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Protein cornichon homolog 2

Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors.

AlphaFold DB , UniProt , Accession Q6PI25, Species HUMAN (Homo sapiens, Human), Gene CNIH2, Length 160 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M53.6Low83.4Confident201 Ų20165.1 Ų65.199%0.9934%0.335SS*.  084.10-54-153.7-65.500107.2F3M1-F3 PolarHBondContact O-N 3.49Å
2A58.3Low84.4Confident74 Ų7465.3 Ų65.361%0.61234%0.337SS*.  trans-70.3118.4169.600000105.8T4 F160A2-T4 VanDerWaalsContact C-N 3.31Å; A2-T4 WeakPolarHBondContact O-CG2 3.47Å; A2-T4 PolarHBondContact O-N 3.18Å; A2-F160 PolarHBondContact N-O 3.3Å
3F73.4Confident85.3Confident122 Ų12260.3 Ų60.354%0.53531%0.311SS..  trans-63.398.6174.6-175-109.1000107.9M1 A7 F8 M11M1-F3 PolarHBondContact O-N 3.49Å; F3-A7 HydrophobicContact CE2-CB 4.42Å; F3-F8 HydrophobicContact CD1-CB 4.48Å; F3-F8 HydrophobicContact CE1-CB 3.5Å; F3-F8 AromaticContact CE1-CD2 3.79Å; F3-F8 HydrophobicContact CE1-CD2 3.79Å; F3-F8 HydrophobicContact CE1-CG 4.04Å; F3-F8 HydrophobicContact CZ-CB 3.65Å; F3-F8 AromaticContact CZ-CD2 3.88Å; F3-F8 HydrophobicContact CZ-CD2 3.88Å; F3-F8 HydrophobicContact CZ-CG 4.26Å; F3-M11 HydrophobicContact CE2-CE 3.76Å; F3-M11 HydrophobicContact CE2-SD 3.72Å; F3-M11 HydrophobicContact CZ-SD 3.97Å
4T85.9Confident86.1Confident33 Ų3357.8 Ų57.820%0.20230%0.298CS..  trans-72.4149.6-176.262.80000109.3A2 A6 A7 F8 F160A2-T4 VanDerWaalsContact C-N 3.31Å; A2-T4 WeakPolarHBondContact O-CG2 3.47Å; A2-T4 PolarHBondContact O-N 3.18Å; T4-A6 PolarHBondContact O-N 2.82Å; T4-A7 PolarHBondContact O-N 3.24Å; T4-A7 VanDerWaalsContact O-N 3.12Å; T4-A7 WeakPolarHBondContact OG1-CB 3.43Å; T4-A7 PolarHBondContact OG1-N 3.38Å; T4-F8 PolarHBondContact O-N 2.97Å; T4-F160 HydrophobicContact CG2-CB 3.82Å; T4-F160 HydrophobicContact CG2-CD2 4.34Å; T4-F160 HydrophobicContact CG2-CG 4.06Å
5F89.9Confident86.8Confident112 Ų11260.7 Ų60.749%0.49132%0.319SS..Hα-helixtrans-55.9-36.7172.6178.9-117000111.3F8 C9 C84 A85F5-F8 WeakPolarHBondContact O-CB 3.45Å; F5-F8 PolarHBondContact O-N 3.23Å; F5-C9 PolarHBondContact O-N 3.19Å; F5-C9 PolarHBondContact O-SG 3.28Å; F5-C84 HydrophobicContact CE1-CB 3.98Å; F5-C84 HydrophobicContact CZ-CB 4.23Å; F5-A85 HydrophobicContact CD1-CB 3.92Å; F5-A85 HydrophobicContact CE1-CB 3.89Å
6A90.3Very high87.4Confident14 Ų1458.8 Ų58.812%0.11631%0.309CS..Hα-helixtrans-59.2-47.3174.400000112.7T4 F8 C9 Y10 E87T4-A6 PolarHBondContact O-N 2.82Å; A6-F8 VanDerWaalsContact C-N 3.31Å; A6-F8 PolarHBondContact O-N 3.06Å; A6-C9 WeakPolarHBondContact O-CB 3.43Å; A6-C9 PolarHBondContact O-N 3.38Å; A6-C9 VanDerWaalsContact O-N 3.1Å; A6-Y10 WeakPolarHBondContact O-CD2 3.39Å; A6-Y10 PolarHBondContact O-N 3.42Å; A6-E87 HydrophobicContact CB-CG 4.42Å
7A91.4Very high87.9Confident0 Ų055.4 Ų55.40%029%0.291CS..Hα-helixtrans-59.9-41.4177.500000111.8F3 T4 C9 Y10 M11 L157F3-A7 HydrophobicContact CE2-CB 4.42Å; T4-A7 PolarHBondContact O-N 3.24Å; T4-A7 VanDerWaalsContact O-N 3.12Å; T4-A7 WeakPolarHBondContact OG1-CB 3.43Å; T4-A7 PolarHBondContact OG1-N 3.38Å; A7-C9 PolarHBondContact O-N 2.98Å; A7-Y10 PolarHBondContact O-N 3.33Å; A7-M11 WeakPolarHBondContact O-CG 3.49Å; A7-M11 PolarHBondContact O-N 3.26Å; A7-L157 HydrophobicContact CB-CD2 3.75Å; A7-L157 HydrophobicContact CB-CG 4.18Å
8F91.9Very high88.4Confident92 Ų9254.1 Ų54.140%0.40429%0.289SS..Hα-helixtrans-58.4-46.6172.5180-106.5000112.1F3 T4 F5 A6 Y10 M11 L12F3-F8 HydrophobicContact CD1-CB 4.48Å; F3-F8 HydrophobicContact CE1-CB 3.5Å; F3-F8 AromaticContact CE1-CD2 3.79Å; F3-F8 HydrophobicContact CE1-CD2 3.79Å; F3-F8 HydrophobicContact CE1-CG 4.04Å; F3-F8 HydrophobicContact CZ-CB 3.65Å; F3-F8 AromaticContact CZ-CD2 3.88Å; F3-F8 HydrophobicContact CZ-CD2 3.88Å; F3-F8 HydrophobicContact CZ-CG 4.26Å; T4-F8 PolarHBondContact O-N 2.97Å; F5-F8 WeakPolarHBondContact O-CB 3.45Å; F5-F8 PolarHBondContact O-N 3.23Å; A6-F8 VanDerWaalsContact C-N 3.31Å; A6-F8 PolarHBondContact O-N 3.06Å; F8-Y10 VanDerWaalsContact C-N 3.32Å; F8-Y10 PolarHBondContact O-N 3.12Å; F8-M11 PolarHBondContact O-N 3.26Å; F8-L12 HydrophobicContact CE1-CD2 4.48Å; F8-L12 PolarHBondContact O-N 3.26Å
9C94.2Very high88.8Confident0 Ų053.1 Ų53.10%029%0.287CS..Hα-helixtrans-59.3-43.4178.1-63.20000111.5F5 A6 A7 T13 M81 F82 A85F5-C9 PolarHBondContact O-N 3.19Å; F5-C9 PolarHBondContact O-SG 3.28Å; A6-C9 WeakPolarHBondContact O-CB 3.43Å; A6-C9 PolarHBondContact O-N 3.38Å; A6-C9 VanDerWaalsContact O-N 3.1Å; A7-C9 PolarHBondContact O-N 2.98Å; C9-T13 VanDerWaalsContact O-CB 3.28Å; C9-T13 WeakPolarHBondContact O-CB 3.43Å; C9-T13 PolarHBondContact O-N 3.36Å; C9-T13 PolarHBondContact O-OG1 2.63Å; C9-M81 HydrophobicContact CB-CE 3.87Å; C9-M81 HydrophobicContact CB-CG 3.81Å; C9-M81 HydrophobicContact CB-SD 3.93Å; C9-M81 WeakPolarHBondContact O-CE 3.46Å; C9-M81 WeakPolarHBondContact SG-CG 3.44Å; C9-F82 HydrophobicContact CB-CD1 4.49Å; C9-F82 HydrophobicContact CB-CE1 4.44Å; C9-A85 HydrophobicContact CB-CB 4.38Å
10Y94.9Very high89.2Confident2 Ų250.5 Ų50.51%0.00827%0.273CS..Hα-helixtrans-65.3-41.7176.3-75.2-67.9000113.2A6 A7 F8 T13 L14 F82 E87 T90 S152 M153 T156A6-Y10 WeakPolarHBondContact O-CD2 3.39Å; A6-Y10 PolarHBondContact O-N 3.42Å; A7-Y10 PolarHBondContact O-N 3.33Å; F8-Y10 VanDerWaalsContact C-N 3.32Å; F8-Y10 PolarHBondContact O-N 3.12Å; Y10-T13 PolarHBondContact O-N 3Å; Y10-L14 WeakPolarHBondContact O-CG 3.31Å; Y10-L14 PolarHBondContact O-N 3.12Å; Y10-F82 AromaticContact CD1-CE1 3.7Å; Y10-F82 HydrophobicContact CD1-CE1 3.7Å; Y10-F82 AromaticContact CD1-CZ 3.93Å; Y10-F82 HydrophobicContact CD1-CZ 3.93Å; Y10-F82 AromaticContact CE1-CE1 3.57Å; Y10-F82 HydrophobicContact CE1-CE1 3.57Å; Y10-F82 AromaticContact CE1-CZ 3.92Å; Y10-F82 HydrophobicContact CE1-CZ 3.92Å; Y10-F82 HydrophobicContact CG-CE1 4.28Å; Y10-E87 HydrophobicContact CE2-CG 4.09Å; Y10-E87 VanDerWaalsContact OH-CD 3.3Å; Y10-E87 PolarHBondContact OH-OE2 3.05Å; Y10-T90 HydrophobicContact CE1-CG2 3.83Å; Y10-T90 WeakPolarHBondContact OH-CG2 3.39Å; Y10-S152 VanDerWaalsContact CZ-CB 3.42Å; Y10-M153 HydrophobicContact CG-CB 4.48Å; Y10-T156 HydrophobicContact CD2-CG2 4.09Å; Y10-T156 HydrophobicContact CE2-CG2 3.74Å
11M93.8Very high89.5Confident66 Ų6649.3 Ų49.333%0.32527%0.266SS..Hα-helixtrans-60.7-47.1176.8-72.3-178.6-174.700111.8F3 A7 F8 L14 V15 M153 L157F3-M11 HydrophobicContact CE2-CE 3.76Å; F3-M11 HydrophobicContact CE2-SD 3.72Å; F3-M11 HydrophobicContact CZ-SD 3.97Å; A7-M11 WeakPolarHBondContact O-CG 3.49Å; A7-M11 PolarHBondContact O-N 3.26Å; F8-M11 PolarHBondContact O-N 3.26Å; M11-L14 PolarHBondContact O-N 3.04Å; M11-V15 PolarHBondContact O-N 2.97Å; M11-M153 HydrophobicContact CE-CE 4.36Å; M11-M153 HydrophobicContact CE-SD 4.45Å; M11-M153 HydrophobicContact CG-CG 4.03Å; M11-M153 HydrophobicContact CG-SD 3.74Å; M11-L157 HydrophobicContact CE-CD1 3.69Å; M11-L157 HydrophobicContact CE-CD2 4.04Å; M11-L157 HydrophobicContact CE-CG 4.35Å
12L94.9Very high91.6Very high68 Ų6846.9 Ų46.936%0.35625%0.251SS..Hα-helixtrans-66.5-42.6178-176.162000111.2F8 L14 V15 L16 M81F8-L12 HydrophobicContact CE1-CD2 4.48Å; F8-L12 PolarHBondContact O-N 3.26Å; L12-L14 VanDerWaalsContact C-N 3.3Å; L12-L14 PolarHBondContact O-N 3.45Å; L12-V15 PolarHBondContact O-N 3.1Å; L12-L16 HydrophobicContact CD1-CG 4.43Å; L12-L16 HydrophobicContact CG-CD1 4.04Å; L12-L16 HydrophobicContact CG-CG 4.36Å; L12-L16 WeakPolarHBondContact O-CG 3.32Å; L12-L16 PolarHBondContact O-N 2.99Å; L12-M81 HydrophobicContact CB-CE 4.11Å; L12-M81 HydrophobicContact CB-SD 4.31Å; L12-M81 HydrophobicContact CD2-CE 4.27Å; L12-M81 HydrophobicContact CD2-SD 3.75Å; L12-M81 HydrophobicContact CG-CE 4.38Å; L12-M81 HydrophobicContact CG-SD 4.44Å
13T96.1Very high93.3Very high0 Ų046.2 Ų46.20%023%0.234CC..Hα-helixtrans-60.4-37.9176.7-63.90000112C9 Y10 V15 L16 C17 F78 M81 F82 Y149C9-T13 VanDerWaalsContact O-CB 3.28Å; C9-T13 WeakPolarHBondContact O-CB 3.43Å; C9-T13 PolarHBondContact O-N 3.36Å; C9-T13 PolarHBondContact O-OG1 2.63Å; Y10-T13 PolarHBondContact O-N 3Å; T13-V15 VanDerWaalsContact C-N 3.33Å; T13-V15 PolarHBondContact O-N 2.95Å; T13-L16 PolarHBondContact O-N 3.05Å; T13-C17 WeakPolarHBondContact O-CA 3.3Å; T13-C17 WeakPolarHBondContact O-CB 3.39Å; T13-C17 PolarHBondContact O-N 3.24Å; T13-F78 HydrophobicContact CG2-CB 4.28Å; T13-F78 HydrophobicContact CG2-CD2 4.09Å; T13-F78 HydrophobicContact CG2-CG 4.11Å; T13-M81 WeakPolarHBondContact OG1-CE 3.38Å; T13-F82 HydrophobicContact CG2-CE2 3.72Å; T13-F82 HydrophobicContact CG2-CZ 3.68Å; T13-F82 WeakPolarHBondContact OG1-CZ 3.1Å; T13-Y149 HydrophobicContact CG2-CD2 3.55Å; T13-Y149 HydrophobicContact CG2-CE2 3.57Å; T13-Y149 HydrophobicContact CG2-CG 4.09Å
14L96.4Very high94.4Very high25 Ų2540.4 Ų40.413%0.13121%0.209CC..Hα-helixtrans-60.1-43.7176.7-81168.2000112.1Y10 M11 L12 A18 F146 L150 M153Y10-L14 WeakPolarHBondContact O-CG 3.31Å; Y10-L14 PolarHBondContact O-N 3.12Å; M11-L14 PolarHBondContact O-N 3.04Å; L12-L14 VanDerWaalsContact C-N 3.3Å; L12-L14 PolarHBondContact O-N 3.45Å; L14-A18 WeakPolarHBondContact O-CB 3.49Å; L14-A18 PolarHBondContact O-N 3.08Å; L14-F146 HydrophobicContact CD2-CD2 3.95Å; L14-F146 HydrophobicContact CD2-CE2 3.79Å; L14-F146 HydrophobicContact CD2-CZ 4.24Å; L14-L150 HydrophobicContact CD2-CB 4.16Å; L14-M153 HydrophobicContact CD1-CB 4.17Å; L14-M153 HydrophobicContact CD1-CG 4.34Å; L14-M153 HydrophobicContact CD1-SD 3.61Å
15V96.4Very high94.9Very high101 Ų10142.2 Ų42.261%0.61222%0.216SC*.Hα-helixtrans-65.7-45.6176.81790000110.9M11 L12 T13 A18 S19M11-V15 PolarHBondContact O-N 2.97Å; L12-V15 PolarHBondContact O-N 3.1Å; T13-V15 VanDerWaalsContact C-N 3.33Å; T13-V15 PolarHBondContact O-N 2.95Å; V15-A18 PolarHBondContact O-N 2.79Å; V15-S19 PolarHBondContact O-N 2.89Å
16L96.6Very high95.2Very high31 Ų3141.3 Ų41.316%0.16221%0.21CC..Hα-helixtrans-65.1-40178-67178.9000112L12 T13 S19 L20 I74 L77 F78L12-L16 HydrophobicContact CD1-CG 4.43Å; L12-L16 HydrophobicContact CG-CD1 4.04Å; L12-L16 HydrophobicContact CG-CG 4.36Å; L12-L16 WeakPolarHBondContact O-CG 3.32Å; L12-L16 PolarHBondContact O-N 2.99Å; T13-L16 PolarHBondContact O-N 3.05Å; L16-S19 PolarHBondContact O-N 3.24Å; L16-S19 PolarHBondContact O-OG 2.98Å; L16-L20 WeakPolarHBondContact O-CG 3.4Å; L16-L20 PolarHBondContact O-N 3.17Å; L16-I74 HydrophobicContact CB-CG2 3.84Å; L16-I74 HydrophobicContact CD1-CG2 4.44Å; L16-I74 HydrophobicContact CD2-CG2 4.06Å; L16-I74 HydrophobicContact CG-CG2 4.32Å; L16-L77 HydrophobicContact CD1-CD2 4.29Å; L16-F78 HydrophobicContact CD1-CB 4.25Å
17C96.7Very high95.4Very high0 Ų040.8 Ų40.80%021%0.205CC..Hα-helixtrans-65-42.6177.1-174.90000111T13 S19 L20 I21 F146 Y149T13-C17 WeakPolarHBondContact O-CA 3.3Å; T13-C17 WeakPolarHBondContact O-CB 3.39Å; T13-C17 PolarHBondContact O-N 3.24Å; C17-S19 VanDerWaalsContact C-N 3.3Å; C17-S19 PolarHBondContact O-N 3.49Å; C17-L20 WeakPolarHBondContact O-CB 3.4Å; C17-L20 PolarHBondContact O-N 3.31Å; C17-L20 VanDerWaalsContact O-N 3.16Å; C17-I21 WeakPolarHBondContact O-CG1 3.5Å; C17-I21 PolarHBondContact O-N 3.47Å; C17-F146 HydrophobicContact CB-CD2 4.38Å; C17-Y149 HydrophobicContact CB-CD2 4.19Å; C17-Y149 HydrophobicContact CB-CE2 4.24Å
18A96.4Very high95.6Very high32 Ų3241.6 Ų41.626%0.26421%0.209SC..Hα-helixtrans-58.6-42.8172.300000111.6L14 V15 L20 I21 F22 F146L14-A18 WeakPolarHBondContact O-CB 3.49Å; L14-A18 PolarHBondContact O-N 3.08Å; V15-A18 PolarHBondContact O-N 2.79Å; A18-L20 VanDerWaalsContact C-N 3.33Å; A18-L20 PolarHBondContact O-N 2.93Å; A18-I21 PolarHBondContact O-N 2.66Å; A18-F22 WeakPolarHBondContact O-CD2 3.34Å; A18-F22 PolarHBondContact O-N 3.18Å; A18-F146 HydrophobicContact CB-CE2 4.39Å
19S95.9Very high95.8Very high36 Ų3642 Ų4225%0.25222%0.215SC..Hα-helixtrans-62.5-38.6175.6790000112.9V15 L16 C17 F22 F23V15-S19 PolarHBondContact O-N 2.89Å; L16-S19 PolarHBondContact O-N 3.24Å; L16-S19 PolarHBondContact O-OG 2.98Å; C17-S19 VanDerWaalsContact C-N 3.3Å; C17-S19 PolarHBondContact O-N 3.49Å; S19-F22 PolarHBondContact O-N 3.24Å; S19-F23 PolarHBondContact O-N 3.25Å; S19-F23 VanDerWaalsContact O-N 3.07Å
