
129	F	94.3	Very high	94.4	Very high	0 Å²	0	33.4 Å²	33.4	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-73.2	-33	178.4	-81.1	-96.3	0	0	0	111.8	L120 V123 W126 T133 V135 F136 V139	L120-F129 HydrophobicContact CD1-CE1 4.47Å; V123-F129 HydrophobicContact CB-CD2 4.14Å; V123-F129 HydrophobicContact CB-CE2 3.79Å; V123-F129 HydrophobicContact CB-CZ 4.21Å; V123-F129 HydrophobicContact CG2-CD2 4.27Å; V123-F129 HydrophobicContact CG2-CE1 4.09Å; V123-F129 HydrophobicContact CG2-CE2 3.75Å; V123-F129 HydrophobicContact CG2-CZ 3.64Å; V123-F129 WeakPolarHBondContact O-CB 3.45Å; V123-F129 WeakPolarHBondContact O-CD2 3.39Å; V123-F129 WeakPolarHBondContact O-CG 3.16Å; W126-F129 HydrophobicContact CB-CD2 4.39Å; W126-F129 PolarHBondContact O-N 2.92Å; F129-T133 WeakPolarHBondContact O-CA 3.02Å; F129-V135 HydrophobicContact CD1-CB 4.18Å; F129-V135 HydrophobicContact CD1-CG1 3.89Å; F129-V135 HydrophobicContact CE1-CB 4.16Å; F129-V135 HydrophobicContact CE1-CG1 3.39Å; F129-V135 HydrophobicContact CE2-CG1 4.25Å; F129-V135 HydrophobicContact CZ-CG1 3.59Å; F129-F136 HydrophobicContact CB-CE2 4.17Å; F129-F136 HydrophobicContact CB-CZ 3.85Å; F129-F136 AromaticContact CD1-CD1 3.89Å; F129-F136 HydrophobicContact CD1-CD1 3.89Å; F129-F136 AromaticContact CD1-CE1 3.5Å; F129-F136 HydrophobicContact CD1-CE1 3.5Å; F129-F136 VanDerWaalsContact CD1-CE1 3.5Å; F129-F136 HydrophobicContact CD1-CE2 4.21Å; F129-F136 HydrophobicContact CD1-CG 4.4Å; F129-F136 AromaticContact CD1-CZ 3.68Å; F129-F136 HydrophobicContact CD1-CZ 3.68Å; F129-F136 HydrophobicContact CE1-CD1 4.28Å; F129-F136 HydrophobicContact CE1-CE1 4.15Å; F129-F136 HydrophobicContact CG-CE1 4.41Å; F129-F136 HydrophobicContact CG-CZ 4.22Å; F129-F136 WeakPolarHBondContact O-CE2 3.44Å; F129-V139 HydrophobicContact CE1-CG2 4.45Å
130	Q	93.1	Very high	94.4	Very high	117 Å²	117	32 Å²	32	55%	0.547	15%	0.149	S	C	.	.	H	α-helix	trans	-74.1	-36.3	177	-67.3	-178.4	-19.9	0	0	113.1	W126 E127	W126-Q130 PolarHBondContact O-N 2.92Å; W126-Q130 VanDerWaalsContact O-N 3.11Å; E127-Q130 PolarHBondContact O-N 2.87Å
131	K	92.1	Very high	94.3	Very high	117 Å²	117	32 Å²	32	51%	0.509	15%	0.149	S	C	.	.	H	α-helix	trans	-91.9	-25.8	-178.1	-71	-176.7	176.2	179.9	0	114.1	E127 H213 Y278	E127-K131 HydrophobicContact CG-CD 3.89Å; E127-K131 HydrophobicContact CG-CG 4.42Å; E127-K131 WeakPolarHBondContact O-CB 3.29Å; E127-K131 WeakPolarHBondContact O-CG 3.26Å; E127-K131 PolarHBondContact O-N 3.09Å; E127-K131 WeakPolarHBondContact OE1-CE 3.35Å; E127-K131 IonicContact OE1-NZ 3.6Å; E127-K131 PolarHBondContact OE1-NZ 3.5Å; K131-H213 PolarHBondContact O-CE1 2.85Å; K131-H213 VanDerWaalsContact O-CE1 3.26Å; K131-Y278 WeakPolarHBondContact CD-OH 3.1Å; K131-Y278 PolarHBondContact NZ-OH 3.02Å
132	V	93.6	Very high	94.3	Very high	0 Å²	0	31.7 Å²	31.7	0%	0	15%	0.148	C	C	.	.			trans	-124.2	71.5	179.9	-168.3	0	0	0	0	107.3	V128 E134 V135 H213 L216 L217	V128-V132 WeakPolarHBondContact O-CA 3.35Å; V128-V132 VanDerWaalsContact O-CB 3.28Å; V128-V132 WeakPolarHBondContact O-CB 3.24Å; V128-V132 PolarHBondContact O-N 3.15Å; V132-E134 VanDerWaalsContact C-OE2 3.31Å; V132-E134 WeakPolarHBondContact CA-OE2 3.29Å; V132-E134 VanDerWaalsContact CG1-OE2 3.28Å; V132-E134 WeakPolarHBondContact CG1-OE2 3.32Å; V132-E134 PolarHBondContact O-N 2.9Å; V132-E134 VanDerWaalsContact O-N 3.14Å; V132-V135 HydrophobicContact CB-CG2 4.27Å; V132-V135 HydrophobicContact CG1-CG2 4.1Å; V132-V135 WeakPolarHBondContact O-CB 3.31Å; V132-V135 VanDerWaalsContact O-CG2 3.28Å; V132-V135 WeakPolarHBondContact O-CG2 3.2Å; V132-V135 PolarHBondContact O-N 3.35Å; V132-V135 VanDerWaalsContact O-N 3.09Å; V132-H213 HydrophobicContact CG1-CB 4.02Å; V132-L216 HydrophobicContact CG1-CD2 4.43Å; V132-L216 HydrophobicContact CG2-CD2 4.01Å; V132-L217 HydrophobicContact CG1-CD2 4.19Å; V132-L217 HydrophobicContact CG1-CG 4.31Å
133	T	93.6	Very high	94.3	Very high	34 Å²	34	27.8 Å²	27.8	21%	0.209	13%	0.128	C	C	.	.	T	Hydrogen-bonded Turn	trans	-65.6	-18.4	-173.5	73.6	0	0	0	0	111.7	F129 V135 F136 D338	F129-T133 WeakPolarHBondContact O-CA 3.02Å; T133-V135 PolarHBondContact O-N 2.91Å; T133-F136 WeakPolarHBondContact O-CB 3.17Å; T133-F136 WeakPolarHBondContact O-CD2 3.28Å; T133-F136 PolarHBondContact O-N 3.41Å; T133-D338 WeakPolarHBondContact CB-OD1 3.34Å; T133-D338 PolarHBondContact OG1-OD1 2.92Å
134	E	94.5	Very high	94	Very high	27 Å²	27	27.8 Å²	27.8	13%	0.126	13%	0.128	C	C	.	.	H	α-helix	trans	-59.1	-16.6	172.7	-54.6	94.7	149.4	0	0	113.3	V132 F136 I137 L138 H213 L217	V132-E134 VanDerWaalsContact C-OE2 3.31Å; V132-E134 WeakPolarHBondContact CA-OE2 3.29Å; V132-E134 VanDerWaalsContact CG1-OE2 3.28Å; V132-E134 WeakPolarHBondContact CG1-OE2 3.32Å; V132-E134 PolarHBondContact O-N 2.9Å; V132-E134 VanDerWaalsContact O-N 3.14Å; E134-F136 VanDerWaalsContact C-N 3.27Å; E134-F136 PolarHBondContact O-N 2.94Å; E134-I137 HydrophobicContact CB-CD1 4.5Å; E134-I137 WeakPolarHBondContact O-CB 3.47Å; E134-I137 PolarHBondContact O-N 2.96Å; E134-L138 PolarHBondContact O-N 3.48Å; E134-H213 IonicContact OE1-ND1 3.63Å; E134-H213 IonicContact OE2-ND1 3.57Å; E134-L217 HydrophobicContact CB-CD1 3.56Å; E134-L217 HydrophobicContact CB-CD2 4.02Å; E134-L217 HydrophobicContact CB-CG 4.41Å; E134-L217 HydrophobicContact CG-CD1 4.25Å
135	V	96.1	Very high	93.6	Very high	0 Å²	0	27.5 Å²	27.5	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-62.5	-34	170	-178.8	0	0	0	0	111.1	F129 V132 T133 I137 L138 V139 L217 L270	F129-V135 HydrophobicContact CD1-CB 4.18Å; F129-V135 HydrophobicContact CD1-CG1 3.89Å; F129-V135 HydrophobicContact CE1-CB 4.16Å; F129-V135 HydrophobicContact CE1-CG1 3.39Å; F129-V135 HydrophobicContact CE2-CG1 4.25Å; F129-V135 HydrophobicContact CZ-CG1 3.59Å; V132-V135 HydrophobicContact CB-CG2 4.27Å; V132-V135 HydrophobicContact CG1-CG2 4.1Å; V132-V135 WeakPolarHBondContact O-CB 3.31Å; V132-V135 VanDerWaalsContact O-CG2 3.28Å; V132-V135 WeakPolarHBondContact O-CG2 3.2Å; V132-V135 PolarHBondContact O-N 3.35Å; V132-V135 VanDerWaalsContact O-N 3.09Å; T133-V135 PolarHBondContact O-N 2.91Å; V135-I137 VanDerWaalsContact C-N 3.29Å; V135-I137 PolarHBondContact O-N 2.67Å; V135-L138 WeakPolarHBondContact O-CB 3.45Å; V135-L138 PolarHBondContact O-N 3.23Å; V135-L138 VanDerWaalsContact O-N 3.13Å; V135-V139 PolarHBondContact O-N 2.93Å; V135-L217 HydrophobicContact CB-CD2 4.48Å; V135-L217 HydrophobicContact CG2-CD2 3.75Å; V135-L270 HydrophobicContact CG1-CD2 4.23Å; V135-L270 HydrophobicContact CG1-CG 4.31Å
136	F	95.6	Very high	93.2	Very high	5 Å²	5	23.9 Å²	23.9	2%	0.022	11%	0.111	C	C	.	.	H	α-helix	trans	-64.6	-34.2	173.8	-66.5	-64.8	0	0	0	112.2	L120 Q124 F129 T133 E134 L138 V139 P140 D338 V341	L120-F136 HydrophobicContact CD1-CD1 4.39Å; L120-F136 HydrophobicContact CD1-CE1 4.29Å; Q124-F136 HydrophobicContact CB-CE1 3.86Å; Q124-F136 HydrophobicContact CB-CZ 3.74Å; F129-F136 HydrophobicContact CB-CE2 4.17Å; F129-F136 HydrophobicContact CB-CZ 3.85Å; F129-F136 AromaticContact CD1-CD1 3.89Å; F129-F136 HydrophobicContact CD1-CD1 3.89Å; F129-F136 AromaticContact CD1-CE1 3.5Å; F129-F136 HydrophobicContact CD1-CE1 3.5Å; F129-F136 VanDerWaalsContact CD1-CE1 3.5Å; F129-F136 HydrophobicContact CD1-CE2 4.21Å; F129-F136 HydrophobicContact CD1-CG 4.4Å; F129-F136 AromaticContact CD1-CZ 3.68Å; F129-F136 HydrophobicContact CD1-CZ 3.68Å; F129-F136 HydrophobicContact CE1-CD1 4.28Å; F129-F136 HydrophobicContact CE1-CE1 4.15Å; F129-F136 HydrophobicContact CG-CE1 4.41Å; F129-F136 HydrophobicContact CG-CZ 4.22Å; F129-F136 WeakPolarHBondContact O-CE2 3.44Å; T133-F136 WeakPolarHBondContact O-CB 3.17Å; T133-F136 WeakPolarHBondContact O-CD2 3.28Å; T133-F136 PolarHBondContact O-N 3.41Å; E134-F136 VanDerWaalsContact C-N 3.27Å; E134-F136 PolarHBondContact O-N 2.94Å; F136-L138 PolarHBondContact O-N 2.84Å; F136-V139 PolarHBondContact O-N 3.45Å; F136-P140 WeakPolarHBondContact O-CD 3.34Å; F136-D338 HydrophobicContact CB-CB 3.92Å; F136-V341 HydrophobicContact CD1-CG1 4.28Å; F136-V341 HydrophobicContact CE1-CB 4.38Å; F136-V341 HydrophobicContact CE1-CG1 3.64Å; F136-V341 HydrophobicContact CE2-CG1 4.06Å; F136-V341 HydrophobicContact CZ-CB 4.43Å; F136-V341 HydrophobicContact CZ-CG1 3.51Å
137	I	95.2	Very high	92.2	Very high	0 Å²	0	20.1 Å²	20.1	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-63.6	-34.6	174.8	-52	179.3	0	0	0	110.9	E134 V135 A198 F201 G334 L335 D338	E134-I137 HydrophobicContact CB-CD1 4.5Å; E134-I137 WeakPolarHBondContact O-CB 3.47Å; E134-I137 PolarHBondContact O-N 2.96Å; V135-I137 VanDerWaalsContact C-N 3.29Å; V135-I137 PolarHBondContact O-N 2.67Å; I137-A198 HydrophobicContact CB-CB 4.15Å; I137-A198 HydrophobicContact CG2-CB 4.15Å; I137-F201 HydrophobicContact CD1-CB 4.18Å; I137-F201 HydrophobicContact CG2-CB 4.19Å; I137-F201 HydrophobicContact CG2-CD2 4.28Å; I137-G334 WeakPolarHBondContact CA-O 3.4Å; I137-L335 HydrophobicContact CD1-CD1 3.93Å; I137-D338 HydrophobicContact CD1-CB 4.37Å; I137-D338 HydrophobicContact CG1-CB 3.63Å
138	L	95.5	Very high	91.6	Very high	0 Å²	0	16.9 Å²	16.9	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-75	-25.8	-179.7	-173	61.3	0	0	0	113.1	E134 V135 F136 A141 L142 A194 A198 S221 L270	E134-L138 PolarHBondContact O-N 3.48Å; V135-L138 WeakPolarHBondContact O-CB 3.45Å; V135-L138 PolarHBondContact O-N 3.23Å; V135-L138 VanDerWaalsContact O-N 3.13Å; F136-L138 PolarHBondContact O-N 2.84Å; L138-A141 PolarHBondContact O-N 3.14Å; L138-L142 HydrophobicContact CD1-CD1 4.05Å; L138-L142 HydrophobicContact CD1-CD2 4.26Å; L138-L142 HydrophobicContact CD1-CG 3.81Å; L138-L142 HydrophobicContact CD2-CD1 3.97Å; L138-L142 HydrophobicContact CG-CD1 3.67Å; L138-L142 HydrophobicContact CG-CG 3.86Å; L138-L142 PolarHBondContact O-N 3.05Å; L138-A194 HydrophobicContact CD1-CB 3.72Å; L138-A198 HydrophobicContact CB-CB 4.44Å; L138-S221 WeakPolarHBondContact CD1-OG 3.24Å; L138-L270 HydrophobicContact CD2-CD1 3.71Å; L138-L270 HydrophobicContact CG-CD1 4.43Å
139	V	95.9	Very high	91.1	Very high	2 Å²	2	17.1 Å²	17.1	1%	0.012	8%	0.084	C	C	.	.	H	α-helix	trans	-56.7	-62.6	-176.5	167	0	0	0	0	111.4	L120 F129 V135 F136 A141 L142 L143 L267 L270 L337	L120-V139 HydrophobicContact CD1-CG2 4.22Å; L120-V139 HydrophobicContact CD2-CG1 4.22Å; F129-V139 HydrophobicContact CE1-CG2 4.45Å; V135-V139 PolarHBondContact O-N 2.93Å; F136-V139 PolarHBondContact O-N 3.45Å; V139-A141 VanDerWaalsContact C-N 3.27Å; V139-A141 PolarHBondContact O-N 3.25Å; V139-L142 PolarHBondContact O-N 3.49Å; V139-L143 HydrophobicContact CG1-CD1 3.84Å; V139-L143 HydrophobicContact CG1-CG 4.31Å; V139-L143 VanDerWaalsContact O-CG 3.29Å; V139-L143 WeakPolarHBondContact O-CG 3.49Å; V139-L143 PolarHBondContact O-N 2.91Å; V139-L267 HydrophobicContact CG1-CD1 4.01Å; V139-L267 HydrophobicContact CG2-CD1 3.75Å; V139-L270 HydrophobicContact CG2-CD2 3.67Å; V139-L337 HydrophobicContact CB-CD2 4.26Å; V139-L337 HydrophobicContact CG1-CD2 4.2Å
140	P	94	Very high	90.6	Very high	2 Å²	2	17.2 Å²	17.2	1%	0.013	8%	0.084	C	C	.	.	H	α-helix	trans	-62.3	-33.4	-179.4	-27.5	39.8	0	0	0	113.3	F136 L142 L143 G144 L337	F136-P140 WeakPolarHBondContact O-CD 3.34Å; P140-L142 PolarHBondContact O-N 3.13Å; P140-L143 PolarHBondContact O-N 3.39Å; P140-G144 PolarHBondContact O-N 3.4Å; P140-L337 HydrophobicContact CG-CD2 3.92Å
141	A	94.5	Very high	89.8	Confident	0 Å²	0	12.2 Å²	12.2	0%	0	6%	0.061	C	C	.	.	H	α-helix	trans	-62.3	-42.2	178.2	0	0	0	0	0	112.6	L138 V139 L145 A194 M327 S331	L138-A141 PolarHBondContact O-N 3.14Å; V139-A141 VanDerWaalsContact C-N 3.27Å; V139-A141 PolarHBondContact O-N 3.25Å; A141-L145 VanDerWaalsContact O-CB 3.32Å; A141-L145 WeakPolarHBondContact O-CB 3.42Å; A141-L145 PolarHBondContact O-N 3.47Å; A141-A194 HydrophobicContact CB-CB 4.16Å; A141-M327 HydrophobicContact CB-CG 4.41Å; A141-S331 WeakPolarHBondContact CB-OG 3.37Å
142	L	94.5	Very high	89.2	Confident	3 Å²	3	7.8 Å²	7.8	2%	0.016	4%	0.044	C	C	.	.	H	α-helix	trans	-76.9	-36.5	177.8	-69.2	-176.6	0	0	0	112.9	L138 V139 P140 L145 K146 T224 A225 T266 L270	L138-L142 HydrophobicContact CD1-CD1 4.05Å; L138-L142 HydrophobicContact CD1-CD2 4.26Å; L138-L142 HydrophobicContact CD1-CG 3.81Å; L138-L142 HydrophobicContact CD2-CD1 3.97Å; L138-L142 HydrophobicContact CG-CD1 3.67Å; L138-L142 HydrophobicContact CG-CG 3.86Å; L138-L142 PolarHBondContact O-N 3.05Å; V139-L142 PolarHBondContact O-N 3.49Å; P140-L142 PolarHBondContact O-N 3.13Å; L142-L145 HydrophobicContact CD2-CD2 4.3Å; L142-L145 WeakPolarHBondContact O-CB 3.44Å; L142-L145 PolarHBondContact O-N 3.21Å; L142-K146 PolarHBondContact O-N 3.41Å; L142-T224 HydrophobicContact CD1-CG2 4.02Å; L142-A225 HydrophobicContact CD2-CB 4.09Å; L142-T266 HydrophobicContact CB-CG2 3.87Å; L142-L270 HydrophobicContact CD1-CD1 3.88Å; L142-L270 HydrophobicContact CD1-CD2 4.18Å; L142-L270 HydrophobicContact CD1-CG 4.46Å
143	L	92.9	Very high	88.6	Confident	17 Å²	17	8 Å²	8	9%	0.089	5%	0.045	C	C	.	.	H	α-helix	trans	-64.5	-46.1	174.5	-63	-175.2	0	0	0	110.9	V139 P140 L145 K146 G147 D263 T266 L267	V139-L143 HydrophobicContact CG1-CD1 3.84Å; V139-L143 HydrophobicContact CG1-CG 4.31Å; V139-L143 VanDerWaalsContact O-CG 3.29Å; V139-L143 WeakPolarHBondContact O-CG 3.49Å; V139-L143 PolarHBondContact O-N 2.91Å; P140-L143 PolarHBondContact O-N 3.39Å; L143-L145 PolarHBondContact O-N 2.79Å; L143-K146 WeakPolarHBondContact O-CB 3.47Å; L143-K146 VanDerWaalsContact O-CG 3.3Å; L143-K146 WeakPolarHBondContact O-CG 3.1Å; L143-K146 PolarHBondContact O-N 3.47Å; L143-G147 PolarHBondContact O-N 2.88Å; L143-D263 HydrophobicContact CD2-CB 4.08Å; L143-T266 HydrophobicContact CD2-CG2 4.12Å; L143-L267 HydrophobicContact CD2-CB 4.4Å
144	G	88.5	Confident	88	Confident	4 Å²	4	6.3 Å²	6.3	4%	0.041	4%	0.035	C	C	.	.	H	α-helix	trans	-62.2	-39.4	174.2	0	0	0	0	0	112.9	P140 K146 G147 N148	P140-G144 PolarHBondContact O-N 3.4Å; G144-K146 VanDerWaalsContact C-N 3.31Å; G144-K146 PolarHBondContact O-N 2.87Å; G144-G147 PolarHBondContact O-N 3.33Å; G144-N148 VanDerWaalsContact O-CG 3.25Å; G144-N148 PolarHBondContact O-N 3.44Å; G144-N148 VanDerWaalsContact O-N 3.17Å; G144-N148 PolarHBondContact O-ND2 3.03Å; G144-N148 PolarHBondContact O-OD1 2.82Å
145	L	86.4	Confident	87	Confident	5 Å²	5	6.9 Å²	6.9	3%	0.026	4%	0.041	C	C	.	.	H	α-helix	trans	-56.9	-43.6	175.1	179	59.3	0	0	0	112	A141 L142 L143 G147 N148 L149 V190 A225 V323	A141-L145 VanDerWaalsContact O-CB 3.32Å; A141-L145 WeakPolarHBondContact O-CB 3.42Å; A141-L145 PolarHBondContact O-N 3.47Å; L142-L145 HydrophobicContact CD2-CD2 4.3Å; L142-L145 WeakPolarHBondContact O-CB 3.44Å; L142-L145 PolarHBondContact O-N 3.21Å; L143-L145 PolarHBondContact O-N 2.79Å; L145-G147 PolarHBondContact O-N 3.5Å; L145-N148 PolarHBondContact O-N 2.92Å; L145-L149 HydrophobicContact CD1-CD1 3.7Å; L145-L149 HydrophobicContact CD1-CD2 4.3Å; L145-L149 HydrophobicContact CD1-CG 3.79Å; L145-L149 HydrophobicContact CG-CD1 3.93Å; L145-L149 HydrophobicContact CG-CG 4.26Å; L145-L149 WeakPolarHBondContact O-CG 2.98Å; L145-L149 PolarHBondContact O-N 3.19Å; L145-V190 HydrophobicContact CD1-CB 3.73Å; L145-V190 HydrophobicContact CD1-CG1 3.5Å; L145-V190 VanDerWaalsContact CD1-CG1 3.5Å; L145-V190 HydrophobicContact CD1-CG2 4.22Å; L145-V190 HydrophobicContact CD2-CB 3.98Å; L145-V190 HydrophobicContact CD2-CG1 3.96Å; L145-V190 HydrophobicContact CG-CG1 4.27Å; L145-A225 HydrophobicContact CD2-CB 4.2Å; L145-V323 HydrophobicContact CD1-CG1 3.84Å
146	K	84.2	Confident	86.1	Confident	13 Å²	13	9.8 Å²	9.8	6%	0.057	5%	0.052	C	C	.	.	H	α-helix	trans	-59.2	-42	176.9	109.9	-176.1	172	66.1	0	110.8	L142 L143 G144 N148 L149 E150 A258 A259 G262 D263	L142-K146 PolarHBondContact O-N 3.41Å; L143-K146 WeakPolarHBondContact O-CB 3.47Å; L143-K146 VanDerWaalsContact O-CG 3.3Å; L143-K146 WeakPolarHBondContact O-CG 3.1Å; L143-K146 PolarHBondContact O-N 3.47Å; G144-K146 VanDerWaalsContact C-N 3.31Å; G144-K146 PolarHBondContact O-N 2.87Å; K146-N148 PolarHBondContact O-N 3.11Å; K146-L149 PolarHBondContact O-N 3.35Å; K146-E150 HydrophobicContact CB-CG 4.45Å; K146-E150 VanDerWaalsContact O-CB 3.28Å; K146-E150 WeakPolarHBondContact O-CB 3.3Å; K146-E150 WeakPolarHBondContact O-CG 3.49Å; K146-E150 PolarHBondContact O-N 2.92Å; K146-A258 PolarHBondContact NZ-O 2.83Å; K146-A259 VanDerWaalsContact NZ-CA 3.26Å; K146-A259 PolarHBondContact NZ-O 3.23Å; K146-G262 WeakPolarHBondContact CD-O 3.25Å; K146-G262 VanDerWaalsContact CE-CA 3.49Å; K146-D263 WeakPolarHBondContact CD-OD1 3.19Å; K146-D263 WeakPolarHBondContact CE-OD1 3.42Å; K146-D263 IonicContact NZ-OD1 2.6Å
147	G	72.7	Confident	85.4	Confident	5 Å²	5	9.6 Å²	9.6	5%	0.052	5%	0.052	C	C	.	.	H	α-helix	trans	-60.5	-39.6	-176.2	0	0	0	0	0	109	L143 G144 L145 M151	L143-G147 PolarHBondContact O-N 2.88Å; G144-G147 PolarHBondContact O-N 3.33Å; L145-G147 PolarHBondContact O-N 3.5Å; G147-M151 WeakPolarHBondContact O-CB 3.29Å; G147-M151 WeakPolarHBondContact O-CE 3.47Å; G147-M151 WeakPolarHBondContact O-CG 3.5Å; G147-M151 PolarHBondContact O-N 2.98Å
148	N	81	Confident	84.5	Confident	3 Å²	3	9.6 Å²	9.6	2%	0.016	5%	0.052	C	C	.	.	H	α-helix	trans	-74.5	-42.1	-178.1	-57.8	-9.1	0	0	0	111.9	G144 L145 K146 T152 A326 P480 T483	G144-N148 VanDerWaalsContact O-CG 3.25Å; G144-N148 PolarHBondContact O-N 3.44Å; G144-N148 VanDerWaalsContact O-N 3.17Å; G144-N148 PolarHBondContact O-ND2 3.03Å; G144-N148 PolarHBondContact O-OD1 2.82Å; L145-N148 PolarHBondContact O-N 2.92Å; K146-N148 PolarHBondContact O-N 3.11Å; N148-T152 WeakPolarHBondContact O-CB 3.28Å; N148-T152 PolarHBondContact O-OG1 3.06Å; N148-A326 WeakPolarHBondContact ND2-CB 3.42Å; N148-P480 HydrophobicContact CB-CB 4.34Å; N148-P480 HydrophobicContact CB-CG 4.17Å; N148-P480 VanDerWaalsContact OD1-CA 3.28Å; N148-P480 WeakPolarHBondContact OD1-CA 3.18Å; N148-T483 PolarHBondContact OD1-OG1 3.48Å
149	L	84.1	Confident	83.4	Confident	5 Å²	5	12.7 Å²	12.7	3%	0.026	7%	0.071	C	C	.	.	H	α-helix	trans	-82	-50.4	-176.3	-58.8	-173.3	0	0	0	112.5	L145 K146 T152 L153 I183 Q186 A187 V323	L145-L149 HydrophobicContact CD1-CD1 3.7Å; L145-L149 HydrophobicContact CD1-CD2 4.3Å; L145-L149 HydrophobicContact CD1-CG 3.79Å; L145-L149 HydrophobicContact CG-CD1 3.93Å; L145-L149 HydrophobicContact CG-CG 4.26Å; L145-L149 WeakPolarHBondContact O-CG 2.98Å; L145-L149 PolarHBondContact O-N 3.19Å; K146-L149 PolarHBondContact O-N 3.35Å; L149-T152 PolarHBondContact O-N 3.1Å; L149-L153 WeakPolarHBondContact O-CB 3.16Å; L149-L153 PolarHBondContact O-N 3.26Å; L149-I183 HydrophobicContact CB-CG2 4.37Å; L149-I183 HydrophobicContact CD1-CG2 4.31Å; L149-Q186 HydrophobicContact CD1-CB 4Å; L149-Q186 HydrophobicContact CD2-CB 3.64Å; L149-Q186 HydrophobicContact CD2-CG 4.29Å; L149-A187 HydrophobicContact CD1-CB 3.91Å; L149-V323 HydrophobicContact CD2-CG1 4.39Å
150	E	84.4	Confident	82.4	Confident	3 Å²	3	13 Å²	13	1%	0.014	7%	0.074	C	C	.	.	H	α-helix	trans	-77.6	-37.4	-172.1	-55.5	-54.8	150.6	0	0	112.3	K146 T152 L153 A154 S229 L232 G233 A258	K146-E150 HydrophobicContact CB-CG 4.45Å; K146-E150 VanDerWaalsContact O-CB 3.28Å; K146-E150 WeakPolarHBondContact O-CB 3.3Å; K146-E150 WeakPolarHBondContact O-CG 3.49Å; K146-E150 PolarHBondContact O-N 2.92Å; E150-T152 VanDerWaalsContact C-N 3.32Å; E150-L153 WeakPolarHBondContact O-CB 3.28Å; E150-L153 PolarHBondContact O-N 2.87Å; E150-A154 WeakPolarHBondContact O-CB 3.4Å; E150-A154 PolarHBondContact O-N 3.22Å; E150-S229 VanDerWaalsContact OE1-CA 3.29Å; E150-S229 WeakPolarHBondContact OE1-CA 3.45Å; E150-S229 WeakPolarHBondContact OE1-CB 3.5Å; E150-L232 HydrophobicContact CG-CB 4.09Å; E150-L232 HydrophobicContact CG-CD1 4.26Å; E150-G233 PolarHBondContact OE2-N 3.37Å; E150-A258 HydrophobicContact CB-CB 4.44Å
151	M	77.4	Confident	81.5	Confident	12 Å²	12	13.1 Å²	13.1	6%	0.059	7%	0.074	C	C	.	.	H	α-helix	trans	-69.1	-35.6	174.3	-57	-167.9	-101.1	0	0	110.9	G147 A154 S155 T255 A365 I479 T483	G147-M151 WeakPolarHBondContact O-CB 3.29Å; G147-M151 WeakPolarHBondContact O-CE 3.47Å; G147-M151 WeakPolarHBondContact O-CG 3.5Å; G147-M151 PolarHBondContact O-N 2.98Å; M151-A154 PolarHBondContact O-N 3.03Å; M151-S155 WeakPolarHBondContact O-CB 3.37Å; M151-S155 PolarHBondContact O-N 3.14Å; M151-T255 HydrophobicContact SD-CG2 4.34Å; M151-A365 HydrophobicContact CE-CB 4.44Å; M151-A365 HydrophobicContact SD-CB 4.14Å; M151-I479 HydrophobicContact CE-CG2 4.45Å; M151-T483 HydrophobicContact CE-CG2 3.86Å
152	T	78.2	Confident	80.5	Confident	24 Å²	24	16.9 Å²	16.9	15%	0.147	10%	0.095	C	C	.	.	H	α-helix	trans	-66.6	-40.6	173.3	-60.2	0	0	0	0	111.5	N148 L149 E150 R156	N148-T152 WeakPolarHBondContact O-CB 3.28Å; N148-T152 PolarHBondContact O-OG1 3.06Å; L149-T152 PolarHBondContact O-N 3.1Å; E150-T152 VanDerWaalsContact C-N 3.32Å; T152-R156 HydrophobicContact CG2-CG 4.46Å; T152-R156 VanDerWaalsContact CG2-CZ 3.43Å; T152-R156 WeakPolarHBondContact O-CB 3.45Å; T152-R156 VanDerWaalsContact O-CG 3.29Å; T152-R156 WeakPolarHBondContact O-CG 3.4Å; T152-R156 PolarHBondContact O-N 3.29Å
153	L	82	Confident	79.5	Confident	3 Å²	3	21.3 Å²	21.3	2%	0.016	12%	0.117	C	C	.	.	H	α-helix	trans	-57.4	-52.1	172.2	178.2	61.7	0	0	0	111.1	L149 E150 S155 R156 L157 N179 I183 M236	L149-L153 WeakPolarHBondContact O-CB 3.16Å; L149-L153 PolarHBondContact O-N 3.26Å; E150-L153 WeakPolarHBondContact O-CB 3.28Å; E150-L153 PolarHBondContact O-N 2.87Å; L153-S155 PolarHBondContact O-N 2.92Å; L153-R156 PolarHBondContact O-N 3.23Å; L153-L157 HydrophobicContact CD1-CD1 3.53Å; L153-L157 HydrophobicContact CD1-CG 3.81Å; L153-L157 HydrophobicContact CG-CD1 3.97Å; L153-L157 HydrophobicContact CG-CG 4.43Å; L153-L157 WeakPolarHBondContact O-CB 3.37Å; L153-L157 PolarHBondContact O-N 3.49Å; L153-N179 HydrophobicContact CD1-CB 3.51Å; L153-I183 HydrophobicContact CB-CD1 3.56Å; L153-I183 HydrophobicContact CD1-CD1 3.7Å; L153-I183 HydrophobicContact CD2-CD1 3.52Å; L153-I183 HydrophobicContact CG-CD1 3.74Å; L153-M236 HydrophobicContact CD2-CB 4.21Å
154	A	80.6	Confident	78.4	Confident	0 Å²	0	21.3 Å²	21.3	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-58.8	-49.7	-177.3	0	0	0	0	0	110.1	E150 M151 R156 L157 S158 M236 A254	E150-A154 WeakPolarHBondContact O-CB 3.4Å; E150-A154 PolarHBondContact O-N 3.22Å; M151-A154 PolarHBondContact O-N 3.03Å; A154-R156 PolarHBondContact O-N 3.44Å; A154-L157 PolarHBondContact O-N 3.08Å; A154-S158 WeakPolarHBondContact O-CB 3.34Å; A154-S158 PolarHBondContact O-N 2.67Å; A154-S158 PolarHBondContact O-OG 3.28Å; A154-M236 HydrophobicContact CB-CE 4.3Å; A154-A254 HydrophobicContact CB-CB 4.15Å
155	S	74.4	Confident	77.4	Confident	38 Å²	38	26.4 Å²	26.4	27%	0.266	14%	0.144	S	C	.	.	H	α-helix	trans	-56.9	-48.9	176.7	174.4	0	0	0	0	112.5	M151 L153 T159	M151-S155 WeakPolarHBondContact O-CB 3.37Å; M151-S155 PolarHBondContact O-N 3.14Å; L153-S155 PolarHBondContact O-N 2.92Å; S155-T159 VanDerWaalsContact O-CB 3.28Å; S155-T159 WeakPolarHBondContact O-CB 3.46Å; S155-T159 PolarHBondContact O-N 3.06Å; S155-T159 PolarHBondContact O-OG1 3.45Å
156	R	76.5	Confident	76.4	Confident	61 Å²	61	26.6 Å²	26.6	23%	0.23	15%	0.145	C	C	.	.	H	α-helix	trans	-64.1	-45.5	-179.1	-74.7	177.5	-179.9	161.1	6	112.9	T152 L153 A154 A160 V315 N476	T152-R156 HydrophobicContact CG2-CG 4.46Å; T152-R156 VanDerWaalsContact CG2-CZ 3.43Å; T152-R156 WeakPolarHBondContact O-CB 3.45Å; T152-R156 VanDerWaalsContact O-CG 3.29Å; T152-R156 WeakPolarHBondContact O-CG 3.4Å; T152-R156 PolarHBondContact O-N 3.29Å; L153-R156 PolarHBondContact O-N 3.23Å; A154-R156 PolarHBondContact O-N 3.44Å; R156-A160 WeakPolarHBondContact O-CB 3.49Å; R156-A160 PolarHBondContact O-N 3.02Å; R156-V315 VanDerWaalsContact CZ-CG2 3.43Å; R156-V315 VanDerWaalsContact NH2-CG1 3.3Å; R156-N476 PolarHBondContact NH2-OD1 3.14Å
157	L	80.8	Confident	75.7	Confident	1 Å²	1	31.1 Å²	31.1	1%	0.005	17%	0.17	C	C	.	.	H	α-helix	trans	-72	-38.8	-179.5	-73.7	-174.7	0	0	0	111.7	L153 A154 A160 A161 M175 I237 I240	L153-L157 HydrophobicContact CD1-CD1 3.53Å; L153-L157 HydrophobicContact CD1-CG 3.81Å; L153-L157 HydrophobicContact CG-CD1 3.97Å; L153-L157 HydrophobicContact CG-CG 4.43Å; L153-L157 WeakPolarHBondContact O-CB 3.37Å; L153-L157 PolarHBondContact O-N 3.49Å; A154-L157 PolarHBondContact O-N 3.08Å; L157-A160 PolarHBondContact O-N 3.26Å; L157-A161 WeakPolarHBondContact O-CB 3.47Å; L157-A161 PolarHBondContact O-N 2.87Å; L157-M175 HydrophobicContact CD2-CG 3.63Å; L157-M175 HydrophobicContact CD2-SD 3.72Å; L157-I237 HydrophobicContact CD1-CG1 3.67Å; L157-I240 HydrophobicContact CB-CD1 3.53Å; L157-I240 HydrophobicContact CB-CG2 4.48Å; L157-I240 HydrophobicContact CD1-CD1 4.14Å; L157-I240 HydrophobicContact CG-CD1 4.49Å
158	S	76	Confident	76.1	Confident	0 Å²	0	33.7 Å²	33.7	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-64	-44.1	174.6	-67.4	0	0	0	0	111.7	A154 A160 A161 N162 D251	A154-S158 WeakPolarHBondContact O-CB 3.34Å; A154-S158 PolarHBondContact O-N 2.67Å; A154-S158 PolarHBondContact O-OG 3.28Å; S158-A160 VanDerWaalsContact C-N 3.34Å; S158-A160 PolarHBondContact O-N 3.37Å; S158-A161 WeakPolarHBondContact O-CB 3.33Å; S158-A161 PolarHBondContact O-N 3.4Å; S158-A161 VanDerWaalsContact O-N 3.14Å; S158-N162 WeakPolarHBondContact O-CB 3.31Å; S158-N162 VanDerWaalsContact O-CG 3.29Å; S158-N162 PolarHBondContact O-N 3.28Å; S158-N162 PolarHBondContact O-ND2 2.89Å; S158-D251 WeakPolarHBondContact CB-OD1 3.25Å; S158-D251 PolarHBondContact OG-OD1 2.78Å
159	T	72.5	Confident	76	Confident	66 Å²	66	38.1 Å²	38.1	41%	0.405	21%	0.213	S	C	.	.	H	α-helix	trans	-58.2	-47.1	174.8	-61.2	0	0	0	0	110.8	S155 A161 N162 I163	S155-T159 VanDerWaalsContact O-CB 3.28Å; S155-T159 WeakPolarHBondContact O-CB 3.46Å; S155-T159 PolarHBondContact O-N 3.06Å; S155-T159 PolarHBondContact O-OG1 3.45Å; T159-A161 VanDerWaalsContact C-N 3.35Å; T159-A161 PolarHBondContact O-N 3.03Å; T159-N162 PolarHBondContact O-N 3.02Å; T159-I163 HydrophobicContact CG2-CD1 3.65Å; T159-I163 HydrophobicContact CG2-CG1 4.5Å; T159-I163 VanDerWaalsContact O-CG1 3.26Å; T159-I163 WeakPolarHBondContact O-CG1 3.4Å; T159-I163 PolarHBondContact O-N 3.18Å
160	A	75.7	Confident	76	Confident	8 Å²	8	46.3 Å²	46.3	7%	0.066	25%	0.249	C	C	.	.	H	α-helix	trans	-64.3	-36	176	0	0	0	0	0	113.7	R156 L157 S158 N162 G164 H165 M166 M175	R156-A160 WeakPolarHBondContact O-CB 3.49Å; R156-A160 PolarHBondContact O-N 3.02Å; L157-A160 PolarHBondContact O-N 3.26Å; S158-A160 VanDerWaalsContact C-N 3.34Å; S158-A160 PolarHBondContact O-N 3.37Å; A160-N162 VanDerWaalsContact C-N 3.35Å; A160-G164 PolarHBondContact O-N 3.11Å; A160-H165 HydrophobicContact CB-CB 4.37Å; A160-H165 PolarHBondContact O-N 2.99Å; A160-M166 HydrophobicContact CB-CG 4.24Å; A160-M166 HydrophobicContact CB-SD 4.08Å; A160-M175 HydrophobicContact CB-CE 3.57Å; A160-M175 HydrophobicContact CB-SD 3.27Å; A160-M175 WeakPolarHBondContact CB-SD 3.5Å
161	A	74.7	Confident	75.9	Confident	4 Å²	4	49.7 Å²	49.7	3%	0.033	27%	0.265	C	S	.	.	H	α-helix	trans	-65.7	-39.6	176.5	0	0	0	0	0	111.7	L157 S158 T159 M166 I240 R244 P250	L157-A161 WeakPolarHBondContact O-CB 3.47Å; L157-A161 PolarHBondContact O-N 2.87Å; S158-A161 WeakPolarHBondContact O-CB 3.33Å; S158-A161 PolarHBondContact O-N 3.4Å; S158-A161 VanDerWaalsContact O-N 3.14Å; T159-A161 VanDerWaalsContact C-N 3.35Å; T159-A161 PolarHBondContact O-N 3.03Å; A161-M166 VanDerWaalsContact CA-SD 3.51Å; A161-M166 HydrophobicContact CB-SD 3.55Å; A161-M166 VanDerWaalsContact CB-SD 3.55Å; A161-M166 PolarHBondContact N-SD 3.19Å; A161-M166 VanDerWaalsContact N-SD 3.38Å; A161-I240 HydrophobicContact CB-CG2 4.17Å; A161-R244 PolarHBondContact O-NE 3.37Å; A161-R244 PolarHBondContact O-NH2 3.26Å; A161-P250 HydrophobicContact CB-CG 4.28Å
162	N	72.7	Confident	76.2	Confident	79 Å²	79	50.6 Å²	50.6	42%	0.422	27%	0.269	S	S	.	.	H	α-helix	trans	-74.5	-33.5	-179.2	-73	-19.2	0	0	0	112.3	S158 T159 A160 G164 N249 D251	S158-N162 WeakPolarHBondContact O-CB 3.31Å; S158-N162 VanDerWaalsContact O-CG 3.29Å; S158-N162 PolarHBondContact O-N 3.28Å; S158-N162 PolarHBondContact O-ND2 2.89Å; T159-N162 PolarHBondContact O-N 3.02Å; A160-N162 VanDerWaalsContact C-N 3.35Å; N162-G164 VanDerWaalsContact C-N 3.3Å; N162-G164 PolarHBondContact O-N 3.45Å; N162-N249 PolarHBondContact ND2-OD1 3.43Å; N162-D251 PolarHBondContact ND2-OD2 3.1Å; N162-D251 VanDerWaalsContact ND2-OD2 3.14Å
163	I	73.6	Confident	76.5	Confident	96 Å²	96	57.3 Å²	57.3	49%	0.492	29%	0.292	S	S	.	.	H	α-helix	trans	-77.2	-14.8	176.5	-64.5	168	0	0	0	112.4	T159	T159-I163 HydrophobicContact CG2-CD1 3.65Å; T159-I163 HydrophobicContact CG2-CG1 4.5Å; T159-I163 VanDerWaalsContact O-CG1 3.26Å; T159-I163 WeakPolarHBondContact O-CG1 3.4Å; T159-I163 PolarHBondContact O-N 3.18Å
164	G	69.4	Low	76.7	Confident	17 Å²	17	63.7 Å²	63.7	18%	0.175	32%	0.316	C	S	.	.	T	Hydrogen-bonded Turn	trans	90.3	3.9	-177.3	0	0	0	0	0	114.2	A160 N162 M166 D167	A160-G164 PolarHBondContact O-N 3.11Å; N162-G164 VanDerWaalsContact C-N 3.3Å; N162-G164 PolarHBondContact O-N 3.45Å; G164-M166 PolarHBondContact O-N 3.31Å; G164-D167 WeakPolarHBondContact O-CB 3.28Å; G164-D167 PolarHBondContact O-N 3.44Å; G164-D167 VanDerWaalsContact O-N 3.12Å; G164-D167 VanDerWaalsContact O-OD2 3.09Å
165	H	67.5	Low	76.8	Confident	112 Å²	112	65.4 Å²	65.4	52%	0.519	33%	0.325	S	S	.	.	T	Hydrogen-bonded Turn	trans	-68.3	1.2	176	-72.3	-172.2	0	0	0	114	A160 M175	A160-H165 HydrophobicContact CB-CB 4.37Å; A160-H165 PolarHBondContact O-N 2.99Å; H165-M175 HydrophobicContact CB-CE 4.24Å
166	M	66.9	Low	77.5	Confident	9 Å²	9	64.1 Å²	64.1	4%	0.044	31%	0.314	C	S	.	.	T	Hydrogen-bonded Turn	trans	-112	14.1	176.7	-69.5	173.7	77.6	0	0	112.7	A160 A161 G164 L172 M175 I240 R244	A160-M166 HydrophobicContact CB-CG 4.24Å; A160-M166 HydrophobicContact CB-SD 4.08Å; A161-M166 VanDerWaalsContact CA-SD 3.51Å; A161-M166 HydrophobicContact CB-SD 3.55Å; A161-M166 VanDerWaalsContact CB-SD 3.55Å; A161-M166 PolarHBondContact N-SD 3.19Å; A161-M166 VanDerWaalsContact N-SD 3.38Å; G164-M166 PolarHBondContact O-N 3.31Å; M166-L172 HydrophobicContact CB-CD1 4.14Å; M166-L172 HydrophobicContact CE-CD1 3.12Å; M166-L172 HydrophobicContact CG-CD1 4.09Å; M166-L172 HydrophobicContact SD-CD1 4.38Å; M166-M175 HydrophobicContact CG-SD 4.15Å; M166-M175 HydrophobicContact SD-SD 4.36Å; M166-I240 HydrophobicContact CE-CG2 4.31Å; M166-R244 PolarHBondContact O-NH1 2.94Å
167	D	69.8	Low	78.1	Confident	107 Å²	107	63.6 Å²	63.6	57%	0.572	32%	0.318	S	S	*	.	S	Bend	trans	-74.4	-32.1	-177.1	-71.3	-20	0	0	0	113.5	G164 R244	G164-D167 WeakPolarHBondContact O-CB 3.28Å; G164-D167 PolarHBondContact O-N 3.44Å; G164-D167 VanDerWaalsContact O-N 3.12Å; G164-D167 VanDerWaalsContact O-OD2 3.09Å; D167-R244 IonicContact OD1-CZ 2.91Å; D167-R244 IonicContact OD1-NH1 2.76Å; D167-R244 PolarHBondContact OD1-NH1 3.14Å; D167-R244 IonicContact OD1-NH2 3.97Å; D167-R244 PolarHBondContact OD1-NH2 2.94Å
168	T	79.5	Confident	78.6	Confident	60 Å²	60	63.6 Å²	63.6	37%	0.368	32%	0.319	S	S	.	.	S	Bend	trans	-92.3	135.4	174.3	75.2	0	0	0	0	111.1	K170 E171 L172	T168-K170 PolarHBondContact O-N 3.09Å; T168-K170 VanDerWaalsContact O-N 3.12Å; T168-E171 PolarHBondContact O-N 2.89Å; T168-E171 VanDerWaalsContact O-N 3.13Å; T168-E171 VanDerWaalsContact OG1-CB 3.26Å; T168-E171 WeakPolarHBondContact OG1-CB 3.4Å; T168-E171 WeakPolarHBondContact OG1-CG 3.28Å; T168-E171 PolarHBondContact OG1-N 2.99Å; T168-E171 PolarHBondContact OG1-OE2 2.94Å; T168-L172 WeakPolarHBondContact O-CB 3.47Å; T168-L172 PolarHBondContact O-N 2.66Å
169	P	80.5	Confident	79.2	Confident	95 Å²	95	64.1 Å²	64.1	62%	0.617	32%	0.321	S	S	*	.	H	α-helix	trans	-55.7	-33.3	177.1	-27	33.9	0	0	0	113	W173	P169-W173 WeakPolarHBondContact O-CB 3.28Å; P169-W173 PolarHBondContact O-N 2.89Å
170	K	83.5	Confident	80.1	Confident	178 Å²	178	61.5 Å²	61.5	77%	0.774	31%	0.305	S	S	*	.	H	α-helix	trans	-67.6	-43.3	179.6	-172.8	179.9	179.2	-176.8	0	111.9	T168 R174	T168-K170 PolarHBondContact O-N 3.09Å; T168-K170 VanDerWaalsContact O-N 3.12Å; K170-R174 VanDerWaalsContact O-CB 3.28Å; K170-R174 WeakPolarHBondContact O-CB 3.4Å; K170-R174 PolarHBondContact O-N 3.36Å
171	E	81.3	Confident	81	Confident	74 Å²	74	61.1 Å²	61.1	35%	0.346	30%	0.302	S	S	.	.	H	α-helix	trans	-70.9	-41.5	178	-71.4	164.7	158.5	0	0	111.3	T168 R174 M175	T168-E171 PolarHBondContact O-N 2.89Å; T168-E171 VanDerWaalsContact O-N 3.13Å; T168-E171 VanDerWaalsContact OG1-CB 3.26Å; T168-E171 WeakPolarHBondContact OG1-CB 3.4Å; T168-E171 WeakPolarHBondContact OG1-CG 3.28Å; T168-E171 PolarHBondContact OG1-N 2.99Å; T168-E171 PolarHBondContact OG1-OE2 2.94Å; E171-R174 PolarHBondContact O-N 3.26Å; E171-M175 VanDerWaalsContact O-CB 3.3Å; E171-M175 WeakPolarHBondContact O-CB 3.14Å; E171-M175 PolarHBondContact O-N 2.9Å
172	L	83.5	Confident	81.8	Confident	30 Å²	30	61 Å²	61	16%	0.157	30%	0.3	C	S	.	.	H	α-helix	trans	-53.3	-56	173.2	176.1	61.1	0	0	0	111.4	M166 T168 R174 M175 I176 I241	M166-L172 HydrophobicContact CB-CD1 4.14Å; M166-L172 HydrophobicContact CE-CD1 3.12Å; M166-L172 HydrophobicContact CG-CD1 4.09Å; M166-L172 HydrophobicContact SD-CD1 4.38Å; T168-L172 WeakPolarHBondContact O-CB 3.47Å; T168-L172 PolarHBondContact O-N 2.66Å; L172-R174 PolarHBondContact O-N 3.49Å; L172-M175 PolarHBondContact O-N 3.49Å; L172-I176 HydrophobicContact CD1-CD1 3.56Å; L172-I176 HydrophobicContact CD1-CG1 4.19Å; L172-I176 HydrophobicContact CG-CD1 3.71Å; L172-I176 WeakPolarHBondContact O-CB 3.47Å; L172-I176 VanDerWaalsContact O-CG1 3.27Å; L172-I176 WeakPolarHBondContact O-CG1 3.33Å; L172-I176 PolarHBondContact O-N 3.42Å; L172-I241 HydrophobicContact CD1-CD1 4.32Å; L172-I241 HydrophobicContact CD1-CG1 4.38Å; L172-I241 HydrophobicContact CD2-CD1 4.36Å
