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Transcription factor AP-2 gamma

Sequence-specific DNA-binding transcription factor that interacts with cellular enhancer elements to regulate transcription of selected genes, and which plays a key role in early embryonic development^1,2. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions^3,4. TFAP2C plays a key role in early embryonic development by regulating both inner cell mass (ICM) and trophectoderm differentiation⁵. At the 8-cell stage, during morula development, controls expression of cell-polarity genes⁶. Upon trophoblast commitment, binds to late trophectoderm genes in blastocysts together with CDX2, and later to extra-embryonic ectoderm genes together with SOX2⁷. Binds to both closed and open chromatin with other transcription factors⁸.

AlphaFold DB , UniProt , Accession Q61312, Species MOUSE (Mus musculus, Mouse), Gene Tfap2c, Length 449 aa.

Structure Viewer

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	41.3	Very low	44.2	Very low	226 Å²	226	166.1 Å²	166.1	100%	1.113	80%	0.802	S	S	*	*				0	108.8	0	-67	173	-176.6	0	0	107.4
2	L	46.5	Very low	44.1	Very low	174 Å²	174	164.1 Å²	164.1	91%	0.911	79%	0.791	S	S	*	*			trans	156.5	59.5	178.5	-95.3	150.1	0	0	0	105.8
3	W	41.4	Very low	43.6	Very low	207 Å²	207	166.5 Å²	166.5	78%	0.784	80%	0.8	S	S	*	*				51.1	101.1	89.3	-76.1	93.2	0	0	0	114.6
4	K	41.7	Very low	43.5	Very low	164 Å²	164	164.6 Å²	164.6	71%	0.713	80%	0.797	S	S	*	*			trans	31.1	108.9	145.1	-62.4	-178.4	179.2	-179.6	0	118.1
5	I	56.7	Low	43.3	Very low	177 Å²	177	162.3 Å²	162.3	91%	0.908	80%	0.802	S	S	*	*			trans	-114.9	104	135.1	-61.8	177.5	0	0	0	106.4
6	T	45.2	Very low	43	Very low	95 Å²	95	161.6 Å²	161.6	58%	0.583	80%	0.796	S	S	*	*			trans	-117.5	159.3	162.5	49.9	0	0	0	0	108.7
7	D	44.1	Very low	42.9	Very low	141 Å²	141	162 Å²	162	75%	0.754	80%	0.802	S	S	*	*			trans	88	143.6	158.2	-46.8	-52.5	0	0	0	118.5
8	N	41.7	Very low	42.8	Very low	154 Å²	154	164.4 Å²	164.4	82%	0.824	80%	0.801	S	S	*	*			trans	68.4	72.4	172	-62.7	-8.2	0	0	0	119.2
9	V	43	Very low	43.1	Very low	117 Å²	117	165.8 Å²	165.8	71%	0.709	81%	0.805	S	S	*	*			trans	-121.2	94.1	134	-171.1	0	0	0	0	108.9	Y11	V9-Y11 HydrophobicContact CG1-CD2 3.56Å; V9-Y11 HydrophobicContact CG1-CE2 3.47Å; V9-Y11 VanDerWaalsContact CG1-CE2 3.47Å; V9-Y11 PolarHBondContact O-N 3.3Å
10	K	41.7	Very low	42.8	Very low	163 Å²	163	165.1 Å²	165.1	71%	0.709	81%	0.805	S	S	*	*			trans	-80.9	97.1	167.2	-176.5	-159.8	179.7	-146.2	0	106.8	E12	K10-E12 IonicContact NZ-OE1 3.81Å; K10-E12 PolarHBondContact NZ-OE1 3.39Å
11	Y	43.4	Very low	42.8	Very low	209 Å²	209	163 Å²	163	82%	0.82	81%	0.808	S	S	*	*			trans	-73.3	125.4	163.8	-90.2	-82.8	0	0	0	108	V9	V9-Y11 HydrophobicContact CG1-CD2 3.56Å; V9-Y11 HydrophobicContact CG1-CE2 3.47Å; V9-Y11 VanDerWaalsContact CG1-CE2 3.47Å; V9-Y11 PolarHBondContact O-N 3.3Å
12	E	42.4	Very low	42.7	Very low	142 Å²	142	158.3 Å²	158.3	66%	0.664	80%	0.797	S	S	*	*			trans	-75.6	144.3	169.3	-55.8	-148.5	122	0	0	109.7	K10 D14	K10-E12 IonicContact NZ-OE1 3.81Å; K10-E12 PolarHBondContact NZ-OE1 3.39Å; E12-D14 PolarHBondContact O-N 3.06Å
13	E	38.2	Very low	42.6	Very low	195 Å²	195	155.9 Å²	155.9	91%	0.911	79%	0.794	S	S	*	*			trans	-79	106.3	167.6	-71.1	174.7	124.4	0	0	107.7
14	D	42	Very low	42.6	Very low	141 Å²	141	154.2 Å²	154.2	75%	0.754	80%	0.801	S	S	*	*			trans	-152.4	118.4	159.1	-110.2	-31.7	0	0	0	110.3	E12	E12-D14 PolarHBondContact O-N 3.06Å
15	C	40	Very low	42.7	Very low	129 Å²	129	150.3 Å²	150.3	87%	0.872	81%	0.807	S	S	*	*			trans	-168.5	111.6	157.6	-96.3	0	0	0	0	106.3
16	E	38.1	Very low	42	Very low	151 Å²	151	149.3 Å²	149.3	71%	0.706	80%	0.804	S	S	*	*	P	Polyproline II helix	trans	-70.9	146.7	-168.8	-54.8	145.9	94.5	0	0	112.8
17	D	41.8	Very low	42.2	Very low	169 Å²	169	149 Å²	149	90%	0.904	80%	0.803	S	S	*	*	P	Polyproline II helix	trans	-99	120.5	151.5	-113.4	-41	0	0	0	107.8
18	R	40.4	Very low	42.3	Very low	206 Å²	206	153.8 Å²	153.8	78%	0.777	81%	0.811	S	S	*	*	P	Polyproline II helix	trans	-83.6	131.7	-176.4	-71.6	179	175.1	152	1.1	110.5
19	H	48.7	Very low	42.9	Very low	190 Å²	190	153.4 Å²	153.4	88%	0.88	81%	0.807	S	S	*	*			trans	-113.7	117.5	162.7	-109.2	-74.1	0	0	0	109.6
20	D	38.6	Very low	43.2	Very low	151 Å²	151	152.5 Å²	152.5	81%	0.807	80%	0.803	S	S	*	*			trans	-64.3	137.9	173.9	-76.3	-58.8	0	0	0	111.9
21	S	43	Very low	43.2	Very low	123 Å²	123	152.7 Å²	152.7	86%	0.86	81%	0.806	S	S	*	*			trans	-158.2	101.3	163	-79.8	0	0	0	0	110.6
22	S	39.1	Very low	43.6	Very low	127 Å²	127	151.3 Å²	151.3	89%	0.888	81%	0.812	S	S	*	*			trans	-68.5	129.1	-179	-55.1	0	0	0	0	113.3
23	S	43.1	Very low	43.5	Very low	122 Å²	122	149.6 Å²	149.6	85%	0.853	82%	0.816	S	S	*	*			trans	-162.2	130.2	156.2	-171.6	0	0	0	0	113
24	N	41.1	Very low	43.5	Very low	172 Å²	172	145.8 Å²	145.8	92%	0.92	81%	0.811	S	S	*	*			trans	-47.3	143.7	-176.2	-76.7	-27.3	0	0	0	117.8
25	G	45	Very low	43.7	Very low	82 Å²	82	145.3 Å²	145.3	85%	0.845	82%	0.815	S	S	*	*			trans	167.8	98.8	157.7	0	0	0	0	0	115.1
26	N	42.1	Very low	43.9	Very low	157 Å²	157	142.8 Å²	142.8	84%	0.84	81%	0.812	S	S	*	*			trans	-118.4	177.2	-176.3	-149.6	21.2	0	0	0	110.8
27	P	49.6	Very low	44.1	Very low	87 Å²	87	143.5 Å²	143.5	57%	0.565	82%	0.815	S	S	*	*				-128	-173.2	-90	41.3	-26.2	0	0	0	114.8
28	R	44.8	Very low	44.2	Very low	243 Å²	243	142.7 Å²	142.7	92%	0.917	81%	0.806	S	S	*	*			trans	-170	102	153	-103.7	159.4	-177.1	167.5	2	110.6
29	I	54.1	Low	44.4	Very low	146 Å²	146	140.6 Å²	140.6	75%	0.749	81%	0.809	S	S	*	*				61	134.9	76.7	-69.7	-178.6	0	0	0	113.5
30	P	50.3	Low	44	Very low	97 Å²	97	142.7 Å²	142.7	63%	0.63	81%	0.81	S	S	*	*			cis	-155.7	-166.7	-24.9	46.1	-25.2	0	0	0	117.6
31	H	42.5	Very low	44.3	Very low	167 Å²	167	141 Å²	141	77%	0.773	81%	0.811	S	S	*	*			trans	59.6	127.7	145.2	-73.8	-64	0	0	0	124.9
32	L	50.2	Low	44.5	Very low	180 Å²	180	140.8 Å²	140.8	94%	0.942	81%	0.806	S	S	*	*			trans	-156.1	158.7	130.9	-105.5	167	0	0	0	109.8
33	S	40.8	Very low	44.8	Very low	107 Å²	107	139.4 Å²	139.4	75%	0.748	80%	0.802	S	S	*	*			trans	-122	151.8	-155.4	-57.7	0	0	0	0	117.4
34	S	37.8	Very low	45.1	Very low	114 Å²	114	139 Å²	139	80%	0.797	80%	0.797	S	S	*	*			trans	-53.4	-176.1	164.5	-80.4	0	0	0	0	117.1
35	P	46	Very low	45.3	Very low	131 Å²	131	136.6 Å²	136.6	85%	0.851	79%	0.791	S	S	*	*			cis	-136.2	-176	-30.1	33.1	-13.2	0	0	0	114.2
36	G	45.3	Very low	45.4	Very low	77 Å²	77	140.2 Å²	140.2	79%	0.794	79%	0.79	S	S	*	*			trans	-158.9	133	170.4	0	0	0	0	0	115.7
37	Q	41.4	Very low	45.2	Very low	165 Å²	165	138.1 Å²	138.1	77%	0.771	79%	0.787	S	S	*	*			trans	-66.3	155.2	-168.4	-59	165.7	-9.1	0	0	116.7
38	H	43.9	Very low	45	Very low	153 Å²	153	142 Å²	142	71%	0.708	80%	0.798	S	S	*	*				161.1	132.3	113.4	-88.6	-72.4	0	0	0	117.1
39	L	45.4	Very low	44.8	Very low	161 Å²	161	136.7 Å²	136.7	84%	0.843	79%	0.792	S	S	*	*			trans	73.2	132.2	142.2	-64.9	162.9	0	0	0	122.9
40	Y	39.1	Very low	44	Very low	234 Å²	234	133.6 Å²	133.6	92%	0.918	80%	0.797	S	S	*	*			trans	-87.9	159.1	175.3	-81.4	-103.8	0	0	0	113
41	S	46.2	Very low	43.6	Very low	117 Å²	117	135.8 Å²	135.8	82%	0.818	81%	0.808	S	S	*	*			trans	-158.8	124.3	152.5	-160.2	0	0	0	0	112.3
42	P	47.1	Very low	43.6	Very low	118 Å²	118	131.6 Å²	131.6	77%	0.766	80%	0.802	S	S	*	*	P	Polyproline II helix	trans	-95.8	148.7	173.8	35.7	-31.2	0	0	0	112.6
43	A	45.7	Very low	43.1	Very low	97 Å²	97	132.2 Å²	132.2	80%	0.802	80%	0.8	S	S	*	*	P	Polyproline II helix	trans	-83.5	149	177.1	0	0	0	0	0	112.7
44	P	48.7	Very low	43.4	Very low	114 Å²	114	137.4 Å²	137.4	74%	0.74	81%	0.805	S	S	*	*	P	Polyproline II helix	trans	-84.7	158.8	-176.5	35	-36.3	0	0	0	113.4
45	P	45.2	Very low	43.9	Very low	121 Å²	121	140.3 Å²	140.3	79%	0.786	81%	0.806	S	S	*	*	P	Polyproline II helix	trans	-78.7	137.1	177.2	32.2	-33.9	0	0	0	112.1
46	L	47.2	Very low	44.9	Very low	159 Å²	159	139.1 Å²	139.1	83%	0.832	80%	0.798	S	S	*	*	P	Polyproline II helix	trans	-83.5	116.4	173.1	-74.2	171.7	0	0	0	111
47	S	37.9	Very low	46	Very low	112 Å²	112	140.9 Å²	140.9	78%	0.783	80%	0.795	S	S	*	*			trans	-94	113.7	168.6	-57.2	0	0	0	0	109.5
48	H	46.1	Very low	47.2	Very low	170 Å²	170	138.5 Å²	138.5	79%	0.787	79%	0.794	S	S	*	*			trans	-124.7	120.7	166.9	-86.2	-67.5	0	0	0	111.8
49	T	40.1	Very low	48.4	Very low	131 Å²	131	140.8 Å²	140.8	80%	0.804	80%	0.798	S	S	*	*			trans	-67.4	156.1	174.6	46	0	0	0	0	112
50	G	38.1	Very low	49.7	Very low	81 Å²	81	141.9 Å²	141.9	84%	0.835	80%	0.796	S	S	*	*			trans	-62.9	157.5	-166.7	0	0	0	0	0	116.6
51	V	40.7	Very low	51.2	Low	142 Å²	142	135.3 Å²	135.3	86%	0.861	78%	0.782	S	S	*	*			trans	-132.5	150.4	169.1	-169.8	0	0	0	0	108.1
52	A	42.6	Very low	52.2	Low	80 Å²	80	134.3 Å²	134.3	66%	0.661	77%	0.773	S	S	*	*			trans	-60.2	154	-159.7	0	0	0	0	0	117.3	Y54	A52-Y54 PolarHBondContact O-N 3.05Å
53	E	40.2	Very low	52.8	Low	193 Å²	193	134.5 Å²	134.5	90%	0.902	78%	0.775	S	S	*	*			trans	-58.7	102.8	171.1	-172.5	171.2	-168.9	0	0	111.8	Q55	E53-Q55 PolarHBondContact O-N 2.67Å
54	Y	46.5	Very low	52.7	Low	216 Å²	216	141 Å²	141	85%	0.847	78%	0.78	S	S	*	*			trans	-82.9	98.4	172.7	-96.5	-90.9	0	0	0	110.5	A52	A52-Y54 PolarHBondContact O-N 3.05Å
55	Q	49.6	Very low	52.8	Low	175 Å²	175	143.8 Å²	143.8	82%	0.818	78%	0.783	S	S	*	*	P	Polyproline II helix	trans	-68	123.2	171	-169	179.5	2.8	0	0	110.3	E53	E53-Q55 PolarHBondContact O-N 2.67Å
56	P	65.8	Low	52.4	Low	105 Å²	105	147.3 Å²	147.3	68%	0.682	79%	0.789	S	S	*	*	P	Polyproline II helix	trans	-71.8	145.9	177.9	28.7	-33.8	0	0	0	111.3
57	P	69.1	Low	52.2	Low	114 Å²	114	146.9 Å²	146.9	74%	0.74	79%	0.787	S	S	*	*	P	Polyproline II helix	trans	-67.3	152.5	178.7	28.5	-35	0	0	0	111.8	Y59	P57-Y59 PolarHBondContact O-N 3.46Å
58	P	65.3	Low	52.3	Low	115 Å²	115	146.1 Å²	146.1	75%	0.747	79%	0.787	S	S	*	*	P	Polyproline II helix	trans	-65.4	126.7	-175.2	26.2	-34.3	0	0	0	112	F60	P58-F60 PolarHBondContact O-N 2.71Å
59	Y	70.5	Confident	51.9	Low	201 Å²	201	148.6 Å²	148.6	79%	0.788	79%	0.791	S	S	*	*			trans	-79.9	113.8	-179.5	-173.3	-90.9	0	0	0	111.1	P57	P57-Y59 PolarHBondContact O-N 3.46Å
60	F	72.2	Confident	51.9	Low	184 Å²	184	147.7 Å²	147.7	81%	0.807	79%	0.791	S	S	*	*	P	Polyproline II helix	trans	-87.4	124.8	169.4	-95.8	-93.8	0	0	0	110.6	P58	P58-F60 PolarHBondContact O-N 2.71Å
61	P	71.4	Confident	51.8	Low	96 Å²	96	153.1 Å²	153.1	62%	0.623	79%	0.794	S	S	*	*	P	Polyproline II helix	trans	-71.8	141.2	175.3	29.7	-33.7	0	0	0	111.1
62	P	66.8	Low	51.8	Low	97 Å²	97	151.6 Å²	151.6	63%	0.63	79%	0.79	S	S	*	*	P	Polyproline II helix	trans	-69.9	151.2	176.3	29.6	-34.7	0	0	0	111.5
63	P	58.8	Low	51.5	Low	122 Å²	122	152.6 Å²	152.6	79%	0.792	80%	0.798	S	S	*	*	P	Polyproline II helix	trans	-69	139.2	-177.7	28.5	-34.8	0	0	0	111.9	Q65	P63-Q65 PolarHBondContact O-N 3.13Å; P63-Q65 VanDerWaalsContact O-N 3.16Å
64	Y	43.2	Very low	51.3	Low	234 Å²	234	150.6 Å²	150.6	92%	0.918	79%	0.794	S	S	*	*			trans	-64	111.6	174	-85.2	-95.7	0	0	0	111
65	Q	51.6	Low	51.1	Low	172 Å²	172	148.8 Å²	148.8	80%	0.804	79%	0.793	S	S	*	*			trans	-82.8	115.5	158.8	-74.5	-176.3	-21.6	0	0	108.9	P63 L67	P63-Q65 PolarHBondContact O-N 3.13Å; P63-Q65 VanDerWaalsContact O-N 3.16Å; Q65-L67 PolarHBondContact O-N 3.21Å
66	Q	37.3	Very low	50.7	Low	194 Å²	194	150.7 Å²	150.7	91%	0.907	79%	0.794	S	S	*	*			trans	-69.9	113.7	167.2	-70.3	-167.3	-47.6	0	0	109.1	A68	Q66-A68 PolarHBondContact O-N 3.22Å
67	L	42.9	Very low	49.5	Very low	151 Å²	151	150.9 Å²	150.9	79%	0.791	80%	0.797	S	S	*	*			trans	-74.7	114.8	166.7	-86.6	80.7	0	0	0	109	Q65 Y69	Q65-L67 PolarHBondContact O-N 3.21Å; L67-Y69 PolarHBondContact O-N 3.13Å
68	A	38.6	Very low	48.6	Very low	96 Å²	96	153.5 Å²	153.5	79%	0.793	80%	0.8	S	S	*	*			trans	-64.5	118.6	167.4	0	0	0	0	0	109.7	Q66 S70	Q66-A68 PolarHBondContact O-N 3.22Å; A68-S70 PolarHBondContact O-N 3.18Å
69	Y	39.3	Very low	47.9	Very low	221 Å²	221	155 Å²	155	87%	0.867	80%	0.8	S	S	*	*			trans	-78	104.9	170.3	-108.2	-93.2	0	0	0	109.3	L67 Q71	L67-Y69 PolarHBondContact O-N 3.13Å; Y69-Q71 PolarHBondContact O-N 3.24Å
70	S	40.5	Very low	46.6	Very low	113 Å²	113	148 Å²	148	79%	0.79	79%	0.789	S	S	*	*			trans	-66.6	115.2	162.1	-68.4	0	0	0	0	108.8	A68 S72	A68-S70 PolarHBondContact O-N 3.18Å; S70-S72 PolarHBondContact O-N 3.16Å
71	Q	35.5	Very low	45.3	Very low	195 Å²	195	145.9 Å²	145.9	91%	0.911	78%	0.782	S	S	*	*	P	Polyproline II helix	trans	-71.4	118.1	173.1	-66.4	-178.6	-0	0	0	109.8	Y69	Y69-Q71 PolarHBondContact O-N 3.24Å
72	S	40.8	Very low	44	Very low	109 Å²	109	145.1 Å²	145.1	76%	0.762	78%	0.784	S	S	*	*	P	Polyproline II helix	trans	-100.6	125	158.5	53.9	0	0	0	0	108.1	S70	S70-S72 PolarHBondContact O-N 3.16Å
73	A	34.9	Very low	42.9	Very low	102 Å²	102	149.9 Å²	149.9	84%	0.843	79%	0.79	S	S	*	*	P	Polyproline II helix	trans	-66.2	134.2	-172.7	0	0	0	0	0	112.7
74	D	37	Very low	42.4	Very low	151 Å²	151	147.6 Å²	147.6	81%	0.807	78%	0.782	S	S	*	*			trans	-147	142.9	160.8	-100.2	-44.2	0	0	0	110.9	Y76	D74-Y76 PolarHBondContact O-N 3.46Å
75	H	42.6	Very low	42.8	Very low	178 Å²	178	140.4 Å²	140.4	82%	0.824	77%	0.771	S	S	*	*	S	Bend	trans	-79	102.8	-171.1	-69.5	81.3	0	0	0	111.8
76	Y	40	Very low	42.8	Very low	214 Å²	214	136.1 Å²	136.1	84%	0.839	77%	0.765	S	S	*	*			trans	-173.8	48.3	154.2	-101.1	-63.1	0	0	0	113.3	D74 H78	D74-Y76 PolarHBondContact O-N 3.46Å; Y76-H78 PolarHBondContact O-N 3.03Å
77	S	40.9	Very low	43.4	Very low	109 Å²	109	133.9 Å²	133.9	76%	0.762	76%	0.756	S	S	*	*	G	3₁₀ helix	trans	-76.1	-7.9	-170.4	-52.9	0	0	0	0	116.9	L79	S77-L79 PolarHBondContact O-N 3.43Å
78	H	49.8	Very low	43.4	Very low	170 Å²	170	133.8 Å²	133.8	79%	0.787	76%	0.756	S	S	*	*	G	3₁₀ helix	trans	-85.8	6.8	-165	-140.7	-53.9	0	0	0	116.2	Y76	Y76-H78 PolarHBondContact O-N 3.03Å
79	L	51.1	Low	43.3	Very low	146 Å²	146	135.2 Å²	135.2	76%	0.764	76%	0.757	S	S	*	*	G	3₁₀ helix	trans	-105.6	-10.5	-178.2	-78.3	166.1	0	0	0	114.5	S77	S77-L79 PolarHBondContact O-N 3.43Å
80	G	43.1	Very low	43.4	Very low	53 Å²	53	131.9 Å²	131.9	55%	0.546	75%	0.754	S	S	.	*	S	Bend	trans	-78.3	-33.3	-177	0	0	0	0	0	114.6
81	E	44.4	Very low	43.4	Very low	141 Å²	141	135.1 Å²	135.1	66%	0.659	76%	0.756	S	S	*	*	H	α-helix	trans	-79.9	-23.1	-169.4	-72.3	155.2	147	0	0	113.3	Y83 A85	E81-Y83 VanDerWaalsContact C-N 3.28Å; E81-Y83 PolarHBondContact O-N 3.03Å; E81-A85 PolarHBondContact O-N 3.46Å
82	A	45.8	Very low	43.3	Very low	80 Å²	80	134.5 Å²	134.5	66%	0.661	75%	0.753	S	S	*	*	H	α-helix	trans	-66.9	-25.9	177	0	0	0	0	0	113.6
83	Y	42.7	Very low	43.4	Very low	196 Å²	196	135 Å²	135	77%	0.769	75%	0.754	S	S	*	*	H	α-helix	trans	-90.3	-29.2	-179.5	-139.7	-96.7	0	0	0	112.7	E81	E81-Y83 VanDerWaalsContact C-N 3.28Å; E81-Y83 PolarHBondContact O-N 3.03Å
84	A	49.2	Very low	43.6	Very low	74 Å²	74	134.3 Å²	134.3	61%	0.612	75%	0.748	S	S	*	*	H	α-helix	trans	-73.2	-30.9	175.7	0	0	0	0	0	112.7	A86	A84-A86 VanDerWaalsContact C-N 3.3Å; A84-A86 PolarHBondContact O-N 3.16Å
85	A	50.1	Low	43.5	Very low	83 Å²	83	131.3 Å²	131.3	69%	0.686	74%	0.744	S	S	*	*	T	Hydrogen-bonded Turn	trans	-72.8	-17.3	179.6	0	0	0	0	0	114.4	E81 M87	E81-A85 PolarHBondContact O-N 3.46Å; A85-M87 VanDerWaalsContact C-N 3.33Å
86	A	52.3	Low	43.4	Very low	82 Å²	82	130 Å²	130	68%	0.678	75%	0.749	S	S	*	*	T	Hydrogen-bonded Turn	trans	-83.1	-5.4	-178.4	0	0	0	0	0	114.2	A84	A84-A86 VanDerWaalsContact C-N 3.3Å; A84-A86 PolarHBondContact O-N 3.16Å
87	M	49.3	Very low	43.3	Very low	148 Å²	148	123.6 Å²	123.6	73%	0.729	75%	0.748	S	S	*	*	S	Bend	trans	-126	49.9	-173.4	-67.5	-161.6	158.5	0	0	113.3	A85	A85-M87 VanDerWaalsContact C-N 3.33Å
88	N	42.7	Very low	43	Very low	148 Å²	148	123.7 Å²	123.7	79%	0.791	75%	0.749	S	S	*	*			trans	-159.9	87.2	164.4	-105.5	-30.1	0	0	0	112.9	L90	N88-L90 PolarHBondContact O-N 3.18Å
89	P	37.8	Very low	42.4	Very low	126 Å²	126	124.6 Å²	124.6	82%	0.818	75%	0.754	S	S	*	*			trans	-94.7	48.5	179.2	38.3	-34.9	0	0	0	112.6
90	L	40.5	Very low	41.7	Very low	151 Å²	151	125.8 Å²	125.8	79%	0.791	76%	0.755	S	S	*	*			trans	-159.1	85	174.5	-149.5	74.8	0	0	0	114.3	N88	N88-L90 PolarHBondContact O-N 3.18Å
91	H	40.1	Very low	41.7	Very low	182 Å²	182	131.7 Å²	131.7	84%	0.843	77%	0.769	S	S	*	*			trans	-179.5	118.7	135.9	-102.2	71.7	0	0	0	111.4
92	Q	33.7	Very low	41.3	Very low	182 Å²	182	129.4 Å²	129.4	85%	0.85	77%	0.774	S	S	*	*			trans	-115.5	149.7	158	-108.8	-174.3	22.5	0	0	106.1
93	P	42.7	Very low	40.6	Very low	119 Å²	119	137.1 Å²	137.1	77%	0.773	79%	0.786	S	S	*	*				-151.1	162.6	71.6	39	-19.1	0	0	0	118.7
94	A	38.8	Very low	40.7	Very low	87 Å²	87	133.4 Å²	133.4	72%	0.719	79%	0.786	S	S	*	*			trans	49.7	95.5	140.1	0	0	0	0	0	122.4
95	A	36.7	Very low	40.1	Very low	88 Å²	88	132.9 Å²	132.9	73%	0.727	79%	0.787	S	S	*	*				62.5	142.1	110.8	0	0	0	0	0	124.2
96	T	38.9	Very low	39.4	Very low	150 Å²	150	140.8 Å²	140.8	92%	0.92	80%	0.799	S	S	*	*			trans	86.3	140.6	160.8	75.1	0	0	0	0	118.8
97	G	37.9	Very low	38.8	Very low	80 Å²	80	146 Å²	146	83%	0.825	81%	0.81	S	S	*	*			trans	117.2	80.7	166.4	0	0	0	0	0	116.1
98	S	34.6	Very low	38.1	Very low	112 Å²	112	144 Å²	144	78%	0.783	81%	0.811	S	S	*	*			trans	-72.3	132.8	168.8	53.7	0	0	0	0	112.7
99	Q	38.6	Very low	37.9	Very low	189 Å²	189	144.2 Å²	144.2	88%	0.883	81%	0.806	S	S	*	*				-176.6	162.6	114.2	-102.9	-166.8	14.2	0	0	113.4
100	Q	36.9	Very low	37.8	Very low	171 Å²	171	146.2 Å²	146.2	80%	0.799	81%	0.805	S	S	*	*			trans	-88.7	144.1	-177.3	-58.1	161	-35.6	0	0	111
101	Q	41.7	Very low	37.7	Very low	177 Å²	177	142.6 Å²	142.6	83%	0.827	80%	0.804	S	S	*	*				159	140.5	111.4	-83.1	-160	-6	0	0	114.1
102	A	36.2	Very low	37.5	Very low	92 Å²	92	139.5 Å²	139.5	76%	0.76	80%	0.803	S	S	*	*			trans	43.6	108.7	146.4	0	0	0	0	0	121.6
103	W	30.8	Very low	37.9	Very low	242 Å²	242	136.5 Å²	136.5	92%	0.917	80%	0.802	S	S	*	*			trans	-72.2	176.8	143.9	-71.1	80.9	0	0	0	110.6
104	P	45.7	Very low	37.5	Very low	119 Å²	119	139.5 Å²	139.5	77%	0.773	81%	0.81	S	S	*	*			cis	-135.9	170.3	0.5	32.2	-11.5	0	0	0	116.8
105	G	36.7	Very low	37.6	Very low	62 Å²	62	139.8 Å²	139.8	64%	0.639	81%	0.813	S	S	*	*				122.8	123.4	123	0	0	0	0	0	119.7
106	R	34	Very low	37.7	Very low	250 Å²	250	139.8 Å²	139.8	94%	0.943	81%	0.807	S	S	*	*			trans	67.1	149.3	169.1	-54.4	-174.9	-178.2	-85	0.7	113.4
107	Q	39.9	Very low	37.8	Very low	192 Å²	192	139.7 Å²	139.7	90%	0.897	80%	0.797	S	S	*	*			cis	-146.2	162.1	28.9	-172.4	166.9	-4.3	0	0	112.3
108	S	35.1	Very low	37.9	Very low	106 Å²	106	144 Å²	144	74%	0.741	80%	0.795	S	S	*	*			trans	-83.7	162.3	-178.2	-166.3	0	0	0	0	113.2
109	Q	39.5	Very low	38.2	Very low	151 Å²	151	143.4 Å²	143.4	71%	0.706	79%	0.79	S	S	*	*			trans	107.7	105.8	137.2	-153.8	163.1	6.6	0	0	119.7
110	E	35.6	Very low	38.3	Very low	169 Å²	169	145.9 Å²	145.9	79%	0.79	79%	0.792	S	S	*	*			trans	49.1	129.7	137.2	-59	171.4	141.2	0	0	121.7
111	G	37.2	Very low	38.5	Very low	75 Å²	75	142.8 Å²	142.8	77%	0.773	79%	0.789	S	S	*	*			trans	-177.1	62.3	175.1	0	0	0	0	0	118.4
112	S	37.4	Very low	38.5	Very low	116 Å²	116	138.5 Å²	138.5	81%	0.811	78%	0.784	S	S	*	*			trans	65.3	131.4	146.5	-153.6	0	0	0	0	123
113	S	40.9	Very low	38.7	Very low	119 Å²	119	139.2 Å²	139.2	83%	0.832	78%	0.783	S	S	*	*			trans	126.3	123.4	130.7	72.9	0	0	0	0	117.1
114	L	35	Very low	39.4	Very low	182 Å²	182	135.5 Å²	135.5	95%	0.953	78%	0.78	S	S	*	*			trans	-136.1	115.1	-179.1	-108.7	165.5	0	0	0	108.1
115	A	39.6	Very low	39.2	Very low	93 Å²	93	136 Å²	136	77%	0.769	78%	0.776	S	S	*	*			trans	171.9	141.4	171.1	0	0	0	0	0	109.2
116	S	39.1	Very low	39.6	Very low	88 Å²	88	138.7 Å²	138.7	62%	0.615	78%	0.781	S	S	*	*			cis	-167.2	173.1	-8.9	-71.8	0	0	0	0	111.8
117	H	41.9	Very low	39.8	Very low	149 Å²	149	134.4 Å²	134.4	69%	0.69	77%	0.772	S	S	*	*			trans	78	109.6	141.8	-63.5	-43.7	0	0	0	123.5
118	H	39.9	Very low	40	Very low	170 Å²	170	133.8 Å²	133.8	79%	0.787	77%	0.773	S	S	*	*				66.2	147.9	127.1	-53.4	-43.6	0	0	0	120
119	S	39.6	Very low	40.2	Very low	99 Å²	99	134.7 Å²	134.7	69%	0.692	78%	0.779	S	S	*	*			cis	-162.2	151.2	23	55.6	0	0	0	0	114.6
120	R	41.1	Very low	40.2	Very low	241 Å²	241	130.8 Å²	130.8	91%	0.909	78%	0.78	S	S	*	*			trans	55.1	153.2	143.8	-63.5	177.7	-178.8	-148.8	-0.8	120
121	S	41.2	Very low	40.4	Very low	106 Å²	106	131.1 Å²	131.1	74%	0.741	79%	0.786	S	S	*	*			cis	-155.4	158.2	17.7	-150.8	0	0	0	0	114.7
122	A	42.6	Very low	40.4	Very low	87 Å²	87	136.7 Å²	136.7	72%	0.719	79%	0.792	S	S	*	*			trans	9.9	155.4	149	0	0	0	0	0	121.4
123	S	40.9	Very low	40.4	Very low	107 Å²	107	134.9 Å²	134.9	75%	0.748	79%	0.792	S	S	*	*			cis	-176.3	169.4	12.8	24.7	0	0	0	0	108
124	L	45.3	Very low	40.3	Very low	164 Å²	164	132.9 Å²	132.9	86%	0.859	79%	0.789	S	S	*	*			cis	-160.1	-173.1	-1.1	-118.9	168.2	0	0	0	109.5