20L96.3Very high95.7Very high0 Ų042.2 Ų42.20%022%0.216CC..Hα-helixtrans-66.6-38.7175.5-75.9172.7000112.3L16 C17 A18 F22 F23 V24 E71 I74 F78 Y142L16-L20 WeakPolarHBondContact O-CG 3.4Å; L16-L20 PolarHBondContact O-N 3.17Å; C17-L20 WeakPolarHBondContact O-CB 3.4Å; C17-L20 PolarHBondContact O-N 3.31Å; C17-L20 VanDerWaalsContact O-N 3.16Å; A18-L20 VanDerWaalsContact C-N 3.33Å; A18-L20 PolarHBondContact O-N 2.93Å; L20-F22 VanDerWaalsContact C-N 3.29Å; L20-F22 PolarHBondContact O-N 2.97Å; L20-F23 PolarHBondContact O-N 2.99Å; L20-V24 WeakPolarHBondContact O-CG2 3.3Å; L20-V24 PolarHBondContact O-N 3.13Å; L20-E71 HydrophobicContact CD2-CB 4.28Å; L20-E71 HydrophobicContact CD2-CG 3.68Å; L20-I74 HydrophobicContact CD1-CB 4.44Å; L20-I74 HydrophobicContact CD1-CG2 3.84Å; L20-I74 HydrophobicContact CD2-CB 4.01Å; L20-I74 HydrophobicContact CD2-CD1 4.45Å; L20-I74 HydrophobicContact CD2-CG2 4.1Å; L20-I74 HydrophobicContact CG-CB 4.29Å; L20-I74 HydrophobicContact CG-CG2 3.81Å; L20-F78 HydrophobicContact CD1-CD1 4.33Å; L20-F78 HydrophobicContact CD1-CE1 3.59Å; L20-Y142 HydrophobicContact CB-CD2 4.38Å; L20-Y142 HydrophobicContact CB-CE2 4.25Å; L20-Y142 HydrophobicContact CD1-CD1 4.45Å; L20-Y142 HydrophobicContact CD1-CE1 3.86Å
21I96.9Very high95.6Very high26 Ų2642.1 Ų42.113%0.13322%0.216CC..Hα-helixtrans-58.1-45.1174-69.8168000109.9C17 A18 F23 V24 I25 L139 F146C17-I21 WeakPolarHBondContact O-CG1 3.5Å; C17-I21 PolarHBondContact O-N 3.47Å; A18-I21 PolarHBondContact O-N 2.66Å; I21-F23 PolarHBondContact O-N 3.31Å; I21-V24 PolarHBondContact O-N 2.84Å; I21-I25 HydrophobicContact CG2-CD1 3.73Å; I21-I25 HydrophobicContact CG2-CG1 4.4Å; I21-I25 VanDerWaalsContact O-CG1 3.26Å; I21-I25 WeakPolarHBondContact O-CG1 3.47Å; I21-I25 PolarHBondContact O-N 3.03Å; I21-L139 HydrophobicContact CG2-CD1 4.2Å; I21-F146 HydrophobicContact CD1-CB 4.2Å; I21-F146 HydrophobicContact CD1-CD2 4.32Å; I21-F146 HydrophobicContact CD1-CG 4.35Å
22F96.4Very high95.6Very high150 Ų15043 Ų4366%0.65822%0.221SC*.Hα-helixtrans-60.7-43.4175.1-75.3-67.3000112.7A18 S19 L20 I25 W26A18-F22 WeakPolarHBondContact O-CD2 3.34Å; A18-F22 PolarHBondContact O-N 3.18Å; S19-F22 PolarHBondContact O-N 3.24Å; L20-F22 VanDerWaalsContact C-N 3.29Å; L20-F22 PolarHBondContact O-N 2.97Å; F22-I25 PolarHBondContact O-N 3.41Å; F22-W26 PolarHBondContact O-N 3.01Å
23F95Very high95.5Very high60 Ų6044.2 Ų44.226%0.26323%0.226SC..Hα-helixtrans-63.3-41.5176.6-69.5-12.1000112.5S19 L20 I21 W26 H27 L67 P70 I74S19-F23 PolarHBondContact O-N 3.25Å; S19-F23 VanDerWaalsContact O-N 3.07Å; L20-F23 PolarHBondContact O-N 2.99Å; I21-F23 PolarHBondContact O-N 3.31Å; F23-W26 PolarHBondContact O-N 3.46Å; F23-H27 PolarHBondContact O-N 3.49Å; F23-H27 PolarHBondContact O-ND1 2.95Å; F23-L67 HydrophobicContact CB-CD2 4.25Å; F23-L67 HydrophobicContact CD1-CD1 4.01Å; F23-L67 HydrophobicContact CD1-CD2 4.27Å; F23-L67 HydrophobicContact CD1-CG 4.48Å; F23-L67 HydrophobicContact CD2-CD1 4.34Å; F23-L67 HydrophobicContact CE1-CD1 4.01Å; F23-L67 HydrophobicContact CE2-CD1 4.34Å; F23-L67 HydrophobicContact CG-CD1 4.19Å; F23-L67 HydrophobicContact CG-CD2 4.32Å; F23-L67 HydrophobicContact CG-CG 4.33Å; F23-L67 HydrophobicContact CZ-CD1 4.18Å; F23-P70 HydrophobicContact CE2-CB 4.4Å; F23-I74 HydrophobicContact CD2-CD1 4.33Å; F23-I74 HydrophobicContact CE2-CD1 3.71Å
24V95.8Very high95.2Very high1 Ų144.8 Ų44.81%0.00623%0.228CC..Hα-helixtrans-69-38.9178175.90000111.8L20 I21 W26 H27 I28 S135 K138 L139 Y142L20-V24 WeakPolarHBondContact O-CG2 3.3Å; L20-V24 PolarHBondContact O-N 3.13Å; I21-V24 PolarHBondContact O-N 2.84Å; V24-W26 VanDerWaalsContact C-N 3.28Å; V24-W26 PolarHBondContact O-N 2.86Å; V24-H27 WeakPolarHBondContact O-CB 3.32Å; V24-H27 PolarHBondContact O-N 3.37Å; V24-I28 HydrophobicContact CG1-CD1 4.1Å; V24-I28 HydrophobicContact CG1-CG1 4.48Å; V24-I28 WeakPolarHBondContact O-CG1 3.06Å; V24-I28 PolarHBondContact O-N 3.35Å; V24-S135 VanDerWaalsContact CG1-O 3.29Å; V24-S135 WeakPolarHBondContact CG1-O 3.36Å; V24-K138 HydrophobicContact CG1-CB 4.3Å; V24-K138 HydrophobicContact CG2-CB 4.3Å; V24-L139 HydrophobicContact CG1-CB 3.71Å; V24-L139 HydrophobicContact CG1-CD1 4.34Å; V24-Y142 HydrophobicContact CG2-CD2 3.69Å; V24-Y142 HydrophobicContact CG2-CE2 3.54Å
25I96.8Very high94.8Very high70 Ų7047.5 Ų47.536%0.35924%0.237SC..Hα-helixtrans-59.4-44173.8-69.7167.2000110.2I21 F22 H27 I28 I29 L139I21-I25 HydrophobicContact CG2-CD1 3.73Å; I21-I25 HydrophobicContact CG2-CG1 4.4Å; I21-I25 VanDerWaalsContact O-CG1 3.26Å; I21-I25 WeakPolarHBondContact O-CG1 3.47Å; I21-I25 PolarHBondContact O-N 3.03Å; F22-I25 PolarHBondContact O-N 3.41Å; I25-H27 VanDerWaalsContact C-N 3.34Å; I25-H27 PolarHBondContact O-N 2.92Å; I25-I28 PolarHBondContact O-N 3.19Å; I25-I29 HydrophobicContact CG2-CD1 3.92Å; I25-I29 WeakPolarHBondContact O-CG1 3.34Å; I25-I29 PolarHBondContact O-N 3.2Å; I25-L139 HydrophobicContact CG1-CD1 4.04Å
26W95.9Very high94.4Very high94 Ų9446.1 Ų46.136%0.35623%0.229SC..Hα-helixtrans-61-41.8175.8-174.788.7000112.2F22 F23 V24 I28 I29 A30 L63 L64 L67F22-W26 PolarHBondContact O-N 3.01Å; F23-W26 PolarHBondContact O-N 3.46Å; V24-W26 VanDerWaalsContact C-N 3.28Å; V24-W26 PolarHBondContact O-N 2.86Å; W26-I28 PolarHBondContact O-N 3.47Å; W26-I29 PolarHBondContact O-N 2.87Å; W26-A30 HydrophobicContact CH2-CB 4.45Å; W26-A30 HydrophobicContact CZ3-CB 4.45Å; W26-A30 WeakPolarHBondContact O-CB 3.32Å; W26-A30 PolarHBondContact O-N 2.89Å; W26-L63 HydrophobicContact CH2-CB 3.44Å; W26-L63 VanDerWaalsContact CH2-CB 3.44Å; W26-L63 HydrophobicContact CZ2-CB 3.87Å; W26-L63 HydrophobicContact CZ2-CD1 4.12Å; W26-L64 HydrophobicContact CE3-CD2 4.39Å; W26-L64 HydrophobicContact CH2-CD2 4.29Å; W26-L64 HydrophobicContact CH2-CG 4.27Å; W26-L64 HydrophobicContact CZ3-CD2 3.66Å; W26-L64 HydrophobicContact CZ3-CG 4.07Å; W26-L67 HydrophobicContact CD2-CD2 3.91Å; W26-L67 HydrophobicContact CE3-CD2 3.22Å; W26-L67 HydrophobicContact CG-CD2 4.48Å; W26-L67 HydrophobicContact CZ3-CB 4.33Å; W26-L67 HydrophobicContact CZ3-CD2 3.68Å
27H94.2Very high93.8Very high2 Ų246 Ų461%0.00923%0.228CC..Hα-helixtrans-59.2-44.7173.2-74.8102.9000112.1F23 V24 I25 I29 A30 F31 L64 E71F23-H27 PolarHBondContact O-N 3.49Å; F23-H27 PolarHBondContact O-ND1 2.95Å; V24-H27 WeakPolarHBondContact O-CB 3.32Å; V24-H27 PolarHBondContact O-N 3.37Å; I25-H27 VanDerWaalsContact C-N 3.34Å; I25-H27 PolarHBondContact O-N 2.92Å; H27-I29 PolarHBondContact O-N 3.41Å; H27-A30 PolarHBondContact O-N 2.87Å; H27-F31 HydrophobicContact CB-CD2 4.47Å; H27-F31 HydrophobicContact CB-CE2 4.12Å; H27-F31 WeakPolarHBondContact O-CD2 3.1Å; H27-F31 PolarHBondContact O-N 3.36Å; H27-L64 HydrophobicContact CB-CD2 4.42Å; H27-L64 WeakPolarHBondContact CD2-CD2 3.49Å; H27-E71 IonicContact CE1-OE2 3.45Å; H27-E71 PolarHBondContact CE1-OE2 3.21Å; H27-E71 IonicContact ND1-OE2 3.76Å
28I95.8Very high93Very high18 Ų1850.9 Ų50.99%0.09225%0.25CC..Hα-helixtrans-61.3-44.7179.1-68.5167.1000111V24 I25 W26 F31 D32 W136 L139V24-I28 HydrophobicContact CG1-CD1 4.1Å; V24-I28 HydrophobicContact CG1-CG1 4.48Å; V24-I28 WeakPolarHBondContact O-CG1 3.06Å; V24-I28 PolarHBondContact O-N 3.35Å; I25-I28 PolarHBondContact O-N 3.19Å; W26-I28 PolarHBondContact O-N 3.47Å; I28-F31 PolarHBondContact O-N 3.29Å; I28-D32 PolarHBondContact O-N 3.22Å; I28-W136 HydrophobicContact CD1-CD2 4.2Å; I28-W136 HydrophobicContact CD1-CE3 4.43Å; I28-W136 HydrophobicContact CG2-CZ2 4Å; I28-L139 HydrophobicContact CD1-CB 3.99Å; I28-L139 HydrophobicContact CD1-CD2 3.59Å; I28-L139 HydrophobicContact CD1-CG 4.34Å
29I95.8Very high92.1Very high101 Ų10156.3 Ų56.352%0.51827%0.267SS..Hα-helixtrans-62.1-46177.6-66166.7000110.4I25 W26 H27 F31 D32 E33I25-I29 HydrophobicContact CG2-CD1 3.92Å; I25-I29 WeakPolarHBondContact O-CG1 3.34Å; I25-I29 PolarHBondContact O-N 3.2Å; W26-I29 PolarHBondContact O-N 2.87Å; H27-I29 PolarHBondContact O-N 3.41Å; I29-F31 VanDerWaalsContact C-N 3.34Å; I29-F31 PolarHBondContact O-N 3.43Å; I29-D32 PolarHBondContact O-N 3.48Å; I29-D32 VanDerWaalsContact O-N 3.13Å; I29-E33 PolarHBondContact O-N 3.3Å
30A93.5Very high90.9Very high4 Ų457.8 Ų57.83%0.03327%0.273CS..Hα-helixtrans-60.8-40.8177.900000112.5W26 H27 D32 E33 L34 I60 L64W26-A30 HydrophobicContact CH2-CB 4.45Å; W26-A30 HydrophobicContact CZ3-CB 4.45Å; W26-A30 WeakPolarHBondContact O-CB 3.32Å; W26-A30 PolarHBondContact O-N 2.89Å; H27-A30 PolarHBondContact O-N 2.87Å; A30-D32 VanDerWaalsContact C-N 3.35Å; A30-E33 PolarHBondContact O-N 2.92Å; A30-L34 WeakPolarHBondContact O-CG 3.28Å; A30-L34 PolarHBondContact O-N 2.97Å; A30-I60 HydrophobicContact CB-CG2 3.81Å; A30-L64 HydrophobicContact CB-CD1 4.31Å; A30-L64 HydrophobicContact CB-CD2 3.79Å; A30-L64 HydrophobicContact CB-CG 4.2Å
31F92.7Very high89.3Confident0 Ų062.7 Ų62.70%030%0.304CS..Hα-helixtrans-68.3-32.6174.1-69.3-55.2000113H27 I28 I29 L34 R35 L64 Y117 I122 L128 C131 S135H27-F31 HydrophobicContact CB-CD2 4.47Å; H27-F31 HydrophobicContact CB-CE2 4.12Å; H27-F31 WeakPolarHBondContact O-CD2 3.1Å; H27-F31 PolarHBondContact O-N 3.36Å; I28-F31 PolarHBondContact O-N 3.29Å; I29-F31 VanDerWaalsContact C-N 3.34Å; I29-F31 PolarHBondContact O-N 3.43Å; F31-L34 HydrophobicContact CD1-CD1 4.18Å; F31-R35 WeakPolarHBondContact O-CB 3.29Å; F31-R35 PolarHBondContact O-N 3.21Å; F31-L64 HydrophobicContact CD1-CD1 4.46Å; F31-L64 HydrophobicContact CE1-CD1 3.91Å; F31-L64 HydrophobicContact CE2-CD2 4.34Å; F31-L64 HydrophobicContact CZ-CD1 4.22Å; F31-L64 HydrophobicContact CZ-CD2 4.07Å; F31-Y117 AromaticContact CE1-CD1 3.9Å; F31-Y117 HydrophobicContact CE1-CD1 3.9Å; F31-Y117 AromaticContact CE1-CE1 3.6Å; F31-Y117 HydrophobicContact CE1-CE1 3.6Å; F31-Y117 HydrophobicContact CZ-CD1 4Å; F31-Y117 AromaticContact CZ-CE1 3.28Å; F31-Y117 HydrophobicContact CZ-CE1 3.28Å; F31-Y117 AromaticContact CZ-CZ 3.73Å; F31-I122 HydrophobicContact CE1-CD1 4.11Å; F31-I122 HydrophobicContact CE1-CG1 4.47Å; F31-L128 HydrophobicContact CB-CD1 4.39Å; F31-L128 HydrophobicContact CD1-CD1 3.84Å; F31-C131 HydrophobicContact CD1-CB 4.23Å; F31-C131 HydrophobicContact CE1-CB 3.82Å; F31-C131 HydrophobicContact CE2-CB 4.41Å; F31-C131 HydrophobicContact CZ-CB 3.96Å; F31-S135 WeakPolarHBondContact CD2-OG 3.4Å; F31-S135 WeakPolarHBondContact CE2-OG 3.31Å
32D93.3Very high87.7Confident83 Ų8366.6 Ų66.644%0.44432%0.324SS..Hα-helixtrans-69.8-37.5175.6-163.660.7000112.2I28 I29 A30 R35 T36I28-D32 PolarHBondContact O-N 3.22Å; I29-D32 PolarHBondContact O-N 3.48Å; I29-D32 VanDerWaalsContact O-N 3.13Å; A30-D32 VanDerWaalsContact C-N 3.35Å; D32-R35 PolarHBondContact O-N 3.43Å; D32-T36 PolarHBondContact O-N 3.02Å; D32-T36 PolarHBondContact O-OG1 3.32Å
33E92.4Very high85.9Confident95 Ų9562.7 Ų62.744%0.44431%0.31SS..Hα-helixtrans-62.3-48.3171.9-170.3172.8-17700110.9I29 A30 R35 T36 D37 I60I29-E33 PolarHBondContact O-N 3.3Å; A30-E33 PolarHBondContact O-N 2.92Å; E33-R35 VanDerWaalsContact C-N 3.27Å; E33-R35 PolarHBondContact O-N 3.44Å; E33-T36 WeakPolarHBondContact O-CB 3.4Å; E33-T36 PolarHBondContact O-N 3.31Å; E33-T36 VanDerWaalsContact O-N 3.1Å; E33-D37 PolarHBondContact O-N 2.94Å; E33-I60 HydrophobicContact CB-CD1 4.33Å; E33-I60 VanDerWaalsContact CD-CD1 3.49Å; E33-I60 HydrophobicContact CG-CD1 3.86Å
34L89.7Confident84.3Confident11 Ų1168.2 Ų68.26%0.05834%0.337CS..Hα-helixtrans-58.5-38.3174.5-71.3174.5000112.4A30 F31 T36 D37 F38 I57 I60 L64 I122 L128A30-L34 WeakPolarHBondContact O-CG 3.28Å; A30-L34 PolarHBondContact O-N 2.97Å; F31-L34 HydrophobicContact CD1-CD1 4.18Å; L34-T36 VanDerWaalsContact C-N 3.35Å; L34-D37 PolarHBondContact O-N 2.9Å; L34-F38 PolarHBondContact O-N 3.21Å; L34-I57 HydrophobicContact CD2-CB 4.25Å; L34-I57 HydrophobicContact CD2-CG1 4.13Å; L34-I57 HydrophobicContact CD2-CG2 3.9Å; L34-I60 HydrophobicContact CD1-CG2 4.07Å; L34-I60 HydrophobicContact CD2-CB 4.38Å; L34-I60 HydrophobicContact CD2-CD1 4.34Å; L34-I60 HydrophobicContact CD2-CG2 4.25Å; L34-I60 HydrophobicContact CG-CG2 4.02Å; L34-L64 HydrophobicContact CD1-CD1 4.01Å; L34-I122 HydrophobicContact CD1-CG1 4.23Å; L34-L128 HydrophobicContact CB-CD1 4.12Å
35R89Confident83Confident83 Ų8372 Ų7231%0.31338%0.376SS..Hα-helixtrans-67.8-36.9177.1-173.8175.4-172.7162-0.1112.2F31 D32 E33 F38 K39 L128F31-R35 WeakPolarHBondContact O-CB 3.29Å; F31-R35 PolarHBondContact O-N 3.21Å; D32-R35 PolarHBondContact O-N 3.43Å; E33-R35 VanDerWaalsContact C-N 3.27Å; E33-R35 PolarHBondContact O-N 3.44Å; R35-F38 PolarHBondContact O-N 2.72Å; R35-K39 PolarHBondContact O-N 3.36Å; R35-L128 HydrophobicContact CB-CD2 3.86Å; R35-L128 HydrophobicContact CG-CD2 4.36Å