173	W	85.2	Confident	82.7	Confident	166 Å²	166	57.5 Å²	57.5	63%	0.629	28%	0.282	S	S	*	.	H	α-helix	trans	-64	-40.8	179.7	-81	112.9	0	0	0	112.4	P169 M175 I176 T177	P169-W173 WeakPolarHBondContact O-CB 3.28Å; P169-W173 PolarHBondContact O-N 2.89Å; W173-M175 VanDerWaalsContact C-N 3.3Å; W173-M175 PolarHBondContact O-N 3.28Å; W173-I176 HydrophobicContact CE3-CG2 4.46Å; W173-I176 PolarHBondContact O-N 2.86Å; W173-T177 VanDerWaalsContact O-CB 3.25Å; W173-T177 WeakPolarHBondContact O-CB 3.33Å; W173-T177 PolarHBondContact O-N 3.04Å; W173-T177 PolarHBondContact O-OG1 3.43Å
174	R	85.7	Confident	83.7	Confident	136 Å²	136	53 Å²	53	51%	0.513	26%	0.258	S	S	.	.	H	α-helix	trans	-60.2	-42.2	176.5	-178.7	176.9	64.3	179.9	-2.4	111.6	K170 E171 L172 G178	K170-R174 VanDerWaalsContact O-CB 3.28Å; K170-R174 WeakPolarHBondContact O-CB 3.4Å; K170-R174 PolarHBondContact O-N 3.36Å; E171-R174 PolarHBondContact O-N 3.26Å; L172-R174 PolarHBondContact O-N 3.49Å; R174-G178 PolarHBondContact O-N 3.32Å
175	M	83.9	Confident	84.9	Confident	37 Å²	37	52.3 Å²	52.3	18%	0.182	25%	0.251	C	S	.	.	H	α-helix	trans	-71.1	-44.6	-179.7	-172.2	178.4	-68.9	0	0	111.8	L157 A160 H165 M166 E171 L172 W173 G178 N179	L157-M175 HydrophobicContact CD2-CG 3.63Å; L157-M175 HydrophobicContact CD2-SD 3.72Å; A160-M175 HydrophobicContact CB-CE 3.57Å; A160-M175 HydrophobicContact CB-SD 3.27Å; A160-M175 WeakPolarHBondContact CB-SD 3.5Å; H165-M175 HydrophobicContact CB-CE 4.24Å; M166-M175 HydrophobicContact CG-SD 4.15Å; M166-M175 HydrophobicContact SD-SD 4.36Å; E171-M175 VanDerWaalsContact O-CB 3.3Å; E171-M175 WeakPolarHBondContact O-CB 3.14Å; E171-M175 PolarHBondContact O-N 2.9Å; L172-M175 PolarHBondContact O-N 3.49Å; W173-M175 VanDerWaalsContact C-N 3.3Å; W173-M175 PolarHBondContact O-N 3.28Å; M175-G178 PolarHBondContact O-N 2.99Å; M175-N179 WeakPolarHBondContact CG-ND2 3.27Å; M175-N179 WeakPolarHBondContact O-CB 3.48Å; M175-N179 PolarHBondContact O-N 3.45Å; M175-N179 PolarHBondContact O-ND2 3.3Å
176	I	87.7	Confident	86.2	Confident	10 Å²	10	47.5 Å²	47.5	5%	0.051	23%	0.229	C	C	.	.	H	α-helix	trans	-57.4	-54.2	174.5	-75.6	165.6	0	0	0	110.1	L172 W173 G178 N179 M180 I237 I241	L172-I176 HydrophobicContact CD1-CD1 3.56Å; L172-I176 HydrophobicContact CD1-CG1 4.19Å; L172-I176 HydrophobicContact CG-CD1 3.71Å; L172-I176 WeakPolarHBondContact O-CB 3.47Å; L172-I176 VanDerWaalsContact O-CG1 3.27Å; L172-I176 WeakPolarHBondContact O-CG1 3.33Å; L172-I176 PolarHBondContact O-N 3.42Å; W173-I176 HydrophobicContact CE3-CG2 4.46Å; W173-I176 PolarHBondContact O-N 2.86Å; I176-G178 VanDerWaalsContact C-N 3.33Å; I176-G178 PolarHBondContact O-N 3.23Å; I176-N179 PolarHBondContact O-N 3.29Å; I176-M180 WeakPolarHBondContact O-CB 3.3Å; I176-M180 PolarHBondContact O-N 3.06Å; I176-I237 HydrophobicContact CB-CD1 4.41Å; I176-I237 HydrophobicContact CD1-CG2 3.62Å; I176-I237 HydrophobicContact CG1-CD1 4.38Å; I176-I237 HydrophobicContact CG1-CG1 4.31Å; I176-I237 HydrophobicContact CG1-CG2 3.81Å; I176-I237 HydrophobicContact CG2-CD1 3.61Å; I176-I237 HydrophobicContact CG2-CG1 4.42Å; I176-I237 HydrophobicContact CG2-CG2 4.34Å; I176-I241 HydrophobicContact CD1-CD1 3.95Å
177	T	90.5	Very high	87.5	Confident	50 Å²	50	47.1 Å²	47.1	31%	0.307	23%	0.227	S	C	.	.	H	α-helix	trans	-65.1	-38.4	-176.4	-59.7	0	0	0	0	111.7	W173 A181 L305	W173-T177 VanDerWaalsContact O-CB 3.25Å; W173-T177 WeakPolarHBondContact O-CB 3.33Å; W173-T177 PolarHBondContact O-N 3.04Å; W173-T177 PolarHBondContact O-OG1 3.43Å; T177-A181 WeakPolarHBondContact O-CB 3.48Å; T177-A181 PolarHBondContact O-N 3.41Å; T177-L305 HydrophobicContact CG2-CD1 3.57Å; T177-L305 HydrophobicContact CG2-CD2 3.54Å; T177-L305 HydrophobicContact CG2-CG 3.64Å
178	G	90.4	Very high	88.7	Confident	2 Å²	2	42.1 Å²	42.1	2%	0.021	20%	0.2	C	C	.	.	H	α-helix	trans	-65.2	-48.2	176.3	0	0	0	0	0	113	R174 M175 I176 A181 L182 T312	R174-G178 PolarHBondContact O-N 3.32Å; M175-G178 PolarHBondContact O-N 2.99Å; I176-G178 VanDerWaalsContact C-N 3.33Å; I176-G178 PolarHBondContact O-N 3.23Å; G178-A181 PolarHBondContact O-N 2.86Å; G178-L182 WeakPolarHBondContact O-CB 3.26Å; G178-L182 PolarHBondContact O-N 3.31Å; G178-T312 WeakPolarHBondContact O-CG2 3.32Å
179	N	88.9	Confident	89.4	Confident	10 Å²	10	41.1 Å²	41.1	5%	0.053	19%	0.194	C	C	.	.	H	α-helix	trans	-70.2	-40.5	179.9	-77.4	-77.8	0	0	0	112.2	L153 M175 I176 A181 L182 I183 T312	L153-N179 HydrophobicContact CD1-CB 3.51Å; M175-N179 WeakPolarHBondContact CG-ND2 3.27Å; M175-N179 WeakPolarHBondContact O-CB 3.48Å; M175-N179 PolarHBondContact O-N 3.45Å; M175-N179 PolarHBondContact O-ND2 3.3Å; I176-N179 PolarHBondContact O-N 3.29Å; N179-A181 VanDerWaalsContact C-N 3.32Å; N179-A181 PolarHBondContact O-N 3.1Å; N179-L182 PolarHBondContact O-N 3.09Å; N179-I183 WeakPolarHBondContact O-CG1 3.27Å; N179-I183 PolarHBondContact O-N 3.48Å; N179-T312 HydrophobicContact CB-CG2 4.35Å
180	M	91.9	Very high	90.1	Very high	12 Å²	12	36.6 Å²	36.6	6%	0.059	17%	0.165	C	C	.	.	H	α-helix	trans	-58.6	-46.7	173.1	-178.6	59.1	70.5	0	0	110.6	I176 L182 I183 Q184 L230 M234 I237	I176-M180 WeakPolarHBondContact O-CB 3.3Å; I176-M180 PolarHBondContact O-N 3.06Å; M180-L182 PolarHBondContact O-N 3.23Å; M180-I183 PolarHBondContact O-N 3.46Å; M180-Q184 WeakPolarHBondContact O-CG 3.48Å; M180-Q184 PolarHBondContact O-N 3.36Å; M180-Q184 HydrophobicContact SD-CG 4.48Å; M180-L230 HydrophobicContact CG-CD1 4.38Å; M180-L230 HydrophobicContact SD-CD1 3.8Å; M180-M234 HydrophobicContact CE-CG 3.84Å; M180-M234 HydrophobicContact CE-SD 3.78Å; M180-I237 HydrophobicContact CE-CD1 3.64Å
181	A	93.8	Very high	90.6	Very high	0 Å²	0	28.1 Å²	28.1	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-62.2	-42.1	177.5	0	0	0	0	0	112.9	T177 G178 N179 I183 Q184 V185 W302 L305 A306	T177-A181 WeakPolarHBondContact O-CB 3.48Å; T177-A181 PolarHBondContact O-N 3.41Å; G178-A181 PolarHBondContact O-N 2.86Å; N179-A181 VanDerWaalsContact C-N 3.32Å; N179-A181 PolarHBondContact O-N 3.1Å; A181-I183 VanDerWaalsContact C-N 3.33Å; A181-I183 PolarHBondContact O-N 3.36Å; A181-Q184 PolarHBondContact O-N 3.05Å; A181-V185 WeakPolarHBondContact O-CG2 3.35Å; A181-V185 PolarHBondContact O-N 3.38Å; A181-W302 HydrophobicContact CB-CE3 3.74Å; A181-W302 HydrophobicContact CB-CZ3 4.36Å; A181-L305 HydrophobicContact CB-CB 3.75Å; A181-L305 HydrophobicContact CB-CD2 3.97Å; A181-L305 HydrophobicContact CB-CG 3.76Å; A181-A306 HydrophobicContact CB-CB 3.99Å
182	L	92	Very high	91.3	Very high	1 Å²	1	28.8 Å²	28.8	1%	0.005	13%	0.13	C	C	.	.	H	α-helix	trans	-58.4	-46.6	176.5	175.4	64.7	0	0	0	111.3	G178 N179 M180 V185 Q186 A306 T312 V315 L316	G178-L182 WeakPolarHBondContact O-CB 3.26Å; G178-L182 PolarHBondContact O-N 3.31Å; N179-L182 PolarHBondContact O-N 3.09Å; M180-L182 PolarHBondContact O-N 3.23Å; L182-V185 WeakPolarHBondContact O-CB 3.4Å; L182-V185 PolarHBondContact O-N 2.67Å; L182-Q186 HydrophobicContact CD1-CG 4.4Å; L182-Q186 WeakPolarHBondContact O-CG 2.93Å; L182-Q186 PolarHBondContact O-N 2.93Å; L182-A306 HydrophobicContact CB-CB 4.27Å; L182-T312 HydrophobicContact CB-CG2 4.24Å; L182-T312 HydrophobicContact CD2-CG2 4.09Å; L182-V315 HydrophobicContact CD2-CB 3.82Å; L182-V315 HydrophobicContact CD2-CG1 3.77Å; L182-L316 HydrophobicContact CD1-CB 3.91Å; L182-L316 HydrophobicContact CD1-CD1 3.99Å
183	I	92	Very high	91.9	Very high	6 Å²	6	29.9 Å²	29.9	3%	0.031	14%	0.135	C	C	.	.	H	α-helix	trans	-63.6	-42.9	178.5	-71.6	166.4	0	0	0	111.1	L149 L153 N179 M180 A181 V185 Q186 A187	L149-I183 HydrophobicContact CB-CG2 4.37Å; L149-I183 HydrophobicContact CD1-CG2 4.31Å; L153-I183 HydrophobicContact CB-CD1 3.56Å; L153-I183 HydrophobicContact CD1-CD1 3.7Å; L153-I183 HydrophobicContact CD2-CD1 3.52Å; L153-I183 HydrophobicContact CG-CD1 3.74Å; N179-I183 WeakPolarHBondContact O-CG1 3.27Å; N179-I183 PolarHBondContact O-N 3.48Å; M180-I183 PolarHBondContact O-N 3.46Å; A181-I183 VanDerWaalsContact C-N 3.33Å; A181-I183 PolarHBondContact O-N 3.36Å; I183-V185 VanDerWaalsContact C-N 3.27Å; I183-V185 PolarHBondContact O-N 3.03Å; I183-Q186 PolarHBondContact O-N 2.82Å; I183-A187 WeakPolarHBondContact O-CB 3.35Å; I183-A187 PolarHBondContact O-N 3.41Å
184	Q	94.7	Very high	92.4	Very high	0 Å²	0	22 Å²	22	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-60	-39.1	176.5	-68.8	-51.5	-48.9	0	0	112	M180 A181 T188 F226 S229 W302	M180-Q184 WeakPolarHBondContact O-CG 3.48Å; M180-Q184 PolarHBondContact O-N 3.36Å; M180-Q184 HydrophobicContact SD-CG 4.48Å; A181-Q184 PolarHBondContact O-N 3.05Å; Q184-T188 WeakPolarHBondContact O-CB 3.36Å; Q184-T188 PolarHBondContact O-N 3.42Å; Q184-T188 PolarHBondContact O-OG1 2.89Å; Q184-F226 HydrophobicContact CB-CE2 4.39Å; Q184-F226 VanDerWaalsContact OE1-CG 3.3Å; Q184-F226 PolarHBondContact OE1-O 3.12Å; Q184-S229 PolarHBondContact NE2-OG 2.79Å; Q184-S229 VanDerWaalsContact NE2-OG 3.1Å; Q184-W302 HydrophobicContact CB-CB 4.29Å; Q184-W302 HydrophobicContact CB-CD2 3.69Å; Q184-W302 HydrophobicContact CB-CE3 4.16Å; Q184-W302 HydrophobicContact CB-CG 3.75Å; Q184-W302 HydrophobicContact CB-CZ2 4.49Å; Q184-W302 HydrophobicContact CG-CD2 4.02Å; Q184-W302 HydrophobicContact CG-CE3 4.21Å; Q184-W302 HydrophobicContact CG-CH2 4.18Å; Q184-W302 HydrophobicContact CG-CZ2 4.01Å; Q184-W302 HydrophobicContact CG-CZ3 4.28Å
185	V	94.5	Very high	92.9	Very high	3 Å²	3	15.7 Å²	15.7	2%	0.018	8%	0.083	C	C	.	.	H	α-helix	trans	-63.3	-51.1	173.7	175.5	0	0	0	0	110.8	A181 L182 I183 T188 V189 W302 V303 L316 W320	A181-V185 WeakPolarHBondContact O-CG2 3.35Å; A181-V185 PolarHBondContact O-N 3.38Å; L182-V185 WeakPolarHBondContact O-CB 3.4Å; L182-V185 PolarHBondContact O-N 2.67Å; I183-V185 VanDerWaalsContact C-N 3.27Å; I183-V185 PolarHBondContact O-N 3.03Å; V185-T188 PolarHBondContact O-N 3.07Å; V185-V189 WeakPolarHBondContact O-CG2 2.99Å; V185-V189 PolarHBondContact O-N 3.48Å; V185-V189 VanDerWaalsContact O-N 3.08Å; V185-W302 HydrophobicContact CG2-CB 3.48Å; V185-W302 VanDerWaalsContact CG2-CB 3.48Å; V185-V303 HydrophobicContact CG1-CG2 3.95Å; V185-V303 HydrophobicContact CG2-CB 4.42Å; V185-V303 HydrophobicContact CG2-CG2 3.68Å; V185-L316 HydrophobicContact CB-CD1 4.48Å; V185-L316 HydrophobicContact CG1-CD1 3.92Å; V185-W320 HydrophobicContact CG1-CH2 3.87Å; V185-W320 HydrophobicContact CG1-CZ2 4.06Å
186	Q	93.6	Very high	93.4	Very high	11 Å²	11	17.6 Å²	17.6	5%	0.051	9%	0.093	C	C	.	.	H	α-helix	trans	-64	-44.2	-178.2	-69.7	179.8	-59	0	0	111.7	L149 L182 I183 T188 V189 V190 W320	L149-Q186 HydrophobicContact CD1-CB 4Å; L149-Q186 HydrophobicContact CD2-CB 3.64Å; L149-Q186 HydrophobicContact CD2-CG 4.29Å; L182-Q186 HydrophobicContact CD1-CG 4.4Å; L182-Q186 WeakPolarHBondContact O-CG 2.93Å; L182-Q186 PolarHBondContact O-N 2.93Å; I183-Q186 PolarHBondContact O-N 2.82Å; Q186-T188 PolarHBondContact O-N 3.28Å; Q186-V189 PolarHBondContact O-N 3.06Å; Q186-V190 WeakPolarHBondContact O-CB 3.3Å; Q186-V190 WeakPolarHBondContact O-CG2 3.34Å; Q186-V190 PolarHBondContact O-N 2.74Å; Q186-W320 HydrophobicContact CG-CH2 4.22Å; Q186-W320 HydrophobicContact CG-CZ3 4.28Å
187	A	94.3	Very high	93.8	Very high	1 Å²	1	17.9 Å²	17.9	1%	0.008	10%	0.097	C	C	.	.	H	α-helix	trans	-62.5	-43.6	178.9	0	0	0	0	0	112.1	L149 I183 G191 A225 S229	L149-A187 HydrophobicContact CD1-CB 3.91Å; I183-A187 WeakPolarHBondContact O-CB 3.35Å; I183-A187 PolarHBondContact O-N 3.41Å; A187-G191 WeakPolarHBondContact O-CA 3.26Å; A187-G191 PolarHBondContact O-N 3.38Å; A187-A225 HydrophobicContact CB-CB 4.23Å; A187-A225 WeakPolarHBondContact CB-O 3.5Å; A187-A225 VanDerWaalsContact O-CB 3.27Å; A187-A225 WeakPolarHBondContact O-CB 3.43Å; A187-S229 VanDerWaalsContact CB-OG 3.26Å; A187-S229 WeakPolarHBondContact CB-OG 3.32Å
188	T	94.9	Very high	94	Very high	2 Å²	2	15.5 Å²	15.5	1%	0.012	8%	0.082	C	C	.	.	H	α-helix	trans	-63.9	-49.4	177.7	-53.9	0	0	0	0	111.4	Q184 V185 Q186 F192 V222 F226 L299	Q184-T188 WeakPolarHBondContact O-CB 3.36Å; Q184-T188 PolarHBondContact O-N 3.42Å; Q184-T188 PolarHBondContact O-OG1 2.89Å; V185-T188 PolarHBondContact O-N 3.07Å; Q186-T188 PolarHBondContact O-N 3.28Å; T188-F192 WeakPolarHBondContact O-CB 3.39Å; T188-F192 PolarHBondContact O-N 3.16Å; T188-V222 HydrophobicContact CG2-CG1 3.93Å; T188-F226 WeakPolarHBondContact OG1-CD2 3.49Å; T188-L299 HydrophobicContact CG2-CD1 4.23Å
189	V	94.8	Very high	94.2	Very high	39 Å²	39	16.6 Å²	16.6	24%	0.236	9%	0.088	C	C	.	.	H	α-helix	trans	-67.5	-47.2	-177.6	173.1	0	0	0	0	110.8	V185 Q186 F192 L193 L299 W320	V185-V189 WeakPolarHBondContact O-CG2 2.99Å; V185-V189 PolarHBondContact O-N 3.48Å; V185-V189 VanDerWaalsContact O-N 3.08Å; Q186-V189 PolarHBondContact O-N 3.06Å; V189-F192 WeakPolarHBondContact O-CB 3.35Å; V189-F192 PolarHBondContact O-N 3.5Å; V189-L193 HydrophobicContact CG1-CD1 4.14Å; V189-L193 WeakPolarHBondContact O-CG 3.32Å; V189-L193 PolarHBondContact O-N 3.33Å; V189-L299 HydrophobicContact CG2-CD1 3.61Å; V189-W320 HydrophobicContact CB-CH2 3.96Å; V189-W320 HydrophobicContact CB-CZ3 3.81Å; V189-W320 HydrophobicContact CG1-CH2 4.11Å; V189-W320 HydrophobicContact CG1-CZ3 3.67Å; V189-W320 HydrophobicContact CG2-CH2 3.96Å; V189-W320 HydrophobicContact CG2-CZ3 4.32Å
190	V	94.4	Very high	94.5	Very high	0 Å²	0	19.1 Å²	19.1	0%	0	10%	0.104	C	C	.	.	H	α-helix	trans	-74	-33.9	-176.4	-176.1	0	0	0	0	110.8	L145 Q186 F192 L193 A194 W320 V323 M327	L145-V190 HydrophobicContact CD1-CB 3.73Å; L145-V190 HydrophobicContact CD1-CG1 3.5Å; L145-V190 VanDerWaalsContact CD1-CG1 3.5Å; L145-V190 HydrophobicContact CD1-CG2 4.22Å; L145-V190 HydrophobicContact CD2-CB 3.98Å; L145-V190 HydrophobicContact CD2-CG1 3.96Å; L145-V190 HydrophobicContact CG-CG1 4.27Å; Q186-V190 WeakPolarHBondContact O-CB 3.3Å; Q186-V190 WeakPolarHBondContact O-CG2 3.34Å; Q186-V190 PolarHBondContact O-N 2.74Å; V190-F192 VanDerWaalsContact C-N 3.33Å; V190-F192 PolarHBondContact O-N 2.82Å; V190-L193 PolarHBondContact O-N 2.97Å; V190-A194 VanDerWaalsContact O-CB 3.27Å; V190-A194 WeakPolarHBondContact O-CB 3.41Å; V190-A194 PolarHBondContact O-N 3.29Å; V190-W320 HydrophobicContact CG2-CZ3 4.42Å; V190-V323 HydrophobicContact CB-CG1 4.48Å; V190-V323 HydrophobicContact CG1-CG1 4.29Å; V190-V323 HydrophobicContact CG2-CG1 3.62Å; V190-M327 HydrophobicContact CG1-CB 3.75Å; V190-M327 HydrophobicContact CG1-CG 3.68Å
191	G	95.6	Very high	94.6	Very high	0 Å²	0	20.8 Å²	20.8	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-59.8	-42.6	169	0	0	0	0	0	112.1	A187 A194 S195 S221	A187-G191 WeakPolarHBondContact O-CA 3.26Å; A187-G191 PolarHBondContact O-N 3.38Å; G191-A194 PolarHBondContact O-N 3.04Å; G191-S195 PolarHBondContact O-N 3.41Å; G191-S221 VanDerWaalsContact C-OG 3.27Å; G191-S221 WeakPolarHBondContact CA-OG 3.5Å; G191-S221 WeakPolarHBondContact O-CB 3.42Å; G191-S221 PolarHBondContact O-OG 2.84Å
192	F	95.5	Very high	94.4	Very high	88 Å²	88	20.9 Å²	20.9	39%	0.386	11%	0.112	S	C	.	.	H	α-helix	trans	-61.2	-48.4	173.3	177.1	-104.5	0	0	0	111.7	T188 V189 V190 A194 S195 I196 C218 V222	T188-F192 WeakPolarHBondContact O-CB 3.39Å; T188-F192 PolarHBondContact O-N 3.16Å; V189-F192 WeakPolarHBondContact O-CB 3.35Å; V189-F192 PolarHBondContact O-N 3.5Å; V190-F192 VanDerWaalsContact C-N 3.33Å; V190-F192 PolarHBondContact O-N 2.82Å; F192-A194 VanDerWaalsContact C-N 3.33Å; F192-A194 PolarHBondContact O-N 3.2Å; F192-S195 PolarHBondContact O-N 2.98Å; F192-S195 PolarHBondContact O-OG 3.24Å; F192-I196 HydrophobicContact CD1-CD1 3.97Å; F192-I196 HydrophobicContact CE1-CD1 3.39Å; F192-I196 HydrophobicContact CE1-CG1 4.41Å; F192-I196 HydrophobicContact CE2-CD1 4.45Å; F192-I196 HydrophobicContact CZ-CD1 3.67Å; F192-I196 HydrophobicContact CZ-CG1 4.39Å; F192-I196 PolarHBondContact O-N 3.26Å; F192-I196 VanDerWaalsContact O-N 3.16Å; F192-C218 VanDerWaalsContact CD2-SG 3.57Å; F192-V222 HydrophobicContact CB-CG2 3.83Å; F192-V222 HydrophobicContact CD2-CG2 4.49Å
193	L	95.7	Very high	94.4	Very high	53 Å²	53	27.1 Å²	27.1	28%	0.277	14%	0.136	S	C	.	.	H	α-helix	trans	-63.3	-37.7	178.1	-67.3	175.3	0	0	0	112.6	V189 V190 S195 I196 A197 I324 M327	V189-L193 HydrophobicContact CG1-CD1 4.14Å; V189-L193 WeakPolarHBondContact O-CG 3.32Å; V189-L193 PolarHBondContact O-N 3.33Å; V190-L193 PolarHBondContact O-N 2.97Å; L193-S195 VanDerWaalsContact C-N 3.3Å; L193-S195 PolarHBondContact O-N 3.04Å; L193-I196 PolarHBondContact O-N 3.47Å; L193-A197 PolarHBondContact O-N 3.42Å; L193-I324 HydrophobicContact CD1-CD1 4.15Å; L193-I324 HydrophobicContact CD1-CG1 4.04Å; L193-M327 HydrophobicContact CB-CE 3.5Å; L193-M327 VanDerWaalsContact CB-CE 3.5Å
194	A	96.1	Very high	94.3	Very high	1 Å²	1	32.1 Å²	32.1	1%	0.008	16%	0.161	C	C	.	.	H	α-helix	trans	-63	-36.7	175.3	0	0	0	0	0	111.7	L138 A141 V190 G191 F192 A197 A198 M327	L138-A194 HydrophobicContact CD1-CB 3.72Å; A141-A194 HydrophobicContact CB-CB 4.16Å; V190-A194 VanDerWaalsContact O-CB 3.27Å; V190-A194 WeakPolarHBondContact O-CB 3.41Å; V190-A194 PolarHBondContact O-N 3.29Å; G191-A194 PolarHBondContact O-N 3.04Å; F192-A194 VanDerWaalsContact C-N 3.33Å; F192-A194 PolarHBondContact O-N 3.2Å; A194-A197 PolarHBondContact O-N 2.82Å; A194-A198 WeakPolarHBondContact O-CB 3.35Å; A194-A198 PolarHBondContact O-N 3.35Å; A194-M327 VanDerWaalsContact CA-SD 3.57Å; A194-M327 HydrophobicContact CB-CG 3.93Å; A194-M327 HydrophobicContact CB-SD 3.9Å
195	S	95.9	Very high	93.9	Very high	4 Å²	4	35.2 Å²	35.2	3%	0.028	18%	0.181	C	C	.	.	H	α-helix	trans	-66.9	-38.3	174.1	76.1	0	0	0	0	112.5	G191 F192 L193 A198 V199 C218	G191-S195 PolarHBondContact O-N 3.41Å; F192-S195 PolarHBondContact O-N 2.98Å; F192-S195 PolarHBondContact O-OG 3.24Å; L193-S195 VanDerWaalsContact C-N 3.3Å; L193-S195 PolarHBondContact O-N 3.04Å; S195-A198 PolarHBondContact O-N 2.92Å; S195-V199 VanDerWaalsContact O-CG2 3.27Å; S195-V199 WeakPolarHBondContact O-CG2 3.37Å; S195-V199 PolarHBondContact O-N 3.39Å; S195-C218 WeakPolarHBondContact OG-CA 3.22Å
196	I	95.4	Very high	93.2	Very high	76 Å²	76	38.8 Å²	38.8	39%	0.39	20%	0.2	S	C	.	.	H	α-helix	trans	-64.1	-46	173.7	-66.2	171.4	0	0	0	109.7	F192 L193 A198 V199 V200	F192-I196 HydrophobicContact CD1-CD1 3.97Å; F192-I196 HydrophobicContact CE1-CD1 3.39Å; F192-I196 HydrophobicContact CE1-CG1 4.41Å; F192-I196 HydrophobicContact CE2-CD1 4.45Å; F192-I196 HydrophobicContact CZ-CD1 3.67Å; F192-I196 HydrophobicContact CZ-CG1 4.39Å; F192-I196 PolarHBondContact O-N 3.26Å; F192-I196 VanDerWaalsContact O-N 3.16Å; L193-I196 PolarHBondContact O-N 3.47Å; I196-A198 VanDerWaalsContact C-N 3.33Å; I196-A198 PolarHBondContact O-N 3.43Å; I196-V199 PolarHBondContact O-N 2.91Å; I196-V200 HydrophobicContact CG2-CG2 4.25Å; I196-V200 WeakPolarHBondContact O-CB 3.4Å; I196-V200 VanDerWaalsContact O-CG2 3.3Å; I196-V200 WeakPolarHBondContact O-CG2 3.32Å; I196-V200 PolarHBondContact O-N 3.2Å
197	A	95.2	Very high	92.7	Very high	17 Å²	17	40.6 Å²	40.6	14%	0.14	22%	0.222	C	C	.	.	H	α-helix	trans	-59	-44.9	177.4	0	0	0	0	0	111.3	L193 A194 V199 V200 F201 M327	L193-A197 PolarHBondContact O-N 3.42Å; A194-A197 PolarHBondContact O-N 2.82Å; A197-V199 PolarHBondContact O-N 3.21Å; A197-V200 PolarHBondContact O-N 3.2Å; A197-F201 VanDerWaalsContact O-CB 3.29Å; A197-F201 WeakPolarHBondContact O-CB 3.24Å; A197-F201 VanDerWaalsContact O-CG 3.31Å; A197-F201 WeakPolarHBondContact O-CG 3.4Å; A197-F201 PolarHBondContact O-N 2.76Å; A197-M327 HydrophobicContact CB-SD 4.19Å
198	A	95.4	Very high	92.1	Very high	0 Å²	0	48.1 Å²	48.1	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-60.4	-45	176.4	0	0	0	0	0	112.4	I137 L138 A194 S195 I196 F201 G202	I137-A198 HydrophobicContact CB-CB 4.15Å; I137-A198 HydrophobicContact CG2-CB 4.15Å; L138-A198 HydrophobicContact CB-CB 4.44Å; A194-A198 WeakPolarHBondContact O-CB 3.35Å; A194-A198 PolarHBondContact O-N 3.35Å; S195-A198 PolarHBondContact O-N 2.92Å; I196-A198 VanDerWaalsContact C-N 3.33Å; I196-A198 PolarHBondContact O-N 3.43Å; A198-F201 PolarHBondContact O-N 3.45Å; A198-G202 PolarHBondContact O-N 3.29Å
199	V	94.7	Very high	91.7	Very high	24 Å²	24	53.9 Å²	53.9	15%	0.145	28%	0.282	C	S	.	.	H	α-helix	trans	-63.4	-43.9	176.7	171.3	0	0	0	0	111.7	S195 I196 A197 W203 F209 A214 L217	S195-V199 VanDerWaalsContact O-CG2 3.27Å; S195-V199 WeakPolarHBondContact O-CG2 3.37Å; S195-V199 PolarHBondContact O-N 3.39Å; I196-V199 PolarHBondContact O-N 2.91Å; A197-V199 PolarHBondContact O-N 3.21Å; V199-W203 VanDerWaalsContact O-CB 3.26Å; V199-W203 WeakPolarHBondContact O-CB 3.26Å; V199-W203 PolarHBondContact O-N 2.92Å; V199-F209 HydrophobicContact CG1-CD2 4.06Å; V199-F209 HydrophobicContact CG1-CE2 3.45Å; V199-F209 VanDerWaalsContact CG1-CE2 3.45Å; V199-F209 HydrophobicContact CG1-CZ 4.38Å; V199-A214 HydrophobicContact CG1-CB 4.24Å; V199-A214 HydrophobicContact CG2-CB 3.78Å; V199-L217 HydrophobicContact CG2-CD1 3.65Å
200	V	94.6	Very high	91.3	Very high	64 Å²	64	54 Å²	54	39%	0.388	28%	0.284	S	S	.	.	H	α-helix	trans	-66.3	-45.2	179.3	170.9	0	0	0	0	110.7	I196 A197 W203 I204	I196-V200 HydrophobicContact CG2-CG2 4.25Å; I196-V200 WeakPolarHBondContact O-CB 3.4Å; I196-V200 VanDerWaalsContact O-CG2 3.3Å; I196-V200 WeakPolarHBondContact O-CG2 3.32Å; I196-V200 PolarHBondContact O-N 3.2Å; A197-V200 PolarHBondContact O-N 3.2Å; V200-W203 PolarHBondContact O-N 2.85Å; V200-I204 HydrophobicContact CG1-CD1 3.97Å; V200-I204 VanDerWaalsContact O-CG1 3.31Å; V200-I204 WeakPolarHBondContact O-CG1 3.38Å; V200-I204 PolarHBondContact O-N 3.18Å; V200-I204 VanDerWaalsContact O-N 3.1Å
201	F	93.4	Very high	91.1	Very high	47 Å²	47	58.8 Å²	58.8	21%	0.206	31%	0.309	C	S	.	.	H	α-helix	trans	-72.4	-30	-179.6	-68.9	-20.4	0	0	0	113.4	I137 A197 A198 I204 P205 S331 V332 L335	I137-F201 HydrophobicContact CD1-CB 4.18Å; I137-F201 HydrophobicContact CG2-CB 4.19Å; I137-F201 HydrophobicContact CG2-CD2 4.28Å; A197-F201 VanDerWaalsContact O-CB 3.29Å; A197-F201 WeakPolarHBondContact O-CB 3.24Å; A197-F201 VanDerWaalsContact O-CG 3.31Å; A197-F201 WeakPolarHBondContact O-CG 3.4Å; A197-F201 PolarHBondContact O-N 2.76Å; A198-F201 PolarHBondContact O-N 3.45Å; F201-I204 HydrophobicContact CD1-CD1 4.17Å; F201-P205 WeakPolarHBondContact O-CD 3.46Å; F201-S331 VanDerWaalsContact CE2-CB 3.48Å; F201-V332 HydrophobicContact CE2-CG2 4.02Å; F201-V332 HydrophobicContact CZ-CG2 4.04Å; F201-L335 HydrophobicContact CB-CD1 4.29Å; F201-L335 HydrophobicContact CB-CD2 4.38Å; F201-L335 WeakPolarHBondContact O-CD1 3.45Å
202	G	90.7	Very high	90.8	Very high	2 Å²	2	61.9 Å²	61.9	2%	0.021	33%	0.328	C	S	.	.	H	α-helix	trans	-70.7	-36.2	169	0	0	0	0	0	112.4	A198 P205	A198-G202 PolarHBondContact O-N 3.29Å; G202-P205 WeakPolarHBondContact O-CD 3.33Å
203	W	91.8	Very high	90.6	Very high	132 Å²	132	60 Å²	60	50%	0.5	32%	0.321	S	S	.	.	H	α-helix	trans	-69.3	-35.4	179.1	176.1	60.3	0	0	0	113.7	V199 V200 G207	V199-W203 VanDerWaalsContact O-CB 3.26Å; V199-W203 WeakPolarHBondContact O-CB 3.26Å; V199-W203 PolarHBondContact O-N 2.92Å; V200-W203 PolarHBondContact O-N 2.85Å; W203-G207 PolarHBondContact NE1-O 2.88Å; W203-G207 VanDerWaalsContact O-CA 3.28Å; W203-G207 WeakPolarHBondContact O-CA 3.38Å; W203-G207 PolarHBondContact O-N 2.76Å
204	I	89.8	Confident	90.5	Very high	111 Å²	111	58.5 Å²	58.5	57%	0.569	32%	0.316	S	S	*	.	H	α-helix	trans	-60.4	-48.8	-175.1	-73.7	162.8	0	0	0	113	V200 F201	V200-I204 HydrophobicContact CG1-CD1 3.97Å; V200-I204 VanDerWaalsContact O-CG1 3.31Å; V200-I204 WeakPolarHBondContact O-CG1 3.38Å; V200-I204 PolarHBondContact O-N 3.18Å; V200-I204 VanDerWaalsContact O-N 3.1Å; F201-I204 HydrophobicContact CD1-CD1 4.17Å
205	P	85.2	Confident	90.4	Very high	65 Å²	65	63 Å²	63	42%	0.422	34%	0.336	S	S	.	.	H	α-helix	trans	-77.5	-40.7	179	-15.9	30	0	0	0	113.7	F201 G202 L335	F201-P205 WeakPolarHBondContact O-CD 3.46Å; G202-P205 WeakPolarHBondContact O-CD 3.33Å; P205-L335 HydrophobicContact CG-CD1 4.06Å
206	D	81.1	Confident	90.3	Very high	78 Å²	78	62.9 Å²	62.9	42%	0.417	34%	0.335	S	S	.	.	H	α-helix	trans	-97.5	-17.1	-167.4	-57.7	-50.5	0	0	0	113.1	H208 K339	D206-H208 PolarHBondContact O-CD2 3.03Å; D206-H208 PolarHBondContact O-N 2.92Å; D206-K339 IonicContact OD1-NZ 2.83Å; D206-K339 PolarHBondContact OD1-NZ 3.26Å; D206-K339 IonicContact OD2-NZ 2.77Å; D206-K339 PolarHBondContact OD2-NZ 3.28Å
207	G	83.3	Confident	90.3	Very high	49 Å²	49	59.3 Å²	59.3	51%	0.505	32%	0.316	S	S	.	.			trans	69.8	-6.4	175.8	0	0	0	0	0	115.5	W203	W203-G207 PolarHBondContact NE1-O 2.88Å; W203-G207 VanDerWaalsContact O-CA 3.28Å; W203-G207 WeakPolarHBondContact O-CA 3.38Å; W203-G207 PolarHBondContact O-N 2.76Å
208	H	81.1	Confident	90.4	Very high	158 Å²	158	59.1 Å²	59.1	73%	0.731	31%	0.314	S	S	*	.			trans	-93	117.1	-179.3	-73	-74.3	0	0	0	111.5	D206	D206-H208 PolarHBondContact O-CD2 3.03Å; D206-H208 PolarHBondContact O-N 2.92Å
209	F	85.8	Confident	90.4	Very high	124 Å²	124	59.1 Å²	59.1	54%	0.544	31%	0.314	S	S	.	.			trans	-102.7	106.7	175.7	-174	-96.1	0	0	0	110.7	V199 I211	V199-F209 HydrophobicContact CG1-CD2 4.06Å; V199-F209 HydrophobicContact CG1-CE2 3.45Å; V199-F209 VanDerWaalsContact CG1-CE2 3.45Å; V199-F209 HydrophobicContact CG1-CZ 4.38Å; F209-I211 HydrophobicContact CD1-CG1 4.21Å; F209-I211 HydrophobicContact CE1-CG1 3.78Å
210	S	87.8	Confident	90.5	Very high	40 Å²	40	58 Å²	58	28%	0.28	31%	0.307	S	S	.	.			trans	-101.1	109.2	177.5	-178.5	0	0	0	0	110.7	P212 H213 A214	S210-P212 VanDerWaalsContact C-N 3.35Å; S210-P212 WeakPolarHBondContact OG-CD 3.39Å; S210-H213 PolarHBondContact O-N 2.88Å; S210-H213 VanDerWaalsContact O-N 3.1Å; S210-H213 PolarHBondContact OG-CD2 3.23Å; S210-H213 VanDerWaalsContact OG-CD2 3.23Å; S210-A214 PolarHBondContact O-N 2.72Å
211	I	88.8	Confident	90.6	Very high	102 Å²	102	54.9 Å²	54.9	52%	0.523	29%	0.288	S	S	.	.	H	α-helix	trans	-55.7	-43.3	177	-64.5	171.3	0	0	0	112	F209 H213 A214 F215	F209-I211 HydrophobicContact CD1-CG1 4.21Å; F209-I211 HydrophobicContact CE1-CG1 3.78Å; I211-H213 VanDerWaalsContact C-N 3.34Å; I211-H213 PolarHBondContact O-N 3.45Å; I211-A214 PolarHBondContact O-N 2.95Å; I211-F215 HydrophobicContact CG2-CD2 3.65Å; I211-F215 HydrophobicContact CG2-CE2 3.54Å; I211-F215 WeakPolarHBondContact O-CD2 3.41Å; I211-F215 PolarHBondContact O-N 3.32Å; I211-F215 VanDerWaalsContact O-N 3.09Å
212	P	89.5	Confident	90.8	Very high	64 Å²	64	52.7 Å²	52.7	42%	0.416	28%	0.279	S	S	.	.	H	α-helix	trans	-58.6	-40.4	174.4	-26.4	35.5	0	0	0	113.8	S210 F215 L216	S210-P212 VanDerWaalsContact C-N 3.35Å; S210-P212 WeakPolarHBondContact OG-CD 3.39Å; P212-F215 PolarHBondContact O-N 3.42Å; P212-L216 WeakPolarHBondContact O-CB 3.41Å; P212-L216 PolarHBondContact O-N 3.49Å
213	H	90.9	Very high	91.1	Very high	48 Å²	48	52.8 Å²	52.8	22%	0.222	28%	0.279	C	S	.	.	H	α-helix	trans	-65.1	-44.2	177.4	-66.4	-165.8	0	0	0	110.2	K131 V132 E134 S210 I211 F215 L216 L217	K131-H213 PolarHBondContact O-CE1 2.85Å; K131-H213 VanDerWaalsContact O-CE1 3.26Å; V132-H213 HydrophobicContact CG1-CB 4.02Å; E134-H213 IonicContact OE1-ND1 3.63Å; E134-H213 IonicContact OE2-ND1 3.57Å; S210-H213 PolarHBondContact O-N 2.88Å; S210-H213 VanDerWaalsContact O-N 3.1Å; S210-H213 PolarHBondContact OG-CD2 3.23Å; S210-H213 VanDerWaalsContact OG-CD2 3.23Å; I211-H213 VanDerWaalsContact C-N 3.34Å; I211-H213 PolarHBondContact O-N 3.45Å; H213-F215 VanDerWaalsContact C-N 3.33Å; H213-F215 PolarHBondContact O-N 2.96Å; H213-L216 PolarHBondContact O-N 3.44Å; H213-L216 VanDerWaalsContact O-N 3.15Å; H213-L217 WeakPolarHBondContact O-CB 3.32Å; H213-L217 WeakPolarHBondContact O-CD1 3.4Å; H213-L217 WeakPolarHBondContact O-CG 3.48Å; H213-L217 PolarHBondContact O-N 3.21Å
214	A	93.2	Very high	91.3	Very high	22 Å²	22	46.5 Å²	46.5	18%	0.182	26%	0.255	C	S	.	.	H	α-helix	trans	-58.3	-43.6	178	0	0	0	0	0	112.6	V199 S210 I211 C218	V199-A214 HydrophobicContact CG1-CB 4.24Å; V199-A214 HydrophobicContact CG2-CB 3.78Å; S210-A214 PolarHBondContact O-N 2.72Å; I211-A214 PolarHBondContact O-N 2.95Å; A214-C218 VanDerWaalsContact O-CB 3.29Å; A214-C218 WeakPolarHBondContact O-CB 3.32Å; A214-C218 PolarHBondContact O-N 3.39Å
215	F	93.9	Very high	91.6	Very high	95 Å²	95	41.5 Å²	41.5	42%	0.417	23%	0.231	S	C	.	.	H	α-helix	trans	-69.1	-38.2	175.6	-81.3	-65.7	0	0	0	113	I211 P212 H213 C218 A219 Y288 P289	I211-F215 HydrophobicContact CG2-CD2 3.65Å; I211-F215 HydrophobicContact CG2-CE2 3.54Å; I211-F215 WeakPolarHBondContact O-CD2 3.41Å; I211-F215 PolarHBondContact O-N 3.32Å; I211-F215 VanDerWaalsContact O-N 3.09Å; P212-F215 PolarHBondContact O-N 3.42Å; H213-F215 VanDerWaalsContact C-N 3.33Å; H213-F215 PolarHBondContact O-N 2.96Å; F215-C218 PolarHBondContact O-N 3.33Å; F215-A219 VanDerWaalsContact O-CB 3.29Å; F215-A219 WeakPolarHBondContact O-CB 3.22Å; F215-A219 PolarHBondContact O-N 3.35Å; F215-Y288 HydrophobicContact CB-CD2 3.84Å; F215-Y288 HydrophobicContact CB-CG 4.23Å; F215-P289 HydrophobicContact CD1-CB 4.45Å; F215-P289 HydrophobicContact CE1-CB 4.37Å
216	L	95	Very high	92.1	Very high	2 Å²	2	39.1 Å²	39.1	1%	0.01	21%	0.214	C	C	.	.	H	α-helix	trans	-62.6	-47.6	174.9	174.6	63.2	0	0	0	111.4	V128 V132 P212 H213 C218 A219 S220 L277 Y278 Y288	V128-L216 HydrophobicContact CG2-CD2 4.08Å; V132-L216 HydrophobicContact CG1-CD2 4.43Å; V132-L216 HydrophobicContact CG2-CD2 4.01Å; P212-L216 WeakPolarHBondContact O-CB 3.41Å; P212-L216 PolarHBondContact O-N 3.49Å; H213-L216 PolarHBondContact O-N 3.44Å; H213-L216 VanDerWaalsContact O-N 3.15Å; L216-C218 VanDerWaalsContact C-N 3.34Å; L216-C218 PolarHBondContact O-N 2.9Å; L216-A219 PolarHBondContact O-N 3.12Å; L216-S220 VanDerWaalsContact O-CB 3.28Å; L216-S220 WeakPolarHBondContact O-CB 3.26Å; L216-S220 PolarHBondContact O-N 3.19Å; L216-S220 PolarHBondContact O-OG 2.86Å; L216-L277 HydrophobicContact CD1-CB 3.6Å; L216-L277 HydrophobicContact CD1-CD1 4.37Å; L216-Y278 HydrophobicContact CD2-CD2 4.09Å; L216-Y288 HydrophobicContact CB-CD2 4.19Å; L216-Y288 HydrophobicContact CB-CE1 4.41Å; L216-Y288 HydrophobicContact CB-CE2 3.81Å; L216-Y288 HydrophobicContact CD1-CD1 4.35Å; L216-Y288 HydrophobicContact CD1-CE1 3.75Å
217	L	95.7	Very high	92.8	Very high	1 Å²	1	38.1 Å²	38.1	1%	0.005	21%	0.208	C	C	.	.	H	α-helix	trans	-62	-42.1	177.9	-68	164.4	0	0	0	111	V132 E134 V135 V199 H213 S220 S221	V132-L217 HydrophobicContact CG1-CD2 4.19Å; V132-L217 HydrophobicContact CG1-CG 4.31Å; E134-L217 HydrophobicContact CB-CD1 3.56Å; E134-L217 HydrophobicContact CB-CD2 4.02Å; E134-L217 HydrophobicContact CB-CG 4.41Å; E134-L217 HydrophobicContact CG-CD1 4.25Å; V135-L217 HydrophobicContact CB-CD2 4.48Å; V135-L217 HydrophobicContact CG2-CD2 3.75Å; V199-L217 HydrophobicContact CG2-CD1 3.65Å; H213-L217 WeakPolarHBondContact O-CB 3.32Å; H213-L217 WeakPolarHBondContact O-CD1 3.4Å; H213-L217 WeakPolarHBondContact O-CG 3.48Å; H213-L217 PolarHBondContact O-N 3.21Å; L217-S220 WeakPolarHBondContact CA-OG 3.17Å; L217-S220 PolarHBondContact O-OG 3.42Å; L217-S221 WeakPolarHBondContact O-CB 3.04Å; L217-S221 PolarHBondContact O-N 3.25Å
218	C	96.3	Very high	93.3	Very high	13 Å²	13	35.9 Å²	35.9	9%	0.088	19%	0.185	C	C	.	.	H	α-helix	trans	-62.8	-49.1	175.2	-177.5	0	0	0	0	111.8	F192 S195 A214 F215 L216 V222 C292	F192-C218 VanDerWaalsContact CD2-SG 3.57Å; S195-C218 WeakPolarHBondContact OG-CA 3.22Å; A214-C218 VanDerWaalsContact O-CB 3.29Å; A214-C218 WeakPolarHBondContact O-CB 3.32Å; A214-C218 PolarHBondContact O-N 3.39Å; F215-C218 PolarHBondContact O-N 3.33Å; L216-C218 VanDerWaalsContact C-N 3.34Å; L216-C218 PolarHBondContact O-N 2.9Å; C218-V222 WeakPolarHBondContact O-CB 3.1Å; C218-V222 VanDerWaalsContact O-CG2 3.27Å; C218-V222 WeakPolarHBondContact O-CG2 3.47Å; C218-V222 PolarHBondContact O-N 3.45Å; C218-C292 PolarHBondContact SG-SG 3.33Å
219	A	96.3	Very high	93.9	Very high	0 Å²	0	28.7 Å²	28.7	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-64.9	-47	-178.4	0	0	0	0	0	111.8	F215 L216 A223 L277 V291 C292	F215-A219 VanDerWaalsContact O-CB 3.29Å; F215-A219 WeakPolarHBondContact O-CB 3.22Å; F215-A219 PolarHBondContact O-N 3.35Å; L216-A219 PolarHBondContact O-N 3.12Å; A219-A223 WeakPolarHBondContact O-CB 3.33Å; A219-A223 PolarHBondContact O-N 3.46Å; A219-L277 HydrophobicContact CB-CD1 3.74Å; A219-V291 HydrophobicContact CB-CB 4.18Å; A219-V291 HydrophobicContact CB-CG1 4.1Å; A219-C292 WeakPolarHBondContact CA-SG 3.33Å; A219-C292 PolarHBondContact N-SG 3Å; A219-C292 VanDerWaalsContact N-SG 3.37Å
220	S	96.9	Very high	94.3	Very high	0 Å²	0	25.6 Å²	25.6	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-64.6	-46.9	177.8	56.1	0	0	0	0	111.8	L216 L217 T224 S274	L216-S220 VanDerWaalsContact O-CB 3.28Å; L216-S220 WeakPolarHBondContact O-CB 3.26Å; L216-S220 PolarHBondContact O-N 3.19Å; L216-S220 PolarHBondContact O-OG 2.86Å; L217-S220 WeakPolarHBondContact CA-OG 3.17Å; L217-S220 PolarHBondContact O-OG 3.42Å; S220-T224 WeakPolarHBondContact O-CB 3.41Å; S220-T224 PolarHBondContact O-N 3.25Å; S220-T224 PolarHBondContact O-OG1 3.13Å; S220-S274 VanDerWaalsContact CB-OG 3.24Å; S220-S274 WeakPolarHBondContact CB-OG 3.39Å
221	S	96.9	Very high	94.6	Very high	0 Å²	0	26.6 Å²	26.6	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-61	-53	179.3	-176.4	0	0	0	0	112.5	L138 G191 L217 A223 T224 A225	L138-S221 WeakPolarHBondContact CD1-OG 3.24Å; G191-S221 VanDerWaalsContact C-OG 3.27Å; G191-S221 WeakPolarHBondContact CA-OG 3.5Å; G191-S221 WeakPolarHBondContact O-CB 3.42Å; G191-S221 PolarHBondContact O-OG 2.84Å; L217-S221 WeakPolarHBondContact O-CB 3.04Å; L217-S221 PolarHBondContact O-N 3.25Å; S221-A223 PolarHBondContact O-N 3.34Å; S221-T224 PolarHBondContact O-N 3.2Å; S221-A225 VanDerWaalsContact O-CB 3.29Å; S221-A225 WeakPolarHBondContact O-CB 3.43Å; S221-A225 PolarHBondContact O-N 2.99Å
222	V	96.7	Very high	94.8	Very high	1 Å²	1	21.9 Å²	21.9	1%	0.006	12%	0.121	C	C	.	.	H	α-helix	trans	-64.5	-44.9	-177	174.3	0	0	0	0	110.6	T188 F192 C218 F226 F295	T188-V222 HydrophobicContact CG2-CG1 3.93Å; F192-V222 HydrophobicContact CB-CG2 3.83Å; F192-V222 HydrophobicContact CD2-CG2 4.49Å; C218-V222 WeakPolarHBondContact O-CB 3.1Å; C218-V222 VanDerWaalsContact O-CG2 3.27Å; C218-V222 WeakPolarHBondContact O-CG2 3.47Å; C218-V222 PolarHBondContact O-N 3.45Å; V222-F226 WeakPolarHBondContact O-CB 3.49Å; V222-F226 PolarHBondContact O-N 2.96Å; V222-F295 HydrophobicContact CG1-CB 3.48Å; V222-F295 VanDerWaalsContact CG1-CB 3.48Å; V222-F295 HydrophobicContact CG1-CD2 4.36Å; V222-F295 HydrophobicContact CG1-CG 4.06Å