125	I	41.4	Very low	40.5	Very low	131 Å²	131	129.5 Å²	129.5	67%	0.672	78%	0.781	S	S	*	*			trans	-135.6	164.7	168	-26.8	178.4	0	0	0	107.9
126	P	44	Very low	40.4	Very low	117 Å²	117	131.3 Å²	131.3	76%	0.76	78%	0.782	S	S	*	*				-152.1	170.2	87	38.8	-18.3	0	0	0	117.8
127	H	37.8	Very low	40.3	Very low	161 Å²	161	132.9 Å²	132.9	75%	0.745	79%	0.794	S	S	*	*			trans	-54.6	158.4	176.1	-42.5	-96.1	0	0	0	117.5
128	I	44.5	Very low	40.2	Very low	178 Å²	178	129.7 Å²	129.7	91%	0.913	79%	0.793	S	S	*	*				-166.4	160.2	120.3	41.4	171.3	0	0	0	111.4
129	S	39.2	Very low	40.2	Very low	125 Å²	125	131.7 Å²	131.7	87%	0.874	79%	0.793	S	S	*	*			trans	-107.3	150.9	-171.7	-55.7	0	0	0	0	114.4
130	G	39.2	Very low	40.2	Very low	70 Å²	70	138 Å²	138	72%	0.722	80%	0.802	S	S	*	*			trans	86.6	119.5	139.1	0	0	0	0	0	119.5
131	L	41.2	Very low	40.1	Very low	175 Å²	175	133.4 Å²	133.4	92%	0.916	79%	0.791	S	S	*	*				-177.6	161.4	122.1	-100.1	159.1	0	0	0	111.4
132	E	36.8	Very low	40	Very low	192 Å²	192	133.4 Å²	133.4	90%	0.897	79%	0.786	S	S	*	*			trans	-70.8	158.3	-177.5	-62.1	178	99.6	0	0	113.8
133	G	38	Very low	40	Very low	79 Å²	79	138 Å²	138	81%	0.814	79%	0.786	S	S	*	*			trans	141.7	112.3	149.7	0	0	0	0	0	116.9
134	G	38	Very low	40.3	Very low	76 Å²	76	143.6 Å²	143.6	78%	0.784	79%	0.791	S	S	*	*			trans	88.5	96.4	139.1	0	0	0	0	0	120
135	S	38.2	Very low	39.8	Very low	111 Å²	111	145 Å²	145	78%	0.776	79%	0.785	S	S	*	*				62.6	128.3	122.2	-139.2	0	0	0	0	122.8
136	V	38.8	Very low	40.4	Very low	131 Å²	131	144.8 Å²	144.8	79%	0.794	80%	0.795	S	S	*	*			trans	62.1	105.9	147.6	-65.5	0	0	0	0	123.2
137	S	37.4	Very low	40.2	Very low	122 Å²	122	144.1 Å²	144.1	85%	0.853	79%	0.785	S	S	*	*				92.6	149.5	120.8	-154.9	0	0	0	0	122.1
138	A	39.5	Very low	40.5	Very low	81 Å²	81	144 Å²	144	67%	0.669	79%	0.789	S	S	*	*			trans	99.4	101.9	153.3	0	0	0	0	0	122.4
139	R	40.3	Very low	40.3	Very low	213 Å²	213	142.2 Å²	142.2	80%	0.804	78%	0.78	S	S	*	*				61.3	130.7	127.4	-68.4	-170.8	174.7	-148.8	6	123.6	E141	R139-E141 IonicContact NH1-OE2 2.97Å
140	R	39.1	Very low	40.3	Very low	231 Å²	231	144 Å²	144	87%	0.872	78%	0.779	S	S	*	*				-175.9	131.9	103.5	-95.1	167.5	174.1	167.9	-0.2	108.8
141	E	38.6	Very low	40.3	Very low	144 Å²	144	146.2 Å²	146.2	67%	0.673	78%	0.781	S	S	*	*				72.3	134.2	65.6	-144.6	149.5	-161.8	0	0	111.3	R139	R139-E141 IonicContact NH1-OE2 2.97Å
142	V	39	Very low	40.1	Very low	106 Å²	106	145.8 Å²	145.8	64%	0.642	77%	0.774	S	S	*	*				-165.9	147.4	59.8	-170.1	0	0	0	0	111.3
143	Y	42.9	Very low	39.9	Very low	183 Å²	183	140 Å²	140	72%	0.718	76%	0.759	S	S	*	*				164.4	104.5	123.3	-98.9	-81.6	0	0	0	118.4
144	R	47.5	Very low	40	Very low	226 Å²	226	144.1 Å²	144.1	85%	0.853	76%	0.757	S	S	*	*			trans	70.4	153.4	145	-77.4	-177.9	-171	-179.4	5.5	123.1
145	R	35.1	Very low	39.8	Very low	194 Å²	194	144.1 Å²	144.1	73%	0.732	75%	0.749	S	S	*	*			trans	-158.2	151.1	-158.7	169.1	-175.8	-178.9	147.4	8.3	108.8	D147	R145-D147 IonicContact CZ-OD1 3.99Å; R145-D147 IonicContact CZ-OD2 2.86Å; R145-D147 VanDerWaalsContact CZ-OD2 3.24Å; R145-D147 IonicContact NE-OD1 3.71Å; R145-D147 IonicContact NE-OD2 3.24Å; R145-D147 PolarHBondContact NE-OD2 3.41Å; R145-D147 VanDerWaalsContact NH2-CG 3.31Å; R145-D147 IonicContact NH2-OD1 2.62Å; R145-D147 PolarHBondContact NH2-OD1 3.28Å; R145-D147 IonicContact NH2-OD2 3.14Å; R145-D147 PolarHBondContact NH2-OD2 3.3Å
146	S	52.3	Low	39.8	Very low	126 Å²	126	146.6 Å²	146.6	88%	0.881	75%	0.753	S	S	*	*			trans	-147.3	125.7	152.4	-75.7	0	0	0	0	109.6
147	D	39.8	Very low	39.7	Very low	102 Å²	102	149 Å²	149	55%	0.545	76%	0.756	S	S	.	*			trans	-82.8	160.8	171.1	-62.3	-92.9	0	0	0	111.5	R145	R145-D147 IonicContact CZ-OD1 3.99Å; R145-D147 IonicContact CZ-OD2 2.86Å; R145-D147 VanDerWaalsContact CZ-OD2 3.24Å; R145-D147 IonicContact NE-OD1 3.71Å; R145-D147 IonicContact NE-OD2 3.24Å; R145-D147 PolarHBondContact NE-OD2 3.41Å; R145-D147 VanDerWaalsContact NH2-CG 3.31Å; R145-D147 IonicContact NH2-OD1 2.62Å; R145-D147 PolarHBondContact NH2-OD1 3.28Å; R145-D147 IonicContact NH2-OD2 3.14Å; R145-D147 PolarHBondContact NH2-OD2 3.3Å
148	L	45.4	Very low	39.4	Very low	159 Å²	159	148 Å²	148	83%	0.832	76%	0.755	S	S	*	*				175.2	137.8	116.5	-96.9	162.7	0	0	0	115.7
149	L	40.4	Very low	39.3	Very low	141 Å²	141	147.5 Å²	147.5	74%	0.738	76%	0.757	S	S	*	*			trans	84.7	87.7	154.5	-58.4	176.8	0	0	0	123.4
150	L	38.5	Very low	39.2	Very low	161 Å²	161	145.6 Å²	145.6	84%	0.843	76%	0.762	S	S	*	*				62.7	155.7	121.1	-89.2	84.4	0	0	0	125
151	P	38.8	Very low	39.2	Very low	118 Å²	118	138.8 Å²	138.8	77%	0.766	76%	0.755	S	S	*	*			trans	-127.5	165.9	-163.7	43.9	-28.6	0	0	0	117.8
152	H	37.4	Very low	39.1	Very low	166 Å²	166	140.6 Å²	140.6	77%	0.769	76%	0.763	S	S	*	*			trans	-161.5	115.4	159.1	-150.8	70.5	0	0	0	107.3	H154	H152-H154 AromaticContact NE2-CD2 3.72Å; H152-H154 AromaticContact NE2-NE2 3.67Å
153	A	34.1	Very low	39.1	Very low	70 Å²	70	142.4 Å²	142.4	58%	0.579	77%	0.769	S	S	*	*				91.2	139.7	58.9	0	0	0	0	0	114
154	H	38.4	Very low	39	Very low	165 Å²	165	141.7 Å²	141.7	76%	0.764	78%	0.777	S	S	*	*			trans	76.9	151.5	175.9	-44.8	-74	0	0	0	118.1	H152	H152-H154 AromaticContact NE2-CD2 3.72Å; H152-H154 AromaticContact NE2-NE2 3.67Å
155	A	33.8	Very low	38.5	Very low	76 Å²	76	134.3 Å²	134.3	63%	0.628	77%	0.771	S	S	*	*			cis	-175.4	163	-33	0	0	0	0	0	108.9
156	L	39.3	Very low	38.5	Very low	164 Å²	164	133.4 Å²	133.4	86%	0.859	78%	0.78	S	S	*	*			trans	70.5	152.9	171.3	-47.9	173.1	0	0	0	114.7
157	E	35.6	Very low	37.9	Very low	182 Å²	182	136 Å²	136	85%	0.85	78%	0.778	S	S	*	*			cis	-148.8	164.9	11.7	-154.8	164.2	174.1	0	0	111.3
158	A	31.6	Very low	37.5	Very low	101 Å²	101	139.7 Å²	139.7	84%	0.835	79%	0.792	S	S	*	*			trans	-126.5	144.8	177.9	0	0	0	0	0	111.1
159	G	37.1	Very low	37.3	Very low	70 Å²	70	139.2 Å²	139.2	72%	0.722	79%	0.787	S	S	*	*			trans	178.9	153.4	173.5	0	0	0	0	0	114.7
160	L	39.7	Very low	36.9	Very low	173 Å²	173	136.9 Å²	136.9	91%	0.906	79%	0.788	S	S	*	*			trans	69.6	93.9	176.2	-53.6	171.5	0	0	0	113.9
161	A	38.1	Very low	36.9	Very low	87 Å²	87	136.9 Å²	136.9	72%	0.719	78%	0.784	S	S	*	*			cis	73.3	100.6	38.1	0	0	0	0	0	114.5
162	E	35.8	Very low	36.8	Very low	182 Å²	182	136.7 Å²	136.7	85%	0.85	78%	0.783	S	S	*	*			trans	26.4	121.2	142.1	-58.9	174.4	130.9	0	0	119.8
163	N	39.2	Very low	37.1	Very low	144 Å²	144	137 Å²	137	77%	0.77	79%	0.788	S	S	*	*				-169.5	135.6	128.3	-101.7	-51.7	0	0	0	112
164	L	40.3	Very low	37.3	Very low	168 Å²	168	142.9 Å²	142.9	88%	0.88	80%	0.804	S	S	*	*			trans	51	137.5	142.3	-49.9	166.8	0	0	0	118.9
165	G	37.9	Very low	37.2	Very low	71 Å²	71	143.7 Å²	143.7	73%	0.732	81%	0.808	S	S	*	*			cis	168.1	151.7	5.4	0	0	0	0	0	108.2	H167	G165-H167 PolarHBondContact O-N 3.26Å
166	L	34.9	Very low	37.7	Very low	176 Å²	176	146.8 Å²	146.8	92%	0.921	82%	0.818	S	S	*	*			trans	-63.5	130.9	-178.4	-73.4	149.6	0	0	0	111.5
167	H	40.8	Very low	37.6	Very low	179 Å²	179	147.5 Å²	147.5	83%	0.829	82%	0.818	S	S	*	*			trans	-147.6	110.2	147.7	-116.5	-71.5	0	0	0	112.2	G165	G165-H167 PolarHBondContact O-N 3.26Å
168	E	31.1	Very low	37.7	Very low	180 Å²	180	145 Å²	145	84%	0.841	81%	0.81	S	S	*	*			trans	-70.1	129.9	162.9	178.6	-174.8	141.7	0	0	109.2
169	M	39.7	Very low	38.5	Very low	149 Å²	149	145.6 Å²	145.6	73%	0.734	80%	0.803	S	S	*	*			trans	-154.3	115.9	162.3	-97.9	-59.7	-180	0	0	109.4
170	A	32.3	Very low	38.5	Very low	92 Å²	92	149.1 Å²	149.1	76%	0.76	81%	0.805	S	S	*	*			trans	-86.5	126.5	170.1	0	0	0	0	0	109.8
171	H	38.6	Very low	38.6	Very low	161 Å²	161	148.5 Å²	148.5	75%	0.745	80%	0.803	S	S	*	*			trans	-131.6	133.5	168.2	-75.3	-64.1	0	0	0	111.1
172	P	37.5	Very low	38.7	Very low	114 Å²	114	147.7 Å²	147.7	74%	0.74	80%	0.797	S	S	*	*			trans	-85.1	153.5	-178.3	35.1	-34.9	0	0	0	112.3	E174	P172-E174 PolarHBondContact O-N 3.06Å
173	I	42.3	Very low	38.8	Very low	173 Å²	173	147.6 Å²	147.6	89%	0.887	80%	0.795	S	S	*	*			trans	7.8	108.2	153.3	-53	171.7	0	0	0	115
174	E	38.5	Very low	38.8	Very low	194 Å²	194	149.1 Å²	149.1	91%	0.907	80%	0.803	S	S	*	*			trans	-108.4	150.7	163.9	-148.9	172.3	-161	0	0	111.1	P172	P172-E174 PolarHBondContact O-N 3.06Å
175	E	37.9	Very low	38.6	Very low	181 Å²	181	148.8 Å²	148.8	85%	0.846	80%	0.801	S	S	*	*	P	Polyproline II helix	trans	-92	158.5	-163.5	-164.6	165.9	-170.7	0	0	112.6	Q177	E175-Q177 PolarHBondContact O-N 3.27Å
176	V	44.7	Very low	38.9	Very low	141 Å²	141	152.5 Å²	152.5	86%	0.855	80%	0.803	S	S	*	*	P	Polyproline II helix	trans	-66.4	117.5	-172.2	175.5	0	0	0	0	111.7	N178	V176-N178 PolarHBondContact O-N 3.39Å
177	Q	36.5	Very low	39.2	Very low	180 Å²	180	151.3 Å²	151.3	84%	0.841	79%	0.793	S	S	*	*	P	Polyproline II helix	trans	-76.2	117.4	173.2	-144.1	169.1	20.2	0	0	110.4	E175	E175-Q177 PolarHBondContact O-N 3.27Å
178	N	36.9	Very low	39	Very low	128 Å²	128	149.4 Å²	149.4	68%	0.684	79%	0.789	S	S	*	*	P	Polyproline II helix	trans	-83.7	136.1	169.9	-173.8	56.8	0	0	0	109.4	V176 D180	V176-N178 PolarHBondContact O-N 3.39Å; N178-D180 PolarHBondContact ND2-OD2 3.45Å
179	V	48	Very low	39.8	Very low	115 Å²	115	147.8 Å²	147.8	70%	0.697	78%	0.781	S	S	*	*			trans	-117	104.1	174.6	-171.5	0	0	0	0	108
180	D	37.2	Very low	40.1	Very low	143 Å²	143	146.5 Å²	146.5	77%	0.765	78%	0.782	S	S	*	*			trans	-72.9	130.5	163.7	-85.1	-74.9	0	0	0	108.9	N178	N178-D180 PolarHBondContact ND2-OD2 3.45Å
181	D	41.9	Very low	40.6	Very low	160 Å²	160	148 Å²	148	86%	0.856	78%	0.782	S	S	*	*			trans	-121.4	130.9	170.1	-128.3	-34.9	0	0	0	109.6
182	A	40.7	Very low	41.1	Very low	71 Å²	71	147.2 Å²	147.2	59%	0.587	78%	0.781	S	S	*	*			trans	-109.8	170.2	-163.8	0	0	0	0	0	112.7
183	H	38	Very low	41.5	Very low	179 Å²	179	153.9 Å²	153.9	83%	0.829	79%	0.791	S	S	*	*			trans	70.5	111.8	170.5	-54.2	-84.8	0	0	0	117.5
184	L	40.2	Very low	41.5	Very low	177 Å²	177	155.4 Å²	155.4	93%	0.927	79%	0.792	S	S	*	*				-159.4	115.9	112.4	-104.1	163.6	0	0	0	109.7
185	L	35.3	Very low	41.5	Very low	160 Å²	160	149.7 Å²	149.7	84%	0.838	79%	0.785	S	S	*	*			trans	-119.2	106.6	-175.8	-167.2	-176.9	0	0	0	107.4
186	L	43.4	Very low	41.6	Very low	150 Å²	150	146.3 Å²	146.3	79%	0.785	78%	0.779	S	S	*	*			trans	-163.7	137.1	165.8	-116.7	159.2	0	0	0	115.2
187	H	42.3	Very low	41.7	Very low	150 Å²	150	147.2 Å²	147.2	69%	0.694	78%	0.777	S	S	*	*			trans	86.5	94.7	155.1	-112.6	72.9	0	0	0	120.7	Q189	H187-Q189 PolarHBondContact NE2-NE2 2.93Å
188	D	36.8	Very low	41.9	Very low	140 Å²	140	144.3 Å²	144.3	75%	0.749	78%	0.776	S	S	*	*			trans	-66.3	146.4	152.6	168	39.4	0	0	0	111.9
189	Q	46.3	Very low	42	Very low	146 Å²	146	146.6 Å²	146.6	68%	0.682	79%	0.785	S	S	*	*			trans	176.6	114.5	139.5	-102	171.8	94.3	0	0	111.3	H187	H187-Q189 PolarHBondContact NE2-NE2 2.93Å
190	T	47.3	Very low	41.9	Very low	122 Å²	122	148.2 Å²	148.2	75%	0.748	80%	0.795	S	S	*	*				166.1	104.3	114.3	39.7	0	0	0	0	115.7
191	V	41.6	Very low	42.1	Very low	124 Å²	124	151 Å²	151	75%	0.752	80%	0.801	S	S	*	*				45.2	96.1	129.7	-166.5	0	0	0	0	121
192	I	50.8	Low	42	Very low	144 Å²	144	151.1 Å²	151.1	74%	0.738	80%	0.801	S	S	*	*				41.2	119.8	119.7	-49	161.8	0	0	0	119.5
193	R	46	Very low	42	Very low	253 Å²	253	152.6 Å²	152.6	96%	0.955	81%	0.805	S	S	*	*				-164.2	161.3	115.3	-103.9	168.4	-166.7	153.3	6.7	113.3
194	K	41.7	Very low	42.5	Very low	206 Å²	206	152.6 Å²	152.6	90%	0.896	81%	0.81	S	S	*	*			trans	-132.2	138.1	-150.2	177.8	-174.7	-176.4	-179.8	0	110.9
195	G	39.1	Very low	42.1	Very low	73 Å²	73	147.3 Å²	147.3	75%	0.753	80%	0.799	S	S	*	*			trans	170.5	118	171.7	0	0	0	0	0	114.1
196	P	39.2	Very low	42.5	Very low	111 Å²	111	147.8 Å²	147.8	72%	0.721	80%	0.801	S	S	*	*			trans	-118.7	170.8	-178.3	43	-33.5	0	0	0	114.3
197	I	46.9	Very low	42.3	Very low	160 Å²	160	147 Å²	147	82%	0.821	81%	0.805	S	S	*	*			trans	74.6	115.5	164.6	-47.3	160	0	0	0	116.5
198	S	40.4	Very low	42	Very low	118 Å²	118	144.9 Å²	144.9	83%	0.825	81%	0.806	S	S	*	*				-175.9	159.1	101	-152.4	0	0	0	0	113
199	M	38.9	Very low	41.7	Very low	176 Å²	176	147 Å²	147	87%	0.867	81%	0.811	S	S	*	*			trans	-112.2	137	-177.8	-62.7	-150.3	-63.9	0	0	112.5
200	T	46.2	Very low	41.2	Very low	149 Å²	149	148.3 Å²	148.3	91%	0.914	82%	0.815	S	S	*	*			trans	-144.7	148.1	159.3	36.8	0	0	0	0	111.4
201	K	40.8	Very low	40.3	Very low	203 Å²	203	149.3 Å²	149.3	88%	0.883	82%	0.815	S	S	*	*			trans	-98	141.8	-176.3	-57.2	168.2	179.2	173	0	110.4
202	N	40.3	Very low	40.3	Very low	161 Å²	161	150.2 Å²	150.2	86%	0.861	82%	0.815	S	S	*	*				-164.4	157.9	124.6	-126.5	31.2	0	0	0	111.9
203	P	40.1	Very low	39.8	Very low	102 Å²	102	149.5 Å²	149.5	66%	0.662	82%	0.817	S	S	*	*			trans	-100.7	143.8	-169.8	37	-31	0	0	0	113.2
204	L	47.9	Very low	39.6	Very low	179 Å²	179	140.4 Å²	140.4	94%	0.937	80%	0.803	S	S	*	*			trans	-178.3	116.2	150.6	-103.6	156.3	0	0	0	111.2
205	G	33	Very low	40.4	Very low	67 Å²	67	135.4 Å²	135.4	69%	0.691	79%	0.789	S	S	*	*	S	Bend	trans	79.2	144.4	157.3	0	0	0	0	0	118.9
206	L	43.2	Very low	41.1	Very low	170 Å²	170	138.6 Å²	138.6	89%	0.89	79%	0.794	S	S	*	*			trans	69.8	109	163.7	-59.2	134.7	0	0	0	117.4	C208	L206-C208 PolarHBondContact O-N 3.44Å
207	P	40.3	Very low	43	Very low	132 Å²	132	135.5 Å²	135.5	86%	0.857	77%	0.77	S	S	*	*			trans	-74.5	97.5	168.2	30.9	-31.7	0	0	0	110.7
208	C	34.8	Very low	44.9	Very low	107 Å²	107	131.8 Å²	131.8	72%	0.723	75%	0.752	S	S	*	*			trans	37.1	104	135.7	-153.4	0	0	0	0	116.9	L206 K210	L206-C208 PolarHBondContact O-N 3.44Å; C208-K210 PolarHBondContact O-N 2.64Å; C208-K210 VanDerWaalsContact O-N 3.09Å
209	Q	31.9	Very low	47.3	Very low	183 Å²	183	128.6 Å²	128.6	86%	0.855	73%	0.728	S	S	*	*			trans	-42.7	116.5	142.1	-111.8	175.2	-20.2	0	0	108
210	K	34.9	Very low	49.7	Very low	175 Å²	175	122.7 Å²	122.7	76%	0.761	70%	0.704	S	S	*	*			trans	-102.5	105.2	171.4	-171.8	169.2	-175.1	176.3	0	107.7	C208 L212	C208-K210 PolarHBondContact O-N 2.64Å; C208-K210 VanDerWaalsContact O-N 3.09Å; K210-L212 PolarHBondContact O-N 3.45Å
211	D	29.1	Very low	52	Low	142 Å²	142	120.2 Å²	120.2	76%	0.759	68%	0.683	S	S	*	*			trans	-51.3	105.4	166.4	-62.4	-84.6	0	0	0	109.5
212	L	41.1	Very low	54.6	Low	144 Å²	144	113.3 Å²	113.3	75%	0.754	66%	0.657	S	S	*	*			trans	-108.9	84.5	160.7	-143.3	78.5	0	0	0	106.2	K210 G214	K210-L212 PolarHBondContact O-N 3.45Å; L212-G214 PolarHBondContact O-N 3.14Å
213	V	39.6	Very low	57.2	Low	128 Å²	128	106.2 Å²	106.2	78%	0.776	62%	0.619	S	S	*	*			trans	-43.9	117.1	168.1	174.7	0	0	0	0	107.2	V215	V213-V215 PolarHBondContact O-N 2.62Å
214	G	42.9	Very low	59.8	Low	63 Å²	63	102.8 Å²	102.8	65%	0.649	60%	0.597	S	S	*	*			trans	-57.9	110.8	-167.1	0	0	0	0	0	110.9	L212 V216	L212-G214 PolarHBondContact O-N 3.14Å; G214-V216 PolarHBondContact O-N 2.91Å
215	V	57.3	Low	62.1	Low	101 Å²	101	97.6 Å²	97.6	61%	0.612	58%	0.575	S	S	*	*			trans	-60.3	108.7	170.7	175.5	0	0	0	0	106.6	V213 M217	V213-V215 PolarHBondContact O-N 2.62Å; V215-M217 VanDerWaalsContact C-N 3.31Å; V215-M217 PolarHBondContact O-N 3.48Å
216	V	55.1	Low	65.1	Low	140 Å²	140	94.5 Å²	94.5	85%	0.848	54%	0.543	S	S	*	.			trans	-67.2	96.2	177.1	178.7	0	0	0	0	107.2	G214 N218	G214-V216 PolarHBondContact O-N 2.91Å; V216-N218 PolarHBondContact O-N 2.99Å
217	M	78	Confident	67.5	Low	45 Å²	45	89.1 Å²	89.1	22%	0.222	52%	0.518	C	S	.	.			trans	-60.2	116.1	177.8	179.6	-179.5	70.3	0	0	109.5	V215 P219 V243 Q247 I284 L286	V215-M217 VanDerWaalsContact C-N 3.31Å; V215-M217 PolarHBondContact O-N 3.48Å; M217-P219 WeakPolarHBondContact O-CD 3.48Å; M217-V243 HydrophobicContact CE-CG1 4.36Å; M217-V243 HydrophobicContact CG-CG1 3.36Å; M217-V243 HydrophobicContact SD-CG1 3.33Å; M217-V243 WeakPolarHBondContact SD-CG1 3.13Å; M217-Q247 VanDerWaalsContact CE-OE1 3.28Å; M217-I284 VanDerWaalsContact CG-O 3.3Å; M217-I284 WeakPolarHBondContact CG-O 3.36Å; M217-I284 VanDerWaalsContact SD-O 3.38Å; M217-L286 HydrophobicContact CE-CD2 4.13Å; M217-L286 HydrophobicContact SD-CD1 4.43Å; M217-L286 HydrophobicContact SD-CD2 3.49Å; M217-L286 WeakPolarHBondContact SD-CD2 3.44Å; M217-L286 HydrophobicContact SD-CG 3.74Å
218	N	87.8	Confident	70.1	Confident	83 Å²	83	83.4 Å²	83.4	44%	0.444	48%	0.483	S	S	.	.			trans	-76.7	110.3	173	-178.9	-7	0	0	0	109	V216 S220 E221	V216-N218 PolarHBondContact O-N 2.99Å; N218-S220 PolarHBondContact O-N 3.06Å; N218-S220 WeakPolarHBondContact OD1-CB 3.19Å; N218-S220 PolarHBondContact OD1-N 3.17Å; N218-S220 VanDerWaalsContact OD1-N 3.07Å; N218-E221 HydrophobicContact CB-CB 4.14Å; N218-E221 WeakPolarHBondContact O-CB 3.31Å; N218-E221 PolarHBondContact O-N 3.43Å; N218-E221 VanDerWaalsContact O-N 3.17Å
219	P	89.2	Confident	72.9	Confident	51 Å²	51	84.3 Å²	84.3	33%	0.331	47%	0.472	S	S	.	.	T	Hydrogen-bonded Turn	trans	-63.6	-25	-176.2	26.8	-35.1	0	0	0	113	M217 A244	M217-P219 WeakPolarHBondContact O-CD 3.48Å; P219-A244 HydrophobicContact CB-CB 4Å; P219-A244 WeakPolarHBondContact O-CB 3.48Å; P219-A244 PolarHBondContact O-N 3.03Å
220	S	90.7	Very high	75.7	Confident	52 Å²	52	81.2 Å²	81.2	36%	0.364	46%	0.46	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85.7	-8.9	-178.3	-59.1	0	0	0	0	113.6	N218	N218-S220 PolarHBondContact O-N 3.06Å; N218-S220 WeakPolarHBondContact OD1-CB 3.19Å; N218-S220 PolarHBondContact OD1-N 3.17Å; N218-S220 VanDerWaalsContact OD1-N 3.07Å
221	E	93.7	Very high	78.2	Confident	97 Å²	97	74.5 Å²	74.5	45%	0.453	44%	0.435	S	S	.	.	S	Bend	trans	-64	143.1	178.6	-171.9	-175.2	153.4	0	0	111.2	N218 F223 T242 V243	N218-E221 HydrophobicContact CB-CB 4.14Å; N218-E221 WeakPolarHBondContact O-CB 3.31Å; N218-E221 PolarHBondContact O-N 3.43Å; N218-E221 VanDerWaalsContact O-N 3.17Å; E221-F223 PolarHBondContact O-N 3.09Å; E221-T242 CarbonylContact O-C 3.54Å; E221-T242 WeakPolarHBondContact O-CA 3.48Å; E221-T242 WeakPolarHBondContact O-CB 3.49Å; E221-V243 HydrophobicContact CB-CG2 4.02Å; E221-V243 PolarHBondContact O-N 2.84Å
222	V	95.1	Very high	81.1	Confident	58 Å²	58	73.8 Å²	73.8	35%	0.352	43%	0.431	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-84.6	109.8	178.7	-178.4	0	0	0	0	109.9	K240 V241	V222-K240 HydrophobicContact CG1-CB 4.01Å; V222-K240 HydrophobicContact CG1-CG 4.18Å; V222-K240 HydrophobicContact CG2-CB 4.09Å; V222-K240 HydrophobicContact CG2-CD 3.99Å; V222-K240 HydrophobicContact CG2-CG 4.18Å; V222-V241 CarbonylContact C-O 3.59Å
223	F	95.2	Very high	83.1	Confident	11 Å²	11	75 Å²	75	5%	0.048	44%	0.437	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-69.7	-39.3	177.6	-178.1	-111.3	0	0	0	112.7	E221 V241 V243 V246 L265 L277 K280 L281 I284	E221-F223 PolarHBondContact O-N 3.09Å; F223-V241 PolarHBondContact N-O 3.3Å; F223-V243 HydrophobicContact CB-CG2 4.24Å; F223-V246 HydrophobicContact CB-CG2 4.09Å; F223-V246 HydrophobicContact CD1-CG2 3.8Å; F223-V246 HydrophobicContact CE1-CG2 4.49Å; F223-V246 HydrophobicContact CG-CG2 4.06Å; F223-L265 HydrophobicContact CD1-CD1 3.96Å; F223-L265 HydrophobicContact CE1-CD1 3.68Å; F223-L277 HydrophobicContact CE1-CD1 4.23Å; F223-L277 HydrophobicContact CZ-CD1 4.15Å; F223-K280 HydrophobicContact CE1-CD 4.4Å; F223-K280 HydrophobicContact CE2-CB 4.36Å; F223-K280 HydrophobicContact CE2-CD 3.72Å; F223-K280 HydrophobicContact CE2-CG 3.72Å; F223-K280 HydrophobicContact CZ-CB 4.18Å; F223-K280 HydrophobicContact CZ-CD 3.64Å; F223-K280 HydrophobicContact CZ-CG 3.88Å; F223-K280 PolarHBondContact O-NZ 3.06Å; F223-L281 HydrophobicContact CE1-CD2 4.24Å; F223-L281 HydrophobicContact CE2-CD2 4.02Å; F223-L281 HydrophobicContact CZ-CD2 3.65Å; F223-L281 HydrophobicContact CZ-CG 4.26Å; F223-I284 HydrophobicContact CD2-CD1 3.5Å; F223-I284 VanDerWaalsContact CD2-CD1 3.5Å; F223-I284 HydrophobicContact CE2-CD1 3.65Å; F223-I284 HydrophobicContact CE2-CG1 4.34Å; F223-I284 HydrophobicContact CG-CD1 4.44Å
224	C	95.9	Very high	85.3	Confident	31 Å²	31	74 Å²	74	21%	0.209	44%	0.436	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-164.6	160.9	168.8	59.3	0	0	0	0	111	V241	C224-V241 PolarHBondContact N-O 3.29Å; C224-V241 WeakPolarHBondContact O-CB 3.39Å; C224-V241 PolarHBondContact O-N 3.43Å
225	S	96.3	Very high	87.1	Confident	69 Å²	69	74.6 Å²	74.6	48%	0.483	43%	0.43	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-97.7	141	164.7	-64.4	0	0	0	0	109.9	Y239	S225-Y239 CarbonylContact C-O 3.59Å; S225-Y239 VanDerWaalsContact CA-O 3.31Å; S225-Y239 WeakPolarHBondContact CA-O 3.47Å