36T87.3Confident82.2Confident71 Ų7172.7 Ų72.744%0.43638%0.38SS..Hα-helixtrans-67.9-39.8175.8-60.80000110.8D32 E33 L34 K39 N40D32-T36 PolarHBondContact O-N 3.02Å; D32-T36 PolarHBondContact O-OG1 3.32Å; E33-T36 WeakPolarHBondContact O-CB 3.4Å; E33-T36 PolarHBondContact O-N 3.31Å; E33-T36 VanDerWaalsContact O-N 3.1Å; L34-T36 VanDerWaalsContact C-N 3.35Å; T36-K39 PolarHBondContact O-N 2.97Å; T36-N40 PolarHBondContact O-N 3.4Å; T36-N40 PolarHBondContact O-ND2 3.35Å
37D84.2Confident81.6Confident29 Ų2973.1 Ų73.116%0.15540%0.396CS..Hα-helixtrans-65.8-36.2173.6-86.9-30.3000112.8E33 L34 R53 I57E33-D37 PolarHBondContact O-N 2.94Å; L34-D37 PolarHBondContact O-N 2.9Å; D37-R53 IonicContact OD1-CZ 2.69Å; D37-R53 IonicContact OD1-NH1 3.45Å; D37-R53 PolarHBondContact OD1-NH1 2.88Å; D37-I57 HydrophobicContact CB-CD1 4.34Å; D37-I57 HydrophobicContact CB-CG1 4.42Å
38F80.1Confident81.2Confident103 Ų10376.2 Ų76.245%0.45242%0.421SS..Hα-helixtrans-63.8-39.5175.6-178.3-92.6000113.4L34 R35 M123 A125L34-F38 PolarHBondContact O-N 3.21Å; R35-F38 PolarHBondContact O-N 2.72Å; F38-M123 HydrophobicContact CD2-CG 4.01Å; F38-M123 WeakPolarHBondContact CD2-O 3.31Å; F38-M123 WeakPolarHBondContact CE2-O 3.47Å; F38-A125 HydrophobicContact CE1-CB 4Å; F38-A125 HydrophobicContact CE2-CB 4.47Å; F38-A125 HydrophobicContact CZ-CB 3.81Å
39K77.3Confident80.5Confident145 Ų14581.4 Ų81.463%0.6344%0.44SS*.Hα-helixtrans-74-26.8-178-74.6178.6-179.4175.70113.8R35 T36 P41R35-K39 PolarHBondContact O-N 3.36Å; T36-K39 PolarHBondContact O-N 2.97Å; K39-P41 VanDerWaalsContact O-CD 3.31Å; K39-P41 WeakPolarHBondContact O-CD 3.44Å
40N71.4Confident79.9Confident68 Ų6878 Ų7836%0.36443%0.427SS..SBendtrans-75.8114.9179.5-72-47.1000107.9T36 I42 R53T36-N40 PolarHBondContact O-N 3.4Å; T36-N40 PolarHBondContact O-ND2 3.35Å; N40-I42 PolarHBondContact O-N 3.29Å; N40-R53 PolarHBondContact ND2-NH1 3.18Å
41P62.4Low79.5Confident102 Ų10286.3 Ų86.366%0.66246%0.457SS*.  trans-52.9135.6169.424.2-31.9000107.3K39 D43K39-P41 VanDerWaalsContact O-CD 3.31Å; K39-P41 WeakPolarHBondContact O-CD 3.44Å; P41-D43 PolarHBondContact O-N 2.8Å
42I62.5Low79.2Confident108 Ų10892.2 Ų92.255%0.55449%0.485SS*.  trans-50.2115.7170.4-63.1174.3000104.7N40 Q44 A50N40-I42 PolarHBondContact O-N 3.29Å; I42-Q44 HydrophobicContact CB-CG 4.47Å; I42-Q44 HydrophobicContact CG2-CG 4.27Å; I42-Q44 PolarHBondContact O-N 3.48Å; I42-A50 HydrophobicContact CG2-CB 3.67Å
43D58.5Low78.7Confident68 Ų6890.3 Ų90.336%0.36447%0.472SS..  trans-61.982.8169.4-76.9-39.7000105.9P41 G45 N46 R49P41-D43 PolarHBondContact O-N 2.8Å; D43-G45 PolarHBondContact O-N 2.88Å; D43-N46 PolarHBondContact O-N 3.26Å; D43-R49 IonicContact OD2-CZ 3.87Å; D43-R49 IonicContact OD2-NE 2.73Å; D43-R49 IonicContact OD2-NH1 2.84Å; D43-R49 PolarHBondContact OD2-NH1 3.39Å
44Q62Low78.4Confident177 Ų17790.1 Ų90.183%0.82747%0.473SS*.THydrogen-bonded Turntrans-59.6-15.8-179.4-75.7179.9-9.600110.4I42 N46I42-Q44 HydrophobicContact CB-CG 4.47Å; I42-Q44 HydrophobicContact CG2-CG 4.27Å; I42-Q44 PolarHBondContact O-N 3.48Å; Q44-N46 VanDerWaalsContact C-N 3.28Å; Q44-N46 PolarHBondContact O-N 3.01Å
45G69.3Low78.3Confident81 Ų8195.3 Ų95.384%0.83550%0.495SS*.THydrogen-bonded Turntrans-64.6-20.8172.900000115.2D43D43-G45 PolarHBondContact O-N 2.88Å
46N79.9Confident78.4Confident83 Ų8393.2 Ų93.244%0.44449%0.491SS..  trans-136.4101.7175.6-168.6-19000112.7D43 Q44 A48 R49 A50D43-N46 PolarHBondContact O-N 3.26Å; Q44-N46 VanDerWaalsContact C-N 3.28Å; Q44-N46 PolarHBondContact O-N 3.01Å; N46-A48 PolarHBondContact O-N 3.41Å; N46-A48 VanDerWaalsContact O-N 3.16Å; N46-A48 WeakPolarHBondContact OD1-CB 2.87Å; N46-A48 PolarHBondContact OD1-N 3.39Å; N46-R49 HydrophobicContact CB-CB 4.21Å; N46-R49 PolarHBondContact O-N 3.2Å; N46-R49 VanDerWaalsContact O-N 3.09Å; N46-A50 PolarHBondContact O-N 2.93Å
47P82.5Confident78.4Confident104 Ų10490.9 Ų90.968%0.67548%0.475SS*.Hα-helixtrans-62.8-24.2-178.425.8-34.5000113.5R51P47-R51 PolarHBondContact O-N 3.5Å
48A84.9Confident78.6Confident66 Ų6694.2 Ų94.255%0.54549%0.49SS..Hα-helixtrans-67.9-41.3175.500000111.6N46 R51 E52N46-A48 PolarHBondContact O-N 3.41Å; N46-A48 VanDerWaalsContact O-N 3.16Å; N46-A48 WeakPolarHBondContact OD1-CB 2.87Å; N46-A48 PolarHBondContact OD1-N 3.39Å; A48-R51 PolarHBondContact O-N 2.97Å; A48-E52 PolarHBondContact O-N 3.38Å; A48-E52 VanDerWaalsContact O-N 3.09Å
49R82.6Confident79.1Confident127 Ų12796 Ų9648%0.47949%0.494SS..Hα-helixtrans-65.6-38.8177.3-166.3179.1-166.8177.910111.6D43 N46 E52 R53D43-R49 IonicContact OD2-CZ 3.87Å; D43-R49 IonicContact OD2-NE 2.73Å; D43-R49 IonicContact OD2-NH1 2.84Å; D43-R49 PolarHBondContact OD2-NH1 3.39Å; N46-R49 HydrophobicContact CB-CB 4.21Å; N46-R49 PolarHBondContact O-N 3.2Å; N46-R49 VanDerWaalsContact O-N 3.09Å; R49-E52 PolarHBondContact O-N 3.23Å; R49-R53 PolarHBondContact O-N 2.73Å; R49-R53 VanDerWaalsContact O-N 3.16Å
50A82.6Confident79.8Confident31 Ų3189.8 Ų89.826%0.25647%0.467SS..Hα-helixtrans-61.6-43.4175.100000112I42 N46 R53 L54I42-A50 HydrophobicContact CG2-CB 3.67Å; N46-A50 PolarHBondContact O-N 2.93Å; A50-R53 PolarHBondContact O-N 3Å; A50-L54 PolarHBondContact O-N 3Å; A50-L54 VanDerWaalsContact O-N 3.15Å
51R85.7Confident80.7Confident177 Ų17786.9 Ų86.967%0.66845%0.452SS*.Hα-helixtrans-66.1-38.1178-176.3-179.2-76.1-171.6-4.2112.6P47 A48 K55P47-R51 PolarHBondContact O-N 3.5Å; A48-R51 PolarHBondContact O-N 2.97Å; R51-K55 WeakPolarHBondContact O-CG 3.37Å; R51-K55 PolarHBondContact O-N 3.48Å; R51-K55 VanDerWaalsContact O-N 3.14Å
52E86.4Confident81.9Confident124 Ų12485 Ų8558%0.57944%0.44SS*.Hα-helixtrans-66.1-41.7177.9-172.6171.7-167.300112.1A48 R49 K55 N56A48-E52 PolarHBondContact O-N 3.38Å; A48-E52 VanDerWaalsContact O-N 3.09Å; R49-E52 PolarHBondContact O-N 3.23Å; E52-K55 PolarHBondContact O-N 2.92Å; E52-N56 PolarHBondContact O-N 3.09Å
53R82.7Confident83.3Confident43 Ų4383.8 Ų83.816%0.16243%0.434CS..Hα-helixtrans-60.4-46.7173.9-71.5-174.9-174.8-110.513.9112.2D37 N40 R49 A50 K55 N56 I57D37-R53 IonicContact OD1-CZ 2.69Å; D37-R53 IonicContact OD1-NH1 3.45Å; D37-R53 PolarHBondContact OD1-NH1 2.88Å; N40-R53 PolarHBondContact ND2-NH1 3.18Å; R49-R53 PolarHBondContact O-N 2.73Å; R49-R53 VanDerWaalsContact O-N 3.16Å; A50-R53 PolarHBondContact O-N 3Å; R53-K55 VanDerWaalsContact C-N 3.29Å; R53-K55 PolarHBondContact O-N 2.83Å; R53-N56 WeakPolarHBondContact O-CB 3.47Å; R53-N56 PolarHBondContact O-N 3.2Å; R53-I57 WeakPolarHBondContact O-CG1 3.4Å; R53-I57 PolarHBondContact O-N 3.16Å
54L85.5Confident84.8Confident92 Ų9280.5 Ų80.548%0.48242%0.417SS..Hα-helixtrans-56.9-44.8177-178.263.5000111.4A50 N56 I57 E58A50-L54 PolarHBondContact O-N 3Å; A50-L54 VanDerWaalsContact O-N 3.15Å; L54-N56 VanDerWaalsContact C-N 3.32Å; L54-N56 PolarHBondContact O-N 3.14Å; L54-I57 PolarHBondContact O-N 2.86Å; L54-E58 WeakPolarHBondContact O-CG 3.42Å; L54-E58 PolarHBondContact O-N 3.47Å
55K88.4Confident85.9Confident119 Ų11978 Ų7852%0.51740%0.4SS..Hα-helixtrans-62.7-36175.5-73.3179.4176.2-174.30113.1R51 E52 R53 R59R51-K55 WeakPolarHBondContact O-CG 3.37Å; R51-K55 PolarHBondContact O-N 3.48Å; R51-K55 VanDerWaalsContact O-N 3.14Å; E52-K55 PolarHBondContact O-N 2.92Å; R53-K55 VanDerWaalsContact C-N 3.29Å; R53-K55 PolarHBondContact O-N 2.83Å; K55-R59 WeakPolarHBondContact O-CB 3.36Å; K55-R59 PolarHBondContact O-N 3.33Å
56N89.3Confident86.8Confident40 Ų4082 Ų8221%0.21440%0.395CS..Hα-helixtrans-68.2-45.1176.2-72.4-14.3000111.1E52 R53 L54 E58 R59 I60E52-N56 PolarHBondContact O-N 3.09Å; R53-N56 WeakPolarHBondContact O-CB 3.47Å; R53-N56 PolarHBondContact O-N 3.2Å; L54-N56 VanDerWaalsContact C-N 3.32Å; L54-N56 PolarHBondContact O-N 3.14Å; N56-E58 PolarHBondContact O-N 3.17Å; N56-R59 WeakPolarHBondContact O-CB 3.4Å; N56-R59 PolarHBondContact O-N 2.9Å; N56-R59 PolarHBondContact OD1-NH1 3.1Å; N56-I60 VanDerWaalsContact O-CG1 3.32Å; N56-I60 WeakPolarHBondContact O-CG1 3.34Å; N56-I60 PolarHBondContact O-N 3.36Å
57I88.4Confident87.3Confident21 Ų2179.6 Ų79.611%0.10838%0.382CS..Hα-helixtrans-57.3-51.1174.9-66.7165.8000110.3L34 D37 R53 L54 R59 I60 C61 A119L34-I57 HydrophobicContact CD2-CB 4.25Å; L34-I57 HydrophobicContact CD2-CG1 4.13Å; L34-I57 HydrophobicContact CD2-CG2 3.9Å; D37-I57 HydrophobicContact CB-CD1 4.34Å; D37-I57 HydrophobicContact CB-CG1 4.42Å; R53-I57 WeakPolarHBondContact O-CG1 3.4Å; R53-I57 PolarHBondContact O-N 3.16Å; L54-I57 PolarHBondContact O-N 2.86Å; I57-R59 VanDerWaalsContact C-N 3.29Å; I57-R59 PolarHBondContact O-N 3.43Å; I57-I60 PolarHBondContact O-N 3.47Å; I57-C61 WeakPolarHBondContact O-CB 3.39Å; I57-C61 PolarHBondContact O-N 3.36Å; I57-C61 PolarHBondContact O-SG 2.92Å; I57-A119 HydrophobicContact CG2-CB 4.34Å
58E88.8Confident87.6Confident100 Ų10074.8 Ų74.847%0.46735%0.35SS..Hα-helixtrans-57.9-41.1177.2-73.9174.6177.400112.1L54 N56 C62 A119L54-E58 WeakPolarHBondContact O-CG 3.42Å; L54-E58 PolarHBondContact O-N 3.47Å; N56-E58 PolarHBondContact O-N 3.17Å; E58-C62 WeakPolarHBondContact O-CB 3.46Å; E58-C62 PolarHBondContact O-N 2.84Å; E58-A119 HydrophobicContact CG-CB 4.46Å
59R91Very high87.8Confident141 Ų14174.6 Ų74.653%0.53234%0.342SS..Hα-helixtrans-63.4-49177.2-171.9-169.5-59.7123.94.8111.3K55 N56 I57 C61 C62 L63K55-R59 WeakPolarHBondContact O-CB 3.36Å; K55-R59 PolarHBondContact O-N 3.33Å; N56-R59 WeakPolarHBondContact O-CB 3.4Å; N56-R59 PolarHBondContact O-N 2.9Å; N56-R59 PolarHBondContact OD1-NH1 3.1Å; I57-R59 VanDerWaalsContact C-N 3.29Å; I57-R59 PolarHBondContact O-N 3.43Å; R59-C61 VanDerWaalsContact C-N 3.33Å; R59-C61 PolarHBondContact O-N 2.81Å; R59-C62 PolarHBondContact O-N 3.5Å; R59-L63 HydrophobicContact CG-CD1 4.27Å; R59-L63 WeakPolarHBondContact O-CG 3.33Å; R59-L63 PolarHBondContact O-N 3.15Å
60I92Very high88.2Confident13 Ų1370.9 Ų70.97%0.06733%0.334CS..Hα-helixtrans-59.8-46.3179.3-66.7164.2000109.9A30 E33 L34 N56 I57 C62 L63 L64A30-I60 HydrophobicContact CB-CG2 3.81Å; E33-I60 HydrophobicContact CB-CD1 4.33Å; E33-I60 VanDerWaalsContact CD-CD1 3.49Å; E33-I60 HydrophobicContact CG-CD1 3.86Å; L34-I60 HydrophobicContact CD1-CG2 4.07Å; L34-I60 HydrophobicContact CD2-CB 4.38Å; L34-I60 HydrophobicContact CD2-CD1 4.34Å; L34-I60 HydrophobicContact CD2-CG2 4.25Å; L34-I60 HydrophobicContact CG-CG2 4.02Å; N56-I60 VanDerWaalsContact O-CG1 3.32Å; N56-I60 WeakPolarHBondContact O-CG1 3.34Å; N56-I60 PolarHBondContact O-N 3.36Å; I57-I60 PolarHBondContact O-N 3.47Å; I60-C62 VanDerWaalsContact C-N 3.35Å; I60-C62 PolarHBondContact O-N 3.44Å; I60-L63 PolarHBondContact O-N 2.83Å; I60-L63 VanDerWaalsContact O-N 3.16Å; I60-L64 HydrophobicContact CG2-CD1 3.75Å; I60-L64 HydrophobicContact CG2-CG 4.2Å; I60-L64 WeakPolarHBondContact O-CB 3.37Å; I60-L64 VanDerWaalsContact O-CG 3.31Å; I60-L64 WeakPolarHBondContact O-CG 3.08Å; I60-L64 PolarHBondContact O-N 2.9Å
61C88.7Confident88.8Confident7 Ų769.5 Ų69.55%0.04732%0.322CS..Hα-helixtrans-59.1-43.8177-65.10000112.2I57 R59 L63 L64 R65 Y117I57-C61 WeakPolarHBondContact O-CB 3.39Å; I57-C61 PolarHBondContact O-N 3.36Å; I57-C61 PolarHBondContact O-SG 2.92Å; R59-C61 VanDerWaalsContact C-N 3.33Å; R59-C61 PolarHBondContact O-N 2.81Å; C61-L63 VanDerWaalsContact C-N 3.34Å; C61-L63 PolarHBondContact O-N 3.25Å; C61-L64 PolarHBondContact O-N 3.38Å; C61-R65 WeakPolarHBondContact O-CB 3.23Å; C61-R65 PolarHBondContact O-N 2.85Å; C61-Y117 WeakPolarHBondContact CB-O 3.37Å
62C88.7Confident89.1Confident63 Ų6362 Ų6243%0.42629%0.294SS..Hα-helixtrans-63.2-39.2176.6-1720000112.3E58 R59 I60 R65 K66E58-C62 WeakPolarHBondContact O-CB 3.46Å; E58-C62 PolarHBondContact O-N 2.84Å; R59-C62 PolarHBondContact O-N 3.5Å; I60-C62 VanDerWaalsContact C-N 3.35Å; I60-C62 PolarHBondContact O-N 3.44Å; C62-R65 PolarHBondContact SG-NH2 3.23Å; C62-K66 PolarHBondContact O-N 3.03Å; C62-K66 VanDerWaalsContact O-N 3.16Å
63L91Very high89.4Confident82 Ų8259.4 Ų59.443%0.42929%0.29SS..Hα-helixtrans-69.1-45.5176.7-68.6173.5000111.8W26 R59 I60 C61 R65 K66 L67W26-L63 HydrophobicContact CH2-CB 3.44Å; W26-L63 VanDerWaalsContact CH2-CB 3.44Å; W26-L63 HydrophobicContact CZ2-CB 3.87Å; W26-L63 HydrophobicContact CZ2-CD1 4.12Å; R59-L63 HydrophobicContact CG-CD1 4.27Å; R59-L63 WeakPolarHBondContact O-CG 3.33Å; R59-L63 PolarHBondContact O-N 3.15Å; I60-L63 PolarHBondContact O-N 2.83Å; I60-L63 VanDerWaalsContact O-N 3.16Å; C61-L63 VanDerWaalsContact C-N 3.34Å; C61-L63 PolarHBondContact O-N 3.25Å; L63-R65 VanDerWaalsContact C-N 3.31Å; L63-R65 PolarHBondContact O-N 3.29Å; L63-K66 PolarHBondContact O-N 3.08Å; L63-K66 VanDerWaalsContact O-N 3.08Å; L63-L67 PolarHBondContact O-N 2.92Å