223	A	96.9	Very high	94.9	Very high	3 Å²	3	18.8 Å²	18.8	3%	0.025	10%	0.101	C	C	.	.	H	α-helix	trans	-63.3	-43.7	177.6	0	0	0	0	0	111.8	A219 S221 I227 I273 V291 F295	A219-A223 WeakPolarHBondContact O-CB 3.33Å; A219-A223 PolarHBondContact O-N 3.46Å; S221-A223 PolarHBondContact O-N 3.34Å; A223-I227 WeakPolarHBondContact O-CB 3.04Å; A223-I227 WeakPolarHBondContact O-CD1 3.28Å; A223-I227 WeakPolarHBondContact O-CG1 3.2Å; A223-I227 PolarHBondContact O-N 3.21Å; A223-I273 HydrophobicContact CB-CD1 4.2Å; A223-I273 HydrophobicContact CB-CG2 4.08Å; A223-V291 HydrophobicContact CB-CG1 4.17Å; A223-F295 HydrophobicContact CB-CD2 4.01Å; A223-F295 HydrophobicContact CB-CE2 3.35Å; A223-F295 HydrophobicContact CB-CZ 3.89Å
224	T	96.7	Very high	94.9	Very high	0 Å²	0	21.6 Å²	21.6	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-63.5	-53.2	178.3	-60.3	0	0	0	0	110.9	L142 S220 S221 F226 I227 A228 T266 L269 L270	L142-T224 HydrophobicContact CD1-CG2 4.02Å; S220-T224 WeakPolarHBondContact O-CB 3.41Å; S220-T224 PolarHBondContact O-N 3.25Å; S220-T224 PolarHBondContact O-OG1 3.13Å; S221-T224 PolarHBondContact O-N 3.2Å; T224-F226 VanDerWaalsContact C-N 3.28Å; T224-F226 PolarHBondContact O-N 3.36Å; T224-I227 PolarHBondContact O-N 3.45Å; T224-A228 WeakPolarHBondContact O-CA 3.37Å; T224-A228 WeakPolarHBondContact O-CB 3.19Å; T224-A228 PolarHBondContact O-N 2.85Å; T224-T266 HydrophobicContact CG2-CG2 4.24Å; T224-T266 WeakPolarHBondContact CG2-O 3.46Å; T224-L269 HydrophobicContact CG2-CB 4.03Å; T224-L270 HydrophobicContact CG2-CB 3.87Å; T224-L270 WeakPolarHBondContact OG1-CA 3.2Å
225	A	95.5	Very high	94.9	Very high	7 Å²	7	23.1 Å²	23.1	6%	0.058	12%	0.12	C	C	.	.	H	α-helix	trans	-57.8	-43.6	-179.5	0	0	0	0	0	111.1	L142 L145 A187 S221 S229	L142-A225 HydrophobicContact CD2-CB 4.09Å; L145-A225 HydrophobicContact CD2-CB 4.2Å; A187-A225 HydrophobicContact CB-CB 4.23Å; A187-A225 WeakPolarHBondContact CB-O 3.5Å; A187-A225 VanDerWaalsContact O-CB 3.27Å; A187-A225 WeakPolarHBondContact O-CB 3.43Å; S221-A225 VanDerWaalsContact O-CB 3.29Å; S221-A225 WeakPolarHBondContact O-CB 3.43Å; S221-A225 PolarHBondContact O-N 2.99Å; A225-S229 WeakPolarHBondContact O-CB 3.39Å; A225-S229 PolarHBondContact O-N 2.92Å; A225-S229 PolarHBondContact O-OG 3.07Å
226	F	95.2	Very high	94.7	Very high	15 Å²	15	18.7 Å²	18.7	7%	0.066	10%	0.101	C	C	.	.	H	α-helix	trans	-62.6	-55.7	176.6	-172.5	-78.6	0	0	0	112.2	Q184 T188 V222 T224 S229 L230 F295 L298 W302	Q184-F226 HydrophobicContact CB-CE2 4.39Å; Q184-F226 VanDerWaalsContact OE1-CG 3.3Å; Q184-F226 PolarHBondContact OE1-O 3.12Å; T188-F226 WeakPolarHBondContact OG1-CD2 3.49Å; V222-F226 WeakPolarHBondContact O-CB 3.49Å; V222-F226 PolarHBondContact O-N 2.96Å; T224-F226 VanDerWaalsContact C-N 3.28Å; T224-F226 PolarHBondContact O-N 3.36Å; F226-S229 PolarHBondContact O-N 3Å; F226-S229 PolarHBondContact O-OG 2.77Å; F226-L230 HydrophobicContact CE1-CD2 4.19Å; F226-L230 VanDerWaalsContact O-CB 3.31Å; F226-L230 WeakPolarHBondContact O-CB 3.45Å; F226-L230 PolarHBondContact O-N 3.42Å; F226-F295 HydrophobicContact CB-CD1 3.79Å; F226-F295 HydrophobicContact CB-CE1 3.86Å; F226-F295 AromaticContact CD1-CD1 3.75Å; F226-F295 HydrophobicContact CD1-CD1 3.75Å; F226-F295 AromaticContact CD1-CE1 3.39Å; F226-F295 HydrophobicContact CD1-CE1 3.39Å; F226-F295 AromaticContact CD2-CD1 3.67Å; F226-F295 HydrophobicContact CD2-CD1 3.67Å; F226-F295 HydrophobicContact CD2-CE1 4.21Å; F226-F295 HydrophobicContact CE1-CD1 4.23Å; F226-F295 AromaticContact CE1-CE1 3.95Å; F226-F295 HydrophobicContact CE1-CE1 3.95Å; F226-F295 HydrophobicContact CE2-CD1 4.16Å; F226-F295 AromaticContact CG-CD1 3.45Å; F226-F295 HydrophobicContact CG-CD1 3.45Å; F226-F295 VanDerWaalsContact CG-CD1 3.45Å; F226-F295 AromaticContact CG-CE1 3.55Å; F226-F295 HydrophobicContact CG-CE1 3.55Å; F226-F295 HydrophobicContact CZ-CD1 4.42Å; F226-L298 HydrophobicContact CE2-CD1 4.06Å; F226-L298 HydrophobicContact CZ-CD1 3.77Å; F226-W302 AromaticContact CE2-NE1 3.35Å; F226-W302 HydrophobicContact CZ-CZ2 4.01Å; F226-W302 AromaticContact CZ-NE1 3.54Å
227	I	95.7	Very high	94.4	Very high	57 Å²	57	19.1 Å²	19.1	29%	0.292	10%	0.103	S	C	.	.	H	α-helix	trans	-67.4	-43.7	-174.8	-64.1	167.1	0	0	0	110.5	A223 T224 L230 V231 L269 I273 F295	A223-I227 WeakPolarHBondContact O-CB 3.04Å; A223-I227 WeakPolarHBondContact O-CD1 3.28Å; A223-I227 WeakPolarHBondContact O-CG1 3.2Å; A223-I227 PolarHBondContact O-N 3.21Å; T224-I227 PolarHBondContact O-N 3.45Å; I227-L230 PolarHBondContact O-N 3.4Å; I227-V231 HydrophobicContact CG2-CG2 4.22Å; I227-V231 WeakPolarHBondContact O-CB 3.21Å; I227-V231 VanDerWaalsContact O-CG2 3.27Å; I227-V231 WeakPolarHBondContact O-CG2 3.41Å; I227-V231 PolarHBondContact O-N 3Å; I227-L269 HydrophobicContact CB-CD1 4.24Å; I227-L269 HydrophobicContact CG2-CD1 3.77Å; I227-L269 HydrophobicContact CG2-CD2 4.02Å; I227-I273 HydrophobicContact CD1-CD1 3.97Å; I227-F295 HydrophobicContact CD1-CZ 4.23Å; I227-F295 HydrophobicContact CG1-CZ 4.33Å
228	A	94.7	Very high	94.1	Very high	2 Å²	2	21 Å²	21	2%	0.017	12%	0.123	C	C	.	.	H	α-helix	trans	-60.1	-49.6	178.2	0	0	0	0	0	110.7	T224 L230 V231 L232 T266 L269	T224-A228 WeakPolarHBondContact O-CA 3.37Å; T224-A228 WeakPolarHBondContact O-CB 3.19Å; T224-A228 PolarHBondContact O-N 2.85Å; A228-L230 VanDerWaalsContact C-N 3.32Å; A228-L230 PolarHBondContact O-N 3.1Å; A228-V231 PolarHBondContact O-N 3.48Å; A228-L232 HydrophobicContact CB-CD1 4.48Å; A228-L232 WeakPolarHBondContact O-CB 3.37Å; A228-L232 WeakPolarHBondContact O-CD1 3.36Å; A228-L232 WeakPolarHBondContact O-CG 3.16Å; A228-L232 PolarHBondContact O-N 3.4Å; A228-T266 HydrophobicContact CB-CG2 4.49Å; A228-L269 HydrophobicContact CB-CD1 3.79Å
229	S	93.6	Very high	93.8	Very high	6 Å²	6	21.7 Å²	21.7	4%	0.042	13%	0.126	C	C	.	.	H	α-helix	trans	-67.5	-31	179.5	67	0	0	0	0	113.4	E150 Q184 A187 A225 F226 G233	E150-S229 VanDerWaalsContact OE1-CA 3.29Å; E150-S229 WeakPolarHBondContact OE1-CA 3.45Å; E150-S229 WeakPolarHBondContact OE1-CB 3.5Å; Q184-S229 PolarHBondContact NE2-OG 2.79Å; Q184-S229 VanDerWaalsContact NE2-OG 3.1Å; A187-S229 VanDerWaalsContact CB-OG 3.26Å; A187-S229 WeakPolarHBondContact CB-OG 3.32Å; A225-S229 WeakPolarHBondContact O-CB 3.39Å; A225-S229 PolarHBondContact O-N 2.92Å; A225-S229 PolarHBondContact O-OG 3.07Å; F226-S229 PolarHBondContact O-N 3Å; F226-S229 PolarHBondContact O-OG 2.77Å; S229-G233 WeakPolarHBondContact O-CA 3.43Å; S229-G233 PolarHBondContact O-N 3.2Å
230	L	94	Very high	93.3	Very high	60 Å²	60	21.7 Å²	21.7	31%	0.314	13%	0.127	S	C	.	.	H	α-helix	trans	-68.1	-49.2	174.2	-176	63.3	0	0	0	110.8	M180 F226 I227 A228 M234	M180-L230 HydrophobicContact CG-CD1 4.38Å; M180-L230 HydrophobicContact SD-CD1 3.8Å; F226-L230 HydrophobicContact CE1-CD2 4.19Å; F226-L230 VanDerWaalsContact O-CB 3.31Å; F226-L230 WeakPolarHBondContact O-CB 3.45Å; F226-L230 PolarHBondContact O-N 3.42Å; I227-L230 PolarHBondContact O-N 3.4Å; A228-L230 VanDerWaalsContact C-N 3.32Å; A228-L230 PolarHBondContact O-N 3.1Å; L230-M234 WeakPolarHBondContact O-CB 3.39Å; L230-M234 WeakPolarHBondContact O-CG 3.39Å; L230-M234 PolarHBondContact O-N 3.16Å
231	V	94.2	Very high	92.8	Very high	61 Å²	61	23.9 Å²	23.9	37%	0.37	14%	0.138	S	C	.	.	H	α-helix	trans	-64.6	-50	-179.6	170.7	0	0	0	0	110.4	I227 A228 M234 I235 I265	I227-V231 HydrophobicContact CG2-CG2 4.22Å; I227-V231 WeakPolarHBondContact O-CB 3.21Å; I227-V231 VanDerWaalsContact O-CG2 3.27Å; I227-V231 WeakPolarHBondContact O-CG2 3.41Å; I227-V231 PolarHBondContact O-N 3Å; A228-V231 PolarHBondContact O-N 3.48Å; V231-M234 PolarHBondContact O-N 2.63Å; V231-I235 HydrophobicContact CG1-CD1 3.84Å; V231-I235 VanDerWaalsContact O-CG1 3.3Å; V231-I235 WeakPolarHBondContact O-CG1 3.27Å; V231-I235 PolarHBondContact O-N 3.17Å; V231-I265 HydrophobicContact CG1-CD1 4.2Å; V231-I265 HydrophobicContact CG1-CG2 4.42Å
232	L	92.4	Very high	92.3	Very high	2 Å²	2	25.2 Å²	25.2	1%	0.01	15%	0.151	C	C	.	.	H	α-helix	trans	-64	-47.3	179.5	-70.2	167.6	0	0	0	111.1	E150 A228 M234 I235 M236 L261 I265	E150-L232 HydrophobicContact CG-CB 4.09Å; E150-L232 HydrophobicContact CG-CD1 4.26Å; A228-L232 HydrophobicContact CB-CD1 4.48Å; A228-L232 WeakPolarHBondContact O-CB 3.37Å; A228-L232 WeakPolarHBondContact O-CD1 3.36Å; A228-L232 WeakPolarHBondContact O-CG 3.16Å; A228-L232 PolarHBondContact O-N 3.4Å; L232-M234 VanDerWaalsContact C-N 3.25Å; L232-M234 PolarHBondContact O-N 3.05Å; L232-I235 CarbonylContact O-C 3.28Å; L232-I235 WeakPolarHBondContact O-CB 3.36Å; L232-I235 PolarHBondContact O-N 3.49Å; L232-I235 VanDerWaalsContact O-N 3.1Å; L232-M236 WeakPolarHBondContact O-CB 3.4Å; L232-M236 VanDerWaalsContact O-CG 3.25Å; L232-M236 WeakPolarHBondContact O-CG 3.46Å; L232-M236 PolarHBondContact O-N 2.81Å; L232-L261 HydrophobicContact CD2-CB 4.08Å; L232-I265 HydrophobicContact CD2-CB 4.33Å; L232-I265 HydrophobicContact CD2-CD1 3.79Å; L232-I265 HydrophobicContact CG-CG2 4.41Å
233	G	91.7	Very high	91.8	Very high	0 Å²	0	25.6 Å²	25.6	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-56.2	-41.2	176.7	0	0	0	0	0	112.3	E150 S229 M236 I237	E150-G233 PolarHBondContact OE2-N 3.37Å; S229-G233 WeakPolarHBondContact O-CA 3.43Å; S229-G233 PolarHBondContact O-N 3.2Å; G233-M236 PolarHBondContact O-N 3.35Å; G233-I237 WeakPolarHBondContact O-CB 3.28Å; G233-I237 VanDerWaalsContact O-CD1 3.27Å; G233-I237 WeakPolarHBondContact O-CD1 3.41Å; G233-I237 WeakPolarHBondContact O-CG1 3.31Å; G233-I237 PolarHBondContact O-N 3.45Å
234	M	92.2	Very high	90.9	Very high	107 Å²	107	29.7 Å²	29.7	53%	0.527	17%	0.169	S	C	.	.	H	α-helix	trans	-67.6	-41.5	177.5	-73.3	-59.5	-61.6	0	0	112.2	M180 L230 V231 L232 M236 G238	M180-M234 HydrophobicContact CE-CG 3.84Å; M180-M234 HydrophobicContact CE-SD 3.78Å; L230-M234 WeakPolarHBondContact O-CB 3.39Å; L230-M234 WeakPolarHBondContact O-CG 3.39Å; L230-M234 PolarHBondContact O-N 3.16Å; V231-M234 PolarHBondContact O-N 2.63Å; L232-M234 VanDerWaalsContact C-N 3.25Å; L232-M234 PolarHBondContact O-N 3.05Å; M234-M236 VanDerWaalsContact C-N 3.34Å; M234-G238 PolarHBondContact O-N 3.43Å
235	I	92.1	Very high	90.3	Very high	54 Å²	54	38 Å²	38	28%	0.277	21%	0.205	S	C	.	.	H	α-helix	trans	-60.6	-46.8	173.2	-68.6	166	0	0	0	109.6	V231 L232 I237 G238 V239 I257 L261 I265	V231-I235 HydrophobicContact CG1-CD1 3.84Å; V231-I235 VanDerWaalsContact O-CG1 3.3Å; V231-I235 WeakPolarHBondContact O-CG1 3.27Å; V231-I235 PolarHBondContact O-N 3.17Å; L232-I235 CarbonylContact O-C 3.28Å; L232-I235 WeakPolarHBondContact O-CB 3.36Å; L232-I235 PolarHBondContact O-N 3.49Å; L232-I235 VanDerWaalsContact O-N 3.1Å; I235-I237 PolarHBondContact O-N 3.49Å; I235-G238 CarbonylContact O-C 3.56Å; I235-G238 WeakPolarHBondContact O-CA 3.44Å; I235-G238 PolarHBondContact O-N 2.99Å; I235-G238 VanDerWaalsContact O-N 3.09Å; I235-V239 HydrophobicContact CG2-CG2 4.22Å; I235-V239 WeakPolarHBondContact O-CG2 3.46Å; I235-V239 PolarHBondContact O-N 3.41Å; I235-I257 HydrophobicContact CG2-CG2 4.37Å; I235-L261 HydrophobicContact CD1-CD1 4.36Å; I235-L261 HydrophobicContact CG2-CD1 3.96Å; I235-I265 HydrophobicContact CD1-CD1 3.94Å
236	M	90	Very high	89.8	Confident	1 Å²	1	43.9 Å²	43.9	1%	0.005	23%	0.234	C	C	.	.	H	α-helix	trans	-62.4	-45.2	-178.2	-69.5	-34.3	-57.2	0	0	112.5	L153 A154 L232 G233 M234 G238 V239 I240 A254 I257 A258	L153-M236 HydrophobicContact CD2-CB 4.21Å; A154-M236 HydrophobicContact CB-CE 4.3Å; L232-M236 WeakPolarHBondContact O-CB 3.4Å; L232-M236 VanDerWaalsContact O-CG 3.25Å; L232-M236 WeakPolarHBondContact O-CG 3.46Å; L232-M236 PolarHBondContact O-N 2.81Å; G233-M236 PolarHBondContact O-N 3.35Å; M234-M236 VanDerWaalsContact C-N 3.34Å; M236-G238 VanDerWaalsContact C-N 3.29Å; M236-G238 PolarHBondContact O-N 3.15Å; M236-V239 PolarHBondContact O-N 3.49Å; M236-I240 VanDerWaalsContact O-CG1 3.24Å; M236-I240 WeakPolarHBondContact O-CG1 3.19Å; M236-I240 PolarHBondContact O-N 2.91Å; M236-A254 HydrophobicContact CE-CB 3.46Å; M236-A254 VanDerWaalsContact CE-CB 3.46Å; M236-A254 WeakPolarHBondContact CE-O 3.49Å; M236-I257 HydrophobicContact SD-CG2 4.38Å; M236-A258 HydrophobicContact CE-CB 3.84Å; M236-A258 HydrophobicContact CG-CB 4.19Å; M236-A258 VanDerWaalsContact SD-CA 3.57Å; M236-A258 HydrophobicContact SD-CB 3.54Å; M236-A258 VanDerWaalsContact SD-CB 3.54Å
237	I	88.8	Confident	88.9	Confident	11 Å²	11	46.5 Å²	46.5	6%	0.056	27%	0.266	C	S	.	.	H	α-helix	trans	-58.2	-44.7	172.9	-69.9	157.8	0	0	0	110.6	L157 I176 M180 G233 I235 I240 I241	L157-I237 HydrophobicContact CD1-CG1 3.67Å; I176-I237 HydrophobicContact CB-CD1 4.41Å; I176-I237 HydrophobicContact CD1-CG2 3.62Å; I176-I237 HydrophobicContact CG1-CD1 4.38Å; I176-I237 HydrophobicContact CG1-CG1 4.31Å; I176-I237 HydrophobicContact CG1-CG2 3.81Å; I176-I237 HydrophobicContact CG2-CD1 3.61Å; I176-I237 HydrophobicContact CG2-CG1 4.42Å; I176-I237 HydrophobicContact CG2-CG2 4.34Å; M180-I237 HydrophobicContact CE-CD1 3.64Å; G233-I237 WeakPolarHBondContact O-CB 3.28Å; G233-I237 VanDerWaalsContact O-CD1 3.27Å; G233-I237 WeakPolarHBondContact O-CD1 3.41Å; G233-I237 WeakPolarHBondContact O-CG1 3.31Å; G233-I237 PolarHBondContact O-N 3.45Å; I235-I237 PolarHBondContact O-N 3.49Å; I237-I240 PolarHBondContact O-N 3.48Å; I237-I241 HydrophobicContact CG2-CD1 3.65Å; I237-I241 HydrophobicContact CG2-CG1 4.42Å; I237-I241 WeakPolarHBondContact O-CB 3.39Å; I237-I241 VanDerWaalsContact O-CG1 3.28Å; I237-I241 WeakPolarHBondContact O-CG1 3.43Å; I237-I241 PolarHBondContact O-N 3.05Å
238	G	90.2	Very high	87.8	Confident	42 Å²	42	47.6 Å²	47.6	43%	0.433	27%	0.271	S	S	.	.	H	α-helix	trans	-59.8	-45	176.6	0	0	0	0	0	112.9	M234 I235 M236 G242	M234-G238 PolarHBondContact O-N 3.43Å; I235-G238 CarbonylContact O-C 3.56Å; I235-G238 WeakPolarHBondContact O-CA 3.44Å; I235-G238 PolarHBondContact O-N 2.99Å; I235-G238 VanDerWaalsContact O-N 3.09Å; M236-G238 VanDerWaalsContact C-N 3.29Å; M236-G238 PolarHBondContact O-N 3.15Å; G238-G242 PolarHBondContact O-N 2.95Å
239	V	89.1	Confident	86.7	Confident	26 Å²	26	50.1 Å²	50.1	16%	0.158	29%	0.285	C	S	.	.	H	α-helix	trans	-62.5	-44.3	176.9	169.8	0	0	0	0	111.1	I235 M236 G242 S243 V253 A254 I257	I235-V239 HydrophobicContact CG2-CG2 4.22Å; I235-V239 WeakPolarHBondContact O-CG2 3.46Å; I235-V239 PolarHBondContact O-N 3.41Å; M236-V239 PolarHBondContact O-N 3.49Å; V239-G242 PolarHBondContact O-N 2.77Å; V239-S243 VanDerWaalsContact O-CB 3.27Å; V239-S243 WeakPolarHBondContact O-CB 3.4Å; V239-S243 PolarHBondContact O-N 3.36Å; V239-S243 PolarHBondContact O-OG 3.03Å; V239-V253 HydrophobicContact CG1-CB 4.36Å; V239-V253 HydrophobicContact CG1-CG1 3.83Å; V239-A254 HydrophobicContact CG1-CB 4.22Å; V239-I257 HydrophobicContact CG1-CD1 4.02Å; V239-I257 HydrophobicContact CG2-CD1 3.95Å; V239-I257 HydrophobicContact CG2-CG2 4.17Å
240	I	85.8	Confident	85.7	Confident	1 Å²	1	50 Å²	50	1%	0.005	28%	0.284	C	S	.	.	H	α-helix	trans	-66.9	-47.8	-178.4	-67.9	168.1	0	0	0	110.8	L157 A161 M166 M236 I237 G242 S243 R244 P250 A254	L157-I240 HydrophobicContact CB-CD1 3.53Å; L157-I240 HydrophobicContact CB-CG2 4.48Å; L157-I240 HydrophobicContact CD1-CD1 4.14Å; L157-I240 HydrophobicContact CG-CD1 4.49Å; A161-I240 HydrophobicContact CB-CG2 4.17Å; M166-I240 HydrophobicContact CE-CG2 4.31Å; M236-I240 VanDerWaalsContact O-CG1 3.24Å; M236-I240 WeakPolarHBondContact O-CG1 3.19Å; M236-I240 PolarHBondContact O-N 2.91Å; I237-I240 PolarHBondContact O-N 3.48Å; I240-G242 VanDerWaalsContact C-N 3.33Å; I240-G242 PolarHBondContact O-N 3.34Å; I240-S243 PolarHBondContact O-N 3.39Å; I240-R244 WeakPolarHBondContact O-CB 3.36Å; I240-R244 PolarHBondContact O-N 3.11Å; I240-R244 VanDerWaalsContact O-N 3.08Å; I240-P250 HydrophobicContact CB-CB 4.28Å; I240-P250 HydrophobicContact CG1-CB 4.16Å; I240-P250 HydrophobicContact CG2-CB 3.98Å; I240-P250 HydrophobicContact CG2-CG 4.45Å; I240-A254 HydrophobicContact CD1-CB 4.33Å; I240-A254 HydrophobicContact CG1-CB 3.81Å
241	I	86.8	Confident	84.5	Confident	46 Å²	46	49.7 Å²	49.7	24%	0.236	28%	0.282	C	S	.	.	H	α-helix	trans	-64.1	-40.7	177	-63.9	169.2	0	0	0	110.7	L172 I176 I237 K245	L172-I241 HydrophobicContact CD1-CD1 4.32Å; L172-I241 HydrophobicContact CD1-CG1 4.38Å; L172-I241 HydrophobicContact CD2-CD1 4.36Å; I176-I241 HydrophobicContact CD1-CD1 3.95Å; I237-I241 HydrophobicContact CG2-CD1 3.65Å; I237-I241 HydrophobicContact CG2-CG1 4.42Å; I237-I241 WeakPolarHBondContact O-CB 3.39Å; I237-I241 VanDerWaalsContact O-CG1 3.28Å; I237-I241 WeakPolarHBondContact O-CG1 3.43Å; I237-I241 PolarHBondContact O-N 3.05Å; I241-K245 WeakPolarHBondContact O-CG 3.39Å; I241-K245 PolarHBondContact O-N 3.36Å; I241-K245 VanDerWaalsContact O-N 3.15Å
242	G	87	Confident	83.3	Confident	27 Å²	27	51 Å²	51	28%	0.278	29%	0.287	S	S	.	.	H	α-helix	trans	-64	-47.5	177.8	0	0	0	0	0	112.5	G238 V239 I240 R244 K245 I246	G238-G242 PolarHBondContact O-N 2.95Å; V239-G242 PolarHBondContact O-N 2.77Å; I240-G242 VanDerWaalsContact C-N 3.33Å; I240-G242 PolarHBondContact O-N 3.34Å; G242-R244 VanDerWaalsContact C-N 3.31Å; G242-R244 PolarHBondContact O-N 3.48Å; G242-K245 PolarHBondContact O-N 3.46Å; G242-K245 VanDerWaalsContact O-N 3.14Å; G242-I246 WeakPolarHBondContact O-CG1 3.32Å; G242-I246 PolarHBondContact O-N 2.68Å; G242-I246 VanDerWaalsContact O-N 3.17Å
243	S	84.2	Confident	82.7	Confident	10 Å²	10	53 Å²	53	7%	0.07	30%	0.299	C	S	.	.	H	α-helix	trans	-58.9	-44.6	178.3	-57.9	0	0	0	0	110.7	V239 I240 K245 I246 G247 I248	V239-S243 VanDerWaalsContact O-CB 3.27Å; V239-S243 WeakPolarHBondContact O-CB 3.4Å; V239-S243 PolarHBondContact O-N 3.36Å; V239-S243 PolarHBondContact O-OG 3.03Å; I240-S243 PolarHBondContact O-N 3.39Å; S243-K245 VanDerWaalsContact C-N 3.35Å; S243-K245 PolarHBondContact O-N 2.55Å; S243-I246 CarbonylContact O-C 3.57Å; S243-I246 PolarHBondContact O-N 3.47Å; S243-I246 VanDerWaalsContact O-N 3.12Å; S243-G247 PolarHBondContact O-N 3.02Å; S243-I248 CarbonylContact C-O 3.5Å; S243-I248 VanDerWaalsContact C-O 3.28Å; S243-I248 WeakPolarHBondContact CB-O 3.29Å; S243-I248 PolarHBondContact O-N 3.38Å; S243-I248 VanDerWaalsContact O-O 3.12Å
244	R	79.8	Confident	82.2	Confident	88 Å²	88	53 Å²	53	33%	0.332	30%	0.299	S	S	.	.	H	α-helix	trans	-58.5	-42.7	175.7	-165.3	-178.3	-153	-132.5	-5.9	112.9	A161 M166 D167 I240 G242 I246 G247	A161-R244 PolarHBondContact O-NE 3.37Å; A161-R244 PolarHBondContact O-NH2 3.26Å; M166-R244 PolarHBondContact O-NH1 2.94Å; D167-R244 IonicContact OD1-CZ 2.91Å; D167-R244 IonicContact OD1-NH1 2.76Å; D167-R244 PolarHBondContact OD1-NH1 3.14Å; D167-R244 IonicContact OD1-NH2 3.97Å; D167-R244 PolarHBondContact OD1-NH2 2.94Å; I240-R244 WeakPolarHBondContact O-CB 3.36Å; I240-R244 PolarHBondContact O-N 3.11Å; I240-R244 VanDerWaalsContact O-N 3.08Å; G242-R244 VanDerWaalsContact C-N 3.31Å; G242-R244 PolarHBondContact O-N 3.48Å; R244-I246 VanDerWaalsContact C-N 3.26Å; R244-I246 PolarHBondContact O-N 3.1Å; R244-G247 PolarHBondContact O-N 3.35Å
245	K	83.7	Confident	81.4	Confident	176 Å²	176	49.7 Å²	49.7	77%	0.765	29%	0.285	S	S	*	.	H	α-helix	trans	-66.2	-28.3	178.4	-75	179	178.6	-177.5	0	113.2	I241 G242 S243	I241-K245 WeakPolarHBondContact O-CG 3.39Å; I241-K245 PolarHBondContact O-N 3.36Å; I241-K245 VanDerWaalsContact O-N 3.15Å; G242-K245 PolarHBondContact O-N 3.46Å; G242-K245 VanDerWaalsContact O-N 3.14Å; S243-K245 VanDerWaalsContact C-N 3.35Å; S243-K245 PolarHBondContact O-N 2.55Å
246	I	85.4	Confident	80.8	Confident	129 Å²	129	47.7 Å²	47.7	66%	0.662	28%	0.276	S	S	*	.	H	α-helix	trans	-91.6	-7.7	179.5	-56.9	166.1	0	0	0	110.9	G242 S243 R244 I248	G242-I246 WeakPolarHBondContact O-CG1 3.32Å; G242-I246 PolarHBondContact O-N 2.68Å; G242-I246 VanDerWaalsContact O-N 3.17Å; S243-I246 CarbonylContact O-C 3.57Å; S243-I246 PolarHBondContact O-N 3.47Å; S243-I246 VanDerWaalsContact O-N 3.12Å; R244-I246 VanDerWaalsContact C-N 3.26Å; R244-I246 PolarHBondContact O-N 3.1Å; I246-I248 VanDerWaalsContact C-N 3.3Å; I246-I248 HydrophobicContact CB-CD1 4.44Å; I246-I248 HydrophobicContact CB-CG1 4.42Å; I246-I248 HydrophobicContact CG2-CD1 3.87Å; I246-I248 HydrophobicContact CG2-CG1 4.03Å
247	G	75.7	Confident	80.6	Confident	71 Å²	71	49.2 Å²	49.2	73%	0.732	28%	0.283	S	S	*	.	T	Hydrogen-bonded Turn	trans	77.1	15.1	-176.9	0	0	0	0	0	113.7	S243 R244	S243-G247 PolarHBondContact O-N 3.02Å; R244-G247 PolarHBondContact O-N 3.35Å
248	I	73.1	Confident	80.5	Confident	80 Å²	80	48.7 Å²	48.7	41%	0.41	28%	0.281	S	S	.	.			trans	-87.6	134.1	173.6	-58.7	172.9	0	0	0	107.9	S243 I246 P250 V253	S243-I248 CarbonylContact C-O 3.5Å; S243-I248 VanDerWaalsContact C-O 3.28Å; S243-I248 WeakPolarHBondContact CB-O 3.29Å; S243-I248 PolarHBondContact O-N 3.38Å; S243-I248 VanDerWaalsContact O-O 3.12Å; I246-I248 VanDerWaalsContact C-N 3.3Å; I246-I248 HydrophobicContact CB-CD1 4.44Å; I246-I248 HydrophobicContact CB-CG1 4.42Å; I246-I248 HydrophobicContact CG2-CD1 3.87Å; I246-I248 HydrophobicContact CG2-CG1 4.03Å; I248-P250 WeakPolarHBondContact O-CD 3.38Å; I248-P250 VanDerWaalsContact O-N 3.14Å; I248-V253 HydrophobicContact CG2-CG2 3.59Å
249	N	71.6	Confident	80.2	Confident	55 Å²	55	46.8 Å²	46.8	29%	0.294	26%	0.261	S	S	.	.			trans	-59.3	118.9	174.9	-175.2	-16.2	0	0	0	109.4	N162 D251 N252	N162-N249 PolarHBondContact ND2-OD1 3.43Å; N249-D251 PolarHBondContact O-N 3.15Å; N249-D251 VanDerWaalsContact O-N 3.16Å; N249-D251 WeakPolarHBondContact OD1-CB 3.13Å; N249-D251 PolarHBondContact OD1-N 3.04Å; N249-D251 PolarHBondContact OD1-OD2 3.07Å; N249-N252 PolarHBondContact O-N 2.93Å; N249-N252 VanDerWaalsContact O-N 3.14Å
250	P	71.6	Confident	80	Confident	3 Å²	3	46 Å²	46	2%	0.019	26%	0.256	C	S	.	.	T	Hydrogen-bonded Turn	trans	-58.5	-27.6	-178.5	24.2	-35.1	0	0	0	113.1	A161 I240 I248 N252 V253 A254	A161-P250 HydrophobicContact CB-CG 4.28Å; I240-P250 HydrophobicContact CB-CB 4.28Å; I240-P250 HydrophobicContact CG1-CB 4.16Å; I240-P250 HydrophobicContact CG2-CB 3.98Å; I240-P250 HydrophobicContact CG2-CG 4.45Å; I248-P250 WeakPolarHBondContact O-CD 3.38Å; I248-P250 VanDerWaalsContact O-N 3.14Å; P250-N252 VanDerWaalsContact C-N 3.26Å; P250-N252 PolarHBondContact O-N 3.44Å; P250-V253 PolarHBondContact O-N 3.31Å; P250-A254 WeakPolarHBondContact O-CB 3.11Å; P250-A254 PolarHBondContact O-N 3.39Å
251	D	69	Low	80.3	Confident	53 Å²	53	48.7 Å²	48.7	28%	0.283	27%	0.271	S	S	.	.	H	α-helix	trans	-61.4	-33.2	178.1	-69.6	-42.9	0	0	0	113.4	S158 N162 N249 V253	S158-D251 WeakPolarHBondContact CB-OD1 3.25Å; S158-D251 PolarHBondContact OG-OD1 2.78Å; N162-D251 PolarHBondContact ND2-OD2 3.1Å; N162-D251 VanDerWaalsContact ND2-OD2 3.14Å; N249-D251 PolarHBondContact O-N 3.15Å; N249-D251 VanDerWaalsContact O-N 3.16Å; N249-D251 WeakPolarHBondContact OD1-CB 3.13Å; N249-D251 PolarHBondContact OD1-N 3.04Å; N249-D251 PolarHBondContact OD1-OD2 3.07Å; D251-V253 VanDerWaalsContact C-N 3.28Å; D251-V253 PolarHBondContact O-N 3.45Å
252	N	69.7	Low	80.5	Confident	90 Å²	90	46.5 Å²	46.5	48%	0.481	26%	0.26	S	S	.	.	H	α-helix	trans	-76.8	-17.1	-177.1	-66.8	-14.2	0	0	0	113	N249 P250	N249-N252 PolarHBondContact O-N 2.93Å; N249-N252 VanDerWaalsContact O-N 3.14Å; P250-N252 VanDerWaalsContact C-N 3.26Å; P250-N252 PolarHBondContact O-N 3.44Å
253	V	78.3	Confident	80.7	Confident	43 Å²	43	45.7 Å²	45.7	26%	0.261	25%	0.249	S	C	.	.	H	α-helix	trans	-119.2	-37.1	-171.9	-175.3	0	0	0	0	111.4	V239 I248 P250 D251 P256 I257	V239-V253 HydrophobicContact CG1-CB 4.36Å; V239-V253 HydrophobicContact CG1-CG1 3.83Å; I248-V253 HydrophobicContact CG2-CG2 3.59Å; P250-V253 PolarHBondContact O-N 3.31Å; D251-V253 VanDerWaalsContact C-N 3.28Å; D251-V253 PolarHBondContact O-N 3.45Å; V253-P256 WeakPolarHBondContact O-CD 3.45Å; V253-I257 HydrophobicContact CG1-CD1 3.55Å; V253-I257 HydrophobicContact CG1-CG1 4.41Å; V253-I257 WeakPolarHBondContact O-CB 3.4Å; V253-I257 WeakPolarHBondContact O-CD1 3.41Å; V253-I257 WeakPolarHBondContact O-CG1 3.14Å; V253-I257 PolarHBondContact O-N 3.1Å
254	A	81.8	Confident	81.2	Confident	0 Å²	0	47.7 Å²	47.7	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-68.5	-55.9	-175.1	0	0	0	0	0	111.6	A154 M236 V239 I240 P250 I257 A258	A154-A254 HydrophobicContact CB-CB 4.15Å; M236-A254 HydrophobicContact CE-CB 3.46Å; M236-A254 VanDerWaalsContact CE-CB 3.46Å; M236-A254 WeakPolarHBondContact CE-O 3.49Å; V239-A254 HydrophobicContact CG1-CB 4.22Å; I240-A254 HydrophobicContact CD1-CB 4.33Å; I240-A254 HydrophobicContact CG1-CB 3.81Å; P250-A254 WeakPolarHBondContact O-CB 3.11Å; P250-A254 PolarHBondContact O-N 3.39Å; A254-I257 PolarHBondContact O-N 3.34Å; A254-A258 WeakPolarHBondContact O-CB 3.48Å; A254-A258 PolarHBondContact O-N 2.91Å
255	T	76.3	Confident	81.9	Confident	38 Å²	38	45.2 Å²	45.2	23%	0.233	25%	0.252	C	S	.	.	H	α-helix	trans	-56.1	-43.8	-177.1	-49.9	0	0	0	0	113	M151 A258 A259	M151-T255 HydrophobicContact SD-CG2 4.34Å; T255-A258 WeakPolarHBondContact O-CB 3.35Å; T255-A258 PolarHBondContact O-N 3.48Å; T255-A259 WeakPolarHBondContact O-CB 3.49Å; T255-A259 PolarHBondContact O-N 2.89Å
256	P	79.7	Confident	82.4	Confident	12 Å²	12	37 Å²	37	8%	0.078	22%	0.216	C	C	.	.	H	α-helix	trans	-71	-35.2	179.4	-23.5	39.2	0	0	0	113.8	P105 L108 V253 A259 S260	P105-P256 HydrophobicContact CB-CB 3.9Å; P105-P256 HydrophobicContact CB-CG 3.33Å; P105-P256 HydrophobicContact CG-CG 3.88Å; L108-P256 HydrophobicContact CD2-CB 4.41Å; V253-P256 WeakPolarHBondContact O-CD 3.45Å; P256-A259 WeakPolarHBondContact O-CB 3.34Å; P256-A259 PolarHBondContact O-N 2.94Å; P256-S260 WeakPolarHBondContact O-CB 3.26Å; P256-S260 PolarHBondContact O-N 3.28Å; P256-S260 PolarHBondContact O-OG 3.29Å
257	I	85.4	Confident	82.9	Confident	32 Å²	32	31 Å²	31	16%	0.164	19%	0.185	C	C	.	.	H	α-helix	trans	-69	-41.5	174.5	-69.2	177.6	0	0	0	110.4	L108 I235 M236 V239 V253 A254 A259 S260 L261	L108-I257 HydrophobicContact CD2-CG1 3.86Å; I235-I257 HydrophobicContact CG2-CG2 4.37Å; M236-I257 HydrophobicContact SD-CG2 4.38Å; V239-I257 HydrophobicContact CG1-CD1 4.02Å; V239-I257 HydrophobicContact CG2-CD1 3.95Å; V239-I257 HydrophobicContact CG2-CG2 4.17Å; V253-I257 HydrophobicContact CG1-CD1 3.55Å; V253-I257 HydrophobicContact CG1-CG1 4.41Å; V253-I257 WeakPolarHBondContact O-CB 3.4Å; V253-I257 WeakPolarHBondContact O-CD1 3.41Å; V253-I257 WeakPolarHBondContact O-CG1 3.14Å; V253-I257 PolarHBondContact O-N 3.1Å; A254-I257 PolarHBondContact O-N 3.34Å; I257-A259 VanDerWaalsContact C-N 3.28Å; I257-A259 PolarHBondContact O-N 2.87Å; I257-S260 PolarHBondContact O-N 2.74Å; I257-S260 PolarHBondContact O-OG 2.97Å; I257-L261 HydrophobicContact CG2-CD1 3.62Å; I257-L261 HydrophobicContact CG2-CG 4.15Å; I257-L261 WeakPolarHBondContact O-CB 3.28Å; I257-L261 PolarHBondContact O-N 2.8Å
258	A	86.3	Confident	83.9	Confident	1 Å²	1	29.8 Å²	29.8	1%	0.008	17%	0.168	C	C	.	.	H	α-helix	trans	-58.1	-45.2	173.1	0	0	0	0	0	110.4	K146 E150 M236 A254 T255 G262	K146-A258 PolarHBondContact NZ-O 2.83Å; E150-A258 HydrophobicContact CB-CB 4.44Å; M236-A258 HydrophobicContact CE-CB 3.84Å; M236-A258 HydrophobicContact CG-CB 4.19Å; M236-A258 VanDerWaalsContact SD-CA 3.57Å; M236-A258 HydrophobicContact SD-CB 3.54Å; M236-A258 VanDerWaalsContact SD-CB 3.54Å; A254-A258 WeakPolarHBondContact O-CB 3.48Å; A254-A258 PolarHBondContact O-N 2.91Å; T255-A258 WeakPolarHBondContact O-CB 3.35Å; T255-A258 PolarHBondContact O-N 3.48Å; A258-G262 VanDerWaalsContact O-CA 3.28Å; A258-G262 WeakPolarHBondContact O-CA 3.15Å; A258-G262 PolarHBondContact O-N 2.97Å
259	A	84.1	Confident	85	Confident	2 Å²	2	28 Å²	28	2%	0.017	16%	0.16	C	C	.	.	H	α-helix	trans	-57.8	-57.4	174.9	0	0	0	0	0	111.1	A109 K146 T255 P256 I257 N362	A109-A259 HydrophobicContact CB-CB 3.77Å; K146-A259 VanDerWaalsContact NZ-CA 3.26Å; K146-A259 PolarHBondContact NZ-O 3.23Å; T255-A259 WeakPolarHBondContact O-CB 3.49Å; T255-A259 PolarHBondContact O-N 2.89Å; P256-A259 WeakPolarHBondContact O-CB 3.34Å; P256-A259 PolarHBondContact O-N 2.94Å; I257-A259 VanDerWaalsContact C-N 3.28Å; I257-A259 PolarHBondContact O-N 2.87Å; A259-N362 WeakPolarHBondContact CB-OD1 3.36Å
260	S	85.7	Confident	86.3	Confident	8 Å²	8	25.5 Å²	25.5	6%	0.056	15%	0.146	C	C	.	.	H	α-helix	trans	-66.1	-53.9	-172.1	71.7	0	0	0	0	113.5	L108 G112 P256 I257 G262	L108-S260 WeakPolarHBondContact O-CB 3.48Å; G112-S260 WeakPolarHBondContact CA-O 3.38Å; P256-S260 WeakPolarHBondContact O-CB 3.26Å; P256-S260 PolarHBondContact O-N 3.28Å; P256-S260 PolarHBondContact O-OG 3.29Å; I257-S260 PolarHBondContact O-N 2.74Å; I257-S260 PolarHBondContact O-OG 2.97Å; S260-G262 VanDerWaalsContact C-N 3.28Å
261	L	90.8	Very high	87.5	Confident	59 Å²	59	25.4 Å²	25.4	31%	0.309	15%	0.145	S	C	.	.	H	α-helix	trans	-74	-29.7	-176.9	-68.4	-179	0	0	0	111.1	L232 I235 I257 D263 I265	L232-L261 HydrophobicContact CD2-CB 4.08Å; I235-L261 HydrophobicContact CD1-CD1 4.36Å; I235-L261 HydrophobicContact CG2-CD1 3.96Å; I257-L261 HydrophobicContact CG2-CD1 3.62Å; I257-L261 HydrophobicContact CG2-CG 4.15Å; I257-L261 WeakPolarHBondContact O-CB 3.28Å; I257-L261 PolarHBondContact O-N 2.8Å; L261-D263 PolarHBondContact O-N 2.93Å; L261-I265 HydrophobicContact CB-CD1 4.09Å; L261-I265 VanDerWaalsContact O-CB 3.23Å; L261-I265 WeakPolarHBondContact O-CB 3.49Å; L261-I265 VanDerWaalsContact O-CG1 3.24Å; L261-I265 WeakPolarHBondContact O-CG1 3.44Å; L261-I265 PolarHBondContact O-N 3.26Å
262	G	91	Very high	88.8	Confident	0 Å²	0	24.6 Å²	24.6	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-61	-46.8	-174.8	0	0	0	0	0	113.3	K146 A258 S260 T266	K146-G262 WeakPolarHBondContact CD-O 3.25Å; K146-G262 VanDerWaalsContact CE-CA 3.49Å; A258-G262 VanDerWaalsContact O-CA 3.28Å; A258-G262 WeakPolarHBondContact O-CA 3.15Å; A258-G262 PolarHBondContact O-N 2.97Å; S260-G262 VanDerWaalsContact C-N 3.28Å; G262-T266 WeakPolarHBondContact O-CB 3.11Å; G262-T266 PolarHBondContact O-N 2.95Å; G262-T266 PolarHBondContact O-OG1 3.42Å
263	D	91.3	Very high	90.1	Very high	10 Å²	10	21.8 Å²	21.8	5%	0.053	14%	0.135	C	C	.	.	H	α-helix	trans	-71.4	-43.4	-174.4	-74.4	-30.1	0	0	0	109.4	T113 A116 L143 K146 L261 L267	T113-D263 WeakPolarHBondContact CG2-OD2 2.88Å; A116-D263 HydrophobicContact CB-CB 3.74Å; L143-D263 HydrophobicContact CD2-CB 4.08Å; K146-D263 WeakPolarHBondContact CD-OD1 3.19Å; K146-D263 WeakPolarHBondContact CE-OD1 3.42Å; K146-D263 IonicContact NZ-OD1 2.6Å; L261-D263 PolarHBondContact O-N 2.93Å; D263-L267 VanDerWaalsContact O-CB 3.24Å; D263-L267 WeakPolarHBondContact O-CB 3.34Å; D263-L267 PolarHBondContact O-N 3.17Å
264	L	94.2	Very high	91	Very high	52 Å²	52	19.8 Å²	19.8	27%	0.272	12%	0.122	S	C	.	.	H	α-helix	trans	-59.2	-51.7	177.1	178.1	59.6	0	0	0	112	A115 V119 A268	A115-L264 HydrophobicContact CB-CD1 4.01Å; A115-L264 HydrophobicContact CB-CD2 4.08Å; V119-L264 HydrophobicContact CG2-CD1 3.73Å; L264-A268 WeakPolarHBondContact O-CB 3.38Å; L264-A268 PolarHBondContact O-N 3.02Å
265	I	95	Very high	91.6	Very high	36 Å²	36	23.5 Å²	23.5	19%	0.185	14%	0.137	C	C	.	.	H	α-helix	trans	-66.4	-45.1	-178.1	-71	175.7	0	0	0	110.5	V231 L232 I235 L261 L267 A268 L269	V231-I265 HydrophobicContact CG1-CD1 4.2Å; V231-I265 HydrophobicContact CG1-CG2 4.42Å; L232-I265 HydrophobicContact CD2-CB 4.33Å; L232-I265 HydrophobicContact CD2-CD1 3.79Å; L232-I265 HydrophobicContact CG-CG2 4.41Å; I235-I265 HydrophobicContact CD1-CD1 3.94Å; L261-I265 HydrophobicContact CB-CD1 4.09Å; L261-I265 VanDerWaalsContact O-CB 3.23Å; L261-I265 WeakPolarHBondContact O-CB 3.49Å; L261-I265 VanDerWaalsContact O-CG1 3.24Å; L261-I265 WeakPolarHBondContact O-CG1 3.44Å; L261-I265 PolarHBondContact O-N 3.26Å; I265-L267 PolarHBondContact O-N 3.32Å; I265-A268 PolarHBondContact O-N 3.48Å; I265-L269 HydrophobicContact CG2-CD1 3.63Å; I265-L269 HydrophobicContact CG2-CG 4.26Å; I265-L269 VanDerWaalsContact O-CB 3.27Å; I265-L269 WeakPolarHBondContact O-CB 3.32Å; I265-L269 VanDerWaalsContact O-CG 3.25Å; I265-L269 WeakPolarHBondContact O-CG 3.39Å; I265-L269 PolarHBondContact O-N 3.1Å
266	T	94.6	Very high	92.5	Very high	4 Å²	4	23.2 Å²	23.2	3%	0.025	14%	0.141	C	C	.	.	H	α-helix	trans	-62.1	-46.1	-178.7	-56.8	0	0	0	0	110.6	L142 L143 T224 A228 G262 L270	L142-T266 HydrophobicContact CB-CG2 3.87Å; L143-T266 HydrophobicContact CD2-CG2 4.12Å; T224-T266 HydrophobicContact CG2-CG2 4.24Å; T224-T266 WeakPolarHBondContact CG2-O 3.46Å; A228-T266 HydrophobicContact CB-CG2 4.49Å; G262-T266 WeakPolarHBondContact O-CB 3.11Å; G262-T266 PolarHBondContact O-N 2.95Å; G262-T266 PolarHBondContact O-OG1 3.42Å; T266-L270 WeakPolarHBondContact O-CB 3.41Å; T266-L270 PolarHBondContact O-N 2.99Å
267	L	95.1	Very high	93.2	Very high	1 Å²	1	23.3 Å²	23.3	1%	0.005	14%	0.141	C	C	.	.	H	α-helix	trans	-71.5	-40.1	-179.5	-174.6	64.5	0	0	0	112.8	A116 V119 L120 V139 L143 D263 I265 L269 L270 S271	A116-L267 HydrophobicContact CB-CD2 4.42Å; A116-L267 WeakPolarHBondContact O-CD2 3.49Å; V119-L267 HydrophobicContact CB-CD2 4.11Å; V119-L267 HydrophobicContact CG1-CD2 4.04Å; V119-L267 HydrophobicContact CG1-CG 4.02Å; L120-L267 HydrophobicContact CB-CD2 3.67Å; L120-L267 HydrophobicContact CD1-CD1 4.08Å; L120-L267 HydrophobicContact CD1-CD2 4.34Å; L120-L267 HydrophobicContact CG-CD2 4.44Å; V139-L267 HydrophobicContact CG1-CD1 4.01Å; V139-L267 HydrophobicContact CG2-CD1 3.75Å; L143-L267 HydrophobicContact CD2-CB 4.4Å; D263-L267 VanDerWaalsContact O-CB 3.24Å; D263-L267 WeakPolarHBondContact O-CB 3.34Å; D263-L267 PolarHBondContact O-N 3.17Å; I265-L267 PolarHBondContact O-N 3.32Å; L267-L269 VanDerWaalsContact C-N 3.33Å; L267-L269 PolarHBondContact O-N 3.17Å; L267-L270 HydrophobicContact CD1-CD2 4.49Å; L267-L270 PolarHBondContact O-N 3.11Å; L267-S271 WeakPolarHBondContact O-CB 3.48Å; L267-S271 PolarHBondContact O-N 3.41Å; L267-S271 PolarHBondContact O-OG 3.19Å