226	V	95.7	Very high	88.2	Confident	2 Å²	2	73.1 Å²	73.1	1%	0.012	42%	0.421	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.8	136.7	-174.4	-54.7	0	0	0	0	111.1	K238 Y239 V241 L265 R266 V305	V226-K238 CarbonylContact O-C 3.46Å; V226-K238 WeakPolarHBondContact O-CA 3.29Å; V226-Y239 PolarHBondContact N-O 3.47Å; V226-Y239 PolarHBondContact O-N 3.31Å; V226-V241 HydrophobicContact CG1-CG2 3.86Å; V226-V241 HydrophobicContact CG2-CG2 3.85Å; V226-L265 HydrophobicContact CG1-CD2 4.47Å; V226-R266 HydrophobicContact CB-CG 4.19Å; V226-R266 VanDerWaalsContact CG2-NE 3.32Å; V226-V305 HydrophobicContact CG2-CG1 4.04Å; V226-V305 HydrophobicContact CG2-CG2 3.85Å
227	P	93.8	Very high	89.7	Confident	57 Å²	57	68.8 Å²	68.8	37%	0.37	40%	0.397	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-71.5	137.1	179.1	28.4	-35.3	0	0	0	111.4	T236 R266	P227-T236 HydrophobicContact CB-CG2 4.04Å; P227-R266 WeakPolarHBondContact O-CD 3.33Å; P227-R266 PolarHBondContact O-NE 3.41Å; P227-R266 PolarHBondContact O-NH1 2.7Å
228	G	93.8	Very high	90.4	Very high	12 Å²	12	74.4 Å²	74.4	12%	0.124	42%	0.42	C	S	.	.			trans	-51.9	147.6	180	0	0	0	0	0	114.6	S237 E308	G228-S237 PolarHBondContact N-O 3.41Å; G228-E308 VanDerWaalsContact CA-OE1 3.28Å; G228-E308 WeakPolarHBondContact CA-OE1 3.4Å
229	R	93.7	Very high	90.8	Very high	127 Å²	127	72 Å²	72	48%	0.479	41%	0.405	S	S	.	.	S	Bend	trans	-91.7	-32.3	173.5	-71.9	-28.6	-168.6	-174.8	8.8	113.1	E308	R229-E308 PolarHBondContact N-OE1 2.87Å
230	L	91.8	Very high	91.1	Very high	118 Å²	118	76.7 Å²	76.7	62%	0.618	42%	0.42	S	S	*	.	S	Bend	trans	-96.7	0.9	178.7	-55.7	-179.8	0	0	0	112.6	L304 L312	L230-L304 HydrophobicContact CD1-CD2 4.23Å; L230-L304 HydrophobicContact CG-CD2 4.37Å; L230-L312 HydrophobicContact CD1-CD1 4Å; L230-L312 HydrophobicContact CD1-CD2 3.96Å; L230-L312 HydrophobicContact CD1-CG 4.44Å
231	S	87.4	Confident	91.4	Very high	33 Å²	33	74.2 Å²	74.2	23%	0.231	40%	0.403	C	S	.	.	S	Bend	trans	-78.7	136	176.8	-61.5	0	0	0	0	111.7	S235	S231-S235 WeakPolarHBondContact CB-O 3.41Å
232	L	88.1	Confident	91.5	Very high	127 Å²	127	70.3 Å²	70.3	67%	0.665	39%	0.386	S	S	*	.			trans	-64.3	150.8	164.6	-63.1	177.9	0	0	0	110.2	S234 S235 T236	L232-S234 PolarHBondContact O-N 3.28Å; L232-S235 CarbonylContact O-C 3.26Å; L232-S235 VanDerWaalsContact O-C 3.26Å; L232-S235 WeakPolarHBondContact O-CA 3.39Å; L232-S235 PolarHBondContact O-N 3.29Å; L232-T236 PolarHBondContact O-N 3.39Å
233	L	84.2	Confident	91.5	Very high	171 Å²	171	67.5 Å²	67.5	90%	0.895	37%	0.369	S	S	*	.	G	3₁₀ helix	trans	-54.9	-40.2	-178.9	-67.2	173.6	0	0	0	112.6	S235 T236	L233-S235 PolarHBondContact O-N 3.2Å; L233-T236 PolarHBondContact O-OG1 3Å
234	S	85.4	Confident	91.4	Very high	106 Å²	106	67 Å²	67	74%	0.741	37%	0.367	S	S	*	.	G	3₁₀ helix	trans	-65.7	-21.2	176	55.4	0	0	0	0	114.6	L232	L232-S234 PolarHBondContact O-N 3.28Å
235	S	81.7	Confident	91.5	Very high	75 Å²	75	65.7 Å²	65.7	52%	0.524	36%	0.358	S	S	.	.	G	3₁₀ helix	trans	-129.3	42.8	-170.1	-49.3	0	0	0	0	110.5	S231 L232 L233 S237	S231-S235 WeakPolarHBondContact CB-O 3.41Å; L232-S235 CarbonylContact O-C 3.26Å; L232-S235 VanDerWaalsContact O-C 3.26Å; L232-S235 WeakPolarHBondContact O-CA 3.39Å; L232-S235 PolarHBondContact O-N 3.29Å; L233-S235 PolarHBondContact O-N 3.2Å; S235-S237 PolarHBondContact O-N 2.93Å
236	T	79.3	Confident	91.4	Very high	70 Å²	70	62.4 Å²	62.4	43%	0.429	34%	0.335	S	S	.	.			trans	-72.2	97	-174.9	-61.5	0	0	0	0	111.5	P227 L232 L233	P227-T236 HydrophobicContact CB-CG2 4.04Å; L232-T236 PolarHBondContact O-N 3.39Å; L233-T236 PolarHBondContact O-OG1 3Å
237	S	86.4	Confident	91.4	Very high	49 Å²	49	66.3 Å²	66.3	34%	0.343	35%	0.353	S	S	.	.	P	Polyproline II helix	trans	-71.1	136.8	168.1	-51.2	0	0	0	0	110.8	G228 S235	G228-S237 PolarHBondContact N-O 3.41Å; S235-S237 PolarHBondContact O-N 2.93Å
238	K	93.2	Very high	91.4	Very high	163 Å²	163	64.7 Å²	64.7	71%	0.709	34%	0.339	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-98.1	120.9	168.4	-68.5	179.6	-177.4	174.2	0	109	V226	V226-K238 CarbonylContact O-C 3.46Å; V226-K238 WeakPolarHBondContact O-CA 3.29Å
239	Y	95.4	Very high	91.5	Very high	32 Å²	32	64.3 Å²	64.3	13%	0.125	33%	0.334	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-96	129.1	179.6	-65.8	-88.9	0	0	0	110.5	S225 V226 V305 G307 E308 H311	S225-Y239 CarbonylContact C-O 3.59Å; S225-Y239 VanDerWaalsContact CA-O 3.31Å; S225-Y239 WeakPolarHBondContact CA-O 3.47Å; V226-Y239 PolarHBondContact N-O 3.47Å; V226-Y239 PolarHBondContact O-N 3.31Å; Y239-V305 HydrophobicContact CG-CG2 4.27Å; Y239-G307 VanDerWaalsContact CD1-C 3.43Å; Y239-G307 WeakPolarHBondContact CE1-O 3.45Å; Y239-E308 HydrophobicContact CD1-CG 4.01Å; Y239-E308 HydrophobicContact CD2-CG 3.5Å; Y239-E308 HydrophobicContact CE1-CG 3.96Å; Y239-E308 HydrophobicContact CE2-CG 3.46Å; Y239-E308 VanDerWaalsContact CE2-CG 3.46Å; Y239-E308 HydrophobicContact CG-CG 3.78Å; Y239-H311 HydrophobicContact CE1-CB 4.34Å; Y239-H311 AromaticContact CE1-ND1 4Å; Y239-H311 AromaticContact CZ-ND1 3.88Å; Y239-H311 PolarHBondContact OH-ND1 2.92Å
240	K	95.9	Very high	91.5	Very high	150 Å²	150	58.8 Å²	58.8	65%	0.652	31%	0.314	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-74.6	123.1	173.8	-68.4	174.6	176.3	179.4	0	108.9	V222	V222-K240 HydrophobicContact CG1-CB 4.01Å; V222-K240 HydrophobicContact CG1-CG 4.18Å; V222-K240 HydrophobicContact CG2-CB 4.09Å; V222-K240 HydrophobicContact CG2-CD 3.99Å; V222-K240 HydrophobicContact CG2-CG 4.18Å
241	V	96.7	Very high	91.5	Very high	1 Å²	1	55.3 Å²	55.3	1%	0.006	30%	0.3	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-100.4	118.9	171.3	179.5	0	0	0	0	108	V222 F223 C224 V226 E245 V246 L265 V305	V222-V241 CarbonylContact C-O 3.59Å; F223-V241 PolarHBondContact N-O 3.3Å; C224-V241 PolarHBondContact N-O 3.29Å; C224-V241 WeakPolarHBondContact O-CB 3.39Å; C224-V241 PolarHBondContact O-N 3.43Å; V226-V241 HydrophobicContact CG1-CG2 3.86Å; V226-V241 HydrophobicContact CG2-CG2 3.85Å; V241-E245 HydrophobicContact CG1-CB 4.19Å; V241-E245 HydrophobicContact CG1-CG 4.09Å; V241-V246 HydrophobicContact CG1-CG2 3.83Å; V241-L265 HydrophobicContact CB-CD2 4.22Å; V241-L265 HydrophobicContact CG1-CD2 3.77Å; V241-L265 HydrophobicContact CG2-CD2 4.02Å; V241-V305 HydrophobicContact CG2-CB 4.06Å; V241-V305 HydrophobicContact CG2-CG1 3.56Å; V241-V305 HydrophobicContact CG2-CG2 4.38Å
242	T	95.7	Very high	91.8	Very high	14 Å²	14	58.3 Å²	58.3	9%	0.086	32%	0.318	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-87.2	160.9	-178.6	63.3	0	0	0	0	112.3	E221 A244 E245 V246	E221-T242 CarbonylContact O-C 3.54Å; E221-T242 WeakPolarHBondContact O-CA 3.48Å; E221-T242 WeakPolarHBondContact O-CB 3.49Å; T242-A244 PolarHBondContact O-N 3.37Å; T242-E245 PolarHBondContact O-N 3.04Å; T242-E245 VanDerWaalsContact O-N 3.09Å; T242-E245 PolarHBondContact OG1-N 2.92Å; T242-V246 PolarHBondContact O-N 3.48Å; T242-V246 VanDerWaalsContact O-N 3.08Å
243	V	95	Very high	92.1	Very high	0 Å²	0	53.1 Å²	53.1	0%	0	29%	0.292	C	S	.	.	H	α-helix	trans	-58	-37.3	173.6	173	0	0	0	0	111.1	M217 E221 F223 V246 Q247 I284 L286	M217-V243 HydrophobicContact CE-CG1 4.36Å; M217-V243 HydrophobicContact CG-CG1 3.36Å; M217-V243 HydrophobicContact SD-CG1 3.33Å; M217-V243 WeakPolarHBondContact SD-CG1 3.13Å; E221-V243 HydrophobicContact CB-CG2 4.02Å; E221-V243 PolarHBondContact O-N 2.84Å; F223-V243 HydrophobicContact CB-CG2 4.24Å; V243-V246 PolarHBondContact O-N 3.39Å; V243-Q247 WeakPolarHBondContact O-CB 3.37Å; V243-Q247 PolarHBondContact O-N 3Å; V243-I284 HydrophobicContact CB-CD1 4.45Å; V243-I284 HydrophobicContact CG1-CD1 3.94Å; V243-I284 HydrophobicContact CG2-CD1 3.85Å; V243-L286 HydrophobicContact CG1-CD1 4.25Å
244	A	94.6	Very high	92.5	Very high	0 Å²	0	45.2 Å²	45.2	0%	0	25%	0.251	C	S	.	.	H	α-helix	trans	-59.1	-43.3	171.6	0	0	0	0	0	113.7	P219 T242 Q247 R248	P219-A244 HydrophobicContact CB-CB 4Å; P219-A244 WeakPolarHBondContact O-CB 3.48Å; P219-A244 PolarHBondContact O-N 3.03Å; T242-A244 PolarHBondContact O-N 3.37Å; A244-Q247 PolarHBondContact O-N 3.19Å; A244-R248 WeakPolarHBondContact O-CG 3.42Å; A244-R248 PolarHBondContact O-N 3.34Å
245	E	96.4	Very high	93	Very high	4 Å²	4	41.1 Å²	41.1	2%	0.019	22%	0.222	C	C	.	.	H	α-helix	trans	-61.7	-49.6	175.4	172.4	167.6	-162.7	0	0	109.8	V241 T242 Q247 R248 R249 V305 E306	V241-E245 HydrophobicContact CG1-CB 4.19Å; V241-E245 HydrophobicContact CG1-CG 4.09Å; T242-E245 PolarHBondContact O-N 3.04Å; T242-E245 VanDerWaalsContact O-N 3.09Å; T242-E245 PolarHBondContact OG1-N 2.92Å; E245-Q247 VanDerWaalsContact C-N 3.26Å; E245-Q247 PolarHBondContact O-N 3.24Å; E245-R248 PolarHBondContact O-N 2.91Å; E245-R248 VanDerWaalsContact O-N 3.08Å; E245-R249 HydrophobicContact CG-CG 4.3Å; E245-R249 WeakPolarHBondContact O-CG 3.31Å; E245-R249 PolarHBondContact O-N 2.96Å; E245-R249 IonicContact OE1-CZ 3.97Å; E245-R249 IonicContact OE1-NE 2.7Å; E245-R249 PolarHBondContact OE1-NE 2.86Å; E245-R249 IonicContact OE1-NH2 3.31Å; E245-R249 PolarHBondContact OE1-NH2 2.86Å; E245-V305 VanDerWaalsContact OE1-CA 3.28Å; E245-V305 WeakPolarHBondContact OE1-CA 3.38Å; E245-V305 WeakPolarHBondContact OE1-CB 3.48Å; E245-E306 HydrophobicContact CG-CG 4.23Å; E245-E306 WeakPolarHBondContact CG-OE1 3.36Å; E245-E306 PolarHBondContact OE1-N 3.28Å
246	V	95.9	Very high	93.6	Very high	0 Å²	0	37.7 Å²	37.7	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-57.4	-41.8	178.2	-178	0	0	0	0	111.2	F223 V241 T242 V243 R249 L250 L261 L281 L286	F223-V246 HydrophobicContact CB-CG2 4.09Å; F223-V246 HydrophobicContact CD1-CG2 3.8Å; F223-V246 HydrophobicContact CE1-CG2 4.49Å; F223-V246 HydrophobicContact CG-CG2 4.06Å; V241-V246 HydrophobicContact CG1-CG2 3.83Å; T242-V246 PolarHBondContact O-N 3.48Å; T242-V246 VanDerWaalsContact O-N 3.08Å; V243-V246 PolarHBondContact O-N 3.39Å; V246-R249 PolarHBondContact O-N 2.97Å; V246-L250 HydrophobicContact CG1-CD1 4.23Å; V246-L250 VanDerWaalsContact O-CG 3.3Å; V246-L250 WeakPolarHBondContact O-CG 3.3Å; V246-L250 PolarHBondContact O-N 3.46Å; V246-L250 VanDerWaalsContact O-N 3.14Å; V246-L261 HydrophobicContact CG1-CD2 4.03Å; V246-L281 HydrophobicContact CG1-CD2 3.49Å; V246-L281 VanDerWaalsContact CG1-CD2 3.49Å; V246-L286 HydrophobicContact CB-CD1 3.99Å; V246-L286 HydrophobicContact CG1-CD1 3.69Å
247	Q	94.3	Very high	94.2	Very high	83 Å²	83	36.5 Å²	36.5	39%	0.388	19%	0.189	S	C	.	.	H	α-helix	trans	-59.4	-47.9	175.3	-169.5	178.9	17.7	0	0	111.7	M217 V243 A244 E245 R249 L250 S251 L286	M217-Q247 VanDerWaalsContact CE-OE1 3.28Å; V243-Q247 WeakPolarHBondContact O-CB 3.37Å; V243-Q247 PolarHBondContact O-N 3Å; A244-Q247 PolarHBondContact O-N 3.19Å; E245-Q247 VanDerWaalsContact C-N 3.26Å; E245-Q247 PolarHBondContact O-N 3.24Å; Q247-R249 VanDerWaalsContact C-N 3.34Å; Q247-R249 PolarHBondContact O-N 3.45Å; Q247-L250 PolarHBondContact O-N 2.85Å; Q247-L250 VanDerWaalsContact O-N 3.09Å; Q247-S251 PolarHBondContact O-N 2.98Å; Q247-S251 PolarHBondContact O-OG 3.35Å; Q247-L286 HydrophobicContact CB-CD1 4.33Å; Q247-L286 HydrophobicContact CB-CD2 3.98Å; Q247-L286 HydrophobicContact CG-CD2 3.89Å
248	R	94.8	Very high	94.5	Very high	24 Å²	24	35 Å²	35	9%	0.091	18%	0.179	C	C	.	.	H	α-helix	trans	-60.3	-39.1	176.8	-73.2	-178.7	-63.8	-108.2	-6.6	112.7	A244 E245 L250 S251 E306 P371 G373 L394	A244-R248 WeakPolarHBondContact O-CG 3.42Å; A244-R248 PolarHBondContact O-N 3.34Å; E245-R248 PolarHBondContact O-N 2.91Å; E245-R248 VanDerWaalsContact O-N 3.08Å; R248-L250 VanDerWaalsContact C-N 3.27Å; R248-L250 PolarHBondContact O-N 3.14Å; R248-S251 WeakPolarHBondContact CA-OG 3.27Å; R248-S251 PolarHBondContact O-OG 3.39Å; R248-E306 IonicContact CZ-OE1 2Å; R248-E306 IonicContact CZ-OE2 3.3Å; R248-E306 IonicContact NE-OE1 3.69Å; R248-E306 PolarHBondContact NE-OE1 2.82Å; R248-E306 IonicContact NE-OE2 2.74Å; R248-E306 IonicContact NH2-OE1 3.85Å; R248-E306 PolarHBondContact NH2-OE1 2.74Å; R248-E306 IonicContact NH2-OE2 3.32Å; R248-E306 PolarHBondContact NH2-OE2 3.34Å; R248-P371 WeakPolarHBondContact CD-O 3.34Å; R248-P371 VanDerWaalsContact CZ-O 3.26Å; R248-P371 PolarHBondContact NE-O 3.07Å; R248-P371 PolarHBondContact NH1-O 2.99Å; R248-G373 PolarHBondContact NH1-O 2.95Å; R248-G373 PolarHBondContact NH2-O 2.66Å; R248-L394 HydrophobicContact CB-CD2 4.24Å; R248-L394 HydrophobicContact CG-CD2 4.07Å
249	R	95.1	Very high	94.3	Very high	4 Å²	4	31.9 Å²	31.9	2%	0.015	18%	0.178	C	C	.	.	H	α-helix	trans	-64.7	-29.4	174.7	-61.8	-49.2	179.5	125.4	5.1	113.2	E245 V246 Q247 E254 L256 L261 T302 L304 H397	E245-R249 HydrophobicContact CG-CG 4.3Å; E245-R249 WeakPolarHBondContact O-CG 3.31Å; E245-R249 PolarHBondContact O-N 2.96Å; E245-R249 IonicContact OE1-CZ 3.97Å; E245-R249 IonicContact OE1-NE 2.7Å; E245-R249 PolarHBondContact OE1-NE 2.86Å; E245-R249 IonicContact OE1-NH2 3.31Å; E245-R249 PolarHBondContact OE1-NH2 2.86Å; V246-R249 PolarHBondContact O-N 2.97Å; Q247-R249 VanDerWaalsContact C-N 3.34Å; Q247-R249 PolarHBondContact O-N 3.45Å; R249-E254 WeakPolarHBondContact CD-OE2 3.45Å; R249-E254 IonicContact CZ-OE2 3.5Å; R249-E254 IonicContact NE-OE2 3.15Å; R249-E254 IonicContact NH1-OE2 2.64Å; R249-E254 PolarHBondContact NH1-OE2 2.75Å; R249-L256 HydrophobicContact CB-CD1 4.04Å; R249-L256 HydrophobicContact CB-CG 4.33Å; R249-L256 HydrophobicContact CG-CD1 4.37Å; R249-L256 WeakPolarHBondContact O-CB 3.19Å; R249-L256 WeakPolarHBondContact O-CG 3.38Å; R249-L256 PolarHBondContact O-N 2.81Å; R249-L261 HydrophobicContact CB-CD1 4.32Å; R249-T302 PolarHBondContact NH1-O 3.41Å; R249-L304 PolarHBondContact NH1-O 3.3Å; R249-L304 PolarHBondContact NH2-O 2.94Å; R249-H397 PolarHBondContact NH1-CD2 3.06Å; R249-H397 VanDerWaalsContact NH1-CD2 3.3Å; R249-H397 PolarHBondContact NH1-NE2 2.97Å; R249-H397 PolarHBondContact NH2-CD2 3Å; R249-H397 VanDerWaalsContact NH2-CD2 3.32Å
250	L	94.2	Very high	94.2	Very high	10 Å²	10	32.6 Å²	32.6	5%	0.052	18%	0.184	C	C	.	.	H	α-helix	trans	-89.7	-20.7	-177.4	-68.1	-174.6	0	0	0	113.9	V246 Q247 R248 L256 L261 L281 L286 L288 R292	V246-L250 HydrophobicContact CG1-CD1 4.23Å; V246-L250 VanDerWaalsContact O-CG 3.3Å; V246-L250 WeakPolarHBondContact O-CG 3.3Å; V246-L250 PolarHBondContact O-N 3.46Å; V246-L250 VanDerWaalsContact O-N 3.14Å; Q247-L250 PolarHBondContact O-N 2.85Å; Q247-L250 VanDerWaalsContact O-N 3.09Å; R248-L250 VanDerWaalsContact C-N 3.27Å; R248-L250 PolarHBondContact O-N 3.14Å; L250-L256 VanDerWaalsContact CD2-O 3.31Å; L250-L256 WeakPolarHBondContact CD2-O 3.36Å; L250-L261 HydrophobicContact CD1-CD2 4.45Å; L250-L261 HydrophobicContact CD2-CD2 3.77Å; L250-L261 HydrophobicContact CG-CD2 4.24Å; L250-L281 HydrophobicContact CD1-CD1 4.14Å; L250-L286 HydrophobicContact CD1-CB 4.44Å; L250-L288 HydrophobicContact CD1-CB 4.33Å; L250-L288 HydrophobicContact CD2-CD1 3.78Å; L250-L288 HydrophobicContact CD2-CD2 3.95Å; L250-L288 HydrophobicContact CD2-CG 4.31Å; L250-R292 PolarHBondContact O-NH1 3.11Å
251	S	93	Very high	94.2	Very high	46 Å²	46	25.5 Å²	25.5	32%	0.322	15%	0.153	S	C	.	.	S	Bend	trans	-86.5	173.2	171.3	61.5	0	0	0	0	112.1	Q247 R248 E254 C255	Q247-S251 PolarHBondContact O-N 2.98Å; Q247-S251 PolarHBondContact O-OG 3.35Å; R248-S251 WeakPolarHBondContact CA-OG 3.27Å; R248-S251 PolarHBondContact O-OG 3.39Å; S251-E254 PolarHBondContact O-N 3.02Å; S251-C255 VanDerWaalsContact C-SG 3.57Å; S251-C255 WeakPolarHBondContact O-CA 3.45Å; S251-C255 PolarHBondContact O-N 3.01Å
252	P	92.4	Very high	94.1	Very high	95 Å²	95	26 Å²	26	62%	0.617	16%	0.158	S	C	*	.	T	Hydrogen-bonded Turn	trans	-55.5	151	162.9	-24.5	35.5	0	0	0	111.3	C255	P252-C255 VanDerWaalsContact N-SG 3.4Å
253	P	94.2	Very high	94.1	Very high	19 Å²	19	27.5 Å²	27.5	12%	0.123	18%	0.176	C	C	.	.	T	Hydrogen-bonded Turn	cis	-82.2	-20.1	4.2	32.4	-35.8	0	0	0	114.9	A295 L394 I395	P253-A295 WeakPolarHBondContact O-CB 3.32Å; P253-L394 HydrophobicContact CG-CB 3.95Å; P253-I395 HydrophobicContact CB-CD1 4.13Å; P253-I395 HydrophobicContact CG-CB 4.46Å; P253-I395 HydrophobicContact CG-CD1 3.84Å
254	E	93.9	Very high	94.1	Very high	4 Å²	4	27.8 Å²	27.8	2%	0.019	18%	0.178	C	C	.	.	T	Hydrogen-bonded Turn	trans	-77.3	-44.1	-171.6	-68.9	-163.9	103.1	0	0	113.8	R249 S251 L256 A295 T302 I395 H397	R249-E254 WeakPolarHBondContact CD-OE2 3.45Å; R249-E254 IonicContact CZ-OE2 3.5Å; R249-E254 IonicContact NE-OE2 3.15Å; R249-E254 IonicContact NH1-OE2 2.64Å; R249-E254 PolarHBondContact NH1-OE2 2.75Å; S251-E254 PolarHBondContact O-N 3.02Å; E254-L256 VanDerWaalsContact C-N 3.29Å; E254-L256 HydrophobicContact CB-CD2 3.87Å; E254-L256 HydrophobicContact CB-CG 3.94Å; E254-L256 PolarHBondContact O-N 2.97Å; E254-A295 PolarHBondContact O-N 2.78Å; E254-T302 WeakPolarHBondContact OE1-CG2 3.44Å; E254-T302 PolarHBondContact OE1-OG1 3.47Å; E254-I395 HydrophobicContact CG-CD1 3.7Å; E254-H397 IonicContact OE1-CE1 3.66Å; E254-H397 PolarHBondContact OE1-CE1 3.45Å; E254-H397 VanDerWaalsContact OE1-CE1 3.3Å; E254-H397 IonicContact OE1-NE2 2.83Å; E254-H397 PolarHBondContact OE1-NE2 2.9Å; E254-H397 IonicContact OE2-CD2 2.72Å; E254-H397 IonicContact OE2-NE2 3.76Å; E254-H397 PolarHBondContact OE2-NE2 3.3Å
255	C	94.1	Very high	94.2	Very high	21 Å²	21	28.2 Å²	28.2	14%	0.142	18%	0.18	C	C	.	.			trans	48.7	46	-173.2	-66	0	0	0	0	112.9	S251 P252 N257 A295	S251-C255 VanDerWaalsContact C-SG 3.57Å; S251-C255 WeakPolarHBondContact O-CA 3.45Å; S251-C255 PolarHBondContact O-N 3.01Å; P252-C255 VanDerWaalsContact N-SG 3.4Å; C255-N257 PolarHBondContact O-N 3.22Å; C255-A295 HydrophobicContact CB-CB 3.71Å
256	L	94.7	Very high	94.1	Very high	3 Å²	3	29.5 Å²	29.5	2%	0.016	19%	0.185	C	C	.	.			trans	-56.9	139.1	-173.1	-63.7	-168.1	0	0	0	112.1	R249 L250 E254 L260 L261 V264 T302	R249-L256 HydrophobicContact CB-CD1 4.04Å; R249-L256 HydrophobicContact CB-CG 4.33Å; R249-L256 HydrophobicContact CG-CD1 4.37Å; R249-L256 WeakPolarHBondContact O-CB 3.19Å; R249-L256 WeakPolarHBondContact O-CG 3.38Å; R249-L256 PolarHBondContact O-N 2.81Å; L250-L256 VanDerWaalsContact CD2-O 3.31Å; L250-L256 WeakPolarHBondContact CD2-O 3.36Å; E254-L256 VanDerWaalsContact C-N 3.29Å; E254-L256 HydrophobicContact CB-CD2 3.87Å; E254-L256 HydrophobicContact CB-CG 3.94Å; E254-L256 PolarHBondContact O-N 2.97Å; L256-L260 HydrophobicContact CB-CB 4.34Å; L256-L260 HydrophobicContact CD2-CB 4.14Å; L256-L260 HydrophobicContact CD2-CD1 4.09Å; L256-L261 HydrophobicContact CB-CB 4.47Å; L256-V264 HydrophobicContact CD1-CG2 4.15Å; L256-T302 HydrophobicContact CD2-CG2 4.22Å
257	N	92.3	Very high	94	Very high	44 Å²	44	33.7 Å²	33.7	24%	0.235	20%	0.201	C	C	.	.			trans	-85	167.9	172.1	72.3	36.4	0	0	0	111.4	C255 S259 L260 L261 R292	C255-N257 PolarHBondContact O-N 3.22Å; N257-S259 PolarHBondContact O-N 3.12Å; N257-S259 WeakPolarHBondContact OD1-CA 3.44Å; N257-S259 WeakPolarHBondContact OD1-CB 3.4Å; N257-S259 PolarHBondContact OD1-N 3.49Å; N257-L260 PolarHBondContact O-N 3.06Å; N257-L260 VanDerWaalsContact O-N 3.16Å; N257-L260 PolarHBondContact OD1-N 3.44Å; N257-L261 WeakPolarHBondContact O-CB 3.36Å; N257-L261 PolarHBondContact O-N 3.26Å; N257-R292 VanDerWaalsContact CB-O 3.29Å; N257-R292 WeakPolarHBondContact CB-O 3.35Å
258	A	92.2	Very high	93.7	Very high	17 Å²	17	34.1 Å²	34.1	14%	0.14	22%	0.219	C	C	.	.	T	Hydrogen-bonded Turn	trans	-59.1	-22.8	-177	0	0	0	0	0	115	G262 L277 L288	A258-G262 PolarHBondContact O-N 3.31Å; A258-G262 VanDerWaalsContact O-N 3.11Å; A258-L277 HydrophobicContact CB-CD2 4.11Å; A258-L288 HydrophobicContact CB-CD2 3.72Å; A258-L288 HydrophobicContact CB-CG 4.34Å
259	S	90.3	Very high	93.4	Very high	99 Å²	99	43.6 Å²	43.6	69%	0.692	26%	0.26	S	S	*	.	T	Hydrogen-bonded Turn	trans	-79.1	-47.5	176.6	-166.3	0	0	0	0	111.2	N257 G262 G263	N257-S259 PolarHBondContact O-N 3.12Å; N257-S259 WeakPolarHBondContact OD1-CA 3.44Å; N257-S259 WeakPolarHBondContact OD1-CB 3.4Å; N257-S259 PolarHBondContact OD1-N 3.49Å; S259-G262 CarbonylContact O-C 3.57Å; S259-G262 VanDerWaalsContact O-CA 3.28Å; S259-G262 WeakPolarHBondContact O-CA 3.38Å; S259-G262 PolarHBondContact O-N 3.38Å; S259-G263 PolarHBondContact O-N 3.32Å
260	L	93.7	Very high	93.1	Very high	47 Å²	47	46.7 Å²	46.7	25%	0.246	28%	0.283	C	S	.	.	H	α-helix	trans	-65.2	-48.1	177.5	-68.8	170.8	0	0	0	111.3	L256 N257 G262 G263 V264 K294 V298	L256-L260 HydrophobicContact CB-CB 4.34Å; L256-L260 HydrophobicContact CD2-CB 4.14Å; L256-L260 HydrophobicContact CD2-CD1 4.09Å; N257-L260 PolarHBondContact O-N 3.06Å; N257-L260 VanDerWaalsContact O-N 3.16Å; N257-L260 PolarHBondContact OD1-N 3.44Å; L260-G262 PolarHBondContact O-N 2.94Å; L260-G263 WeakPolarHBondContact O-CA 3.36Å; L260-G263 PolarHBondContact O-N 3.42Å; L260-V264 WeakPolarHBondContact O-CG2 3.33Å; L260-V264 PolarHBondContact O-N 2.85Å; L260-K294 HydrophobicContact CD1-CB 3.97Å; L260-K294 HydrophobicContact CD1-CD 3.73Å; L260-K294 HydrophobicContact CD1-CG 4.46Å; L260-V298 HydrophobicContact CD1-CG2 4.05Å; L260-V298 HydrophobicContact CD2-CG2 4.21Å