64L90.6Very high90Very high0 Ų058.9 Ų58.90%029%0.29CS..Hα-helixtrans-54.9-47.1174.4-73.9167000111.1W26 H27 A30 F31 L34 I60 C61 K66 L67 V68 Y117W26-L64 HydrophobicContact CE3-CD2 4.39Å; W26-L64 HydrophobicContact CH2-CD2 4.29Å; W26-L64 HydrophobicContact CH2-CG 4.27Å; W26-L64 HydrophobicContact CZ3-CD2 3.66Å; W26-L64 HydrophobicContact CZ3-CG 4.07Å; H27-L64 HydrophobicContact CB-CD2 4.42Å; H27-L64 WeakPolarHBondContact CD2-CD2 3.49Å; A30-L64 HydrophobicContact CB-CD1 4.31Å; A30-L64 HydrophobicContact CB-CD2 3.79Å; A30-L64 HydrophobicContact CB-CG 4.2Å; F31-L64 HydrophobicContact CD1-CD1 4.46Å; F31-L64 HydrophobicContact CE1-CD1 3.91Å; F31-L64 HydrophobicContact CE2-CD2 4.34Å; F31-L64 HydrophobicContact CZ-CD1 4.22Å; F31-L64 HydrophobicContact CZ-CD2 4.07Å; L34-L64 HydrophobicContact CD1-CD1 4.01Å; I60-L64 HydrophobicContact CG2-CD1 3.75Å; I60-L64 HydrophobicContact CG2-CG 4.2Å; I60-L64 WeakPolarHBondContact O-CB 3.37Å; I60-L64 VanDerWaalsContact O-CG 3.31Å; I60-L64 WeakPolarHBondContact O-CG 3.08Å; I60-L64 PolarHBondContact O-N 2.9Å; C61-L64 PolarHBondContact O-N 3.38Å; L64-K66 VanDerWaalsContact C-N 3.3Å; L64-K66 PolarHBondContact O-N 3.22Å; L64-L67 PolarHBondContact O-N 3.06Å; L64-L67 VanDerWaalsContact O-N 3.15Å; L64-V68 PolarHBondContact O-N 3.39Å; L64-Y117 HydrophobicContact CB-CD2 3.88Å; L64-Y117 HydrophobicContact CB-CE2 4.29Å; L64-Y117 HydrophobicContact CB-CG 4.18Å
65R85.3Confident90.5Very high123 Ų12354.5 Ų54.546%0.46427%0.267SS..Hα-helixtrans-59-39.3176179.9179.965.4-180-1.6112.8C61 C62 L63 L67 V68 V115C61-R65 WeakPolarHBondContact O-CB 3.23Å; C61-R65 PolarHBondContact O-N 2.85Å; C62-R65 PolarHBondContact SG-NH2 3.23Å; L63-R65 VanDerWaalsContact C-N 3.31Å; L63-R65 PolarHBondContact O-N 3.29Å; R65-L67 VanDerWaalsContact C-N 3.32Å; R65-V68 WeakPolarHBondContact O-CG1 3.43Å; R65-V115 HydrophobicContact CG-CG1 4.29Å
66K88.6Confident90.8Very high167 Ų16750.1 Ų50.173%0.72626%0.256SS*.Hα-helixtrans-72.3-28.4179.7-168175.3-179.8-179.30112C62 L63 L64 P70C62-K66 PolarHBondContact O-N 3.03Å; C62-K66 VanDerWaalsContact O-N 3.16Å; L63-K66 PolarHBondContact O-N 3.08Å; L63-K66 VanDerWaalsContact O-N 3.08Å; L64-K66 VanDerWaalsContact C-N 3.3Å; L64-K66 PolarHBondContact O-N 3.22Å; K66-P70 WeakPolarHBondContact O-CD 3.1Å; K66-P70 WeakPolarHBondContact O-CG 3.15Å
67L90.5Very high91.1Very high32 Ų3253 Ų5317%0.16827%0.27CS..Hα-helixtrans-90.4-28.4-173.9-160.767.1000114.2F23 W26 L63 L64 R65 V69 P70 E71F23-L67 HydrophobicContact CB-CD2 4.25Å; F23-L67 HydrophobicContact CD1-CD1 4.01Å; F23-L67 HydrophobicContact CD1-CD2 4.27Å; F23-L67 HydrophobicContact CD1-CG 4.48Å; F23-L67 HydrophobicContact CD2-CD1 4.34Å; F23-L67 HydrophobicContact CE1-CD1 4.01Å; F23-L67 HydrophobicContact CE2-CD1 4.34Å; F23-L67 HydrophobicContact CG-CD1 4.19Å; F23-L67 HydrophobicContact CG-CD2 4.32Å; F23-L67 HydrophobicContact CG-CG 4.33Å; F23-L67 HydrophobicContact CZ-CD1 4.18Å; W26-L67 HydrophobicContact CD2-CD2 3.91Å; W26-L67 HydrophobicContact CE3-CD2 3.22Å; W26-L67 HydrophobicContact CG-CD2 4.48Å; W26-L67 HydrophobicContact CZ3-CB 4.33Å; W26-L67 HydrophobicContact CZ3-CD2 3.68Å; L63-L67 PolarHBondContact O-N 2.92Å; L64-L67 PolarHBondContact O-N 3.06Å; L64-L67 VanDerWaalsContact O-N 3.15Å; R65-L67 VanDerWaalsContact C-N 3.32Å; L67-V69 VanDerWaalsContact C-N 3.31Å; L67-V69 PolarHBondContact O-N 2.97Å; L67-P70 VanDerWaalsContact O-CD 3.25Å; L67-P70 WeakPolarHBondContact O-CD 3.47Å; L67-E71 PolarHBondContact O-N 3.16Å; L67-E71 VanDerWaalsContact O-N 3.17Å
68V89Confident91.4Very high2 Ų252 Ų521%0.01227%0.265CS..Hα-helixtrans-63.2-33.5-179.871.90000113.3L64 R65 E71 Y72 M116 Y117L64-V68 PolarHBondContact O-N 3.39Å; R65-V68 WeakPolarHBondContact O-CG1 3.43Å; V68-E71 PolarHBondContact O-N 2.63Å; V68-Y72 HydrophobicContact CG2-CE1 3.82Å; V68-Y72 HydrophobicContact CG2-CE2 3.91Å; V68-Y72 VanDerWaalsContact CG2-CZ 3.45Å; V68-Y72 WeakPolarHBondContact CG2-OH 3.43Å; V68-Y72 PolarHBondContact O-N 3.4Å; V68-M116 HydrophobicContact CG1-SD 4.02Å; V68-M116 HydrophobicContact CG2-SD 4.24Å; V68-Y117 HydrophobicContact CB-CE2 4.35Å; V68-Y117 HydrophobicContact CG1-CE2 4.49Å
69V88.6Confident91.7Very high63 Ų6347.3 Ų47.338%0.38224%0.244SC..Hα-helixtrans-69.3-48.8178.6172.20000111.7L67 E71 Y72 S73L67-V69 VanDerWaalsContact C-N 3.31Å; L67-V69 PolarHBondContact O-N 2.97Å; V69-E71 VanDerWaalsContact C-N 3.3Å; V69-E71 PolarHBondContact O-N 2.94Å; V69-Y72 PolarHBondContact O-N 3.44Å; V69-S73 WeakPolarHBondContact O-CB 3.3Å; V69-S73 PolarHBondContact O-N 3.43Å; V69-S73 PolarHBondContact O-OG 3.36Å
70P91.4Very high91.9Very high48 Ų4845.4 Ų45.431%0.31224%0.244SC..Hα-helixtrans-53.1-42169.2-29.933.1000114.2F23 K66 L67 Y72 S73 I74F23-P70 HydrophobicContact CE2-CB 4.4Å; K66-P70 WeakPolarHBondContact O-CD 3.1Å; K66-P70 WeakPolarHBondContact O-CG 3.15Å; L67-P70 VanDerWaalsContact O-CD 3.25Å; L67-P70 WeakPolarHBondContact O-CD 3.47Å; P70-Y72 PolarHBondContact O-N 2.91Å; P70-S73 PolarHBondContact O-N 3.4Å; P70-I74 WeakPolarHBondContact O-CG1 3.28Å; P70-I74 PolarHBondContact O-N 3.4Å
71E93.3Very high92Very high2 Ų245.9 Ų45.91%0.00925%0.246CC..Hα-helixtrans-56.7-52.3178.1-171.6-164.3150.200111.4L20 H27 L67 V68 V69 S73 I74 H75 H101 K138L20-E71 HydrophobicContact CD2-CB 4.28Å; L20-E71 HydrophobicContact CD2-CG 3.68Å; H27-E71 IonicContact CE1-OE2 3.45Å; H27-E71 PolarHBondContact CE1-OE2 3.21Å; H27-E71 IonicContact ND1-OE2 3.76Å; L67-E71 PolarHBondContact O-N 3.16Å; L67-E71 VanDerWaalsContact O-N 3.17Å; V68-E71 PolarHBondContact O-N 2.63Å; V69-E71 VanDerWaalsContact C-N 3.3Å; V69-E71 PolarHBondContact O-N 2.94Å; E71-S73 VanDerWaalsContact C-N 3.28Å; E71-S73 PolarHBondContact O-N 3.49Å; E71-I74 PolarHBondContact O-N 3.34Å; E71-H75 WeakPolarHBondContact O-CB 3.5Å; E71-H75 PolarHBondContact O-N 3.49Å; E71-H101 IonicContact OE1-NE2 3.82Å; E71-K138 WeakPolarHBondContact OE1-CD 3.37Å; E71-K138 IonicContact OE1-NZ 3.94Å
72Y93Very high92.2Very high19 Ų1945.6 Ų45.68%0.07524%0.244CC..Hα-helixtrans-65.6-34.6179.5-60.6-9.8000112.1V68 V69 P70 H75 G76 H101 R104 Y105 M116V68-Y72 HydrophobicContact CG2-CE1 3.82Å; V68-Y72 HydrophobicContact CG2-CE2 3.91Å; V68-Y72 VanDerWaalsContact CG2-CZ 3.45Å; V68-Y72 WeakPolarHBondContact CG2-OH 3.43Å; V68-Y72 PolarHBondContact O-N 3.4Å; V69-Y72 PolarHBondContact O-N 3.44Å; P70-Y72 PolarHBondContact O-N 2.91Å; Y72-H75 PolarHBondContact O-N 3.24Å; Y72-G76 PolarHBondContact O-N 3.34Å; Y72-H101 HydrophobicContact CD1-CB 4.01Å; Y72-H101 AromaticContact CD1-CD2 3.4Å; Y72-H101 VanDerWaalsContact CD1-CD2 3.4Å; Y72-H101 WeakPolarHBondContact CD1-CD2 3.5Å; Y72-H101 AromaticContact CD1-CE1 3.99Å; Y72-H101 AromaticContact CD1-CG 3.53Å; Y72-H101 AromaticContact CD1-ND1 3.9Å; Y72-H101 AromaticContact CD1-NE2 3.73Å; Y72-H101 HydrophobicContact CD2-CB 4.49Å; Y72-H101 HydrophobicContact CE1-CB 4.36Å; Y72-H101 AromaticContact CE1-CD2 3.2Å; Y72-H101 WeakPolarHBondContact CE1-CD2 3.43Å; Y72-H101 AromaticContact CE1-CG 3.8Å; Y72-H101 AromaticContact CE1-NE2 3.61Å; Y72-H101 HydrophobicContact CG-CB 4.1Å; Y72-H101 AromaticContact CZ-CD2 3.98Å; Y72-R104 WeakPolarHBondContact OH-CG 3.38Å; Y72-Y105 HydrophobicContact CD2-CD2 4.45Å; Y72-M116 HydrophobicContact CE2-CE 4.22Å
73S92.9Very high92.5Very high71 Ų7146.6 Ų46.650%0.49725%0.245SC..Hα-helixtrans-66-45.2179-56.20000111.4V69 P70 E71 G76 L77V69-S73 WeakPolarHBondContact O-CB 3.3Å; V69-S73 PolarHBondContact O-N 3.43Å; V69-S73 PolarHBondContact O-OG 3.36Å; P70-S73 PolarHBondContact O-N 3.4Å; E71-S73 VanDerWaalsContact C-N 3.28Å; E71-S73 PolarHBondContact O-N 3.49Å; S73-G76 PolarHBondContact O-N 3.5Å; S73-L77 VanDerWaalsContact O-CB 3.31Å; S73-L77 WeakPolarHBondContact O-CB 3.23Å; S73-L77 PolarHBondContact O-N 3.36Å
74I95.6Very high92.6Very high32 Ų3246.9 Ų46.916%0.16425%0.252CS..Hα-helixtrans-66.8-42.5177.2-64.4166.5000110.2L16 L20 F23 P70 E71 L77 F78L16-I74 HydrophobicContact CB-CG2 3.84Å; L16-I74 HydrophobicContact CD1-CG2 4.44Å; L16-I74 HydrophobicContact CD2-CG2 4.06Å; L16-I74 HydrophobicContact CG-CG2 4.32Å; L20-I74 HydrophobicContact CD1-CB 4.44Å; L20-I74 HydrophobicContact CD1-CG2 3.84Å; L20-I74 HydrophobicContact CD2-CB 4.01Å; L20-I74 HydrophobicContact CD2-CD1 4.45Å; L20-I74 HydrophobicContact CD2-CG2 4.1Å; L20-I74 HydrophobicContact CG-CB 4.29Å; L20-I74 HydrophobicContact CG-CG2 3.81Å; F23-I74 HydrophobicContact CD2-CD1 4.33Å; F23-I74 HydrophobicContact CE2-CD1 3.71Å; P70-I74 WeakPolarHBondContact O-CG1 3.28Å; P70-I74 PolarHBondContact O-N 3.4Å; E71-I74 PolarHBondContact O-N 3.34Å; I74-L77 PolarHBondContact O-N 2.9Å; I74-F78 WeakPolarHBondContact O-CD1 3.46Å; I74-F78 PolarHBondContact O-N 3.38Å
75H96.3Very high92.7Very high0 Ų047.8 Ų47.80%026%0.26CS..Hα-helixtrans-59-48176.2-171.4-105000112.2E71 Y72 L77 F78 C79 N94 H101 Y142E71-H75 WeakPolarHBondContact O-CB 3.5Å; E71-H75 PolarHBondContact O-N 3.49Å; Y72-H75 PolarHBondContact O-N 3.24Å; H75-L77 PolarHBondContact O-N 2.81Å; H75-F78 VanDerWaalsContact CA-CE1 3.49Å; H75-F78 HydrophobicContact CB-CE1 4.27Å; H75-F78 AromaticContact CD2-CE1 3.55Å; H75-F78 AromaticContact CD2-CE2 3.97Å; H75-F78 AromaticContact CD2-CZ 3.1Å; H75-F78 WeakPolarHBondContact CD2-CZ 3.18Å; H75-F78 AromaticContact NE2-CZ 3.53Å; H75-C79 PolarHBondContact O-N 3.42Å; H75-C79 PolarHBondContact O-SG 3.17Å; H75-N94 PolarHBondContact NE2-OD1 3.49Å; H75-N94 VanDerWaalsContact NE2-OD1 3.17Å; H75-H101 AromaticContact CE1-ND1 3.98Å; H75-H101 AromaticContact CG-CE1 3.73Å; H75-H101 AromaticContact CG-ND1 3.51Å; H75-H101 AromaticContact ND1-CE1 3.73Å; H75-H101 AromaticContact ND1-ND1 3.14Å; H75-H101 PolarHBondContact ND1-ND1 3.46Å; H75-H101 VanDerWaalsContact ND1-ND1 3.14Å; H75-Y142 AromaticContact CD2-CE1 3.71Å
76G94.8Very high93Very high26 Ų2644.7 Ų44.727%0.26826%0.26SS..Hα-helixtrans-63.9-38.8176.600000113.1Y72 S73 C79 L80Y72-G76 PolarHBondContact O-N 3.34Å; S73-G76 PolarHBondContact O-N 3.5Å; G76-C79 PolarHBondContact O-N 2.76Å; G76-L80 WeakPolarHBondContact O-CB 3.08Å; G76-L80 PolarHBondContact O-N 3.47Å
77L95.3Very high93.1Very high100 Ų10039 Ų3952%0.52424%0.236SC..Hα-helixtrans-60.2-49.9-179.8-179.169.7000111.9L16 S73 I74 H75 C79 L80 M81L16-L77 HydrophobicContact CD1-CD2 4.29Å; S73-L77 VanDerWaalsContact O-CB 3.31Å; S73-L77 WeakPolarHBondContact O-CB 3.23Å; S73-L77 PolarHBondContact O-N 3.36Å; I74-L77 PolarHBondContact O-N 2.9Å; H75-L77 PolarHBondContact O-N 2.81Å; L77-C79 VanDerWaalsContact C-N 3.35Å; L77-L80 WeakPolarHBondContact O-CB 3.23Å; L77-L80 PolarHBondContact O-N 2.89Å; L77-M81 PolarHBondContact O-N 3.23Å
78F94.1Very high93.2Very high0 Ų045.7 Ų45.70%026%0.259CS..Hα-helixtrans-73.8-28.9-179.274.2-115.4000112.1T13 L16 L20 I74 H75 L80 M81 F82 N94T13-F78 HydrophobicContact CG2-CB 4.28Å; T13-F78 HydrophobicContact CG2-CD2 4.09Å; T13-F78 HydrophobicContact CG2-CG 4.11Å; L16-F78 HydrophobicContact CD1-CB 4.25Å; L20-F78 HydrophobicContact CD1-CD1 4.33Å; L20-F78 HydrophobicContact CD1-CE1 3.59Å; I74-F78 WeakPolarHBondContact O-CD1 3.46Å; I74-F78 PolarHBondContact O-N 3.38Å; H75-F78 VanDerWaalsContact CA-CE1 3.49Å; H75-F78 HydrophobicContact CB-CE1 4.27Å; H75-F78 AromaticContact CD2-CE1 3.55Å; H75-F78 AromaticContact CD2-CE2 3.97Å; H75-F78 AromaticContact CD2-CZ 3.1Å; H75-F78 WeakPolarHBondContact CD2-CZ 3.18Å; H75-F78 AromaticContact NE2-CZ 3.53Å; F78-L80 VanDerWaalsContact C-N 3.34Å; F78-M81 HydrophobicContact CB-CE 4.22Å; F78-M81 WeakPolarHBondContact O-CB 3.43Å; F78-M81 PolarHBondContact O-N 3.48Å; F78-F82 AromaticContact CD2-CD2 3.94Å; F78-F82 HydrophobicContact CD2-CD2 3.94Å; F78-F82 AromaticContact CD2-CE2 3.79Å; F78-F82 HydrophobicContact CD2-CE2 3.79Å; F78-F82 HydrophobicContact CE2-CE2 4.32Å; F78-F82 VanDerWaalsContact O-CD2 3.29Å; F78-F82 WeakPolarHBondContact O-CD2 3.46Å; F78-F82 PolarHBondContact O-N 2.89Å; F78-N94 WeakPolarHBondContact CE2-OD1 3.24Å
79C95Very high93.4Very high3 Ų350.4 Ų50.42%0.0229%0.288CS..Hα-helixtrans-63.1-42.1172.1-70.60000111.2H75 G76 L77 M81 F82 L83 L91 L98H75-C79 PolarHBondContact O-N 3.42Å; H75-C79 PolarHBondContact O-SG 3.17Å; G76-C79 PolarHBondContact O-N 2.76Å; L77-C79 VanDerWaalsContact C-N 3.35Å; C79-M81 VanDerWaalsContact C-N 3.29Å; C79-M81 PolarHBondContact O-N 3.47Å; C79-F82 PolarHBondContact O-N 3.07Å; C79-L83 PolarHBondContact O-N 3.19Å; C79-L91 HydrophobicContact CB-CD1 4.3Å; C79-L98 HydrophobicContact CB-CD1 4.42Å; C79-L98 HydrophobicContact CB-CD2 4Å