268	A	96.8	Very high	93.6	Very high	46 Å²	46	23.7 Å²	23.7	38%	0.38	14%	0.14	S	C	.	.	H	α-helix	trans	-62.3	-42.3	175.7	0	0	0	0	0	111.5	L264 I265 G272	L264-A268 WeakPolarHBondContact O-CB 3.38Å; L264-A268 PolarHBondContact O-N 3.02Å; I265-A268 PolarHBondContact O-N 3.48Å; A268-G272 PolarHBondContact O-N 3.02Å
269	L	97.2	Very high	93.8	Very high	44 Å²	44	27 Å²	27	23%	0.23	16%	0.158	C	C	.	.	H	α-helix	trans	-66.3	-45.5	174.6	-74.1	172.6	0	0	0	111.5	T224 I227 A228 I265 L267 S271 G272 I273	T224-L269 HydrophobicContact CG2-CB 4.03Å; I227-L269 HydrophobicContact CB-CD1 4.24Å; I227-L269 HydrophobicContact CG2-CD1 3.77Å; I227-L269 HydrophobicContact CG2-CD2 4.02Å; A228-L269 HydrophobicContact CB-CD1 3.79Å; I265-L269 HydrophobicContact CG2-CD1 3.63Å; I265-L269 HydrophobicContact CG2-CG 4.26Å; I265-L269 VanDerWaalsContact O-CB 3.27Å; I265-L269 WeakPolarHBondContact O-CB 3.32Å; I265-L269 VanDerWaalsContact O-CG 3.25Å; I265-L269 WeakPolarHBondContact O-CG 3.39Å; I265-L269 PolarHBondContact O-N 3.1Å; L267-L269 VanDerWaalsContact C-N 3.33Å; L267-L269 PolarHBondContact O-N 3.17Å; L269-S271 VanDerWaalsContact C-N 3.27Å; L269-S271 PolarHBondContact O-N 2.74Å; L269-G272 PolarHBondContact O-N 3.08Å; L269-I273 HydrophobicContact CB-CD1 4.22Å; L269-I273 HydrophobicContact CD2-CD1 4.5Å; L269-I273 WeakPolarHBondContact O-CB 3.37Å; L269-I273 WeakPolarHBondContact O-CD1 3.3Å; L269-I273 WeakPolarHBondContact O-CG1 3.14Å; L269-I273 PolarHBondContact O-N 3.08Å
270	L	97.3	Very high	94.1	Very high	1 Å²	1	30.9 Å²	30.9	1%	0.005	18%	0.175	C	C	.	.	H	α-helix	trans	-54	-50.3	176.2	-179.4	58.8	0	0	0	110.4	V135 L138 V139 L142 T224 T266 L267 S274	V135-L270 HydrophobicContact CG1-CD2 4.23Å; V135-L270 HydrophobicContact CG1-CG 4.31Å; L138-L270 HydrophobicContact CD2-CD1 3.71Å; L138-L270 HydrophobicContact CG-CD1 4.43Å; V139-L270 HydrophobicContact CG2-CD2 3.67Å; L142-L270 HydrophobicContact CD1-CD1 3.88Å; L142-L270 HydrophobicContact CD1-CD2 4.18Å; L142-L270 HydrophobicContact CD1-CG 4.46Å; T224-L270 HydrophobicContact CG2-CB 3.87Å; T224-L270 WeakPolarHBondContact OG1-CA 3.2Å; T266-L270 WeakPolarHBondContact O-CB 3.41Å; T266-L270 PolarHBondContact O-N 2.99Å; L267-L270 HydrophobicContact CD1-CD2 4.49Å; L267-L270 PolarHBondContact O-N 3.11Å; L270-S274 WeakPolarHBondContact O-CB 3.31Å; L270-S274 PolarHBondContact O-N 3.36Å; L270-S274 PolarHBondContact O-OG 2.65Å
271	S	97.1	Very high	93.9	Very high	1 Å²	1	33 Å²	33	1%	0.007	19%	0.186	C	C	.	.	H	α-helix	trans	-65.9	-48.1	-175.9	-52.5	0	0	0	0	111.3	V123 L267 L269 W275	V123-S271 WeakPolarHBondContact CG2-OG 3.29Å; L267-S271 WeakPolarHBondContact O-CB 3.48Å; L267-S271 PolarHBondContact O-N 3.41Å; L267-S271 PolarHBondContact O-OG 3.19Å; L269-S271 VanDerWaalsContact C-N 3.27Å; L269-S271 PolarHBondContact O-N 2.74Å; S271-W275 WeakPolarHBondContact O-CB 3.44Å; S271-W275 PolarHBondContact O-N 3.41Å
272	G	97.2	Very high	93.3	Very high	37 Å²	37	37.2 Å²	37.2	38%	0.381	21%	0.209	S	C	.	.	H	α-helix	trans	-65.2	-42.6	179.5	0	0	0	0	0	113.3	A268 L269 G276	A268-G272 PolarHBondContact O-N 3.02Å; L269-G272 PolarHBondContact O-N 3.08Å; G272-G276 PolarHBondContact O-N 3.02Å
273	I	96.8	Very high	92.9	Very high	31 Å²	31	44.3 Å²	44.3	16%	0.159	24%	0.241	C	C	.	.	H	α-helix	trans	-69.5	-45.5	179	-66.2	167.1	0	0	0	110.2	A223 I227 L269 W275 G276 L277	A223-I273 HydrophobicContact CB-CD1 4.2Å; A223-I273 HydrophobicContact CB-CG2 4.08Å; I227-I273 HydrophobicContact CD1-CD1 3.97Å; L269-I273 HydrophobicContact CB-CD1 4.22Å; L269-I273 HydrophobicContact CD2-CD1 4.5Å; L269-I273 WeakPolarHBondContact O-CB 3.37Å; L269-I273 WeakPolarHBondContact O-CD1 3.3Å; L269-I273 WeakPolarHBondContact O-CG1 3.14Å; L269-I273 PolarHBondContact O-N 3.08Å; I273-W275 PolarHBondContact O-N 3.13Å; I273-G276 PolarHBondContact O-N 3.43Å; I273-L277 HydrophobicContact CG2-CD1 3.71Å; I273-L277 HydrophobicContact CG2-CG 4.18Å; I273-L277 VanDerWaalsContact O-CB 3.31Å; I273-L277 WeakPolarHBondContact O-CB 3.37Å; I273-L277 VanDerWaalsContact O-CG 3.22Å; I273-L277 WeakPolarHBondContact O-CG 3.21Å; I273-L277 PolarHBondContact O-N 2.96Å
274	S	96.5	Very high	92.5	Very high	0 Å²	0	51.8 Å²	51.8	0%	0	27%	0.269	C	S	.	.	H	α-helix	trans	-61.2	-46.4	178.8	-55.8	0	0	0	0	111	S220 L270 Y278	S220-S274 VanDerWaalsContact CB-OG 3.24Å; S220-S274 WeakPolarHBondContact CB-OG 3.39Å; L270-S274 WeakPolarHBondContact O-CB 3.31Å; L270-S274 PolarHBondContact O-N 3.36Å; L270-S274 PolarHBondContact O-OG 2.65Å; S274-Y278 WeakPolarHBondContact O-CB 3.32Å; S274-Y278 PolarHBondContact O-N 2.88Å
275	W	96	Very high	91.9	Very high	79 Å²	79	59.4 Å²	59.4	30%	0.299	29%	0.294	S	S	.	.	H	α-helix	trans	-61	-50.5	175.5	175.3	-104.7	0	0	0	112.7	W126 E127 V128 S271 I273 L277 Y278 L279	W126-W275 HydrophobicContact CB-CE3 4.16Å; W126-W275 HydrophobicContact CB-CZ3 4.31Å; W126-W275 HydrophobicContact CE3-CB 3.72Å; W126-W275 HydrophobicContact CE3-CD2 4.07Å; W126-W275 HydrophobicContact CE3-CE3 4.21Å; W126-W275 AromaticContact CE3-CG 3.87Å; W126-W275 HydrophobicContact CE3-CG 3.87Å; W126-W275 HydrophobicContact CZ3-CB 3.7Å; W126-W275 AromaticContact CZ3-CG 3.9Å; W126-W275 HydrophobicContact CZ3-CG 3.9Å; E127-W275 HydrophobicContact CB-CH2 4.38Å; E127-W275 HydrophobicContact CB-CZ3 3.73Å; V128-W275 HydrophobicContact CB-CE3 4.36Å; V128-W275 HydrophobicContact CG1-CB 4.27Å; V128-W275 HydrophobicContact CG1-CE3 4.07Å; S271-W275 WeakPolarHBondContact O-CB 3.44Å; S271-W275 PolarHBondContact O-N 3.41Å; I273-W275 PolarHBondContact O-N 3.13Å; W275-L277 PolarHBondContact O-N 3.31Å; W275-Y278 PolarHBondContact O-N 3.01Å; W275-L279 HydrophobicContact CD2-CD1 4.34Å; W275-L279 HydrophobicContact CD2-CG 4.35Å; W275-L279 HydrophobicContact CH2-CD2 4.16Å; W275-L279 HydrophobicContact CZ2-CD1 3.75Å; W275-L279 HydrophobicContact CZ2-CD2 3.93Å; W275-L279 HydrophobicContact CZ2-CG 4.06Å; W275-L279 VanDerWaalsContact NE1-CD1 3.3Å; W275-L279 PolarHBondContact O-N 3.4Å
276	G	94.6	Very high	91.5	Very high	31 Å²	31	66.2 Å²	66.2	32%	0.32	32%	0.319	S	S	.	.	H	α-helix	trans	-60.7	-45	-179.3	0	0	0	0	0	112.4	G272 I273 L279 E280	G272-G276 PolarHBondContact O-N 3.02Å; I273-G276 PolarHBondContact O-N 3.43Å; G276-L279 PolarHBondContact O-N 3.05Å; G276-E280 WeakPolarHBondContact O-CG 3.38Å; G276-E280 PolarHBondContact O-N 2.92Å
277	L	94.9	Very high	91.4	Very high	15 Å²	15	67.5 Å²	67.5	8%	0.079	33%	0.325	C	S	.	.	H	α-helix	trans	-63.9	-41.7	175.3	-70.3	177.4	0	0	0	111.6	L216 A219 I273 W275 L279 E280 L281 I287 Y288 V291	L216-L277 HydrophobicContact CD1-CB 3.6Å; L216-L277 HydrophobicContact CD1-CD1 4.37Å; A219-L277 HydrophobicContact CB-CD1 3.74Å; I273-L277 HydrophobicContact CG2-CD1 3.71Å; I273-L277 HydrophobicContact CG2-CG 4.18Å; I273-L277 VanDerWaalsContact O-CB 3.31Å; I273-L277 WeakPolarHBondContact O-CB 3.37Å; I273-L277 VanDerWaalsContact O-CG 3.22Å; I273-L277 WeakPolarHBondContact O-CG 3.21Å; I273-L277 PolarHBondContact O-N 2.96Å; W275-L277 PolarHBondContact O-N 3.31Å; L277-L279 PolarHBondContact O-N 3.44Å; L277-E280 PolarHBondContact O-N 2.84Å; L277-L281 PolarHBondContact O-N 3.3Å; L277-I287 HydrophobicContact CD2-CD1 4.1Å; L277-I287 HydrophobicContact CD2-CG1 4.1Å; L277-Y288 HydrophobicContact CB-CD1 4.25Å; L277-Y288 HydrophobicContact CB-CE1 3.86Å; L277-Y288 VanDerWaalsContact O-CE1 3.28Å; L277-Y288 WeakPolarHBondContact O-CE1 3.34Å; L277-Y288 PolarHBondContact O-OH 3.11Å; L277-V291 HydrophobicContact CD2-CG2 4Å
278	Y	93.4	Very high	91.2	Very high	40 Å²	40	67.9 Å²	67.9	16%	0.157	33%	0.326	C	S	.	.	H	α-helix	trans	-60.8	-43.8	178.8	-179.3	-96.8	0	0	0	112.2	E127 V128 K131 L216 S274 W275 L281	E127-Y278 HydrophobicContact CB-CE1 4.36Å; E127-Y278 HydrophobicContact CG-CE1 4.14Å; E127-Y278 WeakPolarHBondContact OE1-CE1 3.29Å; E127-Y278 PolarHBondContact OE1-OH 2.99Å; V128-Y278 HydrophobicContact CB-CD1 4.24Å; V128-Y278 HydrophobicContact CB-CD2 4.49Å; V128-Y278 HydrophobicContact CB-CG 4Å; V128-Y278 HydrophobicContact CG2-CD2 4.13Å; V128-Y278 HydrophobicContact CG2-CG 3.93Å; K131-Y278 WeakPolarHBondContact CD-OH 3.1Å; K131-Y278 PolarHBondContact NZ-OH 3.02Å; L216-Y278 HydrophobicContact CD2-CD2 4.09Å; S274-Y278 WeakPolarHBondContact O-CB 3.32Å; S274-Y278 PolarHBondContact O-N 2.88Å; W275-Y278 PolarHBondContact O-N 3.01Å; Y278-L281 WeakPolarHBondContact O-CB 3.28Å; Y278-L281 PolarHBondContact O-N 3.49Å
279	L	91.2	Very high	91	Very high	71 Å²	71	68 Å²	68	37%	0.372	32%	0.324	S	S	.	.	H	α-helix	trans	-64.9	-39.9	176.5	-70.9	-178.2	0	0	0	113.3	W275 G276 L277 L281	W275-L279 HydrophobicContact CD2-CD1 4.34Å; W275-L279 HydrophobicContact CD2-CG 4.35Å; W275-L279 HydrophobicContact CH2-CD2 4.16Å; W275-L279 HydrophobicContact CZ2-CD1 3.75Å; W275-L279 HydrophobicContact CZ2-CD2 3.93Å; W275-L279 HydrophobicContact CZ2-CG 4.06Å; W275-L279 VanDerWaalsContact NE1-CD1 3.3Å; W275-L279 PolarHBondContact O-N 3.4Å; G276-L279 PolarHBondContact O-N 3.05Å; L277-L279 PolarHBondContact O-N 3.44Å; L279-L281 VanDerWaalsContact C-N 3.26Å; L279-L281 PolarHBondContact O-N 3.48Å
280	E	88.9	Confident	90.8	Very high	82 Å²	82	71.2 Å²	71.2	38%	0.383	34%	0.34	S	S	.	.	H	α-helix	trans	-74.8	-13.5	-177.5	-71.5	-60.2	153.5	0	0	113.7	G276 L277 N282 H283 W284 I287	G276-E280 WeakPolarHBondContact O-CG 3.38Å; G276-E280 PolarHBondContact O-N 2.92Å; L277-E280 PolarHBondContact O-N 2.84Å; E280-N282 PolarHBondContact O-N 3.48Å; E280-H283 PolarHBondContact O-N 2.84Å; E280-W284 PolarHBondContact O-N 2.86Å; E280-I287 HydrophobicContact CB-CD1 3.53Å; E280-I287 HydrophobicContact CG-CD1 4.11Å
281	L	82.6	Confident	90.6	Very high	53 Å²	53	72.6 Å²	72.6	28%	0.277	35%	0.349	S	S	.	.	T	Hydrogen-bonded Turn	trans	-55.4	-37.4	178.6	-177.7	58.3	0	0	0	112.7	L277 Y278 L279 H283 Y288	L277-L281 PolarHBondContact O-N 3.3Å; Y278-L281 WeakPolarHBondContact O-CB 3.28Å; Y278-L281 PolarHBondContact O-N 3.49Å; L279-L281 VanDerWaalsContact C-N 3.26Å; L279-L281 PolarHBondContact O-N 3.48Å; L281-H283 PolarHBondContact O-N 3.44Å; L281-Y288 HydrophobicContact CB-CE1 4.43Å; L281-Y288 WeakPolarHBondContact CB-OH 3.07Å; L281-Y288 HydrophobicContact CD1-CD2 4.23Å; L281-Y288 HydrophobicContact CD1-CE1 4.38Å; L281-Y288 HydrophobicContact CD1-CE2 3.56Å; L281-Y288 HydrophobicContact CD2-CE2 4.03Å; L281-Y288 WeakPolarHBondContact CD2-OH 3.32Å; L281-Y288 HydrophobicContact CG-CE2 4.24Å
282	N	77.1	Confident	90.4	Very high	148 Å²	148	73.3 Å²	73.3	79%	0.791	35%	0.353	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.1	-26.8	-179.7	-70.3	-36.5	0	0	0	112.6	E280	E280-N282 PolarHBondContact O-N 3.48Å
283	H	82.5	Confident	90.2	Very high	149 Å²	149	74.3 Å²	74.3	69%	0.69	36%	0.358	S	S	*	.	T	Hydrogen-bonded Turn	trans	-96	-41.2	-178.2	-64.5	95.9	0	0	0	111.8	E280 L281	E280-H283 PolarHBondContact O-N 2.84Å; L281-H283 PolarHBondContact O-N 3.44Å
284	W	84.6	Confident	90.1	Very high	167 Å²	167	78.6 Å²	78.6	63%	0.633	38%	0.376	S	S	*	.			trans	-127.2	90.4	-171.9	-67.6	72.4	0	0	0	111.7	E280 Y286 I287	E280-W284 PolarHBondContact O-N 2.86Å; W284-Y286 PolarHBondContact O-N 2.85Å; W284-I287 HydrophobicContact CB-CB 3.96Å; W284-I287 WeakPolarHBondContact O-CB 3.46Å; W284-I287 VanDerWaalsContact O-CG2 3.25Å; W284-I287 WeakPolarHBondContact O-CG2 3.45Å; W284-I287 PolarHBondContact O-N 2.83Å
285	R	80.3	Confident	90	Very high	212 Å²	212	79.4 Å²	79.4	80%	0.8	38%	0.379	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.9	-23.2	-177.2	-171	168.6	-178	159.9	1.5	115.2
286	Y	87.8	Confident	89.8	Confident	179 Å²	179	79.1 Å²	79.1	70%	0.702	39%	0.386	S	S	*	.	T	Hydrogen-bonded Turn	trans	-105.4	11.7	-178.2	-59.1	-70.6	0	0	0	113.9	W284 Y288 P289 L290	W284-Y286 PolarHBondContact O-N 2.85Å; Y286-Y288 PolarHBondContact O-N 2.87Å; Y286-P289 VanDerWaalsContact O-CD 3.31Å; Y286-P289 WeakPolarHBondContact O-CD 3.35Å; Y286-P289 WeakPolarHBondContact O-CG 3.3Å; Y286-L290 VanDerWaalsContact O-CB 3.28Å; Y286-L290 WeakPolarHBondContact O-CB 3.48Å; Y286-L290 PolarHBondContact O-N 3.34Å
287	I	91.1	Very high	89.8	Confident	31 Å²	31	81 Å²	81	16%	0.159	40%	0.398	C	S	.	.	H	α-helix	trans	-62.4	-42.7	-176.1	-165.9	170.9	0	0	0	112.5	L277 E280 W284 L290 V291	L277-I287 HydrophobicContact CD2-CD1 4.1Å; L277-I287 HydrophobicContact CD2-CG1 4.1Å; E280-I287 HydrophobicContact CB-CD1 3.53Å; E280-I287 HydrophobicContact CG-CD1 4.11Å; W284-I287 HydrophobicContact CB-CB 3.96Å; W284-I287 WeakPolarHBondContact O-CB 3.46Å; W284-I287 VanDerWaalsContact O-CG2 3.25Å; W284-I287 WeakPolarHBondContact O-CG2 3.45Å; W284-I287 PolarHBondContact O-N 2.83Å; I287-L290 PolarHBondContact O-N 3.42Å; I287-V291 HydrophobicContact CG1-CG2 4.36Å; I287-V291 VanDerWaalsContact O-CG2 3.31Å; I287-V291 WeakPolarHBondContact O-CG2 3.44Å; I287-V291 PolarHBondContact O-N 2.88Å
288	Y	92.2	Very high	89.7	Confident	8 Å²	8	82.6 Å²	82.6	3%	0.031	41%	0.407	C	S	.	.	H	α-helix	trans	-61.1	-54.8	-179.4	-51.7	-24.5	0	0	0	113.9	F215 L216 L277 L281 Y286 L290 V291 C292	F215-Y288 HydrophobicContact CB-CD2 3.84Å; F215-Y288 HydrophobicContact CB-CG 4.23Å; L216-Y288 HydrophobicContact CB-CD2 4.19Å; L216-Y288 HydrophobicContact CB-CE1 4.41Å; L216-Y288 HydrophobicContact CB-CE2 3.81Å; L216-Y288 HydrophobicContact CD1-CD1 4.35Å; L216-Y288 HydrophobicContact CD1-CE1 3.75Å; L277-Y288 HydrophobicContact CB-CD1 4.25Å; L277-Y288 HydrophobicContact CB-CE1 3.86Å; L277-Y288 VanDerWaalsContact O-CE1 3.28Å; L277-Y288 WeakPolarHBondContact O-CE1 3.34Å; L277-Y288 PolarHBondContact O-OH 3.11Å; L281-Y288 HydrophobicContact CB-CE1 4.43Å; L281-Y288 WeakPolarHBondContact CB-OH 3.07Å; L281-Y288 HydrophobicContact CD1-CD2 4.23Å; L281-Y288 HydrophobicContact CD1-CE1 4.38Å; L281-Y288 HydrophobicContact CD1-CE2 3.56Å; L281-Y288 HydrophobicContact CD2-CE2 4.03Å; L281-Y288 WeakPolarHBondContact CD2-OH 3.32Å; L281-Y288 HydrophobicContact CG-CE2 4.24Å; Y286-Y288 PolarHBondContact O-N 2.87Å; Y288-L290 VanDerWaalsContact C-N 3.26Å; Y288-L290 PolarHBondContact O-N 3.35Å; Y288-V291 PolarHBondContact O-N 3.12Å; Y288-C292 PolarHBondContact O-N 3.44Å; Y288-C292 VanDerWaalsContact O-N 3.1Å; Y288-C292 PolarHBondContact O-SG 2.98Å
289	P	91.2	Very high	89.7	Confident	49 Å²	49	82.9 Å²	82.9	32%	0.318	41%	0.411	S	S	.	.	H	α-helix	trans	-65.3	-30.7	178.2	25.2	-34.9	0	0	0	112.4	F215 Y286 C292 A293	F215-P289 HydrophobicContact CD1-CB 4.45Å; F215-P289 HydrophobicContact CE1-CB 4.37Å; Y286-P289 VanDerWaalsContact O-CD 3.31Å; Y286-P289 WeakPolarHBondContact O-CD 3.35Å; Y286-P289 WeakPolarHBondContact O-CG 3.3Å; P289-C292 PolarHBondContact O-N 3.23Å; P289-A293 VanDerWaalsContact O-CB 3.23Å; P289-A293 WeakPolarHBondContact O-CB 3.43Å; P289-A293 PolarHBondContact O-N 2.92Å
290	L	93.3	Very high	89.9	Confident	111 Å²	111	83.1 Å²	83.1	58%	0.581	42%	0.417	S	S	*	.	H	α-helix	trans	-64.6	-45.1	176.8	-177.6	67	0	0	0	111.7	Y286 I287 Y288 A293 F294	Y286-L290 VanDerWaalsContact O-CB 3.28Å; Y286-L290 WeakPolarHBondContact O-CB 3.48Å; Y286-L290 PolarHBondContact O-N 3.34Å; I287-L290 PolarHBondContact O-N 3.42Å; Y288-L290 VanDerWaalsContact C-N 3.26Å; Y288-L290 PolarHBondContact O-N 3.35Å; L290-A293 PolarHBondContact O-N 3.18Å; L290-F294 WeakPolarHBondContact O-CB 3.23Å; L290-F294 PolarHBondContact O-N 2.93Å
291	V	94.1	Very high	90.2	Very high	31 Å²	31	83.5 Å²	83.5	19%	0.188	43%	0.425	C	S	.	.	H	α-helix	trans	-62.7	-45.5	176.5	171.6	0	0	0	0	110.6	A219 A223 L277 I287 Y288 A293 F294 F295	A219-V291 HydrophobicContact CB-CB 4.18Å; A219-V291 HydrophobicContact CB-CG1 4.1Å; A223-V291 HydrophobicContact CB-CG1 4.17Å; L277-V291 HydrophobicContact CD2-CG2 4Å; I287-V291 HydrophobicContact CG1-CG2 4.36Å; I287-V291 VanDerWaalsContact O-CG2 3.31Å; I287-V291 WeakPolarHBondContact O-CG2 3.44Å; I287-V291 PolarHBondContact O-N 2.88Å; Y288-V291 PolarHBondContact O-N 3.12Å; V291-A293 PolarHBondContact O-N 3.16Å; V291-F294 PolarHBondContact O-N 3.4Å; V291-F295 HydrophobicContact CG1-CD2 4.01Å; V291-F295 HydrophobicContact CG1-CE2 3.84Å; V291-F295 VanDerWaalsContact O-CD2 3.25Å; V291-F295 WeakPolarHBondContact O-CD2 3.24Å; V291-F295 PolarHBondContact O-N 3.11Å
292	C	91.8	Very high	90.7	Very high	15 Å²	15	83.2 Å²	83.2	10%	0.101	42%	0.42	C	S	.	.	H	α-helix	trans	-58.6	-49	175	-63.3	0	0	0	0	111.7	C218 A219 Y288 P289 F294 F295 V296	C218-C292 PolarHBondContact SG-SG 3.33Å; A219-C292 WeakPolarHBondContact CA-SG 3.33Å; A219-C292 PolarHBondContact N-SG 3Å; A219-C292 VanDerWaalsContact N-SG 3.37Å; Y288-C292 PolarHBondContact O-N 3.44Å; Y288-C292 VanDerWaalsContact O-N 3.1Å; Y288-C292 PolarHBondContact O-SG 2.98Å; P289-C292 PolarHBondContact O-N 3.23Å; C292-F294 VanDerWaalsContact C-N 3.29Å; C292-F294 PolarHBondContact O-N 3.5Å; C292-F295 PolarHBondContact O-N 3.41Å; C292-V296 WeakPolarHBondContact O-CB 3.23Å; C292-V296 VanDerWaalsContact O-CG2 3.26Å; C292-V296 WeakPolarHBondContact O-CG2 3.47Å; C292-V296 PolarHBondContact O-N 2.95Å
293	A	93.3	Very high	91.5	Very high	58 Å²	58	77.3 Å²	77.3	48%	0.479	39%	0.389	S	S	.	.	H	α-helix	trans	-61	-38.2	-179.3	0	0	0	0	0	112	P289 L290 V291 A297	P289-A293 VanDerWaalsContact O-CB 3.23Å; P289-A293 WeakPolarHBondContact O-CB 3.43Å; P289-A293 PolarHBondContact O-N 2.92Å; L290-A293 PolarHBondContact O-N 3.18Å; V291-A293 PolarHBondContact O-N 3.16Å; A293-A297 WeakPolarHBondContact O-CB 3.29Å; A293-A297 PolarHBondContact O-N 2.94Å
294	F	95.5	Very high	92.1	Very high	121 Å²	121	74 Å²	74	53%	0.531	38%	0.379	S	S	.	.	H	α-helix	trans	-59.5	-53.1	176.3	173.6	-99.5	0	0	0	111.9	L290 V291 C292 A297 L298	L290-F294 WeakPolarHBondContact O-CB 3.23Å; L290-F294 PolarHBondContact O-N 2.93Å; V291-F294 PolarHBondContact O-N 3.4Å; C292-F294 VanDerWaalsContact C-N 3.29Å; C292-F294 PolarHBondContact O-N 3.5Å; F294-A297 PolarHBondContact O-N 3.28Å; F294-L298 HydrophobicContact CE1-CD1 3.96Å; F294-L298 HydrophobicContact CZ-CD1 4.08Å; F294-L298 PolarHBondContact O-N 2.99Å
295	F	94.1	Very high	92.5	Very high	17 Å²	17	68 Å²	68	8%	0.075	36%	0.359	C	S	.	.	H	α-helix	trans	-69.1	-38.3	-179	-72.3	-70.5	0	0	0	112.6	V222 A223 F226 I227 V291 C292 A297 L298	V222-F295 HydrophobicContact CG1-CB 3.48Å; V222-F295 VanDerWaalsContact CG1-CB 3.48Å; V222-F295 HydrophobicContact CG1-CD2 4.36Å; V222-F295 HydrophobicContact CG1-CG 4.06Å; A223-F295 HydrophobicContact CB-CD2 4.01Å; A223-F295 HydrophobicContact CB-CE2 3.35Å; A223-F295 HydrophobicContact CB-CZ 3.89Å; F226-F295 HydrophobicContact CB-CD1 3.79Å; F226-F295 HydrophobicContact CB-CE1 3.86Å; F226-F295 AromaticContact CD1-CD1 3.75Å; F226-F295 HydrophobicContact CD1-CD1 3.75Å; F226-F295 AromaticContact CD1-CE1 3.39Å; F226-F295 HydrophobicContact CD1-CE1 3.39Å; F226-F295 AromaticContact CD2-CD1 3.67Å; F226-F295 HydrophobicContact CD2-CD1 3.67Å; F226-F295 HydrophobicContact CD2-CE1 4.21Å; F226-F295 HydrophobicContact CE1-CD1 4.23Å; F226-F295 AromaticContact CE1-CE1 3.95Å; F226-F295 HydrophobicContact CE1-CE1 3.95Å; F226-F295 HydrophobicContact CE2-CD1 4.16Å; F226-F295 AromaticContact CG-CD1 3.45Å; F226-F295 HydrophobicContact CG-CD1 3.45Å; F226-F295 VanDerWaalsContact CG-CD1 3.45Å; F226-F295 AromaticContact CG-CE1 3.55Å; F226-F295 HydrophobicContact CG-CE1 3.55Å; F226-F295 HydrophobicContact CZ-CD1 4.42Å; I227-F295 HydrophobicContact CD1-CZ 4.23Å; I227-F295 HydrophobicContact CG1-CZ 4.33Å; V291-F295 HydrophobicContact CG1-CD2 4.01Å; V291-F295 HydrophobicContact CG1-CE2 3.84Å; V291-F295 VanDerWaalsContact O-CD2 3.25Å; V291-F295 WeakPolarHBondContact O-CD2 3.24Å; V291-F295 PolarHBondContact O-N 3.11Å; C292-F295 PolarHBondContact O-N 3.41Å; F295-A297 VanDerWaalsContact C-N 3.29Å; F295-A297 PolarHBondContact O-N 2.89Å; F295-L298 HydrophobicContact CD1-CD1 4.45Å; F295-L298 WeakPolarHBondContact O-CB 3.25Å; F295-L298 PolarHBondContact O-N 3.36Å; F295-L298 VanDerWaalsContact O-N 3.16Å
296	V	90.4	Very high	93	Very high	74 Å²	74	57.9 Å²	57.9	45%	0.448	32%	0.321	S	S	.	.	H	α-helix	trans	-63.3	-36.7	174.6	172.6	0	0	0	0	111.2	C292 L298 L299	C292-V296 WeakPolarHBondContact O-CB 3.23Å; C292-V296 VanDerWaalsContact O-CG2 3.26Å; C292-V296 WeakPolarHBondContact O-CG2 3.47Å; C292-V296 PolarHBondContact O-N 2.95Å; V296-L298 PolarHBondContact O-N 2.96Å; V296-L299 VanDerWaalsContact O-CB 3.23Å; V296-L299 WeakPolarHBondContact O-CB 3.47Å; V296-L299 PolarHBondContact O-N 2.97Å; V296-L299 VanDerWaalsContact O-N 3.13Å
297	A	94.3	Very high	93.2	Very high	69 Å²	69	55.3 Å²	55.3	57%	0.57	31%	0.31	S	S	*	.	H	α-helix	trans	-66.2	-22.6	176.8	0	0	0	0	0	113.5	A293 F294 F295 P300	A293-A297 WeakPolarHBondContact O-CB 3.29Å; A293-A297 PolarHBondContact O-N 2.94Å; F294-A297 PolarHBondContact O-N 3.28Å; F295-A297 VanDerWaalsContact C-N 3.29Å; F295-A297 PolarHBondContact O-N 2.89Å; A297-P300 WeakPolarHBondContact O-CD 3.15Å
298	L	94.2	Very high	93.1	Very high	50 Å²	50	62.7 Å²	62.7	26%	0.262	34%	0.336	S	S	.	.	H	α-helix	trans	-78.8	-21.5	174.3	-63.4	176.5	0	0	0	112.8	F226 F294 F295 V296 V301 W302	F226-L298 HydrophobicContact CE2-CD1 4.06Å; F226-L298 HydrophobicContact CZ-CD1 3.77Å; F294-L298 HydrophobicContact CE1-CD1 3.96Å; F294-L298 HydrophobicContact CZ-CD1 4.08Å; F294-L298 PolarHBondContact O-N 2.99Å; F295-L298 HydrophobicContact CD1-CD1 4.45Å; F295-L298 WeakPolarHBondContact O-CB 3.25Å; F295-L298 PolarHBondContact O-N 3.36Å; F295-L298 VanDerWaalsContact O-N 3.16Å; V296-L298 PolarHBondContact O-N 2.96Å; L298-V301 WeakPolarHBondContact O-CB 3.45Å; L298-V301 PolarHBondContact O-N 3.14Å; L298-W302 PolarHBondContact O-N 3.27Å
299	L	93.7	Very high	92.5	Very high	46 Å²	46	62.8 Å²	62.8	24%	0.241	34%	0.338	C	S	.	.	H	α-helix	trans	-55.3	-46.3	-175	-172.4	155.7	0	0	0	113.5	T188 V189 V296 V301 W302 V303	T188-L299 HydrophobicContact CG2-CD1 4.23Å; V189-L299 HydrophobicContact CG2-CD1 3.61Å; V296-L299 VanDerWaalsContact O-CB 3.23Å; V296-L299 WeakPolarHBondContact O-CB 3.47Å; V296-L299 PolarHBondContact O-N 2.97Å; V296-L299 VanDerWaalsContact O-N 3.13Å; L299-V301 PolarHBondContact O-N 3.1Å; L299-W302 PolarHBondContact O-N 3.26Å; L299-V303 HydrophobicContact CD2-CG2 3.71Å; L299-V303 HydrophobicContact CG-CG2 4.44Å; L299-V303 WeakPolarHBondContact O-CG2 3.03Å; L299-V303 PolarHBondContact O-N 3.36Å
300	P	94.6	Very high	92.1	Very high	76 Å²	76	65 Å²	65	49%	0.494	35%	0.352	S	S	.	.	H	α-helix	trans	-58.7	-36.1	177.5	-24.2	34.7	0	0	0	113.2	A297 V303 V304	A297-P300 WeakPolarHBondContact O-CD 3.15Å; P300-V303 PolarHBondContact O-N 3.07Å; P300-V304 VanDerWaalsContact O-CG2 3.3Å; P300-V304 WeakPolarHBondContact O-CG2 3.25Å; P300-V304 PolarHBondContact O-N 3.03Å
301	V	94.5	Very high	91.3	Very high	90 Å²	90	62.8 Å²	62.8	55%	0.545	35%	0.35	S	S	.	.	H	α-helix	trans	-64.7	-47.7	179	-178.9	0	0	0	0	110	L298 L299 V304 L305	L298-V301 WeakPolarHBondContact O-CB 3.45Å; L298-V301 PolarHBondContact O-N 3.14Å; L299-V301 PolarHBondContact O-N 3.1Å; V301-V304 PolarHBondContact O-N 2.81Å; V301-L305 WeakPolarHBondContact O-CB 3.3Å; V301-L305 PolarHBondContact O-N 3.29Å
302	W	94.2	Very high	90.8	Very high	47 Å²	47	61.3 Å²	61.3	18%	0.178	34%	0.341	C	S	.	.	H	α-helix	trans	-67.1	-37.7	178.9	-62.4	119.2	0	0	0	112.5	A181 Q184 V185 F226 L298 L299 V304 L305 A306	A181-W302 HydrophobicContact CB-CE3 3.74Å; A181-W302 HydrophobicContact CB-CZ3 4.36Å; Q184-W302 HydrophobicContact CB-CB 4.29Å; Q184-W302 HydrophobicContact CB-CD2 3.69Å; Q184-W302 HydrophobicContact CB-CE3 4.16Å; Q184-W302 HydrophobicContact CB-CG 3.75Å; Q184-W302 HydrophobicContact CB-CZ2 4.49Å; Q184-W302 HydrophobicContact CG-CD2 4.02Å; Q184-W302 HydrophobicContact CG-CE3 4.21Å; Q184-W302 HydrophobicContact CG-CH2 4.18Å; Q184-W302 HydrophobicContact CG-CZ2 4.01Å; Q184-W302 HydrophobicContact CG-CZ3 4.28Å; V185-W302 HydrophobicContact CG2-CB 3.48Å; V185-W302 VanDerWaalsContact CG2-CB 3.48Å; F226-W302 AromaticContact CE2-NE1 3.35Å; F226-W302 HydrophobicContact CZ-CZ2 4.01Å; F226-W302 AromaticContact CZ-NE1 3.54Å; L298-W302 PolarHBondContact O-N 3.27Å; L299-W302 PolarHBondContact O-N 3.26Å; W302-V304 PolarHBondContact O-N 2.97Å; W302-L305 HydrophobicContact CE3-CD2 4Å; W302-L305 HydrophobicContact CZ3-CD2 3.95Å; W302-L305 PolarHBondContact O-N 3.49Å; W302-A306 VanDerWaalsContact O-CB 3.29Å; W302-A306 WeakPolarHBondContact O-CB 3.5Å; W302-A306 PolarHBondContact O-N 3.05Å
303	V	94.1	Very high	90.6	Very high	23 Å²	23	67.5 Å²	67.5	14%	0.139	36%	0.362	C	S	.	.	H	α-helix	trans	-60.7	-46.2	174.1	168.9	0	0	0	0	111.1	V185 L299 P300 L305 A306 R307 L316	V185-V303 HydrophobicContact CG1-CG2 3.95Å; V185-V303 HydrophobicContact CG2-CB 4.42Å; V185-V303 HydrophobicContact CG2-CG2 3.68Å; L299-V303 HydrophobicContact CD2-CG2 3.71Å; L299-V303 HydrophobicContact CG-CG2 4.44Å; L299-V303 WeakPolarHBondContact O-CG2 3.03Å; L299-V303 PolarHBondContact O-N 3.36Å; P300-V303 PolarHBondContact O-N 3.07Å; V303-L305 VanDerWaalsContact C-N 3.29Å; V303-L305 PolarHBondContact O-N 3.17Å; V303-A306 PolarHBondContact O-N 3.36Å; V303-R307 VanDerWaalsContact O-CG 3.27Å; V303-R307 WeakPolarHBondContact O-CG 3.28Å; V303-R307 PolarHBondContact O-N 3.41Å; V303-L316 HydrophobicContact CG1-CD2 4.39Å
304	V	94.5	Very high	90.1	Very high	80 Å²	80	71.4 Å²	71.4	49%	0.485	37%	0.371	S	S	.	.	H	α-helix	trans	-62.3	-40.9	177.5	170.4	0	0	0	0	110.7	P300 V301 W302	P300-V304 VanDerWaalsContact O-CG2 3.3Å; P300-V304 WeakPolarHBondContact O-CG2 3.25Å; P300-V304 PolarHBondContact O-N 3.03Å; V301-V304 PolarHBondContact O-N 2.81Å; W302-V304 PolarHBondContact O-N 2.97Å
305	L	92.2	Very high	89.5	Confident	41 Å²	41	66.4 Å²	66.4	22%	0.215	35%	0.35	C	S	.	.	H	α-helix	trans	-69.8	-42.1	-179.1	-168.6	55	0	0	0	112.5	T177 A181 V301 W302 V303 R307 R308	T177-L305 HydrophobicContact CG2-CD1 3.57Å; T177-L305 HydrophobicContact CG2-CD2 3.54Å; T177-L305 HydrophobicContact CG2-CG 3.64Å; A181-L305 HydrophobicContact CB-CB 3.75Å; A181-L305 HydrophobicContact CB-CD2 3.97Å; A181-L305 HydrophobicContact CB-CG 3.76Å; V301-L305 WeakPolarHBondContact O-CB 3.3Å; V301-L305 PolarHBondContact O-N 3.29Å; W302-L305 HydrophobicContact CE3-CD2 4Å; W302-L305 HydrophobicContact CZ3-CD2 3.95Å; W302-L305 PolarHBondContact O-N 3.49Å; V303-L305 VanDerWaalsContact C-N 3.29Å; V303-L305 PolarHBondContact O-N 3.17Å; L305-R307 VanDerWaalsContact C-N 3.32Å; L305-R307 PolarHBondContact O-N 3.03Å; L305-R308 WeakPolarHBondContact O-CB 3.49Å; L305-R308 PolarHBondContact O-N 3.25Å
306	A	91.2	Very high	89.2	Confident	0 Å²	0	66.1 Å²	66.1	0%	0	35%	0.349	C	S	.	.	H	α-helix	trans	-65.2	-33.2	176.5	0	0	0	0	0	112.3	A181 L182 W302 V303 R308 T312 L316	A181-A306 HydrophobicContact CB-CB 3.99Å; L182-A306 HydrophobicContact CB-CB 4.27Å; W302-A306 VanDerWaalsContact O-CB 3.29Å; W302-A306 WeakPolarHBondContact O-CB 3.5Å; W302-A306 PolarHBondContact O-N 3.05Å; V303-A306 PolarHBondContact O-N 3.36Å; A306-R308 VanDerWaalsContact C-N 3.25Å; A306-R308 PolarHBondContact O-N 3.45Å; A306-T312 WeakPolarHBondContact O-CB 3.18Å; A306-T312 PolarHBondContact O-OG1 3.23Å; A306-L316 HydrophobicContact CB-CD2 4.23Å
307	R	92.2	Very high	89.1	Confident	124 Å²	124	69 Å²	69	47%	0.468	35%	0.353	S	S	.	.	T	Hydrogen-bonded Turn	trans	-69.8	-17.7	177.1	-74.9	178.7	-171.1	178.9	5.2	114.3	V303 L305 L316 Y317	V303-R307 VanDerWaalsContact O-CG 3.27Å; V303-R307 WeakPolarHBondContact O-CG 3.28Å; V303-R307 PolarHBondContact O-N 3.41Å; L305-R307 VanDerWaalsContact C-N 3.32Å; L305-R307 PolarHBondContact O-N 3.03Å; R307-L316 HydrophobicContact CG-CD2 3.61Å; R307-Y317 PolarHBondContact NE-OH 3.3Å
308	R	88.3	Confident	88.6	Confident	186 Å²	186	69 Å²	69	70%	0.702	35%	0.349	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.1	-25.6	-177.3	-73	-179.1	178.4	-179.9	-0.4	113.5	L305 A306	L305-R308 WeakPolarHBondContact O-CB 3.49Å; L305-R308 PolarHBondContact O-N 3.25Å; A306-R308 VanDerWaalsContact C-N 3.25Å; A306-R308 PolarHBondContact O-N 3.45Å
309	S	81.5	Confident	88	Confident	11 Å²	11	67.2 Å²	67.2	8%	0.077	34%	0.342	C	S	.	.	S	Bend	trans	-98.3	126.3	176	172.9	0	0	0	0	109.7	A311 T312 R313	S309-A311 VanDerWaalsContact C-N 3.3Å; S309-A311 PolarHBondContact O-N 3.01Å; S309-T312 VanDerWaalsContact CB-OG1 3.26Å; S309-T312 WeakPolarHBondContact CB-OG1 3.34Å; S309-T312 PolarHBondContact O-N 3.18Å; S309-T312 PolarHBondContact O-OG1 3.35Å; S309-R313 WeakPolarHBondContact O-CB 3.36Å; S309-R313 PolarHBondContact O-N 3.35Å
310	P	82.5	Confident	87.8	Confident	96 Å²	96	67.8 Å²	67.8	62%	0.623	34%	0.341	S	S	*	.	H	α-helix	trans	-55.4	-43	-178.9	-27.7	35	0	0	0	113.4	T312 R313 E314	P310-T312 PolarHBondContact O-N 2.99Å; P310-R313 WeakPolarHBondContact O-CB 3.34Å; P310-R313 PolarHBondContact O-N 3.49Å; P310-E314 PolarHBondContact O-N 2.71Å
311	A	76.5	Confident	87.6	Confident	63 Å²	63	69.8 Å²	69.8	52%	0.521	34%	0.344	S	S	.	.	H	α-helix	trans	-61.8	-40.7	-179.5	0	0	0	0	0	112.6	S309 V315	S309-A311 VanDerWaalsContact C-N 3.3Å; S309-A311 PolarHBondContact O-N 3.01Å; A311-V315 WeakPolarHBondContact O-CG2 3.24Å
312	T	83.9	Confident	87.3	Confident	1 Å²	1	65.6 Å²	65.6	1%	0.006	32%	0.319	C	S	.	.	H	α-helix	trans	-81.3	-25.3	179.4	50.8	0	0	0	0	112.5	G178 N179 L182 A306 S309 P310 L316	G178-T312 WeakPolarHBondContact O-CG2 3.32Å; N179-T312 HydrophobicContact CB-CG2 4.35Å; L182-T312 HydrophobicContact CB-CG2 4.24Å; L182-T312 HydrophobicContact CD2-CG2 4.09Å; A306-T312 WeakPolarHBondContact O-CB 3.18Å; A306-T312 PolarHBondContact O-OG1 3.23Å; S309-T312 VanDerWaalsContact CB-OG1 3.26Å; S309-T312 WeakPolarHBondContact CB-OG1 3.34Å; S309-T312 PolarHBondContact O-N 3.18Å; S309-T312 PolarHBondContact O-OG1 3.35Å; P310-T312 PolarHBondContact O-N 2.99Å; T312-L316 VanDerWaalsContact O-CB 3.26Å; T312-L316 WeakPolarHBondContact O-CB 3.45Å; T312-L316 PolarHBondContact O-N 3.45Å
313	R	87	Confident	87.1	Confident	144 Å²	144	63.8 Å²	63.8	54%	0.543	31%	0.313	S	S	.	.	H	α-helix	trans	-62	-45.3	174.9	179.7	-176.4	167.4	179.1	-2.9	111.2	S309 P310 L316 Y317	S309-R313 WeakPolarHBondContact O-CB 3.36Å; S309-R313 PolarHBondContact O-N 3.35Å; P310-R313 WeakPolarHBondContact O-CB 3.34Å; P310-R313 PolarHBondContact O-N 3.49Å; R313-L316 PolarHBondContact O-N 2.92Å; R313-Y317 HydrophobicContact CG-CD2 4.07Å; R313-Y317 HydrophobicContact CG-CE2 3.73Å; R313-Y317 WeakPolarHBondContact O-CD2 3.18Å; R313-Y317 PolarHBondContact O-N 3.39Å
314	E	83.3	Confident	87.1	Confident	141 Å²	141	65.7 Å²	65.7	66%	0.659	32%	0.322	S	S	*	.	H	α-helix	trans	-60.5	-47.6	179	-178.3	173.4	-176.4	0	0	111.6	P310 L316 Y317 S318	P310-E314 PolarHBondContact O-N 2.71Å; E314-L316 VanDerWaalsContact C-N 3.33Å; E314-L316 PolarHBondContact O-N 2.92Å; E314-Y317 PolarHBondContact O-N 2.97Å; E314-Y317 VanDerWaalsContact O-N 3.15Å; E314-S318 PolarHBondContact O-N 3.48Å; E314-S318 PolarHBondContact O-OG 2.89Å
315	V	82.3	Confident	87	Confident	16 Å²	16	65.1 Å²	65.1	10%	0.097	32%	0.315	C	S	.	.	H	α-helix	trans	-66.9	-35.8	179.8	-175.7	0	0	0	0	111.5	R156 L182 A311 Y317 S318 G319	R156-V315 VanDerWaalsContact CZ-CG2 3.43Å; R156-V315 VanDerWaalsContact NH2-CG1 3.3Å; L182-V315 HydrophobicContact CD2-CB 3.82Å; L182-V315 HydrophobicContact CD2-CG1 3.77Å; A311-V315 WeakPolarHBondContact O-CG2 3.24Å; V315-Y317 PolarHBondContact O-N 3.35Å; V315-S318 PolarHBondContact O-N 2.64Å; V315-G319 WeakPolarHBondContact O-CA 3.17Å; V315-G319 PolarHBondContact O-N 2.91Å
316	L	88.4	Confident	87.1	Confident	10 Å²	10	63.2 Å²	63.2	5%	0.052	31%	0.305	C	S	.	.	H	α-helix	trans	-61.3	-25	176.2	-176.9	64.1	0	0	0	112.8	L182 V185 V303 A306 R307 T312 R313 E314 W320	L182-L316 HydrophobicContact CD1-CB 3.91Å; L182-L316 HydrophobicContact CD1-CD1 3.99Å; V185-L316 HydrophobicContact CB-CD1 4.48Å; V185-L316 HydrophobicContact CG1-CD1 3.92Å; V303-L316 HydrophobicContact CG1-CD2 4.39Å; A306-L316 HydrophobicContact CB-CD2 4.23Å; R307-L316 HydrophobicContact CG-CD2 3.61Å; T312-L316 VanDerWaalsContact O-CB 3.26Å; T312-L316 WeakPolarHBondContact O-CB 3.45Å; T312-L316 PolarHBondContact O-N 3.45Å; R313-L316 PolarHBondContact O-N 2.92Å; E314-L316 VanDerWaalsContact C-N 3.33Å; E314-L316 PolarHBondContact O-N 2.92Å; L316-W320 HydrophobicContact CD1-CZ2 4.09Å; L316-W320 PolarHBondContact O-NE1 3.4Å
317	Y	86.8	Confident	87.2	Confident	134 Å²	134	63.6 Å²	63.6	53%	0.525	31%	0.307	S	S	.	.	H	α-helix	trans	-96.7	-32.1	178.2	-71.1	-65.1	0	0	0	113.4	R307 R313 E314 V315	R307-Y317 PolarHBondContact NE-OH 3.3Å; R313-Y317 HydrophobicContact CG-CD2 4.07Å; R313-Y317 HydrophobicContact CG-CE2 3.73Å; R313-Y317 WeakPolarHBondContact O-CD2 3.18Å; R313-Y317 PolarHBondContact O-N 3.39Å; E314-Y317 PolarHBondContact O-N 2.97Å; E314-Y317 VanDerWaalsContact O-N 3.15Å; V315-Y317 PolarHBondContact O-N 3.35Å
318	S	84.7	Confident	87.4	Confident	70 Å²	70	59.7 Å²	59.7	49%	0.49	30%	0.301	S	S	.	.	H	α-helix	trans	-105.3	-27.2	-172.8	57.8	0	0	0	0	114.8	E314 V315 W320	E314-S318 PolarHBondContact O-N 3.48Å; E314-S318 PolarHBondContact O-OG 2.89Å; V315-S318 PolarHBondContact O-N 2.64Å; S318-W320 VanDerWaalsContact C-N 3.29Å; S318-W320 PolarHBondContact O-N 2.92Å; S318-W320 VanDerWaalsContact O-N 3.13Å
319	G	81.8	Confident	87.7	Confident	12 Å²	12	53.1 Å²	53.1	12%	0.124	28%	0.28	C	S	.	.	T	Hydrogen-bonded Turn	trans	-82.1	15.7	-166.6	0	0	0	0	0	116.6	V315 V323	V315-G319 WeakPolarHBondContact O-CA 3.17Å; V315-G319 PolarHBondContact O-N 2.91Å; G319-V323 WeakPolarHBondContact O-CG2 3.31Å
320	W	89.3	Confident	88.4	Confident	58 Å²	58	52.7 Å²	52.7	22%	0.22	28%	0.276	C	S	.	.	H	α-helix	trans	-84.5	-38.2	-175.6	-67.7	101.2	0	0	0	113.7	V185 Q186 V189 V190 L316 S318 V323 I324	V185-W320 HydrophobicContact CG1-CH2 3.87Å; V185-W320 HydrophobicContact CG1-CZ2 4.06Å; Q186-W320 HydrophobicContact CG-CH2 4.22Å; Q186-W320 HydrophobicContact CG-CZ3 4.28Å; V189-W320 HydrophobicContact CB-CH2 3.96Å; V189-W320 HydrophobicContact CB-CZ3 3.81Å; V189-W320 HydrophobicContact CG1-CH2 4.11Å; V189-W320 HydrophobicContact CG1-CZ3 3.67Å; V189-W320 HydrophobicContact CG2-CH2 3.96Å; V189-W320 HydrophobicContact CG2-CZ3 4.32Å; V190-W320 HydrophobicContact CG2-CZ3 4.42Å; L316-W320 HydrophobicContact CD1-CZ2 4.09Å; L316-W320 PolarHBondContact O-NE1 3.4Å; S318-W320 VanDerWaalsContact C-N 3.29Å; S318-W320 PolarHBondContact O-N 2.92Å; S318-W320 VanDerWaalsContact O-N 3.13Å; W320-V323 PolarHBondContact O-N 2.9Å; W320-I324 HydrophobicContact CB-CD1 4.07Å; W320-I324 HydrophobicContact CE3-CD1 4.36Å; W320-I324 WeakPolarHBondContact O-CB 3.11Å; W320-I324 VanDerWaalsContact O-CG1 3.31Å; W320-I324 WeakPolarHBondContact O-CG1 3.22Å; W320-I324 PolarHBondContact O-N 3.19Å