261	L	95.1	Very high	92.9	Very high	1 Å²	1	56.2 Å²	56.2	1%	0.005	32%	0.324	C	S	.	.	H	α-helix	trans	-61.7	-25.4	171.5	-174.7	62.6	0	0	0	111.7	V246 R249 L250 L256 N257 L265 R267 L277 L281 L288	V246-L261 HydrophobicContact CG1-CD2 4.03Å; R249-L261 HydrophobicContact CB-CD1 4.32Å; L250-L261 HydrophobicContact CD1-CD2 4.45Å; L250-L261 HydrophobicContact CD2-CD2 3.77Å; L250-L261 HydrophobicContact CG-CD2 4.24Å; L256-L261 HydrophobicContact CB-CB 4.47Å; N257-L261 WeakPolarHBondContact O-CB 3.36Å; N257-L261 PolarHBondContact O-N 3.26Å; L261-L265 HydrophobicContact CD1-CD1 3.86Å; L261-L265 HydrophobicContact CD1-CD2 4.4Å; L261-L265 HydrophobicContact CD1-CG 3.89Å; L261-L265 HydrophobicContact CG-CD1 3.93Å; L261-L265 HydrophobicContact CG-CG 4.27Å; L261-L265 VanDerWaalsContact O-CB 3.28Å; L261-L265 WeakPolarHBondContact O-CB 3.4Å; L261-L265 WeakPolarHBondContact O-CG 3.46Å; L261-L265 PolarHBondContact O-N 3.21Å; L261-R267 PolarHBondContact O-NH1 3Å; L261-L277 HydrophobicContact CB-CD2 4.3Å; L261-L277 HydrophobicContact CD2-CD2 4.03Å; L261-L277 HydrophobicContact CG-CD2 4.19Å; L261-L281 HydrophobicContact CD2-CD1 4.15Å; L261-L288 HydrophobicContact CD2-CD2 4.24Å
262	G	94.7	Very high	92.8	Very high	10 Å²	10	58.5 Å²	58.5	10%	0.103	33%	0.332	C	S	.	.	H	α-helix	trans	-61.9	-46.8	167.3	0	0	0	0	0	113.9	A258 S259 L260 L265 R266 R267	A258-G262 PolarHBondContact O-N 3.31Å; A258-G262 VanDerWaalsContact O-N 3.11Å; S259-G262 CarbonylContact O-C 3.57Å; S259-G262 VanDerWaalsContact O-CA 3.28Å; S259-G262 WeakPolarHBondContact O-CA 3.38Å; S259-G262 PolarHBondContact O-N 3.38Å; L260-G262 PolarHBondContact O-N 2.94Å; G262-L265 CarbonylContact O-C 3.59Å; G262-R266 PolarHBondContact O-N 3.15Å; G262-R266 VanDerWaalsContact O-N 3.07Å; G262-R267 VanDerWaalsContact CA-NH2 3.32Å; G262-R267 PolarHBondContact O-N 3.35Å
263	G	94.6	Very high	92.7	Very high	46 Å²	46	54.6 Å²	54.6	47%	0.474	31%	0.31	S	S	.	.	H	α-helix	trans	-66.1	-47.4	177.8	0	0	0	0	0	113.4	S259 L260 L265 R266	S259-G263 PolarHBondContact O-N 3.32Å; L260-G263 WeakPolarHBondContact O-CA 3.36Å; L260-G263 PolarHBondContact O-N 3.42Å; G263-L265 VanDerWaalsContact C-N 3.33Å; G263-L265 PolarHBondContact O-N 2.79Å; G263-R266 WeakPolarHBondContact O-CA 3.42Å; G263-R266 PolarHBondContact O-N 3Å
264	V	96.3	Very high	92.6	Very high	7 Å²	7	55.1 Å²	55.1	4%	0.042	32%	0.319	C	S	.	.	H	α-helix	trans	-60.1	-42.9	178.2	178.3	0	0	0	0	111.3	L256 L260 R266 T302 V305	L256-V264 HydrophobicContact CD1-CG2 4.15Å; L260-V264 WeakPolarHBondContact O-CG2 3.33Å; L260-V264 PolarHBondContact O-N 2.85Å; V264-R266 VanDerWaalsContact O-CG 3.26Å; V264-R266 WeakPolarHBondContact O-CG 3.35Å; V264-R266 PolarHBondContact O-N 3.41Å; V264-R266 PolarHBondContact O-NE 3.31Å; V264-R266 VanDerWaalsContact O-NE 3.1Å; V264-T302 WeakPolarHBondContact CG2-O 3.43Å; V264-V305 HydrophobicContact CG1-CG1 3.77Å
265	L	96.5	Very high	92.5	Very high	8 Å²	8	62 Å²	62	4%	0.042	34%	0.344	C	S	.	.	T	Hydrogen-bonded Turn	trans	-82.8	6.3	175.9	-56.1	-175.9	0	0	0	113.9	F223 V226 V241 L261 G262 G263 R267	F223-L265 HydrophobicContact CD1-CD1 3.96Å; F223-L265 HydrophobicContact CE1-CD1 3.68Å; V226-L265 HydrophobicContact CG1-CD2 4.47Å; V241-L265 HydrophobicContact CB-CD2 4.22Å; V241-L265 HydrophobicContact CG1-CD2 3.77Å; V241-L265 HydrophobicContact CG2-CD2 4.02Å; L261-L265 HydrophobicContact CD1-CD1 3.86Å; L261-L265 HydrophobicContact CD1-CD2 4.4Å; L261-L265 HydrophobicContact CD1-CG 3.89Å; L261-L265 HydrophobicContact CG-CD1 3.93Å; L261-L265 HydrophobicContact CG-CG 4.27Å; L261-L265 VanDerWaalsContact O-CB 3.28Å; L261-L265 WeakPolarHBondContact O-CB 3.4Å; L261-L265 WeakPolarHBondContact O-CG 3.46Å; L261-L265 PolarHBondContact O-N 3.21Å; G262-L265 CarbonylContact O-C 3.59Å; G263-L265 VanDerWaalsContact C-N 3.33Å; G263-L265 PolarHBondContact O-N 2.79Å; L265-R267 HydrophobicContact CB-CG 4.24Å; L265-R267 PolarHBondContact O-N 2.85Å
266	R	95	Very high	92.5	Very high	31 Å²	31	64.2 Å²	64.2	12%	0.117	36%	0.36	C	S	.	.	T	Hydrogen-bonded Turn	trans	60.3	21.4	165.1	-39.2	-179.1	-158.8	-144	-18.4	113.6	V226 P227 G262 G263 V264 E308	V226-R266 HydrophobicContact CB-CG 4.19Å; V226-R266 VanDerWaalsContact CG2-NE 3.32Å; P227-R266 WeakPolarHBondContact O-CD 3.33Å; P227-R266 PolarHBondContact O-NE 3.41Å; P227-R266 PolarHBondContact O-NH1 2.7Å; G262-R266 PolarHBondContact O-N 3.15Å; G262-R266 VanDerWaalsContact O-N 3.07Å; G263-R266 WeakPolarHBondContact O-CA 3.42Å; G263-R266 PolarHBondContact O-N 3Å; V264-R266 VanDerWaalsContact O-CG 3.26Å; V264-R266 WeakPolarHBondContact O-CG 3.35Å; V264-R266 PolarHBondContact O-N 3.41Å; V264-R266 PolarHBondContact O-NE 3.31Å; V264-R266 VanDerWaalsContact O-NE 3.1Å; R266-E308 IonicContact CZ-OE1 3.82Å; R266-E308 IonicContact CZ-OE2 3.7Å; R266-E308 VanDerWaalsContact CZ-OE2 3.31Å; R266-E308 IonicContact NH1-OE1 3.85Å; R266-E308 PolarHBondContact NH1-OE1 2.96Å; R266-E308 IonicContact NH1-OE2 3.47Å; R266-E308 PolarHBondContact NH1-OE2 2.93Å; R266-E308 VanDerWaalsContact NH1-OE2 3.15Å; R266-E308 IonicContact NH2-OE1 3.52Å; R266-E308 IonicContact NH2-OE2 2.79Å; R266-E308 PolarHBondContact NH2-OE2 2.98Å
267	R	92.7	Very high	92.4	Very high	89 Å²	89	64.2 Å²	64.2	34%	0.336	36%	0.36	S	S	.	.			trans	-72.8	138.8	-177.7	-59.5	-164.5	-49.4	-69.1	-11.7	109.7	L261 G262 L265	L261-R267 PolarHBondContact O-NH1 3Å; G262-R267 VanDerWaalsContact CA-NH2 3.32Å; G262-R267 PolarHBondContact O-N 3.35Å; L265-R267 HydrophobicContact CB-CG 4.24Å; L265-R267 PolarHBondContact O-N 2.85Å
268	A	88.7	Confident	92.5	Very high	92 Å²	92	66 Å²	66	76%	0.76	36%	0.363	S	S	*	.			trans	-56.1	143.8	174.1	0	0	0	0	0	111.4	S270	A268-S270 PolarHBondContact O-N 3.25Å; A268-S270 VanDerWaalsContact O-N 3.13Å
269	K	88.2	Confident	92.6	Very high	222 Å²	222	70.1 Å²	70.1	97%	0.965	38%	0.379	S	S	*	.			trans	-73.9	104.3	178.2	-174.8	-179	179.9	-177.5	0	109.6
270	S	89.4	Confident	92.8	Very high	70 Å²	70	70.1 Å²	70.1	49%	0.49	37%	0.367	S	S	.	.			trans	-116.2	152.5	174	68.9	0	0	0	0	111.7	A268 N272 G273	A268-S270 PolarHBondContact O-N 3.25Å; A268-S270 VanDerWaalsContact O-N 3.13Å; S270-N272 PolarHBondContact O-N 3Å; S270-N272 VanDerWaalsContact O-N 3.13Å; S270-G273 PolarHBondContact O-N 3.09Å; S270-G273 WeakPolarHBondContact OG-CA 3.33Å; S270-G273 PolarHBondContact OG-N 3.28Å; S270-G273 VanDerWaalsContact OG-N 3.1Å
271	K	90.2	Very high	92.8	Very high	209 Å²	209	67.9 Å²	67.9	91%	0.909	36%	0.355	S	S	*	.	T	Hydrogen-bonded Turn	trans	-51.9	-37.3	-179.5	-177.2	177.4	178	179.5	0	112.7
272	N	90.9	Very high	92.8	Very high	94 Å²	94	73.5 Å²	73.5	50%	0.503	39%	0.386	S	S	.	.	T	Hydrogen-bonded Turn	trans	-101.7	3.6	-179.3	-64	-22.7	0	0	0	113.5	S270 G274 R275 S276	S270-N272 PolarHBondContact O-N 3Å; S270-N272 VanDerWaalsContact O-N 3.13Å; N272-G274 VanDerWaalsContact C-N 3.25Å; N272-G274 PolarHBondContact O-N 3.37Å; N272-G274 VanDerWaalsContact O-N 3.13Å; N272-R275 WeakPolarHBondContact O-CA 3.49Å; N272-R275 WeakPolarHBondContact O-CB 3.45Å; N272-R275 PolarHBondContact O-N 3.36Å; N272-S276 PolarHBondContact O-N 3.03Å
273	G	90.2	Very high	92.7	Very high	14 Å²	14	81 Å²	81	14%	0.144	42%	0.415	C	S	.	.	H	α-helix	trans	-61.6	-27.9	-168.9	0	0	0	0	0	115	S270 L277	S270-G273 PolarHBondContact O-N 3.09Å; S270-G273 WeakPolarHBondContact OG-CA 3.33Å; S270-G273 PolarHBondContact OG-N 3.28Å; S270-G273 VanDerWaalsContact OG-N 3.1Å; G273-L277 WeakPolarHBondContact O-CB 3.34Å; G273-L277 PolarHBondContact O-N 3.36Å; G273-L277 VanDerWaalsContact O-N 3.12Å
274	G	90.8	Very high	92.6	Very high	30 Å²	30	79.9 Å²	79.9	31%	0.309	40%	0.398	S	S	.	.	H	α-helix	trans	-74.2	-29.4	171.5	0	0	0	0	0	113.8	N272 R278	N272-G274 VanDerWaalsContact C-N 3.25Å; N272-G274 PolarHBondContact O-N 3.37Å; N272-G274 VanDerWaalsContact O-N 3.13Å; G274-R278 WeakPolarHBondContact O-CG 3.38Å; G274-R278 PolarHBondContact O-N 2.9Å; G274-R278 PolarHBondContact O-NH1 2.7Å
275	R	92.6	Very high	92.3	Very high	149 Å²	149	82.1 Å²	82.1	56%	0.562	42%	0.422	S	S	*	.	H	α-helix	trans	-77	-50.9	175.2	-169	-166.3	-69.9	-177.6	-4.1	110.3	N272 L277 R278 E279	N272-R275 WeakPolarHBondContact O-CA 3.49Å; N272-R275 WeakPolarHBondContact O-CB 3.45Å; N272-R275 PolarHBondContact O-N 3.36Å; R275-L277 VanDerWaalsContact C-N 3.27Å; R275-L277 PolarHBondContact O-N 3.25Å; R275-R278 WeakPolarHBondContact O-CA 3.44Å; R275-R278 WeakPolarHBondContact O-CB 3.44Å; R275-R278 PolarHBondContact O-N 3.36Å; R275-E279 WeakPolarHBondContact CD-OE1 3.42Å; R275-E279 VanDerWaalsContact CG-OE1 3.22Å; R275-E279 WeakPolarHBondContact CG-OE1 3.47Å; R275-E279 WeakPolarHBondContact O-CG 3.47Å; R275-E279 PolarHBondContact O-N 3Å
276	S	93.4	Very high	92.1	Very high	66 Å²	66	82.3 Å²	82.3	46%	0.462	42%	0.423	S	S	.	.	H	α-helix	trans	-57.1	-37.4	176.5	169.3	0	0	0	0	112.6	N272 E279 K280	N272-S276 PolarHBondContact O-N 3.03Å; S276-E279 PolarHBondContact O-N 3.45Å; S276-K280 WeakPolarHBondContact O-CB 3.49Å; S276-K280 PolarHBondContact O-N 2.91Å
277	L	93.9	Very high	91.9	Very high	3 Å²	3	86.6 Å²	86.6	2%	0.016	45%	0.448	C	S	.	.	H	α-helix	trans	-60.8	-49.4	170.9	174.9	61.4	0	0	0	111.8	F223 A258 L261 G273 R275 E279 K280 L281 L288	F223-L277 HydrophobicContact CE1-CD1 4.23Å; F223-L277 HydrophobicContact CZ-CD1 4.15Å; A258-L277 HydrophobicContact CB-CD2 4.11Å; L261-L277 HydrophobicContact CB-CD2 4.3Å; L261-L277 HydrophobicContact CD2-CD2 4.03Å; L261-L277 HydrophobicContact CG-CD2 4.19Å; G273-L277 WeakPolarHBondContact O-CB 3.34Å; G273-L277 PolarHBondContact O-N 3.36Å; G273-L277 VanDerWaalsContact O-N 3.12Å; R275-L277 VanDerWaalsContact C-N 3.27Å; R275-L277 PolarHBondContact O-N 3.25Å; L277-E279 VanDerWaalsContact C-N 3.31Å; L277-E279 PolarHBondContact O-N 3.26Å; L277-K280 PolarHBondContact O-N 3.46Å; L277-K280 VanDerWaalsContact O-N 3.13Å; L277-L281 HydrophobicContact CD1-CD1 3.88Å; L277-L281 HydrophobicContact CD1-CD2 4.29Å; L277-L281 HydrophobicContact CD1-CG 3.86Å; L277-L281 HydrophobicContact CD2-CD1 4.32Å; L277-L281 HydrophobicContact CG-CD1 3.79Å; L277-L281 HydrophobicContact CG-CG 4.22Å; L277-L281 VanDerWaalsContact O-CG 3.27Å; L277-L281 WeakPolarHBondContact O-CG 3.48Å; L277-L281 PolarHBondContact O-N 3.17Å; L277-L288 HydrophobicContact CD2-CD2 4.14Å
278	R	94.1	Very high	91.8	Very high	83 Å²	83	82.6 Å²	82.6	31%	0.313	43%	0.434	S	S	.	.	H	α-helix	trans	-60.4	-42.9	179.7	-72.5	-174.8	-64.4	-91.8	4.2	111.5	G274 R275 K280 L281 D282 L288	G274-R278 WeakPolarHBondContact O-CG 3.38Å; G274-R278 PolarHBondContact O-N 2.9Å; G274-R278 PolarHBondContact O-NH1 2.7Å; R275-R278 WeakPolarHBondContact O-CA 3.44Å; R275-R278 WeakPolarHBondContact O-CB 3.44Å; R275-R278 PolarHBondContact O-N 3.36Å; R278-K280 VanDerWaalsContact C-N 3.32Å; R278-K280 PolarHBondContact O-N 3.23Å; R278-L281 PolarHBondContact O-N 3.22Å; R278-D282 WeakPolarHBondContact O-CB 3.41Å; R278-D282 PolarHBondContact O-N 2.94Å; R278-L288 WeakPolarHBondContact CD-O 3.18Å; R278-L288 HydrophobicContact CG-CB 4.28Å; R278-L288 HydrophobicContact CG-CG 4.43Å; R278-L288 WeakPolarHBondContact CG-O 3.43Å
279	E	94.1	Very high	91.7	Very high	102 Å²	102	80.7 Å²	80.7	48%	0.477	41%	0.414	S	S	.	.	H	α-helix	trans	-61.6	-37	174.6	-67.9	161.6	-176.6	0	0	112.4	R275 S276 L277 K283	R275-E279 WeakPolarHBondContact CD-OE1 3.42Å; R275-E279 VanDerWaalsContact CG-OE1 3.22Å; R275-E279 WeakPolarHBondContact CG-OE1 3.47Å; R275-E279 WeakPolarHBondContact O-CG 3.47Å; R275-E279 PolarHBondContact O-N 3Å; S276-E279 PolarHBondContact O-N 3.45Å; L277-E279 VanDerWaalsContact C-N 3.31Å; L277-E279 PolarHBondContact O-N 3.26Å; E279-K283 WeakPolarHBondContact O-CG 3.45Å; E279-K283 PolarHBondContact O-N 2.96Å
280	K	93.5	Very high	91.5	Very high	99 Å²	99	73.8 Å²	73.8	43%	0.43	40%	0.398	S	S	.	.	H	α-helix	trans	-72.3	-34.3	175.2	-162.1	-174	174.7	-174	0	112.5	F223 S276 L277 R278	F223-K280 HydrophobicContact CE1-CD 4.4Å; F223-K280 HydrophobicContact CE2-CB 4.36Å; F223-K280 HydrophobicContact CE2-CD 3.72Å; F223-K280 HydrophobicContact CE2-CG 3.72Å; F223-K280 HydrophobicContact CZ-CB 4.18Å; F223-K280 HydrophobicContact CZ-CD 3.64Å; F223-K280 HydrophobicContact CZ-CG 3.88Å; F223-K280 PolarHBondContact O-NZ 3.06Å; S276-K280 WeakPolarHBondContact O-CB 3.49Å; S276-K280 PolarHBondContact O-N 2.91Å; L277-K280 PolarHBondContact O-N 3.46Å; L277-K280 VanDerWaalsContact O-N 3.13Å; R278-K280 VanDerWaalsContact C-N 3.32Å; R278-K280 PolarHBondContact O-N 3.23Å
281	L	94.9	Very high	91.1	Very high	0 Å²	0	74.2 Å²	74.2	0%	0	41%	0.414	C	S	.	.	H	α-helix	trans	-71.5	-41.1	176	-66.6	171.5	0	0	0	111.8	F223 V246 L250 L261 L277 R278 K283 I284 G285 L286 L288	F223-L281 HydrophobicContact CE1-CD2 4.24Å; F223-L281 HydrophobicContact CE2-CD2 4.02Å; F223-L281 HydrophobicContact CZ-CD2 3.65Å; F223-L281 HydrophobicContact CZ-CG 4.26Å; V246-L281 HydrophobicContact CG1-CD2 3.49Å; V246-L281 VanDerWaalsContact CG1-CD2 3.49Å; L250-L281 HydrophobicContact CD1-CD1 4.14Å; L261-L281 HydrophobicContact CD2-CD1 4.15Å; L277-L281 HydrophobicContact CD1-CD1 3.88Å; L277-L281 HydrophobicContact CD1-CD2 4.29Å; L277-L281 HydrophobicContact CD1-CG 3.86Å; L277-L281 HydrophobicContact CD2-CD1 4.32Å; L277-L281 HydrophobicContact CG-CD1 3.79Å; L277-L281 HydrophobicContact CG-CG 4.22Å; L277-L281 VanDerWaalsContact O-CG 3.27Å; L277-L281 WeakPolarHBondContact O-CG 3.48Å; L277-L281 PolarHBondContact O-N 3.17Å; R278-L281 PolarHBondContact O-N 3.22Å; L281-K283 VanDerWaalsContact C-N 3.29Å; L281-K283 PolarHBondContact O-N 3.4Å; L281-I284 HydrophobicContact CD2-CD1 4.37Å; L281-I284 CarbonylContact O-C 3.17Å; L281-I284 WeakPolarHBondContact O-CG1 3.37Å; L281-I284 PolarHBondContact O-N 3.4Å; L281-G285 PolarHBondContact O-N 2.86Å; L281-L286 CarbonylContact C-O 3.58Å; L281-L286 HydrophobicContact CB-CB 4.1Å; L281-L286 VanDerWaalsContact CB-O 3.23Å; L281-L286 WeakPolarHBondContact CB-O 3.4Å; L281-L286 HydrophobicContact CD2-CB 4.29Å; L281-L286 HydrophobicContact CD2-CD1 4.27Å; L281-L286 PolarHBondContact O-N 3.1Å; L281-L288 HydrophobicContact CD1-CB 3.72Å; L281-L288 HydrophobicContact CD1-CD2 3.59Å; L281-L288 HydrophobicContact CD1-CG 4.34Å
282	D	93.6	Very high	90.9	Very high	120 Å²	120	68.7 Å²	68.7	64%	0.642	39%	0.387	S	S	*	.	H	α-helix	trans	-59.5	-40.1	178.4	-165.3	57.1	0	0	0	111.6	R278 I284 G285 L286	R278-D282 WeakPolarHBondContact O-CB 3.41Å; R278-D282 PolarHBondContact O-N 2.94Å; D282-I284 PolarHBondContact O-N 3.41Å; D282-G285 PolarHBondContact O-N 2.84Å; D282-L286 PolarHBondContact N-O 3.45Å
283	K	92.6	Very high	90.5	Very high	168 Å²	168	75 Å²	75	73%	0.73	40%	0.404	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.2	-25.4	174.2	-74.4	175.3	-178.7	-171.8	0	115	E279 L281	E279-K283 WeakPolarHBondContact O-CG 3.45Å; E279-K283 PolarHBondContact O-N 2.96Å; L281-K283 VanDerWaalsContact C-N 3.29Å; L281-K283 PolarHBondContact O-N 3.4Å
284	I	92.2	Very high	90.2	Very high	22 Å²	22	79 Å²	79	11%	0.113	42%	0.417	C	S	.	.	T	Hydrogen-bonded Turn	trans	-104.9	13	176.9	61.7	162.6	0	0	0	112.4	M217 F223 V243 L281 D282 L286	M217-I284 VanDerWaalsContact CG-O 3.3Å; M217-I284 WeakPolarHBondContact CG-O 3.36Å; M217-I284 VanDerWaalsContact SD-O 3.38Å; F223-I284 HydrophobicContact CD2-CD1 3.5Å; F223-I284 VanDerWaalsContact CD2-CD1 3.5Å; F223-I284 HydrophobicContact CE2-CD1 3.65Å; F223-I284 HydrophobicContact CE2-CG1 4.34Å; F223-I284 HydrophobicContact CG-CD1 4.44Å; V243-I284 HydrophobicContact CB-CD1 4.45Å; V243-I284 HydrophobicContact CG1-CD1 3.94Å; V243-I284 HydrophobicContact CG2-CD1 3.85Å; L281-I284 HydrophobicContact CD2-CD1 4.37Å; L281-I284 CarbonylContact O-C 3.17Å; L281-I284 WeakPolarHBondContact O-CG1 3.37Å; L281-I284 PolarHBondContact O-N 3.4Å; D282-I284 PolarHBondContact O-N 3.41Å; I284-L286 HydrophobicContact CD1-CB 4.46Å; I284-L286 HydrophobicContact CD1-CD1 3.76Å; I284-L286 HydrophobicContact CD1-CG 4.06Å; I284-L286 HydrophobicContact CG1-CB 4.32Å; I284-L286 HydrophobicContact CG1-CD1 4.45Å; I284-L286 HydrophobicContact CG1-CG 4.22Å; I284-L286 PolarHBondContact O-N 2.96Å
285	G	91.4	Very high	89.9	Confident	53 Å²	53	81 Å²	81	55%	0.546	43%	0.431	S	S	.	.	T	Hydrogen-bonded Turn	trans	78.3	11.3	179.3	0	0	0	0	0	115.4	L281 D282	L281-G285 PolarHBondContact O-N 2.86Å; D282-G285 PolarHBondContact O-N 2.84Å
286	L	92.8	Very high	89.7	Confident	12 Å²	12	75 Å²	75	6%	0.063	41%	0.413	C	S	.	.			trans	-98.4	117.4	177.7	-68.5	-173.2	0	0	0	112	M217 V243 V246 Q247 L250 L281 D282 I284	M217-L286 HydrophobicContact CE-CD2 4.13Å; M217-L286 HydrophobicContact SD-CD1 4.43Å; M217-L286 HydrophobicContact SD-CD2 3.49Å; M217-L286 WeakPolarHBondContact SD-CD2 3.44Å; M217-L286 HydrophobicContact SD-CG 3.74Å; V243-L286 HydrophobicContact CG1-CD1 4.25Å; V246-L286 HydrophobicContact CB-CD1 3.99Å; V246-L286 HydrophobicContact CG1-CD1 3.69Å; Q247-L286 HydrophobicContact CB-CD1 4.33Å; Q247-L286 HydrophobicContact CB-CD2 3.98Å; Q247-L286 HydrophobicContact CG-CD2 3.89Å; L250-L286 HydrophobicContact CD1-CB 4.44Å; L281-L286 CarbonylContact C-O 3.58Å; L281-L286 HydrophobicContact CB-CB 4.1Å; L281-L286 VanDerWaalsContact CB-O 3.23Å; L281-L286 WeakPolarHBondContact CB-O 3.4Å; L281-L286 HydrophobicContact CD2-CB 4.29Å; L281-L286 HydrophobicContact CD2-CD1 4.27Å; L281-L286 PolarHBondContact O-N 3.1Å; D282-L286 PolarHBondContact N-O 3.45Å; I284-L286 HydrophobicContact CD1-CB 4.46Å; I284-L286 HydrophobicContact CD1-CD1 3.76Å; I284-L286 HydrophobicContact CD1-CG 4.06Å; I284-L286 HydrophobicContact CG1-CB 4.32Å; I284-L286 HydrophobicContact CG1-CD1 4.45Å; I284-L286 HydrophobicContact CG1-CG 4.22Å; I284-L286 PolarHBondContact O-N 2.96Å
287	N	90.3	Very high	89.5	Confident	121 Å²	121	79.9 Å²	79.9	65%	0.647	43%	0.428	S	S	*	.			trans	-90.5	123.9	176.9	-175.6	2.4	0	0	0	112.2
288	L	90	Very high	89.5	Confident	5 Å²	5	82.9 Å²	82.9	3%	0.026	45%	0.447	C	S	.	.			trans	-121.5	92	172.3	178.9	48.8	0	0	0	110.9	L250 A258 L261 L277 R278 L281	L250-L288 HydrophobicContact CD1-CB 4.33Å; L250-L288 HydrophobicContact CD2-CD1 3.78Å; L250-L288 HydrophobicContact CD2-CD2 3.95Å; L250-L288 HydrophobicContact CD2-CG 4.31Å; A258-L288 HydrophobicContact CB-CD2 3.72Å; A258-L288 HydrophobicContact CB-CG 4.34Å; L261-L288 HydrophobicContact CD2-CD2 4.24Å; L277-L288 HydrophobicContact CD2-CD2 4.14Å; R278-L288 WeakPolarHBondContact CD-O 3.18Å; R278-L288 HydrophobicContact CG-CB 4.28Å; R278-L288 HydrophobicContact CG-CG 4.43Å; R278-L288 WeakPolarHBondContact CG-O 3.43Å; L281-L288 HydrophobicContact CD1-CB 3.72Å; L281-L288 HydrophobicContact CD1-CD2 3.59Å; L281-L288 HydrophobicContact CD1-CG 4.34Å
289	P	85.9	Confident	89.5	Confident	52 Å²	52	82.2 Å²	82.2	34%	0.338	45%	0.452	S	S	.	.			trans	-65	144.3	-176	24.1	-32.5	0	0	0	112.4	R292	P289-R292 HydrophobicContact CG-CB 4.38Å
290	A	85.7	Confident	89.6	Confident	77 Å²	77	84.6 Å²	84.6	64%	0.636	47%	0.467	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.4	147.3	172.7	0	0	0	0	0	110.8	R292	A290-R292 PolarHBondContact O-N 3.03Å
291	G	80.9	Confident	89.7	Confident	80 Å²	80	82 Å²	82	83%	0.825	46%	0.458	S	S	*	.	T	Hydrogen-bonded Turn	trans	76.9	-5.5	178.6	0	0	0	0	0	116.3	R293	G291-R293 PolarHBondContact O-N 2.88Å
292	R	84.4	Confident	89.8	Confident	92 Å²	92	82.2 Å²	82.2	35%	0.347	46%	0.459	S	S	.	.	P	Polyproline II helix	trans	-53.4	125.3	175.7	179.1	173.4	-74.9	-179	1.4	111.2	L250 N257 P289 A290	L250-R292 PolarHBondContact O-NH1 3.11Å; N257-R292 VanDerWaalsContact CB-O 3.29Å; N257-R292 WeakPolarHBondContact CB-O 3.35Å; P289-R292 HydrophobicContact CG-CB 4.38Å; A290-R292 PolarHBondContact O-N 3.03Å
293	R	82.7	Confident	89.8	Confident	226 Å²	226	79.1 Å²	79.1	85%	0.853	45%	0.447	S	S	*	.	P	Polyproline II helix	trans	-80.7	148.4	168.3	-62	-177.4	-177.5	-177.7	1.7	109.2	G291	G291-R293 PolarHBondContact O-N 2.88Å
294	K	85.1	Confident	90.1	Very high	98 Å²	98	71.4 Å²	71.4	43%	0.426	41%	0.414	S	S	.	.	P	Polyproline II helix	trans	-67.9	151.9	170.5	72.1	-171.7	-164.8	-179.1	0	110	L260 A296 V298	L260-K294 HydrophobicContact CD1-CB 3.97Å; L260-K294 HydrophobicContact CD1-CD 3.73Å; L260-K294 HydrophobicContact CD1-CG 4.46Å; K294-A296 WeakPolarHBondContact CE-O 3.47Å; K294-V298 HydrophobicContact CD-CG2 3.77Å; K294-V298 VanDerWaalsContact NZ-CG2 3.34Å
295	A	84.3	Confident	90.3	Very high	72 Å²	72	70.4 Å²	70.4	60%	0.595	41%	0.408	S	S	*	.			trans	-96.3	-41.3	177	0	0	0	0	0	112.2	P253 E254 C255	P253-A295 WeakPolarHBondContact O-CB 3.32Å; E254-A295 PolarHBondContact O-N 2.78Å; C255-A295 HydrophobicContact CB-CB 3.71Å