80L94.9Very high93.6Very high101 Ų10147.4 Ų47.453%0.52927%0.27SS..Hα-helixtrans-61.7-40.9173.6-179.664000111.2G76 L77 F78 F82 L83 C84G76-L80 WeakPolarHBondContact O-CB 3.08Å; G76-L80 PolarHBondContact O-N 3.47Å; L77-L80 WeakPolarHBondContact O-CB 3.23Å; L77-L80 PolarHBondContact O-N 2.89Å; F78-L80 VanDerWaalsContact C-N 3.34Å; L80-F82 PolarHBondContact O-N 3.48Å; L80-L83 HydrophobicContact CD1-CD2 4.4Å; L80-L83 WeakPolarHBondContact O-CB 3.31Å; L80-L83 PolarHBondContact O-N 3.5Å; L80-C84 PolarHBondContact O-N 3.46Å; L80-C84 PolarHBondContact O-SG 3.17Å; L80-C84 VanDerWaalsContact O-SG 3.38Å
81M93.8Very high93.7Very high23 Ų2346 Ų4611%0.11326%0.26CS..Hα-helixtrans-63.3-40.3176.9-173.3176.761.200112.4C9 L12 T13 L77 F78 C79 C84 A85C9-M81 HydrophobicContact CB-CE 3.87Å; C9-M81 HydrophobicContact CB-CG 3.81Å; C9-M81 HydrophobicContact CB-SD 3.93Å; C9-M81 WeakPolarHBondContact O-CE 3.46Å; C9-M81 WeakPolarHBondContact SG-CG 3.44Å; L12-M81 HydrophobicContact CB-CE 4.11Å; L12-M81 HydrophobicContact CB-SD 4.31Å; L12-M81 HydrophobicContact CD2-CE 4.27Å; L12-M81 HydrophobicContact CD2-SD 3.75Å; L12-M81 HydrophobicContact CG-CE 4.38Å; L12-M81 HydrophobicContact CG-SD 4.44Å; T13-M81 WeakPolarHBondContact OG1-CE 3.38Å; L77-M81 PolarHBondContact O-N 3.23Å; F78-M81 HydrophobicContact CB-CE 4.22Å; F78-M81 WeakPolarHBondContact O-CB 3.43Å; F78-M81 PolarHBondContact O-N 3.48Å; C79-M81 VanDerWaalsContact C-N 3.29Å; C79-M81 PolarHBondContact O-N 3.47Å; M81-C84 PolarHBondContact O-N 3.07Å; M81-A85 WeakPolarHBondContact O-CB 3.25Å; M81-A85 PolarHBondContact O-N 3.3Å
82F94.6Very high93.8Very high0 Ų047.6 Ų47.60%028%0.277CS..Hα-helixtrans-67.8-34.6173.4-73.4-49.5000113.4C9 Y10 T13 F78 C79 L80 A85 A86 E87 T90 Y149C9-F82 HydrophobicContact CB-CD1 4.49Å; C9-F82 HydrophobicContact CB-CE1 4.44Å; Y10-F82 AromaticContact CD1-CE1 3.7Å; Y10-F82 HydrophobicContact CD1-CE1 3.7Å; Y10-F82 AromaticContact CD1-CZ 3.93Å; Y10-F82 HydrophobicContact CD1-CZ 3.93Å; Y10-F82 AromaticContact CE1-CE1 3.57Å; Y10-F82 HydrophobicContact CE1-CE1 3.57Å; Y10-F82 AromaticContact CE1-CZ 3.92Å; Y10-F82 HydrophobicContact CE1-CZ 3.92Å; Y10-F82 HydrophobicContact CG-CE1 4.28Å; T13-F82 HydrophobicContact CG2-CE2 3.72Å; T13-F82 HydrophobicContact CG2-CZ 3.68Å; T13-F82 WeakPolarHBondContact OG1-CZ 3.1Å; F78-F82 AromaticContact CD2-CD2 3.94Å; F78-F82 HydrophobicContact CD2-CD2 3.94Å; F78-F82 AromaticContact CD2-CE2 3.79Å; F78-F82 HydrophobicContact CD2-CE2 3.79Å; F78-F82 HydrophobicContact CE2-CE2 4.32Å; F78-F82 VanDerWaalsContact O-CD2 3.29Å; F78-F82 WeakPolarHBondContact O-CD2 3.46Å; F78-F82 PolarHBondContact O-N 2.89Å; C79-F82 PolarHBondContact O-N 3.07Å; L80-F82 PolarHBondContact O-N 3.48Å; F82-A85 CarbonylContact O-C 3.59Å; F82-A85 PolarHBondContact O-N 3.18Å; F82-A86 PolarHBondContact O-N 3.32Å; F82-A86 VanDerWaalsContact O-N 3.12Å; F82-E87 HydrophobicContact CD1-CB 4.13Å; F82-E87 HydrophobicContact CD1-CG 4.47Å; F82-E87 PolarHBondContact O-N 3.28Å; F82-T90 WeakPolarHBondContact CD1-OG1 3.38Å; F82-T90 WeakPolarHBondContact CG-OG1 3.47Å; F82-Y149 HydrophobicContact CE2-CE1 4.18Å; F82-Y149 HydrophobicContact CZ-CD1 4.29Å; F82-Y149 HydrophobicContact CZ-CE1 4.31Å
83L94.4Very high93.8Very high85 Ų8550.7 Ų50.745%0.44529%0.294SS..Hα-helixtrans-61.1-45.2171.7-178.368000110.9C79 L80 A85 A86 W88 L91C79-L83 PolarHBondContact O-N 3.19Å; L80-L83 HydrophobicContact CD1-CD2 4.4Å; L80-L83 WeakPolarHBondContact O-CB 3.31Å; L80-L83 PolarHBondContact O-N 3.5Å; L83-A85 VanDerWaalsContact C-N 3.29Å; L83-A85 PolarHBondContact O-N 3.42Å; L83-A86 PolarHBondContact O-N 3.33Å; L83-W88 HydrophobicContact CD1-CH2 4.18Å; L83-W88 HydrophobicContact CD1-CZ3 4.05Å; L83-L91 HydrophobicContact CB-CD2 4.22Å; L83-L91 HydrophobicContact CD1-CD2 3.67Å
84C93.4Very high93.9Very high87 Ų8747.3 Ų47.359%0.58827%0.27SS*.Hα-helixtrans-65-31.3175.2-66.70000113F5 L80 M81 A86F5-C84 HydrophobicContact CE1-CB 3.98Å; F5-C84 HydrophobicContact CZ-CB 4.23Å; L80-C84 PolarHBondContact O-N 3.46Å; L80-C84 PolarHBondContact O-SG 3.17Å; L80-C84 VanDerWaalsContact O-SG 3.38Å; M81-C84 PolarHBondContact O-N 3.07Å; C84-A86 VanDerWaalsContact C-N 3.28Å
85A91.8Very high93.8Very high19 Ų1950.1 Ų50.116%0.15729%0.285CS..THydrogen-bonded Turntrans-82.3-2.3177.800000113.9F5 C9 M81 F82 L83 E87F5-A85 HydrophobicContact CD1-CB 3.92Å; F5-A85 HydrophobicContact CE1-CB 3.89Å; C9-A85 HydrophobicContact CB-CB 4.38Å; M81-A85 WeakPolarHBondContact O-CB 3.25Å; M81-A85 PolarHBondContact O-N 3.3Å; F82-A85 CarbonylContact O-C 3.59Å; F82-A85 PolarHBondContact O-N 3.18Å; L83-A85 VanDerWaalsContact C-N 3.29Å; L83-A85 PolarHBondContact O-N 3.42Å; A85-E87 HydrophobicContact CB-CG 4.12Å; A85-E87 PolarHBondContact O-N 2.93Å
86A91.1Very high93.7Very high58 Ų5854.2 Ų54.248%0.47931%0.312SS..THydrogen-bonded Turntrans56.429.5-175.800000114.4F82 L83 C84 W88F82-A86 PolarHBondContact O-N 3.32Å; F82-A86 VanDerWaalsContact O-N 3.12Å; L83-A86 PolarHBondContact O-N 3.33Å; C84-A86 VanDerWaalsContact C-N 3.28Å; A86-W88 VanDerWaalsContact C-N 3.32Å; A86-W88 PolarHBondContact O-N 3.27Å
87E92.2Very high93.6Very high47 Ų4753.8 Ų53.822%0.2230%0.303CS..  trans-8572.2178-73.3-71.315700110.4A6 Y10 F82 A85 V89 T90 L91A6-E87 HydrophobicContact CB-CG 4.42Å; Y10-E87 HydrophobicContact CE2-CG 4.09Å; Y10-E87 VanDerWaalsContact OH-CD 3.3Å; Y10-E87 PolarHBondContact OH-OE2 3.05Å; F82-E87 HydrophobicContact CD1-CB 4.13Å; F82-E87 HydrophobicContact CD1-CG 4.47Å; F82-E87 PolarHBondContact O-N 3.28Å; A85-E87 HydrophobicContact CB-CG 4.12Å; A85-E87 PolarHBondContact O-N 2.93Å; E87-V89 VanDerWaalsContact C-N 3.29Å; E87-V89 PolarHBondContact O-N 3.16Å; E87-T90 HydrophobicContact CB-CG2 4.27Å; E87-T90 WeakPolarHBondContact CB-OG1 3.01Å; E87-T90 PolarHBondContact O-N 3.34Å; E87-T90 PolarHBondContact O-OG1 3.4Å; E87-L91 PolarHBondContact O-N 3.08Å
88W91.4Very high93.5Very high173 Ų17350.9 Ų50.966%0.65529%0.288SS*.Hα-helixtrans-60.6-33.9-170.9-62.1107.2000114.4L83 A86 L91 G92L83-W88 HydrophobicContact CD1-CH2 4.18Å; L83-W88 HydrophobicContact CD1-CZ3 4.05Å; A86-W88 VanDerWaalsContact C-N 3.32Å; A86-W88 PolarHBondContact O-N 3.27Å; W88-L91 HydrophobicContact CE3-CD2 4.23Å; W88-L91 HydrophobicContact CZ3-CD2 4.22Å; W88-G92 PolarHBondContact O-N 3.15Å
89V92.9Very high93.5Very high101 Ų10157.5 Ų57.561%0.61232%0.317SS*.Hα-helixtrans-66.6-43.1179.1-177.70000110.3E87 G92 L93 Y148E87-V89 VanDerWaalsContact C-N 3.29Å; E87-V89 PolarHBondContact O-N 3.16Å; V89-G92 PolarHBondContact O-N 3Å; V89-L93 WeakPolarHBondContact O-CG 3.25Å; V89-L93 PolarHBondContact O-N 2.86Å; V89-Y148 WeakPolarHBondContact CG1-OH 3.44Å
90T93.9Very high93.4Very high0 Ų060 Ų600%033%0.326CS..Hα-helixtrans-74.9-37-176.870.60000111.9Y10 F82 E87 G92 L93 N94 Y148Y10-T90 HydrophobicContact CE1-CG2 3.83Å; Y10-T90 WeakPolarHBondContact OH-CG2 3.39Å; F82-T90 WeakPolarHBondContact CD1-OG1 3.38Å; F82-T90 WeakPolarHBondContact CG-OG1 3.47Å; E87-T90 HydrophobicContact CB-CG2 4.27Å; E87-T90 WeakPolarHBondContact CB-OG1 3.01Å; E87-T90 PolarHBondContact O-N 3.34Å; E87-T90 PolarHBondContact O-OG1 3.4Å; T90-G92 VanDerWaalsContact C-N 3.34Å; T90-L93 PolarHBondContact O-N 3.43Å; T90-N94 PolarHBondContact O-N 3.05Å; T90-N94 PolarHBondContact O-ND2 2.73Å; T90-Y148 HydrophobicContact CG2-CE1 3.47Å; T90-Y148 VanDerWaalsContact CG2-CE1 3.47Å; T90-Y148 WeakPolarHBondContact CG2-OH 3.22Å
91L94Very high93.2Very high19 Ų1955.4 Ų55.410%0.09930%0.302CS..Hα-helixtrans-61.9-46.7169.9-174.465.2000109.8C79 L83 E87 W88 L93 N94 I95C79-L91 HydrophobicContact CB-CD1 4.3Å; L83-L91 HydrophobicContact CB-CD2 4.22Å; L83-L91 HydrophobicContact CD1-CD2 3.67Å; E87-L91 PolarHBondContact O-N 3.08Å; W88-L91 HydrophobicContact CE3-CD2 4.23Å; W88-L91 HydrophobicContact CZ3-CD2 4.22Å; L91-L93 VanDerWaalsContact C-N 3.29Å; L91-L93 PolarHBondContact O-N 2.89Å; L91-N94 CarbonylContact O-C 3.58Å; L91-N94 WeakPolarHBondContact O-CA 3.18Å; L91-N94 PolarHBondContact O-N 3.45Å; L91-I95 HydrophobicContact CG-CD1 4.43Å; L91-I95 HydrophobicContact CG-CG1 4.41Å; L91-I95 WeakPolarHBondContact O-CG1 3.34Å; L91-I95 PolarHBondContact O-N 2.8Å
92G93.6Very high93.1Very high36 Ų3658.2 Ų58.237%0.37132%0.317SS..Hα-helixtrans-53.2-42.9176.300000113.5W88 V89 T90 N94 P96W88-G92 PolarHBondContact O-N 3.15Å; V89-G92 PolarHBondContact O-N 3Å; T90-G92 VanDerWaalsContact C-N 3.34Å; G92-N94 VanDerWaalsContact C-N 3.33Å; G92-N94 PolarHBondContact O-N 2.97Å; G92-P96 WeakPolarHBondContact O-CD 3.44Å
93L93.9Very high92.9Very high83 Ų8363.1 Ų63.144%0.43534%0.336SS..Hα-helixtrans-67.1-31.1175.6-69.1173.7000113.1V89 T90 L91 P96 F141 Y148V89-L93 WeakPolarHBondContact O-CG 3.25Å; V89-L93 PolarHBondContact O-N 2.86Å; T90-L93 PolarHBondContact O-N 3.43Å; L91-L93 VanDerWaalsContact C-N 3.29Å; L91-L93 PolarHBondContact O-N 2.89Å; L93-P96 WeakPolarHBondContact O-CD 3.44Å; L93-F141 VanDerWaalsContact O-CE2 3.3Å; L93-F141 WeakPolarHBondContact O-CE2 3.2Å; L93-F141 VanDerWaalsContact O-CZ 3.28Å; L93-F141 WeakPolarHBondContact O-CZ 3.4Å; L93-Y148 HydrophobicContact CD1-CD1 3.83Å; L93-Y148 HydrophobicContact CD1-CD2 4.3Å; L93-Y148 HydrophobicContact CD1-CE1 3.54Å; L93-Y148 HydrophobicContact CD1-CE2 4.06Å; L93-Y148 HydrophobicContact CD1-CG 4.2Å
94N94.6Very high92.5Very high0 Ų061.9 Ų61.90%033%0.325CS..Hα-helixtrans-86-22.1179.4-82.2-74.5000114.8H75 F78 T90 L91 G92 P96 L97 L98 Y149H75-N94 PolarHBondContact NE2-OD1 3.49Å; H75-N94 VanDerWaalsContact NE2-OD1 3.17Å; F78-N94 WeakPolarHBondContact CE2-OD1 3.24Å; T90-N94 PolarHBondContact O-N 3.05Å; T90-N94 PolarHBondContact O-ND2 2.73Å; L91-N94 CarbonylContact O-C 3.58Å; L91-N94 WeakPolarHBondContact O-CA 3.18Å; L91-N94 PolarHBondContact O-N 3.45Å; G92-N94 VanDerWaalsContact C-N 3.33Å; G92-N94 PolarHBondContact O-N 2.97Å; N94-P96 VanDerWaalsContact C-CD 3.47Å; N94-P96 VanDerWaalsContact C-N 3.35Å; N94-L97 PolarHBondContact O-N 3.5Å; N94-L97 VanDerWaalsContact O-N 3.16Å; N94-L98 WeakPolarHBondContact O-CB 3.07Å; N94-L98 PolarHBondContact O-N 2.97Å; N94-Y149 PolarHBondContact ND2-OH 3.28Å; N94-Y149 PolarHBondContact OD1-OH 3.05Å; N94-Y149 VanDerWaalsContact OD1-OH 3.09Å
95I94Very high92.1Very high91 Ų9163.2 Ų63.247%0.46732%0.319SS..Hα-helixtrans-51.7-45.2-178.5-78.4169000112.7L91 L97 L98 F99L91-I95 HydrophobicContact CG-CD1 4.43Å; L91-I95 HydrophobicContact CG-CG1 4.41Å; L91-I95 WeakPolarHBondContact O-CG1 3.34Å; L91-I95 PolarHBondContact O-N 2.8Å; I95-L97 PolarHBondContact O-N 2.99Å; I95-L98 PolarHBondContact O-N 3.4Å; I95-F99 VanDerWaalsContact O-CB 3.31Å; I95-F99 WeakPolarHBondContact O-CB 3.44Å; I95-F99 PolarHBondContact O-N 3.33Å
96P94Very high91.8Very high87 Ų8769.3 Ų69.357%0.56534%0.342SS*.Hα-helixtrans-57.8-45.3179.3-26.535.1000113.1G92 L93 N94 Y100G92-P96 WeakPolarHBondContact O-CD 3.44Å; L93-P96 WeakPolarHBondContact O-CD 3.44Å; N94-P96 VanDerWaalsContact C-CD 3.47Å; N94-P96 VanDerWaalsContact C-N 3.35Å; P96-Y100 PolarHBondContact O-N 2.97Å; P96-Y100 VanDerWaalsContact O-N 3.15Å
97L93.4Very high91.2Very high16 Ų1672.4 Ų72.48%0.08435%0.346CS..Hα-helixtrans-73.1-38.3179-175.962.1000111.6N94 I95 Y100 H101 K138 F141 Y142N94-L97 PolarHBondContact O-N 3.5Å; N94-L97 VanDerWaalsContact O-N 3.16Å; I95-L97 PolarHBondContact O-N 2.99Å; L97-Y100 HydrophobicContact CD1-CD1 4.48Å; L97-Y100 WeakPolarHBondContact O-CB 3.44Å; L97-Y100 PolarHBondContact O-N 3.24Å; L97-H101 PolarHBondContact O-N 3.46Å; L97-K138 HydrophobicContact CD1-CG 4.22Å; L97-F141 HydrophobicContact CB-CD1 4.31Å; L97-F141 HydrophobicContact CB-CE1 4.07Å; L97-F141 HydrophobicContact CB-CE2 4.35Å; L97-F141 HydrophobicContact CB-CZ 4.11Å; L97-F141 HydrophobicContact CD2-CD1 3.25Å; L97-F141 HydrophobicContact CD2-CE1 3.52Å; L97-F141 HydrophobicContact CD2-CG 3.93Å; L97-F141 HydrophobicContact CD2-CZ 4.38Å; L97-F141 HydrophobicContact CG-CD1 4.36Å; L97-F141 HydrophobicContact CG-CE1 4.43Å; L97-Y142 HydrophobicContact CD2-CD1 4.41Å; L97-Y142 HydrophobicContact CD2-CE1 3.66Å
98L93.1Very high89.9Confident40 Ų4073.5 Ų73.521%0.20935%0.348CS..Hα-helixtrans-63-45.4178.1-175.864.8000111C79 N94 I95 Y100 H101 L102C79-L98 HydrophobicContact CB-CD1 4.42Å; C79-L98 HydrophobicContact CB-CD2 4Å; N94-L98 WeakPolarHBondContact O-CB 3.07Å; N94-L98 PolarHBondContact O-N 2.97Å; I95-L98 PolarHBondContact O-N 3.4Å; L98-Y100 VanDerWaalsContact C-N 3.3Å; L98-Y100 PolarHBondContact O-N 3.4Å; L98-H101 PolarHBondContact O-N 3.02Å; L98-L102 HydrophobicContact CG-CD1 4.28Å; L98-L102 WeakPolarHBondContact O-CG 3.15Å; L98-L102 PolarHBondContact O-N 3.29Å