321	E	90.2	Very high	89	Confident	119 Å²	119	48.1 Å²	48.1	56%	0.556	25%	0.247	S	C	*	.	H	α-helix	trans	-54.6	-54.1	-176.3	-179	179.5	170.8	0	0	113.1	V323 I325	E321-V323 VanDerWaalsContact C-N 3.33Å; E321-V323 PolarHBondContact O-N 2.99Å; E321-I325 HydrophobicContact CG-CD1 3.67Å; E321-I325 WeakPolarHBondContact O-CB 3.2Å; E321-I325 VanDerWaalsContact O-CG1 3.31Å; E321-I325 WeakPolarHBondContact O-CG1 3.42Å; E321-I325 PolarHBondContact O-N 3.45Å; E321-I325 VanDerWaalsContact O-N 3.12Å
322	P	88.6	Confident	89.9	Confident	2 Å²	2	48 Å²	48	1%	0.013	24%	0.239	C	C	.	.	H	α-helix	trans	-65.2	-37.4	-178.9	24.7	-33.9	0	0	0	112.2	A326 N476 F477 P480 Y481	P322-A326 WeakPolarHBondContact O-CB 3.35Å; P322-A326 PolarHBondContact O-N 3.28Å; P322-N476 WeakPolarHBondContact CG-O 3.31Å; P322-F477 HydrophobicContact CB-CD1 4.09Å; P322-F477 HydrophobicContact CG-CD1 3.88Å; P322-F477 HydrophobicContact CG-CE1 4.28Å; P322-P480 HydrophobicContact CB-CB 3.97Å; P322-P480 HydrophobicContact CB-CG 4.08Å; P322-Y481 HydrophobicContact CB-CE1 4.34Å; P322-Y481 HydrophobicContact CB-CE2 4.41Å
323	V	90.3	Very high	90.4	Very high	9 Å²	9	47.9 Å²	47.9	6%	0.055	24%	0.239	C	C	.	.	H	α-helix	trans	-70.6	-42.8	-177.2	-176.3	0	0	0	0	111.8	L145 L149 V190 G319 W320 E321 M327	L145-V323 HydrophobicContact CD1-CG1 3.84Å; L149-V323 HydrophobicContact CD2-CG1 4.39Å; V190-V323 HydrophobicContact CB-CG1 4.48Å; V190-V323 HydrophobicContact CG1-CG1 4.29Å; V190-V323 HydrophobicContact CG2-CG1 3.62Å; G319-V323 WeakPolarHBondContact O-CG2 3.31Å; W320-V323 PolarHBondContact O-N 2.9Å; E321-V323 VanDerWaalsContact C-N 3.33Å; E321-V323 PolarHBondContact O-N 2.99Å; V323-M327 WeakPolarHBondContact O-CB 3.42Å; V323-M327 PolarHBondContact O-N 3.28Å
324	I	93.1	Very high	90.9	Very high	63 Å²	63	41 Å²	41	32%	0.323	21%	0.213	S	C	.	.	H	α-helix	trans	-69.9	-44.9	-179.3	-67.5	171.8	0	0	0	110.8	L193 W320 M327 A328	L193-I324 HydrophobicContact CD1-CD1 4.15Å; L193-I324 HydrophobicContact CD1-CG1 4.04Å; W320-I324 HydrophobicContact CB-CD1 4.07Å; W320-I324 HydrophobicContact CE3-CD1 4.36Å; W320-I324 WeakPolarHBondContact O-CB 3.11Å; W320-I324 VanDerWaalsContact O-CG1 3.31Å; W320-I324 WeakPolarHBondContact O-CG1 3.22Å; W320-I324 PolarHBondContact O-N 3.19Å; I324-M327 PolarHBondContact O-N 3.05Å; I324-A328 PolarHBondContact O-N 3Å
325	I	93.4	Very high	91.4	Very high	68 Å²	68	36.2 Å²	36.2	35%	0.349	19%	0.191	S	C	.	.	H	α-helix	trans	-65.9	-42.9	178.9	-67.4	171.1	0	0	0	110.3	E321 M327 A328 I329 Y481	E321-I325 HydrophobicContact CG-CD1 3.67Å; E321-I325 WeakPolarHBondContact O-CB 3.2Å; E321-I325 VanDerWaalsContact O-CG1 3.31Å; E321-I325 WeakPolarHBondContact O-CG1 3.42Å; E321-I325 PolarHBondContact O-N 3.45Å; E321-I325 VanDerWaalsContact O-N 3.12Å; I325-M327 PolarHBondContact O-N 2.84Å; I325-A328 PolarHBondContact O-N 2.62Å; I325-I329 HydrophobicContact CG2-CD1 3.92Å; I325-I329 HydrophobicContact CG2-CG1 4.48Å; I325-I329 WeakPolarHBondContact O-CG1 3.01Å; I325-I329 PolarHBondContact O-N 2.88Å; I325-Y481 HydrophobicContact CB-CE1 3.8Å; I325-Y481 HydrophobicContact CD1-CE1 4.26Å; I325-Y481 HydrophobicContact CG2-CD1 4.04Å; I325-Y481 HydrophobicContact CG2-CE1 3.58Å
326	A	93.7	Very high	92.1	Very high	0 Å²	0	37.9 Å²	37.9	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-58.2	-47.8	175.1	0	0	0	0	0	111.6	N148 P322 A328 I329 S330 P480 A484	N148-A326 WeakPolarHBondContact ND2-CB 3.42Å; P322-A326 WeakPolarHBondContact O-CB 3.35Å; P322-A326 PolarHBondContact O-N 3.28Å; A326-A328 VanDerWaalsContact C-N 3.31Å; A326-A328 PolarHBondContact O-N 2.94Å; A326-I329 PolarHBondContact O-N 3.48Å; A326-S330 PolarHBondContact O-N 3.49Å; A326-S330 PolarHBondContact O-OG 3.44Å; A326-P480 HydrophobicContact CB-CB 3.86Å; A326-P480 WeakPolarHBondContact CB-O 3.33Å; A326-A484 HydrophobicContact CB-CB 3.78Å; A326-A484 WeakPolarHBondContact O-CB 3.27Å
327	M	94.5	Very high	92.4	Very high	9 Å²	9	37.4 Å²	37.4	4%	0.044	20%	0.197	C	C	.	.	H	α-helix	trans	-57.1	-44.3	175.6	177.7	-81.8	-63.3	0	0	111.7	A141 V190 L193 A194 A197 V323 I324 I325 I329 S330 S331	A141-M327 HydrophobicContact CB-CG 4.41Å; V190-M327 HydrophobicContact CG1-CB 3.75Å; V190-M327 HydrophobicContact CG1-CG 3.68Å; L193-M327 HydrophobicContact CB-CE 3.5Å; L193-M327 VanDerWaalsContact CB-CE 3.5Å; A194-M327 VanDerWaalsContact CA-SD 3.57Å; A194-M327 HydrophobicContact CB-CG 3.93Å; A194-M327 HydrophobicContact CB-SD 3.9Å; A197-M327 HydrophobicContact CB-SD 4.19Å; V323-M327 WeakPolarHBondContact O-CB 3.42Å; V323-M327 PolarHBondContact O-N 3.28Å; I324-M327 PolarHBondContact O-N 3.05Å; I325-M327 PolarHBondContact O-N 2.84Å; M327-I329 PolarHBondContact O-N 3.14Å; M327-S330 PolarHBondContact O-N 3.47Å; M327-S331 WeakPolarHBondContact O-CB 3.28Å; M327-S331 PolarHBondContact O-N 3.22Å; M327-S331 PolarHBondContact O-OG 2.82Å; M327-S331 VanDerWaalsContact O-OG 3.1Å
328	A	94.6	Very high	92.8	Very high	42 Å²	42	31 Å²	31	35%	0.347	17%	0.172	S	C	.	.	H	α-helix	trans	-62	-41.2	178	0	0	0	0	0	112.7	I324 I325 A326 S331 V332	I324-A328 PolarHBondContact O-N 3Å; I325-A328 PolarHBondContact O-N 2.62Å; A326-A328 VanDerWaalsContact C-N 3.31Å; A326-A328 PolarHBondContact O-N 2.94Å; A328-S331 PolarHBondContact O-N 3.35Å; A328-V332 PolarHBondContact O-N 3.37Å
329	I	95.6	Very high	93.2	Very high	48 Å²	48	31.7 Å²	31.7	25%	0.246	17%	0.166	C	C	.	.	H	α-helix	trans	-65.2	-47.4	176	-65.8	167.6	0	0	0	110.4	I325 A326 M327 S331 V332 G333 A484 L488	I325-I329 HydrophobicContact CG2-CD1 3.92Å; I325-I329 HydrophobicContact CG2-CG1 4.48Å; I325-I329 WeakPolarHBondContact O-CG1 3.01Å; I325-I329 PolarHBondContact O-N 2.88Å; A326-I329 PolarHBondContact O-N 3.48Å; M327-I329 PolarHBondContact O-N 3.14Å; I329-S331 VanDerWaalsContact C-N 3.28Å; I329-S331 PolarHBondContact O-N 2.71Å; I329-V332 WeakPolarHBondContact O-CB 3.41Å; I329-V332 PolarHBondContact O-N 2.83Å; I329-G333 PolarHBondContact O-N 3.33Å; I329-A484 HydrophobicContact CB-CB 3.93Å; I329-A484 HydrophobicContact CG2-CB 3.97Å; I329-A484 WeakPolarHBondContact CG2-O 3.44Å; I329-L488 HydrophobicContact CG2-CB 4.11Å; I329-L488 HydrophobicContact CG2-CD2 4.04Å
330	S	95.2	Very high	93.7	Very high	1 Å²	1	32 Å²	32	1%	0.007	17%	0.165	C	C	.	.	H	α-helix	trans	-61.5	-36.1	176.9	-64.2	0	0	0	0	111.9	A326 M327 V332 G333 G334 A484 D487	A326-S330 PolarHBondContact O-N 3.49Å; A326-S330 PolarHBondContact O-OG 3.44Å; M327-S330 PolarHBondContact O-N 3.47Å; S330-V332 VanDerWaalsContact C-N 3.28Å; S330-V332 PolarHBondContact O-N 3.43Å; S330-G333 CarbonylContact O-C 3.51Å; S330-G333 WeakPolarHBondContact O-CA 3.27Å; S330-G333 PolarHBondContact O-N 3.25Å; S330-G334 PolarHBondContact O-N 3.34Å; S330-A484 WeakPolarHBondContact OG-CA 3.41Å; S330-A484 WeakPolarHBondContact OG-CB 3.26Å; S330-D487 PolarHBondContact OG-OD2 3.41Å
331	S	95.4	Very high	93.8	Very high	0 Å²	0	29.7 Å²	29.7	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-62.8	-30.8	173.9	-68.8	0	0	0	0	113.2	A141 F201 M327 A328 I329 G334 L335	A141-S331 WeakPolarHBondContact CB-OG 3.37Å; F201-S331 VanDerWaalsContact CE2-CB 3.48Å; M327-S331 WeakPolarHBondContact O-CB 3.28Å; M327-S331 PolarHBondContact O-N 3.22Å; M327-S331 PolarHBondContact O-OG 2.82Å; M327-S331 VanDerWaalsContact O-OG 3.1Å; A328-S331 PolarHBondContact O-N 3.35Å; I329-S331 VanDerWaalsContact C-N 3.28Å; I329-S331 PolarHBondContact O-N 2.71Å; S331-G334 PolarHBondContact O-N 3.36Å; S331-L335 PolarHBondContact O-N 3.18Å
332	V	95.8	Very high	93.7	Very high	60 Å²	60	26.9 Å²	26.9	36%	0.364	15%	0.151	S	C	.	.	H	α-helix	trans	-66.8	-39.9	170.7	-179.7	0	0	0	0	110.4	F201 A328 I329 S330 G334 L335 I336 L488	F201-V332 HydrophobicContact CE2-CG2 4.02Å; F201-V332 HydrophobicContact CZ-CG2 4.04Å; A328-V332 PolarHBondContact O-N 3.37Å; I329-V332 WeakPolarHBondContact O-CB 3.41Å; I329-V332 PolarHBondContact O-N 2.83Å; S330-V332 VanDerWaalsContact C-N 3.28Å; S330-V332 PolarHBondContact O-N 3.43Å; V332-G334 VanDerWaalsContact C-N 3.28Å; V332-G334 PolarHBondContact O-N 3.1Å; V332-L335 WeakPolarHBondContact O-CB 3.28Å; V332-L335 PolarHBondContact O-N 3.37Å; V332-I336 PolarHBondContact O-N 2.87Å; V332-L488 HydrophobicContact CB-CD1 4.14Å; V332-L488 HydrophobicContact CG1-CD1 3.76Å
333	G	95.3	Very high	93.7	Very high	0 Å²	0	29.3 Å²	29.3	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-59.1	-41	170.2	0	0	0	0	0	112	I329 S330 L335 I336 L337 T491	I329-G333 PolarHBondContact O-N 3.33Å; S330-G333 CarbonylContact O-C 3.51Å; S330-G333 WeakPolarHBondContact O-CA 3.27Å; S330-G333 PolarHBondContact O-N 3.25Å; G333-L335 VanDerWaalsContact C-N 3.32Å; G333-L335 PolarHBondContact O-N 2.91Å; G333-I336 WeakPolarHBondContact O-CB 3.41Å; G333-I336 PolarHBondContact O-N 3.37Å; G333-I336 VanDerWaalsContact O-N 3.15Å; G333-L337 PolarHBondContact O-N 3.02Å; G333-T491 WeakPolarHBondContact O-CG2 3.27Å
334	G	95.8	Very high	93.4	Very high	0 Å²	0	34.1 Å²	34.1	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-58.3	-38.8	172.9	0	0	0	0	0	114.1	I137 S330 S331 V332 I336 L337 D338	I137-G334 WeakPolarHBondContact CA-O 3.4Å; S330-G334 PolarHBondContact O-N 3.34Å; S331-G334 PolarHBondContact O-N 3.36Å; V332-G334 VanDerWaalsContact C-N 3.28Å; V332-G334 PolarHBondContact O-N 3.1Å; G334-I336 VanDerWaalsContact C-N 3.32Å; G334-I336 PolarHBondContact O-N 2.99Å; G334-L337 WeakPolarHBondContact O-CB 3.25Å; G334-L337 PolarHBondContact O-N 2.96Å; G334-D338 PolarHBondContact O-N 2.88Å
335	L	95.5	Very high	93	Very high	39 Å²	39	34.4 Å²	34.4	20%	0.204	20%	0.198	C	C	.	.	H	α-helix	trans	-64.4	-37	175.6	-177.5	61.8	0	0	0	112.2	I137 F201 P205 S331 V332 G333 K339	I137-L335 HydrophobicContact CD1-CD1 3.93Å; F201-L335 HydrophobicContact CB-CD1 4.29Å; F201-L335 HydrophobicContact CB-CD2 4.38Å; F201-L335 WeakPolarHBondContact O-CD1 3.45Å; P205-L335 HydrophobicContact CG-CD1 4.06Å; S331-L335 PolarHBondContact O-N 3.18Å; V332-L335 WeakPolarHBondContact O-CB 3.28Å; V332-L335 PolarHBondContact O-N 3.37Å; G333-L335 VanDerWaalsContact C-N 3.32Å; G333-L335 PolarHBondContact O-N 2.91Å; L335-K339 WeakPolarHBondContact O-CG 3.28Å; L335-K339 PolarHBondContact O-N 3.43Å
336	I	95.7	Very high	92.7	Very high	51 Å²	51	32.1 Å²	32.1	26%	0.262	19%	0.185	S	C	.	.	H	α-helix	trans	-66.1	-43	173.9	-59.1	172.8	0	0	0	110	V332 G333 G334 K339 T340 L488 T491 A495	V332-I336 PolarHBondContact O-N 2.87Å; G333-I336 WeakPolarHBondContact O-CB 3.41Å; G333-I336 PolarHBondContact O-N 3.37Å; G333-I336 VanDerWaalsContact O-N 3.15Å; G334-I336 VanDerWaalsContact C-N 3.32Å; G334-I336 PolarHBondContact O-N 2.99Å; I336-K339 PolarHBondContact O-N 3.19Å; I336-T340 HydrophobicContact CG2-CG2 4.35Å; I336-T340 WeakPolarHBondContact O-CB 3.29Å; I336-T340 VanDerWaalsContact O-CG2 3.29Å; I336-T340 WeakPolarHBondContact O-CG2 3.29Å; I336-T340 PolarHBondContact O-N 3.17Å; I336-T340 VanDerWaalsContact O-N 3.07Å; I336-T340 PolarHBondContact O-OG1 2.87Å; I336-L488 HydrophobicContact CD1-CD1 3.86Å; I336-T491 HydrophobicContact CB-CG2 4.06Å; I336-T491 HydrophobicContact CG2-CG2 3.99Å; I336-A495 HydrophobicContact CG2-CB 3.73Å
337	L	95.4	Very high	92.2	Very high	0 Å²	0	33 Å²	33	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-61.4	-46.4	178.1	-177.4	62.6	0	0	0	112	L120 V139 P140 G333 G334 K339 T340 V341 T353 T491	L120-L337 HydrophobicContact CD2-CD2 4.26Å; V139-L337 HydrophobicContact CB-CD2 4.26Å; V139-L337 HydrophobicContact CG1-CD2 4.2Å; P140-L337 HydrophobicContact CG-CD2 3.92Å; G333-L337 PolarHBondContact O-N 3.02Å; G334-L337 WeakPolarHBondContact O-CB 3.25Å; G334-L337 PolarHBondContact O-N 2.96Å; L337-K339 PolarHBondContact O-N 3.26Å; L337-T340 WeakPolarHBondContact CA-OG1 3.35Å; L337-T340 PolarHBondContact O-N 2.97Å; L337-T340 PolarHBondContact O-OG1 3.49Å; L337-V341 HydrophobicContact CD1-CG2 3.56Å; L337-V341 HydrophobicContact CG-CG2 4.23Å; L337-V341 WeakPolarHBondContact O-CB 3.5Å; L337-V341 WeakPolarHBondContact O-CG2 3.47Å; L337-V341 PolarHBondContact O-N 2.87Å; L337-T353 HydrophobicContact CD1-CG2 3.99Å; L337-T353 WeakPolarHBondContact CD1-OG1 3.42Å; L337-T353 HydrophobicContact CD2-CG2 4.32Å; L337-T491 HydrophobicContact CB-CG2 4.01Å
338	D	94.6	Very high	91.9	Very high	0 Å²	0	32.9 Å²	32.9	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-54.6	-52.6	175.7	167.2	57.9	0	0	0	111.9	T133 F136 I137 G334 T340 S342	T133-D338 WeakPolarHBondContact CB-OD1 3.34Å; T133-D338 PolarHBondContact OG1-OD1 2.92Å; F136-D338 HydrophobicContact CB-CB 3.92Å; I137-D338 HydrophobicContact CD1-CB 4.37Å; I137-D338 HydrophobicContact CG1-CB 3.63Å; G334-D338 PolarHBondContact O-N 2.88Å; D338-T340 VanDerWaalsContact C-N 3.28Å; D338-T340 PolarHBondContact O-N 2.9Å; D338-S342 WeakPolarHBondContact O-CB 3.31Å; D338-S342 PolarHBondContact O-N 3.36Å; D338-S342 PolarHBondContact O-OG 2.95Å
339	K	92.9	Very high	91.8	Very high	85 Å²	85	30.9 Å²	30.9	37%	0.37	18%	0.177	S	C	.	.	H	α-helix	trans	-68.1	-26.4	-177	-66.6	-64.9	169.6	-165.1	0	113.9	D206 L335 I336 L337	D206-K339 IonicContact OD1-NZ 2.83Å; D206-K339 PolarHBondContact OD1-NZ 3.26Å; D206-K339 IonicContact OD2-NZ 2.77Å; D206-K339 PolarHBondContact OD2-NZ 3.28Å; L335-K339 WeakPolarHBondContact O-CG 3.28Å; L335-K339 PolarHBondContact O-N 3.43Å; I336-K339 PolarHBondContact O-N 3.19Å; L337-K339 PolarHBondContact O-N 3.26Å
340	T	92.6	Very high	91.6	Very high	17 Å²	17	28.6 Å²	28.6	10%	0.104	17%	0.165	C	C	.	.	H	α-helix	trans	-85.1	-49.6	179.2	48.7	0	0	0	0	111.5	I336 L337 D338 S342 D343 F346 M349 A495	I336-T340 HydrophobicContact CG2-CG2 4.35Å; I336-T340 WeakPolarHBondContact O-CB 3.29Å; I336-T340 VanDerWaalsContact O-CG2 3.29Å; I336-T340 WeakPolarHBondContact O-CG2 3.29Å; I336-T340 PolarHBondContact O-N 3.17Å; I336-T340 VanDerWaalsContact O-N 3.07Å; I336-T340 PolarHBondContact O-OG1 2.87Å; L337-T340 WeakPolarHBondContact CA-OG1 3.35Å; L337-T340 PolarHBondContact O-N 2.97Å; L337-T340 PolarHBondContact O-OG1 3.49Å; D338-T340 VanDerWaalsContact C-N 3.28Å; D338-T340 PolarHBondContact O-N 2.9Å; T340-S342 VanDerWaalsContact C-N 3.26Å; T340-S342 PolarHBondContact O-N 3.14Å; T340-D343 WeakPolarHBondContact O-CB 3.44Å; T340-D343 PolarHBondContact O-N 3.29Å; T340-F346 WeakPolarHBondContact O-CB 3.39Å; T340-M349 VanDerWaalsContact CB-CE 3.4Å; T340-M349 VanDerWaalsContact CB-SD 3.55Å; T340-M349 HydrophobicContact CG2-CE 3.53Å; T340-M349 HydrophobicContact CG2-SD 3.87Å; T340-M349 PolarHBondContact OG1-SD 3.25Å; T340-A495 HydrophobicContact CG2-CB 3.71Å
341	V	91	Very high	91.6	Very high	10 Å²	10	28.5 Å²	28.5	6%	0.061	17%	0.165	C	C	.	.	H	α-helix	trans	-66.3	-29.9	179.4	173.9	0	0	0	0	112.1	Q124 F136 L337 D343 A350	Q124-V341 HydrophobicContact CB-CG1 4.06Å; F136-V341 HydrophobicContact CD1-CG1 4.28Å; F136-V341 HydrophobicContact CE1-CB 4.38Å; F136-V341 HydrophobicContact CE1-CG1 3.64Å; F136-V341 HydrophobicContact CE2-CG1 4.06Å; F136-V341 HydrophobicContact CZ-CB 4.43Å; F136-V341 HydrophobicContact CZ-CG1 3.51Å; L337-V341 HydrophobicContact CD1-CG2 3.56Å; L337-V341 HydrophobicContact CG-CG2 4.23Å; L337-V341 WeakPolarHBondContact O-CB 3.5Å; L337-V341 WeakPolarHBondContact O-CG2 3.47Å; L337-V341 PolarHBondContact O-N 2.87Å; V341-D343 PolarHBondContact O-N 3.16Å; V341-A350 HydrophobicContact CG2-CB 4.14Å
342	S	88.5	Confident	91.5	Very high	60 Å²	60	28.5 Å²	28.5	42%	0.42	17%	0.165	S	C	.	.	T	Hydrogen-bonded Turn	trans	-68.9	-16.7	173.9	-61.9	0	0	0	0	113.8	D338 T340	D338-S342 WeakPolarHBondContact O-CB 3.31Å; D338-S342 PolarHBondContact O-N 3.36Å; D338-S342 PolarHBondContact O-OG 2.95Å; T340-S342 VanDerWaalsContact C-N 3.26Å; T340-S342 PolarHBondContact O-N 3.14Å
343	D	88.4	Confident	91.5	Very high	53 Å²	53	25.8 Å²	25.8	28%	0.283	15%	0.148	S	C	.	.	S	Bend	trans	-89.4	119.3	172.9	-173.2	-24.2	0	0	0	109.3	T340 V341 N345 F346 A347	T340-D343 WeakPolarHBondContact O-CB 3.44Å; T340-D343 PolarHBondContact O-N 3.29Å; V341-D343 PolarHBondContact O-N 3.16Å; D343-N345 PolarHBondContact O-N 3.43Å; D343-N345 WeakPolarHBondContact OD1-CB 3.09Å; D343-N345 PolarHBondContact OD1-N 2.93Å; D343-N345 PolarHBondContact OD1-ND2 3.49Å; D343-F346 HydrophobicContact CB-CD2 3.78Å; D343-F346 HydrophobicContact CB-CE2 4.42Å; D343-F346 PolarHBondContact O-N 3.11Å; D343-F346 WeakPolarHBondContact OD2-CE2 3.36Å; D343-A347 PolarHBondContact O-N 3.46Å
344	P	84.6	Confident	91.5	Very high	110 Å²	110	25.9 Å²	25.9	71%	0.714	15%	0.149	S	C	*	.	G	3₁₀ helix	trans	-53.8	-27.8	179	-26.7	34.8	0	0	0	114.1	F346	P344-F346 PolarHBondContact O-N 3.41Å
345	N	83.7	Confident	91.5	Very high	70 Å²	70	25.9 Å²	25.9	37%	0.374	15%	0.149	S	C	.	.	G	3₁₀ helix	trans	-69.7	-18.1	178.2	-60.2	-74.1	0	0	0	113.1	D343 W502	D343-N345 PolarHBondContact O-N 3.43Å; D343-N345 WeakPolarHBondContact OD1-CB 3.09Å; D343-N345 PolarHBondContact OD1-N 2.93Å; D343-N345 PolarHBondContact OD1-ND2 3.49Å; N345-W502 PolarHBondContact OD1-NE1 3.15Å
346	F	87.4	Confident	91.5	Very high	19 Å²	19	24 Å²	24	8%	0.083	14%	0.139	C	C	.	.	G	3₁₀ helix	trans	-125	14.6	-175.6	-49.2	-55.3	0	0	0	113	T340 D343 P344 G348 M349 F498 H499 W502	T340-F346 WeakPolarHBondContact O-CB 3.39Å; D343-F346 HydrophobicContact CB-CD2 3.78Å; D343-F346 HydrophobicContact CB-CE2 4.42Å; D343-F346 PolarHBondContact O-N 3.11Å; D343-F346 WeakPolarHBondContact OD2-CE2 3.36Å; P344-F346 PolarHBondContact O-N 3.41Å; F346-G348 PolarHBondContact O-N 3.07Å; F346-G348 VanDerWaalsContact O-N 3.1Å; F346-M349 HydrophobicContact CB-CE 4.19Å; F346-M349 WeakPolarHBondContact O-CB 3.2Å; F346-M349 PolarHBondContact O-N 2.97Å; F346-F498 HydrophobicContact CD1-CB 3.71Å; F346-F498 HydrophobicContact CD1-CD1 4.14Å; F346-F498 HydrophobicContact CD1-CG 4.38Å; F346-F498 HydrophobicContact CE1-CB 4.18Å; F346-F498 WeakPolarHBondContact CE1-O 3.46Å; F346-F498 HydrophobicContact CG-CB 4.49Å; F346-H499 AromaticContact CZ-ND1 3.94Å; F346-W502 HydrophobicContact CE1-CB 3.78Å; F346-W502 HydrophobicContact CE1-CG 4.18Å; F346-W502 HydrophobicContact CZ-CB 4.22Å; F346-W502 HydrophobicContact CZ-CG 4.28Å
347	A	84.5	Confident	91.4	Very high	20 Å²	20	22 Å²	22	17%	0.165	13%	0.129	C	C	.	.	T	Hydrogen-bonded Turn	trans	-55	-30.7	179.2	0	0	0	0	0	113.3	Q124 D343 M349 A350	Q124-A347 PolarHBondContact NE2-O 2.89Å; Q124-A347 VanDerWaalsContact NE2-O 3.1Å; Q124-A347 PolarHBondContact OE1-O 3.24Å; D343-A347 PolarHBondContact O-N 3.46Å; A347-M349 PolarHBondContact O-N 2.98Å; A347-M349 VanDerWaalsContact O-N 3.14Å; A347-A350 PolarHBondContact O-N 3.07Å
348	G	87.3	Confident	91.3	Very high	5 Å²	5	22.5 Å²	22.5	5%	0.052	13%	0.134	C	C	.	.	T	Hydrogen-bonded Turn	trans	-64	-15.2	175.6	0	0	0	0	0	114.9	F346 A350 V351 F352 G433	F346-G348 PolarHBondContact O-N 3.07Å; F346-G348 VanDerWaalsContact O-N 3.1Å; G348-A350 PolarHBondContact O-N 3.49Å; G348-V351 WeakPolarHBondContact O-CG1 3.35Å; G348-V351 PolarHBondContact O-N 3.4Å; G348-F352 WeakPolarHBondContact O-CD2 3.36Å; G348-F352 WeakPolarHBondContact O-CE2 3.48Å; G348-G433 WeakPolarHBondContact CA-O 3.3Å
349	M	91.8	Very high	91.2	Very high	0 Å²	0	22.6 Å²	22.6	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-62.6	-26	177.8	-166.8	178.7	-51.2	0	0	113.3	T340 F346 A347 V351 F352 T353 L494 A495 F498	T340-M349 VanDerWaalsContact CB-CE 3.4Å; T340-M349 VanDerWaalsContact CB-SD 3.55Å; T340-M349 HydrophobicContact CG2-CE 3.53Å; T340-M349 HydrophobicContact CG2-SD 3.87Å; T340-M349 PolarHBondContact OG1-SD 3.25Å; F346-M349 HydrophobicContact CB-CE 4.19Å; F346-M349 WeakPolarHBondContact O-CB 3.2Å; F346-M349 PolarHBondContact O-N 2.97Å; A347-M349 PolarHBondContact O-N 2.98Å; A347-M349 VanDerWaalsContact O-N 3.14Å; M349-V351 VanDerWaalsContact C-N 3.35Å; M349-V351 PolarHBondContact O-N 2.97Å; M349-F352 PolarHBondContact O-N 3.47Å; M349-T353 PolarHBondContact O-N 3.48Å; M349-T353 PolarHBondContact O-OG1 3.49Å; M349-L494 HydrophobicContact CG-CD2 3.61Å; M349-L494 HydrophobicContact CG-CG 3.93Å; M349-L494 HydrophobicContact SD-CD2 4.48Å; M349-L494 HydrophobicContact SD-CG 4.44Å; M349-A495 VanDerWaalsContact CE-CA 3.42Å; M349-A495 HydrophobicContact CE-CB 3.86Å; M349-A495 HydrophobicContact SD-CB 4.03Å; M349-F498 HydrophobicContact CB-CD2 4.44Å; M349-F498 HydrophobicContact CB-CE2 4.22Å; M349-F498 HydrophobicContact CB-CZ 4.4Å; M349-F498 HydrophobicContact CE-CB 3.89Å; M349-F498 HydrophobicContact CE-CD2 3.97Å; M349-F498 HydrophobicContact CE-CG 3.99Å; M349-F498 HydrophobicContact CG-CD2 4.39Å; M349-F498 HydrophobicContact CG-CE2 4.34Å
350	A	93	Very high	91.2	Very high	0 Å²	0	18.6 Å²	18.6	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-54.8	-46.2	180	0	0	0	0	0	112.4	L120 Q124 V341 A347 G348 F352 P354	L120-A350 WeakPolarHBondContact CD2-O 3.43Å; L120-A350 HydrophobicContact CG-CB 4.08Å; Q124-A350 HydrophobicContact CG-CB 4.34Å; Q124-A350 VanDerWaalsContact NE2-CB 3.34Å; V341-A350 HydrophobicContact CG2-CB 4.14Å; A347-A350 PolarHBondContact O-N 3.07Å; G348-A350 PolarHBondContact O-N 3.49Å; A350-F352 VanDerWaalsContact C-N 3.33Å; A350-F352 PolarHBondContact O-N 3.46Å; A350-P354 WeakPolarHBondContact O-CD 3.28Å
351	V	94	Very high	91.1	Very high	0 Å²	0	18 Å²	18	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-69.7	-32.1	-177.9	76.8	0	0	0	0	112.7	G117 M118 D121 G348 M349 I427	G117-V351 WeakPolarHBondContact CA-O 3.32Å; G117-V351 WeakPolarHBondContact O-CA 3.27Å; M118-V351 HydrophobicContact SD-CG2 3.69Å; D121-V351 HydrophobicContact CB-CB 4.05Å; D121-V351 HydrophobicContact CB-CG2 4.36Å; G348-V351 WeakPolarHBondContact O-CG1 3.35Å; G348-V351 PolarHBondContact O-N 3.4Å; M349-V351 VanDerWaalsContact C-N 3.35Å; M349-V351 PolarHBondContact O-N 2.97Å; V351-I427 HydrophobicContact CG1-CG2 4.01Å; V351-I427 HydrophobicContact CG2-CD1 4.23Å; V351-I427 HydrophobicContact CG2-CG1 4.21Å; V351-I427 HydrophobicContact CG2-CG2 3.89Å
352	F	94.7	Very high	90.9	Very high	0 Å²	0	18.6 Å²	18.6	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-88.1	-23.4	-172.7	-62.6	-64.6	0	0	0	113.5	G348 M349 A350 V355 I356 L424 I427 T435 L437 F441 Y445 L494 F498	G348-F352 WeakPolarHBondContact O-CD2 3.36Å; G348-F352 WeakPolarHBondContact O-CE2 3.48Å; M349-F352 PolarHBondContact O-N 3.47Å; A350-F352 VanDerWaalsContact C-N 3.33Å; A350-F352 PolarHBondContact O-N 3.46Å; F352-V355 PolarHBondContact O-N 2.98Å; F352-I356 PolarHBondContact O-N 2.88Å; F352-L424 HydrophobicContact CD1-CD2 3.76Å; F352-L424 HydrophobicContact CE1-CD2 3.47Å; F352-L424 VanDerWaalsContact CE1-CD2 3.47Å; F352-I427 HydrophobicContact CD1-CD1 3.8Å; F352-I427 HydrophobicContact CE1-CD1 3.79Å; F352-I427 HydrophobicContact CE1-CG2 4.13Å; F352-I427 HydrophobicContact CZ-CG2 4.36Å; F352-T435 WeakPolarHBondContact CE2-OG1 3.41Å; F352-L437 HydrophobicContact CE1-CD2 4.27Å; F352-L437 HydrophobicContact CZ-CD2 4.03Å; F352-F441 HydrophobicContact CD1-CZ 4.3Å; F352-F441 AromaticContact CD2-CZ 3.82Å; F352-F441 HydrophobicContact CD2-CZ 3.82Å; F352-F441 AromaticContact CE1-CE1 4Å; F352-F441 HydrophobicContact CE1-CE1 4Å; F352-F441 HydrophobicContact CE1-CZ 4.03Å; F352-F441 HydrophobicContact CE2-CE1 4.12Å; F352-F441 HydrophobicContact CE2-CE2 4.29Å; F352-F441 AromaticContact CE2-CZ 3.51Å; F352-F441 HydrophobicContact CE2-CZ 3.51Å; F352-F441 HydrophobicContact CG-CZ 4.22Å; F352-F441 AromaticContact CZ-CE1 3.75Å; F352-F441 HydrophobicContact CZ-CE1 3.75Å; F352-F441 AromaticContact CZ-CZ 3.63Å; F352-F441 HydrophobicContact CZ-CZ 3.63Å; F352-Y445 HydrophobicContact CB-CE2 4.01Å; F352-Y445 HydrophobicContact CD1-CE2 4.09Å; F352-Y445 HydrophobicContact CG-CE2 4.28Å; F352-L494 HydrophobicContact CB-CD1 4.29Å; F352-L494 HydrophobicContact CB-CD2 3.74Å; F352-F498 HydrophobicContact CD2-CE2 4.11Å; F352-F498 AromaticContact CD2-CZ 3.82Å; F352-F498 HydrophobicContact CD2-CZ 3.82Å; F352-F498 HydrophobicContact CE2-CZ 4.09Å
353	T	95.2	Very high	91.1	Very high	3 Å²	3	15.9 Å²	15.9	2%	0.018	10%	0.098	C	C	.	.	H	α-helix	trans	-63.5	-50.4	-174.9	-61.3	0	0	0	0	112.7	L337 M349 V355 I356 N357 T491	L337-T353 HydrophobicContact CD1-CG2 3.99Å; L337-T353 WeakPolarHBondContact CD1-OG1 3.42Å; L337-T353 HydrophobicContact CD2-CG2 4.32Å; M349-T353 PolarHBondContact O-N 3.48Å; M349-T353 PolarHBondContact O-OG1 3.49Å; T353-V355 PolarHBondContact O-N 3.39Å; T353-I356 WeakPolarHBondContact O-CG2 3.38Å; T353-I356 PolarHBondContact O-N 3.03Å; T353-N357 WeakPolarHBondContact CG2-ND2 3.44Å; T353-N357 VanDerWaalsContact O-CB 3.32Å; T353-N357 WeakPolarHBondContact O-CB 3.35Å; T353-N357 VanDerWaalsContact O-CG 3.28Å; T353-N357 PolarHBondContact O-N 3.35Å; T353-T491 HydrophobicContact CG2-CG2 4.19Å
354	P	94.9	Very high	91.2	Very high	2 Å²	2	13.4 Å²	13.4	1%	0.013	9%	0.085	C	C	.	.	H	α-helix	trans	-60.7	-32.3	176.5	-27.6	39.6	0	0	0	112.8	T113 A116 L120 A350 G358	T113-P354 WeakPolarHBondContact CB-O 3.39Å; A116-P354 HydrophobicContact CB-CB 4.08Å; L120-P354 HydrophobicContact CB-CG 4.48Å; L120-P354 HydrophobicContact CD2-CG 3.92Å; A350-P354 WeakPolarHBondContact O-CD 3.28Å; P354-G358 WeakPolarHBondContact O-CA 3.36Å; P354-G358 PolarHBondContact O-N 2.56Å
355	V	95.3	Very high	91.3	Very high	0 Å²	0	8.5 Å²	8.5	0%	0	5%	0.053	C	C	.	.	H	α-helix	trans	-69.7	-51.2	179.2	-177.1	0	0	0	0	111.6	V114 F352 T353 V359 F423 I427	V114-V355 HydrophobicContact CB-CG2 4.33Å; V114-V355 HydrophobicContact CG2-CG1 4.43Å; V114-V355 HydrophobicContact CG2-CG2 3.76Å; F352-V355 PolarHBondContact O-N 2.98Å; T353-V355 PolarHBondContact O-N 3.39Å; V355-V359 HydrophobicContact CG1-CG2 4.22Å; V355-V359 WeakPolarHBondContact O-CB 3.45Å; V355-V359 WeakPolarHBondContact O-CG2 3.34Å; V355-V359 PolarHBondContact O-N 3.07Å; V355-F423 HydrophobicContact CG1-CB 3.97Å; V355-F423 HydrophobicContact CG1-CD2 4.11Å; V355-F423 HydrophobicContact CG1-CG 4.36Å; V355-I427 HydrophobicContact CG2-CD1 4.18Å
356	I	95.4	Very high	91.3	Very high	0 Å²	0	7.3 Å²	7.3	0%	0	5%	0.049	C	C	.	.	H	α-helix	trans	-66	-41.7	-178.7	-164.6	162.6	0	0	0	111.5	F352 T353 G360 Y445 A448 A449 Q452 L494	F352-I356 PolarHBondContact O-N 2.88Å; T353-I356 WeakPolarHBondContact O-CG2 3.38Å; T353-I356 PolarHBondContact O-N 3.03Å; I356-G360 PolarHBondContact O-N 2.94Å; I356-Y445 HydrophobicContact CD1-CE2 4.47Å; I356-A448 HydrophobicContact CD1-CB 4.1Å; I356-A449 HydrophobicContact CD1-CB 4.26Å; I356-A449 HydrophobicContact CG1-CB 4.42Å; I356-Q452 PolarHBondContact O-NE2 3.1Å; I356-Q452 PolarHBondContact O-OE1 2.98Å; I356-Q452 VanDerWaalsContact O-OE1 3.07Å; I356-L494 HydrophobicContact CD1-CB 4.32Å; I356-L494 HydrophobicContact CG2-CB 4.43Å; I356-L494 HydrophobicContact CG2-CD2 3.98Å
357	N	94.8	Very high	91.4	Very high	8 Å²	8	6.5 Å²	6.5	4%	0.043	5%	0.045	C	C	.	.	H	α-helix	trans	-69.4	-51.1	179.2	-67.4	-5.5	0	0	0	111.2	T353 G360 G361 D487 G490 T491	T353-N357 WeakPolarHBondContact CG2-ND2 3.44Å; T353-N357 VanDerWaalsContact O-CB 3.32Å; T353-N357 WeakPolarHBondContact O-CB 3.35Å; T353-N357 VanDerWaalsContact O-CG 3.28Å; T353-N357 PolarHBondContact O-N 3.35Å; N357-G360 PolarHBondContact O-N 2.95Å; N357-G361 PolarHBondContact O-N 3.46Å; N357-D487 PolarHBondContact OD1-O 3.3Å; N357-G490 VanDerWaalsContact OD1-CA 3.28Å; N357-G490 WeakPolarHBondContact OD1-CA 3.27Å; N357-T491 PolarHBondContact ND2-OG1 3.44Å; N357-T491 PolarHBondContact OD1-N 3.25Å; N357-T491 VanDerWaalsContact OD1-N 3.11Å; N357-T491 PolarHBondContact OD1-OG1 3.42Å
358	G	92.2	Very high	91.5	Very high	10 Å²	10	5.6 Å²	5.6	10%	0.103	4%	0.037	C	C	.	.	H	α-helix	trans	-64	-45.2	-177.4	0	0	0	0	0	112.5	P354 G361 N362	P354-G358 WeakPolarHBondContact O-CA 3.36Å; P354-G358 PolarHBondContact O-N 2.56Å; G358-G361 PolarHBondContact O-N 2.69Å; G358-N362 VanDerWaalsContact O-CB 3.29Å; G358-N362 WeakPolarHBondContact O-CB 3.43Å; G358-N362 PolarHBondContact O-N 2.98Å; G358-N362 PolarHBondContact O-ND2 3.4Å
359	V	93	Very high	91.2	Very high	3 Å²	3	7.4 Å²	7.4	2%	0.018	5%	0.049	C	C	.	.	H	α-helix	trans	-63	-47.6	178.2	175.1	0	0	0	0	111.3	F106 V355 N362 L363 H420 F423	F106-V359 HydrophobicContact CE2-CG1 3.51Å; F106-V359 HydrophobicContact CZ-CG1 3.87Å; V355-V359 HydrophobicContact CG1-CG2 4.22Å; V355-V359 WeakPolarHBondContact O-CB 3.45Å; V355-V359 WeakPolarHBondContact O-CG2 3.34Å; V355-V359 PolarHBondContact O-N 3.07Å; V359-N362 PolarHBondContact O-N 2.92Å; V359-L363 HydrophobicContact CG1-CD1 4.17Å; V359-L363 WeakPolarHBondContact O-CG 3.24Å; V359-L363 PolarHBondContact O-N 2.72Å; V359-L363 VanDerWaalsContact O-N 3.08Å; V359-H420 WeakPolarHBondContact CG1-NE2 3.49Å; V359-F423 HydrophobicContact CG2-CD2 3.86Å; V359-F423 HydrophobicContact CG2-CE2 3.59Å
360	G	93.2	Very high	90.8	Very high	0 Å²	0	9.6 Å²	9.6	0%	0	6%	0.057	C	C	.	.	H	α-helix	trans	-62.4	-45.5	177.7	0	0	0	0	0	112.9	I356 N357 N362 L363 V364	I356-G360 PolarHBondContact O-N 2.94Å; N357-G360 PolarHBondContact O-N 2.95Å; G360-N362 PolarHBondContact O-N 2.83Å; G360-L363 PolarHBondContact O-N 2.91Å; G360-V364 WeakPolarHBondContact O-CG1 3.45Å; G360-V364 PolarHBondContact O-N 3.29Å
361	G	90.8	Very high	90.4	Very high	5 Å²	5	9.6 Å²	9.6	5%	0.052	6%	0.057	C	C	.	.	H	α-helix	trans	-60.2	-42	176.9	0	0	0	0	0	113.1	N357 G358 V364 A365	N357-G361 PolarHBondContact O-N 3.46Å; G358-G361 PolarHBondContact O-N 2.69Å; G361-V364 VanDerWaalsContact O-CG1 3.32Å; G361-V364 WeakPolarHBondContact O-CG1 3.22Å; G361-A365 VanDerWaalsContact O-CB 3.28Å; G361-A365 WeakPolarHBondContact O-CB 3.43Å; G361-A365 PolarHBondContact O-N 3.1Å
362	N	87.2	Confident	89.8	Confident	22 Å²	22	9.6 Å²	9.6	12%	0.118	6%	0.057	C	C	.	.	H	α-helix	trans	-68.7	-44.8	178.7	-67.8	-32.1	0	0	0	112.1	A259 G358 V359 G360 V364 A365 V366	A259-N362 WeakPolarHBondContact CB-OD1 3.36Å; G358-N362 VanDerWaalsContact O-CB 3.29Å; G358-N362 WeakPolarHBondContact O-CB 3.43Å; G358-N362 PolarHBondContact O-N 2.98Å; G358-N362 PolarHBondContact O-ND2 3.4Å; V359-N362 PolarHBondContact O-N 2.92Å; G360-N362 PolarHBondContact O-N 2.83Å; N362-V364 PolarHBondContact O-N 3.3Å; N362-A365 PolarHBondContact O-N 3.13Å; N362-V366 WeakPolarHBondContact O-CG2 3.48Å; N362-V366 PolarHBondContact O-N 3.15Å; N362-V366 VanDerWaalsContact O-N 3.07Å
363	L	90.9	Very high	89	Confident	3 Å²	3	12.4 Å²	12.4	2%	0.016	8%	0.075	C	C	.	.	H	α-helix	trans	-61.9	-44.5	178.3	-72.6	175.5	0	0	0	111.7	F106 V359 G360 V366 Q367 L412 L415 V416 V453	F106-L363 HydrophobicContact CD2-CD2 3.58Å; F106-L363 HydrophobicContact CD2-CG 4.09Å; F106-L363 HydrophobicContact CE2-CD1 3.94Å; F106-L363 HydrophobicContact CE2-CD2 3.71Å; F106-L363 HydrophobicContact CE2-CG 3.88Å; V359-L363 HydrophobicContact CG1-CD1 4.17Å; V359-L363 WeakPolarHBondContact O-CG 3.24Å; V359-L363 PolarHBondContact O-N 2.72Å; V359-L363 VanDerWaalsContact O-N 3.08Å; G360-L363 PolarHBondContact O-N 2.91Å; L363-V366 PolarHBondContact O-N 3.29Å; L363-Q367 PolarHBondContact O-N 3.09Å; L363-L412 HydrophobicContact CD2-CB 4.18Å; L363-L412 HydrophobicContact CD2-CD2 3.68Å; L363-L412 HydrophobicContact CD2-CG 4.48Å; L363-L415 HydrophobicContact CD2-CD2 4.42Å; L363-V416 HydrophobicContact CD1-CG2 3.73Å; L363-V453 HydrophobicContact CD1-CG1 4.09Å; L363-V453 HydrophobicContact CD1-CG2 4.12Å
364	V	91.6	Very high	88.3	Confident	1 Å²	1	15.3 Å²	15.3	1%	0.006	9%	0.087	C	C	.	.	H	α-helix	trans	-70.8	-34	-179.3	75.9	0	0	0	0	112.1	G360 G361 N362 Q367 A368 L456 A460 L482	G360-V364 WeakPolarHBondContact O-CG1 3.45Å; G360-V364 PolarHBondContact O-N 3.29Å; G361-V364 VanDerWaalsContact O-CG1 3.32Å; G361-V364 WeakPolarHBondContact O-CG1 3.22Å; N362-V364 PolarHBondContact O-N 3.3Å; V364-Q367 PolarHBondContact O-N 3.08Å; V364-A368 WeakPolarHBondContact O-CB 3.42Å; V364-A368 PolarHBondContact O-N 2.91Å; V364-L456 HydrophobicContact CB-CB 4Å; V364-L456 HydrophobicContact CB-CD1 4.4Å; V364-L456 HydrophobicContact CG1-CD1 4.28Å; V364-L456 HydrophobicContact CG2-CB 3.83Å; V364-L456 WeakPolarHBondContact CG2-O 3.41Å; V364-A460 HydrophobicContact CG2-CB 3.67Å; V364-L482 HydrophobicContact CG1-CB 3.79Å; V364-L482 HydrophobicContact CG2-CB 3.88Å; V364-L482 HydrophobicContact CG2-CD1 4.02Å; V364-L482 HydrophobicContact CG2-CD2 3.9Å; V364-L482 HydrophobicContact CG2-CG 4.11Å
365	A	86.4	Confident	87.7	Confident	7 Å²	7	16.1 Å²	16.1	6%	0.058	9%	0.091	C	C	.	.	H	α-helix	trans	-63.3	-43.8	173.6	0	0	0	0	0	111.7	M151 G361 N362 Q367 A368 S369 I479	M151-A365 HydrophobicContact CE-CB 4.44Å; M151-A365 HydrophobicContact SD-CB 4.14Å; G361-A365 VanDerWaalsContact O-CB 3.28Å; G361-A365 WeakPolarHBondContact O-CB 3.43Å; G361-A365 PolarHBondContact O-N 3.1Å; N362-A365 PolarHBondContact O-N 3.13Å; A365-Q367 VanDerWaalsContact C-N 3.35Å; A365-Q367 PolarHBondContact O-N 2.6Å; A365-A368 PolarHBondContact O-N 2.96Å; A365-S369 WeakPolarHBondContact O-CB 3.33Å; A365-S369 PolarHBondContact O-N 3.28Å; A365-I479 HydrophobicContact CB-CG2 4.11Å
366	V	83	Confident	86.8	Confident	46 Å²	46	19.7 Å²	19.7	28%	0.279	11%	0.108	S	C	.	.	H	α-helix	trans	-59.9	-45.3	173.4	170.7	0	0	0	0	110.7	V102 N362 L363 R370 L412	V102-V366 HydrophobicContact CG2-CG1 4.34Å; N362-V366 WeakPolarHBondContact O-CG2 3.48Å; N362-V366 PolarHBondContact O-N 3.15Å; N362-V366 VanDerWaalsContact O-N 3.07Å; L363-V366 PolarHBondContact O-N 3.29Å; V366-R370 VanDerWaalsContact O-CG 3.27Å; V366-R370 WeakPolarHBondContact O-CG 3.21Å; V366-R370 PolarHBondContact O-N 3.34Å; V366-L412 HydrophobicContact CG1-CD1 4.47Å; V366-L412 HydrophobicContact CG1-CD2 4.26Å