296	A	87.3	Confident	90.5	Very high	23 Å²	23	68.4 Å²	68.4	19%	0.19	39%	0.385	C	S	.	.	S	Bend	trans	-89.8	160.8	-178.4	0	0	0	0	0	114.7	K294 I395	K294-A296 WeakPolarHBondContact CE-O 3.47Å; A296-I395 HydrophobicContact CB-CD1 3.58Å
297	H	90.8	Very high	90.6	Very high	169 Å²	169	69.3 Å²	69.3	78%	0.782	40%	0.397	S	S	*	.	P	Polyproline II helix	trans	-64.1	135.7	161.5	-70.3	-96	0	0	0	109.6
298	V	92	Very high	90.9	Very high	66 Å²	66	63.9 Å²	63.9	40%	0.4	37%	0.368	S	S	.	.	P	Polyproline II helix	trans	-87	122.4	177.3	170.7	0	0	0	0	107.5	L260 K294 T302	L260-V298 HydrophobicContact CD1-CG2 4.05Å; L260-V298 HydrophobicContact CD2-CG2 4.21Å; K294-V298 HydrophobicContact CD-CG2 3.77Å; K294-V298 VanDerWaalsContact NZ-CG2 3.34Å; V298-T302 HydrophobicContact CG1-CG2 4.05Å; V298-T302 HydrophobicContact CG2-CG2 4.38Å
299	T	94.8	Very high	91.2	Very high	69 Å²	69	63.7 Å²	63.7	42%	0.423	37%	0.367	S	S	.	.			trans	-110.2	-179.5	176.8	69	0	0	0	0	109.9	L301 T302	T299-L301 VanDerWaalsContact C-N 3.25Å; T299-L301 PolarHBondContact O-N 3.03Å; T299-L301 PolarHBondContact OG1-N 3.43Å; T299-T302 PolarHBondContact N-OG1 3.43Å; T299-T302 WeakPolarHBondContact O-CB 3.46Å; T299-T302 PolarHBondContact O-N 3.11Å; T299-T302 PolarHBondContact OG1-N 2.95Å
300	L	95.9	Very high	91.7	Very high	153 Å²	153	63.1 Å²	63.1	80%	0.801	36%	0.363	S	S	*	.	S	Bend	trans	-63.4	-33.8	169.4	-63.6	179	0	0	0	111.7	T302 S303	L300-T302 VanDerWaalsContact C-N 3.31Å; L300-T302 PolarHBondContact O-N 3.02Å; L300-S303 WeakPolarHBondContact O-CB 3.48Å; L300-S303 PolarHBondContact O-N 3.07Å; L300-S303 PolarHBondContact O-OG 3.33Å
301	L	96.4	Very high	92.1	Very high	43 Å²	43	62.4 Å²	62.4	23%	0.225	35%	0.346	C	S	.	.	G	3₁₀ helix	trans	-62.8	-36.2	177.8	-62.6	175.2	0	0	0	112	T299 S303 L304 T396 H397 F399	T299-L301 VanDerWaalsContact C-N 3.25Å; T299-L301 PolarHBondContact O-N 3.03Å; T299-L301 PolarHBondContact OG1-N 3.43Å; L301-S303 PolarHBondContact O-N 3.49Å; L301-L304 HydrophobicContact CD2-CD1 4.08Å; L301-L304 WeakPolarHBondContact O-CB 3.38Å; L301-L304 PolarHBondContact O-N 3.46Å; L301-T396 HydrophobicContact CD1-CG2 3.86Å; L301-H397 PolarHBondContact O-CE1 3.12Å; L301-H397 PolarHBondContact O-ND1 3.36Å; L301-F399 HydrophobicContact CD1-CD1 4.36Å; L301-F399 HydrophobicContact CD2-CD1 4.03Å; L301-F399 HydrophobicContact CD2-CG 4.4Å
302	T	96	Very high	92.9	Very high	5 Å²	5	61.2 Å²	61.2	3%	0.031	32%	0.32	C	S	.	.	G	3₁₀ helix	trans	-52.5	-27.2	172.8	-57.1	0	0	0	0	113.3	R249 E254 L256 V264 V298 T299 L300 H397	R249-T302 PolarHBondContact NH1-O 3.41Å; E254-T302 WeakPolarHBondContact OE1-CG2 3.44Å; E254-T302 PolarHBondContact OE1-OG1 3.47Å; L256-T302 HydrophobicContact CD2-CG2 4.22Å; V264-T302 WeakPolarHBondContact CG2-O 3.43Å; V298-T302 HydrophobicContact CG1-CG2 4.05Å; V298-T302 HydrophobicContact CG2-CG2 4.38Å; T299-T302 PolarHBondContact N-OG1 3.43Å; T299-T302 WeakPolarHBondContact O-CB 3.46Å; T299-T302 PolarHBondContact O-N 3.11Å; T299-T302 PolarHBondContact OG1-N 2.95Å; L300-T302 VanDerWaalsContact C-N 3.31Å; L300-T302 PolarHBondContact O-N 3.02Å; T302-H397 WeakPolarHBondContact CA-CE1 3.34Å; T302-H397 PolarHBondContact N-CE1 3.21Å
303	S	95.5	Very high	93.5	Very high	55 Å²	55	56.9 Å²	56.9	39%	0.385	30%	0.304	S	S	.	.	G	3₁₀ helix	trans	-78	-19.3	179.6	76	0	0	0	0	114.6	L300 L301	L300-S303 WeakPolarHBondContact O-CB 3.48Å; L300-S303 PolarHBondContact O-N 3.07Å; L300-S303 PolarHBondContact O-OG 3.33Å; L301-S303 PolarHBondContact O-N 3.49Å
304	L	96.9	Very high	94.2	Very high	7 Å²	7	53.3 Å²	53.3	4%	0.037	29%	0.29	C	S	.	.	S	Bend	trans	-80.4	147.9	178.1	-57.2	-179.1	0	0	0	110.3	L230 R249 L301 E308 A309 L312	L230-L304 HydrophobicContact CD1-CD2 4.23Å; L230-L304 HydrophobicContact CG-CD2 4.37Å; R249-L304 PolarHBondContact NH1-O 3.3Å; R249-L304 PolarHBondContact NH2-O 2.94Å; L301-L304 HydrophobicContact CD2-CD1 4.08Å; L301-L304 WeakPolarHBondContact O-CB 3.38Å; L301-L304 PolarHBondContact O-N 3.46Å; L304-E308 WeakPolarHBondContact CA-OE2 3.49Å; L304-E308 HydrophobicContact CB-CB 4.21Å; L304-E308 HydrophobicContact CD2-CB 4.21Å; L304-A309 HydrophobicContact CB-CB 4.35Å; L304-A309 HydrophobicContact CD1-CB 4.29Å; L304-L312 HydrophobicContact CD1-CD2 3.97Å
305	V	96.9	Very high	94.8	Very high	0 Å²	0	52.5 Å²	52.5	0%	0	29%	0.291	C	S	.	.			trans	-86.9	159.2	160.4	-67.5	0	0	0	0	110	V226 Y239 V241 E245 V264 G307 E308 A309	V226-V305 HydrophobicContact CG2-CG1 4.04Å; V226-V305 HydrophobicContact CG2-CG2 3.85Å; Y239-V305 HydrophobicContact CG-CG2 4.27Å; V241-V305 HydrophobicContact CG2-CB 4.06Å; V241-V305 HydrophobicContact CG2-CG1 3.56Å; V241-V305 HydrophobicContact CG2-CG2 4.38Å; E245-V305 VanDerWaalsContact OE1-CA 3.28Å; E245-V305 WeakPolarHBondContact OE1-CA 3.38Å; E245-V305 WeakPolarHBondContact OE1-CB 3.48Å; V264-V305 HydrophobicContact CG1-CG1 3.77Å; V305-G307 PolarHBondContact O-N 3.21Å; V305-G307 VanDerWaalsContact O-N 3.16Å; V305-E308 HydrophobicContact CG2-CB 4.43Å; V305-E308 HydrophobicContact CG2-CG 3.91Å; V305-E308 PolarHBondContact N-OE2 3.17Å; V305-E308 WeakPolarHBondContact O-CB 3.49Å; V305-E308 PolarHBondContact O-N 2.9Å; V305-A309 PolarHBondContact O-N 3.3Å
306	E	96.5	Very high	95.4	Very high	12 Å²	12	53 Å²	53	6%	0.056	28%	0.28	C	S	.	.	H	α-helix	trans	-53.5	-39.9	-176.8	-74.7	174.3	-145.6	0	0	112.2	E245 R248 E308 A309 V310 G373 H397	E245-E306 HydrophobicContact CG-CG 4.23Å; E245-E306 WeakPolarHBondContact CG-OE1 3.36Å; E245-E306 PolarHBondContact OE1-N 3.28Å; R248-E306 IonicContact CZ-OE1 2Å; R248-E306 IonicContact CZ-OE2 3.3Å; R248-E306 IonicContact NE-OE1 3.69Å; R248-E306 PolarHBondContact NE-OE1 2.82Å; R248-E306 IonicContact NE-OE2 2.74Å; R248-E306 IonicContact NH2-OE1 3.85Å; R248-E306 PolarHBondContact NH2-OE1 2.74Å; R248-E306 IonicContact NH2-OE2 3.32Å; R248-E306 PolarHBondContact NH2-OE2 3.34Å; E306-E308 VanDerWaalsContact C-N 3.29Å; E306-E308 PolarHBondContact O-N 3.5Å; E306-A309 PolarHBondContact O-N 3.45Å; E306-V310 WeakPolarHBondContact O-CB 3.48Å; E306-V310 VanDerWaalsContact O-CG2 3.31Å; E306-V310 WeakPolarHBondContact O-CG2 3.31Å; E306-V310 PolarHBondContact O-N 3.09Å; E306-G373 WeakPolarHBondContact OE2-CA 3.33Å; E306-G373 PolarHBondContact OE2-N 2.89Å; E306-H397 HydrophobicContact CG-CB 3.98Å
307	G	95.3	Very high	96	Very high	31 Å²	31	53.6 Å²	53.6	32%	0.32	29%	0.285	S	S	.	.	H	α-helix	trans	-60.1	-34.4	175.7	0	0	0	0	0	114.2	Y239 V305 H311	Y239-G307 VanDerWaalsContact CD1-C 3.43Å; Y239-G307 WeakPolarHBondContact CE1-O 3.45Å; V305-G307 PolarHBondContact O-N 3.21Å; V305-G307 VanDerWaalsContact O-N 3.16Å; G307-H311 WeakPolarHBondContact O-CB 3.48Å; G307-H311 PolarHBondContact O-N 3.02Å
308	E	96	Very high	96.3	Very high	7 Å²	7	53 Å²	53	3%	0.033	28%	0.277	C	S	.	.	H	α-helix	trans	-77.5	-41.4	174.8	-69.9	174.8	125.7	0	0	112.1	G228 R229 Y239 R266 L304 V305 E306 V310 H311 L312	G228-E308 VanDerWaalsContact CA-OE1 3.28Å; G228-E308 WeakPolarHBondContact CA-OE1 3.4Å; R229-E308 PolarHBondContact N-OE1 2.87Å; Y239-E308 HydrophobicContact CD1-CG 4.01Å; Y239-E308 HydrophobicContact CD2-CG 3.5Å; Y239-E308 HydrophobicContact CE1-CG 3.96Å; Y239-E308 HydrophobicContact CE2-CG 3.46Å; Y239-E308 VanDerWaalsContact CE2-CG 3.46Å; Y239-E308 HydrophobicContact CG-CG 3.78Å; R266-E308 IonicContact CZ-OE1 3.82Å; R266-E308 IonicContact CZ-OE2 3.7Å; R266-E308 VanDerWaalsContact CZ-OE2 3.31Å; R266-E308 IonicContact NH1-OE1 3.85Å; R266-E308 PolarHBondContact NH1-OE1 2.96Å; R266-E308 IonicContact NH1-OE2 3.47Å; R266-E308 PolarHBondContact NH1-OE2 2.93Å; R266-E308 VanDerWaalsContact NH1-OE2 3.15Å; R266-E308 IonicContact NH2-OE1 3.52Å; R266-E308 IonicContact NH2-OE2 2.79Å; R266-E308 PolarHBondContact NH2-OE2 2.98Å; L304-E308 WeakPolarHBondContact CA-OE2 3.49Å; L304-E308 HydrophobicContact CB-CB 4.21Å; L304-E308 HydrophobicContact CD2-CB 4.21Å; V305-E308 HydrophobicContact CG2-CB 4.43Å; V305-E308 HydrophobicContact CG2-CG 3.91Å; V305-E308 PolarHBondContact N-OE2 3.17Å; V305-E308 WeakPolarHBondContact O-CB 3.49Å; V305-E308 PolarHBondContact O-N 2.9Å; E306-E308 VanDerWaalsContact C-N 3.29Å; E306-E308 PolarHBondContact O-N 3.5Å; E308-V310 VanDerWaalsContact C-N 3.32Å; E308-V310 PolarHBondContact O-N 3.04Å; E308-H311 PolarHBondContact O-N 3.24Å; E308-L312 VanDerWaalsContact O-CB 3.29Å; E308-L312 WeakPolarHBondContact O-CB 3.41Å; E308-L312 PolarHBondContact O-N 3.33Å
309	A	97	Very high	96.6	Very high	0 Å²	0	53.5 Å²	53.5	0%	0	28%	0.28	C	S	.	.	H	α-helix	trans	-63.5	-40.1	-179.6	0	0	0	0	0	111.3	L304 V305 E306 A313 H397 F399	L304-A309 HydrophobicContact CB-CB 4.35Å; L304-A309 HydrophobicContact CD1-CB 4.29Å; V305-A309 PolarHBondContact O-N 3.3Å; E306-A309 PolarHBondContact O-N 3.45Å; A309-A313 WeakPolarHBondContact O-CB 3.32Å; A309-A313 PolarHBondContact O-N 3.46Å; A309-A313 VanDerWaalsContact O-N 3.09Å; A309-H397 HydrophobicContact CB-CB 3.75Å; A309-H397 VanDerWaalsContact CB-O 3.3Å; A309-H397 WeakPolarHBondContact CB-O 3.34Å; A309-F399 HydrophobicContact CB-CB 4.06Å
310	V	94.9	Very high	96.8	Very high	41 Å²	41	51 Å²	51	25%	0.248	27%	0.265	C	S	.	.	H	α-helix	trans	-68.9	-38.6	172.8	173.4	0	0	0	0	111.9	E306 E308 A313 R314	E306-V310 WeakPolarHBondContact O-CB 3.48Å; E306-V310 VanDerWaalsContact O-CG2 3.31Å; E306-V310 WeakPolarHBondContact O-CG2 3.31Å; E306-V310 PolarHBondContact O-N 3.09Å; E308-V310 VanDerWaalsContact C-N 3.32Å; E308-V310 PolarHBondContact O-N 3.04Å; V310-A313 PolarHBondContact O-N 2.91Å; V310-R314 PolarHBondContact O-N 3.37Å
311	H	95.4	Very high	96.9	Very high	61 Å²	61	50.9 Å²	50.9	28%	0.282	26%	0.26	S	S	.	.	H	α-helix	trans	-65	-47.9	176.3	-160.3	173.7	0	0	0	111.1	Y239 G307 E308 A313 R314 D315	Y239-H311 HydrophobicContact CE1-CB 4.34Å; Y239-H311 AromaticContact CE1-ND1 4Å; Y239-H311 AromaticContact CZ-ND1 3.88Å; Y239-H311 PolarHBondContact OH-ND1 2.92Å; G307-H311 WeakPolarHBondContact O-CB 3.48Å; G307-H311 PolarHBondContact O-N 3.02Å; E308-H311 PolarHBondContact O-N 3.24Å; H311-A313 VanDerWaalsContact C-N 3.28Å; H311-A313 PolarHBondContact O-N 3.28Å; H311-R314 WeakPolarHBondContact O-CA 3.5Å; H311-R314 WeakPolarHBondContact O-CB 3.45Å; H311-R314 PolarHBondContact O-N 2.97Å; H311-D315 IonicContact CD2-OD1 3.17Å; H311-D315 PolarHBondContact CD2-OD1 3.15Å; H311-D315 IonicContact CD2-OD2 2.81Å; H311-D315 IonicContact NE2-OD1 2.7Å; H311-D315 PolarHBondContact O-N 3.12Å
312	L	97	Very high	96.9	Very high	55 Å²	55	51.4 Å²	51.4	29%	0.288	27%	0.271	S	S	.	.	H	α-helix	trans	-58.3	-37.6	176.5	179.7	64	0	0	0	112.5	L230 L304 E308 R314 F316 F399	L230-L312 HydrophobicContact CD1-CD1 4Å; L230-L312 HydrophobicContact CD1-CD2 3.96Å; L230-L312 HydrophobicContact CD1-CG 4.44Å; L304-L312 HydrophobicContact CD1-CD2 3.97Å; E308-L312 VanDerWaalsContact O-CB 3.29Å; E308-L312 WeakPolarHBondContact O-CB 3.41Å; E308-L312 PolarHBondContact O-N 3.33Å; L312-R314 VanDerWaalsContact C-N 3.32Å; L312-F316 VanDerWaalsContact O-CB 3.31Å; L312-F316 WeakPolarHBondContact O-CB 3.43Å; L312-F316 PolarHBondContact O-N 3.2Å; L312-F399 HydrophobicContact CB-CD2 4.32Å; L312-F399 HydrophobicContact CD2-CD2 4.11Å; L312-F399 HydrophobicContact CD2-CE2 3.99Å; L312-F399 HydrophobicContact CG-CD2 4.06Å; L312-F399 HydrophobicContact CG-CE2 3.82Å
313	A	97.5	Very high	97	Very high	1 Å²	1	57.8 Å²	57.8	1%	0.008	30%	0.3	C	S	.	.	H	α-helix	trans	-66.5	-35.3	175	0	0	0	0	0	112.5	A309 V310 H311 A317 F399 Q402	A309-A313 WeakPolarHBondContact O-CB 3.32Å; A309-A313 PolarHBondContact O-N 3.46Å; A309-A313 VanDerWaalsContact O-N 3.09Å; V310-A313 PolarHBondContact O-N 2.91Å; H311-A313 VanDerWaalsContact C-N 3.28Å; H311-A313 PolarHBondContact O-N 3.28Å; A313-A317 WeakPolarHBondContact O-CB 3.35Å; A313-A317 PolarHBondContact O-N 2.81Å; A313-F399 HydrophobicContact CB-CD2 3.75Å; A313-F399 HydrophobicContact CB-CE2 4.33Å; A313-Q402 HydrophobicContact CB-CB 3.64Å
314	R	96.9	Very high	97.1	Very high	151 Å²	151	59.3 Å²	59.3	57%	0.57	30%	0.3	S	S	*	.	H	α-helix	trans	-70.4	-43.3	176.9	-158.2	-170.5	-57.6	143.6	-0.1	111.5	V310 H311 L312 F316 A317 Y318	V310-R314 PolarHBondContact O-N 3.37Å; H311-R314 WeakPolarHBondContact O-CA 3.5Å; H311-R314 WeakPolarHBondContact O-CB 3.45Å; H311-R314 PolarHBondContact O-N 2.97Å; L312-R314 VanDerWaalsContact C-N 3.32Å; R314-F316 VanDerWaalsContact C-N 3.33Å; R314-A317 PolarHBondContact O-N 2.92Å; R314-Y318 PolarHBondContact O-N 2.91Å
315	D	97.1	Very high	97.2	Very high	81 Å²	81	62.4 Å²	62.4	43%	0.433	32%	0.321	S	S	.	.	H	α-helix	trans	-62.8	-41.8	174.7	-64.3	-9.4	0	0	0	111	H311 Y318 V319	H311-D315 IonicContact CD2-OD1 3.17Å; H311-D315 PolarHBondContact CD2-OD1 3.15Å; H311-D315 IonicContact CD2-OD2 2.81Å; H311-D315 IonicContact NE2-OD1 2.7Å; H311-D315 PolarHBondContact O-N 3.12Å; D315-Y318 PolarHBondContact O-N 3.42Å; D315-V319 WeakPolarHBondContact O-CG2 3.4Å; D315-V319 PolarHBondContact O-N 3.32Å
316	F	98.3	Very high	97.2	Very high	83 Å²	83	63.2 Å²	63.2	36%	0.364	33%	0.327	S	S	.	.	H	α-helix	trans	-62.8	-42.4	174.4	-178.2	-105.3	0	0	0	112.1	L312 R314 V319 C320 A403 A406	L312-F316 VanDerWaalsContact O-CB 3.31Å; L312-F316 WeakPolarHBondContact O-CB 3.43Å; L312-F316 PolarHBondContact O-N 3.2Å; R314-F316 VanDerWaalsContact C-N 3.33Å; F316-V319 PolarHBondContact O-N 3.07Å; F316-C320 WeakPolarHBondContact O-CB 3.29Å; F316-C320 PolarHBondContact O-N 3.42Å; F316-C320 PolarHBondContact O-SG 3.1Å; F316-A403 HydrophobicContact CD1-CB 4.06Å; F316-A403 HydrophobicContact CE1-CB 4.27Å; F316-A406 HydrophobicContact CD1-CB 3.88Å; F316-A406 HydrophobicContact CE1-CB 4.05Å
317	A	98.4	Very high	97.2	Very high	36 Å²	36	68.3 Å²	68.3	30%	0.298	35%	0.349	S	S	.	.	H	α-helix	trans	-61	-44.6	174.8	0	0	0	0	0	112.3	A313 R314 C320 E321 A406	A313-A317 WeakPolarHBondContact O-CB 3.35Å; A313-A317 PolarHBondContact O-N 2.81Å; R314-A317 PolarHBondContact O-N 2.92Å; A317-C320 WeakPolarHBondContact O-CB 3.28Å; A317-C320 PolarHBondContact O-N 2.87Å; A317-E321 PolarHBondContact O-N 3.47Å; A317-A406 HydrophobicContact CB-CB 3.82Å
318	Y	98.4	Very high	97.3	Very high	157 Å²	157	69.8 Å²	69.8	62%	0.616	36%	0.357	S	S	*	.	H	α-helix	trans	-58.7	-47.2	175.1	173.8	-94	0	0	0	112	R314 D315 C320 E321 A322	R314-Y318 PolarHBondContact O-N 2.91Å; D315-Y318 PolarHBondContact O-N 3.42Å; Y318-C320 VanDerWaalsContact C-N 3.34Å; Y318-C320 PolarHBondContact O-N 3.45Å; Y318-E321 PolarHBondContact O-N 3.27Å; Y318-E321 VanDerWaalsContact O-N 3.14Å; Y318-A322 HydrophobicContact CE1-CB 4.25Å; Y318-A322 HydrophobicContact CE2-CB 4.49Å; Y318-A322 WeakPolarHBondContact O-CB 3.43Å; Y318-A322 PolarHBondContact O-N 3.12Å
319	V	98.3	Very high	97.4	Very high	75 Å²	75	71.4 Å²	71.4	46%	0.455	37%	0.368	S	S	.	.	H	α-helix	trans	-65	-37.5	177.3	174.1	0	0	0	0	111.6	D315 F316 E321 E323	D315-V319 WeakPolarHBondContact O-CG2 3.4Å; D315-V319 PolarHBondContact O-N 3.32Å; F316-V319 PolarHBondContact O-N 3.07Å; V319-E321 VanDerWaalsContact C-N 3.27Å; V319-E321 PolarHBondContact O-N 2.98Å; V319-E323 HydrophobicContact CG1-CB 4.14Å; V319-E323 HydrophobicContact CG1-CG 4.16Å; V319-E323 WeakPolarHBondContact O-CB 3.4Å; V319-E323 PolarHBondContact O-N 3.31Å
320	C	98.4	Very high	97.4	Very high	18 Å²	18	71.4 Å²	71.4	12%	0.122	37%	0.368	C	S	.	.	H	α-helix	trans	-63.7	-28.4	173.3	-80	0	0	0	0	113.7	F316 A317 Y318 F324 A410	F316-C320 WeakPolarHBondContact O-CB 3.29Å; F316-C320 PolarHBondContact O-N 3.42Å; F316-C320 PolarHBondContact O-SG 3.1Å; A317-C320 WeakPolarHBondContact O-CB 3.28Å; A317-C320 PolarHBondContact O-N 2.87Å; Y318-C320 VanDerWaalsContact C-N 3.34Å; Y318-C320 PolarHBondContact O-N 3.45Å; C320-F324 WeakPolarHBondContact O-CB 3.31Å; C320-A410 HydrophobicContact CB-CB 4.35Å
321	E	97	Very high	97.4	Very high	150 Å²	150	73 Å²	73	70%	0.701	38%	0.375	S	S	*	.	H	α-helix	trans	-87	-44.5	177.8	-175.7	166.4	-158.1	0	0	112.5	A317 Y318 V319	A317-E321 PolarHBondContact O-N 3.47Å; Y318-E321 PolarHBondContact O-N 3.27Å; Y318-E321 VanDerWaalsContact O-N 3.14Å; V319-E321 VanDerWaalsContact C-N 3.27Å; V319-E321 PolarHBondContact O-N 2.98Å
322	A	97.6	Very high	97.5	Very high	54 Å²	54	78.1 Å²	78.1	45%	0.446	39%	0.393	S	S	.	.	H	α-helix	trans	-81.1	-40.5	-174.4	0	0	0	0	0	114	Y318	Y318-A322 HydrophobicContact CE1-CB 4.25Å; Y318-A322 HydrophobicContact CE2-CB 4.49Å; Y318-A322 WeakPolarHBondContact O-CB 3.43Å; Y318-A322 PolarHBondContact O-N 3.12Å
323	E	97.7	Very high	97.4	Very high	139 Å²	139	78.7 Å²	78.7	65%	0.65	40%	0.396	S	S	*	.	T	Hydrogen-bonded Turn	trans	-107.8	-17.6	-167.6	-57.6	-64.5	152.2	0	0	113.7	V319 P325	V319-E323 HydrophobicContact CG1-CB 4.14Å; V319-E323 HydrophobicContact CG1-CG 4.16Å; V319-E323 WeakPolarHBondContact O-CB 3.4Å; V319-E323 PolarHBondContact O-N 3.31Å; E323-P325 WeakPolarHBondContact O-CD 3.5Å
324	F	97.8	Very high	97.1	Very high	86 Å²	86	78.8 Å²	78.8	38%	0.377	40%	0.397	S	S	.	.			trans	-73.1	123.3	-176.6	-173	-100.9	0	0	0	111.5	C320 S326 A410	C320-F324 WeakPolarHBondContact O-CB 3.31Å; F324-S326 WeakPolarHBondContact CD1-OG 3.36Å; F324-S326 PolarHBondContact O-N 2.89Å; F324-A410 HydrophobicContact CB-CB 4.44Å; F324-A410 HydrophobicContact CD1-CB 3.82Å; F324-A410 HydrophobicContact CE1-CB 4.24Å; F324-A410 HydrophobicContact CG-CB 4.05Å
325	P	98	Very high	96.9	Very high	73 Å²	73	79.1 Å²	79.1	47%	0.474	40%	0.398	S	S	.	.			trans	-81.5	53.2	-168.4	34.3	-38.1	0	0	0	113.4	E323 K327 A328 V329	E323-P325 WeakPolarHBondContact O-CD 3.5Å; P325-K327 PolarHBondContact O-N 2.9Å; P325-K327 VanDerWaalsContact O-N 3.09Å; P325-A328 HydrophobicContact CB-CB 4.33Å; P325-A328 PolarHBondContact O-N 2.82Å; P325-V329 HydrophobicContact CG-CG2 4.16Å; P325-V329 WeakPolarHBondContact O-CG2 3.42Å; P325-V329 PolarHBondContact O-N 3.48Å
326	S	97.9	Very high	96.5	Very high	17 Å²	17	79.9 Å²	79.9	12%	0.119	41%	0.407	C	S	.	.	H	α-helix	trans	-43.7	-47	-175.9	-67.4	0	0	0	0	113.4	F324 A330 N413	F324-S326 WeakPolarHBondContact CD1-OG 3.36Å; F324-S326 PolarHBondContact O-N 2.89Å; S326-A330 VanDerWaalsContact O-CB 3.29Å; S326-A330 WeakPolarHBondContact O-CB 3.45Å; S326-A330 PolarHBondContact O-N 2.92Å; S326-N413 WeakPolarHBondContact OG-CB 3.23Å
327	K	97.1	Very high	96.1	Very high	119 Å²	119	78.4 Å²	78.4	52%	0.517	40%	0.401	S	S	.	.	H	α-helix	trans	-68.4	-46.2	-178.9	-177.8	176.5	176	-173.3	0	113.3	P325 V329 A330 D331 E417	P325-K327 PolarHBondContact O-N 2.9Å; P325-K327 VanDerWaalsContact O-N 3.09Å; K327-V329 VanDerWaalsContact C-N 3.3Å; K327-V329 PolarHBondContact O-N 3.33Å; K327-A330 WeakPolarHBondContact O-CB 3.41Å; K327-A330 PolarHBondContact O-N 3.22Å; K327-D331 PolarHBondContact O-N 3.16Å; K327-E417 HydrophobicContact CB-CG 4.02Å; K327-E417 WeakPolarHBondContact CG-OE2 3.29Å
328	A	97.7	Very high	95.3	Very high	61 Å²	61	80 Å²	80	50%	0.504	40%	0.404	S	S	.	.	H	α-helix	trans	-66.3	-36.2	179	0	0	0	0	0	111.6	P325 Y332	P325-A328 HydrophobicContact CB-CB 4.33Å; P325-A328 PolarHBondContact O-N 2.82Å; A328-Y332 WeakPolarHBondContact O-CB 3.28Å; A328-Y332 PolarHBondContact O-N 3.23Å
329	V	97.9	Very high	94.2	Very high	42 Å²	42	75.9 Å²	75.9	26%	0.255	41%	0.41	S	S	.	.	H	α-helix	trans	-64.3	-42.9	172	175.6	0	0	0	0	110.7	P325 K327 Y332 L333 Y414	P325-V329 HydrophobicContact CG-CG2 4.16Å; P325-V329 WeakPolarHBondContact O-CG2 3.42Å; P325-V329 PolarHBondContact O-N 3.48Å; K327-V329 VanDerWaalsContact C-N 3.3Å; K327-V329 PolarHBondContact O-N 3.33Å; V329-Y332 PolarHBondContact O-N 3.42Å; V329-L333 HydrophobicContact CG1-CD1 3.77Å; V329-L333 HydrophobicContact CG1-CG 4.44Å; V329-L333 WeakPolarHBondContact O-CB 2.99Å; V329-L333 WeakPolarHBondContact O-CG 3.33Å; V329-L333 PolarHBondContact O-N 3.07Å; V329-Y414 HydrophobicContact CB-CD2 4.32Å; V329-Y414 HydrophobicContact CG1-CD2 3.73Å; V329-Y414 HydrophobicContact CG1-CE2 4.12Å; V329-Y414 HydrophobicContact CG1-CG 4.25Å
330	A	97.2	Very high	93.4	Very high	0 Å²	0	73.4 Å²	73.4	0%	0	40%	0.4	C	S	.	.	H	α-helix	trans	-62.1	-48.9	175.4	0	0	0	0	0	112.6	S326 K327 Y332 L333 T334 Y414 E417 A418	S326-A330 VanDerWaalsContact O-CB 3.29Å; S326-A330 WeakPolarHBondContact O-CB 3.45Å; S326-A330 PolarHBondContact O-N 2.92Å; K327-A330 WeakPolarHBondContact O-CB 3.41Å; K327-A330 PolarHBondContact O-N 3.22Å; A330-Y332 VanDerWaalsContact C-N 3.33Å; A330-Y332 PolarHBondContact O-N 3.49Å; A330-L333 PolarHBondContact O-N 3.01Å; A330-T334 WeakPolarHBondContact O-CB 3.35Å; A330-T334 PolarHBondContact O-N 3.27Å; A330-T334 PolarHBondContact O-OG1 2.83Å; A330-Y414 HydrophobicContact CB-CD2 3.98Å; A330-Y414 HydrophobicContact CB-CE2 4.41Å; A330-E417 HydrophobicContact CB-CB 3.56Å; A330-A418 HydrophobicContact CB-CB 3.97Å