99F94.2Very high88.2Confident139 Ų13968.1 Ų68.161%0.6134%0.336SS*.Hα-helixtrans-60.6-42.2175.3-177.2-96.6000111I95 L102 W103I95-F99 VanDerWaalsContact O-CB 3.31Å; I95-F99 WeakPolarHBondContact O-CB 3.44Å; I95-F99 PolarHBondContact O-N 3.33Å; F99-L102 PolarHBondContact O-N 3.37Å; F99-W103 HydrophobicContact CE1-CB 4.44Å; F99-W103 VanDerWaalsContact O-CB 3.23Å; F99-W103 WeakPolarHBondContact O-CB 3.07Å; F99-W103 PolarHBondContact O-N 3.42Å
100Y91.9Very high86.2Confident54 Ų5468.1 Ų68.121%0.21235%0.347CS..Hα-helixtrans-60.1-46.8174.9-178.5-101.3000112.1P96 L97 L98 L102 W103 R104 Y130 E134P96-Y100 PolarHBondContact O-N 2.97Å; P96-Y100 VanDerWaalsContact O-N 3.15Å; L97-Y100 HydrophobicContact CD1-CD1 4.48Å; L97-Y100 WeakPolarHBondContact O-CB 3.44Å; L97-Y100 PolarHBondContact O-N 3.24Å; L98-Y100 VanDerWaalsContact C-N 3.3Å; L98-Y100 PolarHBondContact O-N 3.4Å; Y100-L102 PolarHBondContact O-N 3.14Å; Y100-W103 HydrophobicContact CD2-CE3 4.47Å; Y100-W103 HydrophobicContact CE2-CE3 4.41Å; Y100-W103 HydrophobicContact CE2-CZ3 4.42Å; Y100-W103 PolarHBondContact O-N 3.35Å; Y100-R104 WeakPolarHBondContact O-CB 3.26Å; Y100-R104 PolarHBondContact O-N 3.48Å; Y100-Y130 PolarHBondContact OH-OH 2.99Å; Y100-E134 HydrophobicContact CE1-CG 3.97Å; Y100-E134 WeakPolarHBondContact CE1-OE1 3.49Å; Y100-E134 WeakPolarHBondContact OH-CG 3.39Å; Y100-E134 PolarHBondContact OH-OE1 3.04Å; Y100-E134 PolarHBondContact OH-OE2 2.92Å
101H91.8Very high83.8Confident5 Ų575 Ų752%0.02338%0.383CS..Hα-helixtrans-60.3-43.9176.2-69.7160.8000112.7E71 Y72 H75 L97 L98 R104 Y105 Y142E71-H101 IonicContact OE1-NE2 3.82Å; Y72-H101 HydrophobicContact CD1-CB 4.01Å; Y72-H101 AromaticContact CD1-CD2 3.4Å; Y72-H101 VanDerWaalsContact CD1-CD2 3.4Å; Y72-H101 WeakPolarHBondContact CD1-CD2 3.5Å; Y72-H101 AromaticContact CD1-CE1 3.99Å; Y72-H101 AromaticContact CD1-CG 3.53Å; Y72-H101 AromaticContact CD1-ND1 3.9Å; Y72-H101 AromaticContact CD1-NE2 3.73Å; Y72-H101 HydrophobicContact CD2-CB 4.49Å; Y72-H101 HydrophobicContact CE1-CB 4.36Å; Y72-H101 AromaticContact CE1-CD2 3.2Å; Y72-H101 WeakPolarHBondContact CE1-CD2 3.43Å; Y72-H101 AromaticContact CE1-CG 3.8Å; Y72-H101 AromaticContact CE1-NE2 3.61Å; Y72-H101 HydrophobicContact CG-CB 4.1Å; Y72-H101 AromaticContact CZ-CD2 3.98Å; H75-H101 AromaticContact CE1-ND1 3.98Å; H75-H101 AromaticContact CG-CE1 3.73Å; H75-H101 AromaticContact CG-ND1 3.51Å; H75-H101 AromaticContact ND1-CE1 3.73Å; H75-H101 AromaticContact ND1-ND1 3.14Å; H75-H101 PolarHBondContact ND1-ND1 3.46Å; H75-H101 VanDerWaalsContact ND1-ND1 3.14Å; L97-H101 PolarHBondContact O-N 3.46Å; L98-H101 PolarHBondContact O-N 3.02Å; H101-R104 PolarHBondContact O-N 2.87Å; H101-Y105 VanDerWaalsContact O-CB 3.24Å; H101-Y105 WeakPolarHBondContact O-CB 3.23Å; H101-Y105 PolarHBondContact O-N 2.87Å; H101-Y142 PolarHBondContact CE1-OH 3.34Å
102L90.9Very high81.5Confident83 Ų8376.6 Ų76.644%0.43541%0.405SS..Hα-helixtrans-65.8-48.3177.5-70.4173.7000111.6L98 F99 Y100 R104 Y105 F106L98-L102 HydrophobicContact CG-CD1 4.28Å; L98-L102 WeakPolarHBondContact O-CG 3.15Å; L98-L102 PolarHBondContact O-N 3.29Å; F99-L102 PolarHBondContact O-N 3.37Å; Y100-L102 PolarHBondContact O-N 3.14Å; L102-R104 VanDerWaalsContact C-N 3.28Å; L102-R104 PolarHBondContact O-N 2.95Å; L102-Y105 WeakPolarHBondContact O-CB 3.43Å; L102-Y105 PolarHBondContact O-N 3.02Å; L102-Y105 VanDerWaalsContact O-N 3.1Å; L102-F106 HydrophobicContact CB-CD2 4.41Å; L102-F106 HydrophobicContact CB-CE2 4.31Å; L102-F106 HydrophobicContact CD2-CE2 4.22Å; L102-F106 WeakPolarHBondContact O-CD2 3.33Å; L102-F106 PolarHBondContact O-N 3.45Å
103W90.2Very high79.1Confident103 Ų10378.5 Ų78.539%0.3941%0.412SS..Hα-helixtrans-56.3-46.7177178.180.4000110.8F99 Y100 Y105 F106 H107F99-W103 HydrophobicContact CE1-CB 4.44Å; F99-W103 VanDerWaalsContact O-CB 3.23Å; F99-W103 WeakPolarHBondContact O-CB 3.07Å; F99-W103 PolarHBondContact O-N 3.42Å; Y100-W103 HydrophobicContact CD2-CE3 4.47Å; Y100-W103 HydrophobicContact CE2-CE3 4.41Å; Y100-W103 HydrophobicContact CE2-CZ3 4.42Å; Y100-W103 PolarHBondContact O-N 3.35Å; W103-Y105 VanDerWaalsContact C-N 3.33Å; W103-Y105 PolarHBondContact O-N 2.97Å; W103-F106 PolarHBondContact O-N 3.16Å; W103-H107 AromaticContact CD1-CE1 3.11Å; W103-H107 AromaticContact CD1-ND1 3.2Å; W103-H107 AromaticContact CD1-NE2 3.85Å; W103-H107 AromaticContact CE2-CG 3.88Å; W103-H107 AromaticContact CE2-ND1 3.82Å; W103-H107 AromaticContact CG-ND1 3.72Å; W103-H107 AromaticContact NE1-CD2 3.67Å; W103-H107 AromaticContact NE1-CE1 3.08Å; W103-H107 PolarHBondContact NE1-CE1 2.84Å; W103-H107 AromaticContact NE1-CG 3.6Å; W103-H107 AromaticContact NE1-ND1 3.22Å; W103-H107 PolarHBondContact NE1-ND1 3.47Å; W103-H107 AromaticContact NE1-NE2 3.33Å; W103-H107 PolarHBondContact NE1-NE2 3.42Å; W103-H107 WeakPolarHBondContact O-CB 3.38Å; W103-H107 PolarHBondContact O-N 2.95Å; W103-H107 PolarHBondContact O-ND1 3.4Å
104R86.1Confident76.8Confident59 Ų5981.1 Ų81.122%0.22342%0.422CS..Hα-helixtrans-68-29.9178.2-172.548.2170.3-177.52.5112.5Y72 Y100 H101 L102 R108 M116Y72-R104 WeakPolarHBondContact OH-CG 3.38Å; Y100-R104 WeakPolarHBondContact O-CB 3.26Å; Y100-R104 PolarHBondContact O-N 3.48Å; H101-R104 PolarHBondContact O-N 2.87Å; L102-R104 VanDerWaalsContact C-N 3.28Å; L102-R104 PolarHBondContact O-N 2.95Å; R104-R108 WeakPolarHBondContact O-CG 3.47Å; R104-M116 HydrophobicContact CB-CE 4.36Å; R104-M116 HydrophobicContact CG-CE 3.42Å; R104-M116 VanDerWaalsContact CG-CE 3.42Å; R104-M116 WeakPolarHBondContact O-CE 3.12Å
105Y85Confident74.9Confident114 Ų11483.5 Ų83.545%0.44744%0.437SS..Hα-helixtrans-72.1-41.4173.2-175-84.3000112.3Y72 H101 L102 W103 R108Y72-Y105 HydrophobicContact CD2-CD2 4.45Å; H101-Y105 VanDerWaalsContact O-CB 3.24Å; H101-Y105 WeakPolarHBondContact O-CB 3.23Å; H101-Y105 PolarHBondContact O-N 2.87Å; L102-Y105 WeakPolarHBondContact O-CB 3.43Å; L102-Y105 PolarHBondContact O-N 3.02Å; L102-Y105 VanDerWaalsContact O-N 3.1Å; W103-Y105 VanDerWaalsContact C-N 3.33Å; W103-Y105 PolarHBondContact O-N 2.97Å; Y105-R108 WeakPolarHBondContact O-CD 3.25Å; Y105-R108 VanDerWaalsContact O-CG 3.23Å; Y105-R108 WeakPolarHBondContact O-CG 3.29Å
106F85.2Confident73.1Confident147 Ų14780.1 Ų80.165%0.64542%0.419SS*.Hα-helixtrans-82.5-35.3-177.9-70.3-61.4000113.9L102 W103 R108L102-F106 HydrophobicContact CB-CD2 4.41Å; L102-F106 HydrophobicContact CB-CE2 4.31Å; L102-F106 HydrophobicContact CD2-CE2 4.22Å; L102-F106 WeakPolarHBondContact O-CD2 3.33Å; L102-F106 PolarHBondContact O-N 3.45Å; W103-F106 PolarHBondContact O-N 3.16Å; F106-R108 PolarHBondContact O-N 3.25Å
107H79.6Confident71.6Confident123 Ų12376.8 Ų76.857%0.56940%0.395SS*.THydrogen-bonded Turntrans-80.828.5176.9-67.271.5000112.4W103W103-H107 AromaticContact CD1-CE1 3.11Å; W103-H107 AromaticContact CD1-ND1 3.2Å; W103-H107 AromaticContact CD1-NE2 3.85Å; W103-H107 AromaticContact CE2-CG 3.88Å; W103-H107 AromaticContact CE2-ND1 3.82Å; W103-H107 AromaticContact CG-ND1 3.72Å; W103-H107 AromaticContact NE1-CD2 3.67Å; W103-H107 AromaticContact NE1-CE1 3.08Å; W103-H107 PolarHBondContact NE1-CE1 2.84Å; W103-H107 AromaticContact NE1-CG 3.6Å; W103-H107 AromaticContact NE1-ND1 3.22Å; W103-H107 PolarHBondContact NE1-ND1 3.47Å; W103-H107 AromaticContact NE1-NE2 3.33Å; W103-H107 PolarHBondContact NE1-NE2 3.42Å; W103-H107 WeakPolarHBondContact O-CB 3.38Å; W103-H107 PolarHBondContact O-N 2.95Å; W103-H107 PolarHBondContact O-ND1 3.4Å
108R63.5Low70.5Confident70 Ų7078.7 Ų78.726%0.26441%0.406SS..SBendtrans-76.6131.4168-68.2175.3-179.5161.7-1107.8R104 Y105 F106 A110 M116R104-R108 WeakPolarHBondContact O-CG 3.47Å; Y105-R108 WeakPolarHBondContact O-CD 3.25Å; Y105-R108 VanDerWaalsContact O-CG 3.23Å; Y105-R108 WeakPolarHBondContact O-CG 3.29Å; F106-R108 PolarHBondContact O-N 3.25Å; R108-A110 PolarHBondContact O-N 2.95Å; R108-M116 HydrophobicContact CG-CE 4.05Å; R108-M116 PolarHBondContact NE-SD 3.43Å
109P56.1Low69.4Low61 Ų6177.8 Ų77.840%0.39640%0.404SS..  trans-60.5124.1170.721.6-26.9000109D111 E114P109-D111 PolarHBondContact O-N 3.31Å; P109-E114 HydrophobicContact CG-CB 3.65Å; P109-E114 VanDerWaalsContact CG-O 3.27Å; P109-E114 WeakPolarHBondContact CG-O 3.41Å
110A51Low68.5Low101 Ų10176.6 Ų76.684%0.83541%0.408SS*.THydrogen-bonded Turntrans-67.5-17.9-177.100000112.9R108 G112R108-A110 PolarHBondContact O-N 2.95Å; A110-G112 PolarHBondContact O-N 3.47Å; A110-G112 VanDerWaalsContact O-N 3.07Å
111D44.4Very low67.8Low143 Ų14375.7 Ų75.777%0.76541%0.41SS*.THydrogen-bonded Turntrans-74.52.8-171.7-62.9-22.4000114.2P109 S113P109-D111 PolarHBondContact O-N 3.31Å; D111-S113 PolarHBondContact O-N 3.45Å
112G45.2Very low67.1Low54 Ų5475.7 Ų75.756%0.55741%0.41SS*.SBendtrans64.65.4175.500000114.9A110 V115A110-G112 PolarHBondContact O-N 3.47Å; A110-G112 VanDerWaalsContact O-N 3.07Å; G112-V115 WeakPolarHBondContact O-CG2 3.24Å
113S43.5Very low66.3Low76 Ų7676.5 Ų76.553%0.53141%0.413SS..SBendtrans-98.9-38.2-174.855.30000113.6D111D111-S113 PolarHBondContact O-N 3.45Å
114E44.3Very low66Low137 Ų13775.3 Ų75.364%0.6441%0.414SS*.SBendtrans-106.651.9175.1-70.7-175.3-173.200111P109P109-E114 HydrophobicContact CG-CB 3.65Å; P109-E114 VanDerWaalsContact CG-O 3.27Å; P109-E114 WeakPolarHBondContact CG-O 3.41Å
115V54.7Low65.9Low50 Ų5074 Ų7430%0.30342%0.415SS..  trans-56.1143.3178.2-177.20000109.5R65 G112 Y117 D118R65-V115 HydrophobicContact CG-CG1 4.29Å; G112-V115 WeakPolarHBondContact O-CG2 3.24Å; V115-Y117 CarbonylContact O-C 3.56Å; V115-Y117 PolarHBondContact O-N 3.18Å; V115-D118 PolarHBondContact O-N 2.97Å
116M57.3Low66Low20 Ų2074.3 Ų74.310%0.09943%0.425CS..THydrogen-bonded Turntrans-43.9110.4171.3-79.2-175.8167.500109.8V68 Y72 R104 R108V68-M116 HydrophobicContact CG1-SD 4.02Å; V68-M116 HydrophobicContact CG2-SD 4.24Å; Y72-M116 HydrophobicContact CE2-CE 4.22Å; R104-M116 HydrophobicContact CB-CE 4.36Å; R104-M116 HydrophobicContact CG-CE 3.42Å; R104-M116 VanDerWaalsContact CG-CE 3.42Å; R104-M116 WeakPolarHBondContact O-CE 3.12Å; R108-M116 HydrophobicContact CG-CE 4.05Å; R108-M116 PolarHBondContact NE-SD 3.43Å
117Y61.8Low66.1Low17 Ų1770.5 Ų70.57%0.06741%0.411CS..THydrogen-bonded Turntrans72.348-175.2-41.7-68.2000115.3F31 C61 L64 V68 V115 A119 I122 C131F31-Y117 AromaticContact CE1-CD1 3.9Å; F31-Y117 HydrophobicContact CE1-CD1 3.9Å; F31-Y117 AromaticContact CE1-CE1 3.6Å; F31-Y117 HydrophobicContact CE1-CE1 3.6Å; F31-Y117 HydrophobicContact CZ-CD1 4Å; F31-Y117 AromaticContact CZ-CE1 3.28Å; F31-Y117 HydrophobicContact CZ-CE1 3.28Å; F31-Y117 AromaticContact CZ-CZ 3.73Å; C61-Y117 WeakPolarHBondContact CB-O 3.37Å; L64-Y117 HydrophobicContact CB-CD2 3.88Å; L64-Y117 HydrophobicContact CB-CE2 4.29Å; L64-Y117 HydrophobicContact CB-CG 4.18Å; V68-Y117 HydrophobicContact CB-CE2 4.35Å; V68-Y117 HydrophobicContact CG1-CE2 4.49Å; V115-Y117 CarbonylContact O-C 3.56Å; V115-Y117 PolarHBondContact O-N 3.18Å; Y117-A119 PolarHBondContact O-N 3.36Å; Y117-I122 HydrophobicContact CD1-CD1 3.99Å; Y117-I122 HydrophobicContact CD1-CG1 4.33Å; Y117-I122 HydrophobicContact CE1-CD1 4.49Å; Y117-C131 HydrophobicContact CE1-CB 4.45Å
118D70.8Confident66.5Low56 Ų5664.9 Ų64.930%0.29939%0.385SS..  trans-63134161.4173.350.8000109.9V115 V120 S121 I122V115-D118 PolarHBondContact O-N 2.97Å; D118-V120 PolarHBondContact O-N 3.49Å; D118-V120 WeakPolarHBondContact OD2-CB 3.34Å; D118-V120 PolarHBondContact OD2-N 2.94Å; D118-S121 PolarHBondContact O-N 3.47Å; D118-S121 VanDerWaalsContact O-N 3.14Å; D118-S121 PolarHBondContact O-OG 3.19Å; D118-S121 PolarHBondContact OD2-N 3.02Å; D118-I122 WeakPolarHBondContact O-CG2 3.27Å; D118-I122 PolarHBondContact O-N 3.2Å
119A71.1Confident67.8Low21 Ų2165 Ų6517%0.17439%0.39CS..Hα-helixtrans-60.7-33-17200000112.2I57 E58 Y117 M123I57-A119 HydrophobicContact CG2-CB 4.34Å; E58-A119 HydrophobicContact CG-CB 4.46Å; Y117-A119 PolarHBondContact O-N 3.36Å; A119-M123 WeakPolarHBondContact O-CB 3.36Å
120V75Confident69.4Low114 Ų11467.5 Ų67.569%0.69139%0.393SS*.Hα-helixtrans-73.5-46.4177.8-174.60000110.2D118D118-V120 PolarHBondContact O-N 3.49Å; D118-V120 WeakPolarHBondContact OD2-CB 3.34Å; D118-V120 PolarHBondContact OD2-N 2.94Å