367	Q	89.3	Confident	85.8	Confident	2 Å²	2	26.4 Å²	26.4	1%	0.009	14%	0.141	C	C	.	.	H	α-helix	trans	-63.2	-46.9	177.9	-175.4	64.1	6.5	0	0	112.1	L363 V364 A365 S369 R370 I371 N405 S408 L412 L457 A460	L363-Q367 PolarHBondContact O-N 3.09Å; V364-Q367 PolarHBondContact O-N 3.08Å; A365-Q367 VanDerWaalsContact C-N 3.35Å; A365-Q367 PolarHBondContact O-N 2.6Å; Q367-S369 PolarHBondContact O-N 3.18Å; Q367-R370 PolarHBondContact O-N 3.35Å; Q367-I371 HydrophobicContact CG-CD1 3.9Å; Q367-I371 HydrophobicContact CG-CG1 4.43Å; Q367-I371 VanDerWaalsContact O-CG1 3.31Å; Q367-I371 WeakPolarHBondContact O-CG1 2.74Å; Q367-I371 PolarHBondContact O-N 3.47Å; Q367-N405 PolarHBondContact NE2-O 3.03Å; Q367-S408 PolarHBondContact OE1-OG 3.32Å; Q367-L412 HydrophobicContact CB-CD1 3.68Å; Q367-L412 HydrophobicContact CG-CD1 4.39Å; Q367-L457 HydrophobicContact CB-CD2 3.68Å; Q367-L457 HydrophobicContact CG-CD2 3.77Å; Q367-A460 HydrophobicContact CG-CB 4.5Å
368	A	87.6	Confident	85	Confident	0 Å²	0	30.3 Å²	30.3	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-61.4	-44.1	-178.9	0	0	0	0	0	111.8	V364 A365 R370 I371 S372 V464 I479 L482	V364-A368 WeakPolarHBondContact O-CB 3.42Å; V364-A368 PolarHBondContact O-N 2.91Å; A365-A368 PolarHBondContact O-N 2.96Å; A368-R370 PolarHBondContact O-N 2.81Å; A368-I371 PolarHBondContact O-N 3.48Å; A368-S372 VanDerWaalsContact O-CB 3.28Å; A368-S372 WeakPolarHBondContact O-CB 3.12Å; A368-S372 PolarHBondContact O-N 3.04Å; A368-V464 HydrophobicContact CB-CG2 4.16Å; A368-I479 HydrophobicContact CB-CG1 4.36Å; A368-L482 HydrophobicContact CB-CD1 3.62Å
369	S	81.4	Confident	84.2	Confident	43 Å²	43	31 Å²	31	30%	0.301	17%	0.17	S	C	.	.	H	α-helix	trans	-62.2	-40.8	176.1	175.3	0	0	0	0	112.2	A365 Q367 S372 T373	A365-S369 WeakPolarHBondContact O-CB 3.33Å; A365-S369 PolarHBondContact O-N 3.28Å; Q367-S369 PolarHBondContact O-N 3.18Å; S369-S372 PolarHBondContact O-N 2.72Å; S369-T373 WeakPolarHBondContact O-CB 3.33Å; S369-T373 PolarHBondContact O-N 2.83Å; S369-T373 PolarHBondContact O-OG1 2.85Å
370	R	81.9	Confident	83.4	Confident	46 Å²	46	36.9 Å²	36.9	17%	0.174	20%	0.198	C	C	.	.	H	α-helix	trans	-65.6	-44.5	176.8	-72.9	177.5	121.1	-114.5	-15	112.6	E93 V366 Q367 A368 T373 F374 S408	E93-R370 IonicContact OE1-NH2 3.25Å; E93-R370 IonicContact OE2-CZ 3.94Å; E93-R370 IonicContact OE2-NH1 3.79Å; E93-R370 IonicContact OE2-NH2 3.86Å; E93-R370 PolarHBondContact OE2-NH2 3.35Å; V366-R370 VanDerWaalsContact O-CG 3.27Å; V366-R370 WeakPolarHBondContact O-CG 3.21Å; V366-R370 PolarHBondContact O-N 3.34Å; Q367-R370 PolarHBondContact O-N 3.35Å; A368-R370 PolarHBondContact O-N 2.81Å; R370-T373 PolarHBondContact O-N 2.86Å; R370-F374 WeakPolarHBondContact O-CB 3.15Å; R370-F374 PolarHBondContact O-N 2.91Å; R370-S408 WeakPolarHBondContact CD-OG 3.09Å; R370-S408 PolarHBondContact NH1-OG 3.48Å
371	I	84.9	Confident	82.6	Confident	0 Å²	0	38.8 Å²	38.8	0%	0	21%	0.21	C	C	.	.	H	α-helix	trans	-63.6	-45.9	176.6	-61.2	169.8	0	0	0	109.8	Q367 A368 T373 F374 L375 N405 D461 V464	Q367-I371 HydrophobicContact CG-CD1 3.9Å; Q367-I371 HydrophobicContact CG-CG1 4.43Å; Q367-I371 VanDerWaalsContact O-CG1 3.31Å; Q367-I371 WeakPolarHBondContact O-CG1 2.74Å; Q367-I371 PolarHBondContact O-N 3.47Å; A368-I371 PolarHBondContact O-N 3.48Å; I371-T373 PolarHBondContact O-N 2.92Å; I371-F374 WeakPolarHBondContact O-CB 3.5Å; I371-F374 PolarHBondContact O-N 3.39Å; I371-L375 HydrophobicContact CG2-CD1 4.1Å; I371-L375 HydrophobicContact CG2-CG 4.48Å; I371-L375 WeakPolarHBondContact O-CG 3.28Å; I371-L375 PolarHBondContact O-N 2.84Å; I371-N405 HydrophobicContact CG1-CB 4.11Å; I371-D461 HydrophobicContact CD1-CB 4.32Å; I371-V464 HydrophobicContact CB-CB 4.49Å; I371-V464 HydrophobicContact CB-CG1 4Å; I371-V464 HydrophobicContact CG2-CB 4Å; I371-V464 HydrophobicContact CG2-CG1 3.45Å; I371-V464 VanDerWaalsContact CG2-CG1 3.45Å
372	S	82.6	Confident	81.7	Confident	0 Å²	0	39.9 Å²	39.9	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-57.4	-49.3	177.1	177.4	0	0	0	0	112	A368 S369 F374 L375 H376 P474 D475	A368-S372 VanDerWaalsContact O-CB 3.28Å; A368-S372 WeakPolarHBondContact O-CB 3.12Å; A368-S372 PolarHBondContact O-N 3.04Å; S369-S372 PolarHBondContact O-N 2.72Å; S372-F374 VanDerWaalsContact C-N 3.31Å; S372-F374 PolarHBondContact O-N 3.33Å; S372-L375 PolarHBondContact O-N 2.82Å; S372-H376 PolarHBondContact O-CD2 2.78Å; S372-H376 PolarHBondContact O-N 2.83Å; S372-P474 WeakPolarHBondContact OG-CG 3.46Å; S372-D475 WeakPolarHBondContact CB-OD1 3.45Å; S372-D475 PolarHBondContact OG-OD1 3.33Å; S372-D475 PolarHBondContact OG-OD2 3.33Å
373	T	77	Confident	80.7	Confident	59 Å²	59	44.9 Å²	44.9	36%	0.362	25%	0.245	S	C	.	.	H	α-helix	trans	-58.4	-44.2	176.9	-58.4	0	0	0	0	111.2	S369 R370 I371 L375 H376 M377	S369-T373 WeakPolarHBondContact O-CB 3.33Å; S369-T373 PolarHBondContact O-N 2.83Å; S369-T373 PolarHBondContact O-OG1 2.85Å; R370-T373 PolarHBondContact O-N 2.86Å; I371-T373 PolarHBondContact O-N 2.92Å; T373-L375 VanDerWaalsContact C-N 3.31Å; T373-L375 PolarHBondContact O-N 3.13Å; T373-H376 PolarHBondContact O-N 2.63Å; T373-M377 HydrophobicContact CG2-CE 3.81Å; T373-M377 HydrophobicContact CG2-SD 4.34Å; T373-M377 VanDerWaalsContact O-CG 3.32Å; T373-M377 WeakPolarHBondContact O-CG 3.2Å; T373-M377 PolarHBondContact O-N 3.42Å
374	F	80.3	Confident	78.9	Confident	65 Å²	65	49.2 Å²	49.2	29%	0.285	27%	0.268	S	S	.	.	H	α-helix	trans	-61.1	-39	176.6	176.5	-95.3	0	0	0	112.2	P90 R370 I371 S372 N378	P90-F374 HydrophobicContact CG-CE2 4.24Å; R370-F374 WeakPolarHBondContact O-CB 3.15Å; R370-F374 PolarHBondContact O-N 2.91Å; I371-F374 WeakPolarHBondContact O-CB 3.5Å; I371-F374 PolarHBondContact O-N 3.39Å; S372-F374 VanDerWaalsContact C-N 3.31Å; S372-F374 PolarHBondContact O-N 3.33Å; F374-N378 VanDerWaalsContact CE1-ND2 3.35Å; F374-N378 WeakPolarHBondContact CE1-ND2 3.16Å; F374-N378 WeakPolarHBondContact CE2-ND2 3.31Å; F374-N378 WeakPolarHBondContact CZ-ND2 3.12Å; F374-N378 PolarHBondContact O-N 3.2Å; F374-N378 PolarHBondContact O-ND2 2.95Å
375	L	82.3	Confident	76.9	Confident	18 Å²	18	51.3 Å²	51.3	9%	0.094	28%	0.282	C	S	.	.	H	α-helix	trans	-69.3	-45.1	177.5	-68.3	171.1	0	0	0	111.8	I371 S372 T373 M377 N378 G379 V464 W468	I371-L375 HydrophobicContact CG2-CD1 4.1Å; I371-L375 HydrophobicContact CG2-CG 4.48Å; I371-L375 WeakPolarHBondContact O-CG 3.28Å; I371-L375 PolarHBondContact O-N 2.84Å; S372-L375 PolarHBondContact O-N 2.82Å; T373-L375 VanDerWaalsContact C-N 3.31Å; T373-L375 PolarHBondContact O-N 3.13Å; L375-M377 VanDerWaalsContact C-N 3.27Å; L375-M377 PolarHBondContact O-N 3.07Å; L375-N378 PolarHBondContact O-N 3.45Å; L375-G379 PolarHBondContact O-N 3.18Å; L375-G379 VanDerWaalsContact O-N 3.07Å; L375-V464 HydrophobicContact CD1-CG1 3.72Å; L375-W468 HydrophobicContact CB-CD2 3.66Å; L375-W468 HydrophobicContact CB-CE3 3.59Å; L375-W468 HydrophobicContact CB-CG 4.37Å; L375-W468 HydrophobicContact CB-CH2 3.86Å; L375-W468 HydrophobicContact CB-CZ2 3.9Å; L375-W468 HydrophobicContact CB-CZ3 3.68Å; L375-W468 HydrophobicContact CD1-CB 3.86Å; L375-W468 HydrophobicContact CD1-CD2 3.88Å; L375-W468 HydrophobicContact CD1-CE3 4.02Å; L375-W468 HydrophobicContact CD1-CG 3.8Å; L375-W468 HydrophobicContact CD2-CD2 4.48Å; L375-W468 HydrophobicContact CD2-CG 4.41Å; L375-W468 HydrophobicContact CG-CD2 4.22Å; L375-W468 HydrophobicContact CG-CE3 4.41Å; L375-W468 HydrophobicContact CG-CG 4.43Å; L375-W468 WeakPolarHBondContact O-CH2 3.45Å; L375-W468 WeakPolarHBondContact O-CZ2 3.21Å
376	H	76.8	Confident	75	Confident	75 Å²	75	60.2 Å²	60.2	35%	0.347	32%	0.323	S	S	.	.	H	α-helix	trans	-61	-31.8	175	-82.3	-66.3	0	0	0	113.5	S372 T373 N378 W468 D473 D475	S372-H376 PolarHBondContact O-CD2 2.78Å; S372-H376 PolarHBondContact O-N 2.83Å; T373-H376 PolarHBondContact O-N 2.63Å; H376-N378 VanDerWaalsContact C-N 3.29Å; H376-N378 PolarHBondContact O-N 3.49Å; H376-W468 HydrophobicContact CB-CH2 4.4Å; H376-W468 AromaticContact CD2-CZ3 3.9Å; H376-W468 AromaticContact CE1-CZ3 3.77Å; H376-W468 AromaticContact CG-CH2 3.95Å; H376-W468 AromaticContact CG-CZ3 3.79Å; H376-W468 AromaticContact ND1-CH2 3.73Å; H376-W468 AromaticContact ND1-CZ3 3.71Å; H376-W468 AromaticContact NE2-CZ3 3.88Å; H376-D473 IonicContact CE1-OD1 3.74Å; H376-D473 IonicContact NE2-OD1 3.95Å; H376-D473 PolarHBondContact NE2-OD1 2.69Å; H376-D475 IonicContact CD2-OD2 3.67Å; H376-D475 IonicContact NE2-OD2 2.63Å
377	M	74.2	Confident	73.2	Confident	141 Å²	141	66.3 Å²	66.3	70%	0.695	35%	0.348	S	S	*	.	H	α-helix	trans	-70.8	-23.2	172.9	-74.3	-178.1	175.3	0	0	113.4	T373 L375	T373-M377 HydrophobicContact CG2-CE 3.81Å; T373-M377 HydrophobicContact CG2-SD 4.34Å; T373-M377 VanDerWaalsContact O-CG 3.32Å; T373-M377 WeakPolarHBondContact O-CG 3.2Å; T373-M377 PolarHBondContact O-N 3.42Å; L375-M377 VanDerWaalsContact C-N 3.27Å; L375-M377 PolarHBondContact O-N 3.07Å
378	N	77.4	Confident	71.4	Confident	90 Å²	90	67.4 Å²	67.4	48%	0.481	36%	0.357	S	S	.	.	H	α-helix	trans	-106.1	-6	-173.4	-71	-51.7	0	0	0	114.1	F374 L375 H376	F374-N378 VanDerWaalsContact CE1-ND2 3.35Å; F374-N378 WeakPolarHBondContact CE1-ND2 3.16Å; F374-N378 WeakPolarHBondContact CE2-ND2 3.31Å; F374-N378 WeakPolarHBondContact CZ-ND2 3.12Å; F374-N378 PolarHBondContact O-N 3.2Å; F374-N378 PolarHBondContact O-ND2 2.95Å; L375-N378 PolarHBondContact O-N 3.45Å; H376-N378 VanDerWaalsContact C-N 3.29Å; H376-N378 PolarHBondContact O-N 3.49Å
379	G	77	Confident	69.6	Low	26 Å²	26	71.2 Å²	71.2	27%	0.268	38%	0.382	S	S	.	.			trans	168.4	-174.7	175.5	0	0	0	0	0	112.4	L375 W468	L375-G379 PolarHBondContact O-N 3.18Å; L375-G379 VanDerWaalsContact O-N 3.07Å; G379-W468 WeakPolarHBondContact O-CH2 3.48Å; G379-W468 VanDerWaalsContact O-CZ2 3.24Å; G379-W468 WeakPolarHBondContact O-CZ2 3.27Å
380	M	76	Confident	68.2	Low	125 Å²	125	79.3 Å²	79.3	62%	0.616	41%	0.406	S	S	*	.			trans	-95.3	152.6	171.7	-56.3	-170.5	-179.7	0	0	111.4	G382 E383 W468	M380-G382 PolarHBondContact O-N 3.08Å; M380-E383 HydrophobicContact CB-CB 4.16Å; M380-E383 VanDerWaalsContact CB-OE2 3.29Å; M380-E383 WeakPolarHBondContact CB-OE2 3.41Å; M380-E383 VanDerWaalsContact CG-OE2 3.3Å; M380-E383 WeakPolarHBondContact CG-OE2 3.27Å; M380-E383 WeakPolarHBondContact O-CB 3.48Å; M380-E383 PolarHBondContact O-N 3.46Å; M380-E383 VanDerWaalsContact O-N 3.09Å; M380-W468 WeakPolarHBondContact O-CZ2 3.43Å
381	P	75.9	Confident	66.9	Low	40 Å²	40	87.6 Å²	87.6	26%	0.26	44%	0.438	S	S	.	.	T	Hydrogen-bonded Turn	trans	-51.2	130.3	173.2	-24.4	31.6	0	0	0	111.3	E383 W468	P381-E383 VanDerWaalsContact C-N 3.27Å; P381-E383 PolarHBondContact O-N 3.06Å; P381-W468 HydrophobicContact CB-CD2 4.48Å; P381-W468 HydrophobicContact CB-CE3 4.28Å; P381-W468 HydrophobicContact CB-CZ3 4.31Å; P381-W468 VanDerWaalsContact CD-CH2 3.5Å; P381-W468 HydrophobicContact CG-CE3 4Å; P381-W468 HydrophobicContact CG-CH2 3.82Å; P381-W468 HydrophobicContact CG-CZ2 4.46Å; P381-W468 HydrophobicContact CG-CZ3 3.59Å
382	G	72.5	Confident	65.9	Low	28 Å²	28	91.2 Å²	91.2	29%	0.289	46%	0.462	S	S	.	.	T	Hydrogen-bonded Turn	trans	79.5	-14.8	-179.3	0	0	0	0	0	116.7	M380 N384 W468	M380-G382 PolarHBondContact O-N 3.08Å; G382-N384 VanDerWaalsContact C-N 3.34Å; G382-N384 PolarHBondContact O-N 2.74Å; G382-W468 PolarHBondContact N-O 3.35Å
383	E	64.8	Low	65.2	Low	128 Å²	128	92.3 Å²	92.3	60%	0.598	47%	0.469	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.7	-8.4	-168.1	-153.4	174.1	-175.8	0	0	114.9	M380 P381	M380-E383 HydrophobicContact CB-CB 4.16Å; M380-E383 VanDerWaalsContact CB-OE2 3.29Å; M380-E383 WeakPolarHBondContact CB-OE2 3.41Å; M380-E383 VanDerWaalsContact CG-OE2 3.3Å; M380-E383 WeakPolarHBondContact CG-OE2 3.27Å; M380-E383 WeakPolarHBondContact O-CB 3.48Å; M380-E383 PolarHBondContact O-N 3.46Å; M380-E383 VanDerWaalsContact O-N 3.09Å; P381-E383 VanDerWaalsContact C-N 3.27Å; P381-E383 PolarHBondContact O-N 3.06Å
384	N	53.1	Low	65	Low	94 Å²	94	92 Å²	92	50%	0.503	47%	0.47	S	S	.	.	T	Hydrogen-bonded Turn	trans	-135.3	46.2	176.9	-75.5	-43.3	0	0	0	112.6	G382 E386 Q387 A388	G382-N384 VanDerWaalsContact C-N 3.34Å; G382-N384 PolarHBondContact O-N 2.74Å; N384-E386 PolarHBondContact O-N 2.73Å; N384-Q387 PolarHBondContact O-N 3.46Å; N384-A388 PolarHBondContact O-N 2.99Å
385	S	49.5	Very low	64.8	Low	45 Å²	45	92.3 Å²	92.3	32%	0.315	48%	0.478	S	S	.	.	T	Hydrogen-bonded Turn	trans	-64.8	1.1	-176.1	62.2	0	0	0	0	115.8	R390	S385-R390 PolarHBondContact O-NE 3.49Å; S385-R390 PolarHBondContact O-NH2 3.06Å
386	E	46.8	Very low	64.5	Low	193 Å²	193	95.5 Å²	95.5	90%	0.902	50%	0.501	S	S	*	.	T	Hydrogen-bonded Turn	trans	-92.2	-20.7	169.4	-66.3	-163.9	142.2	0	0	114.1	N384	N384-E386 PolarHBondContact O-N 2.73Å
387	Q	46.3	Very low	64.6	Low	175 Å²	175	95 Å²	95	82%	0.818	50%	0.503	S	S	*	.	T	Hydrogen-bonded Turn	trans	-111.8	-16.1	177.6	-69.1	-175.6	8.2	0	0	114	N384 P389	N384-Q387 PolarHBondContact O-N 3.46Å; Q387-P389 WeakPolarHBondContact O-CD 3.39Å
388	A	50.8	Low	64.8	Low	24 Å²	24	88.4 Å²	88.4	20%	0.198	47%	0.471	C	S	.	.	S	Bend	trans	-63.1	123.8	170.6	0	0	0	0	0	109.1	N384 R390	N384-A388 PolarHBondContact O-N 2.99Å; A388-R390 PolarHBondContact O-N 3.25Å
389	P	51.1	Low	65	Low	81 Å²	81	84.9 Å²	84.9	53%	0.526	45%	0.451	S	S	.	.			trans	-62.7	97.9	-179.5	22.8	-29.9	0	0	0	109.2	Q387 R391	Q387-P389 WeakPolarHBondContact O-CD 3.39Å; P389-R391 PolarHBondContact O-N 3.32Å
390	R	50.6	Low	65.2	Low	213 Å²	213	91.4 Å²	91.4	80%	0.804	47%	0.472	S	S	*	.			trans	-65.3	-5.5	173.2	-66.9	-170.7	-175.9	-167.9	0.1	112.6	S385 A388	S385-R390 PolarHBondContact O-NE 3.49Å; S385-R390 PolarHBondContact O-NH2 3.06Å; A388-R390 PolarHBondContact O-N 3.25Å
391	R	55.6	Low	65.4	Low	220 Å²	220	87.1 Å²	87.1	83%	0.83	46%	0.455	S	S	*	.	S	Bend	trans	-99.6	135	179.2	-124.7	172.7	-167.2	157.7	4.2	108.5	P389	P389-R391 PolarHBondContact O-N 3.32Å
392	C	63.5	Low	65.5	Low	76 Å²	76	90 Å²	90	51%	0.514	47%	0.473	S	S	.	.	P	Polyproline II helix	trans	-47	120.1	169.6	-58.9	0	0	0	0	108.5	S394 W462	C392-S394 PolarHBondContact O-N 3.34Å; C392-W462 PolarHBondContact SG-NE1 3.47Å
393	P	68.5	Low	66	Low	22 Å²	22	91.4 Å²	91.4	14%	0.143	47%	0.474	C	S	.	.	P	Polyproline II helix	trans	-56.4	140	175.1	23.5	-29.8	0	0	0	107.1	Y458 D461 W462	P393-Y458 VanDerWaalsContact O-CE2 3.32Å; P393-Y458 WeakPolarHBondContact O-CE2 3.25Å; P393-Y458 PolarHBondContact O-OH 3.01Å; P393-D461 VanDerWaalsContact CG-OD2 3.24Å; P393-D461 WeakPolarHBondContact CG-OD2 3.07Å; P393-W462 HydrophobicContact CG-CB 4.35Å
394	S	72.4	Confident	66.8	Low	54 Å²	54	86.9 Å²	86.9	38%	0.378	46%	0.455	S	S	.	.	P	Polyproline II helix	trans	-64.1	146	171.3	67.2	0	0	0	0	108.5	C392 C396 T397 T398	C392-S394 PolarHBondContact O-N 3.34Å; S394-C396 PolarHBondContact O-N 3.35Å; S394-T397 PolarHBondContact N-OG1 2.9Å; S394-T397 PolarHBondContact O-N 3.25Å; S394-T397 PolarHBondContact O-OG1 3.49Å; S394-T397 WeakPolarHBondContact OG-CG2 3.16Å; S394-T397 PolarHBondContact OG-N 3.23Å; S394-T397 VanDerWaalsContact OG-N 3.09Å; S394-T397 PolarHBondContact OG-OG1 3.4Å; S394-T398 PolarHBondContact O-N 2.96Å; S394-T398 VanDerWaalsContact O-N 3.13Å; S394-T398 PolarHBondContact O-OG1 2.9Å
395	P	76.6	Confident	68.4	Low	71 Å²	71	82.9 Å²	82.9	46%	0.461	43%	0.434	S	S	.	.	H	α-helix	trans	-52.8	-32	173.6	-26.9	33.3	0	0	0	112.2	T397 T398 F399 Y458	P395-T397 PolarHBondContact O-N 3.05Å; P395-T398 PolarHBondContact O-N 3.37Å; P395-F399 WeakPolarHBondContact O-CD2 3.37Å; P395-F399 PolarHBondContact O-N 2.93Å; P395-F399 VanDerWaalsContact O-N 3.15Å; P395-Y458 HydrophobicContact CB-CD2 4.19Å; P395-Y458 HydrophobicContact CB-CE2 4.24Å; P395-Y458 HydrophobicContact CG-CD2 4.06Å; P395-Y458 HydrophobicContact CG-CE2 3.68Å
396	C	76.3	Confident	70.2	Confident	84 Å²	84	80.9 Å²	80.9	57%	0.568	42%	0.42	S	S	*	.	H	α-helix	trans	-63.3	-40	174.9	-68.4	0	0	0	0	112.8	S394 F400	S394-C396 PolarHBondContact O-N 3.35Å; C396-F400 WeakPolarHBondContact O-CA 3.27Å; C396-F400 VanDerWaalsContact O-CB 3.26Å; C396-F400 WeakPolarHBondContact O-CB 3.49Å; C396-F400 PolarHBondContact O-N 2.85Å
397	T	78	Confident	72.1	Confident	65 Å²	65	75 Å²	75	40%	0.399	39%	0.389	S	S	.	.	H	α-helix	trans	-68.7	-39.7	175.9	43.7	0	0	0	0	111.4	S394 P395 F399 S401 S406	S394-T397 PolarHBondContact N-OG1 2.9Å; S394-T397 PolarHBondContact O-N 3.25Å; S394-T397 PolarHBondContact O-OG1 3.49Å; S394-T397 WeakPolarHBondContact OG-CG2 3.16Å; S394-T397 PolarHBondContact OG-N 3.23Å; S394-T397 VanDerWaalsContact OG-N 3.09Å; S394-T397 PolarHBondContact OG-OG1 3.4Å; P395-T397 PolarHBondContact O-N 3.05Å; T397-F399 PolarHBondContact O-N 3.14Å; T397-S401 WeakPolarHBondContact O-CB 3.47Å; T397-S401 PolarHBondContact O-N 3.45Å; T397-S406 PolarHBondContact O-OG 3.07Å; T397-S406 VanDerWaalsContact O-OG 3.06Å
398	T	77.5	Confident	74.1	Confident	2 Å²	2	66.6 Å²	66.6	1%	0.012	35%	0.35	C	S	.	.	H	α-helix	trans	-65.2	-35.4	-179.7	-53.9	0	0	0	0	113.3	S394 P395 S406 D461	S394-T398 PolarHBondContact O-N 2.96Å; S394-T398 VanDerWaalsContact O-N 3.13Å; S394-T398 PolarHBondContact O-OG1 2.9Å; P395-T398 PolarHBondContact O-N 3.37Å; T398-S406 VanDerWaalsContact O-CA 3.32Å; T398-S406 WeakPolarHBondContact O-CA 3.48Å; T398-S406 WeakPolarHBondContact O-CB 3.29Å; T398-S406 PolarHBondContact O-OG 3.28Å; T398-S406 VanDerWaalsContact O-OG 3.05Å; T398-D461 WeakPolarHBondContact CB-OD2 3.28Å; T398-D461 HydrophobicContact CG2-CB 3.48Å; T398-D461 VanDerWaalsContact CG2-CB 3.48Å; T398-D461 WeakPolarHBondContact CG2-OD2 2.8Å; T398-D461 PolarHBondContact OG1-OD2 2.96Å
399	F	81.7	Confident	76	Confident	16 Å²	16	65.5 Å²	65.5	7%	0.07	34%	0.341	C	S	.	.	H	α-helix	trans	-103.5	-28.3	-176.5	-70	-76	0	0	0	114.2	P395 T397 A409 R410 L454 L457	P395-F399 WeakPolarHBondContact O-CD2 3.37Å; P395-F399 PolarHBondContact O-N 2.93Å; P395-F399 VanDerWaalsContact O-N 3.15Å; T397-F399 PolarHBondContact O-N 3.14Å; F399-A409 HydrophobicContact CD1-CB 4.18Å; F399-A409 HydrophobicContact CE1-CB 4.14Å; F399-R410 WeakPolarHBondContact O-CD 3.41Å; F399-R410 WeakPolarHBondContact O-CG 3.25Å; F399-R410 PolarHBondContact O-NH1 2.87Å; F399-L454 HydrophobicContact CD2-CD1 4.26Å; F399-L454 HydrophobicContact CE1-CD1 4.21Å; F399-L454 HydrophobicContact CE2-CD1 3.62Å; F399-L454 HydrophobicContact CZ-CD1 3.6Å; F399-L454 HydrophobicContact CZ-CG 4.48Å; F399-L457 HydrophobicContact CE1-CB 4.01Å; F399-L457 HydrophobicContact CE1-CD1 3.99Å; F399-L457 HydrophobicContact CZ-CB 3.78Å; F399-L457 HydrophobicContact CZ-CD1 4.47Å
400	F	81.6	Confident	78	Confident	163 Å²	163	65.1 Å²	65.1	72%	0.715	33%	0.329	S	S	*	.	H	α-helix	trans	-113.7	2.2	-170.9	-58.8	-86.2	0	0	0	114.3	C396	C396-F400 WeakPolarHBondContact O-CA 3.27Å; C396-F400 VanDerWaalsContact O-CB 3.26Å; C396-F400 WeakPolarHBondContact O-CB 3.49Å; C396-F400 PolarHBondContact O-N 2.85Å
401	S	80.7	Confident	79.9	Confident	35 Å²	35	55.8 Å²	55.8	25%	0.245	30%	0.296	C	S	.	.	S	Bend	trans	-74.4	150.9	174.3	174.3	0	0	0	0	111.4	T397 D403 S406 R410	T397-S401 WeakPolarHBondContact O-CB 3.47Å; T397-S401 PolarHBondContact O-N 3.45Å; S401-D403 WeakPolarHBondContact CB-OD1 3.17Å; S401-D403 PolarHBondContact O-N 3.49Å; S401-D403 PolarHBondContact OG-OD1 2.6Å; S401-S406 WeakPolarHBondContact O-CB 3.21Å; S401-R410 PolarHBondContact O-NH1 2.89Å
402	P	78.6	Confident	81.6	Confident	100 Å²	100	45.3 Å²	45.3	65%	0.649	26%	0.256	S	S	*	.	S	Bend	trans	-75.5	-3.9	-178.3	29.1	-36.7	0	0	0	114.6	R407	P402-R407 PolarHBondContact O-NE 3.02Å; P402-R407 PolarHBondContact O-NH2 3.31Å
403	D	83	Confident	83.1	Confident	58 Å²	58	44.5 Å²	44.5	31%	0.31	24%	0.244	S	C	.	.	S	Bend	trans	-66.7	164.1	-179	66.6	-80.7	0	0	0	113.4	S401 N405 S406 R407	S401-D403 WeakPolarHBondContact CB-OD1 3.17Å; S401-D403 PolarHBondContact O-N 3.49Å; S401-D403 PolarHBondContact OG-OD1 2.6Å; D403-N405 VanDerWaalsContact C-N 3.33Å; D403-N405 PolarHBondContact O-N 3.04Å; D403-N405 WeakPolarHBondContact OD2-CA 3.41Å; D403-N405 WeakPolarHBondContact OD2-CB 3.47Å; D403-N405 PolarHBondContact OD2-N 3.4Å; D403-N405 VanDerWaalsContact OD2-N 3.08Å; D403-S406 VanDerWaalsContact CG-OG 3.26Å; D403-S406 VanDerWaalsContact OD1-CB 3.28Å; D403-S406 WeakPolarHBondContact OD1-CB 3.12Å; D403-S406 PolarHBondContact OD1-OG 3Å; D403-S406 PolarHBondContact OD2-N 3.39Å; D403-S406 PolarHBondContact OD2-OG 3.36Å; D403-R407 VanDerWaalsContact O-CG 3.29Å; D403-R407 WeakPolarHBondContact O-CG 3.49Å; D403-R407 PolarHBondContact O-N 2.74Å
404	V	81.8	Confident	84.3	Confident	33 Å²	33	49.4 Å²	49.4	20%	0.2	27%	0.268	C	S	.	.	H	α-helix	trans	-65.8	-35.8	-175.6	179.8	0	0	0	0	111.7	R407 S408	V404-R407 WeakPolarHBondContact O-CB 3.21Å; V404-R407 PolarHBondContact O-N 2.87Å; V404-S408 WeakPolarHBondContact O-CB 3.34Å; V404-S408 PolarHBondContact O-N 2.94Å
405	N	85.1	Confident	85.3	Confident	10 Å²	10	47.8 Å²	47.8	5%	0.053	26%	0.256	C	S	.	.	H	α-helix	trans	-70.8	-41.8	-178.7	-64.8	-28	0	0	0	111.2	Q367 I371 D403 S408 A409	Q367-N405 PolarHBondContact NE2-O 3.03Å; I371-N405 HydrophobicContact CG1-CB 4.11Å; D403-N405 VanDerWaalsContact C-N 3.33Å; D403-N405 PolarHBondContact O-N 3.04Å; D403-N405 WeakPolarHBondContact OD2-CA 3.41Å; D403-N405 WeakPolarHBondContact OD2-CB 3.47Å; D403-N405 PolarHBondContact OD2-N 3.4Å; D403-N405 VanDerWaalsContact OD2-N 3.08Å; N405-S408 VanDerWaalsContact O-CB 3.32Å; N405-S408 WeakPolarHBondContact O-CB 3.19Å; N405-S408 PolarHBondContact O-N 3.41Å; N405-A409 PolarHBondContact O-N 2.97Å
406	S	88	Confident	86.2	Confident	4 Å²	4	44.4 Å²	44.4	3%	0.028	23%	0.234	C	C	.	.	H	α-helix	trans	-65.5	-38	173.1	-63.1	0	0	0	0	112.2	T397 T398 S401 D403 A409 R410	T397-S406 PolarHBondContact O-OG 3.07Å; T397-S406 VanDerWaalsContact O-OG 3.06Å; T398-S406 VanDerWaalsContact O-CA 3.32Å; T398-S406 WeakPolarHBondContact O-CA 3.48Å; T398-S406 WeakPolarHBondContact O-CB 3.29Å; T398-S406 PolarHBondContact O-OG 3.28Å; T398-S406 VanDerWaalsContact O-OG 3.05Å; S401-S406 WeakPolarHBondContact O-CB 3.21Å; D403-S406 VanDerWaalsContact CG-OG 3.26Å; D403-S406 VanDerWaalsContact OD1-CB 3.28Å; D403-S406 WeakPolarHBondContact OD1-CB 3.12Å; D403-S406 PolarHBondContact OD1-OG 3Å; D403-S406 PolarHBondContact OD2-N 3.39Å; D403-S406 PolarHBondContact OD2-OG 3.36Å; S406-A409 PolarHBondContact O-N 2.91Å; S406-R410 WeakPolarHBondContact O-CG 3.31Å; S406-R410 PolarHBondContact O-N 3.42Å; S406-R410 PolarHBondContact O-NH1 3.42Å
407	R	87.4	Confident	87.2	Confident	68 Å²	68	43.1 Å²	43.1	26%	0.257	22%	0.223	S	C	.	.	H	α-helix	trans	-60.5	-45.7	171.4	-74	169.7	-167.1	-149	-3.3	111.3	P402 D403 V404 R410 V411	P402-R407 PolarHBondContact O-NE 3.02Å; P402-R407 PolarHBondContact O-NH2 3.31Å; D403-R407 VanDerWaalsContact O-CG 3.29Å; D403-R407 WeakPolarHBondContact O-CG 3.49Å; D403-R407 PolarHBondContact O-N 2.74Å; V404-R407 WeakPolarHBondContact O-CB 3.21Å; V404-R407 PolarHBondContact O-N 2.87Å; R407-R410 PolarHBondContact O-N 3.34Å; R407-V411 WeakPolarHBondContact O-CG2 3.26Å; R407-V411 PolarHBondContact O-N 3.36Å
408	S	86.6	Confident	88.1	Confident	0 Å²	0	43.2 Å²	43.2	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-58.7	-50.5	176.5	-171.2	0	0	0	0	111.3	Q367 R370 V404 N405 R410 V411 L412	Q367-S408 PolarHBondContact OE1-OG 3.32Å; R370-S408 WeakPolarHBondContact CD-OG 3.09Å; R370-S408 PolarHBondContact NH1-OG 3.48Å; V404-S408 WeakPolarHBondContact O-CB 3.34Å; V404-S408 PolarHBondContact O-N 2.94Å; N405-S408 VanDerWaalsContact O-CB 3.32Å; N405-S408 WeakPolarHBondContact O-CB 3.19Å; N405-S408 PolarHBondContact O-N 3.41Å; S408-R410 VanDerWaalsContact C-N 3.31Å; S408-R410 PolarHBondContact O-N 3.38Å; S408-V411 PolarHBondContact O-N 2.85Å; S408-V411 VanDerWaalsContact O-N 3.1Å; S408-L412 WeakPolarHBondContact O-CG 3.19Å; S408-L412 PolarHBondContact O-N 2.76Å
409	A	91.3	Very high	88.9	Confident	0 Å²	0	43.2 Å²	43.2	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-57.2	-42.8	178.6	0	0	0	0	0	112	F399 N405 S406 L412 F413 L457	F399-A409 HydrophobicContact CD1-CB 4.18Å; F399-A409 HydrophobicContact CE1-CB 4.14Å; N405-A409 PolarHBondContact O-N 2.97Å; S406-A409 PolarHBondContact O-N 2.91Å; A409-L412 PolarHBondContact O-N 3.41Å; A409-F413 VanDerWaalsContact O-CB 3.26Å; A409-F413 WeakPolarHBondContact O-CB 3.19Å; A409-F413 PolarHBondContact O-N 2.95Å; A409-L457 WeakPolarHBondContact O-CD1 3.38Å
410	R	93.3	Very high	89.6	Confident	73 Å²	73	42.5 Å²	42.5	28%	0.275	22%	0.222	S	C	.	.	H	α-helix	trans	-62.5	-44.1	175.3	-72.4	-170.3	-62	-88.7	8	112.8	F399 S401 S406 R407 S408 F413 L414	F399-R410 WeakPolarHBondContact O-CD 3.41Å; F399-R410 WeakPolarHBondContact O-CG 3.25Å; F399-R410 PolarHBondContact O-NH1 2.87Å; S401-R410 PolarHBondContact O-NH1 2.89Å; S406-R410 WeakPolarHBondContact O-CG 3.31Å; S406-R410 PolarHBondContact O-N 3.42Å; S406-R410 PolarHBondContact O-NH1 3.42Å; R407-R410 PolarHBondContact O-N 3.34Å; S408-R410 VanDerWaalsContact C-N 3.31Å; S408-R410 PolarHBondContact O-N 3.38Å; R410-F413 PolarHBondContact O-N 3.36Å; R410-L414 WeakPolarHBondContact O-CB 3.42Å; R410-L414 VanDerWaalsContact O-CG 3.25Å; R410-L414 WeakPolarHBondContact O-CG 3.45Å; R410-L414 PolarHBondContact O-N 2.78Å
411	V	90.8	Very high	90.3	Very high	17 Å²	17	38.6 Å²	38.6	10%	0.103	21%	0.208	C	C	.	.	H	α-helix	trans	-63.2	-46.2	179.2	171	0	0	0	0	110.5	I98 R407 S408 L414 L415	I98-V411 HydrophobicContact CB-CG1 4.49Å; I98-V411 HydrophobicContact CG2-CB 4.34Å; I98-V411 HydrophobicContact CG2-CG1 4.08Å; R407-V411 WeakPolarHBondContact O-CG2 3.26Å; R407-V411 PolarHBondContact O-N 3.36Å; S408-V411 PolarHBondContact O-N 2.85Å; S408-V411 VanDerWaalsContact O-N 3.1Å; V411-L414 PolarHBondContact O-N 3.23Å; V411-L415 PolarHBondContact O-N 3.29Å; V411-L415 VanDerWaalsContact O-N 3.1Å
412	L	91.8	Very high	91	Very high	1 Å²	1	39.8 Å²	39.8	1%	0.005	21%	0.214	C	C	.	.	H	α-helix	trans	-63.4	-42.4	178.1	-64.8	173.6	0	0	0	111.7	V102 L363 V366 Q367 S408 A409 L415 L457	V102-L412 HydrophobicContact CG1-CD2 3.76Å; V102-L412 HydrophobicContact CG2-CD2 4.41Å; L363-L412 HydrophobicContact CD2-CB 4.18Å; L363-L412 HydrophobicContact CD2-CD2 3.68Å; L363-L412 HydrophobicContact CD2-CG 4.48Å; V366-L412 HydrophobicContact CG1-CD1 4.47Å; V366-L412 HydrophobicContact CG1-CD2 4.26Å; Q367-L412 HydrophobicContact CB-CD1 3.68Å; Q367-L412 HydrophobicContact CG-CD1 4.39Å; S408-L412 WeakPolarHBondContact O-CG 3.19Å; S408-L412 PolarHBondContact O-N 2.76Å; A409-L412 PolarHBondContact O-N 3.41Å; L412-L415 WeakPolarHBondContact O-CB 3.42Å; L412-L415 PolarHBondContact O-N 3.4Å; L412-L457 HydrophobicContact CB-CD1 4.42Å; L412-L457 HydrophobicContact CB-CD2 4.47Å; L412-L457 HydrophobicContact CD1-CD2 4.18Å
413	F	94.5	Very high	91.8	Very high	58 Å²	58	35 Å²	35	25%	0.254	18%	0.183	S	C	.	.	H	α-helix	trans	-64.1	-41.3	176.2	-175.5	-103	0	0	0	112.5	A409 R410 L415 V416 L450 V453 L454 L457	A409-F413 VanDerWaalsContact O-CB 3.26Å; A409-F413 WeakPolarHBondContact O-CB 3.19Å; A409-F413 PolarHBondContact O-N 2.95Å; R410-F413 PolarHBondContact O-N 3.36Å; F413-L415 VanDerWaalsContact C-N 3.26Å; F413-L415 PolarHBondContact O-N 3.45Å; F413-V416 WeakPolarHBondContact O-CB 3.23Å; F413-V416 VanDerWaalsContact O-CG2 3.3Å; F413-V416 WeakPolarHBondContact O-CG2 3.46Å; F413-V416 PolarHBondContact O-N 2.92Å; F413-L450 HydrophobicContact CE1-CD2 4.26Å; F413-L450 HydrophobicContact CE2-CB 4.41Å; F413-L450 HydrophobicContact CE2-CD2 3.83Å; F413-L450 HydrophobicContact CZ-CB 4.46Å; F413-L450 HydrophobicContact CZ-CD2 3.69Å; F413-V453 HydrophobicContact CD2-CG1 4.36Å; F413-L454 HydrophobicContact CE2-CB 3.93Å; F413-L454 HydrophobicContact CE2-CD1 4.14Å; F413-L454 HydrophobicContact CZ-CD1 4.49Å; F413-L457 HydrophobicContact CB-CD1 3.98Å
414	L	94	Very high	92.4	Very high	125 Å²	125	32.4 Å²	32.4	65%	0.654	17%	0.169	S	C	*	.	H	α-helix	trans	-67	-26.8	177.1	-74.5	171.6	0	0	0	113	R410 V411 V416 P418	R410-L414 WeakPolarHBondContact O-CB 3.42Å; R410-L414 VanDerWaalsContact O-CG 3.25Å; R410-L414 WeakPolarHBondContact O-CG 3.45Å; R410-L414 PolarHBondContact O-N 2.78Å; V411-L414 PolarHBondContact O-N 3.23Å; L414-V416 VanDerWaalsContact C-N 3.28Å; L414-V416 PolarHBondContact O-N 3.21Å; L414-P418 WeakPolarHBondContact O-CD 3.33Å
415	L	93.1	Very high	92.9	Very high	21 Å²	21	38.6 Å²	38.6	11%	0.11	19%	0.19	C	C	.	.	H	α-helix	trans	-72.8	-21.1	178.9	-171.1	60.5	0	0	0	113	V102 L103 F106 L363 V411 L412 F413 V417 P418 G419	V102-L415 HydrophobicContact CG1-CD2 4.06Å; L103-L415 HydrophobicContact CD1-CD1 3.61Å; F106-L415 HydrophobicContact CB-CD2 3.71Å; F106-L415 HydrophobicContact CD1-CD1 4.05Å; F106-L415 HydrophobicContact CD1-CD2 3.58Å; F106-L415 HydrophobicContact CD1-CG 3.68Å; F106-L415 HydrophobicContact CD2-CD2 3.71Å; F106-L415 HydrophobicContact CD2-CG 4.21Å; F106-L415 HydrophobicContact CE1-CD1 4.13Å; F106-L415 HydrophobicContact CE1-CD2 4.07Å; F106-L415 HydrophobicContact CE1-CG 3.67Å; F106-L415 HydrophobicContact CE2-CD2 4.14Å; F106-L415 HydrophobicContact CE2-CG 4.16Å; F106-L415 HydrophobicContact CG-CD2 3.38Å; F106-L415 HydrophobicContact CG-CG 3.96Å; F106-L415 HydrophobicContact CZ-CD2 4.33Å; F106-L415 HydrophobicContact CZ-CG 3.92Å; L363-L415 HydrophobicContact CD2-CD2 4.42Å; V411-L415 PolarHBondContact O-N 3.29Å; V411-L415 VanDerWaalsContact O-N 3.1Å; L412-L415 WeakPolarHBondContact O-CB 3.42Å; L412-L415 PolarHBondContact O-N 3.4Å; F413-L415 VanDerWaalsContact C-N 3.26Å; F413-L415 PolarHBondContact O-N 3.45Å; L415-V417 PolarHBondContact O-N 3.07Å; L415-P418 WeakPolarHBondContact O-CD 3.26Å; L415-P418 WeakPolarHBondContact O-CG 3.4Å; L415-G419 PolarHBondContact O-N 3.4Å
416	V	96	Very high	93.3	Very high	0 Å²	0	39.5 Å²	39.5	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-56.2	-53.2	-179.7	179.1	0	0	0	0	111	L363 F413 L414 G419 H420 A449 L450 V453	L363-V416 HydrophobicContact CD1-CG2 3.73Å; F413-V416 WeakPolarHBondContact O-CB 3.23Å; F413-V416 VanDerWaalsContact O-CG2 3.3Å; F413-V416 WeakPolarHBondContact O-CG2 3.46Å; F413-V416 PolarHBondContact O-N 2.92Å; L414-V416 VanDerWaalsContact C-N 3.28Å; L414-V416 PolarHBondContact O-N 3.21Å; V416-G419 PolarHBondContact O-N 3.05Å; V416-H420 VanDerWaalsContact CG1-CD2 3.5Å; V416-H420 WeakPolarHBondContact CG1-CD2 3.45Å; V416-H420 WeakPolarHBondContact O-CB 3.21Å; V416-H420 PolarHBondContact O-CD2 2.88Å; V416-H420 VanDerWaalsContact O-CD2 3.23Å; V416-H420 PolarHBondContact O-N 3.32Å; V416-A449 HydrophobicContact CG1-CB 4.2Å; V416-L450 HydrophobicContact CB-CD2 4.06Å; V416-L450 HydrophobicContact CG1-CD2 3.89Å; V416-L450 HydrophobicContact CG1-CG 4.31Å; V416-V453 HydrophobicContact CG1-CG2 4.49Å; V416-V453 HydrophobicContact CG2-CB 3.92Å; V416-V453 HydrophobicContact CG2-CG1 3.7Å; V416-V453 HydrophobicContact CG2-CG2 3.84Å
417	V	96.4	Very high	93.5	Very high	56 Å²	56	39.4 Å²	39.4	34%	0.339	20%	0.195	S	C	.	.	H	α-helix	trans	-60.2	-59	-175.5	-178.3	0	0	0	0	113	L415 G419 L421 M446 L450	L415-V417 PolarHBondContact O-N 3.07Å; V417-G419 VanDerWaalsContact C-N 3.27Å; V417-G419 PolarHBondContact O-N 3.23Å; V417-L421 HydrophobicContact CG1-CD1 4.02Å; V417-L421 WeakPolarHBondContact O-CB 3.43Å; V417-L421 VanDerWaalsContact O-CG 3.27Å; V417-L421 WeakPolarHBondContact O-CG 3.18Å; V417-L421 PolarHBondContact O-N 2.89Å; V417-M446 HydrophobicContact CB-SD 4.24Å; V417-M446 HydrophobicContact CG1-CE 4.34Å; V417-M446 HydrophobicContact CG1-SD 4.25Å; V417-M446 HydrophobicContact CG2-SD 4.08Å; V417-L450 HydrophobicContact CG2-CD1 4.19Å; V417-L450 HydrophobicContact CG2-CD2 3.88Å; V417-L450 HydrophobicContact CG2-CG 4.4Å
418	P	96	Very high	93.6	Very high	68 Å²	68	39.1 Å²	39.1	44%	0.442	20%	0.203	S	C	.	.	H	α-helix	trans	-63.1	-35.8	179.9	25.7	-34.1	0	0	0	112	L414 L415 V422	L414-P418 WeakPolarHBondContact O-CD 3.33Å; L415-P418 WeakPolarHBondContact O-CD 3.26Å; L415-P418 WeakPolarHBondContact O-CG 3.4Å; P418-V422 WeakPolarHBondContact O-CG2 3.21Å; P418-V422 PolarHBondContact O-N 2.91Å; P418-V422 VanDerWaalsContact O-N 3.11Å
419	G	95.6	Very high	93.8	Very high	2 Å²	2	42.9 Å²	42.9	2%	0.021	23%	0.229	C	C	.	.	H	α-helix	trans	-59.9	-58.4	176.7	0	0	0	0	0	113.2	F106 L415 V416 V417 L421 V422 F423	F106-G419 VanDerWaalsContact CE1-CA 3.49Å; L415-G419 PolarHBondContact O-N 3.4Å; V416-G419 PolarHBondContact O-N 3.05Å; V417-G419 VanDerWaalsContact C-N 3.27Å; V417-G419 PolarHBondContact O-N 3.23Å; G419-L421 VanDerWaalsContact C-N 3.28Å; G419-L421 PolarHBondContact O-N 3.41Å; G419-V422 WeakPolarHBondContact O-CB 3.32Å; G419-V422 PolarHBondContact O-N 3.35Å; G419-V422 VanDerWaalsContact O-N 3.1Å; G419-F423 WeakPolarHBondContact O-CD2 3.4Å; G419-F423 WeakPolarHBondContact O-CE2 3.37Å; G419-F423 WeakPolarHBondContact O-CG 3.31Å; G419-F423 PolarHBondContact O-N 3.37Å
420	H	96.3	Very high	93.7	Very high	0 Å²	0	47.9 Å²	47.9	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-61.5	-35.5	179.4	-82.2	-80.2	0	0	0	112.3	V359 V416 V422 F423 L424 Y445 M446	V359-H420 WeakPolarHBondContact CG1-NE2 3.49Å; V416-H420 VanDerWaalsContact CG1-CD2 3.5Å; V416-H420 WeakPolarHBondContact CG1-CD2 3.45Å; V416-H420 WeakPolarHBondContact O-CB 3.21Å; V416-H420 PolarHBondContact O-CD2 2.88Å; V416-H420 VanDerWaalsContact O-CD2 3.23Å; V416-H420 PolarHBondContact O-N 3.32Å; H420-V422 PolarHBondContact O-N 3.41Å; H420-F423 PolarHBondContact O-N 3.03Å; H420-L424 VanDerWaalsContact O-CB 3.32Å; H420-L424 WeakPolarHBondContact O-CB 3.35Å; H420-L424 WeakPolarHBondContact O-CG 3.09Å; H420-L424 PolarHBondContact O-N 3.48Å; H420-Y445 HydrophobicContact CB-CE1 4.04Å; H420-Y445 PolarHBondContact CE1-OH 3.5Å; H420-Y445 AromaticContact CG-CE1 3.96Å; H420-Y445 AromaticContact ND1-CE1 3.41Å; H420-Y445 WeakPolarHBondContact ND1-CE1 3.37Å; H420-Y445 AromaticContact ND1-CZ 3.56Å; H420-Y445 PolarHBondContact ND1-OH 2.99Å; H420-M446 HydrophobicContact CB-CE 3.84Å; H420-M446 HydrophobicContact CB-SD 4.18Å