331	D	94.6	Very high	92.6	Very high	74 Å²	74	82.1 Å²	82.1	40%	0.396	43%	0.43	S	S	.	.	H	α-helix	trans	-61	-40.7	177.8	-73.5	-27.4	0	0	0	111.6	K327 R335	K327-D331 PolarHBondContact O-N 3.16Å; D331-R335 WeakPolarHBondContact O-CB 3.2Å; D331-R335 PolarHBondContact O-N 3.36Å
332	Y	96.1	Very high	92.2	Very high	168 Å²	168	81.3 Å²	81.3	66%	0.659	43%	0.43	S	S	*	.	H	α-helix	trans	-66.4	-49.1	177.2	-178.3	-98.5	0	0	0	112.4	A328 V329 A330	A328-Y332 WeakPolarHBondContact O-CB 3.28Å; A328-Y332 PolarHBondContact O-N 3.23Å; V329-Y332 PolarHBondContact O-N 3.42Å; A330-Y332 VanDerWaalsContact C-N 3.33Å; A330-Y332 PolarHBondContact O-N 3.49Å
333	L	95.3	Very high	91.8	Very high	68 Å²	68	83.5 Å²	83.5	36%	0.356	43%	0.432	S	S	.	.	H	α-helix	trans	-78.8	-21.1	-175.8	-65.9	177	0	0	0	113.9	V329 A330 H337 Y414	V329-L333 HydrophobicContact CG1-CD1 3.77Å; V329-L333 HydrophobicContact CG1-CG 4.44Å; V329-L333 WeakPolarHBondContact O-CB 2.99Å; V329-L333 WeakPolarHBondContact O-CG 3.33Å; V329-L333 PolarHBondContact O-N 3.07Å; A330-L333 PolarHBondContact O-N 3.01Å; L333-H337 PolarHBondContact O-CE1 3.4Å; L333-H337 VanDerWaalsContact O-CE1 3.22Å; L333-H337 PolarHBondContact O-ND1 2.99Å; L333-H337 VanDerWaalsContact O-ND1 3.12Å; L333-Y414 HydrophobicContact CB-CE2 4.28Å; L333-Y414 HydrophobicContact CD1-CE2 3.74Å
334	T	92.6	Very high	91.4	Very high	3 Å²	3	77.2 Å²	77.2	2%	0.018	40%	0.402	C	S	.	.	H	α-helix	trans	-82.7	-34.6	177.3	-55.8	0	0	0	0	111.4	A330 P336 H337 M344 A421 I422	A330-T334 WeakPolarHBondContact O-CB 3.35Å; A330-T334 PolarHBondContact O-N 3.27Å; A330-T334 PolarHBondContact O-OG1 2.83Å; T334-P336 VanDerWaalsContact C-CD 3.43Å; T334-P336 VanDerWaalsContact O-N 3.17Å; T334-H337 WeakPolarHBondContact O-CB 3.31Å; T334-H337 PolarHBondContact O-N 3.02Å; T334-H337 PolarHBondContact O-ND1 3.43Å; T334-M344 HydrophobicContact CG2-CE 3.89Å; T334-A421 HydrophobicContact CG2-CB 4.35Å; T334-I422 HydrophobicContact CG2-CD1 4.41Å; T334-I422 HydrophobicContact CG2-CG1 3.75Å
335	R	90.9	Very high	91.1	Very high	158 Å²	158	75.3 Å²	75.3	60%	0.596	40%	0.402	S	S	*	.	G	3₁₀ helix	trans	-46	-45.2	-176	-170.9	-175.7	-51.2	-176.7	3.3	116.1	D331 H337 L338	D331-R335 WeakPolarHBondContact O-CB 3.2Å; D331-R335 PolarHBondContact O-N 3.36Å; R335-H337 PolarHBondContact O-N 3.43Å; R335-L338 PolarHBondContact O-N 3.26Å
336	P	90.3	Very high	90.9	Very high	96 Å²	96	75.9 Å²	75.9	62%	0.623	41%	0.405	S	S	*	.	G	3₁₀ helix	trans	-63.2	-25.8	-178.2	-23.1	35.4	0	0	0	113.8	T334	T334-P336 VanDerWaalsContact C-CD 3.43Å; T334-P336 VanDerWaalsContact O-N 3.17Å
337	H	89	Confident	90.8	Very high	52 Å²	52	76.7 Å²	76.7	24%	0.241	41%	0.405	C	S	.	.	G	3₁₀ helix	trans	-88	-5.7	-174.3	-51.5	88.4	0	0	0	112.8	L333 T334 R335 G339 M344 R347	L333-H337 PolarHBondContact O-CE1 3.4Å; L333-H337 VanDerWaalsContact O-CE1 3.22Å; L333-H337 PolarHBondContact O-ND1 2.99Å; L333-H337 VanDerWaalsContact O-ND1 3.12Å; T334-H337 WeakPolarHBondContact O-CB 3.31Å; T334-H337 PolarHBondContact O-N 3.02Å; T334-H337 PolarHBondContact O-ND1 3.43Å; R335-H337 PolarHBondContact O-N 3.43Å; H337-G339 PolarHBondContact O-N 3.22Å; H337-M344 HydrophobicContact CB-CE 3.43Å; H337-M344 VanDerWaalsContact CB-CE 3.43Å; H337-M344 VanDerWaalsContact O-CE 3.31Å; H337-M344 WeakPolarHBondContact O-CE 3.17Å; H337-M344 WeakPolarHBondContact O-CG 3.44Å; H337-R347 HydrophobicContact CB-CB 4.3Å; H337-R347 HydrophobicContact CB-CG 4.31Å
338	L	81.8	Confident	90.7	Very high	69 Å²	69	73.8 Å²	73.8	36%	0.361	39%	0.392	S	S	.	.	G	3₁₀ helix	trans	-70.8	-12.9	-176.3	-68.4	171.5	0	0	0	113.2	R335 G340 M344	R335-L338 PolarHBondContact O-N 3.26Å; L338-G340 VanDerWaalsContact C-N 3.34Å; L338-G340 PolarHBondContact O-N 3.44Å; L338-M344 HydrophobicContact CD2-CE 3.82Å; L338-M344 HydrophobicContact CD2-SD 3.91Å; L338-M344 HydrophobicContact CG-CE 4.23Å
339	G	76	Confident	90.7	Very high	72 Å²	72	74.7 Å²	74.7	74%	0.742	40%	0.395	S	S	*	.	G	3₁₀ helix	trans	-76.4	-11.3	-176	0	0	0	0	0	115.5	H337	H337-G339 PolarHBondContact O-N 3.22Å
340	G	80.6	Confident	90.6	Very high	23 Å²	23	78.2 Å²	78.2	24%	0.237	41%	0.41	C	S	.	.			trans	-150	132.5	-177.9	0	0	0	0	0	114.2	L338 N342 E343 M344	L338-G340 VanDerWaalsContact C-N 3.34Å; L338-G340 PolarHBondContact O-N 3.44Å; G340-N342 PolarHBondContact O-N 3.33Å; G340-E343 WeakPolarHBondContact O-CB 3.28Å; G340-E343 PolarHBondContact O-N 3.09Å; G340-M344 PolarHBondContact O-N 3.42Å
341	R	82.6	Confident	90.6	Very high	201 Å²	201	78.5 Å²	78.5	76%	0.758	41%	0.412	S	S	*	.	H	α-helix	trans	-56.2	-35.8	177.5	-173.1	175.2	-177.6	160.2	2.6	113.1	A345 Y426	R341-A345 WeakPolarHBondContact O-CB 3.48Å; R341-A345 PolarHBondContact O-N 3.41Å; R341-Y426 HydrophobicContact CG-CE1 4.49Å
342	N	86.9	Confident	90.8	Very high	132 Å²	132	78.9 Å²	78.9	71%	0.706	41%	0.413	S	S	*	.	H	α-helix	trans	-73.9	-32.6	177.3	-67	-18.3	0	0	0	112.5	G340 T346	G340-N342 PolarHBondContact O-N 3.33Å; N342-T346 WeakPolarHBondContact O-CB 3.43Å; N342-T346 PolarHBondContact O-N 3.15Å; N342-T346 PolarHBondContact O-OG1 2.71Å
343	E	89.5	Confident	90.9	Very high	101 Å²	101	73.6 Å²	73.6	47%	0.472	40%	0.404	S	S	.	.	H	α-helix	trans	-70.8	-46.1	175.7	-60.1	179	168.4	0	0	110	G340 A345 T346 R347	G340-E343 WeakPolarHBondContact O-CB 3.28Å; G340-E343 PolarHBondContact O-N 3.09Å; E343-A345 PolarHBondContact O-N 2.83Å; E343-T346 PolarHBondContact O-N 2.93Å; E343-R347 WeakPolarHBondContact O-CB 3.3Å; E343-R347 PolarHBondContact O-N 3.48Å
344	M	90	Very high	91.1	Very high	6 Å²	6	72.3 Å²	72.3	3%	0.03	40%	0.403	C	S	.	.	H	α-helix	trans	-53.6	-48.5	169.6	-83.2	-74.3	103.9	0	0	112.7	T334 H337 L338 G340 R347 K348 I422	T334-M344 HydrophobicContact CG2-CE 3.89Å; H337-M344 HydrophobicContact CB-CE 3.43Å; H337-M344 VanDerWaalsContact CB-CE 3.43Å; H337-M344 VanDerWaalsContact O-CE 3.31Å; H337-M344 WeakPolarHBondContact O-CE 3.17Å; H337-M344 WeakPolarHBondContact O-CG 3.44Å; L338-M344 HydrophobicContact CD2-CE 3.82Å; L338-M344 HydrophobicContact CD2-SD 3.91Å; L338-M344 HydrophobicContact CG-CE 4.23Å; G340-M344 PolarHBondContact O-N 3.42Å; M344-R347 PolarHBondContact O-N 2.74Å; M344-K348 WeakPolarHBondContact O-CB 3.47Å; M344-K348 PolarHBondContact O-N 2.85Å; M344-I422 HydrophobicContact CE-CG1 4.05Å; M344-I422 HydrophobicContact SD-CB 4.23Å; M344-I422 HydrophobicContact SD-CG1 3.8Å; M344-I422 HydrophobicContact SD-CG2 3.95Å
345	A	92.4	Very high	91.3	Very high	46 Å²	46	74.8 Å²	74.8	38%	0.38	42%	0.415	S	S	.	.	H	α-helix	trans	-64.6	-44.3	179.6	0	0	0	0	0	112.3	R341 E343 R347 K348 S349 Y426	R341-A345 WeakPolarHBondContact O-CB 3.48Å; R341-A345 PolarHBondContact O-N 3.41Å; E343-A345 PolarHBondContact O-N 2.83Å; A345-R347 VanDerWaalsContact C-N 3.35Å; A345-K348 PolarHBondContact O-N 3.46Å; A345-S349 PolarHBondContact O-N 2.64Å; A345-Y426 PolarHBondContact N-OH 3.25Å
346	T	93.4	Very high	91.6	Very high	86 Å²	86	71.8 Å²	71.8	53%	0.528	41%	0.408	S	S	.	.	H	α-helix	trans	-60.2	-46.4	174.7	-56.8	0	0	0	0	110.7	N342 E343 K348 S349 M350	N342-T346 WeakPolarHBondContact O-CB 3.43Å; N342-T346 PolarHBondContact O-N 3.15Å; N342-T346 PolarHBondContact O-OG1 2.71Å; E343-T346 PolarHBondContact O-N 2.93Å; T346-K348 PolarHBondContact O-N 2.82Å; T346-S349 WeakPolarHBondContact O-CB 3.48Å; T346-S349 PolarHBondContact O-N 2.72Å; T346-M350 HydrophobicContact CG2-SD 4.27Å; T346-M350 WeakPolarHBondContact O-CG 3.46Å; T346-M350 PolarHBondContact O-N 2.85Å
347	R	94.8	Very high	92	Very high	33 Å²	33	71.6 Å²	71.6	13%	0.125	41%	0.405	C	S	.	.	H	α-helix	trans	-61	-44.1	178.3	-179.7	59.7	176.9	-174.2	2.4	112	H337 E343 M344 A345 M350 L351 Y414 I422	H337-R347 HydrophobicContact CB-CB 4.3Å; H337-R347 HydrophobicContact CB-CG 4.31Å; E343-R347 WeakPolarHBondContact O-CB 3.3Å; E343-R347 PolarHBondContact O-N 3.48Å; M344-R347 PolarHBondContact O-N 2.74Å; A345-R347 VanDerWaalsContact C-N 3.35Å; R347-M350 PolarHBondContact O-N 2.86Å; R347-L351 HydrophobicContact CG-CD1 4.12Å; R347-L351 WeakPolarHBondContact O-CG 3.41Å; R347-L351 PolarHBondContact O-N 2.74Å; R347-Y414 PolarHBondContact NH2-OH 2.93Å; R347-I422 HydrophobicContact CB-CD1 4.48Å; R347-I422 HydrophobicContact CG-CD1 3.91Å
348	K	95.6	Very high	92.5	Very high	58 Å²	58	70.2 Å²	70.2	25%	0.252	40%	0.4	S	S	.	.	H	α-helix	trans	-60	-45	175.6	-173.7	166.1	-175.9	166.7	0	111.5	M344 A345 T346 L351 L352 L419 I422 D423	M344-K348 WeakPolarHBondContact O-CB 3.47Å; M344-K348 PolarHBondContact O-N 2.85Å; A345-K348 PolarHBondContact O-N 3.46Å; T346-K348 PolarHBondContact O-N 2.82Å; K348-L351 PolarHBondContact O-N 2.81Å; K348-L352 HydrophobicContact CG-CD1 4.13Å; K348-L352 WeakPolarHBondContact O-CG 3.44Å; K348-L352 PolarHBondContact O-N 2.93Å; K348-L419 HydrophobicContact CG-CD2 3.89Å; K348-I422 HydrophobicContact CB-CD1 4.33Å; K348-I422 HydrophobicContact CB-CG2 4.3Å; K348-I422 HydrophobicContact CD-CG2 4.2Å; K348-D423 VanDerWaalsContact NZ-CG 3.29Å; K348-D423 IonicContact NZ-OD1 2.74Å; K348-D423 PolarHBondContact NZ-OD1 3.29Å; K348-D423 IonicContact NZ-OD2 3.47Å; K348-D423 PolarHBondContact NZ-OD2 2.98Å; K348-D423 VanDerWaalsContact NZ-OD2 3.14Å
349	S	96.5	Very high	93.2	Very high	80 Å²	80	71.9 Å²	71.9	56%	0.559	41%	0.405	S	S	*	.	H	α-helix	trans	-59.5	-47.5	176.3	-172.7	0	0	0	0	112.2	A345 T346 L351 L352 A353	A345-S349 PolarHBondContact O-N 2.64Å; T346-S349 WeakPolarHBondContact O-CB 3.48Å; T346-S349 PolarHBondContact O-N 2.72Å; S349-L351 VanDerWaalsContact C-N 3.34Å; S349-L351 PolarHBondContact O-N 2.79Å; S349-L352 PolarHBondContact O-N 3.38Å; S349-A353 WeakPolarHBondContact O-CB 3.34Å; S349-A353 PolarHBondContact O-N 3.05Å
350	M	96.9	Very high	94.3	Very high	117 Å²	117	73.6 Å²	73.6	58%	0.576	39%	0.393	S	S	*	.	H	α-helix	trans	-60.8	-40.2	176.7	-67.7	173.9	72.5	0	0	112.9	T346 R347 A354	T346-M350 HydrophobicContact CG2-SD 4.27Å; T346-M350 WeakPolarHBondContact O-CG 3.46Å; T346-M350 PolarHBondContact O-N 2.85Å; R347-M350 PolarHBondContact O-N 2.86Å; M350-A354 WeakPolarHBondContact O-CB 3.16Å; M350-A354 PolarHBondContact O-N 2.77Å
351	L	97.7	Very high	95.1	Very high	5 Å²	5	76.9 Å²	76.9	3%	0.026	40%	0.401	C	S	.	.	H	α-helix	trans	-66.4	-43.6	178.4	-75.1	168.5	0	0	0	112.1	R347 K348 S349 A354 Q355 I415 A418 L419 I422	R347-L351 HydrophobicContact CG-CD1 4.12Å; R347-L351 WeakPolarHBondContact O-CG 3.41Å; R347-L351 PolarHBondContact O-N 2.74Å; K348-L351 PolarHBondContact O-N 2.81Å; S349-L351 VanDerWaalsContact C-N 3.34Å; S349-L351 PolarHBondContact O-N 2.79Å; L351-A354 PolarHBondContact O-N 3.47Å; L351-Q355 WeakPolarHBondContact O-CB 3.18Å; L351-Q355 PolarHBondContact O-N 3.21Å; L351-I415 HydrophobicContact CB-CG2 4.17Å; L351-I415 HydrophobicContact CD2-CG1 4.13Å; L351-I415 HydrophobicContact CD2-CG2 4.24Å; L351-I415 WeakPolarHBondContact O-CG2 3.5Å; L351-A418 HydrophobicContact CD1-CB 3.74Å; L351-A418 HydrophobicContact CD2-CB 4.12Å; L351-L419 HydrophobicContact CB-CD2 3.88Å; L351-L419 HydrophobicContact CB-CG 4.27Å; L351-L419 HydrophobicContact CD1-CD2 4.28Å; L351-I422 HydrophobicContact CD1-CD1 3.52Å
352	L	98.1	Very high	95.8	Very high	82 Å²	82	67.8 Å²	67.8	43%	0.429	37%	0.368	S	S	.	.	H	α-helix	trans	-64.6	-42.6	176.4	-69.2	169.8	0	0	0	111.9	K348 S349 Q355 Q356 L419	K348-L352 HydrophobicContact CG-CD1 4.13Å; K348-L352 WeakPolarHBondContact O-CG 3.44Å; K348-L352 PolarHBondContact O-N 2.93Å; S349-L352 PolarHBondContact O-N 3.38Å; L352-Q355 WeakPolarHBondContact O-CB 3.11Å; L352-Q355 PolarHBondContact O-N 2.97Å; L352-Q356 PolarHBondContact O-N 2.75Å; L352-Q356 VanDerWaalsContact O-N 3.09Å; L352-L419 HydrophobicContact CD2-CD1 3.84Å; L352-L419 HydrophobicContact CD2-CD2 4.13Å; L352-L419 HydrophobicContact CG-CD2 4.09Å
353	A	98.4	Very high	96.3	Very high	57 Å²	57	64.7 Å²	64.7	47%	0.471	35%	0.352	S	S	.	.	H	α-helix	trans	-61.5	-44.5	174.6	0	0	0	0	0	111.9	S349 Q355 Q356 V357	S349-A353 WeakPolarHBondContact O-CB 3.34Å; S349-A353 PolarHBondContact O-N 3.05Å; A353-Q355 VanDerWaalsContact C-N 3.34Å; A353-Q355 PolarHBondContact O-N 3.43Å; A353-Q356 PolarHBondContact O-N 2.84Å; A353-V357 WeakPolarHBondContact O-CG2 3.37Å; A353-V357 PolarHBondContact O-N 3.39Å; A353-V357 VanDerWaalsContact O-N 3.07Å
354	A	98.4	Very high	96.7	Very high	41 Å²	41	62.8 Å²	62.8	34%	0.339	34%	0.344	S	S	.	.	H	α-helix	trans	-62.8	-38.6	175.6	0	0	0	0	0	112.4	M350 L351 Q356 V357 C358 I415	M350-A354 WeakPolarHBondContact O-CB 3.16Å; M350-A354 PolarHBondContact O-N 2.77Å; L351-A354 PolarHBondContact O-N 3.47Å; A354-Q356 VanDerWaalsContact C-N 3.35Å; A354-Q356 PolarHBondContact O-N 3.17Å; A354-V357 PolarHBondContact O-N 2.93Å; A354-C358 WeakPolarHBondContact O-CB 3.5Å; A354-C358 PolarHBondContact O-N 2.9Å; A354-C358 PolarHBondContact O-SG 2.86Å; A354-I415 HydrophobicContact CB-CD1 3.94Å
355	Q	97.8	Very high	97	Very high	56 Å²	56	63.2 Å²	63.2	26%	0.262	35%	0.346	S	S	.	.	H	α-helix	trans	-60.4	-44.6	176.4	-164.5	175.8	31.9	0	0	111.7	L351 L352 A353 C358 K359 I415	L351-Q355 WeakPolarHBondContact O-CB 3.18Å; L351-Q355 PolarHBondContact O-N 3.21Å; L352-Q355 WeakPolarHBondContact O-CB 3.11Å; L352-Q355 PolarHBondContact O-N 2.97Å; A353-Q355 VanDerWaalsContact C-N 3.34Å; A353-Q355 PolarHBondContact O-N 3.43Å; Q355-C358 PolarHBondContact O-N 3.23Å; Q355-K359 PolarHBondContact O-N 2.82Å; Q355-I415 HydrophobicContact CB-CG2 3.99Å; Q355-I415 HydrophobicContact CG-CG2 4.33Å
356	Q	98.1	Very high	97.1	Very high	95 Å²	95	66.4 Å²	66.4	44%	0.444	35%	0.353	S	S	.	.	H	α-helix	trans	-65.5	-46.5	179.1	-179	58.5	24.6	0	0	111.7	L352 A353 A354 C358 K359 E360	L352-Q356 PolarHBondContact O-N 2.75Å; L352-Q356 VanDerWaalsContact O-N 3.09Å; A353-Q356 PolarHBondContact O-N 2.84Å; A354-Q356 VanDerWaalsContact C-N 3.35Å; A354-Q356 PolarHBondContact O-N 3.17Å; Q356-C358 VanDerWaalsContact C-N 3.33Å; Q356-C358 PolarHBondContact O-N 2.7Å; Q356-K359 WeakPolarHBondContact O-CB 3.22Å; Q356-K359 PolarHBondContact O-N 2.88Å; Q356-K359 VanDerWaalsContact O-N 3.11Å; Q356-E360 WeakPolarHBondContact CG-OE1 3.25Å; Q356-E360 PolarHBondContact NE2-OE1 3.07Å; Q356-E360 WeakPolarHBondContact O-CG 3.17Å; Q356-E360 PolarHBondContact O-N 3.22Å
357	V	98.4	Very high	97.2	Very high	92 Å²	92	66 Å²	66	56%	0.558	35%	0.345	S	S	*	.	H	α-helix	trans	-60.3	-41.8	175.4	173	0	0	0	0	111.7	A353 A354 K359 F361	A353-V357 WeakPolarHBondContact O-CG2 3.37Å; A353-V357 PolarHBondContact O-N 3.39Å; A353-V357 VanDerWaalsContact O-N 3.07Å; A354-V357 PolarHBondContact O-N 2.93Å; V357-K359 VanDerWaalsContact C-N 3.31Å; V357-K359 PolarHBondContact O-N 2.77Å; V357-F361 WeakPolarHBondContact O-CB 3.38Å; V357-F361 PolarHBondContact O-N 3.3Å; V357-F361 VanDerWaalsContact O-N 3.1Å
358	C	98.4	Very high	97.2	Very high	22 Å²	22	65.7 Å²	65.7	15%	0.149	35%	0.346	C	S	.	.	H	α-helix	trans	-59.5	-43.4	174.9	-70	0	0	0	0	111.4	A354 Q355 Q356 T362 V408 Q412	A354-C358 WeakPolarHBondContact O-CB 3.5Å; A354-C358 PolarHBondContact O-N 2.9Å; A354-C358 PolarHBondContact O-SG 2.86Å; Q355-C358 PolarHBondContact O-N 3.23Å; Q356-C358 VanDerWaalsContact C-N 3.33Å; Q356-C358 PolarHBondContact O-N 2.7Å; C358-T362 PolarHBondContact O-N 3.39Å; C358-T362 PolarHBondContact O-OG1 3.38Å; C358-T362 VanDerWaalsContact O-OG1 3.11Å; C358-V408 HydrophobicContact CB-CG1 3.62Å; C358-Q412 HydrophobicContact CB-CG 3.7Å
359	K	97.6	Very high	97.1	Very high	105 Å²	105	66.1 Å²	66.1	46%	0.457	35%	0.346	S	S	.	.	H	α-helix	trans	-64.4	-51.7	179.9	-177.1	-175.4	173.9	-172.8	0	111.7	Q355 Q356 V357 F361 T362 D363	Q355-K359 PolarHBondContact O-N 2.82Å; Q356-K359 WeakPolarHBondContact O-CB 3.22Å; Q356-K359 PolarHBondContact O-N 2.88Å; Q356-K359 VanDerWaalsContact O-N 3.11Å; V357-K359 VanDerWaalsContact C-N 3.31Å; V357-K359 PolarHBondContact O-N 2.77Å; K359-F361 PolarHBondContact O-N 3.46Å; K359-T362 WeakPolarHBondContact CA-OG1 3.26Å; K359-T362 PolarHBondContact O-N 3.1Å; K359-T362 VanDerWaalsContact O-N 3.15Å; K359-T362 PolarHBondContact O-OG1 3.32Å; K359-D363 WeakPolarHBondContact CE-OD2 3.36Å; K359-D363 WeakPolarHBondContact CG-OD2 3.42Å; K359-D363 WeakPolarHBondContact O-CB 3.46Å; K359-D363 VanDerWaalsContact O-CG 3.22Å; K359-D363 PolarHBondContact O-N 3.46Å
360	E	97.7	Very high	96.9	Very high	107 Å²	107	62.9 Å²	62.9	50%	0.5	32%	0.323	S	S	.	.	H	α-helix	trans	-55.4	-41.5	178.2	-72.3	170.5	-166.2	0	0	111.9	Q356 D363 L364	Q356-E360 WeakPolarHBondContact CG-OE1 3.25Å; Q356-E360 PolarHBondContact NE2-OE1 3.07Å; Q356-E360 WeakPolarHBondContact O-CG 3.17Å; Q356-E360 PolarHBondContact O-N 3.22Å; E360-D363 PolarHBondContact O-N 2.82Å; E360-L364 PolarHBondContact O-N 2.94Å; E360-L364 VanDerWaalsContact O-N 3.07Å
361	F	98	Very high	96.3	Very high	93 Å²	93	59.4 Å²	59.4	41%	0.408	31%	0.309	S	S	.	.	H	α-helix	trans	-67.6	-43.5	177.3	-177.1	-123.5	0	0	0	112.8	V357 K359 L364 L365 I404 V408	V357-F361 WeakPolarHBondContact O-CB 3.38Å; V357-F361 PolarHBondContact O-N 3.3Å; V357-F361 VanDerWaalsContact O-N 3.1Å; K359-F361 PolarHBondContact O-N 3.46Å; F361-L364 PolarHBondContact O-N 3.17Å; F361-L365 HydrophobicContact CD1-CD1 4.49Å; F361-L365 HydrophobicContact CE1-CD1 4.06Å; F361-L365 HydrophobicContact CE2-CD1 4.48Å; F361-L365 HydrophobicContact CZ-CD1 4.05Å; F361-L365 WeakPolarHBondContact O-CG 3.45Å; F361-L365 PolarHBondContact O-N 2.91Å; F361-I404 HydrophobicContact CE1-CG2 3.55Å; F361-I404 HydrophobicContact CZ-CG2 4.05Å; F361-V408 HydrophobicContact CD1-CG2 4.21Å; F361-V408 HydrophobicContact CE1-CG2 4.37Å
362	T	97.7	Very high	95.5	Very high	10 Å²	10	60.8 Å²	60.8	6%	0.061	32%	0.317	C	S	.	.	H	α-helix	trans	-66.7	-37	174.6	48.8	0	0	0	0	112.5	C358 K359 L364 L365 H366 V408	C358-T362 PolarHBondContact O-N 3.39Å; C358-T362 PolarHBondContact O-OG1 3.38Å; C358-T362 VanDerWaalsContact O-OG1 3.11Å; K359-T362 WeakPolarHBondContact CA-OG1 3.26Å; K359-T362 PolarHBondContact O-N 3.1Å; K359-T362 VanDerWaalsContact O-N 3.15Å; K359-T362 PolarHBondContact O-OG1 3.32Å; T362-L364 VanDerWaalsContact C-N 3.29Å; T362-L364 PolarHBondContact O-N 2.59Å; T362-L365 PolarHBondContact O-N 3.28Å; T362-L365 VanDerWaalsContact O-N 3.12Å; T362-H366 VanDerWaalsContact O-CG 3.31Å; T362-H366 PolarHBondContact O-N 2.81Å; T362-H366 PolarHBondContact O-ND1 3.33Å; T362-V408 HydrophobicContact CG2-CB 3.9Å; T362-V408 HydrophobicContact CG2-CG1 3.63Å
363	D	97.1	Very high	94.6	Very high	67 Å²	67	58.1 Å²	58.1	36%	0.358	31%	0.309	S	S	.	.	H	α-helix	trans	-65.6	-34.1	178.7	-71.1	-11.1	0	0	0	111	K359 E360 Q367	K359-D363 WeakPolarHBondContact CE-OD2 3.36Å; K359-D363 WeakPolarHBondContact CG-OD2 3.42Å; K359-D363 WeakPolarHBondContact O-CB 3.46Å; K359-D363 VanDerWaalsContact O-CG 3.22Å; K359-D363 PolarHBondContact O-N 3.46Å; E360-D363 PolarHBondContact O-N 2.82Å; D363-Q367 WeakPolarHBondContact O-CG 3.39Å; D363-Q367 PolarHBondContact O-N 2.95Å; D363-Q367 PolarHBondContact O-NE2 2.6Å
364	L	97.1	Very high	93.3	Very high	61 Å²	61	59.2 Å²	59.2	32%	0.319	31%	0.307	S	S	.	.	H	α-helix	trans	-64.5	-43.8	169.6	179.1	65.2	0	0	0	112.2	E360 F361 T362 Q367 L381 I385	E360-L364 PolarHBondContact O-N 2.94Å; E360-L364 VanDerWaalsContact O-N 3.07Å; F361-L364 PolarHBondContact O-N 3.17Å; T362-L364 VanDerWaalsContact C-N 3.29Å; T362-L364 PolarHBondContact O-N 2.59Å; L364-Q367 WeakPolarHBondContact O-CB 3.18Å; L364-Q367 PolarHBondContact O-N 3.48Å; L364-Q367 VanDerWaalsContact O-N 3.12Å; L364-L381 HydrophobicContact CD1-CD1 4Å; L364-L381 HydrophobicContact CD1-CD2 3.67Å; L364-I385 HydrophobicContact CD1-CG2 4.24Å
365	L	96.9	Very high	92.2	Very high	14 Å²	14	63 Å²	63	7%	0.073	32%	0.322	C	S	.	.	H	α-helix	trans	-67.5	-36	179.3	-66.4	176.9	0	0	0	112.4	F361 T362 Q367 D368 L389 I404	F361-L365 HydrophobicContact CD1-CD1 4.49Å; F361-L365 HydrophobicContact CE1-CD1 4.06Å; F361-L365 HydrophobicContact CE2-CD1 4.48Å; F361-L365 HydrophobicContact CZ-CD1 4.05Å; F361-L365 WeakPolarHBondContact O-CG 3.45Å; F361-L365 PolarHBondContact O-N 2.91Å; T362-L365 PolarHBondContact O-N 3.28Å; T362-L365 VanDerWaalsContact O-N 3.12Å; L365-Q367 PolarHBondContact O-N 2.92Å; L365-D368 VanDerWaalsContact O-CB 3.29Å; L365-D368 WeakPolarHBondContact O-CB 3.2Å; L365-D368 PolarHBondContact O-N 3.47Å; L365-D368 VanDerWaalsContact O-N 3.09Å; L365-L389 HydrophobicContact CD2-CD2 3.83Å; L365-I404 HydrophobicContact CD1-CB 4.12Å; L365-I404 HydrophobicContact CD1-CG2 3.58Å
366	H	94.7	Very high	91.1	Very high	114 Å²	114	66.1 Å²	66.1	53%	0.528	33%	0.331	S	S	.	.	H	α-helix	trans	-69.3	-15.5	172.5	-63	134.8	0	0	0	113.5	T362 R369	T362-H366 VanDerWaalsContact O-CG 3.31Å; T362-H366 PolarHBondContact O-N 2.81Å; T362-H366 PolarHBondContact O-ND1 3.33Å; H366-R369 PolarHBondContact O-NH1 3.35Å; H366-R369 PolarHBondContact O-NH2 3.2Å