121S76.5Confident71.2Confident36 Ų3662.9 Ų62.925%0.25235%0.354SS..Hα-helixtrans-66-45.1-179.672.80000113.3D118 M123 N124 I127D118-S121 PolarHBondContact O-N 3.47Å; D118-S121 VanDerWaalsContact O-N 3.14Å; D118-S121 PolarHBondContact O-OG 3.19Å; D118-S121 PolarHBondContact OD2-N 3.02Å; S121-M123 PolarHBondContact O-N 3.43Å; S121-N124 WeakPolarHBondContact O-CB 3.31Å; S121-N124 PolarHBondContact O-N 2.86Å; S121-N124 VanDerWaalsContact O-N 3.08Å; S121-I127 WeakPolarHBondContact O-CD1 3.44Å
122I77.4Confident73.5Confident4 Ų457 Ų572%0.02132%0.322CS..Hα-helixtrans-70.5-21.6-175.3-164.456.9000112.4F31 L34 Y117 D118 N124 I127 L128 C131F31-I122 HydrophobicContact CE1-CD1 4.11Å; F31-I122 HydrophobicContact CE1-CG1 4.47Å; L34-I122 HydrophobicContact CD1-CG1 4.23Å; Y117-I122 HydrophobicContact CD1-CD1 3.99Å; Y117-I122 HydrophobicContact CD1-CG1 4.33Å; Y117-I122 HydrophobicContact CE1-CD1 4.49Å; D118-I122 WeakPolarHBondContact O-CG2 3.27Å; D118-I122 PolarHBondContact O-N 3.2Å; I122-N124 PolarHBondContact O-N 3.04Å; I122-I127 HydrophobicContact CD1-CG2 4.09Å; I122-L128 HydrophobicContact CD1-CD1 4.27Å; I122-L128 HydrophobicContact CG1-CD1 4.29Å; I122-C131 HydrophobicContact CD1-CB 4.11Å
123M74.4Confident75.8Confident101 Ų10161.7 Ų61.750%0.49833%0.327SS..THydrogen-bonded Turntrans-74-9.6175.1-165.7177.165.300112.2F38 A119 S121 A125F38-M123 HydrophobicContact CD2-CG 4.01Å; F38-M123 WeakPolarHBondContact CD2-O 3.31Å; F38-M123 WeakPolarHBondContact CE2-O 3.47Å; A119-M123 WeakPolarHBondContact O-CB 3.36Å; S121-M123 PolarHBondContact O-N 3.43Å; M123-A125 PolarHBondContact O-N 3.45Å
124N82.9Confident78.1Confident78 Ų7858.7 Ų58.742%0.41731%0.305SS..SBendtrans-69.5126.3168.8-173.3-4.7000110.2S121 I122 D126 I127 L128S121-N124 WeakPolarHBondContact O-CB 3.31Å; S121-N124 PolarHBondContact O-N 2.86Å; S121-N124 VanDerWaalsContact O-N 3.08Å; I122-N124 PolarHBondContact O-N 3.04Å; N124-D126 VanDerWaalsContact C-N 3.25Å; N124-D126 PolarHBondContact O-N 3Å; N124-D126 PolarHBondContact OD1-N 2.93Å; N124-I127 HydrophobicContact CB-CB 4.26Å; N124-I127 HydrophobicContact CB-CD1 3.98Å; N124-I127 HydrophobicContact CB-CG1 4.08Å; N124-I127 PolarHBondContact O-N 2.86Å; N124-I127 VanDerWaalsContact O-N 3.11Å; N124-L128 PolarHBondContact O-N 3.36Å
125A84.7Confident80.5Confident31 Ų3152.4 Ų52.426%0.25628%0.276SS..Hα-helixtrans-54.3-38.7-177.100000113.4F38 M123 N129F38-A125 HydrophobicContact CE1-CB 4Å; F38-A125 HydrophobicContact CE2-CB 4.47Å; F38-A125 HydrophobicContact CZ-CB 3.81Å; M123-A125 PolarHBondContact O-N 3.45Å; A125-N129 WeakPolarHBondContact O-CB 3.41Å; A125-N129 VanDerWaalsContact O-CG 3.28Å; A125-N129 PolarHBondContact O-N 2.93Å; A125-N129 PolarHBondContact O-ND2 3.33Å
126D86.8Confident82.5Confident121 Ų12156.7 Ų56.765%0.64729%0.287SS*.Hα-helixtrans-69-41.1-179.4-66.7-30000111.8N124 Y130N124-D126 VanDerWaalsContact C-N 3.25Å; N124-D126 PolarHBondContact O-N 3Å; N124-D126 PolarHBondContact OD1-N 2.93Å; D126-Y130 WeakPolarHBondContact O-CB 3.39Å; D126-Y130 PolarHBondContact O-N 3.23Å
127I87.1Confident84.4Confident67 Ų6759.3 Ų59.334%0.34431%0.306SS..Hα-helixtrans-68.4-43.7178.2-61.5178.7000109.8S121 I122 N124 N129 Y130 C131S121-I127 WeakPolarHBondContact O-CD1 3.44Å; I122-I127 HydrophobicContact CD1-CG2 4.09Å; N124-I127 HydrophobicContact CB-CB 4.26Å; N124-I127 HydrophobicContact CB-CD1 3.98Å; N124-I127 HydrophobicContact CB-CG1 4.08Å; N124-I127 PolarHBondContact O-N 2.86Å; N124-I127 VanDerWaalsContact O-N 3.11Å; I127-N129 PolarHBondContact O-N 2.87Å; I127-Y130 WeakPolarHBondContact O-CB 2.99Å; I127-Y130 PolarHBondContact O-N 3.28Å; I127-C131 PolarHBondContact O-N 3.41Å; I127-C131 PolarHBondContact O-SG 2.91Å
128L87.9Confident86Confident5 Ų558.9 Ų58.93%0.02631%0.305CS..Hα-helixtrans-61.6-44.8177.7-173.858.9000111.9F31 L34 R35 I122 N124 Y130 C131 Q132F31-L128 HydrophobicContact CB-CD1 4.39Å; F31-L128 HydrophobicContact CD1-CD1 3.84Å; L34-L128 HydrophobicContact CB-CD1 4.12Å; R35-L128 HydrophobicContact CB-CD2 3.86Å; R35-L128 HydrophobicContact CG-CD2 4.36Å; I122-L128 HydrophobicContact CD1-CD1 4.27Å; I122-L128 HydrophobicContact CG1-CD1 4.29Å; N124-L128 PolarHBondContact O-N 3.36Å; L128-Y130 VanDerWaalsContact C-N 3.32Å; L128-Y130 PolarHBondContact O-N 3.48Å; L128-C131 PolarHBondContact O-N 3.31Å; L128-Q132 WeakPolarHBondContact O-CB 3.43Å; L128-Q132 PolarHBondContact O-N 3.32Å
129N90.2Very high87.3Confident71 Ų7157.6 Ų57.638%0.3830%0.298SS..Hα-helixtrans-62.2-39.7176.1-78.2-38.6000111.8A125 I127 K133A125-N129 WeakPolarHBondContact O-CB 3.41Å; A125-N129 VanDerWaalsContact O-CG 3.28Å; A125-N129 PolarHBondContact O-N 2.93Å; A125-N129 PolarHBondContact O-ND2 3.33Å; I127-N129 PolarHBondContact O-N 2.87Å; N129-K133 WeakPolarHBondContact O-CB 3.46Å; N129-K133 PolarHBondContact O-N 3.34Å
130Y90.5Very high88.5Confident114 Ų11459.4 Ų59.445%0.44731%0.313SS..Hα-helixtrans-60.7-50.6173.8174.1-90.4000111.7Y100 D126 I127 L128 Q132 K133 E134Y100-Y130 PolarHBondContact OH-OH 2.99Å; D126-Y130 WeakPolarHBondContact O-CB 3.39Å; D126-Y130 PolarHBondContact O-N 3.23Å; I127-Y130 WeakPolarHBondContact O-CB 2.99Å; I127-Y130 PolarHBondContact O-N 3.28Å; L128-Y130 VanDerWaalsContact C-N 3.32Å; L128-Y130 PolarHBondContact O-N 3.48Å; Y130-Q132 VanDerWaalsContact C-N 3.33Å; Y130-Q132 PolarHBondContact O-N 3.01Å; Y130-K133 PolarHBondContact O-N 3.01Å; Y130-E134 WeakPolarHBondContact O-CB 3.15Å; Y130-E134 PolarHBondContact O-N 3.49Å
131C89.7Confident89.5Confident4 Ų456.3 Ų56.33%0.02729%0.29CS..Hα-helixtrans-64.3-35.7179.9-71.50000113.1F31 Y117 I122 I127 L128 S135F31-C131 HydrophobicContact CD1-CB 4.23Å; F31-C131 HydrophobicContact CE1-CB 3.82Å; F31-C131 HydrophobicContact CE2-CB 4.41Å; F31-C131 HydrophobicContact CZ-CB 3.96Å; Y117-C131 HydrophobicContact CE1-CB 4.45Å; I122-C131 HydrophobicContact CD1-CB 4.11Å; I127-C131 PolarHBondContact O-N 3.41Å; I127-C131 PolarHBondContact O-SG 2.91Å; L128-C131 PolarHBondContact O-N 3.31Å; C131-S135 PolarHBondContact O-N 3.13Å; C131-S135 PolarHBondContact O-OG 2.94Å
132Q91.5Very high90.4Very high21 Ų2154.6 Ų54.610%0.09828%0.278CS..Hα-helixtrans-65.1-47.5174.4-169.6170.216.900110.3L128 Y130 E134 S135 W136L128-Q132 WeakPolarHBondContact O-CB 3.43Å; L128-Q132 PolarHBondContact O-N 3.32Å; Y130-Q132 VanDerWaalsContact C-N 3.33Å; Y130-Q132 PolarHBondContact O-N 3.01Å; Q132-E134 PolarHBondContact O-N 3.25Å; Q132-S135 PolarHBondContact O-N 2.98Å; Q132-W136 PolarHBondContact O-N 3.19Å
133K94Very high91.4Very high152 Ų15258.5 Ų58.566%0.66130%0.299SS*.Hα-helixtrans-61.3-42.4176.9-172176.2179.2-178.60112N129 Y130 S135 W136 C137N129-K133 WeakPolarHBondContact O-CB 3.46Å; N129-K133 PolarHBondContact O-N 3.34Å; Y130-K133 PolarHBondContact O-N 3.01Å; K133-S135 VanDerWaalsContact C-N 3.32Å; K133-S135 PolarHBondContact O-N 3.11Å; K133-W136 PolarHBondContact O-N 2.95Å; K133-C137 PolarHBondContact O-N 3.22Å; K133-C137 PolarHBondContact O-SG 2.89Å
134E92.4Very high92.4Very high13 Ų1360 Ų606%0.06131%0.308CS..Hα-helixtrans-54.4-48.6173.3-177.6-168.6155.900111.1Y100 Y130 Q132 W136 C137 K138Y100-E134 HydrophobicContact CE1-CG 3.97Å; Y100-E134 WeakPolarHBondContact CE1-OE1 3.49Å; Y100-E134 WeakPolarHBondContact OH-CG 3.39Å; Y100-E134 PolarHBondContact OH-OE1 3.04Å; Y100-E134 PolarHBondContact OH-OE2 2.92Å; Y130-E134 WeakPolarHBondContact O-CB 3.15Å; Y130-E134 PolarHBondContact O-N 3.49Å; Q132-E134 PolarHBondContact O-N 3.25Å; E134-W136 PolarHBondContact O-N 3.42Å; E134-C137 PolarHBondContact O-N 3.35Å; E134-K138 HydrophobicContact CG-CD 4.45Å; E134-K138 WeakPolarHBondContact O-CG 3.38Å; E134-K138 PolarHBondContact O-N 3.45Å; E134-K138 VanDerWaalsContact OE1-CE 3.24Å; E134-K138 WeakPolarHBondContact OE1-CE 3.49Å; E134-K138 IonicContact OE1-NZ 3.71Å; E134-K138 PolarHBondContact OE1-NZ 3.48Å
135S94.3Very high93Very high4 Ų456.6 Ų56.63%0.02829%0.291CS..Hα-helixtrans-65.2-39.9-178.9-55.90000112.5V24 F31 C131 Q132 K133 K138 L139V24-S135 VanDerWaalsContact CG1-O 3.29Å; V24-S135 WeakPolarHBondContact CG1-O 3.36Å; F31-S135 WeakPolarHBondContact CD2-OG 3.4Å; F31-S135 WeakPolarHBondContact CE2-OG 3.31Å; C131-S135 PolarHBondContact O-N 3.13Å; C131-S135 PolarHBondContact O-OG 2.94Å; Q132-S135 PolarHBondContact O-N 2.98Å; K133-S135 VanDerWaalsContact C-N 3.32Å; K133-S135 PolarHBondContact O-N 3.11Å; S135-K138 PolarHBondContact O-N 3.28Å; S135-L139 PolarHBondContact O-N 3Å
136W97.1Very high93.5Very high140 Ų14057.7 Ų57.753%0.5329%0.29SS..Hα-helixtrans-65-40.9173.8-82.6104.8000112.8I28 Q132 K133 E134 L139 A140I28-W136 HydrophobicContact CD1-CD2 4.2Å; I28-W136 HydrophobicContact CD1-CE3 4.43Å; I28-W136 HydrophobicContact CG2-CZ2 4Å; Q132-W136 PolarHBondContact O-N 3.19Å; K133-W136 PolarHBondContact O-N 2.95Å; E134-W136 PolarHBondContact O-N 3.42Å; W136-L139 HydrophobicContact CE3-CD2 4.18Å; W136-L139 HydrophobicContact CZ3-CD2 4.1Å; W136-L139 PolarHBondContact O-N 2.9Å; W136-A140 PolarHBondContact O-N 3.22Å
137C96.3Very high93.9Very high75 Ų7558 Ų5851%0.50729%0.286SS..Hα-helixtrans-62.5-42.6175.4-72.30000111.6K133 E134 A140 F141K133-C137 PolarHBondContact O-N 3.22Å; K133-C137 PolarHBondContact O-SG 2.89Å; E134-C137 PolarHBondContact O-N 3.35Å; C137-A140 PolarHBondContact O-N 3.04Å; C137-F141 PolarHBondContact O-N 3.14Å
138K95.3Very high94.4Very high8 Ų857.8 Ų57.84%0.03528%0.281CS..Hα-helixtrans-62.3-43.1174.7-71.9172.8177.7174.10112.3V24 E71 L97 E134 S135 A140 F141 Y142V24-K138 HydrophobicContact CG1-CB 4.3Å; V24-K138 HydrophobicContact CG2-CB 4.3Å; E71-K138 WeakPolarHBondContact OE1-CD 3.37Å; E71-K138 IonicContact OE1-NZ 3.94Å; L97-K138 HydrophobicContact CD1-CG 4.22Å; E134-K138 HydrophobicContact CG-CD 4.45Å; E134-K138 WeakPolarHBondContact O-CG 3.38Å; E134-K138 PolarHBondContact O-N 3.45Å; E134-K138 VanDerWaalsContact OE1-CE 3.24Å; E134-K138 WeakPolarHBondContact OE1-CE 3.49Å; E134-K138 IonicContact OE1-NZ 3.71Å; E134-K138 PolarHBondContact OE1-NZ 3.48Å; S135-K138 PolarHBondContact O-N 3.28Å; K138-A140 VanDerWaalsContact C-N 3.35Å; K138-A140 PolarHBondContact O-N 3.08Å; K138-F141 PolarHBondContact O-N 3.37Å; K138-Y142 HydrophobicContact CB-CD2 4.49Å; K138-Y142 HydrophobicContact CB-CE2 4.25Å; K138-Y142 WeakPolarHBondContact O-CD2 3.5Å; K138-Y142 PolarHBondContact O-N 2.77Å
139L97.3Very high94.7Very high29 Ų2957.6 Ų57.615%0.15228%0.28CS..Hα-helixtrans-58.9-48.4177.2-17963.6000110.8I21 V24 I25 I28 S135 W136 F141 Y142 L143I21-L139 HydrophobicContact CG2-CD1 4.2Å; V24-L139 HydrophobicContact CG1-CB 3.71Å; V24-L139 HydrophobicContact CG1-CD1 4.34Å; I25-L139 HydrophobicContact CG1-CD1 4.04Å; I28-L139 HydrophobicContact CD1-CB 3.99Å; I28-L139 HydrophobicContact CD1-CD2 3.59Å; I28-L139 HydrophobicContact CD1-CG 4.34Å; S135-L139 PolarHBondContact O-N 3Å; W136-L139 HydrophobicContact CE3-CD2 4.18Å; W136-L139 HydrophobicContact CZ3-CD2 4.1Å; W136-L139 PolarHBondContact O-N 2.9Å; L139-F141 VanDerWaalsContact C-N 3.32Å; L139-F141 PolarHBondContact O-N 3.45Å; L139-Y142 PolarHBondContact O-N 3.14Å; L139-L143 VanDerWaalsContact O-CB 3.25Å; L139-L143 WeakPolarHBondContact O-CB 3.41Å; L139-L143 PolarHBondContact O-N 2.92Å
140A97Very high94.9Very high60 Ų6058 Ų5850%0.49628%0.282SS..Hα-helixtrans-60.1-42.6177.900000111.8W136 C137 K138 L143 L144W136-A140 PolarHBondContact O-N 3.22Å; C137-A140 PolarHBondContact O-N 3.04Å; K138-A140 VanDerWaalsContact C-N 3.35Å; K138-A140 PolarHBondContact O-N 3.08Å; A140-L143 PolarHBondContact O-N 3.29Å; A140-L144 WeakPolarHBondContact O-CB 3.37Å; A140-L144 PolarHBondContact O-N 2.91Å
141F96.5Very high95.2Very high49 Ų4959.7 Ų59.722%0.21529%0.288CS..Hα-helixtrans-61.3-50.1176.7-178.7-86.2000112.1L93 L97 C137 K138 L139 L143 L144 S145L93-F141 VanDerWaalsContact O-CE2 3.3Å; L93-F141 WeakPolarHBondContact O-CE2 3.2Å; L93-F141 VanDerWaalsContact O-CZ 3.28Å; L93-F141 WeakPolarHBondContact O-CZ 3.4Å; L97-F141 HydrophobicContact CB-CD1 4.31Å; L97-F141 HydrophobicContact CB-CE1 4.07Å; L97-F141 HydrophobicContact CB-CE2 4.35Å; L97-F141 HydrophobicContact CB-CZ 4.11Å; L97-F141 HydrophobicContact CD2-CD1 3.25Å; L97-F141 HydrophobicContact CD2-CE1 3.52Å; L97-F141 HydrophobicContact CD2-CG 3.93Å; L97-F141 HydrophobicContact CD2-CZ 4.38Å; L97-F141 HydrophobicContact CG-CD1 4.36Å; L97-F141 HydrophobicContact CG-CE1 4.43Å; C137-F141 PolarHBondContact O-N 3.14Å; K138-F141 PolarHBondContact O-N 3.37Å; L139-F141 VanDerWaalsContact C-N 3.32Å; L139-F141 PolarHBondContact O-N 3.45Å; F141-L143 PolarHBondContact O-N 3.11Å; F141-L144 PolarHBondContact O-N 3.19Å; F141-S145 WeakPolarHBondContact CE1-OG 3.32Å; F141-S145 WeakPolarHBondContact O-CB 3.45Å; F141-S145 PolarHBondContact O-N 3.33Å; F141-S145 PolarHBondContact O-OG 3.41Å