421	L	96.1	Very high	93.2	Very high	81 Å²	81	53 Å²	53	42%	0.424	28%	0.281	S	S	.	.	H	α-helix	trans	-61.8	-42.1	173.9	-72.3	174.7	0	0	0	112.3	V417 G419 Y425 I442 M446	V417-L421 HydrophobicContact CG1-CD1 4.02Å; V417-L421 WeakPolarHBondContact O-CB 3.43Å; V417-L421 VanDerWaalsContact O-CG 3.27Å; V417-L421 WeakPolarHBondContact O-CG 3.18Å; V417-L421 PolarHBondContact O-N 2.89Å; G419-L421 VanDerWaalsContact C-N 3.28Å; G419-L421 PolarHBondContact O-N 3.41Å; L421-Y425 VanDerWaalsContact O-CB 3.26Å; L421-Y425 WeakPolarHBondContact O-CB 3.06Å; L421-Y425 PolarHBondContact O-N 2.81Å; L421-I442 HydrophobicContact CD2-CG2 4.12Å; L421-M446 HydrophobicContact CD2-CE 3.83Å; L421-M446 HydrophobicContact CG-CE 3.76Å
422	V	95.8	Very high	92.5	Very high	60 Å²	60	52.5 Å²	52.5	36%	0.364	28%	0.279	S	S	.	.	H	α-helix	trans	-64	-43.2	174.9	170.8	0	0	0	0	110.9	F111 P418 G419 H420 Y425 T426	F111-V422 HydrophobicContact CE1-CG1 4.34Å; F111-V422 HydrophobicContact CZ-CG1 3.94Å; P418-V422 WeakPolarHBondContact O-CG2 3.21Å; P418-V422 PolarHBondContact O-N 2.91Å; P418-V422 VanDerWaalsContact O-N 3.11Å; G419-V422 WeakPolarHBondContact O-CB 3.32Å; G419-V422 PolarHBondContact O-N 3.35Å; G419-V422 VanDerWaalsContact O-N 3.1Å; H420-V422 PolarHBondContact O-N 3.41Å; V422-Y425 PolarHBondContact O-N 2.91Å; V422-T426 WeakPolarHBondContact O-CB 3.35Å; V422-T426 PolarHBondContact O-N 3.31Å; V422-T426 PolarHBondContact O-OG1 3.1Å
423	F	95.3	Very high	91.4	Very high	0 Å²	0	52.4 Å²	52.4	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-66.9	-44.1	180	-55.4	-32.8	0	0	0	112.1	F106 L107 G110 V114 V355 V359 G419 H420 T426 I427	F106-F423 HydrophobicContact CD1-CZ 4.32Å; F106-F423 AromaticContact CE1-CE2 3.93Å; F106-F423 HydrophobicContact CE1-CE2 3.93Å; F106-F423 AromaticContact CE1-CZ 3.8Å; F106-F423 HydrophobicContact CE1-CZ 3.8Å; F106-F423 AromaticContact CZ-CE2 3.88Å; F106-F423 HydrophobicContact CZ-CE2 3.88Å; F106-F423 HydrophobicContact CZ-CZ 4.2Å; L107-F423 HydrophobicContact CD2-CE1 4.1Å; L107-F423 HydrophobicContact CD2-CZ 4.21Å; G110-F423 VanDerWaalsContact CA-CZ 3.47Å; V114-F423 HydrophobicContact CG2-CB 3.64Å; V114-F423 HydrophobicContact CG2-CD1 4.15Å; V114-F423 HydrophobicContact CG2-CG 4.06Å; V355-F423 HydrophobicContact CG1-CB 3.97Å; V355-F423 HydrophobicContact CG1-CD2 4.11Å; V355-F423 HydrophobicContact CG1-CG 4.36Å; V359-F423 HydrophobicContact CG2-CD2 3.86Å; V359-F423 HydrophobicContact CG2-CE2 3.59Å; G419-F423 WeakPolarHBondContact O-CD2 3.4Å; G419-F423 WeakPolarHBondContact O-CE2 3.37Å; G419-F423 WeakPolarHBondContact O-CG 3.31Å; G419-F423 PolarHBondContact O-N 3.37Å; H420-F423 PolarHBondContact O-N 3.03Å; F423-T426 WeakPolarHBondContact O-CB 3.42Å; F423-T426 PolarHBondContact O-N 3.31Å; F423-I427 WeakPolarHBondContact O-CG1 3.5Å; F423-I427 PolarHBondContact O-N 2.93Å
424	L	94.2	Very high	90.1	Very high	3 Å²	3	54.1 Å²	54.1	2%	0.016	29%	0.287	C	S	.	.	H	α-helix	trans	-61	-47.1	174	-72.5	178.6	0	0	0	111.4	F352 H420 T426 I427 S428 L437 F441 I442 Y445	F352-L424 HydrophobicContact CD1-CD2 3.76Å; F352-L424 HydrophobicContact CE1-CD2 3.47Å; F352-L424 VanDerWaalsContact CE1-CD2 3.47Å; H420-L424 VanDerWaalsContact O-CB 3.32Å; H420-L424 WeakPolarHBondContact O-CB 3.35Å; H420-L424 WeakPolarHBondContact O-CG 3.09Å; H420-L424 PolarHBondContact O-N 3.48Å; L424-T426 PolarHBondContact O-N 3.43Å; L424-I427 PolarHBondContact O-N 3.37Å; L424-I427 VanDerWaalsContact O-N 3.17Å; L424-S428 PolarHBondContact O-N 3.3Å; L424-L437 HydrophobicContact CB-CD1 4.17Å; L424-L437 HydrophobicContact CD2-CD2 4.36Å; L424-L437 WeakPolarHBondContact O-CD1 3.29Å; L424-F441 HydrophobicContact CD2-CE1 4.31Å; L424-I442 HydrophobicContact CD1-CG1 4.37Å; L424-I442 HydrophobicContact CD1-CG2 4.46Å; L424-Y445 HydrophobicContact CD1-CD1 3.62Å; L424-Y445 HydrophobicContact CD1-CE1 3.83Å; L424-Y445 HydrophobicContact CD1-CG 4.4Å; L424-Y445 HydrophobicContact CD2-CD1 4Å; L424-Y445 HydrophobicContact CD2-CD2 4.5Å; L424-Y445 HydrophobicContact CD2-CE1 3.78Å; L424-Y445 HydrophobicContact CD2-CE2 4.34Å; L424-Y445 HydrophobicContact CD2-CG 4.34Å; L424-Y445 HydrophobicContact CG-CD1 4.12Å; L424-Y445 HydrophobicContact CG-CE1 3.86Å
425	Y	93	Very high	88.8	Confident	163 Å²	163	49.7 Å²	49.7	64%	0.639	27%	0.265	S	S	*	.	H	α-helix	trans	-58	-40.9	176	-180	-98.7	0	0	0	111.6	L421 V422 S428 C429	L421-Y425 VanDerWaalsContact O-CB 3.26Å; L421-Y425 WeakPolarHBondContact O-CB 3.06Å; L421-Y425 PolarHBondContact O-N 2.81Å; V422-Y425 PolarHBondContact O-N 2.91Å; Y425-S428 WeakPolarHBondContact O-CB 3.24Å; Y425-S428 PolarHBondContact O-N 2.89Å; Y425-C429 WeakPolarHBondContact CE1-SG 3.28Å; Y425-C429 VanDerWaalsContact CZ-SG 3.52Å; Y425-C429 PolarHBondContact O-N 3.35Å; Y425-C429 PolarHBondContact O-SG 3.15Å; Y425-C429 VanDerWaalsContact O-SG 3.36Å
426	T	93.2	Very high	87.9	Confident	29 Å²	29	52 Å²	52	18%	0.178	28%	0.28	C	S	.	.	H	α-helix	trans	-62.5	-45.3	176.4	-54.8	0	0	0	0	111.6	F111 V114 V422 F423 L424 S428 C429 M430	F111-T426 HydrophobicContact CD1-CG2 4.38Å; F111-T426 HydrophobicContact CE1-CG2 4.18Å; V114-T426 HydrophobicContact CG1-CG2 4.1Å; V422-T426 WeakPolarHBondContact O-CB 3.35Å; V422-T426 PolarHBondContact O-N 3.31Å; V422-T426 PolarHBondContact O-OG1 3.1Å; F423-T426 WeakPolarHBondContact O-CB 3.42Å; F423-T426 PolarHBondContact O-N 3.31Å; L424-T426 PolarHBondContact O-N 3.43Å; T426-S428 VanDerWaalsContact C-N 3.3Å; T426-S428 PolarHBondContact O-N 3.23Å; T426-C429 PolarHBondContact O-N 3.28Å; T426-M430 HydrophobicContact CG2-SD 4.08Å; T426-M430 WeakPolarHBondContact O-CG 3.23Å; T426-M430 PolarHBondContact O-N 2.91Å
427	I	92.3	Very high	87.2	Confident	2 Å²	2	54.1 Å²	54.1	1%	0.01	29%	0.291	C	S	.	.	H	α-helix	trans	-58.4	-44	174.8	-67.7	166.8	0	0	0	110.6	V114 V351 F352 V355 F423 L424 C429 M430 Q431 G432	V114-I427 HydrophobicContact CG1-CG1 3.82Å; V351-I427 HydrophobicContact CG1-CG2 4.01Å; V351-I427 HydrophobicContact CG2-CD1 4.23Å; V351-I427 HydrophobicContact CG2-CG1 4.21Å; V351-I427 HydrophobicContact CG2-CG2 3.89Å; F352-I427 HydrophobicContact CD1-CD1 3.8Å; F352-I427 HydrophobicContact CE1-CD1 3.79Å; F352-I427 HydrophobicContact CE1-CG2 4.13Å; F352-I427 HydrophobicContact CZ-CG2 4.36Å; V355-I427 HydrophobicContact CG2-CD1 4.18Å; F423-I427 WeakPolarHBondContact O-CG1 3.5Å; F423-I427 PolarHBondContact O-N 2.93Å; L424-I427 PolarHBondContact O-N 3.37Å; L424-I427 VanDerWaalsContact O-N 3.17Å; I427-C429 PolarHBondContact O-N 3.04Å; I427-M430 CarbonylContact O-C 3.43Å; I427-M430 PolarHBondContact O-N 3.31Å; I427-Q431 PolarHBondContact O-N 2.69Å; I427-Q431 VanDerWaalsContact O-N 3.11Å; I427-G432 PolarHBondContact O-N 3.47Å; I427-G432 VanDerWaalsContact O-N 3.1Å
428	S	89.8	Confident	86.7	Confident	62 Å²	62	52.8 Å²	52.8	43%	0.434	28%	0.283	S	S	.	.	H	α-helix	trans	-60.4	-45	177	-163.2	0	0	0	0	112.6	L424 Y425 T426 M430 Q431	L424-S428 PolarHBondContact O-N 3.3Å; Y425-S428 WeakPolarHBondContact O-CB 3.24Å; Y425-S428 PolarHBondContact O-N 2.89Å; T426-S428 VanDerWaalsContact C-N 3.3Å; T426-S428 PolarHBondContact O-N 3.23Å; S428-M430 PolarHBondContact O-N 3.34Å; S428-Q431 PolarHBondContact O-N 2.97Å
429	C	90.6	Very high	86.4	Confident	80 Å²	80	55.7 Å²	55.7	54%	0.541	29%	0.294	S	S	.	.	H	α-helix	trans	-65.1	-31.4	177.8	-70.6	0	0	0	0	112.3	Y425 T426 I427 Q431	Y425-C429 WeakPolarHBondContact CE1-SG 3.28Å; Y425-C429 VanDerWaalsContact CZ-SG 3.52Å; Y425-C429 PolarHBondContact O-N 3.35Å; Y425-C429 PolarHBondContact O-SG 3.15Å; Y425-C429 VanDerWaalsContact O-SG 3.36Å; T426-C429 PolarHBondContact O-N 3.28Å; I427-C429 PolarHBondContact O-N 3.04Å; C429-Q431 VanDerWaalsContact C-N 3.29Å
430	M	89.2	Confident	86.1	Confident	104 Å²	104	59 Å²	59	51%	0.512	31%	0.311	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85.2	1.5	177.2	-65.9	-177.9	69.5	0	0	113.5	M118 T426 I427 S428 G432	M118-M430 HydrophobicContact CE-CB 3.89Å; M118-M430 HydrophobicContact CE-CE 4.36Å; M118-M430 HydrophobicContact CG-CE 3.87Å; M118-M430 HydrophobicContact CG-SD 4.25Å; M118-M430 HydrophobicContact SD-CB 4.11Å; T426-M430 HydrophobicContact CG2-SD 4.08Å; T426-M430 WeakPolarHBondContact O-CG 3.23Å; T426-M430 PolarHBondContact O-N 2.91Å; I427-M430 CarbonylContact O-C 3.43Å; I427-M430 PolarHBondContact O-N 3.31Å; S428-M430 PolarHBondContact O-N 3.34Å; M430-G432 PolarHBondContact O-N 3.39Å
431	Q	83.8	Confident	85.8	Confident	181 Å²	181	59.5 Å²	59.5	85%	0.846	31%	0.313	S	S	*	.	T	Hydrogen-bonded Turn	trans	56.3	31.4	-177.6	-58.1	-178.8	-32.1	0	0	113.8	I427 S428 C429	I427-Q431 PolarHBondContact O-N 2.69Å; I427-Q431 VanDerWaalsContact O-N 3.11Å; S428-Q431 PolarHBondContact O-N 2.97Å; C429-Q431 VanDerWaalsContact C-N 3.29Å
432	G	75.6	Confident	85.7	Confident	6 Å²	6	57.7 Å²	57.7	6%	0.062	30%	0.304	C	S	.	.			trans	-81	152.2	179.6	0	0	0	0	0	113.8	I427 M430	I427-G432 PolarHBondContact O-N 3.47Å; I427-G432 VanDerWaalsContact O-N 3.1Å; M430-G432 PolarHBondContact O-N 3.39Å
433	G	67.8	Low	85.6	Confident	0 Å²	0	59.3 Å²	59.3	0%	0	31%	0.309	C	S	.	.	S	Bend	trans	89	-0.1	165.7	0	0	0	0	0	116.4	D121 G348 T435	D121-G433 PolarHBondContact OD2-N 3.16Å; G348-G433 WeakPolarHBondContact CA-O 3.3Å; G433-T435 WeakPolarHBondContact O-CG2 3.29Å; G433-T435 PolarHBondContact O-N 3.34Å; G433-T435 PolarHBondContact O-OG1 3.39Å
434	H	68.6	Low	85.5	Confident	93 Å²	93	62.1 Å²	62.1	43%	0.431	32%	0.321	S	S	.	.	S	Bend	trans	54.1	8.6	-179	-59.1	-76.3	0	0	0	115.5	D121 H125 V511	D121-H434 IonicContact OD1-CD2 3.77Å; H125-H434 AromaticContact CE1-CD2 3.78Å; H125-H434 AromaticContact CE1-NE2 3.21Å; H125-H434 PolarHBondContact CE1-NE2 3.42Å; H125-H434 AromaticContact NE2-NE2 3.72Å; H434-V511 HydrophobicContact CB-CG1 3.95Å; H434-V511 HydrophobicContact CB-CG2 4.24Å
435	T	66.4	Low	85.5	Confident	33 Å²	33	62.1 Å²	62.1	20%	0.202	32%	0.321	C	S	.	.			trans	-112.2	132.5	-177	51	0	0	0	0	109.5	F352 G433 F498	F352-T435 WeakPolarHBondContact CE2-OG1 3.41Å; G433-T435 WeakPolarHBondContact O-CG2 3.29Å; G433-T435 PolarHBondContact O-N 3.34Å; G433-T435 PolarHBondContact O-OG1 3.39Å; T435-F498 HydrophobicContact CG2-CE1 4.13Å
436	T	73.2	Confident	85.7	Confident	70 Å²	70	55.2 Å²	55.2	43%	0.429	30%	0.295	S	S	.	.			trans	-72.9	137.4	168.5	79.2	0	0	0	0	109	T438 D508	T436-T438 PolarHBondContact O-N 3.06Å; T436-T438 WeakPolarHBondContact OG1-CG2 3.44Å; T436-D508 PolarHBondContact OG1-OD1 3.26Å; T436-D508 PolarHBondContact OG1-OD2 3.13Å
437	L	82.7	Confident	85.8	Confident	43 Å²	43	57.7 Å²	57.7	23%	0.225	31%	0.31	C	S	.	.			trans	-78.2	77.2	176.4	-68.5	-173.6	0	0	0	109.8	F352 L424 F441 I442	F352-L437 HydrophobicContact CE1-CD2 4.27Å; F352-L437 HydrophobicContact CZ-CD2 4.03Å; L424-L437 HydrophobicContact CB-CD1 4.17Å; L424-L437 HydrophobicContact CD2-CD2 4.36Å; L424-L437 WeakPolarHBondContact O-CD1 3.29Å; L437-F441 HydrophobicContact CD2-CD1 3.69Å; L437-F441 HydrophobicContact CD2-CE1 3.61Å; L437-I442 HydrophobicContact CB-CD1 4.35Å
438	T	86	Confident	86.1	Confident	28 Å²	28	57.8 Å²	57.8	17%	0.172	31%	0.311	C	S	.	.			trans	-66.3	154.1	171.6	70.6	0	0	0	0	110.5	T436 I440 F441 I442 D506 D508	T436-T438 PolarHBondContact O-N 3.06Å; T436-T438 WeakPolarHBondContact OG1-CG2 3.44Å; T438-I440 PolarHBondContact O-N 3.3Å; T438-F441 PolarHBondContact O-N 3.04Å; T438-F441 WeakPolarHBondContact OG1-CB 3.2Å; T438-F441 PolarHBondContact OG1-N 3.14Å; T438-I442 WeakPolarHBondContact O-CG1 3.49Å; T438-I442 PolarHBondContact O-N 3.34Å; T438-D506 PolarHBondContact OG1-OD2 3.27Å; T438-D508 WeakPolarHBondContact CG2-OD2 3.45Å
439	L	88.3	Confident	86.5	Confident	129 Å²	129	54.8 Å²	54.8	68%	0.675	29%	0.29	S	S	*	.	H	α-helix	trans	-58.5	-33.9	173.4	-177.9	63.3	0	0	0	111.4	I442 I443	L439-I442 PolarHBondContact O-N 3.3Å; L439-I443 HydrophobicContact CG-CD1 4.13Å; L439-I443 WeakPolarHBondContact O-CD1 3.05Å; L439-I443 VanDerWaalsContact O-CG1 3.25Å; L439-I443 WeakPolarHBondContact O-CG1 3.21Å; L439-I443 PolarHBondContact O-N 3.38Å
440	I	89.7	Confident	86.8	Confident	73 Å²	73	53 Å²	53	37%	0.374	28%	0.275	S	S	.	.	H	α-helix	trans	-67.3	-49	179.1	-54.1	177.6	0	0	0	109.4	T438 I442 I443 F444 L501	T438-I440 PolarHBondContact O-N 3.3Å; I440-I442 VanDerWaalsContact C-N 3.33Å; I440-I442 PolarHBondContact O-N 3.27Å; I440-I443 PolarHBondContact O-N 3.04Å; I440-I443 VanDerWaalsContact O-N 3.16Å; I440-F444 HydrophobicContact CG2-CD2 3.92Å; I440-F444 HydrophobicContact CG2-CE2 3.87Å; I440-F444 WeakPolarHBondContact O-CD2 3.41Å; I440-F444 PolarHBondContact O-N 3.04Å; I440-F444 VanDerWaalsContact O-N 3.09Å; I440-L501 HydrophobicContact CB-CD2 4.37Å; I440-L501 HydrophobicContact CG2-CD2 3.58Å
441	F	90.7	Very high	87.2	Confident	10 Å²	10	51.5 Å²	51.5	4%	0.044	27%	0.269	C	S	.	.	H	α-helix	trans	-54.3	-48.8	173.8	175.7	-95	0	0	0	111.8	F352 L424 L437 T438 I443 F444 Y445 F498 L501	F352-F441 HydrophobicContact CD1-CZ 4.3Å; F352-F441 AromaticContact CD2-CZ 3.82Å; F352-F441 HydrophobicContact CD2-CZ 3.82Å; F352-F441 AromaticContact CE1-CE1 4Å; F352-F441 HydrophobicContact CE1-CE1 4Å; F352-F441 HydrophobicContact CE1-CZ 4.03Å; F352-F441 HydrophobicContact CE2-CE1 4.12Å; F352-F441 HydrophobicContact CE2-CE2 4.29Å; F352-F441 AromaticContact CE2-CZ 3.51Å; F352-F441 HydrophobicContact CE2-CZ 3.51Å; F352-F441 HydrophobicContact CG-CZ 4.22Å; F352-F441 AromaticContact CZ-CE1 3.75Å; F352-F441 HydrophobicContact CZ-CE1 3.75Å; F352-F441 AromaticContact CZ-CZ 3.63Å; F352-F441 HydrophobicContact CZ-CZ 3.63Å; L424-F441 HydrophobicContact CD2-CE1 4.31Å; L437-F441 HydrophobicContact CD2-CD1 3.69Å; L437-F441 HydrophobicContact CD2-CE1 3.61Å; T438-F441 PolarHBondContact O-N 3.04Å; T438-F441 WeakPolarHBondContact OG1-CB 3.2Å; T438-F441 PolarHBondContact OG1-N 3.14Å; F441-I443 VanDerWaalsContact C-N 3.29Å; F441-I443 PolarHBondContact O-N 3.29Å; F441-F444 PolarHBondContact O-N 3.02Å; F441-Y445 HydrophobicContact CE1-CG 4.42Å; F441-Y445 HydrophobicContact CZ-CD2 4.2Å; F441-Y445 HydrophobicContact CZ-CG 4.49Å; F441-Y445 VanDerWaalsContact O-CB 3.29Å; F441-Y445 WeakPolarHBondContact O-CB 3.43Å; F441-Y445 PolarHBondContact O-N 3.22Å; F441-F498 HydrophobicContact CE2-CD2 4.42Å; F441-F498 HydrophobicContact CE2-CE1 4.19Å; F441-F498 AromaticContact CE2-CE2 3.67Å; F441-F498 HydrophobicContact CE2-CE2 3.67Å; F441-F498 AromaticContact CE2-CZ 3.54Å; F441-F498 HydrophobicContact CE2-CZ 3.54Å; F441-F498 HydrophobicContact CZ-CE2 4.2Å; F441-F498 HydrophobicContact CZ-CZ 4.11Å; F441-L501 HydrophobicContact CB-CD1 4.32Å; F441-L501 HydrophobicContact CD2-CD1 3.57Å; F441-L501 HydrophobicContact CE2-CD1 4.34Å; F441-L501 HydrophobicContact CG-CD1 4.39Å
442	I	92.9	Very high	87.9	Confident	43 Å²	43	42.9 Å²	42.9	22%	0.221	23%	0.229	C	C	.	.	H	α-helix	trans	-58.6	-41.4	179.7	-66.4	168.8	0	0	0	111	L421 L424 L437 T438 L439 I440 M446	L421-I442 HydrophobicContact CD2-CG2 4.12Å; L424-I442 HydrophobicContact CD1-CG1 4.37Å; L424-I442 HydrophobicContact CD1-CG2 4.46Å; L437-I442 HydrophobicContact CB-CD1 4.35Å; T438-I442 WeakPolarHBondContact O-CG1 3.49Å; T438-I442 PolarHBondContact O-N 3.34Å; L439-I442 PolarHBondContact O-N 3.3Å; I440-I442 VanDerWaalsContact C-N 3.33Å; I440-I442 PolarHBondContact O-N 3.27Å; I442-M446 WeakPolarHBondContact O-CB 3.29Å; I442-M446 PolarHBondContact O-N 3.14Å
443	I	94.2	Very high	88.9	Confident	94 Å²	94	42.7 Å²	42.7	48%	0.482	23%	0.226	S	C	.	.	H	α-helix	trans	-64.1	-47.1	178.7	-70.3	164.5	0	0	0	111.3	L439 I440 F441 T447	L439-I443 HydrophobicContact CG-CD1 4.13Å; L439-I443 WeakPolarHBondContact O-CD1 3.05Å; L439-I443 VanDerWaalsContact O-CG1 3.25Å; L439-I443 WeakPolarHBondContact O-CG1 3.21Å; L439-I443 PolarHBondContact O-N 3.38Å; I440-I443 PolarHBondContact O-N 3.04Å; I440-I443 VanDerWaalsContact O-N 3.16Å; F441-I443 VanDerWaalsContact C-N 3.29Å; F441-I443 PolarHBondContact O-N 3.29Å; I443-T447 WeakPolarHBondContact O-CB 3.26Å; I443-T447 PolarHBondContact O-N 3.41Å; I443-T447 PolarHBondContact O-OG1 3.49Å
444	F	93.5	Very high	90.2	Very high	59 Å²	59	45.9 Å²	45.9	26%	0.259	24%	0.243	S	C	.	.	H	α-helix	trans	-67.4	-46.5	179.6	-83.9	-81.6	0	0	0	112	I440 F441 M446 T447 A448 V500 L501 I504	I440-F444 HydrophobicContact CG2-CD2 3.92Å; I440-F444 HydrophobicContact CG2-CE2 3.87Å; I440-F444 WeakPolarHBondContact O-CD2 3.41Å; I440-F444 PolarHBondContact O-N 3.04Å; I440-F444 VanDerWaalsContact O-N 3.09Å; F441-F444 PolarHBondContact O-N 3.02Å; F444-M446 VanDerWaalsContact C-N 3.34Å; F444-M446 PolarHBondContact O-N 3.16Å; F444-T447 WeakPolarHBondContact O-CB 3.27Å; F444-T447 PolarHBondContact O-N 2.83Å; F444-T447 VanDerWaalsContact O-N 3.17Å; F444-A448 PolarHBondContact O-N 2.78Å; F444-V500 HydrophobicContact CD1-CG1 4.32Å; F444-V500 HydrophobicContact CE1-CB 4.26Å; F444-V500 HydrophobicContact CE1-CG1 3.5Å; F444-V500 VanDerWaalsContact CE1-CG1 3.5Å; F444-V500 HydrophobicContact CZ-CG1 3.7Å; F444-L501 HydrophobicContact CB-CD1 4.29Å; F444-L501 HydrophobicContact CB-CD2 4.43Å; F444-L501 HydrophobicContact CB-CG 4.33Å; F444-L501 HydrophobicContact CD2-CD2 3.55Å; F444-L501 HydrophobicContact CD2-CG 4.09Å; F444-L501 HydrophobicContact CE2-CD2 4.09Å; F444-L501 HydrophobicContact CG-CD2 4.19Å; F444-L501 HydrophobicContact CG-CG 4.26Å; F444-I504 HydrophobicContact CE2-CD1 3.83Å; F444-I504 HydrophobicContact CZ-CD1 3.6Å
445	Y	94.6	Very high	91.5	Very high	2 Å²	2	44 Å²	44	1%	0.008	24%	0.235	C	C	.	.	H	α-helix	trans	-57.2	-46.9	174.9	176.4	-87.6	0	0	0	111.6	F352 I356 H420 L424 F441 T447 A448 A449 L494	F352-Y445 HydrophobicContact CB-CE2 4.01Å; F352-Y445 HydrophobicContact CD1-CE2 4.09Å; F352-Y445 HydrophobicContact CG-CE2 4.28Å; I356-Y445 HydrophobicContact CD1-CE2 4.47Å; H420-Y445 HydrophobicContact CB-CE1 4.04Å; H420-Y445 PolarHBondContact CE1-OH 3.5Å; H420-Y445 AromaticContact CG-CE1 3.96Å; H420-Y445 AromaticContact ND1-CE1 3.41Å; H420-Y445 WeakPolarHBondContact ND1-CE1 3.37Å; H420-Y445 AromaticContact ND1-CZ 3.56Å; H420-Y445 PolarHBondContact ND1-OH 2.99Å; L424-Y445 HydrophobicContact CD1-CD1 3.62Å; L424-Y445 HydrophobicContact CD1-CE1 3.83Å; L424-Y445 HydrophobicContact CD1-CG 4.4Å; L424-Y445 HydrophobicContact CD2-CD1 4Å; L424-Y445 HydrophobicContact CD2-CD2 4.5Å; L424-Y445 HydrophobicContact CD2-CE1 3.78Å; L424-Y445 HydrophobicContact CD2-CE2 4.34Å; L424-Y445 HydrophobicContact CD2-CG 4.34Å; L424-Y445 HydrophobicContact CG-CD1 4.12Å; L424-Y445 HydrophobicContact CG-CE1 3.86Å; F441-Y445 HydrophobicContact CE1-CG 4.42Å; F441-Y445 HydrophobicContact CZ-CD2 4.2Å; F441-Y445 HydrophobicContact CZ-CG 4.49Å; F441-Y445 VanDerWaalsContact O-CB 3.29Å; F441-Y445 WeakPolarHBondContact O-CB 3.43Å; F441-Y445 PolarHBondContact O-N 3.22Å; Y445-T447 VanDerWaalsContact C-N 3.29Å; Y445-T447 PolarHBondContact O-N 3.18Å; Y445-A448 PolarHBondContact O-N 2.82Å; Y445-A449 PolarHBondContact O-N 2.8Å; Y445-L494 HydrophobicContact CD2-CD1 3.66Å; Y445-L494 HydrophobicContact CE2-CD1 4.02Å
446	M	96.1	Very high	92.9	Very high	19 Å²	19	42.4 Å²	42.4	9%	0.094	23%	0.226	C	C	.	.	H	α-helix	trans	-64.6	-36.6	179	-167.4	62.2	65.2	0	0	111.6	V417 H420 L421 I442 F444 A449 L450	V417-M446 HydrophobicContact CB-SD 4.24Å; V417-M446 HydrophobicContact CG1-CE 4.34Å; V417-M446 HydrophobicContact CG1-SD 4.25Å; V417-M446 HydrophobicContact CG2-SD 4.08Å; H420-M446 HydrophobicContact CB-CE 3.84Å; H420-M446 HydrophobicContact CB-SD 4.18Å; L421-M446 HydrophobicContact CD2-CE 3.83Å; L421-M446 HydrophobicContact CG-CE 3.76Å; I442-M446 WeakPolarHBondContact O-CB 3.29Å; I442-M446 PolarHBondContact O-N 3.14Å; F444-M446 VanDerWaalsContact C-N 3.34Å; F444-M446 PolarHBondContact O-N 3.16Å; M446-A449 PolarHBondContact O-N 2.91Å; M446-L450 HydrophobicContact CG-CD1 4.01Å; M446-L450 HydrophobicContact CG-CG 4.43Å; M446-L450 VanDerWaalsContact O-CB 3.31Å; M446-L450 WeakPolarHBondContact O-CB 3.33Å; M446-L450 VanDerWaalsContact O-CG 3.24Å; M446-L450 WeakPolarHBondContact O-CG 3.26Å; M446-L450 PolarHBondContact O-N 3.43Å
447	T	96.7	Very high	94	Very high	81 Å²	81	39.1 Å²	39.1	50%	0.497	21%	0.205	S	C	.	.	H	α-helix	trans	-64.3	-43.4	175	-58	0	0	0	0	111.2	I443 F444 Y445 L451	I443-T447 WeakPolarHBondContact O-CB 3.26Å; I443-T447 PolarHBondContact O-N 3.41Å; I443-T447 PolarHBondContact O-OG1 3.49Å; F444-T447 WeakPolarHBondContact O-CB 3.27Å; F444-T447 PolarHBondContact O-N 2.83Å; F444-T447 VanDerWaalsContact O-N 3.17Å; Y445-T447 VanDerWaalsContact C-N 3.29Å; Y445-T447 PolarHBondContact O-N 3.18Å; T447-L451 WeakPolarHBondContact O-CB 3.31Å; T447-L451 PolarHBondContact O-N 2.93Å
448	A	97.3	Very high	94.5	Very high	3 Å²	3	40.1 Å²	40.1	3%	0.025	21%	0.207	C	C	.	.	H	α-helix	trans	-61.8	-47.9	175.3	0	0	0	0	0	112.1	I356 F444 Y445 L451 Q452 L493 S497	I356-A448 HydrophobicContact CD1-CB 4.1Å; F444-A448 PolarHBondContact O-N 2.78Å; Y445-A448 PolarHBondContact O-N 2.82Å; A448-L451 PolarHBondContact O-N 3.04Å; A448-Q452 WeakPolarHBondContact O-CB 3.39Å; A448-Q452 PolarHBondContact O-N 3.31Å; A448-L493 HydrophobicContact CB-CB 3.89Å; A448-S497 WeakPolarHBondContact CB-OG 3.4Å
449	A	97.5	Very high	94.9	Very high	0 Å²	0	40.5 Å²	40.5	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-62.2	-44.8	178.7	0	0	0	0	0	112.1	I356 V416 Y445 M446 V453	I356-A449 HydrophobicContact CD1-CB 4.26Å; I356-A449 HydrophobicContact CG1-CB 4.42Å; V416-A449 HydrophobicContact CG1-CB 4.2Å; Y445-A449 PolarHBondContact O-N 2.8Å; M446-A449 PolarHBondContact O-N 2.91Å; A449-V453 WeakPolarHBondContact O-CG2 3.1Å; A449-V453 PolarHBondContact O-N 3.25Å
450	L	97.5	Very high	95.1	Very high	43 Å²	43	34.3 Å²	34.3	23%	0.225	18%	0.175	C	C	.	.	H	α-helix	trans	-63.5	-43.7	176	-74.2	169.3	0	0	0	111.8	F413 V416 V417 M446 L454	F413-L450 HydrophobicContact CE1-CD2 4.26Å; F413-L450 HydrophobicContact CE2-CB 4.41Å; F413-L450 HydrophobicContact CE2-CD2 3.83Å; F413-L450 HydrophobicContact CZ-CB 4.46Å; F413-L450 HydrophobicContact CZ-CD2 3.69Å; V416-L450 HydrophobicContact CB-CD2 4.06Å; V416-L450 HydrophobicContact CG1-CD2 3.89Å; V416-L450 HydrophobicContact CG1-CG 4.31Å; V417-L450 HydrophobicContact CG2-CD1 4.19Å; V417-L450 HydrophobicContact CG2-CD2 3.88Å; V417-L450 HydrophobicContact CG2-CG 4.4Å; M446-L450 HydrophobicContact CG-CD1 4.01Å; M446-L450 HydrophobicContact CG-CG 4.43Å; M446-L450 VanDerWaalsContact O-CB 3.31Å; M446-L450 WeakPolarHBondContact O-CB 3.33Å; M446-L450 VanDerWaalsContact O-CG 3.24Å; M446-L450 WeakPolarHBondContact O-CG 3.26Å; M446-L450 PolarHBondContact O-N 3.43Å; L450-L454 WeakPolarHBondContact O-CB 3.49Å; L450-L454 PolarHBondContact O-N 3.44Å
451	L	97.4	Very high	95.2	Very high	72 Å²	72	31.5 Å²	31.5	38%	0.377	16%	0.161	S	C	.	.	H	α-helix	trans	-65.6	-43.3	179.5	-177.8	59.9	0	0	0	111.6	T447 A448 L454 I455 L493	T447-L451 WeakPolarHBondContact O-CB 3.31Å; T447-L451 PolarHBondContact O-N 2.93Å; A448-L451 PolarHBondContact O-N 3.04Å; L451-L454 PolarHBondContact O-N 2.91Å; L451-I455 HydrophobicContact CD1-CD1 3.92Å; L451-I455 HydrophobicContact CD1-CG1 4.28Å; L451-I455 HydrophobicContact CG-CD1 3.94Å; L451-I455 WeakPolarHBondContact O-CD1 3.48Å; L451-I455 VanDerWaalsContact O-CG1 3.24Å; L451-I455 WeakPolarHBondContact O-CG1 3.47Å; L451-I455 PolarHBondContact O-N 2.88Å; L451-L493 HydrophobicContact CB-CD1 4.18Å; L451-L493 HydrophobicContact CD2-CD1 4.17Å; L451-L493 HydrophobicContact CD2-CD2 3.77Å; L451-L493 HydrophobicContact CG-CD1 4.05Å
452	Q	98	Very high	95.2	Very high	0 Å²	0	35.3 Å²	35.3	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-56.8	-55.8	174.6	-177.2	-154.1	0.7	0	0	110.5	I356 A448 L454 I455 L456 G486 L489 L493	I356-Q452 PolarHBondContact O-NE2 3.1Å; I356-Q452 PolarHBondContact O-OE1 2.98Å; I356-Q452 VanDerWaalsContact O-OE1 3.07Å; A448-Q452 WeakPolarHBondContact O-CB 3.39Å; A448-Q452 PolarHBondContact O-N 3.31Å; Q452-L454 VanDerWaalsContact C-N 3.34Å; Q452-L454 PolarHBondContact O-N 3.35Å; Q452-I455 PolarHBondContact O-N 2.89Å; Q452-L456 HydrophobicContact CG-CD1 3.94Å; Q452-L456 HydrophobicContact CG-CG 4.47Å; Q452-L456 WeakPolarHBondContact O-CB 3.36Å; Q452-L456 VanDerWaalsContact O-CG 3.28Å; Q452-L456 WeakPolarHBondContact O-CG 3.49Å; Q452-L456 PolarHBondContact O-N 2.78Å; Q452-G486 PolarHBondContact NE2-O 2.87Å; Q452-L489 HydrophobicContact CG-CB 4.05Å; Q452-L493 HydrophobicContact CB-CD1 3.94Å
453	V	96.8	Very high	95.1	Very high	1 Å²	1	34.1 Å²	34.1	1%	0.006	17%	0.168	C	C	.	.	H	α-helix	trans	-65.1	-37.3	-177.1	176.3	0	0	0	0	111.6	L363 F413 V416 A449 I455 L456 L457	L363-V453 HydrophobicContact CD1-CG1 4.09Å; L363-V453 HydrophobicContact CD1-CG2 4.12Å; F413-V453 HydrophobicContact CD2-CG1 4.36Å; V416-V453 HydrophobicContact CG1-CG2 4.49Å; V416-V453 HydrophobicContact CG2-CB 3.92Å; V416-V453 HydrophobicContact CG2-CG1 3.7Å; V416-V453 HydrophobicContact CG2-CG2 3.84Å; A449-V453 WeakPolarHBondContact O-CG2 3.1Å; A449-V453 PolarHBondContact O-N 3.25Å; V453-I455 PolarHBondContact O-N 2.84Å; V453-L456 PolarHBondContact O-N 3.07Å; V453-L457 HydrophobicContact CG1-CD1 3.69Å; V453-L457 HydrophobicContact CG1-CG 3.96Å; V453-L457 WeakPolarHBondContact O-CB 3.48Å; V453-L457 VanDerWaalsContact O-CG 3.26Å; V453-L457 WeakPolarHBondContact O-CG 2.93Å; V453-L457 PolarHBondContact O-N 3.32Å
454	L	96	Very high	94.9	Very high	68 Å²	68	29.6 Å²	29.6	36%	0.356	15%	0.145	S	C	.	.	H	α-helix	trans	-57.7	-49.6	174.6	-177.7	72.9	0	0	0	111.4	F399 F413 L450 L451 Q452 Y458	F399-L454 HydrophobicContact CD2-CD1 4.26Å; F399-L454 HydrophobicContact CE1-CD1 4.21Å; F399-L454 HydrophobicContact CE2-CD1 3.62Å; F399-L454 HydrophobicContact CZ-CD1 3.6Å; F399-L454 HydrophobicContact CZ-CG 4.48Å; F413-L454 HydrophobicContact CE2-CB 3.93Å; F413-L454 HydrophobicContact CE2-CD1 4.14Å; F413-L454 HydrophobicContact CZ-CD1 4.49Å; L450-L454 WeakPolarHBondContact O-CB 3.49Å; L450-L454 PolarHBondContact O-N 3.44Å; L451-L454 PolarHBondContact O-N 2.91Å; Q452-L454 VanDerWaalsContact C-N 3.34Å; Q452-L454 PolarHBondContact O-N 3.35Å; L454-Y458 WeakPolarHBondContact O-CB 3.41Å; L454-Y458 PolarHBondContact O-N 2.93Å; L454-Y458 VanDerWaalsContact O-N 3.14Å
455	I	96.3	Very high	94.6	Very high	52 Å²	52	28.4 Å²	28.4	27%	0.267	14%	0.14	S	C	.	.	H	α-helix	trans	-64	-45.3	179.3	-67.1	166.1	0	0	0	110.1	L451 Q452 V453 Y458 I459 L489	L451-I455 HydrophobicContact CD1-CD1 3.92Å; L451-I455 HydrophobicContact CD1-CG1 4.28Å; L451-I455 HydrophobicContact CG-CD1 3.94Å; L451-I455 WeakPolarHBondContact O-CD1 3.48Å; L451-I455 VanDerWaalsContact O-CG1 3.24Å; L451-I455 WeakPolarHBondContact O-CG1 3.47Å; L451-I455 PolarHBondContact O-N 2.88Å; Q452-I455 PolarHBondContact O-N 2.89Å; V453-I455 PolarHBondContact O-N 2.84Å; I455-Y458 PolarHBondContact O-N 3.45Å; I455-I459 HydrophobicContact CG2-CD1 3.57Å; I455-I459 HydrophobicContact CG2-CG1 4.33Å; I455-I459 WeakPolarHBondContact O-CB 3.35Å; I455-I459 VanDerWaalsContact O-CG1 3.3Å; I455-I459 WeakPolarHBondContact O-CG1 3.5Å; I455-I459 PolarHBondContact O-N 3.27Å; I455-L489 HydrophobicContact CB-CD1 4.11Å; I455-L489 HydrophobicContact CG2-CD1 3.55Å
456	L	96.3	Very high	94.3	Very high	1 Å²	1	33.3 Å²	33.3	1%	0.005	16%	0.159	C	C	.	.	H	α-helix	trans	-61.7	-46.8	-179.7	-74.7	177.3	0	0	0	112.8	V364 Q452 V453 Y458 I459 A460 L482 L485 L489	V364-L456 HydrophobicContact CB-CB 4Å; V364-L456 HydrophobicContact CB-CD1 4.4Å; V364-L456 HydrophobicContact CG1-CD1 4.28Å; V364-L456 HydrophobicContact CG2-CB 3.83Å; V364-L456 WeakPolarHBondContact CG2-O 3.41Å; Q452-L456 HydrophobicContact CG-CD1 3.94Å; Q452-L456 HydrophobicContact CG-CG 4.47Å; Q452-L456 WeakPolarHBondContact O-CB 3.36Å; Q452-L456 VanDerWaalsContact O-CG 3.28Å; Q452-L456 WeakPolarHBondContact O-CG 3.49Å; Q452-L456 PolarHBondContact O-N 2.78Å; V453-L456 PolarHBondContact O-N 3.07Å; L456-Y458 VanDerWaalsContact C-N 3.33Å; L456-Y458 PolarHBondContact O-N 2.99Å; L456-I459 PolarHBondContact O-N 2.94Å; L456-A460 WeakPolarHBondContact O-CB 3.23Å; L456-A460 PolarHBondContact O-N 3.41Å; L456-L482 WeakPolarHBondContact CD2-O 3.36Å; L456-L485 HydrophobicContact CD2-CB 4.24Å; L456-L485 HydrophobicContact CD2-CD2 4.32Å; L456-L485 HydrophobicContact CD2-CG 4.16Å; L456-L489 HydrophobicContact CD2-CD1 4.34Å
457	L	95.1	Very high	93.9	Very high	0 Å²	0	32.6 Å²	32.6	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-65	-37.7	178.9	-69.4	175.9	0	0	0	111.8	Q367 F399 A409 L412 F413 V453 D461	Q367-L457 HydrophobicContact CB-CD2 3.68Å; Q367-L457 HydrophobicContact CG-CD2 3.77Å; F399-L457 HydrophobicContact CE1-CB 4.01Å; F399-L457 HydrophobicContact CE1-CD1 3.99Å; F399-L457 HydrophobicContact CZ-CB 3.78Å; F399-L457 HydrophobicContact CZ-CD1 4.47Å; A409-L457 WeakPolarHBondContact O-CD1 3.38Å; L412-L457 HydrophobicContact CB-CD1 4.42Å; L412-L457 HydrophobicContact CB-CD2 4.47Å; L412-L457 HydrophobicContact CD1-CD2 4.18Å; F413-L457 HydrophobicContact CB-CD1 3.98Å; V453-L457 HydrophobicContact CG1-CD1 3.69Å; V453-L457 HydrophobicContact CG1-CG 3.96Å; V453-L457 WeakPolarHBondContact O-CB 3.48Å; V453-L457 VanDerWaalsContact O-CG 3.26Å; V453-L457 WeakPolarHBondContact O-CG 2.93Å; V453-L457 PolarHBondContact O-N 3.32Å; L457-D461 PolarHBondContact O-N 3.33Å; L457-D461 VanDerWaalsContact O-N 3.16Å
458	Y	94.3	Very high	93.5	Very high	65 Å²	65	29.6 Å²	29.6	26%	0.255	14%	0.135	S	C	.	.	H	α-helix	trans	-64.1	-46.8	173.9	172.7	-107.2	0	0	0	112.2	P393 P395 L454 I455 L456 A460 D461 W462	P393-Y458 VanDerWaalsContact O-CE2 3.32Å; P393-Y458 WeakPolarHBondContact O-CE2 3.25Å; P393-Y458 PolarHBondContact O-OH 3.01Å; P395-Y458 HydrophobicContact CB-CD2 4.19Å; P395-Y458 HydrophobicContact CB-CE2 4.24Å; P395-Y458 HydrophobicContact CG-CD2 4.06Å; P395-Y458 HydrophobicContact CG-CE2 3.68Å; L454-Y458 WeakPolarHBondContact O-CB 3.41Å; L454-Y458 PolarHBondContact O-N 2.93Å; L454-Y458 VanDerWaalsContact O-N 3.14Å; I455-Y458 PolarHBondContact O-N 3.45Å; L456-Y458 VanDerWaalsContact C-N 3.33Å; L456-Y458 PolarHBondContact O-N 2.99Å; Y458-A460 VanDerWaalsContact C-N 3.33Å; Y458-A460 PolarHBondContact O-N 3.25Å; Y458-D461 PolarHBondContact O-N 3.02Å; Y458-W462 PolarHBondContact O-N 3.42Å
459	I	94.2	Very high	92.8	Very high	35 Å²	35	31 Å²	31	18%	0.179	15%	0.15	C	C	.	.	H	α-helix	trans	-67.6	-35.8	179.1	-67.6	173.2	0	0	0	110.7	I455 L456 W462 M463 L482 L485	I455-I459 HydrophobicContact CG2-CD1 3.57Å; I455-I459 HydrophobicContact CG2-CG1 4.33Å; I455-I459 WeakPolarHBondContact O-CB 3.35Å; I455-I459 VanDerWaalsContact O-CG1 3.3Å; I455-I459 WeakPolarHBondContact O-CG1 3.5Å; I455-I459 PolarHBondContact O-N 3.27Å; L456-I459 PolarHBondContact O-N 2.94Å; I459-W462 HydrophobicContact CG2-CE3 4.36Å; I459-W462 PolarHBondContact O-N 2.99Å; I459-M463 HydrophobicContact CG2-CB 4.43Å; I459-M463 WeakPolarHBondContact O-CA 3.18Å; I459-M463 WeakPolarHBondContact O-CB 3.34Å; I459-M463 PolarHBondContact O-N 3.44Å; I459-L482 HydrophobicContact CB-CD2 4.28Å; I459-L482 HydrophobicContact CG2-CD2 3.83Å; I459-L485 HydrophobicContact CD1-CD2 3.39Å; I459-L485 HydrophobicContact CG2-CD2 4.13Å
460	A	92.7	Very high	92.3	Very high	0 Å²	0	39.1 Å²	39.1	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-59.3	-48.1	174.8	0	0	0	0	0	111.7	V364 Q367 L456 Y458 V464 L482	V364-A460 HydrophobicContact CG2-CB 3.67Å; Q367-A460 HydrophobicContact CG-CB 4.5Å; L456-A460 WeakPolarHBondContact O-CB 3.23Å; L456-A460 PolarHBondContact O-N 3.41Å; Y458-A460 VanDerWaalsContact C-N 3.33Å; Y458-A460 PolarHBondContact O-N 3.25Å; A460-V464 VanDerWaalsContact O-CB 3.3Å; A460-V464 WeakPolarHBondContact O-CB 3.21Å; A460-V464 WeakPolarHBondContact O-CG2 3.41Å; A460-V464 PolarHBondContact O-N 3.25Å; A460-L482 HydrophobicContact CB-CD1 3.75Å; A460-L482 HydrophobicContact CB-CD2 3.96Å
461	D	91.2	Very high	91.5	Very high	14 Å²	14	39 Å²	39	8%	0.075	19%	0.19	C	C	.	.	H	α-helix	trans	-59.8	-50.3	176.8	-174.8	47.5	0	0	0	111.7	I371 P393 T398 L457 Y458 H465	I371-D461 HydrophobicContact CD1-CB 4.32Å; P393-D461 VanDerWaalsContact CG-OD2 3.24Å; P393-D461 WeakPolarHBondContact CG-OD2 3.07Å; T398-D461 WeakPolarHBondContact CB-OD2 3.28Å; T398-D461 HydrophobicContact CG2-CB 3.48Å; T398-D461 VanDerWaalsContact CG2-CB 3.48Å; T398-D461 WeakPolarHBondContact CG2-OD2 2.8Å; T398-D461 PolarHBondContact OG1-OD2 2.96Å; L457-D461 PolarHBondContact O-N 3.33Å; L457-D461 VanDerWaalsContact O-N 3.16Å; Y458-D461 PolarHBondContact O-N 3.02Å; D461-H465 PolarHBondContact O-N 2.62Å; D461-H465 PolarHBondContact O-ND1 3.45Å; D461-H465 IonicContact OD1-CE1 2.66Å; D461-H465 PolarHBondContact OD1-CE1 3.24Å; D461-H465 IonicContact OD1-ND1 3.65Å; D461-H465 PolarHBondContact OD1-ND1 3.43Å
462	W	91	Very high	90.8	Very high	90 Å²	90	38.7 Å²	38.7	34%	0.341	19%	0.188	S	C	.	.	H	α-helix	trans	-62.1	-49.5	178.2	169.3	63.7	0	0	0	112.9	C392 P393 Y458 I459 W466	C392-W462 PolarHBondContact SG-NE1 3.47Å; P393-W462 HydrophobicContact CG-CB 4.35Å; Y458-W462 PolarHBondContact O-N 3.42Å; I459-W462 HydrophobicContact CG2-CE3 4.36Å; I459-W462 PolarHBondContact O-N 2.99Å; W462-W466 VanDerWaalsContact O-CB 3.22Å; W462-W466 WeakPolarHBondContact O-CB 3.41Å; W462-W466 PolarHBondContact O-N 3.02Å
463	M	91.2	Very high	90	Very high	17 Å²	17	41 Å²	41	8%	0.084	20%	0.2	C	C	.	.	H	α-helix	trans	-71.8	-40.3	-170	-170.7	-178.9	66.8	0	0	111.9	I459 W466 M467 S478 Y481 L482	I459-M463 HydrophobicContact CG2-CB 4.43Å; I459-M463 WeakPolarHBondContact O-CA 3.18Å; I459-M463 WeakPolarHBondContact O-CB 3.34Å; I459-M463 PolarHBondContact O-N 3.44Å; M463-W466 PolarHBondContact O-N 3.47Å; M463-M467 HydrophobicContact CE-CE 4.11Å; M463-M467 HydrophobicContact CG-CE 3.76Å; M463-M467 HydrophobicContact CG-CG 4.41Å; M463-M467 HydrophobicContact CG-SD 4.14Å; M463-M467 WeakPolarHBondContact O-CB 3.25Å; M463-M467 VanDerWaalsContact O-CG 3.26Å; M463-M467 WeakPolarHBondContact O-CG 3.3Å; M463-M467 PolarHBondContact O-N 3.07Å; M463-M467 HydrophobicContact SD-CE 3.78Å; M463-S478 VanDerWaalsContact CE-CA 3.43Å; M463-S478 WeakPolarHBondContact CE-O 3.5Å; M463-Y481 HydrophobicContact SD-CD2 4.07Å; M463-Y481 HydrophobicContact SD-CG 4.5Å; M463-L482 HydrophobicContact CE-CD1 3.64Å; M463-L482 HydrophobicContact CE-CD2 3.84Å; M463-L482 HydrophobicContact CE-CG 3.41Å; M463-L482 VanDerWaalsContact CE-CG 3.41Å