367	Q	94.6	Very high	90.3	Very high	77 Å²	77	64.3 Å²	64.3	36%	0.36	33%	0.328	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86.7	-0	170.5	-73.5	170	81.7	0	0	113.5	D363 L364 L365 R369 V380 L381	D363-Q367 WeakPolarHBondContact O-CG 3.39Å; D363-Q367 PolarHBondContact O-N 2.95Å; D363-Q367 PolarHBondContact O-NE2 2.6Å; L364-Q367 WeakPolarHBondContact O-CB 3.18Å; L364-Q367 PolarHBondContact O-N 3.48Å; L364-Q367 VanDerWaalsContact O-N 3.12Å; L365-Q367 PolarHBondContact O-N 2.92Å; Q367-R369 WeakPolarHBondContact O-CG 3.28Å; Q367-R369 PolarHBondContact O-N 3.31Å; Q367-V380 HydrophobicContact CB-CG2 4.03Å; Q367-V380 HydrophobicContact CG-CG2 4.3Å; Q367-L381 HydrophobicContact CB-CD1 3.99Å; Q367-L381 HydrophobicContact CB-CD2 3.73Å; Q367-L381 HydrophobicContact CB-CG 3.9Å; Q367-L381 WeakPolarHBondContact O-CD1 3.01Å
368	D	94.8	Very high	89.7	Confident	26 Å²	26	63.9 Å²	63.9	14%	0.139	33%	0.333	C	S	.	.			trans	-60.4	128.4	170.7	-175.8	11.5	0	0	0	110.5	L365 T370 Q386 L389 S393	L365-D368 VanDerWaalsContact O-CB 3.29Å; L365-D368 WeakPolarHBondContact O-CB 3.2Å; L365-D368 PolarHBondContact O-N 3.47Å; L365-D368 VanDerWaalsContact O-N 3.09Å; D368-T370 VanDerWaalsContact CG-OG1 3.29Å; D368-T370 WeakPolarHBondContact OD1-CB 2.98Å; D368-T370 PolarHBondContact OD1-N 3.1Å; D368-T370 PolarHBondContact OD1-OG1 3.38Å; D368-T370 PolarHBondContact OD2-OG1 3.06Å; D368-Q386 PolarHBondContact OD1-NE2 3.32Å; D368-L389 HydrophobicContact CB-CD1 4.24Å; D368-S393 PolarHBondContact OD2-OG 3.17Å
369	R	93.4	Very high	89.2	Confident	67 Å²	67	68.3 Å²	68.3	25%	0.253	35%	0.352	S	S	.	.			trans	-113.1	20.2	179.5	-60.9	-69.4	169.1	-97.7	4.6	112.6	H366 Q367 P371 P377 A378 Q379 V380	H366-R369 PolarHBondContact O-NH1 3.35Å; H366-R369 PolarHBondContact O-NH2 3.2Å; Q367-R369 WeakPolarHBondContact O-CG 3.28Å; Q367-R369 PolarHBondContact O-N 3.31Å; R369-P371 WeakPolarHBondContact O-CD 3.41Å; R369-P377 HydrophobicContact CB-CG 3.99Å; R369-P377 HydrophobicContact CG-CG 4.41Å; R369-A378 WeakPolarHBondContact CD-O 3.45Å; R369-A378 WeakPolarHBondContact CG-O 3.33Å; R369-Q379 HydrophobicContact CB-CG 4.36Å; R369-V380 HydrophobicContact CG-CG2 4.03Å
370	T	92.3	Very high	89	Confident	12 Å²	12	67.4 Å²	67.4	7%	0.074	36%	0.355	C	S	.	.			trans	-56.3	127	177.5	-57.7	0	0	0	0	111.5	D368 N372 Q386 S390 L394	D368-T370 VanDerWaalsContact CG-OG1 3.29Å; D368-T370 WeakPolarHBondContact OD1-CB 2.98Å; D368-T370 PolarHBondContact OD1-N 3.1Å; D368-T370 PolarHBondContact OD1-OG1 3.38Å; D368-T370 PolarHBondContact OD2-OG1 3.06Å; T370-N372 PolarHBondContact O-N 2.98Å; T370-Q386 PolarHBondContact OG1-NE2 3.11Å; T370-S390 WeakPolarHBondContact OG1-CA 3.11Å; T370-S390 PolarHBondContact OG1-OG 3.44Å; T370-L394 HydrophobicContact CG2-CD2 4.37Å; T370-L394 HydrophobicContact CG2-CG 4.19Å
371	P	85.4	Confident	88.8	Confident	45 Å²	45	63.4 Å²	63.4	29%	0.292	34%	0.337	S	S	.	.			trans	-61	81.2	174.2	-32.5	41.6	0	0	0	115.4	R248 R369	R248-P371 WeakPolarHBondContact CD-O 3.34Å; R248-P371 VanDerWaalsContact CZ-O 3.26Å; R248-P371 PolarHBondContact NE-O 3.07Å; R248-P371 PolarHBondContact NH1-O 2.99Å; R369-P371 WeakPolarHBondContact O-CD 3.41Å
372	N	81	Confident	88.7	Confident	33 Å²	33	65.7 Å²	65.7	18%	0.176	35%	0.349	C	S	.	.			trans	-101.1	144.1	171.2	-67.4	-12	0	0	0	111.1	T370 N374 N375 S393 G398	T370-N372 PolarHBondContact O-N 2.98Å; N372-N374 PolarHBondContact O-N 3Å; N372-N375 PolarHBondContact O-N 3.18Å; N372-S393 PolarHBondContact ND2-OG 3.44Å; N372-G398 WeakPolarHBondContact ND2-CA 3.4Å
373	G	79.5	Confident	88.5	Confident	26 Å²	26	68.7 Å²	68.7	27%	0.268	37%	0.369	S	S	.	.	T	Hydrogen-bonded Turn	trans	54.2	-133.7	-170.1	0	0	0	0	0	111.8	R248 E306 R376	R248-G373 PolarHBondContact NH1-O 2.95Å; R248-G373 PolarHBondContact NH2-O 2.66Å; E306-G373 WeakPolarHBondContact OE2-CA 3.33Å; E306-G373 PolarHBondContact OE2-N 2.89Å; G373-R376 PolarHBondContact O-NH1 3.06Å
374	N	71.2	Confident	88.5	Confident	81 Å²	81	71.4 Å²	71.4	43%	0.433	38%	0.383	S	S	.	.	T	Hydrogen-bonded Turn	trans	-91.1	-5.7	179.3	-66.4	-1.4	0	0	0	113.3	N372	N372-N374 PolarHBondContact O-N 3Å
375	N	73.7	Confident	88.5	Confident	121 Å²	121	72.3 Å²	72.3	65%	0.647	39%	0.387	S	S	*	.			trans	-73.7	140.4	-178.4	-67.4	-8.2	0	0	0	110.7	N372	N372-N375 PolarHBondContact O-N 3.18Å
376	R	74.7	Confident	88.4	Confident	120 Å²	120	71.6 Å²	71.6	45%	0.453	38%	0.384	S	S	.	.			trans	-139	60.8	177.6	-68.7	-64.5	-175.7	-73.4	-3.5	110.6	G373	G373-R376 PolarHBondContact O-NH1 3.06Å
377	P	81.8	Confident	88.5	Confident	58 Å²	58	70.7 Å²	70.7	38%	0.377	38%	0.383	S	S	.	.	P	Polyproline II helix	trans	-75.9	151.2	-175.3	36.1	-36.8	0	0	0	110.7	R369	R369-P377 HydrophobicContact CB-CG 3.99Å; R369-P377 HydrophobicContact CG-CG 4.41Å
378	A	85.9	Confident	88.6	Confident	82 Å²	82	71.3 Å²	71.3	68%	0.678	40%	0.395	S	S	*	.	P	Polyproline II helix	trans	-63.7	139.5	175.5	0	0	0	0	0	110.7	R369	R369-A378 WeakPolarHBondContact CD-O 3.45Å; R369-A378 WeakPolarHBondContact CG-O 3.33Å
379	Q	88.2	Confident	88.7	Confident	116 Å²	116	71 Å²	71	54%	0.542	39%	0.393	S	S	.	.	P	Polyproline II helix	trans	-68.7	132.3	178.6	-65.6	-178.6	-21.2	0	0	110.5	R369 Q386	R369-Q379 HydrophobicContact CB-CG 4.36Å; Q379-Q386 HydrophobicContact CB-CG 4.46Å; Q379-Q386 HydrophobicContact CG-CG 3.97Å
380	V	92.8	Very high	88.8	Confident	85 Å²	85	68.6 Å²	68.6	52%	0.515	39%	0.387	S	S	.	.			trans	-116.2	-14.7	-179.9	-58.5	0	0	0	0	113.2	Q367 R369	Q367-V380 HydrophobicContact CB-CG2 4.03Å; Q367-V380 HydrophobicContact CG-CG2 4.3Å; R369-V380 HydrophobicContact CG-CG2 4.03Å
381	L	94.3	Very high	89	Confident	24 Å²	24	73.2 Å²	73.2	13%	0.126	41%	0.407	C	S	.	.	S	Bend	trans	-95.9	153.6	180	-65.1	177.2	0	0	0	111	L364 Q367 I385 Q386 L389	L364-L381 HydrophobicContact CD1-CD1 4Å; L364-L381 HydrophobicContact CD1-CD2 3.67Å; Q367-L381 HydrophobicContact CB-CD1 3.99Å; Q367-L381 HydrophobicContact CB-CD2 3.73Å; Q367-L381 HydrophobicContact CB-CG 3.9Å; Q367-L381 WeakPolarHBondContact O-CD1 3.01Å; L381-I385 HydrophobicContact CD1-CG2 4.33Å; L381-Q386 HydrophobicContact CB-CB 4.24Å; L381-L389 HydrophobicContact CD1-CD1 3.51Å
382	E	95.2	Very high	89.5	Confident	140 Å²	140	74.4 Å²	74.4	65%	0.654	41%	0.408	S	S	*	.			trans	-49.2	134.8	170.9	-76.7	-63.3	157.7	0	0	111.5	N384 I385 Q386	E382-N384 PolarHBondContact O-N 3.39Å; E382-I385 HydrophobicContact CB-CG1 4.4Å; E382-I385 PolarHBondContact O-N 3.21Å; E382-Q386 PolarHBondContact O-N 3.44Å
383	P	94.8	Very high	90.3	Very high	73 Å²	73	73 Å²	73	47%	0.474	40%	0.4	S	S	.	.	H	α-helix	trans	-53.5	-37.1	-171.6	-29.9	35.6	0	0	0	114.2	I385 Q386 N387	P383-I385 PolarHBondContact O-N 3.41Å; P383-Q386 PolarHBondContact O-N 2.74Å; P383-N387 WeakPolarHBondContact O-CB 3.44Å; P383-N387 PolarHBondContact O-N 3.41Å; P383-N387 PolarHBondContact O-ND2 3.3Å
384	N	96.6	Very high	91.1	Very high	125 Å²	125	73.4 Å²	73.4	67%	0.668	40%	0.396	S	S	*	.	H	α-helix	trans	-63.5	-40.8	178.3	-67.5	-23.4	0	0	0	112.3	E382 C388	E382-N384 PolarHBondContact O-N 3.39Å; N384-C388 PolarHBondContact O-N 3.07Å; N384-C388 PolarHBondContact O-SG 3.48Å; N384-C388 VanDerWaalsContact O-SG 3.33Å
385	I	96.9	Very high	92.2	Very high	79 Å²	79	71.2 Å²	71.2	41%	0.405	38%	0.384	S	S	.	.	H	α-helix	trans	-74.1	-45.9	177.8	-57.2	-58.9	0	0	0	110.1	L364 L381 E382 P383 N387 C388 L389	L364-I385 HydrophobicContact CD1-CG2 4.24Å; L381-I385 HydrophobicContact CD1-CG2 4.33Å; E382-I385 HydrophobicContact CB-CG1 4.4Å; E382-I385 PolarHBondContact O-N 3.21Å; P383-I385 PolarHBondContact O-N 3.41Å; I385-N387 VanDerWaalsContact C-N 3.28Å; I385-N387 PolarHBondContact O-N 2.71Å; I385-C388 PolarHBondContact O-N 2.73Å; I385-L389 HydrophobicContact CG2-CD1 3.99Å; I385-L389 HydrophobicContact CG2-CG 4.38Å; I385-L389 WeakPolarHBondContact O-CG 3.47Å; I385-L389 PolarHBondContact O-N 3.2Å
386	Q	95.9	Very high	93.3	Very high	0 Å²	0	65.9 Å²	65.9	0%	0	36%	0.356	C	S	.	.	H	α-helix	trans	-60.4	-37.3	177.4	-174.7	56.1	66.8	0	0	111.7	D368 T370 Q379 L381 E382 P383 S390	D368-Q386 PolarHBondContact OD1-NE2 3.32Å; T370-Q386 PolarHBondContact OG1-NE2 3.11Å; Q379-Q386 HydrophobicContact CB-CG 4.46Å; Q379-Q386 HydrophobicContact CG-CG 3.97Å; L381-Q386 HydrophobicContact CB-CB 4.24Å; E382-Q386 PolarHBondContact O-N 3.44Å; P383-Q386 PolarHBondContact O-N 2.74Å; Q386-S390 PolarHBondContact NE2-OG 3.31Å; Q386-S390 VanDerWaalsContact NE2-OG 3.1Å; Q386-S390 VanDerWaalsContact O-CB 3.25Å; Q386-S390 WeakPolarHBondContact O-CB 3.42Å; Q386-S390 PolarHBondContact O-N 3.08Å; Q386-S390 PolarHBondContact O-OG 3.08Å
387	N	95.5	Very high	94.3	Very high	94 Å²	94	60.3 Å²	60.3	50%	0.503	34%	0.335	S	S	.	.	H	α-helix	trans	-65.5	-42.7	176.3	-74.3	-25.4	0	0	0	112.3	P383 I385 S390 H391	P383-N387 WeakPolarHBondContact O-CB 3.44Å; P383-N387 PolarHBondContact O-N 3.41Å; P383-N387 PolarHBondContact O-ND2 3.3Å; I385-N387 VanDerWaalsContact C-N 3.28Å; I385-N387 PolarHBondContact O-N 2.71Å; N387-S390 PolarHBondContact O-N 3.3Å; N387-H391 PolarHBondContact O-N 3.09Å
388	C	97	Very high	95	Very high	90 Å²	90	57.8 Å²	57.8	61%	0.608	32%	0.319	S	S	*	.	H	α-helix	trans	-63.7	-45.9	175.3	-71.5	0	0	0	0	112.1	N384 I385 S390 H391 F392	N384-C388 PolarHBondContact O-N 3.07Å; N384-C388 PolarHBondContact O-SG 3.48Å; N384-C388 VanDerWaalsContact O-SG 3.33Å; I385-C388 PolarHBondContact O-N 2.73Å; C388-S390 VanDerWaalsContact C-N 3.35Å; C388-H391 PolarHBondContact O-N 3.35Å; C388-F392 PolarHBondContact O-N 2.92Å; C388-F392 VanDerWaalsContact O-N 3.12Å
389	L	97	Very high	95.5	Very high	20 Å²	20	56 Å²	56	11%	0.105	30%	0.296	C	S	.	.	H	α-helix	trans	-62.9	-41.4	174.9	-67.6	174.5	0	0	0	111.2	L365 D368 L381 I385 H391 F392 S393	L365-L389 HydrophobicContact CD2-CD2 3.83Å; D368-L389 HydrophobicContact CB-CD1 4.24Å; L381-L389 HydrophobicContact CD1-CD1 3.51Å; I385-L389 HydrophobicContact CG2-CD1 3.99Å; I385-L389 HydrophobicContact CG2-CG 4.38Å; I385-L389 WeakPolarHBondContact O-CG 3.47Å; I385-L389 PolarHBondContact O-N 3.2Å; L389-H391 PolarHBondContact O-N 3.47Å; L389-F392 PolarHBondContact O-N 3.45Å; L389-S393 WeakPolarHBondContact O-CB 3.22Å; L389-S393 PolarHBondContact O-N 3.13Å
390	S	95.7	Very high	96	Very high	17 Å²	17	50.7 Å²	50.7	12%	0.119	27%	0.273	C	S	.	.	H	α-helix	trans	-61.4	-43.7	175.7	-53.3	0	0	0	0	112.3	T370 Q386 N387 C388 F392 S393 L394	T370-S390 WeakPolarHBondContact OG1-CA 3.11Å; T370-S390 PolarHBondContact OG1-OG 3.44Å; Q386-S390 PolarHBondContact NE2-OG 3.31Å; Q386-S390 VanDerWaalsContact NE2-OG 3.1Å; Q386-S390 VanDerWaalsContact O-CB 3.25Å; Q386-S390 WeakPolarHBondContact O-CB 3.42Å; Q386-S390 PolarHBondContact O-N 3.08Å; Q386-S390 PolarHBondContact O-OG 3.08Å; N387-S390 PolarHBondContact O-N 3.3Å; C388-S390 VanDerWaalsContact C-N 3.35Å; S390-F392 VanDerWaalsContact C-N 3.35Å; S390-F392 PolarHBondContact O-N 3.32Å; S390-S393 PolarHBondContact O-N 2Å; S390-L394 WeakPolarHBondContact O-CB 3.3Å; S390-L394 WeakPolarHBondContact O-CD1 3.28Å; S390-L394 WeakPolarHBondContact O-CG 3.21Å; S390-L394 PolarHBondContact O-N 3.11Å
391	H	96.2	Very high	96.2	Very high	108 Å²	108	47.2 Å²	47.2	50%	0.5	25%	0.252	S	S	.	.	H	α-helix	trans	-59.2	-46.3	175.1	-179.1	-78.7	0	0	0	111.7	N387 C388 L389 I395	N387-H391 PolarHBondContact O-N 3.09Å; C388-H391 PolarHBondContact O-N 3.35Å; L389-H391 PolarHBondContact O-N 3.47Å; H391-I395 WeakPolarHBondContact O-CB 3.48Å; H391-I395 PolarHBondContact O-N 3.02Å
392	F	96.8	Very high	96.3	Very high	70 Å²	70	50 Å²	50	31%	0.307	27%	0.265	S	S	.	.	H	α-helix	trans	-66.9	-43.4	179	178.4	-115.5	0	0	0	113	C388 L389 S390 I395 T396 G400 I404	C388-F392 PolarHBondContact O-N 2.92Å; C388-F392 VanDerWaalsContact O-N 3.12Å; L389-F392 PolarHBondContact O-N 3.45Å; S390-F392 VanDerWaalsContact C-N 3.35Å; S390-F392 PolarHBondContact O-N 3.32Å; F392-I395 PolarHBondContact O-N 3.08Å; F392-T396 HydrophobicContact CD2-CG2 4.05Å; F392-T396 HydrophobicContact CE2-CG2 3.77Å; F392-T396 HydrophobicContact CZ-CG2 4.22Å; F392-T396 WeakPolarHBondContact O-CB 3.47Å; F392-T396 WeakPolarHBondContact O-CG2 3.49Å; F392-T396 PolarHBondContact O-N 3.28Å; F392-T396 PolarHBondContact O-OG1 2.87Å; F392-G400 VanDerWaalsContact CE1-C 3.45Å; F392-I404 HydrophobicContact CE1-CD1 3.78Å; F392-I404 HydrophobicContact CZ-CD1 3.7Å
393	S	96.4	Very high	96.4	Very high	4 Å²	4	43.9 Å²	43.9	3%	0.028	24%	0.238	C	C	.	.	H	α-helix	trans	-67.5	-39.2	-179.5	-169.7	0	0	0	0	111.3	D368 N372 L389 S390 H397 G398	D368-S393 PolarHBondContact OD2-OG 3.17Å; N372-S393 PolarHBondContact ND2-OG 3.44Å; L389-S393 WeakPolarHBondContact O-CB 3.22Å; L389-S393 PolarHBondContact O-N 3.13Å; S390-S393 PolarHBondContact O-N 2Å; S393-H397 WeakPolarHBondContact O-CA 3.48Å; S393-H397 PolarHBondContact O-N 2.99Å; S393-G398 PolarHBondContact O-N 3.33Å
394	L	95.7	Very high	96.6	Very high	35 Å²	35	43.1 Å²	43.1	18%	0.183	23%	0.23	C	C	.	.	H	α-helix	trans	-68.7	-42.8	173.1	-69.3	171.3	0	0	0	112.9	R248 P253 T370 S390 T396 H397	R248-L394 HydrophobicContact CB-CD2 4.24Å; R248-L394 HydrophobicContact CG-CD2 4.07Å; P253-L394 HydrophobicContact CG-CB 3.95Å; T370-L394 HydrophobicContact CG2-CD2 4.37Å; T370-L394 HydrophobicContact CG2-CG 4.19Å; S390-L394 WeakPolarHBondContact O-CB 3.3Å; S390-L394 WeakPolarHBondContact O-CD1 3.28Å; S390-L394 WeakPolarHBondContact O-CG 3.21Å; S390-L394 PolarHBondContact O-N 3.11Å; L394-T396 VanDerWaalsContact C-N 3.28Å; L394-T396 PolarHBondContact O-N 3.42Å; L394-H397 PolarHBondContact O-CD2 2.92Å; L394-H397 PolarHBondContact O-N 3.36Å; L394-H397 PolarHBondContact O-NE2 2.84Å; L394-H397 VanDerWaalsContact O-NE2 3.13Å
395	I	96	Very high	96.7	Very high	34 Å²	34	38 Å²	38	17%	0.174	20%	0.203	C	C	.	.	H	α-helix	trans	-74.6	-18.7	-178.4	-148.2	75.2	0	0	0	113.4	P253 E254 A296 H391 F392 H397	P253-I395 HydrophobicContact CB-CD1 4.13Å; P253-I395 HydrophobicContact CG-CB 4.46Å; P253-I395 HydrophobicContact CG-CD1 3.84Å; E254-I395 HydrophobicContact CG-CD1 3.7Å; A296-I395 HydrophobicContact CB-CD1 3.58Å; H391-I395 WeakPolarHBondContact O-CB 3.48Å; H391-I395 PolarHBondContact O-N 3.02Å; F392-I395 PolarHBondContact O-N 3.08Å; I395-H397 PolarHBondContact O-CE1 2.86Å
396	T	96.6	Very high	96.8	Very high	9 Å²	9	34.7 Å²	34.7	6%	0.055	19%	0.188	C	C	.	.	T	Hydrogen-bonded Turn	trans	-105.2	1.6	175	63.3	0	0	0	0	113.4	L301 F392 L394 G398 F399 G400	L301-T396 HydrophobicContact CD1-CG2 3.86Å; F392-T396 HydrophobicContact CD2-CG2 4.05Å; F392-T396 HydrophobicContact CE2-CG2 3.77Å; F392-T396 HydrophobicContact CZ-CG2 4.22Å; F392-T396 WeakPolarHBondContact O-CB 3.47Å; F392-T396 WeakPolarHBondContact O-CG2 3.49Å; F392-T396 PolarHBondContact O-N 3.28Å; F392-T396 PolarHBondContact O-OG1 2.87Å; L394-T396 VanDerWaalsContact C-N 3.28Å; L394-T396 PolarHBondContact O-N 3.42Å; T396-G398 PolarHBondContact O-N 3.07Å; T396-F399 VanDerWaalsContact O-CB 3.28Å; T396-F399 WeakPolarHBondContact O-CB 3.3Å; T396-F399 PolarHBondContact O-N 2.7Å; T396-G400 WeakPolarHBondContact OG1-CA 3.42Å; T396-G400 PolarHBondContact OG1-N 3.21Å
397	H	96	Very high	96.9	Very high	4 Å²	4	36.8 Å²	36.8	2%	0.019	21%	0.205	C	C	.	.	T	Hydrogen-bonded Turn	trans	55.6	35.3	178.8	-44.6	101.9	0	0	0	113.2	R249 E254 L301 T302 E306 A309 S393 L394 I395 F399	R249-H397 PolarHBondContact NH1-CD2 3.06Å; R249-H397 VanDerWaalsContact NH1-CD2 3.3Å; R249-H397 PolarHBondContact NH1-NE2 2.97Å; R249-H397 PolarHBondContact NH2-CD2 3Å; R249-H397 VanDerWaalsContact NH2-CD2 3.32Å; E254-H397 IonicContact OE1-CE1 3.66Å; E254-H397 PolarHBondContact OE1-CE1 3.45Å; E254-H397 VanDerWaalsContact OE1-CE1 3.3Å; E254-H397 IonicContact OE1-NE2 2.83Å; E254-H397 PolarHBondContact OE1-NE2 2.9Å; E254-H397 IonicContact OE2-CD2 2.72Å; E254-H397 IonicContact OE2-NE2 3.76Å; E254-H397 PolarHBondContact OE2-NE2 3.3Å; L301-H397 PolarHBondContact O-CE1 3.12Å; L301-H397 PolarHBondContact O-ND1 3.36Å; T302-H397 WeakPolarHBondContact CA-CE1 3.34Å; T302-H397 PolarHBondContact N-CE1 3.21Å; E306-H397 HydrophobicContact CG-CB 3.98Å; A309-H397 HydrophobicContact CB-CB 3.75Å; A309-H397 VanDerWaalsContact CB-O 3.3Å; A309-H397 WeakPolarHBondContact CB-O 3.34Å; S393-H397 WeakPolarHBondContact O-CA 3.48Å; S393-H397 PolarHBondContact O-N 2.99Å; L394-H397 PolarHBondContact O-CD2 2.92Å; L394-H397 PolarHBondContact O-N 3.36Å; L394-H397 PolarHBondContact O-NE2 2.84Å; L394-H397 VanDerWaalsContact O-NE2 3.13Å; I395-H397 PolarHBondContact O-CE1 2.86Å; H397-F399 VanDerWaalsContact C-N 3.34Å
398	G	95.2	Very high	97	Very high	4 Å²	4	33.3 Å²	33.3	4%	0.041	19%	0.187	C	C	.	.	T	Hydrogen-bonded Turn	trans	83.4	-6.6	-177.2	0	0	0	0	0	115.7	N372 S393 T396 Q402	N372-G398 WeakPolarHBondContact ND2-CA 3.4Å; S393-G398 PolarHBondContact O-N 3.33Å; T396-G398 PolarHBondContact O-N 3.07Å; G398-Q402 PolarHBondContact O-NE2 2.94Å
399	F	97.5	Very high	97.1	Very high	44 Å²	44	31.3 Å²	31.3	19%	0.193	17%	0.174	C	C	.	.	H	α-helix	trans	-65.8	-43.9	177	170.6	-98.6	0	0	0	112.4	L301 A309 L312 A313 T396 H397 S401 Q402 A403	L301-F399 HydrophobicContact CD1-CD1 4.36Å; L301-F399 HydrophobicContact CD2-CD1 4.03Å; L301-F399 HydrophobicContact CD2-CG 4.4Å; A309-F399 HydrophobicContact CB-CB 4.06Å; L312-F399 HydrophobicContact CB-CD2 4.32Å; L312-F399 HydrophobicContact CD2-CD2 4.11Å; L312-F399 HydrophobicContact CD2-CE2 3.99Å; L312-F399 HydrophobicContact CG-CD2 4.06Å; L312-F399 HydrophobicContact CG-CE2 3.82Å; A313-F399 HydrophobicContact CB-CD2 3.75Å; A313-F399 HydrophobicContact CB-CE2 4.33Å; T396-F399 VanDerWaalsContact O-CB 3.28Å; T396-F399 WeakPolarHBondContact O-CB 3.3Å; T396-F399 PolarHBondContact O-N 2.7Å; H397-F399 VanDerWaalsContact C-N 3.34Å; F399-S401 PolarHBondContact O-N 3Å; F399-Q402 PolarHBondContact O-N 2.99Å; F399-A403 HydrophobicContact CD1-CB 4.22Å; F399-A403 HydrophobicContact CD2-CB 4.38Å; F399-A403 HydrophobicContact CE1-CB 3.74Å; F399-A403 HydrophobicContact CE2-CB 3.89Å; F399-A403 HydrophobicContact CZ-CB 3.55Å; F399-A403 WeakPolarHBondContact O-CB 3.06Å; F399-A403 PolarHBondContact O-N 3.44Å
400	G	97.4	Very high	97.1	Very high	5 Å²	5	30.7 Å²	30.7	5%	0.052	17%	0.172	C	C	.	.	H	α-helix	trans	-59.1	-55.9	-163.3	0	0	0	0	0	114.3	F392 T396 Q402 A403 I404	F392-G400 VanDerWaalsContact CE1-C 3.45Å; T396-G400 WeakPolarHBondContact OG1-CA 3.42Å; T396-G400 PolarHBondContact OG1-N 3.21Å; G400-Q402 VanDerWaalsContact C-N 3.33Å; G400-Q402 PolarHBondContact O-N 3.21Å; G400-A403 PolarHBondContact O-N 2.83Å; G400-I404 WeakPolarHBondContact O-CG1 3.21Å; G400-I404 PolarHBondContact O-N 3.14Å
401	S	97.1	Very high	97.3	Very high	12 Å²	12	32.9 Å²	32.9	8%	0.084	18%	0.184	C	C	.	.	H	α-helix	trans	-63.7	-39.3	-177.2	-50.5	0	0	0	0	111.8	F399 I404 C405	F399-S401 PolarHBondContact O-N 3Å; S401-I404 PolarHBondContact O-N 3.09Å; S401-C405 PolarHBondContact O-N 2.83Å; S401-C405 PolarHBondContact O-SG 2.97Å
402	Q	96.9	Very high	97.3	Very high	83 Å²	83	29.2 Å²	29.2	39%	0.388	17%	0.168	S	C	.	.	H	α-helix	trans	-66.2	-43.3	177.5	-70.3	179.8	92.9	0	0	111.9	A313 G398 F399 G400 I404 C405 A406	A313-Q402 HydrophobicContact CB-CB 3.64Å; G398-Q402 PolarHBondContact O-NE2 2.94Å; F399-Q402 PolarHBondContact O-N 2.99Å; G400-Q402 VanDerWaalsContact C-N 3.33Å; G400-Q402 PolarHBondContact O-N 3.21Å; Q402-I404 VanDerWaalsContact C-N 3.33Å; Q402-I404 PolarHBondContact O-N 3.23Å; Q402-C405 PolarHBondContact O-N 3.36Å; Q402-A406 WeakPolarHBondContact O-CB 3.32Å; Q402-A406 PolarHBondContact O-N 3.11Å
403	A	98.3	Very high	97.4	Very high	12 Å²	12	27.6 Å²	27.6	10%	0.099	16%	0.162	C	C	.	.	H	α-helix	trans	-64.8	-35.9	176.4	0	0	0	0	0	112.5	F316 F399 G400 A407	F316-A403 HydrophobicContact CD1-CB 4.06Å; F316-A403 HydrophobicContact CE1-CB 4.27Å; F399-A403 HydrophobicContact CD1-CB 4.22Å; F399-A403 HydrophobicContact CD2-CB 4.38Å; F399-A403 HydrophobicContact CE1-CB 3.74Å; F399-A403 HydrophobicContact CE2-CB 3.89Å; F399-A403 HydrophobicContact CZ-CB 3.55Å; F399-A403 WeakPolarHBondContact O-CB 3.06Å; F399-A403 PolarHBondContact O-N 3.44Å; G400-A403 PolarHBondContact O-N 2.83Å; A403-A407 PolarHBondContact O-N 3.01Å
404	I	98.5	Very high	97.5	Very high	57 Å²	57	29.1 Å²	29.1	29%	0.292	17%	0.168	S	C	.	.	H	α-helix	trans	-65.4	-47.8	172.5	-67.5	169.9	0	0	0	110.5	F361 L365 F392 G400 S401 Q402 A406 A407 V408	F361-I404 HydrophobicContact CE1-CG2 3.55Å; F361-I404 HydrophobicContact CZ-CG2 4.05Å; L365-I404 HydrophobicContact CD1-CB 4.12Å; L365-I404 HydrophobicContact CD1-CG2 3.58Å; F392-I404 HydrophobicContact CE1-CD1 3.78Å; F392-I404 HydrophobicContact CZ-CD1 3.7Å; G400-I404 WeakPolarHBondContact O-CG1 3.21Å; G400-I404 PolarHBondContact O-N 3.14Å; S401-I404 PolarHBondContact O-N 3.09Å; Q402-I404 VanDerWaalsContact C-N 3.33Å; Q402-I404 PolarHBondContact O-N 3.23Å; I404-A406 VanDerWaalsContact C-N 3.31Å; I404-A406 PolarHBondContact O-N 3.48Å; I404-A407 PolarHBondContact O-N 3.06Å; I404-V408 HydrophobicContact CG2-CG2 4.29Å; I404-V408 WeakPolarHBondContact O-CG2 3.49Å; I404-V408 PolarHBondContact O-N 3.39Å