142Y96.3Very high95.3Very high0 Ų059.9 Ų59.90%029%0.289CS..Hα-helixtrans-65.8-38.6-180-68.9-46.1000112.2L20 V24 H75 L97 H101 K138 L139 S145 F146L20-Y142 HydrophobicContact CB-CD2 4.38Å; L20-Y142 HydrophobicContact CB-CE2 4.25Å; L20-Y142 HydrophobicContact CD1-CD1 4.45Å; L20-Y142 HydrophobicContact CD1-CE1 3.86Å; V24-Y142 HydrophobicContact CG2-CD2 3.69Å; V24-Y142 HydrophobicContact CG2-CE2 3.54Å; H75-Y142 AromaticContact CD2-CE1 3.71Å; L97-Y142 HydrophobicContact CD2-CD1 4.41Å; L97-Y142 HydrophobicContact CD2-CE1 3.66Å; H101-Y142 PolarHBondContact CE1-OH 3.34Å; K138-Y142 HydrophobicContact CB-CD2 4.49Å; K138-Y142 HydrophobicContact CB-CE2 4.25Å; K138-Y142 WeakPolarHBondContact O-CD2 3.5Å; K138-Y142 PolarHBondContact O-N 2.77Å; L139-Y142 PolarHBondContact O-N 3.14Å; Y142-S145 PolarHBondContact O-N 3.04Å; Y142-F146 VanDerWaalsContact O-CB 3.25Å; Y142-F146 WeakPolarHBondContact O-CB 3.34Å; Y142-F146 PolarHBondContact O-N 3.15Å
143L96.4Very high95.4Very high86 Ų8660.8 Ų60.845%0.4529%0.294SS..Hα-helixtrans-65.7-45.6178.2-172.268.3000111.7L139 A140 F141 F146 F147L139-L143 VanDerWaalsContact O-CB 3.25Å; L139-L143 WeakPolarHBondContact O-CB 3.41Å; L139-L143 PolarHBondContact O-N 2.92Å; A140-L143 PolarHBondContact O-N 3.29Å; F141-L143 PolarHBondContact O-N 3.11Å; L143-F146 WeakPolarHBondContact O-CB 3.36Å; L143-F146 PolarHBondContact O-N 2.96Å; L143-F147 HydrophobicContact CD1-CE2 4.3Å; L143-F147 HydrophobicContact CG-CE2 4.28Å; L143-F147 VanDerWaalsContact O-CD2 3.23Å; L143-F147 WeakPolarHBondContact O-CD2 3.4Å; L143-F147 PolarHBondContact O-N 3.29Å
144L96.2Very high95.4Very high131 Ų13157 Ų5769%0.68628%0.283SS*.Hα-helixtrans-65.2-43.7176.9-175.364.9000111.1A140 F141 F146 F147 Y148A140-L144 WeakPolarHBondContact O-CB 3.37Å; A140-L144 PolarHBondContact O-N 2.91Å; F141-L144 PolarHBondContact O-N 3.19Å; L144-F146 VanDerWaalsContact C-N 3.29Å; L144-F146 PolarHBondContact O-N 3.38Å; L144-F147 PolarHBondContact O-N 2.96Å; L144-Y148 PolarHBondContact O-N 2.93Å
145S95Very high95.4Very high8 Ų862.9 Ų62.96%0.05631%0.306CS..Hα-helixtrans-64.9-33.2178-60.60000112.2F141 Y142 F147 Y148 Y149F141-S145 WeakPolarHBondContact CE1-OG 3.32Å; F141-S145 WeakPolarHBondContact O-CB 3.45Å; F141-S145 PolarHBondContact O-N 3.33Å; F141-S145 PolarHBondContact O-OG 3.41Å; Y142-S145 PolarHBondContact O-N 3.04Å; S145-F147 PolarHBondContact O-N 3.1Å; S145-Y148 CarbonylContact O-C 3.51Å; S145-Y148 WeakPolarHBondContact O-CB 3.32Å; S145-Y148 PolarHBondContact O-N 2.97Å; S145-Y149 WeakPolarHBondContact CB-OH 3.38Å; S145-Y149 WeakPolarHBondContact O-CD1 3.33Å; S145-Y149 VanDerWaalsContact O-CD2 3.23Å; S145-Y149 WeakPolarHBondContact O-CD2 3.44Å; S145-Y149 PolarHBondContact O-N 3.4Å
146F95.6Very high95.1Very high54 Ų5463 Ų6324%0.23731%0.307CS..Hα-helixtrans-59-48.3176.6179.5-93.1000111.9L14 C17 A18 I21 Y142 L143 L144 Y148 Y149 L150L14-F146 HydrophobicContact CD2-CD2 3.95Å; L14-F146 HydrophobicContact CD2-CE2 3.79Å; L14-F146 HydrophobicContact CD2-CZ 4.24Å; C17-F146 HydrophobicContact CB-CD2 4.38Å; A18-F146 HydrophobicContact CB-CE2 4.39Å; I21-F146 HydrophobicContact CD1-CB 4.2Å; I21-F146 HydrophobicContact CD1-CD2 4.32Å; I21-F146 HydrophobicContact CD1-CG 4.35Å; Y142-F146 VanDerWaalsContact O-CB 3.25Å; Y142-F146 WeakPolarHBondContact O-CB 3.34Å; Y142-F146 PolarHBondContact O-N 3.15Å; L143-F146 WeakPolarHBondContact O-CB 3.36Å; L143-F146 PolarHBondContact O-N 2.96Å; L144-F146 VanDerWaalsContact C-N 3.29Å; L144-F146 PolarHBondContact O-N 3.38Å; F146-Y148 VanDerWaalsContact C-N 3.29Å; F146-Y148 PolarHBondContact O-N 3.3Å; F146-Y149 PolarHBondContact O-N 3.42Å; F146-L150 PolarHBondContact O-N 3.41Å
147F95.9Very high94.8Very high128 Ų12858.8 Ų58.856%0.56129%0.294SS*.Hα-helixtrans-63.7-37.8175.9-70.1-65.8000112.2L143 L144 S145 L150 Y151L143-F147 HydrophobicContact CD1-CE2 4.3Å; L143-F147 HydrophobicContact CG-CE2 4.28Å; L143-F147 VanDerWaalsContact O-CD2 3.23Å; L143-F147 WeakPolarHBondContact O-CD2 3.4Å; L143-F147 PolarHBondContact O-N 3.29Å; L144-F147 PolarHBondContact O-N 2.96Å; S145-F147 PolarHBondContact O-N 3.1Å; F147-L150 PolarHBondContact O-N 3.09Å; F147-Y151 PolarHBondContact O-N 2.84Å
148Y96.1Very high94.4Very high62 Ų6260.9 Ų60.924%0.24331%0.305CS..Hα-helixtrans-63.5-44.9174.8175.4-102.6000112V89 T90 L93 L144 S145 F146 L150 Y151 S152V89-Y148 WeakPolarHBondContact CG1-OH 3.44Å; T90-Y148 HydrophobicContact CG2-CE1 3.47Å; T90-Y148 VanDerWaalsContact CG2-CE1 3.47Å; T90-Y148 WeakPolarHBondContact CG2-OH 3.22Å; L93-Y148 HydrophobicContact CD1-CD1 3.83Å; L93-Y148 HydrophobicContact CD1-CD2 4.3Å; L93-Y148 HydrophobicContact CD1-CE1 3.54Å; L93-Y148 HydrophobicContact CD1-CE2 4.06Å; L93-Y148 HydrophobicContact CD1-CG 4.2Å; L144-Y148 PolarHBondContact O-N 2.93Å; S145-Y148 CarbonylContact O-C 3.51Å; S145-Y148 WeakPolarHBondContact O-CB 3.32Å; S145-Y148 PolarHBondContact O-N 2.97Å; F146-Y148 VanDerWaalsContact C-N 3.29Å; F146-Y148 PolarHBondContact O-N 3.3Å; Y148-L150 VanDerWaalsContact C-N 3.3Å; Y148-L150 PolarHBondContact O-N 3.16Å; Y148-Y151 PolarHBondContact O-N 3.2Å; Y148-S152 PolarHBondContact O-N 2.96Å; Y148-S152 PolarHBondContact O-OG 2.94Å
149Y95.4Very high93.9Very high1 Ų163.1 Ų63.10%0.00432%0.321CS..Hα-helixtrans-64.5-35.7176.8-57.8-27.5000112.2T13 C17 F82 N94 S145 F146 S152 M153T13-Y149 HydrophobicContact CG2-CD2 3.55Å; T13-Y149 HydrophobicContact CG2-CE2 3.57Å; T13-Y149 HydrophobicContact CG2-CG 4.09Å; C17-Y149 HydrophobicContact CB-CD2 4.19Å; C17-Y149 HydrophobicContact CB-CE2 4.24Å; F82-Y149 HydrophobicContact CE2-CE1 4.18Å; F82-Y149 HydrophobicContact CZ-CD1 4.29Å; F82-Y149 HydrophobicContact CZ-CE1 4.31Å; N94-Y149 PolarHBondContact ND2-OH 3.28Å; N94-Y149 PolarHBondContact OD1-OH 3.05Å; N94-Y149 VanDerWaalsContact OD1-OH 3.09Å; S145-Y149 WeakPolarHBondContact CB-OH 3.38Å; S145-Y149 WeakPolarHBondContact O-CD1 3.33Å; S145-Y149 VanDerWaalsContact O-CD2 3.23Å; S145-Y149 WeakPolarHBondContact O-CD2 3.44Å; S145-Y149 PolarHBondContact O-N 3.4Å; F146-Y149 PolarHBondContact O-N 3.42Å; Y149-S152 PolarHBondContact O-N 3.17Å; Y149-M153 WeakPolarHBondContact O-CB 3.32Å; Y149-M153 PolarHBondContact O-N 3.43Å
150L95Very high92.7Very high80 Ų8068.7 Ų68.742%0.41934%0.344SS..Hα-helixtrans-62.6-49.5174.8-169.5165.7000110L14 F146 F147 Y148 M153 V154L14-L150 HydrophobicContact CD2-CB 4.16Å; F146-L150 PolarHBondContact O-N 3.41Å; F147-L150 PolarHBondContact O-N 3.09Å; Y148-L150 VanDerWaalsContact C-N 3.3Å; Y148-L150 PolarHBondContact O-N 3.16Å; L150-M153 PolarHBondContact O-N 3.47Å; L150-V154 HydrophobicContact CD2-CG2 4.28Å; L150-V154 WeakPolarHBondContact O-CG2 3.42Å; L150-V154 PolarHBondContact O-N 3.38Å; L150-V154 VanDerWaalsContact O-N 3.13Å
151Y95.3Very high92.4Very high148 Ų14869.2 Ų69.258%0.5834%0.337SS*.Hα-helixtrans-58.2-49.6176173-97.5000112F147 Y148 M153 V154 Y155F147-Y151 PolarHBondContact O-N 2.84Å; Y148-Y151 PolarHBondContact O-N 3.2Å; Y151-M153 VanDerWaalsContact C-N 3.33Å; Y151-M153 PolarHBondContact O-N 3.44Å; Y151-V154 PolarHBondContact O-N 3.21Å; Y151-Y155 WeakPolarHBondContact O-CB 3.33Å; Y151-Y155 PolarHBondContact O-N 3.3Å
152S93.1Very high92.2Very high8 Ų870.2 Ų70.26%0.05634%0.343CS..Hα-helixtrans-64.9-34.4-179.6-62.60000112.8Y10 Y148 Y149 Y155 T156Y10-S152 VanDerWaalsContact CZ-CB 3.42Å; Y148-S152 PolarHBondContact O-N 2.96Å; Y148-S152 PolarHBondContact O-OG 2.94Å; Y149-S152 PolarHBondContact O-N 3.17Å; S152-Y155 PolarHBondContact O-N 3.04Å; S152-T156 WeakPolarHBondContact O-CB 3.4Å; S152-T156 VanDerWaalsContact O-CG2 3.31Å; S152-T156 WeakPolarHBondContact O-CG2 3.15Å; S152-T156 PolarHBondContact O-N 3.3Å; S152-T156 PolarHBondContact O-OG1 2.87Å
153M93.3Very high92Very high41 Ų4174.1 Ų74.120%0.20236%0.362CS..Hα-helixtrans-60.7-48.1172.5-168.7-156.199.400111.1Y10 M11 L14 Y149 L150 Y151 T156 L157Y10-M153 HydrophobicContact CG-CB 4.48Å; M11-M153 HydrophobicContact CE-CE 4.36Å; M11-M153 HydrophobicContact CE-SD 4.45Å; M11-M153 HydrophobicContact CG-CG 4.03Å; M11-M153 HydrophobicContact CG-SD 3.74Å; L14-M153 HydrophobicContact CD1-CB 4.17Å; L14-M153 HydrophobicContact CD1-CG 4.34Å; L14-M153 HydrophobicContact CD1-SD 3.61Å; Y149-M153 WeakPolarHBondContact O-CB 3.32Å; Y149-M153 PolarHBondContact O-N 3.43Å; L150-M153 PolarHBondContact O-N 3.47Å; Y151-M153 VanDerWaalsContact C-N 3.33Å; Y151-M153 PolarHBondContact O-N 3.44Å; M153-T156 PolarHBondContact O-OG1 2.91Å; M153-L157 HydrophobicContact CE-CD1 3.49Å; M153-L157 VanDerWaalsContact CE-CD1 3.49Å; M153-L157 HydrophobicContact CG-CD1 4.24Å; M153-L157 WeakPolarHBondContact O-CB 3.05Å; M153-L157 VanDerWaalsContact O-CG 3.3Å; M153-L157 WeakPolarHBondContact O-CG 3.46Å; M153-L157 PolarHBondContact O-N 3.24Å
154V93Very high91.7Very high71 Ų7173.4 Ų73.443%0.4336%0.357SS..Hα-helixtrans-66.1-43.8179.4175.70000110.4L150 Y151 T156 L157 V158L150-V154 HydrophobicContact CD2-CG2 4.28Å; L150-V154 WeakPolarHBondContact O-CG2 3.42Å; L150-V154 PolarHBondContact O-N 3.38Å; L150-V154 VanDerWaalsContact O-N 3.13Å; Y151-V154 PolarHBondContact O-N 3.21Å; V154-T156 PolarHBondContact O-N 3.09Å; V154-L157 PolarHBondContact O-N 2.69Å; V154-V158 HydrophobicContact CG1-CG2 4.24Å; V154-V158 WeakPolarHBondContact O-CB 3.34Å; V154-V158 VanDerWaalsContact O-CG2 3.32Å; V154-V158 WeakPolarHBondContact O-CG2 3.31Å; V154-V158 PolarHBondContact O-N 3.01Å
155Y92.1Very high91.5Very high138 Ų13869.8 Ų69.854%0.54134%0.337SS..Hα-helixtrans-58.2-48.6177.5178.6-100.2000111.8Y151 S152 L157 V158 S159Y151-Y155 WeakPolarHBondContact O-CB 3.33Å; Y151-Y155 PolarHBondContact O-N 3.3Å; S152-Y155 PolarHBondContact O-N 3.04Å; Y155-L157 VanDerWaalsContact C-N 3.33Å; Y155-L157 PolarHBondContact O-N 3.37Å; Y155-V158 PolarHBondContact O-N 2.97Å; Y155-S159 VanDerWaalsContact O-CB 3.32Å; Y155-S159 WeakPolarHBondContact O-CB 3.49Å; Y155-S159 PolarHBondContact O-N 2.64Å; Y155-S159 PolarHBondContact O-OG 3.16Å
156T89.2Confident91.2Very high7 Ų773.9 Ų73.94%0.04336%0.355CS..Hα-helixtrans-67.4-29178.351.60000113.8Y10 S152 M153 V154 F160Y10-T156 HydrophobicContact CD2-CG2 4.09Å; Y10-T156 HydrophobicContact CE2-CG2 3.74Å; S152-T156 WeakPolarHBondContact O-CB 3.4Å; S152-T156 VanDerWaalsContact O-CG2 3.31Å; S152-T156 WeakPolarHBondContact O-CG2 3.15Å; S152-T156 PolarHBondContact O-N 3.3Å; S152-T156 PolarHBondContact O-OG1 2.87Å; M153-T156 PolarHBondContact O-OG1 2.91Å; V154-T156 PolarHBondContact O-N 3.09Å; T156-F160 WeakPolarHBondContact O-CD2 3.38Å
157L89.6Confident90.9Very high51 Ų5175.4 Ų75.427%0.26736%0.364SS..Hα-helixtrans-77.7-29.5174.8-75.6173.1000114.1A7 M11 M153 V154 Y155A7-L157 HydrophobicContact CB-CD2 3.75Å; A7-L157 HydrophobicContact CB-CG 4.18Å; M11-L157 HydrophobicContact CE-CD1 3.69Å; M11-L157 HydrophobicContact CE-CD2 4.04Å; M11-L157 HydrophobicContact CE-CG 4.35Å; M153-L157 HydrophobicContact CE-CD1 3.49Å; M153-L157 VanDerWaalsContact CE-CD1 3.49Å; M153-L157 HydrophobicContact CG-CD1 4.24Å; M153-L157 WeakPolarHBondContact O-CB 3.05Å; M153-L157 VanDerWaalsContact O-CG 3.3Å; M153-L157 WeakPolarHBondContact O-CG 3.46Å; M153-L157 PolarHBondContact O-N 3.24Å; V154-L157 PolarHBondContact O-N 2.69Å; Y155-L157 VanDerWaalsContact C-N 3.33Å; Y155-L157 PolarHBondContact O-N 3.37Å
158V89.9Confident90.5Very high119 Ų11971.3 Ų71.372%0.72135%0.349SS*.Hα-helixtrans-89-29.1-177.8173.40000111.6V154 Y155V154-V158 HydrophobicContact CG1-CG2 4.24Å; V154-V158 WeakPolarHBondContact O-CB 3.34Å; V154-V158 VanDerWaalsContact O-CG2 3.32Å; V154-V158 WeakPolarHBondContact O-CG2 3.31Å; V154-V158 PolarHBondContact O-N 3.01Å; Y155-V158 PolarHBondContact O-N 2.97Å
159S84.6Confident90.1Very high55 Ų5572.1 Ų72.139%0.38536%0.357SS..Hα-helixtrans-77.9-16.5-179.849.70000114.5Y155Y155-S159 VanDerWaalsContact O-CB 3.32Å; Y155-S159 WeakPolarHBondContact O-CB 3.49Å; Y155-S159 PolarHBondContact O-N 2.64Å; Y155-S159 PolarHBondContact O-OG 3.16Å
160F70.4Confident89.6Confident146 Ų14678.5 Ų78.564%0.6439%0.39SS*.  trans-134.70-173.6-61.7-77000113.1A2 T4 T156A2-F160 PolarHBondContact N-O 3.3Å; T4-F160 HydrophobicContact CG2-CB 3.82Å; T4-F160 HydrophobicContact CG2-CD2 4.34Å; T4-F160 HydrophobicContact CG2-CG 4.06Å; T156-F160 WeakPolarHBondContact O-CD2 3.38Å

Retrieved 160 of 160 residues in 55.8 ms (Link to these results)

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