464	V	89.3	Confident	89.3	Confident	0 Å²	0	40.9 Å²	40.9	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-63.1	-46.5	177.4	172.1	0	0	0	0	110.5	A368 I371 L375 A460 W466 M467 W468 P474	A368-V464 HydrophobicContact CB-CG2 4.16Å; I371-V464 HydrophobicContact CB-CB 4.49Å; I371-V464 HydrophobicContact CB-CG1 4Å; I371-V464 HydrophobicContact CG2-CB 4Å; I371-V464 HydrophobicContact CG2-CG1 3.45Å; I371-V464 VanDerWaalsContact CG2-CG1 3.45Å; L375-V464 HydrophobicContact CD1-CG1 3.72Å; A460-V464 VanDerWaalsContact O-CB 3.3Å; A460-V464 WeakPolarHBondContact O-CB 3.21Å; A460-V464 WeakPolarHBondContact O-CG2 3.41Å; A460-V464 PolarHBondContact O-N 3.25Å; V464-W466 VanDerWaalsContact C-N 3.33Å; V464-W466 PolarHBondContact O-N 2.92Å; V464-M467 PolarHBondContact O-N 3.33Å; V464-W468 VanDerWaalsContact O-CB 3.3Å; V464-W468 WeakPolarHBondContact O-CB 3.4Å; V464-W468 PolarHBondContact O-N 3.48Å; V464-P474 HydrophobicContact CB-CB 4.39Å; V464-P474 HydrophobicContact CG1-CB 3.81Å; V464-P474 HydrophobicContact CG1-CG 3.99Å; V464-P474 HydrophobicContact CG2-CB 4.34Å
465	H	87.6	Confident	88.2	Confident	33 Å²	33	40 Å²	40	15%	0.153	20%	0.195	C	C	.	.	H	α-helix	trans	-65.5	-36.1	175.7	-70.8	98.5	0	0	0	112.6	D461 G469	D461-H465 PolarHBondContact O-N 2.62Å; D461-H465 PolarHBondContact O-ND1 3.45Å; D461-H465 IonicContact OD1-CE1 2.66Å; D461-H465 PolarHBondContact OD1-CE1 3.24Å; D461-H465 IonicContact OD1-ND1 3.65Å; D461-H465 PolarHBondContact OD1-ND1 3.43Å; H465-G469 PolarHBondContact O-N 2.82Å
466	W	87.6	Confident	87.3	Confident	106 Å²	106	40.3 Å²	40.3	40%	0.402	20%	0.198	S	C	.	.	H	α-helix	trans	-65.7	-44.8	176.5	177.4	84.7	0	0	0	112.1	W462 M463 V464 G469 R470	W462-W466 VanDerWaalsContact O-CB 3.22Å; W462-W466 WeakPolarHBondContact O-CB 3.41Å; W462-W466 PolarHBondContact O-N 3.02Å; M463-W466 PolarHBondContact O-N 3.47Å; V464-W466 VanDerWaalsContact C-N 3.33Å; V464-W466 PolarHBondContact O-N 2.92Å; W466-G469 PolarHBondContact O-N 3.49Å; W466-R470 HydrophobicContact CZ2-CG 4.43Å; W466-R470 WeakPolarHBondContact O-CG 3.42Å; W466-R470 PolarHBondContact O-N 3.22Å
467	M	88.5	Confident	86.7	Confident	4 Å²	4	42 Å²	42	2%	0.02	21%	0.205	C	C	.	.	H	α-helix	trans	-61.9	-46.6	174.6	-73.6	175.2	169.8	0	0	111.1	M463 V464 G469 R470 G471 L472 P474 F477 Y481	M463-M467 HydrophobicContact CE-CE 4.11Å; M463-M467 HydrophobicContact CG-CE 3.76Å; M463-M467 HydrophobicContact CG-CG 4.41Å; M463-M467 HydrophobicContact CG-SD 4.14Å; M463-M467 WeakPolarHBondContact O-CB 3.25Å; M463-M467 VanDerWaalsContact O-CG 3.26Å; M463-M467 WeakPolarHBondContact O-CG 3.3Å; M463-M467 PolarHBondContact O-N 3.07Å; M463-M467 HydrophobicContact SD-CE 3.78Å; V464-M467 PolarHBondContact O-N 3.33Å; M467-G469 VanDerWaalsContact C-N 3.32Å; M467-G469 PolarHBondContact O-N 3.02Å; M467-R470 CarbonylContact O-C 3.55Å; M467-R470 WeakPolarHBondContact O-CA 3.41Å; M467-R470 WeakPolarHBondContact O-CB 3.46Å; M467-R470 PolarHBondContact O-N 2.9Å; M467-G471 PolarHBondContact O-N 3.27Å; M467-L472 CarbonylContact C-O 3.6Å; M467-L472 HydrophobicContact CB-CB 4.19Å; M467-L472 PolarHBondContact O-N 3.22Å; M467-P474 HydrophobicContact CB-CB 4.42Å; M467-P474 HydrophobicContact SD-CB 4.46Å; M467-F477 HydrophobicContact CE-CB 3.53Å; M467-F477 HydrophobicContact SD-CB 3.77Å; M467-Y481 HydrophobicContact CE-CD2 3.56Å; M467-Y481 HydrophobicContact CE-CE2 3.65Å
468	W	86.7	Confident	86.3	Confident	18 Å²	18	42 Å²	42	7%	0.068	21%	0.205	C	C	.	.	H	α-helix	trans	-56.5	-45.1	176.3	-172.9	-93.7	0	0	0	112.5	L375 H376 G379 M380 P381 G382 V464 R470 G471 P474	L375-W468 HydrophobicContact CB-CD2 3.66Å; L375-W468 HydrophobicContact CB-CE3 3.59Å; L375-W468 HydrophobicContact CB-CG 4.37Å; L375-W468 HydrophobicContact CB-CH2 3.86Å; L375-W468 HydrophobicContact CB-CZ2 3.9Å; L375-W468 HydrophobicContact CB-CZ3 3.68Å; L375-W468 HydrophobicContact CD1-CB 3.86Å; L375-W468 HydrophobicContact CD1-CD2 3.88Å; L375-W468 HydrophobicContact CD1-CE3 4.02Å; L375-W468 HydrophobicContact CD1-CG 3.8Å; L375-W468 HydrophobicContact CD2-CD2 4.48Å; L375-W468 HydrophobicContact CD2-CG 4.41Å; L375-W468 HydrophobicContact CG-CD2 4.22Å; L375-W468 HydrophobicContact CG-CE3 4.41Å; L375-W468 HydrophobicContact CG-CG 4.43Å; L375-W468 WeakPolarHBondContact O-CH2 3.45Å; L375-W468 WeakPolarHBondContact O-CZ2 3.21Å; H376-W468 HydrophobicContact CB-CH2 4.4Å; H376-W468 AromaticContact CD2-CZ3 3.9Å; H376-W468 AromaticContact CE1-CZ3 3.77Å; H376-W468 AromaticContact CG-CH2 3.95Å; H376-W468 AromaticContact CG-CZ3 3.79Å; H376-W468 AromaticContact ND1-CH2 3.73Å; H376-W468 AromaticContact ND1-CZ3 3.71Å; H376-W468 AromaticContact NE2-CZ3 3.88Å; G379-W468 WeakPolarHBondContact O-CH2 3.48Å; G379-W468 VanDerWaalsContact O-CZ2 3.24Å; G379-W468 WeakPolarHBondContact O-CZ2 3.27Å; M380-W468 WeakPolarHBondContact O-CZ2 3.43Å; P381-W468 HydrophobicContact CB-CD2 4.48Å; P381-W468 HydrophobicContact CB-CE3 4.28Å; P381-W468 HydrophobicContact CB-CZ3 4.31Å; P381-W468 VanDerWaalsContact CD-CH2 3.5Å; P381-W468 HydrophobicContact CG-CE3 4Å; P381-W468 HydrophobicContact CG-CH2 3.82Å; P381-W468 HydrophobicContact CG-CZ2 4.46Å; P381-W468 HydrophobicContact CG-CZ3 3.59Å; G382-W468 PolarHBondContact N-O 3.35Å; V464-W468 VanDerWaalsContact O-CB 3.3Å; V464-W468 WeakPolarHBondContact O-CB 3.4Å; V464-W468 PolarHBondContact O-N 3.48Å; W468-R470 PolarHBondContact O-N 3.25Å; W468-G471 PolarHBondContact O-N 2.85Å; W468-G471 VanDerWaalsContact O-N 3.1Å; W468-P474 HydrophobicContact CE3-CG 4.11Å
469	G	83.9	Confident	86	Confident	32 Å²	32	39.6 Å²	39.6	33%	0.33	20%	0.196	S	C	.	.	H	α-helix	trans	-66.4	-18.3	176.7	0	0	0	0	0	114.3	H465 W466 M467	H465-G469 PolarHBondContact O-N 2.82Å; W466-G469 PolarHBondContact O-N 3.49Å; M467-G469 VanDerWaalsContact C-N 3.32Å; M467-G469 PolarHBondContact O-N 3.02Å
470	R	85.7	Confident	85.8	Confident	170 Å²	170	38.1 Å²	38.1	64%	0.642	19%	0.189	S	C	*	.	T	Hydrogen-bonded Turn	trans	-93.2	-0.5	174.7	-71	-73.9	-175.9	100.4	-2	113.3	W466 M467 W468 L472	W466-R470 HydrophobicContact CZ2-CG 4.43Å; W466-R470 WeakPolarHBondContact O-CG 3.42Å; W466-R470 PolarHBondContact O-N 3.22Å; M467-R470 CarbonylContact O-C 3.55Å; M467-R470 WeakPolarHBondContact O-CA 3.41Å; M467-R470 WeakPolarHBondContact O-CB 3.46Å; M467-R470 PolarHBondContact O-N 2.9Å; W468-R470 PolarHBondContact O-N 3.25Å; R470-L472 HydrophobicContact CB-CD1 4.39Å; R470-L472 HydrophobicContact CB-CG 4.23Å; R470-L472 PolarHBondContact O-N 3.42Å
471	G	82	Confident	85.8	Confident	41 Å²	41	40.1 Å²	40.1	42%	0.423	20%	0.197	S	C	.	.	T	Hydrogen-bonded Turn	trans	71.6	17	-174	0	0	0	0	0	113.4	M467 W468	M467-G471 PolarHBondContact O-N 3.27Å; W468-G471 PolarHBondContact O-N 2.85Å; W468-G471 VanDerWaalsContact O-N 3.1Å
472	L	82.4	Confident	85.9	Confident	66 Å²	66	39.4 Å²	39.4	35%	0.346	19%	0.193	S	C	.	.			trans	-88.4	133.4	170.7	-61.7	175.6	0	0	0	108.2	M467 R470 P474 F477	M467-L472 CarbonylContact C-O 3.6Å; M467-L472 HydrophobicContact CB-CB 4.19Å; M467-L472 PolarHBondContact O-N 3.22Å; R470-L472 HydrophobicContact CB-CD1 4.39Å; R470-L472 HydrophobicContact CB-CG 4.23Å; R470-L472 PolarHBondContact O-N 3.42Å; L472-P474 WeakPolarHBondContact O-CD 3.16Å; L472-F477 HydrophobicContact CB-CD2 4.38Å; L472-F477 HydrophobicContact CB-CE2 4.41Å; L472-F477 HydrophobicContact CD2-CE2 4.38Å; L472-F477 HydrophobicContact CD2-CZ 4.48Å
473	D	80.4	Confident	86	Confident	47 Å²	47	35.4 Å²	35.4	25%	0.251	18%	0.178	S	C	.	.			trans	-73.3	107.6	175.2	-179.2	7.5	0	0	0	110	H376 D475 N476 F477	H376-D473 IonicContact CE1-OD1 3.74Å; H376-D473 IonicContact NE2-OD1 3.95Å; H376-D473 PolarHBondContact NE2-OD1 2.69Å; D473-D475 PolarHBondContact O-N 3.3Å; D473-D475 VanDerWaalsContact O-N 3.08Å; D473-D475 PolarHBondContact OD1-N 2.9Å; D473-N476 PolarHBondContact O-N 3.29Å; D473-N476 VanDerWaalsContact O-N 3.1Å; D473-N476 PolarHBondContact OD2-ND2 2.99Å; D473-F477 VanDerWaalsContact O-CD2 3.31Å; D473-F477 WeakPolarHBondContact O-CD2 3.19Å
474	P	82.1	Confident	86.1	Confident	0 Å²	0	34.6 Å²	34.6	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-57.5	-27.1	-174.9	22.5	-32.2	0	0	0	113.1	S372 V464 M467 W468 L472 N476 F477 S478	S372-P474 WeakPolarHBondContact OG-CG 3.46Å; V464-P474 HydrophobicContact CB-CB 4.39Å; V464-P474 HydrophobicContact CG1-CB 3.81Å; V464-P474 HydrophobicContact CG1-CG 3.99Å; V464-P474 HydrophobicContact CG2-CB 4.34Å; M467-P474 HydrophobicContact CB-CB 4.42Å; M467-P474 HydrophobicContact SD-CB 4.46Å; W468-P474 HydrophobicContact CE3-CG 4.11Å; L472-P474 WeakPolarHBondContact O-CD 3.16Å; P474-N476 PolarHBondContact O-N 3.43Å; P474-N476 VanDerWaalsContact O-N 3.15Å; P474-F477 PolarHBondContact O-N 3.38Å; P474-F477 VanDerWaalsContact O-N 3.13Å; P474-S478 WeakPolarHBondContact O-CB 3.26Å; P474-S478 PolarHBondContact O-N 2.84Å; P474-S478 PolarHBondContact O-OG 2.92Å
475	D	74.2	Confident	86.4	Confident	48 Å²	48	36.5 Å²	36.5	26%	0.257	19%	0.185	S	C	.	.	H	α-helix	trans	-59.8	-28.7	179	-74	-19.4	0	0	0	113.5	S372 H376 D473	S372-D475 WeakPolarHBondContact CB-OD1 3.45Å; S372-D475 PolarHBondContact OG-OD1 3.33Å; S372-D475 PolarHBondContact OG-OD2 3.33Å; H376-D475 IonicContact CD2-OD2 3.67Å; H376-D475 IonicContact NE2-OD2 2.63Å; D473-D475 PolarHBondContact O-N 3.3Å; D473-D475 VanDerWaalsContact O-N 3.08Å; D473-D475 PolarHBondContact OD1-N 2.9Å
476	N	76	Confident	86.8	Confident	60 Å²	60	35 Å²	35	32%	0.321	18%	0.177	S	C	.	.	H	α-helix	trans	-87.9	-20.9	-179.6	-69.2	-55.6	0	0	0	113.6	R156 P322 D473 P474	R156-N476 PolarHBondContact NH2-OD1 3.14Å; P322-N476 WeakPolarHBondContact CG-O 3.31Å; D473-N476 PolarHBondContact O-N 3.29Å; D473-N476 VanDerWaalsContact O-N 3.1Å; D473-N476 PolarHBondContact OD2-ND2 2.99Å; P474-N476 PolarHBondContact O-N 3.43Å; P474-N476 VanDerWaalsContact O-N 3.15Å
477	F	84.2	Confident	87.1	Confident	35 Å²	35	30.4 Å²	30.4	15%	0.154	16%	0.161	C	C	.	.	H	α-helix	trans	-121.3	-35.8	-168.7	-61.5	-89.2	0	0	0	113.8	P322 M467 L472 D473 P474 P480 Y481	P322-F477 HydrophobicContact CB-CD1 4.09Å; P322-F477 HydrophobicContact CG-CD1 3.88Å; P322-F477 HydrophobicContact CG-CE1 4.28Å; M467-F477 HydrophobicContact CE-CB 3.53Å; M467-F477 HydrophobicContact SD-CB 3.77Å; L472-F477 HydrophobicContact CB-CD2 4.38Å; L472-F477 HydrophobicContact CB-CE2 4.41Å; L472-F477 HydrophobicContact CD2-CE2 4.38Å; L472-F477 HydrophobicContact CD2-CZ 4.48Å; D473-F477 VanDerWaalsContact O-CD2 3.31Å; D473-F477 WeakPolarHBondContact O-CD2 3.19Å; P474-F477 PolarHBondContact O-N 3.38Å; P474-F477 VanDerWaalsContact O-N 3.13Å; F477-P480 WeakPolarHBondContact O-CD 3.43Å; F477-Y481 HydrophobicContact CB-CE2 4.11Å; F477-Y481 WeakPolarHBondContact O-CD2 3.29Å; F477-Y481 WeakPolarHBondContact O-CE2 3.27Å
478	S	87.8	Confident	87.5	Confident	0 Å²	0	32.4 Å²	32.4	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-72.1	-44.4	-166.7	68.5	0	0	0	0	112.8	M463 P474 Y481 L482	M463-S478 VanDerWaalsContact CE-CA 3.43Å; M463-S478 WeakPolarHBondContact CE-O 3.5Å; P474-S478 WeakPolarHBondContact O-CB 3.26Å; P474-S478 PolarHBondContact O-N 2.84Å; P474-S478 PolarHBondContact O-OG 2.92Å; S478-Y481 PolarHBondContact O-N 3.43Å; S478-L482 WeakPolarHBondContact O-CB 3.39Å; S478-L482 WeakPolarHBondContact O-CD1 3.36Å; S478-L482 VanDerWaalsContact O-CG 3.23Å; S478-L482 WeakPolarHBondContact O-CG 3.3Å; S478-L482 PolarHBondContact O-N 3.26Å
479	I	87.4	Confident	88.1	Confident	16 Å²	16	33.3 Å²	33.3	8%	0.082	18%	0.178	C	C	.	.	H	α-helix	trans	-59.9	-50.5	-176.7	-63.7	171.5	0	0	0	110.5	M151 A365 A368 Y481 L482 T483	M151-I479 HydrophobicContact CE-CG2 4.45Å; A365-I479 HydrophobicContact CB-CG2 4.11Å; A368-I479 HydrophobicContact CB-CG1 4.36Å; I479-Y481 VanDerWaalsContact C-N 3.34Å; I479-Y481 PolarHBondContact O-N 3.37Å; I479-L482 PolarHBondContact O-N 2.82Å; I479-T483 HydrophobicContact CG2-CG2 4.01Å; I479-T483 WeakPolarHBondContact O-CG2 3.5Å; I479-T483 PolarHBondContact O-N 3.09Å; I479-T483 PolarHBondContact O-OG1 3.42Å
480	P	90.2	Very high	88.7	Confident	4 Å²	4	31.8 Å²	31.8	3%	0.026	16%	0.162	C	C	.	.	H	α-helix	trans	-54.8	-42.1	178.1	-30.1	37.4	0	0	0	115.7	N148 P322 A326 F477 T483 A484	N148-P480 HydrophobicContact CB-CB 4.34Å; N148-P480 HydrophobicContact CB-CG 4.17Å; N148-P480 VanDerWaalsContact OD1-CA 3.28Å; N148-P480 WeakPolarHBondContact OD1-CA 3.18Å; P322-P480 HydrophobicContact CB-CB 3.97Å; P322-P480 HydrophobicContact CB-CG 4.08Å; A326-P480 HydrophobicContact CB-CB 3.86Å; A326-P480 WeakPolarHBondContact CB-O 3.33Å; F477-P480 WeakPolarHBondContact O-CD 3.43Å; P480-T483 PolarHBondContact O-OG1 3.38Å; P480-T483 VanDerWaalsContact O-OG1 3.14Å; P480-A484 WeakPolarHBondContact O-CB 3.39Å; P480-A484 PolarHBondContact O-N 3.02Å
481	Y	92.5	Very high	89.2	Confident	41 Å²	41	23.7 Å²	23.7	16%	0.161	13%	0.131	C	C	.	.	H	α-helix	trans	-72	-38.9	178.9	-61.2	-46.7	0	0	0	112.4	P322 I325 M463 M467 F477 S478 I479 L485	P322-Y481 HydrophobicContact CB-CE1 4.34Å; P322-Y481 HydrophobicContact CB-CE2 4.41Å; I325-Y481 HydrophobicContact CB-CE1 3.8Å; I325-Y481 HydrophobicContact CD1-CE1 4.26Å; I325-Y481 HydrophobicContact CG2-CD1 4.04Å; I325-Y481 HydrophobicContact CG2-CE1 3.58Å; M463-Y481 HydrophobicContact SD-CD2 4.07Å; M463-Y481 HydrophobicContact SD-CG 4.5Å; M467-Y481 HydrophobicContact CE-CD2 3.56Å; M467-Y481 HydrophobicContact CE-CE2 3.65Å; F477-Y481 HydrophobicContact CB-CE2 4.11Å; F477-Y481 WeakPolarHBondContact O-CD2 3.29Å; F477-Y481 WeakPolarHBondContact O-CE2 3.27Å; S478-Y481 PolarHBondContact O-N 3.43Å; I479-Y481 VanDerWaalsContact C-N 3.34Å; I479-Y481 PolarHBondContact O-N 3.37Å; Y481-L485 WeakPolarHBondContact O-CB 3.32Å; Y481-L485 PolarHBondContact O-N 3.41Å
482	L	93.3	Very high	89.9	Confident	0 Å²	0	22.9 Å²	22.9	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-70.5	-40.6	-177.7	-69.4	162.6	0	0	0	111.8	V364 A368 L456 I459 A460 M463 S478 I479 G486	V364-L482 HydrophobicContact CG1-CB 3.79Å; V364-L482 HydrophobicContact CG2-CB 3.88Å; V364-L482 HydrophobicContact CG2-CD1 4.02Å; V364-L482 HydrophobicContact CG2-CD2 3.9Å; V364-L482 HydrophobicContact CG2-CG 4.11Å; A368-L482 HydrophobicContact CB-CD1 3.62Å; L456-L482 WeakPolarHBondContact CD2-O 3.36Å; I459-L482 HydrophobicContact CB-CD2 4.28Å; I459-L482 HydrophobicContact CG2-CD2 3.83Å; A460-L482 HydrophobicContact CB-CD1 3.75Å; A460-L482 HydrophobicContact CB-CD2 3.96Å; M463-L482 HydrophobicContact CE-CD1 3.64Å; M463-L482 HydrophobicContact CE-CD2 3.84Å; M463-L482 HydrophobicContact CE-CG 3.41Å; M463-L482 VanDerWaalsContact CE-CG 3.41Å; S478-L482 WeakPolarHBondContact O-CB 3.39Å; S478-L482 WeakPolarHBondContact O-CD1 3.36Å; S478-L482 VanDerWaalsContact O-CG 3.23Å; S478-L482 WeakPolarHBondContact O-CG 3.3Å; S478-L482 PolarHBondContact O-N 3.26Å; I479-L482 PolarHBondContact O-N 2.82Å; L482-G486 PolarHBondContact O-N 2.85Å
483	T	92.3	Very high	90.6	Very high	5 Å²	5	21.1 Å²	21.1	3%	0.031	11%	0.113	C	C	.	.	H	α-helix	trans	-65.9	-46.2	176.3	52.8	0	0	0	0	110.9	N148 M151 I479 P480 L485 G486 D487	N148-T483 PolarHBondContact OD1-OG1 3.48Å; M151-T483 HydrophobicContact CE-CG2 3.86Å; I479-T483 HydrophobicContact CG2-CG2 4.01Å; I479-T483 WeakPolarHBondContact O-CG2 3.5Å; I479-T483 PolarHBondContact O-N 3.09Å; I479-T483 PolarHBondContact O-OG1 3.42Å; P480-T483 PolarHBondContact O-OG1 3.38Å; P480-T483 VanDerWaalsContact O-OG1 3.14Å; T483-L485 PolarHBondContact O-N 3.46Å; T483-G486 CarbonylContact O-C 3.56Å; T483-G486 VanDerWaalsContact O-CA 3.28Å; T483-G486 WeakPolarHBondContact O-CA 3.24Å; T483-G486 PolarHBondContact O-N 2.95Å; T483-D487 PolarHBondContact O-N 3.4Å
484	A	94.3	Very high	91.4	Very high	0 Å²	0	18.9 Å²	18.9	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-65	-38.6	178.2	0	0	0	0	0	113	A326 I329 S330 P480 G486 D487 L488	A326-A484 HydrophobicContact CB-CB 3.78Å; A326-A484 WeakPolarHBondContact O-CB 3.27Å; I329-A484 HydrophobicContact CB-CB 3.93Å; I329-A484 HydrophobicContact CG2-CB 3.97Å; I329-A484 WeakPolarHBondContact CG2-O 3.44Å; S330-A484 WeakPolarHBondContact OG-CA 3.41Å; S330-A484 WeakPolarHBondContact OG-CB 3.26Å; P480-A484 WeakPolarHBondContact O-CB 3.39Å; P480-A484 PolarHBondContact O-N 3.02Å; A484-G486 PolarHBondContact O-N 3.29Å; A484-D487 PolarHBondContact O-N 3.41Å; A484-L488 PolarHBondContact O-N 3.44Å; A484-L488 VanDerWaalsContact O-N 3.08Å
485	L	95.7	Very high	92	Very high	41 Å²	41	19.6 Å²	19.6	22%	0.215	11%	0.107	C	C	.	.	H	α-helix	trans	-63.8	-35.4	170.7	-175.5	62.2	0	0	0	111.1	L456 I459 Y481 T483 L488 L489	L456-L485 HydrophobicContact CD2-CB 4.24Å; L456-L485 HydrophobicContact CD2-CD2 4.32Å; L456-L485 HydrophobicContact CD2-CG 4.16Å; I459-L485 HydrophobicContact CD1-CD2 3.39Å; I459-L485 HydrophobicContact CG2-CD2 4.13Å; Y481-L485 WeakPolarHBondContact O-CB 3.32Å; Y481-L485 PolarHBondContact O-N 3.41Å; T483-L485 PolarHBondContact O-N 3.46Å; L485-L488 PolarHBondContact O-N 2.89Å; L485-L489 HydrophobicContact CD1-CD1 4.04Å; L485-L489 HydrophobicContact CD1-CG 3.96Å; L485-L489 HydrophobicContact CD2-CD1 4.28Å; L485-L489 HydrophobicContact CG-CD1 3.76Å; L485-L489 HydrophobicContact CG-CG 4.11Å; L485-L489 VanDerWaalsContact O-CB 3.28Å; L485-L489 WeakPolarHBondContact O-CB 3.35Å; L485-L489 VanDerWaalsContact O-CG 3.25Å; L485-L489 WeakPolarHBondContact O-CG 3.43Å; L485-L489 PolarHBondContact O-N 2.98Å
486	G	95.4	Very high	92.9	Very high	0 Å²	0	22.1 Å²	22.1	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-62.8	-41.9	174.5	0	0	0	0	0	112.8	Q452 L482 T483 A484 G490	Q452-G486 PolarHBondContact NE2-O 2.87Å; L482-G486 PolarHBondContact O-N 2.85Å; T483-G486 CarbonylContact O-C 3.56Å; T483-G486 VanDerWaalsContact O-CA 3.28Å; T483-G486 WeakPolarHBondContact O-CA 3.24Å; T483-G486 PolarHBondContact O-N 2.95Å; A484-G486 PolarHBondContact O-N 3.29Å; G486-G490 WeakPolarHBondContact O-CA 3.28Å; G486-G490 PolarHBondContact O-N 2.86Å
487	D	94.9	Very high	93.7	Very high	11 Å²	11	19.8 Å²	19.8	6%	0.059	11%	0.109	C	C	.	.	H	α-helix	trans	-62.7	-47.1	174.9	-63.6	-24.9	0	0	0	111.5	S330 N357 T483 A484 T491	S330-D487 PolarHBondContact OG-OD2 3.41Å; N357-D487 PolarHBondContact OD1-O 3.3Å; T483-D487 PolarHBondContact O-N 3.4Å; A484-D487 PolarHBondContact O-N 3.41Å; D487-T491 VanDerWaalsContact O-CB 3.29Å; D487-T491 WeakPolarHBondContact O-CB 3.3Å; D487-T491 PolarHBondContact O-N 3.45Å; D487-T491 PolarHBondContact O-OG1 2.95Å
488	L	96.8	Very high	94	Very high	45 Å²	45	18.8 Å²	18.8	24%	0.236	10%	0.104	C	C	.	.	H	α-helix	trans	-65.9	-49.4	-179.8	176.6	60.9	0	0	0	111.8	I329 V332 I336 A484 L485 G492	I329-L488 HydrophobicContact CG2-CB 4.11Å; I329-L488 HydrophobicContact CG2-CD2 4.04Å; V332-L488 HydrophobicContact CB-CD1 4.14Å; V332-L488 HydrophobicContact CG1-CD1 3.76Å; I336-L488 HydrophobicContact CD1-CD1 3.86Å; A484-L488 PolarHBondContact O-N 3.44Å; A484-L488 VanDerWaalsContact O-N 3.08Å; L485-L488 PolarHBondContact O-N 2.89Å; L488-G492 PolarHBondContact O-N 3.23Å
489	L	97.6	Very high	94.2	Very high	38 Å²	38	22.9 Å²	22.9	20%	0.199	12%	0.123	C	C	.	.	H	α-helix	trans	-66.6	-43.1	179.7	-70.3	177.3	0	0	0	111.5	Q452 I455 L456 L485 G492 L493	Q452-L489 HydrophobicContact CG-CB 4.05Å; I455-L489 HydrophobicContact CB-CD1 4.11Å; I455-L489 HydrophobicContact CG2-CD1 3.55Å; L456-L489 HydrophobicContact CD2-CD1 4.34Å; L485-L489 HydrophobicContact CD1-CD1 4.04Å; L485-L489 HydrophobicContact CD1-CG 3.96Å; L485-L489 HydrophobicContact CD2-CD1 4.28Å; L485-L489 HydrophobicContact CG-CD1 3.76Å; L485-L489 HydrophobicContact CG-CG 4.11Å; L485-L489 VanDerWaalsContact O-CB 3.28Å; L485-L489 WeakPolarHBondContact O-CB 3.35Å; L485-L489 VanDerWaalsContact O-CG 3.25Å; L485-L489 WeakPolarHBondContact O-CG 3.43Å; L485-L489 PolarHBondContact O-N 2.98Å; L489-G492 PolarHBondContact O-N 2.95Å; L489-L493 WeakPolarHBondContact O-CB 3.4Å; L489-L493 WeakPolarHBondContact O-CG 3.47Å; L489-L493 PolarHBondContact O-N 3.25Å
490	G	97.1	Very high	94.4	Very high	0 Å²	0	24.1 Å²	24.1	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-62.2	-51.4	179.8	0	0	0	0	0	111.3	N357 G486 L494	N357-G490 VanDerWaalsContact OD1-CA 3.28Å; N357-G490 WeakPolarHBondContact OD1-CA 3.27Å; G486-G490 WeakPolarHBondContact O-CA 3.28Å; G486-G490 PolarHBondContact O-N 2.86Å; G490-L494 WeakPolarHBondContact O-CB 3.41Å; G490-L494 PolarHBondContact O-N 3.39Å
491	T	96.5	Very high	94.3	Very high	0 Å²	0	24.4 Å²	24.4	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-62.9	-44.8	177.4	-45.6	0	0	0	0	111.7	G333 I336 L337 T353 N357 D487 A495	G333-T491 WeakPolarHBondContact O-CG2 3.27Å; I336-T491 HydrophobicContact CB-CG2 4.06Å; I336-T491 HydrophobicContact CG2-CG2 3.99Å; L337-T491 HydrophobicContact CB-CG2 4.01Å; T353-T491 HydrophobicContact CG2-CG2 4.19Å; N357-T491 PolarHBondContact ND2-OG1 3.44Å; N357-T491 PolarHBondContact OD1-N 3.25Å; N357-T491 VanDerWaalsContact OD1-N 3.11Å; N357-T491 PolarHBondContact OD1-OG1 3.42Å; D487-T491 VanDerWaalsContact O-CB 3.29Å; D487-T491 WeakPolarHBondContact O-CB 3.3Å; D487-T491 PolarHBondContact O-N 3.45Å; D487-T491 PolarHBondContact O-OG1 2.95Å; T491-A495 VanDerWaalsContact O-CB 3.28Å; T491-A495 WeakPolarHBondContact O-CB 3.43Å; T491-A495 PolarHBondContact O-N 3.17Å
492	G	97.1	Very high	93.9	Very high	23 Å²	23	27.8 Å²	27.8	24%	0.237	15%	0.145	C	C	.	.	H	α-helix	trans	-66.2	-43.2	-179.3	0	0	0	0	0	114.1	L488 L489 A495 L496	L488-G492 PolarHBondContact O-N 3.23Å; L489-G492 PolarHBondContact O-N 2.95Å; G492-A495 PolarHBondContact O-N 3Å; G492-L496 PolarHBondContact O-N 3.38Å
493	L	97.5	Very high	93.7	Very high	29 Å²	29	33 Å²	33	15%	0.152	17%	0.172	C	C	.	.	H	α-helix	trans	-71.6	-35.8	178.2	-69.4	172.6	0	0	0	112	A448 L451 Q452 L489 L496 S497	A448-L493 HydrophobicContact CB-CB 3.89Å; L451-L493 HydrophobicContact CB-CD1 4.18Å; L451-L493 HydrophobicContact CD2-CD1 4.17Å; L451-L493 HydrophobicContact CD2-CD2 3.77Å; L451-L493 HydrophobicContact CG-CD1 4.05Å; Q452-L493 HydrophobicContact CB-CD1 3.94Å; L489-L493 WeakPolarHBondContact O-CB 3.4Å; L489-L493 WeakPolarHBondContact O-CG 3.47Å; L489-L493 PolarHBondContact O-N 3.25Å; L493-L496 PolarHBondContact O-N 2.87Å; L493-S497 WeakPolarHBondContact O-CB 3.25Å; L493-S497 PolarHBondContact O-N 3.14Å; L493-S497 PolarHBondContact O-OG 3.08Å
494	L	95.7	Very high	93.3	Very high	1 Å²	1	37.5 Å²	37.5	1%	0.005	20%	0.195	C	C	.	.	H	α-helix	trans	-63.1	-45.9	171.9	-174.5	63	0	0	0	110.5	M349 F352 I356 Y445 G490 L496 S497 F498	M349-L494 HydrophobicContact CG-CD2 3.61Å; M349-L494 HydrophobicContact CG-CG 3.93Å; M349-L494 HydrophobicContact SD-CD2 4.48Å; M349-L494 HydrophobicContact SD-CG 4.44Å; F352-L494 HydrophobicContact CB-CD1 4.29Å; F352-L494 HydrophobicContact CB-CD2 3.74Å; I356-L494 HydrophobicContact CD1-CB 4.32Å; I356-L494 HydrophobicContact CG2-CB 4.43Å; I356-L494 HydrophobicContact CG2-CD2 3.98Å; Y445-L494 HydrophobicContact CD2-CD1 3.66Å; Y445-L494 HydrophobicContact CE2-CD1 4.02Å; G490-L494 WeakPolarHBondContact O-CB 3.41Å; G490-L494 PolarHBondContact O-N 3.39Å; L494-L496 PolarHBondContact O-N 3.12Å; L494-S497 WeakPolarHBondContact O-CB 3.35Å; L494-S497 PolarHBondContact O-N 3.15Å; L494-F498 HydrophobicContact CD1-CD2 3.99Å; L494-F498 HydrophobicContact CD1-CE2 3.78Å; L494-F498 HydrophobicContact CG-CD2 4.08Å; L494-F498 HydrophobicContact CG-CE2 4.07Å; L494-F498 WeakPolarHBondContact O-CD2 3.42Å; L494-F498 PolarHBondContact O-N 3.46Å
495	A	94.8	Very high	92.3	Very high	14 Å²	14	39.5 Å²	39.5	12%	0.116	22%	0.216	C	C	.	.	H	α-helix	trans	-58.8	-44.5	176.1	0	0	0	0	0	113.2	I336 T340 M349 T491 G492 S497 F498 H499	I336-A495 HydrophobicContact CG2-CB 3.73Å; T340-A495 HydrophobicContact CG2-CB 3.71Å; M349-A495 VanDerWaalsContact CE-CA 3.42Å; M349-A495 HydrophobicContact CE-CB 3.86Å; M349-A495 HydrophobicContact SD-CB 4.03Å; T491-A495 VanDerWaalsContact O-CB 3.28Å; T491-A495 WeakPolarHBondContact O-CB 3.43Å; T491-A495 PolarHBondContact O-N 3.17Å; G492-A495 PolarHBondContact O-N 3Å; A495-S497 VanDerWaalsContact C-N 3.28Å; A495-S497 PolarHBondContact O-N 3.4Å; A495-F498 PolarHBondContact O-N 2.81Å; A495-H499 WeakPolarHBondContact O-CB 3.5Å; A495-H499 PolarHBondContact O-N 3.31Å
496	L	94.4	Very high	90.8	Very high	101 Å²	101	39.6 Å²	39.6	53%	0.529	22%	0.216	S	C	.	.	H	α-helix	trans	-61	-39.5	174.2	-178.4	62.2	0	0	0	111.8	G492 L493 L494 H499 V500	G492-L496 PolarHBondContact O-N 3.38Å; L493-L496 PolarHBondContact O-N 2.87Å; L494-L496 PolarHBondContact O-N 3.12Å; L496-H499 PolarHBondContact O-N 2.97Å; L496-V500 HydrophobicContact CD1-CG2 4.21Å; L496-V500 HydrophobicContact CG-CG2 4.46Å; L496-V500 VanDerWaalsContact O-CG2 3.29Å; L496-V500 WeakPolarHBondContact O-CG2 3.38Å; L496-V500 PolarHBondContact O-N 3.3Å
497	S	92.7	Very high	89	Confident	12 Å²	12	48.7 Å²	48.7	8%	0.084	25%	0.251	C	S	.	.	H	α-helix	trans	-62.9	-48.3	178.7	-60.8	0	0	0	0	111.7	A448 L493 L494 A495 H499 V500 L501	A448-S497 WeakPolarHBondContact CB-OG 3.4Å; L493-S497 WeakPolarHBondContact O-CB 3.25Å; L493-S497 PolarHBondContact O-N 3.14Å; L493-S497 PolarHBondContact O-OG 3.08Å; L494-S497 WeakPolarHBondContact O-CB 3.35Å; L494-S497 PolarHBondContact O-N 3.15Å; A495-S497 VanDerWaalsContact C-N 3.28Å; A495-S497 PolarHBondContact O-N 3.4Å; S497-H499 VanDerWaalsContact C-N 3.34Å; S497-H499 PolarHBondContact O-N 2.63Å; S497-V500 PolarHBondContact O-N 3.27Å; S497-L501 WeakPolarHBondContact O-CB 3.14Å; S497-L501 VanDerWaalsContact O-CG 3.24Å; S497-L501 WeakPolarHBondContact O-CG 3.26Å; S497-L501 PolarHBondContact O-N 3.28Å
498	F	90.8	Very high	87	Confident	14 Å²	14	50.6 Å²	50.6	6%	0.061	26%	0.261	C	S	.	.	H	α-helix	trans	-60.4	-42.6	174.7	-91.2	-92.4	0	0	0	112.2	F346 M349 F352 T435 F441 L494 A495 V500 L501 W502	F346-F498 HydrophobicContact CD1-CB 3.71Å; F346-F498 HydrophobicContact CD1-CD1 4.14Å; F346-F498 HydrophobicContact CD1-CG 4.38Å; F346-F498 HydrophobicContact CE1-CB 4.18Å; F346-F498 WeakPolarHBondContact CE1-O 3.46Å; F346-F498 HydrophobicContact CG-CB 4.49Å; M349-F498 HydrophobicContact CB-CD2 4.44Å; M349-F498 HydrophobicContact CB-CE2 4.22Å; M349-F498 HydrophobicContact CB-CZ 4.4Å; M349-F498 HydrophobicContact CE-CB 3.89Å; M349-F498 HydrophobicContact CE-CD2 3.97Å; M349-F498 HydrophobicContact CE-CG 3.99Å; M349-F498 HydrophobicContact CG-CD2 4.39Å; M349-F498 HydrophobicContact CG-CE2 4.34Å; F352-F498 HydrophobicContact CD2-CE2 4.11Å; F352-F498 AromaticContact CD2-CZ 3.82Å; F352-F498 HydrophobicContact CD2-CZ 3.82Å; F352-F498 HydrophobicContact CE2-CZ 4.09Å; T435-F498 HydrophobicContact CG2-CE1 4.13Å; F441-F498 HydrophobicContact CE2-CD2 4.42Å; F441-F498 HydrophobicContact CE2-CE1 4.19Å; F441-F498 AromaticContact CE2-CE2 3.67Å; F441-F498 HydrophobicContact CE2-CE2 3.67Å; F441-F498 AromaticContact CE2-CZ 3.54Å; F441-F498 HydrophobicContact CE2-CZ 3.54Å; F441-F498 HydrophobicContact CZ-CE2 4.2Å; F441-F498 HydrophobicContact CZ-CZ 4.11Å; L494-F498 HydrophobicContact CD1-CD2 3.99Å; L494-F498 HydrophobicContact CD1-CE2 3.78Å; L494-F498 HydrophobicContact CG-CD2 4.08Å; L494-F498 HydrophobicContact CG-CE2 4.07Å; L494-F498 WeakPolarHBondContact O-CD2 3.42Å; L494-F498 PolarHBondContact O-N 3.46Å; A495-F498 PolarHBondContact O-N 2.81Å; F498-V500 PolarHBondContact O-N 3.46Å; F498-L501 PolarHBondContact O-N 2.97Å; F498-W502 WeakPolarHBondContact O-CB 3.44Å; F498-W502 PolarHBondContact O-N 3.12Å
499	H	91.1	Very high	84.6	Confident	86 Å²	86	51.1 Å²	51.1	40%	0.398	27%	0.266	S	S	.	.	H	α-helix	trans	-63	-43	177.6	-169.8	69.3	0	0	0	112.4	F346 A495 L496 S497 W502 L503	F346-H499 AromaticContact CZ-ND1 3.94Å; A495-H499 WeakPolarHBondContact O-CB 3.5Å; A495-H499 PolarHBondContact O-N 3.31Å; L496-H499 PolarHBondContact O-N 2.97Å; S497-H499 VanDerWaalsContact C-N 3.34Å; S497-H499 PolarHBondContact O-N 2.63Å; H499-W502 PolarHBondContact O-N 3.5Å; H499-L503 WeakPolarHBondContact O-CG 3.45Å; H499-L503 PolarHBondContact O-N 3.47Å
500	V	90.7	Very high	82	Confident	42 Å²	42	56.6 Å²	56.6	26%	0.255	30%	0.296	S	S	.	.	H	α-helix	trans	-67.2	-40.8	177.1	172.5	0	0	0	0	111.5	F444 L496 S497 F498 W502 L503 I504	F444-V500 HydrophobicContact CD1-CG1 4.32Å; F444-V500 HydrophobicContact CE1-CB 4.26Å; F444-V500 HydrophobicContact CE1-CG1 3.5Å; F444-V500 VanDerWaalsContact CE1-CG1 3.5Å; F444-V500 HydrophobicContact CZ-CG1 3.7Å; L496-V500 HydrophobicContact CD1-CG2 4.21Å; L496-V500 HydrophobicContact CG-CG2 4.46Å; L496-V500 VanDerWaalsContact O-CG2 3.29Å; L496-V500 WeakPolarHBondContact O-CG2 3.38Å; L496-V500 PolarHBondContact O-N 3.3Å; S497-V500 PolarHBondContact O-N 3.27Å; F498-V500 PolarHBondContact O-N 3.46Å; V500-W502 VanDerWaalsContact C-N 3.33Å; V500-W502 PolarHBondContact O-N 3Å; V500-L503 PolarHBondContact O-N 3.31Å; V500-I504 HydrophobicContact CG1-CD1 3.67Å; V500-I504 HydrophobicContact CG1-CG1 4.33Å; V500-I504 VanDerWaalsContact O-CG1 3.32Å; V500-I504 WeakPolarHBondContact O-CG1 3.28Å; V500-I504 PolarHBondContact O-N 2.98Å
501	L	88.4	Confident	79.1	Confident	9 Å²	9	60.8 Å²	60.8	5%	0.047	32%	0.321	C	S	.	.	H	α-helix	trans	-59.7	-44.3	175.3	-74.8	166.5	0	0	0	111.8	I440 F441 F444 S497 F498 L503 I504 G505 D506	I440-L501 HydrophobicContact CB-CD2 4.37Å; I440-L501 HydrophobicContact CG2-CD2 3.58Å; F441-L501 HydrophobicContact CB-CD1 4.32Å; F441-L501 HydrophobicContact CD2-CD1 3.57Å; F441-L501 HydrophobicContact CE2-CD1 4.34Å; F441-L501 HydrophobicContact CG-CD1 4.39Å; F444-L501 HydrophobicContact CB-CD1 4.29Å; F444-L501 HydrophobicContact CB-CD2 4.43Å; F444-L501 HydrophobicContact CB-CG 4.33Å; F444-L501 HydrophobicContact CD2-CD2 3.55Å; F444-L501 HydrophobicContact CD2-CG 4.09Å; F444-L501 HydrophobicContact CE2-CD2 4.09Å; F444-L501 HydrophobicContact CG-CD2 4.19Å; F444-L501 HydrophobicContact CG-CG 4.26Å; S497-L501 WeakPolarHBondContact O-CB 3.14Å; S497-L501 VanDerWaalsContact O-CG 3.24Å; S497-L501 WeakPolarHBondContact O-CG 3.26Å; S497-L501 PolarHBondContact O-N 3.28Å; F498-L501 PolarHBondContact O-N 2.97Å; L501-L503 VanDerWaalsContact C-N 3.33Å; L501-L503 PolarHBondContact O-N 3.05Å; L501-I504 PolarHBondContact O-N 3.3Å; L501-G505 PolarHBondContact O-N 2.98Å; L501-D506 HydrophobicContact CD2-CB 4.45Å; L501-D506 PolarHBondContact O-N 3.26Å
502	W	85.7	Confident	75.9	Confident	113 Å²	113	63.8 Å²	63.8	43%	0.428	35%	0.352	S	S	.	.	H	α-helix	trans	-60.8	-40.8	174.9	-178.8	87.4	0	0	0	112.3	N345 F346 F498 H499 V500 G505	N345-W502 PolarHBondContact OD1-NE1 3.15Å; F346-W502 HydrophobicContact CE1-CB 3.78Å; F346-W502 HydrophobicContact CE1-CG 4.18Å; F346-W502 HydrophobicContact CZ-CB 4.22Å; F346-W502 HydrophobicContact CZ-CG 4.28Å; F498-W502 WeakPolarHBondContact O-CB 3.44Å; F498-W502 PolarHBondContact O-N 3.12Å; H499-W502 PolarHBondContact O-N 3.5Å; V500-W502 VanDerWaalsContact C-N 3.33Å; V500-W502 PolarHBondContact O-N 3Å; W502-G505 PolarHBondContact O-N 3.02Å
503	L	87.4	Confident	72.7	Confident	109 Å²	109	74.2 Å²	74.2	57%	0.571	40%	0.402	S	S	*	.	H	α-helix	trans	-67.1	-35.3	175.8	-71.7	173.8	0	0	0	113.5	H499 V500 L501 G505	H499-L503 WeakPolarHBondContact O-CG 3.45Å; H499-L503 PolarHBondContact O-N 3.47Å; V500-L503 PolarHBondContact O-N 3.31Å; L501-L503 VanDerWaalsContact C-N 3.33Å; L501-L503 PolarHBondContact O-N 3.05Å; L503-G505 PolarHBondContact O-N 2.76Å
504	I	84.7	Confident	71.4	Confident	100 Å²	100	76.5 Å²	76.5	51%	0.513	41%	0.414	S	S	.	.	H	α-helix	trans	-71.9	-18.2	177.9	-69.1	168.3	0	0	0	111.3	F444 V500 L501	F444-I504 HydrophobicContact CE2-CD1 3.83Å; F444-I504 HydrophobicContact CZ-CD1 3.6Å; V500-I504 HydrophobicContact CG1-CD1 3.67Å; V500-I504 HydrophobicContact CG1-CG1 4.33Å; V500-I504 VanDerWaalsContact O-CG1 3.32Å; V500-I504 WeakPolarHBondContact O-CG1 3.28Å; V500-I504 PolarHBondContact O-N 2.98Å; L501-I504 PolarHBondContact O-N 3.3Å
505	G	73.1	Confident	70.2	Confident	41 Å²	41	80.4 Å²	80.4	42%	0.423	44%	0.436	S	S	.	.	T	Hydrogen-bonded Turn	trans	84.2	20.6	178.6	0	0	0	0	0	113.4	L501 W502 L503 R507	L501-G505 PolarHBondContact O-N 2.98Å; W502-G505 PolarHBondContact O-N 3.02Å; L503-G505 PolarHBondContact O-N 2.76Å; G505-R507 PolarHBondContact O-N 3.13Å
506	D	65.3	Low	68.8	Low	43 Å²	43	84.1 Å²	84.1	23%	0.23	45%	0.454	C	S	.	.			trans	-70.5	69.4	159	-157.1	31.6	0	0	0	106.9	T438 L501 D508	T438-D506 PolarHBondContact OG1-OD2 3.27Å; L501-D506 HydrophobicContact CD2-CB 4.45Å; L501-D506 PolarHBondContact O-N 3.26Å; D506-D508 PolarHBondContact O-N 2.66Å
507	R	57.5	Low	67.3	Low	192 Å²	192	83.1 Å²	83.1	73%	0.725	45%	0.449	S	S	*	.			trans	-79.8	60.6	-177.5	-66.1	-178.5	177.7	168.2	-1.4	108.6	G505 T509	G505-R507 PolarHBondContact O-N 3.13Å; R507-T509 PolarHBondContact O-N 3.12Å
508	D	52.5	Low	65.7	Low	50 Å²	50	87.6 Å²	87.6	27%	0.267	47%	0.472	S	S	.	.			trans	-69.9	68.8	158.9	-85.6	-62.8	0	0	0	108.7	T436 T438 D506	T436-D508 PolarHBondContact OG1-OD1 3.26Å; T436-D508 PolarHBondContact OG1-OD2 3.13Å; T438-D508 WeakPolarHBondContact CG2-OD2 3.45Å; D506-D508 PolarHBondContact O-N 2.66Å
509	T	46.6	Very low	64	Low	57 Å²	57	92.5 Å²	92.5	35%	0.35	50%	0.5	S	S	.	.			trans	-109.1	46.1	160.9	55.8	0	0	0	0	107.6	R507 V511 G512	R507-T509 PolarHBondContact O-N 3.12Å; T509-V511 PolarHBondContact O-N 3.23Å; T509-G512 PolarHBondContact O-N 3.01Å
510	D	43	Very low	62.1	Low	153 Å²	153	92.9 Å²	92.9	82%	0.818	51%	0.507	S	S	*	.			trans	-71.9	33.2	160.3	-110.5	12.4	0	0	0	111.2
511	V	35.4	Very low	59.9	Low	87 Å²	87	96.8 Å²	96.8	53%	0.527	53%	0.526	S	S	.	.			trans	-133	65.7	162.3	-81.2	0	0	0	0	106	H434 T509	H434-V511 HydrophobicContact CB-CG1 3.95Å; H434-V511 HydrophobicContact CB-CG2 4.24Å; T509-V511 PolarHBondContact O-N 3.23Å
512	G	28.9	Very low	57.5	Low	63 Å²	63	104.2 Å²	104.2	65%	0.649	57%	0.566	S	S	*	*			trans	-156.2	29.2	-176.3	0	0	0	0	0	112	T509	T509-G512 PolarHBondContact O-N 3.01Å
513	D	29.9	Very low	54.9	Low	242 Å²	242	103.4 Å²	103.4	100%	1.294	58%	0.579	S	S	*	*			trans	-136.8	0	158	-91.7	-22.9	0	0	0	108.7

Retrieved 513 of 513 residues in 4094.1 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).