405	C	98.3	Very high	97.6	Very high	17 Å²	17	27.6 Å²	27.6	12%	0.115	16%	0.16	C	C	.	.	H	α-helix	trans	-58.3	-41.3	176.2	-72.4	0	0	0	0	112.3	S401 Q402 V408 S409	S401-C405 PolarHBondContact O-N 2.83Å; S401-C405 PolarHBondContact O-SG 2.97Å; Q402-C405 PolarHBondContact O-N 3.36Å; C405-V408 PolarHBondContact O-N 3.32Å; C405-S409 WeakPolarHBondContact O-CB 3.49Å; C405-S409 PolarHBondContact O-N 3.43Å
406	A	98.4	Very high	97.7	Very high	9 Å²	9	30.4 Å²	30.4	7%	0.074	17%	0.171	C	C	.	.	H	α-helix	trans	-60.1	-48.6	174.8	0	0	0	0	0	112.7	F316 A317 Q402 I404 V408 S409 A410	F316-A406 HydrophobicContact CD1-CB 3.88Å; F316-A406 HydrophobicContact CE1-CB 4.05Å; A317-A406 HydrophobicContact CB-CB 3.82Å; Q402-A406 WeakPolarHBondContact O-CB 3.32Å; Q402-A406 PolarHBondContact O-N 3.11Å; I404-A406 VanDerWaalsContact C-N 3.31Å; I404-A406 PolarHBondContact O-N 3.48Å; A406-V408 PolarHBondContact O-N 3.19Å; A406-S409 WeakPolarHBondContact O-CB 3.48Å; A406-S409 PolarHBondContact O-N 3.05Å; A406-A410 PolarHBondContact O-N 3.29Å
407	A	98.3	Very high	97.7	Very high	45 Å²	45	32.9 Å²	32.9	37%	0.372	18%	0.182	S	C	.	.	H	α-helix	trans	-63.8	-39.5	178.1	0	0	0	0	0	112.3	A403 I404 A410 V411	A403-A407 PolarHBondContact O-N 3.01Å; I404-A407 PolarHBondContact O-N 3.06Å; A407-A410 PolarHBondContact O-N 3.03Å; A407-V411 PolarHBondContact O-N 3.35Å; A407-V411 VanDerWaalsContact O-N 3.17Å
408	V	98.5	Very high	97.8	Very high	20 Å²	20	32.7 Å²	32.7	12%	0.121	18%	0.181	C	C	.	.	H	α-helix	trans	-68.9	-34.8	175.6	177.2	0	0	0	0	111.5	C358 F361 T362 I404 C405 A406 V411 Q412	C358-V408 HydrophobicContact CB-CG1 3.62Å; F361-V408 HydrophobicContact CD1-CG2 4.21Å; F361-V408 HydrophobicContact CE1-CG2 4.37Å; T362-V408 HydrophobicContact CG2-CB 3.9Å; T362-V408 HydrophobicContact CG2-CG1 3.63Å; I404-V408 HydrophobicContact CG2-CG2 4.29Å; I404-V408 WeakPolarHBondContact O-CG2 3.49Å; I404-V408 PolarHBondContact O-N 3.39Å; C405-V408 PolarHBondContact O-N 3.32Å; A406-V408 PolarHBondContact O-N 3.19Å; V408-V411 WeakPolarHBondContact O-CB 3.37Å; V408-V411 PolarHBondContact O-N 3.44Å; V408-Q412 HydrophobicContact CG1-CG 4.49Å; V408-Q412 WeakPolarHBondContact O-CG 3.27Å; V408-Q412 PolarHBondContact O-N 3.1Å
409	S	98	Very high	97.8	Very high	49 Å²	49	33.4 Å²	33.4	34%	0.343	18%	0.183	S	C	.	.	H	α-helix	trans	-61.3	-43.3	172.8	-173.1	0	0	0	0	111.9	C405 A406 V411 Q412 N413	C405-S409 WeakPolarHBondContact O-CB 3.49Å; C405-S409 PolarHBondContact O-N 3.43Å; A406-S409 WeakPolarHBondContact O-CB 3.48Å; A406-S409 PolarHBondContact O-N 3.05Å; S409-V411 VanDerWaalsContact C-N 3.33Å; S409-V411 PolarHBondContact O-N 3.35Å; S409-Q412 WeakPolarHBondContact O-CB 3.34Å; S409-Q412 PolarHBondContact O-N 3.3Å; S409-Q412 VanDerWaalsContact O-N 3.15Å; S409-N413 PolarHBondContact O-N 2.98Å
410	A	98.3	Very high	97.7	Very high	6 Å²	6	34.8 Å²	34.8	5%	0.05	19%	0.192	C	C	.	.	H	α-helix	trans	-60.4	-39.9	173.5	0	0	0	0	0	112.4	C320 F324 A406 A407 N413 Y414	C320-A410 HydrophobicContact CB-CB 4.35Å; F324-A410 HydrophobicContact CB-CB 4.44Å; F324-A410 HydrophobicContact CD1-CB 3.82Å; F324-A410 HydrophobicContact CE1-CB 4.24Å; F324-A410 HydrophobicContact CG-CB 4.05Å; A406-A410 PolarHBondContact O-N 3.29Å; A407-A410 PolarHBondContact O-N 3.03Å; A410-N413 PolarHBondContact O-N 2.96Å; A410-Y414 PolarHBondContact O-N 2.97Å
411	V	98.1	Very high	97.5	Very high	63 Å²	63	35.5 Å²	35.5	38%	0.382	20%	0.197	S	C	.	.	H	α-helix	trans	-64.3	-43.8	172.3	173.7	0	0	0	0	111.5	A407 V408 S409 N413 Y414 I415	A407-V411 PolarHBondContact O-N 3.35Å; A407-V411 VanDerWaalsContact O-N 3.17Å; V408-V411 WeakPolarHBondContact O-CB 3.37Å; V408-V411 PolarHBondContact O-N 3.44Å; S409-V411 VanDerWaalsContact C-N 3.33Å; S409-V411 PolarHBondContact O-N 3.35Å; V411-N413 VanDerWaalsContact C-N 3.31Å; V411-N413 PolarHBondContact O-N 3.13Å; V411-Y414 HydrophobicContact CG1-CD1 4.48Å; V411-Y414 WeakPolarHBondContact O-CD1 3.34Å; V411-Y414 PolarHBondContact O-N 3.05Å; V411-I415 HydrophobicContact CG1-CD1 3.97Å; V411-I415 WeakPolarHBondContact O-CG1 3.44Å; V411-I415 PolarHBondContact O-N 3.48Å
412	Q	98	Very high	97.3	Very high	32 Å²	32	35 Å²	35	15%	0.15	19%	0.193	C	C	.	.	H	α-helix	trans	-62	-37.1	176	-75.1	177.5	-21.7	0	0	112.1	C358 V408 S409 I415 K416	C358-Q412 HydrophobicContact CB-CG 3.7Å; V408-Q412 HydrophobicContact CG1-CG 4.49Å; V408-Q412 WeakPolarHBondContact O-CG 3.27Å; V408-Q412 PolarHBondContact O-N 3.1Å; S409-Q412 WeakPolarHBondContact O-CB 3.34Å; S409-Q412 PolarHBondContact O-N 3.3Å; S409-Q412 VanDerWaalsContact O-N 3.15Å; Q412-I415 PolarHBondContact O-N 3.12Å; Q412-K416 VanDerWaalsContact O-CG 3.3Å; Q412-K416 WeakPolarHBondContact O-CG 3.42Å; Q412-K416 PolarHBondContact O-N 3.06Å
413	N	97.9	Very high	97	Very high	36 Å²	36	34.2 Å²	34.2	19%	0.193	19%	0.192	C	C	.	.	H	α-helix	trans	-67.9	-41.3	176	-72.4	-14.8	0	0	0	112.1	S326 S409 A410 V411 I415 K416 E417	S326-N413 WeakPolarHBondContact OG-CB 3.23Å; S409-N413 PolarHBondContact O-N 2.98Å; A410-N413 PolarHBondContact O-N 2.96Å; V411-N413 VanDerWaalsContact C-N 3.31Å; V411-N413 PolarHBondContact O-N 3.13Å; N413-I415 VanDerWaalsContact C-N 3.33Å; N413-I415 PolarHBondContact O-N 3.29Å; N413-K416 PolarHBondContact O-N 3.16Å; N413-K416 PolarHBondContact OD1-NZ 3.43Å; N413-E417 PolarHBondContact O-N 3.13Å
414	Y	97.9	Very high	96.6	Very high	36 Å²	36	39.7 Å²	39.7	14%	0.141	21%	0.214	C	C	.	.	H	α-helix	trans	-57.6	-43.4	167.9	144	-105.3	0	0	0	112.1	V329 A330 L333 R347 A410 V411 E417 A418	V329-Y414 HydrophobicContact CB-CD2 4.32Å; V329-Y414 HydrophobicContact CG1-CD2 3.73Å; V329-Y414 HydrophobicContact CG1-CE2 4.12Å; V329-Y414 HydrophobicContact CG1-CG 4.25Å; A330-Y414 HydrophobicContact CB-CD2 3.98Å; A330-Y414 HydrophobicContact CB-CE2 4.41Å; L333-Y414 HydrophobicContact CB-CE2 4.28Å; L333-Y414 HydrophobicContact CD1-CE2 3.74Å; R347-Y414 PolarHBondContact NH2-OH 2.93Å; A410-Y414 PolarHBondContact O-N 2.97Å; V411-Y414 HydrophobicContact CG1-CD1 4.48Å; V411-Y414 WeakPolarHBondContact O-CD1 3.34Å; V411-Y414 PolarHBondContact O-N 3.05Å; Y414-E417 PolarHBondContact O-N 3.39Å; Y414-A418 HydrophobicContact CE2-CB 4.29Å; Y414-A418 WeakPolarHBondContact O-CB 3.43Å; Y414-A418 PolarHBondContact O-N 2.9Å
415	I	98.1	Very high	95.9	Very high	3 Å²	3	38.9 Å²	38.9	2%	0.015	21%	0.213	C	C	.	.	H	α-helix	trans	-63.6	-42.6	178.4	-68.6	165.8	0	0	0	111.2	L351 A354 Q355 V411 Q412 N413 A418 L419	L351-I415 HydrophobicContact CB-CG2 4.17Å; L351-I415 HydrophobicContact CD2-CG1 4.13Å; L351-I415 HydrophobicContact CD2-CG2 4.24Å; L351-I415 WeakPolarHBondContact O-CG2 3.5Å; A354-I415 HydrophobicContact CB-CD1 3.94Å; Q355-I415 HydrophobicContact CB-CG2 3.99Å; Q355-I415 HydrophobicContact CG-CG2 4.33Å; V411-I415 HydrophobicContact CG1-CD1 3.97Å; V411-I415 WeakPolarHBondContact O-CG1 3.44Å; V411-I415 PolarHBondContact O-N 3.48Å; Q412-I415 PolarHBondContact O-N 3.12Å; N413-I415 VanDerWaalsContact C-N 3.33Å; N413-I415 PolarHBondContact O-N 3.29Å; I415-A418 PolarHBondContact O-N 3.43Å; I415-L419 HydrophobicContact CG2-CD1 3.99Å; I415-L419 HydrophobicContact CG2-CG 4.43Å; I415-L419 WeakPolarHBondContact O-CG 3.31Å; I415-L419 PolarHBondContact O-N 3Å
416	K	98	Very high	95.1	Very high	93 Å²	93	41.8 Å²	41.8	40%	0.404	22%	0.222	S	C	.	.	H	α-helix	trans	-57.7	-50.3	174.7	-69.1	167.3	-163.3	164.5	0	111.2	Q412 N413 A418 L419 I420	Q412-K416 VanDerWaalsContact O-CG 3.3Å; Q412-K416 WeakPolarHBondContact O-CG 3.42Å; Q412-K416 PolarHBondContact O-N 3.06Å; N413-K416 PolarHBondContact O-N 3.16Å; N413-K416 PolarHBondContact OD1-NZ 3.43Å; K416-A418 VanDerWaalsContact C-N 3.33Å; K416-A418 PolarHBondContact O-N 2.86Å; K416-L419 PolarHBondContact O-N 3.47Å; K416-I420 WeakPolarHBondContact O-CG1 3.22Å; K416-I420 PolarHBondContact O-N 3.35Å
417	E	97.8	Very high	94	Very high	61 Å²	61	48.7 Å²	48.7	29%	0.285	26%	0.255	S	S	.	.	H	α-helix	trans	-61	-39.6	177.6	-72.4	-65.6	147.4	0	0	112.2	K327 A330 N413 Y414 I420 A421	K327-E417 HydrophobicContact CB-CG 4.02Å; K327-E417 WeakPolarHBondContact CG-OE2 3.29Å; A330-E417 HydrophobicContact CB-CB 3.56Å; N413-E417 PolarHBondContact O-N 3.13Å; Y414-E417 PolarHBondContact O-N 3.39Å; E417-I420 PolarHBondContact O-N 3.23Å; E417-A421 PolarHBondContact O-N 3.02Å
418	A	96.9	Very high	92.3	Very high	0 Å²	0	51.2 Å²	51.2	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-66	-38.5	177	0	0	0	0	0	112.4	A330 L351 Y414 I415 K416 A421 I422	A330-A418 HydrophobicContact CB-CB 3.97Å; L351-A418 HydrophobicContact CD1-CB 3.74Å; L351-A418 HydrophobicContact CD2-CB 4.12Å; Y414-A418 HydrophobicContact CE2-CB 4.29Å; Y414-A418 WeakPolarHBondContact O-CB 3.43Å; Y414-A418 PolarHBondContact O-N 2.9Å; I415-A418 PolarHBondContact O-N 3.43Å; K416-A418 VanDerWaalsContact C-N 3.33Å; K416-A418 PolarHBondContact O-N 2.86Å; A418-A421 PolarHBondContact O-N 3.36Å; A418-I422 VanDerWaalsContact O-CG1 3.27Å; A418-I422 WeakPolarHBondContact O-CG1 3.18Å; A418-I422 PolarHBondContact O-N 2.91Å
419	L	96.6	Very high	90.5	Very high	19 Å²	19	55.2 Å²	55.2	10%	0.099	29%	0.288	C	S	.	.	H	α-helix	trans	-65.1	-41.9	173.3	-69.2	168	0	0	0	111.4	K348 L351 L352 I415 K416 A421 I422 D423	K348-L419 HydrophobicContact CG-CD2 3.89Å; L351-L419 HydrophobicContact CB-CD2 3.88Å; L351-L419 HydrophobicContact CB-CG 4.27Å; L351-L419 HydrophobicContact CD1-CD2 4.28Å; L352-L419 HydrophobicContact CD2-CD1 3.84Å; L352-L419 HydrophobicContact CD2-CD2 4.13Å; L352-L419 HydrophobicContact CG-CD2 4.09Å; I415-L419 HydrophobicContact CG2-CD1 3.99Å; I415-L419 HydrophobicContact CG2-CG 4.43Å; I415-L419 WeakPolarHBondContact O-CG 3.31Å; I415-L419 PolarHBondContact O-N 3Å; K416-L419 PolarHBondContact O-N 3.47Å; L419-A421 VanDerWaalsContact C-N 3.34Å; L419-A421 PolarHBondContact O-N 3.45Å; L419-I422 PolarHBondContact O-N 3.5Å; L419-D423 PolarHBondContact O-N 3.05Å
420	I	95.3	Very high	88.4	Confident	73 Å²	73	55.6 Å²	55.6	37%	0.374	30%	0.3	S	S	.	.	H	α-helix	trans	-60.3	-42.2	174.5	-68.5	164.6	0	0	0	111.3	K416 E417 D423 K424	K416-I420 WeakPolarHBondContact O-CG1 3.22Å; K416-I420 PolarHBondContact O-N 3.35Å; E417-I420 PolarHBondContact O-N 3.23Å; I420-D423 PolarHBondContact O-N 2.9Å; I420-K424 HydrophobicContact CG2-CD 4.09Å; I420-K424 VanDerWaalsContact O-CG 3.31Å; I420-K424 WeakPolarHBondContact O-CG 3.48Å; I420-K424 PolarHBondContact O-N 3.13Å
421	A	92.5	Very high	86.1	Confident	20 Å²	20	61.8 Å²	61.8	17%	0.165	33%	0.332	C	S	.	.	H	α-helix	trans	-64.2	-41.5	177	0	0	0	0	0	112.3	T334 E417 A418 L419 S425	T334-A421 HydrophobicContact CG2-CB 4.35Å; E417-A421 PolarHBondContact O-N 3.02Å; A418-A421 PolarHBondContact O-N 3.36Å; L419-A421 VanDerWaalsContact C-N 3.34Å; L419-A421 PolarHBondContact O-N 3.45Å; A421-S425 PolarHBondContact O-N 2.93Å; A421-S425 VanDerWaalsContact O-N 3.16Å
422	I	93	Very high	83.7	Confident	0 Å²	0	66 Å²	66	0%	0	35%	0.348	C	S	.	.	H	α-helix	trans	-64	-45.7	175.3	-68.3	169	0	0	0	110.9	T334 M344 R347 K348 L351 A418 L419 K424 S425 Y426	T334-I422 HydrophobicContact CG2-CD1 4.41Å; T334-I422 HydrophobicContact CG2-CG1 3.75Å; M344-I422 HydrophobicContact CE-CG1 4.05Å; M344-I422 HydrophobicContact SD-CB 4.23Å; M344-I422 HydrophobicContact SD-CG1 3.8Å; M344-I422 HydrophobicContact SD-CG2 3.95Å; R347-I422 HydrophobicContact CB-CD1 4.48Å; R347-I422 HydrophobicContact CG-CD1 3.91Å; K348-I422 HydrophobicContact CB-CD1 4.33Å; K348-I422 HydrophobicContact CB-CG2 4.3Å; K348-I422 HydrophobicContact CD-CG2 4.2Å; L351-I422 HydrophobicContact CD1-CD1 3.52Å; A418-I422 VanDerWaalsContact O-CG1 3.27Å; A418-I422 WeakPolarHBondContact O-CG1 3.18Å; A418-I422 PolarHBondContact O-N 2.91Å; L419-I422 PolarHBondContact O-N 3.5Å; I422-K424 VanDerWaalsContact C-N 3.34Å; I422-K424 PolarHBondContact O-N 3.13Å; I422-S425 WeakPolarHBondContact O-CB 3.49Å; I422-S425 PolarHBondContact O-N 2.96Å; I422-S425 PolarHBondContact O-OG 3.05Å; I422-Y426 HydrophobicContact CG2-CD2 4.08Å; I422-Y426 HydrophobicContact CG2-CE2 3.53Å; I422-Y426 WeakPolarHBondContact O-CD2 3.48Å; I422-Y426 PolarHBondContact O-N 3.25Å
423	D	91.2	Very high	80.8	Confident	67 Å²	67	69 Å²	69	36%	0.358	37%	0.373	S	S	.	.	H	α-helix	trans	-67.9	-33.5	-178.1	-73.3	-21.4	0	0	0	112.6	K348 L419 I420 S425 Y426 M427	K348-D423 VanDerWaalsContact NZ-CG 3.29Å; K348-D423 IonicContact NZ-OD1 2.74Å; K348-D423 PolarHBondContact NZ-OD1 3.29Å; K348-D423 IonicContact NZ-OD2 3.47Å; K348-D423 PolarHBondContact NZ-OD2 2.98Å; K348-D423 VanDerWaalsContact NZ-OD2 3.14Å; L419-D423 PolarHBondContact O-N 3.05Å; I420-D423 PolarHBondContact O-N 2.9Å; D423-S425 VanDerWaalsContact C-N 3.33Å; D423-S425 PolarHBondContact O-N 3.47Å; D423-Y426 PolarHBondContact O-N 3.42Å; D423-M427 WeakPolarHBondContact O-CG 3.29Å; D423-M427 PolarHBondContact O-N 3.06Å
424	K	89.2	Confident	78.1	Confident	128 Å²	128	72.9 Å²	72.9	56%	0.557	40%	0.4	S	S	*	.	H	α-helix	trans	-61.2	-38	167.7	-74	168.5	-178.9	170.5	0	112.7	I420 I422 Y426 M427 N428	I420-K424 HydrophobicContact CG2-CD 4.09Å; I420-K424 VanDerWaalsContact O-CG 3.31Å; I420-K424 WeakPolarHBondContact O-CG 3.48Å; I420-K424 PolarHBondContact O-N 3.13Å; I422-K424 VanDerWaalsContact C-N 3.34Å; I422-K424 PolarHBondContact O-N 3.13Å; K424-Y426 VanDerWaalsContact C-N 3.3Å; K424-Y426 PolarHBondContact O-N 2.85Å; K424-M427 PolarHBondContact O-N 2.94Å; K424-N428 PolarHBondContact O-N 2.94Å; K424-N428 VanDerWaalsContact O-N 3.16Å
425	S	84.5	Confident	75.5	Confident	40 Å²	40	75.6 Å²	75.6	28%	0.28	43%	0.43	S	S	.	.	H	α-helix	trans	-65.1	-32.1	178	81.2	0	0	0	0	113	A421 I422 D423	A421-S425 PolarHBondContact O-N 2.93Å; A421-S425 VanDerWaalsContact O-N 3.16Å; I422-S425 WeakPolarHBondContact O-CB 3.49Å; I422-S425 PolarHBondContact O-N 2.96Å; I422-S425 PolarHBondContact O-OG 3.05Å; D423-S425 VanDerWaalsContact C-N 3.33Å; D423-S425 PolarHBondContact O-N 3.47Å
426	Y	80.5	Confident	72.7	Confident	78 Å²	78	79.9 Å²	79.9	31%	0.306	45%	0.453	S	S	.	.	H	α-helix	trans	-73.5	-28.1	173.9	-70.3	-59.2	0	0	0	113.4	R341 A345 I422 D423 K424	R341-Y426 HydrophobicContact CG-CE1 4.49Å; A345-Y426 PolarHBondContact N-OH 3.25Å; I422-Y426 HydrophobicContact CG2-CD2 4.08Å; I422-Y426 HydrophobicContact CG2-CE2 3.53Å; I422-Y426 WeakPolarHBondContact O-CD2 3.48Å; I422-Y426 PolarHBondContact O-N 3.25Å; D423-Y426 PolarHBondContact O-N 3.42Å; K424-Y426 VanDerWaalsContact C-N 3.3Å; K424-Y426 PolarHBondContact O-N 2.85Å
427	M	75.6	Confident	70.3	Confident	154 Å²	154	79.9 Å²	79.9	76%	0.759	46%	0.464	S	S	*	.	H	α-helix	trans	-81.8	-16.4	177.1	-64.6	-61	101.7	0	0	113.4	D423 K424 P429	D423-M427 WeakPolarHBondContact O-CG 3.29Å; D423-M427 PolarHBondContact O-N 3.06Å; K424-M427 PolarHBondContact O-N 2.94Å; M427-P429 WeakPolarHBondContact O-CD 3.47Å
428	N	63.5	Low	67.8	Low	97 Å²	97	81.3 Å²	81.3	52%	0.519	48%	0.481	S	S	.	.			trans	-114.2	55.3	179.9	-151.2	43.6	0	0	0	114.2	K424 G430 D431	K424-N428 PolarHBondContact O-N 2.94Å; K424-N428 VanDerWaalsContact O-N 3.16Å; N428-G430 PolarHBondContact O-N 3.35Å; N428-D431 PolarHBondContact ND2-OD2 3.16Å
429	P	59	Low	65.5	Low	104 Å²	104	88.3 Å²	88.3	68%	0.675	51%	0.512	S	S	*	.	G	3₁₀ helix	trans	-72.9	-5.3	178.6	33.4	-36.7	0	0	0	113.8	M427	M427-P429 WeakPolarHBondContact O-CD 3.47Å
430	G	54	Low	63	Low	58 Å²	58	92.1 Å²	92.1	60%	0.598	54%	0.536	S	S	*	.	G	3₁₀ helix	trans	-75.9	-28.3	-171.6	0	0	0	0	0	116	N428	N428-G430 PolarHBondContact O-N 3.35Å
431	D	49.9	Very low	60.9	Low	135 Å²	135	95.6 Å²	95.6	72%	0.722	55%	0.552	S	S	*	*	G	3₁₀ helix	trans	-91.2	4.5	-173.4	-75.6	-37.5	0	0	0	114.5	N428	N428-D431 PolarHBondContact ND2-OD2 3.16Å
432	Q	49.3	Very low	58.9	Low	151 Å²	151	102.5 Å²	102.5	71%	0.706	58%	0.581	S	S	*	*	G	3₁₀ helix	trans	-109.7	26	176	-67.4	-166	41.8	0	0	113.8
433	S	35.8	Very low	56.9	Low	96 Å²	96	111.2 Å²	111.2	67%	0.671	62%	0.619	S	S	*	*	S	Bend	trans	-73.4	131.2	154.7	-83.8	0	0	0	0	108.9	A435	S433-A435 PolarHBondContact O-N 3.09Å; S433-A435 VanDerWaalsContact O-N 3.13Å
434	P	42.6	Very low	55.1	Low	117 Å²	117	114.9 Å²	114.9	76%	0.76	64%	0.636	S	S	*	*	P	Polyproline II helix	trans	-61.2	120.7	165.3	27.5	-32	0	0	0	107.4	D436	P434-D436 PolarHBondContact O-N 3.29Å
435	A	42.3	Very low	53.4	Low	94 Å²	94	116 Å²	116	78%	0.777	64%	0.643	S	S	*	*	P	Polyproline II helix	trans	-53.6	127.2	176.8	0	0	0	0	0	109.3	S433 S437	S433-A435 PolarHBondContact O-N 3.09Å; S433-A435 VanDerWaalsContact O-N 3.13Å; A435-S437 VanDerWaalsContact C-N 3.34Å; A435-S437 PolarHBondContact O-N 3.33Å
436	D	40.4	Very low	51.9	Low	93 Å²	93	123.3 Å²	123.3	50%	0.497	67%	0.67	S	S	.	*			trans	-46.1	85.4	-170.9	-84	-46.4	0	0	0	113.7	P434 S438 K439	P434-D436 PolarHBondContact O-N 3.29Å; D436-S438 PolarHBondContact O-N 3.28Å; D436-K439 HydrophobicContact CB-CB 4.14Å; D436-K439 HydrophobicContact CB-CD 3.92Å; D436-K439 HydrophobicContact CB-CG 4.06Å; D436-K439 PolarHBondContact O-N 3.28Å; D436-K439 VanDerWaalsContact O-N 3.13Å; D436-K439 WeakPolarHBondContact OD2-CD 3.01Å; D436-K439 WeakPolarHBondContact OD2-CE 3.41Å; D436-K439 IonicContact OD2-NZ 2.67Å; D436-K439 PolarHBondContact OD2-NZ 3.03Å
437	S	46.2	Very low	50.7	Low	92 Å²	92	128.3 Å²	128.3	64%	0.643	70%	0.696	S	S	*	*	T	Hydrogen-bonded Turn	trans	-65.3	-22.2	174	49	0	0	0	0	111.5	A435 K439	A435-S437 VanDerWaalsContact C-N 3.34Å; A435-S437 PolarHBondContact O-N 3.33Å; S437-K439 PolarHBondContact O-N 3.29Å
438	S	45.8	Very low	49.6	Very low	91 Å²	91	131.9 Å²	131.9	64%	0.636	70%	0.701	S	S	*	*	H	α-helix	trans	-67.2	-25.5	173.1	-56.4	0	0	0	0	114.4	D436	D436-S438 PolarHBondContact O-N 3.28Å
439	K	47.7	Very low	49	Very low	147 Å²	147	140.8 Å²	140.8	64%	0.639	73%	0.734	S	S	*	*	H	α-helix	trans	-83.9	-10.9	-178.9	-75.4	175.9	-175.8	150.9	0	114.1	D436 S437	D436-K439 HydrophobicContact CB-CB 4.14Å; D436-K439 HydrophobicContact CB-CD 3.92Å; D436-K439 HydrophobicContact CB-CG 4.06Å; D436-K439 PolarHBondContact O-N 3.28Å; D436-K439 VanDerWaalsContact O-N 3.13Å; D436-K439 WeakPolarHBondContact OD2-CD 3.01Å; D436-K439 WeakPolarHBondContact OD2-CE 3.41Å; D436-K439 IonicContact OD2-NZ 2.67Å; D436-K439 PolarHBondContact OD2-NZ 3.03Å; S437-K439 PolarHBondContact O-N 3.29Å
440	T	46	Very low	48.5	Very low	99 Å²	99	142.6 Å²	142.6	61%	0.607	74%	0.737	S	S	*	*	H	α-helix	trans	-96.9	-26.3	-179.8	-41.4	0	0	0	0	112.7
441	M	49.3	Very low	48.2	Very low	147 Å²	147	147.1 Å²	147.1	72%	0.724	75%	0.745	S	S	*	*	H	α-helix	trans	-71.7	-42	174.5	-90.9	-175.3	63.5	0	0	113	K443 M444	M441-K443 PolarHBondContact O-N 3.3Å; M441-M444 PolarHBondContact O-N 3.36Å
442	E	50.5	Low	48.1	Very low	165 Å²	165	147.7 Å²	147.7	77%	0.771	75%	0.746	S	S	*	*	T	Hydrogen-bonded Turn	trans	-64.8	-17.4	-175.5	-128.1	-171.6	150.8	0	0	113.9
443	K	52.4	Low	48.1	Very low	183 Å²	183	147.5 Å²	147.5	80%	0.796	75%	0.748	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.9	-9.8	177.8	-128.2	176.2	-175.4	178.7	0	114.2	M441	M441-K443 PolarHBondContact O-N 3.3Å
444	M	52.1	Low	48.8	Very low	143 Å²	143	150.8 Å²	150.8	70%	0.704	75%	0.753	S	S	*	*	T	Hydrogen-bonded Turn	trans	-100.2	-24.7	-178.4	-142.9	174.9	-66.4	0	0	113.2	M441 K446	M441-M444 PolarHBondContact O-N 3.36Å; M444-K446 PolarHBondContact O-N 3.25Å
445	E	54.1	Low	49.3	Very low	152 Å²	152	153 Å²	153	71%	0.71	75%	0.753	S	S	*	*	G	3₁₀ helix	trans	-67.8	-21.3	177.2	-153.6	66.7	-144.7	0	0	113	H447	E445-H447 VanDerWaalsContact C-N 3.33Å; E445-H447 PolarHBondContact O-N 3.32Å
446	K	52.7	Low	49.8	Very low	194 Å²	194	157.2 Å²	157.2	84%	0.843	75%	0.751	S	S	*	*	G	3₁₀ helix	trans	-85	2.7	-173.6	-125.6	172.8	-172.8	171.1	0	115.4	M444	M444-K446 PolarHBondContact O-N 3.25Å
447	H	56.6	Low	50.5	Low	183 Å²	183	162.2 Å²	162.2	85%	0.847	77%	0.771	S	S	*	*	G	3₁₀ helix	trans	-116.2	13.5	179.3	-108.9	-64.6	0	0	0	114.4	E445	E445-H447 VanDerWaalsContact C-N 3.33Å; E445-H447 PolarHBondContact O-N 3.32Å
448	R	51.2	Low	50.8	Low	229 Å²	229	168 Å²	168	86%	0.864	78%	0.781	S	S	*	*			trans	-127.5	80.7	177.5	-167.3	174.8	-176.4	157.5	0.8	111.3
449	K	51.8	Low	51.3	Low	283 Å²	283	175 Å²	175	100%	1.23	79%	0.794	S	S	*	*			trans	-144.3	0	169	-123.1	-175.8	-177.4	-177	0	110.1

Retrieved 449 of 449 residues in 470.4 ms (Link to these results)

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